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Cytochrome c oxidase subunit 6C

Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

AlphaFold DB (P09669), UniProt , Accession A0A024R9B7, Species HUMAN (Homo sapiens, Human), Gene n/a, Length 75 aa.

						>A0A024R9B7_HUMAN|A0A024R9B7
MAPEVLPKPRMRGLLARRLRNHMAVAFVLSLGVAALYKFRVADQRKKAYADFYRNYDVMKDFEEMRKAGIFQSVK
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	56.8	Low	83.7	Confident	242 Å²	242	149.4 Å²	149.4	100%	1.192	79%	0.792	S	S	*	*				0	100.8	0	-156.5	109.9	165.4	0	0	106.9
2	A	69.4	Low	84.8	Confident	89 Å²	89	156.5 Å²	156.5	74%	0.736	80%	0.8	S	S	*	*			trans	-66.8	139.8	173.9	0	0	0	0	0	108.3	E4	A2-E4 PolarHBondContact O-N 3.12Å
3	P	73	Confident	85.7	Confident	111 Å²	111	148.2 Å²	148.2	72%	0.721	78%	0.777	S	S	*	*			trans	-62.6	130.1	175.1	27	-31.7	0	0	0	108.1	V5	P3-V5 PolarHBondContact O-N 2.92Å
4	E	81.8	Confident	86.4	Confident	195 Å²	195	145.1 Å²	145.1	91%	0.911	76%	0.761	S	S	*	*			trans	-60.2	106.6	169.6	-96.8	-167.6	141.5	0	0	108.5	A2 L6	A2-E4 PolarHBondContact O-N 3.12Å; E4-L6 PolarHBondContact O-N 3.34Å
5	V	86.1	Confident	87.1	Confident	131 Å²	131	144.7 Å²	144.7	79%	0.794	76%	0.759	S	S	*	*	P	Polyproline II helix	trans	-80.7	119.1	176.7	-177.9	0	0	0	0	108.2	P3	P3-V5 PolarHBondContact O-N 2.92Å
6	L	89.3	Confident	87.7	Confident	157 Å²	157	138.5 Å²	138.5	82%	0.822	74%	0.735	S	S	*	*	P	Polyproline II helix	trans	-63.1	136.5	177.4	-67.5	172.7	0	0	0	111.1	E4	E4-L6 PolarHBondContact O-N 3.34Å
7	P	91.5	Very high	88.2	Confident	113 Å²	113	138.2 Å²	138.2	73%	0.734	72%	0.721	S	S	*	*	P	Polyproline II helix	trans	-65.5	145.1	176.2	27.7	-34.2	0	0	0	110.8	P9	P7-P9 WeakPolarHBondContact O-CD 3.41Å
8	K	92.1	Very high	88.7	Confident	180 Å²	180	139.6 Å²	139.6	78%	0.783	72%	0.715	S	S	*	*	P	Polyproline II helix	trans	-62.5	120	-179.2	-174.5	174.1	-176.4	171.7	0	110.7
9	P	94	Very high	89.1	Confident	94 Å²	94	137.7 Å²	137.7	61%	0.61	71%	0.706	S	S	*	*	P	Polyproline II helix	trans	-70.2	163.9	177.2	29.5	-35	0	0	0	111.4	P7 M11	P7-P9 WeakPolarHBondContact O-CD 3.41Å; P9-M11 PolarHBondContact O-N 2.93Å
10	R	92.4	Very high	89.5	Confident	190 Å²	190	138.5 Å²	138.5	72%	0.717	70%	0.7	S	S	*	*	P	Polyproline II helix	trans	-67.6	124.6	169.1	-71.8	-169.6	177.5	-163.6	0.9	109.4	L14	R10-L14 WeakPolarHBondContact O-CD2 3.42Å
11	M	94.7	Very high	89.9	Confident	141 Å²	141	136.2 Å²	136.2	70%	0.695	69%	0.69	S	S	*	*			trans	-112.4	-1.1	-179.7	-58.6	179.3	77.6	0	0	113.7	P9	P9-M11 PolarHBondContact O-N 2.93Å
12	R	96.3	Very high	91.8	Very high	235 Å²	235	129.6 Å²	129.6	89%	0.887	66%	0.656	S	S	*	*	S	Bend	trans	-123.4	149.5	-178.2	-66.5	-177.6	174.9	176.3	-2.2	110.9	L14	R12-L14 PolarHBondContact O-N 2.98Å
13	G	96.3	Very high	93.2	Very high	49 Å²	49	129.7 Å²	129.7	51%	0.505	64%	0.642	S	S	.	*	S	Bend	trans	66.7	19.8	176.4	0	0	0	0	0	114.7	L15 A16 R17	G13-L15 PolarHBondContact O-N 3.4Å; G13-A16 PolarHBondContact O-N 2.76Å; G13-R17 PolarHBondContact O-N 3.21Å
14	L	96.3	Very high	94.4	Very high	105 Å²	105	127.1 Å²	127.1	55%	0.55	63%	0.63	S	S	.	*	H	α-helix	trans	-57.7	-47.5	-179.3	-65.7	177.1	0	0	0	111.6	R10 R12 R17 R18	R10-L14 WeakPolarHBondContact O-CD2 3.42Å; R12-L14 PolarHBondContact O-N 2.98Å; L14-R17 PolarHBondContact O-N 3.4Å; L14-R18 PolarHBondContact O-N 3.06Å
15	L	96.9	Very high	95.2	Very high	139 Å²	139	122 Å²	122	73%	0.728	61%	0.612	S	S	*	*	H	α-helix	trans	-62.1	-47.5	177.5	-178.8	61.6	0	0	0	111.9	G13 R17 R18 L19	G13-L15 PolarHBondContact O-N 3.4Å; L15-R17 VanDerWaalsContact C-N 3.32Å; L15-R17 PolarHBondContact O-N 2.78Å; L15-R18 WeakPolarHBondContact O-CB 3.28Å; L15-R18 PolarHBondContact O-N 3.49Å; L15-L19 WeakPolarHBondContact O-CB 3.41Å; L15-L19 PolarHBondContact O-N 3.25Å
16	A	96.9	Very high	95.7	Very high	45 Å²	45	118.1 Å²	118.1	37%	0.372	59%	0.594	S	S	.	*	H	α-helix	trans	-62.7	-38.5	-179.7	0	0	0	0	0	112.1	G13 R20	G13-A16 PolarHBondContact O-N 2.76Å; A16-R20 WeakPolarHBondContact O-CG 3.37Å; A16-R20 PolarHBondContact O-N 3.08Å; A16-R20 PolarHBondContact O-NH1 3.29Å
17	R	95.6	Very high	96.2	Very high	133 Å²	133	116.7 Å²	116.7	50%	0.502	58%	0.581	S	S	.	*	H	α-helix	trans	-64.2	-46.1	173.5	-176.4	-178.9	-178.7	-174.1	0.6	111.2	G13 L14 L15 L19 R20 N21	G13-R17 PolarHBondContact O-N 3.21Å; L14-R17 PolarHBondContact O-N 3.4Å; L15-R17 VanDerWaalsContact C-N 3.32Å; L15-R17 PolarHBondContact O-N 2.78Å; R17-L19 VanDerWaalsContact C-N 3.34Å; R17-L19 PolarHBondContact O-N 3.33Å; R17-R20 PolarHBondContact O-N 3.42Å; R17-N21 VanDerWaalsContact O-CG 3.31Å; R17-N21 PolarHBondContact O-N 2.99Å; R17-N21 VanDerWaalsContact O-N 3.15Å; R17-N21 PolarHBondContact O-OD1 2.92Å
18	R	96.6	Very high	96.5	Very high	163 Å²	163	116.4 Å²	116.4	62%	0.615	58%	0.577	S	S	*	*	H	α-helix	trans	-58.8	-47.7	177.3	-174	179.3	-178.5	-176.9	2.8	110.8	L14 L15 N21 H22	L14-R18 PolarHBondContact O-N 3.06Å; L15-R18 WeakPolarHBondContact O-CB 3.28Å; L15-R18 PolarHBondContact O-N 3.49Å; R18-N21 PolarHBondContact O-N 3.49Å; R18-H22 VanDerWaalsContact CG-CE1 3.41Å; R18-H22 WeakPolarHBondContact CG-CE1 3.09Å; R18-H22 PolarHBondContact O-N 2.97Å; R18-H22 PolarHBondContact O-ND1 2.95Å
19	L	97.6	Very high	96.8	Very high	104 Å²	104	113.1 Å²	113.1	55%	0.545	57%	0.567	S	S	.	*	H	α-helix	trans	-60.2	-50.4	-179.6	-178.6	61.3	0	0	0	111.5	L15 R17 N21 H22 M23	L15-L19 WeakPolarHBondContact O-CB 3.41Å; L15-L19 PolarHBondContact O-N 3.25Å; R17-L19 VanDerWaalsContact C-N 3.34Å; R17-L19 PolarHBondContact O-N 3.33Å; L19-N21 VanDerWaalsContact C-N 3.28Å; L19-N21 PolarHBondContact O-N 2.56Å; L19-H22 PolarHBondContact O-N 2.82Å; L19-H22 VanDerWaalsContact O-N 3.14Å; L19-M23 HydrophobicContact CD1-CG 3.98Å; L19-M23 HydrophobicContact CD1-SD 4.31Å; L19-M23 HydrophobicContact CG-CG 4.19Å; L19-M23 WeakPolarHBondContact O-CB 3.42Å; L19-M23 VanDerWaalsContact O-CG 3.26Å; L19-M23 WeakPolarHBondContact O-CG 3.44Å; L19-M23 PolarHBondContact O-N 3.22Å
20	R	97.3	Very high	97	Very high	154 Å²	154	111.6 Å²	111.6	58%	0.581	56%	0.559	S	S	*	*	H	α-helix	trans	-56.3	-43	177.9	-73.2	-173.3	-59.9	-89.7	2.7	112.4	A16 R17 M23 A24	A16-R20 WeakPolarHBondContact O-CG 3.37Å; A16-R20 PolarHBondContact O-N 3.08Å; A16-R20 PolarHBondContact O-NH1 3.29Å; R17-R20 PolarHBondContact O-N 3.42Å; R20-M23 PolarHBondContact O-N 3.44Å; R20-A24 PolarHBondContact O-N 3.32Å; R20-A24 VanDerWaalsContact O-N 3.12Å
21	N	96.4	Very high	97.3	Very high	91 Å²	91	108.2 Å²	108.2	49%	0.487	56%	0.555	S	S	.	*	H	α-helix	trans	-63.8	-46.3	177.5	-69.2	9.1	0	0	0	111.5	R17 R18 L19 A24 V25	R17-N21 VanDerWaalsContact O-CG 3.31Å; R17-N21 PolarHBondContact O-N 2.99Å; R17-N21 VanDerWaalsContact O-N 3.15Å; R17-N21 PolarHBondContact O-OD1 2.92Å; R18-N21 PolarHBondContact O-N 3.49Å; L19-N21 VanDerWaalsContact C-N 3.28Å; L19-N21 PolarHBondContact O-N 2.56Å; N21-A24 PolarHBondContact O-N 3.25Å; N21-V25 WeakPolarHBondContact O-CG2 3.39Å; N21-V25 PolarHBondContact O-N 3.38Å; N21-V25 VanDerWaalsContact O-N 3.12Å
22	H	98.2	Very high	97.5	Very high	103 Å²	103	103.5 Å²	103.5	48%	0.477	54%	0.542	S	S	.	.	H	α-helix	trans	-67.8	-36.5	-179.7	-73.2	60.2	0	0	0	111.7	R18 L19 V25 A26	R18-H22 VanDerWaalsContact CG-CE1 3.41Å; R18-H22 WeakPolarHBondContact CG-CE1 3.09Å; R18-H22 PolarHBondContact O-N 2.97Å; R18-H22 PolarHBondContact O-ND1 2.95Å; L19-H22 PolarHBondContact O-N 2.82Å; L19-H22 VanDerWaalsContact O-N 3.14Å; H22-V25 PolarHBondContact O-N 2.91Å; H22-A26 VanDerWaalsContact O-CB 3.24Å; H22-A26 WeakPolarHBondContact O-CB 3.38Å; H22-A26 PolarHBondContact O-N 3.31Å
23	M	97.7	Very high	97.6	Very high	90 Å²	90	97 Å²	97	44%	0.443	53%	0.528	S	S	.	.	H	α-helix	trans	-60.4	-47.9	174.9	-72.9	-57.7	-62.7	0	0	111.1	L19 R20 V25 A26 F27	L19-M23 HydrophobicContact CD1-CG 3.98Å; L19-M23 HydrophobicContact CD1-SD 4.31Å; L19-M23 HydrophobicContact CG-CG 4.19Å; L19-M23 WeakPolarHBondContact O-CB 3.42Å; L19-M23 VanDerWaalsContact O-CG 3.26Å; L19-M23 WeakPolarHBondContact O-CG 3.44Å; L19-M23 PolarHBondContact O-N 3.22Å; R20-M23 PolarHBondContact O-N 3.44Å; M23-V25 VanDerWaalsContact C-N 3.35Å; M23-V25 PolarHBondContact O-N 3.35Å; M23-A26 PolarHBondContact O-N 3.19Å; M23-F27 HydrophobicContact CE-CD2 4.47Å; M23-F27 HydrophobicContact CE-CE2 3.7Å; M23-F27 HydrophobicContact CE-CZ 4.33Å; M23-F27 WeakPolarHBondContact O-CD2 3.49Å; M23-F27 PolarHBondContact O-N 3.45Å
24	A	97.6	Very high	97.7	Very high	58 Å²	58	97.4 Å²	97.4	48%	0.479	53%	0.527	S	S	.	.	H	α-helix	trans	-59.2	-46	177.4	0	0	0	0	0	111.8	R20 N21 A26 F27 V28	R20-A24 PolarHBondContact O-N 3.32Å; R20-A24 VanDerWaalsContact O-N 3.12Å; N21-A24 PolarHBondContact O-N 3.25Å; A24-A26 PolarHBondContact O-N 2.96Å; A24-F27 PolarHBondContact O-N 3.36Å; A24-V28 WeakPolarHBondContact O-CG2 3.38Å; A24-V28 PolarHBondContact O-N 2.78Å; A24-V28 VanDerWaalsContact O-N 3.14Å
25	V	98.3	Very high	97.8	Very high	86 Å²	86	94.5 Å²	94.5	52%	0.521	52%	0.518	S	S	.	.	H	α-helix	trans	-62.1	-43.9	176.3	173.6	0	0	0	0	111.3	N21 H22 M23 F27 V28 L29	N21-V25 WeakPolarHBondContact O-CG2 3.39Å; N21-V25 PolarHBondContact O-N 3.38Å; N21-V25 VanDerWaalsContact O-N 3.12Å; H22-V25 PolarHBondContact O-N 2.91Å; M23-V25 VanDerWaalsContact C-N 3.35Å; M23-V25 PolarHBondContact O-N 3.35Å; V25-F27 VanDerWaalsContact C-N 3.34Å; V25-F27 PolarHBondContact O-N 3.46Å; V25-V28 PolarHBondContact O-N 3.48Å; V25-L29 HydrophobicContact CG1-CD1 3.75Å; V25-L29 HydrophobicContact CG1-CG 4.21Å; V25-L29 WeakPolarHBondContact O-CB 3.22Å; V25-L29 WeakPolarHBondContact O-CG 3.4Å; V25-L29 PolarHBondContact O-N 3.19Å
26	A	98.5	Very high	97.9	Very high	51 Å²	51	92.9 Å²	92.9	42%	0.421	51%	0.51	S	S	.	.	H	α-helix	trans	-61.6	-40.7	179.8	0	0	0	0	0	112.1	H22 M23 A24 S30	H22-A26 VanDerWaalsContact O-CB 3.24Å; H22-A26 WeakPolarHBondContact O-CB 3.38Å; H22-A26 PolarHBondContact O-N 3.31Å; M23-A26 PolarHBondContact O-N 3.19Å; A24-A26 PolarHBondContact O-N 2.96Å; A26-S30 VanDerWaalsContact O-CB 3.29Å; A26-S30 WeakPolarHBondContact O-CB 3.28Å; A26-S30 PolarHBondContact O-N 3.01Å; A26-S30 PolarHBondContact O-OG 3.37Å; A26-S30 VanDerWaalsContact O-OG 3.1Å
27	F	98.4	Very high	98	Very high	127 Å²	127	97.4 Å²	97.4	56%	0.557	52%	0.518	S	S	*	.	H	α-helix	trans	-64.3	-44.2	175	-83.9	-68.7	0	0	0	112.5	M23 A24 V25 S30 L31	M23-F27 HydrophobicContact CE-CD2 4.47Å; M23-F27 HydrophobicContact CE-CE2 3.7Å; M23-F27 HydrophobicContact CE-CZ 4.33Å; M23-F27 WeakPolarHBondContact O-CD2 3.49Å; M23-F27 PolarHBondContact O-N 3.45Å; A24-F27 PolarHBondContact O-N 3.36Å; V25-F27 VanDerWaalsContact C-N 3.34Å; V25-F27 PolarHBondContact O-N 3.46Å; F27-S30 PolarHBondContact O-N 3.1Å; F27-S30 PolarHBondContact O-OG 3.44Å; F27-S30 VanDerWaalsContact O-OG 3.05Å; F27-L31 WeakPolarHBondContact O-CB 3.2Å; F27-L31 VanDerWaalsContact O-CG 3.28Å; F27-L31 WeakPolarHBondContact O-CG 3.33Å; F27-L31 PolarHBondContact O-N 3.48Å
28	V	98.6	Very high	98.1	Very high	106 Å²	106	96.3 Å²	96.3	64%	0.642	52%	0.517	S	S	*	.	H	α-helix	trans	-63.4	-45.2	178.2	173.3	0	0	0	0	110.7	A24 V25 G32	A24-V28 WeakPolarHBondContact O-CG2 3.38Å; A24-V28 PolarHBondContact O-N 2.78Å; A24-V28 VanDerWaalsContact O-N 3.14Å; V25-V28 PolarHBondContact O-N 3.48Å; V28-G32 PolarHBondContact O-N 3.37Å
29	L	98.6	Very high	98.2	Very high	111 Å²	111	94.9 Å²	94.9	58%	0.581	52%	0.515	S	S	*	.	H	α-helix	trans	-65.4	-43.5	178.9	-69.8	176.3	0	0	0	112.1	V25 G32 V33	V25-L29 HydrophobicContact CG1-CD1 3.75Å; V25-L29 HydrophobicContact CG1-CG 4.21Å; V25-L29 WeakPolarHBondContact O-CB 3.22Å; V25-L29 WeakPolarHBondContact O-CG 3.4Å; V25-L29 PolarHBondContact O-N 3.19Å; L29-G32 PolarHBondContact O-N 2.97Å; L29-V33 WeakPolarHBondContact O-CG2 3.42Å; L29-V33 PolarHBondContact O-N 3.12Å
30	S	98.4	Very high	98.2	Very high	63 Å²	63	98.2 Å²	98.2	44%	0.441	52%	0.521	S	S	.	.	H	α-helix	trans	-65.4	-43.4	-179.2	66.1	0	0	0	0	112	A26 F27 G32 V33 A34	A26-S30 VanDerWaalsContact O-CB 3.29Å; A26-S30 WeakPolarHBondContact O-CB 3.28Å; A26-S30 PolarHBondContact O-N 3.01Å; A26-S30 PolarHBondContact O-OG 3.37Å; A26-S30 VanDerWaalsContact O-OG 3.1Å; F27-S30 PolarHBondContact O-N 3.1Å; F27-S30 PolarHBondContact O-OG 3.44Å; F27-S30 VanDerWaalsContact O-OG 3.05Å; S30-G32 VanDerWaalsContact C-N 3.34Å; S30-V33 PolarHBondContact O-N 2.91Å; S30-A34 WeakPolarHBondContact O-CB 3.34Å; S30-A34 PolarHBondContact O-N 3.15Å
31	L	98.6	Very high	98.2	Very high	119 Å²	119	93.6 Å²	93.6	62%	0.623	51%	0.51	S	S	*	.	H	α-helix	trans	-64.1	-40.1	173.9	-68.9	175.7	0	0	0	111.7	F27 A34 A35	F27-L31 WeakPolarHBondContact O-CB 3.2Å; F27-L31 VanDerWaalsContact O-CG 3.28Å; F27-L31 WeakPolarHBondContact O-CG 3.33Å; F27-L31 PolarHBondContact O-N 3.48Å; L31-A34 PolarHBondContact O-N 3.42Å; L31-A35 WeakPolarHBondContact O-CB 3.4Å; L31-A35 PolarHBondContact O-N 3.33Å
32	G	98.5	Very high	98.3	Very high	41 Å²	41	90.2 Å²	90.2	42%	0.423	49%	0.494	S	S	.	.	H	α-helix	trans	-60.3	-46.6	175.3	0	0	0	0	0	112.6	V28 L29 S30 A35 L36	V28-G32 PolarHBondContact O-N 3.37Å; L29-G32 PolarHBondContact O-N 2.97Å; S30-G32 VanDerWaalsContact C-N 3.34Å; G32-A35 PolarHBondContact O-N 3.32Å; G32-L36 WeakPolarHBondContact O-CB 3.46Å; G32-L36 PolarHBondContact O-N 2.87Å
33	V	98.5	Very high	98.3	Very high	98 Å²	98	87.4 Å²	87.4	59%	0.594	48%	0.483	S	S	*	.	H	α-helix	trans	-64.6	-43.3	176.6	172.2	0	0	0	0	111.2	L29 S30 A35 L36 Y37	L29-V33 WeakPolarHBondContact O-CG2 3.42Å; L29-V33 PolarHBondContact O-N 3.12Å; S30-V33 PolarHBondContact O-N 2.91Å; V33-A35 PolarHBondContact O-N 3.45Å; V33-L36 PolarHBondContact O-N 2.81Å; V33-Y37 WeakPolarHBondContact O-CB 3.27Å; V33-Y37 PolarHBondContact O-N 3.04Å
34	A	98.6	Very high	98.3	Very high	59 Å²	59	89.1 Å²	89.1	49%	0.488	49%	0.49	S	S	.	.	H	α-helix	trans	-61.4	-44.3	177.7	0	0	0	0	0	112	S30 L31 Y37 K38	S30-A34 WeakPolarHBondContact O-CB 3.34Å; S30-A34 PolarHBondContact O-N 3.15Å; L31-A34 PolarHBondContact O-N 3.42Å; A34-Y37 PolarHBondContact O-N 2.87Å; A34-K38 WeakPolarHBondContact O-CB 3.47Å; A34-K38 PolarHBondContact O-N 2.99Å
35	A	98.5	Very high	98.3	Very high	43 Å²	43	93.4 Å²	93.4	36%	0.355	49%	0.493	S	S	.	.	H	α-helix	trans	-63.4	-45.4	175.6	0	0	0	0	0	111.6	L31 G32 V33 Y37 K38 F39	L31-A35 WeakPolarHBondContact O-CB 3.4Å; L31-A35 PolarHBondContact O-N 3.33Å; G32-A35 PolarHBondContact O-N 3.32Å; V33-A35 PolarHBondContact O-N 3.45Å; A35-Y37 VanDerWaalsContact C-N 3.34Å; A35-Y37 PolarHBondContact O-N 3.45Å; A35-K38 PolarHBondContact O-N 3.5Å; A35-F39 WeakPolarHBondContact O-CD2 3.35Å; A35-F39 PolarHBondContact O-N 3.21Å
36	L	98.4	Very high	98.3	Very high	106 Å²	106	95.6 Å²	95.6	56%	0.555	50%	0.496	S	S	*	.	H	α-helix	trans	-58.3	-47.1	177.7	-176.6	66.1	0	0	0	111.3	G32 V33 K38 F39 R40	G32-L36 WeakPolarHBondContact O-CB 3.46Å; G32-L36 PolarHBondContact O-N 2.87Å; V33-L36 PolarHBondContact O-N 2.81Å; L36-K38 PolarHBondContact O-N 3.45Å; L36-F39 PolarHBondContact O-N 3.49Å; L36-R40 HydrophobicContact CD1-CG 3.63Å; L36-R40 HydrophobicContact CG-CG 4.31Å; L36-R40 VanDerWaalsContact O-CB 3.24Å; L36-R40 WeakPolarHBondContact O-CB 3.26Å; L36-R40 WeakPolarHBondContact O-CG 3.23Å; L36-R40 PolarHBondContact O-N 2.98Å
37	Y	98.6	Very high	98.3	Very high	140 Å²	140	99.6 Å²	99.6	55%	0.549	50%	0.504	S	S	.	.	H	α-helix	trans	-63	-42.5	178.3	-172.4	-93.7	0	0	0	112	V33 A34 A35 F39 V41 A42	V33-Y37 WeakPolarHBondContact O-CB 3.27Å; V33-Y37 PolarHBondContact O-N 3.04Å; A34-Y37 PolarHBondContact O-N 2.87Å; A35-Y37 VanDerWaalsContact C-N 3.34Å; A35-Y37 PolarHBondContact O-N 3.45Å; Y37-F39 PolarHBondContact O-N 3.25Å; Y37-V41 HydrophobicContact CD2-CB 4.04Å; Y37-V41 HydrophobicContact CD2-CG2 3.77Å; Y37-V41 HydrophobicContact CE1-CB 4.39Å; Y37-V41 HydrophobicContact CE1-CG1 4.44Å; Y37-V41 HydrophobicContact CE2-CB 3.9Å; Y37-V41 HydrophobicContact CE2-CG1 3.9Å; Y37-V41 HydrophobicContact CE2-CG2 3.84Å; Y37-V41 HydrophobicContact CG-CB 4.36Å; Y37-V41 HydrophobicContact CG-CG2 4.4Å; Y37-V41 WeakPolarHBondContact O-CA 3.49Å; Y37-V41 VanDerWaalsContact O-CB 3.29Å; Y37-V41 WeakPolarHBondContact O-CB 3.34Å; Y37-V41 PolarHBondContact O-N 3.02Å; Y37-A42 PolarHBondContact O-N 2.91Å; Y37-A42 VanDerWaalsContact O-N 3.11Å
38	K	98.4	Very high	98.2	Very high	110 Å²	110	96.2 Å²	96.2	48%	0.478	50%	0.5	S	S	.	.	I	π-helix	trans	-56.7	-54.1	176.7	178.3	179.4	175.1	179	0	111.2	A34 A35 L36 A42 D43	A34-K38 WeakPolarHBondContact O-CB 3.47Å; A34-K38 PolarHBondContact O-N 2.99Å; A35-K38 PolarHBondContact O-N 3.5Å; L36-K38 PolarHBondContact O-N 3.45Å; K38-A42 WeakPolarHBondContact O-CB 3.36Å; K38-A42 PolarHBondContact O-N 3.06Å; K38-D43 WeakPolarHBondContact O-CB 3.47Å; K38-D43 PolarHBondContact O-N 3.11Å
39	F	97.9	Very high	98.2	Very high	132 Å²	132	98.3 Å²	98.3	58%	0.579	50%	0.497	S	S	*	.	I	π-helix	trans	-75.9	-40.4	-173.7	-68	-64.1	0	0	0	113.2	A35 L36 Y37	A35-F39 WeakPolarHBondContact O-CD2 3.35Å; A35-F39 PolarHBondContact O-N 3.21Å; L36-F39 PolarHBondContact O-N 3.49Å; Y37-F39 PolarHBondContact O-N 3.25Å
40	R	97.6	Very high	98.2	Very high	174 Å²	174	95.9 Å²	95.9	66%	0.657	49%	0.493	S	S	*	.	I	π-helix	trans	-84	-27.9	-175.4	-65.6	-65.9	-168.1	126.9	0.2	113.9	L36 Q44	L36-R40 HydrophobicContact CD1-CG 3.63Å; L36-R40 HydrophobicContact CG-CG 4.31Å; L36-R40 VanDerWaalsContact O-CB 3.24Å; L36-R40 WeakPolarHBondContact O-CB 3.26Å; L36-R40 WeakPolarHBondContact O-CG 3.23Å; L36-R40 PolarHBondContact O-N 2.98Å; R40-Q44 WeakPolarHBondContact O-CB 3.4Å; R40-Q44 PolarHBondContact O-OE1 2.91Å
41	V	98.1	Very high	98.2	Very high	58 Å²	58	96.6 Å²	96.6	35%	0.352	49%	0.492	S	S	.	.	I	π-helix	trans	-111.9	-60.1	-176.9	-174.6	0	0	0	0	110.3	Y37 R45	Y37-V41 HydrophobicContact CD2-CB 4.04Å; Y37-V41 HydrophobicContact CD2-CG2 3.77Å; Y37-V41 HydrophobicContact CE1-CB 4.39Å; Y37-V41 HydrophobicContact CE1-CG1 4.44Å; Y37-V41 HydrophobicContact CE2-CB 3.9Å; Y37-V41 HydrophobicContact CE2-CG1 3.9Å; Y37-V41 HydrophobicContact CE2-CG2 3.84Å; Y37-V41 HydrophobicContact CG-CB 4.36Å; Y37-V41 HydrophobicContact CG-CG2 4.4Å; Y37-V41 WeakPolarHBondContact O-CA 3.49Å; Y37-V41 VanDerWaalsContact O-CB 3.29Å; Y37-V41 WeakPolarHBondContact O-CB 3.34Å; Y37-V41 PolarHBondContact O-N 3.02Å; V41-R45 VanDerWaalsContact O-CB 3.23Å; V41-R45 WeakPolarHBondContact O-CB 3.42Å; V41-R45 PolarHBondContact O-N 3.48Å
42	A	98.2	Very high	98.1	Very high	20 Å²	20	96.2 Å²	96.2	17%	0.165	49%	0.485	C	S	.	.	I	π-helix	trans	-68.2	-51.5	-170.2	0	0	0	0	0	112.3	Y37 K38 R45 K46	Y37-A42 PolarHBondContact O-N 2.91Å; Y37-A42 VanDerWaalsContact O-N 3.11Å; K38-A42 WeakPolarHBondContact O-CB 3.36Å; K38-A42 PolarHBondContact O-N 3.06Å; A42-R45 PolarHBondContact O-N 3.46Å; A42-K46 WeakPolarHBondContact O-CG 3.14Å; A42-K46 PolarHBondContact O-N 3.37Å
43	D	98	Very high	98	Very high	44 Å²	44	101.2 Å²	101.2	24%	0.235	49%	0.493	C	S	.	.	I	π-helix	trans	-76.8	-34.9	-175.8	-67.2	-17.2	0	0	0	111.6	K38 R45 K46 K47	K38-D43 WeakPolarHBondContact O-CB 3.47Å; K38-D43 PolarHBondContact O-N 3.11Å; D43-R45 VanDerWaalsContact C-N 3.32Å; D43-R45 PolarHBondContact O-N 2.92Å; D43-K46 PolarHBondContact O-N 3.44Å; D43-K46 IonicContact OD1-NZ 3.32Å; D43-K46 PolarHBondContact OD1-NZ 3.43Å; D43-K47 WeakPolarHBondContact O-CB 3.45Å; D43-K47 PolarHBondContact O-N 2.91Å
44	Q	97.6	Very high	98	Very high	125 Å²	125	105.6 Å²	105.6	58%	0.584	50%	0.498	S	S	*	.	H	α-helix	trans	-59.8	-42.7	170.6	-174.4	171.7	-16.6	0	0	111.7	R40 K47 A48	R40-Q44 WeakPolarHBondContact O-CB 3.4Å; R40-Q44 PolarHBondContact O-OE1 2.91Å; Q44-K47 PolarHBondContact O-N 3.31Å; Q44-A48 WeakPolarHBondContact O-CB 3.29Å; Q44-A48 PolarHBondContact O-N 3.4Å
45	R	98.1	Very high	97.8	Very high	148 Å²	148	109.7 Å²	109.7	56%	0.558	51%	0.512	S	S	*	.	H	α-helix	trans	-64	-48.3	175.1	-176.1	176.7	61.9	-173.1	-0.8	111.4	V41 A42 D43 K47 A48 Y49	V41-R45 VanDerWaalsContact O-CB 3.23Å; V41-R45 WeakPolarHBondContact O-CB 3.42Å; V41-R45 PolarHBondContact O-N 3.48Å; A42-R45 PolarHBondContact O-N 3.46Å; D43-R45 VanDerWaalsContact C-N 3.32Å; D43-R45 PolarHBondContact O-N 2.92Å; R45-K47 VanDerWaalsContact C-N 3.27Å; R45-K47 PolarHBondContact O-N 2.92Å; R45-A48 PolarHBondContact O-N 3.28Å; R45-A48 VanDerWaalsContact O-N 3.15Å; R45-Y49 HydrophobicContact CG-CD2 4Å; R45-Y49 HydrophobicContact CG-CE2 3.78Å; R45-Y49 VanDerWaalsContact O-CD2 3.27Å; R45-Y49 WeakPolarHBondContact O-CD2 3.24Å; R45-Y49 PolarHBondContact O-N 2.93Å; R45-Y49 VanDerWaalsContact O-N 3.12Å
46	K	98.2	Very high	97.7	Very high	132 Å²	132	111.2 Å²	111.2	57%	0.574	51%	0.509	S	S	*	.	H	α-helix	trans	-56.1	-44.3	176.8	-69.8	169.7	-165.5	160.6	0	111.6	A42 D43 Y49 A50	A42-K46 WeakPolarHBondContact O-CG 3.14Å; A42-K46 PolarHBondContact O-N 3.37Å; D43-K46 PolarHBondContact O-N 3.44Å; D43-K46 IonicContact OD1-NZ 3.32Å; D43-K46 PolarHBondContact OD1-NZ 3.43Å; K46-Y49 PolarHBondContact O-N 2.93Å; K46-A50 WeakPolarHBondContact O-CB 3.38Å; K46-A50 PolarHBondContact O-N 3.05Å
47	K	97.9	Very high	97.7	Very high	135 Å²	135	110.5 Å²	110.5	59%	0.587	51%	0.506	S	S	*	.	H	α-helix	trans	-61.6	-45.5	176.7	-177.9	176.3	177.3	-176.5	0	111.6	D43 Q44 R45 Y49 A50 D51	D43-K47 WeakPolarHBondContact O-CB 3.45Å; D43-K47 PolarHBondContact O-N 2.91Å; Q44-K47 PolarHBondContact O-N 3.31Å; R45-K47 VanDerWaalsContact C-N 3.27Å; R45-K47 PolarHBondContact O-N 2.92Å; K47-Y49 VanDerWaalsContact C-N 3.34Å; K47-Y49 PolarHBondContact O-N 2.89Å; K47-A50 PolarHBondContact O-N 3.1Å; K47-D51 WeakPolarHBondContact CE-OD2 3.4Å; K47-D51 WeakPolarHBondContact CG-OD2 3.28Å; K47-D51 WeakPolarHBondContact O-CB 3.38Å; K47-D51 VanDerWaalsContact O-CG 3.3Å; K47-D51 PolarHBondContact O-N 2.89Å
48	A	97.9	Very high	97.6	Very high	57 Å²	57	108.1 Å²	108.1	47%	0.471	51%	0.506	S	S	.	.	H	α-helix	trans	-58.8	-42.4	178.9	0	0	0	0	0	112.9	Q44 R45 F52	Q44-A48 WeakPolarHBondContact O-CB 3.29Å; Q44-A48 PolarHBondContact O-N 3.4Å; R45-A48 PolarHBondContact O-N 3.28Å; R45-A48 VanDerWaalsContact O-N 3.15Å; A48-F52 WeakPolarHBondContact O-CB 3.36Å; A48-F52 PolarHBondContact O-N 3.14Å
49	Y	97.9	Very high	97.5	Very high	149 Å²	149	108.7 Å²	108.7	58%	0.584	51%	0.512	S	S	*	.	H	α-helix	trans	-67	-44.1	175.3	-81.2	-104.6	0	0	0	111.6	R45 K46 K47 D51 F52 Y53	R45-Y49 HydrophobicContact CG-CD2 4Å; R45-Y49 HydrophobicContact CG-CE2 3.78Å; R45-Y49 VanDerWaalsContact O-CD2 3.27Å; R45-Y49 WeakPolarHBondContact O-CD2 3.24Å; R45-Y49 PolarHBondContact O-N 2.93Å; R45-Y49 VanDerWaalsContact O-N 3.12Å; K46-Y49 PolarHBondContact O-N 2.93Å; K47-Y49 VanDerWaalsContact C-N 3.34Å; K47-Y49 PolarHBondContact O-N 2.89Å; Y49-D51 VanDerWaalsContact C-N 3.35Å; Y49-D51 PolarHBondContact O-N 3.26Å; Y49-F52 PolarHBondContact O-N 2.93Å; Y49-Y53 HydrophobicContact CD1-CE2 4.44Å; Y49-Y53 VanDerWaalsContact O-CD2 3.26Å; Y49-Y53 WeakPolarHBondContact O-CD2 3.45Å; Y49-Y53 PolarHBondContact O-N 3.42Å; Y49-Y53 VanDerWaalsContact O-N 3.1Å
50	A	98.1	Very high	97.4	Very high	61 Å²	61	108.5 Å²	108.5	50%	0.504	51%	0.51	S	S	.	.	H	α-helix	trans	-61.4	-43.6	177.1	0	0	0	0	0	111.9	K46 K47 Y53 R54	K46-A50 WeakPolarHBondContact O-CB 3.38Å; K46-A50 PolarHBondContact O-N 3.05Å; K47-A50 PolarHBondContact O-N 3.1Å; A50-Y53 PolarHBondContact O-N 3.05Å; A50-R54 WeakPolarHBondContact O-CB 3.29Å; A50-R54 PolarHBondContact O-N 3.48Å
51	D	97.8	Very high	97.4	Very high	78 Å²	78	102.2 Å²	102.2	42%	0.417	49%	0.49	S	S	.	.	H	α-helix	trans	-66.1	-39.1	178.7	-73.3	-17.6	0	0	0	111.5	K47 Y49 R54	K47-D51 WeakPolarHBondContact CE-OD2 3.4Å; K47-D51 WeakPolarHBondContact CG-OD2 3.28Å; K47-D51 WeakPolarHBondContact O-CB 3.38Å; K47-D51 VanDerWaalsContact O-CG 3.3Å; K47-D51 PolarHBondContact O-N 2.89Å; Y49-D51 VanDerWaalsContact C-N 3.35Å; Y49-D51 PolarHBondContact O-N 3.26Å; D51-R54 PolarHBondContact O-N 3.4Å
52	F	97.1	Very high	97.3	Very high	110 Å²	110	102.4 Å²	102.4	48%	0.482	49%	0.486	S	S	.	.	H	α-helix	trans	-58.2	-53.9	173.8	177.9	-94.4	0	0	0	111	A48 Y49 R54 Y56	A48-F52 WeakPolarHBondContact O-CB 3.36Å; A48-F52 PolarHBondContact O-N 3.14Å; Y49-F52 PolarHBondContact O-N 2.93Å; F52-R54 VanDerWaalsContact C-N 3.29Å; F52-R54 PolarHBondContact O-N 2.98Å; F52-Y56 HydrophobicContact CE1-CD1 4.21Å; F52-Y56 AromaticContact CE1-CD2 3.81Å; F52-Y56 HydrophobicContact CE1-CD2 3.81Å; F52-Y56 HydrophobicContact CE1-CE1 4.37Å; F52-Y56 HydrophobicContact CE1-CE2 4.02Å; F52-Y56 AromaticContact CE1-CG 3.92Å; F52-Y56 HydrophobicContact CE1-CG 3.92Å; F52-Y56 HydrophobicContact CE2-CD2 4.4Å; F52-Y56 AromaticContact CZ-CD2 3.66Å; F52-Y56 HydrophobicContact CZ-CD2 3.66Å; F52-Y56 AromaticContact CZ-CE2 3.64Å; F52-Y56 HydrophobicContact CZ-CE2 3.64Å; F52-Y56 HydrophobicContact CZ-CG 4.27Å; F52-Y56 WeakPolarHBondContact O-CB 3.34Å
53	Y	97.2	Very high	97.2	Very high	147 Å²	147	104.3 Å²	104.3	58%	0.576	49%	0.492	S	S	*	.	H	α-helix	trans	-75.7	-14.2	-176.5	-74.4	-68.2	0	0	0	114.6	Y49 A50 N55 Y56	Y49-Y53 HydrophobicContact CD1-CE2 4.44Å; Y49-Y53 VanDerWaalsContact O-CD2 3.26Å; Y49-Y53 WeakPolarHBondContact O-CD2 3.45Å; Y49-Y53 PolarHBondContact O-N 3.42Å; Y49-Y53 VanDerWaalsContact O-N 3.1Å; A50-Y53 PolarHBondContact O-N 3.05Å; Y53-N55 PolarHBondContact O-N 3.5Å; Y53-Y56 AromaticContact CD1-CD1 3.88Å; Y53-Y56 HydrophobicContact CD1-CD1 3.88Å; Y53-Y56 HydrophobicContact CD1-CG 4.33Å; Y53-Y56 AromaticContact CE1-CD1 3.91Å; Y53-Y56 HydrophobicContact CE1-CD1 3.91Å; Y53-Y56 HydrophobicContact CE1-CE1 4.28Å; Y53-Y56 PolarHBondContact O-N 2.8Å
54	R	97.2	Very high	97.1	Very high	189 Å²	189	107.3 Å²	107.3	71%	0.713	50%	0.504	S	S	*	.	H	α-helix	trans	-55.9	-38.2	-176	-173.5	172.6	-177.4	166.4	1	113.3	A50 D51 F52	A50-R54 WeakPolarHBondContact O-CB 3.29Å; A50-R54 PolarHBondContact O-N 3.48Å; D51-R54 PolarHBondContact O-N 3.4Å; F52-R54 VanDerWaalsContact C-N 3.29Å; F52-R54 PolarHBondContact O-N 2.98Å
55	N	95.7	Very high	97	Very high	146 Å²	146	104.6 Å²	104.6	78%	0.781	49%	0.492	S	S	*	.	T	Hydrogen-bonded Turn	trans	-131.1	22.9	-179.6	-55.5	-52.1	0	0	0	111.6	Y53 D57	Y53-N55 PolarHBondContact O-N 3.5Å; N55-D57 PolarHBondContact O-N 3.24Å
56	Y	97.2	Very high	96.9	Very high	75 Å²	75	100.4 Å²	100.4	29%	0.294	48%	0.477	S	S	.	.			trans	-72.8	119.6	-177.5	-179.2	-120	0	0	0	110.3	F52 Y53 V58 D61	F52-Y56 HydrophobicContact CE1-CD1 4.21Å; F52-Y56 AromaticContact CE1-CD2 3.81Å; F52-Y56 HydrophobicContact CE1-CD2 3.81Å; F52-Y56 HydrophobicContact CE1-CE1 4.37Å; F52-Y56 HydrophobicContact CE1-CE2 4.02Å; F52-Y56 AromaticContact CE1-CG 3.92Å; F52-Y56 HydrophobicContact CE1-CG 3.92Å; F52-Y56 HydrophobicContact CE2-CD2 4.4Å; F52-Y56 AromaticContact CZ-CD2 3.66Å; F52-Y56 HydrophobicContact CZ-CD2 3.66Å; F52-Y56 AromaticContact CZ-CE2 3.64Å; F52-Y56 HydrophobicContact CZ-CE2 3.64Å; F52-Y56 HydrophobicContact CZ-CG 4.27Å; F52-Y56 WeakPolarHBondContact O-CB 3.34Å; Y53-Y56 AromaticContact CD1-CD1 3.88Å; Y53-Y56 HydrophobicContact CD1-CD1 3.88Å; Y53-Y56 HydrophobicContact CD1-CG 4.33Å; Y53-Y56 AromaticContact CE1-CD1 3.91Å; Y53-Y56 HydrophobicContact CE1-CD1 3.91Å; Y53-Y56 HydrophobicContact CE1-CE1 4.28Å; Y53-Y56 PolarHBondContact O-N 2.8Å; Y56-V58 HydrophobicContact CD1-CG2 3.93Å; Y56-V58 HydrophobicContact CE1-CB 4.3Å; Y56-V58 HydrophobicContact CE1-CG2 3.65Å; Y56-D61 HydrophobicContact CE2-CB 3.63Å; Y56-D61 WeakPolarHBondContact CE2-OD2 3.43Å; Y56-D61 PolarHBondContact OH-OD2 3.44Å
57	D	96.9	Very high	96.7	Very high	90 Å²	90	101.5 Å²	101.5	48%	0.481	48%	0.481	S	S	.	.			trans	-102.6	107.1	171.3	-178.9	-15.1	0	0	0	108.8	N55 M59 K60 D61	N55-D57 PolarHBondContact O-N 3.24Å; D57-M59 VanDerWaalsContact C-N 3.29Å; D57-M59 PolarHBondContact O-N 3.15Å; D57-M59 PolarHBondContact OD1-N 3.4Å; D57-K60 HydrophobicContact CB-CB 3.84Å; D57-K60 PolarHBondContact O-N 3.48Å; D57-K60 PolarHBondContact OD1-N 3.3Å; D57-K60 VanDerWaalsContact OD1-N 3.12Å; D57-D61 PolarHBondContact O-N 3.12Å
58	V	96.3	Very high	96.7	Very high	90 Å²	90	98.6 Å²	98.6	55%	0.545	48%	0.483	S	S	.	.	H	α-helix	trans	-60.8	-38.8	-178.4	-173.7	0	0	0	0	111.4	Y56 F62	Y56-V58 HydrophobicContact CD1-CG2 3.93Å; Y56-V58 HydrophobicContact CE1-CB 4.3Å; Y56-V58 HydrophobicContact CE1-CG2 3.65Å; V58-F62 VanDerWaalsContact O-CB 3.28Å; V58-F62 WeakPolarHBondContact O-CB 3.41Å; V58-F62 PolarHBondContact O-N 3.14Å
59	M	96.4	Very high	96.5	Very high	122 Å²	122	98.6 Å²	98.6	60%	0.601	49%	0.488	S	S	*	.	H	α-helix	trans	-72.7	-37.4	-177.3	-70.3	-56.6	-59	0	0	111	D57 F62 E63	D57-M59 VanDerWaalsContact C-N 3.29Å; D57-M59 PolarHBondContact O-N 3.15Å; D57-M59 PolarHBondContact OD1-N 3.4Å; M59-F62 HydrophobicContact CE-CD1 4.42Å; M59-E63 WeakPolarHBondContact O-CB 3.34Å; M59-E63 WeakPolarHBondContact O-CG 3.16Å; M59-E63 PolarHBondContact O-N 3.29Å
60	K	96.7	Very high	96.3	Very high	128 Å²	128	96.8 Å²	96.8	56%	0.557	49%	0.487	S	S	*	.	H	α-helix	trans	-62.3	-49.2	173.5	-176.7	-178.5	171.5	-173.9	0	111.4	D57 F62 E63 E64	D57-K60 HydrophobicContact CB-CB 3.84Å; D57-K60 PolarHBondContact O-N 3.48Å; D57-K60 PolarHBondContact OD1-N 3.3Å; D57-K60 VanDerWaalsContact OD1-N 3.12Å; K60-F62 VanDerWaalsContact C-N 3.35Å; K60-F62 PolarHBondContact O-N 3.36Å; K60-E63 PolarHBondContact O-N 3.12Å; K60-E64 WeakPolarHBondContact CE-OE1 3.48Å; K60-E64 WeakPolarHBondContact O-CG 3.24Å; K60-E64 PolarHBondContact O-N 2.82Å
61	D	96.5	Very high	96.2	Very high	42 Å²	42	97 Å²	97	23%	0.225	48%	0.477	C	S	.	.	H	α-helix	trans	-62.3	-42.2	179.2	-169.6	43.6	0	0	0	111.6	Y56 D57 E63 E64 M65	Y56-D61 HydrophobicContact CE2-CB 3.63Å; Y56-D61 WeakPolarHBondContact CE2-OD2 3.43Å; Y56-D61 PolarHBondContact OH-OD2 3.44Å; D57-D61 PolarHBondContact O-N 3.12Å; D61-E63 PolarHBondContact O-N 3.06Å; D61-E64 PolarHBondContact O-N 3.34Å; D61-M65 WeakPolarHBondContact O-CG 3.38Å; D61-M65 PolarHBondContact O-N 2.94Å; D61-M65 VanDerWaalsContact OD2-CE 3.28Å; D61-M65 WeakPolarHBondContact OD2-CE 3.41Å
62	F	96	Very high	96	Very high	62 Å²	62	102.9 Å²	102.9	27%	0.272	50%	0.502	S	S	.	.	H	α-helix	trans	-58.6	-47.6	172.6	170.1	-99.3	0	0	0	112.5	V58 M59 K60 E64 M65 R66 F71 V74	V58-F62 VanDerWaalsContact O-CB 3.28Å; V58-F62 WeakPolarHBondContact O-CB 3.41Å; V58-F62 PolarHBondContact O-N 3.14Å; M59-F62 HydrophobicContact CE-CD1 4.42Å; K60-F62 VanDerWaalsContact C-N 3.35Å; K60-F62 PolarHBondContact O-N 3.36Å; F62-E64 VanDerWaalsContact C-N 3.32Å; F62-E64 PolarHBondContact O-N 2.96Å; F62-M65 PolarHBondContact O-N 3.38Å; F62-R66 WeakPolarHBondContact O-CB 3.49Å; F62-R66 PolarHBondContact O-N 3.32Å; F62-F71 HydrophobicContact CD2-CD2 4.43Å; F62-F71 AromaticContact CD2-CE2 3.53Å; F62-F71 HydrophobicContact CD2-CE2 3.53Å; F62-F71 AromaticContact CD2-CZ 3.8Å; F62-F71 HydrophobicContact CD2-CZ 3.8Å; F62-F71 AromaticContact CE2-CD2 3.96Å; F62-F71 HydrophobicContact CE2-CD2 3.96Å; F62-F71 AromaticContact CE2-CE2 3.5Å; F62-F71 HydrophobicContact CE2-CE2 3.5Å; F62-F71 VanDerWaalsContact CE2-CE2 3.5Å; F62-F71 HydrophobicContact CE2-CZ 4.02Å; F62-F71 HydrophobicContact CG-CE2 4.49Å; F62-F71 HydrophobicContact CZ-CE2 4.43Å; F62-V74 HydrophobicContact CZ-CB 4.45Å; F62-V74 HydrophobicContact CZ-CG1 4.17Å; F62-V74 HydrophobicContact CZ-CG2 4.32Å
63	E	96.2	Very high	95.9	Very high	61 Å²	61	102.9 Å²	102.9	29%	0.285	52%	0.516	S	S	.	.	H	α-helix	trans	-65.1	-34.4	178.6	-79.2	-63	135.9	0	0	112.5	M59 K60 D61 R66 K67	M59-E63 WeakPolarHBondContact O-CB 3.34Å; M59-E63 WeakPolarHBondContact O-CG 3.16Å; M59-E63 PolarHBondContact O-N 3.29Å; K60-E63 PolarHBondContact O-N 3.12Å; D61-E63 PolarHBondContact O-N 3.06Å; E63-R66 IonicContact OE1-NE 2.87Å; E63-R66 PolarHBondContact OE1-NE 2.79Å; E63-R66 IonicContact OE2-CZ 2.98Å; E63-R66 VanDerWaalsContact OE2-CZ 3.32Å; E63-R66 IonicContact OE2-NE 2.76Å; E63-R66 PolarHBondContact OE2-NE 3.48Å; E63-R66 IonicContact OE2-NH2 3.21Å; E63-R66 PolarHBondContact OE2-NH2 3.48Å; E63-K67 WeakPolarHBondContact O-CB 3.26Å; E63-K67 WeakPolarHBondContact O-CG 3.44Å; E63-K67 PolarHBondContact O-N 3.27Å
64	E	96.4	Very high	95.4	Very high	107 Å²	107	98.5 Å²	98.5	50%	0.5	50%	0.504	S	S	.	.	H	α-helix	trans	-63.5	-46	172.2	-73.6	178.6	-171.1	0	0	111.1	K60 D61 F62 A68	K60-E64 WeakPolarHBondContact CE-OE1 3.48Å; K60-E64 WeakPolarHBondContact O-CG 3.24Å; K60-E64 PolarHBondContact O-N 2.82Å; D61-E64 PolarHBondContact O-N 3.34Å; F62-E64 VanDerWaalsContact C-N 3.32Å; F62-E64 PolarHBondContact O-N 2.96Å; E64-A68 WeakPolarHBondContact O-CB 3.45Å; E64-A68 PolarHBondContact O-N 3.4Å; E64-A68 VanDerWaalsContact O-N 3.08Å
65	M	96.2	Very high	94.3	Very high	67 Å²	67	100.2 Å²	100.2	33%	0.33	52%	0.517	S	S	.	.	H	α-helix	trans	-65.2	-39.4	175.8	-68.5	-178.8	-167.6	0	0	113.1	D61 F62 A68 G69 I70 F71	D61-M65 WeakPolarHBondContact O-CG 3.38Å; D61-M65 PolarHBondContact O-N 2.94Å; D61-M65 VanDerWaalsContact OD2-CE 3.28Å; D61-M65 WeakPolarHBondContact OD2-CE 3.41Å; F62-M65 PolarHBondContact O-N 3.38Å; M65-A68 PolarHBondContact O-N 2.84Å; M65-G69 PolarHBondContact O-N 3.17Å; M65-I70 HydrophobicContact CB-CD1 4.02Å; M65-I70 HydrophobicContact CG-CD1 4.05Å; M65-I70 PolarHBondContact O-N 2.98Å; M65-F71 HydrophobicContact CB-CE2 3.55Å; M65-F71 HydrophobicContact CB-CZ 3.62Å; M65-F71 HydrophobicContact CG-CZ 4.44Å; M65-F71 HydrophobicContact SD-CZ 3.97Å
66	R	95.1	Very high	94.3	Very high	60 Å²	60	97.9 Å²	97.9	23%	0.226	50%	0.504	C	S	.	.	H	α-helix	trans	-63.5	-48.4	177.4	-172.2	-171.5	68.9	76.4	3.5	110.9	F62 E63 A68 G69 F71 V74 K75	F62-R66 WeakPolarHBondContact O-CB 3.49Å; F62-R66 PolarHBondContact O-N 3.32Å; E63-R66 IonicContact OE1-NE 2.87Å; E63-R66 PolarHBondContact OE1-NE 2.79Å; E63-R66 IonicContact OE2-CZ 2.98Å; E63-R66 VanDerWaalsContact OE2-CZ 3.32Å; E63-R66 IonicContact OE2-NE 2.76Å; E63-R66 PolarHBondContact OE2-NE 3.48Å; E63-R66 IonicContact OE2-NH2 3.21Å; E63-R66 PolarHBondContact OE2-NH2 3.48Å; R66-A68 PolarHBondContact O-N 3.27Å; R66-G69 WeakPolarHBondContact O-CA 3.36Å; R66-G69 PolarHBondContact O-N 3.35Å; R66-F71 HydrophobicContact CB-CD2 4.04Å; R66-F71 HydrophobicContact CB-CE2 4.21Å; R66-V74 HydrophobicContact CG-CG1 3.99Å; R66-K75 WeakPolarHBondContact CD-O 3.46Å; R66-K75 PolarHBondContact NH1-O 3.33Å; R66-K75 PolarHBondContact NH1-OXT 2.96Å
67	K	95.2	Very high	94.1	Very high	156 Å²	156	99.1 Å²	99.1	68%	0.678	52%	0.515	S	S	*	.	H	α-helix	trans	-62.9	-30	176.7	-72.2	171.1	-173.7	173.4	0	112.8	E63 G69	E63-K67 WeakPolarHBondContact O-CB 3.26Å; E63-K67 WeakPolarHBondContact O-CG 3.44Å; E63-K67 PolarHBondContact O-N 3.27Å; K67-G69 PolarHBondContact O-N 3.47Å
68	A	96.2	Very high	93.9	Very high	74 Å²	74	99.6 Å²	99.6	61%	0.612	52%	0.516	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.4	-4.9	172.9	0	0	0	0	0	113.6	E64 M65 R66 I70	E64-A68 WeakPolarHBondContact O-CB 3.45Å; E64-A68 PolarHBondContact O-N 3.4Å; E64-A68 VanDerWaalsContact O-N 3.08Å; M65-A68 PolarHBondContact O-N 2.84Å; R66-A68 PolarHBondContact O-N 3.27Å; A68-I70 VanDerWaalsContact C-N 3.33Å; A68-I70 HydrophobicContact CB-CD1 4.05Å; A68-I70 HydrophobicContact CB-CG1 3.96Å; A68-I70 PolarHBondContact O-N 3.46Å
69	G	94	Very high	93.8	Very high	57 Å²	57	100.2 Å²	100.2	59%	0.588	52%	0.515	S	S	*	.	T	Hydrogen-bonded Turn	trans	72.1	23.8	178	0	0	0	0	0	113.9	M65 R66 K67 F71	M65-G69 PolarHBondContact O-N 3.17Å; R66-G69 WeakPolarHBondContact O-CA 3.36Å; R66-G69 PolarHBondContact O-N 3.35Å; K67-G69 PolarHBondContact O-N 3.47Å; G69-F71 VanDerWaalsContact C-N 3.34Å
70	I	94.7	Very high	93.6	Very high	110 Å²	110	98.8 Å²	98.8	56%	0.564	51%	0.509	S	S	*	.			trans	-71.4	-31.9	-176.3	-61.9	175	0	0	0	111.3	M65 A68	M65-I70 HydrophobicContact CB-CD1 4.02Å; M65-I70 HydrophobicContact CG-CD1 4.05Å; M65-I70 PolarHBondContact O-N 2.98Å; A68-I70 VanDerWaalsContact C-N 3.33Å; A68-I70 HydrophobicContact CB-CD1 4.05Å; A68-I70 HydrophobicContact CB-CG1 3.96Å; A68-I70 PolarHBondContact O-N 3.46Å
71	F	95	Very high	93.4	Very high	65 Å²	65	96.9 Å²	96.9	29%	0.285	51%	0.506	S	S	.	.			trans	-87	139.7	-175.8	-56.9	-58	0	0	0	112.5	F62 M65 R66 G69 V74	F62-F71 HydrophobicContact CD2-CD2 4.43Å; F62-F71 AromaticContact CD2-CE2 3.53Å; F62-F71 HydrophobicContact CD2-CE2 3.53Å; F62-F71 AromaticContact CD2-CZ 3.8Å; F62-F71 HydrophobicContact CD2-CZ 3.8Å; F62-F71 AromaticContact CE2-CD2 3.96Å; F62-F71 HydrophobicContact CE2-CD2 3.96Å; F62-F71 AromaticContact CE2-CE2 3.5Å; F62-F71 HydrophobicContact CE2-CE2 3.5Å; F62-F71 VanDerWaalsContact CE2-CE2 3.5Å; F62-F71 HydrophobicContact CE2-CZ 4.02Å; F62-F71 HydrophobicContact CG-CE2 4.49Å; F62-F71 HydrophobicContact CZ-CE2 4.43Å; M65-F71 HydrophobicContact CB-CE2 3.55Å; M65-F71 HydrophobicContact CB-CZ 3.62Å; M65-F71 HydrophobicContact CG-CZ 4.44Å; M65-F71 HydrophobicContact SD-CZ 3.97Å; R66-F71 HydrophobicContact CB-CD2 4.04Å; R66-F71 HydrophobicContact CB-CE2 4.21Å; G69-F71 VanDerWaalsContact C-N 3.34Å; F71-V74 HydrophobicContact CB-CB 4.4Å
72	Q	94.7	Very high	93.2	Very high	202 Å²	202	100.8 Å²	100.8	94%	0.944	53%	0.526	S	S	*	.	S	Bend	trans	-86	-27.6	170.3	-66.7	-178.5	-11	0	0	112.5
73	S	94.5	Very high	93	Very high	111 Å²	111	103.8 Å²	103.8	78%	0.776	55%	0.546	S	S	*	.	S	Bend	trans	-87.9	-22.2	-174.9	52.8	0	0	0	0	113.9
74	V	85.7	Confident	92.7	Very high	55 Å²	55	107.3 Å²	107.3	33%	0.333	57%	0.568	S	S	.	*			trans	-130	122.7	-177.9	-167.7	0	0	0	0	108.1	F62 R66 F71	F62-V74 HydrophobicContact CZ-CB 4.45Å; F62-V74 HydrophobicContact CZ-CG1 4.17Å; F62-V74 HydrophobicContact CZ-CG2 4.32Å; R66-V74 HydrophobicContact CG-CG1 3.99Å; F71-V74 HydrophobicContact CB-CB 4.4Å
75	K	75.1	Confident	92.4	Very high	224 Å²	224	107.4 Å²	107.4	97%	0.974	57%	0.574	S	S	*	*			trans	-88.9	0	176.9	-66.1	-175.4	179.8	178.6	0	111.9	R66	R66-K75 WeakPolarHBondContact CD-O 3.46Å; R66-K75 PolarHBondContact NH1-O 3.33Å; R66-K75 PolarHBondContact NH1-OXT 2.96Å

Retrieved 75 of 75 residues in 38.9 ms (Link to these results)

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