A0A059RKX9_HUMAN Loading...

NADH-ubiquinone oxidoreductase chain 4L

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Part of the enzyme membrane arm which is embedded in the lipid bilayer and involved in proton translocation.

AlphaFold DB (Q8W7V3), UniProt , Accession A0A059RKX9, Species HUMAN (Homo sapiens, Human), Gene ND4L, Length 98 aa.

						>A0A059RKX9_HUMAN|A0A059RKX9|ND4L
MPLIYMNIMLAFXISLLGMLVYRSHLMSSLLCLEGMMLSLFIMATLMTLNTHSLLANIVPIAMLVFAACEAAVGLALLVSISNTYGLDYVHNLNLLQC
					

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	66.6	Low	89.5	Confident	144 Å²	144	92.5 Å²	92.5	71%	0.709	49%	0.494	S	S	*	.				0	46.9	0	-67.3	-60.4	169.8	0	0	113.2	I4 Y5	M1-I4 HydrophobicContact SD-CD1 3.85Å; M1-Y5 HydrophobicContact CB-CE2 4.36Å; M1-Y5 WeakPolarHBondContact O-CD2 3.18Å
2	P	77.6	Confident	90	Very high	103 Å²	103	89.5 Å²	89.5	67%	0.669	47%	0.474	S	S	*	.	H	α-helix	trans	-73	-33.8	-176.6	30.2	-34.8	0	0	0	113	I4 Y5 M6	P2-I4 PolarHBondContact O-N 3.41Å; P2-Y5 PolarHBondContact O-N 3.23Å; P2-M6 WeakPolarHBondContact O-CG 3.43Å; P2-M6 PolarHBondContact O-N 3.13Å
3	L	89.8	Confident	90.4	Very high	131 Å²	131	85.8 Å²	85.8	69%	0.686	46%	0.464	S	S	*	.	H	α-helix	trans	-65.4	-39.2	-173.9	-141.9	109	0	0	0	112.8	M6 N7	L3-M6 PolarHBondContact O-N 2.89Å; L3-N7 PolarHBondContact O-N 3.1Å; L3-N7 VanDerWaalsContact O-N 3.13Å
4	I	92.1	Very high	90.6	Very high	77 Å²	77	87.1 Å²	87.1	40%	0.395	47%	0.468	S	S	.	.	H	α-helix	trans	-65.5	-43.1	177.6	-62.4	170.1	0	0	0	110	M1 P2 M6 N7 I8 L46	M1-I4 HydrophobicContact SD-CD1 3.85Å; P2-I4 PolarHBondContact O-N 3.41Å; I4-M6 VanDerWaalsContact C-N 3.35Å; I4-M6 PolarHBondContact O-N 2.83Å; I4-N7 PolarHBondContact O-N 3.47Å; I4-I8 HydrophobicContact CG2-CD1 3.72Å; I4-I8 HydrophobicContact CG2-CG1 4.44Å; I4-I8 WeakPolarHBondContact O-CG1 3.49Å; I4-I8 PolarHBondContact O-N 3.41Å; I4-L46 HydrophobicContact CG2-CD1 3.61Å
5	Y	91.3	Very high	90.8	Very high	37 Å²	37	82.5 Å²	82.5	15%	0.145	45%	0.446	C	S	.	.	H	α-helix	trans	-62.7	-40.5	177	-69.7	-52.6	0	0	0	112.5	M1 P2 N7 I8 M9 M43 L46 M47 N50	M1-Y5 HydrophobicContact CB-CE2 4.36Å; M1-Y5 WeakPolarHBondContact O-CD2 3.18Å; P2-Y5 PolarHBondContact O-N 3.23Å; Y5-N7 VanDerWaalsContact C-N 3.34Å; Y5-N7 PolarHBondContact O-N 3.21Å; Y5-I8 PolarHBondContact O-N 2.63Å; Y5-M9 WeakPolarHBondContact O-CB 3.46Å; Y5-M9 VanDerWaalsContact O-CG 3.31Å; Y5-M9 WeakPolarHBondContact O-CG 3.39Å; Y5-M9 PolarHBondContact O-N 3.01Å; Y5-M43 HydrophobicContact CD1-CE 3.89Å; Y5-M43 HydrophobicContact CD1-SD 3.18Å; Y5-M43 WeakPolarHBondContact CD1-SD 3.47Å; Y5-M43 HydrophobicContact CE1-SD 3.53Å; Y5-M43 VanDerWaalsContact CE1-SD 3.53Å; Y5-M43 HydrophobicContact CG-SD 4.22Å; Y5-L46 HydrophobicContact CE1-CB 3.75Å; Y5-L46 HydrophobicContact CE1-CD1 4.3Å; Y5-L46 PolarHBondContact OH-O 3.42Å; Y5-M47 HydrophobicContact CD1-CE 4.06Å; Y5-M47 HydrophobicContact CD2-CE 4.37Å; Y5-M47 HydrophobicContact CE1-CE 3.57Å; Y5-M47 HydrophobicContact CE1-CG 4.08Å; Y5-M47 HydrophobicContact CE1-SD 3.98Å; Y5-M47 HydrophobicContact CE2-CE 3.98Å; Y5-M47 HydrophobicContact CE2-SD 4.26Å; Y5-M47 HydrophobicContact CG-CE 4.41Å; Y5-M47 VanDerWaalsContact CZ-SD 3.55Å; Y5-M47 PolarHBondContact OH-N 3.19Å; Y5-M47 PolarHBondContact OH-SD 3.12Å; Y5-N50 PolarHBondContact OH-ND2 3.42Å
6	M	93.2	Very high	91	Very high	134 Å²	134	81.3 Å²	81.3	66%	0.66	44%	0.438	S	S	*	.	H	α-helix	trans	-59.6	-44	174.1	-67.3	-61.6	-70.1	0	0	111.9	P2 L3 I4 M9 L10	P2-M6 WeakPolarHBondContact O-CG 3.43Å; P2-M6 PolarHBondContact O-N 3.13Å; L3-M6 PolarHBondContact O-N 2.89Å; I4-M6 VanDerWaalsContact C-N 3.35Å; I4-M6 PolarHBondContact O-N 2.83Å; M6-M9 PolarHBondContact O-N 3.01Å; M6-L10 WeakPolarHBondContact O-CB 3.1Å; M6-L10 PolarHBondContact O-N 3.45Å
7	N	94.7	Very high	91.1	Very high	104 Å²	104	82.5 Å²	82.5	56%	0.556	44%	0.444	S	S	*	.	H	α-helix	trans	-65.1	-40.2	178.9	-71	-8	0	0	0	112.5	L3 I4 Y5 L10 A11	L3-N7 PolarHBondContact O-N 3.1Å; L3-N7 VanDerWaalsContact O-N 3.13Å; I4-N7 PolarHBondContact O-N 3.47Å; Y5-N7 VanDerWaalsContact C-N 3.34Å; Y5-N7 PolarHBondContact O-N 3.21Å; N7-L10 WeakPolarHBondContact O-CB 3.44Å; N7-L10 PolarHBondContact O-N 3.42Å; N7-A11 PolarHBondContact O-N 3.17Å
8	I	95	Very high	91.1	Very high	19 Å²	19	79.7 Å²	79.7	10%	0.097	44%	0.437	C	S	.	.	H	α-helix	trans	-69.7	-40.5	178.7	-62.8	161.8	0	0	0	110.7	I4 Y5 L10 A11 F12 S39 I42 M43 L46	I4-I8 HydrophobicContact CG2-CD1 3.72Å; I4-I8 HydrophobicContact CG2-CG1 4.44Å; I4-I8 WeakPolarHBondContact O-CG1 3.49Å; I4-I8 PolarHBondContact O-N 3.41Å; Y5-I8 PolarHBondContact O-N 2.63Å; I8-L10 VanDerWaalsContact C-N 3.26Å; I8-L10 PolarHBondContact O-N 3.18Å; I8-A11 WeakPolarHBondContact O-CB 3.48Å; I8-A11 PolarHBondContact O-N 3.05Å; I8-F12 PolarHBondContact O-N 3.16Å; I8-S39 VanDerWaalsContact CG2-O 3.25Å; I8-S39 WeakPolarHBondContact CG2-O 3.48Å; I8-I42 HydrophobicContact CD1-CB 4.43Å; I8-I42 HydrophobicContact CD1-CG2 3.58Å; I8-I42 HydrophobicContact CG1-CG2 4.27Å; I8-M43 HydrophobicContact CB-CE 3.82Å; I8-M43 HydrophobicContact CG2-CB 4.15Å; I8-M43 HydrophobicContact CG2-CE 3.72Å; I8-L46 HydrophobicContact CD1-CD1 3.3Å
9	M	93.7	Very high	91	Very high	109 Å²	109	77.7 Å²	77.7	54%	0.537	43%	0.425	S	S	.	.	H	α-helix	trans	-61.3	-37.5	173.3	-72.8	-57.9	-66.1	0	0	111.7	Y5 M6 F12 X13 M43	Y5-M9 WeakPolarHBondContact O-CB 3.46Å; Y5-M9 VanDerWaalsContact O-CG 3.31Å; Y5-M9 WeakPolarHBondContact O-CG 3.39Å; Y5-M9 PolarHBondContact O-N 3.01Å; M6-M9 PolarHBondContact O-N 3.01Å; M9-F12 PolarHBondContact O-N 2.82Å; M9-A13 WeakPolarHBondContact O-CB 3.46Å; M9-A13 PolarHBondContact O-N 3.43Å; M9-M43 HydrophobicContact CG-CE 3.68Å; M9-M43 HydrophobicContact SD-CE 3.67Å
10	L	95.4	Very high	90.8	Very high	111 Å²	111	78.8 Å²	78.8	58%	0.581	43%	0.43	S	S	*	.	H	α-helix	trans	-66.5	-41.3	175.2	-156.3	118.1	0	0	0	111.4	M6 N7 I8 F12 X13 I14	M6-L10 WeakPolarHBondContact O-CB 3.1Å; M6-L10 PolarHBondContact O-N 3.45Å; N7-L10 WeakPolarHBondContact O-CB 3.44Å; N7-L10 PolarHBondContact O-N 3.42Å; I8-L10 VanDerWaalsContact C-N 3.26Å; I8-L10 PolarHBondContact O-N 3.18Å; L10-F12 PolarHBondContact O-N 3.37Å; L10-A13 PolarHBondContact O-N 2.97Å; L10-I14 HydrophobicContact CD2-CD1 3.63Å; L10-I14 HydrophobicContact CG-CD1 4.32Å; L10-I14 WeakPolarHBondContact O-CD1 3.5Å; L10-I14 VanDerWaalsContact O-CG1 3.26Å; L10-I14 WeakPolarHBondContact O-CG1 3.4Å; L10-I14 PolarHBondContact O-N 3.4Å
11	A	95.1	Very high	90.7	Very high	48 Å²	48	79.5 Å²	79.5	40%	0.397	44%	0.437	S	S	.	.	H	α-helix	trans	-62.1	-41	174.2	0	0	0	0	0	112.4	N7 I8 I14 S15	N7-A11 PolarHBondContact O-N 3.17Å; I8-A11 WeakPolarHBondContact O-CB 3.48Å; I8-A11 PolarHBondContact O-N 3.05Å; A11-I14 PolarHBondContact O-N 3.16Å; A11-S15 PolarHBondContact O-N 3.02Å; A11-S15 PolarHBondContact O-OG 3.42Å
12	F	95.4	Very high	91	Very high	57 Å²	57	80.1 Å²	80.1	25%	0.25	43%	0.432	C	S	.	.	H	α-helix	trans	-61.4	-45.2	172.3	-178.8	-97.9	0	0	0	111.5	I8 M9 L10 I14 S15 L16 M36 S39 L40	I8-F12 PolarHBondContact O-N 3.16Å; M9-F12 PolarHBondContact O-N 2.82Å; L10-F12 PolarHBondContact O-N 3.37Å; F12-I14 PolarHBondContact O-N 3.28Å; F12-S15 WeakPolarHBondContact CA-OG 3.37Å; F12-S15 PolarHBondContact O-N 3.2Å; F12-S15 PolarHBondContact O-OG 3.13Å; F12-L16 HydrophobicContact CE1-CD1 4.32Å; F12-L16 HydrophobicContact CZ-CD1 4.31Å; F12-L16 VanDerWaalsContact O-CB 3.31Å; F12-L16 WeakPolarHBondContact O-CB 3.48Å; F12-L16 PolarHBondContact O-N 2.97Å; F12-M36 HydrophobicContact CD2-CB 4.17Å; F12-M36 HydrophobicContact CD2-CG 4.25Å; F12-M36 HydrophobicContact CE2-CB 4Å; F12-M36 HydrophobicContact CE2-CG 4.13Å; F12-M36 HydrophobicContact CE2-SD 4.34Å; F12-S39 WeakPolarHBondContact CB-OG 3.49Å; F12-S39 WeakPolarHBondContact CD2-OG 3.43Å; F12-L40 HydrophobicContact CD2-CD2 4.31Å; F12-L40 HydrophobicContact CD2-CG 4.09Å; F12-L40 HydrophobicContact CE2-CD1 3.98Å; F12-L40 HydrophobicContact CE2-CD2 4.2Å; F12-L40 HydrophobicContact CE2-CG 3.97Å
13	X	94.8	Very high	90.7	Very high	42 Å²	42	84 Å²	84	35%	0.347	43%	0.434	S	S	.	.	H	α-helix	trans	-63.4	-40	178.6	0	0	0	0	0	112.6	M9 L10 L16 L17	M9-A13 WeakPolarHBondContact O-CB 3.46Å; M9-A13 PolarHBondContact O-N 3.43Å; L10-A13 PolarHBondContact O-N 2.97Å; A13-L16 PolarHBondContact O-N 3.43Å; A13-L17 WeakPolarHBondContact O-CB 3.3Å; A13-L17 VanDerWaalsContact O-CG 3.27Å; A13-L17 WeakPolarHBondContact O-CG 3.47Å; A13-L17 PolarHBondContact O-N 3.01Å
14	I	94.4	Very high	89.7	Confident	103 Å²	103	80.8 Å²	80.8	53%	0.528	42%	0.422	S	S	.	.	H	α-helix	trans	-67.1	-43	178.1	-66.9	162.4	0	0	0	111.1	L10 A11 F12 L17 G18	L10-I14 HydrophobicContact CD2-CD1 3.63Å; L10-I14 HydrophobicContact CG-CD1 4.32Å; L10-I14 WeakPolarHBondContact O-CD1 3.5Å; L10-I14 VanDerWaalsContact O-CG1 3.26Å; L10-I14 WeakPolarHBondContact O-CG1 3.4Å; L10-I14 PolarHBondContact O-N 3.4Å; A11-I14 PolarHBondContact O-N 3.16Å; F12-I14 PolarHBondContact O-N 3.28Å; I14-L17 PolarHBondContact O-N 3.44Å; I14-G18 PolarHBondContact O-N 3.19Å
15	S	93.3	Very high	89.2	Confident	18 Å²	18	81 Å²	81	13%	0.126	42%	0.421	C	S	.	.	H	α-helix	trans	-67.6	-38.1	177.4	49.6	0	0	0	0	112.2	A11 F12 G18 M19 M36	A11-S15 PolarHBondContact O-N 3.02Å; A11-S15 PolarHBondContact O-OG 3.42Å; F12-S15 WeakPolarHBondContact CA-OG 3.37Å; F12-S15 PolarHBondContact O-N 3.2Å; F12-S15 PolarHBondContact O-OG 3.13Å; S15-G18 PolarHBondContact O-N 2.96Å; S15-M19 PolarHBondContact O-N 3.39Å; S15-M36 WeakPolarHBondContact OG-CG 3.43Å
16	L	93.6	Very high	88.7	Confident	63 Å²	63	81 Å²	81	33%	0.33	42%	0.423	S	S	.	.	H	α-helix	trans	-60.6	-47.7	171.2	-174.3	104.6	0	0	0	111.8	F12 X13 G18 M19 L20 M36	F12-L16 HydrophobicContact CE1-CD1 4.32Å; F12-L16 HydrophobicContact CZ-CD1 4.31Å; F12-L16 VanDerWaalsContact O-CB 3.31Å; F12-L16 WeakPolarHBondContact O-CB 3.48Å; F12-L16 PolarHBondContact O-N 2.97Å; A13-L16 PolarHBondContact O-N 3.43Å; L16-G18 VanDerWaalsContact C-N 3.29Å; L16-G18 PolarHBondContact O-N 3.1Å; L16-M19 PolarHBondContact O-N 3.23Å; L16-M19 VanDerWaalsContact O-N 3.17Å; L16-L20 HydrophobicContact CD2-CD1 4.06Å; L16-L20 HydrophobicContact CG-CD1 4.25Å; L16-L20 WeakPolarHBondContact O-CG 3.37Å; L16-L20 PolarHBondContact O-N 3.43Å; L16-M36 HydrophobicContact CB-SD 3.98Å; L16-M36 HydrophobicContact CD1-SD 3.95Å; L16-M36 HydrophobicContact CG-SD 4.46Å
17	L	92.8	Very high	88.4	Confident	103 Å²	103	78.3 Å²	78.3	54%	0.539	41%	0.41	S	S	.	.	H	α-helix	trans	-60.2	-40.4	175.4	-75.5	169.3	0	0	0	111.6	X13 I14 M19 L20 V21	A13-L17 WeakPolarHBondContact O-CB 3.3Å; A13-L17 VanDerWaalsContact O-CG 3.27Å; A13-L17 WeakPolarHBondContact O-CG 3.47Å; A13-L17 PolarHBondContact O-N 3.01Å; I14-L17 PolarHBondContact O-N 3.44Å; L17-M19 VanDerWaalsContact C-N 3.3Å; L17-M19 PolarHBondContact O-N 2.9Å; L17-L20 PolarHBondContact O-N 3.02Å; L17-V21 WeakPolarHBondContact O-CG2 3.41Å; L17-V21 PolarHBondContact O-N 2.96Å
18	G	90.3	Very high	88	Confident	31 Å²	31	75.3 Å²	75.3	32%	0.32	40%	0.398	S	S	.	.	H	α-helix	trans	-61.4	-36.1	175.5	0	0	0	0	0	113.4	I14 S15 L16	I14-G18 PolarHBondContact O-N 3.19Å; S15-G18 PolarHBondContact O-N 2.96Å; L16-G18 VanDerWaalsContact C-N 3.29Å; L16-G18 PolarHBondContact O-N 3.1Å
19	M	89	Confident	87.7	Confident	43 Å²	43	75.3 Å²	75.3	21%	0.212	40%	0.399	C	S	.	.	H	α-helix	trans	-73.2	-42.4	176.2	-173.3	-86.5	-73	0	0	112.3	S15 L16 L17 V21 C32 M36	S15-M19 PolarHBondContact O-N 3.39Å; L16-M19 PolarHBondContact O-N 3.23Å; L16-M19 VanDerWaalsContact O-N 3.17Å; L17-M19 VanDerWaalsContact C-N 3.3Å; L17-M19 PolarHBondContact O-N 2.9Å; M19-V21 VanDerWaalsContact C-N 3.32Å; M19-V21 PolarHBondContact O-N 3.06Å; M19-C32 HydrophobicContact CB-CB 4.11Å; M19-M36 HydrophobicContact CB-CE 4.16Å; M19-M36 HydrophobicContact CE-CE 4.09Å; M19-M36 HydrophobicContact CG-CE 4.21Å
20	L	88.8	Confident	87.4	Confident	99 Å²	99	71.5 Å²	71.5	52%	0.518	38%	0.381	S	S	.	.	H	α-helix	trans	-66.2	-34.2	178.2	-69.6	172	0	0	0	112.5	L16 L17 Y22	L16-L20 HydrophobicContact CD2-CD1 4.06Å; L16-L20 HydrophobicContact CG-CD1 4.25Å; L16-L20 WeakPolarHBondContact O-CG 3.37Å; L16-L20 PolarHBondContact O-N 3.43Å; L17-L20 PolarHBondContact O-N 3.02Å; L20-Y22 VanDerWaalsContact C-N 3.26Å; L20-Y22 PolarHBondContact O-N 3.35Å
21	V	88.1	Confident	87.2	Confident	94 Å²	94	71.2 Å²	71.2	57%	0.57	38%	0.379	S	S	*	.	S	Bend	trans	-82.6	78.2	172.7	-176.8	0	0	0	0	108.4	L17 M19 R23	L17-V21 WeakPolarHBondContact O-CG2 3.41Å; L17-V21 PolarHBondContact O-N 2.96Å; M19-V21 VanDerWaalsContact C-N 3.32Å; M19-V21 PolarHBondContact O-N 3.06Å; V21-R23 PolarHBondContact O-N 3.29Å
22	Y	71.9	Confident	87	Confident	157 Å²	157	70.5 Å²	70.5	62%	0.616	37%	0.371	S	S	*	.			trans	-55.8	110.2	176.3	-68.2	-72.6	0	0	0	110.6	L20	L20-Y22 VanDerWaalsContact C-N 3.26Å; L20-Y22 PolarHBondContact O-N 3.35Å
23	R	71.1	Confident	86.8	Confident	184 Å²	184	70.9 Å²	70.9	69%	0.694	38%	0.376	S	S	*	.			trans	-78.8	166.2	164.4	-68.5	-82.7	-163.9	119.1	4.4	108.9	V21 H25	V21-R23 PolarHBondContact O-N 3.29Å; R23-H25 PolarHBondContact O-N 2.87Å; R23-H25 VanDerWaalsContact O-N 3.11Å
24	S	69.9	Low	86.7	Confident	64 Å²	64	73.6 Å²	73.6	45%	0.448	38%	0.381	S	S	.	.	S	Bend	trans	-53.4	-32.8	179.8	52.5	0	0	0	0	113.7	Y89 V90	S24-Y89 WeakPolarHBondContact O-CA 3Å; S24-V90 PolarHBondContact O-N 3.38Å; S24-V90 VanDerWaalsContact O-N 3.11Å
25	H	81.9	Confident	86.6	Confident	82 Å²	82	70.2 Å²	70.2	38%	0.38	37%	0.371	S	S	.	.	B	Isolated β-bridge	trans	-99	125	-174	-61.4	-76.7	0	0	0	113.6	R23 M27 S28 Y89	R23-H25 PolarHBondContact O-N 2.87Å; R23-H25 VanDerWaalsContact O-N 3.11Å; H25-M27 VanDerWaalsContact C-N 3.27Å; H25-M27 PolarHBondContact O-N 3.26Å; H25-S28 PolarHBondContact O-N 3.35Å; H25-S28 PolarHBondContact O-OG 3.07Å; H25-Y89 AromaticContact CE1-CE1 3.21Å; H25-Y89 WeakPolarHBondContact CE1-CE1 3.41Å; H25-Y89 AromaticContact CE1-CZ 3.73Å; H25-Y89 AromaticContact ND1-CE1 3.71Å; H25-Y89 AromaticContact NE2-CE1 3.65Å
26	L	81.2	Confident	86.6	Confident	35 Å²	35	70.1 Å²	70.1	18%	0.183	37%	0.369	C	S	.	.	H	α-helix	trans	-62.6	-30.7	175.4	-157	101.8	0	0	0	112.9	S28 S29 L30 L78 I81 D88 V90	L26-S28 PolarHBondContact O-N 3.49Å; L26-S29 PolarHBondContact O-N 3.35Å; L26-S29 PolarHBondContact O-OG 3.47Å; L26-L30 HydrophobicContact CD2-CD1 4.47Å; L26-L30 PolarHBondContact O-N 3.49Å; L26-L30 VanDerWaalsContact O-N 3.15Å; L26-L78 HydrophobicContact CB-CD1 4.12Å; L26-L78 HydrophobicContact CD2-CB 3.92Å; L26-L78 HydrophobicContact CD2-CD1 3.8Å; L26-L78 HydrophobicContact CD2-CG 3.93Å; L26-L78 HydrophobicContact CG-CD1 4.49Å; L26-I81 HydrophobicContact CD2-CD1 4.32Å; L26-D88 PolarHBondContact N-O 3.3Å; L26-V90 HydrophobicContact CB-CG2 4.3Å; L26-V90 HydrophobicContact CD1-CG2 3.87Å
27	M	85.6	Confident	86.6	Confident	78 Å²	78	68.8 Å²	68.8	38%	0.384	36%	0.362	S	S	.	.	H	α-helix	trans	-56.7	-38.1	175.3	-75.8	-59.6	-66.8	0	0	112.5	H25 L30 L31 L75 L78	H25-M27 VanDerWaalsContact C-N 3.27Å; H25-M27 PolarHBondContact O-N 3.26Å; M27-L30 PolarHBondContact O-N 3.49Å; M27-L31 WeakPolarHBondContact O-CG 3.48Å; M27-L31 PolarHBondContact O-N 3.25Å; M27-L31 VanDerWaalsContact O-N 3.13Å; M27-L75 HydrophobicContact CE-CD2 4.47Å; M27-L75 HydrophobicContact SD-CD2 4.27Å; M27-L78 HydrophobicContact CB-CD1 4.48Å; M27-L78 HydrophobicContact CG-CD1 3.65Å; M27-L78 HydrophobicContact SD-CD1 3.18Å; M27-L78 WeakPolarHBondContact SD-CD1 3.22Å; M27-L78 HydrophobicContact SD-CD2 4.23Å; M27-L78 HydrophobicContact SD-CG 4.35Å
28	S	86.4	Confident	86.6	Confident	42 Å²	42	68.9 Å²	68.9	29%	0.294	36%	0.362	S	S	.	.	H	α-helix	trans	-70.5	-34.1	-177.6	67.6	0	0	0	0	112.6	H25 L26 C32	H25-S28 PolarHBondContact O-N 3.35Å; H25-S28 PolarHBondContact O-OG 3.07Å; L26-S28 PolarHBondContact O-N 3.49Å; S28-C32 PolarHBondContact O-N 3.41Å; S28-C32 VanDerWaalsContact O-N 3.17Å; S28-C32 PolarHBondContact O-SG 3.47Å; S28-C32 VanDerWaalsContact O-SG 3.34Å
29	S	88	Confident	86.9	Confident	19 Å²	19	67.8 Å²	67.8	13%	0.133	35%	0.35	C	S	.	.	H	α-helix	trans	-72.6	-35.3	175.1	57.5	0	0	0	0	111.9	L26 C32 L33	L26-S29 PolarHBondContact O-N 3.35Å; L26-S29 PolarHBondContact O-OG 3.47Å; S29-C32 WeakPolarHBondContact O-CB 3.18Å; S29-C32 PolarHBondContact O-N 3.11Å; S29-L33 PolarHBondContact O-N 2.94Å
30	L	89.1	Confident	87.1	Confident	29 Å²	29	69.1 Å²	69.1	15%	0.152	36%	0.357	C	S	.	.	H	α-helix	trans	-61.1	-44	173	-71.3	176.7	0	0	0	111.8	L26 M27 C32 L33 E34 L75 L78	L26-L30 HydrophobicContact CD2-CD1 4.47Å; L26-L30 PolarHBondContact O-N 3.49Å; L26-L30 VanDerWaalsContact O-N 3.15Å; M27-L30 PolarHBondContact O-N 3.49Å; L30-C32 VanDerWaalsContact C-N 3.32Å; L30-C32 PolarHBondContact O-N 2.91Å; L30-L33 WeakPolarHBondContact O-CA 3.34Å; L30-L33 WeakPolarHBondContact O-CB 3.21Å; L30-L33 PolarHBondContact O-N 2.99Å; L30-L33 VanDerWaalsContact O-N 3.07Å; L30-E34 PolarHBondContact O-N 3.48Å; L30-L75 HydrophobicContact CD1-CD2 4.05Å; L30-L75 HydrophobicContact CD1-CG 4.5Å; L30-L78 HydrophobicContact CD1-CD1 3.77Å
31	L	89.8	Confident	87.4	Confident	105 Å²	105	67.1 Å²	67.1	55%	0.55	34%	0.344	S	S	.	.	H	α-helix	trans	-62.7	-37.6	175.2	-71.1	172.9	0	0	0	112.5	M27 L33 E34 G35	M27-L31 WeakPolarHBondContact O-CG 3.48Å; M27-L31 PolarHBondContact O-N 3.25Å; M27-L31 VanDerWaalsContact O-N 3.13Å; L31-L33 VanDerWaalsContact C-N 3.28Å; L31-L33 PolarHBondContact O-N 3.34Å; L31-E34 PolarHBondContact O-N 3.3Å; L31-G35 PolarHBondContact O-N 3.09Å
32	C	91.6	Very high	87.6	Confident	33 Å²	33	65.9 Å²	65.9	22%	0.223	33%	0.334	C	S	.	.	H	α-helix	trans	-63.5	-36.1	173	-69.2	0	0	0	0	111.8	M19 S28 S29 L30 G35 M36	M19-C32 HydrophobicContact CB-CB 4.11Å; S28-C32 PolarHBondContact O-N 3.41Å; S28-C32 VanDerWaalsContact O-N 3.17Å; S28-C32 PolarHBondContact O-SG 3.47Å; S28-C32 VanDerWaalsContact O-SG 3.34Å; S29-C32 WeakPolarHBondContact O-CB 3.18Å; S29-C32 PolarHBondContact O-N 3.11Å; L30-C32 VanDerWaalsContact C-N 3.32Å; L30-C32 PolarHBondContact O-N 2.91Å; C32-G35 PolarHBondContact O-N 3.22Å; C32-M36 WeakPolarHBondContact O-CG 3.48Å; C32-M36 PolarHBondContact O-N 3.18Å
33	L	90.9	Very high	88.6	Confident	65 Å²	65	59.8 Å²	59.8	34%	0.34	31%	0.311	S	S	.	.	H	α-helix	trans	-66.8	-44.3	176.3	-148.2	162.6	0	0	0	111.5	S29 L30 L31 G35 M36 M37	S29-L33 PolarHBondContact O-N 2.94Å; L30-L33 WeakPolarHBondContact O-CA 3.34Å; L30-L33 WeakPolarHBondContact O-CB 3.21Å; L30-L33 PolarHBondContact O-N 2.99Å; L30-L33 VanDerWaalsContact O-N 3.07Å; L31-L33 VanDerWaalsContact C-N 3.28Å; L31-L33 PolarHBondContact O-N 3.34Å; L33-G35 VanDerWaalsContact C-N 3.3Å; L33-G35 PolarHBondContact O-N 3.4Å; L33-M36 HydrophobicContact CB-CE 4.21Å; L33-M36 HydrophobicContact CG-CE 3.93Å; L33-M36 WeakPolarHBondContact O-CB 3.22Å; L33-M36 PolarHBondContact O-N 3.18Å; L33-M37 HydrophobicContact CD2-CG 4.14Å; L33-M37 WeakPolarHBondContact O-CG 3.33Å; L33-M37 PolarHBondContact O-N 3.49Å
34	E	92.2	Very high	89.6	Confident	99 Å²	99	52.3 Å²	52.3	46%	0.463	29%	0.289	S	S	.	.	H	α-helix	trans	-59.4	-40.6	171.8	-70.2	-175.7	169	0	0	112.1	L30 L31 M36 M37 L38	L30-E34 PolarHBondContact O-N 3.48Å; L31-E34 PolarHBondContact O-N 3.3Å; E34-M36 PolarHBondContact O-N 2.98Å; E34-M37 PolarHBondContact O-N 3.01Å; E34-L38 WeakPolarHBondContact O-CB 3.43Å; E34-L38 PolarHBondContact O-N 2.82Å
35	G	92	Very high	90.6	Very high	31 Å²	31	50.9 Å²	50.9	32%	0.32	28%	0.277	S	S	.	.	H	α-helix	trans	-61	-40.8	174.5	0	0	0	0	0	113.4	L31 C32 L33 L38 S39	L31-G35 PolarHBondContact O-N 3.09Å; C32-G35 PolarHBondContact O-N 3.22Å; L33-G35 VanDerWaalsContact C-N 3.3Å; L33-G35 PolarHBondContact O-N 3.4Å; G35-L38 PolarHBondContact O-N 3.11Å; G35-S39 PolarHBondContact O-N 3.13Å; G35-S39 VanDerWaalsContact O-N 3.07Å
36	M	93.9	Very high	91	Very high	16 Å²	16	49 Å²	49	8%	0.079	27%	0.27	C	S	.	.	H	α-helix	trans	-61.8	-48.5	173.7	-73.2	-172.2	-67.2	0	0	111.1	F12 S15 L16 M19 C32 L33 E34 L38 S39 L40	F12-M36 HydrophobicContact CD2-CB 4.17Å; F12-M36 HydrophobicContact CD2-CG 4.25Å; F12-M36 HydrophobicContact CE2-CB 4Å; F12-M36 HydrophobicContact CE2-CG 4.13Å; F12-M36 HydrophobicContact CE2-SD 4.34Å; S15-M36 WeakPolarHBondContact OG-CG 3.43Å; L16-M36 HydrophobicContact CB-SD 3.98Å; L16-M36 HydrophobicContact CD1-SD 3.95Å; L16-M36 HydrophobicContact CG-SD 4.46Å; M19-M36 HydrophobicContact CB-CE 4.16Å; M19-M36 HydrophobicContact CE-CE 4.09Å; M19-M36 HydrophobicContact CG-CE 4.21Å; C32-M36 WeakPolarHBondContact O-CG 3.48Å; C32-M36 PolarHBondContact O-N 3.18Å; L33-M36 HydrophobicContact CB-CE 4.21Å; L33-M36 HydrophobicContact CG-CE 3.93Å; L33-M36 WeakPolarHBondContact O-CB 3.22Å; L33-M36 PolarHBondContact O-N 3.18Å; E34-M36 PolarHBondContact O-N 2.98Å; M36-L38 VanDerWaalsContact C-N 3.32Å; M36-L38 PolarHBondContact O-N 2.96Å; M36-S39 PolarHBondContact O-N 3.42Å; M36-S39 PolarHBondContact O-OG 3.41Å; M36-L40 PolarHBondContact O-N 3.15Å; M36-L40 VanDerWaalsContact O-N 3.07Å
37	M	94.6	Very high	91.4	Very high	36 Å²	36	51.6 Å²	51.6	18%	0.177	28%	0.282	C	S	.	.	H	α-helix	trans	-62.1	-39	-179.8	-64.8	-56.2	-78.8	0	0	112.3	L33 E34 L40 F41 M63 A67	L33-M37 HydrophobicContact CD2-CG 4.14Å; L33-M37 WeakPolarHBondContact O-CG 3.33Å; L33-M37 PolarHBondContact O-N 3.49Å; E34-M37 PolarHBondContact O-N 3.01Å; M37-L40 PolarHBondContact O-N 3.26Å; M37-L40 HydrophobicContact SD-CD1 4.45Å; M37-F41 WeakPolarHBondContact O-CB 3.29Å; M37-F41 PolarHBondContact O-N 3.18Å; M37-M63 HydrophobicContact CE-CE 4.44Å; M37-A67 HydrophobicContact CB-CB 3.99Å; M37-A67 HydrophobicContact CE-CB 3.35Å; M37-A67 HydrophobicContact CG-CB 3.95Å; M37-A67 HydrophobicContact SD-CB 4.5Å
38	L	93.3	Very high	91.6	Very high	105 Å²	105	48.5 Å²	48.5	55%	0.55	27%	0.268	S	S	.	.	H	α-helix	trans	-65.2	-41.9	176.3	-172.6	143.3	0	0	0	112	E34 G35 M36 L40 F41 I42	E34-L38 WeakPolarHBondContact O-CB 3.43Å; E34-L38 PolarHBondContact O-N 2.82Å; G35-L38 PolarHBondContact O-N 3.11Å; M36-L38 VanDerWaalsContact C-N 3.32Å; M36-L38 PolarHBondContact O-N 2.96Å; L38-L40 VanDerWaalsContact C-N 3.35Å; L38-L40 PolarHBondContact O-N 3Å; L38-F41 WeakPolarHBondContact O-CB 3.41Å; L38-F41 PolarHBondContact O-N 3.33Å; L38-I42 HydrophobicContact CD2-CD1 3.56Å; L38-I42 HydrophobicContact CD2-CG1 4.37Å; L38-I42 HydrophobicContact CG-CD1 4.46Å; L38-I42 WeakPolarHBondContact O-CG1 3.49Å; L38-I42 PolarHBondContact O-N 3.41Å
39	S	95.1	Very high	91.6	Very high	8 Å²	8	51.6 Å²	51.6	6%	0.056	28%	0.281	C	S	.	.	H	α-helix	trans	-64.5	-38.5	176.8	70.5	0	0	0	0	112.5	I8 F12 G35 M36 I42 M43	I8-S39 VanDerWaalsContact CG2-O 3.25Å; I8-S39 WeakPolarHBondContact CG2-O 3.48Å; F12-S39 WeakPolarHBondContact CB-OG 3.49Å; F12-S39 WeakPolarHBondContact CD2-OG 3.43Å; G35-S39 PolarHBondContact O-N 3.13Å; G35-S39 VanDerWaalsContact O-N 3.07Å; M36-S39 PolarHBondContact O-N 3.42Å; M36-S39 PolarHBondContact O-OG 3.41Å; S39-I42 PolarHBondContact O-N 3.17Å; S39-M43 WeakPolarHBondContact O-CB 3.47Å; S39-M43 PolarHBondContact O-N 3.04Å
40	L	93.3	Very high	91.6	Very high	70 Å²	70	54.7 Å²	54.7	37%	0.366	30%	0.295	S	S	.	.	H	α-helix	trans	-65.8	-39	173.8	-72.4	173	0	0	0	112.1	F12 M36 M37 L38 M43 A44	F12-L40 HydrophobicContact CD2-CD2 4.31Å; F12-L40 HydrophobicContact CD2-CG 4.09Å; F12-L40 HydrophobicContact CE2-CD1 3.98Å; F12-L40 HydrophobicContact CE2-CD2 4.2Å; F12-L40 HydrophobicContact CE2-CG 3.97Å; M36-L40 PolarHBondContact O-N 3.15Å; M36-L40 VanDerWaalsContact O-N 3.07Å; M37-L40 PolarHBondContact O-N 3.26Å; M37-L40 HydrophobicContact SD-CD1 4.45Å; L38-L40 VanDerWaalsContact C-N 3.35Å; L38-L40 PolarHBondContact O-N 3Å; L40-M43 PolarHBondContact O-N 3.25Å; L40-A44 WeakPolarHBondContact O-CB 3.37Å; L40-A44 PolarHBondContact O-N 3.26Å
41	F	94.6	Very high	91.4	Very high	58 Å²	58	57.8 Å²	57.8	25%	0.254	32%	0.316	S	S	.	.	H	α-helix	trans	-61.5	-47.3	175	175	-102.1	0	0	0	112	M37 L38 M43 A44 T45 P60 L64	M37-F41 WeakPolarHBondContact O-CB 3.29Å; M37-F41 PolarHBondContact O-N 3.18Å; L38-F41 WeakPolarHBondContact O-CB 3.41Å; L38-F41 PolarHBondContact O-N 3.33Å; F41-M43 VanDerWaalsContact C-N 3.33Å; F41-M43 PolarHBondContact O-N 2.72Å; F41-A44 PolarHBondContact O-N 2.99Å; F41-T45 HydrophobicContact CD1-CG2 4.41Å; F41-T45 HydrophobicContact CD2-CG2 4.18Å; F41-T45 HydrophobicContact CE1-CG2 3.97Å; F41-T45 HydrophobicContact CE2-CG2 3.73Å; F41-T45 HydrophobicContact CZ-CG2 3.62Å; F41-T45 WeakPolarHBondContact O-CG2 3.46Å; F41-T45 PolarHBondContact O-N 3.38Å; F41-T45 PolarHBondContact O-OG1 3.47Å; F41-P60 HydrophobicContact CD2-CB 3.64Å; F41-P60 WeakPolarHBondContact CD2-O 3.17Å; F41-P60 HydrophobicContact CE2-CB 3.48Å; F41-P60 VanDerWaalsContact CE2-CB 3.48Å; F41-L64 HydrophobicContact CB-CD2 4.4Å; F41-L64 HydrophobicContact CD1-CD1 4.41Å; F41-L64 HydrophobicContact CD2-CD1 3.49Å; F41-L64 VanDerWaalsContact CD2-CD1 3.49Å; F41-L64 HydrophobicContact CD2-CD2 4.18Å; F41-L64 HydrophobicContact CD2-CG 3.52Å; F41-L64 HydrophobicContact CE1-CD1 4.21Å; F41-L64 HydrophobicContact CE2-CD1 3.24Å; F41-L64 HydrophobicContact CE2-CG 3.81Å; F41-L64 HydrophobicContact CG-CD1 4.07Å; F41-L64 HydrophobicContact CG-CD2 4.21Å; F41-L64 HydrophobicContact CG-CG 4.05Å; F41-L64 HydrophobicContact CZ-CD1 3.64Å
42	I	93.9	Very high	91.1	Very high	67 Å²	67	60.7 Å²	60.7	34%	0.344	33%	0.326	S	S	.	.	H	α-helix	trans	-63.9	-40.5	177.7	-61.2	171.8	0	0	0	110.5	I8 L38 S39 T45 L46	I8-I42 HydrophobicContact CD1-CB 4.43Å; I8-I42 HydrophobicContact CD1-CG2 3.58Å; I8-I42 HydrophobicContact CG1-CG2 4.27Å; L38-I42 HydrophobicContact CD2-CD1 3.56Å; L38-I42 HydrophobicContact CD2-CG1 4.37Å; L38-I42 HydrophobicContact CG-CD1 4.46Å; L38-I42 WeakPolarHBondContact O-CG1 3.49Å; L38-I42 PolarHBondContact O-N 3.41Å; S39-I42 PolarHBondContact O-N 3.17Å; I42-T45 WeakPolarHBondContact CA-OG1 3.47Å; I42-T45 PolarHBondContact O-OG1 2.91Å; I42-L46 HydrophobicContact CG2-CD1 3.91Å; I42-L46 HydrophobicContact CG2-CG 4.38Å; I42-L46 WeakPolarHBondContact O-CB 3.35Å; I42-L46 VanDerWaalsContact O-CG 3.28Å; I42-L46 WeakPolarHBondContact O-CG 3.45Å; I42-L46 PolarHBondContact O-N 3.3Å
43	M	92.4	Very high	90.6	Very high	29 Å²	29	61.1 Å²	61.1	14%	0.143	33%	0.329	C	S	.	.	H	α-helix	trans	-59.6	-49.9	175.8	-176.7	63.2	69	0	0	111.5	Y5 I8 M9 S39 L40 F41 L46 M47	Y5-M43 HydrophobicContact CD1-CE 3.89Å; Y5-M43 HydrophobicContact CD1-SD 3.18Å; Y5-M43 WeakPolarHBondContact CD1-SD 3.47Å; Y5-M43 HydrophobicContact CE1-SD 3.53Å; Y5-M43 VanDerWaalsContact CE1-SD 3.53Å; Y5-M43 HydrophobicContact CG-SD 4.22Å; I8-M43 HydrophobicContact CB-CE 3.82Å; I8-M43 HydrophobicContact CG2-CB 4.15Å; I8-M43 HydrophobicContact CG2-CE 3.72Å; M9-M43 HydrophobicContact CG-CE 3.68Å; M9-M43 HydrophobicContact SD-CE 3.67Å; S39-M43 WeakPolarHBondContact O-CB 3.47Å; S39-M43 PolarHBondContact O-N 3.04Å; L40-M43 PolarHBondContact O-N 3.25Å; F41-M43 VanDerWaalsContact C-N 3.33Å; F41-M43 PolarHBondContact O-N 2.72Å; M43-L46 PolarHBondContact O-N 2.98Å; M43-M47 WeakPolarHBondContact O-CG 3.44Å; M43-M47 PolarHBondContact O-N 2.96Å; M43-M47 VanDerWaalsContact O-N 3.08Å; M43-M47 HydrophobicContact SD-CE 4.21Å
44	A	90.9	Very high	90	Very high	28 Å²	28	64.9 Å²	64.9	23%	0.231	35%	0.349	C	S	.	.	H	α-helix	trans	-63.4	-47.7	-178.7	0	0	0	0	0	111.5	L40 F41 L46 M47 T48 P60	L40-A44 WeakPolarHBondContact O-CB 3.37Å; L40-A44 PolarHBondContact O-N 3.26Å; F41-A44 PolarHBondContact O-N 2.99Å; A44-L46 PolarHBondContact O-N 3.15Å; A44-M47 WeakPolarHBondContact O-CB 3.21Å; A44-M47 PolarHBondContact O-N 3.12Å; A44-M47 VanDerWaalsContact O-N 3.17Å; A44-T48 WeakPolarHBondContact O-CG2 3.36Å; A44-T48 PolarHBondContact O-N 3.29Å; A44-P60 HydrophobicContact CB-CB 4.41Å; A44-P60 HydrophobicContact CB-CG 3.96Å
45	T	91.4	Very high	89.6	Confident	33 Å²	33	67.8 Å²	67.8	20%	0.202	37%	0.367	C	S	.	.	H	α-helix	trans	-61.1	-41.3	177.7	50.9	0	0	0	0	112.9	F41 I42 M47 T48 L49 P60	F41-T45 HydrophobicContact CD1-CG2 4.41Å; F41-T45 HydrophobicContact CD2-CG2 4.18Å; F41-T45 HydrophobicContact CE1-CG2 3.97Å; F41-T45 HydrophobicContact CE2-CG2 3.73Å; F41-T45 HydrophobicContact CZ-CG2 3.62Å; F41-T45 WeakPolarHBondContact O-CG2 3.46Å; F41-T45 PolarHBondContact O-N 3.38Å; F41-T45 PolarHBondContact O-OG1 3.47Å; I42-T45 WeakPolarHBondContact CA-OG1 3.47Å; I42-T45 PolarHBondContact O-OG1 2.91Å; T45-M47 VanDerWaalsContact C-N 3.31Å; T45-M47 PolarHBondContact O-N 3.39Å; T45-T48 PolarHBondContact O-N 3.04Å; T45-T48 PolarHBondContact O-OG1 3.29Å; T45-L49 WeakPolarHBondContact O-CB 3.44Å; T45-L49 WeakPolarHBondContact O-CG 3.24Å; T45-L49 PolarHBondContact O-N 3.19Å; T45-P60 HydrophobicContact CG2-CB 3.63Å; T45-P60 HydrophobicContact CG2-CG 3.86Å
46	L	91.2	Very high	89.2	Confident	43 Å²	43	67.7 Å²	67.7	23%	0.225	36%	0.364	C	S	.	.	H	α-helix	trans	-64	-38	175.5	-75	170.7	0	0	0	112	I4 Y5 I8 I42 M43 A44 N50	I4-L46 HydrophobicContact CG2-CD1 3.61Å; Y5-L46 HydrophobicContact CE1-CB 3.75Å; Y5-L46 HydrophobicContact CE1-CD1 4.3Å; Y5-L46 PolarHBondContact OH-O 3.42Å; I8-L46 HydrophobicContact CD1-CD1 3.3Å; I42-L46 HydrophobicContact CG2-CD1 3.91Å; I42-L46 HydrophobicContact CG2-CG 4.38Å; I42-L46 WeakPolarHBondContact O-CB 3.35Å; I42-L46 VanDerWaalsContact O-CG 3.28Å; I42-L46 WeakPolarHBondContact O-CG 3.45Å; I42-L46 PolarHBondContact O-N 3.3Å; M43-L46 PolarHBondContact O-N 2.98Å; A44-L46 PolarHBondContact O-N 3.15Å; L46-N50 WeakPolarHBondContact O-CB 3.39Å; L46-N50 VanDerWaalsContact O-CG 3.32Å; L46-N50 PolarHBondContact O-N 3.39Å; L46-N50 PolarHBondContact O-ND2 2.96Å
47	M	88.7	Confident	88.7	Confident	90 Å²	90	69.7 Å²	69.7	44%	0.443	38%	0.375	S	S	.	.	H	α-helix	trans	-66.2	-43.3	176.1	-72	-64.9	-176.3	0	0	112.2	Y5 M43 A44 T45 N50 T51	Y5-M47 HydrophobicContact CD1-CE 4.06Å; Y5-M47 HydrophobicContact CD2-CE 4.37Å; Y5-M47 HydrophobicContact CE1-CE 3.57Å; Y5-M47 HydrophobicContact CE1-CG 4.08Å; Y5-M47 HydrophobicContact CE1-SD 3.98Å; Y5-M47 HydrophobicContact CE2-CE 3.98Å; Y5-M47 HydrophobicContact CE2-SD 4.26Å; Y5-M47 HydrophobicContact CG-CE 4.41Å; Y5-M47 VanDerWaalsContact CZ-SD 3.55Å; Y5-M47 PolarHBondContact OH-N 3.19Å; Y5-M47 PolarHBondContact OH-SD 3.12Å; M43-M47 WeakPolarHBondContact O-CG 3.44Å; M43-M47 PolarHBondContact O-N 2.96Å; M43-M47 VanDerWaalsContact O-N 3.08Å; M43-M47 HydrophobicContact SD-CE 4.21Å; A44-M47 WeakPolarHBondContact O-CB 3.21Å; A44-M47 PolarHBondContact O-N 3.12Å; A44-M47 VanDerWaalsContact O-N 3.17Å; T45-M47 VanDerWaalsContact C-N 3.31Å; T45-M47 PolarHBondContact O-N 3.39Å; M47-N50 PolarHBondContact O-N 2.94Å; M47-T51 WeakPolarHBondContact O-CG2 3.48Å; M47-T51 PolarHBondContact O-N 3.3Å; M47-T51 VanDerWaalsContact O-N 3.11Å; M47-T51 PolarHBondContact O-OG1 3.07Å
48	T	89.6	Confident	88.5	Confident	13 Å²	13	73.5 Å²	73.5	8%	0.08	39%	0.394	C	S	.	.	H	α-helix	trans	-67.6	-37.3	178.5	64.9	0	0	0	0	112.1	A44 T45 T51 H52 S53 A56 N57 P60	A44-T48 WeakPolarHBondContact O-CG2 3.36Å; A44-T48 PolarHBondContact O-N 3.29Å; T45-T48 PolarHBondContact O-N 3.04Å; T45-T48 PolarHBondContact O-OG1 3.29Å; T48-T51 PolarHBondContact O-OG1 2.99Å; T48-H52 PolarHBondContact O-N 3.33Å; T48-S53 PolarHBondContact O-N 3.01Å; T48-A56 HydrophobicContact CG2-CB 3.64Å; T48-N57 VanDerWaalsContact CB-OD1 3.26Å; T48-N57 WeakPolarHBondContact CB-OD1 3.43Å; T48-N57 PolarHBondContact OG1-OD1 3.38Å; T48-P60 HydrophobicContact CG2-CG 4.34Å
49	L	87.9	Confident	88.3	Confident	107 Å²	107	72.7 Å²	72.7	56%	0.56	39%	0.393	S	S	*	.	H	α-helix	trans	-66.6	-43.7	175.3	-71.9	169.8	0	0	0	111.9	T45 T51 H52	T45-L49 WeakPolarHBondContact O-CB 3.44Å; T45-L49 WeakPolarHBondContact O-CG 3.24Å; T45-L49 PolarHBondContact O-N 3.19Å; L49-T51 VanDerWaalsContact C-N 3.31Å; L49-T51 PolarHBondContact O-N 3.46Å; L49-H52 PolarHBondContact O-N 3.34Å
50	N	86.9	Confident	88.1	Confident	83 Å²	83	72.4 Å²	72.4	44%	0.444	39%	0.392	S	S	.	.	H	α-helix	trans	-66.5	-31.5	179.2	-81.8	-29	0	0	0	113.2	Y5 L46 M47	Y5-N50 PolarHBondContact OH-ND2 3.42Å; L46-N50 WeakPolarHBondContact O-CB 3.39Å; L46-N50 VanDerWaalsContact O-CG 3.32Å; L46-N50 PolarHBondContact O-N 3.39Å; L46-N50 PolarHBondContact O-ND2 2.96Å; M47-N50 PolarHBondContact O-N 2.94Å
51	T	85.6	Confident	88.1	Confident	94 Å²	94	74.2 Å²	74.2	58%	0.577	40%	0.4	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.8	0.3	179.8	52.9	0	0	0	0	113.3	M47 T48 L49 S53	M47-T51 WeakPolarHBondContact O-CG2 3.48Å; M47-T51 PolarHBondContact O-N 3.3Å; M47-T51 VanDerWaalsContact O-N 3.11Å; M47-T51 PolarHBondContact O-OG1 3.07Å; T48-T51 PolarHBondContact O-OG1 2.99Å; L49-T51 VanDerWaalsContact C-N 3.31Å; L49-T51 PolarHBondContact O-N 3.46Å; T51-S53 PolarHBondContact O-N 2.97Å; T51-S53 PolarHBondContact OG1-OG 3.17Å
52	H	83.9	Confident	88.1	Confident	166 Å²	166	73.3 Å²	73.3	77%	0.769	40%	0.404	S	S	*	.	T	Hydrogen-bonded Turn	trans	50.4	26.8	-176.1	-64.5	-68.2	0	0	0	114.1	T48 L49 L54	T48-H52 PolarHBondContact O-N 3.33Å; L49-H52 PolarHBondContact O-N 3.34Å; H52-L54 PolarHBondContact O-N 3.34Å
53	S	80.1	Confident	88	Confident	42 Å²	42	73.9 Å²	73.9	29%	0.294	41%	0.406	S	S	.	.			trans	-88.8	89.8	-177.3	62.3	0	0	0	0	110.7	T48 T51 L55 A56	T48-S53 PolarHBondContact O-N 3.01Å; T51-S53 PolarHBondContact O-N 2.97Å; T51-S53 PolarHBondContact OG1-OG 3.17Å; S53-L55 VanDerWaalsContact C-N 3.26Å; S53-L55 PolarHBondContact O-N 3.43Å; S53-A56 PolarHBondContact O-N 3.49Å; S53-A56 VanDerWaalsContact OG-CB 3.24Å; S53-A56 WeakPolarHBondContact OG-CB 3.31Å
54	L	79.4	Confident	88.1	Confident	145 Å²	145	76.2 Å²	76.2	76%	0.759	42%	0.418	S	S	*	.	G	3₁₀ helix	trans	-59.1	-34.5	-178.2	-68.3	170.1	0	0	0	113.4	H52 A56 N57	H52-L54 PolarHBondContact O-N 3.34Å; L54-A56 VanDerWaalsContact C-N 3.3Å; L54-A56 PolarHBondContact O-N 2.94Å; L54-N57 WeakPolarHBondContact O-CB 3.47Å; L54-N57 PolarHBondContact O-N 3.07Å
55	L	82.6	Confident	88.3	Confident	159 Å²	159	78.9 Å²	78.9	83%	0.832	43%	0.432	S	S	*	.	G	3₁₀ helix	trans	-65.1	-32	176.7	-79.9	153.3	0	0	0	112.7	S53 N57	S53-L55 VanDerWaalsContact C-N 3.26Å; S53-L55 PolarHBondContact O-N 3.43Å; L55-N57 PolarHBondContact O-N 2.9Å
56	A	84.9	Confident	88.4	Confident	30 Å²	30	84.2 Å²	84.2	25%	0.248	45%	0.452	C	S	.	.	G	3₁₀ helix	trans	-74.5	-13.3	-179.1	0	0	0	0	0	112.9	T48 S53 L54 I58 V59 P60	T48-A56 HydrophobicContact CG2-CB 3.64Å; S53-A56 PolarHBondContact O-N 3.49Å; S53-A56 VanDerWaalsContact OG-CB 3.24Å; S53-A56 WeakPolarHBondContact OG-CB 3.31Å; L54-A56 VanDerWaalsContact C-N 3.3Å; L54-A56 PolarHBondContact O-N 2.94Å; A56-I58 PolarHBondContact O-N 3.44Å; A56-I58 VanDerWaalsContact O-N 3.13Å; A56-V59 WeakPolarHBondContact O-CB 3.46Å; A56-V59 PolarHBondContact O-N 3.39Å; A56-P60 WeakPolarHBondContact O-CD 3.43Å
57	N	83.4	Confident	88.5	Confident	58 Å²	58	82.9 Å²	82.9	31%	0.31	45%	0.448	S	S	.	.	G	3₁₀ helix	trans	-64.1	-16.2	177.3	-75.8	-10.2	0	0	0	113.5	T48 L54 L55 V59 P60	T48-N57 VanDerWaalsContact CB-OD1 3.26Å; T48-N57 WeakPolarHBondContact CB-OD1 3.43Å; T48-N57 PolarHBondContact OG1-OD1 3.38Å; L54-N57 WeakPolarHBondContact O-CB 3.47Å; L54-N57 PolarHBondContact O-N 3.07Å; L55-N57 PolarHBondContact O-N 2.9Å; N57-V59 VanDerWaalsContact C-N 3.27Å; N57-P60 WeakPolarHBondContact O-CD 3.27Å
58	I	89.9	Confident	88.6	Confident	116 Å²	116	81.6 Å²	81.6	60%	0.595	45%	0.451	S	S	*	.	H	α-helix	trans	-67.5	-31.3	172.1	-60.6	173.1	0	0	0	110.6	A56 I61 A62	A56-I58 PolarHBondContact O-N 3.44Å; A56-I58 VanDerWaalsContact O-N 3.13Å; I58-I61 PolarHBondContact O-N 3.42Å; I58-A62 WeakPolarHBondContact O-CB 3.43Å; I58-A62 PolarHBondContact O-N 2.92Å
59	V	89.6	Confident	88.8	Confident	87 Å²	87	84.3 Å²	84.3	53%	0.527	47%	0.47	S	S	.	.	H	α-helix	trans	-64.7	-50.9	-174.6	178	0	0	0	0	112.4	A56 N57 I61 A62 M63	A56-V59 WeakPolarHBondContact O-CB 3.46Å; A56-V59 PolarHBondContact O-N 3.39Å; N57-V59 VanDerWaalsContact C-N 3.27Å; V59-I61 VanDerWaalsContact C-N 3.26Å; V59-I61 PolarHBondContact O-N 3.27Å; V59-A62 PolarHBondContact O-N 3.13Å; V59-M63 HydrophobicContact CG1-CG 4.44Å; V59-M63 WeakPolarHBondContact O-CB 3.36Å; V59-M63 VanDerWaalsContact O-CG 3.29Å; V59-M63 WeakPolarHBondContact O-CG 3.49Å; V59-M63 PolarHBondContact O-N 3.46Å
60	P	90.9	Very high	89	Confident	3 Å²	3	84.7 Å²	84.7	2%	0.019	47%	0.469	C	S	.	.	H	α-helix	trans	-58.6	-34.7	175.2	-23.6	31.6	0	0	0	113.9	F41 A44 T45 T48 A56 N57 L64	F41-P60 HydrophobicContact CD2-CB 3.64Å; F41-P60 WeakPolarHBondContact CD2-O 3.17Å; F41-P60 HydrophobicContact CE2-CB 3.48Å; F41-P60 VanDerWaalsContact CE2-CB 3.48Å; A44-P60 HydrophobicContact CB-CB 4.41Å; A44-P60 HydrophobicContact CB-CG 3.96Å; T45-P60 HydrophobicContact CG2-CB 3.63Å; T45-P60 HydrophobicContact CG2-CG 3.86Å; T48-P60 HydrophobicContact CG2-CG 4.34Å; A56-P60 WeakPolarHBondContact O-CD 3.43Å; N57-P60 WeakPolarHBondContact O-CD 3.27Å; P60-L64 PolarHBondContact O-N 2.94Å; P60-L64 VanDerWaalsContact O-N 3.12Å
61	I	92.4	Very high	89.2	Confident	107 Å²	107	81.8 Å²	81.8	55%	0.549	46%	0.457	S	S	.	.	H	α-helix	trans	-70.8	-47	179	-59.6	170.1	0	0	0	110.1	I58 V59 M63 L64 V65	I58-I61 PolarHBondContact O-N 3.42Å; V59-I61 VanDerWaalsContact C-N 3.26Å; V59-I61 PolarHBondContact O-N 3.27Å; I61-M63 VanDerWaalsContact C-N 3.29Å; I61-M63 PolarHBondContact O-N 2.92Å; I61-L64 PolarHBondContact O-N 3.27Å; I61-L64 VanDerWaalsContact O-N 3.15Å; I61-V65 WeakPolarHBondContact O-CG2 3.34Å; I61-V65 PolarHBondContact O-N 3.32Å; I61-V65 VanDerWaalsContact O-N 3.12Å
62	A	93.9	Very high	89.5	Confident	40 Å²	40	80 Å²	80	33%	0.331	45%	0.452	S	S	.	.	H	α-helix	trans	-58.7	-42.6	175.7	0	0	0	0	0	111.4	I58 V59 L64 V65 F66	I58-A62 WeakPolarHBondContact O-CB 3.43Å; I58-A62 PolarHBondContact O-N 2.92Å; V59-A62 PolarHBondContact O-N 3.13Å; A62-L64 VanDerWaalsContact C-N 3.34Å; A62-L64 PolarHBondContact O-N 3.03Å; A62-V65 PolarHBondContact O-N 3.44Å; A62-F66 WeakPolarHBondContact O-CD2 3.5Å; A62-F66 PolarHBondContact O-N 3.35Å
63	M	93	Very high	89.9	Confident	79 Å²	79	76.5 Å²	76.5	39%	0.389	44%	0.442	S	S	.	.	H	α-helix	trans	-56.9	-43.4	174.3	-75.5	-72.2	-66.7	0	0	112.6	M37 V59 I61 F66 A67	M37-M63 HydrophobicContact CE-CE 4.44Å; V59-M63 HydrophobicContact CG1-CG 4.44Å; V59-M63 WeakPolarHBondContact O-CB 3.36Å; V59-M63 VanDerWaalsContact O-CG 3.29Å; V59-M63 WeakPolarHBondContact O-CG 3.49Å; V59-M63 PolarHBondContact O-N 3.46Å; I61-M63 VanDerWaalsContact C-N 3.29Å; I61-M63 PolarHBondContact O-N 2.92Å; M63-F66 PolarHBondContact O-N 3.37Å; M63-A67 WeakPolarHBondContact O-CB 3.39Å; M63-A67 PolarHBondContact O-N 3.07Å
64	L	93.3	Very high	90.5	Very high	77 Å²	77	75.2 Å²	75.2	40%	0.403	44%	0.435	S	S	.	.	H	α-helix	trans	-65.1	-37.8	177.3	-83.1	175.1	0	0	0	113.1	F41 P60 I61 A62 A67 A68	F41-L64 HydrophobicContact CB-CD2 4.4Å; F41-L64 HydrophobicContact CD1-CD1 4.41Å; F41-L64 HydrophobicContact CD2-CD1 3.49Å; F41-L64 VanDerWaalsContact CD2-CD1 3.49Å; F41-L64 HydrophobicContact CD2-CD2 4.18Å; F41-L64 HydrophobicContact CD2-CG 3.52Å; F41-L64 HydrophobicContact CE1-CD1 4.21Å; F41-L64 HydrophobicContact CE2-CD1 3.24Å; F41-L64 HydrophobicContact CE2-CG 3.81Å; F41-L64 HydrophobicContact CG-CD1 4.07Å; F41-L64 HydrophobicContact CG-CD2 4.21Å; F41-L64 HydrophobicContact CG-CG 4.05Å; F41-L64 HydrophobicContact CZ-CD1 3.64Å; P60-L64 PolarHBondContact O-N 2.94Å; P60-L64 VanDerWaalsContact O-N 3.12Å; I61-L64 PolarHBondContact O-N 3.27Å; I61-L64 VanDerWaalsContact O-N 3.15Å; A62-L64 VanDerWaalsContact C-N 3.34Å; A62-L64 PolarHBondContact O-N 3.03Å; L64-A67 WeakPolarHBondContact O-CB 3.38Å; L64-A67 PolarHBondContact O-N 2.73Å; L64-A68 PolarHBondContact O-N 3.49Å
65	V	95.7	Very high	91	Very high	85 Å²	85	72.1 Å²	72.1	52%	0.515	42%	0.419	S	S	.	.	H	α-helix	trans	-63.4	-47.3	178.5	177.1	0	0	0	0	110.2	I61 A62 A67 A68 C69	I61-V65 WeakPolarHBondContact O-CG2 3.34Å; I61-V65 PolarHBondContact O-N 3.32Å; I61-V65 VanDerWaalsContact O-N 3.12Å; A62-V65 PolarHBondContact O-N 3.44Å; V65-A67 VanDerWaalsContact C-N 3.34Å; V65-A67 PolarHBondContact O-N 3.21Å; V65-A68 PolarHBondContact O-N 2.95Å; V65-C69 PolarHBondContact O-N 2.9Å; V65-C69 VanDerWaalsContact O-N 3.09Å; V65-C69 PolarHBondContact O-SG 3.27Å
66	F	93	Very high	91.4	Very high	144 Å²	144	67.5 Å²	67.5	63%	0.632	40%	0.403	S	S	*	.	H	α-helix	trans	-63.8	-39	176.2	-73.2	-66.9	0	0	0	112.3	A62 M63 A68 C69 E70	A62-F66 WeakPolarHBondContact O-CD2 3.5Å; A62-F66 PolarHBondContact O-N 3.35Å; M63-F66 PolarHBondContact O-N 3.37Å; F66-A68 VanDerWaalsContact C-N 3.33Å; F66-A68 PolarHBondContact O-N 3.47Å; F66-C69 WeakPolarHBondContact O-CB 3.49Å; F66-C69 PolarHBondContact O-N 3.4Å; F66-E70 PolarHBondContact O-N 2.91Å
67	A	92.9	Very high	91.6	Very high	15 Å²	15	70.9 Å²	70.9	12%	0.124	42%	0.417	C	S	.	.	H	α-helix	trans	-56.9	-45.7	174.6	0	0	0	0	0	112.4	M37 M63 L64 V65 C69 E70 A71	M37-A67 HydrophobicContact CB-CB 3.99Å; M37-A67 HydrophobicContact CE-CB 3.35Å; M37-A67 HydrophobicContact CG-CB 3.95Å; M37-A67 HydrophobicContact SD-CB 4.5Å; M63-A67 WeakPolarHBondContact O-CB 3.39Å; M63-A67 PolarHBondContact O-N 3.07Å; L64-A67 WeakPolarHBondContact O-CB 3.38Å; L64-A67 PolarHBondContact O-N 2.73Å; V65-A67 VanDerWaalsContact C-N 3.34Å; V65-A67 PolarHBondContact O-N 3.21Å; A67-C69 VanDerWaalsContact C-N 3.33Å; A67-C69 PolarHBondContact O-N 3.07Å; A67-E70 PolarHBondContact O-N 3.05Å; A67-A71 WeakPolarHBondContact O-CB 3.33Å; A67-A71 PolarHBondContact O-N 3.39Å
68	A	92.2	Very high	91.8	Very high	63 Å²	63	68.7 Å²	68.7	52%	0.521	41%	0.405	S	S	.	.	H	α-helix	trans	-66.3	-36.5	178.8	0	0	0	0	0	111.9	L64 V65 F66 A71 A72	L64-A68 PolarHBondContact O-N 3.49Å; V65-A68 PolarHBondContact O-N 2.95Å; F66-A68 VanDerWaalsContact C-N 3.33Å; F66-A68 PolarHBondContact O-N 3.47Å; A68-A71 PolarHBondContact O-N 2.95Å; A68-A72 WeakPolarHBondContact O-CB 3.48Å; A68-A72 PolarHBondContact O-N 3.48Å
69	C	93.4	Very high	91.8	Very high	71 Å²	71	67 Å²	67	48%	0.48	40%	0.4	S	S	.	.	H	α-helix	trans	-64.1	-44.6	174.2	-66.5	0	0	0	0	112	V65 F66 A67 A72 V73	V65-C69 PolarHBondContact O-N 2.9Å; V65-C69 VanDerWaalsContact O-N 3.09Å; V65-C69 PolarHBondContact O-SG 3.27Å; F66-C69 WeakPolarHBondContact O-CB 3.49Å; F66-C69 PolarHBondContact O-N 3.4Å; A67-C69 VanDerWaalsContact C-N 3.33Å; A67-C69 PolarHBondContact O-N 3.07Å; C69-A72 PolarHBondContact O-N 2.86Å; C69-V73 WeakPolarHBondContact O-CG2 3.41Å; C69-V73 PolarHBondContact O-N 3.04Å; C69-V73 VanDerWaalsContact O-N 3.07Å
70	E	91.1	Very high	91.6	Very high	114 Å²	114	65.5 Å²	65.5	53%	0.533	39%	0.393	S	S	.	.	H	α-helix	trans	-61.8	-43.8	175.8	-71.9	-178.9	174.7	0	0	111.7	F66 A67 A72 V73 G74	F66-E70 PolarHBondContact O-N 2.91Å; A67-E70 PolarHBondContact O-N 3.05Å; E70-A72 PolarHBondContact O-N 3.31Å; E70-V73 PolarHBondContact O-N 3.16Å; E70-G74 PolarHBondContact O-N 3.11Å
71	A	91.4	Very high	91.4	Very high	22 Å²	22	66.6 Å²	66.6	18%	0.182	40%	0.399	C	S	.	.	H	α-helix	trans	-62.7	-41.6	176.5	0	0	0	0	0	112.2	A67 A68 V73 G74 L75	A67-A71 WeakPolarHBondContact O-CB 3.33Å; A67-A71 PolarHBondContact O-N 3.39Å; A68-A71 PolarHBondContact O-N 2.95Å; A71-V73 PolarHBondContact O-N 3.38Å; A71-G74 PolarHBondContact O-N 3.44Å; A71-L75 WeakPolarHBondContact O-CG 3.18Å; A71-L75 PolarHBondContact O-N 3.36Å
72	A	92.6	Very high	91.1	Very high	58 Å²	58	63 Å²	63	48%	0.479	38%	0.383	S	S	.	.	H	α-helix	trans	-62.1	-43.3	176.9	0	0	0	0	0	112.1	A68 C69 E70 L75 A76	A68-A72 WeakPolarHBondContact O-CB 3.48Å; A68-A72 PolarHBondContact O-N 3.48Å; C69-A72 PolarHBondContact O-N 2.86Å; E70-A72 PolarHBondContact O-N 3.31Å; A72-L75 PolarHBondContact O-N 2.78Å; A72-A76 WeakPolarHBondContact O-CB 3.49Å; A72-A76 PolarHBondContact O-N 3.08Å
73	V	92.9	Very high	90.8	Very high	92 Å²	92	67.2 Å²	67.2	56%	0.558	40%	0.4	S	S	*	.	H	α-helix	trans	-66.3	-41.4	174.9	176.1	0	0	0	0	111	C69 E70 A71 L75 A76 L77	C69-V73 WeakPolarHBondContact O-CG2 3.41Å; C69-V73 PolarHBondContact O-N 3.04Å; C69-V73 VanDerWaalsContact O-N 3.07Å; E70-V73 PolarHBondContact O-N 3.16Å; A71-V73 PolarHBondContact O-N 3.38Å; V73-L75 VanDerWaalsContact C-N 3.35Å; V73-L75 PolarHBondContact O-N 2.96Å; V73-A76 PolarHBondContact O-N 3.44Å; V73-L77 HydrophobicContact CG1-CD1 4.46Å; V73-L77 WeakPolarHBondContact O-CG 3.26Å; V73-L77 PolarHBondContact O-N 3.43Å
74	G	91.3	Very high	90.4	Very high	14 Å²	14	68.2 Å²	68.2	14%	0.144	41%	0.411	C	S	.	.	H	α-helix	trans	-59	-43	176	0	0	0	0	0	113	E70 A71 L77 L78	E70-G74 PolarHBondContact O-N 3.11Å; A71-G74 PolarHBondContact O-N 3.44Å; G74-L77 PolarHBondContact O-N 2.94Å; G74-L78 PolarHBondContact O-N 2.95Å
75	L	89.8	Confident	89.8	Confident	80 Å²	80	68.3 Å²	68.3	42%	0.419	41%	0.406	S	S	.	.	H	α-helix	trans	-67.7	-39.8	174.9	-72.3	170.1	0	0	0	112.3	M27 L30 A71 A72 V73 L77 L78 V79	M27-L75 HydrophobicContact CE-CD2 4.47Å; M27-L75 HydrophobicContact SD-CD2 4.27Å; L30-L75 HydrophobicContact CD1-CD2 4.05Å; L30-L75 HydrophobicContact CD1-CG 4.5Å; A71-L75 WeakPolarHBondContact O-CG 3.18Å; A71-L75 PolarHBondContact O-N 3.36Å; A72-L75 PolarHBondContact O-N 2.78Å; V73-L75 VanDerWaalsContact C-N 3.35Å; V73-L75 PolarHBondContact O-N 2.96Å; L75-L77 VanDerWaalsContact C-N 3.3Å; L75-L77 PolarHBondContact O-N 3.24Å; L75-L78 WeakPolarHBondContact O-CB 3.31Å; L75-L78 PolarHBondContact O-N 3.32Å; L75-L78 VanDerWaalsContact O-N 3.16Å; L75-V79 WeakPolarHBondContact O-CG2 3.46Å; L75-V79 PolarHBondContact O-N 3.41Å
76	A	92.2	Very high	89	Confident	62 Å²	62	67.1 Å²	67.1	51%	0.512	41%	0.411	S	S	.	.	H	α-helix	trans	-60.7	-40.6	175.6	0	0	0	0	0	111.8	A72 V73 V79 S80	A72-A76 WeakPolarHBondContact O-CB 3.49Å; A72-A76 PolarHBondContact O-N 3.08Å; V73-A76 PolarHBondContact O-N 3.44Å; A76-V79 PolarHBondContact O-N 3.45Å; A76-S80 PolarHBondContact O-N 2.93Å; A76-S80 VanDerWaalsContact O-N 3.1Å
77	L	87.8	Confident	88.1	Confident	101 Å²	101	64.9 Å²	64.9	53%	0.529	41%	0.405	S	S	.	.	H	α-helix	trans	-64.1	-42.3	173.1	-73.3	172.5	0	0	0	111.7	V73 G74 L75 V79 S80 I81	V73-L77 HydrophobicContact CG1-CD1 4.46Å; V73-L77 WeakPolarHBondContact O-CG 3.26Å; V73-L77 PolarHBondContact O-N 3.43Å; G74-L77 PolarHBondContact O-N 2.94Å; L75-L77 VanDerWaalsContact C-N 3.3Å; L75-L77 PolarHBondContact O-N 3.24Å; L77-V79 VanDerWaalsContact C-N 3.32Å; L77-V79 PolarHBondContact O-N 2.93Å; L77-S80 WeakPolarHBondContact O-CB 3.37Å; L77-S80 PolarHBondContact O-N 2.8Å; L77-S80 PolarHBondContact O-OG 3.44Å; L77-I81 WeakPolarHBondContact O-CG1 3.28Å; L77-I81 PolarHBondContact O-N 3.02Å
78	L	88.1	Confident	87.2	Confident	13 Å²	13	66.5 Å²	66.5	7%	0.068	41%	0.412	C	S	.	.	H	α-helix	trans	-59.9	-43.2	177.4	-167	157.2	0	0	0	111.8	L26 M27 L30 G74 L75 S80 I81 S82 D88	L26-L78 HydrophobicContact CB-CD1 4.12Å; L26-L78 HydrophobicContact CD2-CB 3.92Å; L26-L78 HydrophobicContact CD2-CD1 3.8Å; L26-L78 HydrophobicContact CD2-CG 3.93Å; L26-L78 HydrophobicContact CG-CD1 4.49Å; M27-L78 HydrophobicContact CB-CD1 4.48Å; M27-L78 HydrophobicContact CG-CD1 3.65Å; M27-L78 HydrophobicContact SD-CD1 3.18Å; M27-L78 WeakPolarHBondContact SD-CD1 3.22Å; M27-L78 HydrophobicContact SD-CD2 4.23Å; M27-L78 HydrophobicContact SD-CG 4.35Å; L30-L78 HydrophobicContact CD1-CD1 3.77Å; G74-L78 PolarHBondContact O-N 2.95Å; L75-L78 WeakPolarHBondContact O-CB 3.31Å; L75-L78 PolarHBondContact O-N 3.32Å; L75-L78 VanDerWaalsContact O-N 3.16Å; L78-S80 VanDerWaalsContact C-N 3.29Å; L78-S80 PolarHBondContact O-N 2.98Å; L78-I81 PolarHBondContact O-N 2.96Å; L78-S82 PolarHBondContact O-N 2.91Å; L78-S82 PolarHBondContact O-OG 3.4Å; L78-D88 WeakPolarHBondContact CD2-OD1 3.36Å
79	V	89.4	Confident	86.4	Confident	79 Å²	79	67.8 Å²	67.8	48%	0.479	40%	0.404	S	S	.	.	H	α-helix	trans	-60.9	-37.8	173.8	174.7	0	0	0	0	111.7	L75 A76 L77 S82 N83	L75-V79 WeakPolarHBondContact O-CG2 3.46Å; L75-V79 PolarHBondContact O-N 3.41Å; A76-V79 PolarHBondContact O-N 3.45Å; L77-V79 VanDerWaalsContact C-N 3.32Å; L77-V79 PolarHBondContact O-N 2.93Å; V79-S82 WeakPolarHBondContact CA-OG 3.25Å; V79-S82 PolarHBondContact O-OG 3.23Å; V79-N83 WeakPolarHBondContact O-CB 3.34Å; V79-N83 PolarHBondContact O-N 3.2Å; V79-N83 PolarHBondContact O-ND2 3.5Å; V79-N83 VanDerWaalsContact O-ND2 3.16Å
80	S	87	Confident	85.4	Confident	56 Å²	56	66.6 Å²	66.6	39%	0.392	40%	0.395	S	S	.	.	H	α-helix	trans	-65.9	-40.2	175.8	75.5	0	0	0	0	112.4	A76 L77 L78 N83 T84	A76-S80 PolarHBondContact O-N 2.93Å; A76-S80 VanDerWaalsContact O-N 3.1Å; L77-S80 WeakPolarHBondContact O-CB 3.37Å; L77-S80 PolarHBondContact O-N 2.8Å; L77-S80 PolarHBondContact O-OG 3.44Å; L78-S80 VanDerWaalsContact C-N 3.29Å; L78-S80 PolarHBondContact O-N 2.98Å; S80-N83 PolarHBondContact O-N 3.04Å; S80-T84 WeakPolarHBondContact O-CG2 3.48Å; S80-T84 PolarHBondContact O-N 3.44Å; S80-T84 VanDerWaalsContact O-N 3.13Å; S80-T84 PolarHBondContact O-OG1 3.17Å
81	I	86	Confident	84.3	Confident	26 Å²	26	68.2 Å²	68.2	13%	0.133	40%	0.402	C	S	.	.	H	α-helix	trans	-65.7	-46.5	177.8	-65.4	163.2	0	0	0	110	L26 L77 L78 N83 T84 Y85 L93	L26-I81 HydrophobicContact CD2-CD1 4.32Å; L77-I81 WeakPolarHBondContact O-CG1 3.28Å; L77-I81 PolarHBondContact O-N 3.02Å; L78-I81 PolarHBondContact O-N 2.96Å; I81-N83 VanDerWaalsContact C-N 3.31Å; I81-N83 PolarHBondContact O-N 2.99Å; I81-T84 WeakPolarHBondContact CA-OG1 3.49Å; I81-T84 PolarHBondContact O-N 2.94Å; I81-T84 VanDerWaalsContact O-N 3.1Å; I81-T84 PolarHBondContact O-OG1 3.21Å; I81-Y85 HydrophobicContact CG2-CD2 4.09Å; I81-Y85 PolarHBondContact O-N 3.42Å; I81-L93 HydrophobicContact CD1-CD1 4.18Å; I81-L93 HydrophobicContact CG1-CD2 4.38Å; I81-L93 HydrophobicContact CG2-CD2 4.46Å
82	S	86.1	Confident	83.3	Confident	32 Å²	32	69.7 Å²	69.7	22%	0.224	41%	0.406	C	S	.	.	H	α-helix	trans	-64	-35.9	178.9	72.5	0	0	0	0	112.2	L78 V79 T84 G86 D88	L78-S82 PolarHBondContact O-N 2.91Å; L78-S82 PolarHBondContact O-OG 3.4Å; V79-S82 WeakPolarHBondContact CA-OG 3.25Å; V79-S82 PolarHBondContact O-OG 3.23Å; S82-T84 VanDerWaalsContact C-N 3.34Å; S82-T84 PolarHBondContact O-N 3.3Å; S82-G86 WeakPolarHBondContact O-CA 3.33Å; S82-G86 PolarHBondContact O-N 3.25Å; S82-D88 VanDerWaalsContact CB-OD1 3.3Å; S82-D88 WeakPolarHBondContact CB-OD1 3.4Å
83	N	88.4	Confident	82.5	Confident	129 Å²	129	70.2 Å²	70.2	69%	0.69	40%	0.401	S	S	*	.	H	α-helix	trans	-66.1	-33.2	172.8	-74.3	-26.8	0	0	0	113.1	V79 S80 I81	V79-N83 WeakPolarHBondContact O-CB 3.34Å; V79-N83 PolarHBondContact O-N 3.2Å; V79-N83 PolarHBondContact O-ND2 3.5Å; V79-N83 VanDerWaalsContact O-ND2 3.16Å; S80-N83 PolarHBondContact O-N 3.04Å; I81-N83 VanDerWaalsContact C-N 3.31Å; I81-N83 PolarHBondContact O-N 2.99Å
84	T	84.2	Confident	81.9	Confident	100 Å²	100	69.8 Å²	69.8	61%	0.613	40%	0.395	S	S	*	.	H	α-helix	trans	-83.1	-38.7	179.8	51.3	0	0	0	0	114.4	S80 I81 S82	S80-T84 WeakPolarHBondContact O-CG2 3.48Å; S80-T84 PolarHBondContact O-N 3.44Å; S80-T84 VanDerWaalsContact O-N 3.13Å; S80-T84 PolarHBondContact O-OG1 3.17Å; I81-T84 WeakPolarHBondContact CA-OG1 3.49Å; I81-T84 PolarHBondContact O-N 2.94Å; I81-T84 VanDerWaalsContact O-N 3.1Å; I81-T84 PolarHBondContact O-OG1 3.21Å; S82-T84 VanDerWaalsContact C-N 3.34Å; S82-T84 PolarHBondContact O-N 3.3Å
85	Y	80.8	Confident	81.3	Confident	79 Å²	79	75.2 Å²	75.2	31%	0.31	42%	0.42	S	S	.	.	H	α-helix	trans	-113.7	-4.5	-172.7	-64.5	-78.1	0	0	0	113.8	I81 L87 N92 L93 L95	I81-Y85 HydrophobicContact CG2-CD2 4.09Å; I81-Y85 PolarHBondContact O-N 3.42Å; Y85-L87 PolarHBondContact O-N 2.8Å; Y85-N92 HydrophobicContact CD1-CB 3.8Å; Y85-N92 HydrophobicContact CD2-CB 4.43Å; Y85-N92 HydrophobicContact CE1-CB 4.23Å; Y85-N92 WeakPolarHBondContact CE1-O 3.26Å; Y85-N92 HydrophobicContact CG-CB 3.9Å; Y85-L93 HydrophobicContact CD2-CD2 4.44Å; Y85-L93 HydrophobicContact CE2-CD2 3.75Å; Y85-L95 WeakPolarHBondContact OH-CD1 3.49Å
86	G	77.7	Confident	81	Confident	60 Å²	60	79.4 Å²	79.4	62%	0.619	44%	0.442	S	S	*	.	S	Bend	trans	70.5	-9	-177.5	0	0	0	0	0	115.2	S82	S82-G86 WeakPolarHBondContact O-CA 3.33Å; S82-G86 PolarHBondContact O-N 3.25Å
87	L	75.3	Confident	80.3	Confident	96 Å²	96	84.4 Å²	84.4	50%	0.503	46%	0.455	S	S	.	.	S	Bend	trans	-144.1	144.1	-173.1	-64.1	169.1	0	0	0	110.9	Y85 Y89	Y85-L87 PolarHBondContact O-N 2.8Å; L87-Y89 HydrophobicContact CB-CD2 3.68Å; L87-Y89 HydrophobicContact CB-CE2 4.16Å; L87-Y89 HydrophobicContact CD1-CD2 3.89Å; L87-Y89 HydrophobicContact CD1-CE2 3.9Å; L87-Y89 HydrophobicContact CD2-CE2 4.38Å; L87-Y89 HydrophobicContact CG-CD2 4.3Å; L87-Y89 HydrophobicContact CG-CE2 4.38Å; L87-Y89 PolarHBondContact O-N 3.14Å
88	D	72.8	Confident	79.6	Confident	49 Å²	49	88 Å²	88	26%	0.262	49%	0.487	S	S	.	.			trans	-80.6	27.3	-177	-55.9	-22.6	0	0	0	113.9	L26 L78 S82	L26-D88 PolarHBondContact N-O 3.3Å; L78-D88 WeakPolarHBondContact CD2-OD1 3.36Å; S82-D88 VanDerWaalsContact CB-OD1 3.3Å; S82-D88 WeakPolarHBondContact CB-OD1 3.4Å
89	Y	76.3	Confident	79.1	Confident	90 Å²	90	91.7 Å²	91.7	35%	0.353	51%	0.507	S	S	.	.	B	Isolated β-bridge	trans	-85.3	124.3	-174.8	-70.1	-52.9	0	0	0	112.1	S24 H25 L87 H91 N92	S24-Y89 WeakPolarHBondContact O-CA 3Å; H25-Y89 AromaticContact CE1-CE1 3.21Å; H25-Y89 WeakPolarHBondContact CE1-CE1 3.41Å; H25-Y89 AromaticContact CE1-CZ 3.73Å; H25-Y89 AromaticContact ND1-CE1 3.71Å; H25-Y89 AromaticContact NE2-CE1 3.65Å; L87-Y89 HydrophobicContact CB-CD2 3.68Å; L87-Y89 HydrophobicContact CB-CE2 4.16Å; L87-Y89 HydrophobicContact CD1-CD2 3.89Å; L87-Y89 HydrophobicContact CD1-CE2 3.9Å; L87-Y89 HydrophobicContact CD2-CE2 4.38Å; L87-Y89 HydrophobicContact CG-CD2 4.3Å; L87-Y89 HydrophobicContact CG-CE2 4.38Å; L87-Y89 PolarHBondContact O-N 3.14Å; Y89-H91 PolarHBondContact O-N 3.35Å; Y89-N92 PolarHBondContact O-N 3.04Å
90	V	71.8	Confident	78.6	Confident	47 Å²	47	92.4 Å²	92.4	29%	0.285	51%	0.509	S	S	.	.	G	3₁₀ helix	trans	-62.7	-31.5	179	-175.7	0	0	0	0	112.1	S24 L26 N92 L93	S24-V90 PolarHBondContact O-N 3.38Å; S24-V90 VanDerWaalsContact O-N 3.11Å; L26-V90 HydrophobicContact CB-CG2 4.3Å; L26-V90 HydrophobicContact CD1-CG2 3.87Å; V90-N92 PolarHBondContact O-N 3.46Å; V90-N92 VanDerWaalsContact O-N 3.13Å; V90-L93 PolarHBondContact O-N 3.34Å
91	H	68.9	Low	78.1	Confident	147 Å²	147	94.4 Å²	94.4	68%	0.681	52%	0.516	S	S	*	.	G	3₁₀ helix	trans	-63.2	-18.8	179.6	-169.3	-65.7	0	0	0	113.5	Y89 L93 N94	Y89-H91 PolarHBondContact O-N 3.35Å; H91-L93 PolarHBondContact O-N 3.45Å; H91-N94 PolarHBondContact O-ND2 3.02Å; H91-N94 PolarHBondContact O-OD1 3.23Å
92	N	70.9	Confident	77.7	Confident	53 Å²	53	98.4 Å²	98.4	28%	0.283	54%	0.538	S	S	.	.	G	3₁₀ helix	trans	-75	-13.7	179.5	-68.1	-5.9	0	0	0	112.6	Y85 Y89 V90 N94	Y85-N92 HydrophobicContact CD1-CB 3.8Å; Y85-N92 HydrophobicContact CD2-CB 4.43Å; Y85-N92 HydrophobicContact CE1-CB 4.23Å; Y85-N92 WeakPolarHBondContact CE1-O 3.26Å; Y85-N92 HydrophobicContact CG-CB 3.9Å; Y89-N92 PolarHBondContact O-N 3.04Å; V90-N92 PolarHBondContact O-N 3.46Å; V90-N92 VanDerWaalsContact O-N 3.13Å; N92-N94 VanDerWaalsContact C-N 3.28Å; N92-N94 PolarHBondContact O-N 2.99Å
93	L	74.8	Confident	77.2	Confident	70 Å²	70	102.6 Å²	102.6	37%	0.366	56%	0.558	S	S	.	*			trans	-86.5	33.2	-176	-62.3	169.5	0	0	0	114.1	I81 Y85 V90 H91	I81-L93 HydrophobicContact CD1-CD1 4.18Å; I81-L93 HydrophobicContact CG1-CD2 4.38Å; I81-L93 HydrophobicContact CG2-CD2 4.46Å; Y85-L93 HydrophobicContact CD2-CD2 4.44Å; Y85-L93 HydrophobicContact CE2-CD2 3.75Å; V90-L93 PolarHBondContact O-N 3.34Å; H91-L93 PolarHBondContact O-N 3.45Å
94	N	80.8	Confident	76.4	Confident	82 Å²	82	100.8 Å²	100.8	44%	0.439	55%	0.549	S	S	.	.	G	3₁₀ helix	trans	-89.1	2.2	-175	-70.2	-3.1	0	0	0	114.8	H91 N92 L96 Q97	H91-N94 PolarHBondContact O-ND2 3.02Å; H91-N94 PolarHBondContact O-OD1 3.23Å; N92-N94 VanDerWaalsContact C-N 3.28Å; N92-N94 PolarHBondContact O-N 2.99Å; N94-L96 PolarHBondContact O-N 3.13Å; N94-Q97 WeakPolarHBondContact O-CB 3.4Å; N94-Q97 PolarHBondContact O-N 3.42Å
95	L	79.3	Confident	75.8	Confident	128 Å²	128	100.9 Å²	100.9	67%	0.67	54%	0.544	S	S	*	.	G	3₁₀ helix	trans	-63.9	-23.7	-177.3	-68.4	173.2	0	0	0	113.9	Y85 Q97	Y85-L95 WeakPolarHBondContact OH-CD1 3.49Å; L95-Q97 VanDerWaalsContact C-N 3.25Å; L95-Q97 PolarHBondContact O-N 3.26Å
96	L	83.1	Confident	75.5	Confident	168 Å²	168	102.5 Å²	102.5	88%	0.88	56%	0.562	S	S	*	*	G	3₁₀ helix	trans	-81.5	1.2	-179.7	-69.9	165	0	0	0	113.7	N94 C98	N94-L96 PolarHBondContact O-N 3.13Å; L96-C98 VanDerWaalsContact C-N 3.29Å
97	Q	76.2	Confident	75.3	Confident	167 Å²	167	106.1 Å²	106.1	78%	0.78	56%	0.558	S	S	*	*	G	3₁₀ helix	trans	-80	-13.1	175.1	-168.5	175.5	-4.8	0	0	112.7	N94 L95	N94-Q97 WeakPolarHBondContact O-CB 3.4Å; N94-Q97 PolarHBondContact O-N 3.42Å; L95-Q97 VanDerWaalsContact C-N 3.25Å; L95-Q97 PolarHBondContact O-N 3.26Å
98	C	73.2	Confident	75.3	Confident	176 Å²	176	107 Å²	107	100%	1.189	56%	0.563	S	S	*	*			trans	-79.7	0	173.8	-62.5	0	0	0	0	111.6	L96	L96-C98 VanDerWaalsContact C-N 3.29Å

Retrieved 98 of 98 residues in 128.2 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).