A0A060X4W0_ONCMY Loading...

Cysteine-rich hydrophobic domain 1

AlphaFold DB (A0A673Z2H0), UniProt , Accession A0A060X4W0, Species ONCMY (Oncorhynchus mykiss, Rainbow trout), Gene chic1, Length 173 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	36.2	Very low	45.7	Very low	241 Å²	241	155.5 Å²	155.5	100%	1.187	86%	0.856	S	S	*	*				0	103	0	-89.2	166.5	170.1	0	0	107.2
2	S	36.4	Very low	45.8	Very low	124 Å²	124	154.9 Å²	154.9	87%	0.867	85%	0.85	S	S	*	*			trans	-90.8	122.2	179.1	-55.2	0	0	0	0	108.6
3	V	40.5	Very low	46.3	Very low	134 Å²	134	149.3 Å²	149.3	81%	0.812	82%	0.824	S	S	*	*			trans	-86.7	115.8	175.9	-171.2	0	0	0	0	107.4
4	L	44.6	Very low	47	Very low	167 Å²	167	150 Å²	150	87%	0.874	82%	0.823	S	S	*	*	P	Polyproline II helix	trans	-75	118.9	173	-79	160.5	0	0	0	108.9
5	L	44.1	Very low	47.8	Very low	158 Å²	158	152.2 Å²	152.2	83%	0.827	82%	0.816	S	S	*	*	P	Polyproline II helix	trans	-83.1	134.7	168.7	-74.2	165.9	0	0	0	109.5
6	P	51.6	Low	48.2	Very low	115 Å²	115	154.7 Å²	154.7	75%	0.747	82%	0.821	S	S	*	*	P	Polyproline II helix	trans	-71.7	140.2	170.2	28.1	-29.9	0	0	0	111	M8	P6-M8 PolarHBondContact O-N 3.08Å
7	N	48.7	Very low	48.6	Very low	156 Å²	156	152.4 Å²	152.4	83%	0.834	81%	0.808	S	S	*	*	P	Polyproline II helix	trans	-56	123.5	-177.9	-111.3	-5.1	0	0	0	112.6	A9	N7-A9 PolarHBondContact O-N 3.42Å; N7-A9 VanDerWaalsContact O-N 3.08Å
8	M	53.9	Low	49	Very low	196 Å²	196	150.6 Å²	150.6	97%	0.966	80%	0.799	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.3	35	175.5	-72.1	173	67.5	0	0	113.6	P6	P6-M8 PolarHBondContact O-N 3.08Å
9	A	50.3	Low	49.3	Very low	81 Å²	81	149.8 Å²	149.8	67%	0.669	79%	0.79	S	S	*	*	T	Hydrogen-bonded Turn	trans	-108	-1.3	-171.5	0	0	0	0	0	115.1	N7	N7-A9 PolarHBondContact O-N 3.42Å; N7-A9 VanDerWaalsContact O-N 3.08Å
10	D	49.7	Very low	49.5	Very low	148 Å²	148	149.7 Å²	149.7	79%	0.791	79%	0.785	S	S	*	*	S	Bend	trans	-117.7	16.7	-167.5	-148.3	29.6	0	0	0	114.2
11	F	46.9	Very low	49.6	Very low	191 Å²	191	146.4 Å²	146.4	84%	0.838	77%	0.768	S	S	*	*	S	Bend	trans	-108	-16.5	-174.5	-167	-102.8	0	0	0	114.9
12	D	47.1	Very low	50.5	Low	148 Å²	148	140.6 Å²	140.6	79%	0.791	74%	0.738	S	S	*	*			trans	-109.1	23.7	-172.5	-83.3	-16.8	0	0	0	114.5	I14	D12-I14 PolarHBondContact O-N 3.35Å
13	T	52.4	Low	51.5	Low	82 Å²	82	141.6 Å²	141.6	50%	0.503	72%	0.723	S	S	.	*			trans	-90.9	93.8	174.1	-32.4	0	0	0	0	110.3	Y15	T13-Y15 HydrophobicContact CG2-CE2 4.17Å; T13-Y15 PolarHBondContact O-N 2.68Å
14	I	55.5	Low	52.2	Low	159 Å²	159	138.6 Å²	138.6	82%	0.815	71%	0.705	S	S	*	*			trans	-79.5	107.9	167	-57.4	175.5	0	0	0	106.8	D12 E16	D12-I14 PolarHBondContact O-N 3.35Å; I14-E16 PolarHBondContact O-N 3.26Å
15	Y	59.8	Low	52.7	Low	183 Å²	183	133.8 Å²	133.8	72%	0.718	68%	0.682	S	S	*	*	P	Polyproline II helix	trans	-72.4	119.1	172	-67.1	-91.9	0	0	0	108.3	T13 L17	T13-Y15 HydrophobicContact CG2-CE2 4.17Å; T13-Y15 PolarHBondContact O-N 2.68Å; Y15-L17 PolarHBondContact O-N 3.36Å
16	E	53.8	Low	53.2	Low	192 Å²	192	128.3 Å²	128.3	90%	0.897	66%	0.657	S	S	*	*	P	Polyproline II helix	trans	-65	119	167.7	-70	-170.2	164.7	0	0	107.9	I14	I14-E16 PolarHBondContact O-N 3.26Å
17	L	55.2	Low	53.4	Low	115 Å²	115	129.5 Å²	129.5	60%	0.602	65%	0.653	S	S	*	*	P	Polyproline II helix	trans	-88.6	134.6	175.8	-69.3	169.2	0	0	0	108.5	Y15	Y15-L17 PolarHBondContact O-N 3.36Å
18	D	55.5	Low	53.6	Low	121 Å²	121	127.7 Å²	127.7	65%	0.647	64%	0.639	S	S	*	*	P	Polyproline II helix	trans	-64.9	147.6	177.9	-71.4	-39.2	0	0	0	110.9	E20 D21 E22	D18-E20 PolarHBondContact O-N 3.12Å; D18-D21 WeakPolarHBondContact O-CB 3.16Å; D18-D21 PolarHBondContact O-N 3.38Å; D18-E22 PolarHBondContact O-N 3.28Å; D18-E22 VanDerWaalsContact O-N 3.12Å
19	E	55.1	Low	53.4	Low	135 Å²	135	123 Å²	123	63%	0.631	62%	0.615	S	S	*	*	H	α-helix	trans	-57.1	-23.8	-177.9	-72.9	-169.4	-177.9	0	0	114.2	R23	E19-R23 VanDerWaalsContact O-CG 3.27Å; E19-R23 WeakPolarHBondContact O-CG 3.44Å; E19-R23 PolarHBondContact O-N 3.18Å; E19-R23 PolarHBondContact O-NE 3.28Å; E19-R23 IonicContact OE2-NH2 2.58Å; E19-R23 PolarHBondContact OE2-NH2 2.93Å
20	E	52.4	Low	53.5	Low	148 Å²	148	122.2 Å²	122.2	69%	0.692	60%	0.599	S	S	*	*	H	α-helix	trans	-72.8	-39.8	173.7	-73.4	-169.6	155.5	0	0	111.5	D18 R23 V24	D18-E20 PolarHBondContact O-N 3.12Å; E20-R23 PolarHBondContact O-N 3Å; E20-V24 VanDerWaalsContact O-CG2 3.32Å; E20-V24 WeakPolarHBondContact O-CG2 3.41Å; E20-V24 PolarHBondContact O-N 3.24Å
21	D	52.9	Low	53.5	Low	80 Å²	80	120.8 Å²	120.8	43%	0.428	60%	0.595	S	S	.	*	H	α-helix	trans	-68.8	-37.4	176.7	-76.4	-31	0	0	0	111.4	D18 R23 V24 V25	D18-D21 WeakPolarHBondContact O-CB 3.16Å; D18-D21 PolarHBondContact O-N 3.38Å; D21-R23 VanDerWaalsContact C-N 3.3Å; D21-R23 PolarHBondContact O-N 2.95Å; D21-V24 PolarHBondContact O-N 3.18Å; D21-V25 VanDerWaalsContact O-CB 3.31Å; D21-V25 WeakPolarHBondContact O-CB 3.31Å; D21-V25 WeakPolarHBondContact O-CG2 3.05Å; D21-V25 PolarHBondContact O-N 2.72Å
22	E	55.4	Low	53.7	Low	119 Å²	119	118.7 Å²	118.7	56%	0.556	59%	0.586	S	S	*	*	H	α-helix	trans	-60.9	-37.4	170.9	-81.9	-161.6	148.6	0	0	112.8	D18 S26	D18-E22 PolarHBondContact O-N 3.28Å; D18-E22 VanDerWaalsContact O-N 3.12Å; E22-S26 VanDerWaalsContact O-CB 3.3Å; E22-S26 WeakPolarHBondContact O-CB 3.48Å; E22-S26 PolarHBondContact O-N 2.93Å; E22-S26 PolarHBondContact O-OG 3.21Å
23	R	56.1	Low	54.2	Low	146 Å²	146	121.1 Å²	121.1	55%	0.551	59%	0.586	S	S	*	*	H	α-helix	trans	-70.2	-42.9	177.4	-73.2	176	-136	-175	2.2	111.6	E19 E20 D21 S26 E27	E19-R23 VanDerWaalsContact O-CG 3.27Å; E19-R23 WeakPolarHBondContact O-CG 3.44Å; E19-R23 PolarHBondContact O-N 3.18Å; E19-R23 PolarHBondContact O-NE 3.28Å; E19-R23 IonicContact OE2-NH2 2.58Å; E19-R23 PolarHBondContact OE2-NH2 2.93Å; E20-R23 PolarHBondContact O-N 3Å; D21-R23 VanDerWaalsContact C-N 3.3Å; D21-R23 PolarHBondContact O-N 2.95Å; R23-S26 WeakPolarHBondContact O-CB 3.36Å; R23-S26 PolarHBondContact O-N 3.32Å; R23-E27 PolarHBondContact O-N 3.11Å
24	V	56	Low	54.7	Low	70 Å²	70	120.7 Å²	120.7	42%	0.424	59%	0.585	S	S	.	*	H	α-helix	trans	-63.1	-44.7	176.5	173.7	0	0	0	0	110.4	E20 D21 S26 E27 E28	E20-V24 VanDerWaalsContact O-CG2 3.32Å; E20-V24 WeakPolarHBondContact O-CG2 3.41Å; E20-V24 PolarHBondContact O-N 3.24Å; D21-V24 PolarHBondContact O-N 3.18Å; V24-S26 VanDerWaalsContact C-N 3.32Å; V24-S26 PolarHBondContact O-N 3.43Å; V24-E27 PolarHBondContact O-N 2.63Å; V24-E28 HydrophobicContact CG1-CG 4.44Å; V24-E28 WeakPolarHBondContact O-CB 3.33Å; V24-E28 WeakPolarHBondContact O-CG 3.4Å; V24-E28 PolarHBondContact O-N 3.41Å
25	V	54.3	Low	56	Low	66 Å²	66	116.4 Å²	116.4	40%	0.4	57%	0.568	S	S	.	*	H	α-helix	trans	-62.6	-39.5	174.9	173.5	0	0	0	0	110.7	D21 H29	D21-V25 VanDerWaalsContact O-CB 3.31Å; D21-V25 WeakPolarHBondContact O-CB 3.31Å; D21-V25 WeakPolarHBondContact O-CG2 3.05Å; D21-V25 PolarHBondContact O-N 2.72Å; V25-H29 VanDerWaalsContact CG1-ND1 3.35Å; V25-H29 WeakPolarHBondContact CG1-ND1 3.49Å; V25-H29 VanDerWaalsContact O-CB 3.31Å; V25-H29 WeakPolarHBondContact O-CB 3.4Å; V25-H29 PolarHBondContact O-N 2.99Å; V25-H29 PolarHBondContact O-ND1 3.5Å
26	S	56	Low	57.4	Low	43 Å²	43	115.1 Å²	115.1	30%	0.301	57%	0.568	S	S	.	*	H	α-helix	trans	-64.5	-42.2	176	-61.2	0	0	0	0	112.7	E22 R23 V24 L30	E22-S26 VanDerWaalsContact O-CB 3.3Å; E22-S26 WeakPolarHBondContact O-CB 3.48Å; E22-S26 PolarHBondContact O-N 2.93Å; E22-S26 PolarHBondContact O-OG 3.21Å; R23-S26 WeakPolarHBondContact O-CB 3.36Å; R23-S26 PolarHBondContact O-N 3.32Å; V24-S26 VanDerWaalsContact C-N 3.32Å; V24-S26 PolarHBondContact O-N 3.43Å; S26-L30 WeakPolarHBondContact O-CB 3.11Å; S26-L30 WeakPolarHBondContact O-CD1 3.46Å; S26-L30 WeakPolarHBondContact O-CG 3.43Å; S26-L30 PolarHBondContact O-N 2.87Å
27	E	54.8	Low	59.3	Low	140 Å²	140	107.4 Å²	107.4	65%	0.654	54%	0.535	S	S	*	.	H	α-helix	trans	-69.4	-43.9	178	-118.2	175.2	179.8	0	0	111.8	R23 V24 H29 L30 V31	R23-E27 PolarHBondContact O-N 3.11Å; V24-E27 PolarHBondContact O-N 2.63Å; E27-H29 VanDerWaalsContact C-N 3.31Å; E27-H29 PolarHBondContact O-N 2.92Å; E27-L30 PolarHBondContact O-N 3.47Å; E27-V31 VanDerWaalsContact O-CG2 3.31Å; E27-V31 WeakPolarHBondContact O-CG2 3.25Å; E27-V31 PolarHBondContact O-N 3.45Å
28	E	52.1	Low	61.1	Low	118 Å²	118	102.9 Å²	102.9	55%	0.551	51%	0.512	S	S	*	.	H	α-helix	trans	-63.8	-34.5	175	-74.6	-170.2	160.8	0	0	112.7	V24 K32	V24-E28 HydrophobicContact CG1-CG 4.44Å; V24-E28 WeakPolarHBondContact O-CB 3.33Å; V24-E28 WeakPolarHBondContact O-CG 3.4Å; V24-E28 PolarHBondContact O-N 3.41Å; E28-K32 PolarHBondContact O-N 3.12Å
29	H	50.7	Low	63	Low	98 Å²	98	99.8 Å²	99.8	45%	0.454	50%	0.495	S	S	.	.	H	α-helix	trans	-76.6	-29	174.1	-75.9	93	0	0	0	113.3	V25 E27 K32	V25-H29 VanDerWaalsContact CG1-ND1 3.35Å; V25-H29 WeakPolarHBondContact CG1-ND1 3.49Å; V25-H29 VanDerWaalsContact O-CB 3.31Å; V25-H29 WeakPolarHBondContact O-CB 3.4Å; V25-H29 PolarHBondContact O-N 2.99Å; V25-H29 PolarHBondContact O-ND1 3.5Å; E27-H29 VanDerWaalsContact C-N 3.31Å; E27-H29 PolarHBondContact O-N 2.92Å; H29-K32 PolarHBondContact O-N 3.23Å
30	L	52.4	Low	64.9	Low	64 Å²	64	93.9 Å²	93.9	34%	0.335	47%	0.467	S	S	.	.	H	α-helix	trans	-69.1	-38	172.4	-85.6	162	0	0	0	112.2	S26 E27 K32 P168	S26-L30 WeakPolarHBondContact O-CB 3.11Å; S26-L30 WeakPolarHBondContact O-CD1 3.46Å; S26-L30 WeakPolarHBondContact O-CG 3.43Å; S26-L30 PolarHBondContact O-N 2.87Å; E27-L30 PolarHBondContact O-N 3.47Å; L30-K32 PolarHBondContact O-N 2.79Å; L30-P168 HydrophobicContact CD2-CG 4.44Å
31	V	49.1	Very low	66.8	Low	118 Å²	118	89.9 Å²	89.9	72%	0.715	45%	0.446	S	S	*	.	H	α-helix	trans	-66.7	-25.7	175.9	175.5	0	0	0	0	111.8	E27 Y33	E27-V31 VanDerWaalsContact O-CG2 3.31Å; E27-V31 WeakPolarHBondContact O-CG2 3.25Å; E27-V31 PolarHBondContact O-N 3.45Å; V31-Y33 VanDerWaalsContact C-N 3.32Å; V31-Y33 PolarHBondContact O-N 3.11Å
32	K	50.6	Low	68.6	Low	148 Å²	148	87.7 Å²	87.7	64%	0.643	44%	0.442	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.6	-11	-177.6	-92.4	176	179.4	167.1	0	116.3	E28 H29 L30	E28-K32 PolarHBondContact O-N 3.12Å; H29-K32 PolarHBondContact O-N 3.23Å; L30-K32 PolarHBondContact O-N 2.79Å
33	Y	57.7	Low	70.4	Confident	199 Å²	199	84.7 Å²	84.7	78%	0.78	44%	0.437	S	S	*	.	T	Hydrogen-bonded Turn	trans	-117.7	29.3	-173.3	-82.6	-81.4	0	0	0	115	V31 P35	V31-Y33 VanDerWaalsContact C-N 3.32Å; V31-Y33 PolarHBondContact O-N 3.11Å; Y33-P35 WeakPolarHBondContact O-CD 3.13Å
34	C	64.4	Low	71.8	Confident	73 Å²	73	78.7 Å²	78.7	49%	0.493	42%	0.421	S	S	.	.			trans	-94.5	99.8	170.8	-140.5	0	0	0	0	109.9	F163	C34-F163 PolarHBondContact SG-O 2.88Å
35	P	81.8	Confident	73.2	Confident	69 Å²	69	83.5 Å²	83.5	45%	0.448	44%	0.439	S	S	.	.	P	Polyproline II helix	trans	-59.5	150.8	178.9	14.6	-22.4	0	0	0	111.5	Y33 F163	Y33-P35 WeakPolarHBondContact O-CD 3.13Å; P35-F163 HydrophobicContact CB-CD2 3.97Å; P35-F163 HydrophobicContact CB-CE2 4.22Å; P35-F163 HydrophobicContact CB-CG 4.39Å; P35-F163 HydrophobicContact CG-CB 3.74Å; P35-F163 HydrophobicContact CG-CD1 4.05Å; P35-F163 HydrophobicContact CG-CD2 3.61Å; P35-F163 HydrophobicContact CG-CE2 4.18Å; P35-F163 HydrophobicContact CG-CG 3.53Å
36	E	88.9	Confident	74.6	Confident	156 Å²	156	83.2 Å²	83.2	73%	0.729	43%	0.434	S	S	*	.	P	Polyproline II helix	trans	-56.6	135	-178.3	-166.4	177.9	177.8	0	0	110.6	F163	E36-F163 WeakPolarHBondContact O-CE2 3.35Å
37	P	93.1	Very high	76.1	Confident	30 Å²	30	85.2 Å²	85.2	20%	0.195	45%	0.445	C	S	.	.	P	Polyproline II helix	trans	-65.4	141.2	-177.5	27.2	-36.9	0	0	0	111.6	I39 I161 E162	P37-I39 PolarHBondContact O-N 3.29Å; P37-I161 CarbonylContact C-O 3.52Å; P37-I161 VanDerWaalsContact CA-O 3.26Å; P37-I161 WeakPolarHBondContact CA-O 3.31Å; P37-I161 WeakPolarHBondContact CB-O 3.49Å; P37-E162 HydrophobicContact CB-CG 4.03Å
38	V	94.9	Very high	77.5	Confident	20 Å²	20	79 Å²	79	12%	0.121	42%	0.416	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-71.8	127.2	173.5	-177.4	0	0	0	0	108.8	P60 V62 L63 L160 I161 F163	V38-P60 HydrophobicContact CG1-CB 3.69Å; V38-P60 HydrophobicContact CG1-CG 3.87Å; V38-V62 HydrophobicContact CG2-CB 4.13Å; V38-V62 HydrophobicContact CG2-CG1 4.22Å; V38-L63 HydrophobicContact CG2-CD2 4.16Å; V38-L63 HydrophobicContact CG2-CG 4.42Å; V38-L160 WeakPolarHBondContact O-CA 3.46Å; V38-I161 HydrophobicContact CB-CB 4.17Å; V38-I161 PolarHBondContact N-O 3.42Å; V38-I161 PolarHBondContact O-N 3.11Å; V38-F163 HydrophobicContact CG2-CE2 4.24Å; V38-F163 HydrophobicContact CG2-CZ 4.27Å
39	I	94.7	Very high	79.1	Confident	56 Å²	56	78.2 Å²	78.2	29%	0.287	41%	0.411	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-102.2	119.5	-179.3	-50	173.6	0	0	0	109.2	P37 R41 V158 L160	P37-I39 PolarHBondContact O-N 3.29Å; I39-R41 HydrophobicContact CG2-CG 4.22Å; I39-V158 HydrophobicContact CG2-CB 4.04Å; I39-V158 HydrophobicContact CG2-CG1 4.27Å; I39-V158 HydrophobicContact CG2-CG2 4.1Å; I39-L160 HydrophobicContact CB-CD2 4.2Å; I39-L160 HydrophobicContact CG1-CD2 3.74Å; I39-L160 HydrophobicContact CG2-CD2 4.1Å
40	M	94.3	Very high	80.9	Confident	10 Å²	10	74.1 Å²	74.1	5%	0.049	40%	0.396	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-106.5	114.2	172.8	-63.8	179.1	64.4	0	0	110.2	D56 F72 I76 W142 I159 I161	M40-D56 WeakPolarHBondContact CE-O 3.26Å; M40-F72 HydrophobicContact CE-CE1 4.3Å; M40-F72 HydrophobicContact CE-CE2 4.07Å; M40-F72 HydrophobicContact CE-CZ 3.4Å; M40-F72 HydrophobicContact SD-CE2 3.71Å; M40-F72 HydrophobicContact SD-CZ 3.63Å; M40-I76 HydrophobicContact CE-CD1 3.52Å; M40-I76 HydrophobicContact CE-CG1 3.81Å; M40-W142 HydrophobicContact SD-CH2 4.18Å; M40-W142 HydrophobicContact SD-CZ3 4.33Å; M40-I159 HydrophobicContact CB-CB 4.14Å; M40-I159 PolarHBondContact N-O 2.88Å; M40-I159 PolarHBondContact O-N 3.12Å; M40-I159 HydrophobicContact SD-CG2 4.48Å; M40-I161 HydrophobicContact SD-CD1 3.81Å
41	R	92.5	Very high	82.7	Confident	65 Å²	65	71.3 Å²	71.3	25%	0.245	38%	0.381	C	S	.	.			trans	-90.9	164.7	-178.7	-66.9	-172.3	-174.2	-103.5	1.1	112.2	I39 D56 E150 E156 V158	I39-R41 HydrophobicContact CG2-CG 4.22Å; R41-D56 PolarHBondContact O-N 3.39Å; R41-E150 IonicContact CZ-OE1 3.63Å; R41-E150 IonicContact NE-OE1 2.91Å; R41-E150 VanDerWaalsContact NH2-CG 3.33Å; R41-E150 IonicContact NH2-OE1 3.46Å; R41-E150 PolarHBondContact NH2-OE1 3.3Å; R41-E150 IonicContact NH2-OE2 3.91Å; R41-E156 IonicContact CZ-OE1 3.98Å; R41-E156 IonicContact NE-OE1 3.49Å; R41-E156 IonicContact NH1-OE1 2.93Å; R41-E156 PolarHBondContact NH1-OE1 2.87Å; R41-V158 HydrophobicContact CG-CG1 4.01Å
42	G	91.6	Very high	84.7	Confident	34 Å²	34	66 Å²	66	35%	0.351	35%	0.349	S	S	.	.	B	Isolated β-bridge	trans	-68.8	129.7	175	0	0	0	0	0	111.5	K54	G42-K54 CarbonylContact C-O 3.49Å; G42-K54 VanDerWaalsContact CA-O 3.31Å; G42-K54 WeakPolarHBondContact CA-O 3.31Å
43	A	91.7	Very high	86.5	Confident	55 Å²	55	60.1 Å²	60.1	46%	0.455	33%	0.325	S	S	.	.			trans	-110.2	19	175.6	0	0	0	0	0	111.9	K54 D56	A43-K54 PolarHBondContact N-O 2.91Å; A43-D56 HydrophobicContact CB-CB 4.15Å
44	G	85.8	Confident	88.2	Confident	21 Å²	21	55.1 Å²	55.1	22%	0.216	31%	0.307	C	S	.	.			trans	-92.2	153.5	-176.1	0	0	0	0	0	112.9	I46 S52 N53 K54	G44-I46 VanDerWaalsContact C-N 3.35Å; G44-S52 WeakPolarHBondContact CA-OG 3.47Å; G44-S52 PolarHBondContact N-OG 3.37Å; G44-N53 WeakPolarHBondContact CA-OD1 3.34Å; G44-K54 PolarHBondContact N-O 3.38Å
45	H	84.9	Confident	89.6	Confident	171 Å²	171	51.7 Å²	51.7	79%	0.792	28%	0.284	S	S	*	.	S	Bend	trans	-86.3	-6.7	174.3	53.8	-86.5	0	0	0	113
46	I	85.5	Confident	90.2	Very high	59 Å²	59	51.5 Å²	51.5	30%	0.303	28%	0.279	S	S	.	.			trans	-123.3	128.1	178	-50.3	177.2	0	0	0	109.1	G44 V48 N53 L87	G44-I46 VanDerWaalsContact C-N 3.35Å; I46-V48 HydrophobicContact CG2-CG2 4.25Å; I46-N53 HydrophobicContact CB-CB 4.32Å; I46-N53 PolarHBondContact O-N 2.96Å; I46-L87 HydrophobicContact CB-CD2 3.94Å; I46-L87 HydrophobicContact CD1-CD2 3.89Å; I46-L87 HydrophobicContact CG1-CD2 4.46Å; I46-L87 HydrophobicContact CG2-CD2 3.83Å
47	T	86.6	Confident	90.3	Very high	86 Å²	86	46.9 Å²	46.9	53%	0.528	26%	0.261	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-127.5	127.7	176.7	-60.1	0	0	0	0	109.5	L51	T47-L51 WeakPolarHBondContact CA-O 3.4Å
48	V	84.6	Confident	90.4	Very high	8 Å²	8	52.3 Å²	52.3	5%	0.048	28%	0.284	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.5	116.7	178.6	-176.2	0	0	0	0	109	I46 G50 L51 L87 N116	I46-V48 HydrophobicContact CG2-CG2 4.25Å; V48-G50 PolarHBondContact O-N 3.3Å; V48-L51 PolarHBondContact N-O 3.22Å; V48-L51 WeakPolarHBondContact O-CB 3.42Å; V48-L51 PolarHBondContact O-N 3.37Å; V48-L87 HydrophobicContact CG2-CD1 4.47Å; V48-N116 PolarHBondContact O-ND2 3.44Å
49	F	85.7	Confident	90.5	Very high	102 Å²	102	53.9 Å²	53.9	45%	0.447	29%	0.29	S	S	.	.	T	Hydrogen-bonded Turn	trans	47.7	43.9	-173.8	-59.1	-72.4	0	0	0	113.4	L51 V112 I113 N116	F49-L51 VanDerWaalsContact C-N 3.27Å; F49-L51 PolarHBondContact O-N 3.02Å; F49-V112 HydrophobicContact CE2-CB 4.28Å; F49-V112 HydrophobicContact CE2-CG1 3.8Å; F49-V112 HydrophobicContact CZ-CG1 4.49Å; F49-I113 HydrophobicContact CE2-CG1 4.48Å; F49-I113 HydrophobicContact CZ-CG1 4.13Å; F49-N116 HydrophobicContact CD2-CB 3.94Å
50	G	88.9	Confident	90.5	Very high	13 Å²	13	52.3 Å²	52.3	13%	0.134	28%	0.283	C	S	.	.	T	Hydrogen-bonded Turn	trans	79.5	-4.4	-179.6	0	0	0	0	0	115.3	V48 M155 E156 Y157	V48-G50 PolarHBondContact O-N 3.3Å; G50-M155 VanDerWaalsContact CA-O 3.3Å; G50-M155 WeakPolarHBondContact CA-O 3.44Å; G50-E156 CarbonylContact O-C 3.58Å; G50-E156 WeakPolarHBondContact O-CA 3.47Å; G50-Y157 PolarHBondContact O-N 3.5Å
51	L	89.8	Confident	90.5	Very high	4 Å²	4	56.2 Å²	56.2	2%	0.021	31%	0.311	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.4	114.6	175.3	-174.1	65.5	0	0	0	110.1	T47 V48 F49 F55 L83 A119 R120 I123 Y157	T47-L51 WeakPolarHBondContact CA-O 3.4Å; V48-L51 PolarHBondContact N-O 3.22Å; V48-L51 WeakPolarHBondContact O-CB 3.42Å; V48-L51 PolarHBondContact O-N 3.37Å; F49-L51 VanDerWaalsContact C-N 3.27Å; F49-L51 PolarHBondContact O-N 3.02Å; L51-F55 HydrophobicContact CD1-CZ 4.32Å; L51-L83 HydrophobicContact CD1-CD2 4.24Å; L51-L83 HydrophobicContact CD2-CD2 3.96Å; L51-L83 HydrophobicContact CG-CD2 4.01Å; L51-A119 HydrophobicContact CD2-CB 4.24Å; L51-R120 HydrophobicContact CD2-CG 4.15Å; L51-I123 HydrophobicContact CD1-CD1 4.12Å; L51-I123 HydrophobicContact CD2-CD1 4.06Å; L51-Y157 HydrophobicContact CB-CD2 4.13Å; L51-Y157 HydrophobicContact CD1-CG 4.34Å
52	S	90.6	Very high	90.5	Very high	6 Å²	6	57.6 Å²	57.6	4%	0.042	33%	0.327	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-70.3	148	173.7	176.3	0	0	0	0	111.3	G44 K54 L83	G44-S52 WeakPolarHBondContact CA-OG 3.47Å; G44-S52 PolarHBondContact N-OG 3.37Å; S52-K54 PolarHBondContact O-N 3.41Å; S52-K54 PolarHBondContact OG-N 2.96Å; S52-K54 PolarHBondContact OG-O 2.67Å; S52-L83 WeakPolarHBondContact O-CD2 3.3Å
53	N	88.6	Confident	90.7	Very high	25 Å²	25	56 Å²	56	13%	0.134	31%	0.31	C	S	.	.	S	Bend	trans	-75.8	-9.3	175.1	72.3	-10.2	0	0	0	114.8	G44 I46 L83 L87	G44-N53 WeakPolarHBondContact CA-OD1 3.34Å; I46-N53 HydrophobicContact CB-CB 4.32Å; I46-N53 PolarHBondContact O-N 2.96Å; N53-L83 WeakPolarHBondContact O-CB 3.37Å; N53-L87 HydrophobicContact CB-CD1 3.64Å; N53-L87 HydrophobicContact CB-CD2 3.29Å; N53-L87 HydrophobicContact CB-CG 3.99Å
54	K	92.8	Very high	90.8	Very high	95 Å²	95	58 Å²	58	41%	0.413	32%	0.317	S	S	.	.			trans	-149.8	136.4	178.2	-174	-176.2	176.3	-165.2	0	109.4	G42 A43 G44 S52 N80	G42-K54 CarbonylContact C-O 3.49Å; G42-K54 VanDerWaalsContact CA-O 3.31Å; G42-K54 WeakPolarHBondContact CA-O 3.31Å; A43-K54 PolarHBondContact N-O 2.91Å; G44-K54 PolarHBondContact N-O 3.38Å; S52-K54 PolarHBondContact O-N 3.41Å; S52-K54 PolarHBondContact OG-N 2.96Å; S52-K54 PolarHBondContact OG-O 2.67Å; K54-N80 WeakPolarHBondContact CA-OD1 3.48Å
55	F	94.6	Very high	91.1	Very high	0 Å²	0	60.9 Å²	60.9	0%	0	35%	0.347	C	S	.	.	B	Isolated β-bridge	trans	-96.9	152	165	-72.9	-75.3	0	0	0	110.3	L51 I76 V79 N80 L83 L144 Y157 I159	L51-F55 HydrophobicContact CD1-CZ 4.32Å; F55-I76 HydrophobicContact CB-CD1 3.79Å; F55-I76 HydrophobicContact CB-CG1 4.46Å; F55-V79 HydrophobicContact CD2-CG1 3.98Å; F55-V79 HydrophobicContact CE2-CG1 4.36Å; F55-N80 PolarHBondContact N-OD1 3.22Å; F55-N80 PolarHBondContact O-ND2 2.91Å; F55-N80 VanDerWaalsContact O-ND2 3.07Å; F55-L83 HydrophobicContact CD2-CD1 3.55Å; F55-L83 HydrophobicContact CE2-CD1 3.68Å; F55-L144 HydrophobicContact CE2-CD1 4.48Å; F55-L144 HydrophobicContact CZ-CD1 4.01Å; F55-Y157 WeakPolarHBondContact CE1-O 3.37Å; F55-I159 HydrophobicContact CB-CD1 4.31Å; F55-I159 HydrophobicContact CD1-CD1 4.1Å; F55-I159 HydrophobicContact CD1-CG1 4.2Å; F55-I159 HydrophobicContact CD2-CD1 3.58Å; F55-I159 HydrophobicContact CD2-CG1 4.24Å; F55-I159 HydrophobicContact CE1-CD1 4.36Å; F55-I159 HydrophobicContact CE1-CG1 4.05Å; F55-I159 HydrophobicContact CE2-CD1 3.84Å; F55-I159 HydrophobicContact CE2-CG1 4.06Å; F55-I159 HydrophobicContact CG-CD1 3.72Å; F55-I159 HydrophobicContact CG-CG1 4.31Å; F55-I159 HydrophobicContact CZ-CD1 4.23Å; F55-I159 HydrophobicContact CZ-CG1 3.98Å
56	D	93.3	Very high	91.6	Very high	65 Å²	65	57.5 Å²	57.5	35%	0.348	33%	0.33	S	S	.	.			trans	-56	142	175.2	-159.8	-9.6	0	0	0	111.3	M40 R41 A43 E58 I76	M40-D56 WeakPolarHBondContact CE-O 3.26Å; R41-D56 PolarHBondContact O-N 3.39Å; A43-D56 HydrophobicContact CB-CB 4.15Å; D56-E58 PolarHBondContact OD1-N 3.26Å; D56-I76 WeakPolarHBondContact O-CG1 3.31Å
57	T	92.3	Very high	92.1	Very high	59 Å²	59	55.2 Å²	55.2	36%	0.362	32%	0.319	S	S	.	.			trans	-110	-2.3	179.9	55.1	0	0	0	0	112.4	I76 N80	T57-I76 HydrophobicContact CG2-CG1 4.43Å; T57-I76 HydrophobicContact CG2-CG2 4.06Å; T57-N80 WeakPolarHBondContact CG2-ND2 3.4Å
58	E	95.2	Very high	92.5	Very high	145 Å²	145	53.7 Å²	53.7	68%	0.678	32%	0.315	S	S	*	.	S	Bend	trans	-59.2	135.4	171.4	-171.5	171.6	-175.3	0	0	110.5	D56 P60 F72	D56-E58 PolarHBondContact OD1-N 3.26Å; E58-P60 WeakPolarHBondContact O-CD 3.44Å; E58-F72 WeakPolarHBondContact O-CE1 3.3Å
59	F	96	Very high	93.1	Very high	53 Å²	53	56.6 Å²	56.6	23%	0.232	33%	0.333	C	S	.	.	P	Polyproline II helix	trans	-76.7	122.1	-178.9	-179.3	-100.5	0	0	0	110.2	S61 L63 V67 P69 F72	F59-S61 PolarHBondContact O-N 3.13Å; F59-L63 HydrophobicContact CE1-CB 4.47Å; F59-L63 HydrophobicContact CE2-CB 4.25Å; F59-L63 HydrophobicContact CZ-CB 3.83Å; F59-V67 HydrophobicContact CE2-CG1 3.86Å; F59-V67 HydrophobicContact CZ-CG1 4.2Å; F59-P69 HydrophobicContact CD1-CG 4.44Å; F59-P69 HydrophobicContact CD2-CB 4.03Å; F59-P69 HydrophobicContact CD2-CG 4.33Å; F59-P69 HydrophobicContact CE1-CG 4.32Å; F59-P69 HydrophobicContact CE2-CB 4.27Å; F59-P69 HydrophobicContact CE2-CG 4.21Å; F59-P69 HydrophobicContact CG-CB 4.26Å; F59-P69 HydrophobicContact CG-CG 4.43Å; F59-P69 HydrophobicContact CZ-CG 4.2Å; F59-F72 HydrophobicContact CD2-CB 3.84Å; F59-F72 AromaticContact CD2-CD1 3.78Å; F59-F72 HydrophobicContact CD2-CD1 3.78Å; F59-F72 HydrophobicContact CD2-CD2 4.39Å; F59-F72 HydrophobicContact CD2-CE1 4.45Å; F59-F72 AromaticContact CD2-CG 3.74Å; F59-F72 HydrophobicContact CD2-CG 3.74Å; F59-F72 HydrophobicContact CE2-CB 3.89Å; F59-F72 HydrophobicContact CE2-CG 4.11Å
60	P	94.9	Very high	93.6	Very high	22 Å²	22	57.7 Å²	57.7	14%	0.143	34%	0.34	C	S	.	.	P	Polyproline II helix	trans	-69.7	120.1	178.5	-15.7	28.9	0	0	0	110.8	V38 E58 V62 L63 F72	V38-P60 HydrophobicContact CG1-CB 3.69Å; V38-P60 HydrophobicContact CG1-CG 3.87Å; E58-P60 WeakPolarHBondContact O-CD 3.44Å; P60-V62 PolarHBondContact O-N 2.62Å; P60-V62 VanDerWaalsContact O-N 3.12Å; P60-L63 HydrophobicContact CB-CD1 4.17Å; P60-L63 HydrophobicContact CB-CG 4.18Å; P60-L63 HydrophobicContact CG-CD1 3.9Å; P60-L63 HydrophobicContact CG-CG 4.46Å; P60-L63 WeakPolarHBondContact O-CB 3.46Å; P60-L63 PolarHBondContact O-N 3.4Å; P60-F72 HydrophobicContact CG-CE2 4.01Å; P60-F72 HydrophobicContact CG-CZ 3.93Å
61	S	94.3	Very high	94	Very high	93 Å²	93	60.4 Å²	60.4	65%	0.65	35%	0.349	S	S	*	.	G	3₁₀ helix	trans	-57.4	-29.3	-178.9	58.2	0	0	0	0	113.4	F59 L63 T64	F59-S61 PolarHBondContact O-N 3.13Å; S61-L63 PolarHBondContact O-N 3.25Å; S61-T64 WeakPolarHBondContact O-CB 3.45Å; S61-T64 PolarHBondContact O-N 2.83Å; S61-T64 PolarHBondContact O-OG1 2.8Å
62	V	93.3	Very high	94.4	Very high	93 Å²	93	60.3 Å²	60.3	56%	0.564	35%	0.349	S	S	*	.	G	3₁₀ helix	trans	-60.9	-23.3	175.7	-172.4	0	0	0	0	112.5	V38 P60 T64 F163	V38-V62 HydrophobicContact CG2-CB 4.13Å; V38-V62 HydrophobicContact CG2-CG1 4.22Å; P60-V62 PolarHBondContact O-N 2.62Å; P60-V62 VanDerWaalsContact O-N 3.12Å; V62-T64 VanDerWaalsContact C-N 3.33Å; V62-F163 HydrophobicContact CG1-CZ 4.02Å
63	L	94.5	Very high	94.7	Very high	0 Å²	0	65.5 Å²	65.5	0%	0	37%	0.37	C	S	.	.	G	3₁₀ helix	trans	-88.3	-0.1	177.6	-58.5	179.1	0	0	0	113.4	V38 F59 P60 S61 G65 K66 V67 F72 L140 I161 F163	V38-L63 HydrophobicContact CG2-CD2 4.16Å; V38-L63 HydrophobicContact CG2-CG 4.42Å; F59-L63 HydrophobicContact CE1-CB 4.47Å; F59-L63 HydrophobicContact CE2-CB 4.25Å; F59-L63 HydrophobicContact CZ-CB 3.83Å; P60-L63 HydrophobicContact CB-CD1 4.17Å; P60-L63 HydrophobicContact CB-CG 4.18Å; P60-L63 HydrophobicContact CG-CD1 3.9Å; P60-L63 HydrophobicContact CG-CG 4.46Å; P60-L63 WeakPolarHBondContact O-CB 3.46Å; P60-L63 PolarHBondContact O-N 3.4Å; S61-L63 PolarHBondContact O-N 3.25Å; L63-G65 PolarHBondContact O-N 3Å; L63-K66 WeakPolarHBondContact O-CB 3.06Å; L63-K66 PolarHBondContact O-N 2.82Å; L63-V67 HydrophobicContact CB-CG1 3.95Å; L63-V67 HydrophobicContact CD1-CG1 4.27Å; L63-V67 PolarHBondContact O-N 2.89Å; L63-F72 HydrophobicContact CD1-CD2 4.06Å; L63-F72 HydrophobicContact CD1-CE2 4.09Å; L63-L140 HydrophobicContact CD2-CD1 4.27Å; L63-L140 HydrophobicContact CD2-CD2 4.22Å; L63-I161 HydrophobicContact CD1-CD1 3.71Å; L63-I161 HydrophobicContact CD2-CG2 4.22Å; L63-F163 HydrophobicContact CD2-CE1 4.41Å; L63-F163 HydrophobicContact CD2-CZ 4.2Å
64	T	94.3	Very high	95.1	Very high	97 Å²	97	66.9 Å²	66.9	60%	0.595	38%	0.38	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.5	131.7	177.4	-56.4	0	0	0	0	110.3	S61 V62 K66	S61-T64 WeakPolarHBondContact O-CB 3.45Å; S61-T64 PolarHBondContact O-N 2.83Å; S61-T64 PolarHBondContact O-OG1 2.8Å; V62-T64 VanDerWaalsContact C-N 3.33Å; T64-K66 PolarHBondContact O-N 2.85Å
65	G	93.4	Very high	95.3	Very high	82 Å²	82	62.4 Å²	62.4	85%	0.845	36%	0.361	S	S	*	.	T	Hydrogen-bonded Turn	trans	75.4	-1.8	-175.4	0	0	0	0	0	115	L63	L63-G65 PolarHBondContact O-N 3Å
66	K	93.5	Very high	95.4	Very high	101 Å²	101	62.4 Å²	62.4	44%	0.439	36%	0.361	S	S	.	.	T	Hydrogen-bonded Turn	trans	-104.8	-42.3	174.8	-60.6	-66.3	-176	118.1	0	112.7	L63 T64 L140	L63-K66 WeakPolarHBondContact O-CB 3.06Å; L63-K66 PolarHBondContact O-N 2.82Å; T64-K66 PolarHBondContact O-N 2.85Å; K66-L140 HydrophobicContact CB-CD1 4.36Å
67	V	96.6	Very high	95.6	Very high	11 Å²	11	62 Å²	62	7%	0.067	36%	0.363	C	S	.	.	S	Bend	trans	-136.8	145.1	177.7	70.4	0	0	0	0	110	F59 L63 E71 F72 L134 Y135 L138	F59-V67 HydrophobicContact CE2-CG1 3.86Å; F59-V67 HydrophobicContact CZ-CG1 4.2Å; L63-V67 HydrophobicContact CB-CG1 3.95Å; L63-V67 HydrophobicContact CD1-CG1 4.27Å; L63-V67 PolarHBondContact O-N 2.89Å; V67-E71 HydrophobicContact CG2-CB 4.15Å; V67-F72 HydrophobicContact CG1-CB 4.37Å; V67-L134 HydrophobicContact CG2-CD2 4.38Å; V67-Y135 HydrophobicContact CB-CE1 4.5Å; V67-Y135 HydrophobicContact CG2-CE1 3.92Å; V67-L138 HydrophobicContact CB-CD1 3.89Å; V67-L138 HydrophobicContact CG2-CD1 3.72Å
68	A	96.4	Very high	95.7	Very high	54 Å²	54	63.5 Å²	63.5	45%	0.446	36%	0.362	S	S	.	.			trans	-67.8	136.7	174	0	0	0	0	0	110.4	E70 E71 F72	A68-E70 PolarHBondContact O-N 3.37Å; A68-E71 HydrophobicContact CB-CB 4.48Å; A68-E71 HydrophobicContact CB-CG 4.4Å; A68-E71 PolarHBondContact O-N 3.33Å; A68-E71 VanDerWaalsContact O-N 3.12Å; A68-F72 PolarHBondContact O-N 2.81Å; A68-F72 VanDerWaalsContact O-N 3.11Å
69	P	96.9	Very high	95.7	Very high	68 Å²	68	56.7 Å²	56.7	44%	0.442	33%	0.33	S	S	.	.	H	α-helix	trans	-55	-34.7	177.8	-28.2	35.5	0	0	0	113.8	F59 F72 K73	F59-P69 HydrophobicContact CD1-CG 4.44Å; F59-P69 HydrophobicContact CD2-CB 4.03Å; F59-P69 HydrophobicContact CD2-CG 4.33Å; F59-P69 HydrophobicContact CE1-CG 4.32Å; F59-P69 HydrophobicContact CE2-CB 4.27Å; F59-P69 HydrophobicContact CE2-CG 4.21Å; F59-P69 HydrophobicContact CG-CB 4.26Å; F59-P69 HydrophobicContact CG-CG 4.43Å; F59-P69 HydrophobicContact CZ-CG 4.2Å; P69-F72 PolarHBondContact O-N 2.85Å; P69-K73 VanDerWaalsContact O-CB 3.25Å; P69-K73 WeakPolarHBondContact O-CB 3.46Å; P69-K73 PolarHBondContact O-N 3.34Å
70	E	96.6	Very high	95.7	Very high	125 Å²	125	55.2 Å²	55.2	58%	0.584	33%	0.325	S	S	*	.	H	α-helix	trans	-69.5	-37.3	179.1	-60.2	-51.9	139.6	0	0	113.2	A68 K73 T74	A68-E70 PolarHBondContact O-N 3.37Å; E70-K73 PolarHBondContact O-N 2.85Å; E70-T74 WeakPolarHBondContact O-CB 3.44Å; E70-T74 PolarHBondContact O-N 3.05Å; E70-T74 PolarHBondContact O-OG1 3.24Å
71	E	96.8	Very high	95.6	Very high	71 Å²	71	56.4 Å²	56.4	33%	0.332	34%	0.336	S	S	.	.	H	α-helix	trans	-68	-43.9	174.6	-75.7	-64.1	155.1	0	0	110.6	V67 A68 K73 T74 S75 R133 L134	V67-E71 HydrophobicContact CG2-CB 4.15Å; A68-E71 HydrophobicContact CB-CB 4.48Å; A68-E71 HydrophobicContact CB-CG 4.4Å; A68-E71 PolarHBondContact O-N 3.33Å; A68-E71 VanDerWaalsContact O-N 3.12Å; E71-K73 PolarHBondContact O-N 3.17Å; E71-T74 PolarHBondContact O-N 3.24Å; E71-S75 PolarHBondContact O-N 3.48Å; E71-S75 PolarHBondContact O-OG 2.96Å; E71-S75 VanDerWaalsContact O-OG 3.14Å; E71-R133 IonicContact OE2-CZ 3.8Å; E71-R133 IonicContact OE2-NH1 3.02Å; E71-R133 PolarHBondContact OE2-NH1 3.07Å; E71-R133 IonicContact OE2-NH2 2.63Å; E71-R133 PolarHBondContact OE2-NH2 3.27Å; E71-L134 HydrophobicContact CB-CD2 3.81Å; E71-L134 HydrophobicContact CG-CD2 4.02Å
72	F	97.3	Very high	95.5	Very high	1 Å²	1	52.9 Å²	52.9	0%	0.004	31%	0.312	C	S	.	.	H	α-helix	trans	-55.7	-52.3	173.5	174.6	-89.5	0	0	0	111.3	M40 E58 F59 P60 L63 V67 A68 P69 T74 S75 I76 W142 I161	M40-F72 HydrophobicContact CE-CE1 4.3Å; M40-F72 HydrophobicContact CE-CE2 4.07Å; M40-F72 HydrophobicContact CE-CZ 3.4Å; M40-F72 HydrophobicContact SD-CE2 3.71Å; M40-F72 HydrophobicContact SD-CZ 3.63Å; E58-F72 WeakPolarHBondContact O-CE1 3.3Å; F59-F72 HydrophobicContact CD2-CB 3.84Å; F59-F72 AromaticContact CD2-CD1 3.78Å; F59-F72 HydrophobicContact CD2-CD1 3.78Å; F59-F72 HydrophobicContact CD2-CD2 4.39Å; F59-F72 HydrophobicContact CD2-CE1 4.45Å; F59-F72 AromaticContact CD2-CG 3.74Å; F59-F72 HydrophobicContact CD2-CG 3.74Å; F59-F72 HydrophobicContact CE2-CB 3.89Å; F59-F72 HydrophobicContact CE2-CG 4.11Å; P60-F72 HydrophobicContact CG-CE2 4.01Å; P60-F72 HydrophobicContact CG-CZ 3.93Å; L63-F72 HydrophobicContact CD1-CD2 4.06Å; L63-F72 HydrophobicContact CD1-CE2 4.09Å; V67-F72 HydrophobicContact CG1-CB 4.37Å; A68-F72 PolarHBondContact O-N 2.81Å; A68-F72 VanDerWaalsContact O-N 3.11Å; P69-F72 PolarHBondContact O-N 2.85Å; F72-T74 VanDerWaalsContact C-N 3.26Å; F72-T74 PolarHBondContact O-N 2.69Å; F72-S75 PolarHBondContact O-N 3.42Å; F72-I76 HydrophobicContact CD1-CG2 4.45Å; F72-I76 HydrophobicContact CE1-CG2 4.24Å; F72-I76 WeakPolarHBondContact O-CG2 3.3Å; F72-I76 PolarHBondContact O-N 3.2Å; F72-W142 AromaticContact CD2-CH2 3.73Å; F72-W142 HydrophobicContact CD2-CH2 3.73Å; F72-W142 AromaticContact CD2-CZ2 3.53Å; F72-W142 HydrophobicContact CD2-CZ2 3.53Å; F72-W142 AromaticContact CE2-CH2 3.54Å; F72-W142 HydrophobicContact CE2-CH2 3.54Å; F72-W142 AromaticContact CE2-CZ2 3.61Å; F72-W142 HydrophobicContact CE2-CZ2 3.61Å; F72-W142 HydrophobicContact CZ-CH2 4.33Å; F72-I161 HydrophobicContact CE2-CD1 4.02Å
73	K	96.9	Very high	95.2	Very high	115 Å²	115	48.6 Å²	48.6	50%	0.5	29%	0.285	S	S	.	.	H	α-helix	trans	-59.1	-38.7	179.6	-173.1	176.9	-179.8	-178.3	0	111.6	P69 E70 E71 I76 S77	P69-K73 VanDerWaalsContact O-CB 3.25Å; P69-K73 WeakPolarHBondContact O-CB 3.46Å; P69-K73 PolarHBondContact O-N 3.34Å; E70-K73 PolarHBondContact O-N 2.85Å; E71-K73 PolarHBondContact O-N 3.17Å; K73-I76 WeakPolarHBondContact O-CG2 3.39Å; K73-S77 WeakPolarHBondContact O-CB 3.42Å; K73-S77 PolarHBondContact O-N 3.29Å; K73-S77 PolarHBondContact O-OG 3.36Å
74	T	97.3	Very high	94.8	Very high	55 Å²	55	56.5 Å²	56.5	34%	0.337	32%	0.32	S	S	.	.	H	α-helix	trans	-65.3	-49.1	176	-62.7	0	0	0	0	111.6	E70 E71 F72 S77 R78	E70-T74 WeakPolarHBondContact O-CB 3.44Å; E70-T74 PolarHBondContact O-N 3.05Å; E70-T74 PolarHBondContact O-OG1 3.24Å; E71-T74 PolarHBondContact O-N 3.24Å; F72-T74 VanDerWaalsContact C-N 3.26Å; F72-T74 PolarHBondContact O-N 2.69Å; T74-S77 PolarHBondContact O-N 3.33Å; T74-R78 WeakPolarHBondContact O-CG 3.37Å; T74-R78 PolarHBondContact O-N 3.28Å
75	S	97.2	Very high	94.2	Very high	1 Å²	1	60 Å²	60	1%	0.007	33%	0.327	C	S	.	.	H	α-helix	trans	-60.4	-49.4	179.2	-58.1	0	0	0	0	111.6	E71 F72 S77 R78 V79 E130 Y135	E71-S75 PolarHBondContact O-N 3.48Å; E71-S75 PolarHBondContact O-OG 2.96Å; E71-S75 VanDerWaalsContact O-OG 3.14Å; F72-S75 PolarHBondContact O-N 3.42Å; S75-S77 VanDerWaalsContact C-N 3.31Å; S75-S77 PolarHBondContact O-N 3.03Å; S75-R78 WeakPolarHBondContact O-CB 3.41Å; S75-R78 PolarHBondContact O-N 2.86Å; S75-V79 PolarHBondContact O-N 2.89Å; S75-V79 VanDerWaalsContact O-N 3.15Å; S75-E130 VanDerWaalsContact OG-CD 3.24Å; S75-E130 PolarHBondContact OG-OE2 3.01Å; S75-Y135 WeakPolarHBondContact CB-OH 3.33Å; S75-Y135 WeakPolarHBondContact OG-CE2 3.37Å; S75-Y135 PolarHBondContact OG-OH 3.33Å
76	I	96.8	Very high	93.2	Very high	0 Å²	0	57.9 Å²	57.9	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-67.3	-33.1	179.8	-164.3	63.5	0	0	0	112.1	M40 F55 D56 T57 F72 K73 R78 V79 N80 W142 I159	M40-I76 HydrophobicContact CE-CD1 3.52Å; M40-I76 HydrophobicContact CE-CG1 3.81Å; F55-I76 HydrophobicContact CB-CD1 3.79Å; F55-I76 HydrophobicContact CB-CG1 4.46Å; D56-I76 WeakPolarHBondContact O-CG1 3.31Å; T57-I76 HydrophobicContact CG2-CG1 4.43Å; T57-I76 HydrophobicContact CG2-CG2 4.06Å; F72-I76 HydrophobicContact CD1-CG2 4.45Å; F72-I76 HydrophobicContact CE1-CG2 4.24Å; F72-I76 WeakPolarHBondContact O-CG2 3.3Å; F72-I76 PolarHBondContact O-N 3.2Å; K73-I76 WeakPolarHBondContact O-CG2 3.39Å; I76-R78 VanDerWaalsContact C-N 3.35Å; I76-R78 PolarHBondContact O-N 3.32Å; I76-V79 HydrophobicContact CD1-CB 4.43Å; I76-V79 WeakPolarHBondContact O-CB 3.5Å; I76-V79 PolarHBondContact O-N 2.97Å; I76-N80 WeakPolarHBondContact O-CB 3.33Å; I76-N80 PolarHBondContact O-N 3.39Å; I76-W142 HydrophobicContact CB-CH2 4.5Å; I76-W142 HydrophobicContact CD1-CZ3 4.17Å; I76-I159 HydrophobicContact CD1-CD1 3.85Å
77	S	96.4	Very high	92.1	Very high	56 Å²	56	53.8 Å²	53.8	39%	0.392	28%	0.279	S	S	.	.	H	α-helix	trans	-64.4	-38.3	174.5	-66.1	0	0	0	0	112	K73 T74 S75 N80 A81	K73-S77 WeakPolarHBondContact O-CB 3.42Å; K73-S77 PolarHBondContact O-N 3.29Å; K73-S77 PolarHBondContact O-OG 3.36Å; T74-S77 PolarHBondContact O-N 3.33Å; S75-S77 VanDerWaalsContact C-N 3.31Å; S75-S77 PolarHBondContact O-N 3.03Å; S77-N80 PolarHBondContact O-N 3.4Å; S77-A81 WeakPolarHBondContact O-CB 3.44Å; S77-A81 PolarHBondContact O-N 3.18Å
78	R	95.6	Very high	90.8	Very high	91 Å²	91	56.7 Å²	56.7	34%	0.343	30%	0.298	S	S	.	.	H	α-helix	trans	-63.9	-41.2	173.2	-71.2	173.1	-178	147.7	3.1	111.6	T74 S75 I76 A81 C82 L126 E130	T74-R78 WeakPolarHBondContact O-CG 3.37Å; T74-R78 PolarHBondContact O-N 3.28Å; S75-R78 WeakPolarHBondContact O-CB 3.41Å; S75-R78 PolarHBondContact O-N 2.86Å; I76-R78 VanDerWaalsContact C-N 3.35Å; I76-R78 PolarHBondContact O-N 3.32Å; R78-A81 PolarHBondContact O-N 2.97Å; R78-C82 PolarHBondContact O-N 3.14Å; R78-L126 HydrophobicContact CB-CD1 4.46Å; R78-L126 HydrophobicContact CB-CD2 4.14Å; R78-E130 VanDerWaalsContact CD-OE1 3.28Å; R78-E130 WeakPolarHBondContact CD-OE1 3.48Å; R78-E130 IonicContact CZ-OE1 3.68Å; R78-E130 IonicContact NE-OE1 3.9Å; R78-E130 IonicContact NH1-OE1 2.7Å; R78-E130 PolarHBondContact NH1-OE1 3.07Å; R78-E130 IonicContact NH1-OE2 3.74Å
79	V	95.8	Very high	89.8	Confident	1 Å²	1	57.4 Å²	57.4	1%	0.006	30%	0.297	C	S	.	.	H	α-helix	trans	-61.2	-49.6	174.9	175.5	0	0	0	0	110.8	F55 S75 I76 A81 C82 L83 I123 L126 L127 I159	F55-V79 HydrophobicContact CD2-CG1 3.98Å; F55-V79 HydrophobicContact CE2-CG1 4.36Å; S75-V79 PolarHBondContact O-N 2.89Å; S75-V79 VanDerWaalsContact O-N 3.15Å; I76-V79 HydrophobicContact CD1-CB 4.43Å; I76-V79 WeakPolarHBondContact O-CB 3.5Å; I76-V79 PolarHBondContact O-N 2.97Å; V79-A81 VanDerWaalsContact C-N 3.3Å; V79-A81 PolarHBondContact O-N 3.22Å; V79-C82 WeakPolarHBondContact O-CB 3.42Å; V79-C82 PolarHBondContact O-N 3.05Å; V79-C82 VanDerWaalsContact O-N 3.1Å; V79-L83 HydrophobicContact CG1-CD1 4.24Å; V79-L83 PolarHBondContact O-N 2.65Å; V79-I123 HydrophobicContact CG1-CG2 4.21Å; V79-L126 HydrophobicContact CB-CD2 4.36Å; V79-L126 HydrophobicContact CG2-CD2 3.84Å; V79-L126 HydrophobicContact CG2-CG 4.49Å; V79-L127 HydrophobicContact CG2-CD2 3.87Å; V79-I159 HydrophobicContact CG1-CD1 4.04Å
80	N	94.6	Very high	88.6	Confident	23 Å²	23	54.4 Å²	54.4	12%	0.123	28%	0.277	C	S	.	.	H	α-helix	trans	-62.6	-35.9	178.1	-77	-26.5	0	0	0	112.5	K54 F55 T57 I76 S77 L83 K84	K54-N80 WeakPolarHBondContact CA-OD1 3.48Å; F55-N80 PolarHBondContact N-OD1 3.22Å; F55-N80 PolarHBondContact O-ND2 2.91Å; F55-N80 VanDerWaalsContact O-ND2 3.07Å; T57-N80 WeakPolarHBondContact CG2-ND2 3.4Å; I76-N80 WeakPolarHBondContact O-CB 3.33Å; I76-N80 PolarHBondContact O-N 3.39Å; S77-N80 PolarHBondContact O-N 3.4Å; N80-L83 PolarHBondContact O-N 3.32Å; N80-K84 WeakPolarHBondContact O-CB 3.34Å; N80-K84 PolarHBondContact O-N 2.93Å
81	A	93.4	Very high	87.6	Confident	47 Å²	47	50.7 Å²	50.7	39%	0.388	26%	0.262	S	S	.	.	H	α-helix	trans	-65.7	-39.2	173.1	0	0	0	0	0	112.3	S77 R78 V79 K85	S77-A81 WeakPolarHBondContact O-CB 3.44Å; S77-A81 PolarHBondContact O-N 3.18Å; R78-A81 PolarHBondContact O-N 2.97Å; V79-A81 VanDerWaalsContact C-N 3.3Å; V79-A81 PolarHBondContact O-N 3.22Å; A81-K85 WeakPolarHBondContact O-CG 3.13Å; A81-K85 PolarHBondContact O-N 3.15Å
82	C	91.1	Very high	86.9	Confident	19 Å²	19	54.8 Å²	54.8	13%	0.128	28%	0.279	C	S	.	.	H	α-helix	trans	-62.2	-45.2	174.1	-173.9	0	0	0	0	111.3	R78 V79 K85 N86 S122 L126	R78-C82 PolarHBondContact O-N 3.14Å; V79-C82 WeakPolarHBondContact O-CB 3.42Å; V79-C82 PolarHBondContact O-N 3.05Å; V79-C82 VanDerWaalsContact O-N 3.1Å; C82-K85 PolarHBondContact O-N 2.91Å; C82-N86 PolarHBondContact O-N 3.49Å; C82-N86 PolarHBondContact O-ND2 2.89Å; C82-S122 PolarHBondContact SG-OG 2.93Å; C82-L126 HydrophobicContact CB-CD2 4.27Å
83	L	88.9	Confident	86	Confident	3 Å²	3	60.9 Å²	60.9	2%	0.016	30%	0.302	C	S	.	.	H	α-helix	trans	-60.3	-49.2	176.6	-76.6	166.7	0	0	0	112.2	L51 S52 N53 F55 V79 N80 K85 N86 L87 I123	L51-L83 HydrophobicContact CD1-CD2 4.24Å; L51-L83 HydrophobicContact CD2-CD2 3.96Å; L51-L83 HydrophobicContact CG-CD2 4.01Å; S52-L83 WeakPolarHBondContact O-CD2 3.3Å; N53-L83 WeakPolarHBondContact O-CB 3.37Å; F55-L83 HydrophobicContact CD2-CD1 3.55Å; F55-L83 HydrophobicContact CE2-CD1 3.68Å; V79-L83 HydrophobicContact CG1-CD1 4.24Å; V79-L83 PolarHBondContact O-N 2.65Å; N80-L83 PolarHBondContact O-N 3.32Å; L83-K85 PolarHBondContact O-N 2.91Å; L83-N86 PolarHBondContact O-N 2.83Å; L83-N86 VanDerWaalsContact O-N 3.12Å; L83-L87 PolarHBondContact O-N 3.21Å; L83-L87 VanDerWaalsContact O-N 3.09Å; L83-I123 HydrophobicContact CD2-CD1 3.41Å; L83-I123 VanDerWaalsContact CD2-CD1 3.41Å; L83-I123 HydrophobicContact CD2-CG1 4.46Å; L83-I123 HydrophobicContact CG-CD1 3.93Å
84	K	85	Confident	85	Confident	166 Å²	166	58.2 Å²	58.2	72%	0.722	29%	0.293	S	S	*	.	H	α-helix	trans	-59.3	-33.3	-179	-168.9	175	-178.2	179.9	0	112.9	N80 P88	N80-K84 WeakPolarHBondContact O-CB 3.34Å; N80-K84 PolarHBondContact O-N 2.93Å; K84-P88 WeakPolarHBondContact O-CD 3.49Å
85	K	81.7	Confident	84.1	Confident	170 Å²	170	61.2 Å²	61.2	74%	0.739	31%	0.306	S	S	*	.	H	α-helix	trans	-72.6	-35	177.5	-72.8	177.2	-179.2	-177.7	0	113.3	A81 C82 L83	A81-K85 WeakPolarHBondContact O-CG 3.13Å; A81-K85 PolarHBondContact O-N 3.15Å; C82-K85 PolarHBondContact O-N 2.91Å; L83-K85 PolarHBondContact O-N 2.91Å
86	N	71.9	Confident	83.1	Confident	37 Å²	37	64.5 Å²	64.5	20%	0.198	33%	0.329	C	S	.	.	H	α-helix	trans	-85.9	-26.6	-175.7	-73.1	-76.7	0	0	0	113.1	C82 L83 N90 A119	C82-N86 PolarHBondContact O-N 3.49Å; C82-N86 PolarHBondContact O-ND2 2.89Å; L83-N86 PolarHBondContact O-N 2.83Å; L83-N86 VanDerWaalsContact O-N 3.12Å; N86-N90 PolarHBondContact O-N 3.45Å; N86-N90 PolarHBondContact O-ND2 3.04Å; N86-N90 PolarHBondContact O-OD1 2.87Å; N86-A119 HydrophobicContact CB-CB 4.09Å
87	L	70.6	Confident	82.1	Confident	15 Å²	15	64.8 Å²	64.8	8%	0.079	33%	0.332	C	S	.	.	H	α-helix	trans	-67.4	-43.4	-169.8	-148.5	90.2	0	0	0	116.1	I46 V48 N53 L83 V89 N90 V91	I46-L87 HydrophobicContact CB-CD2 3.94Å; I46-L87 HydrophobicContact CD1-CD2 3.89Å; I46-L87 HydrophobicContact CG1-CD2 4.46Å; I46-L87 HydrophobicContact CG2-CD2 3.83Å; V48-L87 HydrophobicContact CG2-CD1 4.47Å; N53-L87 HydrophobicContact CB-CD1 3.64Å; N53-L87 HydrophobicContact CB-CD2 3.29Å; N53-L87 HydrophobicContact CB-CG 3.99Å; L83-L87 PolarHBondContact O-N 3.21Å; L83-L87 VanDerWaalsContact O-N 3.09Å; L87-V89 PolarHBondContact O-N 2.97Å; L87-N90 PolarHBondContact O-N 3.02Å; L87-N90 VanDerWaalsContact O-N 3.11Å; L87-V91 HydrophobicContact CG-CG2 4.43Å; L87-V91 WeakPolarHBondContact O-CG2 3.47Å; L87-V91 PolarHBondContact O-N 3.26Å
88	P	70.4	Confident	81	Confident	73 Å²	73	66 Å²	66	47%	0.474	34%	0.339	S	S	.	.	H	α-helix	trans	-62.8	-34	-177.8	-20.6	31.2	0	0	0	112.3	K84 K92	K84-P88 WeakPolarHBondContact O-CD 3.49Å; P88-K92 VanDerWaalsContact O-CG 3.3Å; P88-K92 WeakPolarHBondContact O-CG 3.09Å; P88-K92 PolarHBondContact O-N 2.8Å; P88-K92 VanDerWaalsContact O-N 3.15Å
89	V	74.9	Confident	80	Confident	69 Å²	69	68.8 Å²	68.8	42%	0.418	36%	0.36	S	S	.	.	H	α-helix	trans	-65.9	-51.8	173.9	-179.7	0	0	0	0	108.8	L87 V91 K92 W93 L115	L87-V89 PolarHBondContact O-N 2.97Å; V89-V91 VanDerWaalsContact C-N 3.31Å; V89-V91 PolarHBondContact O-N 3.32Å; V89-K92 PolarHBondContact O-N 2.58Å; V89-W93 PolarHBondContact O-N 2.71Å; V89-L115 HydrophobicContact CG1-CD1 4.41Å; V89-L115 HydrophobicContact CG1-CD2 4.33Å
90	N	72.1	Confident	78.5	Confident	5 Å²	5	71.9 Å²	71.9	3%	0.027	38%	0.381	C	S	.	.	H	α-helix	trans	-57.2	-41.5	-179.7	-62.2	-5.1	0	0	0	113	N86 L87 L94 L115	N86-N90 PolarHBondContact O-N 3.45Å; N86-N90 PolarHBondContact O-ND2 3.04Å; N86-N90 PolarHBondContact O-OD1 2.87Å; L87-N90 PolarHBondContact O-N 3.02Å; L87-N90 VanDerWaalsContact O-N 3.11Å; N90-L94 WeakPolarHBondContact O-CB 3.32Å; N90-L94 PolarHBondContact O-N 2.81Å; N90-L115 WeakPolarHBondContact OD1-CB 3.43Å
91	V	76.1	Confident	76.9	Confident	46 Å²	46	73 Å²	73	28%	0.279	39%	0.39	S	S	.	.	H	α-helix	trans	-68.1	-43.9	179.2	174.5	0	0	0	0	111.5	L87 V89 W93 L94 L95	L87-V91 HydrophobicContact CG-CG2 4.43Å; L87-V91 WeakPolarHBondContact O-CG2 3.47Å; L87-V91 PolarHBondContact O-N 3.26Å; V89-V91 VanDerWaalsContact C-N 3.31Å; V89-V91 PolarHBondContact O-N 3.32Å; V91-W93 VanDerWaalsContact C-N 3.31Å; V91-W93 PolarHBondContact O-N 3.02Å; V91-L94 PolarHBondContact O-N 2.82Å; V91-L95 HydrophobicContact CG1-CD1 4.06Å; V91-L95 HydrophobicContact CG1-CG 4.39Å; V91-L95 WeakPolarHBondContact O-CG 3.38Å; V91-L95 PolarHBondContact O-N 2.85Å
92	K	80	Confident	75.3	Confident	158 Å²	158	76.6 Å²	76.6	69%	0.687	41%	0.411	S	S	*	.	H	α-helix	trans	-59.1	-43.3	176.2	-75.8	178.5	178.7	-175.7	0	111.9	P88 V89 C96	P88-K92 VanDerWaalsContact O-CG 3.3Å; P88-K92 WeakPolarHBondContact O-CG 3.09Å; P88-K92 PolarHBondContact O-N 2.8Å; P88-K92 VanDerWaalsContact O-N 3.15Å; V89-K92 PolarHBondContact O-N 2.58Å; K92-C96 WeakPolarHBondContact O-CB 3.5Å; K92-C96 PolarHBondContact O-N 2.82Å; K92-C96 VanDerWaalsContact O-N 3.09Å
93	W	79	Confident	73.8	Confident	129 Å²	129	81.1 Å²	81.1	49%	0.489	44%	0.442	S	S	.	.	H	α-helix	trans	-69.9	-35.2	176.6	-76.4	99.1	0	0	0	112.8	V89 V91 G97 P111 V112 L115	V89-W93 PolarHBondContact O-N 2.71Å; V91-W93 VanDerWaalsContact C-N 3.31Å; V91-W93 PolarHBondContact O-N 3.02Å; W93-G97 PolarHBondContact O-N 3.25Å; W93-P111 HydrophobicContact CE3-CB 4.14Å; W93-P111 HydrophobicContact CZ3-CB 4.46Å; W93-V112 HydrophobicContact CB-CG2 4.37Å; W93-V112 WeakPolarHBondContact O-CG2 3.43Å; W93-L115 HydrophobicContact CB-CD1 3.58Å; W93-L115 HydrophobicContact CD2-CD1 4.18Å; W93-L115 HydrophobicContact CG-CD1 3.42Å; W93-L115 VanDerWaalsContact CG-CD1 3.42Å
94	L	77	Confident	72.5	Confident	59 Å²	59	83.6 Å²	83.6	31%	0.309	46%	0.457	S	S	.	.	H	α-helix	trans	-62.5	-46.9	174.1	-178.6	67.8	0	0	0	111.7	N90 V91 G97 C98 V112	N90-L94 WeakPolarHBondContact O-CB 3.32Å; N90-L94 PolarHBondContact O-N 2.81Å; V91-L94 PolarHBondContact O-N 2.82Å; L94-G97 PolarHBondContact O-N 2.86Å; L94-C98 VanDerWaalsContact O-CB 3.27Å; L94-C98 WeakPolarHBondContact O-CB 3.31Å; L94-C98 PolarHBondContact O-N 2.85Å; L94-V112 HydrophobicContact CB-CG1 3.82Å; L94-V112 HydrophobicContact CD1-CG1 3.88Å; L94-V112 HydrophobicContact CG-CG1 4.43Å
95	L	77.9	Confident	71.7	Confident	117 Å²	117	82.8 Å²	82.8	61%	0.613	47%	0.466	S	S	*	.	H	α-helix	trans	-63.3	-43.9	178.6	-69	172.5	0	0	0	111.5	V91 C98 L99	V91-L95 HydrophobicContact CG1-CD1 4.06Å; V91-L95 HydrophobicContact CG1-CG 4.39Å; V91-L95 WeakPolarHBondContact O-CG 3.38Å; V91-L95 PolarHBondContact O-N 2.85Å; L95-C98 PolarHBondContact O-N 2.78Å; L95-L99 WeakPolarHBondContact O-CB 3.27Å; L95-L99 PolarHBondContact O-N 3.32Å
96	C	76.8	Confident	71	Confident	70 Å²	70	76 Å²	76	47%	0.473	44%	0.444	S	S	.	.	H	α-helix	trans	-61.6	-46.8	174.7	-176.3	0	0	0	0	112	K92 C98 L99 C100	K92-C96 WeakPolarHBondContact O-CB 3.5Å; K92-C96 PolarHBondContact O-N 2.82Å; K92-C96 VanDerWaalsContact O-N 3.09Å; C96-C98 VanDerWaalsContact C-N 3.32Å; C96-C98 PolarHBondContact O-N 3.42Å; C96-L99 PolarHBondContact O-N 3.15Å; C96-C100 PolarHBondContact O-N 2.97Å
97	G	74.1	Confident	70.9	Confident	6 Å²	6	82.4 Å²	82.4	6%	0.062	47%	0.47	C	S	.	.	H	α-helix	trans	-65.1	-33.6	179.4	0	0	0	0	0	113.6	W93 L94 C101 S108	W93-G97 PolarHBondContact O-N 3.25Å; L94-G97 PolarHBondContact O-N 2.86Å; G97-C101 WeakPolarHBondContact O-CA 3.37Å; G97-C101 WeakPolarHBondContact O-CB 3.33Å; G97-C101 PolarHBondContact O-N 3.41Å; G97-C101 VanDerWaalsContact O-N 3.09Å; G97-S108 PolarHBondContact O-OG 2.94Å
98	C	73.8	Confident	70.9	Confident	81 Å²	81	83 Å²	83	55%	0.547	48%	0.476	S	S	.	.	H	α-helix	trans	-71.9	-42.2	176.1	-172.7	0	0	0	0	111.9	L94 L95 C96 C100 C101	L94-C98 VanDerWaalsContact O-CB 3.27Å; L94-C98 WeakPolarHBondContact O-CB 3.31Å; L94-C98 PolarHBondContact O-N 2.85Å; L95-C98 PolarHBondContact O-N 2.78Å; C96-C98 VanDerWaalsContact C-N 3.32Å; C96-C98 PolarHBondContact O-N 3.42Å; C98-C100 PolarHBondContact O-N 3.4Å; C98-C101 WeakPolarHBondContact O-CB 3.43Å; C98-C101 PolarHBondContact O-N 2.81Å; C98-C101 VanDerWaalsContact O-N 3.14Å
99	L	74.5	Confident	70.8	Confident	150 Å²	150	81.7 Å²	81.7	79%	0.785	47%	0.465	S	S	*	.	H	α-helix	trans	-61.6	-32.9	176.1	-171.7	63.9	0	0	0	112.3	L95 C96	L95-L99 WeakPolarHBondContact O-CB 3.27Å; L95-L99 PolarHBondContact O-N 3.32Å; C96-L99 PolarHBondContact O-N 3.15Å
100	C	64.7	Low	71	Confident	66 Å²	66	86 Å²	86	45%	0.446	47%	0.473	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.5	2.6	177.9	-62.1	0	0	0	0	114.2	C96 C98 C102 C103	C96-C100 PolarHBondContact O-N 2.97Å; C98-C100 PolarHBondContact O-N 3.4Å; C100-C102 VanDerWaalsContact C-N 3.31Å; C100-C102 PolarHBondContact O-N 3.41Å; C100-C103 PolarHBondContact O-N 2.97Å
101	C	60.9	Low	71.2	Confident	47 Å²	47	88.2 Å²	88.2	32%	0.318	49%	0.488	S	S	.	.	G	3₁₀ helix	trans	-66.6	-27.6	-170.6	179	0	0	0	0	113.6	G97 C98 C103	G97-C101 WeakPolarHBondContact O-CA 3.37Å; G97-C101 WeakPolarHBondContact O-CB 3.33Å; G97-C101 PolarHBondContact O-N 3.41Å; G97-C101 VanDerWaalsContact O-N 3.09Å; C98-C101 WeakPolarHBondContact O-CB 3.43Å; C98-C101 PolarHBondContact O-N 2.81Å; C98-C101 VanDerWaalsContact O-N 3.14Å; C101-C103 PolarHBondContact O-N 3.1Å; C101-C103 VanDerWaalsContact O-N 3.12Å
102	C	60.2	Low	71.2	Confident	123 Å²	123	86 Å²	86	83%	0.831	48%	0.475	S	S	*	.	G	3₁₀ helix	trans	-66	-16.8	-175.6	-48.9	0	0	0	0	113.5	C100	C100-C102 VanDerWaalsContact C-N 3.31Å; C100-C102 PolarHBondContact O-N 3.41Å
103	C	59.7	Low	71.2	Confident	113 Å²	113	81.2 Å²	81.2	76%	0.764	46%	0.456	S	S	*	.	G	3₁₀ helix	trans	-109.7	-7	-167.2	-54.6	0	0	0	0	114.6	C100 C101	C100-C103 PolarHBondContact O-N 2.97Å; C101-C103 PolarHBondContact O-N 3.1Å; C101-C103 VanDerWaalsContact O-N 3.12Å
104	T	61.1	Low	71.3	Confident	55 Å²	55	77.4 Å²	77.4	34%	0.337	45%	0.449	S	S	.	.	T	Hydrogen-bonded Turn	trans	-134.3	16.8	-169.2	61	0	0	0	0	115.4	G106 F107 S108	T104-G106 PolarHBondContact O-N 3.43Å; T104-F107 WeakPolarHBondContact O-CD2 3.01Å; T104-F107 PolarHBondContact O-N 3.39Å; T104-S108 WeakPolarHBondContact OG1-CB 3.43Å; T104-S108 PolarHBondContact OG1-N 3.38Å; T104-S108 PolarHBondContact OG1-OG 2.84Å
105	V	69.3	Low	71.4	Confident	150 Å²	150	76.2 Å²	76.2	91%	0.909	44%	0.442	S	S	*	.	T	Hydrogen-bonded Turn	trans	50.5	31.8	178.7	-159.7	0	0	0	0	112.3
106	G	66.3	Low	71.6	Confident	28 Å²	28	70.8 Å²	70.8	29%	0.289	41%	0.414	S	S	.	.	T	Hydrogen-bonded Turn	trans	92.1	-1.8	177.1	0	0	0	0	0	117.2	T104 S108 L109	T104-G106 PolarHBondContact O-N 3.43Å; G106-S108 PolarHBondContact O-N 3.44Å; G106-L109 WeakPolarHBondContact O-CB 3.36Å; G106-L109 PolarHBondContact O-N 2.96Å; G106-L109 VanDerWaalsContact O-N 3.11Å
107	F	70.2	Confident	72.1	Confident	170 Å²	170	71.1 Å²	71.1	75%	0.746	41%	0.407	S	S	*	.	G	3₁₀ helix	trans	-61.5	-30.5	174.7	-81.2	-77.6	0	0	0	112.9	T104 L109 W110	T104-F107 WeakPolarHBondContact O-CD2 3.01Å; T104-F107 PolarHBondContact O-N 3.39Å; F107-L109 PolarHBondContact O-N 3.45Å; F107-L109 VanDerWaalsContact O-N 3.09Å; F107-W110 WeakPolarHBondContact O-CB 3.31Å; F107-W110 PolarHBondContact O-N 2.93Å; F107-W110 VanDerWaalsContact O-N 3.13Å
108	S	69.9	Low	72.7	Confident	27 Å²	27	79.2 Å²	79.2	19%	0.189	44%	0.436	C	S	.	.	G	3₁₀ helix	trans	-61.4	-15	175.3	64.5	0	0	0	0	114.4	G97 T104 G106 P111	G97-S108 PolarHBondContact O-OG 2.94Å; T104-S108 WeakPolarHBondContact OG1-CB 3.43Å; T104-S108 PolarHBondContact OG1-N 3.38Å; T104-S108 PolarHBondContact OG1-OG 2.84Å; G106-S108 PolarHBondContact O-N 3.44Å; S108-P111 WeakPolarHBondContact O-CD 3.22Å
109	L	68.7	Low	73.4	Confident	47 Å²	47	75.4 Å²	75.4	25%	0.246	41%	0.411	C	S	.	.	G	3₁₀ helix	trans	-89.4	-13	178.9	-60.8	175.5	0	0	0	113.2	G106 F107 P111 V112 I113	G106-L109 WeakPolarHBondContact O-CB 3.36Å; G106-L109 PolarHBondContact O-N 2.96Å; G106-L109 VanDerWaalsContact O-N 3.11Å; F107-L109 PolarHBondContact O-N 3.45Å; F107-L109 VanDerWaalsContact O-N 3.09Å; L109-P111 VanDerWaalsContact C-CD 3.46Å; L109-V112 WeakPolarHBondContact O-CB 3.48Å; L109-V112 PolarHBondContact O-N 3.28Å; L109-I113 WeakPolarHBondContact O-CG1 3.43Å; L109-I113 PolarHBondContact O-N 3.4Å
110	W	78.8	Confident	74.2	Confident	158 Å²	158	71 Å²	71	60%	0.598	38%	0.384	S	S	*	.	H	α-helix	trans	-54.6	-42.2	178.8	-175	-100.3	0	0	0	114.1	F107 V112 I113 C114	F107-W110 WeakPolarHBondContact O-CB 3.31Å; F107-W110 PolarHBondContact O-N 2.93Å; F107-W110 VanDerWaalsContact O-N 3.13Å; W110-V112 VanDerWaalsContact C-N 3.29Å; W110-V112 PolarHBondContact O-N 3.05Å; W110-I113 PolarHBondContact O-N 2.97Å; W110-C114 PolarHBondContact NE1-SG 3.44Å; W110-C114 VanDerWaalsContact NE1-SG 3.38Å; W110-C114 WeakPolarHBondContact O-CB 3.28Å; W110-C114 PolarHBondContact O-N 3.44Å; W110-C114 PolarHBondContact O-SG 3.48Å
111	P	76.8	Confident	75.6	Confident	52 Å²	52	75.4 Å²	75.4	34%	0.338	39%	0.391	S	S	.	.	H	α-helix	trans	-58.2	-40.3	174.2	-25.2	36.2	0	0	0	112.6	W93 S108 L109 C114 L115	W93-P111 HydrophobicContact CE3-CB 4.14Å; W93-P111 HydrophobicContact CZ3-CB 4.46Å; S108-P111 WeakPolarHBondContact O-CD 3.22Å; L109-P111 VanDerWaalsContact C-CD 3.46Å; P111-C114 PolarHBondContact O-N 3.13Å; P111-L115 WeakPolarHBondContact O-CB 3.37Å; P111-L115 VanDerWaalsContact O-CG 3.27Å; P111-L115 WeakPolarHBondContact O-CG 3.44Å; P111-L115 PolarHBondContact O-N 2.7Å
112	V	76.8	Confident	77.1	Confident	1 Å²	1	75.5 Å²	75.5	1%	0.006	39%	0.392	C	S	.	.	H	α-helix	trans	-69.8	-40.1	-179.2	-160.5	0	0	0	0	111.1	F49 W93 L94 L109 W110 C114 L115 N116	F49-V112 HydrophobicContact CE2-CB 4.28Å; F49-V112 HydrophobicContact CE2-CG1 3.8Å; F49-V112 HydrophobicContact CZ-CG1 4.49Å; W93-V112 HydrophobicContact CB-CG2 4.37Å; W93-V112 WeakPolarHBondContact O-CG2 3.43Å; L94-V112 HydrophobicContact CB-CG1 3.82Å; L94-V112 HydrophobicContact CD1-CG1 3.88Å; L94-V112 HydrophobicContact CG-CG1 4.43Å; L109-V112 WeakPolarHBondContact O-CB 3.48Å; L109-V112 PolarHBondContact O-N 3.28Å; W110-V112 VanDerWaalsContact C-N 3.29Å; W110-V112 PolarHBondContact O-N 3.05Å; V112-C114 VanDerWaalsContact C-N 3.34Å; V112-L115 PolarHBondContact O-N 2.94Å; V112-N116 WeakPolarHBondContact O-CB 3.33Å; V112-N116 PolarHBondContact O-N 2.96Å
113	I	79.7	Confident	78.7	Confident	57 Å²	57	69.7 Å²	69.7	29%	0.292	35%	0.353	S	S	.	.	H	α-helix	trans	-62.4	-43.7	174.2	-64.1	168	0	0	0	110.3	F49 L109 W110 N116 K117	F49-I113 HydrophobicContact CE2-CG1 4.48Å; F49-I113 HydrophobicContact CZ-CG1 4.13Å; L109-I113 WeakPolarHBondContact O-CG1 3.43Å; L109-I113 PolarHBondContact O-N 3.4Å; W110-I113 PolarHBondContact O-N 2.97Å; I113-N116 PolarHBondContact O-N 3.24Å; I113-K117 WeakPolarHBondContact O-CG 3.48Å; I113-K117 PolarHBondContact O-N 3.36Å
114	C	80.5	Confident	80.5	Confident	49 Å²	49	68.9 Å²	68.9	33%	0.331	34%	0.338	S	S	.	.	H	α-helix	trans	-63.7	-42.5	177.4	-72.9	0	0	0	0	112.3	W110 P111 V112 K117 R118	W110-C114 PolarHBondContact NE1-SG 3.44Å; W110-C114 VanDerWaalsContact NE1-SG 3.38Å; W110-C114 WeakPolarHBondContact O-CB 3.28Å; W110-C114 PolarHBondContact O-N 3.44Å; W110-C114 PolarHBondContact O-SG 3.48Å; P111-C114 PolarHBondContact O-N 3.13Å; V112-C114 VanDerWaalsContact C-N 3.34Å; C114-K117 WeakPolarHBondContact O-CB 3.28Å; C114-K117 PolarHBondContact O-N 2.87Å; C114-R118 PolarHBondContact O-N 2.99Å
115	L	78.3	Confident	82.2	Confident	33 Å²	33	73.4 Å²	73.4	17%	0.173	35%	0.353	C	S	.	.	H	α-helix	trans	-63.1	-41.2	175.6	-77.6	172.8	0	0	0	112.2	V89 N90 W93 P111 V112 R118 A119	V89-L115 HydrophobicContact CG1-CD1 4.41Å; V89-L115 HydrophobicContact CG1-CD2 4.33Å; N90-L115 WeakPolarHBondContact OD1-CB 3.43Å; W93-L115 HydrophobicContact CB-CD1 3.58Å; W93-L115 HydrophobicContact CD2-CD1 4.18Å; W93-L115 HydrophobicContact CG-CD1 3.42Å; W93-L115 VanDerWaalsContact CG-CD1 3.42Å; P111-L115 WeakPolarHBondContact O-CB 3.37Å; P111-L115 VanDerWaalsContact O-CG 3.27Å; P111-L115 WeakPolarHBondContact O-CG 3.44Å; P111-L115 PolarHBondContact O-N 2.7Å; V112-L115 PolarHBondContact O-N 2.94Å; L115-R118 WeakPolarHBondContact O-CB 3.41Å; L115-R118 PolarHBondContact O-N 2.93Å; L115-A119 PolarHBondContact O-N 2.9Å
116	N	83.1	Confident	83.5	Confident	3 Å²	3	68 Å²	68	2%	0.016	32%	0.318	C	S	.	.	H	α-helix	trans	-64.8	-42.8	173.8	-170	-72.9	0	0	0	111.8	V48 F49 V112 I113 R118 A119 R120	V48-N116 PolarHBondContact O-ND2 3.44Å; F49-N116 HydrophobicContact CD2-CB 3.94Å; V112-N116 WeakPolarHBondContact O-CB 3.33Å; V112-N116 PolarHBondContact O-N 2.96Å; I113-N116 PolarHBondContact O-N 3.24Å; N116-R118 VanDerWaalsContact C-N 3.28Å; N116-R118 PolarHBondContact O-N 3.25Å; N116-A119 PolarHBondContact O-N 3.44Å; N116-R120 WeakPolarHBondContact O-CG 3.39Å; N116-R120 PolarHBondContact O-N 3.11Å; N116-R120 PolarHBondContact OD1-NE 3.23Å
117	K	87.1	Confident	85	Confident	77 Å²	77	66.8 Å²	66.8	34%	0.335	31%	0.305	S	S	.	.	H	α-helix	trans	-56.3	-42	171.3	-78.2	177.1	-179.7	178.2	0	111.4	I113 C114 R120 R121	I113-K117 WeakPolarHBondContact O-CG 3.48Å; I113-K117 PolarHBondContact O-N 3.36Å; C114-K117 WeakPolarHBondContact O-CB 3.28Å; C114-K117 PolarHBondContact O-N 2.87Å; K117-R120 PolarHBondContact O-N 3.28Å; K117-R121 WeakPolarHBondContact O-CG 3.46Å; K117-R121 PolarHBondContact O-N 2.8Å
118	R	87.6	Confident	86.3	Confident	176 Å²	176	64.3 Å²	64.3	66%	0.664	30%	0.296	S	S	*	.	H	α-helix	trans	-62.7	-47.8	177.3	-177	178.5	-175.8	145.7	1.9	111.9	C114 L115 N116 R120 R121 S122	C114-R118 PolarHBondContact O-N 2.99Å; L115-R118 WeakPolarHBondContact O-CB 3.41Å; L115-R118 PolarHBondContact O-N 2.93Å; N116-R118 VanDerWaalsContact C-N 3.28Å; N116-R118 PolarHBondContact O-N 3.25Å; R118-R120 VanDerWaalsContact C-N 3.34Å; R118-R120 PolarHBondContact O-N 3.09Å; R118-R121 PolarHBondContact O-N 3.3Å; R118-S122 PolarHBondContact O-N 3.34Å
119	A	87.8	Confident	87.6	Confident	2 Å²	2	69.2 Å²	69.2	2%	0.017	31%	0.311	C	S	.	.	H	α-helix	trans	-59	-46	177.5	0	0	0	0	0	111.3	L51 N86 L115 N116 R121 S122 I123	L51-A119 HydrophobicContact CD2-CB 4.24Å; N86-A119 HydrophobicContact CB-CB 4.09Å; L115-A119 PolarHBondContact O-N 2.9Å; N116-A119 PolarHBondContact O-N 3.44Å; A119-R121 PolarHBondContact O-N 3.4Å; A119-S122 WeakPolarHBondContact O-CB 3.25Å; A119-S122 PolarHBondContact O-N 3.11Å; A119-I123 WeakPolarHBondContact O-CG1 3.3Å; A119-I123 PolarHBondContact O-N 2.86Å
120	R	91.8	Very high	89	Confident	57 Å²	57	67 Å²	67	22%	0.215	30%	0.299	C	S	.	.	H	α-helix	trans	-58.5	-48.1	176.5	-72.6	-175.9	-74	145.9	-13.9	112.8	L51 N116 K117 R118 S122 I123 Q124 L144 Y157	L51-R120 HydrophobicContact CD2-CG 4.15Å; N116-R120 WeakPolarHBondContact O-CG 3.39Å; N116-R120 PolarHBondContact O-N 3.11Å; N116-R120 PolarHBondContact OD1-NE 3.23Å; K117-R120 PolarHBondContact O-N 3.28Å; R118-R120 VanDerWaalsContact C-N 3.34Å; R118-R120 PolarHBondContact O-N 3.09Å; R120-S122 VanDerWaalsContact C-N 3.28Å; R120-S122 PolarHBondContact O-N 3.12Å; R120-I123 PolarHBondContact O-N 3.35Å; R120-Q124 WeakPolarHBondContact O-CG 3.41Å; R120-Q124 PolarHBondContact O-N 3.3Å; R120-L144 HydrophobicContact CB-CD2 4.38Å; R120-L144 HydrophobicContact CG-CD2 4.31Å; R120-Y157 PolarHBondContact NH1-OH 3.12Å
121	R	92.4	Very high	90	Very high	158 Å²	158	59.7 Å²	59.7	60%	0.596	27%	0.272	S	S	*	.	H	α-helix	trans	-60.2	-39	176.5	-71.5	175.3	-169.7	166.4	0.6	112	K117 R118 A119 I123 Q124 K125	K117-R121 WeakPolarHBondContact O-CG 3.46Å; K117-R121 PolarHBondContact O-N 2.8Å; R118-R121 PolarHBondContact O-N 3.3Å; A119-R121 PolarHBondContact O-N 3.4Å; R121-I123 VanDerWaalsContact C-N 3.35Å; R121-Q124 PolarHBondContact O-N 3.41Å; R121-K125 WeakPolarHBondContact O-CG 3.28Å; R121-K125 PolarHBondContact O-N 3.04Å
122	S	92.8	Very high	91	Very high	49 Å²	49	61.8 Å²	61.8	34%	0.343	28%	0.28	S	S	.	.	H	α-helix	trans	-63.5	-41.4	177.5	-167.2	0	0	0	0	111.9	C82 R118 A119 R120 L126	C82-S122 PolarHBondContact SG-OG 2.93Å; R118-S122 PolarHBondContact O-N 3.34Å; A119-S122 WeakPolarHBondContact O-CB 3.25Å; A119-S122 PolarHBondContact O-N 3.11Å; R120-S122 VanDerWaalsContact C-N 3.28Å; R120-S122 PolarHBondContact O-N 3.12Å; S122-L126 WeakPolarHBondContact O-CB 3.47Å; S122-L126 PolarHBondContact O-N 3.28Å; S122-L126 VanDerWaalsContact O-N 3.11Å
123	I	94.8	Very high	92	Very high	1 Å²	1	65.4 Å²	65.4	1%	0.005	29%	0.294	C	S	.	.	H	α-helix	trans	-67.8	-46.4	176.5	-63.6	162.8	0	0	0	110.2	L51 V79 L83 A119 R120 R121 K125 L126 L127 L144	L51-I123 HydrophobicContact CD1-CD1 4.12Å; L51-I123 HydrophobicContact CD2-CD1 4.06Å; V79-I123 HydrophobicContact CG1-CG2 4.21Å; L83-I123 HydrophobicContact CD2-CD1 3.41Å; L83-I123 VanDerWaalsContact CD2-CD1 3.41Å; L83-I123 HydrophobicContact CD2-CG1 4.46Å; L83-I123 HydrophobicContact CG-CD1 3.93Å; A119-I123 WeakPolarHBondContact O-CG1 3.3Å; A119-I123 PolarHBondContact O-N 2.86Å; R120-I123 PolarHBondContact O-N 3.35Å; R121-I123 VanDerWaalsContact C-N 3.35Å; I123-K125 VanDerWaalsContact C-N 3.32Å; I123-K125 PolarHBondContact O-N 2.95Å; I123-L126 WeakPolarHBondContact O-CB 3.21Å; I123-L126 PolarHBondContact O-N 2.92Å; I123-L127 HydrophobicContact CG2-CD1 4.13Å; I123-L127 HydrophobicContact CG2-CG 4.19Å; I123-L127 WeakPolarHBondContact O-CG 3.41Å; I123-L127 PolarHBondContact O-N 2.9Å; I123-L144 HydrophobicContact CB-CD2 4.36Å; I123-L144 HydrophobicContact CG2-CD1 4.37Å; I123-L144 HydrophobicContact CG2-CD2 4.18Å
124	Q	96.3	Very high	92.8	Very high	96 Å²	96	64.3 Å²	64.3	45%	0.449	29%	0.288	S	S	.	.	H	α-helix	trans	-55.8	-46.9	178.1	-74.7	173.9	-38.7	0	0	111.8	R120 R121 L126 L127 E128 L144	R120-Q124 WeakPolarHBondContact O-CG 3.41Å; R120-Q124 PolarHBondContact O-N 3.3Å; R121-Q124 PolarHBondContact O-N 3.41Å; Q124-L126 VanDerWaalsContact C-N 3.32Å; Q124-L126 PolarHBondContact O-N 3.37Å; Q124-L127 PolarHBondContact O-N 3.35Å; Q124-E128 WeakPolarHBondContact O-CB 3.49Å; Q124-E128 PolarHBondContact O-N 3.06Å; Q124-L144 HydrophobicContact CG-CB 4.16Å; Q124-L144 HydrophobicContact CG-CD2 4.33Å
125	K	97	Very high	93.6	Very high	151 Å²	151	62 Å²	62	66%	0.657	27%	0.273	S	S	*	.	H	α-helix	trans	-61.5	-38.6	175.3	-73.5	-176.4	176.5	-165.8	0	113	R121 I123 W129	R121-K125 WeakPolarHBondContact O-CG 3.28Å; R121-K125 PolarHBondContact O-N 3.04Å; I123-K125 VanDerWaalsContact C-N 3.32Å; I123-K125 PolarHBondContact O-N 2.95Å; K125-W129 WeakPolarHBondContact O-CB 3.37Å; K125-W129 PolarHBondContact O-N 2.99Å
126	L	97.1	Very high	94.4	Very high	35 Å²	35	63.9 Å²	63.9	18%	0.183	28%	0.28	C	S	.	.	H	α-helix	trans	-66.5	-43.1	177	177.4	64.3	0	0	0	111.5	R78 V79 C82 S122 I123 Q124 E128 W129 E130	R78-L126 HydrophobicContact CB-CD1 4.46Å; R78-L126 HydrophobicContact CB-CD2 4.14Å; V79-L126 HydrophobicContact CB-CD2 4.36Å; V79-L126 HydrophobicContact CG2-CD2 3.84Å; V79-L126 HydrophobicContact CG2-CG 4.49Å; C82-L126 HydrophobicContact CB-CD2 4.27Å; S122-L126 WeakPolarHBondContact O-CB 3.47Å; S122-L126 PolarHBondContact O-N 3.28Å; S122-L126 VanDerWaalsContact O-N 3.11Å; I123-L126 WeakPolarHBondContact O-CB 3.21Å; I123-L126 PolarHBondContact O-N 2.92Å; Q124-L126 VanDerWaalsContact C-N 3.32Å; Q124-L126 PolarHBondContact O-N 3.37Å; L126-E128 VanDerWaalsContact C-N 3.34Å; L126-W129 HydrophobicContact CD1-CE3 4.4Å; L126-W129 PolarHBondContact O-N 3.35Å; L126-E130 PolarHBondContact O-N 3.41Å
127	L	97.8	Very high	94.9	Very high	3 Å²	3	71.6 Å²	71.6	2%	0.016	31%	0.314	C	S	.	.	H	α-helix	trans	-62.9	-42.4	176.1	-66.9	-178.3	0	0	0	111.2	V79 I123 Q124 W129 E130 N131 W142 L144	V79-L127 HydrophobicContact CG2-CD2 3.87Å; I123-L127 HydrophobicContact CG2-CD1 4.13Å; I123-L127 HydrophobicContact CG2-CG 4.19Å; I123-L127 WeakPolarHBondContact O-CG 3.41Å; I123-L127 PolarHBondContact O-N 2.9Å; Q124-L127 PolarHBondContact O-N 3.35Å; L127-W129 VanDerWaalsContact C-N 3.32Å; L127-W129 PolarHBondContact O-N 2.95Å; L127-E130 PolarHBondContact O-N 2.96Å; L127-N131 VanDerWaalsContact O-CB 3.28Å; L127-N131 WeakPolarHBondContact O-CB 3.44Å; L127-N131 PolarHBondContact O-N 2.93Å; L127-N131 PolarHBondContact O-ND2 3.46Å; L127-W142 HydrophobicContact CD2-CB 4.14Å; L127-W142 HydrophobicContact CD2-CE3 3.77Å; L127-L144 HydrophobicContact CD1-CB 3.97Å
128	E	97.9	Very high	95.3	Very high	118 Å²	118	70.3 Å²	70.3	55%	0.551	31%	0.31	S	S	*	.	H	α-helix	trans	-61.6	-40.3	175.8	-168.6	168.2	-157.3	0	0	112	Q124 L126 N131 N132	Q124-E128 WeakPolarHBondContact O-CB 3.49Å; Q124-E128 PolarHBondContact O-N 3.06Å; L126-E128 VanDerWaalsContact C-N 3.34Å; E128-N131 WeakPolarHBondContact O-CB 3.47Å; E128-N131 PolarHBondContact O-N 2.97Å; E128-N132 VanDerWaalsContact O-CG 3.25Å; E128-N132 PolarHBondContact O-N 3.29Å; E128-N132 PolarHBondContact O-ND2 2.94Å
129	W	97.8	Very high	95.6	Very high	131 Å²	131	62.6 Å²	62.6	50%	0.496	29%	0.285	S	S	.	.	H	α-helix	trans	-64.9	-45.3	173.3	179.9	87.2	0	0	0	112.8	K125 L126 L127 N131 N132 R133	K125-W129 WeakPolarHBondContact O-CB 3.37Å; K125-W129 PolarHBondContact O-N 2.99Å; L126-W129 HydrophobicContact CD1-CE3 4.4Å; L126-W129 PolarHBondContact O-N 3.35Å; L127-W129 VanDerWaalsContact C-N 3.32Å; L127-W129 PolarHBondContact O-N 2.95Å; W129-N131 VanDerWaalsContact C-N 3.3Å; W129-N131 PolarHBondContact O-N 3.48Å; W129-N132 PolarHBondContact O-N 2.95Å; W129-R133 VanDerWaalsContact O-CB 3.25Å; W129-R133 WeakPolarHBondContact O-CB 3.4Å; W129-R133 PolarHBondContact O-N 3.2Å
130	E	98	Very high	96	Very high	1 Å²	1	62.5 Å²	62.5	1%	0.005	29%	0.285	C	S	.	.	H	α-helix	trans	-62.1	-38.9	175.4	-75.6	-70.4	173.7	0	0	111.9	S75 R78 L126 L127 R133 L134 Y135	S75-E130 VanDerWaalsContact OG-CD 3.24Å; S75-E130 PolarHBondContact OG-OE2 3.01Å; R78-E130 VanDerWaalsContact CD-OE1 3.28Å; R78-E130 WeakPolarHBondContact CD-OE1 3.48Å; R78-E130 IonicContact CZ-OE1 3.68Å; R78-E130 IonicContact NE-OE1 3.9Å; R78-E130 IonicContact NH1-OE1 2.7Å; R78-E130 PolarHBondContact NH1-OE1 3.07Å; R78-E130 IonicContact NH1-OE2 3.74Å; L126-E130 PolarHBondContact O-N 3.41Å; L127-E130 PolarHBondContact O-N 2.96Å; E130-R133 PolarHBondContact O-N 3.4Å; E130-R133 IonicContact OE1-NH2 2.62Å; E130-R133 IonicContact OE2-CZ 3.55Å; E130-R133 IonicContact OE2-NE 3.13Å; E130-R133 PolarHBondContact OE2-NE 3.28Å; E130-R133 VanDerWaalsContact OE2-NE 3.13Å; E130-R133 IonicContact OE2-NH2 3.99Å; E130-R133 PolarHBondContact OE2-NH2 3.37Å; E130-L134 PolarHBondContact O-N 2.91Å; E130-Y135 HydrophobicContact CB-CD2 4.11Å; E130-Y135 HydrophobicContact CB-CE2 4.1Å; E130-Y135 PolarHBondContact O-N 3.02Å
131	N	98.1	Very high	96.2	Very high	3 Å²	3	62.4 Å²	62.4	2%	0.016	29%	0.287	C	S	.	.	H	α-helix	trans	-59.4	-52.6	176.6	-81.5	-20.7	0	0	0	112.1	L127 E128 W129 R133 L134 Y135 H136 W142	L127-N131 VanDerWaalsContact O-CB 3.28Å; L127-N131 WeakPolarHBondContact O-CB 3.44Å; L127-N131 PolarHBondContact O-N 2.93Å; L127-N131 PolarHBondContact O-ND2 3.46Å; E128-N131 WeakPolarHBondContact O-CB 3.47Å; E128-N131 PolarHBondContact O-N 2.97Å; W129-N131 VanDerWaalsContact C-N 3.3Å; W129-N131 PolarHBondContact O-N 3.48Å; N131-R133 VanDerWaalsContact C-N 3.31Å; N131-R133 PolarHBondContact O-N 3Å; N131-L134 PolarHBondContact O-N 3.45Å; N131-Y135 PolarHBondContact O-N 3.47Å; N131-H136 WeakPolarHBondContact O-CB 3.39Å; N131-H136 PolarHBondContact O-N 3.37Å; N131-W142 PolarHBondContact ND2-N 3.43Å; N131-W142 PolarHBondContact ND2-O 3.09Å; N131-W142 WeakPolarHBondContact OD1-CB 3.42Å; N131-W142 PolarHBondContact OD1-N 3.01Å
132	N	98	Very high	96.5	Very high	97 Å²	97	55 Å²	55	52%	0.519	26%	0.259	S	S	.	.	H	α-helix	trans	-67	-34	179.5	-65.5	-17.4	0	0	0	111.9	E128 W129 H136	E128-N132 VanDerWaalsContact O-CG 3.25Å; E128-N132 PolarHBondContact O-N 3.29Å; E128-N132 PolarHBondContact O-ND2 2.94Å; W129-N132 PolarHBondContact O-N 2.95Å; N132-H136 PolarHBondContact OD1-CE1 3.22Å; N132-H136 PolarHBondContact OD1-ND1 3.21Å
133	R	97.3	Very high	96.7	Very high	77 Å²	77	56 Å²	56	29%	0.291	26%	0.257	S	S	.	.	H	α-helix	trans	-65.3	-49.2	177.8	-177.4	179.3	82	101.9	2.5	111.8	E71 W129 E130 N131 K137	E71-R133 IonicContact OE2-CZ 3.8Å; E71-R133 IonicContact OE2-NH1 3.02Å; E71-R133 PolarHBondContact OE2-NH1 3.07Å; E71-R133 IonicContact OE2-NH2 2.63Å; E71-R133 PolarHBondContact OE2-NH2 3.27Å; W129-R133 VanDerWaalsContact O-CB 3.25Å; W129-R133 WeakPolarHBondContact O-CB 3.4Å; W129-R133 PolarHBondContact O-N 3.2Å; E130-R133 PolarHBondContact O-N 3.4Å; E130-R133 IonicContact OE1-NH2 2.62Å; E130-R133 IonicContact OE2-CZ 3.55Å; E130-R133 IonicContact OE2-NE 3.13Å; E130-R133 PolarHBondContact OE2-NE 3.28Å; E130-R133 VanDerWaalsContact OE2-NE 3.13Å; E130-R133 IonicContact OE2-NH2 3.99Å; E130-R133 PolarHBondContact OE2-NH2 3.37Å; N131-R133 VanDerWaalsContact C-N 3.31Å; N131-R133 PolarHBondContact O-N 3Å; R133-K137 WeakPolarHBondContact O-CE 3.27Å; R133-K137 PolarHBondContact O-NZ 3.16Å
134	L	96.8	Very high	96.7	Very high	34 Å²	34	56.8 Å²	56.8	18%	0.178	26%	0.261	C	S	.	.	T	Hydrogen-bonded Turn	trans	-137.1	-58.8	-165.3	178.8	63.2	0	0	0	113.4	V67 E71 E130 N131 H136 K137 L138	V67-L134 HydrophobicContact CG2-CD2 4.38Å; E71-L134 HydrophobicContact CB-CD2 3.81Å; E71-L134 HydrophobicContact CG-CD2 4.02Å; E130-L134 PolarHBondContact O-N 2.91Å; N131-L134 PolarHBondContact O-N 3.45Å; L134-H136 PolarHBondContact O-N 3.2Å; L134-K137 WeakPolarHBondContact O-CB 3.5Å; L134-K137 PolarHBondContact O-N 3.15Å; L134-L138 HydrophobicContact CD1-CD1 3.86Å; L134-L138 HydrophobicContact CD1-CG 4.17Å; L134-L138 HydrophobicContact CD2-CD1 4.33Å; L134-L138 HydrophobicContact CG-CD1 3.8Å; L134-L138 HydrophobicContact CG-CG 4.4Å; L134-L138 PolarHBondContact O-N 2.99Å
135	Y	97.1	Very high	96.7	Very high	0 Å²	0	53.7 Å²	53.7	0%	0	25%	0.25	C	S	.	.	G	3₁₀ helix	trans	-66.4	-34	-161.3	-68.4	-79.9	0	0	0	114	V67 S75 E130 N131 K137 L138 G139 L140 W142	V67-Y135 HydrophobicContact CB-CE1 4.5Å; V67-Y135 HydrophobicContact CG2-CE1 3.92Å; S75-Y135 WeakPolarHBondContact CB-OH 3.33Å; S75-Y135 WeakPolarHBondContact OG-CE2 3.37Å; S75-Y135 PolarHBondContact OG-OH 3.33Å; E130-Y135 HydrophobicContact CB-CD2 4.11Å; E130-Y135 HydrophobicContact CB-CE2 4.1Å; E130-Y135 PolarHBondContact O-N 3.02Å; N131-Y135 PolarHBondContact O-N 3.47Å; Y135-K137 VanDerWaalsContact C-N 3.26Å; Y135-K137 PolarHBondContact O-N 3.24Å; Y135-L138 HydrophobicContact CD1-CD1 4.47Å; Y135-L138 CarbonylContact O-C 3.54Å; Y135-L138 WeakPolarHBondContact O-CA 3.4Å; Y135-L138 WeakPolarHBondContact O-CB 3.34Å; Y135-L138 PolarHBondContact O-N 3.18Å; Y135-G139 PolarHBondContact O-N 3.31Å; Y135-G139 VanDerWaalsContact O-N 3.17Å; Y135-L140 CarbonylContact C-O 3.6Å; Y135-L140 WeakPolarHBondContact CB-O 3.3Å; Y135-L140 HydrophobicContact CD1-CB 4.05Å; Y135-L140 HydrophobicContact CD1-CD1 3.94Å; Y135-L140 PolarHBondContact O-N 3.37Å; Y135-W142 AromaticContact CD1-CD1 3.69Å; Y135-W142 AromaticContact CD1-NE1 3.18Å; Y135-W142 AromaticContact CD2-CD1 3.84Å; Y135-W142 HydrophobicContact CD2-CG 4.4Å; Y135-W142 AromaticContact CD2-NE1 3.8Å; Y135-W142 AromaticContact CE1-CE2 3.63Å; Y135-W142 AromaticContact CE1-CZ2 3.8Å; Y135-W142 HydrophobicContact CE1-CZ2 3.8Å; Y135-W142 AromaticContact CE1-NE1 3.09Å; Y135-W142 HydrophobicContact CE2-CD2 4.39Å; Y135-W142 AromaticContact CE2-CE2 3.87Å; Y135-W142 HydrophobicContact CE2-CZ2 4.18Å; Y135-W142 AromaticContact CE2-NE1 3.75Å; Y135-W142 AromaticContact CG-CD1 3.6Å; Y135-W142 AromaticContact CG-NE1 3.55Å; Y135-W142 AromaticContact CZ-CE2 3.5Å; Y135-W142 VanDerWaalsContact CZ-CE2 3.5Å; Y135-W142 AromaticContact CZ-CZ2 3.5Å; Y135-W142 VanDerWaalsContact CZ-CZ2 3.5Å; Y135-W142 AromaticContact CZ-NE1 3.41Å; Y135-W142 VanDerWaalsContact OH-CZ2 3.3Å; Y135-W142 WeakPolarHBondContact OH-CZ2 3.35Å
136	H	96.2	Very high	96.5	Very high	73 Å²	73	51.9 Å²	51.9	34%	0.338	24%	0.242	S	C	.	.	G	3₁₀ helix	trans	-62.1	-35.9	175	-71.6	173.2	0	0	0	112.2	N131 N132 L134 L138 G139 L140 H141	N131-H136 WeakPolarHBondContact O-CB 3.39Å; N131-H136 PolarHBondContact O-N 3.37Å; N132-H136 PolarHBondContact OD1-CE1 3.22Å; N132-H136 PolarHBondContact OD1-ND1 3.21Å; L134-H136 PolarHBondContact O-N 3.2Å; H136-L138 PolarHBondContact O-N 3Å; H136-G139 PolarHBondContact O-N 3.2Å; H136-L140 PolarHBondContact CD2-O 3.14Å; H136-L140 PolarHBondContact N-O 3.01Å; H136-H141 AromaticContact CD2-ND1 3.96Å; H136-H141 AromaticContact NE2-CE1 3.92Å; H136-H141 AromaticContact NE2-ND1 3.15Å; H136-H141 PolarHBondContact NE2-ND1 3.4Å; H136-H141 VanDerWaalsContact NE2-ND1 3.15Å
137	K	94.3	Very high	96.3	Very high	164 Å²	164	54 Å²	54	71%	0.713	25%	0.248	S	C	*	.	G	3₁₀ helix	trans	-65.9	-24.7	175.2	-56.3	172.8	-177.4	164	0	112	R133 L134 Y135	R133-K137 WeakPolarHBondContact O-CE 3.27Å; R133-K137 PolarHBondContact O-NZ 3.16Å; L134-K137 WeakPolarHBondContact O-CB 3.5Å; L134-K137 PolarHBondContact O-N 3.15Å; Y135-K137 VanDerWaalsContact C-N 3.26Å; Y135-K137 PolarHBondContact O-N 3.24Å
138	L	94.4	Very high	96	Very high	50 Å²	50	59.5 Å²	59.5	26%	0.262	27%	0.271	S	S	.	.	G	3₁₀ helix	trans	-90.1	-1.8	176.3	-56	177.8	0	0	0	112.8	V67 L134 Y135 H136 L140	V67-L138 HydrophobicContact CB-CD1 3.89Å; V67-L138 HydrophobicContact CG2-CD1 3.72Å; L134-L138 HydrophobicContact CD1-CD1 3.86Å; L134-L138 HydrophobicContact CD1-CG 4.17Å; L134-L138 HydrophobicContact CD2-CD1 4.33Å; L134-L138 HydrophobicContact CG-CD1 3.8Å; L134-L138 HydrophobicContact CG-CG 4.4Å; L134-L138 PolarHBondContact O-N 2.99Å; Y135-L138 HydrophobicContact CD1-CD1 4.47Å; Y135-L138 CarbonylContact O-C 3.54Å; Y135-L138 WeakPolarHBondContact O-CA 3.4Å; Y135-L138 WeakPolarHBondContact O-CB 3.34Å; Y135-L138 PolarHBondContact O-N 3.18Å; H136-L138 PolarHBondContact O-N 3Å; L138-L140 HydrophobicContact CB-CD1 4.2Å; L138-L140 HydrophobicContact CB-CG 4.31Å
139	G	93.9	Very high	95.4	Very high	14 Å²	14	54.8 Å²	54.8	14%	0.144	25%	0.251	C	S	.	.	T	Hydrogen-bonded Turn	trans	70.1	34	-172.8	0	0	0	0	0	112.9	Y135 H136 L164	Y135-G139 PolarHBondContact O-N 3.31Å; Y135-G139 VanDerWaalsContact O-N 3.17Å; H136-G139 PolarHBondContact O-N 3.2Å; G139-L164 PolarHBondContact O-N 3.09Å
140	L	95.8	Very high	94.6	Very high	1 Å²	1	56.1 Å²	56.1	1%	0.005	26%	0.263	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.2	149.1	179.4	-63	174	0	0	0	110.2	L63 K66 Y135 H136 L138 I161 E162 F163	L63-L140 HydrophobicContact CD2-CD1 4.27Å; L63-L140 HydrophobicContact CD2-CD2 4.22Å; K66-L140 HydrophobicContact CB-CD1 4.36Å; Y135-L140 CarbonylContact C-O 3.6Å; Y135-L140 WeakPolarHBondContact CB-O 3.3Å; Y135-L140 HydrophobicContact CD1-CB 4.05Å; Y135-L140 HydrophobicContact CD1-CD1 3.94Å; Y135-L140 PolarHBondContact O-N 3.37Å; H136-L140 PolarHBondContact CD2-O 3.14Å; H136-L140 PolarHBondContact N-O 3.01Å; L138-L140 HydrophobicContact CB-CD1 4.2Å; L138-L140 HydrophobicContact CB-CG 4.31Å; L140-I161 HydrophobicContact CB-CG2 4.26Å; L140-I161 HydrophobicContact CD2-CG2 4.12Å; L140-E162 CarbonylContact C-O 3.5Å; L140-E162 VanDerWaalsContact CA-O 3.3Å; L140-E162 WeakPolarHBondContact CA-O 3.4Å; L140-F163 HydrophobicContact CD2-CD1 3.52Å; L140-F163 HydrophobicContact CD2-CE1 3.63Å; L140-F163 HydrophobicContact CD2-CG 4.26Å; L140-F163 HydrophobicContact CD2-CZ 4.44Å
141	H	96.8	Very high	93.7	Very high	55 Å²	55	61.5 Å²	61.5	26%	0.255	30%	0.301	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-136.4	115.2	177.1	-176.7	100	0	0	0	111.1	H136 I161 E162 L164	H136-H141 AromaticContact CD2-ND1 3.96Å; H136-H141 AromaticContact NE2-CE1 3.92Å; H136-H141 AromaticContact NE2-ND1 3.15Å; H136-H141 PolarHBondContact NE2-ND1 3.4Å; H136-H141 VanDerWaalsContact NE2-ND1 3.15Å; H141-I161 WeakPolarHBondContact O-CA 3.46Å; H141-E162 HydrophobicContact CB-CB 4.4Å; H141-E162 PolarHBondContact N-O 2.97Å; H141-E162 PolarHBondContact O-N 3.29Å; H141-L164 HydrophobicContact CB-CD1 4.43Å; H141-L164 HydrophobicContact CB-CD2 3.9Å; H141-L164 HydrophobicContact CB-CG 4.14Å
142	W	97.8	Very high	92.8	Very high	2 Å²	2	63 Å²	63	1%	0.008	31%	0.312	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-87.5	130.5	175.3	-72.5	47.7	0	0	0	110.9	M40 F72 I76 L127 N131 Y135 I159 L160 I161	M40-W142 HydrophobicContact SD-CH2 4.18Å; M40-W142 HydrophobicContact SD-CZ3 4.33Å; F72-W142 AromaticContact CD2-CH2 3.73Å; F72-W142 HydrophobicContact CD2-CH2 3.73Å; F72-W142 AromaticContact CD2-CZ2 3.53Å; F72-W142 HydrophobicContact CD2-CZ2 3.53Å; F72-W142 AromaticContact CE2-CH2 3.54Å; F72-W142 HydrophobicContact CE2-CH2 3.54Å; F72-W142 AromaticContact CE2-CZ2 3.61Å; F72-W142 HydrophobicContact CE2-CZ2 3.61Å; F72-W142 HydrophobicContact CZ-CH2 4.33Å; I76-W142 HydrophobicContact CB-CH2 4.5Å; I76-W142 HydrophobicContact CD1-CZ3 4.17Å; L127-W142 HydrophobicContact CD2-CB 4.14Å; L127-W142 HydrophobicContact CD2-CE3 3.77Å; N131-W142 PolarHBondContact ND2-N 3.43Å; N131-W142 PolarHBondContact ND2-O 3.09Å; N131-W142 WeakPolarHBondContact OD1-CB 3.42Å; N131-W142 PolarHBondContact OD1-N 3.01Å; Y135-W142 AromaticContact CD1-CD1 3.69Å; Y135-W142 AromaticContact CD1-NE1 3.18Å; Y135-W142 AromaticContact CD2-CD1 3.84Å; Y135-W142 HydrophobicContact CD2-CG 4.4Å; Y135-W142 AromaticContact CD2-NE1 3.8Å; Y135-W142 AromaticContact CE1-CE2 3.63Å; Y135-W142 AromaticContact CE1-CZ2 3.8Å; Y135-W142 HydrophobicContact CE1-CZ2 3.8Å; Y135-W142 AromaticContact CE1-NE1 3.09Å; Y135-W142 HydrophobicContact CE2-CD2 4.39Å; Y135-W142 AromaticContact CE2-CE2 3.87Å; Y135-W142 HydrophobicContact CE2-CZ2 4.18Å; Y135-W142 AromaticContact CE2-NE1 3.75Å; Y135-W142 AromaticContact CG-CD1 3.6Å; Y135-W142 AromaticContact CG-NE1 3.55Å; Y135-W142 AromaticContact CZ-CE2 3.5Å; Y135-W142 VanDerWaalsContact CZ-CE2 3.5Å; Y135-W142 AromaticContact CZ-CZ2 3.5Å; Y135-W142 VanDerWaalsContact CZ-CZ2 3.5Å; Y135-W142 AromaticContact CZ-NE1 3.41Å; Y135-W142 VanDerWaalsContact OH-CZ2 3.3Å; Y135-W142 WeakPolarHBondContact OH-CZ2 3.35Å; W142-I159 HydrophobicContact CD2-CG2 4.31Å; W142-I159 HydrophobicContact CE3-CG2 3.65Å; W142-I159 HydrophobicContact CZ3-CG2 4.18Å; W142-L160 CarbonylContact C-O 3.46Å; W142-L160 VanDerWaalsContact CA-O 3.28Å; W142-L160 WeakPolarHBondContact CA-O 3.49Å; W142-I161 HydrophobicContact CD2-CD1 4.14Å; W142-I161 HydrophobicContact CD2-CG1 3.92Å; W142-I161 VanDerWaalsContact CE2-CD1 3.48Å; W142-I161 HydrophobicContact CG-CG1 4.06Å; W142-I161 HydrophobicContact CH2-CD1 4.19Å; W142-I161 HydrophobicContact CZ2-CD1 3.53Å; W142-I161 HydrophobicContact CZ2-CG1 4.24Å
143	K	96.6	Very high	92	Very high	70 Å²	70	65 Å²	65	30%	0.304	32%	0.322	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-141.8	147.8	173.3	68.5	-177.1	-173.4	-164.6	0	112.7	I159 L160 E162	K143-I159 CarbonylContact O-C 3.54Å; K143-I159 WeakPolarHBondContact O-CA 3.42Å; K143-L160 HydrophobicContact CG-CB 3.93Å; K143-L160 HydrophobicContact CG-CD1 4.48Å; K143-L160 PolarHBondContact N-O 3.07Å; K143-L160 PolarHBondContact O-N 3.27Å; K143-E162 WeakPolarHBondContact CD-OE2 3.43Å; K143-E162 WeakPolarHBondContact CE-OE1 3.38Å; K143-E162 WeakPolarHBondContact CE-OE2 3.34Å; K143-E162 IonicContact NZ-OE1 2.71Å; K143-E162 PolarHBondContact NZ-OE1 3.13Å; K143-E162 IonicContact NZ-OE2 3.57Å; K143-E162 PolarHBondContact NZ-OE2 3.02Å
144	L	96.7	Very high	91.5	Very high	17 Å²	17	67.8 Å²	67.8	9%	0.089	34%	0.34	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-85.4	117.3	170.5	-171.2	71.2	0	0	0	108.7	F55 R120 I123 Q124 L127 Y157 I159	F55-L144 HydrophobicContact CE2-CD1 4.48Å; F55-L144 HydrophobicContact CZ-CD1 4.01Å; R120-L144 HydrophobicContact CB-CD2 4.38Å; R120-L144 HydrophobicContact CG-CD2 4.31Å; I123-L144 HydrophobicContact CB-CD2 4.36Å; I123-L144 HydrophobicContact CG2-CD1 4.37Å; I123-L144 HydrophobicContact CG2-CD2 4.18Å; Q124-L144 HydrophobicContact CG-CB 4.16Å; Q124-L144 HydrophobicContact CG-CD2 4.33Å; L127-L144 HydrophobicContact CD1-CB 3.97Å; L144-Y157 HydrophobicContact CD2-CD1 4.21Å; L144-Y157 HydrophobicContact CG-CD1 4.05Å; L144-I159 HydrophobicContact CD1-CG1 4.22Å
145	S	95.4	Very high	91.2	Very high	32 Å²	32	70.2 Å²	70.2	22%	0.224	35%	0.352	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-123	152.8	-178.2	-170.4	0	0	0	0	111.6	Y157 V158 L160	S145-Y157 CarbonylContact O-C 3.51Å; S145-Y157 VanDerWaalsContact O-CA 3.31Å; S145-Y157 WeakPolarHBondContact O-CA 3.42Å; S145-V158 PolarHBondContact N-O 3.48Å; S145-V158 PolarHBondContact O-N 3.33Å; S145-L160 VanDerWaalsContact CB-CD1 3.42Å
146	K	93.8	Very high	91	Very high	113 Å²	113	71.8 Å²	71.8	49%	0.491	36%	0.359	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.3	119.3	176.5	-164.7	-175.2	176.7	-178.5	0	108.4	M155 E156 Y157	K146-M155 HydrophobicContact CD-CB 4.39Å; K146-M155 HydrophobicContact CD-CE 4.12Å; K146-M155 HydrophobicContact CG-CB 4.25Å; K146-M155 HydrophobicContact CG-CE 3.8Å; K146-E156 CarbonylContact C-O 3.55Å; K146-E156 WeakPolarHBondContact CA-O 3.43Å; K146-Y157 HydrophobicContact CB-CD1 4.21Å; K146-Y157 HydrophobicContact CB-CE1 3.86Å; K146-Y157 HydrophobicContact CG-CE1 4.16Å
147	R	92.9	Very high	90.9	Very high	80 Å²	80	69.7 Å²	69.7	30%	0.302	35%	0.348	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-128	162.3	178.7	-69.5	-157.4	178.6	-165.3	4.1	111.2	M155 E156 V158	R147-M155 CarbonylContact O-C 3.56Å; R147-M155 WeakPolarHBondContact O-CA 3.39Å; R147-E156 PolarHBondContact N-O 3.34Å; R147-E156 PolarHBondContact O-N 2.9Å; R147-E156 VanDerWaalsContact O-O 3.13Å; R147-V158 HydrophobicContact CB-CG2 4.12Å; R147-V158 HydrophobicContact CG-CG2 3.8Å
148	K	90.5	Very high	90.9	Very high	117 Å²	117	61.9 Å²	61.9	51%	0.509	31%	0.314	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-73.9	135	171.1	-165.3	178.1	177.9	-175	0	108.5	N153 M155	K148-N153 WeakPolarHBondContact CE-OD1 3.46Å; K148-N153 PolarHBondContact NZ-OD1 3.38Å; K148-M155 HydrophobicContact CB-SD 4.2Å
149	C	84.8	Confident	91.1	Very high	19 Å²	19	59.5 Å²	59.5	13%	0.128	30%	0.302	C	S	.	.			trans	-65.1	143.4	172.6	-167.8	0	0	0	0	109	S151 S152 M154 E156	C149-S151 PolarHBondContact SG-OG 2.92Å; C149-S151 VanDerWaalsContact SG-OG 3.38Å; C149-S152 CarbonylContact C-O 3.05Å; C149-S152 WeakPolarHBondContact CB-O 3.17Å; C149-S152 WeakPolarHBondContact CB-OG 3.46Å; C149-M154 VanDerWaalsContact CB-O 3.31Å; C149-M154 WeakPolarHBondContact CB-O 3.44Å; C149-M154 PolarHBondContact N-O 3.39Å; C149-E156 HydrophobicContact CB-CG 4.18Å; C149-E156 PolarHBondContact SG-OE2 3.02Å
150	E	81	Confident	91.2	Very high	160 Å²	160	59 Å²	59	75%	0.748	30%	0.296	S	S	*	.	S	Bend	trans	-74.3	-36.6	178.4	-82.6	166.9	-163.6	0	0	111.8	R41	R41-E150 IonicContact CZ-OE1 3.63Å; R41-E150 IonicContact NE-OE1 2.91Å; R41-E150 VanDerWaalsContact NH2-CG 3.33Å; R41-E150 IonicContact NH2-OE1 3.46Å; R41-E150 PolarHBondContact NH2-OE1 3.3Å; R41-E150 IonicContact NH2-OE2 3.91Å
151	S	80.6	Confident	91.2	Very high	114 Å²	114	59 Å²	59	80%	0.797	30%	0.296	S	S	*	.	S	Bend	trans	-89	-8.1	-176.4	57.8	0	0	0	0	114	C149	C149-S151 PolarHBondContact SG-OG 2.92Å; C149-S151 VanDerWaalsContact SG-OG 3.38Å
152	S	78.4	Confident	91.2	Very high	35 Å²	35	59 Å²	59	25%	0.245	30%	0.296	C	S	.	.	S	Bend	trans	-148.9	156.7	179.7	71.1	0	0	0	0	111.9	C149 M154	C149-S152 CarbonylContact C-O 3.05Å; C149-S152 WeakPolarHBondContact CB-O 3.17Å; C149-S152 WeakPolarHBondContact CB-OG 3.46Å; S152-M154 PolarHBondContact O-N 2.86Å; S152-M154 PolarHBondContact OG-N 3.09Å
153	N	80.9	Confident	90.9	Very high	137 Å²	137	59.9 Å²	59.9	73%	0.733	30%	0.3	S	S	*	.	S	Bend	trans	-71.9	5.6	173.5	-74.7	-46.8	0	0	0	113.7	K148	K148-N153 WeakPolarHBondContact CE-OD1 3.46Å; K148-N153 PolarHBondContact NZ-OD1 3.38Å
154	M	86.2	Confident	90.7	Very high	137 Å²	137	59.7 Å²	59.7	68%	0.675	30%	0.302	S	S	*	.	S	Bend	trans	-78.4	151.4	179.4	-65.5	-168.9	-98.5	0	0	111.5	C149 S152	C149-M154 VanDerWaalsContact CB-O 3.31Å; C149-M154 WeakPolarHBondContact CB-O 3.44Å; C149-M154 PolarHBondContact N-O 3.39Å; S152-M154 PolarHBondContact O-N 2.86Å; S152-M154 PolarHBondContact OG-N 3.09Å
155	M	90.8	Very high	89.9	Confident	84 Å²	84	62.9 Å²	62.9	41%	0.414	32%	0.324	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-87	138.3	171	-61.7	-64.5	-65.1	0	0	110	G50 K146 R147 K148	G50-M155 VanDerWaalsContact CA-O 3.3Å; G50-M155 WeakPolarHBondContact CA-O 3.44Å; K146-M155 HydrophobicContact CD-CB 4.39Å; K146-M155 HydrophobicContact CD-CE 4.12Å; K146-M155 HydrophobicContact CG-CB 4.25Å; K146-M155 HydrophobicContact CG-CE 3.8Å; R147-M155 CarbonylContact O-C 3.56Å; R147-M155 WeakPolarHBondContact O-CA 3.39Å; K148-M155 HydrophobicContact CB-SD 4.2Å
156	E	93	Very high	88.6	Confident	34 Å²	34	68.8 Å²	68.8	16%	0.159	35%	0.345	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-127.6	155.8	176.4	60.6	174.9	-147.8	0	0	111.9	R41 G50 K146 R147 C149 V158	R41-E156 IonicContact CZ-OE1 3.98Å; R41-E156 IonicContact NE-OE1 3.49Å; R41-E156 IonicContact NH1-OE1 2.93Å; R41-E156 PolarHBondContact NH1-OE1 2.87Å; G50-E156 CarbonylContact O-C 3.58Å; G50-E156 WeakPolarHBondContact O-CA 3.47Å; K146-E156 CarbonylContact C-O 3.55Å; K146-E156 WeakPolarHBondContact CA-O 3.43Å; R147-E156 PolarHBondContact N-O 3.34Å; R147-E156 PolarHBondContact O-N 2.9Å; R147-E156 VanDerWaalsContact O-O 3.13Å; C149-E156 HydrophobicContact CB-CG 4.18Å; C149-E156 PolarHBondContact SG-OE2 3.02Å; E156-V158 HydrophobicContact CG-CG1 4.06Å; E156-V158 WeakPolarHBondContact OE1-CG1 3.27Å
157	Y	94.3	Very high	87.1	Confident	29 Å²	29	72.5 Å²	72.5	11%	0.114	36%	0.358	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.8	123.3	170.4	-76	-79.5	0	0	0	109.4	G50 L51 F55 R120 L144 S145 K146	G50-Y157 PolarHBondContact O-N 3.5Å; L51-Y157 HydrophobicContact CB-CD2 4.13Å; L51-Y157 HydrophobicContact CD1-CG 4.34Å; F55-Y157 WeakPolarHBondContact CE1-O 3.37Å; R120-Y157 PolarHBondContact NH1-OH 3.12Å; L144-Y157 HydrophobicContact CD2-CD1 4.21Å; L144-Y157 HydrophobicContact CG-CD1 4.05Å; S145-Y157 CarbonylContact O-C 3.51Å; S145-Y157 VanDerWaalsContact O-CA 3.31Å; S145-Y157 WeakPolarHBondContact O-CA 3.42Å; K146-Y157 HydrophobicContact CB-CD1 4.21Å; K146-Y157 HydrophobicContact CB-CE1 3.86Å; K146-Y157 HydrophobicContact CG-CE1 4.16Å
158	V	95.3	Very high	85.4	Confident	0 Å²	0	73 Å²	73	0%	0	37%	0.371	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-117.9	152.7	177.5	-60.3	0	0	0	0	109.8	I39 R41 S145 R147 E156 L160	I39-V158 HydrophobicContact CG2-CB 4.04Å; I39-V158 HydrophobicContact CG2-CG1 4.27Å; I39-V158 HydrophobicContact CG2-CG2 4.1Å; R41-V158 HydrophobicContact CG-CG1 4.01Å; S145-V158 PolarHBondContact N-O 3.48Å; S145-V158 PolarHBondContact O-N 3.33Å; R147-V158 HydrophobicContact CB-CG2 4.12Å; R147-V158 HydrophobicContact CG-CG2 3.8Å; E156-V158 HydrophobicContact CG-CG1 4.06Å; E156-V158 WeakPolarHBondContact OE1-CG1 3.27Å; V158-L160 HydrophobicContact CG2-CD2 3.99Å; V158-L160 HydrophobicContact CG2-CG 4.27Å
159	I	96.9	Very high	84	Confident	0 Å²	0	75.2 Å²	75.2	0%	0	39%	0.387	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.3	127.3	167.9	-63.5	170.9	0	0	0	107.3	M40 F55 I76 V79 W142 K143 L144	M40-I159 HydrophobicContact CB-CB 4.14Å; M40-I159 PolarHBondContact N-O 2.88Å; M40-I159 PolarHBondContact O-N 3.12Å; M40-I159 HydrophobicContact SD-CG2 4.48Å; F55-I159 HydrophobicContact CB-CD1 4.31Å; F55-I159 HydrophobicContact CD1-CD1 4.1Å; F55-I159 HydrophobicContact CD1-CG1 4.2Å; F55-I159 HydrophobicContact CD2-CD1 3.58Å; F55-I159 HydrophobicContact CD2-CG1 4.24Å; F55-I159 HydrophobicContact CE1-CD1 4.36Å; F55-I159 HydrophobicContact CE1-CG1 4.05Å; F55-I159 HydrophobicContact CE2-CD1 3.84Å; F55-I159 HydrophobicContact CE2-CG1 4.06Å; F55-I159 HydrophobicContact CG-CD1 3.72Å; F55-I159 HydrophobicContact CG-CG1 4.31Å; F55-I159 HydrophobicContact CZ-CD1 4.23Å; F55-I159 HydrophobicContact CZ-CG1 3.98Å; I76-I159 HydrophobicContact CD1-CD1 3.85Å; V79-I159 HydrophobicContact CG1-CD1 4.04Å; W142-I159 HydrophobicContact CD2-CG2 4.31Å; W142-I159 HydrophobicContact CE3-CG2 3.65Å; W142-I159 HydrophobicContact CZ3-CG2 4.18Å; K143-I159 CarbonylContact O-C 3.54Å; K143-I159 WeakPolarHBondContact O-CA 3.42Å; L144-I159 HydrophobicContact CD1-CG1 4.22Å
160	L	96.7	Very high	82.5	Confident	3 Å²	3	83.8 Å²	83.8	2%	0.016	42%	0.423	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-105.2	136	172.8	-61.1	178.8	0	0	0	108.9	V38 I39 W142 K143 S145 V158 E162	V38-L160 WeakPolarHBondContact O-CA 3.46Å; I39-L160 HydrophobicContact CB-CD2 4.2Å; I39-L160 HydrophobicContact CG1-CD2 3.74Å; I39-L160 HydrophobicContact CG2-CD2 4.1Å; W142-L160 CarbonylContact C-O 3.46Å; W142-L160 VanDerWaalsContact CA-O 3.28Å; W142-L160 WeakPolarHBondContact CA-O 3.49Å; K143-L160 HydrophobicContact CG-CB 3.93Å; K143-L160 HydrophobicContact CG-CD1 4.48Å; K143-L160 PolarHBondContact N-O 3.07Å; K143-L160 PolarHBondContact O-N 3.27Å; S145-L160 VanDerWaalsContact CB-CD1 3.42Å; V158-L160 HydrophobicContact CG2-CD2 3.99Å; V158-L160 HydrophobicContact CG2-CG 4.27Å; L160-E162 HydrophobicContact CB-CG 4.5Å
161	I	96.8	Very high	81.1	Confident	0 Å²	0	85.3 Å²	85.3	0%	0	42%	0.421	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.2	104.3	169.9	-52.4	173.7	0	0	0	106.7	P37 V38 M40 L63 F72 L140 H141 W142	P37-I161 CarbonylContact C-O 3.52Å; P37-I161 VanDerWaalsContact CA-O 3.26Å; P37-I161 WeakPolarHBondContact CA-O 3.31Å; P37-I161 WeakPolarHBondContact CB-O 3.49Å; V38-I161 HydrophobicContact CB-CB 4.17Å; V38-I161 PolarHBondContact N-O 3.42Å; V38-I161 PolarHBondContact O-N 3.11Å; M40-I161 HydrophobicContact SD-CD1 3.81Å; L63-I161 HydrophobicContact CD1-CD1 3.71Å; L63-I161 HydrophobicContact CD2-CG2 4.22Å; F72-I161 HydrophobicContact CE2-CD1 4.02Å; L140-I161 HydrophobicContact CB-CG2 4.26Å; L140-I161 HydrophobicContact CD2-CG2 4.12Å; H141-I161 WeakPolarHBondContact O-CA 3.46Å; W142-I161 HydrophobicContact CD2-CD1 4.14Å; W142-I161 HydrophobicContact CD2-CG1 3.92Å; W142-I161 VanDerWaalsContact CE2-CD1 3.48Å; W142-I161 HydrophobicContact CG-CG1 4.06Å; W142-I161 HydrophobicContact CH2-CD1 4.19Å; W142-I161 HydrophobicContact CZ2-CD1 3.53Å; W142-I161 HydrophobicContact CZ2-CG1 4.24Å
162	E	95.3	Very high	80	Confident	57 Å²	57	85.6 Å²	85.6	27%	0.266	42%	0.421	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.1	148.2	-179.8	-48.3	-166	127.3	0	0	110.1	P37 L140 H141 K143 L160	P37-E162 HydrophobicContact CB-CG 4.03Å; L140-E162 CarbonylContact C-O 3.5Å; L140-E162 VanDerWaalsContact CA-O 3.3Å; L140-E162 WeakPolarHBondContact CA-O 3.4Å; H141-E162 HydrophobicContact CB-CB 4.4Å; H141-E162 PolarHBondContact N-O 2.97Å; H141-E162 PolarHBondContact O-N 3.29Å; K143-E162 WeakPolarHBondContact CD-OE2 3.43Å; K143-E162 WeakPolarHBondContact CE-OE1 3.38Å; K143-E162 WeakPolarHBondContact CE-OE2 3.34Å; K143-E162 IonicContact NZ-OE1 2.71Å; K143-E162 PolarHBondContact NZ-OE1 3.13Å; K143-E162 IonicContact NZ-OE2 3.57Å; K143-E162 PolarHBondContact NZ-OE2 3.02Å; L160-E162 HydrophobicContact CB-CG 4.5Å
163	F	93.2	Very high	78.7	Confident	19 Å²	19	95.5 Å²	95.5	8%	0.083	47%	0.471	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-90	126.7	173.2	-62.5	-92.8	0	0	0	108.3	C34 P35 E36 V38 V62 L63 L140	C34-F163 PolarHBondContact SG-O 2.88Å; P35-F163 HydrophobicContact CB-CD2 3.97Å; P35-F163 HydrophobicContact CB-CE2 4.22Å; P35-F163 HydrophobicContact CB-CG 4.39Å; P35-F163 HydrophobicContact CG-CB 3.74Å; P35-F163 HydrophobicContact CG-CD1 4.05Å; P35-F163 HydrophobicContact CG-CD2 3.61Å; P35-F163 HydrophobicContact CG-CE2 4.18Å; P35-F163 HydrophobicContact CG-CG 3.53Å; E36-F163 WeakPolarHBondContact O-CE2 3.35Å; V38-F163 HydrophobicContact CG2-CE2 4.24Å; V38-F163 HydrophobicContact CG2-CZ 4.27Å; V62-F163 HydrophobicContact CG1-CZ 4.02Å; L63-F163 HydrophobicContact CD2-CE1 4.41Å; L63-F163 HydrophobicContact CD2-CZ 4.2Å; L140-F163 HydrophobicContact CD2-CD1 3.52Å; L140-F163 HydrophobicContact CD2-CE1 3.63Å; L140-F163 HydrophobicContact CD2-CG 4.26Å; L140-F163 HydrophobicContact CD2-CZ 4.44Å
164	L	90.6	Very high	78.6	Confident	66 Å²	66	93.4 Å²	93.4	35%	0.346	46%	0.458	S	S	.	.	P	Polyproline II helix	trans	-81.2	133.1	175.7	-63.7	175.7	0	0	0	108.6	G139 H141 K166	G139-L164 PolarHBondContact O-N 3.09Å; H141-L164 HydrophobicContact CB-CD1 4.43Å; H141-L164 HydrophobicContact CB-CD2 3.9Å; H141-L164 HydrophobicContact CB-CG 4.14Å; L164-K166 PolarHBondContact O-N 3.38Å
165	P	80.9	Confident	78.2	Confident	85 Å²	85	91.1 Å²	91.1	55%	0.552	45%	0.446	S	S	*	.	P	Polyproline II helix	trans	-60.9	132.6	178.7	25.1	-32.6	0	0	0	109.5
166	K	68.1	Low	77.5	Confident	155 Å²	155	91.5 Å²	91.5	67%	0.674	45%	0.448	S	S	*	.	P	Polyproline II helix	trans	-94.5	123	169.1	-67.3	-171.5	178.6	-171.6	0	107.5	L164	L164-K166 PolarHBondContact O-N 3.38Å
167	Y	61.8	Low	76.6	Confident	192 Å²	192	94.9 Å²	94.9	75%	0.753	47%	0.465	S	S	*	.	P	Polyproline II helix	trans	-58.4	126.1	169.1	-65.5	-81.1	0	0	0	108.4	I169	Y167-I169 PolarHBondContact O-N 2.93Å
168	P	58.5	Low	75.5	Confident	91 Å²	91	99 Å²	99	59%	0.591	49%	0.487	S	S	*	.	P	Polyproline II helix	trans	-64.2	121	173.7	25.3	-30	0	0	0	108.2	L30 F170	L30-P168 HydrophobicContact CD2-CG 4.44Å; P168-F170 PolarHBondContact O-N 3.35Å
169	I	59.3	Low	74.2	Confident	163 Å²	163	105.6 Å²	105.6	84%	0.836	52%	0.519	S	S	*	.			trans	-77.6	-3.5	-178.3	-51	171.9	0	0	0	110.9	Y167 R171	Y167-I169 PolarHBondContact O-N 2.93Å; I169-R171 VanDerWaalsContact C-N 3.3Å; I169-R171 PolarHBondContact O-N 3.27Å; I169-R171 VanDerWaalsContact O-N 3.11Å
170	F	54.8	Low	72.5	Confident	199 Å²	199	113.1 Å²	113.1	87%	0.873	56%	0.556	S	S	*	*			trans	-87.7	55	-178.5	-67.9	-78	0	0	0	113	P168	P168-F170 PolarHBondContact O-N 3.35Å
171	R	50.2	Low	70.7	Confident	191 Å²	191	121.6 Å²	121.6	72%	0.721	60%	0.598	S	S	*	*			trans	-97.1	108.4	153.7	-88.5	-172.7	177.4	167.2	-1.2	107.1	I169	I169-R171 VanDerWaalsContact C-N 3.3Å; I169-R171 PolarHBondContact O-N 3.27Å; I169-R171 VanDerWaalsContact O-N 3.11Å
172	P	58.3	Low	68.5	Low	121 Å²	121	131.8 Å²	131.8	79%	0.786	65%	0.648	S	S	*	*			trans	-64.4	134.3	161.1	26.9	-28	0	0	0	108.1
173	D	51.3	Low	66.1	Low	242 Å²	242	138.5 Å²	138.5	100%	1.294	68%	0.683	S	S	*	*			trans	-61.3	0	170.9	-66.7	-35	0	0	0	111.7

Retrieved 173 of 173 residues in 216.2 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).