A0A077Z952_TRITR Loading...

Divalent Anion:Na+ symporter family

AlphaFold DB (P60872), UniProt , Accession A0A077Z952, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 553 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M76.6Confident90.9Very high165 Ų16562.5 Ų62.581%0.81336%0.359SS*.  0152.20-71.9173.369.400107.5A5M1-A5 HydrophobicContact CB-CB 4.4Å; M1-A5 HydrophobicContact CE-CB 4.01Å
2S87.9Confident91.3Very high73 Ų7361.8 Ų61.851%0.5137%0.365SS..  trans-65.4154.5170.267.90000110.1I4 A5 L6S2-I4 PolarHBondContact O-N 3.13Å; S2-A5 PolarHBondContact O-N 3.11Å; S2-A5 WeakPolarHBondContact OG-CB 3.42Å; S2-A5 PolarHBondContact OG-N 2.86Å; S2-A5 VanDerWaalsContact OG-N 3.12Å; S2-L6 PolarHBondContact O-N 3.48Å
3D87.1Confident91.8Very high107 Ų10763.5 Ų63.557%0.57237%0.371SS*.Hα-helixtrans-56.7-36.1178.1-64.7-12.4000112T7D3-T7 VanDerWaalsContact O-CB 3.32Å; D3-T7 WeakPolarHBondContact O-CB 3.35Å; D3-T7 PolarHBondContact O-N 2.9Å; D3-T7 PolarHBondContact O-OG1 3.32Å
4I88.8Confident92.2Very high106 Ų10658.9 Ų58.954%0.54435%0.345SS..Hα-helixtrans-61.9-51.9174.1-63.8177.7000110.2S2 L6 T7 V8 M58S2-I4 PolarHBondContact O-N 3.13Å; I4-L6 VanDerWaalsContact C-N 3.32Å; I4-L6 PolarHBondContact O-N 3.14Å; I4-T7 PolarHBondContact O-N 3.14Å; I4-V8 WeakPolarHBondContact O-CG2 3.18Å; I4-V8 PolarHBondContact O-N 3.1Å; I4-M58 HydrophobicContact CB-CE 4.41Å; I4-M58 HydrophobicContact CB-SD 4.27Å; I4-M58 HydrophobicContact CG1-SD 4.44Å; I4-M58 HydrophobicContact CG2-CE 3.51Å; I4-M58 HydrophobicContact CG2-SD 4Å
5A91.8Very high92.4Very high35 Ų3556.2 Ų56.229%0.28933%0.331SS..Hα-helixtrans-64.4-37.9-179.200000111.7M1 S2 S9M1-A5 HydrophobicContact CB-CB 4.4Å; M1-A5 HydrophobicContact CE-CB 4.01Å; S2-A5 PolarHBondContact O-N 3.11Å; S2-A5 WeakPolarHBondContact OG-CB 3.42Å; S2-A5 PolarHBondContact OG-N 2.86Å; S2-A5 VanDerWaalsContact OG-N 3.12Å; A5-S9 VanDerWaalsContact O-CB 3.3Å; A5-S9 WeakPolarHBondContact O-CB 3.29Å; A5-S9 PolarHBondContact O-N 2.82Å; A5-S9 PolarHBondContact O-OG 2.87Å
6L93.5Very high92.7Very high44 Ų4458.9 Ų58.923%0.2335%0.349CS..Hα-helixtrans-63.9-49.2175.3-178.264.6000111S2 I4 V8 S9 I10 L54S2-L6 PolarHBondContact O-N 3.48Å; I4-L6 VanDerWaalsContact C-N 3.32Å; I4-L6 PolarHBondContact O-N 3.14Å; L6-V8 PolarHBondContact O-N 3.07Å; L6-S9 PolarHBondContact O-N 3.44Å; L6-I10 HydrophobicContact CD1-CG1 4.36Å; L6-I10 WeakPolarHBondContact O-CG1 3.48Å; L6-I10 PolarHBondContact O-N 3.44Å; L6-L54 HydrophobicContact CD2-CD2 4.02Å; L6-L54 HydrophobicContact CG-CD2 3.9Å
7T93.5Very high92.9Very high0 Ų057.9 Ų57.90%034%0.343CS..Hα-helixtrans-60.8-45.4-179.5-55.60000111.4D3 I4 I10 L11 S55 M58 L59D3-T7 VanDerWaalsContact O-CB 3.32Å; D3-T7 WeakPolarHBondContact O-CB 3.35Å; D3-T7 PolarHBondContact O-N 2.9Å; D3-T7 PolarHBondContact O-OG1 3.32Å; I4-T7 PolarHBondContact O-N 3.14Å; T7-I10 PolarHBondContact O-N 3.39Å; T7-L11 HydrophobicContact CG2-CD1 4.24Å; T7-L11 WeakPolarHBondContact O-CG 3.48Å; T7-L11 PolarHBondContact O-N 2.95Å; T7-S55 PolarHBondContact OG1-N 3.22Å; T7-M58 HydrophobicContact CG2-CB 4.3Å; T7-M58 HydrophobicContact CG2-CG 4.19Å; T7-M58 HydrophobicContact CG2-SD 3.9Å; T7-L59 HydrophobicContact CG2-CD2 3.81Å; T7-L59 HydrophobicContact CG2-CG 4.08Å
8V93.5Very high93.1Very high70 Ų7054.7 Ų54.742%0.42432%0.324SS..Hα-helixtrans-63.3-43.1176.4172.90000111.5I4 L6 I10 L11 A12 M58I4-V8 WeakPolarHBondContact O-CG2 3.18Å; I4-V8 PolarHBondContact O-N 3.1Å; L6-V8 PolarHBondContact O-N 3.07Å; V8-I10 PolarHBondContact O-N 2.88Å; V8-L11 PolarHBondContact O-N 3.4Å; V8-A12 WeakPolarHBondContact O-CB 3.41Å; V8-A12 PolarHBondContact O-N 3.46Å; V8-M58 HydrophobicContact CG2-CE 3.45Å; V8-M58 VanDerWaalsContact CG2-CE 3.45Å; V8-M58 HydrophobicContact CG2-SD 4.09Å
9S95.1Very high93Very high59 Ų5955.5 Ų55.541%0.41333%0.326SS..Hα-helixtrans-63.3-40.5177.9-70.60000112.5A5 L6 A12 L13A5-S9 VanDerWaalsContact O-CB 3.3Å; A5-S9 WeakPolarHBondContact O-CB 3.29Å; A5-S9 PolarHBondContact O-N 2.82Å; A5-S9 PolarHBondContact O-OG 2.87Å; L6-S9 PolarHBondContact O-N 3.44Å; S9-A12 PolarHBondContact O-N 2.89Å; S9-L13 WeakPolarHBondContact O-CB 3.2Å; S9-L13 PolarHBondContact O-N 2.91Å
10I96.1Very high93.1Very high17 Ų1760.3 Ų60.39%0.08734%0.343CS..Hα-helixtrans-66.8-43.7175.7-66.8-60.3000110.9L6 T7 V8 A12 L13 V14 V43 V47 L54 L448L6-I10 HydrophobicContact CD1-CG1 4.36Å; L6-I10 WeakPolarHBondContact O-CG1 3.48Å; L6-I10 PolarHBondContact O-N 3.44Å; T7-I10 PolarHBondContact O-N 3.39Å; V8-I10 PolarHBondContact O-N 2.88Å; I10-A12 VanDerWaalsContact C-N 3.32Å; I10-A12 PolarHBondContact O-N 3.43Å; I10-L13 WeakPolarHBondContact O-CB 3.4Å; I10-L13 PolarHBondContact O-N 3.29Å; I10-L13 VanDerWaalsContact O-N 3.17Å; I10-V14 HydrophobicContact CG2-CG2 4.47Å; I10-V14 VanDerWaalsContact O-CG2 3.31Å; I10-V14 WeakPolarHBondContact O-CG2 3.48Å; I10-V14 PolarHBondContact O-N 3.2Å; I10-V43 HydrophobicContact CG2-CG1 4.06Å; I10-V47 HydrophobicContact CD1-CG2 4.08Å; I10-V47 HydrophobicContact CG2-CG2 3.97Å; I10-L54 HydrophobicContact CB-CD1 4.4Å; I10-L54 HydrophobicContact CG1-CD2 4.15Å; I10-L54 HydrophobicContact CG2-CD1 4.02Å; I10-L448 HydrophobicContact CG2-CD1 3.71Å; I10-L448 HydrophobicContact CG2-CD2 4.19Å
11L95.5Very high93.1Very high12 Ų1259.5 Ų59.56%0.06334%0.338CS..Hα-helixtrans-64.6-37176.1-71.1174.1000112.5T7 V8 L13 V14 A15 L59 I62 V445 L448T7-L11 HydrophobicContact CG2-CD1 4.24Å; T7-L11 WeakPolarHBondContact O-CG 3.48Å; T7-L11 PolarHBondContact O-N 2.95Å; V8-L11 PolarHBondContact O-N 3.4Å; L11-L13 VanDerWaalsContact C-N 3.33Å; L11-V14 WeakPolarHBondContact O-CB 3.41Å; L11-V14 PolarHBondContact O-N 3.42Å; L11-A15 WeakPolarHBondContact O-CB 3.47Å; L11-A15 PolarHBondContact O-N 3.31Å; L11-L59 HydrophobicContact CD1-CD2 4.07Å; L11-L59 HydrophobicContact CD2-CD2 3.94Å; L11-L59 HydrophobicContact CG-CD2 4.2Å; L11-I62 HydrophobicContact CD1-CD1 3.38Å; L11-I62 HydrophobicContact CD1-CG2 4.14Å; L11-V445 HydrophobicContact CD1-CG2 4.39Å; L11-V445 HydrophobicContact CD2-CG2 3.83Å; L11-L448 HydrophobicContact CD2-CD2 4.23Å
12A96.4Very high93.6Very high53 Ų5351.8 Ų51.844%0.43830%0.3SS..Hα-helixtrans-63-41.7172.700000111.2V8 S9 I10 A15 V16V8-A12 WeakPolarHBondContact O-CB 3.41Å; V8-A12 PolarHBondContact O-N 3.46Å; S9-A12 PolarHBondContact O-N 2.89Å; I10-A12 VanDerWaalsContact C-N 3.32Å; I10-A12 PolarHBondContact O-N 3.43Å; A12-A15 PolarHBondContact O-N 3.21Å; A12-V16 VanDerWaalsContact O-CG2 3.3Å; A12-V16 WeakPolarHBondContact O-CG2 3.42Å; A12-V16 PolarHBondContact O-N 3.47Å
13L97.3Very high93.5Very high84 Ų8454.3 Ų54.344%0.4431%0.308SS..Hα-helixtrans-62-45.4174.2-179.964.4000111.6S9 I10 L11 A15 V16 V17 V43S9-L13 WeakPolarHBondContact O-CB 3.2Å; S9-L13 PolarHBondContact O-N 2.91Å; I10-L13 WeakPolarHBondContact O-CB 3.4Å; I10-L13 PolarHBondContact O-N 3.29Å; I10-L13 VanDerWaalsContact O-N 3.17Å; L11-L13 VanDerWaalsContact C-N 3.33Å; L13-A15 VanDerWaalsContact C-N 3.33Å; L13-A15 PolarHBondContact O-N 3.43Å; L13-V16 PolarHBondContact O-N 3.12Å; L13-V17 HydrophobicContact CD1-CG2 4.06Å; L13-V17 HydrophobicContact CG-CG2 4.39Å; L13-V17 WeakPolarHBondContact O-CG2 3.27Å; L13-V17 PolarHBondContact O-N 3.35Å; L13-V43 HydrophobicContact CD2-CG1 4.16Å; L13-V43 HydrophobicContact CD2-CG2 4.38Å; L13-V43 HydrophobicContact CG-CG2 4.19Å
14V97.2Very high93.5Very high0 Ų053.4 Ų53.40%031%0.306CS..Hα-helixtrans-55.3-49.2174.1169.70000110.7I10 L11 V16 G18 V36 V43 L448I10-V14 HydrophobicContact CG2-CG2 4.47Å; I10-V14 VanDerWaalsContact O-CG2 3.31Å; I10-V14 WeakPolarHBondContact O-CG2 3.48Å; I10-V14 PolarHBondContact O-N 3.2Å; L11-V14 WeakPolarHBondContact O-CB 3.41Å; L11-V14 PolarHBondContact O-N 3.42Å; V14-V16 PolarHBondContact O-N 2.89Å; V14-G18 WeakPolarHBondContact O-CA 3.49Å; V14-G18 PolarHBondContact O-N 3.47Å; V14-V36 HydrophobicContact CG1-CG1 4.46Å; V14-V43 HydrophobicContact CG2-CB 3.75Å; V14-V43 HydrophobicContact CG2-CG1 3.72Å; V14-V43 HydrophobicContact CG2-CG2 4.2Å; V14-L448 HydrophobicContact CG2-CD1 3.9Å
15A95.9Very high93.1Very high18 Ų1855.7 Ų55.715%0.14931%0.312CS..Hα-helixtrans-61.7-43.7179.200000111.6L11 A12 L13 G18 L19 V440L11-A15 WeakPolarHBondContact O-CB 3.47Å; L11-A15 PolarHBondContact O-N 3.31Å; A12-A15 PolarHBondContact O-N 3.21Å; L13-A15 VanDerWaalsContact C-N 3.33Å; L13-A15 PolarHBondContact O-N 3.43Å; A15-G18 PolarHBondContact O-N 3.2Å; A15-L19 WeakPolarHBondContact O-CB 3.16Å; A15-L19 WeakPolarHBondContact O-CG 3.31Å; A15-L19 PolarHBondContact O-N 2.7Å; A15-V440 HydrophobicContact CB-CG1 3.71Å
16V96.8Very high92.3Very high100 Ų10061.1 Ų61.161%0.60633%0.33SS*.Hα-helixtrans-62-53.5178.1168.10000111.4A12 L13 V14 G18 F20A12-V16 VanDerWaalsContact O-CG2 3.3Å; A12-V16 WeakPolarHBondContact O-CG2 3.42Å; A12-V16 PolarHBondContact O-N 3.47Å; L13-V16 PolarHBondContact O-N 3.12Å; V14-V16 PolarHBondContact O-N 2.89Å; V16-G18 VanDerWaalsContact C-N 3.3Å; V16-G18 PolarHBondContact O-N 2.92Å; V16-F20 VanDerWaalsContact O-CB 3.29Å; V16-F20 WeakPolarHBondContact O-CB 3.27Å; V16-F20 PolarHBondContact O-N 3.21Å
17V97.1Very high91.4Very high42 Ų4269.4 Ų69.426%0.25536%0.358SS..Hα-helixtrans-61.4-43.9179.7173.50000110.2L13 F20 I21 V43L13-V17 HydrophobicContact CD1-CG2 4.06Å; L13-V17 HydrophobicContact CG-CG2 4.39Å; L13-V17 WeakPolarHBondContact O-CG2 3.27Å; L13-V17 PolarHBondContact O-N 3.35Å; V17-F20 WeakPolarHBondContact O-CB 3.41Å; V17-F20 PolarHBondContact O-N 2.97Å; V17-I21 HydrophobicContact CG1-CD1 3.8Å; V17-I21 VanDerWaalsContact O-CG1 3.28Å; V17-I21 WeakPolarHBondContact O-CG1 3.43Å; V17-I21 PolarHBondContact O-N 3.16Å; V17-V43 HydrophobicContact CB-CG2 4.42Å; V17-V43 HydrophobicContact CG2-CG2 4.23Å
18G94.9Very high90.2Very high0 Ų072.4 Ų72.40%039%0.389CS..Hα-helixtrans-66.3-46.4-177.500000114.6V14 A15 V16 F20 I21 G22 G35V14-G18 WeakPolarHBondContact O-CA 3.49Å; V14-G18 PolarHBondContact O-N 3.47Å; A15-G18 PolarHBondContact O-N 3.2Å; V16-G18 VanDerWaalsContact C-N 3.3Å; V16-G18 PolarHBondContact O-N 2.92Å; G18-F20 VanDerWaalsContact C-N 3.3Å; G18-I21 PolarHBondContact O-N 3.39Å; G18-G22 PolarHBondContact O-N 3.49Å; G18-G35 VanDerWaalsContact CA-O 3.26Å; G18-G35 WeakPolarHBondContact CA-O 3.39Å; G18-G35 CarbonylContact O-C 3.57Å; G18-G35 WeakPolarHBondContact O-CA 3.33Å
19L92.8Very high89Confident70 Ų7072.5 Ų72.537%0.36639%0.386SS..Hα-helixtrans-67-33.9174.8-69.8172000111.5A15 G22 N23 V36 V440A15-L19 WeakPolarHBondContact O-CB 3.16Å; A15-L19 WeakPolarHBondContact O-CG 3.31Å; A15-L19 PolarHBondContact O-N 2.7Å; L19-G22 PolarHBondContact O-N 3.06Å; L19-N23 WeakPolarHBondContact O-CB 3.48Å; L19-N23 PolarHBondContact O-N 3.23Å; L19-N23 PolarHBondContact O-ND2 3.48Å; L19-V36 HydrophobicContact CD2-CG2 3.85Å; L19-V36 HydrophobicContact CG-CG2 4.01Å; L19-V440 HydrophobicContact CD2-CG2 4.09Å
20F94.6Very high87.9Confident150 Ų15070.6 Ų70.666%0.65838%0.376SS*.Hα-helixtrans-61.4-52.9172.4-179.1-96.5000111V16 V17 G18 G22 N23 V24V16-F20 VanDerWaalsContact O-CB 3.29Å; V16-F20 WeakPolarHBondContact O-CB 3.27Å; V16-F20 PolarHBondContact O-N 3.21Å; V17-F20 WeakPolarHBondContact O-CB 3.41Å; V17-F20 PolarHBondContact O-N 2.97Å; G18-F20 VanDerWaalsContact C-N 3.3Å; F20-G22 VanDerWaalsContact C-N 3.27Å; F20-G22 PolarHBondContact O-N 3.49Å; F20-N23 PolarHBondContact O-N 2.97Å; F20-V24 PolarHBondContact O-N 3Å
21I92Very high86.9Confident45 Ų4572.3 Ų72.323%0.23139%0.385CS..Hα-helixtrans-56.6-43.6175.5-68.5165.6000110.8V17 G18 N23 V24 L31 I42V17-I21 HydrophobicContact CG1-CD1 3.8Å; V17-I21 VanDerWaalsContact O-CG1 3.28Å; V17-I21 WeakPolarHBondContact O-CG1 3.43Å; V17-I21 PolarHBondContact O-N 3.16Å; G18-I21 PolarHBondContact O-N 3.39Å; I21-N23 VanDerWaalsContact C-N 3.29Å; I21-N23 PolarHBondContact O-N 3.33Å; I21-V24 WeakPolarHBondContact O-CB 3.12Å; I21-V24 PolarHBondContact O-N 2.94Å; I21-L31 HydrophobicContact CG2-CD1 3.99Å; I21-I42 HydrophobicContact CD1-CD1 3.63Å
22G86.8Confident86.1Confident3 Ų373.4 Ų73.43%0.03140%0.399CS..Hα-helixtrans-59.7-35.8179.400000114.8G18 L19 F20 G32G18-G22 PolarHBondContact O-N 3.49Å; L19-G22 PolarHBondContact O-N 3.06Å; F20-G22 VanDerWaalsContact C-N 3.27Å; F20-G22 PolarHBondContact O-N 3.49Å; G22-G32 WeakPolarHBondContact CA-O 3.48Å; G22-G32 WeakPolarHBondContact O-CA 3.48Å; G22-G32 PolarHBondContact O-N 2.92Å
23N87.4Confident85.3Confident125 Ų12573.3 Ų73.367%0.66839%0.39SS*.Hα-helixtrans-79.9-16.1179.3-82.2-30.3000113.7L19 F20 I21 K25L19-N23 WeakPolarHBondContact O-CB 3.48Å; L19-N23 PolarHBondContact O-N 3.23Å; L19-N23 PolarHBondContact O-ND2 3.48Å; F20-N23 PolarHBondContact O-N 2.97Å; I21-N23 VanDerWaalsContact C-N 3.29Å; I21-N23 PolarHBondContact O-N 3.33Å; N23-K25 PolarHBondContact O-N 3.37Å
24V87.1Confident84.5Confident88 Ų8869.5 Ų69.553%0.53337%0.372SS..  trans-68118.3173.8-179.70000108.9F20 I21F20-V24 PolarHBondContact O-N 3Å; I21-V24 WeakPolarHBondContact O-CB 3.12Å; I21-V24 PolarHBondContact O-N 2.94Å
25K79.7Confident84.1Confident154 Ų15469.5 Ų69.567%0.6737%0.372SS*.EExtended strand (participates in β ladder)trans-104.3126.8178.1-62.9-179.5-175.41790109.8N23 I29N23-K25 PolarHBondContact O-N 3.37Å; K25-I29 WeakPolarHBondContact CA-O 3.15Å
26F76Confident83.9Confident150 Ų15068.7 Ų68.766%0.65837%0.365SS*.EExtended strand (participates in β ladder)trans-105.8118.4167.6-172.9-102.8000109.2G28 I29F26-G28 PolarHBondContact O-N 3.46Å; F26-I29 PolarHBondContact N-O 3.44Å; F26-I29 PolarHBondContact O-N 2.66Å
27R73.3Confident83.7Confident217 Ų21764 Ų6482%0.81934%0.336SS*.THydrogen-bonded Turntrans50.937.8-176.2-68-173.4149.899.9-2.3114.1I29R27-I29 VanDerWaalsContact C-N 3.25Å; R27-I29 PolarHBondContact O-N 3.09Å
28G69.5Low83.5Confident64 Ų6463.7 Ų63.766%0.6633%0.331SS*.THydrogen-bonded Turntrans81.9-7178.900000115.2F26F26-G28 PolarHBondContact O-N 3.46Å
29I68.4Low83.5Confident72 Ų7263.7 Ų63.737%0.36933%0.331SS..EExtended strand (participates in β ladder)trans-98.3126.3174.5-58.3158.1000107.8K25 F26 R27 L172K25-I29 WeakPolarHBondContact CA-O 3.15Å; F26-I29 PolarHBondContact N-O 3.44Å; F26-I29 PolarHBondContact O-N 2.66Å; R27-I29 VanDerWaalsContact C-N 3.25Å; R27-I29 PolarHBondContact O-N 3.09Å; I29-L172 HydrophobicContact CD1-CD1 3.63Å; I29-L172 HydrophobicContact CG1-CD1 4.28Å; I29-L172 HydrophobicContact CG2-CD1 4.3Å
30G70.8Confident83.6Confident18 Ų1860.3 Ų60.319%0.18631%0.314CS..EExtended strand (participates in β ladder)trans-124.5157.4174.100000110.4G32G30-G32 PolarHBondContact O-N 3Å
31L75.2Confident83.6Confident54 Ų5453.7 Ų53.728%0.28329%0.285SS..  trans-68.8-20.7174.2-68170.7000111.9I21 G34 F38 I168I21-L31 HydrophobicContact CG2-CD1 3.99Å; L31-G34 PolarHBondContact O-N 3.12Å; L31-G34 VanDerWaalsContact O-N 3.17Å; L31-F38 HydrophobicContact CD1-CD2 4.01Å; L31-F38 HydrophobicContact CD1-CE2 4.29Å; L31-F38 HydrophobicContact CD2-CE2 4.34Å; L31-I168 HydrophobicContact CD2-CD1 4.28Å
32G78.9Confident83.7Confident34 Ų3455 Ų5535%0.35129%0.292SS..G310 helixtrans57.8-141.2-176.100000110.7G22 G30 G34 G35G22-G32 WeakPolarHBondContact CA-O 3.48Å; G22-G32 WeakPolarHBondContact O-CA 3.48Å; G22-G32 PolarHBondContact O-N 2.92Å; G30-G32 PolarHBondContact O-N 3Å; G32-G34 PolarHBondContact O-N 2.9Å; G32-G34 VanDerWaalsContact O-N 3.11Å; G32-G35 PolarHBondContact O-N 2.99Å
33I79.6Confident84.2Confident51 Ų5155.4 Ų55.426%0.26229%0.294SS..G310 helixtrans-59.9-23.9178.4-71.6144.8000112.9G35 V36 E436 I439 L443I33-G35 PolarHBondContact O-N 3.41Å; I33-G35 VanDerWaalsContact O-N 3.1Å; I33-V36 WeakPolarHBondContact O-CB 3.23Å; I33-V36 WeakPolarHBondContact O-CG2 3.18Å; I33-V36 PolarHBondContact O-N 3.21Å; I33-E436 HydrophobicContact CD1-CG 3.68Å; I33-I439 HydrophobicContact CG2-CB 4.32Å; I33-I439 HydrophobicContact CG2-CD1 3.99Å; I33-I439 HydrophobicContact CG2-CG1 3.94Å; I33-I439 HydrophobicContact CG2-CG2 3.44Å; I33-I439 VanDerWaalsContact CG2-CG2 3.44Å; I33-L443 HydrophobicContact CG2-CD1 4.37Å
34G79.9Confident84.6Confident5 Ų549.6 Ų49.65%0.05226%0.263CS..G310 helixtrans-57.8-21.9172.300000113.3L31 G32 V36 L37 F38L31-G34 PolarHBondContact O-N 3.12Å; L31-G34 VanDerWaalsContact O-N 3.17Å; G32-G34 PolarHBondContact O-N 2.9Å; G32-G34 VanDerWaalsContact O-N 3.11Å; G34-V36 PolarHBondContact O-N 2.95Å; G34-L37 WeakPolarHBondContact O-CB 3.49Å; G34-L37 PolarHBondContact O-N 3.35Å; G34-L37 VanDerWaalsContact O-N 3.15Å; G34-F38 WeakPolarHBondContact O-CD2 3.16Å
35G88.7Confident84.9Confident0 Ų047.6 Ų47.60%025%0.248CC..Hα-helixtrans-57-27171.900000113.9G18 G32 I33 L37 F38 G39G18-G35 VanDerWaalsContact CA-O 3.26Å; G18-G35 WeakPolarHBondContact CA-O 3.39Å; G18-G35 CarbonylContact O-C 3.57Å; G18-G35 WeakPolarHBondContact O-CA 3.33Å; G32-G35 PolarHBondContact O-N 2.99Å; I33-G35 PolarHBondContact O-N 3.41Å; I33-G35 VanDerWaalsContact O-N 3.1Å; G35-L37 VanDerWaalsContact C-N 3.29Å; G35-L37 PolarHBondContact O-N 2.83Å; G35-F38 PolarHBondContact O-N 3.34Å; G35-G39 PolarHBondContact O-N 3.45Å
36V93.4Very high85.6Confident0 Ų046.3 Ų46.30%024%0.243CC..Hα-helixtrans-61.6-36.8177-178.50000112.6V14 L19 I33 G34 G39 G40 V440 L443 S444V14-V36 HydrophobicContact CG1-CG1 4.46Å; L19-V36 HydrophobicContact CD2-CG2 3.85Å; L19-V36 HydrophobicContact CG-CG2 4.01Å; I33-V36 WeakPolarHBondContact O-CB 3.23Å; I33-V36 WeakPolarHBondContact O-CG2 3.18Å; I33-V36 PolarHBondContact O-N 3.21Å; G34-V36 PolarHBondContact O-N 2.95Å; V36-G39 PolarHBondContact O-N 3.34Å; V36-G40 PolarHBondContact O-N 3.2Å; V36-V440 HydrophobicContact CG1-CG1 4.4Å; V36-V440 HydrophobicContact CG2-CG2 4.13Å; V36-L443 HydrophobicContact CB-CB 4.12Å; V36-L443 HydrophobicContact CG1-CB 3.92Å; V36-S444 VanDerWaalsContact CG1-OG 3.29Å; V36-S444 WeakPolarHBondContact CG1-OG 3.4Å
37L92.2Very high86.5Confident1 Ų139.8 Ų39.81%0.00522%0.215CC..Hα-helixtrans-60.4-47.9174.4-179.372.7000111.3G34 G35 G40 I41 Y160 A161 L443 V446 G447G34-L37 WeakPolarHBondContact O-CB 3.49Å; G34-L37 PolarHBondContact O-N 3.35Å; G34-L37 VanDerWaalsContact O-N 3.15Å; G35-L37 VanDerWaalsContact C-N 3.29Å; G35-L37 PolarHBondContact O-N 2.83Å; L37-G40 WeakPolarHBondContact O-CA 3.48Å; L37-G40 PolarHBondContact O-N 3.06Å; L37-I41 HydrophobicContact CG-CD1 4.28Å; L37-I41 WeakPolarHBondContact O-CG1 3.39Å; L37-I41 PolarHBondContact O-N 3.26Å; L37-Y160 HydrophobicContact CD1-CD1 4.2Å; L37-Y160 HydrophobicContact CD1-CE1 4.26Å; L37-Y160 HydrophobicContact CD2-CD1 3.65Å; L37-Y160 HydrophobicContact CD2-CE1 3.46Å; L37-Y160 VanDerWaalsContact CD2-CE1 3.46Å; L37-Y160 HydrophobicContact CG-CE1 4.43Å; L37-A161 HydrophobicContact CD1-CB 4.28Å; L37-A161 HydrophobicContact CD2-CB 3.47Å; L37-A161 VanDerWaalsContact CD2-CB 3.47Å; L37-A161 HydrophobicContact CG-CB 3.94Å; L37-L443 HydrophobicContact CB-CD2 4.38Å; L37-L443 HydrophobicContact CD1-CD2 4.24Å; L37-V446 HydrophobicContact CD1-CB 4.46Å; L37-V446 HydrophobicContact CD1-CG1 3.8Å; L37-G447 WeakPolarHBondContact O-CA 3.32Å
38F92.3Very high87.3Confident36 Ų3632.8 Ų32.816%0.15820%0.199CC..Hα-helixtrans-70.6-37.5-179.5-64.3-76.2000112.3L31 G34 G35 G40 I41 I42 Y164 P165L31-F38 HydrophobicContact CD1-CD2 4.01Å; L31-F38 HydrophobicContact CD1-CE2 4.29Å; L31-F38 HydrophobicContact CD2-CE2 4.34Å; G34-F38 WeakPolarHBondContact O-CD2 3.16Å; G35-F38 PolarHBondContact O-N 3.34Å; F38-G40 VanDerWaalsContact C-N 3.25Å; F38-G40 PolarHBondContact O-N 3.47Å; F38-I41 HydrophobicContact CD1-CD1 4.36Å; F38-I41 PolarHBondContact O-N 3.05Å; F38-I42 VanDerWaalsContact O-CG1 3.29Å; F38-I42 WeakPolarHBondContact O-CG1 3.4Å; F38-I42 PolarHBondContact O-N 3.49Å; F38-Y164 HydrophobicContact CE2-CD1 4.06Å; F38-Y164 HydrophobicContact CZ-CD1 4.39Å; F38-P165 HydrophobicContact CE1-CG 4.21Å; F38-P165 HydrophobicContact CZ-CG 3.62Å
39G94.6Very high88.3Confident0 Ų036 Ų360%020%0.197CC..Hα-helixtrans-58.9-40.7169.500000111.6G35 V36 I42 V43G35-G39 PolarHBondContact O-N 3.45Å; V36-G39 PolarHBondContact O-N 3.34Å; G39-I42 PolarHBondContact O-N 2.89Å; G39-V43 WeakPolarHBondContact O-CB 3.26Å; G39-V43 WeakPolarHBondContact O-CG2 3.35Å; G39-V43 PolarHBondContact O-N 3.11Å
40G95.1Very high89.4Confident0 Ų035.6 Ų35.60%021%0.205CC..Hα-helixtrans-61.9-44.6173.800000112.4V36 L37 F38 G44 G447 L448V36-G40 PolarHBondContact O-N 3.2Å; L37-G40 WeakPolarHBondContact O-CA 3.48Å; L37-G40 PolarHBondContact O-N 3.06Å; F38-G40 VanDerWaalsContact C-N 3.25Å; F38-G40 PolarHBondContact O-N 3.47Å; G40-G44 WeakPolarHBondContact O-CA 3.38Å; G40-G44 PolarHBondContact O-N 2.85Å; G40-G447 CarbonylContact C-O 3.53Å; G40-G447 VanDerWaalsContact C-O 3.23Å; G40-G447 CarbonylContact O-C 3.57Å; G40-L448 WeakPolarHBondContact O-CA 3.45Å; G40-L448 PolarHBondContact O-N 2.93Å
41I94.1Very high90.2Very high10 Ų1037.5 Ų37.55%0.05123%0.225CC..Hα-helixtrans-61.3-46.6177.4-72.8163000111.2L37 F38 G44 H45 A161 G447 G451 F454L37-I41 HydrophobicContact CG-CD1 4.28Å; L37-I41 WeakPolarHBondContact O-CG1 3.39Å; L37-I41 PolarHBondContact O-N 3.26Å; F38-I41 HydrophobicContact CD1-CD1 4.36Å; F38-I41 PolarHBondContact O-N 3.05Å; I41-G44 PolarHBondContact O-N 3.13Å; I41-H45 WeakPolarHBondContact O-CB 3.37Å; I41-H45 PolarHBondContact O-N 3.07Å; I41-A161 HydrophobicContact CD1-CB 3.44Å; I41-A161 VanDerWaalsContact CD1-CB 3.44Å; I41-G447 WeakPolarHBondContact CA-O 3.36Å; I41-G447 PolarHBondContact N-O 2.96Å; I41-G451 VanDerWaalsContact O-CA 3.25Å; I41-G451 WeakPolarHBondContact O-CA 3.3Å; I41-F454 HydrophobicContact CD1-CD2 3.78Å; I41-F454 HydrophobicContact CD1-CE2 3.83Å; I41-F454 HydrophobicContact CD1-CG 4.26Å; I41-F454 HydrophobicContact CD1-CZ 4.36Å; I41-F454 HydrophobicContact CG1-CD2 4.34Å; I41-F454 HydrophobicContact CG1-CG 4.49Å; I41-F454 HydrophobicContact CG2-CB 3.76Å; I41-F454 HydrophobicContact CG2-CD1 3.68Å; I41-F454 HydrophobicContact CG2-CD2 4.25Å; I41-F454 HydrophobicContact CG2-CE1 4.35Å; I41-F454 HydrophobicContact CG2-CG 3.62Å
42I95.7Very high90.8Very high73 Ų7338.7 Ų38.737%0.37423%0.23SC..Hα-helixtrans-62.6-52.1-179.8-68.1164.9000110.4I21 F38 G39 G44 H45 F46I21-I42 HydrophobicContact CD1-CD1 3.63Å; F38-I42 VanDerWaalsContact O-CG1 3.29Å; F38-I42 WeakPolarHBondContact O-CG1 3.4Å; F38-I42 PolarHBondContact O-N 3.49Å; G39-I42 PolarHBondContact O-N 2.89Å; I42-G44 VanDerWaalsContact C-N 3.33Å; I42-G44 PolarHBondContact O-N 2.86Å; I42-H45 WeakPolarHBondContact O-CB 3.38Å; I42-H45 PolarHBondContact O-N 3.31Å; I42-F46 HydrophobicContact CG2-CD2 4.2Å; I42-F46 HydrophobicContact CG2-CE2 3.96Å; I42-F46 WeakPolarHBondContact O-CD2 3.37Å; I42-F46 PolarHBondContact O-N 3.32Å
43V96.6Very high91.1Very high12 Ų1242.6 Ų42.67%0.07325%0.247CC..Hα-helixtrans-65.6-40.1-179.9174.80000110.5I10 L13 V14 V17 G39 H45 F46 V47 L448I10-V43 HydrophobicContact CG2-CG1 4.06Å; L13-V43 HydrophobicContact CD2-CG1 4.16Å; L13-V43 HydrophobicContact CD2-CG2 4.38Å; L13-V43 HydrophobicContact CG-CG2 4.19Å; V14-V43 HydrophobicContact CG2-CB 3.75Å; V14-V43 HydrophobicContact CG2-CG1 3.72Å; V14-V43 HydrophobicContact CG2-CG2 4.2Å; V17-V43 HydrophobicContact CB-CG2 4.42Å; V17-V43 HydrophobicContact CG2-CG2 4.23Å; G39-V43 WeakPolarHBondContact O-CB 3.26Å; G39-V43 WeakPolarHBondContact O-CG2 3.35Å; G39-V43 PolarHBondContact O-N 3.11Å; V43-H45 VanDerWaalsContact C-N 3.32Å; V43-H45 PolarHBondContact O-N 3.23Å; V43-F46 PolarHBondContact O-N 2.83Å; V43-V47 HydrophobicContact CG1-CG2 3.96Å; V43-V47 WeakPolarHBondContact O-CB 3.28Å; V43-V47 VanDerWaalsContact O-CG2 3.23Å; V43-V47 WeakPolarHBondContact O-CG2 3.21Å; V43-V47 PolarHBondContact O-N 3.25Å; V43-L448 HydrophobicContact CG1-CD1 4.17Å
44G94.8Very high91.6Very high3 Ų341.9 Ų41.93%0.03124%0.244CC..Hα-helixtrans-60.2-39.4176.900000112.8G40 I41 I42 V47 S48G40-G44 WeakPolarHBondContact O-CA 3.38Å; G40-G44 PolarHBondContact O-N 2.85Å; I41-G44 PolarHBondContact O-N 3.13Å; I42-G44 VanDerWaalsContact C-N 3.33Å; I42-G44 PolarHBondContact O-N 2.86Å; G44-V47 PolarHBondContact O-N 2.9Å; G44-S48 VanDerWaalsContact O-CB 3.26Å; G44-S48 WeakPolarHBondContact O-CB 3.49Å; G44-S48 PolarHBondContact O-N 3.39Å
45H94Very high92.1Very high45 Ų4543.3 Ų43.321%0.20825%0.253CS..Hα-helixtrans-58.6-49.3173.5-176.470.6000111.7I41 I42 V43 S48 Q49 G451I41-H45 WeakPolarHBondContact O-CB 3.37Å; I41-H45 PolarHBondContact O-N 3.07Å; I42-H45 WeakPolarHBondContact O-CB 3.38Å; I42-H45 PolarHBondContact O-N 3.31Å; V43-H45 VanDerWaalsContact C-N 3.32Å; V43-H45 PolarHBondContact O-N 3.23Å; H45-S48 PolarHBondContact O-N 3.4Å; H45-Q49 PolarHBondContact CE1-NE2 3.18Å; H45-Q49 PolarHBondContact NE2-NE2 3.43Å; H45-Q49 WeakPolarHBondContact O-CG 3.06Å; H45-Q49 PolarHBondContact O-N 2.89Å; H45-G451 WeakPolarHBondContact CA-O 3.3Å; H45-G451 WeakPolarHBondContact CB-O 3.22Å
46F95.1Very high92.1Very high128 Ų12847.1 Ų47.156%0.56128%0.279SS*.Hα-helixtrans-69.5-36178.3-71-66.3000113.1I42 V43 Q49 A50I42-F46 HydrophobicContact CG2-CD2 4.2Å; I42-F46 HydrophobicContact CG2-CE2 3.96Å; I42-F46 WeakPolarHBondContact O-CD2 3.37Å; I42-F46 PolarHBondContact O-N 3.32Å; V43-F46 PolarHBondContact O-N 2.83Å; F46-Q49 PolarHBondContact O-N 3.05Å; F46-A50 VanDerWaalsContact O-CB 3.28Å; F46-A50 WeakPolarHBondContact O-CB 3.26Å; F46-A50 PolarHBondContact O-N 2.93Å
47V93.9Very high91.9Very high12 Ų1253.2 Ų53.27%0.07331%0.312CS..Hα-helixtrans-63.8-43.6175.9166.30000110.8I10 V43 G44 A50 G51 M52 L54 L448I10-V47 HydrophobicContact CD1-CG2 4.08Å; I10-V47 HydrophobicContact CG2-CG2 3.97Å; V43-V47 HydrophobicContact CG1-CG2 3.96Å; V43-V47 WeakPolarHBondContact O-CB 3.28Å; V43-V47 VanDerWaalsContact O-CG2 3.23Å; V43-V47 WeakPolarHBondContact O-CG2 3.21Å; V43-V47 PolarHBondContact O-N 3.25Å; G44-V47 PolarHBondContact O-N 2.9Å; V47-A50 PolarHBondContact O-N 3.35Å; V47-G51 PolarHBondContact O-N 2.95Å; V47-M52 HydrophobicContact CG1-CB 3.95Å; V47-M52 HydrophobicContact CG2-CE 4.18Å; V47-M52 PolarHBondContact O-N 3.34Å; V47-M52 VanDerWaalsContact O-N 3.13Å; V47-L54 HydrophobicContact CG1-CD1 4.06Å; V47-L54 HydrophobicContact CG1-CG 4.45Å; V47-L448 HydrophobicContact CG2-CD1 4.37Å
48S90.4Very high91.9Very high70 Ų7055.3 Ų55.349%0.4932%0.322SS..Hα-helixtrans-63.8-47.2175.41780000111.6G44 H45 A50 G51G44-S48 VanDerWaalsContact O-CB 3.26Å; G44-S48 WeakPolarHBondContact O-CB 3.49Å; G44-S48 PolarHBondContact O-N 3.39Å; H45-S48 PolarHBondContact O-N 3.4Å; S48-A50 VanDerWaalsContact C-N 3.28Å; S48-A50 PolarHBondContact O-N 3.05Å; S48-G51 PolarHBondContact O-N 2.7Å
49Q89.9Confident92Very high131 Ų13154.2 Ų54.261%0.61232%0.318SS*.Hα-helixtrans-61.5-35.3176.4-77.9-174.3-13.600113.4H45 F46 G51H45-Q49 PolarHBondContact CE1-NE2 3.18Å; H45-Q49 PolarHBondContact NE2-NE2 3.43Å; H45-Q49 WeakPolarHBondContact O-CG 3.06Å; H45-Q49 PolarHBondContact O-N 2.89Å; F46-Q49 PolarHBondContact O-N 3.05Å; Q49-G51 PolarHBondContact O-N 3.47Å
50A92Very high91.7Very high64 Ų6457.5 Ų57.553%0.52933%0.333SS..THydrogen-bonded Turntrans-75.3-6.1176.300000113.4F46 V47 S48 M52F46-A50 VanDerWaalsContact O-CB 3.28Å; F46-A50 WeakPolarHBondContact O-CB 3.26Å; F46-A50 PolarHBondContact O-N 2.93Å; V47-A50 PolarHBondContact O-N 3.35Å; S48-A50 VanDerWaalsContact C-N 3.28Å; S48-A50 PolarHBondContact O-N 3.05Å; A50-M52 HydrophobicContact CB-CE 3.64Å; A50-M52 HydrophobicContact CB-CG 4.19Å; A50-M52 PolarHBondContact O-N 3.44Å
51G87.7Confident91.6Very high59 Ų5962 Ų6261%0.60836%0.361SS*.THydrogen-bonded Turntrans64.925.5-176.800000113.5V47 S48 Q49 T53V47-G51 PolarHBondContact O-N 2.95Å; S48-G51 PolarHBondContact O-N 2.7Å; Q49-G51 PolarHBondContact O-N 3.47Å; G51-T53 PolarHBondContact O-N 3.41Å
52M88.6Confident91.7Very high78 Ų7863 Ų6338%0.38437%0.365SS..  trans-76.3119.4-179-80.9-170.5-90.700110.9V47 A50V47-M52 HydrophobicContact CG1-CB 3.95Å; V47-M52 HydrophobicContact CG2-CE 4.18Å; V47-M52 PolarHBondContact O-N 3.34Å; V47-M52 VanDerWaalsContact O-N 3.13Å; A50-M52 HydrophobicContact CB-CE 3.64Å; A50-M52 HydrophobicContact CB-CG 4.19Å; A50-M52 PolarHBondContact O-N 3.44Å
53T84.7Confident91.5Very high117 Ų11759.5 Ų59.572%0.71835%0.348SS*.  trans-87.7123.1174.254.50000110.6G51G51-T53 PolarHBondContact O-N 3.41Å
54L90.3Very high91.2Very high36 Ų3659.4 Ų59.419%0.18835%0.346CS..  trans-107158.6177.4-58.8177.3000110.8L6 I10 V47 S56 L59 L448L6-L54 HydrophobicContact CD2-CD2 4.02Å; L6-L54 HydrophobicContact CG-CD2 3.9Å; I10-L54 HydrophobicContact CB-CD1 4.4Å; I10-L54 HydrophobicContact CG1-CD2 4.15Å; I10-L54 HydrophobicContact CG2-CD1 4.02Å; V47-L54 HydrophobicContact CG1-CD1 4.06Å; V47-L54 HydrophobicContact CG1-CG 4.45Å; L54-S56 PolarHBondContact O-N 2.9Å; L54-S56 VanDerWaalsContact O-N 3.13Å; L54-L59 HydrophobicContact CB-CD1 4.16Å; L54-L448 HydrophobicContact CD1-CD2 3.56Å; L54-L448 HydrophobicContact CD1-CG 4.46Å
55S91.1Very high91.2Very high35 Ų3563.9 Ų63.925%0.24537%0.365CS..  trans-70.6109.5179175.20000110.9T7 D57 M58 L59T7-S55 PolarHBondContact OG1-N 3.22Å; S55-D57 PolarHBondContact O-N 3.18Å; S55-M58 PolarHBondContact O-N 2.84Å; S55-M58 WeakPolarHBondContact OG-CB 3.33Å; S55-M58 PolarHBondContact OG-N 3.2Å; S55-L59 WeakPolarHBondContact O-CG 3.49Å; S55-L59 PolarHBondContact O-N 3.48Å
56S87.1Confident91.1Very high79 Ų7961.8 Ų61.855%0.55236%0.355SS*.Hα-helixtrans-60.8-42.7179.3-169.60000112.4L54 M58 L59 H60L54-S56 PolarHBondContact O-N 2.9Å; L54-S56 VanDerWaalsContact O-N 3.13Å; S56-M58 VanDerWaalsContact C-N 3.33Å; S56-M58 PolarHBondContact O-N 3.26Å; S56-L59 PolarHBondContact O-N 3.42Å; S56-H60 WeakPolarHBondContact O-CB 3.48Å; S56-H60 PolarHBondContact O-N 3.39Å
57D89.8Confident90.9Very high129 Ų12955.7 Ų55.769%0.6933%0.329SS*.Hα-helixtrans-61.7-42.3178.1-65.3-28.2000111.6S55 H60 V61S55-D57 PolarHBondContact O-N 3.18Å; D57-H60 PolarHBondContact O-N 3.22Å; D57-V61 WeakPolarHBondContact O-CG2 3.34Å; D57-V61 PolarHBondContact O-N 3.06Å
58M92.2Very high90.9Very high45 Ų4555.8 Ų55.822%0.22233%0.329CS..Hα-helixtrans-65.3-44.7177.9-170.3175.3-148.200111.5I4 T7 V8 S55 S56 H60 V61 I62I4-M58 HydrophobicContact CB-CE 4.41Å; I4-M58 HydrophobicContact CB-SD 4.27Å; I4-M58 HydrophobicContact CG1-SD 4.44Å; I4-M58 HydrophobicContact CG2-CE 3.51Å; I4-M58 HydrophobicContact CG2-SD 4Å; T7-M58 HydrophobicContact CG2-CB 4.3Å; T7-M58 HydrophobicContact CG2-CG 4.19Å; T7-M58 HydrophobicContact CG2-SD 3.9Å; V8-M58 HydrophobicContact CG2-CE 3.45Å; V8-M58 VanDerWaalsContact CG2-CE 3.45Å; V8-M58 HydrophobicContact CG2-SD 4.09Å; S55-M58 PolarHBondContact O-N 2.84Å; S55-M58 WeakPolarHBondContact OG-CB 3.33Å; S55-M58 PolarHBondContact OG-N 3.2Å; S56-M58 VanDerWaalsContact C-N 3.33Å; S56-M58 PolarHBondContact O-N 3.26Å; M58-H60 VanDerWaalsContact C-N 3.29Å; M58-H60 PolarHBondContact O-N 3.1Å; M58-V61 PolarHBondContact O-N 3.13Å; M58-I62 HydrophobicContact CE-CD1 4.38Å; M58-I62 HydrophobicContact CG-CD1 3.8Å; M58-I62 HydrophobicContact CG-CG1 4.46Å; M58-I62 WeakPolarHBondContact O-CB 3.36Å; M58-I62 VanDerWaalsContact O-CG1 3.26Å; M58-I62 WeakPolarHBondContact O-CG1 3.28Å; M58-I62 PolarHBondContact O-N 2.94Å
59L93.4Very high91Very high13 Ų1353 Ų537%0.06831%0.308CS..Hα-helixtrans-58.1-44.7174.9-70.7175.5000110.8T7 L11 L54 S55 S56 I62 Q63 V445 L448T7-L59 HydrophobicContact CG2-CD2 3.81Å; T7-L59 HydrophobicContact CG2-CG 4.08Å; L11-L59 HydrophobicContact CD1-CD2 4.07Å; L11-L59 HydrophobicContact CD2-CD2 3.94Å; L11-L59 HydrophobicContact CG-CD2 4.2Å; L54-L59 HydrophobicContact CB-CD1 4.16Å; S55-L59 WeakPolarHBondContact O-CG 3.49Å; S55-L59 PolarHBondContact O-N 3.48Å; S56-L59 PolarHBondContact O-N 3.42Å; L59-I62 PolarHBondContact O-N 3.45Å; L59-Q63 VanDerWaalsContact O-CB 3.25Å; L59-Q63 WeakPolarHBondContact O-CB 3.4Å; L59-Q63 PolarHBondContact O-N 3.1Å; L59-V445 HydrophobicContact CB-CG1 3.89Å; L59-V445 HydrophobicContact CD2-CG1 4.23Å; L59-V445 HydrophobicContact CD2-CG2 4.04Å; L59-L448 HydrophobicContact CD1-CD2 4.42Å; L59-L448 HydrophobicContact CD2-CD2 3.88Å
60H89.6Confident91.1Very high68 Ų6847.6 Ų47.632%0.31528%0.283SS..Hα-helixtrans-63.2-48.1179-172.7-85.9000112.1S56 D57 M58 I62 Q63 E64S56-H60 WeakPolarHBondContact O-CB 3.48Å; S56-H60 PolarHBondContact O-N 3.39Å; D57-H60 PolarHBondContact O-N 3.22Å; M58-H60 VanDerWaalsContact C-N 3.29Å; M58-H60 PolarHBondContact O-N 3.1Å; H60-I62 VanDerWaalsContact C-N 3.33Å; H60-I62 PolarHBondContact O-N 3.15Å; H60-Q63 PolarHBondContact O-N 3.37Å; H60-E64 WeakPolarHBondContact O-CG 3.43Å; H60-E64 PolarHBondContact O-N 3.18Å
61V93.5Very high90.9Very high96 Ų9644.5 Ų44.558%0.58226%0.257SS*.Hα-helixtrans-59.9-44.7177.6171.10000111.2D57 M58 F65D57-V61 WeakPolarHBondContact O-CG2 3.34Å; D57-V61 PolarHBondContact O-N 3.06Å; M58-V61 PolarHBondContact O-N 3.13Å; V61-F65 WeakPolarHBondContact O-CB 3.4Å; V61-F65 PolarHBondContact O-N 2.87Å
62I95Very high91.1Very high29 Ų2941.8 Ų41.815%0.14923%0.229CC..Hα-helixtrans-64.7-41.8179.3-69.5171.4000111.1L11 M58 L59 H60 G66 L441 V445L11-I62 HydrophobicContact CD1-CD1 3.38Å; L11-I62 HydrophobicContact CD1-CG2 4.14Å; M58-I62 HydrophobicContact CE-CD1 4.38Å; M58-I62 HydrophobicContact CG-CD1 3.8Å; M58-I62 HydrophobicContact CG-CG1 4.46Å; M58-I62 WeakPolarHBondContact O-CB 3.36Å; M58-I62 VanDerWaalsContact O-CG1 3.26Å; M58-I62 WeakPolarHBondContact O-CG1 3.28Å; M58-I62 PolarHBondContact O-N 2.94Å; L59-I62 PolarHBondContact O-N 3.45Å; H60-I62 VanDerWaalsContact C-N 3.33Å; H60-I62 PolarHBondContact O-N 3.15Å; I62-G66 PolarHBondContact O-N 3.09Å; I62-L441 HydrophobicContact CG2-CB 3.88Å; I62-L441 HydrophobicContact CG2-CD2 3.9Å; I62-L441 HydrophobicContact CG2-CG 4.36Å; I62-V445 HydrophobicContact CB-CG2 4.28Å; I62-V445 HydrophobicContact CG2-CG2 3.97Å
63Q92.3Very high91.2Very high1 Ų138.1 Ų38.11%0.00521%0.211CC..Hα-helixtrans-60-54.3177.3-175.9177.9-10.300110.8L59 H60 G66 L67 F442 V445 K449L59-Q63 VanDerWaalsContact O-CB 3.25Å; L59-Q63 WeakPolarHBondContact O-CB 3.4Å; L59-Q63 PolarHBondContact O-N 3.1Å; H60-Q63 PolarHBondContact O-N 3.37Å; Q63-G66 PolarHBondContact O-N 3.47Å; Q63-L67 WeakPolarHBondContact O-CB 3.41Å; Q63-L67 PolarHBondContact O-N 2.79Å; Q63-F442 HydrophobicContact CG-CD2 3.64Å; Q63-F442 HydrophobicContact CG-CE2 3.81Å; Q63-F442 WeakPolarHBondContact O-CD2 3.48Å; Q63-V445 HydrophobicContact CB-CB 3.99Å; Q63-V445 HydrophobicContact CB-CG1 3.91Å; Q63-V445 HydrophobicContact CB-CG2 4.21Å; Q63-V445 HydrophobicContact CG-CB 4.39Å; Q63-V445 HydrophobicContact CG-CG1 4.32Å; Q63-K449 VanDerWaalsContact OE1-NZ 3.1Å
64E90.5Very high91.2Very high9 Ų932.6 Ų32.64%0.04218%0.177CC..Hα-helixtrans-67.9-41.2-177.2-63.9-54.6130.800112.2H60 L67 I68 R144 L402H60-E64 WeakPolarHBondContact O-CG 3.43Å; H60-E64 PolarHBondContact O-N 3.18Å; E64-L67 WeakPolarHBondContact O-CB 3.22Å; E64-L67 PolarHBondContact O-N 3.3Å; E64-I68 VanDerWaalsContact O-CG1 3.27Å; E64-I68 WeakPolarHBondContact O-CG1 3.46Å; E64-I68 PolarHBondContact O-N 3.49Å; E64-R144 IonicContact OE1-CZ 2.81Å; E64-R144 VanDerWaalsContact OE1-CZ 3.26Å; E64-R144 IonicContact OE1-NH1 3.24Å; E64-R144 PolarHBondContact OE1-NH1 3.45Å; E64-R144 VanDerWaalsContact OE1-NH1 3.17Å; E64-R144 IonicContact OE1-NH2 3.26Å; E64-R144 PolarHBondContact OE1-NH2 3.2Å; E64-R144 IonicContact OE2-NH2 3.83Å; E64-R144 PolarHBondContact OE2-NH2 2.7Å; E64-L402 HydrophobicContact CB-CD1 3.99Å; E64-L402 HydrophobicContact CG-CD1 4.21Å
65F93.7Very high91.1Very high98 Ų9830.9 Ų30.943%0.4317%0.168SC..Hα-helixtrans-65.1-42176.8-175.1-112.2000111.7V61 L67 I68 L69V61-F65 WeakPolarHBondContact O-CB 3.4Å; V61-F65 PolarHBondContact O-N 2.87Å; F65-L67 VanDerWaalsContact C-N 3.33Å; F65-L67 PolarHBondContact O-N 3.47Å; F65-I68 PolarHBondContact O-N 2.88Å; F65-L69 HydrophobicContact CD1-CD1 4.03Å; F65-L69 HydrophobicContact CD1-CG 4.45Å; F65-L69 HydrophobicContact CE1-CD1 3.52Å; F65-L69 HydrophobicContact CE1-CG 4.08Å; F65-L69 HydrophobicContact CE2-CD2 4.38Å; F65-L69 HydrophobicContact CE2-CG 4.38Å; F65-L69 HydrophobicContact CZ-CD1 3.87Å; F65-L69 HydrophobicContact CZ-CD2 4.07Å; F65-L69 HydrophobicContact CZ-CG 4.04Å; F65-L69 WeakPolarHBondContact O-CG 3.12Å; F65-L69 PolarHBondContact O-N 3.37Å
66G93.3Very high90.9Very high0 Ų029.7 Ų29.70%016%0.159CC..Hα-helixtrans-58.3-45.1173.400000112.1I62 Q63 L69 F70 G438I62-G66 PolarHBondContact O-N 3.09Å; Q63-G66 PolarHBondContact O-N 3.47Å; G66-L69 PolarHBondContact O-N 3.41Å; G66-F70 VanDerWaalsContact O-CB 3.27Å; G66-F70 WeakPolarHBondContact O-CB 3.22Å; G66-F70 PolarHBondContact O-N 2.91Å; G66-G438 CarbonylContact C-O 3.23Å; G66-G438 VanDerWaalsContact C-O 3.23Å; G66-G438 WeakPolarHBondContact CA-O 3.34Å; G66-G438 CarbonylContact O-C 3.56Å; G66-G438 VanDerWaalsContact O-C 3.22Å; G66-G438 WeakPolarHBondContact O-CA 3.34Å; G66-G438 VanDerWaalsContact O-O 3.14Å
67L90.8Very high90.6Very high0 Ų030.8 Ų30.80%016%0.155CC..Hα-helixtrans-60.7-46.1176.4-177.262.1000112.1Q63 E64 F65 F70 V71 A403 F442Q63-L67 WeakPolarHBondContact O-CB 3.41Å; Q63-L67 PolarHBondContact O-N 2.79Å; E64-L67 WeakPolarHBondContact O-CB 3.22Å; E64-L67 PolarHBondContact O-N 3.3Å; F65-L67 VanDerWaalsContact C-N 3.33Å; F65-L67 PolarHBondContact O-N 3.47Å; L67-F70 PolarHBondContact O-N 3.32Å; L67-V71 HydrophobicContact CD1-CG2 3.75Å; L67-V71 HydrophobicContact CG-CG2 4.31Å; L67-V71 WeakPolarHBondContact O-CB 3.44Å; L67-V71 VanDerWaalsContact O-CG2 3.3Å; L67-V71 WeakPolarHBondContact O-CG2 3.11Å; L67-V71 PolarHBondContact O-N 3.02Å; L67-A403 HydrophobicContact CD2-CB 4.12Å; L67-A403 HydrophobicContact CG-CB 4.48Å; L67-F442 HydrophobicContact CB-CD2 3.78Å; L67-F442 HydrophobicContact CB-CE2 4.22Å; L67-F442 HydrophobicContact CB-CG 4.44Å; L67-F442 HydrophobicContact CD1-CD2 4.26Å; L67-F442 HydrophobicContact CD1-CE2 4.16Å; L67-F442 HydrophobicContact CD1-CZ 4.43Å; L67-F442 HydrophobicContact CD2-CE2 4.2Å; L67-F442 HydrophobicContact CG-CD2 4.44Å; L67-F442 HydrophobicContact CG-CE2 4.44Å
68I92.8Very high89.8Confident15 Ų1525.1 Ų25.18%0.07713%0.125CC..Hα-helixtrans-59-50.5178.2-70.4162.5000110.8E64 F65 F70 V71 Y72 I378 V382 L402 P406E64-I68 VanDerWaalsContact O-CG1 3.27Å; E64-I68 WeakPolarHBondContact O-CG1 3.46Å; E64-I68 PolarHBondContact O-N 3.49Å; F65-I68 PolarHBondContact O-N 2.88Å; I68-F70 VanDerWaalsContact C-N 3.3Å; I68-F70 PolarHBondContact O-N 3.49Å; I68-V71 PolarHBondContact O-N 3.4Å; I68-Y72 WeakPolarHBondContact O-CB 3.43Å; I68-Y72 PolarHBondContact O-N 2.75Å; I68-I378 HydrophobicContact CG2-CB 4.45Å; I68-I378 HydrophobicContact CG2-CD1 4.43Å; I68-I378 HydrophobicContact CG2-CG1 4.19Å; I68-I378 HydrophobicContact CG2-CG2 3.54Å; I68-V382 HydrophobicContact CD1-CG2 4.11Å; I68-L402 HydrophobicContact CD1-CB 4.12Å; I68-L402 HydrophobicContact CD1-CD1 4.26Å; I68-L402 HydrophobicContact CD1-CD2 4.2Å; I68-L402 HydrophobicContact CD1-CG 4.41Å; I68-L402 HydrophobicContact CG1-CB 3.91Å; I68-P406 HydrophobicContact CG1-CG 4.43Å; I68-P406 HydrophobicContact CG2-CB 4.45Å; I68-P406 HydrophobicContact CG2-CG 4.28Å
69L93.8Very high89Confident12 Ų1223 Ų236%0.06312%0.115CC..Hα-helixtrans-58.7-45.3179.2-70.8-177.7000111.2F65 G66 T73 I378 L434F65-L69 HydrophobicContact CD1-CD1 4.03Å; F65-L69 HydrophobicContact CD1-CG 4.45Å; F65-L69 HydrophobicContact CE1-CD1 3.52Å; F65-L69 HydrophobicContact CE1-CG 4.08Å; F65-L69 HydrophobicContact CE2-CD2 4.38Å; F65-L69 HydrophobicContact CE2-CG 4.38Å; F65-L69 HydrophobicContact CZ-CD1 3.87Å; F65-L69 HydrophobicContact CZ-CD2 4.07Å; F65-L69 HydrophobicContact CZ-CG 4.04Å; F65-L69 WeakPolarHBondContact O-CG 3.12Å; F65-L69 PolarHBondContact O-N 3.37Å; G66-L69 PolarHBondContact O-N 3.41Å; L69-T73 WeakPolarHBondContact O-CB 3.16Å; L69-T73 WeakPolarHBondContact O-CG2 3.42Å; L69-T73 PolarHBondContact O-N 2.91Å; L69-T73 VanDerWaalsContact O-N 3.11Å; L69-T73 PolarHBondContact O-OG1 2.77Å; L69-I378 HydrophobicContact CD2-CD1 3.89Å; L69-L434 HydrophobicContact CD2-CD1 4.46Å; L69-L434 HydrophobicContact CD2-CD2 4.29Å; L69-L434 HydrophobicContact CD2-CG 4.32Å
70F90.2Very high87.9Confident16 Ų1625.8 Ų25.87%0.0713%0.134CC..Hα-helixtrans-64-46.6-179.3172.6-124.4000112.6G66 L67 I68 T73 I74 T133 P134 R435 I439G66-F70 VanDerWaalsContact O-CB 3.27Å; G66-F70 WeakPolarHBondContact O-CB 3.22Å; G66-F70 PolarHBondContact O-N 2.91Å; L67-F70 PolarHBondContact O-N 3.32Å; I68-F70 VanDerWaalsContact C-N 3.3Å; I68-F70 PolarHBondContact O-N 3.49Å; F70-T73 PolarHBondContact O-OG1 3.11Å; F70-I74 HydrophobicContact CD1-CD1 4.45Å; F70-I74 HydrophobicContact CD2-CD1 4.06Å; F70-I74 HydrophobicContact CE1-CD1 3.99Å; F70-I74 HydrophobicContact CE2-CD1 3.49Å; F70-I74 VanDerWaalsContact CE2-CD1 3.49Å; F70-I74 HydrophobicContact CE2-CG1 4.3Å; F70-I74 HydrophobicContact CG-CD1 4.48Å; F70-I74 HydrophobicContact CZ-CD1 3.44Å; F70-I74 VanDerWaalsContact CZ-CD1 3.44Å; F70-I74 WeakPolarHBondContact O-CG1 3.28Å; F70-I74 PolarHBondContact O-N 3.02Å; F70-T133 HydrophobicContact CE1-CG2 4.37Å; F70-P134 HydrophobicContact CD1-CG 4.26Å; F70-P134 HydrophobicContact CE1-CB 4.34Å; F70-P134 VanDerWaalsContact CE1-CD 3.45Å; F70-P134 HydrophobicContact CE1-CG 3.36Å; F70-P134 HydrophobicContact CZ-CG 3.81Å; F70-R435 HydrophobicContact CD2-CG 3.5Å; F70-R435 HydrophobicContact CE2-CG 3.79Å; F70-I439 HydrophobicContact CB-CB 4.44Å; F70-I439 HydrophobicContact CD1-CB 4.41Å; F70-I439 HydrophobicContact CD2-CB 3.7Å; F70-I439 HydrophobicContact CD2-CD1 4.32Å; F70-I439 HydrophobicContact CD2-CG1 4.47Å; F70-I439 HydrophobicContact CD2-CG2 4.32Å; F70-I439 HydrophobicContact CE1-CD1 4Å; F70-I439 HydrophobicContact CE1-CG1 4.49Å; F70-I439 HydrophobicContact CE2-CB 4.01Å; F70-I439 HydrophobicContact CE2-CD1 3.75Å; F70-I439 HydrophobicContact CE2-CG1 4.39Å; F70-I439 HydrophobicContact CG-CB 3.95Å; F70-I439 HydrophobicContact CZ-CB 4.48Å; F70-I439 HydrophobicContact CZ-CD1 3.59Å; F70-I439 HydrophobicContact CZ-CG1 4.41Å
71V89Confident86.6Confident0 Ų024 Ų240%013%0.133CC..Hα-helixtrans-77.4-34.3-176178.20000111.9L67 I68 I74 G75 P134 A403 L407L67-V71 HydrophobicContact CD1-CG2 3.75Å; L67-V71 HydrophobicContact CG-CG2 4.31Å; L67-V71 WeakPolarHBondContact O-CB 3.44Å; L67-V71 VanDerWaalsContact O-CG2 3.3Å; L67-V71 WeakPolarHBondContact O-CG2 3.11Å; L67-V71 PolarHBondContact O-N 3.02Å; I68-V71 PolarHBondContact O-N 3.4Å; V71-I74 WeakPolarHBondContact O-CB 3.07Å; V71-I74 PolarHBondContact O-N 3.29Å; V71-G75 PolarHBondContact O-N 2.85Å; V71-P134 HydrophobicContact CG2-CB 4.1Å; V71-A403 WeakPolarHBondContact CG1-O 3.35Å; V71-L407 HydrophobicContact CG1-CB 3.49Å; V71-L407 VanDerWaalsContact CG1-CB 3.49Å; V71-L407 HydrophobicContact CG1-CD1 3.93Å; V71-L407 HydrophobicContact CG1-CG 4.2Å
72Y92.3Very high85.4Confident2 Ų220.5 Ų20.51%0.00811%0.11CC..Hα-helixtrans-63.5-47.8174178-94.9000112I68 I74 G75 I76 P373 V374 G377 I378 A410I68-Y72 WeakPolarHBondContact O-CB 3.43Å; I68-Y72 PolarHBondContact O-N 2.75Å; Y72-I74 VanDerWaalsContact C-N 3.27Å; Y72-I74 PolarHBondContact O-N 3.14Å; Y72-G75 PolarHBondContact O-N 3.38Å; Y72-I76 HydrophobicContact CD1-CG1 4.23Å; Y72-I76 HydrophobicContact CE1-CD1 4.4Å; Y72-I76 HydrophobicContact CE1-CG1 3.65Å; Y72-I76 HydrophobicContact CE2-CD1 4.34Å; Y72-I76 HydrophobicContact CE2-CG1 4.17Å; Y72-I76 PolarHBondContact O-N 2.86Å; Y72-P373 PolarHBondContact OH-O 3.17Å; Y72-V374 HydrophobicContact CD1-CG1 4.42Å; Y72-V374 HydrophobicContact CE1-CB 4.4Å; Y72-V374 HydrophobicContact CE1-CG1 3.95Å; Y72-G377 VanDerWaalsContact CE2-C 3.41Å; Y72-I378 HydrophobicContact CD1-CD1 4.26Å; Y72-I378 HydrophobicContact CD1-CG1 3.92Å; Y72-I378 HydrophobicContact CD2-CG1 3.76Å; Y72-I378 HydrophobicContact CE1-CG1 4.32Å; Y72-I378 HydrophobicContact CE2-CG1 4.19Å; Y72-I378 HydrophobicContact CG-CD1 4.36Å; Y72-I378 HydrophobicContact CG-CG1 3.63Å; Y72-A410 HydrophobicContact CD2-CB 3.61Å; Y72-A410 HydrophobicContact CE2-CB 3.83Å; Y72-A410 HydrophobicContact CG-CB 4.23Å; Y72-A410 VanDerWaalsContact O-CB 3.29Å; Y72-A410 WeakPolarHBondContact O-CB 3.25Å
73T90.1Very high84.1Confident0 Ų023.3 Ų23.30%012%0.122CC..Hα-helixtrans-64.1-34.1178.550.60000112.3L69 F70 Q77 M426 N431 L434 R435L69-T73 WeakPolarHBondContact O-CB 3.16Å; L69-T73 WeakPolarHBondContact O-CG2 3.42Å; L69-T73 PolarHBondContact O-N 2.91Å; L69-T73 VanDerWaalsContact O-N 3.11Å; L69-T73 PolarHBondContact O-OG1 2.77Å; F70-T73 PolarHBondContact O-OG1 3.11Å; T73-Q77 WeakPolarHBondContact O-CB 3.45Å; T73-Q77 PolarHBondContact O-N 3.47Å; T73-Q77 VanDerWaalsContact O-N 3.17Å; T73-M426 HydrophobicContact CG2-SD 4.47Å; T73-N431 WeakPolarHBondContact CA-OD1 3.48Å; T73-N431 VanDerWaalsContact CB-OD1 3.29Å; T73-N431 WeakPolarHBondContact CB-OD1 3.33Å; T73-N431 PolarHBondContact O-ND2 2.86Å; T73-N431 PolarHBondContact O-OD1 3.48Å; T73-L434 HydrophobicContact CG2-CB 3.87Å; T73-L434 HydrophobicContact CG2-CD2 3.73Å; T73-L434 HydrophobicContact CG2-CG 4.03Å; T73-R435 HydrophobicContact CG2-CB 4.49Å; T73-R435 WeakPolarHBondContact OG1-CA 3.11Å; T73-R435 VanDerWaalsContact OG1-CB 3.25Å; T73-R435 WeakPolarHBondContact OG1-CB 3.33Å; T73-R435 WeakPolarHBondContact OG1-CG 3.31Å
74I84.8Confident82.6Confident1 Ų125.6 Ų25.61%0.00514%0.14CC..Hα-helixtrans-58.5-55.4166.8-81.6171.8000110.2F70 V71 Y72 I76 Q77 V78 P134 L407 M535F70-I74 HydrophobicContact CD1-CD1 4.45Å; F70-I74 HydrophobicContact CD2-CD1 4.06Å; F70-I74 HydrophobicContact CE1-CD1 3.99Å; F70-I74 HydrophobicContact CE2-CD1 3.49Å; F70-I74 VanDerWaalsContact CE2-CD1 3.49Å; F70-I74 HydrophobicContact CE2-CG1 4.3Å; F70-I74 HydrophobicContact CG-CD1 4.48Å; F70-I74 HydrophobicContact CZ-CD1 3.44Å; F70-I74 VanDerWaalsContact CZ-CD1 3.44Å; F70-I74 WeakPolarHBondContact O-CG1 3.28Å; F70-I74 PolarHBondContact O-N 3.02Å; V71-I74 WeakPolarHBondContact O-CB 3.07Å; V71-I74 PolarHBondContact O-N 3.29Å; Y72-I74 VanDerWaalsContact C-N 3.27Å; Y72-I74 PolarHBondContact O-N 3.14Å; I74-I76 VanDerWaalsContact C-N 3.34Å; I74-I76 PolarHBondContact O-N 3.23Å; I74-Q77 WeakPolarHBondContact O-CB 3.46Å; I74-Q77 PolarHBondContact O-N 3.36Å; I74-V78 HydrophobicContact CG2-CG2 4.05Å; I74-V78 WeakPolarHBondContact O-CG2 3.26Å; I74-V78 PolarHBondContact O-N 3.2Å; I74-P134 HydrophobicContact CD1-CG 3.95Å; I74-L407 HydrophobicContact CG2-CD1 3.86Å; I74-M535 HydrophobicContact CB-SD 4.35Å; I74-M535 HydrophobicContact CD1-CE 3.87Å; I74-M535 HydrophobicContact CD1-SD 4.19Å; I74-M535 HydrophobicContact CG1-CE 4.5Å; I74-M535 HydrophobicContact CG1-SD 4.37Å; I74-M535 HydrophobicContact CG2-CE 4.23Å; I74-M535 HydrophobicContact CG2-CG 4.23Å; I74-M535 HydrophobicContact CG2-SD 3.14Å; I74-M535 WeakPolarHBondContact CG2-SD 3.23Å
75G87.7Confident81.2Confident0 Ų025.6 Ų25.60%014%0.141CC..Hα-helixtrans-59.6-40.7-175.100000113.3V71 Y72 Q77 V78 G79 A410V71-G75 PolarHBondContact O-N 2.85Å; Y72-G75 PolarHBondContact O-N 3.38Å; G75-Q77 VanDerWaalsContact C-N 3.34Å; G75-Q77 PolarHBondContact O-N 3.13Å; G75-V78 PolarHBondContact O-N 3.13Å; G75-G79 WeakPolarHBondContact O-CA 3.27Å; G75-G79 PolarHBondContact O-N 2.79Å; G75-A410 CarbonylContact C-O 3.22Å; G75-A410 CarbonylContact O-C 3.59Å
76I86.4Confident79.7Confident11 Ų1124.9 Ų24.96%0.05614%0.142CC..Hα-helixtrans-63.8-42.5175.7-70.6-64.2000110.5Y72 I74 A410 L413 W424 M426Y72-I76 HydrophobicContact CD1-CG1 4.23Å; Y72-I76 HydrophobicContact CE1-CD1 4.4Å; Y72-I76 HydrophobicContact CE1-CG1 3.65Å; Y72-I76 HydrophobicContact CE2-CD1 4.34Å; Y72-I76 HydrophobicContact CE2-CG1 4.17Å; Y72-I76 PolarHBondContact O-N 2.86Å; I74-I76 VanDerWaalsContact C-N 3.34Å; I74-I76 PolarHBondContact O-N 3.23Å; I76-A410 HydrophobicContact CD1-CB 4.2Å; I76-A410 HydrophobicContact CG1-CB 3.98Å; I76-L413 HydrophobicContact CD1-CB 4.33Å; I76-W424 HydrophobicContact CD1-CB 4.35Å; I76-M426 HydrophobicContact CG2-CB 4.4Å
77Q81.8Confident78.1Confident101 Ų10133 Ų3347%0.47217%0.172SC..Hα-helixtrans-66.8-44179.4-175.7174.424.300112.7T73 I74 G75 N431T73-Q77 WeakPolarHBondContact O-CB 3.45Å; T73-Q77 PolarHBondContact O-N 3.47Å; T73-Q77 VanDerWaalsContact O-N 3.17Å; I74-Q77 WeakPolarHBondContact O-CB 3.46Å; I74-Q77 PolarHBondContact O-N 3.36Å; G75-Q77 VanDerWaalsContact C-N 3.34Å; G75-Q77 PolarHBondContact O-N 3.13Å; Q77-N431 PolarHBondContact OE1-ND2 3.39Å
78V73.1Confident76.2Confident11 Ų1139.2 Ų39.27%0.06721%0.21CC..Hα-helixtrans-86.4-15.5-176.9-72.30000113.8I74 G75 G81 F82 L411 Y531 P532I74-V78 HydrophobicContact CG2-CG2 4.05Å; I74-V78 WeakPolarHBondContact O-CG2 3.26Å; I74-V78 PolarHBondContact O-N 3.2Å; G75-V78 PolarHBondContact O-N 3.13Å; V78-G81 CarbonylContact O-C 3.56Å; V78-G81 WeakPolarHBondContact O-CA 3.28Å; V78-G81 PolarHBondContact O-N 3.3Å; V78-F82 WeakPolarHBondContact O-CB 3.33Å; V78-F82 PolarHBondContact O-N 3.45Å; V78-L411 HydrophobicContact CB-CD2 4.29Å; V78-L411 HydrophobicContact CG2-CD2 3.52Å; V78-Y531 HydrophobicContact CG1-CD1 3.73Å; V78-Y531 HydrophobicContact CG1-CE1 3.72Å; V78-P532 HydrophobicContact CB-CB 4Å; V78-P532 HydrophobicContact CB-CG 4.15Å; V78-P532 HydrophobicContact CG1-CB 4.29Å; V78-P532 HydrophobicContact CG1-CG 4.09Å
79G74.2Confident74.4Confident0 Ų044.4 Ų44.40%025%0.248CC..Hα-helixtrans-50-55.1-17700000114.8G75 G81 F82 F83 L411G75-G79 WeakPolarHBondContact O-CA 3.27Å; G75-G79 PolarHBondContact O-N 2.79Å; G79-G81 VanDerWaalsContact C-N 3.29Å; G79-G81 PolarHBondContact O-N 3.48Å; G79-F82 PolarHBondContact O-N 2.81Å; G79-F83 WeakPolarHBondContact O-CD2 3.3Å; G79-L411 WeakPolarHBondContact CA-O 3.33Å
80P70.6Confident73.2Confident72 Ų7244.2 Ų44.247%0.46825%0.248SC..Hα-helixtrans-59.1-39.5176.1-24.233.3000113.3G414P80-G414 WeakPolarHBondContact CG-O 3.37Å
81G63.9Low72.7Confident29 Ų2947.6 Ų47.630%0.29927%0.267SS..Hα-helixtrans-75.3-32.8-177.200000113.9V78 G79 F83 A84 S85V78-G81 CarbonylContact O-C 3.56Å; V78-G81 WeakPolarHBondContact O-CA 3.28Å; V78-G81 PolarHBondContact O-N 3.3Å; G79-G81 VanDerWaalsContact C-N 3.29Å; G79-G81 PolarHBondContact O-N 3.48Å; G81-F83 PolarHBondContact O-N 2.93Å; G81-A84 PolarHBondContact O-N 3.42Å; G81-S85 WeakPolarHBondContact O-CB 3.48Å; G81-S85 PolarHBondContact O-N 3.49Å
82F67.3Low72.6Confident23 Ų2354.2 Ų54.210%0.10129%0.292CS..Hα-helixtrans-59.2-49.1-177.6-177.1-87.1000112.2V78 G79 S85 L86 L411 P532 L533 F536V78-F82 WeakPolarHBondContact O-CB 3.33Å; V78-F82 PolarHBondContact O-N 3.45Å; G79-F82 PolarHBondContact O-N 2.81Å; F82-S85 PolarHBondContact O-N 2.95Å; F82-S85 PolarHBondContact O-OG 3.4Å; F82-L86 HydrophobicContact CE1-CD1 4.1Å; F82-L411 HydrophobicContact CB-CD2 4.04Å; F82-L411 HydrophobicContact CD2-CD2 4.4Å; F82-L411 HydrophobicContact CG-CD2 4.29Å; F82-P532 HydrophobicContact CB-CB 3.82Å; F82-P532 HydrophobicContact CD2-CB 3.88Å; F82-P532 WeakPolarHBondContact CD2-O 3.27Å; F82-P532 HydrophobicContact CG-CB 4.32Å; F82-L533 HydrophobicContact CE2-CB 4.47Å; F82-L533 HydrophobicContact CE2-CD1 4.04Å; F82-L533 HydrophobicContact CZ-CD1 4.1Å; F82-F536 HydrophobicContact CE2-CB 3.8Å; F82-F536 HydrophobicContact CE2-CD1 4.34Å; F82-F536 HydrophobicContact CE2-CG 4.1Å; F82-F536 HydrophobicContact CZ-CD1 4.35Å; F82-F536 HydrophobicContact CZ-CG 4.43Å
83F67.2Low72.4Confident89 Ų8955.1 Ų55.139%0.3930%0.297SS..Hα-helixtrans-77.1-27179.8-64.9-84.8000112.4G79 G81 R415G79-F83 WeakPolarHBondContact O-CD2 3.3Å; G81-F83 PolarHBondContact O-N 2.93Å; F83-R415 HydrophobicContact CD2-CB 3.75Å; F83-R415 HydrophobicContact CD2-CG 3.55Å; F83-R415 HydrophobicContact CE2-CB 3.78Å; F83-R415 HydrophobicContact CE2-CG 3.86Å; F83-R415 HydrophobicContact CG-CG 4.22Å
84A60.7Low72.4Confident48 Ų4855.3 Ų55.340%0.39730%0.298SS..Hα-helixtrans-70.2-36.317400000111.6G81 L86 R87G81-A84 PolarHBondContact O-N 3.42Å; A84-L86 VanDerWaalsContact C-N 3.29Å; A84-L86 PolarHBondContact O-N 2.83Å; A84-R87 WeakPolarHBondContact O-CB 3.39Å; A84-R87 PolarHBondContact O-N 2.95Å
85S61.4Low72.8Confident9 Ų960.4 Ų60.46%0.06332%0.324CS..Hα-helixtrans-69.3-26.6-178.273.20000113.4G81 F82 R87 N94 T529G81-S85 WeakPolarHBondContact O-CB 3.48Å; G81-S85 PolarHBondContact O-N 3.49Å; F82-S85 PolarHBondContact O-N 2.95Å; F82-S85 PolarHBondContact O-OG 3.4Å; S85-R87 PolarHBondContact O-N 2.68Å; S85-N94 PolarHBondContact O-ND2 3.2Å; S85-T529 WeakPolarHBondContact CB-O 3.34Å
86L61.8Low73.2Confident84 Ų8461.7 Ų61.744%0.4433%0.33SS..THydrogen-bonded Turntrans-70.3-5.1174.2-65.6174.2000113.7F82 A84 L533F82-L86 HydrophobicContact CE1-CD1 4.1Å; A84-L86 VanDerWaalsContact C-N 3.29Å; A84-L86 PolarHBondContact O-N 2.83Å; L86-L533 HydrophobicContact CD2-CD1 4.34Å; L86-L533 HydrophobicContact CD2-CD2 4.17Å
87R61.3Low73.6Confident169 Ų16961.2 Ų61.264%0.63833%0.327SS*.SBendtrans-78.6160.3175.3-63.2-176.2-171.8164.81.5112.2A84 S85 S89 G90 L91A84-R87 WeakPolarHBondContact O-CB 3.39Å; A84-R87 PolarHBondContact O-N 2.95Å; S85-R87 PolarHBondContact O-N 2.68Å; R87-S89 VanDerWaalsContact C-N 3.29Å; R87-S89 PolarHBondContact O-N 3.09Å; R87-G90 PolarHBondContact O-N 3.38Å; R87-L91 PolarHBondContact O-N 3.5Å
88V49.3Very low74.3Confident132 Ų13258.2 Ų58.280%0.832%0.316SS*.Hα-helixtrans-47.4-42-167.1-1750000114.5G90 L91V88-G90 VanDerWaalsContact C-N 3.27Å; V88-G90 PolarHBondContact O-N 3.3Å; V88-L91 PolarHBondContact O-N 3.12Å
89S55.3Low75.4Confident124 Ų12460.5 Ų60.587%0.86733%0.328SS*.Hα-helixtrans-66.1-25.7-178.3-490000114R87R87-S89 VanDerWaalsContact C-N 3.29Å; R87-S89 PolarHBondContact O-N 3.09Å
90G70Confident76.6Confident7 Ų760.5 Ų60.57%0.07233%0.328CS..Hα-helixtrans-97.2-12178.300000114.2R87 V88 R92 L93 N94R87-G90 PolarHBondContact O-N 3.38Å; V88-G90 VanDerWaalsContact C-N 3.27Å; V88-G90 PolarHBondContact O-N 3.3Å; G90-R92 VanDerWaalsContact C-N 3.32Å; G90-R92 PolarHBondContact O-N 3.47Å; G90-L93 PolarHBondContact O-N 3Å; G90-L93 VanDerWaalsContact O-N 3.14Å; G90-N94 WeakPolarHBondContact O-CB 3.24Å; G90-N94 PolarHBondContact O-N 3.34Å; G90-N94 PolarHBondContact O-ND2 3.1Å
91L79.7Confident77.8Confident88 Ų8857.4 Ų57.446%0.46131%0.307SS..Hα-helixtrans-58.5-42.6-170.3-17564.4000112.5R87 V88 L93 N94 L95R87-L91 PolarHBondContact O-N 3.5Å; V88-L91 PolarHBondContact O-N 3.12Å; L91-L93 PolarHBondContact O-N 2.89Å; L91-N94 PolarHBondContact O-N 3.08Å; L91-L95 HydrophobicContact CG-CD1 4.14Å; L91-L95 WeakPolarHBondContact O-CB 3.44Å; L91-L95 WeakPolarHBondContact O-CG 3.41Å; L91-L95 PolarHBondContact O-N 3.33Å
92R86.3Confident79.4Confident138 Ų13860.4 Ų60.452%0.52132%0.315SS..Hα-helixtrans-63.2-43.5179.5-164.7-177.9-159.117611.5112.2G90 L95 F96 A489G90-R92 VanDerWaalsContact C-N 3.32Å; G90-R92 PolarHBondContact O-N 3.47Å; R92-L95 PolarHBondContact O-N 3.15Å; R92-F96 HydrophobicContact CG-CD2 4.46Å; R92-F96 HydrophobicContact CG-CE2 4.13Å; R92-F96 VanDerWaalsContact O-CD2 3.25Å; R92-F96 WeakPolarHBondContact O-CD2 3.18Å; R92-F96 PolarHBondContact O-N 3.37Å; R92-A489 PolarHBondContact NH1-O 2.82Å; R92-A489 PolarHBondContact NH2-O 2.92Å
93L88.4Confident80.9Confident22 Ų2260.7 Ų60.712%0.11532%0.318CS..Hα-helixtrans-66.3-43.1178-69.4170.7000110.8G90 L91 L95 F96 A97 M491 T495 M499 T529 V530G90-L93 PolarHBondContact O-N 3Å; G90-L93 VanDerWaalsContact O-N 3.14Å; L91-L93 PolarHBondContact O-N 2.89Å; L93-L95 PolarHBondContact O-N 3.36Å; L93-F96 PolarHBondContact O-N 3.27Å; L93-A97 WeakPolarHBondContact O-CB 3.29Å; L93-A97 PolarHBondContact O-N 3.36Å; L93-M491 HydrophobicContact CD2-CE 3.61Å; L93-M491 HydrophobicContact CD2-SD 3.62Å; L93-T495 HydrophobicContact CD1-CG2 4.46Å; L93-T495 HydrophobicContact CD2-CG2 3.59Å; L93-M499 HydrophobicContact CD2-CB 4.27Å; L93-M499 HydrophobicContact CD2-CG 4.4Å; L93-T529 HydrophobicContact CB-CG2 4.33Å; L93-T529 HydrophobicContact CD1-CG2 4.06Å; L93-V530 HydrophobicContact CB-CG1 3.66Å
94N89.6Confident82.3Confident4 Ų456.5 Ų56.52%0.02130%0.299CS..Hα-helixtrans-63.3-39.1177.4-82.6-42.1000112.5S85 G90 L91 F96 A97 V98 V530 L533S85-N94 PolarHBondContact O-ND2 3.2Å; G90-N94 WeakPolarHBondContact O-CB 3.24Å; G90-N94 PolarHBondContact O-N 3.34Å; G90-N94 PolarHBondContact O-ND2 3.1Å; L91-N94 PolarHBondContact O-N 3.08Å; N94-F96 PolarHBondContact O-N 3.15Å; N94-A97 PolarHBondContact O-N 2.91Å; N94-V98 WeakPolarHBondContact O-CB 3.3Å; N94-V98 WeakPolarHBondContact O-CG2 3.33Å; N94-V98 PolarHBondContact O-N 3Å; N94-V530 WeakPolarHBondContact OD1-CA 3.48Å; N94-L533 HydrophobicContact CB-CD2 3.79Å
95L93.8Very high84Confident108 Ų10854.6 Ų54.657%0.56529%0.285SS*.Hα-helixtrans-59.6-46.2176.2-79.8164.3000112.3L91 R92 L93 V98 L99L91-L95 HydrophobicContact CG-CD1 4.14Å; L91-L95 WeakPolarHBondContact O-CB 3.44Å; L91-L95 WeakPolarHBondContact O-CG 3.41Å; L91-L95 PolarHBondContact O-N 3.33Å; R92-L95 PolarHBondContact O-N 3.15Å; L93-L95 PolarHBondContact O-N 3.36Å; L95-V98 PolarHBondContact O-N 3.46Å; L95-L99 WeakPolarHBondContact O-CB 3.24Å; L95-L99 PolarHBondContact O-N 3.3Å
96F95.7Very high85.7Confident27 Ų2758.9 Ų58.912%0.11831%0.307CS..Hα-helixtrans-66.2-39.8175.6-74.3-65000112R92 L93 N94 L99 I100 V481 L484 A485 A489 M491 M499R92-F96 HydrophobicContact CG-CD2 4.46Å; R92-F96 HydrophobicContact CG-CE2 4.13Å; R92-F96 VanDerWaalsContact O-CD2 3.25Å; R92-F96 WeakPolarHBondContact O-CD2 3.18Å; R92-F96 PolarHBondContact O-N 3.37Å; L93-F96 PolarHBondContact O-N 3.27Å; N94-F96 PolarHBondContact O-N 3.15Å; F96-L99 WeakPolarHBondContact O-CB 3.41Å; F96-L99 PolarHBondContact O-N 3.02Å; F96-I100 WeakPolarHBondContact O-CG1 3.45Å; F96-I100 PolarHBondContact O-N 3.5Å; F96-V481 HydrophobicContact CB-CG1 3.92Å; F96-V481 HydrophobicContact CD1-CG1 3.77Å; F96-V481 HydrophobicContact CG-CG1 4.28Å; F96-L484 HydrophobicContact CE1-CB 4.42Å; F96-A485 HydrophobicContact CD1-CB 4.08Å; F96-A485 HydrophobicContact CD2-CB 4.29Å; F96-A485 HydrophobicContact CE1-CB 4.07Å; F96-A485 HydrophobicContact CE2-CB 4.29Å; F96-A485 HydrophobicContact CG-CB 4.19Å; F96-A485 HydrophobicContact CZ-CB 4.18Å; F96-A489 HydrophobicContact CE2-CB 3.57Å; F96-A489 HydrophobicContact CZ-CB 3.66Å; F96-M491 HydrophobicContact CD2-CE 3.63Å; F96-M491 HydrophobicContact CE2-CE 3.85Å; F96-M499 HydrophobicContact CB-CE 3.99Å; F96-M499 HydrophobicContact CB-SD 4.22Å
97A95.2Very high87.3Confident0 Ų055.9 Ų55.90%029%0.291CS..Hα-helixtrans-66.5-39.3178.400000112.5L93 N94 L99 I100 V101 M499 V530 V534L93-A97 WeakPolarHBondContact O-CB 3.29Å; L93-A97 PolarHBondContact O-N 3.36Å; N94-A97 PolarHBondContact O-N 2.91Å; A97-L99 VanDerWaalsContact C-N 3.33Å; A97-I100 WeakPolarHBondContact O-CB 3.22Å; A97-I100 PolarHBondContact O-N 2.91Å; A97-V101 PolarHBondContact O-N 2.76Å; A97-M499 HydrophobicContact CB-CG 4.47Å; A97-V530 HydrophobicContact CB-CB 3.67Å; A97-V530 HydrophobicContact CB-CG1 3.82Å; A97-V530 HydrophobicContact CB-CG2 4.24Å; A97-V534 HydrophobicContact CB-CG2 3.51Å
98V95.6Very high89.1Confident39 Ų3947.8 Ų47.824%0.23626%0.261CS..Hα-helixtrans-61.5-43.3171.41700000110.4N94 L95 I100 V101 I102 L533 L537N94-V98 WeakPolarHBondContact O-CB 3.3Å; N94-V98 WeakPolarHBondContact O-CG2 3.33Å; N94-V98 PolarHBondContact O-N 3Å; L95-V98 PolarHBondContact O-N 3.46Å; V98-I100 VanDerWaalsContact C-N 3.28Å; V98-I100 PolarHBondContact O-N 3.04Å; V98-V101 PolarHBondContact O-N 2.93Å; V98-V101 VanDerWaalsContact O-N 3.09Å; V98-I102 HydrophobicContact CG1-CD1 3.74Å; V98-I102 HydrophobicContact CG1-CG1 4.29Å; V98-I102 WeakPolarHBondContact O-CG1 3.35Å; V98-I102 PolarHBondContact O-N 3.03Å; V98-L533 HydrophobicContact CG2-CD2 3.69Å; V98-L533 HydrophobicContact CG2-CG 4.33Å; V98-L537 HydrophobicContact CB-CD1 4.45Å; V98-L537 HydrophobicContact CG1-CD1 4.44Å; V98-L537 HydrophobicContact CG2-CD1 3.7Å
99L97.2Very high91.3Very high59 Ų5942.6 Ų42.631%0.30923%0.232SC..Hα-helixtrans-59.7-38.6176.6-175.962.4000111.9L95 F96 A97 I102 I103 V481 L484L95-L99 WeakPolarHBondContact O-CB 3.24Å; L95-L99 PolarHBondContact O-N 3.3Å; F96-L99 WeakPolarHBondContact O-CB 3.41Å; F96-L99 PolarHBondContact O-N 3.02Å; A97-L99 VanDerWaalsContact C-N 3.33Å; L99-I102 PolarHBondContact O-N 3.35Å; L99-I103 HydrophobicContact CD1-CD1 3.93Å; L99-I103 HydrophobicContact CD1-CG1 4.13Å; L99-I103 HydrophobicContact CD2-CD1 4.49Å; L99-I103 HydrophobicContact CG-CD1 3.82Å; L99-I103 HydrophobicContact CG-CG1 4.39Å; L99-I103 WeakPolarHBondContact O-CB 3.37Å; L99-I103 VanDerWaalsContact O-CG1 3.28Å; L99-I103 WeakPolarHBondContact O-CG1 3.32Å; L99-I103 PolarHBondContact O-N 3.26Å; L99-V481 HydrophobicContact CB-CG2 4.3Å; L99-V481 HydrophobicContact CD2-CG2 3.9Å; L99-V481 HydrophobicContact CG-CG2 3.8Å; L99-L484 HydrophobicContact CD2-CD1 4.3Å
100I97.6Very high93.2Very high0 Ų041.6 Ų41.60%022%0.216CC..Hα-helixtrans-61-44.5173.8-68.7169000111F96 A97 V98 G104 P477 L478 V481 M499 L500 S503 M504F96-I100 WeakPolarHBondContact O-CG1 3.45Å; F96-I100 PolarHBondContact O-N 3.5Å; A97-I100 WeakPolarHBondContact O-CB 3.22Å; A97-I100 PolarHBondContact O-N 2.91Å; V98-I100 VanDerWaalsContact C-N 3.28Å; V98-I100 PolarHBondContact O-N 3.04Å; I100-G104 PolarHBondContact O-N 3.16Å; I100-P477 HydrophobicContact CG2-CB 4.03Å; I100-L478 HydrophobicContact CD1-CD2 4.41Å; I100-L478 HydrophobicContact CG2-CD2 4.44Å; I100-V481 HydrophobicContact CD1-CB 4.06Å; I100-V481 HydrophobicContact CD1-CG1 3.92Å; I100-V481 HydrophobicContact CG1-CB 3.5Å; I100-V481 VanDerWaalsContact CG1-CB 3.5Å; I100-V481 HydrophobicContact CG1-CG1 3.64Å; I100-V481 HydrophobicContact CG1-CG2 3.6Å; I100-M499 HydrophobicContact CD1-CE 4.45Å; I100-M499 HydrophobicContact CD1-SD 3.6Å; I100-L500 HydrophobicContact CD1-CD2 3.6Å; I100-S503 VanDerWaalsContact CD1-OG 3.24Å; I100-S503 WeakPolarHBondContact CD1-OG 3.3Å; I100-M504 HydrophobicContact CG2-CE 3.84Å
101V97Very high94.5Very high6 Ų641.9 Ų41.94%0.03622%0.215CC..Hα-helixtrans-63.9-44.9178.51790000111A97 V98 G104 G105 V534 L537 R538A97-V101 PolarHBondContact O-N 2.76Å; V98-V101 PolarHBondContact O-N 2.93Å; V98-V101 VanDerWaalsContact O-N 3.09Å; V101-G104 PolarHBondContact O-N 2.91Å; V101-G105 PolarHBondContact O-N 3.09Å; V101-V534 HydrophobicContact CG2-CB 4.49Å; V101-V534 HydrophobicContact CG2-CG1 3.86Å; V101-V534 HydrophobicContact CG2-CG2 4.47Å; V101-L537 HydrophobicContact CG1-CB 4.02Å; V101-R538 HydrophobicContact CG1-CG 4.31Å; V101-R538 HydrophobicContact CG2-CG 4.01Å
102I97.3Very high95.2Very high92 Ų9239.2 Ų39.247%0.47220%0.2SC..Hα-helixtrans-61.9-50.3178.9-67.6170.8000110.7V98 L99 G104 G105 L106V98-I102 HydrophobicContact CG1-CD1 3.74Å; V98-I102 HydrophobicContact CG1-CG1 4.29Å; V98-I102 WeakPolarHBondContact O-CG1 3.35Å; V98-I102 PolarHBondContact O-N 3.03Å; L99-I102 PolarHBondContact O-N 3.35Å; I102-G104 VanDerWaalsContact C-N 3.29Å; I102-G104 PolarHBondContact O-N 3.24Å; I102-G105 PolarHBondContact O-N 3.19Å; I102-L106 HydrophobicContact CG2-CD1 3.91Å; I102-L106 HydrophobicContact CG2-CG 4.39Å; I102-L106 WeakPolarHBondContact O-CG 3.43Å; I102-L106 PolarHBondContact O-N 3.41Å
103I97.7Very high95.6Very high30 Ų3038.6 Ų38.615%0.15420%0.202CC..Hα-helixtrans-63.1-39.4178.9-63.3170.8000110.1L99 G105 L106 V107 V476 P477 T480 V481L99-I103 HydrophobicContact CD1-CD1 3.93Å; L99-I103 HydrophobicContact CD1-CG1 4.13Å; L99-I103 HydrophobicContact CD2-CD1 4.49Å; L99-I103 HydrophobicContact CG-CD1 3.82Å; L99-I103 HydrophobicContact CG-CG1 4.39Å; L99-I103 WeakPolarHBondContact O-CB 3.37Å; L99-I103 VanDerWaalsContact O-CG1 3.28Å; L99-I103 WeakPolarHBondContact O-CG1 3.32Å; L99-I103 PolarHBondContact O-N 3.26Å; I103-G105 PolarHBondContact O-N 3.23Å; I103-L106 PolarHBondContact O-N 3.31Å; I103-V107 HydrophobicContact CG2-CG2 4.08Å; I103-V107 WeakPolarHBondContact O-CB 3.26Å; I103-V107 VanDerWaalsContact O-CG2 3.26Å; I103-V107 WeakPolarHBondContact O-CG2 3.32Å; I103-V107 PolarHBondContact O-N 3.1Å; I103-V476 HydrophobicContact CG2-CG1 4.41Å; I103-P477 HydrophobicContact CB-CB 4.13Å; I103-P477 HydrophobicContact CB-CG 4.39Å; I103-P477 HydrophobicContact CG2-CB 4.02Å; I103-P477 HydrophobicContact CG2-CG 3.98Å; I103-T480 HydrophobicContact CD1-CG2 4.42Å; I103-V481 HydrophobicContact CD1-CG2 3.71Å
104G97Very high95.9Very high0 Ų043.2 Ų43.20%023%0.226CC..Hα-helixtrans-59.4-45.217500000112.8I100 V101 I102 T108I100-G104 PolarHBondContact O-N 3.16Å; V101-G104 PolarHBondContact O-N 2.91Å; I102-G104 VanDerWaalsContact C-N 3.29Å; I102-G104 PolarHBondContact O-N 3.24Å; G104-T108 WeakPolarHBondContact O-CB 3.16Å; G104-T108 PolarHBondContact O-N 3.38Å; G104-T108 PolarHBondContact O-OG1 2.91Å
105G96.3Very high96.1Very high9 Ų947.9 Ų47.99%0.09325%0.246CC..Hα-helixtrans-63.5-41.1174.300000112.8V101 I102 I103 T108 A109V101-G105 PolarHBondContact O-N 3.09Å; I102-G105 PolarHBondContact O-N 3.19Å; I103-G105 PolarHBondContact O-N 3.23Å; G105-T108 WeakPolarHBondContact O-CB 3.41Å; G105-T108 PolarHBondContact O-N 3.18Å; G105-A109 WeakPolarHBondContact O-CB 3.34Å; G105-A109 PolarHBondContact O-N 2.92Å
106L96.9Very high96Very high99 Ų9949.4 Ų49.452%0.51826%0.255SS..Hα-helixtrans-66.3-45177.1-72.9172.1000112.7I102 I103 T108 A109 I110I102-L106 HydrophobicContact CG2-CD1 3.91Å; I102-L106 HydrophobicContact CG2-CG 4.39Å; I102-L106 WeakPolarHBondContact O-CG 3.43Å; I102-L106 PolarHBondContact O-N 3.41Å; I103-L106 PolarHBondContact O-N 3.31Å; L106-T108 VanDerWaalsContact C-N 3.27Å; L106-T108 PolarHBondContact O-N 3.11Å; L106-A109 WeakPolarHBondContact O-CB 3.46Å; L106-A109 PolarHBondContact O-N 2.79Å; L106-I110 VanDerWaalsContact O-CG1 3.27Å; L106-I110 WeakPolarHBondContact O-CG1 3.18Å; L106-I110 PolarHBondContact O-N 3.42Å
107V97.2Very high95.9Very high20 Ų2048.3 Ų48.312%0.12125%0.25CS..Hα-helixtrans-59.9-43.5175.6172.40000109.7I103 A109 I110 L111 I473 V476I103-V107 HydrophobicContact CG2-CG2 4.08Å; I103-V107 WeakPolarHBondContact O-CB 3.26Å; I103-V107 VanDerWaalsContact O-CG2 3.26Å; I103-V107 WeakPolarHBondContact O-CG2 3.32Å; I103-V107 PolarHBondContact O-N 3.1Å; V107-A109 PolarHBondContact O-N 3.45Å; V107-I110 PolarHBondContact O-N 3.45Å; V107-L111 HydrophobicContact CG1-CD1 3.93Å; V107-L111 HydrophobicContact CG1-CG 4.34Å; V107-L111 WeakPolarHBondContact O-CB 3.42Å; V107-L111 VanDerWaalsContact O-CG 3.27Å; V107-L111 WeakPolarHBondContact O-CG 3.06Å; V107-L111 PolarHBondContact O-N 2.97Å; V107-I473 HydrophobicContact CG1-CG1 3.95Å; V107-V476 HydrophobicContact CG2-CB 4.1Å; V107-V476 HydrophobicContact CG2-CG1 3.75Å
108T97.2Very high95.8Very high0 Ų051.1 Ų51.10%027%0.268CS..Hα-helixtrans-59.2-46.4175.3-55.30000111.6G104 G105 L106 I110 L111 H112 V122 F126 I473 L545G104-T108 WeakPolarHBondContact O-CB 3.16Å; G104-T108 PolarHBondContact O-N 3.38Å; G104-T108 PolarHBondContact O-OG1 2.91Å; G105-T108 WeakPolarHBondContact O-CB 3.41Å; G105-T108 PolarHBondContact O-N 3.18Å; L106-T108 VanDerWaalsContact C-N 3.27Å; L106-T108 PolarHBondContact O-N 3.11Å; T108-I110 PolarHBondContact O-N 3.12Å; T108-L111 PolarHBondContact O-N 3.08Å; T108-H112 WeakPolarHBondContact O-CB 3.22Å; T108-H112 PolarHBondContact O-N 3.35Å; T108-V122 HydrophobicContact CG2-CG2 3.74Å; T108-F126 HydrophobicContact CG2-CB 3.81Å; T108-F126 HydrophobicContact CG2-CD2 4.37Å; T108-F126 HydrophobicContact CG2-CG 4.34Å; T108-F126 VanDerWaalsContact OG1-CD2 3.22Å; T108-F126 WeakPolarHBondContact OG1-CD2 3.35Å; T108-I473 HydrophobicContact CG2-CD1 4.33Å; T108-L545 HydrophobicContact CG2-CD1 3.98Å
109A95.8Very high95.7Very high22 Ų2250.3 Ų50.318%0.18226%0.263CS..Hα-helixtrans-60.7-42.3177.400000112.9G105 L106 V107 K113 F549G105-A109 WeakPolarHBondContact O-CB 3.34Å; G105-A109 PolarHBondContact O-N 2.92Å; L106-A109 WeakPolarHBondContact O-CB 3.46Å; L106-A109 PolarHBondContact O-N 2.79Å; V107-A109 PolarHBondContact O-N 3.45Å; A109-K113 PolarHBondContact O-N 2.88Å; A109-F549 HydrophobicContact CB-CE1 4.46Å; A109-F549 HydrophobicContact CB-CE2 4.36Å; A109-F549 HydrophobicContact CB-CZ 3.56Å
110I96.3Very high95.5Very high104 Ų10448 Ų4853%0.53325%0.251SS..Hα-helixtrans-65.9-46.5177.8-68.7164.3000110L106 V107 T108 H112 K113 L114L106-I110 VanDerWaalsContact O-CG1 3.27Å; L106-I110 WeakPolarHBondContact O-CG1 3.18Å; L106-I110 PolarHBondContact O-N 3.42Å; V107-I110 PolarHBondContact O-N 3.45Å; T108-I110 PolarHBondContact O-N 3.12Å; I110-H112 PolarHBondContact O-N 3Å; I110-K113 PolarHBondContact O-N 3.49Å; I110-L114 WeakPolarHBondContact O-CB 3.47Å; I110-L114 PolarHBondContact O-N 3.22Å
111L96.3Very high95.4Very high12 Ų1248 Ų486%0.06325%0.251CS..Hα-helixtrans-62.6-42.3179-69.3174000111.8V107 T108 K113 L114 F115 I117 Y469 L472 I473V107-L111 HydrophobicContact CG1-CD1 3.93Å; V107-L111 HydrophobicContact CG1-CG 4.34Å; V107-L111 WeakPolarHBondContact O-CB 3.42Å; V107-L111 VanDerWaalsContact O-CG 3.27Å; V107-L111 WeakPolarHBondContact O-CG 3.06Å; V107-L111 PolarHBondContact O-N 2.97Å; T108-L111 PolarHBondContact O-N 3.08Å; L111-K113 VanDerWaalsContact C-N 3.35Å; L111-K113 PolarHBondContact O-N 3.49Å; L111-L114 PolarHBondContact O-N 3.32Å; L111-F115 HydrophobicContact CD2-CD2 3.81Å; L111-F115 HydrophobicContact CD2-CE2 3.59Å; L111-F115 PolarHBondContact O-N 2.82Å; L111-F115 VanDerWaalsContact O-N 3.11Å; L111-I117 HydrophobicContact CB-CD1 4.1Å; L111-I117 WeakPolarHBondContact O-CD1 3.21Å; L111-Y469 HydrophobicContact CD1-CD1 4.45Å; L111-Y469 HydrophobicContact CD2-CD1 4Å; L111-Y469 HydrophobicContact CD2-CE1 4.48Å; L111-L472 HydrophobicContact CD1-CB 4.32Å; L111-L472 HydrophobicContact CD2-CD1 4.08Å; L111-I473 HydrophobicContact CD1-CD1 3.99Å; L111-I473 HydrophobicContact CD1-CG1 3.73Å
112H95.4Very high95.4Very high32 Ų3247.8 Ų47.815%0.14825%0.25CC..Hα-helixtrans-54.3-49.817517550000111.8T108 I110 D116 I117 V122 F549T108-H112 WeakPolarHBondContact O-CB 3.22Å; T108-H112 PolarHBondContact O-N 3.35Å; I110-H112 PolarHBondContact O-N 3Å; H112-D116 VanDerWaalsContact O-CA 3.29Å; H112-D116 WeakPolarHBondContact O-CA 3.4Å; H112-D116 PolarHBondContact O-N 3.13Å; H112-D116 VanDerWaalsContact O-N 3.14Å; H112-I117 PolarHBondContact CE1-O 3.04Å; H112-I117 PolarHBondContact ND1-O 3.21Å; H112-I117 PolarHBondContact O-N 3.35Å; H112-V122 HydrophobicContact CB-CB 4.44Å; H112-V122 HydrophobicContact CB-CG1 4.09Å; H112-V122 HydrophobicContact CB-CG2 4.05Å; H112-F549 HydrophobicContact CB-CE2 4.47Å; H112-F549 AromaticContact CD2-CD1 3.68Å; H112-F549 AromaticContact CD2-CD2 3.48Å; H112-F549 VanDerWaalsContact CD2-CD2 3.48Å; H112-F549 WeakPolarHBondContact CD2-CD2 3.32Å; H112-F549 AromaticContact CD2-CE1 3.95Å; H112-F549 AromaticContact CD2-CE2 3.73Å; H112-F549 AromaticContact CD2-CG 3.48Å; H112-F549 VanDerWaalsContact CD2-CG 3.48Å; H112-F549 WeakPolarHBondContact CD2-CG 3.38Å; H112-F549 AromaticContact CD2-CZ 3.98Å; H112-F549 AromaticContact NE2-CD2 3.92Å; H112-F549 AromaticContact NE2-CG 3.62Å
113K93.2Very high95.3Very high126 Ų12643.4 Ų43.455%0.54823%0.227SC..Hα-helixtrans-77.8-32-177.1-73.8-157.7173.6-1640114.6A109 I110 L111A109-K113 PolarHBondContact O-N 2.88Å; I110-K113 PolarHBondContact O-N 3.49Å; L111-K113 VanDerWaalsContact C-N 3.35Å; L111-K113 PolarHBondContact O-N 3.49Å
114L94.8Very high95.3Very high118 Ų11842 Ų4262%0.61822%0.22SC*.Hα-helixtrans-82.9-29.5-173.6-168.7126.5000112.3I110 L111I110-L114 WeakPolarHBondContact O-CB 3.47Å; I110-L114 PolarHBondContact O-N 3.22Å; L111-L114 PolarHBondContact O-N 3.32Å
115F94.7Very high95.3Very high103 Ų10342 Ų4245%0.45222%0.22SC..THydrogen-bonded Turntrans-114.59.9-179.1-63-75000113.1L111 I117 Y469L111-F115 HydrophobicContact CD2-CD2 3.81Å; L111-F115 HydrophobicContact CD2-CE2 3.59Å; L111-F115 PolarHBondContact O-N 2.82Å; L111-F115 VanDerWaalsContact O-N 3.11Å; F115-I117 HydrophobicContact CB-CD1 4.19Å; F115-I117 HydrophobicContact CB-CG1 3.82Å; F115-I117 PolarHBondContact O-N 3.4Å; F115-I117 VanDerWaalsContact O-N 3.13Å; F115-Y469 HydrophobicContact CD1-CE1 4.36Å; F115-Y469 WeakPolarHBondContact CD1-OH 3.32Å; F115-Y469 HydrophobicContact CD2-CD1 4.41Å; F115-Y469 AromaticContact CD2-CE1 3.64Å; F115-Y469 HydrophobicContact CD2-CE1 3.64Å; F115-Y469 AromaticContact CD2-CZ 4Å; F115-Y469 HydrophobicContact CE1-CE1 4.49Å; F115-Y469 AromaticContact CE2-CE1 3.8Å; F115-Y469 HydrophobicContact CE2-CE1 3.8Å; F115-Y469 AromaticContact CG-CE1 3.94Å; F115-Y469 HydrophobicContact CG-CE1 3.94Å; F115-Y469 AromaticContact CG-CZ 3.84Å; F115-Y469 WeakPolarHBondContact CG-OH 3.31Å; F115-Y469 HydrophobicContact CZ-CE1 4.23Å
116D91.6Very high95.3Very high140 Ų14041.6 Ų41.675%0.74922%0.216SC*.THydrogen-bonded Turntrans47.540.9-179.1-67.9-42.5000113.7H112H112-D116 VanDerWaalsContact O-CA 3.29Å; H112-D116 WeakPolarHBondContact O-CA 3.4Å; H112-D116 PolarHBondContact O-N 3.13Å; H112-D116 VanDerWaalsContact O-N 3.14Å
117I93.7Very high95.2Very high4 Ų436.9 Ų36.92%0.02119%0.191CC..  trans-70.5129.2-176.5-52.7169.5000108.4L111 H112 F115 L119 V121 V122 I125 Y469L111-I117 HydrophobicContact CB-CD1 4.1Å; L111-I117 WeakPolarHBondContact O-CD1 3.21Å; H112-I117 PolarHBondContact CE1-O 3.04Å; H112-I117 PolarHBondContact ND1-O 3.21Å; H112-I117 PolarHBondContact O-N 3.35Å; F115-I117 HydrophobicContact CB-CD1 4.19Å; F115-I117 HydrophobicContact CB-CG1 3.82Å; F115-I117 PolarHBondContact O-N 3.4Å; F115-I117 VanDerWaalsContact O-N 3.13Å; I117-L119 PolarHBondContact O-N 3.01Å; I117-V121 HydrophobicContact CG2-CB 4.01Å; I117-V121 HydrophobicContact CG2-CG1 3.69Å; I117-V122 HydrophobicContact CB-CB 4.22Å; I117-V122 HydrophobicContact CD1-CG2 4.35Å; I117-V122 HydrophobicContact CG2-CB 3.89Å; I117-V122 HydrophobicContact CG2-CG2 4.44Å; I117-I125 HydrophobicContact CG2-CD1 4.42Å; I117-Y469 HydrophobicContact CD1-CD2 3.39Å; I117-Y469 HydrophobicContact CD1-CE2 3.45Å; I117-Y469 VanDerWaalsContact CD1-CE2 3.45Å; I117-Y469 HydrophobicContact CD1-CG 3.97Å; I117-Y469 HydrophobicContact CG1-CD2 4.27Å; I117-Y469 HydrophobicContact CG1-CE2 3.9Å
118P93Very high95.1Very high59 Ų5935.9 Ų35.938%0.38319%0.185SC..  trans-52.9141.7178-27.334.3000112.9V121 V122P118-V121 HydrophobicContact CB-CB 4.25Å; P118-V121 HydrophobicContact CB-CG2 4.01Å; P118-V121 HydrophobicContact CG-CG2 4.32Å; P118-V121 WeakPolarHBondContact O-CB 3.33Å; P118-V121 PolarHBondContact O-N 2.9Å; P118-V122 PolarHBondContact O-N 3.28Å
119L93.1Very high95Very high22 Ų2236 Ų3612%0.11519%0.186CC..Hα-helixtrans-56.1-46.4-174.6-177.463.6000113.4I117 V121 V122 L123 L143 F549 W550I117-L119 PolarHBondContact O-N 3.01Å; L119-V121 VanDerWaalsContact C-N 3.28Å; L119-V121 PolarHBondContact O-N 3.38Å; L119-V122 HydrophobicContact CD1-CG1 4.31Å; L119-V122 WeakPolarHBondContact O-CG1 3.46Å; L119-V122 PolarHBondContact O-N 2.97Å; L119-L123 HydrophobicContact CD1-CD1 4.02Å; L119-L123 HydrophobicContact CD1-CD2 4.49Å; L119-L123 HydrophobicContact CD1-CG 4.09Å; L119-L123 HydrophobicContact CG-CD1 4.03Å; L119-L123 HydrophobicContact CG-CG 4.5Å; L119-L123 VanDerWaalsContact O-CG 3.22Å; L119-L123 WeakPolarHBondContact O-CG 3.4Å; L119-L123 PolarHBondContact O-N 3.46Å; L119-L143 HydrophobicContact CD2-CD2 4.01Å; L119-L143 HydrophobicContact CG-CD2 4.19Å; L119-F549 HydrophobicContact CD1-CB 3.86Å; L119-F549 HydrophobicContact CD1-CD2 3.8Å; L119-F549 HydrophobicContact CD1-CG 4.32Å; L119-W550 HydrophobicContact CD2-CE3 4.23Å
120P94.5Very high94.9Very high11 Ų1134.9 Ų34.97%0.07118%0.177CC..Hα-helixtrans-61.2-38.6176.7-23.535.8000112.7G124 L143 T148 M152 M156P120-G124 PolarHBondContact O-N 3.3Å; P120-G124 VanDerWaalsContact O-N 3.11Å; P120-L143 HydrophobicContact CB-CD1 3.87Å; P120-L143 HydrophobicContact CG-CD1 4.11Å; P120-T148 HydrophobicContact CG-CG2 4.1Å; P120-M152 WeakPolarHBondContact CB-O 3.25Å; P120-M152 HydrophobicContact CG-CB 4.22Å; P120-M156 HydrophobicContact CB-CB 4.4Å; P120-M156 WeakPolarHBondContact O-CA 3.39Å; P120-M156 WeakPolarHBondContact O-CB 3.44Å; P120-M156 VanDerWaalsContact O-CG 3.25Å; P120-M156 WeakPolarHBondContact O-CG 3.41Å
121V95.3Very high94.6Very high0 Ų030.6 Ų30.60%016%0.155CC..Hα-helixtrans-65.5-51.4179.5174.90000110.4I117 P118 L119 L123 G124 I125 Q155 S159 W466I117-V121 HydrophobicContact CG2-CB 4.01Å; I117-V121 HydrophobicContact CG2-CG1 3.69Å; P118-V121 HydrophobicContact CB-CB 4.25Å; P118-V121 HydrophobicContact CB-CG2 4.01Å; P118-V121 HydrophobicContact CG-CG2 4.32Å; P118-V121 WeakPolarHBondContact O-CB 3.33Å; P118-V121 PolarHBondContact O-N 2.9Å; L119-V121 VanDerWaalsContact C-N 3.28Å; L119-V121 PolarHBondContact O-N 3.38Å; V121-L123 VanDerWaalsContact C-N 3.3Å; V121-L123 PolarHBondContact O-N 3.37Å; V121-G124 WeakPolarHBondContact O-CA 3.16Å; V121-G124 PolarHBondContact O-N 3.25Å; V121-G124 VanDerWaalsContact O-N 3.07Å; V121-I125 HydrophobicContact CG1-CD1 3.88Å; V121-I125 HydrophobicContact CG1-CG1 4.27Å; V121-I125 WeakPolarHBondContact O-CG1 3.27Å; V121-I125 PolarHBondContact O-N 3.46Å; V121-Q155 HydrophobicContact CG2-CB 4.11Å; V121-S159 PolarHBondContact O-OG 2.89Å; V121-S159 VanDerWaalsContact O-OG 3.13Å; V121-W466 HydrophobicContact CB-CZ2 4.34Å; V121-W466 HydrophobicContact CG1-CD2 3.69Å; V121-W466 HydrophobicContact CG1-CE3 4.21Å; V121-W466 HydrophobicContact CG1-CG 4.14Å; V121-W466 HydrophobicContact CG1-CH2 4.1Å; V121-W466 HydrophobicContact CG1-CZ2 3.57Å; V121-W466 HydrophobicContact CG1-CZ3 4.4Å; V121-W466 HydrophobicContact CG2-CH2 3.96Å; V121-W466 HydrophobicContact CG2-CZ2 3.76Å
122V96.3Very high94.4Very high1 Ų130 Ų301%0.00615%0.153CC..Hα-helixtrans-65.5-34-175.578.10000112.5T108 H112 I117 P118 L119 G124 I125 F126T108-V122 HydrophobicContact CG2-CG2 3.74Å; H112-V122 HydrophobicContact CB-CB 4.44Å; H112-V122 HydrophobicContact CB-CG1 4.09Å; H112-V122 HydrophobicContact CB-CG2 4.05Å; I117-V122 HydrophobicContact CB-CB 4.22Å; I117-V122 HydrophobicContact CD1-CG2 4.35Å; I117-V122 HydrophobicContact CG2-CB 3.89Å; I117-V122 HydrophobicContact CG2-CG2 4.44Å; P118-V122 PolarHBondContact O-N 3.28Å; L119-V122 HydrophobicContact CD1-CG1 4.31Å; L119-V122 WeakPolarHBondContact O-CG1 3.46Å; L119-V122 PolarHBondContact O-N 2.97Å; V122-G124 VanDerWaalsContact C-N 3.34Å; V122-I125 PolarHBondContact O-N 2.67Å; V122-F126 WeakPolarHBondContact O-CB 3.38Å; V122-F126 PolarHBondContact O-N 3.04Å
123L96Very high94Very high0 Ų028.9 Ų28.90%015%0.148CC..Hα-helixtrans-69.2-34.1174.7-63.6176000112.1L119 V121 S127 L143 M156 P542 L545 A546L119-L123 HydrophobicContact CD1-CD1 4.02Å; L119-L123 HydrophobicContact CD1-CD2 4.49Å; L119-L123 HydrophobicContact CD1-CG 4.09Å; L119-L123 HydrophobicContact CG-CD1 4.03Å; L119-L123 HydrophobicContact CG-CG 4.5Å; L119-L123 VanDerWaalsContact O-CG 3.22Å; L119-L123 WeakPolarHBondContact O-CG 3.4Å; L119-L123 PolarHBondContact O-N 3.46Å; V121-L123 VanDerWaalsContact C-N 3.3Å; V121-L123 PolarHBondContact O-N 3.37Å; L123-S127 WeakPolarHBondContact O-CB 3.16Å; L123-S127 PolarHBondContact O-N 3.47Å; L123-S127 PolarHBondContact O-OG 3.16Å; L123-L143 HydrophobicContact CD1-CD1 4.19Å; L123-L143 HydrophobicContact CD1-CD2 4.13Å; L123-L143 HydrophobicContact CD1-CG 4.26Å; L123-M156 HydrophobicContact CB-CE 3.64Å; L123-M156 HydrophobicContact CB-SD 4.17Å; L123-P542 HydrophobicContact CD2-CB 4.17Å; L123-L545 HydrophobicContact CD2-CB 3.7Å; L123-L545 HydrophobicContact CD2-CD1 4.25Å; L123-A546 HydrophobicContact CD1-CB 3.74Å
124G96.1Very high93.6Very high0 Ų023.1 Ų23.10%012%0.123CC..Hα-helixtrans-67.9-49.117300000111.5P120 V121 V122 F126 S127 G128 M156 S159 Y160P120-G124 PolarHBondContact O-N 3.3Å; P120-G124 VanDerWaalsContact O-N 3.11Å; V121-G124 WeakPolarHBondContact O-CA 3.16Å; V121-G124 PolarHBondContact O-N 3.25Å; V121-G124 VanDerWaalsContact O-N 3.07Å; V122-G124 VanDerWaalsContact C-N 3.34Å; G124-F126 VanDerWaalsContact C-N 3.31Å; G124-F126 PolarHBondContact O-N 3.03Å; G124-S127 PolarHBondContact O-N 3.47Å; G124-S127 VanDerWaalsContact O-N 3.15Å; G124-G128 PolarHBondContact O-N 3.44Å; G124-M156 VanDerWaalsContact CA-O 3.32Å; G124-M156 WeakPolarHBondContact CA-O 3.34Å; G124-S159 WeakPolarHBondContact CA-OG 3.46Å; G124-Y160 WeakPolarHBondContact O-CA 3.18Å
125I97.2Very high93.4Very high0 Ų017.5 Ų17.50%09%0.094CC..Hα-helixtrans-53.7-49.2173.7-61.5173000110I117 V121 V122 S127 G128 A129 A163 W466 Y469 I473I117-I125 HydrophobicContact CG2-CD1 4.42Å; V121-I125 HydrophobicContact CG1-CD1 3.88Å; V121-I125 HydrophobicContact CG1-CG1 4.27Å; V121-I125 WeakPolarHBondContact O-CG1 3.27Å; V121-I125 PolarHBondContact O-N 3.46Å; V122-I125 PolarHBondContact O-N 2.67Å; I125-S127 PolarHBondContact O-N 3.36Å; I125-G128 PolarHBondContact O-N 2.81Å; I125-A129 WeakPolarHBondContact O-CB 3.23Å; I125-A129 PolarHBondContact O-N 2.87Å; I125-A163 HydrophobicContact CG2-CB 4.08Å; I125-A163 WeakPolarHBondContact O-CB 3.11Å; I125-W466 HydrophobicContact CD1-CB 3.74Å; I125-W466 HydrophobicContact CD1-CG 3.86Å; I125-W466 HydrophobicContact CG1-CB 4.09Å; I125-W466 HydrophobicContact CG1-CG 4.43Å; I125-Y469 HydrophobicContact CD1-CD2 4.04Å; I125-I473 HydrophobicContact CG2-CD1 3.85Å
126F97Very high93.3Very high0 Ų012.6 Ų12.60%07%0.072CC..Hα-helixtrans-56.1-51.6177.3168.7-100.4000111.9T108 V122 G124 G128 A129 V130 I473 T541 P542T108-F126 HydrophobicContact CG2-CB 3.81Å; T108-F126 HydrophobicContact CG2-CD2 4.37Å; T108-F126 HydrophobicContact CG2-CG 4.34Å; T108-F126 VanDerWaalsContact OG1-CD2 3.22Å; T108-F126 WeakPolarHBondContact OG1-CD2 3.35Å; V122-F126 WeakPolarHBondContact O-CB 3.38Å; V122-F126 PolarHBondContact O-N 3.04Å; G124-F126 VanDerWaalsContact C-N 3.31Å; G124-F126 PolarHBondContact O-N 3.03Å; F126-G128 VanDerWaalsContact C-N 3.26Å; F126-G128 PolarHBondContact O-N 3.49Å; F126-A129 PolarHBondContact O-N 2.92Å; F126-V130 HydrophobicContact CD2-CG1 4.35Å; F126-V130 HydrophobicContact CE1-CG2 4.33Å; F126-V130 HydrophobicContact CE2-CG1 4.24Å; F126-V130 HydrophobicContact CZ-CG2 4.32Å; F126-V130 WeakPolarHBondContact O-CG1 3.46Å; F126-V130 WeakPolarHBondContact O-CG2 3.45Å; F126-V130 PolarHBondContact O-N 3.39Å; F126-I473 HydrophobicContact CD2-CG2 4.04Å; F126-T541 HydrophobicContact CE1-CG2 3.98Å; F126-T541 HydrophobicContact CE2-CG2 4.22Å; F126-T541 HydrophobicContact CZ-CG2 3.57Å; F126-P542 HydrophobicContact CD1-CG 3.98Å; F126-P542 HydrophobicContact CE1-CG 3.84Å
127S94.9Very high93.1Very high0 Ų05.9 Ų5.90%04%0.036CC..Hα-helixtrans-62.5-35.9-177-58.10000111.8L123 G124 I125 T131 N132 Y160L123-S127 WeakPolarHBondContact O-CB 3.16Å; L123-S127 PolarHBondContact O-N 3.47Å; L123-S127 PolarHBondContact O-OG 3.16Å; G124-S127 PolarHBondContact O-N 3.47Å; G124-S127 VanDerWaalsContact O-N 3.15Å; I125-S127 PolarHBondContact O-N 3.36Å; S127-T131 PolarHBondContact O-N 3.18Å; S127-N132 PolarHBondContact O-N 3.28Å; S127-Y160 VanDerWaalsContact C-CD2 3.48Å; S127-Y160 WeakPolarHBondContact O-CE2 3.45Å
128G94.3Very high92.8Very high0 Ų05.7 Ų5.70%04%0.035CC..Hα-helixtrans-74.3-47.317800000112.5G124 I125 F126 V130 T131 Y164G124-G128 PolarHBondContact O-N 3.44Å; I125-G128 PolarHBondContact O-N 2.81Å; F126-G128 VanDerWaalsContact C-N 3.26Å; F126-G128 PolarHBondContact O-N 3.49Å; G128-V130 PolarHBondContact O-N 3.24Å; G128-T131 PolarHBondContact O-N 2.93Å; G128-Y164 WeakPolarHBondContact O-CA 3.1Å
129A95.2Very high92.7Very high1 Ų12.9 Ų2.91%0.0082%0.017CC..Hα-helixtrans-57.9-24.8178.600000113.2I125 F126 A163 G167 G470 I473 T474I125-A129 WeakPolarHBondContact O-CB 3.23Å; I125-A129 PolarHBondContact O-N 2.87Å; F126-A129 PolarHBondContact O-N 2.92Å; A129-A163 HydrophobicContact CB-CB 4.39Å; A129-G167 WeakPolarHBondContact O-CA 3.26Å; A129-G470 WeakPolarHBondContact CB-O 3.31Å; A129-I473 HydrophobicContact CB-CB 3.86Å; A129-I473 HydrophobicContact CB-CG2 3.74Å; A129-T474 PolarHBondContact O-OG1 2.84Å
130V94.1Very high92.6Very high0 Ų02 Ų20%01%0.012CC..THydrogen-bonded Turntrans-114.116.4-178.1-50.70000112.3F126 G128 N132 I473 M504 T505 R538F126-V130 HydrophobicContact CD2-CG1 4.35Å; F126-V130 HydrophobicContact CE1-CG2 4.33Å; F126-V130 HydrophobicContact CE2-CG1 4.24Å; F126-V130 HydrophobicContact CZ-CG2 4.32Å; F126-V130 WeakPolarHBondContact O-CG1 3.46Å; F126-V130 WeakPolarHBondContact O-CG2 3.45Å; F126-V130 PolarHBondContact O-N 3.39Å; G128-V130 PolarHBondContact O-N 3.24Å; V130-N132 HydrophobicContact CG2-CB 3.89Å; V130-N132 PolarHBondContact O-N 3.22Å; V130-I473 HydrophobicContact CG1-CG2 4.03Å; V130-M504 CarbonylContact C-O 3.42Å; V130-M504 HydrophobicContact CB-SD 3.92Å; V130-M504 HydrophobicContact CG1-SD 3.96Å; V130-T505 PolarHBondContact O-OG1 3.37Å; V130-R538 VanDerWaalsContact CB-CZ 3.46Å
131T90.7Very high92.2Very high13 Ų132.2 Ų2.28%0.081%0.013CC..THydrogen-bonded Turntrans47.736.3173.452.70000114.3S127 G128 Y164 I168 M504S127-T131 PolarHBondContact O-N 3.18Å; G128-T131 PolarHBondContact O-N 2.93Å; T131-Y164 HydrophobicContact CG2-CD2 4.1Å; T131-Y164 HydrophobicContact CG2-CE2 3.9Å; T131-I168 HydrophobicContact CG2-CG1 3.84Å; T131-M504 PolarHBondContact OG1-O 3.42Å
132N90.6Very high91.8Very high1 Ų12.4 Ų2.41%0.0051%0.014CC..  trans-112.786.2-173.1-161-60.1000110.8S127 V130 P134 A135 L136 T505 R538S127-N132 PolarHBondContact O-N 3.28Å; V130-N132 HydrophobicContact CG2-CB 3.89Å; V130-N132 PolarHBondContact O-N 3.22Å; N132-P134 VanDerWaalsContact C-CD 3.46Å; N132-P134 VanDerWaalsContact OD1-CD 3.24Å; N132-P134 WeakPolarHBondContact OD1-CD 3.17Å; N132-A135 HydrophobicContact CB-CB 3.84Å; N132-A135 VanDerWaalsContact O-CB 3.31Å; N132-A135 WeakPolarHBondContact O-CB 3.49Å; N132-A135 PolarHBondContact O-N 2.93Å; N132-A135 VanDerWaalsContact O-N 3.12Å; N132-A135 VanDerWaalsContact OD1-CB 3.28Å; N132-A135 WeakPolarHBondContact OD1-CB 3.08Å; N132-A135 PolarHBondContact OD1-N 3.35Å; N132-L136 PolarHBondContact O-N 3.27Å; N132-T505 PolarHBondContact ND2-OG1 3.45Å; N132-T505 VanDerWaalsContact ND2-OG1 3.09Å; N132-R538 VanDerWaalsContact ND2-CB 3.34Å; N132-R538 WeakPolarHBondContact ND2-CB 3.35Å
133T87.6Confident91.5Very high8 Ų82.4 Ų2.45%0.0491%0.013CC..Hα-helixtrans-57.4-39.3175.4-42.90000113.8F70 A135 L136 G137 Y160 I439 F442 L443F70-T133 HydrophobicContact CE1-CG2 4.37Å; T133-A135 VanDerWaalsContact C-N 3.28Å; T133-A135 PolarHBondContact O-N 3.44Å; T133-L136 WeakPolarHBondContact O-CB 3.35Å; T133-L136 PolarHBondContact O-N 3.43Å; T133-L136 VanDerWaalsContact O-N 3.17Å; T133-G137 PolarHBondContact O-N 2.9Å; T133-Y160 PolarHBondContact OG1-OH 2.95Å; T133-Y160 VanDerWaalsContact OG1-OH 3.05Å; T133-I439 HydrophobicContact CG2-CD1 4.03Å; T133-I439 HydrophobicContact CG2-CG1 4.23Å; T133-F442 HydrophobicContact CG2-CD1 3.63Å; T133-F442 HydrophobicContact CG2-CE1 3.51Å; T133-L443 HydrophobicContact CG2-CD2 3.65Å; T133-L443 HydrophobicContact CG2-CG 4.12Å
134P84.5Confident91Very high4 Ų44.6 Ų4.63%0.0262%0.021CC..Hα-helixtrans-57.3-39.4172.9-26.334.5000113.6F70 V71 I74 N132 L136 G137 A138 I539F70-P134 HydrophobicContact CD1-CG 4.26Å; F70-P134 HydrophobicContact CE1-CB 4.34Å; F70-P134 VanDerWaalsContact CE1-CD 3.45Å; F70-P134 HydrophobicContact CE1-CG 3.36Å; F70-P134 HydrophobicContact CZ-CG 3.81Å; V71-P134 HydrophobicContact CG2-CB 4.1Å; I74-P134 HydrophobicContact CD1-CG 3.95Å; N132-P134 VanDerWaalsContact C-CD 3.46Å; N132-P134 VanDerWaalsContact OD1-CD 3.24Å; N132-P134 WeakPolarHBondContact OD1-CD 3.17Å; P134-L136 VanDerWaalsContact C-N 3.32Å; P134-L136 PolarHBondContact O-N 2.95Å; P134-G137 PolarHBondContact O-N 3.42Å; P134-A138 WeakPolarHBondContact O-CB 3.29Å; P134-A138 PolarHBondContact O-N 3.48Å; P134-I539 HydrophobicContact CB-CD1 3.43Å; P134-I539 VanDerWaalsContact CB-CD1 3.43Å; P134-I539 HydrophobicContact CB-CG1 3.48Å; P134-I539 VanDerWaalsContact CB-CG1 3.48Å; P134-I539 HydrophobicContact CG-CD1 4.26Å
135A91Very high90.3Very high0 Ų07.5 Ų7.50%04%0.037CC..Hα-helixtrans-64-37176.800000111.8N132 T133 A138 G139 R538 P542N132-A135 HydrophobicContact CB-CB 3.84Å; N132-A135 VanDerWaalsContact O-CB 3.31Å; N132-A135 WeakPolarHBondContact O-CB 3.49Å; N132-A135 PolarHBondContact O-N 2.93Å; N132-A135 VanDerWaalsContact O-N 3.12Å; N132-A135 VanDerWaalsContact OD1-CB 3.28Å; N132-A135 WeakPolarHBondContact OD1-CB 3.08Å; N132-A135 PolarHBondContact OD1-N 3.35Å; T133-A135 VanDerWaalsContact C-N 3.28Å; T133-A135 PolarHBondContact O-N 3.44Å; A135-A138 PolarHBondContact O-N 2.75Å; A135-G139 PolarHBondContact O-N 3.33Å; A135-R538 VanDerWaalsContact CB-O 3.29Å; A135-R538 WeakPolarHBondContact CB-O 3.19Å; A135-P542 HydrophobicContact CB-CG 3.79Å
136L92Very high89.7Confident0 Ų08.5 Ų8.50%04%0.042CC..Hα-helixtrans-58.9-52.8172173.864.2000111.1N132 T133 P134 A138 G139 Q140 M156 Y160 F442 V446N132-L136 PolarHBondContact O-N 3.27Å; T133-L136 WeakPolarHBondContact O-CB 3.35Å; T133-L136 PolarHBondContact O-N 3.43Å; T133-L136 VanDerWaalsContact O-N 3.17Å; P134-L136 VanDerWaalsContact C-N 3.32Å; P134-L136 PolarHBondContact O-N 2.95Å; L136-A138 VanDerWaalsContact C-N 3.34Å; L136-A138 PolarHBondContact O-N 2.83Å; L136-G139 PolarHBondContact O-N 3.38Å; L136-Q140 HydrophobicContact CD1-CG 4.12Å; L136-Q140 WeakPolarHBondContact O-CG 3.2Å; L136-Q140 PolarHBondContact O-N 3.21Å; L136-M156 HydrophobicContact CD1-CB 4.34Å; L136-M156 HydrophobicContact CD1-CE 3.86Å; L136-M156 HydrophobicContact CD1-CG 3.62Å; L136-M156 HydrophobicContact CD1-SD 4.06Å; L136-Y160 HydrophobicContact CB-CD2 4.04Å; L136-Y160 HydrophobicContact CB-CE2 4.3Å; L136-Y160 HydrophobicContact CD1-CD2 4.49Å; L136-Y160 HydrophobicContact CD1-CG 4.33Å; L136-Y160 HydrophobicContact CD2-CD1 3.7Å; L136-Y160 HydrophobicContact CD2-CD2 3.97Å; L136-Y160 HydrophobicContact CD2-CE1 4.09Å; L136-Y160 HydrophobicContact CD2-CE2 4.36Å; L136-Y160 HydrophobicContact CD2-CG 3.66Å; L136-Y160 HydrophobicContact CG-CD2 4.39Å; L136-Y160 HydrophobicContact CG-CG 4.39Å; L136-F442 HydrophobicContact CD2-CE1 4.05Å; L136-F442 HydrophobicContact CD2-CZ 4.2Å; L136-F442 HydrophobicContact CG-CE1 4.43Å; L136-F442 HydrophobicContact CG-CZ 4.2Å; L136-V446 HydrophobicContact CD2-CG1 3.92Å; L136-V446 HydrophobicContact CD2-CG2 4.47Å
137G88.2Confident89.1Confident0 Ų011.3 Ų11.30%07%0.071CC..Hα-helixtrans-61.5-42.7-179.600000112.6T133 P134 G139 Q140 Q141T133-G137 PolarHBondContact O-N 2.9Å; P134-G137 PolarHBondContact O-N 3.42Å; G137-G139 VanDerWaalsContact C-N 3.34Å; G137-G139 PolarHBondContact O-N 2.98Å; G137-Q140 PolarHBondContact O-N 2.93Å; G137-Q141 WeakPolarHBondContact O-CB 3.19Å; G137-Q141 PolarHBondContact O-N 3.34Å
138A87Confident88.8Confident0 Ų011.8 Ų11.80%07%0.074CC..Hα-helixtrans-61.8-39.9175.100000112.9P134 A135 L136 I142 A403 I539 Q543P134-A138 WeakPolarHBondContact O-CB 3.29Å; P134-A138 PolarHBondContact O-N 3.48Å; A135-A138 PolarHBondContact O-N 2.75Å; L136-A138 VanDerWaalsContact C-N 3.34Å; L136-A138 PolarHBondContact O-N 2.83Å; A138-I142 PolarHBondContact O-N 3.47Å; A138-I142 VanDerWaalsContact O-N 3.13Å; A138-A403 HydrophobicContact CB-CB 3.75Å; A138-I539 HydrophobicContact CB-CG2 3.94Å; A138-Q543 HydrophobicContact CB-CG 4.34Å
139G91.8Very high88.4Confident0 Ų015.3 Ų15.30%010%0.097CC..Hα-helixtrans-69.5-42.3176.800000113.2A135 L136 G137 Q141 I142 L143 M156A135-G139 PolarHBondContact O-N 3.33Å; L136-G139 PolarHBondContact O-N 3.38Å; G137-G139 VanDerWaalsContact C-N 3.34Å; G137-G139 PolarHBondContact O-N 2.98Å; G139-Q141 VanDerWaalsContact C-N 3.25Å; G139-Q141 PolarHBondContact O-N 3.46Å; G139-I142 WeakPolarHBondContact O-CG2 3.47Å; G139-I142 PolarHBondContact O-N 3.16Å; G139-L143 VanDerWaalsContact O-CG 3.27Å; G139-L143 WeakPolarHBondContact O-CG 3.38Å; G139-L143 PolarHBondContact O-N 3.49Å; G139-L143 VanDerWaalsContact O-N 3.13Å; G139-M156 VanDerWaalsContact C-SD 3.52Å
140Q91.3Very high87.8Confident2 Ų218.7 Ų18.71%0.00911%0.114CC..Hα-helixtrans-61.5-39.3174.8-72.9-177.1-44.600111.1L136 G137 R144 V153 M156L136-Q140 HydrophobicContact CD1-CG 4.12Å; L136-Q140 WeakPolarHBondContact O-CG 3.2Å; L136-Q140 PolarHBondContact O-N 3.21Å; G137-Q140 PolarHBondContact O-N 2.93Å; Q140-R144 WeakPolarHBondContact O-CG 3.41Å; Q140-R144 PolarHBondContact O-N 3.41Å; Q140-V153 HydrophobicContact CB-CG1 3.78Å; Q140-V153 HydrophobicContact CG-CG1 3.85Å; Q140-M156 HydrophobicContact CB-SD 4.48Å; Q140-M156 HydrophobicContact CG-CB 4.3Å; Q140-M156 HydrophobicContact CG-CG 4.37Å; Q140-M156 HydrophobicContact CG-SD 3.75Å; Q140-M156 PolarHBondContact N-SD 3.4Å; Q140-M156 VanDerWaalsContact N-SD 3.42Å
141Q85.5Confident87.2Confident17 Ų1726.5 Ų26.58%0.07915%0.15CC..Hα-helixtrans-65.6-50.1178.7-179.9158.219.100113.2G137 G139 L143 R144 D145G137-Q141 WeakPolarHBondContact O-CB 3.19Å; G137-Q141 PolarHBondContact O-N 3.34Å; G139-Q141 VanDerWaalsContact C-N 3.25Å; G139-Q141 PolarHBondContact O-N 3.46Å; Q141-L143 VanDerWaalsContact C-N 3.26Å; Q141-L143 PolarHBondContact O-N 3.29Å; Q141-R144 WeakPolarHBondContact O-CB 3.46Å; Q141-R144 PolarHBondContact O-N 3.29Å; Q141-R144 VanDerWaalsContact O-N 3.16Å; Q141-D145 PolarHBondContact O-N 3.34Å
142I86Confident87.1Confident4 Ų430.5 Ų30.52%0.02117%0.169CC..Hα-helixtrans-63.1-35.6-179.5-171.560.4000111.6A138 G139 R144 D145 L146 L398 Q543 A546 V547A138-I142 PolarHBondContact O-N 3.47Å; A138-I142 VanDerWaalsContact O-N 3.13Å; G139-I142 WeakPolarHBondContact O-CG2 3.47Å; G139-I142 PolarHBondContact O-N 3.16Å; I142-R144 VanDerWaalsContact C-N 3.33Å; I142-R144 PolarHBondContact O-N 3.17Å; I142-D145 PolarHBondContact O-N 3.35Å; I142-L146 HydrophobicContact CD1-CG 4.49Å; I142-L146 HydrophobicContact CG1-CD1 4.14Å; I142-L146 HydrophobicContact CG1-CG 4.4Å; I142-L146 WeakPolarHBondContact O-CB 3.44Å; I142-L146 VanDerWaalsContact O-CG 3.26Å; I142-L146 WeakPolarHBondContact O-CG 3.42Å; I142-L146 PolarHBondContact O-N 3.07Å; I142-L398 HydrophobicContact CD1-CD2 4.22Å; I142-Q543 HydrophobicContact CB-CG 4.27Å; I142-Q543 HydrophobicContact CG2-CG 4.27Å; I142-A546 HydrophobicContact CG1-CB 4.3Å; I142-A546 HydrophobicContact CG2-CB 3.73Å; I142-V547 HydrophobicContact CD1-CG2 4.03Å; I142-V547 HydrophobicContact CG1-CG2 3.94Å
143L90.1Very high87.1Confident0 Ų030.5 Ų30.50%017%0.169CC..Hα-helixtrans-63.2-40.6176.3-71.7171.8000111.6L119 P120 L123 G139 Q141 L146 G147 T148 V153 M156 A546L119-L143 HydrophobicContact CD2-CD2 4.01Å; L119-L143 HydrophobicContact CG-CD2 4.19Å; P120-L143 HydrophobicContact CB-CD1 3.87Å; P120-L143 HydrophobicContact CG-CD1 4.11Å; L123-L143 HydrophobicContact CD1-CD1 4.19Å; L123-L143 HydrophobicContact CD1-CD2 4.13Å; L123-L143 HydrophobicContact CD1-CG 4.26Å; G139-L143 VanDerWaalsContact O-CG 3.27Å; G139-L143 WeakPolarHBondContact O-CG 3.38Å; G139-L143 PolarHBondContact O-N 3.49Å; G139-L143 VanDerWaalsContact O-N 3.13Å; Q141-L143 VanDerWaalsContact C-N 3.26Å; Q141-L143 PolarHBondContact O-N 3.29Å; L143-L146 PolarHBondContact O-N 3.06Å; L143-G147 PolarHBondContact O-N 2.99Å; L143-T148 WeakPolarHBondContact O-CB 3.25Å; L143-T148 PolarHBondContact O-N 3.3Å; L143-T148 PolarHBondContact O-OG1 2.99Å; L143-V153 HydrophobicContact CB-CG2 3.96Å; L143-M156 HydrophobicContact CD1-SD 3.83Å; L143-A546 HydrophobicContact CD2-CB 4.46Å
144R86.2Confident87Confident46 Ų4631.9 Ų31.917%0.17418%0.176CC..Hα-helixtrans-64.9-42.6173.6-69.6-178.5-57.7-123.75.3111.9E64 Q140 Q141 I142 L146 G147 M150 V153E64-R144 IonicContact OE1-CZ 2.81Å; E64-R144 VanDerWaalsContact OE1-CZ 3.26Å; E64-R144 IonicContact OE1-NH1 3.24Å; E64-R144 PolarHBondContact OE1-NH1 3.45Å; E64-R144 VanDerWaalsContact OE1-NH1 3.17Å; E64-R144 IonicContact OE1-NH2 3.26Å; E64-R144 PolarHBondContact OE1-NH2 3.2Å; E64-R144 IonicContact OE2-NH2 3.83Å; E64-R144 PolarHBondContact OE2-NH2 2.7Å; Q140-R144 WeakPolarHBondContact O-CG 3.41Å; Q140-R144 PolarHBondContact O-N 3.41Å; Q141-R144 WeakPolarHBondContact O-CB 3.46Å; Q141-R144 PolarHBondContact O-N 3.29Å; Q141-R144 VanDerWaalsContact O-N 3.16Å; I142-R144 VanDerWaalsContact C-N 3.33Å; I142-R144 PolarHBondContact O-N 3.17Å; R144-L146 PolarHBondContact O-N 2.69Å; R144-G147 PolarHBondContact O-N 3.29Å; R144-M150 HydrophobicContact CG-SD 4.05Å; R144-V153 HydrophobicContact CG-CG1 4.33Å; R144-V153 HydrophobicContact CG-CG2 4.05Å
145D81.6Confident87.3Confident62 Ų6235 Ų3533%0.33219%0.191SC..Hα-helixtrans-64.3-31.5177.9-72.6-22.2000112Q141 I142 G147Q141-D145 PolarHBondContact O-N 3.34Å; I142-D145 PolarHBondContact O-N 3.35Å; D145-G147 PolarHBondContact O-N 3.07Å
146L84.1Confident87.5Confident20 Ų2035 Ų3511%0.10519%0.191CC..THydrogen-bonded Turntrans-77-5.8172.4-68.5171.5000113.6I142 L143 R144 A396 A546 W550I142-L146 HydrophobicContact CD1-CG 4.49Å; I142-L146 HydrophobicContact CG1-CD1 4.14Å; I142-L146 HydrophobicContact CG1-CG 4.4Å; I142-L146 WeakPolarHBondContact O-CB 3.44Å; I142-L146 VanDerWaalsContact O-CG 3.26Å; I142-L146 WeakPolarHBondContact O-CG 3.42Å; I142-L146 PolarHBondContact O-N 3.07Å; L143-L146 PolarHBondContact O-N 3.06Å; R144-L146 PolarHBondContact O-N 2.69Å; L146-A396 HydrophobicContact CD2-CB 4.09Å; L146-A546 HydrophobicContact CD1-CB 4.27Å; L146-W550 HydrophobicContact CB-CD2 4.15Å; L146-W550 HydrophobicContact CB-CE3 4.46Å; L146-W550 HydrophobicContact CB-CZ2 4.44Å; L146-W550 HydrophobicContact CD1-CB 3.98Å; L146-W550 HydrophobicContact CD1-CD2 4.18Å; L146-W550 HydrophobicContact CD1-CE3 4.46Å; L146-W550 HydrophobicContact CD1-CG 3.96Å; L146-W550 HydrophobicContact CD2-CG 4.18Å; L146-W550 HydrophobicContact CG-CG 4.46Å; L146-W550 VanDerWaalsContact O-CZ2 3.28Å; L146-W550 WeakPolarHBondContact O-CZ2 3.14Å
147G84.2Confident87.5Confident59 Ų5935 Ų3561%0.60819%0.191SC*.THydrogen-bonded Turntrans86.318.1178.900000114.8L143 R144 D145L143-G147 PolarHBondContact O-N 2.99Å; R144-G147 PolarHBondContact O-N 3.29Å; D145-G147 PolarHBondContact O-N 3.07Å
148T88Confident87.7Confident10 Ų1035.6 Ų35.66%0.06119%0.193CC..  trans-65131174.2-55.40000109.9P120 L143 M152 V153 W550P120-T148 HydrophobicContact CG-CG2 4.1Å; L143-T148 WeakPolarHBondContact O-CB 3.25Å; L143-T148 PolarHBondContact O-N 3.3Å; L143-T148 PolarHBondContact O-OG1 2.99Å; T148-M152 HydrophobicContact CG2-CB 3.79Å; T148-M152 HydrophobicContact CG2-SD 4.47Å; T148-V153 HydrophobicContact CG2-CG2 3.99Å; T148-W550 WeakPolarHBondContact OG1-CZ3 3.28Å
149P87.5Confident88.1Confident74 Ų7435.6 Ų35.648%0.48119%0.193SC..  trans-55.1141.4177.5-25.934.2000112.6E151 M152 V153P149-E151 VanDerWaalsContact C-N 3.28Å; P149-E151 PolarHBondContact O-N 3.47Å; P149-M152 HydrophobicContact CG-SD 4.34Å; P149-M152 WeakPolarHBondContact O-CB 3.25Å; P149-M152 PolarHBondContact O-N 3.18Å; P149-V153 PolarHBondContact O-N 2.88Å; P149-V153 VanDerWaalsContact O-N 3.12Å
150M82.6Confident88.2Confident72 Ų7235.6 Ų35.636%0.35519%0.193SC..Hα-helixtrans-56.7-37.9-176.1-94.7-59.6-52.500113.6R144 M152 V153 D154R144-M150 HydrophobicContact CG-SD 4.05Å; M150-M152 VanDerWaalsContact C-N 3.27Å; M150-M152 PolarHBondContact O-N 3.45Å; M150-V153 WeakPolarHBondContact O-CB 3.41Å; M150-V153 PolarHBondContact O-N 3.13Å; M150-V153 VanDerWaalsContact O-N 3.08Å; M150-V153 HydrophobicContact SD-CB 4.45Å; M150-D154 WeakPolarHBondContact CE-OD1 3.43Å; M150-D154 PolarHBondContact O-N 3.3Å
151E81.8Confident88.3Confident165 Ų16535.5 Ų35.577%0.77119%0.193SC*.Hα-helixtrans-60.2-37.8177.1-67.2178.5176.300112.1P149 D154P149-E151 VanDerWaalsContact C-N 3.28Å; P149-E151 PolarHBondContact O-N 3.47Å; E151-D154 PolarHBondContact O-N 3.42Å
152M87.8Confident88.7Confident97 Ų9734.9 Ų34.948%0.47819%0.19SC..Hα-helixtrans-72.8-34175.1-70-175.2175.900111.8P120 T148 P149 M150 D154 Q155P120-M152 WeakPolarHBondContact CB-O 3.25Å; P120-M152 HydrophobicContact CG-CB 4.22Å; T148-M152 HydrophobicContact CG2-CB 3.79Å; T148-M152 HydrophobicContact CG2-SD 4.47Å; P149-M152 HydrophobicContact CG-SD 4.34Å; P149-M152 WeakPolarHBondContact O-CB 3.25Å; P149-M152 PolarHBondContact O-N 3.18Å; M150-M152 VanDerWaalsContact C-N 3.27Å; M150-M152 PolarHBondContact O-N 3.45Å; M152-D154 VanDerWaalsContact C-N 3.28Å; M152-D154 PolarHBondContact O-N 2.98Å; M152-Q155 WeakPolarHBondContact O-CB 3.32Å; M152-Q155 PolarHBondContact O-N 3.22Å
153V89.5Confident89.1Confident0 Ų034.7 Ų34.70%019%0.189CC..Hα-helixtrans-65.3-33.6174.8178.40000111.4Q140 L143 R144 T148 P149 M150 Q155 M156Q140-V153 HydrophobicContact CB-CG1 3.78Å; Q140-V153 HydrophobicContact CG-CG1 3.85Å; L143-V153 HydrophobicContact CB-CG2 3.96Å; R144-V153 HydrophobicContact CG-CG1 4.33Å; R144-V153 HydrophobicContact CG-CG2 4.05Å; T148-V153 HydrophobicContact CG2-CG2 3.99Å; P149-V153 PolarHBondContact O-N 2.88Å; P149-V153 VanDerWaalsContact O-N 3.12Å; M150-V153 WeakPolarHBondContact O-CB 3.41Å; M150-V153 PolarHBondContact O-N 3.13Å; M150-V153 VanDerWaalsContact O-N 3.08Å; M150-V153 HydrophobicContact SD-CB 4.45Å; V153-Q155 VanDerWaalsContact C-N 3.27Å; V153-Q155 PolarHBondContact O-N 2.87Å; V153-M156 WeakPolarHBondContact O-CB 3.47Å; V153-M156 PolarHBondContact O-N 2.74Å; V153-M156 VanDerWaalsContact O-N 3.1Å
154D86.7Confident89.1Confident38 Ų3835.7 Ų35.720%0.20319%0.193CC..Hα-helixtrans-68-27.2177.4-71.3-16.5000112.2M150 E151 M152 M156 G157 M158 K449M150-D154 WeakPolarHBondContact CE-OD1 3.43Å; M150-D154 PolarHBondContact O-N 3.3Å; E151-D154 PolarHBondContact O-N 3.42Å; M152-D154 VanDerWaalsContact C-N 3.28Å; M152-D154 PolarHBondContact O-N 2.98Å; D154-M156 PolarHBondContact O-N 3.23Å; D154-G157 PolarHBondContact O-N 3Å; D154-M158 PolarHBondContact O-N 2.97Å; D154-K449 WeakPolarHBondContact OD1-CD 3.22Å; D154-K449 IonicContact OD1-NZ 2.67Å
155Q91.5Very high89.1Confident70 Ų7035.5 Ų35.533%0.32720%0.197SC..Hα-helixtrans-61.2-27170.9-60.6-178.3-16.500112.8V121 M152 V153 G157 M158 S159V121-Q155 HydrophobicContact CG2-CB 4.11Å; M152-Q155 WeakPolarHBondContact O-CB 3.32Å; M152-Q155 PolarHBondContact O-N 3.22Å; V153-Q155 VanDerWaalsContact C-N 3.27Å; V153-Q155 PolarHBondContact O-N 2.87Å; Q155-G157 VanDerWaalsContact C-N 3.32Å; Q155-M158 PolarHBondContact O-N 3.35Å; Q155-S159 WeakPolarHBondContact O-CB 3.41Å; Q155-S159 PolarHBondContact O-N 2.76Å; Q155-S159 PolarHBondContact O-OG 3.04Å
156M94.4Very high89.4Confident0 Ų036.8 Ų36.80%020%0.2CC..Hα-helixtrans-64.5-38.5174.2-167.9179.5173.300111.3P120 L123 G124 L136 G139 Q140 L143 V153 D154 S159 Y160P120-M156 HydrophobicContact CB-CB 4.4Å; P120-M156 WeakPolarHBondContact O-CA 3.39Å; P120-M156 WeakPolarHBondContact O-CB 3.44Å; P120-M156 VanDerWaalsContact O-CG 3.25Å; P120-M156 WeakPolarHBondContact O-CG 3.41Å; L123-M156 HydrophobicContact CB-CE 3.64Å; L123-M156 HydrophobicContact CB-SD 4.17Å; G124-M156 VanDerWaalsContact CA-O 3.32Å; G124-M156 WeakPolarHBondContact CA-O 3.34Å; L136-M156 HydrophobicContact CD1-CB 4.34Å; L136-M156 HydrophobicContact CD1-CE 3.86Å; L136-M156 HydrophobicContact CD1-CG 3.62Å; L136-M156 HydrophobicContact CD1-SD 4.06Å; G139-M156 VanDerWaalsContact C-SD 3.52Å; Q140-M156 HydrophobicContact CB-SD 4.48Å; Q140-M156 HydrophobicContact CG-CB 4.3Å; Q140-M156 HydrophobicContact CG-CG 4.37Å; Q140-M156 HydrophobicContact CG-SD 3.75Å; Q140-M156 PolarHBondContact N-SD 3.4Å; Q140-M156 VanDerWaalsContact N-SD 3.42Å; L143-M156 HydrophobicContact CD1-SD 3.83Å; V153-M156 WeakPolarHBondContact O-CB 3.47Å; V153-M156 PolarHBondContact O-N 2.74Å; V153-M156 VanDerWaalsContact O-N 3.1Å; D154-M156 PolarHBondContact O-N 3.23Å; M156-S159 WeakPolarHBondContact CA-OG 3.39Å; M156-S159 PolarHBondContact O-OG 2.97Å; M156-Y160 WeakPolarHBondContact O-CB 3.27Å; M156-Y160 PolarHBondContact O-N 3.38Å
157G92Very high89.7Confident0 Ų035.9 Ų35.90%020%0.196CC..Hα-helixtrans-66.4-40.8175.100000112.4D154 Q155 Y160 A161 S450D154-G157 PolarHBondContact O-N 3Å; Q155-G157 VanDerWaalsContact C-N 3.32Å; G157-Y160 WeakPolarHBondContact O-CB 3.25Å; G157-A161 PolarHBondContact O-N 3.46Å; G157-A161 VanDerWaalsContact O-N 3.08Å; G157-S450 VanDerWaalsContact C-OG 3.26Å
158M92.4Very high89.8Confident11 Ų1133.4 Ų33.45%0.05417%0.169CC..Hα-helixtrans-67.2-48.8-179.9-165.3-167.7-43.900112D154 Q155 Y160 A161 M162 S450 D453 F454 T457 W466D154-M158 PolarHBondContact O-N 2.97Å; Q155-M158 PolarHBondContact O-N 3.35Å; M158-Y160 VanDerWaalsContact C-N 3.34Å; M158-Y160 PolarHBondContact O-N 3.24Å; M158-A161 WeakPolarHBondContact O-CB 3.49Å; M158-A161 PolarHBondContact O-N 3.49Å; M158-A161 VanDerWaalsContact O-N 3.12Å; M158-M162 HydrophobicContact CG-CE 4.11Å; M158-M162 WeakPolarHBondContact O-CG 3.45Å; M158-M162 PolarHBondContact O-N 2.79Å; M158-M162 VanDerWaalsContact O-N 3.1Å; M158-M162 HydrophobicContact SD-CE 4.26Å; M158-S450 PolarHBondContact N-OG 3.12Å; M158-D453 HydrophobicContact CE-CB 3.66Å; M158-D453 HydrophobicContact SD-CB 4.25Å; M158-F454 HydrophobicContact CG-CB 4.5Å; M158-F454 HydrophobicContact CG-CD2 3.94Å; M158-T457 HydrophobicContact SD-CG2 3.93Å; M158-T457 PolarHBondContact SD-OG1 2.83Å; M158-W466 HydrophobicContact SD-CZ3 4.31Å
159S95.3Very high89.8Confident0 Ų036.7 Ų36.70%019%0.191CC..Hα-helixtrans-66-34.7177.7540000112.8V121 G124 Q155 M156 A161 M162 A163V121-S159 PolarHBondContact O-OG 2.89Å; V121-S159 VanDerWaalsContact O-OG 3.13Å; G124-S159 WeakPolarHBondContact CA-OG 3.46Å; Q155-S159 WeakPolarHBondContact O-CB 3.41Å; Q155-S159 PolarHBondContact O-N 2.76Å; Q155-S159 PolarHBondContact O-OG 3.04Å; M156-S159 WeakPolarHBondContact CA-OG 3.39Å; M156-S159 PolarHBondContact O-OG 2.97Å; S159-A161 PolarHBondContact O-N 2.87Å; S159-M162 PolarHBondContact O-N 2.79Å; S159-A163 PolarHBondContact O-N 3.37Å; S159-A163 VanDerWaalsContact O-N 3.09Å
160Y94.6Very high90Very high0 Ų033.9 Ų33.90%018%0.176CC..Hα-helixtrans-56.1-48.1167.6168.3-91.4000111.9L37 G124 S127 T133 L136 M156 G157 M158 M162 A163 Y164 L443L37-Y160 HydrophobicContact CD1-CD1 4.2Å; L37-Y160 HydrophobicContact CD1-CE1 4.26Å; L37-Y160 HydrophobicContact CD2-CD1 3.65Å; L37-Y160 HydrophobicContact CD2-CE1 3.46Å; L37-Y160 VanDerWaalsContact CD2-CE1 3.46Å; L37-Y160 HydrophobicContact CG-CE1 4.43Å; G124-Y160 WeakPolarHBondContact O-CA 3.18Å; S127-Y160 VanDerWaalsContact C-CD2 3.48Å; S127-Y160 WeakPolarHBondContact O-CE2 3.45Å; T133-Y160 PolarHBondContact OG1-OH 2.95Å; T133-Y160 VanDerWaalsContact OG1-OH 3.05Å; L136-Y160 HydrophobicContact CB-CD2 4.04Å; L136-Y160 HydrophobicContact CB-CE2 4.3Å; L136-Y160 HydrophobicContact CD1-CD2 4.49Å; L136-Y160 HydrophobicContact CD1-CG 4.33Å; L136-Y160 HydrophobicContact CD2-CD1 3.7Å; L136-Y160 HydrophobicContact CD2-CD2 3.97Å; L136-Y160 HydrophobicContact CD2-CE1 4.09Å; L136-Y160 HydrophobicContact CD2-CE2 4.36Å; L136-Y160 HydrophobicContact CD2-CG 3.66Å; L136-Y160 HydrophobicContact CG-CD2 4.39Å; L136-Y160 HydrophobicContact CG-CG 4.39Å; M156-Y160 WeakPolarHBondContact O-CB 3.27Å; M156-Y160 PolarHBondContact O-N 3.38Å; G157-Y160 WeakPolarHBondContact O-CB 3.25Å; M158-Y160 VanDerWaalsContact C-N 3.34Å; M158-Y160 PolarHBondContact O-N 3.24Å; Y160-M162 VanDerWaalsContact C-N 3.3Å; Y160-M162 PolarHBondContact O-N 3.47Å; Y160-A163 PolarHBondContact O-N 3.49Å; Y160-Y164 HydrophobicContact CE1-CD2 4.18Å; Y160-Y164 HydrophobicContact CE2-CD2 4.17Å; Y160-Y164 AromaticContact CZ-CD2 3.62Å; Y160-Y164 WeakPolarHBondContact O-CB 3.41Å; Y160-Y164 PolarHBondContact O-N 3.5Å; Y160-Y164 VanDerWaalsContact OH-CD2 3.27Å; Y160-Y164 WeakPolarHBondContact OH-CD2 3.5Å; Y160-Y164 VanDerWaalsContact OH-CE2 3.24Å; Y160-Y164 WeakPolarHBondContact OH-CE2 3.31Å; Y160-L443 HydrophobicContact CE1-CD2 4.36Å
161A92.7Very high90.5Very high0 Ų030.5 Ų30.50%016%0.159CC..Hα-helixtrans-64.4-34.1-179.800000113.5L37 I41 G157 M158 S159 P165 F454L37-A161 HydrophobicContact CD1-CB 4.28Å; L37-A161 HydrophobicContact CD2-CB 3.47Å; L37-A161 VanDerWaalsContact CD2-CB 3.47Å; L37-A161 HydrophobicContact CG-CB 3.94Å; I41-A161 HydrophobicContact CD1-CB 3.44Å; I41-A161 VanDerWaalsContact CD1-CB 3.44Å; G157-A161 PolarHBondContact O-N 3.46Å; G157-A161 VanDerWaalsContact O-N 3.08Å; M158-A161 WeakPolarHBondContact O-CB 3.49Å; M158-A161 PolarHBondContact O-N 3.49Å; M158-A161 VanDerWaalsContact O-N 3.12Å; S159-A161 PolarHBondContact O-N 2.87Å; A161-P165 VanDerWaalsContact O-CD 3.29Å; A161-P165 WeakPolarHBondContact O-CD 3.24Å; A161-F454 HydrophobicContact CB-CD2 4.41Å; A161-F454 HydrophobicContact CB-CE2 3.83Å
162M93.2Very high90.9Very high4 Ų423.6 Ų23.62%0.0213%0.128CC..Hα-helixtrans-69.3-40.8176.2-66.4-172-178.800112.3M158 S159 Y160 F454 T457 L458 G463 W466 I467M158-M162 HydrophobicContact CG-CE 4.11Å; M158-M162 WeakPolarHBondContact O-CG 3.45Å; M158-M162 PolarHBondContact O-N 2.79Å; M158-M162 VanDerWaalsContact O-N 3.1Å; M158-M162 HydrophobicContact SD-CE 4.26Å; S159-M162 PolarHBondContact O-N 2.79Å; Y160-M162 VanDerWaalsContact C-N 3.3Å; Y160-M162 PolarHBondContact O-N 3.47Å; M162-F454 HydrophobicContact CE-CD2 3.94Å; M162-F454 HydrophobicContact CE-CE2 3.98Å; M162-F454 HydrophobicContact CE-CG 4.42Å; M162-F454 HydrophobicContact CE-CZ 4.5Å; M162-F454 HydrophobicContact CG-CD2 4.29Å; M162-F454 HydrophobicContact CG-CE2 3.5Å; M162-F454 VanDerWaalsContact CG-CE2 3.5Å; M162-F454 HydrophobicContact CG-CZ 3.97Å; M162-T457 HydrophobicContact CE-CG2 3.57Å; M162-T457 HydrophobicContact SD-CG2 4.3Å; M162-L458 HydrophobicContact CE-CB 4.13Å; M162-G463 WeakPolarHBondContact SD-CA 3.4Å; M162-W466 HydrophobicContact CE-CE3 4.4Å; M162-W466 HydrophobicContact CE-CZ3 4.39Å; M162-W466 HydrophobicContact SD-CD2 4.32Å; M162-W466 HydrophobicContact SD-CE3 3.45Å; M162-W466 HydrophobicContact SD-CZ3 4Å; M162-I467 HydrophobicContact CB-CG1 4.19Å
163A94.5Very high91.2Very high0 Ų024.2 Ų24.20%013%0.128CC..Hα-helixtrans-78.6-25.6-179.800000113.7I125 A129 S159 Y160 F166 G167I125-A163 HydrophobicContact CG2-CB 4.08Å; I125-A163 WeakPolarHBondContact O-CB 3.11Å; A129-A163 HydrophobicContact CB-CB 4.39Å; S159-A163 PolarHBondContact O-N 3.37Å; S159-A163 VanDerWaalsContact O-N 3.09Å; Y160-A163 PolarHBondContact O-N 3.49Å; A163-F166 PolarHBondContact O-N 3.17Å; A163-F166 VanDerWaalsContact O-N 3.14Å; A163-G167 PolarHBondContact O-N 2.88Å
164Y90.1Very high91.4Very high22 Ų2224.2 Ų24.29%0.08613%0.128CC..Hα-helixtrans-56.5-47.5-171.8-172.6-94.8000115.4F38 G128 T131 Y160 F166 G167 I168F38-Y164 HydrophobicContact CE2-CD1 4.06Å; F38-Y164 HydrophobicContact CZ-CD1 4.39Å; G128-Y164 WeakPolarHBondContact O-CA 3.1Å; T131-Y164 HydrophobicContact CG2-CD2 4.1Å; T131-Y164 HydrophobicContact CG2-CE2 3.9Å; Y160-Y164 HydrophobicContact CE1-CD2 4.18Å; Y160-Y164 HydrophobicContact CE2-CD2 4.17Å; Y160-Y164 AromaticContact CZ-CD2 3.62Å; Y160-Y164 WeakPolarHBondContact O-CB 3.41Å; Y160-Y164 PolarHBondContact O-N 3.5Å; Y160-Y164 VanDerWaalsContact OH-CD2 3.27Å; Y160-Y164 WeakPolarHBondContact OH-CD2 3.5Å; Y160-Y164 VanDerWaalsContact OH-CE2 3.24Å; Y160-Y164 WeakPolarHBondContact OH-CE2 3.31Å; Y164-F166 PolarHBondContact O-N 3.5Å; Y164-G167 PolarHBondContact O-N 2.89Å; Y164-G167 VanDerWaalsContact O-N 3.11Å; Y164-I168 HydrophobicContact CD1-CD1 4.13Å; Y164-I168 HydrophobicContact CE1-CD1 3.5Å; Y164-I168 HydrophobicContact CE1-CG1 4.36Å; Y164-I168 PolarHBondContact O-N 3.43Å
165P86.7Confident91.8Very high41 Ų4122.4 Ų22.427%0.26612%0.118SC..Hα-helixtrans-60.4-36177.6-24.435.5000112.9F38 A161 G167 I168 C169F38-P165 HydrophobicContact CE1-CG 4.21Å; F38-P165 HydrophobicContact CZ-CG 3.62Å; A161-P165 VanDerWaalsContact O-CD 3.29Å; A161-P165 WeakPolarHBondContact O-CD 3.24Å; P165-G167 VanDerWaalsContact C-N 3.35Å; P165-I168 PolarHBondContact O-N 3.21Å; P165-C169 WeakPolarHBondContact O-CB 3.4Å; P165-C169 PolarHBondContact O-N 2.67Å; P165-C169 PolarHBondContact O-SG 3.05Å; P165-C169 VanDerWaalsContact O-SG 3.36Å
166F87.9Confident91.9Very high89 Ų8925.7 Ų25.739%0.3913%0.128SC..Hα-helixtrans-75.4-25.7178.7-74.1-91000112.3A163 Y164 G170 I467 A471A163-F166 PolarHBondContact O-N 3.17Å; A163-F166 VanDerWaalsContact O-N 3.14Å; Y164-F166 PolarHBondContact O-N 3.5Å; F166-G170 VanDerWaalsContact O-CA 3.24Å; F166-G170 WeakPolarHBondContact O-CA 3.46Å; F166-G170 PolarHBondContact O-N 3.21Å; F166-I467 HydrophobicContact CD1-CG2 4.25Å; F166-I467 HydrophobicContact CD2-CB 4.42Å; F166-I467 HydrophobicContact CD2-CG1 4.3Å; F166-I467 HydrophobicContact CD2-CG2 3.55Å; F166-I467 HydrophobicContact CE1-CG2 3.94Å; F166-I467 HydrophobicContact CE2-CB 4.23Å; F166-I467 HydrophobicContact CE2-CD1 4.22Å; F166-I467 HydrophobicContact CE2-CG1 4.08Å; F166-I467 HydrophobicContact CE2-CG2 3.19Å; F166-I467 HydrophobicContact CG-CG2 4.07Å; F166-I467 HydrophobicContact CZ-CG2 3.4Å; F166-A471 HydrophobicContact CD1-CB 4.41Å
167G89.8Confident91.9Very high2 Ų227.3 Ų27.32%0.02114%0.136CC..Hα-helixtrans-57.4-54.916600000111.6A129 A163 Y164 P165 G170 I171A129-G167 WeakPolarHBondContact O-CA 3.26Å; A163-G167 PolarHBondContact O-N 2.88Å; Y164-G167 PolarHBondContact O-N 2.89Å; Y164-G167 VanDerWaalsContact O-N 3.11Å; P165-G167 VanDerWaalsContact C-N 3.35Å; G167-G170 PolarHBondContact O-N 3.38Å; G167-I171 WeakPolarHBondContact O-CG2 3.37Å; G167-I171 PolarHBondContact O-N 3.13Å
168I86.7Confident92Very high7 Ų727.4 Ų27.44%0.03614%0.136CC..Hα-helixtrans-63.7-50.5179.9-60.9176.2000111.3L31 T131 Y164 P165 G170 I171 L172 P508L31-I168 HydrophobicContact CD2-CD1 4.28Å; T131-I168 HydrophobicContact CG2-CG1 3.84Å; Y164-I168 HydrophobicContact CD1-CD1 4.13Å; Y164-I168 HydrophobicContact CE1-CD1 3.5Å; Y164-I168 HydrophobicContact CE1-CG1 4.36Å; Y164-I168 PolarHBondContact O-N 3.43Å; P165-I168 PolarHBondContact O-N 3.21Å; I168-G170 VanDerWaalsContact C-N 3.34Å; I168-G170 PolarHBondContact O-N 3.47Å; I168-I171 WeakPolarHBondContact O-CG2 3.44Å; I168-L172 HydrophobicContact CG2-CD1 4.34Å; I168-L172 WeakPolarHBondContact O-CG 3.34Å; I168-L172 PolarHBondContact O-N 3.46Å; I168-P508 HydrophobicContact CG2-CB 4.43Å
169C88.5Confident92.1Very high79 Ų7931.7 Ų31.753%0.53415%0.151SC..Hα-helixtrans-66.3-39.1-178.9-70.70000111.8P165 I171 L172 F173P165-C169 WeakPolarHBondContact O-CB 3.4Å; P165-C169 PolarHBondContact O-N 2.67Å; P165-C169 PolarHBondContact O-SG 3.05Å; P165-C169 VanDerWaalsContact O-SG 3.36Å; C169-I171 PolarHBondContact O-N 2.91Å; C169-L172 PolarHBondContact O-N 3.32Å; C169-F173 VanDerWaalsContact O-CB 3.3Å; C169-F173 WeakPolarHBondContact O-CB 3.49Å; C169-F173 PolarHBondContact O-N 2.96Å
170G91.8Very high92.1Very high15 Ų1535.5 Ų35.516%0.15518%0.175CC..Hα-helixtrans-65.3-39.2-176.700000112.6F166 G167 I168 T174F166-G170 VanDerWaalsContact O-CA 3.24Å; F166-G170 WeakPolarHBondContact O-CA 3.46Å; F166-G170 PolarHBondContact O-N 3.21Å; G167-G170 PolarHBondContact O-N 3.38Å; I168-G170 VanDerWaalsContact C-N 3.34Å; I168-G170 PolarHBondContact O-N 3.47Å; G170-T174 WeakPolarHBondContact O-CB 3.36Å; G170-T174 PolarHBondContact O-N 3.38Å; G170-T174 PolarHBondContact O-OG1 2.76Å
171I92.5Very high92.1Very high0 Ų039.8 Ų39.80%020%0.197CC..Hα-helixtrans-69.3-42.7175.6-173.4165000112.3G167 I168 C169 F173 T174 M175 L478 L500 M504 D506 A509G167-I171 WeakPolarHBondContact O-CG2 3.37Å; G167-I171 PolarHBondContact O-N 3.13Å; I168-I171 WeakPolarHBondContact O-CG2 3.44Å; C169-I171 PolarHBondContact O-N 2.91Å; I171-F173 VanDerWaalsContact C-N 3.33Å; I171-F173 PolarHBondContact O-N 3.19Å; I171-T174 PolarHBondContact O-N 2.96Å; I171-T174 VanDerWaalsContact O-N 3.17Å; I171-M175 HydrophobicContact CD1-CE 3.98Å; I171-M175 HydrophobicContact CG1-CE 3.88Å; I171-M175 WeakPolarHBondContact O-CG 3.15Å; I171-M175 PolarHBondContact O-N 2.88Å; I171-L478 HydrophobicContact CB-CD1 3.82Å; I171-L478 HydrophobicContact CD1-CD1 4.42Å; I171-L478 HydrophobicContact CG1-CD1 3.92Å; I171-L500 HydrophobicContact CD1-CB 4.32Å; I171-L500 WeakPolarHBondContact CD1-O 3.42Å; I171-M504 HydrophobicContact CD1-CB 3.82Å; I171-M504 HydrophobicContact CD1-CG 3.88Å; I171-D506 WeakPolarHBondContact CG2-OD2 3.38Å; I171-A509 HydrophobicContact CD1-CB 3.81Å; I171-A509 HydrophobicContact CG1-CB 4.1Å; I171-A509 HydrophobicContact CG2-CB 3.65Å
172L91Very high92.2Very high21 Ų2142.5 Ų42.511%0.1121%0.208CC..Hα-helixtrans-61.5-44.8176.9-66.5176.6000111.2I29 I168 C169 T174 M175 W176 F512I29-L172 HydrophobicContact CD1-CD1 3.63Å; I29-L172 HydrophobicContact CG1-CD1 4.28Å; I29-L172 HydrophobicContact CG2-CD1 4.3Å; I168-L172 HydrophobicContact CG2-CD1 4.34Å; I168-L172 WeakPolarHBondContact O-CG 3.34Å; I168-L172 PolarHBondContact O-N 3.46Å; C169-L172 PolarHBondContact O-N 3.32Å; L172-T174 VanDerWaalsContact C-N 3.32Å; L172-T174 PolarHBondContact O-N 3.37Å; L172-M175 PolarHBondContact O-N 3.04Å; L172-W176 WeakPolarHBondContact O-CB 3.42Å; L172-W176 PolarHBondContact O-N 3.33Å; L172-F512 HydrophobicContact CD2-CB 3.47Å; L172-F512 VanDerWaalsContact CD2-CB 3.47Å; L172-F512 HydrophobicContact CD2-CD1 3.8Å; L172-F512 HydrophobicContact CD2-CD2 4.05Å; L172-F512 HydrophobicContact CD2-CG 3.5Å; L172-F512 VanDerWaalsContact CD2-CG 3.5Å
173F93.1Very high92.2Very high109 Ų10953.2 Ų53.248%0.47825%0.249SC..Hα-helixtrans-59.1-44.6174177.7-99.2000111.2C169 I171 M175 W176 M177C169-F173 VanDerWaalsContact O-CB 3.3Å; C169-F173 WeakPolarHBondContact O-CB 3.49Å; C169-F173 PolarHBondContact O-N 2.96Å; I171-F173 VanDerWaalsContact C-N 3.33Å; I171-F173 PolarHBondContact O-N 3.19Å; F173-M175 PolarHBondContact O-N 3.43Å; F173-W176 HydrophobicContact CD2-CE3 4.07Å; F173-W176 HydrophobicContact CD2-CZ3 4.32Å; F173-W176 AromaticContact CE2-CE3 3.94Å; F173-W176 HydrophobicContact CE2-CE3 3.94Å; F173-W176 AromaticContact CE2-CZ3 3.75Å; F173-W176 HydrophobicContact CE2-CZ3 3.75Å; F173-W176 HydrophobicContact CZ-CZ3 4.4Å; F173-W176 PolarHBondContact O-N 3.17Å; F173-M177 HydrophobicContact CE1-CB 4.42Å; F173-M177 HydrophobicContact CE1-SD 4.07Å; F173-M177 VanDerWaalsContact O-CB 3.27Å; F173-M177 WeakPolarHBondContact O-CB 2.95Å; F173-M177 PolarHBondContact O-N 3.4Å
174T94.5Very high92.1Very high0 Ų053.9 Ų53.90%025%0.253CS..Hα-helixtrans-64.4-42.9179.9-57.50000112.1G170 I171 L172 W176 M177 L178 L478 I479G170-T174 WeakPolarHBondContact O-CB 3.36Å; G170-T174 PolarHBondContact O-N 3.38Å; G170-T174 PolarHBondContact O-OG1 2.76Å; I171-T174 PolarHBondContact O-N 2.96Å; I171-T174 VanDerWaalsContact O-N 3.17Å; L172-T174 VanDerWaalsContact C-N 3.32Å; L172-T174 PolarHBondContact O-N 3.37Å; T174-W176 PolarHBondContact O-N 3.47Å; T174-M177 PolarHBondContact O-N 3.02Å; T174-L178 HydrophobicContact CG2-CD1 3.99Å; T174-L178 HydrophobicContact CG2-CG 4.3Å; T174-L178 WeakPolarHBondContact O-CB 3.39Å; T174-L178 VanDerWaalsContact O-CG 3.28Å; T174-L178 WeakPolarHBondContact O-CG 3.43Å; T174-L178 PolarHBondContact O-N 3.36Å; T174-L478 HydrophobicContact CG2-CB 3.63Å; T174-I479 HydrophobicContact CG2-CG1 3.72Å
175M93.9Very high92.2Very high0 Ų057.3 Ų57.30%027%0.272CS..Hα-helixtrans-59.3-48.4175.2-68.9-171.5-17300111.2I171 L172 F173 M177 L178 R179 Y493 C497 L500 A501 A509 F512 A513I171-M175 HydrophobicContact CD1-CE 3.98Å; I171-M175 HydrophobicContact CG1-CE 3.88Å; I171-M175 WeakPolarHBondContact O-CG 3.15Å; I171-M175 PolarHBondContact O-N 2.88Å; L172-M175 PolarHBondContact O-N 3.04Å; F173-M175 PolarHBondContact O-N 3.43Å; M175-M177 PolarHBondContact O-N 3.43Å; M175-L178 PolarHBondContact O-N 2.87Å; M175-R179 PolarHBondContact O-N 3.09Å; M175-R179 VanDerWaalsContact O-N 3.09Å; M175-Y493 PolarHBondContact O-OH 2.99Å; M175-Y493 VanDerWaalsContact O-OH 3.04Å; M175-C497 HydrophobicContact CE-CB 4.21Å; M175-C497 WeakPolarHBondContact CE-O 3.4Å; M175-C497 HydrophobicContact SD-CB 3.83Å; M175-L500 HydrophobicContact CE-CB 4.23Å; M175-L500 HydrophobicContact CG-CD1 4.45Å; M175-A501 HydrophobicContact CE-CB 3.86Å; M175-A509 HydrophobicContact CE-CB 3.98Å; M175-F512 HydrophobicContact CB-CE1 4.17Å; M175-F512 HydrophobicContact SD-CD1 3.86Å; M175-F512 HydrophobicContact SD-CE1 4.24Å; M175-A513 HydrophobicContact SD-CB 4.38Å
176W93.6Very high92.4Very high140 Ų14055.9 Ų55.953%0.5326%0.263SS..Hα-helixtrans-59.6-45.1176.2172.782.7000112L172 F173 T174 L178 R179 V180L172-W176 WeakPolarHBondContact O-CB 3.42Å; L172-W176 PolarHBondContact O-N 3.33Å; F173-W176 HydrophobicContact CD2-CE3 4.07Å; F173-W176 HydrophobicContact CD2-CZ3 4.32Å; F173-W176 AromaticContact CE2-CE3 3.94Å; F173-W176 HydrophobicContact CE2-CE3 3.94Å; F173-W176 AromaticContact CE2-CZ3 3.75Å; F173-W176 HydrophobicContact CE2-CZ3 3.75Å; F173-W176 HydrophobicContact CZ-CZ3 4.4Å; F173-W176 PolarHBondContact O-N 3.17Å; T174-W176 PolarHBondContact O-N 3.47Å; W176-L178 PolarHBondContact O-N 3.04Å; W176-R179 VanDerWaalsContact O-CB 3.26Å; W176-R179 WeakPolarHBondContact O-CB 3.29Å; W176-R179 PolarHBondContact O-N 3.46Å; W176-V180 HydrophobicContact CD2-CG2 4.3Å; W176-V180 HydrophobicContact CH2-CG2 4.48Å; W176-V180 HydrophobicContact CZ2-CG2 3.94Å; W176-V180 WeakPolarHBondContact O-CG2 3.47Å; W176-V180 PolarHBondContact O-N 3.42Å; W176-V180 VanDerWaalsContact O-N 3.1Å
177M95.2Very high92.5Very high34 Ų3456.4 Ų56.417%0.16727%0.267CS..Hα-helixtrans-62.5-44.8-179.8-169.7-167.974.600111.4F173 T174 M175 R179 V180 I181 I479F173-M177 HydrophobicContact CE1-CB 4.42Å; F173-M177 HydrophobicContact CE1-SD 4.07Å; F173-M177 VanDerWaalsContact O-CB 3.27Å; F173-M177 WeakPolarHBondContact O-CB 2.95Å; F173-M177 PolarHBondContact O-N 3.4Å; T174-M177 PolarHBondContact O-N 3.02Å; M175-M177 PolarHBondContact O-N 3.43Å; M177-R179 VanDerWaalsContact C-N 3.28Å; M177-R179 PolarHBondContact O-N 3.39Å; M177-V180 PolarHBondContact O-N 2.93Å; M177-V180 VanDerWaalsContact O-N 3.15Å; M177-I181 HydrophobicContact CE-CD1 3.7Å; M177-I181 HydrophobicContact CG-CD1 3.73Å; M177-I181 HydrophobicContact CG-CG1 4.29Å; M177-I181 WeakPolarHBondContact O-CB 3.38Å; M177-I181 WeakPolarHBondContact O-CG1 3.5Å; M177-I181 PolarHBondContact O-N 3.19Å; M177-I181 HydrophobicContact SD-CD1 4.09Å; M177-I479 HydrophobicContact CE-CB 4.15Å; M177-I479 HydrophobicContact CE-CD1 3.69Å; M177-I479 HydrophobicContact CE-CG1 3.53Å; M177-I479 HydrophobicContact CE-CG2 3.64Å; M177-I479 HydrophobicContact SD-CD1 4.25Å
178L94.9Very high92.5Very high1 Ų159.2 Ų59.21%0.00528%0.284CS..Hα-helixtrans-60.3-39175.9-70.9168.8000111.6T174 M175 W176 V180 F182 I483 Y493 M496 L500T174-L178 HydrophobicContact CG2-CD1 3.99Å; T174-L178 HydrophobicContact CG2-CG 4.3Å; T174-L178 WeakPolarHBondContact O-CB 3.39Å; T174-L178 VanDerWaalsContact O-CG 3.28Å; T174-L178 WeakPolarHBondContact O-CG 3.43Å; T174-L178 PolarHBondContact O-N 3.36Å; M175-L178 PolarHBondContact O-N 2.87Å; W176-L178 PolarHBondContact O-N 3.04Å; L178-V180 VanDerWaalsContact C-N 3.33Å; L178-V180 PolarHBondContact O-N 3.17Å; L178-F182 HydrophobicContact CD2-CD2 4.3Å; L178-F182 HydrophobicContact CD2-CE2 3.85Å; L178-F182 WeakPolarHBondContact O-CD2 3.28Å; L178-F182 PolarHBondContact O-N 3.4Å; L178-I483 HydrophobicContact CD2-CG1 3.93Å; L178-Y493 HydrophobicContact CB-CE2 4.43Å; L178-M496 HydrophobicContact CD1-CE 4.02Å; L178-L500 HydrophobicContact CD1-CD1 3.62Å
179R94.3Very high92.8Very high101 Ų10159.4 Ų59.438%0.38128%0.284SS..Hα-helixtrans-58.9-45.1174.6-168.4-173169.5172.3-4.1111.7M175 W176 M177 R183 V184 Y493M175-R179 PolarHBondContact O-N 3.09Å; M175-R179 VanDerWaalsContact O-N 3.09Å; W176-R179 VanDerWaalsContact O-CB 3.26Å; W176-R179 WeakPolarHBondContact O-CB 3.29Å; W176-R179 PolarHBondContact O-N 3.46Å; M177-R179 VanDerWaalsContact C-N 3.28Å; M177-R179 PolarHBondContact O-N 3.39Å; R179-R183 WeakPolarHBondContact O-CA 3.17Å; R179-R183 PolarHBondContact O-N 2.9Å; R179-R183 VanDerWaalsContact O-N 3.1Å; R179-V184 HydrophobicContact CG-CB 4.01Å; R179-V184 PolarHBondContact O-N 2.91Å; R179-Y493 HydrophobicContact CB-CE1 4.4Å; R179-Y493 HydrophobicContact CB-CE2 3.86Å; R179-Y493 HydrophobicContact CG-CE1 4.26Å; R179-Y493 HydrophobicContact CG-CE2 4.49Å
180V95.2Very high92.6Very high81 Ų8155.7 Ų55.749%0.49126%0.26SS..Hα-helixtrans-69.8-49.2-178.6175.20000110.8W176 M177 L178 F182 R183W176-V180 HydrophobicContact CD2-CG2 4.3Å; W176-V180 HydrophobicContact CH2-CG2 4.48Å; W176-V180 HydrophobicContact CZ2-CG2 3.94Å; W176-V180 WeakPolarHBondContact O-CG2 3.47Å; W176-V180 PolarHBondContact O-N 3.42Å; W176-V180 VanDerWaalsContact O-N 3.1Å; M177-V180 PolarHBondContact O-N 2.93Å; M177-V180 VanDerWaalsContact O-N 3.15Å; L178-V180 VanDerWaalsContact C-N 3.33Å; L178-V180 PolarHBondContact O-N 3.17Å; V180-F182 VanDerWaalsContact C-N 3.34Å; V180-F182 PolarHBondContact O-N 3.19Å; V180-R183 PolarHBondContact O-N 2.9Å; V180-R183 VanDerWaalsContact O-N 3.13Å
181I95Very high92Very high89 Ų8960.5 Ų60.546%0.45628%0.278SS..Hα-helixtrans-57.6-46.9-179-71.3172000111M177 R183M177-I181 HydrophobicContact CE-CD1 3.7Å; M177-I181 HydrophobicContact CG-CD1 3.73Å; M177-I181 HydrophobicContact CG-CG1 4.29Å; M177-I181 WeakPolarHBondContact O-CB 3.38Å; M177-I181 WeakPolarHBondContact O-CG1 3.5Å; M177-I181 PolarHBondContact O-N 3.19Å; M177-I181 HydrophobicContact SD-CD1 4.09Å; I181-R183 VanDerWaalsContact C-N 3.31Å; I181-R183 PolarHBondContact O-N 3.13Å
182F94.7Very high91.6Very high57 Ų5765.1 Ų65.125%0.2530%0.299CS..THydrogen-bonded Turntrans-90.27.9-178.3-66.5-70.5000113.8L178 V180 V184 I483 R486 M487L178-F182 HydrophobicContact CD2-CD2 4.3Å; L178-F182 HydrophobicContact CD2-CE2 3.85Å; L178-F182 WeakPolarHBondContact O-CD2 3.28Å; L178-F182 PolarHBondContact O-N 3.4Å; V180-F182 VanDerWaalsContact C-N 3.34Å; V180-F182 PolarHBondContact O-N 3.19Å; F182-V184 HydrophobicContact CB-CG2 3.76Å; F182-V184 PolarHBondContact O-N 3.38Å; F182-I483 HydrophobicContact CE2-CG1 4.24Å; F182-I483 HydrophobicContact CZ-CB 4.44Å; F182-I483 HydrophobicContact CZ-CG1 4.31Å; F182-I483 HydrophobicContact CZ-CG2 4.28Å; F182-R486 HydrophobicContact CB-CG 4.47Å; F182-R486 HydrophobicContact CD1-CB 4.49Å; F182-R486 HydrophobicContact CD1-CG 3.63Å; F182-R486 HydrophobicContact CD2-CB 4.17Å; F182-R486 HydrophobicContact CD2-CG 3.79Å; F182-R486 HydrophobicContact CE1-CB 4.08Å; F182-R486 HydrophobicContact CE1-CG 3.66Å; F182-R486 HydrophobicContact CE2-CB 3.74Å; F182-R486 HydrophobicContact CE2-CG 3.82Å; F182-R486 HydrophobicContact CG-CG 3.7Å; F182-R486 HydrophobicContact CZ-CB 3.69Å; F182-R486 HydrophobicContact CZ-CG 3.75Å; F182-M487 HydrophobicContact CE1-CG 4.12Å; F182-M487 HydrophobicContact CZ-CG 4.19Å
183R92.7Very high90.7Very high230 Ų23065.1 Ų65.187%0.86830%0.299SS*.THydrogen-bonded Turntrans46.548.8179.2-59.6-177.4-179.3178.7-0.2112.4R179 V180 I181 N185R179-R183 WeakPolarHBondContact O-CA 3.17Å; R179-R183 PolarHBondContact O-N 2.9Å; R179-R183 VanDerWaalsContact O-N 3.1Å; V180-R183 PolarHBondContact O-N 2.9Å; V180-R183 VanDerWaalsContact O-N 3.13Å; I181-R183 VanDerWaalsContact C-N 3.31Å; I181-R183 PolarHBondContact O-N 3.13Å; R183-N185 PolarHBondContact O-N 2.75Å
184V91.9Very high89.6Confident13 Ų1365.5 Ų65.58%0.07930%0.302CS..  trans-75.8125.2-170.1178.40000111.3R179 F182 E189 Y493R179-V184 HydrophobicContact CG-CB 4.01Å; R179-V184 PolarHBondContact O-N 2.91Å; F182-V184 HydrophobicContact CB-CG2 3.76Å; F182-V184 PolarHBondContact O-N 3.38Å; V184-E189 HydrophobicContact CG1-CG 3.5Å; V184-E189 VanDerWaalsContact CG1-CG 3.5Å; V184-Y493 HydrophobicContact CB-CG 4.28Å; V184-Y493 HydrophobicContact CG1-CD1 3.74Å; V184-Y493 HydrophobicContact CG1-CD2 4.43Å; V184-Y493 HydrophobicContact CG1-CG 3.69Å; V184-Y493 HydrophobicContact CG2-CD2 4.15Å; V184-Y493 HydrophobicContact CG2-CG 4.17Å
185N92.6Very high88.2Confident94 Ų9468.2 Ų68.250%0.50332%0.321SS..  trans-89.4114.7163.3-172.4-33.1000109.5R183 E187 T188 E189R183-N185 PolarHBondContact O-N 2.75Å; N185-E187 VanDerWaalsContact C-N 3.33Å; N185-E187 PolarHBondContact O-N 3.28Å; N185-E187 WeakPolarHBondContact OD1-CB 3.39Å; N185-E187 PolarHBondContact OD1-N 2.84Å; N185-T188 PolarHBondContact O-N 2.96Å; N185-T188 PolarHBondContact OD1-N 3.41Å; N185-E189 WeakPolarHBondContact O-CG 3.47Å; N185-E189 PolarHBondContact O-N 3.41Å; N185-E189 VanDerWaalsContact O-N 3.09Å
186V91.3Very high86.7Confident12 Ų1271.9 Ų71.97%0.07335%0.347CS..Hα-helixtrans-64.1-37.4-175.3174.40000112.2E189 A190 Y493 L494 L516 H517V186-E189 PolarHBondContact O-N 2.88Å; V186-A190 PolarHBondContact O-N 3.4Å; V186-Y493 HydrophobicContact CG2-CE1 4.35Å; V186-L494 HydrophobicContact CG1-CD2 4.11Å; V186-L516 HydrophobicContact CG1-CB 4.36Å; V186-L516 WeakPolarHBondContact CG1-O 3.34Å; V186-H517 HydrophobicContact CG1-CB 3.95Å
187E90.1Very high84.9Confident99 Ų9969.2 Ų69.246%0.46334%0.337SS..Hα-helixtrans-67.3-43.5-179.2-164.162.8-155.100110.9N185 E189 A190 Q191 H517N185-E187 VanDerWaalsContact C-N 3.33Å; N185-E187 PolarHBondContact O-N 3.28Å; N185-E187 WeakPolarHBondContact OD1-CB 3.39Å; N185-E187 PolarHBondContact OD1-N 2.84Å; E187-E189 VanDerWaalsContact C-N 3.34Å; E187-E189 PolarHBondContact O-N 3.09Å; E187-A190 WeakPolarHBondContact O-CB 3.49Å; E187-A190 PolarHBondContact O-N 3.13Å; E187-Q191 WeakPolarHBondContact O-CG 3.33Å; E187-Q191 PolarHBondContact O-N 2.85Å; E187-H517 IonicContact OE1-NE2 3.53Å; E187-H517 IonicContact OE2-CD2 3.36Å; E187-H517 IonicContact OE2-NE2 3.17Å; E187-H517 PolarHBondContact OE2-NE2 3.34Å
188T90.1Very high82.5Confident62 Ų6269.9 Ų69.938%0.3834%0.343SS..Hα-helixtrans-63.6-41.4176.6-48.30000111.5N185 A190 Q191 Q192N185-T188 PolarHBondContact O-N 2.96Å; N185-T188 PolarHBondContact OD1-N 3.41Å; T188-A190 VanDerWaalsContact C-N 3.34Å; T188-Q191 PolarHBondContact O-N 2.86Å; T188-Q192 WeakPolarHBondContact O-CB 3.49Å; T188-Q192 WeakPolarHBondContact O-CG 3.41Å; T188-Q192 PolarHBondContact O-N 3.39Å
189E91.3Very high79.7Confident10 Ų1077 Ų775%0.04738%0.381CS..Hα-helixtrans-65-37.8175-68.2-79.9163.200111.6V184 N185 V186 E187 Q192 H193 R486 N492 Y493V184-E189 HydrophobicContact CG1-CG 3.5Å; V184-E189 VanDerWaalsContact CG1-CG 3.5Å; N185-E189 WeakPolarHBondContact O-CG 3.47Å; N185-E189 PolarHBondContact O-N 3.41Å; N185-E189 VanDerWaalsContact O-N 3.09Å; V186-E189 PolarHBondContact O-N 2.88Å; E187-E189 VanDerWaalsContact C-N 3.34Å; E187-E189 PolarHBondContact O-N 3.09Å; E189-Q192 PolarHBondContact O-N 3Å; E189-H193 WeakPolarHBondContact O-CB 3.28Å; E189-H193 PolarHBondContact O-N 3.17Å; E189-R486 IonicContact OE1-CZ 3.52Å; E189-R486 IonicContact OE1-NH1 3.6Å; E189-R486 PolarHBondContact OE1-NH1 3.23Å; E189-R486 IonicContact OE1-NH2 2.68Å; E189-R486 PolarHBondContact OE1-NH2 3.48Å; E189-R486 IonicContact OE2-NH1 3.19Å; E189-R486 PolarHBondContact OE2-NH1 2.91Å; E189-N492 PolarHBondContact O-ND2 2.92Å; E189-N492 WeakPolarHBondContact OE2-CA 3.45Å; E189-N492 PolarHBondContact OE2-ND2 2.83Å; E189-Y493 PolarHBondContact OE2-N 3.14Å
190A84.6Confident77Confident2 Ų275.7 Ų75.72%0.01740%0.399CS..Hα-helixtrans-62.2-46.5176.100000111.3V186 E187 T188 Q192 H193 E194 L494 H517V186-A190 PolarHBondContact O-N 3.4Å; E187-A190 WeakPolarHBondContact O-CB 3.49Å; E187-A190 PolarHBondContact O-N 3.13Å; T188-A190 VanDerWaalsContact C-N 3.34Å; A190-Q192 VanDerWaalsContact C-N 3.35Å; A190-Q192 PolarHBondContact O-N 3.38Å; A190-H193 PolarHBondContact O-N 3.39Å; A190-E194 PolarHBondContact O-N 3.4Å; A190-L494 HydrophobicContact CB-CD1 4.01Å; A190-H517 VanDerWaalsContact CB-CD2 3.41Å; A190-H517 WeakPolarHBondContact CB-CD2 3.31Å; A190-H517 VanDerWaalsContact CB-NE2 3.35Å; A190-H517 WeakPolarHBondContact CB-NE2 3.46Å
191Q80.7Confident74.5Confident116 Ų11674.1 Ų74.154%0.54240%0.399SS..Hα-helixtrans-62.7-40175.6-68.2174.71.100112.3E187 T188 E194 S195E187-Q191 WeakPolarHBondContact O-CG 3.33Å; E187-Q191 PolarHBondContact O-N 2.85Å; T188-Q191 PolarHBondContact O-N 2.86Å; Q191-E194 PolarHBondContact O-N 3.2Å; Q191-S195 WeakPolarHBondContact O-CB 3.35Å; Q191-S195 PolarHBondContact O-N 3.17Å; Q191-S195 PolarHBondContact O-OG 3.18Å
192Q82.2Confident72.2Confident96 Ų9670.4 Ų70.445%0.44938%0.382SS..Hα-helixtrans-64.1-39.5174.5-79-180-1.500112.2T188 E189 A190 S195 S196T188-Q192 WeakPolarHBondContact O-CB 3.49Å; T188-Q192 WeakPolarHBondContact O-CG 3.41Å; T188-Q192 PolarHBondContact O-N 3.39Å; E189-Q192 PolarHBondContact O-N 3Å; A190-Q192 VanDerWaalsContact C-N 3.35Å; A190-Q192 PolarHBondContact O-N 3.38Å; Q192-S195 VanDerWaalsContact CA-OG 3.28Å; Q192-S195 WeakPolarHBondContact CA-OG 3.41Å; Q192-S195 PolarHBondContact O-OG 3.47Å; Q192-S196 VanDerWaalsContact O-CB 3.23Å; Q192-S196 WeakPolarHBondContact O-CB 3.44Å; Q192-S196 PolarHBondContact O-N 2.96Å; Q192-S196 PolarHBondContact O-OG 2.85Å
193H73.9Confident70.6Confident22 Ų2271.6 Ų71.610%0.10239%0.39CS..Hα-helixtrans-66.3-40.4176.6-175.9-91.8000111.2E189 A190 S196 R197 T495 A522E189-H193 WeakPolarHBondContact O-CB 3.28Å; E189-H193 PolarHBondContact O-N 3.17Å; A190-H193 PolarHBondContact O-N 3.39Å; H193-S196 PolarHBondContact O-N 3.11Å; H193-R197 WeakPolarHBondContact O-CB 3.18Å; H193-R197 PolarHBondContact O-N 3.1Å; H193-T495 PolarHBondContact CD2-OG1 2.95Å; H193-A522 VanDerWaalsContact CD2-CB 3.48Å; H193-A522 WeakPolarHBondContact CD2-CB 3.28Å; H193-A522 VanDerWaalsContact CE1-CB 3.48Å; H193-A522 WeakPolarHBondContact CE1-CB 3.49Å; H193-A522 WeakPolarHBondContact NE2-CB 3.22Å
194E68.5Low69.8Low117 Ų11761.5 Ų61.555%0.54735%0.353SS..Hα-helixtrans-69.3-40.7179.3-165.1157.2-162.400112.7A190 Q191 R197 T198A190-E194 PolarHBondContact O-N 3.4Å; Q191-E194 PolarHBondContact O-N 3.2Å; E194-R197 WeakPolarHBondContact O-CB 3.35Å; E194-R197 PolarHBondContact O-N 3.15Å; E194-T198 PolarHBondContact O-N 3.43Å; E194-T198 PolarHBondContact O-OG1 3.4Å
195S65.8Low69.5Low57 Ų5766.2 Ų66.240%0.39937%0.373SS..Hα-helixtrans-66.9-36.4171.3500000112.9Q191 Q192 T198 N199Q191-S195 WeakPolarHBondContact O-CB 3.35Å; Q191-S195 PolarHBondContact O-N 3.17Å; Q191-S195 PolarHBondContact O-OG 3.18Å; Q192-S195 VanDerWaalsContact CA-OG 3.28Å; Q192-S195 WeakPolarHBondContact CA-OG 3.41Å; Q192-S195 PolarHBondContact O-OG 3.47Å; S195-T198 VanDerWaalsContact C-OG1 3.31Å; S195-T198 WeakPolarHBondContact CA-OG1 3.43Å; S195-T198 PolarHBondContact O-N 3.22Å; S195-T198 PolarHBondContact O-OG1 3.36Å; S195-N199 PolarHBondContact O-N 2.86Å
196S63.3Low69.3Low77 Ų7764.2 Ų64.254%0.53836%0.364SS..Hα-helixtrans-69.5-34.5173.9-59.20000111.9Q192 H193 N199 G200Q192-S196 VanDerWaalsContact O-CB 3.23Å; Q192-S196 WeakPolarHBondContact O-CB 3.44Å; Q192-S196 PolarHBondContact O-N 2.96Å; Q192-S196 PolarHBondContact O-OG 2.85Å; H193-S196 PolarHBondContact O-N 3.11Å; S196-N199 PolarHBondContact O-N 2.91Å; S196-G200 PolarHBondContact O-N 2.89Å
197R55.8Low69.4Low83 Ų8364.5 Ų64.531%0.31337%0.365SS..Hα-helixtrans-64.6-43.6173.3-111.5176.9162.7176.9-7.2111.8H193 E194 N199 G200 G201 A202 S520H193-R197 WeakPolarHBondContact O-CB 3.18Å; H193-R197 PolarHBondContact O-N 3.1Å; E194-R197 WeakPolarHBondContact O-CB 3.35Å; E194-R197 PolarHBondContact O-N 3.15Å; R197-N199 PolarHBondContact O-N 3.49Å; R197-G200 PolarHBondContact O-N 3.34Å; R197-G201 CarbonylContact O-C 3.13Å; R197-G201 PolarHBondContact O-N 3.32Å; R197-G201 VanDerWaalsContact O-N 3.09Å; R197-A202 WeakPolarHBondContact O-CA 3.42Å; R197-A202 PolarHBondContact O-N 2.8Å; R197-S520 PolarHBondContact NH1-O 3.44Å
198T43.4Very low69.6Low48 Ų4860.9 Ų60.929%0.29435%0.349SS..Hα-helixtrans-63.3-24.917635.80000112.5E194 S195 A202E194-T198 PolarHBondContact O-N 3.43Å; E194-T198 PolarHBondContact O-OG1 3.4Å; S195-T198 VanDerWaalsContact C-OG1 3.31Å; S195-T198 WeakPolarHBondContact CA-OG1 3.43Å; S195-T198 PolarHBondContact O-N 3.22Å; S195-T198 PolarHBondContact O-OG1 3.36Å; T198-A202 WeakPolarHBondContact O-CB 3.44Å
199N37.6Very low69.8Low151 Ų15158 Ų5881%0.80733%0.331SS*.Hα-helixtrans-94.1-22.8175.7-75.2-16.4000115.6S195 S196 R197S195-N199 PolarHBondContact O-N 2.86Å; S196-N199 PolarHBondContact O-N 2.91Å; R197-N199 PolarHBondContact O-N 3.49Å
200G36.2Very low70Confident74 Ų7461.8 Ų61.876%0.76335%0.345SS*.Hα-helixtrans-122.8-1.6-169.400000116.9S196 R197S196-G200 PolarHBondContact O-N 2.89Å; R197-G200 PolarHBondContact O-N 3.34Å
201G43Very low70.6Confident48 Ų4861.7 Ų61.750%0.49534%0.344SS..SBendtrans-179.963.8-179.900000107.3R197 L203R197-G201 CarbonylContact O-C 3.13Å; R197-G201 PolarHBondContact O-N 3.32Å; R197-G201 VanDerWaalsContact O-N 3.09Å; G201-L203 PolarHBondContact O-N 3.46Å
202A47.1Very low71.3Confident11 Ų1160.3 Ų60.39%0.09134%0.338CS..  trans-64.7126.3-159.500000110.7R197 T198 I204 Q263 P264R197-A202 WeakPolarHBondContact O-CA 3.42Å; R197-A202 PolarHBondContact O-N 2.8Å; T198-A202 WeakPolarHBondContact O-CB 3.44Å; A202-I204 PolarHBondContact O-N 2.96Å; A202-I204 VanDerWaalsContact O-N 3.17Å; A202-Q263 HydrophobicContact CB-CB 4.32Å; A202-P264 HydrophobicContact CB-CG 3.71Å
203L61.7Low71.9Confident82 Ų8257.7 Ų57.743%0.42933%0.327SS..  trans-45.4126.2169-76.2160.7000107.9G201 K205G201-L203 PolarHBondContact O-N 3.46Å; L203-K205 PolarHBondContact O-N 2.8Å
204I75Confident72.9Confident17 Ų1760.9 Ų60.99%0.08735%0.35CS..  trans-52.4111.8175.3-57.3-71.6000107.2A202 V261 R321 E328 V330A202-I204 PolarHBondContact O-N 2.96Å; A202-I204 VanDerWaalsContact O-N 3.17Å; I204-V261 HydrophobicContact CG2-CG1 3.35Å; I204-R321 HydrophobicContact CG2-CG 4.25Å; I204-E328 HydrophobicContact CG1-CG 4.46Å; I204-V330 HydrophobicContact CD1-CB 4.1Å; I204-V330 HydrophobicContact CD1-CG2 3.22Å
205K84.6Confident74.1Confident112 Ų11261.5 Ų61.549%0.48736%0.357SS..EExtended strand (participates in β ladder)trans-98.4168.6176.5-79-162.4179.9-175.30109.6L203 V261 G262 P264 L267L203-K205 PolarHBondContact O-N 2.8Å; K205-V261 WeakPolarHBondContact O-CA 3.39Å; K205-G262 PolarHBondContact N-O 3.26Å; K205-G262 PolarHBondContact O-N 3.39Å; K205-G262 VanDerWaalsContact O-N 3.1Å; K205-P264 HydrophobicContact CD-CG 4.1Å; K205-P264 HydrophobicContact CG-CG 4.23Å; K205-L267 HydrophobicContact CB-CD1 3.81Å
206T89.5Confident75.4Confident53 Ų5359.4 Ų59.433%0.32534%0.341SS..EExtended strand (participates in β ladder)trans-131.4138.7171.858.80000109.6H259 L260 V261T206-H259 WeakPolarHBondContact CB-NE2 3.38Å; T206-L260 WeakPolarHBondContact CA-O 3.24Å; T206-V261 HydrophobicContact CG2-CB 4.27Å; T206-V261 HydrophobicContact CG2-CG1 4.07Å; T206-V261 HydrophobicContact CG2-CG2 3.83Å
207I92.2Very high76.8Confident18 Ų1859.3 Ų59.39%0.09233%0.332CS..EExtended strand (participates in β ladder)trans-131.8154.7173.361.2172.2000109.4I209 L260 L267 E277I207-I209 HydrophobicContact CD1-CD1 3.41Å; I207-I209 VanDerWaalsContact CD1-CD1 3.41Å; I207-I209 HydrophobicContact CD1-CG1 3.75Å; I207-I209 HydrophobicContact CG1-CD1 4.16Å; I207-I209 HydrophobicContact CG1-CG1 4.22Å; I207-L260 HydrophobicContact CG1-CB 4.23Å; I207-L260 PolarHBondContact N-O 3.21Å; I207-L260 VanDerWaalsContact N-O 3.1Å; I207-L260 PolarHBondContact O-N 2.97Å; I207-L267 HydrophobicContact CD1-CB 3.77Å; I207-L267 HydrophobicContact CD1-CD2 4.28Å; I207-L267 HydrophobicContact CD1-CG 4.45Å; I207-L267 HydrophobicContact CG1-CB 4.23Å; I207-L267 HydrophobicContact CG1-CD1 4.29Å; I207-L267 HydrophobicContact CG1-CD2 4.03Å; I207-L267 HydrophobicContact CG1-CG 4.4Å; I207-L267 HydrophobicContact CG2-CD1 4.27Å; I207-E277 HydrophobicContact CB-CG 4.42Å; I207-E277 VanDerWaalsContact CG2-OE1 3.31Å; I207-E277 WeakPolarHBondContact CG2-OE1 3.41Å
208N94.9Very high78.6Confident23 Ų2360.3 Ų60.312%0.12334%0.343CS..EExtended strand (participates in β ladder)trans-106125168-53.4-55.1000108L258 H259 E277 V278 T280 L282N208-L258 CarbonylContact C-O 3.59Å; N208-L258 VanDerWaalsContact CA-O 3.29Å; N208-L258 WeakPolarHBondContact CA-O 3.09Å; N208-H259 PolarHBondContact OD1-ND1 3.08Å; N208-E277 CarbonylContact O-C 3.58Å; N208-E277 WeakPolarHBondContact O-CA 3.35Å; N208-V278 HydrophobicContact CB-CG2 3.99Å; N208-V278 WeakPolarHBondContact CB-O 3.33Å; N208-V278 PolarHBondContact O-N 3Å; N208-T280 PolarHBondContact ND2-O 2.71Å; N208-L282 HydrophobicContact CB-CD1 4.13Å
209I94.8Very high81.1Confident0 Ų061.1 Ų61.10%035%0.346CS..EExtended strand (participates in β ladder)trans-114.8132.2176.7-68.9165000109I207 L257 L258 L260 A270 Q271 I274 Q276I207-I209 HydrophobicContact CD1-CD1 3.41Å; I207-I209 VanDerWaalsContact CD1-CD1 3.41Å; I207-I209 HydrophobicContact CD1-CG1 3.75Å; I207-I209 HydrophobicContact CG1-CD1 4.16Å; I207-I209 HydrophobicContact CG1-CG1 4.22Å; I209-L257 CarbonylContact O-C 3.16Å; I209-L257 WeakPolarHBondContact O-CA 3.43Å; I209-L258 PolarHBondContact N-O 3.09Å; I209-L258 PolarHBondContact O-N 3.34Å; I209-L260 HydrophobicContact CD1-CD1 3.74Å; I209-A270 HydrophobicContact CD1-CB 4.3Å; I209-Q271 HydrophobicContact CD1-CB 3.99Å; I209-I274 HydrophobicContact CG2-CB 3.95Å; I209-I274 HydrophobicContact CG2-CG2 3.63Å; I209-Q276 CarbonylContact C-O 3.19Å; I209-Q276 WeakPolarHBondContact CA-O 3.28Å
210R96Very high83.8Confident90 Ų9054.2 Ų54.234%0.3431%0.309SS..EExtended strand (participates in β ladder)trans-81.2129.8163.8-175.5-177.1-64.5142.5-1.2109.3E212 D256 L257 G275 Q276 V278R210-E212 HydrophobicContact CB-CG 4.48Å; R210-E212 HydrophobicContact CG-CG 4.11Å; R210-E212 IonicContact NH1-OE1 2.8Å; R210-E212 PolarHBondContact O-N 3.05Å; R210-D256 CarbonylContact C-O 3.35Å; R210-D256 WeakPolarHBondContact CA-O 3.49Å; R210-L257 HydrophobicContact CB-CD2 3.6Å; R210-L257 HydrophobicContact CG-CD2 3.84Å; R210-G275 WeakPolarHBondContact O-CA 3.41Å; R210-Q276 PolarHBondContact N-O 2.88Å; R210-Q276 PolarHBondContact O-N 3.4Å; R210-V278 HydrophobicContact CB-CG1 3.93Å
211V96.5Very high86.4Confident1 Ų150.9 Ų50.91%0.00627%0.274CS..EExtended strand (participates in β ladder)trans-71.5110.9174.6-177.80000108.9L216 I252 G255 D256 L258 I274V211-L216 HydrophobicContact CG1-CB 4.38Å; V211-I252 HydrophobicContact CB-CG2 4.28Å; V211-I252 HydrophobicContact CG1-CG2 3.75Å; V211-I252 HydrophobicContact CG2-CG2 3.81Å; V211-G255 PolarHBondContact O-N 3.36Å; V211-D256 HydrophobicContact CB-CB 4.39Å; V211-D256 HydrophobicContact CG2-CB 3.95Å; V211-D256 WeakPolarHBondContact CG2-O 3.36Å; V211-D256 PolarHBondContact N-O 3.48Å; V211-L258 HydrophobicContact CG2-CD1 3.89Å; V211-L258 HydrophobicContact CG2-CG 3.96Å; V211-I274 HydrophobicContact CB-CG2 4.4Å; V211-I274 HydrophobicContact CG2-CG2 3.85Å
212E95.6Very high88.6Confident87 Ų8752.6 Ų52.641%0.40727%0.268SS..  trans-120.6-14.7178.3-66.3-174.9168.300112.1R210 P214 I274R210-E212 HydrophobicContact CB-CG 4.48Å; R210-E212 HydrophobicContact CG-CG 4.11Å; R210-E212 IonicContact NH1-OE1 2.8Å; R210-E212 PolarHBondContact O-N 3.05Å; E212-P214 WeakPolarHBondContact O-CD 3.47Å; E212-I274 PolarHBondContact N-O 3.43Å
213N95.1Very high90.8Very high40 Ų4056.5 Ų56.521%0.21429%0.287CS..  trans-72.4114176.5-175-9.7000111.1N215 L216 V273 I274N213-N215 PolarHBondContact O-N 3.32Å; N213-N215 WeakPolarHBondContact OD1-CB 2.98Å; N213-N215 PolarHBondContact OD1-N 3.01Å; N213-N215 PolarHBondContact OD1-ND2 3.48Å; N213-L216 HydrophobicContact CB-CD1 4.13Å; N213-L216 HydrophobicContact CB-CG 4.08Å; N213-L216 PolarHBondContact O-N 3.14Å; N213-L216 VanDerWaalsContact O-N 3.11Å; N213-V273 VanDerWaalsContact CB-O 3.31Å; N213-V273 WeakPolarHBondContact CB-O 3.32Å; N213-V273 PolarHBondContact ND2-O 3.45Å; N213-I274 WeakPolarHBondContact CB-O 3.44Å; N213-I274 PolarHBondContact N-O 2.85Å
214P94Very high92.2Very high90 Ų9052.7 Ų52.758%0.58427%0.268SS*.G310 helixtrans-64.4-24.2-179.1-20.334.1000113.6E212 L216 H217E212-P214 WeakPolarHBondContact O-CD 3.47Å; P214-L216 PolarHBondContact O-N 3.37Å; P214-H217 WeakPolarHBondContact O-CB 3.26Å; P214-H217 PolarHBondContact O-N 3.47Å; P214-H217 VanDerWaalsContact O-N 3.1Å
215N94.1Very high92.9Very high130 Ų13057.3 Ų57.370%0.69530%0.298SS*.G310 helixtrans-68.9-16.1178.1-58.9-66.2000112.9N213 L219N213-N215 PolarHBondContact O-N 3.32Å; N213-N215 WeakPolarHBondContact OD1-CB 2.98Å; N213-N215 PolarHBondContact OD1-N 3.01Å; N213-N215 PolarHBondContact OD1-ND2 3.48Å; N215-L219 WeakPolarHBondContact O-CD1 3.42Å
216L93.5Very high93.1Very high12 Ų1253.8 Ų53.86%0.06328%0.284CS..G310 helixtrans-90.6-7.6175.7-56.6-176.7000112.5V211 N213 P214 L219 V224 I274V211-L216 HydrophobicContact CG1-CB 4.38Å; N213-L216 HydrophobicContact CB-CD1 4.13Å; N213-L216 HydrophobicContact CB-CG 4.08Å; N213-L216 PolarHBondContact O-N 3.14Å; N213-L216 VanDerWaalsContact O-N 3.11Å; P214-L216 PolarHBondContact O-N 3.37Å; L216-L219 HydrophobicContact CD2-CD1 4.4Å; L216-L219 PolarHBondContact O-N 3.48Å; L216-V224 HydrophobicContact CD2-CG1 3.99Å; L216-V224 HydrophobicContact CD2-CG2 3.92Å; L216-I274 HydrophobicContact CD1-CB 4.11Å; L216-I274 HydrophobicContact CD1-CG1 3.91Å; L216-I274 HydrophobicContact CD1-CG2 4.11Å
217H92.8Very high93.1Very high76 Ų7651.8 Ų51.835%0.35227%0.272SS..THydrogen-bonded Turntrans-64.5136.5177.8-164.669.5000110.6P214 L219 L254P214-H217 WeakPolarHBondContact O-CB 3.26Å; P214-H217 PolarHBondContact O-N 3.47Å; P214-H217 VanDerWaalsContact O-N 3.1Å; H217-L219 PolarHBondContact O-N 3.19Å; H217-L219 VanDerWaalsContact O-N 3.09Å; H217-L254 HydrophobicContact CB-CD1 4.23Å; H217-L254 HydrophobicContact CB-CG 4.24Å; H217-L254 PolarHBondContact ND1-N 3.08Å
218D93.8Very high92.7Very high104 Ų10455.6 Ų55.656%0.55629%0.292SS*.THydrogen-bonded Turntrans60.811.9-178.4-68-33.7000115.7I251 I252D218-I251 VanDerWaalsContact CA-CG2 3.48Å; D218-I251 HydrophobicContact CB-CG2 4.41Å; D218-I252 PolarHBondContact N-O 3.47Å
219L95.1Very high91.9Very high65 Ų6555.9 Ų55.934%0.3430%0.301SS..  trans-88.4141.6168.9-66.1-174.4000111.2N215 L216 H217 V224 I251 I252N215-L219 WeakPolarHBondContact O-CD1 3.42Å; L216-L219 HydrophobicContact CD2-CD1 4.4Å; L216-L219 PolarHBondContact O-N 3.48Å; H217-L219 PolarHBondContact O-N 3.19Å; H217-L219 VanDerWaalsContact O-N 3.09Å; L219-V224 HydrophobicContact CB-CG2 4.22Å; L219-V224 HydrophobicContact CD1-CG2 4.4Å; L219-I251 WeakPolarHBondContact O-CA 3.5Å; L219-I252 PolarHBondContact O-N 3.3Å
220A94.2Very high91.2Very high6 Ų658.4 Ų58.45%0.0531%0.314CS..BIsolated β-bridgetrans-72.9149.1168.400000110.4K222 D223 T250 I251A220-K222 HydrophobicContact CB-CG 4.06Å; A220-K222 PolarHBondContact O-N 3.09Å; A220-D223 WeakPolarHBondContact CB-OD2 3.41Å; A220-D223 WeakPolarHBondContact O-CB 3.35Å; A220-D223 PolarHBondContact O-N 3.09Å; A220-T250 WeakPolarHBondContact CA-O 3.29Å; A220-I251 HydrophobicContact CB-CD1 3.85Å
221I91Very high90.6Very high4 Ų460.4 Ų60.42%0.02133%0.325CS..G310 helixtrans-54.6-37.9178.5-77.1172.5000112.6D223 V224 L227 L237 P246 P248 T250 I252I221-D223 PolarHBondContact O-N 3.26Å; I221-V224 PolarHBondContact O-N 3.35Å; I221-L227 HydrophobicContact CG2-CB 4.11Å; I221-L237 HydrophobicContact CD1-CD1 4.45Å; I221-P246 HydrophobicContact CD1-CB 3.34Å; I221-P246 HydrophobicContact CD1-CG 4.2Å; I221-P248 PolarHBondContact N-O 3.31Å; I221-T250 HydrophobicContact CD1-CG2 4.15Å; I221-T250 PolarHBondContact N-O 3.41Å; I221-I252 HydrophobicContact CD1-CG1 4.48Å; I221-I252 HydrophobicContact CG1-CD1 3.77Å; I221-I252 HydrophobicContact CG1-CG1 3.63Å
222K89.9Confident90.3Very high83 Ų8360.6 Ų60.636%0.36133%0.326SS..G310 helixtrans-62.7-25.5176.971.3-173.6-176.7-172.90113.6A220 V224 N228 P248 D249A220-K222 HydrophobicContact CB-CG 4.06Å; A220-K222 PolarHBondContact O-N 3.09Å; K222-V224 VanDerWaalsContact C-N 3.32Å; K222-N228 VanDerWaalsContact O-CB 3.3Å; K222-N228 WeakPolarHBondContact O-CB 3.33Å; K222-N228 VanDerWaalsContact O-CG 3.24Å; K222-N228 PolarHBondContact O-ND2 3.26Å; K222-P248 HydrophobicContact CB-CB 4.08Å; K222-P248 WeakPolarHBondContact CB-O 3.33Å; K222-P248 HydrophobicContact CD-CB 4.5Å; K222-P248 WeakPolarHBondContact CG-O 3.47Å; K222-P248 PolarHBondContact N-O 3.34Å; K222-D249 WeakPolarHBondContact CE-OD1 3.23Å; K222-D249 IonicContact NZ-OD1 2.75Å; K222-D249 PolarHBondContact NZ-OD1 3.17Å
223D92.2Very high90.2Very high93 Ų9357.6 Ų57.650%0.49731%0.313SS..G310 helixtrans-88.1-7.2-177.7-58.2-39.8000111.8A220 I221 P225A220-D223 WeakPolarHBondContact CB-OD2 3.41Å; A220-D223 WeakPolarHBondContact O-CB 3.35Å; A220-D223 PolarHBondContact O-N 3.09Å; I221-D223 PolarHBondContact O-N 3.26Å; D223-P225 WeakPolarHBondContact O-CD 3.15Å
224V92Very high90.1Very high3 Ų355.9 Ų55.92%0.01830%0.304CS..SBendtrans-94.4106.9176.4-179.40000109.4L216 L219 I221 K222 I226 L227 N228 I252L216-V224 HydrophobicContact CD2-CG1 3.99Å; L216-V224 HydrophobicContact CD2-CG2 3.92Å; L219-V224 HydrophobicContact CB-CG2 4.22Å; L219-V224 HydrophobicContact CD1-CG2 4.4Å; I221-V224 PolarHBondContact O-N 3.35Å; K222-V224 VanDerWaalsContact C-N 3.32Å; V224-I226 HydrophobicContact CG1-CG2 3.85Å; V224-I226 PolarHBondContact O-N 2.93Å; V224-I226 VanDerWaalsContact O-N 3.09Å; V224-L227 HydrophobicContact CB-CB 4.19Å; V224-L227 HydrophobicContact CB-CD1 4.18Å; V224-L227 HydrophobicContact CB-CG 4.38Å; V224-L227 HydrophobicContact CG1-CB 4.17Å; V224-L227 HydrophobicContact CG1-CD1 3.94Å; V224-L227 HydrophobicContact CG1-CG 3.94Å; V224-L227 PolarHBondContact O-N 3.05Å; V224-N228 PolarHBondContact O-N 3.3Å; V224-I252 HydrophobicContact CG2-CD1 3.86Å
225P89.2Confident90Very high113 Ų11351.6 Ų51.673%0.73428%0.276SS*.THydrogen-bonded Turntrans-57.8-34.2-169.7-27.636000114.4D223 L227 G229D223-P225 WeakPolarHBondContact O-CD 3.15Å; P225-L227 VanDerWaalsContact C-N 3.34Å; P225-G229 PolarHBondContact O-N 3.37Å; P225-G229 VanDerWaalsContact O-N 3.13Å
226I89Confident89.9Confident38 Ų3846.8 Ų46.820%0.19525%0.248CC..THydrogen-bonded Turntrans-74.5-24-179.8-163148.3000113.3V224 I232 N269 A270 V273 I274V224-I226 HydrophobicContact CG1-CG2 3.85Å; V224-I226 PolarHBondContact O-N 2.93Å; V224-I226 VanDerWaalsContact O-N 3.09Å; I226-I232 HydrophobicContact CG1-CD1 4.09Å; I226-N269 VanDerWaalsContact CD1-C 3.45Å; I226-N269 HydrophobicContact CD1-CB 3.9Å; I226-A270 VanDerWaalsContact CD1-CA 3.47Å; I226-A270 HydrophobicContact CD1-CB 4.04Å; I226-A270 HydrophobicContact CG1-CB 4.07Å; I226-V273 HydrophobicContact CD1-CG2 4.38Å; I226-V273 HydrophobicContact CG2-CG1 4.38Å; I226-I274 HydrophobicContact CG2-CD1 4.19Å; I226-I274 HydrophobicContact CG2-CG1 4.28Å
227L88.7Confident89.9Confident11 Ų1146.2 Ų46.26%0.05825%0.245CC..THydrogen-bonded Turntrans-96.2-24177.4-66.1176.8000112.9I221 V224 P225 C234 I252 L258 L260 I274I221-L227 HydrophobicContact CG2-CB 4.11Å; V224-L227 HydrophobicContact CB-CB 4.19Å; V224-L227 HydrophobicContact CB-CD1 4.18Å; V224-L227 HydrophobicContact CB-CG 4.38Å; V224-L227 HydrophobicContact CG1-CB 4.17Å; V224-L227 HydrophobicContact CG1-CD1 3.94Å; V224-L227 HydrophobicContact CG1-CG 3.94Å; V224-L227 PolarHBondContact O-N 3.05Å; P225-L227 VanDerWaalsContact C-N 3.34Å; L227-C234 HydrophobicContact CD2-CB 4.45Å; L227-I252 HydrophobicContact CD1-CD1 3.67Å; L227-L258 HydrophobicContact CD1-CD1 3.91Å; L227-L258 HydrophobicContact CD2-CD1 4.38Å; L227-L260 HydrophobicContact CD2-CD1 4.23Å; L227-L260 HydrophobicContact CD2-CD2 3.75Å; L227-I274 HydrophobicContact CD1-CD1 4.24Å; L227-I274 HydrophobicContact CD2-CD1 3.7Å; L227-I274 HydrophobicContact CG-CD1 4Å
228N83.4Confident90Very high98 Ų9844.5 Ų44.552%0.52424%0.237SC..SBendtrans-89.6-2.6173.9-164.226.3000113.1K222 V224K222-N228 VanDerWaalsContact O-CB 3.3Å; K222-N228 WeakPolarHBondContact O-CB 3.33Å; K222-N228 VanDerWaalsContact O-CG 3.24Å; K222-N228 PolarHBondContact O-ND2 3.26Å; V224-N228 PolarHBondContact O-N 3.3Å
229G79.8Confident89.9Confident29 Ų2942.1 Ų42.130%0.29922%0.22SC..SBendtrans-77.5159.4177.800000113.5P225 K231P225-G229 PolarHBondContact O-N 3.37Å; P225-G229 VanDerWaalsContact O-N 3.13Å; G229-K231 PolarHBondContact O-N 3.37Å
230D78.7Confident89.5Confident54 Ų5447.2 Ų47.229%0.28924%0.242SC..THydrogen-bonded Turntrans-76.6-1.8-179.5-79.9-52.6000114.7R307 S332 G333D230-R307 IonicContact OD1-NH2 3.52Å; D230-R307 PolarHBondContact OD1-NH2 3.34Å; D230-R307 IonicContact OD2-CZ 2.84Å; D230-R307 IonicContact OD2-NH2 3.66Å; D230-R307 PolarHBondContact OD2-NH2 2.95Å; D230-S332 WeakPolarHBondContact O-CB 3.44Å; D230-G333 PolarHBondContact OD1-N 3.36Å
231K84.3Confident89Confident131 Ų13154.3 Ų54.357%0.5727%0.274SS*.THydrogen-bonded Turntrans-94.2-21.3-173.9-58.4-169.2-175.81790114.3G229 D266G229-K231 PolarHBondContact O-N 3.37Å; K231-D266 HydrophobicContact CB-CB 4.24Å; K231-D266 WeakPolarHBondContact CD-OD1 3.28Å; K231-D266 IonicContact NZ-OD1 2.84Å
232I90.9Very high88.9Confident5 Ų558.6 Ų58.63%0.02630%0.301CS..EExtended strand (participates in β ladder)trans-133.8130.8-175.3-56.7177.5000108.7I226 L260 V261 D266 L267 A270I226-I232 HydrophobicContact CG1-CD1 4.09Å; I232-L260 HydrophobicContact CG2-CB 3.84Å; I232-L260 HydrophobicContact CG2-CD1 4.11Å; I232-L260 HydrophobicContact CG2-CD2 4.24Å; I232-L260 HydrophobicContact CG2-CG 4.29Å; I232-V261 WeakPolarHBondContact CA-O 3.37Å; I232-D266 HydrophobicContact CD1-CB 3.94Å; I232-D266 WeakPolarHBondContact CD1-O 3.49Å; I232-D266 HydrophobicContact CG1-CB 3.82Å; I232-L267 HydrophobicContact CG2-CD2 4.14Å; I232-A270 HydrophobicContact CD1-CB 3.62Å
233I91.6Very high89Confident24 Ų2455.3 Ų55.312%0.12329%0.287CS..EExtended strand (participates in β ladder)trans-105.6116.4173-57.3-60.6000108.7S235 V261 V318 V330I233-S235 PolarHBondContact O-N 3.28Å; I233-S235 VanDerWaalsContact O-N 3.15Å; I233-V261 HydrophobicContact CB-CB 4.47Å; I233-V261 PolarHBondContact N-O 3.2Å; I233-V261 PolarHBondContact O-N 3.2Å; I233-V318 HydrophobicContact CG2-CG2 3.59Å; I233-V330 HydrophobicContact CD1-CG1 4.39Å; I233-V330 HydrophobicContact CG1-CG1 3.68Å
234C93.2Very high88.9Confident4 Ų454.4 Ų54.43%0.02728%0.278CS..EExtended strand (participates in β ladder)trans-7796.5166.1-171.10000108.9L227 P246 L260L227-C234 HydrophobicContact CD2-CB 4.45Å; C234-P246 HydrophobicContact CB-CG 4.3Å; C234-P246 WeakPolarHBondContact O-CG 3.24Å; C234-L260 HydrophobicContact CB-CD2 3.72Å
235S91.6Very high88.9Confident0 Ų055 Ų550%028%0.282CS..EExtended strand (participates in β ladder)trans-77.1-34.2-173.368.60000113.1I233 H259 V318I233-S235 PolarHBondContact O-N 3.28Å; I233-S235 VanDerWaalsContact O-N 3.15Å; S235-H259 PolarHBondContact N-O 3.36Å; S235-H259 PolarHBondContact OG-CD2 3.35Å; S235-H259 PolarHBondContact OG-O 3.46Å; S235-V318 WeakPolarHBondContact O-CG1 3.29Å
236R92.8Very high88.9Confident29 Ų2949.6 Ų49.611%0.10925%0.247CC..EExtended strand (participates in β ladder)trans-149148.9-173-68.2163.6-79.1-173.1-7.3109.7L243 K244 H259 L282 L289 V346R236-L243 HydrophobicContact CB-CD1 4.11Å; R236-K244 WeakPolarHBondContact CA-O 3.25Å; R236-H259 HydrophobicContact CB-CB 3.98Å; R236-H259 PolarHBondContact NH2-CD2 3.48Å; R236-H259 PolarHBondContact NH2-CE1 3.02Å; R236-H259 VanDerWaalsContact NH2-CE1 3.29Å; R236-H259 PolarHBondContact NH2-NE2 2.91Å; R236-H259 PolarHBondContact O-N 2.79Å; R236-L282 PolarHBondContact NH1-O 3.45Å; R236-L289 HydrophobicContact CG-CD1 4.46Å; R236-V346 HydrophobicContact CG-CG1 3.91Å
237L94.1Very high88.9Confident0 Ų049.5 Ų49.50%025%0.25CC..EExtended strand (participates in β ladder)trans-126.9128.5170.4-178.3156.7000107.8I221 R239 K244 P246 T250 D256 L257 L258I221-L237 HydrophobicContact CD1-CD1 4.45Å; L237-R239 HydrophobicContact CD2-CB 3.97Å; L237-K244 HydrophobicContact CB-CG 4.49Å; L237-K244 HydrophobicContact CD2-CG 4.36Å; L237-K244 PolarHBondContact N-O 3.15Å; L237-K244 PolarHBondContact O-N 3.04Å; L237-P246 HydrophobicContact CB-CB 4.19Å; L237-P246 HydrophobicContact CB-CG 4.27Å; L237-T250 HydrophobicContact CD1-CG2 4.03Å; L237-D256 HydrophobicContact CG-CB 4.49Å; L237-L257 CarbonylContact C-O 3.22Å; L237-L257 VanDerWaalsContact CA-O 3.31Å; L237-L257 WeakPolarHBondContact CA-O 3.34Å; L237-L258 HydrophobicContact CB-CD2 4.02Å; L237-L258 HydrophobicContact CD1-CD2 3.5Å; L237-L258 HydrophobicContact CG-CD2 3.66Å
238K94.1Very high88.8Confident41 Ų4150.1 Ų50.118%0.17825%0.254CS..EExtended strand (participates in β ladder)trans-107.3120.1170.1-177.6171.7175.1169.30108.7E240 E241 T242 L243 L257 L282K238-E240 WeakPolarHBondContact CE-O 3.22Å; K238-E240 WeakPolarHBondContact CG-O 3.4Å; K238-E241 IonicContact NZ-OE1 3.73Å; K238-E241 IonicContact NZ-OE2 3.55Å; K238-E241 PolarHBondContact NZ-OE2 2.9Å; K238-T242 WeakPolarHBondContact CA-O 3.35Å; K238-L243 HydrophobicContact CB-CD1 3.76Å; K238-L243 HydrophobicContact CG-CD1 4.48Å; K238-L257 HydrophobicContact CB-CB 4.21Å; K238-L257 PolarHBondContact N-O 2.92Å; K238-L257 PolarHBondContact O-N 3.12Å; K238-L282 HydrophobicContact CB-CD2 4Å; K238-L282 HydrophobicContact CB-CG 3.98Å
239R92.5Very high89.1Confident54 Ų5450 Ų5020%0.20425%0.254CS..EExtended strand (participates in β ladder)trans-116.7119.6171.4-179171.3-61.5170.22.7107.6L237 E241 T242 I251 Q253 D256L237-R239 HydrophobicContact CD2-CB 3.97Å; R239-E241 PolarHBondContact O-N 3.23Å; R239-E241 VanDerWaalsContact O-N 3.16Å; R239-T242 PolarHBondContact N-O 2.94Å; R239-T242 PolarHBondContact O-N 3.36Å; R239-I251 PolarHBondContact NH2-O 3.03Å; R239-Q253 VanDerWaalsContact NE-OE1 3.17Å; R239-D256 WeakPolarHBondContact CB-OD1 3.31Å; R239-D256 WeakPolarHBondContact CG-OD1 3.43Å; R239-D256 IonicContact CZ-OD1 2.7Å; R239-D256 IonicContact CZ-OD2 2.76Å; R239-D256 IonicContact NE-OD1 3.46Å; R239-D256 PolarHBondContact NE-OD1 3.4Å; R239-D256 IonicContact NE-OD2 2.69Å; R239-D256 IonicContact NH2-OD1 3.86Å; R239-D256 PolarHBondContact NH2-OD1 3.44Å; R239-D256 IonicContact NH2-OD2 3.53Å; R239-D256 PolarHBondContact NH2-OD2 3.37Å
240E86.4Confident89.7Confident171 Ų17149.3 Ų49.380%0.79924%0.244SC*.THydrogen-bonded Turntrans51.5-120.2-171.2-56.8174.6176.800109.4K238K238-E240 WeakPolarHBondContact CE-O 3.22Å; K238-E240 WeakPolarHBondContact CG-O 3.4Å
241E84.8Confident90.5Very high156 Ų15650.2 Ų50.273%0.72925%0.248SC*.THydrogen-bonded Turntrans-95.4-2.2176.4-65.5-52.2146.200115K238 R239K238-E241 IonicContact NZ-OE1 3.73Å; K238-E241 IonicContact NZ-OE2 3.55Å; K238-E241 PolarHBondContact NZ-OE2 2.9Å; R239-E241 PolarHBondContact O-N 3.23Å; R239-E241 VanDerWaalsContact O-N 3.16Å
242T88.8Confident91Very high94 Ų9444 Ų4458%0.57722%0.221SC*.EExtended strand (participates in β ladder)trans-92.7120.7-177.8-54.30000110.9K238 R239K238-T242 WeakPolarHBondContact CA-O 3.35Å; R239-T242 PolarHBondContact N-O 2.94Å; R239-T242 PolarHBondContact O-N 3.36Å
243L90.8Very high91.2Very high13 Ų1347.3 Ų47.37%0.06824%0.236CC..EExtended strand (participates in β ladder)trans-96.3129.4171.3-168.172.3000109.3R236 K238 L282 T284 T287 L289R236-L243 HydrophobicContact CB-CD1 4.11Å; K238-L243 HydrophobicContact CB-CD1 3.76Å; K238-L243 HydrophobicContact CG-CD1 4.48Å; L243-L282 HydrophobicContact CD1-CB 4.24Å; L243-L282 HydrophobicContact CD1-CD2 4.32Å; L243-L282 HydrophobicContact CD1-CG 4.2Å; L243-T284 HydrophobicContact CD2-CG2 4.42Å; L243-T287 HydrophobicContact CB-CG2 4.23Å; L243-T287 HydrophobicContact CD2-CG2 3.94Å; L243-L289 HydrophobicContact CB-CD1 4.44Å; L243-L289 HydrophobicContact CD2-CD1 3.89Å; L243-L289 HydrophobicContact CG-CD1 3.82Å
244K91.5Very high91.4Very high74 Ų7450.2 Ų50.232%0.32225%0.251SS..EExtended strand (participates in β ladder)trans-138.816017762.5178.3177.4177.80112.3R236 L237 P246R236-K244 WeakPolarHBondContact CA-O 3.25Å; L237-K244 HydrophobicContact CB-CG 4.49Å; L237-K244 HydrophobicContact CD2-CG 4.36Å; L237-K244 PolarHBondContact N-O 3.15Å; L237-K244 PolarHBondContact O-N 3.04Å; K244-P246 WeakPolarHBondContact O-CD 3.35Å
245V91.3Very high91.4Very high16 Ų1652.1 Ų52.110%0.09727%0.272CS..PPolyproline II helixtrans-79.5119.8164.11780000107.3L289 V318V245-L289 HydrophobicContact CG2-CD1 4.3Å; V245-L289 HydrophobicContact CG2-CD2 4.16Å; V245-V318 HydrophobicContact CG1-CB 4.01Å; V245-V318 HydrophobicContact CG1-CG1 4.08Å
246P89.7Confident91.6Very high0 Ų052.2 Ų52.20%027%0.272CS..PPolyproline II helixtrans-71.9132.4-178.823-27.1000110.6I221 C234 L237 K244 T250 K312I221-P246 HydrophobicContact CD1-CB 3.34Å; I221-P246 HydrophobicContact CD1-CG 4.2Å; C234-P246 HydrophobicContact CB-CG 4.3Å; C234-P246 WeakPolarHBondContact O-CG 3.24Å; L237-P246 HydrophobicContact CB-CB 4.19Å; L237-P246 HydrophobicContact CB-CG 4.27Å; K244-P246 WeakPolarHBondContact O-CD 3.35Å; P246-T250 HydrophobicContact CB-CG2 4.4Å; P246-K312 WeakPolarHBondContact O-CE 3.48Å; P246-K312 PolarHBondContact O-NZ 2.74Å
247S87.8Confident91.8Very high35 Ų3551.7 Ų51.725%0.24527%0.271CS..PPolyproline II helixtrans-82.9163.6168.968.70000111.4D249 T250S247-D249 PolarHBondContact O-N 3.31Å; S247-T250 PolarHBondContact N-OG1 2.88Å; S247-T250 VanDerWaalsContact O-CB 3.27Å; S247-T250 WeakPolarHBondContact O-CB 3.42Å; S247-T250 PolarHBondContact O-N 3.43Å; S247-T250 PolarHBondContact O-OG1 3.28Å; S247-T250 PolarHBondContact OG-N 3.31Å; S247-T250 PolarHBondContact OG-OG1 3.42Å
248P86.3Confident91.8Very high24 Ų2451.7 Ų51.716%0.15627%0.271CS..THydrogen-bonded Turntrans-54.9-34.5173.3-25.435.1000113.5I221 K222 T250 E313I221-P248 PolarHBondContact N-O 3.31Å; K222-P248 HydrophobicContact CB-CB 4.08Å; K222-P248 WeakPolarHBondContact CB-O 3.33Å; K222-P248 HydrophobicContact CD-CB 4.5Å; K222-P248 WeakPolarHBondContact CG-O 3.47Å; K222-P248 PolarHBondContact N-O 3.34Å; P248-T250 VanDerWaalsContact C-N 3.33Å; P248-E313 HydrophobicContact CG-CG 4.15Å; P248-E313 WeakPolarHBondContact CG-OE1 3.4Å
249D90.2Very high91.9Very high97 Ų9750.5 Ų50.552%0.51927%0.267SS..THydrogen-bonded Turntrans-87.92.5179-57.1-51.3000113.6K222 S247 I251K222-D249 WeakPolarHBondContact CE-OD1 3.23Å; K222-D249 IonicContact NZ-OD1 2.75Å; K222-D249 PolarHBondContact NZ-OD1 3.17Å; S247-D249 PolarHBondContact O-N 3.31Å; D249-I251 PolarHBondContact O-N 3.13Å; D249-I251 VanDerWaalsContact O-N 3.12Å
250T92Very high92Very high13 Ų1348 Ų488%0.0826%0.257CS..PPolyproline II helixtrans-64.9118177.6-68.80000109.5A220 I221 L237 P246 S247 P248A220-T250 WeakPolarHBondContact CA-O 3.29Å; I221-T250 HydrophobicContact CD1-CG2 4.15Å; I221-T250 PolarHBondContact N-O 3.41Å; L237-T250 HydrophobicContact CD1-CG2 4.03Å; P246-T250 HydrophobicContact CB-CG2 4.4Å; S247-T250 PolarHBondContact N-OG1 2.88Å; S247-T250 VanDerWaalsContact O-CB 3.27Å; S247-T250 WeakPolarHBondContact O-CB 3.42Å; S247-T250 PolarHBondContact O-N 3.43Å; S247-T250 PolarHBondContact O-OG1 3.28Å; S247-T250 PolarHBondContact OG-N 3.31Å; S247-T250 PolarHBondContact OG-OG1 3.42Å; P248-T250 VanDerWaalsContact C-N 3.33Å
251I95.4Very high92.2Very high73 Ų7339.9 Ų39.937%0.37422%0.22SC..BIsolated β-bridgetrans-75.2124.1176.5-54.9-56.3000109.9D218 L219 A220 R239 D249D218-I251 VanDerWaalsContact CA-CG2 3.48Å; D218-I251 HydrophobicContact CB-CG2 4.41Å; L219-I251 WeakPolarHBondContact O-CA 3.5Å; A220-I251 HydrophobicContact CB-CD1 3.85Å; R239-I251 PolarHBondContact NH2-O 3.03Å; D249-I251 PolarHBondContact O-N 3.13Å; D249-I251 VanDerWaalsContact O-N 3.12Å
252I95.1Very high92.5Very high0 Ų032.5 Ų32.50%019%0.185CC..PPolyproline II helixtrans-78136.2179.2-58.5177.3000109.5V211 D218 L219 I221 V224 L227V211-I252 HydrophobicContact CB-CG2 4.28Å; V211-I252 HydrophobicContact CG1-CG2 3.75Å; V211-I252 HydrophobicContact CG2-CG2 3.81Å; D218-I252 PolarHBondContact N-O 3.47Å; L219-I252 PolarHBondContact O-N 3.3Å; I221-I252 HydrophobicContact CD1-CG1 4.48Å; I221-I252 HydrophobicContact CG1-CD1 3.77Å; I221-I252 HydrophobicContact CG1-CG1 3.63Å; V224-I252 HydrophobicContact CG2-CD1 3.86Å; L227-I252 HydrophobicContact CD1-CD1 3.67Å
253Q95.7Very high92.2Very high76 Ų7631.9 Ų31.936%0.35518%0.175SC..  trans-117155.3173.6-71.3178.5-1000110.9R239 G255 D256R239-Q253 VanDerWaalsContact NE-OE1 3.17Å; Q253-G255 PolarHBondContact O-N 2.66Å; Q253-D256 PolarHBondContact N-OD2 3.23Å; Q253-D256 WeakPolarHBondContact O-CB 3.16Å; Q253-D256 PolarHBondContact O-N 2.92Å
254L95Very high91.9Very high84 Ų8432.9 Ų32.944%0.4418%0.183SC..THydrogen-bonded Turntrans-64.3134.8174.1-82.3162.2000108.9H217 D256H217-L254 HydrophobicContact CB-CD1 4.23Å; H217-L254 HydrophobicContact CB-CG 4.24Å; H217-L254 PolarHBondContact ND1-N 3.08Å; L254-D256 VanDerWaalsContact C-N 3.34Å
255G93.9Very high91.6Very high44 Ų4432.4 Ų32.445%0.45419%0.193SC..THydrogen-bonded Turntrans87-7.4-176.200000115.2V211 Q253V211-G255 PolarHBondContact O-N 3.36Å; Q253-G255 PolarHBondContact O-N 2.66Å
256D96Very high91.6Very high3 Ų333 Ų332%0.01620%0.195CC..  trans-56.2144171.1-81.4-18.2000110.7R210 V211 L237 R239 Q253 L254R210-D256 CarbonylContact C-O 3.35Å; R210-D256 WeakPolarHBondContact CA-O 3.49Å; V211-D256 HydrophobicContact CB-CB 4.39Å; V211-D256 HydrophobicContact CG2-CB 3.95Å; V211-D256 WeakPolarHBondContact CG2-O 3.36Å; V211-D256 PolarHBondContact N-O 3.48Å; L237-D256 HydrophobicContact CG-CB 4.49Å; R239-D256 WeakPolarHBondContact CB-OD1 3.31Å; R239-D256 WeakPolarHBondContact CG-OD1 3.43Å; R239-D256 IonicContact CZ-OD1 2.7Å; R239-D256 IonicContact CZ-OD2 2.76Å; R239-D256 IonicContact NE-OD1 3.46Å; R239-D256 PolarHBondContact NE-OD1 3.4Å; R239-D256 IonicContact NE-OD2 2.69Å; R239-D256 IonicContact NH2-OD1 3.86Å; R239-D256 PolarHBondContact NH2-OD1 3.44Å; R239-D256 IonicContact NH2-OD2 3.53Å; R239-D256 PolarHBondContact NH2-OD2 3.37Å; Q253-D256 PolarHBondContact N-OD2 3.23Å; Q253-D256 WeakPolarHBondContact O-CB 3.16Å; Q253-D256 PolarHBondContact O-N 2.92Å; L254-D256 VanDerWaalsContact C-N 3.34Å
257L95.7Very high91.7Very high17 Ų1733.1 Ų33.19%0.08920%0.196CC..EExtended strand (participates in β ladder)trans-105.2124.3171.9-54.6178.9000109.7I209 R210 L237 K238 V278 T280 L282I209-L257 CarbonylContact O-C 3.16Å; I209-L257 WeakPolarHBondContact O-CA 3.43Å; R210-L257 HydrophobicContact CB-CD2 3.6Å; R210-L257 HydrophobicContact CG-CD2 3.84Å; L237-L257 CarbonylContact C-O 3.22Å; L237-L257 VanDerWaalsContact CA-O 3.31Å; L237-L257 WeakPolarHBondContact CA-O 3.34Å; K238-L257 HydrophobicContact CB-CB 4.21Å; K238-L257 PolarHBondContact N-O 2.92Å; K238-L257 PolarHBondContact O-N 3.12Å; L257-V278 HydrophobicContact CD2-CG2 3.93Å; L257-T280 HydrophobicContact CD1-CG2 3.76Å; L257-L282 HydrophobicContact CB-CD1 3.95Å; L257-L282 HydrophobicContact CB-CD2 4.07Å; L257-L282 HydrophobicContact CB-CG 4.49Å; L257-L282 HydrophobicContact CD1-CD1 4.03Å; L257-L282 WeakPolarHBondContact O-CD2 3.41Å
258L95.6Very high91.8Very high0 Ų036.1 Ų36.10%021%0.206CC..EExtended strand (participates in β ladder)trans-108.3128.2179.6-55.2-176.8000110.4N208 I209 V211 L227 L237 L260 I274N208-L258 CarbonylContact C-O 3.59Å; N208-L258 VanDerWaalsContact CA-O 3.29Å; N208-L258 WeakPolarHBondContact CA-O 3.09Å; I209-L258 PolarHBondContact N-O 3.09Å; I209-L258 PolarHBondContact O-N 3.34Å; V211-L258 HydrophobicContact CG2-CD1 3.89Å; V211-L258 HydrophobicContact CG2-CG 3.96Å; L227-L258 HydrophobicContact CD1-CD1 3.91Å; L227-L258 HydrophobicContact CD2-CD1 4.38Å; L237-L258 HydrophobicContact CB-CD2 4.02Å; L237-L258 HydrophobicContact CD1-CD2 3.5Å; L237-L258 HydrophobicContact CG-CD2 3.66Å; L258-L260 HydrophobicContact CB-CD2 3.95Å; L258-L260 HydrophobicContact CB-CG 4.36Å; L258-I274 HydrophobicContact CD1-CD1 4.5Å; L258-I274 HydrophobicContact CD1-CG2 4.22Å
259H95Very high92.1Very high17 Ų1738.6 Ų38.68%0.07922%0.218CC..EExtended strand (participates in β ladder)trans-94105.7170.2-169.489.4000110.2T206 N208 S235 R236 L282T206-H259 WeakPolarHBondContact CB-NE2 3.38Å; N208-H259 PolarHBondContact OD1-ND1 3.08Å; S235-H259 PolarHBondContact N-O 3.36Å; S235-H259 PolarHBondContact OG-CD2 3.35Å; S235-H259 PolarHBondContact OG-O 3.46Å; R236-H259 HydrophobicContact CB-CB 3.98Å; R236-H259 PolarHBondContact NH2-CD2 3.48Å; R236-H259 PolarHBondContact NH2-CE1 3.02Å; R236-H259 VanDerWaalsContact NH2-CE1 3.29Å; R236-H259 PolarHBondContact NH2-NE2 2.91Å; R236-H259 PolarHBondContact O-N 2.79Å; H259-L282 HydrophobicContact CB-CB 4.33Å; H259-L282 HydrophobicContact CB-CD2 3.87Å
260L94.7Very high92.3Very high0 Ų034 Ų340%019%0.193CC..EExtended strand (participates in β ladder)trans-100.4142-176.4-55.5-169000111.2T206 I207 I209 L227 I232 C234 L258 L267 A270 I274T206-L260 WeakPolarHBondContact CA-O 3.24Å; I207-L260 HydrophobicContact CG1-CB 4.23Å; I207-L260 PolarHBondContact N-O 3.21Å; I207-L260 VanDerWaalsContact N-O 3.1Å; I207-L260 PolarHBondContact O-N 2.97Å; I209-L260 HydrophobicContact CD1-CD1 3.74Å; L227-L260 HydrophobicContact CD2-CD1 4.23Å; L227-L260 HydrophobicContact CD2-CD2 3.75Å; I232-L260 HydrophobicContact CG2-CB 3.84Å; I232-L260 HydrophobicContact CG2-CD1 4.11Å; I232-L260 HydrophobicContact CG2-CD2 4.24Å; I232-L260 HydrophobicContact CG2-CG 4.29Å; C234-L260 HydrophobicContact CB-CD2 3.72Å; L258-L260 HydrophobicContact CB-CD2 3.95Å; L258-L260 HydrophobicContact CB-CG 4.36Å; L260-L267 HydrophobicContact CB-CD2 3.7Å; L260-A270 HydrophobicContact CD1-CB 3.74Å; L260-I274 HydrophobicContact CD1-CD1 4.06Å
261V91.4Very high92.4Very high2 Ų236 Ų361%0.01220%0.202CC..EExtended strand (participates in β ladder)trans-124.4124.7177.5-171.60000108.2I204 K205 T206 I232 I233 R321I204-V261 HydrophobicContact CG2-CG1 3.35Å; K205-V261 WeakPolarHBondContact O-CA 3.39Å; T206-V261 HydrophobicContact CG2-CB 4.27Å; T206-V261 HydrophobicContact CG2-CG1 4.07Å; T206-V261 HydrophobicContact CG2-CG2 3.83Å; I232-V261 WeakPolarHBondContact CA-O 3.37Å; I233-V261 HydrophobicContact CB-CB 4.47Å; I233-V261 PolarHBondContact N-O 3.2Å; I233-V261 PolarHBondContact O-N 3.2Å; V261-R321 HydrophobicContact CG1-CG 3.83Å
262G90.3Very high92.3Very high0 Ų038.4 Ų38.40%022%0.215CC..EExtended strand (participates in β ladder)trans-177.6-177.2-173.300000113K205K205-G262 PolarHBondContact N-O 3.26Å; K205-G262 PolarHBondContact O-N 3.39Å; K205-G262 VanDerWaalsContact O-N 3.1Å
263Q83.8Confident92.2Very high81 Ų8141.5 Ų41.538%0.37923%0.234SC..  trans-75.6148.9168.4-64.1-156.113.600110.4A202 A265 D266 L267A202-Q263 HydrophobicContact CB-CB 4.32Å; Q263-A265 VanDerWaalsContact C-N 3.28Å; Q263-A265 PolarHBondContact O-N 3.37Å; Q263-D266 PolarHBondContact O-N 2.98Å; Q263-L267 WeakPolarHBondContact O-CG 3.07Å; Q263-L267 PolarHBondContact O-N 2.85Å
264P83.7Confident92.2Very high35 Ų3538 Ų3823%0.22722%0.217CC..Hα-helixtrans-53.6-39.3-176.5-26.136.2000114.2A202 K205 L267 H268A202-P264 HydrophobicContact CB-CG 3.71Å; K205-P264 HydrophobicContact CD-CG 4.1Å; K205-P264 HydrophobicContact CG-CG 4.23Å; P264-L267 PolarHBondContact O-N 3.31Å; P264-H268 WeakPolarHBondContact O-CB 3.34Å; P264-H268 PolarHBondContact O-N 3.49Å
265A86Confident92.2Very high64 Ų6434.9 Ų34.953%0.52921%0.205SC..Hα-helixtrans-65.2-42.8178.100000112Q263 H268 N269Q263-A265 VanDerWaalsContact C-N 3.28Å; Q263-A265 PolarHBondContact O-N 3.37Å; A265-H268 PolarHBondContact O-N 3.45Å; A265-N269 VanDerWaalsContact O-CG 3.3Å; A265-N269 PolarHBondContact O-N 3.19Å; A265-N269 VanDerWaalsContact O-N 3.08Å; A265-N269 PolarHBondContact O-ND2 3.34Å
266D89.2Confident92.1Very high27 Ų2738 Ų3814%0.14421%0.208CC..Hα-helixtrans-69.6-40.9177.8-60.3-54.6000111K231 I232 Q263 H268 N269 A270K231-D266 HydrophobicContact CB-CB 4.24Å; K231-D266 WeakPolarHBondContact CD-OD1 3.28Å; K231-D266 IonicContact NZ-OD1 2.84Å; I232-D266 HydrophobicContact CD1-CB 3.94Å; I232-D266 WeakPolarHBondContact CD1-O 3.49Å; I232-D266 HydrophobicContact CG1-CB 3.82Å; Q263-D266 PolarHBondContact O-N 2.98Å; D266-H268 VanDerWaalsContact C-N 3.33Å; D266-H268 PolarHBondContact O-N 3Å; D266-N269 WeakPolarHBondContact O-CB 3.27Å; D266-N269 PolarHBondContact O-N 3.03Å; D266-A270 PolarHBondContact O-N 3.4Å
267L91.9Very high92Very high4 Ų441.9 Ų41.92%0.02123%0.226CC..Hα-helixtrans-61.8-39.7174.8-69.1-178.7000112.3K205 I207 I232 L260 Q263 P264 A270 Q271K205-L267 HydrophobicContact CB-CD1 3.81Å; I207-L267 HydrophobicContact CD1-CB 3.77Å; I207-L267 HydrophobicContact CD1-CD2 4.28Å; I207-L267 HydrophobicContact CD1-CG 4.45Å; I207-L267 HydrophobicContact CG1-CB 4.23Å; I207-L267 HydrophobicContact CG1-CD1 4.29Å; I207-L267 HydrophobicContact CG1-CD2 4.03Å; I207-L267 HydrophobicContact CG1-CG 4.4Å; I207-L267 HydrophobicContact CG2-CD1 4.27Å; I232-L267 HydrophobicContact CG2-CD2 4.14Å; L260-L267 HydrophobicContact CB-CD2 3.7Å; Q263-L267 WeakPolarHBondContact O-CG 3.07Å; Q263-L267 PolarHBondContact O-N 2.85Å; P264-L267 PolarHBondContact O-N 3.31Å; L267-A270 WeakPolarHBondContact O-CB 3.5Å; L267-A270 PolarHBondContact O-N 3.29Å; L267-Q271 PolarHBondContact O-N 2.95Å
268H91.9Very high91.8Very high97 Ų9741.8 Ų41.845%0.44923%0.226SC..Hα-helixtrans-64.5-42.7174.8-176.459.5000111.7P264 A265 D266 A270 Q271 L272P264-H268 WeakPolarHBondContact O-CB 3.34Å; P264-H268 PolarHBondContact O-N 3.49Å; A265-H268 PolarHBondContact O-N 3.45Å; D266-H268 VanDerWaalsContact C-N 3.33Å; D266-H268 PolarHBondContact O-N 3Å; H268-A270 VanDerWaalsContact C-N 3.26Å; H268-A270 PolarHBondContact O-N 3.19Å; H268-Q271 WeakPolarHBondContact O-CB 3.44Å; H268-Q271 PolarHBondContact O-N 3.35Å; H268-L272 WeakPolarHBondContact O-CG 3.25Å; H268-L272 PolarHBondContact O-N 3.35Å
269N92.1Very high91.3Very high77 Ų7749.8 Ų49.841%0.41227%0.269SS..Hα-helixtrans-60.6-38.4173.3-67.5-26.6000111.7I226 A265 D266 L272 V273I226-N269 VanDerWaalsContact CD1-C 3.45Å; I226-N269 HydrophobicContact CD1-CB 3.9Å; A265-N269 VanDerWaalsContact O-CG 3.3Å; A265-N269 PolarHBondContact O-N 3.19Å; A265-N269 VanDerWaalsContact O-N 3.08Å; A265-N269 PolarHBondContact O-ND2 3.34Å; D266-N269 WeakPolarHBondContact O-CB 3.27Å; D266-N269 PolarHBondContact O-N 3.03Å; N269-L272 PolarHBondContact O-N 2.94Å; N269-V273 WeakPolarHBondContact O-CG2 3.44Å; N269-V273 PolarHBondContact O-N 3.35Å
270A93.5Very high90.6Very high0 Ų051.8 Ų51.80%028%0.283CS..Hα-helixtrans-65.3-41.5176.200000111.9I209 I226 I232 L260 D266 L267 H268 V273 I274I209-A270 HydrophobicContact CD1-CB 4.3Å; I226-A270 VanDerWaalsContact CD1-CA 3.47Å; I226-A270 HydrophobicContact CD1-CB 4.04Å; I226-A270 HydrophobicContact CG1-CB 4.07Å; I232-A270 HydrophobicContact CD1-CB 3.62Å; L260-A270 HydrophobicContact CD1-CB 3.74Å; D266-A270 PolarHBondContact O-N 3.4Å; L267-A270 WeakPolarHBondContact O-CB 3.5Å; L267-A270 PolarHBondContact O-N 3.29Å; H268-A270 VanDerWaalsContact C-N 3.26Å; H268-A270 PolarHBondContact O-N 3.19Å; A270-V273 PolarHBondContact O-N 3.37Å; A270-I274 HydrophobicContact CB-CD1 4.03Å; A270-I274 VanDerWaalsContact O-CB 3.23Å; A270-I274 WeakPolarHBondContact O-CB 3.36Å; A270-I274 WeakPolarHBondContact O-CG1 3.46Å; A270-I274 PolarHBondContact O-N 3Å
271Q94.7Very high89.8Confident56 Ų5655.9 Ų55.926%0.26231%0.311SS..Hα-helixtrans-57.2-50.3173.1-175.7-173.35.200111.1I209 L267 H268 V273 I274 G275I209-Q271 HydrophobicContact CD1-CB 3.99Å; L267-Q271 PolarHBondContact O-N 2.95Å; H268-Q271 WeakPolarHBondContact O-CB 3.44Å; H268-Q271 PolarHBondContact O-N 3.35Å; Q271-V273 PolarHBondContact O-N 3.41Å; Q271-V273 VanDerWaalsContact O-N 3.16Å; Q271-I274 PolarHBondContact O-N 2.86Å; Q271-G275 CarbonylContact C-O 3.23Å; Q271-G275 WeakPolarHBondContact CG-O 3.3Å; Q271-G275 PolarHBondContact O-N 3.4Å; Q271-G275 VanDerWaalsContact O-N 3.1Å
272L93.4Very high89.3Confident123 Ų12356 Ų5664%0.64431%0.312SS*.Hα-helixtrans-57.6-32.9-179.8-68.5173.2000113.5H268 N269H268-L272 WeakPolarHBondContact O-CG 3.25Å; H268-L272 PolarHBondContact O-N 3.35Å; N269-L272 PolarHBondContact O-N 2.94Å
273V93.5Very high88.6Confident65 Ų6558.3 Ų58.339%0.39433%0.328SS..Hα-helixtrans-91.2-37.7-177.3176.60000112.6N213 I226 N269 A270 Q271N213-V273 VanDerWaalsContact CB-O 3.31Å; N213-V273 WeakPolarHBondContact CB-O 3.32Å; N213-V273 PolarHBondContact ND2-O 3.45Å; I226-V273 HydrophobicContact CD1-CG2 4.38Å; I226-V273 HydrophobicContact CG2-CG1 4.38Å; N269-V273 WeakPolarHBondContact O-CG2 3.44Å; N269-V273 PolarHBondContact O-N 3.35Å; A270-V273 PolarHBondContact O-N 3.37Å; Q271-V273 PolarHBondContact O-N 3.41Å; Q271-V273 VanDerWaalsContact O-N 3.16Å
274I95.3Very high88.3Confident1 Ų155.6 Ų55.61%0.00532%0.317CS..Hα-helixtrans-92.1-42.1-168.2-60.3170.3000111.9I209 V211 E212 N213 L216 I226 L227 L258 L260 A270 Q271I209-I274 HydrophobicContact CG2-CB 3.95Å; I209-I274 HydrophobicContact CG2-CG2 3.63Å; V211-I274 HydrophobicContact CB-CG2 4.4Å; V211-I274 HydrophobicContact CG2-CG2 3.85Å; E212-I274 PolarHBondContact N-O 3.43Å; N213-I274 WeakPolarHBondContact CB-O 3.44Å; N213-I274 PolarHBondContact N-O 2.85Å; L216-I274 HydrophobicContact CD1-CB 4.11Å; L216-I274 HydrophobicContact CD1-CG1 3.91Å; L216-I274 HydrophobicContact CD1-CG2 4.11Å; I226-I274 HydrophobicContact CG2-CD1 4.19Å; I226-I274 HydrophobicContact CG2-CG1 4.28Å; L227-I274 HydrophobicContact CD1-CD1 4.24Å; L227-I274 HydrophobicContact CD2-CD1 3.7Å; L227-I274 HydrophobicContact CG-CD1 4Å; L258-I274 HydrophobicContact CD1-CD1 4.5Å; L258-I274 HydrophobicContact CD1-CG2 4.22Å; L260-I274 HydrophobicContact CD1-CD1 4.06Å; A270-I274 HydrophobicContact CB-CD1 4.03Å; A270-I274 VanDerWaalsContact O-CB 3.23Å; A270-I274 WeakPolarHBondContact O-CB 3.36Å; A270-I274 WeakPolarHBondContact O-CG1 3.46Å; A270-I274 PolarHBondContact O-N 3Å; Q271-I274 PolarHBondContact O-N 2.86Å
275G94.2Very high87.8Confident19 Ų1962.7 Ų62.720%0.19634%0.344CS..EExtended strand (participates in β ladder)trans150.2-154.9-176.300000113.7R210 Q271R210-G275 WeakPolarHBondContact O-CA 3.41Å; Q271-G275 CarbonylContact C-O 3.23Å; Q271-G275 WeakPolarHBondContact CG-O 3.3Å; Q271-G275 PolarHBondContact O-N 3.4Å; Q271-G275 VanDerWaalsContact O-N 3.1Å
276Q93.2Very high87.2Confident109 Ų10964 Ų6451%0.50936%0.363SS..EExtended strand (participates in β ladder)trans-85.5138.2-170.4-160.9-179.211.200112.9I209 R210I209-Q276 CarbonylContact C-O 3.19Å; I209-Q276 WeakPolarHBondContact CA-O 3.28Å; R210-Q276 PolarHBondContact N-O 2.88Å; R210-Q276 PolarHBondContact O-N 3.4Å
277E93.2Very high86.9Confident85 Ų8565.3 Ų65.340%0.39737%0.372SS..EExtended strand (participates in β ladder)trans-67.1136.5167-176.6173.7-171.800110I207 N208I207-E277 HydrophobicContact CB-CG 4.42Å; I207-E277 VanDerWaalsContact CG2-OE1 3.31Å; I207-E277 WeakPolarHBondContact CG2-OE1 3.41Å; N208-E277 CarbonylContact O-C 3.58Å; N208-E277 WeakPolarHBondContact O-CA 3.35Å
278V92.2Very high86.6Confident16 Ų1669.5 Ų69.510%0.09740%0.395CS..  trans-129.6145.9-178.3-63.30000111.7N208 R210 L257 T280N208-V278 HydrophobicContact CB-CG2 3.99Å; N208-V278 WeakPolarHBondContact CB-O 3.33Å; N208-V278 PolarHBondContact O-N 3Å; R210-V278 HydrophobicContact CB-CG1 3.93Å; L257-V278 HydrophobicContact CD2-CG2 3.93Å; V278-T280 PolarHBondContact O-N 2.87Å
279D84.7Confident86.5Confident167 Ų16765.2 Ų65.289%0.89338%0.376SS*.  trans-78.8-5176.6-66.3-40.8000113.4S281D279-S281 PolarHBondContact O-N 2.86Å; D279-S281 VanDerWaalsContact O-N 3.13Å
280T80.3Confident86.4Confident60 Ų6068.1 Ų68.137%0.36838%0.381SS..  trans-56.7120.1179.9-53.70000110.5N208 L257 V278 L282N208-T280 PolarHBondContact ND2-O 2.71Å; L257-T280 HydrophobicContact CD1-CG2 3.76Å; V278-T280 PolarHBondContact O-N 2.87Å; T280-L282 VanDerWaalsContact O-CD1 3.26Å; T280-L282 WeakPolarHBondContact O-CD1 3.5Å; T280-L282 PolarHBondContact O-N 3.46Å
281S76.8Confident86.2Confident86 Ų8671.5 Ų71.560%0.60140%0.401SS*.  trans-73.1119.5-177.4-174.10000111.8D279 S283D279-S281 PolarHBondContact O-N 2.86Å; D279-S281 VanDerWaalsContact O-N 3.13Å; S281-S283 PolarHBondContact O-N 3.38Å; S281-S283 WeakPolarHBondContact OG-CB 3.46Å; S281-S283 PolarHBondContact OG-N 3.44Å
282L80.6Confident85.9Confident5 Ų571.7 Ų71.73%0.02640%0.402CS..  trans-91.242.3168.9-82.470.2000110.9N208 R236 K238 L243 L257 H259 T280N208-L282 HydrophobicContact CB-CD1 4.13Å; R236-L282 PolarHBondContact NH1-O 3.45Å; K238-L282 HydrophobicContact CB-CD2 4Å; K238-L282 HydrophobicContact CB-CG 3.98Å; L243-L282 HydrophobicContact CD1-CB 4.24Å; L243-L282 HydrophobicContact CD1-CD2 4.32Å; L243-L282 HydrophobicContact CD1-CG 4.2Å; L257-L282 HydrophobicContact CB-CD1 3.95Å; L257-L282 HydrophobicContact CB-CD2 4.07Å; L257-L282 HydrophobicContact CB-CG 4.49Å; L257-L282 HydrophobicContact CD1-CD1 4.03Å; L257-L282 WeakPolarHBondContact O-CD2 3.41Å; H259-L282 HydrophobicContact CB-CB 4.33Å; H259-L282 HydrophobicContact CB-CD2 3.87Å; T280-L282 VanDerWaalsContact O-CD1 3.26Å; T280-L282 WeakPolarHBondContact O-CD1 3.5Å; T280-L282 PolarHBondContact O-N 3.46Å
283S77.4Confident85.7Confident47 Ų4772.5 Ų72.533%0.32940%0.396SS..  trans-63.4142.4179.8-172.50000111.3S281 K285S281-S283 PolarHBondContact O-N 3.38Å; S281-S283 WeakPolarHBondContact OG-CB 3.46Å; S281-S283 PolarHBondContact OG-N 3.44Å; S283-K285 WeakPolarHBondContact OG-CB 3.29Å; S283-K285 PolarHBondContact OG-N 2.86Å
284T75.6Confident85.5Confident25 Ų2569.4 Ų69.415%0.15338%0.378CS..  trans-78.6-10.9171.3590000112.3L243 G286 T287 L289 V291L243-T284 HydrophobicContact CD2-CG2 4.42Å; T284-G286 PolarHBondContact O-N 3.11Å; T284-T287 WeakPolarHBondContact CA-OG1 3.48Å; T284-T287 PolarHBondContact O-N 2.85Å; T284-T287 VanDerWaalsContact O-N 3.08Å; T284-T287 PolarHBondContact O-OG1 3.49Å; T284-L289 WeakPolarHBondContact CB-O 3.46Å; T284-L289 HydrophobicContact CG2-CB 3.97Å; T284-V291 HydrophobicContact CG2-CG2 3.89Å
285K74.9Confident85.1Confident184 Ų18470 Ų7080%0.838%0.381SS*.THydrogen-bonded Turntrans-63.9123.5178.6-70.4-173.5177.8-177.30110S283 T287S283-K285 WeakPolarHBondContact OG-CB 3.29Å; S283-K285 PolarHBondContact OG-N 2.86Å; K285-T287 VanDerWaalsContact C-N 3.34Å
286G71.8Confident84.7Confident90 Ų9069.1 Ų69.193%0.92837%0.372SS*.THydrogen-bonded Turntrans83.38-177.500000114.4T284T284-G286 PolarHBondContact O-N 3.11Å
287T83.7Confident84Confident55 Ų5564 Ų6434%0.33735%0.349SS..SBendtrans-111.6174.2173.9720000110.8L243 T284 K285 L289L243-T287 HydrophobicContact CB-CG2 4.23Å; L243-T287 HydrophobicContact CD2-CG2 3.94Å; T284-T287 WeakPolarHBondContact CA-OG1 3.48Å; T284-T287 PolarHBondContact O-N 2.85Å; T284-T287 VanDerWaalsContact O-N 3.08Å; T284-T287 PolarHBondContact O-OG1 3.49Å; K285-T287 VanDerWaalsContact C-N 3.34Å; T287-L289 PolarHBondContact O-N 2.8Å; T287-L289 PolarHBondContact OG1-N 3.48Å
288D85.5Confident83.3Confident93 Ų9362.1 Ų62.150%0.49734%0.341SS..SBendtrans-78.9-3.917268.8-36000113.4P349D288-P349 WeakPolarHBondContact O-CD 3.45Å
289L90.6Very high82.2Confident7 Ų764.8 Ų64.84%0.03735%0.352CS..  trans-90.4151.9174.3-60.3-177.3000111.7R236 L243 V245 T284 T287 G347 R348R236-L289 HydrophobicContact CG-CD1 4.46Å; L243-L289 HydrophobicContact CB-CD1 4.44Å; L243-L289 HydrophobicContact CD2-CD1 3.89Å; L243-L289 HydrophobicContact CG-CD1 3.82Å; V245-L289 HydrophobicContact CG2-CD1 4.3Å; V245-L289 HydrophobicContact CG2-CD2 4.16Å; T284-L289 WeakPolarHBondContact CB-O 3.46Å; T284-L289 HydrophobicContact CG2-CB 3.97Å; T287-L289 PolarHBondContact O-N 2.8Å; T287-L289 PolarHBondContact OG1-N 3.48Å; L289-G347 CarbonylContact C-O 3.59Å; L289-G347 WeakPolarHBondContact CA-O 3.5Å; L289-R348 HydrophobicContact CD2-CG 3.89Å
290R89.1Confident81.9Confident138 Ų13862.3 Ų62.352%0.52134%0.339SS..EExtended strand (participates in β ladder)trans-132.4161.4169.8-73.4-168.1-179.2177.51.2111.1V346 G347 P349 I352R290-V346 WeakPolarHBondContact O-CA 3.18Å; R290-G347 PolarHBondContact N-O 3.4Å; R290-G347 PolarHBondContact O-N 2.91Å; R290-P349 HydrophobicContact CG-CG 4.13Å; R290-I352 HydrophobicContact CB-CD1 4.08Å; R290-I352 WeakPolarHBondContact O-CD1 3.47Å
291V90.2Very high81.8Confident70 Ų7059.6 Ų59.642%0.42432%0.323SS..EExtended strand (participates in β ladder)trans-114.9119167.7-175.50000107T284 L345 V346T284-V291 HydrophobicContact CG2-CG2 3.89Å; V291-L345 CarbonylContact C-O 3.55Å; V291-L345 VanDerWaalsContact CA-O 3.28Å; V291-L345 WeakPolarHBondContact CA-O 3.31Å; V291-V346 HydrophobicContact CG1-CG2 4.26Å; V291-V346 HydrophobicContact CG2-CG1 4.32Å; V291-V346 HydrophobicContact CG2-CG2 4.01Å
292E88.7Confident81.6Confident60 Ų6057.4 Ų57.428%0.2830%0.304SS..EExtended strand (participates in β ladder)trans-127.7148.5178.6-67.4-157.6175.100112.1L345 I352E292-L345 PolarHBondContact N-O 2.97Å; E292-L345 PolarHBondContact O-N 3.44Å; E292-I352 HydrophobicContact CB-CD1 4.43Å; E292-I352 HydrophobicContact CB-CG2 3.93Å; E292-I352 HydrophobicContact CG-CD1 4.31Å; E292-I352 HydrophobicContact CG-CG2 4.23Å
293R88.7Confident80.8Confident141 Ų14159.8 Ų59.853%0.53233%0.33SS..EExtended strand (participates in β ladder)trans-97.5118176.3-50.9-168.671-172.9-2.9108.6I342 L343 N344R293-I342 HydrophobicContact CB-CG2 4.02Å; R293-L343 WeakPolarHBondContact CA-O 3.42Å; R293-N344 WeakPolarHBondContact CG-OD1 3.47Å; R293-N344 PolarHBondContact NE-OD1 3.32Å
294V89.8Confident80.8Confident0 Ų062.4 Ų62.40%034%0.335CS..EExtended strand (participates in β ladder)trans-116134.8179.4174.20000109.3L343 L345 A356 L359 G360 N361V294-L343 PolarHBondContact N-O 2.88Å; V294-L343 PolarHBondContact O-N 2.89Å; V294-L345 HydrophobicContact CB-CD1 3.93Å; V294-L345 HydrophobicContact CB-CG 4.28Å; V294-L345 HydrophobicContact CG2-CD1 3.51Å; V294-L345 HydrophobicContact CG2-CG 4.09Å; V294-A356 HydrophobicContact CG1-CB 4.14Å; V294-A356 HydrophobicContact CG2-CB 3.97Å; V294-L359 HydrophobicContact CB-CD1 4.47Å; V294-L359 HydrophobicContact CG1-CB 4.09Å; V294-L359 HydrophobicContact CG1-CD1 3.91Å; V294-G360 VanDerWaalsContact CG1-O 3.26Å; V294-G360 WeakPolarHBondContact CG1-O 2.96Å; V294-N361 HydrophobicContact CG1-CB 4.11Å
295V85.5Confident81Confident13 Ų1367 Ų678%0.07935%0.35CS..EExtended strand (participates in β ladder)trans-98.4127.9177.8-161.30000110.7T297 D341 I342 N361 Q363 L366V295-T297 PolarHBondContact O-N 3.35Å; V295-D341 WeakPolarHBondContact CA-O 3.45Å; V295-D341 WeakPolarHBondContact CG1-O 3.46Å; V295-I342 HydrophobicContact CG1-CG1 4.32Å; V295-I342 HydrophobicContact CG2-CG1 4.27Å; V295-N361 PolarHBondContact N-OD1 2.91Å; V295-Q363 HydrophobicContact CG2-CG 4.39Å; V295-L366 HydrophobicContact CB-CD1 3.91Å; V295-L366 HydrophobicContact CG1-CD1 3.35Å; V295-L366 HydrophobicContact CG2-CD1 4.39Å
296V85.5Confident81.5Confident0 Ų059.1 Ų59.10%032%0.316CS..  trans-68.9114.3178.7-1760000109.4V301 L302 L337 G340 D341 L343 L359V296-V301 HydrophobicContact CG1-CG2 3.72Å; V296-L302 HydrophobicContact CG1-CD2 3.74Å; V296-L337 HydrophobicContact CG1-CB 4.41Å; V296-L337 HydrophobicContact CG2-CD1 4.36Å; V296-L337 HydrophobicContact CG2-CD2 4.36Å; V296-G340 PolarHBondContact O-N 3.29Å; V296-D341 HydrophobicContact CB-CB 4.28Å; V296-D341 HydrophobicContact CG2-CB 3.88Å; V296-D341 PolarHBondContact N-O 3.44Å; V296-L343 HydrophobicContact CG2-CD1 3.6Å; V296-L343 HydrophobicContact CG2-CD2 4.4Å; V296-L343 HydrophobicContact CG2-CG 3.8Å; V296-L359 HydrophobicContact CG2-CD2 4.34Å
297T78.4Confident82.1Confident3 Ų360.6 Ų60.62%0.01829%0.294CS..  trans-134.6-9.8-177.653.90000113.4V295 F339 L359 G360 N361 A362 L366V295-T297 PolarHBondContact O-N 3.35Å; T297-F339 HydrophobicContact CG2-CE2 4.34Å; T297-L359 PolarHBondContact N-O 2.85Å; T297-G360 WeakPolarHBondContact OG1-CA 3.29Å; T297-N361 PolarHBondContact OG1-N 3.25Å; T297-A362 PolarHBondContact OG1-N 3.49Å; T297-A362 VanDerWaalsContact OG1-N 3.12Å; T297-L366 HydrophobicContact CG2-CD1 3.86Å; T297-L366 HydrophobicContact CG2-CD2 4.43Å; T297-L366 HydrophobicContact CG2-CG 3.92Å
298N79Confident82.2Confident45 Ų4562.2 Ų62.224%0.24130%0.3CS..  trans-86.2125.7-179.8-170.7-15.9000111.3N300 V301 L302 V358 L359N298-N300 PolarHBondContact O-N 3.17Å; N298-N300 PolarHBondContact OD1-N 2.88Å; N298-N300 VanDerWaalsContact OD1-N 3.11Å; N298-V301 HydrophobicContact CB-CG2 4.28Å; N298-V301 WeakPolarHBondContact O-CG2 3.28Å; N298-V301 PolarHBondContact O-N 2.94Å; N298-L302 WeakPolarHBondContact O-CG 3.39Å; N298-V358 WeakPolarHBondContact CB-O 3.3Å; N298-V358 PolarHBondContact ND2-O 2.96Å; N298-L359 VanDerWaalsContact CB-C 3.43Å; N298-L359 VanDerWaalsContact CB-O 3.27Å; N298-L359 WeakPolarHBondContact CB-O 3.27Å; N298-L359 PolarHBondContact N-O 3.19Å
299E70.3Confident82.4Confident72 Ų7258.9 Ų58.934%0.33628%0.282SS..G310 helixtrans-55.8-36.3179.3-69173.8-155.300112.8V301 L302 Y423E299-V301 PolarHBondContact O-N 2.72Å; E299-V301 VanDerWaalsContact O-N 3.13Å; E299-L302 PolarHBondContact O-N 2.98Å; E299-Y423 HydrophobicContact CG-CE1 4.43Å; E299-Y423 HydrophobicContact CG-CE2 4.41Å; E299-Y423 WeakPolarHBondContact CG-OH 3.46Å; E299-Y423 VanDerWaalsContact OE1-CE2 3.3Å; E299-Y423 WeakPolarHBondContact OE1-CE2 3.37Å; E299-Y423 VanDerWaalsContact OE1-CZ 3.28Å; E299-Y423 PolarHBondContact OE1-OH 3.3Å
300N77Confident82.3Confident115 Ų11563.4 Ų63.462%0.61530%0.303SS*.G310 helixtrans-69.7-13.8-172.2-66.1-26.6000113.6N298 K304N298-N300 PolarHBondContact O-N 3.17Å; N298-N300 PolarHBondContact OD1-N 2.88Å; N298-N300 VanDerWaalsContact OD1-N 3.11Å; N300-K304 WeakPolarHBondContact O-CD 3.42Å; N300-K304 WeakPolarHBondContact O-CE 3.23Å; N300-K304 PolarHBondContact O-NZ 3.47Å
301V79.5Confident82.3Confident3 Ų357.2 Ų57.22%0.01828%0.28CS..G310 helixtrans-106.9-8.7177.6-580000113.3V296 N298 E299 K304 L309 L337 V358 L359V296-V301 HydrophobicContact CG1-CG2 3.72Å; N298-V301 HydrophobicContact CB-CG2 4.28Å; N298-V301 WeakPolarHBondContact O-CG2 3.28Å; N298-V301 PolarHBondContact O-N 2.94Å; E299-V301 PolarHBondContact O-N 2.72Å; E299-V301 VanDerWaalsContact O-N 3.13Å; V301-K304 PolarHBondContact O-N 3.27Å; V301-L309 HydrophobicContact CB-CD1 4.48Å; V301-L309 HydrophobicContact CB-CD2 4.38Å; V301-L309 HydrophobicContact CG1-CD2 4.03Å; V301-L337 HydrophobicContact CB-CD1 4.36Å; V301-L337 HydrophobicContact CG2-CD1 4.39Å; V301-V358 HydrophobicContact CG1-CG1 3.88Å; V301-V358 WeakPolarHBondContact CG1-O 3.35Å; V301-L359 HydrophobicContact CG2-CD2 4.32Å
302L71.1Confident82.1Confident39 Ų3956 Ų5620%0.20427%0.269CS..THydrogen-bonded Turntrans-67.1135.4-179-58.3-176000110.8V296 N298 E299 K304 F339 Y423V296-L302 HydrophobicContact CG1-CD2 3.74Å; N298-L302 WeakPolarHBondContact O-CG 3.39Å; E299-L302 PolarHBondContact O-N 2.98Å; L302-K304 PolarHBondContact O-N 3.4Å; L302-F339 HydrophobicContact CD1-CB 4.06Å; L302-F339 HydrophobicContact CD1-CD2 4.32Å; L302-F339 HydrophobicContact CD2-CB 3.94Å; L302-Y423 HydrophobicContact CD1-CE1 4.06Å
303G65.2Low81.8Confident56 Ų5658.2 Ų58.258%0.57728%0.279SS*.THydrogen-bonded Turntrans77.2-13.8-178.100000115.1S336 L337G303-S336 WeakPolarHBondContact O-CB 3.27Å; G303-L337 PolarHBondContact N-O 3.46Å
304K77.3Confident81.7Confident101 Ų10160.3 Ų60.344%0.43929%0.287SS..  trans-73.6144.3174.5-65.8-173.7176.6164.50110.9N300 V301 L302 L309 S336 L337N300-K304 WeakPolarHBondContact O-CD 3.42Å; N300-K304 WeakPolarHBondContact O-CE 3.23Å; N300-K304 PolarHBondContact O-NZ 3.47Å; V301-K304 PolarHBondContact O-N 3.27Å; L302-K304 PolarHBondContact O-N 3.4Å; K304-L309 HydrophobicContact CB-CD2 4.23Å; K304-L309 HydrophobicContact CB-CG 4.44Å; K304-L309 HydrophobicContact CD-CD2 3.88Å; K304-S336 VanDerWaalsContact O-CA 3.3Å; K304-S336 WeakPolarHBondContact O-CA 3.07Å; K304-L337 PolarHBondContact O-N 3.32Å
305R78.6Confident81.6Confident121 Ų12162.9 Ų62.946%0.45730%0.297SS..BIsolated β-bridgetrans-73.4149.9173.5-58.2-178.6177.8-160.45.6110R307 D308 G333 D334 I335R305-R307 PolarHBondContact O-N 3.38Å; R305-D308 WeakPolarHBondContact CB-OD2 3.47Å; R305-D308 PolarHBondContact O-N 3.48Å; R305-D308 VanDerWaalsContact O-N 3.15Å; R305-G333 WeakPolarHBondContact CB-O 3.18Å; R305-D334 IonicContact NH1-OD1 4Å; R305-D334 PolarHBondContact NH1-OD1 3.4Å; R305-I335 WeakPolarHBondContact CA-O 3.46Å
306I86.7Confident81.8Confident19 Ų1965.2 Ų65.210%0.09731%0.309CS..THydrogen-bonded Turntrans-56.3-41.1177.1-73174.6000111.3D308 L309 I319 L322 A331 G333 I335 L337I306-D308 VanDerWaalsContact C-N 3.31Å; I306-D308 PolarHBondContact O-N 2.61Å; I306-L309 PolarHBondContact O-N 2.91Å; I306-I319 HydrophobicContact CD1-CD1 4.11Å; I306-I319 HydrophobicContact CG1-CD1 4.1Å; I306-I319 HydrophobicContact CG2-CD1 3.83Å; I306-L322 HydrophobicContact CD1-CD1 4.3Å; I306-A331 HydrophobicContact CD1-CB 3.99Å; I306-G333 PolarHBondContact N-O 2.92Å; I306-I335 HydrophobicContact CD1-CB 4.37Å; I306-I335 PolarHBondContact N-O 3.32Å; I306-L337 HydrophobicContact CD1-CD2 4.13Å; I306-L337 HydrophobicContact CG1-CD2 3.81Å; I306-L337 HydrophobicContact CG1-CG 4.22Å
307R84Confident82.2Confident122 Ų12265.2 Ų65.246%0.4631%0.31SS..G310 helixtrans-59.6-40.1178.5-170.4176.9-65.2157.95.1112.3D230 R305 L309 H310 G333 D334D230-R307 IonicContact OD1-NH2 3.52Å; D230-R307 PolarHBondContact OD1-NH2 3.34Å; D230-R307 IonicContact OD2-CZ 2.84Å; D230-R307 IonicContact OD2-NH2 3.66Å; D230-R307 PolarHBondContact OD2-NH2 2.95Å; R305-R307 PolarHBondContact O-N 3.38Å; R307-L309 PolarHBondContact O-N 3.44Å; R307-H310 PolarHBondContact O-N 3.38Å; R307-G333 WeakPolarHBondContact CB-O 3.47Å; R307-G333 PolarHBondContact N-O 3.21Å; R307-D334 IonicContact NH1-OD1 3.57Å
308D85.7Confident82.9Confident89 Ų8965.5 Ų65.548%0.47631%0.311SS..G310 helixtrans-69.9-14.4-176.9-54.1-24.8000113R305 I306 H310R305-D308 WeakPolarHBondContact CB-OD2 3.47Å; R305-D308 PolarHBondContact O-N 3.48Å; R305-D308 VanDerWaalsContact O-N 3.15Å; I306-D308 VanDerWaalsContact C-N 3.31Å; I306-D308 PolarHBondContact O-N 2.61Å; D308-H310 VanDerWaalsContact C-ND1 3.32Å; D308-H310 PolarHBondContact O-CE1 3.44Å; D308-H310 VanDerWaalsContact O-CE1 3.26Å; D308-H310 PolarHBondContact O-ND1 2.91Å
309L89.5Confident83.6Confident22 Ų2263.8 Ų63.812%0.11530%0.302CS..G310 helixtrans-87.5-16.2178.9-62.6168.8000112.7V301 K304 I306 R307 F311 L337V301-L309 HydrophobicContact CB-CD1 4.48Å; V301-L309 HydrophobicContact CB-CD2 4.38Å; V301-L309 HydrophobicContact CG1-CD2 4.03Å; K304-L309 HydrophobicContact CB-CD2 4.23Å; K304-L309 HydrophobicContact CB-CG 4.44Å; K304-L309 HydrophobicContact CD-CD2 3.88Å; I306-L309 PolarHBondContact O-N 2.91Å; R307-L309 PolarHBondContact O-N 3.44Å; L309-F311 HydrophobicContact CB-CD1 4.3Å; L309-F311 HydrophobicContact CB-CD2 3.86Å; L309-F311 HydrophobicContact CB-CE1 4.01Å; L309-F311 HydrophobicContact CB-CE2 3.53Å; L309-F311 HydrophobicContact CB-CG 4.24Å; L309-F311 HydrophobicContact CB-CZ 3.62Å; L309-F311 HydrophobicContact CD1-CD2 4.39Å; L309-F311 HydrophobicContact CD1-CE2 3.42Å; L309-F311 VanDerWaalsContact CD1-CE2 3.42Å; L309-F311 HydrophobicContact CD1-CZ 3.63Å; L309-F311 HydrophobicContact CD2-CZ 4.37Å; L309-F311 HydrophobicContact CG-CE2 4.06Å; L309-F311 HydrophobicContact CG-CZ 4.06Å; L309-F311 PolarHBondContact O-N 3.23Å; L309-F311 VanDerWaalsContact O-N 3.16Å; L309-L337 HydrophobicContact CD1-CD1 3.44Å; L309-L337 VanDerWaalsContact CD1-CD1 3.44Å; L309-L337 HydrophobicContact CD1-CG 4.33Å
310H88.3Confident84.5Confident102 Ų10260.7 Ų60.747%0.47229%0.288SS..THydrogen-bonded Turntrans51.337.2174.4-52.489.1000113.8R307 D308 K312 E313 R314R307-H310 PolarHBondContact O-N 3.38Å; D308-H310 VanDerWaalsContact C-ND1 3.32Å; D308-H310 PolarHBondContact O-CE1 3.44Å; D308-H310 VanDerWaalsContact O-CE1 3.26Å; D308-H310 PolarHBondContact O-ND1 2.91Å; H310-K312 VanDerWaalsContact C-N 3.25Å; H310-K312 PolarHBondContact O-N 3.45Å; H310-E313 VanDerWaalsContact C-OE2 3.3Å; H310-E313 VanDerWaalsContact CA-OE2 3.23Å; H310-E313 WeakPolarHBondContact CA-OE2 3.41Å; H310-E313 PolarHBondContact O-N 3.25Å; H310-R314 WeakPolarHBondContact O-CB 3.48Å; H310-R314 PolarHBondContact O-N 2.97Å
311F90Very high85.1Confident9 Ų958.1 Ų58.14%0.03927%0.27CS..Hα-helixtrans-64.2-32.9-175.6-66.6-48.9000113.1L309 Y315 V317 I319 V355 V358 L359L309-F311 HydrophobicContact CB-CD1 4.3Å; L309-F311 HydrophobicContact CB-CD2 3.86Å; L309-F311 HydrophobicContact CB-CE1 4.01Å; L309-F311 HydrophobicContact CB-CE2 3.53Å; L309-F311 HydrophobicContact CB-CG 4.24Å; L309-F311 HydrophobicContact CB-CZ 3.62Å; L309-F311 HydrophobicContact CD1-CD2 4.39Å; L309-F311 HydrophobicContact CD1-CE2 3.42Å; L309-F311 VanDerWaalsContact CD1-CE2 3.42Å; L309-F311 HydrophobicContact CD1-CZ 3.63Å; L309-F311 HydrophobicContact CD2-CZ 4.37Å; L309-F311 HydrophobicContact CG-CE2 4.06Å; L309-F311 HydrophobicContact CG-CZ 4.06Å; L309-F311 PolarHBondContact O-N 3.23Å; L309-F311 VanDerWaalsContact O-N 3.16Å; F311-Y315 HydrophobicContact CD1-CD2 4.04Å; F311-Y315 HydrophobicContact CD1-CE2 4.21Å; F311-Y315 WeakPolarHBondContact O-CB 3.36Å; F311-Y315 PolarHBondContact O-N 3.19Å; F311-V317 CarbonylContact C-O 3.55Å; F311-V317 PolarHBondContact O-N 3.37Å; F311-I319 HydrophobicContact CD2-CD1 3.8Å; F311-I319 HydrophobicContact CD2-CG1 4.49Å; F311-I319 HydrophobicContact CE2-CD1 4.1Å; F311-V355 HydrophobicContact CB-CG2 4.39Å; F311-V355 HydrophobicContact CD1-CB 4.38Å; F311-V355 HydrophobicContact CD1-CG1 3.77Å; F311-V355 HydrophobicContact CD1-CG2 3.82Å; F311-V355 HydrophobicContact CD2-CG1 4.3Å; F311-V355 HydrophobicContact CE1-CG1 3.86Å; F311-V355 HydrophobicContact CE1-CG2 4.43Å; F311-V355 HydrophobicContact CE2-CG1 4.36Å; F311-V355 HydrophobicContact CG-CG1 4Å; F311-V355 HydrophobicContact CG-CG2 4.32Å; F311-V355 HydrophobicContact CZ-CG1 4.15Å; F311-V358 HydrophobicContact CE1-CB 4.19Å; F311-V358 HydrophobicContact CE1-CG1 3.85Å; F311-V358 HydrophobicContact CZ-CG1 4.18Å; F311-L359 HydrophobicContact CE2-CD2 3.74Å; F311-L359 HydrophobicContact CE2-CG 4.29Å; F311-L359 HydrophobicContact CZ-CD2 3.59Å; F311-L359 HydrophobicContact CZ-CG 3.91Å
312K84.4Confident85.3Confident43 Ų4358 Ų5819%0.18727%0.269CS..Hα-helixtrans-70.6-45.2-178-167.5175.8179.7-177.80110.9P246 H310 D316 V317 V318P246-K312 WeakPolarHBondContact O-CE 3.48Å; P246-K312 PolarHBondContact O-NZ 2.74Å; H310-K312 VanDerWaalsContact C-N 3.25Å; H310-K312 PolarHBondContact O-N 3.45Å; K312-D316 WeakPolarHBondContact O-CA 3.16Å; K312-D316 PolarHBondContact O-N 3.14Å; K312-V317 VanDerWaalsContact CA-O 3.26Å; K312-V317 WeakPolarHBondContact CA-O 3.22Å; K312-V317 PolarHBondContact N-O 3.24Å; K312-V318 HydrophobicContact CD-CG2 4.48Å
313E83.8Confident85.5Confident107 Ų10757.5 Ų57.550%0.527%0.267SS..Hα-helixtrans-76.3-36.1-179.4-58.277.7-168.400112.2P248 H310P248-E313 HydrophobicContact CG-CG 4.15Å; P248-E313 WeakPolarHBondContact CG-OE1 3.4Å; H310-E313 VanDerWaalsContact C-OE2 3.3Å; H310-E313 VanDerWaalsContact CA-OE2 3.23Å; H310-E313 WeakPolarHBondContact CA-OE2 3.41Å; H310-E313 PolarHBondContact O-N 3.25Å
314R86.3Confident85.6Confident186 Ų18657.4 Ų57.470%0.70225%0.249SC*.Hα-helixtrans-90-28.9-172.6-167.2174.1-176.1-176.83.4114.1H310H310-R314 WeakPolarHBondContact O-CB 3.48Å; H310-R314 PolarHBondContact O-N 2.97Å
315Y88.1Confident84.7Confident53 Ų5357.8 Ų57.821%0.20827%0.271CS..Hα-helixtrans-129.6-1.1-171.8-58.8-82.9000114.2F311 V317 A351 A354 V355F311-Y315 HydrophobicContact CD1-CD2 4.04Å; F311-Y315 HydrophobicContact CD1-CE2 4.21Å; F311-Y315 WeakPolarHBondContact O-CB 3.36Å; F311-Y315 PolarHBondContact O-N 3.19Å; Y315-V317 PolarHBondContact O-N 2.9Å; Y315-A351 WeakPolarHBondContact O-CB 3Å; Y315-A354 HydrophobicContact CD1-CB 3.77Å; Y315-A354 HydrophobicContact CE1-CB 3.89Å; Y315-V355 HydrophobicContact CD1-CG2 4.31Å; Y315-V355 HydrophobicContact CD2-CG2 3.67Å; Y315-V355 HydrophobicContact CE2-CG2 4.42Å; Y315-V355 HydrophobicContact CG-CG2 3.6Å
316D89.2Confident83.6Confident62 Ų6255 Ų5533%0.33228%0.28SS..SBendtrans5635.2-170-57.4-40.2000113.2K312 R348K312-D316 WeakPolarHBondContact O-CA 3.16Å; K312-D316 PolarHBondContact O-N 3.14Å; D316-R348 IonicContact OD2-CZ 2.91Å; D316-R348 IonicContact OD2-NH2 3.72Å; D316-R348 PolarHBondContact OD2-NH2 3.18Å
317V93.2Very high82Confident1 Ų157.9 Ų57.91%0.00630%0.298CS..  trans-116130.3176.9179.10000109.9F311 K312 Y315 L345 V346 A351 I352 V355F311-V317 CarbonylContact C-O 3.55Å; F311-V317 PolarHBondContact O-N 3.37Å; K312-V317 VanDerWaalsContact CA-O 3.26Å; K312-V317 WeakPolarHBondContact CA-O 3.22Å; K312-V317 PolarHBondContact N-O 3.24Å; Y315-V317 PolarHBondContact O-N 2.9Å; V317-L345 HydrophobicContact CG1-CB 3.9Å; V317-L345 HydrophobicContact CG1-CD1 4.34Å; V317-L345 HydrophobicContact CG1-CD2 4.2Å; V317-L345 HydrophobicContact CG1-CG 4.38Å; V317-V346 WeakPolarHBondContact CA-O 3.37Å; V317-A351 HydrophobicContact CG2-CB 3.72Å; V317-I352 HydrophobicContact CG2-CG1 4.47Å; V317-V355 HydrophobicContact CB-CG2 3.89Å; V317-V355 HydrophobicContact CG1-CB 4.46Å; V317-V355 HydrophobicContact CG1-CG1 4.4Å; V317-V355 HydrophobicContact CG1-CG2 4.3Å; V317-V355 HydrophobicContact CG2-CB 4.38Å; V317-V355 HydrophobicContact CG2-CG2 3.73Å
318V93.6Very high81.4Confident9 Ų955.3 Ų55.36%0.05529%0.291CS..EExtended strand (participates in β ladder)trans-110.2135.5173.173.80000110.2I233 S235 V245 K312 S320 V346I233-V318 HydrophobicContact CG2-CG2 3.59Å; S235-V318 WeakPolarHBondContact O-CG1 3.29Å; V245-V318 HydrophobicContact CG1-CB 4.01Å; V245-V318 HydrophobicContact CG1-CG1 4.08Å; K312-V318 HydrophobicContact CD-CG2 4.48Å; V318-S320 PolarHBondContact O-N 2.84Å; V318-V346 HydrophobicContact CG1-CB 3.86Å; V318-V346 HydrophobicContact CG1-CG2 4.46Å; V318-V346 PolarHBondContact N-O 3.41Å; V318-V346 PolarHBondContact O-N 3.33Å
319I93.4Very high80.9Confident8 Ų854 Ų544%0.04128%0.284CS..EExtended strand (participates in β ladder)trans-85.2106.8169.5-55.4167.3000106.3I306 F311 A331 L343 L345I306-I319 HydrophobicContact CD1-CD1 4.11Å; I306-I319 HydrophobicContact CG1-CD1 4.1Å; I306-I319 HydrophobicContact CG2-CD1 3.83Å; F311-I319 HydrophobicContact CD2-CD1 3.8Å; F311-I319 HydrophobicContact CD2-CG1 4.49Å; F311-I319 HydrophobicContact CE2-CD1 4.1Å; I319-A331 HydrophobicContact CB-CB 3.93Å; I319-A331 HydrophobicContact CG2-CB 3.4Å; I319-A331 WeakPolarHBondContact O-CB 3.47Å; I319-L343 HydrophobicContact CD1-CD1 3.99Å; I319-L343 HydrophobicContact CG2-CB 4.07Å; I319-L343 HydrophobicContact CG2-CD2 4.24Å; I319-L345 HydrophobicContact CB-CD2 4.39Å; I319-L345 HydrophobicContact CG1-CD2 3.59Å
320S90.6Very high80.6Confident7 Ų753.8 Ų53.85%0.04928%0.284CS..EExtended strand (participates in β ladder)trans-77.4-37.2-177.560.10000112.4V318 N344V318-S320 PolarHBondContact O-N 2.84Å; S320-N344 PolarHBondContact N-O 3.44Å; S320-N344 WeakPolarHBondContact OG-CB 3.4Å; S320-N344 PolarHBondContact OG-O 3.46Å
321R88.4Confident80.5Confident61 Ų6149.1 Ų49.123%0.2326%0.262CS..EExtended strand (participates in β ladder)trans-150.6152.1-175.1-53.3-178-163.4171.30.5110.2I204 V261 E328 L329 N344I204-R321 HydrophobicContact CG2-CG 4.25Å; V261-R321 HydrophobicContact CG1-CG 3.83Å; R321-E328 HydrophobicContact CB-CG 4.16Å; R321-E328 WeakPolarHBondContact CD-OE1 3.37Å; R321-E328 IonicContact CZ-OE1 3.37Å; R321-E328 IonicContact NE-OE1 3.83Å; R321-E328 IonicContact NH1-OE1 3.53Å; R321-E328 PolarHBondContact NH1-OE1 3Å; R321-E328 IonicContact NH1-OE2 2.8Å; R321-L329 WeakPolarHBondContact CA-O 3.29Å; R321-N344 HydrophobicContact CB-CB 4.2Å; R321-N344 PolarHBondContact O-N 3.06Å
322L83.6Confident80.1Confident0 Ų049.7 Ų49.70%027%0.268CS..EExtended strand (participates in β ladder)trans-124.7125.7175.2174.9148.3000108.4I306 R324 E328 L329 A331 I335 L337 D341 L343I306-L322 HydrophobicContact CD1-CD1 4.3Å; L322-R324 HydrophobicContact CD2-CB 3.86Å; L322-E328 CarbonylContact O-C 3.58Å; L322-E328 WeakPolarHBondContact O-CA 3.4Å; L322-L329 HydrophobicContact CD2-CB 4.25Å; L322-L329 HydrophobicContact CD2-CD1 3.8Å; L322-L329 HydrophobicContact CD2-CG 4.43Å; L322-L329 PolarHBondContact N-O 2.92Å; L322-L329 PolarHBondContact O-N 3.29Å; L322-A331 HydrophobicContact CB-CB 4.22Å; L322-I335 HydrophobicContact CD1-CG2 3.85Å; L322-L337 HydrophobicContact CD1-CD2 4.04Å; L322-D341 HydrophobicContact CD1-CB 4.46Å; L322-L343 HydrophobicContact CB-CD2 3.95Å; L322-L343 HydrophobicContact CD1-CD2 3.5Å; L322-L343 HydrophobicContact CG-CD2 3.71Å
323N74.6Confident79.8Confident30 Ų3048.2 Ų48.216%0.1626%0.264CS..EExtended strand (participates in β ladder)trans-104.4119.9171-172.3-52.8000109.4G326 V327 I342N323-G326 VanDerWaalsContact OD1-CA 3.22Å; N323-G326 WeakPolarHBondContact OD1-CA 3.2Å; N323-G326 PolarHBondContact OD1-N 3.22Å; N323-V327 VanDerWaalsContact CA-O 3.3Å; N323-V327 WeakPolarHBondContact CA-O 3.38Å; N323-I342 HydrophobicContact CB-CB 4.23Å; N323-I342 PolarHBondContact N-O 3.41Å; N323-I342 PolarHBondContact O-N 2.95Å
324R68.5Low79.3Confident54 Ų5446.4 Ų46.420%0.20426%0.258CS..EExtended strand (participates in β ladder)trans-121.3118.8176.9-178.5172.4-66.2167.81.3109.1L322 G326 V327 S336 Q338 D341L322-R324 HydrophobicContact CD2-CB 3.86Å; R324-G326 PolarHBondContact O-N 2.91Å; R324-G326 VanDerWaalsContact O-N 3.1Å; R324-V327 PolarHBondContact N-O 3.21Å; R324-V327 PolarHBondContact O-N 3.33Å; R324-S336 PolarHBondContact NH2-O 2.72Å; R324-Q338 VanDerWaalsContact CZ-CD 3.47Å; R324-D341 WeakPolarHBondContact CB-OD1 3.31Å; R324-D341 WeakPolarHBondContact CG-OD1 3Å; R324-D341 IonicContact CZ-OD1 3.77Å; R324-D341 IonicContact CZ-OD2 3.99Å; R324-D341 IonicContact NE-OD1 3.66Å; R324-D341 PolarHBondContact NE-OD1 2.99Å; R324-D341 IonicContact NE-OD2 2.66Å; R324-D341 IonicContact NH2-OD1 3.66Å; R324-D341 IonicContact NH2-OD2 2.92Å; R324-D341 PolarHBondContact NH2-OD2 3.41Å
325A58.2Low78.7Confident108 Ų10839 Ų3989%0.89323%0.232SC*.THydrogen-bonded Turntrans49.736.8179.500000113.7
326G55Low78.1Confident63 Ų6338.8 Ų38.865%0.64924%0.239SC*.THydrogen-bonded Turntrans90.2-7.1178.500000115.3N323 R324N323-G326 VanDerWaalsContact OD1-CA 3.22Å; N323-G326 WeakPolarHBondContact OD1-CA 3.2Å; N323-G326 PolarHBondContact OD1-N 3.22Å; R324-G326 PolarHBondContact O-N 2.91Å; R324-G326 VanDerWaalsContact O-N 3.1Å
327V53.5Low77.6Confident80 Ų8035.9 Ų35.949%0.48522%0.223SC..EExtended strand (participates in β ladder)trans-96.7125.8175.5-175.80000109.7N323 R324 L329N323-V327 VanDerWaalsContact CA-O 3.3Å; N323-V327 WeakPolarHBondContact CA-O 3.38Å; R324-V327 PolarHBondContact N-O 3.21Å; R324-V327 PolarHBondContact O-N 3.33Å; V327-L329 HydrophobicContact CG1-CD2 3.98Å; V327-L329 HydrophobicContact CG1-CG 4.41Å
328E70.7Confident76.6Confident67 Ų6740 Ų4031%0.31324%0.242SC..EExtended strand (participates in β ladder)trans-88.1128.2176-161169.7-160.300110.3I204 R321 L322I204-E328 HydrophobicContact CG1-CG 4.46Å; R321-E328 HydrophobicContact CB-CG 4.16Å; R321-E328 WeakPolarHBondContact CD-OE1 3.37Å; R321-E328 IonicContact CZ-OE1 3.37Å; R321-E328 IonicContact NE-OE1 3.83Å; R321-E328 IonicContact NH1-OE1 3.53Å; R321-E328 PolarHBondContact NH1-OE1 3Å; R321-E328 IonicContact NH1-OE2 2.8Å; L322-E328 CarbonylContact O-C 3.58Å; L322-E328 WeakPolarHBondContact O-CA 3.4Å
329L75.4Confident75.7Confident62 Ų6241.7 Ų41.733%0.32525%0.249SC..EExtended strand (participates in β ladder)trans-125.1151-173.4-60.3173.8000109.9R321 L322 V327 A331R321-L329 WeakPolarHBondContact CA-O 3.29Å; L322-L329 HydrophobicContact CD2-CB 4.25Å; L322-L329 HydrophobicContact CD2-CD1 3.8Å; L322-L329 HydrophobicContact CD2-CG 4.43Å; L322-L329 PolarHBondContact N-O 2.92Å; L322-L329 PolarHBondContact O-N 3.29Å; V327-L329 HydrophobicContact CG1-CD2 3.98Å; V327-L329 HydrophobicContact CG1-CG 4.41Å; L329-A331 PolarHBondContact O-N 3.05Å
330V83.7Confident74.8Confident18 Ų1842.5 Ų42.511%0.10926%0.259CS..EExtended strand (participates in β ladder)trans-63.1128.6164.6-175.50000106.1I204 I233 S332 I335I204-V330 HydrophobicContact CD1-CB 4.1Å; I204-V330 HydrophobicContact CD1-CG2 3.22Å; I233-V330 HydrophobicContact CD1-CG1 4.39Å; I233-V330 HydrophobicContact CG1-CG1 3.68Å; V330-S332 PolarHBondContact O-N 2.8Å; V330-I335 WeakPolarHBondContact O-CD1 3.46Å
331A85.5Confident74.1Confident3 Ų342.3 Ų42.33%0.02526%0.258CS..  trans-79.165.9178.300000111I306 I319 L322 L329I306-A331 HydrophobicContact CD1-CB 3.99Å; I319-A331 HydrophobicContact CB-CB 3.93Å; I319-A331 HydrophobicContact CG2-CB 3.4Å; I319-A331 WeakPolarHBondContact O-CB 3.47Å; L322-A331 HydrophobicContact CB-CB 4.22Å; L329-A331 PolarHBondContact O-N 3.05Å
332S81.5Confident74Confident22 Ų2241.7 Ų41.715%0.15426%0.258CS..  trans-62.4152.117966.10000111.8D230 V330 D334 I335D230-S332 WeakPolarHBondContact O-CB 3.44Å; V330-S332 PolarHBondContact O-N 2.8Å; S332-D334 PolarHBondContact O-N 3.42Å; S332-D334 VanDerWaalsContact O-N 3.13Å; S332-I335 PolarHBondContact O-N 2.87Å; S332-I335 VanDerWaalsContact O-N 3.14Å; S332-I335 VanDerWaalsContact OG-CD1 3.31Å; S332-I335 WeakPolarHBondContact OG-CD1 3.47Å; S332-I335 VanDerWaalsContact OG-CG1 3.28Å; S332-I335 WeakPolarHBondContact OG-CG1 3.38Å
333G79.6Confident74.3Confident11 Ų1141.7 Ų41.711%0.11326%0.258CS..THydrogen-bonded Turntrans-59.5-30.5-176.900000113.3D230 R305 I306 R307D230-G333 PolarHBondContact OD1-N 3.36Å; R305-G333 WeakPolarHBondContact CB-O 3.18Å; I306-G333 PolarHBondContact N-O 2.92Å; R307-G333 WeakPolarHBondContact CB-O 3.47Å; R307-G333 PolarHBondContact N-O 3.21Å
334D73.6Confident75.2Confident70 Ų7041.2 Ų41.237%0.37426%0.256SS..THydrogen-bonded Turntrans-80.9-9.3-178.1-74.1-30.8000115.6R305 R307 S332 S336R305-D334 IonicContact NH1-OD1 4Å; R305-D334 PolarHBondContact NH1-OD1 3.4Å; R307-D334 IonicContact NH1-OD1 3.57Å; S332-D334 PolarHBondContact O-N 3.42Å; S332-D334 VanDerWaalsContact O-N 3.13Å; D334-S336 PolarHBondContact O-N 2.93Å
335I72.5Confident76.4Confident30 Ų3038.6 Ų38.615%0.15425%0.246CC..PPolyproline II helixtrans-70.9125.9178.7-74.7164.2000109.3R305 I306 L322 V330 S332R305-I335 WeakPolarHBondContact CA-O 3.46Å; I306-I335 HydrophobicContact CD1-CB 4.37Å; I306-I335 PolarHBondContact N-O 3.32Å; L322-I335 HydrophobicContact CD1-CG2 3.85Å; V330-I335 WeakPolarHBondContact O-CD1 3.46Å; S332-I335 PolarHBondContact O-N 2.87Å; S332-I335 VanDerWaalsContact O-N 3.14Å; S332-I335 VanDerWaalsContact OG-CD1 3.31Å; S332-I335 WeakPolarHBondContact OG-CD1 3.47Å; S332-I335 VanDerWaalsContact OG-CG1 3.28Å; S332-I335 WeakPolarHBondContact OG-CG1 3.38Å
336S76.8Confident78.1Confident49 Ų4933.6 Ų33.634%0.34320%0.204SC..BIsolated β-bridgetrans-79.1133.8168.855.40000111.1G303 K304 R324 D334G303-S336 WeakPolarHBondContact O-CB 3.27Å; K304-S336 VanDerWaalsContact O-CA 3.3Å; K304-S336 WeakPolarHBondContact O-CA 3.07Å; R324-S336 PolarHBondContact NH2-O 2.72Å; D334-S336 PolarHBondContact O-N 2.93Å
337L78.1Confident79.9Confident1 Ų130.6 Ų30.61%0.00517%0.173CC..PPolyproline II helixtrans-72.3139.8179-66.5-177.2000111.5V296 V301 G303 K304 I306 L309 L322 L343 L359V296-L337 HydrophobicContact CG1-CB 4.41Å; V296-L337 HydrophobicContact CG2-CD1 4.36Å; V296-L337 HydrophobicContact CG2-CD2 4.36Å; V301-L337 HydrophobicContact CB-CD1 4.36Å; V301-L337 HydrophobicContact CG2-CD1 4.39Å; G303-L337 PolarHBondContact N-O 3.46Å; K304-L337 PolarHBondContact O-N 3.32Å; I306-L337 HydrophobicContact CD1-CD2 4.13Å; I306-L337 HydrophobicContact CG1-CD2 3.81Å; I306-L337 HydrophobicContact CG1-CG 4.22Å; L309-L337 HydrophobicContact CD1-CD1 3.44Å; L309-L337 VanDerWaalsContact CD1-CD1 3.44Å; L309-L337 HydrophobicContact CD1-CG 4.33Å; L322-L337 HydrophobicContact CD1-CD2 4.04Å; L337-L343 HydrophobicContact CD1-CD1 4.37Å; L337-L343 HydrophobicContact CD2-CD1 3.9Å; L337-L343 HydrophobicContact CD2-CD2 4Å; L337-L359 HydrophobicContact CD1-CD2 3.66Å
338Q72Confident81.8Confident86 Ų8632.1 Ų32.140%0.40217%0.17SC..  trans-118.4153.9175.5-66.7-177.2-2.400110.6R324 G340 D341R324-Q338 VanDerWaalsContact CZ-CD 3.47Å; Q338-G340 PolarHBondContact O-N 2.96Å; Q338-D341 PolarHBondContact N-OD2 2.89Å; Q338-D341 WeakPolarHBondContact O-CB 2.98Å; Q338-D341 PolarHBondContact O-N 3Å; Q338-D341 VanDerWaalsContact O-N 3.14Å
339F74.1Confident82.7Confident45 Ų4531.1 Ų31.120%0.19717%0.17CC..THydrogen-bonded Turntrans-62.8129.9176.6-176.5-97000109.6T297 L302 L366 Y423 F425T297-F339 HydrophobicContact CG2-CE2 4.34Å; L302-F339 HydrophobicContact CD1-CB 4.06Å; L302-F339 HydrophobicContact CD1-CD2 4.32Å; L302-F339 HydrophobicContact CD2-CB 3.94Å; F339-L366 HydrophobicContact CD1-CD2 4.02Å; F339-L366 HydrophobicContact CE1-CD2 3.31Å; F339-L366 HydrophobicContact CE1-CG 4.47Å; F339-L366 HydrophobicContact CE2-CD2 4.47Å; F339-L366 HydrophobicContact CZ-CD2 3.57Å; F339-L366 HydrophobicContact CZ-CG 4.33Å; F339-Y423 HydrophobicContact CD2-CD1 4.33Å; F339-Y423 AromaticContact CD2-CE1 3.83Å; F339-Y423 HydrophobicContact CD2-CE1 3.83Å; F339-Y423 HydrophobicContact CE2-CE1 4.04Å; F339-Y423 HydrophobicContact CG-CD1 4.37Å; F339-Y423 HydrophobicContact CG-CE1 4.27Å; F339-F425 HydrophobicContact CD1-CD1 4.35Å; F339-F425 HydrophobicContact CD1-CG 4.39Å; F339-F425 AromaticContact CE1-CD1 3.84Å; F339-F425 HydrophobicContact CE1-CD1 3.84Å; F339-F425 HydrophobicContact CE1-CE1 4.32Å; F339-F425 HydrophobicContact CE1-CG 4.31Å
340G74.4Confident83.5Confident25 Ų2532.3 Ų32.326%0.25818%0.183SC..THydrogen-bonded Turntrans85.4-0.3-177.100000115.3V296 Q338 I342V296-G340 PolarHBondContact O-N 3.29Å; Q338-G340 PolarHBondContact O-N 2.96Å; G340-I342 PolarHBondContact O-N 3.27Å
341D77.5Confident83.9Confident3 Ų332 Ų322%0.01618%0.182CC..  trans-57.9136.2168.4-78.8-19.3000110V295 V296 L322 R324 Q338 L343V295-D341 WeakPolarHBondContact CA-O 3.45Å; V295-D341 WeakPolarHBondContact CG1-O 3.46Å; V296-D341 HydrophobicContact CB-CB 4.28Å; V296-D341 HydrophobicContact CG2-CB 3.88Å; V296-D341 PolarHBondContact N-O 3.44Å; L322-D341 HydrophobicContact CD1-CB 4.46Å; R324-D341 WeakPolarHBondContact CB-OD1 3.31Å; R324-D341 WeakPolarHBondContact CG-OD1 3Å; R324-D341 IonicContact CZ-OD1 3.77Å; R324-D341 IonicContact CZ-OD2 3.99Å; R324-D341 IonicContact NE-OD1 3.66Å; R324-D341 PolarHBondContact NE-OD1 2.99Å; R324-D341 IonicContact NE-OD2 2.66Å; R324-D341 IonicContact NH2-OD1 3.66Å; R324-D341 IonicContact NH2-OD2 2.92Å; R324-D341 PolarHBondContact NH2-OD2 3.41Å; Q338-D341 PolarHBondContact N-OD2 2.89Å; Q338-D341 WeakPolarHBondContact O-CB 2.98Å; Q338-D341 PolarHBondContact O-N 3Å; Q338-D341 VanDerWaalsContact O-N 3.14Å; D341-L343 HydrophobicContact CB-CD2 4.25Å
342I84.5Confident84.2Confident48 Ų4831.8 Ų31.825%0.24618%0.181CC..EExtended strand (participates in β ladder)trans-105111.5176.5-50174.2000108.2R293 V295 N323 G340R293-I342 HydrophobicContact CB-CG2 4.02Å; V295-I342 HydrophobicContact CG1-CG1 4.32Å; V295-I342 HydrophobicContact CG2-CG1 4.27Å; N323-I342 HydrophobicContact CB-CB 4.23Å; N323-I342 PolarHBondContact N-O 3.41Å; N323-I342 PolarHBondContact O-N 2.95Å; G340-I342 PolarHBondContact O-N 3.27Å
343L91.6Very high84.7Confident0 Ų035 Ų350%020%0.196CC..EExtended strand (participates in β ladder)trans-98.2130.9-177.1-53.5-174.1000110.1R293 V294 V296 I319 L322 L337 D341 L345 L359R293-L343 WeakPolarHBondContact CA-O 3.42Å; V294-L343 PolarHBondContact N-O 2.88Å; V294-L343 PolarHBondContact O-N 2.89Å; V296-L343 HydrophobicContact CG2-CD1 3.6Å; V296-L343 HydrophobicContact CG2-CD2 4.4Å; V296-L343 HydrophobicContact CG2-CG 3.8Å; I319-L343 HydrophobicContact CD1-CD1 3.99Å; I319-L343 HydrophobicContact CG2-CB 4.07Å; I319-L343 HydrophobicContact CG2-CD2 4.24Å; L322-L343 HydrophobicContact CB-CD2 3.95Å; L322-L343 HydrophobicContact CD1-CD2 3.5Å; L322-L343 HydrophobicContact CG-CD2 3.71Å; L337-L343 HydrophobicContact CD1-CD1 4.37Å; L337-L343 HydrophobicContact CD2-CD1 3.9Å; L337-L343 HydrophobicContact CD2-CD2 4Å; D341-L343 HydrophobicContact CB-CD2 4.25Å; L343-L345 HydrophobicContact CB-CD2 3.99Å; L343-L345 PolarHBondContact O-N 3.43Å; L343-L359 HydrophobicContact CD1-CD1 3.8Å; L343-L359 HydrophobicContact CD1-CD2 3.86Å; L343-L359 HydrophobicContact CD1-CG 4.47Å
344N91.9Very high85.3Confident20 Ų2035.9 Ų35.911%0.10720%0.203CC..EExtended strand (participates in β ladder)trans-91100170.8-71.7-14.1000109R293 S320 R321R293-N344 WeakPolarHBondContact CG-OD1 3.47Å; R293-N344 PolarHBondContact NE-OD1 3.32Å; S320-N344 PolarHBondContact N-O 3.44Å; S320-N344 WeakPolarHBondContact OG-CB 3.4Å; S320-N344 PolarHBondContact OG-O 3.46Å; R321-N344 HydrophobicContact CB-CB 4.2Å; R321-N344 PolarHBondContact O-N 3.06Å
345L94.5Very high86.2Confident0 Ų032.6 Ų32.60%019%0.185CC..EExtended strand (participates in β ladder)trans-85.9137.8179.3-54-171.1000110.3V291 E292 V294 V317 I319 L343 I352 V355 L359V291-L345 CarbonylContact C-O 3.55Å; V291-L345 VanDerWaalsContact CA-O 3.28Å; V291-L345 WeakPolarHBondContact CA-O 3.31Å; E292-L345 PolarHBondContact N-O 2.97Å; E292-L345 PolarHBondContact O-N 3.44Å; V294-L345 HydrophobicContact CB-CD1 3.93Å; V294-L345 HydrophobicContact CB-CG 4.28Å; V294-L345 HydrophobicContact CG2-CD1 3.51Å; V294-L345 HydrophobicContact CG2-CG 4.09Å; V317-L345 HydrophobicContact CG1-CB 3.9Å; V317-L345 HydrophobicContact CG1-CD1 4.34Å; V317-L345 HydrophobicContact CG1-CD2 4.2Å; V317-L345 HydrophobicContact CG1-CG 4.38Å; I319-L345 HydrophobicContact CB-CD2 4.39Å; I319-L345 HydrophobicContact CG1-CD2 3.59Å; L343-L345 HydrophobicContact CB-CD2 3.99Å; L343-L345 PolarHBondContact O-N 3.43Å; L345-I352 HydrophobicContact CB-CG1 4.4Å; L345-I352 HydrophobicContact CD1-CG2 4.35Å; L345-V355 HydrophobicContact CD1-CB 4.31Å; L345-V355 HydrophobicContact CD1-CG1 3.81Å; L345-L359 HydrophobicContact CD1-CD1 4.06Å; L345-L359 HydrophobicContact CD2-CD1 4.3Å
346V93.6Very high87.1Confident2 Ų231.6 Ų31.61%0.01218%0.181CC..EExtended strand (participates in β ladder)trans-123.5127171.4-171.90000108.5R236 R290 V291 V317 V318R236-V346 HydrophobicContact CG-CG1 3.91Å; R290-V346 WeakPolarHBondContact O-CA 3.18Å; V291-V346 HydrophobicContact CG1-CG2 4.26Å; V291-V346 HydrophobicContact CG2-CG1 4.32Å; V291-V346 HydrophobicContact CG2-CG2 4.01Å; V317-V346 WeakPolarHBondContact CA-O 3.37Å; V318-V346 HydrophobicContact CG1-CB 3.86Å; V318-V346 HydrophobicContact CG1-CG2 4.46Å; V318-V346 PolarHBondContact N-O 3.41Å; V318-V346 PolarHBondContact O-N 3.33Å
347G93.9Very high87.7Confident0 Ų035.4 Ų35.40%020%0.198CC..EExtended strand (participates in β ladder)trans172.4-176.2-175.600000112.2L289 R290 I352L289-G347 CarbonylContact C-O 3.59Å; L289-G347 WeakPolarHBondContact CA-O 3.5Å; R290-G347 PolarHBondContact N-O 3.4Å; R290-G347 PolarHBondContact O-N 2.91Å; G347-I352 WeakPolarHBondContact O-CD1 3.14Å
348R92.1Very high88.3Confident112 Ų11237.4 Ų37.442%0.42321%0.21SC..  trans-70.1146.2171.8-68.2179.3-74.2-172.9-3.7109.9L289 D316 S350 A351 I352L289-R348 HydrophobicContact CD2-CG 3.89Å; D316-R348 IonicContact OD2-CZ 2.91Å; D316-R348 IonicContact OD2-NH2 3.72Å; D316-R348 PolarHBondContact OD2-NH2 3.18Å; R348-S350 VanDerWaalsContact C-N 3.35Å; R348-S350 PolarHBondContact O-N 3.33Å; R348-A351 HydrophobicContact CB-CB 4.3Å; R348-A351 WeakPolarHBondContact O-CB 3.32Å; R348-A351 PolarHBondContact O-N 3.37Å; R348-I352 PolarHBondContact O-N 2.91Å
349P89.8Confident89.1Confident46 Ų4633.3 Ų33.330%0.29919%0.191SC..Hα-helixtrans-49.3-49.6-177.9-29.331.7000114.1D288 R290 A351 I352 D353D288-P349 WeakPolarHBondContact O-CD 3.45Å; R290-P349 HydrophobicContact CG-CG 4.13Å; P349-A351 VanDerWaalsContact C-N 3.29Å; P349-A351 PolarHBondContact O-N 3.4Å; P349-I352 WeakPolarHBondContact O-CB 3.46Å; P349-I352 PolarHBondContact O-N 3.01Å; P349-D353 PolarHBondContact O-N 2.93Å
350S92Very high89.4Confident88 Ų8831.8 Ų31.862%0.61519%0.188SC*.Hα-helixtrans-63.7-33179.953.50000113.6R348 A354R348-S350 VanDerWaalsContact C-N 3.35Å; R348-S350 PolarHBondContact O-N 3.33Å; S350-A354 PolarHBondContact O-N 3.28Å; S350-A354 VanDerWaalsContact O-N 3.11Å
351A93Very high89.7Confident10 Ų1033.8 Ų33.88%0.08319%0.192CC..Hα-helixtrans-73.7-40.1176.200000111.9Y315 V317 R348 P349 D353 A354 V355Y315-A351 WeakPolarHBondContact O-CB 3Å; V317-A351 HydrophobicContact CG2-CB 3.72Å; R348-A351 HydrophobicContact CB-CB 4.3Å; R348-A351 WeakPolarHBondContact O-CB 3.32Å; R348-A351 PolarHBondContact O-N 3.37Å; P349-A351 VanDerWaalsContact C-N 3.29Å; P349-A351 PolarHBondContact O-N 3.4Å; A351-D353 VanDerWaalsContact C-N 3.32Å; A351-A354 PolarHBondContact O-N 3.35Å; A351-V355 WeakPolarHBondContact O-CG2 3.39Å; A351-V355 PolarHBondContact O-N 3.37Å
352I92Very high89Confident0 Ų035.4 Ų35.40%021%0.207CC..Hα-helixtrans-59.4-45.9172.1-70.7176.1000109.7R290 E292 V317 L345 G347 R348 P349 A354 V355 A356R290-I352 HydrophobicContact CB-CD1 4.08Å; R290-I352 WeakPolarHBondContact O-CD1 3.47Å; E292-I352 HydrophobicContact CB-CD1 4.43Å; E292-I352 HydrophobicContact CB-CG2 3.93Å; E292-I352 HydrophobicContact CG-CD1 4.31Å; E292-I352 HydrophobicContact CG-CG2 4.23Å; V317-I352 HydrophobicContact CG2-CG1 4.47Å; L345-I352 HydrophobicContact CB-CG1 4.4Å; L345-I352 HydrophobicContact CD1-CG2 4.35Å; G347-I352 WeakPolarHBondContact O-CD1 3.14Å; R348-I352 PolarHBondContact O-N 2.91Å; P349-I352 WeakPolarHBondContact O-CB 3.46Å; P349-I352 PolarHBondContact O-N 3.01Å; I352-A354 VanDerWaalsContact C-N 3.32Å; I352-A354 PolarHBondContact O-N 3.32Å; I352-V355 PolarHBondContact O-N 3.25Å; I352-A356 VanDerWaalsContact O-CB 3.26Å; I352-A356 WeakPolarHBondContact O-CB 3.39Å; I352-A356 PolarHBondContact O-N 2.98Å
353D90.8Very high87.9Confident88 Ų8838.2 Ų38.247%0.47122%0.218SC..Hα-helixtrans-60.2-42177.4-69.4-31.3000111.9P349 A351 A356 N357P349-D353 PolarHBondContact O-N 2.93Å; A351-D353 VanDerWaalsContact C-N 3.32Å; D353-A356 PolarHBondContact O-N 2.81Å; D353-N357 VanDerWaalsContact O-CG 3.3Å; D353-N357 PolarHBondContact O-N 3.43Å; D353-N357 PolarHBondContact O-ND2 3.38Å; D353-N357 VanDerWaalsContact O-ND2 3.16Å
354A93Very high86.2Confident31 Ų3144.9 Ų44.926%0.25625%0.25SC..Hα-helixtrans-62.5-45.1176.500000112Y315 S350 A351 I352 N357 V358Y315-A354 HydrophobicContact CD1-CB 3.77Å; Y315-A354 HydrophobicContact CE1-CB 3.89Å; S350-A354 PolarHBondContact O-N 3.28Å; S350-A354 VanDerWaalsContact O-N 3.11Å; A351-A354 PolarHBondContact O-N 3.35Å; I352-A354 VanDerWaalsContact C-N 3.32Å; I352-A354 PolarHBondContact O-N 3.32Å; A354-N357 PolarHBondContact O-N 3.29Å; A354-V358 PolarHBondContact O-N 2.88Å
355V93.3Very high84.6Confident0 Ų049.3 Ų49.30%027%0.268CS..Hα-helixtrans-68.7-37.5176.8172.50000111.4F311 Y315 V317 L345 A351 I352 N357 V358 L359F311-V355 HydrophobicContact CB-CG2 4.39Å; F311-V355 HydrophobicContact CD1-CB 4.38Å; F311-V355 HydrophobicContact CD1-CG1 3.77Å; F311-V355 HydrophobicContact CD1-CG2 3.82Å; F311-V355 HydrophobicContact CD2-CG1 4.3Å; F311-V355 HydrophobicContact CE1-CG1 3.86Å; F311-V355 HydrophobicContact CE1-CG2 4.43Å; F311-V355 HydrophobicContact CE2-CG1 4.36Å; F311-V355 HydrophobicContact CG-CG1 4Å; F311-V355 HydrophobicContact CG-CG2 4.32Å; F311-V355 HydrophobicContact CZ-CG1 4.15Å; Y315-V355 HydrophobicContact CD1-CG2 4.31Å; Y315-V355 HydrophobicContact CD2-CG2 3.67Å; Y315-V355 HydrophobicContact CE2-CG2 4.42Å; Y315-V355 HydrophobicContact CG-CG2 3.6Å; V317-V355 HydrophobicContact CB-CG2 3.89Å; V317-V355 HydrophobicContact CG1-CB 4.46Å; V317-V355 HydrophobicContact CG1-CG1 4.4Å; V317-V355 HydrophobicContact CG1-CG2 4.3Å; V317-V355 HydrophobicContact CG2-CB 4.38Å; V317-V355 HydrophobicContact CG2-CG2 3.73Å; L345-V355 HydrophobicContact CD1-CB 4.31Å; L345-V355 HydrophobicContact CD1-CG1 3.81Å; A351-V355 WeakPolarHBondContact O-CG2 3.39Å; A351-V355 PolarHBondContact O-N 3.37Å; I352-V355 PolarHBondContact O-N 3.25Å; V355-N357 VanDerWaalsContact C-N 3.3Å; V355-N357 PolarHBondContact O-N 3.47Å; V355-V358 PolarHBondContact O-N 2.71Å; V355-V358 VanDerWaalsContact O-N 3.1Å; V355-L359 HydrophobicContact CG1-CD1 3.62Å; V355-L359 HydrophobicContact CG1-CG 4.1Å; V355-L359 WeakPolarHBondContact O-CB 3.4Å; V355-L359 WeakPolarHBondContact O-CG 3.48Å; V355-L359 PolarHBondContact O-N 3.4Å
356A90Very high83.1Confident9 Ų950.8 Ų50.87%0.07428%0.276CS..Hα-helixtrans-61.8-37173.500000111.7V294 I352 D353 V358 G360 N361V294-A356 HydrophobicContact CG1-CB 4.14Å; V294-A356 HydrophobicContact CG2-CB 3.97Å; I352-A356 VanDerWaalsContact O-CB 3.26Å; I352-A356 WeakPolarHBondContact O-CB 3.39Å; I352-A356 PolarHBondContact O-N 2.98Å; D353-A356 PolarHBondContact O-N 2.81Å; A356-V358 VanDerWaalsContact C-N 3.31Å; A356-V358 PolarHBondContact O-N 3.13Å; A356-G360 CarbonylContact O-C 2.95Å; A356-G360 WeakPolarHBondContact O-CA 3.46Å; A356-G360 PolarHBondContact O-N 3Å; A356-N361 HydrophobicContact CB-CB 4.49Å
357N89Confident81.8Confident129 Ų12956.6 Ų56.669%0.6930%0.303SS*.Hα-helixtrans-65.5-34.9173.5-73.4-35.3000112.5D353 A354 V355D353-N357 VanDerWaalsContact O-CG 3.3Å; D353-N357 PolarHBondContact O-N 3.43Å; D353-N357 PolarHBondContact O-ND2 3.38Å; D353-N357 VanDerWaalsContact O-ND2 3.16Å; A354-N357 PolarHBondContact O-N 3.29Å; V355-N357 VanDerWaalsContact C-N 3.3Å; V355-N357 PolarHBondContact O-N 3.47Å
358V90.7Very high80.7Confident44 Ų4462.9 Ų62.927%0.26733%0.332SS..Hα-helixtrans-71.4-47.7175.7176.80000111.4N298 V301 F311 A354 V355 A356 G360N298-V358 WeakPolarHBondContact CB-O 3.3Å; N298-V358 PolarHBondContact ND2-O 2.96Å; V301-V358 HydrophobicContact CG1-CG1 3.88Å; V301-V358 WeakPolarHBondContact CG1-O 3.35Å; F311-V358 HydrophobicContact CE1-CB 4.19Å; F311-V358 HydrophobicContact CE1-CG1 3.85Å; F311-V358 HydrophobicContact CZ-CG1 4.18Å; A354-V358 PolarHBondContact O-N 2.88Å; V355-V358 PolarHBondContact O-N 2.71Å; V355-V358 VanDerWaalsContact O-N 3.1Å; A356-V358 VanDerWaalsContact C-N 3.31Å; A356-V358 PolarHBondContact O-N 3.13Å; V358-G360 PolarHBondContact O-N 3.21Å
359L88.6Confident79.9Confident0 Ų059.8 Ų59.80%033%0.326CS..Hα-helixtrans-69.6-19.3177.6-66.6170000112.9V294 V296 T297 N298 V301 F311 L337 L343 L345 V355V294-L359 HydrophobicContact CB-CD1 4.47Å; V294-L359 HydrophobicContact CG1-CB 4.09Å; V294-L359 HydrophobicContact CG1-CD1 3.91Å; V296-L359 HydrophobicContact CG2-CD2 4.34Å; T297-L359 PolarHBondContact N-O 2.85Å; N298-L359 VanDerWaalsContact CB-C 3.43Å; N298-L359 VanDerWaalsContact CB-O 3.27Å; N298-L359 WeakPolarHBondContact CB-O 3.27Å; N298-L359 PolarHBondContact N-O 3.19Å; V301-L359 HydrophobicContact CG2-CD2 4.32Å; F311-L359 HydrophobicContact CE2-CD2 3.74Å; F311-L359 HydrophobicContact CE2-CG 4.29Å; F311-L359 HydrophobicContact CZ-CD2 3.59Å; F311-L359 HydrophobicContact CZ-CG 3.91Å; L337-L359 HydrophobicContact CD1-CD2 3.66Å; L343-L359 HydrophobicContact CD1-CD1 3.8Å; L343-L359 HydrophobicContact CD1-CD2 3.86Å; L343-L359 HydrophobicContact CD1-CG 4.47Å; L345-L359 HydrophobicContact CD1-CD1 4.06Å; L345-L359 HydrophobicContact CD2-CD1 4.3Å; V355-L359 HydrophobicContact CG1-CD1 3.62Å; V355-L359 HydrophobicContact CG1-CG 4.1Å; V355-L359 WeakPolarHBondContact O-CB 3.4Å; V355-L359 WeakPolarHBondContact O-CG 3.48Å; V355-L359 PolarHBondContact O-N 3.4Å
360G81.7Confident79.5Confident12 Ų1261 Ų6112%0.12433%0.327CS..  trans71.6169.8-156.300000110.9V294 T297 A356 V358V294-G360 VanDerWaalsContact CG1-O 3.26Å; V294-G360 WeakPolarHBondContact CG1-O 2.96Å; T297-G360 WeakPolarHBondContact OG1-CA 3.29Å; A356-G360 CarbonylContact O-C 2.95Å; A356-G360 WeakPolarHBondContact O-CA 3.46Å; A356-G360 PolarHBondContact O-N 3Å; V358-G360 PolarHBondContact O-N 3.21Å
361N79.4Confident79.3Confident67 Ų6761.7 Ų61.736%0.35832%0.322SS..  trans-157.635.6166.2-163.515.9000108.6V294 V295 T297 A356 Q363V294-N361 HydrophobicContact CG1-CB 4.11Å; V295-N361 PolarHBondContact N-OD1 2.91Å; T297-N361 PolarHBondContact OG1-N 3.25Å; A356-N361 HydrophobicContact CB-CB 4.49Å; N361-Q363 PolarHBondContact O-N 2.95Å
362A64.2Low79.3Confident38 Ų3866.6 Ų66.631%0.31435%0.346SS..  trans-8275.5-174.200000108.5T297 Q364 K365T297-A362 PolarHBondContact OG1-N 3.49Å; T297-A362 VanDerWaalsContact OG1-N 3.12Å; A362-Q364 PolarHBondContact O-N 3.06Å; A362-K365 HydrophobicContact CB-CB 4.16Å; A362-K365 HydrophobicContact CB-CD 4.15Å; A362-K365 HydrophobicContact CB-CG 3.92Å; A362-K365 WeakPolarHBondContact O-CB 3.15Å; A362-K365 PolarHBondContact O-N 2.86Å
363Q61.3Low79.2Confident106 Ų10666.7 Ų66.750%0.49535%0.347SS..THydrogen-bonded Turntrans-53.4-29.7176.1-67.7-174.23.800111.7V295 N361 K365 L366 Q367V295-Q363 HydrophobicContact CG2-CG 4.39Å; N361-Q363 PolarHBondContact O-N 2.95Å; Q363-K365 VanDerWaalsContact C-N 3.35Å; Q363-K365 PolarHBondContact O-N 3.23Å; Q363-L366 WeakPolarHBondContact O-CB 3.42Å; Q363-L366 PolarHBondContact O-N 3.45Å; Q363-L366 VanDerWaalsContact O-N 3.12Å; Q363-Q367 WeakPolarHBondContact O-CG 3.2Å; Q363-Q367 PolarHBondContact O-N 3.35Å
364Q56Low79.2Confident140 Ų14063 Ų6365%0.65433%0.327SS*.THydrogen-bonded Turntrans-60.6-35.6171.4-85.6-178.1-13.300114.1A362 L366 Q367 Q368A362-Q364 PolarHBondContact O-N 3.06Å; Q364-L366 PolarHBondContact O-N 3.01Å; Q364-Q367 CarbonylContact O-C 3.53Å; Q364-Q367 WeakPolarHBondContact O-CA 3.46Å; Q364-Q367 WeakPolarHBondContact O-CB 3.47Å; Q364-Q367 PolarHBondContact O-N 3.22Å; Q364-Q368 WeakPolarHBondContact O-CG 3.26Å; Q364-Q368 PolarHBondContact O-N 3.02Å
365K57.1Low79.2Confident114 Ų11467.4 Ų67.450%0.49634%0.341SS..THydrogen-bonded Turntrans-66-29.6174.8-75.6-169.2174.6-171.40112A362 Q363 Q367A362-K365 HydrophobicContact CB-CB 4.16Å; A362-K365 HydrophobicContact CB-CD 4.15Å; A362-K365 HydrophobicContact CB-CG 3.92Å; A362-K365 WeakPolarHBondContact O-CB 3.15Å; A362-K365 PolarHBondContact O-N 2.86Å; Q363-K365 VanDerWaalsContact C-N 3.35Å; Q363-K365 PolarHBondContact O-N 3.23Å; K365-Q367 PolarHBondContact O-N 3.07Å
366L62.6Low79.3Confident30 Ų3070.3 Ų70.316%0.15736%0.356CS..THydrogen-bonded Turntrans-75.6-8.3171.6-63.1162.4000112.9V295 T297 F339 Q363 Q364 F425 P427V295-L366 HydrophobicContact CB-CD1 3.91Å; V295-L366 HydrophobicContact CG1-CD1 3.35Å; V295-L366 HydrophobicContact CG2-CD1 4.39Å; T297-L366 HydrophobicContact CG2-CD1 3.86Å; T297-L366 HydrophobicContact CG2-CD2 4.43Å; T297-L366 HydrophobicContact CG2-CG 3.92Å; F339-L366 HydrophobicContact CD1-CD2 4.02Å; F339-L366 HydrophobicContact CE1-CD2 3.31Å; F339-L366 HydrophobicContact CE1-CG 4.47Å; F339-L366 HydrophobicContact CE2-CD2 4.47Å; F339-L366 HydrophobicContact CZ-CD2 3.57Å; F339-L366 HydrophobicContact CZ-CG 4.33Å; Q363-L366 WeakPolarHBondContact O-CB 3.42Å; Q363-L366 PolarHBondContact O-N 3.45Å; Q363-L366 VanDerWaalsContact O-N 3.12Å; Q364-L366 PolarHBondContact O-N 3.01Å; L366-F425 HydrophobicContact CD2-CE1 4.16Å; L366-P427 WeakPolarHBondContact O-CB 3.3Å; L366-P427 WeakPolarHBondContact O-CG 3.49Å
367Q67.8Low79.5Confident124 Ų12469.9 Ų69.958%0.57935%0.352SS*.THydrogen-bonded Turntrans-103.6-18.4177.2-65.9171.7-900112.4Q363 Q364 K365 P427Q363-Q367 WeakPolarHBondContact O-CG 3.2Å; Q363-Q367 PolarHBondContact O-N 3.35Å; Q364-Q367 CarbonylContact O-C 3.53Å; Q364-Q367 WeakPolarHBondContact O-CA 3.46Å; Q364-Q367 WeakPolarHBondContact O-CB 3.47Å; Q364-Q367 PolarHBondContact O-N 3.22Å; K365-Q367 PolarHBondContact O-N 3.07Å; Q367-P427 VanDerWaalsContact C-CG 3.46Å
368Q70.2Confident79.8Confident132 Ų13264.6 Ų64.662%0.61732%0.324SS*.SBendtrans-89.7126.8179.2-71.9-179.4-0.800111.5Q364Q364-Q368 WeakPolarHBondContact O-CG 3.26Å; Q364-Q368 PolarHBondContact O-N 3.02Å
369V75.5Confident80.1Confident48 Ų4864 Ų6429%0.29133%0.327SS..  trans-78.6128.4171.3-177.40000109.1M371 V374 M426 P427 A430V369-M371 HydrophobicContact CB-SD 4.34Å; V369-M371 HydrophobicContact CG1-SD 3.71Å; V369-M371 PolarHBondContact O-N 3.49Å; V369-V374 HydrophobicContact CG1-CG2 4.09Å; V369-M426 HydrophobicContact CG1-CE 4.2Å; V369-M426 HydrophobicContact CG1-CG 4.43Å; V369-M426 HydrophobicContact CG2-CG 4.21Å; V369-P427 HydrophobicContact CG2-CG 4.27Å; V369-A430 HydrophobicContact CG2-CB 3.01Å
370Q81.7Confident80.4Confident71 Ų7167.5 Ų67.533%0.33235%0.345SS..  trans-83.9104.1164.1-62.1-176.725.100108.5L372 P373 K421Q370-L372 PolarHBondContact O-N 2.91Å; Q370-P373 HydrophobicContact CB-CG 3.8Å; Q370-P373 WeakPolarHBondContact O-CD 3.24Å; Q370-K421 PolarHBondContact OE1-O 3.27Å
371M88.3Confident81.1Confident103 Ų10366.9 Ų66.951%0.50734%0.339SS..Hα-helixtrans-65.8-28.4-178.6-63.3-60.9-86.800112.4V369 V374 F375V369-M371 HydrophobicContact CB-SD 4.34Å; V369-M371 HydrophobicContact CG1-SD 3.71Å; V369-M371 PolarHBondContact O-N 3.49Å; M371-V374 WeakPolarHBondContact O-CB 3.19Å; M371-V374 PolarHBondContact O-N 3.09Å; M371-F375 HydrophobicContact CB-CD2 4.34Å; M371-F375 HydrophobicContact CB-CE2 4.33Å; M371-F375 HydrophobicContact CE-CE2 4.06Å; M371-F375 VanDerWaalsContact O-CD2 3.26Å; M371-F375 WeakPolarHBondContact O-CD2 3.37Å; M371-F375 PolarHBondContact O-N 3.46Å
372L91.1Very high81.8Confident112 Ų11265.7 Ų65.759%0.58633%0.334SS*.Hα-helixtrans-61.6-54-178.7179.268.2000112.5Q370 V374 F375 I376 L422Q370-L372 PolarHBondContact O-N 2.91Å; L372-V374 VanDerWaalsContact C-N 3.26Å; L372-V374 PolarHBondContact O-N 3.36Å; L372-F375 PolarHBondContact O-N 2.92Å; L372-I376 HydrophobicContact CD1-CD1 3.87Å; L372-I376 HydrophobicContact CD1-CG1 4.26Å; L372-I376 HydrophobicContact CG-CD1 3.83Å; L372-I376 VanDerWaalsContact O-CG1 3.31Å; L372-I376 WeakPolarHBondContact O-CG1 3.26Å; L372-I376 PolarHBondContact O-N 3.27Å; L372-L422 HydrophobicContact CD2-CD2 3.62Å; L372-L422 HydrophobicContact CG-CD2 3.97Å
373P90.1Very high83.2Confident2 Ų269.5 Ų69.51%0.01335%0.349CS..Hα-helixtrans-51.7-40.1169-28.732.4000114Y72 Q370 I376 G377 L422 Y423 W424Y72-P373 PolarHBondContact OH-O 3.17Å; Q370-P373 HydrophobicContact CB-CG 3.8Å; Q370-P373 WeakPolarHBondContact O-CD 3.24Å; P373-I376 PolarHBondContact O-N 3.34Å; P373-G377 PolarHBondContact O-N 3Å; P373-L422 HydrophobicContact CG-CB 4.14Å; P373-L422 HydrophobicContact CG-CD2 3.95Å; P373-Y423 WeakPolarHBondContact CB-O 3.48Å; P373-Y423 WeakPolarHBondContact CG-O 3.18Å; P373-W424 HydrophobicContact CB-CD2 4.25Å; P373-W424 HydrophobicContact CB-CE3 3.67Å; P373-W424 HydrophobicContact CB-CH2 4.46Å; P373-W424 HydrophobicContact CB-CZ3 3.83Å; P373-W424 WeakPolarHBondContact O-CZ3 3.46Å
374V91.5Very high84.8Confident10 Ų1066.9 Ų66.96%0.06134%0.338CS..Hα-helixtrans-61.4-52-179.7178.30000111.1Y72 V369 M371 L372 G377 I378 M426 L434Y72-V374 HydrophobicContact CD1-CG1 4.42Å; Y72-V374 HydrophobicContact CE1-CB 4.4Å; Y72-V374 HydrophobicContact CE1-CG1 3.95Å; V369-V374 HydrophobicContact CG1-CG2 4.09Å; M371-V374 WeakPolarHBondContact O-CB 3.19Å; M371-V374 PolarHBondContact O-N 3.09Å; L372-V374 VanDerWaalsContact C-N 3.26Å; L372-V374 PolarHBondContact O-N 3.36Å; V374-G377 PolarHBondContact O-N 2.88Å; V374-I378 HydrophobicContact CG1-CD1 3.88Å; V374-I378 WeakPolarHBondContact O-CB 3.27Å; V374-I378 WeakPolarHBondContact O-CG1 3.37Å; V374-I378 PolarHBondContact O-N 2.97Å; V374-M426 HydrophobicContact CB-CE 4.44Å; V374-M426 HydrophobicContact CG1-CE 4.29Å; V374-M426 HydrophobicContact CG2-CE 3.29Å; V374-L434 HydrophobicContact CG1-CD2 4.24Å
375F93.9Very high86.3Confident124 Ų12460.2 Ų60.254%0.54431%0.306SS..Hα-helixtrans-68.3-37-179.6-76.4-70.6000113M371 L372 G379M371-F375 HydrophobicContact CB-CD2 4.34Å; M371-F375 HydrophobicContact CB-CE2 4.33Å; M371-F375 HydrophobicContact CE-CE2 4.06Å; M371-F375 VanDerWaalsContact O-CD2 3.26Å; M371-F375 WeakPolarHBondContact O-CD2 3.37Å; M371-F375 PolarHBondContact O-N 3.46Å; L372-F375 PolarHBondContact O-N 2.92Å; F375-G379 PolarHBondContact O-N 2.82Å
376I94.9Very high87.8Confident61 Ų6157.6 Ų57.631%0.31330%0.302SS..Hα-helixtrans-63.1-46.5173.7-66169.1000109.9L372 P373 I378 G379 L380 L422 W424L372-I376 HydrophobicContact CD1-CD1 3.87Å; L372-I376 HydrophobicContact CD1-CG1 4.26Å; L372-I376 HydrophobicContact CG-CD1 3.83Å; L372-I376 VanDerWaalsContact O-CG1 3.31Å; L372-I376 WeakPolarHBondContact O-CG1 3.26Å; L372-I376 PolarHBondContact O-N 3.27Å; P373-I376 PolarHBondContact O-N 3.34Å; I376-I378 PolarHBondContact O-N 2.98Å; I376-G379 PolarHBondContact O-N 3.48Å; I376-L380 HydrophobicContact CG2-CD1 3.79Å; I376-L380 HydrophobicContact CG2-CG 4.17Å; I376-L380 WeakPolarHBondContact O-CB 3.48Å; I376-L380 VanDerWaalsContact O-CG 3.29Å; I376-L380 WeakPolarHBondContact O-CG 3.23Å; I376-L380 PolarHBondContact O-N 2.84Å; I376-L422 HydrophobicContact CD1-CD1 4.04Å; I376-W424 HydrophobicContact CB-CH2 4.03Å; I376-W424 HydrophobicContact CB-CZ3 4.26Å; I376-W424 HydrophobicContact CG2-CH2 3.72Å; I376-W424 HydrophobicContact CG2-CZ3 4.28Å
377G94.7Very high89Confident0 Ų060.6 Ų60.60%032%0.318CS..Hα-helixtrans-64.3-41.6-178.800000112.6Y72 P373 V374 G381Y72-G377 VanDerWaalsContact CE2-C 3.41Å; P373-G377 PolarHBondContact O-N 3Å; V374-G377 PolarHBondContact O-N 2.88Å; G377-G381 PolarHBondContact O-N 3.36Å
378I94.5Very high89.8Confident18 Ų1857.6 Ų57.69%0.09231%0.309CS..Hα-helixtrans-62.9-48.3173-71.5170000110.5I68 L69 Y72 V374 I376 L380 G381 V382I68-I378 HydrophobicContact CG2-CB 4.45Å; I68-I378 HydrophobicContact CG2-CD1 4.43Å; I68-I378 HydrophobicContact CG2-CG1 4.19Å; I68-I378 HydrophobicContact CG2-CG2 3.54Å; L69-I378 HydrophobicContact CD2-CD1 3.89Å; Y72-I378 HydrophobicContact CD1-CD1 4.26Å; Y72-I378 HydrophobicContact CD1-CG1 3.92Å; Y72-I378 HydrophobicContact CD2-CG1 3.76Å; Y72-I378 HydrophobicContact CE1-CG1 4.32Å; Y72-I378 HydrophobicContact CE2-CG1 4.19Å; Y72-I378 HydrophobicContact CG-CD1 4.36Å; Y72-I378 HydrophobicContact CG-CG1 3.63Å; V374-I378 HydrophobicContact CG1-CD1 3.88Å; V374-I378 WeakPolarHBondContact O-CB 3.27Å; V374-I378 WeakPolarHBondContact O-CG1 3.37Å; V374-I378 PolarHBondContact O-N 2.97Å; I376-I378 PolarHBondContact O-N 2.98Å; I378-L380 PolarHBondContact O-N 3.46Å; I378-G381 CarbonylContact O-C 3.59Å; I378-G381 WeakPolarHBondContact O-CA 3.34Å; I378-G381 PolarHBondContact O-N 2.99Å; I378-G381 VanDerWaalsContact O-N 3.11Å; I378-V382 HydrophobicContact CG2-CG2 4.31Å; I378-V382 WeakPolarHBondContact O-CG2 3.37Å; I378-V382 PolarHBondContact O-N 2.87Å
379G96Very high90.4Very high32 Ų3255 Ų5533%0.3330%0.302SS..Hα-helixtrans-58.6-48.6179.300000112.5F375 I376 G381 V382 L383F375-G379 PolarHBondContact O-N 2.82Å; I376-G379 PolarHBondContact O-N 3.48Å; G379-G381 VanDerWaalsContact C-N 3.28Å; G379-G381 PolarHBondContact O-N 2.88Å; G379-V382 PolarHBondContact O-N 3.01Å; G379-L383 WeakPolarHBondContact O-CB 3.41Å; G379-L383 VanDerWaalsContact O-CG 3.31Å; G379-L383 WeakPolarHBondContact O-CG 3.48Å; G379-L383 PolarHBondContact O-N 3.12Å
380L96.6Very high90.6Very high73 Ų7360.7 Ų60.738%0.38232%0.323SS..Hα-helixtrans-60.9-38.7174-69.6176.1000111.9I376 I378 L383 L384 M409I376-L380 HydrophobicContact CG2-CD1 3.79Å; I376-L380 HydrophobicContact CG2-CG 4.17Å; I376-L380 WeakPolarHBondContact O-CB 3.48Å; I376-L380 VanDerWaalsContact O-CG 3.29Å; I376-L380 WeakPolarHBondContact O-CG 3.23Å; I376-L380 PolarHBondContact O-N 2.84Å; I378-L380 PolarHBondContact O-N 3.46Å; L380-L383 PolarHBondContact O-N 3.44Å; L380-L384 WeakPolarHBondContact O-CB 3.43Å; L380-L384 PolarHBondContact O-N 3.48Å; L380-M409 HydrophobicContact CB-CE 4.49Å; L380-M409 HydrophobicContact CB-CG 4.3Å
381G95.2Very high90.1Very high0 Ų060 Ų600%032%0.323CS..Hα-helixtrans-62.9-46.4176.200000113.3G377 I378 G379 L384 G385 G405 P406G377-G381 PolarHBondContact O-N 3.36Å; I378-G381 CarbonylContact O-C 3.59Å; I378-G381 WeakPolarHBondContact O-CA 3.34Å; I378-G381 PolarHBondContact O-N 2.99Å; I378-G381 VanDerWaalsContact O-N 3.11Å; G379-G381 VanDerWaalsContact C-N 3.28Å; G379-G381 PolarHBondContact O-N 2.88Å; G381-L384 PolarHBondContact O-N 2.95Å; G381-G385 PolarHBondContact O-N 3.42Å; G381-G405 CarbonylContact O-C 3.57Å; G381-G405 VanDerWaalsContact O-CA 3.23Å; G381-G405 WeakPolarHBondContact O-CA 3.34Å; G381-P406 WeakPolarHBondContact O-CD 3.21Å
382V93.7Very high89.4Confident41 Ų4161.1 Ų61.125%0.24834%0.338CS..Hα-helixtrans-65.1-41.9176.7171.40000110.6I68 I378 G379 G385 S386 L402 P406I68-V382 HydrophobicContact CD1-CG2 4.11Å; I378-V382 HydrophobicContact CG2-CG2 4.31Å; I378-V382 WeakPolarHBondContact O-CG2 3.37Å; I378-V382 PolarHBondContact O-N 2.87Å; G379-V382 PolarHBondContact O-N 3.01Å; V382-G385 PolarHBondContact O-N 3.26Å; V382-S386 WeakPolarHBondContact O-CB 3.3Å; V382-S386 PolarHBondContact O-N 3.03Å; V382-S386 PolarHBondContact O-OG 3.48Å; V382-L402 HydrophobicContact CB-CD2 4.34Å; V382-L402 HydrophobicContact CG1-CD2 3.77Å; V382-L402 HydrophobicContact CG2-CD2 4Å; V382-P406 HydrophobicContact CG2-CG 4.24Å
383L95Very high88.5Confident119 Ų11959.3 Ų59.362%0.62335%0.347SS*.Hα-helixtrans-59.7-51.5174.8-73172.7000111.1G379 L380 G385 S386 I387G379-L383 WeakPolarHBondContact O-CB 3.41Å; G379-L383 VanDerWaalsContact O-CG 3.31Å; G379-L383 WeakPolarHBondContact O-CG 3.48Å; G379-L383 PolarHBondContact O-N 3.12Å; L380-L383 PolarHBondContact O-N 3.44Å; L383-G385 VanDerWaalsContact C-N 3.28Å; L383-G385 PolarHBondContact O-N 3.35Å; L383-S386 PolarHBondContact O-N 2.78Å; L383-S386 VanDerWaalsContact O-N 3.13Å; L383-I387 WeakPolarHBondContact O-CG1 3.21Å; L383-I387 PolarHBondContact O-N 2.87Å
384L93.6Very high87.4Confident50 Ų5062.5 Ų62.526%0.26236%0.361SS..Hα-helixtrans-57.4-43.7175.6-17969.6000111.4L380 G381 S386 I387 L400 I408 M409L380-L384 WeakPolarHBondContact O-CB 3.43Å; L380-L384 PolarHBondContact O-N 3.48Å; G381-L384 PolarHBondContact O-N 2.95Å; L384-S386 PolarHBondContact O-N 2.83Å; L384-I387 HydrophobicContact CD1-CD1 4.27Å; L384-I387 PolarHBondContact O-N 3.47Å; L384-L400 HydrophobicContact CD2-CD1 4.49Å; L384-L400 HydrophobicContact CG-CD1 4.23Å; L384-I408 HydrophobicContact CD2-CB 4.08Å; L384-I408 HydrophobicContact CD2-CG2 3.78Å; L384-M409 HydrophobicContact CB-CG 4.04Å; L384-M409 HydrophobicContact CD2-CG 3.64Å; L384-M409 HydrophobicContact CD2-SD 3.76Å; L384-M409 HydrophobicContact CG-CG 4.47Å
385G88.8Confident86.1Confident0 Ų066.5 Ų66.50%039%0.387CS..Hα-helixtrans-59.7-31.1178.300000113.9G381 V382 L383 L400 G401G381-G385 PolarHBondContact O-N 3.42Å; V382-G385 PolarHBondContact O-N 3.26Å; L383-G385 VanDerWaalsContact C-N 3.28Å; L383-G385 PolarHBondContact O-N 3.35Å; G385-L400 PolarHBondContact O-N 2.89Å; G385-G401 VanDerWaalsContact CA-O 3.26Å; G385-G401 WeakPolarHBondContact CA-O 3.36Å; G385-G401 PolarHBondContact O-N 2.78Å
386S87.8Confident84.8Confident59 Ų5962 Ų6241%0.41337%0.373SS..Hα-helixtrans-87.6-8.8-174.9-57.30000113.6V382 L383 L384 P388V382-S386 WeakPolarHBondContact O-CB 3.3Å; V382-S386 PolarHBondContact O-N 3.03Å; V382-S386 PolarHBondContact O-OG 3.48Å; L383-S386 PolarHBondContact O-N 2.78Å; L383-S386 VanDerWaalsContact O-N 3.13Å; L384-S386 PolarHBondContact O-N 2.83Å; S386-P388 VanDerWaalsContact O-CD 3.28Å; S386-P388 WeakPolarHBondContact O-CD 3.39Å
387I88.8Confident83.8Confident93 Ų9360.5 Ų60.548%0.47737%0.369SS..  trans-69118.1179.8-58.4-179.4000109.2L383 L384 V389L383-I387 WeakPolarHBondContact O-CG1 3.21Å; L383-I387 PolarHBondContact O-N 2.87Å; L384-I387 HydrophobicContact CD1-CD1 4.27Å; L384-I387 PolarHBondContact O-N 3.47Å; I387-V389 PolarHBondContact O-N 2.94Å
388P84.8Confident82.6Confident61 Ų6162.2 Ų62.240%0.39638%0.378SS..  trans-72.7123.917528.5-30.8000110.3S386 F390 A397S386-P388 VanDerWaalsContact O-CD 3.28Å; S386-P388 WeakPolarHBondContact O-CD 3.39Å; P388-F390 HydrophobicContact CB-CE2 4.2Å; P388-F390 HydrophobicContact CG-CE2 4.35Å; P388-A397 HydrophobicContact CB-CB 3.59Å
389V81.3Confident81.9Confident77 Ų7765.2 Ų65.247%0.46739%0.391SS..BIsolated β-bridgetrans-104.1110.1173.3-177.30000108.4I387 V391 L398I387-V389 PolarHBondContact O-N 2.94Å; V389-V391 HydrophobicContact CG1-CG2 4.06Å; V389-V391 PolarHBondContact O-N 3.04Å; V389-L398 WeakPolarHBondContact CB-O 3.36Å; V389-L398 PolarHBondContact N-O 3.14Å; V389-L398 PolarHBondContact O-N 3.38Å
390F79.9Confident81Confident168 Ų16866 Ų6674%0.73739%0.387SS*.  trans-80.7106.3175-64.3-88000109.1P388 A397P388-F390 HydrophobicContact CB-CE2 4.2Å; P388-F390 HydrophobicContact CG-CE2 4.35Å; F390-A397 HydrophobicContact CD1-CB 3.79Å; F390-A397 HydrophobicContact CD2-CB 4.47Å; F390-A397 HydrophobicContact CE1-CB 3.55Å; F390-A397 HydrophobicContact CE2-CB 4.25Å; F390-A397 HydrophobicContact CG-CB 4.26Å; F390-A397 HydrophobicContact CZ-CB 3.8Å
391V72.4Confident80.4Confident56 Ų5662.7 Ų62.734%0.33937%0.37SS..  trans-95.5124.6173.9-1790000108.3V389 G393 F394 L398V389-V391 HydrophobicContact CG1-CG2 4.06Å; V389-V391 PolarHBondContact O-N 3.04Å; V391-G393 PolarHBondContact O-N 3.06Å; V391-F394 HydrophobicContact CB-CD2 3.76Å; V391-F394 HydrophobicContact CB-CE2 4.4Å; V391-F394 HydrophobicContact CG1-CD2 3.67Å; V391-F394 HydrophobicContact CG1-CE2 3.89Å; V391-F394 PolarHBondContact O-N 3.33Å; V391-L398 HydrophobicContact CB-CD1 4.33Å; V391-L398 HydrophobicContact CG2-CD1 3.86Å
392P73.2Confident79.9Confident127 Ų12764.5 Ų64.583%0.82538%0.38SS*.THydrogen-bonded Turntrans-54.1127.3176.9-24.232.9000111.3
393G72.3Confident79.3Confident74 Ų7462.5 Ų62.576%0.76337%0.368SS*.THydrogen-bonded Turntrans101-8-179.300000115.6V391V391-G393 PolarHBondContact O-N 3.06Å
394F65.5Low78.7Confident69 Ų6957 Ų5730%0.30334%0.34SS..  trans-102.4142.1176.9-71.6-72000113.2V391 A396 V547V391-F394 HydrophobicContact CB-CD2 3.76Å; V391-F394 HydrophobicContact CB-CE2 4.4Å; V391-F394 HydrophobicContact CG1-CD2 3.67Å; V391-F394 HydrophobicContact CG1-CE2 3.89Å; V391-F394 PolarHBondContact O-N 3.33Å; F394-A396 VanDerWaalsContact C-N 3.29Å; F394-A396 PolarHBondContact O-N 3.44Å; F394-V547 HydrophobicContact CD1-CG1 3.26Å; F394-V547 HydrophobicContact CD2-CG1 4.24Å; F394-V547 HydrophobicContact CE1-CB 4.21Å; F394-V547 HydrophobicContact CE1-CG1 2.99Å; F394-V547 WeakPolarHBondContact CE1-O 3.48Å; F394-V547 HydrophobicContact CE2-CG1 3.97Å; F394-V547 HydrophobicContact CG-CG1 3.9Å; F394-V547 HydrophobicContact CZ-CG1 3.35Å
395P65.8Low78.6Confident94 Ų9454.7 Ų54.761%0.6133%0.328SS*.SBendtrans-74.4-18.6-176.928.8-34000113.5
396A66.2Low78.7Confident30 Ų3054.7 Ų54.725%0.24833%0.328CS..SBendtrans-129.9148.7-17900000111.1L146 F394 L398L146-A396 HydrophobicContact CD2-CB 4.09Å; F394-A396 VanDerWaalsContact C-N 3.29Å; F394-A396 PolarHBondContact O-N 3.44Å; A396-L398 PolarHBondContact O-N 3.19Å
397A72.9Confident78.8Confident29 Ų2952 Ų5224%0.2431%0.309CS..  trans-67.1123.8172.100000109.7P388 F390P388-A397 HydrophobicContact CB-CB 3.59Å; F390-A397 HydrophobicContact CD1-CB 3.79Å; F390-A397 HydrophobicContact CD2-CB 4.47Å; F390-A397 HydrophobicContact CE1-CB 3.55Å; F390-A397 HydrophobicContact CE2-CB 4.25Å; F390-A397 HydrophobicContact CG-CB 4.26Å; F390-A397 HydrophobicContact CZ-CB 3.8Å
398L69.8Low78.8Confident36 Ų3649.4 Ų49.419%0.18830%0.296CS..BIsolated β-bridgetrans-76.5129.5-179.4-60.7-179000109.7I142 V389 V391 A396 V547I142-L398 HydrophobicContact CD1-CD2 4.22Å; V389-L398 WeakPolarHBondContact CB-O 3.36Å; V389-L398 PolarHBondContact N-O 3.14Å; V389-L398 PolarHBondContact O-N 3.38Å; V391-L398 HydrophobicContact CB-CD1 4.33Å; V391-L398 HydrophobicContact CG2-CD1 3.86Å; A396-L398 PolarHBondContact O-N 3.19Å; L398-V547 HydrophobicContact CD1-CG1 4.01Å; L398-V547 HydrophobicContact CD1-CG2 4.43Å; L398-V547 HydrophobicContact CD2-CB 4.34Å; L398-V547 HydrophobicContact CD2-CG1 3.96Å; L398-V547 HydrophobicContact CD2-CG2 3.35Å
399K79.4Confident79.2Confident81 Ų8148 Ų4835%0.35228%0.284SS..  trans-110.8142.6171-69.5177.1-175.8170.50108.6G401K399-G401 PolarHBondContact O-N 3.17Å
400L78.8Confident79.7Confident49 Ų4944.3 Ų44.326%0.25726%0.262SS..  trans-65.3-28.1171.2-75.7167.7000111.3L384 G385 G404 I408 Q543L384-L400 HydrophobicContact CD2-CD1 4.49Å; L384-L400 HydrophobicContact CG-CD1 4.23Å; G385-L400 PolarHBondContact O-N 2.89Å; L400-G404 VanDerWaalsContact O-CA 3.3Å; L400-G404 WeakPolarHBondContact O-CA 3.08Å; L400-G404 PolarHBondContact O-N 3.11Å; L400-G404 VanDerWaalsContact O-N 3.08Å; L400-I408 HydrophobicContact CD1-CD1 3.77Å; L400-I408 HydrophobicContact CD2-CD1 3.75Å; L400-I408 HydrophobicContact CG-CD1 4.37Å; L400-Q543 PolarHBondContact O-NE2 3.32Å
401G83.5Confident80Confident3 Ų336.8 Ų36.83%0.03123%0.229CC..Hα-helixtrans78.6-176.2177.300000114.4G385 K399 A403 G405G385-G401 VanDerWaalsContact CA-O 3.26Å; G385-G401 WeakPolarHBondContact CA-O 3.36Å; G385-G401 PolarHBondContact O-N 2.78Å; K399-G401 PolarHBondContact O-N 3.17Å; G401-A403 VanDerWaalsContact C-N 3.26Å; G401-G405 PolarHBondContact O-N 3.4Å
402L85.3Confident80.9Confident38 Ų3837.3 Ų37.320%0.19923%0.23CC..Hα-helixtrans-73.2-17.9177.1-57.8-179.2000111.9E64 I68 V382 P406E64-L402 HydrophobicContact CB-CD1 3.99Å; E64-L402 HydrophobicContact CG-CD1 4.21Å; I68-L402 HydrophobicContact CD1-CB 4.12Å; I68-L402 HydrophobicContact CD1-CD1 4.26Å; I68-L402 HydrophobicContact CD1-CD2 4.2Å; I68-L402 HydrophobicContact CD1-CG 4.41Å; I68-L402 HydrophobicContact CG1-CB 3.91Å; V382-L402 HydrophobicContact CB-CD2 4.34Å; V382-L402 HydrophobicContact CG1-CD2 3.77Å; V382-L402 HydrophobicContact CG2-CD2 4Å; L402-P406 VanDerWaalsContact O-CD 3.24Å; L402-P406 WeakPolarHBondContact O-CD 3.28Å; L402-P406 WeakPolarHBondContact O-CG 3.43Å
403A81.1Confident81.7Confident0 Ų031.6 Ų31.60%019%0.192CC..Hα-helixtrans-81-58.5165.300000111.6L67 V71 A138 G401 L407L67-A403 HydrophobicContact CD2-CB 4.12Å; L67-A403 HydrophobicContact CG-CB 4.48Å; V71-A403 WeakPolarHBondContact CG1-O 3.35Å; A138-A403 HydrophobicContact CB-CB 3.75Å; G401-A403 VanDerWaalsContact C-N 3.26Å; A403-L407 PolarHBondContact O-N 3.01Å
404G82.5Confident82.2Confident4 Ų428.3 Ų28.34%0.04116%0.158CC..Hα-helixtrans-71.7-41.9-169.500000114.1L400 L407 I408L400-G404 VanDerWaalsContact O-CA 3.3Å; L400-G404 WeakPolarHBondContact O-CA 3.08Å; L400-G404 PolarHBondContact O-N 3.11Å; L400-G404 VanDerWaalsContact O-N 3.08Å; G404-L407 WeakPolarHBondContact O-CB 3.35Å; G404-L407 PolarHBondContact O-N 2.83Å; G404-I408 WeakPolarHBondContact O-CG1 3.3Å; G404-I408 PolarHBondContact O-N 3.27Å
405G89.6Confident82.9Confident0 Ų030.6 Ų30.60%017%0.165CC..Hα-helixtrans-61.8-55.9-178.100000113G381 G401 L407 I408 M409G381-G405 CarbonylContact O-C 3.57Å; G381-G405 VanDerWaalsContact O-CA 3.23Å; G381-G405 WeakPolarHBondContact O-CA 3.34Å; G401-G405 PolarHBondContact O-N 3.4Å; G405-L407 VanDerWaalsContact C-N 3.3Å; G405-L407 PolarHBondContact O-N 2.85Å; G405-I408 PolarHBondContact O-N 2.8Å; G405-M409 PolarHBondContact O-N 3.04Å
406P92.1Very high83.6Confident0 Ų030 Ų300%016%0.156CC..Hα-helixtrans-56.9-37.6174-30.540.4000114I68 G381 V382 L402 A410I68-P406 HydrophobicContact CG1-CG 4.43Å; I68-P406 HydrophobicContact CG2-CB 4.45Å; I68-P406 HydrophobicContact CG2-CG 4.28Å; G381-P406 WeakPolarHBondContact O-CD 3.21Å; V382-P406 HydrophobicContact CG2-CG 4.24Å; L402-P406 VanDerWaalsContact O-CD 3.24Å; L402-P406 WeakPolarHBondContact O-CD 3.28Å; L402-P406 WeakPolarHBondContact O-CG 3.43Å; P406-A410 WeakPolarHBondContact O-CB 3.39Å; P406-A410 PolarHBondContact O-N 3.44Å
407L89.5Confident83.9Confident3 Ų329.9 Ų29.92%0.01616%0.157CC..Hα-helixtrans-59.8-53.9174.4-176.666.2000111.7V71 I74 A403 G404 G405 A410 L411 F536 I539V71-L407 HydrophobicContact CG1-CB 3.49Å; V71-L407 VanDerWaalsContact CG1-CB 3.49Å; V71-L407 HydrophobicContact CG1-CD1 3.93Å; V71-L407 HydrophobicContact CG1-CG 4.2Å; I74-L407 HydrophobicContact CG2-CD1 3.86Å; A403-L407 PolarHBondContact O-N 3.01Å; G404-L407 WeakPolarHBondContact O-CB 3.35Å; G404-L407 PolarHBondContact O-N 2.83Å; G405-L407 VanDerWaalsContact C-N 3.3Å; G405-L407 PolarHBondContact O-N 2.85Å; L407-A410 PolarHBondContact O-N 3.49Å; L407-L411 HydrophobicContact CD1-CD1 4.43Å; L407-L411 HydrophobicContact CD1-CG 4.5Å; L407-L411 HydrophobicContact CG-CD1 4.04Å; L407-L411 HydrophobicContact CG-CG 4.48Å; L407-L411 WeakPolarHBondContact O-CG 3.5Å; L407-L411 PolarHBondContact O-N 2.87Å; L407-F536 HydrophobicContact CD2-CD2 4.11Å; L407-I539 HydrophobicContact CD1-CD1 4.4Å; L407-I539 HydrophobicContact CD2-CB 4.4Å; L407-I539 HydrophobicContact CD2-CD1 3.47Å; L407-I539 VanDerWaalsContact CD2-CD1 3.47Å; L407-I539 HydrophobicContact CD2-CG2 4.28Å
408I88.8Confident84.1Confident38 Ų3830.6 Ų30.620%0.19516%0.16CC..Hα-helixtrans-64.3-45.9-174-71167.6000110L384 L400 G404 G405 A410 L411 I412 F536L384-I408 HydrophobicContact CD2-CB 4.08Å; L384-I408 HydrophobicContact CD2-CG2 3.78Å; L400-I408 HydrophobicContact CD1-CD1 3.77Å; L400-I408 HydrophobicContact CD2-CD1 3.75Å; L400-I408 HydrophobicContact CG-CD1 4.37Å; G404-I408 WeakPolarHBondContact O-CG1 3.3Å; G404-I408 PolarHBondContact O-N 3.27Å; G405-I408 PolarHBondContact O-N 2.8Å; I408-A410 VanDerWaalsContact C-N 3.33Å; I408-A410 PolarHBondContact O-N 2.95Å; I408-L411 WeakPolarHBondContact O-CB 3.31Å; I408-L411 PolarHBondContact O-N 3.33Å; I408-I412 HydrophobicContact CG2-CD1 3.88Å; I408-I412 WeakPolarHBondContact O-CG1 3.02Å; I408-I412 PolarHBondContact O-N 2.85Å; I408-F536 HydrophobicContact CD1-CE2 4.31Å; I408-F536 HydrophobicContact CG1-CE2 4Å
409M93.8Very high84.5Confident31 Ų3133 Ų3315%0.15317%0.173CC..Hα-helixtrans-63.8-40.1176.6-79.8-44.6-5300112.2L380 L384 G405 L411 I412 L413L380-M409 HydrophobicContact CB-CE 4.49Å; L380-M409 HydrophobicContact CB-CG 4.3Å; L384-M409 HydrophobicContact CB-CG 4.04Å; L384-M409 HydrophobicContact CD2-CG 3.64Å; L384-M409 HydrophobicContact CD2-SD 3.76Å; L384-M409 HydrophobicContact CG-CG 4.47Å; G405-M409 PolarHBondContact O-N 3.04Å; M409-L411 PolarHBondContact O-N 3.02Å; M409-I412 PolarHBondContact O-N 2.9Å; M409-I412 HydrophobicContact SD-CD1 4.2Å; M409-L413 HydrophobicContact CE-CD1 4.11Å; M409-L413 HydrophobicContact CE-CD2 4.33Å; M409-L413 HydrophobicContact CE-CG 3.98Å; M409-L413 VanDerWaalsContact O-CB 3.31Å; M409-L413 WeakPolarHBondContact O-CB 3.48Å; M409-L413 WeakPolarHBondContact O-CG 3.01Å; M409-L413 PolarHBondContact O-N 3.27Å
410A92Very high84.4Confident0 Ų032.3 Ų32.30%019%0.188CC..Hα-helixtrans-64.6-38176.100000112.6Y72 G75 I76 P406 L407 I408 G414Y72-A410 HydrophobicContact CD2-CB 3.61Å; Y72-A410 HydrophobicContact CE2-CB 3.83Å; Y72-A410 HydrophobicContact CG-CB 4.23Å; Y72-A410 VanDerWaalsContact O-CB 3.29Å; Y72-A410 WeakPolarHBondContact O-CB 3.25Å; G75-A410 CarbonylContact C-O 3.22Å; G75-A410 CarbonylContact O-C 3.59Å; I76-A410 HydrophobicContact CD1-CB 4.2Å; I76-A410 HydrophobicContact CG1-CB 3.98Å; P406-A410 WeakPolarHBondContact O-CB 3.39Å; P406-A410 PolarHBondContact O-N 3.44Å; L407-A410 PolarHBondContact O-N 3.49Å; I408-A410 VanDerWaalsContact C-N 3.33Å; I408-A410 PolarHBondContact O-N 2.95Å; A410-G414 WeakPolarHBondContact O-CA 3.16Å; A410-G414 PolarHBondContact O-N 2.93Å
411L86.5Confident84.2Confident10 Ų1037.9 Ų37.95%0.05221%0.21CC..Hα-helixtrans-61.4-46.1173.5-76.8170.1000111.7V78 G79 F82 L407 I408 M409 R415 F536V78-L411 HydrophobicContact CB-CD2 4.29Å; V78-L411 HydrophobicContact CG2-CD2 3.52Å; G79-L411 WeakPolarHBondContact CA-O 3.33Å; F82-L411 HydrophobicContact CB-CD2 4.04Å; F82-L411 HydrophobicContact CD2-CD2 4.4Å; F82-L411 HydrophobicContact CG-CD2 4.29Å; L407-L411 HydrophobicContact CD1-CD1 4.43Å; L407-L411 HydrophobicContact CD1-CG 4.5Å; L407-L411 HydrophobicContact CG-CD1 4.04Å; L407-L411 HydrophobicContact CG-CG 4.48Å; L407-L411 WeakPolarHBondContact O-CG 3.5Å; L407-L411 PolarHBondContact O-N 2.87Å; I408-L411 WeakPolarHBondContact O-CB 3.31Å; I408-L411 PolarHBondContact O-N 3.33Å; M409-L411 PolarHBondContact O-N 3.02Å; L411-R415 VanDerWaalsContact O-CB 3.3Å; L411-R415 WeakPolarHBondContact O-CB 3.35Å; L411-R415 PolarHBondContact O-N 3.45Å; L411-F536 HydrophobicContact CD1-CD2 4.15Å
412I89.2Confident84.1Confident68 Ų6840 Ų4035%0.34922%0.22SC..Hα-helixtrans-64.5-52.2179-67166.8000110.3I408 M409 R415 I416I408-I412 HydrophobicContact CG2-CD1 3.88Å; I408-I412 WeakPolarHBondContact O-CG1 3.02Å; I408-I412 PolarHBondContact O-N 2.85Å; M409-I412 PolarHBondContact O-N 2.9Å; M409-I412 HydrophobicContact SD-CD1 4.2Å; I412-R415 WeakPolarHBondContact O-CB 3.44Å; I412-R415 PolarHBondContact O-N 2.82Å; I412-I416 HydrophobicContact CG2-CD1 3.84Å; I412-I416 VanDerWaalsContact O-CG1 3.32Å; I412-I416 WeakPolarHBondContact O-CG1 3.45Å; I412-I416 PolarHBondContact O-N 3.47Å
413L90.6Very high83.8Confident7 Ų738.7 Ų38.74%0.03721%0.213CC..Hα-helixtrans-64.7-44-178-67.2169.5000111.3I76 M409 R415 I416 G417 I419 W424I76-L413 HydrophobicContact CD1-CB 4.33Å; M409-L413 HydrophobicContact CE-CD1 4.11Å; M409-L413 HydrophobicContact CE-CD2 4.33Å; M409-L413 HydrophobicContact CE-CG 3.98Å; M409-L413 VanDerWaalsContact O-CB 3.31Å; M409-L413 WeakPolarHBondContact O-CB 3.48Å; M409-L413 WeakPolarHBondContact O-CG 3.01Å; M409-L413 PolarHBondContact O-N 3.27Å; L413-R415 VanDerWaalsContact C-N 3.27Å; L413-R415 PolarHBondContact O-N 3.34Å; L413-I416 PolarHBondContact O-N 3.47Å; L413-I416 VanDerWaalsContact O-N 3.14Å; L413-G417 PolarHBondContact O-N 3.41Å; L413-I419 HydrophobicContact CD2-CD1 4.38Å; L413-W424 HydrophobicContact CB-CB 4.06Å; L413-W424 HydrophobicContact CB-CD2 3.85Å; L413-W424 HydrophobicContact CB-CE3 3.93Å; L413-W424 HydrophobicContact CB-CG 3.87Å; L413-W424 HydrophobicContact CD1-CD2 4.37Å; L413-W424 HydrophobicContact CD1-CE3 3.78Å; L413-W424 HydrophobicContact CD1-CH2 4.29Å; L413-W424 HydrophobicContact CD1-CZ3 3.71Å; L413-W424 HydrophobicContact CD2-CD2 3.9Å; L413-W424 HydrophobicContact CD2-CE3 4.13Å; L413-W424 HydrophobicContact CD2-CG 4.44Å; L413-W424 HydrophobicContact CD2-CH2 4.14Å; L413-W424 HydrophobicContact CD2-CZ2 3.93Å; L413-W424 HydrophobicContact CD2-CZ3 4.21Å; L413-W424 HydrophobicContact CG-CD2 4.24Å; L413-W424 HydrophobicContact CG-CE3 4.16Å; L413-W424 HydrophobicContact CG-CZ3 4.4Å; L413-W424 WeakPolarHBondContact O-CB 3.34Å
414G83Confident83.9Confident5 Ų539.2 Ų39.25%0.05222%0.215CC..Hα-helixtrans-59.2-37.7174.300000112.3P80 A410 G417P80-G414 WeakPolarHBondContact CG-O 3.37Å; A410-G414 WeakPolarHBondContact O-CA 3.16Å; A410-G414 PolarHBondContact O-N 2.93Å; G414-G417 PolarHBondContact O-N 3.11Å
415R79.7Confident83.5Confident116 Ų11643.1 Ų43.144%0.43823%0.231SC..Hα-helixtrans-69-38.9174.2173.460.1-173.2931.3113F83 L411 I412 L413F83-R415 HydrophobicContact CD2-CB 3.75Å; F83-R415 HydrophobicContact CD2-CG 3.55Å; F83-R415 HydrophobicContact CE2-CB 3.78Å; F83-R415 HydrophobicContact CE2-CG 3.86Å; F83-R415 HydrophobicContact CG-CG 4.22Å; L411-R415 VanDerWaalsContact O-CB 3.3Å; L411-R415 WeakPolarHBondContact O-CB 3.35Å; L411-R415 PolarHBondContact O-N 3.45Å; I412-R415 WeakPolarHBondContact O-CB 3.44Å; I412-R415 PolarHBondContact O-N 2.82Å; L413-R415 VanDerWaalsContact C-N 3.27Å; L413-R415 PolarHBondContact O-N 3.34Å
416I81.5Confident83.2Confident83 Ų8343.7 Ų43.743%0.42623%0.234SC..Hα-helixtrans-63.9-36.3175.7-68165.1000109.7I412 L413 S418 I419I412-I416 HydrophobicContact CG2-CD1 3.84Å; I412-I416 VanDerWaalsContact O-CG1 3.32Å; I412-I416 WeakPolarHBondContact O-CG1 3.45Å; I412-I416 PolarHBondContact O-N 3.47Å; L413-I416 PolarHBondContact O-N 3.47Å; L413-I416 VanDerWaalsContact O-N 3.14Å; I416-S418 WeakPolarHBondContact CG2-O 3.41Å; I416-S418 PolarHBondContact O-N 2.96Å; I416-I419 HydrophobicContact CD1-CD1 4.46Å; I416-I419 HydrophobicContact CG2-CD1 4.21Å; I416-I419 HydrophobicContact CG2-CG1 3.65Å
417G73Confident82.5Confident27 Ų2743.8 Ų43.828%0.27823%0.234SC..  trans79.3-49.3175.900000112.9L413 G414 W424L413-G417 PolarHBondContact O-N 3.41Å; G414-G417 PolarHBondContact O-N 3.11Å; G417-W424 PolarHBondContact O-N 3.22Å
418S76Confident81.9Confident43 Ų4348.5 Ų48.530%0.30127%0.265SS..EExtended strand (participates in β ladder)trans-153.2145.7175.756.90000113I416 L422I416-S418 WeakPolarHBondContact CG2-O 3.41Å; I416-S418 PolarHBondContact O-N 2.96Å; S418-L422 CarbonylContact C-O 3.57Å; S418-L422 WeakPolarHBondContact CA-O 3.33Å; S418-L422 WeakPolarHBondContact CB-O 3.41Å
419I78.1Confident81.4Confident88 Ų8850.6 Ų50.645%0.45128%0.283SS..EExtended strand (participates in β ladder)trans-124.8105.4169.5-61.5171.3000107.9L413 I416 K421 L422 W424L413-I419 HydrophobicContact CD2-CD1 4.38Å; I416-I419 HydrophobicContact CD1-CD1 4.46Å; I416-I419 HydrophobicContact CG2-CD1 4.21Å; I416-I419 HydrophobicContact CG2-CG1 3.65Å; I419-K421 PolarHBondContact O-N 3.19Å; I419-L422 PolarHBondContact N-O 3.17Å; I419-L422 WeakPolarHBondContact O-CB 3.29Å; I419-L422 PolarHBondContact O-N 3Å; I419-W424 HydrophobicContact CD1-CZ2 4.12Å
420G77.9Confident81.1Confident65 Ų6550.1 Ų50.167%0.6728%0.284SS*.THydrogen-bonded Turntrans58.2-121.6-172.100000110.9L422G420-L422 VanDerWaalsContact C-N 3.35Å
421K74.7Confident80.9Confident167 Ų16750.4 Ų50.473%0.72629%0.285SS*.THydrogen-bonded Turntrans-87.7-0178.6-60.1-176.9-179.3-179.90114Q370 I419 Y423Q370-K421 PolarHBondContact OE1-O 3.27Å; I419-K421 PolarHBondContact O-N 3.19Å; K421-Y423 VanDerWaalsContact O-CD2 3.28Å; K421-Y423 WeakPolarHBondContact O-CD2 3.44Å
422L81.6Confident80.8Confident46 Ų4653.3 Ų53.324%0.24130%0.301CS..EExtended strand (participates in β ladder)trans-93.1119178.3-63.8174.6000109.4L372 P373 I376 S418 I419 G420 W424L372-L422 HydrophobicContact CD2-CD2 3.62Å; L372-L422 HydrophobicContact CG-CD2 3.97Å; P373-L422 HydrophobicContact CG-CB 4.14Å; P373-L422 HydrophobicContact CG-CD2 3.95Å; I376-L422 HydrophobicContact CD1-CD1 4.04Å; S418-L422 CarbonylContact C-O 3.57Å; S418-L422 WeakPolarHBondContact CA-O 3.33Å; S418-L422 WeakPolarHBondContact CB-O 3.41Å; I419-L422 PolarHBondContact N-O 3.17Å; I419-L422 WeakPolarHBondContact O-CB 3.29Å; I419-L422 PolarHBondContact O-N 3Å; G420-L422 VanDerWaalsContact C-N 3.35Å; L422-W424 HydrophobicContact CB-CZ2 4.16Å; L422-W424 HydrophobicContact CD1-CZ2 4.18Å
423Y77.9Confident80.8Confident11 Ų1152.8 Ų52.84%0.04331%0.306CS..EExtended strand (participates in β ladder)trans-106.1118.6179.4-62.6-102.5000110.2E299 L302 F339 P373 K421 F425E299-Y423 HydrophobicContact CG-CE1 4.43Å; E299-Y423 HydrophobicContact CG-CE2 4.41Å; E299-Y423 WeakPolarHBondContact CG-OH 3.46Å; E299-Y423 VanDerWaalsContact OE1-CE2 3.3Å; E299-Y423 WeakPolarHBondContact OE1-CE2 3.37Å; E299-Y423 VanDerWaalsContact OE1-CZ 3.28Å; E299-Y423 PolarHBondContact OE1-OH 3.3Å; L302-Y423 HydrophobicContact CD1-CE1 4.06Å; F339-Y423 HydrophobicContact CD2-CD1 4.33Å; F339-Y423 AromaticContact CD2-CE1 3.83Å; F339-Y423 HydrophobicContact CD2-CE1 3.83Å; F339-Y423 HydrophobicContact CE2-CE1 4.04Å; F339-Y423 HydrophobicContact CG-CD1 4.37Å; F339-Y423 HydrophobicContact CG-CE1 4.27Å; P373-Y423 WeakPolarHBondContact CB-O 3.48Å; P373-Y423 WeakPolarHBondContact CG-O 3.18Å; K421-Y423 VanDerWaalsContact O-CD2 3.28Å; K421-Y423 WeakPolarHBondContact O-CD2 3.44Å; Y423-F425 PolarHBondContact O-N 2.9Å; Y423-F425 VanDerWaalsContact O-N 3.08Å
424W83Confident80.9Confident12 Ų1254.2 Ų54.25%0.04531%0.314CS..  trans-86.339.7176.4-46.3102.9000110.3I76 P373 I376 L413 G417 I419 L422I76-W424 HydrophobicContact CD1-CB 4.35Å; P373-W424 HydrophobicContact CB-CD2 4.25Å; P373-W424 HydrophobicContact CB-CE3 3.67Å; P373-W424 HydrophobicContact CB-CH2 4.46Å; P373-W424 HydrophobicContact CB-CZ3 3.83Å; P373-W424 WeakPolarHBondContact O-CZ3 3.46Å; I376-W424 HydrophobicContact CB-CH2 4.03Å; I376-W424 HydrophobicContact CB-CZ3 4.26Å; I376-W424 HydrophobicContact CG2-CH2 3.72Å; I376-W424 HydrophobicContact CG2-CZ3 4.28Å; L413-W424 HydrophobicContact CB-CB 4.06Å; L413-W424 HydrophobicContact CB-CD2 3.85Å; L413-W424 HydrophobicContact CB-CE3 3.93Å; L413-W424 HydrophobicContact CB-CG 3.87Å; L413-W424 HydrophobicContact CD1-CD2 4.37Å; L413-W424 HydrophobicContact CD1-CE3 3.78Å; L413-W424 HydrophobicContact CD1-CH2 4.29Å; L413-W424 HydrophobicContact CD1-CZ3 3.71Å; L413-W424 HydrophobicContact CD2-CD2 3.9Å; L413-W424 HydrophobicContact CD2-CE3 4.13Å; L413-W424 HydrophobicContact CD2-CG 4.44Å; L413-W424 HydrophobicContact CD2-CH2 4.14Å; L413-W424 HydrophobicContact CD2-CZ2 3.93Å; L413-W424 HydrophobicContact CD2-CZ3 4.21Å; L413-W424 HydrophobicContact CG-CD2 4.24Å; L413-W424 HydrophobicContact CG-CE3 4.16Å; L413-W424 HydrophobicContact CG-CZ3 4.4Å; L413-W424 WeakPolarHBondContact O-CB 3.34Å; G417-W424 PolarHBondContact O-N 3.22Å; I419-W424 HydrophobicContact CD1-CZ2 4.12Å; L422-W424 HydrophobicContact CB-CZ2 4.16Å; L422-W424 HydrophobicContact CD1-CZ2 4.18Å
425F75.9Confident81.3Confident86 Ų8656.5 Ų56.538%0.37732%0.321SS..  trans-118.1131175.2173.7-95.2000108.1F339 L366 Y423F339-F425 HydrophobicContact CD1-CD1 4.35Å; F339-F425 HydrophobicContact CD1-CG 4.39Å; F339-F425 AromaticContact CE1-CD1 3.84Å; F339-F425 HydrophobicContact CE1-CD1 3.84Å; F339-F425 HydrophobicContact CE1-CE1 4.32Å; F339-F425 HydrophobicContact CE1-CG 4.31Å; L366-F425 HydrophobicContact CD2-CE1 4.16Å; Y423-F425 PolarHBondContact O-N 2.9Å; Y423-F425 VanDerWaalsContact O-N 3.08Å
426M82.4Confident81.8Confident12 Ų1254.7 Ų54.76%0.05932%0.317CS..  trans-111128.7172.6-167.3173.5-66.900109.4T73 I76 V369 V374 A430 N431 L434T73-M426 HydrophobicContact CG2-SD 4.47Å; I76-M426 HydrophobicContact CG2-CB 4.4Å; V369-M426 HydrophobicContact CG1-CE 4.2Å; V369-M426 HydrophobicContact CG1-CG 4.43Å; V369-M426 HydrophobicContact CG2-CG 4.21Å; V374-M426 HydrophobicContact CB-CE 4.44Å; V374-M426 HydrophobicContact CG1-CE 4.29Å; V374-M426 HydrophobicContact CG2-CE 3.29Å; M426-A430 HydrophobicContact CG-CB 3.95Å; M426-A430 HydrophobicContact SD-CB 4.27Å; M426-N431 HydrophobicContact CB-CB 4.03Å; M426-N431 HydrophobicContact CG-CB 3.87Å; M426-N431 WeakPolarHBondContact SD-CA 3.42Å; M426-N431 HydrophobicContact SD-CB 3.83Å; M426-N431 PolarHBondContact SD-N 3.47Å; M426-N431 VanDerWaalsContact SD-N 3.43Å; M426-L434 HydrophobicContact CE-CD2 3.88Å; M426-L434 HydrophobicContact SD-CB 4.47Å; M426-L434 HydrophobicContact SD-CD2 4.27Å
427P78Confident82.4Confident2 Ų255.1 Ų55.11%0.01332%0.32CS..  trans-46.6138.3170.3-28.432.9000111.6L366 Q367 V369 S429 A430 N431L366-P427 WeakPolarHBondContact O-CB 3.3Å; L366-P427 WeakPolarHBondContact O-CG 3.49Å; Q367-P427 VanDerWaalsContact C-CG 3.46Å; V369-P427 HydrophobicContact CG2-CG 4.27Å; P427-S429 VanDerWaalsContact C-N 3.28Å; P427-S429 PolarHBondContact O-N 3.45Å; P427-A430 HydrophobicContact CB-CB 4.23Å; P427-A430 PolarHBondContact O-N 3.31Å; P427-A430 VanDerWaalsContact O-N 3.08Å; P427-N431 PolarHBondContact O-N 3.43Å
428P76.1Confident83.3Confident101 Ų10153.8 Ų53.866%0.65631%0.307SS*.Hα-helixtrans-54.5-40-175.4-29.235.3000114.4L432P428-L432 VanDerWaalsContact O-CB 3.26Å; P428-L432 WeakPolarHBondContact O-CB 3.44Å; P428-L432 PolarHBondContact O-N 2.95Å
429S79.3Confident84.1Confident82 Ų8252.5 Ų52.557%0.57330%0.296SS*.Hα-helixtrans-65.2-43.4178.450.70000112.3P427 L432 A433P427-S429 VanDerWaalsContact C-N 3.28Å; P427-S429 PolarHBondContact O-N 3.45Å; S429-L432 PolarHBondContact O-N 2.87Å; S429-A433 WeakPolarHBondContact O-CB 3.29Å; S429-A433 PolarHBondContact O-N 3.31Å
430A87.1Confident84.9Confident21 Ų2149.2 Ų49.217%0.17428%0.28CS..Hα-helixtrans-70.7-39.9177.500000112.6V369 M426 P427 L432 A433 L434V369-A430 HydrophobicContact CG2-CB 3.01Å; M426-A430 HydrophobicContact CG-CB 3.95Å; M426-A430 HydrophobicContact SD-CB 4.27Å; P427-A430 HydrophobicContact CB-CB 4.23Å; P427-A430 PolarHBondContact O-N 3.31Å; P427-A430 VanDerWaalsContact O-N 3.08Å; A430-L432 VanDerWaalsContact C-N 3.29Å; A430-L432 PolarHBondContact O-N 3.49Å; A430-A433 PolarHBondContact O-N 3.35Å; A430-L434 WeakPolarHBondContact O-CB 3.02Å; A430-L434 PolarHBondContact O-N 3.2Å
431N87.1Confident85.7Confident6 Ų648.3 Ų48.33%0.03226%0.26CS..Hα-helixtrans-62.4-42.3175.1-165.568.4000110.7T73 Q77 M426 P427 R435T73-N431 WeakPolarHBondContact CA-OD1 3.48Å; T73-N431 VanDerWaalsContact CB-OD1 3.29Å; T73-N431 WeakPolarHBondContact CB-OD1 3.33Å; T73-N431 PolarHBondContact O-ND2 2.86Å; T73-N431 PolarHBondContact O-OD1 3.48Å; Q77-N431 PolarHBondContact OE1-ND2 3.39Å; M426-N431 HydrophobicContact CB-CB 4.03Å; M426-N431 HydrophobicContact CG-CB 3.87Å; M426-N431 WeakPolarHBondContact SD-CA 3.42Å; M426-N431 HydrophobicContact SD-CB 3.83Å; M426-N431 PolarHBondContact SD-N 3.47Å; M426-N431 VanDerWaalsContact SD-N 3.43Å; P427-N431 PolarHBondContact O-N 3.43Å; N431-R435 WeakPolarHBondContact O-CB 3.19Å; N431-R435 PolarHBondContact O-N 2.91Å
432L84.3Confident86.6Confident71 Ų7140.4 Ų40.437%0.37223%0.225SC..Hα-helixtrans-60.8-51.9173.9-175.365.4000111.1P428 S429 A430 L434 R435 E436P428-L432 VanDerWaalsContact O-CB 3.26Å; P428-L432 WeakPolarHBondContact O-CB 3.44Å; P428-L432 PolarHBondContact O-N 2.95Å; S429-L432 PolarHBondContact O-N 2.87Å; A430-L432 VanDerWaalsContact C-N 3.29Å; A430-L432 PolarHBondContact O-N 3.49Å; L432-L434 PolarHBondContact O-N 3.39Å; L432-R435 PolarHBondContact O-N 3.32Å; L432-E436 HydrophobicContact CD1-CG 4.15Å; L432-E436 WeakPolarHBondContact CD1-OE1 3.49Å; L432-E436 HydrophobicContact CG-CG 4.36Å; L432-E436 WeakPolarHBondContact O-CB 3.45Å; L432-E436 VanDerWaalsContact O-CG 3.28Å; L432-E436 WeakPolarHBondContact O-CG 3.31Å; L432-E436 PolarHBondContact O-N 3.14Å
433A90.5Very high87.2Confident57 Ų5738.2 Ų38.247%0.47121%0.214SC..Hα-helixtrans-60.6-45.3-178.400000112.9S429 A430 E436 L437S429-A433 WeakPolarHBondContact O-CB 3.29Å; S429-A433 PolarHBondContact O-N 3.31Å; A430-A433 PolarHBondContact O-N 3.35Å; A433-E436 PolarHBondContact O-N 2.95Å; A433-L437 WeakPolarHBondContact O-CB 3.26Å; A433-L437 PolarHBondContact O-N 2.86Å
434L92.6Very high88Confident37 Ų3737.8 Ų37.819%0.19421%0.213CC..Hα-helixtrans-69.3-37.6-179.8-159.673.9000111.4L69 T73 V374 M426 A430 L432 G438L69-L434 HydrophobicContact CD2-CD1 4.46Å; L69-L434 HydrophobicContact CD2-CD2 4.29Å; L69-L434 HydrophobicContact CD2-CG 4.32Å; T73-L434 HydrophobicContact CG2-CB 3.87Å; T73-L434 HydrophobicContact CG2-CD2 3.73Å; T73-L434 HydrophobicContact CG2-CG 4.03Å; V374-L434 HydrophobicContact CG1-CD2 4.24Å; M426-L434 HydrophobicContact CE-CD2 3.88Å; M426-L434 HydrophobicContact SD-CB 4.47Å; M426-L434 HydrophobicContact SD-CD2 4.27Å; A430-L434 WeakPolarHBondContact O-CB 3.02Å; A430-L434 PolarHBondContact O-N 3.2Å; L432-L434 PolarHBondContact O-N 3.39Å; L434-G438 PolarHBondContact O-N 3.29Å
435R90Very high88.5Confident53 Ų5337.2 Ų37.220%0.221%0.211CC..Hα-helixtrans-63.3-47.7173.7-172.8175.963.2175.91.2111.5F70 T73 N431 L432 G438 I439F70-R435 HydrophobicContact CD2-CG 3.5Å; F70-R435 HydrophobicContact CE2-CG 3.79Å; T73-R435 HydrophobicContact CG2-CB 4.49Å; T73-R435 WeakPolarHBondContact OG1-CA 3.11Å; T73-R435 VanDerWaalsContact OG1-CB 3.25Å; T73-R435 WeakPolarHBondContact OG1-CB 3.33Å; T73-R435 WeakPolarHBondContact OG1-CG 3.31Å; N431-R435 WeakPolarHBondContact O-CB 3.19Å; N431-R435 PolarHBondContact O-N 2.91Å; L432-R435 PolarHBondContact O-N 3.32Å; R435-G438 PolarHBondContact O-N 3.35Å; R435-I439 VanDerWaalsContact O-CG2 3.31Å; R435-I439 WeakPolarHBondContact O-CG2 3.33Å; R435-I439 PolarHBondContact O-N 3.37Å
436E90.3Very high89.3Confident78 Ų7833.2 Ų33.236%0.36419%0.193SC..Hα-helixtrans-63.8-43.8178.7-74.6-169.417900111.6I33 L432 A433 G438 I439 V440I33-E436 HydrophobicContact CD1-CG 3.68Å; L432-E436 HydrophobicContact CD1-CG 4.15Å; L432-E436 WeakPolarHBondContact CD1-OE1 3.49Å; L432-E436 HydrophobicContact CG-CG 4.36Å; L432-E436 WeakPolarHBondContact O-CB 3.45Å; L432-E436 VanDerWaalsContact O-CG 3.28Å; L432-E436 WeakPolarHBondContact O-CG 3.31Å; L432-E436 PolarHBondContact O-N 3.14Å; A433-E436 PolarHBondContact O-N 2.95Å; E436-G438 PolarHBondContact O-N 2.93Å; E436-I439 WeakPolarHBondContact O-CG2 3.4Å; E436-I439 PolarHBondContact O-N 3.49Å; E436-V440 WeakPolarHBondContact O-CB 3.45Å; E436-V440 WeakPolarHBondContact O-CG2 3.35Å; E436-V440 PolarHBondContact O-N 2.83Å
437L94Very high89.8Confident92 Ų9232.6 Ų32.648%0.48219%0.19SC..Hα-helixtrans-59.4-47.5174.3-175.468.4000111.2A433 I439 V440 L441A433-L437 WeakPolarHBondContact O-CB 3.26Å; A433-L437 PolarHBondContact O-N 2.86Å; L437-I439 PolarHBondContact O-N 3Å; L437-V440 PolarHBondContact O-N 2.87Å; L437-L441 HydrophobicContact CG-CD1 4.25Å; L437-L441 VanDerWaalsContact O-CG 3.31Å; L437-L441 WeakPolarHBondContact O-CG 3.4Å; L437-L441 PolarHBondContact O-N 2.91Å
438G93.4Very high90.6Very high0 Ų033.1 Ų33.10%019%0.193CC..Hα-helixtrans-58.2-48.9-179.900000112.9G66 L434 R435 E436 L441 F442G66-G438 CarbonylContact C-O 3.23Å; G66-G438 VanDerWaalsContact C-O 3.23Å; G66-G438 WeakPolarHBondContact CA-O 3.34Å; G66-G438 CarbonylContact O-C 3.56Å; G66-G438 VanDerWaalsContact O-C 3.22Å; G66-G438 WeakPolarHBondContact O-CA 3.34Å; G66-G438 VanDerWaalsContact O-O 3.14Å; L434-G438 PolarHBondContact O-N 3.29Å; R435-G438 PolarHBondContact O-N 3.35Å; E436-G438 PolarHBondContact O-N 2.93Å; G438-L441 PolarHBondContact O-N 2.89Å; G438-F442 WeakPolarHBondContact O-CB 3.5Å; G438-F442 PolarHBondContact O-N 3.21Å
439I91.7Very high91.3Very high16 Ų1630.3 Ų30.38%0.08217%0.17CC..Hα-helixtrans-70.4-34179.6-171.6163.4000112.7I33 F70 T133 R435 E436 L437 F442 L443I33-I439 HydrophobicContact CG2-CB 4.32Å; I33-I439 HydrophobicContact CG2-CD1 3.99Å; I33-I439 HydrophobicContact CG2-CG1 3.94Å; I33-I439 HydrophobicContact CG2-CG2 3.44Å; I33-I439 VanDerWaalsContact CG2-CG2 3.44Å; F70-I439 HydrophobicContact CB-CB 4.44Å; F70-I439 HydrophobicContact CD1-CB 4.41Å; F70-I439 HydrophobicContact CD2-CB 3.7Å; F70-I439 HydrophobicContact CD2-CD1 4.32Å; F70-I439 HydrophobicContact CD2-CG1 4.47Å; F70-I439 HydrophobicContact CD2-CG2 4.32Å; F70-I439 HydrophobicContact CE1-CD1 4Å; F70-I439 HydrophobicContact CE1-CG1 4.49Å; F70-I439 HydrophobicContact CE2-CB 4.01Å; F70-I439 HydrophobicContact CE2-CD1 3.75Å; F70-I439 HydrophobicContact CE2-CG1 4.39Å; F70-I439 HydrophobicContact CG-CB 3.95Å; F70-I439 HydrophobicContact CZ-CB 4.48Å; F70-I439 HydrophobicContact CZ-CD1 3.59Å; F70-I439 HydrophobicContact CZ-CG1 4.41Å; T133-I439 HydrophobicContact CG2-CD1 4.03Å; T133-I439 HydrophobicContact CG2-CG1 4.23Å; R435-I439 VanDerWaalsContact O-CG2 3.31Å; R435-I439 WeakPolarHBondContact O-CG2 3.33Å; R435-I439 PolarHBondContact O-N 3.37Å; E436-I439 WeakPolarHBondContact O-CG2 3.4Å; E436-I439 PolarHBondContact O-N 3.49Å; L437-I439 PolarHBondContact O-N 3Å; I439-F442 PolarHBondContact O-N 3.45Å; I439-L443 HydrophobicContact CD1-CD1 4.09Å; I439-L443 HydrophobicContact CG1-CD1 3.68Å; I439-L443 HydrophobicContact CG1-CG 3.87Å; I439-L443 VanDerWaalsContact O-CB 3.29Å; I439-L443 WeakPolarHBondContact O-CB 3.32Å; I439-L443 WeakPolarHBondContact O-CG 3.29Å; I439-L443 PolarHBondContact O-N 3.45Å
440V94.7Very high91.9Very high18 Ų1826.5 Ų26.511%0.10914%0.143CC..Hα-helixtrans-62-47.4174.1168.90000109.8A15 L19 V36 E436 L437 S444A15-V440 HydrophobicContact CB-CG1 3.71Å; L19-V440 HydrophobicContact CD2-CG2 4.09Å; V36-V440 HydrophobicContact CG1-CG1 4.4Å; V36-V440 HydrophobicContact CG2-CG2 4.13Å; E436-V440 WeakPolarHBondContact O-CB 3.45Å; E436-V440 WeakPolarHBondContact O-CG2 3.35Å; E436-V440 PolarHBondContact O-N 2.83Å; L437-V440 PolarHBondContact O-N 2.87Å; V440-S444 WeakPolarHBondContact O-CB 3.41Å; V440-S444 PolarHBondContact O-N 3.23Å; V440-S444 PolarHBondContact O-OG 2.9Å
441L95.5Very high92Very high47 Ų4725.5 Ų25.525%0.24614%0.135CC..Hα-helixtrans-60.2-47.7177-68.7175.9000111.7I62 L437 G438 V445I62-L441 HydrophobicContact CG2-CB 3.88Å; I62-L441 HydrophobicContact CG2-CD2 3.9Å; I62-L441 HydrophobicContact CG2-CG 4.36Å; L437-L441 HydrophobicContact CG-CD1 4.25Å; L437-L441 VanDerWaalsContact O-CG 3.31Å; L437-L441 WeakPolarHBondContact O-CG 3.4Å; L437-L441 PolarHBondContact O-N 2.91Å; G438-L441 PolarHBondContact O-N 2.89Å; L441-V445 PolarHBondContact O-N 2.95Å
442F93.8Very high92Very high0 Ų026.2 Ų26.20%014%0.144CC..Hα-helixtrans-61.4-54.2179176-101.6000112.4Q63 L67 T133 L136 G438 I439 S444 V445 V446Q63-F442 HydrophobicContact CG-CD2 3.64Å; Q63-F442 HydrophobicContact CG-CE2 3.81Å; Q63-F442 WeakPolarHBondContact O-CD2 3.48Å; L67-F442 HydrophobicContact CB-CD2 3.78Å; L67-F442 HydrophobicContact CB-CE2 4.22Å; L67-F442 HydrophobicContact CB-CG 4.44Å; L67-F442 HydrophobicContact CD1-CD2 4.26Å; L67-F442 HydrophobicContact CD1-CE2 4.16Å; L67-F442 HydrophobicContact CD1-CZ 4.43Å; L67-F442 HydrophobicContact CD2-CE2 4.2Å; L67-F442 HydrophobicContact CG-CD2 4.44Å; L67-F442 HydrophobicContact CG-CE2 4.44Å; T133-F442 HydrophobicContact CG2-CD1 3.63Å; T133-F442 HydrophobicContact CG2-CE1 3.51Å; L136-F442 HydrophobicContact CD2-CE1 4.05Å; L136-F442 HydrophobicContact CD2-CZ 4.2Å; L136-F442 HydrophobicContact CG-CE1 4.43Å; L136-F442 HydrophobicContact CG-CZ 4.2Å; G438-F442 WeakPolarHBondContact O-CB 3.5Å; G438-F442 PolarHBondContact O-N 3.21Å; I439-F442 PolarHBondContact O-N 3.45Å; F442-S444 VanDerWaalsContact C-N 3.29Å; F442-S444 PolarHBondContact O-N 3.47Å; F442-V445 PolarHBondContact O-N 3.17Å; F442-V446 HydrophobicContact CD1-CG2 4.33Å; F442-V446 HydrophobicContact CD2-CG2 4.42Å; F442-V446 HydrophobicContact CE1-CG2 3.92Å; F442-V446 HydrophobicContact CE2-CG2 4.03Å; F442-V446 HydrophobicContact CZ-CG2 3.76Å; F442-V446 WeakPolarHBondContact O-CG2 3.38Å; F442-V446 PolarHBondContact O-N 2.92Å; F442-V446 VanDerWaalsContact O-N 3.09Å
443L93.1Very high92.1Very high1 Ų127.5 Ų27.51%0.00515%0.151CC..Hα-helixtrans-67.9-28.8-177.7-72.5-177.8000112.8I33 V36 L37 T133 Y160 I439 V445 G447I33-L443 HydrophobicContact CG2-CD1 4.37Å; V36-L443 HydrophobicContact CB-CB 4.12Å; V36-L443 HydrophobicContact CG1-CB 3.92Å; L37-L443 HydrophobicContact CB-CD2 4.38Å; L37-L443 HydrophobicContact CD1-CD2 4.24Å; T133-L443 HydrophobicContact CG2-CD2 3.65Å; T133-L443 HydrophobicContact CG2-CG 4.12Å; Y160-L443 HydrophobicContact CE1-CD2 4.36Å; I439-L443 HydrophobicContact CD1-CD1 4.09Å; I439-L443 HydrophobicContact CG1-CD1 3.68Å; I439-L443 HydrophobicContact CG1-CG 3.87Å; I439-L443 VanDerWaalsContact O-CB 3.29Å; I439-L443 WeakPolarHBondContact O-CB 3.32Å; I439-L443 WeakPolarHBondContact O-CG 3.29Å; I439-L443 PolarHBondContact O-N 3.45Å; L443-V445 VanDerWaalsContact C-N 3.34Å; L443-G447 PolarHBondContact O-N 3.28Å
444S95.4Very high92.1Very high2 Ų226 Ų261%0.01413%0.134CC..Hα-helixtrans-61.8-45.7176.2-64.50000110.7V36 V440 F442 L448V36-S444 VanDerWaalsContact CG1-OG 3.29Å; V36-S444 WeakPolarHBondContact CG1-OG 3.4Å; V440-S444 WeakPolarHBondContact O-CB 3.41Å; V440-S444 PolarHBondContact O-N 3.23Å; V440-S444 PolarHBondContact O-OG 2.9Å; F442-S444 VanDerWaalsContact C-N 3.29Å; F442-S444 PolarHBondContact O-N 3.47Å; S444-L448 WeakPolarHBondContact O-CB 3.35Å; S444-L448 PolarHBondContact O-N 3.05Å
445V94.4Very high92Very high0 Ų027.4 Ų27.40%014%0.144CC..Hα-helixtrans-69.4-46178.5178.20000111L11 L59 I62 Q63 L441 F442 L443 G447 L448 K449L11-V445 HydrophobicContact CD1-CG2 4.39Å; L11-V445 HydrophobicContact CD2-CG2 3.83Å; L59-V445 HydrophobicContact CB-CG1 3.89Å; L59-V445 HydrophobicContact CD2-CG1 4.23Å; L59-V445 HydrophobicContact CD2-CG2 4.04Å; I62-V445 HydrophobicContact CB-CG2 4.28Å; I62-V445 HydrophobicContact CG2-CG2 3.97Å; Q63-V445 HydrophobicContact CB-CB 3.99Å; Q63-V445 HydrophobicContact CB-CG1 3.91Å; Q63-V445 HydrophobicContact CB-CG2 4.21Å; Q63-V445 HydrophobicContact CG-CB 4.39Å; Q63-V445 HydrophobicContact CG-CG1 4.32Å; L441-V445 PolarHBondContact O-N 2.95Å; F442-V445 PolarHBondContact O-N 3.17Å; L443-V445 VanDerWaalsContact C-N 3.34Å; V445-G447 PolarHBondContact O-N 3.08Å; V445-L448 PolarHBondContact O-N 2.75Å; V445-K449 HydrophobicContact CG1-CD 4.02Å; V445-K449 HydrophobicContact CG1-CG 4.38Å; V445-K449 WeakPolarHBondContact O-CG 3.5Å; V445-K449 PolarHBondContact O-N 3.1Å
446V92Very high92.1Very high1 Ų129 Ų291%0.00616%0.157CC..Hα-helixtrans-59-47.41791710000111.3L37 L136 F442 S450L37-V446 HydrophobicContact CD1-CB 4.46Å; L37-V446 HydrophobicContact CD1-CG1 3.8Å; L136-V446 HydrophobicContact CD2-CG1 3.92Å; L136-V446 HydrophobicContact CD2-CG2 4.47Å; F442-V446 HydrophobicContact CD1-CG2 4.33Å; F442-V446 HydrophobicContact CD2-CG2 4.42Å; F442-V446 HydrophobicContact CE1-CG2 3.92Å; F442-V446 HydrophobicContact CE2-CG2 4.03Å; F442-V446 HydrophobicContact CZ-CG2 3.76Å; F442-V446 WeakPolarHBondContact O-CG2 3.38Å; F442-V446 PolarHBondContact O-N 2.92Å; F442-V446 VanDerWaalsContact O-N 3.09Å; V446-S450 WeakPolarHBondContact O-CB 3.5Å; V446-S450 PolarHBondContact O-N 3.48Å; V446-S450 PolarHBondContact O-OG 3Å
447G93.6Very high92.2Very high0 Ų026.4 Ų26.40%015%0.146CC..Hα-helixtrans-64.1-44.6178.800000111.6L37 G40 I41 L443 V445 K449 S450 G451L37-G447 WeakPolarHBondContact O-CA 3.32Å; G40-G447 CarbonylContact C-O 3.53Å; G40-G447 VanDerWaalsContact C-O 3.23Å; G40-G447 CarbonylContact O-C 3.57Å; I41-G447 WeakPolarHBondContact CA-O 3.36Å; I41-G447 PolarHBondContact N-O 2.96Å; L443-G447 PolarHBondContact O-N 3.28Å; V445-G447 PolarHBondContact O-N 3.08Å; G447-K449 PolarHBondContact O-N 3.25Å; G447-S450 PolarHBondContact O-N 2.89Å; G447-G451 PolarHBondContact O-N 3.08Å
448L94.5Very high92Very high13 Ų1324.6 Ų24.67%0.06814%0.137CC..Hα-helixtrans-58.2-47178.3-172.376000111.9I10 L11 V14 G40 V43 V47 L54 L59 S444 V445 S450 G451I10-L448 HydrophobicContact CG2-CD1 3.71Å; I10-L448 HydrophobicContact CG2-CD2 4.19Å; L11-L448 HydrophobicContact CD2-CD2 4.23Å; V14-L448 HydrophobicContact CG2-CD1 3.9Å; G40-L448 WeakPolarHBondContact O-CA 3.45Å; G40-L448 PolarHBondContact O-N 2.93Å; V43-L448 HydrophobicContact CG1-CD1 4.17Å; V47-L448 HydrophobicContact CG2-CD1 4.37Å; L54-L448 HydrophobicContact CD1-CD2 3.56Å; L54-L448 HydrophobicContact CD1-CG 4.46Å; L59-L448 HydrophobicContact CD1-CD2 4.42Å; L59-L448 HydrophobicContact CD2-CD2 3.88Å; S444-L448 WeakPolarHBondContact O-CB 3.35Å; S444-L448 PolarHBondContact O-N 3.05Å; V445-L448 PolarHBondContact O-N 2.75Å; L448-S450 VanDerWaalsContact C-N 3.32Å; L448-S450 PolarHBondContact O-N 2.94Å; L448-G451 PolarHBondContact O-N 2.8Å
449K91.2Very high91.9Very high42 Ų4229.4 Ų29.418%0.18317%0.166CC..Hα-helixtrans-64.7-35.5177-71.6178.3170.5-175.70112.7Q63 D154 V445 G447 G451Q63-K449 VanDerWaalsContact OE1-NZ 3.1Å; D154-K449 WeakPolarHBondContact OD1-CD 3.22Å; D154-K449 IonicContact OD1-NZ 2.67Å; V445-K449 HydrophobicContact CG1-CD 4.02Å; V445-K449 HydrophobicContact CG1-CG 4.38Å; V445-K449 WeakPolarHBondContact O-CG 3.5Å; V445-K449 PolarHBondContact O-N 3.1Å; G447-K449 PolarHBondContact O-N 3.25Å; K449-G451 VanDerWaalsContact C-N 3.32Å
450S90.2Very high91.8Very high1 Ų134.6 Ų34.61%0.00719%0.194CC..Hα-helixtrans-74.3-23.4178.8-55.30000112.9G157 M158 V446 G447 L448 G452 F454G157-S450 VanDerWaalsContact C-OG 3.26Å; M158-S450 PolarHBondContact N-OG 3.12Å; V446-S450 WeakPolarHBondContact O-CB 3.5Å; V446-S450 PolarHBondContact O-N 3.48Å; V446-S450 PolarHBondContact O-OG 3Å; G447-S450 PolarHBondContact O-N 2.89Å; L448-S450 VanDerWaalsContact C-N 3.32Å; L448-S450 PolarHBondContact O-N 2.94Å; S450-G452 PolarHBondContact O-N 2.75Å; S450-F454 WeakPolarHBondContact O-CB 3.11Å; S450-F454 PolarHBondContact O-N 2.8Å; S450-F454 VanDerWaalsContact O-N 3.15Å
451G89.5Confident91.6Very high0 Ų035.8 Ų35.80%021%0.21CC..Hα-helixtrans-66.1-31.7-166.500000116.1I41 H45 G447 L448 K449I41-G451 VanDerWaalsContact O-CA 3.25Å; I41-G451 WeakPolarHBondContact O-CA 3.3Å; H45-G451 WeakPolarHBondContact CA-O 3.3Å; H45-G451 WeakPolarHBondContact CB-O 3.22Å; G447-G451 PolarHBondContact O-N 3.08Å; L448-G451 PolarHBondContact O-N 2.8Å; K449-G451 VanDerWaalsContact C-N 3.32Å
452G86.7Confident91.4Very high22 Ų2238.6 Ų38.623%0.22722%0.222CC..Hα-helixtrans-59.2-50.6-178.700000112.3S450S450-G452 PolarHBondContact O-N 2.75Å
453D87.9Confident91.3Very high97 Ų9738.6 Ų38.652%0.51922%0.222SC..Hα-helixtrans-97.8-11.5-174.1-65.8-44.5000114.1M158 V455 N456 T457M158-D453 HydrophobicContact CE-CB 3.66Å; M158-D453 HydrophobicContact SD-CB 4.25Å; D453-V455 PolarHBondContact O-N 3.29Å; D453-N456 PolarHBondContact O-N 3.17Å; D453-N456 VanDerWaalsContact O-N 3.09Å; D453-T457 PolarHBondContact O-N 3.34Å; D453-T457 PolarHBondContact O-OG1 3.48Å; D453-T457 VanDerWaalsContact O-OG1 3.11Å
454F90.8Very high91.3Very high25 Ų2544.5 Ų44.511%0.1125%0.253CS..Hα-helixtrans-52.4-49.5-171.8-175-91.1000113.5I41 M158 A161 M162 S450 T457 L458I41-F454 HydrophobicContact CD1-CD2 3.78Å; I41-F454 HydrophobicContact CD1-CE2 3.83Å; I41-F454 HydrophobicContact CD1-CG 4.26Å; I41-F454 HydrophobicContact CD1-CZ 4.36Å; I41-F454 HydrophobicContact CG1-CD2 4.34Å; I41-F454 HydrophobicContact CG1-CG 4.49Å; I41-F454 HydrophobicContact CG2-CB 3.76Å; I41-F454 HydrophobicContact CG2-CD1 3.68Å; I41-F454 HydrophobicContact CG2-CD2 4.25Å; I41-F454 HydrophobicContact CG2-CE1 4.35Å; I41-F454 HydrophobicContact CG2-CG 3.62Å; M158-F454 HydrophobicContact CG-CB 4.5Å; M158-F454 HydrophobicContact CG-CD2 3.94Å; A161-F454 HydrophobicContact CB-CD2 4.41Å; A161-F454 HydrophobicContact CB-CE2 3.83Å; M162-F454 HydrophobicContact CE-CD2 3.94Å; M162-F454 HydrophobicContact CE-CE2 3.98Å; M162-F454 HydrophobicContact CE-CG 4.42Å; M162-F454 HydrophobicContact CE-CZ 4.5Å; M162-F454 HydrophobicContact CG-CD2 4.29Å; M162-F454 HydrophobicContact CG-CE2 3.5Å; M162-F454 VanDerWaalsContact CG-CE2 3.5Å; M162-F454 HydrophobicContact CG-CZ 3.97Å; S450-F454 WeakPolarHBondContact O-CB 3.11Å; S450-F454 PolarHBondContact O-N 2.8Å; S450-F454 VanDerWaalsContact O-N 3.15Å; F454-T457 PolarHBondContact O-N 3.08Å; F454-L458 HydrophobicContact CE1-CD2 4.08Å; F454-L458 VanDerWaalsContact O-CB 3.3Å; F454-L458 WeakPolarHBondContact O-CB 3.31Å; F454-L458 PolarHBondContact O-N 2.98Å
455V90.1Very high91.2Very high67 Ų6747 Ų4741%0.40627%0.27SS..Hα-helixtrans-65.6-41.6-1781790000110.7D453 L458 V459D453-V455 PolarHBondContact O-N 3.29Å; V455-L458 PolarHBondContact O-N 3.1Å; V455-V459 HydrophobicContact CG1-CG2 4.36Å; V455-V459 WeakPolarHBondContact O-CB 3.4Å; V455-V459 WeakPolarHBondContact O-CG2 3.46Å; V455-V459 PolarHBondContact O-N 3.39Å
456N91Very high91.3Very high87 Ų8747.7 Ų47.747%0.46527%0.273SS..Hα-helixtrans-65.3-46.1179.1-173.244.5000111D453 L458 V459 N460 G461D453-N456 PolarHBondContact O-N 3.17Å; D453-N456 VanDerWaalsContact O-N 3.09Å; N456-L458 VanDerWaalsContact C-N 3.29Å; N456-L458 PolarHBondContact O-N 3.33Å; N456-V459 PolarHBondContact O-N 3.03Å; N456-N460 WeakPolarHBondContact O-CA 3.28Å; N456-N460 WeakPolarHBondContact O-CB 3.21Å; N456-N460 PolarHBondContact O-N 3.1Å; N456-N460 PolarHBondContact OD1-ND2 3.41Å; N456-G461 PolarHBondContact O-N 3.16Å; N456-G461 VanDerWaalsContact O-N 3.1Å
457T91.9Very high91.4Very high23 Ų2349.1 Ų49.114%0.14128%0.28CS..Hα-helixtrans-63.3-36.1177.1-56.70000111.9M158 M162 D453 F454 G461 G463 W466M158-T457 HydrophobicContact SD-CG2 3.93Å; M158-T457 PolarHBondContact SD-OG1 2.83Å; M162-T457 HydrophobicContact CE-CG2 3.57Å; M162-T457 HydrophobicContact SD-CG2 4.3Å; D453-T457 PolarHBondContact O-N 3.34Å; D453-T457 PolarHBondContact O-OG1 3.48Å; D453-T457 VanDerWaalsContact O-OG1 3.11Å; F454-T457 PolarHBondContact O-N 3.08Å; T457-G461 CarbonylContact O-C 3.15Å; T457-G461 WeakPolarHBondContact O-CA 3.12Å; T457-G461 PolarHBondContact O-N 2.89Å; T457-G463 WeakPolarHBondContact O-CA 3.14Å; T457-G463 PolarHBondContact O-N 2.96Å; T457-W466 HydrophobicContact CG2-CE3 4.21Å; T457-W466 HydrophobicContact CG2-CH2 3.62Å; T457-W466 HydrophobicContact CG2-CZ2 4.21Å; T457-W466 HydrophobicContact CG2-CZ3 3.61Å
458L91.4Very high91.5Very high55 Ų5550.7 Ų50.729%0.28830%0.296SS..Hα-helixtrans-70.7-43.3178.9-178.363000113M162 F454 V455 N456 I467M162-L458 HydrophobicContact CE-CB 4.13Å; F454-L458 HydrophobicContact CE1-CD2 4.08Å; F454-L458 VanDerWaalsContact O-CB 3.3Å; F454-L458 WeakPolarHBondContact O-CB 3.31Å; F454-L458 PolarHBondContact O-N 2.98Å; V455-L458 PolarHBondContact O-N 3.1Å; N456-L458 VanDerWaalsContact C-N 3.29Å; N456-L458 PolarHBondContact O-N 3.33Å; L458-I467 HydrophobicContact CD1-CD1 3.66Å
459V91.6Very high91.6Very high100 Ų10051.8 Ų51.861%0.60630%0.3SS*.Hα-helixtrans-91.4-42.5-1721790000112.1V455 N456V455-V459 HydrophobicContact CG1-CG2 4.36Å; V455-V459 WeakPolarHBondContact O-CB 3.4Å; V455-V459 WeakPolarHBondContact O-CG2 3.46Å; V455-V459 PolarHBondContact O-N 3.39Å; N456-V459 PolarHBondContact O-N 3.03Å
460N89.2Confident91.8Very high125 Ų12549.8 Ų49.867%0.66829%0.291SS*.THydrogen-bonded Turntrans-110.5-16.1-172.9-56.4-43.2000113.1N456N456-N460 WeakPolarHBondContact O-CA 3.28Å; N456-N460 WeakPolarHBondContact O-CB 3.21Å; N456-N460 PolarHBondContact O-N 3.1Å; N456-N460 PolarHBondContact OD1-ND2 3.41Å
461G89.6Confident92.1Very high44 Ų4451.4 Ų51.445%0.45430%0.304SS..SBendtrans-104.1-157.3-177.900000113.6N456 T457 G463N456-G461 PolarHBondContact O-N 3.16Å; N456-G461 VanDerWaalsContact O-N 3.1Å; T457-G461 CarbonylContact O-C 3.15Å; T457-G461 WeakPolarHBondContact O-CA 3.12Å; T457-G461 PolarHBondContact O-N 2.89Å; G461-G463 PolarHBondContact O-N 3.1Å
462E90.7Very high92.4Very high105 Ų10555.2 Ų55.249%0.49133%0.325SS..THydrogen-bonded Turntrans-82.37.6-177.7-62.3-171.216800114.4L464 S465 W466E462-L464 PolarHBondContact O-N 2.85Å; E462-L464 VanDerWaalsContact O-N 3.14Å; E462-S465 WeakPolarHBondContact O-CA 3.43Å; E462-S465 VanDerWaalsContact O-CB 3.31Å; E462-S465 WeakPolarHBondContact O-CB 3.33Å; E462-S465 PolarHBondContact O-N 2.86Å; E462-W466 HydrophobicContact CB-CZ2 4.42Å; E462-W466 VanDerWaalsContact CB-NE1 3.32Å; E462-W466 VanDerWaalsContact O-CD1 3.24Å; E462-W466 PolarHBondContact O-N 2.97Å; E462-W466 PolarHBondContact OE2-NE1 2.8Å; E462-W466 VanDerWaalsContact OE2-NE1 3.12Å
463G91.5Very high92.9Very high0 Ų054.2 Ų54.20%031%0.314CS..Hα-helixtrans-59.6-33-170.900000114M162 T457 G461 W466 I467M162-G463 WeakPolarHBondContact SD-CA 3.4Å; T457-G463 WeakPolarHBondContact O-CA 3.14Å; T457-G463 PolarHBondContact O-N 2.96Å; G461-G463 PolarHBondContact O-N 3.1Å; G463-W466 PolarHBondContact O-N 2.91Å; G463-I467 WeakPolarHBondContact O-CG1 3.26Å; G463-I467 PolarHBondContact O-N 3.28Å
464L93.2Very high93.3Very high126 Ų12649.7 Ų49.766%0.6629%0.29SS*.Hα-helixtrans-64.1-40.9172.4-104.4139.1000112.6E462 I467 G468E462-L464 PolarHBondContact O-N 2.85Å; E462-L464 VanDerWaalsContact O-N 3.14Å; L464-I467 WeakPolarHBondContact O-CB 3.4Å; L464-I467 PolarHBondContact O-N 3.3Å; L464-G468 PolarHBondContact O-N 3.23Å; L464-G468 VanDerWaalsContact O-N 3.07Å
465S94.9Very high93.6Very high54 Ų5449.8 Ų49.838%0.37830%0.295SS..Hα-helixtrans-64.9-42.4174.2-55.30000110.6E462 I467 G468 Y469E462-S465 WeakPolarHBondContact O-CA 3.43Å; E462-S465 VanDerWaalsContact O-CB 3.31Å; E462-S465 WeakPolarHBondContact O-CB 3.33Å; E462-S465 PolarHBondContact O-N 2.86Å; S465-I467 VanDerWaalsContact C-N 3.32Å; S465-I467 PolarHBondContact O-N 3.36Å; S465-G468 WeakPolarHBondContact O-CA 3.45Å; S465-G468 PolarHBondContact O-N 3.02Å; S465-Y469 WeakPolarHBondContact O-CD2 3.06Å; S465-Y469 PolarHBondContact O-N 2.95Å
466W95.2Very high93.9Very high15 Ų1549.2 Ų49.26%0.05729%0.292CS..Hα-helixtrans-61.9-40177.9-61.10.4000112.3V121 I125 M158 M162 T457 E462 G463 Y469 G470V121-W466 HydrophobicContact CB-CZ2 4.34Å; V121-W466 HydrophobicContact CG1-CD2 3.69Å; V121-W466 HydrophobicContact CG1-CE3 4.21Å; V121-W466 HydrophobicContact CG1-CG 4.14Å; V121-W466 HydrophobicContact CG1-CH2 4.1Å; V121-W466 HydrophobicContact CG1-CZ2 3.57Å; V121-W466 HydrophobicContact CG1-CZ3 4.4Å; V121-W466 HydrophobicContact CG2-CH2 3.96Å; V121-W466 HydrophobicContact CG2-CZ2 3.76Å; I125-W466 HydrophobicContact CD1-CB 3.74Å; I125-W466 HydrophobicContact CD1-CG 3.86Å; I125-W466 HydrophobicContact CG1-CB 4.09Å; I125-W466 HydrophobicContact CG1-CG 4.43Å; M158-W466 HydrophobicContact SD-CZ3 4.31Å; M162-W466 HydrophobicContact CE-CE3 4.4Å; M162-W466 HydrophobicContact CE-CZ3 4.39Å; M162-W466 HydrophobicContact SD-CD2 4.32Å; M162-W466 HydrophobicContact SD-CE3 3.45Å; M162-W466 HydrophobicContact SD-CZ3 4Å; T457-W466 HydrophobicContact CG2-CE3 4.21Å; T457-W466 HydrophobicContact CG2-CH2 3.62Å; T457-W466 HydrophobicContact CG2-CZ2 4.21Å; T457-W466 HydrophobicContact CG2-CZ3 3.61Å; E462-W466 HydrophobicContact CB-CZ2 4.42Å; E462-W466 VanDerWaalsContact CB-NE1 3.32Å; E462-W466 VanDerWaalsContact O-CD1 3.24Å; E462-W466 PolarHBondContact O-N 2.97Å; E462-W466 PolarHBondContact OE2-NE1 2.8Å; E462-W466 VanDerWaalsContact OE2-NE1 3.12Å; G463-W466 PolarHBondContact O-N 2.91Å; W466-Y469 PolarHBondContact O-N 3.31Å; W466-G470 PolarHBondContact O-N 3.42Å
467I95.1Very high94.2Very high31 Ų3145 Ų4516%0.15927%0.269CS..Hα-helixtrans-58.6-47.6171-76.8166.6000110.9M162 F166 L458 G463 L464 S465 Y469 G470 A471M162-I467 HydrophobicContact CB-CG1 4.19Å; F166-I467 HydrophobicContact CD1-CG2 4.25Å; F166-I467 HydrophobicContact CD2-CB 4.42Å; F166-I467 HydrophobicContact CD2-CG1 4.3Å; F166-I467 HydrophobicContact CD2-CG2 3.55Å; F166-I467 HydrophobicContact CE1-CG2 3.94Å; F166-I467 HydrophobicContact CE2-CB 4.23Å; F166-I467 HydrophobicContact CE2-CD1 4.22Å; F166-I467 HydrophobicContact CE2-CG1 4.08Å; F166-I467 HydrophobicContact CE2-CG2 3.19Å; F166-I467 HydrophobicContact CG-CG2 4.07Å; F166-I467 HydrophobicContact CZ-CG2 3.4Å; L458-I467 HydrophobicContact CD1-CD1 3.66Å; G463-I467 WeakPolarHBondContact O-CG1 3.26Å; G463-I467 PolarHBondContact O-N 3.28Å; L464-I467 WeakPolarHBondContact O-CB 3.4Å; L464-I467 PolarHBondContact O-N 3.3Å; S465-I467 VanDerWaalsContact C-N 3.32Å; S465-I467 PolarHBondContact O-N 3.36Å; I467-Y469 PolarHBondContact O-N 2.91Å; I467-G470 PolarHBondContact O-N 2.92Å; I467-A471 PolarHBondContact O-N 3.44Å
468G95.3Very high94.4Very high33 Ų3344 Ų4434%0.3426%0.263SS..Hα-helixtrans-60.1-44.9178.200000112.6L464 S465 G470 A471 L472L464-G468 PolarHBondContact O-N 3.23Å; L464-G468 VanDerWaalsContact O-N 3.07Å; S465-G468 WeakPolarHBondContact O-CA 3.45Å; S465-G468 PolarHBondContact O-N 3.02Å; G468-G470 VanDerWaalsContact C-N 3.35Å; G468-G470 PolarHBondContact O-N 3.09Å; G468-A471 WeakPolarHBondContact O-CB 3.4Å; G468-A471 PolarHBondContact O-N 2.81Å; G468-L472 WeakPolarHBondContact O-CG 3.47Å; G468-L472 PolarHBondContact O-N 3.14Å
469Y96.3Very high94.7Very high35 Ų3543.4 Ų43.414%0.13726%0.26CS..Hα-helixtrans-62.7-41.5174.9-58.7-33.3000112L111 F115 I117 I125 S465 W466 I467 A471 L472 I473L111-Y469 HydrophobicContact CD1-CD1 4.45Å; L111-Y469 HydrophobicContact CD2-CD1 4Å; L111-Y469 HydrophobicContact CD2-CE1 4.48Å; F115-Y469 HydrophobicContact CD1-CE1 4.36Å; F115-Y469 WeakPolarHBondContact CD1-OH 3.32Å; F115-Y469 HydrophobicContact CD2-CD1 4.41Å; F115-Y469 AromaticContact CD2-CE1 3.64Å; F115-Y469 HydrophobicContact CD2-CE1 3.64Å; F115-Y469 AromaticContact CD2-CZ 4Å; F115-Y469 HydrophobicContact CE1-CE1 4.49Å; F115-Y469 AromaticContact CE2-CE1 3.8Å; F115-Y469 HydrophobicContact CE2-CE1 3.8Å; F115-Y469 AromaticContact CG-CE1 3.94Å; F115-Y469 HydrophobicContact CG-CE1 3.94Å; F115-Y469 AromaticContact CG-CZ 3.84Å; F115-Y469 WeakPolarHBondContact CG-OH 3.31Å; F115-Y469 HydrophobicContact CZ-CE1 4.23Å; I117-Y469 HydrophobicContact CD1-CD2 3.39Å; I117-Y469 HydrophobicContact CD1-CE2 3.45Å; I117-Y469 VanDerWaalsContact CD1-CE2 3.45Å; I117-Y469 HydrophobicContact CD1-CG 3.97Å; I117-Y469 HydrophobicContact CG1-CD2 4.27Å; I117-Y469 HydrophobicContact CG1-CE2 3.9Å; I125-Y469 HydrophobicContact CD1-CD2 4.04Å; S465-Y469 WeakPolarHBondContact O-CD2 3.06Å; S465-Y469 PolarHBondContact O-N 2.95Å; W466-Y469 PolarHBondContact O-N 3.31Å; I467-Y469 PolarHBondContact O-N 2.91Å; Y469-A471 VanDerWaalsContact C-N 3.34Å; Y469-A471 PolarHBondContact O-N 2.68Å; Y469-L472 PolarHBondContact O-N 3.35Å; Y469-I473 WeakPolarHBondContact O-CG1 3.16Å; Y469-I473 PolarHBondContact O-N 3.13Å
470G96.3Very high94.9Very high0 Ų041.5 Ų41.50%025%0.248CC..Hα-helixtrans-58.1-46.9173.900000111.7A129 W466 I467 G468 L472 I473 T474A129-G470 WeakPolarHBondContact CB-O 3.31Å; W466-G470 PolarHBondContact O-N 3.42Å; I467-G470 PolarHBondContact O-N 2.92Å; G468-G470 VanDerWaalsContact C-N 3.35Å; G468-G470 PolarHBondContact O-N 3.09Å; G470-L472 VanDerWaalsContact C-N 3.3Å; G470-L472 PolarHBondContact O-N 2.89Å; G470-I473 PolarHBondContact O-N 2.8Å; G470-T474 PolarHBondContact O-N 3.24Å; G470-T474 PolarHBondContact O-OG1 2.88Å; G470-T474 VanDerWaalsContact O-OG1 3.05Å
471A95.9Very high95.3Very high35 Ų3535.5 Ų35.529%0.28922%0.216SC..Hα-helixtrans-59.5-39176.600000112.5F166 I467 G468 Y469 T474 A475F166-A471 HydrophobicContact CD1-CB 4.41Å; I467-A471 PolarHBondContact O-N 3.44Å; G468-A471 WeakPolarHBondContact O-CB 3.4Å; G468-A471 PolarHBondContact O-N 2.81Å; Y469-A471 VanDerWaalsContact C-N 3.34Å; Y469-A471 PolarHBondContact O-N 2.68Å; A471-T474 PolarHBondContact O-N 2.87Å; A471-A475 WeakPolarHBondContact O-CB 3.48Å; A471-A475 PolarHBondContact O-N 2.96Å
472L96.2Very high95.6Very high81 Ų8133.4 Ų33.442%0.42420%0.195SC..Hα-helixtrans-66.2-45.3175.4-69.5174.2000112.2L111 G468 Y469 G470 T474 A475 V476L111-L472 HydrophobicContact CD1-CB 4.32Å; L111-L472 HydrophobicContact CD2-CD1 4.08Å; G468-L472 WeakPolarHBondContact O-CG 3.47Å; G468-L472 PolarHBondContact O-N 3.14Å; Y469-L472 PolarHBondContact O-N 3.35Å; G470-L472 VanDerWaalsContact C-N 3.3Å; G470-L472 PolarHBondContact O-N 2.89Å; L472-T474 PolarHBondContact O-N 3.36Å; L472-A475 PolarHBondContact O-N 3.14Å; L472-V476 HydrophobicContact CD2-CG2 4.43Å; L472-V476 WeakPolarHBondContact O-CB 3.17Å; L472-V476 WeakPolarHBondContact O-CG2 3.42Å; L472-V476 PolarHBondContact O-N 3.28Å
473I97Very high95.9Very high1 Ų130.8 Ų30.81%0.00518%0.184CC..Hα-helixtrans-62.4-32.8177.9-68.1165.9000111.1V107 T108 L111 I125 F126 A129 V130 Y469 G470 P477V107-I473 HydrophobicContact CG1-CG1 3.95Å; T108-I473 HydrophobicContact CG2-CD1 4.33Å; L111-I473 HydrophobicContact CD1-CD1 3.99Å; L111-I473 HydrophobicContact CD1-CG1 3.73Å; I125-I473 HydrophobicContact CG2-CD1 3.85Å; F126-I473 HydrophobicContact CD2-CG2 4.04Å; A129-I473 HydrophobicContact CB-CB 3.86Å; A129-I473 HydrophobicContact CB-CG2 3.74Å; V130-I473 HydrophobicContact CG1-CG2 4.03Å; Y469-I473 WeakPolarHBondContact O-CG1 3.16Å; Y469-I473 PolarHBondContact O-N 3.13Å; G470-I473 PolarHBondContact O-N 2.8Å; I473-P477 WeakPolarHBondContact O-CD 3.23Å; I473-P477 WeakPolarHBondContact O-CG 3.21Å
474T96.7Very high96.2Very high1 Ų133.6 Ų33.61%0.00620%0.198CC..Hα-helixtrans-76.3-53.5173.9-51.30000111.9A129 G470 A471 L472 L478A129-T474 PolarHBondContact O-OG1 2.84Å; G470-T474 PolarHBondContact O-N 3.24Å; G470-T474 PolarHBondContact O-OG1 2.88Å; G470-T474 VanDerWaalsContact O-OG1 3.05Å; A471-T474 PolarHBondContact O-N 2.87Å; L472-T474 PolarHBondContact O-N 3.36Å; T474-L478 HydrophobicContact CG2-CD1 3.82Å; T474-L478 WeakPolarHBondContact O-CD1 3.48Å; T474-L478 VanDerWaalsContact O-CG 3.22Å; T474-L478 WeakPolarHBondContact O-CG 3.4Å
475A95.8Very high96.3Very high27 Ų2727.6 Ų27.622%0.22317%0.167CC..Hα-helixtrans-73.2-45.4-167.500000112.7A471 L472 L478 I479A471-A475 WeakPolarHBondContact O-CB 3.48Å; A471-A475 PolarHBondContact O-N 2.96Å; L472-A475 PolarHBondContact O-N 3.14Å; A475-L478 PolarHBondContact O-N 3.13Å; A475-I479 HydrophobicContact CB-CD1 4.01Å; A475-I479 VanDerWaalsContact O-CB 3.28Å; A475-I479 WeakPolarHBondContact O-CB 3.47Å; A475-I479 WeakPolarHBondContact O-CG1 3.37Å; A475-I479 PolarHBondContact O-N 2.94Å
476V96.8Very high96.3Very high55 Ų5527.5 Ų27.533%0.33316%0.158SC..Hα-helixtrans-60.2-50.4-173.3173.50000111.9I103 V107 L472 T480I103-V476 HydrophobicContact CG2-CG1 4.41Å; V107-V476 HydrophobicContact CG2-CB 4.1Å; V107-V476 HydrophobicContact CG2-CG1 3.75Å; L472-V476 HydrophobicContact CD2-CG2 4.43Å; L472-V476 WeakPolarHBondContact O-CB 3.17Å; L472-V476 WeakPolarHBondContact O-CG2 3.42Å; L472-V476 PolarHBondContact O-N 3.28Å; V476-T480 WeakPolarHBondContact O-CB 2.83Å; V476-T480 PolarHBondContact O-N 3.33Å; V476-T480 VanDerWaalsContact O-N 3.12Å; V476-T480 PolarHBondContact O-OG1 2.94Å
477P97.2Very high96.2Very high0 Ų032.7 Ų32.70%019%0.185CC..Hα-helixtrans-64.5-44.4178.2-20.333.2000112.8I100 I103 I473 V481I100-P477 HydrophobicContact CG2-CB 4.03Å; I103-P477 HydrophobicContact CB-CB 4.13Å; I103-P477 HydrophobicContact CB-CG 4.39Å; I103-P477 HydrophobicContact CG2-CB 4.02Å; I103-P477 HydrophobicContact CG2-CG 3.98Å; I473-P477 WeakPolarHBondContact O-CD 3.23Å; I473-P477 WeakPolarHBondContact O-CG 3.21Å; P477-V481 WeakPolarHBondContact O-CB 3.41Å; P477-V481 WeakPolarHBondContact O-CG2 3.44Å; P477-V481 PolarHBondContact O-N 3.38Å
478L97.2Very high96.1Very high0 Ų037.4 Ų37.40%021%0.209CC..Hα-helixtrans-67-44.6-175.8-68.3174.9000112.4I100 I171 T174 T474 A475 G482 L500 M504I100-L478 HydrophobicContact CD1-CD2 4.41Å; I100-L478 HydrophobicContact CG2-CD2 4.44Å; I171-L478 HydrophobicContact CB-CD1 3.82Å; I171-L478 HydrophobicContact CD1-CD1 4.42Å; I171-L478 HydrophobicContact CG1-CD1 3.92Å; T174-L478 HydrophobicContact CG2-CB 3.63Å; T474-L478 HydrophobicContact CG2-CD1 3.82Å; T474-L478 WeakPolarHBondContact O-CD1 3.48Å; T474-L478 VanDerWaalsContact O-CG 3.22Å; T474-L478 WeakPolarHBondContact O-CG 3.4Å; A475-L478 PolarHBondContact O-N 3.13Å; L478-G482 WeakPolarHBondContact O-CA 3.11Å; L478-G482 PolarHBondContact O-N 3.02Å; L478-L500 HydrophobicContact CD2-CB 4.14Å; L478-L500 HydrophobicContact CD2-CD2 3.77Å; L478-L500 HydrophobicContact CD2-CG 4.38Å; L478-M504 HydrophobicContact CD1-CE 3.81Å; L478-M504 HydrophobicContact CD1-CG 4.16Å; L478-M504 HydrophobicContact CD2-CE 3.49Å; L478-M504 VanDerWaalsContact CD2-CE 3.49Å; L478-M504 HydrophobicContact CD2-CG 3.73Å; L478-M504 HydrophobicContact CD2-SD 4.44Å; L478-M504 HydrophobicContact CG-CE 3.35Å; L478-M504 HydrophobicContact CG-CG 4.3Å
479I96.6Very high95.9Very high43 Ų4336.1 Ų36.122%0.22120%0.196CC..Hα-helixtrans-66.8-49.5-179.2-66.1172.7000109.2T174 M177 A475 V481 G482 I483T174-I479 HydrophobicContact CG2-CG1 3.72Å; M177-I479 HydrophobicContact CE-CB 4.15Å; M177-I479 HydrophobicContact CE-CD1 3.69Å; M177-I479 HydrophobicContact CE-CG1 3.53Å; M177-I479 HydrophobicContact CE-CG2 3.64Å; M177-I479 HydrophobicContact SD-CD1 4.25Å; A475-I479 HydrophobicContact CB-CD1 4.01Å; A475-I479 VanDerWaalsContact O-CB 3.28Å; A475-I479 WeakPolarHBondContact O-CB 3.47Å; A475-I479 WeakPolarHBondContact O-CG1 3.37Å; A475-I479 PolarHBondContact O-N 2.94Å; I479-V481 PolarHBondContact O-N 2.92Å; I479-G482 PolarHBondContact O-N 3.22Å; I479-I483 HydrophobicContact CG2-CD1 3.7Å; I479-I483 HydrophobicContact CG2-CG1 4.49Å; I479-I483 WeakPolarHBondContact O-CB 3.39Å; I479-I483 VanDerWaalsContact O-CG1 3.23Å; I479-I483 WeakPolarHBondContact O-CG1 3.39Å; I479-I483 PolarHBondContact O-N 3Å
480T96.7Very high95.6Very high60 Ų6042.9 Ų42.937%0.36823%0.226SC..Hα-helixtrans-60.1-52.1-178-53.60000110.7I103 V476 I483 L484I103-T480 HydrophobicContact CD1-CG2 4.42Å; V476-T480 WeakPolarHBondContact O-CB 2.83Å; V476-T480 PolarHBondContact O-N 3.33Å; V476-T480 VanDerWaalsContact O-N 3.12Å; V476-T480 PolarHBondContact O-OG1 2.94Å; T480-I483 PolarHBondContact O-N 3Å; T480-L484 HydrophobicContact CG2-CD1 4.1Å; T480-L484 VanDerWaalsContact O-CG 3.26Å; T480-L484 WeakPolarHBondContact O-CG 3.18Å; T480-L484 PolarHBondContact O-N 2.88Å
481V97.4Very high95.3Very high0 Ų043.6 Ų43.60%023%0.229CC..Hα-helixtrans-72.8-34.7-177.9-179.50000112F96 L99 I100 I103 P477 I479 I483 L484 A485F96-V481 HydrophobicContact CB-CG1 3.92Å; F96-V481 HydrophobicContact CD1-CG1 3.77Å; F96-V481 HydrophobicContact CG-CG1 4.28Å; L99-V481 HydrophobicContact CB-CG2 4.3Å; L99-V481 HydrophobicContact CD2-CG2 3.9Å; L99-V481 HydrophobicContact CG-CG2 3.8Å; I100-V481 HydrophobicContact CD1-CB 4.06Å; I100-V481 HydrophobicContact CD1-CG1 3.92Å; I100-V481 HydrophobicContact CG1-CB 3.5Å; I100-V481 VanDerWaalsContact CG1-CB 3.5Å; I100-V481 HydrophobicContact CG1-CG1 3.64Å; I100-V481 HydrophobicContact CG1-CG2 3.6Å; I103-V481 HydrophobicContact CD1-CG2 3.71Å; P477-V481 WeakPolarHBondContact O-CB 3.41Å; P477-V481 WeakPolarHBondContact O-CG2 3.44Å; P477-V481 PolarHBondContact O-N 3.38Å; I479-V481 PolarHBondContact O-N 2.92Å; V481-I483 VanDerWaalsContact C-N 3.34Å; V481-I483 PolarHBondContact O-N 3.34Å; V481-L484 PolarHBondContact O-N 3.36Å; V481-A485 VanDerWaalsContact O-CB 3.24Å; V481-A485 WeakPolarHBondContact O-CB 3.39Å; V481-A485 PolarHBondContact O-N 3.13Å
482G96.7Very high95.1Very high0 Ų042.9 Ų42.90%022%0.221CC..Hα-helixtrans-59.4-45.1174.100000112L478 I479 R486 M496L478-G482 WeakPolarHBondContact O-CA 3.11Å; L478-G482 PolarHBondContact O-N 3.02Å; I479-G482 PolarHBondContact O-N 3.22Å; G482-R486 PolarHBondContact O-N 2.85Å; G482-R486 VanDerWaalsContact O-N 3.13Å; G482-M496 WeakPolarHBondContact O-CE 3.34Å
483I96.7Very high95Very high50 Ų5039.2 Ų39.226%0.25620%0.201SC..Hα-helixtrans-63.7-47.9175-69.2169.7000110.6L178 F182 I479 T480 V481 A485 R486 M487L178-I483 HydrophobicContact CD2-CG1 3.93Å; F182-I483 HydrophobicContact CE2-CG1 4.24Å; F182-I483 HydrophobicContact CZ-CB 4.44Å; F182-I483 HydrophobicContact CZ-CG1 4.31Å; F182-I483 HydrophobicContact CZ-CG2 4.28Å; I479-I483 HydrophobicContact CG2-CD1 3.7Å; I479-I483 HydrophobicContact CG2-CG1 4.49Å; I479-I483 WeakPolarHBondContact O-CB 3.39Å; I479-I483 VanDerWaalsContact O-CG1 3.23Å; I479-I483 WeakPolarHBondContact O-CG1 3.39Å; I479-I483 PolarHBondContact O-N 3Å; T480-I483 PolarHBondContact O-N 3Å; V481-I483 VanDerWaalsContact C-N 3.34Å; V481-I483 PolarHBondContact O-N 3.34Å; I483-A485 PolarHBondContact O-N 3.35Å; I483-R486 PolarHBondContact O-N 2.93Å; I483-M487 HydrophobicContact CG2-CG 4.21Å; I483-M487 HydrophobicContact CG2-SD 3.53Å; I483-M487 VanDerWaalsContact CG2-SD 3.53Å; I483-M487 WeakPolarHBondContact O-CB 3.44Å; I483-M487 WeakPolarHBondContact O-CG 3.36Å; I483-M487 PolarHBondContact O-N 3.07Å
484L96.4Very high94.7Very high59 Ų5939.3 Ų39.331%0.30920%0.202SC..Hα-helixtrans-61.2-43.3179.3-71.1171.8000112.5F96 L99 T480 V481 R486 M487 L488F96-L484 HydrophobicContact CE1-CB 4.42Å; L99-L484 HydrophobicContact CD2-CD1 4.3Å; T480-L484 HydrophobicContact CG2-CD1 4.1Å; T480-L484 VanDerWaalsContact O-CG 3.26Å; T480-L484 WeakPolarHBondContact O-CG 3.18Å; T480-L484 PolarHBondContact O-N 2.88Å; V481-L484 PolarHBondContact O-N 3.36Å; L484-R486 VanDerWaalsContact C-N 3.28Å; L484-R486 PolarHBondContact O-N 2.7Å; L484-M487 PolarHBondContact O-N 3.05Å; L484-L488 HydrophobicContact CB-CD1 4.44Å; L484-L488 HydrophobicContact CD2-CD1 3.88Å; L484-L488 HydrophobicContact CD2-CG 4.39Å; L484-L488 VanDerWaalsContact O-CB 3.3Å; L484-L488 WeakPolarHBondContact O-CB 3.47Å; L484-L488 PolarHBondContact O-N 3.21Å
485A95.3Very high94.4Very high0 Ų040 Ų400%021%0.206CC..Hα-helixtrans-61.9-37.4177.500000111.5F96 V481 I483 A489 K490 M491 M496 M499F96-A485 HydrophobicContact CD1-CB 4.08Å; F96-A485 HydrophobicContact CD2-CB 4.29Å; F96-A485 HydrophobicContact CE1-CB 4.07Å; F96-A485 HydrophobicContact CE2-CB 4.29Å; F96-A485 HydrophobicContact CG-CB 4.19Å; F96-A485 HydrophobicContact CZ-CB 4.18Å; V481-A485 VanDerWaalsContact O-CB 3.24Å; V481-A485 WeakPolarHBondContact O-CB 3.39Å; V481-A485 PolarHBondContact O-N 3.13Å; I483-A485 PolarHBondContact O-N 3.35Å; A485-A489 CarbonylContact O-C 3.59Å; A485-A489 WeakPolarHBondContact O-CA 3.3Å; A485-A489 VanDerWaalsContact O-CB 3.25Å; A485-A489 WeakPolarHBondContact O-CB 3.36Å; A485-A489 PolarHBondContact O-N 2.87Å; A485-K490 PolarHBondContact O-N 2.88Å; A485-M491 HydrophobicContact CB-CB 4.47Å; A485-M491 HydrophobicContact CB-SD 4.42Å; A485-M491 WeakPolarHBondContact O-CB 3.47Å; A485-M491 PolarHBondContact O-N 3.04Å; A485-M496 HydrophobicContact CB-CG 4.38Å; A485-M496 HydrophobicContact CB-SD 4.42Å; A485-M499 HydrophobicContact CB-CE 4.19Å
486R94.7Very high94.3Very high52 Ų5238.9 Ų38.920%0.19620%0.196CC..Hα-helixtrans-73.9-44.7176.3-170.358.8173.9-165.5-3.1112.4F182 E189 G482 I483 L484 K490 M491 M496F182-R486 HydrophobicContact CB-CG 4.47Å; F182-R486 HydrophobicContact CD1-CB 4.49Å; F182-R486 HydrophobicContact CD1-CG 3.63Å; F182-R486 HydrophobicContact CD2-CB 4.17Å; F182-R486 HydrophobicContact CD2-CG 3.79Å; F182-R486 HydrophobicContact CE1-CB 4.08Å; F182-R486 HydrophobicContact CE1-CG 3.66Å; F182-R486 HydrophobicContact CE2-CB 3.74Å; F182-R486 HydrophobicContact CE2-CG 3.82Å; F182-R486 HydrophobicContact CG-CG 3.7Å; F182-R486 HydrophobicContact CZ-CB 3.69Å; F182-R486 HydrophobicContact CZ-CG 3.75Å; E189-R486 IonicContact OE1-CZ 3.52Å; E189-R486 IonicContact OE1-NH1 3.6Å; E189-R486 PolarHBondContact OE1-NH1 3.23Å; E189-R486 IonicContact OE1-NH2 2.68Å; E189-R486 PolarHBondContact OE1-NH2 3.48Å; E189-R486 IonicContact OE2-NH1 3.19Å; E189-R486 PolarHBondContact OE2-NH1 2.91Å; G482-R486 PolarHBondContact O-N 2.85Å; G482-R486 VanDerWaalsContact O-N 3.13Å; I483-R486 PolarHBondContact O-N 2.93Å; L484-R486 VanDerWaalsContact C-N 3.28Å; L484-R486 PolarHBondContact O-N 2.7Å; R486-K490 WeakPolarHBondContact O-CA 3.28Å; R486-K490 PolarHBondContact O-N 3.29Å; R486-K490 VanDerWaalsContact O-N 3.13Å; R486-M491 WeakPolarHBondContact CD-O 3.42Å; R486-M491 PolarHBondContact NH1-O 3.15Å; R486-M496 HydrophobicContact CB-CE 4.09Å; R486-M496 HydrophobicContact CB-SD 3.81Å; R486-M496 HydrophobicContact CG-SD 4.43Å
487M94.4Very high94.2Very high124 Ų12436.3 Ų36.361%0.61118%0.181SC*.Hα-helixtrans-76.1-50.7-174.5-69.9-177.96800112.9F182 I483 L484F182-M487 HydrophobicContact CE1-CG 4.12Å; F182-M487 HydrophobicContact CZ-CG 4.19Å; I483-M487 HydrophobicContact CG2-CG 4.21Å; I483-M487 HydrophobicContact CG2-SD 3.53Å; I483-M487 VanDerWaalsContact CG2-SD 3.53Å; I483-M487 WeakPolarHBondContact O-CB 3.44Å; I483-M487 WeakPolarHBondContact O-CG 3.36Å; I483-M487 PolarHBondContact O-N 3.07Å; L484-M487 PolarHBondContact O-N 3.05Å
488L93.2Very high93.8Very high129 Ų12936.3 Ų36.368%0.67518%0.181SC*.THydrogen-bonded Turntrans-80.9-40.7-175.6-60.2179.1000111.5L484L484-L488 HydrophobicContact CB-CD1 4.44Å; L484-L488 HydrophobicContact CD2-CD1 3.88Å; L484-L488 HydrophobicContact CD2-CG 4.39Å; L484-L488 VanDerWaalsContact O-CB 3.3Å; L484-L488 WeakPolarHBondContact O-CB 3.47Å; L484-L488 PolarHBondContact O-N 3.21Å
489A89.6Confident93.6Very high7 Ų736.3 Ų36.36%0.05818%0.181CC..THydrogen-bonded Turntrans-99.1-8.3-173.400000115.3R92 F96 A485 M491R92-A489 PolarHBondContact NH1-O 2.82Å; R92-A489 PolarHBondContact NH2-O 2.92Å; F96-A489 HydrophobicContact CE2-CB 3.57Å; F96-A489 HydrophobicContact CZ-CB 3.66Å; A485-A489 CarbonylContact O-C 3.59Å; A485-A489 WeakPolarHBondContact O-CA 3.3Å; A485-A489 VanDerWaalsContact O-CB 3.25Å; A485-A489 WeakPolarHBondContact O-CB 3.36Å; A485-A489 PolarHBondContact O-N 2.87Å; A489-M491 PolarHBondContact O-N 3.16Å; A489-M491 VanDerWaalsContact O-N 3.16Å
490K90.1Very high93.6Very high177 Ų17734.2 Ų34.277%0.7717%0.17SC*.  trans48.837.1-173.2-60.4-176.8-179.9-179.80111.2A485 R486A485-K490 PolarHBondContact O-N 2.88Å; R486-K490 WeakPolarHBondContact O-CA 3.28Å; R486-K490 PolarHBondContact O-N 3.29Å; R486-K490 VanDerWaalsContact O-N 3.13Å
491M90.2Very high93.4Very high14 Ų1431.4 Ų31.47%0.06915%0.153CC..  trans-66.9138.8-173.9-167.9175.3-70.200110.1L93 F96 A485 R486 A489 T495 M496 M499L93-M491 HydrophobicContact CD2-CE 3.61Å; L93-M491 HydrophobicContact CD2-SD 3.62Å; F96-M491 HydrophobicContact CD2-CE 3.63Å; F96-M491 HydrophobicContact CE2-CE 3.85Å; A485-M491 HydrophobicContact CB-CB 4.47Å; A485-M491 HydrophobicContact CB-SD 4.42Å; A485-M491 WeakPolarHBondContact O-CB 3.47Å; A485-M491 PolarHBondContact O-N 3.04Å; R486-M491 WeakPolarHBondContact CD-O 3.42Å; R486-M491 PolarHBondContact NH1-O 3.15Å; A489-M491 PolarHBondContact O-N 3.16Å; A489-M491 VanDerWaalsContact O-N 3.16Å; M491-T495 HydrophobicContact CG-CG2 3.92Å; M491-T495 HydrophobicContact SD-CG2 3.96Å; M491-M496 HydrophobicContact CB-CG 3.76Å; M491-M496 HydrophobicContact CB-SD 4.1Å; M491-M496 HydrophobicContact CG-CG 3.68Å; M491-M496 HydrophobicContact SD-CG 3.7Å; M491-M499 HydrophobicContact SD-CE 4.48Å
492N91.4Very high93Very high21 Ų2131.4 Ų31.411%0.11215%0.153CC..  trans-59.4139.1175.4180-83.6000110.4E189 L494 T495 M496E189-N492 PolarHBondContact O-ND2 2.92Å; E189-N492 WeakPolarHBondContact OE2-CA 3.45Å; E189-N492 PolarHBondContact OE2-ND2 2.83Å; N492-L494 PolarHBondContact O-N 2.76Å; N492-L494 WeakPolarHBondContact OD1-CB 3.39Å; N492-L494 PolarHBondContact OD1-N 3.15Å; N492-T495 WeakPolarHBondContact O-CB 3.26Å; N492-T495 PolarHBondContact O-N 2.87Å; N492-T495 PolarHBondContact OD1-N 3.49Å; N492-M496 WeakPolarHBondContact O-CG 3.5Å; N492-M496 PolarHBondContact O-N 2.9Å
493Y95Very high92.9Very high3 Ų331.4 Ų31.41%0.01215%0.153CC..Hα-helixtrans-63.9-38.4-174.6171.8-105.8000112.8M175 L178 R179 V184 V186 E189 M496 C497 L516M175-Y493 PolarHBondContact O-OH 2.99Å; M175-Y493 VanDerWaalsContact O-OH 3.04Å; L178-Y493 HydrophobicContact CB-CE2 4.43Å; R179-Y493 HydrophobicContact CB-CE1 4.4Å; R179-Y493 HydrophobicContact CB-CE2 3.86Å; R179-Y493 HydrophobicContact CG-CE1 4.26Å; R179-Y493 HydrophobicContact CG-CE2 4.49Å; V184-Y493 HydrophobicContact CB-CG 4.28Å; V184-Y493 HydrophobicContact CG1-CD1 3.74Å; V184-Y493 HydrophobicContact CG1-CD2 4.43Å; V184-Y493 HydrophobicContact CG1-CG 3.69Å; V184-Y493 HydrophobicContact CG2-CD2 4.15Å; V184-Y493 HydrophobicContact CG2-CG 4.17Å; V186-Y493 HydrophobicContact CG2-CE1 4.35Å; E189-Y493 PolarHBondContact OE2-N 3.14Å; Y493-M496 WeakPolarHBondContact O-CB 3.39Å; Y493-M496 PolarHBondContact O-N 2.94Å; Y493-C497 PolarHBondContact O-N 3.22Å; Y493-C497 PolarHBondContact O-SG 2.82Å; Y493-C497 VanDerWaalsContact O-SG 3.39Å; Y493-L516 HydrophobicContact CE1-CD1 3.81Å
494L91.2Very high92.7Very high3 Ų329.1 Ų29.12%0.01614%0.141CC..Hα-helixtrans-67.3-40.4178.2-60175.4000111.3V186 A190 N492 M496 C497 G498 L516 H517 S520 A522 A523V186-L494 HydrophobicContact CG1-CD2 4.11Å; A190-L494 HydrophobicContact CB-CD1 4.01Å; N492-L494 PolarHBondContact O-N 2.76Å; N492-L494 WeakPolarHBondContact OD1-CB 3.39Å; N492-L494 PolarHBondContact OD1-N 3.15Å; L494-M496 VanDerWaalsContact C-N 3.35Å; L494-C497 PolarHBondContact O-N 2.9Å; L494-G498 PolarHBondContact O-N 3.41Å; L494-G498 VanDerWaalsContact O-N 3.09Å; L494-L516 HydrophobicContact CD2-CB 4.04Å; L494-H517 HydrophobicContact CD1-CB 3.99Å; L494-H517 HydrophobicContact CD2-CB 4.32Å; L494-S520 WeakPolarHBondContact CD1-OG 3.18Å; L494-A522 HydrophobicContact CB-CB 3.68Å; L494-A523 WeakPolarHBondContact O-CA 3.29Å
495T89.1Confident92.3Very high16 Ų1626.8 Ų26.810%0.09813%0.129CC..Hα-helixtrans-60.3-44.5171.5-58.30000111L93 H193 M491 N492 G498 M499 S526L93-T495 HydrophobicContact CD1-CG2 4.46Å; L93-T495 HydrophobicContact CD2-CG2 3.59Å; H193-T495 PolarHBondContact CD2-OG1 2.95Å; M491-T495 HydrophobicContact CG-CG2 3.92Å; M491-T495 HydrophobicContact SD-CG2 3.96Å; N492-T495 WeakPolarHBondContact O-CB 3.26Å; N492-T495 PolarHBondContact O-N 2.87Å; N492-T495 PolarHBondContact OD1-N 3.49Å; T495-G498 PolarHBondContact O-N 3.06Å; T495-M499 WeakPolarHBondContact O-CB 3.31Å; T495-M499 PolarHBondContact O-N 3.12Å; T495-S526 WeakPolarHBondContact CA-OG 3.41Å; T495-S526 WeakPolarHBondContact CG2-OG 3.39Å; T495-S526 VanDerWaalsContact O-CB 3.25Å; T495-S526 WeakPolarHBondContact O-CB 3.49Å; T495-S526 PolarHBondContact O-OG 2.89Å
496M94.4Very high91.8Very high3 Ų326.9 Ų26.92%0.01513%0.13CC..Hα-helixtrans-60.7-48.1175.9-76.1174.848.400111.8L178 G482 A485 R486 M491 N492 Y493 L494 G498 M499 L500L178-M496 HydrophobicContact CD1-CE 4.02Å; G482-M496 WeakPolarHBondContact O-CE 3.34Å; A485-M496 HydrophobicContact CB-CG 4.38Å; A485-M496 HydrophobicContact CB-SD 4.42Å; R486-M496 HydrophobicContact CB-CE 4.09Å; R486-M496 HydrophobicContact CB-SD 3.81Å; R486-M496 HydrophobicContact CG-SD 4.43Å; M491-M496 HydrophobicContact CB-CG 3.76Å; M491-M496 HydrophobicContact CB-SD 4.1Å; M491-M496 HydrophobicContact CG-CG 3.68Å; M491-M496 HydrophobicContact SD-CG 3.7Å; N492-M496 WeakPolarHBondContact O-CG 3.5Å; N492-M496 PolarHBondContact O-N 2.9Å; Y493-M496 WeakPolarHBondContact O-CB 3.39Å; Y493-M496 PolarHBondContact O-N 2.94Å; L494-M496 VanDerWaalsContact C-N 3.35Å; M496-G498 VanDerWaalsContact C-N 3.29Å; M496-G498 PolarHBondContact O-N 3.38Å; M496-M499 PolarHBondContact O-N 3.42Å; M496-M499 VanDerWaalsContact O-N 3.11Å; M496-L500 WeakPolarHBondContact O-CG 3.49Å; M496-L500 PolarHBondContact O-N 2.81Å
497C94.2Very high90.9Very high1 Ų128 Ų281%0.00714%0.144CC..Hα-helixtrans-56.2-44.4176.9-71.70000111.7M175 Y493 L494 L500 A501 A513M175-C497 HydrophobicContact CE-CB 4.21Å; M175-C497 WeakPolarHBondContact CE-O 3.4Å; M175-C497 HydrophobicContact SD-CB 3.83Å; Y493-C497 PolarHBondContact O-N 3.22Å; Y493-C497 PolarHBondContact O-SG 2.82Å; Y493-C497 VanDerWaalsContact O-SG 3.39Å; L494-C497 PolarHBondContact O-N 2.9Å; C497-L500 PolarHBondContact O-N 3.18Å; C497-A501 WeakPolarHBondContact O-CB 3.43Å; C497-A501 PolarHBondContact O-N 3.22Å; C497-A513 HydrophobicContact CB-CB 3.68Å
498G89.6Confident90Very high0 Ų023.8 Ų23.80%013%0.126CC..Hα-helixtrans-62.4-42.8174.500000113.5L494 T495 M496 A501 G502 A523 Y527L494-G498 PolarHBondContact O-N 3.41Å; L494-G498 VanDerWaalsContact O-N 3.09Å; T495-G498 PolarHBondContact O-N 3.06Å; M496-G498 VanDerWaalsContact C-N 3.29Å; M496-G498 PolarHBondContact O-N 3.38Å; G498-A501 PolarHBondContact O-N 3.39Å; G498-G502 PolarHBondContact O-N 2.57Å; G498-A523 VanDerWaalsContact CA-O 3.29Å; G498-A523 WeakPolarHBondContact CA-O 3.37Å; G498-Y527 WeakPolarHBondContact O-CA 3.34Å
499M93.6Very high89.7Confident0 Ų017.7 Ų17.70%09%0.093CC..Hα-helixtrans-63.5-45.4176.4178.9-85.9-69.400111.8L93 F96 A97 I100 A485 M491 T495 M496 G502 S503 V530L93-M499 HydrophobicContact CD2-CB 4.27Å; L93-M499 HydrophobicContact CD2-CG 4.4Å; F96-M499 HydrophobicContact CB-CE 3.99Å; F96-M499 HydrophobicContact CB-SD 4.22Å; A97-M499 HydrophobicContact CB-CG 4.47Å; I100-M499 HydrophobicContact CD1-CE 4.45Å; I100-M499 HydrophobicContact CD1-SD 3.6Å; A485-M499 HydrophobicContact CB-CE 4.19Å; M491-M499 HydrophobicContact SD-CE 4.48Å; T495-M499 WeakPolarHBondContact O-CB 3.31Å; T495-M499 PolarHBondContact O-N 3.12Å; M496-M499 PolarHBondContact O-N 3.42Å; M496-M499 VanDerWaalsContact O-N 3.11Å; M499-G502 PolarHBondContact O-N 3.15Å; M499-S503 VanDerWaalsContact O-CB 3.22Å; M499-S503 WeakPolarHBondContact O-CB 3.41Å; M499-S503 PolarHBondContact O-N 2.95Å; M499-S503 PolarHBondContact O-OG 2.9Å; M499-V530 HydrophobicContact CG-CG1 4.14Å
500L96.3Very high89.4Confident0 Ų018.7 Ų18.70%010%0.098CC..Hα-helixtrans-61.6-47.6176.8-65.8-175.9000110.8I100 I171 M175 L178 L478 M496 C497 G502 S503 M504I100-L500 HydrophobicContact CD1-CD2 3.6Å; I171-L500 HydrophobicContact CD1-CB 4.32Å; I171-L500 WeakPolarHBondContact CD1-O 3.42Å; M175-L500 HydrophobicContact CE-CB 4.23Å; M175-L500 HydrophobicContact CG-CD1 4.45Å; L178-L500 HydrophobicContact CD1-CD1 3.62Å; L478-L500 HydrophobicContact CD2-CB 4.14Å; L478-L500 HydrophobicContact CD2-CD2 3.77Å; L478-L500 HydrophobicContact CD2-CG 4.38Å; M496-L500 WeakPolarHBondContact O-CG 3.49Å; M496-L500 PolarHBondContact O-N 2.81Å; C497-L500 PolarHBondContact O-N 3.18Å; L500-G502 PolarHBondContact O-N 2.96Å; L500-S503 WeakPolarHBondContact CA-OG 3.38Å; L500-S503 PolarHBondContact O-N 3.28Å; L500-S503 PolarHBondContact O-OG 2.77Å; L500-M504 PolarHBondContact O-N 3.31Å; L500-M504 VanDerWaalsContact O-N 3.07Å
501A92.1Very high88.6Confident0 Ų012.5 Ų12.50%08%0.08CC..Hα-helixtrans-59.5-45.1176.700000112.1M175 C497 G498 S503 M504 T505 D506 A509 L510 Y527M175-A501 HydrophobicContact CE-CB 3.86Å; C497-A501 WeakPolarHBondContact O-CB 3.43Å; C497-A501 PolarHBondContact O-N 3.22Å; G498-A501 PolarHBondContact O-N 3.39Å; A501-S503 VanDerWaalsContact C-N 3.32Å; A501-S503 PolarHBondContact O-N 3.31Å; A501-M504 PolarHBondContact O-N 3.23Å; A501-T505 PolarHBondContact O-N 3.3Å; A501-T505 VanDerWaalsContact O-N 3.09Å; A501-D506 PolarHBondContact O-N 3.33Å; A501-D506 VanDerWaalsContact O-N 3.08Å; A501-A509 HydrophobicContact CB-CB 3.9Å; A501-L510 HydrophobicContact CB-CB 4.15Å; A501-Y527 HydrophobicContact CB-CD2 3.85Å; A501-Y527 HydrophobicContact CB-CE2 4.27Å
502G89.8Confident88.3Confident0 Ų014.8 Ų14.80%09%0.089CC..Hα-helixtrans-65.6-37.3177.300000112.1G498 M499 L500 M504 T505G498-G502 PolarHBondContact O-N 2.57Å; M499-G502 PolarHBondContact O-N 3.15Å; L500-G502 PolarHBondContact O-N 2.96Å; G502-M504 VanDerWaalsContact C-N 3.28Å; G502-M504 PolarHBondContact O-N 3.19Å; G502-T505 PolarHBondContact O-N 3.13Å
503S94.2Very high88Confident0 Ų013.9 Ų13.90%08%0.084CC..Hα-helixtrans-69-22.6178.478.90000114.1I100 M499 L500 A501 V534 R538I100-S503 VanDerWaalsContact CD1-OG 3.24Å; I100-S503 WeakPolarHBondContact CD1-OG 3.3Å; M499-S503 VanDerWaalsContact O-CB 3.22Å; M499-S503 WeakPolarHBondContact O-CB 3.41Å; M499-S503 PolarHBondContact O-N 2.95Å; M499-S503 PolarHBondContact O-OG 2.9Å; L500-S503 WeakPolarHBondContact CA-OG 3.38Å; L500-S503 PolarHBondContact O-N 3.28Å; L500-S503 PolarHBondContact O-OG 2.77Å; A501-S503 VanDerWaalsContact C-N 3.32Å; A501-S503 PolarHBondContact O-N 3.31Å; S503-V534 WeakPolarHBondContact O-CG1 3.34Å; S503-R538 VanDerWaalsContact O-CZ 3.23Å; S503-R538 PolarHBondContact O-NE 3.37Å; S503-R538 PolarHBondContact O-NH2 3.16Å
504M93.1Very high87Confident3 Ų316.2 Ų16.22%0.01510%0.097CC..THydrogen-bonded Turntrans-103.44.7173.9-68-63.2-178.400112.4I100 V130 T131 I171 L478 L500 A501 G502 D506 R538I100-M504 HydrophobicContact CG2-CE 3.84Å; V130-M504 CarbonylContact C-O 3.42Å; V130-M504 HydrophobicContact CB-SD 3.92Å; V130-M504 HydrophobicContact CG1-SD 3.96Å; T131-M504 PolarHBondContact OG1-O 3.42Å; I171-M504 HydrophobicContact CD1-CB 3.82Å; I171-M504 HydrophobicContact CD1-CG 3.88Å; L478-M504 HydrophobicContact CD1-CE 3.81Å; L478-M504 HydrophobicContact CD1-CG 4.16Å; L478-M504 HydrophobicContact CD2-CE 3.49Å; L478-M504 VanDerWaalsContact CD2-CE 3.49Å; L478-M504 HydrophobicContact CD2-CG 3.73Å; L478-M504 HydrophobicContact CD2-SD 4.44Å; L478-M504 HydrophobicContact CG-CE 3.35Å; L478-M504 HydrophobicContact CG-CG 4.3Å; L500-M504 PolarHBondContact O-N 3.31Å; L500-M504 VanDerWaalsContact O-N 3.07Å; A501-M504 PolarHBondContact O-N 3.23Å; G502-M504 VanDerWaalsContact C-N 3.28Å; G502-M504 PolarHBondContact O-N 3.19Å; M504-D506 HydrophobicContact CB-CB 4.35Å; M504-D506 PolarHBondContact O-N 3.18Å; M504-R538 PolarHBondContact SD-NH2 3.18Å
505T87.7Confident86.7Confident9 Ų922 Ų226%0.05513%0.128CC..THydrogen-bonded Turntrans52.539.8-178.250.80000113.1V130 N132 A501 G502 P507 Y531 V534 M535V130-T505 PolarHBondContact O-OG1 3.37Å; N132-T505 PolarHBondContact ND2-OG1 3.45Å; N132-T505 VanDerWaalsContact ND2-OG1 3.09Å; A501-T505 PolarHBondContact O-N 3.3Å; A501-T505 VanDerWaalsContact O-N 3.09Å; G502-T505 PolarHBondContact O-N 3.13Å; T505-P507 WeakPolarHBondContact O-CD 3.16Å; T505-Y531 HydrophobicContact CG2-CD2 4.05Å; T505-Y531 HydrophobicContact CG2-CE2 3.87Å; T505-V534 HydrophobicContact CG2-CG1 4.46Å; T505-M535 HydrophobicContact CG2-CB 4.2Å; T505-M535 HydrophobicContact CG2-CE 4.11Å
506D85Confident86.6Confident3 Ų322.8 Ų22.82%0.01613%0.132CC..  trans-112.6101.2-171.8-173.9-24.1000111.9I171 A501 M504 P508 A509 L510I171-D506 WeakPolarHBondContact CG2-OD2 3.38Å; A501-D506 PolarHBondContact O-N 3.33Å; A501-D506 VanDerWaalsContact O-N 3.08Å; M504-D506 HydrophobicContact CB-CB 4.35Å; M504-D506 PolarHBondContact O-N 3.18Å; D506-P508 WeakPolarHBondContact OD1-CA 2.72Å; D506-P508 VanDerWaalsContact OD1-CB 3.32Å; D506-P508 WeakPolarHBondContact OD1-CB 3.3Å; D506-P508 WeakPolarHBondContact OD1-CD 3.49Å; D506-P508 WeakPolarHBondContact OD1-CG 3.49Å; D506-P508 VanDerWaalsContact OD1-N 3.08Å; D506-A509 HydrophobicContact CB-CB 3.78Å; D506-A509 VanDerWaalsContact CG-CB 3.45Å; D506-A509 PolarHBondContact O-N 2.87Å; D506-A509 PolarHBondContact OD1-N 3.45Å; D506-L510 PolarHBondContact O-N 3.21Å; D506-L510 VanDerWaalsContact O-N 3.13Å
507P74.7Confident86Confident75 Ų7523.9 Ų23.949%0.48714%0.137SC..Hα-helixtrans-65.4-41.3175.1-19.430.7000114.9T505 A509 L510 A511T505-P507 WeakPolarHBondContact O-CD 3.16Å; P507-A509 VanDerWaalsContact C-N 3.29Å; P507-A509 PolarHBondContact O-N 2.82Å; P507-L510 WeakPolarHBondContact O-CB 3.48Å; P507-L510 PolarHBondContact O-N 2.82Å; P507-L510 VanDerWaalsContact O-N 3.14Å; P507-A511 PolarHBondContact O-N 3.2Å
508P76Confident84.8Confident36 Ų3628.8 Ų28.823%0.23417%0.168CC..Hα-helixtrans-51.1-43.9168.2-29.331.6000114.2I168 D506 L510 A511 F512I168-P508 HydrophobicContact CG2-CB 4.43Å; D506-P508 WeakPolarHBondContact OD1-CA 2.72Å; D506-P508 VanDerWaalsContact OD1-CB 3.32Å; D506-P508 WeakPolarHBondContact OD1-CB 3.3Å; D506-P508 WeakPolarHBondContact OD1-CD 3.49Å; D506-P508 WeakPolarHBondContact OD1-CG 3.49Å; D506-P508 VanDerWaalsContact OD1-N 3.08Å; P508-L510 VanDerWaalsContact C-N 3.33Å; P508-L510 PolarHBondContact O-N 2.88Å; P508-A511 WeakPolarHBondContact O-CB 3.46Å; P508-A511 PolarHBondContact O-N 2.72Å; P508-F512 PolarHBondContact O-N 3.11Å
509A86.9Confident83.7Confident0 Ų034.7 Ų34.70%021%0.205CC..Hα-helixtrans-65.2-37.3176.500000112.2I171 M175 A501 D506 P507 F512 A513I171-A509 HydrophobicContact CD1-CB 3.81Å; I171-A509 HydrophobicContact CG1-CB 4.1Å; I171-A509 HydrophobicContact CG2-CB 3.65Å; M175-A509 HydrophobicContact CE-CB 3.98Å; A501-A509 HydrophobicContact CB-CB 3.9Å; D506-A509 HydrophobicContact CB-CB 3.78Å; D506-A509 VanDerWaalsContact CG-CB 3.45Å; D506-A509 PolarHBondContact O-N 2.87Å; D506-A509 PolarHBondContact OD1-N 3.45Å; P507-A509 VanDerWaalsContact C-N 3.29Å; P507-A509 PolarHBondContact O-N 2.82Å; A509-F512 PolarHBondContact O-N 3.21Å; A509-A513 WeakPolarHBondContact O-CB 3.42Å; A509-A513 PolarHBondContact O-N 3.12Å
510L82.2Confident82.7Confident28 Ų2835.1 Ų35.115%0.14721%0.208CC..Hα-helixtrans-63.8-42171.5176.461.4000112A501 D506 P507 P508 F512 A513 N514 A523 Y527A501-L510 HydrophobicContact CB-CB 4.15Å; D506-L510 PolarHBondContact O-N 3.21Å; D506-L510 VanDerWaalsContact O-N 3.13Å; P507-L510 WeakPolarHBondContact O-CB 3.48Å; P507-L510 PolarHBondContact O-N 2.82Å; P507-L510 VanDerWaalsContact O-N 3.14Å; P508-L510 VanDerWaalsContact C-N 3.33Å; P508-L510 PolarHBondContact O-N 2.88Å; L510-F512 VanDerWaalsContact C-N 3.33Å; L510-F512 PolarHBondContact O-N 3.1Å; L510-A513 PolarHBondContact O-N 3.29Å; L510-N514 WeakPolarHBondContact O-CB 3.49Å; L510-N514 PolarHBondContact O-N 2.99Å; L510-N514 PolarHBondContact O-ND2 2.96Å; L510-A523 HydrophobicContact CD1-CB 4.44Å; L510-Y527 HydrophobicContact CB-CD2 3.84Å; L510-Y527 HydrophobicContact CB-CE2 3.96Å; L510-Y527 HydrophobicContact CB-CG 4.48Å; L510-Y527 HydrophobicContact CD1-CD2 3.98Å; L510-Y527 HydrophobicContact CD1-CG 3.92Å; L510-Y527 HydrophobicContact CD2-CD1 3.7Å; L510-Y527 HydrophobicContact CD2-CD2 3.77Å; L510-Y527 HydrophobicContact CD2-CE1 3.95Å; L510-Y527 HydrophobicContact CD2-CE2 3.99Å; L510-Y527 HydrophobicContact CD2-CG 3.62Å; L510-Y527 HydrophobicContact CG-CD2 4.06Å; L510-Y527 HydrophobicContact CG-CE2 4.47Å; L510-Y527 HydrophobicContact CG-CG 4.2Å
511A73.7Confident81.4Confident47 Ų4736.5 Ų36.539%0.38822%0.222SC..Hα-helixtrans-61.9-43.7177.600000111P507 P508 N514 N515P507-A511 PolarHBondContact O-N 3.2Å; P508-A511 WeakPolarHBondContact O-CB 3.46Å; P508-A511 PolarHBondContact O-N 2.72Å; A511-N514 PolarHBondContact O-N 3.45Å; A511-N515 WeakPolarHBondContact O-CB 3.36Å; A511-N515 VanDerWaalsContact O-CG 3.25Å; A511-N515 PolarHBondContact O-N 3.36Å; A511-N515 PolarHBondContact O-ND2 3.24Å
512F84.3Confident80.6Confident63 Ų6336.5 Ų36.528%0.27622%0.222SC..Hα-helixtrans-58.3-47.6171.1176.5-95.3000111.7L172 M175 P508 A509 L510 N514 N515 L516L172-F512 HydrophobicContact CD2-CB 3.47Å; L172-F512 VanDerWaalsContact CD2-CB 3.47Å; L172-F512 HydrophobicContact CD2-CD1 3.8Å; L172-F512 HydrophobicContact CD2-CD2 4.05Å; L172-F512 HydrophobicContact CD2-CG 3.5Å; L172-F512 VanDerWaalsContact CD2-CG 3.5Å; M175-F512 HydrophobicContact CB-CE1 4.17Å; M175-F512 HydrophobicContact SD-CD1 3.86Å; M175-F512 HydrophobicContact SD-CE1 4.24Å; P508-F512 PolarHBondContact O-N 3.11Å; A509-F512 PolarHBondContact O-N 3.21Å; L510-F512 VanDerWaalsContact C-N 3.33Å; L510-F512 PolarHBondContact O-N 3.1Å; F512-N514 VanDerWaalsContact C-N 3.34Å; F512-N514 PolarHBondContact O-N 3.35Å; F512-N515 PolarHBondContact O-N 2.99Å; F512-N515 VanDerWaalsContact O-N 3.13Å; F512-L516 HydrophobicContact CD1-CD1 4.48Å; F512-L516 HydrophobicContact CE1-CD1 4.15Å; F512-L516 HydrophobicContact CE1-CD2 4.25Å; F512-L516 HydrophobicContact CE1-CG 4.34Å; F512-L516 HydrophobicContact CZ-CD2 4.22Å; F512-L516 PolarHBondContact O-N 2.89Å
513A85.2Confident80.2Confident1 Ų136.7 Ų36.71%0.00822%0.224CC..Hα-helixtrans-61.1-40179.700000112.8M175 C497 A509 L510 L516 A523M175-A513 HydrophobicContact SD-CB 4.38Å; C497-A513 HydrophobicContact CB-CB 3.68Å; A509-A513 WeakPolarHBondContact O-CB 3.42Å; A509-A513 PolarHBondContact O-N 3.12Å; L510-A513 PolarHBondContact O-N 3.29Å; A513-L516 WeakPolarHBondContact O-CB 3.49Å; A513-L516 PolarHBondContact O-N 3.21Å; A513-A523 HydrophobicContact CB-CB 3.76Å
514N74.4Confident79Confident53 Ų5338.6 Ų38.628%0.28324%0.239SC..Hα-helixtrans-68.2-36.2175.2-73.6-27.7000111.9L510 A511 F512 L516 H517 P518 A524L510-N514 WeakPolarHBondContact O-CB 3.49Å; L510-N514 PolarHBondContact O-N 2.99Å; L510-N514 PolarHBondContact O-ND2 2.96Å; A511-N514 PolarHBondContact O-N 3.45Å; F512-N514 VanDerWaalsContact C-N 3.34Å; F512-N514 PolarHBondContact O-N 3.35Å; N514-L516 PolarHBondContact O-N 2.91Å; N514-H517 CarbonylContact O-C 3.46Å; N514-H517 VanDerWaalsContact O-C 3.22Å; N514-H517 PolarHBondContact O-N 3.27Å; N514-P518 VanDerWaalsContact O-CA 3.29Å; N514-P518 WeakPolarHBondContact O-CA 3.39Å; N514-P518 VanDerWaalsContact O-N 3.17Å; N514-A524 PolarHBondContact OD1-N 3.17Å
515N83.6Confident78Confident125 Ų12542 Ų4267%0.66826%0.257SS*.Hα-helixtrans-69.2-16.9177.1-74.3-23.3000113.5A511 F512 H517A511-N515 WeakPolarHBondContact O-CB 3.36Å; A511-N515 VanDerWaalsContact O-CG 3.25Å; A511-N515 PolarHBondContact O-N 3.36Å; A511-N515 PolarHBondContact O-ND2 3.24Å; F512-N515 PolarHBondContact O-N 2.99Å; F512-N515 VanDerWaalsContact O-N 3.13Å; N515-H517 VanDerWaalsContact C-N 3.33Å
516L86.7Confident77.8Confident31 Ų3141.7 Ų41.716%0.16226%0.255CS..Hα-helixtrans-63.4-40.3172.1-66.9167.1000111.4V186 Y493 L494 F512 A513 N514V186-L516 HydrophobicContact CG1-CB 4.36Å; V186-L516 WeakPolarHBondContact CG1-O 3.34Å; Y493-L516 HydrophobicContact CE1-CD1 3.81Å; L494-L516 HydrophobicContact CD2-CB 4.04Å; F512-L516 HydrophobicContact CD1-CD1 4.48Å; F512-L516 HydrophobicContact CE1-CD1 4.15Å; F512-L516 HydrophobicContact CE1-CD2 4.25Å; F512-L516 HydrophobicContact CE1-CG 4.34Å; F512-L516 HydrophobicContact CZ-CD2 4.22Å; F512-L516 PolarHBondContact O-N 2.89Å; A513-L516 WeakPolarHBondContact O-CB 3.49Å; A513-L516 PolarHBondContact O-N 3.21Å; N514-L516 PolarHBondContact O-N 2.91Å
517H82.1Confident77.8Confident26 Ų2642.7 Ų42.712%0.1226%0.259CS..SBendtrans-154.990.5174.7-162.4-71.6000111.3V186 E187 A190 L494 N514 N515 T519 S520V186-H517 HydrophobicContact CG1-CB 3.95Å; E187-H517 IonicContact OE1-NE2 3.53Å; E187-H517 IonicContact OE2-CD2 3.36Å; E187-H517 IonicContact OE2-NE2 3.17Å; E187-H517 PolarHBondContact OE2-NE2 3.34Å; A190-H517 VanDerWaalsContact CB-CD2 3.41Å; A190-H517 WeakPolarHBondContact CB-CD2 3.31Å; A190-H517 VanDerWaalsContact CB-NE2 3.35Å; A190-H517 WeakPolarHBondContact CB-NE2 3.46Å; L494-H517 HydrophobicContact CD1-CB 3.99Å; L494-H517 HydrophobicContact CD2-CB 4.32Å; N514-H517 CarbonylContact O-C 3.46Å; N514-H517 VanDerWaalsContact O-C 3.22Å; N514-H517 PolarHBondContact O-N 3.27Å; N515-H517 VanDerWaalsContact C-N 3.33Å; H517-T519 PolarHBondContact CE1-OG1 2.8Å; H517-T519 PolarHBondContact ND1-OG1 3.42Å; H517-T519 PolarHBondContact O-N 2.86Å; H517-S520 PolarHBondContact ND1-N 2.91Å; H517-S520 PolarHBondContact O-N 3.33Å
518P70.5Confident77.6Confident104 Ų10441.9 Ų41.968%0.67526%0.259SS*.THydrogen-bonded Turntrans-58.3-29.1-167.3-27.734.9000115.4N514N514-P518 VanDerWaalsContact O-CA 3.29Å; N514-P518 WeakPolarHBondContact O-CA 3.39Å; N514-P518 VanDerWaalsContact O-N 3.17Å
519T65.9Low77.7Confident124 Ų12441.3 Ų41.376%0.76126%0.255SS*.THydrogen-bonded Turntrans-91.9-12.7-174.553.70000114.2H517 G521H517-T519 PolarHBondContact CE1-OG1 2.8Å; H517-T519 PolarHBondContact ND1-OG1 3.42Å; H517-T519 PolarHBondContact O-N 2.86Å; T519-G521 PolarHBondContact O-N 3.1Å
520S72.2Confident77.7Confident10 Ų1041.3 Ų41.37%0.0726%0.255CS..THydrogen-bonded Turntrans-70.7-36.8-173.9175.60000112.2R197 L494 H517 A522R197-S520 PolarHBondContact NH1-O 3.44Å; L494-S520 WeakPolarHBondContact CD1-OG 3.18Å; H517-S520 PolarHBondContact ND1-N 2.91Å; H517-S520 PolarHBondContact O-N 3.33Å; S520-A522 PolarHBondContact O-N 2.97Å; S520-A522 WeakPolarHBondContact OG-CB 3.5Å
521G69.4Low77.8Confident28 Ų2841.4 Ų41.429%0.28925%0.253SS..  trans67.2-2.7-175.900000115.3T519 A523 A524 L525T519-G521 PolarHBondContact O-N 3.1Å; G521-A523 PolarHBondContact O-N 3.11Å; G521-A524 PolarHBondContact O-N 3.16Å; G521-L525 WeakPolarHBondContact O-CB 3.41Å; G521-L525 PolarHBondContact O-N 3.19Å
522A75.2Confident78.1Confident1 Ų139.4 Ų39.41%0.00824%0.237CC..Hα-helixtrans-58.5-45.8-178.200000113.1H193 L494 S520 L525 S526H193-A522 VanDerWaalsContact CD2-CB 3.48Å; H193-A522 WeakPolarHBondContact CD2-CB 3.28Å; H193-A522 VanDerWaalsContact CE1-CB 3.48Å; H193-A522 WeakPolarHBondContact CE1-CB 3.49Å; H193-A522 WeakPolarHBondContact NE2-CB 3.22Å; L494-A522 HydrophobicContact CB-CB 3.68Å; S520-A522 PolarHBondContact O-N 2.97Å; S520-A522 WeakPolarHBondContact OG-CB 3.5Å; A522-L525 PolarHBondContact O-N 2.85Å; A522-S526 WeakPolarHBondContact O-CB 3.26Å; A522-S526 PolarHBondContact O-N 2.84Å; A522-S526 PolarHBondContact O-OG 3.28Å
523A80.4Confident78.2Confident4 Ų437.4 Ų37.43%0.03323%0.229CC..Hα-helixtrans-64.8-50-17900000111.3L494 G498 L510 A513 G521 L525 S526 Y527L494-A523 WeakPolarHBondContact O-CA 3.29Å; G498-A523 VanDerWaalsContact CA-O 3.29Å; G498-A523 WeakPolarHBondContact CA-O 3.37Å; L510-A523 HydrophobicContact CD1-CB 4.44Å; A513-A523 HydrophobicContact CB-CB 3.76Å; G521-A523 PolarHBondContact O-N 3.11Å; A523-L525 VanDerWaalsContact C-N 3.35Å; A523-L525 PolarHBondContact O-N 3.26Å; A523-S526 PolarHBondContact O-N 2.84Å; A523-Y527 VanDerWaalsContact O-CB 3.31Å; A523-Y527 WeakPolarHBondContact O-CB 3.4Å; A523-Y527 PolarHBondContact O-N 2.91Å
524A69.6Low78.5Confident40 Ų4037.4 Ų37.433%0.33123%0.228SC..Hα-helixtrans-56.7-44.7175.700000112.9N514 G521 A528N514-A524 PolarHBondContact OD1-N 3.17Å; G521-A524 PolarHBondContact O-N 3.16Å; A524-A528 WeakPolarHBondContact O-CB 3.46Å; A524-A528 PolarHBondContact O-N 2.87Å
525L73.3Confident79.1Confident73 Ų7335.1 Ų35.138%0.38222%0.216SC..Hα-helixtrans-64-45.1178.2-179.862.4000111.9G521 A522 A523 A528 T529G521-L525 WeakPolarHBondContact O-CB 3.41Å; G521-L525 PolarHBondContact O-N 3.19Å; A522-L525 PolarHBondContact O-N 2.85Å; A523-L525 VanDerWaalsContact C-N 3.35Å; A523-L525 PolarHBondContact O-N 3.26Å; L525-A528 PolarHBondContact O-N 3.17Å; L525-T529 WeakPolarHBondContact O-CB 2.68Å; L525-T529 PolarHBondContact O-N 2.96Å; L525-T529 PolarHBondContact O-OG1 2.76Å
526S82.3Confident79.1Confident3 Ų331.6 Ų31.62%0.02120%0.195CC..Hα-helixtrans-67.6-41-178.2-52.90000111.3T495 A522 A523 T529 V530T495-S526 WeakPolarHBondContact CA-OG 3.41Å; T495-S526 WeakPolarHBondContact CG2-OG 3.39Å; T495-S526 VanDerWaalsContact O-CB 3.25Å; T495-S526 WeakPolarHBondContact O-CB 3.49Å; T495-S526 PolarHBondContact O-OG 2.89Å; A522-S526 WeakPolarHBondContact O-CB 3.26Å; A522-S526 PolarHBondContact O-N 2.84Å; A522-S526 PolarHBondContact O-OG 3.28Å; A523-S526 PolarHBondContact O-N 2.84Å; S526-T529 WeakPolarHBondContact O-CB 3.26Å; S526-T529 PolarHBondContact O-N 3.26Å; S526-V530 PolarHBondContact O-N 3.08Å; S526-V530 VanDerWaalsContact O-N 3.14Å
527Y84.2Confident79.3Confident24 Ų2432.4 Ų32.49%0.09420%0.199CC..Hα-helixtrans-57.3-53.3172.2180-81.3000111G498 A501 L510 A523 T529 V530 Y531G498-Y527 WeakPolarHBondContact O-CA 3.34Å; A501-Y527 HydrophobicContact CB-CD2 3.85Å; A501-Y527 HydrophobicContact CB-CE2 4.27Å; L510-Y527 HydrophobicContact CB-CD2 3.84Å; L510-Y527 HydrophobicContact CB-CE2 3.96Å; L510-Y527 HydrophobicContact CB-CG 4.48Å; L510-Y527 HydrophobicContact CD1-CD2 3.98Å; L510-Y527 HydrophobicContact CD1-CG 3.92Å; L510-Y527 HydrophobicContact CD2-CD1 3.7Å; L510-Y527 HydrophobicContact CD2-CD2 3.77Å; L510-Y527 HydrophobicContact CD2-CE1 3.95Å; L510-Y527 HydrophobicContact CD2-CE2 3.99Å; L510-Y527 HydrophobicContact CD2-CG 3.62Å; L510-Y527 HydrophobicContact CG-CD2 4.06Å; L510-Y527 HydrophobicContact CG-CE2 4.47Å; L510-Y527 HydrophobicContact CG-CG 4.2Å; A523-Y527 VanDerWaalsContact O-CB 3.31Å; A523-Y527 WeakPolarHBondContact O-CB 3.4Å; A523-Y527 PolarHBondContact O-N 2.91Å; Y527-T529 PolarHBondContact O-N 3.5Å; Y527-V530 PolarHBondContact O-N 3.23Å; Y527-Y531 HydrophobicContact CD1-CG 4.44Å; Y527-Y531 HydrophobicContact CE1-CD1 4.44Å; Y527-Y531 AromaticContact CE1-CD2 3.64Å; Y527-Y531 HydrophobicContact CE1-CD2 3.64Å; Y527-Y531 HydrophobicContact CE1-CE2 4.15Å; Y527-Y531 AromaticContact CE1-CG 3.77Å; Y527-Y531 HydrophobicContact CE1-CG 3.77Å; Y527-Y531 HydrophobicContact CE2-CD2 4.13Å; Y527-Y531 AromaticContact CZ-CD2 3.39Å; Y527-Y531 AromaticContact CZ-CE2 3.72Å; Y527-Y531 WeakPolarHBondContact O-CB 3.05Å; Y527-Y531 PolarHBondContact O-N 2.88Å; Y527-Y531 WeakPolarHBondContact OH-CD2 3.26Å; Y527-Y531 WeakPolarHBondContact OH-CE2 3.19Å
528A71.3Confident79.8Confident59 Ų5931.2 Ų31.249%0.48819%0.194SC..Hα-helixtrans-61-29.3-179.800000112.7A524 L525 P532A524-A528 WeakPolarHBondContact O-CB 3.46Å; A524-A528 PolarHBondContact O-N 2.87Å; L525-A528 PolarHBondContact O-N 3.17Å; A528-P532 VanDerWaalsContact O-CD 3.27Å; A528-P532 WeakPolarHBondContact O-CD 3.48Å
529T77.6Confident80.6Confident23 Ų2326.3 Ų26.314%0.14116%0.162CC..Hα-helixtrans-70.2-47.1177.7-57.80000111.7S85 L93 L525 S526 Y527S85-T529 WeakPolarHBondContact CB-O 3.34Å; L93-T529 HydrophobicContact CB-CG2 4.33Å; L93-T529 HydrophobicContact CD1-CG2 4.06Å; L525-T529 WeakPolarHBondContact O-CB 2.68Å; L525-T529 PolarHBondContact O-N 2.96Å; L525-T529 PolarHBondContact O-OG1 2.76Å; S526-T529 WeakPolarHBondContact O-CB 3.26Å; S526-T529 PolarHBondContact O-N 3.26Å; Y527-T529 PolarHBondContact O-N 3.5Å
530V87.3Confident81.6Confident0 Ų022.3 Ų22.30%014%0.135CC..Hα-helixtrans-91.9-27.3-172.3-55.40000114.1L93 N94 A97 M499 S526 Y527 L533 V534L93-V530 HydrophobicContact CB-CG1 3.66Å; N94-V530 WeakPolarHBondContact OD1-CA 3.48Å; A97-V530 HydrophobicContact CB-CB 3.67Å; A97-V530 HydrophobicContact CB-CG1 3.82Å; A97-V530 HydrophobicContact CB-CG2 4.24Å; M499-V530 HydrophobicContact CG-CG1 4.14Å; S526-V530 PolarHBondContact O-N 3.08Å; S526-V530 VanDerWaalsContact O-N 3.14Å; Y527-V530 PolarHBondContact O-N 3.23Å; V530-L533 PolarHBondContact O-N 2.69Å; V530-V534 HydrophobicContact CB-CG2 4.3Å; V530-V534 WeakPolarHBondContact O-CB 3.42Å; V530-V534 VanDerWaalsContact O-CG2 3.28Å; V530-V534 WeakPolarHBondContact O-CG2 3.38Å; V530-V534 PolarHBondContact O-N 2.87Å
531Y83.9Confident82.5Confident30 Ų3022.7 Ų22.712%0.11814%0.137CC..Hα-helixtrans-54.6-46.5-172.6177.7-94.1000113.7V78 T505 Y527 L533 M535V78-Y531 HydrophobicContact CG1-CD1 3.73Å; V78-Y531 HydrophobicContact CG1-CE1 3.72Å; T505-Y531 HydrophobicContact CG2-CD2 4.05Å; T505-Y531 HydrophobicContact CG2-CE2 3.87Å; Y527-Y531 HydrophobicContact CD1-CG 4.44Å; Y527-Y531 HydrophobicContact CE1-CD1 4.44Å; Y527-Y531 AromaticContact CE1-CD2 3.64Å; Y527-Y531 HydrophobicContact CE1-CD2 3.64Å; Y527-Y531 HydrophobicContact CE1-CE2 4.15Å; Y527-Y531 AromaticContact CE1-CG 3.77Å; Y527-Y531 HydrophobicContact CE1-CG 3.77Å; Y527-Y531 HydrophobicContact CE2-CD2 4.13Å; Y527-Y531 AromaticContact CZ-CD2 3.39Å; Y527-Y531 AromaticContact CZ-CE2 3.72Å; Y527-Y531 WeakPolarHBondContact O-CB 3.05Å; Y527-Y531 PolarHBondContact O-N 2.88Å; Y527-Y531 WeakPolarHBondContact OH-CD2 3.26Å; Y527-Y531 WeakPolarHBondContact OH-CE2 3.19Å; Y531-L533 PolarHBondContact O-N 2.76Å; Y531-M535 HydrophobicContact CD1-SD 4.43Å; Y531-M535 HydrophobicContact CE1-CE 3.87Å; Y531-M535 HydrophobicContact CE1-SD 3.64Å; Y531-M535 HydrophobicContact CE2-CE 3.79Å; Y531-M535 WeakPolarHBondContact O-CB 3.45Å; Y531-M535 PolarHBondContact O-N 3.02Å; Y531-M535 WeakPolarHBondContact OH-CE 3.48Å
532P80.7Confident83.5Confident6 Ų621.4 Ų21.44%0.03912%0.124CC..Hα-helixtrans-57.8-47.8179-27.337000114V78 F82 A528 F536V78-P532 HydrophobicContact CB-CB 4Å; V78-P532 HydrophobicContact CB-CG 4.15Å; V78-P532 HydrophobicContact CG1-CB 4.29Å; V78-P532 HydrophobicContact CG1-CG 4.09Å; F82-P532 HydrophobicContact CB-CB 3.82Å; F82-P532 HydrophobicContact CD2-CB 3.88Å; F82-P532 WeakPolarHBondContact CD2-O 3.27Å; F82-P532 HydrophobicContact CG-CB 4.32Å; A528-P532 VanDerWaalsContact O-CD 3.27Å; A528-P532 WeakPolarHBondContact O-CD 3.48Å; P532-F536 PolarHBondContact O-N 2.78Å
533L86.1Confident84.1Confident21 Ų2122.4 Ų22.411%0.1113%0.128CC..Hα-helixtrans-69.1-47.7-176.1177.962.1000111F82 L86 N94 V98 V530 Y531 M535 F536 L537F82-L533 HydrophobicContact CE2-CB 4.47Å; F82-L533 HydrophobicContact CE2-CD1 4.04Å; F82-L533 HydrophobicContact CZ-CD1 4.1Å; L86-L533 HydrophobicContact CD2-CD1 4.34Å; L86-L533 HydrophobicContact CD2-CD2 4.17Å; N94-L533 HydrophobicContact CB-CD2 3.79Å; V98-L533 HydrophobicContact CG2-CD2 3.69Å; V98-L533 HydrophobicContact CG2-CG 4.33Å; V530-L533 PolarHBondContact O-N 2.69Å; Y531-L533 PolarHBondContact O-N 2.76Å; L533-M535 VanDerWaalsContact C-N 3.34Å; L533-M535 PolarHBondContact O-N 2.85Å; L533-F536 PolarHBondContact O-N 2.91Å; L533-L537 HydrophobicContact CD1-CD1 4.2Å; L533-L537 HydrophobicContact CD1-CG 4.39Å; L533-L537 HydrophobicContact CG-CD1 4.04Å; L533-L537 WeakPolarHBondContact O-CG 3.4Å; L533-L537 PolarHBondContact O-N 3.46Å
534V91.5Very high84.5Confident0 Ų027.3 Ų27.30%015%0.154CC..Hα-helixtrans-61.3-45.6179.2170.30000110.7A97 V101 S503 T505 V530 F536 L537 R538A97-V534 HydrophobicContact CB-CG2 3.51Å; V101-V534 HydrophobicContact CG2-CB 4.49Å; V101-V534 HydrophobicContact CG2-CG1 3.86Å; V101-V534 HydrophobicContact CG2-CG2 4.47Å; S503-V534 WeakPolarHBondContact O-CG1 3.34Å; T505-V534 HydrophobicContact CG2-CG1 4.46Å; V530-V534 HydrophobicContact CB-CG2 4.3Å; V530-V534 WeakPolarHBondContact O-CB 3.42Å; V530-V534 VanDerWaalsContact O-CG2 3.28Å; V530-V534 WeakPolarHBondContact O-CG2 3.38Å; V530-V534 PolarHBondContact O-N 2.87Å; V534-F536 VanDerWaalsContact C-N 3.28Å; V534-F536 PolarHBondContact O-N 3.2Å; V534-L537 PolarHBondContact O-N 2.83Å; V534-L537 VanDerWaalsContact O-N 3.15Å; V534-R538 HydrophobicContact CG1-CG 4.04Å; V534-R538 WeakPolarHBondContact O-CB 3.33Å; V534-R538 WeakPolarHBondContact O-CG 2.81Å; V534-R538 PolarHBondContact O-N 3.01Å
535M86.4Confident85.5Confident6 Ų626.4 Ų26.43%0.0314%0.143CC..Hα-helixtrans-57-45.5-179.3173.2161.5-94.800111.4I74 T505 Y531 L533 R538 I539I74-M535 HydrophobicContact CB-SD 4.35Å; I74-M535 HydrophobicContact CD1-CE 3.87Å; I74-M535 HydrophobicContact CD1-SD 4.19Å; I74-M535 HydrophobicContact CG1-CE 4.5Å; I74-M535 HydrophobicContact CG1-SD 4.37Å; I74-M535 HydrophobicContact CG2-CE 4.23Å; I74-M535 HydrophobicContact CG2-CG 4.23Å; I74-M535 HydrophobicContact CG2-SD 3.14Å; I74-M535 WeakPolarHBondContact CG2-SD 3.23Å; T505-M535 HydrophobicContact CG2-CB 4.2Å; T505-M535 HydrophobicContact CG2-CE 4.11Å; Y531-M535 HydrophobicContact CD1-SD 4.43Å; Y531-M535 HydrophobicContact CE1-CE 3.87Å; Y531-M535 HydrophobicContact CE1-SD 3.64Å; Y531-M535 HydrophobicContact CE2-CE 3.79Å; Y531-M535 WeakPolarHBondContact O-CB 3.45Å; Y531-M535 PolarHBondContact O-N 3.02Å; Y531-M535 WeakPolarHBondContact OH-CE 3.48Å; L533-M535 VanDerWaalsContact C-N 3.34Å; L533-M535 PolarHBondContact O-N 2.85Å; M535-R538 PolarHBondContact O-N 3.41Å; M535-I539 HydrophobicContact CG-CD1 4.09Å; M535-I539 WeakPolarHBondContact O-CD1 3.41Å; M535-I539 VanDerWaalsContact O-CG1 3.27Å; M535-I539 WeakPolarHBondContact O-CG1 3.4Å; M535-I539 PolarHBondContact O-N 2.91Å; M535-I539 VanDerWaalsContact O-N 3.12Å
536F85Confident86.3Confident50 Ų5022.9 Ų22.922%0.21913%0.125CC..Hα-helixtrans-59.4-51173.5175.1-100.9000112F82 L407 I408 L411 P532 L533 V534 R538 I539 I540F82-F536 HydrophobicContact CE2-CB 3.8Å; F82-F536 HydrophobicContact CE2-CD1 4.34Å; F82-F536 HydrophobicContact CE2-CG 4.1Å; F82-F536 HydrophobicContact CZ-CD1 4.35Å; F82-F536 HydrophobicContact CZ-CG 4.43Å; L407-F536 HydrophobicContact CD2-CD2 4.11Å; I408-F536 HydrophobicContact CD1-CE2 4.31Å; I408-F536 HydrophobicContact CG1-CE2 4Å; L411-F536 HydrophobicContact CD1-CD2 4.15Å; P532-F536 PolarHBondContact O-N 2.78Å; L533-F536 PolarHBondContact O-N 2.91Å; V534-F536 VanDerWaalsContact C-N 3.28Å; V534-F536 PolarHBondContact O-N 3.2Å; F536-R538 VanDerWaalsContact C-N 3.33Å; F536-R538 PolarHBondContact O-N 3.11Å; F536-I539 PolarHBondContact O-N 2.93Å; F536-I540 HydrophobicContact CD1-CD1 4Å; F536-I540 HydrophobicContact CD2-CD1 4.12Å; F536-I540 HydrophobicContact CE1-CD1 3.41Å; F536-I540 VanDerWaalsContact CE1-CD1 3.41Å; F536-I540 HydrophobicContact CE2-CD1 3.54Å; F536-I540 HydrophobicContact CG-CD1 4.34Å; F536-I540 HydrophobicContact CZ-CD1 3.16Å; F536-I540 PolarHBondContact O-N 2.76Å
537L91.2Very high86.4Confident49 Ų4923.2 Ų23.226%0.25713%0.126SC..Hα-helixtrans-62.2-39.2-178.9-67.5172.5000112.5V98 V101 L533 V534 I539 I540 T541V98-L537 HydrophobicContact CB-CD1 4.45Å; V98-L537 HydrophobicContact CG1-CD1 4.44Å; V98-L537 HydrophobicContact CG2-CD1 3.7Å; V101-L537 HydrophobicContact CG1-CB 4.02Å; L533-L537 HydrophobicContact CD1-CD1 4.2Å; L533-L537 HydrophobicContact CD1-CG 4.39Å; L533-L537 HydrophobicContact CG-CD1 4.04Å; L533-L537 WeakPolarHBondContact O-CG 3.4Å; L533-L537 PolarHBondContact O-N 3.46Å; V534-L537 PolarHBondContact O-N 2.83Å; V534-L537 VanDerWaalsContact O-N 3.15Å; L537-I539 VanDerWaalsContact C-N 3.35Å; L537-I540 PolarHBondContact O-N 2.99Å; L537-T541 WeakPolarHBondContact O-CB 3.43Å; L537-T541 PolarHBondContact O-N 3.29Å; L537-T541 PolarHBondContact O-OG1 2.85Å
538R91.9Very high86.4Confident0 Ų026.2 Ų26.20%014%0.143CC..Hα-helixtrans-69-30.8178.2-76.8-165177.4-76.91.6113.3V101 V130 N132 A135 S503 M504 V534 M535 F536 I540 P542V101-R538 HydrophobicContact CG1-CG 4.31Å; V101-R538 HydrophobicContact CG2-CG 4.01Å; V130-R538 VanDerWaalsContact CB-CZ 3.46Å; N132-R538 VanDerWaalsContact ND2-CB 3.34Å; N132-R538 WeakPolarHBondContact ND2-CB 3.35Å; A135-R538 VanDerWaalsContact CB-O 3.29Å; A135-R538 WeakPolarHBondContact CB-O 3.19Å; S503-R538 VanDerWaalsContact O-CZ 3.23Å; S503-R538 PolarHBondContact O-NE 3.37Å; S503-R538 PolarHBondContact O-NH2 3.16Å; M504-R538 PolarHBondContact SD-NH2 3.18Å; V534-R538 HydrophobicContact CG1-CG 4.04Å; V534-R538 WeakPolarHBondContact O-CB 3.33Å; V534-R538 WeakPolarHBondContact O-CG 2.81Å; V534-R538 PolarHBondContact O-N 3.01Å; M535-R538 PolarHBondContact O-N 3.41Å; F536-R538 VanDerWaalsContact C-N 3.33Å; F536-R538 PolarHBondContact O-N 3.11Å; R538-I540 VanDerWaalsContact C-N 3.35Å; R538-P542 WeakPolarHBondContact O-CD 3.37Å
539I87.4Confident87.1Confident1 Ų124 Ų241%0.00512%0.123CC..Hα-helixtrans-69.2-38.2174.3-73166.5000110.9P134 A138 L407 M535 F536 L537P134-I539 HydrophobicContact CB-CD1 3.43Å; P134-I539 VanDerWaalsContact CB-CD1 3.43Å; P134-I539 HydrophobicContact CB-CG1 3.48Å; P134-I539 VanDerWaalsContact CB-CG1 3.48Å; P134-I539 HydrophobicContact CG-CD1 4.26Å; A138-I539 HydrophobicContact CB-CG2 3.94Å; L407-I539 HydrophobicContact CD1-CD1 4.4Å; L407-I539 HydrophobicContact CD2-CB 4.4Å; L407-I539 HydrophobicContact CD2-CD1 3.47Å; L407-I539 VanDerWaalsContact CD2-CD1 3.47Å; L407-I539 HydrophobicContact CD2-CG2 4.28Å; M535-I539 HydrophobicContact CG-CD1 4.09Å; M535-I539 WeakPolarHBondContact O-CD1 3.41Å; M535-I539 VanDerWaalsContact O-CG1 3.27Å; M535-I539 WeakPolarHBondContact O-CG1 3.4Å; M535-I539 PolarHBondContact O-N 2.91Å; M535-I539 VanDerWaalsContact O-N 3.12Å; F536-I539 PolarHBondContact O-N 2.93Å; L537-I539 VanDerWaalsContact C-N 3.35Å
540I86.4Confident87.1Confident40 Ų4027.4 Ų27.421%0.20513%0.133CC..Hα-helixtrans-77-31.4-180-69175.6000112F536 L537 R538 Q543 L544F536-I540 HydrophobicContact CD1-CD1 4Å; F536-I540 HydrophobicContact CD2-CD1 4.12Å; F536-I540 HydrophobicContact CE1-CD1 3.41Å; F536-I540 VanDerWaalsContact CE1-CD1 3.41Å; F536-I540 HydrophobicContact CE2-CD1 3.54Å; F536-I540 HydrophobicContact CG-CD1 4.34Å; F536-I540 HydrophobicContact CZ-CD1 3.16Å; F536-I540 PolarHBondContact O-N 2.76Å; L537-I540 PolarHBondContact O-N 2.99Å; R538-I540 VanDerWaalsContact C-N 3.35Å; I540-Q543 WeakPolarHBondContact O-CA 3.42Å; I540-Q543 WeakPolarHBondContact O-CB 3.48Å; I540-Q543 PolarHBondContact O-N 3.25Å; I540-L544 HydrophobicContact CG2-CD1 3.63Å; I540-L544 HydrophobicContact CG2-CD2 4.4Å; I540-L544 HydrophobicContact CG2-CG 3.7Å; I540-L544 PolarHBondContact O-N 3.31Å
541T91.5Very high86.2Confident19 Ų1930.1 Ų30.112%0.11715%0.152CC..Hα-helixtrans-56.2-49.1-173.6-61.50000113.4F126 L537 Q543 L544 L545F126-T541 HydrophobicContact CE1-CG2 3.98Å; F126-T541 HydrophobicContact CE2-CG2 4.22Å; F126-T541 HydrophobicContact CZ-CG2 3.57Å; L537-T541 WeakPolarHBondContact O-CB 3.43Å; L537-T541 PolarHBondContact O-N 3.29Å; L537-T541 PolarHBondContact O-OG1 2.85Å; T541-Q543 VanDerWaalsContact C-N 3.26Å; T541-Q543 PolarHBondContact O-N 3.09Å; T541-L544 PolarHBondContact O-N 3.12Å; T541-L545 HydrophobicContact CG2-CD1 3.9Å; T541-L545 HydrophobicContact CG2-CG 4.19Å; T541-L545 WeakPolarHBondContact O-CG 3.46Å; T541-L545 PolarHBondContact O-N 2.88Å
542P90.1Very high85.3Confident0 Ų033.4 Ų33.40%017%0.17CC..Hα-helixtrans-60.3-35.3175.9-20.628.3000113.1L123 F126 A135 R538 L545 A546L123-P542 HydrophobicContact CD2-CB 4.17Å; F126-P542 HydrophobicContact CD1-CG 3.98Å; F126-P542 HydrophobicContact CE1-CG 3.84Å; A135-P542 HydrophobicContact CB-CG 3.79Å; R538-P542 WeakPolarHBondContact O-CD 3.37Å; P542-L545 PolarHBondContact O-N 3.21Å; P542-A546 WeakPolarHBondContact O-CB 3.48Å; P542-A546 PolarHBondContact O-N 3.28Å
543Q87.8Confident84.1Confident22 Ų2238.8 Ų38.810%0.10323%0.227CC..Hα-helixtrans-64.7-47.7176.5-58.1-178.8-6.300110.8A138 I142 L400 I540 T541 L545 A546 V547A138-Q543 HydrophobicContact CB-CG 4.34Å; I142-Q543 HydrophobicContact CB-CG 4.27Å; I142-Q543 HydrophobicContact CG2-CG 4.27Å; L400-Q543 PolarHBondContact O-NE2 3.32Å; I540-Q543 WeakPolarHBondContact O-CA 3.42Å; I540-Q543 WeakPolarHBondContact O-CB 3.48Å; I540-Q543 PolarHBondContact O-N 3.25Å; T541-Q543 VanDerWaalsContact C-N 3.26Å; T541-Q543 PolarHBondContact O-N 3.09Å; Q543-L545 PolarHBondContact O-N 3.03Å; Q543-A546 PolarHBondContact O-N 3.02Å; Q543-V547 VanDerWaalsContact O-CB 3.23Å; Q543-V547 WeakPolarHBondContact O-CB 3.39Å; Q543-V547 WeakPolarHBondContact O-CG2 3.45Å; Q543-V547 PolarHBondContact O-N 3.24Å
544L88Confident84Confident108 Ų10839.7 Ų39.757%0.56523%0.233SC*.Hα-helixtrans-62-44.1176.4-66.5177.8000112.1I540 T541 L548I540-L544 HydrophobicContact CG2-CD1 3.63Å; I540-L544 HydrophobicContact CG2-CD2 4.4Å; I540-L544 HydrophobicContact CG2-CG 3.7Å; I540-L544 PolarHBondContact O-N 3.31Å; T541-L544 PolarHBondContact O-N 3.12Å; L544-L548 WeakPolarHBondContact O-CB 3.27Å; L544-L548 PolarHBondContact O-N 3.32Å
545L91.5Very high83.7Confident20 Ų2041.7 Ų41.711%0.10525%0.245CC..Hα-helixtrans-64.7-44.7177.9-69.2177000111.6T108 L123 T541 P542 Q543 V547 L548 F549T108-L545 HydrophobicContact CG2-CD1 3.98Å; L123-L545 HydrophobicContact CD2-CB 3.7Å; L123-L545 HydrophobicContact CD2-CD1 4.25Å; T541-L545 HydrophobicContact CG2-CD1 3.9Å; T541-L545 HydrophobicContact CG2-CG 4.19Å; T541-L545 WeakPolarHBondContact O-CG 3.46Å; T541-L545 PolarHBondContact O-N 2.88Å; P542-L545 PolarHBondContact O-N 3.21Å; Q543-L545 PolarHBondContact O-N 3.03Å; L545-V547 VanDerWaalsContact C-N 3.33Å; L545-V547 PolarHBondContact O-N 3.24Å; L545-L548 PolarHBondContact O-N 3.35Å; L545-F549 HydrophobicContact CB-CD2 4.31Å; L545-F549 HydrophobicContact CB-CE2 4.09Å; L545-F549 HydrophobicContact CD2-CE2 3.82Å; L545-F549 HydrophobicContact CD2-CZ 4.12Å; L545-F549 HydrophobicContact CG-CE2 4.47Å; L545-F549 WeakPolarHBondContact O-CB 3.47Å; L545-F549 WeakPolarHBondContact O-CD2 3.38Å; L545-F549 WeakPolarHBondContact O-CG 3.46Å; L545-F549 PolarHBondContact O-N 3.38Å
546A89.6Confident83.5Confident0 Ų043.7 Ų43.70%026%0.257CS..Hα-helixtrans-56.4-50.8177.100000110.9L123 I142 L143 L146 P542 Q543 F549 W550L123-A546 HydrophobicContact CD1-CB 3.74Å; I142-A546 HydrophobicContact CG1-CB 4.3Å; I142-A546 HydrophobicContact CG2-CB 3.73Å; L143-A546 HydrophobicContact CD2-CB 4.46Å; L146-A546 HydrophobicContact CD1-CB 4.27Å; P542-A546 WeakPolarHBondContact O-CB 3.48Å; P542-A546 PolarHBondContact O-N 3.28Å; Q543-A546 PolarHBondContact O-N 3.02Å; A546-F549 PolarHBondContact O-N 2.94Å; A546-W550 WeakPolarHBondContact O-CB 3.49Å; A546-W550 PolarHBondContact O-N 2.91Å
547V84.4Confident83.4Confident9 Ų943.4 Ų43.46%0.05526%0.259CS..Hα-helixtrans-64.8-44.8-177.4166.60000111.2I142 F394 L398 Q543 L545 S551I142-V547 HydrophobicContact CD1-CG2 4.03Å; I142-V547 HydrophobicContact CG1-CG2 3.94Å; F394-V547 HydrophobicContact CD1-CG1 3.26Å; F394-V547 HydrophobicContact CD2-CG1 4.24Å; F394-V547 HydrophobicContact CE1-CB 4.21Å; F394-V547 HydrophobicContact CE1-CG1 2.99Å; F394-V547 WeakPolarHBondContact CE1-O 3.48Å; F394-V547 HydrophobicContact CE2-CG1 3.97Å; F394-V547 HydrophobicContact CG-CG1 3.9Å; F394-V547 HydrophobicContact CZ-CG1 3.35Å; L398-V547 HydrophobicContact CD1-CG1 4.01Å; L398-V547 HydrophobicContact CD1-CG2 4.43Å; L398-V547 HydrophobicContact CD2-CB 4.34Å; L398-V547 HydrophobicContact CD2-CG1 3.96Å; L398-V547 HydrophobicContact CD2-CG2 3.35Å; Q543-V547 VanDerWaalsContact O-CB 3.23Å; Q543-V547 WeakPolarHBondContact O-CB 3.39Å; Q543-V547 WeakPolarHBondContact O-CG2 3.45Å; Q543-V547 PolarHBondContact O-N 3.24Å; L545-V547 VanDerWaalsContact C-N 3.33Å; L545-V547 PolarHBondContact O-N 3.24Å; V547-S551 PolarHBondContact O-N 3.16Å
548L85.1Confident82.9Confident87 Ų8743 Ų4346%0.45526%0.26SS..Hα-helixtrans-67.4-37.9-179.9-169.3141000112.6L544 L545 S551 I552L544-L548 WeakPolarHBondContact O-CB 3.27Å; L544-L548 PolarHBondContact O-N 3.32Å; L545-L548 PolarHBondContact O-N 3.35Å; L548-S551 PolarHBondContact O-OG 2.7Å; L548-I552 HydrophobicContact CD2-CD1 3.74Å; L548-I552 HydrophobicContact CG-CD1 4.29Å; L548-I552 WeakPolarHBondContact O-CD1 3.09Å; L548-I552 WeakPolarHBondContact O-CG1 3.05Å
549F85.8Confident82.3Confident13 Ų1345.9 Ų45.96%0.05728%0.277CS..Hα-helixtrans-82.6-30.8177.8-62.6-43.9000113.2A109 H112 L119 L545 A546 S551 I552 G553A109-F549 HydrophobicContact CB-CE1 4.46Å; A109-F549 HydrophobicContact CB-CE2 4.36Å; A109-F549 HydrophobicContact CB-CZ 3.56Å; H112-F549 HydrophobicContact CB-CE2 4.47Å; H112-F549 AromaticContact CD2-CD1 3.68Å; H112-F549 AromaticContact CD2-CD2 3.48Å; H112-F549 VanDerWaalsContact CD2-CD2 3.48Å; H112-F549 WeakPolarHBondContact CD2-CD2 3.32Å; H112-F549 AromaticContact CD2-CE1 3.95Å; H112-F549 AromaticContact CD2-CE2 3.73Å; H112-F549 AromaticContact CD2-CG 3.48Å; H112-F549 VanDerWaalsContact CD2-CG 3.48Å; H112-F549 WeakPolarHBondContact CD2-CG 3.38Å; H112-F549 AromaticContact CD2-CZ 3.98Å; H112-F549 AromaticContact NE2-CD2 3.92Å; H112-F549 AromaticContact NE2-CG 3.62Å; L119-F549 HydrophobicContact CD1-CB 3.86Å; L119-F549 HydrophobicContact CD1-CD2 3.8Å; L119-F549 HydrophobicContact CD1-CG 4.32Å; L545-F549 HydrophobicContact CB-CD2 4.31Å; L545-F549 HydrophobicContact CB-CE2 4.09Å; L545-F549 HydrophobicContact CD2-CE2 3.82Å; L545-F549 HydrophobicContact CD2-CZ 4.12Å; L545-F549 HydrophobicContact CG-CE2 4.47Å; L545-F549 WeakPolarHBondContact O-CB 3.47Å; L545-F549 WeakPolarHBondContact O-CD2 3.38Å; L545-F549 WeakPolarHBondContact O-CG 3.46Å; L545-F549 PolarHBondContact O-N 3.38Å; A546-F549 PolarHBondContact O-N 2.94Å; F549-S551 VanDerWaalsContact C-N 3.26Å; F549-S551 PolarHBondContact O-N 3.47Å; F549-I552 PolarHBondContact O-N 3.25Å; F549-I552 VanDerWaalsContact O-N 3.16Å; F549-G553 PolarHBondContact O-N 2.75Å
550W77.2Confident82Confident95 Ų9549.1 Ų49.136%0.3630%0.296SS..Hα-helixtrans-64.6-30.2173.4-170.7-86.9000112.8L119 L146 T148 A546 I552L119-W550 HydrophobicContact CD2-CE3 4.23Å; L146-W550 HydrophobicContact CB-CD2 4.15Å; L146-W550 HydrophobicContact CB-CE3 4.46Å; L146-W550 HydrophobicContact CB-CZ2 4.44Å; L146-W550 HydrophobicContact CD1-CB 3.98Å; L146-W550 HydrophobicContact CD1-CD2 4.18Å; L146-W550 HydrophobicContact CD1-CE3 4.46Å; L146-W550 HydrophobicContact CD1-CG 3.96Å; L146-W550 HydrophobicContact CD2-CG 4.18Å; L146-W550 HydrophobicContact CG-CG 4.46Å; L146-W550 VanDerWaalsContact O-CZ2 3.28Å; L146-W550 WeakPolarHBondContact O-CZ2 3.14Å; T148-W550 WeakPolarHBondContact OG1-CZ3 3.28Å; A546-W550 WeakPolarHBondContact O-CB 3.49Å; A546-W550 PolarHBondContact O-N 2.91Å; W550-I552 VanDerWaalsContact C-N 3.32Å
551S68.9Low81.6Confident56 Ų5649.8 Ų49.839%0.39230%0.303SS..THydrogen-bonded Turntrans-81.5-12.6175.983.30000113.7V547 L548 F549V547-S551 PolarHBondContact O-N 3.16Å; L548-S551 PolarHBondContact O-OG 2.7Å; F549-S551 VanDerWaalsContact C-N 3.26Å; F549-S551 PolarHBondContact O-N 3.47Å
552I64.8Low80.8Confident99 Ų9952.3 Ų52.351%0.50832%0.319SS..THydrogen-bonded Turntrans-103.7-29.9-175-64.7170.1000111.4L548 F549 W550L548-I552 HydrophobicContact CD2-CD1 3.74Å; L548-I552 HydrophobicContact CG-CD1 4.29Å; L548-I552 WeakPolarHBondContact O-CD1 3.09Å; L548-I552 WeakPolarHBondContact O-CG1 3.05Å; F549-I552 PolarHBondContact O-N 3.25Å; F549-I552 VanDerWaalsContact O-N 3.16Å; W550-I552 VanDerWaalsContact C-N 3.32Å
553G56.6Low80Confident119 Ų11957.1 Ų57.1100%1.22735%0.348SS*.  trans-78.6016800000111.3F549F549-G553 PolarHBondContact O-N 2.75Å

Retrieved 553 of 553 residues in 307.2 ms (Link to these results)