A0A087X2I5_HUMAN Loading...

LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated

AlphaFold DB (A0A2J8IMA4), UniProt , Accession A0A087X2I5, Species HUMAN (Homo sapiens, Human), Gene LSM7, Length 49 aa.

						>A0A087X2I5_HUMAN|A0A087X2I5|LSM7
MRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFIQQQDA
					

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	85.3	Confident	91.4	Very high	125 Å²	125	115.6 Å²	115.6	62%	0.616	56%	0.56	S	S	*	*				0	174	0	-162.1	172.3	-165.4	0	0	107.6	T11 D13	M1-T11 PolarHBondContact N-O 3.11Å; M1-T11 WeakPolarHBondContact CA-OG1 3.31Å; M1-T11 PolarHBondContact O-OG1 3.14Å; M1-T11 PolarHBondContact O-N 3.1Å; M1-T11 PolarHBondContact N-OG1 3.25Å; M1-T11 WeakPolarHBondContact O-CA 3.48Å; M1-D13 HydrophobicContact CB-CB 3.99Å; M1-D13 PolarHBondContact N-O 2.74Å
2	R	90.9	Very high	91.4	Very high	167 Å²	167	122.3 Å²	122.3	63%	0.63	59%	0.59	S	S	*	*	B	Isolated β-bridge	trans	-87.3	144	169.2	-72.8	-177.3	-176.9	-166.3	5	109.2	Q7 L10	R2-Q7 WeakPolarHBondContact CD-O 3.35Å; R2-L10 HydrophobicContact CG-CD1 4.39Å
3	D	91.9	Very high	91.5	Very high	29 Å²	29	121 Å²	121	16%	0.155	59%	0.588	C	S	.	*			trans	-62.2	131.2	174.5	-168.7	-49.6	0	0	0	108.9	D5 D6 K9 T11	D3-D5 PolarHBondContact O-N 3.38Å; D3-D5 PolarHBondContact OD1-N 2.94Å; D3-D6 WeakPolarHBondContact CB-O 3.48Å; D3-D6 CarbonylContact O-C 3.4Å; D3-D6 PolarHBondContact O-N 2.81Å; D3-D6 PolarHBondContact OD1-N 2.83Å; D3-K9 IonicContact OD2-NZ 2.81Å; D3-K9 PolarHBondContact OD2-NZ 2.92Å; D3-K9 VanDerWaalsContact N-O 3.08Å; D3-K9 HydrophobicContact CB-CG 4.32Å; D3-K9 HydrophobicContact CB-CD 4.22Å; D3-K9 HydrophobicContact CB-CB 4.05Å; D3-K9 PolarHBondContact N-O 2.94Å; D3-T11 HydrophobicContact CB-CG2 4.13Å
4	P	92	Very high	91.6	Very high	124 Å²	124	121.9 Å²	121.9	81%	0.805	60%	0.604	S	S	*	*	S	Bend	trans	-65.5	-26.5	-179.2	26.4	-34.6	0	0	0	113.2
5	D	94.6	Very high	91.8	Very high	158 Å²	158	125.7 Å²	125.7	85%	0.845	61%	0.609	S	S	*	*	S	Bend	trans	-93.2	-19.9	-178.9	-62.1	-49.1	0	0	0	112.1	D3	D3-D5 PolarHBondContact O-N 3.38Å; D3-D5 PolarHBondContact OD1-N 2.94Å
6	D	93.4	Very high	92.1	Very high	73 Å²	73	129.3 Å²	129.3	39%	0.39	62%	0.624	S	S	.	*			trans	-140.3	105.3	176.5	-175.4	-3	0	0	0	113.1	D3 Y8 K9	D3-D6 WeakPolarHBondContact CB-O 3.48Å; D3-D6 CarbonylContact O-C 3.4Å; D3-D6 PolarHBondContact O-N 2.81Å; D3-D6 PolarHBondContact OD1-N 2.83Å; D6-Y8 PolarHBondContact O-N 3.49Å; D6-Y8 VanDerWaalsContact O-N 3.1Å; D6-Y8 PolarHBondContact OD1-N 3.45Å; D6-K9 VanDerWaalsContact O-N 3.12Å; D6-K9 PolarHBondContact O-N 3.12Å; D6-K9 HydrophobicContact CB-CB 4.16Å
7	Q	90.8	Very high	92.3	Very high	120 Å²	120	128.1 Å²	128.1	56%	0.561	62%	0.621	S	S	*	*	T	Hydrogen-bonded Turn	trans	-64	-16.7	-178.8	70.3	-178.9	-68.4	0	0	115.4	R2	R2-Q7 WeakPolarHBondContact CD-O 3.35Å
8	Y	92.8	Very high	92.6	Very high	198 Å²	198	125.1 Å²	125.1	78%	0.776	63%	0.629	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91.8	-11	-179.9	-62.6	-73.9	0	0	0	112.6	D6	D6-Y8 PolarHBondContact O-N 3.49Å; D6-Y8 VanDerWaalsContact O-N 3.1Å; D6-Y8 PolarHBondContact OD1-N 3.45Å
9	K	91.8	Very high	92.9	Very high	109 Å²	109	127.8 Å²	127.8	47%	0.474	65%	0.645	S	S	.	*	P	Polyproline II helix	trans	-93.8	118.5	177.9	-174.1	178.8	164.1	-148.8	0	110.3	D3 D6	D3-K9 IonicContact OD2-NZ 2.81Å; D3-K9 PolarHBondContact OD2-NZ 2.92Å; D3-K9 VanDerWaalsContact N-O 3.08Å; D3-K9 HydrophobicContact CB-CG 4.32Å; D3-K9 HydrophobicContact CB-CD 4.22Å; D3-K9 HydrophobicContact CB-CB 4.05Å; D3-K9 PolarHBondContact N-O 2.94Å; D6-K9 VanDerWaalsContact O-N 3.12Å; D6-K9 PolarHBondContact O-N 3.12Å; D6-K9 HydrophobicContact CB-CB 4.16Å
10	L	89.7	Confident	93.1	Very high	138 Å²	138	125.3 Å²	125.3	72%	0.723	64%	0.636	S	S	*	*	B	Isolated β-bridge	trans	-87.9	127.1	172.1	-166.6	70.1	0	0	0	109.3	R2	R2-L10 HydrophobicContact CG-CD1 4.39Å
11	T	92.3	Very high	93.4	Very high	31 Å²	31	126.2 Å²	126.2	19%	0.19	65%	0.648	C	S	.	*	P	Polyproline II helix	trans	-91.2	156	170	79.4	0	0	0	0	110.4	M1 D3 D13	M1-T11 PolarHBondContact N-O 3.11Å; M1-T11 WeakPolarHBondContact CA-OG1 3.31Å; M1-T11 PolarHBondContact O-OG1 3.14Å; M1-T11 PolarHBondContact O-N 3.1Å; M1-T11 PolarHBondContact N-OG1 3.25Å; M1-T11 WeakPolarHBondContact O-CA 3.48Å; D3-T11 HydrophobicContact CB-CG2 4.13Å; T11-D13 WeakPolarHBondContact CB-OD2 3.4Å; T11-D13 PolarHBondContact O-N 3.08Å; T11-D13 WeakPolarHBondContact OG1-CB 3.45Å; T11-D13 PolarHBondContact OG1-N 2.99Å; T11-D13 PolarHBondContact OG1-OD2 3.01Å
12	E	91.3	Very high	93.9	Very high	195 Å²	195	124.9 Å²	124.9	91%	0.911	65%	0.649	S	S	*	*			trans	-77	0.9	175.1	-59.8	-169.2	164	0	0	113.2	T14	E12-T14 PolarHBondContact O-N 3.12Å
13	D	92.9	Very high	94.3	Very high	106 Å²	106	125.6 Å²	125.6	57%	0.567	65%	0.652	S	S	*	*			trans	-65.2	133.6	-178.3	-54	-46.7	0	0	0	111.6	M1 T11	M1-D13 HydrophobicContact CB-CB 3.99Å; M1-D13 PolarHBondContact N-O 2.74Å; T11-D13 WeakPolarHBondContact CB-OD2 3.4Å; T11-D13 PolarHBondContact O-N 3.08Å; T11-D13 WeakPolarHBondContact OG1-CB 3.45Å; T11-D13 PolarHBondContact OG1-N 2.99Å; T11-D13 PolarHBondContact OG1-OD2 3.01Å
14	T	92.5	Very high	94.6	Very high	133 Å²	133	127.1 Å²	127.1	82%	0.816	67%	0.674	S	S	*	*			trans	-116.2	155.3	175.5	59.6	0	0	0	0	110.3	E12	E12-T14 PolarHBondContact O-N 3.12Å
15	R	94.3	Very high	94.9	Very high	180 Å²	180	126.8 Å²	126.8	68%	0.679	67%	0.67	S	S	*	*			trans	-131.4	141.6	174.4	71.8	178.4	-177.1	170.2	4.8	110.9	L17	R15-L17 HydrophobicContact CG-CD2 4.14Å; R15-L17 HydrophobicContact CG-CG 4.45Å
16	Q	96.9	Very high	95	Very high	182 Å²	182	123.3 Å²	123.3	85%	0.85	66%	0.658	S	S	*	*			trans	-76	129.8	176.2	-61.4	-63.6	78.1	0	0	110.4
17	L	96.4	Very high	95.2	Very high	109 Å²	109	123 Å²	123	57%	0.571	66%	0.659	S	S	*	*			trans	-113.3	-14.7	179.2	-65.2	-179.8	0	0	0	114.1	R15 V20	R15-L17 HydrophobicContact CG-CD2 4.14Å; R15-L17 HydrophobicContact CG-CG 4.45Å; L17-V20 HydrophobicContact CB-CG1 3.77Å
18	G	97.7	Very high	95.5	Very high	74 Å²	74	124.4 Å²	124.4	76%	0.763	68%	0.675	S	S	*	*			trans	69.2	-143.8	-174	0	0	0	0	0	112.3
19	L	97.9	Very high	95.7	Very high	177 Å²	177	121.1 Å²	121.1	93%	0.927	67%	0.671	S	S	*	*	S	Bend	trans	-80.5	126.4	176	179.8	63.4	0	0	0	110.2
20	V	97.5	Very high	95.9	Very high	77 Å²	77	123 Å²	123	47%	0.467	68%	0.684	S	S	.	*			trans	-128.3	154.4	-177.8	-61.6	0	0	0	0	111.9	L17	L17-V20 HydrophobicContact CB-CG1 3.77Å
21	V	98.1	Very high	96.2	Very high	146 Å²	146	119.6 Å²	119.6	89%	0.885	67%	0.671	S	S	*	*			trans	-113.8	117.7	167.1	179.5	0	0	0	0	108
22	C	97.1	Very high	96.5	Very high	96 Å²	96	123.1 Å²	123.1	65%	0.649	69%	0.694	S	S	*	*			trans	-86.5	135	-179.9	-63.7	0	0	0	0	111.1	G24 V27	C22-G24 PolarHBondContact O-N 2.69Å; C22-V27 HydrophobicContact CB-CG2 4.31Å
23	R	98.3	Very high	96.6	Very high	183 Å²	183	122 Å²	122	69%	0.691	69%	0.69	S	S	*	*			trans	-76.2	112.9	175.1	-178.9	-179.7	171.8	163.2	1.2	110.1	T25 S26	R23-T25 VanDerWaalsContact C-N 3.28Å; R23-T25 WeakPolarHBondContact CG-OG1 3.46Å; R23-T25 PolarHBondContact NE-OG1 3.37Å; R23-T25 PolarHBondContact O-N 3.01Å; R23-S26 PolarHBondContact O-N 2.89Å
24	G	97.9	Very high	96.8	Very high	60 Å²	60	124.7 Å²	124.7	62%	0.619	70%	0.704	S	S	*	*	G	3₁₀ helix	trans	-56.4	-35.7	-175.7	0	0	0	0	0	114.8	C22 S26 V27	C22-G24 PolarHBondContact O-N 2.69Å; G24-S26 PolarHBondContact O-N 3.28Å; G24-S26 VanDerWaalsContact O-N 3.16Å; G24-V27 PolarHBondContact O-N 2.89Å
25	T	97.9	Very high	96.9	Very high	117 Å²	117	122.1 Å²	122.1	72%	0.718	70%	0.703	S	S	*	*	G	3₁₀ helix	trans	-67.6	-12.2	177.4	38.2	0	0	0	0	114.5	R23	R23-T25 VanDerWaalsContact C-N 3.28Å; R23-T25 WeakPolarHBondContact CG-OG1 3.46Å; R23-T25 PolarHBondContact NE-OG1 3.37Å; R23-T25 PolarHBondContact O-N 3.01Å
26	S	97.6	Very high	96.9	Very high	86 Å²	86	119.6 Å²	119.6	60%	0.601	70%	0.701	S	S	*	*	G	3₁₀ helix	trans	-103.6	-9.8	176.1	-57.9	0	0	0	0	113.2	R23 G24	R23-S26 PolarHBondContact O-N 2.89Å; G24-S26 PolarHBondContact O-N 3.28Å; G24-S26 VanDerWaalsContact O-N 3.16Å
27	V	96.9	Very high	96.8	Very high	66 Å²	66	118.5 Å²	118.5	40%	0.4	70%	0.696	S	S	.	*			trans	-85.9	128.2	179.4	177.7	0	0	0	0	109.1	C22 G24 I30	C22-V27 HydrophobicContact CB-CG2 4.31Å; G24-V27 PolarHBondContact O-N 2.89Å; V27-I30 HydrophobicContact CG1-CD1 4.21Å; V27-I30 HydrophobicContact CG1-CG1 3.85Å
28	V	98.1	Very high	96.5	Very high	149 Å²	149	118.4 Å²	118.4	90%	0.903	71%	0.711	S	S	*	*			trans	-108.3	-25.4	-179	-64.6	0	0	0	0	113.6
29	L	96.6	Very high	96.2	Very high	130 Å²	130	120.2 Å²	120.2	68%	0.681	70%	0.702	S	S	*	*			trans	-148.8	141.8	-177	-177.8	66.8	0	0	0	110.7
30	I	96.5	Very high	95.9	Very high	148 Å²	148	117.2 Å²	117.2	76%	0.759	69%	0.693	S	S	*	*			trans	-133.2	125.2	168.6	-56.2	178.8	0	0	0	107.6	V27	V27-I30 HydrophobicContact CG1-CD1 4.21Å; V27-I30 HydrophobicContact CG1-CG1 3.85Å
31	C	95.9	Very high	95.6	Very high	67 Å²	67	117.8 Å²	117.8	45%	0.453	69%	0.693	S	S	.	*			trans	-135	151.4	175.3	-64.8	0	0	0	0	109.6	M36	C31-M36 HydrophobicContact CB-CE 3.84Å
32	P	97.8	Very high	95.1	Very high	104 Å²	104	115.3 Å²	115.3	68%	0.675	68%	0.68	S	S	*	*			trans	-62.4	145	169.7	29.1	-34.5	0	0	0	110.1
33	Q	94.1	Very high	94.7	Very high	173 Å²	173	119.3 Å²	119.3	81%	0.808	69%	0.687	S	S	*	*	S	Bend	trans	-78.1	-37.3	174.4	-173.2	-173.3	-5.6	0	0	111.3	G35 M36	Q33-G35 PolarHBondContact O-N 2.78Å; Q33-M36 WeakPolarHBondContact O-CB 3.45Å; Q33-M36 PolarHBondContact O-N 3.41Å
34	D	96.9	Very high	94.3	Very high	162 Å²	162	116.1 Å²	116.1	87%	0.866	68%	0.683	S	S	*	*	T	Hydrogen-bonded Turn	trans	-64.9	127.8	-179.3	-168.7	27.4	0	0	0	110.6	M36	D34-M36 VanDerWaalsContact C-N 3.33Å
35	G	94.3	Very high	93.3	Very high	78 Å²	78	121.6 Å²	121.6	80%	0.804	69%	0.692	S	S	*	*	T	Hydrogen-bonded Turn	trans	80.2	1.2	-172.9	0	0	0	0	0	115.9	Q33	Q33-G35 PolarHBondContact O-N 2.78Å
36	M	95.1	Very high	91.9	Very high	128 Å²	128	124.4 Å²	124.4	63%	0.631	70%	0.697	S	S	*	*			trans	-86.5	126.3	171.9	-180	-176.3	-74.9	0	0	110.5	C31 Q33 D34	C31-M36 HydrophobicContact CB-CE 3.84Å; Q33-M36 WeakPolarHBondContact O-CB 3.45Å; Q33-M36 PolarHBondContact O-N 3.41Å; D34-M36 VanDerWaalsContact C-N 3.33Å
37	E	94.3	Very high	90.3	Very high	158 Å²	158	129.1 Å²	129.1	74%	0.738	71%	0.709	S	S	*	*			trans	-135.3	149.7	169.6	65.6	-179.6	173.4	0	0	111.2	I39	E37-I39 HydrophobicContact CG-CG2 3.92Å
38	A	90.7	Very high	88.3	Confident	108 Å²	108	133.4 Å²	133.4	89%	0.893	73%	0.73	S	S	*	*			trans	-78.2	123.8	169.3	0	0	0	0	0	108.6
39	I	91.7	Very high	85.8	Confident	112 Å²	112	134.7 Å²	134.7	57%	0.574	76%	0.756	S	S	*	*			trans	-107.3	151.8	179	62.7	169	0	0	0	111.1	E37	E37-I39 HydrophobicContact CG-CG2 3.92Å
40	P	90.4	Very high	85.2	Confident	113 Å²	113	134.9 Å²	134.9	73%	0.734	76%	0.76	S	S	*	*			trans	-61	157.9	167.3	28.5	-35.7	0	0	0	110.4	P42	P40-P42 VanDerWaalsContact O-CD 3.31Å; P40-P42 VanDerWaalsContact O-N 3.09Å; P40-P42 WeakPolarHBondContact O-CD 3.41Å
41	N	90.8	Very high	84.7	Confident	89 Å²	89	134.2 Å²	134.2	48%	0.476	76%	0.76	S	S	.	*			trans	-58.8	116.2	176.6	176.6	-7.8	0	0	0	109.9	F43 I44	N41-F43 PolarHBondContact O-N 3.04Å; N41-F43 VanDerWaalsContact O-N 3.12Å; N41-F43 WeakPolarHBondContact OD1-CD2 3.36Å; N41-F43 PolarHBondContact OD1-N 3.35Å; N41-I44 HydrophobicContact CB-CD1 3.78Å; N41-I44 HydrophobicContact CB-CG1 3.89Å; N41-I44 PolarHBondContact O-N 3.18Å
42	P	89.3	Confident	84	Confident	95 Å²	95	137.9 Å²	137.9	62%	0.617	78%	0.777	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72.9	-6.2	-172.2	31.3	-36.7	0	0	0	113.5	P40	P40-P42 VanDerWaalsContact O-CD 3.31Å; P40-P42 VanDerWaalsContact O-N 3.09Å; P40-P42 WeakPolarHBondContact O-CD 3.41Å
43	F	88.6	Confident	83.2	Confident	180 Å²	180	139.9 Å²	139.9	79%	0.789	78%	0.783	S	S	*	*	T	Hydrogen-bonded Turn	trans	-101.1	-4.3	179.6	-55.6	-73.2	0	0	0	113.4	N41 Q45	N41-F43 PolarHBondContact O-N 3.04Å; N41-F43 VanDerWaalsContact O-N 3.12Å; N41-F43 WeakPolarHBondContact OD1-CD2 3.36Å; N41-F43 PolarHBondContact OD1-N 3.35Å; F43-Q45 PolarHBondContact O-N 2.96Å; F43-Q45 VanDerWaalsContact O-N 3.14Å
44	I	88.1	Confident	82.5	Confident	116 Å²	116	137.9 Å²	137.9	60%	0.595	78%	0.781	S	S	*	*	S	Bend	trans	-70.2	111.7	167.9	-62.9	176.3	0	0	0	105.6	N41 Q46	N41-I44 HydrophobicContact CB-CD1 3.78Å; N41-I44 HydrophobicContact CB-CG1 3.89Å; N41-I44 PolarHBondContact O-N 3.18Å; I44-Q46 PolarHBondContact O-N 2.83Å
45	Q	78.8	Confident	81.6	Confident	175 Å²	175	136.3 Å²	136.3	82%	0.818	78%	0.776	S	S	*	*			trans	-55.2	114.4	168.2	-73.8	176.3	-17	0	0	106.5	F43 Q47	F43-Q45 PolarHBondContact O-N 2.96Å; F43-Q45 VanDerWaalsContact O-N 3.14Å; Q45-Q47 VanDerWaalsContact C-N 3.28Å; Q45-Q47 PolarHBondContact O-N 3.18Å
46	Q	68.1	Low	80.7	Confident	176 Å²	176	140.4 Å²	140.4	82%	0.822	77%	0.774	S	S	*	*			trans	-55.2	103.8	164.2	-102.6	145.7	-27	0	0	105.3	I44 D48	I44-Q46 PolarHBondContact O-N 2.83Å; Q46-D48 VanDerWaalsContact C-N 3.29Å; Q46-D48 PolarHBondContact O-N 3.16Å
47	Q	62.5	Low	79.6	Confident	184 Å²	184	141.4 Å²	141.4	86%	0.86	79%	0.785	S	S	*	*			trans	-60.5	105.9	165.7	-78.9	173	-6	0	0	104.3	Q45 A49	Q45-Q47 VanDerWaalsContact C-N 3.28Å; Q45-Q47 PolarHBondContact O-N 3.18Å; Q47-A49 PolarHBondContact O-N 3.33Å; Q47-A49 VanDerWaalsContact O-N 3.11Å
48	D	55.8	Low	78.3	Confident	157 Å²	157	140 Å²	140	84%	0.84	79%	0.789	S	S	*	*			trans	-48.5	118.9	172	-69.1	-54.2	0	0	0	107.5	Q46	Q46-D48 VanDerWaalsContact C-N 3.29Å; Q46-D48 PolarHBondContact O-N 3.16Å
49	A	45.4	Very low	77.2	Confident	175 Å²	175	142.9 Å²	142.9	100%	1.446	78%	0.779	S	S	*	*			trans	-73.4	0	175.3	0	0	0	0	0	110.9	Q47	Q47-A49 PolarHBondContact O-N 3.33Å; Q47-A49 VanDerWaalsContact O-N 3.11Å

Retrieved 49 of 49 residues in 13.1 ms (Link to these results)

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