A0A087X6C2_POEFO Loading...

Prefoldin subunit 2

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

AlphaFold DB (A0A3B3TRC2), UniProt , Accession A0A087X6C2, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 162 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	39	Very low	40	Very low	250 Å²	250	130.8 Å²	130.8	100%	1.232	83%	0.831	S	S	*	*				0	120	0	-63.2	176.3	168.3	0	0	106.6
2	A	40.5	Very low	39.5	Very low	94 Å²	94	131.6 Å²	131.6	78%	0.777	83%	0.834	S	S	*	*			cis	-157.2	121.6	-7.4	0	0	0	0	0	104
3	A	44	Very low	39	Very low	100 Å²	100	129.3 Å²	129.3	83%	0.826	82%	0.824	S	S	*	*				38	112.4	106.4	0	0	0	0	0	116.3
4	N	42.4	Very low	39.4	Very low	155 Å²	155	128.9 Å²	128.9	83%	0.829	83%	0.827	S	S	*	*				-158.2	109.3	124.4	-150.1	31.1	0	0	0	113.3
5	S	46.3	Very low	39	Very low	88 Å²	88	127.3 Å²	127.3	62%	0.615	82%	0.821	S	S	*	*			trans	-45.9	164.4	142.5	41	0	0	0	0	112.3
6	S	40.3	Very low	39.4	Very low	101 Å²	101	124.7 Å²	124.7	71%	0.706	83%	0.825	S	S	*	*			cis	179.9	163.5	8.9	33.7	0	0	0	0	107.8
7	S	38	Very low	39.1	Very low	102 Å²	102	121.6 Å²	121.6	71%	0.713	82%	0.82	S	S	*	*			trans	69.1	119	149.9	73.3	0	0	0	0	119.9
8	T	36	Very low	38.8	Very low	139 Å²	139	119.2 Å²	119.2	85%	0.853	82%	0.819	S	S	*	*				-168.1	129.8	99.5	34.3	0	0	0	0	109.5
9	G	41.6	Very low	38.9	Very low	85 Å²	85	116.9 Å²	116.9	88%	0.876	82%	0.817	S	S	*	*			trans	-76.6	143.6	170	0	0	0	0	0	110.7
10	S	34.7	Very low	39.2	Very low	115 Å²	115	120.9 Å²	120.9	80%	0.804	82%	0.819	S	S	*	*			trans	-128.2	120.8	155.2	51.1	0	0	0	0	108.1	T12	S10-T12 PolarHBondContact O-N 3.36Å
11	K	37.1	Very low	39.8	Very low	210 Å²	210	124.5 Å²	124.5	91%	0.913	82%	0.824	S	S	*	*			trans	-58.9	118.6	178	-71.6	168.4	171.6	175.7	0	108.8	S13	K11-S13 PolarHBondContact O-N 3.16Å
12	T	33.8	Very low	41	Very low	140 Å²	140	117.8 Å²	117.8	86%	0.859	80%	0.802	S	S	*	*			trans	-67.8	102.8	161	-51.5	0	0	0	0	107.3	S10 S14	S10-T12 PolarHBondContact O-N 3.36Å; T12-S14 PolarHBondContact O-N 3.45Å
13	S	34.1	Very low	42.7	Very low	102 Å²	102	116.1 Å²	116.1	71%	0.713	79%	0.793	S	S	*	*			trans	-63	111.6	170.2	38	0	0	0	0	109.3	K11 S15	K11-S13 PolarHBondContact O-N 3.16Å; S13-S15 PolarHBondContact O-N 2.74Å; S13-S15 VanDerWaalsContact O-N 3.17Å
14	S	44	Very low	44.7	Very low	123 Å²	123	114 Å²	114	86%	0.86	77%	0.771	S	S	*	*			trans	-60.4	108.3	154.8	44.1	0	0	0	0	109	T12	T12-S14 PolarHBondContact O-N 3.45Å
15	S	34.2	Very low	47	Very low	106 Å²	106	109.1 Å²	109.1	74%	0.741	75%	0.749	S	S	*	*			trans	-146.6	99.8	159.2	130.5	0	0	0	0	103.7	S13	S13-S15 PolarHBondContact O-N 2.74Å; S13-S15 VanDerWaalsContact O-N 3.17Å
16	G	45.4	Very low	49	Very low	85 Å²	85	107.8 Å²	107.8	88%	0.876	74%	0.743	S	S	*	*				76.8	45.9	57.9	0	0	0	0	0	110.1
17	G	33	Very low	51.4	Low	73 Å²	73	110.7 Å²	110.7	75%	0.753	75%	0.746	S	S	*	*			trans	-111	89	171.3	0	0	0	0	0	109.4	G19	G17-G19 PolarHBondContact O-N 2.55Å
18	G	34.6	Very low	54	Low	77 Å²	77	111.1 Å²	111.1	79%	0.794	74%	0.737	S	S	*	*			trans	-55.3	119.9	177.8	0	0	0	0	0	111.1	K20	G18-K20 PolarHBondContact O-N 3.46Å
19	G	39.5	Very low	56.7	Low	76 Å²	76	104.7 Å²	104.7	78%	0.784	70%	0.697	S	S	*	*			trans	-60.1	99.8	168.2	0	0	0	0	0	109	G17 Q21	G17-G19 PolarHBondContact O-N 2.55Å; G19-Q21 PolarHBondContact O-N 3.18Å; G19-Q21 VanDerWaalsContact O-N 3.07Å
20	K	46.1	Very low	59.1	Low	196 Å²	196	101.8 Å²	101.8	85%	0.852	66%	0.662	S	S	*	*			trans	-66.6	106.2	162.3	-154	170.8	-174.2	-178.8	0	104.5	G18 S22	G18-K20 PolarHBondContact O-N 3.46Å; K20-S22 PolarHBondContact O-N 3.09Å
21	Q	51.1	Low	61.9	Low	197 Å²	197	99 Å²	99	92%	0.921	65%	0.646	S	S	*	*			trans	-59.4	90.6	169.8	-73	-179.2	-56.2	0	0	107	G19 G23	G19-Q21 PolarHBondContact O-N 3.18Å; G19-Q21 VanDerWaalsContact O-N 3.07Å; Q21-G23 PolarHBondContact O-N 3.01Å
22	S	63.8	Low	64.7	Low	110 Å²	110	90.7 Å²	90.7	77%	0.769	61%	0.613	S	S	*	*			trans	-66.6	115.6	170.1	49.2	0	0	0	0	106	K20	K20-S22 PolarHBondContact O-N 3.09Å
23	G	77.8	Confident	67.6	Low	58 Å²	58	84.3 Å²	84.3	60%	0.598	57%	0.574	S	S	*	*	P	Polyproline II helix	trans	-54.5	168.3	171.4	0	0	0	0	0	111.8	Q21	Q21-G23 PolarHBondContact O-N 3.01Å
24	P	84.8	Confident	70.5	Confident	57 Å²	57	84.2 Å²	84.2	37%	0.37	56%	0.562	S	S	.	*	P	Polyproline II helix	trans	-55.3	143.6	179.7	24.3	-33.4	0	0	0	111	Q28 V29 Y125	P24-Q28 HydrophobicContact CB-CB 4.15Å; P24-V29 HydrophobicContact CB-CG2 4.07Å; P24-V29 HydrophobicContact CG-CG2 3.86Å; P24-Y125 HydrophobicContact CG-CE1 3.96Å; P24-Y125 WeakPolarHBondContact CG-OH 3.41Å
25	S	91.8	Very high	73	Confident	52 Å²	52	85.4 Å²	85.4	36%	0.364	55%	0.547	S	S	.	.	P	Polyproline II helix	trans	-64.6	158	176.1	74.3	0	0	0	0	111	E27 Q28 V29	S25-E27 PolarHBondContact O-N 3.44Å; S25-Q28 WeakPolarHBondContact O-CB 3.26Å; S25-Q28 PolarHBondContact O-N 3.26Å; S25-Q28 VanDerWaalsContact OG-CG 3.28Å; S25-Q28 WeakPolarHBondContact OG-CG 3.34Å; S25-Q28 PolarHBondContact OG-N 2.98Å; S25-V29 WeakPolarHBondContact O-CG2 3.34Å; S25-V29 PolarHBondContact O-N 3Å
26	A	88.4	Confident	76	Confident	59 Å²	59	81 Å²	81	49%	0.488	52%	0.515	S	S	.	.	H	α-helix	trans	-55.1	-40	177.5	0	0	0	0	0	112.2	V29 V30 V161	A26-V29 PolarHBondContact O-N 3.21Å; A26-V30 WeakPolarHBondContact O-CG2 3.46Å; A26-V30 PolarHBondContact O-N 2.89Å; A26-V161 HydrophobicContact CB-CB 4.29Å; A26-V161 HydrophobicContact CB-CG1 4.27Å
27	E	90.1	Very high	78.4	Confident	162 Å²	162	79.8 Å²	79.8	76%	0.757	48%	0.484	S	S	*	.	H	α-helix	trans	-63	-42.3	174.9	-65.4	178.2	173.7	0	0	112.3	S25 V29 V30 A31	S25-E27 PolarHBondContact O-N 3.44Å; E27-V29 VanDerWaalsContact C-N 3.33Å; E27-V29 PolarHBondContact O-N 3Å; E27-V30 PolarHBondContact O-N 2.93Å; E27-A31 VanDerWaalsContact O-CB 3.3Å; E27-A31 WeakPolarHBondContact O-CB 3.39Å; E27-A31 PolarHBondContact O-N 3.39Å
28	Q	92.5	Very high	81.4	Confident	112 Å²	112	80.7 Å²	80.7	52%	0.523	47%	0.469	S	S	.	.	H	α-helix	trans	-65.5	-37.4	176.9	-73.7	172.4	-22.1	0	0	112.1	P24 S25 T32	P24-Q28 HydrophobicContact CB-CB 4.15Å; S25-Q28 WeakPolarHBondContact O-CB 3.26Å; S25-Q28 PolarHBondContact O-N 3.26Å; S25-Q28 VanDerWaalsContact OG-CG 3.28Å; S25-Q28 WeakPolarHBondContact OG-CG 3.34Å; S25-Q28 PolarHBondContact OG-N 2.98Å; Q28-T32 VanDerWaalsContact O-CB 3.32Å; Q28-T32 WeakPolarHBondContact O-CB 3.37Å; Q28-T32 PolarHBondContact O-N 3.27Å; Q28-T32 PolarHBondContact O-OG1 3.05Å
29	V	93.3	Very high	84.4	Confident	3 Å²	3	80.2 Å²	80.2	2%	0.018	45%	0.446	C	S	.	.	H	α-helix	trans	-62	-51.2	174.9	169	0	0	0	0	110.3	P24 S25 A26 E27 A31 T32 F33 Y121 Y125 I127 V161	P24-V29 HydrophobicContact CB-CG2 4.07Å; P24-V29 HydrophobicContact CG-CG2 3.86Å; S25-V29 WeakPolarHBondContact O-CG2 3.34Å; S25-V29 PolarHBondContact O-N 3Å; A26-V29 PolarHBondContact O-N 3.21Å; E27-V29 VanDerWaalsContact C-N 3.33Å; E27-V29 PolarHBondContact O-N 3Å; V29-A31 PolarHBondContact O-N 3Å; V29-T32 PolarHBondContact O-N 3.16Å; V29-F33 WeakPolarHBondContact O-CB 3.15Å; V29-F33 PolarHBondContact O-N 2.92Å; V29-Y121 WeakPolarHBondContact CA-OH 3.23Å; V29-Y121 HydrophobicContact CG1-CE1 3.85Å; V29-Y121 WeakPolarHBondContact O-CE1 3.39Å; V29-Y125 HydrophobicContact CB-CG 4.48Å; V29-Y125 VanDerWaalsContact CG1-CB 3.49Å; V29-Y125 HydrophobicContact CG1-CD1 4.05Å; V29-Y125 HydrophobicContact CG1-CD2 3.98Å; V29-Y125 HydrophobicContact CG1-CG 3.58Å; V29-Y125 HydrophobicContact CG2-CD1 3.64Å; V29-Y125 HydrophobicContact CG2-CD2 4.43Å; V29-Y125 HydrophobicContact CG2-CE1 3.76Å; V29-Y125 HydrophobicContact CG2-CG 4Å; V29-I127 HydrophobicContact CG1-CD1 3.76Å; V29-I127 HydrophobicContact CG1-CG1 4.15Å; V29-V161 HydrophobicContact CB-CG2 4.32Å; V29-V161 HydrophobicContact CG1-CG2 3.82Å
30	V	91.8	Very high	87.1	Confident	24 Å²	24	79.4 Å²	79.4	15%	0.145	42%	0.422	C	S	.	.	H	α-helix	trans	-59.8	-48	177.7	171.4	0	0	0	0	111.4	A26 E27 T32 F33 Q34 V159 V161	A26-V30 WeakPolarHBondContact O-CG2 3.46Å; A26-V30 PolarHBondContact O-N 2.89Å; E27-V30 PolarHBondContact O-N 2.93Å; V30-T32 VanDerWaalsContact C-N 3.31Å; V30-T32 PolarHBondContact O-N 3.44Å; V30-F33 PolarHBondContact O-N 3.06Å; V30-Q34 HydrophobicContact CG1-CG 4.33Å; V30-Q34 WeakPolarHBondContact O-CG 3.37Å; V30-Q34 PolarHBondContact O-N 3.45Å; V30-V159 HydrophobicContact CB-CG1 4.35Å; V30-V159 HydrophobicContact CG1-CB 3.71Å; V30-V159 HydrophobicContact CG1-CG1 3.93Å; V30-V159 HydrophobicContact CG1-CG2 4.43Å; V30-V159 HydrophobicContact CG2-CB 4.3Å; V30-V159 HydrophobicContact CG2-CG1 3.89Å; V30-V161 HydrophobicContact CG2-CG2 3.45Å; V30-V161 VanDerWaalsContact CG2-CG2 3.45Å
31	A	93.9	Very high	89.5	Confident	57 Å²	57	76.2 Å²	76.2	47%	0.471	40%	0.404	S	S	.	.	H	α-helix	trans	-60.6	-42	-179.3	0	0	0	0	0	111.8	E27 V29 Q34 R35	E27-A31 VanDerWaalsContact O-CB 3.3Å; E27-A31 WeakPolarHBondContact O-CB 3.39Å; E27-A31 PolarHBondContact O-N 3.39Å; V29-A31 PolarHBondContact O-N 3Å; A31-Q34 PolarHBondContact O-N 3.02Å; A31-R35 WeakPolarHBondContact O-CB 3.31Å; A31-R35 PolarHBondContact O-N 3.42Å
32	T	95.4	Very high	91.7	Very high	36 Å²	36	71 Å²	71	22%	0.221	38%	0.383	C	S	.	.	H	α-helix	trans	-64.2	-46	177	-59.4	0	0	0	0	111.2	Q28 V29 V30 Q34 R35 M36 Y121	Q28-T32 VanDerWaalsContact O-CB 3.32Å; Q28-T32 WeakPolarHBondContact O-CB 3.37Å; Q28-T32 PolarHBondContact O-N 3.27Å; Q28-T32 PolarHBondContact O-OG1 3.05Å; V29-T32 PolarHBondContact O-N 3.16Å; V30-T32 VanDerWaalsContact C-N 3.31Å; V30-T32 PolarHBondContact O-N 3.44Å; T32-Q34 PolarHBondContact O-N 3.21Å; T32-R35 WeakPolarHBondContact O-CB 3.44Å; T32-R35 PolarHBondContact O-N 3.26Å; T32-M36 HydrophobicContact CG2-SD 4.16Å; T32-M36 WeakPolarHBondContact O-CG 3.45Å; T32-M36 PolarHBondContact O-N 3.48Å; T32-Y121 WeakPolarHBondContact CB-OH 3.47Å; T32-Y121 HydrophobicContact CG2-CE1 4.44Å; T32-Y121 HydrophobicContact CG2-CE2 4.15Å
33	F	95.1	Very high	93.3	Very high	6 Å²	6	67.3 Å²	67.3	3%	0.026	35%	0.354	C	S	.	.	H	α-helix	trans	-61.2	-43.7	177.6	-177.6	-107.3	0	0	0	112.3	V29 V30 R35 M36 R37 L118 Y121 R122 I127 L129 V159	V29-F33 WeakPolarHBondContact O-CB 3.15Å; V29-F33 PolarHBondContact O-N 2.92Å; V30-F33 PolarHBondContact O-N 3.06Å; F33-R35 PolarHBondContact O-N 2.88Å; F33-M36 PolarHBondContact O-N 3.33Å; F33-R37 HydrophobicContact CE1-CG 4.28Å; F33-R37 HydrophobicContact CZ-CG 4.36Å; F33-R37 WeakPolarHBondContact O-CG 3.48Å; F33-R37 PolarHBondContact O-N 2.77Å; F33-L118 HydrophobicContact CD2-CD2 3.66Å; F33-L118 HydrophobicContact CE2-CD2 3.53Å; F33-L118 HydrophobicContact CZ-CD2 4.29Å; F33-Y121 HydrophobicContact CB-CD1 4.01Å; F33-Y121 HydrophobicContact CB-CE1 3.99Å; F33-Y121 AromaticContact CD2-CD1 3.96Å; F33-Y121 HydrophobicContact CD2-CD1 3.96Å; F33-Y121 HydrophobicContact CG-CD1 4.45Å; F33-R122 HydrophobicContact CE2-CB 4.01Å; F33-R122 HydrophobicContact CZ-CB 4.46Å; F33-I127 HydrophobicContact CB-CD1 3.68Å; F33-I127 HydrophobicContact CD1-CD1 4.26Å; F33-I127 HydrophobicContact CD1-CG2 3.98Å; F33-I127 HydrophobicContact CD2-CD1 3.81Å; F33-I127 HydrophobicContact CE1-CG2 4.01Å; F33-I127 HydrophobicContact CG-CD1 3.66Å; F33-I127 HydrophobicContact CG-CG2 4.41Å; F33-I127 HydrophobicContact CZ-CG2 4.48Å; F33-L129 HydrophobicContact CE1-CD1 4.36Å; F33-L129 HydrophobicContact CE1-CD2 4.13Å; F33-L129 HydrophobicContact CE1-CG 4.3Å; F33-L129 HydrophobicContact CZ-CD1 4.39Å; F33-V159 HydrophobicContact CD1-CG1 4.1Å; F33-V159 HydrophobicContact CD1-CG2 4.45Å
34	Q	94.6	Very high	94.2	Very high	100 Å²	100	66.6 Å²	66.6	47%	0.467	34%	0.342	S	S	.	.	H	α-helix	trans	-62.8	-41.9	175.7	-71.6	-172.9	22.6	0	0	112	V30 A31 T32 M36 R37 Q38 V159	V30-Q34 HydrophobicContact CG1-CG 4.33Å; V30-Q34 WeakPolarHBondContact O-CG 3.37Å; V30-Q34 PolarHBondContact O-N 3.45Å; A31-Q34 PolarHBondContact O-N 3.02Å; T32-Q34 PolarHBondContact O-N 3.21Å; Q34-M36 PolarHBondContact O-N 3.04Å; Q34-R37 PolarHBondContact O-N 3.38Å; Q34-Q38 PolarHBondContact O-N 2.78Å; Q34-V159 HydrophobicContact CG-CG2 4.15Å
35	R	96.3	Very high	94.9	Very high	147 Å²	147	67.7 Å²	67.7	56%	0.555	35%	0.351	S	S	*	.	H	α-helix	trans	-59.4	-46.9	174.7	-172.9	-177.8	67.6	-149	-5.2	111.3	A31 T32 F33 R37 Q38 E39	A31-R35 WeakPolarHBondContact O-CB 3.31Å; A31-R35 PolarHBondContact O-N 3.42Å; T32-R35 WeakPolarHBondContact O-CB 3.44Å; T32-R35 PolarHBondContact O-N 3.26Å; F33-R35 PolarHBondContact O-N 2.88Å; R35-R37 VanDerWaalsContact C-N 3.33Å; R35-R37 PolarHBondContact O-N 2.69Å; R35-Q38 PolarHBondContact O-N 2.69Å; R35-Q38 VanDerWaalsContact O-N 3.13Å; R35-E39 WeakPolarHBondContact CG-OE1 3.39Å; R35-E39 IonicContact NE-OE1 3.58Å; R35-E39 WeakPolarHBondContact O-CG 3.4Å; R35-E39 PolarHBondContact O-N 2.97Å
36	M	96.4	Very high	95.2	Very high	14 Å²	14	69.1 Å²	69.1	7%	0.069	35%	0.351	C	S	.	.	H	α-helix	trans	-60.7	-39.9	177.7	-69.6	173.6	68.9	0	0	112.4	T32 F33 Q34 E39 Q40 E117 L118 Y121	T32-M36 HydrophobicContact CG2-SD 4.16Å; T32-M36 WeakPolarHBondContact O-CG 3.45Å; T32-M36 PolarHBondContact O-N 3.48Å; F33-M36 PolarHBondContact O-N 3.33Å; Q34-M36 PolarHBondContact O-N 3.04Å; M36-E39 PolarHBondContact O-N 3.14Å; M36-Q40 PolarHBondContact O-N 3.14Å; M36-E117 HydrophobicContact CE-CB 3.57Å; M36-L118 HydrophobicContact CB-CD2 3.53Å; M36-L118 HydrophobicContact CB-CG 4.05Å; M36-L118 HydrophobicContact CE-CD2 4.38Å; M36-L118 HydrophobicContact CE-CG 4.25Å; M36-Y121 HydrophobicContact SD-CD2 4.39Å; M36-Y121 HydrophobicContact SD-CG 4.3Å
37	R	95.7	Very high	95.6	Very high	60 Å²	60	66.5 Å²	66.5	23%	0.226	33%	0.329	C	S	.	.	H	α-helix	trans	-64.3	-41.1	173.8	-71.7	-173.6	75.4	-168.1	12.3	112	F33 Q34 R35 Q40 R41 L118	F33-R37 HydrophobicContact CE1-CG 4.28Å; F33-R37 HydrophobicContact CZ-CG 4.36Å; F33-R37 WeakPolarHBondContact O-CG 3.48Å; F33-R37 PolarHBondContact O-N 2.77Å; Q34-R37 PolarHBondContact O-N 3.38Å; R35-R37 VanDerWaalsContact C-N 3.33Å; R35-R37 PolarHBondContact O-N 2.69Å; R37-Q40 PolarHBondContact O-N 3.32Å; R37-R41 WeakPolarHBondContact O-CG 3.05Å; R37-R41 PolarHBondContact O-N 3Å; R37-L118 HydrophobicContact CG-CD1 4.23Å; R37-L118 HydrophobicContact CG-CD2 3.69Å
38	Q	96.8	Very high	96	Very high	91 Å²	91	60.7 Å²	60.7	43%	0.425	31%	0.309	S	S	.	.	H	α-helix	trans	-64.7	-42.9	177.3	-170.4	60.1	44.6	0	0	111.1	Q34 R35 Q40 R41 N42	Q34-Q38 PolarHBondContact O-N 2.78Å; R35-Q38 PolarHBondContact O-N 2.69Å; R35-Q38 VanDerWaalsContact O-N 3.13Å; Q38-Q40 VanDerWaalsContact C-N 3.33Å; Q38-Q40 PolarHBondContact O-N 2.88Å; Q38-R41 PolarHBondContact O-N 2.95Å; Q38-N42 PolarHBondContact NE2-OD1 3.16Å; Q38-N42 WeakPolarHBondContact O-CB 3.43Å; Q38-N42 PolarHBondContact O-N 2.91Å; Q38-N42 PolarHBondContact O-OD1 2.88Å
39	E	97.1	Very high	96.2	Very high	68 Å²	68	60 Å²	60	32%	0.318	31%	0.306	S	S	.	.	H	α-helix	trans	-56.9	-45.8	173.7	-72.7	168.2	-164.8	0	0	111.3	R35 M36 R41 N42 M43 K114	R35-E39 WeakPolarHBondContact CG-OE1 3.39Å; R35-E39 IonicContact NE-OE1 3.58Å; R35-E39 WeakPolarHBondContact O-CG 3.4Å; R35-E39 PolarHBondContact O-N 2.97Å; M36-E39 PolarHBondContact O-N 3.14Å; E39-R41 PolarHBondContact O-N 3.04Å; E39-N42 PolarHBondContact O-N 3.19Å; E39-M43 WeakPolarHBondContact O-CG 3.27Å; E39-M43 PolarHBondContact O-N 3.12Å; E39-K114 WeakPolarHBondContact OE2-CE 3.25Å; E39-K114 IonicContact OE2-NZ 2.73Å; E39-K114 PolarHBondContact OE2-NZ 3.04Å
40	Q	96	Very high	96.5	Very high	58 Å²	58	60.8 Å²	60.8	27%	0.271	31%	0.31	S	S	.	.	H	α-helix	trans	-61.4	-43.9	177.3	-165.3	-174	29.9	0	0	112.7	M36 R37 Q38 M43 A44 M111 K114 L118	M36-Q40 PolarHBondContact O-N 3.14Å; R37-Q40 PolarHBondContact O-N 3.32Å; Q38-Q40 VanDerWaalsContact C-N 3.33Å; Q38-Q40 PolarHBondContact O-N 2.88Å; Q40-M43 PolarHBondContact O-N 3.31Å; Q40-A44 PolarHBondContact O-N 3.12Å; Q40-M111 HydrophobicContact CG-CG 3.91Å; Q40-K114 HydrophobicContact CB-CG 4.4Å; Q40-L118 HydrophobicContact CB-CD1 4.15Å
41	R	96.5	Very high	96.8	Very high	129 Å²	129	64.2 Å²	64.2	49%	0.487	32%	0.324	S	S	.	.	H	α-helix	trans	-65.5	-37.8	176.9	-71.2	172.8	179.7	168.2	-3.3	112.6	R37 Q38 E39 M43 A44 S45	R37-R41 WeakPolarHBondContact O-CG 3.05Å; R37-R41 PolarHBondContact O-N 3Å; Q38-R41 PolarHBondContact O-N 2.95Å; E39-R41 PolarHBondContact O-N 3.04Å; R41-M43 VanDerWaalsContact C-N 3.35Å; R41-A44 PolarHBondContact O-N 3.3Å; R41-S45 PolarHBondContact O-N 2.9Å; R41-S45 PolarHBondContact O-OG 3.04Å
42	N	97.5	Very high	97	Very high	87 Å²	87	67.3 Å²	67.3	47%	0.465	33%	0.33	S	S	.	.	H	α-helix	trans	-64.3	-42.5	176.3	-68.3	-7.4	0	0	0	110.7	Q38 E39 S45 K46	Q38-N42 PolarHBondContact NE2-OD1 3.16Å; Q38-N42 WeakPolarHBondContact O-CB 3.43Å; Q38-N42 PolarHBondContact O-N 2.91Å; Q38-N42 PolarHBondContact O-OD1 2.88Å; E39-N42 PolarHBondContact O-N 3.19Å; N42-S45 PolarHBondContact O-N 3.39Å; N42-K46 PolarHBondContact O-N 3.16Å
43	M	97.8	Very high	97.1	Very high	34 Å²	34	68 Å²	68	17%	0.167	33%	0.332	C	S	.	.	H	α-helix	trans	-60.1	-46.6	174.1	-74.2	-173.2	-71.1	0	0	111.8	E39 Q40 R41 S45 K46 A47 I107 Q110 M111 K114	E39-M43 WeakPolarHBondContact O-CG 3.27Å; E39-M43 PolarHBondContact O-N 3.12Å; Q40-M43 PolarHBondContact O-N 3.31Å; R41-M43 VanDerWaalsContact C-N 3.35Å; M43-S45 VanDerWaalsContact C-N 3.33Å; M43-S45 PolarHBondContact O-N 3.3Å; M43-K46 PolarHBondContact O-N 3.17Å; M43-A47 PolarHBondContact O-N 3.33Å; M43-I107 HydrophobicContact CB-CG2 3.98Å; M43-I107 WeakPolarHBondContact O-CG2 3.47Å; M43-Q110 HydrophobicContact SD-CB 3.85Å; M43-M111 HydrophobicContact CB-CB 4.46Å; M43-M111 HydrophobicContact CE-CB 4.43Å; M43-K114 HydrophobicContact CE-CB 3.71Å; M43-K114 HydrophobicContact CE-CG 3.88Å
44	A	96.8	Very high	97.2	Very high	43 Å²	43	68.9 Å²	68.9	36%	0.355	34%	0.337	S	S	.	.	H	α-helix	trans	-59.5	-43.3	176.7	0	0	0	0	0	112.3	Q40 R41 K46 A47 A48 M111	Q40-A44 PolarHBondContact O-N 3.12Å; R41-A44 PolarHBondContact O-N 3.3Å; A44-K46 VanDerWaalsContact C-N 3.33Å; A44-K46 PolarHBondContact O-N 3.43Å; A44-A47 PolarHBondContact O-N 3.42Å; A44-A48 PolarHBondContact O-N 2.8Å; A44-A48 VanDerWaalsContact O-N 3.07Å; A44-M111 HydrophobicContact CB-SD 3.78Å
45	S	98.1	Very high	97.3	Very high	79 Å²	79	69.2 Å²	69.2	55%	0.552	34%	0.342	S	S	*	.	H	α-helix	trans	-63.2	-40.9	177.8	-53.9	0	0	0	0	111.5	R41 N42 M43 A48 E49	R41-S45 PolarHBondContact O-N 2.9Å; R41-S45 PolarHBondContact O-OG 3.04Å; N42-S45 PolarHBondContact O-N 3.39Å; M43-S45 VanDerWaalsContact C-N 3.33Å; M43-S45 PolarHBondContact O-N 3.3Å; S45-A48 PolarHBondContact O-N 2.98Å; S45-E49 PolarHBondContact O-N 2.93Å; S45-E49 VanDerWaalsContact O-N 3.13Å
46	K	98.1	Very high	97.4	Very high	83 Å²	83	68.3 Å²	68.3	36%	0.361	35%	0.345	S	S	.	.	H	α-helix	trans	-70.5	-37	178.2	-171.2	51.7	172.9	169.3	0	112.7	N42 M43 A44 E49 L50 I107	N42-K46 PolarHBondContact O-N 3.16Å; M43-K46 PolarHBondContact O-N 3.17Å; A44-K46 VanDerWaalsContact C-N 3.33Å; A44-K46 PolarHBondContact O-N 3.43Å; K46-E49 WeakPolarHBondContact CD-OE2 3.34Å; K46-E49 IonicContact NZ-OE1 2.81Å; K46-E49 PolarHBondContact NZ-OE1 3.12Å; K46-E49 IonicContact NZ-OE2 2.82Å; K46-E49 PolarHBondContact NZ-OE2 3.35Å; K46-E49 PolarHBondContact O-N 3.41Å; K46-L50 HydrophobicContact CD-CG 4.47Å; K46-L50 HydrophobicContact CG-CD1 4.46Å; K46-L50 WeakPolarHBondContact O-CG 3.37Å; K46-L50 PolarHBondContact O-N 2.97Å; K46-L50 VanDerWaalsContact O-N 3.12Å; K46-I107 HydrophobicContact CG-CD1 4.17Å
47	A	97.8	Very high	97.4	Very high	4 Å²	4	69.8 Å²	69.8	3%	0.033	35%	0.351	C	S	.	.	H	α-helix	trans	-59.9	-48.1	173.5	0	0	0	0	0	110.8	M43 A44 E49 L50 E51 I107	M43-A47 PolarHBondContact O-N 3.33Å; A44-A47 PolarHBondContact O-N 3.42Å; A47-E49 VanDerWaalsContact C-N 3.34Å; A47-E49 PolarHBondContact O-N 3.2Å; A47-L50 PolarHBondContact O-N 3.48Å; A47-E51 WeakPolarHBondContact O-CG 3.41Å; A47-E51 PolarHBondContact O-N 3.11Å; A47-I107 HydrophobicContact CB-CG2 4Å
48	A	97.8	Very high	97.5	Very high	40 Å²	40	68 Å²	68	33%	0.331	35%	0.347	S	S	.	.	H	α-helix	trans	-61.3	-38.7	179	0	0	0	0	0	113.1	A44 S45 E51 M52	A44-A48 PolarHBondContact O-N 2.8Å; A44-A48 VanDerWaalsContact O-N 3.07Å; S45-A48 PolarHBondContact O-N 2.98Å; A48-E51 PolarHBondContact O-N 3.31Å; A48-M52 WeakPolarHBondContact O-CG 3.37Å; A48-M52 PolarHBondContact O-N 2.92Å
49	E	98.1	Very high	97.5	Very high	97 Å²	97	69.3 Å²	69.3	45%	0.453	36%	0.357	S	S	.	.	H	α-helix	trans	-60.4	-48.9	173.6	-172.2	-167	153.4	0	0	111.2	S45 K46 A47 E51 M52 D53	S45-E49 PolarHBondContact O-N 2.93Å; S45-E49 VanDerWaalsContact O-N 3.13Å; K46-E49 WeakPolarHBondContact CD-OE2 3.34Å; K46-E49 IonicContact NZ-OE1 2.81Å; K46-E49 PolarHBondContact NZ-OE1 3.12Å; K46-E49 IonicContact NZ-OE2 2.82Å; K46-E49 PolarHBondContact NZ-OE2 3.35Å; K46-E49 PolarHBondContact O-N 3.41Å; A47-E49 VanDerWaalsContact C-N 3.34Å; A47-E49 PolarHBondContact O-N 3.2Å; E49-E51 VanDerWaalsContact C-N 3.31Å; E49-E51 PolarHBondContact O-N 3.48Å; E49-M52 WeakPolarHBondContact O-CB 3.17Å; E49-M52 PolarHBondContact O-N 3.42Å; E49-M52 VanDerWaalsContact O-N 3.12Å; E49-D53 PolarHBondContact O-N 3.23Å; E49-D53 VanDerWaalsContact O-N 3.17Å
50	L	98.3	Very high	97.5	Very high	19 Å²	19	69.1 Å²	69.1	10%	0.099	36%	0.36	C	S	.	.	H	α-helix	trans	-67.7	-29.9	179.7	-66.6	177.2	0	0	0	112.8	K46 A47 M52 D53 I54 I100 V103 I104 I107	K46-L50 HydrophobicContact CD-CG 4.47Å; K46-L50 HydrophobicContact CG-CD1 4.46Å; K46-L50 WeakPolarHBondContact O-CG 3.37Å; K46-L50 PolarHBondContact O-N 2.97Å; K46-L50 VanDerWaalsContact O-N 3.12Å; A47-L50 PolarHBondContact O-N 3.48Å; L50-M52 VanDerWaalsContact C-N 3.31Å; L50-D53 PolarHBondContact O-N 3.01Å; L50-I54 PolarHBondContact O-N 3.4Å; L50-I100 HydrophobicContact CB-CG2 3.87Å; L50-I100 HydrophobicContact CD2-CG2 4.15Å; L50-I100 HydrophobicContact CG-CG2 4.45Å; L50-V103 HydrophobicContact CD1-CB 4.48Å; L50-V103 HydrophobicContact CD1-CG1 3.75Å; L50-I104 HydrophobicContact CB-CD1 3.74Å; L50-I104 HydrophobicContact CB-CG1 3.62Å; L50-I104 HydrophobicContact CD1-CG1 4.13Å; L50-I107 HydrophobicContact CD1-CD1 3.79Å
51	E	97.9	Very high	97.6	Very high	96 Å²	96	66.6 Å²	66.6	45%	0.449	35%	0.349	S	S	.	.	H	α-helix	trans	-64.3	-37	172	-74.7	175.5	174.7	0	0	111.5	A47 A48 E49 I54 N55 I104	A47-E51 WeakPolarHBondContact O-CG 3.41Å; A47-E51 PolarHBondContact O-N 3.11Å; A48-E51 PolarHBondContact O-N 3.31Å; E49-E51 VanDerWaalsContact C-N 3.31Å; E49-E51 PolarHBondContact O-N 3.48Å; E51-I54 PolarHBondContact O-N 3.23Å; E51-N55 PolarHBondContact O-N 2.98Å; E51-N55 PolarHBondContact O-ND2 3.46Å; E51-I104 HydrophobicContact CG-CD1 3.9Å
52	M	98.1	Very high	97.6	Very high	122 Å²	122	64.7 Å²	64.7	60%	0.601	35%	0.348	S	S	*	.	H	α-helix	trans	-63.7	-45.8	172.5	-64.3	178.1	-174.1	0	0	110.9	A48 E49 L50 I54 N55 E56	A48-M52 WeakPolarHBondContact O-CG 3.37Å; A48-M52 PolarHBondContact O-N 2.92Å; E49-M52 WeakPolarHBondContact O-CB 3.17Å; E49-M52 PolarHBondContact O-N 3.42Å; E49-M52 VanDerWaalsContact O-N 3.12Å; L50-M52 VanDerWaalsContact C-N 3.31Å; M52-I54 VanDerWaalsContact C-N 3.28Å; M52-I54 PolarHBondContact O-N 2.91Å; M52-N55 WeakPolarHBondContact O-CB 3.17Å; M52-N55 PolarHBondContact O-N 2.66Å; M52-E56 PolarHBondContact O-N 3.37Å
53	D	97.5	Very high	97.5	Very high	50 Å²	50	64.2 Å²	64.2	27%	0.267	35%	0.349	S	S	.	.	H	α-helix	trans	-57.4	-40.6	177	-66.6	-15	0	0	0	111.9	E49 L50 N55 E56 H57 I100	E49-D53 PolarHBondContact O-N 3.23Å; E49-D53 VanDerWaalsContact O-N 3.17Å; L50-D53 PolarHBondContact O-N 3.01Å; D53-N55 VanDerWaalsContact C-N 3.33Å; D53-N55 PolarHBondContact O-N 2.84Å; D53-E56 PolarHBondContact O-N 3.12Å; D53-H57 WeakPolarHBondContact O-CB 3.48Å; D53-H57 PolarHBondContact O-CD2 3.48Å; D53-H57 PolarHBondContact O-N 3.43Å; D53-I100 HydrophobicContact CB-CD1 4.35Å
54	I	98	Very high	97.4	Very high	25 Å²	25	64 Å²	64	13%	0.128	35%	0.348	C	S	.	.	H	α-helix	trans	-61.2	-41.9	175.4	-76	179.5	0	0	0	111.7	L50 E51 M52 H57 S58 K97 I100 S101 I104	L50-I54 PolarHBondContact O-N 3.4Å; E51-I54 PolarHBondContact O-N 3.23Å; M52-I54 VanDerWaalsContact C-N 3.28Å; M52-I54 PolarHBondContact O-N 2.91Å; I54-H57 PolarHBondContact O-N 3.13Å; I54-S58 WeakPolarHBondContact O-CB 3.4Å; I54-S58 PolarHBondContact O-N 2.97Å; I54-S58 PolarHBondContact O-OG 2.89Å; I54-K97 HydrophobicContact CG2-CG 4.39Å; I54-I100 HydrophobicContact CD1-CB 4.49Å; I54-I100 HydrophobicContact CD1-CG2 3.97Å; I54-I100 HydrophobicContact CG1-CB 4.15Å; I54-I100 HydrophobicContact CG1-CG2 3.67Å; I54-S101 WeakPolarHBondContact CD1-OG 3.35Å; I54-I104 HydrophobicContact CD1-CD1 3.37Å; I54-I104 HydrophobicContact CG1-CD1 4.28Å
55	N	97.5	Very high	97.3	Very high	108 Å²	108	67.5 Å²	67.5	58%	0.578	36%	0.355	S	S	*	.	H	α-helix	trans	-66	-43.3	-179.9	-68	-36.8	0	0	0	110.7	E51 M52 D53 S58 L59	E51-N55 PolarHBondContact O-N 2.98Å; E51-N55 PolarHBondContact O-ND2 3.46Å; M52-N55 WeakPolarHBondContact O-CB 3.17Å; M52-N55 PolarHBondContact O-N 2.66Å; D53-N55 VanDerWaalsContact C-N 3.33Å; D53-N55 PolarHBondContact O-N 2.84Å; N55-S58 WeakPolarHBondContact O-CB 3.31Å; N55-S58 PolarHBondContact O-N 3.07Å; N55-L59 PolarHBondContact O-N 3.47Å
56	E	97	Very high	97.2	Very high	128 Å²	128	72.3 Å²	72.3	60%	0.598	37%	0.369	S	S	*	.	H	α-helix	trans	-61.4	-48.4	174.7	-67.6	-175.5	175.7	0	0	111.7	M52 D53 S58 L59 V60	M52-E56 PolarHBondContact O-N 3.37Å; D53-E56 PolarHBondContact O-N 3.12Å; E56-S58 VanDerWaalsContact C-N 3.27Å; E56-S58 PolarHBondContact O-N 3.18Å; E56-L59 PolarHBondContact O-N 3.27Å; E56-V60 WeakPolarHBondContact O-CG2 3.44Å; E56-V60 PolarHBondContact O-N 3.28Å
57	H	97.3	Very high	97.1	Very high	45 Å²	45	71.2 Å²	71.2	21%	0.208	37%	0.369	C	S	.	.	H	α-helix	trans	-58.1	-40.5	175.4	-83.7	-59.1	0	0	0	112.1	D53 I54 V60 I61 L93 K97	D53-H57 WeakPolarHBondContact O-CB 3.48Å; D53-H57 PolarHBondContact O-CD2 3.48Å; D53-H57 PolarHBondContact O-N 3.43Å; I54-H57 PolarHBondContact O-N 3.13Å; H57-V60 PolarHBondContact O-N 2.98Å; H57-I61 WeakPolarHBondContact O-CB 3.4Å; H57-I61 WeakPolarHBondContact O-CD1 3.37Å; H57-I61 WeakPolarHBondContact O-CG1 3.49Å; H57-I61 PolarHBondContact O-N 3.38Å; H57-L93 WeakPolarHBondContact ND1-CD2 3.24Å; H57-K97 HydrophobicContact CB-CB 4.23Å
58	S	97.8	Very high	97.1	Very high	21 Å²	21	75.5 Å²	75.5	15%	0.147	39%	0.391	C	S	.	.	H	α-helix	trans	-62	-47.3	178.5	-58.7	0	0	0	0	111.5	I54 N55 E56 V60 I61 D62 K97	I54-S58 WeakPolarHBondContact O-CB 3.4Å; I54-S58 PolarHBondContact O-N 2.97Å; I54-S58 PolarHBondContact O-OG 2.89Å; N55-S58 WeakPolarHBondContact O-CB 3.31Å; N55-S58 PolarHBondContact O-N 3.07Å; E56-S58 VanDerWaalsContact C-N 3.27Å; E56-S58 PolarHBondContact O-N 3.18Å; S58-V60 VanDerWaalsContact C-N 3.34Å; S58-V60 PolarHBondContact O-N 3.42Å; S58-I61 PolarHBondContact O-N 2.83Å; S58-D62 VanDerWaalsContact O-CG 3.27Å; S58-D62 PolarHBondContact O-N 3.47Å; S58-K97 VanDerWaalsContact OG-CE 3.27Å; S58-K97 WeakPolarHBondContact OG-CE 3.37Å; S58-K97 PolarHBondContact OG-NZ 3.36Å
59	L	97.8	Very high	97	Very high	119 Å²	119	77.2 Å²	77.2	62%	0.623	40%	0.399	S	S	*	.	H	α-helix	trans	-60.1	-43.9	177.5	-178.9	62.7	0	0	0	111.9	N55 E56 D62 T63	N55-L59 PolarHBondContact O-N 3.47Å; E56-L59 PolarHBondContact O-N 3.27Å; L59-D62 PolarHBondContact O-N 2.97Å; L59-T63 WeakPolarHBondContact O-CG2 3.43Å; L59-T63 PolarHBondContact O-N 3.37Å; L59-T63 VanDerWaalsContact O-N 3.09Å; L59-T63 PolarHBondContact O-OG1 3.44Å
60	V	96.3	Very high	96.9	Very high	64 Å²	64	76.7 Å²	76.7	39%	0.388	41%	0.406	S	S	.	.	H	α-helix	trans	-65.9	-41.8	178.3	177.7	0	0	0	0	111.3	E56 H57 S58 T63 L64 L93	E56-V60 WeakPolarHBondContact O-CG2 3.44Å; E56-V60 PolarHBondContact O-N 3.28Å; H57-V60 PolarHBondContact O-N 2.98Å; S58-V60 VanDerWaalsContact C-N 3.34Å; S58-V60 PolarHBondContact O-N 3.42Å; V60-T63 PolarHBondContact O-OG1 2.82Å; V60-L64 HydrophobicContact CG1-CD1 3.86Å; V60-L64 HydrophobicContact CG1-CG 4.32Å; V60-L64 WeakPolarHBondContact O-CB 3.37Å; V60-L64 VanDerWaalsContact O-CG 3.31Å; V60-L64 WeakPolarHBondContact O-CG 3.39Å; V60-L64 PolarHBondContact O-N 3.33Å; V60-L93 HydrophobicContact CG1-CD1 3.72Å
61	I	97.3	Very high	96.9	Very high	6 Å²	6	84 Å²	84	3%	0.031	43%	0.432	C	S	.	.	H	α-helix	trans	-62	-46.6	177.3	-71.6	161.7	0	0	0	110.7	H57 S58 T63 L64 K65 L93 E94 K97	H57-I61 WeakPolarHBondContact O-CB 3.4Å; H57-I61 WeakPolarHBondContact O-CD1 3.37Å; H57-I61 WeakPolarHBondContact O-CG1 3.49Å; H57-I61 PolarHBondContact O-N 3.38Å; S58-I61 PolarHBondContact O-N 2.83Å; I61-T63 VanDerWaalsContact C-N 3.33Å; I61-T63 PolarHBondContact O-N 3.45Å; I61-L64 PolarHBondContact O-N 3.18Å; I61-K65 HydrophobicContact CG2-CD 4.19Å; I61-K65 VanDerWaalsContact CG2-CE 3.48Å; I61-K65 HydrophobicContact CG2-CG 4.44Å; I61-K65 WeakPolarHBondContact O-CG 3.41Å; I61-K65 PolarHBondContact O-N 3.05Å; I61-L93 HydrophobicContact CD1-CB 4.07Å; I61-L93 HydrophobicContact CG1-CB 3.73Å; I61-L93 HydrophobicContact CG1-CD1 4.41Å; I61-E94 HydrophobicContact CD1-CG 3.97Å; I61-E94 HydrophobicContact CG1-CG 4.33Å; I61-E94 HydrophobicContact CG2-CG 4.21Å; I61-K97 HydrophobicContact CD1-CB 4.39Å; I61-K97 HydrophobicContact CD1-CD 4.02Å
62	D	97.6	Very high	96.8	Very high	88 Å²	88	85 Å²	85	47%	0.471	44%	0.435	S	S	.	.	H	α-helix	trans	-64.2	-40.2	-177.1	-68.9	-20.2	0	0	0	111.5	S58 L59 K65	S58-D62 VanDerWaalsContact O-CG 3.27Å; S58-D62 PolarHBondContact O-N 3.47Å; L59-D62 PolarHBondContact O-N 2.97Å; D62-K65 IonicContact OD1-NZ 3.32Å
63	T	95.8	Very high	96.7	Very high	78 Å²	78	80.5 Å²	80.5	48%	0.479	42%	0.415	S	S	.	.	H	α-helix	trans	-66.7	-39	174	57.4	0	0	0	0	112.8	L59 V60 I61 V67	L59-T63 WeakPolarHBondContact O-CG2 3.43Å; L59-T63 PolarHBondContact O-N 3.37Å; L59-T63 VanDerWaalsContact O-N 3.09Å; L59-T63 PolarHBondContact O-OG1 3.44Å; V60-T63 PolarHBondContact O-OG1 2.82Å; I61-T63 VanDerWaalsContact C-N 3.33Å; I61-T63 PolarHBondContact O-N 3.45Å; T63-V67 WeakPolarHBondContact O-CG2 3.34Å
64	L	95.4	Very high	96.6	Very high	28 Å²	28	83.2 Å²	83.2	15%	0.147	43%	0.425	C	S	.	.	H	α-helix	trans	-75.3	-22.7	-178.7	-74	179.7	0	0	0	113.9	V60 I61 E66 V67 V86 V89 L90 L93	V60-L64 HydrophobicContact CG1-CD1 3.86Å; V60-L64 HydrophobicContact CG1-CG 4.32Å; V60-L64 WeakPolarHBondContact O-CB 3.37Å; V60-L64 VanDerWaalsContact O-CG 3.31Å; V60-L64 WeakPolarHBondContact O-CG 3.39Å; V60-L64 PolarHBondContact O-N 3.33Å; I61-L64 PolarHBondContact O-N 3.18Å; L64-E66 PolarHBondContact O-N 2.98Å; L64-V67 PolarHBondContact O-N 3.5Å; L64-V67 VanDerWaalsContact O-N 3.16Å; L64-V86 HydrophobicContact CB-CG1 4.48Å; L64-V86 HydrophobicContact CD2-CG2 4.28Å; L64-V89 HydrophobicContact CD1-CG1 4.38Å; L64-L90 HydrophobicContact CB-CD1 3.51Å; L64-L93 HydrophobicContact CD1-CD1 3.69Å
65	K	94.9	Very high	96.3	Very high	118 Å²	118	88.6 Å²	88.6	51%	0.513	44%	0.444	S	S	.	.	H	α-helix	trans	-63.2	-29.2	175.6	-80.9	171.5	179.7	163.8	0	113.1	I61 D62 V67 L90	I61-K65 HydrophobicContact CG2-CD 4.19Å; I61-K65 VanDerWaalsContact CG2-CE 3.48Å; I61-K65 HydrophobicContact CG2-CG 4.44Å; I61-K65 WeakPolarHBondContact O-CG 3.41Å; I61-K65 PolarHBondContact O-N 3.05Å; D62-K65 IonicContact OD1-NZ 3.32Å; K65-V67 VanDerWaalsContact C-N 3.31Å; K65-L90 HydrophobicContact CG-CD1 4.15Å; K65-L90 HydrophobicContact CG-CD2 4.39Å
66	E	94.8	Very high	96	Very high	180 Å²	180	89.1 Å²	89.1	84%	0.841	45%	0.446	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.5	-6.4	178.7	-59.1	-175.7	168.9	0	0	112.7	L64	L64-E66 PolarHBondContact O-N 2.98Å
67	V	96.2	Very high	95.8	Very high	59 Å²	59	86 Å²	86	36%	0.358	44%	0.435	S	S	.	.	S	Bend	trans	-94.1	145.3	-177.4	-178.6	0	0	0	0	110.6	T63 L64 K65 R71 V86	T63-V67 WeakPolarHBondContact O-CG2 3.34Å; L64-V67 PolarHBondContact O-N 3.5Å; L64-V67 VanDerWaalsContact O-N 3.16Å; K65-V67 VanDerWaalsContact C-N 3.31Å; V67-R71 HydrophobicContact CG1-CB 4.02Å; V67-R71 HydrophobicContact CG1-CG 4.18Å; V67-V86 HydrophobicContact CG1-CG2 4.02Å
68	D	96.9	Very high	95.6	Very high	94 Å²	94	88.2 Å²	88.2	50%	0.503	47%	0.47	S	S	.	.			trans	-53.5	125.7	175.4	-175.3	-69.1	0	0	0	111.8	S70 R71	D68-S70 PolarHBondContact O-N 3.06Å; D68-S70 VanDerWaalsContact O-N 3.16Å; D68-S70 WeakPolarHBondContact OD1-CA 3.36Å; D68-S70 VanDerWaalsContact OD1-CB 3.26Å; D68-S70 WeakPolarHBondContact OD1-CB 3.49Å; D68-S70 PolarHBondContact OD1-N 3.18Å; D68-S70 PolarHBondContact OD1-OG 3.2Å; D68-R71 HydrophobicContact CB-CB 4.38Å; D68-R71 WeakPolarHBondContact O-CB 3.46Å; D68-R71 PolarHBondContact O-N 3.36Å; D68-R71 PolarHBondContact OD1-N 2.96Å
69	P	96.4	Very high	95.5	Very high	77 Å²	77	90.3 Å²	90.3	50%	0.5	50%	0.495	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.4	-25.2	-176.8	-25.5	34.2	0	0	0	115.1	R71 V86 K87	P69-R71 VanDerWaalsContact C-N 3.35Å; P69-V86 PolarHBondContact O-N 3.4Å; P69-K87 HydrophobicContact CB-CB 4Å; P69-K87 WeakPolarHBondContact O-CB 3.43Å; P69-K87 WeakPolarHBondContact O-CG 3.49Å; P69-K87 PolarHBondContact O-N 3.1Å
70	S	96.6	Very high	95.4	Very high	86 Å²	86	89.3 Å²	89.3	60%	0.601	49%	0.494	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.1	-9.9	178	76.3	0	0	0	0	113.2	D68	D68-S70 PolarHBondContact O-N 3.06Å; D68-S70 VanDerWaalsContact O-N 3.16Å; D68-S70 WeakPolarHBondContact OD1-CA 3.36Å; D68-S70 VanDerWaalsContact OD1-CB 3.26Å; D68-S70 WeakPolarHBondContact OD1-CB 3.49Å; D68-S70 PolarHBondContact OD1-N 3.18Å; D68-S70 PolarHBondContact OD1-OG 3.2Å
71	R	97.2	Very high	95.4	Very high	171 Å²	171	91.6 Å²	91.6	65%	0.645	50%	0.503	S	S	*	.	S	Bend	trans	-61.2	138.2	177.8	-168.6	66.5	176.5	163.4	-0.5	110.4	V67 D68 P69 T85 V86	V67-R71 HydrophobicContact CG1-CB 4.02Å; V67-R71 HydrophobicContact CG1-CG 4.18Å; D68-R71 HydrophobicContact CB-CB 4.38Å; D68-R71 WeakPolarHBondContact O-CB 3.46Å; D68-R71 PolarHBondContact O-N 3.36Å; D68-R71 PolarHBondContact OD1-N 2.96Å; P69-R71 VanDerWaalsContact C-N 3.35Å; R71-T85 WeakPolarHBondContact O-CA 3.35Å; R71-V86 HydrophobicContact CB-CG2 4.16Å; R71-V86 PolarHBondContact O-N 3.25Å
72	K	96.9	Very high	95.3	Very high	119 Å²	119	93.6 Å²	93.6	52%	0.517	52%	0.516	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-65.6	135.1	174.1	-63.4	-175.9	175.1	-148.5	0	110.4	F74 E83 R84	K72-F74 HydrophobicContact CB-CE2 4.12Å; K72-F74 HydrophobicContact CB-CZ 4.31Å; K72-F74 HydrophobicContact CD-CZ 4.46Å; K72-E83 HydrophobicContact CD-CG 4.4Å; K72-E83 VanDerWaalsContact CD-OE1 3.25Å; K72-E83 WeakPolarHBondContact CD-OE1 3.24Å; K72-E83 WeakPolarHBondContact CE-OE1 3.37Å; K72-E83 IonicContact NZ-OE1 2.66Å; K72-E83 PolarHBondContact NZ-OE1 3.11Å; K72-E83 IonicContact NZ-OE2 3.62Å; K72-E83 PolarHBondContact NZ-OE2 2.88Å; K72-R84 CarbonylContact C-O 3.56Å; K72-R84 WeakPolarHBondContact CA-O 3.46Å
73	C	95.7	Very high	95.2	Very high	26 Å²	26	94.3 Å²	94.3	18%	0.176	52%	0.516	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.2	144	174.3	-176.4	0	0	0	0	108.2	R84 V86 V89	C73-R84 PolarHBondContact N-O 2.96Å; C73-R84 CarbonylContact O-C 3.57Å; C73-R84 PolarHBondContact O-N 2.96Å; C73-V86 HydrophobicContact CB-CG2 4.47Å; C73-V89 HydrophobicContact CB-CG2 4.05Å
74	F	95.1	Very high	95.2	Very high	108 Å²	108	96.1 Å²	96.1	47%	0.474	51%	0.514	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.6	126.5	-179.8	-62.1	-88.4	0	0	0	109.7	K72 L81 V82 E83	K72-F74 HydrophobicContact CB-CE2 4.12Å; K72-F74 HydrophobicContact CB-CZ 4.31Å; K72-F74 HydrophobicContact CD-CZ 4.46Å; F74-L81 HydrophobicContact CB-CD2 4.24Å; F74-V82 WeakPolarHBondContact CA-O 3.33Å; F74-E83 HydrophobicContact CD1-CB 4.01Å; F74-E83 HydrophobicContact CD1-CG 4.3Å; F74-E83 HydrophobicContact CE1-CB 3.71Å; F74-E83 HydrophobicContact CE1-CG 3.69Å; F74-E83 HydrophobicContact CZ-CG 4.13Å
75	R	91.6	Very high	95.3	Very high	138 Å²	138	96 Å²	96	52%	0.521	52%	0.515	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-108.7	127.1	175.8	-175.8	177.7	65.6	114.8	-0.7	109.8	V77 V82	R75-V77 HydrophobicContact CG-CG2 4.17Å; R75-V82 PolarHBondContact N-O 3.41Å; R75-V82 PolarHBondContact O-N 3.03Å
76	L	91.9	Very high	95.4	Very high	118 Å²	118	90.8 Å²	90.8	62%	0.618	49%	0.493	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-78.8	125.7	174	-172.5	66.2	0	0	0	110.3	L81	L76-L81 HydrophobicContact CB-CD2 4Å; L76-L81 HydrophobicContact CD1-CD2 3.92Å; L76-L81 HydrophobicContact CD1-CG 4.25Å
77	V	92.3	Very high	95.5	Very high	63 Å²	63	88.5 Å²	88.5	38%	0.382	48%	0.48	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-136.2	114.8	176.3	-174.2	0	0	0	0	108.5	R75 G79 V80 V82	R75-V77 HydrophobicContact CG-CG2 4.17Å; V77-G79 PolarHBondContact O-N 2.82Å; V77-G79 VanDerWaalsContact O-N 3.11Å; V77-V80 PolarHBondContact N-O 2.86Å; V77-V80 PolarHBondContact O-N 3.26Å; V77-V82 HydrophobicContact CG2-CG2 4.22Å
78	G	93.6	Very high	95.4	Very high	91 Å²	91	90.1 Å²	90.1	94%	0.938	48%	0.484	S	S	*	.	T	Hydrogen-bonded Turn	trans	55.4	31.5	177.3	0	0	0	0	0	114.3
79	G	94.9	Very high	95.3	Very high	66 Å²	66	86.8 Å²	86.8	68%	0.68	47%	0.467	S	S	*	.	T	Hydrogen-bonded Turn	trans	89.1	-3.7	-177.7	0	0	0	0	0	115.6	V77	V77-G79 PolarHBondContact O-N 2.82Å; V77-G79 VanDerWaalsContact O-N 3.11Å
80	V	95.9	Very high	95.3	Very high	98 Å²	98	84.6 Å²	84.6	59%	0.594	45%	0.451	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-107.3	134.5	176.8	-177.4	0	0	0	0	110.4	V77	V77-V80 PolarHBondContact N-O 2.86Å; V77-V80 PolarHBondContact O-N 3.26Å
81	L	95.9	Very high	95.3	Very high	111 Å²	111	83.8 Å²	83.8	58%	0.581	44%	0.444	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-84.2	120.3	172.5	-70.5	173.2	0	0	0	110.3	F74 L76	F74-L81 HydrophobicContact CB-CD2 4.24Å; L76-L81 HydrophobicContact CB-CD2 4Å; L76-L81 HydrophobicContact CD1-CD2 3.92Å; L76-L81 HydrophobicContact CD1-CG 4.25Å
82	V	95.7	Very high	95.2	Very high	49 Å²	49	78 Å²	78	30%	0.297	43%	0.432	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-97.3	119.4	175.3	-176.9	0	0	0	0	108.9	F74 R75 V77	F74-V82 WeakPolarHBondContact CA-O 3.33Å; R75-V82 PolarHBondContact N-O 3.41Å; R75-V82 PolarHBondContact O-N 3.03Å; V77-V82 HydrophobicContact CG2-CG2 4.22Å
83	E	96	Very high	95.2	Very high	103 Å²	103	73.6 Å²	73.6	48%	0.481	41%	0.414	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-73	133	174.1	-171.1	176.5	139.8	0	0	110.9	K72 F74	K72-E83 HydrophobicContact CD-CG 4.4Å; K72-E83 VanDerWaalsContact CD-OE1 3.25Å; K72-E83 WeakPolarHBondContact CD-OE1 3.24Å; K72-E83 WeakPolarHBondContact CE-OE1 3.37Å; K72-E83 IonicContact NZ-OE1 2.66Å; K72-E83 PolarHBondContact NZ-OE1 3.11Å; K72-E83 IonicContact NZ-OE2 3.62Å; K72-E83 PolarHBondContact NZ-OE2 2.88Å; F74-E83 HydrophobicContact CD1-CB 4.01Å; F74-E83 HydrophobicContact CD1-CG 4.3Å; F74-E83 HydrophobicContact CE1-CB 3.71Å; F74-E83 HydrophobicContact CE1-CG 3.69Å; F74-E83 HydrophobicContact CZ-CG 4.13Å
84	R	95.8	Very high	95.2	Very high	115 Å²	115	76.2 Å²	76.2	43%	0.434	42%	0.424	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-143.1	-179.2	175.1	-71	-73.1	-179.5	127.4	-3.1	108.6	K72 C73 E88 V89	K72-R84 CarbonylContact C-O 3.56Å; K72-R84 WeakPolarHBondContact CA-O 3.46Å; C73-R84 PolarHBondContact N-O 2.96Å; C73-R84 CarbonylContact O-C 3.57Å; C73-R84 PolarHBondContact O-N 2.96Å; R84-E88 WeakPolarHBondContact CD-OE2 3.48Å; R84-V89 HydrophobicContact CB-CG2 3.57Å; R84-V89 HydrophobicContact CG-CG2 4.18Å
85	T	97.3	Very high	95.4	Very high	27 Å²	27	74.7 Å²	74.7	17%	0.166	42%	0.42	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.3	158.6	167.8	51.8	0	0	0	0	111.7	R71 K87 E88 V89	R71-T85 WeakPolarHBondContact O-CA 3.35Å; T85-K87 PolarHBondContact O-N 3.42Å; T85-K87 VanDerWaalsContact OG1-CE 3.31Å; T85-K87 WeakPolarHBondContact OG1-CE 3.41Å; T85-K87 WeakPolarHBondContact OG1-CG 3.34Å; T85-E88 PolarHBondContact N-OE2 3.22Å; T85-E88 PolarHBondContact O-N 2.84Å; T85-E88 WeakPolarHBondContact OG1-CG 3.47Å; T85-E88 PolarHBondContact OG1-OE2 3.33Å; T85-E88 VanDerWaalsContact OG1-OE2 3.12Å; T85-V89 WeakPolarHBondContact O-CG2 3.27Å; T85-V89 PolarHBondContact O-N 3.37Å
86	V	96.7	Very high	95.6	Very high	7 Å²	7	71.5 Å²	71.5	4%	0.042	41%	0.414	C	S	.	.	H	α-helix	trans	-55.9	-41.7	176.9	172.6	0	0	0	0	111.1	L64 V67 P69 R71 C73 E88 V89 L90	L64-V86 HydrophobicContact CB-CG1 4.48Å; L64-V86 HydrophobicContact CD2-CG2 4.28Å; V67-V86 HydrophobicContact CG1-CG2 4.02Å; P69-V86 PolarHBondContact O-N 3.4Å; R71-V86 HydrophobicContact CB-CG2 4.16Å; R71-V86 PolarHBondContact O-N 3.25Å; C73-V86 HydrophobicContact CB-CG2 4.47Å; V86-E88 PolarHBondContact O-N 2.95Å; V86-E88 VanDerWaalsContact O-N 3.14Å; V86-V89 PolarHBondContact O-N 2.82Å; V86-V89 VanDerWaalsContact O-N 3.14Å; V86-L90 WeakPolarHBondContact O-CB 3.38Å; V86-L90 PolarHBondContact O-N 3.35Å
87	K	96.3	Very high	95.9	Very high	132 Å²	132	69.1 Å²	69.1	57%	0.574	40%	0.399	S	S	*	.	H	α-helix	trans	-58.5	-24.6	175.7	65.7	176.7	-176	178.6	0	114.6	P69 T85 P91	P69-K87 HydrophobicContact CB-CB 4Å; P69-K87 WeakPolarHBondContact O-CB 3.43Å; P69-K87 WeakPolarHBondContact O-CG 3.49Å; P69-K87 PolarHBondContact O-N 3.1Å; T85-K87 PolarHBondContact O-N 3.42Å; T85-K87 VanDerWaalsContact OG1-CE 3.31Å; T85-K87 WeakPolarHBondContact OG1-CE 3.41Å; T85-K87 WeakPolarHBondContact OG1-CG 3.34Å; K87-P91 VanDerWaalsContact O-CD 3.24Å; K87-P91 WeakPolarHBondContact O-CD 3.18Å; K87-P91 WeakPolarHBondContact O-CG 3.38Å
88	E	94.6	Very high	96.2	Very high	93 Å²	93	70.8 Å²	70.8	44%	0.435	40%	0.402	S	S	.	.	H	α-helix	trans	-92.2	-32	177.4	-68.3	165.8	161.2	0	0	112	R84 T85 V86	R84-E88 WeakPolarHBondContact CD-OE2 3.48Å; T85-E88 PolarHBondContact N-OE2 3.22Å; T85-E88 PolarHBondContact O-N 2.84Å; T85-E88 WeakPolarHBondContact OG1-CG 3.47Å; T85-E88 PolarHBondContact OG1-OE2 3.33Å; T85-E88 VanDerWaalsContact OG1-OE2 3.12Å; V86-E88 PolarHBondContact O-N 2.95Å; V86-E88 VanDerWaalsContact O-N 3.14Å
89	V	95.3	Very high	96.4	Very high	24 Å²	24	71.5 Å²	71.5	15%	0.145	38%	0.381	C	S	.	.	H	α-helix	trans	-83.4	-40.3	-175.5	174.1	0	0	0	0	111.7	L64 C73 R84 T85 V86 A92 L93	L64-V89 HydrophobicContact CD1-CG1 4.38Å; C73-V89 HydrophobicContact CB-CG2 4.05Å; R84-V89 HydrophobicContact CB-CG2 3.57Å; R84-V89 HydrophobicContact CG-CG2 4.18Å; T85-V89 WeakPolarHBondContact O-CG2 3.27Å; T85-V89 PolarHBondContact O-N 3.37Å; V86-V89 PolarHBondContact O-N 2.82Å; V86-V89 VanDerWaalsContact O-N 3.14Å; V89-A92 WeakPolarHBondContact O-CB 3.39Å; V89-A92 PolarHBondContact O-N 2.81Å; V89-A92 VanDerWaalsContact O-N 3.16Å; V89-L93 HydrophobicContact CG1-CD1 3.79Å; V89-L93 HydrophobicContact CG1-CG 4.08Å; V89-L93 PolarHBondContact O-N 3.05Å
90	L	95.9	Very high	96.5	Very high	32 Å²	32	69.7 Å²	69.7	17%	0.168	36%	0.356	C	S	.	.	H	α-helix	trans	-57.3	-49.7	-176.9	-161	104.9	0	0	0	112.3	L64 K65 V86 A92 L93 E94	L64-L90 HydrophobicContact CB-CD1 3.51Å; K65-L90 HydrophobicContact CG-CD1 4.15Å; K65-L90 HydrophobicContact CG-CD2 4.39Å; V86-L90 WeakPolarHBondContact O-CB 3.38Å; V86-L90 PolarHBondContact O-N 3.35Å; L90-A92 VanDerWaalsContact C-N 3.27Å; L90-A92 PolarHBondContact O-N 3Å; L90-L93 PolarHBondContact O-N 3.2Å; L90-E94 WeakPolarHBondContact O-CG 3.48Å; L90-E94 PolarHBondContact O-N 3.19Å
91	P	96.4	Very high	96.6	Very high	69 Å²	69	66.9 Å²	66.9	45%	0.448	34%	0.34	S	S	.	.	H	α-helix	trans	-65.5	-31.3	179.3	-19.6	33.9	0	0	0	112.7	K87 N95	K87-P91 VanDerWaalsContact O-CD 3.24Å; K87-P91 WeakPolarHBondContact O-CD 3.18Å; K87-P91 WeakPolarHBondContact O-CG 3.38Å; P91-N95 WeakPolarHBondContact O-CB 3.49Å; P91-N95 PolarHBondContact O-N 3.39Å
92	A	95.1	Very high	96.8	Very high	49 Å²	49	66.6 Å²	66.6	41%	0.405	33%	0.334	S	S	.	.	H	α-helix	trans	-69.2	-39.7	177	0	0	0	0	0	111.7	V89 L90 N96	V89-A92 WeakPolarHBondContact O-CB 3.39Å; V89-A92 PolarHBondContact O-N 2.81Å; V89-A92 VanDerWaalsContact O-N 3.16Å; L90-A92 VanDerWaalsContact C-N 3.27Å; L90-A92 PolarHBondContact O-N 3Å; A92-N96 WeakPolarHBondContact O-CB 3.33Å; A92-N96 PolarHBondContact O-N 2.91Å; A92-N96 PolarHBondContact O-ND2 3.35Å
93	L	96.3	Very high	96.9	Very high	26 Å²	26	67.7 Å²	67.7	14%	0.136	34%	0.341	C	S	.	.	H	α-helix	trans	-65.2	-43.7	174.6	-70.7	171	0	0	0	111.7	H57 V60 I61 L64 V89 L90 N96 K97	H57-L93 WeakPolarHBondContact ND1-CD2 3.24Å; V60-L93 HydrophobicContact CG1-CD1 3.72Å; I61-L93 HydrophobicContact CD1-CB 4.07Å; I61-L93 HydrophobicContact CG1-CB 3.73Å; I61-L93 HydrophobicContact CG1-CD1 4.41Å; L64-L93 HydrophobicContact CD1-CD1 3.69Å; V89-L93 HydrophobicContact CG1-CD1 3.79Å; V89-L93 HydrophobicContact CG1-CG 4.08Å; V89-L93 PolarHBondContact O-N 3.05Å; L90-L93 PolarHBondContact O-N 3.2Å; L93-N96 PolarHBondContact O-N 3.05Å; L93-K97 WeakPolarHBondContact O-CB 3.36Å; L93-K97 PolarHBondContact O-N 3.15Å
94	E	97.4	Very high	97	Very high	82 Å²	82	63.3 Å²	63.3	38%	0.383	32%	0.321	S	S	.	.	H	α-helix	trans	-61.9	-45.3	177	-71.3	178.9	159.4	0	0	111.7	I61 L90 K97 E98	I61-E94 HydrophobicContact CD1-CG 3.97Å; I61-E94 HydrophobicContact CG1-CG 4.33Å; I61-E94 HydrophobicContact CG2-CG 4.21Å; L90-E94 WeakPolarHBondContact O-CG 3.48Å; L90-E94 PolarHBondContact O-N 3.19Å; E94-K97 PolarHBondContact O-N 3.5Å; E94-E98 PolarHBondContact O-N 3.26Å
95	N	97.9	Very high	97.1	Very high	75 Å²	75	63.8 Å²	63.8	40%	0.401	33%	0.327	S	S	.	.	H	α-helix	trans	-62.9	-45.1	177	-166.8	-77.6	0	0	0	111.9	P91 K97 E98 Q99	P91-N95 WeakPolarHBondContact O-CB 3.49Å; P91-N95 PolarHBondContact O-N 3.39Å; N95-K97 PolarHBondContact O-N 3.47Å; N95-E98 PolarHBondContact O-N 2.94Å; N95-Q99 WeakPolarHBondContact O-CG 3.25Å; N95-Q99 PolarHBondContact O-N 3.11Å; N95-Q99 PolarHBondContact OD1-NE2 3.26Å
96	N	96.8	Very high	97.1	Very high	71 Å²	71	66 Å²	66	38%	0.38	34%	0.341	S	S	.	.	H	α-helix	trans	-61.9	-44.6	178	-72	-16.1	0	0	0	111.4	A92 L93 E98 Q99 I100	A92-N96 WeakPolarHBondContact O-CB 3.33Å; A92-N96 PolarHBondContact O-N 2.91Å; A92-N96 PolarHBondContact O-ND2 3.35Å; L93-N96 PolarHBondContact O-N 3.05Å; N96-E98 VanDerWaalsContact C-N 3.32Å; N96-E98 PolarHBondContact O-N 2.88Å; N96-Q99 PolarHBondContact O-N 2.81Å; N96-I100 VanDerWaalsContact O-CG1 3.27Å; N96-I100 WeakPolarHBondContact O-CG1 3.48Å; N96-I100 PolarHBondContact O-N 3.44Å
97	K	97.8	Very high	97.2	Very high	69 Å²	69	66.6 Å²	66.6	30%	0.3	34%	0.344	S	S	.	.	H	α-helix	trans	-56.4	-47	174.6	177.5	-178.7	164.7	176.6	0	111	I54 H57 S58 I61 L93 E94 N95 Q99 I100 S101	I54-K97 HydrophobicContact CG2-CG 4.39Å; H57-K97 HydrophobicContact CB-CB 4.23Å; S58-K97 VanDerWaalsContact OG-CE 3.27Å; S58-K97 WeakPolarHBondContact OG-CE 3.37Å; S58-K97 PolarHBondContact OG-NZ 3.36Å; I61-K97 HydrophobicContact CD1-CB 4.39Å; I61-K97 HydrophobicContact CD1-CD 4.02Å; L93-K97 WeakPolarHBondContact O-CB 3.36Å; L93-K97 PolarHBondContact O-N 3.15Å; E94-K97 PolarHBondContact O-N 3.5Å; N95-K97 PolarHBondContact O-N 3.47Å; K97-Q99 PolarHBondContact O-N 2.79Å; K97-I100 PolarHBondContact O-N 2.86Å; K97-S101 PolarHBondContact O-N 2.93Å; K97-S101 PolarHBondContact O-OG 3.26Å; K97-S101 VanDerWaalsContact O-OG 3.12Å
98	E	98.2	Very high	97.2	Very high	97 Å²	97	62.8 Å²	62.8	45%	0.453	33%	0.33	S	S	.	.	H	α-helix	trans	-61.9	-42.1	178.1	-168.1	-165.6	155.7	0	0	112.2	E94 N95 N96 S101 K102	E94-E98 PolarHBondContact O-N 3.26Å; N95-E98 PolarHBondContact O-N 2.94Å; N96-E98 VanDerWaalsContact C-N 3.32Å; N96-E98 PolarHBondContact O-N 2.88Å; E98-S101 WeakPolarHBondContact O-CB 3.44Å; E98-S101 PolarHBondContact O-N 2.71Å; E98-K102 WeakPolarHBondContact O-CG 3.39Å; E98-K102 PolarHBondContact O-N 2.98Å; E98-K102 VanDerWaalsContact O-N 3.11Å; E98-K102 VanDerWaalsContact OE1-CE 3.24Å; E98-K102 WeakPolarHBondContact OE1-CE 3.41Å; E98-K102 IonicContact OE1-NZ 2.69Å; E98-K102 PolarHBondContact OE1-NZ 3.42Å
99	Q	98.2	Very high	97.4	Very high	107 Å²	107	62.8 Å²	62.8	50%	0.5	34%	0.336	S	S	.	.	H	α-helix	trans	-62.5	-44	176	-70.9	-179.5	1.6	0	0	111.6	N95 N96 K97 S101 K102 V103	N95-Q99 WeakPolarHBondContact O-CG 3.25Å; N95-Q99 PolarHBondContact O-N 3.11Å; N95-Q99 PolarHBondContact OD1-NE2 3.26Å; N96-Q99 PolarHBondContact O-N 2.81Å; K97-Q99 PolarHBondContact O-N 2.79Å; Q99-S101 VanDerWaalsContact C-N 3.34Å; Q99-S101 PolarHBondContact O-N 3.42Å; Q99-K102 PolarHBondContact O-N 3.03Å; Q99-V103 WeakPolarHBondContact O-CG2 3.4Å; Q99-V103 PolarHBondContact O-N 3.43Å
100	I	97.9	Very high	97.5	Very high	28 Å²	28	66.7 Å²	66.7	14%	0.144	35%	0.353	C	S	.	.	H	α-helix	trans	-61.6	-43.4	176.8	-64.9	165.4	0	0	0	110.2	L50 D53 I54 N96 K97 K102 V103 I104	L50-I100 HydrophobicContact CB-CG2 3.87Å; L50-I100 HydrophobicContact CD2-CG2 4.15Å; L50-I100 HydrophobicContact CG-CG2 4.45Å; D53-I100 HydrophobicContact CB-CD1 4.35Å; I54-I100 HydrophobicContact CD1-CB 4.49Å; I54-I100 HydrophobicContact CD1-CG2 3.97Å; I54-I100 HydrophobicContact CG1-CB 4.15Å; I54-I100 HydrophobicContact CG1-CG2 3.67Å; N96-I100 VanDerWaalsContact O-CG1 3.27Å; N96-I100 WeakPolarHBondContact O-CG1 3.48Å; N96-I100 PolarHBondContact O-N 3.44Å; K97-I100 PolarHBondContact O-N 2.86Å; I100-K102 VanDerWaalsContact C-N 3.33Å; I100-K102 PolarHBondContact O-N 3.48Å; I100-V103 WeakPolarHBondContact O-CB 3.48Å; I100-V103 PolarHBondContact O-N 3.24Å; I100-V103 VanDerWaalsContact O-N 3.1Å; I100-I104 HydrophobicContact CG2-CD1 4.11Å; I100-I104 WeakPolarHBondContact O-CG1 3.42Å; I100-I104 PolarHBondContact O-N 2.89Å
101	S	97.9	Very high	97.5	Very high	38 Å²	38	67.3 Å²	67.3	27%	0.266	36%	0.356	S	S	.	.	H	α-helix	trans	-55.9	-45.7	175.4	-61	0	0	0	0	112.3	I54 K97 E98 Q99 V103 I104 E105	I54-S101 WeakPolarHBondContact CD1-OG 3.35Å; K97-S101 PolarHBondContact O-N 2.93Å; K97-S101 PolarHBondContact O-OG 3.26Å; K97-S101 VanDerWaalsContact O-OG 3.12Å; E98-S101 WeakPolarHBondContact O-CB 3.44Å; E98-S101 PolarHBondContact O-N 2.71Å; Q99-S101 VanDerWaalsContact C-N 3.34Å; Q99-S101 PolarHBondContact O-N 3.42Å; S101-V103 VanDerWaalsContact C-N 3.31Å; S101-V103 PolarHBondContact O-N 2.85Å; S101-I104 PolarHBondContact O-N 3.13Å; S101-E105 WeakPolarHBondContact O-CG 3.35Å; S101-E105 PolarHBondContact O-N 3.35Å
102	K	98.2	Very high	97.5	Very high	106 Å²	106	69.6 Å²	69.6	46%	0.461	36%	0.36	S	S	.	.	H	α-helix	trans	-63.4	-36.2	177.5	-70.2	172.9	-175.3	168.1	0	112.5	E98 Q99 I100 E105 T106	E98-K102 WeakPolarHBondContact O-CG 3.39Å; E98-K102 PolarHBondContact O-N 2.98Å; E98-K102 VanDerWaalsContact O-N 3.11Å; E98-K102 VanDerWaalsContact OE1-CE 3.24Å; E98-K102 WeakPolarHBondContact OE1-CE 3.41Å; E98-K102 IonicContact OE1-NZ 2.69Å; E98-K102 PolarHBondContact OE1-NZ 3.42Å; Q99-K102 PolarHBondContact O-N 3.03Å; I100-K102 VanDerWaalsContact C-N 3.33Å; I100-K102 PolarHBondContact O-N 3.48Å; K102-E105 PolarHBondContact O-N 3.3Å; K102-T106 PolarHBondContact O-N 3.34Å; K102-T106 PolarHBondContact O-OG1 2.87Å
103	V	98.1	Very high	97.6	Very high	71 Å²	71	69.4 Å²	69.4	43%	0.43	36%	0.358	S	S	.	.	H	α-helix	trans	-66	-42.8	175.2	174.2	0	0	0	0	110.5	L50 Q99 I100 S101 T106 I107	L50-V103 HydrophobicContact CD1-CB 4.48Å; L50-V103 HydrophobicContact CD1-CG1 3.75Å; Q99-V103 WeakPolarHBondContact O-CG2 3.4Å; Q99-V103 PolarHBondContact O-N 3.43Å; I100-V103 WeakPolarHBondContact O-CB 3.48Å; I100-V103 PolarHBondContact O-N 3.24Å; I100-V103 VanDerWaalsContact O-N 3.1Å; S101-V103 VanDerWaalsContact C-N 3.31Å; S101-V103 PolarHBondContact O-N 2.85Å; V103-T106 WeakPolarHBondContact O-CB 3.28Å; V103-T106 PolarHBondContact O-N 3.02Å; V103-I107 HydrophobicContact CG1-CD1 3.92Å; V103-I107 HydrophobicContact CG1-CG1 4.41Å; V103-I107 WeakPolarHBondContact O-CG1 3.39Å; V103-I107 PolarHBondContact O-N 3.2Å
104	I	98.1	Very high	97.7	Very high	12 Å²	12	69.8 Å²	69.8	6%	0.062	36%	0.359	C	S	.	.	H	α-helix	trans	-61.3	-45.1	175.8	-66.8	167.5	0	0	0	111.1	L50 E51 I54 I100 S101 T106 I107 N108	L50-I104 HydrophobicContact CB-CD1 3.74Å; L50-I104 HydrophobicContact CB-CG1 3.62Å; L50-I104 HydrophobicContact CD1-CG1 4.13Å; E51-I104 HydrophobicContact CG-CD1 3.9Å; I54-I104 HydrophobicContact CD1-CD1 3.37Å; I54-I104 HydrophobicContact CG1-CD1 4.28Å; I100-I104 HydrophobicContact CG2-CD1 4.11Å; I100-I104 WeakPolarHBondContact O-CG1 3.42Å; I100-I104 PolarHBondContact O-N 2.89Å; S101-I104 PolarHBondContact O-N 3.13Å; I104-T106 VanDerWaalsContact C-N 3.25Å; I104-T106 PolarHBondContact O-N 2.92Å; I104-I107 PolarHBondContact O-N 2.94Å; I104-N108 WeakPolarHBondContact O-CB 3.43Å; I104-N108 PolarHBondContact O-N 3.37Å; I104-N108 PolarHBondContact O-ND2 3.47Å
105	E	98.2	Very high	97.6	Very high	124 Å²	124	66.7 Å²	66.7	58%	0.579	35%	0.349	S	S	*	.	H	α-helix	trans	-57.2	-41	174.9	-72.3	174.3	-174.2	0	0	112	S101 K102 N108 T109	S101-E105 WeakPolarHBondContact O-CG 3.35Å; S101-E105 PolarHBondContact O-N 3.35Å; K102-E105 PolarHBondContact O-N 3.3Å; E105-N108 PolarHBondContact O-N 2.96Å; E105-T109 PolarHBondContact O-N 3.3Å; E105-T109 PolarHBondContact O-OG1 3.41Å
106	T	98.2	Very high	97.5	Very high	74 Å²	74	71 Å²	71	45%	0.454	36%	0.36	S	S	.	.	H	α-helix	trans	-64.8	-46.4	176.2	-56.4	0	0	0	0	111.3	K102 V103 I104 N108 T109 Q110	K102-T106 PolarHBondContact O-N 3.34Å; K102-T106 PolarHBondContact O-OG1 2.87Å; V103-T106 WeakPolarHBondContact O-CB 3.28Å; V103-T106 PolarHBondContact O-N 3.02Å; I104-T106 VanDerWaalsContact C-N 3.25Å; I104-T106 PolarHBondContact O-N 2.92Å; T106-N108 VanDerWaalsContact C-N 3.33Å; T106-N108 PolarHBondContact O-N 3.12Å; T106-T109 PolarHBondContact O-N 3.39Å; T106-Q110 WeakPolarHBondContact O-CG 3.49Å; T106-Q110 PolarHBondContact O-N 2.96Å
107	I	97.9	Very high	97.5	Very high	20 Å²	20	71.9 Å²	71.9	10%	0.103	36%	0.362	C	S	.	.	H	α-helix	trans	-61.6	-43	177.1	-68.6	168.9	0	0	0	110.5	M43 K46 A47 L50 V103 I104 T109 Q110 M111	M43-I107 HydrophobicContact CB-CG2 3.98Å; M43-I107 WeakPolarHBondContact O-CG2 3.47Å; K46-I107 HydrophobicContact CG-CD1 4.17Å; A47-I107 HydrophobicContact CB-CG2 4Å; L50-I107 HydrophobicContact CD1-CD1 3.79Å; V103-I107 HydrophobicContact CG1-CD1 3.92Å; V103-I107 HydrophobicContact CG1-CG1 4.41Å; V103-I107 WeakPolarHBondContact O-CG1 3.39Å; V103-I107 PolarHBondContact O-N 3.2Å; I104-I107 PolarHBondContact O-N 2.94Å; I107-T109 VanDerWaalsContact C-N 3.33Å; I107-T109 PolarHBondContact O-N 2.88Å; I107-Q110 PolarHBondContact O-N 2.99Å; I107-M111 VanDerWaalsContact O-CB 3.25Å; I107-M111 WeakPolarHBondContact O-CB 3.48Å; I107-M111 PolarHBondContact O-N 3.36Å
108	N	97.5	Very high	97.4	Very high	51 Å²	51	69.2 Å²	69.2	27%	0.273	35%	0.35	S	S	.	.	H	α-helix	trans	-61.6	-42.5	177.5	-79.3	-28.7	0	0	0	111.7	I104 E105 T106 M111 Q112	I104-N108 WeakPolarHBondContact O-CB 3.43Å; I104-N108 PolarHBondContact O-N 3.37Å; I104-N108 PolarHBondContact O-ND2 3.47Å; E105-N108 PolarHBondContact O-N 2.96Å; T106-N108 VanDerWaalsContact C-N 3.33Å; T106-N108 PolarHBondContact O-N 3.12Å; N108-M111 PolarHBondContact O-N 3.1Å; N108-Q112 WeakPolarHBondContact O-CG 3.49Å; N108-Q112 PolarHBondContact O-N 2.91Å
109	T	97.9	Very high	97.3	Very high	93 Å²	93	68.1 Å²	68.1	57%	0.571	35%	0.35	S	S	*	.	H	α-helix	trans	-62.8	-46	175.3	-57.3	0	0	0	0	111.4	E105 T106 I107 M111 Q112 A113	E105-T109 PolarHBondContact O-N 3.3Å; E105-T109 PolarHBondContact O-OG1 3.41Å; T106-T109 PolarHBondContact O-N 3.39Å; I107-T109 VanDerWaalsContact C-N 3.33Å; I107-T109 PolarHBondContact O-N 2.88Å; T109-M111 VanDerWaalsContact C-N 3.34Å; T109-M111 PolarHBondContact O-N 2.97Å; T109-Q112 PolarHBondContact O-N 3.25Å; T109-A113 PolarHBondContact O-N 3.5Å
110	Q	97.3	Very high	97.2	Very high	107 Å²	107	68.1 Å²	68.1	50%	0.5	35%	0.351	S	S	.	.	H	α-helix	trans	-63.1	-39.9	176.7	-71.5	177.7	-3.1	0	0	112	M43 T106 I107 A113 K114	M43-Q110 HydrophobicContact SD-CB 3.85Å; T106-Q110 WeakPolarHBondContact O-CG 3.49Å; T106-Q110 PolarHBondContact O-N 2.96Å; I107-Q110 PolarHBondContact O-N 2.99Å; Q110-A113 PolarHBondContact O-N 2.84Å; Q110-K114 WeakPolarHBondContact O-CB 3.45Å; Q110-K114 PolarHBondContact O-N 2.86Å
111	M	96.6	Very high	97.1	Very high	45 Å²	45	68.3 Å²	68.3	22%	0.222	35%	0.35	C	S	.	.	H	α-helix	trans	-65.3	-39.4	177.9	-175.5	173.5	61.4	0	0	112	Q40 M43 A44 I107 N108 T109 K114 G115	Q40-M111 HydrophobicContact CG-CG 3.91Å; M43-M111 HydrophobicContact CB-CB 4.46Å; M43-M111 HydrophobicContact CE-CB 4.43Å; A44-M111 HydrophobicContact CB-SD 3.78Å; I107-M111 VanDerWaalsContact O-CB 3.25Å; I107-M111 WeakPolarHBondContact O-CB 3.48Å; I107-M111 PolarHBondContact O-N 3.36Å; N108-M111 PolarHBondContact O-N 3.1Å; T109-M111 VanDerWaalsContact C-N 3.34Å; T109-M111 PolarHBondContact O-N 2.97Å; M111-K114 PolarHBondContact O-N 3.49Å; M111-G115 PolarHBondContact O-N 3.46Å
112	Q	96.4	Very high	96.8	Very high	117 Å²	117	71.3 Å²	71.3	55%	0.547	36%	0.355	S	S	.	.	H	α-helix	trans	-66.3	-45.7	173.5	-72.7	178.6	16.9	0	0	111.8	N108 T109 K114 G115 R116	N108-Q112 WeakPolarHBondContact O-CG 3.49Å; N108-Q112 PolarHBondContact O-N 2.91Å; T109-Q112 PolarHBondContact O-N 3.25Å; Q112-K114 VanDerWaalsContact C-N 3.3Å; Q112-K114 PolarHBondContact O-N 3.29Å; Q112-G115 PolarHBondContact O-N 3.47Å; Q112-R116 WeakPolarHBondContact O-CG 3.44Å; Q112-R116 PolarHBondContact O-N 3.08Å
113	A	97.4	Very high	96.6	Very high	44 Å²	44	72.7 Å²	72.7	36%	0.364	36%	0.363	S	S	.	.	H	α-helix	trans	-57.9	-45.6	175.2	0	0	0	0	0	110.9	T109 Q110 G115 R116 E117	T109-A113 PolarHBondContact O-N 3.5Å; Q110-A113 PolarHBondContact O-N 2.84Å; A113-G115 VanDerWaalsContact C-N 3.32Å; A113-G115 PolarHBondContact O-N 2.91Å; A113-R116 WeakPolarHBondContact O-CB 3.43Å; A113-R116 PolarHBondContact O-N 2.92Å; A113-R116 VanDerWaalsContact O-N 3.15Å; A113-E117 PolarHBondContact O-N 3.4Å
114	K	97.1	Very high	96.4	Very high	35 Å²	35	77.1 Å²	77.1	15%	0.152	37%	0.372	C	S	.	.	H	α-helix	trans	-63.7	-36	176.8	-159.4	67.9	172.3	-172.7	0	113.3	E39 Q40 M43 Q110 M111 Q112 R116 E117 L118	E39-K114 WeakPolarHBondContact OE2-CE 3.25Å; E39-K114 IonicContact OE2-NZ 2.73Å; E39-K114 PolarHBondContact OE2-NZ 3.04Å; Q40-K114 HydrophobicContact CB-CG 4.4Å; M43-K114 HydrophobicContact CE-CB 3.71Å; M43-K114 HydrophobicContact CE-CG 3.88Å; Q110-K114 WeakPolarHBondContact O-CB 3.45Å; Q110-K114 PolarHBondContact O-N 2.86Å; M111-K114 PolarHBondContact O-N 3.49Å; Q112-K114 VanDerWaalsContact C-N 3.3Å; Q112-K114 PolarHBondContact O-N 3.29Å; K114-R116 VanDerWaalsContact C-N 3.34Å; K114-E117 WeakPolarHBondContact CD-OE2 3.48Å; K114-E117 IonicContact NZ-OE2 3.47Å; K114-E117 PolarHBondContact NZ-OE2 2.94Å; K114-E117 PolarHBondContact O-N 3.31Å; K114-L118 WeakPolarHBondContact O-CB 3.4Å; K114-L118 WeakPolarHBondContact O-CG 3.33Å; K114-L118 PolarHBondContact O-N 2.73Å
115	G	95.3	Very high	96.1	Very high	17 Å²	17	79.3 Å²	79.3	18%	0.175	38%	0.38	C	S	.	.	H	α-helix	trans	-61.2	-42.3	173.2	0	0	0	0	0	112.2	M111 Q112 A113 L118 T119	M111-G115 PolarHBondContact O-N 3.46Å; Q112-G115 PolarHBondContact O-N 3.47Å; A113-G115 VanDerWaalsContact C-N 3.32Å; A113-G115 PolarHBondContact O-N 2.91Å; G115-L118 WeakPolarHBondContact O-CB 3.47Å; G115-L118 PolarHBondContact O-N 3.28Å; G115-T119 PolarHBondContact O-N 3.29Å; G115-T119 VanDerWaalsContact O-N 3.1Å; G115-T119 PolarHBondContact O-OG1 2.89Å
116	R	97.4	Very high	95.8	Very high	166 Å²	166	78.4 Å²	78.4	63%	0.626	38%	0.379	S	S	*	.	H	α-helix	trans	-65.2	-47.1	174.5	-63.2	175.9	-166.8	-179.5	4.8	111.4	Q112 A113 K114 L118 T119 E120	Q112-R116 WeakPolarHBondContact O-CG 3.44Å; Q112-R116 PolarHBondContact O-N 3.08Å; A113-R116 WeakPolarHBondContact O-CB 3.43Å; A113-R116 PolarHBondContact O-N 2.92Å; A113-R116 VanDerWaalsContact O-N 3.15Å; K114-R116 VanDerWaalsContact C-N 3.34Å; R116-L118 VanDerWaalsContact C-N 3.26Å; R116-L118 PolarHBondContact O-N 3Å; R116-T119 PolarHBondContact O-N 2.92Å; R116-T119 VanDerWaalsContact O-N 3.12Å; R116-E120 WeakPolarHBondContact O-CG 3.4Å; R116-E120 PolarHBondContact O-N 3.47Å
117	E	96.5	Very high	95.3	Very high	89 Å²	89	75.1 Å²	75.1	42%	0.416	36%	0.359	S	S	.	.	H	α-helix	trans	-56.8	-40.3	175.3	-70.3	177.6	-164.4	0	0	111.9	M36 A113 K114 Y121	M36-E117 HydrophobicContact CE-CB 3.57Å; A113-E117 PolarHBondContact O-N 3.4Å; K114-E117 WeakPolarHBondContact CD-OE2 3.48Å; K114-E117 IonicContact NZ-OE2 3.47Å; K114-E117 PolarHBondContact NZ-OE2 2.94Å; K114-E117 PolarHBondContact O-N 3.31Å; E117-Y121 WeakPolarHBondContact O-CB 2.91Å; E117-Y121 PolarHBondContact O-N 3.26Å
118	L	95.7	Very high	94.7	Very high	12 Å²	12	81.9 Å²	81.9	6%	0.063	38%	0.383	C	S	.	.	H	α-helix	trans	-62.7	-44.5	176.2	-87	166.7	0	0	0	112.1	F33 M36 R37 Q40 K114 G115 R116 Y121 R122	F33-L118 HydrophobicContact CD2-CD2 3.66Å; F33-L118 HydrophobicContact CE2-CD2 3.53Å; F33-L118 HydrophobicContact CZ-CD2 4.29Å; M36-L118 HydrophobicContact CB-CD2 3.53Å; M36-L118 HydrophobicContact CB-CG 4.05Å; M36-L118 HydrophobicContact CE-CD2 4.38Å; M36-L118 HydrophobicContact CE-CG 4.25Å; R37-L118 HydrophobicContact CG-CD1 4.23Å; R37-L118 HydrophobicContact CG-CD2 3.69Å; Q40-L118 HydrophobicContact CB-CD1 4.15Å; K114-L118 WeakPolarHBondContact O-CB 3.4Å; K114-L118 WeakPolarHBondContact O-CG 3.33Å; K114-L118 PolarHBondContact O-N 2.73Å; G115-L118 WeakPolarHBondContact O-CB 3.47Å; G115-L118 PolarHBondContact O-N 3.28Å; R116-L118 VanDerWaalsContact C-N 3.26Å; R116-L118 PolarHBondContact O-N 3Å; L118-Y121 PolarHBondContact O-N 3.01Å; L118-R122 VanDerWaalsContact O-CB 3.28Å; L118-R122 WeakPolarHBondContact O-CB 3.18Å; L118-R122 PolarHBondContact O-N 3.24Å
119	T	95.1	Very high	93.7	Very high	74 Å²	74	80.3 Å²	80.3	45%	0.454	37%	0.374	S	S	.	.	H	α-helix	trans	-63	-49.1	176.4	-59.5	0	0	0	0	111	G115 R116 Y121 R122 E123	G115-T119 PolarHBondContact O-N 3.29Å; G115-T119 VanDerWaalsContact O-N 3.1Å; G115-T119 PolarHBondContact O-OG1 2.89Å; R116-T119 PolarHBondContact O-N 2.92Å; R116-T119 VanDerWaalsContact O-N 3.12Å; T119-Y121 VanDerWaalsContact C-N 3.32Å; T119-Y121 PolarHBondContact O-N 3.46Å; T119-R122 WeakPolarHBondContact O-CB 3.4Å; T119-R122 PolarHBondContact O-N 2.87Å; T119-E123 WeakPolarHBondContact O-CG 3.3Å; T119-E123 PolarHBondContact O-N 3.47Å
120	E	96.6	Very high	92.1	Very high	108 Å²	108	79.4 Å²	79.4	51%	0.505	37%	0.369	S	S	.	.	H	α-helix	trans	-60.6	-40.9	177.8	-70.4	176	-161.7	0	0	112.1	R116 E123 R124	R116-E120 WeakPolarHBondContact O-CG 3.4Å; R116-E120 PolarHBondContact O-N 3.47Å; E120-E123 PolarHBondContact O-N 2.97Å; E120-R124 VanDerWaalsContact O-CB 3.23Å; E120-R124 WeakPolarHBondContact O-CB 3.49Å; E120-R124 PolarHBondContact O-N 3.34Å
121	Y	95.3	Very high	90.3	Very high	31 Å²	31	77.6 Å²	77.6	12%	0.122	38%	0.379	C	S	.	.	H	α-helix	trans	-68	-38.7	178.1	-162.8	-90.4	0	0	0	111.7	V29 T32 F33 M36 E117 L118 T119 Y125 I127	V29-Y121 WeakPolarHBondContact CA-OH 3.23Å; V29-Y121 HydrophobicContact CG1-CE1 3.85Å; V29-Y121 WeakPolarHBondContact O-CE1 3.39Å; T32-Y121 WeakPolarHBondContact CB-OH 3.47Å; T32-Y121 HydrophobicContact CG2-CE1 4.44Å; T32-Y121 HydrophobicContact CG2-CE2 4.15Å; F33-Y121 HydrophobicContact CB-CD1 4.01Å; F33-Y121 HydrophobicContact CB-CE1 3.99Å; F33-Y121 AromaticContact CD2-CD1 3.96Å; F33-Y121 HydrophobicContact CD2-CD1 3.96Å; F33-Y121 HydrophobicContact CG-CD1 4.45Å; M36-Y121 HydrophobicContact SD-CD2 4.39Å; M36-Y121 HydrophobicContact SD-CG 4.3Å; E117-Y121 WeakPolarHBondContact O-CB 2.91Å; E117-Y121 PolarHBondContact O-N 3.26Å; L118-Y121 PolarHBondContact O-N 3.01Å; T119-Y121 VanDerWaalsContact C-N 3.32Å; T119-Y121 PolarHBondContact O-N 3.46Å; Y121-Y125 HydrophobicContact CD1-CD2 4.04Å; Y121-Y125 HydrophobicContact CD2-CD2 4.13Å; Y121-Y125 AromaticContact CD2-CE2 3.9Å; Y121-Y125 HydrophobicContact CD2-CE2 3.9Å; Y121-Y125 AromaticContact CE1-CD2 3.81Å; Y121-Y125 HydrophobicContact CE1-CD2 3.81Å; Y121-Y125 HydrophobicContact CE1-CE2 4.16Å; Y121-Y125 AromaticContact CE2-CD2 3.91Å; Y121-Y125 HydrophobicContact CE2-CD2 3.91Å; Y121-Y125 AromaticContact CE2-CE2 3.44Å; Y121-Y125 HydrophobicContact CE2-CE2 3.44Å; Y121-Y125 VanDerWaalsContact CE2-CE2 3.44Å; Y121-Y125 HydrophobicContact CG-CD2 4.2Å; Y121-Y125 HydrophobicContact CG-CE2 4.43Å; Y121-Y125 AromaticContact CZ-CD2 3.73Å; Y121-Y125 AromaticContact CZ-CE2 3.58Å; Y121-Y125 WeakPolarHBondContact O-CD2 3.44Å; Y121-Y125 PolarHBondContact O-N 2.77Å; Y121-I127 HydrophobicContact CD1-CD1 3.66Å; Y121-I127 HydrophobicContact CE1-CD1 3.83Å
122	R	92.1	Very high	88.1	Confident	102 Å²	102	81.7 Å²	81.7	39%	0.385	40%	0.398	S	S	.	.	H	α-helix	trans	-61	-47.3	174.6	-178.4	-174.4	-177.5	165.8	-0.9	111.1	F33 L118 T119 N126 I127	F33-R122 HydrophobicContact CE2-CB 4.01Å; F33-R122 HydrophobicContact CZ-CB 4.46Å; L118-R122 VanDerWaalsContact O-CB 3.28Å; L118-R122 WeakPolarHBondContact O-CB 3.18Å; L118-R122 PolarHBondContact O-N 3.24Å; T119-R122 WeakPolarHBondContact O-CB 3.4Å; T119-R122 PolarHBondContact O-N 2.87Å; R122-N126 WeakPolarHBondContact O-CA 3.45Å; R122-N126 PolarHBondContact O-N 3.23Å; R122-I127 HydrophobicContact CG-CB 4.08Å; R122-I127 WeakPolarHBondContact CG-O 3.45Å; R122-I127 PolarHBondContact NE-O 3.4Å; R122-I127 PolarHBondContact O-N 3.49Å
123	E	93.6	Very high	85.3	Confident	134 Å²	134	79 Å²	79	63%	0.626	40%	0.401	S	S	*	.	H	α-helix	trans	-66.6	-45.9	179.8	-71.5	175.7	-174	0	0	111.7	T119 E120 Y125 N126	T119-E123 WeakPolarHBondContact O-CG 3.3Å; T119-E123 PolarHBondContact O-N 3.47Å; E120-E123 PolarHBondContact O-N 2.97Å; E123-Y125 VanDerWaalsContact C-N 3.26Å; E123-Y125 PolarHBondContact O-N 2.95Å; E123-N126 PolarHBondContact O-N 3Å
124	R	94.2	Very high	82.7	Confident	164 Å²	164	87 Å²	87	62%	0.619	43%	0.431	S	S	*	.	H	α-helix	trans	-58.5	-35.2	-178.4	-176.2	-178.5	-60.5	177.7	4.7	113.7	E120	E120-R124 VanDerWaalsContact O-CB 3.23Å; E120-R124 WeakPolarHBondContact O-CB 3.49Å; E120-R124 PolarHBondContact O-N 3.34Å
125	Y	92.3	Very high	80.1	Confident	59 Å²	59	88.6 Å²	88.6	23%	0.231	46%	0.457	C	S	.	.	T	Hydrogen-bonded Turn	trans	-114.5	16.3	-177.4	-63.3	-77.3	0	0	0	113.3	P24 V29 Y121 E123 I127	P24-Y125 HydrophobicContact CG-CE1 3.96Å; P24-Y125 WeakPolarHBondContact CG-OH 3.41Å; V29-Y125 HydrophobicContact CB-CG 4.48Å; V29-Y125 VanDerWaalsContact CG1-CB 3.49Å; V29-Y125 HydrophobicContact CG1-CD1 4.05Å; V29-Y125 HydrophobicContact CG1-CD2 3.98Å; V29-Y125 HydrophobicContact CG1-CG 3.58Å; V29-Y125 HydrophobicContact CG2-CD1 3.64Å; V29-Y125 HydrophobicContact CG2-CD2 4.43Å; V29-Y125 HydrophobicContact CG2-CE1 3.76Å; V29-Y125 HydrophobicContact CG2-CG 4Å; Y121-Y125 HydrophobicContact CD1-CD2 4.04Å; Y121-Y125 HydrophobicContact CD2-CD2 4.13Å; Y121-Y125 AromaticContact CD2-CE2 3.9Å; Y121-Y125 HydrophobicContact CD2-CE2 3.9Å; Y121-Y125 AromaticContact CE1-CD2 3.81Å; Y121-Y125 HydrophobicContact CE1-CD2 3.81Å; Y121-Y125 HydrophobicContact CE1-CE2 4.16Å; Y121-Y125 AromaticContact CE2-CD2 3.91Å; Y121-Y125 HydrophobicContact CE2-CD2 3.91Å; Y121-Y125 AromaticContact CE2-CE2 3.44Å; Y121-Y125 HydrophobicContact CE2-CE2 3.44Å; Y121-Y125 VanDerWaalsContact CE2-CE2 3.44Å; Y121-Y125 HydrophobicContact CG-CD2 4.2Å; Y121-Y125 HydrophobicContact CG-CE2 4.43Å; Y121-Y125 AromaticContact CZ-CD2 3.73Å; Y121-Y125 AromaticContact CZ-CE2 3.58Å; Y121-Y125 WeakPolarHBondContact O-CD2 3.44Å; Y121-Y125 PolarHBondContact O-N 2.77Å; E123-Y125 VanDerWaalsContact C-N 3.26Å; E123-Y125 PolarHBondContact O-N 2.95Å; Y125-I127 PolarHBondContact O-N 3.4Å; Y125-I127 VanDerWaalsContact O-N 3.08Å
126	N	90.8	Very high	77.5	Confident	105 Å²	105	95.4 Å²	95.4	56%	0.561	49%	0.49	S	S	*	.	T	Hydrogen-bonded Turn	trans	48	40.8	178	-66.7	90.9	0	0	0	113.8	R122 E123 R128	R122-N126 WeakPolarHBondContact O-CA 3.45Å; R122-N126 PolarHBondContact O-N 3.23Å; E123-N126 PolarHBondContact O-N 3Å; N126-R128 PolarHBondContact O-N 3.23Å
127	I	89.1	Confident	74.7	Confident	4 Å²	4	93.6 Å²	93.6	2%	0.021	50%	0.497	C	S	.	.			trans	-70.3	124.6	-174.5	-56.8	-177.8	0	0	0	110	V29 F33 Y121 R122 Y125 V159 L160 V161	V29-I127 HydrophobicContact CG1-CD1 3.76Å; V29-I127 HydrophobicContact CG1-CG1 4.15Å; F33-I127 HydrophobicContact CB-CD1 3.68Å; F33-I127 HydrophobicContact CD1-CD1 4.26Å; F33-I127 HydrophobicContact CD1-CG2 3.98Å; F33-I127 HydrophobicContact CD2-CD1 3.81Å; F33-I127 HydrophobicContact CE1-CG2 4.01Å; F33-I127 HydrophobicContact CG-CD1 3.66Å; F33-I127 HydrophobicContact CG-CG2 4.41Å; F33-I127 HydrophobicContact CZ-CG2 4.48Å; Y121-I127 HydrophobicContact CD1-CD1 3.66Å; Y121-I127 HydrophobicContact CE1-CD1 3.83Å; R122-I127 HydrophobicContact CG-CB 4.08Å; R122-I127 WeakPolarHBondContact CG-O 3.45Å; R122-I127 PolarHBondContact NE-O 3.4Å; R122-I127 PolarHBondContact O-N 3.49Å; Y125-I127 PolarHBondContact O-N 3.4Å; Y125-I127 VanDerWaalsContact O-N 3.08Å; I127-V159 HydrophobicContact CG2-CG1 3.19Å; I127-L160 WeakPolarHBondContact CA-O 3.28Å; I127-V161 HydrophobicContact CG1-CG2 4.28Å
128	R	84.8	Confident	71.9	Confident	163 Å²	163	98.4 Å²	98.4	62%	0.615	52%	0.52	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-107.4	125.7	174.7	-60.8	-174.8	-174.7	-164.2	0.9	110.3	N126 V130 V159 L160	N126-R128 PolarHBondContact O-N 3.23Å; R128-V130 PolarHBondContact O-N 3.33Å; R128-V159 WeakPolarHBondContact O-CA 3.42Å; R128-L160 HydrophobicContact CB-CB 4.41Å; R128-L160 PolarHBondContact N-O 3.3Å; R128-L160 PolarHBondContact O-N 3.19Å
129	L	75.5	Confident	69	Low	17 Å²	17	101.5 Å²	101.5	9%	0.089	55%	0.554	C	S	.	*	E	Extended strand (participates in β ladder)	trans	-84.1	105.7	173.4	-78.4	158.4	0	0	0	108.9	F33 G131 E132 G158 V159	F33-L129 HydrophobicContact CE1-CD1 4.36Å; F33-L129 HydrophobicContact CE1-CD2 4.13Å; F33-L129 HydrophobicContact CE1-CG 4.3Å; F33-L129 HydrophobicContact CZ-CD1 4.39Å; L129-G131 PolarHBondContact O-N 3.23Å; L129-E132 WeakPolarHBondContact CD1-OE2 3.45Å; L129-E132 PolarHBondContact O-N 2.74Å; L129-G158 CarbonylContact C-O 3.55Å; L129-V159 HydrophobicContact CD2-CG2 4.01Å
130	V	64.5	Low	66.4	Low	75 Å²	75	107 Å²	107	46%	0.455	58%	0.575	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-74.1	107.7	172.1	-171.6	0	0	0	0	108	R128 A157 G158 L160	R128-V130 PolarHBondContact O-N 3.33Å; V130-A157 CarbonylContact O-C 3.51Å; V130-A157 WeakPolarHBondContact O-CA 3.32Å; V130-G158 WeakPolarHBondContact CA-O 3.44Å; V130-G158 WeakPolarHBondContact CB-O 3.42Å; V130-G158 PolarHBondContact N-O 3.01Å; V130-G158 PolarHBondContact O-N 2.91Å; V130-L160 HydrophobicContact CG2-CB 4.32Å; V130-L160 HydrophobicContact CG2-CD1 3.24Å; V130-L160 HydrophobicContact CG2-CG 3.43Å; V130-L160 VanDerWaalsContact CG2-CG 3.43Å
131	G	60.1	Low	63.6	Low	69 Å²	69	107.1 Å²	107.1	71%	0.711	59%	0.588	S	S	*	*	T	Hydrogen-bonded Turn	trans	135.6	-17.1	-173.8	0	0	0	0	0	113.2	L129	L129-G131 PolarHBondContact O-N 3.23Å
132	E	50.2	Low	60.9	Low	131 Å²	131	110.6 Å²	110.6	61%	0.612	62%	0.622	S	S	*	*	S	Bend	trans	-99.5	76.7	158	-72.5	173.1	122.3	0	0	106.7	L129	L129-E132 WeakPolarHBondContact CD1-OE2 3.45Å; L129-E132 PolarHBondContact O-N 2.74Å
133	G	38.3	Very low	58.5	Low	60 Å²	60	110.1 Å²	110.1	62%	0.619	64%	0.641	S	S	*	*			trans	-57.9	140	169.8	0	0	0	0	0	109.8	G135	G133-G135 PolarHBondContact O-N 3.07Å
134	E	43.3	Very low	56.3	Low	212 Å²	212	109.2 Å²	109.2	99%	0.991	65%	0.646	S	S	*	*	S	Bend	trans	-0.1	93.6	152.8	-70.9	154.5	96.5	0	0	114.4
135	G	41.7	Very low	53.8	Low	69 Å²	69	107.4 Å²	107.4	71%	0.711	66%	0.659	S	S	*	*			trans	-142	9.6	-178.3	0	0	0	0	0	114.9	G133	G133-G135 PolarHBondContact O-N 3.07Å
136	D	40.9	Very low	50.8	Low	160 Å²	160	108.5 Å²	108.5	86%	0.856	69%	0.688	S	S	*	*	S	Bend	trans	-139.1	41.7	-177.7	-112.5	-44.3	0	0	0	113.5
137	T	39.2	Very low	48.5	Very low	127 Å²	127	110.6 Å²	110.6	78%	0.779	70%	0.699	S	S	*	*	S	Bend	trans	-146	112.4	161.7	-30.2	0	0	0	0	111.5
138	Q	37.7	Very low	45.9	Very low	191 Å²	191	116 Å²	116	89%	0.893	74%	0.738	S	S	*	*			trans	86.1	120.9	164.9	-70.9	166.5	19.7	0	0	118.8
139	G	33.7	Very low	43.6	Very low	76 Å²	76	117 Å²	117	78%	0.784	75%	0.749	S	S	*	*			trans	-86.5	-178.5	-179.2	0	0	0	0	0	115.6
140	Q	40.1	Very low	41.5	Very low	191 Å²	191	120.1 Å²	120.1	89%	0.893	79%	0.785	S	S	*	*			trans	84	93.1	160	-132.8	166.3	83.4	0	0	116.9
141	S	37.8	Very low	39.9	Very low	110 Å²	110	120 Å²	120	77%	0.769	80%	0.8	S	S	*	*				161.3	132.9	107.2	-70.1	0	0	0	0	113.6
142	A	39.6	Very low	39.1	Very low	103 Å²	103	120.7 Å²	120.7	85%	0.851	81%	0.807	S	S	*	*			trans	44.6	125	149.2	0	0	0	0	0	122.3
143	A	40.4	Very low	38.5	Very low	93 Å²	93	120 Å²	120	77%	0.769	82%	0.817	S	S	*	*			trans	-58.8	171.7	162.9	0	0	0	0	0	112.9
144	P	48.7	Very low	38.7	Very low	115 Å²	115	127.4 Å²	127.4	75%	0.747	83%	0.832	S	S	*	*			cis	-149.6	169.4	31.1	40.9	-17.9	0	0	0	120.1
145	S	40.4	Very low	38.5	Very low	125 Å²	125	123.5 Å²	123.5	87%	0.874	83%	0.828	S	S	*	*			trans	49.7	124.1	148.2	-47.5	0	0	0	0	123
146	G	31.1	Very low	38.7	Very low	83 Å²	83	123.2 Å²	123.2	86%	0.856	83%	0.825	S	S	*	*			trans	-175.9	110.4	158.7	0	0	0	0	0	113.7
147	N	40.8	Very low	39.3	Very low	148 Å²	148	117.8 Å²	117.8	79%	0.791	80%	0.802	S	S	*	*			trans	-68.7	132	177.4	177.1	86.3	0	0	0	112.6
148	S	34.9	Very low	40.2	Very low	118 Å²	118	113.2 Å²	113.2	83%	0.825	78%	0.781	S	S	*	*			trans	-163.1	126.2	153.5	-111.6	0	0	0	0	113.2
149	E	35.9	Very low	41.8	Very low	183 Å²	183	105.1 Å²	105.1	86%	0.855	74%	0.744	S	S	*	*			trans	-56.2	154.2	166.8	-79.8	161.1	75.5	0	0	113.8
150	G	32	Very low	43.7	Very low	83 Å²	83	106.4 Å²	106.4	86%	0.856	73%	0.733	S	S	*	*			trans	121.9	121.9	144.7	0	0	0	0	0	115.4
151	G	31.3	Very low	45.1	Very low	73 Å²	73	99.4 Å²	99.4	75%	0.753	70%	0.703	S	S	*	*			trans	128.9	84.8	152	0	0	0	0	0	114.7	S153	G151-S153 PolarHBondContact O-N 2.92Å
152	G	43.9	Very low	46.2	Very low	84 Å²	84	100.3 Å²	100.3	87%	0.866	71%	0.709	S	S	*	*			trans	-56.6	123.9	158.7	0	0	0	0	0	109.8
153	S	36.3	Very low	46.5	Very low	117 Å²	117	100.2 Å²	100.2	82%	0.818	70%	0.702	S	S	*	*			trans	-141	125.6	165	-82.4	0	0	0	0	108.7	G151 S155	G151-S153 PolarHBondContact O-N 2.92Å; S153-S155 PolarHBondContact O-N 3.17Å; S153-S155 VanDerWaalsContact O-N 3.11Å
154	K	44.1	Very low	46.9	Very low	214 Å²	214	100.5 Å²	100.5	93%	0.93	70%	0.698	S	S	*	*			trans	-45.4	114.1	-177.7	-68.4	170.6	174.8	175	0	110.3	G156	K154-G156 PolarHBondContact O-N 3.22Å
155	S	38.7	Very low	46.8	Very low	130 Å²	130	99.7 Å²	99.7	91%	0.909	70%	0.696	S	S	*	*			trans	-71.2	70.1	170.9	174.1	0	0	0	0	110.1	S153	S153-S155 PolarHBondContact O-N 3.17Å; S153-S155 VanDerWaalsContact O-N 3.11Å
156	G	44.6	Very low	47.1	Very low	64 Å²	64	98.2 Å²	98.2	66%	0.66	69%	0.685	S	S	*	*			trans	-99.1	93.4	161.8	0	0	0	0	0	107.5	K154 G158	K154-G156 PolarHBondContact O-N 3.22Å; G156-G158 PolarHBondContact O-N 3.07Å
157	A	53.3	Low	48.1	Very low	45 Å²	45	99.2 Å²	99.2	37%	0.372	68%	0.675	S	S	.	*			trans	-55.2	111.8	173.4	0	0	0	0	0	108.8	V130	V130-A157 CarbonylContact O-C 3.51Å; V130-A157 WeakPolarHBondContact O-CA 3.32Å
158	G	59.9	Low	48.6	Very low	32 Å²	32	95.9 Å²	95.9	33%	0.33	67%	0.667	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-69.2	149.3	177.3	0	0	0	0	0	109.5	L129 V130 G156	L129-G158 CarbonylContact C-O 3.55Å; V130-G158 WeakPolarHBondContact CA-O 3.44Å; V130-G158 WeakPolarHBondContact CB-O 3.42Å; V130-G158 PolarHBondContact N-O 3.01Å; V130-G158 PolarHBondContact O-N 2.91Å; G156-G158 PolarHBondContact O-N 3.07Å
159	V	70.4	Confident	49.6	Very low	21 Å²	21	94.4 Å²	94.4	13%	0.127	66%	0.656	C	S	.	*	E	Extended strand (participates in β ladder)	trans	-122.6	120	179.3	-177.8	0	0	0	0	107.3	V30 F33 Q34 I127 R128 L129	V30-V159 HydrophobicContact CB-CG1 4.35Å; V30-V159 HydrophobicContact CG1-CB 3.71Å; V30-V159 HydrophobicContact CG1-CG1 3.93Å; V30-V159 HydrophobicContact CG1-CG2 4.43Å; V30-V159 HydrophobicContact CG2-CB 4.3Å; V30-V159 HydrophobicContact CG2-CG1 3.89Å; F33-V159 HydrophobicContact CD1-CG1 4.1Å; F33-V159 HydrophobicContact CD1-CG2 4.45Å; Q34-V159 HydrophobicContact CG-CG2 4.15Å; I127-V159 HydrophobicContact CG2-CG1 3.19Å; R128-V159 WeakPolarHBondContact O-CA 3.42Å; L129-V159 HydrophobicContact CD2-CG2 4.01Å
160	L	73.3	Confident	50.7	Low	102 Å²	102	87.5 Å²	87.5	53%	0.534	64%	0.64	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-107.2	141.8	176.3	-66.1	169.3	0	0	0	109.9	I127 R128 V130	I127-L160 WeakPolarHBondContact CA-O 3.28Å; R128-L160 HydrophobicContact CB-CB 4.41Å; R128-L160 PolarHBondContact N-O 3.3Å; R128-L160 PolarHBondContact O-N 3.19Å; V130-L160 HydrophobicContact CG2-CB 4.32Å; V130-L160 HydrophobicContact CG2-CD1 3.24Å; V130-L160 HydrophobicContact CG2-CG 3.43Å; V130-L160 VanDerWaalsContact CG2-CG 3.43Å
161	V	70	Confident	52.2	Low	45 Å²	45	87.9 Å²	87.9	27%	0.273	62%	0.622	S	S	.	*			trans	-114	134.5	172.2	174.4	0	0	0	0	106.9	A26 V29 V30 I127	A26-V161 HydrophobicContact CB-CB 4.29Å; A26-V161 HydrophobicContact CB-CG1 4.27Å; V29-V161 HydrophobicContact CB-CG2 4.32Å; V29-V161 HydrophobicContact CG1-CG2 3.82Å; V30-V161 HydrophobicContact CG2-CG2 3.45Å; V30-V161 VanDerWaalsContact CG2-CG2 3.45Å; I127-V161 HydrophobicContact CG1-CG2 4.28Å
162	S	60.9	Low	54.1	Low	128 Å²	128	89.3 Å²	89.3	90%	0.895	61%	0.61	S	S	*	*			trans	-112.7	0	179.9	-61.5	0	0	0	0	111.7

Retrieved 162 of 162 residues in 81.3 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).