A0A087XEE9_POEFO Loading...

Sialin

Receptor for CM101, a polysaccharide produced by group B Streptococcus with antipathoangiogenic properties.

AlphaFold DB (A0A3B3TRJ5), UniProt , Accession A0A087XEE9, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 506 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	24.3	Very low	29.9	Very low	239 Å²	239	144.1 Å²	144.1	100%	1.177	80%	0.797	S	S	*	*				0	137.5	0	-109.5	177.9	-178.7	0	0	108
2	P	43	Very low	29.7	Very low	103 Å²	103	145.3 Å²	145.3	67%	0.669	80%	0.801	S	S	*	*			cis	-144.1	178.8	-44.6	39.2	-21	0	0	0	114.4
3	L	29.3	Very low	29.7	Very low	157 Å²	157	146.5 Å²	146.5	82%	0.822	81%	0.806	S	S	*	*			trans	89.8	155.8	150.9	-65.5	169	0	0	0	120.6
4	P	42.4	Very low	29.7	Very low	93 Å²	93	142.8 Å²	142.8	60%	0.604	80%	0.796	S	S	*	*			cis	-142.9	173.2	-18.1	31	-8.5	0	0	0	117.7
5	N	29	Very low	29.6	Very low	162 Å²	162	138.5 Å²	138.5	87%	0.866	80%	0.796	S	S	*	*			trans	72.7	132.2	155.6	-59.2	-19.3	0	0	0	119
6	G	26.9	Very low	29.6	Very low	71 Å²	71	138.4 Å²	138.4	73%	0.732	79%	0.792	S	S	*	*			cis	143.4	129.3	4.8	0	0	0	0	0	111.2
7	R	26.6	Very low	29.7	Very low	255 Å²	255	137.9 Å²	137.9	96%	0.962	79%	0.793	S	S	*	*			trans	81.5	141.8	173.2	-66.4	180	175.5	174.6	-1.3	116.8
8	S	26.4	Very low	29.8	Very low	112 Å²	112	139.2 Å²	139.2	78%	0.783	79%	0.791	S	S	*	*			cis	-160.1	152	15.4	51	0	0	0	0	113.5
9	I	29.1	Very low	29.9	Very low	149 Å²	149	137.7 Å²	137.7	76%	0.764	79%	0.785	S	S	*	*			trans	-22.8	134.3	157	-62.9	157	0	0	0	118.5
10	N	25.5	Very low	30.1	Very low	134 Å²	134	138.7 Å²	138.7	72%	0.717	79%	0.787	S	S	*	*			trans	149.7	103.7	134.7	-91.8	-16.5	0	0	0	110.9
11	T	26.5	Very low	30.5	Very low	110 Å²	110	139.6 Å²	139.6	68%	0.675	79%	0.788	S	S	*	*				93.7	123.1	86.1	46.8	0	0	0	0	113.3
12	D	27.7	Very low	30.9	Very low	158 Å²	158	130.9 Å²	130.9	85%	0.845	76%	0.76	S	S	*	*			trans	77.9	85.1	148.7	-53.3	-15.1	0	0	0	118.9
13	D	29.9	Very low	30.6	Very low	161 Å²	161	135.9 Å²	135.9	86%	0.861	77%	0.771	S	S	*	*			trans	-108.7	151.9	150.1	-161.8	5.9	0	0	0	108.1
14	S	29.3	Very low	31.1	Very low	95 Å²	95	136.1 Å²	136.1	66%	0.664	77%	0.773	S	S	*	*			trans	81.8	78.9	-172.2	72.1	0	0	0	0	117.5	D16	S14-D16 PolarHBondContact O-N 3.33Å; S14-D16 VanDerWaalsContact O-N 3.08Å
15	G	28	Very low	31.4	Very low	78 Å²	78	134.8 Å²	134.8	80%	0.804	77%	0.77	S	S	*	*			trans	-76.9	59.2	155.6	0	0	0	0	0	111.7	T17	G15-T17 PolarHBondContact O-N 2.96Å
16	D	29.6	Very low	32.5	Very low	137 Å²	137	131.8 Å²	131.8	73%	0.733	76%	0.757	S	S	*	*			trans	-73.2	102.2	160.5	-80.3	-32.1	0	0	0	106.8	S14 E18	S14-D16 PolarHBondContact O-N 3.33Å; S14-D16 VanDerWaalsContact O-N 3.08Å; D16-E18 PolarHBondContact O-N 3.49Å
17	T	31.5	Very low	33.9	Very low	131 Å²	131	128.9 Å²	128.9	80%	0.804	73%	0.726	S	S	*	*			trans	-75.5	67.2	164.5	-44.6	0	0	0	0	107.4	G15 V19	G15-T17 PolarHBondContact O-N 2.96Å; T17-V19 VanDerWaalsContact C-N 3.28Å; T17-V19 PolarHBondContact O-N 3.13Å
18	E	31.3	Very low	35.4	Very low	160 Å²	160	121.3 Å²	121.3	75%	0.748	71%	0.71	S	S	*	*			trans	-65.1	96.7	165.1	-153.8	-178.7	-167	0	0	105.4	D16 L20	D16-E18 PolarHBondContact O-N 3.49Å; E18-L20 PolarHBondContact O-N 3.46Å
19	V	32.4	Very low	36.9	Very low	112 Å²	112	124 Å²	124	68%	0.679	70%	0.702	S	S	*	*			trans	-58.9	100.7	166.6	176.2	0	0	0	0	105.1	T17 L21	T17-V19 VanDerWaalsContact C-N 3.28Å; T17-V19 PolarHBondContact O-N 3.13Å; V19-L21 PolarHBondContact O-N 3.39Å
20	L	33.2	Very low	38.2	Very low	157 Å²	157	121.8 Å²	121.8	82%	0.822	70%	0.699	S	S	*	*			trans	-57.7	80.7	167.1	-77.4	164	0	0	0	107.8	E18 G22	E18-L20 PolarHBondContact O-N 3.46Å; L20-G22 PolarHBondContact O-N 2.83Å
21	L	38.5	Very low	40.1	Very low	157 Å²	157	121.4 Å²	121.4	82%	0.822	71%	0.706	S	S	*	*			trans	-61.9	89.9	156.4	-93.8	159.7	0	0	0	105	V19 K23	V19-L21 PolarHBondContact O-N 3.39Å; L21-K23 PolarHBondContact O-N 3.08Å; L21-K23 VanDerWaalsContact O-N 3.09Å
22	G	33.4	Very low	42.7	Very low	56 Å²	56	116.6 Å²	116.6	58%	0.577	68%	0.677	S	S	*	*			trans	-45.6	120.5	173.1	0	0	0	0	0	108.8	L20 D24	L20-G22 PolarHBondContact O-N 2.83Å; G22-D24 PolarHBondContact O-N 2.89Å
23	K	35.3	Very low	45.4	Very low	208 Å²	208	109.7 Å²	109.7	90%	0.904	64%	0.641	S	S	*	*	T	Hydrogen-bonded Turn	trans	-67.4	9.9	-174.6	-129.3	169.2	-179	168.3	0	113.8	L21	L21-K23 PolarHBondContact O-N 3.08Å; L21-K23 VanDerWaalsContact O-N 3.09Å
24	D	41.5	Very low	48.2	Very low	162 Å²	162	102.1 Å²	102.1	87%	0.866	60%	0.601	S	S	*	*	T	Hydrogen-bonded Turn	trans	-125.3	19.4	-168.7	-67.2	-32.7	0	0	0	115.2	G22	G22-D24 PolarHBondContact O-N 2.89Å
25	A	47.2	Very low	50.9	Low	66 Å²	66	100 Å²	100	55%	0.545	58%	0.581	S	S	.	*			trans	-114.9	23.4	-177.3	0	0	0	0	0	115.6	S27 Y266	A25-S27 PolarHBondContact O-N 2.99Å; A25-S27 VanDerWaalsContact O-N 3.16Å; A25-Y266 WeakPolarHBondContact O-CD2 3.4Å
26	V	53.4	Low	53.9	Low	98 Å²	98	99.1 Å²	99.1	59%	0.594	56%	0.563	S	S	*	*			trans	-79.6	97.7	167.7	-175.5	0	0	0	0	107.7
27	S	55.6	Low	56.8	Low	10 Å²	10	92.9 Å²	92.9	7%	0.07	53%	0.53	C	S	.	.			trans	-52.6	135.8	174.4	65.5	0	0	0	0	109.7	A25 R29 R34	A25-S27 PolarHBondContact O-N 2.99Å; A25-S27 VanDerWaalsContact O-N 3.16Å; S27-R29 PolarHBondContact O-N 3.34Å; S27-R34 PolarHBondContact OG-NH2 3.38Å
28	P	57.1	Low	59.6	Low	96 Å²	96	86.7 Å²	86.7	62%	0.623	49%	0.492	S	S	*	.			trans	-54.4	131.5	-174.9	19.4	-30.5	0	0	0	111.2	C30	P28-C30 PolarHBondContact O-N 3.05Å
29	R	59.4	Low	62.5	Low	168 Å²	168	82.2 Å²	82.2	63%	0.634	48%	0.476	S	S	*	.	S	Bend	trans	-64	-29.5	-178.4	-71.7	-177.2	169.9	175.4	-0.6	112.8	S27 L35 E195	S27-R29 PolarHBondContact O-N 3.34Å; R29-L35 WeakPolarHBondContact O-CD2 3.3Å; R29-E195 IonicContact CZ-OE1 2.72Å; R29-E195 IonicContact NE-OE1 3.69Å; R29-E195 PolarHBondContact NE-OE1 2.83Å; R29-E195 IonicContact NH2-OE1 3.61Å; R29-E195 PolarHBondContact NH2-OE1 3.34Å
30	C	55.3	Low	65.4	Low	103 Å²	103	77.7 Å²	77.7	70%	0.696	45%	0.447	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.2	127.6	178.8	-150.3	0	0	0	0	109.7	P28	P28-C30 PolarHBondContact O-N 3.05Å
31	C	65.6	Low	68.3	Low	127 Å²	127	70.2 Å²	70.2	86%	0.858	41%	0.408	S	S	*	.	T	Hydrogen-bonded Turn	trans	68.6	20.6	-177.9	-55.4	0	0	0	0	116.6
32	S	81.8	Confident	70.9	Confident	9 Å²	9	64.6 Å²	64.6	6%	0.063	38%	0.377	C	S	.	.			trans	-72.7	150.3	173.7	73.9	0	0	0	0	112.1	R34 L35 S36 E263	S32-R34 PolarHBondContact O-N 3.33Å; S32-L35 PolarHBondContact O-N 3.43Å; S32-L35 VanDerWaalsContact OG-CB 3.29Å; S32-L35 WeakPolarHBondContact OG-CB 3.41Å; S32-L35 PolarHBondContact OG-N 3.41Å; S32-S36 PolarHBondContact O-N 2.97Å; S32-E263 WeakPolarHBondContact CB-OE1 3.47Å
33	A	84.6	Confident	73.8	Confident	12 Å²	12	65.6 Å²	65.6	10%	0.099	37%	0.369	C	S	.	.	H	α-helix	trans	-61.2	-34.2	176.5	0	0	0	0	0	111.2	S36 L37 W190 I259 E263	A33-S36 PolarHBondContact O-N 2.97Å; A33-L37 PolarHBondContact O-N 2.77Å; A33-W190 HydrophobicContact CB-CZ3 4.21Å; A33-I259 HydrophobicContact CB-CB 4.31Å; A33-I259 HydrophobicContact CB-CD1 4.35Å; A33-I259 HydrophobicContact CB-CG1 3.99Å; A33-E263 PolarHBondContact N-OE1 3.4Å; A33-E263 PolarHBondContact N-OE2 2.99Å
34	R	87.8	Confident	76.6	Confident	2 Å²	2	55.8 Å²	55.8	1%	0.008	33%	0.327	C	S	.	.	H	α-helix	trans	-64.5	-42.8	175	-69.1	173.5	-71.7	141.5	-2.3	113.4	S27 S32 L37 A38 W190 E195 E263 I267	S27-R34 PolarHBondContact OG-NH2 3.38Å; S32-R34 PolarHBondContact O-N 3.33Å; R34-L37 WeakPolarHBondContact O-CB 3.31Å; R34-L37 PolarHBondContact O-N 3.29Å; R34-A38 PolarHBondContact O-N 3.28Å; R34-W190 WeakPolarHBondContact CD-O 3.44Å; R34-W190 HydrophobicContact CG-CE3 4.08Å; R34-E195 IonicContact CZ-OE2 3.79Å; R34-E195 IonicContact NH1-OE2 2.88Å; R34-E195 PolarHBondContact NH1-OE2 3.48Å; R34-E195 IonicContact NH2-OE2 3.94Å; R34-E263 VanDerWaalsContact CG-OE1 3.28Å; R34-E263 WeakPolarHBondContact CG-OE1 3.47Å; R34-E263 IonicContact CZ-OE1 3.25Å; R34-E263 PolarHBondContact N-OE1 3.33Å; R34-E263 VanDerWaalsContact N-OE1 3.15Å; R34-E263 IonicContact NE-OE1 3.09Å; R34-E263 PolarHBondContact NE-OE1 3.3Å; R34-E263 IonicContact NH2-OE1 3.5Å; R34-I267 VanDerWaalsContact CD-CD1 3.5Å; R34-I267 HydrophobicContact CG-CD1 3.72Å; R34-I267 HydrophobicContact CG-CG1 4.47Å
35	L	87.3	Confident	79	Confident	50 Å²	50	48.3 Å²	48.3	26%	0.262	29%	0.287	S	S	.	.	H	α-helix	trans	-67.8	-40.3	176.7	-176.5	65.8	0	0	0	110.5	R29 S32 L37 A38 V39 L202	R29-L35 WeakPolarHBondContact O-CD2 3.3Å; S32-L35 PolarHBondContact O-N 3.43Å; S32-L35 VanDerWaalsContact OG-CB 3.29Å; S32-L35 WeakPolarHBondContact OG-CB 3.41Å; S32-L35 PolarHBondContact OG-N 3.41Å; L35-L37 VanDerWaalsContact C-N 3.29Å; L35-L37 PolarHBondContact O-N 3.42Å; L35-A38 PolarHBondContact O-N 2.9Å; L35-V39 WeakPolarHBondContact O-CG2 3.38Å; L35-V39 PolarHBondContact O-N 2.88Å; L35-L202 HydrophobicContact CD1-CD2 3.77Å
36	S	89.6	Confident	81.2	Confident	61 Å²	61	45.7 Å²	45.7	43%	0.427	26%	0.264	S	S	.	.	H	α-helix	trans	-60.5	-39.5	174.1	-172	0	0	0	0	112	S32 A33 L40	S32-S36 PolarHBondContact O-N 2.97Å; A33-S36 PolarHBondContact O-N 2.97Å; S36-L40 WeakPolarHBondContact O-CB 3.49Å; S36-L40 WeakPolarHBondContact O-CG 3.33Å; S36-L40 PolarHBondContact O-N 3.44Å
37	L	91	Very high	83	Confident	6 Å²	6	42.5 Å²	42.5	3%	0.031	25%	0.245	C	C	.	.	H	α-helix	trans	-63	-45.7	173.7	-179.4	62.6	0	0	0	111.3	A33 R34 L35 V39 L40 M41 M186 W187 W190 W245 V249	A33-L37 PolarHBondContact O-N 2.77Å; R34-L37 WeakPolarHBondContact O-CB 3.31Å; R34-L37 PolarHBondContact O-N 3.29Å; L35-L37 VanDerWaalsContact C-N 3.29Å; L35-L37 PolarHBondContact O-N 3.42Å; L37-V39 PolarHBondContact O-N 3.39Å; L37-L40 PolarHBondContact O-N 3.21Å; L37-M41 HydrophobicContact CD1-CE 3.96Å; L37-M41 HydrophobicContact CD1-CG 4.42Å; L37-M41 HydrophobicContact CD2-CE 4.17Å; L37-M41 HydrophobicContact CG-CE 3.99Å; L37-M41 HydrophobicContact CG-SD 4.36Å; L37-M41 WeakPolarHBondContact O-CB 3.3Å; L37-M41 WeakPolarHBondContact O-CG 3.38Å; L37-M41 PolarHBondContact O-N 3.41Å; L37-M186 HydrophobicContact CD1-CE 3.93Å; L37-M186 HydrophobicContact CD2-CE 4.17Å; L37-W187 HydrophobicContact CB-CH2 4.43Å; L37-W187 HydrophobicContact CD2-CH2 4.2Å; L37-W187 HydrophobicContact CD2-CZ3 4.27Å; L37-W187 HydrophobicContact CG-CH2 4.23Å; L37-W190 HydrophobicContact CD2-CB 3.91Å; L37-W190 HydrophobicContact CD2-CD2 3.52Å; L37-W190 HydrophobicContact CD2-CE3 3.8Å; L37-W190 HydrophobicContact CD2-CG 3.57Å; L37-W245 HydrophobicContact CD1-CH2 4.05Å; L37-W245 HydrophobicContact CD1-CZ3 4.1Å; L37-V249 HydrophobicContact CD1-CB 4.31Å; L37-V249 HydrophobicContact CD1-CG1 3.57Å; L37-V249 HydrophobicContact CD1-CG2 3.78Å
38	A	91	Very high	84.8	Confident	0 Å²	0	42 Å²	42	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-61.8	-40.5	178	0	0	0	0	0	112.8	R34 L35 M41 F42 W187 L199 L202	R34-A38 PolarHBondContact O-N 3.28Å; L35-A38 PolarHBondContact O-N 2.9Å; A38-M41 PolarHBondContact O-N 3.11Å; A38-F42 WeakPolarHBondContact O-CB 3.28Å; A38-F42 PolarHBondContact O-N 2.84Å; A38-W187 HydrophobicContact CB-CH2 3.75Å; A38-W187 HydrophobicContact CB-CZ2 3.76Å; A38-L199 HydrophobicContact CB-CD2 3.89Å; A38-L202 HydrophobicContact CB-CD2 3.86Å; A38-L202 HydrophobicContact CB-CG 4.34Å
39	V	92.1	Very high	86.3	Confident	67 Å²	67	39.3 Å²	39.3	41%	0.406	22%	0.219	S	C	.	.	H	α-helix	trans	-67.5	-41.8	176.1	172.7	0	0	0	0	111.2	L35 L37 F42 L43	L35-V39 WeakPolarHBondContact O-CG2 3.38Å; L35-V39 PolarHBondContact O-N 2.88Å; L37-V39 PolarHBondContact O-N 3.39Å; V39-F42 WeakPolarHBondContact O-CB 3.47Å; V39-F42 PolarHBondContact O-N 3.21Å; V39-L43 HydrophobicContact CG1-CD1 4.41Å; V39-L43 WeakPolarHBondContact O-CG 3.49Å; V39-L43 PolarHBondContact O-N 3.14Å
40	L	93.1	Very high	87.7	Confident	16 Å²	16	31.6 Å²	31.6	8%	0.084	19%	0.192	C	C	.	.	H	α-helix	trans	-64.5	-39.9	175.3	-80.1	167.1	0	0	0	112.2	S36 L37 L43 G44 W241 F244 W245 L248 V249	S36-L40 WeakPolarHBondContact O-CB 3.49Å; S36-L40 WeakPolarHBondContact O-CG 3.33Å; S36-L40 PolarHBondContact O-N 3.44Å; L37-L40 PolarHBondContact O-N 3.21Å; L40-L43 PolarHBondContact O-N 3.34Å; L40-G44 PolarHBondContact O-N 3.14Å; L40-W241 PolarHBondContact O-NE1 3.31Å; L40-F244 HydrophobicContact CD2-CB 4.49Å; L40-W245 HydrophobicContact CB-CE3 4.45Å; L40-W245 HydrophobicContact CB-CZ3 4.43Å; L40-L248 HydrophobicContact CD1-CB 3.64Å; L40-L248 HydrophobicContact CD1-CD1 3.83Å; L40-L248 HydrophobicContact CD1-CG 4.39Å; L40-L248 HydrophobicContact CD2-CD1 4.21Å; L40-V249 HydrophobicContact CD1-CG2 3.81Å
41	M	93.4	Very high	89.4	Confident	1 Å²	1	26.8 Å²	26.8	1%	0.005	16%	0.16	C	C	.	.	H	α-helix	trans	-64.4	-44.6	172.8	-75.2	-176.5	174.5	0	0	111.5	L37 A38 L43 G44 I45 M183 M186 W187 W245	L37-M41 HydrophobicContact CD1-CE 3.96Å; L37-M41 HydrophobicContact CD1-CG 4.42Å; L37-M41 HydrophobicContact CD2-CE 4.17Å; L37-M41 HydrophobicContact CG-CE 3.99Å; L37-M41 HydrophobicContact CG-SD 4.36Å; L37-M41 WeakPolarHBondContact O-CB 3.3Å; L37-M41 WeakPolarHBondContact O-CG 3.38Å; L37-M41 PolarHBondContact O-N 3.41Å; A38-M41 PolarHBondContact O-N 3.11Å; M41-L43 VanDerWaalsContact C-N 3.35Å; M41-L43 PolarHBondContact O-N 3.34Å; M41-G44 PolarHBondContact O-N 3.08Å; M41-G44 VanDerWaalsContact O-N 3.11Å; M41-I45 WeakPolarHBondContact O-CG1 3.38Å; M41-I45 PolarHBondContact O-N 2.87Å; M41-M183 HydrophobicContact CE-CG 4.48Å; M41-M183 HydrophobicContact SD-CG 3.77Å; M41-M186 HydrophobicContact CE-CB 3.51Å; M41-M186 HydrophobicContact CE-CE 3.85Å; M41-M186 HydrophobicContact CE-CG 4.03Å; M41-M186 HydrophobicContact CE-SD 3.44Å; M41-M186 WeakPolarHBondContact CE-SD 3.33Å; M41-W187 VanDerWaalsContact SD-CE2 3.57Å; M41-W187 HydrophobicContact SD-CZ2 3.61Å; M41-W187 PolarHBondContact SD-NE1 3.2Å; M41-W245 HydrophobicContact CE-CH2 4.03Å; M41-W245 HydrophobicContact CG-CH2 4.04Å; M41-W245 HydrophobicContact CG-CZ3 3.97Å
42	F	94	Very high	90.4	Very high	38 Å²	38	21.7 Å²	21.7	17%	0.167	12%	0.122	C	C	.	.	H	α-helix	trans	-52.9	-52.7	173.8	169.6	-89.4	0	0	0	110.7	A38 V39 G44 I45 S46 L202 S205 G206 F209	A38-F42 WeakPolarHBondContact O-CB 3.28Å; A38-F42 PolarHBondContact O-N 2.84Å; V39-F42 WeakPolarHBondContact O-CB 3.47Å; V39-F42 PolarHBondContact O-N 3.21Å; F42-G44 VanDerWaalsContact C-N 3.3Å; F42-G44 PolarHBondContact O-N 2.87Å; F42-I45 PolarHBondContact O-N 2.95Å; F42-S46 WeakPolarHBondContact O-CB 3.46Å; F42-S46 PolarHBondContact O-N 2.77Å; F42-S46 PolarHBondContact O-OG 3.15Å; F42-L202 VanDerWaalsContact CD2-O 3.29Å; F42-L202 WeakPolarHBondContact CD2-O 3.33Å; F42-S205 WeakPolarHBondContact CD2-OG 3.49Å; F42-S205 WeakPolarHBondContact CE2-OG 3.44Å; F42-G206 VanDerWaalsContact CE2-CA 3.42Å; F42-G206 WeakPolarHBondContact O-CA 3.44Å; F42-F209 AromaticContact CE1-CD1 3.86Å; F42-F209 HydrophobicContact CE1-CD1 3.86Å; F42-F209 HydrophobicContact CE1-CE1 4.25Å; F42-F209 HydrophobicContact CE1-CG 4.26Å; F42-F209 HydrophobicContact CE2-CB 4.02Å; F42-F209 HydrophobicContact CE2-CG 4.4Å; F42-F209 HydrophobicContact CZ-CB 3.67Å; F42-F209 AromaticContact CZ-CD1 3.63Å; F42-F209 HydrophobicContact CZ-CD1 3.63Å; F42-F209 HydrophobicContact CZ-CD2 4.21Å; F42-F209 HydrophobicContact CZ-CE1 4.33Å; F42-F209 AromaticContact CZ-CG 3.56Å; F42-F209 HydrophobicContact CZ-CG 3.56Å
43	L	93.9	Very high	90.6	Very high	78 Å²	78	21.5 Å²	21.5	41%	0.408	12%	0.121	S	C	.	.	H	α-helix	trans	-61.6	-38.1	177.8	-68.6	174.8	0	0	0	112.2	V39 L40 M41 S46 V47	V39-L43 HydrophobicContact CG1-CD1 4.41Å; V39-L43 WeakPolarHBondContact O-CG 3.49Å; V39-L43 PolarHBondContact O-N 3.14Å; L40-L43 PolarHBondContact O-N 3.34Å; M41-L43 VanDerWaalsContact C-N 3.35Å; M41-L43 PolarHBondContact O-N 3.34Å; L43-S46 WeakPolarHBondContact O-CB 3.32Å; L43-S46 PolarHBondContact O-N 3.37Å; L43-V47 WeakPolarHBondContact O-CG2 3.05Å; L43-V47 PolarHBondContact O-N 2.78Å
44	G	93.6	Very high	90.9	Very high	2 Å²	2	20.9 Å²	20.9	2%	0.021	12%	0.116	C	C	.	.	H	α-helix	trans	-64.4	-48.9	178	0	0	0	0	0	112	L40 M41 F42 S46 V47 V48 W241	L40-G44 PolarHBondContact O-N 3.14Å; M41-G44 PolarHBondContact O-N 3.08Å; M41-G44 VanDerWaalsContact O-N 3.11Å; F42-G44 VanDerWaalsContact C-N 3.3Å; F42-G44 PolarHBondContact O-N 2.87Å; G44-S46 VanDerWaalsContact C-N 3.27Å; G44-S46 PolarHBondContact O-N 3.45Å; G44-V47 PolarHBondContact O-N 3.22Å; G44-V48 WeakPolarHBondContact O-CB 3.48Å; G44-V48 WeakPolarHBondContact O-CG2 3.19Å; G44-V48 PolarHBondContact O-N 3.26Å; G44-W241 VanDerWaalsContact CA-NE1 3.27Å; G44-W241 VanDerWaalsContact N-NE1 3.12Å
45	I	92.7	Very high	90.9	Very high	4 Å²	4	21 Å²	21	2%	0.021	12%	0.117	C	C	.	.	H	α-helix	trans	-64.5	-34	175.9	-59.5	-60.6	0	0	0	110.7	M41 F42 V48 Y49 F180 M183	M41-I45 WeakPolarHBondContact O-CG1 3.38Å; M41-I45 PolarHBondContact O-N 2.87Å; F42-I45 PolarHBondContact O-N 2.95Å; I45-V48 WeakPolarHBondContact O-CB 3.39Å; I45-V48 PolarHBondContact O-N 3.46Å; I45-Y49 HydrophobicContact CG2-CD2 3.93Å; I45-Y49 HydrophobicContact CG2-CE2 4.02Å; I45-Y49 WeakPolarHBondContact O-CD2 3.44Å; I45-Y49 PolarHBondContact O-N 3.2Å; I45-F180 HydrophobicContact CG2-CZ 4.41Å; I45-M183 HydrophobicContact CD1-SD 4.3Å; I45-M183 HydrophobicContact CG1-SD 4.11Å
46	S	92.2	Very high	90.9	Very high	11 Å²	11	18.8 Å²	18.8	8%	0.077	11%	0.105	C	C	.	.	H	α-helix	trans	-62.7	-45.1	172.5	-61.9	0	0	0	0	112.9	F42 L43 G44 Y49 G50 G206 G210	F42-S46 WeakPolarHBondContact O-CB 3.46Å; F42-S46 PolarHBondContact O-N 2.77Å; F42-S46 PolarHBondContact O-OG 3.15Å; L43-S46 WeakPolarHBondContact O-CB 3.32Å; L43-S46 PolarHBondContact O-N 3.37Å; G44-S46 VanDerWaalsContact C-N 3.27Å; G44-S46 PolarHBondContact O-N 3.45Å; S46-Y49 PolarHBondContact O-N 2.95Å; S46-G50 PolarHBondContact O-N 2.77Å; S46-G206 WeakPolarHBondContact CA-O 3.26Å; S46-G206 WeakPolarHBondContact CB-O 3.42Å; S46-G206 PolarHBondContact N-O 3.42Å; S46-G206 VanDerWaalsContact OG-CA 3.28Å; S46-G206 WeakPolarHBondContact OG-CA 3.4Å; S46-G206 PolarHBondContact OG-O 3.02Å; S46-G210 WeakPolarHBondContact O-CA 3.38Å
47	V	93.1	Very high	90.8	Very high	31 Å²	31	15.9 Å²	15.9	19%	0.188	9%	0.085	C	C	.	.	H	α-helix	trans	-63.1	-48.1	175.9	169.1	0	0	0	0	110.7	L43 G44 Y49 G50 L51	L43-V47 WeakPolarHBondContact O-CG2 3.05Å; L43-V47 PolarHBondContact O-N 2.78Å; G44-V47 PolarHBondContact O-N 3.22Å; V47-Y49 VanDerWaalsContact C-N 3.34Å; V47-Y49 PolarHBondContact O-N 3.1Å; V47-G50 CarbonylContact O-C 3.42Å; V47-G50 WeakPolarHBondContact O-CA 3.4Å; V47-G50 PolarHBondContact O-N 3.35Å; V47-L51 HydrophobicContact CG1-CD1 4.02Å; V47-L51 HydrophobicContact CG1-CG 4.17Å; V47-L51 WeakPolarHBondContact O-CG 3.36Å; V47-L51 PolarHBondContact O-N 3.39Å
48	V	92.3	Very high	90.7	Very high	1 Å²	1	15.6 Å²	15.6	1%	0.006	8%	0.084	C	C	.	.	H	α-helix	trans	-50.1	-51.6	176	157.4	0	0	0	0	111.4	G44 I45 G50 L51 R52 V144 E176 T179	G44-V48 WeakPolarHBondContact O-CB 3.48Å; G44-V48 WeakPolarHBondContact O-CG2 3.19Å; G44-V48 PolarHBondContact O-N 3.26Å; I45-V48 WeakPolarHBondContact O-CB 3.39Å; I45-V48 PolarHBondContact O-N 3.46Å; V48-G50 VanDerWaalsContact C-N 3.3Å; V48-G50 PolarHBondContact O-N 3.39Å; V48-L51 PolarHBondContact O-N 3.42Å; V48-R52 PolarHBondContact O-N 2.92Å; V48-R52 VanDerWaalsContact O-N 3.09Å; V48-V144 HydrophobicContact CG2-CG1 4.37Å; V48-V144 HydrophobicContact CG2-CG2 3.57Å; V48-E176 HydrophobicContact CG1-CG 3.58Å; V48-E176 WeakPolarHBondContact CG1-OE1 3.23Å; V48-E176 HydrophobicContact CG2-CG 4.47Å; V48-T179 HydrophobicContact CG2-CG2 4.2Å
49	Y	88.4	Confident	90.6	Very high	38 Å²	38	15.6 Å²	15.6	15%	0.149	8%	0.084	C	C	.	.	H	α-helix	trans	-65.1	-35.1	176.3	-90.4	-105.8	0	0	0	112.6	I45 S46 V47 R52 V53 F180 G207 A211	I45-Y49 HydrophobicContact CG2-CD2 3.93Å; I45-Y49 HydrophobicContact CG2-CE2 4.02Å; I45-Y49 WeakPolarHBondContact O-CD2 3.44Å; I45-Y49 PolarHBondContact O-N 3.2Å; S46-Y49 PolarHBondContact O-N 2.95Å; V47-Y49 VanDerWaalsContact C-N 3.34Å; V47-Y49 PolarHBondContact O-N 3.1Å; Y49-R52 PolarHBondContact O-N 2.88Å; Y49-V53 WeakPolarHBondContact O-CG1 3.17Å; Y49-V53 WeakPolarHBondContact O-CG2 3.32Å; Y49-V53 PolarHBondContact O-N 2.96Å; Y49-F180 AromaticContact CE2-CE2 3.8Å; Y49-F180 HydrophobicContact CE2-CE2 3.8Å; Y49-F180 AromaticContact CE2-CZ 3.65Å; Y49-F180 HydrophobicContact CE2-CZ 3.65Å; Y49-G207 WeakPolarHBondContact CB-O 3.4Å; Y49-G207 WeakPolarHBondContact CD1-O 3.39Å; Y49-A211 HydrophobicContact CD1-CB 4.39Å
50	G	89.6	Confident	90.3	Very high	6 Å²	6	12.8 Å²	12.8	6%	0.062	7%	0.066	C	C	.	.	H	α-helix	trans	-62.5	-41.3	173.2	0	0	0	0	0	113.5	S46 V47 V48 R52 N54 A214	S46-G50 PolarHBondContact O-N 2.77Å; V47-G50 CarbonylContact O-C 3.42Å; V47-G50 WeakPolarHBondContact O-CA 3.4Å; V47-G50 PolarHBondContact O-N 3.35Å; V48-G50 VanDerWaalsContact C-N 3.3Å; V48-G50 PolarHBondContact O-N 3.39Å; G50-R52 VanDerWaalsContact C-N 3.26Å; G50-R52 PolarHBondContact O-N 2.94Å; G50-N54 WeakPolarHBondContact O-CB 3.29Å; G50-N54 PolarHBondContact O-N 3.13Å; G50-A214 VanDerWaalsContact CA-CB 3.49Å
51	L	89.6	Confident	89.9	Confident	2 Å²	2	12 Å²	12	1%	0.01	6%	0.062	C	C	.	.	H	α-helix	trans	-64.5	-31.9	175.1	-63.7	172.7	0	0	0	111.9	V47 V48 N54 T147 A148 T151 C234	V47-L51 HydrophobicContact CG1-CD1 4.02Å; V47-L51 HydrophobicContact CG1-CG 4.17Å; V47-L51 WeakPolarHBondContact O-CG 3.36Å; V47-L51 PolarHBondContact O-N 3.39Å; V48-L51 PolarHBondContact O-N 3.42Å; L51-N54 PolarHBondContact O-ND2 3.15Å; L51-N54 VanDerWaalsContact O-ND2 3.15Å; L51-N54 PolarHBondContact O-OD1 2.84Å; L51-T147 HydrophobicContact CB-CG2 4.45Å; L51-T147 HydrophobicContact CD1-CG2 4.01Å; L51-A148 HydrophobicContact CD1-CB 4.29Å; L51-T151 HydrophobicContact CD2-CG2 3.77Å; L51-C234 HydrophobicContact CD2-CB 3.9Å
52	R	87.8	Confident	89.6	Confident	21 Å²	21	12 Å²	12	8%	0.079	6%	0.062	C	C	.	.	H	α-helix	trans	-75.6	-48.2	178.3	-173.1	-173.7	-61.2	-165.8	-4.6	113.3	V48 Y49 G50 F116 E176	V48-R52 PolarHBondContact O-N 2.92Å; V48-R52 VanDerWaalsContact O-N 3.09Å; Y49-R52 PolarHBondContact O-N 2.88Å; G50-R52 VanDerWaalsContact C-N 3.26Å; G50-R52 PolarHBondContact O-N 2.94Å; R52-F116 HydrophobicContact CB-CZ 4.47Å; R52-F116 HydrophobicContact CG-CD1 4.19Å; R52-F116 HydrophobicContact CG-CE1 3.92Å; R52-F116 HydrophobicContact CG-CE2 4.44Å; R52-F116 HydrophobicContact CG-CZ 4.06Å; R52-F116 VanDerWaalsContact NE-CE1 3.33Å; R52-E176 IonicContact CZ-OE1 2.91Å; R52-E176 VanDerWaalsContact CZ-OE1 3.26Å; R52-E176 IonicContact NE-OE1 3.03Å; R52-E176 PolarHBondContact NE-OE1 3.36Å; R52-E176 IonicContact NH2-OE1 3.29Å; R52-E176 PolarHBondContact NH2-OE1 2.98Å
53	V	86.8	Confident	89.1	Confident	4 Å²	4	10.9 Å²	10.9	2%	0.024	6%	0.058	C	C	.	.	H	α-helix	trans	-84.2	-14.1	-171.7	-56.2	0	0	0	0	113.6	Y49 L55 S56 A211 A214 L215 L311	Y49-V53 WeakPolarHBondContact O-CG1 3.17Å; Y49-V53 WeakPolarHBondContact O-CG2 3.32Å; Y49-V53 PolarHBondContact O-N 2.96Å; V53-L55 PolarHBondContact O-N 2.77Å; V53-S56 PolarHBondContact O-N 2.87Å; V53-S56 PolarHBondContact O-OG 3.43Å; V53-A211 HydrophobicContact CG1-CB 4.39Å; V53-A214 HydrophobicContact CG2-CB 3.54Å; V53-L215 HydrophobicContact CB-CD2 4.07Å; V53-L215 HydrophobicContact CB-CG 4.48Å; V53-L215 HydrophobicContact CG2-CD2 4.17Å; V53-L215 HydrophobicContact CG2-CG 4.19Å; V53-L311 HydrophobicContact CG1-CD1 3.96Å; V53-L311 HydrophobicContact CG1-CD2 4.34Å; V53-L311 HydrophobicContact CG1-CG 4.26Å
54	N	88.9	Confident	88.2	Confident	0 Å²	0	10 Å²	10	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-56.5	-35	-179	60.1	17.6	0	0	0	113	G50 L51 A58 V230 F231	G50-N54 WeakPolarHBondContact O-CB 3.29Å; G50-N54 PolarHBondContact O-N 3.13Å; L51-N54 PolarHBondContact O-ND2 3.15Å; L51-N54 VanDerWaalsContact O-ND2 3.15Å; L51-N54 PolarHBondContact O-OD1 2.84Å; N54-A58 WeakPolarHBondContact O-CB 3.18Å; N54-A58 PolarHBondContact O-N 3.44Å; N54-V230 HydrophobicContact CB-CG1 3.79Å; N54-F231 HydrophobicContact CB-CE1 4.38Å; N54-F231 WeakPolarHBondContact OD1-CE1 3.33Å
55	L	89.9	Confident	86.7	Confident	4 Å²	4	14.5 Å²	14.5	2%	0.021	8%	0.081	C	C	.	.	H	α-helix	trans	-73.3	-31.6	-176.2	-175.2	70.8	0	0	0	112.5	V53 V57 A58 M59 M62 L113 R169 F231	V53-L55 PolarHBondContact O-N 2.77Å; L55-V57 VanDerWaalsContact C-N 3.3Å; L55-V57 PolarHBondContact O-N 3.4Å; L55-A58 PolarHBondContact O-N 2.9Å; L55-M59 HydrophobicContact CD1-CE 3.57Å; L55-M59 HydrophobicContact CG-CE 4.2Å; L55-M59 WeakPolarHBondContact O-CA 3.4Å; L55-M59 WeakPolarHBondContact O-CB 3.09Å; L55-M59 PolarHBondContact O-N 3.32Å; L55-M62 HydrophobicContact CD1-SD 4.01Å; L55-L113 HydrophobicContact CD2-CD2 4.08Å; L55-L113 HydrophobicContact CG-CD2 4.07Å; L55-R169 HydrophobicContact CD2-CG 4.45Å; L55-F231 HydrophobicContact CD1-CE1 4.49Å; L55-F231 HydrophobicContact CD1-CZ 3.86Å
56	S	86.4	Confident	84.4	Confident	4 Å²	4	19.6 Å²	19.6	3%	0.028	11%	0.112	C	C	.	.	H	α-helix	trans	-63.3	-39.5	-179.5	57.9	0	0	0	0	111.8	V53 L311 T312	V53-S56 PolarHBondContact O-N 2.87Å; V53-S56 PolarHBondContact O-OG 3.43Å; S56-L311 PolarHBondContact OG-O 2.88Å; S56-T312 VanDerWaalsContact CB-O 3.22Å; S56-T312 WeakPolarHBondContact CB-O 3.36Å
57	V	86.9	Confident	81.7	Confident	0 Å²	0	24.4 Å²	24.4	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-80.3	-41.5	174.5	-178.8	0	0	0	0	111.4	L55 M59 V60 L215 T218 P315 L326	L55-V57 VanDerWaalsContact C-N 3.3Å; L55-V57 PolarHBondContact O-N 3.4Å; V57-M59 PolarHBondContact O-N 3.5Å; V57-V60 WeakPolarHBondContact O-CB 3.29Å; V57-V60 PolarHBondContact O-N 3.09Å; V57-L215 HydrophobicContact CG2-CD2 3.52Å; V57-T218 HydrophobicContact CB-CG2 3.67Å; V57-T218 HydrophobicContact CG1-CG2 3.8Å; V57-P315 HydrophobicContact CG2-CB 4.07Å; V57-P315 HydrophobicContact CG2-CG 3.82Å; V57-L326 HydrophobicContact CG1-CD1 4.24Å
58	A	88.5	Confident	79.2	Confident	0 Å²	0	28.4 Å²	28.4	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-64.3	-29.6	178.5	0	0	0	0	0	112.4	N54 L55 V60 A61 M62 F231	N54-A58 WeakPolarHBondContact O-CB 3.18Å; N54-A58 PolarHBondContact O-N 3.44Å; L55-A58 PolarHBondContact O-N 2.9Å; A58-V60 VanDerWaalsContact C-N 3.29Å; A58-V60 PolarHBondContact O-N 2.61Å; A58-A61 CarbonylContact O-C 3.51Å; A58-A61 WeakPolarHBondContact O-CA 3.3Å; A58-A61 WeakPolarHBondContact O-CB 3.41Å; A58-A61 PolarHBondContact O-N 2.68Å; A58-M62 HydrophobicContact CB-SD 4.32Å; A58-M62 VanDerWaalsContact O-CG 3.22Å; A58-M62 WeakPolarHBondContact O-CG 3.42Å; A58-M62 PolarHBondContact O-N 3.23Å; A58-F231 HydrophobicContact CB-CE2 4.08Å; A58-F231 HydrophobicContact CB-CZ 3.81Å
59	M	89.3	Confident	76.4	Confident	0 Å²	0	32.8 Å²	32.8	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-58.5	-42.3	179.1	-166.8	91.5	-43.5	0	0	111.8	L55 V57 A61 M62 V63 W104 Q109 L112	L55-M59 HydrophobicContact CD1-CE 3.57Å; L55-M59 HydrophobicContact CG-CE 4.2Å; L55-M59 WeakPolarHBondContact O-CA 3.4Å; L55-M59 WeakPolarHBondContact O-CB 3.09Å; L55-M59 PolarHBondContact O-N 3.32Å; V57-M59 PolarHBondContact O-N 3.5Å; M59-A61 PolarHBondContact O-N 2.94Å; M59-M62 HydrophobicContact CE-CB 4.17Å; M59-M62 HydrophobicContact CE-CE 4.25Å; M59-M62 HydrophobicContact CE-SD 3.62Å; M59-M62 PolarHBondContact O-N 3.34Å; M59-V63 HydrophobicContact CG-CG2 4.2Å; M59-V63 WeakPolarHBondContact O-CG2 3.19Å; M59-V63 PolarHBondContact O-N 3.04Å; M59-V63 VanDerWaalsContact O-N 3.16Å; M59-W104 HydrophobicContact CE-CE3 4Å; M59-W104 HydrophobicContact CE-CZ3 3.6Å; M59-W104 HydrophobicContact SD-CE3 4.29Å; M59-W104 HydrophobicContact SD-CZ3 4.47Å; M59-Q109 HydrophobicContact CG-CB 4.35Å; M59-Q109 HydrophobicContact CG-CG 4.08Å; M59-Q109 HydrophobicContact SD-CB 4.17Å; M59-Q109 HydrophobicContact SD-CG 4Å; M59-L112 HydrophobicContact SD-CD1 4.42Å
60	V	85.7	Confident	73.8	Confident	7 Å²	7	33.8 Å²	33.8	4%	0.042	22%	0.217	C	C	.	.	H	α-helix	trans	-55.8	-35.2	174.6	178.8	0	0	0	0	111.5	V57 A58 L93 P315 N319 L326	V57-V60 WeakPolarHBondContact O-CB 3.29Å; V57-V60 PolarHBondContact O-N 3.09Å; A58-V60 VanDerWaalsContact C-N 3.29Å; A58-V60 PolarHBondContact O-N 2.61Å; V60-L93 HydrophobicContact CG1-CD2 4.35Å; V60-P315 HydrophobicContact CG2-CB 4.21Å; V60-N319 HydrophobicContact CG1-CB 3.54Å; V60-N319 WeakPolarHBondContact CG1-OD1 3.46Å; V60-N319 HydrophobicContact CG2-CB 4.33Å; V60-L326 HydrophobicContact CB-CD1 4.19Å; V60-L326 HydrophobicContact CG1-CD1 4.05Å
61	A	85.1	Confident	71.1	Confident	0 Å²	0	38.1 Å²	38.1	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-89.4	-13.6	-179.7	0	0	0	0	0	114.1	A58 M59 Q95 C222 W227 L326	A58-A61 CarbonylContact O-C 3.51Å; A58-A61 WeakPolarHBondContact O-CA 3.3Å; A58-A61 WeakPolarHBondContact O-CB 3.41Å; A58-A61 PolarHBondContact O-N 2.68Å; M59-A61 PolarHBondContact O-N 2.94Å; A61-Q95 PolarHBondContact O-NE2 2.93Å; A61-Q95 PolarHBondContact O-OE1 2.81Å; A61-C222 HydrophobicContact CB-CB 4.33Å; A61-W227 HydrophobicContact CB-CB 4.22Å; A61-L326 HydrophobicContact CB-CD1 4.39Å; A61-L326 HydrophobicContact CB-CD2 3.8Å
62	M	86.5	Confident	68.5	Low	0 Å²	0	47.7 Å²	47.7	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-94.2	-21.4	-178.7	-74	173.1	79.7	0	0	112.5	L55 A58 M59 Q101 Y102 W104 A158 L165 W227 F231	L55-M62 HydrophobicContact CD1-SD 4.01Å; A58-M62 HydrophobicContact CB-SD 4.32Å; A58-M62 VanDerWaalsContact O-CG 3.22Å; A58-M62 WeakPolarHBondContact O-CG 3.42Å; A58-M62 PolarHBondContact O-N 3.23Å; M59-M62 HydrophobicContact CE-CB 4.17Å; M59-M62 HydrophobicContact CE-CE 4.25Å; M59-M62 HydrophobicContact CE-SD 3.62Å; M59-M62 PolarHBondContact O-N 3.34Å; M62-Q101 CarbonylContact O-C 3.58Å; M62-Q101 WeakPolarHBondContact O-CA 3.46Å; M62-Y102 HydrophobicContact CE-CD2 4.5Å; M62-Y102 HydrophobicContact CE-CE2 4.28Å; M62-Y102 PolarHBondContact O-N 3.29Å; M62-W104 HydrophobicContact CB-CZ3 4.03Å; M62-W104 HydrophobicContact CE-CH2 3.55Å; M62-W104 HydrophobicContact CE-CZ3 3.59Å; M62-W104 HydrophobicContact SD-CZ3 4.41Å; M62-A158 HydrophobicContact CE-CB 3.73Å; M62-L165 HydrophobicContact CE-CD2 4.24Å; M62-W227 HydrophobicContact CE-CD2 4.46Å; M62-W227 HydrophobicContact CE-CE3 4.1Å; M62-W227 HydrophobicContact CE-CH2 3.86Å; M62-W227 HydrophobicContact CE-CZ2 4.22Å; M62-W227 HydrophobicContact CE-CZ3 3.77Å; M62-W227 HydrophobicContact CG-CB 4.26Å; M62-W227 HydrophobicContact CG-CD2 3.51Å; M62-W227 HydrophobicContact CG-CE3 3.89Å; M62-W227 HydrophobicContact CG-CG 3.67Å; M62-W227 HydrophobicContact CG-CZ2 4.37Å; M62-W227 HydrophobicContact CG-CZ3 4.46Å; M62-W227 HydrophobicContact SD-CD2 4.25Å; M62-W227 HydrophobicContact SD-CE3 4Å; M62-W227 HydrophobicContact SD-CZ3 4.27Å; M62-F231 HydrophobicContact SD-CE2 4.08Å; M62-F231 HydrophobicContact SD-CZ 4.32Å
63	V	84.9	Confident	66	Low	15 Å²	15	55 Å²	55	9%	0.091	33%	0.328	C	S	.	.	B	Isolated β-bridge	trans	-94.2	135.3	-175.3	177.6	0	0	0	0	110.4	M59 V65 Y102 W104 Q109	M59-V63 HydrophobicContact CG-CG2 4.2Å; M59-V63 WeakPolarHBondContact O-CG2 3.19Å; M59-V63 PolarHBondContact O-N 3.04Å; M59-V63 VanDerWaalsContact O-N 3.16Å; V63-V65 PolarHBondContact O-N 3.13Å; V63-Y102 WeakPolarHBondContact CA-O 3.29Å; V63-W104 WeakPolarHBondContact CG1-O 3.19Å; V63-W104 HydrophobicContact CG2-CB 4.35Å; V63-W104 HydrophobicContact CG2-CE3 4.16Å; V63-Q109 HydrophobicContact CG2-CG 4Å
64	N	74.8	Confident	63.5	Low	59 Å²	59	59.2 Å²	59.2	32%	0.316	36%	0.355	S	S	.	.			trans	-81.9	114	173.3	-172.6	4.1	0	0	0	110.6	T66 Q101 Y102	N64-T66 VanDerWaalsContact C-N 3.26Å; N64-T66 PolarHBondContact ND2-OG1 3.17Å; N64-T66 PolarHBondContact O-N 3.25Å; N64-T66 WeakPolarHBondContact OD1-CB 3.21Å; N64-T66 PolarHBondContact OD1-N 3.1Å; N64-T66 PolarHBondContact OD1-OG1 3.31Å; N64-Q101 HydrophobicContact CB-CB 3.99Å; N64-Y102 PolarHBondContact N-O 3.41Å
65	V	61	Low	61.1	Low	98 Å²	98	66.7 Å²	66.7	59%	0.594	40%	0.4	S	S	*	.			trans	-82.7	0.3	179.3	-171.2	0	0	0	0	112.2	V63 D67	V63-V65 PolarHBondContact O-N 3.13Å; V65-D67 VanDerWaalsContact C-N 3.3Å; V65-D67 PolarHBondContact O-N 3.04Å
66	T	45.3	Very low	58.8	Low	110 Å²	110	68.4 Å²	68.4	68%	0.675	42%	0.415	S	S	*	.			trans	-82.1	11.7	-175.2	53.6	0	0	0	0	116.2	N64 P68	N64-T66 VanDerWaalsContact C-N 3.26Å; N64-T66 PolarHBondContact ND2-OG1 3.17Å; N64-T66 PolarHBondContact O-N 3.25Å; N64-T66 WeakPolarHBondContact OD1-CB 3.21Å; N64-T66 PolarHBondContact OD1-N 3.1Å; N64-T66 PolarHBondContact OD1-OG1 3.31Å; T66-P68 WeakPolarHBondContact O-CD 3.48Å
67	D	34.9	Very low	56.9	Low	113 Å²	113	73.3 Å²	73.3	60%	0.604	44%	0.437	S	S	*	.			trans	-105.4	90.8	173.2	-146.4	-3.6	0	0	0	112.5	V65 S69	V65-D67 VanDerWaalsContact C-N 3.3Å; V65-D67 PolarHBondContact O-N 3.04Å; D67-S69 VanDerWaalsContact CG-CB 3.44Å; D67-S69 PolarHBondContact O-N 2.77Å; D67-S69 WeakPolarHBondContact OD1-CB 3.46Å; D67-S69 PolarHBondContact OD1-N 2.89Å; D67-S69 PolarHBondContact OD2-OG 2.96Å
68	P	41.2	Very low	55.7	Low	114 Å²	114	78.4 Å²	78.4	74%	0.74	47%	0.47	S	S	*	.			trans	-75.4	53.4	157.3	34.9	-32	0	0	0	108.7	T66 G70	T66-P68 WeakPolarHBondContact O-CD 3.48Å; P68-G70 PolarHBondContact O-N 3.31Å
69	S	32.3	Very low	54.6	Low	93 Å²	93	79.8 Å²	79.8	65%	0.65	48%	0.482	S	S	*	.			trans	-73.3	81.7	173.9	49.6	0	0	0	0	109	D67	D67-S69 VanDerWaalsContact CG-CB 3.44Å; D67-S69 PolarHBondContact O-N 2.77Å; D67-S69 WeakPolarHBondContact OD1-CB 3.46Å; D67-S69 PolarHBondContact OD1-N 2.89Å; D67-S69 PolarHBondContact OD2-OG 2.96Å
70	G	33.9	Very low	53.4	Low	60 Å²	60	79.9 Å²	79.9	62%	0.619	48%	0.483	S	S	*	.			trans	121.5	74.1	172	0	0	0	0	0	112.3	P68 R72	P68-G70 PolarHBondContact O-N 3.31Å; G70-R72 PolarHBondContact O-N 3.25Å
71	A	34.4	Very low	52.4	Low	96 Å²	96	84.3 Å²	84.3	79%	0.793	51%	0.512	S	S	*	.			trans	-58.8	74.2	147.4	0	0	0	0	0	108.7	N73	A71-N73 PolarHBondContact O-N 3.29Å
72	R	35.1	Very low	51.2	Low	203 Å²	203	90.5 Å²	90.5	77%	0.766	54%	0.544	S	S	*	.			trans	-65.3	113.6	156.4	-92.3	-179.4	168.2	163.7	-0.8	104.2	G70 T74	G70-R72 PolarHBondContact O-N 3.25Å; R72-T74 PolarHBondContact O-N 3.27Å; R72-T74 PolarHBondContact O-OG1 3.3Å
73	N	33.5	Very low	49.5	Very low	174 Å²	174	94.7 Å²	94.7	93%	0.93	57%	0.571	S	S	*	*			trans	-52.7	79.2	166.9	-80.3	-22.4	0	0	0	109.4	A71	A71-N73 PolarHBondContact O-N 3.29Å
74	T	35.3	Very low	47.3	Very low	94 Å²	94	100.3 Å²	100.3	58%	0.577	61%	0.611	S	S	*	*			trans	-118	122.6	177.3	-20.9	0	0	0	0	105.2	R72 A76	R72-T74 PolarHBondContact O-N 3.27Å; R72-T74 PolarHBondContact O-OG1 3.3Å; T74-A76 PolarHBondContact O-N 3.34Å
75	T	37.8	Very low	45.6	Very low	156 Å²	156	99.9 Å²	99.9	96%	0.957	62%	0.621	S	S	*	*			trans	-66	36.5	174.2	38.9	0	0	0	0	112.4
76	A	41.3	Very low	44.7	Very low	40 Å²	40	101.7 Å²	101.7	33%	0.331	64%	0.635	S	S	.	*	P	Polyproline II helix	trans	-82.9	138	178.5	0	0	0	0	0	109.6	T74 P78 T454	T74-A76 PolarHBondContact O-N 3.34Å; A76-P78 WeakPolarHBondContact O-CD 3.26Å; A76-T454 HydrophobicContact CB-CG2 4.07Å
77	E	47.8	Very low	44.4	Very low	107 Å²	107	104 Å²	104	50%	0.5	64%	0.638	S	S	.	*	P	Polyproline II helix	trans	-55.3	119.8	173.9	-71.7	-175.6	147.9	0	0	109.3	R459	E77-R459 IonicContact OE2-CZ 3.85Å; E77-R459 VanDerWaalsContact OE2-CZ 3.23Å; E77-R459 IonicContact OE2-NH1 3.31Å; E77-R459 PolarHBondContact OE2-NH1 2.85Å; E77-R459 IonicContact OE2-NH2 2.88Å; E77-R459 PolarHBondContact OE2-NH2 2.7Å
78	P	60.9	Low	44.4	Very low	107 Å²	107	107.3 Å²	107.3	70%	0.695	66%	0.655	S	S	*	*	P	Polyproline II helix	trans	-65	162.7	178.4	26	-31.7	0	0	0	110.7	A76	A76-P78 WeakPolarHBondContact O-CD 3.26Å
79	A	65.6	Low	44.2	Very low	29 Å²	29	105.4 Å²	105.4	24%	0.24	65%	0.645	C	S	.	*	S	Bend	trans	-50.5	162.3	167.7	0	0	0	0	0	111.4	I321	A79-I321 HydrophobicContact CB-CD1 4.45Å
80	C	64.8	Low	44.5	Very low	2 Å²	2	106.3 Å²	106.3	1%	0.014	65%	0.651	C	S	.	*	P	Polyproline II helix	trans	-61.9	144.3	-175.1	-71	0	0	0	0	112	L82 I321 H323 C389	C80-L82 PolarHBondContact O-N 3.36Å; C80-I321 WeakPolarHBondContact CB-O 3.27Å; C80-I321 PolarHBondContact N-O 3.41Å; C80-H323 PolarHBondContact O-CD2 3.07Å; C80-H323 PolarHBondContact O-NE2 3.19Å; C80-C389 WeakPolarHBondContact CA-SG 3.12Å; C80-C389 HydrophobicContact CB-CB 3.64Å; C80-C389 WeakPolarHBondContact CB-SG 3.44Å; C80-C389 WeakPolarHBondContact SG-CA 3.36Å; C80-C389 WeakPolarHBondContact SG-CB 3.44Å; C80-C389 CovalentContact SG-SG 2.05Å; C80-C389 PolarHBondContact SG-SG 3.1Å
81	P	63.8	Low	45	Very low	101 Å²	101	113.4 Å²	113.4	66%	0.656	66%	0.659	S	S	*	*	P	Polyproline II helix	trans	-59.9	135.8	-179.3	23.8	-32	0	0	0	110.2
82	L	59.5	Low	45.7	Very low	129 Å²	129	112.3 Å²	112.3	68%	0.675	65%	0.65	S	S	*	*	P	Polyproline II helix	trans	-53.3	138.3	173.2	-71.9	163.3	0	0	0	109.6	C80 S84 H323	C80-L82 PolarHBondContact O-N 3.36Å; L82-S84 PolarHBondContact O-N 3.31Å; L82-H323 HydrophobicContact CD2-CB 3.92Å
83	P	51	Low	46.7	Very low	89 Å²	89	104.7 Å²	104.7	58%	0.578	63%	0.625	S	S	*	*	P	Polyproline II helix	trans	-58.3	125.4	-179.5	18.8	-28.2	0	0	0	110.8	G85	P83-G85 VanDerWaalsContact C-N 3.28Å; P83-G85 PolarHBondContact O-N 3.36Å
84	S	38.9	Very low	47.9	Very low	133 Å²	133	103.1 Å²	103.1	93%	0.93	61%	0.612	S	S	*	*			trans	-75.2	75.2	-179.2	29.9	0	0	0	0	111.4	L82	L82-S84 PolarHBondContact O-N 3.31Å
85	G	39	Very low	49.4	Very low	50 Å²	50	99.9 Å²	99.9	52%	0.515	59%	0.59	S	S	.	*			trans	-95.1	150.9	164.5	0	0	0	0	0	111.3	P83 E87	P83-G85 VanDerWaalsContact C-N 3.28Å; P83-G85 PolarHBondContact O-N 3.36Å; G85-E87 PolarHBondContact O-N 2.92Å
86	P	43.4	Very low	51.2	Low	136 Å²	136	94.9 Å²	94.9	88%	0.883	56%	0.56	S	S	*	*	S	Bend	trans	-82	63.8	-177.3	36	-34.6	0	0	0	111
87	E	37.3	Very low	52.3	Low	158 Å²	158	101.3 Å²	101.3	74%	0.738	59%	0.589	S	S	*	*			trans	-147.4	122.7	161.5	-73	-162.2	161.8	0	0	110.5	G85 S89	G85-E87 PolarHBondContact O-N 2.92Å; E87-S89 PolarHBondContact O-N 3.29Å
88	N	36.3	Very low	53.2	Low	182 Å²	182	100.1 Å²	100.1	97%	0.973	61%	0.606	S	S	*	*			trans	-67.7	50	167.3	-93.1	-11.8	0	0	0	111.6
89	S	36.5	Very low	54.1	Low	74 Å²	74	96.3 Å²	96.3	52%	0.517	58%	0.58	S	S	.	*			trans	-109.2	102.6	165.4	-61.2	0	0	0	0	104.8	E87 R91	E87-S89 PolarHBondContact O-N 3.29Å; S89-R91 PolarHBondContact O-N 3.43Å
90	S	39	Very low	54.8	Low	112 Å²	112	97.9 Å²	97.9	78%	0.783	59%	0.588	S	S	*	*			trans	-44.9	102.8	149.9	38	0	0	0	0	105.9	A92	S90-A92 PolarHBondContact O-N 2.95Å
91	R	42.9	Very low	55.7	Low	209 Å²	209	101.7 Å²	101.7	79%	0.789	61%	0.605	S	S	*	*			trans	-66.5	66.8	169.1	-87.3	-176.1	170.8	167	-3.8	106.5	S89 L93	S89-R91 PolarHBondContact O-N 3.43Å; R91-L93 PolarHBondContact O-N 3.21Å
92	A	49.1	Very low	56.8	Low	73 Å²	73	98.5 Å²	98.5	60%	0.603	58%	0.581	S	S	*	*			trans	-54.4	132.5	159.1	0	0	0	0	0	105.1	S90 Q94	S90-A92 PolarHBondContact O-N 2.95Å; A92-Q94 PolarHBondContact O-N 2.83Å
93	L	57.3	Low	58.1	Low	44 Å²	44	97.8 Å²	97.8	23%	0.23	58%	0.584	C	S	.	*			trans	-31.5	108.9	171.8	-87	139.1	0	0	0	109.7	V60 R91 Q95 L326	V60-L93 HydrophobicContact CG1-CD2 4.35Å; R91-L93 PolarHBondContact O-N 3.21Å; L93-Q95 VanDerWaalsContact C-N 3.29Å; L93-Q95 PolarHBondContact O-N 3.47Å; L93-L326 HydrophobicContact CD2-CB 4Å; L93-L326 HydrophobicContact CD2-CD1 4.03Å; L93-L326 HydrophobicContact CD2-CD2 4Å; L93-L326 HydrophobicContact CD2-CG 4.25Å
94	Q	59.3	Low	59.8	Low	141 Å²	141	94.5 Å²	94.5	66%	0.659	56%	0.56	S	S	*	*			trans	-67	93.9	179.4	-103.8	167.8	-30.8	0	0	106.9	A92 E223	A92-Q94 PolarHBondContact O-N 2.83Å; Q94-E223 HydrophobicContact CB-CG 4.09Å; Q94-E223 VanDerWaalsContact O-CA 3.32Å; Q94-E223 WeakPolarHBondContact O-CA 3.46Å; Q94-E223 VanDerWaalsContact O-CG 3.3Å; Q94-E223 WeakPolarHBondContact O-CG 3.46Å
95	Q	65.7	Low	62.1	Low	26 Å²	26	91.9 Å²	91.9	12%	0.121	54%	0.535	C	S	.	.			trans	-120.7	153.3	172	-67.9	-176.1	-49.5	0	0	108.2	A61 L93 D97	A61-Q95 PolarHBondContact O-NE2 2.93Å; A61-Q95 PolarHBondContact O-OE1 2.81Å; L93-Q95 VanDerWaalsContact C-N 3.29Å; L93-Q95 PolarHBondContact O-N 3.47Å; Q95-D97 PolarHBondContact O-N 2.96Å
96	P	75.7	Confident	64.2	Low	50 Å²	50	89.7 Å²	89.7	33%	0.325	51%	0.512	S	S	.	.			trans	-56.4	136.6	173.2	-22.5	33	0	0	0	111.4	G98 T99	P96-G98 PolarHBondContact O-N 3.44Å; P96-T99 WeakPolarHBondContact O-CB 3.5Å; P96-T99 PolarHBondContact O-N 3.18Å; P96-T99 PolarHBondContact O-OG1 2.98Å
97	D	64.9	Low	66.3	Low	175 Å²	175	87.5 Å²	87.5	94%	0.936	49%	0.49	S	S	*	.	T	Hydrogen-bonded Turn	trans	-53.6	129.3	177.3	-72.1	-34.5	0	0	0	110.9	Q95	Q95-D97 PolarHBondContact O-N 2.96Å
98	G	67.3	Low	68.8	Low	83 Å²	83	81.6 Å²	81.6	86%	0.856	47%	0.465	S	S	*	.	T	Hydrogen-bonded Turn	trans	94	4.9	-178.4	0	0	0	0	0	115.3	P96	P96-G98 PolarHBondContact O-N 3.44Å
99	T	79.4	Confident	71.3	Confident	27 Å²	27	73.6 Å²	73.6	17%	0.166	42%	0.422	C	S	.	.			trans	-68	123.9	170.8	-56.3	0	0	0	0	110.1	P96 W227	P96-T99 WeakPolarHBondContact O-CB 3.5Å; P96-T99 PolarHBondContact O-N 3.18Å; P96-T99 PolarHBondContact O-OG1 2.98Å; T99-W227 HydrophobicContact CG2-CG 4.29Å
100	P	80.1	Confident	73.7	Confident	61 Å²	61	70.2 Å²	70.2	40%	0.396	40%	0.399	S	S	.	.			trans	-68.7	134.4	-176.9	24.2	-31.4	0	0	0	111.7	W227	P100-W227 HydrophobicContact CG-CZ2 3.81Å; P100-W227 PolarHBondContact O-NE1 3.22Å
101	Q	84.4	Confident	76.3	Confident	82 Å²	82	69.5 Å²	69.5	38%	0.383	38%	0.379	S	S	.	.			trans	-120.6	146.5	173.6	-63.9	177.7	-3.1	0	0	109.8	M62 N64	M62-Q101 CarbonylContact O-C 3.58Å; M62-Q101 WeakPolarHBondContact O-CA 3.46Å; N64-Q101 HydrophobicContact CB-CB 3.99Å
102	Y	86.7	Confident	78.6	Confident	35 Å²	35	59.7 Å²	59.7	14%	0.137	34%	0.342	C	S	.	.	B	Isolated β-bridge	trans	-117.1	140.9	-174.1	-55.4	-76.6	0	0	0	111.5	M62 V63 N64 W104 A158 G159 W227	M62-Y102 HydrophobicContact CE-CD2 4.5Å; M62-Y102 HydrophobicContact CE-CE2 4.28Å; M62-Y102 PolarHBondContact O-N 3.29Å; V63-Y102 WeakPolarHBondContact CA-O 3.29Å; N64-Y102 PolarHBondContact N-O 3.41Å; Y102-W104 VanDerWaalsContact C-N 3.27Å; Y102-W104 HydrophobicContact CD1-CZ2 4.1Å; Y102-W104 HydrophobicContact CD2-CE3 4.47Å; Y102-W104 AromaticContact CD2-CH2 3.34Å; Y102-W104 HydrophobicContact CD2-CH2 3.34Å; Y102-W104 AromaticContact CD2-CZ2 3.54Å; Y102-W104 HydrophobicContact CD2-CZ2 3.54Å; Y102-W104 AromaticContact CD2-CZ3 3.85Å; Y102-W104 HydrophobicContact CD2-CZ3 3.85Å; Y102-W104 AromaticContact CE2-CH2 3.9Å; Y102-W104 HydrophobicContact CE2-CH2 3.9Å; Y102-W104 HydrophobicContact CE2-CZ2 4.2Å; Y102-W104 HydrophobicContact CG-CD2 4.4Å; Y102-W104 AromaticContact CG-CE2 3.79Å; Y102-W104 AromaticContact CG-CH2 3.81Å; Y102-W104 HydrophobicContact CG-CH2 3.81Å; Y102-W104 AromaticContact CG-CZ2 3.48Å; Y102-W104 HydrophobicContact CG-CZ2 3.48Å; Y102-W104 VanDerWaalsContact CG-CZ2 3.48Å; Y102-W104 HydrophobicContact CG-CZ3 4.38Å; Y102-W104 PolarHBondContact O-N 3.06Å; Y102-A158 VanDerWaalsContact CE1-O 3.26Å; Y102-A158 WeakPolarHBondContact CE1-O 3.49Å; Y102-A158 HydrophobicContact CE2-CB 3.8Å; Y102-A158 VanDerWaalsContact OH-C 3.31Å; Y102-G159 VanDerWaalsContact OH-CA 3.28Å; Y102-G159 WeakPolarHBondContact OH-CA 3.36Å; Y102-G159 PolarHBondContact OH-N 3.28Å; Y102-G159 VanDerWaalsContact OH-N 3.13Å; Y102-W227 HydrophobicContact CE2-CH2 4.13Å; Y102-W227 AromaticContact CE2-CZ2 3.62Å; Y102-W227 HydrophobicContact CE2-CZ2 3.62Å
103	P	85.8	Confident	80.5	Confident	114 Å²	114	57.1 Å²	57.1	74%	0.74	32%	0.318	S	S	*	.			trans	-82	72.7	175.3	34.1	-34.2	0	0	0	109.9
104	W	87.5	Confident	82	Confident	20 Å²	20	55 Å²	55	8%	0.076	31%	0.307	C	S	.	.			trans	-100.6	121.7	175.1	-61	-30.3	0	0	0	110.6	M59 M62 V63 Y102 T108 Q109 L112 A158 L165	M59-W104 HydrophobicContact CE-CE3 4Å; M59-W104 HydrophobicContact CE-CZ3 3.6Å; M59-W104 HydrophobicContact SD-CE3 4.29Å; M59-W104 HydrophobicContact SD-CZ3 4.47Å; M62-W104 HydrophobicContact CB-CZ3 4.03Å; M62-W104 HydrophobicContact CE-CH2 3.55Å; M62-W104 HydrophobicContact CE-CZ3 3.59Å; M62-W104 HydrophobicContact SD-CZ3 4.41Å; V63-W104 WeakPolarHBondContact CG1-O 3.19Å; V63-W104 HydrophobicContact CG2-CB 4.35Å; V63-W104 HydrophobicContact CG2-CE3 4.16Å; Y102-W104 VanDerWaalsContact C-N 3.27Å; Y102-W104 HydrophobicContact CD1-CZ2 4.1Å; Y102-W104 HydrophobicContact CD2-CE3 4.47Å; Y102-W104 AromaticContact CD2-CH2 3.34Å; Y102-W104 HydrophobicContact CD2-CH2 3.34Å; Y102-W104 AromaticContact CD2-CZ2 3.54Å; Y102-W104 HydrophobicContact CD2-CZ2 3.54Å; Y102-W104 AromaticContact CD2-CZ3 3.85Å; Y102-W104 HydrophobicContact CD2-CZ3 3.85Å; Y102-W104 AromaticContact CE2-CH2 3.9Å; Y102-W104 HydrophobicContact CE2-CH2 3.9Å; Y102-W104 HydrophobicContact CE2-CZ2 4.2Å; Y102-W104 HydrophobicContact CG-CD2 4.4Å; Y102-W104 AromaticContact CG-CE2 3.79Å; Y102-W104 AromaticContact CG-CH2 3.81Å; Y102-W104 HydrophobicContact CG-CH2 3.81Å; Y102-W104 AromaticContact CG-CZ2 3.48Å; Y102-W104 HydrophobicContact CG-CZ2 3.48Å; Y102-W104 VanDerWaalsContact CG-CZ2 3.48Å; Y102-W104 HydrophobicContact CG-CZ3 4.38Å; Y102-W104 PolarHBondContact O-N 3.06Å; W104-T108 HydrophobicContact CB-CG2 4.19Å; W104-T108 HydrophobicContact CG-CG2 4.18Å; W104-Q109 HydrophobicContact CB-CG 4.25Å; W104-Q109 PolarHBondContact O-NE2 3Å; W104-L112 HydrophobicContact CD2-CD1 4.13Å; W104-L112 HydrophobicContact CE3-CD1 3.99Å; W104-L112 HydrophobicContact CZ3-CD1 4.25Å; W104-A158 HydrophobicContact CH2-CB 4.14Å; W104-L165 HydrophobicContact CH2-CD2 3.51Å; W104-L165 HydrophobicContact CZ2-CD2 4.15Å; W104-L165 HydrophobicContact CZ3-CD2 4.01Å
105	D	85.8	Confident	83.6	Confident	77 Å²	77	48.3 Å²	48.3	41%	0.412	28%	0.275	S	S	.	.			trans	-67	161	172.6	63.8	-62.4	0	0	0	112	E107 T108 Q109	D105-E107 PolarHBondContact O-N 2.93Å; D105-E107 VanDerWaalsContact OD2-CB 3.25Å; D105-E107 WeakPolarHBondContact OD2-CB 3.35Å; D105-E107 PolarHBondContact OD2-N 2.67Å; D105-T108 PolarHBondContact O-N 2.93Å; D105-T108 VanDerWaalsContact O-N 3.15Å; D105-T108 WeakPolarHBondContact OD1-CB 3.47Å; D105-T108 PolarHBondContact OD1-OG1 3.47Å; D105-T108 PolarHBondContact OD2-N 2.89Å; D105-Q109 WeakPolarHBondContact O-CG 3.3Å; D105-Q109 PolarHBondContact O-N 3.28Å
106	S	84.3	Confident	84.8	Confident	5 Å²	5	47.5 Å²	47.5	4%	0.035	27%	0.272	C	S	.	.	H	α-helix	trans	-56.8	-33.3	-178.7	-66.9	0	0	0	0	113.5	G110 G447 T450 H453	S106-G110 PolarHBondContact O-N 2.9Å; S106-G447 WeakPolarHBondContact CB-O 3.47Å; S106-G447 VanDerWaalsContact O-CA 3.22Å; S106-G447 WeakPolarHBondContact O-CA 3.25Å; S106-T450 PolarHBondContact OG-O 3.22Å; S106-T450 VanDerWaalsContact OG-O 3.12Å; S106-H453 PolarHBondContact OG-CE1 3.01Å; S106-H453 PolarHBondContact OG-NE2 3.05Å
107	E	87	Confident	85.5	Confident	89 Å²	89	45.3 Å²	45.3	42%	0.416	26%	0.257	S	S	.	.	H	α-helix	trans	-67.7	-49.5	176.9	-162.8	-164.3	149.8	0	0	110.5	D105 Q109 G110 W111	D105-E107 PolarHBondContact O-N 2.93Å; D105-E107 VanDerWaalsContact OD2-CB 3.25Å; D105-E107 WeakPolarHBondContact OD2-CB 3.35Å; D105-E107 PolarHBondContact OD2-N 2.67Å; E107-Q109 VanDerWaalsContact C-N 3.29Å; E107-Q109 PolarHBondContact O-N 3.22Å; E107-G110 PolarHBondContact O-N 2.92Å; E107-G110 VanDerWaalsContact O-N 3.09Å; E107-W111 VanDerWaalsContact O-CD1 3.22Å; E107-W111 PolarHBondContact O-N 3.42Å; E107-W111 PolarHBondContact OE1-NE1 3.29Å; E107-W111 VanDerWaalsContact OE1-NE1 3.11Å
108	T	89.2	Confident	86.7	Confident	34 Å²	34	40.9 Å²	40.9	21%	0.209	23%	0.23	C	C	.	.	H	α-helix	trans	-56.8	-42.2	175.5	-64.9	0	0	0	0	111.8	W104 D105 G110 W111 L112	W104-T108 HydrophobicContact CB-CG2 4.19Å; W104-T108 HydrophobicContact CG-CG2 4.18Å; D105-T108 PolarHBondContact O-N 2.93Å; D105-T108 VanDerWaalsContact O-N 3.15Å; D105-T108 WeakPolarHBondContact OD1-CB 3.47Å; D105-T108 PolarHBondContact OD1-OG1 3.47Å; D105-T108 PolarHBondContact OD2-N 2.89Å; T108-G110 VanDerWaalsContact C-N 3.35Å; T108-G110 PolarHBondContact O-N 3.13Å; T108-W111 PolarHBondContact O-N 3.18Å; T108-L112 HydrophobicContact CG2-CD1 3.95Å; T108-L112 HydrophobicContact CG2-CG 4.28Å; T108-L112 WeakPolarHBondContact O-CB 3.34Å; T108-L112 VanDerWaalsContact O-CG 3.27Å; T108-L112 WeakPolarHBondContact O-CG 3.44Å; T108-L112 PolarHBondContact O-N 3.05Å
109	Q	88.9	Confident	87.8	Confident	15 Å²	15	37.3 Å²	37.3	7%	0.07	19%	0.193	C	C	.	.	H	α-helix	trans	-60.4	-44.1	175.7	-65.9	174.5	45.3	0	0	111.7	M59 V63 W104 D105 E107 W111 L112 L113	M59-Q109 HydrophobicContact CG-CB 4.35Å; M59-Q109 HydrophobicContact CG-CG 4.08Å; M59-Q109 HydrophobicContact SD-CB 4.17Å; M59-Q109 HydrophobicContact SD-CG 4Å; V63-Q109 HydrophobicContact CG2-CG 4Å; W104-Q109 HydrophobicContact CB-CG 4.25Å; W104-Q109 PolarHBondContact O-NE2 3Å; D105-Q109 WeakPolarHBondContact O-CG 3.3Å; D105-Q109 PolarHBondContact O-N 3.28Å; E107-Q109 VanDerWaalsContact C-N 3.29Å; E107-Q109 PolarHBondContact O-N 3.22Å; Q109-W111 PolarHBondContact O-N 3Å; Q109-L112 PolarHBondContact O-N 3.15Å; Q109-L113 WeakPolarHBondContact O-CB 3.34Å; Q109-L113 WeakPolarHBondContact O-CG 3.44Å; Q109-L113 PolarHBondContact O-N 3.33Å
110	G	88.3	Confident	88.3	Confident	3 Å²	3	36.2 Å²	36.2	3%	0.031	19%	0.186	C	C	.	.	H	α-helix	trans	-59.2	-44.3	175.2	0	0	0	0	0	112.7	S106 E107 T108 G114 P443	S106-G110 PolarHBondContact O-N 2.9Å; E107-G110 PolarHBondContact O-N 2.92Å; E107-G110 VanDerWaalsContact O-N 3.09Å; T108-G110 VanDerWaalsContact C-N 3.35Å; T108-G110 PolarHBondContact O-N 3.13Å; G110-G114 PolarHBondContact O-N 3.06Å; G110-P443 WeakPolarHBondContact CA-O 3.21Å; G110-P443 WeakPolarHBondContact O-CB 3.44Å
111	W	92	Very high	88.7	Confident	97 Å²	97	36.1 Å²	36.1	37%	0.367	18%	0.181	S	C	.	.	H	α-helix	trans	-63.6	-41.1	174.7	-78.8	106.3	0	0	0	112.9	E107 T108 Q109 G114 A115 F118 F166 I444	E107-W111 VanDerWaalsContact O-CD1 3.22Å; E107-W111 PolarHBondContact O-N 3.42Å; E107-W111 PolarHBondContact OE1-NE1 3.29Å; E107-W111 VanDerWaalsContact OE1-NE1 3.11Å; T108-W111 PolarHBondContact O-N 3.18Å; Q109-W111 PolarHBondContact O-N 3Å; W111-G114 PolarHBondContact O-N 3.41Å; W111-A115 WeakPolarHBondContact O-CB 3.38Å; W111-A115 PolarHBondContact O-N 3.31Å; W111-F118 HydrophobicContact CE3-CE2 4.36Å; W111-F118 HydrophobicContact CZ3-CE2 4.06Å; W111-F118 HydrophobicContact CZ3-CZ 4.06Å; W111-F166 HydrophobicContact CE3-CE2 4.2Å; W111-I444 HydrophobicContact CD2-CD1 4.15Å; W111-I444 HydrophobicContact CD2-CG1 4.2Å; W111-I444 HydrophobicContact CE3-CD1 3.72Å; W111-I444 HydrophobicContact CE3-CG1 4.21Å; W111-I444 HydrophobicContact CH2-CD1 4.06Å; W111-I444 HydrophobicContact CZ2-CD1 4.45Å; W111-I444 HydrophobicContact CZ2-CG2 4.23Å; W111-I444 HydrophobicContact CZ3-CD1 3.68Å
112	L	92.5	Very high	88.8	Confident	3 Å²	3	36.2 Å²	36.2	2%	0.016	19%	0.191	C	C	.	.	H	α-helix	trans	-66.6	-41.8	178.6	-72	172.8	0	0	0	112.4	M59 W104 T108 Q109 A115 S162 L165 F166	M59-L112 HydrophobicContact SD-CD1 4.42Å; W104-L112 HydrophobicContact CD2-CD1 4.13Å; W104-L112 HydrophobicContact CE3-CD1 3.99Å; W104-L112 HydrophobicContact CZ3-CD1 4.25Å; T108-L112 HydrophobicContact CG2-CD1 3.95Å; T108-L112 HydrophobicContact CG2-CG 4.28Å; T108-L112 WeakPolarHBondContact O-CB 3.34Å; T108-L112 VanDerWaalsContact O-CG 3.27Å; T108-L112 WeakPolarHBondContact O-CG 3.44Å; T108-L112 PolarHBondContact O-N 3.05Å; Q109-L112 PolarHBondContact O-N 3.15Å; L112-A115 WeakPolarHBondContact O-CB 3.18Å; L112-A115 PolarHBondContact O-N 3.28Å; L112-S162 WeakPolarHBondContact CD2-O 3.36Å; L112-L165 HydrophobicContact CD1-CD2 3.98Å; L112-L165 HydrophobicContact CD2-CB 4.01Å; L112-L165 HydrophobicContact CD2-CD2 4.01Å; L112-L165 HydrophobicContact CD2-CG 3.89Å; L112-F166 HydrophobicContact CD2-CB 3.98Å
113	L	88.4	Confident	88.8	Confident	18 Å²	18	34.9 Å²	34.9	9%	0.094	19%	0.186	C	C	.	.	H	α-helix	trans	-67.5	-37.8	175.5	-70	168.3	0	0	0	111.6	L55 Q109 P443	L55-L113 HydrophobicContact CD2-CD2 4.08Å; L55-L113 HydrophobicContact CG-CD2 4.07Å; Q109-L113 WeakPolarHBondContact O-CB 3.34Å; Q109-L113 WeakPolarHBondContact O-CG 3.44Å; Q109-L113 PolarHBondContact O-N 3.33Å; L113-P443 HydrophobicContact CB-CB 3.93Å
114	G	88.6	Confident	88.8	Confident	0 Å²	0	29.8 Å²	29.8	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-74.6	-24.4	176.1	0	0	0	0	0	114.7	G110 W111 F116 F117	G110-G114 PolarHBondContact O-N 3.06Å; W111-G114 PolarHBondContact O-N 3.41Å; G114-F116 VanDerWaalsContact C-N 3.25Å; G114-F116 PolarHBondContact O-N 3.4Å; G114-F117 PolarHBondContact O-N 3.36Å
115	A	92.8	Very high	88.5	Confident	0 Å²	0	34 Å²	34	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-52.8	-39.9	-175.5	0	0	0	0	0	113.5	W111 L112 F117 F118 F166 R169 A170	W111-A115 WeakPolarHBondContact O-CB 3.38Å; W111-A115 PolarHBondContact O-N 3.31Å; L112-A115 WeakPolarHBondContact O-CB 3.18Å; L112-A115 PolarHBondContact O-N 3.28Å; A115-F117 VanDerWaalsContact C-N 3.29Å; A115-F117 PolarHBondContact O-N 3.06Å; A115-F118 PolarHBondContact O-N 3.29Å; A115-F166 HydrophobicContact CB-CD2 3.48Å; A115-F166 VanDerWaalsContact CB-CD2 3.48Å; A115-F166 HydrophobicContact CB-CE2 3.55Å; A115-F166 HydrophobicContact CB-CG 4.1Å; A115-F166 HydrophobicContact CB-CZ 4.23Å; A115-R169 HydrophobicContact CB-CB 3.62Å; A115-A170 WeakPolarHBondContact O-CA 3.18Å
116	F	92.1	Very high	88.4	Confident	9 Å²	9	33.4 Å²	33.4	4%	0.039	18%	0.176	C	C	.	.	H	α-helix	trans	-55.5	-43.9	176.7	175	-87.3	0	0	0	112.1	R52 G114 F118 G119 Y120 R169 E172 G173 E176	R52-F116 HydrophobicContact CB-CZ 4.47Å; R52-F116 HydrophobicContact CG-CD1 4.19Å; R52-F116 HydrophobicContact CG-CE1 3.92Å; R52-F116 HydrophobicContact CG-CE2 4.44Å; R52-F116 HydrophobicContact CG-CZ 4.06Å; R52-F116 VanDerWaalsContact NE-CE1 3.33Å; G114-F116 VanDerWaalsContact C-N 3.25Å; G114-F116 PolarHBondContact O-N 3.4Å; F116-F118 VanDerWaalsContact C-N 3.3Å; F116-F118 PolarHBondContact O-N 3.26Å; F116-G119 PolarHBondContact O-N 3.46Å; F116-Y120 AromaticContact CE1-CD2 3.93Å; F116-Y120 HydrophobicContact CE1-CD2 3.93Å; F116-Y120 HydrophobicContact CE1-CG 4.2Å; F116-Y120 HydrophobicContact CZ-CD2 4.01Å; F116-Y120 WeakPolarHBondContact O-CB 3.09Å; F116-Y120 PolarHBondContact O-N 3.38Å; F116-Y120 VanDerWaalsContact O-N 3.14Å; F116-R169 WeakPolarHBondContact CA-O 3.28Å; F116-E172 HydrophobicContact CD2-CB 4.27Å; F116-G173 VanDerWaalsContact CE2-CA 3.48Å; F116-G173 VanDerWaalsContact O-CA 3.31Å; F116-G173 WeakPolarHBondContact O-CA 3.32Å; F116-E176 HydrophobicContact CE2-CB 4.04Å; F116-E176 VanDerWaalsContact CE2-OE2 3.22Å; F116-E176 WeakPolarHBondContact CE2-OE2 3.43Å; F116-E176 HydrophobicContact CZ-CB 3.84Å; F116-E176 HydrophobicContact CZ-CG 4.09Å; F116-E176 WeakPolarHBondContact CZ-OE1 3.14Å; F116-E176 WeakPolarHBondContact CZ-OE2 3.47Å
117	F	89.9	Confident	88.3	Confident	4 Å²	4	33.3 Å²	33.3	2%	0.018	18%	0.175	C	C	.	.	H	α-helix	trans	-71.9	-23.8	-175.2	-69.4	-82.3	0	0	0	113.2	G114 A115 Y120 L121 Y308 T312 G439 V440	G114-F117 PolarHBondContact O-N 3.36Å; A115-F117 VanDerWaalsContact C-N 3.29Å; A115-F117 PolarHBondContact O-N 3.06Å; F117-Y120 PolarHBondContact O-N 3.28Å; F117-L121 WeakPolarHBondContact O-CB 3.36Å; F117-L121 PolarHBondContact O-N 3.42Å; F117-Y308 HydrophobicContact CE1-CD1 4.09Å; F117-Y308 AromaticContact CE1-CE1 3.78Å; F117-Y308 HydrophobicContact CE1-CE1 3.78Å; F117-Y308 HydrophobicContact CE1-CE2 4.3Å; F117-Y308 AromaticContact CE1-CZ 3.89Å; F117-Y308 AromaticContact CZ-CD1 3.71Å; F117-Y308 HydrophobicContact CZ-CD1 3.71Å; F117-Y308 AromaticContact CZ-CE1 3.82Å; F117-Y308 HydrophobicContact CZ-CE1 3.82Å; F117-Y308 HydrophobicContact CZ-CG 4.2Å; F117-T312 HydrophobicContact CE2-CG2 4.4Å; F117-G439 WeakPolarHBondContact CD2-O 3.49Å; F117-G439 WeakPolarHBondContact CE2-O 3.29Å; F117-G439 VanDerWaalsContact CG-C 3.45Å; F117-V440 HydrophobicContact CB-CB 4.29Å; F117-V440 HydrophobicContact CB-CG2 3.39Å
118	F	90.8	Very high	88	Confident	83 Å²	83	30.2 Å²	30.2	36%	0.364	17%	0.167	S	C	.	.	H	α-helix	trans	-61.2	-51	173	-81.1	-76.4	0	0	0	111.5	W111 A115 F116 Y120 C122 F166 V440 I444	W111-F118 HydrophobicContact CE3-CE2 4.36Å; W111-F118 HydrophobicContact CZ3-CE2 4.06Å; W111-F118 HydrophobicContact CZ3-CZ 4.06Å; A115-F118 PolarHBondContact O-N 3.29Å; F116-F118 VanDerWaalsContact C-N 3.3Å; F116-F118 PolarHBondContact O-N 3.26Å; F118-Y120 VanDerWaalsContact C-N 3.33Å; F118-C122 PolarHBondContact O-N 2.75Å; F118-C122 PolarHBondContact O-SG 3.07Å; F118-C122 VanDerWaalsContact O-SG 3.4Å; F118-F166 HydrophobicContact CD2-CZ 4.35Å; F118-F166 HydrophobicContact CE2-CZ 4.5Å; F118-V440 HydrophobicContact CD1-CG1 4.16Å; F118-V440 HydrophobicContact CD2-CG1 3.84Å; F118-V440 HydrophobicContact CE1-CG1 3.72Å; F118-V440 HydrophobicContact CE2-CG1 3.38Å; F118-V440 HydrophobicContact CG-CG1 4.22Å; F118-V440 HydrophobicContact CZ-CG1 3.31Å; F118-I444 HydrophobicContact CE2-CD1 4.37Å
119	G	89.4	Confident	87.5	Confident	8 Å²	8	34.9 Å²	34.9	8%	0.082	18%	0.182	C	C	.	.	H	α-helix	trans	-63.2	-42.8	176.9	0	0	0	0	0	112	F116 L121 C122 T123 A170	F116-G119 PolarHBondContact O-N 3.46Å; G119-L121 VanDerWaalsContact C-N 3.34Å; G119-L121 PolarHBondContact O-N 3.39Å; G119-C122 PolarHBondContact O-N 3.19Å; G119-T123 PolarHBondContact O-N 3.48Å; G119-T123 PolarHBondContact O-OG1 3.24Å; G119-A170 WeakPolarHBondContact CA-O 3.36Å
120	Y	89.7	Confident	87.3	Confident	3 Å²	3	37.1 Å²	37.1	1%	0.012	19%	0.194	C	C	.	.	H	α-helix	trans	-58.7	-43.4	-178.9	-168.3	-96.7	0	0	0	112.6	F116 F117 F118 T123 Q124 G173 E176 G177 F180 T436	F116-Y120 AromaticContact CE1-CD2 3.93Å; F116-Y120 HydrophobicContact CE1-CD2 3.93Å; F116-Y120 HydrophobicContact CE1-CG 4.2Å; F116-Y120 HydrophobicContact CZ-CD2 4.01Å; F116-Y120 WeakPolarHBondContact O-CB 3.09Å; F116-Y120 PolarHBondContact O-N 3.38Å; F116-Y120 VanDerWaalsContact O-N 3.14Å; F117-Y120 PolarHBondContact O-N 3.28Å; F118-Y120 VanDerWaalsContact C-N 3.33Å; Y120-T123 PolarHBondContact O-N 3.01Å; Y120-T123 PolarHBondContact O-OG1 3.37Å; Y120-Q124 HydrophobicContact CD1-CG 4.28Å; Y120-Q124 HydrophobicContact CE1-CG 3.97Å; Y120-Q124 PolarHBondContact O-N 3.42Å; Y120-G173 VanDerWaalsContact CA-O 3.24Å; Y120-G173 WeakPolarHBondContact CA-O 3.45Å; Y120-G173 PolarHBondContact N-O 2.78Å; Y120-E176 HydrophobicContact CD2-CB 4.32Å; Y120-G177 VanDerWaalsContact CE2-CA 3.42Å; Y120-F180 VanDerWaalsContact OH-CD2 3.23Å; Y120-F180 WeakPolarHBondContact OH-CD2 3.43Å; Y120-T436 HydrophobicContact CD1-CG2 3.93Å; Y120-T436 HydrophobicContact CE1-CG2 3.59Å
121	L	88.3	Confident	87	Confident	59 Å²	59	37 Å²	37	31%	0.309	19%	0.193	S	C	.	.	H	α-helix	trans	-63.6	-41.7	179.6	-169.4	110.5	0	0	0	112.1	F117 G119 T123 T433 I437	F117-L121 WeakPolarHBondContact O-CB 3.36Å; F117-L121 PolarHBondContact O-N 3.42Å; G119-L121 VanDerWaalsContact C-N 3.34Å; G119-L121 PolarHBondContact O-N 3.39Å; L121-T123 PolarHBondContact O-N 3.1Å; L121-T433 HydrophobicContact CD1-CG2 4.44Å; L121-T433 HydrophobicContact CG-CG2 4.47Å; L121-I437 HydrophobicContact CD1-CG1 3.55Å
122	C	86.8	Confident	86.1	Confident	85 Å²	85	34.1 Å²	34.1	57%	0.574	19%	0.193	S	C	*	.	H	α-helix	trans	-63.9	-28.7	-177.8	-68.4	0	0	0	0	113.2	F118 G119 P126	F118-C122 PolarHBondContact O-N 2.75Å; F118-C122 PolarHBondContact O-SG 3.07Å; F118-C122 VanDerWaalsContact O-SG 3.4Å; G119-C122 PolarHBondContact O-N 3.19Å; C122-P126 VanDerWaalsContact O-CD 3.3Å; C122-P126 WeakPolarHBondContact O-CD 3.36Å; C122-P126 WeakPolarHBondContact O-CG 3.34Å
123	T	87.7	Confident	85.3	Confident	7 Å²	7	39.1 Å²	39.1	4%	0.043	22%	0.216	C	C	.	.	H	α-helix	trans	-102.3	-14.4	-171	49.1	0	0	0	0	115.3	G119 Y120 L121 G127 F174 G177	G119-T123 PolarHBondContact O-N 3.48Å; G119-T123 PolarHBondContact O-OG1 3.24Å; Y120-T123 PolarHBondContact O-N 3.01Å; Y120-T123 PolarHBondContact O-OG1 3.37Å; L121-T123 PolarHBondContact O-N 3.1Å; T123-G127 WeakPolarHBondContact O-CA 3.49Å; T123-G127 PolarHBondContact O-N 3.37Å; T123-F174 HydrophobicContact CG2-CB 4.19Å; T123-F174 HydrophobicContact CG2-CD1 3.92Å; T123-F174 HydrophobicContact CG2-CD2 3.12Å; T123-F174 HydrophobicContact CG2-CE1 4.01Å; T123-F174 HydrophobicContact CG2-CE2 3.22Å; T123-F174 HydrophobicContact CG2-CG 3.48Å; T123-F174 VanDerWaalsContact CG2-CG 3.48Å; T123-F174 HydrophobicContact CG2-CZ 3.67Å; T123-F174 WeakPolarHBondContact CG2-O 3.44Å; T123-F174 PolarHBondContact OG1-O 3.09Å; T123-G177 VanDerWaalsContact OG1-CA 3.29Å; T123-G177 WeakPolarHBondContact OG1-CA 3.48Å
124	Q	84.3	Confident	84.9	Confident	7 Å²	7	46.3 Å²	46.3	3%	0.033	24%	0.244	C	C	.	.	H	α-helix	trans	-60.2	-52.5	-177.4	-85.7	-162.5	68.5	0	0	113.4	Y120 G128 G177 P181 N432 T436	Y120-Q124 HydrophobicContact CD1-CG 4.28Å; Y120-Q124 HydrophobicContact CE1-CG 3.97Å; Y120-Q124 PolarHBondContact O-N 3.42Å; Q124-G128 PolarHBondContact O-N 2.83Å; Q124-G177 WeakPolarHBondContact CG-O 3.08Å; Q124-P181 WeakPolarHBondContact O-CG 3.35Å; Q124-N432 PolarHBondContact OE1-ND2 2.89Å; Q124-T436 PolarHBondContact NE2-OG1 3.02Å; Q124-T436 VanDerWaalsContact NE2-OG1 3.14Å
125	I	82	Confident	84.5	Confident	107 Å²	107	46.4 Å²	46.4	55%	0.549	24%	0.244	S	C	.	.	H	α-helix	trans	-69.1	-53	-178.3	-59.3	173.7	0	0	0	111.1	G127 G128 Y129 T433	I125-G127 VanDerWaalsContact C-N 3.31Å; I125-G127 PolarHBondContact O-N 3.33Å; I125-G128 PolarHBondContact O-N 3.05Å; I125-Y129 PolarHBondContact O-N 3Å; I125-T433 HydrophobicContact CD1-CG2 3.94Å; I125-T433 HydrophobicContact CG1-CG2 4.09Å
126	P	84.4	Confident	84.1	Confident	66 Å²	66	46.5 Å²	46.5	43%	0.429	25%	0.245	S	C	.	.	H	α-helix	trans	-63.8	-37.9	179.2	-21.1	34.7	0	0	0	112.4	C122 G128 Y129 L130	C122-P126 VanDerWaalsContact O-CD 3.3Å; C122-P126 WeakPolarHBondContact O-CD 3.36Å; C122-P126 WeakPolarHBondContact O-CG 3.34Å; P126-G128 PolarHBondContact O-N 2.99Å; P126-Y129 PolarHBondContact O-N 3.14Å; P126-L130 WeakPolarHBondContact O-CB 3.4Å; P126-L130 VanDerWaalsContact O-CG 3.26Å; P126-L130 WeakPolarHBondContact O-CG 3.24Å; P126-L130 PolarHBondContact O-N 2.99Å
127	G	82.4	Confident	84	Confident	3 Å²	3	48.3 Å²	48.3	3%	0.031	25%	0.253	C	S	.	.	H	α-helix	trans	-62.4	-40.9	178	0	0	0	0	0	112.8	T123 I125 A131	T123-G127 WeakPolarHBondContact O-CA 3.49Å; T123-G127 PolarHBondContact O-N 3.37Å; I125-G127 VanDerWaalsContact C-N 3.31Å; I125-G127 PolarHBondContact O-N 3.33Å; G127-A131 WeakPolarHBondContact O-CB 3.44Å; G127-A131 PolarHBondContact O-N 3Å
128	G	79.3	Confident	84	Confident	24 Å²	24	52.7 Å²	52.7	25%	0.247	28%	0.276	C	S	.	.	H	α-helix	trans	-63.1	-45.4	174	0	0	0	0	0	113.1	Q124 I125 P126 G132	Q124-G128 PolarHBondContact O-N 2.83Å; I125-G128 PolarHBondContact O-N 3.05Å; P126-G128 PolarHBondContact O-N 2.99Å; G128-G132 PolarHBondContact O-N 3.35Å; G128-G132 VanDerWaalsContact O-N 3.09Å
129	Y	79.8	Confident	83.9	Confident	131 Å²	131	51 Å²	51	51%	0.514	27%	0.268	S	S	.	.	H	α-helix	trans	-61.5	-50.2	177	179.4	-100.1	0	0	0	111.7	I125 P126 G132 H133 W280	I125-Y129 PolarHBondContact O-N 3Å; P126-Y129 PolarHBondContact O-N 3.14Å; Y129-G132 PolarHBondContact O-N 2.94Å; Y129-H133 AromaticContact CE1-CD2 3.81Å; Y129-H133 AromaticContact CE2-CD2 3.69Å; Y129-H133 AromaticContact CE2-NE2 3.46Å; Y129-H133 WeakPolarHBondContact CE2-NE2 3.4Å; Y129-H133 AromaticContact CZ-CD2 3.52Å; Y129-H133 AromaticContact CZ-NE2 3.43Å; Y129-H133 PolarHBondContact O-CD2 3.17Å; Y129-H133 PolarHBondContact O-N 3.06Å; Y129-H133 PolarHBondContact OH-NE2 3.34Å; Y129-W280 HydrophobicContact CE2-CZ2 4.37Å
130	L	83.4	Confident	84	Confident	62 Å²	62	50.8 Å²	50.8	33%	0.325	27%	0.266	S	S	.	.	H	α-helix	trans	-67.5	-38.1	-178.5	-67.3	169.4	0	0	0	112.4	P126 G132 H133 Y134 F139	P126-L130 WeakPolarHBondContact O-CB 3.4Å; P126-L130 VanDerWaalsContact O-CG 3.26Å; P126-L130 WeakPolarHBondContact O-CG 3.24Å; P126-L130 PolarHBondContact O-N 2.99Å; L130-G132 VanDerWaalsContact C-N 3.3Å; L130-G132 PolarHBondContact O-N 3.35Å; L130-H133 PolarHBondContact O-N 3.26Å; L130-Y134 HydrophobicContact CD2-CD2 4.09Å; L130-Y134 HydrophobicContact CD2-CE2 3.77Å; L130-Y134 PolarHBondContact O-N 3.24Å; L130-F139 HydrophobicContact CB-CE1 3.85Å; L130-F139 HydrophobicContact CB-CE2 3.82Å; L130-F139 HydrophobicContact CB-CZ 3.37Å; L130-F139 HydrophobicContact CD1-CE1 4.21Å; L130-F139 HydrophobicContact CD1-CZ 4.18Å; L130-F139 HydrophobicContact CG-CZ 4.32Å; L130-F139 WeakPolarHBondContact O-CE2 3.29Å
131	A	81.7	Confident	84.1	Confident	1 Å²	1	50.7 Å²	50.7	1%	0.008	27%	0.265	C	S	.	.	H	α-helix	trans	-65.2	-33.5	176	0	0	0	0	0	112.5	G127 G135 G136 F139 A182 A185	G127-A131 WeakPolarHBondContact O-CB 3.44Å; G127-A131 PolarHBondContact O-N 3Å; A131-G135 CarbonylContact O-C 3.51Å; A131-G135 VanDerWaalsContact O-C 3.27Å; A131-G135 WeakPolarHBondContact O-CA 3.35Å; A131-G135 PolarHBondContact O-N 2.79Å; A131-G136 PolarHBondContact O-N 2.91Å; A131-F139 HydrophobicContact CB-CB 4.1Å; A131-F139 HydrophobicContact CB-CD2 4.02Å; A131-F139 HydrophobicContact CB-CG 4.14Å; A131-A182 HydrophobicContact CB-CB 3.83Å; A131-A185 HydrophobicContact CB-CB 4.26Å
132	G	74.3	Confident	84.3	Confident	36 Å²	36	52.7 Å²	52.7	37%	0.371	27%	0.274	S	S	.	.	H	α-helix	trans	-63.1	-40.4	172.3	0	0	0	0	0	112.9	G128 Y129 L130 R189	G128-G132 PolarHBondContact O-N 3.35Å; G128-G132 VanDerWaalsContact O-N 3.09Å; Y129-G132 PolarHBondContact O-N 2.94Å; L130-G132 VanDerWaalsContact C-N 3.3Å; L130-G132 PolarHBondContact O-N 3.35Å; G132-R189 PolarHBondContact O-NH2 3.41Å
133	H	76.5	Confident	84.6	Confident	108 Å²	108	49 Å²	49	50%	0.5	25%	0.251	S	S	.	.	H	α-helix	trans	-82.4	-53	-176.6	-83.3	-73.9	0	0	0	114	Y129 L130	Y129-H133 AromaticContact CE1-CD2 3.81Å; Y129-H133 AromaticContact CE2-CD2 3.69Å; Y129-H133 AromaticContact CE2-NE2 3.46Å; Y129-H133 WeakPolarHBondContact CE2-NE2 3.4Å; Y129-H133 AromaticContact CZ-CD2 3.52Å; Y129-H133 AromaticContact CZ-NE2 3.43Å; Y129-H133 PolarHBondContact O-CD2 3.17Å; Y129-H133 PolarHBondContact O-N 3.06Å; Y129-H133 PolarHBondContact OH-NE2 3.34Å; L130-H133 PolarHBondContact O-N 3.26Å
134	Y	80	Confident	84.9	Confident	170 Å²	170	48.7 Å²	48.7	67%	0.667	25%	0.249	S	C	*	.	H	α-helix	trans	-95.9	0.8	-172.6	-59.6	-85.1	0	0	0	113.9	L130	L130-Y134 HydrophobicContact CD2-CD2 4.09Å; L130-Y134 HydrophobicContact CD2-CE2 3.77Å; L130-Y134 PolarHBondContact O-N 3.24Å
135	G	78.9	Confident	85.5	Confident	1 Å²	1	51.7 Å²	51.7	1%	0.01	26%	0.262	C	S	.	.			trans	100	133.9	177.1	0	0	0	0	0	113.3	A131 K137 D251	A131-G135 CarbonylContact O-C 3.51Å; A131-G135 VanDerWaalsContact O-C 3.27Å; A131-G135 WeakPolarHBondContact O-CA 3.35Å; A131-G135 PolarHBondContact O-N 2.79Å; G135-K137 PolarHBondContact O-N 2.94Å; G135-D251 VanDerWaalsContact C-OD1 3.27Å; G135-D251 WeakPolarHBondContact CA-OD1 3.49Å
136	G	83.6	Confident	86.1	Confident	3 Å²	3	47.9 Å²	47.9	3%	0.031	25%	0.249	C	C	.	.	H	α-helix	trans	-72.5	-22.8	-175.2	0	0	0	0	0	114.3	A131 I138 L140 D251	A131-G136 PolarHBondContact O-N 2.91Å; G136-I138 PolarHBondContact O-N 2.91Å; G136-L140 WeakPolarHBondContact O-CB 3.19Å; G136-L140 PolarHBondContact O-N 2.9Å; G136-D251 PolarHBondContact N-OD1 3.32Å; G136-D251 VanDerWaalsContact N-OD1 3.15Å
137	K	90.1	Very high	86.6	Confident	46 Å²	46	44.9 Å²	44.9	20%	0.2	23%	0.229	C	C	.	.	H	α-helix	trans	-60.3	-46.1	179.4	179.6	-171	170.5	175.8	0	111.6	G135 G141 W245 C246 V249 D251	G135-K137 PolarHBondContact O-N 2.94Å; K137-G141 PolarHBondContact O-N 3.42Å; K137-W245 HydrophobicContact CG-CZ2 4.38Å; K137-W245 PolarHBondContact O-NE1 3.4Å; K137-C246 PolarHBondContact NZ-O 2.95Å; K137-V249 HydrophobicContact CD-CG1 4.45Å; K137-V249 WeakPolarHBondContact CD-O 3.48Å; K137-V249 WeakPolarHBondContact CE-O 3.41Å; K137-V249 HydrophobicContact CG-CG1 4.19Å; K137-V249 PolarHBondContact NZ-O 3.45Å; K137-D251 WeakPolarHBondContact CA-OD1 3.36Å; K137-D251 HydrophobicContact CB-CB 4.48Å; K137-D251 WeakPolarHBondContact CB-OD1 3.07Å; K137-D251 WeakPolarHBondContact CB-OD2 3.34Å; K137-D251 PolarHBondContact N-OD1 3.48Å
138	I	90.1	Very high	87.2	Confident	97 Å²	97	44.7 Å²	44.7	50%	0.497	23%	0.228	S	C	.	.	H	α-helix	trans	-67.9	-49.7	-176.2	-61.8	176.8	0	0	0	109.4	G136 G141 M142	G136-I138 PolarHBondContact O-N 2.91Å; I138-G141 PolarHBondContact O-N 3.19Å; I138-M142 HydrophobicContact CG2-CG 4.04Å; I138-M142 WeakPolarHBondContact O-CB 3.49Å; I138-M142 VanDerWaalsContact O-CG 3.29Å; I138-M142 WeakPolarHBondContact O-CG 3.38Å; I138-M142 PolarHBondContact O-N 3.28Å
139	F	90.1	Very high	88.1	Confident	47 Å²	47	46.1 Å²	46.1	21%	0.206	23%	0.231	C	C	.	.	H	α-helix	trans	-63.4	-45.9	-179.4	-80.3	-81.2	0	0	0	112.7	L130 A131 G143 V178 A182	L130-F139 HydrophobicContact CB-CE1 3.85Å; L130-F139 HydrophobicContact CB-CE2 3.82Å; L130-F139 HydrophobicContact CB-CZ 3.37Å; L130-F139 HydrophobicContact CD1-CE1 4.21Å; L130-F139 HydrophobicContact CD1-CZ 4.18Å; L130-F139 HydrophobicContact CG-CZ 4.32Å; L130-F139 WeakPolarHBondContact O-CE2 3.29Å; A131-F139 HydrophobicContact CB-CB 4.1Å; A131-F139 HydrophobicContact CB-CD2 4.02Å; A131-F139 HydrophobicContact CB-CG 4.14Å; F139-G143 WeakPolarHBondContact O-CA 3.38Å; F139-G143 PolarHBondContact O-N 3.49Å; F139-V178 HydrophobicContact CB-CG2 4.34Å; F139-V178 HydrophobicContact CD1-CB 4.46Å; F139-V178 HydrophobicContact CD1-CG1 4.48Å; F139-V178 WeakPolarHBondContact O-CG2 3.3Å; F139-A182 HydrophobicContact CB-CB 3.99Å
140	L	91.1	Very high	88.8	Confident	4 Å²	4	41.7 Å²	41.7	2%	0.021	22%	0.216	C	C	.	.	H	α-helix	trans	-66.4	-46.4	179.1	-167	146.2	0	0	0	110.8	G136 V144 A182 M183 W241 W245	G136-L140 WeakPolarHBondContact O-CB 3.19Å; G136-L140 PolarHBondContact O-N 2.9Å; L140-V144 VanDerWaalsContact O-CG2 3.28Å; L140-V144 WeakPolarHBondContact O-CG2 3.46Å; L140-V144 PolarHBondContact O-N 3.42Å; L140-V144 VanDerWaalsContact O-N 3.11Å; L140-A182 HydrophobicContact CB-CB 3.84Å; L140-A182 HydrophobicContact CD1-CB 4.46Å; L140-M183 HydrophobicContact CD1-CB 3.83Å; L140-W241 HydrophobicContact CD2-CH2 3.46Å; L140-W241 VanDerWaalsContact CD2-CH2 3.46Å; L140-W241 HydrophobicContact CD2-CZ2 4.18Å; L140-W241 HydrophobicContact CD2-CZ3 4.39Å; L140-W245 HydrophobicContact CB-CZ2 4.21Å; L140-W245 HydrophobicContact CD2-CD2 4.34Å; L140-W245 HydrophobicContact CD2-CE3 4.43Å; L140-W245 HydrophobicContact CD2-CH2 3.73Å; L140-W245 HydrophobicContact CD2-CZ2 3.58Å; L140-W245 HydrophobicContact CD2-CZ3 4.15Å; L140-W245 HydrophobicContact CG-CZ2 4.39Å
141	G	92.5	Very high	89.4	Confident	1 Å²	1	38.7 Å²	38.7	1%	0.01	20%	0.201	C	C	.	.	H	α-helix	trans	-65	-52.6	-179.5	0	0	0	0	0	113.1	K137 I138 G143 V144 F145 F242 W245	K137-G141 PolarHBondContact O-N 3.42Å; I138-G141 PolarHBondContact O-N 3.19Å; G141-G143 VanDerWaalsContact C-N 3.31Å; G141-G143 PolarHBondContact O-N 3.36Å; G141-V144 PolarHBondContact O-N 3.3Å; G141-F145 WeakPolarHBondContact O-CB 3.49Å; G141-F145 PolarHBondContact O-N 3.13Å; G141-F242 WeakPolarHBondContact O-CD2 3.38Å; G141-F242 VanDerWaalsContact O-CE2 3.32Å; G141-F242 WeakPolarHBondContact O-CE2 3.4Å; G141-W245 VanDerWaalsContact CA-CD1 3.49Å
142	M	92.4	Very high	90.1	Very high	101 Å²	101	41 Å²	41	50%	0.498	22%	0.215	S	C	.	.	H	α-helix	trans	-67.2	-32.9	-179.4	-67.6	-60.5	-61.3	0	0	112.1	I138 F145 G146 F242	I138-M142 HydrophobicContact CG2-CG 4.04Å; I138-M142 WeakPolarHBondContact O-CB 3.49Å; I138-M142 VanDerWaalsContact O-CG 3.29Å; I138-M142 WeakPolarHBondContact O-CG 3.38Å; I138-M142 PolarHBondContact O-N 3.28Å; M142-F145 HydrophobicContact CE-CD1 4.47Å; M142-G146 PolarHBondContact O-N 3.23Å; M142-F242 HydrophobicContact SD-CE2 4.19Å; M142-F242 HydrophobicContact SD-CZ 3.76Å
143	G	92.8	Very high	91.1	Very high	7 Å²	7	43 Å²	43	7%	0.072	22%	0.216	C	C	.	.	H	α-helix	trans	-60.5	-54.2	173.1	0	0	0	0	0	111.5	F139 G141 F145 G146 T147 G175	F139-G143 WeakPolarHBondContact O-CA 3.38Å; F139-G143 PolarHBondContact O-N 3.49Å; G141-G143 VanDerWaalsContact C-N 3.31Å; G141-G143 PolarHBondContact O-N 3.36Å; G143-F145 PolarHBondContact O-N 3.49Å; G143-G146 PolarHBondContact O-N 3.03Å; G143-T147 PolarHBondContact O-N 3.26Å; G143-T147 PolarHBondContact O-OG1 2.84Å; G143-T147 VanDerWaalsContact O-OG1 3.07Å; G143-G175 CarbonylContact C-O 3.58Å; G143-G175 WeakPolarHBondContact CA-O 3.49Å
144	V	94.4	Very high	91.9	Very high	1 Å²	1	37.8 Å²	37.8	1%	0.006	19%	0.192	C	C	.	.	H	α-helix	trans	-61.8	-42.4	177.7	178	0	0	0	0	111.8	V48 L140 G141 A148 T179 W241	V48-V144 HydrophobicContact CG2-CG1 4.37Å; V48-V144 HydrophobicContact CG2-CG2 3.57Å; L140-V144 VanDerWaalsContact O-CG2 3.28Å; L140-V144 WeakPolarHBondContact O-CG2 3.46Å; L140-V144 PolarHBondContact O-N 3.42Å; L140-V144 VanDerWaalsContact O-N 3.11Å; G141-V144 PolarHBondContact O-N 3.3Å; V144-A148 WeakPolarHBondContact O-CB 3.3Å; V144-A148 PolarHBondContact O-N 2.92Å; V144-T179 HydrophobicContact CG2-CG2 3.95Å; V144-W241 HydrophobicContact CB-CE3 4.09Å; V144-W241 HydrophobicContact CB-CZ3 3.67Å; V144-W241 HydrophobicContact CG1-CE3 3.55Å; V144-W241 HydrophobicContact CG1-CZ3 3.69Å; V144-W241 HydrophobicContact CG2-CH2 4.3Å; V144-W241 HydrophobicContact CG2-CZ3 3.86Å
145	F	95.6	Very high	92.5	Very high	70 Å²	70	30.3 Å²	30.3	31%	0.307	17%	0.165	S	C	.	.	H	α-helix	trans	-63.4	-46.6	177.6	178.7	-111.1	0	0	0	112.4	G141 M142 G143 A148 V149 F242	G141-F145 WeakPolarHBondContact O-CB 3.49Å; G141-F145 PolarHBondContact O-N 3.13Å; M142-F145 HydrophobicContact CE-CD1 4.47Å; G143-F145 PolarHBondContact O-N 3.49Å; F145-A148 PolarHBondContact O-N 2.85Å; F145-V149 HydrophobicContact CD1-CG2 4.5Å; F145-V149 HydrophobicContact CD2-CG2 4.17Å; F145-V149 HydrophobicContact CE1-CG2 4.08Å; F145-V149 HydrophobicContact CE2-CG2 3.72Å; F145-V149 HydrophobicContact CZ-CG2 3.67Å; F145-V149 WeakPolarHBondContact O-CG2 3.37Å; F145-V149 PolarHBondContact O-N 3.3Å; F145-F242 HydrophobicContact CB-CB 4.14Å; F145-F242 HydrophobicContact CB-CD1 3.84Å; F145-F242 HydrophobicContact CB-CD2 3.72Å; F145-F242 HydrophobicContact CB-CE1 4.09Å; F145-F242 HydrophobicContact CB-CE2 3.97Å; F145-F242 HydrophobicContact CB-CG 3.63Å; F145-F242 HydrophobicContact CB-CZ 4.14Å; F145-F242 HydrophobicContact CD1-CE1 4.23Å; F145-F242 HydrophobicContact CD2-CB 4.18Å; F145-F242 AromaticContact CD2-CD1 3.42Å; F145-F242 HydrophobicContact CD2-CD1 3.42Å; F145-F242 VanDerWaalsContact CD2-CD1 3.42Å; F145-F242 AromaticContact CD2-CE1 3.92Å; F145-F242 HydrophobicContact CD2-CE1 3.92Å; F145-F242 AromaticContact CD2-CG 3.9Å; F145-F242 HydrophobicContact CD2-CG 3.9Å; F145-F242 HydrophobicContact CE2-CD1 4.1Å; F145-F242 HydrophobicContact CE2-CE1 4.44Å; F145-F242 AromaticContact CG-CD1 3.67Å; F145-F242 HydrophobicContact CG-CD1 3.67Å; F145-F242 HydrophobicContact CG-CD2 4.44Å; F145-F242 AromaticContact CG-CE1 3.8Å; F145-F242 HydrophobicContact CG-CE1 3.8Å; F145-F242 AromaticContact CG-CG 3.99Å; F145-F242 HydrophobicContact CG-CG 3.99Å; F145-F242 HydrophobicContact CG-CZ 4.25Å
146	G	94.8	Very high	93.2	Very high	27 Å²	27	35.6 Å²	35.6	28%	0.278	19%	0.192	S	C	.	.	H	α-helix	trans	-58.4	-49.4	177.3	0	0	0	0	0	111.3	M142 G143 A148 V149 L150	M142-G146 PolarHBondContact O-N 3.23Å; G143-G146 PolarHBondContact O-N 3.03Å; G146-A148 PolarHBondContact O-N 3.42Å; G146-V149 PolarHBondContact O-N 3.47Å; G146-L150 WeakPolarHBondContact O-CB 3.47Å; G146-L150 VanDerWaalsContact O-CG 3.23Å; G146-L150 WeakPolarHBondContact O-CG 3.47Å; G146-L150 PolarHBondContact O-N 2.94Å
147	T	95.4	Very high	93.6	Very high	2 Å²	2	35.9 Å²	35.9	1%	0.012	19%	0.194	C	C	.	.	H	α-helix	trans	-60.3	-45.1	175.8	-56.3	0	0	0	0	111.3	L51 G143 V149 L150 T151 E172 E176	L51-T147 HydrophobicContact CB-CG2 4.45Å; L51-T147 HydrophobicContact CD1-CG2 4.01Å; G143-T147 PolarHBondContact O-N 3.26Å; G143-T147 PolarHBondContact O-OG1 2.84Å; G143-T147 VanDerWaalsContact O-OG1 3.07Å; T147-V149 PolarHBondContact O-N 3.4Å; T147-L150 PolarHBondContact O-N 3.31Å; T147-T151 PolarHBondContact O-N 3.15Å; T147-T151 PolarHBondContact O-OG1 3.23Å; T147-E172 HydrophobicContact CG2-CB 4.02Å; T147-E172 HydrophobicContact CG2-CG 4.28Å; T147-E172 PolarHBondContact OG1-O 3.34Å; T147-E176 HydrophobicContact CG2-CB 4.48Å; T147-E176 PolarHBondContact OG1-N 3.43Å
148	A	95.7	Very high	93.6	Very high	0 Å²	0	33.7 Å²	33.7	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-61.6	-42.8	179.9	0	0	0	0	0	113.3	L51 V144 F145 G146 T151 V152	L51-A148 HydrophobicContact CD1-CB 4.29Å; V144-A148 WeakPolarHBondContact O-CB 3.3Å; V144-A148 PolarHBondContact O-N 2.92Å; F145-A148 PolarHBondContact O-N 2.85Å; G146-A148 PolarHBondContact O-N 3.42Å; A148-T151 PolarHBondContact O-N 2.94Å; A148-V152 WeakPolarHBondContact O-CG2 3.3Å; A148-V152 PolarHBondContact O-N 2.88Å; A148-V152 VanDerWaalsContact O-N 3.08Å
149	V	96.4	Very high	93.5	Very high	54 Å²	54	31.6 Å²	31.6	33%	0.327	19%	0.186	S	C	.	.	H	α-helix	trans	-64.8	-43.9	175.9	171.6	0	0	0	0	110.9	F145 G146 T147 T151 V152 L153	F145-V149 HydrophobicContact CD1-CG2 4.5Å; F145-V149 HydrophobicContact CD2-CG2 4.17Å; F145-V149 HydrophobicContact CE1-CG2 4.08Å; F145-V149 HydrophobicContact CE2-CG2 3.72Å; F145-V149 HydrophobicContact CZ-CG2 3.67Å; F145-V149 WeakPolarHBondContact O-CG2 3.37Å; F145-V149 PolarHBondContact O-N 3.3Å; G146-V149 PolarHBondContact O-N 3.47Å; T147-V149 PolarHBondContact O-N 3.4Å; V149-T151 VanDerWaalsContact C-N 3.28Å; V149-T151 PolarHBondContact O-N 3.46Å; V149-V152 WeakPolarHBondContact O-CB 3.37Å; V149-V152 PolarHBondContact O-N 2.81Å; V149-L153 HydrophobicContact CG1-CD1 4.44Å; V149-L153 WeakPolarHBondContact O-CG 3.23Å; V149-L153 PolarHBondContact O-N 3.15Å
150	L	96.1	Very high	93.5	Very high	37 Å²	37	34.7 Å²	34.7	19%	0.194	20%	0.204	C	C	.	.	H	α-helix	trans	-62	-38.1	175.8	-68.6	170.4	0	0	0	111.2	G146 T147 V152 L153 T154 L168 L171 E172	G146-L150 WeakPolarHBondContact O-CB 3.47Å; G146-L150 VanDerWaalsContact O-CG 3.23Å; G146-L150 WeakPolarHBondContact O-CG 3.47Å; G146-L150 PolarHBondContact O-N 2.94Å; T147-L150 PolarHBondContact O-N 3.31Å; L150-V152 PolarHBondContact O-N 3.16Å; L150-L153 CarbonylContact O-C 3.57Å; L150-L153 WeakPolarHBondContact O-CA 3.27Å; L150-L153 WeakPolarHBondContact O-CB 3.23Å; L150-L153 PolarHBondContact O-N 2.86Å; L150-T154 PolarHBondContact O-N 2.97Å; L150-L168 HydrophobicContact CB-CD2 4.36Å; L150-L168 HydrophobicContact CB-CG 4.36Å; L150-L168 HydrophobicContact CD2-CG 4.43Å; L150-L168 WeakPolarHBondContact O-CD2 3.37Å; L150-L171 HydrophobicContact CD1-CB 3.61Å; L150-E172 HydrophobicContact CB-CG 3.58Å; L150-E172 HydrophobicContact CD1-CG 4.28Å
151	T	94.9	Very high	93.4	Very high	0 Å²	0	35.7 Å²	35.7	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-63.3	-41	175.4	-57.5	0	0	0	0	112.2	L51 T147 A148 V149 L153 T154 E172 F231	L51-T151 HydrophobicContact CD2-CG2 3.77Å; T147-T151 PolarHBondContact O-N 3.15Å; T147-T151 PolarHBondContact O-OG1 3.23Å; A148-T151 PolarHBondContact O-N 2.94Å; V149-T151 VanDerWaalsContact C-N 3.28Å; V149-T151 PolarHBondContact O-N 3.46Å; T151-L153 PolarHBondContact O-N 3Å; T151-T154 WeakPolarHBondContact O-CB 3.39Å; T151-T154 PolarHBondContact O-N 3.07Å; T151-T154 PolarHBondContact O-OG1 2.92Å; T151-E172 WeakPolarHBondContact CA-OE1 3.32Å; T151-E172 WeakPolarHBondContact CB-OE1 3.32Å; T151-E172 PolarHBondContact N-OE1 3.42Å; T151-E172 VanDerWaalsContact N-OE1 3.13Å; T151-E172 PolarHBondContact OG1-OE1 3.44Å; T151-F231 HydrophobicContact CG2-CB 4.2Å; T151-F231 HydrophobicContact CG2-CD1 3.79Å; T151-F231 HydrophobicContact CG2-CG 4.49Å; T151-F231 WeakPolarHBondContact O-CB 3.45Å
152	V	95.9	Very high	93.3	Very high	49 Å²	49	37.5 Å²	37.5	30%	0.297	23%	0.229	S	C	.	.	H	α-helix	trans	-58.8	-32	171.6	171.1	0	0	0	0	111.8	A148 V149 L150 P155 Y232	A148-V152 WeakPolarHBondContact O-CG2 3.3Å; A148-V152 PolarHBondContact O-N 2.88Å; A148-V152 VanDerWaalsContact O-N 3.08Å; V149-V152 WeakPolarHBondContact O-CB 3.37Å; V149-V152 PolarHBondContact O-N 2.81Å; L150-V152 PolarHBondContact O-N 3.16Å; V152-P155 WeakPolarHBondContact O-CD 3.49Å; V152-Y232 HydrophobicContact CG1-CD1 4.01Å; V152-Y232 HydrophobicContact CG1-CE1 4.29Å; V152-Y232 VanDerWaalsContact O-CE1 3.25Å; V152-Y232 WeakPolarHBondContact O-CE1 3.14Å
153	L	95.2	Very high	93.3	Very high	77 Å²	77	43 Å²	43	40%	0.403	24%	0.244	S	C	.	.	H	α-helix	trans	-82.5	-9.1	177.7	-63.3	173.8	0	0	0	113.8	V149 L150 T151 L156 A157 L168	V149-L153 HydrophobicContact CG1-CD1 4.44Å; V149-L153 WeakPolarHBondContact O-CG 3.23Å; V149-L153 PolarHBondContact O-N 3.15Å; L150-L153 CarbonylContact O-C 3.57Å; L150-L153 WeakPolarHBondContact O-CA 3.27Å; L150-L153 WeakPolarHBondContact O-CB 3.23Å; L150-L153 PolarHBondContact O-N 2.86Å; T151-L153 PolarHBondContact O-N 3Å; L153-L156 WeakPolarHBondContact O-CB 3.38Å; L153-L156 PolarHBondContact O-N 3.3Å; L153-A157 PolarHBondContact O-N 3.09Å; L153-L168 HydrophobicContact CB-CD1 3.8Å
154	T	94.1	Very high	93.3	Very high	0 Å²	0	50.4 Å²	50.4	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-52.9	-48.9	-179.8	-78.7	0	0	0	0	112.8	L150 T151 L156 A157 A158 L165 L168 R169 E172 F231	L150-T154 PolarHBondContact O-N 2.97Å; T151-T154 WeakPolarHBondContact O-CB 3.39Å; T151-T154 PolarHBondContact O-N 3.07Å; T151-T154 PolarHBondContact O-OG1 2.92Å; T154-L156 VanDerWaalsContact C-N 3.27Å; T154-L156 PolarHBondContact O-N 2.98Å; T154-A157 PolarHBondContact O-N 3.08Å; T154-A157 VanDerWaalsContact O-N 3.17Å; T154-A158 WeakPolarHBondContact O-CB 3.13Å; T154-A158 PolarHBondContact O-N 3.49Å; T154-L165 HydrophobicContact CG2-CD1 3.82Å; T154-L168 WeakPolarHBondContact OG1-CD2 3.28Å; T154-R169 VanDerWaalsContact CG2-NH2 3.26Å; T154-R169 PolarHBondContact OG1-NH2 2.94Å; T154-E172 PolarHBondContact OG1-OE1 3.14Å; T154-F231 HydrophobicContact CG2-CD1 3.85Å; T154-F231 HydrophobicContact CG2-CD2 3.75Å; T154-F231 HydrophobicContact CG2-CE1 3.85Å; T154-F231 HydrophobicContact CG2-CE2 3.7Å; T154-F231 HydrophobicContact CG2-CG 3.81Å; T154-F231 HydrophobicContact CG2-CZ 3.76Å
155	P	92.9	Very high	93.3	Very high	13 Å²	13	50.4 Å²	50.4	8%	0.084	27%	0.269	C	S	.	.	H	α-helix	trans	-62.2	-35.9	-177.8	-23.9	35.2	0	0	0	113.2	V152 G159 W227 P228 F231 Y232	V152-P155 WeakPolarHBondContact O-CD 3.49Å; P155-G159 PolarHBondContact O-N 3.31Å; P155-W227 HydrophobicContact CB-CH2 3.99Å; P155-W227 HydrophobicContact CB-CZ3 3.79Å; P155-W227 HydrophobicContact CG-CZ3 4.07Å; P155-P228 HydrophobicContact CB-CB 4.03Å; P155-P228 HydrophobicContact CG-CB 4.11Å; P155-F231 HydrophobicContact CG-CB 3.86Å; P155-F231 HydrophobicContact CG-CD2 4.03Å; P155-F231 HydrophobicContact CG-CG 4.33Å; P155-Y232 HydrophobicContact CG-CE1 3.99Å; P155-Y232 HydrophobicContact CG-CE2 4.38Å
156	L	92.4	Very high	93.2	Very high	112 Å²	112	50.3 Å²	50.3	59%	0.586	27%	0.269	S	S	*	.	H	α-helix	trans	-66.1	-45.8	175.2	-178.5	67.6	0	0	0	110.9	L153 T154 A158 G159 L160	L153-L156 WeakPolarHBondContact O-CB 3.38Å; L153-L156 PolarHBondContact O-N 3.3Å; T154-L156 VanDerWaalsContact C-N 3.27Å; T154-L156 PolarHBondContact O-N 2.98Å; L156-A158 VanDerWaalsContact C-N 3.33Å; L156-A158 PolarHBondContact O-N 3.11Å; L156-G159 PolarHBondContact O-N 3.34Å; L156-L160 WeakPolarHBondContact O-CG 3.28Å; L156-L160 PolarHBondContact O-N 2.66Å; L156-L160 VanDerWaalsContact O-N 3.17Å
157	A	92.6	Very high	93.3	Very high	9 Å²	9	51.2 Å²	51.2	7%	0.074	27%	0.274	C	S	.	.	H	α-helix	trans	-64.1	-37.9	178.3	0	0	0	0	0	112.5	L153 T154 G159 L160 G161 W164 L168	L153-A157 PolarHBondContact O-N 3.09Å; T154-A157 PolarHBondContact O-N 3.08Å; T154-A157 VanDerWaalsContact O-N 3.17Å; A157-G159 VanDerWaalsContact C-N 3.29Å; A157-G159 PolarHBondContact O-N 3.47Å; A157-L160 PolarHBondContact O-N 3.34Å; A157-L160 VanDerWaalsContact O-N 3.17Å; A157-G161 PolarHBondContact O-N 3.02Å; A157-W164 HydrophobicContact CB-CB 4.39Å; A157-L168 HydrophobicContact CB-CB 4.29Å; A157-L168 HydrophobicContact CB-CD1 3.67Å
158	A	90.3	Very high	93.3	Very high	0 Å²	0	51.9 Å²	51.9	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-59.3	-40.9	173.4	0	0	0	0	0	111.5	M62 Y102 W104 T154 L156 L160 G161 L165 W227	M62-A158 HydrophobicContact CE-CB 3.73Å; Y102-A158 VanDerWaalsContact CE1-O 3.26Å; Y102-A158 WeakPolarHBondContact CE1-O 3.49Å; Y102-A158 HydrophobicContact CE2-CB 3.8Å; Y102-A158 VanDerWaalsContact OH-C 3.31Å; W104-A158 HydrophobicContact CH2-CB 4.14Å; T154-A158 WeakPolarHBondContact O-CB 3.13Å; T154-A158 PolarHBondContact O-N 3.49Å; L156-A158 VanDerWaalsContact C-N 3.33Å; L156-A158 PolarHBondContact O-N 3.11Å; A158-L160 VanDerWaalsContact C-N 3.31Å; A158-L160 PolarHBondContact O-N 2.96Å; A158-G161 PolarHBondContact O-N 3.45Å; A158-L165 HydrophobicContact CB-CD2 4.34Å; A158-W227 HydrophobicContact CB-CH2 3.8Å; A158-W227 HydrophobicContact CB-CZ3 4.46Å
159	G	88.1	Confident	93.2	Very high	52 Å²	52	52 Å²	52	54%	0.536	28%	0.278	S	S	.	.	H	α-helix	trans	-67	-27.4	176.2	0	0	0	0	0	114.3	Y102 P155 L156 A157	Y102-G159 VanDerWaalsContact OH-CA 3.28Å; Y102-G159 WeakPolarHBondContact OH-CA 3.36Å; Y102-G159 PolarHBondContact OH-N 3.28Å; Y102-G159 VanDerWaalsContact OH-N 3.13Å; P155-G159 PolarHBondContact O-N 3.31Å; L156-G159 PolarHBondContact O-N 3.34Å; A157-G159 VanDerWaalsContact C-N 3.29Å; A157-G159 PolarHBondContact O-N 3.47Å
160	L	89.9	Confident	93.1	Very high	112 Å²	112	50.6 Å²	50.6	59%	0.586	27%	0.271	S	S	*	.	H	α-helix	trans	-81.4	-18.8	176.3	-65	171.9	0	0	0	113	L156 A157 A158 W164	L156-L160 WeakPolarHBondContact O-CG 3.28Å; L156-L160 PolarHBondContact O-N 2.66Å; L156-L160 VanDerWaalsContact O-N 3.17Å; A157-L160 PolarHBondContact O-N 3.34Å; A157-L160 VanDerWaalsContact O-N 3.17Å; A158-L160 VanDerWaalsContact C-N 3.31Å; A158-L160 PolarHBondContact O-N 2.96Å; L160-W164 HydrophobicContact CB-CB 4.21Å; L160-W164 HydrophobicContact CB-CG 4Å
161	G	89.9	Confident	93	Very high	25 Å²	25	53.2 Å²	53.2	26%	0.258	29%	0.285	S	S	.	.			trans	126.6	166.3	174	0	0	0	0	0	114.6	A157 A158 R163 W164 L165	A157-G161 PolarHBondContact O-N 3.02Å; A158-G161 PolarHBondContact O-N 3.45Å; G161-R163 VanDerWaalsContact C-N 3.29Å; G161-R163 PolarHBondContact O-N 3.49Å; G161-W164 PolarHBondContact O-N 3.47Å; G161-W164 VanDerWaalsContact O-N 3.13Å; G161-L165 PolarHBondContact O-N 2.97Å
162	S	89.1	Confident	93	Very high	40 Å²	40	53.3 Å²	53.3	28%	0.28	29%	0.285	S	S	.	.	H	α-helix	trans	-58.5	-34.6	-173.8	56.7	0	0	0	0	114	L112 W164 L165 F166	L112-S162 WeakPolarHBondContact CD2-O 3.36Å; S162-W164 PolarHBondContact O-N 3.37Å; S162-L165 PolarHBondContact O-N 3.43Å; S162-F166 WeakPolarHBondContact O-CB 3.46Å; S162-F166 PolarHBondContact O-N 3.37Å
163	R	92.3	Very high	92.9	Very high	216 Å²	216	51 Å²	51	82%	0.815	27%	0.271	S	S	*	.	H	α-helix	trans	-65	-38.7	178.5	-63.1	-179.9	-174.8	167.3	1.7	112.8	G161 A167	G161-R163 VanDerWaalsContact C-N 3.29Å; G161-R163 PolarHBondContact O-N 3.49Å; R163-A167 PolarHBondContact O-N 3.26Å; R163-A167 VanDerWaalsContact O-N 3.08Å
164	W	93.8	Very high	92.8	Very high	163 Å²	163	53 Å²	53	62%	0.617	28%	0.277	S	S	*	.	H	α-helix	trans	-72.1	-39.9	177.5	-67.8	107.4	0	0	0	111.1	A157 L160 G161 S162 F166 A167 L168	A157-W164 HydrophobicContact CB-CB 4.39Å; L160-W164 HydrophobicContact CB-CB 4.21Å; L160-W164 HydrophobicContact CB-CG 4Å; G161-W164 PolarHBondContact O-N 3.47Å; G161-W164 VanDerWaalsContact O-N 3.13Å; S162-W164 PolarHBondContact O-N 3.37Å; W164-F166 VanDerWaalsContact C-N 3.35Å; W164-A167 PolarHBondContact O-N 2.86Å; W164-L168 WeakPolarHBondContact O-CB 3.13Å; W164-L168 PolarHBondContact O-N 3.2Å
165	L	93.6	Very high	92.6	Very high	0 Å²	0	53.5 Å²	53.5	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-61.5	-43.6	173	-175.8	59.9	0	0	0	111.3	M62 W104 L112 T154 A158 G161 S162 A167 L168 R169	M62-L165 HydrophobicContact CE-CD2 4.24Å; W104-L165 HydrophobicContact CH2-CD2 3.51Å; W104-L165 HydrophobicContact CZ2-CD2 4.15Å; W104-L165 HydrophobicContact CZ3-CD2 4.01Å; L112-L165 HydrophobicContact CD1-CD2 3.98Å; L112-L165 HydrophobicContact CD2-CB 4.01Å; L112-L165 HydrophobicContact CD2-CD2 4.01Å; L112-L165 HydrophobicContact CD2-CG 3.89Å; T154-L165 HydrophobicContact CG2-CD1 3.82Å; A158-L165 HydrophobicContact CB-CD2 4.34Å; G161-L165 PolarHBondContact O-N 2.97Å; S162-L165 PolarHBondContact O-N 3.43Å; L165-A167 PolarHBondContact O-N 2.61Å; L165-L168 PolarHBondContact O-N 2.9Å; L165-R169 HydrophobicContact CD1-CG 4.29Å; L165-R169 HydrophobicContact CG-CG 4.42Å; L165-R169 WeakPolarHBondContact O-CB 3.47Å; L165-R169 WeakPolarHBondContact O-CG 3.44Å; L165-R169 PolarHBondContact O-N 3.03Å
166	F	94.4	Very high	92.5	Very high	69 Å²	69	53 Å²	53	30%	0.303	28%	0.279	S	S	.	.	H	α-helix	trans	-57.5	-49.5	174.8	-179.3	-86.5	0	0	0	112.1	W111 L112 A115 F118 S162 W164 L168 R169 A170	W111-F166 HydrophobicContact CE3-CE2 4.2Å; L112-F166 HydrophobicContact CD2-CB 3.98Å; A115-F166 HydrophobicContact CB-CD2 3.48Å; A115-F166 VanDerWaalsContact CB-CD2 3.48Å; A115-F166 HydrophobicContact CB-CE2 3.55Å; A115-F166 HydrophobicContact CB-CG 4.1Å; A115-F166 HydrophobicContact CB-CZ 4.23Å; F118-F166 HydrophobicContact CD2-CZ 4.35Å; F118-F166 HydrophobicContact CE2-CZ 4.5Å; S162-F166 WeakPolarHBondContact O-CB 3.46Å; S162-F166 PolarHBondContact O-N 3.37Å; W164-F166 VanDerWaalsContact C-N 3.35Å; F166-L168 PolarHBondContact O-N 3.08Å; F166-R169 PolarHBondContact O-N 2.98Å; F166-A170 PolarHBondContact O-N 3.29Å
167	A	95.3	Very high	92.3	Very high	45 Å²	45	47.6 Å²	47.6	37%	0.372	25%	0.251	S	S	.	.	H	α-helix	trans	-62.4	-43.1	179.3	0	0	0	0	0	111.9	R163 W164 L165 R169 A170 L171	R163-A167 PolarHBondContact O-N 3.26Å; R163-A167 VanDerWaalsContact O-N 3.08Å; W164-A167 PolarHBondContact O-N 2.86Å; L165-A167 PolarHBondContact O-N 2.61Å; A167-R169 VanDerWaalsContact C-N 3.35Å; A167-R169 PolarHBondContact O-N 3.04Å; A167-A170 PolarHBondContact O-N 3.26Å; A167-L171 WeakPolarHBondContact O-CG 3.24Å; A167-L171 PolarHBondContact O-N 3.07Å
168	L	95.3	Very high	92.1	Very high	16 Å²	16	47.9 Å²	47.9	8%	0.084	25%	0.252	C	S	.	.	H	α-helix	trans	-62.6	-42.5	176.8	-175.2	150.7	0	0	0	111.3	L150 L153 T154 A157 W164 L165 F166 L171 E172	L150-L168 HydrophobicContact CB-CD2 4.36Å; L150-L168 HydrophobicContact CB-CG 4.36Å; L150-L168 HydrophobicContact CD2-CG 4.43Å; L150-L168 WeakPolarHBondContact O-CD2 3.37Å; L153-L168 HydrophobicContact CB-CD1 3.8Å; T154-L168 WeakPolarHBondContact OG1-CD2 3.28Å; A157-L168 HydrophobicContact CB-CB 4.29Å; A157-L168 HydrophobicContact CB-CD1 3.67Å; W164-L168 WeakPolarHBondContact O-CB 3.13Å; W164-L168 PolarHBondContact O-N 3.2Å; L165-L168 PolarHBondContact O-N 2.9Å; F166-L168 PolarHBondContact O-N 3.08Å; L168-L171 CarbonylContact O-C 3.27Å; L168-L171 WeakPolarHBondContact O-CB 3.33Å; L168-L171 PolarHBondContact O-N 3.27Å; L168-L171 VanDerWaalsContact O-N 3.15Å; L168-E172 HydrophobicContact CD2-CG 3.99Å; L168-E172 WeakPolarHBondContact CD2-OE1 3.42Å; L168-E172 WeakPolarHBondContact O-CG 3.44Å; L168-E172 PolarHBondContact O-N 3.24Å
169	R	93.9	Very high	92.1	Very high	4 Å²	4	47.9 Å²	47.9	2%	0.015	25%	0.252	C	S	.	.	H	α-helix	trans	-63	-41.9	176.7	-72.4	-73.7	148.2	162.9	-2.4	112.7	L55 A115 F116 T154 L165 F166 A167 L171 E172 G173	L55-R169 HydrophobicContact CD2-CG 4.45Å; A115-R169 HydrophobicContact CB-CB 3.62Å; F116-R169 WeakPolarHBondContact CA-O 3.28Å; T154-R169 VanDerWaalsContact CG2-NH2 3.26Å; T154-R169 PolarHBondContact OG1-NH2 2.94Å; L165-R169 HydrophobicContact CD1-CG 4.29Å; L165-R169 HydrophobicContact CG-CG 4.42Å; L165-R169 WeakPolarHBondContact O-CB 3.47Å; L165-R169 WeakPolarHBondContact O-CG 3.44Å; L165-R169 PolarHBondContact O-N 3.03Å; F166-R169 PolarHBondContact O-N 2.98Å; A167-R169 VanDerWaalsContact C-N 3.35Å; A167-R169 PolarHBondContact O-N 3.04Å; R169-L171 VanDerWaalsContact C-N 3.29Å; R169-L171 PolarHBondContact O-N 3.38Å; R169-E172 WeakPolarHBondContact CD-OE2 3.44Å; R169-E172 IonicContact CZ-OE2 2.71Å; R169-E172 VanDerWaalsContact CZ-OE2 3.25Å; R169-E172 IonicContact NE-OE2 3.32Å; R169-E172 PolarHBondContact NE-OE2 3.38Å; R169-E172 VanDerWaalsContact NE-OE2 3.09Å; R169-E172 IonicContact NH1-OE2 3.01Å; R169-E172 PolarHBondContact NH1-OE2 3.35Å; R169-E172 IonicContact NH2-OE2 3.26Å; R169-E172 WeakPolarHBondContact O-CB 3.31Å; R169-E172 PolarHBondContact O-N 3.27Å; R169-G173 PolarHBondContact O-N 2.76Å
170	A	94.9	Very high	91.9	Very high	23 Å²	23	47.2 Å²	47.2	19%	0.19	23%	0.234	C	C	.	.	H	α-helix	trans	-62.2	-38.5	173.7	0	0	0	0	0	111.4	A115 G119 F166 A167 G173 F174	A115-A170 WeakPolarHBondContact O-CA 3.18Å; G119-A170 WeakPolarHBondContact CA-O 3.36Å; F166-A170 PolarHBondContact O-N 3.29Å; A167-A170 PolarHBondContact O-N 3.26Å; A170-G173 PolarHBondContact O-N 3.32Å; A170-F174 WeakPolarHBondContact O-CB 3.43Å; A170-F174 PolarHBondContact O-N 2.93Å
171	L	95.1	Very high	91.5	Very high	93 Å²	93	43.1 Å²	43.1	49%	0.487	21%	0.214	S	C	.	.	H	α-helix	trans	-68.9	-36.7	175.1	-69.5	172.1	0	0	0	113	L150 A167 L168 R169 G173 F174 G175	L150-L171 HydrophobicContact CD1-CB 3.61Å; A167-L171 WeakPolarHBondContact O-CG 3.24Å; A167-L171 PolarHBondContact O-N 3.07Å; L168-L171 CarbonylContact O-C 3.27Å; L168-L171 WeakPolarHBondContact O-CB 3.33Å; L168-L171 PolarHBondContact O-N 3.27Å; L168-L171 VanDerWaalsContact O-N 3.15Å; R169-L171 VanDerWaalsContact C-N 3.29Å; R169-L171 PolarHBondContact O-N 3.38Å; L171-G173 VanDerWaalsContact C-N 3.34Å; L171-F174 WeakPolarHBondContact O-CB 3.41Å; L171-F174 PolarHBondContact O-N 3.17Å; L171-G175 PolarHBondContact O-N 3.35Å
172	E	94.5	Very high	91.4	Very high	1 Å²	1	42 Å²	42	1%	0.005	20%	0.202	C	C	.	.	H	α-helix	trans	-58.6	-47.7	172.4	-76.4	178.5	160.8	0	0	110.9	F116 T147 L150 T151 T154 L168 R169 F174 G175 E176	F116-E172 HydrophobicContact CD2-CB 4.27Å; T147-E172 HydrophobicContact CG2-CB 4.02Å; T147-E172 HydrophobicContact CG2-CG 4.28Å; T147-E172 PolarHBondContact OG1-O 3.34Å; L150-E172 HydrophobicContact CB-CG 3.58Å; L150-E172 HydrophobicContact CD1-CG 4.28Å; T151-E172 WeakPolarHBondContact CA-OE1 3.32Å; T151-E172 WeakPolarHBondContact CB-OE1 3.32Å; T151-E172 PolarHBondContact N-OE1 3.42Å; T151-E172 VanDerWaalsContact N-OE1 3.13Å; T151-E172 PolarHBondContact OG1-OE1 3.44Å; T154-E172 PolarHBondContact OG1-OE1 3.14Å; L168-E172 HydrophobicContact CD2-CG 3.99Å; L168-E172 WeakPolarHBondContact CD2-OE1 3.42Å; L168-E172 WeakPolarHBondContact O-CG 3.44Å; L168-E172 PolarHBondContact O-N 3.24Å; R169-E172 WeakPolarHBondContact CD-OE2 3.44Å; R169-E172 IonicContact CZ-OE2 2.71Å; R169-E172 VanDerWaalsContact CZ-OE2 3.25Å; R169-E172 IonicContact NE-OE2 3.32Å; R169-E172 PolarHBondContact NE-OE2 3.38Å; R169-E172 VanDerWaalsContact NE-OE2 3.09Å; R169-E172 IonicContact NH1-OE2 3.01Å; R169-E172 PolarHBondContact NH1-OE2 3.35Å; R169-E172 IonicContact NH2-OE2 3.26Å; R169-E172 WeakPolarHBondContact O-CB 3.31Å; R169-E172 PolarHBondContact O-N 3.27Å; E172-F174 VanDerWaalsContact C-N 3.34Å; E172-F174 PolarHBondContact O-N 3.15Å; E172-G175 PolarHBondContact O-N 3.41Å; E172-E176 WeakPolarHBondContact O-CB 3.42Å; E172-E176 PolarHBondContact O-N 3Å
173	G	93.2	Very high	91.4	Very high	0 Å²	0	40.1 Å²	40.1	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-61.4	-40.6	175.9	0	0	0	0	0	113.3	F116 Y120 R169 A170 L171 E176 G177	F116-G173 VanDerWaalsContact CE2-CA 3.48Å; F116-G173 VanDerWaalsContact O-CA 3.31Å; F116-G173 WeakPolarHBondContact O-CA 3.32Å; Y120-G173 VanDerWaalsContact CA-O 3.24Å; Y120-G173 WeakPolarHBondContact CA-O 3.45Å; Y120-G173 PolarHBondContact N-O 2.78Å; R169-G173 PolarHBondContact O-N 2.76Å; A170-G173 PolarHBondContact O-N 3.32Å; L171-G173 VanDerWaalsContact C-N 3.34Å; G173-E176 PolarHBondContact O-N 3.14Å; G173-G177 PolarHBondContact O-N 3.42Å
174	F	92.9	Very high	90.9	Very high	119 Å²	119	32.7 Å²	32.7	52%	0.522	16%	0.164	S	C	.	.	H	α-helix	trans	-59.7	-45.1	174.9	-178.9	-80.8	0	0	0	111.6	T123 A170 L171 E172 E176	T123-F174 HydrophobicContact CG2-CB 4.19Å; T123-F174 HydrophobicContact CG2-CD1 3.92Å; T123-F174 HydrophobicContact CG2-CD2 3.12Å; T123-F174 HydrophobicContact CG2-CE1 4.01Å; T123-F174 HydrophobicContact CG2-CE2 3.22Å; T123-F174 HydrophobicContact CG2-CG 3.48Å; T123-F174 VanDerWaalsContact CG2-CG 3.48Å; T123-F174 HydrophobicContact CG2-CZ 3.67Å; T123-F174 WeakPolarHBondContact CG2-O 3.44Å; T123-F174 PolarHBondContact OG1-O 3.09Å; A170-F174 WeakPolarHBondContact O-CB 3.43Å; A170-F174 PolarHBondContact O-N 2.93Å; L171-F174 WeakPolarHBondContact O-CB 3.41Å; L171-F174 PolarHBondContact O-N 3.17Å; E172-F174 VanDerWaalsContact C-N 3.34Å; E172-F174 PolarHBondContact O-N 3.15Å; F174-E176 VanDerWaalsContact C-N 3.31Å; F174-E176 PolarHBondContact O-N 3.09Å
175	G	91	Very high	90.4	Very high	12 Å²	12	25.6 Å²	25.6	12%	0.124	14%	0.141	C	C	.	.	H	α-helix	trans	-64.4	-36.3	175.2	0	0	0	0	0	112.6	G143 L171 E172 V178	G143-G175 CarbonylContact C-O 3.58Å; G143-G175 WeakPolarHBondContact CA-O 3.49Å; L171-G175 PolarHBondContact O-N 3.35Å; E172-G175 PolarHBondContact O-N 3.41Å; G175-V178 WeakPolarHBondContact O-CG2 3.42Å
176	E	90.8	Very high	90	Very high	1 Å²	1	25.7 Å²	25.7	1%	0.005	14%	0.141	C	C	.	.	H	α-helix	trans	-82.9	-25.8	-174.6	-155.7	176.5	126	0	0	113.3	V48 R52 F116 Y120 T147 E172 G173 F174 V178 T179	V48-E176 HydrophobicContact CG1-CG 3.58Å; V48-E176 WeakPolarHBondContact CG1-OE1 3.23Å; V48-E176 HydrophobicContact CG2-CG 4.47Å; R52-E176 IonicContact CZ-OE1 2.91Å; R52-E176 VanDerWaalsContact CZ-OE1 3.26Å; R52-E176 IonicContact NE-OE1 3.03Å; R52-E176 PolarHBondContact NE-OE1 3.36Å; R52-E176 IonicContact NH2-OE1 3.29Å; R52-E176 PolarHBondContact NH2-OE1 2.98Å; F116-E176 HydrophobicContact CE2-CB 4.04Å; F116-E176 VanDerWaalsContact CE2-OE2 3.22Å; F116-E176 WeakPolarHBondContact CE2-OE2 3.43Å; F116-E176 HydrophobicContact CZ-CB 3.84Å; F116-E176 HydrophobicContact CZ-CG 4.09Å; F116-E176 WeakPolarHBondContact CZ-OE1 3.14Å; F116-E176 WeakPolarHBondContact CZ-OE2 3.47Å; Y120-E176 HydrophobicContact CD2-CB 4.32Å; T147-E176 HydrophobicContact CG2-CB 4.48Å; T147-E176 PolarHBondContact OG1-N 3.43Å; E172-E176 WeakPolarHBondContact O-CB 3.42Å; E172-E176 PolarHBondContact O-N 3Å; G173-E176 PolarHBondContact O-N 3.14Å; F174-E176 VanDerWaalsContact C-N 3.31Å; F174-E176 PolarHBondContact O-N 3.09Å; E176-V178 PolarHBondContact O-N 3.19Å; E176-V178 VanDerWaalsContact O-N 3.13Å; E176-T179 HydrophobicContact CG-CG2 4.24Å; E176-T179 WeakPolarHBondContact O-CB 3.23Å; E176-T179 VanDerWaalsContact O-CG2 3.28Å; E176-T179 WeakPolarHBondContact O-CG2 3.35Å; E176-T179 PolarHBondContact O-N 3.09Å; E176-T179 PolarHBondContact O-OG1 3.41Å
177	G	87.7	Confident	89.6	Confident	0 Å²	0	22.5 Å²	22.5	0%	0	13%	0.127	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64.7	-18.3	-176.6	0	0	0	0	0	115.1	Y120 T123 Q124 G173	Y120-G177 VanDerWaalsContact CE2-CA 3.42Å; T123-G177 VanDerWaalsContact OG1-CA 3.29Å; T123-G177 WeakPolarHBondContact OG1-CA 3.48Å; Q124-G177 WeakPolarHBondContact CG-O 3.08Å; G173-G177 PolarHBondContact O-N 3.42Å
178	V	88.3	Confident	88.8	Confident	15 Å²	15	23.7 Å²	23.7	9%	0.091	13%	0.13	C	C	.	.	T	Hydrogen-bonded Turn	trans	-84	-12.1	175.6	-53.1	0	0	0	0	113.5	F139 G175 E176 A182	F139-V178 HydrophobicContact CB-CG2 4.34Å; F139-V178 HydrophobicContact CD1-CB 4.46Å; F139-V178 HydrophobicContact CD1-CG1 4.48Å; F139-V178 WeakPolarHBondContact O-CG2 3.3Å; G175-V178 WeakPolarHBondContact O-CG2 3.42Å; E176-V178 PolarHBondContact O-N 3.19Å; E176-V178 VanDerWaalsContact O-N 3.13Å; V178-A182 WeakPolarHBondContact O-CB 3.38Å; V178-A182 PolarHBondContact O-N 3.09Å
179	T	89	Confident	88.1	Confident	0 Å²	0	27.2 Å²	27.2	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-63.6	-53.8	-170.9	55.2	0	0	0	0	113.2	V48 V144 E176 A182 M183	V48-T179 HydrophobicContact CG2-CG2 4.2Å; V144-T179 HydrophobicContact CG2-CG2 3.95Å; E176-T179 HydrophobicContact CG-CG2 4.24Å; E176-T179 WeakPolarHBondContact O-CB 3.23Å; E176-T179 VanDerWaalsContact O-CG2 3.28Å; E176-T179 WeakPolarHBondContact O-CG2 3.35Å; E176-T179 PolarHBondContact O-N 3.09Å; E176-T179 PolarHBondContact O-OG1 3.41Å; T179-A182 PolarHBondContact O-N 2.82Å; T179-M183 WeakPolarHBondContact O-CB 3.36Å; T179-M183 PolarHBondContact O-N 2.8Å
180	F	84.4	Confident	87.7	Confident	38 Å²	38	27.1 Å²	27.1	17%	0.167	14%	0.142	C	C	.	.	H	α-helix	trans	-63.7	-48.9	-179.8	-82.7	-84.4	0	0	0	113.3	I45 Y49 Y120 A182 M183 M184	I45-F180 HydrophobicContact CG2-CZ 4.41Å; Y49-F180 AromaticContact CE2-CE2 3.8Å; Y49-F180 HydrophobicContact CE2-CE2 3.8Å; Y49-F180 AromaticContact CE2-CZ 3.65Å; Y49-F180 HydrophobicContact CE2-CZ 3.65Å; Y120-F180 VanDerWaalsContact OH-CD2 3.23Å; Y120-F180 WeakPolarHBondContact OH-CD2 3.43Å; F180-A182 VanDerWaalsContact C-N 3.32Å; F180-A182 PolarHBondContact O-N 2.89Å; F180-M183 HydrophobicContact CD1-CE 3.99Å; F180-M183 HydrophobicContact CE1-CE 4.43Å; F180-M183 WeakPolarHBondContact O-CB 3.36Å; F180-M183 PolarHBondContact O-N 3.06Å; F180-M184 PolarHBondContact O-N 3.11Å; F180-M184 VanDerWaalsContact O-N 3.08Å
181	P	82.9	Confident	87.2	Confident	26 Å²	26	26 Å²	26	17%	0.169	13%	0.133	C	C	.	.	H	α-helix	trans	-60.1	-40.8	175.5	-23.7	33.1	0	0	0	112.9	Q124 M184 A185	Q124-P181 WeakPolarHBondContact O-CG 3.35Å; P181-M184 PolarHBondContact O-N 2.78Å; P181-A185 WeakPolarHBondContact O-CB 3.3Å; P181-A185 PolarHBondContact O-N 2.89Å
182	A	87	Confident	86.6	Confident	0 Å²	0	21.6 Å²	21.6	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-66.4	-37.4	177.4	0	0	0	0	0	112.4	A131 F139 L140 V178 T179 F180 A185 M186	A131-A182 HydrophobicContact CB-CB 3.83Å; F139-A182 HydrophobicContact CB-CB 3.99Å; L140-A182 HydrophobicContact CB-CB 3.84Å; L140-A182 HydrophobicContact CD1-CB 4.46Å; V178-A182 WeakPolarHBondContact O-CB 3.38Å; V178-A182 PolarHBondContact O-N 3.09Å; T179-A182 PolarHBondContact O-N 2.82Å; F180-A182 VanDerWaalsContact C-N 3.32Å; F180-A182 PolarHBondContact O-N 2.89Å; A182-A185 PolarHBondContact O-N 2.92Å; A182-M186 WeakPolarHBondContact O-CG 3.38Å; A182-M186 PolarHBondContact O-N 3.3Å
183	M	88.4	Confident	85.6	Confident	2 Å²	2	25.5 Å²	25.5	1%	0.01	14%	0.135	C	C	.	.	H	α-helix	trans	-59	-48	173	-178.3	-175.6	70.4	0	0	111	M41 I45 L140 T179 F180 M186 W187	M41-M183 HydrophobicContact CE-CG 4.48Å; M41-M183 HydrophobicContact SD-CG 3.77Å; I45-M183 HydrophobicContact CD1-SD 4.3Å; I45-M183 HydrophobicContact CG1-SD 4.11Å; L140-M183 HydrophobicContact CD1-CB 3.83Å; T179-M183 WeakPolarHBondContact O-CB 3.36Å; T179-M183 PolarHBondContact O-N 2.8Å; F180-M183 HydrophobicContact CD1-CE 3.99Å; F180-M183 HydrophobicContact CE1-CE 4.43Å; F180-M183 WeakPolarHBondContact O-CB 3.36Å; F180-M183 PolarHBondContact O-N 3.06Å; M183-M186 PolarHBondContact O-N 3.34Å; M183-W187 VanDerWaalsContact O-CD1 3.25Å; M183-W187 PolarHBondContact O-N 3.07Å
184	M	83.1	Confident	84.7	Confident	59 Å²	59	33.1 Å²	33.1	29%	0.291	18%	0.175	S	C	.	.	H	α-helix	trans	-63.6	-43.3	177.6	-65.3	-57.6	174.7	0	0	111.4	F180 P181 M186 W187 T188 I200 L428	F180-M184 PolarHBondContact O-N 3.11Å; F180-M184 VanDerWaalsContact O-N 3.08Å; P181-M184 PolarHBondContact O-N 2.78Å; M184-M186 VanDerWaalsContact C-N 3.29Å; M184-M186 PolarHBondContact O-N 3.49Å; M184-W187 PolarHBondContact O-N 3.27Å; M184-W187 VanDerWaalsContact O-N 3.15Å; M184-T188 WeakPolarHBondContact O-CG2 3.34Å; M184-T188 PolarHBondContact O-N 2.99Å; M184-I200 HydrophobicContact CE-CG2 3.77Å; M184-I200 HydrophobicContact SD-CD1 4.21Å; M184-I200 HydrophobicContact SD-CG1 4.44Å; M184-I200 HydrophobicContact SD-CG2 4.04Å; M184-L428 HydrophobicContact CE-CD2 4.1Å
185	A	81.9	Confident	84	Confident	15 Å²	15	28.2 Å²	28.2	12%	0.124	15%	0.153	C	C	.	.	H	α-helix	trans	-58	-40.8	175.8	0	0	0	0	0	111.9	A131 P181 A182 T188	A131-A185 HydrophobicContact CB-CB 4.26Å; P181-A185 WeakPolarHBondContact O-CB 3.3Å; P181-A185 PolarHBondContact O-N 2.89Å; A182-A185 PolarHBondContact O-N 2.92Å; A185-T188 PolarHBondContact O-N 3.07Å; A185-T188 PolarHBondContact O-OG1 3.31Å
186	M	85.3	Confident	83.5	Confident	2 Å²	2	31.9 Å²	31.9	1%	0.01	16%	0.164	C	C	.	.	H	α-helix	trans	-65	-43.5	174.8	-73.2	-166.4	69.5	0	0	112.5	L37 M41 A182 M183 M184 T188 R189 W190 W245 V249	L37-M186 HydrophobicContact CD1-CE 3.93Å; L37-M186 HydrophobicContact CD2-CE 4.17Å; M41-M186 HydrophobicContact CE-CB 3.51Å; M41-M186 HydrophobicContact CE-CE 3.85Å; M41-M186 HydrophobicContact CE-CG 4.03Å; M41-M186 HydrophobicContact CE-SD 3.44Å; M41-M186 WeakPolarHBondContact CE-SD 3.33Å; A182-M186 WeakPolarHBondContact O-CG 3.38Å; A182-M186 PolarHBondContact O-N 3.3Å; M183-M186 PolarHBondContact O-N 3.34Å; M184-M186 VanDerWaalsContact C-N 3.29Å; M184-M186 PolarHBondContact O-N 3.49Å; M186-T188 PolarHBondContact O-N 3.32Å; M186-R189 PolarHBondContact O-N 2.87Å; M186-W190 PolarHBondContact O-N 3.43Å; M186-W245 HydrophobicContact CE-CH2 4.1Å; M186-W245 HydrophobicContact CE-CZ2 4.18Å; M186-W245 HydrophobicContact SD-CH2 3.69Å; M186-W245 HydrophobicContact SD-CZ2 3.6Å; M186-W245 VanDerWaalsContact SD-CZ2 3.6Å; M186-V249 HydrophobicContact CE-CG1 3.63Å
187	W	86.2	Confident	82.8	Confident	2 Å²	2	36.1 Å²	36.1	1%	0.008	19%	0.193	C	C	.	.	H	α-helix	trans	-64.2	-22.5	176.9	-74.6	124.4	0	0	0	113.3	L37 A38 M41 M183 M184 R189 W190 A191 L199 I200 S203	L37-W187 HydrophobicContact CB-CH2 4.43Å; L37-W187 HydrophobicContact CD2-CH2 4.2Å; L37-W187 HydrophobicContact CD2-CZ3 4.27Å; L37-W187 HydrophobicContact CG-CH2 4.23Å; A38-W187 HydrophobicContact CB-CH2 3.75Å; A38-W187 HydrophobicContact CB-CZ2 3.76Å; M41-W187 VanDerWaalsContact SD-CE2 3.57Å; M41-W187 HydrophobicContact SD-CZ2 3.61Å; M41-W187 PolarHBondContact SD-NE1 3.2Å; M183-W187 VanDerWaalsContact O-CD1 3.25Å; M183-W187 PolarHBondContact O-N 3.07Å; M184-W187 PolarHBondContact O-N 3.27Å; M184-W187 VanDerWaalsContact O-N 3.15Å; W187-R189 PolarHBondContact O-N 2.96Å; W187-W190 HydrophobicContact CE3-CB 4Å; W187-W190 HydrophobicContact CZ3-CB 4.07Å; W187-A191 HydrophobicContact CB-CB 4.29Å; W187-A191 HydrophobicContact CD2-CB 4.23Å; W187-A191 HydrophobicContact CE3-CB 3.46Å; W187-A191 VanDerWaalsContact CE3-CB 3.46Å; W187-A191 HydrophobicContact CZ3-CB 4.21Å; W187-A191 WeakPolarHBondContact O-CB 3.42Å; W187-A191 PolarHBondContact O-N 3.4Å; W187-L199 HydrophobicContact CD2-CB 4.26Å; W187-L199 HydrophobicContact CE3-CB 4.02Å; W187-L199 HydrophobicContact CE3-CD1 4.23Å; W187-L199 HydrophobicContact CH2-CB 3.74Å; W187-L199 HydrophobicContact CH2-CD1 4.26Å; W187-L199 HydrophobicContact CH2-CD2 3.96Å; W187-L199 HydrophobicContact CH2-CG 4.19Å; W187-L199 HydrophobicContact CZ2-CB 3.97Å; W187-L199 HydrophobicContact CZ3-CB 3.76Å; W187-L199 HydrophobicContact CZ3-CD1 3.7Å; W187-L199 HydrophobicContact CZ3-CD2 4.24Å; W187-L199 HydrophobicContact CZ3-CG 4.1Å; W187-I200 HydrophobicContact CB-CD1 4.38Å; W187-I200 HydrophobicContact CB-CG1 4.06Å; W187-I200 HydrophobicContact CG-CG1 3.84Å; W187-S203 WeakPolarHBondContact CZ2-OG 3.35Å; W187-S203 PolarHBondContact NE1-OG 3.06Å
188	T	79.1	Confident	82.6	Confident	70 Å²	70	42.3 Å²	42.3	43%	0.429	22%	0.221	S	C	.	.	H	α-helix	trans	-61.4	-31.3	171.7	71.6	0	0	0	0	113.2	M184 A185 M186	M184-T188 WeakPolarHBondContact O-CG2 3.34Å; M184-T188 PolarHBondContact O-N 2.99Å; A185-T188 PolarHBondContact O-N 3.07Å; A185-T188 PolarHBondContact O-OG1 3.31Å; M186-T188 PolarHBondContact O-N 3.32Å
189	R	80.3	Confident	82.4	Confident	89 Å²	89	41.9 Å²	41.9	34%	0.336	22%	0.218	S	C	.	.	H	α-helix	trans	-99.5	-22.9	-177.4	-57.4	-176.7	-175.1	-178.3	1.9	113.7	G132 M186 W187 P253 I271	G132-R189 PolarHBondContact O-NH2 3.41Å; M186-R189 PolarHBondContact O-N 2.87Å; W187-R189 PolarHBondContact O-N 2.96Å; R189-P253 WeakPolarHBondContact O-CG 3.25Å; R189-I271 WeakPolarHBondContact O-CD1 3.31Å
190	W	85.4	Confident	82.2	Confident	2 Å²	2	43.9 Å²	43.9	1%	0.008	23%	0.228	C	C	.	.	H	α-helix	trans	-108.3	-23.7	-171.8	-82.7	84.4	0	0	0	115.3	A33 R34 L37 M186 W187 P192 S250 D251 P253 H256 I259	A33-W190 HydrophobicContact CB-CZ3 4.21Å; R34-W190 WeakPolarHBondContact CD-O 3.44Å; R34-W190 HydrophobicContact CG-CE3 4.08Å; L37-W190 HydrophobicContact CD2-CB 3.91Å; L37-W190 HydrophobicContact CD2-CD2 3.52Å; L37-W190 HydrophobicContact CD2-CE3 3.8Å; L37-W190 HydrophobicContact CD2-CG 3.57Å; M186-W190 PolarHBondContact O-N 3.43Å; W187-W190 HydrophobicContact CE3-CB 4Å; W187-W190 HydrophobicContact CZ3-CB 4.07Å; W190-P192 WeakPolarHBondContact O-CD 3.15Å; W190-S250 VanDerWaalsContact CZ2-O 3.3Å; W190-S250 WeakPolarHBondContact CZ2-O 3.19Å; W190-S250 PolarHBondContact NE1-O 2.8Å; W190-D251 PolarHBondContact NE1-O 2.88Å; W190-P253 HydrophobicContact CD2-CG 3.94Å; W190-P253 HydrophobicContact CE3-CG 4.3Å; W190-P253 HydrophobicContact CG-CG 4.26Å; W190-P253 HydrophobicContact CZ2-CG 4.29Å; W190-H256 HydrophobicContact CH2-CB 3.8Å; W190-H256 AromaticContact CH2-CD2 3.36Å; W190-H256 WeakPolarHBondContact CH2-CD2 3.47Å; W190-H256 AromaticContact CH2-CG 3.63Å; W190-H256 HydrophobicContact CZ2-CB 4.17Å; W190-H256 AromaticContact CZ2-CD2 3.87Å; W190-I259 HydrophobicContact CZ3-CD1 4.34Å
191	A	84.7	Confident	82.1	Confident	0 Å²	0	45.9 Å²	45.9	0%	0	25%	0.246	C	C	.	.			trans	-100.5	114.5	-175.6	0	0	0	0	0	112	W187 R196 L199	W187-A191 HydrophobicContact CB-CB 4.29Å; W187-A191 HydrophobicContact CD2-CB 4.23Å; W187-A191 HydrophobicContact CE3-CB 3.46Å; W187-A191 VanDerWaalsContact CE3-CB 3.46Å; W187-A191 HydrophobicContact CZ3-CB 4.21Å; W187-A191 WeakPolarHBondContact O-CB 3.42Å; W187-A191 PolarHBondContact O-N 3.4Å; A191-R196 HydrophobicContact CB-CB 3.88Å; A191-R196 HydrophobicContact CB-CG 3.99Å; A191-L199 HydrophobicContact CB-CD1 3.89Å
192	P	83.3	Confident	82.3	Confident	0 Å²	0	46.8 Å²	46.8	0%	0	25%	0.25	C	C	.	.			trans	-57.1	146.3	166.1	-26.6	37.3	0	0	0	111.7	W190 L194 E195 R196 Y266 I267 S270	W190-P192 WeakPolarHBondContact O-CD 3.15Å; P192-L194 VanDerWaalsContact C-N 3.29Å; P192-L194 PolarHBondContact O-N 3.24Å; P192-L194 VanDerWaalsContact O-N 3.17Å; P192-E195 PolarHBondContact O-N 3.1Å; P192-E195 VanDerWaalsContact O-N 3.07Å; P192-R196 WeakPolarHBondContact O-CB 3.22Å; P192-R196 PolarHBondContact O-N 2.92Å; P192-Y266 HydrophobicContact CB-CE1 4.12Å; P192-Y266 HydrophobicContact CG-CD1 4.23Å; P192-Y266 HydrophobicContact CG-CE1 3.67Å; P192-I267 HydrophobicContact CG-CG1 4.32Å; P192-S270 WeakPolarHBondContact CB-OG 3.47Å
193	P	73.1	Confident	82.4	Confident	84 Å²	84	46.8 Å²	46.8	55%	0.545	25%	0.25	S	C	.	.	T	Hydrogen-bonded Turn	trans	-52.8	-41.7	-175.1	-28.5	34.8	0	0	0	114.6	E195 S270	P193-E195 VanDerWaalsContact C-N 3.31Å; P193-E195 PolarHBondContact O-N 3.38Å; P193-S270 WeakPolarHBondContact CD-O 3.25Å
194	L	73.1	Confident	82.2	Confident	159 Å²	159	48 Å²	48	83%	0.832	26%	0.263	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.9	-23.9	-177.3	-66.3	173.3	0	0	0	114.1	P192	P192-L194 VanDerWaalsContact C-N 3.29Å; P192-L194 PolarHBondContact O-N 3.24Å; P192-L194 VanDerWaalsContact O-N 3.17Å
195	E	79.4	Confident	82.2	Confident	16 Å²	16	47.7 Å²	47.7	8%	0.075	27%	0.266	C	S	.	.	T	Hydrogen-bonded Turn	trans	-114.1	-3.4	-176.3	-56.7	-167	148.5	0	0	112.6	R29 R34 P192 P193 S197 F198 L199	R29-E195 IonicContact CZ-OE1 2.72Å; R29-E195 IonicContact NE-OE1 3.69Å; R29-E195 PolarHBondContact NE-OE1 2.83Å; R29-E195 IonicContact NH2-OE1 3.61Å; R29-E195 PolarHBondContact NH2-OE1 3.34Å; R34-E195 IonicContact CZ-OE2 3.79Å; R34-E195 IonicContact NH1-OE2 2.88Å; R34-E195 PolarHBondContact NH1-OE2 3.48Å; R34-E195 IonicContact NH2-OE2 3.94Å; P192-E195 PolarHBondContact O-N 3.1Å; P192-E195 VanDerWaalsContact O-N 3.07Å; P193-E195 VanDerWaalsContact C-N 3.31Å; P193-E195 PolarHBondContact O-N 3.38Å; E195-S197 PolarHBondContact O-N 2.83Å; E195-F198 PolarHBondContact O-N 2.94Å; E195-L199 HydrophobicContact CB-CD1 4.33Å; E195-L199 WeakPolarHBondContact O-CG 3.24Å; E195-L199 PolarHBondContact O-N 3.32Å
196	R	79.6	Confident	82.5	Confident	90 Å²	90	47 Å²	47	34%	0.34	26%	0.261	S	S	.	.	H	α-helix	trans	-56.6	-49.2	-175.4	176.9	177.6	-88.6	178.6	-0.5	112.7	A191 P192 F198 L199 I200	A191-R196 HydrophobicContact CB-CB 3.88Å; A191-R196 HydrophobicContact CB-CG 3.99Å; P192-R196 WeakPolarHBondContact O-CB 3.22Å; P192-R196 PolarHBondContact O-N 2.92Å; R196-F198 VanDerWaalsContact C-N 3.26Å; R196-F198 PolarHBondContact O-N 3.5Å; R196-L199 PolarHBondContact O-N 3.42Å; R196-I200 HydrophobicContact CG-CD1 3.51Å; R196-I200 HydrophobicContact CG-CG1 4.25Å; R196-I200 WeakPolarHBondContact O-CB 3.49Å; R196-I200 WeakPolarHBondContact O-CG1 2.95Å; R196-I200 PolarHBondContact O-N 3.45Å
197	S	76.4	Confident	82.5	Confident	90 Å²	90	47 Å²	47	63%	0.629	26%	0.261	S	S	*	.	H	α-helix	trans	-62.5	-35.2	-178	-54.8	0	0	0	0	112.3	E195 S201	E195-S197 PolarHBondContact O-N 2.83Å; S197-S201 WeakPolarHBondContact O-CB 3.47Å; S197-S201 PolarHBondContact O-N 3.28Å; S197-S201 PolarHBondContact O-OG 3.39Å
198	F	83	Confident	82.3	Confident	130 Å²	130	50 Å²	50	57%	0.57	28%	0.282	S	S	*	.	H	α-helix	trans	-68.2	-48.5	175.7	172.9	-101.2	0	0	0	111.4	E195 R196 I200 S201 L202	E195-F198 PolarHBondContact O-N 2.94Å; R196-F198 VanDerWaalsContact C-N 3.26Å; R196-F198 PolarHBondContact O-N 3.5Å; F198-I200 PolarHBondContact O-N 2.98Å; F198-S201 PolarHBondContact O-N 3.18Å; F198-L202 HydrophobicContact CE1-CD2 4.2Å; F198-L202 HydrophobicContact CZ-CD2 4.23Å; F198-L202 VanDerWaalsContact O-CB 3.32Å; F198-L202 WeakPolarHBondContact O-CB 3.47Å; F198-L202 PolarHBondContact O-N 3.29Å
199	L	85.3	Confident	82.7	Confident	6 Å²	6	51.5 Å²	51.5	3%	0.031	28%	0.283	C	S	.	.	H	α-helix	trans	-64.6	-40.6	-178.4	-68.1	166.9	0	0	0	112.4	A38 W187 A191 E195 R196 S203	A38-L199 HydrophobicContact CB-CD2 3.89Å; W187-L199 HydrophobicContact CD2-CB 4.26Å; W187-L199 HydrophobicContact CE3-CB 4.02Å; W187-L199 HydrophobicContact CE3-CD1 4.23Å; W187-L199 HydrophobicContact CH2-CB 3.74Å; W187-L199 HydrophobicContact CH2-CD1 4.26Å; W187-L199 HydrophobicContact CH2-CD2 3.96Å; W187-L199 HydrophobicContact CH2-CG 4.19Å; W187-L199 HydrophobicContact CZ2-CB 3.97Å; W187-L199 HydrophobicContact CZ3-CB 3.76Å; W187-L199 HydrophobicContact CZ3-CD1 3.7Å; W187-L199 HydrophobicContact CZ3-CD2 4.24Å; W187-L199 HydrophobicContact CZ3-CG 4.1Å; A191-L199 HydrophobicContact CB-CD1 3.89Å; E195-L199 HydrophobicContact CB-CD1 4.33Å; E195-L199 WeakPolarHBondContact O-CG 3.24Å; E195-L199 PolarHBondContact O-N 3.32Å; R196-L199 PolarHBondContact O-N 3.42Å; L199-S203 WeakPolarHBondContact O-CB 3.44Å; L199-S203 PolarHBondContact O-N 3.22Å; L199-S203 PolarHBondContact O-OG 2.89Å
200	I	83.8	Confident	83.1	Confident	42 Å²	42	47.4 Å²	47.4	22%	0.215	27%	0.269	C	S	.	.	H	α-helix	trans	-65.1	-47.3	174.6	-68.3	173.7	0	0	0	110.5	M184 W187 R196 F198 L202 S203 G204	M184-I200 HydrophobicContact CE-CG2 3.77Å; M184-I200 HydrophobicContact SD-CD1 4.21Å; M184-I200 HydrophobicContact SD-CG1 4.44Å; M184-I200 HydrophobicContact SD-CG2 4.04Å; W187-I200 HydrophobicContact CB-CD1 4.38Å; W187-I200 HydrophobicContact CB-CG1 4.06Å; W187-I200 HydrophobicContact CG-CG1 3.84Å; R196-I200 HydrophobicContact CG-CD1 3.51Å; R196-I200 HydrophobicContact CG-CG1 4.25Å; R196-I200 WeakPolarHBondContact O-CB 3.49Å; R196-I200 WeakPolarHBondContact O-CG1 2.95Å; R196-I200 PolarHBondContact O-N 3.45Å; F198-I200 PolarHBondContact O-N 2.98Å; I200-L202 PolarHBondContact O-N 3.16Å; I200-S203 PolarHBondContact O-N 3.41Å; I200-G204 PolarHBondContact O-N 3.35Å
201	S	82.6	Confident	83.1	Confident	79 Å²	79	47.6 Å²	47.6	55%	0.552	27%	0.271	S	S	*	.	H	α-helix	trans	-62.6	-43	178.8	-62.4	0	0	0	0	112.2	S197 F198 G204 S205	S197-S201 WeakPolarHBondContact O-CB 3.47Å; S197-S201 PolarHBondContact O-N 3.28Å; S197-S201 PolarHBondContact O-OG 3.39Å; F198-S201 PolarHBondContact O-N 3.18Å; S201-G204 PolarHBondContact O-N 3.17Å; S201-S205 WeakPolarHBondContact O-CB 3.48Å; S201-S205 PolarHBondContact O-N 3.46Å; S201-S205 PolarHBondContact O-OG 3.2Å
202	L	87.3	Confident	83.1	Confident	46 Å²	46	49.3 Å²	49.3	24%	0.241	28%	0.282	C	S	.	.	H	α-helix	trans	-60.1	-49.2	175.8	179.5	59.3	0	0	0	110.1	L35 A38 F42 F198 I200 G204 S205	L35-L202 HydrophobicContact CD1-CD2 3.77Å; A38-L202 HydrophobicContact CB-CD2 3.86Å; A38-L202 HydrophobicContact CB-CG 4.34Å; F42-L202 VanDerWaalsContact CD2-O 3.29Å; F42-L202 WeakPolarHBondContact CD2-O 3.33Å; F198-L202 HydrophobicContact CE1-CD2 4.2Å; F198-L202 HydrophobicContact CZ-CD2 4.23Å; F198-L202 VanDerWaalsContact O-CB 3.32Å; F198-L202 WeakPolarHBondContact O-CB 3.47Å; F198-L202 PolarHBondContact O-N 3.29Å; I200-L202 PolarHBondContact O-N 3.16Å; L202-G204 PolarHBondContact O-N 3.17Å; L202-S205 PolarHBondContact O-N 3.03Å; L202-S205 PolarHBondContact O-OG 3.06Å
203	S	88.5	Confident	83.3	Confident	0 Å²	0	53.9 Å²	53.9	0%	0	31%	0.306	C	S	.	.	H	α-helix	trans	-62.9	-44.6	179.2	-53.2	0	0	0	0	112.4	W187 L199 I200 G206	W187-S203 WeakPolarHBondContact CZ2-OG 3.35Å; W187-S203 PolarHBondContact NE1-OG 3.06Å; L199-S203 WeakPolarHBondContact O-CB 3.44Å; L199-S203 PolarHBondContact O-N 3.22Å; L199-S203 PolarHBondContact O-OG 2.89Å; I200-S203 PolarHBondContact O-N 3.41Å; S203-G206 PolarHBondContact O-N 2.94Å
204	G	84.1	Confident	84.1	Confident	27 Å²	27	50.2 Å²	50.2	28%	0.278	28%	0.283	S	S	.	.	H	α-helix	trans	-69.7	-31.6	-178.2	0	0	0	0	0	113.9	I200 S201 L202 G206 G207	I200-G204 PolarHBondContact O-N 3.35Å; S201-G204 PolarHBondContact O-N 3.17Å; L202-G204 PolarHBondContact O-N 3.17Å; G204-G206 PolarHBondContact O-N 3.02Å; G204-G207 PolarHBondContact O-N 3.23Å; G204-G207 VanDerWaalsContact O-N 3.08Å
205	S	83.9	Confident	84.8	Confident	53 Å²	53	42.8 Å²	42.8	37%	0.371	24%	0.244	S	C	.	.	H	α-helix	trans	-61	-17.4	176.6	68.2	0	0	0	0	113.5	F42 S201 L202 G207 S208 F209	F42-S205 WeakPolarHBondContact CD2-OG 3.49Å; F42-S205 WeakPolarHBondContact CE2-OG 3.44Å; S201-S205 WeakPolarHBondContact O-CB 3.48Å; S201-S205 PolarHBondContact O-N 3.46Å; S201-S205 PolarHBondContact O-OG 3.2Å; L202-S205 PolarHBondContact O-N 3.03Å; L202-S205 PolarHBondContact O-OG 3.06Å; S205-G207 PolarHBondContact O-N 3.45Å; S205-S208 PolarHBondContact O-N 3.42Å; S205-F209 PolarHBondContact O-N 3.17Å; S205-F209 VanDerWaalsContact O-N 3.17Å
206	G	87.4	Confident	85.3	Confident	0 Å²	0	43.7 Å²	43.7	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-54.6	-33	172	0	0	0	0	0	113	F42 S46 S203 G204 F209 G210	F42-G206 VanDerWaalsContact CE2-CA 3.42Å; F42-G206 WeakPolarHBondContact O-CA 3.44Å; S46-G206 WeakPolarHBondContact CA-O 3.26Å; S46-G206 WeakPolarHBondContact CB-O 3.42Å; S46-G206 PolarHBondContact N-O 3.42Å; S46-G206 VanDerWaalsContact OG-CA 3.28Å; S46-G206 WeakPolarHBondContact OG-CA 3.4Å; S46-G206 PolarHBondContact OG-O 3.02Å; S203-G206 PolarHBondContact O-N 2.94Å; G204-G206 PolarHBondContact O-N 3.02Å; G206-F209 PolarHBondContact O-N 2.97Å; G206-G210 PolarHBondContact O-N 3.18Å
207	G	86	Confident	85.8	Confident	2 Å²	2	43.1 Å²	43.1	2%	0.021	26%	0.255	C	S	.	.	H	α-helix	trans	-66.7	-47.7	-178.3	0	0	0	0	0	112.6	Y49 G204 S205 G210 A211	Y49-G207 WeakPolarHBondContact CB-O 3.4Å; Y49-G207 WeakPolarHBondContact CD1-O 3.39Å; G204-G207 PolarHBondContact O-N 3.23Å; G204-G207 VanDerWaalsContact O-N 3.08Å; S205-G207 PolarHBondContact O-N 3.45Å; G207-G210 PolarHBondContact O-N 3.24Å; G207-A211 PolarHBondContact O-N 3.08Å
208	S	82.8	Confident	86.5	Confident	64 Å²	64	38.9 Å²	38.9	45%	0.448	23%	0.225	S	C	.	.	H	α-helix	trans	-64.4	-41.1	176	-54.2	0	0	0	0	111.8	S205 C212	S205-S208 PolarHBondContact O-N 3.42Å; S208-C212 VanDerWaalsContact O-CB 3.28Å; S208-C212 WeakPolarHBondContact O-CB 3.49Å; S208-C212 PolarHBondContact O-N 3.43Å
209	F	86.3	Confident	86.7	Confident	102 Å²	102	32.7 Å²	32.7	45%	0.447	20%	0.198	S	C	.	.	H	α-helix	trans	-62.4	-44.5	175.5	-179.4	-99.6	0	0	0	111.8	F42 S205 G206 C212 L213	F42-F209 AromaticContact CE1-CD1 3.86Å; F42-F209 HydrophobicContact CE1-CD1 3.86Å; F42-F209 HydrophobicContact CE1-CE1 4.25Å; F42-F209 HydrophobicContact CE1-CG 4.26Å; F42-F209 HydrophobicContact CE2-CB 4.02Å; F42-F209 HydrophobicContact CE2-CG 4.4Å; F42-F209 HydrophobicContact CZ-CB 3.67Å; F42-F209 AromaticContact CZ-CD1 3.63Å; F42-F209 HydrophobicContact CZ-CD1 3.63Å; F42-F209 HydrophobicContact CZ-CD2 4.21Å; F42-F209 HydrophobicContact CZ-CE1 4.33Å; F42-F209 AromaticContact CZ-CG 3.56Å; F42-F209 HydrophobicContact CZ-CG 3.56Å; S205-F209 PolarHBondContact O-N 3.17Å; S205-F209 VanDerWaalsContact O-N 3.17Å; G206-F209 PolarHBondContact O-N 2.97Å; F209-C212 PolarHBondContact O-N 2.87Å; F209-L213 HydrophobicContact CE1-CD2 4.24Å; F209-L213 HydrophobicContact CZ-CD2 4.46Å; F209-L213 WeakPolarHBondContact O-CB 3.21Å; F209-L213 PolarHBondContact O-N 3.31Å
210	G	89.1	Confident	86.9	Confident	4 Å²	4	37.9 Å²	37.9	4%	0.041	22%	0.218	C	C	.	.	H	α-helix	trans	-59.5	-49.4	177.4	0	0	0	0	0	112.4	S46 G206 G207 C212 L213 A214	S46-G210 WeakPolarHBondContact O-CA 3.38Å; G206-G210 PolarHBondContact O-N 3.18Å; G207-G210 PolarHBondContact O-N 3.24Å; G210-C212 PolarHBondContact O-N 2.92Å; G210-L213 PolarHBondContact O-N 2.85Å; G210-A214 WeakPolarHBondContact O-CB 3.45Å; G210-A214 PolarHBondContact O-N 3.47Å
211	A	84.8	Confident	87.2	Confident	6 Å²	6	36.5 Å²	36.5	5%	0.05	21%	0.211	C	C	.	.	H	α-helix	trans	-61.6	-43.4	176.8	0	0	0	0	0	112.2	Y49 V53 G207 L213 A214 L215	Y49-A211 HydrophobicContact CD1-CB 4.39Å; V53-A211 HydrophobicContact CG1-CB 4.39Å; G207-A211 PolarHBondContact O-N 3.08Å; A211-L213 VanDerWaalsContact C-N 3.3Å; A211-L213 PolarHBondContact O-N 3.13Å; A211-A214 PolarHBondContact O-N 2.91Å; A211-L215 WeakPolarHBondContact O-CG 3.45Å; A211-L215 PolarHBondContact O-N 3.26Å
212	C	84.5	Confident	87.4	Confident	35 Å²	35	32.8 Å²	32.8	24%	0.236	18%	0.184	C	C	.	.	H	α-helix	trans	-61.6	-37.2	178.4	-175.4	0	0	0	0	112.7	S208 F209 G210 P216	S208-C212 VanDerWaalsContact O-CB 3.28Å; S208-C212 WeakPolarHBondContact O-CB 3.49Å; S208-C212 PolarHBondContact O-N 3.43Å; F209-C212 PolarHBondContact O-N 2.87Å; G210-C212 PolarHBondContact O-N 2.92Å; C212-P216 WeakPolarHBondContact O-CD 3.46Å; C212-P216 WeakPolarHBondContact O-CG 3.04Å
213	L	88.7	Confident	87.2	Confident	97 Å²	97	32.2 Å²	32.2	51%	0.508	18%	0.181	S	C	.	.	H	α-helix	trans	-82.5	-38.7	179.3	-175.9	62.7	0	0	0	112.1	F209 G210 A211 P216 L217	F209-L213 HydrophobicContact CE1-CD2 4.24Å; F209-L213 HydrophobicContact CZ-CD2 4.46Å; F209-L213 WeakPolarHBondContact O-CB 3.21Å; F209-L213 PolarHBondContact O-N 3.31Å; G210-L213 PolarHBondContact O-N 2.85Å; A211-L213 VanDerWaalsContact C-N 3.3Å; A211-L213 PolarHBondContact O-N 3.13Å; L213-P216 WeakPolarHBondContact O-CD 3.38Å; L213-L217 WeakPolarHBondContact O-CB 3.37Å; L213-L217 PolarHBondContact O-N 3Å
214	A	90	Very high	87.2	Confident	7 Å²	7	37.1 Å²	37.1	6%	0.058	20%	0.203	C	C	.	.	H	α-helix	trans	-72.5	-37.3	-172.6	0	0	0	0	0	113.2	G50 V53 G210 A211 T218	G50-A214 VanDerWaalsContact CA-CB 3.49Å; V53-A214 HydrophobicContact CG2-CB 3.54Å; G210-A214 WeakPolarHBondContact O-CB 3.45Å; G210-A214 PolarHBondContact O-N 3.47Å; A211-A214 PolarHBondContact O-N 2.91Å; A214-T218 WeakPolarHBondContact O-CB 3.29Å; A214-T218 PolarHBondContact O-N 3.41Å; A214-T218 PolarHBondContact O-OG1 3.18Å
215	L	88.3	Confident	87.3	Confident	2 Å²	2	41.1 Å²	41.1	1%	0.01	22%	0.218	C	C	.	.	H	α-helix	trans	-62.2	-51.9	-179.1	-70.2	168.9	0	0	0	112.5	V53 V57 A211 T218 G219 G330 A334 Y337	V53-L215 HydrophobicContact CB-CD2 4.07Å; V53-L215 HydrophobicContact CB-CG 4.48Å; V53-L215 HydrophobicContact CG2-CD2 4.17Å; V53-L215 HydrophobicContact CG2-CG 4.19Å; V57-L215 HydrophobicContact CG2-CD2 3.52Å; A211-L215 WeakPolarHBondContact O-CG 3.45Å; A211-L215 PolarHBondContact O-N 3.26Å; L215-T218 PolarHBondContact O-N 3.34Å; L215-G219 PolarHBondContact O-N 3.22Å; L215-G330 CarbonylContact C-O 3.56Å; L215-A334 HydrophobicContact CB-CB 4.07Å; L215-A334 HydrophobicContact CD1-CB 4.33Å; L215-Y337 HydrophobicContact CD1-CD2 3.93Å; L215-Y337 HydrophobicContact CD1-CE2 4.08Å
216	P	89.1	Confident	87.5	Confident	35 Å²	35	38.6 Å²	38.6	23%	0.227	20%	0.2	C	C	.	.	H	α-helix	trans	-68.4	-38.8	177.4	-18.3	33	0	0	0	112.5	C212 L213 T218 G219 Y220 A334	C212-P216 WeakPolarHBondContact O-CD 3.46Å; C212-P216 WeakPolarHBondContact O-CG 3.04Å; L213-P216 WeakPolarHBondContact O-CD 3.38Å; P216-T218 VanDerWaalsContact C-N 3.31Å; P216-T218 PolarHBondContact O-N 3.02Å; P216-G219 PolarHBondContact O-N 3.07Å; P216-Y220 PolarHBondContact O-N 3.3Å; P216-A334 HydrophobicContact CG-CB 3.67Å
217	L	90.6	Very high	87.7	Confident	79 Å²	79	38.6 Å²	38.6	41%	0.414	20%	0.2	S	C	.	.	H	α-helix	trans	-63.1	-39.9	179.3	-175.9	63	0	0	0	111.3	L213 Y220 I221	L213-L217 WeakPolarHBondContact O-CB 3.37Å; L213-L217 PolarHBondContact O-N 3Å; L217-Y220 PolarHBondContact O-N 3.29Å; L217-I221 HydrophobicContact CD1-CD1 3.89Å; L217-I221 HydrophobicContact CD1-CG1 4.25Å; L217-I221 HydrophobicContact CD2-CD1 4.37Å; L217-I221 HydrophobicContact CG-CD1 3.67Å; L217-I221 HydrophobicContact CG-CG1 4.42Å; L217-I221 WeakPolarHBondContact O-CB 3.32Å; L217-I221 WeakPolarHBondContact O-CD1 3.4Å; L217-I221 WeakPolarHBondContact O-CG1 3.2Å; L217-I221 PolarHBondContact O-N 3.17Å
218	T	90.4	Very high	88	Confident	1 Å²	1	39.9 Å²	39.9	1%	0.006	21%	0.208	C	C	.	.	H	α-helix	trans	-62.7	-47.7	175.2	-61.6	0	0	0	0	111.1	V57 A214 L215 P216 Y220 I221 C222 V230	V57-T218 HydrophobicContact CB-CG2 3.67Å; V57-T218 HydrophobicContact CG1-CG2 3.8Å; A214-T218 WeakPolarHBondContact O-CB 3.29Å; A214-T218 PolarHBondContact O-N 3.41Å; A214-T218 PolarHBondContact O-OG1 3.18Å; L215-T218 PolarHBondContact O-N 3.34Å; P216-T218 VanDerWaalsContact C-N 3.31Å; P216-T218 PolarHBondContact O-N 3.02Å; T218-Y220 VanDerWaalsContact C-N 3.34Å; T218-Y220 PolarHBondContact O-N 2.9Å; T218-I221 PolarHBondContact O-N 3.25Å; T218-C222 WeakPolarHBondContact O-CB 3.46Å; T218-C222 PolarHBondContact O-N 3.37Å; T218-C222 PolarHBondContact O-SG 3.09Å; T218-V230 HydrophobicContact CG2-CB 4.48Å; T218-V230 HydrophobicContact CG2-CG1 3.71Å; T218-V230 HydrophobicContact CG2-CG2 4Å
219	G	87	Confident	88.5	Confident	0 Å²	0	37.7 Å²	37.7	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-57.7	-46.2	177.4	0	0	0	0	0	112.4	L215 P216 C222 E223	L215-G219 PolarHBondContact O-N 3.22Å; P216-G219 PolarHBondContact O-N 3.07Å; G219-C222 PolarHBondContact O-N 3.5Å; G219-E223 PolarHBondContact O-N 3.26Å
220	Y	89.3	Confident	88.8	Confident	115 Å²	115	32.8 Å²	32.8	45%	0.451	17%	0.173	S	C	.	.	H	α-helix	trans	-63.9	-46.2	178	179.9	-105.7	0	0	0	113.2	P216 L217 T218 E223 Q224	P216-Y220 PolarHBondContact O-N 3.3Å; L217-Y220 PolarHBondContact O-N 3.29Å; T218-Y220 VanDerWaalsContact C-N 3.34Å; T218-Y220 PolarHBondContact O-N 2.9Å; Y220-E223 PolarHBondContact O-N 3.34Å; Y220-Q224 HydrophobicContact CD2-CG 4.3Å; Y220-Q224 HydrophobicContact CE1-CG 4.39Å; Y220-Q224 HydrophobicContact CE2-CG 3.9Å; Y220-Q224 WeakPolarHBondContact O-CG 3.36Å; Y220-Q224 PolarHBondContact O-N 2.84Å
221	I	90.1	Very high	89.1	Confident	13 Å²	13	32.6 Å²	32.6	7%	0.067	17%	0.171	C	C	.	.	H	α-helix	trans	-65.1	-42.2	179.5	-69.3	165.6	0	0	0	110.6	L217 T218 E223 Q224 L225 G226 A229 V230 L233	L217-I221 HydrophobicContact CD1-CD1 3.89Å; L217-I221 HydrophobicContact CD1-CG1 4.25Å; L217-I221 HydrophobicContact CD2-CD1 4.37Å; L217-I221 HydrophobicContact CG-CD1 3.67Å; L217-I221 HydrophobicContact CG-CG1 4.42Å; L217-I221 WeakPolarHBondContact O-CB 3.32Å; L217-I221 WeakPolarHBondContact O-CD1 3.4Å; L217-I221 WeakPolarHBondContact O-CG1 3.2Å; L217-I221 PolarHBondContact O-N 3.17Å; T218-I221 PolarHBondContact O-N 3.25Å; I221-E223 VanDerWaalsContact C-N 3.26Å; I221-E223 PolarHBondContact O-N 3.17Å; I221-Q224 PolarHBondContact O-N 3.42Å; I221-L225 HydrophobicContact CG2-CB 4.29Å; I221-L225 HydrophobicContact CG2-CD1 4.38Å; I221-L225 WeakPolarHBondContact O-CA 3.36Å; I221-L225 PolarHBondContact O-N 2.94Å; I221-G226 PolarHBondContact O-N 2.97Å; I221-A229 HydrophobicContact CG2-CB 3.77Å; I221-V230 HydrophobicContact CB-CG2 3.92Å; I221-V230 HydrophobicContact CG2-CB 4.4Å; I221-V230 HydrophobicContact CG2-CG2 3.57Å; I221-L233 HydrophobicContact CD1-CD1 3.74Å; I221-L233 HydrophobicContact CG1-CD1 4.26Å; I221-L233 HydrophobicContact CG2-CD1 4.18Å
222	C	87.6	Confident	89.5	Confident	0 Å²	0	38 Å²	38	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-60.1	-37.4	179.7	-77.4	0	0	0	0	112.6	A61 T218 G219 G226 V230 L326	A61-C222 HydrophobicContact CB-CB 4.33Å; T218-C222 WeakPolarHBondContact O-CB 3.46Å; T218-C222 PolarHBondContact O-N 3.37Å; T218-C222 PolarHBondContact O-SG 3.09Å; G219-C222 PolarHBondContact O-N 3.5Å; C222-G226 VanDerWaalsContact O-CA 3.22Å; C222-G226 WeakPolarHBondContact O-CA 3.47Å; C222-G226 PolarHBondContact O-N 2.92Å; C222-V230 WeakPolarHBondContact SG-CG2 3.32Å; C222-L326 HydrophobicContact CB-CD2 3.21Å; C222-L326 HydrophobicContact CB-CG 4.22Å
223	E	83.6	Confident	90	Very high	34 Å²	34	40.7 Å²	40.7	16%	0.159	20%	0.202	C	C	.	.	H	α-helix	trans	-72.3	-42	179.4	-167.5	-178.9	134.7	0	0	112.1	Q94 G219 Y220 I221 Q327	Q94-E223 HydrophobicContact CB-CG 4.09Å; Q94-E223 VanDerWaalsContact O-CA 3.32Å; Q94-E223 WeakPolarHBondContact O-CA 3.46Å; Q94-E223 VanDerWaalsContact O-CG 3.3Å; Q94-E223 WeakPolarHBondContact O-CG 3.46Å; G219-E223 PolarHBondContact O-N 3.26Å; Y220-E223 PolarHBondContact O-N 3.34Å; I221-E223 VanDerWaalsContact C-N 3.26Å; I221-E223 PolarHBondContact O-N 3.17Å; E223-Q327 WeakPolarHBondContact OE2-CB 3.21Å
224	Q	87.3	Confident	90.2	Very high	103 Å²	103	37 Å²	37	48%	0.481	18%	0.184	S	C	.	.	H	α-helix	trans	-86.8	-38.6	-173	-63.2	-64.1	-32.3	0	0	114	Y220 I221	Y220-Q224 HydrophobicContact CD2-CG 4.3Å; Y220-Q224 HydrophobicContact CE1-CG 4.39Å; Y220-Q224 HydrophobicContact CE2-CG 3.9Å; Y220-Q224 WeakPolarHBondContact O-CG 3.36Å; Y220-Q224 PolarHBondContact O-N 2.84Å; I221-Q224 PolarHBondContact O-N 3.42Å
225	L	86.6	Confident	90.3	Very high	111 Å²	111	36.7 Å²	36.7	58%	0.581	18%	0.182	S	C	*	.	H	α-helix	trans	-121	-3.7	-170.2	-61.5	174.1	0	0	0	113	I221 A229 L233	I221-L225 HydrophobicContact CG2-CB 4.29Å; I221-L225 HydrophobicContact CG2-CD1 4.38Å; I221-L225 WeakPolarHBondContact O-CA 3.36Å; I221-L225 PolarHBondContact O-N 2.94Å; L225-A229 HydrophobicContact CB-CB 3.61Å; L225-A229 HydrophobicContact CD1-CB 4.38Å; L225-L233 HydrophobicContact CD1-CD1 4.46Å
226	G	88.6	Confident	90.7	Very high	0 Å²	0	38.2 Å²	38.2	0%	0	20%	0.198	C	C	.	.			trans	82.5	160.8	-173.5	0	0	0	0	0	112.9	I221 C222 A229	I221-G226 PolarHBondContact O-N 2.97Å; C222-G226 VanDerWaalsContact O-CA 3.22Å; C222-G226 WeakPolarHBondContact O-CA 3.47Å; C222-G226 PolarHBondContact O-N 2.92Å; G226-A229 PolarHBondContact O-N 3.36Å
227	W	90.9	Very high	90.9	Very high	1 Å²	1	38.8 Å²	38.8	0%	0.004	21%	0.205	C	C	.	.	H	α-helix	trans	-61.3	-31.9	-178.2	69.7	-102.1	0	0	0	115.2	A61 M62 T99 P100 Y102 P155 A158 A229 V230 F231	A61-W227 HydrophobicContact CB-CB 4.22Å; M62-W227 HydrophobicContact CE-CD2 4.46Å; M62-W227 HydrophobicContact CE-CE3 4.1Å; M62-W227 HydrophobicContact CE-CH2 3.86Å; M62-W227 HydrophobicContact CE-CZ2 4.22Å; M62-W227 HydrophobicContact CE-CZ3 3.77Å; M62-W227 HydrophobicContact CG-CB 4.26Å; M62-W227 HydrophobicContact CG-CD2 3.51Å; M62-W227 HydrophobicContact CG-CE3 3.89Å; M62-W227 HydrophobicContact CG-CG 3.67Å; M62-W227 HydrophobicContact CG-CZ2 4.37Å; M62-W227 HydrophobicContact CG-CZ3 4.46Å; M62-W227 HydrophobicContact SD-CD2 4.25Å; M62-W227 HydrophobicContact SD-CE3 4Å; M62-W227 HydrophobicContact SD-CZ3 4.27Å; T99-W227 HydrophobicContact CG2-CG 4.29Å; P100-W227 HydrophobicContact CG-CZ2 3.81Å; P100-W227 PolarHBondContact O-NE1 3.22Å; Y102-W227 HydrophobicContact CE2-CH2 4.13Å; Y102-W227 AromaticContact CE2-CZ2 3.62Å; Y102-W227 HydrophobicContact CE2-CZ2 3.62Å; P155-W227 HydrophobicContact CB-CH2 3.99Å; P155-W227 HydrophobicContact CB-CZ3 3.79Å; P155-W227 HydrophobicContact CG-CZ3 4.07Å; A158-W227 HydrophobicContact CB-CH2 3.8Å; A158-W227 HydrophobicContact CB-CZ3 4.46Å; W227-A229 PolarHBondContact O-N 3.11Å; W227-V230 WeakPolarHBondContact O-CB 3.33Å; W227-V230 PolarHBondContact O-N 3.37Å; W227-F231 AromaticContact CE3-CD2 3.7Å; W227-F231 HydrophobicContact CE3-CD2 3.7Å; W227-F231 AromaticContact CE3-CE2 3.5Å; W227-F231 HydrophobicContact CE3-CE2 3.5Å; W227-F231 VanDerWaalsContact CE3-CE2 3.5Å; W227-F231 AromaticContact CZ3-CD2 3.85Å; W227-F231 HydrophobicContact CZ3-CD2 3.85Å; W227-F231 AromaticContact CZ3-CE2 3.79Å; W227-F231 HydrophobicContact CZ3-CE2 3.79Å
228	P	92.9	Very high	91.1	Very high	28 Å²	28	35 Å²	35	18%	0.182	19%	0.185	C	C	.	.	H	α-helix	trans	-62.1	-32.8	-179.8	-25.4	37.1	0	0	0	112.7	P155 V230 F231 Y232	P155-P228 HydrophobicContact CB-CB 4.03Å; P155-P228 HydrophobicContact CG-CB 4.11Å; P228-V230 VanDerWaalsContact C-N 3.26Å; P228-V230 PolarHBondContact O-N 2.81Å; P228-F231 PolarHBondContact O-N 3.41Å; P228-Y232 HydrophobicContact CB-CE2 4.07Å; P228-Y232 VanDerWaalsContact O-CD2 3.27Å; P228-Y232 WeakPolarHBondContact O-CD2 3.49Å; P228-Y232 PolarHBondContact O-N 2.83Å
229	A	92.4	Very high	91.4	Very high	18 Å²	18	36.4 Å²	36.4	15%	0.149	20%	0.195	C	C	.	.	H	α-helix	trans	-62.5	-32.3	-178.6	0	0	0	0	0	112.6	I221 L225 G226 W227 F231 Y232 L233	I221-A229 HydrophobicContact CG2-CB 3.77Å; L225-A229 HydrophobicContact CB-CB 3.61Å; L225-A229 HydrophobicContact CD1-CB 4.38Å; G226-A229 PolarHBondContact O-N 3.36Å; W227-A229 PolarHBondContact O-N 3.11Å; A229-F231 VanDerWaalsContact C-N 3.33Å; A229-F231 PolarHBondContact O-N 3.44Å; A229-Y232 PolarHBondContact O-N 2.85Å; A229-L233 WeakPolarHBondContact O-CB 3.39Å; A229-L233 VanDerWaalsContact O-CG 3.27Å; A229-L233 WeakPolarHBondContact O-CG 3.44Å; A229-L233 PolarHBondContact O-N 2.96Å
230	V	93.1	Very high	91.8	Very high	0 Å²	0	41 Å²	41	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-58	-48.9	176.8	-179	0	0	0	0	110.4	N54 T218 I221 C222 W227 P228 Y232 L233 C234	N54-V230 HydrophobicContact CB-CG1 3.79Å; T218-V230 HydrophobicContact CG2-CB 4.48Å; T218-V230 HydrophobicContact CG2-CG1 3.71Å; T218-V230 HydrophobicContact CG2-CG2 4Å; I221-V230 HydrophobicContact CB-CG2 3.92Å; I221-V230 HydrophobicContact CG2-CB 4.4Å; I221-V230 HydrophobicContact CG2-CG2 3.57Å; C222-V230 WeakPolarHBondContact SG-CG2 3.32Å; W227-V230 WeakPolarHBondContact O-CB 3.33Å; W227-V230 PolarHBondContact O-N 3.37Å; P228-V230 VanDerWaalsContact C-N 3.26Å; P228-V230 PolarHBondContact O-N 2.81Å; V230-Y232 PolarHBondContact O-N 3.45Å; V230-L233 PolarHBondContact O-N 2.86Å; V230-C234 VanDerWaalsContact O-CB 3.3Å; V230-C234 WeakPolarHBondContact O-CB 3.34Å; V230-C234 PolarHBondContact O-N 3.48Å; V230-C234 PolarHBondContact O-SG 3.42Å; V230-C234 VanDerWaalsContact O-SG 3.33Å
231	F	94.4	Very high	92.1	Very high	0 Å²	0	36.1 Å²	36.1	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-67.5	-38.5	-177.2	-64.2	-61.3	0	0	0	111.9	N54 L55 A58 M62 T151 T154 P155 W227 P228 A229 G235	N54-F231 HydrophobicContact CB-CE1 4.38Å; N54-F231 WeakPolarHBondContact OD1-CE1 3.33Å; L55-F231 HydrophobicContact CD1-CE1 4.49Å; L55-F231 HydrophobicContact CD1-CZ 3.86Å; A58-F231 HydrophobicContact CB-CE2 4.08Å; A58-F231 HydrophobicContact CB-CZ 3.81Å; M62-F231 HydrophobicContact SD-CE2 4.08Å; M62-F231 HydrophobicContact SD-CZ 4.32Å; T151-F231 HydrophobicContact CG2-CB 4.2Å; T151-F231 HydrophobicContact CG2-CD1 3.79Å; T151-F231 HydrophobicContact CG2-CG 4.49Å; T151-F231 WeakPolarHBondContact O-CB 3.45Å; T154-F231 HydrophobicContact CG2-CD1 3.85Å; T154-F231 HydrophobicContact CG2-CD2 3.75Å; T154-F231 HydrophobicContact CG2-CE1 3.85Å; T154-F231 HydrophobicContact CG2-CE2 3.7Å; T154-F231 HydrophobicContact CG2-CG 3.81Å; T154-F231 HydrophobicContact CG2-CZ 3.76Å; P155-F231 HydrophobicContact CG-CB 3.86Å; P155-F231 HydrophobicContact CG-CD2 4.03Å; P155-F231 HydrophobicContact CG-CG 4.33Å; W227-F231 AromaticContact CE3-CD2 3.7Å; W227-F231 HydrophobicContact CE3-CD2 3.7Å; W227-F231 AromaticContact CE3-CE2 3.5Å; W227-F231 HydrophobicContact CE3-CE2 3.5Å; W227-F231 VanDerWaalsContact CE3-CE2 3.5Å; W227-F231 AromaticContact CZ3-CD2 3.85Å; W227-F231 HydrophobicContact CZ3-CD2 3.85Å; W227-F231 AromaticContact CZ3-CE2 3.79Å; W227-F231 HydrophobicContact CZ3-CE2 3.79Å; P228-F231 PolarHBondContact O-N 3.41Å; A229-F231 VanDerWaalsContact C-N 3.33Å; A229-F231 PolarHBondContact O-N 3.44Å; F231-G235 WeakPolarHBondContact O-CA 3.41Å; F231-G235 PolarHBondContact O-N 3.13Å
232	Y	94.8	Very high	92.4	Very high	119 Å²	119	37 Å²	37	47%	0.467	20%	0.203	S	C	.	.	H	α-helix	trans	-66.8	-43.3	174.9	-61.9	-42.4	0	0	0	113	V152 P155 P228 A229 V230 G236	V152-Y232 HydrophobicContact CG1-CD1 4.01Å; V152-Y232 HydrophobicContact CG1-CE1 4.29Å; V152-Y232 VanDerWaalsContact O-CE1 3.25Å; V152-Y232 WeakPolarHBondContact O-CE1 3.14Å; P155-Y232 HydrophobicContact CG-CE1 3.99Å; P155-Y232 HydrophobicContact CG-CE2 4.38Å; P228-Y232 HydrophobicContact CB-CE2 4.07Å; P228-Y232 VanDerWaalsContact O-CD2 3.27Å; P228-Y232 WeakPolarHBondContact O-CD2 3.49Å; P228-Y232 PolarHBondContact O-N 2.83Å; A229-Y232 PolarHBondContact O-N 2.85Å; V230-Y232 PolarHBondContact O-N 3.45Å; Y232-G236 WeakPolarHBondContact O-CA 3.41Å; Y232-G236 PolarHBondContact O-N 3.21Å
233	L	94.1	Very high	92.8	Very high	92 Å²	92	41.4 Å²	41.4	48%	0.482	23%	0.226	S	C	.	.	H	α-helix	trans	-71	-47.2	-179	-70.5	172.2	0	0	0	111.7	I221 L225 A229 V230 G236 A237	I221-L233 HydrophobicContact CD1-CD1 3.74Å; I221-L233 HydrophobicContact CG1-CD1 4.26Å; I221-L233 HydrophobicContact CG2-CD1 4.18Å; L225-L233 HydrophobicContact CD1-CD1 4.46Å; A229-L233 WeakPolarHBondContact O-CB 3.39Å; A229-L233 VanDerWaalsContact O-CG 3.27Å; A229-L233 WeakPolarHBondContact O-CG 3.44Å; A229-L233 PolarHBondContact O-N 2.96Å; V230-L233 PolarHBondContact O-N 2.86Å; L233-G236 PolarHBondContact O-N 2.85Å; L233-A237 WeakPolarHBondContact O-CB 3.08Å; L233-A237 PolarHBondContact O-N 3.2Å
234	C	92.4	Very high	93.2	Very high	20 Å²	20	44.7 Å²	44.7	14%	0.135	24%	0.24	C	C	.	.	H	α-helix	trans	-66.2	-45.1	177.8	-66.2	0	0	0	0	111.7	L51 V230 A237 G238	L51-C234 HydrophobicContact CD2-CB 3.9Å; V230-C234 VanDerWaalsContact O-CB 3.3Å; V230-C234 WeakPolarHBondContact O-CB 3.34Å; V230-C234 PolarHBondContact O-N 3.48Å; V230-C234 PolarHBondContact O-SG 3.42Å; V230-C234 VanDerWaalsContact O-SG 3.33Å; C234-A237 PolarHBondContact O-N 2.88Å; C234-G238 PolarHBondContact O-N 3.01Å; C234-G238 VanDerWaalsContact O-N 3.11Å
235	G	93.6	Very high	93.6	Very high	0 Å²	0	39.8 Å²	39.8	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-63.7	-41.8	175.9	0	0	0	0	0	112.3	F231 A237 G238 C239	F231-G235 WeakPolarHBondContact O-CA 3.41Å; F231-G235 PolarHBondContact O-N 3.13Å; G235-A237 VanDerWaalsContact C-N 3.35Å; G235-A237 PolarHBondContact O-N 2.71Å; G235-G238 PolarHBondContact O-N 3.34Å; G235-C239 PolarHBondContact O-N 2.84Å; G235-C239 PolarHBondContact O-SG 3.32Å
236	G	94.9	Very high	93.8	Very high	34 Å²	34	37.2 Å²	37.2	35%	0.351	21%	0.207	S	C	.	.	H	α-helix	trans	-59.9	-41.7	173.7	0	0	0	0	0	113.1	Y232 L233 G238 C239 L240	Y232-G236 WeakPolarHBondContact O-CA 3.41Å; Y232-G236 PolarHBondContact O-N 3.21Å; L233-G236 PolarHBondContact O-N 2.85Å; G236-G238 VanDerWaalsContact C-N 3.33Å; G236-G238 PolarHBondContact O-N 3.38Å; G236-C239 PolarHBondContact O-N 3.47Å; G236-L240 WeakPolarHBondContact O-CB 3.22Å; G236-L240 PolarHBondContact O-N 3Å
237	A	94.4	Very high	93.9	Very high	46 Å²	46	42.4 Å²	42.4	38%	0.38	23%	0.234	S	C	.	.	H	α-helix	trans	-62.1	-38.2	174.8	0	0	0	0	0	112.4	L233 C234 G235 L240 W241	L233-A237 WeakPolarHBondContact O-CB 3.08Å; L233-A237 PolarHBondContact O-N 3.2Å; C234-A237 PolarHBondContact O-N 2.88Å; G235-A237 VanDerWaalsContact C-N 3.35Å; G235-A237 PolarHBondContact O-N 2.71Å; A237-L240 PolarHBondContact O-N 3.5Å; A237-W241 WeakPolarHBondContact O-CB 3.44Å; A237-W241 PolarHBondContact O-N 3.07Å
238	G	94.8	Very high	93.9	Very high	0 Å²	0	44.6 Å²	44.6	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-67.4	-40.5	174	0	0	0	0	0	114.1	C234 G235 G236 L240 W241 F242	C234-G238 PolarHBondContact O-N 3.01Å; C234-G238 VanDerWaalsContact O-N 3.11Å; G235-G238 PolarHBondContact O-N 3.34Å; G236-G238 VanDerWaalsContact C-N 3.33Å; G236-G238 PolarHBondContact O-N 3.38Å; G238-L240 VanDerWaalsContact C-N 3.35Å; G238-L240 PolarHBondContact O-N 3.48Å; G238-W241 PolarHBondContact O-N 2.82Å; G238-F242 PolarHBondContact O-N 3.21Å
239	C	95.9	Very high	93.8	Very high	31 Å²	31	43.4 Å²	43.4	21%	0.209	24%	0.238	C	C	.	.	H	α-helix	trans	-61.7	-43.3	172.2	-69.7	0	0	0	0	111.7	G235 G236 F242 I243	G235-C239 PolarHBondContact O-N 2.84Å; G235-C239 PolarHBondContact O-SG 3.32Å; G236-C239 PolarHBondContact O-N 3.47Å; C239-F242 PolarHBondContact O-N 3.43Å; C239-I243 WeakPolarHBondContact O-CG1 2.98Å; C239-I243 PolarHBondContact O-N 2.73Å
240	L	95.9	Very high	93.5	Very high	95 Å²	95	43.5 Å²	43.5	50%	0.497	24%	0.237	S	C	.	.	H	α-helix	trans	-63.3	-44.4	176.5	-179.4	61.5	0	0	0	111.6	G236 A237 G238 F242 I243 F244	G236-L240 WeakPolarHBondContact O-CB 3.22Å; G236-L240 PolarHBondContact O-N 3Å; A237-L240 PolarHBondContact O-N 3.5Å; G238-L240 VanDerWaalsContact C-N 3.35Å; G238-L240 PolarHBondContact O-N 3.48Å; L240-F242 VanDerWaalsContact C-N 3.29Å; L240-F242 PolarHBondContact O-N 3.4Å; L240-I243 WeakPolarHBondContact O-CB 3.48Å; L240-I243 PolarHBondContact O-N 3.17Å; L240-F244 HydrophobicContact CD1-CD2 4.32Å; L240-F244 HydrophobicContact CD1-CE2 3.73Å; L240-F244 HydrophobicContact CD2-CE2 4.42Å; L240-F244 HydrophobicContact CG-CD2 4.22Å; L240-F244 HydrophobicContact CG-CE2 3.82Å; L240-F244 VanDerWaalsContact O-CD2 3.24Å; L240-F244 WeakPolarHBondContact O-CD2 3.41Å; L240-F244 PolarHBondContact O-N 2.97Å
241	W	96.3	Very high	92.9	Very high	14 Å²	14	45.2 Å²	45.2	5%	0.053	25%	0.246	C	C	.	.	H	α-helix	trans	-59.1	-41.4	175.2	177	91	0	0	0	111.7	L40 G44 L140 V144 A237 G238 I243 F244 W245	L40-W241 PolarHBondContact O-NE1 3.31Å; G44-W241 VanDerWaalsContact CA-NE1 3.27Å; G44-W241 VanDerWaalsContact N-NE1 3.12Å; L140-W241 HydrophobicContact CD2-CH2 3.46Å; L140-W241 VanDerWaalsContact CD2-CH2 3.46Å; L140-W241 HydrophobicContact CD2-CZ2 4.18Å; L140-W241 HydrophobicContact CD2-CZ3 4.39Å; V144-W241 HydrophobicContact CB-CE3 4.09Å; V144-W241 HydrophobicContact CB-CZ3 3.67Å; V144-W241 HydrophobicContact CG1-CE3 3.55Å; V144-W241 HydrophobicContact CG1-CZ3 3.69Å; V144-W241 HydrophobicContact CG2-CH2 4.3Å; V144-W241 HydrophobicContact CG2-CZ3 3.86Å; A237-W241 WeakPolarHBondContact O-CB 3.44Å; A237-W241 PolarHBondContact O-N 3.07Å; G238-W241 PolarHBondContact O-N 2.82Å; W241-I243 VanDerWaalsContact C-N 3.33Å; W241-I243 PolarHBondContact O-N 3.46Å; W241-F244 PolarHBondContact O-N 2.96Å; W241-F244 VanDerWaalsContact O-N 3.16Å; W241-W245 HydrophobicContact CE3-CB 4.3Å; W241-W245 HydrophobicContact CH2-CB 3.89Å; W241-W245 AromaticContact CH2-CD2 3.49Å; W241-W245 HydrophobicContact CH2-CD2 3.49Å; W241-W245 VanDerWaalsContact CH2-CD2 3.49Å; W241-W245 AromaticContact CH2-CE3 3.49Å; W241-W245 HydrophobicContact CH2-CE3 3.49Å; W241-W245 VanDerWaalsContact CH2-CE3 3.49Å; W241-W245 AromaticContact CH2-CG 3.67Å; W241-W245 HydrophobicContact CH2-CG 3.67Å; W241-W245 HydrophobicContact CH2-CZ3 4.2Å; W241-W245 HydrophobicContact CZ2-CB 4.26Å; W241-W245 AromaticContact CZ2-CD2 3.87Å; W241-W245 HydrophobicContact CZ2-CD2 3.87Å; W241-W245 AromaticContact CZ2-CE3 3.35Å; W241-W245 HydrophobicContact CZ2-CE3 3.35Å; W241-W245 HydrophobicContact CZ2-CG 4.26Å; W241-W245 AromaticContact CZ2-CZ3 3.95Å; W241-W245 HydrophobicContact CZ2-CZ3 3.95Å; W241-W245 HydrophobicContact CZ3-CB 3.94Å; W241-W245 HydrophobicContact CZ3-CD2 4.3Å; W241-W245 HydrophobicContact CZ3-CG 4.01Å; W241-W245 PolarHBondContact O-N 3.01Å
242	F	95.9	Very high	92.3	Very high	32 Å²	32	47.4 Å²	47.4	14%	0.14	26%	0.258	C	S	.	.	H	α-helix	trans	-61.9	-38	177.4	176.4	-111	0	0	0	112.7	G141 M142 F145 G238 C239 L240 F244 W245 C246	G141-F242 WeakPolarHBondContact O-CD2 3.38Å; G141-F242 VanDerWaalsContact O-CE2 3.32Å; G141-F242 WeakPolarHBondContact O-CE2 3.4Å; M142-F242 HydrophobicContact SD-CE2 4.19Å; M142-F242 HydrophobicContact SD-CZ 3.76Å; F145-F242 HydrophobicContact CB-CB 4.14Å; F145-F242 HydrophobicContact CB-CD1 3.84Å; F145-F242 HydrophobicContact CB-CD2 3.72Å; F145-F242 HydrophobicContact CB-CE1 4.09Å; F145-F242 HydrophobicContact CB-CE2 3.97Å; F145-F242 HydrophobicContact CB-CG 3.63Å; F145-F242 HydrophobicContact CB-CZ 4.14Å; F145-F242 HydrophobicContact CD1-CE1 4.23Å; F145-F242 HydrophobicContact CD2-CB 4.18Å; F145-F242 AromaticContact CD2-CD1 3.42Å; F145-F242 HydrophobicContact CD2-CD1 3.42Å; F145-F242 VanDerWaalsContact CD2-CD1 3.42Å; F145-F242 AromaticContact CD2-CE1 3.92Å; F145-F242 HydrophobicContact CD2-CE1 3.92Å; F145-F242 AromaticContact CD2-CG 3.9Å; F145-F242 HydrophobicContact CD2-CG 3.9Å; F145-F242 HydrophobicContact CE2-CD1 4.1Å; F145-F242 HydrophobicContact CE2-CE1 4.44Å; F145-F242 AromaticContact CG-CD1 3.67Å; F145-F242 HydrophobicContact CG-CD1 3.67Å; F145-F242 HydrophobicContact CG-CD2 4.44Å; F145-F242 AromaticContact CG-CE1 3.8Å; F145-F242 HydrophobicContact CG-CE1 3.8Å; F145-F242 AromaticContact CG-CG 3.99Å; F145-F242 HydrophobicContact CG-CG 3.99Å; F145-F242 HydrophobicContact CG-CZ 4.25Å; G238-F242 PolarHBondContact O-N 3.21Å; C239-F242 PolarHBondContact O-N 3.43Å; L240-F242 VanDerWaalsContact C-N 3.29Å; L240-F242 PolarHBondContact O-N 3.4Å; F242-F244 VanDerWaalsContact C-N 3.34Å; F242-F244 PolarHBondContact O-N 2.91Å; F242-W245 WeakPolarHBondContact O-CB 3.32Å; F242-W245 PolarHBondContact O-N 2.87Å; F242-C246 VanDerWaalsContact CE2-SG 3.53Å; F242-C246 WeakPolarHBondContact CZ-SG 3.42Å; F242-C246 PolarHBondContact O-N 3.43Å; F242-C246 PolarHBondContact O-SG 3.14Å; F242-C246 VanDerWaalsContact O-SG 3.4Å
243	I	95	Very high	91.7	Very high	92 Å²	92	41.9 Å²	41.9	47%	0.472	24%	0.237	S	C	.	.	H	α-helix	trans	-59.1	-47.5	174.4	-64.9	167.6	0	0	0	110.2	C239 L240 W241 W245 C246 I247	C239-I243 WeakPolarHBondContact O-CG1 2.98Å; C239-I243 PolarHBondContact O-N 2.73Å; L240-I243 WeakPolarHBondContact O-CB 3.48Å; L240-I243 PolarHBondContact O-N 3.17Å; W241-I243 VanDerWaalsContact C-N 3.33Å; W241-I243 PolarHBondContact O-N 3.46Å; I243-W245 VanDerWaalsContact C-N 3.34Å; I243-W245 PolarHBondContact O-N 2.71Å; I243-C246 PolarHBondContact O-N 3.38Å; I243-I247 HydrophobicContact CG2-CD1 3.89Å; I243-I247 WeakPolarHBondContact O-CD1 3.29Å; I243-I247 VanDerWaalsContact O-CG1 3.3Å; I243-I247 WeakPolarHBondContact O-CG1 3.1Å; I243-I247 PolarHBondContact O-N 2.85Å
244	F	93.7	Very high	91.1	Very high	102 Å²	102	44.9 Å²	44.9	45%	0.447	24%	0.242	S	C	.	.	H	α-helix	trans	-63.4	-40.1	175.7	-72	-66.7	0	0	0	112.2	L40 L240 W241 F242 C246 I247 L248	L40-F244 HydrophobicContact CD2-CB 4.49Å; L240-F244 HydrophobicContact CD1-CD2 4.32Å; L240-F244 HydrophobicContact CD1-CE2 3.73Å; L240-F244 HydrophobicContact CD2-CE2 4.42Å; L240-F244 HydrophobicContact CG-CD2 4.22Å; L240-F244 HydrophobicContact CG-CE2 3.82Å; L240-F244 VanDerWaalsContact O-CD2 3.24Å; L240-F244 WeakPolarHBondContact O-CD2 3.41Å; L240-F244 PolarHBondContact O-N 2.97Å; W241-F244 PolarHBondContact O-N 2.96Å; W241-F244 VanDerWaalsContact O-N 3.16Å; F242-F244 VanDerWaalsContact C-N 3.34Å; F242-F244 PolarHBondContact O-N 2.91Å; F244-C246 PolarHBondContact O-N 2.97Å; F244-I247 PolarHBondContact O-N 2.94Å; F244-L248 HydrophobicContact CB-CD1 4.26Å; F244-L248 HydrophobicContact CD1-CD1 4.28Å; F244-L248 VanDerWaalsContact O-CB 3.27Å; F244-L248 WeakPolarHBondContact O-CB 3.2Å; F244-L248 VanDerWaalsContact O-CG 3.3Å; F244-L248 WeakPolarHBondContact O-CG 3.37Å; F244-L248 PolarHBondContact O-N 3.25Å
245	W	94.3	Very high	90.6	Very high	1 Å²	1	48.3 Å²	48.3	0%	0.004	26%	0.262	C	S	.	.	H	α-helix	trans	-58.8	-46.8	176.5	-178	-103.1	0	0	0	112.3	L37 L40 M41 K137 L140 G141 M186 W241 F242 I243 I247 V249	L37-W245 HydrophobicContact CD1-CH2 4.05Å; L37-W245 HydrophobicContact CD1-CZ3 4.1Å; L40-W245 HydrophobicContact CB-CE3 4.45Å; L40-W245 HydrophobicContact CB-CZ3 4.43Å; M41-W245 HydrophobicContact CE-CH2 4.03Å; M41-W245 HydrophobicContact CG-CH2 4.04Å; M41-W245 HydrophobicContact CG-CZ3 3.97Å; K137-W245 HydrophobicContact CG-CZ2 4.38Å; K137-W245 PolarHBondContact O-NE1 3.4Å; L140-W245 HydrophobicContact CB-CZ2 4.21Å; L140-W245 HydrophobicContact CD2-CD2 4.34Å; L140-W245 HydrophobicContact CD2-CE3 4.43Å; L140-W245 HydrophobicContact CD2-CH2 3.73Å; L140-W245 HydrophobicContact CD2-CZ2 3.58Å; L140-W245 HydrophobicContact CD2-CZ3 4.15Å; L140-W245 HydrophobicContact CG-CZ2 4.39Å; G141-W245 VanDerWaalsContact CA-CD1 3.49Å; M186-W245 HydrophobicContact CE-CH2 4.1Å; M186-W245 HydrophobicContact CE-CZ2 4.18Å; M186-W245 HydrophobicContact SD-CH2 3.69Å; M186-W245 HydrophobicContact SD-CZ2 3.6Å; M186-W245 VanDerWaalsContact SD-CZ2 3.6Å; W241-W245 HydrophobicContact CE3-CB 4.3Å; W241-W245 HydrophobicContact CH2-CB 3.89Å; W241-W245 AromaticContact CH2-CD2 3.49Å; W241-W245 HydrophobicContact CH2-CD2 3.49Å; W241-W245 VanDerWaalsContact CH2-CD2 3.49Å; W241-W245 AromaticContact CH2-CE3 3.49Å; W241-W245 HydrophobicContact CH2-CE3 3.49Å; W241-W245 VanDerWaalsContact CH2-CE3 3.49Å; W241-W245 AromaticContact CH2-CG 3.67Å; W241-W245 HydrophobicContact CH2-CG 3.67Å; W241-W245 HydrophobicContact CH2-CZ3 4.2Å; W241-W245 HydrophobicContact CZ2-CB 4.26Å; W241-W245 AromaticContact CZ2-CD2 3.87Å; W241-W245 HydrophobicContact CZ2-CD2 3.87Å; W241-W245 AromaticContact CZ2-CE3 3.35Å; W241-W245 HydrophobicContact CZ2-CE3 3.35Å; W241-W245 HydrophobicContact CZ2-CG 4.26Å; W241-W245 AromaticContact CZ2-CZ3 3.95Å; W241-W245 HydrophobicContact CZ2-CZ3 3.95Å; W241-W245 HydrophobicContact CZ3-CB 3.94Å; W241-W245 HydrophobicContact CZ3-CD2 4.3Å; W241-W245 HydrophobicContact CZ3-CG 4.01Å; W241-W245 PolarHBondContact O-N 3.01Å; F242-W245 WeakPolarHBondContact O-CB 3.32Å; F242-W245 PolarHBondContact O-N 2.87Å; I243-W245 VanDerWaalsContact C-N 3.34Å; I243-W245 PolarHBondContact O-N 2.71Å; W245-I247 VanDerWaalsContact C-N 3.3Å; W245-I247 PolarHBondContact O-N 3.38Å; W245-V249 HydrophobicContact CD2-CB 4.1Å; W245-V249 HydrophobicContact CD2-CG1 4.37Å; W245-V249 HydrophobicContact CD2-CG2 3.94Å; W245-V249 HydrophobicContact CE3-CB 4.14Å; W245-V249 HydrophobicContact CE3-CG1 4.4Å; W245-V249 HydrophobicContact CE3-CG2 3.5Å; W245-V249 HydrophobicContact CH2-CB 4.4Å; W245-V249 HydrophobicContact CH2-CG1 3.78Å; W245-V249 HydrophobicContact CH2-CG2 4.19Å; W245-V249 HydrophobicContact CZ2-CB 4.38Å; W245-V249 HydrophobicContact CZ2-CG1 3.75Å; W245-V249 HydrophobicContact CZ3-CB 4.3Å; W245-V249 HydrophobicContact CZ3-CG1 4.12Å; W245-V249 HydrophobicContact CZ3-CG2 3.65Å; W245-V249 WeakPolarHBondContact O-CB 3.26Å; W245-V249 PolarHBondContact O-N 3.11Å; W245-V249 VanDerWaalsContact O-N 3.13Å
246	C	92	Very high	90.1	Very high	57 Å²	57	49.6 Å²	49.6	39%	0.385	27%	0.268	S	S	.	.	H	α-helix	trans	-60.8	-39.4	178.8	-73.6	0	0	0	0	112.8	K137 F242 I243 F244	K137-C246 PolarHBondContact NZ-O 2.95Å; F242-C246 VanDerWaalsContact CE2-SG 3.53Å; F242-C246 WeakPolarHBondContact CZ-SG 3.42Å; F242-C246 PolarHBondContact O-N 3.43Å; F242-C246 PolarHBondContact O-SG 3.14Å; F242-C246 VanDerWaalsContact O-SG 3.4Å; I243-C246 PolarHBondContact O-N 3.38Å; F244-C246 PolarHBondContact O-N 2.97Å
247	I	91.1	Very high	89.3	Confident	108 Å²	108	59.6 Å²	59.6	55%	0.554	30%	0.295	S	S	*	.	H	α-helix	trans	-79.5	-41.1	-175.6	-63.3	167.8	0	0	0	111.9	I243 F244 W245	I243-I247 HydrophobicContact CG2-CD1 3.89Å; I243-I247 WeakPolarHBondContact O-CD1 3.29Å; I243-I247 VanDerWaalsContact O-CG1 3.3Å; I243-I247 WeakPolarHBondContact O-CG1 3.1Å; I243-I247 PolarHBondContact O-N 2.85Å; F244-I247 PolarHBondContact O-N 2.94Å; W245-I247 VanDerWaalsContact C-N 3.3Å; W245-I247 PolarHBondContact O-N 3.38Å
248	L	89.4	Confident	88.7	Confident	47 Å²	47	65.8 Å²	65.8	25%	0.246	31%	0.309	C	S	.	.	H	α-helix	trans	-96.4	-22.3	-166.8	-61	177.4	0	0	0	114.1	L40 F244 H256	L40-L248 HydrophobicContact CD1-CB 3.64Å; L40-L248 HydrophobicContact CD1-CD1 3.83Å; L40-L248 HydrophobicContact CD1-CG 4.39Å; L40-L248 HydrophobicContact CD2-CD1 4.21Å; F244-L248 HydrophobicContact CB-CD1 4.26Å; F244-L248 HydrophobicContact CD1-CD1 4.28Å; F244-L248 VanDerWaalsContact O-CB 3.27Å; F244-L248 WeakPolarHBondContact O-CB 3.2Å; F244-L248 VanDerWaalsContact O-CG 3.3Å; F244-L248 WeakPolarHBondContact O-CG 3.37Å; F244-L248 PolarHBondContact O-N 3.25Å; L248-H256 PolarHBondContact O-NE2 2.78Å
249	V	90.4	Very high	88.2	Confident	3 Å²	3	67 Å²	67	2%	0.018	32%	0.315	C	S	.	.			trans	-107.6	147.6	-170.6	177.9	0	0	0	0	112.2	L37 L40 K137 M186 W245	L37-V249 HydrophobicContact CD1-CB 4.31Å; L37-V249 HydrophobicContact CD1-CG1 3.57Å; L37-V249 HydrophobicContact CD1-CG2 3.78Å; L40-V249 HydrophobicContact CD1-CG2 3.81Å; K137-V249 HydrophobicContact CD-CG1 4.45Å; K137-V249 WeakPolarHBondContact CD-O 3.48Å; K137-V249 WeakPolarHBondContact CE-O 3.41Å; K137-V249 HydrophobicContact CG-CG1 4.19Å; K137-V249 PolarHBondContact NZ-O 3.45Å; M186-V249 HydrophobicContact CE-CG1 3.63Å; W245-V249 HydrophobicContact CD2-CB 4.1Å; W245-V249 HydrophobicContact CD2-CG1 4.37Å; W245-V249 HydrophobicContact CD2-CG2 3.94Å; W245-V249 HydrophobicContact CE3-CB 4.14Å; W245-V249 HydrophobicContact CE3-CG1 4.4Å; W245-V249 HydrophobicContact CE3-CG2 3.5Å; W245-V249 HydrophobicContact CH2-CB 4.4Å; W245-V249 HydrophobicContact CH2-CG1 3.78Å; W245-V249 HydrophobicContact CH2-CG2 4.19Å; W245-V249 HydrophobicContact CZ2-CB 4.38Å; W245-V249 HydrophobicContact CZ2-CG1 3.75Å; W245-V249 HydrophobicContact CZ3-CB 4.3Å; W245-V249 HydrophobicContact CZ3-CG1 4.12Å; W245-V249 HydrophobicContact CZ3-CG2 3.65Å; W245-V249 WeakPolarHBondContact O-CB 3.26Å; W245-V249 PolarHBondContact O-N 3.11Å; W245-V249 VanDerWaalsContact O-N 3.13Å
250	S	86.7	Confident	87.7	Confident	20 Å²	20	68.2 Å²	68.2	14%	0.14	32%	0.324	C	S	.	.			trans	-133	148.9	173.4	-56.8	0	0	0	0	110.2	W190	W190-S250 VanDerWaalsContact CZ2-O 3.3Å; W190-S250 WeakPolarHBondContact CZ2-O 3.19Å; W190-S250 PolarHBondContact NE1-O 2.8Å
251	D	81.5	Confident	87.1	Confident	36 Å²	36	71 Å²	71	19%	0.193	34%	0.335	C	S	.	.	S	Bend	trans	-65.9	-39	-178.8	-83.3	-61.7	0	0	0	112.8	G135 G136 K137 W190	G135-D251 VanDerWaalsContact C-OD1 3.27Å; G135-D251 WeakPolarHBondContact CA-OD1 3.49Å; G136-D251 PolarHBondContact N-OD1 3.32Å; G136-D251 VanDerWaalsContact N-OD1 3.15Å; K137-D251 WeakPolarHBondContact CA-OD1 3.36Å; K137-D251 HydrophobicContact CB-CB 4.48Å; K137-D251 WeakPolarHBondContact CB-OD1 3.07Å; K137-D251 WeakPolarHBondContact CB-OD2 3.34Å; K137-D251 PolarHBondContact N-OD1 3.48Å; W190-D251 PolarHBondContact NE1-O 2.88Å
252	D	81.6	Confident	86.5	Confident	46 Å²	46	77.7 Å²	77.7	25%	0.246	37%	0.366	C	S	.	.	S	Bend	trans	-121.1	134.9	-176.4	-166.1	-55.7	0	0	0	110.1	R254 T255 H256	D252-R254 PolarHBondContact O-N 3.36Å; D252-R254 VanDerWaalsContact O-N 3.1Å; D252-R254 WeakPolarHBondContact OD1-CB 3.36Å; D252-R254 WeakPolarHBondContact OD1-CD 3.23Å; D252-R254 WeakPolarHBondContact OD1-CG 3.22Å; D252-R254 PolarHBondContact OD1-N 3.36Å; D252-T255 HydrophobicContact CB-CG2 4.24Å; D252-T255 PolarHBondContact O-N 3.27Å; D252-T255 PolarHBondContact O-OG1 3.3Å; D252-H256 PolarHBondContact O-N 3.32Å
253	P	81.6	Confident	85.9	Confident	4 Å²	4	76.5 Å²	76.5	3%	0.026	36%	0.361	C	S	.	.	G	3₁₀ helix	trans	-50.2	-32.2	172.1	-25.8	32.7	0	0	0	113.5	R189 W190 T255 H256 I259 I267	R189-P253 WeakPolarHBondContact O-CG 3.25Å; W190-P253 HydrophobicContact CD2-CG 3.94Å; W190-P253 HydrophobicContact CE3-CG 4.3Å; W190-P253 HydrophobicContact CG-CG 4.26Å; W190-P253 HydrophobicContact CZ2-CG 4.29Å; P253-T255 VanDerWaalsContact C-N 3.3Å; P253-T255 PolarHBondContact O-N 3.39Å; P253-H256 WeakPolarHBondContact O-CB 3.28Å; P253-H256 PolarHBondContact O-N 2.96Å; P253-I259 HydrophobicContact CB-CD1 4.13Å; P253-I267 HydrophobicContact CB-CD1 4.31Å; P253-I267 HydrophobicContact CB-CG2 4.42Å; P253-I267 HydrophobicContact CG-CD1 4.4Å; P253-I267 HydrophobicContact CG-CG2 3.9Å
254	R	80.8	Confident	85.4	Confident	155 Å²	155	76.4 Å²	76.4	59%	0.585	36%	0.355	S	S	*	.	G	3₁₀ helix	trans	-66.9	-29.6	178.1	-62.2	168.1	-177.1	-158.6	1.1	113.4	D252 I268	D252-R254 PolarHBondContact O-N 3.36Å; D252-R254 VanDerWaalsContact O-N 3.1Å; D252-R254 WeakPolarHBondContact OD1-CB 3.36Å; D252-R254 WeakPolarHBondContact OD1-CD 3.23Å; D252-R254 WeakPolarHBondContact OD1-CG 3.22Å; D252-R254 PolarHBondContact OD1-N 3.36Å; R254-I268 HydrophobicContact CG-CD1 3.72Å
255	T	82.3	Confident	84.9	Confident	92 Å²	92	75.3 Å²	75.3	56%	0.564	35%	0.354	S	S	*	.	G	3₁₀ helix	trans	-93.3	-6.9	-178.7	61.1	0	0	0	0	112.7	D252 P253 R257	D252-T255 HydrophobicContact CB-CG2 4.24Å; D252-T255 PolarHBondContact O-N 3.27Å; D252-T255 PolarHBondContact O-OG1 3.3Å; P253-T255 VanDerWaalsContact C-N 3.3Å; P253-T255 PolarHBondContact O-N 3.39Å; T255-R257 PolarHBondContact O-N 3.31Å
256	H	83.4	Confident	84.4	Confident	26 Å²	26	77.2 Å²	77.2	12%	0.12	36%	0.361	C	S	.	.			trans	-73.3	121.2	-173.5	-168.8	-90.2	0	0	0	111.6	W190 L248 D252 P253 R258 I259	W190-H256 HydrophobicContact CH2-CB 3.8Å; W190-H256 AromaticContact CH2-CD2 3.36Å; W190-H256 WeakPolarHBondContact CH2-CD2 3.47Å; W190-H256 AromaticContact CH2-CG 3.63Å; W190-H256 HydrophobicContact CZ2-CB 4.17Å; W190-H256 AromaticContact CZ2-CD2 3.87Å; L248-H256 PolarHBondContact O-NE2 2.78Å; D252-H256 PolarHBondContact O-N 3.32Å; P253-H256 WeakPolarHBondContact O-CB 3.28Å; P253-H256 PolarHBondContact O-N 2.96Å; H256-R258 VanDerWaalsContact C-N 3.34Å; H256-R258 PolarHBondContact ND1-N 2.98Å; H256-R258 PolarHBondContact O-N 3.44Å; H256-I259 HydrophobicContact CB-CB 4.14Å; H256-I259 HydrophobicContact CB-CG2 4.04Å; H256-I259 PolarHBondContact ND1-N 3.24Å; H256-I259 WeakPolarHBondContact O-CG2 3.5Å
257	R	78.4	Confident	84	Confident	244 Å²	244	74.5 Å²	74.5	92%	0.921	34%	0.343	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.4	-26.7	-173.8	-71.2	-178.2	173.9	-177.6	-2.3	115	T255	T255-R257 PolarHBondContact O-N 3.31Å
258	R	81	Confident	83.6	Confident	176 Å²	176	71.4 Å²	71.4	66%	0.664	33%	0.327	S	S	*	.	T	Hydrogen-bonded Turn	trans	-112.1	8.3	-170.6	-61.3	-178.3	-178.7	177.7	2.3	114	H256	H256-R258 VanDerWaalsContact C-N 3.34Å; H256-R258 PolarHBondContact ND1-N 2.98Å; H256-R258 PolarHBondContact O-N 3.44Å
259	I	85.5	Confident	83.3	Confident	26 Å²	26	75.2 Å²	75.2	13%	0.133	35%	0.348	C	S	.	.			trans	-80.6	141.8	-179	-163.1	166.9	0	0	0	109.5	A33 W190 P253 H256 E263 R264 I267	A33-I259 HydrophobicContact CB-CB 4.31Å; A33-I259 HydrophobicContact CB-CD1 4.35Å; A33-I259 HydrophobicContact CB-CG1 3.99Å; W190-I259 HydrophobicContact CZ3-CD1 4.34Å; P253-I259 HydrophobicContact CB-CD1 4.13Å; H256-I259 HydrophobicContact CB-CB 4.14Å; H256-I259 HydrophobicContact CB-CG2 4.04Å; H256-I259 PolarHBondContact ND1-N 3.24Å; H256-I259 WeakPolarHBondContact O-CG2 3.5Å; I259-E263 HydrophobicContact CD1-CG 4.24Å; I259-E263 HydrophobicContact CG1-CB 4.09Å; I259-E263 HydrophobicContact CG1-CG 4.2Å; I259-R264 HydrophobicContact CD1-CB 4.12Å; I259-R264 HydrophobicContact CG1-CB 4.34Å; I259-R264 HydrophobicContact CG2-CB 4.16Å; I259-I267 HydrophobicContact CD1-CD1 3.93Å
260	S	85.5	Confident	82.8	Confident	57 Å²	57	77 Å²	77	40%	0.399	36%	0.36	S	S	.	.			trans	-73.7	148.7	171.1	66.5	0	0	0	0	110.2	Q262 E263 R264	S260-Q262 VanDerWaalsContact C-N 3.26Å; S260-Q262 PolarHBondContact O-N 3.09Å; S260-E263 PolarHBondContact O-N 2.99Å; S260-E263 VanDerWaalsContact OG-CB 3.23Å; S260-E263 WeakPolarHBondContact OG-CB 3.26Å; S260-E263 PolarHBondContact OG-N 3.03Å; S260-R264 WeakPolarHBondContact O-CB 3.42Å; S260-R264 PolarHBondContact O-N 3.07Å
261	E	83.6	Confident	82.3	Confident	153 Å²	153	77 Å²	77	72%	0.715	36%	0.359	S	S	*	.	H	α-helix	trans	-59.8	-40	178.1	-67.8	-175.7	162.6	0	0	111.5	E263 R264 D265	E261-E263 PolarHBondContact O-N 2.72Å; E261-R264 PolarHBondContact O-N 2.81Å; E261-D265 WeakPolarHBondContact O-CB 3.39Å; E261-D265 PolarHBondContact O-N 3.09Å
262	Q	82.6	Confident	81.3	Confident	154 Å²	154	77.4 Å²	77.4	72%	0.72	37%	0.371	S	S	*	.	H	α-helix	trans	-58.5	-45.2	175.4	-65.5	176.2	-4.9	0	0	112.7	S260 Y266	S260-Q262 VanDerWaalsContact C-N 3.26Å; S260-Q262 PolarHBondContact O-N 3.09Å; Q262-Y266 WeakPolarHBondContact O-CB 3.21Å; Q262-Y266 PolarHBondContact O-N 2.9Å
263	E	83.2	Confident	79.7	Confident	8 Å²	8	79.2 Å²	79.2	4%	0.037	39%	0.392	C	S	.	.	H	α-helix	trans	-70.1	-40.2	178.8	-175.9	177.9	-175.4	0	0	111.2	S32 A33 R34 I259 S260 E261 Y266 I267	S32-E263 WeakPolarHBondContact CB-OE1 3.47Å; A33-E263 PolarHBondContact N-OE1 3.4Å; A33-E263 PolarHBondContact N-OE2 2.99Å; R34-E263 VanDerWaalsContact CG-OE1 3.28Å; R34-E263 WeakPolarHBondContact CG-OE1 3.47Å; R34-E263 IonicContact CZ-OE1 3.25Å; R34-E263 PolarHBondContact N-OE1 3.33Å; R34-E263 VanDerWaalsContact N-OE1 3.15Å; R34-E263 IonicContact NE-OE1 3.09Å; R34-E263 PolarHBondContact NE-OE1 3.3Å; R34-E263 IonicContact NH2-OE1 3.5Å; I259-E263 HydrophobicContact CD1-CG 4.24Å; I259-E263 HydrophobicContact CG1-CB 4.09Å; I259-E263 HydrophobicContact CG1-CG 4.2Å; S260-E263 PolarHBondContact O-N 2.99Å; S260-E263 VanDerWaalsContact OG-CB 3.23Å; S260-E263 WeakPolarHBondContact OG-CB 3.26Å; S260-E263 PolarHBondContact OG-N 3.03Å; E261-E263 PolarHBondContact O-N 2.72Å; E263-Y266 PolarHBondContact O-N 3.19Å; E263-I267 HydrophobicContact CG-CD1 4.06Å; E263-I267 VanDerWaalsContact O-CG1 3.25Å; E263-I267 WeakPolarHBondContact O-CG1 3.35Å; E263-I267 PolarHBondContact O-N 3.31Å
264	R	84.1	Confident	78.1	Confident	90 Å²	90	85.9 Å²	85.9	34%	0.34	42%	0.423	S	S	.	.	H	α-helix	trans	-58.9	-49.2	176.8	177.4	-174.2	168.9	-155.2	-2.7	111.3	I259 S260 E261 I267 I268	I259-R264 HydrophobicContact CD1-CB 4.12Å; I259-R264 HydrophobicContact CG1-CB 4.34Å; I259-R264 HydrophobicContact CG2-CB 4.16Å; S260-R264 WeakPolarHBondContact O-CB 3.42Å; S260-R264 PolarHBondContact O-N 3.07Å; E261-R264 PolarHBondContact O-N 2.81Å; R264-I267 PolarHBondContact O-N 3.38Å; R264-I268 HydrophobicContact CG-CD1 3.74Å; R264-I268 VanDerWaalsContact O-CG1 3.32Å; R264-I268 WeakPolarHBondContact O-CG1 3.34Å; R264-I268 PolarHBondContact O-N 3.46Å
265	D	84.2	Confident	76.3	Confident	79 Å²	79	81 Å²	81	42%	0.422	42%	0.422	S	S	.	.	H	α-helix	trans	-68.8	-37.7	-178.1	-68.8	-15.4	0	0	0	111.1	E261 I267 I268 N269	E261-D265 WeakPolarHBondContact O-CB 3.39Å; E261-D265 PolarHBondContact O-N 3.09Å; D265-I267 PolarHBondContact O-N 2.94Å; D265-I268 PolarHBondContact O-N 3.45Å; D265-N269 WeakPolarHBondContact O-CB 3.41Å; D265-N269 PolarHBondContact O-N 2.8Å; D265-N269 PolarHBondContact O-ND2 3.26Å; D265-N269 VanDerWaalsContact O-ND2 3.15Å
266	Y	84.3	Confident	74.2	Confident	40 Å²	40	84.7 Å²	84.7	16%	0.157	43%	0.43	C	S	.	.	H	α-helix	trans	-56.7	-46.6	171.5	174.1	-108.8	0	0	0	112.1	A25 P192 Q262 E263 S270	A25-Y266 WeakPolarHBondContact O-CD2 3.4Å; P192-Y266 HydrophobicContact CB-CE1 4.12Å; P192-Y266 HydrophobicContact CG-CD1 4.23Å; P192-Y266 HydrophobicContact CG-CE1 3.67Å; Q262-Y266 WeakPolarHBondContact O-CB 3.21Å; Q262-Y266 PolarHBondContact O-N 2.9Å; E263-Y266 PolarHBondContact O-N 3.19Å; Y266-S270 WeakPolarHBondContact O-CB 3.31Å; Y266-S270 PolarHBondContact O-N 3.47Å; Y266-S270 PolarHBondContact O-OG 2.98Å
267	I	83.1	Confident	72.4	Confident	1 Å²	1	86.9 Å²	86.9	1%	0.005	46%	0.459	C	S	.	.	H	α-helix	trans	-64.5	-49.6	178.7	-65.4	166.7	0	0	0	110.8	R34 P192 P253 I259 E263 R264 D265 N269 S270 I271	R34-I267 VanDerWaalsContact CD-CD1 3.5Å; R34-I267 HydrophobicContact CG-CD1 3.72Å; R34-I267 HydrophobicContact CG-CG1 4.47Å; P192-I267 HydrophobicContact CG-CG1 4.32Å; P253-I267 HydrophobicContact CB-CD1 4.31Å; P253-I267 HydrophobicContact CB-CG2 4.42Å; P253-I267 HydrophobicContact CG-CD1 4.4Å; P253-I267 HydrophobicContact CG-CG2 3.9Å; I259-I267 HydrophobicContact CD1-CD1 3.93Å; E263-I267 HydrophobicContact CG-CD1 4.06Å; E263-I267 VanDerWaalsContact O-CG1 3.25Å; E263-I267 WeakPolarHBondContact O-CG1 3.35Å; E263-I267 PolarHBondContact O-N 3.31Å; R264-I267 PolarHBondContact O-N 3.38Å; D265-I267 PolarHBondContact O-N 2.94Å; I267-N269 VanDerWaalsContact C-N 3.33Å; I267-N269 PolarHBondContact O-N 3Å; I267-S270 PolarHBondContact O-N 3.1Å; I267-S270 PolarHBondContact O-OG 3.22Å; I267-S270 VanDerWaalsContact O-OG 3.13Å; I267-I271 HydrophobicContact CG2-CD1 3.52Å; I267-I271 HydrophobicContact CG2-CG1 4.29Å; I267-I271 WeakPolarHBondContact O-CB 3.49Å; I267-I271 VanDerWaalsContact O-CG1 3.29Å; I267-I271 WeakPolarHBondContact O-CG1 3.33Å; I267-I271 PolarHBondContact O-N 3.25Å
268	I	83.4	Confident	71	Confident	43 Å²	43	80.3 Å²	80.3	22%	0.221	44%	0.439	C	S	.	.	H	α-helix	trans	-63.1	-42.5	-176.7	-67.2	169.6	0	0	0	110.7	R254 R264 D265 G272	R254-I268 HydrophobicContact CG-CD1 3.72Å; R264-I268 HydrophobicContact CG-CD1 3.74Å; R264-I268 VanDerWaalsContact O-CG1 3.32Å; R264-I268 WeakPolarHBondContact O-CG1 3.34Å; R264-I268 PolarHBondContact O-N 3.46Å; D265-I268 PolarHBondContact O-N 3.45Å; I268-G272 PolarHBondContact O-N 3.33Å
269	N	83	Confident	69.2	Low	126 Å²	126	74.7 Å²	74.7	67%	0.674	44%	0.436	S	S	*	.	H	α-helix	trans	-73.7	-35.1	-179	-66.2	-22.8	0	0	0	112.4	D265 I267	D265-N269 WeakPolarHBondContact O-CB 3.41Å; D265-N269 PolarHBondContact O-N 2.8Å; D265-N269 PolarHBondContact O-ND2 3.26Å; D265-N269 VanDerWaalsContact O-ND2 3.15Å; I267-N269 VanDerWaalsContact C-N 3.33Å; I267-N269 PolarHBondContact O-N 3Å
270	S	78.5	Confident	67.3	Low	40 Å²	40	84 Å²	84	28%	0.28	47%	0.469	S	S	.	.	H	α-helix	trans	-77.4	-29.4	178.6	60.8	0	0	0	0	113.9	P192 P193 Y266 I267	P192-S270 WeakPolarHBondContact CB-OG 3.47Å; P193-S270 WeakPolarHBondContact CD-O 3.25Å; Y266-S270 WeakPolarHBondContact O-CB 3.31Å; Y266-S270 PolarHBondContact O-N 3.47Å; Y266-S270 PolarHBondContact O-OG 2.98Å; I267-S270 PolarHBondContact O-N 3.1Å; I267-S270 PolarHBondContact O-OG 3.22Å; I267-S270 VanDerWaalsContact O-OG 3.13Å
271	I	75.9	Confident	65.9	Low	22 Å²	22	84.3 Å²	84.3	11%	0.113	47%	0.471	C	S	.	.	H	α-helix	trans	-81.6	-35.2	173.8	-63.9	177.3	0	0	0	110.3	R189 I267 Q274	R189-I271 WeakPolarHBondContact O-CD1 3.31Å; I267-I271 HydrophobicContact CG2-CD1 3.52Å; I267-I271 HydrophobicContact CG2-CG1 4.29Å; I267-I271 WeakPolarHBondContact O-CB 3.49Å; I267-I271 VanDerWaalsContact O-CG1 3.29Å; I267-I271 WeakPolarHBondContact O-CG1 3.33Å; I267-I271 PolarHBondContact O-N 3.25Å; I271-Q274 VanDerWaalsContact O-CB 3.29Å; I271-Q274 WeakPolarHBondContact O-CB 3.5Å; I271-Q274 PolarHBondContact O-N 2.89Å
272	G	62	Low	65.1	Low	43 Å²	43	80.4 Å²	80.4	44%	0.443	46%	0.455	S	S	.	.	G	3₁₀ helix	trans	54.3	-157.8	175.2	0	0	0	0	0	114.5	I268 Q274 G275	I268-G272 PolarHBondContact O-N 3.33Å; G272-Q274 PolarHBondContact O-N 3.45Å; G272-Q274 VanDerWaalsContact O-N 3.14Å; G272-G275 PolarHBondContact O-N 2.86Å
273	A	48.4	Very low	64.7	Low	85 Å²	85	74.4 Å²	74.4	70%	0.702	43%	0.43	S	S	*	.	G	3₁₀ helix	trans	-66.6	-6.4	175.8	0	0	0	0	0	114.1	G275 K276	A273-G275 PolarHBondContact O-N 3.48Å; A273-K276 PolarHBondContact O-N 3.43Å; A273-K276 VanDerWaalsContact O-N 3.14Å
274	Q	46.9	Very low	64.6	Low	143 Å²	143	79 Å²	79	67%	0.668	45%	0.454	S	S	*	.	G	3₁₀ helix	trans	-66.3	-12.6	173.1	-64.9	-83.4	-22.2	0	0	112.7	I271 G272 K276	I271-Q274 VanDerWaalsContact O-CB 3.29Å; I271-Q274 WeakPolarHBondContact O-CB 3.5Å; I271-Q274 PolarHBondContact O-N 2.89Å; G272-Q274 PolarHBondContact O-N 3.45Å; G272-Q274 VanDerWaalsContact O-N 3.14Å; Q274-K276 VanDerWaalsContact C-N 3.35Å
275	G	42.1	Very low	64.3	Low	54 Å²	54	79.9 Å²	79.9	56%	0.557	47%	0.469	S	S	*	.	G	3₁₀ helix	trans	-80	-5.9	171.6	0	0	0	0	0	115.1	G272 A273 G277	G272-G275 PolarHBondContact O-N 2.86Å; A273-G275 PolarHBondContact O-N 3.48Å; G275-G277 PolarHBondContact O-N 2.95Å
276	K	40	Very low	64.1	Low	169 Å²	169	79 Å²	79	74%	0.735	47%	0.469	S	S	*	.	S	Bend	trans	-74.8	120.8	164.6	-71.4	-174.1	178.8	179.4	0	106.8	A273 Q274 H278	A273-K276 PolarHBondContact O-N 3.43Å; A273-K276 VanDerWaalsContact O-N 3.14Å; Q274-K276 VanDerWaalsContact C-N 3.35Å; K276-H278 PolarHBondContact O-N 3.45Å; K276-H278 VanDerWaalsContact O-N 3.11Å
277	G	44.5	Very low	64	Low	72 Å²	72	77.3 Å²	77.3	74%	0.742	46%	0.463	S	S	*	.			trans	-43.1	123.2	175.6	0	0	0	0	0	109.5	G275 G279	G275-G277 PolarHBondContact O-N 2.95Å; G277-G279 PolarHBondContact O-N 3.31Å
278	H	48.8	Very low	64.1	Low	106 Å²	106	79 Å²	79	49%	0.491	48%	0.48	S	S	.	.			trans	-53.1	135.4	-177.7	-75.4	52.5	0	0	0	108.7	K276	K276-H278 PolarHBondContact O-N 3.45Å; K276-H278 VanDerWaalsContact O-N 3.11Å
279	G	42.7	Very low	64.2	Low	58 Å²	58	83.5 Å²	83.5	60%	0.598	50%	0.504	S	S	*	.			trans	-48.1	145.5	-175.4	0	0	0	0	0	113.2	G277 S281	G277-G279 PolarHBondContact O-N 3.31Å; G279-S281 VanDerWaalsContact C-N 3.26Å; G279-S281 PolarHBondContact O-N 3.31Å
280	W	47.5	Very low	64.4	Low	221 Å²	221	77.9 Å²	77.9	84%	0.837	48%	0.475	S	S	*	.	S	Bend	trans	-76	41.3	-165.8	-90.9	43	0	0	0	115.5	Y129	Y129-W280 HydrophobicContact CE2-CZ2 4.37Å
281	S	56.1	Low	65	Low	63 Å²	63	79.9 Å²	79.9	44%	0.441	49%	0.485	S	S	.	.			trans	-110.9	75.9	166.2	55.8	0	0	0	0	109.6	G279 P283	G279-S281 VanDerWaalsContact C-N 3.26Å; G279-S281 PolarHBondContact O-N 3.31Å; S281-P283 WeakPolarHBondContact O-CD 3.46Å
282	L	66.8	Low	65.6	Low	71 Å²	71	79.5 Å²	79.5	37%	0.372	48%	0.484	S	S	.	.			trans	-75.3	121	166.5	-78.9	162.3	0	0	0	107.8	L284 M287 Y423 F426	L282-L284 HydrophobicContact CB-CD2 4Å; L282-L284 HydrophobicContact CB-CG 3.94Å; L282-L284 HydrophobicContact CD1-CD2 4.48Å; L282-L284 PolarHBondContact O-N 3.19Å; L282-M287 HydrophobicContact CD2-CE 4.32Å; L282-Y423 HydrophobicContact CD2-CD1 3.72Å; L282-Y423 HydrophobicContact CD2-CE1 3.91Å; L282-F426 HydrophobicContact CD1-CE1 4.5Å; L282-F426 HydrophobicContact CD1-CE2 4.31Å; L282-F426 HydrophobicContact CD1-CZ 4.28Å; L282-F426 HydrophobicContact CD2-CD1 4.14Å; L282-F426 HydrophobicContact CD2-CE1 4.37Å; L282-F426 HydrophobicContact CD2-CG 4.46Å
283	P	74.3	Confident	66.9	Low	29 Å²	29	77.7 Å²	77.7	19%	0.188	46%	0.464	C	S	.	.			trans	-75.3	66	175.2	32	-34.8	0	0	0	109.9	S281 V285 S286 M287 W487	S281-P283 WeakPolarHBondContact O-CD 3.46Å; P283-V285 VanDerWaalsContact C-N 3.26Å; P283-V285 PolarHBondContact O-N 2.94Å; P283-S286 PolarHBondContact O-N 3.11Å; P283-M287 HydrophobicContact CG-CG 4.43Å; P283-M287 WeakPolarHBondContact O-CB 3.28Å; P283-M287 WeakPolarHBondContact O-CG 3.48Å; P283-M287 PolarHBondContact O-N 2.95Å; P283-W487 HydrophobicContact CG-CB 4.4Å; P283-W487 HydrophobicContact CG-CE3 4.4Å
284	L	79.3	Confident	69	Low	103 Å²	103	79.1 Å²	79.1	54%	0.539	45%	0.451	S	S	.	.	H	α-helix	trans	-59.5	-36.4	-171.6	-70.1	175	0	0	0	112.4	L282 G288 F426	L282-L284 HydrophobicContact CB-CD2 4Å; L282-L284 HydrophobicContact CB-CG 3.94Å; L282-L284 HydrophobicContact CD1-CD2 4.48Å; L282-L284 PolarHBondContact O-N 3.19Å; L284-G288 PolarHBondContact O-N 3.46Å; L284-F426 HydrophobicContact CD2-CE1 3.98Å; L284-F426 HydrophobicContact CD2-CZ 3.85Å
285	V	79.2	Confident	71.2	Confident	109 Å²	109	72.5 Å²	72.5	66%	0.661	42%	0.421	S	S	*	.	H	α-helix	trans	-69	-49.1	178.5	-179.5	0	0	0	0	110.3	P283 M287 G288 L289	P283-V285 VanDerWaalsContact C-N 3.26Å; P283-V285 PolarHBondContact O-N 2.94Å; V285-M287 VanDerWaalsContact C-N 3.34Å; V285-M287 PolarHBondContact O-N 3.33Å; V285-G288 PolarHBondContact O-N 2.89Å; V285-G288 VanDerWaalsContact O-N 3.17Å; V285-L289 HydrophobicContact CG1-CD1 3.87Å; V285-L289 WeakPolarHBondContact O-CG 3.5Å; V285-L289 PolarHBondContact O-N 3.17Å
286	S	79.9	Confident	73.6	Confident	60 Å²	60	70 Å²	70	42%	0.42	40%	0.395	S	S	.	.	H	α-helix	trans	-64.8	-38	179.1	-46.7	0	0	0	0	112.1	P283 S290	P283-S286 PolarHBondContact O-N 3.11Å; S286-S290 PolarHBondContact O-N 2.85Å
287	M	82.8	Confident	76.2	Confident	6 Å²	6	62.1 Å²	62.1	3%	0.03	36%	0.36	C	S	.	.	H	α-helix	trans	-61.9	-48.8	170.3	-74.6	176.7	152.5	0	0	111.4	L282 P283 V285 L289 S290 L293 Y423 F426 L427 W487	L282-M287 HydrophobicContact CD2-CE 4.32Å; P283-M287 HydrophobicContact CG-CG 4.43Å; P283-M287 WeakPolarHBondContact O-CB 3.28Å; P283-M287 WeakPolarHBondContact O-CG 3.48Å; P283-M287 PolarHBondContact O-N 2.95Å; V285-M287 VanDerWaalsContact C-N 3.34Å; V285-M287 PolarHBondContact O-N 3.33Å; M287-L289 PolarHBondContact O-N 3.42Å; M287-S290 WeakPolarHBondContact O-CB 3.38Å; M287-S290 PolarHBondContact O-N 3.13Å; M287-S290 VanDerWaalsContact O-N 3.1Å; M287-L293 HydrophobicContact CB-CD2 4.4Å; M287-L293 WeakPolarHBondContact O-CD2 3.21Å; M287-Y423 HydrophobicContact CE-CD1 4Å; M287-Y423 HydrophobicContact CE-CD2 3.67Å; M287-Y423 HydrophobicContact CE-CE2 4.34Å; M287-Y423 HydrophobicContact CE-CG 3.44Å; M287-Y423 VanDerWaalsContact CE-CG 3.44Å; M287-F426 HydrophobicContact CE-CD1 4.32Å; M287-F426 HydrophobicContact SD-CD1 4.27Å; M287-F426 HydrophobicContact SD-CE1 4.08Å; M287-L427 HydrophobicContact CE-CD2 4.28Å; M287-W487 HydrophobicContact CE-CE3 3.95Å; M287-W487 HydrophobicContact CE-CH2 3.92Å; M287-W487 HydrophobicContact CE-CZ3 3.28Å; M287-W487 HydrophobicContact CG-CD2 4.1Å; M287-W487 HydrophobicContact CG-CE3 3.76Å; M287-W487 HydrophobicContact CG-CH2 3.91Å; M287-W487 HydrophobicContact CG-CZ2 4.24Å; M287-W487 HydrophobicContact CG-CZ3 3.67Å; M287-W487 HydrophobicContact SD-CZ3 4.34Å
288	G	83.4	Confident	78.6	Confident	36 Å²	36	61.1 Å²	61.1	37%	0.371	34%	0.34	S	S	.	.	H	α-helix	trans	-65.4	-24.4	-178.5	0	0	0	0	0	114.1	L284 V285 W294	L284-G288 PolarHBondContact O-N 3.46Å; V285-G288 PolarHBondContact O-N 2.89Å; V285-G288 VanDerWaalsContact O-N 3.17Å; G288-W294 PolarHBondContact O-NE1 3.49Å
289	L	85.6	Confident	80.8	Confident	137 Å²	137	56 Å²	56	72%	0.717	32%	0.316	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.9	-4.3	175.4	-68.2	169.7	0	0	0	113.4	V285 M287 V291	V285-L289 HydrophobicContact CG1-CD1 3.87Å; V285-L289 WeakPolarHBondContact O-CG 3.5Å; V285-L289 PolarHBondContact O-N 3.17Å; M287-L289 PolarHBondContact O-N 3.42Å; L289-V291 PolarHBondContact O-N 3.02Å
290	S	88.1	Confident	83.2	Confident	9 Å²	9	53.4 Å²	53.4	6%	0.063	29%	0.288	C	S	.	.			trans	-73.8	112.2	-177.6	-179.2	0	0	0	0	112.3	S286 M287 P292 L293 W294	S286-S290 PolarHBondContact O-N 2.85Å; M287-S290 WeakPolarHBondContact O-CB 3.38Å; M287-S290 PolarHBondContact O-N 3.13Å; M287-S290 VanDerWaalsContact O-N 3.1Å; S290-P292 WeakPolarHBondContact OG-CD 3.44Å; S290-L293 PolarHBondContact O-N 3.22Å; S290-W294 PolarHBondContact O-N 3.48Å
291	V	90.6	Very high	85.4	Confident	81 Å²	81	45.2 Å²	45.2	49%	0.491	26%	0.26	S	S	.	.	H	α-helix	trans	-59.5	-43.3	176.8	176.8	0	0	0	0	112.7	L289 L293 W294 T295 F479	L289-V291 PolarHBondContact O-N 3.02Å; V291-L293 VanDerWaalsContact C-N 3.28Å; V291-L293 PolarHBondContact O-N 3.42Å; V291-W294 PolarHBondContact O-N 2.95Å; V291-T295 WeakPolarHBondContact O-CB 3.3Å; V291-T295 PolarHBondContact O-N 3.15Å; V291-T295 PolarHBondContact O-OG1 2.82Å; V291-F479 HydrophobicContact CG1-CB 4.09Å; V291-F479 HydrophobicContact CG1-CD1 3.99Å; V291-F479 HydrophobicContact CG1-CG 4.23Å
292	P	88.7	Confident	87.3	Confident	14 Å²	14	42.9 Å²	42.9	9%	0.091	24%	0.244	C	C	.	.	H	α-helix	trans	-60.8	-34.8	176.7	-28.1	38.6	0	0	0	113.6	S290 T295 I296 N481	S290-P292 WeakPolarHBondContact OG-CD 3.44Å; P292-T295 WeakPolarHBondContact O-CB 3.39Å; P292-T295 PolarHBondContact O-N 3Å; P292-I296 WeakPolarHBondContact O-CG1 3.43Å; P292-I296 PolarHBondContact O-N 3.47Å; P292-I296 VanDerWaalsContact O-N 3.07Å; P292-N481 HydrophobicContact CB-CB 4.31Å; P292-N481 HydrophobicContact CG-CB 4.16Å
293	L	89.8	Confident	88.5	Confident	6 Å²	6	40.3 Å²	40.3	3%	0.031	23%	0.231	C	C	.	.	H	α-helix	trans	-66.5	-48.9	177.6	178.7	60	0	0	0	111.2	M287 S290 V291 T295 I296 I297 I419 L427 T431	M287-L293 HydrophobicContact CB-CD2 4.4Å; M287-L293 WeakPolarHBondContact O-CD2 3.21Å; S290-L293 PolarHBondContact O-N 3.22Å; V291-L293 VanDerWaalsContact C-N 3.28Å; V291-L293 PolarHBondContact O-N 3.42Å; L293-T295 PolarHBondContact O-N 3.21Å; L293-I296 PolarHBondContact O-N 2.96Å; L293-I296 VanDerWaalsContact O-N 3.17Å; L293-I297 HydrophobicContact CD1-CD1 4.25Å; L293-I297 HydrophobicContact CD1-CG1 4.49Å; L293-I297 HydrophobicContact CG-CD1 4.01Å; L293-I297 WeakPolarHBondContact O-CG1 3.4Å; L293-I297 PolarHBondContact O-N 3.38Å; L293-I419 HydrophobicContact CB-CD1 4.42Å; L293-I419 HydrophobicContact CD1-CD1 4.22Å; L293-L427 HydrophobicContact CD1-CD1 4.36Å; L293-L427 HydrophobicContact CD1-CD2 3.78Å; L293-L427 HydrophobicContact CD2-CD2 3.98Å; L293-T431 HydrophobicContact CD1-CG2 4.45Å
294	W	92.5	Very high	89.4	Confident	114 Å²	114	39.3 Å²	39.3	43%	0.432	23%	0.225	S	C	.	.	H	α-helix	trans	-62.3	-34.2	176	-79.2	108.4	0	0	0	112.7	G288 S290 V291 I297 V298 F434	G288-W294 PolarHBondContact O-NE1 3.49Å; S290-W294 PolarHBondContact O-N 3.48Å; V291-W294 PolarHBondContact O-N 2.95Å; W294-I297 HydrophobicContact CE3-CB 4.45Å; W294-I297 HydrophobicContact CE3-CD1 4.19Å; W294-I297 HydrophobicContact CE3-CG2 4.36Å; W294-I297 HydrophobicContact CZ3-CD1 4.42Å; W294-I297 HydrophobicContact CZ3-CG2 4.4Å; W294-I297 PolarHBondContact O-N 2.71Å; W294-V298 WeakPolarHBondContact O-CB 3.37Å; W294-V298 VanDerWaalsContact O-CG2 3.31Å; W294-V298 WeakPolarHBondContact O-CG2 3.37Å; W294-V298 PolarHBondContact O-N 3.39Å; W294-F434 HydrophobicContact CH2-CZ 4.4Å
295	T	93.4	Very high	90.1	Very high	5 Å²	5	35.9 Å²	35.9	3%	0.031	21%	0.205	C	C	.	.	H	α-helix	trans	-61.2	-46.1	174.4	-56.8	0	0	0	0	111	V291 P292 L293 T299 I475 Y476 F479	V291-T295 WeakPolarHBondContact O-CB 3.3Å; V291-T295 PolarHBondContact O-N 3.15Å; V291-T295 PolarHBondContact O-OG1 2.82Å; P292-T295 WeakPolarHBondContact O-CB 3.39Å; P292-T295 PolarHBondContact O-N 3Å; L293-T295 PolarHBondContact O-N 3.21Å; T295-T299 VanDerWaalsContact O-CB 3.26Å; T295-T299 WeakPolarHBondContact O-CB 3.34Å; T295-T299 PolarHBondContact O-N 3Å; T295-T299 PolarHBondContact O-OG1 3.33Å; T295-I475 HydrophobicContact CG2-CG2 4.17Å; T295-Y476 HydrophobicContact CG2-CD2 3.81Å; T295-Y476 HydrophobicContact CG2-CG 4.43Å; T295-F479 HydrophobicContact CG2-CB 4.07Å; T295-F479 VanDerWaalsContact OG1-CB 3.22Å; T295-F479 WeakPolarHBondContact OG1-CB 3.38Å
296	I	92.6	Very high	90.7	Very high	1 Å²	1	31.1 Å²	31.1	1%	0.005	18%	0.176	C	C	.	.	H	α-helix	trans	-60.8	-47.8	175.5	-65.9	164.4	0	0	0	110.6	P292 L293 T299 Q300 V412 N415 I419 T431 Y476	P292-I296 WeakPolarHBondContact O-CG1 3.43Å; P292-I296 PolarHBondContact O-N 3.47Å; P292-I296 VanDerWaalsContact O-N 3.07Å; L293-I296 PolarHBondContact O-N 2.96Å; L293-I296 VanDerWaalsContact O-N 3.17Å; I296-T299 PolarHBondContact O-N 2.87Å; I296-Q300 VanDerWaalsContact O-CB 3.23Å; I296-Q300 WeakPolarHBondContact O-CB 3.46Å; I296-Q300 PolarHBondContact O-N 2.96Å; I296-V412 HydrophobicContact CB-CG2 4.39Å; I296-V412 HydrophobicContact CG2-CG2 3.93Å; I296-N415 HydrophobicContact CD1-CB 4.06Å; I296-N415 WeakPolarHBondContact CD1-ND2 3.5Å; I296-N415 HydrophobicContact CG1-CB 4.23Å; I296-N415 WeakPolarHBondContact CG1-ND2 3.26Å; I296-I419 HydrophobicContact CD1-CD1 3.57Å; I296-I419 HydrophobicContact CD1-CG1 4.08Å; I296-I419 HydrophobicContact CD1-CG2 4.26Å; I296-T431 HydrophobicContact CG2-CG2 4.22Å; I296-Y476 HydrophobicContact CG1-CE2 4.41Å
297	I	93.8	Very high	91.1	Very high	3 Å²	3	31.6 Å²	31.6	2%	0.015	17%	0.171	C	C	.	.	H	α-helix	trans	-58.4	-52.8	-178.9	-68.6	168.1	0	0	0	110.9	L293 W294 T299 Q300 M301 I430 T431 F434	L293-I297 HydrophobicContact CD1-CD1 4.25Å; L293-I297 HydrophobicContact CD1-CG1 4.49Å; L293-I297 HydrophobicContact CG-CD1 4.01Å; L293-I297 WeakPolarHBondContact O-CG1 3.4Å; L293-I297 PolarHBondContact O-N 3.38Å; W294-I297 HydrophobicContact CE3-CB 4.45Å; W294-I297 HydrophobicContact CE3-CD1 4.19Å; W294-I297 HydrophobicContact CE3-CG2 4.36Å; W294-I297 HydrophobicContact CZ3-CD1 4.42Å; W294-I297 HydrophobicContact CZ3-CG2 4.4Å; W294-I297 PolarHBondContact O-N 2.71Å; I297-T299 PolarHBondContact O-N 2.98Å; I297-Q300 PolarHBondContact O-N 3.27Å; I297-M301 HydrophobicContact CG2-SD 4.11Å; I297-M301 VanDerWaalsContact O-CG 3.3Å; I297-M301 WeakPolarHBondContact O-CG 3.49Å; I297-M301 PolarHBondContact O-N 3.09Å; I297-I430 HydrophobicContact CD1-CG2 3.95Å; I297-T431 HydrophobicContact CG1-CG2 3.83Å; I297-F434 HydrophobicContact CG2-CB 3.55Å; I297-F434 HydrophobicContact CG2-CD1 4.5Å; I297-F434 HydrophobicContact CG2-CD2 4.23Å; I297-F434 HydrophobicContact CG2-CG 3.86Å
298	V	94.9	Very high	91.5	Very high	51 Å²	51	32 Å²	32	31%	0.309	17%	0.172	S	C	.	.	H	α-helix	trans	-63.4	-45.1	-178.1	172.2	0	0	0	0	110.9	W294 Q300 M301 C302 I475	W294-V298 WeakPolarHBondContact O-CB 3.37Å; W294-V298 VanDerWaalsContact O-CG2 3.31Å; W294-V298 WeakPolarHBondContact O-CG2 3.37Å; W294-V298 PolarHBondContact O-N 3.39Å; V298-Q300 VanDerWaalsContact C-N 3.34Å; V298-Q300 PolarHBondContact O-N 2.98Å; V298-M301 WeakPolarHBondContact O-CB 3.39Å; V298-M301 PolarHBondContact O-N 3.44Å; V298-C302 PolarHBondContact O-N 2.81Å; V298-C302 PolarHBondContact O-SG 3.17Å; V298-I475 HydrophobicContact CG1-CD1 3.88Å
299	T	94.6	Very high	91.9	Very high	0 Å²	0	30.5 Å²	30.5	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-66	-36.7	179.6	-61.7	0	0	0	0	112.2	T295 I296 I297 C302 S303 T370 L374 V412 G472 Y476	T295-T299 VanDerWaalsContact O-CB 3.26Å; T295-T299 WeakPolarHBondContact O-CB 3.34Å; T295-T299 PolarHBondContact O-N 3Å; T295-T299 PolarHBondContact O-OG1 3.33Å; I296-T299 PolarHBondContact O-N 2.87Å; I297-T299 PolarHBondContact O-N 2.98Å; T299-C302 WeakPolarHBondContact O-CB 3.14Å; T299-C302 PolarHBondContact O-N 3.05Å; T299-S303 PolarHBondContact O-N 3.33Å; T299-T370 HydrophobicContact CG2-CG2 3.63Å; T299-L374 HydrophobicContact CG2-CD1 3.52Å; T299-V412 HydrophobicContact CG2-CB 4.21Å; T299-V412 HydrophobicContact CG2-CG1 4.49Å; T299-V412 HydrophobicContact CG2-CG2 3.97Å; T299-G472 PolarHBondContact OG1-O 3.08Å; T299-G472 VanDerWaalsContact OG1-O 3.09Å; T299-Y476 HydrophobicContact CG2-CD2 3.84Å; T299-Y476 HydrophobicContact CG2-CG 4.07Å; T299-Y476 WeakPolarHBondContact OG1-CB 3.35Å
300	Q	93.8	Very high	92.1	Very high	2 Å²	2	24.4 Å²	24.4	1%	0.009	12%	0.124	C	C	.	.	H	α-helix	trans	-67.4	-39.1	174.1	-174.3	170.6	-9.2	0	0	111.7	I296 I297 V298 C302 S303 N304 V412 Y413	I296-Q300 VanDerWaalsContact O-CB 3.23Å; I296-Q300 WeakPolarHBondContact O-CB 3.46Å; I296-Q300 PolarHBondContact O-N 2.96Å; I297-Q300 PolarHBondContact O-N 3.27Å; V298-Q300 VanDerWaalsContact C-N 3.34Å; V298-Q300 PolarHBondContact O-N 2.98Å; Q300-C302 VanDerWaalsContact C-N 3.33Å; Q300-C302 PolarHBondContact O-N 3.35Å; Q300-S303 PolarHBondContact O-N 3.22Å; Q300-N304 WeakPolarHBondContact O-CB 3.46Å; Q300-N304 PolarHBondContact O-N 3.08Å; Q300-V412 HydrophobicContact CB-CG2 4.4Å; Q300-Y413 HydrophobicContact CG-CD1 4.45Å; Q300-Y413 HydrophobicContact CG-CE1 3.84Å; Q300-Y413 VanDerWaalsContact NE2-CE1 3.31Å
301	M	94.4	Very high	92	Very high	49 Å²	49	24.3 Å²	24.3	24%	0.241	12%	0.122	C	C	.	.	H	α-helix	trans	-59.2	-43.6	171.1	-71.7	175.1	67.6	0	0	111.6	I297 V298 N304 W305 F434 I437 P438	I297-M301 HydrophobicContact CG2-SD 4.11Å; I297-M301 VanDerWaalsContact O-CG 3.3Å; I297-M301 WeakPolarHBondContact O-CG 3.49Å; I297-M301 PolarHBondContact O-N 3.09Å; V298-M301 WeakPolarHBondContact O-CB 3.39Å; V298-M301 PolarHBondContact O-N 3.44Å; M301-N304 PolarHBondContact O-N 3.42Å; M301-W305 PolarHBondContact O-N 2.58Å; M301-F434 HydrophobicContact CG-CB 4.39Å; M301-F434 WeakPolarHBondContact CG-O 3Å; M301-F434 HydrophobicContact SD-CB 4.06Å; M301-I437 HydrophobicContact CE-CB 4.19Å; M301-I437 HydrophobicContact CE-CD1 4.16Å; M301-I437 HydrophobicContact CE-CG2 4.33Å; M301-P438 HydrophobicContact CB-CG 4.11Å; M301-P438 VanDerWaalsContact O-CG 3.22Å; M301-P438 WeakPolarHBondContact O-CG 3.29Å
302	C	94.6	Very high	91.8	Very high	15 Å²	15	21 Å²	21	10%	0.101	10%	0.102	C	C	.	.	H	α-helix	trans	-60.4	-47.6	175.7	-67.4	0	0	0	0	111.8	V298 T299 Q300 N304 W305 L374 I468 N469 G472	V298-C302 PolarHBondContact O-N 2.81Å; V298-C302 PolarHBondContact O-SG 3.17Å; T299-C302 WeakPolarHBondContact O-CB 3.14Å; T299-C302 PolarHBondContact O-N 3.05Å; Q300-C302 VanDerWaalsContact C-N 3.33Å; Q300-C302 PolarHBondContact O-N 3.35Å; C302-N304 VanDerWaalsContact C-N 3.35Å; C302-N304 PolarHBondContact O-N 3.47Å; C302-W305 WeakPolarHBondContact O-CB 3.48Å; C302-W305 PolarHBondContact O-N 3.26Å; C302-L374 HydrophobicContact CB-CD2 4.43Å; C302-I468 HydrophobicContact CB-CG2 3.86Å; C302-I468 WeakPolarHBondContact CB-O 3.28Å; C302-I468 PolarHBondContact SG-O 2.74Å; C302-N469 PolarHBondContact O-OD1 3.31Å; C302-G472 VanDerWaalsContact SG-CA 3.53Å
303	S	92.8	Very high	91.8	Very high	16 Å²	16	20.5 Å²	20.5	11%	0.112	10%	0.1	C	C	.	.	H	α-helix	trans	-59.5	-45.1	177.1	-174.3	0	0	0	0	111.8	T299 Q300 W305 S306 F307	T299-S303 PolarHBondContact O-N 3.33Å; Q300-S303 PolarHBondContact O-N 3.22Å; S303-W305 VanDerWaalsContact C-N 3.31Å; S303-W305 PolarHBondContact O-N 2.92Å; S303-S306 PolarHBondContact O-N 3.48Å; S303-F307 PolarHBondContact O-N 2.93Å
304	N	92.3	Very high	91.7	Very high	9 Å²	9	20.4 Å²	20.4	5%	0.048	10%	0.099	C	C	.	.	H	α-helix	trans	-68.1	-27.7	179.3	-83.9	-15.7	0	0	0	113.6	Q300 M301 C302 F307 Y308 Y413 G435 P438	Q300-N304 WeakPolarHBondContact O-CB 3.46Å; Q300-N304 PolarHBondContact O-N 3.08Å; M301-N304 PolarHBondContact O-N 3.42Å; C302-N304 VanDerWaalsContact C-N 3.35Å; C302-N304 PolarHBondContact O-N 3.47Å; N304-F307 PolarHBondContact O-N 3.34Å; N304-Y308 HydrophobicContact CB-CD2 4.06Å; N304-Y308 HydrophobicContact CB-CE2 3.85Å; N304-Y308 WeakPolarHBondContact O-CB 3.34Å; N304-Y308 WeakPolarHBondContact O-CD2 3.45Å; N304-Y308 PolarHBondContact O-N 3Å; N304-Y413 PolarHBondContact OD1-OH 2.91Å; N304-G435 VanDerWaalsContact CB-O 3.25Å; N304-G435 WeakPolarHBondContact CB-O 3.32Å; N304-G435 PolarHBondContact ND2-O 3.38Å; N304-P438 HydrophobicContact CB-CG 4.3Å
305	W	94.1	Very high	91.3	Very high	31 Å²	31	15.1 Å²	15.1	12%	0.117	8%	0.079	C	C	.	.	H	α-helix	trans	-56.4	-53.4	174.1	-178.7	-79.5	0	0	0	111.4	M301 C302 S303 T309 P438 V441 A442 V445 V464 I468	M301-W305 PolarHBondContact O-N 2.58Å; C302-W305 WeakPolarHBondContact O-CB 3.48Å; C302-W305 PolarHBondContact O-N 3.26Å; S303-W305 VanDerWaalsContact C-N 3.31Å; S303-W305 PolarHBondContact O-N 2.92Å; W305-T309 WeakPolarHBondContact O-CB 3.29Å; W305-T309 PolarHBondContact O-N 3.32Å; W305-T309 PolarHBondContact O-OG1 2.96Å; W305-P438 HydrophobicContact CB-CB 3.97Å; W305-P438 HydrophobicContact CE3-CB 3.92Å; W305-V441 HydrophobicContact CH2-CB 4.24Å; W305-V441 HydrophobicContact CH2-CG1 3.73Å; W305-V441 HydrophobicContact CZ3-CB 3.8Å; W305-V441 HydrophobicContact CZ3-CG1 3.66Å; W305-A442 HydrophobicContact CD2-CB 4.1Å; W305-A442 HydrophobicContact CE3-CB 4.3Å; W305-A442 HydrophobicContact CH2-CB 4.32Å; W305-A442 HydrophobicContact CZ2-CB 4.12Å; W305-A442 HydrophobicContact CZ3-CB 4.41Å; W305-V445 HydrophobicContact CH2-CB 4.28Å; W305-V445 HydrophobicContact CH2-CG2 4.07Å; W305-V445 HydrophobicContact CZ2-CB 4.34Å; W305-V445 HydrophobicContact CZ2-CG1 4.29Å; W305-V464 HydrophobicContact CZ2-CG1 4.13Å; W305-I468 HydrophobicContact CB-CG2 4.03Å; W305-I468 HydrophobicContact CD2-CD1 3.52Å; W305-I468 VanDerWaalsContact CE2-CD1 3.44Å; W305-I468 HydrophobicContact CE3-CD1 4.02Å; W305-I468 HydrophobicContact CG-CD1 3.83Å; W305-I468 HydrophobicContact CG-CG2 4.14Å; W305-I468 HydrophobicContact CH2-CD1 4.34Å; W305-I468 HydrophobicContact CZ2-CD1 3.9Å; W305-I468 HydrophobicContact CZ3-CD1 4.4Å
306	S	91.4	Very high	91	Very high	9 Å²	9	15.5 Å²	15.5	6%	0.063	8%	0.081	C	C	.	.	H	α-helix	trans	-65.5	-41.1	179.9	-67	0	0	0	0	111.9	S303 L310 N469	S303-S306 PolarHBondContact O-N 3.48Å; S306-L310 WeakPolarHBondContact O-CG 3.45Å; S306-L310 PolarHBondContact O-N 3.09Å; S306-L310 VanDerWaalsContact O-N 3.11Å; S306-N469 PolarHBondContact OG-ND2 3.47Å; S306-N469 PolarHBondContact OG-OD1 2.92Å
307	F	89.9	Confident	90.7	Very high	70 Å²	70	15.7 Å²	15.7	31%	0.307	8%	0.082	S	C	.	.	H	α-helix	trans	-59.8	-51.1	177.4	180	-100.9	0	0	0	112.1	S303 N304 L310 L311 Y337	S303-F307 PolarHBondContact O-N 2.93Å; N304-F307 PolarHBondContact O-N 3.34Å; F307-L310 PolarHBondContact O-N 3.04Å; F307-L311 HydrophobicContact CE1-CD2 4.06Å; F307-L311 HydrophobicContact CZ-CD2 4.48Å; F307-L311 VanDerWaalsContact O-CB 3.3Å; F307-L311 WeakPolarHBondContact O-CB 3.48Å; F307-L311 PolarHBondContact O-N 3.34Å; F307-Y337 HydrophobicContact CD2-CE1 4.14Å; F307-Y337 AromaticContact CE2-CD1 3.79Å; F307-Y337 HydrophobicContact CE2-CD1 3.79Å; F307-Y337 AromaticContact CE2-CE1 3.66Å; F307-Y337 HydrophobicContact CE2-CE1 3.66Å; F307-Y337 HydrophobicContact CZ-CD1 4.4Å; F307-Y337 HydrophobicContact CZ-CE1 4.26Å
308	Y	90.2	Very high	90.3	Very high	13 Å²	13	15.6 Å²	15.6	5%	0.051	8%	0.082	C	C	.	.	H	α-helix	trans	-70.9	-37.2	-179.3	-67.3	-47.2	0	0	0	112.9	F117 N304 L310 L311 T312 P438	F117-Y308 HydrophobicContact CE1-CD1 4.09Å; F117-Y308 AromaticContact CE1-CE1 3.78Å; F117-Y308 HydrophobicContact CE1-CE1 3.78Å; F117-Y308 HydrophobicContact CE1-CE2 4.3Å; F117-Y308 AromaticContact CE1-CZ 3.89Å; F117-Y308 AromaticContact CZ-CD1 3.71Å; F117-Y308 HydrophobicContact CZ-CD1 3.71Å; F117-Y308 AromaticContact CZ-CE1 3.82Å; F117-Y308 HydrophobicContact CZ-CE1 3.82Å; F117-Y308 HydrophobicContact CZ-CG 4.2Å; N304-Y308 HydrophobicContact CB-CD2 4.06Å; N304-Y308 HydrophobicContact CB-CE2 3.85Å; N304-Y308 WeakPolarHBondContact O-CB 3.34Å; N304-Y308 WeakPolarHBondContact O-CD2 3.45Å; N304-Y308 PolarHBondContact O-N 3Å; Y308-L310 VanDerWaalsContact C-N 3.31Å; Y308-L310 PolarHBondContact O-N 3.29Å; Y308-L311 HydrophobicContact CD1-CD2 4.19Å; Y308-L311 PolarHBondContact O-N 3.47Å; Y308-T312 PolarHBondContact O-N 3.23Å; Y308-T312 PolarHBondContact O-OG1 2.96Å; Y308-P438 HydrophobicContact CD2-CB 4.35Å
309	T	91.3	Very high	89.7	Confident	5 Å²	5	14.1 Å²	14.1	3%	0.031	7%	0.072	C	C	.	.	H	α-helix	trans	-55.4	-48.7	174.6	-56.1	0	0	0	0	110.8	W305 L311 S313 A442 V461	W305-T309 WeakPolarHBondContact O-CB 3.29Å; W305-T309 PolarHBondContact O-N 3.32Å; W305-T309 PolarHBondContact O-OG1 2.96Å; T309-L311 VanDerWaalsContact C-N 3.35Å; T309-S313 VanDerWaalsContact O-CB 3.22Å; T309-S313 WeakPolarHBondContact O-CB 3.14Å; T309-S313 PolarHBondContact O-N 2.9Å; T309-S313 PolarHBondContact O-OG 3.39Å; T309-A442 WeakPolarHBondContact OG1-CB 3.41Å; T309-V461 HydrophobicContact CG2-CG1 3.81Å
310	L	90.2	Very high	88.9	Confident	9 Å²	9	15.2 Å²	15.2	5%	0.047	8%	0.078	C	C	.	.	H	α-helix	trans	-71.4	-30.6	177	-64.1	177.7	0	0	0	111.5	S306 F307 Y308 L314 Y337 L381 L398 T402 F462	S306-L310 WeakPolarHBondContact O-CG 3.45Å; S306-L310 PolarHBondContact O-N 3.09Å; S306-L310 VanDerWaalsContact O-N 3.11Å; F307-L310 PolarHBondContact O-N 3.04Å; Y308-L310 VanDerWaalsContact C-N 3.31Å; Y308-L310 PolarHBondContact O-N 3.29Å; L310-L314 HydrophobicContact CD2-CD1 4.39Å; L310-L314 WeakPolarHBondContact O-CB 3.47Å; L310-L314 PolarHBondContact O-N 3.48Å; L310-Y337 PolarHBondContact O-OH 3.34Å; L310-L381 HydrophobicContact CD1-CD2 4.33Å; L310-L381 HydrophobicContact CD2-CD2 4.28Å; L310-L398 HydrophobicContact CD2-CD2 3.97Å; L310-T402 VanDerWaalsContact CD1-OG1 3.3Å; L310-T402 WeakPolarHBondContact CD1-OG1 3.38Å; L310-F462 HydrophobicContact CD2-CE1 4.18Å
311	L	86.1	Confident	88.4	Confident	7 Å²	7	15.1 Å²	15.1	4%	0.037	8%	0.077	C	C	.	.	H	α-helix	trans	-69.6	-40.4	-179.8	-171.2	69.4	0	0	0	112.2	V53 S56 F307 Y308 T309 Y337	V53-L311 HydrophobicContact CG1-CD1 3.96Å; V53-L311 HydrophobicContact CG1-CD2 4.34Å; V53-L311 HydrophobicContact CG1-CG 4.26Å; S56-L311 PolarHBondContact OG-O 2.88Å; F307-L311 HydrophobicContact CE1-CD2 4.06Å; F307-L311 HydrophobicContact CZ-CD2 4.48Å; F307-L311 VanDerWaalsContact O-CB 3.3Å; F307-L311 WeakPolarHBondContact O-CB 3.48Å; F307-L311 PolarHBondContact O-N 3.34Å; Y308-L311 HydrophobicContact CD1-CD2 4.19Å; Y308-L311 PolarHBondContact O-N 3.47Å; T309-L311 VanDerWaalsContact C-N 3.35Å; L311-Y337 WeakPolarHBondContact CA-OH 3.29Å; L311-Y337 HydrophobicContact CD1-CE1 3.9Å; L311-Y337 HydrophobicContact CD1-CE2 4.06Å; L311-Y337 PolarHBondContact N-OH 3.29Å
312	T	86.9	Confident	87.6	Confident	11 Å²	11	12.9 Å²	12.9	7%	0.067	7%	0.066	C	C	.	.	H	α-helix	trans	-88.7	-38.5	-175.3	58.2	0	0	0	0	112.6	S56 F117 Y308 P443	S56-T312 VanDerWaalsContact CB-O 3.22Å; S56-T312 WeakPolarHBondContact CB-O 3.36Å; F117-T312 HydrophobicContact CE2-CG2 4.4Å; Y308-T312 PolarHBondContact O-N 3.23Å; Y308-T312 PolarHBondContact O-OG1 2.96Å; T312-P443 HydrophobicContact CG2-CG 3.97Å
313	S	87.7	Confident	86.9	Confident	5 Å²	5	15.6 Å²	15.6	4%	0.035	8%	0.077	C	C	.	.	H	α-helix	trans	-110.5	-9.8	-164	-43.6	0	0	0	0	113.3	T309 T316 Y317 W458	T309-S313 VanDerWaalsContact O-CB 3.22Å; T309-S313 WeakPolarHBondContact O-CB 3.14Å; T309-S313 PolarHBondContact O-N 2.9Å; T309-S313 PolarHBondContact O-OG 3.39Å; S313-T316 PolarHBondContact O-N 3.14Å; S313-Y317 PolarHBondContact O-N 3.48Å; S313-W458 VanDerWaalsContact O-CH2 3.3Å; S313-W458 WeakPolarHBondContact O-CH2 3.06Å
314	L	87.4	Confident	86.2	Confident	4 Å²	4	16.7 Å²	16.7	2%	0.021	8%	0.081	C	C	.	.	H	α-helix	trans	-60.1	-43.3	176.9	-177.3	70.2	0	0	0	113.1	L310 T316 Y317 M318 P336 L398	L310-L314 HydrophobicContact CD2-CD1 4.39Å; L310-L314 WeakPolarHBondContact O-CB 3.47Å; L310-L314 PolarHBondContact O-N 3.48Å; L314-T316 VanDerWaalsContact C-N 3.29Å; L314-T316 PolarHBondContact O-N 3.28Å; L314-Y317 WeakPolarHBondContact O-CB 3.48Å; L314-Y317 PolarHBondContact O-N 2.73Å; L314-M318 HydrophobicContact CD1-CE 3.68Å; L314-M318 HydrophobicContact CD1-CG 4.45Å; L314-M318 HydrophobicContact CG-CE 4.18Å; L314-M318 HydrophobicContact CG-CG 4.39Å; L314-M318 VanDerWaalsContact O-CG 3.31Å; L314-M318 WeakPolarHBondContact O-CG 3.27Å; L314-M318 PolarHBondContact O-N 3.06Å; L314-P336 HydrophobicContact CD2-CG 4.16Å; L314-L398 HydrophobicContact CD1-CD1 3.81Å; L314-L398 HydrophobicContact CD1-CD2 4.31Å; L314-L398 HydrophobicContact CD1-CG 4.48Å
315	P	85.8	Confident	85.6	Confident	2 Å²	2	19.1 Å²	19.1	1%	0.013	9%	0.094	C	C	.	.	H	α-helix	trans	-61.9	-38.7	177.7	-23.7	35.9	0	0	0	112.4	V57 V60 M318 N319 N329	V57-P315 HydrophobicContact CG2-CB 4.07Å; V57-P315 HydrophobicContact CG2-CG 3.82Å; V60-P315 HydrophobicContact CG2-CB 4.21Å; P315-M318 PolarHBondContact O-N 2.87Å; P315-N319 PolarHBondContact O-N 3.03Å; P315-N319 VanDerWaalsContact O-N 3.14Å; P315-N329 WeakPolarHBondContact CA-OD1 3.49Å; P315-N329 PolarHBondContact O-ND2 3.3Å
316	T	85.7	Confident	84.8	Confident	13 Å²	13	17.9 Å²	17.9	8%	0.08	9%	0.089	C	C	.	.	H	α-helix	trans	-63.2	-44.6	174.8	-49.2	0	0	0	0	111.2	S313 L314 M318 N319 D320 W458	S313-T316 PolarHBondContact O-N 3.14Å; L314-T316 VanDerWaalsContact C-N 3.29Å; L314-T316 PolarHBondContact O-N 3.28Å; T316-M318 PolarHBondContact O-N 3.4Å; T316-N319 PolarHBondContact O-N 2.95Å; T316-D320 WeakPolarHBondContact CG2-OD2 3.46Å; T316-D320 WeakPolarHBondContact O-CB 3.35Å; T316-D320 PolarHBondContact O-N 2.89Å; T316-W458 HydrophobicContact CG2-CZ2 4.22Å
317	Y	86.9	Confident	84.1	Confident	5 Å²	5	21.6 Å²	21.6	2%	0.02	11%	0.105	C	C	.	.	H	α-helix	trans	-60.1	-46	176	177.7	-103.8	0	0	0	112.8	S313 L314 N319 I321 L322 T394 L398 W458 F462	S313-Y317 PolarHBondContact O-N 3.48Å; L314-Y317 WeakPolarHBondContact O-CB 3.48Å; L314-Y317 PolarHBondContact O-N 2.73Å; Y317-N319 PolarHBondContact O-N 3.4Å; Y317-I321 HydrophobicContact CD2-CB 4Å; Y317-I321 HydrophobicContact CD2-CG1 3.77Å; Y317-I321 HydrophobicContact CD2-CG2 4.46Å; Y317-I321 HydrophobicContact CE2-CB 3.86Å; Y317-I321 HydrophobicContact CE2-CG1 3.83Å; Y317-I321 HydrophobicContact CE2-CG2 3.81Å; Y317-I321 WeakPolarHBondContact O-CB 3.25Å; Y317-I321 PolarHBondContact O-N 2.93Å; Y317-L322 HydrophobicContact CD1-CD1 4.44Å; Y317-L322 HydrophobicContact CE1-CD1 3.95Å; Y317-L322 HydrophobicContact CE1-CG 4.37Å; Y317-T394 HydrophobicContact CE1-CG2 3.7Å; Y317-L398 HydrophobicContact CD1-CD1 4.12Å; Y317-L398 HydrophobicContact CE1-CD1 3.87Å; Y317-W458 HydrophobicContact CD2-CB 4.09Å; Y317-W458 AromaticContact CD2-CD2 3.44Å; Y317-W458 HydrophobicContact CD2-CD2 3.44Å; Y317-W458 VanDerWaalsContact CD2-CD2 3.44Å; Y317-W458 AromaticContact CD2-CE2 3.82Å; Y317-W458 AromaticContact CD2-CE3 3.72Å; Y317-W458 HydrophobicContact CD2-CE3 3.72Å; Y317-W458 AromaticContact CD2-CG 3.61Å; Y317-W458 HydrophobicContact CD2-CG 3.61Å; Y317-W458 HydrophobicContact CD2-CZ2 4.4Å; Y317-W458 HydrophobicContact CD2-CZ3 4.31Å; Y317-W458 HydrophobicContact CE2-CB 3.96Å; Y317-W458 HydrophobicContact CE2-CD2 4.22Å; Y317-W458 AromaticContact CE2-CG 3.96Å; Y317-W458 HydrophobicContact CE2-CG 3.96Å; Y317-W458 HydrophobicContact CG-CD2 4.31Å; Y317-W458 HydrophobicContact CG-CE3 4.28Å; Y317-W458 HydrophobicContact CG-CZ3 4.46Å; Y317-F462 HydrophobicContact CD1-CZ 4.36Å; Y317-F462 HydrophobicContact CD2-CE2 4.21Å; Y317-F462 HydrophobicContact CD2-CZ 4.07Å; Y317-F462 HydrophobicContact CE1-CE2 4.5Å; Y317-F462 HydrophobicContact CE1-CZ 4.3Å; Y317-F462 AromaticContact CE2-CE2 3.71Å; Y317-F462 HydrophobicContact CE2-CE2 3.71Å; Y317-F462 AromaticContact CE2-CZ 3.98Å; Y317-F462 HydrophobicContact CE2-CZ 3.98Å; Y317-F462 HydrophobicContact CG-CZ 4.24Å; Y317-F462 AromaticContact CZ-CE2 3.88Å
318	M	84.7	Confident	83.8	Confident	1 Å²	1	20.3 Å²	20.3	1%	0.005	11%	0.105	C	C	.	.	H	α-helix	trans	-62.3	-32.4	179.5	-70	-67.3	178.6	0	0	112.5	L314 P315 T316 L322 H323 F324 N329 V395 L398	L314-M318 HydrophobicContact CD1-CE 3.68Å; L314-M318 HydrophobicContact CD1-CG 4.45Å; L314-M318 HydrophobicContact CG-CE 4.18Å; L314-M318 HydrophobicContact CG-CG 4.39Å; L314-M318 VanDerWaalsContact O-CG 3.31Å; L314-M318 WeakPolarHBondContact O-CG 3.27Å; L314-M318 PolarHBondContact O-N 3.06Å; P315-M318 PolarHBondContact O-N 2.87Å; T316-M318 PolarHBondContact O-N 3.4Å; M318-L322 CarbonylContact O-C 3.55Å; M318-L322 WeakPolarHBondContact O-CB 3.33Å; M318-L322 HydrophobicContact SD-CD1 3.6Å; M318-L322 VanDerWaalsContact SD-CD1 3.6Å; M318-H323 PolarHBondContact O-N 2.66Å; M318-F324 HydrophobicContact CB-CD2 4.2Å; M318-F324 PolarHBondContact O-N 2.99Å; M318-F324 VanDerWaalsContact O-N 3.08Å; M318-F324 HydrophobicContact SD-CD2 3.9Å; M318-F324 HydrophobicContact SD-CE2 3.93Å; M318-N329 WeakPolarHBondContact CB-OD1 3.24Å; M318-V395 HydrophobicContact CE-CG2 3.95Å; M318-V395 HydrophobicContact SD-CG2 4.08Å; M318-L398 HydrophobicContact CE-CD1 3.67Å
319	N	82.7	Confident	83.5	Confident	20 Å²	20	19.7 Å²	19.7	11%	0.107	10%	0.103	C	C	.	.	H	α-helix	trans	-81.7	-53.8	177	-179	79.3	0	0	0	112.6	V60 P315 T316 Y317 H323	V60-N319 HydrophobicContact CG1-CB 3.54Å; V60-N319 WeakPolarHBondContact CG1-OD1 3.46Å; V60-N319 HydrophobicContact CG2-CB 4.33Å; P315-N319 PolarHBondContact O-N 3.03Å; P315-N319 VanDerWaalsContact O-N 3.14Å; T316-N319 PolarHBondContact O-N 2.95Å; Y317-N319 PolarHBondContact O-N 3.4Å; N319-H323 WeakPolarHBondContact O-CA 3.49Å; N319-H323 PolarHBondContact O-N 3.24Å; N319-H323 VanDerWaalsContact O-N 3.09Å; N319-H323 PolarHBondContact O-ND1 3.42Å; N319-H323 VanDerWaalsContact O-ND1 3.16Å
320	D	79	Confident	83.1	Confident	23 Å²	23	19.4 Å²	19.4	12%	0.123	10%	0.101	C	C	.	.	H	α-helix	trans	-73.8	-34.7	-169.1	-70.5	9.5	0	0	0	112.4	T316 H323 H453	T316-D320 WeakPolarHBondContact CG2-OD2 3.46Å; T316-D320 WeakPolarHBondContact O-CB 3.35Å; T316-D320 PolarHBondContact O-N 2.89Å; D320-H323 PolarHBondContact O-CE1 3.25Å; D320-H453 IonicContact OD2-CE1 3.91Å; D320-H453 IonicContact OD2-ND1 2.66Å; D320-H453 PolarHBondContact OD2-ND1 3.27Å
321	I	82.1	Confident	82.9	Confident	0 Å²	0	25.1 Å²	25.1	0%	0	13%	0.126	C	C	.	.	T	Hydrogen-bonded Turn	trans	-101.8	-44.2	-174.7	-62.7	-60.3	0	0	0	112.2	A79 C80 Y317 M455 W458	A79-I321 HydrophobicContact CB-CD1 4.45Å; C80-I321 WeakPolarHBondContact CB-O 3.27Å; C80-I321 PolarHBondContact N-O 3.41Å; Y317-I321 HydrophobicContact CD2-CB 4Å; Y317-I321 HydrophobicContact CD2-CG1 3.77Å; Y317-I321 HydrophobicContact CD2-CG2 4.46Å; Y317-I321 HydrophobicContact CE2-CB 3.86Å; Y317-I321 HydrophobicContact CE2-CG1 3.83Å; Y317-I321 HydrophobicContact CE2-CG2 3.81Å; Y317-I321 WeakPolarHBondContact O-CB 3.25Å; Y317-I321 PolarHBondContact O-N 2.93Å; I321-M455 HydrophobicContact CD1-CG 4.26Å; I321-M455 HydrophobicContact CD1-SD 4.42Å; I321-M455 HydrophobicContact CG2-CE 4.29Å; I321-M455 HydrophobicContact CG2-CG 4.12Å; I321-M455 HydrophobicContact CG2-SD 3.22Å; I321-M455 WeakPolarHBondContact CG2-SD 3.32Å; I321-W458 HydrophobicContact CG1-CG 4.13Å
322	L	78.6	Confident	83	Confident	2 Å²	2	26.5 Å²	26.5	1%	0.01	13%	0.133	C	C	.	.	T	Hydrogen-bonded Turn	trans	-95.2	-11.4	-176.3	-64	173.6	0	0	0	113	Y317 M318 F324 H391 T394	Y317-L322 HydrophobicContact CD1-CD1 4.44Å; Y317-L322 HydrophobicContact CE1-CD1 3.95Å; Y317-L322 HydrophobicContact CE1-CG 4.37Å; M318-L322 CarbonylContact O-C 3.55Å; M318-L322 WeakPolarHBondContact O-CB 3.33Å; M318-L322 HydrophobicContact SD-CD1 3.6Å; M318-L322 VanDerWaalsContact SD-CD1 3.6Å; L322-F324 VanDerWaalsContact C-N 3.25Å; L322-F324 HydrophobicContact CB-CD2 3.68Å; L322-F324 HydrophobicContact CB-CE2 3.81Å; L322-F324 HydrophobicContact CD1-CD2 4.22Å; L322-F324 HydrophobicContact CD1-CE2 3.79Å; L322-F324 HydrophobicContact CG-CE2 4.41Å; L322-F324 PolarHBondContact O-N 3.24Å; L322-H391 PolarHBondContact O-CD2 3.44Å; L322-H391 PolarHBondContact O-NE2 3.36Å; L322-T394 HydrophobicContact CD1-CG2 3.8Å; L322-T394 HydrophobicContact CD2-CG2 4.43Å
323	H	79.3	Confident	83	Confident	72 Å²	72	26 Å²	26	33%	0.333	13%	0.13	S	C	.	.			trans	55.6	37.1	179	-56.4	-46.9	0	0	0	113.9	C80 L82 M318 N319 D320	C80-H323 PolarHBondContact O-CD2 3.07Å; C80-H323 PolarHBondContact O-NE2 3.19Å; L82-H323 HydrophobicContact CD2-CB 3.92Å; M318-H323 PolarHBondContact O-N 2.66Å; N319-H323 WeakPolarHBondContact O-CA 3.49Å; N319-H323 PolarHBondContact O-N 3.24Å; N319-H323 VanDerWaalsContact O-N 3.09Å; N319-H323 PolarHBondContact O-ND1 3.42Å; N319-H323 VanDerWaalsContact O-ND1 3.16Å; D320-H323 PolarHBondContact O-CE1 3.25Å
324	F	78.8	Confident	83	Confident	40 Å²	40	26 Å²	26	18%	0.175	13%	0.13	C	C	.	.			trans	-70.6	141.8	169.1	-75.7	-63.8	0	0	0	111.1	M318 L322 N329 L332 H391 V395	M318-F324 HydrophobicContact CB-CD2 4.2Å; M318-F324 PolarHBondContact O-N 2.99Å; M318-F324 VanDerWaalsContact O-N 3.08Å; M318-F324 HydrophobicContact SD-CD2 3.9Å; M318-F324 HydrophobicContact SD-CE2 3.93Å; L322-F324 VanDerWaalsContact C-N 3.25Å; L322-F324 HydrophobicContact CB-CD2 3.68Å; L322-F324 HydrophobicContact CB-CE2 3.81Å; L322-F324 HydrophobicContact CD1-CD2 4.22Å; L322-F324 HydrophobicContact CD1-CE2 3.79Å; L322-F324 HydrophobicContact CG-CE2 4.41Å; L322-F324 PolarHBondContact O-N 3.24Å; F324-N329 HydrophobicContact CB-CB 4.34Å; F324-L332 HydrophobicContact CD1-CD1 3.93Å; F324-L332 HydrophobicContact CD2-CD1 4.13Å; F324-L332 HydrophobicContact CE1-CD1 3.66Å; F324-L332 HydrophobicContact CE2-CD1 3.84Å; F324-L332 HydrophobicContact CG-CD1 4.16Å; F324-L332 HydrophobicContact CZ-CD1 3.58Å; F324-H391 AromaticContact CE2-CD2 3.94Å; F324-H391 HydrophobicContact CZ-CB 3.87Å; F324-H391 AromaticContact CZ-CD2 3.68Å; F324-V395 HydrophobicContact CE2-CG2 3.98Å; F324-V395 HydrophobicContact CZ-CG2 4.23Å
325	D	79.3	Confident	83.1	Confident	60 Å²	60	28.6 Å²	28.6	32%	0.321	14%	0.144	S	C	.	.			trans	-61.5	159.1	168.5	56.4	-67.9	0	0	0	111.6	Q327 S328 N329	D325-Q327 PolarHBondContact O-N 3.36Å; D325-S328 VanDerWaalsContact CG-CB 3.49Å; D325-S328 PolarHBondContact O-N 3.45Å; D325-S328 WeakPolarHBondContact OD1-CB 3.38Å; D325-S328 PolarHBondContact OD1-OG 3.38Å; D325-S328 VanDerWaalsContact OD2-CB 3.27Å; D325-S328 WeakPolarHBondContact OD2-CB 3.33Å; D325-S328 PolarHBondContact OD2-N 2.93Å; D325-S328 PolarHBondContact OD2-OG 3.19Å; D325-N329 WeakPolarHBondContact O-CB 3.36Å; D325-N329 PolarHBondContact O-N 2.93Å
326	L	76.3	Confident	83.2	Confident	5 Å²	5	28.5 Å²	28.5	3%	0.026	14%	0.143	C	C	.	.	H	α-helix	trans	-64.4	-38.5	-171.5	-164.8	63	0	0	0	113.2	V57 V60 A61 L93 C222 G330	V57-L326 HydrophobicContact CG1-CD1 4.24Å; V60-L326 HydrophobicContact CB-CD1 4.19Å; V60-L326 HydrophobicContact CG1-CD1 4.05Å; A61-L326 HydrophobicContact CB-CD1 4.39Å; A61-L326 HydrophobicContact CB-CD2 3.8Å; L93-L326 HydrophobicContact CD2-CB 4Å; L93-L326 HydrophobicContact CD2-CD1 4.03Å; L93-L326 HydrophobicContact CD2-CD2 4Å; L93-L326 HydrophobicContact CD2-CG 4.25Å; C222-L326 HydrophobicContact CB-CD2 3.21Å; C222-L326 HydrophobicContact CB-CG 4.22Å; L326-G330 PolarHBondContact O-N 2.68Å
327	Q	77.8	Confident	83.3	Confident	86 Å²	86	28.5 Å²	28.5	40%	0.402	14%	0.142	S	C	.	.	H	α-helix	trans	-65.7	-51.6	175.2	176.5	177.2	47.3	0	0	111.6	E223 D325 N329 G330 F331	E223-Q327 WeakPolarHBondContact OE2-CB 3.21Å; D325-Q327 PolarHBondContact O-N 3.36Å; Q327-N329 VanDerWaalsContact C-N 3.28Å; Q327-N329 PolarHBondContact O-N 2.97Å; Q327-G330 PolarHBondContact O-N 3.45Å; Q327-F331 PolarHBondContact O-N 3.26Å; Q327-F331 VanDerWaalsContact O-N 3.11Å
328	S	82.4	Confident	83.3	Confident	43 Å²	43	34.5 Å²	34.5	30%	0.301	17%	0.168	S	C	.	.	H	α-helix	trans	-62.8	-37.2	177.7	-59.5	0	0	0	0	111.6	D325 F331 L332	D325-S328 VanDerWaalsContact CG-CB 3.49Å; D325-S328 PolarHBondContact O-N 3.45Å; D325-S328 WeakPolarHBondContact OD1-CB 3.38Å; D325-S328 PolarHBondContact OD1-OG 3.38Å; D325-S328 VanDerWaalsContact OD2-CB 3.27Å; D325-S328 WeakPolarHBondContact OD2-CB 3.33Å; D325-S328 PolarHBondContact OD2-N 2.93Å; D325-S328 PolarHBondContact OD2-OG 3.19Å; S328-F331 PolarHBondContact O-N 3.01Å; S328-L332 VanDerWaalsContact O-CB 3.26Å; S328-L332 WeakPolarHBondContact O-CB 3.43Å; S328-L332 WeakPolarHBondContact O-CG 3.45Å; S328-L332 PolarHBondContact O-N 3.45Å
329	N	84.2	Confident	83.5	Confident	0 Å²	0	36.3 Å²	36.3	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-60.4	-47.7	175.1	-175.8	8.7	0	0	0	111.7	P315 M318 F324 D325 Q327 F331 L332 S333	P315-N329 WeakPolarHBondContact CA-OD1 3.49Å; P315-N329 PolarHBondContact O-ND2 3.3Å; M318-N329 WeakPolarHBondContact CB-OD1 3.24Å; F324-N329 HydrophobicContact CB-CB 4.34Å; D325-N329 WeakPolarHBondContact O-CB 3.36Å; D325-N329 PolarHBondContact O-N 2.93Å; Q327-N329 VanDerWaalsContact C-N 3.28Å; Q327-N329 PolarHBondContact O-N 2.97Å; N329-F331 VanDerWaalsContact C-N 3.32Å; N329-F331 PolarHBondContact O-N 3.31Å; N329-L332 PolarHBondContact O-N 2.82Å; N329-S333 WeakPolarHBondContact O-CB 3.31Å; N329-S333 PolarHBondContact O-N 3.04Å; N329-S333 PolarHBondContact O-OG 3.21Å; N329-S333 PolarHBondContact OD1-OG 3.38Å
330	G	83.1	Confident	83.8	Confident	0 Å²	0	36.2 Å²	36.2	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-58.7	-42.4	176.2	0	0	0	0	0	112.7	L215 L326 Q327 A334	L215-G330 CarbonylContact C-O 3.56Å; L326-G330 PolarHBondContact O-N 2.68Å; Q327-G330 PolarHBondContact O-N 3.45Å; G330-A334 PolarHBondContact O-N 3.42Å
331	F	87.1	Confident	84.2	Confident	128 Å²	128	37.6 Å²	37.6	56%	0.561	19%	0.191	S	C	*	.	H	α-helix	trans	-70.2	-49	178.4	-174.1	-96.5	0	0	0	112.9	Q327 S328 N329 S333 A334 L335	Q327-F331 PolarHBondContact O-N 3.26Å; Q327-F331 VanDerWaalsContact O-N 3.11Å; S328-F331 PolarHBondContact O-N 3.01Å; N329-F331 VanDerWaalsContact C-N 3.32Å; N329-F331 PolarHBondContact O-N 3.31Å; F331-S333 VanDerWaalsContact C-N 3.32Å; F331-S333 PolarHBondContact O-N 2.8Å; F331-A334 WeakPolarHBondContact O-CB 3.24Å; F331-A334 PolarHBondContact O-N 3.05Å; F331-L335 PolarHBondContact O-N 2.99Å
332	L	87.9	Confident	84.6	Confident	36 Å²	36	40.5 Å²	40.5	19%	0.188	21%	0.21	C	C	.	.	H	α-helix	trans	-67.9	-31.9	-178.9	-67.2	175	0	0	0	112.2	F324 S328 N329 A334 L335 P336 V395	F324-L332 HydrophobicContact CD1-CD1 3.93Å; F324-L332 HydrophobicContact CD2-CD1 4.13Å; F324-L332 HydrophobicContact CE1-CD1 3.66Å; F324-L332 HydrophobicContact CE2-CD1 3.84Å; F324-L332 HydrophobicContact CG-CD1 4.16Å; F324-L332 HydrophobicContact CZ-CD1 3.58Å; S328-L332 VanDerWaalsContact O-CB 3.26Å; S328-L332 WeakPolarHBondContact O-CB 3.43Å; S328-L332 WeakPolarHBondContact O-CG 3.45Å; S328-L332 PolarHBondContact O-N 3.45Å; N329-L332 PolarHBondContact O-N 2.82Å; L332-A334 VanDerWaalsContact C-N 3.29Å; L332-A334 PolarHBondContact O-N 3.38Å; L332-L335 PolarHBondContact O-N 3.47Å; L332-P336 VanDerWaalsContact O-CD 3.3Å; L332-P336 WeakPolarHBondContact O-CD 3.42Å; L332-V395 HydrophobicContact CD2-CG1 4.28Å
333	S	87	Confident	85.2	Confident	1 Å²	1	42.3 Å²	42.3	1%	0.007	22%	0.22	C	C	.	.	H	α-helix	trans	-70.3	-23.5	174.3	-68.1	0	0	0	0	113.1	N329 F331 Y337	N329-S333 WeakPolarHBondContact O-CB 3.31Å; N329-S333 PolarHBondContact O-N 3.04Å; N329-S333 PolarHBondContact O-OG 3.21Å; N329-S333 PolarHBondContact OD1-OG 3.38Å; F331-S333 VanDerWaalsContact C-N 3.32Å; F331-S333 PolarHBondContact O-N 2.8Å; S333-Y337 VanDerWaalsContact O-CD2 3.29Å; S333-Y337 WeakPolarHBondContact O-CD2 3.34Å; S333-Y337 VanDerWaalsContact O-CE2 3.25Å; S333-Y337 WeakPolarHBondContact O-CE2 3.33Å
334	A	87.2	Confident	85.7	Confident	5 Å²	5	40.4 Å²	40.4	4%	0.041	22%	0.215	C	C	.	.	H	α-helix	trans	-79.5	-27.5	176.7	0	0	0	0	0	113.1	L215 P216 G330 F331 L332 Y337 F338	L215-A334 HydrophobicContact CB-CB 4.07Å; L215-A334 HydrophobicContact CD1-CB 4.33Å; P216-A334 HydrophobicContact CG-CB 3.67Å; G330-A334 PolarHBondContact O-N 3.42Å; F331-A334 WeakPolarHBondContact O-CB 3.24Å; F331-A334 PolarHBondContact O-N 3.05Å; L332-A334 VanDerWaalsContact C-N 3.29Å; L332-A334 PolarHBondContact O-N 3.38Å; A334-Y337 PolarHBondContact O-N 3Å; A334-F338 PolarHBondContact O-N 3.48Å
335	L	89.9	Confident	86.1	Confident	58 Å²	58	43.9 Å²	43.9	30%	0.304	24%	0.235	S	C	.	.	H	α-helix	trans	-59.1	-42.6	-171.9	-167.7	136.9	0	0	0	114.2	F331 L332 Y337 F338 C339 T399	F331-L335 PolarHBondContact O-N 2.99Å; L332-L335 PolarHBondContact O-N 3.47Å; L335-Y337 VanDerWaalsContact C-N 3.32Å; L335-Y337 PolarHBondContact O-N 2.97Å; L335-F338 PolarHBondContact O-N 2.89Å; L335-C339 PolarHBondContact O-N 2.96Å; L335-C339 PolarHBondContact O-SG 2.86Å; L335-T399 HydrophobicContact CD2-CG2 3.35Å; L335-T399 WeakPolarHBondContact CD2-OG1 3.38Å
336	P	88.1	Confident	86.7	Confident	1 Å²	1	46.7 Å²	46.7	1%	0.006	25%	0.25	C	C	.	.	H	α-helix	trans	-59	-38.7	176.1	-23.7	33.3	0	0	0	113.9	L314 L332 S340 T402	L314-P336 HydrophobicContact CD2-CG 4.16Å; L332-P336 VanDerWaalsContact O-CD 3.3Å; L332-P336 WeakPolarHBondContact O-CD 3.42Å; P336-S340 PolarHBondContact O-N 3.31Å; P336-T402 HydrophobicContact CB-CG2 3.97Å; P336-T402 WeakPolarHBondContact CB-OG1 3.35Å
337	Y	86.2	Confident	87.5	Confident	12 Å²	12	46.8 Å²	46.8	5%	0.047	25%	0.251	C	S	.	.	H	α-helix	trans	-75.8	-36.2	179.7	-56.3	-70.5	0	0	0	112.1	L215 F307 L310 L311 S333 A334 L335 C339 S340 T402	L215-Y337 HydrophobicContact CD1-CD2 3.93Å; L215-Y337 HydrophobicContact CD1-CE2 4.08Å; F307-Y337 HydrophobicContact CD2-CE1 4.14Å; F307-Y337 AromaticContact CE2-CD1 3.79Å; F307-Y337 HydrophobicContact CE2-CD1 3.79Å; F307-Y337 AromaticContact CE2-CE1 3.66Å; F307-Y337 HydrophobicContact CE2-CE1 3.66Å; F307-Y337 HydrophobicContact CZ-CD1 4.4Å; F307-Y337 HydrophobicContact CZ-CE1 4.26Å; L310-Y337 PolarHBondContact O-OH 3.34Å; L311-Y337 WeakPolarHBondContact CA-OH 3.29Å; L311-Y337 HydrophobicContact CD1-CE1 3.9Å; L311-Y337 HydrophobicContact CD1-CE2 4.06Å; L311-Y337 PolarHBondContact N-OH 3.29Å; S333-Y337 VanDerWaalsContact O-CD2 3.29Å; S333-Y337 WeakPolarHBondContact O-CD2 3.34Å; S333-Y337 VanDerWaalsContact O-CE2 3.25Å; S333-Y337 WeakPolarHBondContact O-CE2 3.33Å; A334-Y337 PolarHBondContact O-N 3Å; L335-Y337 VanDerWaalsContact C-N 3.32Å; L335-Y337 PolarHBondContact O-N 2.97Å; Y337-C339 VanDerWaalsContact C-N 3.35Å; Y337-S340 PolarHBondContact O-N 2.91Å; Y337-S340 PolarHBondContact O-OG 3.48Å; Y337-T402 HydrophobicContact CD1-CG2 4.12Å; Y337-T402 HydrophobicContact CE1-CG2 4.04Å
338	F	87.3	Confident	87.9	Confident	132 Å²	132	43.8 Å²	43.8	58%	0.579	24%	0.242	S	C	*	.	H	α-helix	trans	-63	-44.7	174.2	-176.8	-100.1	0	0	0	111	A334 L335 S340 P342	A334-F338 PolarHBondContact O-N 3.48Å; L335-F338 PolarHBondContact O-N 2.89Å; F338-S340 VanDerWaalsContact C-N 3.35Å; F338-S340 PolarHBondContact O-N 3.45Å; F338-P342 WeakPolarHBondContact O-CD 3.43Å
339	C	89.6	Confident	88.3	Confident	39 Å²	39	46.5 Å²	46.5	26%	0.264	26%	0.257	S	S	.	.	H	α-helix	trans	-71.9	-23.9	178.4	-67.8	0	0	0	0	113.5	L335 Y337 P342 V343 T399 S403	L335-C339 PolarHBondContact O-N 2.96Å; L335-C339 PolarHBondContact O-SG 2.86Å; Y337-C339 VanDerWaalsContact C-N 3.35Å; C339-P342 VanDerWaalsContact O-CD 3.3Å; C339-P342 WeakPolarHBondContact O-CD 3.27Å; C339-P342 VanDerWaalsContact O-CG 3.32Å; C339-P342 WeakPolarHBondContact O-CG 3.3Å; C339-V343 WeakPolarHBondContact O-CG2 3.31Å; C339-T399 HydrophobicContact CB-CG2 4.11Å; C339-S403 WeakPolarHBondContact CB-OG 3.38Å
340	S	89.3	Confident	88.7	Confident	18 Å²	18	48.4 Å²	48.4	13%	0.126	27%	0.273	C	S	.	.	H	α-helix	trans	-71	-30.8	176.8	69.3	0	0	0	0	113.8	P336 Y337 F338 V343 S344	P336-S340 PolarHBondContact O-N 3.31Å; Y337-S340 PolarHBondContact O-N 2.91Å; Y337-S340 PolarHBondContact O-OG 3.48Å; F338-S340 VanDerWaalsContact C-N 3.35Å; F338-S340 PolarHBondContact O-N 3.45Å; S340-V343 PolarHBondContact O-N 3.36Å; S340-S344 WeakPolarHBondContact O-CB 3.31Å; S340-S344 PolarHBondContact O-N 2.9Å; S340-S344 PolarHBondContact O-OG 3.22Å
341	V	87.1	Confident	89	Confident	51 Å²	51	48.4 Å²	48.4	31%	0.309	27%	0.273	S	S	.	.	H	α-helix	trans	-58.2	-57.1	178.3	175.3	0	0	0	0	112.5	V343 S344 L345	V341-V343 VanDerWaalsContact C-N 3.31Å; V341-V343 PolarHBondContact O-N 3.4Å; V341-S344 PolarHBondContact O-N 2.85Å; V341-S344 PolarHBondContact O-OG 3.31Å; V341-L345 HydrophobicContact CG1-CD1 4.27Å; V341-L345 WeakPolarHBondContact O-CG 3.27Å; V341-L345 PolarHBondContact O-N 3.15Å; V341-L345 VanDerWaalsContact O-N 3.1Å
342	P	90.1	Very high	89.1	Confident	62 Å²	62	46.2 Å²	46.2	40%	0.403	27%	0.267	S	S	.	.	H	α-helix	trans	-62.6	-36.8	179.8	24.5	-33.8	0	0	0	112.2	F338 C339 S344 L345 L346	F338-P342 WeakPolarHBondContact O-CD 3.43Å; C339-P342 VanDerWaalsContact O-CD 3.3Å; C339-P342 WeakPolarHBondContact O-CD 3.27Å; C339-P342 VanDerWaalsContact O-CG 3.32Å; C339-P342 WeakPolarHBondContact O-CG 3.3Å; P342-S344 VanDerWaalsContact C-N 3.35Å; P342-S344 PolarHBondContact O-N 3.07Å; P342-L345 PolarHBondContact O-N 3.42Å; P342-L346 WeakPolarHBondContact O-CB 3.5Å; P342-L346 VanDerWaalsContact O-CG 3.24Å; P342-L346 WeakPolarHBondContact O-CG 3.48Å; P342-L346 PolarHBondContact O-N 3.25Å
343	V	91.5	Very high	89.2	Confident	39 Å²	39	50.7 Å²	50.7	24%	0.236	28%	0.281	C	S	.	.	H	α-helix	trans	-62.1	-43.5	175.7	177.4	0	0	0	0	111.1	C339 S340 V341 L345 L346 S347 S403	C339-V343 WeakPolarHBondContact O-CG2 3.31Å; S340-V343 PolarHBondContact O-N 3.36Å; V341-V343 VanDerWaalsContact C-N 3.31Å; V341-V343 PolarHBondContact O-N 3.4Å; V343-L345 VanDerWaalsContact C-N 3.31Å; V343-L345 PolarHBondContact O-N 3.11Å; V343-L346 PolarHBondContact O-N 3.34Å; V343-S347 WeakPolarHBondContact O-CB 3.23Å; V343-S347 PolarHBondContact O-N 3.3Å; V343-S347 PolarHBondContact O-OG 3.23Å; V343-S347 VanDerWaalsContact O-OG 3.1Å; V343-S403 VanDerWaalsContact CB-O 3.31Å; V343-S403 WeakPolarHBondContact CB-O 3.42Å; V343-S403 WeakPolarHBondContact CG1-O 3.48Å
344	S	89.1	Confident	89.4	Confident	32 Å²	32	51.9 Å²	51.9	22%	0.224	29%	0.288	C	S	.	.	H	α-helix	trans	-63.4	-34.5	178.1	75.9	0	0	0	0	113.3	S340 V341 P342 S347 G348 G406 S409	S340-S344 WeakPolarHBondContact O-CB 3.31Å; S340-S344 PolarHBondContact O-N 2.9Å; S340-S344 PolarHBondContact O-OG 3.22Å; V341-S344 PolarHBondContact O-N 2.85Å; V341-S344 PolarHBondContact O-OG 3.31Å; P342-S344 VanDerWaalsContact C-N 3.35Å; P342-S344 PolarHBondContact O-N 3.07Å; S344-S347 VanDerWaalsContact C-OG 3.31Å; S344-S347 WeakPolarHBondContact CA-OG 3.44Å; S344-S347 PolarHBondContact O-OG 3.2Å; S344-G348 PolarHBondContact O-N 2.92Å; S344-G406 WeakPolarHBondContact CA-O 3.24Å; S344-G406 WeakPolarHBondContact CB-O 3.23Å; S344-S409 PolarHBondContact O-OG 3.31Å
345	L	88.8	Confident	89.5	Confident	114 Å²	114	53.2 Å²	53.2	60%	0.597	29%	0.294	S	S	*	.	H	α-helix	trans	-72.8	-46.7	175.9	-68.2	174	0	0	0	111	V341 P342 V343 S347 G348 V349	V341-L345 HydrophobicContact CG1-CD1 4.27Å; V341-L345 WeakPolarHBondContact O-CG 3.27Å; V341-L345 PolarHBondContact O-N 3.15Å; V341-L345 VanDerWaalsContact O-N 3.1Å; P342-L345 PolarHBondContact O-N 3.42Å; V343-L345 VanDerWaalsContact C-N 3.31Å; V343-L345 PolarHBondContact O-N 3.11Å; L345-S347 VanDerWaalsContact C-N 3.3Å; L345-S347 PolarHBondContact O-N 2.94Å; L345-G348 PolarHBondContact O-N 3.31Å; L345-G348 VanDerWaalsContact O-N 3.15Å; L345-V349 PolarHBondContact O-N 3.25Å
346	L	91.4	Very high	89.4	Confident	119 Å²	119	57.7 Å²	57.7	62%	0.623	32%	0.315	S	S	*	.	H	α-helix	trans	-61.9	-38.8	177.4	-70.8	172.3	0	0	0	111.6	P342 V343 G348 V349 A350	P342-L346 WeakPolarHBondContact O-CB 3.5Å; P342-L346 VanDerWaalsContact O-CG 3.24Å; P342-L346 WeakPolarHBondContact O-CG 3.48Å; P342-L346 PolarHBondContact O-N 3.25Å; V343-L346 PolarHBondContact O-N 3.34Å; L346-G348 VanDerWaalsContact C-N 3.33Å; L346-G348 PolarHBondContact O-N 2.91Å; L346-V349 PolarHBondContact O-N 3.36Å; L346-A350 VanDerWaalsContact O-CB 3.22Å; L346-A350 WeakPolarHBondContact O-CB 3.36Å; L346-A350 PolarHBondContact O-N 3.45Å
347	S	91.5	Very high	89.4	Confident	7 Å²	7	65.7 Å²	65.7	5%	0.049	35%	0.345	C	S	.	.	H	α-helix	trans	-64.4	-37.5	174.8	57.1	0	0	0	0	112.3	V343 S344 L345 A351 S409 A410	V343-S347 WeakPolarHBondContact O-CB 3.23Å; V343-S347 PolarHBondContact O-N 3.3Å; V343-S347 PolarHBondContact O-OG 3.23Å; V343-S347 VanDerWaalsContact O-OG 3.1Å; S344-S347 VanDerWaalsContact C-OG 3.31Å; S344-S347 WeakPolarHBondContact CA-OG 3.44Å; S344-S347 PolarHBondContact O-OG 3.2Å; L345-S347 VanDerWaalsContact C-N 3.3Å; L345-S347 PolarHBondContact O-N 2.94Å; S347-A351 VanDerWaalsContact O-CB 3.27Å; S347-A351 WeakPolarHBondContact O-CB 3.46Å; S347-A351 PolarHBondContact O-N 3.28Å; S347-S409 PolarHBondContact OG-OG 3.16Å; S347-A410 WeakPolarHBondContact O-CB 3.38Å
348	G	87.9	Confident	89.4	Confident	22 Å²	22	72.6 Å²	72.6	23%	0.227	38%	0.378	C	S	.	.	H	α-helix	trans	-62.5	-51.6	174.8	0	0	0	0	0	111.8	S344 L345 L346 A350 A351 D352	S344-G348 PolarHBondContact O-N 2.92Å; L345-G348 PolarHBondContact O-N 3.31Å; L345-G348 VanDerWaalsContact O-N 3.15Å; L346-G348 VanDerWaalsContact C-N 3.33Å; L346-G348 PolarHBondContact O-N 2.91Å; G348-A350 VanDerWaalsContact C-N 3.31Å; G348-A350 PolarHBondContact O-N 3.41Å; G348-A351 PolarHBondContact O-N 2.9Å; G348-D352 PolarHBondContact O-N 3.5Å
349	V	90.5	Very high	89.3	Confident	101 Å²	101	70 Å²	70	61%	0.612	37%	0.372	S	S	*	.	H	α-helix	trans	-60.4	-41.5	177.6	175.9	0	0	0	0	111.6	L345 L346 W353	L345-V349 PolarHBondContact O-N 3.25Å; L346-V349 PolarHBondContact O-N 3.36Å; V349-W353 VanDerWaalsContact O-CB 3.3Å; V349-W353 WeakPolarHBondContact O-CB 3.27Å; V349-W353 PolarHBondContact O-N 3.45Å
350	A	91.6	Very high	89.3	Confident	40 Å²	40	72.3 Å²	72.3	33%	0.331	38%	0.378	S	S	.	.	H	α-helix	trans	-66.4	-39.9	177.4	0	0	0	0	0	112.2	L346 G348 W353 L354 F369	L346-A350 VanDerWaalsContact O-CB 3.22Å; L346-A350 WeakPolarHBondContact O-CB 3.36Å; L346-A350 PolarHBondContact O-N 3.45Å; G348-A350 VanDerWaalsContact C-N 3.31Å; G348-A350 PolarHBondContact O-N 3.41Å; A350-W353 PolarHBondContact O-N 2.82Å; A350-L354 VanDerWaalsContact O-CG 3.31Å; A350-L354 WeakPolarHBondContact O-CG 3.45Å; A350-L354 PolarHBondContact O-N 3.01Å; A350-F369 HydrophobicContact CB-CE1 4.4Å; A350-F369 HydrophobicContact CB-CZ 3.85Å
351	A	90.3	Very high	89.3	Confident	0 Å²	0	74.5 Å²	74.5	0%	0	39%	0.393	C	S	.	.	H	α-helix	trans	-62.8	-48.4	175.1	0	0	0	0	0	111.4	S347 G348 W353 L354 I355 V365 F369 A410	S347-A351 VanDerWaalsContact O-CB 3.27Å; S347-A351 WeakPolarHBondContact O-CB 3.46Å; S347-A351 PolarHBondContact O-N 3.28Å; G348-A351 PolarHBondContact O-N 2.9Å; A351-W353 VanDerWaalsContact C-N 3.31Å; A351-W353 PolarHBondContact O-N 3.01Å; A351-L354 PolarHBondContact O-N 3.33Å; A351-I355 VanDerWaalsContact O-CG1 3.27Å; A351-I355 WeakPolarHBondContact O-CG1 3.36Å; A351-I355 PolarHBondContact O-N 3.32Å; A351-V365 HydrophobicContact CB-CG1 3.79Å; A351-F369 HydrophobicContact CB-CD2 3.89Å; A351-F369 HydrophobicContact CB-CE2 3.52Å; A351-F369 HydrophobicContact CB-CZ 4.04Å; A351-A410 HydrophobicContact CB-CB 3.95Å
352	D	89	Confident	89.3	Confident	81 Å²	81	75.4 Å²	75.4	43%	0.433	40%	0.396	S	S	.	.	H	α-helix	trans	-61.4	-41.6	178.2	-69.3	-15.4	0	0	0	111.2	G348 L354 I355 M356	G348-D352 PolarHBondContact O-N 3.5Å; D352-L354 PolarHBondContact O-N 2.77Å; D352-I355 PolarHBondContact O-N 3.37Å; D352-M356 VanDerWaalsContact O-CB 3.31Å; D352-M356 WeakPolarHBondContact O-CB 3.27Å; D352-M356 VanDerWaalsContact O-CG 3.24Å; D352-M356 WeakPolarHBondContact O-CG 3.22Å; D352-M356 PolarHBondContact O-N 2.67Å
353	W	90	Very high	89.3	Confident	130 Å²	130	73.4 Å²	73.4	49%	0.492	38%	0.382	S	S	.	.	H	α-helix	trans	-61.5	-42.9	175.8	-179.3	90.2	0	0	0	112.7	V349 A350 A351 R357	V349-W353 VanDerWaalsContact O-CB 3.3Å; V349-W353 WeakPolarHBondContact O-CB 3.27Å; V349-W353 PolarHBondContact O-N 3.45Å; A350-W353 PolarHBondContact O-N 2.82Å; A351-W353 VanDerWaalsContact C-N 3.31Å; A351-W353 PolarHBondContact O-N 3.01Å; W353-R357 VanDerWaalsContact NE1-NE 3.1Å; W353-R357 WeakPolarHBondContact O-CB 3.15Å; W353-R357 WeakPolarHBondContact O-CG 3.09Å; W353-R357 PolarHBondContact O-N 3.19Å
354	L	90.4	Very high	89.4	Confident	27 Å²	27	75.1 Å²	75.1	14%	0.141	39%	0.39	C	S	.	.	H	α-helix	trans	-64.8	-38.8	177.1	-73.9	170.1	0	0	0	112.2	A350 A351 D352 Q358 V359 F360 V365 F369	A350-L354 VanDerWaalsContact O-CG 3.31Å; A350-L354 WeakPolarHBondContact O-CG 3.45Å; A350-L354 PolarHBondContact O-N 3.01Å; A351-L354 PolarHBondContact O-N 3.33Å; D352-L354 PolarHBondContact O-N 2.77Å; L354-Q358 PolarHBondContact O-N 2.81Å; L354-V359 HydrophobicContact CD2-CB 4.23Å; L354-V359 HydrophobicContact CD2-CG1 4.32Å; L354-V359 PolarHBondContact O-N 2.75Å; L354-V359 VanDerWaalsContact O-N 3.15Å; L354-F360 HydrophobicContact CD2-CD2 4.05Å; L354-F360 HydrophobicContact CD2-CE2 4.24Å; L354-V365 HydrophobicContact CB-CG2 4.01Å; L354-F369 HydrophobicContact CD1-CE2 4.02Å; L354-F369 HydrophobicContact CD1-CZ 4.39Å
355	I	88.9	Confident	89.5	Confident	32 Å²	32	73.6 Å²	73.6	16%	0.164	38%	0.38	C	S	.	.	H	α-helix	trans	-71.2	-47.8	177.9	-65.4	168	0	0	0	110.5	A351 D352 R357 Q358 I362 V365	A351-I355 VanDerWaalsContact O-CG1 3.27Å; A351-I355 WeakPolarHBondContact O-CG1 3.36Å; A351-I355 PolarHBondContact O-N 3.32Å; D352-I355 PolarHBondContact O-N 3.37Å; I355-R357 VanDerWaalsContact C-N 3.32Å; I355-R357 PolarHBondContact O-N 2.91Å; I355-Q358 PolarHBondContact O-N 2.91Å; I355-Q358 PolarHBondContact O-NE2 3.38Å; I355-I362 HydrophobicContact CG2-CG1 4.24Å; I355-V365 HydrophobicContact CD1-CB 4.43Å; I355-V365 HydrophobicContact CD1-CG1 4.13Å; I355-V365 HydrophobicContact CG1-CB 4.16Å; I355-V365 HydrophobicContact CG1-CG1 4.11Å; I355-V365 HydrophobicContact CG1-CG2 3.88Å
356	M	88.8	Confident	89.7	Confident	153 Å²	153	68.9 Å²	68.9	75%	0.754	35%	0.354	S	S	*	.	H	α-helix	trans	-63.3	-37.2	-178.9	-74.9	-177.6	-174.1	0	0	112.5	D352 Q358	D352-M356 VanDerWaalsContact O-CB 3.31Å; D352-M356 WeakPolarHBondContact O-CB 3.27Å; D352-M356 VanDerWaalsContact O-CG 3.24Å; D352-M356 WeakPolarHBondContact O-CG 3.22Å; D352-M356 PolarHBondContact O-N 2.67Å; M356-Q358 PolarHBondContact O-N 3.26Å
357	R	88.9	Confident	89.8	Confident	168 Å²	168	65 Å²	65	63%	0.634	33%	0.332	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.8	1	175.4	-69.6	-159.8	177.3	-146.9	0.2	114	W353 I355 V359	W353-R357 VanDerWaalsContact NE1-NE 3.1Å; W353-R357 WeakPolarHBondContact O-CB 3.15Å; W353-R357 WeakPolarHBondContact O-CG 3.09Å; W353-R357 PolarHBondContact O-N 3.19Å; I355-R357 VanDerWaalsContact C-N 3.32Å; I355-R357 PolarHBondContact O-N 2.91Å; R357-V359 HydrophobicContact CB-CG2 3.76Å; R357-V359 PolarHBondContact O-N 3.47Å; R357-V359 VanDerWaalsContact O-N 3.11Å
358	Q	84.8	Confident	89.9	Confident	158 Å²	158	68.1 Å²	68.1	74%	0.738	35%	0.347	S	S	*	.	T	Hydrogen-bonded Turn	trans	53.4	31.3	-179.5	-61.5	-70.7	-63.7	0	0	112.8	L354 I355 M356	L354-Q358 PolarHBondContact O-N 2.81Å; I355-Q358 PolarHBondContact O-N 2.91Å; I355-Q358 PolarHBondContact O-NE2 3.38Å; M356-Q358 PolarHBondContact O-N 3.26Å
359	V	86.7	Confident	90.2	Very high	76 Å²	76	68.1 Å²	68.1	46%	0.461	34%	0.341	S	S	.	.	S	Bend	trans	-71.5	-38	178.9	-178.9	0	0	0	0	110	L354 R357	L354-V359 HydrophobicContact CD2-CB 4.23Å; L354-V359 HydrophobicContact CD2-CG1 4.32Å; L354-V359 PolarHBondContact O-N 2.75Å; L354-V359 VanDerWaalsContact O-N 3.15Å; R357-V359 HydrophobicContact CB-CG2 3.76Å; R357-V359 PolarHBondContact O-N 3.47Å; R357-V359 VanDerWaalsContact O-N 3.11Å
360	F	88.3	Confident	90.4	Very high	89 Å²	89	63.3 Å²	63.3	39%	0.39	31%	0.312	S	S	.	.	S	Bend	trans	-136.3	155.1	178.3	-66.3	-64.1	0	0	0	110.7	L354 N364 V365 I368	L354-F360 HydrophobicContact CD2-CD2 4.05Å; L354-F360 HydrophobicContact CD2-CE2 4.24Å; F360-N364 HydrophobicContact CB-CB 4.19Å; F360-V365 HydrophobicContact CB-CG2 3.65Å; F360-I368 HydrophobicContact CD2-CD1 4.29Å; F360-I368 HydrophobicContact CE2-CD1 4.28Å
361	S	89.9	Confident	90.6	Very high	63 Å²	63	66 Å²	66	44%	0.441	32%	0.316	S	S	.	.			trans	-66.8	154.7	168.9	66.2	0	0	0	0	111	T363 N364 V365	S361-T363 VanDerWaalsContact C-N 3.27Å; S361-T363 PolarHBondContact O-N 3.31Å; S361-N364 PolarHBondContact O-N 3.22Å; S361-N364 VanDerWaalsContact OG-CG 3.29Å; S361-N364 PolarHBondContact OG-N 2.97Å; S361-N364 PolarHBondContact OG-ND2 3Å; S361-V365 WeakPolarHBondContact O-CG2 3.43Å; S361-V365 PolarHBondContact O-N 3.34Å
362	I	87.4	Confident	90.8	Very high	70 Å²	70	67.9 Å²	67.9	36%	0.359	33%	0.328	S	S	.	.	H	α-helix	trans	-51.3	-48.6	177.9	-62.1	172.8	0	0	0	110.4	I355 N364 V365 R366 D418	I355-I362 HydrophobicContact CG2-CG1 4.24Å; I362-N364 VanDerWaalsContact C-N 3.32Å; I362-N364 PolarHBondContact O-N 3.44Å; I362-V365 PolarHBondContact O-N 3.39Å; I362-R366 HydrophobicContact CG2-CG 4.27Å; I362-R366 WeakPolarHBondContact O-CG 3.42Å; I362-R366 PolarHBondContact O-N 3.18Å; I362-D418 HydrophobicContact CG2-CB 4.48Å
363	T	89.8	Confident	91	Very high	20 Å²	20	64.1 Å²	64.1	12%	0.123	31%	0.308	C	S	.	.	H	α-helix	trans	-55	-44.5	177	-54.8	0	0	0	0	112.7	S361 R366 K367 N481 G482	S361-T363 VanDerWaalsContact C-N 3.27Å; S361-T363 PolarHBondContact O-N 3.31Å; T363-R366 PolarHBondContact O-N 2.98Å; T363-K367 HydrophobicContact CG2-CD 4.29Å; T363-K367 WeakPolarHBondContact O-CB 3.17Å; T363-K367 VanDerWaalsContact O-CG 3.31Å; T363-K367 WeakPolarHBondContact O-CG 3.5Å; T363-K367 PolarHBondContact O-N 3.15Å; T363-N481 PolarHBondContact OG1-OD1 3.27Å; T363-G482 PolarHBondContact OG1-N 3.12Å; T363-G482 VanDerWaalsContact OG1-N 3.1Å
364	N	92.3	Very high	91.3	Very high	75 Å²	75	57.9 Å²	57.9	40%	0.401	29%	0.285	S	S	.	.	H	α-helix	trans	-69.5	-39.8	-179.1	-73.1	-5.3	0	0	0	111.6	F360 S361 I362 K367 I368	F360-N364 HydrophobicContact CB-CB 4.19Å; S361-N364 PolarHBondContact O-N 3.22Å; S361-N364 VanDerWaalsContact OG-CG 3.29Å; S361-N364 PolarHBondContact OG-N 2.97Å; S361-N364 PolarHBondContact OG-ND2 3Å; I362-N364 VanDerWaalsContact C-N 3.32Å; I362-N364 PolarHBondContact O-N 3.44Å; N364-K367 PolarHBondContact O-N 3.13Å; N364-I368 VanDerWaalsContact O-CG1 3.27Å; N364-I368 WeakPolarHBondContact O-CG1 3.49Å; N364-I368 PolarHBondContact O-N 3.35Å
365	V	91.9	Very high	91.5	Very high	0 Å²	0	57.7 Å²	57.7	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-59.7	-50.9	173.9	176.4	0	0	0	0	110.1	A351 L354 I355 F360 S361 I362 K367 I368 F369	A351-V365 HydrophobicContact CB-CG1 3.79Å; L354-V365 HydrophobicContact CB-CG2 4.01Å; I355-V365 HydrophobicContact CD1-CB 4.43Å; I355-V365 HydrophobicContact CD1-CG1 4.13Å; I355-V365 HydrophobicContact CG1-CB 4.16Å; I355-V365 HydrophobicContact CG1-CG1 4.11Å; I355-V365 HydrophobicContact CG1-CG2 3.88Å; F360-V365 HydrophobicContact CB-CG2 3.65Å; S361-V365 WeakPolarHBondContact O-CG2 3.43Å; S361-V365 PolarHBondContact O-N 3.34Å; I362-V365 PolarHBondContact O-N 3.39Å; V365-K367 VanDerWaalsContact C-N 3.29Å; V365-K367 PolarHBondContact O-N 3.12Å; V365-I368 PolarHBondContact O-N 2.98Å; V365-F369 HydrophobicContact CG1-CD2 3.73Å; V365-F369 HydrophobicContact CG1-CE2 3.76Å; V365-F369 VanDerWaalsContact O-CD2 3.3Å; V365-F369 WeakPolarHBondContact O-CD2 3.39Å; V365-F369 PolarHBondContact O-N 3.33Å; V365-F369 VanDerWaalsContact O-N 3.07Å
366	R	92.6	Very high	91.9	Very high	15 Å²	15	59 Å²	59	6%	0.057	29%	0.292	C	S	.	.	H	α-helix	trans	-59.8	-38.7	178.1	-61.5	-50.8	-175	-156.2	-7.5	112.3	I362 T363 T370 A410 D418	I362-R366 HydrophobicContact CG2-CG 4.27Å; I362-R366 WeakPolarHBondContact O-CG 3.42Å; I362-R366 PolarHBondContact O-N 3.18Å; T363-R366 PolarHBondContact O-N 2.98Å; R366-T370 VanDerWaalsContact O-CB 3.24Å; R366-T370 WeakPolarHBondContact O-CB 3.22Å; R366-T370 PolarHBondContact O-N 2.97Å; R366-T370 PolarHBondContact O-OG1 2.93Å; R366-A410 WeakPolarHBondContact CD-O 3.28Å; R366-A410 PolarHBondContact NH1-O 3.26Å; R366-D418 IonicContact CZ-OD2 2.97Å; R366-D418 VanDerWaalsContact CZ-OD2 3.29Å; R366-D418 IonicContact NE-OD2 3.23Å; R366-D418 PolarHBondContact NE-OD2 3.17Å; R366-D418 IonicContact NH2-OD1 2.86Å; R366-D418 PolarHBondContact NH2-OD1 3.47Å; R366-D418 IonicContact NH2-OD2 2.76Å; R366-D418 PolarHBondContact NH2-OD2 3.06Å
367	K	94.2	Very high	92.1	Very high	39 Å²	39	52 Å²	52	17%	0.17	26%	0.257	C	S	.	.	H	α-helix	trans	-63.8	-46.3	175.5	-80.1	-175.8	-177.9	-167.6	0	112.3	T363 N364 V365 T370 F371 Y476 M477 G480	T363-K367 HydrophobicContact CG2-CD 4.29Å; T363-K367 WeakPolarHBondContact O-CB 3.17Å; T363-K367 VanDerWaalsContact O-CG 3.31Å; T363-K367 WeakPolarHBondContact O-CG 3.5Å; T363-K367 PolarHBondContact O-N 3.15Å; N364-K367 PolarHBondContact O-N 3.13Å; V365-K367 VanDerWaalsContact C-N 3.29Å; V365-K367 PolarHBondContact O-N 3.12Å; K367-T370 PolarHBondContact O-N 3.11Å; K367-F371 VanDerWaalsContact O-CB 3.23Å; K367-F371 WeakPolarHBondContact O-CB 3.4Å; K367-F371 PolarHBondContact O-N 2.89Å; K367-Y476 HydrophobicContact CG-CD1 4.21Å; K367-Y476 HydrophobicContact CG-CE1 4.12Å; K367-M477 HydrophobicContact CB-CE 4.45Å; K367-M477 HydrophobicContact CB-SD 3.74Å; K367-M477 HydrophobicContact CD-SD 4.27Å; K367-M477 WeakPolarHBondContact CE-O 3.42Å; K367-M477 HydrophobicContact CG-SD 4.08Å; K367-M477 PolarHBondContact NZ-O 2.68Å; K367-G480 WeakPolarHBondContact CE-O 3.25Å; K367-G480 PolarHBondContact NZ-O 3.31Å
368	I	94.6	Very high	92.5	Very high	72 Å²	72	44 Å²	44	37%	0.369	23%	0.227	S	C	.	.	H	α-helix	trans	-59.5	-51.8	178.6	-69.8	163.9	0	0	0	110.6	F360 N364 V365 T370 F371 T372	F360-I368 HydrophobicContact CD2-CD1 4.29Å; F360-I368 HydrophobicContact CE2-CD1 4.28Å; N364-I368 VanDerWaalsContact O-CG1 3.27Å; N364-I368 WeakPolarHBondContact O-CG1 3.49Å; N364-I368 PolarHBondContact O-N 3.35Å; V365-I368 PolarHBondContact O-N 2.98Å; I368-T370 PolarHBondContact O-N 3.48Å; I368-F371 PolarHBondContact O-N 3.43Å; I368-T372 WeakPolarHBondContact O-CG2 3.36Å; I368-T372 PolarHBondContact O-N 3.43Å; I368-T372 PolarHBondContact O-OG1 3.1Å
369	F	93.9	Very high	93	Very high	22 Å²	22	41 Å²	41	10%	0.096	22%	0.215	C	C	.	.	H	α-helix	trans	-67.8	-33.4	-178	-78.7	-75.7	0	0	0	113.4	A350 A351 L354 V365 T372 G373 A410	A350-F369 HydrophobicContact CB-CE1 4.4Å; A350-F369 HydrophobicContact CB-CZ 3.85Å; A351-F369 HydrophobicContact CB-CD2 3.89Å; A351-F369 HydrophobicContact CB-CE2 3.52Å; A351-F369 HydrophobicContact CB-CZ 4.04Å; L354-F369 HydrophobicContact CD1-CE2 4.02Å; L354-F369 HydrophobicContact CD1-CZ 4.39Å; V365-F369 HydrophobicContact CG1-CD2 3.73Å; V365-F369 HydrophobicContact CG1-CE2 3.76Å; V365-F369 VanDerWaalsContact O-CD2 3.3Å; V365-F369 WeakPolarHBondContact O-CD2 3.39Å; V365-F369 PolarHBondContact O-N 3.33Å; V365-F369 VanDerWaalsContact O-N 3.07Å; F369-T372 WeakPolarHBondContact CA-OG1 3.22Å; F369-T372 PolarHBondContact O-OG1 3.3Å; F369-T372 VanDerWaalsContact O-OG1 3.08Å; F369-G373 PolarHBondContact O-N 3.4Å; F369-A410 HydrophobicContact CB-CB 4.38Å; F369-A410 HydrophobicContact CD1-CB 4.2Å; F369-A410 HydrophobicContact CG-CB 4.12Å
370	T	94.7	Very high	93.4	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-70.9	-40.8	174.5	-55.8	0	0	0	0	111.3	T299 R366 K367 I368 G373 L374 G411 V412 Y476	T299-T370 HydrophobicContact CG2-CG2 3.63Å; R366-T370 VanDerWaalsContact O-CB 3.24Å; R366-T370 WeakPolarHBondContact O-CB 3.22Å; R366-T370 PolarHBondContact O-N 2.97Å; R366-T370 PolarHBondContact O-OG1 2.93Å; K367-T370 PolarHBondContact O-N 3.11Å; I368-T370 PolarHBondContact O-N 3.48Å; T370-G373 PolarHBondContact O-N 2.67Å; T370-L374 HydrophobicContact CG2-CD1 3.62Å; T370-L374 WeakPolarHBondContact O-CB 3.49Å; T370-L374 PolarHBondContact O-N 3.21Å; T370-L374 VanDerWaalsContact O-N 3.1Å; T370-G411 VanDerWaalsContact OG1-CA 3.29Å; T370-G411 WeakPolarHBondContact OG1-CA 3.22Å; T370-V412 HydrophobicContact CG2-CB 4.18Å; T370-V412 PolarHBondContact OG1-N 3.19Å; T370-Y476 HydrophobicContact CG2-CD1 3.51Å; T370-Y476 HydrophobicContact CG2-CD2 4.18Å; T370-Y476 HydrophobicContact CG2-CE1 3.92Å; T370-Y476 HydrophobicContact CG2-CG 3.64Å; T370-Y476 WeakPolarHBondContact OG1-CE1 2.83Å
371	F	95.6	Very high	93.7	Very high	96 Å²	96	35.5 Å²	35.5	42%	0.421	19%	0.186	S	C	.	.	H	α-helix	trans	-61.9	-49.8	175.6	179	-90.7	0	0	0	111.2	K367 I368 G373 L374 V375 M477	K367-F371 VanDerWaalsContact O-CB 3.23Å; K367-F371 WeakPolarHBondContact O-CB 3.4Å; K367-F371 PolarHBondContact O-N 2.89Å; I368-F371 PolarHBondContact O-N 3.43Å; F371-G373 VanDerWaalsContact C-N 3.32Å; F371-G373 PolarHBondContact O-N 2.82Å; F371-L374 PolarHBondContact O-N 3.24Å; F371-V375 HydrophobicContact CD2-CG2 3.77Å; F371-V375 HydrophobicContact CE1-CB 4.33Å; F371-V375 HydrophobicContact CE1-CG1 4.47Å; F371-V375 HydrophobicContact CE1-CG2 4.38Å; F371-V375 HydrophobicContact CE2-CB 4.41Å; F371-V375 HydrophobicContact CE2-CG2 3.63Å; F371-V375 HydrophobicContact CG-CG2 4.22Å; F371-V375 HydrophobicContact CZ-CB 4.23Å; F371-V375 HydrophobicContact CZ-CG1 4.17Å; F371-V375 HydrophobicContact CZ-CG2 3.95Å; F371-V375 VanDerWaalsContact O-CB 3.29Å; F371-V375 WeakPolarHBondContact O-CB 3.39Å; F371-V375 WeakPolarHBondContact O-CG2 3.33Å; F371-V375 PolarHBondContact O-N 3.48Å; F371-M477 HydrophobicContact CB-SD 4.15Å; F371-M477 HydrophobicContact CD2-CG 4.17Å; F371-M477 HydrophobicContact CD2-SD 4.4Å
372	T	94.4	Very high	93.9	Very high	39 Å²	39	33.9 Å²	33.9	24%	0.239	17%	0.171	C	C	.	.	H	α-helix	trans	-63.6	-39.9	177.8	55.6	0	0	0	0	111.6	I368 F369 L374 L376 P377	I368-T372 WeakPolarHBondContact O-CG2 3.36Å; I368-T372 PolarHBondContact O-N 3.43Å; I368-T372 PolarHBondContact O-OG1 3.1Å; F369-T372 WeakPolarHBondContact CA-OG1 3.22Å; F369-T372 PolarHBondContact O-OG1 3.3Å; F369-T372 VanDerWaalsContact O-OG1 3.08Å; T372-L374 VanDerWaalsContact C-N 3.28Å; T372-L374 PolarHBondContact O-N 3.18Å; T372-L376 HydrophobicContact CG2-CD1 4.43Å; T372-L376 WeakPolarHBondContact O-CB 3.04Å; T372-L376 WeakPolarHBondContact O-CG 3.3Å; T372-L376 PolarHBondContact O-N 2.9Å; T372-P377 WeakPolarHBondContact O-CD 3.48Å
373	G	93.2	Very high	94.1	Very high	2 Å²	2	31.9 Å²	31.9	2%	0.021	17%	0.165	C	C	.	.	H	α-helix	trans	-73	-8	179.6	0	0	0	0	0	116.1	F369 T370 F371 P377 G405 S408	F369-G373 PolarHBondContact O-N 3.4Å; T370-G373 PolarHBondContact O-N 2.67Å; F371-G373 VanDerWaalsContact C-N 3.32Å; F371-G373 PolarHBondContact O-N 2.82Å; G373-P377 WeakPolarHBondContact O-CG 3.41Å; G373-G405 WeakPolarHBondContact O-CA 3.19Å; G373-S408 VanDerWaalsContact C-OG 3.29Å; G373-S408 WeakPolarHBondContact CA-OG 3.47Å; G373-S408 PolarHBondContact O-OG 3.46Å; G373-S408 VanDerWaalsContact O-OG 3.04Å
374	L	94.9	Very high	94.1	Very high	0 Å²	0	31 Å²	31	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-117.9	-44.1	176.6	-76.8	159.6	0	0	0	112.3	T299 C302 T370 F371 T372 A378 N469 A473	T299-L374 HydrophobicContact CG2-CD1 3.52Å; C302-L374 HydrophobicContact CB-CD2 4.43Å; T370-L374 HydrophobicContact CG2-CD1 3.62Å; T370-L374 WeakPolarHBondContact O-CB 3.49Å; T370-L374 PolarHBondContact O-N 3.21Å; T370-L374 VanDerWaalsContact O-N 3.1Å; F371-L374 PolarHBondContact O-N 3.24Å; T372-L374 VanDerWaalsContact C-N 3.28Å; T372-L374 PolarHBondContact O-N 3.18Å; L374-A378 WeakPolarHBondContact O-CB 3.21Å; L374-A378 PolarHBondContact O-N 2.91Å; L374-N469 HydrophobicContact CB-CB 4.44Å; L374-N469 HydrophobicContact CD2-CB 4.06Å; L374-N469 WeakPolarHBondContact O-CB 3.12Å; L374-A473 HydrophobicContact CB-CB 3.88Å; L374-A473 HydrophobicContact CD1-CB 4.16Å
375	V	96.7	Very high	93.9	Very high	22 Å²	22	27.7 Å²	27.7	13%	0.133	14%	0.143	C	C	.	.	H	α-helix	trans	-75.1	-45.1	-176.1	178.5	0	0	0	0	111.6	F371 A378 L379 A473	F371-V375 HydrophobicContact CD2-CG2 3.77Å; F371-V375 HydrophobicContact CE1-CB 4.33Å; F371-V375 HydrophobicContact CE1-CG1 4.47Å; F371-V375 HydrophobicContact CE1-CG2 4.38Å; F371-V375 HydrophobicContact CE2-CB 4.41Å; F371-V375 HydrophobicContact CE2-CG2 3.63Å; F371-V375 HydrophobicContact CG-CG2 4.22Å; F371-V375 HydrophobicContact CZ-CB 4.23Å; F371-V375 HydrophobicContact CZ-CG1 4.17Å; F371-V375 HydrophobicContact CZ-CG2 3.95Å; F371-V375 VanDerWaalsContact O-CB 3.29Å; F371-V375 WeakPolarHBondContact O-CB 3.39Å; F371-V375 WeakPolarHBondContact O-CG2 3.33Å; F371-V375 PolarHBondContact O-N 3.48Å; V375-A378 WeakPolarHBondContact O-CB 3.43Å; V375-A378 PolarHBondContact O-N 3.35Å; V375-L379 HydrophobicContact CG1-CD1 4.16Å; V375-L379 HydrophobicContact CG1-CG 4.31Å; V375-L379 WeakPolarHBondContact O-CG 3.27Å; V375-L379 PolarHBondContact O-N 3.15Å; V375-A473 HydrophobicContact CG2-CB 3.71Å
376	L	95.3	Very high	93.7	Very high	61 Å²	61	35.4 Å²	35.4	32%	0.319	17%	0.173	S	C	.	.	H	α-helix	trans	-62.6	-45.3	179.1	-58.7	175.8	0	0	0	111.6	T372 A378 L379 F380 L404	T372-L376 HydrophobicContact CG2-CD1 4.43Å; T372-L376 WeakPolarHBondContact O-CB 3.04Å; T372-L376 WeakPolarHBondContact O-CG 3.3Å; T372-L376 PolarHBondContact O-N 2.9Å; L376-A378 VanDerWaalsContact C-N 3.3Å; L376-A378 PolarHBondContact O-N 3.04Å; L376-L379 HydrophobicContact CD2-CD1 4.46Å; L376-L379 PolarHBondContact O-N 3.36Å; L376-F380 WeakPolarHBondContact O-CD2 3.48Å; L376-F380 PolarHBondContact O-N 3.43Å; L376-L404 HydrophobicContact CB-CB 4.28Å; L376-L404 HydrophobicContact CB-CD1 3.92Å; L376-L404 HydrophobicContact CD1-CD1 4.17Å; L376-L404 HydrophobicContact CD1-CD2 4.34Å
377	P	95	Very high	93.3	Very high	5 Å²	5	35.2 Å²	35.2	3%	0.032	17%	0.174	C	C	.	.	H	α-helix	trans	-56.4	-42.4	172.6	-28.6	37.8	0	0	0	113.4	T372 G373 F380 L381 S401 L404	T372-P377 WeakPolarHBondContact O-CD 3.48Å; G373-P377 WeakPolarHBondContact O-CG 3.41Å; P377-F380 PolarHBondContact O-N 3.42Å; P377-L381 WeakPolarHBondContact O-CG 3.1Å; P377-L381 PolarHBondContact O-N 2.99Å; P377-S401 VanDerWaalsContact CA-OG 3.32Å; P377-S401 WeakPolarHBondContact CA-OG 3.2Å; P377-S401 WeakPolarHBondContact CB-O 3.49Å; P377-S401 WeakPolarHBondContact CB-OG 3.36Å; P377-S401 VanDerWaalsContact CG-O 3.29Å; P377-S401 WeakPolarHBondContact CG-O 3.45Å; P377-S401 PolarHBondContact O-OG 2.88Å; P377-L404 HydrophobicContact CG-CB 4.4Å
378	A	95.4	Very high	92.5	Very high	0 Å²	0	34.7 Å²	34.7	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-62	-43.4	177.6	0	0	0	0	0	112.5	L374 V375 L376 F380 L381 I382 A466 N469 I470	L374-A378 WeakPolarHBondContact O-CB 3.21Å; L374-A378 PolarHBondContact O-N 2.91Å; V375-A378 WeakPolarHBondContact O-CB 3.43Å; V375-A378 PolarHBondContact O-N 3.35Å; L376-A378 VanDerWaalsContact C-N 3.3Å; L376-A378 PolarHBondContact O-N 3.04Å; A378-F380 PolarHBondContact O-N 2.97Å; A378-L381 PolarHBondContact O-N 3.07Å; A378-I382 WeakPolarHBondContact O-CG1 3.5Å; A378-I382 PolarHBondContact O-N 3.01Å; A378-A466 HydrophobicContact CB-CB 3.92Å; A378-N469 HydrophobicContact CB-CB 3.99Å; A378-I470 HydrophobicContact CB-CD1 4.05Å; A378-I470 HydrophobicContact CB-CG1 3.76Å
379	L	95.9	Very high	91.7	Very high	94 Å²	94	33.9 Å²	33.9	49%	0.492	18%	0.18	S	C	.	.	H	α-helix	trans	-62.5	-42.1	177	-68.4	175.6	0	0	0	111.8	V375 L376 I382 A383	V375-L379 HydrophobicContact CG1-CD1 4.16Å; V375-L379 HydrophobicContact CG1-CG 4.31Å; V375-L379 WeakPolarHBondContact O-CG 3.27Å; V375-L379 PolarHBondContact O-N 3.15Å; L376-L379 HydrophobicContact CD2-CD1 4.46Å; L376-L379 PolarHBondContact O-N 3.36Å; L379-I382 PolarHBondContact O-N 3.12Å; L379-A383 WeakPolarHBondContact O-CB 3.44Å; L379-A383 PolarHBondContact O-N 2.98Å
380	F	95.6	Very high	91.2	Very high	50 Å²	50	35.4 Å²	35.4	22%	0.219	19%	0.194	C	C	.	.	H	α-helix	trans	-69.2	-35.2	176.3	-77.5	-66.4	0	0	0	112.8	L376 P377 A378 I382 A383 V384 F397 L400 L404	L376-F380 WeakPolarHBondContact O-CD2 3.48Å; L376-F380 PolarHBondContact O-N 3.43Å; P377-F380 PolarHBondContact O-N 3.42Å; A378-F380 PolarHBondContact O-N 2.97Å; F380-I382 VanDerWaalsContact C-N 3.33Å; F380-A383 WeakPolarHBondContact O-CB 3.22Å; F380-A383 PolarHBondContact O-N 3.41Å; F380-V384 WeakPolarHBondContact O-CG2 3.34Å; F380-V384 PolarHBondContact O-N 3.31Å; F380-F397 HydrophobicContact CD1-CB 4.34Å; F380-F397 AromaticContact CD1-CD1 3.71Å; F380-F397 HydrophobicContact CD1-CD1 3.71Å; F380-F397 HydrophobicContact CD1-CE1 4.33Å; F380-F397 HydrophobicContact CD1-CG 4.24Å; F380-F397 AromaticContact CE1-CD1 3.98Å; F380-F397 HydrophobicContact CE1-CD1 3.98Å; F380-F397 HydrophobicContact CE1-CE1 4.27Å; F380-L400 HydrophobicContact CD1-CB 4.14Å; F380-L400 HydrophobicContact CD1-CD1 4.3Å; F380-L400 HydrophobicContact CD2-CB 4.13Å; F380-L400 HydrophobicContact CE1-CB 4.16Å; F380-L400 HydrophobicContact CE1-CD1 3.69Å; F380-L400 HydrophobicContact CE2-CB 4.19Å; F380-L400 HydrophobicContact CG-CB 4.13Å; F380-L400 HydrophobicContact CZ-CB 4.19Å; F380-L400 HydrophobicContact CZ-CD1 3.94Å; F380-L404 HydrophobicContact CD2-CD1 3.82Å; F380-L404 HydrophobicContact CE2-CD1 3.36Å; F380-L404 HydrophobicContact CZ-CD1 4.39Å
381	L	93.8	Very high	90.7	Very high	1 Å²	1	37.9 Å²	37.9	1%	0.005	21%	0.205	C	C	.	.	H	α-helix	trans	-62.8	-40.4	172	-72.7	175.4	0	0	0	111.8	L310 P377 A378 A383 V384 L398 S401 F462 A465	L310-L381 HydrophobicContact CD1-CD2 4.33Å; L310-L381 HydrophobicContact CD2-CD2 4.28Å; P377-L381 WeakPolarHBondContact O-CG 3.1Å; P377-L381 PolarHBondContact O-N 2.99Å; A378-L381 PolarHBondContact O-N 3.07Å; L381-A383 VanDerWaalsContact C-N 3.34Å; L381-V384 WeakPolarHBondContact O-CB 3.3Å; L381-V384 PolarHBondContact O-N 3.16Å; L381-L398 HydrophobicContact CD2-CD2 4.31Å; L381-S401 WeakPolarHBondContact CG-OG 3.41Å; L381-F462 HydrophobicContact CB-CB 4.46Å; L381-F462 HydrophobicContact CD2-CD1 3.88Å; L381-F462 HydrophobicContact CD2-CE1 4.32Å; L381-A465 HydrophobicContact CD1-CB 3.94Å
382	I	93.9	Very high	90.3	Very high	28 Å²	28	39.8 Å²	39.8	14%	0.144	22%	0.218	C	C	.	.	H	α-helix	trans	-65.1	-40.9	173.1	-66.9	167	0	0	0	110.2	A378 L379 F380 V384 C385 Y386 W463 A466	A378-I382 WeakPolarHBondContact O-CG1 3.5Å; A378-I382 PolarHBondContact O-N 3.01Å; L379-I382 PolarHBondContact O-N 3.12Å; F380-I382 VanDerWaalsContact C-N 3.33Å; I382-V384 VanDerWaalsContact C-N 3.27Å; I382-V384 PolarHBondContact O-N 3.09Å; I382-C385 VanDerWaalsContact O-CB 3.25Å; I382-C385 WeakPolarHBondContact O-CB 3.29Å; I382-C385 PolarHBondContact O-N 3.04Å; I382-C385 VanDerWaalsContact O-N 3.08Å; I382-Y386 HydrophobicContact CG2-CD2 4.19Å; I382-Y386 HydrophobicContact CG2-CE2 3.67Å; I382-Y386 WeakPolarHBondContact O-CD2 3.47Å; I382-W463 HydrophobicContact CD1-CE3 4.23Å; I382-W463 HydrophobicContact CD1-CH2 3.98Å; I382-W463 HydrophobicContact CD1-CZ3 3.76Å; I382-W463 HydrophobicContact CG1-CD2 4.4Å; I382-W463 HydrophobicContact CG1-CE3 4.23Å; I382-W463 HydrophobicContact CG1-CH2 4.25Å; I382-W463 HydrophobicContact CG1-CZ2 4.41Å; I382-W463 HydrophobicContact CG1-CZ3 4.15Å; I382-W463 HydrophobicContact CG2-CH2 4.11Å; I382-W463 HydrophobicContact CG2-CZ2 3.86Å; I382-A466 HydrophobicContact CD1-CB 3.87Å; I382-A466 HydrophobicContact CG1-CB 3.67Å
383	A	92.8	Very high	90.1	Very high	28 Å²	28	41.2 Å²	41.2	23%	0.231	22%	0.224	C	C	.	.	H	α-helix	trans	-61.2	-34	177.8	0	0	0	0	0	112.8	L379 F380 L381 C385 Y386 A387 F397	L379-A383 WeakPolarHBondContact O-CB 3.44Å; L379-A383 PolarHBondContact O-N 2.98Å; F380-A383 WeakPolarHBondContact O-CB 3.22Å; F380-A383 PolarHBondContact O-N 3.41Å; L381-A383 VanDerWaalsContact C-N 3.34Å; A383-C385 VanDerWaalsContact C-N 3.28Å; A383-C385 PolarHBondContact O-N 2.83Å; A383-Y386 CarbonylContact O-C 3.46Å; A383-Y386 PolarHBondContact O-N 3.24Å; A383-Y386 VanDerWaalsContact O-N 3.11Å; A383-A387 PolarHBondContact O-N 3.07Å; A383-F397 HydrophobicContact CB-CD2 3.76Å; A383-F397 HydrophobicContact CB-CE2 3.79Å; A383-F397 HydrophobicContact CB-CG 4.26Å; A383-F397 HydrophobicContact CB-CZ 4.32Å
384	V	90.4	Very high	89.9	Confident	2 Å²	2	41.1 Å²	41.1	1%	0.012	22%	0.223	C	C	.	.	H	α-helix	trans	-57.4	-40.6	173.1	169.3	0	0	0	0	111.5	F380 L381 I382 Y386 A387 T394 F397 L398 F462	F380-V384 WeakPolarHBondContact O-CG2 3.34Å; F380-V384 PolarHBondContact O-N 3.31Å; L381-V384 WeakPolarHBondContact O-CB 3.3Å; L381-V384 PolarHBondContact O-N 3.16Å; I382-V384 VanDerWaalsContact C-N 3.27Å; I382-V384 PolarHBondContact O-N 3.09Å; V384-Y386 PolarHBondContact O-N 3.4Å; V384-Y386 VanDerWaalsContact O-N 3.1Å; V384-A387 WeakPolarHBondContact O-CB 3.31Å; V384-A387 PolarHBondContact O-N 3.23Å; V384-A387 VanDerWaalsContact O-N 3.13Å; V384-T394 HydrophobicContact CG1-CG2 4.01Å; V384-F397 HydrophobicContact CG2-CB 3.59Å; V384-L398 HydrophobicContact CG1-CD2 4.5Å; V384-L398 HydrophobicContact CG2-CD2 3.93Å; V384-L398 HydrophobicContact CG2-CG 3.81Å; V384-F462 HydrophobicContact CG1-CD2 3.99Å; V384-F462 HydrophobicContact CG1-CE2 3.65Å; V384-F462 HydrophobicContact CG1-CZ 4.22Å
385	C	87.1	Confident	89.7	Confident	5 Å²	5	42 Å²	42	3%	0.034	23%	0.228	C	C	.	.	H	α-helix	trans	-59.2	-25.9	178.6	-62.8	0	0	0	0	113.6	I382 A383 R459	I382-C385 VanDerWaalsContact O-CB 3.25Å; I382-C385 WeakPolarHBondContact O-CB 3.29Å; I382-C385 PolarHBondContact O-N 3.04Å; I382-C385 VanDerWaalsContact O-N 3.08Å; A383-C385 VanDerWaalsContact C-N 3.28Å; A383-C385 PolarHBondContact O-N 2.83Å; C385-R459 HydrophobicContact CB-CG 3.9Å; C385-R459 PolarHBondContact O-NE 3.28Å
386	Y	87.1	Confident	89.5	Confident	163 Å²	163	44 Å²	44	64%	0.639	24%	0.241	S	C	*	.	H	α-helix	trans	-107.1	-1.7	-178	-58.7	-73.2	0	0	0	113.4	I382 A383 V384 G388	I382-Y386 HydrophobicContact CG2-CD2 4.19Å; I382-Y386 HydrophobicContact CG2-CE2 3.67Å; I382-Y386 WeakPolarHBondContact O-CD2 3.47Å; A383-Y386 CarbonylContact O-C 3.46Å; A383-Y386 PolarHBondContact O-N 3.24Å; A383-Y386 VanDerWaalsContact O-N 3.11Å; V384-Y386 PolarHBondContact O-N 3.4Å; V384-Y386 VanDerWaalsContact O-N 3.1Å; Y386-G388 PolarHBondContact O-N 3.1Å
387	A	83.9	Confident	89.4	Confident	10 Å²	10	43.2 Å²	43.2	8%	0.083	24%	0.235	C	C	.	.	S	Bend	trans	-68.6	-11.6	178.2	0	0	0	0	0	113.1	A383 V384 S390 L393 F397	A383-A387 PolarHBondContact O-N 3.07Å; V384-A387 WeakPolarHBondContact O-CB 3.31Å; V384-A387 PolarHBondContact O-N 3.23Å; V384-A387 VanDerWaalsContact O-N 3.13Å; A387-S390 PolarHBondContact O-N 2.88Å; A387-L393 HydrophobicContact CB-CB 4.41Å; A387-L393 HydrophobicContact CB-CD2 3.84Å; A387-L393 HydrophobicContact CB-CG 4.09Å; A387-F397 HydrophobicContact CB-CD2 4.23Å; A387-F397 HydrophobicContact CB-CE2 4.33Å
388	G	77.4	Confident	89.3	Confident	28 Å²	28	43 Å²	43	29%	0.289	23%	0.234	S	C	.	.	T	Hydrogen-bonded Turn	trans	61.6	-136.4	-177.9	0	0	0	0	0	110.8	Y386 M455	Y386-G388 PolarHBondContact O-N 3.1Å; G388-M455 WeakPolarHBondContact O-CE 3.3Å
389	C	77.6	Confident	89.2	Confident	56 Å²	56	43.7 Å²	43.7	38%	0.378	24%	0.238	S	C	.	.	T	Hydrogen-bonded Turn	trans	-100.1	22.7	-179.6	-69.8	0	0	0	0	114.5	C80 H391	C80-C389 WeakPolarHBondContact CA-SG 3.12Å; C80-C389 HydrophobicContact CB-CB 3.64Å; C80-C389 WeakPolarHBondContact CB-SG 3.44Å; C80-C389 WeakPolarHBondContact SG-CA 3.36Å; C80-C389 WeakPolarHBondContact SG-CB 3.44Å; C80-C389 CovalentContact SG-SG 2.05Å; C80-C389 PolarHBondContact SG-SG 3.1Å; C389-H391 PolarHBondContact O-N 2.84Å; C389-H391 PolarHBondContact O-ND1 3.14Å
390	S	84.1	Confident	89.1	Confident	54 Å²	54	42.4 Å²	42.4	38%	0.378	23%	0.231	S	C	.	.			trans	-79.8	104.4	171.1	-179.6	0	0	0	0	109.9	A387 I392 L393 T394	A387-S390 PolarHBondContact O-N 2.88Å; S390-I392 VanDerWaalsContact C-N 3.32Å; S390-I392 PolarHBondContact O-N 3.45Å; S390-L393 PolarHBondContact O-N 3.49Å; S390-L393 WeakPolarHBondContact OG-CB 3.46Å; S390-L393 PolarHBondContact OG-N 3.31Å; S390-T394 WeakPolarHBondContact O-CB 3.45Å; S390-T394 PolarHBondContact O-N 2.88Å; S390-T394 PolarHBondContact O-OG1 2.88Å
391	H	83.8	Confident	89.1	Confident	52 Å²	52	40.1 Å²	40.1	24%	0.241	22%	0.221	C	C	.	.	H	α-helix	trans	-54.6	-47.5	176.6	-64	74.4	0	0	0	112.1	L322 F324 C389 L393 T394 V395	L322-H391 PolarHBondContact O-CD2 3.44Å; L322-H391 PolarHBondContact O-NE2 3.36Å; F324-H391 AromaticContact CE2-CD2 3.94Å; F324-H391 HydrophobicContact CZ-CB 3.87Å; F324-H391 AromaticContact CZ-CD2 3.68Å; C389-H391 PolarHBondContact O-N 2.84Å; C389-H391 PolarHBondContact O-ND1 3.14Å; H391-L393 PolarHBondContact O-N 2.94Å; H391-T394 PolarHBondContact O-N 3.46Å; H391-V395 VanDerWaalsContact O-CG2 3.29Å; H391-V395 WeakPolarHBondContact O-CG2 3.33Å; H391-V395 PolarHBondContact O-N 3.41Å
392	I	87.6	Confident	89	Confident	136 Å²	136	40.7 Å²	40.7	70%	0.697	23%	0.225	S	C	*	.	H	α-helix	trans	-63.3	-47	-177.4	-61.4	172.5	0	0	0	110.6	S390 T394 T396	S390-I392 VanDerWaalsContact C-N 3.32Å; S390-I392 PolarHBondContact O-N 3.45Å; I392-T394 PolarHBondContact O-N 3.47Å; I392-T396 VanDerWaalsContact O-CB 3.27Å; I392-T396 WeakPolarHBondContact O-CB 3.33Å; I392-T396 PolarHBondContact O-N 3.44Å; I392-T396 PolarHBondContact O-OG1 3.28Å
393	L	89.5	Confident	88.9	Confident	69 Å²	69	39.7 Å²	39.7	36%	0.361	22%	0.221	S	C	.	.	H	α-helix	trans	-64.9	-43	-177.6	-169.5	66.8	0	0	0	111.2	A387 S390 H391 T396 F397	A387-L393 HydrophobicContact CB-CB 4.41Å; A387-L393 HydrophobicContact CB-CD2 3.84Å; A387-L393 HydrophobicContact CB-CG 4.09Å; S390-L393 PolarHBondContact O-N 3.49Å; S390-L393 WeakPolarHBondContact OG-CB 3.46Å; S390-L393 PolarHBondContact OG-N 3.31Å; H391-L393 PolarHBondContact O-N 2.94Å; L393-T396 PolarHBondContact O-N 3.44Å; L393-F397 HydrophobicContact CD1-CD2 4.4Å; L393-F397 HydrophobicContact CD1-CE1 3.88Å; L393-F397 HydrophobicContact CD1-CE2 3.7Å; L393-F397 HydrophobicContact CD1-CZ 3.4Å; L393-F397 HydrophobicContact CD2-CE2 3.84Å; L393-F397 HydrophobicContact CD2-CZ 4.23Å; L393-F397 HydrophobicContact CG-CD2 3.97Å; L393-F397 HydrophobicContact CG-CE1 4.48Å; L393-F397 HydrophobicContact CG-CE2 3.46Å; L393-F397 VanDerWaalsContact CG-CE2 3.46Å; L393-F397 HydrophobicContact CG-CZ 3.76Å; L393-F397 WeakPolarHBondContact O-CG 3.32Å; L393-F397 PolarHBondContact O-N 3.02Å
394	T	89.7	Confident	88.9	Confident	0 Å²	0	40.4 Å²	40.4	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-62.1	-51.5	179.5	-59.8	0	0	0	0	111.7	Y317 L322 V384 S390 H391 I392 T396 F397 L398	Y317-T394 HydrophobicContact CE1-CG2 3.7Å; L322-T394 HydrophobicContact CD1-CG2 3.8Å; L322-T394 HydrophobicContact CD2-CG2 4.43Å; V384-T394 HydrophobicContact CG1-CG2 4.01Å; S390-T394 WeakPolarHBondContact O-CB 3.45Å; S390-T394 PolarHBondContact O-N 2.88Å; S390-T394 PolarHBondContact O-OG1 2.88Å; H391-T394 PolarHBondContact O-N 3.46Å; I392-T394 PolarHBondContact O-N 3.47Å; T394-T396 VanDerWaalsContact C-N 3.28Å; T394-T396 PolarHBondContact O-N 2.91Å; T394-F397 PolarHBondContact O-N 3.38Å; T394-L398 HydrophobicContact CG2-CD1 3.84Å; T394-L398 WeakPolarHBondContact O-CB 3.31Å; T394-L398 VanDerWaalsContact O-CG 3.31Å; T394-L398 WeakPolarHBondContact O-CG 3.47Å; T394-L398 PolarHBondContact O-N 3.43Å
395	V	90.6	Very high	88.9	Confident	17 Å²	17	41.2 Å²	41.2	10%	0.103	23%	0.229	C	C	.	.	H	α-helix	trans	-61.4	-39.9	177.4	174.5	0	0	0	0	110.8	M318 F324 L332 H391 L398 T399	M318-V395 HydrophobicContact CE-CG2 3.95Å; M318-V395 HydrophobicContact SD-CG2 4.08Å; F324-V395 HydrophobicContact CE2-CG2 3.98Å; F324-V395 HydrophobicContact CZ-CG2 4.23Å; L332-V395 HydrophobicContact CD2-CG1 4.28Å; H391-V395 VanDerWaalsContact O-CG2 3.29Å; H391-V395 WeakPolarHBondContact O-CG2 3.33Å; H391-V395 PolarHBondContact O-N 3.41Å; V395-L398 PolarHBondContact O-N 3.34Å; V395-T399 VanDerWaalsContact O-CB 3.3Å; V395-T399 WeakPolarHBondContact O-CB 3.4Å; V395-T399 PolarHBondContact O-N 3.43Å; V395-T399 PolarHBondContact O-OG1 2.93Å
396	T	92.5	Very high	88.9	Confident	65 Å²	65	41.6 Å²	41.6	40%	0.399	23%	0.234	S	C	.	.	H	α-helix	trans	-62.7	-46.5	178.1	-58.4	0	0	0	0	111.4	I392 L393 T394 T399 L400	I392-T396 VanDerWaalsContact O-CB 3.27Å; I392-T396 WeakPolarHBondContact O-CB 3.33Å; I392-T396 PolarHBondContact O-N 3.44Å; I392-T396 PolarHBondContact O-OG1 3.28Å; L393-T396 PolarHBondContact O-N 3.44Å; T394-T396 VanDerWaalsContact C-N 3.28Å; T394-T396 PolarHBondContact O-N 2.91Å; T396-T399 WeakPolarHBondContact O-CB 3.31Å; T396-T399 PolarHBondContact O-N 3.41Å; T396-L400 HydrophobicContact CG2-CD1 4Å; T396-L400 HydrophobicContact CG2-CG 4.45Å; T396-L400 WeakPolarHBondContact O-CB 3.42Å; T396-L400 VanDerWaalsContact O-CG 3.32Å; T396-L400 WeakPolarHBondContact O-CG 3.47Å; T396-L400 PolarHBondContact O-N 3.32Å
397	F	94.3	Very high	89.1	Confident	44 Å²	44	34.4 Å²	34.4	19%	0.193	21%	0.207	C	C	.	.	H	α-helix	trans	-67.6	-39.4	178.3	-68.1	-23.8	0	0	0	113	F380 A383 V384 A387 L393 T394 T399 L400 S401	F380-F397 HydrophobicContact CD1-CB 4.34Å; F380-F397 AromaticContact CD1-CD1 3.71Å; F380-F397 HydrophobicContact CD1-CD1 3.71Å; F380-F397 HydrophobicContact CD1-CE1 4.33Å; F380-F397 HydrophobicContact CD1-CG 4.24Å; F380-F397 AromaticContact CE1-CD1 3.98Å; F380-F397 HydrophobicContact CE1-CD1 3.98Å; F380-F397 HydrophobicContact CE1-CE1 4.27Å; A383-F397 HydrophobicContact CB-CD2 3.76Å; A383-F397 HydrophobicContact CB-CE2 3.79Å; A383-F397 HydrophobicContact CB-CG 4.26Å; A383-F397 HydrophobicContact CB-CZ 4.32Å; V384-F397 HydrophobicContact CG2-CB 3.59Å; A387-F397 HydrophobicContact CB-CD2 4.23Å; A387-F397 HydrophobicContact CB-CE2 4.33Å; L393-F397 HydrophobicContact CD1-CD2 4.4Å; L393-F397 HydrophobicContact CD1-CE1 3.88Å; L393-F397 HydrophobicContact CD1-CE2 3.7Å; L393-F397 HydrophobicContact CD1-CZ 3.4Å; L393-F397 HydrophobicContact CD2-CE2 3.84Å; L393-F397 HydrophobicContact CD2-CZ 4.23Å; L393-F397 HydrophobicContact CG-CD2 3.97Å; L393-F397 HydrophobicContact CG-CE1 4.48Å; L393-F397 HydrophobicContact CG-CE2 3.46Å; L393-F397 VanDerWaalsContact CG-CE2 3.46Å; L393-F397 HydrophobicContact CG-CZ 3.76Å; L393-F397 WeakPolarHBondContact O-CG 3.32Å; L393-F397 PolarHBondContact O-N 3.02Å; T394-F397 PolarHBondContact O-N 3.38Å; F397-T399 VanDerWaalsContact C-N 3.31Å; F397-T399 PolarHBondContact O-N 2.85Å; F397-L400 HydrophobicContact CD1-CD1 4.49Å; F397-L400 PolarHBondContact O-N 3.02Å; F397-S401 VanDerWaalsContact O-CB 3.28Å; F397-S401 WeakPolarHBondContact O-CB 3.22Å; F397-S401 PolarHBondContact O-N 3.15Å
398	L	92.7	Very high	89.4	Confident	1 Å²	1	33.9 Å²	33.9	1%	0.005	20%	0.203	C	C	.	.	H	α-helix	trans	-62.2	-40.7	174.1	-71.7	166	0	0	0	111.8	L310 L314 Y317 M318 L381 V384 T394 V395 S401 T402 F462	L310-L398 HydrophobicContact CD2-CD2 3.97Å; L314-L398 HydrophobicContact CD1-CD1 3.81Å; L314-L398 HydrophobicContact CD1-CD2 4.31Å; L314-L398 HydrophobicContact CD1-CG 4.48Å; Y317-L398 HydrophobicContact CD1-CD1 4.12Å; Y317-L398 HydrophobicContact CE1-CD1 3.87Å; M318-L398 HydrophobicContact CE-CD1 3.67Å; L381-L398 HydrophobicContact CD2-CD2 4.31Å; V384-L398 HydrophobicContact CG1-CD2 4.5Å; V384-L398 HydrophobicContact CG2-CD2 3.93Å; V384-L398 HydrophobicContact CG2-CG 3.81Å; T394-L398 HydrophobicContact CG2-CD1 3.84Å; T394-L398 WeakPolarHBondContact O-CB 3.31Å; T394-L398 VanDerWaalsContact O-CG 3.31Å; T394-L398 WeakPolarHBondContact O-CG 3.47Å; T394-L398 PolarHBondContact O-N 3.43Å; V395-L398 PolarHBondContact O-N 3.34Å; L398-S401 PolarHBondContact O-N 3.34Å; L398-T402 PolarHBondContact O-N 3.1Å; L398-T402 VanDerWaalsContact O-N 3.14Å; L398-T402 PolarHBondContact O-OG1 3.45Å; L398-T402 VanDerWaalsContact O-OG1 3.1Å; L398-F462 HydrophobicContact CD2-CE1 4.23Å; L398-F462 HydrophobicContact CD2-CZ 4.29Å
399	T	93	Very high	89.8	Confident	15 Å²	15	34.3 Å²	34.3	9%	0.092	20%	0.202	C	C	.	.	H	α-helix	trans	-63.4	-51.6	174.9	-59.8	0	0	0	0	111.1	L335 C339 V395 T396 F397 S401 T402 S403	L335-T399 HydrophobicContact CD2-CG2 3.35Å; L335-T399 WeakPolarHBondContact CD2-OG1 3.38Å; C339-T399 HydrophobicContact CB-CG2 4.11Å; V395-T399 VanDerWaalsContact O-CB 3.3Å; V395-T399 WeakPolarHBondContact O-CB 3.4Å; V395-T399 PolarHBondContact O-N 3.43Å; V395-T399 PolarHBondContact O-OG1 2.93Å; T396-T399 WeakPolarHBondContact O-CB 3.31Å; T396-T399 PolarHBondContact O-N 3.41Å; F397-T399 VanDerWaalsContact C-N 3.31Å; F397-T399 PolarHBondContact O-N 2.85Å; T399-S401 VanDerWaalsContact C-N 3.28Å; T399-S401 PolarHBondContact O-N 3.02Å; T399-T402 PolarHBondContact O-N 2.88Å; T399-S403 WeakPolarHBondContact O-CB 3.44Å; T399-S403 PolarHBondContact O-N 2.93Å; T399-S403 PolarHBondContact O-OG 3.34Å
400	L	94.6	Very high	90.2	Very high	66 Å²	66	31.8 Å²	31.8	35%	0.346	19%	0.185	S	C	.	.	H	α-helix	trans	-60.5	-39.8	179.1	-74.9	172.2	0	0	0	111.5	F380 T396 F397 S403 L404	F380-L400 HydrophobicContact CD1-CB 4.14Å; F380-L400 HydrophobicContact CD1-CD1 4.3Å; F380-L400 HydrophobicContact CD2-CB 4.13Å; F380-L400 HydrophobicContact CE1-CB 4.16Å; F380-L400 HydrophobicContact CE1-CD1 3.69Å; F380-L400 HydrophobicContact CE2-CB 4.19Å; F380-L400 HydrophobicContact CG-CB 4.13Å; F380-L400 HydrophobicContact CZ-CB 4.19Å; F380-L400 HydrophobicContact CZ-CD1 3.94Å; T396-L400 HydrophobicContact CG2-CD1 4Å; T396-L400 HydrophobicContact CG2-CG 4.45Å; T396-L400 WeakPolarHBondContact O-CB 3.42Å; T396-L400 VanDerWaalsContact O-CG 3.32Å; T396-L400 WeakPolarHBondContact O-CG 3.47Å; T396-L400 PolarHBondContact O-N 3.32Å; F397-L400 HydrophobicContact CD1-CD1 4.49Å; F397-L400 PolarHBondContact O-N 3.02Å; L400-S403 PolarHBondContact O-N 3.18Å; L400-L404 WeakPolarHBondContact O-CB 3.29Å; L400-L404 VanDerWaalsContact O-CG 3.28Å; L400-L404 WeakPolarHBondContact O-CG 3.42Å; L400-L404 PolarHBondContact O-N 3.08Å
401	S	94.6	Very high	90.5	Very high	2 Å²	2	29.2 Å²	29.2	1%	0.014	17%	0.167	C	C	.	.	H	α-helix	trans	-58.5	-56.8	177.3	-177.4	0	0	0	0	111.6	P377 L381 F397 L398 T399 S403 G405	P377-S401 VanDerWaalsContact CA-OG 3.32Å; P377-S401 WeakPolarHBondContact CA-OG 3.2Å; P377-S401 WeakPolarHBondContact CB-O 3.49Å; P377-S401 WeakPolarHBondContact CB-OG 3.36Å; P377-S401 VanDerWaalsContact CG-O 3.29Å; P377-S401 WeakPolarHBondContact CG-O 3.45Å; P377-S401 PolarHBondContact O-OG 2.88Å; L381-S401 WeakPolarHBondContact CG-OG 3.41Å; F397-S401 VanDerWaalsContact O-CB 3.28Å; F397-S401 WeakPolarHBondContact O-CB 3.22Å; F397-S401 PolarHBondContact O-N 3.15Å; L398-S401 PolarHBondContact O-N 3.34Å; T399-S401 VanDerWaalsContact C-N 3.28Å; T399-S401 PolarHBondContact O-N 3.02Å; S401-S403 VanDerWaalsContact C-N 3.33Å; S401-S403 PolarHBondContact O-N 2.75Å; S401-G405 PolarHBondContact O-N 2.83Å
402	T	91.2	Very high	90.8	Very high	13 Å²	13	26.8 Å²	26.8	8%	0.08	16%	0.156	C	C	.	.	H	α-helix	trans	-65.8	-38.7	-178.9	-48.1	0	0	0	0	111.6	L310 P336 Y337 L398 T399 G405 G406	L310-T402 VanDerWaalsContact CD1-OG1 3.3Å; L310-T402 WeakPolarHBondContact CD1-OG1 3.38Å; P336-T402 HydrophobicContact CB-CG2 3.97Å; P336-T402 WeakPolarHBondContact CB-OG1 3.35Å; Y337-T402 HydrophobicContact CD1-CG2 4.12Å; Y337-T402 HydrophobicContact CE1-CG2 4.04Å; L398-T402 PolarHBondContact O-N 3.1Å; L398-T402 VanDerWaalsContact O-N 3.14Å; L398-T402 PolarHBondContact O-OG1 3.45Å; L398-T402 VanDerWaalsContact O-OG1 3.1Å; T399-T402 PolarHBondContact O-N 2.88Å; T402-G405 PolarHBondContact O-N 3.34Å; T402-G406 PolarHBondContact O-N 3.32Å
403	S	92.3	Very high	90.7	Very high	8 Å²	8	23.5 Å²	23.5	6%	0.056	14%	0.135	C	C	.	.	H	α-helix	trans	-62.2	-50	-178.8	-58.7	0	0	0	0	111.6	C339 V343 T399 L400 S401 G405 G406	C339-S403 WeakPolarHBondContact CB-OG 3.38Å; V343-S403 VanDerWaalsContact CB-O 3.31Å; V343-S403 WeakPolarHBondContact CB-O 3.42Å; V343-S403 WeakPolarHBondContact CG1-O 3.48Å; T399-S403 WeakPolarHBondContact O-CB 3.44Å; T399-S403 PolarHBondContact O-N 2.93Å; T399-S403 PolarHBondContact O-OG 3.34Å; L400-S403 PolarHBondContact O-N 3.18Å; S401-S403 VanDerWaalsContact C-N 3.33Å; S401-S403 PolarHBondContact O-N 2.75Å; S403-G405 PolarHBondContact O-N 3.33Å; S403-G406 PolarHBondContact O-N 3.3Å
404	L	93.1	Very high	90.6	Very high	42 Å²	42	22.5 Å²	22.5	22%	0.22	13%	0.132	C	C	.	.	H	α-helix	trans	-67.5	-28.8	178.1	-68.6	168.9	0	0	0	112	L376 P377 F380 L400 G406 S407	L376-L404 HydrophobicContact CB-CB 4.28Å; L376-L404 HydrophobicContact CB-CD1 3.92Å; L376-L404 HydrophobicContact CD1-CD1 4.17Å; L376-L404 HydrophobicContact CD1-CD2 4.34Å; P377-L404 HydrophobicContact CG-CB 4.4Å; F380-L404 HydrophobicContact CD2-CD1 3.82Å; F380-L404 HydrophobicContact CE2-CD1 3.36Å; F380-L404 HydrophobicContact CZ-CD1 4.39Å; L400-L404 WeakPolarHBondContact O-CB 3.29Å; L400-L404 VanDerWaalsContact O-CG 3.28Å; L400-L404 WeakPolarHBondContact O-CG 3.42Å; L400-L404 PolarHBondContact O-N 3.08Å; L404-G406 PolarHBondContact O-N 3.5Å; L404-S407 WeakPolarHBondContact O-CB 3.39Å; L404-S407 PolarHBondContact O-N 2.92Å; L404-S407 PolarHBondContact O-OG 3.22Å
405	G	90.3	Very high	90.5	Very high	19 Å²	19	22.5 Å²	22.5	20%	0.196	13%	0.132	C	C	.	.	H	α-helix	trans	-57	-30.4	170.8	0	0	0	0	0	113	G373 S401 T402 S403 S407 S408	G373-G405 WeakPolarHBondContact O-CA 3.19Å; S401-G405 PolarHBondContact O-N 2.83Å; T402-G405 PolarHBondContact O-N 3.34Å; S403-G405 PolarHBondContact O-N 3.33Å; G405-S407 PolarHBondContact O-N 3.29Å; G405-S407 VanDerWaalsContact O-N 3.12Å; G405-S408 VanDerWaalsContact O-CB 3.24Å; G405-S408 WeakPolarHBondContact O-CB 3.13Å; G405-S408 PolarHBondContact O-N 3.19Å; G405-S408 PolarHBondContact O-OG 2.91Å; G405-S408 VanDerWaalsContact O-OG 3.09Å
406	G	87.4	Confident	90.3	Very high	14 Å²	14	22 Å²	22	14%	0.144	13%	0.128	C	C	.	.	G	3₁₀ helix	trans	-55.1	-25.9	172.1	0	0	0	0	0	114	S344 T402 S403 L404 S408 S409	S344-G406 WeakPolarHBondContact CA-O 3.24Å; S344-G406 WeakPolarHBondContact CB-O 3.23Å; T402-G406 PolarHBondContact O-N 3.32Å; S403-G406 PolarHBondContact O-N 3.3Å; L404-G406 PolarHBondContact O-N 3.5Å; G406-S408 PolarHBondContact O-N 3.42Å; G406-S408 VanDerWaalsContact O-N 3.16Å; G406-S409 VanDerWaalsContact O-CB 3.31Å; G406-S409 WeakPolarHBondContact O-CB 3.37Å; G406-S409 PolarHBondContact O-N 3.27Å; G406-S409 VanDerWaalsContact O-N 3.07Å; G406-S409 PolarHBondContact O-OG 3.03Å
407	S	90.6	Very high	89.8	Confident	11 Å²	11	23 Å²	23	8%	0.077	13%	0.13	C	C	.	.	G	3₁₀ helix	trans	-61.4	-23.2	176	-47.7	0	0	0	0	113.3	L404 G405 S409 A410	L404-S407 WeakPolarHBondContact O-CB 3.39Å; L404-S407 PolarHBondContact O-N 2.92Å; L404-S407 PolarHBondContact O-OG 3.22Å; G405-S407 PolarHBondContact O-N 3.29Å; G405-S407 VanDerWaalsContact O-N 3.12Å; S407-S409 PolarHBondContact O-N 2.95Å; S407-A410 PolarHBondContact O-N 2.89Å
408	S	90.4	Very high	89.3	Confident	0 Å²	0	22.4 Å²	22.4	0%	0	13%	0.129	C	C	.	.	G	3₁₀ helix	trans	-60.9	-23.8	175.9	-60.4	0	0	0	0	112.3	G373 G405 G406 A410 G411 V412 Y413	G373-S408 VanDerWaalsContact C-OG 3.29Å; G373-S408 WeakPolarHBondContact CA-OG 3.47Å; G373-S408 PolarHBondContact O-OG 3.46Å; G373-S408 VanDerWaalsContact O-OG 3.04Å; G405-S408 VanDerWaalsContact O-CB 3.24Å; G405-S408 WeakPolarHBondContact O-CB 3.13Å; G405-S408 PolarHBondContact O-N 3.19Å; G405-S408 PolarHBondContact O-OG 2.91Å; G405-S408 VanDerWaalsContact O-OG 3.09Å; G406-S408 PolarHBondContact O-N 3.42Å; G406-S408 VanDerWaalsContact O-N 3.16Å; S408-A410 VanDerWaalsContact C-N 3.28Å; S408-A410 PolarHBondContact O-N 3.44Å; S408-G411 CarbonylContact O-C 3.6Å; S408-G411 WeakPolarHBondContact O-CA 3.46Å; S408-G411 PolarHBondContact O-N 3.47Å; S408-V412 PolarHBondContact O-N 2.84Å; S408-Y413 WeakPolarHBondContact O-CD2 3.49Å
409	S	86.1	Confident	89	Confident	37 Å²	37	22.3 Å²	22.3	26%	0.259	13%	0.129	S	C	.	.	G	3₁₀ helix	trans	-56	-43.4	177	69.4	0	0	0	0	111.6	S344 S347 G406 S407 G411 V414	S344-S409 PolarHBondContact O-OG 3.31Å; S347-S409 PolarHBondContact OG-OG 3.16Å; G406-S409 VanDerWaalsContact O-CB 3.31Å; G406-S409 WeakPolarHBondContact O-CB 3.37Å; G406-S409 PolarHBondContact O-N 3.27Å; G406-S409 VanDerWaalsContact O-N 3.07Å; G406-S409 PolarHBondContact O-OG 3.03Å; S407-S409 PolarHBondContact O-N 2.95Å; S409-G411 VanDerWaalsContact C-N 3.27Å; S409-G411 PolarHBondContact O-N 3.47Å; S409-V414 VanDerWaalsContact O-CG2 3.28Å; S409-V414 WeakPolarHBondContact O-CG2 3.43Å
410	A	86.7	Confident	88.5	Confident	3 Å²	3	21.6 Å²	21.6	3%	0.025	12%	0.124	C	C	.	.	G	3₁₀ helix	trans	-81.1	-6.7	178.4	0	0	0	0	0	113.3	S347 A351 R366 F369 S407 S408	S347-A410 WeakPolarHBondContact O-CB 3.38Å; A351-A410 HydrophobicContact CB-CB 3.95Å; R366-A410 WeakPolarHBondContact CD-O 3.28Å; R366-A410 PolarHBondContact NH1-O 3.26Å; F369-A410 HydrophobicContact CB-CB 4.38Å; F369-A410 HydrophobicContact CD1-CB 4.2Å; F369-A410 HydrophobicContact CG-CB 4.12Å; S407-A410 PolarHBondContact O-N 2.89Å; S408-A410 VanDerWaalsContact C-N 3.28Å; S408-A410 PolarHBondContact O-N 3.44Å
411	G	90.4	Very high	87.5	Confident	0 Å²	0	22 Å²	22	0%	0	13%	0.13	C	C	.	.	T	Hydrogen-bonded Turn	trans	-100.6	-106.4	177.9	0	0	0	0	0	112	T370 S408 S409 Y413 N415	T370-G411 VanDerWaalsContact OG1-CA 3.29Å; T370-G411 WeakPolarHBondContact OG1-CA 3.22Å; S408-G411 CarbonylContact O-C 3.6Å; S408-G411 WeakPolarHBondContact O-CA 3.46Å; S408-G411 PolarHBondContact O-N 3.47Å; S409-G411 VanDerWaalsContact C-N 3.27Å; S409-G411 PolarHBondContact O-N 3.47Å; G411-Y413 PolarHBondContact O-N 2.93Å; G411-N415 PolarHBondContact O-N 3.37Å
412	V	89.4	Confident	86.4	Confident	0 Å²	0	27.1 Å²	27.1	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-62.2	-35.4	-171.6	66.9	0	0	0	0	113.8	I296 T299 Q300 T370 S408 V414 N415 Y476	I296-V412 HydrophobicContact CB-CG2 4.39Å; I296-V412 HydrophobicContact CG2-CG2 3.93Å; T299-V412 HydrophobicContact CG2-CB 4.21Å; T299-V412 HydrophobicContact CG2-CG1 4.49Å; T299-V412 HydrophobicContact CG2-CG2 3.97Å; Q300-V412 HydrophobicContact CB-CG2 4.4Å; T370-V412 HydrophobicContact CG2-CB 4.18Å; T370-V412 PolarHBondContact OG1-N 3.19Å; S408-V412 PolarHBondContact O-N 2.84Å; V412-V414 VanDerWaalsContact C-N 3.35Å; V412-V414 PolarHBondContact O-N 3.35Å; V412-N415 PolarHBondContact O-N 3.41Å; V412-Y476 HydrophobicContact CB-CE2 4.18Å; V412-Y476 HydrophobicContact CG2-CD2 4.34Å; V412-Y476 HydrophobicContact CG2-CE2 3.92Å
413	Y	86.3	Confident	85.5	Confident	68 Å²	68	27.5 Å²	27.5	27%	0.267	15%	0.15	S	C	.	.	H	α-helix	trans	-69	-30.1	-174.6	-76.7	-82.7	0	0	0	113.8	Q300 N304 S408 G411 Q416	Q300-Y413 HydrophobicContact CG-CD1 4.45Å; Q300-Y413 HydrophobicContact CG-CE1 3.84Å; Q300-Y413 VanDerWaalsContact NE2-CE1 3.31Å; N304-Y413 PolarHBondContact OD1-OH 2.91Å; S408-Y413 WeakPolarHBondContact O-CD2 3.49Å; G411-Y413 PolarHBondContact O-N 2.93Å; Y413-Q416 PolarHBondContact O-NE2 3.14Å
414	V	86.9	Confident	84.4	Confident	48 Å²	48	28 Å²	28	29%	0.291	15%	0.154	S	C	.	.	H	α-helix	trans	-90.2	-21.4	176.8	178.3	0	0	0	0	111.5	S409 V412 Q416 I417	S409-V414 VanDerWaalsContact O-CG2 3.28Å; S409-V414 WeakPolarHBondContact O-CG2 3.43Å; V412-V414 VanDerWaalsContact C-N 3.35Å; V412-V414 PolarHBondContact O-N 3.35Å; V414-Q416 PolarHBondContact O-N 2.82Å; V414-I417 WeakPolarHBondContact O-CB 3.06Å; V414-I417 PolarHBondContact O-N 3.44Å
415	N	88	Confident	83.2	Confident	0 Å²	0	29 Å²	29	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-59	-28.2	-174.3	-163.8	40.7	0	0	0	114	I296 G411 V412 I417 D418 I419 Y476 N481 G482	I296-N415 HydrophobicContact CD1-CB 4.06Å; I296-N415 WeakPolarHBondContact CD1-ND2 3.5Å; I296-N415 HydrophobicContact CG1-CB 4.23Å; I296-N415 WeakPolarHBondContact CG1-ND2 3.26Å; G411-N415 PolarHBondContact O-N 3.37Å; V412-N415 PolarHBondContact O-N 3.41Å; N415-I417 PolarHBondContact O-N 3Å; N415-D418 PolarHBondContact O-N 2.89Å; N415-D418 VanDerWaalsContact O-N 3.11Å; N415-I419 PolarHBondContact O-N 3.25Å; N415-Y476 WeakPolarHBondContact CB-OH 3.32Å; N415-Y476 VanDerWaalsContact CG-OH 3.22Å; N415-Y476 PolarHBondContact ND2-OH 3.43Å; N415-N481 PolarHBondContact ND2-O 3.3Å; N415-N481 PolarHBondContact OD1-O 3.38Å; N415-G482 WeakPolarHBondContact OD1-CA 3.19Å
416	Q	84.9	Confident	82.4	Confident	6 Å²	6	32 Å²	32	3%	0.028	18%	0.182	C	C	.	.	H	α-helix	trans	-61.1	-29.5	174.4	64.6	-165.7	-31.6	0	0	113.7	Y413 V414 I419 L427 T431	Y413-Q416 PolarHBondContact O-NE2 3.14Å; V414-Q416 PolarHBondContact O-N 2.82Å; Q416-I419 WeakPolarHBondContact O-CG1 3.43Å; Q416-L427 HydrophobicContact CB-CB 4.42Å; Q416-T431 PolarHBondContact OE1-OG1 3.32Å
417	I	83.4	Confident	82.1	Confident	86 Å²	86	31.3 Å²	31.3	44%	0.441	18%	0.175	S	C	.	.	H	α-helix	trans	-75.8	-38.2	175.3	-55.2	176.7	0	0	0	109.5	V414 N415 P421 A424	V414-I417 WeakPolarHBondContact O-CB 3.06Å; V414-I417 PolarHBondContact O-N 3.44Å; N415-I417 PolarHBondContact O-N 3Å; I417-P421 WeakPolarHBondContact O-CA 3.25Å; I417-P421 VanDerWaalsContact O-CD 3.3Å; I417-P421 WeakPolarHBondContact O-CD 3.48Å; I417-P421 VanDerWaalsContact O-CG 3.29Å; I417-P421 WeakPolarHBondContact O-CG 3.29Å; I417-A424 HydrophobicContact CG1-CB 4.17Å
418	D	83.8	Confident	81.5	Confident	31 Å²	31	33.6 Å²	33.6	17%	0.166	19%	0.187	C	C	.	.	H	α-helix	trans	-67.3	-35.7	-179.4	-59.1	-38.4	0	0	0	112.2	I362 R366 N415	I362-D418 HydrophobicContact CG2-CB 4.48Å; R366-D418 IonicContact CZ-OD2 2.97Å; R366-D418 VanDerWaalsContact CZ-OD2 3.29Å; R366-D418 IonicContact NE-OD2 3.23Å; R366-D418 PolarHBondContact NE-OD2 3.17Å; R366-D418 IonicContact NH2-OD1 2.86Å; R366-D418 PolarHBondContact NH2-OD1 3.47Å; R366-D418 IonicContact NH2-OD2 2.76Å; R366-D418 PolarHBondContact NH2-OD2 3.06Å; N415-D418 PolarHBondContact O-N 2.89Å; N415-D418 VanDerWaalsContact O-N 3.11Å
419	I	85.1	Confident	80.8	Confident	0 Å²	0	35.2 Å²	35.2	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-79.3	-31.2	-178.5	61.5	160.4	0	0	0	114	L293 I296 N415 Q416 L427 N481 I484 Q485	L293-I419 HydrophobicContact CB-CD1 4.42Å; L293-I419 HydrophobicContact CD1-CD1 4.22Å; I296-I419 HydrophobicContact CD1-CD1 3.57Å; I296-I419 HydrophobicContact CD1-CG1 4.08Å; I296-I419 HydrophobicContact CD1-CG2 4.26Å; N415-I419 PolarHBondContact O-N 3.25Å; Q416-I419 WeakPolarHBondContact O-CG1 3.43Å; I419-L427 HydrophobicContact CD1-CD1 3.96Å; I419-L427 HydrophobicContact CG1-CD1 4.15Å; I419-N481 WeakPolarHBondContact CG2-O 3.42Å; I419-I484 WeakPolarHBondContact O-CA 3.49Å; I419-Q485 HydrophobicContact CB-CG 4.07Å; I419-Q485 PolarHBondContact O-N 3.3Å
420	A	82.4	Confident	80.6	Confident	0 Å²	0	35.2 Å²	35.2	0%	0	20%	0.2	C	C	.	.			trans	-156.4	78.5	-177.1	0	0	0	0	0	112	R422 Y423 A424 L427 W487 A488	A420-R422 VanDerWaalsContact C-N 3.28Å; A420-R422 PolarHBondContact O-N 3.39Å; A420-Y423 HydrophobicContact CB-CD2 4.46Å; A420-Y423 CarbonylContact O-C 3.5Å; A420-Y423 PolarHBondContact O-N 2.88Å; A420-Y423 VanDerWaalsContact O-N 3.13Å; A420-A424 PolarHBondContact O-N 2.83Å; A420-L427 HydrophobicContact CB-CD1 3.78Å; A420-W487 HydrophobicContact CB-CH2 3.31Å; A420-W487 HydrophobicContact CB-CZ2 4.25Å; A420-W487 HydrophobicContact CB-CZ3 3.49Å; A420-W487 VanDerWaalsContact CB-CZ3 3.49Å; A420-A488 HydrophobicContact CB-CB 3.73Å
421	P	75.4	Confident	80.6	Confident	73 Å²	73	35.1 Å²	35.1	47%	0.474	20%	0.199	S	C	.	.	G	3₁₀ helix	trans	-55.5	-40.3	-178.7	-24.3	31.2	0	0	0	113.5	I417 Y423 A424	I417-P421 WeakPolarHBondContact O-CA 3.25Å; I417-P421 VanDerWaalsContact O-CD 3.3Å; I417-P421 WeakPolarHBondContact O-CD 3.48Å; I417-P421 VanDerWaalsContact O-CG 3.29Å; I417-P421 WeakPolarHBondContact O-CG 3.29Å; P421-Y423 VanDerWaalsContact C-N 3.28Å; P421-Y423 PolarHBondContact O-N 3.2Å; P421-A424 WeakPolarHBondContact O-CB 3.1Å; P421-A424 PolarHBondContact O-N 3.48Å
422	R	69.9	Low	80.3	Confident	110 Å²	110	36.9 Å²	36.9	42%	0.415	21%	0.208	S	C	.	.	G	3₁₀ helix	trans	-61.7	-33.7	-179.6	-177.3	173.9	171.3	175.6	-4.5	113.1	A420	A420-R422 VanDerWaalsContact C-N 3.28Å; A420-R422 PolarHBondContact O-N 3.39Å
423	Y	72.7	Confident	80.1	Confident	22 Å²	22	37.5 Å²	37.5	9%	0.086	21%	0.212	C	C	.	.	G	3₁₀ helix	trans	-109.3	10.7	-175.5	-55.3	-69.6	0	0	0	113	L282 M287 A420 P421 G425 F426 L427 W487 A488	L282-Y423 HydrophobicContact CD2-CD1 3.72Å; L282-Y423 HydrophobicContact CD2-CE1 3.91Å; M287-Y423 HydrophobicContact CE-CD1 4Å; M287-Y423 HydrophobicContact CE-CD2 3.67Å; M287-Y423 HydrophobicContact CE-CE2 4.34Å; M287-Y423 HydrophobicContact CE-CG 3.44Å; M287-Y423 VanDerWaalsContact CE-CG 3.44Å; A420-Y423 HydrophobicContact CB-CD2 4.46Å; A420-Y423 CarbonylContact O-C 3.5Å; A420-Y423 PolarHBondContact O-N 2.88Å; A420-Y423 VanDerWaalsContact O-N 3.13Å; P421-Y423 VanDerWaalsContact C-N 3.28Å; P421-Y423 PolarHBondContact O-N 3.2Å; Y423-G425 VanDerWaalsContact C-N 3.27Å; Y423-G425 PolarHBondContact O-N 2.96Å; Y423-G425 VanDerWaalsContact O-N 3.14Å; Y423-F426 PolarHBondContact O-N 2.97Å; Y423-L427 PolarHBondContact O-N 3.4Å; Y423-W487 HydrophobicContact CD2-CE3 4.09Å; Y423-W487 AromaticContact CD2-CZ3 3.65Å; Y423-W487 HydrophobicContact CD2-CZ3 3.65Å; Y423-W487 HydrophobicContact CE2-CE3 4.23Å; Y423-W487 HydrophobicContact CE2-CZ3 4.26Å; Y423-W487 HydrophobicContact CG-CZ3 4.44Å; Y423-A488 HydrophobicContact CD2-CB 4.45Å
424	A	69.9	Low	80.2	Confident	18 Å²	18	37.7 Å²	37.7	15%	0.149	21%	0.214	C	C	.	.	H	α-helix	trans	-54	-38.9	-172.2	0	0	0	0	0	113.7	I417 A420 P421 L428	I417-A424 HydrophobicContact CG1-CB 4.17Å; A420-A424 PolarHBondContact O-N 2.83Å; P421-A424 WeakPolarHBondContact O-CB 3.1Å; P421-A424 PolarHBondContact O-N 3.48Å; A424-L428 VanDerWaalsContact O-CB 3.24Å; A424-L428 WeakPolarHBondContact O-CB 3.06Å; A424-L428 PolarHBondContact O-N 3.2Å
425	G	67.2	Low	80.3	Confident	63 Å²	63	35.4 Å²	35.4	65%	0.649	20%	0.2	S	C	*	.	H	α-helix	trans	-66.6	-38.1	177.5	0	0	0	0	0	113.6	Y423 G429	Y423-G425 VanDerWaalsContact C-N 3.27Å; Y423-G425 PolarHBondContact O-N 2.96Å; Y423-G425 VanDerWaalsContact O-N 3.14Å; G425-G429 PolarHBondContact O-N 2.95Å
426	F	74.7	Confident	80.3	Confident	81 Å²	81	35.4 Å²	35.4	36%	0.355	20%	0.201	S	C	.	.	H	α-helix	trans	-72.2	-43.8	176.3	178.6	-108.4	0	0	0	111.2	L282 L284 M287 Y423 L428 G429 I430	L282-F426 HydrophobicContact CD1-CE1 4.5Å; L282-F426 HydrophobicContact CD1-CE2 4.31Å; L282-F426 HydrophobicContact CD1-CZ 4.28Å; L282-F426 HydrophobicContact CD2-CD1 4.14Å; L282-F426 HydrophobicContact CD2-CE1 4.37Å; L282-F426 HydrophobicContact CD2-CG 4.46Å; L284-F426 HydrophobicContact CD2-CE1 3.98Å; L284-F426 HydrophobicContact CD2-CZ 3.85Å; M287-F426 HydrophobicContact CE-CD1 4.32Å; M287-F426 HydrophobicContact SD-CD1 4.27Å; M287-F426 HydrophobicContact SD-CE1 4.08Å; Y423-F426 PolarHBondContact O-N 2.97Å; F426-L428 VanDerWaalsContact C-N 3.31Å; F426-L428 PolarHBondContact O-N 3.47Å; F426-G429 PolarHBondContact O-N 3.34Å; F426-G429 VanDerWaalsContact O-N 3.1Å; F426-I430 HydrophobicContact CD1-CD1 3.89Å; F426-I430 HydrophobicContact CE1-CD1 3.32Å; F426-I430 HydrophobicContact CE1-CG1 4.32Å; F426-I430 HydrophobicContact CE2-CD1 4.37Å; F426-I430 HydrophobicContact CZ-CD1 3.61Å; F426-I430 HydrophobicContact CZ-CG1 4.31Å; F426-I430 PolarHBondContact O-N 3Å
427	L	79.3	Confident	80.7	Confident	0 Å²	0	37.8 Å²	37.8	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-60	-41.8	174.8	-67.9	-170.6	0	0	0	111.9	M287 L293 Q416 I419 A420 Y423 G429 I430 T431 W487	M287-L427 HydrophobicContact CE-CD2 4.28Å; L293-L427 HydrophobicContact CD1-CD1 4.36Å; L293-L427 HydrophobicContact CD1-CD2 3.78Å; L293-L427 HydrophobicContact CD2-CD2 3.98Å; Q416-L427 HydrophobicContact CB-CB 4.42Å; I419-L427 HydrophobicContact CD1-CD1 3.96Å; I419-L427 HydrophobicContact CG1-CD1 4.15Å; A420-L427 HydrophobicContact CB-CD1 3.78Å; Y423-L427 PolarHBondContact O-N 3.4Å; L427-G429 VanDerWaalsContact C-N 3.27Å; L427-G429 PolarHBondContact O-N 3.07Å; L427-I430 PolarHBondContact O-N 3.31Å; L427-T431 WeakPolarHBondContact O-CB 3.5Å; L427-T431 WeakPolarHBondContact O-CG2 3.3Å; L427-T431 PolarHBondContact O-N 3.02Å; L427-T431 PolarHBondContact O-OG1 2.99Å; L427-W487 HydrophobicContact CD1-CH2 4.18Å; L427-W487 HydrophobicContact CD2-CH2 4.43Å
428	L	79	Confident	81.1	Confident	60 Å²	60	34 Å²	34	31%	0.314	19%	0.193	S	C	.	.	H	α-helix	trans	-59.1	-38.3	174.5	-178.7	67.4	0	0	0	112.1	M184 A424 F426 T431 N432	M184-L428 HydrophobicContact CE-CD2 4.1Å; A424-L428 VanDerWaalsContact O-CB 3.24Å; A424-L428 WeakPolarHBondContact O-CB 3.06Å; A424-L428 PolarHBondContact O-N 3.2Å; F426-L428 VanDerWaalsContact C-N 3.31Å; F426-L428 PolarHBondContact O-N 3.47Å; L428-T431 WeakPolarHBondContact CA-OG1 3.49Å; L428-T431 PolarHBondContact O-OG1 2.83Å; L428-N432 WeakPolarHBondContact O-CB 3.34Å; L428-N432 PolarHBondContact O-N 3.1Å
429	G	76	Confident	81.2	Confident	33 Å²	33	32.5 Å²	32.5	34%	0.34	19%	0.186	S	C	.	.	H	α-helix	trans	-64.1	-45.8	174.3	0	0	0	0	0	112.8	G425 F426 L427 T433	G425-G429 PolarHBondContact O-N 2.95Å; F426-G429 PolarHBondContact O-N 3.34Å; F426-G429 VanDerWaalsContact O-N 3.1Å; L427-G429 VanDerWaalsContact C-N 3.27Å; L427-G429 PolarHBondContact O-N 3.07Å; G429-T433 WeakPolarHBondContact O-CB 3.31Å; G429-T433 PolarHBondContact O-N 2.65Å; G429-T433 PolarHBondContact O-OG1 2.89Å
430	I	82.4	Confident	81.5	Confident	38 Å²	38	33.2 Å²	33.2	20%	0.195	19%	0.19	C	C	.	.	H	α-helix	trans	-63.4	-53.4	177.5	-68.8	175.1	0	0	0	110.5	I297 F426 L427 N432 T433 F434	I297-I430 HydrophobicContact CD1-CG2 3.95Å; F426-I430 HydrophobicContact CD1-CD1 3.89Å; F426-I430 HydrophobicContact CE1-CD1 3.32Å; F426-I430 HydrophobicContact CE1-CG1 4.32Å; F426-I430 HydrophobicContact CE2-CD1 4.37Å; F426-I430 HydrophobicContact CZ-CD1 3.61Å; F426-I430 HydrophobicContact CZ-CG1 4.31Å; F426-I430 PolarHBondContact O-N 3Å; L427-I430 PolarHBondContact O-N 3.31Å; I430-N432 VanDerWaalsContact C-N 3.29Å; I430-N432 PolarHBondContact O-N 3.14Å; I430-T433 WeakPolarHBondContact O-CB 3.48Å; I430-T433 PolarHBondContact O-N 3.42Å; I430-T433 VanDerWaalsContact O-N 3.09Å; I430-F434 HydrophobicContact CG2-CD2 3.79Å; I430-F434 HydrophobicContact CG2-CE2 3.87Å; I430-F434 WeakPolarHBondContact O-CD2 3.45Å; I430-F434 PolarHBondContact O-N 3.08Å
431	T	86.2	Confident	82	Confident	0 Å²	0	36 Å²	36	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-63	-37.2	-175.7	60.6	0	0	0	0	111.2	L293 I296 I297 Q416 L427 L428 G435	L293-T431 HydrophobicContact CD1-CG2 4.45Å; I296-T431 HydrophobicContact CG2-CG2 4.22Å; I297-T431 HydrophobicContact CG1-CG2 3.83Å; Q416-T431 PolarHBondContact OE1-OG1 3.32Å; L427-T431 WeakPolarHBondContact O-CB 3.5Å; L427-T431 WeakPolarHBondContact O-CG2 3.3Å; L427-T431 PolarHBondContact O-N 3.02Å; L427-T431 PolarHBondContact O-OG1 2.99Å; L428-T431 WeakPolarHBondContact CA-OG1 3.49Å; L428-T431 PolarHBondContact O-OG1 2.83Å; T431-G435 WeakPolarHBondContact O-CA 3.3Å; T431-G435 PolarHBondContact O-N 3.41Å
432	N	84.3	Confident	82.7	Confident	38 Å²	38	32.5 Å²	32.5	20%	0.203	18%	0.184	C	C	.	.	H	α-helix	trans	-70	-36.1	174.2	-164.5	52.6	0	0	0	112.8	Q124 L428 I430 G435 T436	Q124-N432 PolarHBondContact OE1-ND2 2.89Å; L428-N432 WeakPolarHBondContact O-CB 3.34Å; L428-N432 PolarHBondContact O-N 3.1Å; I430-N432 VanDerWaalsContact C-N 3.29Å; I430-N432 PolarHBondContact O-N 3.14Å; N432-G435 PolarHBondContact O-N 3.5Å; N432-T436 VanDerWaalsContact O-CG2 3.23Å; N432-T436 WeakPolarHBondContact O-CG2 3.4Å; N432-T436 PolarHBondContact O-N 2.84Å; N432-T436 VanDerWaalsContact O-N 3.09Å; N432-T436 PolarHBondContact O-OG1 3.36Å
433	T	84.8	Confident	83.7	Confident	12 Å²	12	27.3 Å²	27.3	7%	0.074	17%	0.165	C	C	.	.	H	α-helix	trans	-62.3	-55.4	176.6	-58.5	0	0	0	0	110.5	L121 I125 G429 I430 G435 T436	L121-T433 HydrophobicContact CD1-CG2 4.44Å; L121-T433 HydrophobicContact CG-CG2 4.47Å; I125-T433 HydrophobicContact CD1-CG2 3.94Å; I125-T433 HydrophobicContact CG1-CG2 4.09Å; G429-T433 WeakPolarHBondContact O-CB 3.31Å; G429-T433 PolarHBondContact O-N 2.65Å; G429-T433 PolarHBondContact O-OG1 2.89Å; I430-T433 WeakPolarHBondContact O-CB 3.48Å; I430-T433 PolarHBondContact O-N 3.42Å; I430-T433 VanDerWaalsContact O-N 3.09Å; T433-G435 VanDerWaalsContact C-N 3.29Å; T433-G435 PolarHBondContact O-N 3.48Å; T433-T436 PolarHBondContact O-N 2.97Å; T433-T436 VanDerWaalsContact O-N 3.15Å; T433-T436 PolarHBondContact O-OG1 3.47Å
434	F	89	Confident	84.5	Confident	72 Å²	72	27.8 Å²	27.8	32%	0.316	17%	0.169	S	C	.	.	H	α-helix	trans	-62.7	-39	175.8	-76.2	-78.2	0	0	0	111.9	W294 I297 M301 I430 T436 I437	W294-F434 HydrophobicContact CH2-CZ 4.4Å; I297-F434 HydrophobicContact CG2-CB 3.55Å; I297-F434 HydrophobicContact CG2-CD1 4.5Å; I297-F434 HydrophobicContact CG2-CD2 4.23Å; I297-F434 HydrophobicContact CG2-CG 3.86Å; M301-F434 HydrophobicContact CG-CB 4.39Å; M301-F434 WeakPolarHBondContact CG-O 3Å; M301-F434 HydrophobicContact SD-CB 4.06Å; I430-F434 HydrophobicContact CG2-CD2 3.79Å; I430-F434 HydrophobicContact CG2-CE2 3.87Å; I430-F434 WeakPolarHBondContact O-CD2 3.45Å; I430-F434 PolarHBondContact O-N 3.08Å; F434-T436 PolarHBondContact O-N 3.41Å; F434-T436 VanDerWaalsContact O-N 3.09Å; F434-I437 HydrophobicContact CB-CD1 4.45Å; F434-I437 HydrophobicContact CD1-CD1 3.7Å; F434-I437 HydrophobicContact CE1-CD1 4.45Å; F434-I437 HydrophobicContact CG-CD1 4.48Å; F434-I437 WeakPolarHBondContact O-CB 3.24Å; F434-I437 WeakPolarHBondContact O-CG1 3.36Å; F434-I437 PolarHBondContact O-N 3.42Å; F434-I437 VanDerWaalsContact O-N 3.09Å
435	G	88.6	Confident	85.6	Confident	0 Å²	0	28.8 Å²	28.8	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-60	-18.4	176.4	0	0	0	0	0	114.3	N304 T431 N432 T433 P438	N304-G435 VanDerWaalsContact CB-O 3.25Å; N304-G435 WeakPolarHBondContact CB-O 3.32Å; N304-G435 PolarHBondContact ND2-O 3.38Å; T431-G435 WeakPolarHBondContact O-CA 3.3Å; T431-G435 PolarHBondContact O-N 3.41Å; N432-G435 PolarHBondContact O-N 3.5Å; T433-G435 VanDerWaalsContact C-N 3.29Å; T433-G435 PolarHBondContact O-N 3.48Å; G435-P438 WeakPolarHBondContact O-CD 3.38Å
436	T	88.3	Confident	86.6	Confident	1 Å²	1	26.1 Å²	26.1	1%	0.006	14%	0.144	C	C	.	.	H	α-helix	trans	-91.9	-10.6	176.7	58.2	0	0	0	0	115	Y120 Q124 N432 T433 F434 P438 G439	Y120-T436 HydrophobicContact CD1-CG2 3.93Å; Y120-T436 HydrophobicContact CE1-CG2 3.59Å; Q124-T436 PolarHBondContact NE2-OG1 3.02Å; Q124-T436 VanDerWaalsContact NE2-OG1 3.14Å; N432-T436 VanDerWaalsContact O-CG2 3.23Å; N432-T436 WeakPolarHBondContact O-CG2 3.4Å; N432-T436 PolarHBondContact O-N 2.84Å; N432-T436 VanDerWaalsContact O-N 3.09Å; N432-T436 PolarHBondContact O-OG1 3.36Å; T433-T436 PolarHBondContact O-N 2.97Å; T433-T436 VanDerWaalsContact O-N 3.15Å; T433-T436 PolarHBondContact O-OG1 3.47Å; F434-T436 PolarHBondContact O-N 3.41Å; F434-T436 VanDerWaalsContact O-N 3.09Å; T436-P438 VanDerWaalsContact C-CD 3.47Å; T436-G439 WeakPolarHBondContact O-CA 3.28Å; T436-G439 PolarHBondContact O-N 3.39Å
437	I	91.5	Very high	87.2	Confident	56 Å²	56	22.4 Å²	22.4	29%	0.287	13%	0.129	S	C	.	.	H	α-helix	trans	-55.1	-43.9	174.4	-63.2	169.4	0	0	0	112.3	L121 M301 F434 G439 V440 V441	L121-I437 HydrophobicContact CD1-CG1 3.55Å; M301-I437 HydrophobicContact CE-CB 4.19Å; M301-I437 HydrophobicContact CE-CD1 4.16Å; M301-I437 HydrophobicContact CE-CG2 4.33Å; F434-I437 HydrophobicContact CB-CD1 4.45Å; F434-I437 HydrophobicContact CD1-CD1 3.7Å; F434-I437 HydrophobicContact CE1-CD1 4.45Å; F434-I437 HydrophobicContact CG-CD1 4.48Å; F434-I437 WeakPolarHBondContact O-CB 3.24Å; F434-I437 WeakPolarHBondContact O-CG1 3.36Å; F434-I437 PolarHBondContact O-N 3.42Å; F434-I437 VanDerWaalsContact O-N 3.09Å; I437-G439 PolarHBondContact O-N 3.34Å; I437-G439 VanDerWaalsContact O-N 3.14Å; I437-V440 WeakPolarHBondContact O-CB 3.2Å; I437-V440 PolarHBondContact O-N 3.02Å; I437-V441 HydrophobicContact CG2-CG2 4.25Å; I437-V441 PolarHBondContact O-N 3.03Å
438	P	92.1	Very high	87.6	Confident	5 Å²	5	29.6 Å²	29.6	3%	0.032	16%	0.157	C	C	.	.	H	α-helix	trans	-57.4	-27.2	174.9	-23.1	32.9	0	0	0	113.8	M301 N304 W305 Y308 G435 T436 V440 V441 A442	M301-P438 HydrophobicContact CB-CG 4.11Å; M301-P438 VanDerWaalsContact O-CG 3.22Å; M301-P438 WeakPolarHBondContact O-CG 3.29Å; N304-P438 HydrophobicContact CB-CG 4.3Å; W305-P438 HydrophobicContact CB-CB 3.97Å; W305-P438 HydrophobicContact CE3-CB 3.92Å; Y308-P438 HydrophobicContact CD2-CB 4.35Å; G435-P438 WeakPolarHBondContact O-CD 3.38Å; T436-P438 VanDerWaalsContact C-CD 3.47Å; P438-V440 PolarHBondContact O-N 2.95Å; P438-V441 PolarHBondContact O-N 3.37Å; P438-A442 WeakPolarHBondContact O-CB 3.3Å; P438-A442 PolarHBondContact O-N 2.91Å
439	G	87.3	Confident	88.1	Confident	0 Å²	0	29.2 Å²	29.2	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-65	-28.5	175.2	0	0	0	0	0	113.2	F117 T436 I437 P443	F117-G439 WeakPolarHBondContact CD2-O 3.49Å; F117-G439 WeakPolarHBondContact CE2-O 3.29Å; F117-G439 VanDerWaalsContact CG-C 3.45Å; T436-G439 WeakPolarHBondContact O-CA 3.28Å; T436-G439 PolarHBondContact O-N 3.39Å; I437-G439 PolarHBondContact O-N 3.34Å; I437-G439 VanDerWaalsContact O-N 3.14Å; G439-P443 WeakPolarHBondContact O-CD 3.33Å; G439-P443 VanDerWaalsContact O-CG 3.29Å; G439-P443 WeakPolarHBondContact O-CG 3.28Å
440	V	90.3	Very high	88.5	Confident	15 Å²	15	28 Å²	28	9%	0.091	14%	0.138	C	C	.	.	H	α-helix	trans	-76.4	-51.1	172.7	-178.9	0	0	0	0	110.5	F117 F118 I437 P438 I444	F117-V440 HydrophobicContact CB-CB 4.29Å; F117-V440 HydrophobicContact CB-CG2 3.39Å; F118-V440 HydrophobicContact CD1-CG1 4.16Å; F118-V440 HydrophobicContact CD2-CG1 3.84Å; F118-V440 HydrophobicContact CE1-CG1 3.72Å; F118-V440 HydrophobicContact CE2-CG1 3.38Å; F118-V440 HydrophobicContact CG-CG1 4.22Å; F118-V440 HydrophobicContact CZ-CG1 3.31Å; I437-V440 WeakPolarHBondContact O-CB 3.2Å; I437-V440 PolarHBondContact O-N 3.02Å; P438-V440 PolarHBondContact O-N 2.95Å; V440-I444 HydrophobicContact CG1-CD1 4.22Å; V440-I444 VanDerWaalsContact O-CD1 3.26Å; V440-I444 WeakPolarHBondContact O-CD1 3.32Å; V440-I444 WeakPolarHBondContact O-CG1 3.47Å
441	V	92.4	Very high	88.3	Confident	59 Å²	59	32 Å²	32	36%	0.358	16%	0.156	S	C	.	.	H	α-helix	trans	-79.7	-37.3	-166.2	-174.7	0	0	0	0	112	W305 I437 P438 I444 V445	W305-V441 HydrophobicContact CH2-CB 4.24Å; W305-V441 HydrophobicContact CH2-CG1 3.73Å; W305-V441 HydrophobicContact CZ3-CB 3.8Å; W305-V441 HydrophobicContact CZ3-CG1 3.66Å; I437-V441 HydrophobicContact CG2-CG2 4.25Å; I437-V441 PolarHBondContact O-N 3.03Å; P438-V441 PolarHBondContact O-N 3.37Å; V441-I444 PolarHBondContact O-N 3.06Å; V441-V445 HydrophobicContact CG1-CG2 3.88Å; V441-V445 WeakPolarHBondContact O-CB 3.18Å; V441-V445 WeakPolarHBondContact O-CG2 3.31Å; V441-V445 PolarHBondContact O-N 2.86Å
442	A	91.9	Very high	87.7	Confident	0 Å²	0	37 Å²	37	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-64.1	-44.3	-174.1	0	0	0	0	0	114.1	W305 T309 P438 I444 V445 T446	W305-A442 HydrophobicContact CD2-CB 4.1Å; W305-A442 HydrophobicContact CE3-CB 4.3Å; W305-A442 HydrophobicContact CH2-CB 4.32Å; W305-A442 HydrophobicContact CZ2-CB 4.12Å; W305-A442 HydrophobicContact CZ3-CB 4.41Å; T309-A442 WeakPolarHBondContact OG1-CB 3.41Å; P438-A442 WeakPolarHBondContact O-CB 3.3Å; P438-A442 PolarHBondContact O-N 2.91Å; A442-I444 VanDerWaalsContact C-N 3.35Å; A442-I444 PolarHBondContact O-N 3.36Å; A442-V445 PolarHBondContact O-N 3.24Å; A442-T446 WeakPolarHBondContact O-CB 3.27Å; A442-T446 PolarHBondContact O-N 3.36Å; A442-T446 PolarHBondContact O-OG1 3.3Å
443	P	89.4	Confident	87.3	Confident	1 Å²	1	38.9 Å²	38.9	1%	0.006	19%	0.191	C	C	.	.	H	α-helix	trans	-64	-38.5	175.8	-22.1	34.2	0	0	0	112.6	G110 L113 T312 G439 T446 G447	G110-P443 WeakPolarHBondContact CA-O 3.21Å; G110-P443 WeakPolarHBondContact O-CB 3.44Å; L113-P443 HydrophobicContact CB-CB 3.93Å; T312-P443 HydrophobicContact CG2-CG 3.97Å; G439-P443 WeakPolarHBondContact O-CD 3.33Å; G439-P443 VanDerWaalsContact O-CG 3.29Å; G439-P443 WeakPolarHBondContact O-CG 3.28Å; P443-T446 PolarHBondContact O-N 3.34Å; P443-G447 PolarHBondContact O-N 3.48Å
444	I	90.8	Very high	87	Confident	32 Å²	32	39.3 Å²	39.3	16%	0.164	19%	0.193	C	C	.	.	H	α-helix	trans	-64.7	-48.6	178.1	-61.1	170.1	0	0	0	110.4	W111 F118 V440 V441 A442 T446 G447 Y448	W111-I444 HydrophobicContact CD2-CD1 4.15Å; W111-I444 HydrophobicContact CD2-CG1 4.2Å; W111-I444 HydrophobicContact CE3-CD1 3.72Å; W111-I444 HydrophobicContact CE3-CG1 4.21Å; W111-I444 HydrophobicContact CH2-CD1 4.06Å; W111-I444 HydrophobicContact CZ2-CD1 4.45Å; W111-I444 HydrophobicContact CZ2-CG2 4.23Å; W111-I444 HydrophobicContact CZ3-CD1 3.68Å; F118-I444 HydrophobicContact CE2-CD1 4.37Å; V440-I444 HydrophobicContact CG1-CD1 4.22Å; V440-I444 VanDerWaalsContact O-CD1 3.26Å; V440-I444 WeakPolarHBondContact O-CD1 3.32Å; V440-I444 WeakPolarHBondContact O-CG1 3.47Å; V441-I444 PolarHBondContact O-N 3.06Å; A442-I444 VanDerWaalsContact C-N 3.35Å; A442-I444 PolarHBondContact O-N 3.36Å; I444-T446 VanDerWaalsContact C-N 3.27Å; I444-T446 PolarHBondContact O-N 3.19Å; I444-G447 PolarHBondContact O-N 3.2Å; I444-Y448 PolarHBondContact O-N 2.94Å
445	V	91.8	Very high	86.5	Confident	39 Å²	39	36.5 Å²	36.5	24%	0.236	18%	0.181	C	C	.	.	H	α-helix	trans	-62.9	-37.2	176.9	170.5	0	0	0	0	111.2	W305 V441 A442 F449	W305-V445 HydrophobicContact CH2-CB 4.28Å; W305-V445 HydrophobicContact CH2-CG2 4.07Å; W305-V445 HydrophobicContact CZ2-CB 4.34Å; W305-V445 HydrophobicContact CZ2-CG1 4.29Å; V441-V445 HydrophobicContact CG1-CG2 3.88Å; V441-V445 WeakPolarHBondContact O-CB 3.18Å; V441-V445 WeakPolarHBondContact O-CG2 3.31Å; V441-V445 PolarHBondContact O-N 2.86Å; A442-V445 PolarHBondContact O-N 3.24Å; V445-F449 HydrophobicContact CG1-CD2 3.67Å; V445-F449 HydrophobicContact CG1-CE2 3.35Å; V445-F449 HydrophobicContact CG1-CZ 4.29Å; V445-F449 VanDerWaalsContact O-CD2 3.27Å; V445-F449 WeakPolarHBondContact O-CD2 3.32Å; V445-F449 PolarHBondContact O-N 2.98Å; V445-F449 VanDerWaalsContact O-N 3.14Å
446	T	89.3	Confident	86.3	Confident	6 Å²	6	38.3 Å²	38.3	4%	0.037	20%	0.196	C	C	.	.	H	α-helix	trans	-62.5	-51.6	174.8	-57	0	0	0	0	110.6	A442 P443 I444 Y448 F449 T450 W458 V461	A442-T446 WeakPolarHBondContact O-CB 3.27Å; A442-T446 PolarHBondContact O-N 3.36Å; A442-T446 PolarHBondContact O-OG1 3.3Å; P443-T446 PolarHBondContact O-N 3.34Å; I444-T446 VanDerWaalsContact C-N 3.27Å; I444-T446 PolarHBondContact O-N 3.19Å; T446-Y448 VanDerWaalsContact C-N 3.3Å; T446-Y448 PolarHBondContact O-N 3.34Å; T446-F449 PolarHBondContact O-N 3.43Å; T446-T450 HydrophobicContact CG2-CG2 4.13Å; T446-T450 WeakPolarHBondContact O-CG2 3.21Å; T446-T450 PolarHBondContact O-N 3.2Å; T446-T450 PolarHBondContact O-OG1 2.94Å; T446-W458 HydrophobicContact CG2-CH2 3.84Å; T446-W458 HydrophobicContact CG2-CZ3 3.79Å; T446-V461 HydrophobicContact CG2-CG1 4.11Å; T446-V461 HydrophobicContact CG2-CG2 4.12Å
447	G	86.1	Confident	86.2	Confident	4 Å²	4	38.3 Å²	38.3	4%	0.041	20%	0.197	C	C	.	.	H	α-helix	trans	-56.7	-40.9	179.5	0	0	0	0	0	113.3	S106 P443 I444 T450 E451	S106-G447 WeakPolarHBondContact CB-O 3.47Å; S106-G447 VanDerWaalsContact O-CA 3.22Å; S106-G447 WeakPolarHBondContact O-CA 3.25Å; P443-G447 PolarHBondContact O-N 3.48Å; I444-G447 PolarHBondContact O-N 3.2Å; G447-T450 PolarHBondContact O-N 3.37Å; G447-E451 PolarHBondContact O-N 3.4Å
448	Y	89.3	Confident	86	Confident	150 Å²	150	35.9 Å²	35.9	59%	0.588	18%	0.184	S	C	*	.	H	α-helix	trans	-64.5	-40.3	175.4	-179.5	-98.8	0	0	0	113	I444 T446 T450	I444-Y448 PolarHBondContact O-N 2.94Å; T446-Y448 VanDerWaalsContact C-N 3.3Å; T446-Y448 PolarHBondContact O-N 3.34Å; Y448-T450 VanDerWaalsContact C-N 3.35Å
449	F	88.7	Confident	86	Confident	53 Å²	53	39.3 Å²	39.3	23%	0.232	20%	0.196	C	C	.	.	H	α-helix	trans	-78.2	-18.7	179.2	-71.2	-40.2	0	0	0	114.1	V445 T446 G457 K460 V461 V464	V445-F449 HydrophobicContact CG1-CD2 3.67Å; V445-F449 HydrophobicContact CG1-CE2 3.35Å; V445-F449 HydrophobicContact CG1-CZ 4.29Å; V445-F449 VanDerWaalsContact O-CD2 3.27Å; V445-F449 WeakPolarHBondContact O-CD2 3.32Å; V445-F449 PolarHBondContact O-N 2.98Å; V445-F449 VanDerWaalsContact O-N 3.14Å; T446-F449 PolarHBondContact O-N 3.43Å; F449-G457 WeakPolarHBondContact O-CA 3.36Å; F449-K460 HydrophobicContact CD1-CB 4.44Å; F449-K460 HydrophobicContact CD1-CD 4.08Å; F449-K460 HydrophobicContact CD2-CB 4.37Å; F449-K460 HydrophobicContact CE1-CD 4.49Å; F449-K460 HydrophobicContact CG-CB 4.23Å; F449-V461 HydrophobicContact CB-CG2 3.75Å; F449-V461 HydrophobicContact CD2-CG2 4.13Å; F449-V461 HydrophobicContact CG-CG2 4.44Å; F449-V464 HydrophobicContact CE2-CG2 4.03Å
450	T	84.8	Confident	86.2	Confident	6 Å²	6	44.7 Å²	44.7	4%	0.037	22%	0.219	C	C	.	.	T	Hydrogen-bonded Turn	trans	-105.2	17.9	-176.5	62.7	0	0	0	0	113.3	S106 T446 G447 Y448 D452 H453 W458 V461	S106-T450 PolarHBondContact OG-O 3.22Å; S106-T450 VanDerWaalsContact OG-O 3.12Å; T446-T450 HydrophobicContact CG2-CG2 4.13Å; T446-T450 WeakPolarHBondContact O-CG2 3.21Å; T446-T450 PolarHBondContact O-N 3.2Å; T446-T450 PolarHBondContact O-OG1 2.94Å; G447-T450 PolarHBondContact O-N 3.37Å; Y448-T450 VanDerWaalsContact C-N 3.35Å; T450-D452 VanDerWaalsContact C-N 3.26Å; T450-D452 PolarHBondContact O-N 2.83Å; T450-H453 PolarHBondContact O-N 3Å; T450-H453 VanDerWaalsContact O-N 3.08Å; T450-W458 HydrophobicContact CG2-CD2 3.65Å; T450-W458 VanDerWaalsContact CG2-CE2 3.44Å; T450-W458 HydrophobicContact CG2-CE3 4.17Å; T450-W458 HydrophobicContact CG2-CG 4.04Å; T450-W458 HydrophobicContact CG2-CH2 4.31Å; T450-W458 HydrophobicContact CG2-CZ2 3.81Å; T450-W458 HydrophobicContact CG2-CZ3 4.47Å; T450-V461 HydrophobicContact CG2-CG2 4.09Å
451	E	78.4	Confident	86.3	Confident	123 Å²	123	44.2 Å²	44.2	58%	0.575	22%	0.217	S	C	*	.	T	Hydrogen-bonded Turn	trans	-54.9	-41.2	176	-167.4	-177.5	173.8	0	0	112.1	G447 H453	G447-E451 PolarHBondContact O-N 3.4Å; E451-H453 VanDerWaalsContact C-N 3.26Å; E451-H453 PolarHBondContact O-CD2 3Å; E451-H453 PolarHBondContact O-N 2.58Å
452	D	73.6	Confident	86.4	Confident	104 Å²	104	41.7 Å²	41.7	56%	0.556	20%	0.201	S	C	*	.	T	Hydrogen-bonded Turn	trans	-79.2	-2.5	-178.7	-58.4	-47.7	0	0	0	113.8	T450 T454	T450-D452 VanDerWaalsContact C-N 3.26Å; T450-D452 PolarHBondContact O-N 2.83Å; D452-T454 HydrophobicContact CB-CG2 3.94Å; D452-T454 WeakPolarHBondContact O-CG2 3.36Å; D452-T454 PolarHBondContact O-N 3.29Å
453	H	74.2	Confident	86.5	Confident	79 Å²	79	47.5 Å²	47.5	37%	0.366	22%	0.223	S	C	.	.			trans	48.5	28.5	-171.3	-60.9	-86.3	0	0	0	114.6	S106 D320 T450 E451	S106-H453 PolarHBondContact OG-CE1 3.01Å; S106-H453 PolarHBondContact OG-NE2 3.05Å; D320-H453 IonicContact OD2-CE1 3.91Å; D320-H453 IonicContact OD2-ND1 2.66Å; D320-H453 PolarHBondContact OD2-ND1 3.27Å; T450-H453 PolarHBondContact O-N 3Å; T450-H453 VanDerWaalsContact O-N 3.08Å; E451-H453 VanDerWaalsContact C-N 3.26Å; E451-H453 PolarHBondContact O-CD2 3Å; E451-H453 PolarHBondContact O-N 2.58Å
454	T	79.1	Confident	86.8	Confident	21 Å²	21	49.9 Å²	49.9	13%	0.129	24%	0.237	C	C	.	.			trans	-98.7	156.4	-177.7	60.3	0	0	0	0	113.1	A76 D452 A456 G457 W458	A76-T454 HydrophobicContact CB-CG2 4.07Å; D452-T454 HydrophobicContact CB-CG2 3.94Å; D452-T454 WeakPolarHBondContact O-CG2 3.36Å; D452-T454 PolarHBondContact O-N 3.29Å; T454-A456 PolarHBondContact O-N 3Å; T454-G457 PolarHBondContact O-N 3.4Å; T454-G457 VanDerWaalsContact O-N 3.13Å; T454-G457 PolarHBondContact OG1-N 3.38Å; T454-W458 PolarHBondContact O-N 2.79Å
455	M	79.6	Confident	86.9	Confident	12 Å²	12	48.5 Å²	48.5	6%	0.059	23%	0.23	C	C	.	.	H	α-helix	trans	-53.6	-36.1	168.5	-82.2	-75.1	-108.8	0	0	112.5	I321 G388 G457 W458 R459	I321-M455 HydrophobicContact CD1-CG 4.26Å; I321-M455 HydrophobicContact CD1-SD 4.42Å; I321-M455 HydrophobicContact CG2-CE 4.29Å; I321-M455 HydrophobicContact CG2-CG 4.12Å; I321-M455 HydrophobicContact CG2-SD 3.22Å; I321-M455 WeakPolarHBondContact CG2-SD 3.32Å; G388-M455 WeakPolarHBondContact O-CE 3.3Å; M455-G457 VanDerWaalsContact C-N 3.35Å; M455-G457 PolarHBondContact O-N 3.39Å; M455-W458 PolarHBondContact O-N 3.26Å; M455-R459 WeakPolarHBondContact O-CG 3.42Å; M455-R459 PolarHBondContact O-N 3.09Å
456	A	83.9	Confident	87.1	Confident	38 Å²	38	46.6 Å²	46.6	31%	0.314	22%	0.219	S	C	.	.	H	α-helix	trans	-65.5	-36.3	179.5	0	0	0	0	0	112.8	T454 K460	T454-A456 PolarHBondContact O-N 3Å; A456-K460 PolarHBondContact O-N 3.11Å
457	G	85.8	Confident	87.4	Confident	2 Å²	2	48.4 Å²	48.4	2%	0.021	24%	0.239	C	C	.	.	H	α-helix	trans	-62.3	-51.2	173.9	0	0	0	0	0	111.8	F449 T454 M455 R459 K460 V461	F449-G457 WeakPolarHBondContact O-CA 3.36Å; T454-G457 PolarHBondContact O-N 3.4Å; T454-G457 VanDerWaalsContact O-N 3.13Å; T454-G457 PolarHBondContact OG1-N 3.38Å; M455-G457 VanDerWaalsContact C-N 3.35Å; M455-G457 PolarHBondContact O-N 3.39Å; G457-R459 VanDerWaalsContact C-N 3.32Å; G457-R459 PolarHBondContact O-N 3.32Å; G457-K460 WeakPolarHBondContact O-CB 3.13Å; G457-K460 PolarHBondContact O-N 3.41Å; G457-V461 PolarHBondContact O-N 3.44Å
458	W	88.4	Confident	87.9	Confident	5 Å²	5	50.5 Å²	50.5	2%	0.019	25%	0.249	C	C	.	.	H	α-helix	trans	-63.6	-33.9	177.9	-75.7	101.2	0	0	0	113.9	S313 T316 Y317 I321 T446 T450 T454 M455 K460 V461 F462	S313-W458 VanDerWaalsContact O-CH2 3.3Å; S313-W458 WeakPolarHBondContact O-CH2 3.06Å; T316-W458 HydrophobicContact CG2-CZ2 4.22Å; Y317-W458 HydrophobicContact CD2-CB 4.09Å; Y317-W458 AromaticContact CD2-CD2 3.44Å; Y317-W458 HydrophobicContact CD2-CD2 3.44Å; Y317-W458 VanDerWaalsContact CD2-CD2 3.44Å; Y317-W458 AromaticContact CD2-CE2 3.82Å; Y317-W458 AromaticContact CD2-CE3 3.72Å; Y317-W458 HydrophobicContact CD2-CE3 3.72Å; Y317-W458 AromaticContact CD2-CG 3.61Å; Y317-W458 HydrophobicContact CD2-CG 3.61Å; Y317-W458 HydrophobicContact CD2-CZ2 4.4Å; Y317-W458 HydrophobicContact CD2-CZ3 4.31Å; Y317-W458 HydrophobicContact CE2-CB 3.96Å; Y317-W458 HydrophobicContact CE2-CD2 4.22Å; Y317-W458 AromaticContact CE2-CG 3.96Å; Y317-W458 HydrophobicContact CE2-CG 3.96Å; Y317-W458 HydrophobicContact CG-CD2 4.31Å; Y317-W458 HydrophobicContact CG-CE3 4.28Å; Y317-W458 HydrophobicContact CG-CZ3 4.46Å; I321-W458 HydrophobicContact CG1-CG 4.13Å; T446-W458 HydrophobicContact CG2-CH2 3.84Å; T446-W458 HydrophobicContact CG2-CZ3 3.79Å; T450-W458 HydrophobicContact CG2-CD2 3.65Å; T450-W458 VanDerWaalsContact CG2-CE2 3.44Å; T450-W458 HydrophobicContact CG2-CE3 4.17Å; T450-W458 HydrophobicContact CG2-CG 4.04Å; T450-W458 HydrophobicContact CG2-CH2 4.31Å; T450-W458 HydrophobicContact CG2-CZ2 3.81Å; T450-W458 HydrophobicContact CG2-CZ3 4.47Å; T454-W458 PolarHBondContact O-N 2.79Å; M455-W458 PolarHBondContact O-N 3.26Å; W458-K460 VanDerWaalsContact C-N 3.26Å; W458-K460 PolarHBondContact O-N 3.48Å; W458-V461 HydrophobicContact CE3-CB 4.32Å; W458-V461 HydrophobicContact CE3-CG1 4.4Å; W458-V461 HydrophobicContact CE3-CG2 4.4Å; W458-V461 HydrophobicContact CZ3-CG1 4.48Å; W458-V461 WeakPolarHBondContact O-CB 3.26Å; W458-V461 PolarHBondContact O-N 3.12Å; W458-V461 VanDerWaalsContact O-N 3.14Å; W458-F462 HydrophobicContact CB-CE2 4.31Å; W458-F462 HydrophobicContact CE3-CZ 4.23Å; W458-F462 VanDerWaalsContact O-CD2 3.27Å; W458-F462 WeakPolarHBondContact O-CD2 3.44Å; W458-F462 PolarHBondContact O-N 3.16Å
459	R	90.6	Very high	88.2	Confident	76 Å²	76	43.5 Å²	43.5	29%	0.287	22%	0.221	S	C	.	.	H	α-helix	trans	-56.6	-41	170.9	-76.6	179.9	177.7	150.4	8.5	111.6	E77 C385 M455 G457 W463	E77-R459 IonicContact OE2-CZ 3.85Å; E77-R459 VanDerWaalsContact OE2-CZ 3.23Å; E77-R459 IonicContact OE2-NH1 3.31Å; E77-R459 PolarHBondContact OE2-NH1 2.85Å; E77-R459 IonicContact OE2-NH2 2.88Å; E77-R459 PolarHBondContact OE2-NH2 2.7Å; C385-R459 HydrophobicContact CB-CG 3.9Å; C385-R459 PolarHBondContact O-NE 3.28Å; M455-R459 WeakPolarHBondContact O-CG 3.42Å; M455-R459 PolarHBondContact O-N 3.09Å; G457-R459 VanDerWaalsContact C-N 3.32Å; G457-R459 PolarHBondContact O-N 3.32Å; R459-W463 WeakPolarHBondContact O-CB 3.18Å; R459-W463 VanDerWaalsContact O-CD1 3.23Å; R459-W463 PolarHBondContact O-N 3.33Å
460	K	91.5	Very high	88.6	Confident	113 Å²	113	44 Å²	44	49%	0.491	23%	0.226	S	C	.	.	H	α-helix	trans	-63.5	-43.8	176.1	-62.4	171	-171.4	167.6	0	111.2	F449 A456 G457 W458 F462 W463 V464	F449-K460 HydrophobicContact CD1-CB 4.44Å; F449-K460 HydrophobicContact CD1-CD 4.08Å; F449-K460 HydrophobicContact CD2-CB 4.37Å; F449-K460 HydrophobicContact CE1-CD 4.49Å; F449-K460 HydrophobicContact CG-CB 4.23Å; A456-K460 PolarHBondContact O-N 3.11Å; G457-K460 WeakPolarHBondContact O-CB 3.13Å; G457-K460 PolarHBondContact O-N 3.41Å; W458-K460 VanDerWaalsContact C-N 3.26Å; W458-K460 PolarHBondContact O-N 3.48Å; K460-F462 PolarHBondContact O-N 2.81Å; K460-W463 PolarHBondContact O-N 3.44Å; K460-V464 WeakPolarHBondContact O-CB 3.4Å; K460-V464 VanDerWaalsContact O-CG2 3.31Å; K460-V464 WeakPolarHBondContact O-CG2 3.2Å; K460-V464 PolarHBondContact O-N 3.45Å
461	V	92.9	Very high	89.1	Confident	5 Å²	5	45.3 Å²	45.3	3%	0.03	24%	0.24	C	C	.	.	H	α-helix	trans	-57.2	-50.1	178.7	179.5	0	0	0	0	111	T309 T446 F449 T450 G457 W458 V464 A465	T309-V461 HydrophobicContact CG2-CG1 3.81Å; T446-V461 HydrophobicContact CG2-CG1 4.11Å; T446-V461 HydrophobicContact CG2-CG2 4.12Å; F449-V461 HydrophobicContact CB-CG2 3.75Å; F449-V461 HydrophobicContact CD2-CG2 4.13Å; F449-V461 HydrophobicContact CG-CG2 4.44Å; T450-V461 HydrophobicContact CG2-CG2 4.09Å; G457-V461 PolarHBondContact O-N 3.44Å; W458-V461 HydrophobicContact CE3-CB 4.32Å; W458-V461 HydrophobicContact CE3-CG1 4.4Å; W458-V461 HydrophobicContact CE3-CG2 4.4Å; W458-V461 HydrophobicContact CZ3-CG1 4.48Å; W458-V461 WeakPolarHBondContact O-CB 3.26Å; W458-V461 PolarHBondContact O-N 3.12Å; W458-V461 VanDerWaalsContact O-N 3.14Å; V461-V464 PolarHBondContact O-N 3.07Å; V461-A465 PolarHBondContact O-N 3.43Å
462	F	93.8	Very high	89.9	Confident	6 Å²	6	39.4 Å²	39.4	3%	0.026	21%	0.212	C	C	.	.	H	α-helix	trans	-68	-36.7	179.6	-63.6	-45.1	0	0	0	113.1	L310 Y317 L381 V384 L398 W458 K460 A465 A466	L310-F462 HydrophobicContact CD2-CE1 4.18Å; Y317-F462 HydrophobicContact CD1-CZ 4.36Å; Y317-F462 HydrophobicContact CD2-CE2 4.21Å; Y317-F462 HydrophobicContact CD2-CZ 4.07Å; Y317-F462 HydrophobicContact CE1-CE2 4.5Å; Y317-F462 HydrophobicContact CE1-CZ 4.3Å; Y317-F462 AromaticContact CE2-CE2 3.71Å; Y317-F462 HydrophobicContact CE2-CE2 3.71Å; Y317-F462 AromaticContact CE2-CZ 3.98Å; Y317-F462 HydrophobicContact CE2-CZ 3.98Å; Y317-F462 HydrophobicContact CG-CZ 4.24Å; Y317-F462 AromaticContact CZ-CE2 3.88Å; L381-F462 HydrophobicContact CB-CB 4.46Å; L381-F462 HydrophobicContact CD2-CD1 3.88Å; L381-F462 HydrophobicContact CD2-CE1 4.32Å; V384-F462 HydrophobicContact CG1-CD2 3.99Å; V384-F462 HydrophobicContact CG1-CE2 3.65Å; V384-F462 HydrophobicContact CG1-CZ 4.22Å; L398-F462 HydrophobicContact CD2-CE1 4.23Å; L398-F462 HydrophobicContact CD2-CZ 4.29Å; W458-F462 HydrophobicContact CB-CE2 4.31Å; W458-F462 HydrophobicContact CE3-CZ 4.23Å; W458-F462 VanDerWaalsContact O-CD2 3.27Å; W458-F462 WeakPolarHBondContact O-CD2 3.44Å; W458-F462 PolarHBondContact O-N 3.16Å; K460-F462 PolarHBondContact O-N 2.81Å; F462-A465 PolarHBondContact O-N 2.68Å; F462-A466 VanDerWaalsContact O-CB 3.29Å; F462-A466 WeakPolarHBondContact O-CB 3.3Å; F462-A466 PolarHBondContact O-N 3.38Å
463	W	94.3	Very high	90.9	Very high	122 Å²	122	34.6 Å²	34.6	46%	0.462	19%	0.187	S	C	.	.	H	α-helix	trans	-64.8	-40.6	174.1	-92.8	106.7	0	0	0	112.9	I382 R459 K460 A466 G467	I382-W463 HydrophobicContact CD1-CE3 4.23Å; I382-W463 HydrophobicContact CD1-CH2 3.98Å; I382-W463 HydrophobicContact CD1-CZ3 3.76Å; I382-W463 HydrophobicContact CG1-CD2 4.4Å; I382-W463 HydrophobicContact CG1-CE3 4.23Å; I382-W463 HydrophobicContact CG1-CH2 4.25Å; I382-W463 HydrophobicContact CG1-CZ2 4.41Å; I382-W463 HydrophobicContact CG1-CZ3 4.15Å; I382-W463 HydrophobicContact CG2-CH2 4.11Å; I382-W463 HydrophobicContact CG2-CZ2 3.86Å; R459-W463 WeakPolarHBondContact O-CB 3.18Å; R459-W463 VanDerWaalsContact O-CD1 3.23Å; R459-W463 PolarHBondContact O-N 3.33Å; K460-W463 PolarHBondContact O-N 3.44Å; W463-A466 PolarHBondContact O-N 3.13Å; W463-G467 PolarHBondContact O-N 2.97Å
464	V	95.2	Very high	92	Very high	52 Å²	52	34.4 Å²	34.4	32%	0.315	19%	0.191	S	C	.	.	H	α-helix	trans	-63.5	-47.4	175.3	168.6	0	0	0	0	110.4	W305 F449 K460 V461 A466 G467 I468	W305-V464 HydrophobicContact CZ2-CG1 4.13Å; F449-V464 HydrophobicContact CE2-CG2 4.03Å; K460-V464 WeakPolarHBondContact O-CB 3.4Å; K460-V464 VanDerWaalsContact O-CG2 3.31Å; K460-V464 WeakPolarHBondContact O-CG2 3.2Å; K460-V464 PolarHBondContact O-N 3.45Å; V461-V464 PolarHBondContact O-N 3.07Å; V464-A466 PolarHBondContact O-N 3.46Å; V464-G467 PolarHBondContact O-N 3.19Å; V464-I468 HydrophobicContact CG1-CD1 3.78Å; V464-I468 VanDerWaalsContact O-CG1 3.31Å; V464-I468 WeakPolarHBondContact O-CG1 3.37Å; V464-I468 PolarHBondContact O-N 2.73Å
465	A	94.6	Very high	92.7	Very high	2 Å²	2	36.4 Å²	36.4	2%	0.017	20%	0.2	C	C	.	.	H	α-helix	trans	-60.1	-43.7	176.4	0	0	0	0	0	112.3	L381 V461 F462 I468 N469	L381-A465 HydrophobicContact CD1-CB 3.94Å; V461-A465 PolarHBondContact O-N 3.43Å; F462-A465 PolarHBondContact O-N 2.68Å; A465-I468 PolarHBondContact O-N 3.2Å; A465-N469 PolarHBondContact O-N 3.24Å
466	A	95.2	Very high	93.4	Very high	0 Å²	0	36 Å²	36	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-63.5	-43.7	176.7	0	0	0	0	0	112.5	A378 I382 F462 W463 V464 N469 I470	A378-A466 HydrophobicContact CB-CB 3.92Å; I382-A466 HydrophobicContact CD1-CB 3.87Å; I382-A466 HydrophobicContact CG1-CB 3.67Å; F462-A466 VanDerWaalsContact O-CB 3.29Å; F462-A466 WeakPolarHBondContact O-CB 3.3Å; F462-A466 PolarHBondContact O-N 3.38Å; W463-A466 PolarHBondContact O-N 3.13Å; V464-A466 PolarHBondContact O-N 3.46Å; A466-N469 PolarHBondContact O-N 3.38Å; A466-I470 VanDerWaalsContact O-CG1 3.31Å; A466-I470 WeakPolarHBondContact O-CG1 3.49Å; A466-I470 PolarHBondContact O-N 2.91Å
467	G	96.1	Very high	93.9	Very high	43 Å²	43	38 Å²	38	44%	0.443	20%	0.202	S	C	.	.	H	α-helix	trans	-61.7	-43.4	176.7	0	0	0	0	0	112.6	W463 V464 I470 G471	W463-G467 PolarHBondContact O-N 2.97Å; V464-G467 PolarHBondContact O-N 3.19Å; G467-I470 PolarHBondContact O-N 3.39Å; G467-G471 PolarHBondContact O-N 2.87Å
468	I	96.1	Very high	94.3	Very high	49 Å²	49	43 Å²	43	25%	0.251	23%	0.227	S	C	.	.	H	α-helix	trans	-63	-44.3	176.6	-70.6	169.1	0	0	0	111	C302 W305 V464 A465 G471 G472	C302-I468 HydrophobicContact CB-CG2 3.86Å; C302-I468 WeakPolarHBondContact CB-O 3.28Å; C302-I468 PolarHBondContact SG-O 2.74Å; W305-I468 HydrophobicContact CB-CG2 4.03Å; W305-I468 HydrophobicContact CD2-CD1 3.52Å; W305-I468 VanDerWaalsContact CE2-CD1 3.44Å; W305-I468 HydrophobicContact CE3-CD1 4.02Å; W305-I468 HydrophobicContact CG-CD1 3.83Å; W305-I468 HydrophobicContact CG-CG2 4.14Å; W305-I468 HydrophobicContact CH2-CD1 4.34Å; W305-I468 HydrophobicContact CZ2-CD1 3.9Å; W305-I468 HydrophobicContact CZ3-CD1 4.4Å; V464-I468 HydrophobicContact CG1-CD1 3.78Å; V464-I468 VanDerWaalsContact O-CG1 3.31Å; V464-I468 WeakPolarHBondContact O-CG1 3.37Å; V464-I468 PolarHBondContact O-N 2.73Å; A465-I468 PolarHBondContact O-N 3.2Å; I468-G471 PolarHBondContact O-N 3.37Å; I468-G472 PolarHBondContact O-N 2.78Å
469	N	95.5	Very high	94.4	Very high	3 Å²	3	47.9 Å²	47.9	2%	0.016	25%	0.249	C	C	.	.	H	α-helix	trans	-63.3	-46.8	177.1	-80.2	1.8	0	0	0	112.4	C302 S306 L374 A378 A465 A466 G471 G472 A473	C302-N469 PolarHBondContact O-OD1 3.31Å; S306-N469 PolarHBondContact OG-ND2 3.47Å; S306-N469 PolarHBondContact OG-OD1 2.92Å; L374-N469 HydrophobicContact CB-CB 4.44Å; L374-N469 HydrophobicContact CD2-CB 4.06Å; L374-N469 WeakPolarHBondContact O-CB 3.12Å; A378-N469 HydrophobicContact CB-CB 3.99Å; A465-N469 PolarHBondContact O-N 3.24Å; A466-N469 PolarHBondContact O-N 3.38Å; N469-G471 VanDerWaalsContact C-N 3.35Å; N469-G472 PolarHBondContact O-N 2.66Å; N469-A473 WeakPolarHBondContact O-CB 3.22Å; N469-A473 PolarHBondContact O-N 3.1Å
470	I	96.5	Very high	94.3	Very high	64 Å²	64	44.5 Å²	44.5	33%	0.328	24%	0.238	S	C	.	.	H	α-helix	trans	-63.3	-43.7	179.2	-68.5	167.7	0	0	0	110.1	A378 A466 G467 G472 A473 V474	A378-I470 HydrophobicContact CB-CD1 4.05Å; A378-I470 HydrophobicContact CB-CG1 3.76Å; A466-I470 VanDerWaalsContact O-CG1 3.31Å; A466-I470 WeakPolarHBondContact O-CG1 3.49Å; A466-I470 PolarHBondContact O-N 2.91Å; G467-I470 PolarHBondContact O-N 3.39Å; I470-G472 PolarHBondContact O-N 3.38Å; I470-A473 WeakPolarHBondContact O-CB 3.31Å; I470-A473 PolarHBondContact O-N 3.05Å; I470-V474 WeakPolarHBondContact O-CG2 3.32Å; I470-V474 PolarHBondContact O-N 3Å
471	G	95.9	Very high	94.1	Very high	32 Å²	32	41.4 Å²	41.4	33%	0.33	23%	0.226	S	C	.	.	H	α-helix	trans	-58.1	-46.7	174.3	0	0	0	0	0	112.3	G467 I468 N469 A473 V474 I475	G467-G471 PolarHBondContact O-N 2.87Å; I468-G471 PolarHBondContact O-N 3.37Å; N469-G471 VanDerWaalsContact C-N 3.35Å; G471-A473 VanDerWaalsContact C-N 3.32Å; G471-A473 PolarHBondContact O-N 3.11Å; G471-V474 PolarHBondContact O-N 2.91Å; G471-I475 WeakPolarHBondContact O-CG1 3.43Å; G471-I475 PolarHBondContact O-N 2.76Å
472	G	95	Very high	93.6	Very high	0 Å²	0	41.5 Å²	41.5	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-60.7	-38	175.5	0	0	0	0	0	113.5	T299 C302 I468 N469 I470 Y476	T299-G472 PolarHBondContact OG1-O 3.08Å; T299-G472 VanDerWaalsContact OG1-O 3.09Å; C302-G472 VanDerWaalsContact SG-CA 3.53Å; I468-G472 PolarHBondContact O-N 2.78Å; N469-G472 PolarHBondContact O-N 2.66Å; I470-G472 PolarHBondContact O-N 3.38Å; G472-Y476 WeakPolarHBondContact O-CB 3.3Å; G472-Y476 PolarHBondContact O-N 3.13Å; G472-Y476 VanDerWaalsContact O-N 3.09Å
473	A	95.4	Very high	93.2	Very high	2 Å²	2	48.2 Å²	48.2	2%	0.017	26%	0.258	C	S	.	.	H	α-helix	trans	-66.7	-44.2	175.5	0	0	0	0	0	111.6	L374 V375 N469 I470 G471 Y476 M477	L374-A473 HydrophobicContact CB-CB 3.88Å; L374-A473 HydrophobicContact CD1-CB 4.16Å; V375-A473 HydrophobicContact CG2-CB 3.71Å; N469-A473 WeakPolarHBondContact O-CB 3.22Å; N469-A473 PolarHBondContact O-N 3.1Å; I470-A473 WeakPolarHBondContact O-CB 3.31Å; I470-A473 PolarHBondContact O-N 3.05Å; G471-A473 VanDerWaalsContact C-N 3.32Å; G471-A473 PolarHBondContact O-N 3.11Å; A473-Y476 PolarHBondContact O-N 3.04Å; A473-M477 WeakPolarHBondContact O-CB 3.44Å; A473-M477 VanDerWaalsContact O-CG 3.23Å; A473-M477 WeakPolarHBondContact O-CG 3.44Å; A473-M477 PolarHBondContact O-N 2.91Å
474	V	96	Very high	92.7	Very high	76 Å²	76	46.7 Å²	46.7	46%	0.461	26%	0.257	S	S	.	.	H	α-helix	trans	-61.2	-47	177.6	170.8	0	0	0	0	110.9	I470 G471 Y476 M477 I478	I470-V474 WeakPolarHBondContact O-CG2 3.32Å; I470-V474 PolarHBondContact O-N 3Å; G471-V474 PolarHBondContact O-N 2.91Å; V474-Y476 VanDerWaalsContact C-N 3.32Å; V474-Y476 PolarHBondContact O-N 2.9Å; V474-M477 PolarHBondContact O-N 3.33Å; V474-I478 HydrophobicContact CG1-CD1 3.81Å; V474-I478 WeakPolarHBondContact O-CG1 3.49Å; V474-I478 PolarHBondContact O-N 3.19Å; V474-I478 VanDerWaalsContact O-N 3.1Å
475	I	95.1	Very high	92.2	Very high	63 Å²	63	45.7 Å²	45.7	32%	0.323	25%	0.249	S	C	.	.	H	α-helix	trans	-57.7	-46.7	177.2	-68.4	168.5	0	0	0	110.5	T295 V298 G471 M477 I478 F479	T295-I475 HydrophobicContact CG2-CG2 4.17Å; V298-I475 HydrophobicContact CG1-CD1 3.88Å; G471-I475 WeakPolarHBondContact O-CG1 3.43Å; G471-I475 PolarHBondContact O-N 2.76Å; I475-M477 PolarHBondContact O-N 3.42Å; I475-I478 PolarHBondContact O-N 2.76Å; I475-F479 HydrophobicContact CG2-CD2 4.42Å; I475-F479 PolarHBondContact O-N 2.93Å
476	Y	94	Very high	91.5	Very high	2 Å²	2	48.2 Å²	48.2	1%	0.008	27%	0.271	C	S	.	.	H	α-helix	trans	-65.8	-37.2	179.2	-161.1	-96.8	0	0	0	113.2	T295 I296 T299 K367 T370 V412 N415 G472 A473 V474 I478 G480	T295-Y476 HydrophobicContact CG2-CD2 3.81Å; T295-Y476 HydrophobicContact CG2-CG 4.43Å; I296-Y476 HydrophobicContact CG1-CE2 4.41Å; T299-Y476 HydrophobicContact CG2-CD2 3.84Å; T299-Y476 HydrophobicContact CG2-CG 4.07Å; T299-Y476 WeakPolarHBondContact OG1-CB 3.35Å; K367-Y476 HydrophobicContact CG-CD1 4.21Å; K367-Y476 HydrophobicContact CG-CE1 4.12Å; T370-Y476 HydrophobicContact CG2-CD1 3.51Å; T370-Y476 HydrophobicContact CG2-CD2 4.18Å; T370-Y476 HydrophobicContact CG2-CE1 3.92Å; T370-Y476 HydrophobicContact CG2-CG 3.64Å; T370-Y476 WeakPolarHBondContact OG1-CE1 2.83Å; V412-Y476 HydrophobicContact CB-CE2 4.18Å; V412-Y476 HydrophobicContact CG2-CD2 4.34Å; V412-Y476 HydrophobicContact CG2-CE2 3.92Å; N415-Y476 WeakPolarHBondContact CB-OH 3.32Å; N415-Y476 VanDerWaalsContact CG-OH 3.22Å; N415-Y476 PolarHBondContact ND2-OH 3.43Å; G472-Y476 WeakPolarHBondContact O-CB 3.3Å; G472-Y476 PolarHBondContact O-N 3.13Å; G472-Y476 VanDerWaalsContact O-N 3.09Å; A473-Y476 PolarHBondContact O-N 3.04Å; V474-Y476 VanDerWaalsContact C-N 3.32Å; V474-Y476 PolarHBondContact O-N 2.9Å; Y476-I478 VanDerWaalsContact C-N 3.31Å; Y476-I478 PolarHBondContact O-N 2.88Å; Y476-G480 WeakPolarHBondContact O-CA 3.15Å; Y476-G480 PolarHBondContact O-N 3.35Å
477	M	93.8	Very high	90.7	Very high	81 Å²	81	49.4 Å²	49.4	40%	0.399	28%	0.275	S	S	.	.	H	α-helix	trans	-65.7	-36	178.1	-73.9	-59.3	-68.1	0	0	112	K367 F371 A473 V474 I475	K367-M477 HydrophobicContact CB-CE 4.45Å; K367-M477 HydrophobicContact CB-SD 3.74Å; K367-M477 HydrophobicContact CD-SD 4.27Å; K367-M477 WeakPolarHBondContact CE-O 3.42Å; K367-M477 HydrophobicContact CG-SD 4.08Å; K367-M477 PolarHBondContact NZ-O 2.68Å; F371-M477 HydrophobicContact CB-SD 4.15Å; F371-M477 HydrophobicContact CD2-CG 4.17Å; F371-M477 HydrophobicContact CD2-SD 4.4Å; A473-M477 WeakPolarHBondContact O-CB 3.44Å; A473-M477 VanDerWaalsContact O-CG 3.23Å; A473-M477 WeakPolarHBondContact O-CG 3.44Å; A473-M477 PolarHBondContact O-N 2.91Å; V474-M477 PolarHBondContact O-N 3.33Å; I475-M477 PolarHBondContact O-N 3.42Å
478	I	93.6	Very high	89.5	Confident	106 Å²	106	48 Å²	48	54%	0.544	26%	0.259	S	S	.	.	H	α-helix	trans	-77.8	-53.7	179.7	-61.7	167.7	0	0	0	110.9	V474 I475 Y476	V474-I478 HydrophobicContact CG1-CD1 3.81Å; V474-I478 WeakPolarHBondContact O-CG1 3.49Å; V474-I478 PolarHBondContact O-N 3.19Å; V474-I478 VanDerWaalsContact O-N 3.1Å; I475-I478 PolarHBondContact O-N 2.76Å; Y476-I478 VanDerWaalsContact C-N 3.31Å; Y476-I478 PolarHBondContact O-N 2.88Å
479	F	92.1	Very high	88.3	Confident	109 Å²	109	48.7 Å²	48.7	48%	0.478	26%	0.263	S	S	.	.	H	α-helix	trans	-106.7	-9.1	-167.4	-59.9	-72.2	0	0	0	114.8	V291 T295 I475 N481	V291-F479 HydrophobicContact CG1-CB 4.09Å; V291-F479 HydrophobicContact CG1-CD1 3.99Å; V291-F479 HydrophobicContact CG1-CG 4.23Å; T295-F479 HydrophobicContact CG2-CB 4.07Å; T295-F479 VanDerWaalsContact OG1-CB 3.22Å; T295-F479 WeakPolarHBondContact OG1-CB 3.38Å; I475-F479 HydrophobicContact CG2-CD2 4.42Å; I475-F479 PolarHBondContact O-N 2.93Å; F479-N481 PolarHBondContact O-N 3.08Å
480	G	87.6	Confident	86.5	Confident	5 Å²	5	56.2 Å²	56.2	5%	0.052	30%	0.298	C	S	.	.			trans	-63.7	129.5	179.6	0	0	0	0	0	112.1	K367 Y476	K367-G480 WeakPolarHBondContact CE-O 3.25Å; K367-G480 PolarHBondContact NZ-O 3.31Å; Y476-G480 WeakPolarHBondContact O-CA 3.15Å; Y476-G480 PolarHBondContact O-N 3.35Å
481	N	88.4	Confident	84.3	Confident	48 Å²	48	61.1 Å²	61.1	26%	0.257	32%	0.32	S	S	.	.			trans	-137.2	141.1	177.1	-164.1	3.1	0	0	0	109.5	P292 T363 N415 I419 F479 K483	P292-N481 HydrophobicContact CB-CB 4.31Å; P292-N481 HydrophobicContact CG-CB 4.16Å; T363-N481 PolarHBondContact OG1-OD1 3.27Å; N415-N481 PolarHBondContact ND2-O 3.3Å; N415-N481 PolarHBondContact OD1-O 3.38Å; I419-N481 WeakPolarHBondContact CG2-O 3.42Å; F479-N481 PolarHBondContact O-N 3.08Å; N481-K483 PolarHBondContact OD1-N 2.79Å
482	G	80.8	Confident	82.2	Confident	7 Å²	7	64.1 Å²	64.1	7%	0.072	33%	0.325	C	S	.	.			trans	-117.2	21.9	176.9	0	0	0	0	0	112.8	T363 N415	T363-G482 PolarHBondContact OG1-N 3.12Å; T363-G482 VanDerWaalsContact OG1-N 3.1Å; N415-G482 WeakPolarHBondContact OD1-CA 3.19Å
483	K	86.3	Confident	80.1	Confident	147 Å²	147	65.7 Å²	65.7	64%	0.639	33%	0.333	S	S	*	.	S	Bend	trans	-91.5	146.9	170.5	-68.1	-176.7	177.4	-174.3	0	110	N481 Q485	N481-K483 PolarHBondContact OD1-N 2.79Å; K483-Q485 PolarHBondContact O-N 3.34Å; K483-Q485 PolarHBondContact O-NE2 3.31Å
484	I	84.6	Confident	78	Confident	89 Å²	89	67.2 Å²	67.2	46%	0.456	35%	0.349	S	S	.	.	P	Polyproline II helix	trans	-56.6	133.5	172.9	-56.4	173.9	0	0	0	108.8	I419 A488 N489	I419-I484 WeakPolarHBondContact O-CA 3.49Å; I484-A488 HydrophobicContact CG2-CB 4.18Å; I484-N489 VanDerWaalsContact CG2-OD1 3.26Å; I484-N489 WeakPolarHBondContact CG2-OD1 3.12Å
485	Q	83.9	Confident	75.8	Confident	31 Å²	31	69.8 Å²	69.8	15%	0.145	36%	0.356	C	S	.	.	P	Polyproline II helix	trans	-84.9	149.9	179.8	-59.3	-60.3	-67.4	0	0	110.9	I419 K483 W487 A488	I419-Q485 HydrophobicContact CB-CG 4.07Å; I419-Q485 PolarHBondContact O-N 3.3Å; K483-Q485 PolarHBondContact O-N 3.34Å; K483-Q485 PolarHBondContact O-NE2 3.31Å; Q485-W487 VanDerWaalsContact C-N 3.31Å; Q485-W487 HydrophobicContact CB-CD2 4.22Å; Q485-W487 HydrophobicContact CB-CG 4.35Å; Q485-W487 HydrophobicContact CB-CZ2 4.05Å; Q485-W487 VanDerWaalsContact CB-NE1 3.33Å; Q485-W487 HydrophobicContact CG-CZ2 4.14Å; Q485-W487 PolarHBondContact O-N 3.04Å; Q485-A488 WeakPolarHBondContact O-CA 3.12Å; Q485-A488 WeakPolarHBondContact O-CB 3.27Å; Q485-A488 PolarHBondContact O-N 3.44Å
486	A	79.1	Confident	73.8	Confident	56 Å²	56	72.4 Å²	72.4	46%	0.463	37%	0.367	S	S	.	.	G	3₁₀ helix	trans	-52.2	-45.6	-176.9	0	0	0	0	0	112.9	A488 N489	A486-A488 PolarHBondContact O-N 3.5Å; A486-N489 PolarHBondContact O-N 2.05Å
487	W	78.2	Confident	71.9	Confident	25 Å²	25	76.3 Å²	76.3	10%	0.095	39%	0.386	C	S	.	.	G	3₁₀ helix	trans	-65.1	-5.9	177.9	57.1	-99.8	0	0	0	115.1	P283 M287 A420 Y423 L427 Q485	P283-W487 HydrophobicContact CG-CB 4.4Å; P283-W487 HydrophobicContact CG-CE3 4.4Å; M287-W487 HydrophobicContact CE-CE3 3.95Å; M287-W487 HydrophobicContact CE-CH2 3.92Å; M287-W487 HydrophobicContact CE-CZ3 3.28Å; M287-W487 HydrophobicContact CG-CD2 4.1Å; M287-W487 HydrophobicContact CG-CE3 3.76Å; M287-W487 HydrophobicContact CG-CH2 3.91Å; M287-W487 HydrophobicContact CG-CZ2 4.24Å; M287-W487 HydrophobicContact CG-CZ3 3.67Å; M287-W487 HydrophobicContact SD-CZ3 4.34Å; A420-W487 HydrophobicContact CB-CH2 3.31Å; A420-W487 HydrophobicContact CB-CZ2 4.25Å; A420-W487 HydrophobicContact CB-CZ3 3.49Å; A420-W487 VanDerWaalsContact CB-CZ3 3.49Å; Y423-W487 HydrophobicContact CD2-CE3 4.09Å; Y423-W487 AromaticContact CD2-CZ3 3.65Å; Y423-W487 HydrophobicContact CD2-CZ3 3.65Å; Y423-W487 HydrophobicContact CE2-CE3 4.23Å; Y423-W487 HydrophobicContact CE2-CZ3 4.26Å; Y423-W487 HydrophobicContact CG-CZ3 4.44Å; L427-W487 HydrophobicContact CD1-CH2 4.18Å; L427-W487 HydrophobicContact CD2-CH2 4.43Å; Q485-W487 VanDerWaalsContact C-N 3.31Å; Q485-W487 HydrophobicContact CB-CD2 4.22Å; Q485-W487 HydrophobicContact CB-CG 4.35Å; Q485-W487 HydrophobicContact CB-CZ2 4.05Å; Q485-W487 VanDerWaalsContact CB-NE1 3.33Å; Q485-W487 HydrophobicContact CG-CZ2 4.14Å; Q485-W487 PolarHBondContact O-N 3.04Å
488	A	72.1	Confident	69.9	Low	12 Å²	12	79.2 Å²	79.2	10%	0.099	40%	0.398	C	S	.	.	G	3₁₀ helix	trans	-110.5	-1.4	176.9	0	0	0	0	0	113.5	A420 Y423 I484 Q485 A486	A420-A488 HydrophobicContact CB-CB 3.73Å; Y423-A488 HydrophobicContact CD2-CB 4.45Å; I484-A488 HydrophobicContact CG2-CB 4.18Å; Q485-A488 WeakPolarHBondContact O-CA 3.12Å; Q485-A488 WeakPolarHBondContact O-CB 3.27Å; Q485-A488 PolarHBondContact O-N 3.44Å; A486-A488 PolarHBondContact O-N 3.5Å
489	N	70.3	Confident	67.9	Low	65 Å²	65	80.8 Å²	80.8	35%	0.348	40%	0.403	S	S	.	.			trans	-81.1	145.8	178	-83.6	-20.5	0	0	0	112.1	I484 A486	I484-N489 VanDerWaalsContact CG2-OD1 3.26Å; I484-N489 WeakPolarHBondContact CG2-OD1 3.12Å; A486-N489 PolarHBondContact O-N 2.05Å
490	E	57.7	Low	66.2	Low	160 Å²	160	83 Å²	83	75%	0.748	42%	0.415	S	S	*	.	H	α-helix	trans	-77.6	-31.7	-179.3	-68.4	-175.9	162.9	0	0	113.4	G494	E490-G494 PolarHBondContact O-N 2.87Å
491	E	51.4	Low	64.7	Low	168 Å²	168	92.1 Å²	92.1	79%	0.785	45%	0.448	S	S	*	.	H	α-helix	trans	-76.8	-44.5	-171.6	-66.4	176.3	169.7	0	0	112.5	G494 E495	E491-G494 PolarHBondContact O-N 3.41Å; E491-E495 PolarHBondContact O-N 3.38Å
492	E	50	Low	63.1	Low	94 Å²	94	93.8 Å²	93.8	44%	0.439	47%	0.469	S	S	.	.	H	α-helix	trans	-70.3	-40	-179.8	-83.6	175.2	151.8	0	0	112.9	G494 E495 E496	E492-G494 VanDerWaalsContact C-N 3.3Å; E492-G494 PolarHBondContact O-N 3.04Å; E492-E495 PolarHBondContact O-N 3.33Å; E492-E496 WeakPolarHBondContact O-CG 3.13Å; E492-E496 PolarHBondContact O-N 2.96Å
493	N	51.3	Low	62	Low	33 Å²	33	99.1 Å²	99.1	18%	0.176	50%	0.5	C	S	.	.	H	α-helix	trans	-69.8	-28.1	179	-87	29.1	0	0	0	112.7	E497	N493-E497 VanDerWaalsContact O-CB 3.3Å; N493-E497 WeakPolarHBondContact O-CB 3.34Å; N493-E497 WeakPolarHBondContact O-CG 3.29Å; N493-E497 PolarHBondContact O-N 3.42Å
494	G	51.6	Low	59.8	Low	34 Å²	34	94.2 Å²	94.2	35%	0.351	49%	0.491	S	S	.	.	H	α-helix	trans	-68.1	-41.8	174.1	0	0	0	0	0	111.7	E490 E491 E492 E498	E490-G494 PolarHBondContact O-N 2.87Å; E491-G494 PolarHBondContact O-N 3.41Å; E492-G494 VanDerWaalsContact C-N 3.3Å; E492-G494 PolarHBondContact O-N 3.04Å; G494-E498 WeakPolarHBondContact O-CB 3.33Å; G494-E498 WeakPolarHBondContact O-CG 3.28Å; G494-E498 PolarHBondContact O-N 2.66Å
495	E	50.2	Low	58.1	Low	130 Å²	130	96.5 Å²	96.5	61%	0.607	51%	0.511	S	S	*	.	H	α-helix	trans	-69.3	-42	175.8	-68.7	179.7	170.8	0	0	111.9	E491 E492 E498 E499	E491-E495 PolarHBondContact O-N 3.38Å; E492-E495 PolarHBondContact O-N 3.33Å; E495-E498 PolarHBondContact O-N 3.19Å; E495-E499 WeakPolarHBondContact O-CB 2.99Å; E495-E499 PolarHBondContact O-N 2.88Å
496	E	52	Low	56.1	Low	118 Å²	118	104.2 Å²	104.2	55%	0.551	57%	0.569	S	S	*	*	H	α-helix	trans	-66	-41	175.6	-75.9	-175.9	169.9	0	0	112.6	E492 E498 E499 E500	E492-E496 WeakPolarHBondContact O-CG 3.13Å; E492-E496 PolarHBondContact O-N 2.96Å; E496-E498 VanDerWaalsContact C-N 3.33Å; E496-E499 PolarHBondContact O-N 3.49Å; E496-E500 WeakPolarHBondContact O-CB 3.37Å; E496-E500 WeakPolarHBondContact O-CG 3.38Å; E496-E500 PolarHBondContact O-N 2.78Å
497	E	54	Low	54.9	Low	85 Å²	85	106.7 Å²	106.7	40%	0.397	57%	0.574	S	S	.	*	H	α-helix	trans	-69.1	-30.8	175.4	-77.4	-174.1	-169.9	0	0	112.3	N493 R501	N493-E497 VanDerWaalsContact O-CB 3.3Å; N493-E497 WeakPolarHBondContact O-CB 3.34Å; N493-E497 WeakPolarHBondContact O-CG 3.29Å; N493-E497 PolarHBondContact O-N 3.42Å; E497-R501 WeakPolarHBondContact O-CB 3.27Å; E497-R501 VanDerWaalsContact O-CG 3.3Å; E497-R501 WeakPolarHBondContact O-CG 3.41Å; E497-R501 PolarHBondContact O-N 3.35Å; E497-R501 VanDerWaalsContact O-N 3.13Å
498	E	52.3	Low	53.7	Low	142 Å²	142	110.9 Å²	110.9	66%	0.664	60%	0.599	S	S	*	*	H	α-helix	trans	-72.7	-39.3	171.8	-80.2	-173.1	169	0	0	112.1	G494 E495 E496 R501 A502	G494-E498 WeakPolarHBondContact O-CB 3.33Å; G494-E498 WeakPolarHBondContact O-CG 3.28Å; G494-E498 PolarHBondContact O-N 2.66Å; E495-E498 PolarHBondContact O-N 3.19Å; E496-E498 VanDerWaalsContact C-N 3.33Å; E498-R501 PolarHBondContact O-N 3.34Å; E498-A502 VanDerWaalsContact O-CB 3.31Å; E498-A502 WeakPolarHBondContact O-CB 2.96Å; E498-A502 PolarHBondContact O-N 3.47Å
499	E	52.8	Low	52.7	Low	138 Å²	138	116.4 Å²	116.4	65%	0.645	63%	0.627	S	S	*	*	H	α-helix	trans	-66.8	-44.3	173.4	-80.6	-169.1	154	0	0	112.1	E495 E496 R501 A502 V503	E495-E499 WeakPolarHBondContact O-CB 2.99Å; E495-E499 PolarHBondContact O-N 2.88Å; E496-E499 PolarHBondContact O-N 3.49Å; E499-R501 VanDerWaalsContact C-N 3.3Å; E499-R501 PolarHBondContact O-N 3.26Å; E499-A502 WeakPolarHBondContact O-CB 3.4Å; E499-A502 PolarHBondContact O-N 2.81Å; E499-A502 VanDerWaalsContact O-N 3.08Å; E499-V503 VanDerWaalsContact O-CG2 3.28Å; E499-V503 WeakPolarHBondContact O-CG2 3.43Å; E499-V503 PolarHBondContact O-N 2.9Å
500	E	55.5	Low	51.6	Low	157 Å²	157	119.5 Å²	119.5	73%	0.734	64%	0.644	S	S	*	*	H	α-helix	trans	-64.4	-33.8	175.6	-79	-169	158.3	0	0	112.3	E496	E496-E500 WeakPolarHBondContact O-CB 3.37Å; E496-E500 WeakPolarHBondContact O-CG 3.38Å; E496-E500 PolarHBondContact O-N 2.78Å
501	R	55.5	Low	51.2	Low	195 Å²	195	116.9 Å²	116.9	74%	0.736	64%	0.637	S	S	*	*	H	α-helix	trans	-71.6	-32.6	170.7	-79.2	-178.3	-164.9	165.8	14.2	112.8	E497 E498 E499 V503	E497-R501 WeakPolarHBondContact O-CB 3.27Å; E497-R501 VanDerWaalsContact O-CG 3.3Å; E497-R501 WeakPolarHBondContact O-CG 3.41Å; E497-R501 PolarHBondContact O-N 3.35Å; E497-R501 VanDerWaalsContact O-N 3.13Å; E498-R501 PolarHBondContact O-N 3.34Å; E499-R501 VanDerWaalsContact C-N 3.3Å; E499-R501 PolarHBondContact O-N 3.26Å; R501-V503 VanDerWaalsContact C-N 3.29Å
502	A	56.1	Low	51.2	Low	84 Å²	84	113.5 Å²	113.5	69%	0.694	63%	0.627	S	S	*	*	H	α-helix	trans	-71.3	-24.9	176.1	0	0	0	0	0	112.5	E498 E499 G504	E498-A502 VanDerWaalsContact O-CB 3.31Å; E498-A502 WeakPolarHBondContact O-CB 2.96Å; E498-A502 PolarHBondContact O-N 3.47Å; E499-A502 WeakPolarHBondContact O-CB 3.4Å; E499-A502 PolarHBondContact O-N 2.81Å; E499-A502 VanDerWaalsContact O-N 3.08Å; A502-G504 VanDerWaalsContact C-N 3.33Å; A502-G504 PolarHBondContact O-N 3.21Å
503	V	58.2	Low	51.3	Low	119 Å²	119	114.9 Å²	114.9	72%	0.721	64%	0.641	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96	27.7	179.2	-174.6	0	0	0	0	112.2	E499 R501	E499-V503 VanDerWaalsContact O-CG2 3.28Å; E499-V503 WeakPolarHBondContact O-CG2 3.43Å; E499-V503 PolarHBondContact O-N 2.9Å; R501-V503 VanDerWaalsContact C-N 3.29Å
504	G	39.2	Very low	51.3	Low	44 Å²	44	121.2 Å²	121.2	45%	0.454	68%	0.676	S	S	.	*			trans	-48	151.6	175.5	0	0	0	0	0	114.1	A502 S506	A502-G504 VanDerWaalsContact C-N 3.33Å; A502-G504 PolarHBondContact O-N 3.21Å; G504-S506 PolarHBondContact O-N 2.95Å
505	P	49.3	Very low	51.3	Low	137 Å²	137	128.5 Å²	128.5	89%	0.89	70%	0.704	S	S	*	*			trans	-62.7	126.5	-157.7	26.6	-33.9	0	0	0	111.8
506	S	40.5	Very low	51.4	Low	193 Å²	193	128.4 Å²	128.4	100%	1.35	71%	0.712	S	S	*	*			trans	-82.8	0	167.2	17.7	0	0	0	0	111.7	G504	G504-S506 PolarHBondContact O-N 2.95Å

Retrieved 506 of 506 residues in 618.7 ms (Link to these results)

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