A0A087XME2_POEFO Loading...

E3 ubiquitin-protein ligase HACE1

AlphaFold DB (A0A3B3UCH6), UniProt , Accession A0A087XME2, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 897 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M46.8Very low47.3Very low227 Ų227139.8 Ų139.8100%1.11869%0.688SS**  0-23.10-135.9-175.6-75.700112.8
2M41.9Very low47.1Very low163 Ų163138.6 Ų138.680%0.80368%0.68SS**  trans-81.7-25.8178.2-139.1175.1-94.400114.2A5 M6M2-A5 PolarHBondContact O-N 3.49Å; M2-M6 PolarHBondContact O-N 3.46Å
3E45.8Very low46.9Very low171 Ų171135.2 Ų135.280%0.79967%0.665SS**Hα-helixtrans-71.1-34.8176.3-85.6175142.200114A5 M6 E7E3-A5 VanDerWaalsContact C-N 3.27Å; E3-A5 PolarHBondContact O-N 3.01Å; E3-M6 PolarHBondContact O-N 3.36Å; E3-E7 PolarHBondContact O-N 3.19Å
4R47.6Very low46.7Very low208 Ų208130.3 Ų130.379%0.78565%0.651SS**Hα-helixtrans-69.5-22175.8-90.4-175.8175.2176.5-1.2113.6Q8R4-Q8 PolarHBondContact O-N 3.19Å
5A43.4Very low46.6Very low56 Ų56134.1 Ų134.146%0.46366%0.655SS.*Hα-helixtrans-80.5-34.8176.900000112M2 E3 L9M2-A5 PolarHBondContact O-N 3.49Å; E3-A5 VanDerWaalsContact C-N 3.27Å; E3-A5 PolarHBondContact O-N 3.01Å; A5-L9 PolarHBondContact O-N 3.42Å
6M43.5Very low46.2Very low141 Ų141132.9 Ų132.970%0.69565%0.652SS**Hα-helixtrans-74.2-31.9175.2-90.3166.315800113M2 E3 L9 N10M2-M6 PolarHBondContact O-N 3.46Å; E3-M6 PolarHBondContact O-N 3.36Å; M6-L9 PolarHBondContact O-N 3.3Å; M6-N10 PolarHBondContact O-N 3.47Å
7E52.1Low45.9Very low138 Ų138129.4 Ų129.465%0.64564%0.64SS**Hα-helixtrans-65.9-37.9172.1-114.1175.316900112.4E3 V11E3-E7 PolarHBondContact O-N 3.19Å; E7-V11 WeakPolarHBondContact O-CB 3.34Å; E7-V11 VanDerWaalsContact O-CG2 3.24Å; E7-V11 WeakPolarHBondContact O-CG2 3.41Å; E7-V11 PolarHBondContact O-N 3.4Å
8Q48.3Very low45.6Very low143 Ų143132.5 Ų132.567%0.66864%0.643SS**Hα-helixtrans-69.8-35.3175-79.6-174.4-17.600113R4 V11 Q12R4-Q8 PolarHBondContact O-N 3.19Å; Q8-V11 PolarHBondContact O-N 3.44Å; Q8-Q12 PolarHBondContact O-N 2.83Å
9L47Very low45.2Very low103 Ų103130.2 Ų130.254%0.53964%0.642SS.*Hα-helixtrans-69.2-38.7176.1-137.194.1000111.7A5 M6 Q12 L13A5-L9 PolarHBondContact O-N 3.42Å; M6-L9 PolarHBondContact O-N 3.3Å; L9-Q12 PolarHBondContact O-N 3.39Å; L9-L13 HydrophobicContact CD2-CD1 4.3Å; L9-L13 WeakPolarHBondContact O-CB 3.24Å; L9-L13 PolarHBondContact O-N 2.96Å
10N48.5Very low45Very low114 Ų114130.8 Ų130.861%0.6165%0.647SS**Hα-helixtrans-71.7-29.9175.1-92.7-16.6000113M6 S14M6-N10 PolarHBondContact O-N 3.47Å; N10-S14 WeakPolarHBondContact O-CB 3.49Å; N10-S14 PolarHBondContact O-N 3.08Å; N10-S14 PolarHBondContact O-OG 3.23Å
11V55.5Low44.6Very low74 Ų74134.7 Ų134.745%0.44866%0.655SS.*Hα-helixtrans-71.8-32.9170.3172.30000111.6E7 Q8 S14 R15E7-V11 WeakPolarHBondContact O-CB 3.34Å; E7-V11 VanDerWaalsContact O-CG2 3.24Å; E7-V11 WeakPolarHBondContact O-CG2 3.41Å; E7-V11 PolarHBondContact O-N 3.4Å; Q8-V11 PolarHBondContact O-N 3.44Å; V11-S14 WeakPolarHBondContact CA-OG 3.28Å; V11-S14 PolarHBondContact O-OG 2.71Å; V11-R15 WeakPolarHBondContact O-CB 3.4Å; V11-R15 VanDerWaalsContact O-CG 3.28Å; V11-R15 WeakPolarHBondContact O-CG 3.36Å; V11-R15 PolarHBondContact O-N 2.93Å; V11-R15 VanDerWaalsContact O-N 3.08Å
12Q45.4Very low44.1Very low125 Ų125133 Ų13358%0.58464%0.636SS**Hα-helixtrans-73.7-43.1173.1-83.9-176.4-28.600112.9Q8 L9 R15 L16Q8-Q12 PolarHBondContact O-N 2.83Å; L9-Q12 PolarHBondContact O-N 3.39Å; Q12-R15 PolarHBondContact O-N 3.46Å; Q12-L16 PolarHBondContact O-N 3.28Å
13L44Very low44.1Very low94 Ų94130 Ų13049%0.49264%0.636SS.*Hα-helixtrans-64.8-43.8175.2-94.9146.7000111.3L9 R15 L16 T17L9-L13 HydrophobicContact CD2-CD1 4.3Å; L9-L13 WeakPolarHBondContact O-CB 3.24Å; L9-L13 PolarHBondContact O-N 2.96Å; L13-R15 VanDerWaalsContact C-N 3.31Å; L13-R15 PolarHBondContact O-N 2.89Å; L13-L16 PolarHBondContact O-N 2.83Å; L13-L16 VanDerWaalsContact O-N 3.14Å; L13-T17 PolarHBondContact O-N 3.14Å; L13-T17 PolarHBondContact O-OG1 3.02Å
14S43.7Very low44Very low67 Ų67132.3 Ų132.347%0.46964%0.638SS.*Hα-helixtrans-67.1-28.1174.860.50000113.5N10 V11 R18N10-S14 WeakPolarHBondContact O-CB 3.49Å; N10-S14 PolarHBondContact O-N 3.08Å; N10-S14 PolarHBondContact O-OG 3.23Å; V11-S14 WeakPolarHBondContact CA-OG 3.28Å; V11-S14 PolarHBondContact O-OG 2.71Å; S14-R18 WeakPolarHBondContact O-CB 3.22Å; S14-R18 PolarHBondContact O-N 3.03Å
15R45.3Very low44Very low187 Ų187127.9 Ų127.971%0.70663%0.634SS**Hα-helixtrans-69.9-39.4168.5-83.2178.4175.6-176.8-0.6112.4V11 Q12 L13 R18 S19V11-R15 WeakPolarHBondContact O-CB 3.4Å; V11-R15 VanDerWaalsContact O-CG 3.28Å; V11-R15 WeakPolarHBondContact O-CG 3.36Å; V11-R15 PolarHBondContact O-N 2.93Å; V11-R15 VanDerWaalsContact O-N 3.08Å; Q12-R15 PolarHBondContact O-N 3.46Å; L13-R15 VanDerWaalsContact C-N 3.31Å; L13-R15 PolarHBondContact O-N 2.89Å; R15-R18 PolarHBondContact O-N 3.24Å; R15-S19 WeakPolarHBondContact O-CB 3.05Å; R15-S19 PolarHBondContact O-N 2.91Å
16L39.8Very low44.5Very low115 Ų115129 Ų12960%0.60264%0.635SS**Hα-helixtrans-69.5-42.6177.4-123.4122.4000111.8Q12 L13 R18 S19 L20Q12-L16 PolarHBondContact O-N 3.28Å; L13-L16 PolarHBondContact O-N 2.83Å; L13-L16 VanDerWaalsContact O-N 3.14Å; L16-R18 VanDerWaalsContact C-N 3.33Å; L16-R18 PolarHBondContact O-N 3.05Å; L16-S19 WeakPolarHBondContact O-CB 3.5Å; L16-S19 PolarHBondContact O-N 3.48Å; L16-L20 HydrophobicContact CD2-CD1 4.47Å; L16-L20 PolarHBondContact O-N 3.47Å
17T41.5Very low45.4Very low73 Ų73130 Ų13045%0.44864%0.638SS.*Hα-helixtrans-70.9-27.7175.9-37.30000112.3L13 R21L13-T17 PolarHBondContact O-N 3.14Å; L13-T17 PolarHBondContact O-OG1 3.02Å; T17-R21 PolarHBondContact O-N 2.81Å
18R39.9Very low46.4Very low186 Ų186124.3 Ų124.370%0.70261%0.612SS**Hα-helixtrans-78.9-25.9171.9-167.9177.4-102.3174.6-5.8112.5S14 R15 L16S14-R18 WeakPolarHBondContact O-CB 3.22Å; S14-R18 PolarHBondContact O-N 3.03Å; R15-R18 PolarHBondContact O-N 3.24Å; L16-R18 VanDerWaalsContact C-N 3.33Å; L16-R18 PolarHBondContact O-N 3.05Å
19S38.1Very low47.6Very low89 Ų89119.7 Ų119.762%0.62259%0.594SS**Hα-helixtrans-74.6-27.7171.1-170.60000113R15 L16R15-S19 WeakPolarHBondContact O-CB 3.05Å; R15-S19 PolarHBondContact O-N 2.91Å; L16-S19 WeakPolarHBondContact O-CB 3.5Å; L16-S19 PolarHBondContact O-N 3.48Å
20L41.8Very low49Very low142 Ų142124 Ų12474%0.74361%0.611SS**SBendtrans-88.9-3.7177.7-76.2162000114.1L16L16-L20 HydrophobicContact CD2-CD1 4.47Å; L16-L20 PolarHBondContact O-N 3.47Å
21R36.6Very low50.7Low213 Ų213122.1 Ų122.180%0.80460%0.602SS**SBendtrans-117.53.6179.3-81.1-169.7-171.6-174.84.1115.3T17T17-R21 PolarHBondContact O-N 2.81Å
22R36.7Very low52.1Low192 Ų192120.5 Ų120.573%0.72559%0.59SS**SBendtrans-116.3109.7168.4-77-175.1173.5-175.9-3.6107.7R24R22-R24 VanDerWaalsContact C-N 3.3Å; R22-R24 PolarHBondContact O-N 2.86Å
23A42.6Very low53.9Low99 Ų99119.5 Ų119.582%0.81859%0.586SS**  trans-41.8101.9157.100000107.6T25A23-T25 VanDerWaalsContact C-N 3.34Å; A23-T25 PolarHBondContact O-N 2.83Å
24R42.6Very low55.7Low219 Ų219118.6 Ų118.683%0.82658%0.584SS**  trans-64.4113.6148.4-87.2-177.1172.4179.1-3.3102.7R22 V26R22-R24 VanDerWaalsContact C-N 3.3Å; R22-R24 PolarHBondContact O-N 2.86Å; R24-V26 PolarHBondContact O-N 2.77Å
25T47.6Very low57.7Low116 Ų116115.4 Ų115.471%0.71256%0.562SS**  trans-47.595148.641.20000104.8A23 E27A23-T25 VanDerWaalsContact C-N 3.34Å; A23-T25 PolarHBondContact O-N 2.83Å; T25-E27 PolarHBondContact O-N 3.21Å
26V55Low59.6Low78 Ų78106.5 Ų106.547%0.47353%0.528SS..  trans-66.495.6169.8173.30000101.8R24 L28 T38 L54R24-V26 PolarHBondContact O-N 2.77Å; V26-L28 PolarHBondContact O-N 3.33Å; V26-T38 HydrophobicContact CG1-CG2 4.48Å; V26-L54 HydrophobicContact CB-CD2 4.11Å; V26-L54 HydrophobicContact CG1-CD2 4.48Å; V26-L54 WeakPolarHBondContact O-CD2 3.47Å
27E61.3Low61.6Low164 Ų164106.9 Ų106.977%0.76652%0.522SS*.PPolyproline II helixtrans-63.3126.1171.1-73.3177.618000105.7T25T25-E27 PolarHBondContact O-N 3.21Å
28L72.8Confident63.6Low18 Ų18105.4 Ų105.49%0.09451%0.514CS..PPolyproline II helixtrans-60.5129.7176.8-149.985000107V26 E30 A35 L39 L54 F60V26-L28 PolarHBondContact O-N 3.33Å; L28-E30 PolarHBondContact O-N 3.48Å; L28-A35 HydrophobicContact CD2-CB 3.61Å; L28-A35 HydrophobicContact CG-CB 3.85Å; L28-L39 HydrophobicContact CD1-CD1 4.1Å; L28-L39 HydrophobicContact CD1-CD2 3.62Å; L28-L39 HydrophobicContact CD1-CG 3.7Å; L28-L39 HydrophobicContact CD2-CD1 3.88Å; L28-L39 HydrophobicContact CD2-CG 4.38Å; L28-L54 HydrophobicContact CD1-CB 3.86Å; L28-L54 HydrophobicContact CD1-CD1 4.15Å; L28-L54 HydrophobicContact CD1-CD2 4.49Å; L28-L54 HydrophobicContact CD1-CG 4.4Å; L28-F60 HydrophobicContact CD2-CB 3.72Å; L28-F60 HydrophobicContact CD2-CD2 4.31Å; L28-F60 HydrophobicContact CD2-CG 4.07Å
29P75Confident65.8Low45 Ų4596.6 Ų96.629%0.29248%0.48SS..PPolyproline II helixtrans-48.9141.8175.3-27.733.8000111.5D31 T34P29-D31 PolarHBondContact O-N 3.47Å; P29-T34 HydrophobicContact CB-CG2 4.08Å; P29-T34 HydrophobicContact CG-CG2 3.9Å
30E75.7Confident67.9Low193 Ų19394.2 Ų94.290%0.90246%0.46SS*.SBendtrans-65.8-27.2179.5-65.4-166.7154.700112.5L28L28-E30 PolarHBondContact O-N 3.48Å
31D83.7Confident69.7Low76 Ų7691.1 Ų91.141%0.40645%0.448SS..SBendtrans-77.4124.6175.2167.658000111.4P29 E33 T34 A35P29-D31 PolarHBondContact O-N 3.47Å; D31-E33 VanDerWaalsContact C-N 3.27Å; D31-E33 PolarHBondContact O-N 3.4Å; D31-E33 PolarHBondContact OD1-N 2.95Å; D31-E33 WeakPolarHBondContact OD2-CB 2.81Å; D31-E33 PolarHBondContact OD2-N 3.44Å; D31-T34 PolarHBondContact O-N 3.23Å; D31-T34 WeakPolarHBondContact OD2-CB 3.49Å; D31-T34 PolarHBondContact OD2-N 2.98Å; D31-T34 PolarHBondContact OD2-OG1 3.42Å; D31-A35 WeakPolarHBondContact O-CB 3.45Å; D31-A35 PolarHBondContact O-N 3.4Å
32N85.2Confident72Confident40 Ų4083 Ų8321%0.21442%0.42CS..Hα-helixtrans-61.4-33.7-179-76.9-35.5000112.6V36 F60 D61 Y64N32-V36 WeakPolarHBondContact O-CB 3.42Å; N32-V36 PolarHBondContact O-N 3.32Å; N32-V36 VanDerWaalsContact O-N 3.08Å; N32-F60 HydrophobicContact CB-CD2 4.29Å; N32-F60 HydrophobicContact CB-CE2 4.22Å; N32-F60 WeakPolarHBondContact OD1-CA 3.22Å; N32-F60 WeakPolarHBondContact OD1-CD2 3.49Å; N32-D61 PolarHBondContact OD1-N 3.38Å; N32-Y64 HydrophobicContact CB-CD1 3.96Å; N32-Y64 HydrophobicContact CB-CD2 3.47Å; N32-Y64 VanDerWaalsContact CB-CD2 3.47Å; N32-Y64 HydrophobicContact CB-CE1 4.12Å; N32-Y64 HydrophobicContact CB-CE2 3.65Å; N32-Y64 HydrophobicContact CB-CG 3.64Å
33E83.6Confident74.4Confident104 Ų10473.9 Ų73.949%0.48639%0.385SS..Hα-helixtrans-63.8-50.6179.7-166.8172.1-177.800110.9D31 V36 Y37 Y64D31-E33 VanDerWaalsContact C-N 3.27Å; D31-E33 PolarHBondContact O-N 3.4Å; D31-E33 PolarHBondContact OD1-N 2.95Å; D31-E33 WeakPolarHBondContact OD2-CB 2.81Å; D31-E33 PolarHBondContact OD2-N 3.44Å; E33-V36 WeakPolarHBondContact O-CG1 3.19Å; E33-V36 PolarHBondContact O-N 2.85Å; E33-Y37 HydrophobicContact CG-CE2 4.18Å; E33-Y37 WeakPolarHBondContact O-CD2 3.22Å; E33-Y64 WeakPolarHBondContact CA-OH 3.39Å; E33-Y64 HydrophobicContact CB-CE1 4.37Å; E33-Y64 VanDerWaalsContact CB-OH 3.31Å; E33-Y64 WeakPolarHBondContact CB-OH 3.32Å
34T81.4Confident76.3Confident74 Ų7474 Ų7445%0.45437%0.37SS..Hα-helixtrans-70.6-37.8-179.5-48.30000112P29 D31 V36 Y37 T38P29-T34 HydrophobicContact CB-CG2 4.08Å; P29-T34 HydrophobicContact CG-CG2 3.9Å; D31-T34 PolarHBondContact O-N 3.23Å; D31-T34 WeakPolarHBondContact OD2-CB 3.49Å; D31-T34 PolarHBondContact OD2-N 2.98Å; D31-T34 PolarHBondContact OD2-OG1 3.42Å; T34-V36 VanDerWaalsContact C-N 3.32Å; T34-V36 PolarHBondContact O-N 3.06Å; T34-Y37 PolarHBondContact O-N 3.49Å; T34-T38 PolarHBondContact O-N 3.4Å; T34-T38 PolarHBondContact O-OG1 3.01Å
35A85Confident78.2Confident0 Ų066.4 Ų66.40%035%0.354CS..Hα-helixtrans-59.2-41.1176.100000112.4L28 D31 Y37 T38 L39 F60L28-A35 HydrophobicContact CD2-CB 3.61Å; L28-A35 HydrophobicContact CG-CB 3.85Å; D31-A35 WeakPolarHBondContact O-CB 3.45Å; D31-A35 PolarHBondContact O-N 3.4Å; A35-Y37 PolarHBondContact O-N 2.73Å; A35-T38 WeakPolarHBondContact O-CB 3.39Å; A35-T38 PolarHBondContact O-N 3.32Å; A35-T38 VanDerWaalsContact O-N 3.14Å; A35-L39 PolarHBondContact O-N 3.06Å; A35-F60 HydrophobicContact CB-CD2 3.63Å; A35-F60 HydrophobicContact CB-CE2 4.05Å
36V86.6Confident80.1Confident0 Ų063.2 Ų63.20%033%0.333CS..Hα-helixtrans-68.7-35.1-176.196.80000112.8N32 E33 T34 T38 L39 M40 F60 Y64 F66 L73N32-V36 WeakPolarHBondContact O-CB 3.42Å; N32-V36 PolarHBondContact O-N 3.32Å; N32-V36 VanDerWaalsContact O-N 3.08Å; E33-V36 WeakPolarHBondContact O-CG1 3.19Å; E33-V36 PolarHBondContact O-N 2.85Å; T34-V36 VanDerWaalsContact C-N 3.32Å; T34-V36 PolarHBondContact O-N 3.06Å; V36-T38 PolarHBondContact O-N 2.84Å; V36-L39 PolarHBondContact O-N 2.95Å; V36-M40 VanDerWaalsContact O-CB 3.28Å; V36-M40 WeakPolarHBondContact O-CB 3.24Å; V36-M40 PolarHBondContact O-N 3.47Å; V36-F60 HydrophobicContact CB-CE2 4.06Å; V36-F60 HydrophobicContact CB-CZ 4.17Å; V36-F60 HydrophobicContact CG2-CE2 4.08Å; V36-F60 HydrophobicContact CG2-CZ 3.66Å; V36-Y64 HydrophobicContact CB-CD1 4.24Å; V36-Y64 HydrophobicContact CG1-CD1 4.45Å; V36-Y64 HydrophobicContact CG1-CE1 4.37Å; V36-Y64 HydrophobicContact CG2-CD1 4.39Å; V36-F66 HydrophobicContact CB-CD1 4Å; V36-F66 HydrophobicContact CB-CE1 4.38Å; V36-F66 HydrophobicContact CB-CG 4.31Å; V36-F66 HydrophobicContact CG1-CB 3.72Å; V36-F66 HydrophobicContact CG1-CD1 3.54Å; V36-F66 HydrophobicContact CG1-CD2 3.8Å; V36-F66 HydrophobicContact CG1-CE1 4.09Å; V36-F66 HydrophobicContact CG1-CE2 4.39Å; V36-F66 HydrophobicContact CG1-CG 3.36Å; V36-F66 HydrophobicContact CG2-CD1 3.29Å; V36-F66 HydrophobicContact CG2-CE1 3.36Å; V36-F66 HydrophobicContact CG2-CG 4.06Å; V36-F66 HydrophobicContact CG2-CZ 4.23Å; V36-L73 HydrophobicContact CG2-CD1 4.02Å; V36-L73 HydrophobicContact CG2-CD2 3.73Å; V36-L73 HydrophobicContact CG2-CG 3.63Å
37Y81.5Confident81.7Confident123 Ų12363.8 Ų63.848%0.48233%0.331SS..Hα-helixtrans-69.7-23.5174.9-71.9-68.2000112.6E33 T34 A35 P41E33-Y37 HydrophobicContact CG-CE2 4.18Å; E33-Y37 WeakPolarHBondContact O-CD2 3.22Å; T34-Y37 PolarHBondContact O-N 3.49Å; A35-Y37 PolarHBondContact O-N 2.73Å; Y37-P41 WeakPolarHBondContact O-CD 3.33Å
38T82.7Confident82.9Confident43 Ų4359.2 Ų59.226%0.26431%0.309SS..Hα-helixtrans-77.3-40.9172.2-53.40000111.3V26 T34 A35 V36 M42V26-T38 HydrophobicContact CG1-CG2 4.48Å; T34-T38 PolarHBondContact O-N 3.4Å; T34-T38 PolarHBondContact O-OG1 3.01Å; A35-T38 WeakPolarHBondContact O-CB 3.39Å; A35-T38 PolarHBondContact O-N 3.32Å; A35-T38 VanDerWaalsContact O-N 3.14Å; V36-T38 PolarHBondContact O-N 2.84Å; T38-M42 HydrophobicContact CG2-CE 4.41Å
39L85.6Confident83.5Confident0 Ų067.5 Ų67.50%034%0.339CS..Hα-helixtrans-77.5-34.5-178.8-70.4176.8000113.5L28 A35 V36 M42 V43 V51 L54 L55 F60 L73L28-L39 HydrophobicContact CD1-CD1 4.1Å; L28-L39 HydrophobicContact CD1-CD2 3.62Å; L28-L39 HydrophobicContact CD1-CG 3.7Å; L28-L39 HydrophobicContact CD2-CD1 3.88Å; L28-L39 HydrophobicContact CD2-CG 4.38Å; A35-L39 PolarHBondContact O-N 3.06Å; V36-L39 PolarHBondContact O-N 2.95Å; L39-M42 WeakPolarHBondContact O-CB 3.46Å; L39-M42 PolarHBondContact O-N 3.22Å; L39-M42 VanDerWaalsContact O-N 3.13Å; L39-V43 WeakPolarHBondContact O-CG2 3.18Å; L39-V43 PolarHBondContact O-N 3.3Å; L39-V51 HydrophobicContact CD2-CG1 4.35Å; L39-L54 HydrophobicContact CD2-CB 4.22Å; L39-L54 HydrophobicContact CD2-CD1 3.98Å; L39-L55 HydrophobicContact CD1-CD2 3.84Å; L39-L55 HydrophobicContact CD1-CG 4.49Å; L39-F60 HydrophobicContact CD1-CD1 4.06Å; L39-F60 HydrophobicContact CD1-CE1 4.08Å; L39-F60 HydrophobicContact CD1-CG 4.37Å; L39-F60 HydrophobicContact CD1-CZ 4.44Å; L39-L73 HydrophobicContact CB-CD1 3.73Å; L39-L73 HydrophobicContact CB-CD2 4.31Å; L39-L73 HydrophobicContact CD1-CD1 3.68Å; L39-L73 HydrophobicContact CG-CD1 4.36Å
40M83.3Confident83.9Confident40 Ų4067.6 Ų67.620%0.19734%0.341CS..Hα-helixtrans-54-52.9-173.6163.5-170.3-74.600113.2V36 M42 V43 M44 F66 L73 I76V36-M40 VanDerWaalsContact O-CB 3.28Å; V36-M40 WeakPolarHBondContact O-CB 3.24Å; V36-M40 PolarHBondContact O-N 3.47Å; M40-M42 PolarHBondContact O-N 3.41Å; M40-V43 PolarHBondContact O-N 3.4Å; M40-M44 HydrophobicContact CG-CG 4.3Å; M40-M44 HydrophobicContact CG-SD 3.77Å; M40-M44 VanDerWaalsContact O-CG 3.3Å; M40-M44 WeakPolarHBondContact O-CG 3.35Å; M40-M44 PolarHBondContact O-N 3.38Å; M40-M44 HydrophobicContact SD-SD 4.32Å; M40-F66 HydrophobicContact CE-CD2 4.2Å; M40-F66 HydrophobicContact CE-CE2 3.06Å; M40-F66 HydrophobicContact CE-CZ 3.31Å; M40-L73 HydrophobicContact CB-CD2 4.19Å; M40-I76 HydrophobicContact CE-CD1 4.2Å; M40-I76 HydrophobicContact CE-CG1 4.25Å
41P79.3Confident84.4Confident76 Ų7658.4 Ų58.449%0.49430%0.298SS..Hα-helixtrans-61.3-34.5-179.5-23.233.9000112.7Y37 M44 A45Y37-P41 WeakPolarHBondContact O-CD 3.33Å; P41-M44 PolarHBondContact O-N 3.39Å; P41-A45 WeakPolarHBondContact O-CB 3.33Å; P41-A45 PolarHBondContact O-N 3.46Å
42M85.1Confident84.6Confident43 Ų4356.5 Ų56.521%0.21229%0.29CS..Hα-helixtrans-69.6-40.6177.4-59-176.1-171.400111.5T38 L39 M40 A45 D46 Q47 V51 L54T38-M42 HydrophobicContact CG2-CE 4.41Å; L39-M42 WeakPolarHBondContact O-CB 3.46Å; L39-M42 PolarHBondContact O-N 3.22Å; L39-M42 VanDerWaalsContact O-N 3.13Å; M40-M42 PolarHBondContact O-N 3.41Å; M42-A45 CarbonylContact O-C 3.57Å; M42-A45 PolarHBondContact O-N 3.42Å; M42-D46 PolarHBondContact O-N 3.45Å; M42-D46 VanDerWaalsContact O-N 3.16Å; M42-Q47 HydrophobicContact CB-CB 4.25Å; M42-Q47 PolarHBondContact O-N 3.04Å; M42-V51 HydrophobicContact CB-CG2 3.66Å; M42-L54 HydrophobicContact CE-CD1 4.01Å; M42-L54 HydrophobicContact SD-CD1 3.63Å
43V87.7Confident84.6Confident0 Ų061 Ų610%031%0.311CS..Hα-helixtrans-65-43.8173.8171.40000110.5L39 M40 A45 D46 V51 L73 I76 A77 S82 C85L39-V43 WeakPolarHBondContact O-CG2 3.18Å; L39-V43 PolarHBondContact O-N 3.3Å; M40-V43 PolarHBondContact O-N 3.4Å; V43-A45 PolarHBondContact O-N 3.14Å; V43-D46 PolarHBondContact O-N 3.02Å; V43-D46 VanDerWaalsContact O-N 3.08Å; V43-V51 HydrophobicContact CG2-CG1 4.29Å; V43-V51 HydrophobicContact CG2-CG2 4.07Å; V43-L73 HydrophobicContact CG2-CD2 4.31Å; V43-I76 HydrophobicContact CG1-CG2 4.47Å; V43-A77 HydrophobicContact CG1-CB 3.71Å; V43-S82 WeakPolarHBondContact O-CB 3.45Å; V43-S82 PolarHBondContact O-OG 3.3Å; V43-C85 HydrophobicContact CG1-CB 4.2Å
44M82.3Confident84.6Confident101 Ų10157.3 Ų57.350%0.49829%0.294SS..Hα-helixtrans-61.5-32.9176.1-69175.670.700112.6M40 P41 D46 I76M40-M44 HydrophobicContact CG-CG 4.3Å; M40-M44 HydrophobicContact CG-SD 3.77Å; M40-M44 VanDerWaalsContact O-CG 3.3Å; M40-M44 WeakPolarHBondContact O-CG 3.35Å; M40-M44 PolarHBondContact O-N 3.38Å; M40-M44 HydrophobicContact SD-SD 4.32Å; P41-M44 PolarHBondContact O-N 3.39Å; M44-D46 VanDerWaalsContact C-N 3.34Å; M44-I76 HydrophobicContact CG-CG2 3.47Å; M44-I76 VanDerWaalsContact CG-CG2 3.47Å; M44-I76 HydrophobicContact SD-CG2 4.32Å
45A82.1Confident84.7Confident60 Ų6054 Ų5450%0.49627%0.273SS..THydrogen-bonded Turntrans-89.47.8176.500000114.3P41 M42 V43 Q47P41-A45 WeakPolarHBondContact O-CB 3.33Å; P41-A45 PolarHBondContact O-N 3.46Å; M42-A45 CarbonylContact O-C 3.57Å; M42-A45 PolarHBondContact O-N 3.42Å; V43-A45 PolarHBondContact O-N 3.14Å; A45-Q47 VanDerWaalsContact C-N 3.26Å; A45-Q47 HydrophobicContact CB-CG 4Å; A45-Q47 PolarHBondContact O-N 3.12Å
46D88.3Confident84.5Confident49 Ų4959.4 Ų59.426%0.26230%0.301SS..THydrogen-bonded Turntrans52.734.5-177.6-15626000115.3M42 V43 M44 H48 S82 E84 C85M42-D46 PolarHBondContact O-N 3.45Å; M42-D46 VanDerWaalsContact O-N 3.16Å; V43-D46 PolarHBondContact O-N 3.02Å; V43-D46 VanDerWaalsContact O-N 3.08Å; M44-D46 VanDerWaalsContact C-N 3.34Å; D46-H48 PolarHBondContact O-N 3.11Å; D46-H48 PolarHBondContact O-ND1 2.89Å; D46-S82 WeakPolarHBondContact OD1-CB 3.31Å; D46-E84 PolarHBondContact OD1-N 2.88Å; D46-C85 VanDerWaalsContact C-SG 3.57Å; D46-C85 PolarHBondContact OD1-N 3.27Å; D46-C85 PolarHBondContact OD1-SG 2.87Å
47Q87.8Confident83.9Confident91 Ų9167 Ų6743%0.42534%0.342SS..  trans-79.156.4-179.8-61.9-178.69.400112.6M42 A45 R49 S50 V51M42-Q47 HydrophobicContact CB-CB 4.25Å; M42-Q47 PolarHBondContact O-N 3.04Å; A45-Q47 VanDerWaalsContact C-N 3.26Å; A45-Q47 HydrophobicContact CB-CG 4Å; A45-Q47 PolarHBondContact O-N 3.12Å; Q47-R49 VanDerWaalsContact C-N 3.26Å; Q47-R49 PolarHBondContact O-N 2.93Å; Q47-R49 VanDerWaalsContact O-N 3.11Å; Q47-S50 PolarHBondContact O-N 3.45Å; Q47-S50 VanDerWaalsContact O-N 3.12Å; Q47-V51 WeakPolarHBondContact O-CG2 3.5Å; Q47-V51 PolarHBondContact O-N 3.09Å
48H85.6Confident83.7Confident68 Ų6862.6 Ų62.632%0.31533%0.329SS..Hα-helixtrans-55.3-31.7-172.363-81.2000114.8D46 S52 E84 C85D46-H48 PolarHBondContact O-N 3.11Å; D46-H48 PolarHBondContact O-ND1 2.89Å; H48-S52 WeakPolarHBondContact O-CB 3.09Å; H48-S52 PolarHBondContact O-N 3.05Å; H48-E84 HydrophobicContact CB-CB 3.67Å; H48-C85 VanDerWaalsContact CA-SG 3.56Å; H48-C85 PolarHBondContact N-SG 2.96Å
49R85.4Confident83.7Confident191 Ų19170.3 Ų70.372%0.72136%0.359SS*.Hα-helixtrans-64.9-51.2176.3-64.9-174.1-1741700.9111.5Q47 S52 E53Q47-R49 VanDerWaalsContact C-N 3.26Å; Q47-R49 PolarHBondContact O-N 2.93Å; Q47-R49 VanDerWaalsContact O-N 3.11Å; R49-S52 PolarHBondContact O-N 3.16Å; R49-E53 PolarHBondContact O-N 3.42Å
50S84.4Confident83.8Confident48 Ų4871.2 Ų71.234%0.33636%0.363SS..Hα-helixtrans-61.7-45.5177.4-49.40000111Q47 S52 E53 L54Q47-S50 PolarHBondContact O-N 3.45Å; Q47-S50 VanDerWaalsContact O-N 3.12Å; S50-S52 VanDerWaalsContact C-N 3.33Å; S50-S52 PolarHBondContact O-N 3.08Å; S50-E53 PolarHBondContact O-N 2.99Å; S50-L54 WeakPolarHBondContact O-CG 3.11Å; S50-L54 PolarHBondContact O-N 3.4Å
51V86.6Confident84.1Confident0 Ų072.8 Ų72.80%037%0.372CS..Hα-helixtrans-61.8-40.7177.5176.90000111.2L39 M42 V43 Q47 L54 L55 L88L39-V51 HydrophobicContact CD2-CG1 4.35Å; M42-V51 HydrophobicContact CB-CG2 3.66Å; V43-V51 HydrophobicContact CG2-CG1 4.29Å; V43-V51 HydrophobicContact CG2-CG2 4.07Å; Q47-V51 WeakPolarHBondContact O-CG2 3.5Å; Q47-V51 PolarHBondContact O-N 3.09Å; V51-L54 PolarHBondContact O-N 2.83Å; V51-L55 HydrophobicContact CG1-CD1 3.73Å; V51-L55 HydrophobicContact CG1-CG 4.31Å; V51-L55 WeakPolarHBondContact O-CB 3.41Å; V51-L55 VanDerWaalsContact O-CG 3.24Å; V51-L55 WeakPolarHBondContact O-CG 3.46Å; V51-L55 PolarHBondContact O-N 2.99Å; V51-L88 HydrophobicContact CB-CD2 4.09Å; V51-L88 HydrophobicContact CG1-CD2 3.81Å
52S87.9Confident84.7Confident35 Ų3570 Ų7025%0.24535%0.354CS..Hα-helixtrans-65.6-44.9178.5-174.80000112.7H48 R49 S50 L55 L56 R92H48-S52 WeakPolarHBondContact O-CB 3.09Å; H48-S52 PolarHBondContact O-N 3.05Å; R49-S52 PolarHBondContact O-N 3.16Å; S50-S52 VanDerWaalsContact C-N 3.33Å; S50-S52 PolarHBondContact O-N 3.08Å; S52-L55 PolarHBondContact O-N 3.44Å; S52-L56 WeakPolarHBondContact O-CB 3.28Å; S52-L56 WeakPolarHBondContact O-CD1 3.23Å; S52-L56 WeakPolarHBondContact O-CG 3.2Å; S52-L56 PolarHBondContact O-N 3.15Å; S52-R92 PolarHBondContact O-NH2 3.38Å
53E83.6Confident85Confident136 Ų13669.4 Ų69.464%0.63635%0.352SS*.Hα-helixtrans-60.5-43.8176.6-76.1178.9-172.800111.7R49 S50 L56R49-E53 PolarHBondContact O-N 3.42Å; S50-E53 PolarHBondContact O-N 2.99Å; E53-L56 PolarHBondContact O-N 3.37Å
54L83.6Confident85.2Confident25 Ų2572.1 Ų72.113%0.13136%0.362CS..Hα-helixtrans-67.2-40.1178.2-66.8174.7000112.4V26 L28 L39 M42 S50 V51 S58V26-L54 HydrophobicContact CB-CD2 4.11Å; V26-L54 HydrophobicContact CG1-CD2 4.48Å; V26-L54 WeakPolarHBondContact O-CD2 3.47Å; L28-L54 HydrophobicContact CD1-CB 3.86Å; L28-L54 HydrophobicContact CD1-CD1 4.15Å; L28-L54 HydrophobicContact CD1-CD2 4.49Å; L28-L54 HydrophobicContact CD1-CG 4.4Å; L39-L54 HydrophobicContact CD2-CB 4.22Å; L39-L54 HydrophobicContact CD2-CD1 3.98Å; M42-L54 HydrophobicContact CE-CD1 4.01Å; M42-L54 HydrophobicContact SD-CD1 3.63Å; S50-L54 WeakPolarHBondContact O-CG 3.11Å; S50-L54 PolarHBondContact O-N 3.4Å; V51-L54 PolarHBondContact O-N 2.83Å; L54-S58 WeakPolarHBondContact O-CB 3.18Å
55L84.6Confident85.6Confident5 Ų568 Ų683%0.02634%0.344CS..Hα-helixtrans-74.7-22.7178.7-71.1175.1000113.4L39 V51 S52 N57 F60 L89 R92L39-L55 HydrophobicContact CD1-CD2 3.84Å; L39-L55 HydrophobicContact CD1-CG 4.49Å; V51-L55 HydrophobicContact CG1-CD1 3.73Å; V51-L55 HydrophobicContact CG1-CG 4.31Å; V51-L55 WeakPolarHBondContact O-CB 3.41Å; V51-L55 VanDerWaalsContact O-CG 3.24Å; V51-L55 WeakPolarHBondContact O-CG 3.46Å; V51-L55 PolarHBondContact O-N 2.99Å; S52-L55 PolarHBondContact O-N 3.44Å; L55-N57 VanDerWaalsContact C-N 3.29Å; L55-N57 PolarHBondContact O-N 3.19Å; L55-F60 HydrophobicContact CD2-CB 4.2Å; L55-F60 HydrophobicContact CD2-CD1 3.74Å; L55-F60 HydrophobicContact CD2-CG 4.31Å; L55-L89 HydrophobicContact CD1-CD2 4.13Å; L55-R92 VanDerWaalsContact C-NH1 3.31Å; L55-R92 PolarHBondContact O-NH1 3.11Å
56L81.4Confident85.8Confident113 Ų11365.9 Ų65.959%0.59232%0.324SS*.Hα-helixtrans-60.8-35.6-179.6-95.1154.9000112.7S52 E53S52-L56 WeakPolarHBondContact O-CB 3.28Å; S52-L56 WeakPolarHBondContact O-CD1 3.23Å; S52-L56 WeakPolarHBondContact O-CG 3.2Å; S52-L56 PolarHBondContact O-N 3.15Å; E53-L56 PolarHBondContact O-N 3.37Å
57N72.8Confident85.6Confident160 Ų16065.3 Ų65.386%0.85633%0.329SS*.THydrogen-bonded Turntrans-111.89.4-174.1-64.8-29000113.6L55L55-N57 VanDerWaalsContact C-N 3.29Å; L55-N57 PolarHBondContact O-N 3.19Å
58S78.3Confident85.3Confident31 Ų3172.6 Ų72.622%0.21735%0.353CS..  trans-105.9153-176.377.40000112.7L54 F60L54-S58 WeakPolarHBondContact O-CB 3.18Å; S58-F60 VanDerWaalsContact C-N 3.25Å; S58-F60 WeakPolarHBondContact OG-CB 3.47Å; S58-F60 PolarHBondContact OG-N 2.96Å
59K82.2Confident85.3Confident204 Ų20472.4 Ų72.489%0.88736%0.356SS*.  trans-9018.5167.1-66.1-177.6-179.2172.50112.9D61K59-D61 PolarHBondContact O-N 3.04Å
60F87.8Confident85.4Confident19 Ų1968.6 Ų68.68%0.08335%0.345CS..  trans-61.3130.6-175.2178.2-101.8000111.5L28 N32 A35 V36 L39 L55 S58 V62 Y64 L73L28-F60 HydrophobicContact CD2-CB 3.72Å; L28-F60 HydrophobicContact CD2-CD2 4.31Å; L28-F60 HydrophobicContact CD2-CG 4.07Å; N32-F60 HydrophobicContact CB-CD2 4.29Å; N32-F60 HydrophobicContact CB-CE2 4.22Å; N32-F60 WeakPolarHBondContact OD1-CA 3.22Å; N32-F60 WeakPolarHBondContact OD1-CD2 3.49Å; A35-F60 HydrophobicContact CB-CD2 3.63Å; A35-F60 HydrophobicContact CB-CE2 4.05Å; V36-F60 HydrophobicContact CB-CE2 4.06Å; V36-F60 HydrophobicContact CB-CZ 4.17Å; V36-F60 HydrophobicContact CG2-CE2 4.08Å; V36-F60 HydrophobicContact CG2-CZ 3.66Å; L39-F60 HydrophobicContact CD1-CD1 4.06Å; L39-F60 HydrophobicContact CD1-CE1 4.08Å; L39-F60 HydrophobicContact CD1-CG 4.37Å; L39-F60 HydrophobicContact CD1-CZ 4.44Å; L55-F60 HydrophobicContact CD2-CB 4.2Å; L55-F60 HydrophobicContact CD2-CD1 3.74Å; L55-F60 HydrophobicContact CD2-CG 4.31Å; S58-F60 VanDerWaalsContact C-N 3.25Å; S58-F60 WeakPolarHBondContact OG-CB 3.47Å; S58-F60 PolarHBondContact OG-N 2.96Å; F60-V62 HydrophobicContact CD1-CG1 4.41Å; F60-V62 PolarHBondContact O-N 3.49Å; F60-Y64 HydrophobicContact CE2-CD1 4.43Å; F60-L73 HydrophobicContact CE1-CD1 3.7Å; F60-L73 HydrophobicContact CZ-CD1 3.93Å
61D90.1Very high85.8Confident73 Ų7369 Ų6939%0.3934%0.339SS..  trans-77.3109172.1177.49.4000109.8N32 K59 N63 Y64N32-D61 PolarHBondContact OD1-N 3.38Å; K59-D61 PolarHBondContact O-N 3.04Å; D61-N63 PolarHBondContact O-N 2.9Å; D61-N63 VanDerWaalsContact O-N 3.09Å; D61-N63 PolarHBondContact OD1-N 3.18Å; D61-Y64 WeakPolarHBondContact O-CB 3.37Å; D61-Y64 PolarHBondContact O-N 3.13Å
62V90.4Very high86.1Confident17 Ų1769 Ų6910%0.10334%0.339CS..THydrogen-bonded Turntrans-61.2-18.3179.6-65.70000113.9F60 L89 R92 A94F60-V62 HydrophobicContact CD1-CG1 4.41Å; F60-V62 PolarHBondContact O-N 3.49Å; V62-L89 HydrophobicContact CG1-CD2 4.45Å; V62-R92 HydrophobicContact CG1-CB 4Å; V62-A94 HydrophobicContact CB-CB 4.35Å; V62-A94 HydrophobicContact CG2-CB 4.18Å
63N92.6Very high86.4Confident32 Ų3267.4 Ų67.417%0.17133%0.328CS..THydrogen-bonded Turntrans-95.83.6175-64.8-61.8000113.2D61 A65 G93 A94 N95 Y98D61-N63 PolarHBondContact O-N 2.9Å; D61-N63 VanDerWaalsContact O-N 3.09Å; D61-N63 PolarHBondContact OD1-N 3.18Å; N63-A65 PolarHBondContact O-N 2.87Å; N63-A65 VanDerWaalsContact O-N 3.1Å; N63-G93 PolarHBondContact ND2-O 3.29Å; N63-G93 VanDerWaalsContact ND2-O 3.16Å; N63-A94 WeakPolarHBondContact OD1-CA 3.38Å; N63-N95 PolarHBondContact OD1-N 2.99Å; N63-Y98 HydrophobicContact CB-CD2 4.25Å; N63-Y98 HydrophobicContact CB-CE2 4.28Å
64Y92.4Very high87Confident57 Ų5761 Ų6122%0.22430%0.298CS..  trans-55119.3-179.6-178.2-104.1000111.3N32 E33 V36 F60 D61 F66N32-Y64 HydrophobicContact CB-CD1 3.96Å; N32-Y64 HydrophobicContact CB-CD2 3.47Å; N32-Y64 VanDerWaalsContact CB-CD2 3.47Å; N32-Y64 HydrophobicContact CB-CE1 4.12Å; N32-Y64 HydrophobicContact CB-CE2 3.65Å; N32-Y64 HydrophobicContact CB-CG 3.64Å; E33-Y64 WeakPolarHBondContact CA-OH 3.39Å; E33-Y64 HydrophobicContact CB-CE1 4.37Å; E33-Y64 VanDerWaalsContact CB-OH 3.31Å; E33-Y64 WeakPolarHBondContact CB-OH 3.32Å; V36-Y64 HydrophobicContact CB-CD1 4.24Å; V36-Y64 HydrophobicContact CG1-CD1 4.45Å; V36-Y64 HydrophobicContact CG1-CE1 4.37Å; V36-Y64 HydrophobicContact CG2-CD1 4.39Å; F60-Y64 HydrophobicContact CE2-CD1 4.43Å; D61-Y64 WeakPolarHBondContact O-CB 3.37Å; D61-Y64 PolarHBondContact O-N 3.13Å; Y64-F66 HydrophobicContact CD1-CB 3.99Å; Y64-F66 HydrophobicContact CD1-CD1 4.39Å; Y64-F66 HydrophobicContact CE1-CB 3.62Å
65A90.5Very high87.5Confident13 Ų1359.8 Ų59.811%0.10729%0.291CS..  trans-95.4119.6-178.400000110.5N63 K70 Y98N63-A65 PolarHBondContact O-N 2.87Å; N63-A65 VanDerWaalsContact O-N 3.1Å; A65-K70 HydrophobicContact CB-CB 4.18Å; A65-K70 HydrophobicContact CB-CD 4.35Å; A65-Y98 HydrophobicContact CB-CE1 3.95Å
66F86.3Confident87.9Confident16 Ų1660.5 Ų60.57%0.0730%0.295CS..BIsolated β-bridgetrans-127.9168.4-170.565.8-92.3000112.8V36 M40 Y64 K70 R71 L73 I76V36-F66 HydrophobicContact CB-CD1 4Å; V36-F66 HydrophobicContact CB-CE1 4.38Å; V36-F66 HydrophobicContact CB-CG 4.31Å; V36-F66 HydrophobicContact CG1-CB 3.72Å; V36-F66 HydrophobicContact CG1-CD1 3.54Å; V36-F66 HydrophobicContact CG1-CD2 3.8Å; V36-F66 HydrophobicContact CG1-CE1 4.09Å; V36-F66 HydrophobicContact CG1-CE2 4.39Å; V36-F66 HydrophobicContact CG1-CG 3.36Å; V36-F66 HydrophobicContact CG2-CD1 3.29Å; V36-F66 HydrophobicContact CG2-CE1 3.36Å; V36-F66 HydrophobicContact CG2-CG 4.06Å; V36-F66 HydrophobicContact CG2-CZ 4.23Å; M40-F66 HydrophobicContact CE-CD2 4.2Å; M40-F66 HydrophobicContact CE-CE2 3.06Å; M40-F66 HydrophobicContact CE-CZ 3.31Å; Y64-F66 HydrophobicContact CD1-CB 3.99Å; Y64-F66 HydrophobicContact CD1-CD1 4.39Å; Y64-F66 HydrophobicContact CE1-CB 3.62Å; F66-K70 WeakPolarHBondContact O-CA 3.33Å; F66-K70 PolarHBondContact O-N 2.91Å; F66-R71 WeakPolarHBondContact CD1-O 3.43Å; F66-R71 WeakPolarHBondContact CE1-O 3.37Å; F66-R71 PolarHBondContact N-O 2.92Å; F66-R71 PolarHBondContact O-N 3.3Å; F66-L73 HydrophobicContact CE1-CD2 4.28Å; F66-L73 HydrophobicContact CE1-CG 4.44Å; F66-I76 HydrophobicContact CZ-CD1 4.37Å; F66-I76 HydrophobicContact CZ-CG1 3.97Å
67G83.4Confident88.5Confident37 Ų3755.1 Ų55.138%0.38127%0.267SS..THydrogen-bonded Turntrans66.3-177-176.900000113.6V69 K70G67-V69 VanDerWaalsContact C-N 3.27Å; G67-V69 PolarHBondContact O-N 3.46Å; G67-K70 PolarHBondContact O-N 3.36Å
68R82.4Confident89.5Confident245 Ų24547.5 Ų47.593%0.92523%0.226SC*.THydrogen-bonded Turntrans-66.5-27.9-176.8-64.1-174.8-178.7-170.30.2113.5
69V84Confident90.2Very high63 Ų6348.3 Ų48.338%0.38223%0.228SC..THydrogen-bonded Turntrans-91.8-4.7-176.5-162.40000111.9G67 R71 D100 I101G67-V69 VanDerWaalsContact C-N 3.27Å; G67-V69 PolarHBondContact O-N 3.46Å; V69-R71 HydrophobicContact CB-CG 4.29Å; V69-R71 HydrophobicContact CG1-CG 4.2Å; V69-R71 PolarHBondContact O-N 2.98Å; V69-D100 WeakPolarHBondContact O-CB 3.42Å; V69-I101 HydrophobicContact CB-CG2 4.42Å; V69-I101 HydrophobicContact CG1-CG2 3.94Å; V69-I101 WeakPolarHBondContact O-CG2 3.3Å; V69-I101 PolarHBondContact O-N 3.24Å
70K89.3Confident90.5Very high111 Ų11140.9 Ų40.948%0.48320%0.201SC..THydrogen-bonded Turntrans53.847.4-178.3-64.8-65.5-170177.60113.3A65 F66 G67 I101A65-K70 HydrophobicContact CB-CB 4.18Å; A65-K70 HydrophobicContact CB-CD 4.35Å; F66-K70 WeakPolarHBondContact O-CA 3.33Å; F66-K70 PolarHBondContact O-N 2.91Å; G67-K70 PolarHBondContact O-N 3.36Å; K70-I101 HydrophobicContact CB-CB 4.39Å
71R91.6Very high90.7Very high58 Ų5840.8 Ų40.822%0.21921%0.206CC..BIsolated β-bridgetrans-89.5148.8176.6-74.6-177.8176.4176.80.8111.1F66 V69 H75 D100F66-R71 WeakPolarHBondContact CD1-O 3.43Å; F66-R71 WeakPolarHBondContact CE1-O 3.37Å; F66-R71 PolarHBondContact N-O 2.92Å; F66-R71 PolarHBondContact O-N 3.3Å; V69-R71 HydrophobicContact CB-CG 4.29Å; V69-R71 HydrophobicContact CG1-CG 4.2Å; V69-R71 PolarHBondContact O-N 2.98Å; R71-H75 HydrophobicContact CB-CB 3.98Å; R71-H75 HydrophobicContact CG-CB 4.15Å; R71-D100 HydrophobicContact CG-CB 3.73Å; R71-D100 IonicContact CZ-OD2 3.08Å; R71-D100 IonicContact NE-OD2 3.28Å; R71-D100 PolarHBondContact NE-OD2 3.23Å; R71-D100 IonicContact NH2-OD2 2.64Å
72S93.9Very high90.9Very high0 Ų037.5 Ų37.50%019%0.189CC..  trans-94.2167.4170.870.20000111.7L74 H75 I76S72-L74 PolarHBondContact O-N 3.02Å; S72-L74 PolarHBondContact OG-N 3.24Å; S72-H75 PolarHBondContact N-ND1 3.16Å; S72-H75 WeakPolarHBondContact O-CB 3.34Å; S72-H75 PolarHBondContact O-N 3.35Å; S72-H75 PolarHBondContact OG-ND1 3.34Å; S72-I76 PolarHBondContact O-N 3.46Å
73L92.9Very high91.1Very high1 Ų138 Ų381%0.00519%0.191CC..Hα-helixtrans-59.4-28.3174.6-72.8176.8000112.5V36 L39 M40 V43 F60 F66 H75 I76 A77 L89V36-L73 HydrophobicContact CG2-CD1 4.02Å; V36-L73 HydrophobicContact CG2-CD2 3.73Å; V36-L73 HydrophobicContact CG2-CG 3.63Å; L39-L73 HydrophobicContact CB-CD1 3.73Å; L39-L73 HydrophobicContact CB-CD2 4.31Å; L39-L73 HydrophobicContact CD1-CD1 3.68Å; L39-L73 HydrophobicContact CG-CD1 4.36Å; M40-L73 HydrophobicContact CB-CD2 4.19Å; V43-L73 HydrophobicContact CG2-CD2 4.31Å; F60-L73 HydrophobicContact CE1-CD1 3.7Å; F60-L73 HydrophobicContact CZ-CD1 3.93Å; F66-L73 HydrophobicContact CE1-CD2 4.28Å; F66-L73 HydrophobicContact CE1-CG 4.44Å; L73-H75 VanDerWaalsContact C-N 3.35Å; L73-I76 PolarHBondContact O-N 2.88Å; L73-A77 PolarHBondContact O-N 3.4Å; L73-L89 HydrophobicContact CB-CD1 3.83Å; L73-L89 HydrophobicContact CB-CD2 4.28Å; L73-L89 HydrophobicContact CD1-CD2 4.47Å
74L95.9Very high91.2Very high0 Ų041.2 Ų41.20%021%0.206CC..Hα-helixtrans-65.3-37.6175.1-171.264.5000111.9S72 I76 A77 A78 L86 L89 L90 A94 P106 L122S72-L74 PolarHBondContact O-N 3.02Å; S72-L74 PolarHBondContact OG-N 3.24Å; L74-I76 VanDerWaalsContact C-N 3.35Å; L74-A77 PolarHBondContact O-N 3.44Å; L74-A78 VanDerWaalsContact O-CB 3.3Å; L74-A78 WeakPolarHBondContact O-CB 3.47Å; L74-A78 PolarHBondContact O-N 3Å; L74-L86 HydrophobicContact CD1-CD1 4.19Å; L74-L86 HydrophobicContact CD1-CG 3.79Å; L74-L89 HydrophobicContact CD1-CB 4.22Å; L74-L90 HydrophobicContact CD1-CD2 4.04Å; L74-L90 HydrophobicContact CD1-CG 3.91Å; L74-L90 HydrophobicContact CD2-CD2 3.75Å; L74-A94 HydrophobicContact CB-CB 4.29Å; L74-A94 HydrophobicContact CD2-CB 3.91Å; L74-A94 HydrophobicContact CG-CB 4.48Å; L74-P106 HydrophobicContact CB-CG 4.29Å; L74-P106 HydrophobicContact CD2-CB 4.42Å; L74-P106 HydrophobicContact CD2-CG 3.86Å; L74-P106 HydrophobicContact CG-CB 4.1Å; L74-P106 HydrophobicContact CG-CG 3.82Å; L74-L122 HydrophobicContact CD2-CD2 4.46Å
75H94.6Very high91.2Very high0 Ų038.5 Ų38.50%020%0.195CC..Hα-helixtrans-62.8-41.6172.7-71.184.1000111.8R71 S72 L73 A78 N79 Y98 C104 P106 L109R71-H75 HydrophobicContact CB-CB 3.98Å; R71-H75 HydrophobicContact CG-CB 4.15Å; S72-H75 PolarHBondContact N-ND1 3.16Å; S72-H75 WeakPolarHBondContact O-CB 3.34Å; S72-H75 PolarHBondContact O-N 3.35Å; S72-H75 PolarHBondContact OG-ND1 3.34Å; L73-H75 VanDerWaalsContact C-N 3.35Å; H75-A78 PolarHBondContact O-N 3.1Å; H75-N79 WeakPolarHBondContact O-CB 3.46Å; H75-N79 PolarHBondContact O-N 3.25Å; H75-Y98 PolarHBondContact CE1-O 2.88Å; H75-Y98 PolarHBondContact NE2-O 3.5Å; H75-Y98 VanDerWaalsContact NE2-O 3.14Å; H75-C104 PolarHBondContact NE2-O 3.28Å; H75-P106 WeakPolarHBondContact NE2-CD 3.15Å; H75-L109 HydrophobicContact CB-CD1 3.74Å
76I92.5Very high91.5Very high20 Ų2037.9 Ų37.910%0.10319%0.19CC..Hα-helixtrans-65.5-47178.6-55.8-56.4000110.5M40 V43 M44 F66 S72 L73 L74 A78 N79 C80M40-I76 HydrophobicContact CE-CD1 4.2Å; M40-I76 HydrophobicContact CE-CG1 4.25Å; V43-I76 HydrophobicContact CG1-CG2 4.47Å; M44-I76 HydrophobicContact CG-CG2 3.47Å; M44-I76 VanDerWaalsContact CG-CG2 3.47Å; M44-I76 HydrophobicContact SD-CG2 4.32Å; F66-I76 HydrophobicContact CZ-CD1 4.37Å; F66-I76 HydrophobicContact CZ-CG1 3.97Å; S72-I76 PolarHBondContact O-N 3.46Å; L73-I76 PolarHBondContact O-N 2.88Å; L74-I76 VanDerWaalsContact C-N 3.35Å; I76-A78 VanDerWaalsContact C-N 3.33Å; I76-A78 PolarHBondContact O-N 2.78Å; I76-N79 PolarHBondContact O-N 3.19Å; I76-C80 WeakPolarHBondContact O-CB 3.06Å; I76-C80 PolarHBondContact O-N 3.31Å; I76-C80 PolarHBondContact O-SG 3.08Å
77A94.2Very high92Very high0 Ų037.9 Ų37.90%019%0.191CC..Hα-helixtrans-59-44.9177.400000111.6V43 L73 L74 C80 G81 S82 L86 L89V43-A77 HydrophobicContact CG1-CB 3.71Å; L73-A77 PolarHBondContact O-N 3.4Å; L74-A77 PolarHBondContact O-N 3.44Å; A77-C80 PolarHBondContact O-N 3.33Å; A77-G81 PolarHBondContact O-N 2.92Å; A77-S82 PolarHBondContact O-N 3.25Å; A77-L86 HydrophobicContact CB-CB 3.9Å; A77-L86 HydrophobicContact CB-CD1 4.42Å; A77-L89 HydrophobicContact CB-CD1 4.31Å
78A95.1Very high92.5Very high0 Ų037.3 Ų37.30%018%0.179CC..Hα-helixtrans-66-36.7177.300000113.3L74 H75 I76 L86 P106 A110 Q115 L122L74-A78 VanDerWaalsContact O-CB 3.3Å; L74-A78 WeakPolarHBondContact O-CB 3.47Å; L74-A78 PolarHBondContact O-N 3Å; H75-A78 PolarHBondContact O-N 3.1Å; I76-A78 VanDerWaalsContact C-N 3.33Å; I76-A78 PolarHBondContact O-N 2.78Å; A78-L86 HydrophobicContact CB-CD1 3.84Å; A78-P106 HydrophobicContact CB-CB 3.79Å; A78-P106 VanDerWaalsContact CB-O 3.31Å; A78-P106 WeakPolarHBondContact CB-O 3.37Å; A78-A110 HydrophobicContact CB-CB 4.25Å; A78-Q115 WeakPolarHBondContact O-CG 3.41Å; A78-L122 HydrophobicContact CB-CD1 4.25Å
79N92.3Very high93Very high49 Ų4925.7 Ų25.726%0.26214%0.136SC..Hα-helixtrans-69.9-41.6177.3-17682.1000112.2H75 I76 L109 N113 Q115H75-N79 WeakPolarHBondContact O-CB 3.46Å; H75-N79 PolarHBondContact O-N 3.25Å; I76-N79 PolarHBondContact O-N 3.19Å; N79-L109 HydrophobicContact CB-CB 4.2Å; N79-L109 HydrophobicContact CB-CD1 4.26Å; N79-N113 PolarHBondContact OD1-ND2 3.37Å; N79-Q115 PolarHBondContact O-NE2 3.03Å
80C88.8Confident93.6Very high47 Ų4723.2 Ų23.232%0.31812%0.12SC..Hα-helixtrans-85.4-15.2-176.9-66.90000114.1I76 A77I76-C80 WeakPolarHBondContact O-CB 3.06Å; I76-C80 PolarHBondContact O-N 3.31Å; I76-C80 PolarHBondContact O-SG 3.08Å; A77-C80 PolarHBondContact O-N 3.33Å
81G91.8Very high93.8Very high18 Ų1824.9 Ų24.919%0.18613%0.127CC..THydrogen-bonded Turntrans84.120.6-177.200000114.2A77 V83 Q115A77-G81 PolarHBondContact O-N 2.92Å; G81-V83 VanDerWaalsContact C-N 3.33Å; G81-V83 WeakPolarHBondContact O-CG2 3.33Å; G81-V83 PolarHBondContact O-N 2.96Å; G81-Q115 VanDerWaalsContact CA-OE1 3.3Å
82S93.8Very high93.7Very high4 Ų426.6 Ų26.63%0.02813%0.134CC..  trans-78.777.5-177.4-49.90000111.1V43 D46 A77 E84 C85 L86V43-S82 WeakPolarHBondContact O-CB 3.45Å; V43-S82 PolarHBondContact O-OG 3.3Å; D46-S82 WeakPolarHBondContact OD1-CB 3.31Å; A77-S82 PolarHBondContact O-N 3.25Å; S82-E84 PolarHBondContact O-N 2.62Å; S82-C85 PolarHBondContact O-N 3.3Å; S82-L86 VanDerWaalsContact O-CB 3.23Å; S82-L86 WeakPolarHBondContact O-CB 3.33Å; S82-L86 PolarHBondContact O-N 3.43Å
83V95Very high93.5Very high26 Ų2628.9 Ų28.916%0.15816%0.157CC..Hα-helixtrans-60.6-45.4-169-174.70000112G81 L86 V87 K117 K121G81-V83 VanDerWaalsContact C-N 3.33Å; G81-V83 WeakPolarHBondContact O-CG2 3.33Å; G81-V83 PolarHBondContact O-N 2.96Å; V83-L86 WeakPolarHBondContact O-CB 3.12Å; V83-L86 PolarHBondContact O-N 2.67Å; V83-V87 WeakPolarHBondContact O-CG2 3.35Å; V83-V87 PolarHBondContact O-N 2.78Å; V83-K117 HydrophobicContact CG1-CB 4.16Å; V83-K117 HydrophobicContact CG2-CB 3.5Å; V83-K117 VanDerWaalsContact CG2-CB 3.5Å; V83-K117 HydrophobicContact CG2-CD 4.12Å; V83-K117 HydrophobicContact CG2-CG 4.46Å; V83-K121 HydrophobicContact CG1-CG 4.17Å
84E94.9Very high93.6Very high100 Ų10029.1 Ų29.147%0.46716%0.159SC..Hα-helixtrans-71.4-39.8-175.1-63-60.1165.800111.1D46 H48 S82 L86 L88D46-E84 PolarHBondContact OD1-N 2.88Å; H48-E84 HydrophobicContact CB-CB 3.67Å; S82-E84 PolarHBondContact O-N 2.62Å; E84-L86 VanDerWaalsContact C-N 3.35Å; E84-L88 WeakPolarHBondContact O-CB 3.49Å; E84-L88 PolarHBondContact O-N 3.34Å
85C92.8Very high93.5Very high0 Ų032.4 Ų32.40%018%0.177CC..Hα-helixtrans-64.5-39171.7-66.30000112.2V43 D46 H48 S82 L88 L89V43-C85 HydrophobicContact CG1-CB 4.2Å; D46-C85 VanDerWaalsContact C-SG 3.57Å; D46-C85 PolarHBondContact OD1-N 3.27Å; D46-C85 PolarHBondContact OD1-SG 2.87Å; H48-C85 VanDerWaalsContact CA-SG 3.56Å; H48-C85 PolarHBondContact N-SG 2.96Å; S82-C85 PolarHBondContact O-N 3.3Å; C85-L88 PolarHBondContact O-N 3.32Å; C85-L89 WeakPolarHBondContact O-CB 3.23Å; C85-L89 VanDerWaalsContact O-CG 3.23Å; C85-L89 WeakPolarHBondContact O-CG 3.49Å; C85-L89 PolarHBondContact O-N 3.34Å
86L96.4Very high93.6Very high0 Ų033.1 Ų33.10%018%0.182CC..Hα-helixtrans-61.5-48.3176.9-179.7139.7000111.3L74 A77 A78 S82 V83 E84 L88 L89 L90 C118 K121 L122L74-L86 HydrophobicContact CD1-CD1 4.19Å; L74-L86 HydrophobicContact CD1-CG 3.79Å; A77-L86 HydrophobicContact CB-CB 3.9Å; A77-L86 HydrophobicContact CB-CD1 4.42Å; A78-L86 HydrophobicContact CB-CD1 3.84Å; S82-L86 VanDerWaalsContact O-CB 3.23Å; S82-L86 WeakPolarHBondContact O-CB 3.33Å; S82-L86 PolarHBondContact O-N 3.43Å; V83-L86 WeakPolarHBondContact O-CB 3.12Å; V83-L86 PolarHBondContact O-N 2.67Å; E84-L86 VanDerWaalsContact C-N 3.35Å; L86-L88 VanDerWaalsContact C-N 3.33Å; L86-L88 PolarHBondContact O-N 3.34Å; L86-L89 PolarHBondContact O-N 3.01Å; L86-L90 HydrophobicContact CD2-CD1 3.56Å; L86-L90 HydrophobicContact CG-CD1 4.25Å; L86-L90 WeakPolarHBondContact O-CG 3.38Å; L86-L90 PolarHBondContact O-N 3.1Å; L86-C118 HydrophobicContact CD1-CB 3.92Å; L86-K121 HydrophobicContact CD2-CB 3.72Å; L86-L122 HydrophobicContact CD1-CD1 4.24Å; L86-L122 HydrophobicContact CD1-CD2 4.25Å; L86-L122 HydrophobicContact CD1-CG 4.14Å; L86-L122 HydrophobicContact CD2-CD2 4.42Å; L86-L122 HydrophobicContact CD2-CG 4.26Å
87V95.9Very high93.7Very high16 Ų1634.2 Ų34.210%0.09719%0.188CC..Hα-helixtrans-62.7-41.2176.61720000111.2V83 L90 K91 K121V83-V87 WeakPolarHBondContact O-CG2 3.35Å; V83-V87 PolarHBondContact O-N 2.78Å; V87-L90 PolarHBondContact O-N 3.22Å; V87-K91 HydrophobicContact CG1-CD 4.12Å; V87-K91 HydrophobicContact CG1-CG 4.45Å; V87-K91 WeakPolarHBondContact O-CB 3.19Å; V87-K91 WeakPolarHBondContact O-CG 3.41Å; V87-K91 PolarHBondContact O-N 3.15Å; V87-K121 HydrophobicContact CG2-CB 4.04Å; V87-K121 HydrophobicContact CG2-CD 3.98Å; V87-K121 HydrophobicContact CG2-CG 3.64Å
88L93.8Very high93.7Very high26 Ų2638 Ų3814%0.13620%0.203CC..Hα-helixtrans-59.4-47.7175.8175.968.2000111.6V51 E84 C85 L86 K91 R92V51-L88 HydrophobicContact CB-CD2 4.09Å; V51-L88 HydrophobicContact CG1-CD2 3.81Å; E84-L88 WeakPolarHBondContact O-CB 3.49Å; E84-L88 PolarHBondContact O-N 3.34Å; C85-L88 PolarHBondContact O-N 3.32Å; L86-L88 VanDerWaalsContact C-N 3.33Å; L86-L88 PolarHBondContact O-N 3.34Å; L88-K91 PolarHBondContact O-N 2.98Å; L88-R92 WeakPolarHBondContact O-CG 3.41Å; L88-R92 PolarHBondContact O-N 3.43Å; L88-R92 VanDerWaalsContact O-N 3.15Å
89L94.1Very high93.7Very high1 Ų142.2 Ų42.21%0.00522%0.222CC..Hα-helixtrans-63.2-43.3179.4-70.5167.3000111.5L55 V62 L73 L74 A77 C85 L86 R92 G93 A94L55-L89 HydrophobicContact CD1-CD2 4.13Å; V62-L89 HydrophobicContact CG1-CD2 4.45Å; L73-L89 HydrophobicContact CB-CD1 3.83Å; L73-L89 HydrophobicContact CB-CD2 4.28Å; L73-L89 HydrophobicContact CD1-CD2 4.47Å; L74-L89 HydrophobicContact CD1-CB 4.22Å; A77-L89 HydrophobicContact CB-CD1 4.31Å; C85-L89 WeakPolarHBondContact O-CB 3.23Å; C85-L89 VanDerWaalsContact O-CG 3.23Å; C85-L89 WeakPolarHBondContact O-CG 3.49Å; C85-L89 PolarHBondContact O-N 3.34Å; L86-L89 PolarHBondContact O-N 3.01Å; L89-R92 CarbonylContact O-C 3.57Å; L89-R92 PolarHBondContact O-N 3.14Å; L89-R92 VanDerWaalsContact O-N 3.11Å; L89-G93 PolarHBondContact O-N 2.91Å; L89-A94 HydrophobicContact CB-CB 4.08Å; L89-A94 WeakPolarHBondContact O-CB 3.22Å; L89-A94 PolarHBondContact O-N 3.47Å
90L95.1Very high93.8Very high11 Ų1140.3 Ų40.36%0.05821%0.212CC..Hα-helixtrans-61.3-44.7175.7-70.9168.9000112.1L74 L86 V87 R92 G93 P96 L122 Y125L74-L90 HydrophobicContact CD1-CD2 4.04Å; L74-L90 HydrophobicContact CD1-CG 3.91Å; L74-L90 HydrophobicContact CD2-CD2 3.75Å; L86-L90 HydrophobicContact CD2-CD1 3.56Å; L86-L90 HydrophobicContact CG-CD1 4.25Å; L86-L90 WeakPolarHBondContact O-CG 3.38Å; L86-L90 PolarHBondContact O-N 3.1Å; V87-L90 PolarHBondContact O-N 3.22Å; L90-R92 PolarHBondContact O-N 2.92Å; L90-G93 PolarHBondContact O-N 3.49Å; L90-P96 HydrophobicContact CD2-CB 3.98Å; L90-P96 HydrophobicContact CD2-CG 4.4Å; L90-L122 HydrophobicContact CD1-CD2 4.27Å; L90-L122 HydrophobicContact CD2-CD2 4.39Å; L90-Y125 HydrophobicContact CB-CD1 3.71Å; L90-Y125 HydrophobicContact CB-CE1 3.87Å; L90-Y125 HydrophobicContact CB-CG 4.06Å; L90-Y125 HydrophobicContact CD1-CD1 4.4Å; L90-Y125 HydrophobicContact CD1-CD2 3.95Å; L90-Y125 HydrophobicContact CD1-CG 3.88Å; L90-Y125 HydrophobicContact CG-CD1 4.48Å; L90-Y125 HydrophobicContact CG-CG 4.39Å
91K93.4Very high94.1Very high146 Ų14643.2 Ų43.264%0.63522%0.223SC*.Hα-helixtrans-60.8-25.2174.7-75.8177.9177.9176.80113.3V87 L88 G93 Y125V87-K91 HydrophobicContact CG1-CD 4.12Å; V87-K91 HydrophobicContact CG1-CG 4.45Å; V87-K91 WeakPolarHBondContact O-CB 3.19Å; V87-K91 WeakPolarHBondContact O-CG 3.41Å; V87-K91 PolarHBondContact O-N 3.15Å; L88-K91 PolarHBondContact O-N 2.98Å; K91-G93 VanDerWaalsContact C-N 3.32Å; K91-Y125 WeakPolarHBondContact CE-OH 3.44Å; K91-Y125 HydrophobicContact CG-CE1 4.33Å; K91-Y125 WeakPolarHBondContact CG-OH 3.42Å
92R90Very high94Very high93 Ų9344.3 Ų44.335%0.35123%0.228SC..THydrogen-bonded Turntrans-89.48.3176.2-66-62.1-16795.413.6113.5S52 L55 V62 L88 L89 L90S52-R92 PolarHBondContact O-NH2 3.38Å; L55-R92 VanDerWaalsContact C-NH1 3.31Å; L55-R92 PolarHBondContact O-NH1 3.11Å; V62-R92 HydrophobicContact CG1-CB 4Å; L88-R92 WeakPolarHBondContact O-CG 3.41Å; L88-R92 PolarHBondContact O-N 3.43Å; L88-R92 VanDerWaalsContact O-N 3.15Å; L89-R92 CarbonylContact O-C 3.57Å; L89-R92 PolarHBondContact O-N 3.14Å; L89-R92 VanDerWaalsContact O-N 3.11Å; L90-R92 PolarHBondContact O-N 2.92Å
93G90.7Very high94Very high48 Ų4844.3 Ų44.350%0.49523%0.228SC..THydrogen-bonded Turntrans90.119.3175.800000114.7N63 L89 L90 K91 N95N63-G93 PolarHBondContact ND2-O 3.29Å; N63-G93 VanDerWaalsContact ND2-O 3.16Å; L89-G93 PolarHBondContact O-N 2.91Å; L90-G93 PolarHBondContact O-N 3.49Å; K91-G93 VanDerWaalsContact C-N 3.32Å; G93-N95 PolarHBondContact O-N 2.96Å
94A94.1Very high94.1Very high6 Ų643.4 Ų43.45%0.0522%0.223CC..  trans-64130.5168.600000109.8V62 N63 L74 L89 P96V62-A94 HydrophobicContact CB-CB 4.35Å; V62-A94 HydrophobicContact CG2-CB 4.18Å; N63-A94 WeakPolarHBondContact OD1-CA 3.38Å; L74-A94 HydrophobicContact CB-CB 4.29Å; L74-A94 HydrophobicContact CD2-CB 3.91Å; L74-A94 HydrophobicContact CG-CB 4.48Å; L89-A94 HydrophobicContact CB-CB 4.08Å; L89-A94 WeakPolarHBondContact O-CB 3.22Å; L89-A94 PolarHBondContact O-N 3.47Å; A94-P96 WeakPolarHBondContact O-CD 3.42Å
95N94.8Very high94.1Very high69 Ų6938.7 Ų38.737%0.36920%0.201SC..  trans-78.8114.6-179.1179.31.9000109.9N63 G93 N97 Y98N63-N95 PolarHBondContact OD1-N 2.99Å; G93-N95 PolarHBondContact O-N 2.96Å; N95-N97 PolarHBondContact O-N 3.46Å; N95-N97 VanDerWaalsContact O-N 3.15Å; N95-N97 WeakPolarHBondContact OD1-CB 3.47Å; N95-N97 PolarHBondContact OD1-N 3.2Å; N95-Y98 WeakPolarHBondContact O-CB 3.43Å; N95-Y98 PolarHBondContact O-N 3.48Å
96P95.1Very high94.3Very high15 Ų1538.7 Ų38.710%0.09720%0.201CC..THydrogen-bonded Turntrans-66-14.317928.3-35000113.7L90 A94 P106 L122 Y125 A127L90-P96 HydrophobicContact CD2-CB 3.98Å; L90-P96 HydrophobicContact CD2-CG 4.4Å; A94-P96 WeakPolarHBondContact O-CD 3.42Å; P96-P106 WeakPolarHBondContact O-CD 3.41Å; P96-L122 HydrophobicContact CB-CD2 4.07Å; P96-Y125 WeakPolarHBondContact CG-O 3.39Å; P96-A127 HydrophobicContact CB-CB 3.98Å
97N95.9Very high94.2Very high43 Ų4338.7 Ų38.723%0.2320%0.201CC..THydrogen-bonded Turntrans-104.37.3-178.8-64-29.3000113N95 Q99 A127 D128 I131N95-N97 PolarHBondContact O-N 3.46Å; N95-N97 VanDerWaalsContact O-N 3.15Å; N95-N97 WeakPolarHBondContact OD1-CB 3.47Å; N95-N97 PolarHBondContact OD1-N 3.2Å; N97-Q99 PolarHBondContact O-N 3.06Å; N97-A127 WeakPolarHBondContact OD1-CA 3.37Å; N97-D128 PolarHBondContact OD1-N 3.27Å; N97-I131 HydrophobicContact CB-CD1 3.54Å
98Y94.4Very high94.2Very high81 Ų8138.1 Ų38.132%0.31820%0.197SC..  trans-61.7129.4176.2-160.9-78.2000109.8N63 A65 H75 N95 P106N63-Y98 HydrophobicContact CB-CD2 4.25Å; N63-Y98 HydrophobicContact CB-CE2 4.28Å; A65-Y98 HydrophobicContact CB-CE1 3.95Å; H75-Y98 PolarHBondContact CE1-O 2.88Å; H75-Y98 PolarHBondContact NE2-O 3.5Å; H75-Y98 VanDerWaalsContact NE2-O 3.14Å; N95-Y98 WeakPolarHBondContact O-CB 3.43Å; N95-Y98 PolarHBondContact O-N 3.48Å; Y98-P106 WeakPolarHBondContact O-CD 3.21Å
99Q95.4Very high94.2Very high88 Ų8837 Ų3741%0.41119%0.192SC..  trans-99.7135.4179.9-70.1179.7-78.700111.1N97 G103 C104 T105 I131 C132N97-Q99 PolarHBondContact O-N 3.06Å; Q99-G103 PolarHBondContact NE2-O 3.49Å; Q99-C104 WeakPolarHBondContact CA-O 3.3Å; Q99-T105 HydrophobicContact CG-CG2 3.78Å; Q99-I131 HydrophobicContact CG-CG2 4.07Å; Q99-I131 VanDerWaalsContact NE2-CG2 3.35Å; Q99-C132 PolarHBondContact NE2-O 2.93Å
100D93.7Very high94.2Very high8 Ų837 Ų374%0.04319%0.192CC..  trans-73.7-179.7168.582.55000111.4V69 R71 S102 G103 C104V69-D100 WeakPolarHBondContact O-CB 3.42Å; R71-D100 HydrophobicContact CG-CB 3.73Å; R71-D100 IonicContact CZ-OD2 3.08Å; R71-D100 IonicContact NE-OD2 3.28Å; R71-D100 PolarHBondContact NE-OD2 3.23Å; R71-D100 IonicContact NH2-OD2 2.64Å; D100-S102 PolarHBondContact O-N 2.95Å; D100-S102 WeakPolarHBondContact OD1-CA 3.41Å; D100-S102 WeakPolarHBondContact OD1-CB 3.15Å; D100-S102 PolarHBondContact OD1-N 2.98Å; D100-S102 PolarHBondContact OD1-OG 3.49Å; D100-G103 PolarHBondContact O-N 2.86Å; D100-G103 PolarHBondContact OD1-N 3.4Å; D100-C104 PolarHBondContact N-O 2.94Å; D100-C104 WeakPolarHBondContact OD1-CB 3.49Å; D100-C104 PolarHBondContact OD1-N 3.42Å; D100-C104 VanDerWaalsContact OD1-N 3.09Å
101I93.8Very high94.1Very high109 Ų10936.5 Ų36.556%0.55919%0.189SC*.THydrogen-bonded Turntrans-59.6-23.4-176.7-160.2168.3000113.6V69 K70 G103 N134V69-I101 HydrophobicContact CB-CG2 4.42Å; V69-I101 HydrophobicContact CG1-CG2 3.94Å; V69-I101 WeakPolarHBondContact O-CG2 3.3Å; V69-I101 PolarHBondContact O-N 3.24Å; K70-I101 HydrophobicContact CB-CB 4.39Å; I101-G103 VanDerWaalsContact C-N 3.31Å; I101-N134 PolarHBondContact O-ND2 3.42Å
102S91.8Very high94.1Very high41 Ų4135.4 Ų35.429%0.28718%0.181SC..THydrogen-bonded Turntrans-88.91.9177.769.70000113D100 C104 N133 N134D100-S102 PolarHBondContact O-N 2.95Å; D100-S102 WeakPolarHBondContact OD1-CA 3.41Å; D100-S102 WeakPolarHBondContact OD1-CB 3.15Å; D100-S102 PolarHBondContact OD1-N 2.98Å; D100-S102 PolarHBondContact OD1-OG 3.49Å; S102-C104 VanDerWaalsContact C-N 3.28Å; S102-C104 PolarHBondContact OG-SG 3.33Å; S102-N133 WeakPolarHBondContact O-CB 3.43Å; S102-N134 VanDerWaalsContact C-CG 3.45Å; S102-N134 WeakPolarHBondContact O-CB 3.3Å; S102-N134 VanDerWaalsContact O-CG 3.25Å; S102-N134 PolarHBondContact O-N 3.47Å; S102-N134 PolarHBondContact O-OD1 3.33Å
103G93.6Very high94.1Very high3 Ų333.9 Ų33.93%0.03118%0.18CC..SBendtrans80.16.1-173.600000113.3Q99 D100 I101 N133Q99-G103 PolarHBondContact NE2-O 3.49Å; D100-G103 PolarHBondContact O-N 2.86Å; D100-G103 PolarHBondContact OD1-N 3.4Å; I101-G103 VanDerWaalsContact C-N 3.31Å; G103-N133 WeakPolarHBondContact O-CA 3.27Å
104C95.3Very high94.1Very high8 Ų832.6 Ų32.65%0.05417%0.166CC..  trans-80.6133-178.2-70.40000110.8H75 Q99 D100 S102 H108H75-C104 PolarHBondContact NE2-O 3.28Å; Q99-C104 WeakPolarHBondContact CA-O 3.3Å; D100-C104 PolarHBondContact N-O 2.94Å; D100-C104 WeakPolarHBondContact OD1-CB 3.49Å; D100-C104 PolarHBondContact OD1-N 3.42Å; D100-C104 VanDerWaalsContact OD1-N 3.09Å; S102-C104 VanDerWaalsContact C-N 3.28Å; S102-C104 PolarHBondContact OG-SG 3.33Å; C104-H108 HydrophobicContact CB-CB 4.29Å
105T96.1Very high94.1Very high0 Ų034.9 Ų34.90%018%0.176CC..  trans-91166.6171.472.10000111.7Q99 L107 H108 L109 I131Q99-T105 HydrophobicContact CG-CG2 3.78Å; T105-L107 PolarHBondContact O-N 3.28Å; T105-L107 PolarHBondContact OG1-N 3.19Å; T105-H108 PolarHBondContact N-ND1 3.13Å; T105-H108 WeakPolarHBondContact O-CB 3.47Å; T105-H108 PolarHBondContact O-N 2.96Å; T105-H108 PolarHBondContact OG1-ND1 3.48Å; T105-L109 PolarHBondContact O-N 3.06Å; T105-I131 HydrophobicContact CG2-CB 4.12Å; T105-I131 HydrophobicContact CG2-CD1 4.04Å; T105-I131 HydrophobicContact CG2-CG2 3.64Å
106P96.1Very high94Very high0 Ų036.2 Ų36.20%018%0.178CC..Hα-helixtrans-53-34.9170.2-27.135.1000113.2L74 H75 A78 P96 Y98 H108 L109 A110 L122L74-P106 HydrophobicContact CB-CG 4.29Å; L74-P106 HydrophobicContact CD2-CB 4.42Å; L74-P106 HydrophobicContact CD2-CG 3.86Å; L74-P106 HydrophobicContact CG-CB 4.1Å; L74-P106 HydrophobicContact CG-CG 3.82Å; H75-P106 WeakPolarHBondContact NE2-CD 3.15Å; A78-P106 HydrophobicContact CB-CB 3.79Å; A78-P106 VanDerWaalsContact CB-O 3.31Å; A78-P106 WeakPolarHBondContact CB-O 3.37Å; P96-P106 WeakPolarHBondContact O-CD 3.41Å; Y98-P106 WeakPolarHBondContact O-CD 3.21Å; P106-H108 PolarHBondContact O-N 3.07Å; P106-L109 PolarHBondContact O-N 3.06Å; P106-A110 WeakPolarHBondContact O-CB 3.48Å; P106-A110 PolarHBondContact O-N 3.24Å; P106-L122 HydrophobicContact CB-CD1 4.1Å; P106-L122 HydrophobicContact CB-CD2 4.08Å
107L95.9Very high93.9Very high1 Ų142.9 Ų42.91%0.00521%0.206CC..Hα-helixtrans-64.3-39.1177.5-17564.3000112.2T105 L109 A110 A111 M119 L122 L123 A127 V129 A139 L155T105-L107 PolarHBondContact O-N 3.28Å; T105-L107 PolarHBondContact OG1-N 3.19Å; L107-L109 PolarHBondContact O-N 2.89Å; L107-A110 PolarHBondContact O-N 3.02Å; L107-A111 WeakPolarHBondContact O-CB 3.43Å; L107-A111 PolarHBondContact O-N 3.09Å; L107-M119 HydrophobicContact CD1-CB 4.33Å; L107-M119 HydrophobicContact CD1-CE 4.45Å; L107-M119 HydrophobicContact CD1-CG 4.18Å; L107-L122 HydrophobicContact CB-CD1 4.37Å; L107-L122 HydrophobicContact CD1-CB 4.29Å; L107-L122 HydrophobicContact CD1-CD1 4.37Å; L107-L123 HydrophobicContact CD2-CD2 4.32Å; L107-A127 HydrophobicContact CD2-CB 4.26Å; L107-V129 HydrophobicContact CD2-CB 4.49Å; L107-V129 HydrophobicContact CD2-CG1 4Å; L107-A139 HydrophobicContact CD2-CB 4.14Å; L107-A139 HydrophobicContact CG-CB 4.05Å; L107-L155 HydrophobicContact CD2-CD1 4.37Å
108H94.8Very high93.9Very high3 Ų340.9 Ų40.91%0.01420%0.195CC..Hα-helixtrans-60.7-44.6174.3-66.491.1000111.7C104 T105 P106 A111 R112 I131 L137 T138 W142C104-H108 HydrophobicContact CB-CB 4.29Å; T105-H108 PolarHBondContact N-ND1 3.13Å; T105-H108 WeakPolarHBondContact O-CB 3.47Å; T105-H108 PolarHBondContact O-N 2.96Å; T105-H108 PolarHBondContact OG1-ND1 3.48Å; P106-H108 PolarHBondContact O-N 3.07Å; H108-A111 PolarHBondContact O-N 3.06Å; H108-R112 VanDerWaalsContact O-CB 3.3Å; H108-R112 WeakPolarHBondContact O-CB 3.49Å; H108-R112 PolarHBondContact O-N 3.49Å; H108-I131 PolarHBondContact CE1-O 2.92Å; H108-I131 PolarHBondContact NE2-O 3.1Å; H108-I131 VanDerWaalsContact NE2-O 3.08Å; H108-L137 PolarHBondContact NE2-O 2.91Å; H108-T138 WeakPolarHBondContact NE2-CA 3.4Å; H108-W142 AromaticContact CD2-CD1 3.62Å; H108-W142 AromaticContact CD2-NE1 3.62Å
109L93.7Very high93.9Very high4 Ų437.3 Ų37.32%0.02118%0.181CC..Hα-helixtrans-68.9-37179.7-59.8-177.3000112.1H75 N79 T105 P106 L107 N113H75-L109 HydrophobicContact CB-CD1 3.74Å; N79-L109 HydrophobicContact CB-CB 4.2Å; N79-L109 HydrophobicContact CB-CD1 4.26Å; T105-L109 PolarHBondContact O-N 3.06Å; P106-L109 PolarHBondContact O-N 3.06Å; L107-L109 PolarHBondContact O-N 2.89Å; L109-N113 PolarHBondContact O-N 3.46Å; L109-N113 VanDerWaalsContact O-N 3.12Å; L109-N113 PolarHBondContact O-ND2 3.47Å
110A94.8Very high93.8Very high0 Ų034.5 Ų34.50%018%0.177CC..Hα-helixtrans-65.2-4417400000111.3A78 P106 L107 N113 G114 Q115 C118 M119 L122A78-A110 HydrophobicContact CB-CB 4.25Å; P106-A110 WeakPolarHBondContact O-CB 3.48Å; P106-A110 PolarHBondContact O-N 3.24Å; L107-A110 PolarHBondContact O-N 3.02Å; A110-N113 PolarHBondContact O-N 2.83Å; A110-G114 PolarHBondContact O-N 2.98Å; A110-Q115 HydrophobicContact CB-CB 4.22Å; A110-Q115 PolarHBondContact O-N 2.57Å; A110-C118 HydrophobicContact CB-CB 4.31Å; A110-M119 HydrophobicContact CB-CG 3.58Å; A110-L122 HydrophobicContact CB-CD1 4.09Å
111A93.4Very high93.8Very high0 Ų037.2 Ų37.20%019%0.188CC..Hα-helixtrans-62.5-48.8176.300000112.1L107 H108 N113 G114 M119 A139 W142 L143L107-A111 WeakPolarHBondContact O-CB 3.43Å; L107-A111 PolarHBondContact O-N 3.09Å; H108-A111 PolarHBondContact O-N 3.06Å; A111-N113 VanDerWaalsContact C-N 3.31Å; A111-N113 PolarHBondContact O-N 2.79Å; A111-G114 PolarHBondContact O-N 3.06Å; A111-M119 HydrophobicContact CB-CE 4.23Å; A111-M119 HydrophobicContact CB-SD 4.16Å; A111-A139 HydrophobicContact CB-CB 4.27Å; A111-W142 HydrophobicContact CB-CB 4.17Å; A111-L143 HydrophobicContact CB-CD2 3.78Å; A111-L143 HydrophobicContact CB-CG 3.99Å
112R91.6Very high93.9Very high123 Ų12332 Ų3246%0.46416%0.161SC..Hα-helixtrans-56.9-41.6177.8179.3178.9173.4168.6-0.2112.7H108 W142 N146H108-R112 VanDerWaalsContact O-CB 3.3Å; H108-R112 WeakPolarHBondContact O-CB 3.49Å; H108-R112 PolarHBondContact O-N 3.49Å; R112-W142 HydrophobicContact CB-CB 4.32Å; R112-W142 HydrophobicContact CB-CD2 4.15Å; R112-W142 HydrophobicContact CB-CE3 3.9Å; R112-W142 HydrophobicContact CB-CG 4.35Å; R112-W142 HydrophobicContact CG-CD2 4.43Å; R112-W142 HydrophobicContact CG-CE3 3.71Å; R112-W142 HydrophobicContact CG-CZ3 4.06Å; R112-N146 PolarHBondContact O-ND2 2.9Å
113N90.1Very high93.9Very high62 Ų6231.3 Ų31.333%0.33215%0.154SC..THydrogen-bonded Turntrans-92.53.2-178.5-64.3-63.6000113.9N79 L109 A110 A111 Q115N79-N113 PolarHBondContact OD1-ND2 3.37Å; L109-N113 PolarHBondContact O-N 3.46Å; L109-N113 VanDerWaalsContact O-N 3.12Å; L109-N113 PolarHBondContact O-ND2 3.47Å; A110-N113 PolarHBondContact O-N 2.83Å; A111-N113 VanDerWaalsContact C-N 3.31Å; A111-N113 PolarHBondContact O-N 2.79Å; N113-Q115 HydrophobicContact CB-CG 3.94Å
114G91.3Very high93.9Very high20 Ų2036.9 Ų36.921%0.20618%0.179CC..THydrogen-bonded Turntrans69.729.5177.500000114.8A110 A111 K116A110-G114 PolarHBondContact O-N 2.98Å; A111-G114 PolarHBondContact O-N 3.06Å; G114-K116 PolarHBondContact O-N 2.79Å
115Q93.9Very high93.8Very high54 Ų5440.4 Ų40.425%0.25219%0.192SC..  trans-83.174.7-173-57.9-681.500112.1A78 N79 G81 A110 N113 K117 C118 M119A78-Q115 WeakPolarHBondContact O-CG 3.41Å; N79-Q115 PolarHBondContact O-NE2 3.03Å; G81-Q115 VanDerWaalsContact CA-OE1 3.3Å; A110-Q115 HydrophobicContact CB-CB 4.22Å; A110-Q115 PolarHBondContact O-N 2.57Å; N113-Q115 HydrophobicContact CB-CG 3.94Å; Q115-K117 PolarHBondContact O-N 3.33Å; Q115-C118 HydrophobicContact CB-CB 3.92Å; Q115-C118 PolarHBondContact O-N 2.94Å; Q115-C118 VanDerWaalsContact O-N 3.07Å; Q115-M119 PolarHBondContact O-N 3.5Å
116K93.4Very high93.6Very high97 Ų9747 Ų4742%0.42223%0.227SC..Hα-helixtrans-45-54.5-174.5-169.5160.9-169.2171.80114.4G114 C118 M119 G120 E150 L151 D154G114-K116 PolarHBondContact O-N 2.79Å; K116-C118 PolarHBondContact O-N 3.49Å; K116-M119 PolarHBondContact O-N 2.8Å; K116-G120 PolarHBondContact O-N 3.29Å; K116-E150 IonicContact NZ-OE2 3.19Å; K116-E150 PolarHBondContact NZ-OE2 3.01Å; K116-L151 HydrophobicContact CB-CD2 3.49Å; K116-L151 VanDerWaalsContact CB-CD2 3.49Å; K116-L151 HydrophobicContact CD-CD2 3.79Å; K116-L151 HydrophobicContact CG-CD2 3.38Å; K116-D154 WeakPolarHBondContact CE-OD2 3.44Å
117K93.8Very high93.4Very high156 Ų15647.4 Ų47.468%0.67823%0.231SC*.Hα-helixtrans-66.1-38.8-176.8-67.2-177.6-179.1179.60112.2V83 Q115 G120 K121V83-K117 HydrophobicContact CG1-CB 4.16Å; V83-K117 HydrophobicContact CG2-CB 3.5Å; V83-K117 VanDerWaalsContact CG2-CB 3.5Å; V83-K117 HydrophobicContact CG2-CD 4.12Å; V83-K117 HydrophobicContact CG2-CG 4.46Å; Q115-K117 PolarHBondContact O-N 3.33Å; K117-G120 PolarHBondContact O-N 3.49Å; K117-K121 WeakPolarHBondContact O-CG 3.48Å; K117-K121 PolarHBondContact O-N 3.02Å
118C94.7Very high93.3Very high0 Ų050.6 Ų50.60%025%0.248CC..Hα-helixtrans-66.6-42.3176.8-70.90000111.1L86 A110 Q115 K116 K121 L122L86-C118 HydrophobicContact CD1-CB 3.92Å; A110-C118 HydrophobicContact CB-CB 4.31Å; Q115-C118 HydrophobicContact CB-CB 3.92Å; Q115-C118 PolarHBondContact O-N 2.94Å; Q115-C118 VanDerWaalsContact O-N 3.07Å; K116-C118 PolarHBondContact O-N 3.49Å; C118-K121 PolarHBondContact O-N 3.07Å; C118-L122 WeakPolarHBondContact O-CB 3.41Å; C118-L122 VanDerWaalsContact O-CG 3.27Å; C118-L122 WeakPolarHBondContact O-CG 3.33Å; C118-L122 PolarHBondContact O-N 3.19Å
119M94.8Very high93.1Very high6 Ų651 Ų513%0.0325%0.25CS..Hα-helixtrans-59.3-49.3174.6-70.2-179.763.400111.7L107 A110 A111 Q115 K116 K121 L122 L123 L143 L151 L155L107-M119 HydrophobicContact CD1-CB 4.33Å; L107-M119 HydrophobicContact CD1-CE 4.45Å; L107-M119 HydrophobicContact CD1-CG 4.18Å; A110-M119 HydrophobicContact CB-CG 3.58Å; A111-M119 HydrophobicContact CB-CE 4.23Å; A111-M119 HydrophobicContact CB-SD 4.16Å; Q115-M119 PolarHBondContact O-N 3.5Å; K116-M119 PolarHBondContact O-N 2.8Å; M119-K121 VanDerWaalsContact C-N 3.3Å; M119-K121 PolarHBondContact O-N 2.87Å; M119-L122 PolarHBondContact O-N 3.12Å; M119-L122 VanDerWaalsContact O-N 3.13Å; M119-L123 WeakPolarHBondContact O-CG 3.44Å; M119-L123 PolarHBondContact O-N 2.9Å; M119-L143 HydrophobicContact CE-CD1 4.02Å; M119-L143 HydrophobicContact CE-CD2 4.16Å; M119-L143 HydrophobicContact SD-CD2 4.24Å; M119-L151 HydrophobicContact CE-CB 4.31Å; M119-L151 HydrophobicContact SD-CB 4.2Å; M119-L151 HydrophobicContact SD-CD1 3.86Å; M119-L151 HydrophobicContact SD-CD2 4.47Å; M119-L151 HydrophobicContact SD-CG 4.41Å; M119-L155 HydrophobicContact CE-CD1 4.29Å
120G92.6Very high92.9Very high30 Ų3054.1 Ų54.131%0.30927%0.267SS..Hα-helixtrans-56.3-43.9177.200000112.3K116 K117 L123 E124K116-G120 PolarHBondContact O-N 3.29Å; K117-G120 PolarHBondContact O-N 3.49Å; G120-L123 PolarHBondContact O-N 3.33Å; G120-E124 WeakPolarHBondContact O-CG 3.31Å; G120-E124 PolarHBondContact O-N 3.48Å
121K95.1Very high92.8Very high65 Ų6555.5 Ų55.528%0.28327%0.274SS..Hα-helixtrans-68.1-35.8175.7-67.7-50.4-174.9-163.10114V83 L86 V87 K117 C118 M119 E124 Y125V83-K121 HydrophobicContact CG1-CG 4.17Å; L86-K121 HydrophobicContact CD2-CB 3.72Å; V87-K121 HydrophobicContact CG2-CB 4.04Å; V87-K121 HydrophobicContact CG2-CD 3.98Å; V87-K121 HydrophobicContact CG2-CG 3.64Å; K117-K121 WeakPolarHBondContact O-CG 3.48Å; K117-K121 PolarHBondContact O-N 3.02Å; C118-K121 PolarHBondContact O-N 3.07Å; M119-K121 VanDerWaalsContact C-N 3.3Å; M119-K121 PolarHBondContact O-N 2.87Å; K121-E124 WeakPolarHBondContact CD-OE2 3.4Å; K121-E124 IonicContact NZ-OE1 2.67Å; K121-E124 PolarHBondContact NZ-OE1 3.38Å; K121-E124 IonicContact NZ-OE2 3.13Å; K121-E124 PolarHBondContact NZ-OE2 3.45Å; K121-Y125 VanDerWaalsContact O-CD2 3.22Å; K121-Y125 WeakPolarHBondContact O-CD2 3.46Å; K121-Y125 PolarHBondContact O-N 2.87Å
122L95.1Very high92.7Very high0 Ų058.5 Ų58.50%029%0.294CS..Hα-helixtrans-65.3-41.8174.5-73.2166.1000111.1L74 A78 L86 L90 P96 P106 L107 A110 C118 M119 Y125 N126 A127L74-L122 HydrophobicContact CD2-CD2 4.46Å; A78-L122 HydrophobicContact CB-CD1 4.25Å; L86-L122 HydrophobicContact CD1-CD1 4.24Å; L86-L122 HydrophobicContact CD1-CD2 4.25Å; L86-L122 HydrophobicContact CD1-CG 4.14Å; L86-L122 HydrophobicContact CD2-CD2 4.42Å; L86-L122 HydrophobicContact CD2-CG 4.26Å; L90-L122 HydrophobicContact CD1-CD2 4.27Å; L90-L122 HydrophobicContact CD2-CD2 4.39Å; P96-L122 HydrophobicContact CB-CD2 4.07Å; P106-L122 HydrophobicContact CB-CD1 4.1Å; P106-L122 HydrophobicContact CB-CD2 4.08Å; L107-L122 HydrophobicContact CB-CD1 4.37Å; L107-L122 HydrophobicContact CD1-CB 4.29Å; L107-L122 HydrophobicContact CD1-CD1 4.37Å; A110-L122 HydrophobicContact CB-CD1 4.09Å; C118-L122 WeakPolarHBondContact O-CB 3.41Å; C118-L122 VanDerWaalsContact O-CG 3.27Å; C118-L122 WeakPolarHBondContact O-CG 3.33Å; C118-L122 PolarHBondContact O-N 3.19Å; M119-L122 PolarHBondContact O-N 3.12Å; M119-L122 VanDerWaalsContact O-N 3.13Å; L122-Y125 CarbonylContact O-C 3.56Å; L122-Y125 PolarHBondContact O-N 3.35Å; L122-N126 PolarHBondContact O-N 2.96Å; L122-A127 HydrophobicContact CB-CB 3.94Å; L122-A127 WeakPolarHBondContact O-CB 3.33Å; L122-A127 PolarHBondContact O-N 2.93Å
123L92.6Very high92.8Very high26 Ų2653.1 Ų53.114%0.13628%0.275CS..Hα-helixtrans-66.1-41.1176.7-65.6170.4000112.3L107 M119 G120 Y125 N126 V129 L155L107-L123 HydrophobicContact CD2-CD2 4.32Å; M119-L123 WeakPolarHBondContact O-CG 3.44Å; M119-L123 PolarHBondContact O-N 2.9Å; G120-L123 PolarHBondContact O-N 3.33Å; L123-Y125 PolarHBondContact O-N 3Å; L123-N126 PolarHBondContact O-N 3.02Å; L123-V129 HydrophobicContact CD2-CG1 3.5Å; L123-V129 VanDerWaalsContact CD2-CG1 3.5Å; L123-L155 HydrophobicContact CD1-CD1 4.11Å; L123-L155 HydrophobicContact CD2-CD1 4Å
124E93.1Very high93Very high119 Ų11956 Ų5656%0.55629%0.29SS*.Hα-helixtrans-57.4-28.8172.7-77.5175.4-154.500112.9G120 K121G120-E124 WeakPolarHBondContact O-CG 3.31Å; G120-E124 PolarHBondContact O-N 3.48Å; K121-E124 WeakPolarHBondContact CD-OE2 3.4Å; K121-E124 IonicContact NZ-OE1 2.67Å; K121-E124 PolarHBondContact NZ-OE1 3.38Å; K121-E124 IonicContact NZ-OE2 3.13Å; K121-E124 PolarHBondContact NZ-OE2 3.45Å
125Y93.9Very high93Very high82 Ų8260.6 Ų60.632%0.32231%0.306SS..THydrogen-bonded Turntrans-99.426.2178.4-77-105.7000112.6L90 K91 P96 K121 L122 L123 A127L90-Y125 HydrophobicContact CB-CD1 3.71Å; L90-Y125 HydrophobicContact CB-CE1 3.87Å; L90-Y125 HydrophobicContact CB-CG 4.06Å; L90-Y125 HydrophobicContact CD1-CD1 4.4Å; L90-Y125 HydrophobicContact CD1-CD2 3.95Å; L90-Y125 HydrophobicContact CD1-CG 3.88Å; L90-Y125 HydrophobicContact CG-CD1 4.48Å; L90-Y125 HydrophobicContact CG-CG 4.39Å; K91-Y125 WeakPolarHBondContact CE-OH 3.44Å; K91-Y125 HydrophobicContact CG-CE1 4.33Å; K91-Y125 WeakPolarHBondContact CG-OH 3.42Å; P96-Y125 WeakPolarHBondContact CG-O 3.39Å; K121-Y125 VanDerWaalsContact O-CD2 3.22Å; K121-Y125 WeakPolarHBondContact O-CD2 3.46Å; K121-Y125 PolarHBondContact O-N 2.87Å; L122-Y125 CarbonylContact O-C 3.56Å; L122-Y125 PolarHBondContact O-N 3.35Å; L123-Y125 PolarHBondContact O-N 3Å; Y125-A127 PolarHBondContact O-N 3.24Å
126N90.3Very high92.9Very high138 Ų13858.7 Ų58.774%0.73830%0.302SS*.THydrogen-bonded Turntrans61.238.2175.3-56.9-24000114.5L122 L123 D128L122-N126 PolarHBondContact O-N 2.96Å; L123-N126 PolarHBondContact O-N 3.02Å; N126-D128 PolarHBondContact O-N 3.5Å
127A93.5Very high92.9Very high9 Ų955.3 Ų55.37%0.07429%0.288CS..  trans-60.6128.3164.700000110.2P96 N97 L107 L122 Y125 V129P96-A127 HydrophobicContact CB-CB 3.98Å; N97-A127 WeakPolarHBondContact OD1-CA 3.37Å; L107-A127 HydrophobicContact CD2-CB 4.26Å; L122-A127 HydrophobicContact CB-CB 3.94Å; L122-A127 WeakPolarHBondContact O-CB 3.33Å; L122-A127 PolarHBondContact O-N 2.93Å; Y125-A127 PolarHBondContact O-N 3.24Å; A127-V129 PolarHBondContact O-N 2.92Å
128D92Very high92.9Very high69 Ų6948 Ų4837%0.36926%0.256SS..  trans-81.3119.1178.2-174.5-3.5000109.9N97 N126 N130 I131N97-D128 PolarHBondContact OD1-N 3.27Å; N126-D128 PolarHBondContact O-N 3.5Å; D128-N130 VanDerWaalsContact C-N 3.27Å; D128-N130 PolarHBondContact O-N 3.08Å; D128-N130 WeakPolarHBondContact OD1-CB 3.43Å; D128-N130 PolarHBondContact OD1-N 3.19Å; D128-N130 PolarHBondContact OD1-ND2 3.06Å; D128-N130 VanDerWaalsContact OD1-ND2 3.1Å; D128-I131 HydrophobicContact CB-CD1 3.86Å; D128-I131 HydrophobicContact CB-CG1 3.94Å
129V91.2Very high92.8Very high11 Ų1148 Ų487%0.06726%0.257CS..THydrogen-bonded Turntrans-75.6-15.8-178.3-57.40000113.1L107 L123 A127 L155 H158 V159L107-V129 HydrophobicContact CD2-CB 4.49Å; L107-V129 HydrophobicContact CD2-CG1 4Å; L123-V129 HydrophobicContact CD2-CG1 3.5Å; L123-V129 VanDerWaalsContact CD2-CG1 3.5Å; A127-V129 PolarHBondContact O-N 2.92Å; V129-L155 HydrophobicContact CB-CD1 4.28Å; V129-L155 HydrophobicContact CG1-CD1 3.57Å; V129-L155 HydrophobicContact CG1-CG 4.41Å; V129-H158 HydrophobicContact CG1-CB 4.35Å; V129-H158 WeakPolarHBondContact CG2-O 3.35Å; V129-V159 HydrophobicContact CB-CG2 4.1Å; V129-V159 HydrophobicContact CG2-CB 4.46Å; V129-V159 HydrophobicContact CG2-CG2 3.67Å
130N89.2Confident92.8Very high70 Ų7048 Ų4837%0.37426%0.256SS..THydrogen-bonded Turntrans-94-6.3-174.3-54.7-68.3000113.6D128 C132D128-N130 VanDerWaalsContact C-N 3.27Å; D128-N130 PolarHBondContact O-N 3.08Å; D128-N130 WeakPolarHBondContact OD1-CB 3.43Å; D128-N130 PolarHBondContact OD1-N 3.19Å; D128-N130 PolarHBondContact OD1-ND2 3.06Å; D128-N130 VanDerWaalsContact OD1-ND2 3.1Å; N130-C132 PolarHBondContact O-N 2.88Å
131I92.6Very high92.9Very high28 Ų2846.6 Ų46.614%0.14424%0.242CC..  trans-62.6127176.2-64.7173.4000108.5N97 Q99 T105 H108 D128N97-I131 HydrophobicContact CB-CD1 3.54Å; Q99-I131 HydrophobicContact CG-CG2 4.07Å; Q99-I131 VanDerWaalsContact NE2-CG2 3.35Å; T105-I131 HydrophobicContact CG2-CB 4.12Å; T105-I131 HydrophobicContact CG2-CD1 4.04Å; T105-I131 HydrophobicContact CG2-CG2 3.64Å; H108-I131 PolarHBondContact CE1-O 2.92Å; H108-I131 PolarHBondContact NE2-O 3.1Å; H108-I131 VanDerWaalsContact NE2-O 3.08Å; D128-I131 HydrophobicContact CB-CD1 3.86Å; D128-I131 HydrophobicContact CB-CG1 3.94Å
132C92.8Very high92.8Very high63 Ų6345.2 Ų45.243%0.42624%0.235SC..  trans-98147.5173.655.30000111.2Q99 N130 L137 T138Q99-C132 PolarHBondContact NE2-O 2.93Å; N130-C132 PolarHBondContact O-N 2.88Å; C132-L137 WeakPolarHBondContact CA-O 3.43Å; C132-T138 HydrophobicContact CB-CG2 4.23Å
133N93.8Very high92.8Very high10 Ų1045.2 Ų45.25%0.05324%0.235CC..  trans-75.9-178.4167.281.5-12.4000110.8S102 G103 E135 G136 L137S102-N133 WeakPolarHBondContact O-CB 3.43Å; G103-N133 WeakPolarHBondContact O-CA 3.27Å; N133-E135 PolarHBondContact O-N 3.36Å; N133-E135 WeakPolarHBondContact OD1-CA 3.44Å; N133-E135 WeakPolarHBondContact OD1-CB 3.4Å; N133-E135 PolarHBondContact OD1-N 3.17Å; N133-G136 PolarHBondContact O-N 3.18Å; N133-G136 PolarHBondContact OD1-N 2.92Å; N133-L137 PolarHBondContact N-O 3.39Å; N133-L137 WeakPolarHBondContact OD1-CB 3.48Å; N133-L137 PolarHBondContact OD1-N 3.14Å; N133-L137 PolarHBondContact OD1-O 3.1Å
134N92.6Very high92.9Very high122 Ų12244 Ų4465%0.65223%0.229SC*.THydrogen-bonded Turntrans-64.6-12.7-178.8-64-7.2000113.9I101 S102I101-N134 PolarHBondContact O-ND2 3.42Å; S102-N134 VanDerWaalsContact C-CG 3.45Å; S102-N134 WeakPolarHBondContact O-CB 3.3Å; S102-N134 VanDerWaalsContact O-CG 3.25Å; S102-N134 PolarHBondContact O-N 3.47Å; S102-N134 PolarHBondContact O-OD1 3.33Å
135E92Very high92.9Very high117 Ų11740.9 Ų40.955%0.54722%0.217SC..THydrogen-bonded Turntrans-98.75.1175.7-61.3172.5162.900112N133 L137 A167N133-E135 PolarHBondContact O-N 3.36Å; N133-E135 WeakPolarHBondContact OD1-CA 3.44Å; N133-E135 WeakPolarHBondContact OD1-CB 3.4Å; N133-E135 PolarHBondContact OD1-N 3.17Å; E135-L137 HydrophobicContact CB-CD1 4.3Å; E135-L137 HydrophobicContact CB-CG 4.17Å; E135-L137 PolarHBondContact O-N 3.23Å; E135-L137 WeakPolarHBondContact OE2-CD1 3.31Å; E135-A167 VanDerWaalsContact O-CB 3.26Å; E135-A167 WeakPolarHBondContact O-CB 3.37Å; E135-A167 PolarHBondContact O-N 3Å
136G91.9Very high92.7Very high15 Ų1540 Ų4016%0.15522%0.219CC..SBendtrans79.50.7-175.800000114.2N133N133-G136 PolarHBondContact O-N 3.18Å; N133-G136 PolarHBondContact OD1-N 2.92Å
137L93.4Very high92.8Very high25 Ų2534.4 Ų34.413%0.13119%0.193CC..  trans-76.6130.7-178.1-58.1172.2000111.1H108 C132 N133 E135 H141 W142 D166H108-L137 PolarHBondContact NE2-O 2.91Å; C132-L137 WeakPolarHBondContact CA-O 3.43Å; N133-L137 PolarHBondContact N-O 3.39Å; N133-L137 WeakPolarHBondContact OD1-CB 3.48Å; N133-L137 PolarHBondContact OD1-N 3.14Å; N133-L137 PolarHBondContact OD1-O 3.1Å; E135-L137 HydrophobicContact CB-CD1 4.3Å; E135-L137 HydrophobicContact CB-CG 4.17Å; E135-L137 PolarHBondContact O-N 3.23Å; E135-L137 WeakPolarHBondContact OE2-CD1 3.31Å; L137-H141 HydrophobicContact CB-CB 4.26Å; L137-H141 HydrophobicContact CD2-CB 3.82Å; L137-W142 HydrophobicContact CD1-CZ2 4Å; L137-D166 HydrophobicContact CD2-CB 3.76Å
138T93.7Very high92.8Very high3 Ų339.5 Ų39.52%0.01821%0.211CC..  trans-101.8174.5171.1600000111.7H108 C132 I140 H141 W142 V164H108-T138 WeakPolarHBondContact NE2-CA 3.4Å; C132-T138 HydrophobicContact CB-CG2 4.23Å; T138-I140 PolarHBondContact O-N 3.48Å; T138-I140 VanDerWaalsContact O-N 3.17Å; T138-I140 VanDerWaalsContact OG1-CG2 3.22Å; T138-I140 WeakPolarHBondContact OG1-CG2 3.49Å; T138-H141 PolarHBondContact N-ND1 2.92Å; T138-H141 WeakPolarHBondContact O-CB 3.49Å; T138-H141 PolarHBondContact O-N 3.17Å; T138-H141 VanDerWaalsContact O-N 3.08Å; T138-H141 PolarHBondContact OG1-ND1 2.95Å; T138-W142 VanDerWaalsContact O-CD1 3.32Å; T138-V164 HydrophobicContact CG2-CB 4.43Å; T138-V164 HydrophobicContact CG2-CG1 3.76Å
139A93.4Very high92.8Very high1 Ų137.6 Ų37.61%0.00820%0.201CC..Hα-helixtrans-55.3-33.9177.200000113.2L107 A111 H141 W142 L143 L155L107-A139 HydrophobicContact CD2-CB 4.14Å; L107-A139 HydrophobicContact CG-CB 4.05Å; A111-A139 HydrophobicContact CB-CB 4.27Å; A139-H141 VanDerWaalsContact C-N 3.3Å; A139-H141 PolarHBondContact O-N 3.42Å; A139-W142 PolarHBondContact O-N 2.93Å; A139-L143 WeakPolarHBondContact O-CG 3.38Å; A139-L143 PolarHBondContact O-N 3.23Å; A139-L155 HydrophobicContact CB-CD2 3.82Å
140I94.4Very high92.8Very high4 Ų443.4 Ų43.42%0.02123%0.228CC..Hα-helixtrans-63.9-34.2179.1-154.4178.3000112.4T138 L143 A144 L152 L155 V156 V162 A172 L188T138-I140 PolarHBondContact O-N 3.48Å; T138-I140 VanDerWaalsContact O-N 3.17Å; T138-I140 VanDerWaalsContact OG1-CG2 3.22Å; T138-I140 WeakPolarHBondContact OG1-CG2 3.49Å; I140-L143 PolarHBondContact O-N 3.22Å; I140-A144 WeakPolarHBondContact O-CB 3.41Å; I140-A144 PolarHBondContact O-N 3.05Å; I140-L152 HydrophobicContact CD1-CD1 3.9Å; I140-L152 HydrophobicContact CG1-CD1 3.29Å; I140-L155 HydrophobicContact CB-CD2 4.36Å; I140-V156 HydrophobicContact CD1-CG2 4.03Å; I140-V162 HydrophobicContact CD1-CB 4.15Å; I140-V162 HydrophobicContact CD1-CG1 4.12Å; I140-A172 HydrophobicContact CB-CB 4.45Å; I140-A172 HydrophobicContact CD1-CB 4.46Å; I140-A172 HydrophobicContact CG1-CB 4.12Å; I140-A172 HydrophobicContact CG2-CB 3.86Å; I140-L188 HydrophobicContact CD1-CD2 3.81Å; I140-L188 HydrophobicContact CG1-CD2 4.26Å
141H94.6Very high92.9Very high1 Ų140.7 Ų40.71%0.00521%0.213CC..Hα-helixtrans-66.1-45.9176.1-68.287.8000111.1L137 T138 A139 L143 A144 V145 V164 Q170 A172L137-H141 HydrophobicContact CB-CB 4.26Å; L137-H141 HydrophobicContact CD2-CB 3.82Å; T138-H141 PolarHBondContact N-ND1 2.92Å; T138-H141 WeakPolarHBondContact O-CB 3.49Å; T138-H141 PolarHBondContact O-N 3.17Å; T138-H141 VanDerWaalsContact O-N 3.08Å; T138-H141 PolarHBondContact OG1-ND1 2.95Å; A139-H141 VanDerWaalsContact C-N 3.3Å; A139-H141 PolarHBondContact O-N 3.42Å; H141-L143 VanDerWaalsContact C-N 3.28Å; H141-L143 PolarHBondContact O-N 3.46Å; H141-A144 WeakPolarHBondContact O-CA 3.4Å; H141-A144 WeakPolarHBondContact O-CB 3.41Å; H141-A144 PolarHBondContact O-N 3.09Å; H141-V145 WeakPolarHBondContact O-CG2 3.43Å; H141-V145 PolarHBondContact O-N 3.3Å; H141-V164 PolarHBondContact CE1-O 3.22Å; H141-V164 PolarHBondContact NE2-O 3.31Å; H141-Q170 PolarHBondContact NE2-O 3.36Å; H141-A172 PolarHBondContact NE2-N 3.1Å
142W93.3Very high92.9Very high37 Ų3739.3 Ų39.314%0.1421%0.206CC..Hα-helixtrans-63.4-32.8178.5-68.4100.8000113.4H108 A111 R112 L137 T138 A139 N146H108-W142 AromaticContact CD2-CD1 3.62Å; H108-W142 AromaticContact CD2-NE1 3.62Å; A111-W142 HydrophobicContact CB-CB 4.17Å; R112-W142 HydrophobicContact CB-CB 4.32Å; R112-W142 HydrophobicContact CB-CD2 4.15Å; R112-W142 HydrophobicContact CB-CE3 3.9Å; R112-W142 HydrophobicContact CB-CG 4.35Å; R112-W142 HydrophobicContact CG-CD2 4.43Å; R112-W142 HydrophobicContact CG-CE3 3.71Å; R112-W142 HydrophobicContact CG-CZ3 4.06Å; L137-W142 HydrophobicContact CD1-CZ2 4Å; T138-W142 VanDerWaalsContact O-CD1 3.32Å; A139-W142 PolarHBondContact O-N 2.93Å; W142-N146 PolarHBondContact O-ND2 3.29Å
143L94.2Very high92.8Very high0 Ų041.4 Ų41.40%021%0.21CC..Hα-helixtrans-69.3-40.4172.6-63.7176.2000111.4A111 M119 A139 I140 H141 N146 G147 R148 L151 L152 L155A111-L143 HydrophobicContact CB-CD2 3.78Å; A111-L143 HydrophobicContact CB-CG 3.99Å; M119-L143 HydrophobicContact CE-CD1 4.02Å; M119-L143 HydrophobicContact CE-CD2 4.16Å; M119-L143 HydrophobicContact SD-CD2 4.24Å; A139-L143 WeakPolarHBondContact O-CG 3.38Å; A139-L143 PolarHBondContact O-N 3.23Å; I140-L143 PolarHBondContact O-N 3.22Å; H141-L143 VanDerWaalsContact C-N 3.28Å; H141-L143 PolarHBondContact O-N 3.46Å; L143-N146 PolarHBondContact O-N 3.48Å; L143-G147 PolarHBondContact O-N 3.01Å; L143-R148 HydrophobicContact CB-CB 4.44Å; L143-R148 HydrophobicContact CD2-CB 3.81Å; L143-R148 HydrophobicContact CD2-CG 4.42Å; L143-R148 PolarHBondContact O-N 3.17Å; L143-L151 HydrophobicContact CD1-CB 4.32Å; L143-L151 HydrophobicContact CD2-CB 3.7Å; L143-L151 HydrophobicContact CD2-CD1 4.12Å; L143-L152 HydrophobicContact CB-CB 4.39Å; L143-L152 HydrophobicContact CB-CD1 4.45Å; L143-L152 HydrophobicContact CD1-CB 4.21Å; L143-L152 HydrophobicContact CD1-CD1 4.28Å; L143-L155 HydrophobicContact CD1-CB 4.04Å; L143-L155 HydrophobicContact CD1-CD2 3.58Å; L143-L155 HydrophobicContact CD1-CG 4.43Å
144A94.6Very high92.5Very high0 Ų044.1 Ų44.10%022%0.224CC..Hα-helixtrans-66.4-41.417700000113I140 H141 N146 G147 A172 V175 A176 H181 T184I140-A144 WeakPolarHBondContact O-CB 3.41Å; I140-A144 PolarHBondContact O-N 3.05Å; H141-A144 WeakPolarHBondContact O-CA 3.4Å; H141-A144 WeakPolarHBondContact O-CB 3.41Å; H141-A144 PolarHBondContact O-N 3.09Å; A144-N146 PolarHBondContact O-N 2.95Å; A144-G147 PolarHBondContact O-N 3.42Å; A144-A172 HydrophobicContact CB-CB 3.89Å; A144-A172 VanDerWaalsContact CB-O 3.3Å; A144-A172 WeakPolarHBondContact CB-O 3.23Å; A144-V175 HydrophobicContact CB-CB 4.25Å; A144-V175 HydrophobicContact CB-CG1 4.21Å; A144-A176 HydrophobicContact CB-CB 4.2Å; A144-H181 PolarHBondContact O-CD2 2.85Å; A144-T184 HydrophobicContact CB-CG2 4.32Å
145V93.4Very high92.4Very high53 Ų5338.3 Ų38.332%0.32119%0.193SC..Hα-helixtrans-54.3-43.5174.9171.90000111.3H141 V175 H181H141-V145 WeakPolarHBondContact O-CG2 3.43Å; H141-V145 PolarHBondContact O-N 3.3Å; V145-V175 HydrophobicContact CB-CG1 4.14Å; V145-V175 HydrophobicContact CG2-CG1 3.39Å; V145-H181 PolarHBondContact O-NE2 2.89Å
146N90.1Very high92.2Very high65 Ų6533.6 Ų33.635%0.34817%0.172SC..THydrogen-bonded Turntrans-98.64.4-172.2-65-65.5000114.2R112 W142 L143 A144 R148R112-N146 PolarHBondContact O-ND2 2.9Å; W142-N146 PolarHBondContact O-ND2 3.29Å; L143-N146 PolarHBondContact O-N 3.48Å; A144-N146 PolarHBondContact O-N 2.95Å; N146-R148 VanDerWaalsContact C-N 3.29Å; N146-R148 HydrophobicContact CB-CG 3.82Å; N146-R148 PolarHBondContact O-N 3.27Å
147G92.6Very high91.9Very high20 Ų2039.6 Ų39.621%0.20620%0.196CC..THydrogen-bonded Turntrans62.731.1179.500000114.4L143 A144 T149 H181 T184L143-G147 PolarHBondContact O-N 3.01Å; A144-G147 PolarHBondContact O-N 3.42Å; G147-T149 PolarHBondContact O-N 3.07Å; G147-H181 VanDerWaalsContact CA-CD2 3.48Å; G147-H181 WeakPolarHBondContact CA-CD2 3.39Å; G147-H181 PolarHBondContact N-CD2 3.08Å; G147-H181 VanDerWaalsContact N-CD2 3.33Å; G147-H181 PolarHBondContact N-NE2 3.39Å; G147-T184 WeakPolarHBondContact CA-OG1 3.43Å
148R93Very high91.4Very high116 Ų11643.9 Ų43.944%0.43822%0.215SC..  trans-82.461.1-173.6-61.9-65.8-171.5-177.5-0.5111.8L143 N146 E150 L151 L152L143-R148 HydrophobicContact CB-CB 4.44Å; L143-R148 HydrophobicContact CD2-CB 3.81Å; L143-R148 HydrophobicContact CD2-CG 4.42Å; L143-R148 PolarHBondContact O-N 3.17Å; N146-R148 VanDerWaalsContact C-N 3.29Å; N146-R148 HydrophobicContact CB-CG 3.82Å; N146-R148 PolarHBondContact O-N 3.27Å; R148-E150 PolarHBondContact O-N 2.95Å; R148-L151 HydrophobicContact CB-CB 4.29Å; R148-L151 HydrophobicContact CB-CD1 4.14Å; R148-L151 HydrophobicContact CB-CG 4.38Å; R148-L151 HydrophobicContact CG-CD1 4.48Å; R148-L151 PolarHBondContact O-N 3.43Å; R148-L151 VanDerWaalsContact O-N 3.09Å; R148-L152 PolarHBondContact O-N 2.86Å
149T92.2Very high91Very high29 Ų2944.9 Ų44.918%0.17822%0.221CC..Hα-helixtrans-57-39.1-169.8-51.40000114.5G147 L151 L152 H153 T183 T184 C187G147-T149 PolarHBondContact O-N 3.07Å; T149-L151 PolarHBondContact O-N 2.87Å; T149-L152 WeakPolarHBondContact O-CB 3.06Å; T149-L152 PolarHBondContact O-N 3.29Å; T149-H153 PolarHBondContact O-N 3.33Å; T149-T183 WeakPolarHBondContact CG2-O 3.42Å; T149-T183 PolarHBondContact OG1-OG1 2.97Å; T149-T184 PolarHBondContact OG1-N 3.4Å; T149-T184 VanDerWaalsContact OG1-N 3.17Å; T149-T184 PolarHBondContact OG1-OG1 3.27Å; T149-C187 HydrophobicContact CG2-CB 3.87Å
150E90.4Very high90.2Very high133 Ų13350.4 Ų50.462%0.62126%0.26SS*.Hα-helixtrans-61.8-44.1177.1-69.1-173.9-164.900112.3K116 R148 L152 H153 D154K116-E150 IonicContact NZ-OE2 3.19Å; K116-E150 PolarHBondContact NZ-OE2 3.01Å; R148-E150 PolarHBondContact O-N 2.95Å; E150-L152 VanDerWaalsContact C-N 3.29Å; E150-H153 WeakPolarHBondContact O-CB 3.22Å; E150-H153 PolarHBondContact O-N 3.33Å; E150-D154 PolarHBondContact O-N 3.04Å
151L91.8Very high89.8Confident12 Ų1254 Ų546%0.06328%0.279CS..Hα-helixtrans-70.7-32.9179.5-58.2-176.5000111.3K116 M119 L143 R148 T149 H153 D154 L155K116-L151 HydrophobicContact CB-CD2 3.49Å; K116-L151 VanDerWaalsContact CB-CD2 3.49Å; K116-L151 HydrophobicContact CD-CD2 3.79Å; K116-L151 HydrophobicContact CG-CD2 3.38Å; M119-L151 HydrophobicContact CE-CB 4.31Å; M119-L151 HydrophobicContact SD-CB 4.2Å; M119-L151 HydrophobicContact SD-CD1 3.86Å; M119-L151 HydrophobicContact SD-CD2 4.47Å; M119-L151 HydrophobicContact SD-CG 4.41Å; L143-L151 HydrophobicContact CD1-CB 4.32Å; L143-L151 HydrophobicContact CD2-CB 3.7Å; L143-L151 HydrophobicContact CD2-CD1 4.12Å; R148-L151 HydrophobicContact CB-CB 4.29Å; R148-L151 HydrophobicContact CB-CD1 4.14Å; R148-L151 HydrophobicContact CB-CG 4.38Å; R148-L151 HydrophobicContact CG-CD1 4.48Å; R148-L151 PolarHBondContact O-N 3.43Å; R148-L151 VanDerWaalsContact O-N 3.09Å; T149-L151 PolarHBondContact O-N 2.87Å; L151-H153 VanDerWaalsContact C-N 3.35Å; L151-D154 PolarHBondContact O-N 3.32Å; L151-L155 VanDerWaalsContact O-CB 3.31Å; L151-L155 WeakPolarHBondContact O-CB 3.38Å; L151-L155 PolarHBondContact O-N 2.94Å
152L92.6Very high89.7Confident0 Ų054.5 Ų54.50%028%0.282CS..Hα-helixtrans-63.2-44.8173.2178.567.7000110.4I140 L143 R148 T149 E150 D154 L155 V156 T184 C187 L188I140-L152 HydrophobicContact CD1-CD1 3.9Å; I140-L152 HydrophobicContact CG1-CD1 3.29Å; L143-L152 HydrophobicContact CB-CB 4.39Å; L143-L152 HydrophobicContact CB-CD1 4.45Å; L143-L152 HydrophobicContact CD1-CB 4.21Å; L143-L152 HydrophobicContact CD1-CD1 4.28Å; R148-L152 PolarHBondContact O-N 2.86Å; T149-L152 WeakPolarHBondContact O-CB 3.06Å; T149-L152 PolarHBondContact O-N 3.29Å; E150-L152 VanDerWaalsContact C-N 3.29Å; L152-D154 VanDerWaalsContact C-N 3.32Å; L152-D154 PolarHBondContact O-N 3.42Å; L152-L155 PolarHBondContact O-N 3.25Å; L152-V156 HydrophobicContact CD1-CG2 3.65Å; L152-V156 HydrophobicContact CG-CG2 3.98Å; L152-V156 WeakPolarHBondContact O-CB 3.46Å; L152-V156 WeakPolarHBondContact O-CG2 3.46Å; L152-V156 PolarHBondContact O-N 2.97Å; L152-T184 HydrophobicContact CD2-CG2 3.49Å; L152-T184 VanDerWaalsContact CD2-CG2 3.49Å; L152-C187 HydrophobicContact CD2-CB 4.03Å; L152-L188 HydrophobicContact CD1-CD2 4.01Å; L152-L188 HydrophobicContact CD2-CD1 4.5Å; L152-L188 HydrophobicContact CD2-CD2 3.77Å; L152-L188 HydrophobicContact CD2-CG 3.76Å; L152-L188 HydrophobicContact CG-CD2 4.4Å
153H90.1Very high89.7Confident107 Ų10753.7 Ų53.750%0.49528%0.281SS..Hα-helixtrans-59.3-43.7177.5-168.367.4000112T149 E150 L151T149-H153 PolarHBondContact O-N 3.33Å; E150-H153 WeakPolarHBondContact O-CB 3.22Å; E150-H153 PolarHBondContact O-N 3.33Å; L151-H153 VanDerWaalsContact C-N 3.35Å
154D87.9Confident89.6Confident66 Ų6655.3 Ų55.335%0.35329%0.29SS..Hα-helixtrans-64.4-44.3175.6-65.6-21.4000111.5K116 E150 L151 L152 H158K116-D154 WeakPolarHBondContact CE-OD2 3.44Å; E150-D154 PolarHBondContact O-N 3.04Å; L151-D154 PolarHBondContact O-N 3.32Å; L152-D154 VanDerWaalsContact C-N 3.32Å; L152-D154 PolarHBondContact O-N 3.42Å; D154-H158 PolarHBondContact O-CD2 2.82Å
155L89.6Confident89.6Confident1 Ų159.2 Ų59.21%0.00531%0.309CS..Hα-helixtrans-68.5-40.7-177.5-171.373.5000112.2L107 M119 L123 V129 A139 I140 L143 L151 L152 Q157 H158 V159L107-L155 HydrophobicContact CD2-CD1 4.37Å; M119-L155 HydrophobicContact CE-CD1 4.29Å; L123-L155 HydrophobicContact CD1-CD1 4.11Å; L123-L155 HydrophobicContact CD2-CD1 4Å; V129-L155 HydrophobicContact CB-CD1 4.28Å; V129-L155 HydrophobicContact CG1-CD1 3.57Å; V129-L155 HydrophobicContact CG1-CG 4.41Å; A139-L155 HydrophobicContact CB-CD2 3.82Å; I140-L155 HydrophobicContact CB-CD2 4.36Å; L143-L155 HydrophobicContact CD1-CB 4.04Å; L143-L155 HydrophobicContact CD1-CD2 3.58Å; L143-L155 HydrophobicContact CD1-CG 4.43Å; L151-L155 VanDerWaalsContact O-CB 3.31Å; L151-L155 WeakPolarHBondContact O-CB 3.38Å; L151-L155 PolarHBondContact O-N 2.94Å; L152-L155 PolarHBondContact O-N 3.25Å; L155-Q157 PolarHBondContact O-N 2.99Å; L155-H158 WeakPolarHBondContact O-CA 3.13Å; L155-H158 WeakPolarHBondContact O-CB 3.37Å; L155-H158 PolarHBondContact O-N 2.91Å; L155-V159 HydrophobicContact CG-CG2 4.23Å; L155-V159 WeakPolarHBondContact O-CG2 3.48Å; L155-V159 PolarHBondContact O-N 3.03Å
156V88.9Confident89.6Confident18 Ų1858 Ų5811%0.10930%0.3CS..Hα-helixtrans-65.1-25-174.2170.80000112.4I140 L152 H158 V159 V162 S191I140-V156 HydrophobicContact CD1-CG2 4.03Å; L152-V156 HydrophobicContact CD1-CG2 3.65Å; L152-V156 HydrophobicContact CG-CG2 3.98Å; L152-V156 WeakPolarHBondContact O-CB 3.46Å; L152-V156 WeakPolarHBondContact O-CG2 3.46Å; L152-V156 PolarHBondContact O-N 2.97Å; V156-H158 PolarHBondContact O-N 3.3Å; V156-H158 VanDerWaalsContact O-N 3.14Å; V156-V159 PolarHBondContact O-N 2.87Å; V156-V159 VanDerWaalsContact O-N 3.1Å; V156-V162 HydrophobicContact CG1-CG1 3.94Å; V156-V162 HydrophobicContact CG2-CG1 4.35Å; V156-S191 VanDerWaalsContact CG1-CB 3.47Å; V156-S191 WeakPolarHBondContact CG1-OG 3.5Å
157Q85.5Confident89.7Confident140 Ų14058 Ų5865%0.65431%0.31SS*.THydrogen-bonded Turntrans-60.7-21.2170.9-64.51807.100113.2L155L155-Q157 PolarHBondContact O-N 2.99Å
158H83.4Confident89.7Confident116 Ų11662.7 Ų62.754%0.53733%0.328SS..THydrogen-bonded Turntrans-105.91.5179-60.6-74.5000113.3V129 D154 L155 V156V129-H158 HydrophobicContact CG1-CB 4.35Å; V129-H158 WeakPolarHBondContact CG2-O 3.35Å; D154-H158 PolarHBondContact O-CD2 2.82Å; L155-H158 WeakPolarHBondContact O-CA 3.13Å; L155-H158 WeakPolarHBondContact O-CB 3.37Å; L155-H158 PolarHBondContact O-N 2.91Å; V156-H158 PolarHBondContact O-N 3.3Å; V156-H158 VanDerWaalsContact O-N 3.14Å
159V84.2Confident89.8Confident24 Ų2457.4 Ų57.415%0.14531%0.309CS..  trans-104.8127.1-177.81750000109.6V129 L155 V156 N161 V162V129-V159 HydrophobicContact CB-CG2 4.1Å; V129-V159 HydrophobicContact CG2-CB 4.46Å; V129-V159 HydrophobicContact CG2-CG2 3.67Å; L155-V159 HydrophobicContact CG-CG2 4.23Å; L155-V159 WeakPolarHBondContact O-CG2 3.48Å; L155-V159 PolarHBondContact O-N 3.03Å; V156-V159 PolarHBondContact O-N 2.87Å; V156-V159 VanDerWaalsContact O-N 3.1Å; V159-N161 WeakPolarHBondContact CG1-O 3.41Å; V159-V162 HydrophobicContact CG1-CG1 4.24Å
160S76.9Confident89.9Confident116 Ų11657.6 Ų57.681%0.81131%0.307SS*.SBendtrans-85.7-25.5177.953.30000114
161N87Confident90.2Very high81 Ų8151.2 Ų51.243%0.43328%0.278SS..  trans-136.3117.3176.1178.520.7000109.5V159 D163 V164V159-N161 WeakPolarHBondContact CG1-O 3.41Å; N161-D163 PolarHBondContact OD1-N 2.94Å; N161-V164 WeakPolarHBondContact O-CG2 3.45Å
162V91.2Very high90.4Very high11 Ų1150.7 Ų50.77%0.06728%0.275CS..SBendtrans-83.5-18178.4-65.70000113I140 V156 V159 V164 A193I140-V162 HydrophobicContact CD1-CB 4.15Å; I140-V162 HydrophobicContact CD1-CG1 4.12Å; V156-V162 HydrophobicContact CG1-CG1 3.94Å; V156-V162 HydrophobicContact CG2-CG1 4.35Å; V159-V162 HydrophobicContact CG1-CG1 4.24Å; V162-V164 PolarHBondContact O-N 2.87Å; V162-A193 HydrophobicContact CG2-CB 3.76Å
163D93.2Very high90.6Very high20 Ų2050.8 Ų50.811%0.10728%0.275CS..  trans-90.348.6178.1-65.5-40.3000111.2N161 T171 A193 D194N161-D163 PolarHBondContact OD1-N 2.94Å; D163-T171 HydrophobicContact CB-CG2 4.12Å; D163-A193 WeakPolarHBondContact OD1-CA 3.44Å; D163-D194 PolarHBondContact OD1-N 2.81Å; D163-D194 WeakPolarHBondContact OD2-CB 3.26Å; D163-D194 PolarHBondContact OD2-N 3.33Å
164V92.7Very high91Very high34 Ų3445.7 Ų45.721%0.20625%0.252CS..  trans-72.6132.4167.5-174.10000107.9T138 H141 N161 V162 T171T138-V164 HydrophobicContact CG2-CB 4.43Å; T138-V164 HydrophobicContact CG2-CG1 3.76Å; H141-V164 PolarHBondContact CE1-O 3.22Å; H141-V164 PolarHBondContact NE2-O 3.31Å; N161-V164 WeakPolarHBondContact O-CG2 3.45Å; V162-V164 PolarHBondContact O-N 2.87Å; V164-T171 WeakPolarHBondContact O-CA 3.46Å
165E94.2Very high91.4Very high82 Ų8243 Ų4338%0.38324%0.238SC..  trans-100135.7-176.9-69.7172.6-161.300110.2Q170 T171 R197E165-Q170 CarbonylContact C-O 3.53Å; E165-Q170 WeakPolarHBondContact CA-O 3.32Å; E165-T171 HydrophobicContact CG-CG2 4.03Å; E165-R197 IonicContact OE1-CZ 2.78Å; E165-R197 IonicContact OE1-NE 3.56Å; E165-R197 PolarHBondContact OE1-NE 3.03Å; E165-R197 VanDerWaalsContact OE1-NE 3.08Å; E165-R197 IonicContact OE1-NH2 3.73Å; E165-R197 PolarHBondContact OE1-NH2 2.73Å
166D93.7Very high91.7Very high27 Ų2743 Ų4314%0.14424%0.238CC..  trans-76.5-177169.978.1-0.3000112L137 M168 G169 Q170L137-D166 HydrophobicContact CD2-CB 3.76Å; D166-M168 PolarHBondContact O-N 3.44Å; D166-M168 VanDerWaalsContact OD1-CA 3.32Å; D166-M168 WeakPolarHBondContact OD1-CA 3.3Å; D166-M168 WeakPolarHBondContact OD1-CB 3.42Å; D166-M168 PolarHBondContact OD1-N 2.85Å; D166-G169 PolarHBondContact O-N 3.19Å; D166-G169 PolarHBondContact OD1-N 3.1Å; D166-G169 VanDerWaalsContact OD1-N 3.11Å; D166-Q170 PolarHBondContact N-O 3.29Å; D166-Q170 WeakPolarHBondContact OD1-CB 3.44Å; D166-Q170 PolarHBondContact OD1-N 3.18Å
167A92.8Very high92.1Very high66 Ų6642.1 Ų42.155%0.54523%0.232SC..THydrogen-bonded Turntrans-59.7-17.2179.400000114.3E135E135-A167 VanDerWaalsContact O-CB 3.26Å; E135-A167 WeakPolarHBondContact O-CB 3.37Å; E135-A167 PolarHBondContact O-N 3Å
168M93Very high92.6Very high118 Ų11838.1 Ų38.158%0.58121%0.214SC*.THydrogen-bonded Turntrans-102.66.4177.7-59.5-61.9153.400112.6D166 Q170 V200D166-M168 PolarHBondContact O-N 3.44Å; D166-M168 VanDerWaalsContact OD1-CA 3.32Å; D166-M168 WeakPolarHBondContact OD1-CA 3.3Å; D166-M168 WeakPolarHBondContact OD1-CB 3.42Å; D166-M168 PolarHBondContact OD1-N 2.85Å; M168-Q170 VanDerWaalsContact C-N 3.27Å; M168-Q170 HydrophobicContact CB-CG 4.23Å; M168-V200 VanDerWaalsContact C-CG2 3.5Å; M168-V200 WeakPolarHBondContact O-CB 3.44Å; M168-V200 VanDerWaalsContact O-CG2 3.3Å; M168-V200 WeakPolarHBondContact O-CG2 3.28Å; M168-V200 PolarHBondContact O-N 3.36Å
169G94Very high93.2Very high4 Ų435.8 Ų35.84%0.04121%0.205CC..SBendtrans75.313.1-175.700000113.7D166 N199D166-G169 PolarHBondContact O-N 3.19Å; D166-G169 PolarHBondContact OD1-N 3.1Å; D166-G169 VanDerWaalsContact OD1-N 3.11Å; G169-N199 WeakPolarHBondContact O-CA 3.48Å; G169-N199 WeakPolarHBondContact O-CB 3.36Å
170Q95.9Very high93.7Very high33 Ų3335.6 Ų35.615%0.15421%0.208CC..  trans-84.8137.1179.1-58.1-173.330.100110.2H141 E165 D166 M168 H174 N199 F208H141-Q170 PolarHBondContact NE2-O 3.36Å; E165-Q170 CarbonylContact C-O 3.53Å; E165-Q170 WeakPolarHBondContact CA-O 3.32Å; D166-Q170 PolarHBondContact N-O 3.29Å; D166-Q170 WeakPolarHBondContact OD1-CB 3.44Å; D166-Q170 PolarHBondContact OD1-N 3.18Å; M168-Q170 VanDerWaalsContact C-N 3.27Å; M168-Q170 HydrophobicContact CB-CG 4.23Å; Q170-H174 HydrophobicContact CB-CB 4.09Å; Q170-N199 HydrophobicContact CG-CB 4.16Å; Q170-F208 HydrophobicContact CG-CZ 4.22Å
171T96.4Very high94.6Very high0 Ų032.5 Ų32.50%018%0.181CC..  trans-95166.9171.569.10000110.9D163 V164 E165 L173 H174 V175 R197D163-T171 HydrophobicContact CB-CG2 4.12Å; V164-T171 WeakPolarHBondContact O-CA 3.46Å; E165-T171 HydrophobicContact CG-CG2 4.03Å; T171-L173 PolarHBondContact O-N 2.92Å; T171-L173 PolarHBondContact OG1-N 3.35Å; T171-H174 PolarHBondContact N-ND1 3.17Å; T171-H174 WeakPolarHBondContact O-CB 3.4Å; T171-H174 PolarHBondContact O-N 2.94Å; T171-H174 PolarHBondContact OG1-ND1 2.91Å; T171-V175 PolarHBondContact O-N 3.45Å; T171-R197 HydrophobicContact CG2-CG 4.32Å
172A95.6Very high95Very high0 Ų033.2 Ų33.20%018%0.18CC..Hα-helixtrans-55.2-27.3172.300000113.5I140 H141 A144 V175 A176 L188I140-A172 HydrophobicContact CB-CB 4.45Å; I140-A172 HydrophobicContact CD1-CB 4.46Å; I140-A172 HydrophobicContact CG1-CB 4.12Å; I140-A172 HydrophobicContact CG2-CB 3.86Å; H141-A172 PolarHBondContact NE2-N 3.1Å; A144-A172 HydrophobicContact CB-CB 3.89Å; A144-A172 VanDerWaalsContact CB-O 3.3Å; A144-A172 WeakPolarHBondContact CB-O 3.23Å; A172-V175 PolarHBondContact O-N 3.08Å; A172-A176 WeakPolarHBondContact O-CB 3.45Å; A172-A176 PolarHBondContact O-N 3.18Å; A172-L188 HydrophobicContact CB-CD1 4.07Å; A172-L188 HydrophobicContact CB-CD2 4.26Å; A172-L188 WeakPolarHBondContact O-CD1 3.4Å
173L97.4Very high95.3Very high2 Ų236.5 Ų36.51%0.0120%0.2CC..Hα-helixtrans-66.6-42175.3-176.561.2000111.5T171 V175 A176 C177 V185 L188 L189 A193 P205T171-L173 PolarHBondContact O-N 2.92Å; T171-L173 PolarHBondContact OG1-N 3.35Å; L173-V175 VanDerWaalsContact C-N 3.34Å; L173-V175 PolarHBondContact O-N 3.38Å; L173-A176 PolarHBondContact O-N 3.22Å; L173-C177 WeakPolarHBondContact O-CB 3.41Å; L173-C177 PolarHBondContact O-N 3.48Å; L173-C177 PolarHBondContact O-SG 3.49Å; L173-V185 HydrophobicContact CD1-CB 4.41Å; L173-V185 HydrophobicContact CD1-CG1 3.97Å; L173-V185 HydrophobicContact CD1-CG2 4.44Å; L173-L188 HydrophobicContact CB-CD1 4.21Å; L173-L188 HydrophobicContact CD1-CB 4.19Å; L173-L188 HydrophobicContact CD1-CD1 4.33Å; L173-L189 HydrophobicContact CD1-CD2 4.23Å; L173-L189 HydrophobicContact CD1-CG 4.2Å; L173-L189 HydrophobicContact CD2-CD2 3.73Å; L173-A193 HydrophobicContact CB-CB 4.49Å; L173-A193 HydrophobicContact CD2-CB 4.15Å; L173-P205 HydrophobicContact CB-CG 4.49Å; L173-P205 HydrophobicContact CD2-CB 4.1Å; L173-P205 HydrophobicContact CD2-CG 3.76Å; L173-P205 HydrophobicContact CG-CB 3.92Å; L173-P205 HydrophobicContact CG-CG 3.91Å
174H97.4Very high95.4Very high0 Ų035.6 Ų35.60%020%0.195CC..Hα-helixtrans-58.1-48.3174.3-65.785.1000111.2Q170 T171 A176 C177 Q178 R197 A203 F208Q170-H174 HydrophobicContact CB-CB 4.09Å; T171-H174 PolarHBondContact N-ND1 3.17Å; T171-H174 WeakPolarHBondContact O-CB 3.4Å; T171-H174 PolarHBondContact O-N 2.94Å; T171-H174 PolarHBondContact OG1-ND1 2.91Å; H174-A176 PolarHBondContact O-N 2.78Å; H174-C177 WeakPolarHBondContact O-CB 3.3Å; H174-C177 PolarHBondContact O-N 2.97Å; H174-Q178 WeakPolarHBondContact O-CB 3.32Å; H174-Q178 PolarHBondContact O-N 2.99Å; H174-R197 PolarHBondContact CE1-O 3.34Å; H174-R197 PolarHBondContact NE2-O 3.27Å; H174-A203 PolarHBondContact NE2-O 2.77Å; H174-F208 HydrophobicContact CB-CD2 4.19Å; H174-F208 HydrophobicContact CB-CE2 4.4Å; H174-F208 AromaticContact CD2-CD2 3.58Å; H174-F208 AromaticContact CD2-CE2 3.63Å
175V96.1Very high95.6Very high10 Ų1034 Ų346%0.06119%0.186CC..Hα-helixtrans-63.7-41.9-179.4178.60000111.8A144 V145 T171 A172 L173 C177 Q178 N179A144-V175 HydrophobicContact CB-CB 4.25Å; A144-V175 HydrophobicContact CB-CG1 4.21Å; V145-V175 HydrophobicContact CB-CG1 4.14Å; V145-V175 HydrophobicContact CG2-CG1 3.39Å; T171-V175 PolarHBondContact O-N 3.45Å; A172-V175 PolarHBondContact O-N 3.08Å; L173-V175 VanDerWaalsContact C-N 3.34Å; L173-V175 PolarHBondContact O-N 3.38Å; V175-C177 VanDerWaalsContact C-N 3.35Å; V175-Q178 PolarHBondContact O-N 3.45Å; V175-N179 PolarHBondContact O-N 3.1Å; V175-N179 PolarHBondContact O-ND2 2.84Å
176A96.9Very high95.7Very high0 Ų032.6 Ų32.60%018%0.181CC..Hα-helixtrans-64.8-39.7176.600000111.8A144 A172 L173 H174 G180 H181 T184 V185 L188A144-A176 HydrophobicContact CB-CB 4.2Å; A172-A176 WeakPolarHBondContact O-CB 3.45Å; A172-A176 PolarHBondContact O-N 3.18Å; L173-A176 PolarHBondContact O-N 3.22Å; H174-A176 PolarHBondContact O-N 2.78Å; A176-G180 PolarHBondContact O-N 3.26Å; A176-G180 VanDerWaalsContact O-N 3.11Å; A176-H181 PolarHBondContact O-N 3.08Å; A176-T184 HydrophobicContact CB-CG2 3.9Å; A176-V185 HydrophobicContact CB-CG2 3.77Å; A176-L188 HydrophobicContact CB-CD1 4.04Å
177C97.3Very high95.8Very high0 Ų032 Ų320%018%0.178CC..Hα-helixtrans-66.2-42175.5-71.30000112.3L173 H174 V175 N179 G180 P205 F208 A209 Q214L173-C177 WeakPolarHBondContact O-CB 3.41Å; L173-C177 PolarHBondContact O-N 3.48Å; L173-C177 PolarHBondContact O-SG 3.49Å; H174-C177 WeakPolarHBondContact O-CB 3.3Å; H174-C177 PolarHBondContact O-N 2.97Å; V175-C177 VanDerWaalsContact C-N 3.35Å; C177-N179 VanDerWaalsContact C-N 3.32Å; C177-N179 PolarHBondContact O-N 3.22Å; C177-G180 PolarHBondContact O-N 3.11Å; C177-P205 WeakPolarHBondContact CB-O 3.34Å; C177-F208 HydrophobicContact CB-CB 4.37Å; C177-A209 HydrophobicContact CB-CB 4.18Å; C177-Q214 WeakPolarHBondContact O-CG 3.37Å
178Q95.9Very high95.9Very high56 Ų5628.9 Ų28.926%0.26215%0.152SC..Hα-helixtrans-58-43.5175.9-177.3174.6-8.100112.3H174 V175 F208 H212 Q214H174-Q178 WeakPolarHBondContact O-CB 3.32Å; H174-Q178 PolarHBondContact O-N 2.99Å; V175-Q178 PolarHBondContact O-N 3.45Å; Q178-F208 HydrophobicContact CB-CB 4.26Å; Q178-F208 HydrophobicContact CB-CD1 4.06Å; Q178-F208 HydrophobicContact CG-CD1 4.29Å; Q178-H212 WeakPolarHBondContact CG-NE2 3.29Å; Q178-H212 PolarHBondContact NE2-NE2 3.11Å; Q178-H212 WeakPolarHBondContact O-CB 3.3Å; Q178-Q214 PolarHBondContact O-NE2 2.66Å
179N94.8Very high96.1Very high67 Ų6724.2 Ų24.236%0.35813%0.13SC..THydrogen-bonded Turntrans-89.3-1.3-176.1-68.4-78.5000114V175 C177 H181V175-N179 PolarHBondContact O-N 3.1Å; V175-N179 PolarHBondContact O-ND2 2.84Å; C177-N179 VanDerWaalsContact C-N 3.32Å; C177-N179 PolarHBondContact O-N 3.22Å; N179-H181 WeakPolarHBondContact CB-CD2 3.45Å; N179-H181 WeakPolarHBondContact CB-NE2 3.33Å; N179-H181 PolarHBondContact O-N 3.2Å
180G95.3Very high96.1Very high20 Ų2029.1 Ų29.121%0.20616%0.155CC..THydrogen-bonded Turntrans77.316.2176.300000115.7A176 C177 K182A176-G180 PolarHBondContact O-N 3.26Å; A176-G180 VanDerWaalsContact O-N 3.11Å; C177-G180 PolarHBondContact O-N 3.11Å; G180-K182 VanDerWaalsContact C-N 3.32Å; G180-K182 PolarHBondContact O-N 2.97Å
181H96.6Very high95.9Very high52 Ų5229.7 Ų29.724%0.24116%0.162CC..  trans-79.675.3-174.1-64.1-52.5000112.2A144 V145 G147 A176 N179 T183 T184 V185A144-H181 PolarHBondContact O-CD2 2.85Å; V145-H181 PolarHBondContact O-NE2 2.89Å; G147-H181 VanDerWaalsContact CA-CD2 3.48Å; G147-H181 WeakPolarHBondContact CA-CD2 3.39Å; G147-H181 PolarHBondContact N-CD2 3.08Å; G147-H181 VanDerWaalsContact N-CD2 3.33Å; G147-H181 PolarHBondContact N-NE2 3.39Å; A176-H181 PolarHBondContact O-N 3.08Å; N179-H181 WeakPolarHBondContact CB-CD2 3.45Å; N179-H181 WeakPolarHBondContact CB-NE2 3.33Å; N179-H181 PolarHBondContact O-N 3.2Å; H181-T183 VanDerWaalsContact C-N 3.31Å; H181-T183 PolarHBondContact O-N 3.13Å; H181-T183 VanDerWaalsContact O-N 3.16Å; H181-T184 WeakPolarHBondContact O-CA 3.43Å; H181-T184 VanDerWaalsContact O-CB 3.3Å; H181-T184 WeakPolarHBondContact O-CB 3.39Å; H181-T184 PolarHBondContact O-N 3.07Å; H181-V185 PolarHBondContact O-N 2.86Å
182K95.7Very high95.7Very high96 Ų9632.4 Ų32.442%0.41719%0.191SC..Hα-helixtrans-53.5-38.2-172.866.8-176.8173.7-171.30115.7G180 V185 L186 D216 T217 I220G180-K182 VanDerWaalsContact C-N 3.32Å; G180-K182 PolarHBondContact O-N 2.97Å; K182-V185 PolarHBondContact O-N 3.18Å; K182-L186 WeakPolarHBondContact O-CG 3.34Å; K182-L186 PolarHBondContact O-N 3.18Å; K182-D216 HydrophobicContact CB-CB 4.34Å; K182-D216 HydrophobicContact CD-CB 3.89Å; K182-D216 WeakPolarHBondContact CD-OD2 3.5Å; K182-D216 IonicContact NZ-OD2 3.48Å; K182-D216 PolarHBondContact NZ-OD2 3.07Å; K182-T217 HydrophobicContact CB-CG2 4.25Å; K182-I220 HydrophobicContact CB-CD1 3.7Å
183T96.4Very high95.7Very high80 Ų8032.9 Ų32.949%0.49120%0.195SC..Hα-helixtrans-72.4-34178.756.30000111.5T149 H181 C187T149-T183 WeakPolarHBondContact CG2-O 3.42Å; T149-T183 PolarHBondContact OG1-OG1 2.97Å; H181-T183 VanDerWaalsContact C-N 3.31Å; H181-T183 PolarHBondContact O-N 3.13Å; H181-T183 VanDerWaalsContact O-N 3.16Å; T183-C187 WeakPolarHBondContact O-CB 3.48Å; T183-C187 PolarHBondContact O-N 3.41Å
184T96.1Very high95.6Very high0 Ų035.8 Ų35.80%021%0.21CC..Hα-helixtrans-68.2-43.6173.3-520000110.6A144 G147 T149 L152 A176 H181 L186 C187 L188A144-T184 HydrophobicContact CB-CG2 4.32Å; G147-T184 WeakPolarHBondContact CA-OG1 3.43Å; T149-T184 PolarHBondContact OG1-N 3.4Å; T149-T184 VanDerWaalsContact OG1-N 3.17Å; T149-T184 PolarHBondContact OG1-OG1 3.27Å; L152-T184 HydrophobicContact CD2-CG2 3.49Å; L152-T184 VanDerWaalsContact CD2-CG2 3.49Å; A176-T184 HydrophobicContact CB-CG2 3.9Å; H181-T184 WeakPolarHBondContact O-CA 3.43Å; H181-T184 VanDerWaalsContact O-CB 3.3Å; H181-T184 WeakPolarHBondContact O-CB 3.39Å; H181-T184 PolarHBondContact O-N 3.07Å; T184-L186 PolarHBondContact O-N 3.28Å; T184-C187 PolarHBondContact O-N 3.42Å; T184-L188 HydrophobicContact CG2-CD1 4.21Å; T184-L188 WeakPolarHBondContact O-CG 3.38Å; T184-L188 PolarHBondContact O-N 3.46Å
185V96.9Very high95.6Very high0 Ų036.8 Ų36.80%022%0.216CC..Hα-helixtrans-55.8-49.3173.6170.90000110.7L173 A176 H181 K182 C187 L188 L189 T217 I220 L221L173-V185 HydrophobicContact CD1-CB 4.41Å; L173-V185 HydrophobicContact CD1-CG1 3.97Å; L173-V185 HydrophobicContact CD1-CG2 4.44Å; A176-V185 HydrophobicContact CB-CG2 3.77Å; H181-V185 PolarHBondContact O-N 2.86Å; K182-V185 PolarHBondContact O-N 3.18Å; V185-C187 PolarHBondContact O-N 2.87Å; V185-L188 PolarHBondContact O-N 3.25Å; V185-L189 HydrophobicContact CG1-CD1 3.88Å; V185-L189 HydrophobicContact CG1-CG 4.43Å; V185-L189 VanDerWaalsContact O-CG 3.26Å; V185-L189 WeakPolarHBondContact O-CG 3.37Å; V185-L189 PolarHBondContact O-N 3.18Å; V185-T217 HydrophobicContact CG2-CG2 4.04Å; V185-I220 HydrophobicContact CG1-CG2 4.11Å; V185-L221 HydrophobicContact CG1-CD2 4.34Å
186L96.6Very high95.6Very high54 Ų5437.7 Ų37.728%0.28322%0.22SC..Hα-helixtrans-58.9-47.7176-74.5167.6000112K182 T184 L188 L189 D190 I220K182-L186 WeakPolarHBondContact O-CG 3.34Å; K182-L186 PolarHBondContact O-N 3.18Å; T184-L186 PolarHBondContact O-N 3.28Å; L186-L188 VanDerWaalsContact C-N 3.33Å; L186-L188 PolarHBondContact O-N 3.48Å; L186-L189 PolarHBondContact O-N 3.28Å; L186-D190 WeakPolarHBondContact O-CB 3.49Å; L186-D190 PolarHBondContact O-N 2.7Å; L186-I220 HydrophobicContact CD1-CD1 4.13Å; L186-I220 HydrophobicContact CD2-CD1 4.42Å; L186-I220 HydrophobicContact CD2-CG1 4.45Å; L186-I220 HydrophobicContact CD2-CG2 3.58Å; L186-I220 HydrophobicContact CG-CD1 4.06Å; L186-I220 HydrophobicContact CG-CG2 4.09Å
187C95.1Very high95.5Very high13 Ų1342.3 Ų42.39%0.08824%0.237CC..Hα-helixtrans-58.9-42.6179.1-173.70000112.2T149 L152 T183 T184 V185 S191T149-C187 HydrophobicContact CG2-CB 3.87Å; L152-C187 HydrophobicContact CD2-CB 4.03Å; T183-C187 WeakPolarHBondContact O-CB 3.48Å; T183-C187 PolarHBondContact O-N 3.41Å; T184-C187 PolarHBondContact O-N 3.42Å; V185-C187 PolarHBondContact O-N 2.87Å; C187-S191 VanDerWaalsContact O-CB 3.32Å; C187-S191 WeakPolarHBondContact O-CB 3.36Å; C187-S191 PolarHBondContact O-N 3.41Å; C187-S191 VanDerWaalsContact O-N 3.11Å; C187-S191 PolarHBondContact O-OG 3.01Å
188L95.4Very high95.4Very high1 Ų145.6 Ų45.61%0.00526%0.259CS..Hα-helixtrans-66.3-44.6177.8-70.1171.2000111.7I140 L152 A172 L173 A176 T184 V185 L186 S191 G192 A193I140-L188 HydrophobicContact CD1-CD2 3.81Å; I140-L188 HydrophobicContact CG1-CD2 4.26Å; L152-L188 HydrophobicContact CD1-CD2 4.01Å; L152-L188 HydrophobicContact CD2-CD1 4.5Å; L152-L188 HydrophobicContact CD2-CD2 3.77Å; L152-L188 HydrophobicContact CD2-CG 3.76Å; L152-L188 HydrophobicContact CG-CD2 4.4Å; A172-L188 HydrophobicContact CB-CD1 4.07Å; A172-L188 HydrophobicContact CB-CD2 4.26Å; A172-L188 WeakPolarHBondContact O-CD1 3.4Å; L173-L188 HydrophobicContact CB-CD1 4.21Å; L173-L188 HydrophobicContact CD1-CB 4.19Å; L173-L188 HydrophobicContact CD1-CD1 4.33Å; A176-L188 HydrophobicContact CB-CD1 4.04Å; T184-L188 HydrophobicContact CG2-CD1 4.21Å; T184-L188 WeakPolarHBondContact O-CG 3.38Å; T184-L188 PolarHBondContact O-N 3.46Å; V185-L188 PolarHBondContact O-N 3.25Å; L186-L188 VanDerWaalsContact C-N 3.33Å; L186-L188 PolarHBondContact O-N 3.48Å; L188-S191 CarbonylContact O-C 3.27Å; L188-S191 PolarHBondContact O-N 2.97Å; L188-G192 PolarHBondContact O-N 3.49Å; L188-A193 HydrophobicContact CB-CB 4.17Å; L188-A193 VanDerWaalsContact O-CB 3.23Å; L188-A193 WeakPolarHBondContact O-CB 3.49Å; L188-A193 PolarHBondContact O-N 3.37Å; L188-A193 VanDerWaalsContact O-N 3.08Å
189L95.6Very high95.4Very high21 Ų2143.6 Ų43.611%0.1125%0.25CC..Hα-helixtrans-64.2-42.7177.4-68.2173.9000112L173 V185 L186 S191 G192 I195 I220 L221 R224L173-L189 HydrophobicContact CD1-CD2 4.23Å; L173-L189 HydrophobicContact CD1-CG 4.2Å; L173-L189 HydrophobicContact CD2-CD2 3.73Å; V185-L189 HydrophobicContact CG1-CD1 3.88Å; V185-L189 HydrophobicContact CG1-CG 4.43Å; V185-L189 VanDerWaalsContact O-CG 3.26Å; V185-L189 WeakPolarHBondContact O-CG 3.37Å; V185-L189 PolarHBondContact O-N 3.18Å; L186-L189 PolarHBondContact O-N 3.28Å; L189-S191 PolarHBondContact O-N 3.08Å; L189-G192 PolarHBondContact O-N 3.03Å; L189-G192 VanDerWaalsContact O-N 3.1Å; L189-I195 HydrophobicContact CD1-CD1 4.42Å; L189-I195 HydrophobicContact CD2-CB 3.86Å; L189-I195 HydrophobicContact CD2-CD1 4.07Å; L189-I195 HydrophobicContact CD2-CG1 3.84Å; L189-I220 HydrophobicContact CD1-CG2 4.07Å; L189-L221 HydrophobicContact CD1-CD2 4.27Å; L189-R224 HydrophobicContact CD1-CB 4.4Å; L189-R224 HydrophobicContact CD1-CG 4.18Å
190D94.3Very high95.4Very high107 Ų10744.8 Ų44.857%0.57226%0.259SS*.Hα-helixtrans-66.3-22177-66.3-15.7000111.9L186 G192 R224L186-D190 WeakPolarHBondContact O-CB 3.49Å; L186-D190 PolarHBondContact O-N 2.7Å; D190-G192 VanDerWaalsContact C-N 3.34Å; D190-R224 IonicContact OD1-CZ 2.77Å; D190-R224 VanDerWaalsContact OD1-CZ 3.25Å; D190-R224 IonicContact OD1-NH1 2.98Å; D190-R224 PolarHBondContact OD1-NH1 3.28Å; D190-R224 IonicContact OD1-NH2 2.72Å; D190-R224 PolarHBondContact OD1-NH2 3.5Å; D190-R224 IonicContact OD2-NH2 2.95Å
191S92.5Very high95.3Very high44 Ų4446.4 Ų46.431%0.30827%0.267SS..THydrogen-bonded Turntrans-929.3175.7-53.10000113.9V156 C187 L188 L189V156-S191 VanDerWaalsContact CG1-CB 3.47Å; V156-S191 WeakPolarHBondContact CG1-OG 3.5Å; C187-S191 VanDerWaalsContact O-CB 3.32Å; C187-S191 WeakPolarHBondContact O-CB 3.36Å; C187-S191 PolarHBondContact O-N 3.41Å; C187-S191 VanDerWaalsContact O-N 3.11Å; C187-S191 PolarHBondContact O-OG 3.01Å; L188-S191 CarbonylContact O-C 3.27Å; L188-S191 PolarHBondContact O-N 2.97Å; L189-S191 PolarHBondContact O-N 3.08Å
192G92.3Very high95.1Very high58 Ų5844.6 Ų44.660%0.59826%0.263SS*.THydrogen-bonded Turntrans90.716.8172.600000116L188 L189 D190L188-G192 PolarHBondContact O-N 3.49Å; L189-G192 PolarHBondContact O-N 3.03Å; L189-G192 VanDerWaalsContact O-N 3.1Å; D190-G192 VanDerWaalsContact C-N 3.34Å
193A95.5Very high95.1Very high10 Ų1040.1 Ų40.18%0.08324%0.244CC..  trans-63.2136.217400000111.9V162 D163 L173 L188 I195V162-A193 HydrophobicContact CG2-CB 3.76Å; D163-A193 WeakPolarHBondContact OD1-CA 3.44Å; L173-A193 HydrophobicContact CB-CB 4.49Å; L173-A193 HydrophobicContact CD2-CB 4.15Å; L188-A193 HydrophobicContact CB-CB 4.17Å; L188-A193 VanDerWaalsContact O-CB 3.23Å; L188-A193 WeakPolarHBondContact O-CB 3.49Å; L188-A193 PolarHBondContact O-N 3.37Å; L188-A193 VanDerWaalsContact O-N 3.08Å; A193-I195 PolarHBondContact O-N 3.11Å; A193-I195 VanDerWaalsContact O-N 3.14Å
194D96Very high95.1Very high62 Ų6236.4 Ų36.433%0.33222%0.221SC..  trans-71.2107.4177.3-179.71.6000111.1D163 N196 R197D163-D194 PolarHBondContact OD1-N 2.81Å; D163-D194 WeakPolarHBondContact OD2-CB 3.26Å; D163-D194 PolarHBondContact OD2-N 3.33Å; D194-N196 PolarHBondContact O-N 2.91Å; D194-N196 VanDerWaalsContact O-N 3.1Å; D194-N196 PolarHBondContact OD1-N 3.47Å; D194-R197 HydrophobicContact CB-CB 4.04Å; D194-R197 WeakPolarHBondContact O-CB 3.41Å; D194-R197 PolarHBondContact O-N 2.99Å
195I96.6Very high95.2Very high22 Ų2236.4 Ų36.411%0.11322%0.221CC..THydrogen-bonded Turntrans-60.1-20.9-178.3-162169.8000114.3L189 A193 L221 R224 A226L189-I195 HydrophobicContact CD1-CD1 4.42Å; L189-I195 HydrophobicContact CD2-CB 3.86Å; L189-I195 HydrophobicContact CD2-CD1 4.07Å; L189-I195 HydrophobicContact CD2-CG1 3.84Å; A193-I195 PolarHBondContact O-N 3.11Å; A193-I195 VanDerWaalsContact O-N 3.14Å; I195-L221 HydrophobicContact CD1-CD2 4.02Å; I195-L221 WeakPolarHBondContact CD1-O 3.26Å; I195-L221 HydrophobicContact CG1-CD2 3.62Å; I195-R224 HydrophobicContact CD1-CB 3.6Å; I195-A226 HydrophobicContact CD1-CB 3.87Å; I195-A226 HydrophobicContact CG1-CB 3.92Å
196N96Very high95.2Very high29 Ų2936.5 Ų36.516%0.15522%0.221CC..THydrogen-bonded Turntrans-115.79.9-175.8-65.6-57.8000113.4D194 P198 K227D194-N196 PolarHBondContact O-N 2.91Å; D194-N196 VanDerWaalsContact O-N 3.1Å; D194-N196 PolarHBondContact OD1-N 3.47Å; N196-P198 VanDerWaalsContact O-CD 3.32Å; N196-P198 WeakPolarHBondContact O-CD 3.42Å; N196-K227 WeakPolarHBondContact OD1-CB 3.33Å; N196-K227 PolarHBondContact OD1-N 3.16Å
197R95.2Very high95.2Very high96 Ų9635.5 Ų35.536%0.36221%0.214SC..  trans-58.8121-179-162.677.4179-166.7-2.7110.2E165 T171 H174 D194 P205E165-R197 IonicContact OE1-CZ 2.78Å; E165-R197 IonicContact OE1-NE 3.56Å; E165-R197 PolarHBondContact OE1-NE 3.03Å; E165-R197 VanDerWaalsContact OE1-NE 3.08Å; E165-R197 IonicContact OE1-NH2 3.73Å; E165-R197 PolarHBondContact OE1-NH2 2.73Å; T171-R197 HydrophobicContact CG2-CG 4.32Å; H174-R197 PolarHBondContact CE1-O 3.34Å; H174-R197 PolarHBondContact NE2-O 3.27Å; D194-R197 HydrophobicContact CB-CB 4.04Å; D194-R197 WeakPolarHBondContact O-CB 3.41Å; D194-R197 PolarHBondContact O-N 2.99Å; R197-P205 WeakPolarHBondContact O-CD 3.42Å
198P95.4Very high95.2Very high69 Ų6935.8 Ų35.845%0.44821%0.214SC..  trans-86.7143.9176.532.4-31.4000111.3N196 A203N196-P198 VanDerWaalsContact O-CD 3.32Å; N196-P198 WeakPolarHBondContact O-CD 3.42Å; P198-A203 WeakPolarHBondContact CA-O 3.46Å
199N94.9Very high95.3Very high15 Ų1535.7 Ų35.78%0.0821%0.214CC..  trans-77.5-173.3169.179.4-11.1000112.2G169 Q170 S201 G202 A203G169-N199 WeakPolarHBondContact O-CA 3.48Å; G169-N199 WeakPolarHBondContact O-CB 3.36Å; Q170-N199 HydrophobicContact CG-CB 4.16Å; N199-S201 PolarHBondContact ND2-OG 3.01Å; N199-S201 PolarHBondContact O-N 3.27Å; N199-S201 WeakPolarHBondContact OD1-CA 3.38Å; N199-S201 PolarHBondContact OD1-N 3.38Å; N199-S201 PolarHBondContact OD1-OG 3.06Å; N199-G202 PolarHBondContact O-N 2.82Å; N199-G202 PolarHBondContact OD1-N 2.84Å; N199-G202 VanDerWaalsContact OD1-N 3.08Å; N199-A203 PolarHBondContact N-O 2.94Å; N199-A203 WeakPolarHBondContact OD1-CB 3.46Å; N199-A203 PolarHBondContact OD1-N 2.86Å; N199-A203 PolarHBondContact OD1-O 2.98Å
200V94.8Very high95.3Very high92 Ų9234.7 Ų34.756%0.55821%0.208SC*.THydrogen-bonded Turntrans-59.7-28.7179.3174.30000113.1M168 K232M168-V200 VanDerWaalsContact C-CG2 3.5Å; M168-V200 WeakPolarHBondContact O-CB 3.44Å; M168-V200 VanDerWaalsContact O-CG2 3.3Å; M168-V200 WeakPolarHBondContact O-CG2 3.28Å; M168-V200 PolarHBondContact O-N 3.36Å; V200-K232 VanDerWaalsContact O-CE 3.28Å; V200-K232 WeakPolarHBondContact O-CE 3.45Å; V200-K232 PolarHBondContact O-NZ 2.88Å
201S93.2Very high95.4Very high53 Ų5330.9 Ų30.937%0.37119%0.19SC..THydrogen-bonded Turntrans-87.80.6175.865.50000114N199 A203 K232N199-S201 PolarHBondContact ND2-OG 3.01Å; N199-S201 PolarHBondContact O-N 3.27Å; N199-S201 WeakPolarHBondContact OD1-CA 3.38Å; N199-S201 PolarHBondContact OD1-N 3.38Å; N199-S201 PolarHBondContact OD1-OG 3.06Å; S201-A203 VanDerWaalsContact C-N 3.31Å; S201-K232 VanDerWaalsContact O-CB 3.32Å; S201-K232 WeakPolarHBondContact O-CB 3.25Å; S201-K232 VanDerWaalsContact O-CG 3.25Å; S201-K232 WeakPolarHBondContact O-CG 3.32Å; S201-K232 PolarHBondContact O-N 2.82Å
202G93.6Very high95.5Very high15 Ų1532.4 Ų32.416%0.15519%0.192CC..SBendtrans81.45.5-174.600000114.4N199N199-G202 PolarHBondContact O-N 2.82Å; N199-G202 PolarHBondContact OD1-N 2.84Å; N199-G202 VanDerWaalsContact OD1-N 3.08Å
203A95.4Very high95.6Very high1 Ų130.6 Ų30.61%0.00817%0.173CC..  trans-77.6134.2177.900000110.9H174 P198 N199 S201 Y207 F208H174-A203 PolarHBondContact NE2-O 2.77Å; P198-A203 WeakPolarHBondContact CA-O 3.46Å; N199-A203 PolarHBondContact N-O 2.94Å; N199-A203 WeakPolarHBondContact OD1-CB 3.46Å; N199-A203 PolarHBondContact OD1-N 2.86Å; N199-A203 PolarHBondContact OD1-O 2.98Å; S201-A203 VanDerWaalsContact C-N 3.31Å; A203-Y207 HydrophobicContact CB-CD1 3.52Å; A203-Y207 HydrophobicContact CB-CD2 4.08Å; A203-Y207 HydrophobicContact CB-CE1 3.89Å; A203-Y207 HydrophobicContact CB-CE2 4.39Å; A203-Y207 HydrophobicContact CB-CG 3.64Å; A203-F208 HydrophobicContact CB-CD2 4.39Å; A203-F208 HydrophobicContact CB-CE2 3.81Å
204T96.6Very high95.7Very high3 Ų332.8 Ų32.82%0.01818%0.182CC..  trans-96.8170.418062.30000111.8L206 Y207 F208 L229T204-L206 PolarHBondContact O-N 3.17Å; T204-Y207 WeakPolarHBondContact O-CA 3.32Å; T204-Y207 WeakPolarHBondContact O-CB 3.46Å; T204-Y207 PolarHBondContact O-N 2.7Å; T204-Y207 PolarHBondContact OG1-N 2.94Å; T204-F208 WeakPolarHBondContact O-CD2 3.19Å; T204-F208 PolarHBondContact O-N 3.07Å; T204-L229 HydrophobicContact CG2-CB 4.32Å; T204-L229 HydrophobicContact CG2-CD1 4.24Å
205P97.1Very high95.7Very high0 Ų033.8 Ų33.80%018%0.181CC..Hα-helixtrans-56-35.5173.2-28.536.4000113.9L173 C177 R197 Y207 F208 A209 L221L173-P205 HydrophobicContact CB-CG 4.49Å; L173-P205 HydrophobicContact CD2-CB 4.1Å; L173-P205 HydrophobicContact CD2-CG 3.76Å; L173-P205 HydrophobicContact CG-CB 3.92Å; L173-P205 HydrophobicContact CG-CG 3.91Å; C177-P205 WeakPolarHBondContact CB-O 3.34Å; R197-P205 WeakPolarHBondContact O-CD 3.42Å; P205-Y207 VanDerWaalsContact C-N 3.33Å; P205-Y207 PolarHBondContact O-N 2.86Å; P205-F208 PolarHBondContact O-N 3.2Å; P205-A209 PolarHBondContact O-N 3.38Å; P205-A209 VanDerWaalsContact O-N 3.07Å; P205-L221 HydrophobicContact CB-CD1 4.25Å; P205-L221 HydrophobicContact CB-CD2 4.3Å
206L97.1Very high95.6Very high1 Ų135.2 Ų35.21%0.00519%0.189CC..Hα-helixtrans-63.9-38.1174.7-177.163.8000111.8T204 F208 A209 C210 A218 L221 L222 A226 P237T204-L206 PolarHBondContact O-N 3.17Å; L206-F208 VanDerWaalsContact C-N 3.34Å; L206-F208 PolarHBondContact O-N 2.83Å; L206-A209 PolarHBondContact O-N 2.91Å; L206-C210 WeakPolarHBondContact O-CB 3.48Å; L206-C210 PolarHBondContact O-N 3.33Å; L206-C210 PolarHBondContact O-SG 3.25Å; L206-C210 VanDerWaalsContact O-SG 3.33Å; L206-A218 HydrophobicContact CD1-CB 4.11Å; L206-L221 HydrophobicContact CB-CD1 4.1Å; L206-L221 HydrophobicContact CD1-CB 4.27Å; L206-L221 HydrophobicContact CD1-CD1 4.18Å; L206-L222 HydrophobicContact CD1-CD2 4.33Å; L206-L222 HydrophobicContact CD1-CG 4.16Å; L206-L222 HydrophobicContact CD2-CD2 3.82Å; L206-A226 HydrophobicContact CD2-CB 4.42Å; L206-P237 HydrophobicContact CD2-CG 4.47Å
207Y96.3Very high95.7Very high34 Ų3433.9 Ų33.913%0.13318%0.182CC..Hα-helixtrans-58.3-44.8173.8-177.4-74.8000111.6A203 T204 P205 C210 S211 D231 I235 L240A203-Y207 HydrophobicContact CB-CD1 3.52Å; A203-Y207 HydrophobicContact CB-CD2 4.08Å; A203-Y207 HydrophobicContact CB-CE1 3.89Å; A203-Y207 HydrophobicContact CB-CE2 4.39Å; A203-Y207 HydrophobicContact CB-CG 3.64Å; T204-Y207 WeakPolarHBondContact O-CA 3.32Å; T204-Y207 WeakPolarHBondContact O-CB 3.46Å; T204-Y207 PolarHBondContact O-N 2.7Å; T204-Y207 PolarHBondContact OG1-N 2.94Å; P205-Y207 VanDerWaalsContact C-N 3.33Å; P205-Y207 PolarHBondContact O-N 2.86Å; Y207-C210 PolarHBondContact O-N 2.98Å; Y207-S211 WeakPolarHBondContact O-CB 3.32Å; Y207-S211 PolarHBondContact O-N 3.02Å; Y207-S211 PolarHBondContact O-OG 3.26Å; Y207-D231 HydrophobicContact CD2-CB 4.21Å; Y207-D231 HydrophobicContact CE2-CB 3.67Å; Y207-D231 PolarHBondContact OH-OD2 2.93Å; Y207-I235 HydrophobicContact CE2-CB 4.49Å; Y207-I235 HydrophobicContact CE2-CG2 4.42Å; Y207-L240 HydrophobicContact CD1-CD1 3.62Å; Y207-L240 HydrophobicContact CD2-CD1 3.4Å; Y207-L240 HydrophobicContact CE1-CD1 3.6Å; Y207-L240 HydrophobicContact CE1-CD2 4.3Å; Y207-L240 HydrophobicContact CE2-CD1 3.38Å; Y207-L240 HydrophobicContact CE2-CD2 4.29Å; Y207-L240 HydrophobicContact CE2-CG 4.19Å; Y207-L240 HydrophobicContact CG-CD1 3.51Å; Y207-L240 VanDerWaalsContact CZ-CD1 3.49Å
208F95.9Very high95.8Very high18 Ų1829.3 Ų29.38%0.07917%0.165CC..Hα-helixtrans-67.7-39.9178.9-80.6-90.4000112.8Q170 H174 C177 Q178 A203 T204 P205 L206 C210 S211 H212Q170-F208 HydrophobicContact CG-CZ 4.22Å; H174-F208 HydrophobicContact CB-CD2 4.19Å; H174-F208 HydrophobicContact CB-CE2 4.4Å; H174-F208 AromaticContact CD2-CD2 3.58Å; H174-F208 AromaticContact CD2-CE2 3.63Å; C177-F208 HydrophobicContact CB-CB 4.37Å; Q178-F208 HydrophobicContact CB-CB 4.26Å; Q178-F208 HydrophobicContact CB-CD1 4.06Å; Q178-F208 HydrophobicContact CG-CD1 4.29Å; A203-F208 HydrophobicContact CB-CD2 4.39Å; A203-F208 HydrophobicContact CB-CE2 3.81Å; T204-F208 WeakPolarHBondContact O-CD2 3.19Å; T204-F208 PolarHBondContact O-N 3.07Å; P205-F208 PolarHBondContact O-N 3.2Å; L206-F208 VanDerWaalsContact C-N 3.34Å; L206-F208 PolarHBondContact O-N 2.83Å; F208-C210 VanDerWaalsContact C-N 3.33Å; F208-C210 PolarHBondContact O-N 3.08Å; F208-S211 WeakPolarHBondContact CA-OG 3.14Å; F208-S211 PolarHBondContact O-OG 3.1Å; F208-H212 PolarHBondContact O-N 2.97Å; F208-H212 PolarHBondContact O-ND1 3.28Å
209A96.8Very high95.8Very high0 Ų028.9 Ų28.90%016%0.157CC..Hα-helixtrans-59.8-44.7173.200000111.6C177 P205 L206 G213 Q214 T217 A218 L221C177-A209 HydrophobicContact CB-CB 4.18Å; P205-A209 PolarHBondContact O-N 3.38Å; P205-A209 VanDerWaalsContact O-N 3.07Å; L206-A209 PolarHBondContact O-N 2.91Å; A209-G213 PolarHBondContact O-N 3.19Å; A209-Q214 HydrophobicContact CB-CB 4.39Å; A209-Q214 PolarHBondContact O-N 2.96Å; A209-T217 VanDerWaalsContact CB-OG1 3.29Å; A209-T217 WeakPolarHBondContact CB-OG1 3.45Å; A209-A218 HydrophobicContact CB-CB 4.16Å; A209-L221 HydrophobicContact CB-CD1 4.19Å
210C96.4Very high95.9Very high0 Ų029.4 Ų29.40%016%0.159CC..Hα-helixtrans-70-41.7-179.5-73.30000113.6L206 Y207 F208 H212 G213 P237 C241 Y246L206-C210 WeakPolarHBondContact O-CB 3.48Å; L206-C210 PolarHBondContact O-N 3.33Å; L206-C210 PolarHBondContact O-SG 3.25Å; L206-C210 VanDerWaalsContact O-SG 3.33Å; Y207-C210 PolarHBondContact O-N 2.98Å; F208-C210 VanDerWaalsContact C-N 3.33Å; F208-C210 PolarHBondContact O-N 3.08Å; C210-H212 PolarHBondContact O-N 3.14Å; C210-G213 PolarHBondContact O-N 3.21Å; C210-P237 HydrophobicContact CB-CB 3.96Å; C210-P237 WeakPolarHBondContact CB-O 3.49Å; C210-C241 WeakPolarHBondContact CB-SG 3.36Å; C210-C241 VanDerWaalsContact SG-SG 3.65Å; C210-Y246 VanDerWaalsContact O-CD2 3.28Å; C210-Y246 WeakPolarHBondContact O-CD2 3.35Å
211S95.7Very high96Very high27 Ų2725 Ų2519%0.18913%0.133CC..Hα-helixtrans-66.1-14.6177.954.90000114.9Y207 F208 Y246Y207-S211 WeakPolarHBondContact O-CB 3.32Å; Y207-S211 PolarHBondContact O-N 3.02Å; Y207-S211 PolarHBondContact O-OG 3.26Å; F208-S211 WeakPolarHBondContact CA-OG 3.14Å; F208-S211 PolarHBondContact O-OG 3.1Å; S211-Y246 WeakPolarHBondContact O-CE2 3.32Å
212H94.9Very high96.1Very high75 Ų7523 Ų2335%0.34712%0.118SC..THydrogen-bonded Turntrans-119.310.2178.3-65.669000112.5Q178 F208 C210 Q214Q178-H212 WeakPolarHBondContact CG-NE2 3.29Å; Q178-H212 PolarHBondContact NE2-NE2 3.11Å; Q178-H212 WeakPolarHBondContact O-CB 3.3Å; F208-H212 PolarHBondContact O-N 2.97Å; F208-H212 PolarHBondContact O-ND1 3.28Å; C210-H212 PolarHBondContact O-N 3.14Å; H212-Q214 VanDerWaalsContact C-N 3.33Å; H212-Q214 HydrophobicContact CB-CG 3.93Å; H212-Q214 PolarHBondContact O-N 3.19Å
213G94.9Very high96.2Very high20 Ų2025.9 Ų25.921%0.20614%0.135CC..THydrogen-bonded Turntrans67.626.817500000115.3A209 C210 R215 Y246 T249A209-G213 PolarHBondContact O-N 3.19Å; C210-G213 PolarHBondContact O-N 3.21Å; G213-R215 VanDerWaalsContact C-N 3.35Å; G213-R215 PolarHBondContact O-N 3.39Å; G213-Y246 VanDerWaalsContact CA-CD2 3.4Å; G213-Y246 VanDerWaalsContact N-CD2 3.31Å; G213-Y246 VanDerWaalsContact N-CE2 3.31Å; G213-T249 PolarHBondContact O-OG1 3.3Å
214Q96.6Very high96.2Very high57 Ų5731.1 Ų31.127%0.26616%0.155SC..  trans-85.171.2-170.8-56.9-66.8-0.500112.1C177 Q178 A209 H212 D216 T217 A218C177-Q214 WeakPolarHBondContact O-CG 3.37Å; Q178-Q214 PolarHBondContact O-NE2 2.66Å; A209-Q214 HydrophobicContact CB-CB 4.39Å; A209-Q214 PolarHBondContact O-N 2.96Å; H212-Q214 VanDerWaalsContact C-N 3.33Å; H212-Q214 HydrophobicContact CB-CG 3.93Å; H212-Q214 PolarHBondContact O-N 3.19Å; Q214-D216 PolarHBondContact O-N 3.03Å; Q214-T217 HydrophobicContact CB-CG2 4.39Å; Q214-T217 WeakPolarHBondContact CB-OG1 3.35Å; Q214-T217 PolarHBondContact O-N 3.36Å; Q214-T217 PolarHBondContact O-OG1 2.84Å; Q214-A218 PolarHBondContact O-N 3.07Å
215R95.4Very high96Very high82 Ų8233.3 Ų33.331%0.30918%0.178SC..Hα-helixtrans-45.5-54.2-173.7-176.1-174.562.662.310.1114.4G213 T217 A218 Q219 E248 T249 I252G213-R215 VanDerWaalsContact C-N 3.35Å; G213-R215 PolarHBondContact O-N 3.39Å; R215-T217 VanDerWaalsContact C-N 3.3Å; R215-T217 PolarHBondContact O-N 3.48Å; R215-A218 PolarHBondContact O-N 2.76Å; R215-Q219 WeakPolarHBondContact O-CB 3.27Å; R215-Q219 PolarHBondContact O-N 3.06Å; R215-E248 HydrophobicContact CB-CB 4.41Å; R215-E248 VanDerWaalsContact CD-CB 3.48Å; R215-E248 VanDerWaalsContact CD-OE2 3.29Å; R215-E248 WeakPolarHBondContact CD-OE2 3.3Å; R215-E248 HydrophobicContact CG-CB 4.21Å; R215-E248 IonicContact NE-OE2 2.73Å; R215-E248 PolarHBondContact NE-OE2 2.9Å; R215-T249 WeakPolarHBondContact CA-OG1 3.41Å; R215-T249 PolarHBondContact N-OG1 3.27Å; R215-I252 HydrophobicContact CG-CG1 3.64Å
216D96.4Very high95.9Very high52 Ų5233.7 Ų33.728%0.27818%0.181SC..Hα-helixtrans-61.3-39.6-176.4-81.9-14.8000111.6K182 Q214 I220K182-D216 HydrophobicContact CB-CB 4.34Å; K182-D216 HydrophobicContact CD-CB 3.89Å; K182-D216 WeakPolarHBondContact CD-OD2 3.5Å; K182-D216 IonicContact NZ-OD2 3.48Å; K182-D216 PolarHBondContact NZ-OD2 3.07Å; Q214-D216 PolarHBondContact O-N 3.03Å; D216-I220 WeakPolarHBondContact O-CD1 3.23Å; D216-I220 VanDerWaalsContact O-CG1 3.29Å; D216-I220 WeakPolarHBondContact O-CG1 3.32Å; D216-I220 PolarHBondContact O-N 3.09Å
217T97Very high95.7Very high1 Ų139.9 Ų39.91%0.00621%0.208CC..Hα-helixtrans-71-41.1178.866.60000111.8K182 V185 A209 Q214 R215 Q219 I220 L221K182-T217 HydrophobicContact CB-CG2 4.25Å; V185-T217 HydrophobicContact CG2-CG2 4.04Å; A209-T217 VanDerWaalsContact CB-OG1 3.29Å; A209-T217 WeakPolarHBondContact CB-OG1 3.45Å; Q214-T217 HydrophobicContact CB-CG2 4.39Å; Q214-T217 WeakPolarHBondContact CB-OG1 3.35Å; Q214-T217 PolarHBondContact O-N 3.36Å; Q214-T217 PolarHBondContact O-OG1 2.84Å; R215-T217 VanDerWaalsContact C-N 3.3Å; R215-T217 PolarHBondContact O-N 3.48Å; T217-Q219 VanDerWaalsContact C-N 3.33Å; T217-Q219 PolarHBondContact O-N 3.46Å; T217-I220 PolarHBondContact O-N 3.27Å; T217-L221 VanDerWaalsContact O-CG 3.3Å; T217-L221 WeakPolarHBondContact O-CG 3.34Å; T217-L221 PolarHBondContact O-N 3.49Å
218A96.7Very high95.5Very high0 Ų040.9 Ų40.90%021%0.212CC..Hα-helixtrans-60.8-43.1174.600000111.2L206 A209 Q214 R215 I220 L221 L222 T249L206-A218 HydrophobicContact CD1-CB 4.11Å; A209-A218 HydrophobicContact CB-CB 4.16Å; Q214-A218 PolarHBondContact O-N 3.07Å; R215-A218 PolarHBondContact O-N 2.76Å; A218-I220 PolarHBondContact O-N 2.86Å; A218-L221 PolarHBondContact O-N 3.06Å; A218-L222 VanDerWaalsContact O-CG 3.3Å; A218-L222 WeakPolarHBondContact O-CG 3.24Å; A218-L222 PolarHBondContact O-N 3.43Å; A218-T249 HydrophobicContact CB-CG2 3.92Å
219Q96.6Very high95.4Very high61 Ų6143.6 Ų43.629%0.28523%0.227SC..Hα-helixtrans-60.9-44.8176178.761.513.500112R215 T217 S223 I252 H256R215-Q219 WeakPolarHBondContact O-CB 3.27Å; R215-Q219 PolarHBondContact O-N 3.06Å; T217-Q219 VanDerWaalsContact C-N 3.33Å; T217-Q219 PolarHBondContact O-N 3.46Å; Q219-S223 VanDerWaalsContact O-CB 3.29Å; Q219-S223 WeakPolarHBondContact O-CB 3.45Å; Q219-S223 PolarHBondContact O-N 3.28Å; Q219-S223 PolarHBondContact O-OG 3.32Å; Q219-I252 HydrophobicContact CB-CG1 4.5Å; Q219-I252 HydrophobicContact CB-CG2 4.05Å; Q219-H256 PolarHBondContact OE1-NE2 3.29Å
220I96.8Very high95.1Very high25 Ų2545.6 Ų45.613%0.12824%0.244CC..Hα-helixtrans-60.8-48.8176.8-71.6161.6000110.2K182 V185 L186 L189 D216 T217 A218 L222 S223 R224K182-I220 HydrophobicContact CB-CD1 3.7Å; V185-I220 HydrophobicContact CG1-CG2 4.11Å; L186-I220 HydrophobicContact CD1-CD1 4.13Å; L186-I220 HydrophobicContact CD2-CD1 4.42Å; L186-I220 HydrophobicContact CD2-CG1 4.45Å; L186-I220 HydrophobicContact CD2-CG2 3.58Å; L186-I220 HydrophobicContact CG-CD1 4.06Å; L186-I220 HydrophobicContact CG-CG2 4.09Å; L189-I220 HydrophobicContact CD1-CG2 4.07Å; D216-I220 WeakPolarHBondContact O-CD1 3.23Å; D216-I220 VanDerWaalsContact O-CG1 3.29Å; D216-I220 WeakPolarHBondContact O-CG1 3.32Å; D216-I220 PolarHBondContact O-N 3.09Å; T217-I220 PolarHBondContact O-N 3.27Å; A218-I220 PolarHBondContact O-N 2.86Å; I220-L222 PolarHBondContact O-N 3.18Å; I220-S223 WeakPolarHBondContact CA-OG 3.42Å; I220-S223 PolarHBondContact O-N 3.37Å; I220-S223 PolarHBondContact O-OG 2.78Å; I220-R224 HydrophobicContact CG2-CG 4.42Å; I220-R224 WeakPolarHBondContact O-CB 3.29Å; I220-R224 WeakPolarHBondContact O-CG 3.5Å; I220-R224 PolarHBondContact O-N 3.26Å
221L96.8Very high95Very high0 Ų046.3 Ų46.30%025%0.247CC..Hα-helixtrans-58.2-49.7179.8-72.5173.2000111.9V185 L189 I195 P205 L206 A209 T217 A218 S223 R224 G225 A226V185-L221 HydrophobicContact CG1-CD2 4.34Å; L189-L221 HydrophobicContact CD1-CD2 4.27Å; I195-L221 HydrophobicContact CD1-CD2 4.02Å; I195-L221 WeakPolarHBondContact CD1-O 3.26Å; I195-L221 HydrophobicContact CG1-CD2 3.62Å; P205-L221 HydrophobicContact CB-CD1 4.25Å; P205-L221 HydrophobicContact CB-CD2 4.3Å; L206-L221 HydrophobicContact CB-CD1 4.1Å; L206-L221 HydrophobicContact CD1-CB 4.27Å; L206-L221 HydrophobicContact CD1-CD1 4.18Å; A209-L221 HydrophobicContact CB-CD1 4.19Å; T217-L221 VanDerWaalsContact O-CG 3.3Å; T217-L221 WeakPolarHBondContact O-CG 3.34Å; T217-L221 PolarHBondContact O-N 3.49Å; A218-L221 PolarHBondContact O-N 3.06Å; L221-S223 PolarHBondContact O-N 2.94Å; L221-R224 CarbonylContact O-C 3.47Å; L221-R224 PolarHBondContact O-N 3.01Å; L221-R224 VanDerWaalsContact O-N 3.15Å; L221-G225 PolarHBondContact O-N 2.85Å; L221-A226 VanDerWaalsContact C-CB 3.5Å; L221-A226 HydrophobicContact CB-CB 3.84Å; L221-A226 WeakPolarHBondContact O-CB 3.39Å; L221-A226 PolarHBondContact O-N 3.47Å
222L95.7Very high94.8Very high12 Ų1252.3 Ų52.36%0.06327%0.27CS..Hα-helixtrans-62.3-43.1178.7-67.7166000111.5L206 A218 I220 R224 G225 I252 L253 H256L206-L222 HydrophobicContact CD1-CD2 4.33Å; L206-L222 HydrophobicContact CD1-CG 4.16Å; L206-L222 HydrophobicContact CD2-CD2 3.82Å; A218-L222 VanDerWaalsContact O-CG 3.3Å; A218-L222 WeakPolarHBondContact O-CG 3.24Å; A218-L222 PolarHBondContact O-N 3.43Å; I220-L222 PolarHBondContact O-N 3.18Å; L222-R224 PolarHBondContact O-N 3.3Å; L222-G225 PolarHBondContact O-N 3.46Å; L222-I252 HydrophobicContact CD1-CG2 3.59Å; L222-L253 HydrophobicContact CD1-CD2 4Å; L222-L253 HydrophobicContact CD2-CD2 4.49Å; L222-H256 HydrophobicContact CD1-CB 4.29Å
223S95Very high94.6Very high74 Ų7455.2 Ų55.252%0.51729%0.288SS..Hα-helixtrans-63.2-26.8176.9750000113.6Q219 I220 L221Q219-S223 VanDerWaalsContact O-CB 3.29Å; Q219-S223 WeakPolarHBondContact O-CB 3.45Å; Q219-S223 PolarHBondContact O-N 3.28Å; Q219-S223 PolarHBondContact O-OG 3.32Å; I220-S223 WeakPolarHBondContact CA-OG 3.42Å; I220-S223 PolarHBondContact O-N 3.37Å; I220-S223 PolarHBondContact O-OG 2.78Å; L221-S223 PolarHBondContact O-N 2.94Å
224R94.8Very high94.4Very high112 Ų11256.5 Ų56.542%0.42330%0.302SS..THydrogen-bonded Turntrans-92.48.8176.6-66.3-68.9-16895.6-2.5113L189 D190 I195 I220 L221 L222L189-R224 HydrophobicContact CD1-CB 4.4Å; L189-R224 HydrophobicContact CD1-CG 4.18Å; D190-R224 IonicContact OD1-CZ 2.77Å; D190-R224 VanDerWaalsContact OD1-CZ 3.25Å; D190-R224 IonicContact OD1-NH1 2.98Å; D190-R224 PolarHBondContact OD1-NH1 3.28Å; D190-R224 IonicContact OD1-NH2 2.72Å; D190-R224 PolarHBondContact OD1-NH2 3.5Å; D190-R224 IonicContact OD2-NH2 2.95Å; I195-R224 HydrophobicContact CD1-CB 3.6Å; I220-R224 HydrophobicContact CG2-CG 4.42Å; I220-R224 WeakPolarHBondContact O-CB 3.29Å; I220-R224 WeakPolarHBondContact O-CG 3.5Å; I220-R224 PolarHBondContact O-N 3.26Å; L221-R224 CarbonylContact O-C 3.47Å; L221-R224 PolarHBondContact O-N 3.01Å; L221-R224 VanDerWaalsContact O-N 3.15Å; L222-R224 PolarHBondContact O-N 3.3Å
225G92.6Very high94.2Very high48 Ų4856.1 Ų56.150%0.49530%0.301SS..THydrogen-bonded Turntrans87.625.7173.300000115.3L221 L222 K227L221-G225 PolarHBondContact O-N 2.85Å; L222-G225 PolarHBondContact O-N 3.46Å; G225-K227 PolarHBondContact O-N 2.73Å
226A94.7Very high94.1Very high9 Ų953.1 Ų53.17%0.07429%0.292CS..  trans-59.2135.3169.900000110.8I195 L206 L221I195-A226 HydrophobicContact CD1-CB 3.87Å; I195-A226 HydrophobicContact CG1-CB 3.92Å; L206-A226 HydrophobicContact CD2-CB 4.42Å; L221-A226 VanDerWaalsContact C-CB 3.5Å; L221-A226 HydrophobicContact CB-CB 3.84Å; L221-A226 WeakPolarHBondContact O-CB 3.39Å; L221-A226 PolarHBondContact O-N 3.47Å
227K93.8Very high94Very high130 Ų13050.7 Ų50.757%0.56528%0.279SS*.  trans-83.3137.9177.9-65.1178-177.8175.80109.8N196 G225 L229N196-K227 WeakPolarHBondContact OD1-CB 3.33Å; N196-K227 PolarHBondContact OD1-N 3.16Å; G225-K227 PolarHBondContact O-N 2.73Å; K227-L229 HydrophobicContact CB-CD1 4.06Å; K227-L229 HydrophobicContact CB-CD2 4.34Å; K227-L229 HydrophobicContact CB-CG 3.84Å; K227-L229 PolarHBondContact O-N 2.99Å; K227-L229 VanDerWaalsContact O-N 3.13Å
228Y92.8Very high93.9Very high55 Ų5550.6 Ų50.622%0.21628%0.278CS..  trans-74.697.4168.8-173.2-92.2000109.7T236 P237 L238 L253 L260Y228-T236 HydrophobicContact CE1-CG2 4.3Å; Y228-T236 WeakPolarHBondContact OH-CB 3.28Å; Y228-T236 PolarHBondContact OH-OG1 2.82Å; Y228-P237 HydrophobicContact CD2-CB 4.34Å; Y228-P237 HydrophobicContact CD2-CG 4.1Å; Y228-P237 HydrophobicContact CE2-CB 3.93Å; Y228-P237 HydrophobicContact CE2-CG 3.98Å; Y228-L238 HydrophobicContact CE2-CB 4.45Å; Y228-L238 WeakPolarHBondContact OH-CB 3.44Å; Y228-L238 PolarHBondContact OH-N 2.62Å; Y228-L253 HydrophobicContact CD2-CD2 4.35Å; Y228-L253 HydrophobicContact CE2-CD2 4.4Å; Y228-L260 HydrophobicContact CD2-CD1 4.11Å; Y228-L260 HydrophobicContact CE1-CD2 3.96Å; Y228-L260 HydrophobicContact CE2-CD1 3.68Å; Y228-L260 HydrophobicContact CE2-CD2 4.11Å
229L92.6Very high93.7Very high75 Ų7552.4 Ų52.439%0.39329%0.288SS..  trans-123.2143.3-177.9-62.4176.2000110.6T204 K227 P237T204-L229 HydrophobicContact CG2-CB 4.32Å; T204-L229 HydrophobicContact CG2-CD1 4.24Å; K227-L229 HydrophobicContact CB-CD1 4.06Å; K227-L229 HydrophobicContact CB-CD2 4.34Å; K227-L229 HydrophobicContact CB-CG 3.84Å; K227-L229 PolarHBondContact O-N 2.99Å; K227-L229 VanDerWaalsContact O-N 3.13Å; L229-P237 VanDerWaalsContact O-CD 3.3Å; L229-P237 WeakPolarHBondContact O-CD 3.44Å
230A91.9Very high93.6Very high43 Ų4350.2 Ų50.236%0.35528%0.278SS..  trans-84.6158.7171.700000111.2I235 T236A230-I235 VanDerWaalsContact CA-O 3.3Å; A230-I235 WeakPolarHBondContact CA-O 3.5Å; A230-T236 HydrophobicContact CB-CG2 4.1Å
231D92.7Very high93.4Very high14 Ų1449 Ų498%0.07527%0.272CS..  trans-73.8-178.3169.974.16000112.4Y207 N233 G234 I235Y207-D231 HydrophobicContact CD2-CB 4.21Å; Y207-D231 HydrophobicContact CE2-CB 3.67Å; Y207-D231 PolarHBondContact OH-OD2 2.93Å; D231-N233 PolarHBondContact O-N 2.99Å; D231-N233 WeakPolarHBondContact OD1-CA 3.48Å; D231-N233 WeakPolarHBondContact OD1-CB 3.5Å; D231-N233 PolarHBondContact OD1-N 3.07Å; D231-G234 PolarHBondContact O-N 3.37Å; D231-G234 PolarHBondContact OD1-N 3.31Å; D231-I235 PolarHBondContact N-O 3.25Å; D231-I235 PolarHBondContact OD1-N 3.23Å
232K92.6Very high93.2Very high153 Ų15349 Ų4967%0.66527%0.272SS*.THydrogen-bonded Turntrans-62.4-20.9178.2-74.3177.5-179.8-179.60114.1V200 S201 G234V200-K232 VanDerWaalsContact O-CE 3.28Å; V200-K232 WeakPolarHBondContact O-CE 3.45Å; V200-K232 PolarHBondContact O-NZ 2.88Å; S201-K232 VanDerWaalsContact O-CB 3.32Å; S201-K232 WeakPolarHBondContact O-CB 3.25Å; S201-K232 VanDerWaalsContact O-CG 3.25Å; S201-K232 WeakPolarHBondContact O-CG 3.32Å; S201-K232 PolarHBondContact O-N 2.82Å; K232-G234 VanDerWaalsContact C-N 3.34Å
233N90.9Very high93Very high136 Ų13653.4 Ų53.473%0.72729%0.292SS*.THydrogen-bonded Turntrans-91.2-0.4177.7-61.2-31000112.2D231 I235D231-N233 PolarHBondContact O-N 2.99Å; D231-N233 WeakPolarHBondContact OD1-CA 3.48Å; D231-N233 WeakPolarHBondContact OD1-CB 3.5Å; D231-N233 PolarHBondContact OD1-N 3.07Å; N233-I235 VanDerWaalsContact C-N 3.33Å; N233-I235 HydrophobicContact CB-CD1 4.39Å; N233-I235 HydrophobicContact CB-CG1 4.24Å
234G91.2Very high92.7Very high48 Ų4851.2 Ų51.250%0.49528%0.281SS..  trans81.39.6-17700000114.1D231 K232 T236D231-G234 PolarHBondContact O-N 3.37Å; D231-G234 PolarHBondContact OD1-N 3.31Å; K232-G234 VanDerWaalsContact C-N 3.34Å; G234-T236 PolarHBondContact O-N 3.44Å
235I92.1Very high92.6Very high49 Ų4946.5 Ų46.525%0.25127%0.268SS..  trans-76.4123177.5-56.7176.1000108.7Y207 A230 D231 N233 D239 L240Y207-I235 HydrophobicContact CE2-CB 4.49Å; Y207-I235 HydrophobicContact CE2-CG2 4.42Å; A230-I235 VanDerWaalsContact CA-O 3.3Å; A230-I235 WeakPolarHBondContact CA-O 3.5Å; D231-I235 PolarHBondContact N-O 3.25Å; D231-I235 PolarHBondContact OD1-N 3.23Å; N233-I235 VanDerWaalsContact C-N 3.33Å; N233-I235 HydrophobicContact CB-CD1 4.39Å; N233-I235 HydrophobicContact CB-CG1 4.24Å; I235-D239 HydrophobicContact CG2-CB 3.92Å; I235-L240 HydrophobicContact CG2-CD2 3.78Å; I235-L240 HydrophobicContact CG2-CG 3.96Å
236T93.1Very high92.7Very high19 Ų1948.1 Ų48.112%0.11726%0.259CS..  trans-92.5159.7-178.273.20000112.2Y228 A230 G234 L238 D239 L240Y228-T236 HydrophobicContact CE1-CG2 4.3Å; Y228-T236 WeakPolarHBondContact OH-CB 3.28Å; Y228-T236 PolarHBondContact OH-OG1 2.82Å; A230-T236 HydrophobicContact CB-CG2 4.1Å; G234-T236 PolarHBondContact O-N 3.44Å; T236-L238 PolarHBondContact O-N 3.18Å; T236-D239 WeakPolarHBondContact CA-OD2 3.41Å; T236-D239 VanDerWaalsContact CB-OD2 3.27Å; T236-D239 WeakPolarHBondContact CB-OD2 3.39Å; T236-D239 WeakPolarHBondContact CG2-OD2 3.3Å; T236-D239 PolarHBondContact N-OD2 3.09Å; T236-D239 WeakPolarHBondContact O-CB 3.3Å; T236-D239 PolarHBondContact O-N 2.85Å; T236-D239 VanDerWaalsContact OG1-CG 3.23Å; T236-D239 PolarHBondContact OG1-N 3.04Å; T236-D239 PolarHBondContact OG1-OD2 3.02Å; T236-L240 PolarHBondContact O-N 3.21Å
237P94.3Very high92.6Very high0 Ų048 Ų480%026%0.259CS..Hα-helixtrans-57.5-29.6174.5-26.334.5000113.8L206 C210 Y228 L229 C241 L253L206-P237 HydrophobicContact CD2-CG 4.47Å; C210-P237 HydrophobicContact CB-CB 3.96Å; C210-P237 WeakPolarHBondContact CB-O 3.49Å; Y228-P237 HydrophobicContact CD2-CB 4.34Å; Y228-P237 HydrophobicContact CD2-CG 4.1Å; Y228-P237 HydrophobicContact CE2-CB 3.93Å; Y228-P237 HydrophobicContact CE2-CG 3.98Å; L229-P237 VanDerWaalsContact O-CD 3.3Å; L229-P237 WeakPolarHBondContact O-CD 3.44Å; P237-C241 PolarHBondContact O-N 2.96Å; P237-C241 PolarHBondContact O-SG 3.46Å; P237-L253 HydrophobicContact CB-CD1 4.37Å
238L94.4Very high92.5Very high0 Ų046.5 Ų46.50%025%0.254CS..Hα-helixtrans-68.9-42.7173.7-176.865.7000111.6Y228 T236 L240 C241 V242 C250 L253 L260 M263 M267Y228-L238 HydrophobicContact CE2-CB 4.45Å; Y228-L238 WeakPolarHBondContact OH-CB 3.44Å; Y228-L238 PolarHBondContact OH-N 2.62Å; T236-L238 PolarHBondContact O-N 3.18Å; L238-L240 VanDerWaalsContact C-N 3.27Å; L238-L240 PolarHBondContact O-N 3.02Å; L238-C241 PolarHBondContact O-N 3.37Å; L238-V242 HydrophobicContact CD1-CG2 4.28Å; L238-V242 HydrophobicContact CG-CG2 4.36Å; L238-V242 WeakPolarHBondContact O-CG2 3.19Å; L238-V242 PolarHBondContact O-N 3.4Å; L238-C250 HydrophobicContact CD1-CB 4.46Å; L238-L253 HydrophobicContact CB-CD1 4.48Å; L238-L253 HydrophobicContact CD1-CD1 4.46Å; L238-L260 HydrophobicContact CD2-CB 4.11Å; L238-L260 HydrophobicContact CD2-CD2 4.31Å; L238-M263 HydrophobicContact CD2-CB 3.97Å; L238-M267 HydrophobicContact CB-CE 4.32Å; L238-M267 HydrophobicContact CD2-CE 3.63Å; L238-M267 HydrophobicContact CD2-SD 4.41Å; L238-M267 HydrophobicContact CG-CE 3.81Å; L238-M267 HydrophobicContact CG-SD 4.38Å
239D93.3Very high92.5Very high37 Ų3744 Ų4420%0.19824%0.244CC..Hα-helixtrans-56.9-43.8178.6-62.6-52.7000111I235 T236 V242 Q243 M267I235-D239 HydrophobicContact CG2-CB 3.92Å; T236-D239 WeakPolarHBondContact CA-OD2 3.41Å; T236-D239 VanDerWaalsContact CB-OD2 3.27Å; T236-D239 WeakPolarHBondContact CB-OD2 3.39Å; T236-D239 WeakPolarHBondContact CG2-OD2 3.3Å; T236-D239 PolarHBondContact N-OD2 3.09Å; T236-D239 WeakPolarHBondContact O-CB 3.3Å; T236-D239 PolarHBondContact O-N 2.85Å; T236-D239 VanDerWaalsContact OG1-CG 3.23Å; T236-D239 PolarHBondContact OG1-N 3.04Å; T236-D239 PolarHBondContact OG1-OD2 3.02Å; D239-V242 PolarHBondContact O-N 3.16Å; D239-Q243 WeakPolarHBondContact O-CB 3.49Å; D239-Q243 WeakPolarHBondContact O-CG 3.3Å; D239-Q243 PolarHBondContact O-N 3.03Å; D239-M267 WeakPolarHBondContact OD1-CE 3.47Å
240L93.2Very high92.6Very high15 Ų1540.4 Ų40.48%0.07923%0.225CC..Hα-helixtrans-63-45.3177.6-62.9169.5000112.3Y207 I235 T236 L238 V242 Q243 G244Y207-L240 HydrophobicContact CD1-CD1 3.62Å; Y207-L240 HydrophobicContact CD2-CD1 3.4Å; Y207-L240 HydrophobicContact CE1-CD1 3.6Å; Y207-L240 HydrophobicContact CE1-CD2 4.3Å; Y207-L240 HydrophobicContact CE2-CD1 3.38Å; Y207-L240 HydrophobicContact CE2-CD2 4.29Å; Y207-L240 HydrophobicContact CE2-CG 4.19Å; Y207-L240 HydrophobicContact CG-CD1 3.51Å; Y207-L240 VanDerWaalsContact CZ-CD1 3.49Å; I235-L240 HydrophobicContact CG2-CD2 3.78Å; I235-L240 HydrophobicContact CG2-CG 3.96Å; T236-L240 PolarHBondContact O-N 3.21Å; L238-L240 VanDerWaalsContact C-N 3.27Å; L238-L240 PolarHBondContact O-N 3.02Å; L240-V242 VanDerWaalsContact C-N 3.28Å; L240-V242 PolarHBondContact O-N 3.39Å; L240-Q243 PolarHBondContact O-N 2.77Å; L240-G244 PolarHBondContact O-N 3.44Å
241C93.8Very high92.6Very high0 Ų039.8 Ų39.80%022%0.215CC..Hα-helixtrans-62.2-40.6177.9-620000111.2C210 P237 L238 G245 Y246 C250C210-C241 WeakPolarHBondContact CB-SG 3.36Å; C210-C241 VanDerWaalsContact SG-SG 3.65Å; P237-C241 PolarHBondContact O-N 2.96Å; P237-C241 PolarHBondContact O-SG 3.46Å; L238-C241 PolarHBondContact O-N 3.37Å; C241-G245 PolarHBondContact O-N 3.43Å; C241-G245 VanDerWaalsContact O-N 3.08Å; C241-Y246 PolarHBondContact O-N 2.88Å; C241-C250 HydrophobicContact CB-CB 4.5Å; C241-C250 WeakPolarHBondContact CB-SG 3.48Å
242V92.7Very high92.6Very high0 Ų039.6 Ų39.60%021%0.214CC..Hα-helixtrans-69.9-42178.6173.80000111.6L238 D239 L240 G244 G245 L264 M267 V273 M277 L278L238-V242 HydrophobicContact CD1-CG2 4.28Å; L238-V242 HydrophobicContact CG-CG2 4.36Å; L238-V242 WeakPolarHBondContact O-CG2 3.19Å; L238-V242 PolarHBondContact O-N 3.4Å; D239-V242 PolarHBondContact O-N 3.16Å; L240-V242 VanDerWaalsContact C-N 3.28Å; L240-V242 PolarHBondContact O-N 3.39Å; V242-G244 VanDerWaalsContact C-N 3.3Å; V242-G244 PolarHBondContact O-N 2.95Å; V242-G245 PolarHBondContact O-N 2.67Å; V242-L264 HydrophobicContact CG2-CD1 3.59Å; V242-M267 HydrophobicContact CB-SD 4.21Å; V242-M267 HydrophobicContact CG1-SD 4.27Å; V242-M267 HydrophobicContact CG2-SD 3.87Å; V242-V273 HydrophobicContact CG1-CG1 3.68Å; V242-M277 WeakPolarHBondContact O-CB 3.46Å; V242-L278 HydrophobicContact CG1-CD2 3.49Å; V242-L278 VanDerWaalsContact CG1-CD2 3.49Å; V242-L278 HydrophobicContact CG1-CG 3.79Å
243Q91.3Very high92.6Very high105 Ų10532.3 Ų32.349%0.49118%0.183SC..Hα-helixtrans-64.5-34.5176.5-74.3173.28.700112.5D239 L240D239-Q243 WeakPolarHBondContact O-CB 3.49Å; D239-Q243 WeakPolarHBondContact O-CG 3.3Å; D239-Q243 PolarHBondContact O-N 3.03Å; L240-Q243 PolarHBondContact O-N 2.77Å
244G89.2Confident92.7Very high28 Ų2826.8 Ų26.829%0.28915%0.153SC..THydrogen-bonded Turntrans-85.4-5.6177.200000115.3L240 V242 Y246L240-G244 PolarHBondContact O-N 3.44Å; V242-G244 VanDerWaalsContact C-N 3.3Å; V242-G244 PolarHBondContact O-N 2.95Å; G244-Y246 VanDerWaalsContact C-N 3.28Å; G244-Y246 WeakPolarHBondContact O-CE1 3.41Å; G244-Y246 PolarHBondContact O-N 3.25Å
245G92.1Very high92.6Very high13 Ų1330 Ų3013%0.13416%0.155CC..THydrogen-bonded Turntrans70.719.9-176.400000114.2C241 V242 G247C241-G245 PolarHBondContact O-N 3.43Å; C241-G245 VanDerWaalsContact O-N 3.08Å; V242-G245 PolarHBondContact O-N 2.67Å; G245-G247 VanDerWaalsContact C-N 3.34Å; G245-G247 PolarHBondContact O-N 3.39Å
246Y94.4Very high92.5Very high82 Ų8231.2 Ų31.232%0.32216%0.159SC..  trans-81.973-173.1-55-48.1000112.4C210 S211 G213 C241 G244 E248 T249 C250C210-Y246 VanDerWaalsContact O-CD2 3.28Å; C210-Y246 WeakPolarHBondContact O-CD2 3.35Å; S211-Y246 WeakPolarHBondContact O-CE2 3.32Å; G213-Y246 VanDerWaalsContact CA-CD2 3.4Å; G213-Y246 VanDerWaalsContact N-CD2 3.31Å; G213-Y246 VanDerWaalsContact N-CE2 3.31Å; C241-Y246 PolarHBondContact O-N 2.88Å; G244-Y246 VanDerWaalsContact C-N 3.28Å; G244-Y246 WeakPolarHBondContact O-CE1 3.41Å; G244-Y246 PolarHBondContact O-N 3.25Å; Y246-E248 PolarHBondContact O-N 3.33Å; Y246-T249 PolarHBondContact O-N 3.35Å; Y246-C250 PolarHBondContact O-N 2.98Å; Y246-C250 PolarHBondContact O-SG 3.32Å; Y246-C250 VanDerWaalsContact O-SG 3.33Å
247G92.1Very high92.4Very high7 Ų733.6 Ų33.67%0.07217%0.169CC..Hα-helixtrans-53.6-47.2-176.900000114.3G245 T249 C250 E251 H284G245-G247 VanDerWaalsContact C-N 3.34Å; G245-G247 PolarHBondContact O-N 3.39Å; G247-T249 VanDerWaalsContact C-N 3.3Å; G247-T249 PolarHBondContact O-N 3.49Å; G247-C250 WeakPolarHBondContact O-CB 3.34Å; G247-C250 PolarHBondContact O-N 3.02Å; G247-E251 PolarHBondContact O-N 3.48Å; G247-H284 VanDerWaalsContact C-CD2 3.41Å
248E92.1Very high92Very high98 Ų9837.4 Ų37.446%0.45820%0.2SC..Hα-helixtrans-66.9-32.3-177.8-32.9-171.9156.900112.7R215 Y246 I252 H284R215-E248 HydrophobicContact CB-CB 4.41Å; R215-E248 VanDerWaalsContact CD-CB 3.48Å; R215-E248 VanDerWaalsContact CD-OE2 3.29Å; R215-E248 WeakPolarHBondContact CD-OE2 3.3Å; R215-E248 HydrophobicContact CG-CB 4.21Å; R215-E248 IonicContact NE-OE2 2.73Å; R215-E248 PolarHBondContact NE-OE2 2.9Å; Y246-E248 PolarHBondContact O-N 3.33Å; E248-I252 PolarHBondContact O-N 2.95Å; E248-H284 PolarHBondContact N-CD2 2.95Å
249T93.4Very high91.7Very high1 Ų148.1 Ų48.11%0.00624%0.241CC..Hα-helixtrans-76.7-35.7177.9-54.10000111.1G213 R215 A218 Y246 G247 E251 I252 L253G213-T249 PolarHBondContact O-OG1 3.3Å; R215-T249 WeakPolarHBondContact CA-OG1 3.41Å; R215-T249 PolarHBondContact N-OG1 3.27Å; A218-T249 HydrophobicContact CB-CG2 3.92Å; Y246-T249 PolarHBondContact O-N 3.35Å; G247-T249 VanDerWaalsContact C-N 3.3Å; G247-T249 PolarHBondContact O-N 3.49Å; T249-E251 VanDerWaalsContact C-N 3.28Å; T249-E251 PolarHBondContact O-N 3.31Å; T249-I252 PolarHBondContact O-N 3.08Å; T249-L253 PolarHBondContact O-N 3.41Å
250C93.8Very high91.6Very high0 Ų046.7 Ų46.70%023%0.233CC..Hα-helixtrans-58.2-43170.8-68.20000111.5L238 C241 Y246 G247 I252 L253 I254 V281L238-C250 HydrophobicContact CD1-CB 4.46Å; C241-C250 HydrophobicContact CB-CB 4.5Å; C241-C250 WeakPolarHBondContact CB-SG 3.48Å; Y246-C250 PolarHBondContact O-N 2.98Å; Y246-C250 PolarHBondContact O-SG 3.32Å; Y246-C250 VanDerWaalsContact O-SG 3.33Å; G247-C250 WeakPolarHBondContact O-CB 3.34Å; G247-C250 PolarHBondContact O-N 3.02Å; C250-I252 PolarHBondContact O-N 3.12Å; C250-L253 WeakPolarHBondContact O-CB 3.35Å; C250-L253 PolarHBondContact O-N 3.45Å; C250-I254 VanDerWaalsContact O-CG1 3.3Å; C250-I254 WeakPolarHBondContact O-CG1 3.29Å; C250-I254 PolarHBondContact O-N 2.84Å; C250-V281 HydrophobicContact CB-CG1 3.76Å; C250-V281 VanDerWaalsContact SG-CG1 3.51Å
251E91.6Very high91.6Very high30 Ų3046.2 Ų46.214%0.1423%0.23CC..Hα-helixtrans-58.2-49.7179.7-168.3-154.7167.600111.1G247 T249 L253 I254 Q255 H284 Q288G247-E251 PolarHBondContact O-N 3.48Å; T249-E251 VanDerWaalsContact C-N 3.28Å; T249-E251 PolarHBondContact O-N 3.31Å; E251-L253 VanDerWaalsContact C-N 3.3Å; E251-L253 PolarHBondContact O-N 3.25Å; E251-I254 PolarHBondContact O-N 3.15Å; E251-I254 VanDerWaalsContact O-N 3.08Å; E251-Q255 WeakPolarHBondContact O-CG 3.29Å; E251-Q255 PolarHBondContact O-N 3.18Å; E251-Q255 PolarHBondContact OE1-NE2 3.48Å; E251-H284 IonicContact OE2-NE2 3.66Å; E251-Q288 HydrophobicContact CG-CG 4.23Å; E251-Q288 WeakPolarHBondContact OE1-CG 3.44Å; E251-Q288 PolarHBondContact OE2-NE2 3.22Å
252I93.3Very high91.4Very high11 Ų1150.1 Ų50.16%0.05625%0.248CC..Hα-helixtrans-55.9-44.2176.5-70.8-47.9000111.7R215 Q219 L222 E248 T249 C250 I254 Q255 H256R215-I252 HydrophobicContact CG-CG1 3.64Å; Q219-I252 HydrophobicContact CB-CG1 4.5Å; Q219-I252 HydrophobicContact CB-CG2 4.05Å; L222-I252 HydrophobicContact CD1-CG2 3.59Å; E248-I252 PolarHBondContact O-N 2.95Å; T249-I252 PolarHBondContact O-N 3.08Å; C250-I252 PolarHBondContact O-N 3.12Å; I252-I254 PolarHBondContact O-N 3.18Å; I252-Q255 PolarHBondContact O-N 3.46Å; I252-H256 PolarHBondContact O-CD2 3.04Å; I252-H256 PolarHBondContact O-N 2.94Å
253L93.4Very high91.3Very high0 Ų053.4 Ų53.40%027%0.265CS..Hα-helixtrans-61.4-43.7176.2-69.8171.9000111.9L222 Y228 P237 L238 T249 C250 E251 H256 H257 L260L222-L253 HydrophobicContact CD1-CD2 4Å; L222-L253 HydrophobicContact CD2-CD2 4.49Å; Y228-L253 HydrophobicContact CD2-CD2 4.35Å; Y228-L253 HydrophobicContact CE2-CD2 4.4Å; P237-L253 HydrophobicContact CB-CD1 4.37Å; L238-L253 HydrophobicContact CB-CD1 4.48Å; L238-L253 HydrophobicContact CD1-CD1 4.46Å; T249-L253 PolarHBondContact O-N 3.41Å; C250-L253 WeakPolarHBondContact O-CB 3.35Å; C250-L253 PolarHBondContact O-N 3.45Å; E251-L253 VanDerWaalsContact C-N 3.3Å; E251-L253 PolarHBondContact O-N 3.25Å; L253-H256 PolarHBondContact O-N 3.24Å; L253-H257 PolarHBondContact O-N 2.96Å; L253-L260 HydrophobicContact CB-CD1 3.86Å
254I92Very high91.4Very high19 Ų1948.4 Ų48.410%0.09724%0.241CC..Hα-helixtrans-66.6-38.3-179.8-68.5164.9000111.5C250 E251 I252 H256 H257 A258 L260 F261 L264 V285C250-I254 VanDerWaalsContact O-CG1 3.3Å; C250-I254 WeakPolarHBondContact O-CG1 3.29Å; C250-I254 PolarHBondContact O-N 2.84Å; E251-I254 PolarHBondContact O-N 3.15Å; E251-I254 VanDerWaalsContact O-N 3.08Å; I252-I254 PolarHBondContact O-N 3.18Å; I254-H256 VanDerWaalsContact C-N 3.34Å; I254-H256 PolarHBondContact O-N 2.97Å; I254-H257 CarbonylContact O-C 3.02Å; I254-H257 PolarHBondContact O-N 3.41Å; I254-A258 PolarHBondContact O-N 2.92Å; I254-L260 HydrophobicContact CG1-CB 4.18Å; I254-F261 HydrophobicContact CG2-CB 3.99Å; I254-F261 HydrophobicContact CG2-CD2 4.39Å; I254-L264 HydrophobicContact CD1-CD2 3.77Å; I254-V285 HydrophobicContact CD1-CG2 4.35Å
255Q90.2Very high91.5Very high115 Ų11547 Ų4754%0.53723%0.228SC..Hα-helixtrans-61.3-41.1176.7-72.7179.44.800111.8E251 I252E251-Q255 WeakPolarHBondContact O-CG 3.29Å; E251-Q255 PolarHBondContact O-N 3.18Å; E251-Q255 PolarHBondContact OE1-NE2 3.48Å; I252-Q255 PolarHBondContact O-N 3.46Å
256H89.7Confident91.5Very high75 Ų7551.3 Ų51.335%0.34724%0.244SC..Hα-helixtrans-78.7-29.9176.9-80-91.6000113.3Q219 L222 I252 L253 I254Q219-H256 PolarHBondContact OE1-NE2 3.29Å; L222-H256 HydrophobicContact CD1-CB 4.29Å; I252-H256 PolarHBondContact O-CD2 3.04Å; I252-H256 PolarHBondContact O-N 2.94Å; L253-H256 PolarHBondContact O-N 3.24Å; I254-H256 VanDerWaalsContact C-N 3.34Å; I254-H256 PolarHBondContact O-N 2.97Å
257H89.8Confident91.3Very high70 Ų7048.2 Ų48.232%0.32423%0.233SC..  trans-133.386.9-178.1-61-55.9000111.7L253 I254 R259 L260L253-H257 PolarHBondContact O-N 2.96Å; I254-H257 CarbonylContact O-C 3.02Å; I254-H257 PolarHBondContact O-N 3.41Å; H257-R259 PolarHBondContact O-N 3.36Å; H257-L260 HydrophobicContact CB-CD1 3.66Å; H257-L260 HydrophobicContact CB-CG 3.65Å; H257-L260 VanDerWaalsContact O-CB 3.25Å; H257-L260 WeakPolarHBondContact O-CB 3.12Å; H257-L260 WeakPolarHBondContact O-CG 3.27Å; H257-L260 PolarHBondContact O-N 3.17Å
258A85.4Confident91.2Very high79 Ų7947.9 Ų47.965%0.65323%0.229SC*.THydrogen-bonded Turntrans-55.5-24.1-17600000115.4I254 L260 F261I254-A258 PolarHBondContact O-N 2.92Å; A258-L260 VanDerWaalsContact C-N 3.26Å; A258-L260 PolarHBondContact O-N 3.25Å; A258-F261 WeakPolarHBondContact O-CB 3.44Å; A258-F261 PolarHBondContact O-N 2.98Å
259R89.7Confident91.1Very high225 Ų22546.1 Ų46.185%0.84922%0.221SC*.Hα-helixtrans-66.7-26.2175.1-66.6-177.7-177.3169.60.7113H257 F261 Q262 M263H257-R259 PolarHBondContact O-N 3.36Å; R259-F261 PolarHBondContact O-N 2.65Å; R259-Q262 PolarHBondContact O-N 2.85Å; R259-Q262 VanDerWaalsContact O-N 3.14Å; R259-M263 PolarHBondContact O-N 3.42Å
260L91.6Very high90.8Very high7 Ų749.5 Ų49.54%0.03724%0.239CC..Hα-helixtrans-64.4-24.8178.2-64.1-174.1000112.2Y228 L238 L253 I254 H257 A258 Q262 M263 L264Y228-L260 HydrophobicContact CD2-CD1 4.11Å; Y228-L260 HydrophobicContact CE1-CD2 3.96Å; Y228-L260 HydrophobicContact CE2-CD1 3.68Å; Y228-L260 HydrophobicContact CE2-CD2 4.11Å; L238-L260 HydrophobicContact CD2-CB 4.11Å; L238-L260 HydrophobicContact CD2-CD2 4.31Å; L253-L260 HydrophobicContact CB-CD1 3.86Å; I254-L260 HydrophobicContact CG1-CB 4.18Å; H257-L260 HydrophobicContact CB-CD1 3.66Å; H257-L260 HydrophobicContact CB-CG 3.65Å; H257-L260 VanDerWaalsContact O-CB 3.25Å; H257-L260 WeakPolarHBondContact O-CB 3.12Å; H257-L260 WeakPolarHBondContact O-CG 3.27Å; H257-L260 PolarHBondContact O-N 3.17Å; A258-L260 VanDerWaalsContact C-N 3.26Å; A258-L260 PolarHBondContact O-N 3.25Å; L260-Q262 VanDerWaalsContact C-N 3.33Å; L260-Q262 PolarHBondContact O-N 3.48Å; L260-M263 HydrophobicContact CD2-SD 3.67Å; L260-M263 PolarHBondContact O-N 3.06Å; L260-L264 PolarHBondContact O-N 3.04Å
261F91.5Very high90.3Very high6 Ų653.7 Ų53.73%0.02626%0.258CS..Hα-helixtrans-57.7-46.8172.3-178.2-94.8000111.4I254 A258 R259 M263 L264 I265 K295 V296I254-F261 HydrophobicContact CG2-CB 3.99Å; I254-F261 HydrophobicContact CG2-CD2 4.39Å; A258-F261 WeakPolarHBondContact O-CB 3.44Å; A258-F261 PolarHBondContact O-N 2.98Å; R259-F261 PolarHBondContact O-N 2.65Å; F261-M263 VanDerWaalsContact C-N 3.3Å; F261-M263 PolarHBondContact O-N 3.29Å; F261-L264 WeakPolarHBondContact O-CB 3.32Å; F261-L264 PolarHBondContact O-N 2.99Å; F261-I265 HydrophobicContact CD1-CG1 4.33Å; F261-I265 HydrophobicContact CE1-CD1 4.46Å; F261-I265 HydrophobicContact CE1-CG1 3.93Å; F261-I265 HydrophobicContact CZ-CD1 4.21Å; F261-I265 HydrophobicContact CZ-CG1 4.16Å; F261-I265 WeakPolarHBondContact O-CG1 3.27Å; F261-I265 PolarHBondContact O-N 3.29Å; F261-I265 VanDerWaalsContact O-N 3.07Å; F261-K295 HydrophobicContact CE1-CD 4.06Å; F261-K295 HydrophobicContact CE1-CG 3.89Å; F261-K295 HydrophobicContact CE2-CD 4.46Å; F261-K295 HydrophobicContact CZ-CB 4.39Å; F261-K295 HydrophobicContact CZ-CD 4Å; F261-K295 HydrophobicContact CZ-CG 3.75Å; F261-V296 HydrophobicContact CE2-CG2 3.73Å; F261-V296 HydrophobicContact CZ-CG2 3.94Å
262Q90.7Very high90Very high81 Ų8159.3 Ų59.338%0.37929%0.29SS..Hα-helixtrans-66.5-35.9179.1-169.562.329.300111.5R259 L260 I265 Q266R259-Q262 PolarHBondContact O-N 2.85Å; R259-Q262 VanDerWaalsContact O-N 3.14Å; L260-Q262 VanDerWaalsContact C-N 3.33Å; L260-Q262 PolarHBondContact O-N 3.48Å; Q262-I265 PolarHBondContact O-N 3.18Å; Q262-Q266 WeakPolarHBondContact O-CB 3.39Å; Q262-Q266 VanDerWaalsContact O-CG 3.32Å; Q262-Q266 WeakPolarHBondContact O-CG 3.25Å; Q262-Q266 PolarHBondContact O-N 3.31Å
263M90.3Very high89.7Confident69 Ų6959.3 Ų59.334%0.3429%0.29SS..Hα-helixtrans-64.2-43.4174.9-66.9176.763.900111.4L238 R259 L260 F261 I265 Q266 M267L238-M263 HydrophobicContact CD2-CB 3.97Å; R259-M263 PolarHBondContact O-N 3.42Å; L260-M263 HydrophobicContact CD2-SD 3.67Å; L260-M263 PolarHBondContact O-N 3.06Å; F261-M263 VanDerWaalsContact C-N 3.3Å; F261-M263 PolarHBondContact O-N 3.29Å; M263-I265 VanDerWaalsContact C-N 3.33Å; M263-I265 PolarHBondContact O-N 3.04Å; M263-Q266 WeakPolarHBondContact O-CB 3.28Å; M263-Q266 PolarHBondContact O-N 2.98Å; M263-Q266 VanDerWaalsContact O-N 3.11Å; M263-M267 WeakPolarHBondContact O-CG 3.21Å; M263-M267 PolarHBondContact O-N 3.41Å
264L92.4Very high89.4Confident0 Ų066.7 Ų66.70%032%0.322CS..Hα-helixtrans-57.9-45.3174.8175.764.7000111.5V242 I254 L260 F261 Q266 M267 L278 V281 L282 V285V242-L264 HydrophobicContact CG2-CD1 3.59Å; I254-L264 HydrophobicContact CD1-CD2 3.77Å; L260-L264 PolarHBondContact O-N 3.04Å; F261-L264 WeakPolarHBondContact O-CB 3.32Å; F261-L264 PolarHBondContact O-N 2.99Å; L264-Q266 VanDerWaalsContact C-N 3.34Å; L264-Q266 PolarHBondContact O-N 3.19Å; L264-M267 WeakPolarHBondContact O-CB 3.34Å; L264-M267 PolarHBondContact O-N 2.75Å; L264-L278 HydrophobicContact CD1-CD2 4.16Å; L264-V281 HydrophobicContact CD1-CG1 3.92Å; L264-V281 HydrophobicContact CD2-CG1 4.12Å; L264-L282 HydrophobicContact CD2-CD2 3.78Å; L264-L282 HydrophobicContact CG-CD2 4.02Å; L264-V285 HydrophobicContact CD2-CG2 4.41Å
265I93Very high89.2Confident0 Ų067.1 Ų67.10%032%0.324CS..Hα-helixtrans-63.7-41.6175.6-60.2-58.6000110.5F261 Q262 M263 M267 T268 L282 L300 V303F261-I265 HydrophobicContact CD1-CG1 4.33Å; F261-I265 HydrophobicContact CE1-CD1 4.46Å; F261-I265 HydrophobicContact CE1-CG1 3.93Å; F261-I265 HydrophobicContact CZ-CD1 4.21Å; F261-I265 HydrophobicContact CZ-CG1 4.16Å; F261-I265 WeakPolarHBondContact O-CG1 3.27Å; F261-I265 PolarHBondContact O-N 3.29Å; F261-I265 VanDerWaalsContact O-N 3.07Å; Q262-I265 PolarHBondContact O-N 3.18Å; M263-I265 VanDerWaalsContact C-N 3.33Å; M263-I265 PolarHBondContact O-N 3.04Å; I265-M267 VanDerWaalsContact C-N 3.32Å; I265-M267 PolarHBondContact O-N 3.14Å; I265-T268 WeakPolarHBondContact O-CB 3.42Å; I265-T268 WeakPolarHBondContact O-CG2 3.3Å; I265-T268 PolarHBondContact O-N 2.89Å; I265-T268 PolarHBondContact O-OG1 3.15Å; I265-L282 HydrophobicContact CD1-CD2 4.09Å; I265-L300 HydrophobicContact CD1-CD2 4.13Å; I265-L300 HydrophobicContact CD1-CG 4.18Å; I265-L300 HydrophobicContact CG2-CD2 4.33Å; I265-V303 HydrophobicContact CG2-CG2 3.76Å
266Q91.2Very high89.1Confident102 Ų10266.8 Ų66.848%0.47733%0.326SS..Hα-helixtrans-63.8-33.6177.2-75175-700113.2Q262 M263 L264 T268 Q269Q262-Q266 WeakPolarHBondContact O-CB 3.39Å; Q262-Q266 VanDerWaalsContact O-CG 3.32Å; Q262-Q266 WeakPolarHBondContact O-CG 3.25Å; Q262-Q266 PolarHBondContact O-N 3.31Å; M263-Q266 WeakPolarHBondContact O-CB 3.28Å; M263-Q266 PolarHBondContact O-N 2.98Å; M263-Q266 VanDerWaalsContact O-N 3.11Å; L264-Q266 VanDerWaalsContact C-N 3.34Å; L264-Q266 PolarHBondContact O-N 3.19Å; Q266-T268 PolarHBondContact O-N 2.89Å; Q266-T268 VanDerWaalsContact O-N 3.16Å; Q266-Q269 WeakPolarHBondContact O-CB 3.41Å; Q266-Q269 PolarHBondContact O-N 3.34Å
267M90.8Very high89Confident18 Ų1865.6 Ų65.69%0.08932%0.321CS..Hα-helixtrans-61.1-21.3175.8-70.9175.2-170.800113.2L238 D239 V242 M263 L264 I265 Q269 N270 L278L238-M267 HydrophobicContact CB-CE 4.32Å; L238-M267 HydrophobicContact CD2-CE 3.63Å; L238-M267 HydrophobicContact CD2-SD 4.41Å; L238-M267 HydrophobicContact CG-CE 3.81Å; L238-M267 HydrophobicContact CG-SD 4.38Å; D239-M267 WeakPolarHBondContact OD1-CE 3.47Å; V242-M267 HydrophobicContact CB-SD 4.21Å; V242-M267 HydrophobicContact CG1-SD 4.27Å; V242-M267 HydrophobicContact CG2-SD 3.87Å; M263-M267 WeakPolarHBondContact O-CG 3.21Å; M263-M267 PolarHBondContact O-N 3.41Å; L264-M267 WeakPolarHBondContact O-CB 3.34Å; L264-M267 PolarHBondContact O-N 2.75Å; I265-M267 VanDerWaalsContact C-N 3.32Å; I265-M267 PolarHBondContact O-N 3.14Å; M267-Q269 PolarHBondContact O-N 3.4Å; M267-N270 PolarHBondContact O-N 3.19Å; M267-L278 HydrophobicContact CB-CD2 4.13Å
268T90.3Very high89.1Confident0 Ų062.3 Ų62.30%031%0.306CS..THydrogen-bonded Turntrans-62.2-21.9174.166.10000113.3I265 Q266 L278 L282 L300 R327 I331I265-T268 WeakPolarHBondContact O-CB 3.42Å; I265-T268 WeakPolarHBondContact O-CG2 3.3Å; I265-T268 PolarHBondContact O-N 2.89Å; I265-T268 PolarHBondContact O-OG1 3.15Å; Q266-T268 PolarHBondContact O-N 2.89Å; Q266-T268 VanDerWaalsContact O-N 3.16Å; T268-L278 HydrophobicContact CG2-CD2 4.35Å; T268-L282 HydrophobicContact CG2-CD1 3.86Å; T268-L300 HydrophobicContact CG2-CD2 3.8Å; T268-R327 WeakPolarHBondContact O-CD 3.4Å; T268-R327 PolarHBondContact O-NE 2.82Å; T268-R327 VanDerWaalsContact O-NE 3.14Å; T268-I331 HydrophobicContact CG2-CD1 4.08Å
269Q89.9Confident89.3Confident60 Ų6061.4 Ų61.428%0.2829%0.285SS..THydrogen-bonded Turntrans-82-19.3175.6-63.8174.493.500113.5Q266 M267 V303 N307 S324 I328Q266-Q269 WeakPolarHBondContact O-CB 3.41Å; Q266-Q269 PolarHBondContact O-N 3.34Å; M267-Q269 PolarHBondContact O-N 3.4Å; Q269-V303 HydrophobicContact CG-CG1 3.82Å; Q269-N307 PolarHBondContact OE1-ND2 3.2Å; Q269-N307 PolarHBondContact OE1-OD1 2.86Å; Q269-S324 WeakPolarHBondContact CA-OG 3.36Å; Q269-S324 WeakPolarHBondContact CB-OG 3.47Å; Q269-S324 WeakPolarHBondContact CG-OG 3.18Å; Q269-I328 HydrophobicContact CG-CD1 3.88Å
270N86.8Confident89.2Confident72 Ų7255.4 Ų55.439%0.38527%0.267SS..  trans-83.8120.4-174.3-173.2-6000110.9M267 D272 V273 R327M267-N270 PolarHBondContact O-N 3.19Å; N270-D272 VanDerWaalsContact C-N 3.34Å; N270-D272 PolarHBondContact O-N 3.01Å; N270-D272 PolarHBondContact OD1-N 3.19Å; N270-V273 HydrophobicContact CB-CG2 4.34Å; N270-R327 PolarHBondContact O-NH1 2.88Å; N270-R327 VanDerWaalsContact O-NH1 3.14Å; N270-R327 PolarHBondContact O-NH2 3.05Å
271E83.8Confident89.2Confident88 Ų8855 Ų5541%0.41127%0.265SS..THydrogen-bonded Turntrans-66.6-32.2-179.5-71.1-173.2-16700113.6V273 K323 R327E271-V273 PolarHBondContact O-N 3.26Å; E271-V273 VanDerWaalsContact O-N 3.17Å; E271-K323 WeakPolarHBondContact OE1-CB 3.4Å; E271-K323 WeakPolarHBondContact OE1-CD 3.07Å; E271-K323 IonicContact OE2-NZ 2.76Å; E271-R327 PolarHBondContact O-NH1 3.03Å
272D85.2Confident89.2Confident149 Ų14954.8 Ų54.880%0.79726%0.264SS*.THydrogen-bonded Turntrans-64.4-24.7-176.1-63.1-32.8000112.9N270N270-D272 VanDerWaalsContact C-N 3.34Å; N270-D272 PolarHBondContact O-N 3.01Å; N270-D272 PolarHBondContact OD1-N 3.19Å
273V85.9Confident89.2Confident11 Ų1153.6 Ų53.67%0.06726%0.258CS..SBendtrans-81.2136.6177-176.40000109V242 N270 E271 E275 L278 R327V242-V273 HydrophobicContact CG1-CG1 3.68Å; N270-V273 HydrophobicContact CB-CG2 4.34Å; E271-V273 PolarHBondContact O-N 3.26Å; E271-V273 VanDerWaalsContact O-N 3.17Å; V273-E275 PolarHBondContact O-N 3.32Å; V273-L278 HydrophobicContact CB-CD1 4.11Å; V273-L278 HydrophobicContact CG1-CD1 3.63Å; V273-L278 HydrophobicContact CG1-CG 3.76Å; V273-R327 PolarHBondContact O-NH1 3.04Å; V273-R327 PolarHBondContact O-NH2 2.81Å
274K87.7Confident89.2Confident154 Ų15452.4 Ų52.467%0.6725%0.252SS*.  trans-69.9127.5176.5-67.5-178.1179.3-179.90111.3N276 M277 L278K274-N276 VanDerWaalsContact C-N 3.31Å; K274-N276 PolarHBondContact O-N 3.13Å; K274-M277 HydrophobicContact CB-CG 3.99Å; K274-M277 PolarHBondContact O-N 2.82Å; K274-M277 VanDerWaalsContact O-N 3.13Å; K274-L278 PolarHBondContact O-N 3.29Å
275E88.2Confident89Confident29 Ų2952.6 Ų52.614%0.13625%0.253CS..Hα-helixtrans-57.4-41.1-177.6-167.7177.5140.200112.4V273 M277 L278 R279 R327 R330 I331V273-E275 PolarHBondContact O-N 3.32Å; E275-M277 VanDerWaalsContact C-N 3.3Å; E275-M277 PolarHBondContact O-N 3.36Å; E275-L278 PolarHBondContact O-N 2.94Å; E275-R279 WeakPolarHBondContact O-CG 3.19Å; E275-R279 PolarHBondContact O-N 2.89Å; E275-R279 IonicContact OE1-CZ 3.84Å; E275-R279 VanDerWaalsContact OE1-CZ 3.28Å; E275-R279 IonicContact OE1-NE 3.44Å; E275-R279 PolarHBondContact OE1-NE 3.18Å; E275-R279 IonicContact OE1-NH2 3.93Å; E275-R279 PolarHBondContact OE1-NH2 3.12Å; E275-R327 HydrophobicContact CG-CG 4.21Å; E275-R330 WeakPolarHBondContact OE1-CB 3.43Å; E275-R330 IonicContact OE1-NE 2.82Å; E275-R330 PolarHBondContact OE1-NE 3.4Å; E275-R330 VanDerWaalsContact OE1-NE 3.08Å; E275-R330 IonicContact OE2-CZ 2.73Å; E275-R330 IonicContact OE2-NE 3.25Å; E275-R330 PolarHBondContact OE2-NE 3.29Å; E275-R330 VanDerWaalsContact OE2-NE 3.13Å; E275-R330 IonicContact OE2-NH2 3.5Å; E275-R330 PolarHBondContact OE2-NH2 2.93Å; E275-I331 HydrophobicContact CG-CD1 4.14Å; E275-I331 HydrophobicContact CG-CG1 4.03Å
276N86.8Confident88.7Confident107 Ų10752.8 Ų52.857%0.57225%0.254SS*.Hα-helixtrans-61.4-35.5179.6-69.8-13.8000113.1K274 R279 Q280K274-N276 VanDerWaalsContact C-N 3.31Å; K274-N276 PolarHBondContact O-N 3.13Å; N276-R279 PolarHBondContact O-N 3.25Å; N276-Q280 WeakPolarHBondContact O-CG 3.27Å; N276-Q280 PolarHBondContact O-N 3.34Å; N276-Q280 VanDerWaalsContact O-N 3.08Å
277M88.4Confident88.5Confident51 Ų5153.3 Ų53.325%0.25126%0.257SS..Hα-helixtrans-72.5-40.3180-56.9-60.3178.300111.2V242 K274 E275 R279 Q280 V281V242-M277 WeakPolarHBondContact O-CB 3.46Å; K274-M277 HydrophobicContact CB-CG 3.99Å; K274-M277 PolarHBondContact O-N 2.82Å; K274-M277 VanDerWaalsContact O-N 3.13Å; E275-M277 VanDerWaalsContact C-N 3.3Å; E275-M277 PolarHBondContact O-N 3.36Å; M277-R279 VanDerWaalsContact C-N 3.34Å; M277-R279 PolarHBondContact O-N 3.15Å; M277-Q280 PolarHBondContact O-N 3Å; M277-V281 WeakPolarHBondContact O-CG2 3.15Å; M277-V281 PolarHBondContact O-N 2.71Å
278L90.5Very high88.2Confident0 Ų056.2 Ų56.20%027%0.27CS..Hα-helixtrans-61.8-41172-82.6160.6000112.2V242 L264 M267 T268 V273 K274 E275 V281 L282 I331V242-L278 HydrophobicContact CG1-CD2 3.49Å; V242-L278 VanDerWaalsContact CG1-CD2 3.49Å; V242-L278 HydrophobicContact CG1-CG 3.79Å; L264-L278 HydrophobicContact CD1-CD2 4.16Å; M267-L278 HydrophobicContact CB-CD2 4.13Å; T268-L278 HydrophobicContact CG2-CD2 4.35Å; V273-L278 HydrophobicContact CB-CD1 4.11Å; V273-L278 HydrophobicContact CG1-CD1 3.63Å; V273-L278 HydrophobicContact CG1-CG 3.76Å; K274-L278 PolarHBondContact O-N 3.29Å; E275-L278 PolarHBondContact O-N 2.94Å; L278-V281 PolarHBondContact O-N 3.35Å; L278-L282 WeakPolarHBondContact O-CB 3.47Å; L278-L282 WeakPolarHBondContact O-CG 3.3Å; L278-L282 PolarHBondContact O-N 3.29Å; L278-I331 HydrophobicContact CB-CD1 4.38Å
279R89.9Confident87.8Confident61 Ų6158.1 Ų58.123%0.2328%0.283CS..Hα-helixtrans-58.8-49.1175.4-72.3176.8-177.5-166.72.5111E275 N276 M277 V281 L282 E283 I331E275-R279 WeakPolarHBondContact O-CG 3.19Å; E275-R279 PolarHBondContact O-N 2.89Å; E275-R279 IonicContact OE1-CZ 3.84Å; E275-R279 VanDerWaalsContact OE1-CZ 3.28Å; E275-R279 IonicContact OE1-NE 3.44Å; E275-R279 PolarHBondContact OE1-NE 3.18Å; E275-R279 IonicContact OE1-NH2 3.93Å; E275-R279 PolarHBondContact OE1-NH2 3.12Å; N276-R279 PolarHBondContact O-N 3.25Å; M277-R279 VanDerWaalsContact C-N 3.34Å; M277-R279 PolarHBondContact O-N 3.15Å; R279-V281 PolarHBondContact O-N 2.68Å; R279-L282 PolarHBondContact O-N 3.43Å; R279-E283 WeakPolarHBondContact O-CB 3.35Å; R279-E283 PolarHBondContact O-N 3.03Å; R279-I331 HydrophobicContact CG-CG1 4.03Å
280Q88.6Confident87.4Confident98 Ų9860.2 Ų60.246%0.45830%0.297SS..Hα-helixtrans-59.2-44.2177.8-73.4175.7-3.400112.6N276 M277 H284N276-Q280 WeakPolarHBondContact O-CG 3.27Å; N276-Q280 PolarHBondContact O-N 3.34Å; N276-Q280 VanDerWaalsContact O-N 3.08Å; M277-Q280 PolarHBondContact O-N 3Å; Q280-H284 PolarHBondContact O-N 3.2Å; Q280-H284 VanDerWaalsContact O-N 3.11Å
281V91.8Very high87.4Confident0 Ų060.5 Ų60.50%030%0.304CS..Hα-helixtrans-65.5-48178.5170.80000111.3C250 L264 M277 L278 R279 H284 V285C250-V281 HydrophobicContact CB-CG1 3.76Å; C250-V281 VanDerWaalsContact SG-CG1 3.51Å; L264-V281 HydrophobicContact CD1-CG1 3.92Å; L264-V281 HydrophobicContact CD2-CG1 4.12Å; M277-V281 WeakPolarHBondContact O-CG2 3.15Å; M277-V281 PolarHBondContact O-N 2.71Å; L278-V281 PolarHBondContact O-N 3.35Å; R279-V281 PolarHBondContact O-N 2.68Å; V281-H284 PolarHBondContact O-N 3.35Å; V281-V285 HydrophobicContact CG1-CG2 4.42Å; V281-V285 WeakPolarHBondContact O-CG2 3.39Å; V281-V285 PolarHBondContact O-N 3.33Å
282L91.8Very high87.4Confident0 Ų059.7 Ų59.70%030%0.3CS..Hα-helixtrans-68.6-34.8-178.9-72.3168.1000112.4L264 I265 T268 L278 R279 S286 V296 L300 I331 V335L264-L282 HydrophobicContact CD2-CD2 3.78Å; L264-L282 HydrophobicContact CG-CD2 4.02Å; I265-L282 HydrophobicContact CD1-CD2 4.09Å; T268-L282 HydrophobicContact CG2-CD1 3.86Å; L278-L282 WeakPolarHBondContact O-CB 3.47Å; L278-L282 WeakPolarHBondContact O-CG 3.3Å; L278-L282 PolarHBondContact O-N 3.29Å; R279-L282 PolarHBondContact O-N 3.43Å; L282-S286 WeakPolarHBondContact O-CB 3.36Å; L282-S286 PolarHBondContact O-N 3.08Å; L282-S286 PolarHBondContact O-OG 3.34Å; L282-V296 HydrophobicContact CD2-CG1 3.98Å; L282-L300 HydrophobicContact CD1-CD2 4.48Å; L282-I331 HydrophobicContact CD1-CG2 3.48Å; L282-I331 VanDerWaalsContact CD1-CG2 3.48Å; L282-V335 HydrophobicContact CB-CG2 4.16Å
283E90.3Very high87.6Confident56 Ų5653.3 Ų53.326%0.26227%0.265SS..Hα-helixtrans-55.3-54.4169.6167169-163.900110R279 V285 S286 Q287 L338R279-E283 WeakPolarHBondContact O-CB 3.35Å; R279-E283 PolarHBondContact O-N 3.03Å; E283-V285 PolarHBondContact O-N 3.48Å; E283-S286 PolarHBondContact O-N 3.08Å; E283-S286 VanDerWaalsContact O-N 3.15Å; E283-S286 PolarHBondContact O-OG 3.03Å; E283-Q287 WeakPolarHBondContact O-CG 3.37Å; E283-Q287 PolarHBondContact O-N 3.33Å; E283-Q287 PolarHBondContact OE1-NE2 3.37Å; E283-Q287 VanDerWaalsContact OE1-NE2 3.16Å; E283-L338 HydrophobicContact CB-CD1 3.94Å; E283-L338 HydrophobicContact CG-CD1 3.63Å
284H89.3Confident87.7Confident44 Ų4456.2 Ų56.220%0.20428%0.278CS..Hα-helixtrans-62-45-178.9-168.977.1000112.6G247 E248 E251 Q280 V281 S286 Q287 Q288G247-H284 VanDerWaalsContact C-CD2 3.41Å; E248-H284 PolarHBondContact N-CD2 2.95Å; E251-H284 IonicContact OE2-NE2 3.66Å; Q280-H284 PolarHBondContact O-N 3.2Å; Q280-H284 VanDerWaalsContact O-N 3.11Å; V281-H284 PolarHBondContact O-N 3.35Å; H284-S286 VanDerWaalsContact C-N 3.26Å; H284-S286 PolarHBondContact O-N 3.2Å; H284-Q287 PolarHBondContact O-N 3.48Å; H284-Q288 PolarHBondContact NE2-NE2 3.29Å
285V88.3Confident87.8Confident4 Ų453.8 Ų53.82%0.02427%0.267CS..Hα-helixtrans-62-35.5177172.70000111.4I254 L264 V281 E283 H292 V296I254-V285 HydrophobicContact CD1-CG2 4.35Å; L264-V285 HydrophobicContact CD2-CG2 4.41Å; V281-V285 HydrophobicContact CG1-CG2 4.42Å; V281-V285 WeakPolarHBondContact O-CG2 3.39Å; V281-V285 PolarHBondContact O-N 3.33Å; E283-V285 PolarHBondContact O-N 3.48Å; V285-H292 WeakPolarHBondContact O-CB 3.36Å; V285-V296 HydrophobicContact CG1-CG2 4.08Å
286S87.7Confident88Confident4 Ų452.4 Ų52.43%0.02826%0.261CS..Hα-helixtrans-73.3-29.9179.676.40000113.4L282 E283 H284 Q288 Y293L282-S286 WeakPolarHBondContact O-CB 3.36Å; L282-S286 PolarHBondContact O-N 3.08Å; L282-S286 PolarHBondContact O-OG 3.34Å; E283-S286 PolarHBondContact O-N 3.08Å; E283-S286 VanDerWaalsContact O-N 3.15Å; E283-S286 PolarHBondContact O-OG 3.03Å; H284-S286 VanDerWaalsContact C-N 3.26Å; H284-S286 PolarHBondContact O-N 3.2Å; S286-Q288 VanDerWaalsContact C-N 3.28Å; S286-Q288 PolarHBondContact O-N 2.96Å; S286-Y293 WeakPolarHBondContact O-CB 3.4Å
287Q87.1Confident88.3Confident114 Ų11447.3 Ų47.353%0.53323%0.234SC..Hα-helixtrans-75.3-12.5-178.3-74.5172.41.400113.8E283 H284E283-Q287 WeakPolarHBondContact O-CG 3.37Å; E283-Q287 PolarHBondContact O-N 3.33Å; E283-Q287 PolarHBondContact OE1-NE2 3.37Å; E283-Q287 VanDerWaalsContact OE1-NE2 3.16Å; H284-Q287 PolarHBondContact O-N 3.48Å
288Q83.1Confident88.4Confident79 Ų7946.9 Ų46.937%0.36923%0.234SC..THydrogen-bonded Turntrans-67.5-39.4-176.8-63.2-58.6-26.600113.5E251 H284 S286E251-Q288 HydrophobicContact CG-CG 4.23Å; E251-Q288 WeakPolarHBondContact OE1-CG 3.44Å; E251-Q288 PolarHBondContact OE2-NE2 3.22Å; H284-Q288 PolarHBondContact NE2-NE2 3.29Å; S286-Q288 VanDerWaalsContact C-N 3.28Å; S286-Q288 PolarHBondContact O-N 2.96Å
289S83.4Confident88.6Confident39 Ų3947.6 Ų47.627%0.27324%0.239SC..  trans-161.9156.3174.370.20000111.9S291 H292 Y293S289-S291 PolarHBondContact O-N 3.4Å; S289-S291 VanDerWaalsContact O-N 3.13Å; S289-S291 PolarHBondContact OG-OG 3.44Å; S289-H292 PolarHBondContact O-N 3.18Å; S289-H292 PolarHBondContact OG-N 3.33Å; S289-H292 PolarHBondContact OG-ND1 3.47Å; S289-Y293 PolarHBondContact O-N 2.91Å
290D82.1Confident88.8Confident105 Ų10544.7 Ų44.756%0.56123%0.228SC*.Hα-helixtrans-56.4-31.7175-69-15.4000112.9Q294D290-Q294 WeakPolarHBondContact O-CG 3.43Å; D290-Q294 PolarHBondContact O-N 3.39Å
291S85Confident89Confident77 Ų7740 Ų4054%0.53821%0.206SC..Hα-helixtrans-69.9-39.6175.656.60000112.9S289 K295S289-S291 PolarHBondContact O-N 3.4Å; S289-S291 VanDerWaalsContact O-N 3.13Å; S289-S291 PolarHBondContact OG-OG 3.44Å; S291-K295 VanDerWaalsContact O-CB 3.26Å; S291-K295 WeakPolarHBondContact O-CB 3.48Å; S291-K295 PolarHBondContact O-N 3.28Å
292H85.5Confident89.1Confident72 Ų7244.7 Ų44.733%0.33323%0.228SC..Hα-helixtrans-68.8-42174.2-74.499.8000111V285 S289 Q294 K295 V296V285-H292 WeakPolarHBondContact O-CB 3.36Å; S289-H292 PolarHBondContact O-N 3.18Å; S289-H292 PolarHBondContact OG-N 3.33Å; S289-H292 PolarHBondContact OG-ND1 3.47Å; H292-Q294 PolarHBondContact O-N 3.21Å; H292-K295 PolarHBondContact O-N 2.99Å; H292-V296 WeakPolarHBondContact O-CB 3.3Å; H292-V296 WeakPolarHBondContact O-CG2 3.22Å; H292-V296 PolarHBondContact O-N 3.25Å
293Y89.1Confident89.2Confident14 Ų1445.4 Ų45.46%0.05523%0.232CC..Hα-helixtrans-53.3-53.3173.2175.3-99.7000112.2S286 S289 K295 V296 L297 V335 F336 G339S286-Y293 WeakPolarHBondContact O-CB 3.4Å; S289-Y293 PolarHBondContact O-N 2.91Å; Y293-K295 VanDerWaalsContact C-N 3.34Å; Y293-K295 PolarHBondContact O-N 2.8Å; Y293-V296 PolarHBondContact O-N 3.05Å; Y293-L297 HydrophobicContact CD1-CD1 4.12Å; Y293-L297 HydrophobicContact CD2-CD1 4.29Å; Y293-L297 HydrophobicContact CE1-CD1 3.52Å; Y293-L297 HydrophobicContact CE2-CD1 3.72Å; Y293-L297 HydrophobicContact CG-CD1 4.46Å; Y293-L297 PolarHBondContact O-N 3.43Å; Y293-L297 VanDerWaalsContact O-N 3.14Å; Y293-L297 WeakPolarHBondContact OH-CD1 3.39Å; Y293-V335 HydrophobicContact CD2-CG1 4.4Å; Y293-V335 HydrophobicContact CE2-CG1 4.28Å; Y293-V335 WeakPolarHBondContact CE2-O 3.45Å; Y293-F336 WeakPolarHBondContact OH-CA 3.44Å; Y293-F336 PolarHBondContact OH-O 3.15Å; Y293-G339 VanDerWaalsContact CE2-CA 3.43Å
294Q87.8Confident89.4Confident73 Ų7342.9 Ų42.934%0.34122%0.221SC..Hα-helixtrans-63.1-39.9178-73.6177.59.400112.5D290 H292 T298D290-Q294 WeakPolarHBondContact O-CG 3.43Å; D290-Q294 PolarHBondContact O-N 3.39Å; H292-Q294 PolarHBondContact O-N 3.21Å; Q294-T298 WeakPolarHBondContact O-CB 3.19Å; Q294-T298 PolarHBondContact O-N 3.42Å; Q294-T298 PolarHBondContact O-OG1 3.12Å
295K90.3Very high89.5Confident102 Ų10241.4 Ų41.444%0.44322%0.215SC..Hα-helixtrans-64.9-45.7179.6-170.6-178178.7-176.10111.8F261 S291 H292 Y293 T298 S299F261-K295 HydrophobicContact CE1-CD 4.06Å; F261-K295 HydrophobicContact CE1-CG 3.89Å; F261-K295 HydrophobicContact CE2-CD 4.46Å; F261-K295 HydrophobicContact CZ-CB 4.39Å; F261-K295 HydrophobicContact CZ-CD 4Å; F261-K295 HydrophobicContact CZ-CG 3.75Å; S291-K295 VanDerWaalsContact O-CB 3.26Å; S291-K295 WeakPolarHBondContact O-CB 3.48Å; S291-K295 PolarHBondContact O-N 3.28Å; H292-K295 PolarHBondContact O-N 2.99Å; Y293-K295 VanDerWaalsContact C-N 3.34Å; Y293-K295 PolarHBondContact O-N 2.8Å; K295-T298 PolarHBondContact O-N 3.46Å; K295-S299 WeakPolarHBondContact O-CB 3.35Å; K295-S299 PolarHBondContact O-N 3.05Å; K295-S299 PolarHBondContact O-OG 3.33Å
296V91.9Very high89.7Confident0 Ų044.7 Ų44.70%024%0.235CC..Hα-helixtrans-58.1-51.8176.41690000110.3F261 L282 V285 H292 Y293 T298 S299 L300 V335F261-V296 HydrophobicContact CE2-CG2 3.73Å; F261-V296 HydrophobicContact CZ-CG2 3.94Å; L282-V296 HydrophobicContact CD2-CG1 3.98Å; V285-V296 HydrophobicContact CG1-CG2 4.08Å; H292-V296 WeakPolarHBondContact O-CB 3.3Å; H292-V296 WeakPolarHBondContact O-CG2 3.22Å; H292-V296 PolarHBondContact O-N 3.25Å; Y293-V296 PolarHBondContact O-N 3.05Å; V296-T298 PolarHBondContact O-N 3.31Å; V296-S299 PolarHBondContact O-N 3.37Å; V296-L300 HydrophobicContact CG1-CD1 3.81Å; V296-L300 HydrophobicContact CG1-CG 4.39Å; V296-L300 WeakPolarHBondContact O-CB 3.36Å; V296-L300 VanDerWaalsContact O-CG 3.27Å; V296-L300 WeakPolarHBondContact O-CG 3.45Å; V296-L300 PolarHBondContact O-N 3.4Å; V296-V335 HydrophobicContact CG1-CG1 4.32Å
297L91.6Very high89.8Confident0 Ų044.5 Ų44.50%023%0.234CC..Hα-helixtrans-63.7-43-178.8-72.2173.5000112.8Y293 L300 A301 F332 V335 F336 V361Y293-L297 HydrophobicContact CD1-CD1 4.12Å; Y293-L297 HydrophobicContact CD2-CD1 4.29Å; Y293-L297 HydrophobicContact CE1-CD1 3.52Å; Y293-L297 HydrophobicContact CE2-CD1 3.72Å; Y293-L297 HydrophobicContact CG-CD1 4.46Å; Y293-L297 PolarHBondContact O-N 3.43Å; Y293-L297 VanDerWaalsContact O-N 3.14Å; Y293-L297 WeakPolarHBondContact OH-CD1 3.39Å; L297-L300 PolarHBondContact O-N 3.11Å; L297-A301 WeakPolarHBondContact O-CB 3.26Å; L297-A301 PolarHBondContact O-N 2.95Å; L297-F332 HydrophobicContact CB-CD2 4.33Å; L297-F332 HydrophobicContact CB-CE2 3.93Å; L297-F332 HydrophobicContact CD2-CD2 3.67Å; L297-F332 HydrophobicContact CD2-CE2 3.8Å; L297-F332 HydrophobicContact CD2-CG 4.22Å; L297-F332 HydrophobicContact CD2-CZ 4.42Å; L297-F332 WeakPolarHBondContact CD2-O 3.24Å; L297-F332 HydrophobicContact CG-CE2 4.45Å; L297-F332 WeakPolarHBondContact O-CD2 3.47Å; L297-F332 WeakPolarHBondContact O-CE2 3.24Å; L297-V335 HydrophobicContact CD2-CB 3.97Å; L297-V335 HydrophobicContact CD2-CG1 3.88Å; L297-V335 HydrophobicContact CG-CG1 4.17Å; L297-F336 HydrophobicContact CD1-CB 4.4Å; L297-F336 HydrophobicContact CD1-CD2 4.01Å; L297-F336 HydrophobicContact CD2-CB 4.04Å; L297-V361 HydrophobicContact CB-CB 3.86Å; L297-V361 HydrophobicContact CB-CG1 3.9Å; L297-V361 HydrophobicContact CB-CG2 4.26Å; L297-V361 HydrophobicContact CD1-CG1 4.31Å; L297-V361 HydrophobicContact CD1-CG2 4.26Å
298T92.3Very high89.9Confident43 Ų4339 Ų3926%0.26421%0.208SC..Hα-helixtrans-63.7-43.9178.9-53.30000111.1Q294 K295 V296 A301 E302 P364Q294-T298 WeakPolarHBondContact O-CB 3.19Å; Q294-T298 PolarHBondContact O-N 3.42Å; Q294-T298 PolarHBondContact O-OG1 3.12Å; K295-T298 PolarHBondContact O-N 3.46Å; V296-T298 PolarHBondContact O-N 3.31Å; T298-A301 WeakPolarHBondContact O-CB 3.35Å; T298-A301 PolarHBondContact O-N 3.25Å; T298-E302 WeakPolarHBondContact O-CG 3.32Å; T298-E302 PolarHBondContact O-N 3.08Å; T298-P364 HydrophobicContact CG2-CG 4.32Å
299S93.6Very high90.2Very high14 Ų1438.6 Ų38.610%0.09821%0.206CC..Hα-helixtrans-67.6-37.2177.6-64.30000113K295 V296 E302 V303K295-S299 WeakPolarHBondContact O-CB 3.35Å; K295-S299 PolarHBondContact O-N 3.05Å; K295-S299 PolarHBondContact O-OG 3.33Å; V296-S299 PolarHBondContact O-N 3.37Å; S299-E302 PolarHBondContact O-N 2.87Å; S299-V303 WeakPolarHBondContact O-CG2 3.47Å; S299-V303 PolarHBondContact O-N 3.24Å; S299-V303 VanDerWaalsContact O-N 3.13Å
300L94.3Very high90.4Very high0 Ų041 Ų410%021%0.211CC..Hα-helixtrans-63.6-42.7172.3-71.7172000111.3I265 T268 L282 V296 L297 V303 A304 I328 I331 F332I265-L300 HydrophobicContact CD1-CD2 4.13Å; I265-L300 HydrophobicContact CD1-CG 4.18Å; I265-L300 HydrophobicContact CG2-CD2 4.33Å; T268-L300 HydrophobicContact CG2-CD2 3.8Å; L282-L300 HydrophobicContact CD1-CD2 4.48Å; V296-L300 HydrophobicContact CG1-CD1 3.81Å; V296-L300 HydrophobicContact CG1-CG 4.39Å; V296-L300 WeakPolarHBondContact O-CB 3.36Å; V296-L300 VanDerWaalsContact O-CG 3.27Å; V296-L300 WeakPolarHBondContact O-CG 3.45Å; V296-L300 PolarHBondContact O-N 3.4Å; L297-L300 PolarHBondContact O-N 3.11Å; L300-V303 PolarHBondContact O-N 3.37Å; L300-A304 WeakPolarHBondContact O-CB 3.5Å; L300-A304 PolarHBondContact O-N 3.03Å; L300-I328 HydrophobicContact CB-CG2 4.34Å; L300-I328 HydrophobicContact CD2-CG2 4.22Å; L300-I328 WeakPolarHBondContact O-CG2 3.37Å; L300-I331 HydrophobicContact CD1-CG2 4.12Å; L300-F332 HydrophobicContact CB-CB 4.27Å; L300-F332 HydrophobicContact CB-CD2 4.03Å; L300-F332 HydrophobicContact CD1-CB 4.38Å
301A93Very high90.6Very high0 Ų036 Ų360%019%0.185CC..Hα-helixtrans-61.1-43.5176.100000111.9L297 T298 V303 A304 T305 F332 V361 P364 L365L297-A301 WeakPolarHBondContact O-CB 3.26Å; L297-A301 PolarHBondContact O-N 2.95Å; T298-A301 WeakPolarHBondContact O-CB 3.35Å; T298-A301 PolarHBondContact O-N 3.25Å; A301-V303 PolarHBondContact O-N 3.14Å; A301-A304 PolarHBondContact O-N 3.03Å; A301-T305 WeakPolarHBondContact O-CB 3.1Å; A301-T305 PolarHBondContact O-N 2.75Å; A301-T305 PolarHBondContact O-OG1 3.05Å; A301-F332 HydrophobicContact CB-CD2 4.35Å; A301-F332 HydrophobicContact CB-CE2 3.96Å; A301-V361 WeakPolarHBondContact CB-O 3.44Å; A301-P364 HydrophobicContact CB-CB 3.98Å; A301-P364 HydrophobicContact CB-CG 3.97Å; A301-L365 HydrophobicContact CB-CD1 4.22Å; A301-L365 HydrophobicContact CB-CG 3.97Å
302E94Very high90.5Very high98 Ų9833 Ų3346%0.45816%0.163SC..Hα-helixtrans-61.5-42.8176.5-73.3169.5175.100112.9T298 S299 T305 T306 P364T298-E302 WeakPolarHBondContact O-CG 3.32Å; T298-E302 PolarHBondContact O-N 3.08Å; S299-E302 PolarHBondContact O-N 2.87Å; E302-T305 PolarHBondContact O-N 3.5Å; E302-T306 PolarHBondContact O-N 3.2Å; E302-T306 PolarHBondContact O-OG1 3.46Å; E302-P364 HydrophobicContact CG-CB 4.03Å; E302-P364 HydrophobicContact CG-CG 3.96Å
303V93.8Very high90.3Very high16 Ų1631.9 Ų31.910%0.09716%0.163CC..Hα-helixtrans-69.3-40.9177.3178.70000111I265 Q269 S299 L300 A301 T306 N307 I328I265-V303 HydrophobicContact CG2-CG2 3.76Å; Q269-V303 HydrophobicContact CG-CG1 3.82Å; S299-V303 WeakPolarHBondContact O-CG2 3.47Å; S299-V303 PolarHBondContact O-N 3.24Å; S299-V303 VanDerWaalsContact O-N 3.13Å; L300-V303 PolarHBondContact O-N 3.37Å; A301-V303 PolarHBondContact O-N 3.14Å; V303-T306 PolarHBondContact O-N 3.45Å; V303-N307 PolarHBondContact O-N 3.17Å; V303-I328 HydrophobicContact CG1-CD1 3.7Å
304A93.6Very high89.5Confident2 Ų234.7 Ų34.72%0.01718%0.179CC..Hα-helixtrans-59.7-45.5173.200000111.7L300 A301 T306 N307 G308 L325 I328 V329 L365L300-A304 WeakPolarHBondContact O-CB 3.5Å; L300-A304 PolarHBondContact O-N 3.03Å; A301-A304 PolarHBondContact O-N 3.03Å; A304-T306 VanDerWaalsContact C-N 3.34Å; A304-T306 PolarHBondContact O-N 3.25Å; A304-N307 PolarHBondContact O-N 3.05Å; A304-G308 PolarHBondContact O-N 2.6Å; A304-L325 HydrophobicContact CB-CD1 4.13Å; A304-L325 VanDerWaalsContact O-CD1 3.25Å; A304-L325 WeakPolarHBondContact O-CD1 3.4Å; A304-I328 HydrophobicContact CB-CB 4.42Å; A304-I328 HydrophobicContact CB-CG2 3.83Å; A304-V329 HydrophobicContact CB-CG2 4.05Å; A304-L365 HydrophobicContact CB-CD2 3.8Å
305T92.9Very high88.8Confident13 Ų1336.5 Ų36.58%0.0820%0.199CC..Hα-helixtrans-57.7-46.8175-63.60000111.4A301 E302 N307 G308 H309 P364 L365 L368A301-T305 WeakPolarHBondContact O-CB 3.1Å; A301-T305 PolarHBondContact O-N 2.75Å; A301-T305 PolarHBondContact O-OG1 3.05Å; E302-T305 PolarHBondContact O-N 3.5Å; T305-N307 PolarHBondContact O-N 3.47Å; T305-G308 PolarHBondContact O-N 2.97Å; T305-H309 PolarHBondContact O-N 3.29Å; T305-H309 PolarHBondContact O-ND1 3.19Å; T305-P364 WeakPolarHBondContact CG2-O 3.44Å; T305-P364 PolarHBondContact OG1-O 3.02Å; T305-L365 WeakPolarHBondContact OG1-CA 3.29Å; T305-L365 PolarHBondContact OG1-N 3.09Å; T305-L368 HydrophobicContact CG2-CB 4.28Å
306T91.9Very high88.3Confident73 Ų7332.6 Ų32.645%0.44819%0.185SC..Hα-helixtrans-60.7-45.6179.5-56.10000112E302 V303 A304 K310E302-T306 PolarHBondContact O-N 3.2Å; E302-T306 PolarHBondContact O-OG1 3.46Å; V303-T306 PolarHBondContact O-N 3.45Å; A304-T306 VanDerWaalsContact C-N 3.34Å; A304-T306 PolarHBondContact O-N 3.25Å; T306-K310 WeakPolarHBondContact O-CG 2.99Å; T306-K310 PolarHBondContact O-N 3.13Å; T306-K310 VanDerWaalsContact O-N 3.07Å
307N89.1Confident87.9Confident0 Ų035.7 Ų35.70%021%0.207CC..Hα-helixtrans-71.8-33.5178.1-73.1-20.3000112.4Q269 V303 A304 T305 K310 L311 Q321 S324 I328Q269-N307 PolarHBondContact OE1-ND2 3.2Å; Q269-N307 PolarHBondContact OE1-OD1 2.86Å; V303-N307 PolarHBondContact O-N 3.17Å; A304-N307 PolarHBondContact O-N 3.05Å; T305-N307 PolarHBondContact O-N 3.47Å; N307-K310 PolarHBondContact O-N 3.24Å; N307-K310 PolarHBondContact OD1-NZ 2.91Å; N307-L311 WeakPolarHBondContact O-CB 3.33Å; N307-L311 PolarHBondContact O-N 3.22Å; N307-Q321 PolarHBondContact OD1-OE1 3.38Å; N307-Q321 VanDerWaalsContact OD1-OE1 3.04Å; N307-S324 PolarHBondContact ND2-OG 3.42Å; N307-I328 WeakPolarHBondContact ND2-CD1 3.48Å
308G89.4Confident87.5Confident0 Ų038.4 Ų38.40%022%0.217CC..Hα-helixtrans-60.2-48.8171.500000112.2A304 T305 K310 L311 L312 L368A304-G308 PolarHBondContact O-N 2.6Å; T305-G308 PolarHBondContact O-N 2.97Å; G308-K310 VanDerWaalsContact C-N 3.35Å; G308-K310 PolarHBondContact O-N 3.33Å; G308-L311 WeakPolarHBondContact O-CA 3.4Å; G308-L311 WeakPolarHBondContact O-CB 3.12Å; G308-L311 PolarHBondContact O-N 2.94Å; G308-L312 WeakPolarHBondContact O-CG 3.48Å; G308-L312 PolarHBondContact O-N 3.41Å; G308-L368 VanDerWaalsContact C-CD1 3.49Å
309H89.3Confident87.1Confident69 Ų6940 Ų4032%0.31922%0.224SC..Hα-helixtrans-64.5-37.1176.4-74.7129.2000112.7T305 L311 L312 S313 S371T305-H309 PolarHBondContact O-N 3.29Å; T305-H309 PolarHBondContact O-ND1 3.19Å; H309-L311 VanDerWaalsContact C-N 3.28Å; H309-L311 PolarHBondContact O-N 2.83Å; H309-L312 PolarHBondContact O-N 3.43Å; H309-S313 PolarHBondContact O-N 3.17Å; H309-S313 VanDerWaalsContact O-N 3.14Å; H309-S371 PolarHBondContact NE2-OG 2.97Å
310K87.9Confident86.7Confident89 Ų8941.2 Ų41.239%0.38724%0.235SC..Hα-helixtrans-59.7-41.3170.2-73.6173.5-171.6165.70111.3T306 N307 G308 L312 S313 S316 Q321T306-K310 WeakPolarHBondContact O-CG 2.99Å; T306-K310 PolarHBondContact O-N 3.13Å; T306-K310 VanDerWaalsContact O-N 3.07Å; N307-K310 PolarHBondContact O-N 3.24Å; N307-K310 PolarHBondContact OD1-NZ 2.91Å; G308-K310 VanDerWaalsContact C-N 3.35Å; G308-K310 PolarHBondContact O-N 3.33Å; K310-L312 VanDerWaalsContact C-N 3.33Å; K310-L312 PolarHBondContact O-N 3.37Å; K310-S313 WeakPolarHBondContact O-CA 3.47Å; K310-S313 WeakPolarHBondContact O-CB 3.48Å; K310-S313 PolarHBondContact O-N 2.66Å; K310-S316 VanDerWaalsContact O-CB 3.31Å; K310-S316 WeakPolarHBondContact O-CB 3.48Å; K310-S316 PolarHBondContact O-OG 2.9Å; K310-Q321 HydrophobicContact CB-CG 4.3Å
311L85.8Confident86.4Confident0 Ų042.9 Ų42.90%024%0.243CC..Hα-helixtrans-66-36.1179.3-162.865.8000112.1N307 G308 H309 S313 Y318 Q321 M322 L325 R439 A442 V443N307-L311 WeakPolarHBondContact O-CB 3.33Å; N307-L311 PolarHBondContact O-N 3.22Å; G308-L311 WeakPolarHBondContact O-CA 3.4Å; G308-L311 WeakPolarHBondContact O-CB 3.12Å; G308-L311 PolarHBondContact O-N 2.94Å; H309-L311 VanDerWaalsContact C-N 3.28Å; H309-L311 PolarHBondContact O-N 2.83Å; L311-S313 PolarHBondContact O-N 3.28Å; L311-Y318 HydrophobicContact CD1-CD2 3.96Å; L311-Q321 HydrophobicContact CB-CB 4.4Å; L311-Q321 HydrophobicContact CD1-CB 3.69Å; L311-M322 HydrophobicContact CD1-CB 4.35Å; L311-L325 HydrophobicContact CD2-CD2 3.98Å; L311-R439 HydrophobicContact CD1-CG 4.24Å; L311-R439 HydrophobicContact CG-CB 4.17Å; L311-R439 HydrophobicContact CG-CG 4.37Å; L311-R439 WeakPolarHBondContact O-CB 3.38Å; L311-R439 WeakPolarHBondContact O-CD 3.42Å; L311-R439 PolarHBondContact O-NH1 3.38Å; L311-A442 HydrophobicContact CD2-CB 3.65Å; L311-V443 HydrophobicContact CB-CG2 4.37Å; L311-V443 HydrophobicContact CD2-CG2 3.87Å; L311-V443 HydrophobicContact CG-CG2 4.42Å
312L84.1Confident86.2Confident15 Ų1544.1 Ų44.18%0.07925%0.249CC..Hα-helixtrans-66.9-20.6171.5-62.9178.4000112.9G308 H309 K310 L368 L440 V443G308-L312 WeakPolarHBondContact O-CG 3.48Å; G308-L312 PolarHBondContact O-N 3.41Å; H309-L312 PolarHBondContact O-N 3.43Å; K310-L312 VanDerWaalsContact C-N 3.33Å; K310-L312 PolarHBondContact O-N 3.37Å; L312-L368 HydrophobicContact CD1-CD1 3.86Å; L312-L440 HydrophobicContact CD2-CD2 3.42Å; L312-L440 VanDerWaalsContact CD2-CD2 3.42Å; L312-V443 HydrophobicContact CD2-CG2 3.96Å; L312-V443 HydrophobicContact CG-CG2 4.32Å
313S81.3Confident86Confident49 Ų4943.2 Ų43.234%0.34324%0.243SC..SBendtrans-86.5133.9171.5-175.90000111.5H309 K310 L311 S315 S316 R439H309-S313 PolarHBondContact O-N 3.17Å; H309-S313 VanDerWaalsContact O-N 3.14Å; K310-S313 WeakPolarHBondContact O-CA 3.47Å; K310-S313 WeakPolarHBondContact O-CB 3.48Å; K310-S313 PolarHBondContact O-N 2.66Å; L311-S313 PolarHBondContact O-N 3.28Å; S313-S315 PolarHBondContact O-N 3.13Å; S313-S315 PolarHBondContact OG-N 3.47Å; S313-S315 PolarHBondContact OG-OG 3.33Å; S313-S316 PolarHBondContact O-OG 3.39Å; S313-R439 PolarHBondContact O-NH1 3.47Å
314L71.4Confident85.9Confident73 Ų7342.7 Ų42.738%0.38224%0.24SC..THydrogen-bonded Turntrans-67-13.6174.8-68.3179.7000114S316 L403 T436L314-S316 VanDerWaalsContact C-N 3.31Å; L314-S316 PolarHBondContact O-N 2.97Å; L314-L403 HydrophobicContact CD1-CB 3.84Å; L314-L403 HydrophobicContact CD1-CD1 3.97Å; L314-L403 HydrophobicContact CD1-CD2 3.94Å; L314-L403 HydrophobicContact CD1-CG 4.15Å; L314-L403 HydrophobicContact CG-CD2 4.01Å; L314-T436 HydrophobicContact CD2-CG2 3.79Å
315S72.9Confident85.9Confident110 Ų11042.6 Ų42.677%0.76924%0.24SC*.THydrogen-bonded Turntrans-78.1-11.5-176.563.90000114.6S313S313-S315 PolarHBondContact O-N 3.13Å; S313-S315 PolarHBondContact OG-N 3.47Å; S313-S315 PolarHBondContact OG-OG 3.33Å
316S80.1Confident85.8Confident20 Ų2042.6 Ų42.614%0.1424%0.239CC..SBendtrans-98.6153.8-175.271.30000112K310 S313 L314 Y318 R439K310-S316 VanDerWaalsContact O-CB 3.31Å; K310-S316 WeakPolarHBondContact O-CB 3.48Å; K310-S316 PolarHBondContact O-OG 2.9Å; S313-S316 PolarHBondContact O-OG 3.39Å; L314-S316 VanDerWaalsContact C-N 3.31Å; L314-S316 PolarHBondContact O-N 2.97Å; S316-Y318 PolarHBondContact O-N 2.87Å; S316-R439 PolarHBondContact O-NH1 3.3Å; S316-R439 PolarHBondContact O-NH2 2.76Å; S316-R439 PolarHBondContact OG-NH1 3.13Å; S316-R439 VanDerWaalsContact OG-NH1 3.08Å
317S82.9Confident85.9Confident66 Ų6639.9 Ų39.946%0.46222%0.221SC..  trans-65.6121169.9174.70000110.4Q321S317-Q321 WeakPolarHBondContact O-CB 3.27Å; S317-Q321 VanDerWaalsContact O-CG 3.24Å; S317-Q321 WeakPolarHBondContact O-CG 3.28Å; S317-Q321 PolarHBondContact O-N 3.3Å
318Y83.4Confident86.1Confident57 Ų5739.9 Ų39.922%0.22422%0.221CC..Hα-helixtrans-59.4-53.4179.4162.5-110.1000111.8L311 S316 A320 Q321 M322 N438 R439 H489L311-Y318 HydrophobicContact CD1-CD2 3.96Å; S316-Y318 PolarHBondContact O-N 2.87Å; Y318-A320 PolarHBondContact O-N 2.94Å; Y318-Q321 PolarHBondContact O-N 2.91Å; Y318-M322 HydrophobicContact CD2-CB 4.36Å; Y318-M322 HydrophobicContact CE1-SD 4.11Å; Y318-M322 HydrophobicContact CE2-CB 4.09Å; Y318-M322 HydrophobicContact CE2-CG 4.32Å; Y318-M322 HydrophobicContact CE2-SD 3.93Å; Y318-M322 WeakPolarHBondContact O-CB 3.25Å; Y318-M322 PolarHBondContact O-N 3.14Å; Y318-M322 PolarHBondContact OH-SD 3.01Å; Y318-N438 HydrophobicContact CE1-CB 4.3Å; Y318-N438 HydrophobicContact CE2-CB 3.79Å; Y318-N438 WeakPolarHBondContact CE2-O 3.39Å; Y318-R439 HydrophobicContact CD2-CB 4.45Å; Y318-R439 HydrophobicContact CD2-CG 3.62Å; Y318-R439 HydrophobicContact CE2-CG 4.39Å; Y318-R439 HydrophobicContact CG-CG 4.37Å; Y318-H489 PolarHBondContact OH-NE2 3.35Å
319D83.8Confident86.3Confident75 Ų7540 Ų4040%0.40122%0.221SC..Hα-helixtrans-61.1-49.6-171.4-17463.1000112M322 K323D319-M322 PolarHBondContact O-N 3.47Å; D319-K323 WeakPolarHBondContact O-CB 3.39Å; D319-K323 WeakPolarHBondContact O-CG 3.45Å; D319-K323 PolarHBondContact O-N 3.43Å; D319-K323 WeakPolarHBondContact OD1-CE 3.37Å; D319-K323 IonicContact OD1-NZ 2.84Å; D319-K323 PolarHBondContact OD1-NZ 3.45Å; D319-K323 WeakPolarHBondContact OD2-CE 3.34Å; D319-K323 IonicContact OD2-NZ 3.26Å; D319-K323 PolarHBondContact OD2-NZ 2.8Å
320A85.3Confident86.5Confident40 Ų4041 Ų4133%0.33122%0.222SC..Hα-helixtrans-64.9-43.5-179.700000112.4Y318 S324Y318-A320 PolarHBondContact O-N 2.94Å; A320-S324 WeakPolarHBondContact O-CB 3.34Å; A320-S324 PolarHBondContact O-N 3.08Å; A320-S324 VanDerWaalsContact O-N 3.08Å
321Q88.5Confident86.6Confident35 Ų3536.8 Ų36.816%0.16420%0.204CC..Hα-helixtrans-72-37.6-179.1-65.3-51.9-53.600112.1N307 K310 L311 S317 Y318 L325N307-Q321 PolarHBondContact OD1-OE1 3.38Å; N307-Q321 VanDerWaalsContact OD1-OE1 3.04Å; K310-Q321 HydrophobicContact CB-CG 4.3Å; L311-Q321 HydrophobicContact CB-CB 4.4Å; L311-Q321 HydrophobicContact CD1-CB 3.69Å; S317-Q321 WeakPolarHBondContact O-CB 3.27Å; S317-Q321 VanDerWaalsContact O-CG 3.24Å; S317-Q321 WeakPolarHBondContact O-CG 3.28Å; S317-Q321 PolarHBondContact O-N 3.3Å; Y318-Q321 PolarHBondContact O-N 2.91Å; Q321-L325 VanDerWaalsContact O-CB 3.24Å; Q321-L325 WeakPolarHBondContact O-CB 3.19Å; Q321-L325 PolarHBondContact O-N 2.9Å
322M89.9Confident87Confident26 Ų2636.8 Ų36.813%0.12820%0.204CC..Hα-helixtrans-60.1-55.5175.1172.5-163.970.500111L311 Y318 D319 S324 L325 L326 A442 H489L311-M322 HydrophobicContact CD1-CB 4.35Å; Y318-M322 HydrophobicContact CD2-CB 4.36Å; Y318-M322 HydrophobicContact CE1-SD 4.11Å; Y318-M322 HydrophobicContact CE2-CB 4.09Å; Y318-M322 HydrophobicContact CE2-CG 4.32Å; Y318-M322 HydrophobicContact CE2-SD 3.93Å; Y318-M322 WeakPolarHBondContact O-CB 3.25Å; Y318-M322 PolarHBondContact O-N 3.14Å; Y318-M322 PolarHBondContact OH-SD 3.01Å; D319-M322 PolarHBondContact O-N 3.47Å; M322-S324 VanDerWaalsContact C-N 3.31Å; M322-S324 PolarHBondContact O-N 3.46Å; M322-L325 PolarHBondContact O-N 3.32Å; M322-L326 HydrophobicContact CG-CD1 4.03Å; M322-L326 WeakPolarHBondContact O-CG 3.4Å; M322-L326 PolarHBondContact O-N 2.95Å; M322-A442 HydrophobicContact CB-CB 4.37Å; M322-A442 HydrophobicContact CG-CB 3.79Å; M322-H489 VanDerWaalsContact SD-CE1 3.59Å
323K88.9Confident87.3Confident79 Ų7936.7 Ų36.734%0.34320%0.204SC..Hα-helixtrans-59.8-43.9-178.8-73.2174179.7165.80111.2E271 D319 R327E271-K323 WeakPolarHBondContact OE1-CB 3.4Å; E271-K323 WeakPolarHBondContact OE1-CD 3.07Å; E271-K323 IonicContact OE2-NZ 2.76Å; D319-K323 WeakPolarHBondContact O-CB 3.39Å; D319-K323 WeakPolarHBondContact O-CG 3.45Å; D319-K323 PolarHBondContact O-N 3.43Å; D319-K323 WeakPolarHBondContact OD1-CE 3.37Å; D319-K323 IonicContact OD1-NZ 2.84Å; D319-K323 PolarHBondContact OD1-NZ 3.45Å; D319-K323 WeakPolarHBondContact OD2-CE 3.34Å; D319-K323 IonicContact OD2-NZ 3.26Å; D319-K323 PolarHBondContact OD2-NZ 2.8Å; K323-R327 WeakPolarHBondContact O-CB 3.46Å; K323-R327 PolarHBondContact O-N 2.97Å
324S91Very high87.7Confident5 Ų537 Ų374%0.03520%0.2CC..Hα-helixtrans-60.2-50.8176-169.80000112.3Q269 N307 A320 M322 R327 I328Q269-S324 WeakPolarHBondContact CA-OG 3.36Å; Q269-S324 WeakPolarHBondContact CB-OG 3.47Å; Q269-S324 WeakPolarHBondContact CG-OG 3.18Å; N307-S324 PolarHBondContact ND2-OG 3.42Å; A320-S324 WeakPolarHBondContact O-CB 3.34Å; A320-S324 PolarHBondContact O-N 3.08Å; A320-S324 VanDerWaalsContact O-N 3.08Å; M322-S324 VanDerWaalsContact C-N 3.31Å; M322-S324 PolarHBondContact O-N 3.46Å; S324-R327 PolarHBondContact O-N 3.34Å; S324-I328 WeakPolarHBondContact O-CD1 3.41Å; S324-I328 WeakPolarHBondContact O-CG1 3.33Å; S324-I328 PolarHBondContact O-N 2.83Å
325L93.9Very high88.6Confident0 Ų033.6 Ų33.60%018%0.182CC..Hα-helixtrans-58.6-54.1179.9174.864.3000111.7A304 L311 Q321 M322 R327 I328 V329 V443 A446A304-L325 HydrophobicContact CB-CD1 4.13Å; A304-L325 VanDerWaalsContact O-CD1 3.25Å; A304-L325 WeakPolarHBondContact O-CD1 3.4Å; L311-L325 HydrophobicContact CD2-CD2 3.98Å; Q321-L325 VanDerWaalsContact O-CB 3.24Å; Q321-L325 WeakPolarHBondContact O-CB 3.19Å; Q321-L325 PolarHBondContact O-N 2.9Å; M322-L325 PolarHBondContact O-N 3.32Å; L325-R327 VanDerWaalsContact C-N 3.27Å; L325-R327 PolarHBondContact O-N 3.41Å; L325-I328 PolarHBondContact O-N 3.24Å; L325-V329 HydrophobicContact CD1-CG2 4.03Å; L325-V329 VanDerWaalsContact O-CG2 3.31Å; L325-V329 WeakPolarHBondContact O-CG2 3.32Å; L325-V329 PolarHBondContact O-N 2.97Å; L325-V443 HydrophobicContact CD2-CG2 4.19Å; L325-A446 HydrophobicContact CD1-CB 4.5Å; L325-A446 HydrophobicContact CD2-CB 4.08Å; L325-A446 HydrophobicContact CG-CB 4.14Å
326L91.7Very high89.3Confident13 Ų1328.9 Ų28.97%0.06815%0.148CC..Hα-helixtrans-62-38.1-177.3-65.9178.9000111.3M322 V329 R330 Q445 A446 M449M322-L326 HydrophobicContact CG-CD1 4.03Å; M322-L326 WeakPolarHBondContact O-CG 3.4Å; M322-L326 PolarHBondContact O-N 2.95Å; L326-V329 PolarHBondContact O-N 3.01Å; L326-R330 WeakPolarHBondContact O-CB 3.38Å; L326-R330 WeakPolarHBondContact O-CG 3.48Å; L326-R330 PolarHBondContact O-N 2.75Å; L326-Q445 HydrophobicContact CD2-CB 4.11Å; L326-Q445 HydrophobicContact CD2-CG 3.92Å; L326-A446 HydrophobicContact CD2-CB 4.33Å; L326-M449 HydrophobicContact CD2-SD 4.23Å
327R92.8Very high89.6Confident17 Ų1733.9 Ų33.96%0.06416%0.164CC..Hα-helixtrans-63-47.9174.7176.2171.9168.2150.2-2.1112.5T268 N270 E271 V273 E275 K323 S324 L325 V329 R330 I331T268-R327 WeakPolarHBondContact O-CD 3.4Å; T268-R327 PolarHBondContact O-NE 2.82Å; T268-R327 VanDerWaalsContact O-NE 3.14Å; N270-R327 PolarHBondContact O-NH1 2.88Å; N270-R327 VanDerWaalsContact O-NH1 3.14Å; N270-R327 PolarHBondContact O-NH2 3.05Å; E271-R327 PolarHBondContact O-NH1 3.03Å; V273-R327 PolarHBondContact O-NH1 3.04Å; V273-R327 PolarHBondContact O-NH2 2.81Å; E275-R327 HydrophobicContact CG-CG 4.21Å; K323-R327 WeakPolarHBondContact O-CB 3.46Å; K323-R327 PolarHBondContact O-N 2.97Å; S324-R327 PolarHBondContact O-N 3.34Å; L325-R327 VanDerWaalsContact C-N 3.27Å; L325-R327 PolarHBondContact O-N 3.41Å; R327-V329 VanDerWaalsContact C-N 3.34Å; R327-V329 PolarHBondContact O-N 3.29Å; R327-R330 PolarHBondContact O-N 3.48Å; R327-I331 HydrophobicContact CG-CD1 4.17Å; R327-I331 WeakPolarHBondContact O-CG1 3.38Å; R327-I331 PolarHBondContact O-N 3.31Å
328I93.8Very high89.5Confident0 Ų034 Ų340%016%0.159CC..Hα-helixtrans-61.2-45.4177.4-62.8155.5000110.3Q269 L300 V303 A304 N307 S324 L325 R330 I331 F332Q269-I328 HydrophobicContact CG-CD1 3.88Å; L300-I328 HydrophobicContact CB-CG2 4.34Å; L300-I328 HydrophobicContact CD2-CG2 4.22Å; L300-I328 WeakPolarHBondContact O-CG2 3.37Å; V303-I328 HydrophobicContact CG1-CD1 3.7Å; A304-I328 HydrophobicContact CB-CB 4.42Å; A304-I328 HydrophobicContact CB-CG2 3.83Å; N307-I328 WeakPolarHBondContact ND2-CD1 3.48Å; S324-I328 WeakPolarHBondContact O-CD1 3.41Å; S324-I328 WeakPolarHBondContact O-CG1 3.33Å; S324-I328 PolarHBondContact O-N 2.83Å; L325-I328 PolarHBondContact O-N 3.24Å; I328-R330 PolarHBondContact O-N 3.01Å; I328-I331 PolarHBondContact O-N 2.9Å; I328-F332 WeakPolarHBondContact O-CB 3.23Å; I328-F332 PolarHBondContact O-N 3.36Å
329V93.3Very high89Confident1 Ų131.5 Ų31.51%0.00615%0.15CC..Hα-helixtrans-65.8-37.9-178.9175.60000111.1A304 L325 L326 R327 F332 C333 A446 M449A304-V329 HydrophobicContact CB-CG2 4.05Å; L325-V329 HydrophobicContact CD1-CG2 4.03Å; L325-V329 VanDerWaalsContact O-CG2 3.31Å; L325-V329 WeakPolarHBondContact O-CG2 3.32Å; L325-V329 PolarHBondContact O-N 2.97Å; L326-V329 PolarHBondContact O-N 3.01Å; R327-V329 VanDerWaalsContact C-N 3.34Å; R327-V329 PolarHBondContact O-N 3.29Å; V329-F332 PolarHBondContact O-N 3.12Å; V329-C333 WeakPolarHBondContact O-CB 3.45Å; V329-C333 PolarHBondContact O-N 2.89Å; V329-C333 PolarHBondContact O-SG 3.41Å; V329-A446 HydrophobicContact CG1-CB 4.45Å; V329-A446 HydrophobicContact CG2-CB 4.04Å; V329-M449 HydrophobicContact CB-CE 4.32Å; V329-M449 HydrophobicContact CG1-CB 3.9Å; V329-M449 HydrophobicContact CG1-CE 3.95Å; V329-M449 HydrophobicContact CG1-SD 4.35Å
330R93.1Very high87.9Confident91 Ų9132.7 Ų32.734%0.34316%0.162SC..Hα-helixtrans-58.1-49.6171-81-167.5-62.1-96.23.6111.9E275 L326 R327 I328 C333 H334 M449E275-R330 WeakPolarHBondContact OE1-CB 3.43Å; E275-R330 IonicContact OE1-NE 2.82Å; E275-R330 PolarHBondContact OE1-NE 3.4Å; E275-R330 VanDerWaalsContact OE1-NE 3.08Å; E275-R330 IonicContact OE2-CZ 2.73Å; E275-R330 IonicContact OE2-NE 3.25Å; E275-R330 PolarHBondContact OE2-NE 3.29Å; E275-R330 VanDerWaalsContact OE2-NE 3.13Å; E275-R330 IonicContact OE2-NH2 3.5Å; E275-R330 PolarHBondContact OE2-NH2 2.93Å; L326-R330 WeakPolarHBondContact O-CB 3.38Å; L326-R330 WeakPolarHBondContact O-CG 3.48Å; L326-R330 PolarHBondContact O-N 2.75Å; R327-R330 PolarHBondContact O-N 3.48Å; I328-R330 PolarHBondContact O-N 3.01Å; R330-C333 PolarHBondContact O-N 3.27Å; R330-H334 WeakPolarHBondContact O-CB 3.26Å; R330-H334 PolarHBondContact O-N 2.9Å; R330-M449 HydrophobicContact CB-CE 4.07Å; R330-M449 HydrophobicContact CG-CE 3.23Å
331I91.4Very high86.4Confident0 Ų033.1 Ų33.10%016%0.163CC..Hα-helixtrans-62.2-46.4178.9-65.8168.5000110.4T268 E275 L278 R279 L282 L300 R327 I328 C333 H334 V335T268-I331 HydrophobicContact CG2-CD1 4.08Å; E275-I331 HydrophobicContact CG-CD1 4.14Å; E275-I331 HydrophobicContact CG-CG1 4.03Å; L278-I331 HydrophobicContact CB-CD1 4.38Å; R279-I331 HydrophobicContact CG-CG1 4.03Å; L282-I331 HydrophobicContact CD1-CG2 3.48Å; L282-I331 VanDerWaalsContact CD1-CG2 3.48Å; L300-I331 HydrophobicContact CD1-CG2 4.12Å; R327-I331 HydrophobicContact CG-CD1 4.17Å; R327-I331 WeakPolarHBondContact O-CG1 3.38Å; R327-I331 PolarHBondContact O-N 3.31Å; I328-I331 PolarHBondContact O-N 2.9Å; I331-C333 PolarHBondContact O-N 3.44Å; I331-H334 WeakPolarHBondContact O-CB 3.26Å; I331-H334 PolarHBondContact O-N 3.33Å; I331-V335 HydrophobicContact CG2-CG2 4.46Å; I331-V335 WeakPolarHBondContact O-CG2 3.24Å; I331-V335 PolarHBondContact O-N 2.83Å
332F93.5Very high84.3Confident1 Ų135.3 Ų35.30%0.00418%0.182CC..Hα-helixtrans-56.5-49.5176.3171.5-84.6000111.5L297 L300 A301 I328 V329 H334 V335 F336 V361 F362 L365L297-F332 HydrophobicContact CB-CD2 4.33Å; L297-F332 HydrophobicContact CB-CE2 3.93Å; L297-F332 HydrophobicContact CD2-CD2 3.67Å; L297-F332 HydrophobicContact CD2-CE2 3.8Å; L297-F332 HydrophobicContact CD2-CG 4.22Å; L297-F332 HydrophobicContact CD2-CZ 4.42Å; L297-F332 WeakPolarHBondContact CD2-O 3.24Å; L297-F332 HydrophobicContact CG-CE2 4.45Å; L297-F332 WeakPolarHBondContact O-CD2 3.47Å; L297-F332 WeakPolarHBondContact O-CE2 3.24Å; L300-F332 HydrophobicContact CB-CB 4.27Å; L300-F332 HydrophobicContact CB-CD2 4.03Å; L300-F332 HydrophobicContact CD1-CB 4.38Å; A301-F332 HydrophobicContact CB-CD2 4.35Å; A301-F332 HydrophobicContact CB-CE2 3.96Å; I328-F332 WeakPolarHBondContact O-CB 3.23Å; I328-F332 PolarHBondContact O-N 3.36Å; V329-F332 PolarHBondContact O-N 3.12Å; F332-H334 VanDerWaalsContact C-N 3.3Å; F332-H334 PolarHBondContact O-N 3.22Å; F332-V335 PolarHBondContact O-N 3.42Å; F332-F336 VanDerWaalsContact O-CB 3.26Å; F332-F336 WeakPolarHBondContact O-CB 3.35Å; F332-F336 PolarHBondContact O-N 2.7Å; F332-V361 HydrophobicContact CE2-CG2 4.38Å; F332-V361 HydrophobicContact CZ-CG2 4.09Å; F332-F362 AromaticContact CE1-CD1 3.98Å; F332-F362 HydrophobicContact CE1-CD1 3.98Å; F332-F362 AromaticContact CE1-CE1 3.37Å; F332-F362 HydrophobicContact CE1-CE1 3.37Å; F332-F362 HydrophobicContact CE1-CE2 4.47Å; F332-F362 AromaticContact CE1-CZ 3.65Å; F332-F362 HydrophobicContact CE1-CZ 3.65Å; F332-F362 AromaticContact CZ-CD1 3.95Å; F332-F362 HydrophobicContact CZ-CD1 3.95Å; F332-F362 HydrophobicContact CZ-CD2 4.5Å; F332-F362 AromaticContact CZ-CE1 3.73Å; F332-F362 HydrophobicContact CZ-CE1 3.73Å; F332-F362 HydrophobicContact CZ-CE2 4.29Å; F332-F362 HydrophobicContact CZ-CG 4.34Å; F332-F362 AromaticContact CZ-CZ 3.9Å; F332-F362 HydrophobicContact CZ-CZ 3.9Å; F332-L365 HydrophobicContact CE1-CD1 4.15Å; F332-L365 HydrophobicContact CZ-CD1 4.14Å
333C90.9Very high82.3Confident12 Ų1238.8 Ų38.88%0.08121%0.206CC..Hα-helixtrans-62.9-37.7179.4-690000112V329 R330 I331 R337 M449 C453V329-C333 WeakPolarHBondContact O-CB 3.45Å; V329-C333 PolarHBondContact O-N 2.89Å; V329-C333 PolarHBondContact O-SG 3.41Å; R330-C333 PolarHBondContact O-N 3.27Å; I331-C333 PolarHBondContact O-N 3.44Å; C333-R337 WeakPolarHBondContact O-CG 3.32Å; C333-R337 PolarHBondContact O-N 3.44Å; C333-M449 PolarHBondContact SG-O 3.43Å; C333-C453 HydrophobicContact CB-CB 3.68Å; C333-C453 VanDerWaalsContact SG-SG 3.64Å
334H89.6Confident80Confident57 Ų5742.2 Ų42.226%0.26423%0.228SC..Hα-helixtrans-64-54.1176.2176.471.2000111.5R330 I331 F332 F336 R337R330-H334 WeakPolarHBondContact O-CB 3.26Å; R330-H334 PolarHBondContact O-N 2.9Å; I331-H334 WeakPolarHBondContact O-CB 3.26Å; I331-H334 PolarHBondContact O-N 3.33Å; F332-H334 VanDerWaalsContact C-N 3.3Å; F332-H334 PolarHBondContact O-N 3.22Å; H334-F336 VanDerWaalsContact C-N 3.28Å; H334-F336 PolarHBondContact O-N 3.05Å; H334-R337 PolarHBondContact O-N 3.28Å
335V89.1Confident77.4Confident0 Ų048.4 Ų48.40%026%0.261CS..Hα-helixtrans-60-40.7178.2176.50000110.7L282 Y293 V296 L297 I331 F332 R337 L338L282-V335 HydrophobicContact CB-CG2 4.16Å; Y293-V335 HydrophobicContact CD2-CG1 4.4Å; Y293-V335 HydrophobicContact CE2-CG1 4.28Å; Y293-V335 WeakPolarHBondContact CE2-O 3.45Å; V296-V335 HydrophobicContact CG1-CG1 4.32Å; L297-V335 HydrophobicContact CD2-CB 3.97Å; L297-V335 HydrophobicContact CD2-CG1 3.88Å; L297-V335 HydrophobicContact CG-CG1 4.17Å; I331-V335 HydrophobicContact CG2-CG2 4.46Å; I331-V335 WeakPolarHBondContact O-CG2 3.24Å; I331-V335 PolarHBondContact O-N 2.83Å; F332-V335 PolarHBondContact O-N 3.42Å; V335-R337 VanDerWaalsContact C-N 3.3Å; V335-R337 PolarHBondContact O-N 3.35Å; V335-L338 PolarHBondContact O-N 3.16Å; V335-L338 VanDerWaalsContact O-N 3.11Å
336F88.6Confident74.9Confident12 Ų1251.4 Ų51.45%0.05329%0.292CS..Hα-helixtrans-59-38.7178.5-179.7-101.3000112.9Y293 L297 F332 H334 L338 G339 R358 V361 F362 Q454Y293-F336 WeakPolarHBondContact OH-CA 3.44Å; Y293-F336 PolarHBondContact OH-O 3.15Å; L297-F336 HydrophobicContact CD1-CB 4.4Å; L297-F336 HydrophobicContact CD1-CD2 4.01Å; L297-F336 HydrophobicContact CD2-CB 4.04Å; F332-F336 VanDerWaalsContact O-CB 3.26Å; F332-F336 WeakPolarHBondContact O-CB 3.35Å; F332-F336 PolarHBondContact O-N 2.7Å; H334-F336 VanDerWaalsContact C-N 3.28Å; H334-F336 PolarHBondContact O-N 3.05Å; F336-L338 VanDerWaalsContact C-N 3.27Å; F336-L338 PolarHBondContact O-N 3.1Å; F336-G339 PolarHBondContact O-N 3.3Å; F336-R358 HydrophobicContact CE2-CG 3.66Å; F336-R358 HydrophobicContact CZ-CG 3.96Å; F336-R358 PolarHBondContact O-NH2 3.23Å; F336-V361 HydrophobicContact CD2-CG2 4.23Å; F336-V361 HydrophobicContact CE2-CG2 4.25Å; F336-F362 HydrophobicContact CD1-CZ 4.23Å; F336-F362 AromaticContact CD2-CE2 3.91Å; F336-F362 HydrophobicContact CD2-CE2 3.91Å; F336-F362 HydrophobicContact CD2-CZ 4.15Å; F336-F362 HydrophobicContact CE1-CE2 4.16Å; F336-F362 HydrophobicContact CE1-CZ 4.11Å; F336-F362 HydrophobicContact CE2-CD2 4.49Å; F336-F362 AromaticContact CE2-CE2 3.45Å; F336-F362 HydrophobicContact CE2-CE2 3.45Å; F336-F362 VanDerWaalsContact CE2-CE2 3.45Å; F336-F362 HydrophobicContact CE2-CZ 4.04Å; F336-F362 HydrophobicContact CG-CE2 4.45Å; F336-F362 HydrophobicContact CG-CZ 4.26Å; F336-F362 AromaticContact CZ-CE2 3.59Å; F336-F362 HydrophobicContact CZ-CE2 3.59Å; F336-F362 HydrophobicContact CZ-CZ 4.01Å; F336-Q454 HydrophobicContact CE1-CG 4.15Å; F336-Q454 HydrophobicContact CZ-CG 4.46Å
337R85.8Confident72.4Confident125 Ų12558.2 Ų58.247%0.47233%0.329SS..Hα-helixtrans-68.6-24.6178.9-74.8176.5178.7173.91.6113.3C333 H334 V335C333-R337 WeakPolarHBondContact O-CG 3.32Å; C333-R337 PolarHBondContact O-N 3.44Å; H334-R337 PolarHBondContact O-N 3.28Å; V335-R337 VanDerWaalsContact C-N 3.3Å; V335-R337 PolarHBondContact O-N 3.35Å
338L81.6Confident69.9Low68 Ų6862.3 Ų62.336%0.35635%0.352SS..Hα-helixtrans-79.9-15.9-178.8-64171.4000114E283 V335 F336E283-L338 HydrophobicContact CB-CD1 3.94Å; E283-L338 HydrophobicContact CG-CD1 3.63Å; V335-L338 PolarHBondContact O-N 3.16Å; V335-L338 VanDerWaalsContact O-N 3.11Å; F336-L338 VanDerWaalsContact C-N 3.27Å; F336-L338 PolarHBondContact O-N 3.1Å
339G72Confident67.6Low4 Ų466.8 Ų66.84%0.04137%0.374CS..SBendtrans-61161.7-174.600000114.7Y293 F336 S341Y293-G339 VanDerWaalsContact CE2-CA 3.43Å; F336-G339 PolarHBondContact O-N 3.3Å; G339-S341 CarbonylContact O-C 3.49Å; G339-S341 PolarHBondContact O-N 2.84Å
340P61Low64.9Low101 Ų10169.1 Ų69.166%0.65640%0.398SS*.SBendtrans-62.37-167.124.3-35.5000117
341S54.4Low62.6Low49 Ų4971.5 Ų71.534%0.34341%0.408SS..  trans-130.777.5171.928.10000108.5G339 R358G339-S341 CarbonylContact O-C 3.49Å; G339-S341 PolarHBondContact O-N 2.84Å; S341-R358 VanDerWaalsContact O-CZ 3.31Å; S341-R358 PolarHBondContact O-NH1 2.9Å; S341-R358 VanDerWaalsContact O-NH1 3.14Å; S341-R358 WeakPolarHBondContact OG-CD 3.36Å; S341-R358 PolarHBondContact OG-NH1 3.38Å
342S44.8Very low59.9Low80 Ų8078.2 Ų78.256%0.55944%0.444SS*.  trans-58.9148.1160.7-94.60000109.4N344S342-N344 PolarHBondContact O-N 3.37Å
343P47.3Very low57.4Low99 Ų9981.6 Ų81.664%0.64348%0.479SS*.SBendtrans-75.654.7-170.433.1-36.4000112.6
344N39.8Very low54.9Low151 Ų15187.5 Ų87.581%0.80751%0.51SS*.  trans-93.6-8.2176.5-100.512.5000113.8S342S342-N344 PolarHBondContact O-N 3.37Å
345N36.6Very low53.3Low135 Ų13593.1 Ų93.172%0.72253%0.534SS*.SBendtrans-127.1110.7174.1-80-19.6000109.4N347N345-N347 PolarHBondContact O-N 3.45Å
346G42.5Very low52Low63 Ų6395.2 Ų95.265%0.64955%0.547SS*.THydrogen-bonded Turntrans-62.924.2176.700000115.9
347N38.8Very low50.7Low157 Ų15798.1 Ų98.184%0.8457%0.567SS**THydrogen-bonded Turntrans-100-7.3179.9-76.9-0.1000114N345 M349N345-N347 PolarHBondContact O-N 3.45Å; N347-M349 VanDerWaalsContact C-N 3.29Å
348D40.2Very low50.1Low103 Ų10394.1 Ų94.155%0.55155%0.552SS**SBendtrans-87.41.8169.4-104.3-10.1000112.6G350D348-G350 PolarHBondContact O-N 3.21Å
349M45.6Very low49.8Very low93 Ų9393.5 Ų93.546%0.45855%0.553SS.*  trans-77.143.2177.6-71.7-72.2-158.800112.9N347 Y351 M455 P456N347-M349 VanDerWaalsContact C-N 3.29Å; M349-Y351 PolarHBondContact O-N 2.89Å; M349-M455 HydrophobicContact CE-CE 4.3Å; M349-M455 HydrophobicContact CE-SD 4.43Å; M349-P456 HydrophobicContact CE-CG 4.28Å
350G35.8Very low50.2Low50 Ų5098.3 Ų98.352%0.51558%0.575SS.*  trans-82.193.4175.500000111.6D348 N352D348-G350 PolarHBondContact O-N 3.21Å; G350-N352 PolarHBondContact O-N 3.12Å
351Y46.1Very low51.3Low142 Ų14293.6 Ų93.656%0.55754%0.544SS*.SBendtrans-60.86.5167.2-93.6-93.7000114.5M349 P462M349-Y351 PolarHBondContact O-N 2.89Å; Y351-P462 WeakPolarHBondContact OH-CB 3.42Å; Y351-P462 WeakPolarHBondContact OH-CD 3.39Å; Y351-P462 VanDerWaalsContact OH-CG 3.27Å; Y351-P462 WeakPolarHBondContact OH-CG 3.47Å
352N34.6Very low52.9Low140 Ų14091.6 Ų91.675%0.74953%0.529SS*.SBendtrans-129.5102.4173.8-88-21.1000109.8G350 N354G350-N352 PolarHBondContact O-N 3.12Å; N352-N354 PolarHBondContact O-N 3.39Å
353G41Very low54.9Low73 Ų7395.4 Ų95.475%0.75354%0.536SS*.  trans56.24.913800000120.6K355G353-K355 PolarHBondContact O-N 2.94Å
354N38.6Very low57Low135 Ų13591.6 Ų91.672%0.72251%0.511SS*.  trans-78.597.6173.1-79.4-11000107.8N352 T356N352-N354 PolarHBondContact O-N 3.39Å; N354-T356 PolarHBondContact O-N 3.27Å
355K54.8Low59.4Low175 Ų17584.5 Ų84.576%0.76147%0.473SS*.  trans-64.869.1178.6-63.7176.8-178.8174.70110.9G353G353-K355 PolarHBondContact O-N 2.94Å
356T62.4Low61.9Low45 Ų4580.2 Ų80.228%0.27645%0.448SS..  trans-64.3144.1168.6620000108.4N354 R358 S359 Q360N354-T356 PolarHBondContact O-N 3.27Å; T356-R358 PolarHBondContact O-N 3.37Å; T356-S359 PolarHBondContact N-OG 3.06Å; T356-S359 PolarHBondContact O-N 2.99Å; T356-S359 PolarHBondContact O-OG 3.24Å; T356-S359 PolarHBondContact OG1-N 3.27Å; T356-S359 PolarHBondContact OG1-OG 3.01Å; T356-Q360 PolarHBondContact O-N 3.11Å
357P62Low64.1Low73 Ų7382.5 Ų82.547%0.47445%0.445SS..Hα-helixtrans-54.9-25.7175.3-25.734.1000112.9
358R72.4Confident66.6Low40 Ų4075 Ų7515%0.15141%0.405CS..Hα-helixtrans-68.5-34.1175.4-172.9175179.29715.9113.8F336 S341 T356 V361F336-R358 HydrophobicContact CE2-CG 3.66Å; F336-R358 HydrophobicContact CZ-CG 3.96Å; F336-R358 PolarHBondContact O-NH2 3.23Å; S341-R358 VanDerWaalsContact O-CZ 3.31Å; S341-R358 PolarHBondContact O-NH1 2.9Å; S341-R358 VanDerWaalsContact O-NH1 3.14Å; S341-R358 WeakPolarHBondContact OG-CD 3.36Å; S341-R358 PolarHBondContact OG-NH1 3.38Å; T356-R358 PolarHBondContact O-N 3.37Å; R358-V361 VanDerWaalsContact O-CG2 3.3Å; R358-V361 WeakPolarHBondContact O-CG2 3.36Å
359S74.3Confident69.1Low55 Ų5570.7 Ų70.739%0.38538%0.381SS..Hα-helixtrans-83.5-21.4177.661.10000113.1T356 V361 F362T356-S359 PolarHBondContact N-OG 3.06Å; T356-S359 PolarHBondContact O-N 2.99Å; T356-S359 PolarHBondContact O-OG 3.24Å; T356-S359 PolarHBondContact OG1-N 3.27Å; T356-S359 PolarHBondContact OG1-OG 3.01Å; S359-V361 PolarHBondContact O-N 3.48Å; S359-F362 PolarHBondContact O-N 3.06Å
360Q81.3Confident71.3Confident106 Ų10671.7 Ų71.750%0.49538%0.384SS..Hα-helixtrans-63.7-26.3-179.2-68.4-176.613.900113.9T356 F362 K363T356-Q360 PolarHBondContact O-N 3.11Å; Q360-F362 PolarHBondContact O-N 3.16Å; Q360-K363 VanDerWaalsContact O-CB 3.23Å; Q360-K363 WeakPolarHBondContact O-CB 3.23Å; Q360-K363 PolarHBondContact O-N 3.02Å; Q360-K363 VanDerWaalsContact O-N 3.09Å
361V84.6Confident73.8Confident2 Ų270.7 Ų70.71%0.01237%0.37CS..THydrogen-bonded Turntrans-65.1-19.4179.4-55.60000113.4L297 A301 F332 F336 R358 S359 P364L297-V361 HydrophobicContact CB-CB 3.86Å; L297-V361 HydrophobicContact CB-CG1 3.9Å; L297-V361 HydrophobicContact CB-CG2 4.26Å; L297-V361 HydrophobicContact CD1-CG1 4.31Å; L297-V361 HydrophobicContact CD1-CG2 4.26Å; A301-V361 WeakPolarHBondContact CB-O 3.44Å; F332-V361 HydrophobicContact CE2-CG2 4.38Å; F332-V361 HydrophobicContact CZ-CG2 4.09Å; F336-V361 HydrophobicContact CD2-CG2 4.23Å; F336-V361 HydrophobicContact CE2-CG2 4.25Å; R358-V361 VanDerWaalsContact O-CG2 3.3Å; R358-V361 WeakPolarHBondContact O-CG2 3.36Å; S359-V361 PolarHBondContact O-N 3.48Å; V361-P364 WeakPolarHBondContact O-CD 3.46Å
362F87.3Confident76Confident7 Ų764 Ų643%0.03134%0.343CS..THydrogen-bonded Turntrans-84.6-12175.9-70.5-89.9000113.4F332 F336 S359 Q360 P364 L365 E366 Q454F332-F362 AromaticContact CE1-CD1 3.98Å; F332-F362 HydrophobicContact CE1-CD1 3.98Å; F332-F362 AromaticContact CE1-CE1 3.37Å; F332-F362 HydrophobicContact CE1-CE1 3.37Å; F332-F362 HydrophobicContact CE1-CE2 4.47Å; F332-F362 AromaticContact CE1-CZ 3.65Å; F332-F362 HydrophobicContact CE1-CZ 3.65Å; F332-F362 AromaticContact CZ-CD1 3.95Å; F332-F362 HydrophobicContact CZ-CD1 3.95Å; F332-F362 HydrophobicContact CZ-CD2 4.5Å; F332-F362 AromaticContact CZ-CE1 3.73Å; F332-F362 HydrophobicContact CZ-CE1 3.73Å; F332-F362 HydrophobicContact CZ-CE2 4.29Å; F332-F362 HydrophobicContact CZ-CG 4.34Å; F332-F362 AromaticContact CZ-CZ 3.9Å; F332-F362 HydrophobicContact CZ-CZ 3.9Å; F336-F362 HydrophobicContact CD1-CZ 4.23Å; F336-F362 AromaticContact CD2-CE2 3.91Å; F336-F362 HydrophobicContact CD2-CE2 3.91Å; F336-F362 HydrophobicContact CD2-CZ 4.15Å; F336-F362 HydrophobicContact CE1-CE2 4.16Å; F336-F362 HydrophobicContact CE1-CZ 4.11Å; F336-F362 HydrophobicContact CE2-CD2 4.49Å; F336-F362 AromaticContact CE2-CE2 3.45Å; F336-F362 HydrophobicContact CE2-CE2 3.45Å; F336-F362 VanDerWaalsContact CE2-CE2 3.45Å; F336-F362 HydrophobicContact CE2-CZ 4.04Å; F336-F362 HydrophobicContact CG-CE2 4.45Å; F336-F362 HydrophobicContact CG-CZ 4.26Å; F336-F362 AromaticContact CZ-CE2 3.59Å; F336-F362 HydrophobicContact CZ-CE2 3.59Å; F336-F362 HydrophobicContact CZ-CZ 4.01Å; S359-F362 PolarHBondContact O-N 3.06Å; Q360-F362 PolarHBondContact O-N 3.16Å; F362-P364 VanDerWaalsContact C-CD 3.44Å; F362-P364 VanDerWaalsContact C-N 3.32Å; F362-L365 HydrophobicContact CD1-CD1 4.03Å; F362-L365 WeakPolarHBondContact O-CA 3.31Å; F362-L365 WeakPolarHBondContact O-CB 3.35Å; F362-L365 PolarHBondContact O-N 2.81Å; F362-E366 PolarHBondContact O-N 3.35Å; F362-Q454 HydrophobicContact CE1-CG 4.26Å; F362-Q454 HydrophobicContact CE2-CG 4.04Å; F362-Q454 HydrophobicContact CZ-CG 3.64Å; F362-Q454 VanDerWaalsContact CZ-NE2 3.34Å
363K87.4Confident78.6Confident160 Ų16059.1 Ų59.170%0.69632%0.317SS*.Hα-helixtrans-53.8-39.3-176.1-173.5-178.1177.8-171.50113.9Q360 L365 E366Q360-K363 VanDerWaalsContact O-CB 3.23Å; Q360-K363 WeakPolarHBondContact O-CB 3.23Å; Q360-K363 PolarHBondContact O-N 3.02Å; Q360-K363 VanDerWaalsContact O-N 3.09Å; K363-L365 VanDerWaalsContact C-N 3.32Å; K363-L365 PolarHBondContact O-N 3.13Å; K363-E366 PolarHBondContact O-N 3.13Å
364P90.6Very high80.9Confident19 Ų1961.8 Ų61.812%0.12331%0.31CS..Hα-helixtrans-62.2-38.4173.6-22.734.7000112.8T298 A301 E302 T305 V361 F362 L367T298-P364 HydrophobicContact CG2-CG 4.32Å; A301-P364 HydrophobicContact CB-CB 3.98Å; A301-P364 HydrophobicContact CB-CG 3.97Å; E302-P364 HydrophobicContact CG-CB 4.03Å; E302-P364 HydrophobicContact CG-CG 3.96Å; T305-P364 WeakPolarHBondContact CG2-O 3.44Å; T305-P364 PolarHBondContact OG1-O 3.02Å; V361-P364 WeakPolarHBondContact O-CD 3.46Å; F362-P364 VanDerWaalsContact C-CD 3.44Å; F362-P364 VanDerWaalsContact C-N 3.32Å; P364-L367 PolarHBondContact O-N 3.09Å
365L90.3Very high83.2Confident1 Ų157.9 Ų57.91%0.00529%0.285CS..Hα-helixtrans-70.1-31.6179.4-69.5169.4000112.1A301 A304 T305 F332 F362 K363 L367 L368 W369A301-L365 HydrophobicContact CB-CD1 4.22Å; A301-L365 HydrophobicContact CB-CG 3.97Å; A304-L365 HydrophobicContact CB-CD2 3.8Å; T305-L365 WeakPolarHBondContact OG1-CA 3.29Å; T305-L365 PolarHBondContact OG1-N 3.09Å; F332-L365 HydrophobicContact CE1-CD1 4.15Å; F332-L365 HydrophobicContact CZ-CD1 4.14Å; F362-L365 HydrophobicContact CD1-CD1 4.03Å; F362-L365 WeakPolarHBondContact O-CA 3.31Å; F362-L365 WeakPolarHBondContact O-CB 3.35Å; F362-L365 PolarHBondContact O-N 2.81Å; K363-L365 VanDerWaalsContact C-N 3.32Å; K363-L365 PolarHBondContact O-N 3.13Å; L365-L367 PolarHBondContact O-N 2.8Å; L365-L368 WeakPolarHBondContact O-CA 3.33Å; L365-L368 WeakPolarHBondContact O-CB 3.45Å; L365-L368 PolarHBondContact O-N 3.06Å; L365-W369 HydrophobicContact CB-CZ2 3.75Å; L365-W369 HydrophobicContact CD1-CZ2 4.28Å; L365-W369 HydrophobicContact CD2-CH2 4.27Å; L365-W369 HydrophobicContact CD2-CZ2 3.91Å; L365-W369 HydrophobicContact CG-CZ2 4.19Å; L365-W369 VanDerWaalsContact O-CD1 3.24Å; L365-W369 VanDerWaalsContact O-CG 3.24Å; L365-W369 PolarHBondContact O-N 3.09Å; L365-W369 PolarHBondContact O-NE1 3.44Å
366E89.7Confident84.8Confident46 Ų4649.5 Ų49.522%0.21525%0.249CC..Hα-helixtrans-55.8-35.3175.6-66.8-61.5161.300112.9F362 K363 L368 W369 H370 R463F362-E366 PolarHBondContact O-N 3.35Å; K363-E366 PolarHBondContact O-N 3.13Å; E366-L368 VanDerWaalsContact C-N 3.31Å; E366-L368 PolarHBondContact O-N 3.14Å; E366-W369 PolarHBondContact O-N 3.45Å; E366-H370 PolarHBondContact O-CD2 2.74Å; E366-H370 PolarHBondContact O-N 3.24Å; E366-R463 IonicContact OE1-CZ 3.97Å; E366-R463 IonicContact OE1-NH1 3.1Å; E366-R463 PolarHBondContact OE1-NH1 3.44Å; E366-R463 IonicContact OE1-NH2 3.16Å; E366-R463 PolarHBondContact OE1-NH2 3.34Å; E366-R463 IonicContact OE2-CZ 3.04Å; E366-R463 IonicContact OE2-NH1 3.87Å; E366-R463 IonicContact OE2-NH2 3.93Å; E366-R463 PolarHBondContact OE2-NH2 3.5Å
367L89.1Confident85.9Confident111 Ų11151 Ų5158%0.58125%0.254SS*.Hα-helixtrans-63.6-38.2175.2-63173.9000112P364 L365 S371P364-L367 PolarHBondContact O-N 3.09Å; L365-L367 PolarHBondContact O-N 2.8Å; L367-S371 PolarHBondContact O-N 2.92Å; L367-S371 PolarHBondContact O-OG 3.34Å
368L91Very high87Confident0 Ų051.9 Ų51.90%025%0.254CS..Hα-helixtrans-67.9-41.8176.2179.562.2000111.1T305 G308 L312 L365 E366 H370 S371 L372 V443T305-L368 HydrophobicContact CG2-CB 4.28Å; G308-L368 VanDerWaalsContact C-CD1 3.49Å; L312-L368 HydrophobicContact CD1-CD1 3.86Å; L365-L368 WeakPolarHBondContact O-CA 3.33Å; L365-L368 WeakPolarHBondContact O-CB 3.45Å; L365-L368 PolarHBondContact O-N 3.06Å; E366-L368 VanDerWaalsContact C-N 3.31Å; E366-L368 PolarHBondContact O-N 3.14Å; L368-H370 PolarHBondContact O-N 3.05Å; L368-S371 PolarHBondContact O-N 2.84Å; L368-L372 PolarHBondContact O-N 3.1Å; L368-V443 HydrophobicContact CD1-CG1 4.1Å; L368-V443 HydrophobicContact CD2-CG1 4.07Å; L368-V443 HydrophobicContact CG-CG1 3.97Å
369W93.1Very high87.5Confident12 Ų1250.7 Ų50.75%0.04525%0.25CS..Hα-helixtrans-65.7-37.7179.7-47.7146.3000112.4L365 E366 L372 D373 V443 A446 F447 S450L365-W369 HydrophobicContact CB-CZ2 3.75Å; L365-W369 HydrophobicContact CD1-CZ2 4.28Å; L365-W369 HydrophobicContact CD2-CH2 4.27Å; L365-W369 HydrophobicContact CD2-CZ2 3.91Å; L365-W369 HydrophobicContact CG-CZ2 4.19Å; L365-W369 VanDerWaalsContact O-CD1 3.24Å; L365-W369 VanDerWaalsContact O-CG 3.24Å; L365-W369 PolarHBondContact O-N 3.09Å; L365-W369 PolarHBondContact O-NE1 3.44Å; E366-W369 PolarHBondContact O-N 3.45Å; W369-L372 PolarHBondContact O-N 2.82Å; W369-D373 PolarHBondContact O-N 3.18Å; W369-V443 HydrophobicContact CE3-CG1 4.42Å; W369-V443 HydrophobicContact CZ3-CG1 4Å; W369-A446 HydrophobicContact CH2-CB 4.06Å; W369-A446 HydrophobicContact CZ3-CB 4.4Å; W369-F447 HydrophobicContact CB-CD2 4.29Å; W369-F447 HydrophobicContact CB-CE2 4.22Å; W369-F447 AromaticContact CD1-CD2 3.76Å; W369-F447 AromaticContact CD1-CE2 3.71Å; W369-F447 HydrophobicContact CD2-CB 4.17Å; W369-F447 AromaticContact CD2-CD2 3.39Å; W369-F447 HydrophobicContact CD2-CD2 3.39Å; W369-F447 HydrophobicContact CD2-CE2 4.09Å; W369-F447 HydrophobicContact CD2-CG 4.06Å; W369-F447 AromaticContact CE2-CD2 3.56Å; W369-F447 HydrophobicContact CE3-CB 3.7Å; W369-F447 AromaticContact CE3-CD2 3.84Å; W369-F447 HydrophobicContact CE3-CD2 3.84Å; W369-F447 HydrophobicContact CE3-CG 4.02Å; W369-F447 AromaticContact CG-CD2 3.57Å; W369-F447 HydrophobicContact CG-CD2 3.57Å; W369-F447 AromaticContact CG-CE2 3.75Å; W369-F447 HydrophobicContact CG-CE2 3.75Å; W369-F447 HydrophobicContact CG-CG 4.45Å; W369-F447 HydrophobicContact CH2-CB 4.06Å; W369-F447 HydrophobicContact CZ2-CB 4.47Å; W369-F447 HydrophobicContact CZ2-CD2 4.16Å; W369-F447 HydrophobicContact CZ3-CB 3.64Å; W369-F447 HydrophobicContact CZ3-CD2 4.4Å; W369-F447 HydrophobicContact CZ3-CG 4.42Å; W369-F447 AromaticContact NE1-CD2 3.75Å; W369-S450 WeakPolarHBondContact CZ2-OG 3.43Å
370H90.4Very high87.9Confident114 Ų11449.1 Ų49.153%0.52824%0.24SC..Hα-helixtrans-63-45.5172.2-75.4-54.4000112.2E366 L368 L372 D373 E374E366-H370 PolarHBondContact O-CD2 2.74Å; E366-H370 PolarHBondContact O-N 3.24Å; L368-H370 PolarHBondContact O-N 3.05Å; H370-L372 VanDerWaalsContact C-N 3.31Å; H370-L372 PolarHBondContact O-N 3.14Å; H370-D373 PolarHBondContact O-N 3.04Å; H370-E374 WeakPolarHBondContact O-CG 3.14Å; H370-E374 PolarHBondContact O-N 3.39Å
371S89.7Confident87.9Confident29 Ų2947.4 Ų47.420%0.20324%0.236CC..Hα-helixtrans-61.5-39.7175.3-58.40000112.1H309 L367 L368 E374 W375H309-S371 PolarHBondContact NE2-OG 2.97Å; L367-S371 PolarHBondContact O-N 2.92Å; L367-S371 PolarHBondContact O-OG 3.34Å; L368-S371 PolarHBondContact O-N 2.84Å; S371-E374 PolarHBondContact O-N 3.31Å; S371-W375 PolarHBondContact O-N 3.5Å; S371-W375 VanDerWaalsContact O-N 3.07Å
372L90.9Very high87.3Confident0 Ų049 Ų490%024%0.244CC..Hα-helixtrans-60.9-45.7175175.265.5000111.7L368 W369 H370 E374 W375 L376 L440 V443 I444 F467L368-L372 PolarHBondContact O-N 3.1Å; W369-L372 PolarHBondContact O-N 2.82Å; H370-L372 VanDerWaalsContact C-N 3.31Å; H370-L372 PolarHBondContact O-N 3.14Å; L372-E374 VanDerWaalsContact C-N 3.35Å; L372-E374 PolarHBondContact O-N 3.11Å; L372-W375 PolarHBondContact O-N 2.91Å; L372-L376 HydrophobicContact CD1-CD1 4.21Å; L372-L376 HydrophobicContact CD1-CG 4.25Å; L372-L376 HydrophobicContact CG-CD1 4.2Å; L372-L376 WeakPolarHBondContact O-CG 3.15Å; L372-L376 PolarHBondContact O-N 3.43Å; L372-L440 HydrophobicContact CD1-CD2 3.83Å; L372-V443 HydrophobicContact CB-CG1 4.37Å; L372-V443 HydrophobicContact CD1-CB 4.31Å; L372-V443 HydrophobicContact CD1-CG1 4.31Å; L372-V443 HydrophobicContact CD2-CG1 4.09Å; L372-V443 HydrophobicContact CG-CG1 4.49Å; L372-I444 HydrophobicContact CD1-CG1 4.03Å; L372-I444 HydrophobicContact CD2-CG1 3.83Å; L372-I444 HydrophobicContact CG-CG1 4.43Å; L372-F467 HydrophobicContact CD2-CE2 4.32Å; L372-F467 HydrophobicContact CD2-CZ 3.74Å; L372-F467 HydrophobicContact CG-CZ 4.15Å
373D89.9Confident86.8Confident39 Ų3950.5 Ų50.521%0.20925%0.252CS..Hα-helixtrans-60.1-44.1178.4-170.772.3000111.6W369 H370 W375 L376 M377 K470 H471W369-D373 PolarHBondContact O-N 3.18Å; H370-D373 PolarHBondContact O-N 3.04Å; D373-W375 PolarHBondContact O-N 3.28Å; D373-L376 PolarHBondContact O-N 3.23Å; D373-M377 WeakPolarHBondContact O-CG 3.41Å; D373-M377 PolarHBondContact O-N 3.17Å; D373-K470 IonicContact OD1-NZ 2.77Å; D373-K470 PolarHBondContact OD1-NZ 3.16Å; D373-K470 IonicContact OD2-NZ 2.73Å; D373-K470 PolarHBondContact OD2-NZ 2.89Å; D373-H471 IonicContact OD1-CD2 3.43Å; D373-H471 IonicContact OD1-CE1 2.82Å; D373-H471 PolarHBondContact OD1-CE1 3.46Å; D373-H471 IonicContact OD1-NE2 3.96Å; D373-H471 PolarHBondContact OD1-NE2 3.23Å
374E88.7Confident86.1Confident128 Ų12847.5 Ų47.560%0.59824%0.24SC*.Hα-helixtrans-59.4-45.1175.1-71.8179.1169.300111.9H370 S371 L372 L376 M377 L378H370-E374 WeakPolarHBondContact O-CG 3.14Å; H370-E374 PolarHBondContact O-N 3.39Å; S371-E374 PolarHBondContact O-N 3.31Å; L372-E374 VanDerWaalsContact C-N 3.35Å; L372-E374 PolarHBondContact O-N 3.11Å; E374-L376 PolarHBondContact O-N 3.44Å; E374-M377 PolarHBondContact O-N 2.74Å; E374-L378 VanDerWaalsContact O-CG 3.31Å; E374-L378 WeakPolarHBondContact O-CG 3.49Å; E374-L378 PolarHBondContact O-N 2.89Å
375W87.4Confident85.1Confident53 Ų5354.5 Ų54.520%0.20126%0.264CS..Hα-helixtrans-60-46.2176.9-88109.1000112.7S371 L372 D373 L378 I379 L403 L440S371-W375 PolarHBondContact O-N 3.5Å; S371-W375 VanDerWaalsContact O-N 3.07Å; L372-W375 PolarHBondContact O-N 2.91Å; D373-W375 PolarHBondContact O-N 3.28Å; W375-L378 PolarHBondContact O-N 2.87Å; W375-I379 WeakPolarHBondContact O-CG1 3.33Å; W375-I379 PolarHBondContact O-N 3.42Å; W375-I379 VanDerWaalsContact O-N 3.13Å; W375-L403 HydrophobicContact CH2-CD2 3.1Å; W375-L403 HydrophobicContact CH2-CG 3.73Å; W375-L403 HydrophobicContact CZ2-CD2 3.96Å; W375-L403 HydrophobicContact CZ3-CD2 3.44Å; W375-L403 VanDerWaalsContact CZ3-CD2 3.44Å; W375-L403 HydrophobicContact CZ3-CG 3.91Å; W375-L440 HydrophobicContact CB-CD2 3.92Å; W375-L440 HydrophobicContact CG-CD2 4.27Å
376L87.9Confident83.7Confident0 Ų057.6 Ų57.60%029%0.286CS..Hα-helixtrans-68.6-38-179.7-65.2176.1000111.9L372 D373 E374 L378 I379 S380 L440 I444 F467 H471 V474 F478L372-L376 HydrophobicContact CD1-CD1 4.21Å; L372-L376 HydrophobicContact CD1-CG 4.25Å; L372-L376 HydrophobicContact CG-CD1 4.2Å; L372-L376 WeakPolarHBondContact O-CG 3.15Å; L372-L376 PolarHBondContact O-N 3.43Å; D373-L376 PolarHBondContact O-N 3.23Å; E374-L376 PolarHBondContact O-N 3.44Å; L376-L378 VanDerWaalsContact C-N 3.35Å; L376-L378 PolarHBondContact O-N 3.38Å; L376-I379 PolarHBondContact O-N 3.34Å; L376-S380 WeakPolarHBondContact O-CB 3.5Å; L376-S380 PolarHBondContact O-N 3.44Å; L376-L440 HydrophobicContact CD2-CD1 4.45Å; L376-I444 HydrophobicContact CD1-CD1 4.29Å; L376-I444 HydrophobicContact CD2-CD1 4.4Å; L376-F467 HydrophobicContact CD1-CE1 4.23Å; L376-F467 HydrophobicContact CD1-CE2 3.96Å; L376-F467 HydrophobicContact CD1-CZ 3.38Å; L376-H471 WeakPolarHBondContact CB-ND1 3.49Å; L376-H471 HydrophobicContact CD1-CB 4.2Å; L376-V474 HydrophobicContact CD2-CG1 3.83Å; L376-F478 HydrophobicContact CD2-CE2 4.07Å; L376-F478 HydrophobicContact CD2-CZ 4.11Å
377M86.8Confident82.2Confident76 Ų7660.7 Ų60.737%0.37431%0.308SS..Hα-helixtrans-60.8-43.1173.3-74-53.5-56.400111.8D373 E374 I379 S380 T381D373-M377 WeakPolarHBondContact O-CG 3.41Å; D373-M377 PolarHBondContact O-N 3.17Å; E374-M377 PolarHBondContact O-N 2.74Å; M377-I379 PolarHBondContact O-N 3.19Å; M377-S380 WeakPolarHBondContact O-CB 3.32Å; M377-S380 PolarHBondContact O-N 3.36Å; M377-T381 WeakPolarHBondContact O-CG2 3.46Å; M377-T381 PolarHBondContact O-N 2.99Å; M377-T381 PolarHBondContact O-OG1 2.97Å
378L83.8Confident80.7Confident92 Ų9262.4 Ų62.448%0.48231%0.311SS..Hα-helixtrans-60.4-45.7176.9-72171.2000111.4E374 W375 L376 S380 T381 E382E374-L378 VanDerWaalsContact O-CG 3.31Å; E374-L378 WeakPolarHBondContact O-CG 3.49Å; E374-L378 PolarHBondContact O-N 2.89Å; W375-L378 PolarHBondContact O-N 2.87Å; L376-L378 VanDerWaalsContact C-N 3.35Å; L376-L378 PolarHBondContact O-N 3.38Å; L378-S380 VanDerWaalsContact C-N 3.35Å; L378-S380 PolarHBondContact O-N 2.93Å; L378-T381 PolarHBondContact O-N 3.49Å; L378-T381 PolarHBondContact O-OG1 2.94Å; L378-E382 PolarHBondContact O-N 2.86Å; L378-E382 VanDerWaalsContact O-N 3.15Å
379I82.7Confident78.7Confident14 Ų1467.5 Ų67.57%0.07234%0.338CS..Hα-helixtrans-62.5-43.3176.8-65169.1000110.8W375 L376 M377 T381 E382 L383 I433 L440 V474 F478W375-I379 WeakPolarHBondContact O-CG1 3.33Å; W375-I379 PolarHBondContact O-N 3.42Å; W375-I379 VanDerWaalsContact O-N 3.13Å; L376-I379 PolarHBondContact O-N 3.34Å; M377-I379 PolarHBondContact O-N 3.19Å; I379-T381 PolarHBondContact O-N 3.47Å; I379-E382 PolarHBondContact O-N 3.13Å; I379-L383 HydrophobicContact CG2-CD1 3.95Å; I379-L383 HydrophobicContact CG2-CG 4.31Å; I379-L383 WeakPolarHBondContact O-CG 3.49Å; I379-L383 PolarHBondContact O-N 3.29Å; I379-I433 HydrophobicContact CG2-CG1 4.47Å; I379-L440 HydrophobicContact CD1-CD1 3.44Å; I379-L440 VanDerWaalsContact CD1-CD1 3.44Å; I379-V474 HydrophobicContact CB-CG1 4.24Å; I379-V474 HydrophobicContact CG2-CG1 3.78Å; I379-V474 HydrophobicContact CG2-CG2 4.32Å; I379-F478 HydrophobicContact CD1-CE1 4.24Å; I379-F478 HydrophobicContact CD1-CZ 3.91Å; I379-F478 HydrophobicContact CG2-CE1 4.47Å
380S83.6Confident76.7Confident23 Ų2372.9 Ų72.916%0.16138%0.375CS..Hα-helixtrans-58.1-47.5176.6-165.90000111.7L376 M377 L378 E382 L383 E384L376-S380 WeakPolarHBondContact O-CB 3.5Å; L376-S380 PolarHBondContact O-N 3.44Å; M377-S380 WeakPolarHBondContact O-CB 3.32Å; M377-S380 PolarHBondContact O-N 3.36Å; L378-S380 VanDerWaalsContact C-N 3.35Å; L378-S380 PolarHBondContact O-N 2.93Å; S380-E382 PolarHBondContact O-N 3.38Å; S380-L383 PolarHBondContact O-N 3.13Å; S380-E384 PolarHBondContact O-N 3.08Å; S380-E384 VanDerWaalsContact O-N 3.12Å
381T81.4Confident74.5Confident70 Ų7073 Ų7343%0.42939%0.388SS..Hα-helixtrans-62.3-32.1179.156.60000112.8M377 L378 I379 R385M377-T381 WeakPolarHBondContact O-CG2 3.46Å; M377-T381 PolarHBondContact O-N 2.99Å; M377-T381 PolarHBondContact O-OG1 2.97Å; L378-T381 PolarHBondContact O-N 3.49Å; L378-T381 PolarHBondContact O-OG1 2.94Å; I379-T381 PolarHBondContact O-N 3.47Å; T381-R385 WeakPolarHBondContact O-CG 3.5Å; T381-R385 PolarHBondContact O-N 3.07Å
382E71.9Confident72.3Confident36 Ų3674.3 Ų74.317%0.16840%0.398CS..Hα-helixtrans-78.5-38.9179.3-168.754.2-146.400112.4L378 I379 S380 E384 R385 S386 I399L378-E382 PolarHBondContact O-N 2.86Å; L378-E382 VanDerWaalsContact O-N 3.15Å; I379-E382 PolarHBondContact O-N 3.13Å; S380-E382 PolarHBondContact O-N 3.38Å; E382-E384 PolarHBondContact O-N 2.64Å; E382-R385 WeakPolarHBondContact O-CB 3.3Å; E382-R385 PolarHBondContact O-N 3.45Å; E382-S386 PolarHBondContact O-N 3.43Å; E382-I399 HydrophobicContact CG-CD1 4.05Å; E382-I399 HydrophobicContact CG-CG1 4.16Å
383L75.6Confident70Confident37 Ų3780.3 Ų80.319%0.19444%0.44CS..Hα-helixtrans-57.7-39.8172-72.1169.9000111.3I379 S380 R385 T387 I433 V474 C477I379-L383 HydrophobicContact CG2-CD1 3.95Å; I379-L383 HydrophobicContact CG2-CG 4.31Å; I379-L383 WeakPolarHBondContact O-CG 3.49Å; I379-L383 PolarHBondContact O-N 3.29Å; S380-L383 PolarHBondContact O-N 3.13Å; L383-R385 VanDerWaalsContact C-N 3.34Å; L383-R385 PolarHBondContact O-N 3.14Å; L383-T387 WeakPolarHBondContact O-CG2 3.35Å; L383-T387 PolarHBondContact O-N 3.47Å; L383-T387 VanDerWaalsContact O-N 3.13Å; L383-T387 PolarHBondContact O-OG1 2.96Å; L383-I433 HydrophobicContact CD2-CD1 4.01Å; L383-V474 HydrophobicContact CD1-CG2 4.23Å; L383-C477 HydrophobicContact CD1-CB 4.08Å
384E74.1Confident67.8Low98 Ų9881.4 Ų81.446%0.45845%0.45SS..Hα-helixtrans-66.5-30.1173.2-73.9-173.5-15300113.9S380 E382 T387 K388S380-E384 PolarHBondContact O-N 3.08Å; S380-E384 VanDerWaalsContact O-N 3.12Å; E382-E384 PolarHBondContact O-N 2.64Å; E384-T387 WeakPolarHBondContact CA-OG1 3.5Å; E384-T387 PolarHBondContact O-OG1 3.24Å; E384-K388 WeakPolarHBondContact O-CD 3.22Å; E384-K388 VanDerWaalsContact O-CG 3.28Å; E384-K388 WeakPolarHBondContact O-CG 3.33Å; E384-K388 PolarHBondContact O-N 3.19Å; E384-K388 IonicContact OE2-NZ 3.59Å
385R69.8Low65.7Low165 Ų16577.2 Ų77.262%0.62344%0.435SS*.Hα-helixtrans-75.7-41.8176.1-73.5175.992.4131.70.5111.6T381 E382 L383 T387 K388 N389T381-R385 WeakPolarHBondContact O-CG 3.5Å; T381-R385 PolarHBondContact O-N 3.07Å; E382-R385 WeakPolarHBondContact O-CB 3.3Å; E382-R385 PolarHBondContact O-N 3.45Å; L383-R385 VanDerWaalsContact C-N 3.34Å; L383-R385 PolarHBondContact O-N 3.14Å; R385-T387 PolarHBondContact O-N 3.27Å; R385-K388 PolarHBondContact O-N 3.37Å; R385-N389 PolarHBondContact O-N 3.39Å; R385-N389 VanDerWaalsContact O-N 3.14Å
386S60.3Low63.7Low66 Ų6677.6 Ų77.646%0.46245%0.446SS..Hα-helixtrans-63.9-38.5178.1177.80000112.5E382 K388E382-S386 PolarHBondContact O-N 3.43Å; S386-K388 VanDerWaalsContact C-N 3.32Å; S386-K388 PolarHBondContact O-N 2.93Å
387T58.6Low61.7Low112 Ų11281.5 Ų81.569%0.68747%0.473SS*.Hα-helixtrans-68.7-2817645.30000113.2L383 E384 R385L383-T387 WeakPolarHBondContact O-CG2 3.35Å; L383-T387 PolarHBondContact O-N 3.47Å; L383-T387 VanDerWaalsContact O-N 3.13Å; L383-T387 PolarHBondContact O-OG1 2.96Å; E384-T387 WeakPolarHBondContact CA-OG1 3.5Å; E384-T387 PolarHBondContact O-OG1 3.24Å; R385-T387 PolarHBondContact O-N 3.27Å
388K57.1Low59.9Low146 Ų14682.8 Ų82.864%0.63548%0.478SS*.Hα-helixtrans-85.9-22.5179.3-70.7170.2-172.3157.90113.9E384 R385 S386E384-K388 WeakPolarHBondContact O-CD 3.22Å; E384-K388 VanDerWaalsContact O-CG 3.28Å; E384-K388 WeakPolarHBondContact O-CG 3.33Å; E384-K388 PolarHBondContact O-N 3.19Å; E384-K388 IonicContact OE2-NZ 3.59Å; R385-K388 PolarHBondContact O-N 3.37Å; S386-K388 VanDerWaalsContact C-N 3.32Å; S386-K388 PolarHBondContact O-N 2.93Å
389N50Low58.3Low108 Ų10879.8 Ų79.858%0.57846%0.462SS*.  trans-138.491.3-178.7-77-33.4000112.4R385 S391R385-N389 PolarHBondContact O-N 3.39Å; R385-N389 VanDerWaalsContact O-N 3.14Å; N389-S391 VanDerWaalsContact C-N 3.27Å; N389-S391 PolarHBondContact O-N 2.98Å
390P50.3Low56.5Low124 Ų12480.8 Ų80.881%0.80547%0.472SS*.THydrogen-bonded Turntrans-74.8-7.7-176.1-14.529.4000115.1
391S43.9Very low54.9Low116 Ų11682.1 Ų82.181%0.81148%0.482SS*.THydrogen-bonded Turntrans-103.711.5-165.459.30000115.9N389N389-S391 VanDerWaalsContact C-N 3.27Å; N389-S391 PolarHBondContact O-N 2.98Å
392S43.7Very low53.4Low58 Ų5883.9 Ų83.941%0.40649%0.488SS..  trans-115.2101.8175.759.90000111.4S394S392-S394 PolarHBondContact O-N 2.84Å
393S41.9Very low52.3Low126 Ų12683.5 Ų83.588%0.88149%0.487SS*.THydrogen-bonded Turntrans-70.223.7172.358.90000113.9
394S43.9Very low50.8Low61 Ų6186.7 Ų86.743%0.42750%0.504SS..THydrogen-bonded Turntrans-106.1-4.4-177.259.50000113.9S392 S397S392-S394 PolarHBondContact O-N 2.84Å; S394-S397 WeakPolarHBondContact O-CB 3.44Å; S394-S397 PolarHBondContact O-N 2.88Å
395S45.3Very low49.4Very low40 Ų4090 Ų9028%0.2852%0.516SS..Hα-helixtrans-67.1-36.9-172.450.60000114S397 E398S395-S397 VanDerWaalsContact C-N 3.27Å; S395-S397 PolarHBondContact O-N 3.49Å; S395-E398 PolarHBondContact O-N 3.38Å
396S44.7Very low48.1Very low62 Ų6290 Ų9043%0.43452%0.524SS..Hα-helixtrans-65-29.6176.2480000113.1A400S396-A400 PolarHBondContact O-N 2.84Å
397S45.8Very low47.2Very low81 Ų8197 Ų9757%0.56654%0.54SS*.Hα-helixtrans-71.6-30.7178.1-176.90000112.9S394 S395 S401S394-S397 WeakPolarHBondContact O-CB 3.44Å; S394-S397 PolarHBondContact O-N 2.88Å; S395-S397 VanDerWaalsContact C-N 3.27Å; S395-S397 PolarHBondContact O-N 3.49Å; S397-S401 VanDerWaalsContact O-CB 3.29Å; S397-S401 WeakPolarHBondContact O-CB 3.46Å; S397-S401 PolarHBondContact O-N 3.21Å; S397-S401 PolarHBondContact O-OG 3.21Å
398E49Very low46.1Very low103 Ų103100.4 Ų100.448%0.48155%0.548SS..Hα-helixtrans-77.3-38.8-179-75.2-175.7173.300111.6S395 S401 L402S395-E398 PolarHBondContact O-N 3.38Å; E398-S401 WeakPolarHBondContact CA-OG 3.34Å; E398-S401 PolarHBondContact O-N 3.31Å; E398-S401 PolarHBondContact O-OG 3.13Å; E398-L402 PolarHBondContact O-N 3.4Å
399I50Low44.9Very low30 Ų3098.5 Ų98.515%0.15455%0.553CS.*Hα-helixtrans-62.7-47.1174.6-52.3174.1000110.1E382 S401 L402 L403 V432 I433E382-I399 HydrophobicContact CG-CD1 4.05Å; E382-I399 HydrophobicContact CG-CG1 4.16Å; I399-S401 VanDerWaalsContact C-N 3.31Å; I399-S401 PolarHBondContact O-N 3.35Å; I399-L402 PolarHBondContact O-N 2.89Å; I399-L403 HydrophobicContact CG2-CD1 3.73Å; I399-L403 WeakPolarHBondContact O-CB 3.49Å; I399-L403 WeakPolarHBondContact O-CD1 3.39Å; I399-L403 WeakPolarHBondContact O-CG 3.47Å; I399-L403 PolarHBondContact O-N 3.18Å; I399-V432 HydrophobicContact CB-CB 4.14Å; I399-V432 HydrophobicContact CB-CG1 4.03Å; I399-V432 HydrophobicContact CB-CG2 4.37Å; I399-V432 HydrophobicContact CG2-CB 3.85Å; I399-V432 HydrophobicContact CG2-CG1 3.37Å; I399-I433 HydrophobicContact CD1-CD1 4.44Å; I399-I433 HydrophobicContact CD1-CG1 4.28Å
400A46.1Very low43.8Very low34 Ų34100 Ų10028%0.28156%0.561SS.*Hα-helixtrans-60.5-39.217400000112S396 L404 V432S396-A400 PolarHBondContact O-N 2.84Å; A400-L404 WeakPolarHBondContact O-CB 3.4Å; A400-L404 WeakPolarHBondContact O-CD1 3.49Å; A400-L404 WeakPolarHBondContact O-CG 3.39Å; A400-L404 PolarHBondContact O-N 3.39Å; A400-V432 HydrophobicContact CB-CG2 4.48Å
401S49Very low42.9Very low51 Ų51100.7 Ų100.736%0.35757%0.565SS.*Hα-helixtrans-69.9-33.4178.479.50000113.8S397 E398 I399 K405S397-S401 VanDerWaalsContact O-CB 3.29Å; S397-S401 WeakPolarHBondContact O-CB 3.46Å; S397-S401 PolarHBondContact O-N 3.21Å; S397-S401 PolarHBondContact O-OG 3.21Å; E398-S401 WeakPolarHBondContact CA-OG 3.34Å; E398-S401 PolarHBondContact O-N 3.31Å; E398-S401 PolarHBondContact O-OG 3.13Å; I399-S401 VanDerWaalsContact C-N 3.31Å; I399-S401 PolarHBondContact O-N 3.35Å; S401-K405 WeakPolarHBondContact O-CB 3.43Å; S401-K405 PolarHBondContact O-N 2.87Å
402L50.5Low42.3Very low107 Ų107100.1 Ų100.156%0.5656%0.562SS**Hα-helixtrans-72.1-42.1173.9-83.9162.5000111.4E398 I399 L404 K405E398-L402 PolarHBondContact O-N 3.4Å; I399-L402 PolarHBondContact O-N 2.89Å; L402-L404 VanDerWaalsContact C-N 3.28Å; L402-L404 PolarHBondContact O-N 3.11Å; L402-K405 PolarHBondContact O-N 2.87Å
403L48.1Very low41.5Very low29 Ų29102.3 Ų102.315%0.15258%0.577CS.*Hα-helixtrans-63.9-32.4173-77.7154.1000112.4L314 W375 I399 V432 T436L314-L403 HydrophobicContact CD1-CB 3.84Å; L314-L403 HydrophobicContact CD1-CD1 3.97Å; L314-L403 HydrophobicContact CD1-CD2 3.94Å; L314-L403 HydrophobicContact CD1-CG 4.15Å; L314-L403 HydrophobicContact CG-CD2 4.01Å; W375-L403 HydrophobicContact CH2-CD2 3.1Å; W375-L403 HydrophobicContact CH2-CG 3.73Å; W375-L403 HydrophobicContact CZ2-CD2 3.96Å; W375-L403 HydrophobicContact CZ3-CD2 3.44Å; W375-L403 VanDerWaalsContact CZ3-CD2 3.44Å; W375-L403 HydrophobicContact CZ3-CG 3.91Å; I399-L403 HydrophobicContact CG2-CD1 3.73Å; I399-L403 WeakPolarHBondContact O-CB 3.49Å; I399-L403 WeakPolarHBondContact O-CD1 3.39Å; I399-L403 WeakPolarHBondContact O-CG 3.47Å; I399-L403 PolarHBondContact O-N 3.18Å; L403-V432 HydrophobicContact CD1-CG1 3.33Å; L403-T436 HydrophobicContact CD1-CG2 4.23Å; L403-T436 HydrophobicContact CD2-CG2 4.36Å
404L45.8Very low40.8Very low104 Ų104104.3 Ų104.355%0.54558%0.578SS.*Hα-helixtrans-85.8-21.7176.1-74.1163.9000113.7A400 L402 Q406 R407A400-L404 WeakPolarHBondContact O-CB 3.4Å; A400-L404 WeakPolarHBondContact O-CD1 3.49Å; A400-L404 WeakPolarHBondContact O-CG 3.39Å; A400-L404 PolarHBondContact O-N 3.39Å; L402-L404 VanDerWaalsContact C-N 3.28Å; L402-L404 PolarHBondContact O-N 3.11Å; L404-Q406 VanDerWaalsContact C-N 3.29Å; L404-Q406 PolarHBondContact O-N 2.94Å; L404-R407 WeakPolarHBondContact O-CB 3.42Å; L404-R407 PolarHBondContact O-N 3.23Å
405K44.6Very low40Very low166 Ų166107 Ų10772%0.72259%0.592SS**G310 helixtrans-71.9-12.2-175-114.2177.8175.5174.50115.4S401 L402 R407S401-K405 WeakPolarHBondContact O-CB 3.43Å; S401-K405 PolarHBondContact O-N 2.87Å; L402-K405 PolarHBondContact O-N 2.87Å; K405-R407 PolarHBondContact O-N 3.48Å
406Q42.1Very low39.2Very low167 Ų167111.4 Ų111.478%0.7862%0.619SS**G310 helixtrans-75.811.3168.1-79.4-168-500113.5L404 E408L404-Q406 VanDerWaalsContact C-N 3.29Å; L404-Q406 PolarHBondContact O-N 2.94Å; Q406-E408 VanDerWaalsContact C-N 3.3Å; Q406-E408 PolarHBondContact O-N 2.77Å
407R41.4Very low38.2Very low213 Ų213113.6 Ų113.680%0.80463%0.63SS**G310 helixtrans-71.6-15.3172-116.5176.7172.9178.1-1.3115.1L404 K405L404-R407 WeakPolarHBondContact O-CB 3.42Å; L404-R407 PolarHBondContact O-N 3.23Å; K405-R407 PolarHBondContact O-N 3.48Å
408E34.8Very low37.4Very low182 Ų182118.8 Ų118.885%0.8565%0.651SS**  trans-11769.5-168.9-68.2-173.817200112.4Q406Q406-E408 VanDerWaalsContact C-N 3.3Å; Q406-E408 PolarHBondContact O-N 2.77Å
409S31.3Very low36.3Very low106 Ų106118 Ų11874%0.74166%0.657SS**SBendtrans-146.542.5159.262.80000113.2
410D27.6Very low35.2Very low141 Ų141124.7 Ų124.775%0.75469%0.692SS**  trans-137.7103.8161.5-103.2-28.3000110.7S412D410-S412 PolarHBondContact O-N 3.21Å
411P31.1Very low34.4Very low137 Ų137131.5 Ų131.589%0.8972%0.723SS**  trans-83.840.7-176.534.5-34.1000112.7
412S31.6Very low33.4Very low105 Ų105138.6 Ų138.673%0.73475%0.75SS**  trans-146.247.7-179.9680000115.4D410D410-S412 PolarHBondContact O-N 3.21Å
413S26.5Very low32.4Very low103 Ų103137 Ų13772%0.7276%0.76SS**  trans-150.1108.1151.865.40000111.3T415S413-T415 PolarHBondContact O-N 3Å
414N27.4Very low31.5Very low169 Ų169143.5 Ų143.590%0.90479%0.79SS**  trans-81.9105166.6-92.6-17.5000107.9
415T26.4Very low30.7Very low118 Ų118143 Ų14372%0.72480%0.8SS**  trans-171.8129.514813.30000110.5S413S413-T415 PolarHBondContact O-N 3Å
416P28.5Very low30.2Very low131 Ų131145.2 Ų145.285%0.85181%0.805SS**  trans-86.5117.5174.533-26.6000108.9
417T24.8Very low29.6Very low109 Ų109141.7 Ų141.767%0.66980%0.795SS**  trans-135.891.8168.1-16.30000110.4S419T417-S419 WeakPolarHBondContact CG2-OG 3.44Å; T417-S419 PolarHBondContact O-N 3.44Å
418L28.5Very low29Very low189 Ų189139 Ų13999%0.9980%0.797SS**  trans-76.882.6158.1-108.9122.7000107.5
419S26.8Very low29.3Very low88 Ų88133.8 Ų133.862%0.61579%0.792SS**  trans-167.235.4171.159.10000116.3T417T417-S419 WeakPolarHBondContact CG2-OG 3.44Å; T417-S419 PolarHBondContact O-N 3.44Å
420L26.1Very low30Very low169 Ų169134.9 Ų134.989%0.88579%0.785SS**  trans-140.346.5173.1-80.2172000113.2
421L29.9Very low31.8Very low178 Ų178130.7 Ų130.793%0.93276%0.763SS**  trans-120.151.3163.6-79.5168.4000109.9
422E28.4Very low33.3Very low199 Ų199125 Ų12593%0.9373%0.726SS**  trans-117.991.4162.8-72-176.4170.300106.3
423G28.5Very low35.1Very low75 Ų75120.4 Ų120.477%0.77369%0.693SS**SBendtrans-172.9-29.6-178.600000116.1
424E29.9Very low37.1Very low165 Ų165117.6 Ų117.677%0.77167%0.673SS**SBendtrans-127.8123.8165.9-71.1-176.5172.100107.1Y426E424-Y426 PolarHBondContact O-N 3.09Å; E424-Y426 VanDerWaalsContact O-N 3.07Å
425A29.4Very low39Very low92 Ų92114.1 Ų114.176%0.7665%0.653SS**  trans-57.3114.2-172.900000110.3V427A425-V427 VanDerWaalsContact C-N 3.29Å; A425-V427 HydrophobicContact CB-CG2 4.42Å; A425-V427 PolarHBondContact O-N 2.96Å
426Y32.1Very low41.4Very low213 Ų213109 Ų10984%0.83562%0.621SS**  trans-65.994.4162.9-157.9-93.3000106.8E424 D428E424-Y426 PolarHBondContact O-N 3.09Å; E424-Y426 VanDerWaalsContact O-N 3.07Å; Y426-D428 PolarHBondContact O-N 3.02Å
427V30.9Very low44Very low94 Ų94102.9 Ų102.957%0.5758%0.581SS**  trans-80.1114.8169.1-177.10000106.2A425 G429A425-V427 VanDerWaalsContact C-N 3.29Å; A425-V427 HydrophobicContact CB-CG2 4.42Å; A425-V427 PolarHBondContact O-N 2.96Å; V427-G429 PolarHBondContact O-N 2.73Å
428D29.2Very low46.8Very low155 Ų15599.8 Ų99.883%0.82956%0.561SS**THydrogen-bonded Turntrans-52.4109.6179.6-147.47.8000109.7Y426Y426-D428 PolarHBondContact O-N 3.02Å
429G40.5Very low49.6Very low73 Ų7392 Ų9275%0.75352%0.518SS*.THydrogen-bonded Turntrans116.53.1172.500000119.2V427V427-G429 PolarHBondContact O-N 2.73Å
430E46.5Very low52.7Low129 Ų12988 Ų8860%0.60349%0.49SS*.  trans-73.6128.5173.9-76.7-166.8165.400112.8
431D63.8Low55.7Low54 Ų5479.9 Ų79.929%0.28945%0.448SS..  trans-66.4132176.4-170-34.5000110.6I433 S434 M435 R481D431-I433 PolarHBondContact O-N 3.12Å; D431-I433 VanDerWaalsContact O-N 3.1Å; D431-I433 WeakPolarHBondContact OD1-CB 3.5Å; D431-I433 PolarHBondContact OD1-N 3.26Å; D431-S434 WeakPolarHBondContact O-CA 3.32Å; D431-S434 VanDerWaalsContact O-CB 3.31Å; D431-S434 WeakPolarHBondContact O-CB 3.22Å; D431-S434 PolarHBondContact O-N 3.13Å; D431-M435 PolarHBondContact O-N 3.44Å; D431-R481 IonicContact OD1-NH1 3.4Å; D431-R481 PolarHBondContact OD1-NH1 3.48Å; D431-R481 IonicContact OD2-CZ 3.43Å; D431-R481 IonicContact OD2-NH1 2.77Å; D431-R481 PolarHBondContact OD2-NH1 3.39Å; D431-R481 IonicContact OD2-NH2 3.46Å; D431-R481 PolarHBondContact OD2-NH2 2.97Å
432V63.1Low58.6Low17 Ų1771.4 Ų71.410%0.10340%0.403CS..Hα-helixtrans-55.6-30.1-179.9-175.10000112.4I399 A400 L403 S434 M435 T436I399-V432 HydrophobicContact CB-CB 4.14Å; I399-V432 HydrophobicContact CB-CG1 4.03Å; I399-V432 HydrophobicContact CB-CG2 4.37Å; I399-V432 HydrophobicContact CG2-CB 3.85Å; I399-V432 HydrophobicContact CG2-CG1 3.37Å; A400-V432 HydrophobicContact CB-CG2 4.48Å; L403-V432 HydrophobicContact CD1-CG1 3.33Å; V432-S434 VanDerWaalsContact C-N 3.35Å; V432-M435 PolarHBondContact O-N 2.9Å; V432-T436 PolarHBondContact O-N 3.1Å; V432-T436 VanDerWaalsContact O-N 3.15Å; V432-T436 PolarHBondContact O-OG1 3.35Å
433I68.8Low61.6Low9 Ų962 Ų625%0.04636%0.359CS..Hα-helixtrans-65.6-39.1174-66.3167.8000110.5I379 L383 I399 D431 T436 A437 F478I379-I433 HydrophobicContact CG2-CG1 4.47Å; L383-I433 HydrophobicContact CD2-CD1 4.01Å; I399-I433 HydrophobicContact CD1-CD1 4.44Å; I399-I433 HydrophobicContact CD1-CG1 4.28Å; D431-I433 PolarHBondContact O-N 3.12Å; D431-I433 VanDerWaalsContact O-N 3.1Å; D431-I433 WeakPolarHBondContact OD1-CB 3.5Å; D431-I433 PolarHBondContact OD1-N 3.26Å; I433-T436 PolarHBondContact O-N 3.38Å; I433-T436 PolarHBondContact O-OG1 2.87Å; I433-A437 VanDerWaalsContact O-CB 3.23Å; I433-A437 WeakPolarHBondContact O-CB 3.26Å; I433-A437 PolarHBondContact O-N 3.33Å; I433-F478 HydrophobicContact CG2-CD1 4.11Å; I433-F478 HydrophobicContact CG2-CE1 3.9Å
434S68.8Low64.7Low44 Ų4458.4 Ų58.431%0.30832%0.322SS..Hα-helixtrans-67.5-37.4177.6-60.50000111.6D431 V432 T436D431-S434 WeakPolarHBondContact O-CA 3.32Å; D431-S434 VanDerWaalsContact O-CB 3.31Å; D431-S434 WeakPolarHBondContact O-CB 3.22Å; D431-S434 PolarHBondContact O-N 3.13Å; V432-S434 VanDerWaalsContact C-N 3.35Å; S434-T436 VanDerWaalsContact C-N 3.33Å; S434-T436 PolarHBondContact O-N 3.28Å
435M67.3Low67.7Low96 Ų9651.6 Ų51.647%0.47329%0.291SS..Hα-helixtrans-66.7-31.8175.7-62.6-175.276.300113.2D431 V432D431-M435 PolarHBondContact O-N 3.44Å; V432-M435 PolarHBondContact O-N 2.9Å
436T77.5Confident70.7Confident10 Ų1047.2 Ų47.26%0.06125%0.254CS..Hα-helixtrans-94.5-22.1-177.951.20000113.4L314 L403 V432 I433 S434 N438 R439 L440L314-T436 HydrophobicContact CD2-CG2 3.79Å; L403-T436 HydrophobicContact CD1-CG2 4.23Å; L403-T436 HydrophobicContact CD2-CG2 4.36Å; V432-T436 PolarHBondContact O-N 3.1Å; V432-T436 VanDerWaalsContact O-N 3.15Å; V432-T436 PolarHBondContact O-OG1 3.35Å; I433-T436 PolarHBondContact O-N 3.38Å; I433-T436 PolarHBondContact O-OG1 2.87Å; S434-T436 VanDerWaalsContact C-N 3.33Å; S434-T436 PolarHBondContact O-N 3.28Å; T436-N438 PolarHBondContact O-N 3.48Å; T436-R439 WeakPolarHBondContact O-CB 3.41Å; T436-R439 PolarHBondContact O-N 2.97Å; T436-R439 VanDerWaalsContact O-N 3.16Å; T436-L440 WeakPolarHBondContact O-CG 3.1Å; T436-L440 PolarHBondContact O-N 3.2Å
437A82.8Confident73.6Confident2 Ų237.3 Ų37.32%0.01722%0.216CC..Hα-helixtrans-55.3-47.2-177.400000112.7I433 R439 L440 S441 F478 I485I433-A437 VanDerWaalsContact O-CB 3.23Å; I433-A437 WeakPolarHBondContact O-CB 3.26Å; I433-A437 PolarHBondContact O-N 3.33Å; A437-R439 PolarHBondContact O-N 3.2Å; A437-L440 PolarHBondContact O-N 3.41Å; A437-S441 WeakPolarHBondContact O-CB 3.28Å; A437-S441 PolarHBondContact O-N 3.02Å; A437-S441 PolarHBondContact O-OG 3.37Å; A437-F478 HydrophobicContact CB-CB 4.27Å; A437-F478 HydrophobicContact CB-CD1 3.8Å; A437-F478 HydrophobicContact CB-CD2 4.15Å; A437-F478 HydrophobicContact CB-CE1 4.14Å; A437-F478 HydrophobicContact CB-CE2 4.47Å; A437-F478 HydrophobicContact CB-CG 3.81Å; A437-F478 HydrophobicContact CB-CZ 4.47Å; A437-I485 HydrophobicContact CB-CD1 3.89Å
438N83.2Confident76.4Confident45 Ų4533.9 Ų33.924%0.24119%0.193CC..Hα-helixtrans-63.5-41.1179.6-73-26.1000112.4Y318 T436 S441 A442 N482 I485Y318-N438 HydrophobicContact CE1-CB 4.3Å; Y318-N438 HydrophobicContact CE2-CB 3.79Å; Y318-N438 WeakPolarHBondContact CE2-O 3.39Å; T436-N438 PolarHBondContact O-N 3.48Å; N438-S441 PolarHBondContact O-N 2.75Å; N438-A442 PolarHBondContact O-N 3.35Å; N438-A442 VanDerWaalsContact O-N 3.14Å; N438-N482 PolarHBondContact OD1-ND2 3.47Å; N438-I485 WeakPolarHBondContact OD1-CG1 3.27Å
439R88.9Confident79.2Confident24 Ų2428 Ų289%0.09116%0.16CC..Hα-helixtrans-64-50.3177.8-71.4168.4-179.4-85.5-0.8111.2L311 S313 S316 Y318 T436 A437 S441 A442 V443L311-R439 HydrophobicContact CD1-CG 4.24Å; L311-R439 HydrophobicContact CG-CB 4.17Å; L311-R439 HydrophobicContact CG-CG 4.37Å; L311-R439 WeakPolarHBondContact O-CB 3.38Å; L311-R439 WeakPolarHBondContact O-CD 3.42Å; L311-R439 PolarHBondContact O-NH1 3.38Å; S313-R439 PolarHBondContact O-NH1 3.47Å; S316-R439 PolarHBondContact O-NH1 3.3Å; S316-R439 PolarHBondContact O-NH2 2.76Å; S316-R439 PolarHBondContact OG-NH1 3.13Å; S316-R439 VanDerWaalsContact OG-NH1 3.08Å; Y318-R439 HydrophobicContact CD2-CB 4.45Å; Y318-R439 HydrophobicContact CD2-CG 3.62Å; Y318-R439 HydrophobicContact CE2-CG 4.39Å; Y318-R439 HydrophobicContact CG-CG 4.37Å; T436-R439 WeakPolarHBondContact O-CB 3.41Å; T436-R439 PolarHBondContact O-N 2.97Å; T436-R439 VanDerWaalsContact O-N 3.16Å; A437-R439 PolarHBondContact O-N 3.2Å; R439-S441 VanDerWaalsContact C-N 3.32Å; R439-S441 PolarHBondContact O-N 2.73Å; R439-A442 PolarHBondContact O-N 2.95Å; R439-V443 PolarHBondContact O-N 3.38Å
440L90.3Very high81.5Confident4 Ų424.5 Ų24.52%0.02113%0.125CC..Hα-helixtrans-63.9-39.4178.6-69.4168.1000111.3L312 L372 W375 L376 I379 T436 A437 A442 V443 I444 F478L312-L440 HydrophobicContact CD2-CD2 3.42Å; L312-L440 VanDerWaalsContact CD2-CD2 3.42Å; L372-L440 HydrophobicContact CD1-CD2 3.83Å; W375-L440 HydrophobicContact CB-CD2 3.92Å; W375-L440 HydrophobicContact CG-CD2 4.27Å; L376-L440 HydrophobicContact CD2-CD1 4.45Å; I379-L440 HydrophobicContact CD1-CD1 3.44Å; I379-L440 VanDerWaalsContact CD1-CD1 3.44Å; T436-L440 WeakPolarHBondContact O-CG 3.1Å; T436-L440 PolarHBondContact O-N 3.2Å; A437-L440 PolarHBondContact O-N 3.41Å; L440-A442 VanDerWaalsContact C-N 3.33Å; L440-A442 PolarHBondContact O-N 3.2Å; L440-V443 PolarHBondContact O-N 2.92Å; L440-V443 VanDerWaalsContact O-N 3.12Å; L440-I444 VanDerWaalsContact O-CG1 3.28Å; L440-I444 WeakPolarHBondContact O-CG1 3.39Å; L440-I444 PolarHBondContact O-N 3.13Å; L440-F478 HydrophobicContact CB-CE2 3.88Å; L440-F478 HydrophobicContact CB-CZ 4.29Å; L440-F478 HydrophobicContact CD1-CE2 4.14Å; L440-F478 HydrophobicContact CD1-CZ 3.67Å
441S90.4Very high83.4Confident0 Ų018.6 Ų18.60%010%0.097CC..Hα-helixtrans-62.1-39.1178.8-60.90000112.5A437 N438 R439 I444 Q445 I485 F490A437-S441 WeakPolarHBondContact O-CB 3.28Å; A437-S441 PolarHBondContact O-N 3.02Å; A437-S441 PolarHBondContact O-OG 3.37Å; N438-S441 PolarHBondContact O-N 2.75Å; R439-S441 VanDerWaalsContact C-N 3.32Å; R439-S441 PolarHBondContact O-N 2.73Å; S441-I444 PolarHBondContact O-N 3.09Å; S441-Q445 WeakPolarHBondContact O-CB 3.25Å; S441-Q445 PolarHBondContact O-N 3.18Å; S441-I485 WeakPolarHBondContact OG-CG2 3.4Å; S441-F490 WeakPolarHBondContact OG-CZ 3.36Å
442A90Very high84.4Confident0 Ų016.9 Ų16.90%09%0.09CC..Hα-helixtrans-65.1-37173.700000112.9L311 M322 N438 R439 L440 Q445 A446L311-A442 HydrophobicContact CD2-CB 3.65Å; M322-A442 HydrophobicContact CB-CB 4.37Å; M322-A442 HydrophobicContact CG-CB 3.79Å; N438-A442 PolarHBondContact O-N 3.35Å; N438-A442 VanDerWaalsContact O-N 3.14Å; R439-A442 PolarHBondContact O-N 2.95Å; L440-A442 VanDerWaalsContact C-N 3.33Å; L440-A442 PolarHBondContact O-N 3.2Å; A442-Q445 PolarHBondContact O-N 2.71Å; A442-A446 PolarHBondContact O-N 3.47Å
443V92.4Very high85.4Confident0 Ų016.4 Ų16.40%09%0.087CC..Hα-helixtrans-69.8-38.8173.8-172.50000111.3L311 L312 L325 L368 W369 L372 R439 L440 Q445 A446 F447L311-V443 HydrophobicContact CB-CG2 4.37Å; L311-V443 HydrophobicContact CD2-CG2 3.87Å; L311-V443 HydrophobicContact CG-CG2 4.42Å; L312-V443 HydrophobicContact CD2-CG2 3.96Å; L312-V443 HydrophobicContact CG-CG2 4.32Å; L325-V443 HydrophobicContact CD2-CG2 4.19Å; L368-V443 HydrophobicContact CD1-CG1 4.1Å; L368-V443 HydrophobicContact CD2-CG1 4.07Å; L368-V443 HydrophobicContact CG-CG1 3.97Å; W369-V443 HydrophobicContact CE3-CG1 4.42Å; W369-V443 HydrophobicContact CZ3-CG1 4Å; L372-V443 HydrophobicContact CB-CG1 4.37Å; L372-V443 HydrophobicContact CD1-CB 4.31Å; L372-V443 HydrophobicContact CD1-CG1 4.31Å; L372-V443 HydrophobicContact CD2-CG1 4.09Å; L372-V443 HydrophobicContact CG-CG1 4.49Å; R439-V443 PolarHBondContact O-N 3.38Å; L440-V443 PolarHBondContact O-N 2.92Å; L440-V443 VanDerWaalsContact O-N 3.12Å; V443-Q445 VanDerWaalsContact C-N 3.33Å; V443-Q445 PolarHBondContact O-N 2.9Å; V443-A446 WeakPolarHBondContact O-CB 3.44Å; V443-A446 PolarHBondContact O-N 3.02Å; V443-F447 PolarHBondContact O-N 2.77Å
444I93.3Very high86.1Confident0 Ų020 Ų200%010%0.104CC..Hα-helixtrans-61.4-42.3173.6-67.1159.1000110.6L372 L376 L440 S441 A446 F447 Y448 F464 F467 L475 F490 F492L372-I444 HydrophobicContact CD1-CG1 4.03Å; L372-I444 HydrophobicContact CD2-CG1 3.83Å; L372-I444 HydrophobicContact CG-CG1 4.43Å; L376-I444 HydrophobicContact CD1-CD1 4.29Å; L376-I444 HydrophobicContact CD2-CD1 4.4Å; L440-I444 VanDerWaalsContact O-CG1 3.28Å; L440-I444 WeakPolarHBondContact O-CG1 3.39Å; L440-I444 PolarHBondContact O-N 3.13Å; S441-I444 PolarHBondContact O-N 3.09Å; I444-A446 PolarHBondContact O-N 3.33Å; I444-F447 WeakPolarHBondContact O-CB 3.4Å; I444-F447 PolarHBondContact O-N 3.4Å; I444-Y448 PolarHBondContact O-N 3.16Å; I444-F464 HydrophobicContact CG2-CE2 4.36Å; I444-F464 HydrophobicContact CG2-CZ 4.24Å; I444-F467 HydrophobicContact CG1-CE1 4.3Å; I444-F467 HydrophobicContact CG1-CZ 4.35Å; I444-F467 HydrophobicContact CG2-CE1 4.26Å; I444-L475 HydrophobicContact CD1-CD2 3.73Å; I444-F490 HydrophobicContact CB-CE1 3.98Å; I444-F490 HydrophobicContact CD1-CE1 3.99Å; I444-F490 HydrophobicContact CD1-CZ 3.87Å; I444-F490 HydrophobicContact CG2-CD1 4.38Å; I444-F490 HydrophobicContact CG2-CE1 3.77Å; I444-F492 HydrophobicContact CG2-CE1 3.91Å; I444-F492 HydrophobicContact CG2-CZ 3.79Å
445Q92.1Very high86.6Confident22 Ų2219.1 Ų19.110%0.10310%0.095CC..Hα-helixtrans-61.5-43.6175.1-176.2179.910.300111.4L326 S441 A442 V443 F447 Y448 M449 H489L326-Q445 HydrophobicContact CD2-CB 4.11Å; L326-Q445 HydrophobicContact CD2-CG 3.92Å; S441-Q445 WeakPolarHBondContact O-CB 3.25Å; S441-Q445 PolarHBondContact O-N 3.18Å; A442-Q445 PolarHBondContact O-N 2.71Å; V443-Q445 VanDerWaalsContact C-N 3.33Å; V443-Q445 PolarHBondContact O-N 2.9Å; Q445-F447 VanDerWaalsContact C-N 3.3Å; Q445-F447 PolarHBondContact O-N 2.77Å; Q445-Y448 WeakPolarHBondContact O-CB 3.48Å; Q445-Y448 PolarHBondContact O-N 3.34Å; Q445-M449 HydrophobicContact CG-SD 4.27Å; Q445-M449 VanDerWaalsContact O-CG 3.27Å; Q445-M449 WeakPolarHBondContact O-CG 3.29Å; Q445-M449 PolarHBondContact O-N 3.32Å; Q445-H489 PolarHBondContact OE1-ND1 2.99Å
446A92.2Very high86.9Confident0 Ų017 Ų170%09%0.089CC..Hα-helixtrans-61.1-37.7173.500000112.6L325 L326 V329 W369 A442 V443 I444 S450L325-A446 HydrophobicContact CD1-CB 4.5Å; L325-A446 HydrophobicContact CD2-CB 4.08Å; L325-A446 HydrophobicContact CG-CB 4.14Å; L326-A446 HydrophobicContact CD2-CB 4.33Å; V329-A446 HydrophobicContact CG1-CB 4.45Å; V329-A446 HydrophobicContact CG2-CB 4.04Å; W369-A446 HydrophobicContact CH2-CB 4.06Å; W369-A446 HydrophobicContact CZ3-CB 4.4Å; A442-A446 PolarHBondContact O-N 3.47Å; V443-A446 WeakPolarHBondContact O-CB 3.44Å; V443-A446 PolarHBondContact O-N 3.02Å; I444-A446 PolarHBondContact O-N 3.33Å; A446-S450 WeakPolarHBondContact O-CB 3.42Å; A446-S450 PolarHBondContact O-N 2.72Å; A446-S450 VanDerWaalsContact O-N 3.1Å; A446-S450 PolarHBondContact O-OG 3.22Å
447F92.9Very high86.4Confident6 Ų625.3 Ų25.33%0.02613%0.127CC..Hα-helixtrans-64.9-47.6174.9-177.8-133.4000111.4W369 V443 I444 Q445 M449 S450 C451 F464 F467W369-F447 HydrophobicContact CB-CD2 4.29Å; W369-F447 HydrophobicContact CB-CE2 4.22Å; W369-F447 AromaticContact CD1-CD2 3.76Å; W369-F447 AromaticContact CD1-CE2 3.71Å; W369-F447 HydrophobicContact CD2-CB 4.17Å; W369-F447 AromaticContact CD2-CD2 3.39Å; W369-F447 HydrophobicContact CD2-CD2 3.39Å; W369-F447 HydrophobicContact CD2-CE2 4.09Å; W369-F447 HydrophobicContact CD2-CG 4.06Å; W369-F447 AromaticContact CE2-CD2 3.56Å; W369-F447 HydrophobicContact CE3-CB 3.7Å; W369-F447 AromaticContact CE3-CD2 3.84Å; W369-F447 HydrophobicContact CE3-CD2 3.84Å; W369-F447 HydrophobicContact CE3-CG 4.02Å; W369-F447 AromaticContact CG-CD2 3.57Å; W369-F447 HydrophobicContact CG-CD2 3.57Å; W369-F447 AromaticContact CG-CE2 3.75Å; W369-F447 HydrophobicContact CG-CE2 3.75Å; W369-F447 HydrophobicContact CG-CG 4.45Å; W369-F447 HydrophobicContact CH2-CB 4.06Å; W369-F447 HydrophobicContact CZ2-CB 4.47Å; W369-F447 HydrophobicContact CZ2-CD2 4.16Å; W369-F447 HydrophobicContact CZ3-CB 3.64Å; W369-F447 HydrophobicContact CZ3-CD2 4.4Å; W369-F447 HydrophobicContact CZ3-CG 4.42Å; W369-F447 AromaticContact NE1-CD2 3.75Å; V443-F447 PolarHBondContact O-N 2.77Å; I444-F447 WeakPolarHBondContact O-CB 3.4Å; I444-F447 PolarHBondContact O-N 3.4Å; Q445-F447 VanDerWaalsContact C-N 3.3Å; Q445-F447 PolarHBondContact O-N 2.77Å; F447-M449 PolarHBondContact O-N 3.07Å; F447-S450 PolarHBondContact O-N 3.39Å; F447-C451 WeakPolarHBondContact CE2-SG 3.17Å; F447-C451 PolarHBondContact O-N 3.48Å; F447-F464 AromaticContact CD1-CD2 3.54Å; F447-F464 HydrophobicContact CD1-CD2 3.54Å; F447-F464 AromaticContact CD1-CE2 3.69Å; F447-F464 HydrophobicContact CD1-CE2 3.69Å; F447-F464 AromaticContact CE1-CD2 3.71Å; F447-F464 HydrophobicContact CE1-CD2 3.71Å; F447-F464 HydrophobicContact CE1-CE2 4.26Å; F447-F464 HydrophobicContact CG-CD2 4.31Å; F447-F464 HydrophobicContact CG-CE2 4.42Å; F447-F467 AromaticContact CD1-CD1 3.99Å; F447-F467 HydrophobicContact CD1-CD1 3.99Å; F447-F467 HydrophobicContact CD1-CD2 4.45Å; F447-F467 HydrophobicContact CD1-CE1 4.1Å; F447-F467 HydrophobicContact CD1-CG 4.17Å; F447-F467 HydrophobicContact CD1-CZ 4.36Å; F447-F467 HydrophobicContact CE1-CB 3.89Å; F447-F467 AromaticContact CE1-CD1 3.88Å; F447-F467 HydrophobicContact CE1-CD1 3.88Å; F447-F467 AromaticContact CE1-CD2 3.92Å; F447-F467 HydrophobicContact CE1-CD2 3.92Å; F447-F467 HydrophobicContact CE1-CE1 4.38Å; F447-F467 HydrophobicContact CE1-CE2 4.4Å; F447-F467 AromaticContact CE1-CG 3.62Å; F447-F467 HydrophobicContact CE1-CG 3.62Å
448Y90.3Very high85.5Confident21 Ų2129.5 Ų29.58%0.08217%0.17CC..Hα-helixtrans-52.4-53.1174.2172.3-115.3000111.4I444 Q445 S450 C451 S452 T460 F464 H491 F492 E495I444-Y448 PolarHBondContact O-N 3.16Å; Q445-Y448 WeakPolarHBondContact O-CB 3.48Å; Q445-Y448 PolarHBondContact O-N 3.34Å; Y448-S450 VanDerWaalsContact C-N 3.28Å; Y448-S450 PolarHBondContact O-N 3.18Å; Y448-C451 PolarHBondContact O-N 2.88Å; Y448-C451 VanDerWaalsContact O-N 3.15Å; Y448-S452 WeakPolarHBondContact CD2-OG 3.35Å; Y448-S452 WeakPolarHBondContact CE2-OG 3.21Å; Y448-S452 WeakPolarHBondContact O-CB 3.43Å; Y448-S452 PolarHBondContact O-N 3.24Å; Y448-S452 PolarHBondContact O-OG 3.08Å; Y448-S452 VanDerWaalsContact O-OG 3.07Å; Y448-T460 HydrophobicContact CE2-CG2 4.45Å; Y448-F464 AromaticContact CD2-CD1 3.71Å; Y448-F464 HydrophobicContact CD2-CD1 3.71Å; Y448-F464 AromaticContact CD2-CE1 3.57Å; Y448-F464 HydrophobicContact CD2-CE1 3.57Å; Y448-F464 HydrophobicContact CD2-CE2 4.43Å; Y448-F464 HydrophobicContact CD2-CG 4.2Å; Y448-F464 AromaticContact CD2-CZ 3.97Å; Y448-F464 HydrophobicContact CD2-CZ 3.97Å; Y448-F464 HydrophobicContact CE2-CD1 4.44Å; Y448-F464 HydrophobicContact CE2-CE1 4.43Å; Y448-F464 HydrophobicContact CG-CE1 4.21Å; Y448-F464 HydrophobicContact CG-CZ 4.17Å; Y448-H491 AromaticContact CD1-NE2 3.99Å; Y448-H491 AromaticContact CE1-NE2 3.63Å; Y448-F492 HydrophobicContact CD1-CB 3.72Å; Y448-F492 HydrophobicContact CD1-CD1 4.1Å; Y448-F492 HydrophobicContact CD1-CG 4.31Å; Y448-F492 HydrophobicContact CD2-CB 3.64Å; Y448-F492 HydrophobicContact CD2-CD1 4.41Å; Y448-F492 HydrophobicContact CD2-CG 4.09Å; Y448-F492 HydrophobicContact CE1-CB 3.54Å; Y448-F492 HydrophobicContact CE2-CB 3.47Å; Y448-F492 VanDerWaalsContact CE2-CB 3.47Å; Y448-F492 HydrophobicContact CE2-CG 4.39Å; Y448-F492 HydrophobicContact CG-CB 3.75Å; Y448-F492 AromaticContact CG-CD1 3.92Å; Y448-F492 HydrophobicContact CG-CD1 3.92Å; Y448-F492 HydrophobicContact CG-CG 4.04Å; Y448-F492 VanDerWaalsContact CZ-CB 3.41Å; Y448-E495 PolarHBondContact OH-OE2 3.1Å
449M88.3Confident85.1Confident31 Ų3132.8 Ų32.815%0.15319%0.185CC..Hα-helixtrans-59-40.2-179.5-66.8164.763.500112.5L326 V329 R330 C333 Q445 F447 S452 C453L326-M449 HydrophobicContact CD2-SD 4.23Å; V329-M449 HydrophobicContact CB-CE 4.32Å; V329-M449 HydrophobicContact CG1-CB 3.9Å; V329-M449 HydrophobicContact CG1-CE 3.95Å; V329-M449 HydrophobicContact CG1-SD 4.35Å; R330-M449 HydrophobicContact CB-CE 4.07Å; R330-M449 HydrophobicContact CG-CE 3.23Å; C333-M449 PolarHBondContact SG-O 3.43Å; Q445-M449 HydrophobicContact CG-SD 4.27Å; Q445-M449 VanDerWaalsContact O-CG 3.27Å; Q445-M449 WeakPolarHBondContact O-CG 3.29Å; Q445-M449 PolarHBondContact O-N 3.32Å; F447-M449 PolarHBondContact O-N 3.07Å; M449-S452 PolarHBondContact O-N 3.47Å; M449-C453 WeakPolarHBondContact O-CB 3.37Å; M449-C453 PolarHBondContact O-N 2.77Å
450S88.4Confident84.6Confident1 Ų132.9 Ų32.91%0.00719%0.189CC..Hα-helixtrans-68.5-33.2179.1-59.20000112.8W369 A446 F447 Y448 C453 Q454W369-S450 WeakPolarHBondContact CZ2-OG 3.43Å; A446-S450 WeakPolarHBondContact O-CB 3.42Å; A446-S450 PolarHBondContact O-N 2.72Å; A446-S450 VanDerWaalsContact O-N 3.1Å; A446-S450 PolarHBondContact O-OG 3.22Å; F447-S450 PolarHBondContact O-N 3.39Å; Y448-S450 VanDerWaalsContact C-N 3.28Å; Y448-S450 PolarHBondContact O-N 3.18Å; S450-C453 PolarHBondContact O-SG 2.86Å; S450-Q454 PolarHBondContact O-NE2 2.95Å
451C86.7Confident84.3Confident4 Ų433.1 Ų33.13%0.02719%0.191CC..Hα-helixtrans-74.5-45.4172.2-73.30000111.5F447 Y448 C453 Q454 F464F447-C451 WeakPolarHBondContact CE2-SG 3.17Å; F447-C451 PolarHBondContact O-N 3.48Å; Y448-C451 PolarHBondContact O-N 2.88Å; Y448-C451 VanDerWaalsContact O-N 3.15Å; C451-C453 VanDerWaalsContact C-N 3.29Å; C451-C453 PolarHBondContact O-N 3.08Å; C451-Q454 WeakPolarHBondContact O-CB 3.44Å; C451-Q454 PolarHBondContact O-N 3.3Å; C451-Q454 VanDerWaalsContact O-N 3.1Å; C451-F464 HydrophobicContact CB-CB 4.14Å
452S84.8Confident83.9Confident19 Ų1936.1 Ų36.113%0.13321%0.21CC..Hα-helixtrans-67.7-25.1-177.8-62.80000113.3Y448 M449 Q454 M455Y448-S452 WeakPolarHBondContact CD2-OG 3.35Å; Y448-S452 WeakPolarHBondContact CE2-OG 3.21Å; Y448-S452 WeakPolarHBondContact O-CB 3.43Å; Y448-S452 PolarHBondContact O-N 3.24Å; Y448-S452 PolarHBondContact O-OG 3.08Å; Y448-S452 VanDerWaalsContact O-OG 3.07Å; M449-S452 PolarHBondContact O-N 3.47Å; S452-Q454 PolarHBondContact O-N 3.05Å; S452-M455 PolarHBondContact O-N 3.5Å
453C84.8Confident83.8Confident7 Ų740.2 Ų40.25%0.04723%0.226CC..THydrogen-bonded Turntrans-72.6-15.2173.877.60000113.8C333 M449 S450 C451C333-C453 HydrophobicContact CB-CB 3.68Å; C333-C453 VanDerWaalsContact SG-SG 3.64Å; M449-C453 WeakPolarHBondContact O-CB 3.37Å; M449-C453 PolarHBondContact O-N 2.77Å; S450-C453 PolarHBondContact O-SG 2.86Å; C451-C453 VanDerWaalsContact C-N 3.29Å; C451-C453 PolarHBondContact O-N 3.08Å
454Q82.8Confident83.6Confident85 Ų8540.2 Ų40.240%0.39723%0.226SC..THydrogen-bonded Turntrans-91.6-9.4174.8-58.2173.844.300112.6F336 F362 S450 C451 S452F336-Q454 HydrophobicContact CE1-CG 4.15Å; F336-Q454 HydrophobicContact CZ-CG 4.46Å; F362-Q454 HydrophobicContact CE1-CG 4.26Å; F362-Q454 HydrophobicContact CE2-CG 4.04Å; F362-Q454 HydrophobicContact CZ-CG 3.64Å; F362-Q454 VanDerWaalsContact CZ-NE2 3.34Å; S450-Q454 PolarHBondContact O-NE2 2.95Å; C451-Q454 WeakPolarHBondContact O-CB 3.44Å; C451-Q454 PolarHBondContact O-N 3.3Å; C451-Q454 VanDerWaalsContact O-N 3.1Å; S452-Q454 PolarHBondContact O-N 3.05Å
455M79.5Confident83.2Confident25 Ų2541.8 Ų41.812%0.12323%0.234CC..SBendtrans-102.1155.5-179.6-61-58.6-66.400111.4M349 S452 M459M349-M455 HydrophobicContact CE-CE 4.3Å; M349-M455 HydrophobicContact CE-SD 4.43Å; S452-M455 PolarHBondContact O-N 3.5Å; M455-M459 HydrophobicContact CB-CB 4.39Å; M455-M459 WeakPolarHBondContact CB-O 3.42Å; M455-M459 HydrophobicContact CE-CB 4.18Å
456P72.6Confident83Confident51 Ų5147.6 Ų47.633%0.33126%0.261SS..PPolyproline II helixtrans-56.7154.4165-22.233.9000111.7M349 G458 M459M349-P456 HydrophobicContact CE-CG 4.28Å; P456-G458 PolarHBondContact O-N 3.07Å; P456-M459 HydrophobicContact CB-SD 4.42Å; P456-M459 HydrophobicContact CG-SD 4.21Å; P456-M459 PolarHBondContact O-N 2.79Å
457Q67.3Low83Confident184 Ų18448.5 Ų48.586%0.8627%0.265SS*.THydrogen-bonded Turntrans-56.8132.1178.4-70.5-178.1-11.800111.1M459Q457-M459 VanDerWaalsContact C-N 3.35Å
458G64.9Low82.8Confident90 Ų9048.2 Ų48.293%0.92826%0.264SS*.THydrogen-bonded Turntrans83-0179.400000115.6P456P456-G458 PolarHBondContact O-N 3.07Å
459M73.9Confident82.7Confident114 Ų11449.7 Ų49.756%0.56228%0.277SS*.  trans-104.2124174.3-72.5-171.6162.800111.8M455 P456 Q457M455-M459 HydrophobicContact CB-CB 4.39Å; M455-M459 WeakPolarHBondContact CB-O 3.42Å; M455-M459 HydrophobicContact CE-CB 4.18Å; P456-M459 HydrophobicContact CB-SD 4.42Å; P456-M459 HydrophobicContact CG-SD 4.21Å; P456-M459 PolarHBondContact O-N 2.79Å; Q457-M459 VanDerWaalsContact C-N 3.35Å
460T78.6Confident82.8Confident27 Ų2753.3 Ų53.317%0.16629%0.291CS..  trans-75.8139.3170.3-49.70000110Y448 P462 F464 I465 C496Y448-T460 HydrophobicContact CE2-CG2 4.45Å; T460-P462 WeakPolarHBondContact O-CD 3.31Å; T460-F464 HydrophobicContact CG2-CD1 4.36Å; T460-I465 HydrophobicContact CG2-CD1 4.11Å; T460-I465 HydrophobicContact CG2-CG1 3.76Å; T460-C496 PolarHBondContact OG1-SG 3.34Å
461S83.4Confident82.9Confident8 Ų853.3 Ų53.36%0.05629%0.291CS..  trans-68.4127.4179.1-179.10000111.6R463 F464 I465S461-R463 PolarHBondContact O-N 3.2Å; S461-R463 PolarHBondContact OG-N 3.13Å; S461-F464 WeakPolarHBondContact O-CB 3.36Å; S461-F464 PolarHBondContact O-N 2.61Å; S461-I465 PolarHBondContact O-N 3.21Å
462P83.6Confident82.9Confident64 Ų6454.5 Ų54.542%0.41630%0.298SS..Hα-helixtrans-52-38.2172.5-27.730.9000113.6Y351 T460 F464 I465 E466Y351-P462 WeakPolarHBondContact OH-CB 3.42Å; Y351-P462 WeakPolarHBondContact OH-CD 3.39Å; Y351-P462 VanDerWaalsContact OH-CG 3.27Å; Y351-P462 WeakPolarHBondContact OH-CG 3.47Å; T460-P462 WeakPolarHBondContact O-CD 3.31Å; P462-F464 VanDerWaalsContact C-N 3.3Å; P462-F464 PolarHBondContact O-N 2.78Å; P462-I465 PolarHBondContact O-N 2.69Å; P462-E466 PolarHBondContact O-N 3.15Å
463R86.3Confident82.9Confident85 Ų8558.6 Ų58.632%0.32132%0.315SS..Hα-helixtrans-59.9-39.7175.2179.9-178.3172.8-176.2-1.8112.4E366 S461 F467E366-R463 IonicContact OE1-CZ 3.97Å; E366-R463 IonicContact OE1-NH1 3.1Å; E366-R463 PolarHBondContact OE1-NH1 3.44Å; E366-R463 IonicContact OE1-NH2 3.16Å; E366-R463 PolarHBondContact OE1-NH2 3.34Å; E366-R463 IonicContact OE2-CZ 3.04Å; E366-R463 IonicContact OE2-NH1 3.87Å; E366-R463 IonicContact OE2-NH2 3.93Å; E366-R463 PolarHBondContact OE2-NH2 3.5Å; S461-R463 PolarHBondContact O-N 3.2Å; S461-R463 PolarHBondContact OG-N 3.13Å; R463-F467 PolarHBondContact O-N 3.28Å; R463-F467 VanDerWaalsContact O-N 3.13Å
464F88.4Confident83Confident0 Ų058.3 Ų58.30%031%0.312CS..Hα-helixtrans-74.7-37178.6-173.1-98.7000111.5I444 F447 Y448 C451 T460 S461 P462 F467 V468 F492I444-F464 HydrophobicContact CG2-CE2 4.36Å; I444-F464 HydrophobicContact CG2-CZ 4.24Å; F447-F464 AromaticContact CD1-CD2 3.54Å; F447-F464 HydrophobicContact CD1-CD2 3.54Å; F447-F464 AromaticContact CD1-CE2 3.69Å; F447-F464 HydrophobicContact CD1-CE2 3.69Å; F447-F464 AromaticContact CE1-CD2 3.71Å; F447-F464 HydrophobicContact CE1-CD2 3.71Å; F447-F464 HydrophobicContact CE1-CE2 4.26Å; F447-F464 HydrophobicContact CG-CD2 4.31Å; F447-F464 HydrophobicContact CG-CE2 4.42Å; Y448-F464 AromaticContact CD2-CD1 3.71Å; Y448-F464 HydrophobicContact CD2-CD1 3.71Å; Y448-F464 AromaticContact CD2-CE1 3.57Å; Y448-F464 HydrophobicContact CD2-CE1 3.57Å; Y448-F464 HydrophobicContact CD2-CE2 4.43Å; Y448-F464 HydrophobicContact CD2-CG 4.2Å; Y448-F464 AromaticContact CD2-CZ 3.97Å; Y448-F464 HydrophobicContact CD2-CZ 3.97Å; Y448-F464 HydrophobicContact CE2-CD1 4.44Å; Y448-F464 HydrophobicContact CE2-CE1 4.43Å; Y448-F464 HydrophobicContact CG-CE1 4.21Å; Y448-F464 HydrophobicContact CG-CZ 4.17Å; C451-F464 HydrophobicContact CB-CB 4.14Å; T460-F464 HydrophobicContact CG2-CD1 4.36Å; S461-F464 WeakPolarHBondContact O-CB 3.36Å; S461-F464 PolarHBondContact O-N 2.61Å; P462-F464 VanDerWaalsContact C-N 3.3Å; P462-F464 PolarHBondContact O-N 2.78Å; F464-F467 HydrophobicContact CD2-CD1 4.43Å; F464-F467 HydrophobicContact CE2-CD1 4.21Å; F464-F467 WeakPolarHBondContact O-CB 3.44Å; F464-F467 PolarHBondContact O-N 3.37Å; F464-V468 HydrophobicContact CD1-CG2 4Å; F464-V468 HydrophobicContact CE1-CG2 3.53Å; F464-V468 HydrophobicContact CZ-CG2 3.81Å; F464-V468 WeakPolarHBondContact O-CG2 3.47Å; F464-V468 PolarHBondContact O-N 3.2Å; F464-F492 HydrophobicContact CE1-CD1 4.35Å; F464-F492 AromaticContact CE1-CD2 3.48Å; F464-F492 HydrophobicContact CE1-CD2 3.48Å; F464-F492 VanDerWaalsContact CE1-CD2 3.48Å; F464-F492 HydrophobicContact CE1-CE1 4.47Å; F464-F492 AromaticContact CE1-CE2 3.64Å; F464-F492 HydrophobicContact CE1-CE2 3.64Å; F464-F492 AromaticContact CE1-CG 3.89Å; F464-F492 HydrophobicContact CE1-CG 3.89Å; F464-F492 HydrophobicContact CE1-CZ 4.16Å; F464-F492 HydrophobicContact CZ-CD1 4.13Å; F464-F492 AromaticContact CZ-CD2 3.9Å; F464-F492 HydrophobicContact CZ-CD2 3.9Å; F464-F492 AromaticContact CZ-CE1 3.92Å; F464-F492 HydrophobicContact CZ-CE1 3.92Å; F464-F492 AromaticContact CZ-CE2 3.69Å; F464-F492 HydrophobicContact CZ-CE2 3.69Å; F464-F492 HydrophobicContact CZ-CG 4.12Å; F464-F492 AromaticContact CZ-CZ 3.72Å; F464-F492 HydrophobicContact CZ-CZ 3.72Å
465I85.9Confident83.3Confident34 Ų3454.2 Ų54.217%0.17429%0.293CS..Hα-helixtrans-60.8-46.5173.2-63.6170.1000110.2T460 S461 P462 F467 V468 C469 L499T460-I465 HydrophobicContact CG2-CD1 4.11Å; T460-I465 HydrophobicContact CG2-CG1 3.76Å; S461-I465 PolarHBondContact O-N 3.21Å; P462-I465 PolarHBondContact O-N 2.69Å; I465-F467 VanDerWaalsContact C-N 3.31Å; I465-F467 PolarHBondContact O-N 2.73Å; I465-V468 PolarHBondContact O-N 2.94Å; I465-C469 WeakPolarHBondContact O-CB 3.2Å; I465-C469 PolarHBondContact O-N 2.8Å; I465-C469 PolarHBondContact O-SG 3.36Å; I465-L499 HydrophobicContact CG2-CD2 4.44Å
466E87.9Confident83.6Confident144 Ų14455 Ų5567%0.67330%0.296SS*.Hα-helixtrans-58.4-42.7175.7-173.1-179.7-177.300111.7P462 C469 K470P462-E466 PolarHBondContact O-N 3.15Å; E466-C469 PolarHBondContact O-N 3.06Å; E466-K470 WeakPolarHBondContact O-CB 3.43Å; E466-K470 PolarHBondContact O-N 3.43Å
467F91.1Very high84.1Confident18 Ų1853.5 Ų53.58%0.07929%0.286CS..Hα-helixtrans-61-47174.9172.1-93.3000112.7L372 L376 I444 F447 R463 F464 I465 C469 K470 H471L372-F467 HydrophobicContact CD2-CE2 4.32Å; L372-F467 HydrophobicContact CD2-CZ 3.74Å; L372-F467 HydrophobicContact CG-CZ 4.15Å; L376-F467 HydrophobicContact CD1-CE1 4.23Å; L376-F467 HydrophobicContact CD1-CE2 3.96Å; L376-F467 HydrophobicContact CD1-CZ 3.38Å; I444-F467 HydrophobicContact CG1-CE1 4.3Å; I444-F467 HydrophobicContact CG1-CZ 4.35Å; I444-F467 HydrophobicContact CG2-CE1 4.26Å; F447-F467 AromaticContact CD1-CD1 3.99Å; F447-F467 HydrophobicContact CD1-CD1 3.99Å; F447-F467 HydrophobicContact CD1-CD2 4.45Å; F447-F467 HydrophobicContact CD1-CE1 4.1Å; F447-F467 HydrophobicContact CD1-CG 4.17Å; F447-F467 HydrophobicContact CD1-CZ 4.36Å; F447-F467 HydrophobicContact CE1-CB 3.89Å; F447-F467 AromaticContact CE1-CD1 3.88Å; F447-F467 HydrophobicContact CE1-CD1 3.88Å; F447-F467 AromaticContact CE1-CD2 3.92Å; F447-F467 HydrophobicContact CE1-CD2 3.92Å; F447-F467 HydrophobicContact CE1-CE1 4.38Å; F447-F467 HydrophobicContact CE1-CE2 4.4Å; F447-F467 AromaticContact CE1-CG 3.62Å; F447-F467 HydrophobicContact CE1-CG 3.62Å; R463-F467 PolarHBondContact O-N 3.28Å; R463-F467 VanDerWaalsContact O-N 3.13Å; F464-F467 HydrophobicContact CD2-CD1 4.43Å; F464-F467 HydrophobicContact CE2-CD1 4.21Å; F464-F467 WeakPolarHBondContact O-CB 3.44Å; F464-F467 PolarHBondContact O-N 3.37Å; I465-F467 VanDerWaalsContact C-N 3.31Å; I465-F467 PolarHBondContact O-N 2.73Å; F467-C469 VanDerWaalsContact C-N 3.32Å; F467-C469 PolarHBondContact O-N 3.45Å; F467-K470 PolarHBondContact O-N 2.8Å; F467-H471 AromaticContact CD2-CD2 3.73Å; F467-H471 AromaticContact CE2-CD2 3.58Å; F467-H471 AromaticContact CE2-NE2 3.88Å; F467-H471 PolarHBondContact O-CD2 3.17Å; F467-H471 PolarHBondContact O-N 2.98Å
468V89.8Confident85Confident0 Ų044.8 Ų44.80%025%0.246CC..Hα-helixtrans-64.4-38.6177.2172.80000111F464 I465 H471 D472 L475 F492 L493 L499 F503F464-V468 HydrophobicContact CD1-CG2 4Å; F464-V468 HydrophobicContact CE1-CG2 3.53Å; F464-V468 HydrophobicContact CZ-CG2 3.81Å; F464-V468 WeakPolarHBondContact O-CG2 3.47Å; F464-V468 PolarHBondContact O-N 3.2Å; I465-V468 PolarHBondContact O-N 2.94Å; V468-H471 PolarHBondContact O-N 3.34Å; V468-D472 WeakPolarHBondContact O-CA 2.97Å; V468-D472 PolarHBondContact O-N 3Å; V468-D472 VanDerWaalsContact O-N 3.11Å; V468-L475 HydrophobicContact CB-CD1 4.25Å; V468-L475 HydrophobicContact CG1-CD1 3.79Å; V468-L475 HydrophobicContact CG2-CD1 4.26Å; V468-F492 HydrophobicContact CG2-CE2 4.07Å; V468-L493 HydrophobicContact CG1-CD2 4.25Å; V468-L499 HydrophobicContact CB-CD1 4.43Å; V468-L499 HydrophobicContact CB-CD2 4.13Å; V468-L499 HydrophobicContact CG1-CD1 4.22Å; V468-L499 HydrophobicContact CG1-CD2 3.66Å; V468-L499 HydrophobicContact CG2-CD1 4.29Å; V468-F503 HydrophobicContact CG1-CE2 4.09Å; V468-F503 HydrophobicContact CG1-CZ 4.45Å
469C87.4Confident85.8Confident53 Ų5340.5 Ų40.536%0.35820%0.202SC..Hα-helixtrans-66.2-37.2176.2-73.30000112.8I465 E466 F467 R502I465-C469 WeakPolarHBondContact O-CB 3.2Å; I465-C469 PolarHBondContact O-N 2.8Å; I465-C469 PolarHBondContact O-SG 3.36Å; E466-C469 PolarHBondContact O-N 3.06Å; F467-C469 VanDerWaalsContact C-N 3.32Å; F467-C469 PolarHBondContact O-N 3.45Å; C469-R502 PolarHBondContact SG-NH1 3.03Å
470K90.4Very high86.1Confident106 Ų10639.4 Ų39.446%0.46120%0.202SC..Hα-helixtrans-66.4-35.5176.9-178.9-176.9172.7-167.70112.8D373 E466 F467D373-K470 IonicContact OD1-NZ 2.77Å; D373-K470 PolarHBondContact OD1-NZ 3.16Å; D373-K470 IonicContact OD2-NZ 2.73Å; D373-K470 PolarHBondContact OD2-NZ 2.89Å; E466-K470 WeakPolarHBondContact O-CB 3.43Å; E466-K470 PolarHBondContact O-N 3.43Å; F467-K470 PolarHBondContact O-N 2.8Å
471H90.4Very high86Confident2 Ų243 Ų431%0.00921%0.212CC..THydrogen-bonded Turntrans-111.324.2-174.2-63.8-67.8000113.4D373 L376 F467 V468 E473 V474 L475D373-H471 IonicContact OD1-CD2 3.43Å; D373-H471 IonicContact OD1-CE1 2.82Å; D373-H471 PolarHBondContact OD1-CE1 3.46Å; D373-H471 IonicContact OD1-NE2 3.96Å; D373-H471 PolarHBondContact OD1-NE2 3.23Å; L376-H471 WeakPolarHBondContact CB-ND1 3.49Å; L376-H471 HydrophobicContact CD1-CB 4.2Å; F467-H471 AromaticContact CD2-CD2 3.73Å; F467-H471 AromaticContact CE2-CD2 3.58Å; F467-H471 AromaticContact CE2-NE2 3.88Å; F467-H471 PolarHBondContact O-CD2 3.17Å; F467-H471 PolarHBondContact O-N 2.98Å; V468-H471 PolarHBondContact O-N 3.34Å; H471-E473 PolarHBondContact O-N 3.4Å; H471-V474 PolarHBondContact O-N 3.22Å; H471-L475 WeakPolarHBondContact O-CG 3.37Å; H471-L475 PolarHBondContact O-N 2.88Å; H471-L475 VanDerWaalsContact O-N 3.09Å
472D87.8Confident85.8Confident29 Ų2944.8 Ų44.816%0.15522%0.221CC..Hα-helixtrans-59.4-44.4-169.562.6-9.2000113.4V468 V474 L475 K476 R502V468-D472 WeakPolarHBondContact O-CA 2.97Å; V468-D472 PolarHBondContact O-N 3Å; V468-D472 VanDerWaalsContact O-N 3.11Å; D472-V474 PolarHBondContact O-N 3.39Å; D472-L475 PolarHBondContact O-N 2.79Å; D472-K476 VanDerWaalsContact O-CG 3.28Å; D472-K476 WeakPolarHBondContact O-CG 3.47Å; D472-K476 PolarHBondContact O-N 3.18Å; D472-R502 IonicContact OD2-CZ 2.73Å; D472-R502 IonicContact OD2-NH1 3.86Å; D472-R502 PolarHBondContact OD2-NH1 2.94Å; D472-R502 IonicContact OD2-NH2 3.5Å; D472-R502 PolarHBondContact OD2-NH2 3.37Å
473E85.1Confident85.3Confident105 Ų10544 Ų4449%0.49122%0.216SC..Hα-helixtrans-63-38.5178.4-66.3-52.3124.100113H471 K476 C477H471-E473 PolarHBondContact O-N 3.4Å; E473-K476 PolarHBondContact O-N 2.85Å; E473-K476 IonicContact OE1-NZ 2.72Å; E473-K476 PolarHBondContact OE1-NZ 3.03Å; E473-C477 WeakPolarHBondContact O-CB 3.05Å; E473-C477 PolarHBondContact O-N 3.05Å
474V86.9Confident84.9Confident0 Ų045.9 Ų45.90%023%0.226CC..Hα-helixtrans-67.5-42.9177.2-179.20000110.6L376 I379 L383 H471 D472 C477 F478L376-V474 HydrophobicContact CD2-CG1 3.83Å; I379-V474 HydrophobicContact CB-CG1 4.24Å; I379-V474 HydrophobicContact CG2-CG1 3.78Å; I379-V474 HydrophobicContact CG2-CG2 4.32Å; L383-V474 HydrophobicContact CD1-CG2 4.23Å; H471-V474 PolarHBondContact O-N 3.22Å; D472-V474 PolarHBondContact O-N 3.39Å; V474-C477 WeakPolarHBondContact O-CB 3.17Å; V474-C477 PolarHBondContact O-N 2.85Å; V474-F478 HydrophobicContact CG1-CD1 4.3Å; V474-F478 HydrophobicContact CG1-CE1 3.74Å; V474-F478 HydrophobicContact CG1-CE2 4.28Å; V474-F478 HydrophobicContact CG1-CZ 3.73Å; V474-F478 WeakPolarHBondContact O-CD1 3.47Å; V474-F478 PolarHBondContact O-N 3.23Å
475L87.8Confident84.6Confident0 Ų045.9 Ų45.90%023%0.227CC..Hα-helixtrans-64.9-42.2177.7-63.7174.5000111.5I444 V468 H471 D472 C477 F478 V479 F490 F503I444-L475 HydrophobicContact CD1-CD2 3.73Å; V468-L475 HydrophobicContact CB-CD1 4.25Å; V468-L475 HydrophobicContact CG1-CD1 3.79Å; V468-L475 HydrophobicContact CG2-CD1 4.26Å; H471-L475 WeakPolarHBondContact O-CG 3.37Å; H471-L475 PolarHBondContact O-N 2.88Å; H471-L475 VanDerWaalsContact O-N 3.09Å; D472-L475 PolarHBondContact O-N 2.79Å; L475-C477 VanDerWaalsContact C-N 3.29Å; L475-C477 PolarHBondContact O-N 3.33Å; L475-F478 PolarHBondContact O-N 3.34Å; L475-V479 WeakPolarHBondContact O-CG2 3.42Å; L475-V479 PolarHBondContact O-N 2.7Å; L475-V479 VanDerWaalsContact O-N 3.08Å; L475-F490 HydrophobicContact CB-CE2 4.44Å; L475-F490 HydrophobicContact CD2-CE1 4.4Å; L475-F490 HydrophobicContact CD2-CE2 3.71Å; L475-F490 HydrophobicContact CD2-CZ 3.51Å; L475-F503 HydrophobicContact CB-CE1 3.94Å; L475-F503 HydrophobicContact CB-CZ 3.89Å; L475-F503 HydrophobicContact CD1-CZ 4.39Å
476K86Confident84.4Confident40 Ų4044.3 Ų44.317%0.17422%0.219CC..Hα-helixtrans-59.2-42.5173.4-71.6176.5-167.1162.90111D472 E473 V479 T480 F503 I506D472-K476 VanDerWaalsContact O-CG 3.28Å; D472-K476 WeakPolarHBondContact O-CG 3.47Å; D472-K476 PolarHBondContact O-N 3.18Å; E473-K476 PolarHBondContact O-N 2.85Å; E473-K476 IonicContact OE1-NZ 2.72Å; E473-K476 PolarHBondContact OE1-NZ 3.03Å; K476-V479 PolarHBondContact O-N 3.33Å; K476-T480 VanDerWaalsContact O-CB 3.32Å; K476-T480 WeakPolarHBondContact O-CB 3.35Å; K476-T480 PolarHBondContact O-N 3.03Å; K476-T480 PolarHBondContact O-OG1 2.9Å; K476-F503 HydrophobicContact CB-CE1 4.35Å; K476-F503 HydrophobicContact CG-CD1 3.95Å; K476-F503 HydrophobicContact CG-CE1 3.52Å; K476-F503 HydrophobicContact CG-CZ 4.22Å; K476-I506 HydrophobicContact CB-CD1 3.51Å; K476-I506 HydrophobicContact CD-CD1 4.29Å; K476-I506 HydrophobicContact CG-CD1 3.55Å
477C83.3Confident83.9Confident20 Ų2039.1 Ų39.114%0.13519%0.194CC..Hα-helixtrans-61.2-45.8176.5-176.30000112.1L383 E473 V474 L475 V479 T480 R481L383-C477 HydrophobicContact CD1-CB 4.08Å; E473-C477 WeakPolarHBondContact O-CB 3.05Å; E473-C477 PolarHBondContact O-N 3.05Å; V474-C477 WeakPolarHBondContact O-CB 3.17Å; V474-C477 PolarHBondContact O-N 2.85Å; L475-C477 VanDerWaalsContact C-N 3.29Å; L475-C477 PolarHBondContact O-N 3.33Å; C477-V479 PolarHBondContact O-N 2.63Å; C477-T480 PolarHBondContact O-N 3.42Å; C477-R481 WeakPolarHBondContact O-CB 3.46Å; C477-R481 VanDerWaalsContact O-CG 3.31Å; C477-R481 WeakPolarHBondContact O-CG 3.42Å; C477-R481 PolarHBondContact O-N 2.88Å; C477-R481 PolarHBondContact SG-NE 3.36Å; C477-R481 VanDerWaalsContact SG-NE 3.41Å
478F85.4Confident83.3Confident1 Ų142.9 Ų42.90%0.00422%0.215CC..Hα-helixtrans-59-48.8177.7-73.82.2000111.9L376 I379 I433 A437 L440 V474 L475 R481 N482 I485 F490L376-F478 HydrophobicContact CD2-CE2 4.07Å; L376-F478 HydrophobicContact CD2-CZ 4.11Å; I379-F478 HydrophobicContact CD1-CE1 4.24Å; I379-F478 HydrophobicContact CD1-CZ 3.91Å; I379-F478 HydrophobicContact CG2-CE1 4.47Å; I433-F478 HydrophobicContact CG2-CD1 4.11Å; I433-F478 HydrophobicContact CG2-CE1 3.9Å; A437-F478 HydrophobicContact CB-CB 4.27Å; A437-F478 HydrophobicContact CB-CD1 3.8Å; A437-F478 HydrophobicContact CB-CD2 4.15Å; A437-F478 HydrophobicContact CB-CE1 4.14Å; A437-F478 HydrophobicContact CB-CE2 4.47Å; A437-F478 HydrophobicContact CB-CG 3.81Å; A437-F478 HydrophobicContact CB-CZ 4.47Å; L440-F478 HydrophobicContact CB-CE2 3.88Å; L440-F478 HydrophobicContact CB-CZ 4.29Å; L440-F478 HydrophobicContact CD1-CE2 4.14Å; L440-F478 HydrophobicContact CD1-CZ 3.67Å; V474-F478 HydrophobicContact CG1-CD1 4.3Å; V474-F478 HydrophobicContact CG1-CE1 3.74Å; V474-F478 HydrophobicContact CG1-CE2 4.28Å; V474-F478 HydrophobicContact CG1-CZ 3.73Å; V474-F478 WeakPolarHBondContact O-CD1 3.47Å; V474-F478 PolarHBondContact O-N 3.23Å; L475-F478 PolarHBondContact O-N 3.34Å; F478-R481 PolarHBondContact O-N 3.45Å; F478-N482 PolarHBondContact O-N 2.99Å; F478-I485 HydrophobicContact CB-CD1 4.24Å; F478-F490 HydrophobicContact CD2-CZ 4.37Å
479V82.8Confident82.9Confident0 Ų043 Ų430%022%0.215CC..Hα-helixtrans-66.5-41.7-179.1175.30000111.7L475 K476 C477 R481 N482 P483 I486 F490 I506L475-V479 WeakPolarHBondContact O-CG2 3.42Å; L475-V479 PolarHBondContact O-N 2.7Å; L475-V479 VanDerWaalsContact O-N 3.08Å; K476-V479 PolarHBondContact O-N 3.33Å; C477-V479 PolarHBondContact O-N 2.63Å; V479-R481 VanDerWaalsContact C-N 3.26Å; V479-R481 PolarHBondContact O-N 2.89Å; V479-N482 CarbonylContact O-C 3.06Å; V479-N482 PolarHBondContact O-N 2.91Å; V479-P483 VanDerWaalsContact O-N 3.13Å; V479-I486 HydrophobicContact CB-CD1 4.42Å; V479-I486 HydrophobicContact CB-CG1 4.32Å; V479-I486 HydrophobicContact CG1-CD1 3.16Å; V479-I486 HydrophobicContact CG1-CG1 3.43Å; V479-I486 VanDerWaalsContact CG1-CG1 3.43Å; V479-I486 HydrophobicContact CG2-CD1 4.43Å; V479-I486 HydrophobicContact CG2-CG1 3.84Å; V479-F490 HydrophobicContact CG2-CD2 3.75Å; V479-F490 HydrophobicContact CG2-CE2 4.05Å; V479-I506 HydrophobicContact CB-CG2 4.09Å; V479-I506 HydrophobicContact CG1-CB 4.41Å; V479-I506 HydrophobicContact CG1-CG2 3.34Å
480T79.3Confident82.8Confident92 Ų9240.5 Ų40.556%0.56420%0.198SC*.Hα-helixtrans-63.3-36.8-179.8-570000111.3K476 C477K476-T480 VanDerWaalsContact O-CB 3.32Å; K476-T480 WeakPolarHBondContact O-CB 3.35Å; K476-T480 PolarHBondContact O-N 3.03Å; K476-T480 PolarHBondContact O-OG1 2.9Å; C477-T480 PolarHBondContact O-N 3.42Å
481R77.3Confident82.2Confident102 Ų10237.1 Ų37.139%0.38518%0.184SC..Hα-helixtrans-81.4-33.5-180-70173.7170.2-146.8-4.5113.3D431 C477 F478 V479D431-R481 IonicContact OD1-NH1 3.4Å; D431-R481 PolarHBondContact OD1-NH1 3.48Å; D431-R481 IonicContact OD2-CZ 3.43Å; D431-R481 IonicContact OD2-NH1 2.77Å; D431-R481 PolarHBondContact OD2-NH1 3.39Å; D431-R481 IonicContact OD2-NH2 3.46Å; D431-R481 PolarHBondContact OD2-NH2 2.97Å; C477-R481 WeakPolarHBondContact O-CB 3.46Å; C477-R481 VanDerWaalsContact O-CG 3.31Å; C477-R481 WeakPolarHBondContact O-CG 3.42Å; C477-R481 PolarHBondContact O-N 2.88Å; C477-R481 PolarHBondContact SG-NE 3.36Å; C477-R481 VanDerWaalsContact SG-NE 3.41Å; F478-R481 PolarHBondContact O-N 3.45Å; V479-R481 VanDerWaalsContact C-N 3.26Å; V479-R481 PolarHBondContact O-N 2.89Å
482N78.5Confident81.7Confident46 Ų4637.1 Ų37.125%0.24618%0.184CC..  trans-132.289.8173.7-174.93.3000110.8N438 F478 V479 K484 I485N438-N482 PolarHBondContact OD1-ND2 3.47Å; F478-N482 PolarHBondContact O-N 2.99Å; V479-N482 CarbonylContact O-C 3.06Å; V479-N482 PolarHBondContact O-N 2.91Å; N482-K484 PolarHBondContact O-N 3.47Å; N482-K484 PolarHBondContact OD1-N 2.95Å; N482-I485 HydrophobicContact CB-CD1 3.73Å; N482-I485 HydrophobicContact CB-CG1 3.92Å; N482-I485 WeakPolarHBondContact O-CB 3.34Å; N482-I485 WeakPolarHBondContact O-CG1 3.42Å; N482-I485 PolarHBondContact O-N 3.49Å
483P74.3Confident81.4Confident47 Ų4735.8 Ų35.831%0.30518%0.177SC..THydrogen-bonded Turntrans-37.9-43.2172.5-44.345.2000116.3V479 I485 I486 Q510V479-P483 VanDerWaalsContact O-N 3.13Å; P483-I485 PolarHBondContact O-N 3.35Å; P483-I485 VanDerWaalsContact O-N 3.13Å; P483-I486 PolarHBondContact O-N 3.23Å; P483-Q510 VanDerWaalsContact C-OE1 3.28Å; P483-Q510 PolarHBondContact O-OE1 3.12Å; P483-Q510 VanDerWaalsContact O-OE1 3.09Å
484K76.6Confident80.9Confident124 Ų12431 Ų3154%0.53916%0.155SC..THydrogen-bonded Turntrans-68.7-15.5-173.3-61.9-174176.4-174.90113.9N482 I486 F487 N488N482-K484 PolarHBondContact O-N 3.47Å; N482-K484 PolarHBondContact OD1-N 2.95Å; K484-I486 VanDerWaalsContact C-N 3.28Å; K484-I486 PolarHBondContact O-N 2.81Å; K484-F487 PolarHBondContact O-N 3.06Å; K484-N488 WeakPolarHBondContact O-CB 3.21Å; K484-N488 VanDerWaalsContact O-CG 3.27Å; K484-N488 PolarHBondContact O-N 2.6Å; K484-N488 PolarHBondContact O-ND2 3.13Å
485I82.3Confident80.2Confident1 Ų135.4 Ų35.41%0.00518%0.175CC..Hα-helixtrans-62.8-34.9179.8-69.3179.2000111.7A437 N438 S441 F478 N482 P483 F487 H489 F490A437-I485 HydrophobicContact CB-CD1 3.89Å; N438-I485 WeakPolarHBondContact OD1-CG1 3.27Å; S441-I485 WeakPolarHBondContact OG-CG2 3.4Å; F478-I485 HydrophobicContact CB-CD1 4.24Å; N482-I485 HydrophobicContact CB-CD1 3.73Å; N482-I485 HydrophobicContact CB-CG1 3.92Å; N482-I485 WeakPolarHBondContact O-CB 3.34Å; N482-I485 WeakPolarHBondContact O-CG1 3.42Å; N482-I485 PolarHBondContact O-N 3.49Å; P483-I485 PolarHBondContact O-N 3.35Å; P483-I485 VanDerWaalsContact O-N 3.13Å; I485-F487 VanDerWaalsContact C-N 3.31Å; I485-F487 PolarHBondContact O-N 3.34Å; I485-H489 HydrophobicContact CG2-CB 4.36Å; I485-H489 PolarHBondContact O-N 3.45Å; I485-F490 HydrophobicContact CG2-CD1 4.29Å; I485-F490 HydrophobicContact CG2-CD2 3.69Å; I485-F490 HydrophobicContact CG2-CE1 4.29Å; I485-F490 HydrophobicContact CG2-CE2 3.67Å; I485-F490 HydrophobicContact CG2-CG 4Å; I485-F490 HydrophobicContact CG2-CZ 3.98Å; I485-F490 PolarHBondContact O-N 3.23Å
486I81.8Confident79.7Confident1 Ų135.7 Ų35.71%0.00518%0.177CC..Hα-helixtrans-54-51.8176.4-81.1166.6000110.2V479 P483 K484 F490 H491 L494 I507 Q510V479-I486 HydrophobicContact CB-CD1 4.42Å; V479-I486 HydrophobicContact CB-CG1 4.32Å; V479-I486 HydrophobicContact CG1-CD1 3.16Å; V479-I486 HydrophobicContact CG1-CG1 3.43Å; V479-I486 VanDerWaalsContact CG1-CG1 3.43Å; V479-I486 HydrophobicContact CG2-CD1 4.43Å; V479-I486 HydrophobicContact CG2-CG1 3.84Å; P483-I486 PolarHBondContact O-N 3.23Å; K484-I486 VanDerWaalsContact C-N 3.28Å; K484-I486 PolarHBondContact O-N 2.81Å; I486-F490 CarbonylContact O-C 3.12Å; I486-F490 WeakPolarHBondContact O-CA 3.1Å; I486-F490 PolarHBondContact O-N 2.88Å; I486-H491 PolarHBondContact O-N 3.45Å; I486-L494 HydrophobicContact CG2-CD1 3.6Å; I486-L494 HydrophobicContact CG2-CD2 4.15Å; I486-L494 HydrophobicContact CG2-CG 4.04Å; I486-I507 HydrophobicContact CD1-CG1 3.81Å; I486-Q510 HydrophobicContact CD1-CG 3.87Å
487F78.4Confident79.1Confident34 Ų3437.9 Ų37.915%0.14920%0.196CC..Hα-helixtrans-78.2-37.2-173-53-61.9000112K484 I485 L494 Q510 D514 R515 W518K484-F487 PolarHBondContact O-N 3.06Å; I485-F487 VanDerWaalsContact C-N 3.31Å; I485-F487 PolarHBondContact O-N 3.34Å; F487-L494 HydrophobicContact CD1-CD1 4.26Å; F487-L494 HydrophobicContact CE1-CD1 4.25Å; F487-Q510 HydrophobicContact CE2-CB 4.22Å; F487-Q510 HydrophobicContact CE2-CG 4.43Å; F487-Q510 HydrophobicContact CZ-CB 4.17Å; F487-Q510 HydrophobicContact CZ-CG 4.39Å; F487-D514 HydrophobicContact CD2-CB 4.14Å; F487-D514 HydrophobicContact CE2-CB 3.7Å; F487-D514 HydrophobicContact CZ-CB 4.29Å; F487-R515 HydrophobicContact CE1-CG 4.15Å; F487-R515 HydrophobicContact CZ-CB 4.45Å; F487-R515 HydrophobicContact CZ-CG 3.6Å; F487-W518 HydrophobicContact CD1-CB 3.53Å; F487-W518 AromaticContact CD1-CD1 3.43Å; F487-W518 VanDerWaalsContact CD1-CD1 3.43Å; F487-W518 HydrophobicContact CD1-CD2 4.29Å; F487-W518 AromaticContact CD1-CG 3.44Å; F487-W518 HydrophobicContact CD1-CG 3.44Å; F487-W518 VanDerWaalsContact CD1-CG 3.44Å; F487-W518 HydrophobicContact CE1-CB 3.75Å; F487-W518 AromaticContact CE1-CG 3.89Å; F487-W518 HydrophobicContact CE1-CG 3.89Å; F487-W518 HydrophobicContact CG-CB 4.45Å
488N78.8Confident78.8Confident97 Ų9743 Ų4352%0.51922%0.217SC..Hα-helixtrans-77.5-39.9-176.5-67.7-12.8000113.7K484K484-N488 WeakPolarHBondContact O-CB 3.21Å; K484-N488 VanDerWaalsContact O-CG 3.27Å; K484-N488 PolarHBondContact O-N 2.6Å; K484-N488 PolarHBondContact O-ND2 3.13Å
489H81.4Confident78.6Confident4 Ų443 Ų432%0.01922%0.217CC..THydrogen-bonded Turntrans-125.2-40.7-169.4-63.5-54.3000113Y318 M322 Q445 I485 H491Y318-H489 PolarHBondContact OH-NE2 3.35Å; M322-H489 VanDerWaalsContact SD-CE1 3.59Å; Q445-H489 PolarHBondContact OE1-ND1 2.99Å; I485-H489 HydrophobicContact CG2-CB 4.36Å; I485-H489 PolarHBondContact O-N 3.45Å; H489-H491 PolarHBondContact O-ND1 3.41Å
490F84.9Confident78.5Confident0 Ų043.3 Ų43.30%022%0.219CC..  trans-99.932.1-172.4-59.6-13.5000114.5S441 I444 L475 F478 V479 I485 I486 F492 L493S441-F490 WeakPolarHBondContact OG-CZ 3.36Å; I444-F490 HydrophobicContact CB-CE1 3.98Å; I444-F490 HydrophobicContact CD1-CE1 3.99Å; I444-F490 HydrophobicContact CD1-CZ 3.87Å; I444-F490 HydrophobicContact CG2-CD1 4.38Å; I444-F490 HydrophobicContact CG2-CE1 3.77Å; L475-F490 HydrophobicContact CB-CE2 4.44Å; L475-F490 HydrophobicContact CD2-CE1 4.4Å; L475-F490 HydrophobicContact CD2-CE2 3.71Å; L475-F490 HydrophobicContact CD2-CZ 3.51Å; F478-F490 HydrophobicContact CD2-CZ 4.37Å; V479-F490 HydrophobicContact CG2-CD2 3.75Å; V479-F490 HydrophobicContact CG2-CE2 4.05Å; I485-F490 HydrophobicContact CG2-CD1 4.29Å; I485-F490 HydrophobicContact CG2-CD2 3.69Å; I485-F490 HydrophobicContact CG2-CE1 4.29Å; I485-F490 HydrophobicContact CG2-CE2 3.67Å; I485-F490 HydrophobicContact CG2-CG 4Å; I485-F490 HydrophobicContact CG2-CZ 3.98Å; I485-F490 PolarHBondContact O-N 3.23Å; I486-F490 CarbonylContact O-C 3.12Å; I486-F490 WeakPolarHBondContact O-CA 3.1Å; I486-F490 PolarHBondContact O-N 2.88Å; F490-F492 HydrophobicContact CB-CE1 3.97Å; F490-F492 HydrophobicContact CB-CE2 4.46Å; F490-F492 HydrophobicContact CB-CZ 3.92Å; F490-F492 AromaticContact CD1-CE1 3.38Å; F490-F492 HydrophobicContact CD1-CE1 3.38Å; F490-F492 AromaticContact CD1-CZ 3.42Å; F490-F492 HydrophobicContact CD1-CZ 3.42Å; F490-F492 VanDerWaalsContact CD1-CZ 3.42Å; F490-F492 HydrophobicContact CE1-CE1 4.16Å; F490-F492 HydrophobicContact CE1-CZ 4.02Å; F490-F492 AromaticContact CG-CE1 3.95Å; F490-F492 HydrophobicContact CG-CE1 3.95Å; F490-F492 AromaticContact CG-CZ 3.73Å; F490-F492 HydrophobicContact CG-CZ 3.73Å; F490-F492 PolarHBondContact O-N 3.07Å; F490-L493 HydrophobicContact CB-CD1 3.72Å; F490-L493 HydrophobicContact CB-CG 3.98Å; F490-L493 HydrophobicContact CD2-CD1 3.91Å; F490-L493 HydrophobicContact CG-CD1 4.2Å; F490-L493 WeakPolarHBondContact O-CB 3.34Å; F490-L493 PolarHBondContact O-N 2.94Å
491H77.7Confident78.4Confident35 Ų3542.8 Ų42.816%0.16222%0.219CC..Hα-helixtrans-50-31.2171.264.4-71.2000112.6Y448 I486 H489 L493 L494 E495Y448-H491 AromaticContact CD1-NE2 3.99Å; Y448-H491 AromaticContact CE1-NE2 3.63Å; I486-H491 PolarHBondContact O-N 3.45Å; H489-H491 PolarHBondContact O-ND1 3.41Å; H491-L493 PolarHBondContact O-N 3.33Å; H491-L493 VanDerWaalsContact O-N 3.17Å; H491-L494 WeakPolarHBondContact O-CA 3.43Å; H491-L494 WeakPolarHBondContact O-CB 3.45Å; H491-L494 PolarHBondContact O-N 3.11Å; H491-E495 IonicContact CD2-OE1 3.36Å; H491-E495 PolarHBondContact CD2-OE1 3.43Å; H491-E495 IonicContact CD2-OE2 3.49Å; H491-E495 PolarHBondContact O-N 3.44Å; H491-E495 VanDerWaalsContact O-N 3.09Å
492F80.3Confident78.6Confident2 Ų242.4 Ų42.41%0.00922%0.218CC..Hα-helixtrans-57.6-27.2174.663.5-104.8000114.7I444 Y448 F464 V468 F490 L494 C496 L499I444-F492 HydrophobicContact CG2-CE1 3.91Å; I444-F492 HydrophobicContact CG2-CZ 3.79Å; Y448-F492 HydrophobicContact CD1-CB 3.72Å; Y448-F492 HydrophobicContact CD1-CD1 4.1Å; Y448-F492 HydrophobicContact CD1-CG 4.31Å; Y448-F492 HydrophobicContact CD2-CB 3.64Å; Y448-F492 HydrophobicContact CD2-CD1 4.41Å; Y448-F492 HydrophobicContact CD2-CG 4.09Å; Y448-F492 HydrophobicContact CE1-CB 3.54Å; Y448-F492 HydrophobicContact CE2-CB 3.47Å; Y448-F492 VanDerWaalsContact CE2-CB 3.47Å; Y448-F492 HydrophobicContact CE2-CG 4.39Å; Y448-F492 HydrophobicContact CG-CB 3.75Å; Y448-F492 AromaticContact CG-CD1 3.92Å; Y448-F492 HydrophobicContact CG-CD1 3.92Å; Y448-F492 HydrophobicContact CG-CG 4.04Å; Y448-F492 VanDerWaalsContact CZ-CB 3.41Å; F464-F492 HydrophobicContact CE1-CD1 4.35Å; F464-F492 AromaticContact CE1-CD2 3.48Å; F464-F492 HydrophobicContact CE1-CD2 3.48Å; F464-F492 VanDerWaalsContact CE1-CD2 3.48Å; F464-F492 HydrophobicContact CE1-CE1 4.47Å; F464-F492 AromaticContact CE1-CE2 3.64Å; F464-F492 HydrophobicContact CE1-CE2 3.64Å; F464-F492 AromaticContact CE1-CG 3.89Å; F464-F492 HydrophobicContact CE1-CG 3.89Å; F464-F492 HydrophobicContact CE1-CZ 4.16Å; F464-F492 HydrophobicContact CZ-CD1 4.13Å; F464-F492 AromaticContact CZ-CD2 3.9Å; F464-F492 HydrophobicContact CZ-CD2 3.9Å; F464-F492 AromaticContact CZ-CE1 3.92Å; F464-F492 HydrophobicContact CZ-CE1 3.92Å; F464-F492 AromaticContact CZ-CE2 3.69Å; F464-F492 HydrophobicContact CZ-CE2 3.69Å; F464-F492 HydrophobicContact CZ-CG 4.12Å; F464-F492 AromaticContact CZ-CZ 3.72Å; F464-F492 HydrophobicContact CZ-CZ 3.72Å; V468-F492 HydrophobicContact CG2-CE2 4.07Å; F490-F492 HydrophobicContact CB-CE1 3.97Å; F490-F492 HydrophobicContact CB-CE2 4.46Å; F490-F492 HydrophobicContact CB-CZ 3.92Å; F490-F492 AromaticContact CD1-CE1 3.38Å; F490-F492 HydrophobicContact CD1-CE1 3.38Å; F490-F492 AromaticContact CD1-CZ 3.42Å; F490-F492 HydrophobicContact CD1-CZ 3.42Å; F490-F492 VanDerWaalsContact CD1-CZ 3.42Å; F490-F492 HydrophobicContact CE1-CE1 4.16Å; F490-F492 HydrophobicContact CE1-CZ 4.02Å; F490-F492 AromaticContact CG-CE1 3.95Å; F490-F492 HydrophobicContact CG-CE1 3.95Å; F490-F492 AromaticContact CG-CZ 3.73Å; F490-F492 HydrophobicContact CG-CZ 3.73Å; F490-F492 PolarHBondContact O-N 3.07Å; F492-L494 PolarHBondContact O-N 2.61Å; F492-C496 PolarHBondContact O-N 3.46Å; F492-L499 HydrophobicContact CD2-CD1 4.36Å
493L80.2Confident78.8Confident0 Ų040.3 Ų40.30%021%0.206CC..Hα-helixtrans-67.9-28.6175-67.8178.3000111.3V468 F490 H491 L499 M500 F503V468-L493 HydrophobicContact CG1-CD2 4.25Å; F490-L493 HydrophobicContact CB-CD1 3.72Å; F490-L493 HydrophobicContact CB-CG 3.98Å; F490-L493 HydrophobicContact CD2-CD1 3.91Å; F490-L493 HydrophobicContact CG-CD1 4.2Å; F490-L493 WeakPolarHBondContact O-CB 3.34Å; F490-L493 PolarHBondContact O-N 2.94Å; H491-L493 PolarHBondContact O-N 3.33Å; H491-L493 VanDerWaalsContact O-N 3.17Å; L493-L499 HydrophobicContact CD2-CB 3.97Å; L493-L499 HydrophobicContact CD2-CD1 4.21Å; L493-M500 WeakPolarHBondContact O-CA 3.44Å; L493-M500 VanDerWaalsContact O-CB 3.24Å; L493-M500 WeakPolarHBondContact O-CB 3.45Å; L493-M500 PolarHBondContact O-N 3.4Å; L493-M500 VanDerWaalsContact O-N 3.16Å; L493-F503 HydrophobicContact CD1-CD1 4.01Å; L493-F503 HydrophobicContact CD1-CD2 4.27Å; L493-F503 HydrophobicContact CD1-CE1 4.24Å; L493-F503 HydrophobicContact CD1-CG 4.02Å; L493-F503 HydrophobicContact CD1-CZ 4.5Å; L493-F503 HydrophobicContact CD2-CD2 3.73Å; L493-F503 HydrophobicContact CD2-CE2 3.72Å; L493-F503 HydrophobicContact CD2-CG 4.32Å; L493-F503 HydrophobicContact CD2-CZ 4.29Å
494L74.9Confident79Confident5 Ų539.8 Ų39.83%0.02620%0.2CC..Hα-helixtrans-89.5-26.9-179.3-53.1177.6000111.6I486 F487 H491 F492 I507 W518 L763I486-L494 HydrophobicContact CG2-CD1 3.6Å; I486-L494 HydrophobicContact CG2-CD2 4.15Å; I486-L494 HydrophobicContact CG2-CG 4.04Å; F487-L494 HydrophobicContact CD1-CD1 4.26Å; F487-L494 HydrophobicContact CE1-CD1 4.25Å; H491-L494 WeakPolarHBondContact O-CA 3.43Å; H491-L494 WeakPolarHBondContact O-CB 3.45Å; H491-L494 PolarHBondContact O-N 3.11Å; F492-L494 PolarHBondContact O-N 2.61Å; L494-I507 HydrophobicContact CD2-CD1 3.51Å; L494-I507 HydrophobicContact CD2-CG1 3.92Å; L494-I507 HydrophobicContact CD2-CG2 3.99Å; L494-W518 HydrophobicContact CB-CH2 3.27Å; L494-W518 HydrophobicContact CB-CZ2 3.37Å; L494-W518 HydrophobicContact CB-CZ3 4.03Å; L494-W518 HydrophobicContact CD1-CD2 3.54Å; L494-W518 HydrophobicContact CD1-CE3 3.87Å; L494-W518 HydrophobicContact CD1-CG 4.26Å; L494-W518 HydrophobicContact CD1-CH2 3.7Å; L494-W518 HydrophobicContact CD1-CZ2 3.3Å; L494-W518 HydrophobicContact CD1-CZ3 3.95Å; L494-W518 HydrophobicContact CG-CH2 4.1Å; L494-W518 HydrophobicContact CG-CZ2 3.93Å; L494-L763 HydrophobicContact CD2-CD2 3.87Å
495E72.6Confident79Confident93 Ų9339 Ų3944%0.43520%0.198SC..Hα-helixtrans-76.4-27.9176.9-67.3178.7161.300113.4Y448 H491Y448-E495 PolarHBondContact OH-OE2 3.1Å; H491-E495 IonicContact CD2-OE1 3.36Å; H491-E495 PolarHBondContact CD2-OE1 3.43Å; H491-E495 IonicContact CD2-OE2 3.49Å; H491-E495 PolarHBondContact O-N 3.44Å; H491-E495 VanDerWaalsContact O-N 3.09Å
496C76.6Confident78.9Confident6 Ų639.3 Ų39.34%0.04120%0.2CC..  trans-105.1112.2-174.9-174.10000111.5T460 F492 E498 L499 M500T460-C496 PolarHBondContact OG1-SG 3.34Å; F492-C496 PolarHBondContact O-N 3.46Å; C496-E498 VanDerWaalsContact C-N 3.3Å; C496-E498 PolarHBondContact O-N 3.42Å; C496-L499 HydrophobicContact CB-CB 4.19Å; C496-L499 HydrophobicContact CB-CD1 4.14Å; C496-L499 HydrophobicContact CB-CG 4.17Å; C496-L499 PolarHBondContact O-N 2.9Å; C496-L499 VanDerWaalsContact O-N 3.14Å; C496-M500 WeakPolarHBondContact O-CB 2.87Å; C496-M500 PolarHBondContact O-N 2.93Å
497P73.9Confident78.8Confident86 Ų8639.3 Ų39.356%0.55820%0.2SC*.Hα-helixtrans-56.8-38.5-175.7-27.434.9000114.6M500 S501P497-M500 PolarHBondContact O-N 2.87Å; P497-S501 PolarHBondContact O-N 3.46Å
498E76.9Confident78.7Confident126 Ų12639.4 Ų39.459%0.58920%0.2SC*.Hα-helixtrans-61.7-46.9178.5-65.5175.1-179.600111.2C496 S501C496-E498 VanDerWaalsContact C-N 3.3Å; C496-E498 PolarHBondContact O-N 3.42Å; E498-S501 PolarHBondContact O-OG 3.15Å
499L81.7Confident78.6Confident2 Ų240.2 Ų40.21%0.0121%0.205CC..Hα-helixtrans-71.5-41.6177.7-61-177.6000111.3I465 V468 F492 L493 C496 S501 R502 F503I465-L499 HydrophobicContact CG2-CD2 4.44Å; V468-L499 HydrophobicContact CB-CD1 4.43Å; V468-L499 HydrophobicContact CB-CD2 4.13Å; V468-L499 HydrophobicContact CG1-CD1 4.22Å; V468-L499 HydrophobicContact CG1-CD2 3.66Å; V468-L499 HydrophobicContact CG2-CD1 4.29Å; F492-L499 HydrophobicContact CD2-CD1 4.36Å; L493-L499 HydrophobicContact CD2-CB 3.97Å; L493-L499 HydrophobicContact CD2-CD1 4.21Å; C496-L499 HydrophobicContact CB-CB 4.19Å; C496-L499 HydrophobicContact CB-CD1 4.14Å; C496-L499 HydrophobicContact CB-CG 4.17Å; C496-L499 PolarHBondContact O-N 2.9Å; C496-L499 VanDerWaalsContact O-N 3.14Å; L499-S501 VanDerWaalsContact C-N 3.27Å; L499-S501 PolarHBondContact O-N 3.38Å; L499-R502 PolarHBondContact O-N 3.41Å; L499-F503 WeakPolarHBondContact O-CD2 3.47Å; L499-F503 PolarHBondContact O-N 3.19Å
500M79.4Confident78.5Confident6 Ų640.4 Ų40.43%0.0321%0.206CC..Hα-helixtrans-54.9-44.5179-168.117365.100111.3L493 C496 P497 R502 F503 M504 I507 S759 L763L493-M500 WeakPolarHBondContact O-CA 3.44Å; L493-M500 VanDerWaalsContact O-CB 3.24Å; L493-M500 WeakPolarHBondContact O-CB 3.45Å; L493-M500 PolarHBondContact O-N 3.4Å; L493-M500 VanDerWaalsContact O-N 3.16Å; C496-M500 WeakPolarHBondContact O-CB 2.87Å; C496-M500 PolarHBondContact O-N 2.93Å; P497-M500 PolarHBondContact O-N 2.87Å; M500-R502 VanDerWaalsContact C-N 3.3Å; M500-R502 PolarHBondContact O-N 3.39Å; M500-F503 CarbonylContact O-C 3.51Å; M500-F503 PolarHBondContact O-N 2.97Å; M500-M504 HydrophobicContact CE-CE 4.12Å; M500-M504 HydrophobicContact CG-CE 3.81Å; M500-M504 WeakPolarHBondContact O-CA 3.45Å; M500-M504 WeakPolarHBondContact O-CB 3.33Å; M500-M504 PolarHBondContact O-N 3.48Å; M500-M504 HydrophobicContact SD-CE 4.24Å; M500-I507 HydrophobicContact CG-CD1 4.21Å; M500-S759 WeakPolarHBondContact CE-O 3.32Å; M500-L763 HydrophobicContact SD-CD2 4.22Å
501S78.6Confident78.2Confident82 Ų8243.1 Ų43.157%0.57322%0.223SC*.Hα-helixtrans-58.9-38.1177.674.40000113.1P497 E498 L499P497-S501 PolarHBondContact O-N 3.46Å; E498-S501 PolarHBondContact O-OG 3.15Å; L499-S501 VanDerWaalsContact C-N 3.27Å; L499-S501 PolarHBondContact O-N 3.38Å
502R79.9Confident78.4Confident94 Ų9442.4 Ų42.436%0.35522%0.22SC..Hα-helixtrans-71.8-31.4-179.9-62.1-177.393.1-135-5.1112.5C469 D472 L499 M500C469-R502 PolarHBondContact SG-NH1 3.03Å; D472-R502 IonicContact OD2-CZ 2.73Å; D472-R502 IonicContact OD2-NH1 3.86Å; D472-R502 PolarHBondContact OD2-NH1 2.94Å; D472-R502 IonicContact OD2-NH2 3.5Å; D472-R502 PolarHBondContact OD2-NH2 3.37Å; L499-R502 PolarHBondContact O-N 3.41Å; M500-R502 VanDerWaalsContact C-N 3.3Å; M500-R502 PolarHBondContact O-N 3.39Å
503F82.6Confident78.5Confident1 Ų148.4 Ų48.40%0.00425%0.246CC..Hα-helixtrans-101.2-0.1-178.4-71.3-95.7000113.6V468 L475 K476 L493 L499 M500 H505 I506 I507V468-F503 HydrophobicContact CG1-CE2 4.09Å; V468-F503 HydrophobicContact CG1-CZ 4.45Å; L475-F503 HydrophobicContact CB-CE1 3.94Å; L475-F503 HydrophobicContact CB-CZ 3.89Å; L475-F503 HydrophobicContact CD1-CZ 4.39Å; K476-F503 HydrophobicContact CB-CE1 4.35Å; K476-F503 HydrophobicContact CG-CD1 3.95Å; K476-F503 HydrophobicContact CG-CE1 3.52Å; K476-F503 HydrophobicContact CG-CZ 4.22Å; L493-F503 HydrophobicContact CD1-CD1 4.01Å; L493-F503 HydrophobicContact CD1-CD2 4.27Å; L493-F503 HydrophobicContact CD1-CE1 4.24Å; L493-F503 HydrophobicContact CD1-CG 4.02Å; L493-F503 HydrophobicContact CD1-CZ 4.5Å; L493-F503 HydrophobicContact CD2-CD2 3.73Å; L493-F503 HydrophobicContact CD2-CE2 3.72Å; L493-F503 HydrophobicContact CD2-CG 4.32Å; L493-F503 HydrophobicContact CD2-CZ 4.29Å; L499-F503 WeakPolarHBondContact O-CD2 3.47Å; L499-F503 PolarHBondContact O-N 3.19Å; M500-F503 CarbonylContact O-C 3.51Å; M500-F503 PolarHBondContact O-N 2.97Å; F503-H505 VanDerWaalsContact C-N 3.28Å; F503-H505 PolarHBondContact O-N 3.39Å; F503-H505 VanDerWaalsContact O-N 3.16Å; F503-I506 HydrophobicContact CD1-CD1 4.42Å; F503-I506 PolarHBondContact O-N 2.92Å; F503-I507 HydrophobicContact CB-CD1 3.87Å; F503-I507 HydrophobicContact CB-CG1 4.29Å; F503-I507 WeakPolarHBondContact O-CG1 3.18Å; F503-I507 PolarHBondContact O-N 3.14Å
504M78.4Confident78.5Confident36 Ų3650.6 Ų50.618%0.17726%0.257CS..Hα-helixtrans-53.6-41.3-171.9-172.260.876.600113.4M500 I506 I507 K508 Q762M500-M504 HydrophobicContact CE-CE 4.12Å; M500-M504 HydrophobicContact CG-CE 3.81Å; M500-M504 WeakPolarHBondContact O-CA 3.45Å; M500-M504 WeakPolarHBondContact O-CB 3.33Å; M500-M504 PolarHBondContact O-N 3.48Å; M500-M504 HydrophobicContact SD-CE 4.24Å; M504-I506 VanDerWaalsContact C-N 3.31Å; M504-I506 PolarHBondContact O-N 3.24Å; M504-I507 PolarHBondContact O-N 3.33Å; M504-K508 HydrophobicContact CG-CD 4.34Å; M504-K508 HydrophobicContact CG-CG 4.42Å; M504-K508 WeakPolarHBondContact O-CG 3.49Å; M504-K508 PolarHBondContact O-N 3.45Å; M504-K508 HydrophobicContact SD-CD 4.4Å; M504-K508 HydrophobicContact SD-CG 4.16Å; M504-Q762 HydrophobicContact CE-CB 4.24Å
505H78.6Confident79Confident108 Ų10850.5 Ų50.550%0.526%0.257SS..Hα-helixtrans-60.6-39.617868.8-77.5000112.5F503 N509F503-H505 VanDerWaalsContact C-N 3.28Å; F503-H505 PolarHBondContact O-N 3.39Å; F503-H505 VanDerWaalsContact O-N 3.16Å; H505-N509 PolarHBondContact O-N 3.02Å; H505-N509 PolarHBondContact O-ND2 3Å
506I79.2Confident79.6Confident8 Ų846.9 Ų46.94%0.04124%0.242CC..Hα-helixtrans-76-38.2178.3-48.9-174.9000110.4K476 V479 F503 M504 N509 Q510K476-I506 HydrophobicContact CB-CD1 3.51Å; K476-I506 HydrophobicContact CD-CD1 4.29Å; K476-I506 HydrophobicContact CG-CD1 3.55Å; V479-I506 HydrophobicContact CB-CG2 4.09Å; V479-I506 HydrophobicContact CG1-CB 4.41Å; V479-I506 HydrophobicContact CG1-CG2 3.34Å; F503-I506 HydrophobicContact CD1-CD1 4.42Å; F503-I506 PolarHBondContact O-N 2.92Å; M504-I506 VanDerWaalsContact C-N 3.31Å; M504-I506 PolarHBondContact O-N 3.24Å; I506-N509 PolarHBondContact O-N 2.72Å; I506-Q510 WeakPolarHBondContact O-CG 3.34Å; I506-Q510 PolarHBondContact O-NE2 3.16Å
507I80Confident79.9Confident0 Ų051 Ų510%026%0.261CS..Hα-helixtrans-61.7-44.4177.7-66.1161.4000110.5I486 L494 M500 F503 M504 N509 Q510 R515 L763I486-I507 HydrophobicContact CD1-CG1 3.81Å; L494-I507 HydrophobicContact CD2-CD1 3.51Å; L494-I507 HydrophobicContact CD2-CG1 3.92Å; L494-I507 HydrophobicContact CD2-CG2 3.99Å; M500-I507 HydrophobicContact CG-CD1 4.21Å; F503-I507 HydrophobicContact CB-CD1 3.87Å; F503-I507 HydrophobicContact CB-CG1 4.29Å; F503-I507 WeakPolarHBondContact O-CG1 3.18Å; F503-I507 PolarHBondContact O-N 3.14Å; M504-I507 PolarHBondContact O-N 3.33Å; I507-N509 VanDerWaalsContact C-N 3.28Å; I507-N509 PolarHBondContact O-N 3.02Å; I507-Q510 WeakPolarHBondContact O-CB 3.32Å; I507-Q510 WeakPolarHBondContact O-CG 3.22Å; I507-Q510 PolarHBondContact O-N 3.38Å; I507-Q510 VanDerWaalsContact O-N 3.11Å; I507-R515 VanDerWaalsContact O-CD 3.28Å; I507-R515 WeakPolarHBondContact O-CD 3.22Å; I507-R515 PolarHBondContact O-NE 3.14Å; I507-L763 HydrophobicContact CG2-CD2 3.64Å
508K75.9Confident80.3Confident36 Ų3647.3 Ų47.316%0.15724%0.235CC..Hα-helixtrans-67.7-27.4177.9-72.3-169.1170.1-155.70113.4M504 Q510 R515 Q762 F764M504-K508 HydrophobicContact CG-CD 4.34Å; M504-K508 HydrophobicContact CG-CG 4.42Å; M504-K508 WeakPolarHBondContact O-CG 3.49Å; M504-K508 PolarHBondContact O-N 3.45Å; M504-K508 HydrophobicContact SD-CD 4.4Å; M504-K508 HydrophobicContact SD-CG 4.16Å; K508-Q510 PolarHBondContact O-N 3.44Å; K508-R515 PolarHBondContact O-NH2 2.72Å; K508-Q762 WeakPolarHBondContact CE-O 3.32Å; K508-F764 PolarHBondContact NZ-O 3.31Å
509N76.3Confident80.6Confident115 Ų11541.3 Ų41.362%0.61521%0.207SC*.THydrogen-bonded Turntrans-74-4.2173.8-69.2-16.3000113.7H505 I506 I507H505-N509 PolarHBondContact O-N 3.02Å; H505-N509 PolarHBondContact O-ND2 3Å; I506-N509 PolarHBondContact O-N 2.72Å; I507-N509 VanDerWaalsContact C-N 3.28Å; I507-N509 PolarHBondContact O-N 3.02Å
510Q78.8Confident80.8Confident8 Ų842.3 Ų42.34%0.03721%0.211CC..SBendtrans-75.1150.4176.1-55.2-54.4-57.200111P483 I486 F487 I506 I507 K508 F512 R515P483-Q510 VanDerWaalsContact C-OE1 3.28Å; P483-Q510 PolarHBondContact O-OE1 3.12Å; P483-Q510 VanDerWaalsContact O-OE1 3.09Å; I486-Q510 HydrophobicContact CD1-CG 3.87Å; F487-Q510 HydrophobicContact CE2-CB 4.22Å; F487-Q510 HydrophobicContact CE2-CG 4.43Å; F487-Q510 HydrophobicContact CZ-CB 4.17Å; F487-Q510 HydrophobicContact CZ-CG 4.39Å; I506-Q510 WeakPolarHBondContact O-CG 3.34Å; I506-Q510 PolarHBondContact O-NE2 3.16Å; I507-Q510 WeakPolarHBondContact O-CB 3.32Å; I507-Q510 WeakPolarHBondContact O-CG 3.22Å; I507-Q510 PolarHBondContact O-N 3.38Å; I507-Q510 VanDerWaalsContact O-N 3.11Å; K508-Q510 PolarHBondContact O-N 3.44Å; Q510-F512 PolarHBondContact O-N 3.48Å; Q510-R515 HydrophobicContact CB-CG 4.15Å; Q510-R515 PolarHBondContact O-NE 3.16Å; Q510-R515 PolarHBondContact O-NH2 3.35Å
511P80.6Confident80.8Confident57 Ų5747.9 Ų47.937%0.3724%0.237SC..  trans-51134.5177.1-26.434.8000112.4K513 D514 R515P511-K513 VanDerWaalsContact C-N 3.27Å; P511-K513 PolarHBondContact O-N 3.18Å; P511-D514 HydrophobicContact CB-CB 4.45Å; P511-D514 PolarHBondContact O-N 3.35Å; P511-R515 PolarHBondContact O-N 2.93Å
512F81.8Confident80.7Confident20 Ų2046.6 Ų46.69%0.08822%0.222CC..Hα-helixtrans-56.4-42.9-177.5171-110.9000111.8Q510 D514 R515 C516 F764 E768 L771 L772 M776Q510-F512 PolarHBondContact O-N 3.48Å; F512-D514 PolarHBondContact O-N 2.74Å; F512-R515 PolarHBondContact O-N 2.97Å; F512-C516 WeakPolarHBondContact CE2-SG 3.27Å; F512-C516 WeakPolarHBondContact CZ-SG 3.47Å; F512-C516 PolarHBondContact O-N 3.44Å; F512-C516 PolarHBondContact O-SG 2.76Å; F512-F764 AromaticContact CD2-CD1 3.96Å; F512-F764 HydrophobicContact CD2-CD1 3.96Å; F512-F764 HydrophobicContact CD2-CE1 4.04Å; F512-F764 AromaticContact CE2-CD1 3.79Å; F512-F764 HydrophobicContact CE2-CD1 3.79Å; F512-F764 AromaticContact CE2-CE1 3.87Å; F512-F764 HydrophobicContact CE2-CE1 3.87Å; F512-E768 HydrophobicContact CD2-CB 3.77Å; F512-E768 HydrophobicContact CD2-CG 3.66Å; F512-E768 HydrophobicContact CE2-CB 3.65Å; F512-E768 HydrophobicContact CE2-CG 4.05Å; F512-E768 HydrophobicContact CG-CG 4.45Å; F512-L771 HydrophobicContact CE1-CB 4.23Å; F512-L771 HydrophobicContact CZ-CB 3.91Å; F512-L772 HydrophobicContact CZ-CB 4.46Å; F512-M776 HydrophobicContact CD1-CE 3.93Å; F512-M776 HydrophobicContact CE1-CE 4.11Å
513K82.4Confident80.7Confident127 Ų12743.1 Ų43.155%0.55221%0.21SC*.Hα-helixtrans-58.5-47.7178.9-171.8-176.6175.8-169.30113.2P511 R515 C516 E517P511-K513 VanDerWaalsContact C-N 3.27Å; P511-K513 PolarHBondContact O-N 3.18Å; K513-R515 VanDerWaalsContact C-N 3.32Å; K513-R515 PolarHBondContact O-N 3.07Å; K513-C516 WeakPolarHBondContact O-CB 3.36Å; K513-C516 PolarHBondContact O-N 3.45Å; K513-C516 VanDerWaalsContact O-N 3.17Å; K513-E517 VanDerWaalsContact CE-OE1 3.23Å; K513-E517 WeakPolarHBondContact CE-OE1 3.41Å; K513-E517 IonicContact NZ-OE1 3.51Å; K513-E517 PolarHBondContact O-N 2.9Å
514D80.4Confident80.3Confident46 Ų4646.1 Ų46.125%0.24623%0.226CC..Hα-helixtrans-65.4-39-178.1-64-15.7000110.6F487 P511 F512 E517 W518F487-D514 HydrophobicContact CD2-CB 4.14Å; F487-D514 HydrophobicContact CE2-CB 3.7Å; F487-D514 HydrophobicContact CZ-CB 4.29Å; P511-D514 HydrophobicContact CB-CB 4.45Å; P511-D514 PolarHBondContact O-N 3.35Å; F512-D514 PolarHBondContact O-N 2.74Å; D514-E517 PolarHBondContact O-N 2.86Å; D514-W518 PolarHBondContact O-N 3.2Å
515R85.3Confident79.4Confident3 Ų348.3 Ų48.31%0.01125%0.25CS..Hα-helixtrans-63.7-38.9172.8-78.3-171.3-79.7131.75.6112.8F487 I507 K508 Q510 P511 F512 K513 F519 L763 F764 E768F487-R515 HydrophobicContact CE1-CG 4.15Å; F487-R515 HydrophobicContact CZ-CB 4.45Å; F487-R515 HydrophobicContact CZ-CG 3.6Å; I507-R515 VanDerWaalsContact O-CD 3.28Å; I507-R515 WeakPolarHBondContact O-CD 3.22Å; I507-R515 PolarHBondContact O-NE 3.14Å; K508-R515 PolarHBondContact O-NH2 2.72Å; Q510-R515 HydrophobicContact CB-CG 4.15Å; Q510-R515 PolarHBondContact O-NE 3.16Å; Q510-R515 PolarHBondContact O-NH2 3.35Å; P511-R515 PolarHBondContact O-N 2.93Å; F512-R515 PolarHBondContact O-N 2.97Å; K513-R515 VanDerWaalsContact C-N 3.32Å; K513-R515 PolarHBondContact O-N 3.07Å; R515-F519 VanDerWaalsContact O-CB 3.22Å; R515-F519 WeakPolarHBondContact O-CB 3.48Å; R515-F519 PolarHBondContact O-N 3.31Å; R515-L763 PolarHBondContact NH1-O 2.92Å; R515-F764 HydrophobicContact CB-CE1 3.88Å; R515-F764 HydrophobicContact CB-CZ 4.31Å; R515-E768 IonicContact CZ-OE1 2.81Å; R515-E768 IonicContact CZ-OE2 3.73Å; R515-E768 IonicContact NH1-OE1 2.73Å; R515-E768 IonicContact NH1-OE2 2.97Å; R515-E768 PolarHBondContact NH1-OE2 3.4Å; R515-E768 IonicContact NH2-OE1 3.33Å; R515-E768 PolarHBondContact NH2-OE1 2.85Å; R515-E768 IonicContact NH2-OE2 2.82Å; R515-E768 PolarHBondContact NH2-OE2 3.36Å
516C84.4Confident78.1Confident18 Ų1846.9 Ų46.912%0.12226%0.264CS..Hα-helixtrans-64.1-46175.6-69.80000112.1F512 K513 F519 Y520F512-C516 WeakPolarHBondContact CE2-SG 3.27Å; F512-C516 WeakPolarHBondContact CZ-SG 3.47Å; F512-C516 PolarHBondContact O-N 3.44Å; F512-C516 PolarHBondContact O-SG 2.76Å; K513-C516 WeakPolarHBondContact O-CB 3.36Å; K513-C516 PolarHBondContact O-N 3.45Å; K513-C516 VanDerWaalsContact O-N 3.17Å; C516-F519 WeakPolarHBondContact O-CB 3.36Å; C516-F519 PolarHBondContact O-N 3.49Å; C516-Y520 WeakPolarHBondContact O-CD2 3.31Å; C516-Y520 PolarHBondContact O-N 2.86Å; C516-Y520 VanDerWaalsContact O-N 3.1Å
517E83.8Confident76.9Confident93 Ų9350.1 Ų50.144%0.43528%0.279SS..Hα-helixtrans-58.5-50.4177.6-73179.4-175.600110.4K513 D514 F519 Y520 E521K513-E517 VanDerWaalsContact CE-OE1 3.23Å; K513-E517 WeakPolarHBondContact CE-OE1 3.41Å; K513-E517 IonicContact NZ-OE1 3.51Å; K513-E517 PolarHBondContact O-N 2.9Å; D514-E517 PolarHBondContact O-N 2.86Å; E517-F519 PolarHBondContact O-N 3.45Å; E517-Y520 PolarHBondContact O-N 3.11Å; E517-E521 WeakPolarHBondContact O-CG 3.4Å; E517-E521 PolarHBondContact O-N 3.27Å
518W80.9Confident75.1Confident7 Ų755.4 Ų55.43%0.02731%0.313CS..Hα-helixtrans-61.1-43.2177.5-17390.5000113F487 L494 D514 Y520 E521 H522 L760 L763F487-W518 HydrophobicContact CD1-CB 3.53Å; F487-W518 AromaticContact CD1-CD1 3.43Å; F487-W518 VanDerWaalsContact CD1-CD1 3.43Å; F487-W518 HydrophobicContact CD1-CD2 4.29Å; F487-W518 AromaticContact CD1-CG 3.44Å; F487-W518 HydrophobicContact CD1-CG 3.44Å; F487-W518 VanDerWaalsContact CD1-CG 3.44Å; F487-W518 HydrophobicContact CE1-CB 3.75Å; F487-W518 AromaticContact CE1-CG 3.89Å; F487-W518 HydrophobicContact CE1-CG 3.89Å; F487-W518 HydrophobicContact CG-CB 4.45Å; L494-W518 HydrophobicContact CB-CH2 3.27Å; L494-W518 HydrophobicContact CB-CZ2 3.37Å; L494-W518 HydrophobicContact CB-CZ3 4.03Å; L494-W518 HydrophobicContact CD1-CD2 3.54Å; L494-W518 HydrophobicContact CD1-CE3 3.87Å; L494-W518 HydrophobicContact CD1-CG 4.26Å; L494-W518 HydrophobicContact CD1-CH2 3.7Å; L494-W518 HydrophobicContact CD1-CZ2 3.3Å; L494-W518 HydrophobicContact CD1-CZ3 3.95Å; L494-W518 HydrophobicContact CG-CH2 4.1Å; L494-W518 HydrophobicContact CG-CZ2 3.93Å; D514-W518 PolarHBondContact O-N 3.2Å; W518-Y520 VanDerWaalsContact C-N 3.29Å; W518-Y520 PolarHBondContact O-N 3.26Å; W518-E521 PolarHBondContact O-N 2.91Å; W518-H522 AromaticContact CD1-CE1 3.4Å; W518-H522 VanDerWaalsContact CD1-CE1 3.4Å; W518-H522 AromaticContact CD1-ND1 3.61Å; W518-H522 AromaticContact CD2-CE1 3.83Å; W518-H522 AromaticContact CD2-CG 3.97Å; W518-H522 AromaticContact CD2-ND1 3.44Å; W518-H522 AromaticContact CE2-CD2 3.72Å; W518-H522 AromaticContact CE2-CE1 3.1Å; W518-H522 AromaticContact CE2-CG 3.57Å; W518-H522 AromaticContact CE2-ND1 3.15Å; W518-H522 AromaticContact CE2-NE2 3.43Å; W518-H522 HydrophobicContact CE3-CB 4.47Å; W518-H522 AromaticContact CG-CE1 3.99Å; W518-H522 AromaticContact CG-ND1 3.75Å; W518-H522 HydrophobicContact CH2-CB 4.07Å; W518-H522 AromaticContact CH2-CD2 3.68Å; W518-H522 AromaticContact CH2-CG 3.61Å; W518-H522 HydrophobicContact CZ2-CB 4.32Å; W518-H522 AromaticContact CZ2-CD2 3.22Å; W518-H522 WeakPolarHBondContact CZ2-CD2 3.34Å; W518-H522 AromaticContact CZ2-CE1 3.47Å; W518-H522 VanDerWaalsContact CZ2-CE1 3.47Å; W518-H522 WeakPolarHBondContact CZ2-CE1 3.35Å; W518-H522 AromaticContact CZ2-CG 3.38Å; W518-H522 AromaticContact CZ2-ND1 3.5Å; W518-H522 AromaticContact CZ2-NE2 3.27Å; W518-H522 VanDerWaalsContact CZ2-NE2 3.27Å; W518-H522 WeakPolarHBondContact CZ2-NE2 3.45Å; W518-H522 HydrophobicContact CZ3-CB 4.16Å; W518-H522 AromaticContact NE1-CE1 2.89Å; W518-H522 PolarHBondContact NE1-CE1 3.33Å; W518-H522 AromaticContact NE1-ND1 3.36Å; W518-H522 PolarHBondContact NE1-ND1 2.99Å; W518-H522 AromaticContact NE1-NE2 3.45Å; W518-H522 PolarHBondContact NE1-NE2 3.4Å; W518-H522 PolarHBondContact O-N 3.05Å; W518-H522 PolarHBondContact O-ND1 3.35Å; W518-L760 HydrophobicContact CH2-CD2 3.94Å; W518-L760 HydrophobicContact CZ3-CD2 3.57Å; W518-L763 HydrophobicContact CE3-CD1 3.72Å; W518-L763 HydrophobicContact CZ3-CD1 3.59Å
519F84.6Confident73.4Confident0 Ų061.5 Ų61.50%035%0.348CS..Hα-helixtrans-53.5-47.4176.4166.7-94.2000110.9R515 C516 E517 L523 L640 I756 L760 I761 F764 L772R515-F519 VanDerWaalsContact O-CB 3.22Å; R515-F519 WeakPolarHBondContact O-CB 3.48Å; R515-F519 PolarHBondContact O-N 3.31Å; C516-F519 WeakPolarHBondContact O-CB 3.36Å; C516-F519 PolarHBondContact O-N 3.49Å; E517-F519 PolarHBondContact O-N 3.45Å; F519-L523 HydrophobicContact CE1-CD2 3.95Å; F519-L523 HydrophobicContact CZ-CD2 4.05Å; F519-L523 WeakPolarHBondContact O-CB 3.23Å; F519-L523 PolarHBondContact O-N 2.87Å; F519-L640 HydrophobicContact CE1-CD1 4.17Å; F519-L640 HydrophobicContact CE1-CD2 4.31Å; F519-L640 HydrophobicContact CE1-CG 4.13Å; F519-L640 HydrophobicContact CZ-CD2 3.88Å; F519-L640 HydrophobicContact CZ-CG 4.13Å; F519-I756 HydrophobicContact CE2-CG2 4.11Å; F519-I756 HydrophobicContact CZ-CD1 4.31Å; F519-I756 HydrophobicContact CZ-CG2 4Å; F519-L760 HydrophobicContact CD2-CB 3.86Å; F519-L760 HydrophobicContact CE2-CB 3.81Å; F519-I761 HydrophobicContact CE2-CD1 4.39Å; F519-F764 HydrophobicContact CB-CE2 4.13Å; F519-F764 HydrophobicContact CB-CZ 3.96Å; F519-F764 AromaticContact CD2-CE2 3.83Å; F519-F764 HydrophobicContact CD2-CE2 3.83Å; F519-F764 HydrophobicContact CE2-CE2 4.44Å; F519-F764 AromaticContact CG-CE2 3.99Å; F519-F764 HydrophobicContact CG-CE2 3.99Å; F519-F764 HydrophobicContact CG-CZ 4.23Å; F519-L772 HydrophobicContact CE1-CD2 4.47Å
520Y84.6Confident71.6Confident23 Ų2360 Ų609%0.0935%0.346CS..Hα-helixtrans-74.3-36.8-179.7-75.2-62000113.9C516 E517 W518 H522 L523 L524 L640 R643 L772C516-Y520 WeakPolarHBondContact O-CD2 3.31Å; C516-Y520 PolarHBondContact O-N 2.86Å; C516-Y520 VanDerWaalsContact O-N 3.1Å; E517-Y520 PolarHBondContact O-N 3.11Å; W518-Y520 VanDerWaalsContact C-N 3.29Å; W518-Y520 PolarHBondContact O-N 3.26Å; Y520-H522 VanDerWaalsContact C-N 3.28Å; Y520-H522 PolarHBondContact O-N 3.23Å; Y520-L523 HydrophobicContact CD1-CD2 4.35Å; Y520-L523 PolarHBondContact O-N 3.21Å; Y520-L524 WeakPolarHBondContact O-CB 3.27Å; Y520-L524 VanDerWaalsContact O-CG 3.28Å; Y520-L524 WeakPolarHBondContact O-CG 3.47Å; Y520-L524 PolarHBondContact O-N 3.43Å; Y520-L524 VanDerWaalsContact O-N 3.13Å; Y520-L640 HydrophobicContact CE1-CD1 4.47Å; Y520-L640 VanDerWaalsContact CE1-O 3.27Å; Y520-L640 WeakPolarHBondContact CE1-O 3.46Å; Y520-L640 WeakPolarHBondContact OH-CD1 3.32Å; Y520-L640 PolarHBondContact OH-O 3.08Å; Y520-R643 HydrophobicContact CD1-CG 3.87Å; Y520-R643 HydrophobicContact CE1-CG 3.52Å; Y520-R643 HydrophobicContact CE2-CG 4.22Å; Y520-R643 HydrophobicContact CG-CG 4.37Å; Y520-L772 HydrophobicContact CE2-CD1 4.32Å
521E80.8Confident69.5Low123 Ų12365.9 Ų65.958%0.57538%0.378SS*.Hα-helixtrans-57.1-45.1173.4-74.8179.8171.600110.7E517 W518 L524 A525E517-E521 WeakPolarHBondContact O-CG 3.4Å; E517-E521 PolarHBondContact O-N 3.27Å; W518-E521 PolarHBondContact O-N 2.91Å; E521-L524 CarbonylContact O-C 3.57Å; E521-L524 PolarHBondContact O-N 2.97Å; E521-A525 WeakPolarHBondContact O-CA 3.45Å; E521-A525 WeakPolarHBondContact O-CB 3.25Å; E521-A525 PolarHBondContact O-N 3.37Å
522H75.8Confident67.7Low55 Ų5570.4 Ų70.426%0.25540%0.396SS..Hα-helixtrans-77.1-33.6-178.1-72.765.9000113W518 Y520 L524 A525W518-H522 AromaticContact CD1-CE1 3.4Å; W518-H522 VanDerWaalsContact CD1-CE1 3.4Å; W518-H522 AromaticContact CD1-ND1 3.61Å; W518-H522 AromaticContact CD2-CE1 3.83Å; W518-H522 AromaticContact CD2-CG 3.97Å; W518-H522 AromaticContact CD2-ND1 3.44Å; W518-H522 AromaticContact CE2-CD2 3.72Å; W518-H522 AromaticContact CE2-CE1 3.1Å; W518-H522 AromaticContact CE2-CG 3.57Å; W518-H522 AromaticContact CE2-ND1 3.15Å; W518-H522 AromaticContact CE2-NE2 3.43Å; W518-H522 HydrophobicContact CE3-CB 4.47Å; W518-H522 AromaticContact CG-CE1 3.99Å; W518-H522 AromaticContact CG-ND1 3.75Å; W518-H522 HydrophobicContact CH2-CB 4.07Å; W518-H522 AromaticContact CH2-CD2 3.68Å; W518-H522 AromaticContact CH2-CG 3.61Å; W518-H522 HydrophobicContact CZ2-CB 4.32Å; W518-H522 AromaticContact CZ2-CD2 3.22Å; W518-H522 WeakPolarHBondContact CZ2-CD2 3.34Å; W518-H522 AromaticContact CZ2-CE1 3.47Å; W518-H522 VanDerWaalsContact CZ2-CE1 3.47Å; W518-H522 WeakPolarHBondContact CZ2-CE1 3.35Å; W518-H522 AromaticContact CZ2-CG 3.38Å; W518-H522 AromaticContact CZ2-ND1 3.5Å; W518-H522 AromaticContact CZ2-NE2 3.27Å; W518-H522 VanDerWaalsContact CZ2-NE2 3.27Å; W518-H522 WeakPolarHBondContact CZ2-NE2 3.45Å; W518-H522 HydrophobicContact CZ3-CB 4.16Å; W518-H522 AromaticContact NE1-CE1 2.89Å; W518-H522 PolarHBondContact NE1-CE1 3.33Å; W518-H522 AromaticContact NE1-ND1 3.36Å; W518-H522 PolarHBondContact NE1-ND1 2.99Å; W518-H522 AromaticContact NE1-NE2 3.45Å; W518-H522 PolarHBondContact NE1-NE2 3.4Å; W518-H522 PolarHBondContact O-N 3.05Å; W518-H522 PolarHBondContact O-ND1 3.35Å; Y520-H522 VanDerWaalsContact C-N 3.28Å; Y520-H522 PolarHBondContact O-N 3.23Å; H522-L524 PolarHBondContact O-N 3.19Å; H522-A525 PolarHBondContact O-N 3.48Å
523L79Confident65.5Low21 Ų2174.5 Ų74.511%0.1142%0.423CS..Hα-helixtrans-62.3-29173-171.164.8000112F519 Y520 Y641 I756 L760F519-L523 HydrophobicContact CE1-CD2 3.95Å; F519-L523 HydrophobicContact CZ-CD2 4.05Å; F519-L523 WeakPolarHBondContact O-CB 3.23Å; F519-L523 PolarHBondContact O-N 2.87Å; Y520-L523 HydrophobicContact CD1-CD2 4.35Å; Y520-L523 PolarHBondContact O-N 3.21Å; L523-Y641 HydrophobicContact CD1-CD2 3.98Å; L523-Y641 HydrophobicContact CD1-CE2 4.11Å; L523-Y641 HydrophobicContact CD2-CD2 3.71Å; L523-Y641 HydrophobicContact CD2-CE2 4.28Å; L523-Y641 HydrophobicContact CD2-CG 4.36Å; L523-Y641 HydrophobicContact CG-CD2 3.72Å; L523-Y641 HydrophobicContact CG-CE2 3.8Å; L523-I756 HydrophobicContact CD1-CD1 4.19Å; L523-I756 HydrophobicContact CD2-CD1 3.78Å; L523-L760 HydrophobicContact CD1-CD1 4.3Å
524L75.8Confident63.7Low64 Ų6476.8 Ų76.834%0.33544%0.435SS..Hα-helixtrans-103.2-4.5-178.1-60.6174.4000114.1Y520 E521 H522 G526 Q527 Y641Y520-L524 WeakPolarHBondContact O-CB 3.27Å; Y520-L524 VanDerWaalsContact O-CG 3.28Å; Y520-L524 WeakPolarHBondContact O-CG 3.47Å; Y520-L524 PolarHBondContact O-N 3.43Å; Y520-L524 VanDerWaalsContact O-N 3.13Å; E521-L524 CarbonylContact O-C 3.57Å; E521-L524 PolarHBondContact O-N 2.97Å; H522-L524 PolarHBondContact O-N 3.19Å; L524-G526 PolarHBondContact O-N 2.81Å; L524-Q527 PolarHBondContact O-N 3.25Å; L524-Y641 HydrophobicContact CD2-CE1 4.22Å
525A58.3Low62Low83 Ų8383.5 Ų83.569%0.68646%0.457SS*.THydrogen-bonded Turntrans-62.510.9-170.600000117.2E521 H522E521-A525 WeakPolarHBondContact O-CA 3.45Å; E521-A525 WeakPolarHBondContact O-CB 3.25Å; E521-A525 PolarHBondContact O-N 3.37Å; H522-A525 PolarHBondContact O-N 3.48Å
526G51.8Low60.2Low77 Ų7788.6 Ų88.679%0.79449%0.49SS*.THydrogen-bonded Turntrans-124.62.917400000114.7L524L524-G526 PolarHBondContact O-N 2.81Å
527Q54.1Low58.9Low76 Ų7692 Ų9236%0.35551%0.51SS..SBendtrans-100.3132.4177.2-65.2-88.2-14.800108.9L524 D529L524-Q527 PolarHBondContact O-N 3.25Å; Q527-D529 PolarHBondContact O-N 3.15Å
528P42.9Very low57.7Low111 Ų11192.4 Ų92.472%0.72152%0.515SS*.  trans-58.6132.7168.925.6-31.1000107.9S530P528-S530 VanDerWaalsContact C-N 3.29Å; P528-S530 PolarHBondContact O-N 3.2Å
529D39Very low56.9Low164 Ų16499.7 Ų99.788%0.87755%0.55SS*.  trans-27.189.8179.6-90.7-31.7000111.3Q527 D531Q527-D529 PolarHBondContact O-N 3.15Å; D529-D531 PolarHBondContact O-N 3.2Å; D529-D531 VanDerWaalsContact O-N 3.12Å
530S38.5Very low55.8Low83 Ų83104.3 Ų104.358%0.5858%0.582SS**  trans-90.370.3170.882.10000104.6P528 M532P528-S530 VanDerWaalsContact C-N 3.29Å; P528-S530 PolarHBondContact O-N 3.2Å; S530-M532 PolarHBondContact O-N 3.07Å
531D35.6Very low55.1Low133 Ų133106.3 Ų106.371%0.71159%0.594SS**  trans-43.4120.3145.1-91.7-21.2000105.2D529 V533D529-D531 PolarHBondContact O-N 3.2Å; D529-D531 VanDerWaalsContact O-N 3.12Å; D531-V533 HydrophobicContact CB-CG2 4.22Å; D531-V533 PolarHBondContact O-N 3.35Å
532M42Very low55Low151 Ų151101.2 Ų101.274%0.74457%0.57SS**SBendtrans-67.943-177.2-67.4174.662.400111.6S530S530-M532 PolarHBondContact O-N 3.07Å
533V36.7Very low55.4Low107 Ų10799 Ų9965%0.64856%0.561SS**SBendtrans-101.295.4178.6-175.40000107.4D531D531-V533 HydrophobicContact CB-CG2 4.22Å; D531-V533 PolarHBondContact O-N 3.35Å
534H42.9Very low55.7Low174 Ų174102 Ų10281%0.80658%0.576SS**  trans50.369.3156-62.9-65.7000116.9
535R45.9Very low56.3Low188 Ų18898.9 Ų98.971%0.70956%0.56SS**  trans-76.4128.4151.7-158.1179.1-161.1-172.24.8108.4V537R535-V537 PolarHBondContact O-N 2.79Å; R535-V537 VanDerWaalsContact O-N 3.09Å
536P47.5Very low57.7Low110 Ų11098.8 Ų98.871%0.71455%0.545SS*.  trans-63.1114.2170.923.9-29.8000108.5N538P536-N538 PolarHBondContact O-N 2.91Å
537V55.5Low59.3Low88 Ų8899.7 Ų99.753%0.53353%0.525SS..  trans-72.9117178.2-178.30000107.7R535 I542 A571R535-V537 PolarHBondContact O-N 2.79Å; R535-V537 VanDerWaalsContact O-N 3.09Å; V537-I542 HydrophobicContact CG1-CG1 3.92Å; V537-A571 HydrophobicContact CG1-CB 3.75Å
538N60.4Low60.7Low103 Ų103103.9 Ų103.955%0.55155%0.549SS*.  trans-68.3144.3171.7-71.7-27.9000109.6P536 S540 D541P536-N538 PolarHBondContact O-N 2.91Å; N538-S540 PolarHBondContact O-N 2.87Å; N538-D541 PolarHBondContact O-N 3.41Å
539E62.5Low62.7Low160 Ų160101 Ų10175%0.74853%0.532SS*.G310 helixtrans-58.8-25.6-178.5-73.1-169.9147.400113.8D541 I542E539-D541 VanDerWaalsContact C-N 3.26Å; E539-D541 PolarHBondContact O-N 2.87Å; E539-I542 HydrophobicContact CB-CD1 4.49Å
540S62.2Low65Low96 Ų9693.8 Ų93.867%0.67149%0.493SS*.G310 helixtrans-72.8-12.9178.1580000114.8N538N538-S540 PolarHBondContact O-N 2.87Å
541D70.1Confident67.4Low66 Ų6689.8 Ų89.835%0.35347%0.465SS..G310 helixtrans-104.810.5-177.1-59.8-40.4000112.3N538 E539 K565N538-D541 PolarHBondContact O-N 3.41Å; E539-D541 VanDerWaalsContact C-N 3.26Å; E539-D541 PolarHBondContact O-N 2.87Å; D541-K565 IonicContact OD1-NZ 3.12Å; D541-K565 PolarHBondContact OD1-NZ 3.27Å
542I79.5Confident69.8Low15 Ų1590.7 Ų90.78%0.07746%0.459CS..EExtended strand (participates in β ladder)trans-92.3125.9178.7-57.8166000109.7V537 E539 L544 A571 R573 M580V537-I542 HydrophobicContact CG1-CG1 3.92Å; E539-I542 HydrophobicContact CB-CD1 4.49Å; I542-L544 PolarHBondContact O-N 3.05Å; I542-A571 HydrophobicContact CG1-CB 4.38Å; I542-R573 HydrophobicContact CG2-CB 3.62Å; I542-M580 HydrophobicContact CB-CE 4.46Å; I542-M580 HydrophobicContact CD1-CE 3.43Å; I542-M580 VanDerWaalsContact CD1-CE 3.43Å; I542-M580 HydrophobicContact CD1-SD 4.45Å; I542-M580 HydrophobicContact CG1-CE 3.85Å; I542-M580 HydrophobicContact CG2-CE 3.75Å
543L83.4Confident72.1Confident10 Ų1084 Ų845%0.05243%0.427CS..EExtended strand (participates in β ladder)trans-77106.3169.8-56.8178.4000109I545 M557 L566 I570 A571 V572 R573 W588L543-I545 HydrophobicContact CB-CD1 4.22Å; L543-I545 HydrophobicContact CB-CG1 4.31Å; L543-M557 HydrophobicContact CD2-CB 4.28Å; L543-L566 HydrophobicContact CD1-CD2 4.43Å; L543-I570 HydrophobicContact CD1-CG2 4.15Å; L543-A571 PolarHBondContact N-O 3.34Å; L543-V572 HydrophobicContact CB-CG2 4.46Å; L543-R573 PolarHBondContact O-N 3.29Å; L543-W588 HydrophobicContact CD1-CH2 4.35Å
544L85.1Confident74.6Confident82 Ų8278.9 Ų78.943%0.42940%0.396SS..EExtended strand (participates in β ladder)trans-84.2116.5173.6-83.2158.2000110.1I542 R573I542-L544 PolarHBondContact O-N 3.05Å; L544-R573 WeakPolarHBondContact CA-O 3.14Å; L544-R573 HydrophobicContact CD2-CB 4.3Å; L544-R573 HydrophobicContact CD2-CG 4.45Å
545I88.6Confident76.8Confident0 Ų071.7 Ų71.70%037%0.365CS..EExtended strand (participates in β ladder)trans-125.2135.9-169.8-53.8-176.1000110.6L543 I550 V572 R573 F574 H575 W588L543-I545 HydrophobicContact CB-CD1 4.22Å; L543-I545 HydrophobicContact CB-CG1 4.31Å; I545-I550 HydrophobicContact CG2-CG1 4.41Å; I545-V572 HydrophobicContact CD1-CG1 3.65Å; I545-V572 HydrophobicContact CD1-CG2 4.39Å; I545-V572 HydrophobicContact CG1-CG1 4.18Å; I545-R573 PolarHBondContact N-O 3.08Å; I545-F574 HydrophobicContact CB-CD1 4.22Å; I545-F574 HydrophobicContact CB-CE1 4.38Å; I545-F574 HydrophobicContact CG2-CD1 4.41Å; I545-F574 HydrophobicContact CG2-CE1 4.28Å; I545-F574 CarbonylContact O-C 3.52Å; I545-F574 WeakPolarHBondContact O-CA 3.44Å; I545-H575 PolarHBondContact O-N 2.87Å; I545-W588 HydrophobicContact CD1-CD2 4.28Å; I545-W588 HydrophobicContact CD1-CG 4.22Å; I545-W588 HydrophobicContact CD1-CZ2 4.08Å
546H87.8Confident78.7Confident81 Ų8167.7 Ų67.738%0.37535%0.354SS..  trans-89.3128.4176-71.1-88000111.3D548 S549 I550 S553 H575H546-D548 VanDerWaalsContact C-N 3.33Å; H546-D548 PolarHBondContact O-N 3.12Å; H546-S549 CarbonylContact O-C 3.5Å; H546-S549 PolarHBondContact O-N 3.45Å; H546-I550 WeakPolarHBondContact O-CA 3.33Å; H546-I550 VanDerWaalsContact O-CG1 3.27Å; H546-I550 WeakPolarHBondContact O-CG1 3.42Å; H546-I550 PolarHBondContact O-N 2.92Å; H546-I550 VanDerWaalsContact O-N 3.09Å; H546-S553 PolarHBondContact N-OG 3.04Å; H546-H575 AromaticContact CE1-CD2 3.26Å; H546-H575 PolarHBondContact CE1-CD2 3.33Å; H546-H575 AromaticContact CE1-CG 3.44Å; H546-H575 VanDerWaalsContact CE1-CG 3.44Å; H546-H575 AromaticContact CE1-NE2 3.87Å; H546-H575 AromaticContact ND1-CD2 3.99Å; H546-H575 AromaticContact ND1-CG 3.7Å; H546-H575 AromaticContact NE2-CD2 3.83Å
547R85.1Confident80.6Confident96 Ų9664.9 Ų64.936%0.36233%0.332SS..G310 helixtrans-64.1-34.9178.5-76.9-161.9-177.2-101.81.9113.6S549 I550 F574 E577 E587R547-S549 PolarHBondContact O-N 3.45Å; R547-I550 HydrophobicContact CB-CD1 4.43Å; R547-I550 HydrophobicContact CG-CD1 4.43Å; R547-I550 WeakPolarHBondContact O-CG1 3.33Å; R547-F574 HydrophobicContact CG-CB 4.3Å; R547-F574 HydrophobicContact CG-CD1 3.81Å; R547-F574 HydrophobicContact CG-CE1 4.37Å; R547-F574 HydrophobicContact CG-CG 4.09Å; R547-E577 WeakPolarHBondContact CD-OE1 3.37Å; R547-E577 IonicContact CZ-OE1 3.2Å; R547-E577 IonicContact CZ-OE2 2.95Å; R547-E577 IonicContact NE-OE1 3.39Å; R547-E577 PolarHBondContact NE-OE1 2.83Å; R547-E577 IonicContact NE-OE2 3.89Å; R547-E577 IonicContact NH2-OE1 2.71Å; R547-E577 PolarHBondContact NH2-OE1 3.42Å; R547-E577 IonicContact NH2-OE2 3.94Å; R547-E577 PolarHBondContact NH2-OE2 3.24Å; R547-E577 VanDerWaalsContact NH2-OE2 3.08Å; R547-E587 IonicContact CZ-OE1 3.39Å; R547-E587 VanDerWaalsContact CZ-OE1 3.26Å; R547-E587 IonicContact NH1-OE1 2.69Å; R547-E587 PolarHBondContact NH1-OE1 3.37Å; R547-E587 IonicContact NH2-OE1 3.89Å; R547-E587 PolarHBondContact NH2-OE1 2.9Å; R547-E587 IonicContact NH2-OE2 2.97Å
548D83.1Confident82Confident163 Ų16360.9 Ų60.987%0.87231%0.308SS*.G310 helixtrans-72.5-12.9-178.4-54.7-40000113.3H546H546-D548 VanDerWaalsContact C-N 3.33Å; H546-D548 PolarHBondContact O-N 3.12Å
549S85.4Confident83.2Confident50 Ų5059.8 Ų59.835%0.3531%0.308SS..G310 helixtrans-145.640.2-17761.10000112.2H546 R547 F551 R552 S553H546-S549 CarbonylContact O-C 3.5Å; H546-S549 PolarHBondContact O-N 3.45Å; R547-S549 PolarHBondContact O-N 3.45Å; S549-F551 VanDerWaalsContact C-N 3.31Å; S549-F551 PolarHBondContact O-N 3.19Å; S549-R552 PolarHBondContact O-N 3.44Å; S549-S553 VanDerWaalsContact O-CB 3.23Å; S549-S553 WeakPolarHBondContact O-CB 3.41Å; S549-S553 PolarHBondContact O-N 2.81Å
550I87.9Confident84.2Confident13 Ų1358.7 Ų58.77%0.06730%0.301CS..Hα-helixtrans-49.9-48.9-170.9-73.4169.5000112.1I545 H546 R547 S554 F574 I591 L592I545-I550 HydrophobicContact CG2-CG1 4.41Å; H546-I550 WeakPolarHBondContact O-CA 3.33Å; H546-I550 VanDerWaalsContact O-CG1 3.27Å; H546-I550 WeakPolarHBondContact O-CG1 3.42Å; H546-I550 PolarHBondContact O-N 2.92Å; H546-I550 VanDerWaalsContact O-N 3.09Å; R547-I550 HydrophobicContact CB-CD1 4.43Å; R547-I550 HydrophobicContact CG-CD1 4.43Å; R547-I550 WeakPolarHBondContact O-CG1 3.33Å; I550-S554 WeakPolarHBondContact O-CB 3.41Å; I550-S554 PolarHBondContact O-N 3.16Å; I550-S554 PolarHBondContact O-OG 3.47Å; I550-F574 HydrophobicContact CD1-CE1 4.4Å; I550-I591 HydrophobicContact CD1-CB 4.45Å; I550-I591 HydrophobicContact CD1-CD1 4.14Å; I550-I591 HydrophobicContact CD1-CG2 3.56Å; I550-I591 HydrophobicContact CG2-CG2 4.16Å; I550-L592 HydrophobicContact CG2-CD2 3.78Å; I550-L592 HydrophobicContact CG2-CG 4.18Å
551F87.9Confident85.2Confident0 Ų055.8 Ų55.80%028%0.281CS..Hα-helixtrans-61.4-51.8-176.4-169.5-105.4000112.4S549 C555 L592 E595 I596 Y601 L603 Y628 F631S549-F551 VanDerWaalsContact C-N 3.31Å; S549-F551 PolarHBondContact O-N 3.19Å; F551-C555 WeakPolarHBondContact O-CB 3.41Å; F551-C555 PolarHBondContact O-N 3.19Å; F551-L592 HydrophobicContact CD2-CD2 4.32Å; F551-E595 HydrophobicContact CB-CB 4.11Å; F551-E595 HydrophobicContact CD2-CB 3.87Å; F551-E595 HydrophobicContact CG-CB 4.36Å; F551-I596 HydrophobicContact CE2-CG1 3.82Å; F551-Y601 HydrophobicContact CB-CE2 3.8Å; F551-Y601 WeakPolarHBondContact CB-OH 3.16Å; F551-Y601 HydrophobicContact CD1-CD1 4.2Å; F551-Y601 HydrophobicContact CD1-CD2 4.07Å; F551-Y601 AromaticContact CD1-CE1 3.93Å; F551-Y601 HydrophobicContact CD1-CE1 3.93Å; F551-Y601 AromaticContact CD1-CE2 3.78Å; F551-Y601 HydrophobicContact CD1-CE2 3.78Å; F551-Y601 HydrophobicContact CD1-CG 4.29Å; F551-Y601 AromaticContact CD1-CZ 3.73Å; F551-Y601 HydrophobicContact CD2-CE2 4.41Å; F551-Y601 HydrophobicContact CE1-CD1 4.44Å; F551-Y601 HydrophobicContact CE1-CD2 4.33Å; F551-Y601 HydrophobicContact CE1-CE2 4.48Å; F551-Y601 HydrophobicContact CE1-CG 4.32Å; F551-Y601 HydrophobicContact CG-CD2 4.29Å; F551-Y601 AromaticContact CG-CE2 3.74Å; F551-Y601 HydrophobicContact CG-CE2 3.74Å; F551-Y601 AromaticContact CG-CZ 3.92Å; F551-L603 HydrophobicContact CE1-CD1 4.18Å; F551-L603 HydrophobicContact CZ-CD1 3.72Å; F551-Y628 HydrophobicContact CD1-CD1 4.32Å; F551-Y628 HydrophobicContact CD1-CE1 4.3Å; F551-Y628 AromaticContact CE1-CD1 3.46Å; F551-Y628 HydrophobicContact CE1-CD1 3.46Å; F551-Y628 VanDerWaalsContact CE1-CD1 3.46Å; F551-Y628 HydrophobicContact CE1-CD2 4.36Å; F551-Y628 AromaticContact CE1-CE1 3.86Å; F551-Y628 HydrophobicContact CE1-CE1 3.86Å; F551-Y628 AromaticContact CE1-CG 3.75Å; F551-Y628 HydrophobicContact CE1-CG 3.75Å; F551-Y628 HydrophobicContact CZ-CD1 4.12Å; F551-Y628 HydrophobicContact CZ-CG 4.29Å; F551-F631 HydrophobicContact CD2-CE1 4.14Å; F551-F631 AromaticContact CE2-CD1 3.99Å; F551-F631 HydrophobicContact CE2-CD1 3.99Å; F551-F631 AromaticContact CE2-CE1 3.92Å; F551-F631 HydrophobicContact CE2-CE1 3.92Å; F551-F631 HydrophobicContact CZ-CD1 4.03Å; F551-F631 HydrophobicContact CZ-CE1 4.37Å
552R86.7Confident85.8Confident151 Ų15156.3 Ų56.357%0.5729%0.287SS*.Hα-helixtrans-68.7-43.8-179.7-68.8-174.3178.8160.63112.3S549 S554 C555 E556S549-R552 PolarHBondContact O-N 3.44Å; R552-S554 VanDerWaalsContact C-N 3.33Å; R552-S554 PolarHBondContact O-N 3.35Å; R552-C555 PolarHBondContact O-N 3.07Å; R552-E556 PolarHBondContact O-N 2.86Å
553S89.3Confident86Confident11 Ų1159 Ų598%0.07730%0.301CS..Hα-helixtrans-61.8-42.1178179.80000111.1H546 S549 E556 M557H546-S553 PolarHBondContact N-OG 3.04Å; S549-S553 VanDerWaalsContact O-CB 3.23Å; S549-S553 WeakPolarHBondContact O-CB 3.41Å; S549-S553 PolarHBondContact O-N 2.81Å; S553-E556 PolarHBondContact O-N 3.38Å; S553-M557 WeakPolarHBondContact O-CB 3.47Å; S553-M557 VanDerWaalsContact O-CG 3.24Å; S553-M557 WeakPolarHBondContact O-CG 3.47Å; S553-M557 PolarHBondContact O-N 3.46Å
554S89.6Confident85.8Confident0 Ų065.6 Ų65.60%033%0.331CS..Hα-helixtrans-66.6-42.6175.7-57.60000111.8I550 R552 E556 M557 V558 W588I550-S554 WeakPolarHBondContact O-CB 3.41Å; I550-S554 PolarHBondContact O-N 3.16Å; I550-S554 PolarHBondContact O-OG 3.47Å; R552-S554 VanDerWaalsContact C-N 3.33Å; R552-S554 PolarHBondContact O-N 3.35Å; S554-E556 VanDerWaalsContact C-N 3.32Å; S554-E556 PolarHBondContact O-N 2.9Å; S554-M557 PolarHBondContact O-N 2.9Å; S554-V558 WeakPolarHBondContact O-CB 3.47Å; S554-V558 VanDerWaalsContact O-CG2 3.27Å; S554-V558 WeakPolarHBondContact O-CG2 3.33Å; S554-V558 PolarHBondContact O-N 3.02Å; S554-W588 PolarHBondContact OG-NE1 3.01Å
555C89Confident85.5Confident22 Ų2266.5 Ų66.515%0.14933%0.332CS..Hα-helixtrans-58.5-43.1176.2-173.40000112.1F551 R552 S559 Y628 F631F551-C555 WeakPolarHBondContact O-CB 3.41Å; F551-C555 PolarHBondContact O-N 3.19Å; R552-C555 PolarHBondContact O-N 3.07Å; C555-S559 VanDerWaalsContact O-CB 3.28Å; C555-S559 WeakPolarHBondContact O-CB 3.26Å; C555-S559 PolarHBondContact O-N 3.22Å; C555-S559 VanDerWaalsContact O-N 3.14Å; C555-S559 PolarHBondContact O-OG 3.39Å; C555-Y628 HydrophobicContact CB-CE1 4.43Å; C555-F631 VanDerWaalsContact CA-CE2 3.48Å; C555-F631 HydrophobicContact CB-CD1 3.9Å; C555-F631 HydrophobicContact CB-CD2 4.09Å; C555-F631 HydrophobicContact CB-CE1 4.02Å; C555-F631 HydrophobicContact CB-CE2 4.21Å; C555-F631 HydrophobicContact CB-CG 3.93Å; C555-F631 HydrophobicContact CB-CZ 4.18Å
556E87Confident85.2Confident105 Ų10566.8 Ų66.849%0.49133%0.334SS..Hα-helixtrans-68.7-41.6178.2-172.9179.4178.700112.3R552 S553 S554 S559 K560R552-E556 PolarHBondContact O-N 2.86Å; S553-E556 PolarHBondContact O-N 3.38Å; S554-E556 VanDerWaalsContact C-N 3.32Å; S554-E556 PolarHBondContact O-N 2.9Å; E556-S559 PolarHBondContact O-OG 2.88Å; E556-K560 HydrophobicContact CG-CD 4.28Å; E556-K560 VanDerWaalsContact O-CG 3.25Å; E556-K560 WeakPolarHBondContact O-CG 3.43Å; E556-K560 PolarHBondContact O-N 2.62Å; E556-K560 WeakPolarHBondContact OE1-CE 3.26Å; E556-K560 IonicContact OE1-NZ 3.08Å; E556-K560 PolarHBondContact OE1-NZ 3.38Å
557M86.2Confident85Confident50 Ų5066 Ų6625%0.24633%0.329CS..Hα-helixtrans-74.7-37-177.5-68-59.1-70.800113.1L543 S553 S554 S561L543-M557 HydrophobicContact CD2-CB 4.28Å; S553-M557 WeakPolarHBondContact O-CB 3.47Å; S553-M557 VanDerWaalsContact O-CG 3.24Å; S553-M557 WeakPolarHBondContact O-CG 3.47Å; S553-M557 PolarHBondContact O-N 3.46Å; S554-M557 PolarHBondContact O-N 2.9Å; M557-S561 PolarHBondContact O-N 3.03Å; M557-S561 PolarHBondContact O-OG 3.38Å
558V86.1Confident84.6Confident5 Ų566.2 Ų66.23%0.0333%0.334CS..Hα-helixtrans-69.1-41.8175.9171.50000110.6S554 K560 S561 L566 W588 F631 I635S554-V558 WeakPolarHBondContact O-CB 3.47Å; S554-V558 VanDerWaalsContact O-CG2 3.27Å; S554-V558 WeakPolarHBondContact O-CG2 3.33Å; S554-V558 PolarHBondContact O-N 3.02Å; V558-K560 VanDerWaalsContact C-N 3.31Å; V558-K560 PolarHBondContact O-N 3.19Å; V558-S561 PolarHBondContact O-N 3.4Å; V558-S561 VanDerWaalsContact O-N 3.15Å; V558-L566 HydrophobicContact CG1-CD1 4.05Å; V558-W588 HydrophobicContact CG2-CH2 4.19Å; V558-W588 HydrophobicContact CG2-CZ2 4.22Å; V558-F631 HydrophobicContact CB-CD2 4.44Å; V558-F631 HydrophobicContact CB-CE2 3.92Å; V558-F631 HydrophobicContact CG1-CD2 4.46Å; V558-F631 HydrophobicContact CG1-CE2 4.24Å; V558-F631 HydrophobicContact CG2-CE2 4.03Å; V558-I635 HydrophobicContact CG2-CD1 4.33Å
559S84.5Confident84.2Confident79 Ų7960.3 Ų60.355%0.55231%0.312SS*.Hα-helixtrans-67.1-28.2177.5580000114C555 E556 S561C555-S559 VanDerWaalsContact O-CB 3.28Å; C555-S559 WeakPolarHBondContact O-CB 3.26Å; C555-S559 PolarHBondContact O-N 3.22Å; C555-S559 VanDerWaalsContact O-N 3.14Å; C555-S559 PolarHBondContact O-OG 3.39Å; E556-S559 PolarHBondContact O-OG 2.88Å; S559-S561 VanDerWaalsContact C-N 3.35Å
560K83.8Confident84Confident137 Ų13758.8 Ų58.860%0.59630%0.3SS*.Hα-helixtrans-76.7-18.6173.2-74.5174-174.2173.60113.8E556 V558E556-K560 HydrophobicContact CG-CD 4.28Å; E556-K560 VanDerWaalsContact O-CG 3.25Å; E556-K560 WeakPolarHBondContact O-CG 3.43Å; E556-K560 PolarHBondContact O-N 2.62Å; E556-K560 WeakPolarHBondContact OE1-CE 3.26Å; E556-K560 IonicContact OE1-NZ 3.08Å; E556-K560 PolarHBondContact OE1-NZ 3.38Å; V558-K560 VanDerWaalsContact C-N 3.31Å; V558-K560 PolarHBondContact O-N 3.19Å
561S82.9Confident83.7Confident36 Ų3659 Ų5925%0.25230%0.304SS..SBendtrans-88.2151.1-177-62.90000111.4M557 V558 S559M557-S561 PolarHBondContact O-N 3.03Å; M557-S561 PolarHBondContact O-OG 3.38Å; V558-S561 PolarHBondContact O-N 3.4Å; V558-S561 VanDerWaalsContact O-N 3.15Å; S559-S561 VanDerWaalsContact C-N 3.35Å
562T83.5Confident83.5Confident77 Ų7759.1 Ų59.147%0.47230%0.304SS..  trans-82.9143.7174.859.70000111.1E564 K565 L566T562-E564 PolarHBondContact O-N 3.39Å; T562-K565 WeakPolarHBondContact O-CB 3.44Å; T562-K565 PolarHBondContact O-N 3.3Å; T562-K565 VanDerWaalsContact OG1-CG 3.27Å; T562-K565 WeakPolarHBondContact OG1-CG 3.35Å; T562-L566 PolarHBondContact O-N 2.98Å
563N83.4Confident83.5Confident72 Ų7255 Ų5539%0.38529%0.289SS..Hα-helixtrans-57.5-35.3-179.4-62.7-26000112.8L566 K567 T754N563-L566 PolarHBondContact O-N 3.38Å; N563-K567 WeakPolarHBondContact O-CG 3.43Å; N563-K567 PolarHBondContact O-N 2.84Å; N563-T754 HydrophobicContact CB-CG2 4.34Å; N563-T754 VanDerWaalsContact CG-CG2 3.49Å; N563-T754 VanDerWaalsContact ND2-CG2 3.29Å; N563-T754 WeakPolarHBondContact ND2-CG2 3.46Å
564E78.8Confident83.4Confident147 Ų14754.5 Ų54.569%0.68729%0.285SS*.Hα-helixtrans-64.6-37.8177.2-66.1173.2175.300112.4T562 K567 Q568T562-E564 PolarHBondContact O-N 3.39Å; E564-K567 PolarHBondContact O-N 3.3Å; E564-Q568 WeakPolarHBondContact O-CG 3.37Å; E564-Q568 PolarHBondContact O-N 3Å
565K79.9Confident83.2Confident101 Ų10160.1 Ų60.144%0.43931%0.311SS..Hα-helixtrans-66.9-46.5175.6-76.7-178.5171.2-141.50111.1D541 T562 K567 Q568 G569D541-K565 IonicContact OD1-NZ 3.12Å; D541-K565 PolarHBondContact OD1-NZ 3.27Å; T562-K565 WeakPolarHBondContact O-CB 3.44Å; T562-K565 PolarHBondContact O-N 3.3Å; T562-K565 VanDerWaalsContact OG1-CG 3.27Å; T562-K565 WeakPolarHBondContact OG1-CG 3.35Å; K565-K567 PolarHBondContact O-N 2.93Å; K565-Q568 PolarHBondContact O-N 3.02Å; K565-G569 PolarHBondContact O-N 3.45Å
566L82.1Confident82.7Confident7 Ų762.9 Ų62.94%0.03734%0.344CS..Hα-helixtrans-62-30.9178.3-65.8173.8000112.3L543 V558 T562 N563 L638 H642 F755L543-L566 HydrophobicContact CD1-CD2 4.43Å; V558-L566 HydrophobicContact CG1-CD1 4.05Å; T562-L566 PolarHBondContact O-N 2.98Å; N563-L566 PolarHBondContact O-N 3.38Å; L566-L638 HydrophobicContact CB-CD1 4.05Å; L566-H642 PolarHBondContact O-CE1 3.4Å; L566-H642 PolarHBondContact O-NE2 3.06Å; L566-F755 HydrophobicContact CB-CE1 4.05Å; L566-F755 HydrophobicContact CB-CZ 4.33Å; L566-F755 HydrophobicContact CD1-CZ 3.98Å
567K82.5Confident82.6Confident64 Ų6461.4 Ų61.428%0.27834%0.337SS..Hα-helixtrans-72.4-31.1173.3-73.8178.4-178.4-175.30113.5N563 E564 K565 G569 Y641 T754 F755N563-K567 WeakPolarHBondContact O-CG 3.43Å; N563-K567 PolarHBondContact O-N 2.84Å; E564-K567 PolarHBondContact O-N 3.3Å; K565-K567 PolarHBondContact O-N 2.93Å; K567-G569 VanDerWaalsContact C-N 3.34Å; K567-Y641 HydrophobicContact CB-CE1 3.92Å; K567-Y641 HydrophobicContact CD-CE2 4.36Å; K567-Y641 HydrophobicContact CG-CE1 4.02Å; K567-Y641 HydrophobicContact CG-CE2 4.18Å; K567-Y641 WeakPolarHBondContact O-CE1 3.39Å; K567-T754 PolarHBondContact NZ-O 2.88Å; K567-F755 HydrophobicContact CG-CD1 4.03Å; K567-F755 HydrophobicContact CG-CE1 4.29Å
568Q76.2Confident81.8Confident100 Ų10068.4 Ų68.447%0.46737%0.369SS..Hα-helixtrans-74.3-22.8179.6-73.4177.429.700113.7E564 K565E564-Q568 WeakPolarHBondContact O-CG 3.37Å; E564-Q568 PolarHBondContact O-N 3Å; K565-Q568 PolarHBondContact O-N 3.02Å
569G75.9Confident81Confident40 Ų4070 Ų7041%0.41239%0.386SS..  trans154.2153.8177.800000112.5K565 K567K565-G569 PolarHBondContact O-N 3.45Å; K567-G569 VanDerWaalsContact C-N 3.34Å
570I80.3Confident80.2Confident17 Ų1770.4 Ų70.49%0.08738%0.38CS..  trans-114.3128.9-178.9-56.1169000109.1L543 V572 V585 W588 F589 L638 H642L543-I570 HydrophobicContact CD1-CG2 4.15Å; I570-V572 HydrophobicContact CG2-CG2 3.88Å; I570-V585 HydrophobicContact CB-CG1 4.34Å; I570-V585 HydrophobicContact CG2-CG1 4.24Å; I570-V585 WeakPolarHBondContact O-CG2 3.22Å; I570-W588 HydrophobicContact CG2-CZ3 4.13Å; I570-F589 HydrophobicContact CD1-CE2 3.92Å; I570-F589 HydrophobicContact CD1-CZ 3.7Å; I570-L638 HydrophobicContact CD1-CD1 3.99Å; I570-L638 HydrophobicContact CD1-CD2 3.51Å; I570-L638 HydrophobicContact CD1-CG 3.61Å; I570-L638 HydrophobicContact CG1-CD2 4.38Å; I570-H642 WeakPolarHBondContact CD1-CD2 3.44Å
571A82.5Confident79.4Confident18 Ų1865.8 Ų65.815%0.14937%0.372CS..EExtended strand (participates in β ladder)trans-124.2121.5169.200000108.9V537 I542 L543V537-A571 HydrophobicContact CG1-CB 3.75Å; I542-A571 HydrophobicContact CG1-CB 4.38Å; L543-A571 PolarHBondContact N-O 3.34Å
572V83.8Confident78.8Confident2 Ų268.7 Ų68.71%0.01238%0.382CS..EExtended strand (participates in β ladder)trans-112.7140.8179.1179.80000109.5L543 I545 I570 V584 V585 W588L543-V572 HydrophobicContact CB-CG2 4.46Å; I545-V572 HydrophobicContact CD1-CG1 3.65Å; I545-V572 HydrophobicContact CD1-CG2 4.39Å; I545-V572 HydrophobicContact CG1-CG1 4.18Å; I570-V572 HydrophobicContact CG2-CG2 3.88Å; V572-V584 HydrophobicContact CB-CG1 4.31Å; V572-V584 HydrophobicContact CG1-CG1 4.28Å; V572-V585 HydrophobicContact CG2-CG2 4.35Å; V572-W588 HydrophobicContact CG1-CB 4.16Å; V572-W588 HydrophobicContact CG1-CG 4.09Å; V572-W588 HydrophobicContact CG2-CB 4.24Å; V572-W588 HydrophobicContact CG2-CD2 3.78Å; V572-W588 HydrophobicContact CG2-CE3 3.82Å; V572-W588 HydrophobicContact CG2-CG 3.99Å; V572-W588 HydrophobicContact CG2-CZ3 4.43Å
573R86.4Confident78.3Confident65 Ų6567 Ų6725%0.24538%0.379CS..EExtended strand (participates in β ladder)trans-134.5127.3168.5-171.3-172.2-70.1157.5-3.8109.3I542 L543 L544 I545 M580I542-R573 HydrophobicContact CG2-CB 3.62Å; L543-R573 PolarHBondContact O-N 3.29Å; L544-R573 WeakPolarHBondContact CA-O 3.14Å; L544-R573 HydrophobicContact CD2-CB 4.3Å; L544-R573 HydrophobicContact CD2-CG 4.45Å; I545-R573 PolarHBondContact N-O 3.08Å; R573-M580 HydrophobicContact CB-CE 4.03Å; R573-M580 HydrophobicContact CG-CE 4.45Å; R573-M580 PolarHBondContact NE-SD 2.73Å; R573-M580 VanDerWaalsContact NE-SD 3.41Å; R573-M580 PolarHBondContact NH2-SD 3.33Å
574F87.3Confident78.3Confident1 Ų164.5 Ų64.50%0.00437%0.367CS..EExtended strand (participates in β ladder)trans-77.2139.3172.1-66.6-65.5000110.7I545 R547 I550 G576 E577 V584 W588 I591I545-F574 HydrophobicContact CB-CD1 4.22Å; I545-F574 HydrophobicContact CB-CE1 4.38Å; I545-F574 HydrophobicContact CG2-CD1 4.41Å; I545-F574 HydrophobicContact CG2-CE1 4.28Å; I545-F574 CarbonylContact O-C 3.52Å; I545-F574 WeakPolarHBondContact O-CA 3.44Å; R547-F574 HydrophobicContact CG-CB 4.3Å; R547-F574 HydrophobicContact CG-CD1 3.81Å; R547-F574 HydrophobicContact CG-CE1 4.37Å; R547-F574 HydrophobicContact CG-CG 4.09Å; I550-F574 HydrophobicContact CD1-CE1 4.4Å; F574-G576 PolarHBondContact O-N 3.12Å; F574-E577 HydrophobicContact CB-CB 4.28Å; F574-E577 HydrophobicContact CB-CG 4.29Å; F574-E577 PolarHBondContact O-N 2.68Å; F574-E577 VanDerWaalsContact O-N 3.1Å; F574-V584 HydrophobicContact CD2-CG1 3.86Å; F574-V584 HydrophobicContact CE2-CG1 3.69Å; F574-W588 HydrophobicContact CZ-CB 4.29Å; F574-I591 HydrophobicContact CZ-CD1 4.34Å
575H85Confident78.5Confident118 Ų11857.8 Ų57.855%0.54634%0.335SS..THydrogen-bonded Turntrans-60.9122.1-177.8-175.1-73.2000111I545 H546I545-H575 PolarHBondContact O-N 2.87Å; H546-H575 AromaticContact CE1-CD2 3.26Å; H546-H575 PolarHBondContact CE1-CD2 3.33Å; H546-H575 AromaticContact CE1-CG 3.44Å; H546-H575 VanDerWaalsContact CE1-CG 3.44Å; H546-H575 AromaticContact CE1-NE2 3.87Å; H546-H575 AromaticContact ND1-CD2 3.99Å; H546-H575 AromaticContact ND1-CG 3.7Å; H546-H575 AromaticContact NE2-CD2 3.83Å
576G79.3Confident78.6Confident80 Ų8060.3 Ų60.383%0.82534%0.342SS*.THydrogen-bonded Turntrans87.63.1-179.300000115.1F574F574-G576 PolarHBondContact O-N 3.12Å
577E84.3Confident78.8Confident74 Ų7463.3 Ų63.335%0.34636%0.356SS..  trans-111.5139.4177-66.4175.9-157.400111.2R547 F574 G579R547-E577 WeakPolarHBondContact CD-OE1 3.37Å; R547-E577 IonicContact CZ-OE1 3.2Å; R547-E577 IonicContact CZ-OE2 2.95Å; R547-E577 IonicContact NE-OE1 3.39Å; R547-E577 PolarHBondContact NE-OE1 2.83Å; R547-E577 IonicContact NE-OE2 3.89Å; R547-E577 IonicContact NH2-OE1 2.71Å; R547-E577 PolarHBondContact NH2-OE1 3.42Å; R547-E577 IonicContact NH2-OE2 3.94Å; R547-E577 PolarHBondContact NH2-OE2 3.24Å; R547-E577 VanDerWaalsContact NH2-OE2 3.08Å; F574-E577 HydrophobicContact CB-CB 4.28Å; F574-E577 HydrophobicContact CB-CG 4.29Å; F574-E577 PolarHBondContact O-N 2.68Å; F574-E577 VanDerWaalsContact O-N 3.1Å; E577-G579 VanDerWaalsContact C-N 3.34Å
578E70.1Confident79.1Confident196 Ų19660.3 Ų60.392%0.91634%0.343SS*.  trans-86.1-7.1176.6-65.7-171.3164.300113M580E578-M580 PolarHBondContact O-N 3.18Å
579G68.3Low79.7Confident39 Ų3955.6 Ų55.640%0.40232%0.321SS..  trans-68.2128.6-178.300000112.5E577E577-G579 VanDerWaalsContact C-N 3.34Å
580M67.4Low80.2Confident87 Ų8757.2 Ų57.243%0.42932%0.32SS..  trans-140.3148.4173.9-54.7-163.687.700110.9I542 R573 E578I542-M580 HydrophobicContact CB-CE 4.46Å; I542-M580 HydrophobicContact CD1-CE 3.43Å; I542-M580 VanDerWaalsContact CD1-CE 3.43Å; I542-M580 HydrophobicContact CD1-SD 4.45Å; I542-M580 HydrophobicContact CG1-CE 3.85Å; I542-M580 HydrophobicContact CG2-CE 3.75Å; R573-M580 HydrophobicContact CB-CE 4.03Å; R573-M580 HydrophobicContact CG-CE 4.45Å; R573-M580 PolarHBondContact NE-SD 2.73Å; R573-M580 VanDerWaalsContact NE-SD 3.41Å; R573-M580 PolarHBondContact NH2-SD 3.33Å; E578-M580 PolarHBondContact O-N 3.18Å
581G68.4Low80.7Confident41 Ų4158.1 Ų58.142%0.42333%0.325SS..SBendtrans135.9-175.3172.500000113.6G583 V584 V585G581-G583 PolarHBondContact O-N 3.04Å; G581-V584 PolarHBondContact O-N 3.24Å; G581-V585 PolarHBondContact O-N 3.01Å
582Q68.9Low81.1Confident97 Ų9757.3 Ų57.345%0.45332%0.318SS..Hα-helixtrans-63.5-22.8-175.9-67.4-62.8-21.900114R586Q582-R586 WeakPolarHBondContact O-CG 3.38Å; Q582-R586 PolarHBondContact O-N 2.89Å; Q582-R586 VanDerWaalsContact O-N 3.16Å; Q582-R586 PolarHBondContact O-NE 3.46Å
583G73.8Confident81.4Confident41 Ų4157.2 Ų57.242%0.42332%0.318SS..Hα-helixtrans-65.6-42.6171.900000112.5G581 R586 E587G581-G583 PolarHBondContact O-N 3.04Å; G583-R586 PolarHBondContact O-N 3.21Å; G583-E587 WeakPolarHBondContact O-CB 3.26Å; G583-E587 PolarHBondContact O-N 3.04Å
584V82.5Confident81.5Confident20 Ų2057.7 Ų57.712%0.12133%0.325CS..Hα-helixtrans-69.7-36.3179.9-1760000111.1V572 F574 G581 E587 W588V572-V584 HydrophobicContact CB-CG1 4.31Å; V572-V584 HydrophobicContact CG1-CG1 4.28Å; F574-V584 HydrophobicContact CD2-CG1 3.86Å; F574-V584 HydrophobicContact CE2-CG1 3.69Å; G581-V584 PolarHBondContact O-N 3.24Å; V584-E587 PolarHBondContact O-N 3.5Å; V584-W588 WeakPolarHBondContact O-CB 3.29Å; V584-W588 PolarHBondContact O-N 3.46Å
585V82.9Confident81.7Confident5 Ų560 Ų603%0.0334%0.336CS..Hα-helixtrans-64.7-43.6174.9178.20000111I570 V572 G581 W588 F589I570-V585 HydrophobicContact CB-CG1 4.34Å; I570-V585 HydrophobicContact CG2-CG1 4.24Å; I570-V585 WeakPolarHBondContact O-CG2 3.22Å; V572-V585 HydrophobicContact CG2-CG2 4.35Å; G581-V585 PolarHBondContact O-N 3.01Å; V585-W588 PolarHBondContact O-N 2.99Å; V585-F589 HydrophobicContact CG1-CD2 3.95Å; V585-F589 HydrophobicContact CG1-CE2 3.79Å; V585-F589 VanDerWaalsContact O-CD2 3.3Å; V585-F589 WeakPolarHBondContact O-CD2 3.35Å; V585-F589 PolarHBondContact O-N 2.84Å; V585-F589 VanDerWaalsContact O-N 3.08Å
586R82.3Confident82Confident154 Ų15454.4 Ų54.458%0.58131%0.31SS*.Hα-helixtrans-60.3-47.8173.6-82.4-175.9-69.3158.8-3.5112.2Q582 G583 W588 F589 D590Q582-R586 WeakPolarHBondContact O-CG 3.38Å; Q582-R586 PolarHBondContact O-N 2.89Å; Q582-R586 VanDerWaalsContact O-N 3.16Å; Q582-R586 PolarHBondContact O-NE 3.46Å; G583-R586 PolarHBondContact O-N 3.21Å; R586-W588 VanDerWaalsContact C-N 3.29Å; R586-W588 PolarHBondContact O-N 3.49Å; R586-F589 PolarHBondContact O-N 2.94Å; R586-D590 PolarHBondContact O-N 2.86Å
587E86.3Confident82.5Confident71 Ų7151.5 Ų51.533%0.33228%0.275SS..Hα-helixtrans-57.7-43.5175.7-175.8-172.8169.900111.3R547 G583 V584 F589 D590 I591R547-E587 IonicContact CZ-OE1 3.39Å; R547-E587 VanDerWaalsContact CZ-OE1 3.26Å; R547-E587 IonicContact NH1-OE1 2.69Å; R547-E587 PolarHBondContact NH1-OE1 3.37Å; R547-E587 IonicContact NH2-OE1 3.89Å; R547-E587 PolarHBondContact NH2-OE1 2.9Å; R547-E587 IonicContact NH2-OE2 2.97Å; G583-E587 WeakPolarHBondContact O-CB 3.26Å; G583-E587 PolarHBondContact O-N 3.04Å; V584-E587 PolarHBondContact O-N 3.5Å; E587-F589 PolarHBondContact O-N 2.72Å; E587-D590 PolarHBondContact O-N 3.43Å; E587-I591 HydrophobicContact CG-CD1 3.76Å; E587-I591 HydrophobicContact CG-CG1 4.35Å; E587-I591 VanDerWaalsContact O-CG1 3.3Å; E587-I591 WeakPolarHBondContact O-CG1 3.33Å; E587-I591 PolarHBondContact O-N 2.94Å
588W89.1Confident82.7Confident0 Ų049.9 Ų49.90%027%0.269CS..Hα-helixtrans-61.1-44.8178.5175.463.7000112.9L543 I545 S554 V558 I570 V572 F574 V584 V585 R586 L592 I635L543-W588 HydrophobicContact CD1-CH2 4.35Å; I545-W588 HydrophobicContact CD1-CD2 4.28Å; I545-W588 HydrophobicContact CD1-CG 4.22Å; I545-W588 HydrophobicContact CD1-CZ2 4.08Å; S554-W588 PolarHBondContact OG-NE1 3.01Å; V558-W588 HydrophobicContact CG2-CH2 4.19Å; V558-W588 HydrophobicContact CG2-CZ2 4.22Å; I570-W588 HydrophobicContact CG2-CZ3 4.13Å; V572-W588 HydrophobicContact CG1-CB 4.16Å; V572-W588 HydrophobicContact CG1-CG 4.09Å; V572-W588 HydrophobicContact CG2-CB 4.24Å; V572-W588 HydrophobicContact CG2-CD2 3.78Å; V572-W588 HydrophobicContact CG2-CE3 3.82Å; V572-W588 HydrophobicContact CG2-CG 3.99Å; V572-W588 HydrophobicContact CG2-CZ3 4.43Å; F574-W588 HydrophobicContact CZ-CB 4.29Å; V584-W588 WeakPolarHBondContact O-CB 3.29Å; V584-W588 PolarHBondContact O-N 3.46Å; V585-W588 PolarHBondContact O-N 2.99Å; R586-W588 VanDerWaalsContact C-N 3.29Å; R586-W588 PolarHBondContact O-N 3.49Å; W588-L592 HydrophobicContact CD2-CD1 3.88Å; W588-L592 HydrophobicContact CE3-CD1 4.48Å; W588-L592 HydrophobicContact CG-CD1 4.38Å; W588-L592 HydrophobicContact CH2-CD1 4.09Å; W588-L592 HydrophobicContact CZ2-CD1 3.4Å; W588-L592 VanDerWaalsContact CZ2-CD1 3.4Å; W588-L592 VanDerWaalsContact NE1-CD1 3.32Å; W588-L592 WeakPolarHBondContact O-CB 3.42Å; W588-L592 WeakPolarHBondContact O-CG 3.42Å; W588-L592 PolarHBondContact O-N 3.38Å; W588-I635 HydrophobicContact CH2-CD1 3.77Å; W588-I635 HydrophobicContact CZ2-CD1 4.07Å
589F89.8Confident83.4Confident1 Ų145.5 Ų45.50%0.00426%0.257CS..Hα-helixtrans-64.2-39.2174.9-82.6-67.4000112.6I570 V585 R586 E587 S593 I635 L638 A639 Q644I570-F589 HydrophobicContact CD1-CE2 3.92Å; I570-F589 HydrophobicContact CD1-CZ 3.7Å; V585-F589 HydrophobicContact CG1-CD2 3.95Å; V585-F589 HydrophobicContact CG1-CE2 3.79Å; V585-F589 VanDerWaalsContact O-CD2 3.3Å; V585-F589 WeakPolarHBondContact O-CD2 3.35Å; V585-F589 PolarHBondContact O-N 2.84Å; V585-F589 VanDerWaalsContact O-N 3.08Å; R586-F589 PolarHBondContact O-N 2.94Å; E587-F589 PolarHBondContact O-N 2.72Å; F589-S593 WeakPolarHBondContact O-CB 3.24Å; F589-S593 PolarHBondContact O-N 3.28Å; F589-S593 PolarHBondContact O-OG 3.26Å; F589-I635 HydrophobicContact CD1-CG2 4.1Å; F589-I635 HydrophobicContact CE1-CG2 4.17Å; F589-L638 HydrophobicContact CZ-CD2 4.27Å; F589-L638 HydrophobicContact CZ-CG 4.19Å; F589-A639 HydrophobicContact CD1-CB 3.82Å; F589-A639 HydrophobicContact CE1-CB 3.67Å; F589-A639 HydrophobicContact CZ-CB 4.31Å; F589-Q644 HydrophobicContact CD2-CB 3.99Å; F589-Q644 HydrophobicContact CD2-CG 3.82Å; F589-Q644 HydrophobicContact CE2-CB 4.23Å; F589-Q644 HydrophobicContact CE2-CG 3.79Å; F589-Q644 HydrophobicContact CG-CB 4.38Å
590D86.4Confident84.2Confident75 Ų7550.4 Ų50.440%0.40128%0.275SS..Hα-helixtrans-68-43179-171.645000111.9R586 E587 S593 N594R586-D590 PolarHBondContact O-N 2.86Å; E587-D590 PolarHBondContact O-N 3.43Å; D590-S593 WeakPolarHBondContact O-CB 3.37Å; D590-S593 PolarHBondContact O-N 2.92Å; D590-N594 PolarHBondContact O-N 3.25Å; D590-N594 PolarHBondContact O-ND2 3.06Å
591I89.7Confident85Confident36 Ų3648 Ų4819%0.18526%0.261CS..Hα-helixtrans-65.1-46.5175.2-61.4165.7000110.4I550 F574 E587 S593 N594 E595I550-I591 HydrophobicContact CD1-CB 4.45Å; I550-I591 HydrophobicContact CD1-CD1 4.14Å; I550-I591 HydrophobicContact CD1-CG2 3.56Å; I550-I591 HydrophobicContact CG2-CG2 4.16Å; F574-I591 HydrophobicContact CZ-CD1 4.34Å; E587-I591 HydrophobicContact CG-CD1 3.76Å; E587-I591 HydrophobicContact CG-CG1 4.35Å; E587-I591 VanDerWaalsContact O-CG1 3.3Å; E587-I591 WeakPolarHBondContact O-CG1 3.33Å; E587-I591 PolarHBondContact O-N 2.94Å; I591-S593 PolarHBondContact O-N 3.24Å; I591-N594 PolarHBondContact O-N 3.46Å; I591-N594 VanDerWaalsContact O-N 3.12Å; I591-E595 HydrophobicContact CG2-CG 4.27Å; I591-E595 PolarHBondContact O-N 3.01Å
592L90.4Very high85.9Confident0 Ų047.1 Ų47.10%025%0.25CC..Hα-helixtrans-60.2-34.2176.8-81.6-179.9000112.6I550 F551 W588 N594 E595 I596 F631 I635I550-L592 HydrophobicContact CG2-CD2 3.78Å; I550-L592 HydrophobicContact CG2-CG 4.18Å; F551-L592 HydrophobicContact CD2-CD2 4.32Å; W588-L592 HydrophobicContact CD2-CD1 3.88Å; W588-L592 HydrophobicContact CE3-CD1 4.48Å; W588-L592 HydrophobicContact CG-CD1 4.38Å; W588-L592 HydrophobicContact CH2-CD1 4.09Å; W588-L592 HydrophobicContact CZ2-CD1 3.4Å; W588-L592 VanDerWaalsContact CZ2-CD1 3.4Å; W588-L592 VanDerWaalsContact NE1-CD1 3.32Å; W588-L592 WeakPolarHBondContact O-CB 3.42Å; W588-L592 WeakPolarHBondContact O-CG 3.42Å; W588-L592 PolarHBondContact O-N 3.38Å; L592-N594 VanDerWaalsContact C-N 3.27Å; L592-N594 PolarHBondContact O-N 3.44Å; L592-E595 PolarHBondContact O-N 3.11Å; L592-I596 VanDerWaalsContact O-CG1 3.24Å; L592-I596 WeakPolarHBondContact O-CG1 3.32Å; L592-I596 PolarHBondContact O-N 3.09Å; L592-F631 HydrophobicContact CD1-CZ 4.49Å; L592-F631 HydrophobicContact CD2-CE1 4.42Å; L592-F631 HydrophobicContact CD2-CZ 4.44Å; L592-I635 HydrophobicContact CB-CG2 4.49Å; L592-I635 HydrophobicContact CD1-CD1 3.82Å; L592-I635 HydrophobicContact CD1-CG1 4.18Å; L592-I635 HydrophobicContact CD1-CG2 4.23Å
593S90.3Very high86.9Confident1 Ų142.5 Ų42.51%0.00723%0.228CC..Hα-helixtrans-58-43.3176.4-66.20000111.4F589 D590 I591 I648F589-S593 WeakPolarHBondContact O-CB 3.24Å; F589-S593 PolarHBondContact O-N 3.28Å; F589-S593 PolarHBondContact O-OG 3.26Å; D590-S593 WeakPolarHBondContact O-CB 3.37Å; D590-S593 PolarHBondContact O-N 2.92Å; I591-S593 PolarHBondContact O-N 3.24Å; S593-I648 VanDerWaalsContact CB-CG1 3.48Å; S593-I648 WeakPolarHBondContact O-CD1 3.39Å; S593-I648 WeakPolarHBondContact O-CG1 3.33Å
594N89Confident87.8Confident75 Ų7540.8 Ų40.840%0.40121%0.209SC..Hα-helixtrans-73.2-35.7176.4-65.8-60.4000112.7D590 I591 L592 I597 N598D590-N594 PolarHBondContact O-N 3.25Å; D590-N594 PolarHBondContact O-ND2 3.06Å; I591-N594 PolarHBondContact O-N 3.46Å; I591-N594 VanDerWaalsContact O-N 3.12Å; L592-N594 VanDerWaalsContact C-N 3.27Å; L592-N594 PolarHBondContact O-N 3.44Å; N594-I597 VanDerWaalsContact O-CG1 3.26Å; N594-I597 WeakPolarHBondContact O-CG1 3.5Å; N594-I597 PolarHBondContact O-N 3.16Å; N594-N598 PolarHBondContact O-N 3.44Å
595E90.8Very high88.1Confident49 Ų4942.2 Ų42.223%0.22922%0.218CC..Hα-helixtrans-69.4-33.8178.1-70.3-59.415300113.1F551 I591 L592 I597 N598 Y601F551-E595 HydrophobicContact CB-CB 4.11Å; F551-E595 HydrophobicContact CD2-CB 3.87Å; F551-E595 HydrophobicContact CG-CB 4.36Å; I591-E595 HydrophobicContact CG2-CG 4.27Å; I591-E595 PolarHBondContact O-N 3.01Å; L592-E595 PolarHBondContact O-N 3.11Å; E595-I597 PolarHBondContact O-N 3.46Å; E595-N598 WeakPolarHBondContact O-CB 3.45Å; E595-N598 PolarHBondContact O-N 2.91Å; E595-N598 VanDerWaalsContact O-N 3.14Å; E595-N598 PolarHBondContact OE2-ND2 3.33Å; E595-Y601 WeakPolarHBondContact O-CD2 3.47Å; E595-Y601 WeakPolarHBondContact OE2-CE2 3.31Å
596I91.6Very high88.3Confident0 Ų047.6 Ų47.60%024%0.243CC..Hα-helixtrans-59.5-38.2177.3-74.5164.1000111.3F551 L592 F604 A632 I635 L636 I648F551-I596 HydrophobicContact CE2-CG1 3.82Å; L592-I596 VanDerWaalsContact O-CG1 3.24Å; L592-I596 WeakPolarHBondContact O-CG1 3.32Å; L592-I596 PolarHBondContact O-N 3.09Å; I596-F604 HydrophobicContact CG2-CD2 3.93Å; I596-F604 HydrophobicContact CG2-CE2 3.61Å; I596-F604 HydrophobicContact CG2-CZ 4.49Å; I596-F604 WeakPolarHBondContact O-CD2 3.42Å; I596-A632 HydrophobicContact CD1-CB 4.26Å; I596-A632 HydrophobicContact CG1-CB 4.2Å; I596-A632 HydrophobicContact CG2-CB 3.92Å; I596-I635 HydrophobicContact CD1-CB 4.34Å; I596-I635 HydrophobicContact CD1-CG2 4.09Å; I596-L636 HydrophobicContact CD1-CD1 3.77Å; I596-I648 HydrophobicContact CB-CD1 4.24Å; I596-I648 HydrophobicContact CD1-CD1 4.11Å; I596-I648 HydrophobicContact CG2-CD1 4.3Å
597I90.8Very high88.4Confident20 Ų2040.8 Ų40.810%0.10322%0.219CC..THydrogen-bonded Turntrans-94.36.9-18060.4176.3000113.3N594 E595 P599 F604 F613 I648N594-I597 VanDerWaalsContact O-CG1 3.26Å; N594-I597 WeakPolarHBondContact O-CG1 3.5Å; N594-I597 PolarHBondContact O-N 3.16Å; E595-I597 PolarHBondContact O-N 3.46Å; I597-P599 WeakPolarHBondContact O-CD 3.21Å; I597-F604 HydrophobicContact CG2-CB 4.42Å; I597-F613 HydrophobicContact CB-CD1 3.9Å; I597-F613 HydrophobicContact CB-CE1 3.92Å; I597-F613 HydrophobicContact CB-CG 4.22Å; I597-F613 HydrophobicContact CB-CZ 4.27Å; I597-F613 HydrophobicContact CD1-CD2 4.18Å; I597-F613 HydrophobicContact CD1-CE1 4.19Å; I597-F613 HydrophobicContact CD1-CE2 3.63Å; I597-F613 HydrophobicContact CD1-CZ 3.65Å; I597-F613 HydrophobicContact CG1-CE1 4.46Å; I597-F613 HydrophobicContact CG1-CZ 4.38Å; I597-F613 HydrophobicContact CG2-CB 4.2Å; I597-F613 HydrophobicContact CG2-CD1 4.01Å; I597-F613 HydrophobicContact CG2-CD2 4.13Å; I597-F613 HydrophobicContact CG2-CE1 4.45Å; I597-F613 HydrophobicContact CG2-CG 3.84Å; I597-I648 HydrophobicContact CG2-CG2 3.65Å
598N88.4Confident87.8Confident39 Ų3938.9 Ų38.921%0.20922%0.215CC..  trans-64.7122.8-179.6-177-15.1000110.1N594 E595 D600 Y601N594-N598 PolarHBondContact O-N 3.44Å; E595-N598 WeakPolarHBondContact O-CB 3.45Å; E595-N598 PolarHBondContact O-N 2.91Å; E595-N598 VanDerWaalsContact O-N 3.14Å; E595-N598 PolarHBondContact OE2-ND2 3.33Å; N598-D600 PolarHBondContact O-N 3.17Å; N598-D600 VanDerWaalsContact O-N 3.08Å; N598-D600 WeakPolarHBondContact OD1-CB 3.42Å; N598-D600 PolarHBondContact OD1-N 3.1Å; N598-Y601 HydrophobicContact CB-CD2 3.9Å; N598-Y601 HydrophobicContact CB-CE2 4.19Å; N598-Y601 PolarHBondContact O-N 3.17Å; N598-Y601 VanDerWaalsContact O-N 3.14Å
599P84.7Confident86.8Confident104 Ų10439.1 Ų39.168%0.67522%0.217SC*.G310 helixtrans-54.9-28.2-179.7-27.335.4000114.1I597 Y601 A602I597-P599 WeakPolarHBondContact O-CD 3.21Å; P599-Y601 PolarHBondContact O-N 3.3Å; P599-A602 PolarHBondContact O-N 3.28Å
600D84.1Confident86.1Confident143 Ų14339.8 Ų39.877%0.76522%0.224SC*.G310 helixtrans-63.7-26.3-178.5-70.6-16.4000113.2N598N598-D600 PolarHBondContact O-N 3.17Å; N598-D600 VanDerWaalsContact O-N 3.08Å; N598-D600 WeakPolarHBondContact OD1-CB 3.42Å; N598-D600 PolarHBondContact OD1-N 3.1Å
601Y85.6Confident85.6Confident36 Ų3637.2 Ų37.214%0.14121%0.211CC..G310 helixtrans-86.6-10.4175.9-62.7-58.6000113.4F551 E595 N598 P599 L603 N622F551-Y601 HydrophobicContact CB-CE2 3.8Å; F551-Y601 WeakPolarHBondContact CB-OH 3.16Å; F551-Y601 HydrophobicContact CD1-CD1 4.2Å; F551-Y601 HydrophobicContact CD1-CD2 4.07Å; F551-Y601 AromaticContact CD1-CE1 3.93Å; F551-Y601 HydrophobicContact CD1-CE1 3.93Å; F551-Y601 AromaticContact CD1-CE2 3.78Å; F551-Y601 HydrophobicContact CD1-CE2 3.78Å; F551-Y601 HydrophobicContact CD1-CG 4.29Å; F551-Y601 AromaticContact CD1-CZ 3.73Å; F551-Y601 HydrophobicContact CD2-CE2 4.41Å; F551-Y601 HydrophobicContact CE1-CD1 4.44Å; F551-Y601 HydrophobicContact CE1-CD2 4.33Å; F551-Y601 HydrophobicContact CE1-CE2 4.48Å; F551-Y601 HydrophobicContact CE1-CG 4.32Å; F551-Y601 HydrophobicContact CG-CD2 4.29Å; F551-Y601 AromaticContact CG-CE2 3.74Å; F551-Y601 HydrophobicContact CG-CE2 3.74Å; F551-Y601 AromaticContact CG-CZ 3.92Å; E595-Y601 WeakPolarHBondContact O-CD2 3.47Å; E595-Y601 WeakPolarHBondContact OE2-CE2 3.31Å; N598-Y601 HydrophobicContact CB-CD2 3.9Å; N598-Y601 HydrophobicContact CB-CE2 4.19Å; N598-Y601 PolarHBondContact O-N 3.17Å; N598-Y601 VanDerWaalsContact O-N 3.14Å; P599-Y601 PolarHBondContact O-N 3.3Å; Y601-L603 PolarHBondContact O-N 3.01Å; Y601-L603 VanDerWaalsContact O-N 3.1Å; Y601-N622 PolarHBondContact O-ND2 3.37Å
602A87.6Confident85.5Confident23 Ų2335.6 Ų35.619%0.1920%0.202CC..THydrogen-bonded Turntrans54.123.2-179.100000114.8P599 N616 S619P599-A602 PolarHBondContact O-N 3.28Å; A602-N616 VanDerWaalsContact O-CB 3.28Å; A602-N616 WeakPolarHBondContact O-CB 3.4Å; A602-N616 PolarHBondContact O-ND2 3.15Å; A602-S619 WeakPolarHBondContact O-CA 3.43Å; A602-S619 WeakPolarHBondContact O-CB 3.18Å
603L89.6Confident85.5Confident0 Ų037 Ų370%021%0.208CC..SBendtrans-79.1-52.3-178.6-59175.8000111.5F551 Y601 N616 H625 Y628 F629F551-L603 HydrophobicContact CE1-CD1 4.18Å; F551-L603 HydrophobicContact CZ-CD1 3.72Å; Y601-L603 PolarHBondContact O-N 3.01Å; Y601-L603 VanDerWaalsContact O-N 3.1Å; L603-N616 VanDerWaalsContact O-CB 3.26Å; L603-N616 WeakPolarHBondContact O-CB 3.4Å; L603-N616 PolarHBondContact O-N 3.41Å; L603-H625 HydrophobicContact CD2-CB 4.05Å; L603-Y628 HydrophobicContact CD1-CG 4.48Å; L603-Y628 HydrophobicContact CD2-CD2 4.48Å; L603-F629 HydrophobicContact CB-CZ 4.28Å; L603-F629 HydrophobicContact CD2-CD2 4.28Å; L603-F629 HydrophobicContact CD2-CE2 4.13Å; L603-F629 WeakPolarHBondContact O-CZ 3.3Å
604F92Very high85.5Confident5 Ų538.2 Ų38.22%0.02221%0.214CC..EExtended strand (participates in β ladder)trans-117149.8179.5-65.8-93.8000110.4I596 I597 F613 Q614 P615 F629 A632 F650 F654 F748I596-F604 HydrophobicContact CG2-CD2 3.93Å; I596-F604 HydrophobicContact CG2-CE2 3.61Å; I596-F604 HydrophobicContact CG2-CZ 4.49Å; I596-F604 WeakPolarHBondContact O-CD2 3.42Å; I597-F604 HydrophobicContact CG2-CB 4.42Å; F604-F613 HydrophobicContact CB-CB 4.35Å; F604-Q614 CarbonylContact C-O 3.42Å; F604-Q614 WeakPolarHBondContact CA-O 3.49Å; F604-P615 HydrophobicContact CD1-CG 4.45Å; F604-P615 HydrophobicContact CE1-CG 4.1Å; F604-F629 HydrophobicContact CD2-CE1 4.42Å; F604-F629 HydrophobicContact CE1-CE1 4.06Å; F604-F629 HydrophobicContact CE2-CD1 4.18Å; F604-F629 AromaticContact CE2-CE1 3.85Å; F604-F629 HydrophobicContact CE2-CE1 3.85Å; F604-F629 AromaticContact CZ-CD1 3.97Å; F604-F629 HydrophobicContact CZ-CD1 3.97Å; F604-F629 AromaticContact CZ-CE1 3.65Å; F604-F629 HydrophobicContact CZ-CE1 3.65Å; F604-A632 HydrophobicContact CE2-CB 4.49Å; F604-F650 HydrophobicContact CD1-CD1 4.28Å; F604-F650 AromaticContact CD1-CE1 3.98Å; F604-F650 HydrophobicContact CD1-CE1 3.98Å; F604-F650 HydrophobicContact CE1-CD1 4.07Å; F604-F650 AromaticContact CE1-CE1 3.59Å; F604-F650 HydrophobicContact CE1-CE1 3.59Å; F604-F650 HydrophobicContact CZ-CE1 4.03Å; F604-F654 HydrophobicContact CE1-CE1 4.16Å; F604-F654 HydrophobicContact CE1-CZ 4.15Å; F604-F748 HydrophobicContact CZ-CD2 4.49Å
605T89.5Confident85.7Confident50 Ų5035 Ų3531%0.30720%0.197SC..EExtended strand (participates in β ladder)trans-118.4147.4172.1490000110F613 Q614 N616T605-F613 WeakPolarHBondContact O-CA 3.4Å; T605-Q614 PolarHBondContact N-O 2.8Å; T605-Q614 PolarHBondContact O-N 3.32Å; T605-N616 HydrophobicContact CG2-CB 3.84Å
606Q87.4Confident85.6Confident118 Ų11833.7 Ų33.755%0.55119%0.192SC*.EExtended strand (participates in β ladder)trans-71.7137.9175.3-167.91742700109.6G610 F613Q606-G610 PolarHBondContact NE2-O 3.19Å; Q606-F613 HydrophobicContact CB-CD1 4.36Å; Q606-F613 HydrophobicContact CB-CE1 4.07Å; Q606-F613 HydrophobicContact CG-CE1 4.38Å
607S83.5Confident85.2Confident11 Ų1136.6 Ų36.68%0.07721%0.212CC..  trans-80.9175.2-179.683.80000112D609 G610 T612 S670S607-D609 PolarHBondContact O-N 3.11Å; S607-D609 PolarHBondContact OG-N 3Å; S607-D609 PolarHBondContact OG-OD1 3.25Å; S607-D609 PolarHBondContact OG-OD2 3.29Å; S607-G610 PolarHBondContact O-N 2.95Å; S607-T612 WeakPolarHBondContact CB-O 3.4Å; S607-T612 WeakPolarHBondContact CB-OG1 3.42Å; S607-T612 PolarHBondContact N-O 3.43Å; S607-T612 PolarHBondContact OG-O 2.94Å; S607-T612 PolarHBondContact OG-OG1 2.91Å; S607-S670 WeakPolarHBondContact CB-O 3.24Å
608A74.1Confident84.9Confident31 Ų3138.1 Ų38.126%0.25622%0.22SC..THydrogen-bonded Turntrans-70.3-9.6179.500000113.9G610 S670 P673 G840A608-G610 VanDerWaalsContact C-N 3.34Å; A608-S670 PolarHBondContact N-O 3.2Å; A608-P673 HydrophobicContact CB-CG 3.96Å; A608-G840 WeakPolarHBondContact O-CA 3.37Å
609D68.6Low84.8Confident5 Ų536.2 Ų36.23%0.02721%0.21CC..THydrogen-bonded Turntrans-83.7-11.5173.268.229.7000113.1S607 T611 T612 G839S607-D609 PolarHBondContact O-N 3.11Å; S607-D609 PolarHBondContact OG-N 3Å; S607-D609 PolarHBondContact OG-OD1 3.25Å; S607-D609 PolarHBondContact OG-OD2 3.29Å; D609-T611 PolarHBondContact O-N 3.45Å; D609-T611 PolarHBondContact OD1-N 3.47Å; D609-T611 PolarHBondContact OD1-OG1 3.07Å; D609-T612 PolarHBondContact OD1-N 3.41Å; D609-T612 PolarHBondContact OD1-OG1 2.86Å; D609-T612 VanDerWaalsContact OD1-OG1 3.05Å; D609-T612 WeakPolarHBondContact OD2-CG2 3.37Å; D609-T612 PolarHBondContact OD2-OG1 3.35Å; D609-G839 CarbonylContact O-C 3.59Å; D609-G839 VanDerWaalsContact O-C 3.27Å; D609-G839 WeakPolarHBondContact O-CA 3.38Å
610G73.9Confident84.7Confident15 Ų1534.1 Ų34.116%0.15520%0.198CC..SBendtrans75.43.5177.900000115Q606 S607 A608Q606-G610 PolarHBondContact NE2-O 3.19Å; S607-G610 PolarHBondContact O-N 2.95Å; A608-G610 VanDerWaalsContact C-N 3.34Å
611T76.7Confident84.6Confident20 Ų2032.1 Ų32.112%0.12319%0.191CC..SBendtrans-126.7-25.4-177.763.80000113.8D609 M838D609-T611 PolarHBondContact O-N 3.45Å; D609-T611 PolarHBondContact OD1-N 3.47Å; D609-T611 PolarHBondContact OD1-OG1 3.07Å; T611-M838 HydrophobicContact CG2-CB 3.83Å
612T87.1Confident84.4Confident2 Ų231.9 Ų31.91%0.01219%0.192CC..  trans-105.4158.4-177.765.40000112.6S607 D609 Y649 T651S607-T612 WeakPolarHBondContact CB-O 3.4Å; S607-T612 WeakPolarHBondContact CB-OG1 3.42Å; S607-T612 PolarHBondContact N-O 3.43Å; S607-T612 PolarHBondContact OG-O 2.94Å; S607-T612 PolarHBondContact OG-OG1 2.91Å; D609-T612 PolarHBondContact OD1-N 3.41Å; D609-T612 PolarHBondContact OD1-OG1 2.86Å; D609-T612 VanDerWaalsContact OD1-OG1 3.05Å; D609-T612 WeakPolarHBondContact OD2-CG2 3.37Å; D609-T612 PolarHBondContact OD2-OG1 3.35Å; T612-Y649 CarbonylContact C-O 3.52Å; T612-Y649 VanDerWaalsContact CA-O 3.3Å; T612-Y649 WeakPolarHBondContact CA-O 3.48Å; T612-T651 WeakPolarHBondContact OG1-CG2 3.46Å
613F90.9Very high84.1Confident29 Ų2936.3 Ų36.313%0.12722%0.219CC..EExtended strand (participates in β ladder)trans-122.4149.8-176.8-66.4-92.2000112.2I597 F604 T605 Q606 Y649 F650 T651I597-F613 HydrophobicContact CB-CD1 3.9Å; I597-F613 HydrophobicContact CB-CE1 3.92Å; I597-F613 HydrophobicContact CB-CG 4.22Å; I597-F613 HydrophobicContact CB-CZ 4.27Å; I597-F613 HydrophobicContact CD1-CD2 4.18Å; I597-F613 HydrophobicContact CD1-CE1 4.19Å; I597-F613 HydrophobicContact CD1-CE2 3.63Å; I597-F613 HydrophobicContact CD1-CZ 3.65Å; I597-F613 HydrophobicContact CG1-CE1 4.46Å; I597-F613 HydrophobicContact CG1-CZ 4.38Å; I597-F613 HydrophobicContact CG2-CB 4.2Å; I597-F613 HydrophobicContact CG2-CD1 4.01Å; I597-F613 HydrophobicContact CG2-CD2 4.13Å; I597-F613 HydrophobicContact CG2-CE1 4.45Å; I597-F613 HydrophobicContact CG2-CG 3.84Å; F604-F613 HydrophobicContact CB-CB 4.35Å; T605-F613 WeakPolarHBondContact O-CA 3.4Å; Q606-F613 HydrophobicContact CB-CD1 4.36Å; Q606-F613 HydrophobicContact CB-CE1 4.07Å; Q606-F613 HydrophobicContact CG-CE1 4.38Å; F613-Y649 PolarHBondContact N-O 3.3Å; F613-F650 HydrophobicContact CB-CD1 4.38Å; F613-F650 CarbonylContact O-C 3.59Å; F613-F650 VanDerWaalsContact O-CA 3.23Å; F613-F650 WeakPolarHBondContact O-CA 3.43Å; F613-T651 PolarHBondContact O-N 2.98Å
614Q90.3Very high83.9Confident28 Ų2840.2 Ų40.213%0.13124%0.24CC..EExtended strand (participates in β ladder)trans-136.9156.8176.867.7-174.423.700111.5F604 T605 N616 T651F604-Q614 CarbonylContact C-O 3.42Å; F604-Q614 WeakPolarHBondContact CA-O 3.49Å; T605-Q614 PolarHBondContact N-O 2.8Å; T605-Q614 PolarHBondContact O-N 3.32Å; Q614-N616 PolarHBondContact O-N 3.44Å; Q614-T651 HydrophobicContact CB-CG2 4Å
615P91.9Very high83.7Confident6 Ų641.1 Ų41.14%0.03924%0.244CC..EExtended strand (participates in β ladder)trans-58.1133.8174.8-2535.4000111.7F604 S617 F629 F654 I741F604-P615 HydrophobicContact CD1-CG 4.45Å; F604-P615 HydrophobicContact CE1-CG 4.1Å; P615-S617 PolarHBondContact O-N 2.83Å; P615-F629 HydrophobicContact CB-CE1 4Å; P615-F629 HydrophobicContact CB-CZ 4.05Å; P615-F629 HydrophobicContact CG-CE1 4.47Å; P615-F654 HydrophobicContact CG-CD2 3.49Å; P615-F654 VanDerWaalsContact CG-CD2 3.49Å; P615-F654 HydrophobicContact CG-CE2 3.35Å; P615-F654 HydrophobicContact CG-CG 4.35Å; P615-F654 HydrophobicContact CG-CZ 4.1Å; P615-I741 HydrophobicContact CB-CB 4.3Å; P615-I741 HydrophobicContact CB-CD1 3.96Å; P615-I741 HydrophobicContact CB-CG2 4.27Å; P615-I741 HydrophobicContact CG-CD1 3.97Å
616N88.9Confident83.8Confident22 Ų2241.9 Ų41.912%0.11825%0.246CC..  trans-74.9120.1176-172.34.2000110.1A602 L603 T605 Q614 N618 S619A602-N616 VanDerWaalsContact O-CB 3.28Å; A602-N616 WeakPolarHBondContact O-CB 3.4Å; A602-N616 PolarHBondContact O-ND2 3.15Å; L603-N616 VanDerWaalsContact O-CB 3.26Å; L603-N616 WeakPolarHBondContact O-CB 3.4Å; L603-N616 PolarHBondContact O-N 3.41Å; T605-N616 HydrophobicContact CG2-CB 3.84Å; Q614-N616 PolarHBondContact O-N 3.44Å; N616-N618 PolarHBondContact O-N 3.1Å; N616-N618 PolarHBondContact OD1-N 2.98Å; N616-S619 VanDerWaalsContact O-CB 3.25Å; N616-S619 WeakPolarHBondContact O-CB 3.28Å; N616-S619 PolarHBondContact O-N 3.14Å; N616-S619 VanDerWaalsContact O-N 3.09Å; N616-S619 PolarHBondContact O-OG 3.21Å
617S84.5Confident84.1Confident61 Ų6140.7 Ų40.743%0.42724%0.243SC..THydrogen-bonded Turntrans-57.9-32.6172.752.80000112P615 S619P615-S617 PolarHBondContact O-N 2.83Å; S617-S619 VanDerWaalsContact C-N 3.32Å; S617-S619 PolarHBondContact O-N 3.25Å
618N82.9Confident84.5Confident52 Ų5241.3 Ų41.328%0.27824%0.244SC..THydrogen-bonded Turntrans-92.318.9179.7-67.6-30.9000113.3N616 S620 V621 F703N616-N618 PolarHBondContact O-N 3.1Å; N616-N618 PolarHBondContact OD1-N 2.98Å; N618-S620 PolarHBondContact O-N 3.11Å; N618-S620 VanDerWaalsContact O-N 3.13Å; N618-V621 VanDerWaalsContact O-CG2 3.29Å; N618-V621 WeakPolarHBondContact O-CG2 3.45Å; N618-V621 PolarHBondContact O-N 2.94Å; N618-F703 HydrophobicContact CB-CE1 3.65Å; N618-F703 HydrophobicContact CB-CZ 3.89Å
619S87Confident85.5Confident0 Ų039.9 Ų39.90%023%0.232CC..G310 helixtrans-61.3-20.2179.944.90000114.1A602 N616 S617 V621 N622 H625 Q744A602-S619 WeakPolarHBondContact O-CA 3.43Å; A602-S619 WeakPolarHBondContact O-CB 3.18Å; N616-S619 VanDerWaalsContact O-CB 3.25Å; N616-S619 WeakPolarHBondContact O-CB 3.28Å; N616-S619 PolarHBondContact O-N 3.14Å; N616-S619 VanDerWaalsContact O-N 3.09Å; N616-S619 PolarHBondContact O-OG 3.21Å; S617-S619 VanDerWaalsContact C-N 3.32Å; S617-S619 PolarHBondContact O-N 3.25Å; S619-V621 PolarHBondContact O-N 2.96Å; S619-N622 PolarHBondContact O-N 2.95Å; S619-H625 VanDerWaalsContact O-CB 3.26Å; S619-H625 WeakPolarHBondContact O-CB 3.44Å; S619-H625 PolarHBondContact OG-ND1 3.24Å; S619-H625 VanDerWaalsContact OG-ND1 3.13Å; S619-Q744 WeakPolarHBondContact OG-CG 3.28Å; S619-Q744 PolarHBondContact OG-NE2 3.28Å; S619-Q744 VanDerWaalsContact OG-NE2 3.12Å
620S82.8Confident86.8Confident59 Ų5942 Ų4241%0.41324%0.242SC..G310 helixtrans-62.4-10.2176.756.30000114.6N618 N622 F703N618-S620 PolarHBondContact O-N 3.11Å; N618-S620 VanDerWaalsContact O-N 3.13Å; S620-N622 PolarHBondContact O-N 3.29Å; S620-F703 WeakPolarHBondContact OG-CZ 3.45Å
621V82.8Confident87.8Confident101 Ų10141.4 Ų41.461%0.61224%0.235SC*.G310 helixtrans-53.5-33.9165.8174.90000111.1N618 S619 P623 F703N618-V621 VanDerWaalsContact O-CG2 3.29Å; N618-V621 WeakPolarHBondContact O-CG2 3.45Å; N618-V621 PolarHBondContact O-N 2.94Å; S619-V621 PolarHBondContact O-N 2.96Å; V621-P623 WeakPolarHBondContact O-CD 3.34Å; V621-F703 HydrophobicContact CG2-CD1 4.23Å; V621-F703 HydrophobicContact CG2-CE1 3.23Å; V621-F703 HydrophobicContact CG2-CZ 3.72Å
622N81.2Confident88.6Confident32 Ų3240.5 Ų40.517%0.17123%0.229CC..SBendtrans-92.9113.5170.9-175.6-9.6000109.2Y601 S619 S620 D624 H625Y601-N622 PolarHBondContact O-ND2 3.37Å; S619-N622 PolarHBondContact O-N 2.95Å; S620-N622 PolarHBondContact O-N 3.29Å; N622-D624 PolarHBondContact O-N 3Å; N622-D624 VanDerWaalsContact O-N 3.11Å; N622-D624 PolarHBondContact OD1-N 3.41Å; N622-H625 HydrophobicContact CB-CB 4.26Å; N622-H625 VanDerWaalsContact O-CB 3.26Å; N622-H625 WeakPolarHBondContact O-CB 3.44Å; N622-H625 PolarHBondContact O-CD2 3.44Å; N622-H625 VanDerWaalsContact O-CD2 3.24Å; N622-H625 PolarHBondContact O-N 3.03Å
623P81.2Confident89Confident115 Ų11540.4 Ų40.475%0.74723%0.229SC*.THydrogen-bonded Turntrans-57.9-28.3-178.6-25.635000114V621V621-P623 WeakPolarHBondContact O-CD 3.34Å
624D84.9Confident89.1Confident83 Ų8340.2 Ų40.244%0.44423%0.228SC..THydrogen-bonded Turntrans-93.210.8-179.5-72.5-48.7000113.4N622 L626 N627 Y628N622-D624 PolarHBondContact O-N 3Å; N622-D624 VanDerWaalsContact O-N 3.11Å; N622-D624 PolarHBondContact OD1-N 3.41Å; D624-L626 VanDerWaalsContact C-N 3.3Å; D624-L626 PolarHBondContact O-N 2.91Å; D624-L626 VanDerWaalsContact O-N 3.16Å; D624-N627 WeakPolarHBondContact O-CB 3.35Å; D624-N627 PolarHBondContact O-N 3.41Å; D624-Y628 HydrophobicContact CB-CD2 4.12Å; D624-Y628 HydrophobicContact CB-CE2 3.8Å; D624-Y628 WeakPolarHBondContact O-CD2 3.46Å; D624-Y628 PolarHBondContact O-N 2.93Å; D624-Y628 VanDerWaalsContact O-N 3.12Å
625H88.2Confident89.3Confident23 Ų2338.9 Ų38.911%0.10622%0.222CC..Hα-helixtrans-54.1-40.7-172.373.3123.6000113.9L603 S619 N622 N627 Y628 F629L603-H625 HydrophobicContact CD2-CB 4.05Å; S619-H625 VanDerWaalsContact O-CB 3.26Å; S619-H625 WeakPolarHBondContact O-CB 3.44Å; S619-H625 PolarHBondContact OG-ND1 3.24Å; S619-H625 VanDerWaalsContact OG-ND1 3.13Å; N622-H625 HydrophobicContact CB-CB 4.26Å; N622-H625 VanDerWaalsContact O-CB 3.26Å; N622-H625 WeakPolarHBondContact O-CB 3.44Å; N622-H625 PolarHBondContact O-CD2 3.44Å; N622-H625 VanDerWaalsContact O-CD2 3.24Å; N622-H625 PolarHBondContact O-N 3.03Å; H625-N627 PolarHBondContact O-N 2.98Å; H625-Y628 PolarHBondContact O-N 2.98Å; H625-F629 WeakPolarHBondContact O-CD2 3.44Å; H625-F629 PolarHBondContact O-N 3.44Å
626L92.3Very high89.3Confident66 Ų6638.6 Ų38.635%0.34622%0.22SC..Hα-helixtrans-64.7-40.2179.4-61.1-178000112.4D624 Y628 F629 Q630 P743 Q744 A747D624-L626 VanDerWaalsContact C-N 3.3Å; D624-L626 PolarHBondContact O-N 2.91Å; D624-L626 VanDerWaalsContact O-N 3.16Å; L626-Y628 VanDerWaalsContact C-N 3.28Å; L626-Y628 PolarHBondContact O-N 3.06Å; L626-F629 PolarHBondContact O-N 3.27Å; L626-Q630 PolarHBondContact O-N 3.08Å; L626-P743 HydrophobicContact CD2-CB 3.9Å; L626-Q744 HydrophobicContact CD2-CG 4.49Å; L626-A747 HydrophobicContact CB-CB 4.33Å; L626-A747 HydrophobicContact CD2-CB 4.4Å; L626-A747 WeakPolarHBondContact O-CB 3.25Å
627N91.9Very high89.5Confident93 Ų9337.6 Ų37.650%0.49722%0.215SC..Hα-helixtrans-63.8-39.1175.8-67.6-29000110.6D624 H625 Q630 F631D624-N627 WeakPolarHBondContact O-CB 3.35Å; D624-N627 PolarHBondContact O-N 3.41Å; H625-N627 PolarHBondContact O-N 2.98Å; N627-Q630 PolarHBondContact O-N 2.85Å; N627-F631 WeakPolarHBondContact O-CB 3.39Å; N627-F631 PolarHBondContact O-N 3.04Å
628Y93Very high89.8Confident25 Ų2534.7 Ų34.710%0.09820%0.195CC..Hα-helixtrans-71.1-34.3176.2-67.4-43.3000113.6F551 C555 L603 D624 H625 L626 F631 A632F551-Y628 HydrophobicContact CD1-CD1 4.32Å; F551-Y628 HydrophobicContact CD1-CE1 4.3Å; F551-Y628 AromaticContact CE1-CD1 3.46Å; F551-Y628 HydrophobicContact CE1-CD1 3.46Å; F551-Y628 VanDerWaalsContact CE1-CD1 3.46Å; F551-Y628 HydrophobicContact CE1-CD2 4.36Å; F551-Y628 AromaticContact CE1-CE1 3.86Å; F551-Y628 HydrophobicContact CE1-CE1 3.86Å; F551-Y628 AromaticContact CE1-CG 3.75Å; F551-Y628 HydrophobicContact CE1-CG 3.75Å; F551-Y628 HydrophobicContact CZ-CD1 4.12Å; F551-Y628 HydrophobicContact CZ-CG 4.29Å; C555-Y628 HydrophobicContact CB-CE1 4.43Å; L603-Y628 HydrophobicContact CD1-CG 4.48Å; L603-Y628 HydrophobicContact CD2-CD2 4.48Å; D624-Y628 HydrophobicContact CB-CD2 4.12Å; D624-Y628 HydrophobicContact CB-CE2 3.8Å; D624-Y628 WeakPolarHBondContact O-CD2 3.46Å; D624-Y628 PolarHBondContact O-N 2.93Å; D624-Y628 VanDerWaalsContact O-N 3.12Å; H625-Y628 PolarHBondContact O-N 2.98Å; L626-Y628 VanDerWaalsContact C-N 3.28Å; L626-Y628 PolarHBondContact O-N 3.06Å; Y628-F631 PolarHBondContact O-N 3.34Å; Y628-A632 WeakPolarHBondContact O-CB 3.49Å; Y628-A632 PolarHBondContact O-N 3.27Å
629F95.4Very high90.2Very high0 Ų032.2 Ų32.20%018%0.181CC..Hα-helixtrans-63.4-43.1169.8-86.1-70.9000111.7L603 F604 P615 H625 L626 F631 A632 G633 Q744 A747 F748L603-F629 HydrophobicContact CB-CZ 4.28Å; L603-F629 HydrophobicContact CD2-CD2 4.28Å; L603-F629 HydrophobicContact CD2-CE2 4.13Å; L603-F629 WeakPolarHBondContact O-CZ 3.3Å; F604-F629 HydrophobicContact CD2-CE1 4.42Å; F604-F629 HydrophobicContact CE1-CE1 4.06Å; F604-F629 HydrophobicContact CE2-CD1 4.18Å; F604-F629 AromaticContact CE2-CE1 3.85Å; F604-F629 HydrophobicContact CE2-CE1 3.85Å; F604-F629 AromaticContact CZ-CD1 3.97Å; F604-F629 HydrophobicContact CZ-CD1 3.97Å; F604-F629 AromaticContact CZ-CE1 3.65Å; F604-F629 HydrophobicContact CZ-CE1 3.65Å; P615-F629 HydrophobicContact CB-CE1 4Å; P615-F629 HydrophobicContact CB-CZ 4.05Å; P615-F629 HydrophobicContact CG-CE1 4.47Å; H625-F629 WeakPolarHBondContact O-CD2 3.44Å; H625-F629 PolarHBondContact O-N 3.44Å; L626-F629 PolarHBondContact O-N 3.27Å; F629-F631 VanDerWaalsContact C-N 3.34Å; F629-A632 PolarHBondContact O-N 3.31Å; F629-G633 PolarHBondContact O-N 3Å; F629-Q744 HydrophobicContact CD1-CB 4.25Å; F629-Q744 HydrophobicContact CD2-CB 3.77Å; F629-Q744 HydrophobicContact CD2-CG 3.76Å; F629-Q744 HydrophobicContact CE1-CB 4.09Å; F629-Q744 HydrophobicContact CE2-CB 3.62Å; F629-Q744 HydrophobicContact CE2-CG 3.32Å; F629-Q744 HydrophobicContact CG-CB 4.09Å; F629-Q744 HydrophobicContact CZ-CB 3.75Å; F629-Q744 HydrophobicContact CZ-CG 3.77Å; F629-A747 HydrophobicContact CB-CB 4.04Å; F629-F748 HydrophobicContact CB-CB 4.48Å; F629-F748 WeakPolarHBondContact O-CA 3.08Å
630Q94.8Very high90.4Very high50 Ų5032.3 Ų32.323%0.23418%0.182CC..Hα-helixtrans-61.2-44.2174.2-172.9-179.12.900111.5L626 N627 G633 Q634 A747 G751L626-Q630 PolarHBondContact O-N 3.08Å; N627-Q630 PolarHBondContact O-N 2.85Å; Q630-G633 PolarHBondContact O-N 2.88Å; Q630-Q634 WeakPolarHBondContact O-CG 3.19Å; Q630-Q634 PolarHBondContact O-N 2.86Å; Q630-A747 VanDerWaalsContact CA-O 3.24Å; Q630-A747 WeakPolarHBondContact CA-O 3.37Å; Q630-A747 HydrophobicContact CB-CB 4.47Å; Q630-A747 WeakPolarHBondContact CB-O 3.25Å; Q630-G751 WeakPolarHBondContact O-CA 3.48Å
631F94.7Very high90.7Very high3 Ų330.3 Ų30.31%0.01317%0.165CC..Hα-helixtrans-62-44.4175.2173.8-113.1000112.4F551 C555 V558 L592 N627 Y628 F629 G633 Q634 I635F551-F631 HydrophobicContact CD2-CE1 4.14Å; F551-F631 AromaticContact CE2-CD1 3.99Å; F551-F631 HydrophobicContact CE2-CD1 3.99Å; F551-F631 AromaticContact CE2-CE1 3.92Å; F551-F631 HydrophobicContact CE2-CE1 3.92Å; F551-F631 HydrophobicContact CZ-CD1 4.03Å; F551-F631 HydrophobicContact CZ-CE1 4.37Å; C555-F631 VanDerWaalsContact CA-CE2 3.48Å; C555-F631 HydrophobicContact CB-CD1 3.9Å; C555-F631 HydrophobicContact CB-CD2 4.09Å; C555-F631 HydrophobicContact CB-CE1 4.02Å; C555-F631 HydrophobicContact CB-CE2 4.21Å; C555-F631 HydrophobicContact CB-CG 3.93Å; C555-F631 HydrophobicContact CB-CZ 4.18Å; V558-F631 HydrophobicContact CB-CD2 4.44Å; V558-F631 HydrophobicContact CB-CE2 3.92Å; V558-F631 HydrophobicContact CG1-CD2 4.46Å; V558-F631 HydrophobicContact CG1-CE2 4.24Å; V558-F631 HydrophobicContact CG2-CE2 4.03Å; L592-F631 HydrophobicContact CD1-CZ 4.49Å; L592-F631 HydrophobicContact CD2-CE1 4.42Å; L592-F631 HydrophobicContact CD2-CZ 4.44Å; N627-F631 WeakPolarHBondContact O-CB 3.39Å; N627-F631 PolarHBondContact O-N 3.04Å; Y628-F631 PolarHBondContact O-N 3.34Å; F629-F631 VanDerWaalsContact C-N 3.34Å; F631-G633 VanDerWaalsContact C-N 3.31Å; F631-G633 PolarHBondContact O-N 2.9Å; F631-Q634 WeakPolarHBondContact O-CB 3.47Å; F631-Q634 PolarHBondContact O-N 3.01Å; F631-Q634 VanDerWaalsContact O-N 3.12Å; F631-I635 HydrophobicContact CD1-CG1 4.49Å; F631-I635 HydrophobicContact CD2-CD1 4.48Å; F631-I635 HydrophobicContact CD2-CG1 4.1Å; F631-I635 HydrophobicContact CE1-CG1 3.99Å; F631-I635 HydrophobicContact CE2-CD1 3.59Å; F631-I635 HydrophobicContact CE2-CG1 3.53Å; F631-I635 HydrophobicContact CZ-CD1 3.69Å; F631-I635 HydrophobicContact CZ-CG1 3.47Å; F631-I635 VanDerWaalsContact CZ-CG1 3.47Å; F631-I635 WeakPolarHBondContact O-CG1 3.42Å; F631-I635 PolarHBondContact O-N 3.05Å
632A94.7Very high90.8Very high0 Ų027.7 Ų27.70%015%0.146CC..Hα-helixtrans-57.8-45.3174.600000111I596 F604 Y628 F629 Q634 I635 L636 F748I596-A632 HydrophobicContact CD1-CB 4.26Å; I596-A632 HydrophobicContact CG1-CB 4.2Å; I596-A632 HydrophobicContact CG2-CB 3.92Å; F604-A632 HydrophobicContact CE2-CB 4.49Å; Y628-A632 WeakPolarHBondContact O-CB 3.49Å; Y628-A632 PolarHBondContact O-N 3.27Å; F629-A632 PolarHBondContact O-N 3.31Å; A632-Q634 PolarHBondContact O-N 3.47Å; A632-I635 PolarHBondContact O-N 3.48Å; A632-L636 WeakPolarHBondContact O-CD1 3.35Å; A632-L636 PolarHBondContact O-N 2.8Å; A632-F748 HydrophobicContact CB-CD2 4.25Å; A632-F748 HydrophobicContact CB-CE2 4.27Å
633G94.6Very high91.2Very high0 Ų032.8 Ų32.80%016%0.163CC..Hα-helixtrans-58.6-43.9173.600000112.9F629 Q630 F631 L636 G637 F748 F752F629-G633 PolarHBondContact O-N 3Å; Q630-G633 PolarHBondContact O-N 2.88Å; F631-G633 VanDerWaalsContact C-N 3.31Å; F631-G633 PolarHBondContact O-N 2.9Å; G633-L636 PolarHBondContact O-N 2.71Å; G633-G637 PolarHBondContact O-N 3.28Å; G633-F748 WeakPolarHBondContact CA-O 3.45Å; G633-F752 VanDerWaalsContact O-CA 3.23Å; G633-F752 WeakPolarHBondContact O-CA 3.27Å; G633-F752 PolarHBondContact O-N 2.84Å
634Q93.5Very high91.5Very high26 Ų2629 Ų2912%0.12114%0.136CC..Hα-helixtrans-60.4-45.8175.7-74.4178.3-25.400112Q630 F631 A632 G637 L638 F755Q630-Q634 WeakPolarHBondContact O-CG 3.19Å; Q630-Q634 PolarHBondContact O-N 2.86Å; F631-Q634 WeakPolarHBondContact O-CB 3.47Å; F631-Q634 PolarHBondContact O-N 3.01Å; F631-Q634 VanDerWaalsContact O-N 3.12Å; A632-Q634 PolarHBondContact O-N 3.47Å; Q634-G637 PolarHBondContact O-N 3.05Å; Q634-L638 WeakPolarHBondContact O-CB 3.34Å; Q634-L638 PolarHBondContact O-N 3.45Å; Q634-F755 HydrophobicContact CB-CE2 4.06Å; Q634-F755 HydrophobicContact CG-CE2 4.22Å
635I93.3Very high91.6Very high0 Ų030.1 Ų30.10%014%0.141CC..Hα-helixtrans-63-44.3179.4-68.2-59.1000111.1V558 W588 F589 L592 I596 F631 A632 L638 A639V558-I635 HydrophobicContact CG2-CD1 4.33Å; W588-I635 HydrophobicContact CH2-CD1 3.77Å; W588-I635 HydrophobicContact CZ2-CD1 4.07Å; F589-I635 HydrophobicContact CD1-CG2 4.1Å; F589-I635 HydrophobicContact CE1-CG2 4.17Å; L592-I635 HydrophobicContact CB-CG2 4.49Å; L592-I635 HydrophobicContact CD1-CD1 3.82Å; L592-I635 HydrophobicContact CD1-CG1 4.18Å; L592-I635 HydrophobicContact CD1-CG2 4.23Å; I596-I635 HydrophobicContact CD1-CB 4.34Å; I596-I635 HydrophobicContact CD1-CG2 4.09Å; F631-I635 HydrophobicContact CD1-CG1 4.49Å; F631-I635 HydrophobicContact CD2-CD1 4.48Å; F631-I635 HydrophobicContact CD2-CG1 4.1Å; F631-I635 HydrophobicContact CE1-CG1 3.99Å; F631-I635 HydrophobicContact CE2-CD1 3.59Å; F631-I635 HydrophobicContact CE2-CG1 3.53Å; F631-I635 HydrophobicContact CZ-CD1 3.69Å; F631-I635 HydrophobicContact CZ-CG1 3.47Å; F631-I635 VanDerWaalsContact CZ-CG1 3.47Å; F631-I635 WeakPolarHBondContact O-CG1 3.42Å; F631-I635 PolarHBondContact O-N 3.05Å; A632-I635 PolarHBondContact O-N 3.48Å; I635-L638 PolarHBondContact O-N 2.85Å; I635-A639 WeakPolarHBondContact O-CB 3.2Å; I635-A639 PolarHBondContact O-N 3.3Å
636L93.9Very high91.6Very high0 Ų029.2 Ų29.20%014%0.137CC..Hα-helixtrans-67.8-40.8178-85.282.8000112.3I596 A632 G633 L638 A639 L640 I648 F650 F748 F752 L773I596-L636 HydrophobicContact CD1-CD1 3.77Å; A632-L636 WeakPolarHBondContact O-CD1 3.35Å; A632-L636 PolarHBondContact O-N 2.8Å; G633-L636 PolarHBondContact O-N 2.71Å; L636-L638 VanDerWaalsContact C-N 3.3Å; L636-L638 PolarHBondContact O-N 3.16Å; L636-A639 PolarHBondContact O-N 3.07Å; L636-L640 WeakPolarHBondContact O-CB 3.5Å; L636-L640 PolarHBondContact O-N 3.34Å; L636-I648 HydrophobicContact CD1-CD1 4.15Å; L636-F650 HydrophobicContact CD2-CE2 3.4Å; L636-F650 VanDerWaalsContact CD2-CE2 3.4Å; L636-F650 HydrophobicContact CD2-CZ 3.7Å; L636-F748 HydrophobicContact CB-CZ 4.43Å; L636-F748 HydrophobicContact CD2-CZ 4.1Å; L636-F752 HydrophobicContact CB-CD2 4.2Å; L636-F752 HydrophobicContact CB-CE2 4.36Å; L636-L773 HydrophobicContact CD2-CD1 4.45Å
637G92.3Very high91.2Very high0 Ų028.3 Ų28.30%013%0.132CC..Hα-helixtrans-63.7-37.3174.200000112.4G633 Q634 Y641 I756G633-G637 PolarHBondContact O-N 3.28Å; Q634-G637 PolarHBondContact O-N 3.05Å; G637-Y641 WeakPolarHBondContact O-CB 3.1Å; G637-Y641 PolarHBondContact O-N 3.19Å; G637-I756 WeakPolarHBondContact O-CD1 3.47Å
638L91.1Very high91Very high1 Ų124 Ų241%0.00511%0.109CC..Hα-helixtrans-72.4-40.8177.7-172.467.7000112.1L566 I570 F589 Q634 I635 L636 L640 Y641 H642 F755L566-L638 HydrophobicContact CB-CD1 4.05Å; I570-L638 HydrophobicContact CD1-CD1 3.99Å; I570-L638 HydrophobicContact CD1-CD2 3.51Å; I570-L638 HydrophobicContact CD1-CG 3.61Å; I570-L638 HydrophobicContact CG1-CD2 4.38Å; F589-L638 HydrophobicContact CZ-CD2 4.27Å; F589-L638 HydrophobicContact CZ-CG 4.19Å; Q634-L638 WeakPolarHBondContact O-CB 3.34Å; Q634-L638 PolarHBondContact O-N 3.45Å; I635-L638 PolarHBondContact O-N 2.85Å; L636-L638 VanDerWaalsContact C-N 3.3Å; L636-L638 PolarHBondContact O-N 3.16Å; L638-L640 VanDerWaalsContact C-N 3.32Å; L638-Y641 PolarHBondContact O-N 3.4Å; L638-H642 PolarHBondContact O-CD2 3.23Å; L638-H642 PolarHBondContact O-N 3.06Å; L638-F755 HydrophobicContact CB-CD2 4.28Å; L638-F755 HydrophobicContact CB-CE2 4.32Å; L638-F755 HydrophobicContact CD1-CD1 4Å; L638-F755 HydrophobicContact CD1-CE1 3.79Å; L638-F755 HydrophobicContact CD1-CG 4.49Å; L638-F755 HydrophobicContact CD1-CZ 4.09Å
639A90.8Very high90.9Very high0 Ų024 Ų240%011%0.109CC..Hα-helixtrans-58.8-48.1173.100000110.1F589 I635 L636 Y641 H642 R643 Q644 V646F589-A639 HydrophobicContact CD1-CB 3.82Å; F589-A639 HydrophobicContact CE1-CB 3.67Å; F589-A639 HydrophobicContact CZ-CB 4.31Å; I635-A639 WeakPolarHBondContact O-CB 3.2Å; I635-A639 PolarHBondContact O-N 3.3Å; L636-A639 PolarHBondContact O-N 3.07Å; A639-Y641 PolarHBondContact O-N 2.97Å; A639-H642 CarbonylContact O-C 3.59Å; A639-H642 PolarHBondContact O-N 3.16Å; A639-R643 PolarHBondContact O-N 3.46Å; A639-Q644 CarbonylContact C-O 3.59Å; A639-Q644 HydrophobicContact CB-CB 4.26Å; A639-Q644 PolarHBondContact O-N 3.45Å; A639-V646 HydrophobicContact CB-CG1 3.52Å
640L90.9Very high90.7Very high2 Ų224.1 Ų24.11%0.0111%0.11CC..Hα-helixtrans-59.6-46.7176.5-176.955.1000111.4F519 Y520 L636 L638 H642 R643 F752 I756 I761 L772 L773F519-L640 HydrophobicContact CE1-CD1 4.17Å; F519-L640 HydrophobicContact CE1-CD2 4.31Å; F519-L640 HydrophobicContact CE1-CG 4.13Å; F519-L640 HydrophobicContact CZ-CD2 3.88Å; F519-L640 HydrophobicContact CZ-CG 4.13Å; Y520-L640 HydrophobicContact CE1-CD1 4.47Å; Y520-L640 VanDerWaalsContact CE1-O 3.27Å; Y520-L640 WeakPolarHBondContact CE1-O 3.46Å; Y520-L640 WeakPolarHBondContact OH-CD1 3.32Å; Y520-L640 PolarHBondContact OH-O 3.08Å; L636-L640 WeakPolarHBondContact O-CB 3.5Å; L636-L640 PolarHBondContact O-N 3.34Å; L638-L640 VanDerWaalsContact C-N 3.32Å; L640-H642 VanDerWaalsContact C-N 3.31Å; L640-H642 PolarHBondContact O-N 3.48Å; L640-R643 PolarHBondContact O-N 2.92Å; L640-R643 VanDerWaalsContact O-N 3.13Å; L640-F752 HydrophobicContact CD2-CZ 3.96Å; L640-I756 HydrophobicContact CB-CD1 4.15Å; L640-I756 HydrophobicContact CB-CG1 4.41Å; L640-I756 HydrophobicContact CD2-CD1 4.08Å; L640-I756 HydrophobicContact CD2-CG1 4.05Å; L640-I756 HydrophobicContact CD2-CG2 4.3Å; L640-I756 HydrophobicContact CG-CD1 3.99Å; L640-I756 HydrophobicContact CG-CG1 4.41Å; L640-I761 HydrophobicContact CD2-CD1 3.94Å; L640-L772 HydrophobicContact CD1-CD1 4.03Å; L640-L772 HydrophobicContact CD1-CD2 3.95Å; L640-L772 HydrophobicContact CD1-CG 3.56Å; L640-L772 HydrophobicContact CD2-CD2 4.03Å; L640-L772 HydrophobicContact CD2-CG 4.46Å; L640-L773 HydrophobicContact CB-CD2 4.13Å; L640-L773 HydrophobicContact CD2-CD2 4.39Å
641Y89.4Confident90.5Very high16 Ų1621.9 Ų21.96%0.06310%0.1CC..Hα-helixtrans-56.8-41.4178.9-171.8-87.6000113L523 L524 K567 G637 L638 A639 R643L523-Y641 HydrophobicContact CD1-CD2 3.98Å; L523-Y641 HydrophobicContact CD1-CE2 4.11Å; L523-Y641 HydrophobicContact CD2-CD2 3.71Å; L523-Y641 HydrophobicContact CD2-CE2 4.28Å; L523-Y641 HydrophobicContact CD2-CG 4.36Å; L523-Y641 HydrophobicContact CG-CD2 3.72Å; L523-Y641 HydrophobicContact CG-CE2 3.8Å; L524-Y641 HydrophobicContact CD2-CE1 4.22Å; K567-Y641 HydrophobicContact CB-CE1 3.92Å; K567-Y641 HydrophobicContact CD-CE2 4.36Å; K567-Y641 HydrophobicContact CG-CE1 4.02Å; K567-Y641 HydrophobicContact CG-CE2 4.18Å; K567-Y641 WeakPolarHBondContact O-CE1 3.39Å; G637-Y641 WeakPolarHBondContact O-CB 3.1Å; G637-Y641 PolarHBondContact O-N 3.19Å; L638-Y641 PolarHBondContact O-N 3.4Å; A639-Y641 PolarHBondContact O-N 2.97Å; Y641-R643 VanDerWaalsContact C-N 3.33Å
642H85.8Confident90Very high47 Ų4723 Ų2322%0.21810%0.103CC..THydrogen-bonded Turntrans-91.413.7-179.4-72.6-73000114.2L566 I570 L638 A639 L640 Q644L566-H642 PolarHBondContact O-CE1 3.4Å; L566-H642 PolarHBondContact O-NE2 3.06Å; I570-H642 WeakPolarHBondContact CD1-CD2 3.44Å; L638-H642 PolarHBondContact O-CD2 3.23Å; L638-H642 PolarHBondContact O-N 3.06Å; A639-H642 CarbonylContact O-C 3.59Å; A639-H642 PolarHBondContact O-N 3.16Å; L640-H642 VanDerWaalsContact C-N 3.31Å; L640-H642 PolarHBondContact O-N 3.48Å; H642-Q644 HydrophobicContact CB-CG 4.07Å; H642-Q644 PolarHBondContact O-N 2.61Å; H642-Q644 PolarHBondContact O-NE2 3.05Å; H642-Q644 VanDerWaalsContact O-NE2 3.12Å
643R87.9Confident89.7Confident139 Ų13923.2 Ų23.253%0.52511%0.105SC..THydrogen-bonded Turntrans53.234.8-176.9-55-171.5-179.2-156.59113.1Y520 A639 L640 Y641Y520-R643 HydrophobicContact CD1-CG 3.87Å; Y520-R643 HydrophobicContact CE1-CG 3.52Å; Y520-R643 HydrophobicContact CE2-CG 4.22Å; Y520-R643 HydrophobicContact CG-CG 4.37Å; A639-R643 PolarHBondContact O-N 3.46Å; L640-R643 PolarHBondContact O-N 2.92Å; L640-R643 VanDerWaalsContact O-N 3.13Å; Y641-R643 VanDerWaalsContact C-N 3.33Å
644Q87.6Confident89.6Confident36 Ų3623.3 Ų23.317%0.16811%0.106CC..  trans-92.9130.6174-59-55.6-50.200109.3F589 A639 H642F589-Q644 HydrophobicContact CD2-CB 3.99Å; F589-Q644 HydrophobicContact CD2-CG 3.82Å; F589-Q644 HydrophobicContact CE2-CB 4.23Å; F589-Q644 HydrophobicContact CE2-CG 3.79Å; F589-Q644 HydrophobicContact CG-CB 4.38Å; A639-Q644 CarbonylContact C-O 3.59Å; A639-Q644 HydrophobicContact CB-CB 4.26Å; A639-Q644 PolarHBondContact O-N 3.45Å; H642-Q644 HydrophobicContact CB-CG 4.07Å; H642-Q644 PolarHBondContact O-N 2.61Å; H642-Q644 PolarHBondContact O-NE2 3.05Å; H642-Q644 VanDerWaalsContact O-NE2 3.12Å
645L87.3Confident89.5Confident106 Ų10622 Ų2256%0.55510%0.1SC*.  trans-79.6138.8175.8-56-178.2000109.6L773L645-L773 WeakPolarHBondContact CA-O 3.3Å
646V88.2Confident89.3Confident4 Ų422.9 Ų22.92%0.02410%0.104CC..  trans-107.4140.4174.3-660000110.1A639 I648 L773 S774A639-V646 HydrophobicContact CB-CG1 3.52Å; V646-I648 VanDerWaalsContact C-N 3.27Å; V646-I648 HydrophobicContact CB-CG1 4.47Å; V646-I648 PolarHBondContact O-N 2.64Å; V646-L773 HydrophobicContact CG2-CB 3.98Å; V646-L773 WeakPolarHBondContact CG2-O 3.36Å; V646-L773 PolarHBondContact N-O 3.5Å; V646-S774 WeakPolarHBondContact O-CA 3.12Å
647N84.7Confident89.2Confident46 Ų4624 Ų2425%0.24611%0.108CC..  trans-93.755.8179.3-169.814.5000110.5
648I88.1Confident89.2Confident2 Ų224.2 Ų24.21%0.0111%0.11CC..  trans-133.6129.4179.4-43177.1000109.2S593 I596 I597 L636 V646 F650 S774S593-I648 VanDerWaalsContact CB-CG1 3.48Å; S593-I648 WeakPolarHBondContact O-CD1 3.39Å; S593-I648 WeakPolarHBondContact O-CG1 3.33Å; I596-I648 HydrophobicContact CB-CD1 4.24Å; I596-I648 HydrophobicContact CD1-CD1 4.11Å; I596-I648 HydrophobicContact CG2-CD1 4.3Å; I597-I648 HydrophobicContact CG2-CG2 3.65Å; L636-I648 HydrophobicContact CD1-CD1 4.15Å; V646-I648 VanDerWaalsContact C-N 3.27Å; V646-I648 HydrophobicContact CB-CG1 4.47Å; V646-I648 PolarHBondContact O-N 2.64Å; I648-F650 HydrophobicContact CB-CE2 4.47Å; I648-F650 HydrophobicContact CB-CZ 4.3Å; I648-F650 HydrophobicContact CG2-CD1 4.32Å; I648-F650 HydrophobicContact CG2-CE1 3.72Å; I648-F650 HydrophobicContact CG2-CE2 4.08Å; I648-F650 HydrophobicContact CG2-CZ 3.59Å; I648-S774 PolarHBondContact O-OG 2.8Å
649Y89.8Confident89.1Confident27 Ų2724.6 Ų24.611%0.10611%0.112CC..  trans-117.3119.4179.5-59.3-88000109T612 F613 E770 S826 R828T612-Y649 CarbonylContact C-O 3.52Å; T612-Y649 VanDerWaalsContact CA-O 3.3Å; T612-Y649 WeakPolarHBondContact CA-O 3.48Å; F613-Y649 PolarHBondContact N-O 3.3Å; Y649-E770 HydrophobicContact CD1-CG 4.24Å; Y649-E770 WeakPolarHBondContact CD1-OE1 3.23Å; Y649-S826 VanDerWaalsContact CD1-OG 3.31Å; Y649-S826 WeakPolarHBondContact CD1-OG 3.39Å; Y649-R828 HydrophobicContact CD1-CB 4.22Å; Y649-R828 HydrophobicContact CD2-CB 4.21Å; Y649-R828 HydrophobicContact CD2-CG 4.26Å; Y649-R828 HydrophobicContact CE1-CB 3.85Å; Y649-R828 HydrophobicContact CE1-CG 4.48Å; Y649-R828 HydrophobicContact CE2-CB 3.86Å; Y649-R828 HydrophobicContact CE2-CG 3.66Å; Y649-R828 HydrophobicContact CG-CB 4.38Å
650F91.9Very high88.8Confident2 Ų227.8 Ų27.81%0.00914%0.144CC..BIsolated β-bridgetrans-97.6165.8178.6-57.4-73.5000112.1F604 F613 L636 I648 F654 Y655F604-F650 HydrophobicContact CD1-CD1 4.28Å; F604-F650 AromaticContact CD1-CE1 3.98Å; F604-F650 HydrophobicContact CD1-CE1 3.98Å; F604-F650 HydrophobicContact CE1-CD1 4.07Å; F604-F650 AromaticContact CE1-CE1 3.59Å; F604-F650 HydrophobicContact CE1-CE1 3.59Å; F604-F650 HydrophobicContact CZ-CE1 4.03Å; F613-F650 HydrophobicContact CB-CD1 4.38Å; F613-F650 CarbonylContact O-C 3.59Å; F613-F650 VanDerWaalsContact O-CA 3.23Å; F613-F650 WeakPolarHBondContact O-CA 3.43Å; L636-F650 HydrophobicContact CD2-CE2 3.4Å; L636-F650 VanDerWaalsContact CD2-CE2 3.4Å; L636-F650 HydrophobicContact CD2-CZ 3.7Å; I648-F650 HydrophobicContact CB-CE2 4.47Å; I648-F650 HydrophobicContact CB-CZ 4.3Å; I648-F650 HydrophobicContact CG2-CD1 4.32Å; I648-F650 HydrophobicContact CG2-CE1 3.72Å; I648-F650 HydrophobicContact CG2-CE2 4.08Å; I648-F650 HydrophobicContact CG2-CZ 3.59Å; F650-F654 HydrophobicContact CB-CB 4.13Å; F650-F654 HydrophobicContact CB-CD1 3.66Å; F650-F654 HydrophobicContact CB-CG 4.35Å; F650-F654 AromaticContact CD1-CD1 3.68Å; F650-F654 HydrophobicContact CD1-CD1 3.68Å; F650-F654 AromaticContact CD1-CE1 3.91Å; F650-F654 HydrophobicContact CD1-CE1 3.91Å; F650-F654 AromaticContact CD2-CD1 3.98Å; F650-F654 HydrophobicContact CD2-CD1 3.98Å; F650-F654 HydrophobicContact CD2-CE1 4.23Å; F650-F654 HydrophobicContact CE1-CD1 4.3Å; F650-F654 HydrophobicContact CE1-CE1 4.05Å; F650-F654 HydrophobicContact CE2-CE1 4.37Å; F650-F654 AromaticContact CG-CD1 3.5Å; F650-F654 HydrophobicContact CG-CD1 3.5Å; F650-F654 HydrophobicContact CG-CE1 4.01Å; F650-F654 HydrophobicContact CZ-CE1 4.28Å; F650-Y655 HydrophobicContact CB-CD2 4.37Å; F650-Y655 HydrophobicContact CB-CE1 4.28Å; F650-Y655 HydrophobicContact CB-CE2 3.86Å; F650-Y655 AromaticContact CD2-CE1 3.82Å; F650-Y655 HydrophobicContact CD2-CE1 3.82Å; F650-Y655 AromaticContact CD2-CZ 3.85Å; F650-Y655 PolarHBondContact N-OH 2.85Å; F650-Y655 WeakPolarHBondContact O-CE2 3.42Å
651T89.1Confident88.5Confident3 Ų329.9 Ų29.92%0.01816%0.155CC..  trans-66.4151.4170.257.20000111.1T612 F613 Q614 S653 F654 Y655T612-T651 WeakPolarHBondContact OG1-CG2 3.46Å; F613-T651 PolarHBondContact O-N 2.98Å; Q614-T651 HydrophobicContact CB-CG2 4Å; T651-S653 VanDerWaalsContact C-N 3.25Å; T651-S653 PolarHBondContact O-N 2.86Å; T651-S653 PolarHBondContact OG1-OG 3.38Å; T651-S653 VanDerWaalsContact OG1-OG 3.07Å; T651-F654 WeakPolarHBondContact O-CB 3.46Å; T651-F654 PolarHBondContact O-N 3.41Å; T651-Y655 WeakPolarHBondContact O-CD2 3.37Å; T651-Y655 PolarHBondContact O-N 3.37Å
652R85.5Confident88.2Confident25 Ų2534.4 Ų34.49%0.09419%0.187CC..Hα-helixtrans-54.3-41.7178.7-68.7-71.1170.3-135.9-16.7112.8F654 Y655 K656 E766 E770 G825R652-F654 PolarHBondContact O-N 3.13Å; R652-Y655 PolarHBondContact O-N 3.26Å; R652-K656 WeakPolarHBondContact O-CG 3.45Å; R652-K656 PolarHBondContact O-N 3.26Å; R652-E766 PolarHBondContact NH1-O 3.09Å; R652-E766 VanDerWaalsContact NH1-O 3.08Å; R652-E770 IonicContact CZ-OE2 2.87Å; R652-E770 IonicContact NH1-OE2 2.83Å; R652-E770 PolarHBondContact NH1-OE2 3Å; R652-E770 IonicContact NH2-OE2 3.78Å; R652-E770 PolarHBondContact NH2-OE2 3.4Å; R652-G825 PolarHBondContact NH2-O 2.87Å
653S87.8Confident88.2Confident5 Ų533.4 Ų33.44%0.03518%0.184CC..Hα-helixtrans-56.9-36.6175.146.40000112.9T651 K656 H657 M737T651-S653 VanDerWaalsContact C-N 3.25Å; T651-S653 PolarHBondContact O-N 2.86Å; T651-S653 PolarHBondContact OG1-OG 3.38Å; T651-S653 VanDerWaalsContact OG1-OG 3.07Å; S653-K656 PolarHBondContact O-N 3.47Å; S653-H657 PolarHBondContact O-CD2 2.82Å; S653-H657 PolarHBondContact O-N 3.11Å; S653-M737 WeakPolarHBondContact OG-CE 3.27Å
654F92.1Very high87.9Confident2 Ų228.4 Ų28.41%0.00917%0.17CC..Hα-helixtrans-73.9-39.1179.8-169.1-115.7000111.9F604 P615 F650 T651 R652 K656 H657 I658 I745 F748F604-F654 HydrophobicContact CE1-CE1 4.16Å; F604-F654 HydrophobicContact CE1-CZ 4.15Å; P615-F654 HydrophobicContact CG-CD2 3.49Å; P615-F654 VanDerWaalsContact CG-CD2 3.49Å; P615-F654 HydrophobicContact CG-CE2 3.35Å; P615-F654 HydrophobicContact CG-CG 4.35Å; P615-F654 HydrophobicContact CG-CZ 4.1Å; F650-F654 HydrophobicContact CB-CB 4.13Å; F650-F654 HydrophobicContact CB-CD1 3.66Å; F650-F654 HydrophobicContact CB-CG 4.35Å; F650-F654 AromaticContact CD1-CD1 3.68Å; F650-F654 HydrophobicContact CD1-CD1 3.68Å; F650-F654 AromaticContact CD1-CE1 3.91Å; F650-F654 HydrophobicContact CD1-CE1 3.91Å; F650-F654 AromaticContact CD2-CD1 3.98Å; F650-F654 HydrophobicContact CD2-CD1 3.98Å; F650-F654 HydrophobicContact CD2-CE1 4.23Å; F650-F654 HydrophobicContact CE1-CD1 4.3Å; F650-F654 HydrophobicContact CE1-CE1 4.05Å; F650-F654 HydrophobicContact CE2-CE1 4.37Å; F650-F654 AromaticContact CG-CD1 3.5Å; F650-F654 HydrophobicContact CG-CD1 3.5Å; F650-F654 HydrophobicContact CG-CE1 4.01Å; F650-F654 HydrophobicContact CZ-CE1 4.28Å; T651-F654 WeakPolarHBondContact O-CB 3.46Å; T651-F654 PolarHBondContact O-N 3.41Å; R652-F654 PolarHBondContact O-N 3.13Å; F654-K656 VanDerWaalsContact C-N 3.32Å; F654-K656 PolarHBondContact O-N 3.12Å; F654-H657 WeakPolarHBondContact O-CB 3.24Å; F654-H657 PolarHBondContact O-N 3.14Å; F654-I658 HydrophobicContact CD1-CD1 4.11Å; F654-I658 HydrophobicContact CE1-CD1 3.99Å; F654-I658 WeakPolarHBondContact O-CG1 3.47Å; F654-I658 PolarHBondContact O-N 3.41Å; F654-I745 HydrophobicContact CE2-CG1 4.25Å; F654-F748 HydrophobicContact CE1-CD1 4.47Å; F654-F748 HydrophobicContact CE1-CE1 4.18Å; F654-F748 HydrophobicContact CE1-CE2 4.37Å; F654-F748 HydrophobicContact CE1-CZ 4.12Å; F654-F748 AromaticContact CZ-CD1 3.87Å; F654-F748 HydrophobicContact CZ-CD1 3.87Å; F654-F748 HydrophobicContact CZ-CD2 4.14Å; F654-F748 HydrophobicContact CZ-CE1 4.04Å; F654-F748 HydrophobicContact CZ-CE2 4.28Å; F654-F748 AromaticContact CZ-CG 3.93Å; F654-F748 HydrophobicContact CZ-CG 3.93Å; F654-F748 HydrophobicContact CZ-CZ 4.24Å
655Y92Very high87.6Confident0 Ų029.3 Ų29.30%017%0.172CC..Hα-helixtrans-61.5-40170.5-67.5-61.9000112.1F650 T651 R652 H657 I658 L659 L769 E770 L773F650-Y655 HydrophobicContact CB-CD2 4.37Å; F650-Y655 HydrophobicContact CB-CE1 4.28Å; F650-Y655 HydrophobicContact CB-CE2 3.86Å; F650-Y655 AromaticContact CD2-CE1 3.82Å; F650-Y655 HydrophobicContact CD2-CE1 3.82Å; F650-Y655 AromaticContact CD2-CZ 3.85Å; F650-Y655 PolarHBondContact N-OH 2.85Å; F650-Y655 WeakPolarHBondContact O-CE2 3.42Å; T651-Y655 WeakPolarHBondContact O-CD2 3.37Å; T651-Y655 PolarHBondContact O-N 3.37Å; R652-Y655 PolarHBondContact O-N 3.26Å; Y655-H657 VanDerWaalsContact C-N 3.33Å; Y655-H657 PolarHBondContact O-N 3.38Å; Y655-I658 HydrophobicContact CD1-CD1 4.37Å; Y655-I658 PolarHBondContact O-N 2.63Å; Y655-I658 VanDerWaalsContact O-N 3.16Å; Y655-L659 WeakPolarHBondContact O-CG 3.42Å; Y655-L659 PolarHBondContact O-N 3.48Å; Y655-L769 HydrophobicContact CD1-CB 4.34Å; Y655-L769 HydrophobicContact CD1-CD2 3.86Å; Y655-L769 HydrophobicContact CD1-CG 3.87Å; Y655-L769 HydrophobicContact CE1-CG 4.46Å; Y655-E770 HydrophobicContact CD2-CB 4.44Å; Y655-E770 HydrophobicContact CE1-CB 4.25Å; Y655-E770 HydrophobicContact CE2-CB 3.82Å; Y655-E770 HydrophobicContact CE2-CG 4.09Å; Y655-L773 HydrophobicContact CE1-CD1 4.07Å
656K89.9Confident87.1Confident18 Ų1828.4 Ų28.48%0.07817%0.165CC..Hα-helixtrans-59.2-42.3172.6-73.6178.5179.6171.30112R652 S653 F654 I658 L659 G660 I661 V663 D667 E766R652-K656 WeakPolarHBondContact O-CG 3.45Å; R652-K656 PolarHBondContact O-N 3.26Å; S653-K656 PolarHBondContact O-N 3.47Å; F654-K656 VanDerWaalsContact C-N 3.32Å; F654-K656 PolarHBondContact O-N 3.12Å; K656-I658 VanDerWaalsContact C-N 3.35Å; K656-I658 PolarHBondContact O-N 2.9Å; K656-L659 CarbonylContact O-C 3.54Å; K656-L659 PolarHBondContact O-N 3.32Å; K656-G660 PolarHBondContact O-N 2.86Å; K656-I661 HydrophobicContact CB-CB 4.06Å; K656-I661 HydrophobicContact CB-CG2 4.44Å; K656-I661 HydrophobicContact CD-CG2 4.37Å; K656-I661 HydrophobicContact CG-CB 4.21Å; K656-I661 HydrophobicContact CG-CG2 4.16Å; K656-I661 PolarHBondContact O-N 2.98Å; K656-V663 HydrophobicContact CB-CG1 4.46Å; K656-D667 VanDerWaalsContact NZ-CG 3.26Å; K656-D667 IonicContact NZ-OD1 3.56Å; K656-D667 PolarHBondContact NZ-OD1 2.9Å; K656-D667 IonicContact NZ-OD2 2.67Å; K656-D667 PolarHBondContact NZ-OD2 2.88Å; K656-E766 WeakPolarHBondContact CE-OE1 3.36Å; K656-E766 HydrophobicContact CG-CB 3.99Å; K656-E766 HydrophobicContact CG-CG 4.18Å; K656-E766 IonicContact NZ-OE1 3.55Å
657H91.3Very high86.9Confident22 Ų2229 Ų2910%0.10217%0.168CC..Hα-helixtrans-60.8-40.6173.7-71.1-43.8000112.9S653 F654 Y655 L659 G660 M737 T738 I745S653-H657 PolarHBondContact O-CD2 2.82Å; S653-H657 PolarHBondContact O-N 3.11Å; F654-H657 WeakPolarHBondContact O-CB 3.24Å; F654-H657 PolarHBondContact O-N 3.14Å; Y655-H657 VanDerWaalsContact C-N 3.33Å; Y655-H657 PolarHBondContact O-N 3.38Å; H657-L659 VanDerWaalsContact C-N 3.27Å; H657-L659 PolarHBondContact O-N 3.45Å; H657-G660 PolarHBondContact O-N 3.26Å; H657-M737 PolarHBondContact NE2-O 3.07Å; H657-T738 PolarHBondContact CE1-OG1 3.38Å; H657-I745 HydrophobicContact CB-CD1 4.3Å; H657-I745 HydrophobicContact CB-CG2 4.1Å; H657-I745 VanDerWaalsContact CD2-CD1 3.46Å; H657-I745 WeakPolarHBondContact CD2-CD1 3.46Å
658I92.2Very high86.8Confident6 Ų626.9 Ų26.93%0.03116%0.157CC..Hα-helixtrans-62.7-37.3176.3-63.3167.1000111.3F654 Y655 K656 F748 L749 F752 L769F654-I658 HydrophobicContact CD1-CD1 4.11Å; F654-I658 HydrophobicContact CE1-CD1 3.99Å; F654-I658 WeakPolarHBondContact O-CG1 3.47Å; F654-I658 PolarHBondContact O-N 3.41Å; Y655-I658 HydrophobicContact CD1-CD1 4.37Å; Y655-I658 PolarHBondContact O-N 2.63Å; Y655-I658 VanDerWaalsContact O-N 3.16Å; K656-I658 VanDerWaalsContact C-N 3.35Å; K656-I658 PolarHBondContact O-N 2.9Å; I658-F748 HydrophobicContact CD1-CE1 3.82Å; I658-F748 HydrophobicContact CD1-CZ 4.39Å; I658-F748 HydrophobicContact CG1-CD1 4.47Å; I658-F748 HydrophobicContact CG1-CE1 3.99Å; I658-L749 HydrophobicContact CB-CD2 4.32Å; I658-L749 HydrophobicContact CG1-CD2 4.33Å; I658-L749 HydrophobicContact CG2-CD2 4.27Å; I658-F752 HydrophobicContact CG2-CD1 4.31Å; I658-F752 HydrophobicContact CG2-CE1 4.07Å; I658-F752 HydrophobicContact CG2-CZ 4.48Å; I658-L769 HydrophobicContact CB-CD2 3.88Å; I658-L769 HydrophobicContact CD1-CD2 4.38Å; I658-L769 HydrophobicContact CG2-CD2 3.72Å
659L88.5Confident86.2Confident9 Ų928.8 Ų28.85%0.04717%0.17CC..Hα-helixtrans-82.8-11.4179.9-64.4169.6000113.7Y655 K656 H657 I661 I761 D765 E766 L769Y655-L659 WeakPolarHBondContact O-CG 3.42Å; Y655-L659 PolarHBondContact O-N 3.48Å; K656-L659 CarbonylContact O-C 3.54Å; K656-L659 PolarHBondContact O-N 3.32Å; H657-L659 VanDerWaalsContact C-N 3.27Å; H657-L659 PolarHBondContact O-N 3.45Å; L659-I661 VanDerWaalsContact C-N 3.34Å; L659-I661 HydrophobicContact CB-CD1 3.74Å; L659-I661 HydrophobicContact CB-CG1 3.8Å; L659-I661 HydrophobicContact CD1-CD1 3.76Å; L659-I661 HydrophobicContact CG-CD1 4.4Å; L659-I761 HydrophobicContact CD2-CG1 4.2Å; L659-I761 HydrophobicContact CD2-CG2 4.42Å; L659-I761 VanDerWaalsContact CD2-O 3.25Å; L659-I761 WeakPolarHBondContact CD2-O 3.21Å; L659-D765 WeakPolarHBondContact CD1-O 3.12Å; L659-E766 HydrophobicContact CD1-CB 4.24Å; L659-L769 HydrophobicContact CD1-CB 4.43Å; L659-L769 HydrophobicContact CD1-CD2 4.22Å; L659-L769 HydrophobicContact CD2-CD2 3.95Å; L659-L769 HydrophobicContact CG-CD2 3.8Å
660G85.4Confident85.5Confident66 Ų6628.1 Ų28.168%0.6817%0.169SC*.THydrogen-bonded Turntrans72.525.1-172.500000113.8K656 H657K656-G660 PolarHBondContact O-N 2.86Å; H657-G660 PolarHBondContact O-N 3.26Å
661I84.9Confident84.7Confident47 Ų4730.8 Ų30.824%0.24118%0.183CC..PPolyproline II helixtrans-89.1135.5177.5-60.4172.3000109K656 L659K656-I661 HydrophobicContact CB-CB 4.06Å; K656-I661 HydrophobicContact CB-CG2 4.44Å; K656-I661 HydrophobicContact CD-CG2 4.37Å; K656-I661 HydrophobicContact CG-CB 4.21Å; K656-I661 HydrophobicContact CG-CG2 4.16Å; K656-I661 PolarHBondContact O-N 2.98Å; L659-I661 VanDerWaalsContact C-N 3.34Å; L659-I661 HydrophobicContact CB-CD1 3.74Å; L659-I661 HydrophobicContact CB-CG1 3.8Å; L659-I661 HydrophobicContact CD1-CD1 3.76Å; L659-I661 HydrophobicContact CG-CD1 4.4Å
662P83Confident84.2Confident111 Ų11133.7 Ų33.772%0.72120%0.199SC*.PPolyproline II helixtrans-66.2140.7176.427.6-34.5000112
663V84.6Confident83.8Confident26 Ų2634.4 Ų34.416%0.15821%0.206CC..PPolyproline II helixtrans-78.5149.1176.9-66.70000112K656 T733 M737K656-V663 HydrophobicContact CB-CG1 4.46Å; V663-T733 HydrophobicContact CG2-CG2 4.22Å; V663-M737 HydrophobicContact CG2-CB 4.02Å
664S82.9Confident83.4Confident33 Ų3341 Ų4123%0.23124%0.237CC..  trans-112.1159.4179.4176.70000111.4Q666 D667 T733S664-Q666 PolarHBondContact O-N 2.87Å; S664-Q666 VanDerWaalsContact O-N 3.13Å; S664-D667 PolarHBondContact N-OD2 3.39Å; S664-D667 WeakPolarHBondContact O-CB 3.38Å; S664-D667 PolarHBondContact O-N 3.27Å; S664-T733 WeakPolarHBondContact O-CG2 3.4Å
665Y79.8Confident82.9Confident56 Ų5643 Ų4322%0.2224%0.244CC..G310 helixtrans-59-26.4177.376.6-90000112.5D667 V668 Q680 L683 V729Y665-D667 PolarHBondContact O-N 2.66Å; Y665-V668 VanDerWaalsContact O-CB 3.29Å; Y665-V668 WeakPolarHBondContact O-CB 3.32Å; Y665-V668 WeakPolarHBondContact O-CG2 3.41Å; Y665-V668 PolarHBondContact O-N 3.27Å; Y665-Q680 HydrophobicContact CE2-CB 4.12Å; Y665-Q680 HydrophobicContact CE2-CG 4.39Å; Y665-L683 HydrophobicContact CD1-CD1 3.88Å; Y665-L683 HydrophobicContact CD2-CD1 4.4Å; Y665-L683 HydrophobicContact CE1-CD1 3.72Å; Y665-L683 HydrophobicContact CE2-CD1 4.28Å; Y665-L683 HydrophobicContact CG-CD1 4.22Å; Y665-V729 HydrophobicContact CG-CG1 4.23Å
666Q78.6Confident82.3Confident86 Ų8643.4 Ų43.440%0.40225%0.248SC..G310 helixtrans-65-30.5175.8-66.1179.7-11.700111.9S664 V668 S669S664-Q666 PolarHBondContact O-N 2.87Å; S664-Q666 VanDerWaalsContact O-N 3.13Å; Q666-V668 PolarHBondContact O-N 2.95Å; Q666-S669 WeakPolarHBondContact O-CB 3.33Å; Q666-S669 PolarHBondContact O-N 2.88Å; Q666-S669 PolarHBondContact O-OG 3.33Å
667D82.8Confident81.9Confident16 Ų1649.4 Ų49.49%0.08627%0.274CS..G310 helixtrans-68.4-24.6179.3-59.3-51.5000111.7K656 S664 Y665 S669 S670 M737K656-D667 VanDerWaalsContact NZ-CG 3.26Å; K656-D667 IonicContact NZ-OD1 3.56Å; K656-D667 PolarHBondContact NZ-OD1 2.9Å; K656-D667 IonicContact NZ-OD2 2.67Å; K656-D667 PolarHBondContact NZ-OD2 2.88Å; S664-D667 PolarHBondContact N-OD2 3.39Å; S664-D667 WeakPolarHBondContact O-CB 3.38Å; S664-D667 PolarHBondContact O-N 3.27Å; Y665-D667 PolarHBondContact O-N 2.66Å; D667-S669 PolarHBondContact O-N 3.49Å; D667-S670 PolarHBondContact O-N 2.9Å; D667-S670 PolarHBondContact O-OG 2.72Å; D667-M737 HydrophobicContact CB-CE 4.24Å
668V82.8Confident81.5Confident3 Ų352.4 Ų52.42%0.01829%0.291CS..G310 helixtrans-60.5-27.5176-176.50000111.4Y665 Q666 S670 I671 D672 Y675 A676 L679 T733 M737Y665-V668 VanDerWaalsContact O-CB 3.29Å; Y665-V668 WeakPolarHBondContact O-CB 3.32Å; Y665-V668 WeakPolarHBondContact O-CG2 3.41Å; Y665-V668 PolarHBondContact O-N 3.27Å; Q666-V668 PolarHBondContact O-N 2.95Å; V668-S670 PolarHBondContact O-N 3.42Å; V668-S670 VanDerWaalsContact O-N 3.14Å; V668-I671 PolarHBondContact O-N 3.3Å; V668-D672 PolarHBondContact O-N 2.89Å; V668-Y675 HydrophobicContact CG1-CD1 4.06Å; V668-A676 HydrophobicContact CB-CB 4.21Å; V668-A676 HydrophobicContact CG1-CB 4.36Å; V668-L679 HydrophobicContact CG2-CD1 4.37Å; V668-T733 HydrophobicContact CG2-CG2 3.86Å; V668-M737 HydrophobicContact CG2-CG 4.07Å; V668-M737 HydrophobicContact CG2-SD 4.1Å
669S76.4Confident81.2Confident42 Ų4252.3 Ų52.329%0.29429%0.29SS..G310 helixtrans-60.3-25.2179.667.70000113.7Q666 D667 I671 P673Q666-S669 WeakPolarHBondContact O-CB 3.33Å; Q666-S669 PolarHBondContact O-N 2.88Å; Q666-S669 PolarHBondContact O-OG 3.33Å; D667-S669 PolarHBondContact O-N 3.49Å; S669-I671 VanDerWaalsContact C-N 3.3Å; S669-P673 WeakPolarHBondContact O-CG 3.49Å
670S73.2Confident80.9Confident12 Ų1256 Ų568%0.08431%0.307CS..G310 helixtrans-71.1-26.3175.164.10000112.9S607 A608 D667 V668S607-S670 WeakPolarHBondContact CB-O 3.24Å; A608-S670 PolarHBondContact N-O 3.2Å; D667-S670 PolarHBondContact O-N 2.9Å; D667-S670 PolarHBondContact O-OG 2.72Å; V668-S670 PolarHBondContact O-N 3.42Å; V668-S670 VanDerWaalsContact O-N 3.14Å
671I75.4Confident80.9Confident58 Ų5858.3 Ų58.330%0.29730%0.296SS..THydrogen-bonded Turntrans-94.9-53.9179.4-46.2-158.2000110.6V668 S669 M737V668-I671 PolarHBondContact O-N 3.3Å; S669-I671 VanDerWaalsContact C-N 3.3Å; I671-M737 HydrophobicContact CD1-CE 3.51Å; I671-M737 HydrophobicContact CD1-SD 3.2Å; I671-M737 WeakPolarHBondContact CD1-SD 3.27Å; I671-M737 HydrophobicContact CG1-CE 3.89Å; I671-M737 HydrophobicContact CG1-SD 3.82Å
672D78.9Confident80.8Confident65 Ų6557 Ų5735%0.34829%0.288SS..  trans-13991.9-174.2-169.3-26.3000109.4V668 E674 Y675 A676V668-D672 PolarHBondContact O-N 2.89Å; D672-E674 VanDerWaalsContact C-N 3.26Å; D672-E674 PolarHBondContact O-N 3.36Å; D672-E674 PolarHBondContact OD1-N 2.99Å; D672-Y675 PolarHBondContact O-N 3.2Å; D672-Y675 WeakPolarHBondContact OD1-CB 3.49Å; D672-Y675 PolarHBondContact OD1-N 3.2Å; D672-Y675 WeakPolarHBondContact OD2-CB 3.49Å; D672-A676 WeakPolarHBondContact O-CB 3.33Å; D672-A676 PolarHBondContact O-N 3.43Å
673P77.6Confident80.8Confident39 Ų3953.9 Ų53.925%0.25327%0.266SS..Hα-helixtrans-64.7-29.4-178.4-17.428.3000113.1A608 S669 K677 C864A608-P673 HydrophobicContact CB-CG 3.96Å; S669-P673 WeakPolarHBondContact O-CG 3.49Å; P673-K677 WeakPolarHBondContact O-CG 3.41Å; P673-K677 PolarHBondContact O-N 3.17Å; P673-C864 HydrophobicContact CG-CB 4.35Å; P673-C864 WeakPolarHBondContact CG-SG 3.21Å
674E78.8Confident80.7Confident143 Ų14357.9 Ų57.967%0.66829%0.286SS*.Hα-helixtrans-75.1-44.7-180-171.8173.9179.700110.1D672 A676 K677 N678D672-E674 VanDerWaalsContact C-N 3.26Å; D672-E674 PolarHBondContact O-N 3.36Å; D672-E674 PolarHBondContact OD1-N 2.99Å; E674-A676 PolarHBondContact O-N 3.14Å; E674-K677 WeakPolarHBondContact O-CB 3.4Å; E674-K677 PolarHBondContact O-N 3.2Å; E674-N678 PolarHBondContact O-N 2.83Å; E674-N678 VanDerWaalsContact O-N 3.09Å; E674-N678 PolarHBondContact O-ND2 3.16Å
675Y81.6Confident80.7Confident45 Ų4559.3 Ų59.318%0.17629%0.291CS..Hα-helixtrans-63.7-40.8175.5-164.3-101.9000112.3V668 D672 K677 N678 L679 V732 R736V668-Y675 HydrophobicContact CG1-CD1 4.06Å; D672-Y675 PolarHBondContact O-N 3.2Å; D672-Y675 WeakPolarHBondContact OD1-CB 3.49Å; D672-Y675 PolarHBondContact OD1-N 3.2Å; D672-Y675 WeakPolarHBondContact OD2-CB 3.49Å; Y675-K677 VanDerWaalsContact C-N 3.31Å; Y675-K677 PolarHBondContact O-N 3.32Å; Y675-N678 WeakPolarHBondContact O-CB 3.49Å; Y675-N678 PolarHBondContact O-N 2.88Å; Y675-N678 VanDerWaalsContact O-N 3.09Å; Y675-L679 HydrophobicContact CD1-CD1 3.85Å; Y675-L679 HydrophobicContact CD1-CG 4.06Å; Y675-L679 HydrophobicContact CE1-CD1 3.79Å; Y675-L679 HydrophobicContact CE1-CD2 4.03Å; Y675-L679 HydrophobicContact CE1-CG 3.98Å; Y675-L679 WeakPolarHBondContact O-CG 3.47Å; Y675-L679 PolarHBondContact O-N 3.26Å; Y675-V732 HydrophobicContact CE1-CG1 3.71Å; Y675-V732 WeakPolarHBondContact OH-CG1 3.45Å; Y675-R736 PolarHBondContact OH-NE 2.95Å
676A79.9Confident80.7Confident8 Ų861.2 Ų61.27%0.06631%0.305CS..Hα-helixtrans-60.3-39.3175.200000112.5V668 D672 E674 N678 L679 Q680V668-A676 HydrophobicContact CB-CB 4.21Å; V668-A676 HydrophobicContact CG1-CB 4.36Å; D672-A676 WeakPolarHBondContact O-CB 3.33Å; D672-A676 PolarHBondContact O-N 3.43Å; E674-A676 PolarHBondContact O-N 3.14Å; A676-N678 VanDerWaalsContact C-N 3.33Å; A676-L679 PolarHBondContact O-N 3.4Å; A676-Q680 WeakPolarHBondContact O-CB 3.31Å; A676-Q680 PolarHBondContact O-N 2.96Å
677K81.1Confident80.8Confident144 Ų14457.9 Ų57.963%0.62629%0.29SS*.Hα-helixtrans-62.9-39.9173-74.2170.9-174.1172.10111.8P673 E674 Y675 Q680 W681P673-K677 WeakPolarHBondContact O-CG 3.41Å; P673-K677 PolarHBondContact O-N 3.17Å; E674-K677 WeakPolarHBondContact O-CB 3.4Å; E674-K677 PolarHBondContact O-N 3.2Å; Y675-K677 VanDerWaalsContact C-N 3.31Å; Y675-K677 PolarHBondContact O-N 3.32Å; K677-Q680 PolarHBondContact O-N 2.87Å; K677-W681 WeakPolarHBondContact O-CB 3.48Å; K677-W681 PolarHBondContact O-N 2.79Å
678N84.1Confident80.5Confident86 Ų8660.9 Ų60.946%0.4631%0.312SS..Hα-helixtrans-65.3-42.2177.3-64.7-22.6000111.4E674 Y675 A676 W681 I682E674-N678 PolarHBondContact O-N 2.83Å; E674-N678 VanDerWaalsContact O-N 3.09Å; E674-N678 PolarHBondContact O-ND2 3.16Å; Y675-N678 WeakPolarHBondContact O-CB 3.49Å; Y675-N678 PolarHBondContact O-N 2.88Å; Y675-N678 VanDerWaalsContact O-N 3.09Å; A676-N678 VanDerWaalsContact C-N 3.33Å; N678-W681 WeakPolarHBondContact O-CB 3.12Å; N678-W681 PolarHBondContact O-N 3.22Å; N678-I682 WeakPolarHBondContact O-CG1 3.48Å; N678-I682 PolarHBondContact O-N 3.32Å
679L84.8Confident79.7Confident3 Ų368.2 Ų68.22%0.01635%0.352CS..Hα-helixtrans-62.7-44174.5-65.5178000111.9V668 Y675 A676 W681 I682 L683 V729 V732V668-L679 HydrophobicContact CG2-CD1 4.37Å; Y675-L679 HydrophobicContact CD1-CD1 3.85Å; Y675-L679 HydrophobicContact CD1-CG 4.06Å; Y675-L679 HydrophobicContact CE1-CD1 3.79Å; Y675-L679 HydrophobicContact CE1-CD2 4.03Å; Y675-L679 HydrophobicContact CE1-CG 3.98Å; Y675-L679 WeakPolarHBondContact O-CG 3.47Å; Y675-L679 PolarHBondContact O-N 3.26Å; A676-L679 PolarHBondContact O-N 3.4Å; L679-W681 VanDerWaalsContact C-N 3.32Å; L679-W681 PolarHBondContact O-N 3.36Å; L679-I682 PolarHBondContact O-N 3.4Å; L679-L683 PolarHBondContact O-N 2.87Å; L679-V729 HydrophobicContact CB-CG1 4.2Å; L679-V729 HydrophobicContact CD2-CG1 4.43Å; L679-V729 HydrophobicContact CD2-CG2 4.21Å; L679-V732 HydrophobicContact CD2-CG1 4.27Å
680Q83.4Confident79.1Confident88 Ų8870 Ų7041%0.41136%0.357SS..Hα-helixtrans-61.4-42.7175.2-177.7174.41.300111.3Y665 A676 K677 I682 L683 D684Y665-Q680 HydrophobicContact CE2-CB 4.12Å; Y665-Q680 HydrophobicContact CE2-CG 4.39Å; A676-Q680 WeakPolarHBondContact O-CB 3.31Å; A676-Q680 PolarHBondContact O-N 2.96Å; K677-Q680 PolarHBondContact O-N 2.87Å; Q680-I682 VanDerWaalsContact C-N 3.32Å; Q680-I682 PolarHBondContact O-N 3.04Å; Q680-L683 WeakPolarHBondContact O-CB 3.37Å; Q680-L683 PolarHBondContact O-N 3.17Å; Q680-L683 VanDerWaalsContact O-N 3.08Å; Q680-D684 WeakPolarHBondContact CG-OD2 3.38Å; Q680-D684 PolarHBondContact O-N 2.97Å
681W83.8Confident78.5Confident114 Ų11472.9 Ų72.943%0.43239%0.389SS..Hα-helixtrans-60.7-40.7177.6-172.790.7000112.1K677 N678 L679 L683 D684 N685 L690K677-W681 WeakPolarHBondContact O-CB 3.48Å; K677-W681 PolarHBondContact O-N 2.79Å; N678-W681 WeakPolarHBondContact O-CB 3.12Å; N678-W681 PolarHBondContact O-N 3.22Å; L679-W681 VanDerWaalsContact C-N 3.32Å; L679-W681 PolarHBondContact O-N 3.36Å; W681-L683 VanDerWaalsContact C-N 3.29Å; W681-L683 PolarHBondContact O-N 3.05Å; W681-D684 PolarHBondContact O-N 2.94Å; W681-N685 HydrophobicContact CD2-CB 4.31Å; W681-N685 HydrophobicContact CH2-CB 4.46Å; W681-N685 HydrophobicContact CZ2-CB 4.17Å; W681-N685 PolarHBondContact NE1-ND2 3.44Å; W681-N685 WeakPolarHBondContact O-CB 3.43Å; W681-N685 PolarHBondContact O-N 3.2Å; W681-N685 PolarHBondContact O-ND2 3.05Å; W681-L690 HydrophobicContact CH2-CD1 3.31Å; W681-L690 HydrophobicContact CH2-CD2 4.02Å; W681-L690 HydrophobicContact CH2-CG 4.32Å; W681-L690 HydrophobicContact CZ3-CD1 3.58Å
682I83.7Confident78.1Confident18 Ų1874.5 Ų74.59%0.09240%0.398CS..Hα-helixtrans-60.2-40.6174.2-69.3166000111N678 L679 Q680 I687 K725 V729N678-I682 WeakPolarHBondContact O-CG1 3.48Å; N678-I682 PolarHBondContact O-N 3.32Å; L679-I682 PolarHBondContact O-N 3.4Å; Q680-I682 VanDerWaalsContact C-N 3.32Å; Q680-I682 PolarHBondContact O-N 3.04Å; I682-I687 HydrophobicContact CG2-CG2 4.4Å; I682-K725 HydrophobicContact CG2-CB 4.06Å; I682-K725 HydrophobicContact CG2-CD 4.48Å; I682-K725 WeakPolarHBondContact O-CD 3.5Å; I682-K725 PolarHBondContact O-NZ 3.48Å; I682-V729 HydrophobicContact CG2-CG2 4.26Å
683L83.9Confident77.7Confident47 Ų4780 Ų8025%0.24642%0.421CS..Hα-helixtrans-67.6-43.6177.7-67.3175.1000111.8Y665 L679 Q680 W681 K725 A726 V729Y665-L683 HydrophobicContact CD1-CD1 3.88Å; Y665-L683 HydrophobicContact CD2-CD1 4.4Å; Y665-L683 HydrophobicContact CE1-CD1 3.72Å; Y665-L683 HydrophobicContact CE2-CD1 4.28Å; Y665-L683 HydrophobicContact CG-CD1 4.22Å; L679-L683 PolarHBondContact O-N 2.87Å; Q680-L683 WeakPolarHBondContact O-CB 3.37Å; Q680-L683 PolarHBondContact O-N 3.17Å; Q680-L683 VanDerWaalsContact O-N 3.08Å; W681-L683 VanDerWaalsContact C-N 3.29Å; W681-L683 PolarHBondContact O-N 3.05Å; L683-K725 PolarHBondContact O-NZ 2.88Å; L683-A726 HydrophobicContact CD2-CB 4.41Å; L683-V729 HydrophobicContact CD1-CG1 4.15Å; L683-V729 HydrophobicContact CD2-CB 4.28Å; L683-V729 HydrophobicContact CD2-CG2 4.01Å; L683-V729 HydrophobicContact CG-CG1 4.45Å; L683-V729 HydrophobicContact CG-CG2 4.13Å
684D81.1Confident77.8Confident110 Ų11080.4 Ų80.459%0.58842%0.421SS*.Hα-helixtrans-78.8-23.4-172.4-67.6-15.3000113.6Q680 W681Q680-D684 WeakPolarHBondContact CG-OD2 3.38Å; Q680-D684 PolarHBondContact O-N 2.97Å; W681-D684 PolarHBondContact O-N 2.94Å
685N83Confident78.1Confident62 Ų6275.2 Ų75.233%0.33240%0.399SS..SBendtrans-112.5156.3-173.3-62.7-91.6000112.9W681 K725W681-N685 HydrophobicContact CD2-CB 4.31Å; W681-N685 HydrophobicContact CH2-CB 4.46Å; W681-N685 HydrophobicContact CZ2-CB 4.17Å; W681-N685 PolarHBondContact NE1-ND2 3.44Å; W681-N685 WeakPolarHBondContact O-CB 3.43Å; W681-N685 PolarHBondContact O-N 3.2Å; W681-N685 PolarHBondContact O-ND2 3.05Å; N685-K725 PolarHBondContact O-NZ 3.44Å
686D80.6Confident78.4Confident96 Ų9673.1 Ų73.151%0.51339%0.391SS..  trans-77.8125.9171-169.4-10.7000109.8S688 Q722D686-S688 WeakPolarHBondContact OD1-CB 3.13Å; D686-S688 PolarHBondContact OD1-N 3.22Å; D686-S688 PolarHBondContact OD1-OG 2.84Å; D686-Q722 PolarHBondContact OD1-OE1 3.14Å
687I80.8Confident78.6Confident17 Ų1773.3 Ų73.39%0.08739%0.392CS..  trans-97.6-1-176.161.8171.8000114.2I682 D689 L690 V720 K725I682-I687 HydrophobicContact CG2-CG2 4.4Å; I687-D689 PolarHBondContact O-N 3.36Å; I687-L690 HydrophobicContact CB-CD1 4.19Å; I687-L690 HydrophobicContact CG2-CD1 4.09Å; I687-V720 HydrophobicContact CD1-CG1 3.88Å; I687-K725 HydrophobicContact CD1-CB 3.96Å; I687-K725 HydrophobicContact CD1-CD 4.29Å; I687-K725 HydrophobicContact CG1-CD 4.49Å
688S76.7Confident78.8Confident79 Ų7967 Ų6755%0.55237%0.365SS*.THydrogen-bonded Turntrans-65-32.2-171.2-52.40000114.4D686D686-S688 WeakPolarHBondContact OD1-CB 3.13Å; D686-S688 PolarHBondContact OD1-N 3.22Å; D686-S688 PolarHBondContact OD1-OG 2.84Å
689D64.7Low78.6Confident157 Ų15768.8 Ų68.884%0.8437%0.371SS*.THydrogen-bonded Turntrans-105.54.6-172.2-70.2-31000114.3I687I687-D689 PolarHBondContact O-N 3.36Å
690L64.1Low77.9Confident79 Ų7970 Ų7041%0.41438%0.379SS..SBendtrans-88-11.1-170-66.3167.7000114.8W681 I687 L692W681-L690 HydrophobicContact CH2-CD1 3.31Å; W681-L690 HydrophobicContact CH2-CD2 4.02Å; W681-L690 HydrophobicContact CH2-CG 4.32Å; W681-L690 HydrophobicContact CZ3-CD1 3.58Å; I687-L690 HydrophobicContact CB-CD1 4.19Å; I687-L690 HydrophobicContact CG2-CD1 4.09Å; L690-L692 HydrophobicContact CB-CD1 3.94Å; L690-L692 HydrophobicContact CB-CG 3.88Å; L690-L692 HydrophobicContact CD1-CD1 3.77Å; L690-L692 PolarHBondContact O-N 2.73Å
691G61.3Low77.1Confident73 Ų7370.5 Ų70.575%0.75338%0.384SS*.  trans6322.1-176.500000114.3E693G691-E693 PolarHBondContact O-N 3.09Å
692L66.6Low76.3Confident91 Ų9167.8 Ų67.848%0.47638%0.38SS..  trans-76.2106.9175.8-66.4170.1000109L690 L694L690-L692 HydrophobicContact CB-CD1 3.94Å; L690-L692 HydrophobicContact CB-CG 3.88Å; L690-L692 HydrophobicContact CD1-CD1 3.77Å; L690-L692 PolarHBondContact O-N 2.73Å; L692-L694 HydrophobicContact CB-CD1 4.14Å; L692-L694 HydrophobicContact CB-CG 4.11Å; L692-L694 HydrophobicContact CD1-CD1 4.29Å; L692-L694 PolarHBondContact O-N 3.45Å
693E69.5Low75Confident180 Ų18072.2 Ų72.284%0.84140%0.399SS*.  trans-75.354.8172.6-65.8-173.916900111.2G691G691-E693 PolarHBondContact O-N 3.09Å
694L79.8Confident73.8Confident48 Ų4873.3 Ų73.325%0.25142%0.421SS..  trans-76.3128.1177.1-71.1168.7000110.1L692 L719 V720L692-L694 HydrophobicContact CB-CD1 4.14Å; L692-L694 HydrophobicContact CB-CG 4.11Å; L692-L694 HydrophobicContact CD1-CD1 4.29Å; L692-L694 PolarHBondContact O-N 3.45Å; L694-L719 WeakPolarHBondContact O-CA 3.01Å; L694-V720 HydrophobicContact CB-CB 3.92Å; L694-V720 HydrophobicContact CB-CG2 3.79Å; L694-V720 PolarHBondContact O-N 2.92Å
695T86Confident73.1Confident35 Ų3570.4 Ų70.422%0.21541%0.413CS..BIsolated β-bridgetrans-109.8165.8172.550.20000111S697 I718 L719 Y728T695-S697 PolarHBondContact O-N 3.35Å; T695-S697 PolarHBondContact OG1-OG 3.09Å; T695-I718 CarbonylContact C-O 3.49Å; T695-I718 WeakPolarHBondContact CA-O 3.22Å; T695-L719 HydrophobicContact CG2-CD2 4.14Å; T695-Y728 VanDerWaalsContact O-CE2 3.29Å; T695-Y728 WeakPolarHBondContact O-CE2 3.45Å
696F87.6Confident72.7Confident0 Ų073.1 Ų73.10%043%0.425CS..SBendtrans-75.943.3170.8-82.3-105.1000112.2L711 K712 G715 I718 V720 N724 E727 Y728 L731F696-L711 HydrophobicContact CB-CB 4.44Å; F696-L711 HydrophobicContact CD1-CB 4.44Å; F696-L711 HydrophobicContact CD1-CD1 4.3Å; F696-L711 WeakPolarHBondContact O-CB 3.34Å; F696-L711 PolarHBondContact O-N 3.4Å; F696-K712 HydrophobicContact CB-CG 4.2Å; F696-K712 HydrophobicContact CD1-CD 3.9Å; F696-K712 HydrophobicContact CD1-CG 4.12Å; F696-K712 HydrophobicContact CE1-CD 4.26Å; F696-K712 HydrophobicContact CG-CD 4.36Å; F696-K712 HydrophobicContact CG-CG 4.38Å; F696-G715 CarbonylContact C-O 3.44Å; F696-G715 WeakPolarHBondContact CA-O 3.41Å; F696-G715 PolarHBondContact N-O 3.22Å; F696-G715 CarbonylContact O-C 3.55Å; F696-G715 WeakPolarHBondContact O-CA 3.42Å; F696-I718 HydrophobicContact CB-CB 4.39Å; F696-I718 HydrophobicContact CD2-CB 4.09Å; F696-I718 HydrophobicContact CD2-CG2 3.64Å; F696-I718 HydrophobicContact CE2-CG2 4.01Å; F696-I718 HydrophobicContact CG-CG2 4.41Å; F696-I718 PolarHBondContact N-O 3.42Å; F696-V720 HydrophobicContact CD2-CG2 4.03Å; F696-V720 HydrophobicContact CE2-CG2 3.99Å; F696-N724 HydrophobicContact CE2-CB 4.39Å; F696-N724 HydrophobicContact CZ-CB 4.08Å; F696-E727 HydrophobicContact CE1-CB 4.47Å; F696-E727 HydrophobicContact CE1-CG 4.3Å; F696-Y728 HydrophobicContact CD1-CD2 4.16Å; F696-Y728 HydrophobicContact CD2-CD2 4.47Å; F696-Y728 HydrophobicContact CE1-CD2 4.34Å; F696-Y728 HydrophobicContact CG-CD2 4.25Å; F696-L731 HydrophobicContact CD1-CD1 4.04Å; F696-L731 HydrophobicContact CE1-CD1 4.05Å
697S85.3Confident72.7Confident12 Ų1273.7 Ų73.78%0.08442%0.424CS..EExtended strand (participates in β ladder)trans-133.3148.4171.251.10000109.7T695 E708 V709T695-S697 PolarHBondContact O-N 3.35Å; T695-S697 PolarHBondContact OG1-OG 3.09Å; S697-E708 WeakPolarHBondContact CB-OE1 3.34Å; S697-E708 PolarHBondContact OG-OE1 2.81Å; S697-V709 WeakPolarHBondContact CA-O 3.19Å
698V83.7Confident72.7Confident11 Ų1178.4 Ų78.47%0.06745%0.446CS..EExtended strand (participates in β ladder)trans-133.4135.7-179.8-178.50000108.9T700 V709 L711 V732 L735V698-T700 HydrophobicContact CG1-CG2 4.44Å; V698-V709 PolarHBondContact N-O 2.91Å; V698-V709 PolarHBondContact O-N 3.43Å; V698-L711 HydrophobicContact CG2-CD1 4.1Å; V698-L711 HydrophobicContact CG2-CD2 4Å; V698-L711 HydrophobicContact CG2-CG 4.19Å; V698-V732 HydrophobicContact CG2-CG2 3.91Å; V698-L735 HydrophobicContact CB-CD2 4.36Å
699E80.2Confident73Confident125 Ų12576.7 Ų76.758%0.58443%0.432SS*.EExtended strand (participates in β ladder)trans-78.5126.9170.2-60.7-177.6171.100110.1M706 E707E699-M706 HydrophobicContact CB-CE 3.72Å; E699-E707 CarbonylContact C-O 3.53Å; E699-E707 WeakPolarHBondContact CA-O 3.28Å
700T70.6Confident74.1Confident29 Ų2972.6 Ų72.618%0.17841%0.414CS..EExtended strand (participates in β ladder)trans-122.9135.7177.455.90000110.6V698 V702 E707 V709 L735V698-T700 HydrophobicContact CG1-CG2 4.44Å; T700-V702 PolarHBondContact O-N 3.49Å; T700-E707 PolarHBondContact N-O 2.9Å; T700-E707 PolarHBondContact O-N 3.2Å; T700-V709 WeakPolarHBondContact OG1-CG2 3.34Å; T700-L735 HydrophobicContact CG2-CD2 4.38Å
701D67Low75.1Confident98 Ų9869 Ų6952%0.52440%0.395SS..EExtended strand (participates in β ladder)trans-76.7113.8173.5-176.2-3.6000110G704 M706D701-G704 WeakPolarHBondContact OD1-CA 3.41Å; D701-G704 PolarHBondContact OD1-N 3.48Å; D701-M706 HydrophobicContact CB-SD 3.98Å
702V65.6Low76.3Confident56 Ų5667.7 Ų67.734%0.33937%0.369SS..EExtended strand (participates in β ladder)trans-114.498.7172.7-175.10000107.6T700 G704 A705T700-V702 PolarHBondContact O-N 3.49Å; V702-G704 VanDerWaalsContact C-N 3.34Å; V702-G704 PolarHBondContact O-N 3.38Å; V702-A705 PolarHBondContact N-O 2.87Å; V702-A705 PolarHBondContact O-N 3.01Å; V702-A705 VanDerWaalsContact O-N 3.16Å
703F56.9Low77.2Confident112 Ų11269.4 Ų69.449%0.49139%0.385SS..THydrogen-bonded Turntrans57.137.7179.4-64-66.1000115.7N618 S620 V621 A705N618-F703 HydrophobicContact CB-CE1 3.65Å; N618-F703 HydrophobicContact CB-CZ 3.89Å; S620-F703 WeakPolarHBondContact OG-CZ 3.45Å; V621-F703 HydrophobicContact CG2-CD1 4.23Å; V621-F703 HydrophobicContact CG2-CE1 3.23Å; V621-F703 HydrophobicContact CG2-CZ 3.72Å; F703-A705 VanDerWaalsContact C-N 3.33Å
704G59.8Low77.9Confident69 Ų6963 Ų6371%0.71137%0.367SS*.THydrogen-bonded Turntrans85.43.5-179.600000113.9D701 V702D701-G704 WeakPolarHBondContact OD1-CA 3.41Å; D701-G704 PolarHBondContact OD1-N 3.48Å; V702-G704 VanDerWaalsContact C-N 3.34Å; V702-G704 PolarHBondContact O-N 3.38Å
705A64.8Low78.1Confident50 Ų5060.7 Ų60.741%0.41336%0.355SS..EExtended strand (participates in β ladder)trans-107.5124.5171.400000109.9V702 F703 E707V702-A705 PolarHBondContact N-O 2.87Å; V702-A705 PolarHBondContact O-N 3.01Å; V702-A705 VanDerWaalsContact O-N 3.16Å; F703-A705 VanDerWaalsContact C-N 3.33Å; A705-E707 PolarHBondContact O-N 2.86Å
706M75.4Confident77.9Confident118 Ų11862.3 Ų62.358%0.58137%0.368SS*.EExtended strand (participates in β ladder)trans-79.5116.3175.7-66.2-66.2-81.700109.3E699 D701E699-M706 HydrophobicContact CB-CE 3.72Å; D701-M706 HydrophobicContact CB-SD 3.98Å
707E79.6Confident77.7Confident109 Ų10967 Ų6751%0.50940%0.401SS..EExtended strand (participates in β ladder)trans-112.7137.1175.3-65.4-169.5167.300110.6E699 T700 A705E699-E707 CarbonylContact C-O 3.53Å; E699-E707 WeakPolarHBondContact CA-O 3.28Å; T700-E707 PolarHBondContact N-O 2.9Å; T700-E707 PolarHBondContact O-N 3.2Å; A705-E707 PolarHBondContact O-N 2.86Å
708E81.6Confident77.7Confident116 Ų11669 Ų6954%0.54241%0.41SS..EExtended strand (participates in β ladder)trans-85.5115.9174.7-171.2-173.9-174.400110.1S697S697-E708 WeakPolarHBondContact CB-OE1 3.34Å; S697-E708 PolarHBondContact OG-OE1 2.81Å
709V83.3Confident77.8Confident42 Ų4273.4 Ų73.426%0.25543%0.432SS..EExtended strand (participates in β ladder)trans-107.4119-178.9-176.60000110.1S697 V698 T700 L735S697-V709 WeakPolarHBondContact CA-O 3.19Å; V698-V709 PolarHBondContact N-O 2.91Å; V698-V709 PolarHBondContact O-N 3.43Å; T700-V709 WeakPolarHBondContact OG1-CG2 3.34Å; V709-L735 HydrophobicContact CB-CD2 4.34Å; V709-L735 HydrophobicContact CG1-CD1 4.05Å; V709-L735 HydrophobicContact CG1-CD2 4.19Å
710P86.4Confident78Confident71 Ų7168.2 Ų68.246%0.46141%0.409SS..EExtended strand (participates in β ladder)trans-73.1130.7174.829.2-33000110.9
711L85.5Confident78.7Confident4 Ų469.9 Ų69.92%0.02142%0.42CS..SBendtrans-72.1-32.1179.5-62.9175.3000112.7F696 V698 Y728 L731 V732 L735 R739F696-L711 HydrophobicContact CB-CB 4.44Å; F696-L711 HydrophobicContact CD1-CB 4.44Å; F696-L711 HydrophobicContact CD1-CD1 4.3Å; F696-L711 WeakPolarHBondContact O-CB 3.34Å; F696-L711 PolarHBondContact O-N 3.4Å; V698-L711 HydrophobicContact CG2-CD1 4.1Å; V698-L711 HydrophobicContact CG2-CD2 4Å; V698-L711 HydrophobicContact CG2-CG 4.19Å; L711-Y728 HydrophobicContact CD1-CD2 3.73Å; L711-Y728 HydrophobicContact CD1-CE2 3.69Å; L711-L731 HydrophobicContact CB-CB 4.06Å; L711-L731 HydrophobicContact CB-CD1 4.29Å; L711-L731 HydrophobicContact CD1-CB 4.3Å; L711-L731 HydrophobicContact CD2-CB 4.49Å; L711-V732 HydrophobicContact CD1-CG2 3.47Å; L711-V732 VanDerWaalsContact CD1-CG2 3.47Å; L711-V732 HydrophobicContact CD2-CG2 4.24Å; L711-V732 HydrophobicContact CG-CG2 4.5Å; L711-L735 HydrophobicContact CD2-CB 4.02Å; L711-L735 HydrophobicContact CD2-CD2 3.62Å; L711-L735 HydrophobicContact CD2-CG 4.42Å; L711-R739 PolarHBondContact O-NH1 3.07Å
712K86.5Confident79.5Confident45 Ų4568.6 Ų68.620%0.19641%0.411CS..SBendtrans-143.1164.4177.366.1-179.3172.3-170.40111F696 G714 G715 I718 E727 L731F696-K712 HydrophobicContact CB-CG 4.2Å; F696-K712 HydrophobicContact CD1-CD 3.9Å; F696-K712 HydrophobicContact CD1-CG 4.12Å; F696-K712 HydrophobicContact CE1-CD 4.26Å; F696-K712 HydrophobicContact CG-CD 4.36Å; F696-K712 HydrophobicContact CG-CG 4.38Å; K712-G714 PolarHBondContact O-N 2.97Å; K712-G715 WeakPolarHBondContact O-CA 3.34Å; K712-G715 PolarHBondContact O-N 2.9Å; K712-I718 HydrophobicContact CD-CD1 4.25Å; K712-I718 HydrophobicContact CG-CD1 4.18Å; K712-E727 VanDerWaalsContact NZ-CD 3.26Å; K712-E727 IonicContact NZ-OE1 2.8Å; K712-E727 PolarHBondContact NZ-OE1 3.07Å; K712-E727 IonicContact NZ-OE2 3.04Å; K712-E727 PolarHBondContact NZ-OE2 3.13Å; K712-L731 HydrophobicContact CB-CD1 4.33Å; K712-L731 HydrophobicContact CD-CD1 4.34Å
713P86.2Confident80.5Confident128 Ų12873.6 Ų73.683%0.83144%0.435SS*.THydrogen-bonded Turntrans-54.2124-179-26.235.4000112G715P713-G715 VanDerWaalsContact C-N 3.31Å
714G83.9Confident82Confident44 Ų4469.5 Ų69.545%0.45442%0.419SS..THydrogen-bonded Turntrans74.814.4-176.100000115.1K712 S716 S717K712-G714 PolarHBondContact O-N 2.97Å; G714-S716 VanDerWaalsContact C-N 3.26Å; G714-S716 PolarHBondContact O-N 3.05Å; G714-S716 VanDerWaalsContact O-N 3.11Å; G714-S717 PolarHBondContact O-N 2.78Å; G714-S717 PolarHBondContact O-OG 3.23Å
715G84.4Confident83.3Confident0 Ų067.1 Ų67.10%039%0.389CS..G310 helixtrans-53.5-32.7-171.300000116.2F696 K712 P713 S717 I718F696-G715 CarbonylContact C-O 3.44Å; F696-G715 WeakPolarHBondContact CA-O 3.41Å; F696-G715 PolarHBondContact N-O 3.22Å; F696-G715 CarbonylContact O-C 3.55Å; F696-G715 WeakPolarHBondContact O-CA 3.42Å; K712-G715 WeakPolarHBondContact O-CA 3.34Å; K712-G715 PolarHBondContact O-N 2.9Å; P713-G715 VanDerWaalsContact C-N 3.31Å; G715-S717 PolarHBondContact O-N 2.97Å; G715-S717 VanDerWaalsContact O-N 3.15Å; G715-I718 PolarHBondContact O-N 2.75Å; G715-I718 VanDerWaalsContact O-N 3.15Å
716S82.1Confident84.3Confident70 Ų7067.6 Ų67.649%0.4939%0.393SS..G310 helixtrans-64.7-14.5175.852.10000114.3G714G714-S716 VanDerWaalsContact C-N 3.26Å; G714-S716 PolarHBondContact O-N 3.05Å; G714-S716 VanDerWaalsContact O-N 3.11Å
717S82.3Confident84.9Confident98 Ų9865.8 Ų65.869%0.68538%0.383SS*.G310 helixtrans-105.6-4.9176.965.30000114.2G714 G715G714-S717 PolarHBondContact O-N 2.78Å; G714-S717 PolarHBondContact O-OG 3.23Å; G715-S717 PolarHBondContact O-N 2.97Å; G715-S717 VanDerWaalsContact O-N 3.15Å
718I86.4Confident85.3Confident54 Ų5461.3 Ų61.328%0.27736%0.362SS..PPolyproline II helixtrans-102.6116.5-175.2-57173000108.7T695 F696 K712 G715T695-I718 CarbonylContact C-O 3.49Å; T695-I718 WeakPolarHBondContact CA-O 3.22Å; F696-I718 HydrophobicContact CB-CB 4.39Å; F696-I718 HydrophobicContact CD2-CB 4.09Å; F696-I718 HydrophobicContact CD2-CG2 3.64Å; F696-I718 HydrophobicContact CE2-CG2 4.01Å; F696-I718 HydrophobicContact CG-CG2 4.41Å; F696-I718 PolarHBondContact N-O 3.42Å; K712-I718 HydrophobicContact CD-CD1 4.25Å; K712-I718 HydrophobicContact CG-CD1 4.18Å; G715-I718 PolarHBondContact O-N 2.75Å; G715-I718 VanDerWaalsContact O-N 3.15Å
719L84.3Confident85.5Confident103 Ų10356 Ų5654%0.53934%0.337SS..BIsolated β-bridgetrans-76.4144.9176.6-69170.9000112.1L694 T695 N724L694-L719 WeakPolarHBondContact O-CA 3.01Å; T695-L719 HydrophobicContact CG2-CD2 4.14Å; L719-N724 PolarHBondContact O-ND2 3.39Å
720V85.3Confident85.6Confident16 Ų1660.3 Ų60.310%0.09735%0.354CS..PPolyproline II helixtrans-78.4124.5171-174.10000109I687 L694 F696 N724 K725 Y728I687-V720 HydrophobicContact CD1-CG1 3.88Å; L694-V720 HydrophobicContact CB-CB 3.92Å; L694-V720 HydrophobicContact CB-CG2 3.79Å; L694-V720 PolarHBondContact O-N 2.92Å; F696-V720 HydrophobicContact CD2-CG2 4.03Å; F696-V720 HydrophobicContact CE2-CG2 3.99Å; V720-N724 VanDerWaalsContact CA-OD1 3.29Å; V720-N724 WeakPolarHBondContact CA-OD1 3.46Å; V720-K725 HydrophobicContact CG1-CB 4.14Å; V720-Y728 HydrophobicContact CG1-CD1 4.35Å; V720-Y728 HydrophobicContact CG1-CG 4.13Å; V720-Y728 HydrophobicContact CG2-CD1 4.29Å; V720-Y728 HydrophobicContact CG2-CD2 3.44Å; V720-Y728 VanDerWaalsContact CG2-CD2 3.44Å; V720-Y728 HydrophobicContact CG2-CE2 3.83Å; V720-Y728 HydrophobicContact CG2-CG 3.7Å
721T85.8Confident85.6Confident65 Ų6558 Ų5840%0.39934%0.338SS..  trans-124.2168.4-17969.20000110.1D723 N724 K725T721-D723 PolarHBondContact O-N 2.85Å; T721-D723 VanDerWaalsContact O-N 3.17Å; T721-N724 PolarHBondContact N-OD1 3.48Å; T721-N724 PolarHBondContact O-N 3.44Å; T721-N724 VanDerWaalsContact O-N 3.12Å; T721-N724 PolarHBondContact O-OD1 3.05Å; T721-N724 PolarHBondContact OG1-ND2 3.03Å; T721-K725 WeakPolarHBondContact O-CB 3.38Å; T721-K725 PolarHBondContact O-N 3.15Å
722Q84.1Confident85.6Confident71 Ų7157.8 Ų57.833%0.33234%0.337SS..THydrogen-bonded Turntrans-56.2-33.9179-170.565.45.400113.1D686 K725D686-Q722 PolarHBondContact OD1-OE1 3.14Å; Q722-K725 WeakPolarHBondContact O-CG 3.33Å
723D85.8Confident85.5Confident160 Ų16055.8 Ų55.886%0.85633%0.329SS*.THydrogen-bonded Turntrans-77.1-26.9-179.1-62.6-35.2000113.4T721T721-D723 PolarHBondContact O-N 2.85Å; T721-D723 VanDerWaalsContact O-N 3.17Å
724N88.6Confident85.4Confident27 Ų2752.8 Ų52.814%0.14430%0.303CS..THydrogen-bonded Turntrans-111.2-1.8-173.674.824.4000113.9F696 L719 V720 T721 A726 E727 Y728F696-N724 HydrophobicContact CE2-CB 4.39Å; F696-N724 HydrophobicContact CZ-CB 4.08Å; L719-N724 PolarHBondContact O-ND2 3.39Å; V720-N724 VanDerWaalsContact CA-OD1 3.29Å; V720-N724 WeakPolarHBondContact CA-OD1 3.46Å; T721-N724 PolarHBondContact N-OD1 3.48Å; T721-N724 PolarHBondContact O-N 3.44Å; T721-N724 VanDerWaalsContact O-N 3.12Å; T721-N724 PolarHBondContact O-OD1 3.05Å; T721-N724 PolarHBondContact OG1-ND2 3.03Å; N724-A726 PolarHBondContact O-N 2.93Å; N724-E727 WeakPolarHBondContact O-CB 3.39Å; N724-E727 PolarHBondContact O-N 3.46Å; N724-E727 VanDerWaalsContact O-N 3.08Å; N724-Y728 PolarHBondContact O-N 2.87Å
725K86.9Confident85.4Confident18 Ų1851.5 Ų51.58%0.07829%0.286CS..Hα-helixtrans-58.6-33.1-178.370.9-176.2-170.3158.40113.8I682 L683 N685 I687 V720 T721 Q722 Y728 V729I682-K725 HydrophobicContact CG2-CB 4.06Å; I682-K725 HydrophobicContact CG2-CD 4.48Å; I682-K725 WeakPolarHBondContact O-CD 3.5Å; I682-K725 PolarHBondContact O-NZ 3.48Å; L683-K725 PolarHBondContact O-NZ 2.88Å; N685-K725 PolarHBondContact O-NZ 3.44Å; I687-K725 HydrophobicContact CD1-CB 3.96Å; I687-K725 HydrophobicContact CD1-CD 4.29Å; I687-K725 HydrophobicContact CG1-CD 4.49Å; V720-K725 HydrophobicContact CG1-CB 4.14Å; T721-K725 WeakPolarHBondContact O-CB 3.38Å; T721-K725 PolarHBondContact O-N 3.15Å; Q722-K725 WeakPolarHBondContact O-CG 3.33Å; K725-Y728 PolarHBondContact O-N 3.26Å; K725-V729 VanDerWaalsContact O-CG2 3.32Å; K725-V729 WeakPolarHBondContact O-CG2 3.29Å; K725-V729 PolarHBondContact O-N 2.99Å
726A85.7Confident85.2Confident61 Ų6156 Ų5650%0.50430%0.303SS..Hα-helixtrans-67.2-42.1176.100000111.9L683 N724 V729 Q730L683-A726 HydrophobicContact CD2-CB 4.41Å; N724-A726 PolarHBondContact O-N 2.93Å; A726-V729 PolarHBondContact O-N 3.46Å; A726-Q730 PolarHBondContact O-N 2.87Å
727E87.9Confident85.2Confident80 Ų8052.9 Ų52.937%0.37428%0.281SS..Hα-helixtrans-63.5-42.6174.4-171.4-160.1160.500110.8F696 K712 N724 Q730 L731F696-E727 HydrophobicContact CE1-CB 4.47Å; F696-E727 HydrophobicContact CE1-CG 4.3Å; K712-E727 VanDerWaalsContact NZ-CD 3.26Å; K712-E727 IonicContact NZ-OE1 2.8Å; K712-E727 PolarHBondContact NZ-OE1 3.07Å; K712-E727 IonicContact NZ-OE2 3.04Å; K712-E727 PolarHBondContact NZ-OE2 3.13Å; N724-E727 WeakPolarHBondContact O-CB 3.39Å; N724-E727 PolarHBondContact O-N 3.46Å; N724-E727 VanDerWaalsContact O-N 3.08Å; E727-Q730 PolarHBondContact O-N 2.85Å; E727-L731 HydrophobicContact CG-CD1 4.13Å; E727-L731 WeakPolarHBondContact O-CG 3.42Å; E727-L731 PolarHBondContact O-N 3.36Å
728Y88Confident85.3Confident15 Ų1549 Ų496%0.05925%0.253CS..Hα-helixtrans-56.8-53.2175.1174.6-100.1000111.3T695 F696 L711 V720 N724 K725 Q730 L731 V732T695-Y728 VanDerWaalsContact O-CE2 3.29Å; T695-Y728 WeakPolarHBondContact O-CE2 3.45Å; F696-Y728 HydrophobicContact CD1-CD2 4.16Å; F696-Y728 HydrophobicContact CD2-CD2 4.47Å; F696-Y728 HydrophobicContact CE1-CD2 4.34Å; F696-Y728 HydrophobicContact CG-CD2 4.25Å; L711-Y728 HydrophobicContact CD1-CD2 3.73Å; L711-Y728 HydrophobicContact CD1-CE2 3.69Å; V720-Y728 HydrophobicContact CG1-CD1 4.35Å; V720-Y728 HydrophobicContact CG1-CG 4.13Å; V720-Y728 HydrophobicContact CG2-CD1 4.29Å; V720-Y728 HydrophobicContact CG2-CD2 3.44Å; V720-Y728 VanDerWaalsContact CG2-CD2 3.44Å; V720-Y728 HydrophobicContact CG2-CE2 3.83Å; V720-Y728 HydrophobicContact CG2-CG 3.7Å; N724-Y728 PolarHBondContact O-N 2.87Å; K725-Y728 PolarHBondContact O-N 3.26Å; Y728-Q730 VanDerWaalsContact C-N 3.29Å; Y728-Q730 PolarHBondContact O-N 2.9Å; Y728-L731 PolarHBondContact O-N 3.43Å; Y728-V732 HydrophobicContact CD1-CG2 4.22Å; Y728-V732 HydrophobicContact CD2-CG2 4.12Å; Y728-V732 HydrophobicContact CE1-CG2 3.85Å; Y728-V732 HydrophobicContact CE2-CG2 3.74Å; Y728-V732 HydrophobicContact CG-CG2 4.34Å; Y728-V732 WeakPolarHBondContact O-CB 3.47Å; Y728-V732 VanDerWaalsContact O-CG2 3.27Å; Y728-V732 WeakPolarHBondContact O-CG2 3.44Å; Y728-V732 PolarHBondContact O-N 2.98Å
729V86.6Confident85.2Confident4 Ų451 Ų512%0.02426%0.257CS..Hα-helixtrans-59.5-40.7179.9171.80000111.4Y665 L679 I682 L683 K725 A726 T733Y665-V729 HydrophobicContact CG-CG1 4.23Å; L679-V729 HydrophobicContact CB-CG1 4.2Å; L679-V729 HydrophobicContact CD2-CG1 4.43Å; L679-V729 HydrophobicContact CD2-CG2 4.21Å; I682-V729 HydrophobicContact CG2-CG2 4.26Å; L683-V729 HydrophobicContact CD1-CG1 4.15Å; L683-V729 HydrophobicContact CD2-CB 4.28Å; L683-V729 HydrophobicContact CD2-CG2 4.01Å; L683-V729 HydrophobicContact CG-CG1 4.45Å; L683-V729 HydrophobicContact CG-CG2 4.13Å; K725-V729 VanDerWaalsContact O-CG2 3.32Å; K725-V729 WeakPolarHBondContact O-CG2 3.29Å; K725-V729 PolarHBondContact O-N 2.99Å; A726-V729 PolarHBondContact O-N 3.46Å; V729-T733 WeakPolarHBondContact O-CB 3.39Å; V729-T733 PolarHBondContact O-N 3.38Å; V729-T733 PolarHBondContact O-OG1 3.26Å
730Q85.7Confident85Confident132 Ų13248.6 Ų48.662%0.61725%0.252SS*.Hα-helixtrans-62.8-48.7176.6-175.4179.53.400112.1A726 E727 Y728 T733 E734A726-Q730 PolarHBondContact O-N 2.87Å; E727-Q730 PolarHBondContact O-N 2.85Å; Y728-Q730 VanDerWaalsContact C-N 3.29Å; Y728-Q730 PolarHBondContact O-N 2.9Å; Q730-T733 WeakPolarHBondContact O-CB 3.24Å; Q730-T733 PolarHBondContact O-N 3.28Å; Q730-E734 PolarHBondContact O-N 3.43Å
731L85.7Confident85.1Confident22 Ų2248.5 Ų48.512%0.11525%0.251CS..Hα-helixtrans-68.5-36.9-178.2-70.2173.8000112.6F696 L711 K712 E727 Y728 T733 E734 L735F696-L731 HydrophobicContact CD1-CD1 4.04Å; F696-L731 HydrophobicContact CE1-CD1 4.05Å; L711-L731 HydrophobicContact CB-CB 4.06Å; L711-L731 HydrophobicContact CB-CD1 4.29Å; L711-L731 HydrophobicContact CD1-CB 4.3Å; L711-L731 HydrophobicContact CD2-CB 4.49Å; K712-L731 HydrophobicContact CB-CD1 4.33Å; K712-L731 HydrophobicContact CD-CD1 4.34Å; E727-L731 HydrophobicContact CG-CD1 4.13Å; E727-L731 WeakPolarHBondContact O-CG 3.42Å; E727-L731 PolarHBondContact O-N 3.36Å; Y728-L731 PolarHBondContact O-N 3.43Å; L731-T733 VanDerWaalsContact C-N 3.32Å; L731-E734 PolarHBondContact O-N 3.2Å; L731-L735 WeakPolarHBondContact O-CB 3.32Å; L731-L735 PolarHBondContact O-N 2.81Å
732V85.4Confident85.2Confident1 Ų148.7 Ų48.71%0.00625%0.247CC..Hα-helixtrans-61.7-43.9172.5170.10000110.6Y675 L679 V698 L711 Y728 L735 R736Y675-V732 HydrophobicContact CE1-CG1 3.71Å; Y675-V732 WeakPolarHBondContact OH-CG1 3.45Å; L679-V732 HydrophobicContact CD2-CG1 4.27Å; V698-V732 HydrophobicContact CG2-CG2 3.91Å; L711-V732 HydrophobicContact CD1-CG2 3.47Å; L711-V732 VanDerWaalsContact CD1-CG2 3.47Å; L711-V732 HydrophobicContact CD2-CG2 4.24Å; L711-V732 HydrophobicContact CG-CG2 4.5Å; Y728-V732 HydrophobicContact CD1-CG2 4.22Å; Y728-V732 HydrophobicContact CD2-CG2 4.12Å; Y728-V732 HydrophobicContact CE1-CG2 3.85Å; Y728-V732 HydrophobicContact CE2-CG2 3.74Å; Y728-V732 HydrophobicContact CG-CG2 4.34Å; Y728-V732 WeakPolarHBondContact O-CB 3.47Å; Y728-V732 VanDerWaalsContact O-CG2 3.27Å; Y728-V732 WeakPolarHBondContact O-CG2 3.44Å; Y728-V732 PolarHBondContact O-N 2.98Å; V732-L735 PolarHBondContact O-N 2.78Å; V732-R736 PolarHBondContact O-N 2.95Å; V732-R736 VanDerWaalsContact O-N 3.09Å
733T85.1Confident85.5Confident3 Ų348.7 Ų48.72%0.01825%0.253CS..Hα-helixtrans-61.3-48.8176.8-59.70000110.6V663 S664 V668 V729 Q730 L731 L735 R736 M737V663-T733 HydrophobicContact CG2-CG2 4.22Å; S664-T733 WeakPolarHBondContact O-CG2 3.4Å; V668-T733 HydrophobicContact CG2-CG2 3.86Å; V729-T733 WeakPolarHBondContact O-CB 3.39Å; V729-T733 PolarHBondContact O-N 3.38Å; V729-T733 PolarHBondContact O-OG1 3.26Å; Q730-T733 WeakPolarHBondContact O-CB 3.24Å; Q730-T733 PolarHBondContact O-N 3.28Å; L731-T733 VanDerWaalsContact C-N 3.32Å; T733-L735 VanDerWaalsContact C-N 3.34Å; T733-L735 PolarHBondContact O-N 3.14Å; T733-R736 PolarHBondContact O-N 3.25Å; T733-M737 HydrophobicContact CG2-CG 4.08Å; T733-M737 VanDerWaalsContact O-CB 3.28Å; T733-M737 WeakPolarHBondContact O-CB 3.4Å; T733-M737 VanDerWaalsContact O-CG 3.23Å; T733-M737 WeakPolarHBondContact O-CG 3.49Å; T733-M737 PolarHBondContact O-N 3.41Å
734E84.6Confident85.9Confident65 Ų6541.4 Ų41.430%0.30421%0.214SC..Hα-helixtrans-61.1-41.1178.4-166.9-160.9140.300112.1Q730 L731 T738 R739Q730-E734 PolarHBondContact O-N 3.43Å; L731-E734 PolarHBondContact O-N 3.2Å; E734-T738 WeakPolarHBondContact O-CA 3.36Å; E734-T738 WeakPolarHBondContact O-CB 3.16Å; E734-T738 PolarHBondContact O-N 3.12Å; E734-R739 VanDerWaalsContact CD-NH2 3.33Å; E734-R739 HydrophobicContact CG-CG 4.39Å; E734-R739 PolarHBondContact O-N 2.74Å; E734-R739 IonicContact OE1-CZ 2.81Å; E734-R739 IonicContact OE1-NE 2.62Å; E734-R739 PolarHBondContact OE1-NE 3.43Å; E734-R739 IonicContact OE1-NH2 2.61Å; E734-R739 PolarHBondContact OE1-NH2 3.41Å; E734-R739 IonicContact OE2-CZ 3.61Å; E734-R739 IonicContact OE2-NH2 3.02Å; E734-R739 PolarHBondContact OE2-NH2 3.42Å; E734-R739 VanDerWaalsContact OE2-NH2 3.16Å
735L83.6Confident86.1Confident17 Ų1740.3 Ų40.39%0.08921%0.208CC..Hα-helixtrans-59.7-51.6177.2177.465.2000111.1V698 T700 V709 L711 L731 V732 T733 R739 A740V698-L735 HydrophobicContact CB-CD2 4.36Å; T700-L735 HydrophobicContact CG2-CD2 4.38Å; V709-L735 HydrophobicContact CB-CD2 4.34Å; V709-L735 HydrophobicContact CG1-CD1 4.05Å; V709-L735 HydrophobicContact CG1-CD2 4.19Å; L711-L735 HydrophobicContact CD2-CB 4.02Å; L711-L735 HydrophobicContact CD2-CD2 3.62Å; L711-L735 HydrophobicContact CD2-CG 4.42Å; L731-L735 WeakPolarHBondContact O-CB 3.32Å; L731-L735 PolarHBondContact O-N 2.81Å; V732-L735 PolarHBondContact O-N 2.78Å; T733-L735 VanDerWaalsContact C-N 3.34Å; T733-L735 PolarHBondContact O-N 3.14Å; L735-R739 HydrophobicContact CD1-CB 4.09Å; L735-A740 PolarHBondContact O-N 3.43Å
736R80.4Confident86.5Confident94 Ų9443.5 Ų43.536%0.35523%0.226SC..Hα-helixtrans-72.4-38.3-174.2-71.4-172176-82.1-4.2113.2Y675 V732 T733Y675-R736 PolarHBondContact OH-NE 2.95Å; V732-R736 PolarHBondContact O-N 2.95Å; V732-R736 VanDerWaalsContact O-N 3.09Å; T733-R736 PolarHBondContact O-N 3.25Å
737M81.6Confident86.9Confident4 Ų441 Ų412%0.0221%0.205CC..Hα-helixtrans-95.4-19.2-172.4-56.9-61.5-67.300113.6S653 H657 V663 D667 V668 I671 T733 I741S653-M737 WeakPolarHBondContact OG-CE 3.27Å; H657-M737 PolarHBondContact NE2-O 3.07Å; V663-M737 HydrophobicContact CG2-CB 4.02Å; D667-M737 HydrophobicContact CB-CE 4.24Å; V668-M737 HydrophobicContact CG2-CG 4.07Å; V668-M737 HydrophobicContact CG2-SD 4.1Å; I671-M737 HydrophobicContact CD1-CE 3.51Å; I671-M737 HydrophobicContact CD1-SD 3.2Å; I671-M737 WeakPolarHBondContact CD1-SD 3.27Å; I671-M737 HydrophobicContact CG1-CE 3.89Å; I671-M737 HydrophobicContact CG1-SD 3.82Å; T733-M737 HydrophobicContact CG2-CG 4.08Å; T733-M737 VanDerWaalsContact O-CB 3.28Å; T733-M737 WeakPolarHBondContact O-CB 3.4Å; T733-M737 VanDerWaalsContact O-CG 3.23Å; T733-M737 WeakPolarHBondContact O-CG 3.49Å; T733-M737 PolarHBondContact O-N 3.41Å; M737-I741 WeakPolarHBondContact O-CD1 3.42Å
738T83.5Confident87.3Confident18 Ų1837.2 Ų37.211%0.1119%0.188CC..THydrogen-bonded Turntrans-130.3-62.4-168.3-430000111.8H657 E734 A740 I741 Q742H657-T738 PolarHBondContact CE1-OG1 3.38Å; E734-T738 WeakPolarHBondContact O-CA 3.36Å; E734-T738 WeakPolarHBondContact O-CB 3.16Å; E734-T738 PolarHBondContact O-N 3.12Å; T738-A740 VanDerWaalsContact C-N 3.33Å; T738-A740 PolarHBondContact O-N 2.97Å; T738-I741 CarbonylContact O-C 3.53Å; T738-I741 PolarHBondContact O-N 2.89Å; T738-I741 VanDerWaalsContact O-N 3.11Å; T738-Q742 VanDerWaalsContact CG2-OE1 3.3Å; T738-Q742 PolarHBondContact O-N 3.27Å
739R83.9Confident87.7Confident96 Ų9638 Ų3836%0.36219%0.193SC..G310 helixtrans-61.9-39.6-170.6-63.1-176.1-178.81726.4112.7L711 E734 L735 I741L711-R739 PolarHBondContact O-NH1 3.07Å; E734-R739 VanDerWaalsContact CD-NH2 3.33Å; E734-R739 HydrophobicContact CG-CG 4.39Å; E734-R739 PolarHBondContact O-N 2.74Å; E734-R739 IonicContact OE1-CZ 2.81Å; E734-R739 IonicContact OE1-NE 2.62Å; E734-R739 PolarHBondContact OE1-NE 3.43Å; E734-R739 IonicContact OE1-NH2 2.61Å; E734-R739 PolarHBondContact OE1-NH2 3.41Å; E734-R739 IonicContact OE2-CZ 3.61Å; E734-R739 IonicContact OE2-NH2 3.02Å; E734-R739 PolarHBondContact OE2-NH2 3.42Å; E734-R739 VanDerWaalsContact OE2-NH2 3.16Å; L735-R739 HydrophobicContact CD1-CB 4.09Å; R739-I741 PolarHBondContact O-N 3.37Å
740A80Confident88.1Confident51 Ų5143.5 Ų43.542%0.42122%0.218SC..G310 helixtrans-64.7-23.6179.900000114.1L735 T738L735-A740 PolarHBondContact O-N 3.43Å; T738-A740 VanDerWaalsContact C-N 3.33Å; T738-A740 PolarHBondContact O-N 2.97Å
741I87.4Confident88.4Confident15 Ų1537.2 Ų37.28%0.07719%0.189CC..G310 helixtrans-12314-17654.7164.8000113.2P615 M737 T738 R739 Q744 I745P615-I741 HydrophobicContact CB-CB 4.3Å; P615-I741 HydrophobicContact CB-CD1 3.96Å; P615-I741 HydrophobicContact CB-CG2 4.27Å; P615-I741 HydrophobicContact CG-CD1 3.97Å; M737-I741 WeakPolarHBondContact O-CD1 3.42Å; T738-I741 CarbonylContact O-C 3.53Å; T738-I741 PolarHBondContact O-N 2.89Å; T738-I741 VanDerWaalsContact O-N 3.11Å; R739-I741 PolarHBondContact O-N 3.37Å; I741-Q744 VanDerWaalsContact CA-OE1 3.26Å; I741-Q744 WeakPolarHBondContact O-CB 3.41Å; I741-Q744 PolarHBondContact O-N 3.07Å; I741-Q744 VanDerWaalsContact O-N 3.16Å; I741-Q744 PolarHBondContact O-OE1 3.41Å; I741-Q744 VanDerWaalsContact O-OE1 3.12Å; I741-I745 HydrophobicContact CD1-CD1 3.79Å; I741-I745 HydrophobicContact CD1-CG1 4.23Å; I741-I745 HydrophobicContact CG1-CD1 3.76Å; I741-I745 HydrophobicContact CG1-CG1 4.34Å; I741-I745 WeakPolarHBondContact O-CG1 3.23Å; I741-I745 PolarHBondContact O-N 3.14Å
742Q88.7Confident88.9Confident69 Ų6936.1 Ų36.132%0.32218%0.183SC..Hα-helixtrans-58.9-44.3-174.7-171.971.661.100113.4T738 Q744 I745 N746T738-Q742 VanDerWaalsContact CG2-OE1 3.3Å; T738-Q742 PolarHBondContact O-N 3.27Å; Q742-Q744 VanDerWaalsContact C-N 3.28Å; Q742-Q744 PolarHBondContact O-N 3.46Å; Q742-I745 PolarHBondContact O-N 2.8Å; Q742-N746 PolarHBondContact NE2-OD1 3.39Å; Q742-N746 WeakPolarHBondContact O-CB 3.45Å; Q742-N746 PolarHBondContact O-N 3.23Å; Q742-N746 PolarHBondContact O-ND2 2.84Å; Q742-N746 PolarHBondContact O-OD1 2.95Å
743P90.8Very high89.2Confident70 Ų7038.7 Ų38.746%0.45520%0.195SC..Hα-helixtrans-57.9-40175.7-25.535.1000113.2L626 N746 A747L626-P743 HydrophobicContact CD2-CB 3.9Å; P743-N746 PolarHBondContact O-N 2.7Å; P743-A747 WeakPolarHBondContact O-CB 3.41Å; P743-A747 PolarHBondContact O-N 2.91Å
744Q93.3Very high89.5Confident8 Ų840.2 Ų40.24%0.03720%0.204CC..Hα-helixtrans-66.9-47.1-179.9-61.186.3-36.200110.7S619 L626 F629 I741 Q742 N746 A747 F748S619-Q744 WeakPolarHBondContact OG-CG 3.28Å; S619-Q744 PolarHBondContact OG-NE2 3.28Å; S619-Q744 VanDerWaalsContact OG-NE2 3.12Å; L626-Q744 HydrophobicContact CD2-CG 4.49Å; F629-Q744 HydrophobicContact CD1-CB 4.25Å; F629-Q744 HydrophobicContact CD2-CB 3.77Å; F629-Q744 HydrophobicContact CD2-CG 3.76Å; F629-Q744 HydrophobicContact CE1-CB 4.09Å; F629-Q744 HydrophobicContact CE2-CB 3.62Å; F629-Q744 HydrophobicContact CE2-CG 3.32Å; F629-Q744 HydrophobicContact CG-CB 4.09Å; F629-Q744 HydrophobicContact CZ-CB 3.75Å; F629-Q744 HydrophobicContact CZ-CG 3.77Å; I741-Q744 VanDerWaalsContact CA-OE1 3.26Å; I741-Q744 WeakPolarHBondContact O-CB 3.41Å; I741-Q744 PolarHBondContact O-N 3.07Å; I741-Q744 VanDerWaalsContact O-N 3.16Å; I741-Q744 PolarHBondContact O-OE1 3.41Å; I741-Q744 VanDerWaalsContact O-OE1 3.12Å; Q742-Q744 VanDerWaalsContact C-N 3.28Å; Q742-Q744 PolarHBondContact O-N 3.46Å; Q744-N746 PolarHBondContact O-N 3.34Å; Q744-A747 PolarHBondContact O-N 3.15Å; Q744-F748 WeakPolarHBondContact O-CB 3.23Å; Q744-F748 PolarHBondContact O-N 3.24Å
745I93.1Very high89.7Confident4 Ų437.3 Ų37.32%0.02119%0.19CC..Hα-helixtrans-58.8-47.7175.8-67.6166000110.3F654 H657 I741 Q742 A747 F748 L749F654-I745 HydrophobicContact CE2-CG1 4.25Å; H657-I745 HydrophobicContact CB-CD1 4.3Å; H657-I745 HydrophobicContact CB-CG2 4.1Å; H657-I745 VanDerWaalsContact CD2-CD1 3.46Å; H657-I745 WeakPolarHBondContact CD2-CD1 3.46Å; I741-I745 HydrophobicContact CD1-CD1 3.79Å; I741-I745 HydrophobicContact CD1-CG1 4.23Å; I741-I745 HydrophobicContact CG1-CD1 3.76Å; I741-I745 HydrophobicContact CG1-CG1 4.34Å; I741-I745 WeakPolarHBondContact O-CG1 3.23Å; I741-I745 PolarHBondContact O-N 3.14Å; Q742-I745 PolarHBondContact O-N 2.8Å; I745-A747 PolarHBondContact O-N 3.15Å; I745-F748 PolarHBondContact O-N 3.08Å; I745-L749 HydrophobicContact CG2-CD1 3.78Å; I745-L749 HydrophobicContact CG2-CG 4.24Å; I745-L749 WeakPolarHBondContact O-CB 3.49Å; I745-L749 WeakPolarHBondContact O-CG 3.4Å; I745-L749 PolarHBondContact O-N 3.31Å
746N94.4Very high90Very high84 Ų8436.5 Ų36.545%0.44919%0.186SC..Hα-helixtrans-62-43.7-178.8-70.1-8.9000111.9Q742 P743 Q744 L749 Q750Q742-N746 PolarHBondContact NE2-OD1 3.39Å; Q742-N746 WeakPolarHBondContact O-CB 3.45Å; Q742-N746 PolarHBondContact O-N 3.23Å; Q742-N746 PolarHBondContact O-ND2 2.84Å; Q742-N746 PolarHBondContact O-OD1 2.95Å; P743-N746 PolarHBondContact O-N 2.7Å; Q744-N746 PolarHBondContact O-N 3.34Å; N746-L749 PolarHBondContact O-N 2.94Å; N746-Q750 WeakPolarHBondContact O-CB 3.17Å; N746-Q750 PolarHBondContact O-N 3.49Å
747A95.7Very high90.3Very high9 Ų934.4 Ų34.47%0.07419%0.185CC..Hα-helixtrans-62.6-45.4176.800000111.3L626 F629 Q630 P743 Q744 I745 Q750 G751L626-A747 HydrophobicContact CB-CB 4.33Å; L626-A747 HydrophobicContact CD2-CB 4.4Å; L626-A747 WeakPolarHBondContact O-CB 3.25Å; F629-A747 HydrophobicContact CB-CB 4.04Å; Q630-A747 VanDerWaalsContact CA-O 3.24Å; Q630-A747 WeakPolarHBondContact CA-O 3.37Å; Q630-A747 HydrophobicContact CB-CB 4.47Å; Q630-A747 WeakPolarHBondContact CB-O 3.25Å; P743-A747 WeakPolarHBondContact O-CB 3.41Å; P743-A747 PolarHBondContact O-N 2.91Å; Q744-A747 PolarHBondContact O-N 3.15Å; I745-A747 PolarHBondContact O-N 3.15Å; A747-Q750 WeakPolarHBondContact O-CB 3.18Å; A747-Q750 PolarHBondContact O-N 3.47Å; A747-G751 PolarHBondContact O-N 3.46Å
748F96.5Very high90.4Very high1 Ų137.2 Ų37.20%0.00420%0.203CC..Hα-helixtrans-58.8-49.4175.5-178.8-85.4000112F604 F629 A632 G633 L636 F654 I658 Q744 I745 Q750 G751 F752F604-F748 HydrophobicContact CZ-CD2 4.49Å; F629-F748 HydrophobicContact CB-CB 4.48Å; F629-F748 WeakPolarHBondContact O-CA 3.08Å; A632-F748 HydrophobicContact CB-CD2 4.25Å; A632-F748 HydrophobicContact CB-CE2 4.27Å; G633-F748 WeakPolarHBondContact CA-O 3.45Å; L636-F748 HydrophobicContact CB-CZ 4.43Å; L636-F748 HydrophobicContact CD2-CZ 4.1Å; F654-F748 HydrophobicContact CE1-CD1 4.47Å; F654-F748 HydrophobicContact CE1-CE1 4.18Å; F654-F748 HydrophobicContact CE1-CE2 4.37Å; F654-F748 HydrophobicContact CE1-CZ 4.12Å; F654-F748 AromaticContact CZ-CD1 3.87Å; F654-F748 HydrophobicContact CZ-CD1 3.87Å; F654-F748 HydrophobicContact CZ-CD2 4.14Å; F654-F748 HydrophobicContact CZ-CE1 4.04Å; F654-F748 HydrophobicContact CZ-CE2 4.28Å; F654-F748 AromaticContact CZ-CG 3.93Å; F654-F748 HydrophobicContact CZ-CG 3.93Å; F654-F748 HydrophobicContact CZ-CZ 4.24Å; I658-F748 HydrophobicContact CD1-CE1 3.82Å; I658-F748 HydrophobicContact CD1-CZ 4.39Å; I658-F748 HydrophobicContact CG1-CD1 4.47Å; I658-F748 HydrophobicContact CG1-CE1 3.99Å; Q744-F748 WeakPolarHBondContact O-CB 3.23Å; Q744-F748 PolarHBondContact O-N 3.24Å; I745-F748 PolarHBondContact O-N 3.08Å; F748-Q750 VanDerWaalsContact C-N 3.31Å; F748-Q750 PolarHBondContact O-N 2.95Å; F748-G751 PolarHBondContact O-N 3.28Å; F748-G751 VanDerWaalsContact O-N 3.1Å; F748-F752 HydrophobicContact CE1-CB 4.29Å; F748-F752 HydrophobicContact CE1-CD2 4.43Å; F748-F752 PolarHBondContact O-N 3.47Å
749L95.1Very high90.2Very high31 Ų3138.5 Ų38.516%0.16221%0.213CC..Hα-helixtrans-61.6-38.1179.4-75.1177000112.4I658 I745 N746 G751 F752 H753I658-L749 HydrophobicContact CB-CD2 4.32Å; I658-L749 HydrophobicContact CG1-CD2 4.33Å; I658-L749 HydrophobicContact CG2-CD2 4.27Å; I745-L749 HydrophobicContact CG2-CD1 3.78Å; I745-L749 HydrophobicContact CG2-CG 4.24Å; I745-L749 WeakPolarHBondContact O-CB 3.49Å; I745-L749 WeakPolarHBondContact O-CG 3.4Å; I745-L749 PolarHBondContact O-N 3.31Å; N746-L749 PolarHBondContact O-N 2.94Å; L749-G751 VanDerWaalsContact C-N 3.29Å; L749-G751 PolarHBondContact O-N 2.92Å; L749-F752 PolarHBondContact O-N 3.28Å; L749-H753 WeakPolarHBondContact O-CB 3.27Å; L749-H753 PolarHBondContact O-CD2 3.16Å; L749-H753 PolarHBondContact O-N 3.06Å
750Q94.6Very high90.2Very high119 Ų11934.8 Ų34.856%0.55620%0.201SC*.Hα-helixtrans-59.6-41.7174.6-174.7-179.47.500111.5N746 A747 F748 T754N746-Q750 WeakPolarHBondContact O-CB 3.17Å; N746-Q750 PolarHBondContact O-N 3.49Å; A747-Q750 WeakPolarHBondContact O-CB 3.18Å; A747-Q750 PolarHBondContact O-N 3.47Å; F748-Q750 VanDerWaalsContact C-N 3.31Å; F748-Q750 PolarHBondContact O-N 2.95Å; Q750-T754 PolarHBondContact O-N 2.91Å; Q750-T754 PolarHBondContact O-OG1 3.42Å
751G93.4Very high90.5Very high0 Ų032.4 Ų32.40%018%0.181CC..Hα-helixtrans-66.4-48.9174.600000112.8Q630 A747 F748 L749 H753 T754Q630-G751 WeakPolarHBondContact O-CA 3.48Å; A747-G751 PolarHBondContact O-N 3.46Å; F748-G751 PolarHBondContact O-N 3.28Å; F748-G751 VanDerWaalsContact O-N 3.1Å; L749-G751 VanDerWaalsContact C-N 3.29Å; L749-G751 PolarHBondContact O-N 2.92Å; G751-H753 PolarHBondContact O-N 3.22Å; G751-T754 VanDerWaalsContact O-CB 3.24Å; G751-T754 WeakPolarHBondContact O-CB 3.36Å; G751-T754 PolarHBondContact O-N 3.42Å; G751-T754 PolarHBondContact O-OG1 3.37Å
752F94.7Very high90.4Very high0 Ų035.3 Ų35.30%019%0.194CC..Hα-helixtrans-61.3-46.8-177.9-171.9-97.2000112.3G633 L636 L640 I658 F748 L749 T754 F755 I756 I761 L773G633-F752 VanDerWaalsContact O-CA 3.23Å; G633-F752 WeakPolarHBondContact O-CA 3.27Å; G633-F752 PolarHBondContact O-N 2.84Å; L636-F752 HydrophobicContact CB-CD2 4.2Å; L636-F752 HydrophobicContact CB-CE2 4.36Å; L640-F752 HydrophobicContact CD2-CZ 3.96Å; I658-F752 HydrophobicContact CG2-CD1 4.31Å; I658-F752 HydrophobicContact CG2-CE1 4.07Å; I658-F752 HydrophobicContact CG2-CZ 4.48Å; F748-F752 HydrophobicContact CE1-CB 4.29Å; F748-F752 HydrophobicContact CE1-CD2 4.43Å; F748-F752 PolarHBondContact O-N 3.47Å; L749-F752 PolarHBondContact O-N 3.28Å; F752-T754 PolarHBondContact O-N 3.5Å; F752-F755 PolarHBondContact O-N 3.09Å; F752-I756 HydrophobicContact CD1-CB 4.29Å; F752-I756 HydrophobicContact CE1-CB 3.89Å; F752-I756 HydrophobicContact CE1-CG1 4.29Å; F752-I756 HydrophobicContact CE1-CG2 3.98Å; F752-I756 HydrophobicContact CZ-CB 4.29Å; F752-I756 HydrophobicContact CZ-CG1 4.21Å; F752-I756 HydrophobicContact CZ-CG2 4.37Å; F752-I756 PolarHBondContact O-N 3.15Å; F752-I756 VanDerWaalsContact O-N 3.13Å; F752-I761 HydrophobicContact CE1-CD1 4.44Å; F752-I761 HydrophobicContact CE1-CG1 4.14Å; F752-I761 HydrophobicContact CZ-CD1 4.33Å; F752-I761 HydrophobicContact CZ-CG1 4.43Å; F752-L773 HydrophobicContact CE2-CD2 4.47Å
753H93.2Very high90.1Very high54 Ų5432.1 Ų32.125%0.2518%0.179CC..THydrogen-bonded Turntrans-75.7-3.9-178.3-65.6-50.6000115L749 G751 F755 I756 P758L749-H753 WeakPolarHBondContact O-CB 3.27Å; L749-H753 PolarHBondContact O-CD2 3.16Å; L749-H753 PolarHBondContact O-N 3.06Å; G751-H753 PolarHBondContact O-N 3.22Å; H753-F755 PolarHBondContact O-N 3.09Å; H753-I756 VanDerWaalsContact CA-O 3.27Å; H753-I756 WeakPolarHBondContact CA-O 3.39Å; H753-I756 PolarHBondContact ND1-O 2.93Å; H753-P758 HydrophobicContact CB-CG 4.27Å
754T90.6Very high89.9Confident36 Ų3628.8 Ų28.822%0.22116%0.157CC..THydrogen-bonded Turntrans-62.6-33.8167.7-62.50000111.3N563 K567 Q750 G751 F752N563-T754 HydrophobicContact CB-CG2 4.34Å; N563-T754 VanDerWaalsContact CG-CG2 3.49Å; N563-T754 VanDerWaalsContact ND2-CG2 3.29Å; N563-T754 WeakPolarHBondContact ND2-CG2 3.46Å; K567-T754 PolarHBondContact NZ-O 2.88Å; Q750-T754 PolarHBondContact O-N 2.91Å; Q750-T754 PolarHBondContact O-OG1 3.42Å; G751-T754 VanDerWaalsContact O-CB 3.24Å; G751-T754 WeakPolarHBondContact O-CB 3.36Å; G751-T754 PolarHBondContact O-N 3.42Å; G751-T754 PolarHBondContact O-OG1 3.37Å; F752-T754 PolarHBondContact O-N 3.5Å
755F89.1Confident89.6Confident3 Ų329 Ų291%0.01316%0.159CC..THydrogen-bonded Turntrans-106.8-34.7-178.7-61.1-75.6000112.8L566 K567 Q634 L638 F752 H753L566-F755 HydrophobicContact CB-CE1 4.05Å; L566-F755 HydrophobicContact CB-CZ 4.33Å; L566-F755 HydrophobicContact CD1-CZ 3.98Å; K567-F755 HydrophobicContact CG-CD1 4.03Å; K567-F755 HydrophobicContact CG-CE1 4.29Å; Q634-F755 HydrophobicContact CB-CE2 4.06Å; Q634-F755 HydrophobicContact CG-CE2 4.22Å; L638-F755 HydrophobicContact CB-CD2 4.28Å; L638-F755 HydrophobicContact CB-CE2 4.32Å; L638-F755 HydrophobicContact CD1-CD1 4Å; L638-F755 HydrophobicContact CD1-CE1 3.79Å; L638-F755 HydrophobicContact CD1-CG 4.49Å; L638-F755 HydrophobicContact CD1-CZ 4.09Å; F752-F755 PolarHBondContact O-N 3.09Å; H753-F755 PolarHBondContact O-N 3.09Å
756I90Very high89.2Confident0 Ų029.2 Ų29.20%016%0.16CC..SBendtrans-116.1110.8-171.9-51.6-60.5000110.9F519 L523 G637 L640 F752 H753 I761F519-I756 HydrophobicContact CE2-CG2 4.11Å; F519-I756 HydrophobicContact CZ-CD1 4.31Å; F519-I756 HydrophobicContact CZ-CG2 4Å; L523-I756 HydrophobicContact CD1-CD1 4.19Å; L523-I756 HydrophobicContact CD2-CD1 3.78Å; G637-I756 WeakPolarHBondContact O-CD1 3.47Å; L640-I756 HydrophobicContact CB-CD1 4.15Å; L640-I756 HydrophobicContact CB-CG1 4.41Å; L640-I756 HydrophobicContact CD2-CD1 4.08Å; L640-I756 HydrophobicContact CD2-CG1 4.05Å; L640-I756 HydrophobicContact CD2-CG2 4.3Å; L640-I756 HydrophobicContact CG-CD1 3.99Å; L640-I756 HydrophobicContact CG-CG1 4.41Å; F752-I756 HydrophobicContact CD1-CB 4.29Å; F752-I756 HydrophobicContact CE1-CB 3.89Å; F752-I756 HydrophobicContact CE1-CG1 4.29Å; F752-I756 HydrophobicContact CE1-CG2 3.98Å; F752-I756 HydrophobicContact CZ-CB 4.29Å; F752-I756 HydrophobicContact CZ-CG1 4.21Å; F752-I756 HydrophobicContact CZ-CG2 4.37Å; F752-I756 PolarHBondContact O-N 3.15Å; F752-I756 VanDerWaalsContact O-N 3.13Å; H753-I756 VanDerWaalsContact CA-O 3.27Å; H753-I756 WeakPolarHBondContact CA-O 3.39Å; H753-I756 PolarHBondContact ND1-O 2.93Å; I756-I761 HydrophobicContact CG2-CB 4.24Å; I756-I761 HydrophobicContact CG2-CD1 4.25Å
757P86.4Confident88.7Confident50 Ų5026.5 Ų26.533%0.32514%0.143SC..  trans-56.5134177.4-25.834.3000112.8S759 L760 I761P757-S759 VanDerWaalsContact C-N 3.25Å; P757-S759 PolarHBondContact O-N 3.39Å; P757-L760 HydrophobicContact CB-CB 4.41Å; P757-L760 HydrophobicContact CB-CD1 4.19Å; P757-L760 HydrophobicContact CB-CG 4.1Å; P757-L760 HydrophobicContact CG-CD1 3.86Å; P757-L760 HydrophobicContact CG-CG 4.34Å; P757-L760 PolarHBondContact O-N 3.24Å; P757-L760 VanDerWaalsContact O-N 3.11Å; P757-I761 PolarHBondContact O-N 3.13Å
758P84.4Confident88.4Confident63 Ų6327.3 Ų27.341%0.40915%0.145SC..Hα-helixtrans-56.2-36.2178.1-23.328.9000114H753 L760 I761 Q762H753-P758 HydrophobicContact CB-CG 4.27Å; P758-L760 VanDerWaalsContact C-N 3.3Å; P758-L760 PolarHBondContact O-N 3.47Å; P758-I761 WeakPolarHBondContact O-CG2 3.35Å; P758-I761 PolarHBondContact O-N 3.2Å; P758-Q762 VanDerWaalsContact O-CG 3.32Å; P758-Q762 WeakPolarHBondContact O-CG 3.32Å; P758-Q762 PolarHBondContact O-N 3.02Å
759S79.1Confident88.1Confident46 Ų4627.2 Ų27.232%0.32215%0.145SC..Hα-helixtrans-64.5-3417951.60000112.9M500 P757M500-S759 WeakPolarHBondContact CE-O 3.32Å; P757-S759 VanDerWaalsContact C-N 3.25Å; P757-S759 PolarHBondContact O-N 3.39Å
760L82.9Confident87.9Confident18 Ų1825.8 Ų25.89%0.09414%0.138CC..Hα-helixtrans-76.5-37.2-179.6-67.2-176.9000111.9W518 F519 L523 P757 P758 Q762 L763W518-L760 HydrophobicContact CH2-CD2 3.94Å; W518-L760 HydrophobicContact CZ3-CD2 3.57Å; F519-L760 HydrophobicContact CD2-CB 3.86Å; F519-L760 HydrophobicContact CE2-CB 3.81Å; L523-L760 HydrophobicContact CD1-CD1 4.3Å; P757-L760 HydrophobicContact CB-CB 4.41Å; P757-L760 HydrophobicContact CB-CD1 4.19Å; P757-L760 HydrophobicContact CB-CG 4.1Å; P757-L760 HydrophobicContact CG-CD1 3.86Å; P757-L760 HydrophobicContact CG-CG 4.34Å; P757-L760 PolarHBondContact O-N 3.24Å; P757-L760 VanDerWaalsContact O-N 3.11Å; P758-L760 VanDerWaalsContact C-N 3.3Å; P758-L760 PolarHBondContact O-N 3.47Å; L760-Q762 VanDerWaalsContact C-N 3.3Å; L760-Q762 PolarHBondContact O-N 2.93Å; L760-L763 WeakPolarHBondContact O-CB 3.48Å; L760-L763 WeakPolarHBondContact O-CD1 3.45Å; L760-L763 VanDerWaalsContact O-CG 3.25Å; L760-L763 WeakPolarHBondContact O-CG 3.37Å; L760-L763 PolarHBondContact O-N 3.37Å
761I87.9Confident87.7Confident1 Ų120.7 Ų20.71%0.00511%0.114CC..Hα-helixtrans-72.5-26.7-178.6-155.363.9000112.4F519 L640 L659 F752 I756 P757 P758 L763 F764 L769 L772F519-I761 HydrophobicContact CE2-CD1 4.39Å; L640-I761 HydrophobicContact CD2-CD1 3.94Å; L659-I761 HydrophobicContact CD2-CG1 4.2Å; L659-I761 HydrophobicContact CD2-CG2 4.42Å; L659-I761 VanDerWaalsContact CD2-O 3.25Å; L659-I761 WeakPolarHBondContact CD2-O 3.21Å; F752-I761 HydrophobicContact CE1-CD1 4.44Å; F752-I761 HydrophobicContact CE1-CG1 4.14Å; F752-I761 HydrophobicContact CZ-CD1 4.33Å; F752-I761 HydrophobicContact CZ-CG1 4.43Å; I756-I761 HydrophobicContact CG2-CB 4.24Å; I756-I761 HydrophobicContact CG2-CD1 4.25Å; P757-I761 PolarHBondContact O-N 3.13Å; P758-I761 WeakPolarHBondContact O-CG2 3.35Å; P758-I761 PolarHBondContact O-N 3.2Å; I761-L763 PolarHBondContact O-N 3.28Å; I761-L763 VanDerWaalsContact O-N 3.11Å; I761-F764 HydrophobicContact CD1-CD2 4.35Å; I761-F764 PolarHBondContact O-N 3.24Å; I761-L769 HydrophobicContact CD1-CD1 3.55Å; I761-L769 HydrophobicContact CG1-CD1 3.83Å; I761-L772 HydrophobicContact CD1-CD2 3.84Å
762Q84.6Confident87.6Confident75 Ų7521.2 Ų21.235%0.3512%0.117SC..THydrogen-bonded Turntrans-65-11.7177-77176.4-3.500114.4M504 K508 P758 L760 F764M504-Q762 HydrophobicContact CE-CB 4.24Å; K508-Q762 WeakPolarHBondContact CE-O 3.32Å; P758-Q762 VanDerWaalsContact O-CG 3.32Å; P758-Q762 WeakPolarHBondContact O-CG 3.32Å; P758-Q762 PolarHBondContact O-N 3.02Å; L760-Q762 VanDerWaalsContact C-N 3.3Å; L760-Q762 PolarHBondContact O-N 2.93Å; Q762-F764 PolarHBondContact O-N 3.01Å
763L83.1Confident87.3Confident2 Ų221.3 Ų21.31%0.0112%0.118CC..THydrogen-bonded Turntrans-62.6-20.9172.7-63.9176.4000112.7L494 M500 I507 R515 W518 L760 I761L494-L763 HydrophobicContact CD2-CD2 3.87Å; M500-L763 HydrophobicContact SD-CD2 4.22Å; I507-L763 HydrophobicContact CG2-CD2 3.64Å; R515-L763 PolarHBondContact NH1-O 2.92Å; W518-L763 HydrophobicContact CE3-CD1 3.72Å; W518-L763 HydrophobicContact CZ3-CD1 3.59Å; L760-L763 WeakPolarHBondContact O-CB 3.48Å; L760-L763 WeakPolarHBondContact O-CD1 3.45Å; L760-L763 VanDerWaalsContact O-CG 3.25Å; L760-L763 WeakPolarHBondContact O-CG 3.37Å; L760-L763 PolarHBondContact O-N 3.37Å; I761-L763 PolarHBondContact O-N 3.28Å; I761-L763 VanDerWaalsContact O-N 3.11Å
764F87.1Confident87.1Confident0 Ų019.5 Ų19.50%011%0.111CC..SBendtrans-106.3157.9-176.3-55-75.3000111.5K508 F512 R515 F519 I761 Q762 E768 L772K508-F764 PolarHBondContact NZ-O 3.31Å; F512-F764 AromaticContact CD2-CD1 3.96Å; F512-F764 HydrophobicContact CD2-CD1 3.96Å; F512-F764 HydrophobicContact CD2-CE1 4.04Å; F512-F764 AromaticContact CE2-CD1 3.79Å; F512-F764 HydrophobicContact CE2-CD1 3.79Å; F512-F764 AromaticContact CE2-CE1 3.87Å; F512-F764 HydrophobicContact CE2-CE1 3.87Å; R515-F764 HydrophobicContact CB-CE1 3.88Å; R515-F764 HydrophobicContact CB-CZ 4.31Å; F519-F764 HydrophobicContact CB-CE2 4.13Å; F519-F764 HydrophobicContact CB-CZ 3.96Å; F519-F764 AromaticContact CD2-CE2 3.83Å; F519-F764 HydrophobicContact CD2-CE2 3.83Å; F519-F764 HydrophobicContact CE2-CE2 4.44Å; F519-F764 AromaticContact CG-CE2 3.99Å; F519-F764 HydrophobicContact CG-CE2 3.99Å; F519-F764 HydrophobicContact CG-CZ 4.23Å; I761-F764 HydrophobicContact CD1-CD2 4.35Å; I761-F764 PolarHBondContact O-N 3.24Å; Q762-F764 PolarHBondContact O-N 3.01Å; F764-E768 WeakPolarHBondContact CA-OE2 3.16Å; F764-E768 HydrophobicContact CB-CB 3.95Å; F764-E768 HydrophobicContact CD1-CB 4.14Å; F764-E768 HydrophobicContact CG-CB 4.49Å; F764-L772 HydrophobicContact CD2-CD2 3.8Å; F764-L772 HydrophobicContact CE2-CD2 3.67Å; F764-L772 HydrophobicContact CG-CD2 4.4Å; F764-L772 HydrophobicContact CZ-CD2 4.17Å
765D85.4Confident86.8Confident12 Ų1218.4 Ų18.46%0.06411%0.107CC..  trans-93.1179.8165.271.128.5000112L659 Y767 E768 L769L659-D765 WeakPolarHBondContact CD1-O 3.12Å; D765-Y767 PolarHBondContact O-N 3.45Å; D765-Y767 WeakPolarHBondContact OD1-CA 3.31Å; D765-Y767 WeakPolarHBondContact OD1-CB 3.48Å; D765-Y767 PolarHBondContact OD1-N 3.09Å; D765-E768 PolarHBondContact N-OE2 3.26Å; D765-E768 VanDerWaalsContact N-OE2 3.12Å; D765-E768 PolarHBondContact O-N 2.77Å; D765-E768 WeakPolarHBondContact OD1-CB 3.4Å; D765-E768 VanDerWaalsContact OD1-CG 3.3Å; D765-E768 WeakPolarHBondContact OD1-CG 3.4Å; D765-E768 PolarHBondContact OD1-N 3.31Å; D765-L769 WeakPolarHBondContact O-CB 3.43Å; D765-L769 PolarHBondContact O-N 3.13Å
766E85Confident86.6Confident9 Ų922 Ų224%0.04212%0.124CC..Hα-helixtrans-68.9-17.8-177.667.7-89.9-149.400114.5R652 K656 L659R652-E766 PolarHBondContact NH1-O 3.09Å; R652-E766 VanDerWaalsContact NH1-O 3.08Å; K656-E766 WeakPolarHBondContact CE-OE1 3.36Å; K656-E766 HydrophobicContact CG-CB 3.99Å; K656-E766 HydrophobicContact CG-CG 4.18Å; K656-E766 IonicContact NZ-OE1 3.55Å; L659-E766 HydrophobicContact CD1-CB 4.24Å
767Y84.6Confident86.4Confident28 Ų2823.3 Ų23.311%0.1113%0.133CC..Hα-helixtrans-84-43.9175.6-65.9-95.1000109.9D765 E770 L771 L818 Q821 G890 S891D765-Y767 PolarHBondContact O-N 3.45Å; D765-Y767 WeakPolarHBondContact OD1-CA 3.31Å; D765-Y767 WeakPolarHBondContact OD1-CB 3.48Å; D765-Y767 PolarHBondContact OD1-N 3.09Å; Y767-E770 WeakPolarHBondContact O-CB 3.42Å; Y767-E770 PolarHBondContact O-N 2.71Å; Y767-L771 WeakPolarHBondContact O-CG 3.23Å; Y767-L771 PolarHBondContact O-N 2.67Å; Y767-L818 HydrophobicContact CD1-CD2 4.33Å; Y767-L818 HydrophobicContact CG-CD2 4.28Å; Y767-Q821 HydrophobicContact CD1-CB 3.88Å; Y767-Q821 HydrophobicContact CD1-CG 4.39Å; Y767-Q821 HydrophobicContact CE1-CB 4.11Å; Y767-Q821 PolarHBondContact O-NE2 3.01Å; Y767-G890 PolarHBondContact OH-O 3.17Å; Y767-S891 VanDerWaalsContact CE2-CA 3.44Å
768E88.4Confident86.4Confident25 Ų2529.5 Ų29.512%0.11716%0.158CC..Hα-helixtrans-70-35.5179.1-69.5175.5150.700112.6F512 R515 F764 D765 E770 L771 L772F512-E768 HydrophobicContact CD2-CB 3.77Å; F512-E768 HydrophobicContact CD2-CG 3.66Å; F512-E768 HydrophobicContact CE2-CB 3.65Å; F512-E768 HydrophobicContact CE2-CG 4.05Å; F512-E768 HydrophobicContact CG-CG 4.45Å; R515-E768 IonicContact CZ-OE1 2.81Å; R515-E768 IonicContact CZ-OE2 3.73Å; R515-E768 IonicContact NH1-OE1 2.73Å; R515-E768 IonicContact NH1-OE2 2.97Å; R515-E768 PolarHBondContact NH1-OE2 3.4Å; R515-E768 IonicContact NH2-OE1 3.33Å; R515-E768 PolarHBondContact NH2-OE1 2.85Å; R515-E768 IonicContact NH2-OE2 2.82Å; R515-E768 PolarHBondContact NH2-OE2 3.36Å; F764-E768 WeakPolarHBondContact CA-OE2 3.16Å; F764-E768 HydrophobicContact CB-CB 3.95Å; F764-E768 HydrophobicContact CD1-CB 4.14Å; F764-E768 HydrophobicContact CG-CB 4.49Å; D765-E768 PolarHBondContact N-OE2 3.26Å; D765-E768 VanDerWaalsContact N-OE2 3.12Å; D765-E768 PolarHBondContact O-N 2.77Å; D765-E768 WeakPolarHBondContact OD1-CB 3.4Å; D765-E768 VanDerWaalsContact OD1-CG 3.3Å; D765-E768 WeakPolarHBondContact OD1-CG 3.4Å; D765-E768 PolarHBondContact OD1-N 3.31Å; E768-E770 VanDerWaalsContact C-N 3.28Å; E768-E770 PolarHBondContact O-N 2.9Å; E768-L771 PolarHBondContact O-N 3.25Å; E768-L771 VanDerWaalsContact O-N 3.15Å; E768-L772 VanDerWaalsContact O-CB 3.32Å; E768-L772 WeakPolarHBondContact O-CB 3.47Å; E768-L772 PolarHBondContact O-N 3.23Å
769L90.9Very high86.6Confident0 Ų027 Ų270%014%0.141CC..Hα-helixtrans-62.5-37174.9-179.958.3000111.9Y655 I658 L659 I761 D765 L771 L772 L773Y655-L769 HydrophobicContact CD1-CB 4.34Å; Y655-L769 HydrophobicContact CD1-CD2 3.86Å; Y655-L769 HydrophobicContact CD1-CG 3.87Å; Y655-L769 HydrophobicContact CE1-CG 4.46Å; I658-L769 HydrophobicContact CB-CD2 3.88Å; I658-L769 HydrophobicContact CD1-CD2 4.38Å; I658-L769 HydrophobicContact CG2-CD2 3.72Å; L659-L769 HydrophobicContact CD1-CB 4.43Å; L659-L769 HydrophobicContact CD1-CD2 4.22Å; L659-L769 HydrophobicContact CD2-CD2 3.95Å; L659-L769 HydrophobicContact CG-CD2 3.8Å; I761-L769 HydrophobicContact CD1-CD1 3.55Å; I761-L769 HydrophobicContact CG1-CD1 3.83Å; D765-L769 WeakPolarHBondContact O-CB 3.43Å; D765-L769 PolarHBondContact O-N 3.13Å; L769-L771 VanDerWaalsContact C-N 3.35Å; L769-L772 HydrophobicContact CD1-CD2 4.45Å; L769-L772 PolarHBondContact O-N 2.96Å; L769-L773 HydrophobicContact CD1-CD1 4.23Å; L769-L773 HydrophobicContact CD1-CG 4.45Å; L769-L773 HydrophobicContact CG-CD1 4.35Å; L769-L773 WeakPolarHBondContact O-CG 3.44Å; L769-L773 PolarHBondContact O-N 2.98Å
770E91.1Very high87.3Confident1 Ų129.2 Ų29.21%0.00515%0.149CC..Hα-helixtrans-60.9-45.8172.6179.2-171.5165.600110.9Y649 R652 Y655 Y767 E768 L773 S774 Q821 S826 S827Y649-E770 HydrophobicContact CD1-CG 4.24Å; Y649-E770 WeakPolarHBondContact CD1-OE1 3.23Å; R652-E770 IonicContact CZ-OE2 2.87Å; R652-E770 IonicContact NH1-OE2 2.83Å; R652-E770 PolarHBondContact NH1-OE2 3Å; R652-E770 IonicContact NH2-OE2 3.78Å; R652-E770 PolarHBondContact NH2-OE2 3.4Å; Y655-E770 HydrophobicContact CD2-CB 4.44Å; Y655-E770 HydrophobicContact CE1-CB 4.25Å; Y655-E770 HydrophobicContact CE2-CB 3.82Å; Y655-E770 HydrophobicContact CE2-CG 4.09Å; Y767-E770 WeakPolarHBondContact O-CB 3.42Å; Y767-E770 PolarHBondContact O-N 2.71Å; E768-E770 VanDerWaalsContact C-N 3.28Å; E768-E770 PolarHBondContact O-N 2.9Å; E770-L773 PolarHBondContact O-N 3.27Å; E770-S774 WeakPolarHBondContact O-CB 3.32Å; E770-S774 PolarHBondContact O-N 3.02Å; E770-S774 PolarHBondContact O-OG 3.16Å; E770-Q821 PolarHBondContact OE2-NE2 2.93Å; E770-S826 PolarHBondContact OE1-OG 3.09Å; E770-S827 WeakPolarHBondContact OE1-CB 3.33Å; E770-S827 PolarHBondContact OE1-N 2.89Å; E770-S827 PolarHBondContact OE1-OG 2.94Å
771L90Very high87.8Confident12 Ų1228.9 Ų28.96%0.06315%0.148CC..Hα-helixtrans-68.7-34.5179.9-58.7-178.7000112.4F512 Y767 E768 L769 L773 G775 V817F512-L771 HydrophobicContact CE1-CB 4.23Å; F512-L771 HydrophobicContact CZ-CB 3.91Å; Y767-L771 WeakPolarHBondContact O-CG 3.23Å; Y767-L771 PolarHBondContact O-N 2.67Å; E768-L771 PolarHBondContact O-N 3.25Å; E768-L771 VanDerWaalsContact O-N 3.15Å; L769-L771 VanDerWaalsContact C-N 3.35Å; L771-L773 VanDerWaalsContact C-N 3.28Å; L771-L773 PolarHBondContact O-N 2.92Å; L771-G775 CarbonylContact O-C 3.56Å; L771-G775 WeakPolarHBondContact O-CA 3.37Å; L771-G775 PolarHBondContact O-N 2.69Å; L771-V817 HydrophobicContact CD1-CG1 4.04Å; L771-V817 HydrophobicContact CD2-CG1 3.52Å; L771-V817 HydrophobicContact CG-CG1 4.38Å
772L90.3Very high88.1Confident10 Ų1033 Ų335%0.05217%0.167CC..Hα-helixtrans-65.2-34.5177.2-174.765.3000111.4F512 F519 Y520 L640 I761 F764 E768 L769F512-L772 HydrophobicContact CZ-CB 4.46Å; F519-L772 HydrophobicContact CE1-CD2 4.47Å; Y520-L772 HydrophobicContact CE2-CD1 4.32Å; L640-L772 HydrophobicContact CD1-CD1 4.03Å; L640-L772 HydrophobicContact CD1-CD2 3.95Å; L640-L772 HydrophobicContact CD1-CG 3.56Å; L640-L772 HydrophobicContact CD2-CD2 4.03Å; L640-L772 HydrophobicContact CD2-CG 4.46Å; I761-L772 HydrophobicContact CD1-CD2 3.84Å; F764-L772 HydrophobicContact CD2-CD2 3.8Å; F764-L772 HydrophobicContact CE2-CD2 3.67Å; F764-L772 HydrophobicContact CG-CD2 4.4Å; F764-L772 HydrophobicContact CZ-CD2 4.17Å; E768-L772 VanDerWaalsContact O-CB 3.32Å; E768-L772 WeakPolarHBondContact O-CB 3.47Å; E768-L772 PolarHBondContact O-N 3.23Å; L769-L772 HydrophobicContact CD1-CD2 4.45Å; L769-L772 PolarHBondContact O-N 2.96Å
773L90.3Very high88.6Confident3 Ų330.6 Ų30.62%0.01616%0.156CC..Hα-helixtrans-85.4-42.6177.9-71.9168.8000113.2L636 L640 L645 V646 Y655 F752 L769 E770 L771L636-L773 HydrophobicContact CD2-CD1 4.45Å; L640-L773 HydrophobicContact CB-CD2 4.13Å; L640-L773 HydrophobicContact CD2-CD2 4.39Å; L645-L773 WeakPolarHBondContact CA-O 3.3Å; V646-L773 HydrophobicContact CG2-CB 3.98Å; V646-L773 WeakPolarHBondContact CG2-O 3.36Å; V646-L773 PolarHBondContact N-O 3.5Å; Y655-L773 HydrophobicContact CE1-CD1 4.07Å; F752-L773 HydrophobicContact CE2-CD2 4.47Å; L769-L773 HydrophobicContact CD1-CD1 4.23Å; L769-L773 HydrophobicContact CD1-CG 4.45Å; L769-L773 HydrophobicContact CG-CD1 4.35Å; L769-L773 WeakPolarHBondContact O-CG 3.44Å; L769-L773 PolarHBondContact O-N 2.98Å; E770-L773 PolarHBondContact O-N 3.27Å; L771-L773 VanDerWaalsContact C-N 3.28Å; L771-L773 PolarHBondContact O-N 2.92Å
774S87.2Confident89.1Confident15 Ų1530.5 Ų30.511%0.10516%0.156CC..Hα-helixtrans-101.3-13-168.6-380000113.4V646 I648 E770V646-S774 WeakPolarHBondContact O-CA 3.12Å; I648-S774 PolarHBondContact O-OG 2.8Å; E770-S774 WeakPolarHBondContact O-CB 3.32Å; E770-S774 PolarHBondContact O-N 3.02Å; E770-S774 PolarHBondContact O-OG 3.16Å
775G85.8Confident89.4Confident14 Ų1432 Ų3214%0.14417%0.166CC..  trans88.4161-176.400000113L771 P777L771-G775 CarbonylContact O-C 3.56Å; L771-G775 WeakPolarHBondContact O-CA 3.37Å; L771-G775 PolarHBondContact O-N 2.69Å; G775-P777 WeakPolarHBondContact O-CD 3.45Å
776M83.9Confident89.8Confident77 Ų7739.6 Ų39.638%0.37919%0.194SC..  trans-84.3114.2174.4-172.9179-64.800109.5F512 Q813 E814 V817F512-M776 HydrophobicContact CD1-CE 3.93Å; F512-M776 HydrophobicContact CE1-CE 4.11Å; M776-Q813 HydrophobicContact CG-CG 4.33Å; M776-Q813 HydrophobicContact SD-CB 4.32Å; M776-Q813 HydrophobicContact SD-CG 3.96Å; M776-E814 HydrophobicContact CE-CG 3.45Å; M776-E814 VanDerWaalsContact CE-CG 3.45Å; M776-E814 HydrophobicContact SD-CG 4.16Å; M776-V817 HydrophobicContact CG-CG2 4.33Å
777P85.9Confident90.2Very high29 Ų2940.5 Ų40.519%0.18820%0.199CC..  trans-75.4150.1-179.630.9-34.2000110.8G775 Q813 V817 S827 V829G775-P777 WeakPolarHBondContact O-CD 3.45Å; P777-Q813 PolarHBondContact O-NE2 2.62Å; P777-V817 HydrophobicContact CG-CG1 4.48Å; P777-V817 HydrophobicContact CG-CG2 3.92Å; P777-S827 WeakPolarHBondContact CG-O 3.45Å; P777-V829 HydrophobicContact CB-CG2 4.19Å
778E85.5Confident90.7Very high180 Ų18039.9 Ų39.984%0.84120%0.198SC*.  trans-82.7127.9167-67.5-172.4174.300109.7
779I90.6Very high91Very high11 Ų1142.4 Ų42.46%0.05621%0.21CC..  trans-109.3112.3-175.9-66.5174.5000108.6V781 W784 R816 V817 L820 V829 F834I779-V781 HydrophobicContact CG2-CG2 4.43Å; I779-V781 PolarHBondContact O-N 3.11Å; I779-W784 HydrophobicContact CG2-CE3 3.68Å; I779-W784 HydrophobicContact CG2-CZ3 4.04Å; I779-R816 HydrophobicContact CD1-CB 3.93Å; I779-V817 HydrophobicContact CD1-CB 4.32Å; I779-V817 HydrophobicContact CD1-CG2 3.65Å; I779-V817 HydrophobicContact CG1-CG2 4.4Å; I779-L820 HydrophobicContact CD1-CB 4.24Å; I779-L820 HydrophobicContact CD1-CD2 4.04Å; I779-V829 HydrophobicContact CG1-CG2 4.34Å; I779-F834 HydrophobicContact CG2-CE2 4.08Å; I779-F834 HydrophobicContact CG2-CZ 3.99Å
780D92.3Very high91.1Very high91 Ų9144.6 Ų44.649%0.48722%0.219SC..  trans-77.1100.4167.5-174.8-15.5000109.5E782 D783 W784D780-E782 VanDerWaalsContact C-N 3.25Å; D780-E782 PolarHBondContact O-N 3.42Å; D780-E782 PolarHBondContact OD1-N 3.03Å; D780-D783 HydrophobicContact CB-CB 3.93Å; D780-D783 PolarHBondContact O-N 3.25Å; D780-D783 PolarHBondContact OD1-N 3.34Å; D780-W784 PolarHBondContact O-N 3.07Å
781V93.5Very high90.9Very high11 Ų1147.1 Ų47.17%0.06723%0.234CC..Hα-helixtrans-64.5-30.3-179.8-178.80000111.8I779 W784 C785 W805 V808 R809I779-V781 HydrophobicContact CG2-CG2 4.43Å; I779-V781 PolarHBondContact O-N 3.11Å; V781-W784 PolarHBondContact O-N 3.14Å; V781-C785 VanDerWaalsContact O-CB 3.26Å; V781-C785 WeakPolarHBondContact O-CB 3.47Å; V781-C785 PolarHBondContact O-N 3.34Å; V781-W805 HydrophobicContact CG1-CE3 4.01Å; V781-W805 HydrophobicContact CG1-CZ3 4.14Å; V781-V808 HydrophobicContact CG1-CG1 3.84Å; V781-V808 HydrophobicContact CG2-CG1 4.32Å; V781-R809 HydrophobicContact CG1-CG 3.85Å
782E94.3Very high90.4Very high89 Ų8951.1 Ų51.142%0.41626%0.263SS..Hα-helixtrans-76.6-33.8179.6-59.3-53.5144.400111.3D780 R786 R809D780-E782 VanDerWaalsContact C-N 3.25Å; D780-E782 PolarHBondContact O-N 3.42Å; D780-E782 PolarHBondContact OD1-N 3.03Å; E782-R786 WeakPolarHBondContact O-CB 3.43Å; E782-R786 WeakPolarHBondContact O-CG 3.43Å; E782-R786 PolarHBondContact O-N 2.75Å; E782-R786 VanDerWaalsContact O-N 3.09Å; E782-R786 PolarHBondContact O-NE 3.42Å; E782-R786 VanDerWaalsContact O-NE 3.09Å; E782-R809 IonicContact OE1-CZ 3.46Å; E782-R809 IonicContact OE1-NE 2.68Å; E782-R809 PolarHBondContact OE1-NE 3.45Å; E782-R809 IonicContact OE1-NH2 3.38Å; E782-R809 PolarHBondContact OE1-NH2 2.86Å; E782-R809 IonicContact OE2-CZ 3.51Å; E782-R809 IonicContact OE2-NE 2.62Å; E782-R809 IonicContact OE2-NH2 3.48Å; E782-R809 PolarHBondContact OE2-NH2 3.28Å
783D94.7Very high89.8Confident23 Ų2353.8 Ų53.812%0.12329%0.293CS..Hα-helixtrans-65.3-43168.4-168.559.1000112.3D780 R786 N787 G833 F834D780-D783 HydrophobicContact CB-CB 3.93Å; D780-D783 PolarHBondContact O-N 3.25Å; D780-D783 PolarHBondContact OD1-N 3.34Å; D783-R786 VanDerWaalsContact CA-NH2 3.3Å; D783-R786 PolarHBondContact O-N 2.92Å; D783-R786 IonicContact OD1-CZ 3.08Å; D783-R786 IonicContact OD1-NH1 3.82Å; D783-R786 IonicContact OD1-NH2 2.7Å; D783-R786 PolarHBondContact OD1-NH2 2.81Å; D783-N787 PolarHBondContact O-N 2.61Å; D783-N787 PolarHBondContact O-ND2 2.82Å; D783-N787 PolarHBondContact OD1-ND2 3.1Å; D783-N787 VanDerWaalsContact OD1-ND2 3.13Å; D783-G833 WeakPolarHBondContact OD2-CA 3.36Å; D783-F834 HydrophobicContact CB-CD2 4.43Å; D783-F834 PolarHBondContact OD2-N 2.79Å
784W94.2Very high89.9Confident1 Ų154.5 Ų54.50%0.00430%0.295CS..Hα-helixtrans-60.3-49.6176.5-163.1-7.1000111.6I779 D780 V781 R786 N787 T788 W805 L819 L820 F834 F846I779-W784 HydrophobicContact CG2-CE3 3.68Å; I779-W784 HydrophobicContact CG2-CZ3 4.04Å; D780-W784 PolarHBondContact O-N 3.07Å; V781-W784 PolarHBondContact O-N 3.14Å; W784-R786 VanDerWaalsContact C-N 3.33Å; W784-R786 PolarHBondContact O-N 2.9Å; W784-N787 CarbonylContact O-C 3.6Å; W784-N787 PolarHBondContact O-N 3.43Å; W784-N787 VanDerWaalsContact O-N 3.16Å; W784-T788 PolarHBondContact O-N 2.91Å; W784-T788 PolarHBondContact O-OG1 3.25Å; W784-W805 HydrophobicContact CB-CH2 4.21Å; W784-W805 HydrophobicContact CB-CZ3 4.31Å; W784-W805 AromaticContact CD1-CH2 3.91Å; W784-W805 HydrophobicContact CD2-CH2 4.19Å; W784-W805 HydrophobicContact CD2-CZ3 4.38Å; W784-W805 AromaticContact CG-CH2 3.84Å; W784-W805 HydrophobicContact CG-CH2 3.84Å; W784-W805 HydrophobicContact CG-CZ3 4.22Å; W784-L819 HydrophobicContact CH2-CB 4.46Å; W784-L819 HydrophobicContact CH2-CD2 4.24Å; W784-L819 HydrophobicContact CH2-CG 4Å; W784-L820 HydrophobicContact CH2-CB 3.82Å; W784-L820 HydrophobicContact CH2-CD1 3.93Å; W784-L820 HydrophobicContact CH2-CG 4.48Å; W784-L820 HydrophobicContact CZ2-CD1 3.88Å; W784-L820 HydrophobicContact CZ3-CB 4.29Å; W784-F834 HydrophobicContact CB-CD1 4.22Å; W784-F834 HydrophobicContact CB-CD2 3.56Å; W784-F834 HydrophobicContact CB-CE1 4.28Å; W784-F834 HydrophobicContact CB-CE2 3.63Å; W784-F834 HydrophobicContact CB-CG 3.87Å; W784-F834 HydrophobicContact CB-CZ 4Å; W784-F834 AromaticContact CD1-CD1 3.6Å; W784-F834 AromaticContact CD1-CE1 3.86Å; W784-F834 AromaticContact CD1-CG 3.93Å; W784-F834 HydrophobicContact CD2-CD1 4.15Å; W784-F834 AromaticContact CD2-CE1 3.6Å; W784-F834 HydrophobicContact CD2-CE1 3.6Å; W784-F834 HydrophobicContact CD2-CE2 4.2Å; W784-F834 AromaticContact CD2-CZ 3.63Å; W784-F834 HydrophobicContact CD2-CZ 3.63Å; W784-F834 AromaticContact CE2-CE1 3.79Å; W784-F834 HydrophobicContact CE3-CE1 4.11Å; W784-F834 HydrophobicContact CE3-CE2 4.36Å; W784-F834 AromaticContact CE3-CZ 3.74Å; W784-F834 HydrophobicContact CE3-CZ 3.74Å; W784-F834 AromaticContact CG-CD1 3.74Å; W784-F834 HydrophobicContact CG-CD1 3.74Å; W784-F834 AromaticContact CG-CD2 3.99Å; W784-F834 HydrophobicContact CG-CD2 3.99Å; W784-F834 AromaticContact CG-CE1 3.68Å; W784-F834 HydrophobicContact CG-CE1 3.68Å; W784-F834 AromaticContact CG-CE2 3.93Å; W784-F834 HydrophobicContact CG-CE2 3.93Å; W784-F834 AromaticContact CG-CG 3.89Å; W784-F834 HydrophobicContact CG-CG 3.89Å; W784-F834 AromaticContact CG-CZ 3.77Å; W784-F834 HydrophobicContact CG-CZ 3.77Å; W784-F834 HydrophobicContact CZ2-CE1 4.44Å; W784-F834 HydrophobicContact CZ3-CZ 4.43Å; W784-F834 AromaticContact NE1-CD1 3.94Å; W784-F834 AromaticContact NE1-CE1 3.93Å; W784-F846 AromaticContact CD1-CD1 3.98Å; W784-F846 HydrophobicContact CZ2-CD2 4.12Å; W784-F846 AromaticContact CZ2-CE2 3.91Å; W784-F846 HydrophobicContact CZ2-CE2 3.91Å; W784-F846 HydrophobicContact CZ2-CZ 4.28Å; W784-F846 AromaticContact NE1-CD1 3.37Å; W784-F846 AromaticContact NE1-CD2 3.61Å; W784-F846 AromaticContact NE1-CE1 3.86Å; W784-F846 AromaticContact NE1-CG 3.24Å
785C94Very high90Very high31 Ų3158 Ų5821%0.20931%0.313CS..Hα-helixtrans-60.2-40.6179.2-174.80000112.2V781 N787 T788 W805V781-C785 VanDerWaalsContact O-CB 3.26Å; V781-C785 WeakPolarHBondContact O-CB 3.47Å; V781-C785 PolarHBondContact O-N 3.34Å; C785-N787 VanDerWaalsContact C-N 3.28Å; C785-N787 PolarHBondContact O-N 2.98Å; C785-T788 PolarHBondContact O-N 3.01Å; C785-W805 HydrophobicContact CB-CD2 3.96Å; C785-W805 HydrophobicContact CB-CE3 3.98Å; C785-W805 HydrophobicContact CB-CH2 4.24Å; C785-W805 HydrophobicContact CB-CZ2 4.21Å; C785-W805 HydrophobicContact CB-CZ3 4.12Å
786R93.4Very high90.1Very high171 Ų17160.3 Ų60.365%0.64533%0.325SS*.Hα-helixtrans-66.2-29178.5-78.7-179.2-65.6130.40.3113.3E782 D783 W784E782-R786 WeakPolarHBondContact O-CB 3.43Å; E782-R786 WeakPolarHBondContact O-CG 3.43Å; E782-R786 PolarHBondContact O-N 2.75Å; E782-R786 VanDerWaalsContact O-N 3.09Å; E782-R786 PolarHBondContact O-NE 3.42Å; E782-R786 VanDerWaalsContact O-NE 3.09Å; D783-R786 VanDerWaalsContact CA-NH2 3.3Å; D783-R786 PolarHBondContact O-N 2.92Å; D783-R786 IonicContact OD1-CZ 3.08Å; D783-R786 IonicContact OD1-NH1 3.82Å; D783-R786 IonicContact OD1-NH2 2.7Å; D783-R786 PolarHBondContact OD1-NH2 2.81Å; W784-R786 VanDerWaalsContact C-N 3.33Å; W784-R786 PolarHBondContact O-N 2.9Å
787N93.6Very high90.3Very high29 Ų2963.2 Ų63.216%0.15534%0.338CS..THydrogen-bonded Turntrans-102.622.1-177.3-65.7-69.8000112.9D783 W784 C785 F834 A835 K845D783-N787 PolarHBondContact O-N 2.61Å; D783-N787 PolarHBondContact O-ND2 2.82Å; D783-N787 PolarHBondContact OD1-ND2 3.1Å; D783-N787 VanDerWaalsContact OD1-ND2 3.13Å; W784-N787 CarbonylContact O-C 3.6Å; W784-N787 PolarHBondContact O-N 3.43Å; W784-N787 VanDerWaalsContact O-N 3.16Å; C785-N787 VanDerWaalsContact C-N 3.28Å; C785-N787 PolarHBondContact O-N 2.98Å; N787-F834 HydrophobicContact CB-CB 4Å; N787-A835 WeakPolarHBondContact OD1-CB 3.43Å; N787-K845 WeakPolarHBondContact O-CD 3.43Å
788T94.7Very high90.6Very high14 Ų1464.4 Ų64.49%0.08634%0.343CS..EExtended strand (participates in β ladder)trans-96.1136.7178.8-61.50000112.1W784 C785 Y790 W805 F846 I848W784-T788 PolarHBondContact O-N 2.91Å; W784-T788 PolarHBondContact O-OG1 3.25Å; C785-T788 PolarHBondContact O-N 3.01Å; T788-Y790 HydrophobicContact CG2-CD1 4.45Å; T788-Y790 HydrophobicContact CG2-CE1 3.85Å; T788-Y790 HydrophobicContact CG2-CE2 4.11Å; T788-W805 HydrophobicContact CG2-CZ2 4.09Å; T788-W805 WeakPolarHBondContact OG1-CZ2 3.38Å; T788-F846 CarbonylContact C-O 3.48Å; T788-F846 WeakPolarHBondContact CA-O 3.49Å; T788-F846 HydrophobicContact CG2-CD1 3.55Å; T788-F846 HydrophobicContact CG2-CE1 3.88Å; T788-F846 WeakPolarHBondContact OG1-CD1 3.41Å; T788-I848 HydrophobicContact CG2-CD1 4.22Å; T788-I848 HydrophobicContact CG2-CG1 3.99Å
789E93.8Very high90.9Very high78 Ų7859 Ų5936%0.36432%0.324SS..EExtended strand (participates in β ladder)trans-104144.1172.9-65.3-178.6178.300110.9K845 F846 T847 I848E789-K845 HydrophobicContact CG-CB 4.23Å; E789-K845 HydrophobicContact CG-CD 4.15Å; E789-K845 WeakPolarHBondContact OE1-CD 3.39Å; E789-K845 WeakPolarHBondContact OE1-CE 3.2Å; E789-K845 IonicContact OE1-NZ 2.77Å; E789-K845 PolarHBondContact OE1-NZ 2.96Å; E789-F846 PolarHBondContact N-O 3.47Å; E789-T847 CarbonylContact O-C 3.19Å; E789-T847 VanDerWaalsContact O-CA 3.24Å; E789-T847 WeakPolarHBondContact O-CA 3.33Å; E789-I848 PolarHBondContact O-N 3.41Å
790Y93.1Very high91Very high47 Ų4759.3 Ų59.318%0.18433%0.326CS..EExtended strand (participates in β ladder)trans-117.1131.6-178.7-55.9-85.3000109.5T788 Y794 P796 I801 W805 I848T788-Y790 HydrophobicContact CG2-CD1 4.45Å; T788-Y790 HydrophobicContact CG2-CE1 3.85Å; T788-Y790 HydrophobicContact CG2-CE2 4.11Å; Y790-Y794 VanDerWaalsContact CB-O 3.27Å; Y790-Y794 WeakPolarHBondContact CB-O 3.39Å; Y790-P796 HydrophobicContact CD2-CG 3.69Å; Y790-P796 HydrophobicContact CE2-CB 4.22Å; Y790-P796 HydrophobicContact CE2-CG 3.68Å; Y790-I801 HydrophobicContact CD1-CD1 3.85Å; Y790-I801 HydrophobicContact CD1-CG1 4.06Å; Y790-I801 HydrophobicContact CD1-CG2 4.15Å; Y790-I801 HydrophobicContact CE1-CB 4.33Å; Y790-I801 HydrophobicContact CE1-CD1 3.85Å; Y790-I801 HydrophobicContact CE1-CG1 4.05Å; Y790-I801 HydrophobicContact CE1-CG2 3.34Å; Y790-W805 PolarHBondContact OH-NE1 2.87Å; Y790-I848 WeakPolarHBondContact CA-O 3.41Å; Y790-I848 HydrophobicContact CD1-CB 4.05Å; Y790-I848 HydrophobicContact CE1-CB 4.35Å; Y790-I848 HydrophobicContact CE1-CD1 3.98Å; Y790-I848 HydrophobicContact CE1-CG1 4.38Å
791T88.1Confident91.2Very high53 Ų5355 Ų5533%0.32530%0.303SS..EExtended strand (participates in β ladder)trans-136.6166.4-17459.60000111.7G793 T847 I848 A849 A850T791-G793 PolarHBondContact O-N 3.36Å; T791-G793 VanDerWaalsContact O-N 3.13Å; T791-T847 HydrophobicContact CG2-CG2 3.68Å; T791-T847 WeakPolarHBondContact OG1-CG2 3.42Å; T791-I848 PolarHBondContact N-O 2.97Å; T791-I848 PolarHBondContact OG1-O 3.24Å; T791-A849 WeakPolarHBondContact O-CA 3.45Å; T791-A850 PolarHBondContact O-N 3.43Å
792S79.1Confident91.2Very high97 Ų9759.2 Ų59.268%0.67832%0.322SS*.THydrogen-bonded Turntrans60.623.2171.7-54.30000115.8A850S792-A850 WeakPolarHBondContact O-CB 3.32Å
793G78.5Confident91.3Very high65 Ų6558.3 Ų58.367%0.6732%0.315SS*.THydrogen-bonded Turntrans123.5-8.6171.800000115.9T791T791-G793 PolarHBondContact O-N 3.36Å; T791-G793 VanDerWaalsContact O-N 3.13Å
794Y90.8Very high91.3Very high18 Ų1857.2 Ų57.27%0.07131%0.309CS..  trans-90.2141.3173.8-75.8-44.2000113.5Y790 D798 V800 I801 I848 A850 L870 P871 E872Y790-Y794 VanDerWaalsContact CB-O 3.27Å; Y790-Y794 WeakPolarHBondContact CB-O 3.39Å; Y794-D798 VanDerWaalsContact CA-OD2 3.32Å; Y794-D798 WeakPolarHBondContact CA-OD2 3.4Å; Y794-D798 HydrophobicContact CD1-CB 4.33Å; Y794-V800 HydrophobicContact CE1-CB 4.01Å; Y794-V800 HydrophobicContact CE1-CG1 4.22Å; Y794-V800 HydrophobicContact CE1-CG2 4.47Å; Y794-I801 HydrophobicContact CD1-CD1 4.19Å; Y794-I801 HydrophobicContact CD1-CG1 4.07Å; Y794-I801 HydrophobicContact CD2-CD1 3.74Å; Y794-I801 HydrophobicContact CD2-CG1 4.44Å; Y794-I801 HydrophobicContact CE2-CD1 4.21Å; Y794-I801 HydrophobicContact CG-CD1 3.74Å; Y794-I801 HydrophobicContact CG-CG1 3.93Å; Y794-I848 HydrophobicContact CD2-CG2 4.03Å; Y794-I848 HydrophobicContact CE2-CG2 4.3Å; Y794-A850 HydrophobicContact CD1-CB 4.14Å; Y794-A850 HydrophobicContact CD2-CB 3.54Å; Y794-A850 HydrophobicContact CE1-CB 4.06Å; Y794-A850 HydrophobicContact CE2-CB 3.48Å; Y794-A850 VanDerWaalsContact CE2-CB 3.48Å; Y794-A850 HydrophobicContact CG-CB 3.86Å; Y794-L870 HydrophobicContact CE2-CB 4.12Å; Y794-L870 VanDerWaalsContact CE2-O 3.32Å; Y794-L870 WeakPolarHBondContact CE2-O 3.19Å; Y794-L870 PolarHBondContact OH-O 3.13Å; Y794-P871 VanDerWaalsContact OH-C 3.29Å; Y794-P871 PolarHBondContact OH-O 3.15Å; Y794-E872 HydrophobicContact CE1-CG 4.04Å; Y794-E872 WeakPolarHBondContact OH-CA 3.27Å; Y794-E872 WeakPolarHBondContact OH-CG 3.39Å; Y794-E872 PolarHBondContact OH-N 2.6Å
795D89.4Confident91.4Very high88 Ų8857.6 Ų57.647%0.47131%0.31SS..  trans-117151.1167.9-171.7-85.7000110.2E797 D798D795-E797 PolarHBondContact O-N 3.44Å; D795-E797 PolarHBondContact OD1-N 3.09Å; D795-D798 PolarHBondContact N-OD2 3.31Å; D795-D798 WeakPolarHBondContact O-CB 3.47Å; D795-D798 PolarHBondContact O-N 3.21Å
796P87.7Confident91.4Very high63 Ų6360.4 Ų60.441%0.40932%0.319SS..THydrogen-bonded Turntrans-49.7-30173.9-27.931.8000115.2Y790 D798Y790-P796 HydrophobicContact CD2-CG 3.69Å; Y790-P796 HydrophobicContact CE2-CB 4.22Å; Y790-P796 HydrophobicContact CE2-CG 3.68Å; P796-D798 VanDerWaalsContact C-N 3.32Å
797E89.7Confident91.5Very high138 Ų13852.2 Ų52.265%0.64529%0.288SS*.THydrogen-bonded Turntrans-81.5-7.5-179.4-62.3-57.4145.100113.8D795 Q802D795-E797 PolarHBondContact O-N 3.44Å; D795-E797 PolarHBondContact OD1-N 3.09Å; E797-Q802 PolarHBondContact O-NE2 3.06Å
798D92.6Very high91.6Very high54 Ų5450.9 Ų50.929%0.28928%0.28SS..SBendtrans-66.4139.3-178.2-77.1-37000112.2Y794 D795 P796 V800 I801 Q802Y794-D798 VanDerWaalsContact CA-OD2 3.32Å; Y794-D798 WeakPolarHBondContact CA-OD2 3.4Å; Y794-D798 HydrophobicContact CD1-CB 4.33Å; D795-D798 PolarHBondContact N-OD2 3.31Å; D795-D798 WeakPolarHBondContact O-CB 3.47Å; D795-D798 PolarHBondContact O-N 3.21Å; P796-D798 VanDerWaalsContact C-N 3.32Å; D798-V800 PolarHBondContact O-N 3.36Å; D798-V800 VanDerWaalsContact O-N 3.15Å; D798-I801 HydrophobicContact CB-CG1 4.26Å; D798-I801 PolarHBondContact O-N 3.02Å; D798-Q802 PolarHBondContact O-N 3.48Å
799P90.9Very high91.6Very high68 Ų6855.1 Ų55.144%0.44230%0.295SS..Hα-helixtrans-54.4-39.3-179.1-27.133.8000113.4I801 Q802 W803P799-I801 PolarHBondContact O-N 3.5Å; P799-Q802 PolarHBondContact O-N 3.44Å; P799-W803 HydrophobicContact CB-CD2 4.5Å; P799-W803 HydrophobicContact CB-CH2 4.05Å; P799-W803 HydrophobicContact CB-CZ2 3.8Å; P799-W803 HydrophobicContact CB-CZ3 4.48Å; P799-W803 WeakPolarHBondContact O-CB 3.38Å; P799-W803 VanDerWaalsContact O-CD1 3.31Å; P799-W803 PolarHBondContact O-N 2.95Å
800V92.7Very high91.5Very high16 Ų1658.9 Ų58.910%0.09731%0.306CS..Hα-helixtrans-64.8-39.4-179.3-1780000111.4Y794 D798 W803 F804 L870 L879Y794-V800 HydrophobicContact CE1-CB 4.01Å; Y794-V800 HydrophobicContact CE1-CG1 4.22Å; Y794-V800 HydrophobicContact CE1-CG2 4.47Å; D798-V800 PolarHBondContact O-N 3.36Å; D798-V800 VanDerWaalsContact O-N 3.15Å; V800-W803 HydrophobicContact CG2-CE3 4.29Å; V800-W803 HydrophobicContact CG2-CZ3 4.17Å; V800-W803 PolarHBondContact O-N 2.98Å; V800-F804 WeakPolarHBondContact O-CB 3.37Å; V800-F804 PolarHBondContact O-N 3.35Å; V800-L870 HydrophobicContact CG1-CD2 3.97Å; V800-L870 HydrophobicContact CG1-CG 4.42Å; V800-L879 HydrophobicContact CG1-CD1 3.89Å
801I95.6Very high91.4Very high2 Ų256.8 Ų56.81%0.0130%0.298CS..Hα-helixtrans-70.3-42.9177.3-63.6-52.1000111.1Y790 Y794 D798 P799 W803 F804 W805 I848 L870Y790-I801 HydrophobicContact CD1-CD1 3.85Å; Y790-I801 HydrophobicContact CD1-CG1 4.06Å; Y790-I801 HydrophobicContact CD1-CG2 4.15Å; Y790-I801 HydrophobicContact CE1-CB 4.33Å; Y790-I801 HydrophobicContact CE1-CD1 3.85Å; Y790-I801 HydrophobicContact CE1-CG1 4.05Å; Y790-I801 HydrophobicContact CE1-CG2 3.34Å; Y794-I801 HydrophobicContact CD1-CD1 4.19Å; Y794-I801 HydrophobicContact CD1-CG1 4.07Å; Y794-I801 HydrophobicContact CD2-CD1 3.74Å; Y794-I801 HydrophobicContact CD2-CG1 4.44Å; Y794-I801 HydrophobicContact CE2-CD1 4.21Å; Y794-I801 HydrophobicContact CG-CD1 3.74Å; Y794-I801 HydrophobicContact CG-CG1 3.93Å; D798-I801 HydrophobicContact CB-CG1 4.26Å; D798-I801 PolarHBondContact O-N 3.02Å; P799-I801 PolarHBondContact O-N 3.5Å; I801-W803 VanDerWaalsContact C-N 3.31Å; I801-W803 PolarHBondContact O-N 3.48Å; I801-F804 WeakPolarHBondContact O-CB 3.41Å; I801-F804 PolarHBondContact O-N 3.25Å; I801-W805 PolarHBondContact O-N 3.07Å; I801-W805 VanDerWaalsContact O-N 3.08Å; I801-I848 HydrophobicContact CD1-CB 4.47Å; I801-I848 HydrophobicContact CD1-CD1 4.32Å; I801-I848 HydrophobicContact CD1-CG2 3.9Å; I801-L870 HydrophobicContact CD1-CD2 4.45Å
802Q94.4Very high91.5Very high99 Ų9957.7 Ų57.746%0.46330%0.303SS..Hα-helixtrans-62-40.6174.2-65.5-1752.400111.6E797 D798 P799 K806E797-Q802 PolarHBondContact O-NE2 3.06Å; D798-Q802 PolarHBondContact O-N 3.48Å; P799-Q802 PolarHBondContact O-N 3.44Å; Q802-K806 VanDerWaalsContact O-CB 3.23Å; Q802-K806 WeakPolarHBondContact O-CB 3.26Å; Q802-K806 PolarHBondContact O-N 3.3Å
803W95.9Very high91.8Very high70 Ų7055.5 Ų55.527%0.26528%0.282SS..Hα-helixtrans-64-44.5174.6-65.2-16.7000111.9P799 V800 I801 K806 V807 Y873 Q876 L879P799-W803 HydrophobicContact CB-CD2 4.5Å; P799-W803 HydrophobicContact CB-CH2 4.05Å; P799-W803 HydrophobicContact CB-CZ2 3.8Å; P799-W803 HydrophobicContact CB-CZ3 4.48Å; P799-W803 WeakPolarHBondContact O-CB 3.38Å; P799-W803 VanDerWaalsContact O-CD1 3.31Å; P799-W803 PolarHBondContact O-N 2.95Å; V800-W803 HydrophobicContact CG2-CE3 4.29Å; V800-W803 HydrophobicContact CG2-CZ3 4.17Å; V800-W803 PolarHBondContact O-N 2.98Å; I801-W803 VanDerWaalsContact C-N 3.31Å; I801-W803 PolarHBondContact O-N 3.48Å; W803-K806 PolarHBondContact O-N 2.84Å; W803-V807 WeakPolarHBondContact O-CG2 3.15Å; W803-V807 PolarHBondContact O-N 3.39Å; W803-Y873 WeakPolarHBondContact CZ3-O 3.45Å; W803-Q876 HydrophobicContact CB-CB 4.21Å; W803-Q876 HydrophobicContact CB-CG 4.08Å; W803-Q876 HydrophobicContact CD2-CB 4.14Å; W803-Q876 HydrophobicContact CG-CB 3.85Å; W803-Q876 HydrophobicContact CG-CG 4.17Å; W803-L879 HydrophobicContact CB-CD1 4.15Å
804F95.9Very high92.1Very high0 Ų055.6 Ų55.60%027%0.265CS..Hα-helixtrans-54.3-56.8176.7174.1-99.4000110.9V800 I801 K806 V807 V808 L819 F846 I848 L868 L870 L879 L883V800-F804 WeakPolarHBondContact O-CB 3.37Å; V800-F804 PolarHBondContact O-N 3.35Å; I801-F804 WeakPolarHBondContact O-CB 3.41Å; I801-F804 PolarHBondContact O-N 3.25Å; F804-K806 VanDerWaalsContact C-N 3.3Å; F804-K806 PolarHBondContact O-N 3.4Å; F804-V807 CarbonylContact O-C 3.47Å; F804-V807 WeakPolarHBondContact O-CA 3.49Å; F804-V807 WeakPolarHBondContact O-CB 3.32Å; F804-V807 PolarHBondContact O-N 3.3Å; F804-V808 HydrophobicContact CD1-CG2 4.23Å; F804-V808 HydrophobicContact CD2-CG2 4.37Å; F804-V808 HydrophobicContact CE1-CG2 3.85Å; F804-V808 HydrophobicContact CE2-CG2 4.01Å; F804-V808 HydrophobicContact CG-CG2 4.48Å; F804-V808 HydrophobicContact CZ-CG2 3.74Å; F804-V808 WeakPolarHBondContact O-CG2 3.27Å; F804-V808 PolarHBondContact O-N 3.48Å; F804-L819 HydrophobicContact CE2-CD2 4.37Å; F804-L819 HydrophobicContact CZ-CD2 4.03Å; F804-F846 HydrophobicContact CZ-CZ 4.37Å; F804-I848 HydrophobicContact CD1-CD1 3.74Å; F804-I848 HydrophobicContact CE1-CD1 3.63Å; F804-I848 HydrophobicContact CG-CD1 4.47Å; F804-I848 HydrophobicContact CZ-CD1 4.28Å; F804-L868 HydrophobicContact CD2-CD2 4.38Å; F804-L868 HydrophobicContact CE2-CD2 3.53Å; F804-L868 HydrophobicContact CZ-CD2 3.68Å; F804-L870 HydrophobicContact CB-CD2 4.13Å; F804-L870 HydrophobicContact CD2-CD2 4.12Å; F804-L870 HydrophobicContact CG-CD2 4.25Å; F804-L879 HydrophobicContact CB-CD1 4.33Å; F804-L883 HydrophobicContact CD2-CD2 4.28Å; F804-L883 HydrophobicContact CE2-CD1 4.48Å; F804-L883 HydrophobicContact CE2-CD2 4.1Å
805W96.1Very high91.9Very high8 Ų856.4 Ų56.43%0.0327%0.27CS..Hα-helixtrans-66.8-30.4-179.2-71.5114.2000113.4V781 W784 C785 T788 Y790 I801 V807 V808 R809 F846V781-W805 HydrophobicContact CG1-CE3 4.01Å; V781-W805 HydrophobicContact CG1-CZ3 4.14Å; W784-W805 HydrophobicContact CB-CH2 4.21Å; W784-W805 HydrophobicContact CB-CZ3 4.31Å; W784-W805 AromaticContact CD1-CH2 3.91Å; W784-W805 HydrophobicContact CD2-CH2 4.19Å; W784-W805 HydrophobicContact CD2-CZ3 4.38Å; W784-W805 AromaticContact CG-CH2 3.84Å; W784-W805 HydrophobicContact CG-CH2 3.84Å; W784-W805 HydrophobicContact CG-CZ3 4.22Å; C785-W805 HydrophobicContact CB-CD2 3.96Å; C785-W805 HydrophobicContact CB-CE3 3.98Å; C785-W805 HydrophobicContact CB-CH2 4.24Å; C785-W805 HydrophobicContact CB-CZ2 4.21Å; C785-W805 HydrophobicContact CB-CZ3 4.12Å; T788-W805 HydrophobicContact CG2-CZ2 4.09Å; T788-W805 WeakPolarHBondContact OG1-CZ2 3.38Å; Y790-W805 PolarHBondContact OH-NE1 2.87Å; I801-W805 PolarHBondContact O-N 3.07Å; I801-W805 VanDerWaalsContact O-N 3.08Å; W805-V807 VanDerWaalsContact C-N 3.33Å; W805-V808 HydrophobicContact CE3-CB 4.13Å; W805-V808 HydrophobicContact CE3-CG1 4.16Å; W805-V808 HydrophobicContact CE3-CG2 4.4Å; W805-V808 HydrophobicContact CZ3-CG1 4.13Å; W805-V808 PolarHBondContact O-N 3.24Å; W805-R809 VanDerWaalsContact O-CG 3.29Å; W805-R809 WeakPolarHBondContact O-CG 3.45Å; W805-R809 PolarHBondContact O-N 3.03Å; W805-F846 HydrophobicContact CH2-CE1 4.23Å; W805-F846 HydrophobicContact CZ2-CE1 4.1Å
806K94.2Very high92Very high90 Ų9054.5 Ų54.539%0.39126%0.256SS..Hα-helixtrans-67.4-34.6172.1-173.6179.5175-161.90112.1Q802 W803 F804 R810Q802-K806 VanDerWaalsContact O-CB 3.23Å; Q802-K806 WeakPolarHBondContact O-CB 3.26Å; Q802-K806 PolarHBondContact O-N 3.3Å; W803-K806 PolarHBondContact O-N 2.84Å; F804-K806 VanDerWaalsContact C-N 3.3Å; F804-K806 PolarHBondContact O-N 3.4Å; K806-R810 WeakPolarHBondContact O-CG 3.23Å
807V94.9Very high92.1Very high0 Ų051.5 Ų51.50%024%0.237CC..Hα-helixtrans-68.4-51171.7170.10000109.7W803 F804 W805 R809 R810 L811 Q876 L879 R880 L883W803-V807 WeakPolarHBondContact O-CG2 3.15Å; W803-V807 PolarHBondContact O-N 3.39Å; F804-V807 CarbonylContact O-C 3.47Å; F804-V807 WeakPolarHBondContact O-CA 3.49Å; F804-V807 WeakPolarHBondContact O-CB 3.32Å; F804-V807 PolarHBondContact O-N 3.3Å; W805-V807 VanDerWaalsContact C-N 3.33Å; V807-R809 VanDerWaalsContact C-N 3.31Å; V807-R809 PolarHBondContact O-N 3.08Å; V807-R810 CarbonylContact O-C 3.57Å; V807-R810 WeakPolarHBondContact O-CA 3.25Å; V807-R810 WeakPolarHBondContact O-CB 3.37Å; V807-R810 PolarHBondContact O-N 2.77Å; V807-L811 HydrophobicContact CG1-CD2 4.21Å; V807-L811 HydrophobicContact CG1-CG 4.45Å; V807-L811 WeakPolarHBondContact O-CG 3.49Å; V807-L811 PolarHBondContact O-N 3.11Å; V807-Q876 HydrophobicContact CG2-CG 4.01Å; V807-L879 HydrophobicContact CB-CD2 4.3Å; V807-L879 HydrophobicContact CG2-CD2 4.07Å; V807-R880 HydrophobicContact CG1-CB 4.18Å; V807-R880 HydrophobicContact CG1-CG 4.07Å; V807-R880 HydrophobicContact CG2-CB 3.97Å; V807-L883 HydrophobicContact CG1-CD2 4.18Å
808V94.9Very high92Very high0 Ų046.4 Ų46.40%021%0.214CC..Hα-helixtrans-55.9-40.9-180176.60000112.6V781 F804 W805 R810 L811 R816 L819V781-V808 HydrophobicContact CG1-CG1 3.84Å; V781-V808 HydrophobicContact CG2-CG1 4.32Å; F804-V808 HydrophobicContact CD1-CG2 4.23Å; F804-V808 HydrophobicContact CD2-CG2 4.37Å; F804-V808 HydrophobicContact CE1-CG2 3.85Å; F804-V808 HydrophobicContact CE2-CG2 4.01Å; F804-V808 HydrophobicContact CG-CG2 4.48Å; F804-V808 HydrophobicContact CZ-CG2 3.74Å; F804-V808 WeakPolarHBondContact O-CG2 3.27Å; F804-V808 PolarHBondContact O-N 3.48Å; W805-V808 HydrophobicContact CE3-CB 4.13Å; W805-V808 HydrophobicContact CE3-CG1 4.16Å; W805-V808 HydrophobicContact CE3-CG2 4.4Å; W805-V808 HydrophobicContact CZ3-CG1 4.13Å; W805-V808 PolarHBondContact O-N 3.24Å; V808-R810 PolarHBondContact O-N 3.4Å; V808-L811 HydrophobicContact CG2-CD1 4.48Å; V808-L811 WeakPolarHBondContact O-CB 3.44Å; V808-L811 PolarHBondContact O-N 2.92Å; V808-R816 PolarHBondContact O-NE 3.33Å; V808-L819 HydrophobicContact CG1-CD2 4.33Å; V808-L819 HydrophobicContact CG2-CD2 3.61Å
809R94.7Very high91.9Very high103 Ų10343.9 Ų43.939%0.38920%0.2SC..Hα-helixtrans-62.1-30.7174.3-73.8177.8-174.9103.2-0.5113.4V781 E782 W805 V807 R816V781-R809 HydrophobicContact CG1-CG 3.85Å; E782-R809 IonicContact OE1-CZ 3.46Å; E782-R809 IonicContact OE1-NE 2.68Å; E782-R809 PolarHBondContact OE1-NE 3.45Å; E782-R809 IonicContact OE1-NH2 3.38Å; E782-R809 PolarHBondContact OE1-NH2 2.86Å; E782-R809 IonicContact OE2-CZ 3.51Å; E782-R809 IonicContact OE2-NE 2.62Å; E782-R809 IonicContact OE2-NH2 3.48Å; E782-R809 PolarHBondContact OE2-NH2 3.28Å; W805-R809 VanDerWaalsContact O-CG 3.29Å; W805-R809 WeakPolarHBondContact O-CG 3.45Å; W805-R809 PolarHBondContact O-N 3.03Å; V807-R809 VanDerWaalsContact C-N 3.31Å; V807-R809 PolarHBondContact O-N 3.08Å; R809-R816 PolarHBondContact O-NH2 3.17Å
810R92.9Very high91.8Very high157 Ų15740.6 Ų40.659%0.59218%0.179SC*.Hα-helixtrans-88.7-11.2179.2-69.3179.1177.6-157.6-2.6113.7K806 V807 V808K806-R810 WeakPolarHBondContact O-CG 3.23Å; V807-R810 CarbonylContact O-C 3.57Å; V807-R810 WeakPolarHBondContact O-CA 3.25Å; V807-R810 WeakPolarHBondContact O-CB 3.37Å; V807-R810 PolarHBondContact O-N 2.77Å; V808-R810 PolarHBondContact O-N 3.4Å
811L90.9Very high91.5Very high3 Ų340 Ų402%0.01618%0.175CC..SBendtrans-65.1149.1174.1-66.2-177.2000110.5V807 V808 E815 R816 L819 L884V807-L811 HydrophobicContact CG1-CD2 4.21Å; V807-L811 HydrophobicContact CG1-CG 4.45Å; V807-L811 WeakPolarHBondContact O-CG 3.49Å; V807-L811 PolarHBondContact O-N 3.11Å; V808-L811 HydrophobicContact CG2-CD1 4.48Å; V808-L811 WeakPolarHBondContact O-CB 3.44Å; V808-L811 PolarHBondContact O-N 2.92Å; L811-E815 WeakPolarHBondContact CA-OE2 3.27Å; L811-E815 HydrophobicContact CB-CB 3.8Å; L811-E815 HydrophobicContact CD1-CB 4.25Å; L811-E815 HydrophobicContact CD2-CB 4.12Å; L811-E815 WeakPolarHBondContact CD2-OE2 3.43Å; L811-E815 HydrophobicContact CG-CB 4.25Å; L811-R816 HydrophobicContact CB-CG 3.91Å; L811-R816 VanDerWaalsContact O-CZ 3.3Å; L811-R816 PolarHBondContact O-NE 3.34Å; L811-R816 PolarHBondContact O-NH2 3.03Å; L811-R816 VanDerWaalsContact O-NH2 3.11Å; L811-L819 HydrophobicContact CD1-CD2 4.44Å; L811-L884 HydrophobicContact CD2-CD2 3.84Å
812T88.7Confident91Very high72 Ų7241.2 Ų41.244%0.44218%0.18SC..  trans-65.5166.2169.170.40000110.4E814 E815 R816T812-E814 VanDerWaalsContact C-N 3.27Å; T812-E814 PolarHBondContact O-N 2.73Å; T812-E815 PolarHBondContact N-OE2 3.44Å; T812-E815 PolarHBondContact O-N 3.5Å; T812-E815 WeakPolarHBondContact OG1-CG 3.43Å; T812-E815 PolarHBondContact OG1-N 3.48Å; T812-E815 PolarHBondContact OG1-OE2 3.38Å; T812-R816 WeakPolarHBondContact O-CG 3.31Å; T812-R816 PolarHBondContact O-N 2.77Å
813Q86.3Confident90.6Very high51 Ų5136.5 Ų36.524%0.23816%0.158CC..Hα-helixtrans-61.2-39.8177.4-169.856.926.600111.6M776 P777 R816 V817M776-Q813 HydrophobicContact CG-CG 4.33Å; M776-Q813 HydrophobicContact SD-CB 4.32Å; M776-Q813 HydrophobicContact SD-CG 3.96Å; P777-Q813 PolarHBondContact O-NE2 2.62Å; Q813-R816 PolarHBondContact O-N 3.18Å; Q813-V817 VanDerWaalsContact O-CG2 3.31Å; Q813-V817 WeakPolarHBondContact O-CG2 3.41Å; Q813-V817 PolarHBondContact O-N 3.3Å
814E83.9Confident90Very high67 Ų6733.6 Ų33.631%0.31315%0.148SC..Hα-helixtrans-59.5-49.2175.3-69.4171.9-176.500111.7M776 T812 R816 V817 L818M776-E814 HydrophobicContact CE-CG 3.45Å; M776-E814 VanDerWaalsContact CE-CG 3.45Å; M776-E814 HydrophobicContact SD-CG 4.16Å; T812-E814 VanDerWaalsContact C-N 3.27Å; T812-E814 PolarHBondContact O-N 2.73Å; E814-R816 VanDerWaalsContact C-N 3.3Å; E814-R816 PolarHBondContact O-N 3.49Å; E814-V817 PolarHBondContact O-N 3.43Å; E814-V817 VanDerWaalsContact O-N 3.16Å; E814-L818 WeakPolarHBondContact O-CG 3.41Å; E814-L818 PolarHBondContact O-N 3Å
815E87.5Confident89.1Confident35 Ų3534.1 Ų34.116%0.16415%0.153CC..Hα-helixtrans-62.8-34.9178.7-72.6170.915500112.5L811 T812 L819 L884L811-E815 WeakPolarHBondContact CA-OE2 3.27Å; L811-E815 HydrophobicContact CB-CB 3.8Å; L811-E815 HydrophobicContact CD1-CB 4.25Å; L811-E815 HydrophobicContact CD2-CB 4.12Å; L811-E815 WeakPolarHBondContact CD2-OE2 3.43Å; L811-E815 HydrophobicContact CG-CB 4.25Å; T812-E815 PolarHBondContact N-OE2 3.44Å; T812-E815 PolarHBondContact O-N 3.5Å; T812-E815 WeakPolarHBondContact OG1-CG 3.43Å; T812-E815 PolarHBondContact OG1-N 3.48Å; T812-E815 PolarHBondContact OG1-OE2 3.38Å; E815-L819 PolarHBondContact O-N 2.73Å; E815-L884 HydrophobicContact CG-CD2 4.31Å
816R92.3Very high88.4Confident49 Ų4933.8 Ų33.819%0.18515%0.152CC..Hα-helixtrans-68.1-38.9174.9-68.5171.5-167.7155.41.7112.1I779 V808 R809 L811 T812 Q813 E814 L819 L820I779-R816 HydrophobicContact CD1-CB 3.93Å; V808-R816 PolarHBondContact O-NE 3.33Å; R809-R816 PolarHBondContact O-NH2 3.17Å; L811-R816 HydrophobicContact CB-CG 3.91Å; L811-R816 VanDerWaalsContact O-CZ 3.3Å; L811-R816 PolarHBondContact O-NE 3.34Å; L811-R816 PolarHBondContact O-NH2 3.03Å; L811-R816 VanDerWaalsContact O-NH2 3.11Å; T812-R816 WeakPolarHBondContact O-CG 3.31Å; T812-R816 PolarHBondContact O-N 2.77Å; Q813-R816 PolarHBondContact O-N 3.18Å; E814-R816 VanDerWaalsContact C-N 3.3Å; E814-R816 PolarHBondContact O-N 3.49Å; R816-L819 PolarHBondContact O-N 2.88Å; R816-L820 PolarHBondContact O-N 3.34Å
817V89.2Confident88Confident0 Ų029.5 Ų29.50%013%0.134CC..Hα-helixtrans-67.9-41.2176.8173.90000110.5L771 M776 P777 I779 Q813 E814 L819 L820 Q821L771-V817 HydrophobicContact CD1-CG1 4.04Å; L771-V817 HydrophobicContact CD2-CG1 3.52Å; L771-V817 HydrophobicContact CG-CG1 4.38Å; M776-V817 HydrophobicContact CG-CG2 4.33Å; P777-V817 HydrophobicContact CG-CG1 4.48Å; P777-V817 HydrophobicContact CG-CG2 3.92Å; I779-V817 HydrophobicContact CD1-CB 4.32Å; I779-V817 HydrophobicContact CD1-CG2 3.65Å; I779-V817 HydrophobicContact CG1-CG2 4.4Å; Q813-V817 VanDerWaalsContact O-CG2 3.31Å; Q813-V817 WeakPolarHBondContact O-CG2 3.41Å; Q813-V817 PolarHBondContact O-N 3.3Å; E814-V817 PolarHBondContact O-N 3.43Å; E814-V817 VanDerWaalsContact O-N 3.16Å; V817-L819 VanDerWaalsContact C-N 3.32Å; V817-L819 PolarHBondContact O-N 2.98Å; V817-L820 WeakPolarHBondContact O-CB 3.28Å; V817-L820 PolarHBondContact O-N 2.85Å; V817-L820 VanDerWaalsContact O-N 3.12Å; V817-Q821 HydrophobicContact CG1-CG 4.47Å; V817-Q821 WeakPolarHBondContact O-CG 3.36Å; V817-Q821 PolarHBondContact O-N 2.93Å
818L86.9Confident87.5Confident31 Ų3133.4 Ų33.416%0.16215%0.149CC..Hα-helixtrans-59.6-42.7172.3-73.1173.4000111.7Y767 E814 L820 Q821 F822Y767-L818 HydrophobicContact CD1-CD2 4.33Å; Y767-L818 HydrophobicContact CG-CD2 4.28Å; E814-L818 WeakPolarHBondContact O-CG 3.41Å; E814-L818 PolarHBondContact O-N 3Å; L818-L820 VanDerWaalsContact C-N 3.31Å; L818-L820 PolarHBondContact O-N 2.97Å; L818-Q821 PolarHBondContact O-N 3.15Å; L818-F822 WeakPolarHBondContact O-CB 3.36Å; L818-F822 PolarHBondContact O-N 3.42Å
819L90.4Very high87Confident0 Ų035.4 Ų35.40%016%0.161CC..Hα-helixtrans-61.6-40174.2178.661.3000112.3W784 F804 V808 L811 E815 R816 V817 F822 V823 L883 L887W784-L819 HydrophobicContact CH2-CB 4.46Å; W784-L819 HydrophobicContact CH2-CD2 4.24Å; W784-L819 HydrophobicContact CH2-CG 4Å; F804-L819 HydrophobicContact CE2-CD2 4.37Å; F804-L819 HydrophobicContact CZ-CD2 4.03Å; V808-L819 HydrophobicContact CG1-CD2 4.33Å; V808-L819 HydrophobicContact CG2-CD2 3.61Å; L811-L819 HydrophobicContact CD1-CD2 4.44Å; E815-L819 PolarHBondContact O-N 2.73Å; R816-L819 PolarHBondContact O-N 2.88Å; V817-L819 VanDerWaalsContact C-N 3.32Å; V817-L819 PolarHBondContact O-N 2.98Å; L819-F822 PolarHBondContact O-N 2.86Å; L819-V823 HydrophobicContact CD1-CG2 4.22Å; L819-V823 WeakPolarHBondContact O-CG2 3.41Å; L819-V823 PolarHBondContact O-N 2.9Å; L819-L883 HydrophobicContact CD1-CD1 4.14Å; L819-L887 HydrophobicContact CB-CD1 4.05Å; L819-L887 HydrophobicContact CB-CD2 4.14Å; L819-L887 HydrophobicContact CD1-CD2 3.96Å
820L90.1Very high86.5Confident0 Ų031.7 Ų31.70%015%0.15CC..Hα-helixtrans-63.5-52.8176.5-177.358.3000110.4I779 W784 R816 V817 L818 F822 V823 T824 S827 V829 F834I779-L820 HydrophobicContact CD1-CB 4.24Å; I779-L820 HydrophobicContact CD1-CD2 4.04Å; W784-L820 HydrophobicContact CH2-CB 3.82Å; W784-L820 HydrophobicContact CH2-CD1 3.93Å; W784-L820 HydrophobicContact CH2-CG 4.48Å; W784-L820 HydrophobicContact CZ2-CD1 3.88Å; W784-L820 HydrophobicContact CZ3-CB 4.29Å; R816-L820 PolarHBondContact O-N 3.34Å; V817-L820 WeakPolarHBondContact O-CB 3.28Å; V817-L820 PolarHBondContact O-N 2.85Å; V817-L820 VanDerWaalsContact O-N 3.12Å; L818-L820 VanDerWaalsContact C-N 3.31Å; L818-L820 PolarHBondContact O-N 2.97Å; L820-F822 VanDerWaalsContact C-N 3.25Å; L820-F822 PolarHBondContact O-N 3.02Å; L820-V823 PolarHBondContact O-N 2.8Å; L820-T824 HydrophobicContact CD1-CG2 3.64Å; L820-T824 PolarHBondContact O-N 3.15Å; L820-T824 PolarHBondContact O-OG1 2.88Å; L820-S827 WeakPolarHBondContact CD2-O 3.5Å; L820-V829 HydrophobicContact CD2-CG2 3.99Å; L820-F834 HydrophobicContact CD1-CE1 3.75Å; L820-F834 HydrophobicContact CD1-CZ 4.37Å; L820-F834 HydrophobicContact CD2-CE1 4.46Å; L820-F834 HydrophobicContact CD2-CZ 4.42Å
821Q85.8Confident85.6Confident3 Ų332.1 Ų32.11%0.01416%0.158CC..Hα-helixtrans-55.7-40.6176.1-73.7173.9-49.300112.2Y767 E770 V817 L818 V823 G825Y767-Q821 HydrophobicContact CD1-CB 3.88Å; Y767-Q821 HydrophobicContact CD1-CG 4.39Å; Y767-Q821 HydrophobicContact CE1-CB 4.11Å; Y767-Q821 PolarHBondContact O-NE2 3.01Å; E770-Q821 PolarHBondContact OE2-NE2 2.93Å; V817-Q821 HydrophobicContact CG1-CG 4.47Å; V817-Q821 WeakPolarHBondContact O-CG 3.36Å; V817-Q821 PolarHBondContact O-N 2.93Å; L818-Q821 PolarHBondContact O-N 3.15Å; Q821-V823 VanDerWaalsContact C-N 3.3Å; Q821-V823 PolarHBondContact O-N 3.11Å; Q821-G825 WeakPolarHBondContact O-CA 3.36Å; Q821-G825 PolarHBondContact O-N 3.37Å
822F85.3Confident85Confident28 Ų2834.9 Ų34.912%0.12319%0.187CC..Hα-helixtrans-61.8-37.2178.3-179.9-107.8000112.1L818 L819 L820 S861 L868 A886 L887L818-F822 WeakPolarHBondContact O-CB 3.36Å; L818-F822 PolarHBondContact O-N 3.42Å; L819-F822 PolarHBondContact O-N 2.86Å; L820-F822 VanDerWaalsContact C-N 3.25Å; L820-F822 PolarHBondContact O-N 3.02Å; F822-S861 WeakPolarHBondContact O-CB 3.42Å; F822-S861 PolarHBondContact O-OG 3.33Å; F822-L868 HydrophobicContact CD1-CD1 4.32Å; F822-L868 HydrophobicContact CE1-CD1 3.92Å; F822-A886 HydrophobicContact CZ-CB 4.47Å; F822-L887 HydrophobicContact CB-CD2 3.62Å; F822-L887 HydrophobicContact CD1-CD2 3.98Å; F822-L887 HydrophobicContact CD2-CD2 4.44Å; F822-L887 HydrophobicContact CG-CD2 3.77Å
823V86.3Confident84.9Confident0 Ų032.2 Ų32.20%017%0.174CC..Hα-helixtrans-97.7-27.4-174.4-172.90000114.1L819 L820 Q821 F846 T863 L868L819-V823 HydrophobicContact CD1-CG2 4.22Å; L819-V823 WeakPolarHBondContact O-CG2 3.41Å; L819-V823 PolarHBondContact O-N 2.9Å; L820-V823 PolarHBondContact O-N 2.8Å; Q821-V823 VanDerWaalsContact C-N 3.3Å; Q821-V823 PolarHBondContact O-N 3.11Å; V823-F846 HydrophobicContact CB-CD2 4.29Å; V823-F846 HydrophobicContact CB-CE2 3.78Å; V823-F846 HydrophobicContact CG1-CD2 3.66Å; V823-F846 HydrophobicContact CG1-CE2 3.36Å; V823-F846 HydrophobicContact CG2-CE2 3.94Å; V823-T863 VanDerWaalsContact O-CA 3.31Å; V823-T863 WeakPolarHBondContact O-CA 3.43Å; V823-L868 HydrophobicContact CG1-CB 4.17Å; V823-L868 HydrophobicContact CG2-CB 4.07Å; V823-L868 HydrophobicContact CG2-CD1 3.93Å; V823-L868 HydrophobicContact CG2-CG 4.45Å
824T83.1Confident85.2Confident8 Ų829.9 Ų29.95%0.04916%0.163CC..Hα-helixtrans-110.2-13.9-177.666.60000113.1L820 S826 L837 N866L820-T824 HydrophobicContact CD1-CG2 3.64Å; L820-T824 PolarHBondContact O-N 3.15Å; L820-T824 PolarHBondContact O-OG1 2.88Å; T824-S826 VanDerWaalsContact C-N 3.29Å; T824-S826 PolarHBondContact OG1-N 3.2Å; T824-S826 PolarHBondContact OG1-O 2.7Å; T824-L837 HydrophobicContact CG2-CD1 4.35Å; T824-L837 HydrophobicContact CG2-CD2 3.99Å; T824-N866 HydrophobicContact CG2-CB 4.5Å
825G77.1Confident85.4Confident11 Ų1128.2 Ų28.211%0.11316%0.16CC..SBendtrans87.9-13.4-174.600000114R652 Q821R652-G825 PolarHBondContact NH2-O 2.87Å; Q821-G825 WeakPolarHBondContact O-CA 3.36Å; Q821-G825 PolarHBondContact O-N 3.37Å
826S81Confident85.4Confident1 Ų132 Ų321%0.00718%0.176CC..SBendtrans-141.4154.1-177.4176.80000112Y649 E770 T824 R828Y649-S826 VanDerWaalsContact CD1-OG 3.31Å; Y649-S826 WeakPolarHBondContact CD1-OG 3.39Å; E770-S826 PolarHBondContact OE1-OG 3.09Å; T824-S826 VanDerWaalsContact C-N 3.29Å; T824-S826 PolarHBondContact OG1-N 3.2Å; T824-S826 PolarHBondContact OG1-O 2.7Å; S826-R828 VanDerWaalsContact C-N 3.25Å; S826-R828 PolarHBondContact O-N 3.31Å; S826-R828 WeakPolarHBondContact OG-CB 3.5Å; S826-R828 PolarHBondContact OG-N 3.41Å; S826-R828 VanDerWaalsContact OG-N 3.13Å
827S86.2Confident85.1Confident0 Ų030 Ų300%017%0.169CC..  trans-77-8171.660.90000113.3E770 P777 L820 V829E770-S827 WeakPolarHBondContact OE1-CB 3.33Å; E770-S827 PolarHBondContact OE1-N 2.89Å; E770-S827 PolarHBondContact OE1-OG 2.94Å; P777-S827 WeakPolarHBondContact CG-O 3.45Å; L820-S827 WeakPolarHBondContact CD2-O 3.5Å; S827-V829 PolarHBondContact O-N 3.19Å
828R84.2Confident84.6Confident83 Ų8333.8 Ų33.831%0.31319%0.188SC..PPolyproline II helixtrans-62.1125.5-173.9-171.1-179.7-175176.41.8112.9Y649 S826Y649-R828 HydrophobicContact CD1-CB 4.22Å; Y649-R828 HydrophobicContact CD2-CB 4.21Å; Y649-R828 HydrophobicContact CD2-CG 4.26Å; Y649-R828 HydrophobicContact CE1-CB 3.85Å; Y649-R828 HydrophobicContact CE1-CG 4.48Å; Y649-R828 HydrophobicContact CE2-CB 3.86Å; Y649-R828 HydrophobicContact CE2-CG 3.66Å; Y649-R828 HydrophobicContact CG-CB 4.38Å; S826-R828 VanDerWaalsContact C-N 3.25Å; S826-R828 PolarHBondContact O-N 3.31Å; S826-R828 WeakPolarHBondContact OG-CB 3.5Å; S826-R828 PolarHBondContact OG-N 3.41Å; S826-R828 VanDerWaalsContact OG-N 3.13Å
829V85.3Confident84.1Confident42 Ų4232.3 Ų32.326%0.25518%0.181SC..PPolyproline II helixtrans-96.5123.2166.3-177.30000109P777 I779 L820 S827 F834P777-V829 HydrophobicContact CB-CG2 4.19Å; I779-V829 HydrophobicContact CG1-CG2 4.34Å; L820-V829 HydrophobicContact CD2-CG2 3.99Å; S827-V829 PolarHBondContact O-N 3.19Å; V829-F834 HydrophobicContact CG2-CZ 4.43Å
830P82.9Confident83Confident25 Ų2534.4 Ų34.416%0.16220%0.202CC..PPolyproline II helixtrans-61.5149.7179.9-22.331.5000113.6G832 G833 F836 L837P830-G832 PolarHBondContact O-N 3.03Å; P830-G832 VanDerWaalsContact O-N 3.09Å; P830-G833 PolarHBondContact O-N 2.98Å; P830-F836 HydrophobicContact CB-CB 3.93Å; P830-F836 WeakPolarHBondContact CB-O 3.32Å; P830-F836 WeakPolarHBondContact CG-O 3.36Å; P830-L837 HydrophobicContact CG-CD1 4.03Å
831H75.1Confident82.1Confident166 Ų16639.5 Ų39.577%0.76924%0.238SC*.THydrogen-bonded Turntrans-65.2111.1170.3-71.775.6000108.8
832G78.2Confident81.7Confident60 Ų6040.4 Ų40.462%0.61925%0.248SC*.THydrogen-bonded Turntrans109.91.3-17300000115P830 F836P830-G832 PolarHBondContact O-N 3.03Å; P830-G832 VanDerWaalsContact O-N 3.09Å; G832-F836 WeakPolarHBondContact O-CD2 3.46Å
833G86.8Confident81.7Confident16 Ų1644.5 Ų44.517%0.16527%0.271CS..  trans89.6-170.5174.100000114.2D783 P830 A835 F836D783-G833 WeakPolarHBondContact OD2-CA 3.36Å; P830-G833 PolarHBondContact O-N 2.98Å; G833-A835 PolarHBondContact O-N 2.89Å; G833-A835 VanDerWaalsContact O-N 3.13Å; G833-F836 PolarHBondContact O-N 3.44Å; G833-F836 VanDerWaalsContact O-N 3.09Å
834F91.1Very high81.6Confident3 Ų346.9 Ų46.91%0.01328%0.282CS..G310 helixtrans-68.2-11.6-173.5-75.6-83.4000114.1I779 D783 W784 N787 L820 V829 F836 L837I779-F834 HydrophobicContact CG2-CE2 4.08Å; I779-F834 HydrophobicContact CG2-CZ 3.99Å; D783-F834 HydrophobicContact CB-CD2 4.43Å; D783-F834 PolarHBondContact OD2-N 2.79Å; W784-F834 HydrophobicContact CB-CD1 4.22Å; W784-F834 HydrophobicContact CB-CD2 3.56Å; W784-F834 HydrophobicContact CB-CE1 4.28Å; W784-F834 HydrophobicContact CB-CE2 3.63Å; W784-F834 HydrophobicContact CB-CG 3.87Å; W784-F834 HydrophobicContact CB-CZ 4Å; W784-F834 AromaticContact CD1-CD1 3.6Å; W784-F834 AromaticContact CD1-CE1 3.86Å; W784-F834 AromaticContact CD1-CG 3.93Å; W784-F834 HydrophobicContact CD2-CD1 4.15Å; W784-F834 AromaticContact CD2-CE1 3.6Å; W784-F834 HydrophobicContact CD2-CE1 3.6Å; W784-F834 HydrophobicContact CD2-CE2 4.2Å; W784-F834 AromaticContact CD2-CZ 3.63Å; W784-F834 HydrophobicContact CD2-CZ 3.63Å; W784-F834 AromaticContact CE2-CE1 3.79Å; W784-F834 HydrophobicContact CE3-CE1 4.11Å; W784-F834 HydrophobicContact CE3-CE2 4.36Å; W784-F834 AromaticContact CE3-CZ 3.74Å; W784-F834 HydrophobicContact CE3-CZ 3.74Å; W784-F834 AromaticContact CG-CD1 3.74Å; W784-F834 HydrophobicContact CG-CD1 3.74Å; W784-F834 AromaticContact CG-CD2 3.99Å; W784-F834 HydrophobicContact CG-CD2 3.99Å; W784-F834 AromaticContact CG-CE1 3.68Å; W784-F834 HydrophobicContact CG-CE1 3.68Å; W784-F834 AromaticContact CG-CE2 3.93Å; W784-F834 HydrophobicContact CG-CE2 3.93Å; W784-F834 AromaticContact CG-CG 3.89Å; W784-F834 HydrophobicContact CG-CG 3.89Å; W784-F834 AromaticContact CG-CZ 3.77Å; W784-F834 HydrophobicContact CG-CZ 3.77Å; W784-F834 HydrophobicContact CZ2-CE1 4.44Å; W784-F834 HydrophobicContact CZ3-CZ 4.43Å; W784-F834 AromaticContact NE1-CD1 3.94Å; W784-F834 AromaticContact NE1-CE1 3.93Å; N787-F834 HydrophobicContact CB-CB 4Å; L820-F834 HydrophobicContact CD1-CE1 3.75Å; L820-F834 HydrophobicContact CD1-CZ 4.37Å; L820-F834 HydrophobicContact CD2-CE1 4.46Å; L820-F834 HydrophobicContact CD2-CZ 4.42Å; V829-F834 HydrophobicContact CG2-CZ 4.43Å; F834-F836 PolarHBondContact O-N 2.9Å; F834-L837 HydrophobicContact CD1-CD1 4.35Å; F834-L837 PolarHBondContact O-N 3.32Å
835A88.4Confident81.9Confident31 Ų3150.1 Ų50.126%0.25630%0.295SS..G310 helixtrans-63.2-26.1170.400000112.9N787 G833N787-A835 WeakPolarHBondContact OD1-CB 3.43Å; G833-A835 PolarHBondContact O-N 2.89Å; G833-A835 VanDerWaalsContact O-N 3.13Å
836F87.5Confident82.7Confident114 Ų11449.7 Ų49.750%0.529%0.29SS..G310 helixtrans-10525.1-176.4-62.9-84.7000113.3P830 G832 G833 F834 M838 L843P830-F836 HydrophobicContact CB-CB 3.93Å; P830-F836 WeakPolarHBondContact CB-O 3.32Å; P830-F836 WeakPolarHBondContact CG-O 3.36Å; G832-F836 WeakPolarHBondContact O-CD2 3.46Å; G833-F836 PolarHBondContact O-N 3.44Å; G833-F836 VanDerWaalsContact O-N 3.09Å; F834-F836 PolarHBondContact O-N 2.9Å; F836-M838 PolarHBondContact O-N 2.89Å; F836-L843 HydrophobicContact CB-CD1 4.49Å; F836-L843 HydrophobicContact CD1-CD1 4.32Å
837L85.7Confident83.3Confident7 Ų750.1 Ų50.14%0.03729%0.293CS..  trans-65132.6178.6-15772.1000110.3T824 P830 F834 Q844 F846 N866T824-L837 HydrophobicContact CG2-CD1 4.35Å; T824-L837 HydrophobicContact CG2-CD2 3.99Å; P830-L837 HydrophobicContact CG-CD1 4.03Å; F834-L837 HydrophobicContact CD1-CD1 4.35Å; F834-L837 PolarHBondContact O-N 3.32Å; L837-Q844 WeakPolarHBondContact CB-O 3.29Å; L837-Q844 CarbonylContact O-C 3.53Å; L837-Q844 PolarHBondContact O-N 3.48Å; L837-F846 HydrophobicContact CD2-CB 4.1Å; L837-N866 HydrophobicContact CD2-CB 3.83Å; L837-N866 WeakPolarHBondContact CD2-ND2 3.37Å
838M79.3Confident83.7Confident80 Ų8050.1 Ų50.139%0.39429%0.293SS..EExtended strand (participates in β ladder)trans-100.7142.4179.7-66.3-69.4-69.900109.1T611 F836 G842 N866T611-M838 HydrophobicContact CG2-CB 3.83Å; F836-M838 PolarHBondContact O-N 2.89Å; M838-G842 CarbonylContact C-O 3.51Å; M838-G842 WeakPolarHBondContact CA-O 3.32Å; M838-N866 PolarHBondContact O-ND2 2.83Å
839G77.6Confident84.1Confident1 Ų146.4 Ų46.41%0.0128%0.279CS..EExtended strand (participates in β ladder)trans-130-169.6166.200000110.1D609 S841 G842D609-G839 CarbonylContact O-C 3.59Å; D609-G839 VanDerWaalsContact O-C 3.27Å; D609-G839 WeakPolarHBondContact O-CA 3.38Å; G839-S841 PolarHBondContact O-N 3.21Å; G839-G842 PolarHBondContact N-O 3.29Å; G839-G842 PolarHBondContact O-N 3.33Å; G839-G842 VanDerWaalsContact O-N 3.08Å
840G66Low84.4Confident44 Ų4445.1 Ų45.145%0.45427%0.274SS..THydrogen-bonded Turntrans-65.1-15.9-171.600000116.6A608 C864A608-G840 WeakPolarHBondContact O-CA 3.37Å; G840-C864 PolarHBondContact N-O 3.19Å
841S71.6Confident84.7Confident106 Ų10645.7 Ų45.774%0.74128%0.276SS*.THydrogen-bonded Turntrans-113.811.6177.356.70000113.6G839G839-S841 PolarHBondContact O-N 3.21Å
842G77.9Confident85.1Confident22 Ų2242.7 Ų42.723%0.22727%0.272CS..EExtended strand (participates in β ladder)trans113.2-141.9-177.900000112.5M838 G839 Q844M838-G842 CarbonylContact C-O 3.51Å; M838-G842 WeakPolarHBondContact CA-O 3.32Å; G839-G842 PolarHBondContact N-O 3.29Å; G839-G842 PolarHBondContact O-N 3.33Å; G839-G842 VanDerWaalsContact O-N 3.08Å; G842-Q844 PolarHBondContact O-N 3.34Å
843L83.5Confident85.4Confident114 Ų11444 Ų4460%0.59726%0.259SS*.EExtended strand (participates in β ladder)trans-64.4114.9-177.8-167.189.1000110.8F836F836-L843 HydrophobicContact CB-CD1 4.49Å; F836-L843 HydrophobicContact CD1-CD1 4.32Å
844Q85.1Confident85.1Confident50 Ų5047.2 Ų47.223%0.23428%0.275CS..  trans-141.6114.4-177.1-179.161.760.200110.2L837 G842 I865 N866L837-Q844 WeakPolarHBondContact CB-O 3.29Å; L837-Q844 CarbonylContact O-C 3.53Å; L837-Q844 PolarHBondContact O-N 3.48Å; G842-Q844 PolarHBondContact O-N 3.34Å; Q844-I865 WeakPolarHBondContact CG-O 3.22Å; Q844-N866 PolarHBondContact O-ND2 2.99Å
845K89.9Confident84.1Confident77 Ų7750.8 Ų50.834%0.33530%0.3SS..  trans-68.1156.5177.5-65.9-165.5-151.2134.80112N787 E789 T847N787-K845 WeakPolarHBondContact O-CD 3.43Å; E789-K845 HydrophobicContact CG-CB 4.23Å; E789-K845 HydrophobicContact CG-CD 4.15Å; E789-K845 WeakPolarHBondContact OE1-CD 3.39Å; E789-K845 WeakPolarHBondContact OE1-CE 3.2Å; E789-K845 IonicContact OE1-NZ 2.77Å; E789-K845 PolarHBondContact OE1-NZ 2.96Å; K845-T847 PolarHBondContact O-N 3.48Å; K845-T847 PolarHBondContact O-OG1 3.2Å
846F93Very high83.5Confident2 Ų255.3 Ų55.31%0.00932%0.321CS..EExtended strand (participates in β ladder)trans-62.3129.7171.4175-102.2000110.4W784 T788 E789 F804 W805 V823 L837 I848 N866 L868W784-F846 AromaticContact CD1-CD1 3.98Å; W784-F846 HydrophobicContact CZ2-CD2 4.12Å; W784-F846 AromaticContact CZ2-CE2 3.91Å; W784-F846 HydrophobicContact CZ2-CE2 3.91Å; W784-F846 HydrophobicContact CZ2-CZ 4.28Å; W784-F846 AromaticContact NE1-CD1 3.37Å; W784-F846 AromaticContact NE1-CD2 3.61Å; W784-F846 AromaticContact NE1-CE1 3.86Å; W784-F846 AromaticContact NE1-CG 3.24Å; T788-F846 CarbonylContact C-O 3.48Å; T788-F846 WeakPolarHBondContact CA-O 3.49Å; T788-F846 HydrophobicContact CG2-CD1 3.55Å; T788-F846 HydrophobicContact CG2-CE1 3.88Å; T788-F846 WeakPolarHBondContact OG1-CD1 3.41Å; E789-F846 PolarHBondContact N-O 3.47Å; F804-F846 HydrophobicContact CZ-CZ 4.37Å; W805-F846 HydrophobicContact CH2-CE1 4.23Å; W805-F846 HydrophobicContact CZ2-CE1 4.1Å; V823-F846 HydrophobicContact CB-CD2 4.29Å; V823-F846 HydrophobicContact CB-CE2 3.78Å; V823-F846 HydrophobicContact CG1-CD2 3.66Å; V823-F846 HydrophobicContact CG1-CE2 3.36Å; V823-F846 HydrophobicContact CG2-CE2 3.94Å; L837-F846 HydrophobicContact CD2-CB 4.1Å; F846-I848 HydrophobicContact CD1-CG1 4.37Å; F846-I848 HydrophobicContact CE1-CD1 3.83Å; F846-I848 HydrophobicContact CE1-CG1 3.56Å; F846-I848 HydrophobicContact CZ-CD1 4.33Å; F846-I848 HydrophobicContact CZ-CG1 4Å; F846-N866 WeakPolarHBondContact CA-O 3.34Å; F846-L868 HydrophobicContact CE2-CB 4.29Å; F846-L868 HydrophobicContact CZ-CB 4.15Å; F846-L868 HydrophobicContact CZ-CD2 4.28Å
847T93.2Very high83.2Confident10 Ų1052.8 Ų52.86%0.06131%0.312CS..EExtended strand (participates in β ladder)trans-124.4134.6-173.2-55.40000111.3E789 T791 K845 N866 M867 L868E789-T847 CarbonylContact O-C 3.19Å; E789-T847 VanDerWaalsContact O-CA 3.24Å; E789-T847 WeakPolarHBondContact O-CA 3.33Å; T791-T847 HydrophobicContact CG2-CG2 3.68Å; T791-T847 WeakPolarHBondContact OG1-CG2 3.42Å; K845-T847 PolarHBondContact O-N 3.48Å; K845-T847 PolarHBondContact O-OG1 3.2Å; T847-N866 PolarHBondContact N-O 3.28Å; T847-M867 HydrophobicContact CG2-CG 4.34Å; T847-M867 CarbonylContact O-C 3.53Å; T847-M867 VanDerWaalsContact O-CA 3.32Å; T847-M867 WeakPolarHBondContact O-CA 3.43Å; T847-L868 PolarHBondContact O-N 2.89Å
848I95.4Very high83.2Confident0 Ų053.8 Ų53.80%032%0.317CS..EExtended strand (participates in β ladder)trans-109.3125.9171.1-52.5-174000109.8T788 E789 Y790 T791 Y794 I801 F804 F846 L868 L870T788-I848 HydrophobicContact CG2-CD1 4.22Å; T788-I848 HydrophobicContact CG2-CG1 3.99Å; E789-I848 PolarHBondContact O-N 3.41Å; Y790-I848 WeakPolarHBondContact CA-O 3.41Å; Y790-I848 HydrophobicContact CD1-CB 4.05Å; Y790-I848 HydrophobicContact CE1-CB 4.35Å; Y790-I848 HydrophobicContact CE1-CD1 3.98Å; Y790-I848 HydrophobicContact CE1-CG1 4.38Å; T791-I848 PolarHBondContact N-O 2.97Å; T791-I848 PolarHBondContact OG1-O 3.24Å; Y794-I848 HydrophobicContact CD2-CG2 4.03Å; Y794-I848 HydrophobicContact CE2-CG2 4.3Å; I801-I848 HydrophobicContact CD1-CB 4.47Å; I801-I848 HydrophobicContact CD1-CD1 4.32Å; I801-I848 HydrophobicContact CD1-CG2 3.9Å; F804-I848 HydrophobicContact CD1-CD1 3.74Å; F804-I848 HydrophobicContact CE1-CD1 3.63Å; F804-I848 HydrophobicContact CG-CD1 4.47Å; F804-I848 HydrophobicContact CZ-CD1 4.28Å; F846-I848 HydrophobicContact CD1-CG1 4.37Å; F846-I848 HydrophobicContact CE1-CD1 3.83Å; F846-I848 HydrophobicContact CE1-CG1 3.56Å; F846-I848 HydrophobicContact CZ-CD1 4.33Å; F846-I848 HydrophobicContact CZ-CG1 4Å; I848-L868 CarbonylContact C-O 3.59Å; I848-L868 WeakPolarHBondContact CA-O 3.33Å; I848-L870 HydrophobicContact CG2-CB 3.86Å; I848-L870 HydrophobicContact CG2-CD2 4.17Å
849A93.2Very high83.7Confident4 Ų450.1 Ų50.13%0.03330%0.299CS..EExtended strand (participates in β ladder)trans-114.6134.7178.600000111.5T791 M867 L868 L870T791-A849 WeakPolarHBondContact O-CA 3.45Å; A849-M867 HydrophobicContact CB-CG 4.32Å; A849-M867 HydrophobicContact CB-SD 4.05Å; A849-L868 PolarHBondContact N-O 2.85Å; A849-L870 PolarHBondContact O-N 3.31Å
850A90.3Very high84Confident16 Ų1653.4 Ų53.413%0.13232%0.319CS..EExtended strand (participates in β ladder)trans-71.1141.7174.900000112.8T791 S792 Y794T791-A850 PolarHBondContact O-N 3.43Å; S792-A850 WeakPolarHBondContact O-CB 3.32Å; Y794-A850 HydrophobicContact CD1-CB 4.14Å; Y794-A850 HydrophobicContact CD2-CB 3.54Å; Y794-A850 HydrophobicContact CE1-CB 4.06Å; Y794-A850 HydrophobicContact CE2-CB 3.48Å; Y794-A850 VanDerWaalsContact CE2-CB 3.48Å; Y794-A850 HydrophobicContact CG-CB 3.86Å
851V89.1Confident84.9Confident36 Ų3653 Ų5322%0.21831%0.309CS..EExtended strand (participates in β ladder)trans-132.5135.9173.4-176.60000109.2Y853 L857 K869 L870 P871 E872V851-Y853 PolarHBondContact O-N 3.46Å; V851-L857 HydrophobicContact CG1-CD2 3.78Å; V851-K869 HydrophobicContact CG2-CB 3.77Å; V851-L870 PolarHBondContact N-O 3.16Å; V851-P871 VanDerWaalsContact O-CA 3.27Å; V851-P871 WeakPolarHBondContact O-CA 3.36Å; V851-E872 PolarHBondContact O-N 2.75Å
852P85.4Confident85.5Confident104 Ų10449.6 Ų49.668%0.67529%0.286SS*.  trans-56.4131.1175.2-2634.7000112.3
853Y83.8Confident85.6Confident87 Ų8749.7 Ų49.734%0.34128%0.282SS..  trans-71.5135.3-178172.8-104.2000113V851 P871 E872 Y873V851-Y853 PolarHBondContact O-N 3.46Å; Y853-P871 HydrophobicContact CD2-CB 4.46Å; Y853-E872 WeakPolarHBondContact CB-O 3.36Å; Y853-Y873 AromaticContact CD2-CD1 3.72Å; Y853-Y873 HydrophobicContact CD2-CD1 3.72Å; Y853-Y873 HydrophobicContact CD2-CE1 4.01Å; Y853-Y873 AromaticContact CE2-CD1 3.64Å; Y853-Y873 HydrophobicContact CE2-CD1 3.64Å; Y853-Y873 AromaticContact CE2-CE1 3.91Å; Y853-Y873 HydrophobicContact CE2-CE1 3.91Å
854T80.7Confident85.2Confident83 Ų8345.3 Ų45.351%0.50926%0.26SS..  trans-134.5150.4165.836.30000109.2N856 L857T854-N856 PolarHBondContact O-N 3.49Å; T854-L857 PolarHBondContact O-N 3.32Å; T854-L857 VanDerWaalsContact O-N 3.09Å; T854-L857 WeakPolarHBondContact OG1-CB 3.34Å
855S70.4Confident85Confident78 Ų7846.4 Ų46.455%0.54527%0.267SS..THydrogen-bonded Turntrans-57.2-18.6-163.746.30000116.2R882S855-R882 PolarHBondContact O-NH2 3.15Å
856N74.9Confident84.8Confident127 Ų12742.8 Ų42.868%0.67925%0.252SS*.THydrogen-bonded Turntrans-124.49.8-176.9-65.3-26.9000114.3T854 L858T854-N856 PolarHBondContact O-N 3.49Å; N856-L858 PolarHBondContact O-N 2.77Å
857L81.4Confident84.6Confident60 Ų6044.3 Ų44.331%0.31426%0.259SS..PPolyproline II helixtrans-81.3122.1-176.5-165.665.3000111V851 T854 P871 Y873V851-L857 HydrophobicContact CG1-CD2 3.78Å; T854-L857 PolarHBondContact O-N 3.32Å; T854-L857 VanDerWaalsContact O-N 3.09Å; T854-L857 WeakPolarHBondContact OG1-CB 3.34Å; L857-P871 HydrophobicContact CB-CG 4.42Å; L857-P871 HydrophobicContact CD2-CB 4.5Å; L857-P871 HydrophobicContact CD2-CG 3.95Å; L857-P871 HydrophobicContact CG-CG 4.07Å; L857-Y873 PolarHBondContact O-OH 2.96Å
858L86.1Confident84.6Confident28 Ų2843.8 Ų43.815%0.14726%0.256CS..PPolyproline II helixtrans-84.1153.2170.9-64.4178.4000110.2N856 R882 V885 A886N856-L858 PolarHBondContact O-N 2.77Å; L858-R882 HydrophobicContact CD2-CB 4.25Å; L858-V885 HydrophobicContact CD1-CG1 4.2Å; L858-V885 HydrophobicContact CD2-CB 4.2Å; L858-V885 HydrophobicContact CD2-CG1 3.84Å; L858-A886 HydrophobicContact CB-CB 4.22Å
859P88.3Confident84.4Confident3 Ų347.3 Ų47.32%0.01927%0.271CS..PPolyproline II helixtrans-61.3146.4167.729.2-35.2000110.1L868 K869 L870 Y873 L883 A886P859-L868 HydrophobicContact CB-CD1 4.17Å; P859-K869 WeakPolarHBondContact CA-O 3.48Å; P859-L870 HydrophobicContact CB-CD1 4.25Å; P859-Y873 VanDerWaalsContact CD-OH 3.23Å; P859-Y873 WeakPolarHBondContact CD-OH 3.48Å; P859-L883 HydrophobicContact CG-CD1 4.02Å; P859-A886 HydrophobicContact CG-CB 3.52Å
860T85.4Confident84.3Confident70 Ų7047.1 Ų47.143%0.42927%0.27SS..EExtended strand (participates in β ladder)trans-127.3158.1179.251.70000109.8K869T860-K869 PolarHBondContact N-O 2.87Å; T860-K869 VanDerWaalsContact N-O 3.14Å; T860-K869 WeakPolarHBondContact O-CB 3.38Å; T860-K869 PolarHBondContact O-N 3.22Å; T860-K869 WeakPolarHBondContact OG1-CB 3.31Å
861S85.1Confident84.4Confident36 Ų3646.4 Ų46.425%0.25226%0.264SS..EExtended strand (participates in β ladder)trans-123.3165.1-178.962.30000112.8F822 M867F822-S861 WeakPolarHBondContact O-CB 3.42Å; F822-S861 PolarHBondContact O-OG 3.33Å; S861-M867 CarbonylContact C-O 3.59Å; S861-M867 VanDerWaalsContact CA-O 3.27Å; S861-M867 WeakPolarHBondContact CA-O 3.46Å
862S83.1Confident84.5Confident35 Ų3549.6 Ų49.625%0.24528%0.276CS..EExtended strand (participates in β ladder)trans-137.694.3169.3-61.20000107.7C864 I865 N866 M867S862-C864 PolarHBondContact O-N 2.72Å; S862-I865 WeakPolarHBondContact O-CG1 3.21Å; S862-I865 PolarHBondContact O-N 2.94Å; S862-N866 PolarHBondContact O-N 3.41Å; S862-M867 PolarHBondContact N-O 2.82Å; S862-M867 PolarHBondContact O-N 3.42Å; S862-M867 VanDerWaalsContact O-N 3.16Å
863T80.3Confident84.8Confident24 Ų2444.8 Ų44.815%0.14725%0.245CC..G310 helixtrans-62.7-37.7-168.153.60000113.4V823 I865 N866V823-T863 VanDerWaalsContact O-CA 3.31Å; V823-T863 WeakPolarHBondContact O-CA 3.43Å; T863-I865 PolarHBondContact O-N 3.47Å; T863-N866 PolarHBondContact O-N 3.23Å; T863-N866 VanDerWaalsContact O-N 3.07Å; T863-N866 PolarHBondContact O-OD1 3.32Å
864C74.4Confident85Confident21 Ų2144.3 Ų44.314%0.14225%0.252CS..G310 helixtrans-61.1-19.9179.7-44.40000114.1P673 G840 S862P673-C864 HydrophobicContact CG-CB 4.35Å; P673-C864 WeakPolarHBondContact CG-SG 3.21Å; G840-C864 PolarHBondContact N-O 3.19Å; S862-C864 PolarHBondContact O-N 2.72Å
865I81.1Confident85.6Confident73 Ų7343.4 Ų43.437%0.37424%0.244SC..G310 helixtrans-124.115.6178.856.9168.3000112.3Q844 S862 T863 M867Q844-I865 WeakPolarHBondContact CG-O 3.22Å; S862-I865 WeakPolarHBondContact O-CG1 3.21Å; S862-I865 PolarHBondContact O-N 2.94Å; T863-I865 PolarHBondContact O-N 3.47Å; I865-M867 HydrophobicContact CD1-CB 3.97Å; I865-M867 HydrophobicContact CD1-CE 3.67Å; I865-M867 HydrophobicContact CD1-SD 3.99Å; I865-M867 HydrophobicContact CG1-CB 3.84Å; I865-M867 PolarHBondContact O-N 3.02Å; I865-M867 VanDerWaalsContact O-N 3.15Å
866N87Confident86.6Confident2 Ų241.7 Ų41.71%0.01123%0.228CC..THydrogen-bonded Turntrans5039.9178.7-59.8-36.7000113.4T824 L837 M838 Q844 F846 T847 S862 T863T824-N866 HydrophobicContact CG2-CB 4.5Å; L837-N866 HydrophobicContact CD2-CB 3.83Å; L837-N866 WeakPolarHBondContact CD2-ND2 3.37Å; M838-N866 PolarHBondContact O-ND2 2.83Å; Q844-N866 PolarHBondContact O-ND2 2.99Å; F846-N866 WeakPolarHBondContact CA-O 3.34Å; T847-N866 PolarHBondContact N-O 3.28Å; S862-N866 PolarHBondContact O-N 3.41Å; T863-N866 PolarHBondContact O-N 3.23Å; T863-N866 VanDerWaalsContact O-N 3.07Å; T863-N866 PolarHBondContact O-OD1 3.32Å
867M88.4Confident87.3Confident33 Ų3343.4 Ų43.416%0.16323%0.232CC..EExtended strand (participates in β ladder)trans-109.9127.6-171-173.4176.868.700112.5T847 A849 S861 S862 I865 K869T847-M867 HydrophobicContact CG2-CG 4.34Å; T847-M867 CarbonylContact O-C 3.53Å; T847-M867 VanDerWaalsContact O-CA 3.32Å; T847-M867 WeakPolarHBondContact O-CA 3.43Å; A849-M867 HydrophobicContact CB-CG 4.32Å; A849-M867 HydrophobicContact CB-SD 4.05Å; S861-M867 CarbonylContact C-O 3.59Å; S861-M867 VanDerWaalsContact CA-O 3.27Å; S861-M867 WeakPolarHBondContact CA-O 3.46Å; S862-M867 PolarHBondContact N-O 2.82Å; S862-M867 PolarHBondContact O-N 3.42Å; S862-M867 VanDerWaalsContact O-N 3.16Å; I865-M867 HydrophobicContact CD1-CB 3.97Å; I865-M867 HydrophobicContact CD1-CE 3.67Å; I865-M867 HydrophobicContact CD1-SD 3.99Å; I865-M867 HydrophobicContact CG1-CB 3.84Å; I865-M867 PolarHBondContact O-N 3.02Å; I865-M867 VanDerWaalsContact O-N 3.15Å; M867-K869 HydrophobicContact CE-CD 4.4Å; M867-K869 VanDerWaalsContact CE-CE 3.45Å; M867-K869 HydrophobicContact CE-CG 4.07Å
868L92.3Very high87.7Confident0 Ų042.3 Ų42.30%023%0.227CC..EExtended strand (participates in β ladder)trans-100.2119.8169.8-179.766.6000109.9F804 F822 V823 F846 T847 I848 A849 P859 L870F804-L868 HydrophobicContact CD2-CD2 4.38Å; F804-L868 HydrophobicContact CE2-CD2 3.53Å; F804-L868 HydrophobicContact CZ-CD2 3.68Å; F822-L868 HydrophobicContact CD1-CD1 4.32Å; F822-L868 HydrophobicContact CE1-CD1 3.92Å; V823-L868 HydrophobicContact CG1-CB 4.17Å; V823-L868 HydrophobicContact CG2-CB 4.07Å; V823-L868 HydrophobicContact CG2-CD1 3.93Å; V823-L868 HydrophobicContact CG2-CG 4.45Å; F846-L868 HydrophobicContact CE2-CB 4.29Å; F846-L868 HydrophobicContact CZ-CB 4.15Å; F846-L868 HydrophobicContact CZ-CD2 4.28Å; T847-L868 PolarHBondContact O-N 2.89Å; I848-L868 CarbonylContact C-O 3.59Å; I848-L868 WeakPolarHBondContact CA-O 3.33Å; A849-L868 PolarHBondContact N-O 2.85Å; P859-L868 HydrophobicContact CB-CD1 4.17Å; L868-L870 HydrophobicContact CG-CB 4.49Å
869K90.8Very high88Confident74 Ų7441 Ų4132%0.32222%0.22SC..EExtended strand (participates in β ladder)trans-91.1105.6171.8-64.6177.8-173.7171.50108.4V851 P859 T860 M867V851-K869 HydrophobicContact CG2-CB 3.77Å; P859-K869 WeakPolarHBondContact CA-O 3.48Å; T860-K869 PolarHBondContact N-O 2.87Å; T860-K869 VanDerWaalsContact N-O 3.14Å; T860-K869 WeakPolarHBondContact O-CB 3.38Å; T860-K869 PolarHBondContact O-N 3.22Å; T860-K869 WeakPolarHBondContact OG1-CB 3.31Å; M867-K869 HydrophobicContact CE-CD 4.4Å; M867-K869 VanDerWaalsContact CE-CE 3.45Å; M867-K869 HydrophobicContact CE-CG 4.07Å
870L92.3Very high88.2Confident0 Ų045.4 Ų45.40%024%0.237CC..EExtended strand (participates in β ladder)trans-109.6115.4-171.5-175.367.7000110.8Y794 V800 I801 F804 I848 A849 V851 P859 L868 Y873Y794-L870 HydrophobicContact CE2-CB 4.12Å; Y794-L870 VanDerWaalsContact CE2-O 3.32Å; Y794-L870 WeakPolarHBondContact CE2-O 3.19Å; Y794-L870 PolarHBondContact OH-O 3.13Å; V800-L870 HydrophobicContact CG1-CD2 3.97Å; V800-L870 HydrophobicContact CG1-CG 4.42Å; I801-L870 HydrophobicContact CD1-CD2 4.45Å; F804-L870 HydrophobicContact CB-CD2 4.13Å; F804-L870 HydrophobicContact CD2-CD2 4.12Å; F804-L870 HydrophobicContact CG-CD2 4.25Å; I848-L870 HydrophobicContact CG2-CB 3.86Å; I848-L870 HydrophobicContact CG2-CD2 4.17Å; A849-L870 PolarHBondContact O-N 3.31Å; V851-L870 PolarHBondContact N-O 3.16Å; P859-L870 HydrophobicContact CB-CD1 4.25Å; L868-L870 HydrophobicContact CG-CB 4.49Å; L870-Y873 HydrophobicContact CD1-CD2 4.33Å; L870-Y873 HydrophobicContact CD1-CE2 3.99Å
871P92.3Very high88.3Confident1 Ų146.2 Ų46.21%0.00624%0.238CC..EExtended strand (participates in β ladder)trans-61.4148.3174.9-25.736000113.2Y794 V851 Y853 L857 Y873Y794-P871 VanDerWaalsContact OH-C 3.29Å; Y794-P871 PolarHBondContact OH-O 3.15Å; V851-P871 VanDerWaalsContact O-CA 3.27Å; V851-P871 WeakPolarHBondContact O-CA 3.36Å; Y853-P871 HydrophobicContact CD2-CB 4.46Å; L857-P871 HydrophobicContact CB-CG 4.42Å; L857-P871 HydrophobicContact CD2-CB 4.5Å; L857-P871 HydrophobicContact CD2-CG 3.95Å; L857-P871 HydrophobicContact CG-CG 4.07Å; P871-Y873 HydrophobicContact CB-CD1 4.44Å; P871-Y873 HydrophobicContact CB-CD2 4.45Å; P871-Y873 HydrophobicContact CB-CE1 3.97Å; P871-Y873 HydrophobicContact CB-CE2 4.03Å; P871-Y873 HydrophobicContact CG-CE1 4.37Å; P871-Y873 HydrophobicContact CG-CE2 4.17Å; P871-Y873 WeakPolarHBondContact CG-OH 3.43Å; P871-Y873 VanDerWaalsContact O-CD2 3.26Å; P871-Y873 WeakPolarHBondContact O-CD2 3.48Å; P871-Y873 PolarHBondContact O-N 3.08Å
872E90.4Very high88.4Confident102 Ų10247.5 Ų47.548%0.47724%0.238SC..  trans-71.370.4176.3-68.5176.5177.500111.6Y794 V851 Y853Y794-E872 HydrophobicContact CE1-CG 4.04Å; Y794-E872 WeakPolarHBondContact OH-CA 3.27Å; Y794-E872 WeakPolarHBondContact OH-CG 3.39Å; Y794-E872 PolarHBondContact OH-N 2.6Å; V851-E872 PolarHBondContact O-N 2.75Å; Y853-E872 WeakPolarHBondContact CB-O 3.36Å
873Y91.4Very high88.8Confident4 Ų445.9 Ų45.92%0.01623%0.226CC..  trans-62.2144.4-174.8-70.4-61.5000112.4W803 Y853 L857 P859 L870 P871 N875 V878 L879 R882W803-Y873 WeakPolarHBondContact CZ3-O 3.45Å; Y853-Y873 AromaticContact CD2-CD1 3.72Å; Y853-Y873 HydrophobicContact CD2-CD1 3.72Å; Y853-Y873 HydrophobicContact CD2-CE1 4.01Å; Y853-Y873 AromaticContact CE2-CD1 3.64Å; Y853-Y873 HydrophobicContact CE2-CD1 3.64Å; Y853-Y873 AromaticContact CE2-CE1 3.91Å; Y853-Y873 HydrophobicContact CE2-CE1 3.91Å; L857-Y873 PolarHBondContact O-OH 2.96Å; P859-Y873 VanDerWaalsContact CD-OH 3.23Å; P859-Y873 WeakPolarHBondContact CD-OH 3.48Å; L870-Y873 HydrophobicContact CD1-CD2 4.33Å; L870-Y873 HydrophobicContact CD1-CE2 3.99Å; P871-Y873 HydrophobicContact CB-CD1 4.44Å; P871-Y873 HydrophobicContact CB-CD2 4.45Å; P871-Y873 HydrophobicContact CB-CE1 3.97Å; P871-Y873 HydrophobicContact CB-CE2 4.03Å; P871-Y873 HydrophobicContact CG-CE1 4.37Å; P871-Y873 HydrophobicContact CG-CE2 4.17Å; P871-Y873 WeakPolarHBondContact CG-OH 3.43Å; P871-Y873 VanDerWaalsContact O-CD2 3.26Å; P871-Y873 WeakPolarHBondContact O-CD2 3.48Å; P871-Y873 PolarHBondContact O-N 3.08Å; Y873-N875 VanDerWaalsContact C-N 3.33Å; Y873-N875 PolarHBondContact O-N 2.85Å; Y873-V878 HydrophobicContact CD1-CG1 3.84Å; Y873-V878 HydrophobicContact CE1-CG1 4.45Å; Y873-V878 HydrophobicContact CG-CG1 4.5Å; Y873-L879 HydrophobicContact CD2-CB 3.88Å; Y873-L879 HydrophobicContact CD2-CD1 4.19Å; Y873-L879 HydrophobicContact CD2-CG 3.83Å; Y873-L879 HydrophobicContact CG-CB 4.19Å; Y873-R882 HydrophobicContact CE1-CB 3.98Å; Y873-R882 HydrophobicContact CE1-CG 3.83Å; Y873-R882 HydrophobicContact CE2-CB 4.39Å
874P89.4Confident89Confident76 Ų7646.1 Ų46.149%0.49423%0.226SC..SBendtrans-73.4-22.2-173.828.5-35.7000113.9
875N92.1Very high89.5Confident64 Ų6447.4 Ų47.434%0.34223%0.234SC..SBendtrans-157.2167.5178.765.158.3000112.5Y873 E877 V878 L879Y873-N875 VanDerWaalsContact C-N 3.33Å; Y873-N875 PolarHBondContact O-N 2.85Å; N875-E877 PolarHBondContact O-N 3.29Å; N875-E877 PolarHBondContact OD1-N 3.04Å; N875-E877 VanDerWaalsContact OD1-N 3.11Å; N875-V878 WeakPolarHBondContact OD1-CG2 3.47Å; N875-V878 PolarHBondContact OD1-N 2.99Å; N875-L879 PolarHBondContact O-N 3.35Å; N875-L879 VanDerWaalsContact O-N 3.14Å
876Q92.1Very high89.6Confident43 Ų4344.1 Ų44.120%0.20122%0.217CC..Hα-helixtrans-63.4-35-177.5-173.5-176.1-21.400113.5W803 V807 R880W803-Q876 HydrophobicContact CB-CB 4.21Å; W803-Q876 HydrophobicContact CB-CG 4.08Å; W803-Q876 HydrophobicContact CD2-CB 4.14Å; W803-Q876 HydrophobicContact CG-CB 3.85Å; W803-Q876 HydrophobicContact CG-CG 4.17Å; V807-Q876 HydrophobicContact CG2-CG 4.01Å; Q876-R880 WeakPolarHBondContact O-CB 3.38Å; Q876-R880 PolarHBondContact O-N 3.29Å
877E90.4Very high89.4Confident163 Ų16344.4 Ų44.476%0.76222%0.219SC*.Hα-helixtrans-70.7-44.5-177.1-68.4177.8-179.800111.3N875 L879 R880 D881N875-E877 PolarHBondContact O-N 3.29Å; N875-E877 PolarHBondContact OD1-N 3.04Å; N875-E877 VanDerWaalsContact OD1-N 3.11Å; E877-L879 VanDerWaalsContact C-N 3.35Å; E877-R880 PolarHBondContact O-N 3.31Å; E877-D881 WeakPolarHBondContact O-CB 3.29Å; E877-D881 PolarHBondContact O-N 2.93Å
878V89.3Confident88.6Confident37 Ų3747 Ų4722%0.22423%0.23CC..Hα-helixtrans-63.3-42.1174.5175.20000110.5Y873 N875 R880 D881 R882Y873-V878 HydrophobicContact CD1-CG1 3.84Å; Y873-V878 HydrophobicContact CE1-CG1 4.45Å; Y873-V878 HydrophobicContact CG-CG1 4.5Å; N875-V878 WeakPolarHBondContact OD1-CG2 3.47Å; N875-V878 PolarHBondContact OD1-N 2.99Å; V878-R880 VanDerWaalsContact C-N 3.34Å; V878-R880 PolarHBondContact O-N 2.76Å; V878-D881 PolarHBondContact O-N 3.48Å; V878-R882 HydrophobicContact CG1-CG 4.04Å; V878-R882 WeakPolarHBondContact O-CB 3.42Å; V878-R882 VanDerWaalsContact O-CG 3.25Å; V878-R882 WeakPolarHBondContact O-CG 3.29Å; V878-R882 PolarHBondContact O-N 2.92Å
879L92.1Very high87.3Confident0 Ų049.8 Ų49.80%025%0.249CC..Hα-helixtrans-58.1-48.2174.7-175.3156.3000111V800 W803 F804 V807 Y873 N875 E877 L883V800-L879 HydrophobicContact CG1-CD1 3.89Å; W803-L879 HydrophobicContact CB-CD1 4.15Å; F804-L879 HydrophobicContact CB-CD1 4.33Å; V807-L879 HydrophobicContact CB-CD2 4.3Å; V807-L879 HydrophobicContact CG2-CD2 4.07Å; Y873-L879 HydrophobicContact CD2-CB 3.88Å; Y873-L879 HydrophobicContact CD2-CD1 4.19Å; Y873-L879 HydrophobicContact CD2-CG 3.83Å; Y873-L879 HydrophobicContact CG-CB 4.19Å; N875-L879 PolarHBondContact O-N 3.35Å; N875-L879 VanDerWaalsContact O-N 3.14Å; E877-L879 VanDerWaalsContact C-N 3.35Å; L879-L883 HydrophobicContact CD2-CD2 4.44Å; L879-L883 WeakPolarHBondContact O-CB 3.37Å; L879-L883 PolarHBondContact O-N 3.04Å
880R91.9Very high85.5Confident96 Ų9647.7 Ų47.736%0.36225%0.248SC..Hα-helixtrans-59.8-50.5179.3179.5-176.2175.7128.77.6111.3V807 Q876 E877 V878 L883 L884V807-R880 HydrophobicContact CG1-CB 4.18Å; V807-R880 HydrophobicContact CG1-CG 4.07Å; V807-R880 HydrophobicContact CG2-CB 3.97Å; Q876-R880 WeakPolarHBondContact O-CB 3.38Å; Q876-R880 PolarHBondContact O-N 3.29Å; E877-R880 PolarHBondContact O-N 3.31Å; V878-R880 VanDerWaalsContact C-N 3.34Å; V878-R880 PolarHBondContact O-N 2.76Å; R880-L883 PolarHBondContact O-N 2.9Å; R880-L884 HydrophobicContact CG-CD1 3.99Å; R880-L884 WeakPolarHBondContact O-CG 3.41Å; R880-L884 PolarHBondContact O-N 3.48Å
881D88.3Confident83.3Confident87 Ų8748.1 Ų48.147%0.46525%0.251SS..Hα-helixtrans-59.3-53.2-179-18068.4000111.2E877 V878 L883 L884 V885E877-D881 WeakPolarHBondContact O-CB 3.29Å; E877-D881 PolarHBondContact O-N 2.93Å; V878-D881 PolarHBondContact O-N 3.48Å; D881-L883 VanDerWaalsContact C-N 3.32Å; D881-L883 PolarHBondContact O-N 3.13Å; D881-L884 PolarHBondContact O-N 2.99Å; D881-V885 WeakPolarHBondContact O-CB 3.44Å; D881-V885 VanDerWaalsContact O-CG2 3.27Å; D881-V885 WeakPolarHBondContact O-CG2 3.45Å; D881-V885 PolarHBondContact O-N 3.46Å
882R88.1Confident81Confident63 Ų6353.1 Ų53.124%0.23827%0.27CS..Hα-helixtrans-65-34.4-179.7-62.2-52.2-166.1-179.37.3113S855 L858 Y873 V878 A886S855-R882 PolarHBondContact O-NH2 3.15Å; L858-R882 HydrophobicContact CD2-CB 4.25Å; Y873-R882 HydrophobicContact CE1-CB 3.98Å; Y873-R882 HydrophobicContact CE1-CG 3.83Å; Y873-R882 HydrophobicContact CE2-CB 4.39Å; V878-R882 HydrophobicContact CG1-CG 4.04Å; V878-R882 WeakPolarHBondContact O-CB 3.42Å; V878-R882 VanDerWaalsContact O-CG 3.25Å; V878-R882 WeakPolarHBondContact O-CG 3.29Å; V878-R882 PolarHBondContact O-N 2.92Å; R882-A886 WeakPolarHBondContact O-CB 3.28Å; R882-A886 PolarHBondContact O-N 3.29Å
883L89.6Confident78.4Confident0 Ų049.2 Ų49.20%026%0.258CS..Hα-helixtrans-65.4-50.4174.7-176.864.4000110.9F804 V807 L819 P859 L879 R880 D881 V885 A886 L887F804-L883 HydrophobicContact CD2-CD2 4.28Å; F804-L883 HydrophobicContact CE2-CD1 4.48Å; F804-L883 HydrophobicContact CE2-CD2 4.1Å; V807-L883 HydrophobicContact CG1-CD2 4.18Å; L819-L883 HydrophobicContact CD1-CD1 4.14Å; P859-L883 HydrophobicContact CG-CD1 4.02Å; L879-L883 HydrophobicContact CD2-CD2 4.44Å; L879-L883 WeakPolarHBondContact O-CB 3.37Å; L879-L883 PolarHBondContact O-N 3.04Å; R880-L883 PolarHBondContact O-N 2.9Å; D881-L883 VanDerWaalsContact C-N 3.32Å; D881-L883 PolarHBondContact O-N 3.13Å; L883-V885 VanDerWaalsContact C-N 3.33Å; L883-V885 PolarHBondContact O-N 3.49Å; L883-A886 PolarHBondContact O-N 3.39Å; L883-A886 VanDerWaalsContact O-N 3.12Å; L883-L887 HydrophobicContact CG-CD1 4.39Å; L883-L887 WeakPolarHBondContact O-CG 3.5Å; L883-L887 PolarHBondContact O-N 3.35Å
884L85.6Confident75.6Confident29 Ų2958.6 Ų58.615%0.15230%0.295CS..Hα-helixtrans-61.5-42.4178.3-71.3174000111.6L811 E815 R880 D881 A886 L887 H888L811-L884 HydrophobicContact CD2-CD2 3.84Å; E815-L884 HydrophobicContact CG-CD2 4.31Å; R880-L884 HydrophobicContact CG-CD1 3.99Å; R880-L884 WeakPolarHBondContact O-CG 3.41Å; R880-L884 PolarHBondContact O-N 3.48Å; D881-L884 PolarHBondContact O-N 2.99Å; L884-A886 VanDerWaalsContact C-N 3.32Å; L884-A886 PolarHBondContact O-N 2.75Å; L884-L887 PolarHBondContact O-N 3.03Å; L884-H888 PolarHBondContact O-CD2 3.25Å; L884-H888 PolarHBondContact O-N 2.7Å
885V84.3Confident72.7Confident49 Ų4960.8 Ų60.830%0.29731%0.307SS..Hα-helixtrans-59-43.1173.7172.30000110.8L858 D881 L883 H888 C889L858-V885 HydrophobicContact CD1-CG1 4.2Å; L858-V885 HydrophobicContact CD2-CB 4.2Å; L858-V885 HydrophobicContact CD2-CG1 3.84Å; D881-V885 WeakPolarHBondContact O-CB 3.44Å; D881-V885 VanDerWaalsContact O-CG2 3.27Å; D881-V885 WeakPolarHBondContact O-CG2 3.45Å; D881-V885 PolarHBondContact O-N 3.46Å; L883-V885 VanDerWaalsContact C-N 3.33Å; L883-V885 PolarHBondContact O-N 3.49Å; V885-H888 PolarHBondContact O-N 3.44Å; V885-C889 WeakPolarHBondContact O-CB 3.33Å; V885-C889 PolarHBondContact O-N 3.34Å; V885-C889 PolarHBondContact O-SG 3.12Å
886A83.7Confident69.6Low4 Ų466.5 Ų66.53%0.03333%0.334CS..Hα-helixtrans-66.6-37.2177.700000113.4F822 L858 P859 R882 L883 L884 G890F822-A886 HydrophobicContact CZ-CB 4.47Å; L858-A886 HydrophobicContact CB-CB 4.22Å; P859-A886 HydrophobicContact CG-CB 3.52Å; R882-A886 WeakPolarHBondContact O-CB 3.28Å; R882-A886 PolarHBondContact O-N 3.29Å; L883-A886 PolarHBondContact O-N 3.39Å; L883-A886 VanDerWaalsContact O-N 3.12Å; L884-A886 VanDerWaalsContact C-N 3.32Å; L884-A886 PolarHBondContact O-N 2.75Å; A886-G890 WeakPolarHBondContact O-CA 3.32Å; A886-G890 PolarHBondContact O-N 3.24Å
887L82.3Confident66.4Low7 Ų772.8 Ų72.84%0.03739%0.393CS..Hα-helixtrans-66.7-41176.4-63.6179.6000111.6L819 F822 L883 L884L819-L887 HydrophobicContact CB-CD1 4.05Å; L819-L887 HydrophobicContact CB-CD2 4.14Å; L819-L887 HydrophobicContact CD1-CD2 3.96Å; F822-L887 HydrophobicContact CB-CD2 3.62Å; F822-L887 HydrophobicContact CD1-CD2 3.98Å; F822-L887 HydrophobicContact CD2-CD2 4.44Å; F822-L887 HydrophobicContact CG-CD2 3.77Å; L883-L887 HydrophobicContact CG-CD1 4.39Å; L883-L887 WeakPolarHBondContact O-CG 3.5Å; L883-L887 PolarHBondContact O-N 3.35Å; L884-L887 PolarHBondContact O-N 3.03Å
888H72Confident65.2Low89 Ų8968.3 Ų68.341%0.41238%0.375SS..Hα-helixtrans-80.7-28.8178.3-66.6-58.3000113.5L884 V885 S891 Y892L884-H888 PolarHBondContact O-CD2 3.25Å; L884-H888 PolarHBondContact O-N 2.7Å; V885-H888 PolarHBondContact O-N 3.44Å; H888-S891 PolarHBondContact O-OG 3.14Å; H888-Y892 WeakPolarHBondContact O-CD2 3.39Å
889C65.9Low63.9Low58 Ų5869.9 Ų69.939%0.39238%0.383SS..Hα-helixtrans-83.6-25173.7-67.90000112.2V885 S891 Y892V885-C889 WeakPolarHBondContact O-CB 3.33Å; V885-C889 PolarHBondContact O-N 3.34Å; V885-C889 PolarHBondContact O-SG 3.12Å; C889-S891 PolarHBondContact O-N 3.25Å; C889-Y892 CarbonylContact O-C 3.49Å; C889-Y892 PolarHBondContact O-N 3.12Å; C889-Y892 VanDerWaalsContact O-N 3.15Å
890G53Low62.3Low29 Ų2973.8 Ų73.830%0.29940%0.404SS..THydrogen-bonded Turntrans-63.6-21.9170.600000113Y767 A886Y767-G890 PolarHBondContact OH-O 3.17Å; A886-G890 WeakPolarHBondContact O-CA 3.32Å; A886-G890 PolarHBondContact O-N 3.24Å
891S45.8Very low60.6Low9 Ų972.5 Ų72.56%0.06341%0.406CS..THydrogen-bonded Turntrans-87.3-23.6170.861.30000114.6Y767 H888 C889Y767-S891 VanDerWaalsContact CE2-CA 3.44Å; H888-S891 PolarHBondContact O-OG 3.14Å; C889-S891 PolarHBondContact O-N 3.25Å
892Y43.4Very low58.9Low106 Ų10671.6 Ų71.642%0.41640%0.403SS..SBendtrans-110.683.6170.4-58.9-72.5000108.7H888 C889H888-Y892 WeakPolarHBondContact O-CD2 3.39Å; C889-Y892 CarbonylContact O-C 3.49Å; C889-Y892 PolarHBondContact O-N 3.12Å; C889-Y892 VanDerWaalsContact O-N 3.15Å
893G36.7Very low56.9Low21 Ų2172.2 Ų72.222%0.21641%0.414CS..  trans-42.7147.2171.800000111.1T895G893-T895 PolarHBondContact O-N 3.24Å; G893-T895 PolarHBondContact O-OG1 3.49Å
894Y31Very low54.6Low201 Ų20177.4 Ų77.479%0.78844%0.443SS*.SBendtrans-56.560.4-173.9-82.4-88.3000114.9
895T28.9Very low52.2Low122 Ų12281.1 Ų81.175%0.74847%0.466SS*.  trans-137.510.3-176.345.80000112.9G893G893-T895 PolarHBondContact O-N 3.24Å; G893-T895 PolarHBondContact O-OG1 3.49Å
896M27.9Very low49.5Very low184 Ų18483.8 Ų83.891%0.90648%0.48SS*.  trans-130.669.7168.8-72.1-79.9-127.100109.5
897A23.8Very low46.4Very low175 Ų17591 Ų91100%1.44652%0.52SS*.  trans-121.40155.800000107.9

Retrieved 897 of 897 residues in 386.1 ms (Link to these results)