A0A087YIX7_POEFO Loading...

Cyclin-dependent kinase 5 activator

p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-BMAL1 heterodimer in association with altered stability and subcellular distribution.

AlphaFold DB (M4AU52), UniProt , Accession A0A087YIX7, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 308 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	37.2	Very low	39.5	Very low	250 Å²	250	140.5 Å²	140.5	100%	1.232	82%	0.82	S	S	*	*				0	120.9	0	-74.8	-114.7	-93.7	0	0	107.6
2	G	39.9	Very low	39.3	Very low	70 Å²	70	150.1 Å²	150.1	72%	0.722	83%	0.832	S	S	*	*			trans	106.8	74.6	164.6	0	0	0	0	0	117.4
3	T	41	Very low	39.1	Very low	130 Å²	130	154.1 Å²	154.1	80%	0.798	84%	0.835	S	S	*	*				73.9	103.5	106.4	-17.3	0	0	0	0	115.9
4	V	40.6	Very low	38.7	Very low	115 Å²	115	149.4 Å²	149.4	70%	0.697	83%	0.828	S	S	*	*				80.2	128.1	110.3	-179.5	0	0	0	0	114
5	L	45.2	Very low	38.2	Very low	160 Å²	160	145.7 Å²	145.7	84%	0.838	82%	0.824	S	S	*	*				-171.4	114.4	96.4	-77	160.6	0	0	0	107.8
6	S	38.7	Very low	37.9	Very low	96 Å²	96	145.4 Å²	145.4	67%	0.671	82%	0.819	S	S	*	*				40	119.1	95.2	-163.4	0	0	0	0	116.2
7	L	38.2	Very low	37.6	Very low	158 Å²	158	146.6 Å²	146.6	83%	0.827	81%	0.814	S	S	*	*				159.3	113.6	118.3	-79.9	170.1	0	0	0	110.9
8	S	39.5	Very low	37.5	Very low	118 Å²	118	146.9 Å²	146.9	83%	0.825	81%	0.808	S	S	*	*			trans	-73.8	154.3	157.5	-52.2	0	0	0	0	109.9
9	P	43.3	Very low	37.4	Very low	127 Å²	127	147.6 Å²	147.6	83%	0.825	81%	0.81	S	S	*	*				-136.5	146.3	129.4	11.2	11	0	0	0	116
10	S	31.6	Very low	37.2	Very low	105 Å²	105	143.4 Å²	143.4	73%	0.734	80%	0.802	S	S	*	*			trans	-64.9	151.1	172.2	-71.3	0	0	0	0	115.7
11	Y	39.3	Very low	37.6	Very low	216 Å²	216	142.7 Å²	142.7	85%	0.847	80%	0.804	S	S	*	*			trans	42.3	126.5	138.5	-83.2	-93.5	0	0	0	120.9
12	R	37.2	Very low	37.5	Very low	256 Å²	256	134.8 Å²	134.8	97%	0.966	78%	0.779	S	S	*	*				-148.7	152.2	126.9	-75.4	-155.4	-168.7	-144.6	2.3	112.4
13	K	37.3	Very low	37.4	Very low	202 Å²	202	138 Å²	138	88%	0.878	78%	0.784	S	S	*	*			trans	-115.7	142.1	-174.1	176.5	-171.9	-175.8	179.4	0	109
14	A	33.3	Very low	37.2	Very low	89 Å²	89	138.8 Å²	138.8	74%	0.736	79%	0.789	S	S	*	*			trans	-172.2	121.7	154.4	0	0	0	0	0	107.1
15	A	31.3	Very low	36.9	Very low	93 Å²	93	136.4 Å²	136.4	77%	0.769	79%	0.788	S	S	*	*				62	137.1	81.8	0	0	0	0	0	111.6
16	L	33.2	Very low	36.3	Very low	142 Å²	142	136.1 Å²	136.1	74%	0.743	78%	0.782	S	S	*	*			cis	-179.5	172.2	14.8	-132.1	164.8	0	0	0	107.3
17	F	33	Very low	36	Very low	166 Å²	166	140.6 Å²	140.6	73%	0.728	79%	0.785	S	S	*	*			trans	80.7	118.7	171.5	-80.4	-93.4	0	0	0	118.2
18	E	36.4	Very low	36	Very low	152 Å²	152	139.7 Å²	139.7	71%	0.71	79%	0.786	S	S	*	*			cis	94.5	117.8	36.7	-171.9	167.3	161.9	0	0	112.8
19	D	34.9	Very low	35.9	Very low	159 Å²	159	138.2 Å²	138.2	85%	0.85	78%	0.782	S	S	*	*				174.6	148.6	113.6	-137.2	-21	0	0	0	114.2
20	G	32.6	Very low	35.4	Very low	63 Å²	63	138.7 Å²	138.7	65%	0.649	78%	0.782	S	S	*	*			trans	128.7	137.7	158	0	0	0	0	0	119
21	P	47	Very low	35.5	Very low	129 Å²	129	142.5 Å²	142.5	84%	0.838	79%	0.788	S	S	*	*				-135.7	171.8	-117.1	40.3	-23.5	0	0	0	119.6
22	A	33.3	Very low	35.1	Very low	85 Å²	85	139.9 Å²	139.9	70%	0.702	79%	0.789	S	S	*	*			trans	74.8	119.7	140.2	0	0	0	0	0	123.6
23	T	39.1	Very low	35	Very low	137 Å²	137	131.8 Å²	131.8	84%	0.84	77%	0.772	S	S	*	*				-177.4	104	113	37.2	0	0	0	0	109.1
24	V	37.4	Very low	35	Very low	146 Å²	146	131.6 Å²	131.6	89%	0.885	77%	0.771	S	S	*	*				56.9	125.1	97.4	-175.8	0	0	0	0	113.5
25	G	32.7	Very low	35	Very low	66 Å²	66	134.8 Å²	134.8	68%	0.68	78%	0.775	S	S	*	*			cis	-170.3	-164.8	5.1	0	0	0	0	0	107.8
26	H	33.9	Very low	35.2	Very low	154 Å²	154	135.5 Å²	135.5	71%	0.713	78%	0.781	S	S	*	*			cis	-172.1	138.9	-14.5	-125.4	24	0	0	0	105.2
27	Y	31.8	Very low	35.3	Very low	189 Å²	189	137.3 Å²	137.3	74%	0.741	78%	0.783	S	S	*	*			trans	46	138.7	154.3	-56.9	-72.9	0	0	0	121
28	T	38.8	Very low	35.3	Very low	139 Å²	139	135.2 Å²	135.2	85%	0.853	78%	0.779	S	S	*	*				-159.1	150.4	63.5	45.9	0	0	0	0	114
29	A	36.9	Very low	35.5	Very low	88 Å²	88	138 Å²	138	73%	0.727	79%	0.789	S	S	*	*			trans	-96.9	153.7	174.8	0	0	0	0	0	113
30	V	33.1	Very low	35.4	Very low	137 Å²	137	137.1 Å²	137.1	83%	0.83	78%	0.784	S	S	*	*			trans	-167.8	107.6	143.2	-112.3	0	0	0	0	107.8
31	Q	34	Very low	35.5	Very low	185 Å²	185	140.6 Å²	140.6	86%	0.864	79%	0.787	S	S	*	*				46.1	111.8	92.7	-72.1	-168.5	-16.1	0	0	115.8
32	N	29.3	Very low	34.9	Very low	160 Å²	160	142.7 Å²	142.7	86%	0.856	78%	0.783	S	S	*	*				-154.4	152.5	121.8	-148.1	-5	0	0	0	112.5
33	S	36.2	Very low	35.4	Very low	87 Å²	87	150 Å²	150	61%	0.608	79%	0.792	S	S	*	*			trans	-104.1	156	-161.2	57.1	0	0	0	0	112.1
34	K	37.9	Very low	35.5	Very low	198 Å²	198	151.7 Å²	151.7	86%	0.861	79%	0.791	S	S	*	*				-174	121.4	119.1	-104.5	168.4	-179	173.1	0	113.5
35	N	33.2	Very low	35.6	Very low	156 Å²	156	149.9 Å²	149.9	83%	0.834	78%	0.784	S	S	*	*			trans	-27.6	141.1	164.6	-66.7	-44.8	0	0	0	118.7
36	A	34.9	Very low	36.3	Very low	107 Å²	107	153.9 Å²	153.9	88%	0.884	79%	0.789	S	S	*	*				-151.1	139.5	118.8	0	0	0	0	0	111
37	K	34.1	Very low	36.7	Very low	181 Å²	181	152.9 Å²	152.9	79%	0.787	79%	0.788	S	S	*	*			trans	-81.4	149.5	-163.1	-103	177.7	161.5	179.9	0	115.3
38	D	33.1	Very low	36.8	Very low	121 Å²	121	151.5 Å²	151.5	65%	0.647	79%	0.793	S	S	*	*			trans	58.8	114.3	137.3	-54.6	-30.4	0	0	0	120.2
39	K	41.5	Very low	36.8	Very low	211 Å²	211	150.2 Å²	150.2	92%	0.917	79%	0.785	S	S	*	*				-175.2	148.7	97.2	-92.8	168.6	-170.2	179.7	0	113.5
40	N	31.9	Very low	37.4	Very low	140 Å²	140	152.8 Å²	152.8	75%	0.749	79%	0.786	S	S	*	*			trans	-69.3	143.9	-169.4	-156.9	-19.5	0	0	0	114.4
41	L	35.6	Very low	38	Very low	136 Å²	136	150.8 Å²	150.8	71%	0.712	78%	0.776	S	S	*	*				138.5	125.9	129.6	-79.6	151	0	0	0	115.7
42	K	33.5	Very low	38.5	Very low	173 Å²	173	154 Å²	154	75%	0.752	78%	0.78	S	S	*	*			trans	73.6	100.5	149.6	-69.1	179.3	177.8	179.4	0	118.8
43	R	43.8	Very low	39	Very low	238 Å²	238	154.9 Å²	154.9	90%	0.898	78%	0.776	S	S	*	*			trans	-51.5	130	151.2	-64.3	177.7	-169.4	166.7	3	110.2
44	H	42.3	Very low	39.3	Very low	174 Å²	174	160.9 Å²	160.9	81%	0.806	79%	0.786	S	S	*	*			trans	-137.8	115.1	149.1	-86.3	-84.1	0	0	0	108.2
45	S	38.6	Very low	39.7	Very low	107 Å²	107	159.9 Å²	159.9	75%	0.748	79%	0.788	S	S	*	*			trans	-82.8	123.3	170.7	-22	0	0	0	0	108.2
46	L	47.2	Very low	39.8	Very low	151 Å²	151	157.6 Å²	157.6	79%	0.791	78%	0.78	S	S	*	*			trans	-157.1	116.2	157.1	-71.9	-175.9	0	0	0	111.6
47	I	42.8	Very low	40	Very low	133 Å²	133	156.9 Å²	156.9	68%	0.682	77%	0.773	S	S	*	*			trans	52.4	97.1	131	-51.4	171.2	0	0	0	116.7	V49	I47-V49 HydrophobicContact CG2-CB 4.2Å; I47-V49 HydrophobicContact CG2-CG2 3.62Å; I47-V49 PolarHBondContact O-N 3.35Å
48	N	35.2	Very low	40	Very low	159 Å²	159	155.2 Å²	155.2	85%	0.85	78%	0.778	S	S	*	*			trans	-83.8	88.9	159.5	-105.9	12.6	0	0	0	109.8
49	V	39.1	Very low	40.1	Very low	113 Å²	113	154.8 Å²	154.8	69%	0.685	78%	0.784	S	S	*	*			trans	-117	102	160	177.3	0	0	0	0	106	I47 P51	I47-V49 HydrophobicContact CG2-CB 4.2Å; I47-V49 HydrophobicContact CG2-CG2 3.62Å; I47-V49 PolarHBondContact O-N 3.35Å; V49-P51 WeakPolarHBondContact O-CD 3.28Å
50	L	48.8	Very low	39.9	Very low	141 Å²	141	149.5 Å²	149.5	74%	0.738	78%	0.78	S	S	*	*			trans	-91.1	118	172.6	-76.7	169.2	0	0	0	109.4
51	P	46.1	Very low	40	Very low	96 Å²	96	153 Å²	153	62%	0.623	79%	0.789	S	S	*	*			trans	-89.4	113.9	174.6	33	-28	0	0	0	109.6	V49 K53	V49-P51 WeakPolarHBondContact O-CD 3.28Å; P51-K53 VanDerWaalsContact C-N 3.33Å; P51-K53 PolarHBondContact O-N 3.34Å
52	W	43.7	Very low	40	Very low	253 Å²	253	155.8 Å²	155.8	96%	0.958	80%	0.795	S	S	*	*			trans	-77.5	89.5	168.3	-72.1	-2.3	0	0	0	109.8
53	K	39.6	Very low	40.1	Very low	178 Å²	178	156.9 Å²	156.9	77%	0.774	80%	0.8	S	S	*	*			trans	-93.1	132.7	161.8	-74.3	-163.9	175.1	-166.4	0	110	P51	P51-K53 VanDerWaalsContact C-N 3.33Å; P51-K53 PolarHBondContact O-N 3.34Å
54	R	42.6	Very low	39.7	Very low	212 Å²	212	150.8 Å²	150.8	80%	0.8	79%	0.793	S	S	*	*			trans	61.2	106.5	152.2	-73.2	-173.5	-163.3	176.2	5.2	118.3	V56	R54-V56 HydrophobicContact CB-CG2 3.99Å; R54-V56 HydrophobicContact CG-CG2 4.15Å
55	I	45.8	Very low	39.4	Very low	177 Å²	177	148.2 Å²	148.2	91%	0.908	80%	0.795	S	S	*	*			trans	-95.3	111.7	139.7	-61.5	174.3	0	0	0	106.2
56	V	36.1	Very low	39.4	Very low	109 Å²	109	152.7 Å²	152.7	66%	0.661	80%	0.801	S	S	*	*			trans	-103.7	119.5	167.6	-162.9	0	0	0	0	105.7	R54	R54-V56 HydrophobicContact CB-CG2 3.99Å; R54-V56 HydrophobicContact CG-CG2 4.15Å
57	A	39.6	Very low	39.1	Very low	91 Å²	91	155.5 Å²	155.5	75%	0.752	81%	0.807	S	S	*	*			trans	-68.3	135.7	174.4	0	0	0	0	0	110.1	S59	A57-S59 PolarHBondContact O-N 3.44Å
58	V	33.4	Very low	38.8	Very low	146 Å²	146	155.7 Å²	155.7	89%	0.885	81%	0.814	S	S	*	*			trans	-71.2	109.6	-179.3	-178.8	0	0	0	0	109.1
59	S	35.3	Very low	39.4	Very low	112 Å²	112	156.1 Å²	156.1	78%	0.783	81%	0.811	S	S	*	*	P	Polyproline II helix	trans	-90.8	121.8	167.6	60	0	0	0	0	110	A57	A57-S59 PolarHBondContact O-N 3.44Å
60	A	36.5	Very low	39.4	Very low	100 Å²	100	157.2 Å²	157.2	83%	0.826	82%	0.82	S	S	*	*	P	Polyproline II helix	trans	-58.6	144.9	174.7	0	0	0	0	0	112.5	K62	A60-K62 PolarHBondContact O-N 3.22Å
61	K	34	Very low	39.2	Very low	213 Å²	213	156 Å²	156	93%	0.926	81%	0.814	S	S	*	*	P	Polyproline II helix	trans	-54.2	117.7	-175.7	-167.4	-178.4	-172.8	-179.5	0	114
62	K	36.6	Very low	39.5	Very low	196 Å²	196	155.2 Å²	155.2	85%	0.852	82%	0.816	S	S	*	*			trans	-158.7	111.2	147	-150.7	171.7	-178.8	179.9	0	114	A60	A60-K62 PolarHBondContact O-N 3.22Å
63	K	35	Very low	39.9	Very low	196 Å²	196	146.9 Å²	146.9	85%	0.852	79%	0.794	S	S	*	*			trans	46.4	107.1	141.3	-144.5	173.2	-175	-179.5	0	120.3
64	S	35.3	Very low	40.4	Very low	109 Å²	109	146.9 Å²	146.9	76%	0.762	79%	0.79	S	S	*	*			trans	37	117.9	143.2	-167.6	0	0	0	0	120.5
65	S	36	Very low	40.9	Very low	121 Å²	121	144.5 Å²	144.5	85%	0.846	79%	0.788	S	S	*	*				-178.5	152.3	124	-78.8	0	0	0	0	114.2
66	K	39.2	Very low	41.3	Very low	200 Å²	200	141.7 Å²	141.7	87%	0.87	78%	0.775	S	S	*	*			trans	-22.4	139.3	-177.3	-80.4	166	173.3	171.9	0	121.8
67	K	41.5	Very low	42.6	Very low	211 Å²	211	140.5 Å²	140.5	92%	0.917	76%	0.764	S	S	*	*			trans	-50.6	129.3	163.4	-175.9	179.6	-176.2	-179.1	0	113.4
68	V	36	Very low	43.7	Very low	136 Å²	136	140.5 Å²	140.5	82%	0.824	76%	0.755	S	S	*	*			trans	-134.2	133.3	169.6	-179.5	0	0	0	0	109.7
69	Q	46.8	Very low	45.1	Very low	169 Å²	169	136 Å²	136	79%	0.79	73%	0.73	S	S	*	*	P	Polyproline II helix	trans	-70.1	149.1	175.4	-73	174.9	-9	0	0	111.3	N71	Q69-N71 PolarHBondContact O-N 3.38Å
70	P	40.5	Very low	46.6	Very low	135 Å²	135	136.1 Å²	136.1	88%	0.877	72%	0.718	S	S	*	*	P	Polyproline II helix	trans	-78.7	121.4	178.1	31.2	-29.3	0	0	0	110.7
71	N	43.9	Very low	47.9	Very low	115 Å²	115	136.2 Å²	136.2	62%	0.615	70%	0.704	S	S	*	*	P	Polyproline II helix	trans	-79.2	131.5	176.6	-110.9	-8.5	0	0	0	111.1	Q69 T73 Y74	Q69-N71 PolarHBondContact O-N 3.38Å; N71-T73 PolarHBondContact O-N 3.17Å; N71-Y74 HydrophobicContact CB-CD2 4.39Å; N71-Y74 PolarHBondContact O-N 3.04Å
72	A	52.2	Low	49.2	Very low	80 Å²	80	127.9 Å²	127.9	66%	0.661	67%	0.67	S	S	*	*	T	Hydrogen-bonded Turn	trans	-60.7	-8.7	175.4	0	0	0	0	0	114.6
73	T	52.8	Low	50.3	Low	79 Å²	79	122.7 Å²	122.7	49%	0.485	65%	0.651	S	S	.	*	H	α-helix	trans	-73.8	-25.4	-179.3	-36.9	0	0	0	0	113.3	N71 N77	N71-T73 PolarHBondContact O-N 3.17Å; T73-N77 PolarHBondContact O-N 3.18Å; T73-N77 PolarHBondContact O-ND2 3.47Å
74	Y	50.2	Low	51.5	Low	178 Å²	178	116 Å²	116	70%	0.698	62%	0.623	S	S	*	*	H	α-helix	trans	-72.8	-37.5	-178.4	-79.7	-81	0	0	0	112.8	N71 N76 N77 V78	N71-Y74 HydrophobicContact CB-CD2 4.39Å; N71-Y74 PolarHBondContact O-N 3.04Å; Y74-N76 PolarHBondContact O-N 2.93Å; Y74-N77 PolarHBondContact O-N 3.44Å; Y74-V78 WeakPolarHBondContact O-CG2 3.37Å; Y74-V78 PolarHBondContact O-N 3.12Å
75	Q	52	Low	52.6	Low	161 Å²	161	115.2 Å²	115.2	75%	0.752	61%	0.61	S	S	*	*	H	α-helix	trans	-64.8	-40.9	177.1	-72.9	-137.2	-44.9	0	0	112.1	N77 V78 S79	Q75-N77 VanDerWaalsContact C-N 3.29Å; Q75-N77 PolarHBondContact O-N 3.34Å; Q75-V78 PolarHBondContact O-N 3.42Å; Q75-S79 PolarHBondContact O-N 3.07Å; Q75-S79 VanDerWaalsContact O-N 3.11Å; Q75-S79 PolarHBondContact O-OG 3.49Å
76	N	55.5	Low	53.7	Low	119 Å²	119	113 Å²	113	64%	0.636	59%	0.588	S	S	*	*	H	α-helix	trans	-62.1	-35.6	176.2	-83.4	-60.2	0	0	0	113	Y74 H80	Y74-N76 PolarHBondContact O-N 2.93Å; N76-H80 VanDerWaalsContact O-CB 3.3Å; N76-H80 WeakPolarHBondContact O-CB 3.44Å; N76-H80 PolarHBondContact O-N 3.09Å
77	N	61.9	Low	54.4	Low	83 Å²	83	110 Å²	110	44%	0.444	58%	0.576	S	S	.	*	H	α-helix	trans	-68.3	-40.6	176.9	-82.4	-70.6	0	0	0	112	T73 Y74 Q75 H80 L81	T73-N77 PolarHBondContact O-N 3.18Å; T73-N77 PolarHBondContact O-ND2 3.47Å; Y74-N77 PolarHBondContact O-N 3.44Å; Q75-N77 VanDerWaalsContact C-N 3.29Å; Q75-N77 PolarHBondContact O-N 3.34Å; N77-H80 PolarHBondContact O-N 2.68Å; N77-L81 WeakPolarHBondContact O-CB 3.42Å; N77-L81 VanDerWaalsContact O-CD1 3.32Å; N77-L81 WeakPolarHBondContact O-CD1 3.47Å; N77-L81 WeakPolarHBondContact O-CG 3.4Å; N77-L81 PolarHBondContact O-N 3.36Å
78	V	63.1	Low	54.8	Low	91 Å²	91	107.1 Å²	107.1	55%	0.552	56%	0.563	S	S	*	*	H	α-helix	trans	-64.5	-46.8	178.3	176.9	0	0	0	0	110.9	Y74 Q75 H80 L81 N82	Y74-V78 WeakPolarHBondContact O-CG2 3.37Å; Y74-V78 PolarHBondContact O-N 3.12Å; Q75-V78 PolarHBondContact O-N 3.42Å; V78-H80 VanDerWaalsContact C-N 3.29Å; V78-H80 PolarHBondContact O-N 3.09Å; V78-L81 PolarHBondContact O-N 3Å; V78-N82 WeakPolarHBondContact O-CB 3.4Å; V78-N82 PolarHBondContact O-N 3.48Å
79	S	63.2	Low	55.2	Low	52 Å²	52	103.9 Å²	103.9	36%	0.364	55%	0.546	S	S	.	.	H	α-helix	trans	-62.7	-36.8	176.9	-52.8	0	0	0	0	112.2	Q75 N82 N83	Q75-S79 PolarHBondContact O-N 3.07Å; Q75-S79 VanDerWaalsContact O-N 3.11Å; Q75-S79 PolarHBondContact O-OG 3.49Å; S79-N82 PolarHBondContact O-N 3.31Å; S79-N83 PolarHBondContact O-N 3.4Å; S79-N83 VanDerWaalsContact O-N 3.09Å; S79-N83 PolarHBondContact O-ND2 3.36Å
80	H	65.7	Low	55.3	Low	115 Å²	115	105.1 Å²	105.1	53%	0.532	55%	0.552	S	S	.	*	H	α-helix	trans	-67.4	-43.5	174.8	-175.3	-87.7	0	0	0	112.3	N76 N77 V78 N82 N83 E84	N76-H80 VanDerWaalsContact O-CB 3.3Å; N76-H80 WeakPolarHBondContact O-CB 3.44Å; N76-H80 PolarHBondContact O-N 3.09Å; N77-H80 PolarHBondContact O-N 2.68Å; V78-H80 VanDerWaalsContact C-N 3.29Å; V78-H80 PolarHBondContact O-N 3.09Å; H80-N82 VanDerWaalsContact C-N 3.34Å; H80-N82 PolarHBondContact O-N 2.92Å; H80-N83 PolarHBondContact O-N 3.06Å; H80-E84 WeakPolarHBondContact O-CG 3.38Å; H80-E84 PolarHBondContact O-N 3.09Å
81	L	64.4	Low	55.7	Low	101 Å²	101	100 Å²	100	53%	0.529	52%	0.519	S	S	.	.	H	α-helix	trans	-63.9	-37.6	174.9	-82.5	150.2	0	0	0	111.8	N77 V78 E84 N85	N77-L81 WeakPolarHBondContact O-CB 3.42Å; N77-L81 VanDerWaalsContact O-CD1 3.32Å; N77-L81 WeakPolarHBondContact O-CD1 3.47Å; N77-L81 WeakPolarHBondContact O-CG 3.4Å; N77-L81 PolarHBondContact O-N 3.36Å; V78-L81 PolarHBondContact O-N 3Å; L81-E84 PolarHBondContact O-N 2.95Å; L81-N85 PolarHBondContact O-N 3.38Å; L81-N85 PolarHBondContact O-ND2 2.87Å
82	N	60.8	Low	55.9	Low	38 Å²	38	96.2 Å²	96.2	20%	0.203	50%	0.502	C	S	.	.	H	α-helix	trans	-64.2	-43.9	175.9	-154.7	11	0	0	0	111	V78 S79 H80 E84 N85 L86	V78-N82 WeakPolarHBondContact O-CB 3.4Å; V78-N82 PolarHBondContact O-N 3.48Å; S79-N82 PolarHBondContact O-N 3.31Å; H80-N82 VanDerWaalsContact C-N 3.34Å; H80-N82 PolarHBondContact O-N 2.92Å; N82-E84 VanDerWaalsContact C-N 3.34Å; N82-E84 PolarHBondContact O-N 3.26Å; N82-N85 PolarHBondContact O-N 3.4Å; N82-L86 PolarHBondContact O-N 3.27Å
83	N	61.6	Low	55.8	Low	87 Å²	87	94.8 Å²	94.8	47%	0.465	49%	0.489	S	S	.	.	H	α-helix	trans	-62.8	-35.2	173.2	-82.4	-34.9	0	0	0	113.6	S79 H80 L86 K87	S79-N83 PolarHBondContact O-N 3.4Å; S79-N83 VanDerWaalsContact O-N 3.09Å; S79-N83 PolarHBondContact O-ND2 3.36Å; H80-N83 PolarHBondContact O-N 3.06Å; N83-L86 WeakPolarHBondContact O-CB 3.33Å; N83-L86 PolarHBondContact O-N 2.93Å; N83-K87 PolarHBondContact O-N 2.78Å
84	E	58.5	Low	55.5	Low	57 Å²	57	94.2 Å²	94.2	27%	0.266	48%	0.483	S	S	.	.	H	α-helix	trans	-72.9	-34.6	176.1	-76.2	-68.4	123	0	0	112.4	H80 L81 N82 L86 K87 K88	H80-E84 WeakPolarHBondContact O-CG 3.38Å; H80-E84 PolarHBondContact O-N 3.09Å; L81-E84 PolarHBondContact O-N 2.95Å; N82-E84 VanDerWaalsContact C-N 3.34Å; N82-E84 PolarHBondContact O-N 3.26Å; E84-L86 VanDerWaalsContact C-N 3.33Å; E84-K87 PolarHBondContact O-N 2.79Å; E84-K87 IonicContact OE1-NZ 3.18Å; E84-K87 PolarHBondContact OE1-NZ 2.93Å; E84-K88 WeakPolarHBondContact O-CG 3.25Å; E84-K88 PolarHBondContact O-N 2.8Å
85	N	59.3	Low	55.3	Low	91 Å²	91	90.9 Å²	90.9	49%	0.487	48%	0.477	S	S	.	.	H	α-helix	trans	-66	-36.5	171.1	-76.2	-65.1	0	0	0	111.6	L81 N82 K87 K88 S89	L81-N85 PolarHBondContact O-N 3.38Å; L81-N85 PolarHBondContact O-ND2 2.87Å; N82-N85 PolarHBondContact O-N 3.4Å; N85-K87 PolarHBondContact O-N 3.2Å; N85-K88 PolarHBondContact O-N 2.9Å; N85-S89 PolarHBondContact O-N 3.43Å
86	L	58	Low	54.8	Low	74 Å²	74	87.5 Å²	87.5	39%	0.387	47%	0.471	S	S	.	.	H	α-helix	trans	-56.9	-37.3	172.4	-168.7	75.2	0	0	0	112.3	N82 N83 E84	N82-L86 PolarHBondContact O-N 3.27Å; N83-L86 WeakPolarHBondContact O-CB 3.33Å; N83-L86 PolarHBondContact O-N 2.93Å; E84-L86 VanDerWaalsContact C-N 3.33Å
87	K	55.1	Low	53.8	Low	139 Å²	139	85.3 Å²	85.3	60%	0.604	47%	0.466	S	S	*	.	H	α-helix	trans	-74.6	-27.6	176.1	-66.1	177.4	-170.3	164.2	0	113.3	N83 E84 N85	N83-K87 PolarHBondContact O-N 2.78Å; E84-K87 PolarHBondContact O-N 2.79Å; E84-K87 IonicContact OE1-NZ 3.18Å; E84-K87 PolarHBondContact OE1-NZ 2.93Å; N85-K87 PolarHBondContact O-N 3.2Å
88	K	48.7	Very low	52.7	Low	150 Å²	150	87.7 Å²	87.7	65%	0.652	47%	0.472	S	S	*	.	H	α-helix	trans	-95.6	-21.8	-174.1	-72.8	178.5	-177.2	176	0	114.4	E84 N85 Q90	E84-K88 WeakPolarHBondContact O-CG 3.25Å; E84-K88 PolarHBondContact O-N 2.8Å; N85-K88 PolarHBondContact O-N 2.9Å; K88-Q90 PolarHBondContact O-N 2.99Å; K88-Q90 VanDerWaalsContact O-N 3.09Å
89	S	46.3	Very low	51.5	Low	67 Å²	67	89.2 Å²	89.2	47%	0.469	48%	0.482	S	S	.	.	S	Bend	trans	-61.9	112.3	171.5	-82.9	0	0	0	0	109.3	N85 S91	N85-S89 PolarHBondContact O-N 3.43Å; S89-S91 PolarHBondContact O-N 3.38Å
90	Q	47.6	Very low	50.4	Low	196 Å²	196	95.4 Å²	95.4	92%	0.916	51%	0.505	S	S	*	.			trans	-71.2	38.8	177.1	-61.3	-172	5.9	0	0	112.5	K88	K88-Q90 PolarHBondContact O-N 2.99Å; K88-Q90 VanDerWaalsContact O-N 3.09Å
91	S	49.8	Very low	48.7	Very low	27 Å²	27	97.9 Å²	97.9	19%	0.189	52%	0.522	C	S	.	.			trans	-81.9	138.3	168.4	-177.2	0	0	0	0	108.1	S89 A93 N270	S89-S91 PolarHBondContact O-N 3.38Å; S91-A93 PolarHBondContact O-N 3.14Å; S91-N270 PolarHBondContact OG-OD1 3.34Å
92	C	48.1	Very low	47.2	Very low	36 Å²	36	102.1 Å²	102.1	24%	0.243	54%	0.539	C	S	.	.	T	Hydrogen-bonded Turn	trans	-58.5	5.8	173	42.8	0	0	0	0	114.6	N94	C92-N94 PolarHBondContact O-N 2.84Å
93	A	49.7	Very low	45.8	Very low	49 Å²	49	105.6 Å²	105.6	41%	0.405	57%	0.566	S	S	.	*	T	Hydrogen-bonded Turn	trans	-68.2	-10.7	173	0	0	0	0	0	115	S91 L95 A193	S91-A93 PolarHBondContact O-N 3.14Å; A93-L95 PolarHBondContact O-N 2.96Å; A93-A193 HydrophobicContact CB-CB 3.84Å
94	N	45.5	Very low	44.3	Very low	67 Å²	67	106.7 Å²	106.7	36%	0.358	58%	0.581	S	S	.	*			trans	-75.9	66.7	172.7	-91.5	-54	0	0	0	111.8	C92 S96	C92-N94 PolarHBondContact O-N 2.84Å; N94-S96 VanDerWaalsContact C-N 3.31Å
95	L	47.3	Very low	43.2	Very low	108 Å²	108	109.7 Å²	109.7	57%	0.565	61%	0.606	S	S	*	*			trans	-82	-10.1	166.1	-107.1	79.6	0	0	0	112.7	A93	A93-L95 PolarHBondContact O-N 2.96Å
96	S	40.8	Very low	41.8	Very low	90 Å²	90	109.9 Å²	109.9	63%	0.629	62%	0.62	S	S	*	*	S	Bend	trans	-94.1	-7.6	-174.8	48	0	0	0	0	115.1	N94 F98	N94-S96 VanDerWaalsContact C-N 3.31Å; S96-F98 PolarHBondContact O-N 2.95Å
97	S	34.3	Very low	40.4	Very low	74 Å²	74	114.7 Å²	114.7	52%	0.517	65%	0.645	S	S	.	*	T	Hydrogen-bonded Turn	trans	-91.7	15.7	-175.9	49	0	0	0	0	115.3
98	F	40.2	Very low	39.4	Very low	132 Å²	132	113.5 Å²	113.5	58%	0.579	65%	0.654	S	S	*	*	T	Hydrogen-bonded Turn	trans	-118.3	12.8	177.8	-74.9	-59.4	0	0	0	115.9	S96 R135	S96-F98 PolarHBondContact O-N 2.95Å; F98-R135 VanDerWaalsContact CZ-CZ 3.44Å
99	T	37.5	Very low	38.5	Very low	124 Å²	124	116.3 Å²	116.3	76%	0.761	67%	0.666	S	S	*	*	S	Bend	trans	-107.2	17.6	-178.1	48.5	0	0	0	0	115.3
100	Q	38.8	Very low	37.7	Very low	181 Å²	181	119.2 Å²	119.2	85%	0.846	69%	0.687	S	S	*	*			trans	-147.7	83.6	177.6	-148	169.7	6.2	0	0	112.8
101	D	30.4	Very low	36.9	Very low	167 Å²	167	114.3 Å²	114.3	89%	0.893	67%	0.674	S	S	*	*			trans	-144.2	76.2	149.4	-93.3	-29.5	0	0	0	108
102	Q	33.3	Very low	36	Very low	191 Å²	191	119.4 Å²	119.4	89%	0.893	70%	0.699	S	S	*	*			trans	-104.8	96.1	148.8	-90.5	-171.2	11.3	0	0	107	S104	Q102-S104 PolarHBondContact O-N 3.15Å
103	S	31.2	Very low	35.1	Very low	110 Å²	110	124.1 Å²	124.1	77%	0.769	72%	0.722	S	S	*	*			trans	-61.1	107.3	166.3	52.3	0	0	0	0	109.9	P105	S103-P105 WeakPolarHBondContact O-CD 3.47Å
104	S	30.7	Very low	34.2	Very low	110 Å²	110	127 Å²	127	77%	0.769	73%	0.734	S	S	*	*	P	Polyproline II helix	trans	-76.5	117.2	154	49.7	0	0	0	0	108.4	Q102 A106	Q102-S104 PolarHBondContact O-N 3.15Å; S104-A106 PolarHBondContact O-N 3.33Å
105	P	34.3	Very low	33.4	Very low	121 Å²	121	129.9 Å²	129.9	79%	0.786	76%	0.755	S	S	*	*	P	Polyproline II helix	trans	-78.5	117.5	173.9	24.4	-19.6	0	0	0	109.7	S103	S103-P105 WeakPolarHBondContact O-CD 3.47Å
106	A	30.1	Very low	32.6	Very low	95 Å²	95	130.3 Å²	130.3	79%	0.785	77%	0.767	S	S	*	*	P	Polyproline II helix	trans	-62.7	138.2	168.7	0	0	0	0	0	110.5	S104 S108	S104-A106 PolarHBondContact O-N 3.33Å; A106-S108 PolarHBondContact O-N 3.29Å
107	L	29.6	Very low	32.2	Very low	174 Å²	174	131.3 Å²	131.3	91%	0.911	77%	0.774	S	S	*	*	P	Polyproline II helix	trans	-62.9	121.6	171.8	-75.1	92.1	0	0	0	110.4
108	S	32.5	Very low	32.1	Very low	115 Å²	115	133 Å²	133	80%	0.804	78%	0.781	S	S	*	*			trans	-121.6	121.1	155.5	59.1	0	0	0	0	109.2	A106	A106-S108 PolarHBondContact O-N 3.29Å
109	K	30.8	Very low	31.8	Very low	208 Å²	208	136.1 Å²	136.1	90%	0.904	79%	0.794	S	S	*	*			trans	-76.3	124.9	172.3	-71.9	174.2	176.4	176.2	0	108.4
110	S	29.8	Very low	31.7	Very low	128 Å²	128	140.4 Å²	140.4	90%	0.895	80%	0.802	S	S	*	*			trans	-153.2	143.4	146.8	-162.6	0	0	0	0	110.2
111	S	30.6	Very low	31.4	Very low	94 Å²	94	136.1 Å²	136.1	66%	0.657	80%	0.798	S	S	*	*			trans	-97.6	156.4	-161	-152.9	0	0	0	0	112.5
112	N	30.3	Very low	31.8	Very low	133 Å²	133	134.3 Å²	134.3	71%	0.711	80%	0.795	S	S	*	*			trans	83.4	107.4	152.8	-61.8	-3.9	0	0	0	119.5
113	N	30.1	Very low	31.9	Very low	136 Å²	136	133.2 Å²	133.2	73%	0.727	80%	0.795	S	S	*	*				139.6	125	99.9	-99	5.1	0	0	0	115.7
114	T	29.9	Very low	32.4	Very low	108 Å²	108	134 Å²	134	66%	0.663	80%	0.795	S	S	*	*			trans	75.8	99.1	137.4	55.1	0	0	0	0	122.5
115	T	28.6	Very low	32.5	Very low	129 Å²	129	135.9 Å²	135.9	79%	0.791	80%	0.796	S	S	*	*				60.8	139.9	118	59.3	0	0	0	0	124.3
116	S	31.6	Very low	33	Very low	116 Å²	116	135 Å²	135	81%	0.811	79%	0.793	S	S	*	*			trans	99.1	100.4	159.8	75.9	0	0	0	0	115
117	S	31.8	Very low	33.2	Very low	111 Å²	111	138.1 Å²	138.1	78%	0.776	80%	0.797	S	S	*	*				72.1	129.4	71.2	-162.5	0	0	0	0	114.2
118	V	32	Very low	33.7	Very low	111 Å²	111	136.9 Å²	136.9	67%	0.673	80%	0.796	S	S	*	*			trans	117.2	103.5	150.2	-172.9	0	0	0	0	117.5
119	K	33.6	Very low	34	Very low	197 Å²	197	134.9 Å²	134.9	86%	0.857	79%	0.786	S	S	*	*			trans	80.1	119.6	136.4	-68	171.2	-169.2	177.4	0	122.8
120	K	35.2	Very low	34.7	Very low	214 Å²	214	131.4 Å²	131.4	93%	0.93	79%	0.785	S	S	*	*			trans	-54.1	140.5	151.7	-95.5	175.1	168.5	175.3	0	112.8
121	A	32.3	Very low	35.2	Very low	91 Å²	91	128.2 Å²	128.2	75%	0.752	77%	0.773	S	S	*	*			trans	-151.7	145.4	138.1	0	0	0	0	0	109.7
122	P	40.3	Very low	35.9	Very low	128 Å²	128	129.3 Å²	129.3	83%	0.831	78%	0.775	S	S	*	*			trans	-91	132	-173	34	-28.6	0	0	0	111.3
123	L	35	Very low	36.5	Very low	169 Å²	169	128.9 Å²	128.9	89%	0.885	78%	0.78	S	S	*	*			trans	-122.5	109.1	167.9	-76.3	165	0	0	0	108.9	N125	L123-N125 PolarHBondContact O-N 3.38Å
124	T	41.1	Very low	37.1	Very low	125 Å²	125	131.9 Å²	131.9	77%	0.767	79%	0.786	S	S	*	*			trans	-48.9	125.4	152.2	48.3	0	0	0	0	108.9
125	N	32.8	Very low	38	Very low	151 Å²	151	134.7 Å²	134.7	81%	0.807	79%	0.785	S	S	*	*			trans	-165.8	132.1	139.8	-98.1	-1	0	0	0	111.1	L123 N127	L123-N125 PolarHBondContact O-N 3.38Å; N125-N127 PolarHBondContact O-N 3.38Å
126	S	45.3	Very low	39.1	Very low	102 Å²	102	134.1 Å²	134.1	71%	0.713	78%	0.781	S	S	*	*			trans	-35.9	121.3	166.4	47.3	0	0	0	0	113.9
127	N	34.3	Very low	39.9	Very low	161 Å²	161	135.3 Å²	135.3	86%	0.861	78%	0.777	S	S	*	*			trans	-152	83.9	152	-92.1	-22.7	0	0	0	107.5	N125 A129	N125-N127 PolarHBondContact O-N 3.38Å; N127-A129 PolarHBondContact O-N 3.34Å
128	V	40.4	Very low	41.3	Very low	148 Å²	148	132 Å²	132	90%	0.897	75%	0.751	S	S	*	*			trans	-72.9	89.7	162	-178.9	0	0	0	0	105.8
129	A	38.2	Very low	43.5	Very low	73 Å²	73	134.4 Å²	134.4	60%	0.603	76%	0.755	S	S	*	*			trans	-57.4	139.8	162.7	0	0	0	0	0	108.2	N127 G131	N127-A129 PolarHBondContact O-N 3.34Å; A129-G131 PolarHBondContact O-N 2.74Å
130	P	45.7	Very low	45.9	Very low	134 Å²	134	125.7 Å²	125.7	87%	0.87	72%	0.72	S	S	*	*			trans	-69.6	84.3	170	27.8	-28.8	0	0	0	107.5	T132	P130-T132 PolarHBondContact O-N 3.38Å
131	G	41	Very low	48.7	Very low	62 Å²	62	118.4 Å²	118.4	64%	0.639	70%	0.696	S	S	*	*			trans	-67.5	104.7	-179.5	0	0	0	0	0	109.3	A129	A129-G131 PolarHBondContact O-N 2.74Å
132	T	44	Very low	51.8	Low	117 Å²	117	115.6 Å²	115.6	72%	0.718	67%	0.67	S	S	*	*			trans	31.6	122.8	150.7	54.4	0	0	0	0	117	P130 K134	P130-T132 PolarHBondContact O-N 3.38Å; T132-K134 PolarHBondContact O-N 2.86Å
133	P	42.9	Very low	54.5	Low	123 Å²	123	113 Å²	113	80%	0.799	66%	0.655	S	S	*	*			trans	-54.2	118.7	176.1	22	-30.8	0	0	0	109	R135	P133-R135 PolarHBondContact O-N 3.49Å
134	K	43.2	Very low	57.4	Low	199 Å²	199	108.6 Å²	108.6	87%	0.865	63%	0.63	S	S	*	*			trans	-52.5	107.2	174.5	-73.6	179.2	179.9	175.8	0	106.7	T132 V136	T132-K134 PolarHBondContact O-N 2.86Å; K134-V136 PolarHBondContact O-N 3.36Å
135	R	48.4	Very low	60.2	Low	167 Å²	167	102.6 Å²	102.6	63%	0.63	59%	0.593	S	S	*	*			trans	-64.8	108	178.4	-71.9	-177.8	-175	156.8	-1.4	107.6	F98 P133 I137	F98-R135 VanDerWaalsContact CZ-CZ 3.44Å; P133-R135 PolarHBondContact O-N 3.49Å; R135-I137 PolarHBondContact O-N 3.1Å
136	V	51.5	Low	63.3	Low	118 Å²	118	95.5 Å²	95.5	72%	0.715	56%	0.555	S	S	*	*			trans	-71.1	100.9	169.1	-173.2	0	0	0	0	105.8	K134 V138	K134-V136 PolarHBondContact O-N 3.36Å; V136-V138 VanDerWaalsContact C-N 3.32Å; V136-V138 HydrophobicContact CB-CG2 4.39Å; V136-V138 HydrophobicContact CG1-CG2 3.8Å; V136-V138 PolarHBondContact O-N 3.47Å
137	I	49.9	Very low	65.8	Low	140 Å²	140	97.9 Å²	97.9	72%	0.718	55%	0.548	S	S	*	.			trans	-74.5	93.6	172.2	-60.7	173.4	0	0	0	106	R135 Q139	R135-I137 PolarHBondContact O-N 3.1Å; I137-Q139 PolarHBondContact O-N 3.13Å
138	V	60	Low	68.8	Low	41 Å²	41	90.3 Å²	90.3	25%	0.248	51%	0.508	C	S	.	.			trans	-85.3	97.2	175.2	-145.1	0	0	0	0	108.2	V136 F280	V136-V138 VanDerWaalsContact C-N 3.32Å; V136-V138 HydrophobicContact CB-CG2 4.39Å; V136-V138 HydrophobicContact CG1-CG2 3.8Å; V136-V138 PolarHBondContact O-N 3.47Å; V138-F280 HydrophobicContact CB-CD1 4.09Å; V138-F280 HydrophobicContact CB-CE1 3.6Å; V138-F280 HydrophobicContact CB-CZ 4.15Å; V138-F280 HydrophobicContact CG1-CD1 3.75Å; V138-F280 HydrophobicContact CG1-CE1 3.15Å; V138-F280 HydrophobicContact CG1-CZ 4.01Å
139	Q	77.7	Confident	71.6	Confident	162 Å²	162	83.3 Å²	83.3	76%	0.757	47%	0.465	S	S	*	.			trans	-91.4	129.1	177.4	-166.7	-179.7	-19.4	0	0	109.8	I137 K284	I137-Q139 PolarHBondContact O-N 3.13Å; Q139-K284 PolarHBondContact O-NZ 3.41Å
140	A	84.7	Confident	74.4	Confident	14 Å²	14	79.8 Å²	79.8	12%	0.116	44%	0.437	C	S	.	.			trans	-146.7	145.2	163	0	0	0	0	0	108.2	E144 L145 F280 K284	A140-E144 WeakPolarHBondContact CA-OE2 3.49Å; A140-L145 HydrophobicContact CB-CD1 4.3Å; A140-L145 HydrophobicContact CB-CD2 3.75Å; A140-L145 HydrophobicContact CB-CG 3.88Å; A140-F280 HydrophobicContact CB-CE2 4.31Å; A140-F280 HydrophobicContact CB-CZ 3.68Å; A140-K284 HydrophobicContact CB-CD 3.99Å; A140-K284 HydrophobicContact CB-CG 4.45Å
141	S	95.1	Very high	76.9	Confident	62 Å²	62	73.8 Å²	73.8	43%	0.434	40%	0.397	S	S	.	.			trans	-76.9	153.9	174.6	72.5	0	0	0	0	110.8	S143 E144 L145	S141-S143 PolarHBondContact O-N 3.36Å; S141-E144 PolarHBondContact N-OE2 3.26Å; S141-E144 WeakPolarHBondContact O-CB 3.48Å; S141-E144 PolarHBondContact O-N 3.24Å; S141-E144 VanDerWaalsContact O-N 3.16Å; S141-E144 VanDerWaalsContact OG-CB 3.25Å; S141-E144 WeakPolarHBondContact OG-CB 3.29Å; S141-E144 PolarHBondContact OG-N 3.31Å; S141-E144 VanDerWaalsContact OG-N 3.08Å; S141-L145 PolarHBondContact O-N 3.31Å
142	T	97	Very high	79.6	Confident	32 Å²	32	71.1 Å²	71.1	20%	0.196	37%	0.368	C	S	.	.	H	α-helix	trans	-56	-39.1	173.6	-47.8	0	0	0	0	111.8	L145 L146 I190 P192 V195	T142-L145 PolarHBondContact O-N 3.03Å; T142-L146 HydrophobicContact CG2-CD1 4.08Å; T142-L146 HydrophobicContact CG2-CG 4.47Å; T142-L146 WeakPolarHBondContact O-CB 3.42Å; T142-L146 VanDerWaalsContact O-CG 3.25Å; T142-L146 WeakPolarHBondContact O-CG 3.43Å; T142-L146 PolarHBondContact O-N 3.42Å; T142-I190 HydrophobicContact CG2-CG2 3.71Å; T142-I190 WeakPolarHBondContact CG2-O 3.43Å; T142-P192 VanDerWaalsContact OG1-CD 3.31Å; T142-P192 WeakPolarHBondContact OG1-CD 3.38Å; T142-P192 WeakPolarHBondContact OG1-CG 3.43Å; T142-V195 HydrophobicContact CG2-CG2 4.16Å
143	S	96.9	Very high	82.2	Confident	74 Å²	74	65.5 Å²	65.5	52%	0.517	33%	0.333	S	S	.	.	H	α-helix	trans	-65.8	-39.2	179.2	-59.3	0	0	0	0	112.4	S141 R147	S141-S143 PolarHBondContact O-N 3.36Å; S143-R147 WeakPolarHBondContact O-CB 3.31Å; S143-R147 PolarHBondContact O-N 3.01Å
144	E	96.3	Very high	84.8	Confident	75 Å²	75	60.9 Å²	60.9	35%	0.35	30%	0.304	S	S	.	.	H	α-helix	trans	-63.6	-45.9	174.7	-178.8	-171.8	166.2	0	0	111.4	A140 S141 L146 R147 C148 K284	A140-E144 WeakPolarHBondContact CA-OE2 3.49Å; S141-E144 PolarHBondContact N-OE2 3.26Å; S141-E144 WeakPolarHBondContact O-CB 3.48Å; S141-E144 PolarHBondContact O-N 3.24Å; S141-E144 VanDerWaalsContact O-N 3.16Å; S141-E144 VanDerWaalsContact OG-CB 3.25Å; S141-E144 WeakPolarHBondContact OG-CB 3.29Å; S141-E144 PolarHBondContact OG-N 3.31Å; S141-E144 VanDerWaalsContact OG-N 3.08Å; E144-L146 PolarHBondContact O-N 3.14Å; E144-R147 WeakPolarHBondContact O-CB 3.39Å; E144-R147 PolarHBondContact O-N 2.96Å; E144-C148 PolarHBondContact O-N 2.81Å; E144-C148 PolarHBondContact O-SG 3.08Å; E144-K284 IonicContact OE1-NZ 3.24Å
145	L	98.1	Very high	87.3	Confident	0 Å²	0	54.6 Å²	54.6	0%	0	28%	0.275	C	S	.	.	H	α-helix	trans	-66.6	-38.2	178.6	-64.9	179	0	0	0	112.7	A140 S141 T142 R147 C148 L149 P192 V195 V196 F280 L283 K284	A140-L145 HydrophobicContact CB-CD1 4.3Å; A140-L145 HydrophobicContact CB-CD2 3.75Å; A140-L145 HydrophobicContact CB-CG 3.88Å; S141-L145 PolarHBondContact O-N 3.31Å; T142-L145 PolarHBondContact O-N 3.03Å; L145-R147 VanDerWaalsContact C-N 3.31Å; L145-C148 PolarHBondContact O-N 2.8Å; L145-L149 PolarHBondContact O-N 3.36Å; L145-P192 HydrophobicContact CD1-CB 3.72Å; L145-V195 HydrophobicContact CB-CB 4.34Å; L145-V195 HydrophobicContact CB-CG1 3.79Å; L145-V196 HydrophobicContact CD1-CG2 4.4Å; L145-F280 HydrophobicContact CD1-CE2 3.96Å; L145-F280 HydrophobicContact CD2-CE2 4.3Å; L145-F280 HydrophobicContact CD2-CZ 4.46Å; L145-L283 HydrophobicContact CB-CD2 4.11Å; L145-L283 HydrophobicContact CD2-CD2 4Å; L145-L283 HydrophobicContact CD2-CG 4.21Å; L145-K284 HydrophobicContact CD2-CG 3.86Å
146	L	98.4	Very high	89.6	Confident	1 Å²	1	50.2 Å²	50.2	1%	0.005	26%	0.258	C	S	.	.	H	α-helix	trans	-62.6	-40.4	173.5	-77	167.9	0	0	0	111.6	T142 E144 L149 G150 V169 L172 R173 I190 V195	T142-L146 HydrophobicContact CG2-CD1 4.08Å; T142-L146 HydrophobicContact CG2-CG 4.47Å; T142-L146 WeakPolarHBondContact O-CB 3.42Å; T142-L146 VanDerWaalsContact O-CG 3.25Å; T142-L146 WeakPolarHBondContact O-CG 3.43Å; T142-L146 PolarHBondContact O-N 3.42Å; E144-L146 PolarHBondContact O-N 3.14Å; L146-L149 PolarHBondContact O-N 3.42Å; L146-G150 PolarHBondContact O-N 3.38Å; L146-V169 HydrophobicContact CB-CG1 4.05Å; L146-V169 HydrophobicContact CB-CG2 3.98Å; L146-V169 HydrophobicContact CD1-CG1 4.2Å; L146-V169 WeakPolarHBondContact O-CG2 3.45Å; L146-L172 HydrophobicContact CD2-CD1 3.73Å; L146-R173 HydrophobicContact CD1-CG 4.49Å; L146-I190 HydrophobicContact CD1-CG2 3.8Å; L146-I190 HydrophobicContact CD2-CG2 4.16Å; L146-I190 HydrophobicContact CG-CG2 4.34Å; L146-V195 HydrophobicContact CD2-CG1 4.29Å; L146-V195 HydrophobicContact CD2-CG2 3.83Å; L146-V195 HydrophobicContact CG-CG1 4.47Å; L146-V195 HydrophobicContact CG-CG2 4Å
147	R	97.4	Very high	91.8	Very high	152 Å²	152	44.6 Å²	44.6	57%	0.574	22%	0.224	S	C	*	.	H	α-helix	trans	-62.8	-46.6	174.1	179.9	-180	172.4	154.5	1.6	111.3	S143 E144 L145 L149 G150 E151	S143-R147 WeakPolarHBondContact O-CB 3.31Å; S143-R147 PolarHBondContact O-N 3.01Å; E144-R147 WeakPolarHBondContact O-CB 3.39Å; E144-R147 PolarHBondContact O-N 2.96Å; L145-R147 VanDerWaalsContact C-N 3.31Å; R147-L149 VanDerWaalsContact C-N 3.26Å; R147-L149 PolarHBondContact O-N 3.12Å; R147-G150 PolarHBondContact O-N 3.46Å; R147-G150 VanDerWaalsContact O-N 3.09Å; R147-E151 HydrophobicContact CG-CG 4.48Å; R147-E151 IonicContact CZ-OE1 2.75Å; R147-E151 IonicContact NE-OE1 3.27Å; R147-E151 PolarHBondContact NE-OE1 3.2Å; R147-E151 IonicContact NH2-OE1 2.96Å; R147-E151 PolarHBondContact NH2-OE1 3.27Å; R147-E151 WeakPolarHBondContact O-CG 3.34Å; R147-E151 PolarHBondContact O-N 2.9Å
148	C	98.1	Very high	94	Very high	2 Å²	2	43.1 Å²	43.1	1%	0.014	21%	0.21	C	C	.	.	H	α-helix	trans	-57.8	-40.1	175.9	-64	0	0	0	0	111.8	E144 L145 F152 L283	E144-C148 PolarHBondContact O-N 2.81Å; E144-C148 PolarHBondContact O-SG 3.08Å; L145-C148 PolarHBondContact O-N 2.8Å; C148-F152 WeakPolarHBondContact O-CB 3.42Å; C148-F152 PolarHBondContact O-N 3.19Å; C148-L283 HydrophobicContact CB-CD1 3.7Å; C148-L283 HydrophobicContact CB-CG 4.12Å; C148-L283 VanDerWaalsContact CB-O 3.27Å; C148-L283 WeakPolarHBondContact CB-O 3.46Å
149	L	98.6	Very high	95.8	Very high	1 Å²	1	47 Å²	47	1%	0.005	22%	0.22	C	C	.	.	H	α-helix	trans	-64.6	-42.8	175	176.7	62.6	0	0	0	111.6	L145 L146 R147 F152 L153 L172 V195 V198 Y199 C202 L283	L145-L149 PolarHBondContact O-N 3.36Å; L146-L149 PolarHBondContact O-N 3.42Å; R147-L149 VanDerWaalsContact C-N 3.26Å; R147-L149 PolarHBondContact O-N 3.12Å; L149-F152 HydrophobicContact CD1-CD1 4.08Å; L149-F152 WeakPolarHBondContact O-CB 3.47Å; L149-F152 PolarHBondContact O-N 3.29Å; L149-L153 HydrophobicContact CD1-CD1 4.38Å; L149-L153 HydrophobicContact CD1-CG 4.39Å; L149-L153 HydrophobicContact CG-CD1 4.31Å; L149-L153 VanDerWaalsContact O-CG 3.31Å; L149-L153 WeakPolarHBondContact O-CG 3.13Å; L149-L153 PolarHBondContact O-N 3Å; L149-L172 HydrophobicContact CD2-CD1 3.75Å; L149-V195 HydrophobicContact CD2-CG1 4.43Å; L149-V198 HydrophobicContact CD2-CG1 4.01Å; L149-Y199 HydrophobicContact CD1-CD2 4.07Å; L149-C202 HydrophobicContact CD1-CB 4.39Å; L149-L283 HydrophobicContact CB-CD1 4.18Å
150	G	98.2	Very high	96.7	Very high	0 Å²	0	40.1 Å²	40.1	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-60.8	-46.8	175.7	0	0	0	0	0	112.8	L146 R147 L153 C154 P165	L146-G150 PolarHBondContact O-N 3.38Å; R147-G150 PolarHBondContact O-N 3.46Å; R147-G150 VanDerWaalsContact O-N 3.09Å; G150-L153 PolarHBondContact O-N 2.95Å; G150-C154 PolarHBondContact O-N 2.87Å; G150-C154 PolarHBondContact O-SG 3.08Å; G150-P165 WeakPolarHBondContact CA-O 3.49Å
151	E	97.5	Very high	97.1	Very high	8 Å²	8	47.1 Å²	47.1	4%	0.037	22%	0.216	C	C	.	.	H	α-helix	trans	-61.4	-43	175.3	-75.3	173.8	-178.4	0	0	111.5	R147 L153 C154 R155 P165 S287 E290	R147-E151 HydrophobicContact CG-CG 4.48Å; R147-E151 IonicContact CZ-OE1 2.75Å; R147-E151 IonicContact NE-OE1 3.27Å; R147-E151 PolarHBondContact NE-OE1 3.2Å; R147-E151 IonicContact NH2-OE1 2.96Å; R147-E151 PolarHBondContact NH2-OE1 3.27Å; R147-E151 WeakPolarHBondContact O-CG 3.34Å; R147-E151 PolarHBondContact O-N 2.9Å; E151-L153 PolarHBondContact O-N 2.74Å; E151-C154 PolarHBondContact O-N 3.26Å; E151-R155 WeakPolarHBondContact O-CB 3.47Å; E151-R155 PolarHBondContact O-N 3.29Å; E151-R155 PolarHBondContact O-NH2 3.24Å; E151-P165 HydrophobicContact CG-CB 3.91Å; E151-S287 WeakPolarHBondContact OE2-CA 3.41Å; E151-S287 WeakPolarHBondContact OE2-CB 3.45Å; E151-E290 WeakPolarHBondContact CB-OE2 3.41Å; E151-E290 WeakPolarHBondContact CG-OE2 3.31Å
152	F	98.3	Very high	97	Very high	5 Å²	5	52 Å²	52	2%	0.022	23%	0.232	C	C	.	.	H	α-helix	trans	-55	-49	171	163.4	-99.1	0	0	0	112.9	C148 L149 R155 R156 Y199 C202 R203 E286	C148-F152 WeakPolarHBondContact O-CB 3.42Å; C148-F152 PolarHBondContact O-N 3.19Å; L149-F152 HydrophobicContact CD1-CD1 4.08Å; L149-F152 WeakPolarHBondContact O-CB 3.47Å; L149-F152 PolarHBondContact O-N 3.29Å; F152-R155 PolarHBondContact O-N 3.22Å; F152-R156 HydrophobicContact CE2-CB 4.35Å; F152-R156 HydrophobicContact CZ-CB 4.17Å; F152-R156 HydrophobicContact CZ-CG 4.33Å; F152-R156 VanDerWaalsContact O-CB 3.32Å; F152-R156 WeakPolarHBondContact O-CB 3.29Å; F152-R156 PolarHBondContact O-N 2.86Å; F152-Y199 HydrophobicContact CB-CE2 4.38Å; F152-Y199 HydrophobicContact CD1-CD2 4.08Å; F152-Y199 HydrophobicContact CD1-CE2 4.06Å; F152-Y199 AromaticContact CD2-CE2 3.84Å; F152-Y199 HydrophobicContact CD2-CE2 3.84Å; F152-Y199 HydrophobicContact CE1-CD2 4.47Å; F152-Y199 HydrophobicContact CE1-CE2 4.42Å; F152-Y199 HydrophobicContact CE2-CE2 4.21Å; F152-Y199 HydrophobicContact CG-CD2 4.2Å; F152-Y199 AromaticContact CG-CE2 3.79Å; F152-Y199 HydrophobicContact CG-CE2 3.79Å; F152-C202 HydrophobicContact CE1-CB 4.09Å; F152-R203 HydrophobicContact CE2-CB 4.39Å; F152-R203 HydrophobicContact CZ-CB 4.03Å; F152-E286 HydrophobicContact CB-CB 4.09Å; F152-E286 HydrophobicContact CB-CG 3.92Å; F152-E286 HydrophobicContact CD2-CG 4.27Å; F152-E286 WeakPolarHBondContact CD2-OE1 3.32Å; F152-E286 HydrophobicContact CG-CG 4.45Å
153	L	98.3	Very high	97	Very high	0 Å²	0	51.3 Å²	51.3	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-66.4	-39.9	-178.6	-67.6	170.4	0	0	0	111.7	L149 G150 E151 R155 R156 C157 P168 C202 V206 L216 L220	L149-L153 HydrophobicContact CD1-CD1 4.38Å; L149-L153 HydrophobicContact CD1-CG 4.39Å; L149-L153 HydrophobicContact CG-CD1 4.31Å; L149-L153 VanDerWaalsContact O-CG 3.31Å; L149-L153 WeakPolarHBondContact O-CG 3.13Å; L149-L153 PolarHBondContact O-N 3Å; G150-L153 PolarHBondContact O-N 2.95Å; E151-L153 PolarHBondContact O-N 2.74Å; L153-R155 VanDerWaalsContact C-N 3.31Å; L153-R155 PolarHBondContact O-N 3.03Å; L153-R156 PolarHBondContact O-N 3.48Å; L153-C157 WeakPolarHBondContact O-CB 3.11Å; L153-C157 PolarHBondContact O-N 3.2Å; L153-P168 HydrophobicContact CB-CG 4.37Å; L153-P168 HydrophobicContact CD1-CB 3.63Å; L153-P168 HydrophobicContact CD1-CG 3.76Å; L153-C202 HydrophobicContact CD2-CB 4.34Å; L153-V206 HydrophobicContact CD2-CB 4.4Å; L153-V206 HydrophobicContact CD2-CG1 4.17Å; L153-V206 HydrophobicContact CD2-CG2 4.09Å; L153-L216 HydrophobicContact CD2-CD1 4.25Å; L153-L220 HydrophobicContact CD1-CD1 4.18Å; L153-L220 HydrophobicContact CD1-CD2 4Å
154	C	97	Very high	97	Very high	26 Å²	26	49.7 Å²	49.7	18%	0.176	22%	0.216	C	C	.	.	H	α-helix	trans	-60.3	-42	175	-65.1	0	0	0	0	112.1	G150 E151 P165	G150-C154 PolarHBondContact O-N 2.87Å; G150-C154 PolarHBondContact O-SG 3.08Å; E151-C154 PolarHBondContact O-N 3.26Å; C154-P165 VanDerWaalsContact SG-CA 3.58Å; C154-P165 VanDerWaalsContact SG-N 3.45Å
155	R	95.8	Very high	97	Very high	67 Å²	67	48 Å²	48	25%	0.253	21%	0.212	S	C	.	.	H	α-helix	trans	-71	-41	178.3	-169.5	-176.1	-46.6	98.9	21.1	112.6	E151 F152 L153 E286 E290	E151-R155 WeakPolarHBondContact O-CB 3.47Å; E151-R155 PolarHBondContact O-N 3.29Å; E151-R155 PolarHBondContact O-NH2 3.24Å; F152-R155 PolarHBondContact O-N 3.22Å; L153-R155 VanDerWaalsContact C-N 3.31Å; L153-R155 PolarHBondContact O-N 3.03Å; R155-E286 IonicContact CZ-OE2 3.77Å; R155-E286 PolarHBondContact NH1-O 3.31Å; R155-E286 IonicContact NH1-OE2 2.74Å; R155-E286 PolarHBondContact NH1-OE2 3.19Å; R155-E286 PolarHBondContact NH2-O 3.26Å; R155-E290 IonicContact NH2-OE2 2.72Å; R155-E290 PolarHBondContact NH2-OE2 3.01Å
156	R	97	Very high	97	Very high	74 Å²	74	52.2 Å²	52.2	28%	0.279	24%	0.237	S	C	.	.	H	α-helix	trans	-63.9	-50.2	178.5	177.4	59.2	63.8	82.1	-4.5	110.6	F152 L153 Y158 R203 V206 S208	F152-R156 HydrophobicContact CE2-CB 4.35Å; F152-R156 HydrophobicContact CZ-CB 4.17Å; F152-R156 HydrophobicContact CZ-CG 4.33Å; F152-R156 VanDerWaalsContact O-CB 3.32Å; F152-R156 WeakPolarHBondContact O-CB 3.29Å; F152-R156 PolarHBondContact O-N 2.86Å; L153-R156 PolarHBondContact O-N 3.48Å; R156-Y158 VanDerWaalsContact C-N 3.29Å; R156-Y158 PolarHBondContact O-N 2.98Å; R156-Y158 VanDerWaalsContact O-N 3.1Å; R156-R203 PolarHBondContact NH1-O 2.98Å; R156-R203 PolarHBondContact NH2-O 3.49Å; R156-R203 VanDerWaalsContact NH2-O 3.15Å; R156-V206 HydrophobicContact CG-CG1 4.24Å; R156-V206 PolarHBondContact NH1-O 2.86Å; R156-S208 VanDerWaalsContact O-CA 3.29Å; R156-S208 WeakPolarHBondContact O-CA 3.32Å; R156-S208 WeakPolarHBondContact O-CB 3.15Å
157	C	97.8	Very high	96.9	Very high	0 Å²	0	53.9 Å²	53.9	0%	0	25%	0.246	C	C	.	.			trans	-88.8	63	-176	-57.5	0	0	0	0	111.1	L153 R159 L160	L153-C157 WeakPolarHBondContact O-CB 3.11Å; L153-C157 PolarHBondContact O-N 3.2Å; C157-R159 PolarHBondContact O-N 2.88Å; C157-L160 HydrophobicContact CB-CD1 3.68Å; C157-L160 HydrophobicContact CB-CG 3.98Å; C157-L160 WeakPolarHBondContact O-CB 3.07Å; C157-L160 PolarHBondContact O-N 3.39Å
158	Y	95.8	Very high	97	Very high	109 Å²	109	46.7 Å²	46.7	43%	0.427	22%	0.219	S	C	.	.	T	Hydrogen-bonded Turn	trans	-58.2	-17.4	-172.3	69.5	-90.4	0	0	0	115.2	R156 K161 S208 E209	R156-Y158 VanDerWaalsContact C-N 3.29Å; R156-Y158 PolarHBondContact O-N 2.98Å; R156-Y158 VanDerWaalsContact O-N 3.1Å; Y158-K161 WeakPolarHBondContact O-CE 3.36Å; Y158-K161 PolarHBondContact O-NZ 2.99Å; Y158-S208 VanDerWaalsContact CD1-O 3.31Å; Y158-S208 WeakPolarHBondContact CD1-O 3.19Å; Y158-S208 WeakPolarHBondContact CE1-O 3.43Å; Y158-E209 WeakPolarHBondContact CE1-OE1 3.43Å; Y158-E209 VanDerWaalsContact OH-CD 3.22Å; Y158-E209 PolarHBondContact OH-OE1 2.96Å; Y158-E209 PolarHBondContact OH-OE2 3.28Å
159	R	97.3	Very high	97	Very high	122 Å²	122	48.2 Å²	48.2	46%	0.46	23%	0.228	S	C	.	.	T	Hydrogen-bonded Turn	trans	-76.9	-22.6	177.1	-60.8	177.5	66.5	-178	3.6	112.6	C157 K161 E209 A211	C157-R159 PolarHBondContact O-N 2.88Å; R159-K161 PolarHBondContact O-N 3.18Å; R159-K161 VanDerWaalsContact O-N 3.15Å; R159-E209 WeakPolarHBondContact CD-O 3.45Å; R159-E209 PolarHBondContact NH1-O 2.89Å; R159-A211 VanDerWaalsContact CZ-CB 3.48Å
160	L	96.8	Very high	97	Very high	19 Å²	19	53.6 Å²	53.6	10%	0.099	26%	0.257	C	S	.	.			trans	-84	85.7	-179.1	-55.7	-178	0	0	0	110.9	C157 H162 L163 V210 A211 T212 L216	C157-L160 HydrophobicContact CB-CD1 3.68Å; C157-L160 HydrophobicContact CB-CG 3.98Å; C157-L160 WeakPolarHBondContact O-CB 3.07Å; C157-L160 PolarHBondContact O-N 3.39Å; L160-H162 VanDerWaalsContact C-N 3.26Å; L160-H162 PolarHBondContact O-N 3.24Å; L160-L163 HydrophobicContact CB-CB 3.8Å; L160-L163 HydrophobicContact CB-CD2 4.43Å; L160-L163 HydrophobicContact CD1-CB 4.44Å; L160-L163 HydrophobicContact CD1-CD2 3.9Å; L160-V210 HydrophobicContact CD1-CG1 4.42Å; L160-A211 WeakPolarHBondContact CD2-O 3.48Å; L160-T212 VanDerWaalsContact CD2-C 3.4Å; L160-L216 HydrophobicContact CD1-CB 4.03Å; L160-L216 HydrophobicContact CD1-CD2 3.65Å; L160-L216 HydrophobicContact CD1-CG 4.46Å
161	K	93.3	Very high	97.1	Very high	160 Å²	160	55.2 Å²	55.2	70%	0.696	26%	0.263	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.9	-18.6	-175.4	-57.3	-52.2	-175.5	-169.3	0	114.8	Y158 R159	Y158-K161 WeakPolarHBondContact O-CE 3.36Å; Y158-K161 PolarHBondContact O-NZ 2.99Å; R159-K161 PolarHBondContact O-N 3.18Å; R159-K161 VanDerWaalsContact O-N 3.15Å
162	H	93.5	Very high	97.1	Very high	166 Å²	166	55 Å²	55	77%	0.769	26%	0.262	S	S	*	.	T	Hydrogen-bonded Turn	trans	-112.3	0.8	-175.1	-58.7	-57.1	0	0	0	113.6	L160 S164	L160-H162 VanDerWaalsContact C-N 3.26Å; L160-H162 PolarHBondContact O-N 3.24Å; H162-S164 PolarHBondContact O-N 3.38Å
163	L	96.4	Very high	97.1	Very high	16 Å²	16	59.7 Å²	59.7	8%	0.084	28%	0.279	C	S	.	.			trans	-67.3	122.1	176.5	-179.6	71	0	0	0	109.7	L160 D167 W171 E213 L216	L160-L163 HydrophobicContact CB-CB 3.8Å; L160-L163 HydrophobicContact CB-CD2 4.43Å; L160-L163 HydrophobicContact CD1-CB 4.44Å; L160-L163 HydrophobicContact CD1-CD2 3.9Å; L163-D167 HydrophobicContact CD1-CB 4.03Å; L163-W171 HydrophobicContact CD1-CH2 3.84Å; L163-E213 HydrophobicContact CD1-CG 4.26Å; L163-L216 HydrophobicContact CD1-CD2 4.15Å; L163-L216 HydrophobicContact CD2-CD2 3.38Å; L163-L216 HydrophobicContact CG-CD2 4.44Å
164	S	96.9	Very high	97.2	Very high	41 Å²	41	63.1 Å²	63.1	29%	0.287	30%	0.303	S	S	.	.			trans	-86.4	142.9	170.4	177.4	0	0	0	0	110	H162 T166 D167 P168	H162-S164 PolarHBondContact O-N 3.38Å; S164-T166 WeakPolarHBondContact CB-OG1 3.48Å; S164-T166 PolarHBondContact O-N 3.26Å; S164-T166 PolarHBondContact OG-N 3.47Å; S164-T166 PolarHBondContact OG-OG1 3.49Å; S164-D167 WeakPolarHBondContact CB-OD2 3.47Å; S164-D167 PolarHBondContact N-OD2 3.23Å; S164-D167 PolarHBondContact O-N 2.99Å; S164-P168 VanDerWaalsContact O-CD 3.29Å; S164-P168 WeakPolarHBondContact O-CD 3.44Å
165	P	95.9	Very high	97.2	Very high	40 Å²	40	62.2 Å²	62.2	26%	0.26	30%	0.297	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.8	-14.5	172.7	25.2	-34.4	0	0	0	112.8	G150 E151 C154	G150-P165 WeakPolarHBondContact CA-O 3.49Å; E151-P165 HydrophobicContact CG-CB 3.91Å; C154-P165 VanDerWaalsContact SG-CA 3.58Å; C154-P165 VanDerWaalsContact SG-N 3.45Å
166	T	97.9	Very high	97.4	Very high	87 Å²	87	59.7 Å²	59.7	53%	0.534	29%	0.288	S	S	.	.	H	α-helix	trans	-78.3	-22.8	173.3	57.8	0	0	0	0	114	S164 V169 L170	S164-T166 WeakPolarHBondContact CB-OG1 3.48Å; S164-T166 PolarHBondContact O-N 3.26Å; S164-T166 PolarHBondContact OG-N 3.47Å; S164-T166 PolarHBondContact OG-OG1 3.49Å; T166-V169 WeakPolarHBondContact O-CB 3.3Å; T166-V169 PolarHBondContact O-N 3.33Å; T166-L170 PolarHBondContact O-N 3.31Å
167	D	98.3	Very high	97.4	Very high	37 Å²	37	64 Å²	64	20%	0.198	31%	0.305	C	S	.	.	H	α-helix	trans	-68.6	-46.7	-172.4	-54.2	-30.8	0	0	0	111.8	L163 S164 V169 L170 W171	L163-D167 HydrophobicContact CD1-CB 4.03Å; S164-D167 WeakPolarHBondContact CB-OD2 3.47Å; S164-D167 PolarHBondContact N-OD2 3.23Å; S164-D167 PolarHBondContact O-N 2.99Å; D167-V169 VanDerWaalsContact C-N 3.26Å; D167-V169 PolarHBondContact O-N 3.34Å; D167-L170 WeakPolarHBondContact O-CB 3.34Å; D167-L170 PolarHBondContact O-N 2.92Å; D167-L170 VanDerWaalsContact O-N 3.13Å; D167-W171 HydrophobicContact CB-CH2 4.23Å; D167-W171 HydrophobicContact CB-CZ2 3.74Å; D167-W171 VanDerWaalsContact O-CD2 3.28Å; D167-W171 PolarHBondContact O-N 2.93Å
168	P	98.6	Very high	97.5	Very high	1 Å²	1	65.6 Å²	65.6	1%	0.006	32%	0.316	C	S	.	.	H	α-helix	trans	-56.8	-41.2	171.8	-26.2	37	0	0	0	112.4	L153 S164 L170 W171 L172 L220	L153-P168 HydrophobicContact CB-CG 4.37Å; L153-P168 HydrophobicContact CD1-CB 3.63Å; L153-P168 HydrophobicContact CD1-CG 3.76Å; S164-P168 VanDerWaalsContact O-CD 3.29Å; S164-P168 WeakPolarHBondContact O-CD 3.44Å; P168-L170 VanDerWaalsContact C-N 3.33Å; P168-L170 PolarHBondContact O-N 3.09Å; P168-W171 HydrophobicContact CB-CE3 4.41Å; P168-W171 HydrophobicContact CG-CZ3 4.25Å; P168-W171 PolarHBondContact O-N 3.02Å; P168-L172 VanDerWaalsContact O-CG 3.25Å; P168-L172 WeakPolarHBondContact O-CG 3.27Å; P168-L172 PolarHBondContact O-N 3.34Å; P168-L220 HydrophobicContact CB-CD2 3.84Å
169	V	98.6	Very high	97.6	Very high	34 Å²	34	60.4 Å²	60.4	21%	0.206	30%	0.295	C	S	.	.	H	α-helix	trans	-61	-44	178.4	-177.6	0	0	0	0	111	L146 T166 D167 L172 R173	L146-V169 HydrophobicContact CB-CG1 4.05Å; L146-V169 HydrophobicContact CB-CG2 3.98Å; L146-V169 HydrophobicContact CD1-CG1 4.2Å; L146-V169 WeakPolarHBondContact O-CG2 3.45Å; T166-V169 WeakPolarHBondContact O-CB 3.3Å; T166-V169 PolarHBondContact O-N 3.33Å; D167-V169 VanDerWaalsContact C-N 3.26Å; D167-V169 PolarHBondContact O-N 3.34Å; V169-L172 PolarHBondContact O-N 2.93Å; V169-R173 HydrophobicContact CG1-CG 4.25Å; V169-R173 WeakPolarHBondContact O-CB 3.39Å; V169-R173 VanDerWaalsContact O-CG 3.23Å; V169-R173 WeakPolarHBondContact O-CG 3.35Å; V169-R173 PolarHBondContact O-N 2.92Å
170	L	98.7	Very high	97.6	Very high	114 Å²	114	57.8 Å²	57.8	60%	0.597	29%	0.29	S	S	*	.	H	α-helix	trans	-63.5	-44	178.2	-176.8	64.3	0	0	0	111.4	T166 D167 P168 R173 S174	T166-L170 PolarHBondContact O-N 3.31Å; D167-L170 WeakPolarHBondContact O-CB 3.34Å; D167-L170 PolarHBondContact O-N 2.92Å; D167-L170 VanDerWaalsContact O-N 3.13Å; P168-L170 VanDerWaalsContact C-N 3.33Å; P168-L170 PolarHBondContact O-N 3.09Å; L170-R173 PolarHBondContact O-N 3.42Å; L170-S174 WeakPolarHBondContact O-CB 3.42Å; L170-S174 PolarHBondContact O-N 3.26Å
171	W	98.8	Very high	97.7	Very high	34 Å²	34	62.5 Å²	62.5	13%	0.129	32%	0.315	C	S	.	.	H	α-helix	trans	-61	-48.5	178.2	-55.5	-24.9	0	0	0	111.5	L163 D167 P168 S174 V175 L216 Q217 L220	L163-W171 HydrophobicContact CD1-CH2 3.84Å; D167-W171 HydrophobicContact CB-CH2 4.23Å; D167-W171 HydrophobicContact CB-CZ2 3.74Å; D167-W171 VanDerWaalsContact O-CD2 3.28Å; D167-W171 PolarHBondContact O-N 2.93Å; P168-W171 HydrophobicContact CB-CE3 4.41Å; P168-W171 HydrophobicContact CG-CZ3 4.25Å; P168-W171 PolarHBondContact O-N 3.02Å; W171-S174 PolarHBondContact O-N 2.94Å; W171-V175 PolarHBondContact O-N 2.84Å; W171-L216 HydrophobicContact CZ3-CD2 4.3Å; W171-L216 HydrophobicContact CZ3-CG 4.22Å; W171-Q217 VanDerWaalsContact CD1-NE2 3.25Å; W171-Q217 HydrophobicContact CD2-CB 4.15Å; W171-Q217 HydrophobicContact CD2-CG 3.73Å; W171-Q217 HydrophobicContact CE3-CB 3.86Å; W171-Q217 HydrophobicContact CE3-CG 3.81Å; W171-Q217 HydrophobicContact CG-CG 4.07Å; W171-Q217 HydrophobicContact CH2-CB 4.07Å; W171-Q217 HydrophobicContact CZ2-CB 4.32Å; W171-Q217 HydrophobicContact CZ3-CB 3.83Å; W171-Q217 HydrophobicContact CZ3-CG 4.3Å; W171-L220 HydrophobicContact CE3-CD2 3.99Å
172	L	98.8	Very high	97.9	Very high	3 Å²	3	60.4 Å²	60.4	2%	0.016	31%	0.308	C	S	.	.	H	α-helix	trans	-61.2	-48.6	178.6	-64	-179.8	0	0	0	111.8	L146 L149 P168 V169 S174 V175 D176 I190 L220 L224	L146-L172 HydrophobicContact CD2-CD1 3.73Å; L149-L172 HydrophobicContact CD2-CD1 3.75Å; P168-L172 VanDerWaalsContact O-CG 3.25Å; P168-L172 WeakPolarHBondContact O-CG 3.27Å; P168-L172 PolarHBondContact O-N 3.34Å; V169-L172 PolarHBondContact O-N 2.93Å; L172-S174 VanDerWaalsContact C-N 3.33Å; L172-S174 PolarHBondContact O-N 3.43Å; L172-V175 PolarHBondContact O-N 3.36Å; L172-D176 PolarHBondContact O-N 2.89Å; L172-D176 VanDerWaalsContact O-N 3.15Å; L172-I190 HydrophobicContact CB-CD1 4.4Å; L172-L220 HydrophobicContact CD2-CD1 4.28Å; L172-L220 HydrophobicContact CD2-CD2 4.1Å; L172-L220 HydrophobicContact CD2-CG 4.05Å; L172-L220 HydrophobicContact CG-CD2 4.28Å; L172-L224 HydrophobicContact CD2-CB 4.13Å; L172-L224 HydrophobicContact CD2-CD1 3.82Å; L172-L224 HydrophobicContact CD2-CD2 3.61Å; L172-L224 HydrophobicContact CD2-CG 4.01Å
173	R	98.6	Very high	98.1	Very high	104 Å²	104	55.5 Å²	55.5	39%	0.392	30%	0.302	S	S	.	.	H	α-helix	trans	-66.2	-34.4	179.8	-70.7	-70.9	-168	138.2	6.1	112.4	L146 V169 L170 R177	L146-R173 HydrophobicContact CD1-CG 4.49Å; V169-R173 HydrophobicContact CG1-CG 4.25Å; V169-R173 WeakPolarHBondContact O-CB 3.39Å; V169-R173 VanDerWaalsContact O-CG 3.23Å; V169-R173 WeakPolarHBondContact O-CG 3.35Å; V169-R173 PolarHBondContact O-N 2.92Å; L170-R173 PolarHBondContact O-N 3.42Å; R173-R177 WeakPolarHBondContact O-CB 3.32Å; R173-R177 PolarHBondContact O-N 3.13Å
174	S	98.7	Very high	98.2	Very high	72 Å²	72	59.8 Å²	59.8	50%	0.503	32%	0.317	S	S	.	.	H	α-helix	trans	-63	-45.3	177.3	-178.5	0	0	0	0	111.3	L170 W171 L172 S178	L170-S174 WeakPolarHBondContact O-CB 3.42Å; L170-S174 PolarHBondContact O-N 3.26Å; W171-S174 PolarHBondContact O-N 2.94Å; L172-S174 VanDerWaalsContact C-N 3.33Å; L172-S174 PolarHBondContact O-N 3.43Å; S174-S178 WeakPolarHBondContact O-CB 3.31Å; S174-S178 PolarHBondContact O-N 2.86Å
175	V	98.8	Very high	98.2	Very high	7 Å²	7	58.1 Å²	58.1	4%	0.042	30%	0.304	C	S	.	.	H	α-helix	trans	-62.3	-50.6	176.3	172.4	0	0	0	0	111.2	W171 L172 R177 S178 L179 L221 L224 Y228 P241 F242	W171-V175 PolarHBondContact O-N 2.84Å; L172-V175 PolarHBondContact O-N 3.36Å; V175-R177 VanDerWaalsContact C-N 3.32Å; V175-R177 PolarHBondContact O-N 3.36Å; V175-S178 WeakPolarHBondContact O-CB 3.38Å; V175-S178 PolarHBondContact O-N 3.14Å; V175-S178 VanDerWaalsContact O-N 3.08Å; V175-L179 HydrophobicContact CG1-CD1 4.06Å; V175-L179 WeakPolarHBondContact O-CG 3.48Å; V175-L179 PolarHBondContact O-N 3.3Å; V175-L221 HydrophobicContact CG2-CD2 3.82Å; V175-L224 HydrophobicContact CB-CD2 4.01Å; V175-L224 HydrophobicContact CG1-CD2 3.96Å; V175-L224 HydrophobicContact CG2-CD2 4.36Å; V175-Y228 HydrophobicContact CG1-CE2 4.42Å; V175-P241 HydrophobicContact CG1-CB 3.97Å; V175-P241 HydrophobicContact CG2-CB 4.4Å; V175-P241 VanDerWaalsContact CG2-O 3.31Å; V175-P241 WeakPolarHBondContact CG2-O 3.32Å; V175-F242 HydrophobicContact CG1-CD1 3.99Å; V175-F242 HydrophobicContact CG1-CE1 3.5Å; V175-F242 HydrophobicContact CG1-CE2 4.3Å; V175-F242 HydrophobicContact CG1-CZ 3.68Å
176	D	98.6	Very high	98.2	Very high	13 Å²	13	61.3 Å²	61.3	7%	0.07	32%	0.319	C	S	.	.	H	α-helix	trans	-60.4	-42.4	-178.4	-163.1	41.6	0	0	0	112.2	L172 L179 L180 Q185 G188 F189 I190 Y228	L172-D176 PolarHBondContact O-N 2.89Å; L172-D176 VanDerWaalsContact O-N 3.15Å; D176-L179 PolarHBondContact O-N 2.61Å; D176-L180 PolarHBondContact O-N 3.46Å; D176-L180 VanDerWaalsContact O-N 3.14Å; D176-Q185 PolarHBondContact O-NE2 3.32Å; D176-Q185 VanDerWaalsContact O-NE2 3.15Å; D176-Q185 PolarHBondContact OD1-NE2 2.98Å; D176-G188 WeakPolarHBondContact OD2-CA 3.44Å; D176-F189 WeakPolarHBondContact OD1-CB 3.3Å; D176-F189 PolarHBondContact OD1-N 2.88Å; D176-F189 PolarHBondContact OD2-N 3.11Å; D176-I190 HydrophobicContact CB-CG1 3.63Å; D176-I190 WeakPolarHBondContact OD2-CG1 3.49Å; D176-I190 PolarHBondContact OD2-N 3.49Å; D176-Y228 VanDerWaalsContact CA-OH 3.24Å; D176-Y228 WeakPolarHBondContact CA-OH 3.45Å; D176-Y228 WeakPolarHBondContact CB-OH 3.18Å; D176-Y228 VanDerWaalsContact CG-OH 3.24Å; D176-Y228 PolarHBondContact OD1-OH 2.86Å
177	R	98.5	Very high	98	Very high	165 Å²	165	62.2 Å²	62.2	62%	0.623	32%	0.317	S	S	*	.	H	α-helix	trans	-65	-40.6	174.7	-174.7	176.9	-175.6	-89.9	-0.9	112	R173 V175 L179 L180 L181	R173-R177 WeakPolarHBondContact O-CB 3.32Å; R173-R177 PolarHBondContact O-N 3.13Å; V175-R177 VanDerWaalsContact C-N 3.32Å; V175-R177 PolarHBondContact O-N 3.36Å; R177-L179 VanDerWaalsContact C-N 3.34Å; R177-L180 PolarHBondContact O-N 3.27Å; R177-L181 HydrophobicContact CG-CD1 3.95Å; R177-L181 HydrophobicContact CG-CG 4.35Å; R177-L181 WeakPolarHBondContact O-CB 3.44Å; R177-L181 WeakPolarHBondContact O-CG 3.29Å; R177-L181 PolarHBondContact O-N 3.44Å
178	S	98.6	Very high	97.9	Very high	33 Å²	33	61.5 Å²	61.5	23%	0.231	32%	0.319	C	S	.	.	H	α-helix	trans	-63.7	-40.2	178.5	-176.7	0	0	0	0	111.7	S174 V175 Q182	S174-S178 WeakPolarHBondContact O-CB 3.31Å; S174-S178 PolarHBondContact O-N 2.86Å; V175-S178 WeakPolarHBondContact O-CB 3.38Å; V175-S178 PolarHBondContact O-N 3.14Å; V175-S178 VanDerWaalsContact O-N 3.08Å; S178-Q182 WeakPolarHBondContact O-CB 3.48Å; S178-Q182 VanDerWaalsContact O-CG 3.28Å; S178-Q182 WeakPolarHBondContact O-CG 3.33Å; S178-Q182 PolarHBondContact O-N 2.94Å; S178-Q182 VanDerWaalsContact O-N 3.12Å; S178-Q182 PolarHBondContact OG-NE2 3.04Å; S178-Q182 VanDerWaalsContact OG-NE2 3.11Å
179	L	98.6	Very high	97.9	Very high	0 Å²	0	61.9 Å²	61.9	0%	0	32%	0.32	C	S	.	.	H	α-helix	trans	-65.8	-44.1	178	-70.2	170.1	0	0	0	111.4	V175 D176 R177 Q182 G183 W184 Q185 Y228 Y237 P238 P241 F242	V175-L179 HydrophobicContact CG1-CD1 4.06Å; V175-L179 WeakPolarHBondContact O-CG 3.48Å; V175-L179 PolarHBondContact O-N 3.3Å; D176-L179 PolarHBondContact O-N 2.61Å; R177-L179 VanDerWaalsContact C-N 3.34Å; L179-Q182 PolarHBondContact O-N 2.79Å; L179-G183 PolarHBondContact O-N 3.15Å; L179-W184 HydrophobicContact CB-CB 4.26Å; L179-W184 HydrophobicContact CD2-CB 3.8Å; L179-W184 HydrophobicContact CD2-CG 4.04Å; L179-W184 PolarHBondContact O-N 3.01Å; L179-Q185 HydrophobicContact CB-CG 4.05Å; L179-Y228 HydrophobicContact CD1-CD1 4.01Å; L179-Y228 HydrophobicContact CD1-CE1 3.44Å; L179-Y228 VanDerWaalsContact CD1-CE1 3.44Å; L179-Y228 HydrophobicContact CD1-CE2 4.38Å; L179-Y237 HydrophobicContact CD1-CD1 4.14Å; L179-P238 HydrophobicContact CD2-CG 3.64Å; L179-P241 HydrophobicContact CD2-CG 4.05Å; L179-F242 HydrophobicContact CD1-CE2 4.36Å; L179-F242 HydrophobicContact CD1-CZ 3.94Å
180	L	98	Very high	97.9	Very high	67 Å²	67	61.1 Å²	61.1	35%	0.351	32%	0.315	S	S	.	.	H	α-helix	trans	-58.7	-52.3	174.3	-81.9	164.3	0	0	0	112	D176 R177 Q182 G183 Q185	D176-L180 PolarHBondContact O-N 3.46Å; D176-L180 VanDerWaalsContact O-N 3.14Å; R177-L180 PolarHBondContact O-N 3.27Å; L180-Q182 PolarHBondContact O-N 3.09Å; L180-G183 PolarHBondContact O-N 3.4Å; L180-Q185 HydrophobicContact CD2-CG 3.97Å; L180-Q185 HydrophobicContact CG-CG 3.98Å
181	L	98.1	Very high	97.9	Very high	118 Å²	118	57.6 Å²	57.6	62%	0.618	30%	0.298	S	S	*	.	H	α-helix	trans	-67.3	-25.4	-175.4	-72.2	177.2	0	0	0	113.6	R177 G183	R177-L181 HydrophobicContact CG-CD1 3.95Å; R177-L181 HydrophobicContact CG-CG 4.35Å; R177-L181 WeakPolarHBondContact O-CB 3.44Å; R177-L181 WeakPolarHBondContact O-CG 3.29Å; R177-L181 PolarHBondContact O-N 3.44Å; L181-G183 VanDerWaalsContact C-N 3.34Å
182	Q	97.3	Very high	97.8	Very high	117 Å²	117	58.3 Å²	58.3	55%	0.547	31%	0.307	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.1	-0.2	176.8	-70	177.2	20.7	0	0	112.9	S178 L179 L180 W184	S178-Q182 WeakPolarHBondContact O-CB 3.48Å; S178-Q182 VanDerWaalsContact O-CG 3.28Å; S178-Q182 WeakPolarHBondContact O-CG 3.33Å; S178-Q182 PolarHBondContact O-N 2.94Å; S178-Q182 VanDerWaalsContact O-N 3.12Å; S178-Q182 PolarHBondContact OG-NE2 3.04Å; S178-Q182 VanDerWaalsContact OG-NE2 3.11Å; L179-Q182 PolarHBondContact O-N 2.79Å; L180-Q182 PolarHBondContact O-N 3.09Å; Q182-W184 VanDerWaalsContact C-N 3.34Å
183	G	97.6	Very high	97.7	Very high	62 Å²	62	58.7 Å²	58.7	64%	0.639	31%	0.311	S	S	*	.	T	Hydrogen-bonded Turn	trans	72.1	25.9	179	0	0	0	0	0	113.9	L179 L180 L181 Q185	L179-G183 PolarHBondContact O-N 3.15Å; L180-G183 PolarHBondContact O-N 3.4Å; L181-G183 VanDerWaalsContact C-N 3.34Å; G183-Q185 VanDerWaalsContact C-N 3.33Å
184	W	98.3	Very high	97.7	Very high	107 Å²	107	54.6 Å²	54.6	41%	0.405	30%	0.297	S	S	.	.	S	Bend	trans	-80.8	-16.3	173	-73.6	103.2	0	0	0	113	L179 Q182 E234 P238	L179-W184 HydrophobicContact CB-CB 4.26Å; L179-W184 HydrophobicContact CD2-CB 3.8Å; L179-W184 HydrophobicContact CD2-CG 4.04Å; L179-W184 PolarHBondContact O-N 3.01Å; Q182-W184 VanDerWaalsContact C-N 3.34Å; W184-E234 WeakPolarHBondContact O-CG 3.31Å; W184-P238 HydrophobicContact CD2-CB 4.31Å; W184-P238 HydrophobicContact CD2-CG 3.63Å; W184-P238 HydrophobicContact CE3-CG 4.15Å; W184-P238 HydrophobicContact CG-CG 3.88Å; W184-P238 HydrophobicContact CH2-CB 4.08Å; W184-P238 HydrophobicContact CH2-CG 4.45Å; W184-P238 HydrophobicContact CZ2-CB 3.79Å; W184-P238 HydrophobicContact CZ2-CG 3.99Å; W184-P238 HydrophobicContact CZ3-CB 4.46Å
185	Q	96.9	Very high	97.8	Very high	6 Å²	6	51.3 Å²	51.3	3%	0.028	27%	0.274	C	S	.	.			trans	-153.1	151.2	177.4	64.5	-174.1	7.2	0	0	109.9	D176 L179 L180 G183 Q187 E234 Y237	D176-Q185 PolarHBondContact O-NE2 3.32Å; D176-Q185 VanDerWaalsContact O-NE2 3.15Å; D176-Q185 PolarHBondContact OD1-NE2 2.98Å; L179-Q185 HydrophobicContact CB-CG 4.05Å; L180-Q185 HydrophobicContact CD2-CG 3.97Å; L180-Q185 HydrophobicContact CG-CG 3.98Å; G183-Q185 VanDerWaalsContact C-N 3.33Å; Q185-Q187 VanDerWaalsContact CD-O 3.3Å; Q185-Q187 WeakPolarHBondContact CG-O 3.32Å; Q185-E234 HydrophobicContact CB-CG 3.96Å; Q185-Y237 HydrophobicContact CB-CE1 4.49Å
186	D	95.9	Very high	97.7	Very high	107 Å²	107	51 Å²	51	57%	0.572	27%	0.272	S	S	*	.	S	Bend	trans	-88.6	-28.1	178.3	-69.3	-32.4	0	0	0	112.9
187	Q	94.9	Very high	97.8	Very high	105 Å²	105	50.5 Å²	50.5	49%	0.491	27%	0.269	S	S	.	.	S	Bend	trans	-127.3	146	-179.6	-175	175.6	-11.5	0	0	110.4	Q185	Q185-Q187 VanDerWaalsContact CD-O 3.3Å; Q185-Q187 WeakPolarHBondContact CG-O 3.32Å
188	G	95.8	Very high	97.8	Very high	22 Å²	22	42.7 Å²	42.7	23%	0.227	24%	0.24	C	C	.	.			trans	-64.1	135.2	175.8	0	0	0	0	0	111.7	D176 I190	D176-G188 WeakPolarHBondContact OD2-CA 3.44Å; G188-I190 VanDerWaalsContact C-N 3.32Å
189	F	98.4	Very high	97.8	Very high	10 Å²	10	41.5 Å²	41.5	4%	0.044	23%	0.23	C	C	.	.	S	Bend	trans	-72.9	-27.9	177.8	172.9	-98.6	0	0	0	112.1	D176 T191 N194 L224 S227 Y228 M231	D176-F189 WeakPolarHBondContact OD1-CB 3.3Å; D176-F189 PolarHBondContact OD1-N 2.88Å; D176-F189 PolarHBondContact OD2-N 3.11Å; F189-T191 PolarHBondContact O-N 2.96Å; F189-N194 HydrophobicContact CD1-CB 4.37Å; F189-N194 WeakPolarHBondContact CD2-ND2 3.46Å; F189-N194 HydrophobicContact CE1-CB 3.88Å; F189-N194 HydrophobicContact CE2-CB 4.23Å; F189-N194 WeakPolarHBondContact CE2-ND2 3.46Å; F189-N194 HydrophobicContact CZ-CB 3.78Å; F189-N194 WeakPolarHBondContact O-CB 3.35Å; F189-N194 PolarHBondContact O-ND2 3.15Å; F189-L224 HydrophobicContact CD1-CD1 4.45Å; F189-L224 HydrophobicContact CE1-CD1 4.18Å; F189-S227 VanDerWaalsContact CZ-C 3.5Å; F189-S227 WeakPolarHBondContact CZ-O 3.33Å; F189-Y228 HydrophobicContact CB-CD1 3.89Å; F189-Y228 HydrophobicContact CB-CE1 3.16Å; F189-Y228 HydrophobicContact CB-CE2 4.29Å; F189-Y228 WeakPolarHBondContact CB-OH 3.42Å; F189-Y228 HydrophobicContact CD1-CD1 4.23Å; F189-Y228 AromaticContact CD1-CD2 3.9Å; F189-Y228 HydrophobicContact CD1-CD2 3.9Å; F189-Y228 AromaticContact CD1-CE1 3.91Å; F189-Y228 HydrophobicContact CD1-CE1 3.91Å; F189-Y228 AromaticContact CD1-CE2 3.54Å; F189-Y228 HydrophobicContact CD1-CE2 3.54Å; F189-Y228 HydrophobicContact CD1-CG 4.24Å; F189-Y228 AromaticContact CD1-CZ 3.54Å; F189-Y228 AromaticContact CD2-CD1 3.94Å; F189-Y228 HydrophobicContact CD2-CD1 3.94Å; F189-Y228 HydrophobicContact CD2-CE1 4.1Å; F189-Y228 HydrophobicContact CD2-CG 4.31Å; F189-Y228 HydrophobicContact CE1-CD2 4.1Å; F189-Y228 HydrophobicContact CE1-CE2 4.11Å; F189-Y228 HydrophobicContact CE1-CG 4.48Å; F189-Y228 AromaticContact CG-CD1 3.76Å; F189-Y228 HydrophobicContact CG-CD1 3.76Å; F189-Y228 HydrophobicContact CG-CD2 4.27Å; F189-Y228 AromaticContact CG-CE1 3.47Å; F189-Y228 HydrophobicContact CG-CE1 3.47Å; F189-Y228 VanDerWaalsContact CG-CE1 3.47Å; F189-Y228 HydrophobicContact CG-CE2 4.01Å; F189-Y228 HydrophobicContact CG-CG 4.16Å; F189-Y228 AromaticContact CG-CZ 3.59Å; F189-M231 HydrophobicContact CE2-CB 3.88Å; F189-M231 HydrophobicContact CZ-CB 4.21Å
190	I	98.4	Very high	97.8	Very high	17 Å²	17	41.5 Å²	41.5	9%	0.087	23%	0.23	C	C	.	.			trans	-74.3	89.4	-173.3	-57.6	-67.9	0	0	0	110.2	T142 L146 L172 D176 G188 V195 L224	T142-I190 HydrophobicContact CG2-CG2 3.71Å; T142-I190 WeakPolarHBondContact CG2-O 3.43Å; L146-I190 HydrophobicContact CD1-CG2 3.8Å; L146-I190 HydrophobicContact CD2-CG2 4.16Å; L146-I190 HydrophobicContact CG-CG2 4.34Å; L172-I190 HydrophobicContact CB-CD1 4.4Å; D176-I190 HydrophobicContact CB-CG1 3.63Å; D176-I190 WeakPolarHBondContact OD2-CG1 3.49Å; D176-I190 PolarHBondContact OD2-N 3.49Å; G188-I190 VanDerWaalsContact C-N 3.32Å; I190-V195 HydrophobicContact CG2-CG2 4.03Å; I190-L224 HydrophobicContact CD1-CD1 4.27Å
191	T	97.9	Very high	97.8	Very high	40 Å²	40	38.3 Å²	38.3	25%	0.245	21%	0.214	C	C	.	.			trans	-118.2	164.6	176.3	66.6	0	0	0	0	110.3	F189 A193 N194 V195	F189-T191 PolarHBondContact O-N 2.96Å; T191-A193 VanDerWaalsContact C-N 3.34Å; T191-A193 PolarHBondContact O-N 2.96Å; T191-N194 PolarHBondContact O-N 3.26Å; T191-N194 PolarHBondContact OG1-N 2.98Å; T191-N194 PolarHBondContact OG1-ND2 3.23Å; T191-V195 WeakPolarHBondContact O-CG2 3.4Å; T191-V195 PolarHBondContact O-N 3.47Å
192	P	97.9	Very high	97.9	Very high	49 Å²	49	32.7 Å²	32.7	32%	0.318	18%	0.184	S	C	.	.	H	α-helix	trans	-54.5	-46.5	179.7	-28.4	37.6	0	0	0	113.5	T142 L145 N194 V195 V196	T142-P192 VanDerWaalsContact OG1-CD 3.31Å; T142-P192 WeakPolarHBondContact OG1-CD 3.38Å; T142-P192 WeakPolarHBondContact OG1-CG 3.43Å; L145-P192 HydrophobicContact CD1-CB 3.72Å; P192-N194 PolarHBondContact O-N 3.25Å; P192-V195 PolarHBondContact O-N 2.87Å; P192-V196 WeakPolarHBondContact O-CG2 3.46Å; P192-V196 PolarHBondContact O-N 3.31Å; P192-V196 VanDerWaalsContact O-N 3.15Å
193	A	97	Very high	97.9	Very high	12 Å²	12	28.9 Å²	28.9	10%	0.099	17%	0.165	C	C	.	.	H	α-helix	trans	-63.2	-41.6	179.4	0	0	0	0	0	112.5	A93 T191 V195 V196 F197 F276	A93-A193 HydrophobicContact CB-CB 3.84Å; T191-A193 VanDerWaalsContact C-N 3.34Å; T191-A193 PolarHBondContact O-N 2.96Å; A193-V195 PolarHBondContact O-N 2.94Å; A193-V196 WeakPolarHBondContact O-CB 3.48Å; A193-V196 PolarHBondContact O-N 3.01Å; A193-F197 PolarHBondContact O-N 3.34Å; A193-F276 HydrophobicContact CB-CE2 4.08Å; A193-F276 HydrophobicContact CB-CZ 4.06Å
194	N	98.6	Very high	98	Very high	18 Å²	18	29 Å²	29	10%	0.096	15%	0.151	C	C	.	.	H	α-helix	trans	-71.3	-30.8	179.9	-69.2	-14.3	0	0	0	112.3	F189 T191 P192 F197 V198	F189-N194 HydrophobicContact CD1-CB 4.37Å; F189-N194 WeakPolarHBondContact CD2-ND2 3.46Å; F189-N194 HydrophobicContact CE1-CB 3.88Å; F189-N194 HydrophobicContact CE2-CB 4.23Å; F189-N194 WeakPolarHBondContact CE2-ND2 3.46Å; F189-N194 HydrophobicContact CZ-CB 3.78Å; F189-N194 WeakPolarHBondContact O-CB 3.35Å; F189-N194 PolarHBondContact O-ND2 3.15Å; T191-N194 PolarHBondContact O-N 3.26Å; T191-N194 PolarHBondContact OG1-N 2.98Å; T191-N194 PolarHBondContact OG1-ND2 3.23Å; P192-N194 PolarHBondContact O-N 3.25Å; N194-F197 WeakPolarHBondContact O-CB 3.26Å; N194-F197 PolarHBondContact O-N 3.18Å; N194-V198 VanDerWaalsContact O-CG2 3.31Å; N194-V198 WeakPolarHBondContact O-CG2 3.3Å; N194-V198 PolarHBondContact O-N 3.06Å
195	V	98.8	Very high	98	Very high	2 Å²	2	25.4 Å²	25.4	1%	0.012	14%	0.141	C	C	.	.	H	α-helix	trans	-66.8	-38.9	172.4	176.6	0	0	0	0	111.2	T142 L145 L146 L149 I190 T191 P192 A193 F197 V198 Y199 L283	T142-V195 HydrophobicContact CG2-CG2 4.16Å; L145-V195 HydrophobicContact CB-CB 4.34Å; L145-V195 HydrophobicContact CB-CG1 3.79Å; L146-V195 HydrophobicContact CD2-CG1 4.29Å; L146-V195 HydrophobicContact CD2-CG2 3.83Å; L146-V195 HydrophobicContact CG-CG1 4.47Å; L146-V195 HydrophobicContact CG-CG2 4Å; L149-V195 HydrophobicContact CD2-CG1 4.43Å; I190-V195 HydrophobicContact CG2-CG2 4.03Å; T191-V195 WeakPolarHBondContact O-CG2 3.4Å; T191-V195 PolarHBondContact O-N 3.47Å; P192-V195 PolarHBondContact O-N 2.87Å; A193-V195 PolarHBondContact O-N 2.94Å; V195-F197 VanDerWaalsContact C-N 3.32Å; V195-F197 PolarHBondContact O-N 2.72Å; V195-V198 PolarHBondContact O-N 2.75Å; V195-Y199 WeakPolarHBondContact O-CB 3.25Å; V195-Y199 PolarHBondContact O-N 3.41Å; V195-L283 HydrophobicContact CG1-CD2 4.08Å
196	V	98.6	Very high	98.1	Very high	0 Å²	0	25.3 Å²	25.3	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-61.4	-42.4	172.7	177.3	0	0	0	0	110.9	L145 P192 A193 Y199 M200 I269 F276 V279 F280 L283	L145-V196 HydrophobicContact CD1-CG2 4.4Å; P192-V196 WeakPolarHBondContact O-CG2 3.46Å; P192-V196 PolarHBondContact O-N 3.31Å; P192-V196 VanDerWaalsContact O-N 3.15Å; A193-V196 WeakPolarHBondContact O-CB 3.48Å; A193-V196 PolarHBondContact O-N 3.01Å; V196-Y199 PolarHBondContact O-N 3.31Å; V196-M200 PolarHBondContact O-N 3.16Å; V196-I269 HydrophobicContact CG1-CD1 4.23Å; V196-F276 HydrophobicContact CB-CE2 4.06Å; V196-F276 HydrophobicContact CB-CZ 4.41Å; V196-F276 HydrophobicContact CG1-CD2 4.23Å; V196-F276 HydrophobicContact CG1-CE2 3.94Å; V196-F276 HydrophobicContact CG1-CZ 4.42Å; V196-F276 HydrophobicContact CG2-CE2 4.48Å; V196-F276 HydrophobicContact CG2-CZ 4.34Å; V196-V279 HydrophobicContact CG1-CB 3.93Å; V196-V279 HydrophobicContact CG1-CG1 3.58Å; V196-F280 HydrophobicContact CG1-CB 4.26Å; V196-F280 HydrophobicContact CG2-CB 4.09Å; V196-F280 HydrophobicContact CG2-CD2 3.61Å; V196-F280 HydrophobicContact CG2-CE2 4.5Å; V196-F280 HydrophobicContact CG2-CG 4.25Å; V196-L283 HydrophobicContact CG2-CD2 4.23Å
197	F	98.8	Very high	98.1	Very high	3 Å²	3	23.1 Å²	23.1	1%	0.013	13%	0.133	C	C	.	.	H	α-helix	trans	-62.2	-45.4	175.7	-170.2	-83.2	0	0	0	112	A193 N194 V195 Y199 M200 L201 Y230 M231 M266 I269	A193-F197 PolarHBondContact O-N 3.34Å; N194-F197 WeakPolarHBondContact O-CB 3.26Å; N194-F197 PolarHBondContact O-N 3.18Å; V195-F197 VanDerWaalsContact C-N 3.32Å; V195-F197 PolarHBondContact O-N 2.72Å; F197-Y199 VanDerWaalsContact C-N 3.35Å; F197-Y199 PolarHBondContact O-N 3.15Å; F197-M200 HydrophobicContact CD2-CE 4.43Å; F197-M200 HydrophobicContact CE2-CE 4.23Å; F197-M200 HydrophobicContact CZ-CE 4.42Å; F197-M200 WeakPolarHBondContact O-CB 3.46Å; F197-M200 PolarHBondContact O-N 3.25Å; F197-L201 HydrophobicContact CD1-CD1 4.37Å; F197-L201 HydrophobicContact CE1-CD1 4.01Å; F197-L201 HydrophobicContact CE1-CG 4.31Å; F197-L201 PolarHBondContact O-N 2.84Å; F197-Y230 AromaticContact CE2-CD1 3.89Å; F197-Y230 HydrophobicContact CE2-CD1 3.89Å; F197-Y230 HydrophobicContact CE2-CE1 4.15Å; F197-Y230 AromaticContact CZ-CD1 3.6Å; F197-Y230 HydrophobicContact CZ-CD1 3.6Å; F197-Y230 HydrophobicContact CZ-CE1 4.2Å; F197-Y230 HydrophobicContact CZ-CG 4.13Å; F197-M231 HydrophobicContact CD1-CG 4Å; F197-M231 HydrophobicContact CD2-CE 4.41Å; F197-M231 HydrophobicContact CD2-CG 3.74Å; F197-M231 HydrophobicContact CD2-SD 3.87Å; F197-M231 HydrophobicContact CE1-CG 4.04Å; F197-M231 HydrophobicContact CE2-CG 3.8Å; F197-M231 HydrophobicContact CE2-SD 3.83Å; F197-M231 HydrophobicContact CG-CG 3.84Å; F197-M231 HydrophobicContact CZ-CG 3.94Å; F197-M231 HydrophobicContact CZ-SD 4.44Å; F197-M266 HydrophobicContact CE1-CE 4.32Å; F197-M266 HydrophobicContact CE1-CG 4.42Å; F197-M266 HydrophobicContact CE2-CB 4.18Å; F197-M266 HydrophobicContact CE2-CG 4.36Å; F197-M266 HydrophobicContact CZ-CB 3.86Å; F197-M266 HydrophobicContact CZ-CE 3.91Å; F197-M266 HydrophobicContact CZ-CG 3.7Å; F197-I269 HydrophobicContact CD2-CG2 3.57Å; F197-I269 HydrophobicContact CE2-CG2 3.65Å
198	V	98.9	Very high	98.3	Very high	2 Å²	2	20.3 Å²	20.3	1%	0.012	13%	0.125	C	C	.	.	H	α-helix	trans	-61	-43.8	175.5	171.9	0	0	0	0	110.9	L149 N194 V195 M200 L201 C202 L220 L224 S227	L149-V198 HydrophobicContact CD2-CG1 4.01Å; N194-V198 VanDerWaalsContact O-CG2 3.31Å; N194-V198 WeakPolarHBondContact O-CG2 3.3Å; N194-V198 PolarHBondContact O-N 3.06Å; V195-V198 PolarHBondContact O-N 2.75Å; V198-M200 VanDerWaalsContact C-N 3.33Å; V198-M200 PolarHBondContact O-N 2.96Å; V198-L201 PolarHBondContact O-N 3.42Å; V198-C202 PolarHBondContact O-N 2.88Å; V198-C202 PolarHBondContact O-SG 2.98Å; V198-L220 HydrophobicContact CG1-CD1 4.33Å; V198-L224 HydrophobicContact CG2-CD1 3.98Å; V198-S227 WeakPolarHBondContact CG2-OG 3.34Å
199	Y	98.9	Very high	98.3	Very high	8 Å²	8	23.5 Å²	23.5	3%	0.031	13%	0.134	C	C	.	.	H	α-helix	trans	-60	-42.1	175.1	168	-105.6	0	0	0	112.2	L149 F152 V195 V196 F197 L201 C202 R203 V279 D282 L283 E286	L149-Y199 HydrophobicContact CD1-CD2 4.07Å; F152-Y199 HydrophobicContact CB-CE2 4.38Å; F152-Y199 HydrophobicContact CD1-CD2 4.08Å; F152-Y199 HydrophobicContact CD1-CE2 4.06Å; F152-Y199 AromaticContact CD2-CE2 3.84Å; F152-Y199 HydrophobicContact CD2-CE2 3.84Å; F152-Y199 HydrophobicContact CE1-CD2 4.47Å; F152-Y199 HydrophobicContact CE1-CE2 4.42Å; F152-Y199 HydrophobicContact CE2-CE2 4.21Å; F152-Y199 HydrophobicContact CG-CD2 4.2Å; F152-Y199 AromaticContact CG-CE2 3.79Å; F152-Y199 HydrophobicContact CG-CE2 3.79Å; V195-Y199 WeakPolarHBondContact O-CB 3.25Å; V195-Y199 PolarHBondContact O-N 3.41Å; V196-Y199 PolarHBondContact O-N 3.31Å; F197-Y199 VanDerWaalsContact C-N 3.35Å; F197-Y199 PolarHBondContact O-N 3.15Å; Y199-L201 VanDerWaalsContact C-N 3.26Å; Y199-L201 PolarHBondContact O-N 3.27Å; Y199-C202 PolarHBondContact O-N 3.07Å; Y199-C202 VanDerWaalsContact O-N 3.11Å; Y199-R203 HydrophobicContact CE2-CB 4.31Å; Y199-R203 PolarHBondContact O-N 3.42Å; Y199-V279 HydrophobicContact CD1-CG1 3.68Å; Y199-V279 HydrophobicContact CE1-CG1 4.03Å; Y199-D282 HydrophobicContact CE1-CB 4.03Å; Y199-L283 HydrophobicContact CD1-CB 3.73Å; Y199-L283 HydrophobicContact CD1-CD1 4.34Å; Y199-L283 HydrophobicContact CD1-CG 4.41Å; Y199-L283 HydrophobicContact CD2-CD1 3.68Å; Y199-L283 HydrophobicContact CE1-CB 3.89Å; Y199-L283 HydrophobicContact CE2-CD1 4.14Å; Y199-L283 HydrophobicContact CG-CB 4.06Å; Y199-L283 HydrophobicContact CG-CD1 3.77Å; Y199-L283 HydrophobicContact CG-CD2 4.27Å; Y199-L283 HydrophobicContact CG-CG 4.24Å; Y199-E286 HydrophobicContact CE2-CG 4.08Å; Y199-E286 PolarHBondContact OH-OE1 3.47Å
200	M	98.8	Very high	98.3	Very high	0 Å²	0	23.2 Å²	23.2	0%	0	13%	0.133	C	C	.	.	H	α-helix	trans	-56.7	-39.9	176.5	-173	-83.8	-65.6	0	0	112	V196 F197 V198 R203 M262 K265 M266 I269 V279	V196-M200 PolarHBondContact O-N 3.16Å; F197-M200 HydrophobicContact CD2-CE 4.43Å; F197-M200 HydrophobicContact CE2-CE 4.23Å; F197-M200 HydrophobicContact CZ-CE 4.42Å; F197-M200 WeakPolarHBondContact O-CB 3.46Å; F197-M200 PolarHBondContact O-N 3.25Å; V198-M200 VanDerWaalsContact C-N 3.33Å; V198-M200 PolarHBondContact O-N 2.96Å; M200-R203 WeakPolarHBondContact O-CG 3.25Å; M200-M262 HydrophobicContact CE-CE 4.48Å; M200-M262 WeakPolarHBondContact O-CE 3.41Å; M200-M262 HydrophobicContact SD-CE 3.29Å; M200-M262 WeakPolarHBondContact SD-CE 3.3Å; M200-K265 HydrophobicContact CE-CB 4.24Å; M200-K265 HydrophobicContact SD-CB 3.61Å; M200-K265 HydrophobicContact SD-CD 4.4Å; M200-M266 HydrophobicContact CE-CB 4.44Å; M200-M266 HydrophobicContact CE-CG 3.91Å; M200-I269 HydrophobicContact CB-CD1 4.05Å; M200-I269 HydrophobicContact CE-CG2 4.15Å; M200-I269 HydrophobicContact CG-CD1 4.07Å; M200-V279 HydrophobicContact CB-CG1 3.94Å; M200-V279 HydrophobicContact CG-CG1 4.42Å; M200-V279 HydrophobicContact CG-CG2 4.45Å
201	L	98.9	Very high	98.1	Very high	0 Å²	0	24.2 Å²	24.2	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-68	-51.7	172	-62.1	-178.2	0	0	0	111.2	F197 V198 Y199 R203 D204 V205 C223 S227 M262 M266	F197-L201 HydrophobicContact CD1-CD1 4.37Å; F197-L201 HydrophobicContact CE1-CD1 4.01Å; F197-L201 HydrophobicContact CE1-CG 4.31Å; F197-L201 PolarHBondContact O-N 2.84Å; V198-L201 PolarHBondContact O-N 3.42Å; Y199-L201 VanDerWaalsContact C-N 3.26Å; Y199-L201 PolarHBondContact O-N 3.27Å; L201-R203 VanDerWaalsContact C-N 3.29Å; L201-R203 PolarHBondContact O-N 3.08Å; L201-D204 PolarHBondContact O-N 3.5Å; L201-V205 VanDerWaalsContact O-CB 3.3Å; L201-V205 WeakPolarHBondContact O-CB 3.25Å; L201-V205 VanDerWaalsContact O-CG2 3.26Å; L201-V205 WeakPolarHBondContact O-CG2 3.23Å; L201-V205 PolarHBondContact O-N 3.37Å; L201-C223 HydrophobicContact CB-CB 4.12Å; L201-C223 HydrophobicContact CD1-CB 4.21Å; L201-C223 WeakPolarHBondContact CD1-O 3.42Å; L201-S227 WeakPolarHBondContact CD1-OG 3.29Å; L201-M262 HydrophobicContact CD2-CB 3.73Å; L201-M262 HydrophobicContact CD2-CE 4.13Å; L201-M262 HydrophobicContact CD2-CG 3.93Å; L201-M266 HydrophobicContact CD2-CG 3.85Å; L201-M266 HydrophobicContact CD2-SD 4.11Å
202	C	98.8	Very high	98.1	Very high	0 Å²	0	25.7 Å²	25.7	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-60.8	-36.5	-173.2	-65.7	0	0	0	0	112.9	L149 F152 L153 V198 Y199 D204 V205 V206 L220	L149-C202 HydrophobicContact CD1-CB 4.39Å; F152-C202 HydrophobicContact CE1-CB 4.09Å; L153-C202 HydrophobicContact CD2-CB 4.34Å; V198-C202 PolarHBondContact O-N 2.88Å; V198-C202 PolarHBondContact O-SG 2.98Å; Y199-C202 PolarHBondContact O-N 3.07Å; Y199-C202 VanDerWaalsContact O-N 3.11Å; C202-D204 PolarHBondContact O-N 3.02Å; C202-V205 PolarHBondContact O-N 3.29Å; C202-V206 HydrophobicContact CB-CG2 4.02Å; C202-V206 VanDerWaalsContact O-CB 3.3Å; C202-V206 WeakPolarHBondContact O-CB 3.23Å; C202-V206 PolarHBondContact O-N 3.48Å; C202-L220 WeakPolarHBondContact SG-CD1 3.37Å
203	R	98.3	Very high	98.1	Very high	37 Å²	37	27 Å²	27	14%	0.14	16%	0.155	C	C	.	.	H	α-helix	trans	-64	-26.8	-177.5	70.9	179.8	-175.3	175.3	2	114.2	F152 R156 Y199 M200 L201 Y275 V279 D282	F152-R203 HydrophobicContact CE2-CB 4.39Å; F152-R203 HydrophobicContact CZ-CB 4.03Å; R156-R203 PolarHBondContact NH1-O 2.98Å; R156-R203 PolarHBondContact NH2-O 3.49Å; R156-R203 VanDerWaalsContact NH2-O 3.15Å; Y199-R203 HydrophobicContact CE2-CB 4.31Å; Y199-R203 PolarHBondContact O-N 3.42Å; M200-R203 WeakPolarHBondContact O-CG 3.25Å; L201-R203 VanDerWaalsContact C-N 3.29Å; L201-R203 PolarHBondContact O-N 3.08Å; R203-Y275 PolarHBondContact NH2-OH 2.78Å; R203-V279 VanDerWaalsContact NH2-CG2 3.35Å; R203-D282 IonicContact NH1-OD2 3.78Å; R203-D282 PolarHBondContact NH1-OD2 3.39Å
204	D	98.3	Very high	98.2	Very high	65 Å²	65	31 Å²	31	35%	0.348	17%	0.172	S	C	.	.	H	α-helix	trans	-105.3	-24.3	-179.7	-65.3	-25.5	0	0	0	112.9	L201 C202 M262 K265	L201-D204 PolarHBondContact O-N 3.5Å; C202-D204 PolarHBondContact O-N 3.02Å; D204-M262 HydrophobicContact CB-CE 3.95Å; D204-M262 HydrophobicContact CB-SD 3.68Å; D204-M262 WeakPolarHBondContact OD2-CE 3.41Å; D204-K265 IonicContact OD1-NZ 2.79Å; D204-K265 IonicContact OD2-NZ 3.38Å; D204-K265 PolarHBondContact OD2-NZ 3.2Å
205	V	98.6	Very high	98.1	Very high	31 Å²	31	34 Å²	34	19%	0.188	19%	0.185	C	C	.	.	H	α-helix	trans	-94.4	-38.1	-176.8	174.3	0	0	0	0	113	L201 C202 S207 V219 I258 L261 M262	L201-V205 VanDerWaalsContact O-CB 3.3Å; L201-V205 WeakPolarHBondContact O-CB 3.25Å; L201-V205 VanDerWaalsContact O-CG2 3.26Å; L201-V205 WeakPolarHBondContact O-CG2 3.23Å; L201-V205 PolarHBondContact O-N 3.37Å; C202-V205 PolarHBondContact O-N 3.29Å; V205-S207 PolarHBondContact O-N 2.84Å; V205-V219 HydrophobicContact CG1-CG1 3.82Å; V205-I258 HydrophobicContact CB-CG1 4.48Å; V205-I258 HydrophobicContact CG1-CD1 3.71Å; V205-I258 HydrophobicContact CG1-CG1 3.67Å; V205-I258 HydrophobicContact CG2-CB 4.44Å; V205-I258 HydrophobicContact CG2-CD1 4.49Å; V205-I258 HydrophobicContact CG2-CG1 3.9Å; V205-I258 HydrophobicContact CG2-CG2 3.92Å; V205-L261 HydrophobicContact CG2-CD2 4.46Å; V205-M262 HydrophobicContact CG2-CG 3.95Å; V205-M262 HydrophobicContact CG2-SD 4.45Å
206	V	98.5	Very high	98.1	Very high	3 Å²	3	33.9 Å²	33.9	2%	0.018	19%	0.185	C	C	.	.	S	Bend	trans	-79.2	108.9	-175.7	-179.6	0	0	0	0	109.6	L153 R156 C202 L216 V219	L153-V206 HydrophobicContact CD2-CB 4.4Å; L153-V206 HydrophobicContact CD2-CG1 4.17Å; L153-V206 HydrophobicContact CD2-CG2 4.09Å; R156-V206 HydrophobicContact CG-CG1 4.24Å; R156-V206 PolarHBondContact NH1-O 2.86Å; C202-V206 HydrophobicContact CB-CG2 4.02Å; C202-V206 VanDerWaalsContact O-CB 3.3Å; C202-V206 WeakPolarHBondContact O-CB 3.23Å; C202-V206 PolarHBondContact O-N 3.48Å; V206-L216 HydrophobicContact CG1-CD1 3.76Å; V206-V219 HydrophobicContact CG2-CG1 3.97Å
207	S	97.9	Very high	98.1	Very high	62 Å²	62	36 Å²	36	43%	0.434	19%	0.194	S	C	.	.			trans	-64.2	145	175.9	-179.8	0	0	0	0	111.7	V205 E209 V210	V205-S207 PolarHBondContact O-N 2.84Å; S207-E209 PolarHBondContact O-N 3.39Å; S207-E209 PolarHBondContact OG-N 3.23Å; S207-E209 VanDerWaalsContact OG-N 3.13Å; S207-V210 WeakPolarHBondContact O-CG2 3.34Å
208	S	97.3	Very high	98.1	Very high	46 Å²	46	35.9 Å²	35.9	32%	0.322	19%	0.194	S	C	.	.	T	Hydrogen-bonded Turn	trans	-66.5	-21.6	170.2	54.5	0	0	0	0	112.8	R156 Y158 V210	R156-S208 VanDerWaalsContact O-CA 3.29Å; R156-S208 WeakPolarHBondContact O-CA 3.32Å; R156-S208 WeakPolarHBondContact O-CB 3.15Å; Y158-S208 VanDerWaalsContact CD1-O 3.31Å; Y158-S208 WeakPolarHBondContact CD1-O 3.19Å; Y158-S208 WeakPolarHBondContact CE1-O 3.43Å; S208-V210 VanDerWaalsContact C-N 3.33Å; S208-V210 PolarHBondContact O-N 3.39Å
209	E	97.6	Very high	98.1	Very high	88 Å²	88	36.5 Å²	36.5	41%	0.411	20%	0.198	S	C	.	.	T	Hydrogen-bonded Turn	trans	-84.6	-1.5	-174.7	-61.2	-51.8	126.1	0	0	114.5	Y158 R159 S207 A211	Y158-E209 WeakPolarHBondContact CE1-OE1 3.43Å; Y158-E209 VanDerWaalsContact OH-CD 3.22Å; Y158-E209 PolarHBondContact OH-OE1 2.96Å; Y158-E209 PolarHBondContact OH-OE2 3.28Å; R159-E209 WeakPolarHBondContact CD-O 3.45Å; R159-E209 PolarHBondContact NH1-O 2.89Å; S207-E209 PolarHBondContact O-N 3.39Å; S207-E209 PolarHBondContact OG-N 3.23Å; S207-E209 VanDerWaalsContact OG-N 3.13Å; E209-A211 PolarHBondContact O-N 3.21Å
210	V	97.5	Very high	98.1	Very high	4 Å²	4	36.1 Å²	36.1	2%	0.024	20%	0.196	C	C	.	.			trans	-53.6	125.6	176.6	172.4	0	0	0	0	110	L160 S207 S208 E215 L216	L160-V210 HydrophobicContact CD1-CG1 4.42Å; S207-V210 WeakPolarHBondContact O-CG2 3.34Å; S208-V210 VanDerWaalsContact C-N 3.33Å; S208-V210 PolarHBondContact O-N 3.39Å; V210-E215 HydrophobicContact CG1-CB 4.13Å; V210-E215 HydrophobicContact CG1-CG 4.06Å; V210-L216 HydrophobicContact CG1-CB 3.85Å
211	A	94.8	Very high	98.1	Very high	39 Å²	39	36.3 Å²	36.3	32%	0.322	20%	0.197	S	C	.	.			trans	-106.5	-18.3	-166.8	0	0	0	0	0	113.7	R159 L160 E209 E215	R159-A211 VanDerWaalsContact CZ-CB 3.48Å; L160-A211 WeakPolarHBondContact CD2-O 3.48Å; E209-A211 PolarHBondContact O-N 3.21Å; A211-E215 PolarHBondContact N-OE2 2.9Å
212	T	97.8	Very high	98.1	Very high	70 Å²	70	36.3 Å²	36.3	43%	0.429	20%	0.197	S	C	.	.			trans	-130.4	149.8	-178.6	70.4	0	0	0	0	112.2	L160 H214 E215 L216	L160-T212 VanDerWaalsContact CD2-C 3.4Å; T212-H214 PolarHBondContact O-N 2.97Å; T212-E215 PolarHBondContact O-N 3.02Å; T212-E215 WeakPolarHBondContact OG1-CB 3.29Å; T212-E215 PolarHBondContact OG1-N 3.49Å; T212-E215 VanDerWaalsContact OG1-N 3.12Å; T212-L216 PolarHBondContact O-N 3.36Å; T212-L216 VanDerWaalsContact O-N 3.08Å
213	E	97.8	Very high	98.1	Very high	76 Å²	76	36.3 Å²	36.3	36%	0.355	20%	0.197	S	C	.	.	H	α-helix	trans	-63.4	-34.1	175.3	-68.1	176.8	-161.4	0	0	111.8	L163 L216 Q217	L163-E213 HydrophobicContact CD1-CG 4.26Å; E213-L216 PolarHBondContact O-N 2.92Å; E213-Q217 VanDerWaalsContact O-CB 3.32Å; E213-Q217 WeakPolarHBondContact O-CB 3.46Å; E213-Q217 PolarHBondContact O-N 3.35Å
214	H	97.9	Very high	98.2	Very high	97 Å²	97	34.6 Å²	34.6	45%	0.449	19%	0.191	S	C	.	.	H	α-helix	trans	-64	-44.6	176.8	-179.5	-92.4	0	0	0	111.9	T212 Q217 A218 V244	T212-H214 PolarHBondContact O-N 2.97Å; H214-Q217 PolarHBondContact O-N 2.95Å; H214-A218 WeakPolarHBondContact O-CB 3.33Å; H214-A218 PolarHBondContact O-N 2.87Å; H214-V244 PolarHBondContact NE2-O 3.24Å
215	E	98.2	Very high	98.2	Very high	81 Å²	81	33.1 Å²	33.1	38%	0.379	18%	0.18	S	C	.	.	H	α-helix	trans	-62.6	-44.4	174.3	-178.2	-172.8	-176.2	0	0	111.3	V210 A211 T212 Q217 A218 V219	V210-E215 HydrophobicContact CG1-CB 4.13Å; V210-E215 HydrophobicContact CG1-CG 4.06Å; A211-E215 PolarHBondContact N-OE2 2.9Å; T212-E215 PolarHBondContact O-N 3.02Å; T212-E215 WeakPolarHBondContact OG1-CB 3.29Å; T212-E215 PolarHBondContact OG1-N 3.49Å; T212-E215 VanDerWaalsContact OG1-N 3.12Å; E215-Q217 PolarHBondContact O-N 3.19Å; E215-A218 WeakPolarHBondContact O-CB 3.47Å; E215-A218 PolarHBondContact O-N 3.46Å; E215-V219 WeakPolarHBondContact O-CG2 3.43Å; E215-V219 PolarHBondContact O-N 3.21Å
216	L	98.7	Very high	98.2	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-59.2	-47.3	175.2	177.7	59	0	0	0	111.5	L153 L160 L163 W171 V206 V210 T212 E213 A218 V219 L220	L153-L216 HydrophobicContact CD2-CD1 4.25Å; L160-L216 HydrophobicContact CD1-CB 4.03Å; L160-L216 HydrophobicContact CD1-CD2 3.65Å; L160-L216 HydrophobicContact CD1-CG 4.46Å; L163-L216 HydrophobicContact CD1-CD2 4.15Å; L163-L216 HydrophobicContact CD2-CD2 3.38Å; L163-L216 HydrophobicContact CG-CD2 4.44Å; W171-L216 HydrophobicContact CZ3-CD2 4.3Å; W171-L216 HydrophobicContact CZ3-CG 4.22Å; V206-L216 HydrophobicContact CG1-CD1 3.76Å; V210-L216 HydrophobicContact CG1-CB 3.85Å; T212-L216 PolarHBondContact O-N 3.36Å; T212-L216 VanDerWaalsContact O-N 3.08Å; E213-L216 PolarHBondContact O-N 2.92Å; L216-A218 VanDerWaalsContact C-N 3.3Å; L216-A218 PolarHBondContact O-N 3.33Å; L216-V219 PolarHBondContact O-N 3.48Å; L216-L220 VanDerWaalsContact O-CB 3.3Å; L216-L220 WeakPolarHBondContact O-CB 3.22Å; L216-L220 PolarHBondContact O-N 3.37Å
217	Q	98.6	Very high	98.2	Very high	44 Å²	44	32 Å²	32	21%	0.206	17%	0.173	C	C	.	.	H	α-helix	trans	-59.6	-43.3	178.2	-173.6	-180	33.5	0	0	110.6	W171 E213 H214 E215 L220 L221 V244	W171-Q217 VanDerWaalsContact CD1-NE2 3.25Å; W171-Q217 HydrophobicContact CD2-CB 4.15Å; W171-Q217 HydrophobicContact CD2-CG 3.73Å; W171-Q217 HydrophobicContact CE3-CB 3.86Å; W171-Q217 HydrophobicContact CE3-CG 3.81Å; W171-Q217 HydrophobicContact CG-CG 4.07Å; W171-Q217 HydrophobicContact CH2-CB 4.07Å; W171-Q217 HydrophobicContact CZ2-CB 4.32Å; W171-Q217 HydrophobicContact CZ3-CB 3.83Å; W171-Q217 HydrophobicContact CZ3-CG 4.3Å; E213-Q217 VanDerWaalsContact O-CB 3.32Å; E213-Q217 WeakPolarHBondContact O-CB 3.46Å; E213-Q217 PolarHBondContact O-N 3.35Å; H214-Q217 PolarHBondContact O-N 2.95Å; E215-Q217 PolarHBondContact O-N 3.19Å; Q217-L220 PolarHBondContact O-N 3.26Å; Q217-L221 HydrophobicContact CG-CD1 3.9Å; Q217-L221 HydrophobicContact CG-CG 4.25Å; Q217-L221 VanDerWaalsContact O-CB 3.29Å; Q217-L221 WeakPolarHBondContact O-CB 3.34Å; Q217-L221 VanDerWaalsContact O-CG 3.23Å; Q217-L221 WeakPolarHBondContact O-CG 3.34Å; Q217-L221 PolarHBondContact O-N 3.49Å; Q217-V244 HydrophobicContact CG-CG1 4.31Å; Q217-V244 HydrophobicContact CG-CG2 4.28Å
218	A	98.7	Very high	98.3	Very high	1 Å²	1	29 Å²	29	1%	0.008	15%	0.153	C	C	.	.	H	α-helix	trans	-59.9	-49.8	177	0	0	0	0	0	112	H214 E215 L216 L221 T222 V244 E245 R254	H214-A218 WeakPolarHBondContact O-CB 3.33Å; H214-A218 PolarHBondContact O-N 2.87Å; E215-A218 WeakPolarHBondContact O-CB 3.47Å; E215-A218 PolarHBondContact O-N 3.46Å; L216-A218 VanDerWaalsContact C-N 3.3Å; L216-A218 PolarHBondContact O-N 3.33Å; A218-L221 PolarHBondContact O-N 3.31Å; A218-T222 PolarHBondContact O-N 3.47Å; A218-T222 PolarHBondContact O-OG1 3.46Å; A218-V244 HydrophobicContact CB-CG2 3.86Å; A218-E245 HydrophobicContact CB-CG 3.67Å; A218-R254 PolarHBondContact O-NH1 3.38Å
219	V	98.8	Very high	98.3	Very high	15 Å²	15	30 Å²	30	9%	0.091	16%	0.159	C	C	.	.	H	α-helix	trans	-64.8	-43.6	179.3	178.4	0	0	0	0	111.5	V205 V206 E215 L216 T222 C223	V205-V219 HydrophobicContact CG1-CG1 3.82Å; V206-V219 HydrophobicContact CG2-CG1 3.97Å; E215-V219 WeakPolarHBondContact O-CG2 3.43Å; E215-V219 PolarHBondContact O-N 3.21Å; L216-V219 PolarHBondContact O-N 3.48Å; V219-T222 PolarHBondContact O-N 3.42Å; V219-C223 PolarHBondContact O-N 3.42Å; V219-C223 PolarHBondContact O-SG 3.09Å
220	L	98.9	Very high	98.4	Very high	0 Å²	0	30.5 Å²	30.5	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-62.6	-43.8	178.1	179.2	62.9	0	0	0	111.5	L153 P168 W171 L172 V198 C202 L216 Q217 T222 C223 L224	L153-L220 HydrophobicContact CD1-CD1 4.18Å; L153-L220 HydrophobicContact CD1-CD2 4Å; P168-L220 HydrophobicContact CB-CD2 3.84Å; W171-L220 HydrophobicContact CE3-CD2 3.99Å; L172-L220 HydrophobicContact CD2-CD1 4.28Å; L172-L220 HydrophobicContact CD2-CD2 4.1Å; L172-L220 HydrophobicContact CD2-CG 4.05Å; L172-L220 HydrophobicContact CG-CD2 4.28Å; V198-L220 HydrophobicContact CG1-CD1 4.33Å; C202-L220 WeakPolarHBondContact SG-CD1 3.37Å; L216-L220 VanDerWaalsContact O-CB 3.3Å; L216-L220 WeakPolarHBondContact O-CB 3.22Å; L216-L220 PolarHBondContact O-N 3.37Å; Q217-L220 PolarHBondContact O-N 3.26Å; L220-T222 VanDerWaalsContact C-N 3.33Å; L220-C223 WeakPolarHBondContact O-CB 3.31Å; L220-C223 PolarHBondContact O-N 2.89Å; L220-L224 WeakPolarHBondContact O-CB 3.32Å; L220-L224 PolarHBondContact O-N 3.02Å
221	L	98.9	Very high	98.4	Very high	4 Å²	4	31.7 Å²	31.7	2%	0.021	16%	0.164	C	C	.	.	H	α-helix	trans	-70.7	-28.4	178.8	-69.5	-177.1	0	0	0	112.6	V175 Q217 A218 L224 Y225 F242 V244	V175-L221 HydrophobicContact CG2-CD2 3.82Å; Q217-L221 HydrophobicContact CG-CD1 3.9Å; Q217-L221 HydrophobicContact CG-CG 4.25Å; Q217-L221 VanDerWaalsContact O-CB 3.29Å; Q217-L221 WeakPolarHBondContact O-CB 3.34Å; Q217-L221 VanDerWaalsContact O-CG 3.23Å; Q217-L221 WeakPolarHBondContact O-CG 3.34Å; Q217-L221 PolarHBondContact O-N 3.49Å; A218-L221 PolarHBondContact O-N 3.31Å; L221-L224 HydrophobicContact CD2-CD2 3.94Å; L221-L224 PolarHBondContact O-N 2.98Å; L221-Y225 WeakPolarHBondContact O-CB 3.38Å; L221-Y225 PolarHBondContact O-N 3.48Å; L221-F242 WeakPolarHBondContact CB-O 3.25Å; L221-V244 HydrophobicContact CD1-CG1 3.59Å; L221-V244 HydrophobicContact CD1-CG2 4.39Å
222	T	98.9	Very high	98.6	Very high	0 Å²	0	30.8 Å²	30.8	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-64.9	-45.3	167.4	-53.5	0	0	0	0	111.2	A218 V219 L220 L224 Y225 L226 F251 R254 C255 I258	A218-T222 PolarHBondContact O-N 3.47Å; A218-T222 PolarHBondContact O-OG1 3.46Å; V219-T222 PolarHBondContact O-N 3.42Å; L220-T222 VanDerWaalsContact C-N 3.33Å; T222-L224 VanDerWaalsContact C-N 3.3Å; T222-L224 PolarHBondContact O-N 3.34Å; T222-Y225 PolarHBondContact O-N 3.28Å; T222-L226 WeakPolarHBondContact O-CG 3.43Å; T222-L226 PolarHBondContact O-N 3.15Å; T222-L226 VanDerWaalsContact O-N 3.08Å; T222-F251 HydrophobicContact CG2-CE2 4.31Å; T222-F251 WeakPolarHBondContact OG1-CD2 3.49Å; T222-R254 HydrophobicContact CG2-CB 4.18Å; T222-R254 HydrophobicContact CG2-CG 4.06Å; T222-R254 PolarHBondContact OG1-NH1 2.95Å; T222-C255 VanDerWaalsContact CG2-SG 3.55Å; T222-I258 HydrophobicContact CG2-CD1 3.71Å
223	C	98.9	Very high	98.5	Very high	0 Å²	0	31.3 Å²	31.3	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-60.5	-41.6	174.6	-64.4	0	0	0	0	111.5	L201 V219 L220 L226 S227	L201-C223 HydrophobicContact CB-CB 4.12Å; L201-C223 HydrophobicContact CD1-CB 4.21Å; L201-C223 WeakPolarHBondContact CD1-O 3.42Å; V219-C223 PolarHBondContact O-N 3.42Å; V219-C223 PolarHBondContact O-SG 3.09Å; L220-C223 WeakPolarHBondContact O-CB 3.31Å; L220-C223 PolarHBondContact O-N 2.89Å; C223-L226 PolarHBondContact O-N 3.33Å; C223-S227 WeakPolarHBondContact O-CB 3.48Å; C223-S227 PolarHBondContact O-N 2.91Å; C223-S227 PolarHBondContact O-OG 2.74Å
224	L	98.9	Very high	98.5	Very high	0 Å²	0	30.4 Å²	30.4	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-62.8	-48.2	176.5	-172.8	64.3	0	0	0	110.9	L172 V175 F189 I190 V198 L220 L221 T222 L226 S227 Y228 F242	L172-L224 HydrophobicContact CD2-CB 4.13Å; L172-L224 HydrophobicContact CD2-CD1 3.82Å; L172-L224 HydrophobicContact CD2-CD2 3.61Å; L172-L224 HydrophobicContact CD2-CG 4.01Å; V175-L224 HydrophobicContact CB-CD2 4.01Å; V175-L224 HydrophobicContact CG1-CD2 3.96Å; V175-L224 HydrophobicContact CG2-CD2 4.36Å; F189-L224 HydrophobicContact CD1-CD1 4.45Å; F189-L224 HydrophobicContact CE1-CD1 4.18Å; I190-L224 HydrophobicContact CD1-CD1 4.27Å; V198-L224 HydrophobicContact CG2-CD1 3.98Å; L220-L224 WeakPolarHBondContact O-CB 3.32Å; L220-L224 PolarHBondContact O-N 3.02Å; L221-L224 HydrophobicContact CD2-CD2 3.94Å; L221-L224 PolarHBondContact O-N 2.98Å; T222-L224 VanDerWaalsContact C-N 3.3Å; T222-L224 PolarHBondContact O-N 3.34Å; L224-L226 VanDerWaalsContact C-N 3.31Å; L224-L226 PolarHBondContact O-N 3.3Å; L224-S227 CarbonylContact O-C 3.57Å; L224-S227 WeakPolarHBondContact O-CA 3.41Å; L224-S227 VanDerWaalsContact O-CB 3.3Å; L224-S227 WeakPolarHBondContact O-CB 3.49Å; L224-S227 PolarHBondContact O-N 3.15Å; L224-Y228 HydrophobicContact CD1-CD2 3.99Å; L224-Y228 HydrophobicContact CD1-CE2 3.65Å; L224-Y228 HydrophobicContact CD2-CD2 4.49Å; L224-Y228 HydrophobicContact CD2-CE2 3.91Å; L224-Y228 HydrophobicContact CG-CD2 3.78Å; L224-Y228 HydrophobicContact CG-CE2 3.59Å; L224-Y228 WeakPolarHBondContact O-CD2 3.34Å; L224-Y228 PolarHBondContact O-N 2.84Å; L224-F242 HydrophobicContact CB-CD1 4.45Å; L224-F242 HydrophobicContact CB-CE1 4.42Å; L224-F242 HydrophobicContact CD2-CD1 4.26Å; L224-F242 HydrophobicContact CD2-CE1 3.95Å; L224-F242 HydrophobicContact CG-CD1 4.4Å; L224-F242 HydrophobicContact CG-CE1 3.96Å
225	Y	98.9	Very high	98.5	Very high	34 Å²	34	34.2 Å²	34.2	13%	0.133	18%	0.176	C	C	.	.	H	α-helix	trans	-56.1	-44.1	178.3	175.6	-104.9	0	0	0	112.6	L221 T222 S227 Y228 S229 F242 F251 W252	L221-Y225 WeakPolarHBondContact O-CB 3.38Å; L221-Y225 PolarHBondContact O-N 3.48Å; T222-Y225 PolarHBondContact O-N 3.28Å; Y225-S227 VanDerWaalsContact C-N 3.32Å; Y225-Y228 PolarHBondContact O-N 3Å; Y225-S229 WeakPolarHBondContact O-CB 3.46Å; Y225-S229 PolarHBondContact O-N 3.22Å; Y225-S229 PolarHBondContact O-OG 3.08Å; Y225-F242 HydrophobicContact CD2-CB 4.43Å; Y225-F242 HydrophobicContact CD2-CD1 4.33Å; Y225-F242 AromaticContact CD2-CD2 3.65Å; Y225-F242 HydrophobicContact CD2-CD2 3.65Å; Y225-F242 AromaticContact CD2-CE2 3.88Å; Y225-F242 HydrophobicContact CD2-CE2 3.88Å; Y225-F242 AromaticContact CD2-CG 3.89Å; Y225-F242 HydrophobicContact CD2-CG 3.89Å; Y225-F242 HydrophobicContact CD2-CZ 4.3Å; Y225-F242 HydrophobicContact CE2-CD2 4.46Å; Y225-F242 HydrophobicContact CG-CD2 4.5Å; Y225-F242 HydrophobicContact CG-CG 4.3Å; Y225-F251 AromaticContact CD1-CE1 3.88Å; Y225-F251 HydrophobicContact CD1-CE1 3.88Å; Y225-F251 AromaticContact CD1-CZ 3.66Å; Y225-F251 HydrophobicContact CD1-CZ 3.66Å; Y225-F251 HydrophobicContact CD2-CZ 4.43Å; Y225-F251 HydrophobicContact CE1-CE1 4.14Å; Y225-F251 HydrophobicContact CE1-CZ 4.34Å; Y225-F251 HydrophobicContact CG-CE1 4.32Å; Y225-F251 AromaticContact CG-CZ 3.71Å; Y225-F251 HydrophobicContact CG-CZ 3.71Å; Y225-W252 HydrophobicContact CE1-CH2 4.13Å; Y225-W252 AromaticContact CE1-CZ3 3.77Å; Y225-W252 HydrophobicContact CE1-CZ3 3.77Å
226	L	98.9	Very high	98.5	Very high	11 Å²	11	33.7 Å²	33.7	6%	0.058	18%	0.181	C	C	.	.	H	α-helix	trans	-65.9	-35.8	174.8	-68.3	177.2	0	0	0	112	T222 C223 L224 S229 Y230 C255 I258 I259	T222-L226 WeakPolarHBondContact O-CG 3.43Å; T222-L226 PolarHBondContact O-N 3.15Å; T222-L226 VanDerWaalsContact O-N 3.08Å; C223-L226 PolarHBondContact O-N 3.33Å; L224-L226 VanDerWaalsContact C-N 3.31Å; L224-L226 PolarHBondContact O-N 3.3Å; L226-S229 PolarHBondContact O-N 3.42Å; L226-Y230 VanDerWaalsContact O-CB 3.29Å; L226-Y230 WeakPolarHBondContact O-CB 3.44Å; L226-Y230 PolarHBondContact O-N 2.95Å; L226-C255 HydrophobicContact CD2-CB 4.29Å; L226-I258 HydrophobicContact CD1-CB 3.61Å; L226-I258 HydrophobicContact CD1-CD1 4.12Å; L226-I258 HydrophobicContact CD1-CG1 4.48Å; L226-I258 HydrophobicContact CD1-CG2 3.41Å; L226-I258 VanDerWaalsContact CD1-CG2 3.41Å; L226-I259 HydrophobicContact CD1-CG1 4.27Å; L226-I259 HydrophobicContact CD2-CD1 3.87Å; L226-I259 HydrophobicContact CD2-CG1 3.97Å
227	S	98.9	Very high	98.5	Very high	0 Å²	0	34.5 Å²	34.5	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-64.9	-43.1	175	-54	0	0	0	0	111.8	F189 V198 L201 C223 L224 Y225 S229 Y230 M231	F189-S227 VanDerWaalsContact CZ-C 3.5Å; F189-S227 WeakPolarHBondContact CZ-O 3.33Å; V198-S227 WeakPolarHBondContact CG2-OG 3.34Å; L201-S227 WeakPolarHBondContact CD1-OG 3.29Å; C223-S227 WeakPolarHBondContact O-CB 3.48Å; C223-S227 PolarHBondContact O-N 2.91Å; C223-S227 PolarHBondContact O-OG 2.74Å; L224-S227 CarbonylContact O-C 3.57Å; L224-S227 WeakPolarHBondContact O-CA 3.41Å; L224-S227 VanDerWaalsContact O-CB 3.3Å; L224-S227 WeakPolarHBondContact O-CB 3.49Å; L224-S227 PolarHBondContact O-N 3.15Å; Y225-S227 VanDerWaalsContact C-N 3.32Å; S227-S229 VanDerWaalsContact C-N 3.33Å; S227-Y230 PolarHBondContact O-N 3.43Å; S227-M231 WeakPolarHBondContact O-CA 3.5Å; S227-M231 WeakPolarHBondContact O-CB 3.5Å; S227-M231 PolarHBondContact O-N 2.93Å
228	Y	98.8	Very high	98.5	Very high	0 Å²	0	33.5 Å²	33.5	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-61.1	-43.9	171.8	-87.5	-89.7	0	0	0	111.2	V175 D176 L179 F189 L224 Y225 Y230 G232 Y237 F242	V175-Y228 HydrophobicContact CG1-CE2 4.42Å; D176-Y228 VanDerWaalsContact CA-OH 3.24Å; D176-Y228 WeakPolarHBondContact CA-OH 3.45Å; D176-Y228 WeakPolarHBondContact CB-OH 3.18Å; D176-Y228 VanDerWaalsContact CG-OH 3.24Å; D176-Y228 PolarHBondContact OD1-OH 2.86Å; L179-Y228 HydrophobicContact CD1-CD1 4.01Å; L179-Y228 HydrophobicContact CD1-CE1 3.44Å; L179-Y228 VanDerWaalsContact CD1-CE1 3.44Å; L179-Y228 HydrophobicContact CD1-CE2 4.38Å; F189-Y228 HydrophobicContact CB-CD1 3.89Å; F189-Y228 HydrophobicContact CB-CE1 3.16Å; F189-Y228 HydrophobicContact CB-CE2 4.29Å; F189-Y228 WeakPolarHBondContact CB-OH 3.42Å; F189-Y228 HydrophobicContact CD1-CD1 4.23Å; F189-Y228 AromaticContact CD1-CD2 3.9Å; F189-Y228 HydrophobicContact CD1-CD2 3.9Å; F189-Y228 AromaticContact CD1-CE1 3.91Å; F189-Y228 HydrophobicContact CD1-CE1 3.91Å; F189-Y228 AromaticContact CD1-CE2 3.54Å; F189-Y228 HydrophobicContact CD1-CE2 3.54Å; F189-Y228 HydrophobicContact CD1-CG 4.24Å; F189-Y228 AromaticContact CD1-CZ 3.54Å; F189-Y228 AromaticContact CD2-CD1 3.94Å; F189-Y228 HydrophobicContact CD2-CD1 3.94Å; F189-Y228 HydrophobicContact CD2-CE1 4.1Å; F189-Y228 HydrophobicContact CD2-CG 4.31Å; F189-Y228 HydrophobicContact CE1-CD2 4.1Å; F189-Y228 HydrophobicContact CE1-CE2 4.11Å; F189-Y228 HydrophobicContact CE1-CG 4.48Å; F189-Y228 AromaticContact CG-CD1 3.76Å; F189-Y228 HydrophobicContact CG-CD1 3.76Å; F189-Y228 HydrophobicContact CG-CD2 4.27Å; F189-Y228 AromaticContact CG-CE1 3.47Å; F189-Y228 HydrophobicContact CG-CE1 3.47Å; F189-Y228 VanDerWaalsContact CG-CE1 3.47Å; F189-Y228 HydrophobicContact CG-CE2 4.01Å; F189-Y228 HydrophobicContact CG-CG 4.16Å; F189-Y228 AromaticContact CG-CZ 3.59Å; L224-Y228 HydrophobicContact CD1-CD2 3.99Å; L224-Y228 HydrophobicContact CD1-CE2 3.65Å; L224-Y228 HydrophobicContact CD2-CD2 4.49Å; L224-Y228 HydrophobicContact CD2-CE2 3.91Å; L224-Y228 HydrophobicContact CG-CD2 3.78Å; L224-Y228 HydrophobicContact CG-CE2 3.59Å; L224-Y228 WeakPolarHBondContact O-CD2 3.34Å; L224-Y228 PolarHBondContact O-N 2.84Å; Y225-Y228 PolarHBondContact O-N 3Å; Y228-Y230 VanDerWaalsContact C-N 3.29Å; Y228-Y230 PolarHBondContact O-N 3.17Å; Y228-G232 WeakPolarHBondContact O-CA 3.4Å; Y228-G232 PolarHBondContact O-N 3.24Å; Y228-Y237 AromaticContact CD1-CD1 3.71Å; Y228-Y237 HydrophobicContact CD1-CD1 3.71Å; Y228-Y237 HydrophobicContact CD1-CD2 4.28Å; Y228-Y237 AromaticContact CD1-CE1 3.5Å; Y228-Y237 HydrophobicContact CD1-CE1 3.5Å; Y228-Y237 HydrophobicContact CD1-CE2 4.11Å; Y228-Y237 HydrophobicContact CD1-CG 4.08Å; Y228-Y237 AromaticContact CD1-CZ 3.7Å; Y228-Y237 HydrophobicContact CE1-CD1 4.39Å; Y228-Y237 HydrophobicContact CE1-CE1 4.1Å; Y228-Y237 HydrophobicContact CG-CD1 4.45Å; Y228-Y237 HydrophobicContact CG-CD2 4.48Å; Y228-Y237 HydrophobicContact CG-CG 4.41Å; Y228-Y237 WeakPolarHBondContact O-CE2 3.2Å; Y228-F242 AromaticContact CD2-CE1 3.58Å; Y228-F242 HydrophobicContact CD2-CE1 3.58Å; Y228-F242 AromaticContact CD2-CZ 3.66Å; Y228-F242 HydrophobicContact CD2-CZ 3.66Å; Y228-F242 AromaticContact CE2-CE1 3.88Å; Y228-F242 HydrophobicContact CE2-CE1 3.88Å; Y228-F242 HydrophobicContact CE2-CZ 4.02Å; Y228-F242 HydrophobicContact CG-CE1 4.32Å; Y228-F242 AromaticContact CG-CZ 3.98Å; Y228-F242 HydrophobicContact CG-CZ 3.98Å
229	S	98.7	Very high	98.4	Very high	65 Å²	65	35.1 Å²	35.1	46%	0.455	19%	0.19	S	C	.	.	H	α-helix	trans	-68.3	-28.2	-177.8	-59	0	0	0	0	113	Y225 L226 S227	Y225-S229 WeakPolarHBondContact O-CB 3.46Å; Y225-S229 PolarHBondContact O-N 3.22Å; Y225-S229 PolarHBondContact O-OG 3.08Å; L226-S229 PolarHBondContact O-N 3.42Å; S227-S229 VanDerWaalsContact C-N 3.33Å
230	Y	98.8	Very high	98.4	Very high	99 Å²	99	43.1 Å²	43.1	39%	0.388	22%	0.224	S	C	.	.	H	α-helix	trans	-96.3	-44.8	-178.1	-167.5	-88.5	0	0	0	113.6	F197 L226 S227 Y228 M266 L267	F197-Y230 AromaticContact CE2-CD1 3.89Å; F197-Y230 HydrophobicContact CE2-CD1 3.89Å; F197-Y230 HydrophobicContact CE2-CE1 4.15Å; F197-Y230 AromaticContact CZ-CD1 3.6Å; F197-Y230 HydrophobicContact CZ-CD1 3.6Å; F197-Y230 HydrophobicContact CZ-CE1 4.2Å; F197-Y230 HydrophobicContact CZ-CG 4.13Å; L226-Y230 VanDerWaalsContact O-CB 3.29Å; L226-Y230 WeakPolarHBondContact O-CB 3.44Å; L226-Y230 PolarHBondContact O-N 2.95Å; S227-Y230 PolarHBondContact O-N 3.43Å; Y228-Y230 VanDerWaalsContact C-N 3.29Å; Y228-Y230 PolarHBondContact O-N 3.17Å; Y230-M266 HydrophobicContact CD1-CE 4.31Å; Y230-M266 HydrophobicContact CD2-CE 3.53Å; Y230-M266 HydrophobicContact CE1-CB 4.34Å; Y230-M266 HydrophobicContact CE2-CB 4.37Å; Y230-M266 HydrophobicContact CE2-CE 4.21Å; Y230-M266 HydrophobicContact CG-CE 3.58Å; Y230-L267 WeakPolarHBondContact OH-CA 3.34Å
231	M	98.4	Very high	98.3	Very high	30 Å²	30	44.3 Å²	44.3	15%	0.148	23%	0.232	C	C	.	.	H	α-helix	trans	-104.5	-6.9	-174.5	-62.5	-66.4	-70.4	0	0	113.3	F189 F197 S227 N270	F189-M231 HydrophobicContact CE2-CB 3.88Å; F189-M231 HydrophobicContact CZ-CB 4.21Å; F197-M231 HydrophobicContact CD1-CG 4Å; F197-M231 HydrophobicContact CD2-CE 4.41Å; F197-M231 HydrophobicContact CD2-CG 3.74Å; F197-M231 HydrophobicContact CD2-SD 3.87Å; F197-M231 HydrophobicContact CE1-CG 4.04Å; F197-M231 HydrophobicContact CE2-CG 3.8Å; F197-M231 HydrophobicContact CE2-SD 3.83Å; F197-M231 HydrophobicContact CG-CG 3.84Å; F197-M231 HydrophobicContact CZ-CG 3.94Å; F197-M231 HydrophobicContact CZ-SD 4.44Å; S227-M231 WeakPolarHBondContact O-CA 3.5Å; S227-M231 WeakPolarHBondContact O-CB 3.5Å; S227-M231 PolarHBondContact O-N 2.93Å; M231-N270 WeakPolarHBondContact CE-OD1 3.48Å; M231-N270 PolarHBondContact SD-ND2 2.91Å; M231-N270 VanDerWaalsContact SD-ND2 3.41Å
232	G	97.4	Very high	98.3	Very high	20 Å²	20	44.2 Å²	44.2	21%	0.206	23%	0.231	C	C	.	.			trans	-73	151.4	-179.9	0	0	0	0	0	112.4	Y228 Y237	Y228-G232 WeakPolarHBondContact O-CA 3.4Å; Y228-G232 PolarHBondContact O-N 3.24Å; G232-Y237 VanDerWaalsContact CA-OH 3.31Å; G232-Y237 WeakPolarHBondContact CA-OH 3.21Å
233	N	96.5	Very high	98.3	Very high	80 Å²	80	46.1 Å²	46.1	43%	0.428	24%	0.241	S	C	.	.	S	Bend	trans	-82.5	-20.6	179.6	-64.2	-29.5	0	0	0	112.6	Y237	N233-Y237 PolarHBondContact N-OH 3.29Å
234	E	97.7	Very high	98.2	Very high	58 Å²	58	48.3 Å²	48.3	27%	0.271	25%	0.254	S	S	.	.	S	Bend	trans	-84.4	145.5	-178.3	-50.3	-60.1	149	0	0	110.2	W184 Q185 S236 Y237	W184-E234 WeakPolarHBondContact O-CG 3.31Å; Q185-E234 HydrophobicContact CB-CG 3.96Å; E234-S236 PolarHBondContact O-N 3.43Å; E234-S236 VanDerWaalsContact O-N 3.12Å; E234-Y237 HydrophobicContact CB-CE1 3.91Å; E234-Y237 HydrophobicContact CB-CE2 4.02Å; E234-Y237 HydrophobicContact CG-CE1 3.85Å; E234-Y237 WeakPolarHBondContact CG-OH 3.47Å; E234-Y237 PolarHBondContact N-OH 3.32Å
235	I	97.6	Very high	98.1	Very high	177 Å²	177	50 Å²	50	91%	0.908	26%	0.262	S	S	*	.	S	Bend	trans	-64.6	-18.8	-178.2	61.7	170.3	0	0	0	113.8
236	S	98.1	Very high	97.8	Very high	70 Å²	70	54.8 Å²	54.8	49%	0.49	30%	0.3	S	S	.	.			trans	-163	151.4	-179.7	65.6	0	0	0	0	111.5	E234	E234-S236 PolarHBondContact O-N 3.43Å; E234-S236 VanDerWaalsContact O-N 3.12Å
237	Y	98.6	Very high	97.7	Very high	16 Å²	16	56.5 Å²	56.5	6%	0.063	31%	0.313	C	S	.	.			trans	-125.2	142.4	173.8	-64.5	-85.1	0	0	0	110.9	L179 Q185 Y228 G232 N233 E234	L179-Y237 HydrophobicContact CD1-CD1 4.14Å; Q185-Y237 HydrophobicContact CB-CE1 4.49Å; Y228-Y237 AromaticContact CD1-CD1 3.71Å; Y228-Y237 HydrophobicContact CD1-CD1 3.71Å; Y228-Y237 HydrophobicContact CD1-CD2 4.28Å; Y228-Y237 AromaticContact CD1-CE1 3.5Å; Y228-Y237 HydrophobicContact CD1-CE1 3.5Å; Y228-Y237 HydrophobicContact CD1-CE2 4.11Å; Y228-Y237 HydrophobicContact CD1-CG 4.08Å; Y228-Y237 AromaticContact CD1-CZ 3.7Å; Y228-Y237 HydrophobicContact CE1-CD1 4.39Å; Y228-Y237 HydrophobicContact CE1-CE1 4.1Å; Y228-Y237 HydrophobicContact CG-CD1 4.45Å; Y228-Y237 HydrophobicContact CG-CD2 4.48Å; Y228-Y237 HydrophobicContact CG-CG 4.41Å; Y228-Y237 WeakPolarHBondContact O-CE2 3.2Å; G232-Y237 VanDerWaalsContact CA-OH 3.31Å; G232-Y237 WeakPolarHBondContact CA-OH 3.21Å; N233-Y237 PolarHBondContact N-OH 3.29Å; E234-Y237 HydrophobicContact CB-CE1 3.91Å; E234-Y237 HydrophobicContact CB-CE2 4.02Å; E234-Y237 HydrophobicContact CG-CE1 3.85Å; E234-Y237 WeakPolarHBondContact CG-OH 3.47Å; E234-Y237 PolarHBondContact N-OH 3.32Å
238	P	98.3	Very high	97.6	Very high	23 Å²	23	62.6 Å²	62.6	15%	0.149	34%	0.34	C	S	.	.			trans	-71.5	145.4	-178.9	32.3	-38.2	0	0	0	111.1	L179 W184 K240 P241 F242	L179-P238 HydrophobicContact CD2-CG 3.64Å; W184-P238 HydrophobicContact CD2-CB 4.31Å; W184-P238 HydrophobicContact CD2-CG 3.63Å; W184-P238 HydrophobicContact CE3-CG 4.15Å; W184-P238 HydrophobicContact CG-CG 3.88Å; W184-P238 HydrophobicContact CH2-CB 4.08Å; W184-P238 HydrophobicContact CH2-CG 4.45Å; W184-P238 HydrophobicContact CZ2-CB 3.79Å; W184-P238 HydrophobicContact CZ2-CG 3.99Å; W184-P238 HydrophobicContact CZ3-CB 4.46Å; P238-K240 PolarHBondContact O-N 2.97Å; P238-P241 HydrophobicContact CG-CG 4.24Å; P238-P241 WeakPolarHBondContact O-CD 3.46Å; P238-F242 VanDerWaalsContact O-CD2 3.22Å; P238-F242 WeakPolarHBondContact O-CD2 3.5Å; P238-F242 VanDerWaalsContact O-CE2 3.27Å; P238-F242 WeakPolarHBondContact O-CE2 3.36Å
239	L	98.3	Very high	97.6	Very high	36 Å²	36	69.6 Å²	69.6	19%	0.188	37%	0.373	C	S	.	.	S	Bend	trans	-67.6	-35.6	178.7	176.4	62.7	0	0	0	113.4	F242 L243 F251 W252	L239-F242 PolarHBondContact O-N 3.46Å; L239-L243 HydrophobicContact CD1-CB 4.26Å; L239-L243 HydrophobicContact CD2-CD2 4.22Å; L239-L243 HydrophobicContact CG-CB 4.12Å; L239-L243 HydrophobicContact CG-CD2 4.49Å; L239-L243 PolarHBondContact O-N 3.32Å; L239-F251 HydrophobicContact CD1-CD1 3.64Å; L239-F251 HydrophobicContact CD1-CE1 3.23Å; L239-F251 HydrophobicContact CD1-CE2 4.18Å; L239-F251 HydrophobicContact CD1-CG 4.27Å; L239-F251 HydrophobicContact CD1-CZ 3.54Å; L239-W252 HydrophobicContact CD1-CH2 4.36Å; L239-W252 HydrophobicContact CD1-CZ2 4.24Å; L239-W252 HydrophobicContact CD2-CZ2 3.84Å; L239-W252 HydrophobicContact CG-CZ2 4.5Å
240	K	97.6	Very high	97.5	Very high	183 Å²	183	69.4 Å²	69.4	80%	0.796	37%	0.369	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52.5	-42.9	-165.8	-178.3	176.1	-180	174.2	0	114.8	P238 F242	P238-K240 PolarHBondContact O-N 2.97Å; K240-F242 PolarHBondContact O-N 3.21Å
241	P	98	Very high	97.5	Very high	25 Å²	25	64.7 Å²	64.7	16%	0.162	35%	0.35	C	S	.	.	T	Hydrogen-bonded Turn	trans	-65	-21.5	178.2	-24.5	37.4	0	0	0	114.7	V175 L179 P238	V175-P241 HydrophobicContact CG1-CB 3.97Å; V175-P241 HydrophobicContact CG2-CB 4.4Å; V175-P241 VanDerWaalsContact CG2-O 3.31Å; V175-P241 WeakPolarHBondContact CG2-O 3.32Å; L179-P241 HydrophobicContact CD2-CG 4.05Å; P238-P241 HydrophobicContact CG-CG 4.24Å; P238-P241 WeakPolarHBondContact O-CD 3.46Å
242	F	98.6	Very high	97.5	Very high	1 Å²	1	68.3 Å²	68.3	0%	0.004	36%	0.362	C	S	.	.	T	Hydrogen-bonded Turn	trans	-99.9	-17	-173.9	-54.8	-90.4	0	0	0	113.2	V175 L179 L221 L224 Y225 Y228 P238 L239 K240 V244 F251	V175-F242 HydrophobicContact CG1-CD1 3.99Å; V175-F242 HydrophobicContact CG1-CE1 3.5Å; V175-F242 HydrophobicContact CG1-CE2 4.3Å; V175-F242 HydrophobicContact CG1-CZ 3.68Å; L179-F242 HydrophobicContact CD1-CE2 4.36Å; L179-F242 HydrophobicContact CD1-CZ 3.94Å; L221-F242 WeakPolarHBondContact CB-O 3.25Å; L224-F242 HydrophobicContact CB-CD1 4.45Å; L224-F242 HydrophobicContact CB-CE1 4.42Å; L224-F242 HydrophobicContact CD2-CD1 4.26Å; L224-F242 HydrophobicContact CD2-CE1 3.95Å; L224-F242 HydrophobicContact CG-CD1 4.4Å; L224-F242 HydrophobicContact CG-CE1 3.96Å; Y225-F242 HydrophobicContact CD2-CB 4.43Å; Y225-F242 HydrophobicContact CD2-CD1 4.33Å; Y225-F242 AromaticContact CD2-CD2 3.65Å; Y225-F242 HydrophobicContact CD2-CD2 3.65Å; Y225-F242 AromaticContact CD2-CE2 3.88Å; Y225-F242 HydrophobicContact CD2-CE2 3.88Å; Y225-F242 AromaticContact CD2-CG 3.89Å; Y225-F242 HydrophobicContact CD2-CG 3.89Å; Y225-F242 HydrophobicContact CD2-CZ 4.3Å; Y225-F242 HydrophobicContact CE2-CD2 4.46Å; Y225-F242 HydrophobicContact CG-CD2 4.5Å; Y225-F242 HydrophobicContact CG-CG 4.3Å; Y228-F242 AromaticContact CD2-CE1 3.58Å; Y228-F242 HydrophobicContact CD2-CE1 3.58Å; Y228-F242 AromaticContact CD2-CZ 3.66Å; Y228-F242 HydrophobicContact CD2-CZ 3.66Å; Y228-F242 AromaticContact CE2-CE1 3.88Å; Y228-F242 HydrophobicContact CE2-CE1 3.88Å; Y228-F242 HydrophobicContact CE2-CZ 4.02Å; Y228-F242 HydrophobicContact CG-CE1 4.32Å; Y228-F242 AromaticContact CG-CZ 3.98Å; Y228-F242 HydrophobicContact CG-CZ 3.98Å; P238-F242 VanDerWaalsContact O-CD2 3.22Å; P238-F242 WeakPolarHBondContact O-CD2 3.5Å; P238-F242 VanDerWaalsContact O-CE2 3.27Å; P238-F242 WeakPolarHBondContact O-CE2 3.36Å; L239-F242 PolarHBondContact O-N 3.46Å; K240-F242 PolarHBondContact O-N 3.21Å; F242-V244 PolarHBondContact O-N 3.46Å; F242-F251 HydrophobicContact CB-CE2 4.26Å; F242-F251 HydrophobicContact CB-CZ 4.34Å
243	L	98.3	Very high	97.6	Very high	41 Å²	41	72.2 Å²	72.2	22%	0.215	38%	0.379	C	S	.	.			trans	-92.2	104.8	-175.1	-175.8	71.4	0	0	0	110.9	L239 E245 K248 F251	L239-L243 HydrophobicContact CD1-CB 4.26Å; L239-L243 HydrophobicContact CD2-CD2 4.22Å; L239-L243 HydrophobicContact CG-CB 4.12Å; L239-L243 HydrophobicContact CG-CD2 4.49Å; L239-L243 PolarHBondContact O-N 3.32Å; L243-E245 HydrophobicContact CD1-CB 4.43Å; L243-K248 HydrophobicContact CD2-CD 4.4Å; L243-K248 HydrophobicContact CD2-CG 3.67Å; L243-F251 HydrophobicContact CD1-CB 3.85Å; L243-F251 HydrophobicContact CD1-CD2 4.2Å; L243-F251 HydrophobicContact CD1-CG 4.1Å
244	V	97.9	Very high	97.7	Very high	45 Å²	45	70.4 Å²	70.4	27%	0.273	37%	0.366	S	S	.	.			trans	-103.6	-7.9	173.4	-64.9	0	0	0	0	113.2	H214 Q217 A218 L221 F242	H214-V244 PolarHBondContact NE2-O 3.24Å; Q217-V244 HydrophobicContact CG-CG1 4.31Å; Q217-V244 HydrophobicContact CG-CG2 4.28Å; A218-V244 HydrophobicContact CB-CG2 3.86Å; L221-V244 HydrophobicContact CD1-CG1 3.59Å; L221-V244 HydrophobicContact CD1-CG2 4.39Å; F242-V244 PolarHBondContact O-N 3.46Å
245	E	95.8	Very high	97.8	Very high	36 Å²	36	67.9 Å²	67.9	17%	0.168	36%	0.355	C	S	.	.	S	Bend	trans	-91.8	152	-179.7	-65.4	172.3	104.8	0	0	111.6	A218 L243 R254	A218-E245 HydrophobicContact CB-CG 3.67Å; L243-E245 HydrophobicContact CD1-CB 4.43Å; E245-R254 VanDerWaalsContact CD-NH2 3.3Å; E245-R254 IonicContact OE1-CZ 3.84Å; E245-R254 IonicContact OE1-NH1 3.93Å; E245-R254 IonicContact OE1-NH2 2.61Å; E245-R254 PolarHBondContact OE1-NH2 3.09Å; E245-R254 IonicContact OE2-CZ 3.83Å; E245-R254 IonicContact OE2-NH1 3.88Å; E245-R254 PolarHBondContact OE2-NH1 2.98Å; E245-R254 IonicContact OE2-NH2 3.04Å; E245-R254 PolarHBondContact OE2-NH2 3.48Å
246	S	93.5	Very high	97.8	Very high	134 Å²	134	65 Å²	65	94%	0.937	34%	0.34	S	S	*	.	S	Bend	trans	-71.2	-35.3	174	-44.5	0	0	0	0	111.9
247	S	95.7	Very high	97.8	Very high	47 Å²	47	65.4 Å²	65.4	33%	0.329	34%	0.343	S	S	.	.			trans	-90.8	116.6	179.8	-178.5	0	0	0	0	111.1	E249 T250	S247-E249 VanDerWaalsContact C-N 3.34Å; S247-E249 PolarHBondContact OG-N 2.85Å; S247-T250 WeakPolarHBondContact CB-OG1 3.39Å; S247-T250 PolarHBondContact OG-N 3.49Å; S247-T250 PolarHBondContact OG-OG1 3.15Å
248	K	97.2	Very high	97.9	Very high	128 Å²	128	64.9 Å²	64.9	56%	0.557	34%	0.341	S	S	*	.	H	α-helix	trans	-71.3	-30.7	172.5	-70.6	-179.2	-178.1	176.9	0	112.4	L243 F251 W252	L243-K248 HydrophobicContact CD2-CD 4.4Å; L243-K248 HydrophobicContact CD2-CG 3.67Å; K248-F251 WeakPolarHBondContact O-CB 3.48Å; K248-F251 PolarHBondContact O-N 3.4Å; K248-W252 PolarHBondContact O-N 3.29Å
249	E	98.2	Very high	97.9	Very high	148 Å²	148	67.3 Å²	67.3	69%	0.692	35%	0.352	S	S	*	.	H	α-helix	trans	-63.5	-44.9	-178.7	-67.1	178.3	178.3	0	0	110.2	S247 F251 W252 D253	S247-E249 VanDerWaalsContact C-N 3.34Å; S247-E249 PolarHBondContact OG-N 2.85Å; E249-F251 VanDerWaalsContact C-N 3.26Å; E249-F251 PolarHBondContact O-N 3.45Å; E249-W252 PolarHBondContact O-N 3.26Å; E249-D253 PolarHBondContact O-N 2.95Å
250	T	97.8	Very high	97.9	Very high	60 Å²	60	72.3 Å²	72.3	37%	0.368	38%	0.379	S	S	.	.	H	α-helix	trans	-57.9	-38.2	176.7	-51.7	0	0	0	0	112.5	S247 R254	S247-T250 WeakPolarHBondContact CB-OG1 3.39Å; S247-T250 PolarHBondContact OG-N 3.49Å; S247-T250 PolarHBondContact OG-OG1 3.15Å; T250-R254 WeakPolarHBondContact O-CB 3.31Å; T250-R254 PolarHBondContact O-N 2.89Å; T250-R254 VanDerWaalsContact O-N 3.09Å
251	F	98.6	Very high	98	Very high	0 Å²	0	68.6 Å²	68.6	0%	0	37%	0.368	C	S	.	.	H	α-helix	trans	-63.8	-45.3	174.6	178.2	-86.8	0	0	0	111.7	T222 Y225 L239 F242 L243 K248 E249 R254 C255	T222-F251 HydrophobicContact CG2-CE2 4.31Å; T222-F251 WeakPolarHBondContact OG1-CD2 3.49Å; Y225-F251 AromaticContact CD1-CE1 3.88Å; Y225-F251 HydrophobicContact CD1-CE1 3.88Å; Y225-F251 AromaticContact CD1-CZ 3.66Å; Y225-F251 HydrophobicContact CD1-CZ 3.66Å; Y225-F251 HydrophobicContact CD2-CZ 4.43Å; Y225-F251 HydrophobicContact CE1-CE1 4.14Å; Y225-F251 HydrophobicContact CE1-CZ 4.34Å; Y225-F251 HydrophobicContact CG-CE1 4.32Å; Y225-F251 AromaticContact CG-CZ 3.71Å; Y225-F251 HydrophobicContact CG-CZ 3.71Å; L239-F251 HydrophobicContact CD1-CD1 3.64Å; L239-F251 HydrophobicContact CD1-CE1 3.23Å; L239-F251 HydrophobicContact CD1-CE2 4.18Å; L239-F251 HydrophobicContact CD1-CG 4.27Å; L239-F251 HydrophobicContact CD1-CZ 3.54Å; F242-F251 HydrophobicContact CB-CE2 4.26Å; F242-F251 HydrophobicContact CB-CZ 4.34Å; L243-F251 HydrophobicContact CD1-CB 3.85Å; L243-F251 HydrophobicContact CD1-CD2 4.2Å; L243-F251 HydrophobicContact CD1-CG 4.1Å; K248-F251 WeakPolarHBondContact O-CB 3.48Å; K248-F251 PolarHBondContact O-N 3.4Å; E249-F251 VanDerWaalsContact C-N 3.26Å; E249-F251 PolarHBondContact O-N 3.45Å; F251-R254 PolarHBondContact O-N 3.36Å; F251-C255 VanDerWaalsContact CE1-SG 3.53Å; F251-C255 PolarHBondContact O-N 3.21Å; F251-C255 PolarHBondContact O-SG 2.92Å
252	W	98.7	Very high	98	Very high	106 Å²	106	67.4 Å²	67.4	40%	0.402	36%	0.36	S	S	.	.	H	α-helix	trans	-71.4	-39.4	-178.8	-67.3	125.9	0	0	0	113.3	Y225 L239 K248 E249 R254 C255 L256	Y225-W252 HydrophobicContact CE1-CH2 4.13Å; Y225-W252 AromaticContact CE1-CZ3 3.77Å; Y225-W252 HydrophobicContact CE1-CZ3 3.77Å; L239-W252 HydrophobicContact CD1-CH2 4.36Å; L239-W252 HydrophobicContact CD1-CZ2 4.24Å; L239-W252 HydrophobicContact CD2-CZ2 3.84Å; L239-W252 HydrophobicContact CG-CZ2 4.5Å; K248-W252 PolarHBondContact O-N 3.29Å; E249-W252 PolarHBondContact O-N 3.26Å; W252-R254 VanDerWaalsContact C-N 3.27Å; W252-R254 PolarHBondContact O-N 2.97Å; W252-C255 HydrophobicContact CE3-CB 4.31Å; W252-C255 WeakPolarHBondContact O-CB 3.44Å; W252-C255 PolarHBondContact O-N 2.9Å; W252-C255 VanDerWaalsContact O-N 3.15Å; W252-L256 PolarHBondContact O-N 3.25Å
253	D	98.7	Very high	98	Very high	103 Å²	103	70.3 Å²	70.3	55%	0.551	38%	0.38	S	S	*	.	H	α-helix	trans	-59.6	-42.3	173.1	-69	-25	0	0	0	110.6	E249 L256 S257	E249-D253 PolarHBondContact O-N 2.95Å; D253-L256 PolarHBondContact O-N 3.08Å; D253-S257 WeakPolarHBondContact O-CB 3.5Å; D253-S257 PolarHBondContact O-N 2.96Å
254	R	98.7	Very high	98	Very high	41 Å²	41	71.7 Å²	71.7	16%	0.155	40%	0.398	C	S	.	.	H	α-helix	trans	-64	-42	174.5	-164.3	-174.6	-57.4	123.8	5.6	111.7	A218 T222 E245 T250 F251 W252 L256 S257 I258	A218-R254 PolarHBondContact O-NH1 3.38Å; T222-R254 HydrophobicContact CG2-CB 4.18Å; T222-R254 HydrophobicContact CG2-CG 4.06Å; T222-R254 PolarHBondContact OG1-NH1 2.95Å; E245-R254 VanDerWaalsContact CD-NH2 3.3Å; E245-R254 IonicContact OE1-CZ 3.84Å; E245-R254 IonicContact OE1-NH1 3.93Å; E245-R254 IonicContact OE1-NH2 2.61Å; E245-R254 PolarHBondContact OE1-NH2 3.09Å; E245-R254 IonicContact OE2-CZ 3.83Å; E245-R254 IonicContact OE2-NH1 3.88Å; E245-R254 PolarHBondContact OE2-NH1 2.98Å; E245-R254 IonicContact OE2-NH2 3.04Å; E245-R254 PolarHBondContact OE2-NH2 3.48Å; T250-R254 WeakPolarHBondContact O-CB 3.31Å; T250-R254 PolarHBondContact O-N 2.89Å; T250-R254 VanDerWaalsContact O-N 3.09Å; F251-R254 PolarHBondContact O-N 3.36Å; W252-R254 VanDerWaalsContact C-N 3.27Å; W252-R254 PolarHBondContact O-N 2.97Å; R254-L256 PolarHBondContact O-N 3.11Å; R254-S257 PolarHBondContact O-N 2.75Å; R254-I258 HydrophobicContact CG-CD1 3.94Å; R254-I258 HydrophobicContact CG-CG1 4.42Å; R254-I258 VanDerWaalsContact O-CG1 3.25Å; R254-I258 WeakPolarHBondContact O-CG1 3.3Å; R254-I258 PolarHBondContact O-N 3.39Å
255	C	98.9	Very high	98.1	Very high	6 Å²	6	73 Å²	73	4%	0.041	40%	0.4	C	S	.	.	H	α-helix	trans	-55.8	-50.8	174	-78.2	0	0	0	0	111.7	T222 L226 F251 W252 S257 I258 I259	T222-C255 VanDerWaalsContact CG2-SG 3.55Å; L226-C255 HydrophobicContact CD2-CB 4.29Å; F251-C255 VanDerWaalsContact CE1-SG 3.53Å; F251-C255 PolarHBondContact O-N 3.21Å; F251-C255 PolarHBondContact O-SG 2.92Å; W252-C255 HydrophobicContact CE3-CB 4.31Å; W252-C255 WeakPolarHBondContact O-CB 3.44Å; W252-C255 PolarHBondContact O-N 2.9Å; W252-C255 VanDerWaalsContact O-N 3.15Å; C255-S257 VanDerWaalsContact C-N 3.35Å; C255-S257 PolarHBondContact O-N 3.31Å; C255-I258 PolarHBondContact O-N 3.18Å; C255-I259 VanDerWaalsContact O-CG1 3.25Å; C255-I259 WeakPolarHBondContact O-CG1 3.39Å; C255-I259 PolarHBondContact O-N 3.2Å
256	L	98.8	Very high	98.2	Very high	117 Å²	117	71.8 Å²	71.8	61%	0.613	39%	0.394	S	S	*	.	H	α-helix	trans	-62.6	-42.1	-179.9	-68.4	175.5	0	0	0	111.8	W252 D253 R254 I259 N260	W252-L256 PolarHBondContact O-N 3.25Å; D253-L256 PolarHBondContact O-N 3.08Å; R254-L256 PolarHBondContact O-N 3.11Å; L256-I259 PolarHBondContact O-N 3.39Å; L256-N260 WeakPolarHBondContact O-CB 3.35Å; L256-N260 PolarHBondContact O-N 2.86Å
257	S	98.8	Very high	98.4	Very high	78 Å²	78	70.5 Å²	70.5	55%	0.545	38%	0.376	S	S	.	.	H	α-helix	trans	-60	-47.1	175.9	-177	0	0	0	0	112.1	D253 R254 C255 N260 L261	D253-S257 WeakPolarHBondContact O-CB 3.5Å; D253-S257 PolarHBondContact O-N 2.96Å; R254-S257 PolarHBondContact O-N 2.75Å; C255-S257 VanDerWaalsContact C-N 3.35Å; C255-S257 PolarHBondContact O-N 3.31Å; S257-N260 PolarHBondContact O-N 2.95Å; S257-L261 WeakPolarHBondContact O-CB 3.25Å; S257-L261 PolarHBondContact O-N 2.85Å
258	I	98.8	Very high	98.6	Very high	4 Å²	4	72 Å²	72	2%	0.021	38%	0.378	C	S	.	.	H	α-helix	trans	-64.5	-42.6	177.8	-65	165.9	0	0	0	110.9	V205 T222 L226 R254 C255 N260 L261 M262	V205-I258 HydrophobicContact CB-CG1 4.48Å; V205-I258 HydrophobicContact CG1-CD1 3.71Å; V205-I258 HydrophobicContact CG1-CG1 3.67Å; V205-I258 HydrophobicContact CG2-CB 4.44Å; V205-I258 HydrophobicContact CG2-CD1 4.49Å; V205-I258 HydrophobicContact CG2-CG1 3.9Å; V205-I258 HydrophobicContact CG2-CG2 3.92Å; T222-I258 HydrophobicContact CG2-CD1 3.71Å; L226-I258 HydrophobicContact CD1-CB 3.61Å; L226-I258 HydrophobicContact CD1-CD1 4.12Å; L226-I258 HydrophobicContact CD1-CG1 4.48Å; L226-I258 HydrophobicContact CD1-CG2 3.41Å; L226-I258 VanDerWaalsContact CD1-CG2 3.41Å; R254-I258 HydrophobicContact CG-CD1 3.94Å; R254-I258 HydrophobicContact CG-CG1 4.42Å; R254-I258 VanDerWaalsContact O-CG1 3.25Å; R254-I258 WeakPolarHBondContact O-CG1 3.3Å; R254-I258 PolarHBondContact O-N 3.39Å; C255-I258 PolarHBondContact O-N 3.18Å; I258-N260 VanDerWaalsContact C-N 3.34Å; I258-N260 PolarHBondContact O-N 3.37Å; I258-L261 PolarHBondContact O-N 2.88Å; I258-M262 HydrophobicContact CG2-CB 4.28Å; I258-M262 HydrophobicContact CG2-CG 3.97Å; I258-M262 VanDerWaalsContact O-CB 3.22Å; I258-M262 WeakPolarHBondContact O-CB 3.43Å; I258-M262 WeakPolarHBondContact O-CG 3.5Å; I258-M262 PolarHBondContact O-N 2.94Å
259	I	98.8	Very high	98.6	Very high	74 Å²	74	66.1 Å²	66.1	38%	0.379	35%	0.352	S	S	.	.	H	α-helix	trans	-60.9	-46	177.9	-70	164.3	0	0	0	110.5	L226 C255 L256 L261 M262 S263	L226-I259 HydrophobicContact CD1-CG1 4.27Å; L226-I259 HydrophobicContact CD2-CD1 3.87Å; L226-I259 HydrophobicContact CD2-CG1 3.97Å; C255-I259 VanDerWaalsContact O-CG1 3.25Å; C255-I259 WeakPolarHBondContact O-CG1 3.39Å; C255-I259 PolarHBondContact O-N 3.2Å; L256-I259 PolarHBondContact O-N 3.39Å; I259-L261 VanDerWaalsContact C-N 3.28Å; I259-L261 PolarHBondContact O-N 3.41Å; I259-M262 PolarHBondContact O-N 3.14Å; I259-S263 WeakPolarHBondContact O-CB 3.12Å; I259-S263 PolarHBondContact O-N 2.99Å; I259-S263 PolarHBondContact O-OG 3.04Å; I259-S263 VanDerWaalsContact O-OG 3.04Å
260	N	98.8	Very high	98.5	Very high	142 Å²	142	60.8 Å²	60.8	76%	0.759	33%	0.329	S	S	*	.	H	α-helix	trans	-60.5	-39.3	178.4	-172.8	62.4	0	0	0	111.8	L256 S257 I258	L256-N260 WeakPolarHBondContact O-CB 3.35Å; L256-N260 PolarHBondContact O-N 2.86Å; S257-N260 PolarHBondContact O-N 2.95Å; I258-N260 VanDerWaalsContact C-N 3.34Å; I258-N260 PolarHBondContact O-N 3.37Å
261	L	98.8	Very high	98.4	Very high	105 Å²	105	62 Å²	62	55%	0.55	34%	0.34	S	S	.	.	H	α-helix	trans	-75.9	-41.4	179	-178.2	64.1	0	0	0	113.5	V205 S257 I258 I259	V205-L261 HydrophobicContact CG2-CD2 4.46Å; S257-L261 WeakPolarHBondContact O-CB 3.25Å; S257-L261 PolarHBondContact O-N 2.85Å; I258-L261 PolarHBondContact O-N 2.88Å; I259-L261 VanDerWaalsContact C-N 3.28Å; I259-L261 PolarHBondContact O-N 3.41Å
262	M	98.8	Very high	98.3	Very high	0 Å²	0	64.5 Å²	64.5	0%	0	35%	0.353	C	S	.	.	H	α-helix	trans	-109.5	-12.7	-161.2	-60.8	-55.4	-63.3	0	0	114.7	M200 L201 D204 V205 I258 I259 A264 K265 M266	M200-M262 HydrophobicContact CE-CE 4.48Å; M200-M262 WeakPolarHBondContact O-CE 3.41Å; M200-M262 HydrophobicContact SD-CE 3.29Å; M200-M262 WeakPolarHBondContact SD-CE 3.3Å; L201-M262 HydrophobicContact CD2-CB 3.73Å; L201-M262 HydrophobicContact CD2-CE 4.13Å; L201-M262 HydrophobicContact CD2-CG 3.93Å; D204-M262 HydrophobicContact CB-CE 3.95Å; D204-M262 HydrophobicContact CB-SD 3.68Å; D204-M262 WeakPolarHBondContact OD2-CE 3.41Å; V205-M262 HydrophobicContact CG2-CG 3.95Å; V205-M262 HydrophobicContact CG2-SD 4.45Å; I258-M262 HydrophobicContact CG2-CB 4.28Å; I258-M262 HydrophobicContact CG2-CG 3.97Å; I258-M262 VanDerWaalsContact O-CB 3.22Å; I258-M262 WeakPolarHBondContact O-CB 3.43Å; I258-M262 WeakPolarHBondContact O-CG 3.5Å; I258-M262 PolarHBondContact O-N 2.94Å; I259-M262 PolarHBondContact O-N 3.14Å; M262-A264 VanDerWaalsContact C-N 3.27Å; M262-A264 PolarHBondContact O-N 3.44Å; M262-A264 VanDerWaalsContact O-N 3.14Å; M262-K265 HydrophobicContact CE-CB 4.11Å; M262-K265 HydrophobicContact CE-CD 3.64Å; M262-K265 HydrophobicContact CE-CG 4.5Å; M262-K265 PolarHBondContact O-N 3.26Å; M262-K265 HydrophobicContact SD-CD 4.33Å; M262-M266 HydrophobicContact CB-CG 4.22Å; M262-M266 HydrophobicContact CB-SD 4.07Å; M262-M266 VanDerWaalsContact O-CG 3.3Å; M262-M266 WeakPolarHBondContact O-CG 3.37Å; M262-M266 PolarHBondContact O-N 2.94Å
263	S	98.7	Very high	98.1	Very high	61 Å²	61	63 Å²	63	43%	0.427	36%	0.357	S	S	.	.	H	α-helix	trans	-50.1	-43	-175.4	51.9	0	0	0	0	113.8	I259 M266 L267	I259-S263 WeakPolarHBondContact O-CB 3.12Å; I259-S263 PolarHBondContact O-N 2.99Å; I259-S263 PolarHBondContact O-OG 3.04Å; I259-S263 VanDerWaalsContact O-OG 3.04Å; S263-M266 PolarHBondContact O-N 3.02Å; S263-L267 PolarHBondContact O-N 3.06Å; S263-L267 VanDerWaalsContact O-N 3.09Å
264	A	98.7	Very high	98	Very high	71 Å²	71	65.3 Å²	65.3	59%	0.587	36%	0.364	S	S	*	.	H	α-helix	trans	-61.6	-45.3	176.5	0	0	0	0	0	112.5	M262 L267 Q268	M262-A264 VanDerWaalsContact C-N 3.27Å; M262-A264 PolarHBondContact O-N 3.44Å; M262-A264 VanDerWaalsContact O-N 3.14Å; A264-L267 PolarHBondContact O-N 2.78Å; A264-Q268 VanDerWaalsContact O-CB 3.31Å; A264-Q268 WeakPolarHBondContact O-CB 3.31Å; A264-Q268 PolarHBondContact O-N 3.38Å
265	K	98.6	Very high	98	Very high	72 Å²	72	64.2 Å²	64.2	31%	0.313	36%	0.36	S	S	.	.	H	α-helix	trans	-70.9	-33.6	178.6	-71.3	175.6	173.1	171.1	0	112.4	M200 D204 M262 L267 Q268 I269	M200-K265 HydrophobicContact CE-CB 4.24Å; M200-K265 HydrophobicContact SD-CB 3.61Å; M200-K265 HydrophobicContact SD-CD 4.4Å; D204-K265 IonicContact OD1-NZ 2.79Å; D204-K265 IonicContact OD2-NZ 3.38Å; D204-K265 PolarHBondContact OD2-NZ 3.2Å; M262-K265 HydrophobicContact CE-CB 4.11Å; M262-K265 HydrophobicContact CE-CD 3.64Å; M262-K265 HydrophobicContact CE-CG 4.5Å; M262-K265 PolarHBondContact O-N 3.26Å; M262-K265 HydrophobicContact SD-CD 4.33Å; K265-L267 VanDerWaalsContact C-N 3.32Å; K265-Q268 PolarHBondContact O-N 3.47Å; K265-I269 WeakPolarHBondContact O-CB 3.41Å; K265-I269 WeakPolarHBondContact O-CG2 3.29Å; K265-I269 PolarHBondContact O-N 3.42Å
266	M	98.6	Very high	97.9	Very high	10 Å²	10	65 Å²	65	5%	0.049	36%	0.363	C	S	.	.	H	α-helix	trans	-62.9	-38.7	174.5	-67.8	168.5	68.6	0	0	111.6	F197 M200 L201 Y230 M262 S263 I269 N270	F197-M266 HydrophobicContact CE1-CE 4.32Å; F197-M266 HydrophobicContact CE1-CG 4.42Å; F197-M266 HydrophobicContact CE2-CB 4.18Å; F197-M266 HydrophobicContact CE2-CG 4.36Å; F197-M266 HydrophobicContact CZ-CB 3.86Å; F197-M266 HydrophobicContact CZ-CE 3.91Å; F197-M266 HydrophobicContact CZ-CG 3.7Å; M200-M266 HydrophobicContact CE-CB 4.44Å; M200-M266 HydrophobicContact CE-CG 3.91Å; L201-M266 HydrophobicContact CD2-CG 3.85Å; L201-M266 HydrophobicContact CD2-SD 4.11Å; Y230-M266 HydrophobicContact CD1-CE 4.31Å; Y230-M266 HydrophobicContact CD2-CE 3.53Å; Y230-M266 HydrophobicContact CE1-CB 4.34Å; Y230-M266 HydrophobicContact CE2-CB 4.37Å; Y230-M266 HydrophobicContact CE2-CE 4.21Å; Y230-M266 HydrophobicContact CG-CE 3.58Å; M262-M266 HydrophobicContact CB-CG 4.22Å; M262-M266 HydrophobicContact CB-SD 4.07Å; M262-M266 VanDerWaalsContact O-CG 3.3Å; M262-M266 WeakPolarHBondContact O-CG 3.37Å; M262-M266 PolarHBondContact O-N 2.94Å; S263-M266 PolarHBondContact O-N 3.02Å; M266-I269 WeakPolarHBondContact O-CG2 3.41Å; M266-N270 PolarHBondContact O-ND2 3.29Å
267	L	98.7	Very high	97.8	Very high	108 Å²	108	62.7 Å²	62.7	57%	0.565	35%	0.354	S	S	*	.	H	α-helix	trans	-73.3	-46.6	172.1	-176.4	62.8	0	0	0	111.5	Y230 S263 A264 K265 I269 N270 S271	Y230-L267 WeakPolarHBondContact OH-CA 3.34Å; S263-L267 PolarHBondContact O-N 3.06Å; S263-L267 VanDerWaalsContact O-N 3.09Å; A264-L267 PolarHBondContact O-N 2.78Å; K265-L267 VanDerWaalsContact C-N 3.32Å; L267-I269 VanDerWaalsContact C-N 3.31Å; L267-I269 PolarHBondContact O-N 2.99Å; L267-N270 PolarHBondContact O-N 3.36Å; L267-S271 PolarHBondContact O-N 3.41Å; L267-S271 PolarHBondContact O-OG 3.32Å
268	Q	98.4	Very high	97.8	Very high	79 Å²	79	64.2 Å²	64.2	37%	0.369	35%	0.352	S	S	.	.	H	α-helix	trans	-57.5	-41.3	-177.4	-172.2	-176.1	8.2	0	0	112.6	A264 K265 N270 S271 D272 Y275	A264-Q268 VanDerWaalsContact O-CB 3.31Å; A264-Q268 WeakPolarHBondContact O-CB 3.31Å; A264-Q268 PolarHBondContact O-N 3.38Å; K265-Q268 PolarHBondContact O-N 3.47Å; Q268-N270 PolarHBondContact O-N 2.93Å; Q268-S271 WeakPolarHBondContact CA-OG 3.41Å; Q268-S271 PolarHBondContact O-N 2.98Å; Q268-S271 PolarHBondContact O-OG 3.49Å; Q268-D272 HydrophobicContact CG-CB 4.37Å; Q268-D272 WeakPolarHBondContact O-CB 3.33Å; Q268-D272 PolarHBondContact O-N 2.82Å; Q268-Y275 HydrophobicContact CB-CD1 4.08Å; Q268-Y275 HydrophobicContact CB-CE1 4.25Å; Q268-Y275 HydrophobicContact CG-CD1 3.7Å; Q268-Y275 HydrophobicContact CG-CE1 4.23Å; Q268-Y275 HydrophobicContact CG-CG 4.17Å
269	I	97.9	Very high	97.7	Very high	3 Å²	3	64 Å²	64	2%	0.015	35%	0.351	C	S	.	.	H	α-helix	trans	-65.5	-20.7	180	-163.1	166.9	0	0	0	113.1	V196 F197 M200 K265 M266 L267 Y275 F276 V279	V196-I269 HydrophobicContact CG1-CD1 4.23Å; F197-I269 HydrophobicContact CD2-CG2 3.57Å; F197-I269 HydrophobicContact CE2-CG2 3.65Å; M200-I269 HydrophobicContact CB-CD1 4.05Å; M200-I269 HydrophobicContact CE-CG2 4.15Å; M200-I269 HydrophobicContact CG-CD1 4.07Å; K265-I269 WeakPolarHBondContact O-CB 3.41Å; K265-I269 WeakPolarHBondContact O-CG2 3.29Å; K265-I269 PolarHBondContact O-N 3.42Å; M266-I269 WeakPolarHBondContact O-CG2 3.41Å; L267-I269 VanDerWaalsContact C-N 3.31Å; L267-I269 PolarHBondContact O-N 2.99Å; I269-Y275 HydrophobicContact CB-CD1 3.85Å; I269-Y275 HydrophobicContact CB-CE1 3.9Å; I269-Y275 HydrophobicContact CG1-CD1 4.26Å; I269-Y275 HydrophobicContact CG1-CE1 4.43Å; I269-F276 HydrophobicContact CD1-CD2 4.28Å; I269-F276 HydrophobicContact CG1-CB 4.13Å; I269-F276 HydrophobicContact CG1-CD2 3.95Å; I269-V279 HydrophobicContact CD1-CB 4.27Å; I269-V279 HydrophobicContact CD1-CG1 4.27Å; I269-V279 HydrophobicContact CD1-CG2 4.24Å
270	N	95.4	Very high	97.7	Very high	37 Å²	37	61 Å²	61	20%	0.198	34%	0.336	C	S	.	.	H	α-helix	trans	-91.2	-30.3	174.1	-75.3	-79.8	0	0	0	112.7	S91 M231 M266 L267 Q268	S91-N270 PolarHBondContact OG-OD1 3.34Å; M231-N270 WeakPolarHBondContact CE-OD1 3.48Å; M231-N270 PolarHBondContact SD-ND2 2.91Å; M231-N270 VanDerWaalsContact SD-ND2 3.41Å; M266-N270 PolarHBondContact O-ND2 3.29Å; L267-N270 PolarHBondContact O-N 3.36Å; Q268-N270 PolarHBondContact O-N 2.93Å
271	S	96.6	Very high	97.5	Very high	86 Å²	86	56.1 Å²	56.1	60%	0.601	31%	0.314	S	S	*	.	H	α-helix	trans	-90.2	-22.8	-178.1	62.3	0	0	0	0	114.4	L267 Q268	L267-S271 PolarHBondContact O-N 3.41Å; L267-S271 PolarHBondContact O-OG 3.32Å; Q268-S271 WeakPolarHBondContact CA-OG 3.41Å; Q268-S271 PolarHBondContact O-N 2.98Å; Q268-S271 PolarHBondContact O-OG 3.49Å
272	D	96.7	Very high	97.5	Very high	51 Å²	51	53.4 Å²	53.4	27%	0.273	30%	0.301	S	S	.	.			trans	-118.8	103.6	-178.6	-178.3	6.2	0	0	0	112	Q268 H274 Y275 F276	Q268-D272 HydrophobicContact CG-CB 4.37Å; Q268-D272 WeakPolarHBondContact O-CB 3.33Å; Q268-D272 PolarHBondContact O-N 2.82Å; D272-H274 PolarHBondContact O-N 2.87Å; D272-H274 WeakPolarHBondContact OD1-CB 3.43Å; D272-H274 IonicContact OD1-CG 3.4Å; D272-H274 PolarHBondContact OD1-N 3.39Å; D272-H274 IonicContact OD1-ND1 3.7Å; D272-H274 PolarHBondContact OD1-ND1 2.93Å; D272-Y275 PolarHBondContact O-N 3.41Å; D272-Y275 PolarHBondContact OD1-N 3.43Å; D272-Y275 WeakPolarHBondContact OD2-CB 3.42Å; D272-F276 PolarHBondContact O-N 2.63Å; D272-F276 VanDerWaalsContact O-N 3.09Å
273	P	94.8	Very high	97.4	Very high	76 Å²	76	53.4 Å²	53.4	49%	0.494	30%	0.301	S	S	.	.	H	α-helix	trans	-60.8	-26.8	176.4	-24.6	34.6	0	0	0	114.4	T277	P273-T277 WeakPolarHBondContact O-CB 3.49Å; P273-T277 PolarHBondContact O-N 2.81Å; P273-T277 PolarHBondContact O-OG1 2.87Å
274	H	96.5	Very high	97.2	Very high	150 Å²	150	53 Å²	53	69%	0.694	29%	0.291	S	S	*	.	H	α-helix	trans	-71.6	-43.5	177.4	-59.9	89.4	0	0	0	110.2	D272 T277 Q278	D272-H274 PolarHBondContact O-N 2.87Å; D272-H274 WeakPolarHBondContact OD1-CB 3.43Å; D272-H274 IonicContact OD1-CG 3.4Å; D272-H274 PolarHBondContact OD1-N 3.39Å; D272-H274 IonicContact OD1-ND1 3.7Å; D272-H274 PolarHBondContact OD1-ND1 2.93Å; H274-T277 PolarHBondContact O-N 2.85Å; H274-Q278 WeakPolarHBondContact O-CB 3.24Å; H274-Q278 PolarHBondContact O-N 3.49Å
275	Y	98.2	Very high	97	Very high	18 Å²	18	52.7 Å²	52.7	7%	0.071	28%	0.28	C	S	.	.	H	α-helix	trans	-60.5	-45.4	173.8	-175.4	-123.9	0	0	0	111.1	R203 Q268 I269 D272 T277 Q278 V279	R203-Y275 PolarHBondContact NH2-OH 2.78Å; Q268-Y275 HydrophobicContact CB-CD1 4.08Å; Q268-Y275 HydrophobicContact CB-CE1 4.25Å; Q268-Y275 HydrophobicContact CG-CD1 3.7Å; Q268-Y275 HydrophobicContact CG-CE1 4.23Å; Q268-Y275 HydrophobicContact CG-CG 4.17Å; I269-Y275 HydrophobicContact CB-CD1 3.85Å; I269-Y275 HydrophobicContact CB-CE1 3.9Å; I269-Y275 HydrophobicContact CG1-CD1 4.26Å; I269-Y275 HydrophobicContact CG1-CE1 4.43Å; D272-Y275 PolarHBondContact O-N 3.41Å; D272-Y275 PolarHBondContact OD1-N 3.43Å; D272-Y275 WeakPolarHBondContact OD2-CB 3.42Å; Y275-T277 VanDerWaalsContact C-N 3.34Å; Y275-T277 PolarHBondContact O-N 2.86Å; Y275-Q278 WeakPolarHBondContact O-CB 3.27Å; Y275-Q278 PolarHBondContact O-N 3.15Å; Y275-V279 HydrophobicContact CD2-CG2 4.23Å; Y275-V279 HydrophobicContact CE1-CG2 4.32Å; Y275-V279 HydrophobicContact CE2-CG2 3.9Å; Y275-V279 WeakPolarHBondContact O-CG2 3.22Å; Y275-V279 PolarHBondContact O-N 3.27Å
276	F	97.6	Very high	96.8	Very high	24 Å²	24	50 Å²	50	11%	0.105	27%	0.268	C	S	.	.	H	α-helix	trans	-55.8	-48.2	172.8	177.8	-90	0	0	0	112.3	A193 V196 I269 D272 Q278 V279 F280	A193-F276 HydrophobicContact CB-CE2 4.08Å; A193-F276 HydrophobicContact CB-CZ 4.06Å; V196-F276 HydrophobicContact CB-CE2 4.06Å; V196-F276 HydrophobicContact CB-CZ 4.41Å; V196-F276 HydrophobicContact CG1-CD2 4.23Å; V196-F276 HydrophobicContact CG1-CE2 3.94Å; V196-F276 HydrophobicContact CG1-CZ 4.42Å; V196-F276 HydrophobicContact CG2-CE2 4.48Å; V196-F276 HydrophobicContact CG2-CZ 4.34Å; I269-F276 HydrophobicContact CD1-CD2 4.28Å; I269-F276 HydrophobicContact CG1-CB 4.13Å; I269-F276 HydrophobicContact CG1-CD2 3.95Å; D272-F276 PolarHBondContact O-N 2.63Å; D272-F276 VanDerWaalsContact O-N 3.09Å; F276-Q278 VanDerWaalsContact C-N 3.3Å; F276-Q278 PolarHBondContact O-N 3.14Å; F276-V279 PolarHBondContact O-N 2.98Å; F276-F280 HydrophobicContact CE1-CB 4.39Å; F276-F280 HydrophobicContact CE1-CD2 4.44Å; F276-F280 VanDerWaalsContact O-CB 3.32Å; F276-F280 WeakPolarHBondContact O-CB 3.35Å; F276-F280 PolarHBondContact O-N 3.29Å
277	T	96.3	Very high	95.9	Very high	68 Å²	68	50.7 Å²	50.7	42%	0.417	27%	0.274	S	S	.	.	H	α-helix	trans	-62.3	-38.7	-179.5	-57.1	0	0	0	0	111.6	P273 H274 Y275 F280 A281	P273-T277 WeakPolarHBondContact O-CB 3.49Å; P273-T277 PolarHBondContact O-N 2.81Å; P273-T277 PolarHBondContact O-OG1 2.87Å; H274-T277 PolarHBondContact O-N 2.85Å; Y275-T277 VanDerWaalsContact C-N 3.34Å; Y275-T277 PolarHBondContact O-N 2.86Å; T277-F280 PolarHBondContact O-N 2.99Å; T277-A281 WeakPolarHBondContact O-CB 3.35Å; T277-A281 PolarHBondContact O-N 2.88Å
278	Q	97.6	Very high	95	Very high	109 Å²	109	51.3 Å²	51.3	51%	0.509	27%	0.274	S	S	.	.	H	α-helix	trans	-62.8	-51.6	174.9	-177.5	-176.3	-9.1	0	0	111	H274 Y275 F276 F280 A281 D282	H274-Q278 WeakPolarHBondContact O-CB 3.24Å; H274-Q278 PolarHBondContact O-N 3.49Å; Y275-Q278 WeakPolarHBondContact O-CB 3.27Å; Y275-Q278 PolarHBondContact O-N 3.15Å; F276-Q278 VanDerWaalsContact C-N 3.3Å; F276-Q278 PolarHBondContact O-N 3.14Å; Q278-F280 VanDerWaalsContact C-N 3.28Å; Q278-F280 PolarHBondContact O-N 3.45Å; Q278-A281 PolarHBondContact O-N 3.43Å; Q278-A281 VanDerWaalsContact O-N 3.14Å; Q278-D282 PolarHBondContact O-N 3.12Å
279	V	98.3	Very high	93.8	Very high	0 Å²	0	52.6 Å²	52.6	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-61.6	-39	179	-178.4	0	0	0	0	111.5	V196 Y199 M200 R203 I269 Y275 F276 D282 L283	V196-V279 HydrophobicContact CG1-CB 3.93Å; V196-V279 HydrophobicContact CG1-CG1 3.58Å; Y199-V279 HydrophobicContact CD1-CG1 3.68Å; Y199-V279 HydrophobicContact CE1-CG1 4.03Å; M200-V279 HydrophobicContact CB-CG1 3.94Å; M200-V279 HydrophobicContact CG-CG1 4.42Å; M200-V279 HydrophobicContact CG-CG2 4.45Å; R203-V279 VanDerWaalsContact NH2-CG2 3.35Å; I269-V279 HydrophobicContact CD1-CB 4.27Å; I269-V279 HydrophobicContact CD1-CG1 4.27Å; I269-V279 HydrophobicContact CD1-CG2 4.24Å; Y275-V279 HydrophobicContact CD2-CG2 4.23Å; Y275-V279 HydrophobicContact CE1-CG2 4.32Å; Y275-V279 HydrophobicContact CE2-CG2 3.9Å; Y275-V279 WeakPolarHBondContact O-CG2 3.22Å; Y275-V279 PolarHBondContact O-N 3.27Å; F276-V279 PolarHBondContact O-N 2.98Å; V279-D282 PolarHBondContact O-N 3.03Å; V279-L283 PolarHBondContact O-N 2.96Å
280	F	97.3	Very high	92.6	Very high	12 Å²	12	55 Å²	55	5%	0.053	29%	0.289	C	S	.	.	H	α-helix	trans	-60.9	-46.6	174.5	177.6	-77	0	0	0	111.4	V138 A140 L145 V196 F276 T277 Q278 L283 K284	V138-F280 HydrophobicContact CB-CD1 4.09Å; V138-F280 HydrophobicContact CB-CE1 3.6Å; V138-F280 HydrophobicContact CB-CZ 4.15Å; V138-F280 HydrophobicContact CG1-CD1 3.75Å; V138-F280 HydrophobicContact CG1-CE1 3.15Å; V138-F280 HydrophobicContact CG1-CZ 4.01Å; A140-F280 HydrophobicContact CB-CE2 4.31Å; A140-F280 HydrophobicContact CB-CZ 3.68Å; L145-F280 HydrophobicContact CD1-CE2 3.96Å; L145-F280 HydrophobicContact CD2-CE2 4.3Å; L145-F280 HydrophobicContact CD2-CZ 4.46Å; V196-F280 HydrophobicContact CG1-CB 4.26Å; V196-F280 HydrophobicContact CG2-CB 4.09Å; V196-F280 HydrophobicContact CG2-CD2 3.61Å; V196-F280 HydrophobicContact CG2-CE2 4.5Å; V196-F280 HydrophobicContact CG2-CG 4.25Å; F276-F280 HydrophobicContact CE1-CB 4.39Å; F276-F280 HydrophobicContact CE1-CD2 4.44Å; F276-F280 VanDerWaalsContact O-CB 3.32Å; F276-F280 WeakPolarHBondContact O-CB 3.35Å; F276-F280 PolarHBondContact O-N 3.29Å; T277-F280 PolarHBondContact O-N 2.99Å; Q278-F280 VanDerWaalsContact C-N 3.28Å; Q278-F280 PolarHBondContact O-N 3.45Å; F280-L283 PolarHBondContact O-N 2.75Å; F280-K284 HydrophobicContact CD1-CD 4.14Å; F280-K284 HydrophobicContact CD1-CG 4.39Å; F280-K284 HydrophobicContact CE1-CD 3.27Å; F280-K284 HydrophobicContact CE1-CG 3.87Å; F280-K284 HydrophobicContact CZ-CD 3.76Å; F280-K284 HydrophobicContact CZ-CG 4.29Å; F280-K284 PolarHBondContact O-N 3.06Å; F280-K284 VanDerWaalsContact O-N 3.09Å
281	A	96	Very high	91.4	Very high	38 Å²	38	57.8 Å²	57.8	31%	0.314	30%	0.301	S	S	.	.	H	α-helix	trans	-64.7	-42.8	178.4	0	0	0	0	0	111.7	T277 Q278 L283 K284 N285	T277-A281 WeakPolarHBondContact O-CB 3.35Å; T277-A281 PolarHBondContact O-N 2.88Å; Q278-A281 PolarHBondContact O-N 3.43Å; Q278-A281 VanDerWaalsContact O-N 3.14Å; A281-L283 VanDerWaalsContact C-N 3.33Å; A281-L283 PolarHBondContact O-N 3.36Å; A281-K284 PolarHBondContact O-N 3.06Å; A281-N285 PolarHBondContact O-N 2.88Å; A281-N285 PolarHBondContact O-ND2 3.31Å
282	D	97.4	Very high	90.3	Very high	49 Å²	49	59.7 Å²	59.7	26%	0.262	30%	0.301	S	S	.	.	H	α-helix	trans	-55.5	-49.4	175.2	-68.5	-20.6	0	0	0	110.7	Y199 R203 Q278 V279 K284 N285 E286	Y199-D282 HydrophobicContact CE1-CB 4.03Å; R203-D282 IonicContact NH1-OD2 3.78Å; R203-D282 PolarHBondContact NH1-OD2 3.39Å; Q278-D282 PolarHBondContact O-N 3.12Å; V279-D282 PolarHBondContact O-N 3.03Å; D282-K284 PolarHBondContact O-N 3.09Å; D282-N285 PolarHBondContact O-N 3.34Å; D282-E286 PolarHBondContact O-N 2.91Å
283	L	97.6	Very high	89.1	Confident	0 Å²	0	65.1 Å²	65.1	0%	0	32%	0.318	C	S	.	.	H	α-helix	trans	-59.2	-47.6	178.2	176.8	56.4	0	0	0	111.8	L145 C148 L149 V195 V196 Y199 V279 F280 A281 N285 E286	L145-L283 HydrophobicContact CB-CD2 4.11Å; L145-L283 HydrophobicContact CD2-CD2 4Å; L145-L283 HydrophobicContact CD2-CG 4.21Å; C148-L283 HydrophobicContact CB-CD1 3.7Å; C148-L283 HydrophobicContact CB-CG 4.12Å; C148-L283 VanDerWaalsContact CB-O 3.27Å; C148-L283 WeakPolarHBondContact CB-O 3.46Å; L149-L283 HydrophobicContact CB-CD1 4.18Å; V195-L283 HydrophobicContact CG1-CD2 4.08Å; V196-L283 HydrophobicContact CG2-CD2 4.23Å; Y199-L283 HydrophobicContact CD1-CB 3.73Å; Y199-L283 HydrophobicContact CD1-CD1 4.34Å; Y199-L283 HydrophobicContact CD1-CG 4.41Å; Y199-L283 HydrophobicContact CD2-CD1 3.68Å; Y199-L283 HydrophobicContact CE1-CB 3.89Å; Y199-L283 HydrophobicContact CE2-CD1 4.14Å; Y199-L283 HydrophobicContact CG-CB 4.06Å; Y199-L283 HydrophobicContact CG-CD1 3.77Å; Y199-L283 HydrophobicContact CG-CD2 4.27Å; Y199-L283 HydrophobicContact CG-CG 4.24Å; V279-L283 PolarHBondContact O-N 2.96Å; F280-L283 PolarHBondContact O-N 2.75Å; A281-L283 VanDerWaalsContact C-N 3.33Å; A281-L283 PolarHBondContact O-N 3.36Å; L283-N285 PolarHBondContact O-N 2.81Å; L283-E286 WeakPolarHBondContact O-CB 3.28Å; L283-E286 PolarHBondContact O-N 3.25Å; L283-E286 VanDerWaalsContact O-N 3.08Å
284	K	94.9	Very high	88.1	Confident	53 Å²	53	64 Å²	64	23%	0.23	31%	0.312	C	S	.	.	H	α-helix	trans	-58.8	-39.2	177.8	-75.9	-166.7	71.4	168.8	0	112.3	Q139 A140 E144 L145 F280 A281 D282 E286 S287	Q139-K284 PolarHBondContact O-NZ 3.41Å; A140-K284 HydrophobicContact CB-CD 3.99Å; A140-K284 HydrophobicContact CB-CG 4.45Å; E144-K284 IonicContact OE1-NZ 3.24Å; L145-K284 HydrophobicContact CD2-CG 3.86Å; F280-K284 HydrophobicContact CD1-CD 4.14Å; F280-K284 HydrophobicContact CD1-CG 4.39Å; F280-K284 HydrophobicContact CE1-CD 3.27Å; F280-K284 HydrophobicContact CE1-CG 3.87Å; F280-K284 HydrophobicContact CZ-CD 3.76Å; F280-K284 HydrophobicContact CZ-CG 4.29Å; F280-K284 PolarHBondContact O-N 3.06Å; F280-K284 VanDerWaalsContact O-N 3.09Å; A281-K284 PolarHBondContact O-N 3.06Å; D282-K284 PolarHBondContact O-N 3.09Å; K284-E286 PolarHBondContact O-N 2.93Å; K284-S287 PolarHBondContact O-N 3.07Å; K284-S287 PolarHBondContact O-OG 2.98Å
285	N	94.3	Very high	87	Confident	64 Å²	64	65 Å²	65	34%	0.342	31%	0.309	S	S	.	.	H	α-helix	trans	-70	-13.3	-179.7	-67	-21.2	0	0	0	113.2	A281 D282 L283 S287 Q288 K289	A281-N285 PolarHBondContact O-N 2.88Å; A281-N285 PolarHBondContact O-ND2 3.31Å; D282-N285 PolarHBondContact O-N 3.34Å; L283-N285 PolarHBondContact O-N 2.81Å; N285-S287 PolarHBondContact O-N 3.38Å; N285-Q288 PolarHBondContact O-N 3.46Å; N285-K289 WeakPolarHBondContact O-CG 3.45Å; N285-K289 PolarHBondContact O-N 3.47Å
286	E	92.9	Very high	85.8	Confident	14 Å²	14	69.5 Å²	69.5	7%	0.065	33%	0.334	C	S	.	.	H	α-helix	trans	-65.8	-25.9	175.7	-62	-65.2	-173.3	0	0	113	F152 R155 Y199 D282 L283 K284 K289	F152-E286 HydrophobicContact CB-CB 4.09Å; F152-E286 HydrophobicContact CB-CG 3.92Å; F152-E286 HydrophobicContact CD2-CG 4.27Å; F152-E286 WeakPolarHBondContact CD2-OE1 3.32Å; F152-E286 HydrophobicContact CG-CG 4.45Å; R155-E286 IonicContact CZ-OE2 3.77Å; R155-E286 PolarHBondContact NH1-O 3.31Å; R155-E286 IonicContact NH1-OE2 2.74Å; R155-E286 PolarHBondContact NH1-OE2 3.19Å; R155-E286 PolarHBondContact NH2-O 3.26Å; Y199-E286 HydrophobicContact CE2-CG 4.08Å; Y199-E286 PolarHBondContact OH-OE1 3.47Å; D282-E286 PolarHBondContact O-N 2.91Å; L283-E286 WeakPolarHBondContact O-CB 3.28Å; L283-E286 PolarHBondContact O-N 3.25Å; L283-E286 VanDerWaalsContact O-N 3.08Å; K284-E286 PolarHBondContact O-N 2.93Å; E286-K289 IonicContact OE1-NZ 3.5Å; E286-K289 IonicContact OE2-NZ 2.8Å; E286-K289 PolarHBondContact OE2-NZ 3.09Å
287	S	81.5	Confident	84.6	Confident	25 Å²	25	73.2 Å²	73.2	18%	0.175	35%	0.354	C	S	.	.	H	α-helix	trans	-78	-37.6	175.5	61.6	0	0	0	0	113.6	E151 K284 N285 K289 E290 E291	E151-S287 WeakPolarHBondContact OE2-CA 3.41Å; E151-S287 WeakPolarHBondContact OE2-CB 3.45Å; K284-S287 PolarHBondContact O-N 3.07Å; K284-S287 PolarHBondContact O-OG 2.98Å; N285-S287 PolarHBondContact O-N 3.38Å; S287-K289 VanDerWaalsContact C-N 3.32Å; S287-K289 PolarHBondContact O-N 3.45Å; S287-E290 PolarHBondContact O-N 3.26Å; S287-E290 VanDerWaalsContact O-N 3.14Å; S287-E291 PolarHBondContact O-N 3.46Å; S287-E291 VanDerWaalsContact O-N 3.14Å
288	Q	77.8	Confident	83.5	Confident	121 Å²	121	74.6 Å²	74.6	57%	0.565	36%	0.358	S	S	*	.	H	α-helix	trans	-63.4	-39.2	179.8	-64	-177.3	-3.9	0	0	111.8	N285 E290 E291 E292	N285-Q288 PolarHBondContact O-N 3.46Å; Q288-E290 PolarHBondContact O-N 3.34Å; Q288-E291 PolarHBondContact O-N 3.12Å; Q288-E292 WeakPolarHBondContact O-CB 3.14Å; Q288-E292 PolarHBondContact O-N 3.19Å
289	K	74.9	Confident	82	Confident	106 Å²	106	71 Å²	71	46%	0.461	35%	0.35	S	S	.	.	H	α-helix	trans	-60.9	-33.1	176.7	-67.3	173.2	-168.1	165.9	0	112.5	N285 E286 S287 R293	N285-K289 WeakPolarHBondContact O-CG 3.45Å; N285-K289 PolarHBondContact O-N 3.47Å; E286-K289 IonicContact OE1-NZ 3.5Å; E286-K289 IonicContact OE2-NZ 2.8Å; E286-K289 PolarHBondContact OE2-NZ 3.09Å; S287-K289 VanDerWaalsContact C-N 3.32Å; S287-K289 PolarHBondContact O-N 3.45Å; K289-R293 WeakPolarHBondContact O-CB 3.45Å; K289-R293 PolarHBondContact O-N 2.82Å
290	E	71.5	Confident	80.6	Confident	53 Å²	53	76 Å²	76	25%	0.248	38%	0.376	C	S	.	.	H	α-helix	trans	-78.2	-41.2	-179.8	-168.3	149.9	159.6	0	0	112.5	E151 R155 S287 Q288 E292 R293 S294	E151-E290 WeakPolarHBondContact CB-OE2 3.41Å; E151-E290 WeakPolarHBondContact CG-OE2 3.31Å; R155-E290 IonicContact NH2-OE2 2.72Å; R155-E290 PolarHBondContact NH2-OE2 3.01Å; S287-E290 PolarHBondContact O-N 3.26Å; S287-E290 VanDerWaalsContact O-N 3.14Å; Q288-E290 PolarHBondContact O-N 3.34Å; E290-E292 VanDerWaalsContact C-N 3.35Å; E290-R293 PolarHBondContact O-N 3.04Å; E290-S294 WeakPolarHBondContact O-CB 3.11Å; E290-S294 PolarHBondContact O-N 3.28Å; E290-S294 PolarHBondContact O-OG 3.29Å
291	E	71.4	Confident	79	Confident	96 Å²	96	78.9 Å²	78.9	45%	0.449	39%	0.392	S	S	.	.	H	α-helix	trans	-60.9	-44.3	172.8	-74	-167.4	-165.8	0	0	111.8	S287 Q288 S294 R295	S287-E291 PolarHBondContact O-N 3.46Å; S287-E291 VanDerWaalsContact O-N 3.14Å; Q288-E291 PolarHBondContact O-N 3.12Å; E291-S294 PolarHBondContact O-N 2.95Å; E291-R295 WeakPolarHBondContact O-CB 3.47Å; E291-R295 VanDerWaalsContact O-CG 3.25Å; E291-R295 WeakPolarHBondContact O-CG 3.37Å; E291-R295 PolarHBondContact O-N 2.83Å; E291-R295 IonicContact OE2-CZ 3.84Å; E291-R295 IonicContact OE2-NH2 2.9Å; E291-R295 PolarHBondContact OE2-NH2 3.34Å
292	E	71.9	Confident	77.6	Confident	126 Å²	126	86.1 Å²	86.1	59%	0.589	41%	0.411	S	S	*	.	H	α-helix	trans	-62.5	-46	178.7	-172.3	172.4	-164.9	0	0	111.4	Q288 E290 S294 R295 L296	Q288-E292 WeakPolarHBondContact O-CB 3.14Å; Q288-E292 PolarHBondContact O-N 3.19Å; E290-E292 VanDerWaalsContact C-N 3.35Å; E292-S294 VanDerWaalsContact C-N 3.31Å; E292-S294 PolarHBondContact O-N 3.35Å; E292-R295 PolarHBondContact O-N 2.89Å; E292-L296 HydrophobicContact CG-CD1 4.4Å; E292-L296 WeakPolarHBondContact O-CG 3.43Å; E292-L296 PolarHBondContact O-N 3.19Å
293	R	73.3	Confident	75.9	Confident	166 Å²	166	92.5 Å²	92.5	63%	0.626	43%	0.432	S	S	*	.	H	α-helix	trans	-58.7	-43.1	174.4	-174.6	-179.1	178.3	166.2	1.2	111.9	K289 E290 L296 L297	K289-R293 WeakPolarHBondContact O-CB 3.45Å; K289-R293 PolarHBondContact O-N 2.82Å; E290-R293 PolarHBondContact O-N 3.04Å; R293-L296 PolarHBondContact O-N 2.79Å; R293-L297 HydrophobicContact CG-CD1 4.34Å; R293-L297 WeakPolarHBondContact O-CG 3.49Å; R293-L297 PolarHBondContact O-N 3.41Å; R293-L297 VanDerWaalsContact O-N 3.09Å
294	S	73.1	Confident	74.3	Confident	53 Å²	53	97.2 Å²	97.2	37%	0.371	46%	0.46	S	S	.	.	H	α-helix	trans	-65.3	-41.9	178.9	-59.9	0	0	0	0	111.7	E290 E291 E292 L297 I298	E290-S294 WeakPolarHBondContact O-CB 3.11Å; E290-S294 PolarHBondContact O-N 3.28Å; E290-S294 PolarHBondContact O-OG 3.29Å; E291-S294 PolarHBondContact O-N 2.95Å; E292-S294 VanDerWaalsContact C-N 3.31Å; E292-S294 PolarHBondContact O-N 3.35Å; S294-L297 PolarHBondContact O-N 3.29Å; S294-I298 WeakPolarHBondContact O-CD1 3.47Å; S294-I298 VanDerWaalsContact O-CG1 3.29Å; S294-I298 WeakPolarHBondContact O-CG1 3.41Å; S294-I298 PolarHBondContact O-N 2.98Å
295	R	73.1	Confident	72.8	Confident	170 Å²	170	102.9 Å²	102.9	64%	0.642	48%	0.48	S	S	*	.	H	α-helix	trans	-63.1	-41.6	175.7	-71.8	173.8	-166.2	-171	9.3	112	E291 E292 I298 G299	E291-R295 WeakPolarHBondContact O-CB 3.47Å; E291-R295 VanDerWaalsContact O-CG 3.25Å; E291-R295 WeakPolarHBondContact O-CG 3.37Å; E291-R295 PolarHBondContact O-N 2.83Å; E291-R295 IonicContact OE2-CZ 3.84Å; E291-R295 IonicContact OE2-NH2 2.9Å; E291-R295 PolarHBondContact OE2-NH2 3.34Å; E292-R295 PolarHBondContact O-N 2.89Å; R295-I298 PolarHBondContact O-N 3.35Å; R295-G299 PolarHBondContact O-N 3.09Å
296	L	73.3	Confident	71.2	Confident	112 Å²	112	103.7 Å²	103.7	59%	0.586	50%	0.496	S	S	*	.	H	α-helix	trans	-63.2	-41.9	176.6	-70.9	172.3	0	0	0	112	E292 R293 G299 L300	E292-L296 HydrophobicContact CG-CD1 4.4Å; E292-L296 WeakPolarHBondContact O-CG 3.43Å; E292-L296 PolarHBondContact O-N 3.19Å; R293-L296 PolarHBondContact O-N 2.79Å; L296-G299 PolarHBondContact O-N 3.5Å; L296-L300 WeakPolarHBondContact O-CG 3.44Å; L296-L300 PolarHBondContact O-N 2.85Å
297	L	71.9	Confident	69.9	Low	103 Å²	103	110.1 Å²	110.1	54%	0.539	53%	0.529	S	S	.	.	H	α-helix	trans	-63.8	-43.1	176.3	-72.9	167.2	0	0	0	112.2	R293 S294 G299 L300 D301	R293-L297 HydrophobicContact CG-CD1 4.34Å; R293-L297 WeakPolarHBondContact O-CG 3.49Å; R293-L297 PolarHBondContact O-N 3.41Å; R293-L297 VanDerWaalsContact O-N 3.09Å; S294-L297 PolarHBondContact O-N 3.29Å; L297-G299 VanDerWaalsContact C-N 3.33Å; L297-G299 PolarHBondContact O-N 3.5Å; L297-L300 PolarHBondContact O-N 2.86Å; L297-D301 PolarHBondContact O-N 3.25Å; L297-D301 VanDerWaalsContact O-N 3.09Å
298	I	73.6	Confident	68.5	Low	97 Å²	97	115.5 Å²	115.5	50%	0.497	58%	0.575	S	S	.	*	H	α-helix	trans	-64.7	-38.7	175.9	-65.5	163.5	0	0	0	111.1	S294 R295 D301 R302	S294-I298 WeakPolarHBondContact O-CD1 3.47Å; S294-I298 VanDerWaalsContact O-CG1 3.29Å; S294-I298 WeakPolarHBondContact O-CG1 3.41Å; S294-I298 PolarHBondContact O-N 2.98Å; R295-I298 PolarHBondContact O-N 3.35Å; I298-D301 PolarHBondContact O-N 3.35Å; I298-R302 WeakPolarHBondContact O-CG 3.46Å; I298-R302 PolarHBondContact O-N 3.06Å; I298-R302 VanDerWaalsContact O-N 3.07Å
299	G	66.4	Low	68	Low	32 Å²	32	115.2 Å²	115.2	33%	0.33	58%	0.576	S	S	.	*	H	α-helix	trans	-65.1	-37.7	177.1	0	0	0	0	0	113.3	R295 L296 L297 R303	R295-G299 PolarHBondContact O-N 3.09Å; L296-G299 PolarHBondContact O-N 3.5Å; L297-G299 VanDerWaalsContact C-N 3.33Å; L297-G299 PolarHBondContact O-N 3.5Å; G299-R303 PolarHBondContact O-N 3.11Å
300	L	67.6	Low	67.6	Low	105 Å²	105	115.7 Å²	115.7	55%	0.55	58%	0.582	S	S	.	*	H	α-helix	trans	-67.7	-45.8	174.9	-74.5	165.6	0	0	0	111.7	L296 L297 R302 R303 V304	L296-L300 WeakPolarHBondContact O-CG 3.44Å; L296-L300 PolarHBondContact O-N 2.85Å; L297-L300 PolarHBondContact O-N 2.86Å; L300-R302 VanDerWaalsContact C-N 3.34Å; L300-R302 PolarHBondContact O-N 3.37Å; L300-R303 PolarHBondContact O-N 3.26Å; L300-R303 VanDerWaalsContact O-N 3.12Å; L300-V304 WeakPolarHBondContact O-CG2 3.36Å; L300-V304 PolarHBondContact O-N 3.36Å
301	D	63.9	Low	67.4	Low	73 Å²	73	119.2 Å²	119.2	39%	0.39	60%	0.6	S	S	.	*	H	α-helix	trans	-61.4	-41.1	178.3	-176.6	24.5	0	0	0	111.9	L297 I298 R303 V304 R305	L297-D301 PolarHBondContact O-N 3.25Å; L297-D301 VanDerWaalsContact O-N 3.09Å; I298-D301 PolarHBondContact O-N 3.35Å; D301-R303 PolarHBondContact O-N 3.35Å; D301-V304 PolarHBondContact O-N 3.2Å; D301-R305 WeakPolarHBondContact O-CG 3.42Å; D301-R305 PolarHBondContact O-N 3.24Å; D301-R305 IonicContact OD1-CZ 3.75Å; D301-R305 IonicContact OD1-NE 3.09Å; D301-R305 PolarHBondContact OD1-NE 3.35Å; D301-R305 VanDerWaalsContact OD1-NE 3.09Å; D301-R305 IonicContact OD1-NH2 3.53Å; D301-R305 IonicContact OD2-CZ 3.49Å; D301-R305 IonicContact OD2-NE 3.56Å; D301-R305 IonicContact OD2-NH2 2.68Å; D301-R305 PolarHBondContact OD2-NH2 3.5Å
302	R	66.8	Low	67.2	Low	191 Å²	191	120.5 Å²	120.5	72%	0.721	61%	0.609	S	S	*	*	H	α-helix	trans	-63.6	-36.5	173.3	-75	-175.5	-179.3	-167.2	0.7	113.4	I298 L300 A306	I298-R302 WeakPolarHBondContact O-CG 3.46Å; I298-R302 PolarHBondContact O-N 3.06Å; I298-R302 VanDerWaalsContact O-N 3.07Å; L300-R302 VanDerWaalsContact C-N 3.34Å; L300-R302 PolarHBondContact O-N 3.37Å; R302-A306 WeakPolarHBondContact O-CB 3.32Å; R302-A306 PolarHBondContact O-N 3.41Å
303	R	62.7	Low	66.9	Low	182 Å²	182	120.2 Å²	120.2	69%	0.687	61%	0.61	S	S	*	*	H	α-helix	trans	-69.8	-41	175.4	-78.8	-174.3	-170.8	-176.5	3.7	111.8	G299 L300 D301 R305 A306 I307	G299-R303 PolarHBondContact O-N 3.11Å; L300-R303 PolarHBondContact O-N 3.26Å; L300-R303 VanDerWaalsContact O-N 3.12Å; D301-R303 PolarHBondContact O-N 3.35Å; R303-R305 VanDerWaalsContact C-N 3.34Å; R303-R305 PolarHBondContact O-N 3.3Å; R303-A306 PolarHBondContact O-N 2.88Å; R303-I307 WeakPolarHBondContact O-CD1 3.47Å; R303-I307 VanDerWaalsContact O-CG1 3.28Å; R303-I307 WeakPolarHBondContact O-CG1 3.3Å; R303-I307 PolarHBondContact O-N 3.02Å
304	V	63.5	Low	66.5	Low	99 Å²	99	117.1 Å²	117.1	60%	0.6	61%	0.609	S	S	*	*	H	α-helix	trans	-61.8	-42.8	177.4	172.3	0	0	0	0	110.9	L300 D301 A306 I307 A308	L300-V304 WeakPolarHBondContact O-CG2 3.36Å; L300-V304 PolarHBondContact O-N 3.36Å; D301-V304 PolarHBondContact O-N 3.2Å; V304-A306 VanDerWaalsContact C-N 3.29Å; V304-A306 PolarHBondContact O-N 3.31Å; V304-I307 PolarHBondContact O-N 3.4Å; V304-A308 PolarHBondContact O-N 3.49Å
305	R	63.3	Low	66	Low	172 Å²	172	121.7 Å²	121.7	65%	0.649	63%	0.626	S	S	*	*	H	α-helix	trans	-70.1	-19.2	175.8	-65.6	-175.6	-146.7	-167.5	4.8	115	D301 R303	D301-R305 WeakPolarHBondContact O-CG 3.42Å; D301-R305 PolarHBondContact O-N 3.24Å; D301-R305 IonicContact OD1-CZ 3.75Å; D301-R305 IonicContact OD1-NE 3.09Å; D301-R305 PolarHBondContact OD1-NE 3.35Å; D301-R305 VanDerWaalsContact OD1-NE 3.09Å; D301-R305 IonicContact OD1-NH2 3.53Å; D301-R305 IonicContact OD2-CZ 3.49Å; D301-R305 IonicContact OD2-NE 3.56Å; D301-R305 IonicContact OD2-NH2 2.68Å; D301-R305 PolarHBondContact OD2-NH2 3.5Å; R303-R305 VanDerWaalsContact C-N 3.34Å; R303-R305 PolarHBondContact O-N 3.3Å
306	A	61.6	Low	65.4	Low	82 Å²	82	118 Å²	118	68%	0.678	63%	0.625	S	S	*	*	H	α-helix	trans	-87.3	-10.7	177.8	0	0	0	0	0	113.2	R302 R303 V304	R302-A306 WeakPolarHBondContact O-CB 3.32Å; R302-A306 PolarHBondContact O-N 3.41Å; R303-A306 PolarHBondContact O-N 2.88Å; V304-A306 VanDerWaalsContact C-N 3.29Å; V304-A306 PolarHBondContact O-N 3.31Å
307	I	64.1	Low	64.8	Low	148 Å²	148	118.5 Å²	118.5	76%	0.759	63%	0.628	S	S	*	*	H	α-helix	trans	-105.7	-10.4	-178.8	-60.6	165.2	0	0	0	111.2	R303 V304	R303-I307 WeakPolarHBondContact O-CD1 3.47Å; R303-I307 VanDerWaalsContact O-CG1 3.28Å; R303-I307 WeakPolarHBondContact O-CG1 3.3Å; R303-I307 PolarHBondContact O-N 3.02Å; V304-I307 PolarHBondContact O-N 3.4Å
308	A	52.1	Low	64.1	Low	138 Å²	138	119.9 Å²	119.9	100%	1.141	64%	0.636	S	S	*	*			trans	-96	0	171.9	0	0	0	0	0	110.8	V304	V304-A308 PolarHBondContact O-N 3.49Å

Retrieved 308 of 308 residues in 317.2 ms (Link to these results)

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