A0A087YQA2_POEFO Loading...

G protein-coupled receptor 27

AlphaFold DB (A0A3B3V1B4), UniProt , Accession A0A087YQA2, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 371 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	46.6	Very low	51.4	Low	234 Å²	234	115.4 Å²	115.4	100%	1.153	65%	0.645	S	S	*	*				0	31.4	0	-67.6	177.9	-177.7	0	0	112.4
2	A	45.9	Very low	52.4	Low	76 Å²	76	110.8 Å²	110.8	63%	0.628	63%	0.633	S	S	*	*			trans	-103.8	-4.6	-178.2	0	0	0	0	0	114.5
3	N	48	Very low	53.4	Low	138 Å²	138	106.1 Å²	106.1	74%	0.738	61%	0.611	S	S	*	*	H	α-helix	trans	-88.5	-10.7	-174.8	-108.6	19.6	0	0	0	114.8
4	T	52.8	Low	54.3	Low	113 Å²	113	107.5 Å²	107.5	69%	0.693	61%	0.614	S	S	*	*	H	α-helix	trans	-91	-21.4	-173.9	39.6	0	0	0	0	113.5	G8	T4-G8 PolarHBondContact O-N 3.44Å
5	T	53.7	Low	55.4	Low	95 Å²	95	109.3 Å²	109.3	58%	0.583	62%	0.615	S	S	*	*	H	α-helix	trans	-83.1	-41.3	179.5	44.6	0	0	0	0	112.5	F7 G8 E9	T5-F7 PolarHBondContact O-N 2.97Å; T5-G8 PolarHBondContact O-N 3.02Å; T5-E9 PolarHBondContact O-N 3.02Å; T5-E9 VanDerWaalsContact O-N 3.11Å
6	E	49.7	Very low	56.4	Low	139 Å²	139	107.1 Å²	107.1	65%	0.65	61%	0.608	S	S	*	*	H	α-helix	trans	-67.3	-34.6	176.7	-68.1	-168.8	147.7	0	0	112.6	G8 S10	E6-G8 VanDerWaalsContact C-N 3.34Å; E6-S10 WeakPolarHBondContact O-CB 3.3Å; E6-S10 PolarHBondContact O-N 3.14Å
7	F	48.3	Very low	57.3	Low	166 Å²	166	111 Å²	111	73%	0.728	61%	0.613	S	S	*	*	H	α-helix	trans	-69.9	-32.3	175.8	-142.1	-88.4	0	0	0	111.9	T5 S11	T5-F7 PolarHBondContact O-N 2.97Å; F7-S11 VanDerWaalsContact O-CB 3.29Å; F7-S11 WeakPolarHBondContact O-CB 3.48Å; F7-S11 PolarHBondContact O-N 2.82Å; F7-S11 PolarHBondContact O-OG 2.84Å
8	G	50.5	Low	58.3	Low	34 Å²	34	108.1 Å²	108.1	35%	0.351	61%	0.606	S	S	.	*	H	α-helix	trans	-69.4	-41.8	175.1	0	0	0	0	0	113	T4 T5 E6 S11 A12	T4-G8 PolarHBondContact O-N 3.44Å; T5-G8 PolarHBondContact O-N 3.02Å; E6-G8 VanDerWaalsContact C-N 3.34Å; G8-S11 WeakPolarHBondContact CA-OG 3.19Å; G8-S11 PolarHBondContact O-OG 3.02Å; G8-S11 VanDerWaalsContact O-OG 3.04Å; G8-A12 VanDerWaalsContact O-CB 3.25Å; G8-A12 WeakPolarHBondContact O-CB 3.21Å; G8-A12 PolarHBondContact O-N 2.84Å
9	E	53	Low	59.5	Low	149 Å²	149	106.4 Å²	106.4	70%	0.696	60%	0.602	S	S	*	*	H	α-helix	trans	-71.1	-39	175.8	-72.7	-177.5	153.8	0	0	112.5	T5 S13	T5-E9 PolarHBondContact O-N 3.02Å; T5-E9 VanDerWaalsContact O-N 3.11Å; E9-S13 WeakPolarHBondContact O-CB 3.3Å; E9-S13 PolarHBondContact O-N 3.32Å; E9-S13 PolarHBondContact O-OG 2.95Å
10	S	56	Low	60.7	Low	75 Å²	75	105 Å²	105	52%	0.524	60%	0.595	S	S	.	*	H	α-helix	trans	-68.4	-32.9	176	-167.9	0	0	0	0	112.9	E6 S13 L14	E6-S10 WeakPolarHBondContact O-CB 3.3Å; E6-S10 PolarHBondContact O-N 3.14Å; S10-S13 WeakPolarHBondContact CA-OG 3.46Å; S10-S13 PolarHBondContact O-OG 3.36Å; S10-L14 VanDerWaalsContact O-CB 3.3Å; S10-L14 WeakPolarHBondContact O-CB 3.38Å; S10-L14 PolarHBondContact O-N 3.31Å; S10-L14 VanDerWaalsContact O-N 3.15Å
11	S	61.3	Low	61.9	Low	50 Å²	50	102.2 Å²	102.2	35%	0.35	59%	0.586	S	S	.	*	H	α-helix	trans	-78.5	-38.7	176.6	51.6	0	0	0	0	112.5	F7 G8 L14 H15	F7-S11 VanDerWaalsContact O-CB 3.29Å; F7-S11 WeakPolarHBondContact O-CB 3.48Å; F7-S11 PolarHBondContact O-N 2.82Å; F7-S11 PolarHBondContact O-OG 2.84Å; G8-S11 WeakPolarHBondContact CA-OG 3.19Å; G8-S11 PolarHBondContact O-OG 3.02Å; G8-S11 VanDerWaalsContact O-OG 3.04Å; S11-L14 PolarHBondContact O-N 3.13Å; S11-H15 WeakPolarHBondContact O-CB 3.28Å; S11-H15 PolarHBondContact O-CD2 3.43Å; S11-H15 VanDerWaalsContact O-CD2 3.23Å; S11-H15 PolarHBondContact O-N 3.43Å
12	A	63.1	Low	63.9	Low	61 Å²	61	93 Å²	93	50%	0.504	54%	0.544	S	S	.	.	H	α-helix	trans	-65	-41.4	174.8	0	0	0	0	0	112.1	G8 S16	G8-A12 VanDerWaalsContact O-CB 3.25Å; G8-A12 WeakPolarHBondContact O-CB 3.21Å; G8-A12 PolarHBondContact O-N 2.84Å; A12-S16 WeakPolarHBondContact O-CB 3.22Å; A12-S16 PolarHBondContact O-N 2.9Å
13	S	65.2	Low	66	Low	49 Å²	49	91.9 Å²	91.9	34%	0.343	54%	0.535	S	S	.	.	H	α-helix	trans	-65.2	-45.9	174.1	52.2	0	0	0	0	111.5	E9 S10 H15 S16 Y17	E9-S13 WeakPolarHBondContact O-CB 3.3Å; E9-S13 PolarHBondContact O-N 3.32Å; E9-S13 PolarHBondContact O-OG 2.95Å; S10-S13 WeakPolarHBondContact CA-OG 3.46Å; S10-S13 PolarHBondContact O-OG 3.36Å; S13-H15 PolarHBondContact O-N 3.44Å; S13-S16 PolarHBondContact O-N 3.37Å; S13-S16 VanDerWaalsContact O-N 3.16Å; S13-Y17 WeakPolarHBondContact O-CD2 3.44Å; S13-Y17 PolarHBondContact O-N 3.48Å
14	L	66.7	Low	68.1	Low	126 Å²	126	90.1 Å²	90.1	66%	0.66	53%	0.529	S	S	*	.	H	α-helix	trans	-60.2	-42	177.6	-156.3	85.6	0	0	0	112.6	S10 S11 Y17 A18	S10-L14 VanDerWaalsContact O-CB 3.3Å; S10-L14 WeakPolarHBondContact O-CB 3.38Å; S10-L14 PolarHBondContact O-N 3.31Å; S10-L14 VanDerWaalsContact O-N 3.15Å; S11-L14 PolarHBondContact O-N 3.13Å; L14-Y17 PolarHBondContact O-N 3.27Å; L14-A18 WeakPolarHBondContact O-CB 3.14Å; L14-A18 PolarHBondContact O-N 3.36Å
15	H	69.6	Low	69.9	Low	135 Å²	135	86.5 Å²	86.5	63%	0.625	50%	0.504	S	S	*	.	H	α-helix	trans	-64.3	-42.2	174.2	-86.2	-64.4	0	0	0	112.2	S11 S13 A18 S19	S11-H15 WeakPolarHBondContact O-CB 3.28Å; S11-H15 PolarHBondContact O-CD2 3.43Å; S11-H15 VanDerWaalsContact O-CD2 3.23Å; S11-H15 PolarHBondContact O-N 3.43Å; S13-H15 PolarHBondContact O-N 3.44Å; H15-A18 PolarHBondContact O-N 2.88Å; H15-S19 WeakPolarHBondContact O-CB 3.45Å; H15-S19 PolarHBondContact O-N 2.85Å; H15-S19 PolarHBondContact O-OG 2.89Å; H15-S19 VanDerWaalsContact O-OG 3.06Å
16	S	72.6	Confident	71.9	Confident	73 Å²	73	84.4 Å²	84.4	51%	0.51	49%	0.489	S	S	.	.	H	α-helix	trans	-63.9	-42	176.2	-170.3	0	0	0	0	112.3	A12 S13 S19 T20	A12-S16 WeakPolarHBondContact O-CB 3.22Å; A12-S16 PolarHBondContact O-N 2.9Å; S13-S16 PolarHBondContact O-N 3.37Å; S13-S16 VanDerWaalsContact O-N 3.16Å; S16-S19 PolarHBondContact O-N 3.33Å; S16-T20 WeakPolarHBondContact O-CB 3.38Å; S16-T20 WeakPolarHBondContact O-CG2 3.47Å; S16-T20 PolarHBondContact O-N 2.84Å; S16-T20 PolarHBondContact O-OG1 3.13Å
17	Y	71.9	Confident	74	Confident	174 Å²	174	80.7 Å²	80.7	68%	0.682	48%	0.482	S	S	*	.	H	α-helix	trans	-64.1	-42.5	174.2	-81.2	-69.3	0	0	0	112.2	S13 L14 T20 A21	S13-Y17 WeakPolarHBondContact O-CD2 3.44Å; S13-Y17 PolarHBondContact O-N 3.48Å; L14-Y17 PolarHBondContact O-N 3.27Å; Y17-T20 WeakPolarHBondContact CA-OG1 3.31Å; Y17-T20 PolarHBondContact O-N 3.4Å; Y17-T20 PolarHBondContact O-OG1 3.44Å; Y17-A21 VanDerWaalsContact O-CB 3.28Å; Y17-A21 WeakPolarHBondContact O-CB 3.25Å; Y17-A21 PolarHBondContact O-N 2.87Å
18	A	75	Confident	76.2	Confident	59 Å²	59	74.4 Å²	74.4	49%	0.488	46%	0.459	S	S	.	.	H	α-helix	trans	-65.3	-42	177.2	0	0	0	0	0	112.3	L14 H15 A21 S22	L14-A18 WeakPolarHBondContact O-CB 3.14Å; L14-A18 PolarHBondContact O-N 3.36Å; H15-A18 PolarHBondContact O-N 2.88Å; A18-A21 PolarHBondContact O-N 2.9Å; A18-S22 PolarHBondContact O-N 2.83Å; A18-S22 PolarHBondContact O-OG 3.41Å
19	S	80.1	Confident	78.3	Confident	76 Å²	76	72.8 Å²	72.8	53%	0.531	44%	0.442	S	S	.	.	H	α-helix	trans	-68.1	-36.8	177.4	-63.1	0	0	0	0	113.3	H15 S16 S22 A23	H15-S19 WeakPolarHBondContact O-CB 3.45Å; H15-S19 PolarHBondContact O-N 2.85Å; H15-S19 PolarHBondContact O-OG 2.89Å; H15-S19 VanDerWaalsContact O-OG 3.06Å; S16-S19 PolarHBondContact O-N 3.33Å; S19-S22 PolarHBondContact O-OG 3Å; S19-S22 VanDerWaalsContact O-OG 3.09Å; S19-A23 WeakPolarHBondContact O-CB 3.5Å; S19-A23 PolarHBondContact O-N 2.89Å; S19-A23 VanDerWaalsContact O-N 3.17Å
20	T	84.9	Confident	80.4	Confident	77 Å²	77	66.8 Å²	66.8	47%	0.472	42%	0.42	S	S	.	.	H	α-helix	trans	-71.6	-39.6	175.5	48.6	0	0	0	0	111.7	S16 Y17 A23 V24	S16-T20 WeakPolarHBondContact O-CB 3.38Å; S16-T20 WeakPolarHBondContact O-CG2 3.47Å; S16-T20 PolarHBondContact O-N 2.84Å; S16-T20 PolarHBondContact O-OG1 3.13Å; Y17-T20 WeakPolarHBondContact CA-OG1 3.31Å; Y17-T20 PolarHBondContact O-N 3.4Å; Y17-T20 PolarHBondContact O-OG1 3.44Å; T20-A23 PolarHBondContact O-N 3.31Å; T20-V24 WeakPolarHBondContact O-CG2 3.43Å; T20-V24 PolarHBondContact O-N 3.33Å
21	A	85.1	Confident	82.3	Confident	48 Å²	48	69.4 Å²	69.4	40%	0.397	43%	0.427	S	S	.	.	H	α-helix	trans	-62	-47.9	175.5	0	0	0	0	0	112.3	Y17 A18 A23 V24 K25	Y17-A21 VanDerWaalsContact O-CB 3.28Å; Y17-A21 WeakPolarHBondContact O-CB 3.25Å; Y17-A21 PolarHBondContact O-N 2.87Å; A18-A21 PolarHBondContact O-N 2.9Å; A21-A23 VanDerWaalsContact C-N 3.34Å; A21-A23 PolarHBondContact O-N 3.38Å; A21-V24 PolarHBondContact O-N 3.19Å; A21-K25 VanDerWaalsContact O-CG 3.29Å; A21-K25 WeakPolarHBondContact O-CG 3.46Å; A21-K25 PolarHBondContact O-N 3.41Å
22	S	87.7	Confident	83.9	Confident	39 Å²	39	68.5 Å²	68.5	27%	0.273	42%	0.418	S	S	.	.	H	α-helix	trans	-63.7	-38	177.9	61.5	0	0	0	0	112.3	A18 S19 K25 L26	A18-S22 PolarHBondContact O-N 2.83Å; A18-S22 PolarHBondContact O-OG 3.41Å; S19-S22 PolarHBondContact O-OG 3Å; S19-S22 VanDerWaalsContact O-OG 3.09Å; S22-K25 WeakPolarHBondContact O-CB 3.48Å; S22-K25 PolarHBondContact O-N 3.14Å; S22-L26 WeakPolarHBondContact O-CB 3.47Å; S22-L26 WeakPolarHBondContact O-CG 3.44Å; S22-L26 PolarHBondContact O-N 3.44Å
23	A	91.1	Very high	85.5	Confident	54 Å²	54	67.6 Å²	67.6	45%	0.446	40%	0.404	S	S	.	.	H	α-helix	trans	-61.9	-43.4	174.4	0	0	0	0	0	112.5	S19 T20 A21 L26 A27	S19-A23 WeakPolarHBondContact O-CB 3.5Å; S19-A23 PolarHBondContact O-N 2.89Å; S19-A23 VanDerWaalsContact O-N 3.17Å; T20-A23 PolarHBondContact O-N 3.31Å; A21-A23 VanDerWaalsContact C-N 3.34Å; A21-A23 PolarHBondContact O-N 3.38Å; A23-L26 PolarHBondContact O-N 3.48Å; A23-A27 WeakPolarHBondContact O-CB 3.34Å; A23-A27 PolarHBondContact O-N 2.96Å
24	V	91.8	Very high	87	Confident	101 Å²	101	66.5 Å²	66.5	61%	0.612	40%	0.401	S	S	*	.	H	α-helix	trans	-64.3	-41.4	176	171.3	0	0	0	0	111.2	T20 A21 A27 S28	T20-V24 WeakPolarHBondContact O-CG2 3.43Å; T20-V24 PolarHBondContact O-N 3.33Å; A21-V24 PolarHBondContact O-N 3.19Å; V24-A27 PolarHBondContact O-N 3.09Å; V24-S28 VanDerWaalsContact O-CB 3.32Å; V24-S28 WeakPolarHBondContact O-CB 3.01Å; V24-S28 PolarHBondContact O-N 3.07Å; V24-S28 PolarHBondContact O-OG 3.07Å
25	K	91.5	Very high	88.4	Confident	36 Å²	36	63.3 Å²	63.3	16%	0.157	39%	0.392	C	S	.	.	H	α-helix	trans	-60.8	-47.8	175.5	-73.6	-177	172.4	-162.5	0	112	A21 S22 S28 L29 I83 E172 W327	A21-K25 VanDerWaalsContact O-CG 3.29Å; A21-K25 WeakPolarHBondContact O-CG 3.46Å; A21-K25 PolarHBondContact O-N 3.41Å; S22-K25 WeakPolarHBondContact O-CB 3.48Å; S22-K25 PolarHBondContact O-N 3.14Å; K25-S28 PolarHBondContact O-N 3.09Å; K25-S28 PolarHBondContact O-OG 3.23Å; K25-L29 VanDerWaalsContact O-CB 3.3Å; K25-L29 WeakPolarHBondContact O-CB 3.29Å; K25-L29 PolarHBondContact O-N 3.43Å; K25-I83 HydrophobicContact CB-CD1 4.31Å; K25-I83 HydrophobicContact CB-CG2 4.11Å; K25-E172 VanDerWaalsContact CD-OE2 3.31Å; K25-E172 WeakPolarHBondContact CD-OE2 3.49Å; K25-E172 IonicContact NZ-OE1 2.82Å; K25-E172 PolarHBondContact NZ-OE1 3.47Å; K25-E172 IonicContact NZ-OE2 3.33Å; K25-E172 PolarHBondContact NZ-OE2 3.2Å; K25-W327 HydrophobicContact CB-CH2 4.36Å; K25-W327 HydrophobicContact CB-CZ2 3.68Å; K25-W327 HydrophobicContact CD-CH2 3.8Å; K25-W327 HydrophobicContact CD-CZ2 3.91Å; K25-W327 HydrophobicContact CG-CH2 3.9Å; K25-W327 HydrophobicContact CG-CZ2 3.47Å; K25-W327 VanDerWaalsContact CG-CZ2 3.47Å
26	L	94	Very high	89.6	Confident	52 Å²	52	56.9 Å²	56.9	27%	0.272	36%	0.363	S	S	.	.	H	α-helix	trans	-62.3	-45.5	176.7	-72.7	171.9	0	0	0	112.3	S22 A23 G30 M80 I83	S22-L26 WeakPolarHBondContact O-CB 3.47Å; S22-L26 WeakPolarHBondContact O-CG 3.44Å; S22-L26 PolarHBondContact O-N 3.44Å; A23-L26 PolarHBondContact O-N 3.48Å; L26-G30 PolarHBondContact O-N 3.5Å; L26-M80 HydrophobicContact CD2-CB 4.09Å; L26-M80 HydrophobicContact CD2-CE 4.42Å; L26-M80 HydrophobicContact CD2-CG 4.47Å; L26-M80 VanDerWaalsContact CD2-O 3.28Å; L26-M80 WeakPolarHBondContact CD2-O 3.29Å; L26-I83 HydrophobicContact CD1-CG2 4.46Å; L26-I83 HydrophobicContact CD2-CB 3.9Å; L26-I83 HydrophobicContact CD2-CG2 3.92Å; L26-I83 HydrophobicContact CG-CB 4.34Å; L26-I83 HydrophobicContact CG-CG2 3.77Å
27	A	95.1	Very high	90.8	Very high	60 Å²	60	55.8 Å²	55.8	50%	0.496	35%	0.351	S	S	.	.	H	α-helix	trans	-63.9	-46.7	179.1	0	0	0	0	0	111.6	A23 V24 G30 L31	A23-A27 WeakPolarHBondContact O-CB 3.34Å; A23-A27 PolarHBondContact O-N 2.96Å; V24-A27 PolarHBondContact O-N 3.09Å; A27-G30 PolarHBondContact O-N 3.49Å; A27-L31 WeakPolarHBondContact O-CG 3.35Å; A27-L31 PolarHBondContact O-N 3.11Å
28	S	94.9	Very high	91.9	Very high	35 Å²	35	53.7 Å²	53.7	25%	0.245	35%	0.351	C	S	.	.	H	α-helix	trans	-64.9	-44.7	179.1	57	0	0	0	0	112.5	V24 K25 L31 I32 W327	V24-S28 VanDerWaalsContact O-CB 3.32Å; V24-S28 WeakPolarHBondContact O-CB 3.01Å; V24-S28 PolarHBondContact O-N 3.07Å; V24-S28 PolarHBondContact O-OG 3.07Å; K25-S28 PolarHBondContact O-N 3.09Å; K25-S28 PolarHBondContact O-OG 3.23Å; S28-L31 PolarHBondContact O-N 3.28Å; S28-I32 WeakPolarHBondContact O-CG1 3.33Å; S28-I32 PolarHBondContact O-N 3.05Å; S28-W327 PolarHBondContact OG-NE1 3.48Å
29	L	94.5	Very high	92.8	Very high	0 Å²	0	51.6 Å²	51.6	0%	0	34%	0.335	C	S	.	.	H	α-helix	trans	-66.2	-38.4	176.4	-175.9	58	0	0	0	111.8	K25 L31 I32 M33 F76 V79 M80 I83 F330	K25-L29 VanDerWaalsContact O-CB 3.3Å; K25-L29 WeakPolarHBondContact O-CB 3.29Å; K25-L29 PolarHBondContact O-N 3.43Å; L29-L31 PolarHBondContact O-N 3.05Å; L29-I32 PolarHBondContact O-N 3.37Å; L29-M33 WeakPolarHBondContact O-CB 3.35Å; L29-M33 PolarHBondContact O-N 3.43Å; L29-F76 HydrophobicContact CD1-CG 4.38Å; L29-V79 HydrophobicContact CD2-CB 3.97Å; L29-V79 HydrophobicContact CD2-CG1 3.62Å; L29-M80 HydrophobicContact CB-CG 4.35Å; L29-M80 HydrophobicContact CD2-CB 4.45Å; L29-M80 HydrophobicContact CD2-CG 3.46Å; L29-M80 VanDerWaalsContact CD2-CG 3.46Å; L29-M80 HydrophobicContact CG-CG 3.8Å; L29-M80 HydrophobicContact CG-SD 4.49Å; L29-I83 HydrophobicContact CD2-CD1 4.01Å; L29-F330 HydrophobicContact CD1-CB 4.45Å; L29-F330 HydrophobicContact CD1-CD2 3.83Å; L29-F330 HydrophobicContact CD1-CE2 4.35Å; L29-F330 HydrophobicContact CD1-CG 4.29Å
30	G	96	Very high	93.6	Very high	22 Å²	22	48 Å²	48	23%	0.227	31%	0.31	C	S	.	.	H	α-helix	trans	-61.1	-41	173.7	0	0	0	0	0	112.7	L26 A27 M33 G34	L26-G30 PolarHBondContact O-N 3.5Å; A27-G30 PolarHBondContact O-N 3.49Å; G30-M33 PolarHBondContact O-N 3.18Å; G30-G34 PolarHBondContact O-N 3.42Å
31	L	95.9	Very high	94.1	Very high	131 Å²	131	46.2 Å²	46.2	69%	0.686	30%	0.302	S	S	*	.	H	α-helix	trans	-64.8	-43.6	173.6	-72.5	172.5	0	0	0	112	A27 S28 L29 G34 A35	A27-L31 WeakPolarHBondContact O-CG 3.35Å; A27-L31 PolarHBondContact O-N 3.11Å; S28-L31 PolarHBondContact O-N 3.28Å; L29-L31 PolarHBondContact O-N 3.05Å; L31-G34 PolarHBondContact O-N 2.88Å; L31-A35 VanDerWaalsContact O-CB 3.27Å; L31-A35 WeakPolarHBondContact O-CB 3.47Å; L31-A35 PolarHBondContact O-N 3.44Å
32	I	95.8	Very high	94.4	Very high	31 Å²	31	45.7 Å²	45.7	16%	0.159	30%	0.296	C	S	.	.	H	α-helix	trans	-61	-46.6	176	-69.1	167	0	0	0	110.4	S28 L29 A35 S36 F76 F330 A331	S28-I32 WeakPolarHBondContact O-CG1 3.33Å; S28-I32 PolarHBondContact O-N 3.05Å; L29-I32 PolarHBondContact O-N 3.37Å; I32-A35 PolarHBondContact O-N 3.23Å; I32-S36 WeakPolarHBondContact O-CB 3.2Å; I32-S36 PolarHBondContact O-N 2.99Å; I32-F76 HydrophobicContact CG2-CE2 4.03Å; I32-F330 HydrophobicContact CG2-CB 4.33Å; I32-A331 HydrophobicContact CD1-CB 4.48Å
33	M	96.3	Very high	94.8	Very high	42 Å²	42	43.8 Å²	43.8	21%	0.207	28%	0.283	C	S	.	.	H	α-helix	trans	-60.2	-49.8	178	-177.2	-179.9	66.9	0	0	111.2	L29 G30 S36 L37 F76 P77 M80	L29-M33 WeakPolarHBondContact O-CB 3.35Å; L29-M33 PolarHBondContact O-N 3.43Å; G30-M33 PolarHBondContact O-N 3.18Å; M33-S36 PolarHBondContact O-N 3.34Å; M33-L37 HydrophobicContact CG-CD1 3.84Å; M33-L37 HydrophobicContact CG-CG 4.41Å; M33-L37 WeakPolarHBondContact O-CB 3.49Å; M33-L37 VanDerWaalsContact O-CG 3.32Å; M33-L37 WeakPolarHBondContact O-CG 3.37Å; M33-L37 PolarHBondContact O-N 2.87Å; M33-F76 HydrophobicContact CB-CB 4.43Å; M33-F76 HydrophobicContact CB-CD2 3.91Å; M33-F76 HydrophobicContact CG-CB 4.28Å; M33-F76 HydrophobicContact CG-CD2 4.16Å; M33-F76 HydrophobicContact SD-CB 4.19Å; M33-P77 HydrophobicContact SD-CG 3.97Å; M33-M80 HydrophobicContact CE-SD 3.83Å; M33-M80 HydrophobicContact SD-SD 4.16Å
34	G	96.3	Very high	95	Very high	26 Å²	26	41.5 Å²	41.5	27%	0.268	26%	0.263	S	S	.	.	H	α-helix	trans	-60.6	-48	178.6	0	0	0	0	0	112.4	G30 L31 S36 L37 L38	G30-G34 PolarHBondContact O-N 3.42Å; L31-G34 PolarHBondContact O-N 2.88Å; G34-S36 PolarHBondContact O-N 2.87Å; G34-L37 PolarHBondContact O-N 3.21Å; G34-L38 VanDerWaalsContact O-CB 3.3Å; G34-L38 WeakPolarHBondContact O-CB 3.26Å; G34-L38 VanDerWaalsContact O-CG 3.24Å; G34-L38 WeakPolarHBondContact O-CG 3.33Å; G34-L38 PolarHBondContact O-N 3.2Å
35	A	95.6	Very high	95	Very high	59 Å²	59	42.3 Å²	42.3	49%	0.488	26%	0.264	S	S	.	.	H	α-helix	trans	-62.4	-42.3	178	0	0	0	0	0	112.2	L31 I32 G39	L31-A35 VanDerWaalsContact O-CB 3.27Å; L31-A35 WeakPolarHBondContact O-CB 3.47Å; L31-A35 PolarHBondContact O-N 3.44Å; I32-A35 PolarHBondContact O-N 3.23Å; A35-G39 PolarHBondContact O-N 3.43Å
36	S	95.9	Very high	95.1	Very high	0 Å²	0	41 Å²	41	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-64.1	-49.9	177.6	179.7	0	0	0	0	112.1	I32 M33 G34 N40 S72 A333	I32-S36 WeakPolarHBondContact O-CB 3.2Å; I32-S36 PolarHBondContact O-N 2.99Å; M33-S36 PolarHBondContact O-N 3.34Å; G34-S36 PolarHBondContact O-N 2.87Å; S36-N40 VanDerWaalsContact O-CB 3.29Å; S36-N40 WeakPolarHBondContact O-CB 3.45Å; S36-N40 PolarHBondContact O-N 3.18Å; S36-N40 PolarHBondContact O-ND2 3.49Å; S36-N40 PolarHBondContact OG-ND2 2.88Å; S36-S72 WeakPolarHBondContact CB-OG 3.19Å; S36-S72 PolarHBondContact OG-OG 3.37Å; S36-A333 WeakPolarHBondContact OG-CB 3.35Å; S36-A333 PolarHBondContact OG-O 3.25Å
37	L	96.7	Very high	95	Very high	50 Å²	50	38.8 Å²	38.8	26%	0.262	25%	0.247	S	C	.	.	H	α-helix	trans	-63	-50.5	-179.4	-73.1	173.3	0	0	0	111.1	M33 G34 A41 V69 A73	M33-L37 HydrophobicContact CG-CD1 3.84Å; M33-L37 HydrophobicContact CG-CG 4.41Å; M33-L37 WeakPolarHBondContact O-CB 3.49Å; M33-L37 VanDerWaalsContact O-CG 3.32Å; M33-L37 WeakPolarHBondContact O-CG 3.37Å; M33-L37 PolarHBondContact O-N 2.87Å; G34-L37 PolarHBondContact O-N 3.21Å; L37-A41 WeakPolarHBondContact O-CB 3.29Å; L37-A41 PolarHBondContact O-N 3.29Å; L37-V69 HydrophobicContact CD2-CG1 4.19Å; L37-A73 HydrophobicContact CD2-CB 4.02Å
38	L	95.4	Very high	94.9	Very high	130 Å²	130	40.7 Å²	40.7	68%	0.681	25%	0.248	S	C	*	.	H	α-helix	trans	-63.1	-46.1	-179.9	-68.6	173.6	0	0	0	111.4	G34 S42	G34-L38 VanDerWaalsContact O-CB 3.3Å; G34-L38 WeakPolarHBondContact O-CB 3.26Å; G34-L38 VanDerWaalsContact O-CG 3.24Å; G34-L38 WeakPolarHBondContact O-CG 3.33Å; G34-L38 PolarHBondContact O-N 3.2Å; L38-S42 VanDerWaalsContact O-CB 3.22Å; L38-S42 WeakPolarHBondContact O-CB 3.37Å; L38-S42 PolarHBondContact O-N 3.06Å; L38-S42 PolarHBondContact O-OG 3.34Å
39	G	94.7	Very high	94.7	Very high	15 Å²	15	45.6 Å²	45.6	16%	0.155	27%	0.265	C	S	.	.	H	α-helix	trans	-65.2	-50.9	-178.6	0	0	0	0	0	112.7	A35 S42 L43 P337	A35-G39 PolarHBondContact O-N 3.43Å; G39-S42 PolarHBondContact O-OG 2.9Å; G39-L43 WeakPolarHBondContact O-CB 3.33Å; G39-L43 PolarHBondContact O-N 3.28Å; G39-P337 WeakPolarHBondContact O-CG 3.29Å
40	N	96.3	Very high	94.4	Very high	0 Å²	0	46.9 Å²	46.9	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-72.9	-37.2	-177.4	-71	-67.7	0	0	0	111.6	S36 S44 C65 V69 A333 P337	S36-N40 VanDerWaalsContact O-CB 3.29Å; S36-N40 WeakPolarHBondContact O-CB 3.45Å; S36-N40 PolarHBondContact O-N 3.18Å; S36-N40 PolarHBondContact O-ND2 3.49Å; S36-N40 PolarHBondContact OG-ND2 2.88Å; N40-S44 VanDerWaalsContact O-CB 3.31Å; N40-S44 WeakPolarHBondContact O-CB 3.27Å; N40-S44 PolarHBondContact O-N 3.32Å; N40-S44 PolarHBondContact O-OG 2.9Å; N40-C65 HydrophobicContact CB-CB 4.12Å; N40-C65 PolarHBondContact OD1-SG 3.27Å; N40-C65 VanDerWaalsContact OD1-SG 3.35Å; N40-V69 HydrophobicContact CB-CG2 3.58Å; N40-A333 PolarHBondContact ND2-O 3.34Å; N40-P337 HydrophobicContact CB-CG 4.25Å; N40-P337 WeakPolarHBondContact OD1-CD 3.18Å; N40-P337 VanDerWaalsContact OD1-CG 3.23Å; N40-P337 WeakPolarHBondContact OD1-CG 3.37Å
41	A	95.2	Very high	93.9	Very high	39 Å²	39	50.2 Å²	50.2	32%	0.322	29%	0.292	S	S	.	.	H	α-helix	trans	-65.4	-44.7	175.5	0	0	0	0	0	111.8	L37 L43 S44 L45 V69	L37-A41 WeakPolarHBondContact O-CB 3.29Å; L37-A41 PolarHBondContact O-N 3.29Å; A41-L43 PolarHBondContact O-N 3Å; A41-S44 PolarHBondContact O-N 3.42Å; A41-L45 WeakPolarHBondContact O-CB 3.31Å; A41-L45 VanDerWaalsContact O-CG 3.26Å; A41-L45 WeakPolarHBondContact O-CG 3.35Å; A41-L45 PolarHBondContact O-N 3.48Å; A41-V69 HydrophobicContact CB-CG2 4.41Å
42	S	92.7	Very high	93.3	Very high	37 Å²	37	46.4 Å²	46.4	26%	0.259	28%	0.276	S	S	.	.	H	α-helix	trans	-64.4	-40	178	55.3	0	0	0	0	112.6	L38 G39 L46	L38-S42 VanDerWaalsContact O-CB 3.22Å; L38-S42 WeakPolarHBondContact O-CB 3.37Å; L38-S42 PolarHBondContact O-N 3.06Å; L38-S42 PolarHBondContact O-OG 3.34Å; G39-S42 PolarHBondContact O-OG 2.9Å; S42-L46 WeakPolarHBondContact O-CB 3.35Å; S42-L46 PolarHBondContact O-N 3.06Å
43	L	94.4	Very high	92.8	Very high	0 Å²	0	45.1 Å²	45.1	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-64.9	-46.1	173.4	-179.5	54.3	0	0	0	111.6	G39 A41 L45 L46 L47 L61 C65 P337 F341 L347	G39-L43 WeakPolarHBondContact O-CB 3.33Å; G39-L43 PolarHBondContact O-N 3.28Å; A41-L43 PolarHBondContact O-N 3Å; L43-L45 PolarHBondContact O-N 3.38Å; L43-L46 WeakPolarHBondContact O-CB 3.3Å; L43-L46 PolarHBondContact O-N 3.45Å; L43-L47 HydrophobicContact CD1-CD1 4.29Å; L43-L47 HydrophobicContact CD1-CD2 4.47Å; L43-L47 HydrophobicContact CD1-CG 4.15Å; L43-L47 HydrophobicContact CG-CD1 4.25Å; L43-L47 VanDerWaalsContact O-CG 3.31Å; L43-L47 WeakPolarHBondContact O-CG 3.49Å; L43-L47 PolarHBondContact O-N 2.96Å; L43-L61 HydrophobicContact CD2-CD1 4.48Å; L43-L61 HydrophobicContact CD2-CD2 4.19Å; L43-L61 HydrophobicContact CD2-CG 4.27Å; L43-C65 VanDerWaalsContact CD2-SG 3.56Å; L43-P337 HydrophobicContact CB-CB 4.48Å; L43-P337 HydrophobicContact CD2-CB 4.22Å; L43-P337 HydrophobicContact CD2-CG 4.46Å; L43-F341 HydrophobicContact CB-CE2 4.42Å; L43-F341 HydrophobicContact CB-CZ 4.09Å; L43-F341 HydrophobicContact CD1-CE1 4.17Å; L43-F341 HydrophobicContact CD1-CZ 4.03Å; L43-L347 HydrophobicContact CD1-CD1 4.12Å
44	S	95.1	Very high	92.4	Very high	5 Å²	5	47.2 Å²	47.2	4%	0.035	28%	0.279	C	S	.	.	H	α-helix	trans	-58.1	-45	175.9	-67.6	0	0	0	0	112.3	N40 A41 L46 L47 L48 C65	N40-S44 VanDerWaalsContact O-CB 3.31Å; N40-S44 WeakPolarHBondContact O-CB 3.27Å; N40-S44 PolarHBondContact O-N 3.32Å; N40-S44 PolarHBondContact O-OG 2.9Å; A41-S44 PolarHBondContact O-N 3.42Å; S44-L46 VanDerWaalsContact C-N 3.33Å; S44-L46 PolarHBondContact O-N 3.26Å; S44-L47 PolarHBondContact O-N 3.04Å; S44-L48 WeakPolarHBondContact O-CB 3.43Å; S44-L48 VanDerWaalsContact O-CG 3.3Å; S44-L48 WeakPolarHBondContact O-CG 3.45Å; S44-L48 PolarHBondContact O-N 3.5Å; S44-C65 WeakPolarHBondContact OG-CB 3.32Å
45	L	93.4	Very high	92.1	Very high	119 Å²	119	51.3 Å²	51.3	62%	0.623	29%	0.289	S	S	*	.	H	α-helix	trans	-61.4	-40.7	176.6	-72.5	172.9	0	0	0	112.2	A41 L43 L48 K49	A41-L45 WeakPolarHBondContact O-CB 3.31Å; A41-L45 VanDerWaalsContact O-CG 3.26Å; A41-L45 WeakPolarHBondContact O-CG 3.35Å; A41-L45 PolarHBondContact O-N 3.48Å; L43-L45 PolarHBondContact O-N 3.38Å; L45-L48 PolarHBondContact O-N 3.36Å; L45-K49 VanDerWaalsContact O-CB 3.25Å; L45-K49 WeakPolarHBondContact O-CB 3.44Å; L45-K49 PolarHBondContact O-N 3.01Å
46	L	92.4	Very high	91.8	Very high	7 Å²	7	49 Å²	49	4%	0.037	27%	0.27	C	S	.	.	H	α-helix	trans	-61.7	-45.8	175.8	179.2	65.7	0	0	0	111.5	S42 L43 S44 L48 K49 D50 L53 F341 L347 R350 L351	S42-L46 WeakPolarHBondContact O-CB 3.35Å; S42-L46 PolarHBondContact O-N 3.06Å; L43-L46 WeakPolarHBondContact O-CB 3.3Å; L43-L46 PolarHBondContact O-N 3.45Å; S44-L46 VanDerWaalsContact C-N 3.33Å; S44-L46 PolarHBondContact O-N 3.26Å; L46-L48 VanDerWaalsContact C-N 3.32Å; L46-L48 PolarHBondContact O-N 3.07Å; L46-K49 PolarHBondContact O-N 3.46Å; L46-D50 PolarHBondContact O-N 3.4Å; L46-D50 VanDerWaalsContact O-N 3.1Å; L46-L53 HydrophobicContact CG-CD1 4.33Å; L46-F341 HydrophobicContact CD2-CE1 4.17Å; L46-L347 HydrophobicContact CD2-CB 4.35Å; L46-L347 HydrophobicContact CD2-CD2 4.07Å; L46-R350 HydrophobicContact CD1-CB 3.86Å; L46-L351 HydrophobicContact CD2-CB 4.11Å; L46-L351 HydrophobicContact CD2-CD1 4.23Å
47	L	93.3	Very high	91.5	Very high	6 Å²	6	49 Å²	49	3%	0.031	27%	0.27	C	S	.	.	H	α-helix	trans	-67.1	-32.2	-179.4	-65.7	178.2	0	0	0	112.8	L43 S44 L53 Y58 L61 L62 L347	L43-L47 HydrophobicContact CD1-CD1 4.29Å; L43-L47 HydrophobicContact CD1-CD2 4.47Å; L43-L47 HydrophobicContact CD1-CG 4.15Å; L43-L47 HydrophobicContact CG-CD1 4.25Å; L43-L47 VanDerWaalsContact O-CG 3.31Å; L43-L47 WeakPolarHBondContact O-CG 3.49Å; L43-L47 PolarHBondContact O-N 2.96Å; S44-L47 PolarHBondContact O-N 3.04Å; L47-L53 HydrophobicContact CD2-CB 4.39Å; L47-L53 HydrophobicContact CD2-CD1 4.02Å; L47-Y58 HydrophobicContact CD2-CD1 3.82Å; L47-Y58 HydrophobicContact CD2-CG 4.24Å; L47-L61 HydrophobicContact CD1-CB 3.99Å; L47-L61 HydrophobicContact CD1-CD2 4.06Å; L47-L61 HydrophobicContact CD1-CG 3.95Å; L47-L62 HydrophobicContact CB-CD1 4.39Å; L47-L62 HydrophobicContact CD1-CB 4.04Å; L47-L347 HydrophobicContact CD2-CD2 4.05Å
48	L	92.4	Very high	91.4	Very high	101 Å²	101	47.2 Å²	47.2	53%	0.529	26%	0.26	S	S	.	.	H	α-helix	trans	-77.5	-34.1	176.7	-72.1	171.3	0	0	0	113	S44 L45 L46 L62	S44-L48 WeakPolarHBondContact O-CB 3.43Å; S44-L48 VanDerWaalsContact O-CG 3.3Å; S44-L48 WeakPolarHBondContact O-CG 3.45Å; S44-L48 PolarHBondContact O-N 3.5Å; L45-L48 PolarHBondContact O-N 3.36Å; L46-L48 VanDerWaalsContact C-N 3.32Å; L46-L48 PolarHBondContact O-N 3.07Å; L48-L62 HydrophobicContact CD1-CD1 4.46Å; L48-L62 HydrophobicContact CD2-CD1 4.39Å; L48-L62 HydrophobicContact CD2-CD2 3.69Å; L48-L62 HydrophobicContact CG-CD1 4.07Å; L48-L62 HydrophobicContact CG-CD2 4.24Å
49	K	89.9	Confident	91.3	Very high	137 Å²	137	43.6 Å²	43.6	60%	0.596	24%	0.237	S	C	*	.	H	α-helix	trans	-82.5	-36.4	-175.1	-173.3	171.2	178	176.5	0	112.6	L45 L46 S51	L45-K49 VanDerWaalsContact O-CB 3.25Å; L45-K49 WeakPolarHBondContact O-CB 3.44Å; L45-K49 PolarHBondContact O-N 3.01Å; L46-K49 PolarHBondContact O-N 3.46Å; K49-S51 PolarHBondContact O-N 2.95Å
50	D	88.3	Confident	91.4	Very high	27 Å²	27	42.9 Å²	42.9	14%	0.144	23%	0.23	C	C	.	.			trans	-92.2	103	-175.7	-166.9	-20.9	0	0	0	111.9	L46 S52 L53 R350	L46-D50 PolarHBondContact O-N 3.4Å; L46-D50 VanDerWaalsContact O-N 3.1Å; D50-S52 PolarHBondContact O-N 2.93Å; D50-S52 VanDerWaalsContact O-N 3.16Å; D50-S52 VanDerWaalsContact OD1-CB 3.23Å; D50-S52 WeakPolarHBondContact OD1-CB 3.4Å; D50-S52 PolarHBondContact OD1-N 3.19Å; D50-S52 PolarHBondContact OD1-OG 3.04Å; D50-S52 PolarHBondContact OD2-OG 2.9Å; D50-L53 HydrophobicContact CB-CD1 3.96Å; D50-L53 HydrophobicContact CB-CG 4.12Å; D50-L53 WeakPolarHBondContact O-CB 3.4Å; D50-L53 PolarHBondContact O-N 3.09Å; D50-R350 WeakPolarHBondContact OD2-CD 3.36Å; D50-R350 WeakPolarHBondContact OD2-CG 3.34Å; D50-R350 IonicContact OD2-NE 3.63Å
51	S	86.4	Confident	91.4	Very high	93 Å²	93	42.9 Å²	42.9	65%	0.65	23%	0.23	S	C	*	.	G	3₁₀ helix	trans	-63.2	-20.3	178.6	62.7	0	0	0	0	113.9	K49 L53 H54	K49-S51 PolarHBondContact O-N 2.95Å; S51-L53 PolarHBondContact O-N 3.05Å; S51-H54 WeakPolarHBondContact O-CB 3.43Å; S51-H54 PolarHBondContact O-N 3.47Å
52	S	82.9	Confident	91.4	Very high	50 Å²	50	42.2 Å²	42.2	35%	0.35	22%	0.221	S	C	.	.	G	3₁₀ helix	trans	-70.3	-20.7	175.7	75.9	0	0	0	0	112.8	D50	D50-S52 PolarHBondContact O-N 2.93Å; D50-S52 VanDerWaalsContact O-N 3.16Å; D50-S52 VanDerWaalsContact OD1-CB 3.23Å; D50-S52 WeakPolarHBondContact OD1-CB 3.4Å; D50-S52 PolarHBondContact OD1-N 3.19Å; D50-S52 PolarHBondContact OD1-OG 3.04Å; D50-S52 PolarHBondContact OD2-OG 2.9Å
53	L	85.9	Confident	91.7	Very high	5 Å²	5	41.2 Å²	41.2	3%	0.026	21%	0.213	C	C	.	.	G	3₁₀ helix	trans	-91.2	-0	176.5	-59.8	177.5	0	0	0	112.8	L46 L47 D50 S51 K55 Y58 E346 L347	L46-L53 HydrophobicContact CG-CD1 4.33Å; L47-L53 HydrophobicContact CD2-CB 4.39Å; L47-L53 HydrophobicContact CD2-CD1 4.02Å; D50-L53 HydrophobicContact CB-CD1 3.96Å; D50-L53 HydrophobicContact CB-CG 4.12Å; D50-L53 WeakPolarHBondContact O-CB 3.4Å; D50-L53 PolarHBondContact O-N 3.09Å; S51-L53 PolarHBondContact O-N 3.05Å; L53-K55 PolarHBondContact O-N 3.32Å; L53-Y58 HydrophobicContact CB-CD2 4.28Å; L53-Y58 HydrophobicContact CB-CG 4.4Å; L53-Y58 HydrophobicContact CD2-CD2 4.46Å; L53-Y58 HydrophobicContact CD2-CE1 4.38Å; L53-Y58 HydrophobicContact CD2-CE2 4.01Å; L53-Y58 WeakPolarHBondContact O-CB 3.38Å; L53-Y58 WeakPolarHBondContact O-CD2 3.26Å; L53-E346 HydrophobicContact CD2-CG 4.25Å; L53-L347 HydrophobicContact CD1-CD2 3.6Å; L53-L347 HydrophobicContact CD2-CD2 4.25Å
54	H	87.6	Confident	91.7	Very high	86 Å²	86	41.4 Å²	41.4	40%	0.398	21%	0.214	S	C	.	.			trans	-71.7	70.5	176.4	-69.7	171.7	0	0	0	112.2	S51 Y59	S51-H54 WeakPolarHBondContact O-CB 3.43Å; S51-H54 PolarHBondContact O-N 3.47Å; H54-Y59 HydrophobicContact CB-CE1 4.48Å; H54-Y59 WeakPolarHBondContact CB-OH 3.44Å
55	K	88.6	Confident	91.8	Very high	112 Å²	112	41.1 Å²	41.1	49%	0.487	21%	0.212	S	C	.	.	S	Bend	trans	-128.8	153.9	176.8	-52.1	-179.5	-179.9	179.2	0	109.3	L53 P57 Y58 Y59	L53-K55 PolarHBondContact O-N 3.32Å; K55-P57 VanDerWaalsContact C-CD 3.45Å; K55-P57 HydrophobicContact CB-CG 4.3Å; K55-P57 VanDerWaalsContact O-N 3.16Å; K55-Y58 HydrophobicContact CB-CD2 4.01Å; K55-Y58 HydrophobicContact CD-CE2 4.49Å; K55-Y58 HydrophobicContact CG-CD2 4.5Å; K55-Y58 PolarHBondContact O-N 3.5Å; K55-Y59 PolarHBondContact O-N 2.94Å
56	A	89.6	Confident	92	Very high	10 Å²	10	39.5 Å²	39.5	8%	0.083	20%	0.203	C	C	.	.	H	α-helix	trans	-42.6	-49.2	179.1	0	0	0	0	0	115.9	Y58 Y59 F60 M135 C140	A56-Y58 PolarHBondContact O-N 3.34Å; A56-Y59 PolarHBondContact O-N 3.46Å; A56-F60 VanDerWaalsContact O-CD2 3.25Å; A56-F60 WeakPolarHBondContact O-CD2 3.44Å; A56-F60 PolarHBondContact O-N 3.14Å; A56-M135 HydrophobicContact CB-CB 4.3Å; A56-C140 VanDerWaalsContact CB-SG 3.54Å
57	P	90.8	Very high	92.2	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-60.9	-31.2	178.2	21.5	-32.2	0	0	0	113	K55 L61 Y131 I284 Y288	K55-P57 VanDerWaalsContact C-CD 3.45Å; K55-P57 HydrophobicContact CB-CG 4.3Å; K55-P57 VanDerWaalsContact O-N 3.16Å; P57-L61 PolarHBondContact O-N 2.89Å; P57-Y131 WeakPolarHBondContact CD-OH 3.08Å; P57-I284 HydrophobicContact CB-CG2 3.71Å; P57-I284 HydrophobicContact CG-CD1 4.26Å; P57-I284 HydrophobicContact CG-CG2 4.26Å; P57-Y288 HydrophobicContact CB-CE2 4.02Å; P57-Y288 PolarHBondContact O-OH 2.81Å
58	Y	93.3	Very high	92.4	Very high	13 Å²	13	39.5 Å²	39.5	5%	0.051	20%	0.204	C	C	.	.	H	α-helix	trans	-82.8	-23.1	-177.3	-64.6	-66.2	0	0	0	112.6	L47 L53 K55 A56 L61 L62 I284 N344 L347	L47-Y58 HydrophobicContact CD2-CD1 3.82Å; L47-Y58 HydrophobicContact CD2-CG 4.24Å; L53-Y58 HydrophobicContact CB-CD2 4.28Å; L53-Y58 HydrophobicContact CB-CG 4.4Å; L53-Y58 HydrophobicContact CD2-CD2 4.46Å; L53-Y58 HydrophobicContact CD2-CE1 4.38Å; L53-Y58 HydrophobicContact CD2-CE2 4.01Å; L53-Y58 WeakPolarHBondContact O-CB 3.38Å; L53-Y58 WeakPolarHBondContact O-CD2 3.26Å; K55-Y58 HydrophobicContact CB-CD2 4.01Å; K55-Y58 HydrophobicContact CD-CE2 4.49Å; K55-Y58 HydrophobicContact CG-CD2 4.5Å; K55-Y58 PolarHBondContact O-N 3.5Å; A56-Y58 PolarHBondContact O-N 3.34Å; Y58-L61 HydrophobicContact CD1-CD2 4.32Å; Y58-L61 WeakPolarHBondContact O-CB 3.03Å; Y58-L61 PolarHBondContact O-N 3.17Å; Y58-L62 WeakPolarHBondContact O-CB 3.18Å; Y58-L62 PolarHBondContact O-N 2.85Å; Y58-I284 HydrophobicContact CE2-CD1 4.4Å; Y58-N344 PolarHBondContact OH-ND2 3.03Å; Y58-L347 HydrophobicContact CE1-CD2 4.19Å
59	Y	95.1	Very high	92.6	Very high	53 Å²	53	36.5 Å²	36.5	21%	0.208	19%	0.19	C	C	.	.	H	α-helix	trans	-66.2	-41	171	-62.9	-45.4	0	0	0	112.5	H54 K55 A56 L61 L62 D63 L137 C140	H54-Y59 HydrophobicContact CB-CE1 4.48Å; H54-Y59 WeakPolarHBondContact CB-OH 3.44Å; K55-Y59 PolarHBondContact O-N 2.94Å; A56-Y59 PolarHBondContact O-N 3.46Å; Y59-L61 VanDerWaalsContact C-N 3.3Å; Y59-L61 PolarHBondContact O-N 2.92Å; Y59-L62 PolarHBondContact O-N 2.92Å; Y59-D63 PolarHBondContact O-N 2.82Å; Y59-L137 HydrophobicContact CD2-CD1 4.05Å; Y59-L137 HydrophobicContact CE1-CD1 4.2Å; Y59-L137 HydrophobicContact CE2-CD1 3.64Å; Y59-C140 HydrophobicContact CD2-CB 4.18Å
60	F	96.1	Very high	92.9	Very high	1 Å²	1	33.9 Å²	33.9	0%	0.004	18%	0.182	C	C	.	.	H	α-helix	trans	-67.1	-33.2	173.2	-58.6	-54	0	0	0	112.3	A56 L62 L64 L113 V117 T120 C140 V143 I144	A56-F60 VanDerWaalsContact O-CD2 3.25Å; A56-F60 WeakPolarHBondContact O-CD2 3.44Å; A56-F60 PolarHBondContact O-N 3.14Å; F60-L62 VanDerWaalsContact C-N 3.34Å; F60-L64 WeakPolarHBondContact O-CB 3.37Å; F60-L64 PolarHBondContact O-N 3.39Å; F60-L113 HydrophobicContact CB-CD1 4.36Å; F60-L113 HydrophobicContact CD1-CD1 3.97Å; F60-V117 HydrophobicContact CB-CG2 3.61Å; F60-V117 HydrophobicContact CD2-CG2 4.2Å; F60-V117 HydrophobicContact CG-CG2 3.92Å; F60-T120 HydrophobicContact CE2-CG2 3.95Å; F60-C140 HydrophobicContact CE1-CB 4.44Å; F60-C140 HydrophobicContact CZ-CB 4.25Å; F60-V143 HydrophobicContact CE1-CB 4.06Å; F60-V143 HydrophobicContact CE1-CG1 3.74Å; F60-V143 HydrophobicContact CZ-CB 4.34Å; F60-V143 HydrophobicContact CZ-CG1 4.13Å; F60-I144 HydrophobicContact CD1-CD1 4.32Å; F60-I144 HydrophobicContact CD1-CG1 4.02Å; F60-I144 HydrophobicContact CE1-CG1 4.1Å
61	L	95.6	Very high	93.3	Very high	0 Å²	0	33.6 Å²	33.6	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-66.1	-41	174.5	-168.7	55.6	0	0	0	111.1	L43 L47 P57 Y58 Y59 L64 C65 M287 Y288 I291 L347	L43-L61 HydrophobicContact CD2-CD1 4.48Å; L43-L61 HydrophobicContact CD2-CD2 4.19Å; L43-L61 HydrophobicContact CD2-CG 4.27Å; L47-L61 HydrophobicContact CD1-CB 3.99Å; L47-L61 HydrophobicContact CD1-CD2 4.06Å; L47-L61 HydrophobicContact CD1-CG 3.95Å; P57-L61 PolarHBondContact O-N 2.89Å; Y58-L61 HydrophobicContact CD1-CD2 4.32Å; Y58-L61 WeakPolarHBondContact O-CB 3.03Å; Y58-L61 PolarHBondContact O-N 3.17Å; Y59-L61 VanDerWaalsContact C-N 3.3Å; Y59-L61 PolarHBondContact O-N 2.92Å; L61-L64 PolarHBondContact O-N 3.17Å; L61-C65 PolarHBondContact O-N 3.21Å; L61-C65 PolarHBondContact O-SG 2.95Å; L61-C65 VanDerWaalsContact O-SG 3.36Å; L61-M287 HydrophobicContact CD2-CE 4.13Å; L61-Y288 WeakPolarHBondContact CA-OH 3.35Å; L61-Y288 VanDerWaalsContact CB-OH 3.27Å; L61-Y288 WeakPolarHBondContact CB-OH 3.38Å; L61-Y288 HydrophobicContact CD1-CE1 4.46Å; L61-Y288 PolarHBondContact N-OH 2.68Å; L61-Y288 VanDerWaalsContact N-OH 3.1Å; L61-I291 HydrophobicContact CD1-CD1 4.27Å; L61-L347 HydrophobicContact CD2-CD1 4.42Å
62	L	96.3	Very high	93.7	Very high	24 Å²	24	29.2 Å²	29.2	13%	0.126	15%	0.148	C	C	.	.	H	α-helix	trans	-63	-47.8	177.6	177.8	64.6	0	0	0	111.3	L47 L48 Y58 Y59 F60 L64 C65 L66	L47-L62 HydrophobicContact CB-CD1 4.39Å; L47-L62 HydrophobicContact CD1-CB 4.04Å; L48-L62 HydrophobicContact CD1-CD1 4.46Å; L48-L62 HydrophobicContact CD2-CD1 4.39Å; L48-L62 HydrophobicContact CD2-CD2 3.69Å; L48-L62 HydrophobicContact CG-CD1 4.07Å; L48-L62 HydrophobicContact CG-CD2 4.24Å; Y58-L62 WeakPolarHBondContact O-CB 3.18Å; Y58-L62 PolarHBondContact O-N 2.85Å; Y59-L62 PolarHBondContact O-N 2.92Å; F60-L62 VanDerWaalsContact C-N 3.34Å; L62-L64 VanDerWaalsContact C-N 3.33Å; L62-L64 PolarHBondContact O-N 3.07Å; L62-C65 PolarHBondContact O-N 2.98Å; L62-L66 HydrophobicContact CD1-CD1 4.14Å; L62-L66 HydrophobicContact CD1-CG 4.16Å; L62-L66 HydrophobicContact CG-CD1 3.99Å; L62-L66 HydrophobicContact CG-CG 4.4Å; L62-L66 WeakPolarHBondContact O-CB 3.43Å; L62-L66 VanDerWaalsContact O-CG 3.28Å; L62-L66 WeakPolarHBondContact O-CG 3.37Å; L62-L66 PolarHBondContact O-N 2.96Å
63	D	97.3	Very high	94.3	Very high	17 Å²	17	29.2 Å²	29.2	9%	0.091	15%	0.151	C	C	.	.	H	α-helix	trans	-58	-45.4	175.8	-175.7	59.3	0	0	0	111.4	Y59 C65 L66 A67 H109 L113 I144 W148	Y59-D63 PolarHBondContact O-N 2.82Å; D63-C65 PolarHBondContact O-N 3.4Å; D63-L66 PolarHBondContact O-N 3.48Å; D63-A67 WeakPolarHBondContact O-CB 3.44Å; D63-A67 PolarHBondContact O-N 2.81Å; D63-H109 IonicContact OD1-CE1 3.91Å; D63-H109 IonicContact OD2-CE1 3.13Å; D63-H109 PolarHBondContact OD2-CE1 2.84Å; D63-H109 IonicContact OD2-NE2 3.25Å; D63-H109 PolarHBondContact OD2-NE2 2.96Å; D63-L113 HydrophobicContact CB-CD2 4.37Å; D63-L113 WeakPolarHBondContact OD2-CD2 3.4Å; D63-I144 HydrophobicContact CB-CD1 4.08Å; D63-I144 HydrophobicContact CB-CG1 4.3Å; D63-I144 HydrophobicContact CB-CG2 4.5Å; D63-I144 WeakPolarHBondContact OD1-CG2 3.37Å; D63-W148 PolarHBondContact OD1-NE1 3.43Å; D63-W148 VanDerWaalsContact OD1-NE1 3.14Å
64	L	96.2	Very high	94.7	Very high	3 Å²	3	31.1 Å²	31.1	2%	0.016	16%	0.163	C	C	.	.	H	α-helix	trans	-57.6	-47.2	175.6	-175.9	63	0	0	0	112.2	F60 L61 L62 A67 D68 V110 L113 I291 N336	F60-L64 WeakPolarHBondContact O-CB 3.37Å; F60-L64 PolarHBondContact O-N 3.39Å; L61-L64 PolarHBondContact O-N 3.17Å; L62-L64 VanDerWaalsContact C-N 3.33Å; L62-L64 PolarHBondContact O-N 3.07Å; L64-A67 PolarHBondContact O-N 3.38Å; L64-D68 PolarHBondContact O-N 3.49Å; L64-V110 HydrophobicContact CD1-CB 4.24Å; L64-V110 HydrophobicContact CD1-CG2 3.54Å; L64-L113 HydrophobicContact CB-CD2 3.76Å; L64-L113 HydrophobicContact CD1-CD2 4.15Å; L64-I291 HydrophobicContact CD2-CG2 4.13Å; L64-N336 HydrophobicContact CD2-CB 4.36Å; L64-N336 WeakPolarHBondContact CD2-ND2 3.48Å; L64-N336 WeakPolarHBondContact CG-ND2 3.41Å
65	C	96.8	Very high	95	Very high	0 Å²	0	27.1 Å²	27.1	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-67.5	-39	178.5	-71.9	0	0	0	0	112.7	N40 L43 S44 L61 L62 D63 D68 V69	N40-C65 HydrophobicContact CB-CB 4.12Å; N40-C65 PolarHBondContact OD1-SG 3.27Å; N40-C65 VanDerWaalsContact OD1-SG 3.35Å; L43-C65 VanDerWaalsContact CD2-SG 3.56Å; S44-C65 WeakPolarHBondContact OG-CB 3.32Å; L61-C65 PolarHBondContact O-N 3.21Å; L61-C65 PolarHBondContact O-SG 2.95Å; L61-C65 VanDerWaalsContact O-SG 3.36Å; L62-C65 PolarHBondContact O-N 2.98Å; D63-C65 PolarHBondContact O-N 3.4Å; C65-D68 PolarHBondContact O-N 3.33Å; C65-V69 WeakPolarHBondContact O-CG2 3.46Å; C65-V69 PolarHBondContact O-N 3.44Å
66	L	96.9	Very high	95.3	Very high	85 Å²	85	21.9 Å²	21.9	45%	0.445	12%	0.122	S	C	.	.	H	α-helix	trans	-65.5	-41.7	176.8	-71.2	174.5	0	0	0	111.5	L62 D63 V69 L70	L62-L66 HydrophobicContact CD1-CD1 4.14Å; L62-L66 HydrophobicContact CD1-CG 4.16Å; L62-L66 HydrophobicContact CG-CD1 3.99Å; L62-L66 HydrophobicContact CG-CG 4.4Å; L62-L66 WeakPolarHBondContact O-CB 3.43Å; L62-L66 VanDerWaalsContact O-CG 3.28Å; L62-L66 WeakPolarHBondContact O-CG 3.37Å; L62-L66 PolarHBondContact O-N 2.96Å; D63-L66 PolarHBondContact O-N 3.48Å; L66-V69 PolarHBondContact O-N 2.88Å; L66-L70 WeakPolarHBondContact O-CB 3.49Å; L66-L70 PolarHBondContact O-N 3.44Å
67	A	97.1	Very high	95.5	Very high	6 Å²	6	24 Å²	24	5%	0.05	13%	0.134	C	C	.	.	H	α-helix	trans	-62.1	-42.1	174.6	0	0	0	0	0	111.8	D63 L64 L70 R71 F106	D63-A67 WeakPolarHBondContact O-CB 3.44Å; D63-A67 PolarHBondContact O-N 2.81Å; L64-A67 PolarHBondContact O-N 3.38Å; A67-L70 PolarHBondContact O-N 3.05Å; A67-R71 WeakPolarHBondContact O-CB 3.4Å; A67-R71 PolarHBondContact O-N 3.1Å; A67-F106 HydrophobicContact CB-CD1 4.28Å
68	D	96.6	Very high	95.6	Very high	7 Å²	7	27 Å²	27	4%	0.037	15%	0.148	C	C	.	.	H	α-helix	trans	-68.9	-37.2	176.3	-83.3	-40.2	0	0	0	113.4	L64 C65 L70 R71 S72 N336	L64-D68 PolarHBondContact O-N 3.49Å; C65-D68 PolarHBondContact O-N 3.33Å; D68-L70 VanDerWaalsContact C-N 3.34Å; D68-R71 IonicContact OD1-CZ 3.57Å; D68-R71 IonicContact OD1-NE 3.47Å; D68-R71 PolarHBondContact OD1-NE 3.04Å; D68-R71 IonicContact OD1-NH2 2.77Å; D68-R71 PolarHBondContact OD1-NH2 2.99Å; D68-S72 VanDerWaalsContact O-CB 3.23Å; D68-S72 WeakPolarHBondContact O-CB 3.29Å; D68-S72 PolarHBondContact O-N 2.91Å; D68-S72 PolarHBondContact O-OG 2.96Å; D68-N336 PolarHBondContact OD2-ND2 3.43Å
69	V	97.3	Very high	95.6	Very high	37 Å²	37	26.5 Å²	26.5	22%	0.224	15%	0.146	C	C	.	.	H	α-helix	trans	-59.7	-48.4	171.2	167.3	0	0	0	0	109.5	L37 N40 A41 C65 L66 S72 A73	L37-V69 HydrophobicContact CD2-CG1 4.19Å; N40-V69 HydrophobicContact CB-CG2 3.58Å; A41-V69 HydrophobicContact CB-CG2 4.41Å; C65-V69 WeakPolarHBondContact O-CG2 3.46Å; C65-V69 PolarHBondContact O-N 3.44Å; L66-V69 PolarHBondContact O-N 2.88Å; V69-S72 PolarHBondContact O-N 3.36Å; V69-A73 WeakPolarHBondContact O-CB 3.41Å; V69-A73 PolarHBondContact O-N 3.45Å
70	L	96.4	Very high	95.5	Very high	82 Å²	82	26.1 Å²	26.1	43%	0.429	15%	0.147	S	C	.	.	H	α-helix	trans	-63.6	-44.9	-178.8	-173	59.4	0	0	0	111.5	L66 A67 D68 S72 A73 V74 F106	L66-L70 WeakPolarHBondContact O-CB 3.49Å; L66-L70 PolarHBondContact O-N 3.44Å; A67-L70 PolarHBondContact O-N 3.05Å; D68-L70 VanDerWaalsContact C-N 3.34Å; L70-S72 PolarHBondContact O-N 3.39Å; L70-A73 PolarHBondContact O-N 3.15Å; L70-V74 HydrophobicContact CD1-CG2 3.84Å; L70-V74 WeakPolarHBondContact O-CB 3.29Å; L70-V74 WeakPolarHBondContact O-CG2 3.37Å; L70-V74 PolarHBondContact O-N 2.94Å; L70-F106 HydrophobicContact CB-CE1 4.16Å; L70-F106 HydrophobicContact CB-CZ 4Å; L70-F106 HydrophobicContact CD2-CE1 3.81Å; L70-F106 HydrophobicContact CD2-CZ 3.51Å; L70-F106 HydrophobicContact CG-CE1 4.08Å; L70-F106 HydrophobicContact CG-CE2 4.44Å; L70-F106 HydrophobicContact CG-CZ 3.54Å
71	R	95.6	Very high	95.3	Very high	22 Å²	22	27.3 Å²	27.3	8%	0.083	16%	0.157	C	C	.	.	H	α-helix	trans	-60.9	-45.6	175.2	-176.1	175.7	58.8	97.4	-6.3	112.1	A67 D68 C75 F76 F106	A67-R71 WeakPolarHBondContact O-CB 3.4Å; A67-R71 PolarHBondContact O-N 3.1Å; D68-R71 IonicContact OD1-CZ 3.57Å; D68-R71 IonicContact OD1-NE 3.47Å; D68-R71 PolarHBondContact OD1-NE 3.04Å; D68-R71 IonicContact OD1-NH2 2.77Å; D68-R71 PolarHBondContact OD1-NH2 2.99Å; R71-C75 HydrophobicContact CG-CB 4.33Å; R71-C75 WeakPolarHBondContact O-CA 3.45Å; R71-C75 VanDerWaalsContact O-CB 3.23Å; R71-C75 WeakPolarHBondContact O-CB 3.36Å; R71-C75 PolarHBondContact O-N 3.16Å; R71-F76 VanDerWaalsContact NH1-CZ 3.3Å; R71-F106 HydrophobicContact CB-CB 4.23Å; R71-F106 HydrophobicContact CB-CD1 4.41Å; R71-F106 HydrophobicContact CB-CD2 3.63Å; R71-F106 HydrophobicContact CB-CE2 4.12Å; R71-F106 HydrophobicContact CB-CG 3.85Å; R71-F106 HydrophobicContact CG-CB 4.22Å; R71-F106 HydrophobicContact CG-CD2 3.84Å; R71-F106 HydrophobicContact CG-CG 4.21Å
72	S	95.9	Very high	95.1	Very high	0 Å²	0	27.3 Å²	27.3	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-70	-35.9	-178.2	-53	0	0	0	0	112	S36 D68 V69 L70 F76 P77	S36-S72 WeakPolarHBondContact CB-OG 3.19Å; S36-S72 PolarHBondContact OG-OG 3.37Å; D68-S72 VanDerWaalsContact O-CB 3.23Å; D68-S72 WeakPolarHBondContact O-CB 3.29Å; D68-S72 PolarHBondContact O-N 2.91Å; D68-S72 PolarHBondContact O-OG 2.96Å; V69-S72 PolarHBondContact O-N 3.36Å; L70-S72 PolarHBondContact O-N 3.39Å; S72-F76 WeakPolarHBondContact O-CB 3.42Å; S72-P77 WeakPolarHBondContact O-CD 3.42Å
73	A	95.7	Very high	94.8	Very high	50 Å²	50	26.4 Å²	26.4	41%	0.413	15%	0.152	S	C	.	.	H	α-helix	trans	-75.7	-31.6	179.4	0	0	0	0	0	112.8	L37 V69 L70 P77	L37-A73 HydrophobicContact CD2-CB 4.02Å; V69-A73 WeakPolarHBondContact O-CB 3.41Å; V69-A73 PolarHBondContact O-N 3.45Å; L70-A73 PolarHBondContact O-N 3.15Å; A73-P77 WeakPolarHBondContact O-CG 3.43Å
74	V	93.9	Very high	94.3	Very high	45 Å²	45	28.3 Å²	28.3	27%	0.273	18%	0.176	S	C	.	.	H	α-helix	trans	-97.9	-54.1	-176.6	-179.5	0	0	0	0	111.4	L70 F78 L102	L70-V74 HydrophobicContact CD1-CG2 3.84Å; L70-V74 WeakPolarHBondContact O-CB 3.29Å; L70-V74 WeakPolarHBondContact O-CG2 3.37Å; L70-V74 PolarHBondContact O-N 2.94Å; V74-F78 HydrophobicContact CG1-CE2 4.44Å; V74-F78 WeakPolarHBondContact O-CD2 3.3Å; V74-L102 HydrophobicContact CG1-CD1 3.81Å
75	C	93.6	Very high	93.9	Very high	3 Å²	3	30.3 Å²	30.3	2%	0.02	19%	0.193	C	C	.	.	H	α-helix	trans	-78.9	-42.2	-168.4	-54.9	0	0	0	0	112.6	R71 F78 V79	R71-C75 HydrophobicContact CG-CB 4.33Å; R71-C75 WeakPolarHBondContact O-CA 3.45Å; R71-C75 VanDerWaalsContact O-CB 3.23Å; R71-C75 WeakPolarHBondContact O-CB 3.36Å; R71-C75 PolarHBondContact O-N 3.16Å; C75-F78 PolarHBondContact O-N 3.07Å; C75-V79 PolarHBondContact O-N 3.42Å
76	F	94.8	Very high	93.3	Very high	2 Å²	2	33 Å²	33	1%	0.009	22%	0.221	C	C	.	.	H	α-helix	trans	-65.3	-39.1	-174.7	-62.6	-8.4	0	0	0	114.1	L29 I32 M33 R71 S72 F78 V79 M80 F330 A333	L29-F76 HydrophobicContact CD1-CG 4.38Å; I32-F76 HydrophobicContact CG2-CE2 4.03Å; M33-F76 HydrophobicContact CB-CB 4.43Å; M33-F76 HydrophobicContact CB-CD2 3.91Å; M33-F76 HydrophobicContact CG-CB 4.28Å; M33-F76 HydrophobicContact CG-CD2 4.16Å; M33-F76 HydrophobicContact SD-CB 4.19Å; R71-F76 VanDerWaalsContact NH1-CZ 3.3Å; S72-F76 WeakPolarHBondContact O-CB 3.42Å; F76-F78 VanDerWaalsContact C-N 3.28Å; F76-F78 PolarHBondContact O-N 3.11Å; F76-V79 PolarHBondContact O-N 3.01Å; F76-M80 WeakPolarHBondContact O-CG 3.48Å; F76-M80 PolarHBondContact O-N 3.42Å; F76-F330 HydrophobicContact CD1-CD1 4.25Å; F76-F330 HydrophobicContact CE1-CB 4.25Å; F76-F330 AromaticContact CE1-CD1 3.54Å; F76-F330 HydrophobicContact CE1-CD1 3.54Å; F76-F330 HydrophobicContact CE1-CE1 4.14Å; F76-F330 HydrophobicContact CE1-CG 4.07Å; F76-F330 HydrophobicContact CZ-CB 4.04Å; F76-F330 HydrophobicContact CZ-CD1 4.16Å; F76-F330 HydrophobicContact CZ-CG 4.37Å; F76-A333 HydrophobicContact CE2-CB 4.04Å; F76-A333 HydrophobicContact CZ-CB 3.92Å
77	P	94.6	Very high	92.7	Very high	53 Å²	53	30.6 Å²	30.6	34%	0.344	21%	0.211	S	C	.	.	H	α-helix	trans	-59.4	-36.5	174.5	-28.9	37.7	0	0	0	113.7	M33 S72 A73 M80 A81	M33-P77 HydrophobicContact SD-CG 3.97Å; S72-P77 WeakPolarHBondContact O-CD 3.42Å; A73-P77 WeakPolarHBondContact O-CG 3.43Å; P77-M80 PolarHBondContact O-N 3.18Å; P77-A81 WeakPolarHBondContact O-CB 3.46Å; P77-A81 PolarHBondContact O-N 3.01Å
78	F	93.4	Very high	92.2	Very high	63 Å²	63	35.3 Å²	35.3	28%	0.276	24%	0.235	S	C	.	.	H	α-helix	trans	-68	-38.1	176	-76.3	-69	0	0	0	112.4	V74 C75 F76 A81 S82 W89 Y91 V99	V74-F78 HydrophobicContact CG1-CE2 4.44Å; V74-F78 WeakPolarHBondContact O-CD2 3.3Å; C75-F78 PolarHBondContact O-N 3.07Å; F76-F78 VanDerWaalsContact C-N 3.28Å; F76-F78 PolarHBondContact O-N 3.11Å; F78-A81 PolarHBondContact O-N 3.28Å; F78-S82 PolarHBondContact O-N 3.43Å; F78-W89 HydrophobicContact CB-CH2 3.79Å; F78-W89 HydrophobicContact CB-CZ3 4.13Å; F78-W89 AromaticContact CD1-CH2 3.94Å; F78-W89 HydrophobicContact CD1-CH2 3.94Å; F78-W89 HydrophobicContact CD1-CZ2 4.37Å; F78-W89 HydrophobicContact CG-CH2 4.07Å; F78-Y91 HydrophobicContact CD1-CD2 4.08Å; F78-Y91 HydrophobicContact CD1-CE2 4.18Å; F78-Y91 HydrophobicContact CE1-CD2 4.4Å; F78-Y91 HydrophobicContact CE1-CG 4.49Å; F78-V99 HydrophobicContact CB-CG1 4.26Å; F78-V99 HydrophobicContact CB-CG2 4.25Å; F78-V99 HydrophobicContact CD1-CG2 4.37Å; F78-V99 HydrophobicContact CD2-CG2 3.5Å; F78-V99 HydrophobicContact CE2-CG2 3.91Å; F78-V99 HydrophobicContact CG-CG2 3.8Å; F78-V99 HydrophobicContact CZ-CG2 4.49Å
79	V	92.2	Very high	91.8	Very high	4 Å²	4	36.8 Å²	36.8	2%	0.024	24%	0.24	C	C	.	.	H	α-helix	trans	-64.7	-45.1	173.6	179.3	0	0	0	0	110.3	L29 C75 F76 A81 S82 I83 Q173 F330	L29-V79 HydrophobicContact CD2-CB 3.97Å; L29-V79 HydrophobicContact CD2-CG1 3.62Å; C75-V79 PolarHBondContact O-N 3.42Å; F76-V79 PolarHBondContact O-N 3.01Å; V79-A81 VanDerWaalsContact C-N 3.3Å; V79-A81 PolarHBondContact O-N 2.93Å; V79-S82 PolarHBondContact O-N 3.25Å; V79-S82 VanDerWaalsContact O-N 3.16Å; V79-I83 HydrophobicContact CG1-CD1 4.13Å; V79-I83 WeakPolarHBondContact O-CG1 3.5Å; V79-I83 PolarHBondContact O-N 3.24Å; V79-Q173 HydrophobicContact CG2-CB 3.97Å; V79-F330 HydrophobicContact CG1-CE2 4.12Å; V79-F330 HydrophobicContact CG1-CZ 4.18Å; V79-F330 HydrophobicContact CG2-CZ 4.19Å
80	M	92.4	Very high	91.4	Very high	45 Å²	45	38.9 Å²	38.9	22%	0.222	26%	0.255	C	S	.	.	H	α-helix	trans	-58.5	-42.3	174.5	-71	-177.3	69.9	0	0	112.1	L26 L29 M33 F76 P77 S82 I83 G84	L26-M80 HydrophobicContact CD2-CB 4.09Å; L26-M80 HydrophobicContact CD2-CE 4.42Å; L26-M80 HydrophobicContact CD2-CG 4.47Å; L26-M80 VanDerWaalsContact CD2-O 3.28Å; L26-M80 WeakPolarHBondContact CD2-O 3.29Å; L29-M80 HydrophobicContact CB-CG 4.35Å; L29-M80 HydrophobicContact CD2-CB 4.45Å; L29-M80 HydrophobicContact CD2-CG 3.46Å; L29-M80 VanDerWaalsContact CD2-CG 3.46Å; L29-M80 HydrophobicContact CG-CG 3.8Å; L29-M80 HydrophobicContact CG-SD 4.49Å; M33-M80 HydrophobicContact CE-SD 3.83Å; M33-M80 HydrophobicContact SD-SD 4.16Å; F76-M80 WeakPolarHBondContact O-CG 3.48Å; F76-M80 PolarHBondContact O-N 3.42Å; P77-M80 PolarHBondContact O-N 3.18Å; M80-S82 VanDerWaalsContact C-N 3.33Å; M80-S82 PolarHBondContact O-N 3.32Å; M80-I83 PolarHBondContact O-N 3.07Å; M80-G84 PolarHBondContact O-N 3.38Å
81	A	92.1	Very high	90.9	Very high	26 Å²	26	40.9 Å²	40.9	22%	0.215	26%	0.257	C	S	.	.	H	α-helix	trans	-65.2	-36.7	177.7	0	0	0	0	0	112.4	P77 F78 V79 G84 A85 Y91	P77-A81 WeakPolarHBondContact O-CB 3.46Å; P77-A81 PolarHBondContact O-N 3.01Å; F78-A81 PolarHBondContact O-N 3.28Å; V79-A81 VanDerWaalsContact C-N 3.3Å; V79-A81 PolarHBondContact O-N 2.93Å; A81-G84 PolarHBondContact O-N 3.32Å; A81-A85 WeakPolarHBondContact O-CB 3.03Å; A81-A85 PolarHBondContact O-N 2.87Å; A81-Y91 HydrophobicContact CB-CE2 3.66Å; A81-Y91 VanDerWaalsContact CB-OH 3.29Å; A81-Y91 WeakPolarHBondContact CB-OH 3.33Å
82	S	91.5	Very high	90.5	Very high	0 Å²	0	41.7 Å²	41.7	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-65.5	-41.9	174.9	-173.4	0	0	0	0	112.3	F78 V79 M80 G84 A85 G86 S87 D88 F167	F78-S82 PolarHBondContact O-N 3.43Å; V79-S82 PolarHBondContact O-N 3.25Å; V79-S82 VanDerWaalsContact O-N 3.16Å; M80-S82 VanDerWaalsContact C-N 3.33Å; M80-S82 PolarHBondContact O-N 3.32Å; S82-G84 VanDerWaalsContact C-N 3.33Å; S82-G84 PolarHBondContact O-N 3.38Å; S82-A85 PolarHBondContact O-N 2.74Å; S82-G86 PolarHBondContact O-N 3.43Å; S82-S87 WeakPolarHBondContact O-CA 3.45Å; S82-S87 PolarHBondContact O-N 2.9Å; S82-D88 WeakPolarHBondContact CA-O 3.16Å; S82-D88 PolarHBondContact OG-O 3.43Å; S82-F167 WeakPolarHBondContact OG-CE2 3.41Å; S82-F167 VanDerWaalsContact OG-CZ 3.28Å; S82-F167 WeakPolarHBondContact OG-CZ 3.31Å
83	I	90.2	Very high	90.1	Very high	4 Å²	4	45.4 Å²	45.4	2%	0.021	30%	0.304	C	S	.	.	H	α-helix	trans	-62.4	-42.9	174.5	-61.6	162.2	0	0	0	110.5	K25 L26 L29 V79 M80 A85 G86 E172	K25-I83 HydrophobicContact CB-CD1 4.31Å; K25-I83 HydrophobicContact CB-CG2 4.11Å; L26-I83 HydrophobicContact CD1-CG2 4.46Å; L26-I83 HydrophobicContact CD2-CB 3.9Å; L26-I83 HydrophobicContact CD2-CG2 3.92Å; L26-I83 HydrophobicContact CG-CB 4.34Å; L26-I83 HydrophobicContact CG-CG2 3.77Å; L29-I83 HydrophobicContact CD2-CD1 4.01Å; V79-I83 HydrophobicContact CG1-CD1 4.13Å; V79-I83 WeakPolarHBondContact O-CG1 3.5Å; V79-I83 PolarHBondContact O-N 3.24Å; M80-I83 PolarHBondContact O-N 3.07Å; I83-A85 PolarHBondContact O-N 3.09Å; I83-G86 PolarHBondContact O-N 2.93Å; I83-E172 HydrophobicContact CG1-CB 4.02Å; I83-E172 HydrophobicContact CG1-CG 4.46Å
84	G	88.1	Confident	89.7	Confident	57 Å²	57	49.2 Å²	49.2	59%	0.588	32%	0.317	S	S	*	.	H	α-helix	trans	-65.3	-26	177.5	0	0	0	0	0	114	M80 A81 S82 G86	M80-G84 PolarHBondContact O-N 3.38Å; A81-G84 PolarHBondContact O-N 3.32Å; S82-G84 VanDerWaalsContact C-N 3.33Å; S82-G84 PolarHBondContact O-N 3.38Å; G84-G86 VanDerWaalsContact C-N 3.3Å
85	A	87.4	Confident	89.5	Confident	46 Å²	46	48.3 Å²	48.3	38%	0.38	31%	0.312	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84.5	2.6	176.3	0	0	0	0	0	113.8	A81 S82 I83 P90	A81-A85 WeakPolarHBondContact O-CB 3.03Å; A81-A85 PolarHBondContact O-N 2.87Å; S82-A85 PolarHBondContact O-N 2.74Å; I83-A85 PolarHBondContact O-N 3.09Å; A85-P90 HydrophobicContact CB-CG 4.29Å
86	G	84.5	Confident	89.4	Confident	56 Å²	56	48.6 Å²	48.6	58%	0.577	31%	0.314	S	S	*	.	T	Hydrogen-bonded Turn	trans	86.4	36.8	-178.3	0	0	0	0	0	113.8	S82 I83 G84 D88	S82-G86 PolarHBondContact O-N 3.43Å; I83-G86 PolarHBondContact O-N 2.93Å; G84-G86 VanDerWaalsContact C-N 3.3Å; G86-D88 VanDerWaalsContact C-N 3.29Å; G86-D88 PolarHBondContact O-N 3.26Å
87	S	84.1	Confident	89.1	Confident	35 Å²	35	52.2 Å²	52.2	25%	0.245	33%	0.33	C	S	.	.	S	Bend	trans	63.9	35.3	-177.5	-46.8	0	0	0	0	112.5	S82 F167 E172	S82-S87 WeakPolarHBondContact O-CA 3.45Å; S82-S87 PolarHBondContact O-N 2.9Å; S87-F167 WeakPolarHBondContact O-CE1 3.41Å; S87-F167 WeakPolarHBondContact O-CZ 3.16Å; S87-E172 PolarHBondContact OG-OE1 3.09Å
88	D	86.6	Confident	89	Confident	105 Å²	105	53.8 Å²	53.8	56%	0.561	33%	0.334	S	S	*	.			trans	-118.7	161.8	174.6	-86.8	-27.6	0	0	0	111.1	S82 G86 P90	S82-D88 WeakPolarHBondContact CA-O 3.16Å; S82-D88 PolarHBondContact OG-O 3.43Å; G86-D88 VanDerWaalsContact C-N 3.29Å; G86-D88 PolarHBondContact O-N 3.26Å; D88-P90 WeakPolarHBondContact O-CD 3.13Å
89	W	88.2	Confident	88.9	Confident	37 Å²	37	51 Å²	51	14%	0.14	32%	0.323	C	S	.	.			trans	-110.2	99.5	178.8	-171.7	-93.5	0	0	0	112.5	F78 Y91 G92 S95 C96 V99 F167 C174	F78-W89 HydrophobicContact CB-CH2 3.79Å; F78-W89 HydrophobicContact CB-CZ3 4.13Å; F78-W89 AromaticContact CD1-CH2 3.94Å; F78-W89 HydrophobicContact CD1-CH2 3.94Å; F78-W89 HydrophobicContact CD1-CZ2 4.37Å; F78-W89 HydrophobicContact CG-CH2 4.07Å; W89-Y91 HydrophobicContact CZ2-CD2 4.26Å; W89-G92 VanDerWaalsContact CD1-O 3.23Å; W89-G92 PolarHBondContact NE1-O 3.07Å; W89-S95 PolarHBondContact NE1-OG 3.27Å; W89-C96 HydrophobicContact CD2-CB 4.29Å; W89-C96 HydrophobicContact CG-CB 4.39Å; W89-C96 HydrophobicContact CZ2-CB 4.18Å; W89-V99 HydrophobicContact CH2-CB 4.17Å; W89-V99 HydrophobicContact CH2-CG1 4.27Å; W89-V99 HydrophobicContact CH2-CG2 4.03Å; W89-V99 HydrophobicContact CZ2-CG2 4.38Å; W89-F167 HydrophobicContact CB-CB 4.27Å; W89-F167 HydrophobicContact CB-CD1 4.3Å; W89-F167 HydrophobicContact CB-CD2 3.96Å; W89-F167 HydrophobicContact CB-CE2 4.41Å; W89-F167 HydrophobicContact CB-CG 3.89Å; W89-F167 HydrophobicContact CE3-CD2 4.13Å; W89-F167 HydrophobicContact CE3-CE2 4.39Å; W89-C174 VanDerWaalsContact CD2-SG 3.6Å; W89-C174 VanDerWaalsContact CE3-SG 3.58Å
90	P	87.3	Confident	88.9	Confident	82 Å²	82	50.9 Å²	50.9	53%	0.532	32%	0.322	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84	-13.2	-174.4	32	-35.4	0	0	0	114.3	A85 D88 G92	A85-P90 HydrophobicContact CB-CG 4.29Å; D88-P90 WeakPolarHBondContact O-CD 3.13Å; P90-G92 VanDerWaalsContact C-N 3.32Å; P90-G92 PolarHBondContact O-N 2.99Å
91	Y	86.3	Confident	88.9	Confident	123 Å²	123	50.6 Å²	50.6	48%	0.482	32%	0.319	S	S	.	.	T	Hydrogen-bonded Turn	trans	-87.6	9.3	-169	-58.1	-74.1	0	0	0	114.8	F78 A81 W89 S95	F78-Y91 HydrophobicContact CD1-CD2 4.08Å; F78-Y91 HydrophobicContact CD1-CE2 4.18Å; F78-Y91 HydrophobicContact CE1-CD2 4.4Å; F78-Y91 HydrophobicContact CE1-CG 4.49Å; A81-Y91 HydrophobicContact CB-CE2 3.66Å; A81-Y91 VanDerWaalsContact CB-OH 3.29Å; A81-Y91 WeakPolarHBondContact CB-OH 3.33Å; W89-Y91 HydrophobicContact CZ2-CD2 4.26Å; Y91-S95 WeakPolarHBondContact CB-OG 3.21Å; Y91-S95 PolarHBondContact O-OG 3Å
92	G	88.1	Confident	89	Confident	40 Å²	40	51.2 Å²	51.2	41%	0.412	32%	0.319	S	S	.	.	H	α-helix	trans	79.5	171	-179.1	0	0	0	0	0	115	W89 P90 S95 C96	W89-G92 VanDerWaalsContact CD1-O 3.23Å; W89-G92 PolarHBondContact NE1-O 3.07Å; P90-G92 VanDerWaalsContact C-N 3.32Å; P90-G92 PolarHBondContact O-N 2.99Å; G92-S95 PolarHBondContact O-OG 3.23Å; G92-C96 PolarHBondContact O-N 3.48Å
93	A	86.4	Confident	89.1	Confident	78 Å²	78	52.5 Å²	52.5	65%	0.645	33%	0.328	S	S	*	.	H	α-helix	trans	-71	-34.2	-171.2	0	0	0	0	0	114.2	C96 K97	A93-C96 WeakPolarHBondContact O-CB 3.33Å; A93-C96 PolarHBondContact O-N 3.49Å; A93-K97 PolarHBondContact O-N 3.37Å; A93-K97 VanDerWaalsContact O-N 3.09Å
94	L	88.5	Confident	89.1	Confident	130 Å²	130	53.5 Å²	53.5	68%	0.681	33%	0.334	S	S	*	.	H	α-helix	trans	-65.9	-44.8	-178.3	178.6	61.9	0	0	0	111.8	C96 K97 I98	L94-C96 VanDerWaalsContact C-N 3.3Å; L94-C96 PolarHBondContact O-N 3.47Å; L94-K97 PolarHBondContact O-N 3.49Å; L94-I98 HydrophobicContact CD1-CD1 4.21Å; L94-I98 HydrophobicContact CD1-CG1 4.46Å; L94-I98 HydrophobicContact CG-CD1 4Å; L94-I98 WeakPolarHBondContact O-CG1 3.28Å; L94-I98 PolarHBondContact O-N 2.81Å
95	S	89.9	Confident	89.4	Confident	25 Å²	25	51.3 Å²	51.3	18%	0.175	31%	0.309	C	S	.	.	H	α-helix	trans	-62.8	-38.7	177.5	58.9	0	0	0	0	111.4	W89 Y91 G92 K97 I98 V99	W89-S95 PolarHBondContact NE1-OG 3.27Å; Y91-S95 WeakPolarHBondContact CB-OG 3.21Å; Y91-S95 PolarHBondContact O-OG 3Å; G92-S95 PolarHBondContact O-OG 3.23Å; S95-K97 PolarHBondContact O-N 3.37Å; S95-I98 PolarHBondContact O-N 2.91Å; S95-V99 WeakPolarHBondContact O-CB 3.36Å; S95-V99 WeakPolarHBondContact O-CG2 3.32Å; S95-V99 PolarHBondContact O-N 3.48Å
96	C	90.4	Very high	89.8	Confident	9 Å²	9	49.5 Å²	49.5	6%	0.061	29%	0.292	C	S	.	.	H	α-helix	trans	-60.1	-46.7	174.5	-173.6	0	0	0	0	111.7	W89 G92 A93 L94 I98 V99 A100 F167 C174	W89-C96 HydrophobicContact CD2-CB 4.29Å; W89-C96 HydrophobicContact CG-CB 4.39Å; W89-C96 HydrophobicContact CZ2-CB 4.18Å; G92-C96 PolarHBondContact O-N 3.48Å; A93-C96 WeakPolarHBondContact O-CB 3.33Å; A93-C96 PolarHBondContact O-N 3.49Å; L94-C96 VanDerWaalsContact C-N 3.3Å; L94-C96 PolarHBondContact O-N 3.47Å; C96-I98 VanDerWaalsContact C-N 3.34Å; C96-I98 PolarHBondContact O-N 3.39Å; C96-V99 PolarHBondContact O-N 2.88Å; C96-A100 VanDerWaalsContact O-CB 3.29Å; C96-A100 WeakPolarHBondContact O-CB 3.34Å; C96-A100 PolarHBondContact O-N 3.12Å; C96-F167 PolarHBondContact SG-N 3.04Å; C96-C174 WeakPolarHBondContact CA-SG 3.19Å; C96-C174 HydrophobicContact CB-CB 4.04Å; C96-C174 WeakPolarHBondContact CB-SG 3.32Å; C96-C174 VanDerWaalsContact O-CB 3.31Å; C96-C174 WeakPolarHBondContact O-CB 3.41Å; C96-C174 WeakPolarHBondContact SG-CB 3.31Å; C96-C174 CovalentContact SG-SG 2.03Å; C96-C174 PolarHBondContact SG-SG 3.31Å
97	K	89.6	Confident	90.2	Very high	78 Å²	78	47.5 Å²	47.5	34%	0.339	27%	0.269	S	S	.	.	H	α-helix	trans	-60.4	-42.1	175.9	-71.5	-171	175.1	-163.2	0	112	A93 L94 S95 F101 D161	A93-K97 PolarHBondContact O-N 3.37Å; A93-K97 VanDerWaalsContact O-N 3.09Å; L94-K97 PolarHBondContact O-N 3.49Å; S95-K97 PolarHBondContact O-N 3.37Å; K97-F101 VanDerWaalsContact O-CB 3.32Å; K97-F101 WeakPolarHBondContact O-CB 3.29Å; K97-F101 PolarHBondContact O-N 2.94Å; K97-D161 IonicContact NZ-OD1 3.72Å
98	I	91.3	Very high	90.7	Very high	87 Å²	87	46.3 Å²	46.3	45%	0.446	26%	0.26	S	S	.	.	H	α-helix	trans	-65.6	-46.9	178.7	-67.3	167.2	0	0	0	111.2	L94 S95 C96 F101 L102	L94-I98 HydrophobicContact CD1-CD1 4.21Å; L94-I98 HydrophobicContact CD1-CG1 4.46Å; L94-I98 HydrophobicContact CG-CD1 4Å; L94-I98 WeakPolarHBondContact O-CG1 3.28Å; L94-I98 PolarHBondContact O-N 2.81Å; S95-I98 PolarHBondContact O-N 2.91Å; C96-I98 VanDerWaalsContact C-N 3.34Å; C96-I98 PolarHBondContact O-N 3.39Å; I98-F101 PolarHBondContact O-N 3.18Å; I98-L102 HydrophobicContact CG2-CD1 4.08Å; I98-L102 HydrophobicContact CG2-CG 4.45Å; I98-L102 WeakPolarHBondContact O-CG 3.44Å; I98-L102 PolarHBondContact O-N 2.88Å
99	V	92.8	Very high	91.1	Very high	5 Å²	5	41.3 Å²	41.3	3%	0.03	23%	0.233	C	C	.	.	H	α-helix	trans	-65.9	-39.3	-179.6	171.6	0	0	0	0	111.3	F78 W89 S95 C96 L102 S103	F78-V99 HydrophobicContact CB-CG1 4.26Å; F78-V99 HydrophobicContact CB-CG2 4.25Å; F78-V99 HydrophobicContact CD1-CG2 4.37Å; F78-V99 HydrophobicContact CD2-CG2 3.5Å; F78-V99 HydrophobicContact CE2-CG2 3.91Å; F78-V99 HydrophobicContact CG-CG2 3.8Å; F78-V99 HydrophobicContact CZ-CG2 4.49Å; W89-V99 HydrophobicContact CH2-CB 4.17Å; W89-V99 HydrophobicContact CH2-CG1 4.27Å; W89-V99 HydrophobicContact CH2-CG2 4.03Å; W89-V99 HydrophobicContact CZ2-CG2 4.38Å; S95-V99 WeakPolarHBondContact O-CB 3.36Å; S95-V99 WeakPolarHBondContact O-CG2 3.32Å; S95-V99 PolarHBondContact O-N 3.48Å; C96-V99 PolarHBondContact O-N 2.88Å; V99-L102 PolarHBondContact O-N 3.37Å; V99-S103 WeakPolarHBondContact O-CB 3.08Å; V99-S103 PolarHBondContact O-N 3.36Å; V99-S103 PolarHBondContact O-OG 3.18Å
100	A	91.3	Very high	91.5	Very high	0 Å²	0	40.2 Å²	40.2	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-63	-47	173.5	0	0	0	0	0	111.5	C96 L102 S103 V104 Y165 C174	C96-A100 VanDerWaalsContact O-CB 3.29Å; C96-A100 WeakPolarHBondContact O-CB 3.34Å; C96-A100 PolarHBondContact O-N 3.12Å; A100-L102 PolarHBondContact O-N 2.92Å; A100-S103 PolarHBondContact O-N 3.3Å; A100-V104 WeakPolarHBondContact O-CG2 3.29Å; A100-V104 PolarHBondContact O-N 3.49Å; A100-Y165 HydrophobicContact CB-CD1 3.44Å; A100-Y165 VanDerWaalsContact CB-CD1 3.44Å; A100-Y165 HydrophobicContact CB-CD2 4.37Å; A100-Y165 HydrophobicContact CB-CE1 4.06Å; A100-Y165 HydrophobicContact CB-CG 3.64Å; A100-C174 VanDerWaalsContact CA-O 3.31Å; A100-C174 WeakPolarHBondContact CA-O 3.39Å; A100-C174 HydrophobicContact CB-CB 4.08Å; A100-C174 WeakPolarHBondContact CB-O 3.23Å
101	F	92.8	Very high	91.8	Very high	39 Å²	39	36.4 Å²	36.4	17%	0.171	21%	0.206	C	C	.	.	H	α-helix	trans	-57.2	-48.2	175.7	169.4	-95.9	0	0	0	112	K97 I98 S103 V104 L105 A155 F156 V159 Y165	K97-F101 VanDerWaalsContact O-CB 3.32Å; K97-F101 WeakPolarHBondContact O-CB 3.29Å; K97-F101 PolarHBondContact O-N 2.94Å; I98-F101 PolarHBondContact O-N 3.18Å; F101-S103 PolarHBondContact O-N 3.05Å; F101-V104 PolarHBondContact O-N 3.02Å; F101-L105 HydrophobicContact CE1-CD2 4Å; F101-L105 HydrophobicContact CZ-CD2 4.31Å; F101-L105 WeakPolarHBondContact O-CB 3.33Å; F101-L105 PolarHBondContact O-N 2.99Å; F101-A155 HydrophobicContact CD2-CB 3.93Å; F101-A155 WeakPolarHBondContact CD2-O 3.21Å; F101-A155 HydrophobicContact CE2-CB 3.66Å; F101-A155 HydrophobicContact CZ-CB 4.43Å; F101-F156 HydrophobicContact CE2-CD2 4.14Å; F101-V159 HydrophobicContact CD2-CG2 3.81Å; F101-V159 HydrophobicContact CE2-CG2 4.49Å; F101-V159 HydrophobicContact CG-CG2 4.47Å; F101-Y165 HydrophobicContact CB-CE2 4.02Å
102	L	94.4	Very high	92.3	Very high	39 Å²	39	31.7 Å²	31.7	20%	0.204	19%	0.188	C	C	.	.	H	α-helix	trans	-62	-43.9	178.7	-73.1	175.9	0	0	0	111.6	V74 I98 V99 A100 V104 L105 F106	V74-L102 HydrophobicContact CG1-CD1 3.81Å; I98-L102 HydrophobicContact CG2-CD1 4.08Å; I98-L102 HydrophobicContact CG2-CG 4.45Å; I98-L102 WeakPolarHBondContact O-CG 3.44Å; I98-L102 PolarHBondContact O-N 2.88Å; V99-L102 PolarHBondContact O-N 3.37Å; A100-L102 PolarHBondContact O-N 2.92Å; L102-V104 VanDerWaalsContact C-N 3.35Å; L102-V104 PolarHBondContact O-N 2.65Å; L102-L105 HydrophobicContact CD2-CD2 4.34Å; L102-L105 WeakPolarHBondContact O-CB 3.4Å; L102-L105 PolarHBondContact O-N 3.45Å; L102-F106 HydrophobicContact CB-CD2 4.45Å; L102-F106 HydrophobicContact CB-CE2 4.07Å; L102-F106 HydrophobicContact CD2-CE2 4.33Å; L102-F106 WeakPolarHBondContact O-CD2 3.37Å; L102-F106 WeakPolarHBondContact O-CG 3.44Å; L102-F106 PolarHBondContact O-N 3.01Å
103	S	92.4	Very high	92.7	Very high	27 Å²	27	29.8 Å²	29.8	19%	0.189	17%	0.168	C	C	.	.	H	α-helix	trans	-60.6	-44.4	178.8	-59.8	0	0	0	0	111.7	V99 A100 F101 C107	V99-S103 WeakPolarHBondContact O-CB 3.08Å; V99-S103 PolarHBondContact O-N 3.36Å; V99-S103 PolarHBondContact O-OG 3.18Å; A100-S103 PolarHBondContact O-N 3.3Å; F101-S103 PolarHBondContact O-N 3.05Å; S103-C107 WeakPolarHBondContact O-CB 3.42Å; S103-C107 PolarHBondContact O-N 3.05Å; S103-C107 VanDerWaalsContact O-N 3.15Å
104	V	91.1	Very high	93.2	Very high	25 Å²	25	26.3 Å²	26.3	15%	0.152	14%	0.139	C	C	.	.	H	α-helix	trans	-68.9	-40.8	176.6	173.6	0	0	0	0	111.7	A100 F101 L102 F106 C107 F108 A155 Y165	A100-V104 WeakPolarHBondContact O-CG2 3.29Å; A100-V104 PolarHBondContact O-N 3.49Å; F101-V104 PolarHBondContact O-N 3.02Å; L102-V104 VanDerWaalsContact C-N 3.35Å; L102-V104 PolarHBondContact O-N 2.65Å; V104-F106 PolarHBondContact O-N 3.48Å; V104-C107 WeakPolarHBondContact O-CB 3.46Å; V104-C107 PolarHBondContact O-N 3.34Å; V104-F108 HydrophobicContact CG1-CD2 3.61Å; V104-F108 HydrophobicContact CG1-CE2 3.54Å; V104-F108 WeakPolarHBondContact O-CD2 3.28Å; V104-F108 PolarHBondContact O-N 2.87Å; V104-A155 HydrophobicContact CG1-CB 4.05Å; V104-Y165 HydrophobicContact CG2-CE1 3.94Å
105	L	94.6	Very high	93.6	Very high	12 Å²	12	23.3 Å²	23.3	6%	0.063	12%	0.121	C	C	.	.	H	α-helix	trans	-56.5	-51	175.7	173.2	65.5	0	0	0	111.4	F101 L102 C107 F108 H109 W148 V152 A155	F101-L105 HydrophobicContact CE1-CD2 4Å; F101-L105 HydrophobicContact CZ-CD2 4.31Å; F101-L105 WeakPolarHBondContact O-CB 3.33Å; F101-L105 PolarHBondContact O-N 2.99Å; L102-L105 HydrophobicContact CD2-CD2 4.34Å; L102-L105 WeakPolarHBondContact O-CB 3.4Å; L102-L105 PolarHBondContact O-N 3.45Å; L105-C107 VanDerWaalsContact C-N 3.31Å; L105-C107 PolarHBondContact O-N 3.47Å; L105-F108 PolarHBondContact O-N 3.06Å; L105-H109 VanDerWaalsContact O-CB 3.27Å; L105-H109 WeakPolarHBondContact O-CB 3.42Å; L105-H109 PolarHBondContact O-N 3.25Å; L105-W148 HydrophobicContact CD2-CZ3 4.21Å; L105-W148 HydrophobicContact CG-CZ3 4.45Å; L105-V152 HydrophobicContact CD1-CB 4.31Å; L105-V152 HydrophobicContact CD1-CG2 3.6Å; L105-A155 HydrophobicContact CB-CB 4.03Å; L105-A155 HydrophobicContact CD1-CB 4.46Å
106	F	95.5	Very high	93.9	Very high	7 Å²	7	23 Å²	23	3%	0.031	12%	0.118	C	C	.	.	H	α-helix	trans	-65.6	-35.2	179.5	-68.1	-59	0	0	0	112.4	A67 L70 R71 L102 V104 H109 V110 W148	A67-F106 HydrophobicContact CB-CD1 4.28Å; L70-F106 HydrophobicContact CB-CE1 4.16Å; L70-F106 HydrophobicContact CB-CZ 4Å; L70-F106 HydrophobicContact CD2-CE1 3.81Å; L70-F106 HydrophobicContact CD2-CZ 3.51Å; L70-F106 HydrophobicContact CG-CE1 4.08Å; L70-F106 HydrophobicContact CG-CE2 4.44Å; L70-F106 HydrophobicContact CG-CZ 3.54Å; R71-F106 HydrophobicContact CB-CB 4.23Å; R71-F106 HydrophobicContact CB-CD1 4.41Å; R71-F106 HydrophobicContact CB-CD2 3.63Å; R71-F106 HydrophobicContact CB-CE2 4.12Å; R71-F106 HydrophobicContact CB-CG 3.85Å; R71-F106 HydrophobicContact CG-CB 4.22Å; R71-F106 HydrophobicContact CG-CD2 3.84Å; R71-F106 HydrophobicContact CG-CG 4.21Å; L102-F106 HydrophobicContact CB-CD2 4.45Å; L102-F106 HydrophobicContact CB-CE2 4.07Å; L102-F106 HydrophobicContact CD2-CE2 4.33Å; L102-F106 WeakPolarHBondContact O-CD2 3.37Å; L102-F106 WeakPolarHBondContact O-CG 3.44Å; L102-F106 PolarHBondContact O-N 3.01Å; V104-F106 PolarHBondContact O-N 3.48Å; F106-H109 PolarHBondContact O-N 3.26Å; F106-V110 WeakPolarHBondContact O-CG1 3.22Å; F106-V110 PolarHBondContact O-N 3.47Å; F106-W148 HydrophobicContact CD1-CH2 4.39Å; F106-W148 AromaticContact CE1-CH2 3.89Å; F106-W148 HydrophobicContact CE1-CH2 3.89Å; F106-W148 HydrophobicContact CE1-CZ3 4.4Å
107	C	92.9	Very high	94.1	Very high	14 Å²	14	22.6 Å²	22.6	10%	0.095	12%	0.115	C	C	.	.	H	α-helix	trans	-62.3	-47.2	175	-178.4	0	0	0	0	112	S103 V104 L105 V110 A111 W299	S103-C107 WeakPolarHBondContact O-CB 3.42Å; S103-C107 PolarHBondContact O-N 3.05Å; S103-C107 VanDerWaalsContact O-N 3.15Å; V104-C107 WeakPolarHBondContact O-CB 3.46Å; V104-C107 PolarHBondContact O-N 3.34Å; L105-C107 VanDerWaalsContact C-N 3.31Å; L105-C107 PolarHBondContact O-N 3.47Å; C107-V110 WeakPolarHBondContact O-CG1 3.39Å; C107-A111 PolarHBondContact O-N 3.33Å; C107-W299 HydrophobicContact CB-CH2 3.99Å; C107-W299 WeakPolarHBondContact SG-CH2 3.35Å; C107-W299 VanDerWaalsContact SG-CZ3 3.58Å
108	F	93.6	Very high	94.4	Very high	11 Å²	11	18.9 Å²	18.9	5%	0.048	10%	0.099	C	C	.	.	H	α-helix	trans	-68.8	-37.6	175.9	-79.5	-64	0	0	0	112.2	V104 L105 A111 F112 M154 F189 M192 L193	V104-F108 HydrophobicContact CG1-CD2 3.61Å; V104-F108 HydrophobicContact CG1-CE2 3.54Å; V104-F108 WeakPolarHBondContact O-CD2 3.28Å; V104-F108 PolarHBondContact O-N 2.87Å; L105-F108 PolarHBondContact O-N 3.06Å; F108-A111 PolarHBondContact O-N 2.58Å; F108-F112 HydrophobicContact CB-CD2 4.25Å; F108-F112 HydrophobicContact CB-CE2 4.2Å; F108-F112 HydrophobicContact CD1-CE2 4.29Å; F108-F112 WeakPolarHBondContact O-CD2 3.26Å; F108-F112 PolarHBondContact O-N 3.09Å; F108-M154 HydrophobicContact CD1-CB 4.44Å; F108-M154 HydrophobicContact CD2-CB 4.11Å; F108-M154 HydrophobicContact CE2-CB 4.34Å; F108-M154 HydrophobicContact CG-CB 4.17Å; F108-F189 HydrophobicContact CZ-CD1 4.45Å; F108-M192 HydrophobicContact CD1-CE 3.91Å; F108-M192 HydrophobicContact CE1-CE 3.25Å; F108-M192 HydrophobicContact CE2-CE 4.47Å; F108-M192 HydrophobicContact CZ-CE 3.59Å; F108-L193 HydrophobicContact CD1-CD1 4.26Å; F108-L193 HydrophobicContact CE1-CB 4.11Å; F108-L193 HydrophobicContact CE1-CD1 4.1Å
109	H	96.2	Very high	94.5	Very high	0 Å²	0	17.3 Å²	17.3	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-57.8	-50.8	176.3	175.1	82.6	0	0	0	111.9	D63 L105 F106 A111 F112 L113 W148 S151	D63-H109 IonicContact OD1-CE1 3.91Å; D63-H109 IonicContact OD2-CE1 3.13Å; D63-H109 PolarHBondContact OD2-CE1 2.84Å; D63-H109 IonicContact OD2-NE2 3.25Å; D63-H109 PolarHBondContact OD2-NE2 2.96Å; L105-H109 VanDerWaalsContact O-CB 3.27Å; L105-H109 WeakPolarHBondContact O-CB 3.42Å; L105-H109 PolarHBondContact O-N 3.25Å; F106-H109 PolarHBondContact O-N 3.26Å; H109-A111 VanDerWaalsContact C-N 3.33Å; H109-A111 PolarHBondContact O-N 3.47Å; H109-F112 PolarHBondContact O-N 3.33Å; H109-L113 WeakPolarHBondContact O-CB 3.18Å; H109-L113 PolarHBondContact O-N 2.91Å; H109-W148 AromaticContact CE1-CD1 3.76Å; H109-W148 AromaticContact CE1-CD2 3.94Å; H109-W148 AromaticContact CE1-CE2 3.41Å; H109-W148 VanDerWaalsContact CE1-CE2 3.41Å; H109-W148 AromaticContact CE1-CZ2 3.82Å; H109-W148 AromaticContact CE1-NE1 3.26Å; H109-W148 PolarHBondContact CE1-NE1 3.5Å; H109-W148 VanDerWaalsContact CE1-NE1 3.26Å; H109-W148 AromaticContact ND1-CD2 3.68Å; H109-W148 AromaticContact ND1-CE2 3.6Å; H109-W148 AromaticContact ND1-CG 3.98Å; H109-W148 AromaticContact ND1-NE1 3.79Å; H109-S151 WeakPolarHBondContact CA-OG 3.3Å; H109-S151 PolarHBondContact N-OG 3.21Å
110	V	95.8	Very high	94.6	Very high	13 Å²	13	17.4 Å²	17.4	8%	0.079	9%	0.094	C	C	.	.	H	α-helix	trans	-62.5	-40.5	176.8	64	0	0	0	0	111.6	L64 F106 C107 L113 L114 F295	L64-V110 HydrophobicContact CD1-CB 4.24Å; L64-V110 HydrophobicContact CD1-CG2 3.54Å; F106-V110 WeakPolarHBondContact O-CG1 3.22Å; F106-V110 PolarHBondContact O-N 3.47Å; C107-V110 WeakPolarHBondContact O-CG1 3.39Å; V110-L113 PolarHBondContact O-N 3.01Å; V110-L114 HydrophobicContact CG2-CD1 3.89Å; V110-L114 HydrophobicContact CG2-CG 4.11Å; V110-L114 WeakPolarHBondContact O-CB 3.47Å; V110-L114 WeakPolarHBondContact O-CG 3.35Å; V110-L114 PolarHBondContact O-N 2.76Å; V110-F295 HydrophobicContact CG1-CD2 4.16Å; V110-F295 HydrophobicContact CG1-CE2 3.48Å; V110-F295 VanDerWaalsContact CG1-CE2 3.48Å; V110-F295 HydrophobicContact CG1-CZ 4.21Å; V110-F295 HydrophobicContact CG2-CD2 4.17Å; V110-F295 HydrophobicContact CG2-CE2 4.29Å
111	A	94.8	Very high	94.7	Very high	3 Å²	3	17.5 Å²	17.5	3%	0.025	9%	0.094	C	C	.	.	H	α-helix	trans	-62.5	-48.6	179	0	0	0	0	0	112.4	C107 F108 H109 L114 F115 L193 I196 F295	C107-A111 PolarHBondContact O-N 3.33Å; F108-A111 PolarHBondContact O-N 2.58Å; H109-A111 VanDerWaalsContact C-N 3.33Å; H109-A111 PolarHBondContact O-N 3.47Å; A111-L114 PolarHBondContact O-N 3.3Å; A111-F115 PolarHBondContact O-N 3.01Å; A111-F115 VanDerWaalsContact O-N 3.08Å; A111-L193 HydrophobicContact CB-CD1 3.9Å; A111-I196 HydrophobicContact CB-CG2 4.08Å; A111-F295 HydrophobicContact CB-CZ 4.46Å
112	F	96.4	Very high	94.6	Very high	23 Å²	23	18.7 Å²	18.7	10%	0.101	10%	0.098	C	C	.	.	H	α-helix	trans	-67.1	-39.3	177.3	-75.7	-55.9	0	0	0	112.4	F108 H109 F115 C116 V147 L150 M154 I196	F108-F112 HydrophobicContact CB-CD2 4.25Å; F108-F112 HydrophobicContact CB-CE2 4.2Å; F108-F112 HydrophobicContact CD1-CE2 4.29Å; F108-F112 WeakPolarHBondContact O-CD2 3.26Å; F108-F112 PolarHBondContact O-N 3.09Å; H109-F112 PolarHBondContact O-N 3.33Å; F112-F115 WeakPolarHBondContact O-CB 3.38Å; F112-F115 PolarHBondContact O-N 3.13Å; F112-C116 PolarHBondContact O-N 2.79Å; F112-C116 PolarHBondContact O-SG 3.27Å; F112-C116 VanDerWaalsContact O-SG 3.41Å; F112-V147 HydrophobicContact CB-CG1 3.89Å; F112-V147 HydrophobicContact CB-CG2 4.42Å; F112-L150 HydrophobicContact CD2-CB 4.22Å; F112-L150 HydrophobicContact CE2-CB 4.12Å; F112-L150 HydrophobicContact CZ-CB 4.44Å; F112-M154 HydrophobicContact CE2-CG 3.97Å; F112-M154 HydrophobicContact CZ-CG 4.08Å; F112-I196 HydrophobicContact CD1-CD1 3.96Å; F112-I196 HydrophobicContact CD1-CG1 4.41Å; F112-I196 HydrophobicContact CD1-CG2 4.35Å; F112-I196 HydrophobicContact CE1-CD1 3.27Å; F112-I196 HydrophobicContact CE1-CG1 3.89Å; F112-I196 HydrophobicContact CE2-CD1 4.23Å; F112-I196 HydrophobicContact CZ-CD1 3.43Å; F112-I196 VanDerWaalsContact CZ-CD1 3.43Å; F112-I196 HydrophobicContact CZ-CG1 4.49Å
113	L	96.9	Very high	94.5	Very high	1 Å²	1	19.8 Å²	19.8	1%	0.005	10%	0.103	C	C	.	.	H	α-helix	trans	-62.6	-46	176.7	-173.9	61	0	0	0	111	F60 D63 L64 H109 V110 F115 C116 V117 V147	F60-L113 HydrophobicContact CB-CD1 4.36Å; F60-L113 HydrophobicContact CD1-CD1 3.97Å; D63-L113 HydrophobicContact CB-CD2 4.37Å; D63-L113 WeakPolarHBondContact OD2-CD2 3.4Å; L64-L113 HydrophobicContact CB-CD2 3.76Å; L64-L113 HydrophobicContact CD1-CD2 4.15Å; H109-L113 WeakPolarHBondContact O-CB 3.18Å; H109-L113 PolarHBondContact O-N 2.91Å; V110-L113 PolarHBondContact O-N 3.01Å; L113-F115 VanDerWaalsContact C-N 3.29Å; L113-F115 PolarHBondContact O-N 2.83Å; L113-C116 PolarHBondContact O-N 3.45Å; L113-V117 HydrophobicContact CD1-CG2 4.45Å; L113-V117 HydrophobicContact CG-CG2 4.41Å; L113-V117 WeakPolarHBondContact O-CB 3.38Å; L113-V117 VanDerWaalsContact O-CG2 3.23Å; L113-V117 WeakPolarHBondContact O-CG2 3.38Å; L113-V117 PolarHBondContact O-N 3.43Å; L113-V147 HydrophobicContact CB-CG1 4.08Å
114	L	95.6	Very high	94.4	Very high	4 Å²	4	18.5 Å²	18.5	2%	0.021	9%	0.094	C	C	.	.	H	α-helix	trans	-61.8	-37.3	176.6	-69.2	176.9	0	0	0	111.9	V110 A111 V117 S118 T200 I291 F295	V110-L114 HydrophobicContact CG2-CD1 3.89Å; V110-L114 HydrophobicContact CG2-CG 4.11Å; V110-L114 WeakPolarHBondContact O-CB 3.47Å; V110-L114 WeakPolarHBondContact O-CG 3.35Å; V110-L114 PolarHBondContact O-N 2.76Å; A111-L114 PolarHBondContact O-N 3.3Å; L114-V117 PolarHBondContact O-N 2.79Å; L114-S118 WeakPolarHBondContact O-CB 3.22Å; L114-S118 PolarHBondContact O-N 2.97Å; L114-T200 HydrophobicContact CB-CG2 4.47Å; L114-I291 HydrophobicContact CD2-CG2 3.89Å; L114-F295 HydrophobicContact CD1-CB 3.81Å; L114-F295 HydrophobicContact CD1-CD1 4.29Å; L114-F295 HydrophobicContact CD1-CD2 4.16Å; L114-F295 HydrophobicContact CD1-CG 3.81Å
115	F	96.4	Very high	94.3	Very high	68 Å²	68	17.9 Å²	17.9	30%	0.298	9%	0.09	S	C	.	.	H	α-helix	trans	-60.2	-53.6	171.3	177	-105.6	0	0	0	111.5	A111 F112 L113 V117 S118 V119 I196 T200 V203	A111-F115 PolarHBondContact O-N 3.01Å; A111-F115 VanDerWaalsContact O-N 3.08Å; F112-F115 WeakPolarHBondContact O-CB 3.38Å; F112-F115 PolarHBondContact O-N 3.13Å; L113-F115 VanDerWaalsContact C-N 3.29Å; L113-F115 PolarHBondContact O-N 2.83Å; F115-V117 VanDerWaalsContact C-N 3.29Å; F115-V117 PolarHBondContact O-N 3.27Å; F115-S118 WeakPolarHBondContact O-CB 3.33Å; F115-S118 PolarHBondContact O-N 3.32Å; F115-S118 VanDerWaalsContact O-N 3.07Å; F115-S118 PolarHBondContact O-OG 3.5Å; F115-V119 HydrophobicContact CE1-CG2 4.23Å; F115-V119 HydrophobicContact CE2-CG2 4.26Å; F115-V119 HydrophobicContact CZ-CG2 4.01Å; F115-V119 PolarHBondContact O-N 3.27Å; F115-V119 VanDerWaalsContact O-N 3.11Å; F115-I196 HydrophobicContact CB-CG2 4.36Å; F115-T200 WeakPolarHBondContact CA-OG1 3.3Å; F115-T200 WeakPolarHBondContact CB-OG1 3.49Å; F115-V203 HydrophobicContact CE2-CG2 4.32Å
116	C	96.3	Very high	94	Very high	17 Å²	17	18.2 Å²	18.2	12%	0.115	10%	0.095	C	C	.	.	H	α-helix	trans	-60.8	-37.4	179.1	-69.9	0	0	0	0	112.6	F112 L113 V119 T120 V143 M146 V147	F112-C116 PolarHBondContact O-N 2.79Å; F112-C116 PolarHBondContact O-SG 3.27Å; F112-C116 VanDerWaalsContact O-SG 3.41Å; L113-C116 PolarHBondContact O-N 3.45Å; C116-V119 PolarHBondContact O-N 2.72Å; C116-T120 WeakPolarHBondContact O-CB 3.5Å; C116-T120 PolarHBondContact O-N 3.27Å; C116-T120 PolarHBondContact O-OG1 3.42Å; C116-V143 HydrophobicContact CB-CG1 3.88Å; C116-M146 VanDerWaalsContact SG-CE 3.58Å; C116-V147 HydrophobicContact CB-CG2 4.36Å
117	V	95.6	Very high	93.6	Very high	2 Å²	2	22.5 Å²	22.5	1%	0.012	11%	0.114	C	C	.	.	H	α-helix	trans	-63.6	-44.1	173.7	170	0	0	0	0	110.6	F60 L113 L114 F115 V119 T120 R121 Y288	F60-V117 HydrophobicContact CB-CG2 3.61Å; F60-V117 HydrophobicContact CD2-CG2 4.2Å; F60-V117 HydrophobicContact CG-CG2 3.92Å; L113-V117 HydrophobicContact CD1-CG2 4.45Å; L113-V117 HydrophobicContact CG-CG2 4.41Å; L113-V117 WeakPolarHBondContact O-CB 3.38Å; L113-V117 VanDerWaalsContact O-CG2 3.23Å; L113-V117 WeakPolarHBondContact O-CG2 3.38Å; L113-V117 PolarHBondContact O-N 3.43Å; L114-V117 PolarHBondContact O-N 2.79Å; F115-V117 VanDerWaalsContact C-N 3.29Å; F115-V117 PolarHBondContact O-N 3.27Å; V117-V119 VanDerWaalsContact C-N 3.33Å; V117-V119 PolarHBondContact O-N 3.36Å; V117-T120 WeakPolarHBondContact O-CB 3.46Å; V117-T120 PolarHBondContact O-N 3Å; V117-T120 VanDerWaalsContact O-N 3.16Å; V117-R121 HydrophobicContact CG1-CG 4.09Å; V117-R121 VanDerWaalsContact O-CG 3.3Å; V117-R121 WeakPolarHBondContact O-CG 3.34Å; V117-R121 PolarHBondContact O-N 3.42Å; V117-Y288 HydrophobicContact CG1-CD1 3.44Å; V117-Y288 VanDerWaalsContact CG1-CD1 3.44Å; V117-Y288 HydrophobicContact CG1-CD2 4.09Å; V117-Y288 HydrophobicContact CG1-CE1 3.73Å; V117-Y288 HydrophobicContact CG1-CE2 4.33Å; V117-Y288 HydrophobicContact CG1-CG 3.6Å; V117-Y288 HydrophobicContact CG2-CE1 4.43Å
118	S	95.4	Very high	93.2	Very high	0 Å²	0	24.1 Å²	24.1	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-57.8	-45.4	177.9	80.2	0	0	0	0	112.1	L114 F115 R121 Y122 V203	L114-S118 WeakPolarHBondContact O-CB 3.22Å; L114-S118 PolarHBondContact O-N 2.97Å; F115-S118 WeakPolarHBondContact O-CB 3.33Å; F115-S118 PolarHBondContact O-N 3.32Å; F115-S118 VanDerWaalsContact O-N 3.07Å; F115-S118 PolarHBondContact O-OG 3.5Å; S118-R121 PolarHBondContact O-N 3.43Å; S118-Y122 WeakPolarHBondContact O-CB 3.31Å; S118-Y122 PolarHBondContact O-N 2.84Å; S118-V203 WeakPolarHBondContact OG-CG1 3.33Å
119	V	94.6	Very high	92.8	Very high	54 Å²	54	34.1 Å²	34.1	33%	0.327	16%	0.158	S	C	.	.	H	α-helix	trans	-63.7	-44.8	176.3	176.6	0	0	0	0	110.2	F115 C116 V117 R121 Y122 M123 V203	F115-V119 HydrophobicContact CE1-CG2 4.23Å; F115-V119 HydrophobicContact CE2-CG2 4.26Å; F115-V119 HydrophobicContact CZ-CG2 4.01Å; F115-V119 PolarHBondContact O-N 3.27Å; F115-V119 VanDerWaalsContact O-N 3.11Å; C116-V119 PolarHBondContact O-N 2.72Å; V117-V119 VanDerWaalsContact C-N 3.33Å; V117-V119 PolarHBondContact O-N 3.36Å; V119-R121 PolarHBondContact O-N 3.44Å; V119-Y122 WeakPolarHBondContact O-CB 3.43Å; V119-Y122 PolarHBondContact O-N 2.87Å; V119-M123 HydrophobicContact CG1-CG 4.4Å; V119-M123 VanDerWaalsContact O-CG 3.28Å; V119-M123 WeakPolarHBondContact O-CG 3.33Å; V119-M123 PolarHBondContact O-N 2.64Å; V119-V203 HydrophobicContact CG2-CG1 4.41Å
120	T	93.4	Very high	92.4	Very high	7 Å²	7	39.3 Å²	39.3	4%	0.043	18%	0.181	C	C	.	.	H	α-helix	trans	-61.3	-44.5	178.6	-61.4	0	0	0	0	111.7	F60 C116 V117 M123 A124 Y131 M135	F60-T120 HydrophobicContact CE2-CG2 3.95Å; C116-T120 WeakPolarHBondContact O-CB 3.5Å; C116-T120 PolarHBondContact O-N 3.27Å; C116-T120 PolarHBondContact O-OG1 3.42Å; V117-T120 WeakPolarHBondContact O-CB 3.46Å; V117-T120 PolarHBondContact O-N 3Å; V117-T120 VanDerWaalsContact O-N 3.16Å; T120-M123 PolarHBondContact O-N 3.07Å; T120-A124 WeakPolarHBondContact O-CB 3.27Å; T120-A124 PolarHBondContact O-N 3.33Å; T120-Y131 HydrophobicContact CG2-CD2 4.45Å; T120-Y131 HydrophobicContact CG2-CE2 3.72Å; T120-M135 HydrophobicContact CG2-CE 3.75Å
121	R	93.4	Very high	92	Very high	1 Å²	1	39.8 Å²	39.8	0%	0.004	18%	0.181	C	C	.	.	H	α-helix	trans	-65.4	-41.2	177.9	-67.3	-54.6	85.9	-158	-1.7	111.3	V117 S118 V119 A124 I125 Y131 M207 E281 Y288	V117-R121 HydrophobicContact CG1-CG 4.09Å; V117-R121 VanDerWaalsContact O-CG 3.3Å; V117-R121 WeakPolarHBondContact O-CG 3.34Å; V117-R121 PolarHBondContact O-N 3.42Å; S118-R121 PolarHBondContact O-N 3.43Å; V119-R121 PolarHBondContact O-N 3.44Å; R121-A124 PolarHBondContact O-N 2.97Å; R121-I125 WeakPolarHBondContact O-CG1 3.5Å; R121-I125 PolarHBondContact O-N 3.11Å; R121-Y131 PolarHBondContact NH2-OH 2.91Å; R121-M207 HydrophobicContact CB-SD 3.89Å; R121-E281 IonicContact CZ-OE2 3.7Å; R121-E281 IonicContact NH1-OE2 2.65Å; R121-E281 PolarHBondContact NH1-OE2 2.7Å; R121-Y288 HydrophobicContact CG-CD2 4.32Å
122	Y	92.1	Very high	91.5	Very high	65 Å²	65	43.4 Å²	43.4	26%	0.255	21%	0.206	S	C	.	.	H	α-helix	trans	-58.3	-48.6	172.5	175.9	-100.8	0	0	0	111.3	S118 V119 A124 I125 A126 M207	S118-Y122 WeakPolarHBondContact O-CB 3.31Å; S118-Y122 PolarHBondContact O-N 2.84Å; V119-Y122 WeakPolarHBondContact O-CB 3.43Å; V119-Y122 PolarHBondContact O-N 2.87Å; Y122-A124 PolarHBondContact O-N 3.31Å; Y122-I125 PolarHBondContact O-N 2.97Å; Y122-A126 HydrophobicContact CD2-CB 4.39Å; Y122-A126 HydrophobicContact CE1-CB 4.24Å; Y122-A126 HydrophobicContact CE2-CB 4Å; Y122-A126 VanDerWaalsContact O-CB 3.3Å; Y122-A126 WeakPolarHBondContact O-CB 3.39Å; Y122-A126 PolarHBondContact O-N 3.45Å; Y122-M207 HydrophobicContact CD2-CB 4.02Å
123	M	91.6	Very high	91	Very high	61 Å²	61	51.1 Å²	51.1	30%	0.3	24%	0.24	S	C	.	.	H	α-helix	trans	-63.3	-38.4	178.4	-69.2	-61	-124.7	0	0	113	V119 T120 I125 H127 F130	V119-M123 HydrophobicContact CG1-CG 4.4Å; V119-M123 VanDerWaalsContact O-CG 3.28Å; V119-M123 WeakPolarHBondContact O-CG 3.33Å; V119-M123 PolarHBondContact O-N 2.64Å; T120-M123 PolarHBondContact O-N 3.07Å; M123-I125 VanDerWaalsContact C-N 3.31Å; M123-I125 PolarHBondContact O-N 3.3Å; M123-H127 CarbonylContact O-C 3.54Å; M123-H127 VanDerWaalsContact O-CA 3.29Å; M123-H127 WeakPolarHBondContact O-CA 3.44Å; M123-H127 PolarHBondContact O-N 3.4Å; M123-H127 HydrophobicContact SD-CB 4.46Å; M123-F130 HydrophobicContact CE-CD1 4.31Å; M123-F130 HydrophobicContact CE-CE1 4.12Å
124	A	90.5	Very high	90.5	Very high	0 Å²	0	59 Å²	59	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-61.3	-39.4	176.7	0	0	0	0	0	112.4	T120 R121 Y122 H128 Y131	T120-A124 WeakPolarHBondContact O-CB 3.27Å; T120-A124 PolarHBondContact O-N 3.33Å; R121-A124 PolarHBondContact O-N 2.97Å; Y122-A124 PolarHBondContact O-N 3.31Å; A124-H128 WeakPolarHBondContact O-CA 3.25Å; A124-Y131 HydrophobicContact CB-CD1 3.97Å; A124-Y131 HydrophobicContact CB-CD2 3.77Å; A124-Y131 HydrophobicContact CB-CE1 3.99Å; A124-Y131 HydrophobicContact CB-CE2 3.78Å; A124-Y131 HydrophobicContact CB-CG 3.86Å
125	I	88.8	Confident	90.2	Very high	12 Å²	12	61 Å²	61	6%	0.062	28%	0.279	C	S	.	.	H	α-helix	trans	-85.8	-47.4	-177	-63.6	175.1	0	0	0	111.8	R121 Y122 M123 M207 F210 V211 F278	R121-I125 WeakPolarHBondContact O-CG1 3.5Å; R121-I125 PolarHBondContact O-N 3.11Å; Y122-I125 PolarHBondContact O-N 2.97Å; M123-I125 VanDerWaalsContact C-N 3.31Å; M123-I125 PolarHBondContact O-N 3.3Å; I125-M207 HydrophobicContact CD1-CG 4.06Å; I125-M207 HydrophobicContact CD1-SD 3.84Å; I125-F210 HydrophobicContact CG2-CD1 4.09Å; I125-F210 HydrophobicContact CG2-CE1 4.11Å; I125-V211 HydrophobicContact CD1-CG2 4.32Å; I125-V211 HydrophobicContact CG2-CG2 3.65Å; I125-F278 HydrophobicContact CG2-CE2 4.08Å; I125-F278 HydrophobicContact CG2-CZ 4.47Å
126	A	88.2	Confident	89.9	Confident	20 Å²	20	61.9 Å²	61.9	17%	0.165	29%	0.287	C	S	.	.	H	α-helix	trans	-80.9	-35.7	-175	0	0	0	0	0	113.2	Y122 F210	Y122-A126 HydrophobicContact CD2-CB 4.39Å; Y122-A126 HydrophobicContact CE1-CB 4.24Å; Y122-A126 HydrophobicContact CE2-CB 4Å; Y122-A126 VanDerWaalsContact O-CB 3.3Å; Y122-A126 WeakPolarHBondContact O-CB 3.39Å; Y122-A126 PolarHBondContact O-N 3.45Å; A126-F210 VanDerWaalsContact CA-CE1 3.45Å; A126-F210 HydrophobicContact CB-CD1 4.14Å; A126-F210 HydrophobicContact CB-CD2 4.44Å; A126-F210 HydrophobicContact CB-CE1 3.79Å; A126-F210 HydrophobicContact CB-CE2 4.09Å; A126-F210 HydrophobicContact CB-CG 4.45Å; A126-F210 HydrophobicContact CB-CZ 3.74Å
127	H	87.6	Confident	89.6	Confident	97 Å²	97	65.6 Å²	65.6	45%	0.449	31%	0.305	S	S	.	.			trans	-128.6	50.5	-175	-61.9	-64	0	0	0	111.8	M123 R129 F130 Y131	M123-H127 CarbonylContact O-C 3.54Å; M123-H127 VanDerWaalsContact O-CA 3.29Å; M123-H127 WeakPolarHBondContact O-CA 3.44Å; M123-H127 PolarHBondContact O-N 3.4Å; M123-H127 HydrophobicContact SD-CB 4.46Å; H127-R129 VanDerWaalsContact C-N 3.26Å; H127-R129 PolarHBondContact O-N 3.47Å; H127-R129 VanDerWaalsContact O-N 3.07Å; H127-F130 HydrophobicContact CB-CB 4.19Å; H127-F130 WeakPolarHBondContact O-CB 3.49Å; H127-F130 PolarHBondContact O-N 2.87Å; H127-Y131 PolarHBondContact O-N 3.46Å
128	H	84.9	Confident	89.5	Confident	48 Å²	48	70 Å²	70	22%	0.222	34%	0.335	C	S	.	.	H	α-helix	trans	-47	-42.8	-176.5	-175.3	-91.4	0	0	0	114.4	A124 F130 Y131 S132	A124-H128 WeakPolarHBondContact O-CA 3.25Å; H128-F130 VanDerWaalsContact C-N 3.34Å; H128-F130 PolarHBondContact O-N 2.88Å; H128-Y131 PolarHBondContact O-N 2.87Å; H128-S132 WeakPolarHBondContact O-CB 3.27Å; H128-S132 PolarHBondContact O-N 3.43Å
129	R	84.4	Confident	89.4	Confident	220 Å²	220	72.4 Å²	72.4	83%	0.83	35%	0.35	S	S	*	.	H	α-helix	trans	-62.8	-38.3	179	-74.3	-175.1	-81.8	176.9	-5	112.9	H127	H127-R129 VanDerWaalsContact C-N 3.26Å; H127-R129 PolarHBondContact O-N 3.47Å; H127-R129 VanDerWaalsContact O-N 3.07Å
130	F	87	Confident	89.4	Confident	110 Å²	110	69.9 Å²	69.9	48%	0.482	33%	0.334	S	S	.	.	H	α-helix	trans	-73	-46.3	176.9	-179.9	-94.4	0	0	0	110.3	M123 H127 H128 S132 K133 R134	M123-F130 HydrophobicContact CE-CD1 4.31Å; M123-F130 HydrophobicContact CE-CE1 4.12Å; H127-F130 HydrophobicContact CB-CB 4.19Å; H127-F130 WeakPolarHBondContact O-CB 3.49Å; H127-F130 PolarHBondContact O-N 2.87Å; H128-F130 VanDerWaalsContact C-N 3.34Å; H128-F130 PolarHBondContact O-N 2.88Å; F130-S132 PolarHBondContact O-N 3.18Å; F130-K133 PolarHBondContact O-N 3.46Å; F130-R134 HydrophobicContact CD1-CB 4.5Å; F130-R134 HydrophobicContact CD1-CG 4.37Å; F130-R134 HydrophobicContact CD2-CG 4.2Å; F130-R134 HydrophobicContact CE1-CB 4.22Å; F130-R134 HydrophobicContact CE1-CG 4Å; F130-R134 HydrophobicContact CE2-CG 3.83Å; F130-R134 HydrophobicContact CG-CG 4.47Å; F130-R134 HydrophobicContact CZ-CB 4.42Å; F130-R134 HydrophobicContact CZ-CG 3.73Å; F130-R134 WeakPolarHBondContact O-CB 3.13Å; F130-R134 PolarHBondContact O-N 3.13Å
131	Y	88.3	Confident	89.4	Confident	23 Å²	23	73 Å²	73	9%	0.09	35%	0.353	C	S	.	.	H	α-helix	trans	-55.9	-51.9	177.6	174	-94.1	0	0	0	112.1	P57 T120 R121 A124 H127 H128 K133 R134 M135	P57-Y131 WeakPolarHBondContact CD-OH 3.08Å; T120-Y131 HydrophobicContact CG2-CD2 4.45Å; T120-Y131 HydrophobicContact CG2-CE2 3.72Å; R121-Y131 PolarHBondContact NH2-OH 2.91Å; A124-Y131 HydrophobicContact CB-CD1 3.97Å; A124-Y131 HydrophobicContact CB-CD2 3.77Å; A124-Y131 HydrophobicContact CB-CE1 3.99Å; A124-Y131 HydrophobicContact CB-CE2 3.78Å; A124-Y131 HydrophobicContact CB-CG 3.86Å; H127-Y131 PolarHBondContact O-N 3.46Å; H128-Y131 PolarHBondContact O-N 2.87Å; Y131-K133 PolarHBondContact O-N 2.99Å; Y131-R134 PolarHBondContact O-N 3.5Å; Y131-M135 HydrophobicContact CD2-CB 4.02Å; Y131-M135 HydrophobicContact CD2-CG 3.53Å; Y131-M135 HydrophobicContact CE2-CB 3.86Å; Y131-M135 HydrophobicContact CE2-CG 3.5Å; Y131-M135 HydrophobicContact CG-CB 4.5Å; Y131-M135 HydrophobicContact CG-CG 4.37Å; Y131-M135 WeakPolarHBondContact O-CB 3.26Å; Y131-M135 PolarHBondContact O-N 3.49Å
132	S	83.9	Confident	89.6	Confident	78 Å²	78	75.7 Å²	75.7	55%	0.545	38%	0.376	S	S	.	.	H	α-helix	trans	-60.4	-30.4	-179.1	174.3	0	0	0	0	113.4	H128 F130	H128-S132 WeakPolarHBondContact O-CB 3.27Å; H128-S132 PolarHBondContact O-N 3.43Å; F130-S132 PolarHBondContact O-N 3.18Å
133	K	86.4	Confident	89.8	Confident	186 Å²	186	73.9 Å²	73.9	81%	0.809	37%	0.371	S	S	*	.	H	α-helix	trans	-84.9	-32.5	177.5	-72.6	-171	176.6	-169.7	0	114	F130 Y131	F130-K133 PolarHBondContact O-N 3.46Å; Y131-K133 PolarHBondContact O-N 2.99Å
134	R	87.1	Confident	90	Very high	165 Å²	165	72.2 Å²	72.2	62%	0.623	36%	0.364	S	S	*	.	H	α-helix	trans	-99	-32.2	-171.4	-76.5	-73.9	-168.3	168.8	0.4	113.6	F130 Y131 N136 T139	F130-R134 HydrophobicContact CD1-CB 4.5Å; F130-R134 HydrophobicContact CD1-CG 4.37Å; F130-R134 HydrophobicContact CD2-CG 4.2Å; F130-R134 HydrophobicContact CE1-CB 4.22Å; F130-R134 HydrophobicContact CE1-CG 4Å; F130-R134 HydrophobicContact CE2-CG 3.83Å; F130-R134 HydrophobicContact CG-CG 4.47Å; F130-R134 HydrophobicContact CZ-CB 4.42Å; F130-R134 HydrophobicContact CZ-CG 3.73Å; F130-R134 WeakPolarHBondContact O-CB 3.13Å; F130-R134 PolarHBondContact O-N 3.13Å; Y131-R134 PolarHBondContact O-N 3.5Å; R134-N136 PolarHBondContact O-N 2.91Å; R134-T139 PolarHBondContact O-OG1 2.92Å; R134-T139 VanDerWaalsContact O-OG1 3.1Å
135	M	87.4	Confident	90.4	Very high	48 Å²	48	75.5 Å²	75.5	24%	0.236	39%	0.386	C	S	.	.			trans	-82.7	90.7	-178.5	-80.1	-61.4	-168.3	0	0	111.1	A56 T120 Y131 T139	A56-M135 HydrophobicContact CB-CB 4.3Å; T120-M135 HydrophobicContact CG2-CE 3.75Å; Y131-M135 HydrophobicContact CD2-CB 4.02Å; Y131-M135 HydrophobicContact CD2-CG 3.53Å; Y131-M135 HydrophobicContact CE2-CB 3.86Å; Y131-M135 HydrophobicContact CE2-CG 3.5Å; Y131-M135 HydrophobicContact CG-CB 4.5Å; Y131-M135 HydrophobicContact CG-CG 4.37Å; Y131-M135 WeakPolarHBondContact O-CB 3.26Å; Y131-M135 PolarHBondContact O-N 3.49Å; M135-T139 HydrophobicContact SD-CG2 3.81Å
136	N	90.3	Very high	90.8	Very high	85 Å²	85	78.8 Å²	78.8	46%	0.455	40%	0.402	S	S	.	.			trans	-111.6	174.3	168.6	62.3	16.1	0	0	0	110.5	R134 C138 T139 C140	R134-N136 PolarHBondContact O-N 2.91Å; N136-C138 VanDerWaalsContact C-N 3.32Å; N136-C138 PolarHBondContact O-N 2.81Å; N136-C138 PolarHBondContact OD1-N 3.39Å; N136-T139 PolarHBondContact O-N 3.28Å; N136-T139 VanDerWaalsContact OD1-CB 3.31Å; N136-T139 WeakPolarHBondContact OD1-CB 3.36Å; N136-T139 PolarHBondContact OD1-N 2.79Å; N136-T139 PolarHBondContact OD1-OG1 2.85Å; N136-C140 PolarHBondContact O-N 3.22Å; N136-C140 PolarHBondContact O-SG 2.96Å
137	L	90.2	Very high	91.2	Very high	96 Å²	96	77.8 Å²	77.8	50%	0.503	39%	0.394	S	S	.	.	H	α-helix	trans	-55.9	-45.1	180	177.6	61.9	0	0	0	112.2	Y59 T139 C140 V141	Y59-L137 HydrophobicContact CD2-CD1 4.05Å; Y59-L137 HydrophobicContact CE1-CD1 4.2Å; Y59-L137 HydrophobicContact CE2-CD1 3.64Å; L137-T139 VanDerWaalsContact C-N 3.32Å; L137-T139 PolarHBondContact O-N 3.16Å; L137-C140 WeakPolarHBondContact O-CB 3.23Å; L137-C140 PolarHBondContact O-N 3.2Å; L137-C140 VanDerWaalsContact O-N 3.11Å; L137-V141 HydrophobicContact CD1-CG2 4.11Å; L137-V141 HydrophobicContact CG-CG2 4.38Å; L137-V141 WeakPolarHBondContact O-CG2 3.44Å; L137-V141 PolarHBondContact O-N 3.24Å
138	C	93.6	Very high	91.7	Very high	94 Å²	94	76.7 Å²	76.7	64%	0.635	39%	0.386	S	S	*	.	H	α-helix	trans	-59.3	-42.8	179.9	-176.3	0	0	0	0	111.9	N136 V141 A142	N136-C138 VanDerWaalsContact C-N 3.32Å; N136-C138 PolarHBondContact O-N 2.81Å; N136-C138 PolarHBondContact OD1-N 3.39Å; C138-V141 PolarHBondContact O-N 2.94Å; C138-A142 WeakPolarHBondContact O-CB 3.39Å; C138-A142 PolarHBondContact O-N 3.35Å
139	T	93.3	Very high	92.3	Very high	50 Å²	50	78.7 Å²	78.7	31%	0.307	40%	0.401	S	S	.	.	H	α-helix	trans	-65.1	-40.6	176.2	-55.7	0	0	0	0	111.3	R134 M135 N136 L137 A142 V143	R134-T139 PolarHBondContact O-OG1 2.92Å; R134-T139 VanDerWaalsContact O-OG1 3.1Å; M135-T139 HydrophobicContact SD-CG2 3.81Å; N136-T139 PolarHBondContact O-N 3.28Å; N136-T139 VanDerWaalsContact OD1-CB 3.31Å; N136-T139 WeakPolarHBondContact OD1-CB 3.36Å; N136-T139 PolarHBondContact OD1-N 2.79Å; N136-T139 PolarHBondContact OD1-OG1 2.85Å; L137-T139 VanDerWaalsContact C-N 3.32Å; L137-T139 PolarHBondContact O-N 3.16Å; T139-A142 PolarHBondContact O-N 3.27Å; T139-V143 WeakPolarHBondContact O-CG2 3.49Å; T139-V143 PolarHBondContact O-N 3.31Å
140	C	94.3	Very high	92.8	Very high	1 Å²	1	71.4 Å²	71.4	1%	0.007	38%	0.379	C	S	.	.	H	α-helix	trans	-62.9	-45.7	176.6	-60.8	0	0	0	0	111.3	A56 Y59 F60 N136 L137 V143 I144	A56-C140 VanDerWaalsContact CB-SG 3.54Å; Y59-C140 HydrophobicContact CD2-CB 4.18Å; F60-C140 HydrophobicContact CE1-CB 4.44Å; F60-C140 HydrophobicContact CZ-CB 4.25Å; N136-C140 PolarHBondContact O-N 3.22Å; N136-C140 PolarHBondContact O-SG 2.96Å; L137-C140 WeakPolarHBondContact O-CB 3.23Å; L137-C140 PolarHBondContact O-N 3.2Å; L137-C140 VanDerWaalsContact O-N 3.11Å; C140-V143 PolarHBondContact O-N 3.06Å; C140-I144 WeakPolarHBondContact O-CG1 3.31Å; C140-I144 PolarHBondContact O-N 3.5Å
141	V	94.9	Very high	93.2	Very high	73 Å²	73	66.2 Å²	66.2	44%	0.442	36%	0.356	S	S	.	.	H	α-helix	trans	-61.6	-44.2	176	172.8	0	0	0	0	110.8	L137 C138 V143 I144 C145	L137-V141 HydrophobicContact CD1-CG2 4.11Å; L137-V141 HydrophobicContact CG-CG2 4.38Å; L137-V141 WeakPolarHBondContact O-CG2 3.44Å; L137-V141 PolarHBondContact O-N 3.24Å; C138-V141 PolarHBondContact O-N 2.94Å; V141-V143 VanDerWaalsContact C-N 3.34Å; V141-V143 PolarHBondContact O-N 3.1Å; V141-I144 PolarHBondContact O-N 3.27Å; V141-C145 WeakPolarHBondContact O-CB 3.36Å; V141-C145 PolarHBondContact O-N 3.12Å; V141-C145 PolarHBondContact O-SG 2.94Å
142	A	96.4	Very high	93.5	Very high	58 Å²	58	68 Å²	68	48%	0.479	37%	0.369	S	S	.	.	H	α-helix	trans	-60.3	-41.7	176.7	0	0	0	0	0	112.4	C138 T139 C145 M146	C138-A142 WeakPolarHBondContact O-CB 3.39Å; C138-A142 PolarHBondContact O-N 3.35Å; T139-A142 PolarHBondContact O-N 3.27Å; A142-C145 PolarHBondContact O-N 3.26Å; A142-M146 WeakPolarHBondContact O-CB 3.5Å; A142-M146 PolarHBondContact O-N 3.45Å
143	V	96.3	Very high	93.9	Very high	26 Å²	26	67 Å²	67	16%	0.158	37%	0.365	C	S	.	.	H	α-helix	trans	-63.2	-45.2	174.5	170.4	0	0	0	0	110.9	F60 C116 T139 C140 V141 M146 V147	F60-V143 HydrophobicContact CE1-CB 4.06Å; F60-V143 HydrophobicContact CE1-CG1 3.74Å; F60-V143 HydrophobicContact CZ-CB 4.34Å; F60-V143 HydrophobicContact CZ-CG1 4.13Å; C116-V143 HydrophobicContact CB-CG1 3.88Å; T139-V143 WeakPolarHBondContact O-CG2 3.49Å; T139-V143 PolarHBondContact O-N 3.31Å; C140-V143 PolarHBondContact O-N 3.06Å; V141-V143 VanDerWaalsContact C-N 3.34Å; V141-V143 PolarHBondContact O-N 3.1Å; V143-M146 HydrophobicContact CG1-CE 4.22Å; V143-M146 PolarHBondContact O-N 2.49Å; V143-V147 HydrophobicContact CG1-CG2 4.5Å; V143-V147 WeakPolarHBondContact O-CG2 3.28Å; V143-V147 PolarHBondContact O-N 3.32Å
144	I	97.1	Very high	94.1	Very high	27 Å²	27	60.8 Å²	60.8	14%	0.138	34%	0.34	C	S	.	.	H	α-helix	trans	-60.9	-48.4	177.4	-70.1	164.6	0	0	0	110.5	F60 D63 C140 V141 M146 V147 W148	F60-I144 HydrophobicContact CD1-CD1 4.32Å; F60-I144 HydrophobicContact CD1-CG1 4.02Å; F60-I144 HydrophobicContact CE1-CG1 4.1Å; D63-I144 HydrophobicContact CB-CD1 4.08Å; D63-I144 HydrophobicContact CB-CG1 4.3Å; D63-I144 HydrophobicContact CB-CG2 4.5Å; D63-I144 WeakPolarHBondContact OD1-CG2 3.37Å; C140-I144 WeakPolarHBondContact O-CG1 3.31Å; C140-I144 PolarHBondContact O-N 3.5Å; V141-I144 PolarHBondContact O-N 3.27Å; I144-M146 VanDerWaalsContact C-N 3.32Å; I144-M146 PolarHBondContact O-N 3.24Å; I144-V147 WeakPolarHBondContact O-CB 3.23Å; I144-V147 PolarHBondContact O-N 3.12Å; I144-V147 VanDerWaalsContact O-N 3.1Å; I144-W148 VanDerWaalsContact O-CD1 3.26Å; I144-W148 PolarHBondContact O-N 2.88Å
145	C	97.4	Very high	94.1	Very high	69 Å²	69	52.9 Å²	52.9	47%	0.466	31%	0.31	S	S	.	.	H	α-helix	trans	-57.9	-44.1	176.6	-69.5	0	0	0	0	111.9	V141 A142 V147 W148 T149	V141-C145 WeakPolarHBondContact O-CB 3.36Å; V141-C145 PolarHBondContact O-N 3.12Å; V141-C145 PolarHBondContact O-SG 2.94Å; A142-C145 PolarHBondContact O-N 3.26Å; C145-V147 VanDerWaalsContact C-N 3.34Å; C145-V147 PolarHBondContact O-N 3.26Å; C145-W148 PolarHBondContact O-N 2.85Å; C145-T149 WeakPolarHBondContact O-CG2 3.36Å; C145-T149 PolarHBondContact O-N 3.35Å; C145-T149 PolarHBondContact O-OG1 3.24Å
146	M	97.4	Very high	94.1	Very high	80 Å²	80	54.9 Å²	54.9	39%	0.394	32%	0.318	S	S	.	.	H	α-helix	trans	-61.3	-41	175.1	175.9	-152.9	63.3	0	0	111.9	C116 A142 V143 I144 T149 L150	C116-M146 VanDerWaalsContact SG-CE 3.58Å; A142-M146 WeakPolarHBondContact O-CB 3.5Å; A142-M146 PolarHBondContact O-N 3.45Å; V143-M146 HydrophobicContact CG1-CE 4.22Å; V143-M146 PolarHBondContact O-N 2.49Å; I144-M146 VanDerWaalsContact C-N 3.32Å; I144-M146 PolarHBondContact O-N 3.24Å; M146-T149 WeakPolarHBondContact CA-OG1 3.47Å; M146-T149 PolarHBondContact O-N 3.11Å; M146-T149 PolarHBondContact O-OG1 3.06Å; M146-L150 HydrophobicContact CG-CD1 3.99Å; M146-L150 HydrophobicContact CG-CG 4.46Å; M146-L150 WeakPolarHBondContact O-CB 3.32Å; M146-L150 VanDerWaalsContact O-CG 3.27Å; M146-L150 WeakPolarHBondContact O-CG 3.24Å; M146-L150 PolarHBondContact O-N 3.04Å; M146-L150 HydrophobicContact SD-CD1 4.44Å
147	V	97.9	Very high	93.9	Very high	0 Å²	0	52.8 Å²	52.8	0%	0	31%	0.309	C	S	.	.	H	α-helix	trans	-63.1	-45.8	176.6	169	0	0	0	0	110.6	F112 L113 C116 V143 I144 C145 T149 L150 S151	F112-V147 HydrophobicContact CB-CG1 3.89Å; F112-V147 HydrophobicContact CB-CG2 4.42Å; L113-V147 HydrophobicContact CB-CG1 4.08Å; C116-V147 HydrophobicContact CB-CG2 4.36Å; V143-V147 HydrophobicContact CG1-CG2 4.5Å; V143-V147 WeakPolarHBondContact O-CG2 3.28Å; V143-V147 PolarHBondContact O-N 3.32Å; I144-V147 WeakPolarHBondContact O-CB 3.23Å; I144-V147 PolarHBondContact O-N 3.12Å; I144-V147 VanDerWaalsContact O-N 3.1Å; C145-V147 VanDerWaalsContact C-N 3.34Å; C145-V147 PolarHBondContact O-N 3.26Å; V147-T149 PolarHBondContact O-N 2.73Å; V147-L150 PolarHBondContact O-N 3.36Å; V147-S151 WeakPolarHBondContact O-CB 3.28Å; V147-S151 PolarHBondContact O-N 3.16Å; V147-S151 PolarHBondContact O-OG 3.41Å
148	W	97.8	Very high	93.3	Very high	73 Å²	73	48.4 Å²	48.4	28%	0.277	29%	0.286	S	S	.	.	H	α-helix	trans	-60	-45.5	176.1	-82.9	101.9	0	0	0	112.5	D63 L105 F106 H109 I144 C145 S151 V152	D63-W148 PolarHBondContact OD1-NE1 3.43Å; D63-W148 VanDerWaalsContact OD1-NE1 3.14Å; L105-W148 HydrophobicContact CD2-CZ3 4.21Å; L105-W148 HydrophobicContact CG-CZ3 4.45Å; F106-W148 HydrophobicContact CD1-CH2 4.39Å; F106-W148 AromaticContact CE1-CH2 3.89Å; F106-W148 HydrophobicContact CE1-CH2 3.89Å; F106-W148 HydrophobicContact CE1-CZ3 4.4Å; H109-W148 AromaticContact CE1-CD1 3.76Å; H109-W148 AromaticContact CE1-CD2 3.94Å; H109-W148 AromaticContact CE1-CE2 3.41Å; H109-W148 VanDerWaalsContact CE1-CE2 3.41Å; H109-W148 AromaticContact CE1-CZ2 3.82Å; H109-W148 AromaticContact CE1-NE1 3.26Å; H109-W148 PolarHBondContact CE1-NE1 3.5Å; H109-W148 VanDerWaalsContact CE1-NE1 3.26Å; H109-W148 AromaticContact ND1-CD2 3.68Å; H109-W148 AromaticContact ND1-CE2 3.6Å; H109-W148 AromaticContact ND1-CG 3.98Å; H109-W148 AromaticContact ND1-NE1 3.79Å; I144-W148 VanDerWaalsContact O-CD1 3.26Å; I144-W148 PolarHBondContact O-N 2.88Å; C145-W148 PolarHBondContact O-N 2.85Å; W148-S151 PolarHBondContact O-N 3.47Å; W148-V152 WeakPolarHBondContact O-CG2 3.36Å; W148-V152 PolarHBondContact O-N 3.09Å
149	T	97	Very high	92.6	Very high	90 Å²	90	46.4 Å²	46.4	55%	0.552	27%	0.271	S	S	*	.	H	α-helix	trans	-65.6	-43.1	179.7	55.7	0	0	0	0	112.3	C145 M146 V147 S151 V152 A153	C145-T149 WeakPolarHBondContact O-CG2 3.36Å; C145-T149 PolarHBondContact O-N 3.35Å; C145-T149 PolarHBondContact O-OG1 3.24Å; M146-T149 WeakPolarHBondContact CA-OG1 3.47Å; M146-T149 PolarHBondContact O-N 3.11Å; M146-T149 PolarHBondContact O-OG1 3.06Å; V147-T149 PolarHBondContact O-N 2.73Å; T149-S151 VanDerWaalsContact C-N 3.3Å; T149-S151 PolarHBondContact O-N 2.96Å; T149-V152 PolarHBondContact O-N 3.28Å; T149-A153 WeakPolarHBondContact O-CB 3.34Å; T149-A153 PolarHBondContact O-N 2.74Å
150	L	95.3	Very high	91.7	Very high	68 Å²	68	50.4 Å²	50.4	36%	0.356	28%	0.284	S	S	.	.	H	α-helix	trans	-61.8	-39.6	174.7	-72.8	172.5	0	0	0	111.7	F112 M146 V147 A153 M154	F112-L150 HydrophobicContact CD2-CB 4.22Å; F112-L150 HydrophobicContact CE2-CB 4.12Å; F112-L150 HydrophobicContact CZ-CB 4.44Å; M146-L150 HydrophobicContact CG-CD1 3.99Å; M146-L150 HydrophobicContact CG-CG 4.46Å; M146-L150 WeakPolarHBondContact O-CB 3.32Å; M146-L150 VanDerWaalsContact O-CG 3.27Å; M146-L150 WeakPolarHBondContact O-CG 3.24Å; M146-L150 PolarHBondContact O-N 3.04Å; M146-L150 HydrophobicContact SD-CD1 4.44Å; V147-L150 PolarHBondContact O-N 3.36Å; L150-A153 PolarHBondContact O-N 2.91Å; L150-M154 VanDerWaalsContact O-CG 3.29Å; L150-M154 WeakPolarHBondContact O-CG 3.25Å; L150-M154 PolarHBondContact O-N 3.09Å
151	S	95.9	Very high	90.4	Very high	0 Å²	0	55.4 Å²	55.4	0%	0	31%	0.311	C	S	.	.	H	α-helix	trans	-66.9	-42.6	179.7	-53.1	0	0	0	0	111.8	H109 V147 W148 T149 M154 A155	H109-S151 WeakPolarHBondContact CA-OG 3.3Å; H109-S151 PolarHBondContact N-OG 3.21Å; V147-S151 WeakPolarHBondContact O-CB 3.28Å; V147-S151 PolarHBondContact O-N 3.16Å; V147-S151 PolarHBondContact O-OG 3.41Å; W148-S151 PolarHBondContact O-N 3.47Å; T149-S151 VanDerWaalsContact C-N 3.3Å; T149-S151 PolarHBondContact O-N 2.96Å; S151-M154 PolarHBondContact O-N 2.9Å; S151-A155 WeakPolarHBondContact O-CB 3.22Å; S151-A155 PolarHBondContact O-N 3.22Å
152	V	94.5	Very high	88.7	Confident	60 Å²	60	55.2 Å²	55.2	36%	0.364	31%	0.31	S	S	.	.	H	α-helix	trans	-62.4	-47.7	173.4	171.9	0	0	0	0	110.3	L105 W148 T149 M154 A155 F156	L105-V152 HydrophobicContact CD1-CB 4.31Å; L105-V152 HydrophobicContact CD1-CG2 3.6Å; W148-V152 WeakPolarHBondContact O-CG2 3.36Å; W148-V152 PolarHBondContact O-N 3.09Å; T149-V152 PolarHBondContact O-N 3.28Å; V152-M154 PolarHBondContact O-N 3.39Å; V152-M154 VanDerWaalsContact O-N 3.16Å; V152-A155 PolarHBondContact O-N 3.37Å; V152-A155 VanDerWaalsContact O-N 3.12Å; V152-F156 VanDerWaalsContact O-CB 3.28Å; V152-F156 WeakPolarHBondContact O-CB 3.27Å; V152-F156 PolarHBondContact O-N 3Å
153	A	92.4	Very high	87	Confident	57 Å²	57	53 Å²	53	47%	0.471	29%	0.293	S	S	.	.	H	α-helix	trans	-56.6	-33.5	179.1	0	0	0	0	0	112.6	T149 L150 P157	T149-A153 WeakPolarHBondContact O-CB 3.34Å; T149-A153 PolarHBondContact O-N 2.74Å; L150-A153 PolarHBondContact O-N 2.91Å; A153-P157 WeakPolarHBondContact O-CD 3.28Å
154	M	88.6	Confident	85.9	Confident	56 Å²	56	53.3 Å²	53.3	28%	0.276	29%	0.294	S	S	.	.	H	α-helix	trans	-83.5	-31.4	177.3	-65.8	-52.2	178.5	0	0	114.1	F108 F112 L150 S151 V152 P157 F189 M192	F108-M154 HydrophobicContact CD1-CB 4.44Å; F108-M154 HydrophobicContact CD2-CB 4.11Å; F108-M154 HydrophobicContact CE2-CB 4.34Å; F108-M154 HydrophobicContact CG-CB 4.17Å; F112-M154 HydrophobicContact CE2-CG 3.97Å; F112-M154 HydrophobicContact CZ-CG 4.08Å; L150-M154 VanDerWaalsContact O-CG 3.29Å; L150-M154 WeakPolarHBondContact O-CG 3.25Å; L150-M154 PolarHBondContact O-N 3.09Å; S151-M154 PolarHBondContact O-N 2.9Å; V152-M154 PolarHBondContact O-N 3.39Å; V152-M154 VanDerWaalsContact O-N 3.16Å; M154-P157 WeakPolarHBondContact O-CD 3.5Å; M154-F189 WeakPolarHBondContact O-CE1 3.39Å; M154-M192 HydrophobicContact CB-CE 3.73Å; M154-M192 HydrophobicContact CE-CE 4.12Å; M154-M192 HydrophobicContact CE-SD 3.33Å; M154-M192 WeakPolarHBondContact CE-SD 3.42Å; M154-M192 HydrophobicContact CG-CE 3.38Å; M154-M192 HydrophobicContact CG-SD 3.94Å; M154-M192 HydrophobicContact SD-CE 3.38Å; M154-M192 WeakPolarHBondContact SD-CE 3.47Å; M154-M192 HydrophobicContact SD-SD 3.32Å
155	A	89.1	Confident	85.3	Confident	0 Å²	0	52.4 Å²	52.4	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-81.8	-18	179	0	0	0	0	0	113.6	F101 V104 L105 S151 V152 Y165	F101-A155 HydrophobicContact CD2-CB 3.93Å; F101-A155 WeakPolarHBondContact CD2-O 3.21Å; F101-A155 HydrophobicContact CE2-CB 3.66Å; F101-A155 HydrophobicContact CZ-CB 4.43Å; V104-A155 HydrophobicContact CG1-CB 4.05Å; L105-A155 HydrophobicContact CB-CB 4.03Å; L105-A155 HydrophobicContact CD1-CB 4.46Å; S151-A155 WeakPolarHBondContact O-CB 3.22Å; S151-A155 PolarHBondContact O-N 3.22Å; V152-A155 PolarHBondContact O-N 3.37Å; V152-A155 VanDerWaalsContact O-N 3.12Å; A155-Y165 PolarHBondContact O-OH 2.99Å
156	F	87.4	Confident	84.8	Confident	90 Å²	90	53.5 Å²	53.5	40%	0.395	29%	0.286	S	S	.	.	S	Bend	trans	-76.8	-36.7	-172.2	-155.8	-123.1	0	0	0	116.4	F101 V152 V159 F160	F101-F156 HydrophobicContact CE2-CD2 4.14Å; V152-F156 VanDerWaalsContact O-CB 3.28Å; V152-F156 WeakPolarHBondContact O-CB 3.27Å; V152-F156 PolarHBondContact O-N 3Å; F156-V159 HydrophobicContact CD2-CG2 4.31Å; F156-V159 WeakPolarHBondContact O-CB 3.47Å; F156-V159 WeakPolarHBondContact O-CG2 3.45Å; F156-V159 PolarHBondContact O-N 2.82Å; F156-F160 HydrophobicContact CD1-CD2 4.11Å; F156-F160 AromaticContact CD1-CE2 3.42Å; F156-F160 HydrophobicContact CD1-CE2 3.42Å; F156-F160 VanDerWaalsContact CD1-CE2 3.42Å; F156-F160 HydrophobicContact CD1-CZ 4.18Å; F156-F160 HydrophobicContact CE1-CD2 4.08Å; F156-F160 AromaticContact CE1-CE2 3.03Å; F156-F160 HydrophobicContact CE1-CE2 3.03Å; F156-F160 AromaticContact CE1-CZ 3.34Å; F156-F160 HydrophobicContact CE1-CZ 3.34Å; F156-F160 HydrophobicContact CG-CE2 4.48Å; F156-F160 AromaticContact CZ-CE2 3.81Å; F156-F160 HydrophobicContact CZ-CE2 3.81Å; F156-F160 AromaticContact CZ-CZ 3.71Å; F156-F160 HydrophobicContact CZ-CZ 3.71Å
157	P	84.3	Confident	84.3	Confident	40 Å²	40	51.8 Å²	51.8	26%	0.26	28%	0.277	S	S	.	.	G	3₁₀ helix	trans	-58.5	-37.6	-173.6	-21.2	29.6	0	0	0	115.3	A153 M154 V159 F160 V162 F189	A153-P157 WeakPolarHBondContact O-CD 3.28Å; M154-P157 WeakPolarHBondContact O-CD 3.5Å; P157-V159 PolarHBondContact O-N 3.36Å; P157-V159 VanDerWaalsContact O-N 3.12Å; P157-F160 PolarHBondContact O-N 3.49Å; P157-F160 VanDerWaalsContact O-N 3.1Å; P157-V162 HydrophobicContact CB-CB 4.49Å; P157-F189 HydrophobicContact CB-CZ 3.79Å; P157-F189 HydrophobicContact CG-CE1 4.2Å; P157-F189 HydrophobicContact CG-CZ 3.86Å
158	P	78.6	Confident	83.7	Confident	5 Å²	5	52.5 Å²	52.5	3%	0.032	28%	0.281	C	S	.	.	G	3₁₀ helix	trans	-65.9	-9.5	174.2	-21.6	33.6	0	0	0	114.9	G163 Y165 F176 F189	P158-G163 WeakPolarHBondContact CA-O 3.48Å; P158-Y165 HydrophobicContact CB-CD1 4.39Å; P158-Y165 HydrophobicContact CB-CD2 4.09Å; P158-Y165 HydrophobicContact CB-CE1 3.98Å; P158-Y165 HydrophobicContact CB-CE2 3.66Å; P158-Y165 HydrophobicContact CB-CG 4.43Å; P158-Y165 HydrophobicContact CG-CE1 4.43Å; P158-Y165 HydrophobicContact CG-CE2 4.46Å; P158-F176 HydrophobicContact CB-CD2 3.76Å; P158-F176 HydrophobicContact CB-CE2 3.71Å; P158-F176 HydrophobicContact CG-CD2 3.78Å; P158-F176 HydrophobicContact CG-CE2 3.61Å; P158-F189 HydrophobicContact CG-CE2 4.18Å; P158-F189 HydrophobicContact CG-CZ 4.19Å
159	V	78	Confident	82.9	Confident	51 Å²	51	52.1 Å²	52.1	31%	0.309	29%	0.288	S	S	.	.	G	3₁₀ helix	trans	-74.8	-31.4	172.9	-176.5	0	0	0	0	111.2	F101 F156 P157 D161 Y165	F101-V159 HydrophobicContact CD2-CG2 3.81Å; F101-V159 HydrophobicContact CE2-CG2 4.49Å; F101-V159 HydrophobicContact CG-CG2 4.47Å; F156-V159 HydrophobicContact CD2-CG2 4.31Å; F156-V159 WeakPolarHBondContact O-CB 3.47Å; F156-V159 WeakPolarHBondContact O-CG2 3.45Å; F156-V159 PolarHBondContact O-N 2.82Å; P157-V159 PolarHBondContact O-N 3.36Å; P157-V159 VanDerWaalsContact O-N 3.12Å; V159-D161 VanDerWaalsContact C-N 3.3Å; V159-D161 PolarHBondContact O-N 2.99Å; V159-Y165 HydrophobicContact CG2-CD2 4.37Å; V159-Y165 HydrophobicContact CG2-CE2 3.82Å
160	F	75.4	Confident	82.2	Confident	134 Å²	134	51.9 Å²	51.9	59%	0.588	28%	0.281	S	S	*	.	G	3₁₀ helix	trans	-93.2	26.8	177.7	-63.4	-63.4	0	0	0	113.4	F156 P157 V162	F156-F160 HydrophobicContact CD1-CD2 4.11Å; F156-F160 AromaticContact CD1-CE2 3.42Å; F156-F160 HydrophobicContact CD1-CE2 3.42Å; F156-F160 VanDerWaalsContact CD1-CE2 3.42Å; F156-F160 HydrophobicContact CD1-CZ 4.18Å; F156-F160 HydrophobicContact CE1-CD2 4.08Å; F156-F160 AromaticContact CE1-CE2 3.03Å; F156-F160 HydrophobicContact CE1-CE2 3.03Å; F156-F160 AromaticContact CE1-CZ 3.34Å; F156-F160 HydrophobicContact CE1-CZ 3.34Å; F156-F160 HydrophobicContact CG-CE2 4.48Å; F156-F160 AromaticContact CZ-CE2 3.81Å; F156-F160 HydrophobicContact CZ-CE2 3.81Å; F156-F160 AromaticContact CZ-CZ 3.71Å; F156-F160 HydrophobicContact CZ-CZ 3.71Å; P157-F160 PolarHBondContact O-N 3.49Å; P157-F160 VanDerWaalsContact O-N 3.1Å; F160-V162 PolarHBondContact O-N 2.95Å
161	D	67.5	Low	81.6	Confident	106 Å²	106	48.8 Å²	48.8	57%	0.567	26%	0.264	S	S	*	.	T	Hydrogen-bonded Turn	trans	62.7	18.5	178.6	-57	-52.6	0	0	0	115.2	K97 V159 G163	K97-D161 IonicContact NZ-OD1 3.72Å; V159-D161 VanDerWaalsContact C-N 3.3Å; V159-D161 PolarHBondContact O-N 2.99Å; D161-G163 PolarHBondContact O-N 2.9Å
162	V	58.3	Low	81	Confident	69 Å²	69	49.2 Å²	49.2	42%	0.418	27%	0.266	S	S	.	.	S	Bend	trans	-79.3	52.3	165.9	-167.4	0	0	0	0	109.9	P157 F160 D185	P157-V162 HydrophobicContact CB-CB 4.49Å; F160-V162 PolarHBondContact O-N 2.95Å; V162-D185 HydrophobicContact CG1-CB 4.22Å
163	G	59.9	Low	80.6	Confident	12 Å²	12	47 Å²	47	12%	0.124	25%	0.252	C	S	.	.	S	Bend	trans	111	141.6	-162	0	0	0	0	0	111.1	P158 D161	P158-G163 WeakPolarHBondContact CA-O 3.48Å; D161-G163 PolarHBondContact O-N 2.9Å
164	T	74.3	Confident	80.3	Confident	32 Å²	32	44.3 Å²	44.3	20%	0.196	23%	0.23	C	C	.	.			trans	-109.4	116.5	-168.5	50.4	0	0	0	0	112.6	K166 E177 R179	T164-K166 PolarHBondContact O-N 3.47Å; T164-E177 VanDerWaalsContact O-CB 3.29Å; T164-E177 WeakPolarHBondContact O-CB 3.31Å; T164-E177 PolarHBondContact O-N 2.85Å; T164-E177 VanDerWaalsContact O-N 3.17Å; T164-E177 PolarHBondContact OG1-OE2 3.48Å; T164-R179 PolarHBondContact OG1-NH2 3.21Å
165	Y	84.9	Confident	80.1	Confident	9 Å²	9	42.2 Å²	42.2	4%	0.035	22%	0.22	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-65.5	121.5	163	-72	-47.3	0	0	0	109.9	A100 F101 V104 A155 P158 V159 F176	A100-Y165 HydrophobicContact CB-CD1 3.44Å; A100-Y165 VanDerWaalsContact CB-CD1 3.44Å; A100-Y165 HydrophobicContact CB-CD2 4.37Å; A100-Y165 HydrophobicContact CB-CE1 4.06Å; A100-Y165 HydrophobicContact CB-CG 3.64Å; F101-Y165 HydrophobicContact CB-CE2 4.02Å; V104-Y165 HydrophobicContact CG2-CE1 3.94Å; A155-Y165 PolarHBondContact O-OH 2.99Å; P158-Y165 HydrophobicContact CB-CD1 4.39Å; P158-Y165 HydrophobicContact CB-CD2 4.09Å; P158-Y165 HydrophobicContact CB-CE1 3.98Å; P158-Y165 HydrophobicContact CB-CE2 3.66Å; P158-Y165 HydrophobicContact CB-CG 4.43Å; P158-Y165 HydrophobicContact CG-CE1 4.43Å; P158-Y165 HydrophobicContact CG-CE2 4.46Å; V159-Y165 HydrophobicContact CG2-CD2 4.37Å; V159-Y165 HydrophobicContact CG2-CE2 3.82Å; Y165-F176 HydrophobicContact CD1-CB 4.26Å; Y165-F176 HydrophobicContact CD1-CD2 4.37Å; Y165-F176 HydrophobicContact CE1-CB 4.15Å; Y165-F176 HydrophobicContact CE1-CD2 4.21Å
166	K	85.4	Confident	79.5	Confident	91 Å²	91	43 Å²	43	40%	0.396	22%	0.223	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-143.9	160.2	-179.9	-69.6	-166.9	-171.4	162	0	111.1	T164 T175 E177	T164-K166 PolarHBondContact O-N 3.47Å; K166-T175 PolarHBondContact N-O 3.34Å; K166-T175 PolarHBondContact O-N 3.23Å; K166-E177 VanDerWaalsContact CD-OE2 3.29Å; K166-E177 WeakPolarHBondContact CD-OE2 3.47Å; K166-E177 VanDerWaalsContact CE-OE2 3.25Å; K166-E177 WeakPolarHBondContact CE-OE2 3.5Å; K166-E177 IonicContact NZ-OE2 2.9Å; K166-E177 PolarHBondContact NZ-OE2 3.45Å
167	F	87	Confident	78.8	Confident	44 Å²	44	41 Å²	41	19%	0.193	22%	0.216	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-72.3	126.7	168.3	-178.8	-109	0	0	0	109.4	S82 S87 W89 C96 P169	S82-F167 WeakPolarHBondContact OG-CE2 3.41Å; S82-F167 VanDerWaalsContact OG-CZ 3.28Å; S82-F167 WeakPolarHBondContact OG-CZ 3.31Å; S87-F167 WeakPolarHBondContact O-CE1 3.41Å; S87-F167 WeakPolarHBondContact O-CZ 3.16Å; W89-F167 HydrophobicContact CB-CB 4.27Å; W89-F167 HydrophobicContact CB-CD1 4.3Å; W89-F167 HydrophobicContact CB-CD2 3.96Å; W89-F167 HydrophobicContact CB-CE2 4.41Å; W89-F167 HydrophobicContact CB-CG 3.89Å; W89-F167 HydrophobicContact CE3-CD2 4.13Å; W89-F167 HydrophobicContact CE3-CE2 4.39Å; C96-F167 PolarHBondContact SG-N 3.04Å; F167-P169 HydrophobicContact CD1-CG 4.16Å; F167-P169 HydrophobicContact CE1-CB 4.15Å; F167-P169 HydrophobicContact CE1-CG 3.96Å
168	V	85.4	Confident	78	Confident	16 Å²	16	40.4 Å²	40.4	10%	0.097	21%	0.209	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-110	104.2	177.3	178.7	0	0	0	0	107	E170 E171 E172 Q173 T175	V168-E170 WeakPolarHBondContact CG1-OE2 3.48Å; V168-E170 PolarHBondContact O-N 3.29Å; V168-E171 HydrophobicContact CB-CB 4.3Å; V168-E171 HydrophobicContact CG1-CB 4.15Å; V168-E171 HydrophobicContact CG1-CG 3.93Å; V168-E171 PolarHBondContact O-N 3.18Å; V168-E172 PolarHBondContact O-N 3.44Å; V168-Q173 PolarHBondContact N-O 3.42Å; V168-Q173 VanDerWaalsContact N-O 3.09Å; V168-T175 HydrophobicContact CB-CG2 4.2Å; V168-T175 HydrophobicContact CG2-CG2 3.68Å
169	P	82.6	Confident	77.3	Confident	65 Å²	65	45.1 Å²	45.1	42%	0.422	23%	0.226	S	C	.	.	G	3₁₀ helix	trans	-57.2	-34.4	-174.9	-25.5	34.3	0	0	0	113.3	F167 E171 E172	F167-P169 HydrophobicContact CD1-CG 4.16Å; F167-P169 HydrophobicContact CE1-CB 4.15Å; F167-P169 HydrophobicContact CE1-CG 3.96Å; P169-E171 VanDerWaalsContact C-N 3.27Å; P169-E171 PolarHBondContact O-N 3.32Å; P169-E172 WeakPolarHBondContact O-CG 3.4Å; P169-E172 PolarHBondContact O-N 2.94Å
170	E	81.6	Confident	76.5	Confident	85 Å²	85	47.9 Å²	47.9	40%	0.397	23%	0.232	S	C	.	.	G	3₁₀ helix	trans	-71.1	-22.9	-179.2	-53.5	80.7	-177.6	0	0	112.8	V168 L322	V168-E170 WeakPolarHBondContact CG1-OE2 3.48Å; V168-E170 PolarHBondContact O-N 3.29Å; E170-L322 HydrophobicContact CB-CD2 3.53Å; E170-L322 WeakPolarHBondContact O-CD2 3.43Å
171	E	81.5	Confident	75.6	Confident	2 Å²	2	44 Å²	44	1%	0.009	22%	0.219	C	C	.	.	G	3₁₀ helix	trans	-101.4	-6.6	174.8	-62.7	-175.6	-148.7	0	0	112.6	V168 P169 Q173 Y302 R309 L322 V326	V168-E171 HydrophobicContact CB-CB 4.3Å; V168-E171 HydrophobicContact CG1-CB 4.15Å; V168-E171 HydrophobicContact CG1-CG 3.93Å; V168-E171 PolarHBondContact O-N 3.18Å; P169-E171 VanDerWaalsContact C-N 3.27Å; P169-E171 PolarHBondContact O-N 3.32Å; E171-Q173 HydrophobicContact CB-CG 3.8Å; E171-Q173 PolarHBondContact O-N 3.01Å; E171-Q173 PolarHBondContact OE2-NE2 3.25Å; E171-Y302 WeakPolarHBondContact OE2-CE2 3.4Å; E171-Y302 PolarHBondContact OE2-OH 2.94Å; E171-R309 IonicContact OE1-CZ 3.8Å; E171-R309 IonicContact OE1-NH1 2.68Å; E171-R309 PolarHBondContact OE1-NH1 2.97Å; E171-L322 HydrophobicContact CG-CD1 4.12Å; E171-L322 HydrophobicContact CG-CD2 4.1Å; E171-L322 HydrophobicContact CG-CG 4.27Å; E171-V326 HydrophobicContact CB-CG2 4.23Å; E171-V326 HydrophobicContact CG-CG2 4.05Å
172	E	83.9	Confident	74.9	Confident	10 Å²	10	48.8 Å²	48.8	5%	0.047	24%	0.235	C	C	.	.	T	Hydrogen-bonded Turn	trans	54.1	25.5	-179.1	-59.2	171.5	150.6	0	0	113.3	K25 I83 S87 V168 P169 W327	K25-E172 VanDerWaalsContact CD-OE2 3.31Å; K25-E172 WeakPolarHBondContact CD-OE2 3.49Å; K25-E172 IonicContact NZ-OE1 2.82Å; K25-E172 PolarHBondContact NZ-OE1 3.47Å; K25-E172 IonicContact NZ-OE2 3.33Å; K25-E172 PolarHBondContact NZ-OE2 3.2Å; I83-E172 HydrophobicContact CG1-CB 4.02Å; I83-E172 HydrophobicContact CG1-CG 4.46Å; S87-E172 PolarHBondContact OG-OE1 3.09Å; V168-E172 PolarHBondContact O-N 3.44Å; P169-E172 WeakPolarHBondContact O-CG 3.4Å; P169-E172 PolarHBondContact O-N 2.94Å; E172-W327 WeakPolarHBondContact OE2-CH2 3.16Å
173	Q	87.3	Confident	74.8	Confident	13 Å²	13	47.7 Å²	47.7	6%	0.061	23%	0.231	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-142.6	155.8	-177.4	67.6	-179	-19.9	0	0	111.7	V79 V168 E171 T175 F330	V79-Q173 HydrophobicContact CG2-CB 3.97Å; V168-Q173 PolarHBondContact N-O 3.42Å; V168-Q173 VanDerWaalsContact N-O 3.09Å; E171-Q173 HydrophobicContact CB-CG 3.8Å; E171-Q173 PolarHBondContact O-N 3.01Å; E171-Q173 PolarHBondContact OE2-NE2 3.25Å; Q173-T175 HydrophobicContact CG-CG2 4.45Å; Q173-T175 PolarHBondContact O-N 3.03Å; Q173-F330 VanDerWaalsContact OE1-CZ 3.32Å
174	C	85.6	Confident	74.7	Confident	1 Å²	1	53.8 Å²	53.8	1%	0.007	26%	0.26	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-80.3	115	167.4	-71.8	0	0	0	0	109.4	W89 C96 A100	W89-C174 VanDerWaalsContact CD2-SG 3.6Å; W89-C174 VanDerWaalsContact CE3-SG 3.58Å; C96-C174 WeakPolarHBondContact CA-SG 3.19Å; C96-C174 HydrophobicContact CB-CB 4.04Å; C96-C174 WeakPolarHBondContact CB-SG 3.32Å; C96-C174 VanDerWaalsContact O-CB 3.31Å; C96-C174 WeakPolarHBondContact O-CB 3.41Å; C96-C174 WeakPolarHBondContact SG-CB 3.31Å; C96-C174 CovalentContact SG-SG 2.03Å; C96-C174 PolarHBondContact SG-SG 3.31Å; A100-C174 VanDerWaalsContact CA-O 3.31Å; A100-C174 WeakPolarHBondContact CA-O 3.39Å; A100-C174 HydrophobicContact CB-CB 4.08Å; A100-C174 WeakPolarHBondContact CB-O 3.23Å
175	T	83.3	Confident	74.1	Confident	12 Å²	12	55.1 Å²	55.1	7%	0.074	27%	0.266	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-141.3	-179.3	-178.6	-169	0	0	0	0	110.5	K166 V168 Q173	K166-T175 PolarHBondContact N-O 3.34Å; K166-T175 PolarHBondContact O-N 3.23Å; V168-T175 HydrophobicContact CB-CG2 4.2Å; V168-T175 HydrophobicContact CG2-CG2 3.68Å; Q173-T175 HydrophobicContact CG-CG2 4.45Å; Q173-T175 PolarHBondContact O-N 3.03Å
176	F	76.6	Confident	73.3	Confident	15 Å²	15	54.9 Å²	54.9	7%	0.066	27%	0.266	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-72.1	125.9	174.7	-175.2	-99.6	0	0	0	110.6	P158 Y165 H178 T186 F189	P158-F176 HydrophobicContact CB-CD2 3.76Å; P158-F176 HydrophobicContact CB-CE2 3.71Å; P158-F176 HydrophobicContact CG-CD2 3.78Å; P158-F176 HydrophobicContact CG-CE2 3.61Å; Y165-F176 HydrophobicContact CD1-CB 4.26Å; Y165-F176 HydrophobicContact CD1-CD2 4.37Å; Y165-F176 HydrophobicContact CE1-CB 4.15Å; Y165-F176 HydrophobicContact CE1-CD2 4.21Å; F176-H178 PolarHBondContact O-N 3.31Å; F176-H178 VanDerWaalsContact O-N 3.12Å; F176-T186 HydrophobicContact CD1-CG2 4.48Å; F176-T186 HydrophobicContact CE1-CG2 3.33Å; F176-T186 HydrophobicContact CZ-CG2 3.57Å; F176-F189 HydrophobicContact CZ-CD2 4.16Å
177	E	74.1	Confident	72.6	Confident	49 Å²	49	52.9 Å²	52.9	23%	0.229	26%	0.259	C	S	.	.			trans	-67.8	110.8	-179.4	-169	-171.5	157.7	0	0	110.8	T164 K166 R179	T164-E177 VanDerWaalsContact O-CB 3.29Å; T164-E177 WeakPolarHBondContact O-CB 3.31Å; T164-E177 PolarHBondContact O-N 2.85Å; T164-E177 VanDerWaalsContact O-N 3.17Å; T164-E177 PolarHBondContact OG1-OE2 3.48Å; K166-E177 VanDerWaalsContact CD-OE2 3.29Å; K166-E177 WeakPolarHBondContact CD-OE2 3.47Å; K166-E177 VanDerWaalsContact CE-OE2 3.25Å; K166-E177 WeakPolarHBondContact CE-OE2 3.5Å; K166-E177 IonicContact NZ-OE2 2.9Å; K166-E177 PolarHBondContact NZ-OE2 3.45Å; E177-R179 VanDerWaalsContact CD-NE 3.26Å; E177-R179 HydrophobicContact CG-CG 4.07Å; E177-R179 PolarHBondContact O-N 3.1Å; E177-R179 WeakPolarHBondContact OE1-CG 3.37Å; E177-R179 IonicContact OE1-CZ 2.68Å; E177-R179 IonicContact OE1-NE 3.5Å; E177-R179 PolarHBondContact OE1-NE 2.91Å; E177-R179 IonicContact OE1-NH2 3.59Å; E177-R179 IonicContact OE2-CZ 2.81Å; E177-R179 IonicContact OE2-NE 2.82Å; E177-R179 PolarHBondContact OE2-NE 3.33Å; E177-R179 IonicContact OE2-NH2 3.52Å; E177-R179 PolarHBondContact OE2-NH2 3.37Å
178	H	67.9	Low	72	Confident	27 Å²	27	52.7 Å²	52.7	13%	0.125	27%	0.27	C	S	.	.			trans	-76.9	85.5	175.7	-61.2	-66.8	0	0	0	111.1	F176 C306 R309 I310	F176-H178 PolarHBondContact O-N 3.31Å; F176-H178 VanDerWaalsContact O-N 3.12Å; H178-C306 PolarHBondContact NE2-SG 3Å; H178-R309 HydrophobicContact CB-CB 4.28Å; H178-I310 HydrophobicContact CB-CG1 4.41Å
179	R	63	Low	71.6	Confident	105 Å²	105	53.7 Å²	53.7	40%	0.396	27%	0.273	S	S	.	.			trans	-79.3	147	173.7	-68.1	-168.3	-179.4	161	20.5	112.3	T164 E177	T164-R179 PolarHBondContact OG1-NH2 3.21Å; E177-R179 VanDerWaalsContact CD-NE 3.26Å; E177-R179 HydrophobicContact CG-CG 4.07Å; E177-R179 PolarHBondContact O-N 3.1Å; E177-R179 WeakPolarHBondContact OE1-CG 3.37Å; E177-R179 IonicContact OE1-CZ 2.68Å; E177-R179 IonicContact OE1-NE 3.5Å; E177-R179 PolarHBondContact OE1-NE 2.91Å; E177-R179 IonicContact OE1-NH2 3.59Å; E177-R179 IonicContact OE2-CZ 2.81Å; E177-R179 IonicContact OE2-NE 2.82Å; E177-R179 PolarHBondContact OE2-NE 3.33Å; E177-R179 IonicContact OE2-NH2 3.52Å; E177-R179 PolarHBondContact OE2-NH2 3.37Å
180	Y	60.5	Low	71.4	Confident	108 Å²	108	51.4 Å²	51.4	42%	0.424	26%	0.257	S	S	.	.			trans	-53.4	142.3	170.8	-179.8	-105.8	0	0	0	110.8	K182 I310 R313	Y180-K182 PolarHBondContact O-N 3.09Å; Y180-I310 VanDerWaalsContact CD2-O 3.22Å; Y180-I310 WeakPolarHBondContact CD2-O 3.46Å; Y180-R313 HydrophobicContact CD2-CB 3.83Å; Y180-R313 HydrophobicContact CD2-CG 4.3Å; Y180-R313 HydrophobicContact CE2-CB 3.6Å; Y180-R313 HydrophobicContact CE2-CG 4.37Å; Y180-R313 HydrophobicContact CG-CB 4.45Å; Y180-R313 HydrophobicContact CG-CG 4.44Å
181	V	57.8	Low	71.5	Confident	54 Å²	54	51 Å²	51	33%	0.327	26%	0.257	S	S	.	.	T	Hydrogen-bonded Turn	trans	-31.4	-16.5	-170.2	-178.1	0	0	0	0	118.9	S183 I310 F311	V181-S183 PolarHBondContact O-N 2.96Å; V181-S183 VanDerWaalsContact O-N 3.14Å; V181-I310 HydrophobicContact CG2-CG2 3.88Å; V181-I310 WeakPolarHBondContact CG2-O 3.4Å; V181-I310 PolarHBondContact N-O 2.91Å; V181-F311 HydrophobicContact CG2-CD1 4.1Å
182	K	52.3	Low	71.7	Confident	205 Å²	205	52.9 Å²	52.9	89%	0.891	27%	0.266	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.5	-7.8	-174.9	-144.5	177.4	-178.7	-175.9	0	115.4	Y180	Y180-K182 PolarHBondContact O-N 3.09Å
183	S	55.6	Low	71.9	Confident	47 Å²	47	52.9 Å²	52.9	33%	0.329	27%	0.266	S	S	.	.	S	Bend	trans	-113.8	110.4	168.1	-148.7	0	0	0	0	108.3	V181 D185	V181-S183 PolarHBondContact O-N 2.96Å; V181-S183 VanDerWaalsContact O-N 3.14Å; S183-D185 PolarHBondContact O-N 2.93Å; S183-D185 PolarHBondContact OG-OD2 3.18Å
184	N	58	Low	72	Confident	139 Å²	139	54.3 Å²	54.3	74%	0.743	28%	0.276	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.6	-12.3	-174.3	-80.4	-17	0	0	0	114.5
185	D	62.1	Low	72.4	Confident	61 Å²	61	58.2 Å²	58.2	33%	0.326	30%	0.3	S	S	.	.	H	α-helix	trans	-78.2	-32.2	-168.4	-44.7	-55.8	0	0	0	113.3	V162 S183 F189	V162-D185 HydrophobicContact CG1-CB 4.22Å; S183-D185 PolarHBondContact O-N 2.93Å; S183-D185 PolarHBondContact OG-OD2 3.18Å; D185-F189 WeakPolarHBondContact O-CD2 3.37Å
186	T	66.9	Low	72.8	Confident	4 Å²	4	58.4 Å²	58.4	3%	0.025	30%	0.3	C	S	.	.	H	α-helix	trans	-77.3	-32.9	-174.9	63.4	0	0	0	0	113.5	F176	F176-T186 HydrophobicContact CD1-CG2 4.48Å; F176-T186 HydrophobicContact CE1-CG2 3.33Å; F176-T186 HydrophobicContact CZ-CG2 3.57Å
187	L	70.8	Confident	73.5	Confident	48 Å²	48	58.2 Å²	58.2	25%	0.251	30%	0.3	S	S	.	.	H	α-helix	trans	-68.4	-38.1	-178	-175.9	116.6	0	0	0	111.4	M190 L191 I310 F311	L187-M190 PolarHBondContact O-N 3.49Å; L187-L191 HydrophobicContact CD2-CD1 3.42Å; L187-L191 VanDerWaalsContact CD2-CD1 3.42Å; L187-L191 HydrophobicContact CD2-CG 4.4Å; L187-L191 HydrophobicContact CG-CD1 3.76Å; L187-L191 HydrophobicContact CG-CG 4.22Å; L187-L191 VanDerWaalsContact O-CB 3.3Å; L187-L191 WeakPolarHBondContact O-CB 3.08Å; L187-L191 VanDerWaalsContact O-CG 3.24Å; L187-L191 WeakPolarHBondContact O-CG 3.26Å; L187-L191 PolarHBondContact O-N 3.08Å; L187-I310 HydrophobicContact CD1-CG2 4.34Å; L187-F311 HydrophobicContact CD1-CE1 4.12Å; L187-F311 HydrophobicContact CD1-CZ 3.98Å
188	G	75.8	Confident	74.4	Confident	41 Å²	41	59.1 Å²	59.1	42%	0.423	31%	0.311	S	S	.	.	H	α-helix	trans	-60.3	-47.4	179.5	0	0	0	0	0	113	M190 L191 M192	G188-M190 PolarHBondContact O-N 3.2Å; G188-L191 PolarHBondContact O-N 2.93Å; G188-M192 WeakPolarHBondContact O-CB 3.45Å; G188-M192 PolarHBondContact O-N 3.41Å
189	F	75.4	Confident	75.7	Confident	36 Å²	36	60.6 Å²	60.6	16%	0.158	32%	0.322	C	S	.	.	H	α-helix	trans	-61.7	-46.2	179.6	-71.8	-70.4	0	0	0	112.6	F108 M154 P157 P158 F176 D185 M192 L193	F108-F189 HydrophobicContact CZ-CD1 4.45Å; M154-F189 WeakPolarHBondContact O-CE1 3.39Å; P157-F189 HydrophobicContact CB-CZ 3.79Å; P157-F189 HydrophobicContact CG-CE1 4.2Å; P157-F189 HydrophobicContact CG-CZ 3.86Å; P158-F189 HydrophobicContact CG-CE2 4.18Å; P158-F189 HydrophobicContact CG-CZ 4.19Å; F176-F189 HydrophobicContact CZ-CD2 4.16Å; D185-F189 WeakPolarHBondContact O-CD2 3.37Å; F189-M192 PolarHBondContact O-N 2.85Å; F189-L193 PolarHBondContact O-N 2.93Å; F189-L193 VanDerWaalsContact O-N 3.1Å
190	M	79.2	Confident	77.2	Confident	17 Å²	17	55.8 Å²	55.8	8%	0.084	31%	0.305	C	S	.	.	H	α-helix	trans	-67.9	-43.4	179.9	-66.4	-60.2	-62.8	0	0	111.6	L187 G188 M192 L193 V194 I303 C306 Y307 I310	L187-M190 PolarHBondContact O-N 3.49Å; G188-M190 PolarHBondContact O-N 3.2Å; M190-M192 VanDerWaalsContact C-N 3.31Å; M190-M192 PolarHBondContact O-N 3.41Å; M190-L193 PolarHBondContact O-N 3.17Å; M190-V194 PolarHBondContact O-N 3.11Å; M190-I303 HydrophobicContact CE-CG2 4.23Å; M190-C306 HydrophobicContact CE-CB 3.44Å; M190-C306 VanDerWaalsContact CE-CB 3.44Å; M190-C306 HydrophobicContact SD-CB 4.34Å; M190-Y307 HydrophobicContact CB-CE1 4.09Å; M190-Y307 HydrophobicContact CB-CE2 4.39Å; M190-Y307 HydrophobicContact CE-CE2 4.38Å; M190-Y307 PolarHBondContact O-OH 2.94Å; M190-Y307 VanDerWaalsContact O-OH 3.09Å; M190-I310 HydrophobicContact CB-CD1 4.5Å; M190-I310 HydrophobicContact CG-CD1 3.93Å
191	L	83.8	Confident	78.8	Confident	77 Å²	77	52.3 Å²	52.3	40%	0.403	29%	0.292	S	S	.	.	H	α-helix	trans	-60	-42.2	175.9	-77.3	175.8	0	0	0	111.8	L187 G188 V194 V195 Y307	L187-L191 HydrophobicContact CD2-CD1 3.42Å; L187-L191 VanDerWaalsContact CD2-CD1 3.42Å; L187-L191 HydrophobicContact CD2-CG 4.4Å; L187-L191 HydrophobicContact CG-CD1 3.76Å; L187-L191 HydrophobicContact CG-CG 4.22Å; L187-L191 VanDerWaalsContact O-CB 3.3Å; L187-L191 WeakPolarHBondContact O-CB 3.08Å; L187-L191 VanDerWaalsContact O-CG 3.24Å; L187-L191 WeakPolarHBondContact O-CG 3.26Å; L187-L191 PolarHBondContact O-N 3.08Å; G188-L191 PolarHBondContact O-N 2.93Å; L191-V194 PolarHBondContact O-N 3.18Å; L191-V195 WeakPolarHBondContact O-CB 3.41Å; L191-V195 VanDerWaalsContact O-CG2 3.25Å; L191-V195 WeakPolarHBondContact O-CG2 3.37Å; L191-V195 PolarHBondContact O-N 3.41Å; L191-Y307 WeakPolarHBondContact CA-OH 3.46Å; L191-Y307 PolarHBondContact N-OH 3.33Å
192	M	86.4	Confident	80.5	Confident	41 Å²	41	54 Å²	54	20%	0.202	30%	0.302	C	S	.	.	H	α-helix	trans	-62.9	-43.3	177.5	-177.9	-176.8	73.6	0	0	111.9	F108 M154 G188 F189 M190 V194 V195 I196	F108-M192 HydrophobicContact CD1-CE 3.91Å; F108-M192 HydrophobicContact CE1-CE 3.25Å; F108-M192 HydrophobicContact CE2-CE 4.47Å; F108-M192 HydrophobicContact CZ-CE 3.59Å; M154-M192 HydrophobicContact CB-CE 3.73Å; M154-M192 HydrophobicContact CE-CE 4.12Å; M154-M192 HydrophobicContact CE-SD 3.33Å; M154-M192 WeakPolarHBondContact CE-SD 3.42Å; M154-M192 HydrophobicContact CG-CE 3.38Å; M154-M192 HydrophobicContact CG-SD 3.94Å; M154-M192 HydrophobicContact SD-CE 3.38Å; M154-M192 WeakPolarHBondContact SD-CE 3.47Å; M154-M192 HydrophobicContact SD-SD 3.32Å; G188-M192 WeakPolarHBondContact O-CB 3.45Å; G188-M192 PolarHBondContact O-N 3.41Å; F189-M192 PolarHBondContact O-N 2.85Å; M190-M192 VanDerWaalsContact C-N 3.31Å; M190-M192 PolarHBondContact O-N 3.41Å; M192-V194 VanDerWaalsContact C-N 3.34Å; M192-V194 PolarHBondContact O-N 3.47Å; M192-V195 PolarHBondContact O-N 3.22Å; M192-I196 HydrophobicContact CG-CD1 3.83Å; M192-I196 HydrophobicContact CG-CG1 4.48Å; M192-I196 WeakPolarHBondContact O-CD1 3.19Å; M192-I196 VanDerWaalsContact O-CG1 3.28Å; M192-I196 WeakPolarHBondContact O-CG1 3.21Å; M192-I196 PolarHBondContact O-N 2.91Å
193	L	87.2	Confident	82.6	Confident	10 Å²	10	45.8 Å²	45.8	5%	0.052	27%	0.269	C	S	.	.	H	α-helix	trans	-59.1	-45.9	175.5	-175.7	65	0	0	0	111.1	F108 A111 F189 M190 V195 I196 V197 I303	F108-L193 HydrophobicContact CD1-CD1 4.26Å; F108-L193 HydrophobicContact CE1-CB 4.11Å; F108-L193 HydrophobicContact CE1-CD1 4.1Å; A111-L193 HydrophobicContact CB-CD1 3.9Å; F189-L193 PolarHBondContact O-N 2.93Å; F189-L193 VanDerWaalsContact O-N 3.1Å; M190-L193 PolarHBondContact O-N 3.17Å; L193-V195 PolarHBondContact O-N 3.18Å; L193-I196 PolarHBondContact O-N 3.43Å; L193-V197 VanDerWaalsContact O-CG2 3.29Å; L193-V197 WeakPolarHBondContact O-CG2 3.36Å; L193-V197 PolarHBondContact O-N 2.85Å; L193-I303 HydrophobicContact CD2-CD1 4.11Å; L193-I303 HydrophobicContact CD2-CG1 4.34Å
194	V	90.1	Very high	84.3	Confident	43 Å²	43	43.6 Å²	43.6	26%	0.261	25%	0.254	S	S	.	.	H	α-helix	trans	-60.4	-45.4	175.3	171.3	0	0	0	0	111.5	M190 L191 M192 I196 V197 C198 I303 Y307	M190-V194 PolarHBondContact O-N 3.11Å; L191-V194 PolarHBondContact O-N 3.18Å; M192-V194 VanDerWaalsContact C-N 3.34Å; M192-V194 PolarHBondContact O-N 3.47Å; V194-I196 PolarHBondContact O-N 3.44Å; V194-V197 PolarHBondContact O-N 2.88Å; V194-C198 VanDerWaalsContact O-CB 3.29Å; V194-C198 WeakPolarHBondContact O-CB 3.48Å; V194-C198 PolarHBondContact O-N 3.1Å; V194-C198 PolarHBondContact O-SG 3.33Å; V194-I303 HydrophobicContact CG2-CG2 4.05Å; V194-Y307 HydrophobicContact CG2-CE2 3.54Å; V194-Y307 VanDerWaalsContact CG2-OH 3.27Å; V194-Y307 WeakPolarHBondContact CG2-OH 3.35Å
195	V	92.4	Very high	85.9	Confident	84 Å²	84	40.9 Å²	40.9	51%	0.509	24%	0.242	S	C	.	.	H	α-helix	trans	-59.9	-45.1	178.3	168.6	0	0	0	0	110.9	L191 M192 L193 V197 C198 T199	L191-V195 WeakPolarHBondContact O-CB 3.41Å; L191-V195 VanDerWaalsContact O-CG2 3.25Å; L191-V195 WeakPolarHBondContact O-CG2 3.37Å; L191-V195 PolarHBondContact O-N 3.41Å; M192-V195 PolarHBondContact O-N 3.22Å; L193-V195 PolarHBondContact O-N 3.18Å; V195-V197 PolarHBondContact O-N 2.92Å; V195-C198 PolarHBondContact O-N 2.73Å; V195-T199 HydrophobicContact CG1-CG2 4.26Å; V195-T199 WeakPolarHBondContact O-CB 3.32Å; V195-T199 VanDerWaalsContact O-CG2 3.28Å; V195-T199 WeakPolarHBondContact O-CG2 3.35Å; V195-T199 PolarHBondContact O-N 2.98Å; V195-T199 PolarHBondContact O-OG1 3.36Å
196	I	93.6	Very high	87.4	Confident	15 Å²	15	44.7 Å²	44.7	8%	0.077	26%	0.256	C	S	.	.	H	α-helix	trans	-63.1	-45.1	178.1	-65.8	158.9	0	0	0	110.6	A111 F112 F115 M192 L193 V194 T199 T200	A111-I196 HydrophobicContact CB-CG2 4.08Å; F112-I196 HydrophobicContact CD1-CD1 3.96Å; F112-I196 HydrophobicContact CD1-CG1 4.41Å; F112-I196 HydrophobicContact CD1-CG2 4.35Å; F112-I196 HydrophobicContact CE1-CD1 3.27Å; F112-I196 HydrophobicContact CE1-CG1 3.89Å; F112-I196 HydrophobicContact CE2-CD1 4.23Å; F112-I196 HydrophobicContact CZ-CD1 3.43Å; F112-I196 VanDerWaalsContact CZ-CD1 3.43Å; F112-I196 HydrophobicContact CZ-CG1 4.49Å; F115-I196 HydrophobicContact CB-CG2 4.36Å; M192-I196 HydrophobicContact CG-CD1 3.83Å; M192-I196 HydrophobicContact CG-CG1 4.48Å; M192-I196 WeakPolarHBondContact O-CD1 3.19Å; M192-I196 VanDerWaalsContact O-CG1 3.28Å; M192-I196 WeakPolarHBondContact O-CG1 3.21Å; M192-I196 PolarHBondContact O-N 2.91Å; L193-I196 PolarHBondContact O-N 3.43Å; V194-I196 PolarHBondContact O-N 3.44Å; I196-T199 WeakPolarHBondContact CA-OG1 3.27Å; I196-T199 PolarHBondContact O-OG1 2.85Å; I196-T200 WeakPolarHBondContact O-CB 3.19Å; I196-T200 PolarHBondContact O-N 3.24Å; I196-T200 PolarHBondContact O-OG1 3.48Å
197	V	91.4	Very high	88.5	Confident	12 Å²	12	44.7 Å²	44.7	7%	0.073	26%	0.255	C	S	.	.	H	α-helix	trans	-63.5	-48.7	178.2	173.4	0	0	0	0	110.7	L193 V194 V195 T200 H201 F295 L296	L193-V197 VanDerWaalsContact O-CG2 3.29Å; L193-V197 WeakPolarHBondContact O-CG2 3.36Å; L193-V197 PolarHBondContact O-N 2.85Å; V194-V197 PolarHBondContact O-N 2.88Å; V195-V197 PolarHBondContact O-N 2.92Å; V197-T200 WeakPolarHBondContact O-CB 3.29Å; V197-T200 PolarHBondContact O-N 3.16Å; V197-H201 PolarHBondContact O-N 3.06Å; V197-H201 PolarHBondContact O-ND1 3.11Å; V197-F295 HydrophobicContact CG2-CD1 4.37Å; V197-F295 HydrophobicContact CG2-CE1 3.69Å; V197-L296 HydrophobicContact CG1-CD1 3.75Å
198	C	92.7	Very high	89.5	Confident	68 Å²	68	46 Å²	46	46%	0.459	26%	0.262	S	S	.	.	H	α-helix	trans	-61.1	-46.9	178.6	-72.1	0	0	0	0	112	V194 V195 T200 H201 V202	V194-C198 VanDerWaalsContact O-CB 3.29Å; V194-C198 WeakPolarHBondContact O-CB 3.48Å; V194-C198 PolarHBondContact O-N 3.1Å; V194-C198 PolarHBondContact O-SG 3.33Å; V195-C198 PolarHBondContact O-N 2.73Å; C198-T200 VanDerWaalsContact C-N 3.32Å; C198-T200 PolarHBondContact O-N 3.07Å; C198-H201 PolarHBondContact O-N 3.35Å; C198-V202 WeakPolarHBondContact O-CG2 3.44Å; C198-V202 PolarHBondContact O-N 3.05Å
199	T	94.7	Very high	90.2	Very high	58 Å²	58	47.1 Å²	47.1	36%	0.356	26%	0.263	S	S	.	.	H	α-helix	trans	-62.4	-39.6	178	52.2	0	0	0	0	111.8	V195 I196 H201 V202 V203	V195-T199 HydrophobicContact CG1-CG2 4.26Å; V195-T199 WeakPolarHBondContact O-CB 3.32Å; V195-T199 VanDerWaalsContact O-CG2 3.28Å; V195-T199 WeakPolarHBondContact O-CG2 3.35Å; V195-T199 PolarHBondContact O-N 2.98Å; V195-T199 PolarHBondContact O-OG1 3.36Å; I196-T199 WeakPolarHBondContact CA-OG1 3.27Å; I196-T199 PolarHBondContact O-OG1 2.85Å; T199-H201 VanDerWaalsContact C-N 3.34Å; T199-H201 PolarHBondContact O-N 3.09Å; T199-V202 PolarHBondContact O-N 3.5Å; T199-V203 WeakPolarHBondContact O-CG2 3.24Å; T199-V203 PolarHBondContact O-N 3.01Å
200	T	95.1	Very high	90.8	Very high	4 Å²	4	48 Å²	48	3%	0.025	27%	0.267	C	S	.	.	H	α-helix	trans	-57.7	-45.7	173.5	-57.2	0	0	0	0	111.6	L114 F115 I196 V197 C198 V203 Y204 T292	L114-T200 HydrophobicContact CB-CG2 4.47Å; F115-T200 WeakPolarHBondContact CA-OG1 3.3Å; F115-T200 WeakPolarHBondContact CB-OG1 3.49Å; I196-T200 WeakPolarHBondContact O-CB 3.19Å; I196-T200 PolarHBondContact O-N 3.24Å; I196-T200 PolarHBondContact O-OG1 3.48Å; V197-T200 WeakPolarHBondContact O-CB 3.29Å; V197-T200 PolarHBondContact O-N 3.16Å; C198-T200 VanDerWaalsContact C-N 3.32Å; C198-T200 PolarHBondContact O-N 3.07Å; T200-V203 PolarHBondContact O-N 2.9Å; T200-Y204 HydrophobicContact CG2-CD2 4Å; T200-Y204 HydrophobicContact CG2-CE2 3.86Å; T200-Y204 WeakPolarHBondContact O-CD2 3.31Å; T200-Y204 PolarHBondContact O-N 3.44Å; T200-Y204 VanDerWaalsContact O-N 3.09Å; T200-T292 HydrophobicContact CG2-CG2 3.71Å
201	H	92.6	Very high	91.2	Very high	34 Å²	34	47.7 Å²	47.7	16%	0.157	27%	0.266	C	S	.	.	H	α-helix	trans	-66.9	-38.7	178.5	-73.1	75.2	0	0	0	112	V197 C198 T199 V203 Y204 V205 L296	V197-H201 PolarHBondContact O-N 3.06Å; V197-H201 PolarHBondContact O-ND1 3.11Å; C198-H201 PolarHBondContact O-N 3.35Å; T199-H201 VanDerWaalsContact C-N 3.34Å; T199-H201 PolarHBondContact O-N 3.09Å; H201-V203 VanDerWaalsContact C-N 3.33Å; H201-V203 PolarHBondContact O-N 3.01Å; H201-Y204 PolarHBondContact O-N 3.23Å; H201-V205 VanDerWaalsContact O-CG2 3.31Å; H201-V205 WeakPolarHBondContact O-CG2 3.26Å; H201-V205 PolarHBondContact O-N 3.45Å; H201-L296 WeakPolarHBondContact NE2-CD2 3.32Å
202	V	94.6	Very high	91.4	Very high	90 Å²	90	50.3 Å²	50.3	55%	0.545	27%	0.271	S	S	.	.	H	α-helix	trans	-59.7	-42.9	174.3	170	0	0	0	0	111.3	C198 T199 V205 K206	C198-V202 WeakPolarHBondContact O-CG2 3.44Å; C198-V202 PolarHBondContact O-N 3.05Å; T199-V202 PolarHBondContact O-N 3.5Å; V202-V205 PolarHBondContact O-N 3.36Å; V202-K206 PolarHBondContact O-N 2.77Å
203	V	95.3	Very high	91.3	Very high	32 Å²	32	52.7 Å²	52.7	19%	0.194	29%	0.285	C	S	.	.	H	α-helix	trans	-62.7	-43.5	176.4	174.6	0	0	0	0	111.2	F115 S118 V119 T199 T200 H201 K206 M207	F115-V203 HydrophobicContact CE2-CG2 4.32Å; S118-V203 WeakPolarHBondContact OG-CG1 3.33Å; V119-V203 HydrophobicContact CG2-CG1 4.41Å; T199-V203 WeakPolarHBondContact O-CG2 3.24Å; T199-V203 PolarHBondContact O-N 3.01Å; T200-V203 PolarHBondContact O-N 2.9Å; H201-V203 VanDerWaalsContact C-N 3.33Å; H201-V203 PolarHBondContact O-N 3.01Å; V203-K206 PolarHBondContact O-N 2.65Å; V203-M207 PolarHBondContact O-N 3.36Å
204	Y	92.6	Very high	90.9	Very high	1 Å²	1	55.8 Å²	55.8	0%	0.004	30%	0.299	C	S	.	.	H	α-helix	trans	-64.5	-42.4	175.8	-85.2	-63.5	0	0	0	113.1	T200 H201 K206 M207 L208 F289 T292	T200-Y204 HydrophobicContact CG2-CD2 4Å; T200-Y204 HydrophobicContact CG2-CE2 3.86Å; T200-Y204 WeakPolarHBondContact O-CD2 3.31Å; T200-Y204 PolarHBondContact O-N 3.44Å; T200-Y204 VanDerWaalsContact O-N 3.09Å; H201-Y204 PolarHBondContact O-N 3.23Å; Y204-K206 VanDerWaalsContact C-N 3.32Å; Y204-K206 PolarHBondContact O-N 3.35Å; Y204-M207 HydrophobicContact CD1-CE 3.74Å; Y204-M207 HydrophobicContact CD1-SD 4.29Å; Y204-M207 HydrophobicContact CE1-CE 4.18Å; Y204-M207 HydrophobicContact CE1-SD 4.5Å; Y204-M207 WeakPolarHBondContact O-CB 3.3Å; Y204-M207 PolarHBondContact O-N 3.41Å; Y204-L208 WeakPolarHBondContact O-CG 3.02Å; Y204-L208 PolarHBondContact O-N 2.97Å; Y204-F289 HydrophobicContact CD1-CB 4.02Å; Y204-F289 AromaticContact CD1-CD2 3.93Å; Y204-F289 HydrophobicContact CD1-CD2 3.93Å; Y204-F289 HydrophobicContact CD1-CG 4.47Å; Y204-F289 HydrophobicContact CD2-CD2 4.46Å; Y204-F289 HydrophobicContact CE1-CB 4.07Å; Y204-F289 AromaticContact CG-CD2 3.83Å; Y204-F289 HydrophobicContact CG-CD2 3.83Å; Y204-T292 HydrophobicContact CD2-CG2 3.99Å; Y204-T292 HydrophobicContact CE2-CG2 3.75Å; Y204-T292 WeakPolarHBondContact CE2-OG1 3.22Å; Y204-T292 PolarHBondContact OH-OG1 2.8Å
205	V	92.3	Very high	90.2	Very high	82 Å²	82	62.2 Å²	62.2	50%	0.497	32%	0.318	S	S	.	.	H	α-helix	trans	-59.7	-45.5	175.1	170.7	0	0	0	0	109.9	H201 V202 M207 L208 C209	H201-V205 VanDerWaalsContact O-CG2 3.31Å; H201-V205 WeakPolarHBondContact O-CG2 3.26Å; H201-V205 PolarHBondContact O-N 3.45Å; V202-V205 PolarHBondContact O-N 3.36Å; V205-M207 VanDerWaalsContact C-N 3.33Å; V205-M207 PolarHBondContact O-N 3.25Å; V205-L208 PolarHBondContact O-N 3.06Å; V205-L208 VanDerWaalsContact O-N 3.14Å; V205-C209 PolarHBondContact O-N 3.03Å; V205-C209 PolarHBondContact O-SG 2.91Å; V205-C209 VanDerWaalsContact O-SG 3.32Å
206	K	92.7	Very high	88.9	Confident	141 Å²	141	64.7 Å²	64.7	61%	0.613	32%	0.322	S	S	*	.	H	α-helix	trans	-58.5	-42.4	173.8	-78.9	-147.8	166.8	-175.6	0	112.9	V202 V203 Y204 L208 C209 F210	V202-K206 PolarHBondContact O-N 2.77Å; V203-K206 PolarHBondContact O-N 2.65Å; Y204-K206 VanDerWaalsContact C-N 3.32Å; Y204-K206 PolarHBondContact O-N 3.35Å; K206-L208 PolarHBondContact O-N 3.49Å; K206-C209 PolarHBondContact O-N 3.31Å; K206-F210 WeakPolarHBondContact O-CB 3.25Å; K206-F210 PolarHBondContact O-N 3.49Å
207	M	90.7	Very high	87.2	Confident	4 Å²	4	69.2 Å²	69.2	2%	0.02	35%	0.345	C	S	.	.	H	α-helix	trans	-60.1	-44.2	174.3	-176.2	-166.7	76.8	0	0	111.9	R121 Y122 I125 V203 Y204 V205 F210 V211	R121-M207 HydrophobicContact CB-SD 3.89Å; Y122-M207 HydrophobicContact CD2-CB 4.02Å; I125-M207 HydrophobicContact CD1-CG 4.06Å; I125-M207 HydrophobicContact CD1-SD 3.84Å; V203-M207 PolarHBondContact O-N 3.36Å; Y204-M207 HydrophobicContact CD1-CE 3.74Å; Y204-M207 HydrophobicContact CD1-SD 4.29Å; Y204-M207 HydrophobicContact CE1-CE 4.18Å; Y204-M207 HydrophobicContact CE1-SD 4.5Å; Y204-M207 WeakPolarHBondContact O-CB 3.3Å; Y204-M207 PolarHBondContact O-N 3.41Å; V205-M207 VanDerWaalsContact C-N 3.33Å; V205-M207 PolarHBondContact O-N 3.25Å; M207-F210 PolarHBondContact O-N 3.31Å; M207-V211 WeakPolarHBondContact O-CG2 3.44Å; M207-V211 PolarHBondContact O-N 2.85Å
208	L	90.3	Very high	85.3	Confident	75 Å²	75	77.9 Å²	77.9	39%	0.393	38%	0.381	S	S	.	.	H	α-helix	trans	-67.2	-43.3	180	-69	174.8	0	0	0	112	Y204 V205 K206 V211 Y212 F289	Y204-L208 WeakPolarHBondContact O-CG 3.02Å; Y204-L208 PolarHBondContact O-N 2.97Å; V205-L208 PolarHBondContact O-N 3.06Å; V205-L208 VanDerWaalsContact O-N 3.14Å; K206-L208 PolarHBondContact O-N 3.49Å; L208-V211 PolarHBondContact O-N 3.43Å; L208-Y212 WeakPolarHBondContact O-CB 3.22Å; L208-Y212 PolarHBondContact O-N 3.45Å; L208-F289 HydrophobicContact CD1-CD2 4.34Å; L208-F289 HydrophobicContact CD1-CE1 4.4Å; L208-F289 HydrophobicContact CD1-CE2 3.99Å; L208-F289 HydrophobicContact CD1-CZ 4.01Å
209	C	90.6	Very high	83.5	Confident	65 Å²	65	80.2 Å²	80.2	44%	0.439	40%	0.395	S	S	.	.	H	α-helix	trans	-58.4	-48.5	173.4	-68.3	0	0	0	0	111	V205 K206 V211 Y212 D213	V205-C209 PolarHBondContact O-N 3.03Å; V205-C209 PolarHBondContact O-SG 2.91Å; V205-C209 VanDerWaalsContact O-SG 3.32Å; K206-C209 PolarHBondContact O-N 3.31Å; C209-V211 VanDerWaalsContact C-N 3.32Å; C209-V211 PolarHBondContact O-N 3.42Å; C209-Y212 WeakPolarHBondContact O-CB 3.13Å; C209-Y212 PolarHBondContact O-N 3.06Å; C209-D213 PolarHBondContact O-N 2.98Å
210	F	89.5	Confident	81.4	Confident	55 Å²	55	81.3 Å²	81.3	24%	0.241	41%	0.41	C	S	.	.	H	α-helix	trans	-56.6	-45	176.4	179.4	-92.2	0	0	0	112.2	I125 A126 K206 M207 Y212 D213 H214	I125-F210 HydrophobicContact CG2-CD1 4.09Å; I125-F210 HydrophobicContact CG2-CE1 4.11Å; A126-F210 VanDerWaalsContact CA-CE1 3.45Å; A126-F210 HydrophobicContact CB-CD1 4.14Å; A126-F210 HydrophobicContact CB-CD2 4.44Å; A126-F210 HydrophobicContact CB-CE1 3.79Å; A126-F210 HydrophobicContact CB-CE2 4.09Å; A126-F210 HydrophobicContact CB-CG 4.45Å; A126-F210 HydrophobicContact CB-CZ 3.74Å; K206-F210 WeakPolarHBondContact O-CB 3.25Å; K206-F210 PolarHBondContact O-N 3.49Å; M207-F210 PolarHBondContact O-N 3.31Å; F210-Y212 VanDerWaalsContact C-N 3.33Å; F210-Y212 PolarHBondContact O-N 3.31Å; F210-D213 PolarHBondContact O-N 3.27Å; F210-H214 AromaticContact CD1-CD2 3.81Å; F210-H214 AromaticContact CD2-CD2 3.98Å; F210-H214 AromaticContact CE1-CD2 3.33Å; F210-H214 WeakPolarHBondContact CE1-CD2 3.29Å; F210-H214 AromaticContact CE1-NE2 3.65Å; F210-H214 AromaticContact CE2-CD2 3.55Å; F210-H214 AromaticContact CE2-NE2 3.35Å; F210-H214 WeakPolarHBondContact CE2-NE2 3.33Å; F210-H214 AromaticContact CZ-CD2 3.2Å; F210-H214 WeakPolarHBondContact CZ-CD2 3.38Å; F210-H214 AromaticContact CZ-NE2 3.01Å; F210-H214 WeakPolarHBondContact CZ-NE2 3.37Å; F210-H214 WeakPolarHBondContact O-CB 3.47Å; F210-H214 PolarHBondContact O-CD2 3Å; F210-H214 PolarHBondContact O-N 2.94Å
211	V	87	Confident	78.9	Confident	11 Å²	11	89.6 Å²	89.6	7%	0.067	45%	0.449	C	S	.	.	H	α-helix	trans	-65.1	-37.7	176.8	169	0	0	0	0	111.9	I125 M207 L208 C209 R215 K282	I125-V211 HydrophobicContact CD1-CG2 4.32Å; I125-V211 HydrophobicContact CG2-CG2 3.65Å; M207-V211 WeakPolarHBondContact O-CG2 3.44Å; M207-V211 PolarHBondContact O-N 2.85Å; L208-V211 PolarHBondContact O-N 3.43Å; C209-V211 VanDerWaalsContact C-N 3.32Å; C209-V211 PolarHBondContact O-N 3.42Å; V211-R215 WeakPolarHBondContact O-CG 3.2Å; V211-R215 PolarHBondContact O-N 2.97Å; V211-K282 HydrophobicContact CG1-CD 4.45Å
212	Y	86.7	Confident	77	Confident	132 Å²	132	94 Å²	94	52%	0.518	47%	0.473	S	S	.	.	H	α-helix	trans	-66.3	-46.3	178.2	177.3	-98.4	0	0	0	111.3	L208 C209 F210 H214 R215 K216	L208-Y212 WeakPolarHBondContact O-CB 3.22Å; L208-Y212 PolarHBondContact O-N 3.45Å; C209-Y212 WeakPolarHBondContact O-CB 3.13Å; C209-Y212 PolarHBondContact O-N 3.06Å; F210-Y212 VanDerWaalsContact C-N 3.33Å; F210-Y212 PolarHBondContact O-N 3.31Å; Y212-H214 VanDerWaalsContact C-N 3.34Å; Y212-H214 PolarHBondContact O-N 2.81Å; Y212-R215 WeakPolarHBondContact O-CB 3.34Å; Y212-R215 PolarHBondContact O-N 2.9Å; Y212-R215 VanDerWaalsContact O-N 3.07Å; Y212-K216 HydrophobicContact CE1-CD 4.25Å; Y212-K216 PolarHBondContact O-N 3.47Å; Y212-K216 WeakPolarHBondContact OH-CE 3.35Å; Y212-K216 PolarHBondContact OH-NZ 3.27Å
213	D	84.4	Confident	74.7	Confident	90 Å²	90	94.8 Å²	94.8	48%	0.481	48%	0.478	S	S	.	.	H	α-helix	trans	-62.9	-41	177.8	-66.6	-21.9	0	0	0	111.5	C209 F210 R215 K216	C209-D213 PolarHBondContact O-N 2.98Å; F210-D213 PolarHBondContact O-N 3.27Å; D213-R215 VanDerWaalsContact C-N 3.26Å; D213-R215 PolarHBondContact O-N 3.49Å; D213-K216 WeakPolarHBondContact O-CB 3.27Å; D213-K216 PolarHBondContact O-N 3.01Å; D213-K216 VanDerWaalsContact O-N 3.09Å
214	H	79.7	Confident	72.6	Confident	76 Å²	76	98 Å²	98	35%	0.352	50%	0.5	S	S	.	.	H	α-helix	trans	-65.7	-21.9	174.4	-91.8	-75.7	0	0	0	114.7	F210 Y212 M217	F210-H214 AromaticContact CD1-CD2 3.81Å; F210-H214 AromaticContact CD2-CD2 3.98Å; F210-H214 AromaticContact CE1-CD2 3.33Å; F210-H214 WeakPolarHBondContact CE1-CD2 3.29Å; F210-H214 AromaticContact CE1-NE2 3.65Å; F210-H214 AromaticContact CE2-CD2 3.55Å; F210-H214 AromaticContact CE2-NE2 3.35Å; F210-H214 WeakPolarHBondContact CE2-NE2 3.33Å; F210-H214 AromaticContact CZ-CD2 3.2Å; F210-H214 WeakPolarHBondContact CZ-CD2 3.38Å; F210-H214 AromaticContact CZ-NE2 3.01Å; F210-H214 WeakPolarHBondContact CZ-NE2 3.37Å; F210-H214 WeakPolarHBondContact O-CB 3.47Å; F210-H214 PolarHBondContact O-CD2 3Å; F210-H214 PolarHBondContact O-N 2.94Å; Y212-H214 VanDerWaalsContact C-N 3.34Å; Y212-H214 PolarHBondContact O-N 2.81Å; H214-M217 HydrophobicContact CB-CE 4.49Å; H214-M217 WeakPolarHBondContact CE1-CE 3.37Å; H214-M217 WeakPolarHBondContact ND1-CE 3.37Å; H214-M217 PolarHBondContact ND1-SD 2.88Å; H214-M217 VanDerWaalsContact ND1-SD 3.44Å
215	R	75.1	Confident	70.5	Confident	177 Å²	177	103 Å²	103	67%	0.668	54%	0.541	S	S	*	.	H	α-helix	trans	-76.5	-26.4	172.2	-72.9	-176.6	-138.7	-120.2	8.3	112.6	V211 Y212 D213 M217	V211-R215 WeakPolarHBondContact O-CG 3.2Å; V211-R215 PolarHBondContact O-N 2.97Å; Y212-R215 WeakPolarHBondContact O-CB 3.34Å; Y212-R215 PolarHBondContact O-N 2.9Å; Y212-R215 VanDerWaalsContact O-N 3.07Å; D213-R215 VanDerWaalsContact C-N 3.26Å; D213-R215 PolarHBondContact O-N 3.49Å; R215-M217 VanDerWaalsContact C-N 3.25Å; R215-M217 PolarHBondContact O-N 3.31Å
216	K	66.1	Low	68.6	Low	136 Å²	136	105.9 Å²	105.9	59%	0.591	55%	0.552	S	S	*	*	H	α-helix	trans	-74.5	-17.5	177	-69.8	-169.9	175.6	177.7	0	112.8	Y212 D213 K218	Y212-K216 HydrophobicContact CE1-CD 4.25Å; Y212-K216 PolarHBondContact O-N 3.47Å; Y212-K216 WeakPolarHBondContact OH-CE 3.35Å; Y212-K216 PolarHBondContact OH-NZ 3.27Å; D213-K216 WeakPolarHBondContact O-CB 3.27Å; D213-K216 PolarHBondContact O-N 3.01Å; D213-K216 VanDerWaalsContact O-N 3.09Å; K216-K218 PolarHBondContact O-N 3.37Å; K216-K218 VanDerWaalsContact O-N 3.14Å
217	M	57	Low	66.5	Low	111 Å²	111	101.9 Å²	101.9	55%	0.547	54%	0.542	S	S	.	.	S	Bend	trans	-65.5	114.4	173.2	-59.1	-174.2	-163.4	0	0	109.2	H214 R215	H214-M217 HydrophobicContact CB-CE 4.49Å; H214-M217 WeakPolarHBondContact CE1-CE 3.37Å; H214-M217 WeakPolarHBondContact ND1-CE 3.37Å; H214-M217 PolarHBondContact ND1-SD 2.88Å; H214-M217 VanDerWaalsContact ND1-SD 3.44Å; R215-M217 VanDerWaalsContact C-N 3.25Å; R215-M217 PolarHBondContact O-N 3.31Å
218	K	51.5	Low	64.8	Low	194 Å²	194	110.7 Å²	110.7	84%	0.843	58%	0.583	S	S	*	*			trans	-56.6	134.8	170.2	-67.5	-177.7	179.8	-177.9	0	107.8	K216 A220	K216-K218 PolarHBondContact O-N 3.37Å; K216-K218 VanDerWaalsContact O-N 3.14Å; K218-A220 PolarHBondContact O-N 3.47Å; K218-A220 VanDerWaalsContact O-N 3.11Å
219	P	55.9	Low	62.9	Low	116 Å²	116	114.1 Å²	114.1	75%	0.753	60%	0.601	S	S	*	*			trans	-54.2	126	174.6	22.2	-30.7	0	0	0	107.5	Q221	P219-Q221 PolarHBondContact O-N 2.84Å
220	A	50.7	Low	61	Low	81 Å²	81	121.3 Å²	121.3	67%	0.669	62%	0.619	S	S	*	*			trans	-52.4	111.3	179.5	0	0	0	0	0	108.1	K218 L222	K218-A220 PolarHBondContact O-N 3.47Å; K218-A220 VanDerWaalsContact O-N 3.11Å; A220-L222 VanDerWaalsContact C-N 3.26Å; A220-L222 PolarHBondContact O-N 3.49Å
221	Q	42.3	Very low	58.9	Low	179 Å²	179	124.3 Å²	124.3	84%	0.836	64%	0.642	S	S	*	*			trans	-66.3	97.4	170	-82.2	-171	-24.7	0	0	105.6	P219 V223	P219-Q221 PolarHBondContact O-N 2.84Å; Q221-V223 PolarHBondContact O-N 3.46Å
222	L	51.2	Low	57.1	Low	125 Å²	125	130.2 Å²	130.2	65%	0.654	67%	0.668	S	S	*	*			trans	-68.6	86.5	167	-76.6	143.8	0	0	0	105.7	A220	A220-L222 VanDerWaalsContact C-N 3.26Å; A220-L222 PolarHBondContact O-N 3.49Å
223	V	46.5	Very low	55.1	Low	108 Å²	108	127 Å²	127	66%	0.655	66%	0.657	S	S	*	*			trans	-60.2	122.8	163.7	-174.4	0	0	0	0	104.8	Q221 A225	Q221-V223 PolarHBondContact O-N 3.46Å; V223-A225 PolarHBondContact O-N 2.9Å
224	P	52.5	Low	53.1	Low	100 Å²	100	124.5 Å²	124.5	65%	0.649	65%	0.653	S	S	*	*			trans	-53.4	136.6	175.8	22.3	-31.4	0	0	0	107.9	I226	P224-I226 PolarHBondContact O-N 3.44Å
225	A	48.6	Very low	51.3	Low	105 Å²	105	127.8 Å²	127.8	87%	0.868	68%	0.681	S	S	*	*			trans	-62.2	102	179.2	0	0	0	0	0	108.5	V223 S227	V223-A225 PolarHBondContact O-N 2.9Å; A225-S227 PolarHBondContact O-N 3.31Å
226	I	51.5	Low	50.5	Low	143 Å²	143	121.3 Å²	121.3	73%	0.733	67%	0.67	S	S	*	*			trans	-85.6	98.2	171.5	-64.7	169.2	0	0	0	105.5	P224	P224-I226 PolarHBondContact O-N 3.44Å
227	S	48.7	Very low	49.9	Very low	57 Å²	57	119 Å²	119	40%	0.399	68%	0.676	S	S	.	*			trans	-79.9	124.7	169.8	126	0	0	0	0	107.9	A225 N229 W230	A225-S227 PolarHBondContact O-N 3.31Å; S227-N229 VanDerWaalsContact C-N 3.25Å; S227-N229 PolarHBondContact OG-N 2.89Å; S227-W230 WeakPolarHBondContact OG-CA 3.46Å; S227-W230 WeakPolarHBondContact OG-CB 3.47Å; S227-W230 PolarHBondContact OG-N 3.48Å; S227-W230 PolarHBondContact OG-O 2.92Å
228	Q	55.8	Low	49.8	Very low	188 Å²	188	118.1 Å²	118.1	88%	0.879	68%	0.676	S	S	*	*	S	Bend	trans	-74.3	-17.1	171.9	-71.5	-171.9	-25.2	0	0	112.7
229	N	48.9	Very low	50.2	Low	147 Å²	147	109.5 Å²	109.5	79%	0.786	64%	0.643	S	S	*	*	S	Bend	trans	-108.2	-7.6	-169.7	-68	-0.1	0	0	0	114.8	S227	S227-N229 VanDerWaalsContact C-N 3.25Å; S227-N229 PolarHBondContact OG-N 2.89Å
230	W	50.8	Low	50.5	Low	216 Å²	216	110.2 Å²	110.2	82%	0.818	64%	0.636	S	S	*	*			trans	-123.1	104.2	174.7	-55.3	66.2	0	0	0	107.5	S227 F232	S227-W230 WeakPolarHBondContact OG-CA 3.46Å; S227-W230 WeakPolarHBondContact OG-CB 3.47Å; S227-W230 PolarHBondContact OG-N 3.48Å; S227-W230 PolarHBondContact OG-O 2.92Å; W230-F232 VanDerWaalsContact C-N 3.3Å; W230-F232 PolarHBondContact O-N 2.92Å
231	T	46.7	Very low	51	Low	118 Å²	118	108.7 Å²	108.7	72%	0.724	62%	0.623	S	S	*	*			trans	-67.6	95.6	159.7	47.8	0	0	0	0	106.8	H233	T231-H233 PolarHBondContact O-N 2.9Å
232	F	47.8	Very low	52.1	Low	136 Å²	136	100.2 Å²	100.2	60%	0.596	58%	0.584	S	S	*	*	S	Bend	trans	-66.1	95.1	165.5	-174.5	-102.9	0	0	0	107	W230 I261	W230-F232 VanDerWaalsContact C-N 3.3Å; W230-F232 PolarHBondContact O-N 2.92Å; F232-I261 HydrophobicContact CE2-CD1 3.98Å; F232-I261 HydrophobicContact CZ-CD1 3.55Å
233	H	45.8	Very low	52.7	Low	63 Å²	63	96.6 Å²	96.6	29%	0.292	57%	0.572	S	S	.	*	S	Bend	trans	66.1	119.4	-167.9	-53.4	-72.6	0	0	0	114.2	T231	T231-H233 PolarHBondContact O-N 2.9Å
234	G	42.3	Very low	53.7	Low	38 Å²	38	95.3 Å²	95.3	39%	0.392	56%	0.562	S	S	.	*			trans	-60.9	-178.6	-177	0	0	0	0	0	114.8	G236	G234-G236 PolarHBondContact O-N 2.91Å
235	P	41.8	Very low	54.4	Low	145 Å²	145	93 Å²	93	94%	0.942	54%	0.54	S	S	*	.	S	Bend	trans	-66.4	107.5	-172.6	27.9	-32.2	0	0	0	110.3
236	G	57.1	Low	55.2	Low	42 Å²	42	93 Å²	93	43%	0.433	52%	0.524	S	S	.	.	S	Bend	trans	170.9	160.4	176.9	0	0	0	0	0	114.1	G234 T238 G239	G234-G236 PolarHBondContact O-N 2.91Å; G236-T238 PolarHBondContact O-N 2.96Å; G236-G239 PolarHBondContact O-N 2.88Å; G236-G239 VanDerWaalsContact O-N 3.14Å
237	A	53.7	Low	55.8	Low	87 Å²	87	89.2 Å²	89.2	72%	0.719	52%	0.515	S	S	*	.	H	α-helix	trans	-54.7	-20.1	-178.1	0	0	0	0	0	114.6	A241	A237-A241 VanDerWaalsContact O-CB 3.3Å; A237-A241 WeakPolarHBondContact O-CB 3.08Å; A237-A241 PolarHBondContact O-N 3.05Å
238	T	56.1	Low	56.5	Low	92 Å²	92	89.7 Å²	89.7	56%	0.564	53%	0.528	S	S	*	.	H	α-helix	trans	-72.2	-33.8	179.4	44	0	0	0	0	113.8	G236 A242	G236-T238 PolarHBondContact O-N 2.96Å; T238-A242 PolarHBondContact O-N 3.02Å; T238-A242 VanDerWaalsContact O-N 3.13Å
239	G	59.5	Low	57	Low	13 Å²	13	88.6 Å²	88.6	13%	0.134	52%	0.521	C	S	.	.	H	α-helix	trans	-71.4	-42.3	175.1	0	0	0	0	0	112.1	G236 A242 A243	G236-G239 PolarHBondContact O-N 2.88Å; G236-G239 VanDerWaalsContact O-N 3.14Å; G239-A242 PolarHBondContact O-N 3.43Å; G239-A243 PolarHBondContact O-N 2.98Å
240	Q	62.1	Low	57.5	Low	132 Å²	132	83.2 Å²	83.2	62%	0.617	50%	0.5	S	S	*	.	H	α-helix	trans	-66.4	-38.7	175.9	-141.7	75.5	6.4	0	0	111.8	A243 N244	Q240-A243 PolarHBondContact O-N 3.26Å; Q240-N244 VanDerWaalsContact O-CB 3.28Å; Q240-N244 WeakPolarHBondContact O-CB 3.36Å; Q240-N244 PolarHBondContact O-N 3Å; Q240-N244 PolarHBondContact O-ND2 2.63Å
241	A	62.3	Low	57.8	Low	48 Å²	48	85.2 Å²	85.2	40%	0.397	51%	0.507	S	S	.	.	H	α-helix	trans	-62.7	-41.9	174.5	0	0	0	0	0	111.8	A237 W245	A237-A241 VanDerWaalsContact O-CB 3.3Å; A237-A241 WeakPolarHBondContact O-CB 3.08Å; A237-A241 PolarHBondContact O-N 3.05Å; A241-W245 WeakPolarHBondContact O-CB 3.27Å; A241-W245 PolarHBondContact O-N 3.01Å
242	A	64.8	Low	58.6	Low	2 Å²	2	81.6 Å²	81.6	2%	0.017	49%	0.494	C	S	.	.	H	α-helix	trans	-64.8	-43.3	174.5	0	0	0	0	0	112.2	T238 G239 W245 I246 L258	T238-A242 PolarHBondContact O-N 3.02Å; T238-A242 VanDerWaalsContact O-N 3.13Å; G239-A242 PolarHBondContact O-N 3.43Å; A242-W245 PolarHBondContact O-N 2.89Å; A242-I246 WeakPolarHBondContact O-CD1 3.41Å; A242-I246 WeakPolarHBondContact O-CG1 3.41Å; A242-I246 PolarHBondContact O-N 3.06Å; A242-L258 HydrophobicContact CB-CD1 3.83Å; A242-L258 HydrophobicContact CB-CG 4.5Å
243	A	63.8	Low	59.1	Low	49 Å²	49	81.1 Å²	81.1	41%	0.405	50%	0.504	S	S	.	.	H	α-helix	trans	-63.3	-44.5	176.2	0	0	0	0	0	112.5	G239 Q240 W245 I246 A247	G239-A243 PolarHBondContact O-N 2.98Å; Q240-A243 PolarHBondContact O-N 3.26Å; A243-W245 VanDerWaalsContact C-N 3.33Å; A243-W245 PolarHBondContact O-N 3.33Å; A243-I246 PolarHBondContact O-N 3.2Å; A243-A247 VanDerWaalsContact O-CB 3.3Å; A243-A247 WeakPolarHBondContact O-CB 3.32Å; A243-A247 PolarHBondContact O-N 3.42Å
244	N	66.3	Low	59.8	Low	81 Å²	81	81.5 Å²	81.5	43%	0.433	51%	0.511	S	S	.	.	H	α-helix	trans	-65	-36.9	175.7	-72	-13.2	0	0	0	111.7	Q240 A247 G248 F249 G250	Q240-N244 VanDerWaalsContact O-CB 3.28Å; Q240-N244 WeakPolarHBondContact O-CB 3.36Å; Q240-N244 PolarHBondContact O-N 3Å; Q240-N244 PolarHBondContact O-ND2 2.63Å; N244-A247 PolarHBondContact O-N 2.96Å; N244-G248 PolarHBondContact O-N 2.97Å; N244-F249 HydrophobicContact CB-CB 4.37Å; N244-F249 WeakPolarHBondContact O-CA 3.48Å; N244-F249 WeakPolarHBondContact O-CB 3.36Å; N244-F249 PolarHBondContact O-N 2.9Å; N244-G250 PolarHBondContact O-N 3.49Å
245	W	68.4	Low	60.8	Low	52 Å²	52	80.8 Å²	80.8	20%	0.197	50%	0.499	C	S	.	.	H	α-helix	trans	-67.7	-43.5	175.7	-161.6	99.3	0	0	0	111.5	A241 A242 A243 A247 G248 G252 T254 P255 L258	A241-W245 WeakPolarHBondContact O-CB 3.27Å; A241-W245 PolarHBondContact O-N 3.01Å; A242-W245 PolarHBondContact O-N 2.89Å; A243-W245 VanDerWaalsContact C-N 3.33Å; A243-W245 PolarHBondContact O-N 3.33Å; W245-A247 VanDerWaalsContact C-N 3.32Å; W245-A247 PolarHBondContact O-N 3.42Å; W245-G248 PolarHBondContact O-N 2.99Å; W245-G248 VanDerWaalsContact O-N 3.13Å; W245-G252 PolarHBondContact NE1-O 3.41Å; W245-T254 HydrophobicContact CH2-CG2 3.16Å; W245-T254 HydrophobicContact CZ2-CG2 3.38Å; W245-T254 HydrophobicContact CZ3-CG2 3.81Å; W245-P255 HydrophobicContact CB-CG 4.15Å; W245-P255 HydrophobicContact CG-CG 4.1Å; W245-L258 HydrophobicContact CB-CD1 4.48Å; W245-L258 HydrophobicContact CD2-CD1 4.48Å; W245-L258 HydrophobicContact CE3-CD1 3.87Å
246	I	64.9	Low	61.6	Low	104 Å²	104	79.4 Å²	79.4	53%	0.533	49%	0.49	S	S	.	.	H	α-helix	trans	-63.1	-36.4	173.3	-66.2	161.8	0	0	0	111.9	A242 A243 G248 L258	A242-I246 WeakPolarHBondContact O-CD1 3.41Å; A242-I246 WeakPolarHBondContact O-CG1 3.41Å; A242-I246 PolarHBondContact O-N 3.06Å; A243-I246 PolarHBondContact O-N 3.2Å; I246-G248 PolarHBondContact O-N 3.47Å; I246-L258 HydrophobicContact CD1-CD1 4.35Å; I246-L258 HydrophobicContact CD1-CD2 3.97Å; I246-L258 HydrophobicContact CG1-CD1 4.05Å; I246-L258 HydrophobicContact CG1-CD2 3.87Å
247	A	64.9	Low	61.7	Low	64 Å²	64	79.5 Å²	79.5	53%	0.529	48%	0.482	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.1	1.4	176.6	0	0	0	0	0	113.9	A243 N244 W245 F249	A243-A247 VanDerWaalsContact O-CB 3.3Å; A243-A247 WeakPolarHBondContact O-CB 3.32Å; A243-A247 PolarHBondContact O-N 3.42Å; N244-A247 PolarHBondContact O-N 2.96Å; W245-A247 VanDerWaalsContact C-N 3.32Å; W245-A247 PolarHBondContact O-N 3.42Å; A247-F249 HydrophobicContact CB-CD2 3.84Å; A247-F249 HydrophobicContact CB-CE2 4.11Å
248	G	62.5	Low	61.9	Low	67 Å²	67	76 Å²	76	69%	0.691	45%	0.452	S	S	*	.	T	Hydrogen-bonded Turn	trans	86.5	8	175.2	0	0	0	0	0	115.5	N244 W245 I246	N244-G248 PolarHBondContact O-N 2.97Å; W245-G248 PolarHBondContact O-N 2.99Å; W245-G248 VanDerWaalsContact O-N 3.13Å; I246-G248 PolarHBondContact O-N 3.47Å
249	F	66.6	Low	61.7	Low	165 Å²	165	76.5 Å²	76.5	72%	0.724	45%	0.454	S	S	*	.			trans	-91	-8	177.8	-64	-78.4	0	0	0	113.7	N244 A247 R251	N244-F249 HydrophobicContact CB-CB 4.37Å; N244-F249 WeakPolarHBondContact O-CA 3.48Å; N244-F249 WeakPolarHBondContact O-CB 3.36Å; N244-F249 PolarHBondContact O-N 2.9Å; A247-F249 HydrophobicContact CB-CD2 3.84Å; A247-F249 HydrophobicContact CB-CE2 4.11Å; F249-R251 PolarHBondContact O-N 3.44Å
250	G	59.5	Low	61.2	Low	33 Å²	33	79.8 Å²	79.8	34%	0.34	49%	0.488	S	S	.	.			trans	-82.6	107	179.9	0	0	0	0	0	112.7	N244 G252	N244-G250 PolarHBondContact O-N 3.49Å; G250-G252 PolarHBondContact O-N 3.1Å
251	R	56.8	Low	60.8	Low	259 Å²	259	77 Å²	77	98%	0.977	48%	0.477	S	S	*	.			trans	-93.2	86.9	167.3	-71.5	-168.1	177.3	170.2	0.5	109.6	F249	F249-R251 PolarHBondContact O-N 3.44Å
252	G	63.3	Low	60.1	Low	42 Å²	42	86 Å²	86	43%	0.433	50%	0.5	S	S	.	.	S	Bend	trans	172	172	178.8	0	0	0	0	0	112.7	W245 G250	W245-G252 PolarHBondContact NE1-O 3.41Å; G250-G252 PolarHBondContact O-N 3.1Å
253	P	59.5	Low	59.6	Low	126 Å²	126	91.2 Å²	91.2	82%	0.818	52%	0.524	S	S	*	.	S	Bend	trans	-57.1	148	176	23.4	-31.6	0	0	0	111.1
254	T	60	Low	59	Low	70 Å²	70	92.5 Å²	92.5	43%	0.429	54%	0.535	S	S	.	.	P	Polyproline II helix	trans	-48.6	126.2	179	41.8	0	0	0	0	110.3	W245	W245-T254 HydrophobicContact CH2-CG2 3.16Å; W245-T254 HydrophobicContact CZ2-CG2 3.38Å; W245-T254 HydrophobicContact CZ3-CG2 3.81Å
255	P	62.6	Low	58.2	Low	23 Å²	23	91.9 Å²	91.9	15%	0.149	54%	0.537	C	S	.	.	P	Polyproline II helix	trans	-55	142.2	175.3	-22.5	31.1	0	0	0	110.1	W245 T257 L258 V259	W245-P255 HydrophobicContact CB-CG 4.15Å; W245-P255 HydrophobicContact CG-CG 4.1Å; P255-T257 PolarHBondContact O-N 3.18Å; P255-L258 HydrophobicContact CB-CD1 4.46Å; P255-L258 HydrophobicContact CG-CD1 4.01Å; P255-L258 WeakPolarHBondContact O-CB 3.34Å; P255-L258 PolarHBondContact O-N 2.94Å; P255-V259 PolarHBondContact O-N 3.49Å
256	P	60.2	Low	57.3	Low	117 Å²	117	96.8 Å²	96.8	76%	0.76	56%	0.562	S	S	*	*	T	Hydrogen-bonded Turn	trans	-57.9	-21.5	-179.4	20	-30.5	0	0	0	113.2	L258 V259	P256-L258 VanDerWaalsContact C-N 3.28Å; P256-L258 PolarHBondContact O-N 3.49Å; P256-V259 PolarHBondContact O-N 3.34Å
257	T	58.6	Low	56.7	Low	43 Å²	43	95.4 Å²	95.4	26%	0.264	56%	0.562	S	S	.	*	T	Hydrogen-bonded Turn	trans	-69.9	-19.6	172.8	49.8	0	0	0	0	114.4	P255	P255-T257 PolarHBondContact O-N 3.18Å
258	L	56.7	Low	56.2	Low	14 Å²	14	94.4 Å²	94.4	7%	0.073	56%	0.557	C	S	.	*	T	Hydrogen-bonded Turn	trans	-99	-12.5	176.2	-91.1	147.4	0	0	0	112.7	A242 W245 I246 P255 P256 G260 I261	A242-L258 HydrophobicContact CB-CD1 3.83Å; A242-L258 HydrophobicContact CB-CG 4.5Å; W245-L258 HydrophobicContact CB-CD1 4.48Å; W245-L258 HydrophobicContact CD2-CD1 4.48Å; W245-L258 HydrophobicContact CE3-CD1 3.87Å; I246-L258 HydrophobicContact CD1-CD1 4.35Å; I246-L258 HydrophobicContact CD1-CD2 3.97Å; I246-L258 HydrophobicContact CG1-CD1 4.05Å; I246-L258 HydrophobicContact CG1-CD2 3.87Å; P255-L258 HydrophobicContact CB-CD1 4.46Å; P255-L258 HydrophobicContact CG-CD1 4.01Å; P255-L258 WeakPolarHBondContact O-CB 3.34Å; P255-L258 PolarHBondContact O-N 2.94Å; P256-L258 VanDerWaalsContact C-N 3.28Å; P256-L258 PolarHBondContact O-N 3.49Å; L258-G260 PolarHBondContact O-N 2.94Å; L258-G260 VanDerWaalsContact O-N 3.09Å; L258-I261 HydrophobicContact CD2-CB 4.45Å; L258-I261 HydrophobicContact CD2-CD1 4.48Å; L258-I261 PolarHBondContact O-N 3.45Å
259	V	52.2	Low	56	Low	103 Å²	103	96.1 Å²	96.1	62%	0.624	55%	0.551	S	S	*	*	T	Hydrogen-bonded Turn	trans	-70.6	105.4	178	178.9	0	0	0	0	108.3	P255 P256	P255-V259 PolarHBondContact O-N 3.49Å; P256-V259 PolarHBondContact O-N 3.34Å
260	G	49.6	Very low	55.8	Low	81 Å²	81	97 Å²	97	84%	0.835	55%	0.549	S	S	*	.	T	Hydrogen-bonded Turn	trans	118.1	-18.8	-174.8	0	0	0	0	0	113.8	L258 R262	L258-G260 PolarHBondContact O-N 2.94Å; L258-G260 VanDerWaalsContact O-N 3.09Å; G260-R262 PolarHBondContact O-N 3.5Å
261	I	54.3	Low	56	Low	75 Å²	75	102.6 Å²	102.6	39%	0.385	56%	0.56	S	S	.	*	S	Bend	trans	-82.9	104.3	171.1	-58.5	-179.8	0	0	0	107.5	F232 L258 Q263	F232-I261 HydrophobicContact CE2-CD1 3.98Å; F232-I261 HydrophobicContact CZ-CD1 3.55Å; L258-I261 HydrophobicContact CD2-CB 4.45Å; L258-I261 HydrophobicContact CD2-CD1 4.48Å; L258-I261 PolarHBondContact O-N 3.45Å; I261-Q263 PolarHBondContact O-N 3.06Å
262	R	47.4	Very low	56.4	Low	236 Å²	236	96.1 Å²	96.1	89%	0.891	54%	0.544	S	S	*	.			trans	-58.9	105.9	173.8	-164.1	175.3	-170.1	173.9	3.5	108.2	G260 A264	G260-R262 PolarHBondContact O-N 3.5Å; R262-A264 PolarHBondContact O-N 3.43Å
263	Q	53.6	Low	56.7	Low	112 Å²	112	99.7 Å²	99.7	52%	0.523	55%	0.553	S	S	.	*			trans	-50.8	127.5	178.6	-83.7	-174.1	-28.7	0	0	109.9	I261 S265	I261-Q263 PolarHBondContact O-N 3.06Å; Q263-S265 PolarHBondContact O-N 2.68Å
264	A	50.9	Low	57.2	Low	75 Å²	75	97 Å²	97	62%	0.62	53%	0.534	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68	17.3	172.2	0	0	0	0	0	113.3	R262 H266 S267 G268	R262-A264 PolarHBondContact O-N 3.43Å; A264-H266 PolarHBondContact O-N 3.04Å; A264-S267 WeakPolarHBondContact O-CA 3.39Å; A264-S267 VanDerWaalsContact O-CB 3.29Å; A264-S267 WeakPolarHBondContact O-CB 3.38Å; A264-S267 PolarHBondContact O-N 3.38Å; A264-G268 PolarHBondContact O-N 2.98Å
265	S	49.3	Very low	57.8	Low	69 Å²	69	98.1 Å²	98.1	48%	0.483	54%	0.537	S	S	.	.	H	α-helix	trans	-51.3	-37.2	172.2	179.8	0	0	0	0	111.2	Q263 S267 G268 N269	Q263-S265 PolarHBondContact O-N 2.68Å; S265-S267 VanDerWaalsContact C-N 3.31Å; S265-S267 PolarHBondContact O-N 3.24Å; S265-G268 PolarHBondContact O-N 3.36Å; S265-N269 PolarHBondContact O-N 3.44Å
266	H	49.1	Very low	58.4	Low	154 Å²	154	101.3 Å²	101.3	71%	0.713	55%	0.552	S	S	*	*	H	α-helix	trans	-66.3	-27.7	175.6	-135.3	-55	0	0	0	114.3	A264 R270	A264-H266 PolarHBondContact O-N 3.04Å; H266-R270 VanDerWaalsContact O-CB 3.27Å; H266-R270 WeakPolarHBondContact O-CB 3.3Å; H266-R270 PolarHBondContact O-N 2.98Å
267	S	53.2	Low	59.3	Low	76 Å²	76	100.1 Å²	100.1	53%	0.531	54%	0.536	S	S	.	.	H	α-helix	trans	-78	-41.6	177.8	174.8	0	0	0	0	111.7	A264 S265 R270 R271	A264-S267 WeakPolarHBondContact O-CA 3.39Å; A264-S267 VanDerWaalsContact O-CB 3.29Å; A264-S267 WeakPolarHBondContact O-CB 3.38Å; A264-S267 PolarHBondContact O-N 3.38Å; S265-S267 VanDerWaalsContact C-N 3.31Å; S265-S267 PolarHBondContact O-N 3.24Å; S267-R270 PolarHBondContact O-N 2.82Å; S267-R271 WeakPolarHBondContact O-CB 3.36Å; S267-R271 PolarHBondContact O-N 2.98Å
268	G	54.8	Low	60.3	Low	42 Å²	42	100.8 Å²	100.8	43%	0.433	54%	0.536	S	S	.	.	H	α-helix	trans	-61.9	-49.4	176	0	0	0	0	0	112.6	A264 S265 R270 R271 L272	A264-G268 PolarHBondContact O-N 2.98Å; S265-G268 PolarHBondContact O-N 3.36Å; G268-R270 VanDerWaalsContact C-N 3.34Å; G268-R270 PolarHBondContact O-N 3.25Å; G268-R271 PolarHBondContact O-N 3.15Å; G268-L272 PolarHBondContact O-N 2.62Å
269	N	58	Low	61.5	Low	104 Å²	104	106.6 Å²	106.6	56%	0.556	56%	0.561	S	S	*	*	H	α-helix	trans	-62.1	-41.1	177.6	-71.2	-7.1	0	0	0	111.8	S265 R271 L272 L273	S265-N269 PolarHBondContact O-N 3.44Å; N269-R271 PolarHBondContact O-N 3.42Å; N269-L272 PolarHBondContact O-N 2.87Å; N269-L273 VanDerWaalsContact O-CG 3.29Å; N269-L273 WeakPolarHBondContact O-CG 3.37Å; N269-L273 PolarHBondContact O-N 3.5Å
270	R	61.5	Low	62.9	Low	184 Å²	184	103.9 Å²	103.9	69%	0.694	54%	0.544	S	S	*	.	H	α-helix	trans	-64.7	-38.2	176.9	-170.5	174.9	178.2	179.8	0.2	112.3	H266 S267 G268 V274	H266-R270 VanDerWaalsContact O-CB 3.27Å; H266-R270 WeakPolarHBondContact O-CB 3.3Å; H266-R270 PolarHBondContact O-N 2.98Å; S267-R270 PolarHBondContact O-N 2.82Å; G268-R270 VanDerWaalsContact C-N 3.34Å; G268-R270 PolarHBondContact O-N 3.25Å; R270-V274 VanDerWaalsContact O-CG2 3.26Å; R270-V274 WeakPolarHBondContact O-CG2 3.31Å; R270-V274 PolarHBondContact O-N 2.91Å; R270-V274 VanDerWaalsContact O-N 3.09Å
271	R	64	Low	64.6	Low	150 Å²	150	100.7 Å²	100.7	57%	0.566	51%	0.507	S	S	*	.	H	α-helix	trans	-68.8	-38.4	177.5	-167.9	176	-177.8	179.2	0.5	112.1	S267 G268 N269 V274 L275	S267-R271 WeakPolarHBondContact O-CB 3.36Å; S267-R271 PolarHBondContact O-N 2.98Å; G268-R271 PolarHBondContact O-N 3.15Å; N269-R271 PolarHBondContact O-N 3.42Å; R271-V274 PolarHBondContact O-N 3.24Å; R271-L275 WeakPolarHBondContact O-CG 3.43Å; R271-L275 PolarHBondContact O-N 3.37Å; R271-L275 VanDerWaalsContact O-N 3.07Å
272	L	65.8	Low	66.1	Low	123 Å²	123	99.5 Å²	99.5	64%	0.644	50%	0.5	S	S	*	.	H	α-helix	trans	-67.5	-40.3	177.9	-161.2	139.9	0	0	0	111.5	G268 N269 L275 D276	G268-L272 PolarHBondContact O-N 2.62Å; N269-L272 PolarHBondContact O-N 2.87Å; L272-L275 PolarHBondContact O-N 2.94Å; L272-D276 PolarHBondContact O-N 2.95Å
273	L	68.9	Low	68	Low	117 Å²	117	94 Å²	94	61%	0.613	48%	0.479	S	S	*	.	H	α-helix	trans	-61.9	-45.3	173.1	-71.1	169.2	0	0	0	112.5	N269 L275 D276 E277	N269-L273 VanDerWaalsContact O-CG 3.29Å; N269-L273 WeakPolarHBondContact O-CG 3.37Å; N269-L273 PolarHBondContact O-N 3.5Å; L273-L275 VanDerWaalsContact C-N 3.31Å; L273-L275 PolarHBondContact O-N 3.2Å; L273-D276 PolarHBondContact O-N 3.3Å; L273-E277 WeakPolarHBondContact O-CB 3.28Å; L273-E277 PolarHBondContact O-N 3.1Å
274	V	71.5	Confident	69.6	Low	70 Å²	70	88.9 Å²	88.9	42%	0.424	46%	0.455	S	S	.	.	H	α-helix	trans	-63.4	-36.9	177.7	170.7	0	0	0	0	111.8	R270 R271 F278	R270-V274 VanDerWaalsContact O-CG2 3.26Å; R270-V274 WeakPolarHBondContact O-CG2 3.31Å; R270-V274 PolarHBondContact O-N 2.91Å; R270-V274 VanDerWaalsContact O-N 3.09Å; R271-V274 PolarHBondContact O-N 3.24Å; V274-F278 WeakPolarHBondContact O-CB 3.46Å; V274-F278 PolarHBondContact O-N 3.48Å
275	L	72.6	Confident	71.5	Confident	93 Å²	93	85.3 Å²	85.3	49%	0.487	43%	0.426	S	S	.	.	H	α-helix	trans	-68	-37	175.5	-74.2	170.9	0	0	0	112.3	R271 L272 L273 K279	R271-L275 WeakPolarHBondContact O-CG 3.43Å; R271-L275 PolarHBondContact O-N 3.37Å; R271-L275 VanDerWaalsContact O-N 3.07Å; L272-L275 PolarHBondContact O-N 2.94Å; L273-L275 VanDerWaalsContact C-N 3.31Å; L273-L275 PolarHBondContact O-N 3.2Å; L275-K279 WeakPolarHBondContact O-CG 3.5Å; L275-K279 PolarHBondContact O-N 2.86Å
276	D	74.3	Confident	73.4	Confident	89 Å²	89	87.9 Å²	87.9	48%	0.476	43%	0.428	S	S	.	.	H	α-helix	trans	-71.9	-39.9	177.4	-163.5	50.4	0	0	0	112.3	L272 L273 F278 K279 T280	L272-D276 PolarHBondContact O-N 2.95Å; L273-D276 PolarHBondContact O-N 3.3Å; D276-F278 VanDerWaalsContact C-N 3.34Å; D276-F278 PolarHBondContact O-N 3.41Å; D276-K279 PolarHBondContact O-N 2.88Å; D276-T280 WeakPolarHBondContact O-CB 3.29Å; D276-T280 PolarHBondContact O-N 2.94Å; D276-T280 PolarHBondContact O-OG1 3.48Å
277	E	78.8	Confident	75.5	Confident	92 Å²	92	80.6 Å²	80.6	43%	0.43	39%	0.394	S	S	.	.	H	α-helix	trans	-58.2	-46.4	171.2	-172.1	171.3	-162.8	0	0	110.7	L273 K279 T280 E281	L273-E277 WeakPolarHBondContact O-CB 3.28Å; L273-E277 PolarHBondContact O-N 3.1Å; E277-K279 PolarHBondContact O-N 3.22Å; E277-T280 WeakPolarHBondContact O-CB 3.48Å; E277-T280 PolarHBondContact O-N 2.96Å; E277-T280 VanDerWaalsContact O-N 3.15Å; E277-E281 WeakPolarHBondContact O-CG 3.23Å; E277-E281 PolarHBondContact O-N 3.37Å
278	F	79.5	Confident	77.4	Confident	58 Å²	58	77.1 Å²	77.1	25%	0.254	37%	0.369	S	S	.	.	H	α-helix	trans	-63.9	-38.5	177	-175	-115.7	0	0	0	113.7	I125 V274 D276 T280 E281 K282	I125-F278 HydrophobicContact CG2-CE2 4.08Å; I125-F278 HydrophobicContact CG2-CZ 4.47Å; V274-F278 WeakPolarHBondContact O-CB 3.46Å; V274-F278 PolarHBondContact O-N 3.48Å; D276-F278 VanDerWaalsContact C-N 3.34Å; D276-F278 PolarHBondContact O-N 3.41Å; F278-T280 VanDerWaalsContact C-N 3.31Å; F278-E281 PolarHBondContact O-N 3.29Å; F278-K282 HydrophobicContact CD1-CD 4.38Å; F278-K282 HydrophobicContact CE1-CD 4.08Å; F278-K282 HydrophobicContact CZ-CD 4.41Å; F278-K282 WeakPolarHBondContact O-CG 3.43Å; F278-K282 PolarHBondContact O-N 3.37Å
279	K	81.6	Confident	79.3	Confident	136 Å²	136	77.3 Å²	77.3	59%	0.591	36%	0.359	S	S	*	.	H	α-helix	trans	-63.5	-39.9	173.5	-76.2	173.5	-174.7	175.2	0	111.3	L275 D276 E277 K282 R283	L275-K279 WeakPolarHBondContact O-CG 3.5Å; L275-K279 PolarHBondContact O-N 2.86Å; D276-K279 PolarHBondContact O-N 2.88Å; E277-K279 PolarHBondContact O-N 3.22Å; K279-K282 PolarHBondContact O-N 3.47Å; K279-R283 PolarHBondContact O-N 3.13Å; K279-R283 VanDerWaalsContact O-N 3.1Å
280	T	82.4	Confident	81	Confident	46 Å²	46	74.2 Å²	74.2	28%	0.282	34%	0.342	S	S	.	.	H	α-helix	trans	-64.8	-47.6	177.6	-61.3	0	0	0	0	110.8	D276 E277 F278 K282 R283 I284	D276-T280 WeakPolarHBondContact O-CB 3.29Å; D276-T280 PolarHBondContact O-N 2.94Å; D276-T280 PolarHBondContact O-OG1 3.48Å; E277-T280 WeakPolarHBondContact O-CB 3.48Å; E277-T280 PolarHBondContact O-N 2.96Å; E277-T280 VanDerWaalsContact O-N 3.15Å; F278-T280 VanDerWaalsContact C-N 3.31Å; T280-K282 VanDerWaalsContact C-N 3.3Å; T280-K282 PolarHBondContact O-N 3.25Å; T280-R283 WeakPolarHBondContact O-CB 3.34Å; T280-R283 PolarHBondContact O-N 3.26Å; T280-I284 HydrophobicContact CG2-CD1 3.91Å; T280-I284 HydrophobicContact CG2-CG1 4.5Å; T280-I284 WeakPolarHBondContact O-CG1 3.38Å; T280-I284 PolarHBondContact O-N 3.14Å
281	E	85.2	Confident	82.6	Confident	13 Å²	13	65.4 Å²	65.4	6%	0.061	31%	0.309	C	S	.	.	H	α-helix	trans	-59.2	-38.5	176	-71.5	-59.4	131.5	0	0	112.4	R121 E277 F278 I284 G285	R121-E281 IonicContact CZ-OE2 3.7Å; R121-E281 IonicContact NH1-OE2 2.65Å; R121-E281 PolarHBondContact NH1-OE2 2.7Å; E277-E281 WeakPolarHBondContact O-CG 3.23Å; E277-E281 PolarHBondContact O-N 3.37Å; F278-E281 PolarHBondContact O-N 3.29Å; E281-I284 PolarHBondContact O-N 3.06Å; E281-G285 PolarHBondContact O-N 3.29Å
282	K	85.7	Confident	84	Confident	51 Å²	51	58.4 Å²	58.4	22%	0.222	28%	0.282	C	S	.	.	H	α-helix	trans	-63.8	-40.4	172.9	-79	-179.3	173.9	177.2	0	113.1	V211 F278 K279 T280 G285 K286	V211-K282 HydrophobicContact CG1-CD 4.45Å; F278-K282 HydrophobicContact CD1-CD 4.38Å; F278-K282 HydrophobicContact CE1-CD 4.08Å; F278-K282 HydrophobicContact CZ-CD 4.41Å; F278-K282 WeakPolarHBondContact O-CG 3.43Å; F278-K282 PolarHBondContact O-N 3.37Å; K279-K282 PolarHBondContact O-N 3.47Å; T280-K282 VanDerWaalsContact C-N 3.3Å; T280-K282 PolarHBondContact O-N 3.25Å; K282-G285 PolarHBondContact O-N 3.38Å; K282-K286 PolarHBondContact O-N 3.05Å
283	R	86.9	Confident	85.4	Confident	121 Å²	121	55.6 Å²	55.6	46%	0.457	27%	0.268	S	S	.	.	H	α-helix	trans	-65.3	-44.8	177.5	-172.7	-174.3	-62.7	165.8	2.4	110.6	K279 T280 K286 M287	K279-R283 PolarHBondContact O-N 3.13Å; K279-R283 VanDerWaalsContact O-N 3.1Å; T280-R283 WeakPolarHBondContact O-CB 3.34Å; T280-R283 PolarHBondContact O-N 3.26Å; R283-K286 PolarHBondContact O-N 2.95Å; R283-M287 PolarHBondContact O-N 2.73Å
284	I	88.2	Confident	86.6	Confident	4 Å²	4	51 Å²	51	2%	0.021	25%	0.246	C	C	.	.	H	α-helix	trans	-62.3	-44.1	175.6	-65.8	170	0	0	0	110.3	P57 Y58 T280 E281 K286 M287 Y288	P57-I284 HydrophobicContact CB-CG2 3.71Å; P57-I284 HydrophobicContact CG-CD1 4.26Å; P57-I284 HydrophobicContact CG-CG2 4.26Å; Y58-I284 HydrophobicContact CE2-CD1 4.4Å; T280-I284 HydrophobicContact CG2-CD1 3.91Å; T280-I284 HydrophobicContact CG2-CG1 4.5Å; T280-I284 WeakPolarHBondContact O-CG1 3.38Å; T280-I284 PolarHBondContact O-N 3.14Å; E281-I284 PolarHBondContact O-N 3.06Å; I284-K286 VanDerWaalsContact C-N 3.33Å; I284-K286 PolarHBondContact O-N 3.41Å; I284-M287 WeakPolarHBondContact O-CB 3.46Å; I284-M287 PolarHBondContact O-N 2.91Å; I284-Y288 HydrophobicContact CG2-CD2 3.8Å; I284-Y288 HydrophobicContact CG2-CE2 3.91Å; I284-Y288 WeakPolarHBondContact O-CD2 3.25Å; I284-Y288 PolarHBondContact O-N 3.45Å
285	G	89.9	Confident	87.7	Confident	0 Å²	0	47.8 Å²	47.8	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-58.7	-41.4	174.8	0	0	0	0	0	112.9	E281 K282 Y288 F289	E281-G285 PolarHBondContact O-N 3.29Å; K282-G285 PolarHBondContact O-N 3.38Å; G285-Y288 PolarHBondContact O-N 2.88Å; G285-F289 WeakPolarHBondContact O-CB 3.44Å; G285-F289 PolarHBondContact O-N 3Å
286	K	89.8	Confident	88.7	Confident	123 Å²	123	46.3 Å²	46.3	54%	0.535	22%	0.219	S	C	.	.	H	α-helix	trans	-64.4	-43.3	174.4	-178.6	178.9	175.5	178.2	0	112.2	K282 R283 I284 Y288 F289 L290	K282-K286 PolarHBondContact O-N 3.05Å; R283-K286 PolarHBondContact O-N 2.95Å; I284-K286 VanDerWaalsContact C-N 3.33Å; I284-K286 PolarHBondContact O-N 3.41Å; K286-Y288 VanDerWaalsContact C-N 3.34Å; K286-Y288 PolarHBondContact O-N 3.15Å; K286-F289 PolarHBondContact O-N 3.42Å; K286-L290 HydrophobicContact CG-CD1 4.29Å; K286-L290 WeakPolarHBondContact O-CG 3.35Å; K286-L290 PolarHBondContact O-N 3.04Å; K286-L290 VanDerWaalsContact O-N 3.07Å
287	M	93	Very high	89.6	Confident	1 Å²	1	46.4 Å²	46.4	1%	0.005	22%	0.223	C	C	.	.	H	α-helix	trans	-56.7	-50	176.6	-179.7	-169.1	84.8	0	0	110.5	L61 R283 I284 F289 L290 I291 F343 N344	L61-M287 HydrophobicContact CD2-CE 4.13Å; R283-M287 PolarHBondContact O-N 2.73Å; I284-M287 WeakPolarHBondContact O-CB 3.46Å; I284-M287 PolarHBondContact O-N 2.91Å; M287-F289 PolarHBondContact O-N 3.37Å; M287-L290 WeakPolarHBondContact O-CB 3.37Å; M287-L290 PolarHBondContact O-N 2.68Å; M287-I291 HydrophobicContact CE-CD1 4.46Å; M287-I291 HydrophobicContact CG-CD1 4.38Å; M287-I291 WeakPolarHBondContact O-CG1 3.33Å; M287-I291 PolarHBondContact O-N 2.86Å; M287-F343 HydrophobicContact CB-CB 4.26Å; M287-F343 HydrophobicContact CG-CB 4.37Å; M287-N344 HydrophobicContact SD-CB 3.93Å
288	Y	93.9	Very high	90.4	Very high	2 Å²	2	43.9 Å²	43.9	1%	0.008	21%	0.212	C	C	.	.	H	α-helix	trans	-65.2	-39.2	179	-87.2	-63.4	0	0	0	114.1	P57 L61 V117 R121 I284 G285 K286 L290 I291 T292	P57-Y288 HydrophobicContact CB-CE2 4.02Å; P57-Y288 PolarHBondContact O-OH 2.81Å; L61-Y288 WeakPolarHBondContact CA-OH 3.35Å; L61-Y288 VanDerWaalsContact CB-OH 3.27Å; L61-Y288 WeakPolarHBondContact CB-OH 3.38Å; L61-Y288 HydrophobicContact CD1-CE1 4.46Å; L61-Y288 PolarHBondContact N-OH 2.68Å; L61-Y288 VanDerWaalsContact N-OH 3.1Å; V117-Y288 HydrophobicContact CG1-CD1 3.44Å; V117-Y288 VanDerWaalsContact CG1-CD1 3.44Å; V117-Y288 HydrophobicContact CG1-CD2 4.09Å; V117-Y288 HydrophobicContact CG1-CE1 3.73Å; V117-Y288 HydrophobicContact CG1-CE2 4.33Å; V117-Y288 HydrophobicContact CG1-CG 3.6Å; V117-Y288 HydrophobicContact CG2-CE1 4.43Å; R121-Y288 HydrophobicContact CG-CD2 4.32Å; I284-Y288 HydrophobicContact CG2-CD2 3.8Å; I284-Y288 HydrophobicContact CG2-CE2 3.91Å; I284-Y288 WeakPolarHBondContact O-CD2 3.25Å; I284-Y288 PolarHBondContact O-N 3.45Å; G285-Y288 PolarHBondContact O-N 2.88Å; K286-Y288 VanDerWaalsContact C-N 3.34Å; K286-Y288 PolarHBondContact O-N 3.15Å; Y288-L290 VanDerWaalsContact C-N 3.26Å; Y288-L290 PolarHBondContact O-N 2.73Å; Y288-I291 HydrophobicContact CD1-CD1 4.08Å; Y288-I291 HydrophobicContact CE1-CD1 4.32Å; Y288-I291 WeakPolarHBondContact O-CB 3.28Å; Y288-I291 PolarHBondContact O-N 3.5Å; Y288-T292 PolarHBondContact O-N 3.32Å; Y288-T292 PolarHBondContact O-OG1 3.39Å
289	F	93.7	Very high	91	Very high	47 Å²	47	42.4 Å²	42.4	21%	0.206	21%	0.205	C	C	.	.	H	α-helix	trans	-57.2	-41.7	172.7	171.1	-105.9	0	0	0	111.9	Y204 L208 G285 K286 M287 T292 L293	Y204-F289 HydrophobicContact CD1-CB 4.02Å; Y204-F289 AromaticContact CD1-CD2 3.93Å; Y204-F289 HydrophobicContact CD1-CD2 3.93Å; Y204-F289 HydrophobicContact CD1-CG 4.47Å; Y204-F289 HydrophobicContact CD2-CD2 4.46Å; Y204-F289 HydrophobicContact CE1-CB 4.07Å; Y204-F289 AromaticContact CG-CD2 3.83Å; Y204-F289 HydrophobicContact CG-CD2 3.83Å; L208-F289 HydrophobicContact CD1-CD2 4.34Å; L208-F289 HydrophobicContact CD1-CE1 4.4Å; L208-F289 HydrophobicContact CD1-CE2 3.99Å; L208-F289 HydrophobicContact CD1-CZ 4.01Å; G285-F289 WeakPolarHBondContact O-CB 3.44Å; G285-F289 PolarHBondContact O-N 3Å; K286-F289 PolarHBondContact O-N 3.42Å; M287-F289 PolarHBondContact O-N 3.37Å; F289-T292 PolarHBondContact O-N 2.92Å; F289-L293 HydrophobicContact CE1-CD2 4.46Å; F289-L293 WeakPolarHBondContact O-CB 3.36Å; F289-L293 PolarHBondContact O-N 3.35Å
290	L	93.9	Very high	91.5	Very high	38 Å²	38	38 Å²	38	20%	0.199	19%	0.193	C	C	.	.	H	α-helix	trans	-68.1	-36.5	177.4	-68	170	0	0	0	112.4	K286 M287 Y288 L293 A294 I339 F343	K286-L290 HydrophobicContact CG-CD1 4.29Å; K286-L290 WeakPolarHBondContact O-CG 3.35Å; K286-L290 PolarHBondContact O-N 3.04Å; K286-L290 VanDerWaalsContact O-N 3.07Å; M287-L290 WeakPolarHBondContact O-CB 3.37Å; M287-L290 PolarHBondContact O-N 2.68Å; Y288-L290 VanDerWaalsContact C-N 3.26Å; Y288-L290 PolarHBondContact O-N 2.73Å; L290-L293 PolarHBondContact O-N 2.87Å; L290-A294 WeakPolarHBondContact O-CB 3.39Å; L290-A294 PolarHBondContact O-N 2.87Å; L290-I339 HydrophobicContact CB-CG2 3.78Å; L290-F343 HydrophobicContact CD1-CD1 3.61Å; L290-F343 HydrophobicContact CD1-CD2 3.53Å; L290-F343 HydrophobicContact CD1-CE1 3.47Å; L290-F343 VanDerWaalsContact CD1-CE1 3.47Å; L290-F343 HydrophobicContact CD1-CE2 3.4Å; L290-F343 VanDerWaalsContact CD1-CE2 3.4Å; L290-F343 HydrophobicContact CD1-CG 3.64Å; L290-F343 HydrophobicContact CD1-CZ 3.36Å
291	I	94.6	Very high	92	Very high	0 Å²	0	37.2 Å²	37.2	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-60.3	-48.2	172.5	-68.6	170.6	0	0	0	110.3	L61 L64 L114 M287 Y288 L293 A294 F295 N336 I339	L61-I291 HydrophobicContact CD1-CD1 4.27Å; L64-I291 HydrophobicContact CD2-CG2 4.13Å; L114-I291 HydrophobicContact CD2-CG2 3.89Å; M287-I291 HydrophobicContact CE-CD1 4.46Å; M287-I291 HydrophobicContact CG-CD1 4.38Å; M287-I291 WeakPolarHBondContact O-CG1 3.33Å; M287-I291 PolarHBondContact O-N 2.86Å; Y288-I291 HydrophobicContact CD1-CD1 4.08Å; Y288-I291 HydrophobicContact CE1-CD1 4.32Å; Y288-I291 WeakPolarHBondContact O-CB 3.28Å; Y288-I291 PolarHBondContact O-N 3.5Å; I291-L293 PolarHBondContact O-N 2.9Å; I291-A294 PolarHBondContact O-N 3.11Å; I291-F295 PolarHBondContact O-N 2.86Å; I291-N336 VanDerWaalsContact CG2-OD1 3.31Å; I291-N336 WeakPolarHBondContact CG2-OD1 3.49Å; I291-I339 HydrophobicContact CG1-CB 4.04Å; I291-I339 HydrophobicContact CG1-CD1 4.25Å; I291-I339 HydrophobicContact CG1-CG2 3.7Å
292	T	94.4	Very high	92.3	Very high	2 Å²	2	37.5 Å²	37.5	1%	0.012	19%	0.189	C	C	.	.	H	α-helix	trans	-64.1	-39	177.5	-57.4	0	0	0	0	112.6	T200 Y204 Y288 F289 F295 L296	T200-T292 HydrophobicContact CG2-CG2 3.71Å; Y204-T292 HydrophobicContact CD2-CG2 3.99Å; Y204-T292 HydrophobicContact CE2-CG2 3.75Å; Y204-T292 WeakPolarHBondContact CE2-OG1 3.22Å; Y204-T292 PolarHBondContact OH-OG1 2.8Å; Y288-T292 PolarHBondContact O-N 3.32Å; Y288-T292 PolarHBondContact O-OG1 3.39Å; F289-T292 PolarHBondContact O-N 2.92Å; T292-F295 WeakPolarHBondContact O-CB 3.3Å; T292-F295 PolarHBondContact O-N 3.38Å; T292-L296 PolarHBondContact O-N 2.91Å; T292-L296 VanDerWaalsContact O-N 3.12Å
293	L	93.9	Very high	92.4	Very high	65 Å²	65	36 Å²	36	34%	0.34	18%	0.184	S	C	.	.	H	α-helix	trans	-65.5	-40.3	176.5	-176.1	65.4	0	0	0	111.5	F289 L290 I291 F295 L296 V297	F289-L293 HydrophobicContact CE1-CD2 4.46Å; F289-L293 WeakPolarHBondContact O-CB 3.36Å; F289-L293 PolarHBondContact O-N 3.35Å; L290-L293 PolarHBondContact O-N 2.87Å; I291-L293 PolarHBondContact O-N 2.9Å; L293-F295 VanDerWaalsContact C-N 3.31Å; L293-F295 PolarHBondContact O-N 2.94Å; L293-L296 PolarHBondContact O-N 3.27Å; L293-V297 WeakPolarHBondContact O-CG2 3.14Å; L293-V297 PolarHBondContact O-N 2.99Å
294	A	94.4	Very high	92.4	Very high	19 Å²	19	32.6 Å²	32.6	16%	0.157	18%	0.178	C	C	.	.	H	α-helix	trans	-61.4	-41.5	174.8	0	0	0	0	0	111.4	L290 I291 L296 V297 L298 Q332 I339	L290-A294 WeakPolarHBondContact O-CB 3.39Å; L290-A294 PolarHBondContact O-N 2.87Å; I291-A294 PolarHBondContact O-N 3.11Å; A294-L296 VanDerWaalsContact C-N 3.35Å; A294-L296 PolarHBondContact O-N 3.16Å; A294-V297 PolarHBondContact O-N 2.96Å; A294-L298 WeakPolarHBondContact O-CB 3.49Å; A294-L298 WeakPolarHBondContact O-CG 3.29Å; A294-L298 PolarHBondContact O-N 2.98Å; A294-Q332 PolarHBondContact O-OE1 3Å; A294-I339 HydrophobicContact CB-CD1 3.55Å
295	F	94.1	Very high	92.4	Very high	3 Å²	3	32.4 Å²	32.4	1%	0.013	18%	0.178	C	C	.	.	H	α-helix	trans	-56	-48.2	173.1	-179.2	-91	0	0	0	111.6	V110 A111 L114 V197 I291 T292 L293 V297 W299 Q332	V110-F295 HydrophobicContact CG1-CD2 4.16Å; V110-F295 HydrophobicContact CG1-CE2 3.48Å; V110-F295 VanDerWaalsContact CG1-CE2 3.48Å; V110-F295 HydrophobicContact CG1-CZ 4.21Å; V110-F295 HydrophobicContact CG2-CD2 4.17Å; V110-F295 HydrophobicContact CG2-CE2 4.29Å; A111-F295 HydrophobicContact CB-CZ 4.46Å; L114-F295 HydrophobicContact CD1-CB 3.81Å; L114-F295 HydrophobicContact CD1-CD1 4.29Å; L114-F295 HydrophobicContact CD1-CD2 4.16Å; L114-F295 HydrophobicContact CD1-CG 3.81Å; V197-F295 HydrophobicContact CG2-CD1 4.37Å; V197-F295 HydrophobicContact CG2-CE1 3.69Å; I291-F295 PolarHBondContact O-N 2.86Å; T292-F295 WeakPolarHBondContact O-CB 3.3Å; T292-F295 PolarHBondContact O-N 3.38Å; L293-F295 VanDerWaalsContact C-N 3.31Å; L293-F295 PolarHBondContact O-N 2.94Å; F295-V297 PolarHBondContact O-N 3.49Å; F295-W299 AromaticContact CD2-CD1 3.48Å; F295-W299 VanDerWaalsContact CD2-CD1 3.48Å; F295-W299 HydrophobicContact CD2-CG 4.31Å; F295-W299 AromaticContact CD2-NE1 3.61Å; F295-W299 HydrophobicContact CE1-CG 4.4Å; F295-W299 AromaticContact CE2-CD1 3.43Å; F295-W299 VanDerWaalsContact CE2-CD1 3.43Å; F295-W299 HydrophobicContact CE2-CD2 4.17Å; F295-W299 AromaticContact CE2-CE2 3.81Å; F295-W299 AromaticContact CE2-CG 3.94Å; F295-W299 HydrophobicContact CE2-CG 3.94Å; F295-W299 AromaticContact CE2-NE1 3.33Å; F295-W299 VanDerWaalsContact CE2-NE1 3.33Å; F295-W299 AromaticContact CZ-CD1 3.92Å; F295-W299 HydrophobicContact CZ-CD2 4.24Å; F295-W299 AromaticContact CZ-CG 3.99Å; F295-W299 HydrophobicContact CZ-CG 3.99Å; F295-W299 VanDerWaalsContact O-CB 3.26Å; F295-W299 WeakPolarHBondContact O-CB 3.4Å; F295-W299 VanDerWaalsContact O-CD1 3.26Å; F295-W299 PolarHBondContact O-N 3.06Å; F295-Q332 HydrophobicContact CD2-CG 4.14Å
296	L	93.6	Very high	92.1	Very high	63 Å²	63	32.5 Å²	32.5	33%	0.33	18%	0.178	S	C	.	.	H	α-helix	trans	-59.8	-48.8	177.2	178.7	67.1	0	0	0	112.1	V197 H201 T292 L293 A294 L298 A300	V197-L296 HydrophobicContact CG1-CD1 3.75Å; H201-L296 WeakPolarHBondContact NE2-CD2 3.32Å; T292-L296 PolarHBondContact O-N 2.91Å; T292-L296 VanDerWaalsContact O-N 3.12Å; L293-L296 PolarHBondContact O-N 3.27Å; A294-L296 VanDerWaalsContact C-N 3.35Å; A294-L296 PolarHBondContact O-N 3.16Å; L296-L298 PolarHBondContact O-N 3.48Å; L296-A300 WeakPolarHBondContact O-CB 3.4Å; L296-A300 PolarHBondContact O-N 2.93Å
297	V	94.5	Very high	91.8	Very high	91 Å²	91	28.5 Å²	28.5	55%	0.552	16%	0.16	S	C	*	.	H	α-helix	trans	-65.2	-41.8	-175.7	171.6	0	0	0	0	111.6	L293 A294 F295 P301	L293-V297 WeakPolarHBondContact O-CG2 3.14Å; L293-V297 PolarHBondContact O-N 2.99Å; A294-V297 PolarHBondContact O-N 2.96Å; F295-V297 PolarHBondContact O-N 3.49Å; V297-P301 VanDerWaalsContact O-CD 3.29Å; V297-P301 WeakPolarHBondContact O-CD 3.18Å
298	L	94.8	Very high	91.3	Very high	38 Å²	38	32.4 Å²	32.4	20%	0.199	18%	0.18	C	C	.	.	H	α-helix	trans	-78.6	-27.7	-176.9	-71.3	172.2	0	0	0	112.9	A294 L296 M328 Q332 A335	A294-L298 WeakPolarHBondContact O-CB 3.49Å; A294-L298 WeakPolarHBondContact O-CG 3.29Å; A294-L298 PolarHBondContact O-N 2.98Å; L296-L298 PolarHBondContact O-N 3.48Å; L298-M328 HydrophobicContact CD2-CB 4.08Å; L298-M328 HydrophobicContact CD2-CG 4.27Å; L298-M328 CarbonylContact O-C 3.06Å; L298-M328 WeakPolarHBondContact O-CB 3.17Å; L298-Q332 HydrophobicContact CB-CB 4.29Å; L298-Q332 HydrophobicContact CD1-CB 4.18Å; L298-Q332 VanDerWaalsContact CD1-OE1 3.24Å; L298-A335 HydrophobicContact CD1-CB 4.3Å
299	W	92.8	Very high	90.6	Very high	28 Å²	28	35 Å²	35	11%	0.106	19%	0.19	C	C	.	.	H	α-helix	trans	-93.1	-22.8	177.4	-77	80.7	0	0	0	114.5	C107 F295 Y302 I303	C107-W299 HydrophobicContact CB-CH2 3.99Å; C107-W299 WeakPolarHBondContact SG-CH2 3.35Å; C107-W299 VanDerWaalsContact SG-CZ3 3.58Å; F295-W299 AromaticContact CD2-CD1 3.48Å; F295-W299 VanDerWaalsContact CD2-CD1 3.48Å; F295-W299 HydrophobicContact CD2-CG 4.31Å; F295-W299 AromaticContact CD2-NE1 3.61Å; F295-W299 HydrophobicContact CE1-CG 4.4Å; F295-W299 AromaticContact CE2-CD1 3.43Å; F295-W299 VanDerWaalsContact CE2-CD1 3.43Å; F295-W299 HydrophobicContact CE2-CD2 4.17Å; F295-W299 AromaticContact CE2-CE2 3.81Å; F295-W299 AromaticContact CE2-CG 3.94Å; F295-W299 HydrophobicContact CE2-CG 3.94Å; F295-W299 AromaticContact CE2-NE1 3.33Å; F295-W299 VanDerWaalsContact CE2-NE1 3.33Å; F295-W299 AromaticContact CZ-CD1 3.92Å; F295-W299 HydrophobicContact CZ-CD2 4.24Å; F295-W299 AromaticContact CZ-CG 3.99Å; F295-W299 HydrophobicContact CZ-CG 3.99Å; F295-W299 VanDerWaalsContact O-CB 3.26Å; F295-W299 WeakPolarHBondContact O-CB 3.4Å; F295-W299 VanDerWaalsContact O-CD1 3.26Å; F295-W299 PolarHBondContact O-N 3.06Å; W299-Y302 HydrophobicContact CE3-CD1 4.01Å; W299-Y302 AromaticContact CZ3-CD1 3.91Å; W299-Y302 HydrophobicContact CZ3-CD1 3.91Å; W299-Y302 HydrophobicContact CZ3-CE1 4.24Å; W299-Y302 PolarHBondContact O-N 3.49Å; W299-Y302 VanDerWaalsContact O-N 3.13Å; W299-I303 HydrophobicContact CB-CD1 4.14Å; W299-I303 WeakPolarHBondContact O-CG1 3.18Å; W299-I303 PolarHBondContact O-N 3.43Å
300	A	91.9	Very high	89.8	Confident	43 Å²	43	32.8 Å²	32.8	36%	0.355	18%	0.18	S	C	.	.	H	α-helix	trans	-55.2	-43.8	-177.2	0	0	0	0	0	113.9	L296 Y302 I303 S304	L296-A300 WeakPolarHBondContact O-CB 3.4Å; L296-A300 PolarHBondContact O-N 2.93Å; A300-Y302 VanDerWaalsContact C-N 3.33Å; A300-Y302 PolarHBondContact O-N 3.09Å; A300-I303 PolarHBondContact O-N 3.17Å; A300-S304 WeakPolarHBondContact O-CB 3.36Å; A300-S304 PolarHBondContact O-N 3.44Å; A300-S304 PolarHBondContact O-OG 3.48Å
301	P	93.4	Very high	89.1	Confident	29 Å²	29	36.3 Å²	36.3	19%	0.188	19%	0.194	C	C	.	.	H	α-helix	trans	-61.7	-40.7	177.5	-25.9	38.1	0	0	0	112.4	V297 S304 A305 A325 M328	V297-P301 VanDerWaalsContact O-CD 3.29Å; V297-P301 WeakPolarHBondContact O-CD 3.18Å; P301-S304 PolarHBondContact O-N 2.9Å; P301-S304 PolarHBondContact O-OG 2.83Å; P301-A305 PolarHBondContact O-N 3.03Å; P301-A325 HydrophobicContact CB-CB 3.94Å; P301-M328 HydrophobicContact CB-CE 3.45Å; P301-M328 VanDerWaalsContact CB-CE 3.45Å; P301-M328 HydrophobicContact CG-CE 3.39Å; P301-M328 HydrophobicContact CG-SD 3.97Å
302	Y	90.1	Very high	88.3	Confident	19 Å²	19	39.7 Å²	39.7	8%	0.075	22%	0.215	C	C	.	.	H	α-helix	trans	-65.7	-50.5	177.2	-174.2	-108	0	0	0	111.5	E171 W299 A300 S304 A305 C306 V326	E171-Y302 WeakPolarHBondContact OE2-CE2 3.4Å; E171-Y302 PolarHBondContact OE2-OH 2.94Å; W299-Y302 HydrophobicContact CE3-CD1 4.01Å; W299-Y302 AromaticContact CZ3-CD1 3.91Å; W299-Y302 HydrophobicContact CZ3-CD1 3.91Å; W299-Y302 HydrophobicContact CZ3-CE1 4.24Å; W299-Y302 PolarHBondContact O-N 3.49Å; W299-Y302 VanDerWaalsContact O-N 3.13Å; A300-Y302 VanDerWaalsContact C-N 3.33Å; A300-Y302 PolarHBondContact O-N 3.09Å; Y302-S304 VanDerWaalsContact C-N 3.25Å; Y302-S304 PolarHBondContact O-N 2.87Å; Y302-A305 WeakPolarHBondContact O-CB 3.31Å; Y302-A305 PolarHBondContact O-N 2.63Å; Y302-A305 VanDerWaalsContact O-N 3.09Å; Y302-C306 PolarHBondContact O-N 3.14Å; Y302-C306 PolarHBondContact O-SG 3.17Å; Y302-V326 HydrophobicContact CD2-CG2 4.01Å; Y302-V326 HydrophobicContact CE2-CG2 3.86Å
303	I	88.6	Confident	87.1	Confident	20 Å²	20	49.4 Å²	49.4	10%	0.103	25%	0.251	C	S	.	.	H	α-helix	trans	-57.3	-42.3	177.4	-67	172	0	0	0	110.5	M190 L193 V194 W299 A300 C306 Y307	M190-I303 HydrophobicContact CE-CG2 4.23Å; L193-I303 HydrophobicContact CD2-CD1 4.11Å; L193-I303 HydrophobicContact CD2-CG1 4.34Å; V194-I303 HydrophobicContact CG2-CG2 4.05Å; W299-I303 HydrophobicContact CB-CD1 4.14Å; W299-I303 WeakPolarHBondContact O-CG1 3.18Å; W299-I303 PolarHBondContact O-N 3.43Å; A300-I303 PolarHBondContact O-N 3.17Å; I303-C306 PolarHBondContact O-N 2.94Å; I303-Y307 HydrophobicContact CG2-CD2 3.66Å; I303-Y307 HydrophobicContact CG2-CE2 3.55Å; I303-Y307 WeakPolarHBondContact O-CD2 3.38Å; I303-Y307 PolarHBondContact O-N 3.12Å
304	S	88	Confident	85.7	Confident	49 Å²	49	49.9 Å²	49.9	34%	0.343	27%	0.272	S	S	.	.	H	α-helix	trans	-63.3	-42.2	177.4	76	0	0	0	0	112.5	A300 P301 Y302 Y307 L308	A300-S304 WeakPolarHBondContact O-CB 3.36Å; A300-S304 PolarHBondContact O-N 3.44Å; A300-S304 PolarHBondContact O-OG 3.48Å; P301-S304 PolarHBondContact O-N 2.9Å; P301-S304 PolarHBondContact O-OG 2.83Å; Y302-S304 VanDerWaalsContact C-N 3.25Å; Y302-S304 PolarHBondContact O-N 2.87Å; S304-Y307 PolarHBondContact O-N 3.4Å; S304-L308 VanDerWaalsContact O-CG 3.31Å; S304-L308 WeakPolarHBondContact O-CG 3.47Å; S304-L308 PolarHBondContact O-N 3.04Å
305	A	86.4	Confident	84.4	Confident	1 Å²	1	50.8 Å²	50.8	1%	0.008	28%	0.279	C	S	.	.	H	α-helix	trans	-63.1	-43.2	176.3	0	0	0	0	0	111.6	P301 Y302 Y307 L308 R309 L322	P301-A305 PolarHBondContact O-N 3.03Å; Y302-A305 WeakPolarHBondContact O-CB 3.31Å; Y302-A305 PolarHBondContact O-N 2.63Å; Y302-A305 VanDerWaalsContact O-N 3.09Å; A305-Y307 PolarHBondContact O-N 3.17Å; A305-L308 PolarHBondContact O-N 3.16Å; A305-R309 WeakPolarHBondContact O-CG 3.4Å; A305-R309 PolarHBondContact O-N 2.95Å; A305-L322 HydrophobicContact CB-CD1 4.38Å
306	C	83.6	Confident	83.2	Confident	1 Å²	1	56.6 Å²	56.6	1%	0.007	32%	0.317	C	S	.	.	H	α-helix	trans	-60	-44.5	175.5	-61.1	0	0	0	0	111.7	H178 M190 Y302 I303 R309 I310	H178-C306 PolarHBondContact NE2-SG 3Å; M190-C306 HydrophobicContact CE-CB 3.44Å; M190-C306 VanDerWaalsContact CE-CB 3.44Å; M190-C306 HydrophobicContact SD-CB 4.34Å; Y302-C306 PolarHBondContact O-N 3.14Å; Y302-C306 PolarHBondContact O-SG 3.17Å; I303-C306 PolarHBondContact O-N 2.94Å; C306-R309 PolarHBondContact O-N 3.44Å; C306-I310 WeakPolarHBondContact O-CD1 3.47Å; C306-I310 VanDerWaalsContact O-CG1 3.29Å; C306-I310 WeakPolarHBondContact O-CG1 3.21Å; C306-I310 PolarHBondContact O-N 3.46Å
307	Y	83.6	Confident	82.5	Confident	39 Å²	39	55 Å²	55	15%	0.153	31%	0.309	C	S	.	.	H	α-helix	trans	-66.2	-38.5	176.7	-84.9	-64.3	0	0	0	113.3	M190 L191 V194 I303 S304 A305 R309 I310 F311	M190-Y307 HydrophobicContact CB-CE1 4.09Å; M190-Y307 HydrophobicContact CB-CE2 4.39Å; M190-Y307 HydrophobicContact CE-CE2 4.38Å; M190-Y307 PolarHBondContact O-OH 2.94Å; M190-Y307 VanDerWaalsContact O-OH 3.09Å; L191-Y307 WeakPolarHBondContact CA-OH 3.46Å; L191-Y307 PolarHBondContact N-OH 3.33Å; V194-Y307 HydrophobicContact CG2-CE2 3.54Å; V194-Y307 VanDerWaalsContact CG2-OH 3.27Å; V194-Y307 WeakPolarHBondContact CG2-OH 3.35Å; I303-Y307 HydrophobicContact CG2-CD2 3.66Å; I303-Y307 HydrophobicContact CG2-CE2 3.55Å; I303-Y307 WeakPolarHBondContact O-CD2 3.38Å; I303-Y307 PolarHBondContact O-N 3.12Å; S304-Y307 PolarHBondContact O-N 3.4Å; A305-Y307 PolarHBondContact O-N 3.17Å; Y307-R309 VanDerWaalsContact C-N 3.32Å; Y307-R309 PolarHBondContact O-N 3.37Å; Y307-I310 PolarHBondContact O-N 3.12Å; Y307-F311 AromaticContact CD1-CD2 3.99Å; Y307-F311 HydrophobicContact CD1-CD2 3.99Å; Y307-F311 AromaticContact CD1-CE2 3.43Å; Y307-F311 HydrophobicContact CD1-CE2 3.43Å; Y307-F311 VanDerWaalsContact CD1-CE2 3.43Å; Y307-F311 HydrophobicContact CD1-CZ 4.41Å; Y307-F311 HydrophobicContact CE1-CE2 4.04Å; Y307-F311 HydrophobicContact CG-CE2 4.34Å; Y307-F311 VanDerWaalsContact O-CD2 3.32Å; Y307-F311 WeakPolarHBondContact O-CD2 3.38Å; Y307-F311 PolarHBondContact O-N 3.41Å
308	L	83.1	Confident	82	Confident	83 Å²	83	54.7 Å²	54.7	44%	0.435	31%	0.309	S	S	.	.	H	α-helix	trans	-60.6	-42.5	174.7	-73.4	173.1	0	0	0	111.2	S304 A305 I310 V312 I317	S304-L308 VanDerWaalsContact O-CG 3.31Å; S304-L308 WeakPolarHBondContact O-CG 3.47Å; S304-L308 PolarHBondContact O-N 3.04Å; A305-L308 PolarHBondContact O-N 3.16Å; L308-I310 VanDerWaalsContact C-N 3.31Å; L308-I310 PolarHBondContact O-N 3.28Å; L308-V312 HydrophobicContact CD2-CG2 4.45Å; L308-V312 WeakPolarHBondContact O-CB 2.93Å; L308-V312 PolarHBondContact O-N 3.44Å; L308-I317 HydrophobicContact CB-CD1 4.31Å
309	R	79	Confident	81.4	Confident	57 Å²	57	58.4 Å²	58.4	22%	0.215	33%	0.325	C	S	.	.	H	α-helix	trans	-62.1	-37.2	173.8	-70.6	-175.5	168.4	173.9	-9.4	113	E171 H178 A305 C306 Y307 I317	E171-R309 IonicContact OE1-CZ 3.8Å; E171-R309 IonicContact OE1-NH1 2.68Å; E171-R309 PolarHBondContact OE1-NH1 2.97Å; H178-R309 HydrophobicContact CB-CB 4.28Å; A305-R309 WeakPolarHBondContact O-CG 3.4Å; A305-R309 PolarHBondContact O-N 2.95Å; C306-R309 PolarHBondContact O-N 3.44Å; Y307-R309 VanDerWaalsContact C-N 3.32Å; Y307-R309 PolarHBondContact O-N 3.37Å; R309-I317 HydrophobicContact CG-CD1 3.39Å
310	I	78	Confident	81.1	Confident	0 Å²	0	63.9 Å²	63.9	0%	0	36%	0.355	C	S	.	.	H	α-helix	trans	-70.3	-51.4	179.7	-69.6	162.7	0	0	0	110.6	H178 Y180 V181 L187 M190 C306 Y307 L308	H178-I310 HydrophobicContact CB-CG1 4.41Å; Y180-I310 VanDerWaalsContact CD2-O 3.22Å; Y180-I310 WeakPolarHBondContact CD2-O 3.46Å; V181-I310 HydrophobicContact CG2-CG2 3.88Å; V181-I310 WeakPolarHBondContact CG2-O 3.4Å; V181-I310 PolarHBondContact N-O 2.91Å; L187-I310 HydrophobicContact CD1-CG2 4.34Å; M190-I310 HydrophobicContact CB-CD1 4.5Å; M190-I310 HydrophobicContact CG-CD1 3.93Å; C306-I310 WeakPolarHBondContact O-CD1 3.47Å; C306-I310 VanDerWaalsContact O-CG1 3.29Å; C306-I310 WeakPolarHBondContact O-CG1 3.21Å; C306-I310 PolarHBondContact O-N 3.46Å; Y307-I310 PolarHBondContact O-N 3.12Å; L308-I310 VanDerWaalsContact C-N 3.31Å; L308-I310 PolarHBondContact O-N 3.28Å
311	F	78.8	Confident	80.9	Confident	112 Å²	112	65.5 Å²	65.5	49%	0.491	36%	0.356	S	S	.	.	H	α-helix	trans	-86.3	-31.8	-170	-73.3	-64.9	0	0	0	114.9	V181 L187 Y307	V181-F311 HydrophobicContact CG2-CD1 4.1Å; L187-F311 HydrophobicContact CD1-CE1 4.12Å; L187-F311 HydrophobicContact CD1-CZ 3.98Å; Y307-F311 AromaticContact CD1-CD2 3.99Å; Y307-F311 HydrophobicContact CD1-CD2 3.99Å; Y307-F311 AromaticContact CD1-CE2 3.43Å; Y307-F311 HydrophobicContact CD1-CE2 3.43Å; Y307-F311 VanDerWaalsContact CD1-CE2 3.43Å; Y307-F311 HydrophobicContact CD1-CZ 4.41Å; Y307-F311 HydrophobicContact CE1-CE2 4.04Å; Y307-F311 HydrophobicContact CG-CE2 4.34Å; Y307-F311 VanDerWaalsContact O-CD2 3.32Å; Y307-F311 WeakPolarHBondContact O-CD2 3.38Å; Y307-F311 PolarHBondContact O-N 3.41Å
312	V	77.6	Confident	80.7	Confident	71 Å²	71	64.3 Å²	64.3	43%	0.43	35%	0.348	S	S	.	.	S	Bend	trans	-106.2	109.3	-175.5	-167.9	0	0	0	0	109.7	L308 G314 A315	L308-V312 HydrophobicContact CD2-CG2 4.45Å; L308-V312 WeakPolarHBondContact O-CB 2.93Å; L308-V312 PolarHBondContact O-N 3.44Å; V312-G314 PolarHBondContact O-N 3.21Å; V312-A315 HydrophobicContact CB-CB 3.79Å; V312-A315 HydrophobicContact CG1-CB 3.65Å; V312-A315 PolarHBondContact O-N 2.93Å
313	R	68.3	Low	80.6	Confident	207 Å²	207	64.8 Å²	64.8	78%	0.781	35%	0.353	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.8	117.3	179.6	-167.7	175.4	179.1	179.2	-2.2	110	Y180 A315	Y180-R313 HydrophobicContact CD2-CB 3.83Å; Y180-R313 HydrophobicContact CD2-CG 4.3Å; Y180-R313 HydrophobicContact CE2-CB 3.6Å; Y180-R313 HydrophobicContact CE2-CG 4.37Å; Y180-R313 HydrophobicContact CG-CB 4.45Å; Y180-R313 HydrophobicContact CG-CG 4.44Å; R313-A315 VanDerWaalsContact C-N 3.31Å; R313-A315 PolarHBondContact O-N 3.23Å
314	G	65.6	Low	80.7	Confident	75 Å²	75	65.9 Å²	65.9	77%	0.773	37%	0.365	S	S	*	.	T	Hydrogen-bonded Turn	trans	69.5	23.4	174.3	0	0	0	0	0	114.5	V312 P316	V312-G314 PolarHBondContact O-N 3.21Å; G314-P316 VanDerWaalsContact O-CD 3.22Å; G314-P316 WeakPolarHBondContact O-CD 3.49Å
315	A	66.4	Low	80.9	Confident	37 Å²	37	63.6 Å²	63.6	31%	0.306	35%	0.349	S	S	.	.			trans	-62.2	118.1	170.6	0	0	0	0	0	109.8	V312 R313 I317	V312-A315 HydrophobicContact CB-CB 3.79Å; V312-A315 HydrophobicContact CG1-CB 3.65Å; V312-A315 PolarHBondContact O-N 2.93Å; R313-A315 VanDerWaalsContact C-N 3.31Å; R313-A315 PolarHBondContact O-N 3.23Å; A315-I317 PolarHBondContact O-N 3.09Å
316	P	69.9	Low	81.2	Confident	125 Å²	125	63.6 Å²	63.6	81%	0.812	35%	0.348	S	S	*	.			trans	-69.4	102.9	169.4	28.8	-30.9	0	0	0	107.4	G314	G314-P316 VanDerWaalsContact O-CD 3.22Å; G314-P316 WeakPolarHBondContact O-CD 3.49Å
317	I	77.6	Confident	81.6	Confident	29 Å²	29	65.3 Å²	65.3	15%	0.149	36%	0.355	C	S	.	.			trans	-76.2	126.4	170.5	-62.9	175.4	0	0	0	106.3	L308 R309 A315 E319 H321 L322	L308-I317 HydrophobicContact CB-CD1 4.31Å; R309-I317 HydrophobicContact CG-CD1 3.39Å; A315-I317 PolarHBondContact O-N 3.09Å; I317-E319 PolarHBondContact O-N 3.47Å; I317-H321 HydrophobicContact CG2-CB 4.47Å; I317-L322 HydrophobicContact CG2-CB 4.27Å
318	P	85.3	Confident	82.2	Confident	85 Å²	85	66.4 Å²	66.4	55%	0.552	36%	0.362	S	S	*	.			trans	-54.9	127.2	175.8	-24.5	33.4	0	0	0	110.6	L320 H321 L322	P318-L320 PolarHBondContact O-N 2.99Å; P318-L320 VanDerWaalsContact O-N 3.11Å; P318-H321 HydrophobicContact CB-CB 4.27Å; P318-H321 WeakPolarHBondContact O-CB 3.45Å; P318-H321 PolarHBondContact O-N 3.38Å; P318-L322 PolarHBondContact O-N 2.95Å
319	E	82.8	Confident	82.7	Confident	117 Å²	117	62.7 Å²	62.7	55%	0.547	34%	0.343	S	S	.	.	H	α-helix	trans	-47.5	-40.7	176.9	-74.2	-70.4	148.1	0	0	112.1	I317 H321 L322 T323	I317-E319 PolarHBondContact O-N 3.47Å; E319-H321 PolarHBondContact O-N 3.29Å; E319-L322 PolarHBondContact O-N 2.81Å; E319-T323 VanDerWaalsContact O-CB 3.31Å; E319-T323 WeakPolarHBondContact O-CB 3.43Å; E319-T323 PolarHBondContact O-N 3Å; E319-T323 PolarHBondContact O-OG1 3.02Å
320	L	85.6	Confident	83.4	Confident	142 Å²	142	60.6 Å²	60.6	74%	0.743	34%	0.336	S	S	*	.	H	α-helix	trans	-62.2	-40.9	177.3	-177.1	63.6	0	0	0	112.7	P318 A324	P318-L320 PolarHBondContact O-N 2.99Å; P318-L320 VanDerWaalsContact O-N 3.11Å; L320-A324 VanDerWaalsContact O-CB 3.22Å; L320-A324 WeakPolarHBondContact O-CB 3.29Å; L320-A324 PolarHBondContact O-N 3.44Å
321	H	88.3	Confident	84.1	Confident	77 Å²	77	62.3 Å²	62.3	36%	0.356	35%	0.349	S	S	.	.	H	α-helix	trans	-68.3	-44.1	179.3	178	-82.2	0	0	0	110.9	I317 P318 E319 A324 A325	I317-H321 HydrophobicContact CG2-CB 4.47Å; P318-H321 HydrophobicContact CB-CB 4.27Å; P318-H321 WeakPolarHBondContact O-CB 3.45Å; P318-H321 PolarHBondContact O-N 3.38Å; E319-H321 PolarHBondContact O-N 3.29Å; H321-A324 PolarHBondContact O-N 3.45Å; H321-A325 VanDerWaalsContact O-CB 3.22Å; H321-A325 WeakPolarHBondContact O-CB 3.47Å; H321-A325 PolarHBondContact O-N 3.49Å
322	L	87.6	Confident	84.9	Confident	4 Å²	4	57.1 Å²	57.1	2%	0.021	33%	0.327	C	S	.	.	H	α-helix	trans	-65.3	-47.3	179.2	-176.7	71.1	0	0	0	111.5	E170 E171 A305 I317 P318 E319 A324 A325 V326	E170-L322 HydrophobicContact CB-CD2 3.53Å; E170-L322 WeakPolarHBondContact O-CD2 3.43Å; E171-L322 HydrophobicContact CG-CD1 4.12Å; E171-L322 HydrophobicContact CG-CD2 4.1Å; E171-L322 HydrophobicContact CG-CG 4.27Å; A305-L322 HydrophobicContact CB-CD1 4.38Å; I317-L322 HydrophobicContact CG2-CB 4.27Å; P318-L322 PolarHBondContact O-N 2.95Å; E319-L322 PolarHBondContact O-N 2.81Å; L322-A324 PolarHBondContact O-N 3.29Å; L322-A325 WeakPolarHBondContact O-CB 3.32Å; L322-A325 PolarHBondContact O-N 3.49Å; L322-V326 WeakPolarHBondContact O-CG2 3.37Å; L322-V326 PolarHBondContact O-N 2.96Å
323	T	88.1	Confident	85.6	Confident	30 Å²	30	53.7 Å²	53.7	18%	0.184	31%	0.306	C	S	.	.	H	α-helix	trans	-58	-49.1	175.4	-58.1	0	0	0	0	110	E319 A325 V326 W327	E319-T323 VanDerWaalsContact O-CB 3.31Å; E319-T323 WeakPolarHBondContact O-CB 3.43Å; E319-T323 PolarHBondContact O-N 3Å; E319-T323 PolarHBondContact O-OG1 3.02Å; T323-A325 VanDerWaalsContact C-N 3.31Å; T323-A325 PolarHBondContact O-N 3.24Å; T323-V326 PolarHBondContact O-N 2.8Å; T323-W327 HydrophobicContact CG2-CD2 4.1Å; T323-W327 HydrophobicContact CG2-CE3 3.67Å; T323-W327 HydrophobicContact CG2-CH2 3.9Å; T323-W327 HydrophobicContact CG2-CZ2 4.36Å; T323-W327 HydrophobicContact CG2-CZ3 3.54Å; T323-W327 PolarHBondContact O-N 2.95Å
324	A	91.3	Very high	86.8	Confident	43 Å²	43	44.5 Å²	44.5	36%	0.355	28%	0.275	S	S	.	.	H	α-helix	trans	-60.1	-41.4	177.1	0	0	0	0	0	112.4	L320 H321 L322 W327 M328	L320-A324 VanDerWaalsContact O-CB 3.22Å; L320-A324 WeakPolarHBondContact O-CB 3.29Å; L320-A324 PolarHBondContact O-N 3.44Å; H321-A324 PolarHBondContact O-N 3.45Å; L322-A324 PolarHBondContact O-N 3.29Å; A324-W327 PolarHBondContact O-N 3.33Å; A324-M328 HydrophobicContact CB-CE 4.3Å; A324-M328 WeakPolarHBondContact O-CB 3.23Å; A324-M328 WeakPolarHBondContact O-CE 3.08Å; A324-M328 WeakPolarHBondContact O-CG 3.47Å; A324-M328 PolarHBondContact O-N 2.84Å
325	A	93.1	Very high	88.1	Confident	0 Å²	0	41.5 Å²	41.5	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-63	-43.9	179.2	0	0	0	0	0	113.1	P301 H321 L322 T323 M328 S329	P301-A325 HydrophobicContact CB-CB 3.94Å; H321-A325 VanDerWaalsContact O-CB 3.22Å; H321-A325 WeakPolarHBondContact O-CB 3.47Å; H321-A325 PolarHBondContact O-N 3.49Å; L322-A325 WeakPolarHBondContact O-CB 3.32Å; L322-A325 PolarHBondContact O-N 3.49Å; T323-A325 VanDerWaalsContact C-N 3.31Å; T323-A325 PolarHBondContact O-N 3.24Å; A325-M328 PolarHBondContact O-N 3.25Å; A325-S329 PolarHBondContact O-N 3.02Å; A325-S329 VanDerWaalsContact O-N 3.16Å
326	V	91.5	Very high	89.3	Confident	1 Å²	1	39.8 Å²	39.8	1%	0.006	23%	0.229	C	C	.	.	H	α-helix	trans	-65.7	-41.3	175.6	171.6	0	0	0	0	110.8	E171 Y302 L322 T323 M328 S329 F330	E171-V326 HydrophobicContact CB-CG2 4.23Å; E171-V326 HydrophobicContact CG-CG2 4.05Å; Y302-V326 HydrophobicContact CD2-CG2 4.01Å; Y302-V326 HydrophobicContact CE2-CG2 3.86Å; L322-V326 WeakPolarHBondContact O-CG2 3.37Å; L322-V326 PolarHBondContact O-N 2.96Å; T323-V326 PolarHBondContact O-N 2.8Å; V326-M328 VanDerWaalsContact C-N 3.35Å; V326-M328 PolarHBondContact O-N 3.46Å; V326-S329 PolarHBondContact O-N 3.18Å; V326-S329 PolarHBondContact O-OG 3.35Å; V326-F330 HydrophobicContact CG1-CD2 4.02Å; V326-F330 HydrophobicContact CG1-CE2 3.38Å; V326-F330 HydrophobicContact CG1-CZ 3.69Å; V326-F330 WeakPolarHBondContact O-CD2 3.28Å; V326-F330 WeakPolarHBondContact O-CG 3.34Å; V326-F330 PolarHBondContact O-N 3.03Å; V326-F330 VanDerWaalsContact O-N 3.09Å
327	W	93.5	Very high	90.4	Very high	37 Å²	37	34 Å²	34	14%	0.14	19%	0.192	C	C	.	.	H	α-helix	trans	-67.4	-36.7	179.2	-90.8	-115.9	0	0	0	112.2	K25 S28 E172 T323 A324 F330 A331	K25-W327 HydrophobicContact CB-CH2 4.36Å; K25-W327 HydrophobicContact CB-CZ2 3.68Å; K25-W327 HydrophobicContact CD-CH2 3.8Å; K25-W327 HydrophobicContact CD-CZ2 3.91Å; K25-W327 HydrophobicContact CG-CH2 3.9Å; K25-W327 HydrophobicContact CG-CZ2 3.47Å; K25-W327 VanDerWaalsContact CG-CZ2 3.47Å; S28-W327 PolarHBondContact OG-NE1 3.48Å; E172-W327 WeakPolarHBondContact OE2-CH2 3.16Å; T323-W327 HydrophobicContact CG2-CD2 4.1Å; T323-W327 HydrophobicContact CG2-CE3 3.67Å; T323-W327 HydrophobicContact CG2-CH2 3.9Å; T323-W327 HydrophobicContact CG2-CZ2 4.36Å; T323-W327 HydrophobicContact CG2-CZ3 3.54Å; T323-W327 PolarHBondContact O-N 2.95Å; A324-W327 PolarHBondContact O-N 3.33Å; W327-F330 PolarHBondContact O-N 3.36Å; W327-A331 WeakPolarHBondContact O-CB 3.37Å; W327-A331 PolarHBondContact O-N 2.96Å
328	M	94.5	Very high	91.1	Very high	63 Å²	63	37.7 Å²	37.7	31%	0.31	21%	0.211	S	C	.	.	H	α-helix	trans	-63.7	-40.5	173.9	-75.1	-175.1	-76.1	0	0	111.9	L298 P301 A324 A325 V326 F330 A331 Q332	L298-M328 HydrophobicContact CD2-CB 4.08Å; L298-M328 HydrophobicContact CD2-CG 4.27Å; L298-M328 CarbonylContact O-C 3.06Å; L298-M328 WeakPolarHBondContact O-CB 3.17Å; P301-M328 HydrophobicContact CB-CE 3.45Å; P301-M328 VanDerWaalsContact CB-CE 3.45Å; P301-M328 HydrophobicContact CG-CE 3.39Å; P301-M328 HydrophobicContact CG-SD 3.97Å; A324-M328 HydrophobicContact CB-CE 4.3Å; A324-M328 WeakPolarHBondContact O-CB 3.23Å; A324-M328 WeakPolarHBondContact O-CE 3.08Å; A324-M328 WeakPolarHBondContact O-CG 3.47Å; A324-M328 PolarHBondContact O-N 2.84Å; A325-M328 PolarHBondContact O-N 3.25Å; V326-M328 VanDerWaalsContact C-N 3.35Å; V326-M328 PolarHBondContact O-N 3.46Å; M328-F330 VanDerWaalsContact C-N 3.33Å; M328-F330 PolarHBondContact O-N 2.68Å; M328-A331 PolarHBondContact O-N 3.04Å; M328-Q332 PolarHBondContact O-N 3.23Å
329	S	93.5	Very high	91.5	Very high	5 Å²	5	34.6 Å²	34.6	4%	0.035	19%	0.189	C	C	.	.	H	α-helix	trans	-65.9	-35.1	176.8	78.3	0	0	0	0	112.2	A325 V326 Q332	A325-S329 PolarHBondContact O-N 3.02Å; A325-S329 VanDerWaalsContact O-N 3.16Å; V326-S329 PolarHBondContact O-N 3.18Å; V326-S329 PolarHBondContact O-OG 3.35Å; S329-Q332 WeakPolarHBondContact O-CB 3.39Å
330	F	93.6	Very high	91.8	Very high	13 Å²	13	29 Å²	29	6%	0.057	16%	0.163	C	C	.	.	H	α-helix	trans	-68.7	-42.5	171.7	-63.4	-32.1	0	0	0	112.8	L29 I32 F76 V79 Q173 V326 W327 M328 Q332 A333	L29-F330 HydrophobicContact CD1-CB 4.45Å; L29-F330 HydrophobicContact CD1-CD2 3.83Å; L29-F330 HydrophobicContact CD1-CE2 4.35Å; L29-F330 HydrophobicContact CD1-CG 4.29Å; I32-F330 HydrophobicContact CG2-CB 4.33Å; F76-F330 HydrophobicContact CD1-CD1 4.25Å; F76-F330 HydrophobicContact CE1-CB 4.25Å; F76-F330 AromaticContact CE1-CD1 3.54Å; F76-F330 HydrophobicContact CE1-CD1 3.54Å; F76-F330 HydrophobicContact CE1-CE1 4.14Å; F76-F330 HydrophobicContact CE1-CG 4.07Å; F76-F330 HydrophobicContact CZ-CB 4.04Å; F76-F330 HydrophobicContact CZ-CD1 4.16Å; F76-F330 HydrophobicContact CZ-CG 4.37Å; V79-F330 HydrophobicContact CG1-CE2 4.12Å; V79-F330 HydrophobicContact CG1-CZ 4.18Å; V79-F330 HydrophobicContact CG2-CZ 4.19Å; Q173-F330 VanDerWaalsContact OE1-CZ 3.32Å; V326-F330 HydrophobicContact CG1-CD2 4.02Å; V326-F330 HydrophobicContact CG1-CE2 3.38Å; V326-F330 HydrophobicContact CG1-CZ 3.69Å; V326-F330 WeakPolarHBondContact O-CD2 3.28Å; V326-F330 WeakPolarHBondContact O-CG 3.34Å; V326-F330 PolarHBondContact O-N 3.03Å; V326-F330 VanDerWaalsContact O-N 3.09Å; W327-F330 PolarHBondContact O-N 3.36Å; M328-F330 VanDerWaalsContact C-N 3.33Å; M328-F330 PolarHBondContact O-N 2.68Å; F330-Q332 PolarHBondContact O-N 2.9Å; F330-Q332 VanDerWaalsContact O-N 3.12Å; F330-A333 VanDerWaalsContact O-CB 3.26Å; F330-A333 WeakPolarHBondContact O-CB 3.25Å; F330-A333 PolarHBondContact O-N 3.17Å
331	A	94.3	Very high	92	Very high	35 Å²	35	24 Å²	24	29%	0.289	14%	0.135	S	C	.	.	H	α-helix	trans	-58.9	-25.5	179.1	0	0	0	0	0	113.2	I32 W327 M328 A333 G334	I32-A331 HydrophobicContact CD1-CB 4.48Å; W327-A331 WeakPolarHBondContact O-CB 3.37Å; W327-A331 PolarHBondContact O-N 2.96Å; M328-A331 PolarHBondContact O-N 3.04Å; A331-A333 PolarHBondContact O-N 3.16Å; A331-A333 VanDerWaalsContact O-N 3.11Å; A331-G334 PolarHBondContact O-N 3.37Å
332	Q	94.7	Very high	92	Very high	3 Å²	3	25.8 Å²	25.8	1%	0.014	15%	0.146	C	C	.	.	H	α-helix	trans	-52.7	-32	172.8	177.5	60.7	27.5	0	0	112.7	A294 F295 L298 M328 S329 F330 G334 A335	A294-Q332 PolarHBondContact O-OE1 3Å; F295-Q332 HydrophobicContact CD2-CG 4.14Å; L298-Q332 HydrophobicContact CB-CB 4.29Å; L298-Q332 HydrophobicContact CD1-CB 4.18Å; L298-Q332 VanDerWaalsContact CD1-OE1 3.24Å; M328-Q332 PolarHBondContact O-N 3.23Å; S329-Q332 WeakPolarHBondContact O-CB 3.39Å; F330-Q332 PolarHBondContact O-N 2.9Å; F330-Q332 VanDerWaalsContact O-N 3.12Å; Q332-G334 PolarHBondContact O-N 3.41Å; Q332-A335 WeakPolarHBondContact O-CB 3.29Å; Q332-A335 PolarHBondContact O-N 3.26Å; Q332-A335 VanDerWaalsContact O-N 3.12Å
333	A	93.3	Very high	91.8	Very high	0 Å²	0	29 Å²	29	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-56	-39.1	178.5	0	0	0	0	0	112.7	S36 N40 F76 F330 A331	S36-A333 WeakPolarHBondContact OG-CB 3.35Å; S36-A333 PolarHBondContact OG-O 3.25Å; N40-A333 PolarHBondContact ND2-O 3.34Å; F76-A333 HydrophobicContact CE2-CB 4.04Å; F76-A333 HydrophobicContact CZ-CB 3.92Å; F330-A333 VanDerWaalsContact O-CB 3.26Å; F330-A333 WeakPolarHBondContact O-CB 3.25Å; F330-A333 PolarHBondContact O-N 3.17Å; A331-A333 PolarHBondContact O-N 3.16Å; A331-A333 VanDerWaalsContact O-N 3.11Å
334	G	92.2	Very high	91.6	Very high	13 Å²	13	27.7 Å²	27.7	13%	0.134	15%	0.151	C	C	.	.	H	α-helix	trans	-86	-8.8	-178.6	0	0	0	0	0	114.3	A331 Q332 I338	A331-G334 PolarHBondContact O-N 3.37Å; Q332-G334 PolarHBondContact O-N 3.41Å; G334-I338 VanDerWaalsContact O-CD1 3.26Å; G334-I338 WeakPolarHBondContact O-CD1 3.28Å; G334-I338 WeakPolarHBondContact O-CG1 3.4Å
335	A	92.9	Very high	91	Very high	13 Å²	13	31.9 Å²	31.9	11%	0.107	16%	0.162	C	C	.	.	H	α-helix	trans	-72	-34.6	-173.1	0	0	0	0	0	112.8	L298 Q332 I338 I339	L298-A335 HydrophobicContact CD1-CB 4.3Å; Q332-A335 WeakPolarHBondContact O-CB 3.29Å; Q332-A335 PolarHBondContact O-N 3.26Å; Q332-A335 VanDerWaalsContact O-N 3.12Å; A335-I338 PolarHBondContact O-N 2.82Å; A335-I339 HydrophobicContact CB-CD1 4.26Å; A335-I339 VanDerWaalsContact O-CG1 3.29Å; A335-I339 WeakPolarHBondContact O-CG1 2.99Å; A335-I339 PolarHBondContact O-N 2.96Å
336	N	92.1	Very high	90.4	Very high	1 Å²	1	34.9 Å²	34.9	1%	0.005	18%	0.176	C	C	.	.	H	α-helix	trans	-61.5	-49.6	-170.9	-64.2	-25.6	0	0	0	113.5	L64 D68 I291 S340	L64-N336 HydrophobicContact CD2-CB 4.36Å; L64-N336 WeakPolarHBondContact CD2-ND2 3.48Å; L64-N336 WeakPolarHBondContact CG-ND2 3.41Å; D68-N336 PolarHBondContact OD2-ND2 3.43Å; I291-N336 VanDerWaalsContact CG2-OD1 3.31Å; I291-N336 WeakPolarHBondContact CG2-OD1 3.49Å; N336-S340 VanDerWaalsContact O-CB 3.27Å; N336-S340 WeakPolarHBondContact O-CB 3.4Å; N336-S340 PolarHBondContact O-N 2.88Å; N336-S340 PolarHBondContact O-OG 3.28Å
337	P	92.8	Very high	90	Very high	4 Å²	4	34.9 Å²	34.9	3%	0.026	18%	0.175	C	C	.	.	H	α-helix	trans	-66.3	-40.4	176.8	-19.9	33.8	0	0	0	112.5	G39 N40 L43 I339 S340 F341	G39-P337 WeakPolarHBondContact O-CG 3.29Å; N40-P337 HydrophobicContact CB-CG 4.25Å; N40-P337 WeakPolarHBondContact OD1-CD 3.18Å; N40-P337 VanDerWaalsContact OD1-CG 3.23Å; N40-P337 WeakPolarHBondContact OD1-CG 3.37Å; L43-P337 HydrophobicContact CB-CB 4.48Å; L43-P337 HydrophobicContact CD2-CB 4.22Å; L43-P337 HydrophobicContact CD2-CG 4.46Å; P337-I339 PolarHBondContact O-N 3.45Å; P337-S340 PolarHBondContact O-N 3.15Å; P337-F341 HydrophobicContact CB-CD2 4.23Å; P337-F341 HydrophobicContact CB-CE2 3.98Å; P337-F341 WeakPolarHBondContact O-CB 3.31Å; P337-F341 WeakPolarHBondContact O-CD2 3.33Å; P337-F341 WeakPolarHBondContact O-CG 3.44Å; P337-F341 PolarHBondContact O-N 3.33Å
338	I	92.1	Very high	89.7	Confident	106 Å²	106	37.4 Å²	37.4	54%	0.544	19%	0.185	S	C	.	.	H	α-helix	trans	-58	-51.5	179.9	-63.4	172.2	0	0	0	109.8	G334 A335 S340 F341 M342	G334-I338 VanDerWaalsContact O-CD1 3.26Å; G334-I338 WeakPolarHBondContact O-CD1 3.28Å; G334-I338 WeakPolarHBondContact O-CG1 3.4Å; A335-I338 PolarHBondContact O-N 2.82Å; I338-S340 PolarHBondContact O-N 2.82Å; I338-F341 PolarHBondContact O-N 2.82Å; I338-M342 HydrophobicContact CG2-SD 4.12Å; I338-M342 WeakPolarHBondContact O-CB 3.05Å; I338-M342 VanDerWaalsContact O-CG 3.26Å; I338-M342 WeakPolarHBondContact O-CG 3.16Å; I338-M342 PolarHBondContact O-N 2.87Å
339	I	93.3	Very high	89.1	Confident	20 Å²	20	39.2 Å²	39.2	10%	0.103	20%	0.195	C	C	.	.	H	α-helix	trans	-64.8	-42.7	179.9	-63.6	166.7	0	0	0	110.4	L290 I291 A294 A335 P337 F341 M342 F343	L290-I339 HydrophobicContact CB-CG2 3.78Å; I291-I339 HydrophobicContact CG1-CB 4.04Å; I291-I339 HydrophobicContact CG1-CD1 4.25Å; I291-I339 HydrophobicContact CG1-CG2 3.7Å; A294-I339 HydrophobicContact CB-CD1 3.55Å; A335-I339 HydrophobicContact CB-CD1 4.26Å; A335-I339 VanDerWaalsContact O-CG1 3.29Å; A335-I339 WeakPolarHBondContact O-CG1 2.99Å; A335-I339 PolarHBondContact O-N 2.96Å; P337-I339 PolarHBondContact O-N 3.45Å; I339-F341 PolarHBondContact O-N 2.99Å; I339-M342 PolarHBondContact O-N 3.37Å; I339-F343 HydrophobicContact CG2-CD2 4.06Å; I339-F343 WeakPolarHBondContact O-CD2 3.28Å; I339-F343 PolarHBondContact O-N 2.96Å
340	S	90.7	Very high	88.7	Confident	0 Å²	0	43.6 Å²	43.6	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-60.7	-46.4	-179.9	-62.1	0	0	0	0	112	N336 P337 I338 N344	N336-S340 VanDerWaalsContact O-CB 3.27Å; N336-S340 WeakPolarHBondContact O-CB 3.4Å; N336-S340 PolarHBondContact O-N 2.88Å; N336-S340 PolarHBondContact O-OG 3.28Å; P337-S340 PolarHBondContact O-N 3.15Å; I338-S340 PolarHBondContact O-N 2.82Å; S340-N344 WeakPolarHBondContact O-CB 3.13Å; S340-N344 PolarHBondContact O-N 2.94Å
341	F	89.3	Confident	88.2	Confident	35 Å²	35	44.7 Å²	44.7	15%	0.154	22%	0.217	C	C	.	.	H	α-helix	trans	-71	-35.3	178.1	-67.5	-52.7	0	0	0	112.9	L43 L46 P337 I338 I339 L347 R348 L351	L43-F341 HydrophobicContact CB-CE2 4.42Å; L43-F341 HydrophobicContact CB-CZ 4.09Å; L43-F341 HydrophobicContact CD1-CE1 4.17Å; L43-F341 HydrophobicContact CD1-CZ 4.03Å; L46-F341 HydrophobicContact CD2-CE1 4.17Å; P337-F341 HydrophobicContact CB-CD2 4.23Å; P337-F341 HydrophobicContact CB-CE2 3.98Å; P337-F341 WeakPolarHBondContact O-CB 3.31Å; P337-F341 WeakPolarHBondContact O-CD2 3.33Å; P337-F341 WeakPolarHBondContact O-CG 3.44Å; P337-F341 PolarHBondContact O-N 3.33Å; I338-F341 PolarHBondContact O-N 2.82Å; I339-F341 PolarHBondContact O-N 2.99Å; F341-L347 HydrophobicContact CD1-CB 4.13Å; F341-L347 HydrophobicContact CE1-CB 4.29Å; F341-R348 HydrophobicContact CB-CG 4.31Å; F341-R348 WeakPolarHBondContact O-CD 3.32Å; F341-R348 WeakPolarHBondContact O-CG 3.29Å; F341-R348 PolarHBondContact O-NE 2.9Å; F341-L351 HydrophobicContact CD1-CD2 4.12Å; F341-L351 HydrophobicContact CE1-CB 4.33Å; F341-L351 HydrophobicContact CE1-CD1 4.25Å; F341-L351 HydrophobicContact CE1-CD2 3.7Å; F341-L351 HydrophobicContact CE1-CG 4.31Å; F341-L351 HydrophobicContact CE2-CD2 4.47Å; F341-L351 HydrophobicContact CZ-CD1 4.18Å; F341-L351 HydrophobicContact CZ-CD2 3.89Å
342	M	87.8	Confident	87.7	Confident	116 Å²	116	51.3 Å²	51.3	57%	0.571	23%	0.234	S	C	*	.	H	α-helix	trans	-63.3	-47.6	176.9	-76.3	-174.8	73.3	0	0	112	I338 I339 R348	I338-M342 HydrophobicContact CG2-SD 4.12Å; I338-M342 WeakPolarHBondContact O-CB 3.05Å; I338-M342 VanDerWaalsContact O-CG 3.26Å; I338-M342 WeakPolarHBondContact O-CG 3.16Å; I338-M342 PolarHBondContact O-N 2.87Å; I339-M342 PolarHBondContact O-N 3.37Å; M342-R348 PolarHBondContact O-NH2 3.44Å
343	F	83.8	Confident	87.1	Confident	70 Å²	70	54 Å²	54	31%	0.307	26%	0.257	S	S	.	.	H	α-helix	trans	-97.1	-14.8	-168.9	-70.2	-83.4	0	0	0	114.6	M287 L290 I339	M287-F343 HydrophobicContact CB-CB 4.26Å; M287-F343 HydrophobicContact CG-CB 4.37Å; L290-F343 HydrophobicContact CD1-CD1 3.61Å; L290-F343 HydrophobicContact CD1-CD2 3.53Å; L290-F343 HydrophobicContact CD1-CE1 3.47Å; L290-F343 VanDerWaalsContact CD1-CE1 3.47Å; L290-F343 HydrophobicContact CD1-CE2 3.4Å; L290-F343 VanDerWaalsContact CD1-CE2 3.4Å; L290-F343 HydrophobicContact CD1-CG 3.64Å; L290-F343 HydrophobicContact CD1-CZ 3.36Å; I339-F343 HydrophobicContact CG2-CD2 4.06Å; I339-F343 WeakPolarHBondContact O-CD2 3.28Å; I339-F343 PolarHBondContact O-N 2.96Å
344	N	83.1	Confident	86.3	Confident	4 Å²	4	55.7 Å²	55.7	2%	0.021	27%	0.268	C	S	.	.			trans	-109	99.4	175.5	-158.8	-20.8	0	0	0	111.8	Y58 M287 S340 E346 L347 R348	Y58-N344 PolarHBondContact OH-ND2 3.03Å; M287-N344 HydrophobicContact SD-CB 3.93Å; S340-N344 WeakPolarHBondContact O-CB 3.13Å; S340-N344 PolarHBondContact O-N 2.94Å; N344-E346 PolarHBondContact O-N 3.1Å; N344-E346 WeakPolarHBondContact OD1-CB 3.35Å; N344-E346 PolarHBondContact OD1-N 2.91Å; N344-E346 VanDerWaalsContact OD1-N 3.16Å; N344-L347 HydrophobicContact CB-CB 4.15Å; N344-L347 HydrophobicContact CB-CD1 3.77Å; N344-L347 HydrophobicContact CB-CG 3.86Å; N344-L347 PolarHBondContact O-N 3.12Å; N344-R348 PolarHBondContact O-N 3.38Å
345	K	79.8	Confident	85.4	Confident	131 Å²	131	60.4 Å²	60.4	57%	0.57	29%	0.285	S	S	*	.	H	α-helix	trans	-61.3	-32.9	175.8	-70.7	-174.1	177.9	-172.5	0	112.6	R348 I349	K345-R348 PolarHBondContact O-N 2.79Å; K345-I349 WeakPolarHBondContact O-CG1 3Å; K345-I349 PolarHBondContact O-N 2.93Å
346	E	80.6	Confident	84.2	Confident	63 Å²	63	63.7 Å²	63.7	29%	0.294	31%	0.308	S	S	.	.	H	α-helix	trans	-63.4	-48.3	179.6	-171.7	61.9	-159.1	0	0	110.1	L53 N344 R348 I349 R350	L53-E346 HydrophobicContact CD2-CG 4.25Å; N344-E346 PolarHBondContact O-N 3.1Å; N344-E346 WeakPolarHBondContact OD1-CB 3.35Å; N344-E346 PolarHBondContact OD1-N 2.91Å; N344-E346 VanDerWaalsContact OD1-N 3.16Å; E346-R348 VanDerWaalsContact C-N 3.26Å; E346-R348 PolarHBondContact O-N 2.03Å; E346-I349 PolarHBondContact O-N 3.41Å; E346-I349 VanDerWaalsContact O-N 3.11Å; E346-R350 HydrophobicContact CG-CG 4.4Å; E346-R350 WeakPolarHBondContact O-CG 3.5Å; E346-R350 PolarHBondContact O-N 2.94Å; E346-R350 IonicContact OE1-CZ 3.34Å; E346-R350 IonicContact OE1-NE 2.76Å; E346-R350 PolarHBondContact OE1-NE 3.47Å; E346-R350 IonicContact OE1-NH2 3.01Å; E346-R350 PolarHBondContact OE1-NH2 2.9Å
347	L	83.3	Confident	82.5	Confident	0 Å²	0	68.1 Å²	68.1	0%	0	34%	0.337	C	S	.	.	H	α-helix	trans	-56.7	-40.4	176.8	-66.1	-179.5	0	0	0	111.9	L43 L46 L47 L53 Y58 L61 F341 N344 R350 L351	L43-L347 HydrophobicContact CD1-CD1 4.12Å; L46-L347 HydrophobicContact CD2-CB 4.35Å; L46-L347 HydrophobicContact CD2-CD2 4.07Å; L47-L347 HydrophobicContact CD2-CD2 4.05Å; L53-L347 HydrophobicContact CD1-CD2 3.6Å; L53-L347 HydrophobicContact CD2-CD2 4.25Å; Y58-L347 HydrophobicContact CE1-CD2 4.19Å; L61-L347 HydrophobicContact CD2-CD1 4.42Å; F341-L347 HydrophobicContact CD1-CB 4.13Å; F341-L347 HydrophobicContact CE1-CB 4.29Å; N344-L347 HydrophobicContact CB-CB 4.15Å; N344-L347 HydrophobicContact CB-CD1 3.77Å; N344-L347 HydrophobicContact CB-CG 3.86Å; N344-L347 PolarHBondContact O-N 3.12Å; L347-R350 PolarHBondContact O-N 2.99Å; L347-L351 WeakPolarHBondContact O-CB 3.44Å; L347-L351 PolarHBondContact O-N 3.45Å
348	R	85.4	Confident	80.8	Confident	90 Å²	90	72.4 Å²	72.4	34%	0.34	37%	0.366	S	S	.	.	H	α-helix	trans	-65.4	-41.5	177.2	-74.7	-172.1	-80.3	170.8	-14.9	113.3	F341 M342 N344 K345 E346 R352	F341-R348 HydrophobicContact CB-CG 4.31Å; F341-R348 WeakPolarHBondContact O-CD 3.32Å; F341-R348 WeakPolarHBondContact O-CG 3.29Å; F341-R348 PolarHBondContact O-NE 2.9Å; M342-R348 PolarHBondContact O-NH2 3.44Å; N344-R348 PolarHBondContact O-N 3.38Å; K345-R348 PolarHBondContact O-N 2.79Å; E346-R348 VanDerWaalsContact C-N 3.26Å; E346-R348 PolarHBondContact O-N 2.03Å; R348-R352 WeakPolarHBondContact O-CG 3.41Å; R348-R352 PolarHBondContact O-N 3.48Å; R348-R352 VanDerWaalsContact O-N 3.09Å
349	I	83.6	Confident	79.1	Confident	102 Å²	102	74.5 Å²	74.5	52%	0.523	38%	0.378	S	S	.	.	H	α-helix	trans	-64.6	-47	178.8	-68.6	166.2	0	0	0	109.4	K345 E346 R352 A353	K345-I349 WeakPolarHBondContact O-CG1 3Å; K345-I349 PolarHBondContact O-N 2.93Å; E346-I349 PolarHBondContact O-N 3.41Å; E346-I349 VanDerWaalsContact O-N 3.11Å; I349-R352 PolarHBondContact O-N 3.21Å; I349-A353 PolarHBondContact O-N 3.48Å
350	R	83.9	Confident	76.9	Confident	97 Å²	97	75.4 Å²	75.4	37%	0.366	39%	0.393	S	S	.	.	H	α-helix	trans	-66.8	-38.6	179.4	-59.6	-57	178.9	158.8	-1	112.9	L46 D50 E346 L347 A353 C354	L46-R350 HydrophobicContact CD1-CB 3.86Å; D50-R350 WeakPolarHBondContact OD2-CD 3.36Å; D50-R350 WeakPolarHBondContact OD2-CG 3.34Å; D50-R350 IonicContact OD2-NE 3.63Å; E346-R350 HydrophobicContact CG-CG 4.4Å; E346-R350 WeakPolarHBondContact O-CG 3.5Å; E346-R350 PolarHBondContact O-N 2.94Å; E346-R350 IonicContact OE1-CZ 3.34Å; E346-R350 IonicContact OE1-NE 2.76Å; E346-R350 PolarHBondContact OE1-NE 3.47Å; E346-R350 IonicContact OE1-NH2 3.01Å; E346-R350 PolarHBondContact OE1-NH2 2.9Å; L347-R350 PolarHBondContact O-N 2.99Å; R350-A353 PolarHBondContact O-N 2.99Å; R350-C354 PolarHBondContact O-N 3.31Å
351	L	83.9	Confident	74.5	Confident	35 Å²	35	81.9 Å²	81.9	18%	0.183	43%	0.432	C	S	.	.	H	α-helix	trans	-59.2	-48.2	173.9	-171.6	71.9	0	0	0	111.1	L46 F341 L347 A353 C354 F355	L46-L351 HydrophobicContact CD2-CB 4.11Å; L46-L351 HydrophobicContact CD2-CD1 4.23Å; F341-L351 HydrophobicContact CD1-CD2 4.12Å; F341-L351 HydrophobicContact CE1-CB 4.33Å; F341-L351 HydrophobicContact CE1-CD1 4.25Å; F341-L351 HydrophobicContact CE1-CD2 3.7Å; F341-L351 HydrophobicContact CE1-CG 4.31Å; F341-L351 HydrophobicContact CE2-CD2 4.47Å; F341-L351 HydrophobicContact CZ-CD1 4.18Å; F341-L351 HydrophobicContact CZ-CD2 3.89Å; L347-L351 WeakPolarHBondContact O-CB 3.44Å; L347-L351 PolarHBondContact O-N 3.45Å; L351-A353 PolarHBondContact O-N 3.37Å; L351-C354 PolarHBondContact O-N 2.9Å; L351-F355 HydrophobicContact CD1-CD2 4.08Å; L351-F355 HydrophobicContact CD1-CE2 3.6Å; L351-F355 HydrophobicContact CD2-CE2 4.19Å; L351-F355 HydrophobicContact CG-CD2 3.83Å; L351-F355 HydrophobicContact CG-CE2 3.68Å; L351-F355 VanDerWaalsContact O-CD2 3.28Å; L351-F355 WeakPolarHBondContact O-CD2 3.37Å; L351-F355 PolarHBondContact O-N 3.49Å
352	R	84.1	Confident	72.2	Confident	175 Å²	175	89.3 Å²	89.3	66%	0.66	47%	0.467	S	S	*	.	H	α-helix	trans	-60.9	-43.8	176.9	-71.7	177.6	-166.9	-164.4	0.4	111.8	R348 I349 C354 F355 S356	R348-R352 WeakPolarHBondContact O-CG 3.41Å; R348-R352 PolarHBondContact O-N 3.48Å; R348-R352 VanDerWaalsContact O-N 3.09Å; I349-R352 PolarHBondContact O-N 3.21Å; R352-C354 VanDerWaalsContact C-N 3.3Å; R352-C354 PolarHBondContact O-N 3.02Å; R352-F355 PolarHBondContact O-N 3.47Å; R352-S356 WeakPolarHBondContact O-CB 3.29Å; R352-S356 PolarHBondContact O-N 2.86Å; R352-S356 PolarHBondContact O-OG 3.24Å; R352-S356 VanDerWaalsContact O-OG 3.13Å
353	A	81.9	Confident	69.7	Low	58 Å²	58	89.7 Å²	89.7	48%	0.479	48%	0.476	S	S	.	.	H	α-helix	trans	-60.4	-40.4	176.4	0	0	0	0	0	112	I349 R350 L351 C357	I349-A353 PolarHBondContact O-N 3.48Å; R350-A353 PolarHBondContact O-N 2.99Å; L351-A353 PolarHBondContact O-N 3.37Å; A353-C357 WeakPolarHBondContact O-CB 3.48Å; A353-C357 PolarHBondContact O-N 3.39Å
354	C	75.6	Confident	67.5	Low	36 Å²	36	92.2 Å²	92.2	24%	0.243	50%	0.5	C	S	.	.	H	α-helix	trans	-66	-43.4	176.3	-166.7	0	0	0	0	112	R350 L351 R352 C357 C358	R350-C354 PolarHBondContact O-N 3.31Å; L351-C354 PolarHBondContact O-N 2.9Å; R352-C354 VanDerWaalsContact C-N 3.3Å; R352-C354 PolarHBondContact O-N 3.02Å; C354-C357 PolarHBondContact O-N 3.18Å; C354-C358 PolarHBondContact O-N 3.34Å; C354-C358 VanDerWaalsContact O-N 3.09Å; C354-C358 PolarHBondContact O-SG 3.45Å
355	F	74.1	Confident	65.5	Low	112 Å²	112	100.9 Å²	100.9	49%	0.491	54%	0.542	S	S	.	.	H	α-helix	trans	-67	-40.9	176	-82.3	-71.4	0	0	0	112.5	L351 R352 C357 C358 L359	L351-F355 HydrophobicContact CD1-CD2 4.08Å; L351-F355 HydrophobicContact CD1-CE2 3.6Å; L351-F355 HydrophobicContact CD2-CE2 4.19Å; L351-F355 HydrophobicContact CG-CD2 3.83Å; L351-F355 HydrophobicContact CG-CE2 3.68Å; L351-F355 VanDerWaalsContact O-CD2 3.28Å; L351-F355 WeakPolarHBondContact O-CD2 3.37Å; L351-F355 PolarHBondContact O-N 3.49Å; R352-F355 PolarHBondContact O-N 3.47Å; F355-C357 VanDerWaalsContact C-N 3.28Å; F355-C357 PolarHBondContact O-N 3.09Å; F355-C358 PolarHBondContact O-N 3.48Å; F355-C358 VanDerWaalsContact O-N 3.09Å; F355-L359 HydrophobicContact CB-CD1 4.49Å; F355-L359 HydrophobicContact CD1-CD1 4.43Å; F355-L359 VanDerWaalsContact O-CD1 3.28Å; F355-L359 WeakPolarHBondContact O-CD1 3.2Å; F355-L359 PolarHBondContact O-N 3.5Å
356	S	66.4	Low	63.3	Low	83 Å²	83	103.3 Å²	103.3	58%	0.58	56%	0.556	S	S	*	*	H	α-helix	trans	-63	-33.7	174.8	-65.9	0	0	0	0	112.5	R352 C358 G360	R352-S356 WeakPolarHBondContact O-CB 3.29Å; R352-S356 PolarHBondContact O-N 2.86Å; R352-S356 PolarHBondContact O-OG 3.24Å; R352-S356 VanDerWaalsContact O-OG 3.13Å; S356-C358 VanDerWaalsContact C-N 3.35Å; S356-G360 WeakPolarHBondContact O-CA 3.36Å; S356-G360 PolarHBondContact O-N 3.43Å
357	C	57.9	Low	61.6	Low	93 Å²	93	105.7 Å²	105.7	63%	0.628	58%	0.577	S	S	*	*	H	α-helix	trans	-73.5	-25.2	173.4	-170.1	0	0	0	0	113.1	A353 C354 F355	A353-C357 WeakPolarHBondContact O-CB 3.48Å; A353-C357 PolarHBondContact O-N 3.39Å; C354-C357 PolarHBondContact O-N 3.18Å; F355-C357 VanDerWaalsContact C-N 3.28Å; F355-C357 PolarHBondContact O-N 3.09Å
358	C	57.3	Low	59.5	Low	94 Å²	94	116.7 Å²	116.7	64%	0.635	62%	0.62	S	S	*	*	H	α-helix	trans	-85.6	-23.4	175.4	-65.4	0	0	0	0	113.2	C354 F355 S356	C354-C358 PolarHBondContact O-N 3.34Å; C354-C358 VanDerWaalsContact O-N 3.09Å; C354-C358 PolarHBondContact O-SG 3.45Å; F355-C358 PolarHBondContact O-N 3.48Å; F355-C358 VanDerWaalsContact O-N 3.09Å; S356-C358 VanDerWaalsContact C-N 3.35Å
359	L	55.4	Low	57	Low	150 Å²	150	118 Å²	118	79%	0.785	64%	0.641	S	S	*	*	H	α-helix	trans	-102	-16	176.8	-82.7	108.6	0	0	0	114.2	F355	F355-L359 HydrophobicContact CB-CD1 4.49Å; F355-L359 HydrophobicContact CD1-CD1 4.43Å; F355-L359 VanDerWaalsContact O-CD1 3.28Å; F355-L359 WeakPolarHBondContact O-CD1 3.2Å; F355-L359 PolarHBondContact O-N 3.5Å
360	G	46.6	Very low	54.9	Low	40 Å²	40	120.9 Å²	120.9	41%	0.412	66%	0.656	S	S	.	*	S	Bend	trans	-100.9	121.8	179.7	0	0	0	0	0	111.7	S356 Q362	S356-G360 WeakPolarHBondContact O-CA 3.36Å; S356-G360 PolarHBondContact O-N 3.43Å; G360-Q362 PolarHBondContact O-N 2.88Å
361	T	41.3	Very low	52.9	Low	135 Å²	135	126.8 Å²	126.8	83%	0.828	69%	0.693	S	S	*	*			trans	-45.5	129.7	159.5	32.2	0	0	0	0	109.7	T363	T361-T363 PolarHBondContact O-N 3.05Å
362	Q	39.5	Very low	51.3	Low	192 Å²	192	131.4 Å²	131.4	90%	0.897	72%	0.718	S	S	*	*			trans	-49.5	111.9	175	-73.2	177.6	4.1	0	0	109.9	G360	G360-Q362 PolarHBondContact O-N 2.88Å
363	T	36.5	Very low	49.6	Very low	124 Å²	124	129.1 Å²	129.1	76%	0.761	72%	0.721	S	S	*	*	P	Polyproline II helix	trans	-93.2	128.5	149	51.7	0	0	0	0	107.1	T361 M365	T361-T363 PolarHBondContact O-N 3.05Å; T363-M365 PolarHBondContact O-N 2.63Å
364	P	37.9	Very low	47.8	Very low	123 Å²	123	133 Å²	133	80%	0.799	74%	0.735	S	S	*	*	P	Polyproline II helix	trans	-61.3	138	-173	24.1	-32	0	0	0	111.1	E366	P364-E366 PolarHBondContact O-N 2.86Å
365	M	39.6	Very low	46.2	Very low	185 Å²	185	138.7 Å²	138.7	91%	0.911	76%	0.764	S	S	*	*	P	Polyproline II helix	trans	-61.7	118	175.5	-65.5	-90.2	-95.8	0	0	109.5	T363	T363-M365 PolarHBondContact O-N 2.63Å
366	E	34.4	Very low	44.4	Very low	183 Å²	183	140.4 Å²	140.4	86%	0.855	78%	0.781	S	S	*	*	P	Polyproline II helix	trans	-64.1	127	162.4	-103.4	-177.9	156.5	0	0	109	P364	P364-E366 PolarHBondContact O-N 2.86Å
367	P	44	Very low	42.9	Very low	113 Å²	113	144.2 Å²	144.2	73%	0.734	79%	0.794	S	S	*	*	P	Polyproline II helix	trans	-70.5	132.3	173.2	28.4	-30.5	0	0	0	109.4	C369	P367-C369 PolarHBondContact O-N 3.26Å
368	Y	40.8	Very low	41.9	Very low	230 Å²	230	147.9 Å²	147.9	90%	0.902	81%	0.806	S	S	*	*			trans	-53	109.6	168	-85.1	-100.6	0	0	0	110.1	I370	Y368-I370 PolarHBondContact O-N 3Å
369	C	32.6	Very low	40.7	Very low	117 Å²	117	152 Å²	152	79%	0.791	82%	0.819	S	S	*	*			trans	-71.9	115.7	161	-106.1	0	0	0	0	108.6	P367	P367-C369 PolarHBondContact O-N 3.26Å
370	I	39.3	Very low	39.5	Very low	163 Å²	163	152.2 Å²	152.2	84%	0.836	82%	0.822	S	S	*	*			trans	-82.2	117.9	158.3	-61.8	178.8	0	0	0	105.7	Y368	Y368-I370 PolarHBondContact O-N 3Å
371	I	41.2	Very low	38.8	Very low	221 Å²	221	162.4 Å²	162.4	100%	1.133	86%	0.859	S	S	*	*			trans	-108.7	0	161	-61.2	176.6	0	0	0	107.2

Retrieved 371 of 371 residues in 529.6 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).