A0A087YQT4_POEFO Loading...

P2Y purinoceptor 1

Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation.

AlphaFold DB (A0A3B3VY30), UniProt , Accession A0A087YQT4, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 349 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	42.5	Very low	43.3	Very low	218 Å²	218	115.4 Å²	115.4	100%	1.074	64%	0.635	S	S	*	*				0	0.8	0	-130.1	174.3	-146.8	0	0	113.6
2	T	40.4	Very low	42.8	Very low	120 Å²	120	114.5 Å²	114.5	74%	0.736	63%	0.629	S	S	*	*			trans	-100.2	-11.5	-176.1	31.1	0	0	0	0	114.5
3	T	43.6	Very low	42.4	Very low	116 Å²	116	114.4 Å²	114.4	71%	0.712	62%	0.621	S	S	*	*	H	α-helix	trans	-84.2	-28.1	179.4	24.6	0	0	0	0	114.1
4	A	44.1	Very low	42.2	Very low	69 Å²	69	110.6 Å²	110.6	57%	0.57	61%	0.607	S	S	*	*	H	α-helix	trans	-74.1	-32.3	179.3	0	0	0	0	0	113.3	Q7 T8	A4-Q7 PolarHBondContact O-N 3.32Å; A4-T8 PolarHBondContact O-N 3.39Å; A4-T8 PolarHBondContact O-OG1 3.06Å; A4-T8 VanDerWaalsContact O-OG1 3.11Å
5	L	45.6	Very low	42.4	Very low	124 Å²	124	112 Å²	112	65%	0.649	61%	0.612	S	S	*	*	H	α-helix	trans	-68.2	-33.5	179.3	-84.2	157.5	0	0	0	113	Q7 T8 S9	L5-Q7 VanDerWaalsContact C-N 3.35Å; L5-T8 WeakPolarHBondContact CA-OG1 3.47Å; L5-T8 PolarHBondContact O-OG1 2.9Å; L5-S9 PolarHBondContact O-N 3.36Å; L5-S9 PolarHBondContact O-OG 3.39Å
6	N	44.4	Very low	42.5	Very low	111 Å²	111	115.4 Å²	115.4	59%	0.594	62%	0.622	S	S	*	*	H	α-helix	trans	-73	-25.8	177.2	-88.2	-0.9	0	0	0	113.4	S9 F10	N6-S9 WeakPolarHBondContact CA-OG 3.32Å; N6-S9 PolarHBondContact O-OG 3.08Å; N6-F10 PolarHBondContact O-N 3.48Å; N6-F10 VanDerWaalsContact O-N 3.14Å
7	Q	43.4	Very low	43.1	Very low	139 Å²	139	117.5 Å²	117.5	65%	0.65	62%	0.619	S	S	*	*	H	α-helix	trans	-80.1	-35.8	179.6	-151.9	159.7	3.1	0	0	111	A4 L5 L11	A4-Q7 PolarHBondContact O-N 3.32Å; L5-Q7 VanDerWaalsContact C-N 3.35Å; Q7-L11 WeakPolarHBondContact O-CB 3.5Å; Q7-L11 WeakPolarHBondContact O-CD1 3.37Å; Q7-L11 WeakPolarHBondContact O-CG 3.32Å; Q7-L11 PolarHBondContact O-N 2.95Å
8	T	46.4	Very low	44.1	Very low	80 Å²	80	113.6 Å²	113.6	49%	0.491	61%	0.611	S	S	.	*	H	α-helix	trans	-67.2	-33.2	169.7	35.4	0	0	0	0	113.5	A4 L5 N12	A4-T8 PolarHBondContact O-N 3.39Å; A4-T8 PolarHBondContact O-OG1 3.06Å; A4-T8 VanDerWaalsContact O-OG1 3.11Å; L5-T8 WeakPolarHBondContact CA-OG1 3.47Å; L5-T8 PolarHBondContact O-OG1 2.9Å; T8-N12 WeakPolarHBondContact O-CB 3.42Å; T8-N12 PolarHBondContact O-N 3.06Å
9	S	41.9	Very low	45.7	Very low	55 Å²	55	108.5 Å²	108.5	39%	0.385	59%	0.586	S	S	.	*	H	α-helix	trans	-73.5	-38.6	175.1	63.2	0	0	0	0	112.5	L5 N6 N12 E13	L5-S9 PolarHBondContact O-N 3.36Å; L5-S9 PolarHBondContact O-OG 3.39Å; N6-S9 WeakPolarHBondContact CA-OG 3.32Å; N6-S9 PolarHBondContact O-OG 3.08Å; S9-N12 PolarHBondContact O-N 2.81Å; S9-E13 PolarHBondContact O-N 2.97Å
10	F	41.5	Very low	47	Very low	138 Å²	138	107.1 Å²	107.1	61%	0.605	58%	0.584	S	S	*	*	H	α-helix	trans	-67.2	-36.4	172.8	-108.1	-91.9	0	0	0	113.3	N6 S14	N6-F10 PolarHBondContact O-N 3.48Å; N6-F10 VanDerWaalsContact O-N 3.14Å; F10-S14 WeakPolarHBondContact O-CB 3.48Å; F10-S14 PolarHBondContact O-N 3.49Å; F10-S14 PolarHBondContact O-OG 3.08Å
11	L	42.6	Very low	48	Very low	99 Å²	99	104.8 Å²	104.8	52%	0.518	57%	0.571	S	S	.	*	H	α-helix	trans	-67.7	-39.8	172.3	-81.7	159.5	0	0	0	111.3	Q7 S14 I15	Q7-L11 WeakPolarHBondContact O-CB 3.5Å; Q7-L11 WeakPolarHBondContact O-CD1 3.37Å; Q7-L11 WeakPolarHBondContact O-CG 3.32Å; Q7-L11 PolarHBondContact O-N 2.95Å; L11-S14 WeakPolarHBondContact CA-OG 3.26Å; L11-S14 PolarHBondContact O-N 3.02Å; L11-S14 PolarHBondContact O-OG 3.33Å; L11-I15 WeakPolarHBondContact O-CB 3.45Å; L11-I15 VanDerWaalsContact O-CD1 3.29Å; L11-I15 WeakPolarHBondContact O-CD1 3.21Å; L11-I15 WeakPolarHBondContact O-CG1 3.45Å; L11-I15 PolarHBondContact O-N 3.26Å
12	N	37.5	Very low	49.1	Very low	105 Å²	105	98.4 Å²	98.4	56%	0.561	54%	0.544	S	S	*	.	H	α-helix	trans	-67.5	-39	174.1	-89.3	-7.7	0	0	0	112.9	T8 S9 I15 Q16	T8-N12 WeakPolarHBondContact O-CB 3.42Å; T8-N12 PolarHBondContact O-N 3.06Å; S9-N12 PolarHBondContact O-N 2.81Å; N12-I15 PolarHBondContact O-N 3.44Å; N12-Q16 WeakPolarHBondContact O-CB 3.5Å; N12-Q16 PolarHBondContact O-N 3.42Å
13	E	37.4	Very low	50.3	Low	113 Å²	113	96 Å²	96	53%	0.528	52%	0.524	S	S	.	.	H	α-helix	trans	-66.6	-36	175.3	-86.4	-165.7	166.7	0	0	113	S9 Q16 R17	S9-E13 PolarHBondContact O-N 2.97Å; E13-Q16 PolarHBondContact O-N 3.02Å; E13-R17 WeakPolarHBondContact O-CG 3.46Å; E13-R17 IonicContact OE2-NH2 3.83Å
14	S	39	Very low	51.4	Low	61 Å²	61	95.3 Å²	95.3	43%	0.427	52%	0.519	S	S	.	.	H	α-helix	trans	-74.4	-32	177.6	51	0	0	0	0	112.6	F10 L11 Q16 R17	F10-S14 WeakPolarHBondContact O-CB 3.48Å; F10-S14 PolarHBondContact O-N 3.49Å; F10-S14 PolarHBondContact O-OG 3.08Å; L11-S14 WeakPolarHBondContact CA-OG 3.26Å; L11-S14 PolarHBondContact O-N 3.02Å; L11-S14 PolarHBondContact O-OG 3.33Å; S14-Q16 PolarHBondContact O-N 3.36Å; S14-R17 PolarHBondContact O-N 3.21Å
15	I	44.9	Very low	53.1	Low	132 Å²	132	92.9 Å²	92.9	68%	0.677	50%	0.502	S	S	*	.	H	α-helix	trans	-67.6	-22.4	171.6	-68.3	165.2	0	0	0	111.6	L11 N12	L11-I15 WeakPolarHBondContact O-CB 3.45Å; L11-I15 VanDerWaalsContact O-CD1 3.29Å; L11-I15 WeakPolarHBondContact O-CD1 3.21Å; L11-I15 WeakPolarHBondContact O-CG1 3.45Å; L11-I15 PolarHBondContact O-N 3.26Å; N12-I15 PolarHBondContact O-N 3.44Å
16	Q	45.1	Very low	55.3	Low	166 Å²	166	90.1 Å²	90.1	78%	0.776	48%	0.484	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95.5	3	-177.8	-156.1	158.1	-21.1	0	0	114.6	N12 E13 S14	N12-Q16 WeakPolarHBondContact O-CB 3.5Å; N12-Q16 PolarHBondContact O-N 3.42Å; E13-Q16 PolarHBondContact O-N 3.02Å; S14-Q16 PolarHBondContact O-N 3.36Å
17	R	51.6	Low	57.4	Low	151 Å²	151	84.9 Å²	84.9	57%	0.57	46%	0.456	S	S	*	.	S	Bend	trans	-87.7	-1.4	-176.6	-83.4	177.3	-150	-168.7	4	116.1	E13 S14 Q267	E13-R17 WeakPolarHBondContact O-CG 3.46Å; E13-R17 IonicContact OE2-NH2 3.83Å; S14-R17 PolarHBondContact O-N 3.21Å; R17-Q267 VanDerWaalsContact O-O 3.07Å
18	G	61.8	Low	59.6	Low	47 Å²	47	79.6 Å²	79.6	49%	0.485	43%	0.431	S	S	.	.	S	Bend	trans	-103.3	149.5	178.4	0	0	0	0	0	112.8	S20	G18-S20 PolarHBondContact O-N 3.2Å
19	C	75.4	Confident	61.8	Low	18 Å²	18	83.1 Å²	83.1	12%	0.122	44%	0.437	C	S	.	.			trans	-67.7	116.6	176.8	-69.1	0	0	0	0	111.6	L21 C272	C19-L21 PolarHBondContact O-N 3.12Å; C19-L21 VanDerWaalsContact O-N 3.09Å; C19-C272 WeakPolarHBondContact CA-SG 3.49Å; C19-C272 HydrophobicContact CB-CB 3.8Å; C19-C272 WeakPolarHBondContact CB-SG 3.47Å; C19-C272 WeakPolarHBondContact SG-CA 3.47Å; C19-C272 WeakPolarHBondContact SG-CB 3.18Å; C19-C272 CovalentContact SG-SG 2.05Å; C19-C272 PolarHBondContact SG-SG 2.72Å
20	S	70.4	Confident	64.3	Low	79 Å²	79	83.4 Å²	83.4	55%	0.552	43%	0.43	S	S	*	.			trans	-71.8	100.2	167.3	161.6	0	0	0	0	109.7	G18 T22	G18-S20 PolarHBondContact O-N 3.2Å; S20-T22 PolarHBondContact O-N 2.94Å; S20-T22 PolarHBondContact O-OG1 3.46Å
21	L	68.8	Low	66.9	Low	60 Å²	60	76.8 Å²	76.8	31%	0.314	40%	0.401	S	S	.	.			trans	-61.6	112.1	-180	-150.5	84.7	0	0	0	110.8	C19 K23 N276 Y279	C19-L21 PolarHBondContact O-N 3.12Å; C19-L21 VanDerWaalsContact O-N 3.09Å; L21-K23 PolarHBondContact O-N 2.99Å; L21-N276 WeakPolarHBondContact CA-OD1 3.3Å; L21-Y279 HydrophobicContact CD1-CG 4.42Å; L21-Y279 HydrophobicContact CD2-CD1 3.64Å; L21-Y279 HydrophobicContact CD2-CD2 3.6Å; L21-Y279 HydrophobicContact CD2-CE1 3.81Å; L21-Y279 HydrophobicContact CD2-CE2 3.76Å; L21-Y279 HydrophobicContact CD2-CG 3.52Å; L21-Y279 HydrophobicContact CG-CD1 4.29Å; L21-Y279 HydrophobicContact CG-CG 4.24Å
22	T	64.6	Low	69.4	Low	83 Å²	83	72.1 Å²	72.1	51%	0.509	38%	0.376	S	S	.	.			trans	-86.7	102.3	-179	-54.4	0	0	0	0	108.4	S20 T24 N276	S20-T22 PolarHBondContact O-N 2.94Å; S20-T22 PolarHBondContact O-OG1 3.46Å; T22-T24 PolarHBondContact O-N 2.98Å; T22-N276 PolarHBondContact N-OD1 3.42Å
23	K	66.8	Low	72.2	Confident	69 Å²	69	71.5 Å²	71.5	30%	0.3	38%	0.377	S	S	.	.			trans	-68.7	104.4	172.2	-71.3	179.1	171.3	-176.8	0	107.9	L21 G25 Q27 F28 T92 Y279	L21-K23 PolarHBondContact O-N 2.99Å; K23-G25 PolarHBondContact O-N 3.37Å; K23-Q27 VanDerWaalsContact CD-NE2 3.33Å; K23-F28 HydrophobicContact CD-CZ 4.18Å; K23-T92 PolarHBondContact NZ-OG1 3.49Å; K23-Y279 HydrophobicContact CG-CE1 4.35Å
24	T	66.6	Low	75	Confident	102 Å²	102	66.9 Å²	66.9	63%	0.626	36%	0.356	S	S	*	.			trans	-64.5	4.1	177	38.7	0	0	0	0	114.3	T22 F26	T22-T24 PolarHBondContact O-N 2.98Å; T24-F26 PolarHBondContact O-N 3.39Å; T24-F26 WeakPolarHBondContact OG1-CD1 3.37Å; T24-F26 VanDerWaalsContact OG1-CE1 3.3Å; T24-F26 WeakPolarHBondContact OG1-CE1 3.44Å
25	G	80.4	Confident	77.8	Confident	19 Å²	19	64.1 Å²	64.1	20%	0.196	34%	0.336	C	S	.	.	S	Bend	trans	76.3	-26.3	174.7	0	0	0	0	0	115.4	K23 Q27 F28	K23-G25 PolarHBondContact O-N 3.37Å; G25-Q27 PolarHBondContact O-N 3.03Å; G25-Q27 VanDerWaalsContact O-N 3.12Å; G25-F28 WeakPolarHBondContact O-CB 3.22Å; G25-F28 VanDerWaalsContact O-CD2 3.26Å; G25-F28 WeakPolarHBondContact O-CD2 3.32Å; G25-F28 PolarHBondContact O-N 2.91Å
26	F	90.3	Very high	80.3	Confident	66 Å²	66	60.7 Å²	60.7	29%	0.289	32%	0.318	S	S	.	.	T	Hydrogen-bonded Turn	trans	-55.3	-35.1	-177	83	-79.9	0	0	0	113.3	T24 F28 Y29 Y30 A280 Q283 V284	T24-F26 PolarHBondContact O-N 3.39Å; T24-F26 WeakPolarHBondContact OG1-CD1 3.37Å; T24-F26 VanDerWaalsContact OG1-CE1 3.3Å; T24-F26 WeakPolarHBondContact OG1-CE1 3.44Å; F26-F28 PolarHBondContact O-N 3.28Å; F26-F28 VanDerWaalsContact O-N 3.13Å; F26-Y29 PolarHBondContact O-N 2.99Å; F26-Y30 HydrophobicContact CE2-CD1 4.44Å; F26-Y30 WeakPolarHBondContact O-CB 3.35Å; F26-Y30 PolarHBondContact O-N 3.13Å; F26-A280 HydrophobicContact CE1-CB 3.82Å; F26-A280 HydrophobicContact CZ-CB 3.92Å; F26-Q283 HydrophobicContact CE2-CB 4.5Å; F26-Q283 HydrophobicContact CZ-CB 4.1Å; F26-V284 HydrophobicContact CE2-CG2 4.13Å
27	Q	88.3	Confident	82.7	Confident	0 Å²	0	57.2 Å²	57.2	0%	0	30%	0.303	C	S	.	.	H	α-helix	trans	-59.4	-25.3	179.4	69.8	-169.2	11.3	0	0	113.2	K23 G25 Y29 L31 Y279 Q283	K23-Q27 VanDerWaalsContact CD-NE2 3.33Å; G25-Q27 PolarHBondContact O-N 3.03Å; G25-Q27 VanDerWaalsContact O-N 3.12Å; Q27-Y29 PolarHBondContact O-N 2.66Å; Q27-L31 HydrophobicContact CB-CD1 4.31Å; Q27-L31 WeakPolarHBondContact O-CB 3.34Å; Q27-L31 PolarHBondContact O-N 2.99Å; Q27-Y279 PolarHBondContact OE1-OH 3.48Å; Q27-Q283 HydrophobicContact CB-CB 4.4Å; Q27-Q283 HydrophobicContact CB-CG 4.15Å
28	F	90.1	Very high	84.8	Confident	29 Å²	29	50 Å²	50	13%	0.127	28%	0.276	C	S	.	.	H	α-helix	trans	-75.4	-10.8	176.5	-53.3	-48	0	0	0	113	K23 G25 F26 P32 Y88 K91 T92	K23-F28 HydrophobicContact CD-CZ 4.18Å; G25-F28 WeakPolarHBondContact O-CB 3.22Å; G25-F28 VanDerWaalsContact O-CD2 3.26Å; G25-F28 WeakPolarHBondContact O-CD2 3.32Å; G25-F28 PolarHBondContact O-N 2.91Å; F26-F28 PolarHBondContact O-N 3.28Å; F26-F28 VanDerWaalsContact O-N 3.13Å; F28-P32 WeakPolarHBondContact O-CG 3.27Å; F28-Y88 HydrophobicContact CD1-CD1 4.37Å; F28-K91 HydrophobicContact CD2-CD 4.2Å; F28-K91 HydrophobicContact CG-CD 4.33Å; F28-T92 HydrophobicContact CD1-CG2 4.1Å; F28-T92 HydrophobicContact CE1-CG2 3.58Å
29	Y	93.3	Very high	86.5	Confident	154 Å²	154	50.2 Å²	50.2	60%	0.604	26%	0.264	S	S	*	.	H	α-helix	trans	-112.2	-47.6	176	-60.1	-80.5	0	0	0	110.6	F26 Q27 T33	F26-Y29 PolarHBondContact O-N 2.99Å; Q27-Y29 PolarHBondContact O-N 2.66Å; Y29-T33 VanDerWaalsContact O-CB 3.31Å; Y29-T33 WeakPolarHBondContact O-CB 3.4Å; Y29-T33 PolarHBondContact O-N 3.49Å; Y29-T33 VanDerWaalsContact O-N 3.14Å; Y29-T33 PolarHBondContact O-OG1 3.42Å
30	Y	94.9	Very high	87.5	Confident	60 Å²	60	54.2 Å²	54.2	24%	0.235	28%	0.284	C	S	.	.	H	α-helix	trans	-60	-53.1	-178.9	169.8	-101.8	0	0	0	112.4	F26 T33 V34 V284	F26-Y30 HydrophobicContact CE2-CD1 4.44Å; F26-Y30 WeakPolarHBondContact O-CB 3.35Å; F26-Y30 PolarHBondContact O-N 3.13Å; Y30-T33 PolarHBondContact O-N 2.98Å; Y30-V34 HydrophobicContact CD2-CG2 4.07Å; Y30-V34 HydrophobicContact CE1-CG2 4.32Å; Y30-V34 HydrophobicContact CE2-CG2 3.6Å; Y30-V34 WeakPolarHBondContact O-CG2 3.32Å; Y30-V34 PolarHBondContact O-N 3.31Å; Y30-V284 HydrophobicContact CE1-CB 4.45Å; Y30-V284 HydrophobicContact CE1-CG2 4.44Å; Y30-V284 PolarHBondContact OH-O 3.26Å; Y30-V284 VanDerWaalsContact OH-O 3.06Å
31	L	94.9	Very high	88.6	Confident	0 Å²	0	53.7 Å²	53.7	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-66.9	-47.7	-174.6	-72.7	172.9	0	0	0	113	Q27 T33 V34 Y35 Y88 Q283	Q27-L31 HydrophobicContact CB-CD1 4.31Å; Q27-L31 WeakPolarHBondContact O-CB 3.34Å; Q27-L31 PolarHBondContact O-N 2.99Å; L31-T33 VanDerWaalsContact C-N 3.29Å; L31-T33 PolarHBondContact O-N 2.89Å; L31-V34 PolarHBondContact O-N 3.48Å; L31-Y35 HydrophobicContact CB-CD2 4.22Å; L31-Y35 HydrophobicContact CB-CE2 3.8Å; L31-Y35 HydrophobicContact CD2-CE2 4.12Å; L31-Y35 HydrophobicContact CG-CE2 4.43Å; L31-Y35 WeakPolarHBondContact O-CB 3.43Å; L31-Y35 WeakPolarHBondContact O-CD2 3.45Å; L31-Y35 PolarHBondContact O-N 2.96Å; L31-Y88 HydrophobicContact CB-CD1 4.26Å; L31-Y88 HydrophobicContact CB-CD2 4.04Å; L31-Y88 HydrophobicContact CB-CE1 4.32Å; L31-Y88 HydrophobicContact CB-CE2 4.13Å; L31-Y88 HydrophobicContact CB-CG 4.16Å; L31-Y88 HydrophobicContact CD1-CD1 4.13Å; L31-Y88 HydrophobicContact CD1-CD2 4.47Å; L31-Y88 HydrophobicContact CD1-CE1 3.4Å; L31-Y88 HydrophobicContact CD1-CE2 3.83Å; L31-Y88 VanDerWaalsContact CD1-OH 3.32Å; L31-Y88 WeakPolarHBondContact CD1-OH 3.47Å; L31-Y88 HydrophobicContact CG-CE1 4.47Å; L31-Q283 HydrophobicContact CD1-CB 4.32Å; L31-Q283 WeakPolarHBondContact CD2-O 3.41Å
32	P	95.8	Very high	89.8	Confident	1 Å²	1	50.8 Å²	50.8	1%	0.006	26%	0.262	C	S	.	.	H	α-helix	trans	-53.9	-44.6	171.2	-30.2	37	0	0	0	113.3	F28 V34 Y35 I36 Y88 F89	F28-P32 WeakPolarHBondContact O-CG 3.27Å; P32-V34 PolarHBondContact O-N 3.15Å; P32-Y35 PolarHBondContact O-N 3.36Å; P32-I36 WeakPolarHBondContact O-CB 3.3Å; P32-I36 WeakPolarHBondContact O-CD1 3.33Å; P32-I36 WeakPolarHBondContact O-CG1 3.47Å; P32-I36 PolarHBondContact O-N 3.2Å; P32-Y88 HydrophobicContact CG-CG 4.3Å; P32-F89 HydrophobicContact CB-CD2 4.37Å; P32-F89 HydrophobicContact CB-CE1 4.09Å; P32-F89 HydrophobicContact CB-CE2 3.97Å; P32-F89 HydrophobicContact CB-CZ 3.8Å
33	T	96.7	Very high	91.2	Very high	92 Å²	92	49.2 Å²	49.2	56%	0.564	25%	0.25	S	C	*	.	H	α-helix	trans	-61.5	-48.3	-178.4	-58.1	0	0	0	0	110.9	Y29 Y30 L31 I36 M37	Y29-T33 VanDerWaalsContact O-CB 3.31Å; Y29-T33 WeakPolarHBondContact O-CB 3.4Å; Y29-T33 PolarHBondContact O-N 3.49Å; Y29-T33 VanDerWaalsContact O-N 3.14Å; Y29-T33 PolarHBondContact O-OG1 3.42Å; Y30-T33 PolarHBondContact O-N 2.98Å; L31-T33 VanDerWaalsContact C-N 3.29Å; L31-T33 PolarHBondContact O-N 2.89Å; T33-I36 PolarHBondContact O-N 2.66Å; T33-M37 PolarHBondContact O-N 2.92Å
34	V	96.3	Very high	92.5	Very high	16 Å²	16	50.7 Å²	50.7	10%	0.097	27%	0.265	C	S	.	.	H	α-helix	trans	-61.5	-47.6	175.9	173.9	0	0	0	0	110.6	Y30 L31 P32 I36 M37 V38 L291	Y30-V34 HydrophobicContact CD2-CG2 4.07Å; Y30-V34 HydrophobicContact CE1-CG2 4.32Å; Y30-V34 HydrophobicContact CE2-CG2 3.6Å; Y30-V34 WeakPolarHBondContact O-CG2 3.32Å; Y30-V34 PolarHBondContact O-N 3.31Å; L31-V34 PolarHBondContact O-N 3.48Å; P32-V34 PolarHBondContact O-N 3.15Å; V34-I36 PolarHBondContact O-N 2.91Å; V34-M37 WeakPolarHBondContact O-CB 3.24Å; V34-M37 PolarHBondContact O-N 2.91Å; V34-V38 HydrophobicContact CG1-CG2 4.18Å; V34-V38 VanDerWaalsContact O-CG2 3.24Å; V34-V38 WeakPolarHBondContact O-CG2 3.26Å; V34-V38 PolarHBondContact O-N 3.04Å; V34-L291 HydrophobicContact CG1-CD2 4.14Å; V34-L291 HydrophobicContact CG1-CG 4.49Å
35	Y	96.9	Very high	93.7	Very high	2 Å²	2	46.4 Å²	46.4	1%	0.008	24%	0.24	C	C	.	.	H	α-helix	trans	-66.6	-33.1	-178.9	-63.8	-32.4	0	0	0	113.6	L31 P32 V38 F39 L81 L84 Y88 S290	L31-Y35 HydrophobicContact CB-CD2 4.22Å; L31-Y35 HydrophobicContact CB-CE2 3.8Å; L31-Y35 HydrophobicContact CD2-CE2 4.12Å; L31-Y35 HydrophobicContact CG-CE2 4.43Å; L31-Y35 WeakPolarHBondContact O-CB 3.43Å; L31-Y35 WeakPolarHBondContact O-CD2 3.45Å; L31-Y35 PolarHBondContact O-N 2.96Å; P32-Y35 PolarHBondContact O-N 3.36Å; Y35-V38 PolarHBondContact O-N 3.46Å; Y35-F39 WeakPolarHBondContact O-CB 3.48Å; Y35-F39 PolarHBondContact O-N 3.38Å; Y35-L81 HydrophobicContact CD1-CD2 3.97Å; Y35-L81 HydrophobicContact CG-CD2 4.19Å; Y35-L84 HydrophobicContact CD2-CB 4.37Å; Y35-L84 HydrophobicContact CD2-CD2 3.82Å; Y35-L84 HydrophobicContact CD2-CG 3.93Å; Y35-L84 HydrophobicContact CE1-CD2 4.14Å; Y35-L84 HydrophobicContact CE2-CB 4.46Å; Y35-L84 HydrophobicContact CE2-CD2 3.23Å; Y35-L84 HydrophobicContact CE2-CG 3.56Å; Y35-L84 HydrophobicContact CG-CD2 4.49Å; Y35-L84 VanDerWaalsContact CZ-CD2 3.4Å; Y35-Y88 HydrophobicContact CD2-CD2 4.3Å; Y35-Y88 AromaticContact CE2-CD2 3.91Å; Y35-Y88 HydrophobicContact CE2-CD2 3.91Å; Y35-Y88 AromaticContact CE2-CE2 3.74Å; Y35-Y88 HydrophobicContact CE2-CE2 3.74Å; Y35-S290 WeakPolarHBondContact CE1-OG 3.09Å
36	I	97.6	Very high	94.4	Very high	60 Å²	60	45.5 Å²	45.5	31%	0.308	23%	0.231	S	C	.	.	H	α-helix	trans	-65	-47.4	172.3	-71.3	162.7	0	0	0	109.8	P32 T33 V34 V38 F39 L40 I85 F89	P32-I36 WeakPolarHBondContact O-CB 3.3Å; P32-I36 WeakPolarHBondContact O-CD1 3.33Å; P32-I36 WeakPolarHBondContact O-CG1 3.47Å; P32-I36 PolarHBondContact O-N 3.2Å; T33-I36 PolarHBondContact O-N 2.66Å; V34-I36 PolarHBondContact O-N 2.91Å; I36-V38 VanDerWaalsContact C-N 3.3Å; I36-V38 PolarHBondContact O-N 3.47Å; I36-F39 PolarHBondContact O-N 3.04Å; I36-L40 HydrophobicContact CG2-CD1 4.01Å; I36-L40 HydrophobicContact CG2-CG 4.43Å; I36-L40 WeakPolarHBondContact O-CG 3.34Å; I36-L40 PolarHBondContact O-N 3.24Å; I36-I85 HydrophobicContact CD1-CG2 4.19Å; I36-I85 HydrophobicContact CG1-CD1 3.83Å; I36-I85 HydrophobicContact CG1-CG1 4.16Å; I36-I85 HydrophobicContact CG1-CG2 3.91Å; I36-F89 HydrophobicContact CD1-CE2 3.96Å; I36-F89 HydrophobicContact CD1-CZ 3.98Å
37	M	96.1	Very high	94.6	Very high	93 Å²	93	44.5 Å²	44.5	46%	0.458	23%	0.233	S	C	.	.	H	α-helix	trans	-58.9	-45.3	176.6	-177.3	-173.8	69.2	0	0	111	T33 V34 F39 L40 T41 L291	T33-M37 PolarHBondContact O-N 2.92Å; V34-M37 WeakPolarHBondContact O-CB 3.24Å; V34-M37 PolarHBondContact O-N 2.91Å; M37-F39 VanDerWaalsContact C-N 3.34Å; M37-L40 PolarHBondContact O-N 3.3Å; M37-T41 WeakPolarHBondContact O-CB 3.29Å; M37-T41 WeakPolarHBondContact O-CG2 3.24Å; M37-T41 PolarHBondContact O-N 3.47Å; M37-T41 PolarHBondContact O-OG1 3.05Å; M37-L291 HydrophobicContact CE-CD2 3.2Å
38	V	95.9	Very high	94.7	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-64.2	-40.9	177.1	173.8	0	0	0	0	111.4	V34 Y35 I36 G42 V78 L81 S290 L291 C294	V34-V38 HydrophobicContact CG1-CG2 4.18Å; V34-V38 VanDerWaalsContact O-CG2 3.24Å; V34-V38 WeakPolarHBondContact O-CG2 3.26Å; V34-V38 PolarHBondContact O-N 3.04Å; Y35-V38 PolarHBondContact O-N 3.46Å; I36-V38 VanDerWaalsContact C-N 3.3Å; I36-V38 PolarHBondContact O-N 3.47Å; V38-G42 VanDerWaalsContact O-CA 3.25Å; V38-G42 WeakPolarHBondContact O-CA 3.4Å; V38-G42 PolarHBondContact O-N 2.89Å; V38-V78 HydrophobicContact CG1-CG2 4.49Å; V38-L81 HydrophobicContact CB-CD1 3.93Å; V38-L81 HydrophobicContact CG1-CD1 3.47Å; V38-L81 VanDerWaalsContact CG1-CD1 3.47Å; V38-S290 VanDerWaalsContact CG1-O 3.31Å; V38-S290 WeakPolarHBondContact CG1-O 3.39Å; V38-L291 HydrophobicContact CG2-CD2 3.75Å; V38-C294 WeakPolarHBondContact CA-SG 3.36Å
39	F	96.9	Very high	94.7	Very high	52 Å²	52	45.8 Å²	45.8	23%	0.228	24%	0.241	C	C	.	.	H	α-helix	trans	-60.1	-53.1	177.8	175.9	-108	0	0	0	111.1	Y35 I36 M37 L43 V78 L81 P82 I85	Y35-F39 WeakPolarHBondContact O-CB 3.48Å; Y35-F39 PolarHBondContact O-N 3.38Å; I36-F39 PolarHBondContact O-N 3.04Å; M37-F39 VanDerWaalsContact C-N 3.34Å; F39-L43 HydrophobicContact CE1-CD2 4.41Å; F39-L43 HydrophobicContact CE2-CD2 4.34Å; F39-L43 HydrophobicContact CZ-CD2 3.96Å; F39-L43 WeakPolarHBondContact O-CB 3.27Å; F39-L43 PolarHBondContact O-N 3.44Å; F39-V78 HydrophobicContact CD2-CG1 3.89Å; F39-V78 WeakPolarHBondContact CD2-O 3.42Å; F39-V78 HydrophobicContact CE2-CG1 4.43Å; F39-L81 HydrophobicContact CB-CB 4.32Å; F39-L81 HydrophobicContact CB-CD1 4.14Å; F39-L81 HydrophobicContact CD2-CB 4.4Å; F39-P82 HydrophobicContact CD2-CG 4.1Å; F39-P82 HydrophobicContact CE2-CG 3.75Å; F39-P82 HydrophobicContact CZ-CG 4.14Å; F39-I85 HydrophobicContact CB-CD1 4.27Å
40	L	95.7	Very high	94.7	Very high	102 Å²	102	40 Å²	40	53%	0.534	22%	0.22	S	C	.	.	H	α-helix	trans	-64.9	-51	-177.2	-64.7	175.6	0	0	0	111.9	I36 M37 V44	I36-L40 HydrophobicContact CG2-CD1 4.01Å; I36-L40 HydrophobicContact CG2-CG 4.43Å; I36-L40 WeakPolarHBondContact O-CG 3.34Å; I36-L40 PolarHBondContact O-N 3.24Å; M37-L40 PolarHBondContact O-N 3.3Å; L40-V44 WeakPolarHBondContact O-CG2 3.21Å; L40-V44 PolarHBondContact O-N 2.88Å
41	T	93.6	Very high	94.6	Very high	67 Å²	67	42 Å²	42	41%	0.411	23%	0.227	S	C	.	.	H	α-helix	trans	-71.2	-42.3	-176.8	56.4	0	0	0	0	112	M37 G45 C294	M37-T41 WeakPolarHBondContact O-CB 3.29Å; M37-T41 WeakPolarHBondContact O-CG2 3.24Å; M37-T41 PolarHBondContact O-N 3.47Å; M37-T41 PolarHBondContact O-OG1 3.05Å; T41-G45 PolarHBondContact O-N 3Å; T41-C294 PolarHBondContact OG1-SG 3.11Å
42	G	94.3	Very high	94.3	Very high	0 Å²	0	42 Å²	42	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-66.8	-38.1	177.3	0	0	0	0	0	112.7	V38 N46	V38-G42 VanDerWaalsContact O-CA 3.25Å; V38-G42 WeakPolarHBondContact O-CA 3.4Å; V38-G42 PolarHBondContact O-N 2.89Å; G42-N46 VanDerWaalsContact O-CB 3.24Å; G42-N46 WeakPolarHBondContact O-CB 3.25Å; G42-N46 PolarHBondContact O-N 3.14Å; G42-N46 PolarHBondContact O-ND2 2.99Å
43	L	94.8	Very high	93.9	Very high	49 Å²	49	42 Å²	42	26%	0.257	23%	0.227	S	C	.	.	H	α-helix	trans	-66.1	-49.7	-179.7	-176.2	70.8	0	0	0	110	F39 S47 F75 V78 L79	F39-L43 HydrophobicContact CE1-CD2 4.41Å; F39-L43 HydrophobicContact CE2-CD2 4.34Å; F39-L43 HydrophobicContact CZ-CD2 3.96Å; F39-L43 WeakPolarHBondContact O-CB 3.27Å; F39-L43 PolarHBondContact O-N 3.44Å; L43-S47 WeakPolarHBondContact O-CB 3.18Å; L43-S47 PolarHBondContact O-N 3.09Å; L43-S47 PolarHBondContact O-OG 2.87Å; L43-F75 HydrophobicContact CD1-CD2 4.35Å; L43-F75 HydrophobicContact CD1-CE2 3.71Å; L43-V78 HydrophobicContact CB-CG1 3.88Å; L43-V78 HydrophobicContact CD1-CG1 4.38Å; L43-L79 HydrophobicContact CD1-CD2 3.95Å
44	V	93.6	Very high	93.6	Very high	101 Å²	101	40.4 Å²	40.4	61%	0.612	22%	0.217	S	C	*	.	H	α-helix	trans	-64.1	-50.8	178.1	175.1	0	0	0	0	110.8	L40 L48	L40-V44 WeakPolarHBondContact O-CG2 3.21Å; L40-V44 PolarHBondContact O-N 2.88Å; V44-L48 VanDerWaalsContact O-CB 3.25Å; V44-L48 WeakPolarHBondContact O-CB 3.34Å; V44-L48 PolarHBondContact O-N 3.21Å
45	G	91.6	Very high	93.2	Very high	11 Å²	11	43.2 Å²	43.2	11%	0.113	24%	0.236	C	C	.	.	H	α-helix	trans	-62.4	-50.2	-175.7	0	0	0	0	0	113.2	T41 A49	T41-G45 PolarHBondContact O-N 3Å; G45-A49 WeakPolarHBondContact O-CB 3.27Å; G45-A49 PolarHBondContact O-N 3.09Å
46	N	94.3	Very high	92.5	Very high	0 Å²	0	46 Å²	46	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-74.8	-33.9	-177.9	-65.9	-64.8	0	0	0	112.2	G42 A49 I50 F75 S293	G42-N46 VanDerWaalsContact O-CB 3.24Å; G42-N46 WeakPolarHBondContact O-CB 3.25Å; G42-N46 PolarHBondContact O-N 3.14Å; G42-N46 PolarHBondContact O-ND2 2.99Å; N46-A49 PolarHBondContact O-N 3.37Å; N46-I50 WeakPolarHBondContact O-CB 3.44Å; N46-I50 VanDerWaalsContact O-CG1 3.27Å; N46-I50 WeakPolarHBondContact O-CG1 3.34Å; N46-I50 PolarHBondContact O-N 3.29Å; N46-F75 HydrophobicContact CB-CB 4.12Å; N46-S293 PolarHBondContact ND2-O 2.78Å
47	S	94.1	Very high	91.6	Very high	46 Å²	46	44.1 Å²	44.1	32%	0.322	24%	0.24	S	C	.	.	H	α-helix	trans	-62.5	-45.7	173	-65.3	0	0	0	0	111.5	L43 A49 I50 W51 F75	L43-S47 WeakPolarHBondContact O-CB 3.18Å; L43-S47 PolarHBondContact O-N 3.09Å; L43-S47 PolarHBondContact O-OG 2.87Å; S47-A49 VanDerWaalsContact C-N 3.32Å; S47-A49 PolarHBondContact O-N 2.82Å; S47-I50 PolarHBondContact O-N 2.74Å; S47-W51 WeakPolarHBondContact O-CB 3.42Å; S47-W51 PolarHBondContact O-N 2.95Å; S47-F75 WeakPolarHBondContact OG-CE2 3.06Å
48	L	91.3	Very high	90.9	Very high	56 Å²	56	48.2 Å²	48.2	29%	0.293	25%	0.25	S	C	.	.	H	α-helix	trans	-61.7	-41.5	175.7	179	59.8	0	0	0	111.4	V44 W51 M52 F301 L311	V44-L48 VanDerWaalsContact O-CB 3.25Å; V44-L48 WeakPolarHBondContact O-CB 3.34Å; V44-L48 PolarHBondContact O-N 3.21Å; L48-W51 HydrophobicContact CD1-CE3 3.77Å; L48-W51 HydrophobicContact CD1-CZ3 4Å; L48-M52 HydrophobicContact CD1-CG 4.37Å; L48-M52 WeakPolarHBondContact O-CB 3.34Å; L48-M52 VanDerWaalsContact O-CG 3.3Å; L48-M52 WeakPolarHBondContact O-CG 3.29Å; L48-M52 PolarHBondContact O-N 3.21Å; L48-F301 HydrophobicContact CD2-CE1 4.21Å; L48-F301 HydrophobicContact CD2-CZ 3.71Å; L48-F301 HydrophobicContact CG-CZ 4.22Å; L48-L311 HydrophobicContact CD1-CD1 4.14Å
49	A	90.3	Very high	90.3	Very high	0 Å²	0	54.1 Å²	54.1	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-62	-50.6	176.3	0	0	0	0	0	112	G45 N46 S47 W51 M52 F53 A71 Y300	G45-A49 WeakPolarHBondContact O-CB 3.27Å; G45-A49 PolarHBondContact O-N 3.09Å; N46-A49 PolarHBondContact O-N 3.37Å; S47-A49 VanDerWaalsContact C-N 3.32Å; S47-A49 PolarHBondContact O-N 2.82Å; A49-W51 PolarHBondContact O-N 3.5Å; A49-M52 PolarHBondContact O-N 3.4Å; A49-F53 HydrophobicContact CB-CE2 4.38Å; A49-F53 WeakPolarHBondContact O-CD2 3.36Å; A49-F53 PolarHBondContact O-N 2.95Å; A49-A71 HydrophobicContact CB-CB 4.24Å; A49-Y300 HydrophobicContact CB-CD2 3.6Å; A49-Y300 HydrophobicContact CB-CE2 3.95Å
50	I	93.4	Very high	89.6	Confident	33 Å²	33	54 Å²	54	17%	0.169	29%	0.286	C	S	.	.	H	α-helix	trans	-58.2	-48.8	178.1	-71.6	168.1	0	0	0	110.4	N46 S47 M52 F53 V54 F68 A71 F75	N46-I50 WeakPolarHBondContact O-CB 3.44Å; N46-I50 VanDerWaalsContact O-CG1 3.27Å; N46-I50 WeakPolarHBondContact O-CG1 3.34Å; N46-I50 PolarHBondContact O-N 3.29Å; S47-I50 PolarHBondContact O-N 2.74Å; I50-M52 VanDerWaalsContact C-N 3.35Å; I50-M52 PolarHBondContact O-N 2.91Å; I50-F53 PolarHBondContact O-N 3.41Å; I50-V54 HydrophobicContact CG2-CG2 4.46Å; I50-V54 WeakPolarHBondContact O-CG2 3.46Å; I50-V54 PolarHBondContact O-N 3.46Å; I50-F68 HydrophobicContact CG1-CE2 4.47Å; I50-F68 HydrophobicContact CG2-CE2 4.17Å; I50-A71 HydrophobicContact CG1-CB 4.11Å; I50-F75 HydrophobicContact CD1-CB 3.72Å; I50-F75 HydrophobicContact CD1-CD1 4.2Å; I50-F75 HydrophobicContact CD1-CD2 4.42Å; I50-F75 HydrophobicContact CD1-CG 3.87Å
51	W	92.4	Very high	89.1	Confident	100 Å²	100	51.8 Å²	51.8	38%	0.379	28%	0.279	S	S	.	.	H	α-helix	trans	-57.5	-46.4	176.8	174.1	72.9	0	0	0	111.9	S47 L48 A49 F53 V54 C55 H56 A314	S47-W51 WeakPolarHBondContact O-CB 3.42Å; S47-W51 PolarHBondContact O-N 2.95Å; L48-W51 HydrophobicContact CD1-CE3 3.77Å; L48-W51 HydrophobicContact CD1-CZ3 4Å; A49-W51 PolarHBondContact O-N 3.5Å; W51-F53 PolarHBondContact O-N 3.36Å; W51-V54 PolarHBondContact O-N 2.8Å; W51-C55 VanDerWaalsContact CD1-SG 3.6Å; W51-C55 VanDerWaalsContact O-CB 3.27Å; W51-C55 WeakPolarHBondContact O-CB 3.34Å; W51-C55 PolarHBondContact O-N 2.99Å; W51-H56 AromaticContact CE2-NE2 3.91Å; W51-H56 AromaticContact CH2-CD2 3.86Å; W51-H56 AromaticContact CH2-NE2 3.47Å; W51-H56 WeakPolarHBondContact CH2-NE2 3.39Å; W51-H56 AromaticContact CZ2-CD2 3.93Å; W51-H56 AromaticContact CZ2-NE2 3.32Å; W51-H56 VanDerWaalsContact CZ2-NE2 3.32Å; W51-H56 WeakPolarHBondContact CZ2-NE2 3.28Å; W51-A314 HydrophobicContact CH2-CB 4.17Å
52	M	87.9	Confident	88.7	Confident	0 Å²	0	49 Å²	49	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-60.9	-44.5	176.8	-81.3	-65.6	-62.1	0	0	112.5	L48 A49 I50 H56 M57 F307 K310 L311 A314	L48-M52 HydrophobicContact CD1-CG 4.37Å; L48-M52 WeakPolarHBondContact O-CB 3.34Å; L48-M52 VanDerWaalsContact O-CG 3.3Å; L48-M52 WeakPolarHBondContact O-CG 3.29Å; L48-M52 PolarHBondContact O-N 3.21Å; A49-M52 PolarHBondContact O-N 3.4Å; I50-M52 VanDerWaalsContact C-N 3.35Å; I50-M52 PolarHBondContact O-N 2.91Å; M52-H56 HydrophobicContact CE-CB 4.03Å; M52-H56 CarbonylContact O-C 3.59Å; M52-H56 WeakPolarHBondContact O-CA 3.49Å; M52-H56 WeakPolarHBondContact O-CB 3.36Å; M52-H56 PolarHBondContact O-N 3.38Å; M52-H56 HydrophobicContact SD-CB 4.1Å; M52-M57 WeakPolarHBondContact O-CG 2.99Å; M52-M57 PolarHBondContact O-N 3.23Å; M52-F307 HydrophobicContact CB-CE1 4.22Å; M52-F307 HydrophobicContact CB-CE2 3.48Å; M52-F307 VanDerWaalsContact CB-CE2 3.48Å; M52-F307 HydrophobicContact CB-CZ 3.31Å; M52-F307 HydrophobicContact CE-CD1 4.35Å; M52-F307 HydrophobicContact CE-CE1 4.15Å; M52-F307 HydrophobicContact CE-CE2 4.46Å; M52-F307 HydrophobicContact CE-CZ 4.24Å; M52-F307 HydrophobicContact CG-CE1 3.9Å; M52-F307 HydrophobicContact CG-CE2 4.11Å; M52-F307 HydrophobicContact CG-CZ 3.44Å; M52-F307 VanDerWaalsContact CG-CZ 3.44Å; M52-K310 HydrophobicContact CE-CB 3.94Å; M52-L311 HydrophobicContact CE-CB 3.85Å; M52-L311 HydrophobicContact CE-CD1 4.33Å; M52-L311 HydrophobicContact CG-CD1 4.06Å; M52-L311 HydrophobicContact SD-CB 4.25Å; M52-L311 HydrophobicContact SD-CD1 3.64Å; M52-A314 HydrophobicContact SD-CB 4.47Å
53	F	88.7	Confident	88.2	Confident	1 Å²	1	49.7 Å²	49.7	0%	0.004	27%	0.266	C	S	.	.	H	α-helix	trans	-61.1	-47.8	177.9	-78.2	-59.6	0	0	0	111.6	A49 I50 W51 M57 W60 M67 F68	A49-F53 HydrophobicContact CB-CE2 4.38Å; A49-F53 WeakPolarHBondContact O-CD2 3.36Å; A49-F53 PolarHBondContact O-N 2.95Å; I50-F53 PolarHBondContact O-N 3.41Å; W51-F53 PolarHBondContact O-N 3.36Å; F53-M57 HydrophobicContact CD1-CB 4.27Å; F53-M57 HydrophobicContact CD1-CE 4.39Å; F53-M57 HydrophobicContact CD1-CG 4.33Å; F53-M57 HydrophobicContact CD1-SD 3.39Å; F53-M57 WeakPolarHBondContact CD1-SD 3.01Å; F53-M57 HydrophobicContact CE1-CE 4.07Å; F53-M57 HydrophobicContact CE1-SD 3.42Å; F53-M57 WeakPolarHBondContact CE1-SD 3.24Å; F53-M57 HydrophobicContact CG-SD 4.27Å; F53-M57 HydrophobicContact CZ-SD 4.34Å; F53-W60 HydrophobicContact CB-CZ2 3.99Å; F53-W60 PolarHBondContact O-NE1 2.94Å; F53-M67 HydrophobicContact CE1-CB 4.29Å; F53-M67 HydrophobicContact CE2-CB 4.16Å; F53-M67 HydrophobicContact CZ-CB 3.55Å; F53-F68 HydrophobicContact CB-CD2 3.65Å; F53-F68 HydrophobicContact CB-CE2 4.37Å; F53-F68 HydrophobicContact CD2-CB 4.16Å; F53-F68 HydrophobicContact CD2-CD2 4.05Å; F53-F68 HydrophobicContact CG-CB 4.21Å; F53-F68 HydrophobicContact CG-CD2 4.06Å
54	V	90.4	Very high	87.9	Confident	60 Å²	60	47.8 Å²	47.8	36%	0.364	26%	0.257	S	S	.	.	H	α-helix	trans	-69.8	-49.2	-176.4	174.4	0	0	0	0	111.7	I50 W51 R58 F68	I50-V54 HydrophobicContact CG2-CG2 4.46Å; I50-V54 WeakPolarHBondContact O-CG2 3.46Å; I50-V54 PolarHBondContact O-N 3.46Å; W51-V54 PolarHBondContact O-N 2.8Å; V54-R58 PolarHBondContact O-NE 2.87Å; V54-F68 HydrophobicContact CG2-CE2 3.97Å
55	C	87.3	Confident	87.8	Confident	74 Å²	74	43.2 Å²	43.2	50%	0.5	23%	0.229	S	C	.	.	H	α-helix	trans	-92	-28.1	-168.6	-61.4	0	0	0	0	114.1	W51	W51-C55 VanDerWaalsContact CD1-SG 3.6Å; W51-C55 VanDerWaalsContact O-CB 3.27Å; W51-C55 WeakPolarHBondContact O-CB 3.34Å; W51-C55 PolarHBondContact O-N 2.99Å
56	H	82.4	Confident	87.9	Confident	61 Å²	61	43.7 Å²	43.7	28%	0.282	23%	0.228	S	C	.	.	T	Hydrogen-bonded Turn	trans	-124	-19	-168.2	-65.2	-60	0	0	0	114.7	W51 M52 K310 A314	W51-H56 AromaticContact CE2-NE2 3.91Å; W51-H56 AromaticContact CH2-CD2 3.86Å; W51-H56 AromaticContact CH2-NE2 3.47Å; W51-H56 WeakPolarHBondContact CH2-NE2 3.39Å; W51-H56 AromaticContact CZ2-CD2 3.93Å; W51-H56 AromaticContact CZ2-NE2 3.32Å; W51-H56 VanDerWaalsContact CZ2-NE2 3.32Å; W51-H56 WeakPolarHBondContact CZ2-NE2 3.28Å; M52-H56 HydrophobicContact CE-CB 4.03Å; M52-H56 CarbonylContact O-C 3.59Å; M52-H56 WeakPolarHBondContact O-CA 3.49Å; M52-H56 WeakPolarHBondContact O-CB 3.36Å; M52-H56 PolarHBondContact O-N 3.38Å; M52-H56 HydrophobicContact SD-CB 4.1Å; H56-K310 VanDerWaalsContact O-CD 3.26Å; H56-K310 WeakPolarHBondContact O-CD 3.36Å; H56-K310 WeakPolarHBondContact O-CE 3.33Å; H56-K310 PolarHBondContact O-NZ 2.81Å; H56-A314 WeakPolarHBondContact NE2-CB 3.04Å
57	M	79.3	Confident	87.7	Confident	21 Å²	21	44.4 Å²	44.4	10%	0.103	23%	0.231	C	C	.	.			trans	-98.6	10.4	-173	-64.5	-165.6	73.7	0	0	116.2	M52 F53 P59 F307 K310	M52-M57 WeakPolarHBondContact O-CG 2.99Å; M52-M57 PolarHBondContact O-N 3.23Å; F53-M57 HydrophobicContact CD1-CB 4.27Å; F53-M57 HydrophobicContact CD1-CE 4.39Å; F53-M57 HydrophobicContact CD1-CG 4.33Å; F53-M57 HydrophobicContact CD1-SD 3.39Å; F53-M57 WeakPolarHBondContact CD1-SD 3.01Å; F53-M57 HydrophobicContact CE1-CE 4.07Å; F53-M57 HydrophobicContact CE1-SD 3.42Å; F53-M57 WeakPolarHBondContact CE1-SD 3.24Å; F53-M57 HydrophobicContact CG-SD 4.27Å; F53-M57 HydrophobicContact CZ-SD 4.34Å; M57-P59 CarbonylContact O-C 3.56Å; M57-P59 VanDerWaalsContact O-C 3.26Å; M57-F307 HydrophobicContact CE-CD2 4.17Å; M57-F307 HydrophobicContact SD-CD2 3.36Å; M57-F307 WeakPolarHBondContact SD-CD2 3.44Å; M57-F307 HydrophobicContact SD-CE2 3.8Å; M57-F307 HydrophobicContact SD-CG 4.41Å; M57-K310 HydrophobicContact CG-CD 4.4Å
58	R	80.2	Confident	87.7	Confident	178 Å²	178	44 Å²	44	67%	0.672	22%	0.224	S	C	*	.	P	Polyproline II helix	trans	-70.3	142	173.6	-64.1	-174.1	-178.8	-161.9	-2.1	111.7	V54	V54-R58 PolarHBondContact O-NE 2.87Å
59	P	83.4	Confident	87.9	Confident	125 Å²	125	42.3 Å²	42.3	81%	0.812	22%	0.215	S	C	*	.	S	Bend	cis	-72.3	145.4	-11	32	-34.8	0	0	0	112.3	M57	M57-P59 CarbonylContact O-C 3.56Å; M57-P59 VanDerWaalsContact O-C 3.26Å
60	W	83.6	Confident	88	Confident	48 Å²	48	42.3 Å²	42.3	18%	0.182	22%	0.215	C	C	.	.	P	Polyproline II helix	trans	-76.4	133.6	-177	-67.7	8.1	0	0	0	112.2	F53 V65 F68	F53-W60 HydrophobicContact CB-CZ2 3.99Å; F53-W60 PolarHBondContact O-NE1 2.94Å; W60-V65 HydrophobicContact CE3-CG2 4.21Å; W60-F68 HydrophobicContact CH2-CB 4.01Å; W60-F68 AromaticContact CH2-CD1 3.62Å; W60-F68 HydrophobicContact CH2-CD1 3.62Å; W60-F68 AromaticContact CH2-CD2 3.53Å; W60-F68 HydrophobicContact CH2-CD2 3.53Å; W60-F68 AromaticContact CH2-CE1 3.92Å; W60-F68 HydrophobicContact CH2-CE1 3.92Å; W60-F68 AromaticContact CH2-CE2 3.82Å; W60-F68 HydrophobicContact CH2-CE2 3.82Å; W60-F68 AromaticContact CH2-CG 3.41Å; W60-F68 HydrophobicContact CH2-CG 3.41Å; W60-F68 VanDerWaalsContact CH2-CG 3.41Å; W60-F68 HydrophobicContact CH2-CZ 4.01Å; W60-F68 HydrophobicContact CZ2-CD2 4.17Å; W60-F68 HydrophobicContact CZ2-CE2 4.43Å; W60-F68 HydrophobicContact CZ2-CG 4.39Å; W60-F68 HydrophobicContact CZ3-CB 3.85Å; W60-F68 AromaticContact CZ3-CD1 3.7Å; W60-F68 HydrophobicContact CZ3-CD1 3.7Å; W60-F68 HydrophobicContact CZ3-CD2 4.23Å; W60-F68 HydrophobicContact CZ3-CE1 4.32Å; W60-F68 AromaticContact CZ3-CG 3.64Å; W60-F68 HydrophobicContact CZ3-CG 3.64Å
61	S	84.3	Confident	88.1	Confident	56 Å²	56	40.7 Å²	40.7	39%	0.392	21%	0.207	S	C	.	.	P	Polyproline II helix	trans	-77.2	162.6	166	75.4	0	0	0	0	111.1	I63 S64 V65	S61-I63 VanDerWaalsContact C-N 3.34Å; S61-I63 PolarHBondContact O-N 3.04Å; S61-I63 VanDerWaalsContact OG-CG2 3.29Å; S61-I63 WeakPolarHBondContact OG-CG2 3.43Å; S61-S64 WeakPolarHBondContact O-CB 3.21Å; S61-S64 PolarHBondContact O-N 3.46Å; S61-S64 VanDerWaalsContact O-N 3.07Å; S61-S64 PolarHBondContact OG-N 2.97Å; S61-S64 PolarHBondContact OG-OG 3.11Å; S61-V65 PolarHBondContact O-N 3.46Å
62	S	85.4	Confident	88.3	Confident	8 Å²	8	38.8 Å²	38.8	6%	0.056	20%	0.204	C	C	.	.	H	α-helix	trans	-58.9	-41.6	179.1	-62.8	0	0	0	0	113.3	S64 V65 H125 L140 K141 K142 A145	S62-S64 VanDerWaalsContact C-N 3.33Å; S62-S64 PolarHBondContact O-N 2.8Å; S62-V65 WeakPolarHBondContact O-CB 3.29Å; S62-V65 PolarHBondContact O-N 2.93Å; S62-H125 WeakPolarHBondContact CB-NE2 2.94Å; S62-L140 WeakPolarHBondContact CB-O 3.41Å; S62-L140 VanDerWaalsContact OG-C 3.32Å; S62-L140 PolarHBondContact OG-O 2.8Å; S62-K141 PolarHBondContact OG-O 3.04Å; S62-K142 WeakPolarHBondContact OG-CA 3.37Å; S62-K142 PolarHBondContact OG-N 3.41Å; S62-K142 VanDerWaalsContact OG-N 3.08Å; S62-A145 WeakPolarHBondContact O-CB 2.91Å
63	I	84.3	Confident	88.7	Confident	16 Å²	16	39 Å²	39	8%	0.082	21%	0.205	C	C	.	.	H	α-helix	trans	-67.1	-33.2	174.6	-168.8	171.6	0	0	0	112.7	S61 V65 Y66 M67 I122 H125 R126	S61-I63 VanDerWaalsContact C-N 3.34Å; S61-I63 PolarHBondContact O-N 3.04Å; S61-I63 VanDerWaalsContact OG-CG2 3.29Å; S61-I63 WeakPolarHBondContact OG-CG2 3.43Å; I63-V65 PolarHBondContact O-N 3.43Å; I63-Y66 PolarHBondContact O-N 3.09Å; I63-M67 HydrophobicContact CD1-CE 3.81Å; I63-M67 HydrophobicContact CG1-CE 3.93Å; I63-M67 HydrophobicContact CG1-CG 4.42Å; I63-M67 HydrophobicContact CG1-SD 4.21Å; I63-M67 WeakPolarHBondContact O-CG 3.37Å; I63-M67 PolarHBondContact O-N 3.41Å; I63-I122 HydrophobicContact CD1-CG2 4.1Å; I63-I122 HydrophobicContact CG1-CG1 4.41Å; I63-I122 HydrophobicContact CG1-CG2 4.43Å; I63-H125 PolarHBondContact N-NE2 2.98Å; I63-R126 HydrophobicContact CD1-CG 4.29Å; I63-R126 VanDerWaalsContact CD1-NH2 3.34Å
64	S	87.2	Confident	89	Confident	8 Å²	8	38.9 Å²	38.9	6%	0.056	21%	0.205	C	C	.	.	H	α-helix	trans	-63.6	-30.1	175	-55.4	0	0	0	0	112.1	S61 S62 F68	S61-S64 WeakPolarHBondContact O-CB 3.21Å; S61-S64 PolarHBondContact O-N 3.46Å; S61-S64 VanDerWaalsContact O-N 3.07Å; S61-S64 PolarHBondContact OG-N 2.97Å; S61-S64 PolarHBondContact OG-OG 3.11Å; S62-S64 VanDerWaalsContact C-N 3.33Å; S62-S64 PolarHBondContact O-N 2.8Å; S64-F68 VanDerWaalsContact O-CB 3.28Å; S64-F68 WeakPolarHBondContact O-CB 3.43Å; S64-F68 PolarHBondContact O-N 2.87Å
65	V	92.4	Very high	89.3	Confident	5 Å²	5	38.5 Å²	38.5	3%	0.03	20%	0.198	C	C	.	.	H	α-helix	trans	-63.5	-47.9	173.8	-180	0	0	0	0	110.4	W60 S61 S62 I63 F68 N69 K142 A145 V146	W60-V65 HydrophobicContact CE3-CG2 4.21Å; S61-V65 PolarHBondContact O-N 3.46Å; S62-V65 WeakPolarHBondContact O-CB 3.29Å; S62-V65 PolarHBondContact O-N 2.93Å; I63-V65 PolarHBondContact O-N 3.43Å; V65-F68 PolarHBondContact O-N 3.3Å; V65-N69 PolarHBondContact O-N 3.23Å; V65-N69 VanDerWaalsContact O-N 3.14Å; V65-N69 PolarHBondContact O-ND2 2.78Å; V65-K142 HydrophobicContact CG2-CG 4.16Å; V65-A145 HydrophobicContact CB-CB 4.06Å; V65-A145 HydrophobicContact CG1-CB 4.34Å; V65-A145 HydrophobicContact CG2-CB 4.29Å; V65-V146 HydrophobicContact CG1-CG2 4.08Å; V65-V146 HydrophobicContact CG2-CG2 4.25Å
66	Y	92.5	Very high	89.8	Confident	21 Å²	21	37.8 Å²	37.8	8%	0.082	19%	0.194	C	C	.	.	H	α-helix	trans	-65.1	-44	178.8	-57.8	-43.1	0	0	0	112.2	I63 F68 N69 L70 F118 C121 I122 H125 A145 T148 S149	I63-Y66 PolarHBondContact O-N 3.09Å; Y66-F68 VanDerWaalsContact C-N 3.32Å; Y66-F68 PolarHBondContact O-N 2.9Å; Y66-N69 PolarHBondContact O-N 3.47Å; Y66-L70 PolarHBondContact O-N 3.39Å; Y66-F118 HydrophobicContact CD1-CD1 4.25Å; Y66-C121 HydrophobicContact CD1-CB 4.01Å; Y66-C121 HydrophobicContact CD2-CB 4.01Å; Y66-C121 HydrophobicContact CE1-CB 4Å; Y66-C121 HydrophobicContact CE2-CB 3.98Å; Y66-C121 HydrophobicContact CG-CB 4.02Å; Y66-I122 HydrophobicContact CD2-CG1 4.36Å; Y66-I122 HydrophobicContact CG-CG1 4.45Å; Y66-H125 HydrophobicContact CE2-CB 4.25Å; Y66-A145 HydrophobicContact CE1-CB 3.95Å; Y66-A145 WeakPolarHBondContact CE1-O 3.17Å; Y66-A145 HydrophobicContact CE2-CB 4.28Å; Y66-A145 WeakPolarHBondContact OH-CA 3.44Å; Y66-T148 HydrophobicContact CE1-CG2 4.11Å; Y66-S149 WeakPolarHBondContact CD1-OG 3.38Å
67	M	90.8	Very high	90.5	Very high	15 Å²	15	34.9 Å²	34.9	7%	0.074	18%	0.18	C	C	.	.	H	α-helix	trans	-62.5	-37.7	177.2	-70.5	173.9	166.5	0	0	112.6	F53 I63 L70 A71 I122 Y300 A303	F53-M67 HydrophobicContact CE1-CB 4.29Å; F53-M67 HydrophobicContact CE2-CB 4.16Å; F53-M67 HydrophobicContact CZ-CB 3.55Å; I63-M67 HydrophobicContact CD1-CE 3.81Å; I63-M67 HydrophobicContact CG1-CE 3.93Å; I63-M67 HydrophobicContact CG1-CG 4.42Å; I63-M67 HydrophobicContact CG1-SD 4.21Å; I63-M67 WeakPolarHBondContact O-CG 3.37Å; I63-M67 PolarHBondContact O-N 3.41Å; M67-L70 PolarHBondContact O-N 3.46Å; M67-A71 WeakPolarHBondContact O-CB 3.21Å; M67-A71 PolarHBondContact O-N 3.22Å; M67-I122 HydrophobicContact CG-CD1 4.05Å; M67-Y300 HydrophobicContact CB-CD1 3.82Å; M67-Y300 HydrophobicContact CB-CE1 3.72Å; M67-Y300 HydrophobicContact CG-CD1 3.9Å; M67-Y300 HydrophobicContact CG-CE1 3.97Å; M67-Y300 PolarHBondContact O-OH 3.29Å; M67-Y300 HydrophobicContact SD-CD1 4.18Å; M67-A303 HydrophobicContact CE-CB 4.24Å
68	F	93.3	Very high	91.3	Very high	37 Å²	37	33.9 Å²	33.9	16%	0.162	18%	0.175	C	C	.	.	H	α-helix	trans	-64.2	-43.2	175	175.6	-97.8	0	0	0	112	I50 F53 V54 W60 S64 V65 Y66 L70 A71 L72	I50-F68 HydrophobicContact CG1-CE2 4.47Å; I50-F68 HydrophobicContact CG2-CE2 4.17Å; F53-F68 HydrophobicContact CB-CD2 3.65Å; F53-F68 HydrophobicContact CB-CE2 4.37Å; F53-F68 HydrophobicContact CD2-CB 4.16Å; F53-F68 HydrophobicContact CD2-CD2 4.05Å; F53-F68 HydrophobicContact CG-CB 4.21Å; F53-F68 HydrophobicContact CG-CD2 4.06Å; V54-F68 HydrophobicContact CG2-CE2 3.97Å; W60-F68 HydrophobicContact CH2-CB 4.01Å; W60-F68 AromaticContact CH2-CD1 3.62Å; W60-F68 HydrophobicContact CH2-CD1 3.62Å; W60-F68 AromaticContact CH2-CD2 3.53Å; W60-F68 HydrophobicContact CH2-CD2 3.53Å; W60-F68 AromaticContact CH2-CE1 3.92Å; W60-F68 HydrophobicContact CH2-CE1 3.92Å; W60-F68 AromaticContact CH2-CE2 3.82Å; W60-F68 HydrophobicContact CH2-CE2 3.82Å; W60-F68 AromaticContact CH2-CG 3.41Å; W60-F68 HydrophobicContact CH2-CG 3.41Å; W60-F68 VanDerWaalsContact CH2-CG 3.41Å; W60-F68 HydrophobicContact CH2-CZ 4.01Å; W60-F68 HydrophobicContact CZ2-CD2 4.17Å; W60-F68 HydrophobicContact CZ2-CE2 4.43Å; W60-F68 HydrophobicContact CZ2-CG 4.39Å; W60-F68 HydrophobicContact CZ3-CB 3.85Å; W60-F68 AromaticContact CZ3-CD1 3.7Å; W60-F68 HydrophobicContact CZ3-CD1 3.7Å; W60-F68 HydrophobicContact CZ3-CD2 4.23Å; W60-F68 HydrophobicContact CZ3-CE1 4.32Å; W60-F68 AromaticContact CZ3-CG 3.64Å; W60-F68 HydrophobicContact CZ3-CG 3.64Å; S64-F68 VanDerWaalsContact O-CB 3.28Å; S64-F68 WeakPolarHBondContact O-CB 3.43Å; S64-F68 PolarHBondContact O-N 2.87Å; V65-F68 PolarHBondContact O-N 3.3Å; Y66-F68 VanDerWaalsContact C-N 3.32Å; Y66-F68 PolarHBondContact O-N 2.9Å; F68-L70 VanDerWaalsContact C-N 3.34Å; F68-A71 PolarHBondContact O-N 3.18Å; F68-L72 WeakPolarHBondContact O-CB 3.43Å; F68-L72 PolarHBondContact O-N 3.15Å
69	N	95.9	Very high	92.1	Very high	21 Å²	21	29.5 Å²	29.5	11%	0.112	16%	0.164	C	C	.	.	H	α-helix	trans	-67.6	-35.6	178	-77.1	-85.1	0	0	0	112.3	V65 Y66 L72 A73 F118 W153	V65-N69 PolarHBondContact O-N 3.23Å; V65-N69 VanDerWaalsContact O-N 3.14Å; V65-N69 PolarHBondContact O-ND2 2.78Å; Y66-N69 PolarHBondContact O-N 3.47Å; N69-L72 PolarHBondContact O-N 3.37Å; N69-A73 PolarHBondContact O-N 3.08Å; N69-F118 HydrophobicContact CB-CD1 4.07Å; N69-F118 HydrophobicContact CB-CD2 4.22Å; N69-F118 HydrophobicContact CB-CE1 3.51Å; N69-F118 HydrophobicContact CB-CE2 3.69Å; N69-F118 HydrophobicContact CB-CG 4.42Å; N69-F118 HydrophobicContact CB-CZ 3.33Å; N69-W153 PolarHBondContact OD1-NE1 3.29Å
70	L	93.9	Very high	92.8	Very high	0 Å²	0	23.9 Å²	23.9	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-60.4	-51.8	172	-174.4	64.2	0	0	0	110.7	Y66 M67 F68 L72 A73 D74 S115 F118 L119 I122 D296 Y300	Y66-L70 PolarHBondContact O-N 3.39Å; M67-L70 PolarHBondContact O-N 3.46Å; F68-L70 VanDerWaalsContact C-N 3.34Å; L70-L72 VanDerWaalsContact C-N 3.25Å; L70-L72 PolarHBondContact O-N 3.01Å; L70-A73 WeakPolarHBondContact O-CB 3.49Å; L70-A73 PolarHBondContact O-N 3.28Å; L70-A73 VanDerWaalsContact O-N 3.08Å; L70-D74 PolarHBondContact O-N 2.88Å; L70-S115 VanDerWaalsContact CD1-CA 3.42Å; L70-S115 VanDerWaalsContact CD1-OG 3.31Å; L70-S115 WeakPolarHBondContact CD1-OG 3.47Å; L70-F118 HydrophobicContact CB-CB 4.28Å; L70-F118 HydrophobicContact CD1-CB 4.2Å; L70-L119 HydrophobicContact CD2-CD2 3.99Å; L70-L119 HydrophobicContact CD2-CG 4.42Å; L70-I122 HydrophobicContact CD2-CD1 4.36Å; L70-D296 HydrophobicContact CD2-CB 4.16Å; L70-D296 HydrophobicContact CG-CB 4.38Å; L70-Y300 WeakPolarHBondContact CB-OH 3.46Å; L70-Y300 HydrophobicContact CD2-CE1 4.17Å; L70-Y300 WeakPolarHBondContact CD2-OH 3.48Å; L70-Y300 WeakPolarHBondContact CG-OH 3.43Å
71	A	94.5	Very high	93.4	Very high	0 Å²	0	21.6 Å²	21.6	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-59.2	-35.9	176.9	0	0	0	0	0	112.7	A49 I50 M67 F68 F75 Y300	A49-A71 HydrophobicContact CB-CB 4.24Å; I50-A71 HydrophobicContact CG1-CB 4.11Å; M67-A71 WeakPolarHBondContact O-CB 3.21Å; M67-A71 PolarHBondContact O-N 3.22Å; F68-A71 PolarHBondContact O-N 3.18Å; A71-F75 WeakPolarHBondContact O-CB 3.42Å; A71-F75 PolarHBondContact O-N 2.87Å; A71-Y300 WeakPolarHBondContact CA-OH 3.44Å; A71-Y300 HydrophobicContact CB-CE2 3.85Å; A71-Y300 PolarHBondContact N-OH 3.21Å
72	L	96.2	Very high	94.1	Very high	60 Å²	60	21.6 Å²	21.6	31%	0.314	12%	0.118	S	C	.	.	H	α-helix	trans	-66.9	-44.3	175.2	-176.2	63.9	0	0	0	111.8	F68 N69 L70 D74 F75 C76	F68-L72 WeakPolarHBondContact O-CB 3.43Å; F68-L72 PolarHBondContact O-N 3.15Å; N69-L72 PolarHBondContact O-N 3.37Å; L70-L72 VanDerWaalsContact C-N 3.25Å; L70-L72 PolarHBondContact O-N 3.01Å; L72-D74 VanDerWaalsContact C-N 3.35Å; L72-F75 PolarHBondContact O-N 3Å; L72-C76 PolarHBondContact O-N 3.35Å; L72-C76 PolarHBondContact O-SG 3.35Å
73	A	96.4	Very high	94.6	Very high	3 Å²	3	24.5 Å²	24.5	3%	0.025	13%	0.13	C	C	.	.	H	α-helix	trans	-61.9	-42.9	176.9	0	0	0	0	0	111.7	N69 L70 Y77 N111 W153	N69-A73 PolarHBondContact O-N 3.08Å; L70-A73 WeakPolarHBondContact O-CB 3.49Å; L70-A73 PolarHBondContact O-N 3.28Å; L70-A73 VanDerWaalsContact O-N 3.08Å; A73-Y77 PolarHBondContact O-N 3.01Å; A73-Y77 VanDerWaalsContact O-N 3.15Å; A73-N111 VanDerWaalsContact C-ND2 3.26Å; A73-N111 PolarHBondContact O-ND2 3.04Å; A73-N111 VanDerWaalsContact O-ND2 3.08Å; A73-W153 HydrophobicContact CB-CH2 3.75Å; A73-W153 HydrophobicContact CB-CZ2 4.17Å
74	D	96.1	Very high	95.1	Very high	0 Å²	0	24 Å²	24	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-66.1	-43.9	176.4	-70.5	-40.6	0	0	0	112.3	L70 L72 C76 Y77 V78 N111 S293 D296	L70-D74 PolarHBondContact O-N 2.88Å; L72-D74 VanDerWaalsContact C-N 3.35Å; D74-C76 PolarHBondContact O-N 2.94Å; D74-Y77 PolarHBondContact O-N 2.88Å; D74-V78 WeakPolarHBondContact O-CB 3.36Å; D74-V78 VanDerWaalsContact O-CG2 3.23Å; D74-V78 WeakPolarHBondContact O-CG2 3.35Å; D74-V78 PolarHBondContact O-N 3.41Å; D74-N111 VanDerWaalsContact CA-ND2 3.31Å; D74-N111 WeakPolarHBondContact CA-ND2 3.48Å; D74-N111 PolarHBondContact N-ND2 3.1Å; D74-N111 PolarHBondContact OD1-ND2 3.06Å; D74-S293 WeakPolarHBondContact OD1-CA 3.43Å; D74-S293 WeakPolarHBondContact OD1-CB 3.47Å; D74-S293 PolarHBondContact OD1-OG 2.64Å; D74-D296 WeakPolarHBondContact OD2-CB 3.35Å; D74-D296 VanDerWaalsContact OD2-OD2 3.08Å
75	F	96.2	Very high	95.6	Very high	51 Å²	51	24.5 Å²	24.5	22%	0.224	13%	0.129	C	C	.	.	H	α-helix	trans	-59.9	-45.9	177.5	-177.7	-105.2	0	0	0	111.8	L43 N46 S47 I50 A71 L72 Y77 V78 L79	L43-F75 HydrophobicContact CD1-CD2 4.35Å; L43-F75 HydrophobicContact CD1-CE2 3.71Å; N46-F75 HydrophobicContact CB-CB 4.12Å; S47-F75 WeakPolarHBondContact OG-CE2 3.06Å; I50-F75 HydrophobicContact CD1-CB 3.72Å; I50-F75 HydrophobicContact CD1-CD1 4.2Å; I50-F75 HydrophobicContact CD1-CD2 4.42Å; I50-F75 HydrophobicContact CD1-CG 3.87Å; A71-F75 WeakPolarHBondContact O-CB 3.42Å; A71-F75 PolarHBondContact O-N 2.87Å; L72-F75 PolarHBondContact O-N 3Å; F75-Y77 VanDerWaalsContact C-N 3.33Å; F75-Y77 PolarHBondContact O-N 3.17Å; F75-V78 PolarHBondContact O-N 2.92Å; F75-L79 HydrophobicContact CD1-CD1 3.94Å; F75-L79 HydrophobicContact CD1-CG 4.49Å; F75-L79 HydrophobicContact CE1-CD1 3.43Å; F75-L79 VanDerWaalsContact CE1-CD1 3.43Å; F75-L79 HydrophobicContact CE1-CG 4.16Å; F75-L79 HydrophobicContact CE2-CD1 4.5Å; F75-L79 HydrophobicContact CE2-CD2 4.49Å; F75-L79 HydrophobicContact CE2-CG 4.42Å; F75-L79 HydrophobicContact CZ-CD1 3.75Å; F75-L79 HydrophobicContact CZ-CD2 4.24Å; F75-L79 HydrophobicContact CZ-CG 4.12Å; F75-L79 WeakPolarHBondContact O-CG 3.48Å; F75-L79 PolarHBondContact O-N 2.63Å
76	C	96.8	Very high	95.8	Very high	60 Å²	60	28.5 Å²	28.5	41%	0.405	15%	0.147	S	C	.	.	H	α-helix	trans	-60.2	-40.7	175.9	-70.9	0	0	0	0	112.5	L72 D74	L72-C76 PolarHBondContact O-N 3.35Å; L72-C76 PolarHBondContact O-SG 3.35Å; D74-C76 PolarHBondContact O-N 2.94Å
77	Y	97.5	Very high	95.9	Very high	0 Å²	0	28 Å²	28	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-67.2	-47.3	176.5	168.7	-119.8	0	0	0	112.5	A73 D74 F75 L79 S80 L81 I107 F108 N111 S290 S293	A73-Y77 PolarHBondContact O-N 3.01Å; A73-Y77 VanDerWaalsContact O-N 3.15Å; D74-Y77 PolarHBondContact O-N 2.88Å; F75-Y77 VanDerWaalsContact C-N 3.33Å; F75-Y77 PolarHBondContact O-N 3.17Å; Y77-L79 VanDerWaalsContact C-N 3.27Å; Y77-L79 PolarHBondContact O-N 3.43Å; Y77-S80 WeakPolarHBondContact O-CA 3.39Å; Y77-S80 WeakPolarHBondContact O-CB 3.49Å; Y77-S80 PolarHBondContact O-N 3.28Å; Y77-S80 PolarHBondContact O-OG 2.96Å; Y77-L81 HydrophobicContact CE1-CD1 4.49Å; Y77-L81 HydrophobicContact CE1-CD2 4.12Å; Y77-L81 HydrophobicContact CE2-CD2 3.82Å; Y77-L81 PolarHBondContact O-N 3.29Å; Y77-L81 WeakPolarHBondContact OH-CD2 3.45Å; Y77-I107 HydrophobicContact CD2-CG2 4.45Å; Y77-F108 HydrophobicContact CD2-CB 4.42Å; Y77-F108 HydrophobicContact CD2-CD2 4.41Å; Y77-F108 HydrophobicContact CE2-CB 4.13Å; Y77-F108 AromaticContact CE2-CD2 3.61Å; Y77-F108 HydrophobicContact CE2-CD2 3.61Å; Y77-F108 HydrophobicContact CE2-CG 4.36Å; Y77-F108 AromaticContact CZ-CD2 3.82Å; Y77-N111 HydrophobicContact CG-CB 4.1Å; Y77-S290 WeakPolarHBondContact OH-CB 3.3Å; Y77-S293 WeakPolarHBondContact CD1-OG 3.42Å
78	V	97.3	Very high	96	Very high	0 Å²	0	27.6 Å²	27.6	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-56.5	-42.4	178.4	164.1	0	0	0	0	111	V38 F39 L43 D74 F75 S80 L81	V38-V78 HydrophobicContact CG1-CG2 4.49Å; F39-V78 HydrophobicContact CD2-CG1 3.89Å; F39-V78 WeakPolarHBondContact CD2-O 3.42Å; F39-V78 HydrophobicContact CE2-CG1 4.43Å; L43-V78 HydrophobicContact CB-CG1 3.88Å; L43-V78 HydrophobicContact CD1-CG1 4.38Å; D74-V78 WeakPolarHBondContact O-CB 3.36Å; D74-V78 VanDerWaalsContact O-CG2 3.23Å; D74-V78 WeakPolarHBondContact O-CG2 3.35Å; D74-V78 PolarHBondContact O-N 3.41Å; F75-V78 PolarHBondContact O-N 2.92Å; V78-S80 PolarHBondContact O-N 3.3Å; V78-L81 HydrophobicContact CG2-CD1 4.4Å; V78-L81 WeakPolarHBondContact O-CB 3.34Å; V78-L81 PolarHBondContact O-N 3.02Å
79	L	97.1	Very high	96.1	Very high	85 Å²	85	31.5 Å²	31.5	45%	0.445	16%	0.159	S	C	.	.	H	α-helix	trans	-61	-23.8	175.7	-74.1	179.9	0	0	0	113.9	L43 F75 Y77 P82	L43-L79 HydrophobicContact CD1-CD2 3.95Å; F75-L79 HydrophobicContact CD1-CD1 3.94Å; F75-L79 HydrophobicContact CD1-CG 4.49Å; F75-L79 HydrophobicContact CE1-CD1 3.43Å; F75-L79 VanDerWaalsContact CE1-CD1 3.43Å; F75-L79 HydrophobicContact CE1-CG 4.16Å; F75-L79 HydrophobicContact CE2-CD1 4.5Å; F75-L79 HydrophobicContact CE2-CD2 4.49Å; F75-L79 HydrophobicContact CE2-CG 4.42Å; F75-L79 HydrophobicContact CZ-CD1 3.75Å; F75-L79 HydrophobicContact CZ-CD2 4.24Å; F75-L79 HydrophobicContact CZ-CG 4.12Å; F75-L79 WeakPolarHBondContact O-CG 3.48Å; F75-L79 PolarHBondContact O-N 2.63Å; Y77-L79 VanDerWaalsContact C-N 3.27Å; Y77-L79 PolarHBondContact O-N 3.43Å; L79-P82 WeakPolarHBondContact O-CD 3.47Å
80	S	96.8	Very high	96	Very high	7 Å²	7	33.2 Å²	33.2	5%	0.049	17%	0.169	C	C	.	.	H	α-helix	trans	-83.3	-19.5	176	78.9	0	0	0	0	113.6	Y77 V78 F83 Q104	Y77-S80 WeakPolarHBondContact O-CA 3.39Å; Y77-S80 WeakPolarHBondContact O-CB 3.49Å; Y77-S80 PolarHBondContact O-N 3.28Å; Y77-S80 PolarHBondContact O-OG 2.96Å; V78-S80 PolarHBondContact O-N 3.3Å; S80-F83 WeakPolarHBondContact O-CD2 3.26Å; S80-F83 PolarHBondContact O-N 3.41Å; S80-Q104 PolarHBondContact O-OE1 3.11Å; S80-Q104 PolarHBondContact OG-NE2 2.74Å
81	L	97.1	Very high	95.8	Very high	0 Å²	0	38.2 Å²	38.2	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-56.3	-34.4	-175.6	-69.8	176.5	0	0	0	115.7	Y35 V38 F39 Y77 V78 F83 L84 I85	Y35-L81 HydrophobicContact CD1-CD2 3.97Å; Y35-L81 HydrophobicContact CG-CD2 4.19Å; V38-L81 HydrophobicContact CB-CD1 3.93Å; V38-L81 HydrophobicContact CG1-CD1 3.47Å; V38-L81 VanDerWaalsContact CG1-CD1 3.47Å; F39-L81 HydrophobicContact CB-CB 4.32Å; F39-L81 HydrophobicContact CB-CD1 4.14Å; F39-L81 HydrophobicContact CD2-CB 4.4Å; Y77-L81 HydrophobicContact CE1-CD1 4.49Å; Y77-L81 HydrophobicContact CE1-CD2 4.12Å; Y77-L81 HydrophobicContact CE2-CD2 3.82Å; Y77-L81 PolarHBondContact O-N 3.29Å; Y77-L81 WeakPolarHBondContact OH-CD2 3.45Å; V78-L81 HydrophobicContact CG2-CD1 4.4Å; V78-L81 WeakPolarHBondContact O-CB 3.34Å; V78-L81 PolarHBondContact O-N 3.02Å; L81-F83 PolarHBondContact O-N 2.92Å; L81-L84 PolarHBondContact O-N 3.24Å; L81-I85 HydrophobicContact CB-CD1 4.29Å; L81-I85 WeakPolarHBondContact O-CG1 3.41Å; L81-I85 PolarHBondContact O-N 3.39Å
82	P	97.6	Very high	95.6	Very high	56 Å²	56	38.5 Å²	38.5	36%	0.364	19%	0.192	S	C	.	.	H	α-helix	trans	-53.3	-37.6	176.9	-30	37.9	0	0	0	114.1	F39 L79 L84 I85 F86	F39-P82 HydrophobicContact CD2-CG 4.1Å; F39-P82 HydrophobicContact CE2-CG 3.75Å; F39-P82 HydrophobicContact CZ-CG 4.14Å; L79-P82 WeakPolarHBondContact O-CD 3.47Å; P82-L84 VanDerWaalsContact C-N 3.33Å; P82-L84 PolarHBondContact O-N 3.41Å; P82-I85 PolarHBondContact O-N 2.99Å; P82-F86 WeakPolarHBondContact O-CB 3.34Å; P82-F86 PolarHBondContact O-N 3.4Å
83	F	96.5	Very high	95.4	Very high	69 Å²	69	37.3 Å²	37.3	30%	0.303	19%	0.186	S	C	.	.	H	α-helix	trans	-63.6	-40.7	176.4	-62.2	-73.5	0	0	0	111.7	S80 L81 Y87 W94 F96 L100	S80-F83 WeakPolarHBondContact O-CD2 3.26Å; S80-F83 PolarHBondContact O-N 3.41Å; L81-F83 PolarHBondContact O-N 2.92Å; F83-Y87 VanDerWaalsContact O-CB 3.28Å; F83-Y87 WeakPolarHBondContact O-CB 3.45Å; F83-Y87 PolarHBondContact O-N 3.47Å; F83-W94 HydrophobicContact CB-CH2 3.9Å; F83-W94 HydrophobicContact CB-CZ3 4.3Å; F83-F96 HydrophobicContact CB-CD2 4.39Å; F83-F96 HydrophobicContact CB-CE2 4.26Å; F83-F96 AromaticContact CD1-CD1 3.91Å; F83-F96 HydrophobicContact CD1-CD1 3.91Å; F83-F96 AromaticContact CD1-CD2 3.92Å; F83-F96 HydrophobicContact CD1-CD2 3.92Å; F83-F96 AromaticContact CD1-CE1 3.98Å; F83-F96 HydrophobicContact CD1-CE1 3.98Å; F83-F96 AromaticContact CD1-CE2 3.99Å; F83-F96 HydrophobicContact CD1-CE2 3.99Å; F83-F96 AromaticContact CD1-CG 3.88Å; F83-F96 HydrophobicContact CD1-CG 3.88Å; F83-F96 HydrophobicContact CD1-CZ 4.02Å; F83-F96 HydrophobicContact CE1-CD1 4.15Å; F83-F96 HydrophobicContact CE1-CE1 4.34Å; F83-F96 HydrophobicContact CE1-CG 4.42Å; F83-L100 HydrophobicContact CE1-CD1 4.18Å
84	L	95.4	Very high	95.3	Very high	6 Å²	6	37.4 Å²	37.4	3%	0.031	19%	0.186	C	C	.	.	H	α-helix	trans	-73.5	-39.6	-179.7	-161	62.1	0	0	0	111.6	Y35 L81 P82 Y87 Y88	Y35-L84 HydrophobicContact CD2-CB 4.37Å; Y35-L84 HydrophobicContact CD2-CD2 3.82Å; Y35-L84 HydrophobicContact CD2-CG 3.93Å; Y35-L84 HydrophobicContact CE1-CD2 4.14Å; Y35-L84 HydrophobicContact CE2-CB 4.46Å; Y35-L84 HydrophobicContact CE2-CD2 3.23Å; Y35-L84 HydrophobicContact CE2-CG 3.56Å; Y35-L84 HydrophobicContact CG-CD2 4.49Å; Y35-L84 VanDerWaalsContact CZ-CD2 3.4Å; L81-L84 PolarHBondContact O-N 3.24Å; P82-L84 VanDerWaalsContact C-N 3.33Å; P82-L84 PolarHBondContact O-N 3.41Å; L84-Y87 HydrophobicContact CD1-CD1 4.05Å; L84-Y87 WeakPolarHBondContact O-CB 3.21Å; L84-Y87 PolarHBondContact O-N 3.37Å; L84-Y88 HydrophobicContact CD1-CD2 4.3Å; L84-Y88 HydrophobicContact CD1-CE2 3.79Å; L84-Y88 HydrophobicContact CG-CD2 4.07Å; L84-Y88 HydrophobicContact CG-CE2 3.84Å; L84-Y88 WeakPolarHBondContact O-CD2 3.34Å; L84-Y88 PolarHBondContact O-N 2.93Å; L84-Y88 VanDerWaalsContact O-N 3.08Å
85	I	97	Very high	95.3	Very high	19 Å²	19	42 Å²	42	10%	0.097	21%	0.209	C	C	.	.	H	α-helix	trans	-57.5	-52.5	173.3	-68	162.3	0	0	0	109.8	I36 F39 L81 P82 Y87 Y88 F89	I36-I85 HydrophobicContact CD1-CG2 4.19Å; I36-I85 HydrophobicContact CG1-CD1 3.83Å; I36-I85 HydrophobicContact CG1-CG1 4.16Å; I36-I85 HydrophobicContact CG1-CG2 3.91Å; F39-I85 HydrophobicContact CB-CD1 4.27Å; L81-I85 HydrophobicContact CB-CD1 4.29Å; L81-I85 WeakPolarHBondContact O-CG1 3.41Å; L81-I85 PolarHBondContact O-N 3.39Å; P82-I85 PolarHBondContact O-N 2.99Å; I85-Y87 VanDerWaalsContact C-N 3.35Å; I85-Y87 PolarHBondContact O-N 3.45Å; I85-Y88 PolarHBondContact O-N 2.94Å; I85-F89 HydrophobicContact CG2-CD2 3.67Å; I85-F89 HydrophobicContact CG2-CE2 3.5Å; I85-F89 VanDerWaalsContact CG2-CE2 3.5Å; I85-F89 WeakPolarHBondContact O-CD2 3.33Å; I85-F89 PolarHBondContact O-N 3.42Å
86	F	96.8	Very high	95.2	Very high	89 Å²	89	42.5 Å²	42.5	39%	0.39	21%	0.211	S	C	.	.	H	α-helix	trans	-59.3	-45.7	177.9	-176.4	-85.3	0	0	0	111.7	P82 Y88 F89 N90 I95 F96	P82-F86 WeakPolarHBondContact O-CB 3.34Å; P82-F86 PolarHBondContact O-N 3.4Å; F86-Y88 VanDerWaalsContact C-N 3.29Å; F86-Y88 PolarHBondContact O-N 3Å; F86-F89 PolarHBondContact O-N 3.21Å; F86-N90 HydrophobicContact CD1-CB 4.26Å; F86-N90 HydrophobicContact CE1-CB 3.93Å; F86-N90 HydrophobicContact CZ-CB 4.5Å; F86-N90 VanDerWaalsContact O-CB 3.27Å; F86-N90 WeakPolarHBondContact O-CB 3.43Å; F86-N90 PolarHBondContact O-N 3.35Å; F86-I95 HydrophobicContact CD1-CD1 4.38Å; F86-I95 HydrophobicContact CD1-CG1 4.46Å; F86-I95 HydrophobicContact CE1-CD1 3.4Å; F86-I95 VanDerWaalsContact CE1-CD1 3.4Å; F86-I95 HydrophobicContact CE1-CG1 3.81Å; F86-I95 HydrophobicContact CZ-CD1 3.73Å; F86-F96 HydrophobicContact CB-CE2 4.25Å; F86-F96 HydrophobicContact CB-CZ 4Å; F86-F96 AromaticContact CD1-CE2 3.69Å; F86-F96 HydrophobicContact CD1-CE2 3.69Å; F86-F96 AromaticContact CD1-CZ 3.45Å; F86-F96 HydrophobicContact CD1-CZ 3.45Å; F86-F96 VanDerWaalsContact CD1-CZ 3.45Å; F86-F96 HydrophobicContact CE1-CE2 4.49Å; F86-F96 HydrophobicContact CE1-CZ 4.12Å; F86-F96 HydrophobicContact CG-CE2 4.26Å; F86-F96 AromaticContact CG-CZ 3.79Å; F86-F96 HydrophobicContact CG-CZ 3.79Å
87	Y	94.9	Very high	95.1	Very high	9 Å²	9	41.4 Å²	41.4	4%	0.035	21%	0.211	C	C	.	.	H	α-helix	trans	-54.7	-42.9	178.2	167.6	-109.3	0	0	0	112.9	F83 L84 I85 N90 T92 W94 C178	F83-Y87 VanDerWaalsContact O-CB 3.28Å; F83-Y87 WeakPolarHBondContact O-CB 3.45Å; F83-Y87 PolarHBondContact O-N 3.47Å; L84-Y87 HydrophobicContact CD1-CD1 4.05Å; L84-Y87 WeakPolarHBondContact O-CB 3.21Å; L84-Y87 PolarHBondContact O-N 3.37Å; I85-Y87 VanDerWaalsContact C-N 3.35Å; I85-Y87 PolarHBondContact O-N 3.45Å; Y87-N90 CarbonylContact O-C 3.56Å; Y87-T92 HydrophobicContact CD1-CG2 4.33Å; Y87-T92 HydrophobicContact CE1-CG2 3.66Å; Y87-T92 VanDerWaalsContact CE2-CA 3.41Å; Y87-T92 HydrophobicContact CE2-CG2 4.43Å; Y87-T92 WeakPolarHBondContact CE2-O 3.46Å; Y87-T92 WeakPolarHBondContact O-CA 3.42Å; Y87-T92 PolarHBondContact O-N 2.62Å; Y87-T92 WeakPolarHBondContact OH-CB 3.25Å; Y87-W94 HydrophobicContact CD2-CB 3.83Å; Y87-W94 HydrophobicContact CD2-CD2 4.48Å; Y87-W94 AromaticContact CD2-CE3 3.74Å; Y87-W94 HydrophobicContact CD2-CE3 3.74Å; Y87-W94 HydrophobicContact CE2-CB 3.88Å; Y87-W94 HydrophobicContact CE2-CE3 4.41Å; Y87-W94 AromaticContact CG-CE3 3.88Å; Y87-W94 HydrophobicContact CG-CE3 3.88Å; Y87-W94 HydrophobicContact CG-CZ3 4.44Å; Y87-C178 HydrophobicContact CE2-CB 4.49Å
88	Y	93.8	Very high	95	Very high	8 Å²	8	43.7 Å²	43.7	3%	0.031	22%	0.223	C	C	.	.	H	α-helix	trans	-74.9	-36.7	179.1	-83.2	-71.2	0	0	0	113.3	F28 L31 P32 Y35 L84 I85 F86 N90 K91 T92 R286	F28-Y88 HydrophobicContact CD1-CD1 4.37Å; L31-Y88 HydrophobicContact CB-CD1 4.26Å; L31-Y88 HydrophobicContact CB-CD2 4.04Å; L31-Y88 HydrophobicContact CB-CE1 4.32Å; L31-Y88 HydrophobicContact CB-CE2 4.13Å; L31-Y88 HydrophobicContact CB-CG 4.16Å; L31-Y88 HydrophobicContact CD1-CD1 4.13Å; L31-Y88 HydrophobicContact CD1-CD2 4.47Å; L31-Y88 HydrophobicContact CD1-CE1 3.4Å; L31-Y88 HydrophobicContact CD1-CE2 3.83Å; L31-Y88 VanDerWaalsContact CD1-OH 3.32Å; L31-Y88 WeakPolarHBondContact CD1-OH 3.47Å; L31-Y88 HydrophobicContact CG-CE1 4.47Å; P32-Y88 HydrophobicContact CG-CG 4.3Å; Y35-Y88 HydrophobicContact CD2-CD2 4.3Å; Y35-Y88 AromaticContact CE2-CD2 3.91Å; Y35-Y88 HydrophobicContact CE2-CD2 3.91Å; Y35-Y88 AromaticContact CE2-CE2 3.74Å; Y35-Y88 HydrophobicContact CE2-CE2 3.74Å; L84-Y88 HydrophobicContact CD1-CD2 4.3Å; L84-Y88 HydrophobicContact CD1-CE2 3.79Å; L84-Y88 HydrophobicContact CG-CD2 4.07Å; L84-Y88 HydrophobicContact CG-CE2 3.84Å; L84-Y88 WeakPolarHBondContact O-CD2 3.34Å; L84-Y88 PolarHBondContact O-N 2.93Å; L84-Y88 VanDerWaalsContact O-N 3.08Å; I85-Y88 PolarHBondContact O-N 2.94Å; F86-Y88 VanDerWaalsContact C-N 3.29Å; F86-Y88 PolarHBondContact O-N 3Å; Y88-N90 VanDerWaalsContact C-N 3.29Å; Y88-N90 PolarHBondContact O-N 2.8Å; Y88-K91 PolarHBondContact O-N 3.24Å; Y88-T92 HydrophobicContact CD1-CG2 3.77Å; Y88-T92 HydrophobicContact CE1-CG2 3.74Å; Y88-R286 PolarHBondContact OH-NH1 3.07Å
89	F	94.4	Very high	94.9	Very high	119 Å²	119	49.1 Å²	49.1	52%	0.522	26%	0.256	S	S	.	.	H	α-helix	trans	-62.5	-39.3	170.9	-80.5	-53.8	0	0	0	111.8	P32 I36 I85 F86 K91	P32-F89 HydrophobicContact CB-CD2 4.37Å; P32-F89 HydrophobicContact CB-CE1 4.09Å; P32-F89 HydrophobicContact CB-CE2 3.97Å; P32-F89 HydrophobicContact CB-CZ 3.8Å; I36-F89 HydrophobicContact CD1-CE2 3.96Å; I36-F89 HydrophobicContact CD1-CZ 3.98Å; I85-F89 HydrophobicContact CG2-CD2 3.67Å; I85-F89 HydrophobicContact CG2-CE2 3.5Å; I85-F89 VanDerWaalsContact CG2-CE2 3.5Å; I85-F89 WeakPolarHBondContact O-CD2 3.33Å; I85-F89 PolarHBondContact O-N 3.42Å; F86-F89 PolarHBondContact O-N 3.21Å; F89-K91 PolarHBondContact O-N 2.8Å
90	N	93.6	Very high	94.8	Very high	57 Å²	57	47.9 Å²	47.9	31%	0.305	25%	0.249	S	C	.	.	T	Hydrogen-bonded Turn	trans	-77.9	31.8	175.6	-160.1	31.7	0	0	0	112.8	F86 Y87 Y88 T92 N93	F86-N90 HydrophobicContact CD1-CB 4.26Å; F86-N90 HydrophobicContact CE1-CB 3.93Å; F86-N90 HydrophobicContact CZ-CB 4.5Å; F86-N90 VanDerWaalsContact O-CB 3.27Å; F86-N90 WeakPolarHBondContact O-CB 3.43Å; F86-N90 PolarHBondContact O-N 3.35Å; Y87-N90 CarbonylContact O-C 3.56Å; Y88-N90 VanDerWaalsContact C-N 3.29Å; Y88-N90 PolarHBondContact O-N 2.8Å; N90-T92 PolarHBondContact O-N 3.28Å; N90-T92 VanDerWaalsContact O-N 3.11Å; N90-N93 PolarHBondContact ND2-O 3.14Å; N90-N93 WeakPolarHBondContact O-CB 3.17Å; N90-N93 PolarHBondContact O-N 3.24Å
91	K	89.7	Confident	94.8	Very high	104 Å²	104	47.6 Å²	47.6	45%	0.452	25%	0.247	S	C	.	.	T	Hydrogen-bonded Turn	trans	50.3	40	176.6	-54.5	-58.7	-176.4	-173.9	0	114	F28 Y88 F89 N93	F28-K91 HydrophobicContact CD2-CD 4.2Å; F28-K91 HydrophobicContact CG-CD 4.33Å; Y88-K91 PolarHBondContact O-N 3.24Å; F89-K91 PolarHBondContact O-N 2.8Å; K91-N93 VanDerWaalsContact C-N 3.31Å; K91-N93 PolarHBondContact O-N 3.46Å
92	T	89.9	Confident	94.7	Very high	6 Å²	6	51.1 Å²	51.1	4%	0.037	26%	0.26	C	S	.	.	T	Hydrogen-bonded Turn	trans	62.4	33.4	-176.8	55.8	0	0	0	0	114.2	K23 F28 Y87 Y88 N90	K23-T92 PolarHBondContact NZ-OG1 3.49Å; F28-T92 HydrophobicContact CD1-CG2 4.1Å; F28-T92 HydrophobicContact CE1-CG2 3.58Å; Y87-T92 HydrophobicContact CD1-CG2 4.33Å; Y87-T92 HydrophobicContact CE1-CG2 3.66Å; Y87-T92 VanDerWaalsContact CE2-CA 3.41Å; Y87-T92 HydrophobicContact CE2-CG2 4.43Å; Y87-T92 WeakPolarHBondContact CE2-O 3.46Å; Y87-T92 WeakPolarHBondContact O-CA 3.42Å; Y87-T92 PolarHBondContact O-N 2.62Å; Y87-T92 WeakPolarHBondContact OH-CB 3.25Å; Y88-T92 HydrophobicContact CD1-CG2 3.77Å; Y88-T92 HydrophobicContact CE1-CG2 3.74Å; N90-T92 PolarHBondContact O-N 3.28Å; N90-T92 VanDerWaalsContact O-N 3.11Å
93	N	92.7	Very high	94.6	Very high	36 Å²	36	52 Å²	52	19%	0.193	26%	0.262	C	S	.	.			trans	-100	112.9	168.6	-173.6	25.3	0	0	0	110.7	N90 K91 L175 T176	N90-N93 PolarHBondContact ND2-O 3.14Å; N90-N93 WeakPolarHBondContact O-CB 3.17Å; N90-N93 PolarHBondContact O-N 3.24Å; K91-N93 VanDerWaalsContact C-N 3.31Å; K91-N93 PolarHBondContact O-N 3.46Å; N93-L175 HydrophobicContact CB-CB 4.3Å; N93-L175 HydrophobicContact CB-CD2 4Å; N93-T176 CarbonylContact C-O 3.5Å; N93-T176 WeakPolarHBondContact CA-O 3.38Å; N93-T176 PolarHBondContact OD1-N 3.21Å
94	W	94.8	Very high	94.6	Very high	4 Å²	4	49 Å²	49	2%	0.015	25%	0.248	C	C	.	.			trans	-90.2	111.5	-177.2	-175.3	-89.7	0	0	0	111.1	F83 Y87 F96 G97 L100 C101 Q104 T169 T176 C178	F83-W94 HydrophobicContact CB-CH2 3.9Å; F83-W94 HydrophobicContact CB-CZ3 4.3Å; Y87-W94 HydrophobicContact CD2-CB 3.83Å; Y87-W94 HydrophobicContact CD2-CD2 4.48Å; Y87-W94 AromaticContact CD2-CE3 3.74Å; Y87-W94 HydrophobicContact CD2-CE3 3.74Å; Y87-W94 HydrophobicContact CE2-CB 3.88Å; Y87-W94 HydrophobicContact CE2-CE3 4.41Å; Y87-W94 AromaticContact CG-CE3 3.88Å; Y87-W94 HydrophobicContact CG-CE3 3.88Å; Y87-W94 HydrophobicContact CG-CZ3 4.44Å; W94-F96 HydrophobicContact CD2-CD2 4.12Å; W94-F96 AromaticContact CE2-CD2 3.95Å; W94-F96 HydrophobicContact CE3-CD2 4.19Å; W94-F96 AromaticContact CH2-CD2 3.96Å; W94-F96 HydrophobicContact CH2-CD2 3.96Å; W94-F96 HydrophobicContact CZ2-CB 3.78Å; W94-F96 AromaticContact CZ2-CD2 3.88Å; W94-F96 HydrophobicContact CZ2-CD2 3.88Å; W94-F96 HydrophobicContact CZ2-CG 4.29Å; W94-F96 HydrophobicContact CZ3-CD2 4.11Å; W94-G97 PolarHBondContact NE1-O 2.7Å; W94-L100 VanDerWaalsContact CZ2-C 3.47Å; W94-L100 HydrophobicContact CZ2-CB 3.92Å; W94-C101 HydrophobicContact CD2-CB 4.4Å; W94-C101 HydrophobicContact CZ2-CB 4.11Å; W94-C101 VanDerWaalsContact CZ2-N 3.35Å; W94-Q104 HydrophobicContact CH2-CB 3.99Å; W94-Q104 HydrophobicContact CH2-CG 4.11Å; W94-Q104 HydrophobicContact CZ3-CG 4.48Å; W94-T169 HydrophobicContact CG-CG2 4.37Å; W94-T176 WeakPolarHBondContact CB-O 3.34Å; W94-T176 PolarHBondContact N-O 2.98Å; W94-T176 WeakPolarHBondContact O-CB 3.32Å; W94-C178 HydrophobicContact CB-CB 3.87Å; W94-C178 HydrophobicContact CD2-CB 3.63Å; W94-C178 HydrophobicContact CE3-CB 3.78Å; W94-C178 HydrophobicContact CG-CB 3.67Å
95	I	95.6	Very high	94.6	Very high	97 Å²	97	49 Å²	49	50%	0.497	25%	0.248	S	C	.	.			trans	-103.4	-6.3	-175.8	65.1	168.5	0	0	0	114	F86 G97	F86-I95 HydrophobicContact CD1-CD1 4.38Å; F86-I95 HydrophobicContact CD1-CG1 4.46Å; F86-I95 HydrophobicContact CE1-CD1 3.4Å; F86-I95 VanDerWaalsContact CE1-CD1 3.4Å; F86-I95 HydrophobicContact CE1-CG1 3.81Å; F86-I95 HydrophobicContact CZ-CD1 3.73Å; I95-G97 VanDerWaalsContact C-N 3.26Å; I95-G97 PolarHBondContact O-N 3.24Å
96	F	95.1	Very high	94.6	Very high	61 Å²	61	49.5 Å²	49.5	27%	0.268	25%	0.25	S	C	.	.	S	Bend	trans	-86.1	7.5	-171.3	-53.2	-70.9	0	0	0	113.9	F83 F86 W94 L100	F83-F96 HydrophobicContact CB-CD2 4.39Å; F83-F96 HydrophobicContact CB-CE2 4.26Å; F83-F96 AromaticContact CD1-CD1 3.91Å; F83-F96 HydrophobicContact CD1-CD1 3.91Å; F83-F96 AromaticContact CD1-CD2 3.92Å; F83-F96 HydrophobicContact CD1-CD2 3.92Å; F83-F96 AromaticContact CD1-CE1 3.98Å; F83-F96 HydrophobicContact CD1-CE1 3.98Å; F83-F96 AromaticContact CD1-CE2 3.99Å; F83-F96 HydrophobicContact CD1-CE2 3.99Å; F83-F96 AromaticContact CD1-CG 3.88Å; F83-F96 HydrophobicContact CD1-CG 3.88Å; F83-F96 HydrophobicContact CD1-CZ 4.02Å; F83-F96 HydrophobicContact CE1-CD1 4.15Å; F83-F96 HydrophobicContact CE1-CE1 4.34Å; F83-F96 HydrophobicContact CE1-CG 4.42Å; F86-F96 HydrophobicContact CB-CE2 4.25Å; F86-F96 HydrophobicContact CB-CZ 4Å; F86-F96 AromaticContact CD1-CE2 3.69Å; F86-F96 HydrophobicContact CD1-CE2 3.69Å; F86-F96 AromaticContact CD1-CZ 3.45Å; F86-F96 HydrophobicContact CD1-CZ 3.45Å; F86-F96 VanDerWaalsContact CD1-CZ 3.45Å; F86-F96 HydrophobicContact CE1-CE2 4.49Å; F86-F96 HydrophobicContact CE1-CZ 4.12Å; F86-F96 HydrophobicContact CG-CE2 4.26Å; F86-F96 AromaticContact CG-CZ 3.79Å; F86-F96 HydrophobicContact CG-CZ 3.79Å; W94-F96 HydrophobicContact CD2-CD2 4.12Å; W94-F96 AromaticContact CE2-CD2 3.95Å; W94-F96 HydrophobicContact CE3-CD2 4.19Å; W94-F96 AromaticContact CH2-CD2 3.96Å; W94-F96 HydrophobicContact CH2-CD2 3.96Å; W94-F96 HydrophobicContact CZ2-CB 3.78Å; W94-F96 AromaticContact CZ2-CD2 3.88Å; W94-F96 HydrophobicContact CZ2-CD2 3.88Å; W94-F96 HydrophobicContact CZ2-CG 4.29Å; W94-F96 HydrophobicContact CZ3-CD2 4.11Å; F96-L100 HydrophobicContact CB-CB 4.02Å; F96-L100 HydrophobicContact CB-CD1 3.77Å; F96-L100 WeakPolarHBondContact O-CD1 3.22Å
97	G	94.6	Very high	94.7	Very high	38 Å²	38	47.2 Å²	47.2	39%	0.392	24%	0.241	S	C	.	.	H	α-helix	trans	77.7	170	-179.2	0	0	0	0	0	114.8	W94 I95 C101	W94-G97 PolarHBondContact NE1-O 2.7Å; I95-G97 VanDerWaalsContact C-N 3.26Å; I95-G97 PolarHBondContact O-N 3.24Å; G97-C101 PolarHBondContact O-N 3.4Å
98	D	93.9	Very high	94.7	Very high	47 Å²	47	47.5 Å²	47.5	25%	0.251	24%	0.242	S	C	.	.	H	α-helix	trans	-67.3	-40.4	-170.1	-166.8	59.9	0	0	0	113.5	L100 C101 R102 R168 T169	D98-L100 PolarHBondContact O-N 3.31Å; D98-C101 WeakPolarHBondContact O-CB 3.46Å; D98-C101 PolarHBondContact O-N 3.35Å; D98-C101 VanDerWaalsContact O-N 3.16Å; D98-R102 PolarHBondContact O-N 2.91Å; D98-R102 IonicContact OD2-CZ 3.56Å; D98-R102 IonicContact OD2-NE 3.19Å; D98-R102 PolarHBondContact OD2-NE 3.21Å; D98-R102 IonicContact OD2-NH2 2.7Å; D98-R102 PolarHBondContact OD2-NH2 2.92Å; D98-R168 WeakPolarHBondContact OD1-CA 3.25Å; D98-T169 HydrophobicContact CB-CG2 4.42Å; D98-T169 WeakPolarHBondContact CB-OG1 3.46Å; D98-T169 PolarHBondContact OD1-N 3.19Å; D98-T169 PolarHBondContact OD1-OG1 3.44Å
99	V	95.4	Very high	94.8	Very high	114 Å²	114	47.1 Å²	47.1	69%	0.691	24%	0.241	S	C	*	.	H	α-helix	trans	-60.1	-47.1	-179.3	177	0	0	0	0	111.3	C101 R102 L103	V99-C101 VanDerWaalsContact C-N 3.32Å; V99-C101 PolarHBondContact O-N 3.31Å; V99-R102 PolarHBondContact O-N 2.57Å; V99-L103 WeakPolarHBondContact O-CB 3.34Å; V99-L103 PolarHBondContact O-N 3.12Å
100	L	95.9	Very high	94.9	Very high	60 Å²	60	42.1 Å²	42.1	31%	0.314	22%	0.22	S	C	.	.	H	α-helix	trans	-69.4	-30.4	178.6	-73.3	176.8	0	0	0	112	F83 W94 F96 D98 L103 Q104	F83-L100 HydrophobicContact CE1-CD1 4.18Å; W94-L100 VanDerWaalsContact CZ2-C 3.47Å; W94-L100 HydrophobicContact CZ2-CB 3.92Å; F96-L100 HydrophobicContact CB-CB 4.02Å; F96-L100 HydrophobicContact CB-CD1 3.77Å; F96-L100 WeakPolarHBondContact O-CD1 3.22Å; D98-L100 PolarHBondContact O-N 3.31Å; L100-L103 HydrophobicContact CD2-CD2 4.38Å; L100-Q104 WeakPolarHBondContact O-CB 3.37Å; L100-Q104 PolarHBondContact O-N 3.46Å
101	C	95.6	Very high	95.1	Very high	0 Å²	0	39.7 Å²	39.7	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-62.3	-50.1	172.3	172.3	0	0	0	0	110.9	W94 G97 D98 V99 L103 Q104 R105 T169 C178	W94-C101 HydrophobicContact CD2-CB 4.4Å; W94-C101 HydrophobicContact CZ2-CB 4.11Å; W94-C101 VanDerWaalsContact CZ2-N 3.35Å; G97-C101 PolarHBondContact O-N 3.4Å; D98-C101 WeakPolarHBondContact O-CB 3.46Å; D98-C101 PolarHBondContact O-N 3.35Å; D98-C101 VanDerWaalsContact O-N 3.16Å; V99-C101 VanDerWaalsContact C-N 3.32Å; V99-C101 PolarHBondContact O-N 3.31Å; C101-L103 PolarHBondContact O-N 3.23Å; C101-Q104 PolarHBondContact O-N 3.38Å; C101-R105 WeakPolarHBondContact O-CG 3.46Å; C101-R105 PolarHBondContact O-N 3.02Å; C101-R105 VanDerWaalsContact O-N 3.09Å; C101-T169 HydrophobicContact CB-CG2 3.72Å; C101-C178 WeakPolarHBondContact CA-SG 3.44Å; C101-C178 HydrophobicContact CB-CB 3.84Å; C101-C178 WeakPolarHBondContact CB-SG 3.29Å; C101-C178 WeakPolarHBondContact SG-CA 3.49Å; C101-C178 WeakPolarHBondContact SG-CB 3.41Å; C101-C178 CovalentContact SG-SG 2.03Å; C101-C178 PolarHBondContact SG-SG 2.93Å
102	R	95.8	Very high	95.3	Very high	74 Å²	74	34.8 Å²	34.8	28%	0.279	19%	0.186	S	C	.	.	H	α-helix	trans	-57.1	-49.8	176.6	-73.2	172.8	-164.9	-117.4	7.4	111.5	D98 V99 Q104 R105 F106 L164 S167	D98-R102 PolarHBondContact O-N 2.91Å; D98-R102 IonicContact OD2-CZ 3.56Å; D98-R102 IonicContact OD2-NE 3.19Å; D98-R102 PolarHBondContact OD2-NE 3.21Å; D98-R102 IonicContact OD2-NH2 2.7Å; D98-R102 PolarHBondContact OD2-NH2 2.92Å; V99-R102 PolarHBondContact O-N 2.57Å; R102-Q104 VanDerWaalsContact C-N 3.34Å; R102-Q104 PolarHBondContact O-N 3.36Å; R102-R105 PolarHBondContact O-N 2.99Å; R102-F106 VanDerWaalsContact O-CB 3.29Å; R102-F106 WeakPolarHBondContact O-CB 3.34Å; R102-F106 PolarHBondContact O-N 3.42Å; R102-L164 HydrophobicContact CB-CD2 4.01Å; R102-L164 VanDerWaalsContact CD-O 3.25Å; R102-L164 WeakPolarHBondContact CD-O 3.37Å; R102-L164 PolarHBondContact NH1-O 2.79Å; R102-S167 WeakPolarHBondContact CG-O 3.32Å
103	L	96.3	Very high	95.6	Very high	74 Å²	74	34.7 Å²	34.7	39%	0.387	19%	0.185	S	C	.	.	H	α-helix	trans	-62.8	-41.1	-179.8	-174.5	60.9	0	0	0	111.6	V99 L100 C101 R105 F106 I107	V99-L103 WeakPolarHBondContact O-CB 3.34Å; V99-L103 PolarHBondContact O-N 3.12Å; L100-L103 HydrophobicContact CD2-CD2 4.38Å; C101-L103 PolarHBondContact O-N 3.23Å; L103-R105 PolarHBondContact O-N 3.27Å; L103-F106 HydrophobicContact CD1-CD1 4.35Å; L103-F106 PolarHBondContact O-N 2.94Å; L103-I107 HydrophobicContact CD1-CD1 3.9Å; L103-I107 HydrophobicContact CD1-CG1 3.99Å; L103-I107 HydrophobicContact CD2-CD1 4.34Å; L103-I107 HydrophobicContact CG-CD1 3.72Å; L103-I107 HydrophobicContact CG-CG1 4.23Å; L103-I107 WeakPolarHBondContact O-CB 3.35Å; L103-I107 VanDerWaalsContact O-CG1 3.3Å; L103-I107 WeakPolarHBondContact O-CG1 3.38Å; L103-I107 PolarHBondContact O-N 3.14Å
104	Q	96.3	Very high	95.8	Very high	6 Å²	6	33 Å²	33	3%	0.028	18%	0.176	C	C	.	.	H	α-helix	trans	-59.5	-44.3	176.9	-179.9	60.8	67.2	0	0	112.1	S80 W94 L100 C101 R102 F108	S80-Q104 PolarHBondContact O-OE1 3.11Å; S80-Q104 PolarHBondContact OG-NE2 2.74Å; W94-Q104 HydrophobicContact CH2-CB 3.99Å; W94-Q104 HydrophobicContact CH2-CG 4.11Å; W94-Q104 HydrophobicContact CZ3-CG 4.48Å; L100-Q104 WeakPolarHBondContact O-CB 3.37Å; L100-Q104 PolarHBondContact O-N 3.46Å; C101-Q104 PolarHBondContact O-N 3.38Å; R102-Q104 VanDerWaalsContact C-N 3.34Å; R102-Q104 PolarHBondContact O-N 3.36Å; Q104-F108 PolarHBondContact O-N 2.82Å
105	R	95.3	Very high	95.8	Very high	7 Å²	7	32.8 Å²	32.8	3%	0.026	18%	0.175	C	C	.	.	H	α-helix	trans	-70.8	-38.5	177.6	-60.9	-50.6	178.6	-175.6	2.2	112	C101 R102 L103 H109 I163 S167 C178 Y179 D180	C101-R105 WeakPolarHBondContact O-CG 3.46Å; C101-R105 PolarHBondContact O-N 3.02Å; C101-R105 VanDerWaalsContact O-N 3.09Å; R102-R105 PolarHBondContact O-N 2.99Å; L103-R105 PolarHBondContact O-N 3.27Å; R105-H109 PolarHBondContact O-N 3.05Å; R105-H109 PolarHBondContact O-ND1 3.02Å; R105-I163 HydrophobicContact CB-CG2 3.82Å; R105-S167 VanDerWaalsContact CB-OG 3.31Å; R105-S167 WeakPolarHBondContact CB-OG 3.38Å; R105-C178 PolarHBondContact NH2-O 2.68Å; R105-Y179 PolarHBondContact NE-O 3Å; R105-D180 IonicContact CZ-OD1 2.63Å; R105-D180 IonicContact NE-OD1 3.73Å; R105-D180 IonicContact NH1-OD1 3.22Å; R105-D180 PolarHBondContact NH1-OD1 3.49Å
106	F	96.9	Very high	95.8	Very high	30 Å²	30	28.2 Å²	28.2	13%	0.132	15%	0.152	C	C	.	.	H	α-helix	trans	-63.6	-50.8	177.3	178	-103.4	0	0	0	111.7	R102 L103 F108 H109 V110 V157 M160 L164	R102-F106 VanDerWaalsContact O-CB 3.29Å; R102-F106 WeakPolarHBondContact O-CB 3.34Å; R102-F106 PolarHBondContact O-N 3.42Å; L103-F106 HydrophobicContact CD1-CD1 4.35Å; L103-F106 PolarHBondContact O-N 2.94Å; F106-F108 VanDerWaalsContact C-N 3.32Å; F106-F108 PolarHBondContact O-N 2.94Å; F106-H109 PolarHBondContact O-N 3.21Å; F106-H109 VanDerWaalsContact O-N 3.16Å; F106-V110 HydrophobicContact CD1-CG2 4.05Å; F106-V110 HydrophobicContact CD2-CG2 4.13Å; F106-V110 HydrophobicContact CE1-CG2 3.68Å; F106-V110 HydrophobicContact CE2-CG2 3.76Å; F106-V110 HydrophobicContact CG-CG2 4.26Å; F106-V110 HydrophobicContact CZ-CG2 3.52Å; F106-V110 WeakPolarHBondContact O-CB 3.38Å; F106-V110 WeakPolarHBondContact O-CG2 3.38Å; F106-V110 PolarHBondContact O-N 3.02Å; F106-V157 HydrophobicContact CZ-CG1 4.27Å; F106-M160 HydrophobicContact CD2-CB 3.96Å; F106-M160 WeakPolarHBondContact CD2-O 3.23Å; F106-M160 HydrophobicContact CE2-CB 3.66Å; F106-L164 HydrophobicContact CB-CD2 3.62Å; F106-L164 HydrophobicContact CB-CG 4.22Å; F106-L164 HydrophobicContact CD1-CD2 4.47Å; F106-L164 HydrophobicContact CD2-CD1 4.23Å; F106-L164 HydrophobicContact CD2-CD2 4.17Å; F106-L164 HydrophobicContact CD2-CG 3.87Å; F106-L164 HydrophobicContact CE2-CD1 4.38Å; F106-L164 HydrophobicContact CE2-CG 4.47Å; F106-L164 HydrophobicContact CG-CD1 4.49Å; F106-L164 HydrophobicContact CG-CD2 3.85Å; F106-L164 HydrophobicContact CG-CG 4.07Å
107	I	97.3	Very high	95.9	Very high	41 Å²	41	27 Å²	27	21%	0.21	15%	0.148	C	C	.	.	H	α-helix	trans	-58	-43.6	178.5	-70.2	171.1	0	0	0	111.2	Y77 L103 H109 V110 N111	Y77-I107 HydrophobicContact CD2-CG2 4.45Å; L103-I107 HydrophobicContact CD1-CD1 3.9Å; L103-I107 HydrophobicContact CD1-CG1 3.99Å; L103-I107 HydrophobicContact CD2-CD1 4.34Å; L103-I107 HydrophobicContact CG-CD1 3.72Å; L103-I107 HydrophobicContact CG-CG1 4.23Å; L103-I107 WeakPolarHBondContact O-CB 3.35Å; L103-I107 VanDerWaalsContact O-CG1 3.3Å; L103-I107 WeakPolarHBondContact O-CG1 3.38Å; L103-I107 PolarHBondContact O-N 3.14Å; I107-H109 PolarHBondContact O-N 2.77Å; I107-V110 PolarHBondContact O-N 3.4Å; I107-N111 WeakPolarHBondContact O-CB 3.22Å; I107-N111 PolarHBondContact O-N 2.8Å
108	F	95.6	Very high	95.9	Very high	14 Å²	14	25.2 Å²	25.2	6%	0.061	13%	0.129	C	C	.	.	H	α-helix	trans	-57.4	-47.2	177	169.9	-103.2	0	0	0	112.1	Y77 Q104 F106 N111 L112 F252 A289	Y77-F108 HydrophobicContact CD2-CB 4.42Å; Y77-F108 HydrophobicContact CD2-CD2 4.41Å; Y77-F108 HydrophobicContact CE2-CB 4.13Å; Y77-F108 AromaticContact CE2-CD2 3.61Å; Y77-F108 HydrophobicContact CE2-CD2 3.61Å; Y77-F108 HydrophobicContact CE2-CG 4.36Å; Y77-F108 AromaticContact CZ-CD2 3.82Å; Q104-F108 PolarHBondContact O-N 2.82Å; F106-F108 VanDerWaalsContact C-N 3.32Å; F106-F108 PolarHBondContact O-N 2.94Å; F108-N111 PolarHBondContact O-N 2.99Å; F108-L112 WeakPolarHBondContact O-CB 3.46Å; F108-L112 PolarHBondContact O-N 2.96Å; F108-F252 HydrophobicContact CE1-CE1 4.49Å; F108-F252 HydrophobicContact CE1-CE2 4.18Å; F108-F252 AromaticContact CE1-CZ 3.75Å; F108-F252 HydrophobicContact CE1-CZ 3.75Å; F108-F252 HydrophobicContact CZ-CE2 4.02Å; F108-F252 AromaticContact CZ-CZ 3.92Å; F108-F252 HydrophobicContact CZ-CZ 3.92Å; F108-A289 HydrophobicContact CZ-CB 4.37Å
109	H	95.7	Very high	95.7	Very high	1 Å²	1	23 Å²	23	1%	0.005	12%	0.118	C	C	.	.	H	α-helix	trans	-75.1	-34.3	-179	-70.7	88.7	0	0	0	112.6	R105 F106 I107 N111 L112 Y113 M160 I163 K256	R105-H109 PolarHBondContact O-N 3.05Å; R105-H109 PolarHBondContact O-ND1 3.02Å; F106-H109 PolarHBondContact O-N 3.21Å; F106-H109 VanDerWaalsContact O-N 3.16Å; I107-H109 PolarHBondContact O-N 2.77Å; H109-N111 VanDerWaalsContact C-N 3.32Å; H109-L112 PolarHBondContact O-N 3.3Å; H109-Y113 HydrophobicContact CB-CD2 4.44Å; H109-Y113 VanDerWaalsContact O-CD2 3.29Å; H109-Y113 WeakPolarHBondContact O-CD2 3.32Å; H109-Y113 PolarHBondContact O-N 3.24Å; H109-M160 HydrophobicContact CB-CG 4.18Å; H109-M160 HydrophobicContact CB-SD 3.64Å; H109-I163 HydrophobicContact CB-CD1 3.28Å; H109-K256 PolarHBondContact NE2-NZ 3.34Å
110	V	97.3	Very high	95.6	Very high	14 Å²	14	18.2 Å²	18.2	9%	0.085	9%	0.089	C	C	.	.	H	α-helix	trans	-60.9	-43.6	172	166.9	0	0	0	0	110.6	F106 I107 G114 W153 V156 M160	F106-V110 HydrophobicContact CD1-CG2 4.05Å; F106-V110 HydrophobicContact CD2-CG2 4.13Å; F106-V110 HydrophobicContact CE1-CG2 3.68Å; F106-V110 HydrophobicContact CE2-CG2 3.76Å; F106-V110 HydrophobicContact CG-CG2 4.26Å; F106-V110 HydrophobicContact CZ-CG2 3.52Å; F106-V110 WeakPolarHBondContact O-CB 3.38Å; F106-V110 WeakPolarHBondContact O-CG2 3.38Å; F106-V110 PolarHBondContact O-N 3.02Å; I107-V110 PolarHBondContact O-N 3.4Å; V110-G114 VanDerWaalsContact O-CA 3.31Å; V110-G114 WeakPolarHBondContact O-CA 3.42Å; V110-G114 PolarHBondContact O-N 3.41Å; V110-W153 HydrophobicContact CG1-CE3 4.45Å; V110-W153 HydrophobicContact CG1-CZ3 3.71Å; V110-V156 HydrophobicContact CB-CG1 4.14Å; V110-V156 HydrophobicContact CG1-CG1 3.94Å; V110-V156 HydrophobicContact CG2-CG1 4.2Å; V110-V156 WeakPolarHBondContact O-CG1 3.43Å; V110-M160 HydrophobicContact CG2-CB 3.81Å; V110-M160 HydrophobicContact CG2-CG 3.98Å
111	N	96.6	Very high	95.5	Very high	5 Å²	5	16.4 Å²	16.4	3%	0.027	8%	0.08	C	C	.	.	H	α-helix	trans	-61.9	-53.1	172.9	170.2	-96.5	0	0	0	111.2	A73 D74 Y77 I107 F108 H109 Y113 G114 S115	A73-N111 VanDerWaalsContact C-ND2 3.26Å; A73-N111 PolarHBondContact O-ND2 3.04Å; A73-N111 VanDerWaalsContact O-ND2 3.08Å; D74-N111 VanDerWaalsContact CA-ND2 3.31Å; D74-N111 WeakPolarHBondContact CA-ND2 3.48Å; D74-N111 PolarHBondContact N-ND2 3.1Å; D74-N111 PolarHBondContact OD1-ND2 3.06Å; Y77-N111 HydrophobicContact CG-CB 4.1Å; I107-N111 WeakPolarHBondContact O-CB 3.22Å; I107-N111 PolarHBondContact O-N 2.8Å; F108-N111 PolarHBondContact O-N 2.99Å; H109-N111 VanDerWaalsContact C-N 3.32Å; N111-Y113 PolarHBondContact O-N 2.85Å; N111-G114 PolarHBondContact O-N 3.43Å; N111-S115 WeakPolarHBondContact O-CB 3.39Å; N111-S115 PolarHBondContact O-N 3.07Å; N111-S115 PolarHBondContact O-OG 3.48Å
112	L	95.2	Very high	95.2	Very high	2 Å²	2	16.6 Å²	16.6	1%	0.01	8%	0.081	C	C	.	.	H	α-helix	trans	-52.2	-55.5	-179	177.7	66.2	0	0	0	112.8	F108 H109 I116 Y249 F252	F108-L112 WeakPolarHBondContact O-CB 3.46Å; F108-L112 PolarHBondContact O-N 2.96Å; H109-L112 PolarHBondContact O-N 3.3Å; L112-I116 HydrophobicContact CD1-CD1 4.32Å; L112-I116 HydrophobicContact CG-CD1 4.36Å; L112-I116 WeakPolarHBondContact O-CD1 3.41Å; L112-I116 VanDerWaalsContact O-CG1 3.32Å; L112-I116 WeakPolarHBondContact O-CG1 3.43Å; L112-I116 PolarHBondContact O-N 3.05Å; L112-Y249 HydrophobicContact CD1-CD1 3.44Å; L112-Y249 VanDerWaalsContact CD1-CD1 3.44Å; L112-Y249 HydrophobicContact CD1-CE1 3.46Å; L112-Y249 VanDerWaalsContact CD1-CE1 3.46Å; L112-F252 HydrophobicContact CD2-CD1 3.87Å; L112-F252 HydrophobicContact CD2-CE1 3.37Å; L112-F252 HydrophobicContact CD2-CZ 4.22Å
113	Y	96.4	Very high	94.9	Very high	4 Å²	4	13 Å²	13	2%	0.016	7%	0.068	C	C	.	.	H	α-helix	trans	-77.8	-31.6	-177.3	-70.7	-73.2	0	0	0	112.6	H109 N111 I116 L117 M160 L197 G201 H253	H109-Y113 HydrophobicContact CB-CD2 4.44Å; H109-Y113 VanDerWaalsContact O-CD2 3.29Å; H109-Y113 WeakPolarHBondContact O-CD2 3.32Å; H109-Y113 PolarHBondContact O-N 3.24Å; N111-Y113 PolarHBondContact O-N 2.85Å; Y113-I116 HydrophobicContact CD1-CD1 4.35Å; Y113-I116 PolarHBondContact O-N 3.37Å; Y113-L117 WeakPolarHBondContact O-CG 3.04Å; Y113-L117 PolarHBondContact O-N 3.17Å; Y113-M160 HydrophobicContact CD1-CE 4.49Å; Y113-M160 HydrophobicContact CD2-CE 3.24Å; Y113-M160 HydrophobicContact CD2-CG 4.44Å; Y113-M160 HydrophobicContact CD2-SD 3.35Å; Y113-M160 WeakPolarHBondContact CD2-SD 3.5Å; Y113-M160 HydrophobicContact CE2-CE 3.66Å; Y113-M160 HydrophobicContact CE2-SD 3.73Å; Y113-M160 HydrophobicContact CG-CE 3.71Å; Y113-M160 HydrophobicContact CG-SD 4.32Å; Y113-L197 HydrophobicContact CE1-CB 4.35Å; Y113-L197 HydrophobicContact CE2-CB 4.45Å; Y113-L197 HydrophobicContact CE2-CD1 4Å; Y113-L197 WeakPolarHBondContact OH-CB 3.3Å; Y113-G201 WeakPolarHBondContact CD1-O 3.23Å; Y113-H253 AromaticContact CE1-NE2 3.71Å; Y113-H253 AromaticContact CZ-NE2 3.74Å; Y113-H253 PolarHBondContact OH-NE2 2.72Å
114	G	96.9	Very high	94.6	Very high	0 Å²	0	11.7 Å²	11.7	0%	0	6%	0.063	C	C	.	.	H	α-helix	trans	-58.2	-49	170.6	0	0	0	0	0	111.2	V110 N111 L117 F118	V110-G114 VanDerWaalsContact O-CA 3.31Å; V110-G114 WeakPolarHBondContact O-CA 3.42Å; V110-G114 PolarHBondContact O-N 3.41Å; N111-G114 PolarHBondContact O-N 3.43Å; G114-L117 PolarHBondContact O-N 2.91Å; G114-F118 WeakPolarHBondContact O-CB 3.48Å; G114-F118 WeakPolarHBondContact O-CD2 3.31Å; G114-F118 PolarHBondContact O-N 3.49Å
115	S	94.8	Very high	94.1	Very high	0 Å²	0	12.6 Å²	12.6	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-62.4	-45.3	179.1	-63.4	0	0	0	0	112	L70 N111 L117 F118 L119 Y249	L70-S115 VanDerWaalsContact CD1-CA 3.42Å; L70-S115 VanDerWaalsContact CD1-OG 3.31Å; L70-S115 WeakPolarHBondContact CD1-OG 3.47Å; N111-S115 WeakPolarHBondContact O-CB 3.39Å; N111-S115 PolarHBondContact O-N 3.07Å; N111-S115 PolarHBondContact O-OG 3.48Å; S115-L117 PolarHBondContact O-N 3.2Å; S115-F118 PolarHBondContact O-N 3.19Å; S115-L119 WeakPolarHBondContact O-CB 3.47Å; S115-L119 WeakPolarHBondContact O-CG 3.31Å; S115-L119 PolarHBondContact O-N 3.45Å; S115-Y249 WeakPolarHBondContact CB-OH 3.3Å
116	I	94.8	Very high	93.5	Very high	0 Å²	0	14.3 Å²	14.3	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-56.3	-47.7	174.7	-70.2	163.8	0	0	0	111.6	L112 Y113 T120 G201 F202 P205 F245 Y249	L112-I116 HydrophobicContact CD1-CD1 4.32Å; L112-I116 HydrophobicContact CG-CD1 4.36Å; L112-I116 WeakPolarHBondContact O-CD1 3.41Å; L112-I116 VanDerWaalsContact O-CG1 3.32Å; L112-I116 WeakPolarHBondContact O-CG1 3.43Å; L112-I116 PolarHBondContact O-N 3.05Å; Y113-I116 HydrophobicContact CD1-CD1 4.35Å; Y113-I116 PolarHBondContact O-N 3.37Å; I116-T120 WeakPolarHBondContact O-CB 3.29Å; I116-T120 PolarHBondContact O-N 2.87Å; I116-T120 PolarHBondContact O-OG1 2.9Å; I116-G201 WeakPolarHBondContact CG2-O 3.41Å; I116-F202 HydrophobicContact CD1-CD2 4.12Å; I116-P205 HydrophobicContact CG2-CB 3.39Å; I116-P205 HydrophobicContact CG2-CG 3.85Å; I116-F245 HydrophobicContact CB-CZ 4.42Å; I116-F245 HydrophobicContact CG1-CE1 4.33Å; I116-F245 HydrophobicContact CG1-CZ 4.17Å; I116-F245 HydrophobicContact CG2-CE1 4.27Å; I116-F245 HydrophobicContact CG2-CZ 4.04Å; I116-Y249 HydrophobicContact CD1-CD1 4.4Å; I116-Y249 HydrophobicContact CD1-CG 4.34Å; I116-Y249 HydrophobicContact CG1-CD1 4.44Å; I116-Y249 HydrophobicContact CG1-CD2 3.97Å; I116-Y249 HydrophobicContact CG1-CE1 4.3Å; I116-Y249 HydrophobicContact CG1-CE2 3.84Å; I116-Y249 HydrophobicContact CG1-CG 4.26Å
117	L	96.2	Very high	93	Very high	37 Å²	37	15.4 Å²	15.4	19%	0.194	8%	0.077	C	C	.	.	H	α-helix	trans	-71.2	-36.9	-178.6	-68.3	-179.3	0	0	0	112.9	Y113 G114 S115 T120 C121 V152 I155 V156 P205	Y113-L117 WeakPolarHBondContact O-CG 3.04Å; Y113-L117 PolarHBondContact O-N 3.17Å; G114-L117 PolarHBondContact O-N 2.91Å; S115-L117 PolarHBondContact O-N 3.2Å; L117-T120 WeakPolarHBondContact O-CB 3.38Å; L117-T120 PolarHBondContact O-N 2.68Å; L117-C121 PolarHBondContact O-N 2.9Å; L117-C121 PolarHBondContact O-SG 3.32Å; L117-V152 HydrophobicContact CB-CG1 3.77Å; L117-V152 HydrophobicContact CB-CG2 4.39Å; L117-V152 HydrophobicContact CD1-CG1 4.2Å; L117-I155 HydrophobicContact CD1-CG2 4.48Å; L117-V156 HydrophobicContact CD1-CG2 3.63Å; L117-P205 HydrophobicContact CD2-CG 3.92Å
118	F	94.6	Very high	92.4	Very high	0 Å²	0	14 Å²	14	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-68.1	-39.9	174.3	-76.8	-57.8	0	0	0	112	Y66 N69 L70 G114 S115 T120 C121 I122 V152 W153	Y66-F118 HydrophobicContact CD1-CD1 4.25Å; N69-F118 HydrophobicContact CB-CD1 4.07Å; N69-F118 HydrophobicContact CB-CD2 4.22Å; N69-F118 HydrophobicContact CB-CE1 3.51Å; N69-F118 HydrophobicContact CB-CE2 3.69Å; N69-F118 HydrophobicContact CB-CG 4.42Å; N69-F118 HydrophobicContact CB-CZ 3.33Å; L70-F118 HydrophobicContact CB-CB 4.28Å; L70-F118 HydrophobicContact CD1-CB 4.2Å; G114-F118 WeakPolarHBondContact O-CB 3.48Å; G114-F118 WeakPolarHBondContact O-CD2 3.31Å; G114-F118 PolarHBondContact O-N 3.49Å; S115-F118 PolarHBondContact O-N 3.19Å; F118-T120 VanDerWaalsContact C-N 3.27Å; F118-T120 PolarHBondContact O-N 3.01Å; F118-C121 WeakPolarHBondContact O-CB 3.42Å; F118-C121 PolarHBondContact O-N 2.85Å; F118-I122 VanDerWaalsContact O-CG1 3.26Å; F118-I122 WeakPolarHBondContact O-CG1 3.1Å; F118-I122 PolarHBondContact O-N 3.36Å; F118-V152 HydrophobicContact CD1-CG1 4.37Å; F118-V152 HydrophobicContact CD2-CG1 4.28Å; F118-V152 HydrophobicContact CE1-CB 4.14Å; F118-V152 HydrophobicContact CE1-CG1 3.97Å; F118-V152 HydrophobicContact CE2-CG1 3.85Å; F118-V152 HydrophobicContact CG-CG1 4.49Å; F118-V152 HydrophobicContact CZ-CB 4.07Å; F118-V152 HydrophobicContact CZ-CG1 3.65Å; F118-W153 HydrophobicContact CE2-CZ2 4.19Å; F118-W153 AromaticContact CZ-CD1 3.97Å; F118-W153 AromaticContact CZ-NE1 3.65Å
119	L	91.3	Very high	91.7	Very high	1 Å²	1	14.7 Å²	14.7	1%	0.005	8%	0.081	C	C	.	.	H	α-helix	trans	-61.6	-37	171.6	-71.8	174.2	0	0	0	111.7	L70 S115 I122 S123 I209 V241 F245 Y249 L299	L70-L119 HydrophobicContact CD2-CD2 3.99Å; L70-L119 HydrophobicContact CD2-CG 4.42Å; S115-L119 WeakPolarHBondContact O-CB 3.47Å; S115-L119 WeakPolarHBondContact O-CG 3.31Å; S115-L119 PolarHBondContact O-N 3.45Å; L119-I122 PolarHBondContact O-N 2.63Å; L119-S123 WeakPolarHBondContact O-CB 3.26Å; L119-S123 PolarHBondContact O-N 3.22Å; L119-S123 PolarHBondContact O-OG 3.45Å; L119-I209 HydrophobicContact CB-CD1 4.39Å; L119-V241 HydrophobicContact CD2-CG2 4.04Å; L119-F245 HydrophobicContact CB-CE2 4.45Å; L119-F245 HydrophobicContact CD1-CE2 4Å; L119-Y249 HydrophobicContact CD1-CE2 4.04Å; L119-L299 HydrophobicContact CD2-CD1 3.82Å
120	T	93.8	Very high	90.8	Very high	13 Å²	13	15.6 Å²	15.6	8%	0.08	9%	0.087	C	C	.	.	H	α-helix	trans	-63.6	-46.9	173	-55.4	0	0	0	0	111	I116 L117 F118 I122 S123 V124 P205 I208 I209	I116-T120 WeakPolarHBondContact O-CB 3.29Å; I116-T120 PolarHBondContact O-N 2.87Å; I116-T120 PolarHBondContact O-OG1 2.9Å; L117-T120 WeakPolarHBondContact O-CB 3.38Å; L117-T120 PolarHBondContact O-N 2.68Å; F118-T120 VanDerWaalsContact C-N 3.27Å; F118-T120 PolarHBondContact O-N 3.01Å; T120-I122 VanDerWaalsContact C-N 3.33Å; T120-I122 PolarHBondContact O-N 3.47Å; T120-S123 PolarHBondContact O-N 3.19Å; T120-V124 HydrophobicContact CG2-CG2 4.49Å; T120-V124 WeakPolarHBondContact O-CG2 3.5Å; T120-V124 PolarHBondContact O-N 3.26Å; T120-P205 WeakPolarHBondContact OG1-CB 3.31Å; T120-I208 HydrophobicContact CG2-CB 4.16Å; T120-I208 HydrophobicContact CG2-CD1 4.45Å; T120-I208 HydrophobicContact CG2-CG2 3.74Å; T120-I209 HydrophobicContact CG2-CG1 4.44Å
121	C	93.4	Very high	90.1	Very high	21 Å²	21	16.7 Å²	16.7	14%	0.142	9%	0.093	C	C	.	.	H	α-helix	trans	-59.9	-42.6	176.3	-68.3	0	0	0	0	111.9	Y66 L117 F118 H125	Y66-C121 HydrophobicContact CD1-CB 4.01Å; Y66-C121 HydrophobicContact CD2-CB 4.01Å; Y66-C121 HydrophobicContact CE1-CB 4Å; Y66-C121 HydrophobicContact CE2-CB 3.98Å; Y66-C121 HydrophobicContact CG-CB 4.02Å; L117-C121 PolarHBondContact O-N 2.9Å; L117-C121 PolarHBondContact O-SG 3.32Å; F118-C121 WeakPolarHBondContact O-CB 3.42Å; F118-C121 PolarHBondContact O-N 2.85Å; C121-H125 VanDerWaalsContact O-CB 3.23Å; C121-H125 WeakPolarHBondContact O-CB 3.47Å; C121-H125 PolarHBondContact O-N 3.06Å
122	I	88.9	Confident	89.3	Confident	4 Å²	4	19.5 Å²	19.5	2%	0.021	11%	0.107	C	C	.	.	H	α-helix	trans	-61.6	-45.3	175.4	-70.4	164.8	0	0	0	110.4	I63 Y66 M67 L70 F118 L119 T120 H125 R126 L237	I63-I122 HydrophobicContact CD1-CG2 4.1Å; I63-I122 HydrophobicContact CG1-CG1 4.41Å; I63-I122 HydrophobicContact CG1-CG2 4.43Å; Y66-I122 HydrophobicContact CD2-CG1 4.36Å; Y66-I122 HydrophobicContact CG-CG1 4.45Å; M67-I122 HydrophobicContact CG-CD1 4.05Å; L70-I122 HydrophobicContact CD2-CD1 4.36Å; F118-I122 VanDerWaalsContact O-CG1 3.26Å; F118-I122 WeakPolarHBondContact O-CG1 3.1Å; F118-I122 PolarHBondContact O-N 3.36Å; L119-I122 PolarHBondContact O-N 2.63Å; T120-I122 VanDerWaalsContact C-N 3.33Å; T120-I122 PolarHBondContact O-N 3.47Å; I122-H125 PolarHBondContact O-N 3.04Å; I122-R126 VanDerWaalsContact O-CG 3.29Å; I122-R126 WeakPolarHBondContact O-CG 3.3Å; I122-R126 PolarHBondContact O-N 2.78Å; I122-L237 HydrophobicContact CG2-CD2 4.05Å
123	S	88.4	Confident	88.3	Confident	0 Å²	0	23 Å²	23	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-62.9	-47	179.4	-58.4	0	0	0	0	112.1	L119 T120 H125 R126 Y127 Y213	L119-S123 WeakPolarHBondContact O-CB 3.26Å; L119-S123 PolarHBondContact O-N 3.22Å; L119-S123 PolarHBondContact O-OG 3.45Å; T120-S123 PolarHBondContact O-N 3.19Å; S123-H125 PolarHBondContact O-N 2.68Å; S123-R126 PolarHBondContact O-N 3.15Å; S123-Y127 WeakPolarHBondContact O-CB 3.23Å; S123-Y127 PolarHBondContact O-N 3.08Å; S123-Y213 PolarHBondContact OG-OH 2.87Å; S123-Y213 VanDerWaalsContact OG-OH 3.07Å
124	V	90.4	Very high	87	Confident	45 Å²	45	30 Å²	30	27%	0.273	17%	0.166	S	C	.	.	H	α-helix	trans	-64.3	-40.5	176.7	172.7	0	0	0	0	111.6	T120 R126 Y127 T128 I208	T120-V124 HydrophobicContact CG2-CG2 4.49Å; T120-V124 WeakPolarHBondContact O-CG2 3.5Å; T120-V124 PolarHBondContact O-N 3.26Å; V124-R126 VanDerWaalsContact C-N 3.34Å; V124-R126 PolarHBondContact O-N 3.33Å; V124-Y127 PolarHBondContact O-N 2.96Å; V124-T128 WeakPolarHBondContact O-CB 3.43Å; V124-T128 PolarHBondContact O-N 3.38Å; V124-T128 PolarHBondContact O-OG1 2.97Å; V124-I208 HydrophobicContact CG2-CG2 3.76Å
125	H	86.3	Confident	85.6	Confident	26 Å²	26	37.4 Å²	37.4	12%	0.12	20%	0.198	C	C	.	.	H	α-helix	trans	-60.4	-44.9	175.2	178.9	-56.5	0	0	0	110.9	S62 I63 Y66 C121 I122 S123 G129 L140	S62-H125 WeakPolarHBondContact CB-NE2 2.94Å; I63-H125 PolarHBondContact N-NE2 2.98Å; Y66-H125 HydrophobicContact CE2-CB 4.25Å; C121-H125 VanDerWaalsContact O-CB 3.23Å; C121-H125 WeakPolarHBondContact O-CB 3.47Å; C121-H125 PolarHBondContact O-N 3.06Å; I122-H125 PolarHBondContact O-N 3.04Å; S123-H125 PolarHBondContact O-N 2.68Å; H125-G129 PolarHBondContact O-N 2.94Å; H125-L140 HydrophobicContact CB-CD2 4.35Å
126	R	83.3	Confident	84.4	Confident	42 Å²	42	38.3 Å²	38.3	16%	0.158	21%	0.205	C	C	.	.	H	α-helix	trans	-65.8	-45.1	177.9	-71.5	-67.5	-171.9	-171.4	3.7	111.6	I63 I122 S123 V124 T128 G129 V130 I216 L237	I63-R126 HydrophobicContact CD1-CG 4.29Å; I63-R126 VanDerWaalsContact CD1-NH2 3.34Å; I122-R126 VanDerWaalsContact O-CG 3.29Å; I122-R126 WeakPolarHBondContact O-CG 3.3Å; I122-R126 PolarHBondContact O-N 2.78Å; S123-R126 PolarHBondContact O-N 3.15Å; V124-R126 VanDerWaalsContact C-N 3.34Å; V124-R126 PolarHBondContact O-N 3.33Å; R126-T128 VanDerWaalsContact C-N 3.34Å; R126-T128 PolarHBondContact O-N 3.08Å; R126-G129 PolarHBondContact O-N 2.96Å; R126-V130 WeakPolarHBondContact O-CG2 3.36Å; R126-V130 PolarHBondContact O-N 2.95Å; R126-I216 HydrophobicContact CB-CD1 4.18Å; R126-L237 HydrophobicContact CG-CD2 3.8Å
127	Y	85.9	Confident	82.9	Confident	54 Å²	54	44.6 Å²	44.6	21%	0.212	24%	0.238	C	C	.	.	H	α-helix	trans	-57.1	-48.7	176.6	162.8	-104.1	0	0	0	111.1	S123 V124 G129 V130 V131 H132 C212 M215 I216	S123-Y127 WeakPolarHBondContact O-CB 3.23Å; S123-Y127 PolarHBondContact O-N 3.08Å; V124-Y127 PolarHBondContact O-N 2.96Å; Y127-G129 VanDerWaalsContact C-N 3.32Å; Y127-G129 PolarHBondContact O-N 3.2Å; Y127-V130 PolarHBondContact O-N 2.96Å; Y127-V131 HydrophobicContact CD2-CB 4.04Å; Y127-V131 HydrophobicContact CD2-CG2 3.55Å; Y127-V131 HydrophobicContact CE2-CB 3.72Å; Y127-V131 HydrophobicContact CE2-CG1 3.92Å; Y127-V131 HydrophobicContact CE2-CG2 3.56Å; Y127-V131 WeakPolarHBondContact O-CB 3.28Å; Y127-V131 PolarHBondContact O-N 3.3Å; Y127-H132 AromaticContact CZ-CD2 3.89Å; Y127-H132 AromaticContact CZ-NE2 3.78Å; Y127-H132 PolarHBondContact OH-NE2 2.95Å; Y127-H132 VanDerWaalsContact OH-NE2 3.14Å; Y127-C212 HydrophobicContact CG-CB 4.44Å; Y127-M215 HydrophobicContact CD2-CB 3.87Å; Y127-M215 HydrophobicContact CE2-CB 3.61Å; Y127-M215 HydrophobicContact CE2-CE 4.28Å; Y127-M215 HydrophobicContact CE2-CG 4.2Å; Y127-I216 HydrophobicContact CD2-CG1 4.44Å
128	T	84.9	Confident	81.3	Confident	10 Å²	10	44.8 Å²	44.8	6%	0.061	25%	0.249	C	C	.	.	H	α-helix	trans	-61.9	-40.4	179.3	-54.2	0	0	0	0	111.6	V124 R126 H132 L140	V124-T128 WeakPolarHBondContact O-CB 3.43Å; V124-T128 PolarHBondContact O-N 3.38Å; V124-T128 PolarHBondContact O-OG1 2.97Å; R126-T128 VanDerWaalsContact C-N 3.34Å; R126-T128 PolarHBondContact O-N 3.08Å; T128-H132 CarbonylContact O-C 3.26Å; T128-H132 WeakPolarHBondContact O-CA 3.37Å; T128-H132 PolarHBondContact O-N 3.42Å; T128-L140 HydrophobicContact CG2-CD2 4.39Å
129	G	79.9	Confident	79.8	Confident	29 Å²	29	53 Å²	53	30%	0.299	28%	0.28	S	S	.	.	H	α-helix	trans	-70	-33.3	179.1	0	0	0	0	0	114.4	H125 R126 Y127	H125-G129 PolarHBondContact O-N 2.94Å; R126-G129 PolarHBondContact O-N 2.96Å; Y127-G129 VanDerWaalsContact C-N 3.32Å; Y127-G129 PolarHBondContact O-N 3.2Å
130	V	78.5	Confident	79.1	Confident	20 Å²	20	55 Å²	55	12%	0.121	29%	0.29	C	S	.	.	H	α-helix	trans	-85.6	-47	-178.8	174.3	0	0	0	0	111.6	R126 Y127 I216 A219 L220	R126-V130 WeakPolarHBondContact O-CG2 3.36Å; R126-V130 PolarHBondContact O-N 2.95Å; Y127-V130 PolarHBondContact O-N 2.96Å; V130-I216 HydrophobicContact CB-CG1 4.5Å; V130-I216 HydrophobicContact CG1-CG2 4.49Å; V130-A219 HydrophobicContact CG1-CB 4.47Å; V130-L220 HydrophobicContact CG1-CD2 4.2Å; V130-L220 HydrophobicContact CG1-CG 4.4Å
131	V	81	Confident	78.5	Confident	37 Å²	37	60.3 Å²	60.3	22%	0.224	31%	0.312	C	S	.	.	H	α-helix	trans	-89.8	-28.8	-171.4	-174.4	0	0	0	0	112.1	Y127 A219	Y127-V131 HydrophobicContact CD2-CB 4.04Å; Y127-V131 HydrophobicContact CD2-CG2 3.55Å; Y127-V131 HydrophobicContact CE2-CB 3.72Å; Y127-V131 HydrophobicContact CE2-CG1 3.92Å; Y127-V131 HydrophobicContact CE2-CG2 3.56Å; Y127-V131 WeakPolarHBondContact O-CB 3.28Å; Y127-V131 PolarHBondContact O-N 3.3Å; V131-A219 HydrophobicContact CG2-CB 3.87Å
132	H	80.6	Confident	78	Confident	65 Å²	65	64.4 Å²	64.4	30%	0.301	33%	0.327	S	S	.	.			trans	-129.8	58.9	-175.9	-61.2	-79	0	0	0	112.9	Y127 T128 L134 K135 S136	Y127-H132 AromaticContact CZ-CD2 3.89Å; Y127-H132 AromaticContact CZ-NE2 3.78Å; Y127-H132 PolarHBondContact OH-NE2 2.95Å; Y127-H132 VanDerWaalsContact OH-NE2 3.14Å; T128-H132 CarbonylContact O-C 3.26Å; T128-H132 WeakPolarHBondContact O-CA 3.37Å; T128-H132 PolarHBondContact O-N 3.42Å; H132-L134 VanDerWaalsContact C-N 3.33Å; H132-L134 PolarHBondContact O-N 3.2Å; H132-K135 HydrophobicContact CB-CB 4.17Å; H132-K135 HydrophobicContact CB-CD 4.44Å; H132-K135 PolarHBondContact O-N 3.42Å; H132-K135 VanDerWaalsContact O-N 3.14Å; H132-S136 WeakPolarHBondContact O-CB 3.33Å; H132-S136 PolarHBondContact O-N 3.49Å
133	P	73.2	Confident	78.1	Confident	75 Å²	75	71.7 Å²	71.7	49%	0.487	36%	0.359	S	S	.	.	H	α-helix	trans	-58.2	-37.4	-170.1	22.2	-33.6	0	0	0	114	S136	P133-S136 VanDerWaalsContact O-CB 3.26Å; P133-S136 WeakPolarHBondContact O-CB 3.35Å; P133-S136 PolarHBondContact O-N 2.87Å; P133-S136 PolarHBondContact O-OG 3.06Å
134	L	69.8	Low	78.1	Confident	151 Å²	151	74.7 Å²	74.7	79%	0.791	38%	0.375	S	S	*	.	H	α-helix	trans	-70.6	-39.7	178.5	-63.6	175.4	0	0	0	112.7	H132 S136	H132-L134 VanDerWaalsContact C-N 3.33Å; H132-L134 PolarHBondContact O-N 3.2Å; L134-S136 PolarHBondContact O-N 3.42Å
135	K	68.2	Low	78.2	Confident	155 Å²	155	72.6 Å²	72.6	67%	0.674	36%	0.362	S	S	*	.	H	α-helix	trans	-69.6	-21.8	173.6	-65.8	-179.5	178.3	174.2	0	112	H132 L137 R139	H132-K135 HydrophobicContact CB-CB 4.17Å; H132-K135 HydrophobicContact CB-CD 4.44Å; H132-K135 PolarHBondContact O-N 3.42Å; H132-K135 VanDerWaalsContact O-N 3.14Å; K135-L137 VanDerWaalsContact C-N 3.33Å; K135-L137 PolarHBondContact O-N 3.49Å; K135-R139 PolarHBondContact O-N 2.91Å
136	S	69.4	Low	78.6	Confident	19 Å²	19	74.9 Å²	74.9	13%	0.133	38%	0.378	C	S	.	.	H	α-helix	trans	-68.1	-30	-178.2	92.5	0	0	0	0	113.1	H132 P133 L134 G138 R139 L140	H132-S136 WeakPolarHBondContact O-CB 3.33Å; H132-S136 PolarHBondContact O-N 3.49Å; P133-S136 VanDerWaalsContact O-CB 3.26Å; P133-S136 WeakPolarHBondContact O-CB 3.35Å; P133-S136 PolarHBondContact O-N 2.87Å; P133-S136 PolarHBondContact O-OG 3.06Å; L134-S136 PolarHBondContact O-N 3.42Å; S136-G138 VanDerWaalsContact C-N 3.26Å; S136-G138 PolarHBondContact O-N 3.37Å; S136-R139 PolarHBondContact O-N 3.25Å; S136-L140 WeakPolarHBondContact O-CB 3.39Å; S136-L140 WeakPolarHBondContact O-CG 3.46Å; S136-L140 PolarHBondContact O-N 2.88Å
137	L	63.4	Low	79.2	Confident	133 Å²	133	77 Å²	77	70%	0.696	39%	0.392	S	S	*	.	H	α-helix	trans	-59.2	-33.4	-179.5	-69.8	163.4	0	0	0	113.3	K135	K135-L137 VanDerWaalsContact C-N 3.33Å; K135-L137 PolarHBondContact O-N 3.49Å
138	G	62.6	Low	79.7	Confident	41 Å²	41	76.7 Å²	76.7	42%	0.423	40%	0.395	S	S	.	.	H	α-helix	trans	-89.7	-42.5	176.5	0	0	0	0	0	114	S136 K141	S136-G138 VanDerWaalsContact C-N 3.26Å; S136-G138 PolarHBondContact O-N 3.37Å; G138-K141 WeakPolarHBondContact O-CD 3.4Å; G138-K141 WeakPolarHBondContact O-CG 3.22Å
139	R	63.2	Low	80.3	Confident	172 Å²	172	76.3 Å²	76.3	65%	0.649	39%	0.393	S	S	*	.	H	α-helix	trans	-81.5	-31.8	-171.5	-165.2	171	-179.5	171.6	-0.3	113.3	K135 S136 K141 N144	K135-R139 PolarHBondContact O-N 2.91Å; S136-R139 PolarHBondContact O-N 3.25Å; R139-K141 PolarHBondContact O-N 3.38Å; R139-N144 PolarHBondContact O-ND2 3.06Å; R139-N144 VanDerWaalsContact O-ND2 3.12Å
140	L	75.3	Confident	81.2	Confident	43 Å²	43	77.8 Å²	77.8	23%	0.225	40%	0.403	C	S	.	.	T	Hydrogen-bonded Turn	trans	-85.7	27.5	-179.7	-55.3	-174.6	0	0	0	113.1	S62 H125 T128 S136	S62-L140 WeakPolarHBondContact CB-O 3.41Å; S62-L140 VanDerWaalsContact OG-C 3.32Å; S62-L140 PolarHBondContact OG-O 2.8Å; H125-L140 HydrophobicContact CB-CD2 4.35Å; T128-L140 HydrophobicContact CG2-CD2 4.39Å; S136-L140 WeakPolarHBondContact O-CB 3.39Å; S136-L140 WeakPolarHBondContact O-CG 3.46Å; S136-L140 PolarHBondContact O-N 2.88Å
141	K	80.9	Confident	82.1	Confident	125 Å²	125	81.2 Å²	81.2	54%	0.543	42%	0.42	S	S	.	.			trans	-72.5	141.7	173.8	-73.4	179.5	-179.9	-179.2	0	111.1	S62 G138 R139 K143 N144 A145	S62-K141 PolarHBondContact OG-O 3.04Å; G138-K141 WeakPolarHBondContact O-CD 3.4Å; G138-K141 WeakPolarHBondContact O-CG 3.22Å; R139-K141 PolarHBondContact O-N 3.38Å; K141-K143 PolarHBondContact O-N 3.28Å; K141-N144 WeakPolarHBondContact O-CB 3.48Å; K141-N144 PolarHBondContact O-N 3.5Å; K141-A145 PolarHBondContact O-N 3.44Å
142	K	84.7	Confident	82.9	Confident	107 Å²	107	80 Å²	80	47%	0.465	41%	0.412	S	S	.	.	H	α-helix	trans	-53.1	-40.2	178.9	-178.3	-170.7	174.2	-170.5	0	112.3	S62 V65 N144 A145 V146	S62-K142 WeakPolarHBondContact OG-CA 3.37Å; S62-K142 PolarHBondContact OG-N 3.41Å; S62-K142 VanDerWaalsContact OG-N 3.08Å; V65-K142 HydrophobicContact CG2-CG 4.16Å; K142-N144 VanDerWaalsContact C-N 3.3Å; K142-N144 PolarHBondContact O-N 3.33Å; K142-A145 PolarHBondContact O-N 2.9Å; K142-A145 VanDerWaalsContact O-N 3.15Å; K142-V146 HydrophobicContact CG-CG2 4.47Å; K142-V146 WeakPolarHBondContact O-CG2 3.38Å; K142-V146 PolarHBondContact O-N 3.38Å
143	K	89.1	Confident	83.8	Confident	156 Å²	156	79.8 Å²	79.8	68%	0.678	41%	0.409	S	S	*	.	H	α-helix	trans	-56	-44.3	178.3	-173.9	178.4	178.3	-179.3	0	111.6	K141 V146 I147	K141-K143 PolarHBondContact O-N 3.28Å; K143-V146 PolarHBondContact O-N 3.21Å; K143-I147 HydrophobicContact CG-CD1 4.03Å; K143-I147 WeakPolarHBondContact O-CG1 3.27Å; K143-I147 PolarHBondContact O-N 2.88Å
144	N	90.1	Very high	85	Confident	64 Å²	64	81 Å²	81	34%	0.342	41%	0.411	S	S	.	.	H	α-helix	trans	-65.3	-42.4	178.8	-61.6	-1.7	0	0	0	110.7	R139 K141 K142 V146 I147 T148	R139-N144 PolarHBondContact O-ND2 3.06Å; R139-N144 VanDerWaalsContact O-ND2 3.12Å; K141-N144 WeakPolarHBondContact O-CB 3.48Å; K141-N144 PolarHBondContact O-N 3.5Å; K142-N144 VanDerWaalsContact C-N 3.3Å; K142-N144 PolarHBondContact O-N 3.33Å; N144-V146 VanDerWaalsContact C-N 3.32Å; N144-V146 PolarHBondContact O-N 3.31Å; N144-I147 PolarHBondContact O-N 3.44Å; N144-T148 WeakPolarHBondContact O-CB 3.42Å; N144-T148 PolarHBondContact O-N 3.42Å; N144-T148 PolarHBondContact O-OG1 3Å
145	A	92.3	Very high	86.3	Confident	1 Å²	1	78.2 Å²	78.2	1%	0.008	40%	0.396	C	S	.	.	H	α-helix	trans	-63.1	-36.9	178	0	0	0	0	0	113.1	S62 V65 Y66 K141 K142 S149	S62-A145 WeakPolarHBondContact O-CB 2.91Å; V65-A145 HydrophobicContact CB-CB 4.06Å; V65-A145 HydrophobicContact CG1-CB 4.34Å; V65-A145 HydrophobicContact CG2-CB 4.29Å; Y66-A145 HydrophobicContact CE1-CB 3.95Å; Y66-A145 WeakPolarHBondContact CE1-O 3.17Å; Y66-A145 HydrophobicContact CE2-CB 4.28Å; Y66-A145 WeakPolarHBondContact OH-CA 3.44Å; K141-A145 PolarHBondContact O-N 3.44Å; K142-A145 PolarHBondContact O-N 2.9Å; K142-A145 VanDerWaalsContact O-N 3.15Å; A145-S149 WeakPolarHBondContact O-CB 3.2Å; A145-S149 PolarHBondContact O-N 3.14Å; A145-S149 PolarHBondContact O-OG 3.29Å
146	V	94.9	Very high	87.7	Confident	74 Å²	74	71 Å²	71	45%	0.448	36%	0.364	S	S	.	.	H	α-helix	trans	-66	-47.5	174.5	173.6	0	0	0	0	110.8	V65 K142 K143 N144 S149 A150	V65-V146 HydrophobicContact CG1-CG2 4.08Å; V65-V146 HydrophobicContact CG2-CG2 4.25Å; K142-V146 HydrophobicContact CG-CG2 4.47Å; K142-V146 WeakPolarHBondContact O-CG2 3.38Å; K142-V146 PolarHBondContact O-N 3.38Å; K143-V146 PolarHBondContact O-N 3.21Å; N144-V146 VanDerWaalsContact C-N 3.32Å; N144-V146 PolarHBondContact O-N 3.31Å; V146-S149 PolarHBondContact O-N 2.99Å; V146-A150 PolarHBondContact O-N 3.23Å
147	I	96.1	Very high	89	Confident	86 Å²	86	73 Å²	73	44%	0.441	38%	0.376	S	S	.	.	H	α-helix	trans	-60.1	-49	177.3	-66.3	166.7	0	0	0	110.4	K143 N144 S149 A150 L151	K143-I147 HydrophobicContact CG-CD1 4.03Å; K143-I147 WeakPolarHBondContact O-CG1 3.27Å; K143-I147 PolarHBondContact O-N 2.88Å; N144-I147 PolarHBondContact O-N 3.44Å; I147-S149 VanDerWaalsContact C-N 3.31Å; I147-S149 PolarHBondContact O-N 3.49Å; I147-A150 PolarHBondContact O-N 2.83Å; I147-L151 HydrophobicContact CG2-CD1 4.21Å; I147-L151 WeakPolarHBondContact O-CG 3.48Å; I147-L151 PolarHBondContact O-N 2.79Å
148	T	95.9	Very high	90.7	Very high	47 Å²	47	71.5 Å²	71.5	29%	0.288	37%	0.367	S	S	.	.	H	α-helix	trans	-59.5	-41.1	177.1	-60.8	0	0	0	0	111.6	Y66 N144 A150 L151 V152	Y66-T148 HydrophobicContact CE1-CG2 4.11Å; N144-T148 WeakPolarHBondContact O-CB 3.42Å; N144-T148 PolarHBondContact O-N 3.42Å; N144-T148 PolarHBondContact O-OG1 3Å; T148-A150 PolarHBondContact O-N 3.23Å; T148-L151 PolarHBondContact O-N 3.06Å; T148-V152 HydrophobicContact CG2-CG2 4.5Å; T148-V152 WeakPolarHBondContact O-CG2 3.24Å; T148-V152 PolarHBondContact O-N 2.96Å
149	S	97.4	Very high	92.3	Very high	3 Å²	3	71.7 Å²	71.7	2%	0.021	36%	0.362	C	S	.	.	H	α-helix	trans	-64.6	-40.4	177.6	-57.4	0	0	0	0	112.2	Y66 A145 V146 I147 L151 V152 W153	Y66-S149 WeakPolarHBondContact CD1-OG 3.38Å; A145-S149 WeakPolarHBondContact O-CB 3.2Å; A145-S149 PolarHBondContact O-N 3.14Å; A145-S149 PolarHBondContact O-OG 3.29Å; V146-S149 PolarHBondContact O-N 2.99Å; I147-S149 VanDerWaalsContact C-N 3.31Å; I147-S149 PolarHBondContact O-N 3.49Å; S149-L151 VanDerWaalsContact C-N 3.34Å; S149-V152 PolarHBondContact O-N 3.26Å; S149-W153 PolarHBondContact O-N 3.45Å
150	A	98	Very high	93.9	Very high	60 Å²	60	63.6 Å²	63.6	50%	0.496	33%	0.332	S	S	.	.	H	α-helix	trans	-63	-41	174.8	0	0	0	0	0	111.8	V146 I147 T148 W153 L154	V146-A150 PolarHBondContact O-N 3.23Å; I147-A150 PolarHBondContact O-N 2.83Å; T148-A150 PolarHBondContact O-N 3.23Å; A150-W153 PolarHBondContact O-N 2.86Å; A150-L154 WeakPolarHBondContact O-CB 3.31Å; A150-L154 PolarHBondContact O-N 2.85Å
151	L	98	Very high	94.9	Very high	91 Å²	91	64.2 Å²	64.2	48%	0.476	34%	0.34	S	S	.	.	H	α-helix	trans	-64.3	-41.9	174.8	-68.5	173.3	0	0	0	112.2	I147 T148 S149 W153 L154 I155	I147-L151 HydrophobicContact CG2-CD1 4.21Å; I147-L151 WeakPolarHBondContact O-CG 3.48Å; I147-L151 PolarHBondContact O-N 2.79Å; T148-L151 PolarHBondContact O-N 3.06Å; S149-L151 VanDerWaalsContact C-N 3.34Å; L151-W153 PolarHBondContact O-N 3.08Å; L151-L154 PolarHBondContact O-N 2.85Å; L151-I155 WeakPolarHBondContact O-CB 3.47Å; L151-I155 WeakPolarHBondContact O-CD1 3.37Å; L151-I155 VanDerWaalsContact O-CG1 3.22Å; L151-I155 WeakPolarHBondContact O-CG1 3.32Å; L151-I155 PolarHBondContact O-N 3.29Å
152	V	98.2	Very high	95.6	Very high	11 Å²	11	60.4 Å²	60.4	7%	0.067	33%	0.328	C	S	.	.	H	α-helix	trans	-58.8	-48.8	175.5	168.3	0	0	0	0	110.3	L117 F118 T148 S149 L154 I155 V156	L117-V152 HydrophobicContact CB-CG1 3.77Å; L117-V152 HydrophobicContact CB-CG2 4.39Å; L117-V152 HydrophobicContact CD1-CG1 4.2Å; F118-V152 HydrophobicContact CD1-CG1 4.37Å; F118-V152 HydrophobicContact CD2-CG1 4.28Å; F118-V152 HydrophobicContact CE1-CB 4.14Å; F118-V152 HydrophobicContact CE1-CG1 3.97Å; F118-V152 HydrophobicContact CE2-CG1 3.85Å; F118-V152 HydrophobicContact CG-CG1 4.49Å; F118-V152 HydrophobicContact CZ-CB 4.07Å; F118-V152 HydrophobicContact CZ-CG1 3.65Å; T148-V152 HydrophobicContact CG2-CG2 4.5Å; T148-V152 WeakPolarHBondContact O-CG2 3.24Å; T148-V152 PolarHBondContact O-N 2.96Å; S149-V152 PolarHBondContact O-N 3.26Å; V152-L154 PolarHBondContact O-N 3.05Å; V152-I155 PolarHBondContact O-N 3.43Å; V152-V156 HydrophobicContact CG1-CG2 4.26Å; V152-V156 WeakPolarHBondContact O-CB 3.29Å; V152-V156 WeakPolarHBondContact O-CG2 3.42Å; V152-V156 PolarHBondContact O-N 3.02Å
153	W	98.3	Very high	96	Very high	62 Å²	62	55.3 Å²	55.3	24%	0.235	31%	0.305	C	S	.	.	H	α-helix	trans	-58.8	-46.2	176.7	-81.4	116.2	0	0	0	112.6	N69 A73 V110 F118 S149 A150 L151 V156 V157	N69-W153 PolarHBondContact OD1-NE1 3.29Å; A73-W153 HydrophobicContact CB-CH2 3.75Å; A73-W153 HydrophobicContact CB-CZ2 4.17Å; V110-W153 HydrophobicContact CG1-CE3 4.45Å; V110-W153 HydrophobicContact CG1-CZ3 3.71Å; F118-W153 HydrophobicContact CE2-CZ2 4.19Å; F118-W153 AromaticContact CZ-CD1 3.97Å; F118-W153 AromaticContact CZ-NE1 3.65Å; S149-W153 PolarHBondContact O-N 3.45Å; A150-W153 PolarHBondContact O-N 2.86Å; L151-W153 PolarHBondContact O-N 3.08Å; W153-V156 PolarHBondContact O-N 3.34Å; W153-V157 WeakPolarHBondContact O-CB 3.28Å; W153-V157 VanDerWaalsContact O-CG2 3.28Å; W153-V157 WeakPolarHBondContact O-CG2 3.46Å; W153-V157 PolarHBondContact O-N 3.47Å
154	L	98.3	Very high	96.2	Very high	100 Å²	100	51 Å²	51	52%	0.524	29%	0.29	S	S	.	.	H	α-helix	trans	-59.3	-49.9	178.1	-176.5	66.1	0	0	0	111.4	A150 L151 V152 V156 V157 I158	A150-L154 WeakPolarHBondContact O-CB 3.31Å; A150-L154 PolarHBondContact O-N 2.85Å; L151-L154 PolarHBondContact O-N 2.85Å; V152-L154 PolarHBondContact O-N 3.05Å; L154-V156 PolarHBondContact O-N 3.47Å; L154-V157 PolarHBondContact O-N 3.5Å; L154-I158 HydrophobicContact CD1-CD1 3.65Å; L154-I158 HydrophobicContact CD1-CG1 4.26Å; L154-I158 HydrophobicContact CG-CD1 3.8Å; L154-I158 WeakPolarHBondContact O-CB 3.08Å; L154-I158 VanDerWaalsContact O-CG1 3.25Å; L154-I158 WeakPolarHBondContact O-CG1 3.43Å; L154-I158 PolarHBondContact O-N 3.49Å
155	I	97.8	Very high	96.3	Very high	93 Å²	93	54.3 Å²	54.3	48%	0.477	30%	0.298	S	S	.	.	H	α-helix	trans	-59.3	-47.3	179.1	-70.8	165.1	0	0	0	110.4	L117 L151 V152 S159	L117-I155 HydrophobicContact CD1-CG2 4.48Å; L151-I155 WeakPolarHBondContact O-CB 3.47Å; L151-I155 WeakPolarHBondContact O-CD1 3.37Å; L151-I155 VanDerWaalsContact O-CG1 3.22Å; L151-I155 WeakPolarHBondContact O-CG1 3.32Å; L151-I155 PolarHBondContact O-N 3.29Å; V152-I155 PolarHBondContact O-N 3.43Å; I155-S159 WeakPolarHBondContact O-CB 3.44Å; I155-S159 PolarHBondContact O-N 3.2Å; I155-S159 PolarHBondContact O-OG 3.26Å
156	V	97.9	Very high	96.1	Very high	2 Å²	2	56 Å²	56	1%	0.012	31%	0.305	C	S	.	.	H	α-helix	trans	-66	-49.3	-177.7	172.1	0	0	0	0	110.8	V110 L117 V152 W153 L154 I158 S159 M160	V110-V156 HydrophobicContact CB-CG1 4.14Å; V110-V156 HydrophobicContact CG1-CG1 3.94Å; V110-V156 HydrophobicContact CG2-CG1 4.2Å; V110-V156 WeakPolarHBondContact O-CG1 3.43Å; L117-V156 HydrophobicContact CD1-CG2 3.63Å; V152-V156 HydrophobicContact CG1-CG2 4.26Å; V152-V156 WeakPolarHBondContact O-CB 3.29Å; V152-V156 WeakPolarHBondContact O-CG2 3.42Å; V152-V156 PolarHBondContact O-N 3.02Å; W153-V156 PolarHBondContact O-N 3.34Å; L154-V156 PolarHBondContact O-N 3.47Å; V156-I158 PolarHBondContact O-N 3.46Å; V156-S159 PolarHBondContact O-N 2.99Å; V156-M160 HydrophobicContact CG1-CG 4.16Å; V156-M160 VanDerWaalsContact O-CB 3.26Å; V156-M160 WeakPolarHBondContact O-CB 3.24Å; V156-M160 WeakPolarHBondContact O-CG 3.37Å; V156-M160 PolarHBondContact O-N 3.01Å
157	V	97.6	Very high	95.9	Very high	62 Å²	62	52.5 Å²	52.5	38%	0.376	28%	0.283	S	S	.	.	H	α-helix	trans	-60.5	-46	-179.2	166.9	0	0	0	0	111	F106 W153 L154 M160 S161	F106-V157 HydrophobicContact CZ-CG1 4.27Å; W153-V157 WeakPolarHBondContact O-CB 3.28Å; W153-V157 VanDerWaalsContact O-CG2 3.28Å; W153-V157 WeakPolarHBondContact O-CG2 3.46Å; W153-V157 PolarHBondContact O-N 3.47Å; L154-V157 PolarHBondContact O-N 3.5Å; V157-M160 PolarHBondContact O-N 3.45Å; V157-S161 PolarHBondContact O-N 3.45Å
158	I	97.5	Very high	95.5	Very high	101 Å²	101	51.8 Å²	51.8	52%	0.518	28%	0.275	S	S	.	.	H	α-helix	trans	-63.1	-50.1	177.2	-68.7	173.1	0	0	0	110.4	L154 V156 M160 S161	L154-I158 HydrophobicContact CD1-CD1 3.65Å; L154-I158 HydrophobicContact CD1-CG1 4.26Å; L154-I158 HydrophobicContact CG-CD1 3.8Å; L154-I158 WeakPolarHBondContact O-CB 3.08Å; L154-I158 VanDerWaalsContact O-CG1 3.25Å; L154-I158 WeakPolarHBondContact O-CG1 3.43Å; L154-I158 PolarHBondContact O-N 3.49Å; V156-I158 PolarHBondContact O-N 3.46Å; I158-M160 PolarHBondContact O-N 3.06Å; I158-S161 WeakPolarHBondContact O-CB 3.37Å; I158-S161 PolarHBondContact O-N 3.35Å; I158-S161 VanDerWaalsContact O-N 3.13Å; I158-S161 PolarHBondContact O-OG 2.98Å
159	S	96.6	Very high	95.2	Very high	45 Å²	45	51.3 Å²	51.3	32%	0.315	27%	0.272	S	S	.	.	H	α-helix	trans	-64.6	-30.2	-176.7	-57.6	0	0	0	0	112.6	I155 V156 P162 Y193	I155-S159 WeakPolarHBondContact O-CB 3.44Å; I155-S159 PolarHBondContact O-N 3.2Å; I155-S159 PolarHBondContact O-OG 3.26Å; V156-S159 PolarHBondContact O-N 2.99Å; S159-P162 WeakPolarHBondContact O-CD 3.49Å; S159-Y193 WeakPolarHBondContact O-CE2 3.14Å; S159-Y193 PolarHBondContact O-OH 3.45Å
160	M	96.8	Very high	94.6	Very high	3 Å²	3	51.7 Å²	51.7	2%	0.015	28%	0.277	C	S	.	.	H	α-helix	trans	-88.5	-14	177.7	-64.4	-48.7	117.2	0	0	113.3	F106 H109 V110 Y113 V156 V157 I158 P162 I163 L197	F106-M160 HydrophobicContact CD2-CB 3.96Å; F106-M160 WeakPolarHBondContact CD2-O 3.23Å; F106-M160 HydrophobicContact CE2-CB 3.66Å; H109-M160 HydrophobicContact CB-CG 4.18Å; H109-M160 HydrophobicContact CB-SD 3.64Å; V110-M160 HydrophobicContact CG2-CB 3.81Å; V110-M160 HydrophobicContact CG2-CG 3.98Å; Y113-M160 HydrophobicContact CD1-CE 4.49Å; Y113-M160 HydrophobicContact CD2-CE 3.24Å; Y113-M160 HydrophobicContact CD2-CG 4.44Å; Y113-M160 HydrophobicContact CD2-SD 3.35Å; Y113-M160 WeakPolarHBondContact CD2-SD 3.5Å; Y113-M160 HydrophobicContact CE2-CE 3.66Å; Y113-M160 HydrophobicContact CE2-SD 3.73Å; Y113-M160 HydrophobicContact CG-CE 3.71Å; Y113-M160 HydrophobicContact CG-SD 4.32Å; V156-M160 HydrophobicContact CG1-CG 4.16Å; V156-M160 VanDerWaalsContact O-CB 3.26Å; V156-M160 WeakPolarHBondContact O-CB 3.24Å; V156-M160 WeakPolarHBondContact O-CG 3.37Å; V156-M160 PolarHBondContact O-N 3.01Å; V157-M160 PolarHBondContact O-N 3.45Å; I158-M160 PolarHBondContact O-N 3.06Å; M160-P162 VanDerWaalsContact C-N 3.3Å; M160-I163 HydrophobicContact CB-CD1 4.1Å; M160-I163 HydrophobicContact CG-CD1 4.37Å; M160-I163 WeakPolarHBondContact O-CB 3.13Å; M160-I163 WeakPolarHBondContact O-CG1 3.39Å; M160-I163 PolarHBondContact O-N 2.97Å; M160-I163 HydrophobicContact SD-CD1 3.62Å; M160-L197 HydrophobicContact CE-CD1 3.62Å; M160-L197 HydrophobicContact CE-CD2 3.47Å; M160-L197 VanDerWaalsContact CE-CD2 3.47Å; M160-L197 HydrophobicContact CE-CG 4.16Å; M160-L197 HydrophobicContact SD-CD1 3.98Å
161	S	96.4	Very high	93.8	Very high	56 Å²	56	54.5 Å²	54.5	39%	0.392	29%	0.29	S	S	.	.	T	Hydrogen-bonded Turn	trans	-54.9	-34.3	-179	69.8	0	0	0	0	114.7	V157 I158 I163 L164	V157-S161 PolarHBondContact O-N 3.45Å; I158-S161 WeakPolarHBondContact O-CB 3.37Å; I158-S161 PolarHBondContact O-N 3.35Å; I158-S161 VanDerWaalsContact O-N 3.13Å; I158-S161 PolarHBondContact O-OG 2.98Å; S161-I163 PolarHBondContact O-N 2.98Å; S161-I163 VanDerWaalsContact O-N 3.09Å; S161-L164 VanDerWaalsContact O-CB 3.31Å; S161-L164 WeakPolarHBondContact O-CB 3.36Å; S161-L164 PolarHBondContact O-N 3.48Å
162	P	95.3	Very high	92.9	Very high	44 Å²	44	54.7 Å²	54.7	29%	0.286	29%	0.287	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.5	-21.9	175.1	-24.4	36.6	0	0	0	113.8	S159 M160 L164 Y165 Y166 Y193	S159-P162 WeakPolarHBondContact O-CD 3.49Å; M160-P162 VanDerWaalsContact C-N 3.3Å; P162-L164 PolarHBondContact O-N 2.74Å; P162-Y165 WeakPolarHBondContact O-CA 2.97Å; P162-Y165 WeakPolarHBondContact O-CB 3.22Å; P162-Y165 PolarHBondContact O-N 2.99Å; P162-Y166 HydrophobicContact CB-CD2 4.1Å; P162-Y166 HydrophobicContact CB-CE2 4.07Å; P162-Y166 WeakPolarHBondContact O-CD2 3.42Å; P162-Y166 PolarHBondContact O-N 3.23Å; P162-Y193 HydrophobicContact CB-CE1 4.36Å; P162-Y193 HydrophobicContact CB-CE2 4.03Å; P162-Y193 HydrophobicContact CG-CE2 3.85Å
163	I	93.3	Very high	91.6	Very high	0 Å²	0	64.4 Å²	64.4	0%	0	32%	0.322	C	S	.	.	H	α-helix	trans	-62.4	-31.7	175.1	-62.8	170.1	0	0	0	110.9	R105 H109 M160 S161 Y165 Y166 S167 Y193	R105-I163 HydrophobicContact CB-CG2 3.82Å; H109-I163 HydrophobicContact CB-CD1 3.28Å; M160-I163 HydrophobicContact CB-CD1 4.1Å; M160-I163 HydrophobicContact CG-CD1 4.37Å; M160-I163 WeakPolarHBondContact O-CB 3.13Å; M160-I163 WeakPolarHBondContact O-CG1 3.39Å; M160-I163 PolarHBondContact O-N 2.97Å; M160-I163 HydrophobicContact SD-CD1 3.62Å; S161-I163 PolarHBondContact O-N 2.98Å; S161-I163 VanDerWaalsContact O-N 3.09Å; I163-Y165 PolarHBondContact O-N 3.46Å; I163-Y166 PolarHBondContact O-N 3.46Å; I163-S167 WeakPolarHBondContact CG2-OG 3.42Å; I163-S167 WeakPolarHBondContact O-CB 3.21Å; I163-S167 PolarHBondContact O-N 3.25Å; I163-S167 PolarHBondContact O-OG 2.92Å; I163-Y193 HydrophobicContact CG1-CE1 3.96Å; I163-Y193 WeakPolarHBondContact CG1-OH 3.33Å
164	L	93.6	Very high	90.6	Very high	66 Å²	66	69.8 Å²	69.8	35%	0.346	36%	0.355	S	S	.	.	H	α-helix	trans	-66.5	-24.4	174.4	-63.1	172	0	0	0	112	R102 F106 S161 P162	R102-L164 HydrophobicContact CB-CD2 4.01Å; R102-L164 VanDerWaalsContact CD-O 3.25Å; R102-L164 WeakPolarHBondContact CD-O 3.37Å; R102-L164 PolarHBondContact NH1-O 2.79Å; F106-L164 HydrophobicContact CB-CD2 3.62Å; F106-L164 HydrophobicContact CB-CG 4.22Å; F106-L164 HydrophobicContact CD1-CD2 4.47Å; F106-L164 HydrophobicContact CD2-CD1 4.23Å; F106-L164 HydrophobicContact CD2-CD2 4.17Å; F106-L164 HydrophobicContact CD2-CG 3.87Å; F106-L164 HydrophobicContact CE2-CD1 4.38Å; F106-L164 HydrophobicContact CE2-CG 4.47Å; F106-L164 HydrophobicContact CG-CD1 4.49Å; F106-L164 HydrophobicContact CG-CD2 3.85Å; F106-L164 HydrophobicContact CG-CG 4.07Å; S161-L164 VanDerWaalsContact O-CB 3.31Å; S161-L164 WeakPolarHBondContact O-CB 3.36Å; S161-L164 PolarHBondContact O-N 3.48Å; P162-L164 PolarHBondContact O-N 2.74Å
165	Y	91.3	Very high	90	Very high	134 Å²	134	68.2 Å²	68.2	53%	0.525	35%	0.348	S	S	.	.	H	α-helix	trans	-83	-50.8	172.9	172.3	-97.8	0	0	0	111.5	P162 I163	P162-Y165 WeakPolarHBondContact O-CA 2.97Å; P162-Y165 WeakPolarHBondContact O-CB 3.22Å; P162-Y165 PolarHBondContact O-N 2.99Å; I163-Y165 PolarHBondContact O-N 3.46Å
166	Y	89.6	Confident	89.5	Confident	37 Å²	37	66.5 Å²	66.5	15%	0.145	34%	0.341	C	S	.	.	H	α-helix	trans	-72.9	-35.7	-173.8	-73.8	-65.6	0	0	0	114.1	P162 I163 T182 E186 Y190 Y193	P162-Y166 HydrophobicContact CB-CD2 4.1Å; P162-Y166 HydrophobicContact CB-CE2 4.07Å; P162-Y166 WeakPolarHBondContact O-CD2 3.42Å; P162-Y166 PolarHBondContact O-N 3.23Å; I163-Y166 PolarHBondContact O-N 3.46Å; Y166-T182 HydrophobicContact CD1-CG2 4.44Å; Y166-T182 WeakPolarHBondContact O-CB 3.22Å; Y166-T182 PolarHBondContact O-OG1 2.97Å; Y166-E186 HydrophobicContact CD1-CB 4.15Å; Y166-E186 HydrophobicContact CE1-CB 4.2Å; Y166-Y190 HydrophobicContact CD1-CD2 4.04Å; Y166-Y190 HydrophobicContact CD1-CG 4.46Å; Y166-Y190 AromaticContact CD2-CD2 3.6Å; Y166-Y190 HydrophobicContact CD2-CD2 3.6Å; Y166-Y190 HydrophobicContact CD2-CE2 4.27Å; Y166-Y190 HydrophobicContact CE2-CD2 4.2Å; Y166-Y190 AromaticContact CG-CD2 3.5Å; Y166-Y190 HydrophobicContact CG-CD2 3.5Å; Y166-Y190 VanDerWaalsContact CG-CD2 3.5Å; Y166-Y190 HydrophobicContact CG-CE2 4.27Å; Y166-Y190 HydrophobicContact CG-CG 4.34Å; Y166-Y193 HydrophobicContact CD2-CD1 4.41Å; Y166-Y193 HydrophobicContact CE2-CD1 4.32Å; Y166-Y193 HydrophobicContact CE2-CG 4.48Å
167	S	89.1	Confident	89	Confident	0 Å²	0	67.1 Å²	67.1	0%	0	35%	0.345	C	S	.	.			trans	-75.3	132.2	177.2	-54.9	0	0	0	0	109.3	R102 R105 I163	R102-S167 WeakPolarHBondContact CG-O 3.32Å; R105-S167 VanDerWaalsContact CB-OG 3.31Å; R105-S167 WeakPolarHBondContact CB-OG 3.38Å; I163-S167 WeakPolarHBondContact CG2-OG 3.42Å; I163-S167 WeakPolarHBondContact O-CB 3.21Å; I163-S167 PolarHBondContact O-N 3.25Å; I163-S167 PolarHBondContact O-OG 2.92Å
168	R	89.2	Confident	88.6	Confident	70 Å²	70	64.2 Å²	64.2	26%	0.264	33%	0.327	S	S	.	.			trans	-155.4	162.8	177.1	51.3	-176	156.4	-165	-5.3	110.7	D98 Y179 T183	D98-R168 WeakPolarHBondContact OD1-CA 3.25Å; R168-Y179 HydrophobicContact CG-CD2 4.33Å; R168-Y179 VanDerWaalsContact O-CD2 3.29Å; R168-Y179 WeakPolarHBondContact O-CD2 3.46Å; R168-Y179 PolarHBondContact O-N 3.35Å; R168-T183 HydrophobicContact CG-CG2 4.49Å; R168-T183 PolarHBondContact NH2-OG1 3.32Å
169	T	89.3	Confident	88	Confident	37 Å²	37	61.7 Å²	61.7	23%	0.227	31%	0.312	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-79.3	149.8	163.5	52.5	0	0	0	0	110	W94 D98 C101 T176 T177	W94-T169 HydrophobicContact CG-CG2 4.37Å; D98-T169 HydrophobicContact CB-CG2 4.42Å; D98-T169 WeakPolarHBondContact CB-OG1 3.46Å; D98-T169 PolarHBondContact OD1-N 3.19Å; D98-T169 PolarHBondContact OD1-OG1 3.44Å; C101-T169 HydrophobicContact CB-CG2 3.72Å; T169-T176 HydrophobicContact CG2-CG2 4.08Å; T169-T177 CarbonylContact C-O 3.53Å; T169-T177 VanDerWaalsContact CA-O 3.3Å; T169-T177 WeakPolarHBondContact CA-O 3.39Å
170	G	84.7	Confident	87.1	Confident	11 Å²	11	60.6 Å²	60.6	11%	0.113	30%	0.302	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-161.3	157.4	168.3	0	0	0	0	0	113.2	T177	G170-T177 PolarHBondContact N-O 3.47Å; G170-T177 PolarHBondContact O-N 2.91Å
171	P	82.2	Confident	86.3	Confident	119 Å²	119	60.7 Å²	60.7	77%	0.773	30%	0.303	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-71.1	135.9	-177	28.9	-33.6	0	0	0	110.8	L175	P171-L175 CarbonylContact C-O 3.16Å
172	K	77.4	Confident	85.6	Confident	95 Å²	95	58 Å²	58	41%	0.413	28%	0.284	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-145.2	106.2	172.8	-173.5	166.4	-175	159.8	0	109.8	N174 L175	K172-N174 PolarHBondContact O-N 3.01Å; K172-L175 PolarHBondContact N-O 3.29Å; K172-L175 PolarHBondContact O-N 3.32Å; K172-L175 VanDerWaalsContact O-N 3.08Å
173	R	71.9	Confident	84.8	Confident	216 Å²	216	57.1 Å²	57.1	82%	0.815	28%	0.278	S	S	*	.	T	Hydrogen-bonded Turn	trans	47.4	58.9	177.6	-60.7	-175.6	179.9	175.5	-0.2	112.6	L175	R173-L175 PolarHBondContact O-N 2.78Å
174	N	77.9	Confident	84	Confident	174 Å²	174	62.4 Å²	62.4	93%	0.93	30%	0.303	S	S	*	.	T	Hydrogen-bonded Turn	trans	66.6	7	-178.9	-54.7	-21.6	0	0	0	116.3	K172	K172-N174 PolarHBondContact O-N 3.01Å
175	L	84.6	Confident	83.3	Confident	68 Å²	68	66 Å²	66	36%	0.356	32%	0.322	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.2	157.2	172.7	-56.1	177.4	0	0	0	110.7	N93 P171 K172 R173	N93-L175 HydrophobicContact CB-CB 4.3Å; N93-L175 HydrophobicContact CB-CD2 4Å; P171-L175 CarbonylContact C-O 3.16Å; K172-L175 PolarHBondContact N-O 3.29Å; K172-L175 PolarHBondContact O-N 3.32Å; K172-L175 VanDerWaalsContact O-N 3.08Å; R173-L175 PolarHBondContact O-N 2.78Å
176	T	87.5	Confident	83.1	Confident	56 Å²	56	62.1 Å²	62.1	34%	0.344	31%	0.309	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-95.8	115.3	171.4	-60.2	0	0	0	0	108.9	N93 W94 T169	N93-T176 CarbonylContact C-O 3.5Å; N93-T176 WeakPolarHBondContact CA-O 3.38Å; N93-T176 PolarHBondContact OD1-N 3.21Å; W94-T176 WeakPolarHBondContact CB-O 3.34Å; W94-T176 PolarHBondContact N-O 2.98Å; W94-T176 WeakPolarHBondContact O-CB 3.32Å; T169-T176 HydrophobicContact CG2-CG2 4.08Å
177	T	87.6	Confident	82.9	Confident	15 Å²	15	60.4 Å²	60.4	9%	0.092	30%	0.302	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-94.1	134.3	175.9	-65.3	0	0	0	0	109.9	T169 G170 Y179	T169-T177 CarbonylContact C-O 3.53Å; T169-T177 VanDerWaalsContact CA-O 3.3Å; T169-T177 WeakPolarHBondContact CA-O 3.39Å; G170-T177 PolarHBondContact N-O 3.47Å; G170-T177 PolarHBondContact O-N 2.91Å; T177-Y179 HydrophobicContact CG2-CD1 4.35Å; T177-Y179 HydrophobicContact CG2-CE1 4.36Å
178	C	89.9	Confident	83	Confident	1 Å²	1	63.4 Å²	63.4	1%	0.007	32%	0.322	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-87.9	104.9	165.2	173.3	0	0	0	0	109.1	Y87 W94 C101 R105 D180	Y87-C178 HydrophobicContact CE2-CB 4.49Å; W94-C178 HydrophobicContact CB-CB 3.87Å; W94-C178 HydrophobicContact CD2-CB 3.63Å; W94-C178 HydrophobicContact CE3-CB 3.78Å; W94-C178 HydrophobicContact CG-CB 3.67Å; C101-C178 WeakPolarHBondContact CA-SG 3.44Å; C101-C178 HydrophobicContact CB-CB 3.84Å; C101-C178 WeakPolarHBondContact CB-SG 3.29Å; C101-C178 WeakPolarHBondContact SG-CA 3.49Å; C101-C178 WeakPolarHBondContact SG-CB 3.41Å; C101-C178 CovalentContact SG-SG 2.03Å; C101-C178 PolarHBondContact SG-SG 2.93Å; R105-C178 PolarHBondContact NH2-O 2.68Å; C178-D180 PolarHBondContact O-N 3.36Å
179	Y	84.4	Confident	83.2	Confident	49 Å²	49	61.5 Å²	61.5	19%	0.192	32%	0.324	C	S	.	.			trans	-63.6	131.8	-177.6	-69.8	-72.7	0	0	0	110.8	R105 R168 T177 T183	R105-Y179 PolarHBondContact NE-O 3Å; R168-Y179 HydrophobicContact CG-CD2 4.33Å; R168-Y179 VanDerWaalsContact O-CD2 3.29Å; R168-Y179 WeakPolarHBondContact O-CD2 3.46Å; R168-Y179 PolarHBondContact O-N 3.35Å; T177-Y179 HydrophobicContact CG2-CD1 4.35Å; T177-Y179 HydrophobicContact CG2-CE1 4.36Å; Y179-T183 HydrophobicContact CD2-CG2 4.17Å; Y179-T183 HydrophobicContact CE2-CG2 3.87Å
180	D	76.3	Confident	83.3	Confident	21 Å²	21	59.7 Å²	59.7	11%	0.112	31%	0.313	C	S	.	.	S	Bend	trans	-82.9	-23.9	176.6	-169.3	59.1	0	0	0	112.7	R105 C178 Y282 R286	R105-D180 IonicContact CZ-OD1 2.63Å; R105-D180 IonicContact NE-OD1 3.73Å; R105-D180 IonicContact NH1-OD1 3.22Å; R105-D180 PolarHBondContact NH1-OD1 3.49Å; C178-D180 PolarHBondContact O-N 3.36Å; D180-Y282 PolarHBondContact OD2-OH 3.44Å; D180-R286 IonicContact OD1-CZ 2.7Å; D180-R286 IonicContact OD1-NE 2.85Å; D180-R286 IonicContact OD1-NH2 3.76Å; D180-R286 PolarHBondContact OD1-NH2 3.33Å; D180-R286 IonicContact OD2-CZ 2.81Å; D180-R286 VanDerWaalsContact OD2-CZ 3.31Å; D180-R286 IonicContact OD2-NE 3.19Å; D180-R286 PolarHBondContact OD2-NE 3.39Å; D180-R286 IonicContact OD2-NH2 3.31Å; D180-R286 PolarHBondContact OD2-NH2 2.94Å
181	T	80.3	Confident	83.7	Confident	5 Å²	5	60.8 Å²	60.8	3%	0.031	31%	0.314	C	S	.	.	S	Bend	trans	-115.4	-87.8	174.8	63.1	0	0	0	0	109.8	Y190 M260 R263	T181-Y190 HydrophobicContact CG2-CD1 4.26Å; T181-Y190 HydrophobicContact CG2-CE1 3.57Å; T181-M260 HydrophobicContact CG2-CG 4.34Å; T181-M260 HydrophobicContact CG2-SD 4.19Å; T181-R263 PolarHBondContact OG1-NH1 3.01Å
182	T	82.3	Confident	84.3	Confident	0 Å²	0	60.6 Å²	60.6	0%	0	31%	0.306	C	S	.	.			trans	-168	176	177	-172.3	0	0	0	0	109.4	Y166 E186 L187 Y190 R263	Y166-T182 HydrophobicContact CD1-CG2 4.44Å; Y166-T182 WeakPolarHBondContact O-CB 3.22Å; Y166-T182 PolarHBondContact O-OG1 2.97Å; T182-E186 HydrophobicContact CG2-CB 3.85Å; T182-E186 VanDerWaalsContact OG1-CB 3.29Å; T182-E186 WeakPolarHBondContact OG1-CB 3.31Å; T182-L187 HydrophobicContact CG2-CB 4.38Å; T182-L187 HydrophobicContact CG2-CD1 4.19Å; T182-Y190 HydrophobicContact CG2-CD1 4.23Å; T182-Y190 HydrophobicContact CG2-CG 3.88Å; T182-R263 PolarHBondContact O-NH2 3.28Å; T182-R263 VanDerWaalsContact O-NH2 3.16Å
183	T	78.1	Confident	85.1	Confident	26 Å²	26	57.6 Å²	57.6	16%	0.16	29%	0.292	C	S	.	.			trans	-68.8	166.2	170.9	60.9	0	0	0	0	111.1	R168 Y179 D185 E186 L187	R168-T183 HydrophobicContact CG-CG2 4.49Å; R168-T183 PolarHBondContact NH2-OG1 3.32Å; Y179-T183 HydrophobicContact CD2-CG2 4.17Å; Y179-T183 HydrophobicContact CE2-CG2 3.87Å; T183-D185 VanDerWaalsContact C-N 3.29Å; T183-D185 PolarHBondContact O-N 3.38Å; T183-E186 PolarHBondContact O-N 2.8Å; T183-L187 PolarHBondContact O-N 3.19Å
184	E	77	Confident	86.2	Confident	110 Å²	110	47.3 Å²	47.3	51%	0.514	25%	0.254	S	S	.	.	G	3₁₀ helix	trans	-60.3	-36.4	-175.2	-59	-54.7	140.3	0	0	112.9	E186 L187 R263	E184-E186 VanDerWaalsContact C-N 3.32Å; E184-E186 PolarHBondContact O-N 3.03Å; E184-L187 VanDerWaalsContact O-CB 3.28Å; E184-L187 WeakPolarHBondContact O-CB 3.49Å; E184-L187 PolarHBondContact O-N 3.39Å; E184-L187 WeakPolarHBondContact OE2-CD2 3.34Å; E184-R263 IonicContact OE1-CZ 2.91Å; E184-R263 IonicContact OE1-NE 2.74Å; E184-R263 PolarHBondContact OE1-NE 3.5Å; E184-R263 IonicContact OE1-NH2 3.46Å; E184-R263 PolarHBondContact OE1-NH2 2.94Å; E184-R263 IonicContact OE2-NE 3.75Å; E184-R263 IonicContact OE2-NH2 3.94Å
185	D	79.2	Confident	87	Confident	141 Å²	141	42.2 Å²	42.2	75%	0.754	23%	0.225	S	C	*	.	G	3₁₀ helix	trans	-64.1	-33.7	-177	-46.3	-51.9	0	0	0	113.6	T183	T183-D185 VanDerWaalsContact C-N 3.29Å; T183-D185 PolarHBondContact O-N 3.38Å
186	E	86.8	Confident	87.5	Confident	54 Å²	54	42.1 Å²	42.1	25%	0.252	23%	0.227	S	C	.	.	G	3₁₀ helix	trans	-97.5	-2.3	-177.9	-65.8	-65.9	165.2	0	0	112.3	Y166 T182 T183 E184 P188 G189 Y190	Y166-E186 HydrophobicContact CD1-CB 4.15Å; Y166-E186 HydrophobicContact CE1-CB 4.2Å; T182-E186 HydrophobicContact CG2-CB 3.85Å; T182-E186 VanDerWaalsContact OG1-CB 3.29Å; T182-E186 WeakPolarHBondContact OG1-CB 3.31Å; T183-E186 PolarHBondContact O-N 2.8Å; E184-E186 VanDerWaalsContact C-N 3.32Å; E184-E186 PolarHBondContact O-N 3.03Å; E186-P188 VanDerWaalsContact C-CD 3.49Å; E186-G189 PolarHBondContact O-N 3.49Å; E186-Y190 WeakPolarHBondContact O-CB 3.37Å; E186-Y190 PolarHBondContact O-N 3.36Å
187	L	85.9	Confident	87.9	Confident	0 Å²	0	40.1 Å²	40.1	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-61.5	-37.9	-173.6	-169.2	65	0	0	0	113.4	T182 T183 E184 Y190 F191 M260 R263 L264	T182-L187 HydrophobicContact CG2-CB 4.38Å; T182-L187 HydrophobicContact CG2-CD1 4.19Å; T183-L187 PolarHBondContact O-N 3.19Å; E184-L187 VanDerWaalsContact O-CB 3.28Å; E184-L187 WeakPolarHBondContact O-CB 3.49Å; E184-L187 PolarHBondContact O-N 3.39Å; E184-L187 WeakPolarHBondContact OE2-CD2 3.34Å; L187-Y190 PolarHBondContact O-N 2.87Å; L187-F191 WeakPolarHBondContact O-CB 3.29Å; L187-F191 PolarHBondContact O-N 2.76Å; L187-M260 HydrophobicContact CD1-CE 4.17Å; L187-M260 HydrophobicContact CD1-CG 4.49Å; L187-R263 HydrophobicContact CD2-CB 3.58Å; L187-L264 HydrophobicContact CB-CD2 3.97Å; L187-L264 HydrophobicContact CD2-CD2 3.76Å; L187-L264 HydrophobicContact CD2-CG 3.76Å; L187-L264 HydrophobicContact CG-CD1 4.33Å; L187-L264 HydrophobicContact CG-CD2 3.78Å; L187-L264 HydrophobicContact CG-CG 3.89Å
188	P	91.2	Very high	88.2	Confident	64 Å²	64	40.1 Å²	40.1	42%	0.416	21%	0.214	S	C	.	.	H	α-helix	trans	-61.7	-45.8	175	-23.1	33.8	0	0	0	112.9	E186 F191 I192 L264	E186-P188 VanDerWaalsContact C-CD 3.49Å; P188-F191 WeakPolarHBondContact O-CB 3.38Å; P188-F191 PolarHBondContact O-N 2.89Å; P188-I192 PolarHBondContact O-N 3.26Å; P188-L264 HydrophobicContact CG-CD2 3.84Å
189	G	92.1	Very high	88.4	Confident	29 Å²	29	43.4 Å²	43.4	30%	0.299	23%	0.234	S	C	.	.	H	α-helix	trans	-64.6	-44.3	177.4	0	0	0	0	0	111.9	E186 F191 I192 Y193	E186-G189 PolarHBondContact O-N 3.49Å; G189-F191 VanDerWaalsContact C-N 3.26Å; G189-F191 PolarHBondContact O-N 3.07Å; G189-I192 PolarHBondContact O-N 3.45Å; G189-Y193 PolarHBondContact O-N 3.16Å
190	Y	92.4	Very high	88.9	Confident	0 Å²	0	47.8 Å²	47.8	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-64	-30.6	175.4	-172.7	-101.6	0	0	0	112.5	Y166 T181 T182 E186 L187 Y193 S194 K256 M260	Y166-Y190 HydrophobicContact CD1-CD2 4.04Å; Y166-Y190 HydrophobicContact CD1-CG 4.46Å; Y166-Y190 AromaticContact CD2-CD2 3.6Å; Y166-Y190 HydrophobicContact CD2-CD2 3.6Å; Y166-Y190 HydrophobicContact CD2-CE2 4.27Å; Y166-Y190 HydrophobicContact CE2-CD2 4.2Å; Y166-Y190 AromaticContact CG-CD2 3.5Å; Y166-Y190 HydrophobicContact CG-CD2 3.5Å; Y166-Y190 VanDerWaalsContact CG-CD2 3.5Å; Y166-Y190 HydrophobicContact CG-CE2 4.27Å; Y166-Y190 HydrophobicContact CG-CG 4.34Å; T181-Y190 HydrophobicContact CG2-CD1 4.26Å; T181-Y190 HydrophobicContact CG2-CE1 3.57Å; T182-Y190 HydrophobicContact CG2-CD1 4.23Å; T182-Y190 HydrophobicContact CG2-CG 3.88Å; E186-Y190 WeakPolarHBondContact O-CB 3.37Å; E186-Y190 PolarHBondContact O-N 3.36Å; L187-Y190 PolarHBondContact O-N 2.87Å; Y190-Y193 AromaticContact CD2-CD1 3.84Å; Y190-Y193 HydrophobicContact CD2-CD1 3.84Å; Y190-Y193 HydrophobicContact CD2-CE1 4.4Å; Y190-Y193 AromaticContact CE2-CD1 3.84Å; Y190-Y193 HydrophobicContact CE2-CD1 3.84Å; Y190-Y193 HydrophobicContact CE2-CE1 4Å; Y190-S194 VanDerWaalsContact O-CB 3.23Å; Y190-S194 WeakPolarHBondContact O-CB 3.41Å; Y190-S194 PolarHBondContact O-N 3.47Å; Y190-K256 PolarHBondContact OH-NZ 3.41Å; Y190-M260 HydrophobicContact CD1-CE 3.23Å; Y190-M260 HydrophobicContact CD1-SD 3.89Å; Y190-M260 HydrophobicContact CE1-CE 3.74Å; Y190-M260 HydrophobicContact CE1-SD 3.73Å; Y190-M260 HydrophobicContact CG-CE 4.24Å
191	F	93.3	Very high	89.7	Confident	33 Å²	33	47.4 Å²	47.4	15%	0.145	26%	0.256	C	S	.	.	H	α-helix	trans	-66.6	-45.7	174.8	178.2	-102.5	0	0	0	112.8	L187 P188 G189 Y193 S194 M195 M260 R261 L264	L187-F191 WeakPolarHBondContact O-CB 3.29Å; L187-F191 PolarHBondContact O-N 2.76Å; P188-F191 WeakPolarHBondContact O-CB 3.38Å; P188-F191 PolarHBondContact O-N 2.89Å; G189-F191 VanDerWaalsContact C-N 3.26Å; G189-F191 PolarHBondContact O-N 3.07Å; F191-Y193 VanDerWaalsContact C-N 3.33Å; F191-Y193 PolarHBondContact O-N 3.29Å; F191-S194 PolarHBondContact O-N 2.94Å; F191-M195 HydrophobicContact CD2-CE 4.41Å; F191-M195 HydrophobicContact CE1-CE 4.44Å; F191-M195 HydrophobicContact CE1-CG 4.19Å; F191-M195 HydrophobicContact CE2-CE 3.43Å; F191-M195 VanDerWaalsContact CE2-CE 3.43Å; F191-M195 HydrophobicContact CE2-CG 4.24Å; F191-M195 HydrophobicContact CZ-CE 3.45Å; F191-M195 VanDerWaalsContact CZ-CE 3.45Å; F191-M195 HydrophobicContact CZ-CG 4.04Å; F191-M195 WeakPolarHBondContact O-CB 3.5Å; F191-M195 WeakPolarHBondContact O-CG 3.38Å; F191-M195 PolarHBondContact O-N 3.19Å; F191-M260 HydrophobicContact CB-CE 3.68Å; F191-M260 HydrophobicContact CD2-CB 3.88Å; F191-M260 HydrophobicContact CD2-CE 4.06Å; F191-M260 HydrophobicContact CG-CE 4.38Å; F191-R261 HydrophobicContact CE2-CB 4.28Å; F191-L264 HydrophobicContact CB-CD1 3.7Å; F191-L264 HydrophobicContact CD1-CD1 4.26Å; F191-L264 HydrophobicContact CD2-CD1 4.23Å; F191-L264 HydrophobicContact CG-CD1 3.82Å
192	I	94.3	Very high	90.3	Very high	116 Å²	116	47.4 Å²	47.4	60%	0.595	26%	0.255	S	S	*	.	H	α-helix	trans	-60.4	-47.3	174.7	-62.9	168.7	0	0	0	109.8	P188 G189 S194 M195 T196	P188-I192 PolarHBondContact O-N 3.26Å; G189-I192 PolarHBondContact O-N 3.45Å; I192-S194 PolarHBondContact O-N 3.33Å; I192-M195 PolarHBondContact O-N 3.46Å; I192-T196 PolarHBondContact O-N 3.29Å; I192-T196 PolarHBondContact O-OG1 3Å; I192-T196 VanDerWaalsContact O-OG1 3.09Å
193	Y	95	Very high	90.9	Very high	32 Å²	32	49.7 Å²	49.7	13%	0.125	27%	0.271	C	S	.	.	H	α-helix	trans	-57.5	-47.8	175.5	168.7	-113.4	0	0	0	112.7	S159 P162 I163 Y166 G189 Y190 F191 M195 T196 L197	S159-Y193 WeakPolarHBondContact O-CE2 3.14Å; S159-Y193 PolarHBondContact O-OH 3.45Å; P162-Y193 HydrophobicContact CB-CE1 4.36Å; P162-Y193 HydrophobicContact CB-CE2 4.03Å; P162-Y193 HydrophobicContact CG-CE2 3.85Å; I163-Y193 HydrophobicContact CG1-CE1 3.96Å; I163-Y193 WeakPolarHBondContact CG1-OH 3.33Å; Y166-Y193 HydrophobicContact CD2-CD1 4.41Å; Y166-Y193 HydrophobicContact CE2-CD1 4.32Å; Y166-Y193 HydrophobicContact CE2-CG 4.48Å; G189-Y193 PolarHBondContact O-N 3.16Å; Y190-Y193 AromaticContact CD2-CD1 3.84Å; Y190-Y193 HydrophobicContact CD2-CD1 3.84Å; Y190-Y193 HydrophobicContact CD2-CE1 4.4Å; Y190-Y193 AromaticContact CE2-CD1 3.84Å; Y190-Y193 HydrophobicContact CE2-CD1 3.84Å; Y190-Y193 HydrophobicContact CE2-CE1 4Å; F191-Y193 VanDerWaalsContact C-N 3.33Å; F191-Y193 PolarHBondContact O-N 3.29Å; Y193-M195 VanDerWaalsContact C-N 3.32Å; Y193-M195 PolarHBondContact O-N 3.3Å; Y193-T196 PolarHBondContact O-N 2.85Å; Y193-L197 HydrophobicContact CD1-CD1 4.38Å; Y193-L197 HydrophobicContact CD2-CD1 4.43Å; Y193-L197 HydrophobicContact CD2-CG 4.27Å; Y193-L197 HydrophobicContact CE1-CD1 3.68Å; Y193-L197 HydrophobicContact CE1-CG 4.5Å; Y193-L197 HydrophobicContact CE2-CD1 3.74Å; Y193-L197 HydrophobicContact CE2-CD2 4.15Å; Y193-L197 HydrophobicContact CE2-CG 3.82Å; Y193-L197 WeakPolarHBondContact O-CG 3.26Å; Y193-L197 PolarHBondContact O-N 3.29Å; Y193-L197 WeakPolarHBondContact OH-CD1 3.44Å
194	S	94.4	Very high	91.7	Very high	0 Å²	0	51.5 Å²	51.5	0%	0	28%	0.281	C	S	.	.	H	α-helix	trans	-61.3	-38.8	177.8	-178.4	0	0	0	0	112.1	Y190 F191 I192 L197 T198 K256 N257	Y190-S194 VanDerWaalsContact O-CB 3.23Å; Y190-S194 WeakPolarHBondContact O-CB 3.41Å; Y190-S194 PolarHBondContact O-N 3.47Å; F191-S194 PolarHBondContact O-N 2.94Å; I192-S194 PolarHBondContact O-N 3.33Å; S194-L197 PolarHBondContact O-N 3.39Å; S194-T198 WeakPolarHBondContact O-CB 3.21Å; S194-T198 PolarHBondContact O-N 2.88Å; S194-T198 PolarHBondContact O-OG1 3.28Å; S194-K256 WeakPolarHBondContact OG-CE 3.36Å; S194-N257 PolarHBondContact OG-OD1 3.09Å; S194-N257 VanDerWaalsContact OG-OD1 3.04Å
195	M	94.7	Very high	92.5	Very high	67 Å²	67	46.5 Å²	46.5	33%	0.33	26%	0.258	S	S	.	.	H	α-helix	trans	-66.3	-45.9	175.8	-79	-64	172.9	0	0	111.9	F191 I192 Y193 L197 T198 V199 N257	F191-M195 HydrophobicContact CD2-CE 4.41Å; F191-M195 HydrophobicContact CE1-CE 4.44Å; F191-M195 HydrophobicContact CE1-CG 4.19Å; F191-M195 HydrophobicContact CE2-CE 3.43Å; F191-M195 VanDerWaalsContact CE2-CE 3.43Å; F191-M195 HydrophobicContact CE2-CG 4.24Å; F191-M195 HydrophobicContact CZ-CE 3.45Å; F191-M195 VanDerWaalsContact CZ-CE 3.45Å; F191-M195 HydrophobicContact CZ-CG 4.04Å; F191-M195 WeakPolarHBondContact O-CB 3.5Å; F191-M195 WeakPolarHBondContact O-CG 3.38Å; F191-M195 PolarHBondContact O-N 3.19Å; I192-M195 PolarHBondContact O-N 3.46Å; Y193-M195 VanDerWaalsContact C-N 3.32Å; Y193-M195 PolarHBondContact O-N 3.3Å; M195-L197 VanDerWaalsContact C-N 3.31Å; M195-L197 PolarHBondContact O-N 2.84Å; M195-T198 WeakPolarHBondContact O-CB 3.2Å; M195-T198 PolarHBondContact O-N 3.16Å; M195-V199 WeakPolarHBondContact O-CG2 3.25Å; M195-V199 PolarHBondContact O-N 2.84Å; M195-N257 HydrophobicContact CE-CB 3.47Å; M195-N257 VanDerWaalsContact CE-CB 3.47Å; M195-N257 WeakPolarHBondContact CE-OD1 3.39Å; M195-N257 HydrophobicContact SD-CB 4.47Å
196	T	95.6	Very high	93.1	Very high	66 Å²	66	42.7 Å²	42.7	41%	0.405	24%	0.235	S	C	.	.	H	α-helix	trans	-55.6	-47.6	174	-60.9	0	0	0	0	110.8	I192 Y193 T198 V199 F200	I192-T196 PolarHBondContact O-N 3.29Å; I192-T196 PolarHBondContact O-OG1 3Å; I192-T196 VanDerWaalsContact O-OG1 3.09Å; Y193-T196 PolarHBondContact O-N 2.85Å; T196-T198 VanDerWaalsContact C-N 3.32Å; T196-T198 PolarHBondContact O-N 2.85Å; T196-V199 PolarHBondContact O-N 2.89Å; T196-F200 HydrophobicContact CG2-CD2 3.72Å; T196-F200 HydrophobicContact CG2-CE2 4.06Å; T196-F200 VanDerWaalsContact O-CD2 3.29Å; T196-F200 WeakPolarHBondContact O-CD2 3.31Å; T196-F200 PolarHBondContact O-N 3.43Å
197	L	95	Very high	93.3	Very high	14 Å²	14	44.7 Å²	44.7	7%	0.073	25%	0.247	C	C	.	.	H	α-helix	trans	-64.4	-35.3	175.7	-71.1	-173	0	0	0	113.3	Y113 M160 Y193 S194 M195 G201 F202	Y113-L197 HydrophobicContact CE1-CB 4.35Å; Y113-L197 HydrophobicContact CE2-CB 4.45Å; Y113-L197 HydrophobicContact CE2-CD1 4Å; Y113-L197 WeakPolarHBondContact OH-CB 3.3Å; M160-L197 HydrophobicContact CE-CD1 3.62Å; M160-L197 HydrophobicContact CE-CD2 3.47Å; M160-L197 VanDerWaalsContact CE-CD2 3.47Å; M160-L197 HydrophobicContact CE-CG 4.16Å; M160-L197 HydrophobicContact SD-CD1 3.98Å; Y193-L197 HydrophobicContact CD1-CD1 4.38Å; Y193-L197 HydrophobicContact CD2-CD1 4.43Å; Y193-L197 HydrophobicContact CD2-CG 4.27Å; Y193-L197 HydrophobicContact CE1-CD1 3.68Å; Y193-L197 HydrophobicContact CE1-CG 4.5Å; Y193-L197 HydrophobicContact CE2-CD1 3.74Å; Y193-L197 HydrophobicContact CE2-CD2 4.15Å; Y193-L197 HydrophobicContact CE2-CG 3.82Å; Y193-L197 WeakPolarHBondContact O-CG 3.26Å; Y193-L197 PolarHBondContact O-N 3.29Å; Y193-L197 WeakPolarHBondContact OH-CD1 3.44Å; S194-L197 PolarHBondContact O-N 3.39Å; M195-L197 VanDerWaalsContact C-N 3.31Å; M195-L197 PolarHBondContact O-N 2.84Å; L197-G201 CarbonylContact O-C 3.57Å; L197-G201 WeakPolarHBondContact O-CA 3.42Å; L197-G201 PolarHBondContact O-N 3.43Å; L197-F202 PolarHBondContact O-N 3.03Å
198	T	94.3	Very high	93.7	Very high	15 Å²	15	47.9 Å²	47.9	9%	0.092	26%	0.263	C	S	.	.	H	α-helix	trans	-66	-43.3	177	-60.2	0	0	0	0	110.9	S194 M195 T196 F202 C203 H253 N257	S194-T198 WeakPolarHBondContact O-CB 3.21Å; S194-T198 PolarHBondContact O-N 2.88Å; S194-T198 PolarHBondContact O-OG1 3.28Å; M195-T198 WeakPolarHBondContact O-CB 3.2Å; M195-T198 PolarHBondContact O-N 3.16Å; T196-T198 VanDerWaalsContact C-N 3.32Å; T196-T198 PolarHBondContact O-N 2.85Å; T198-F202 HydrophobicContact CG2-CD1 4.48Å; T198-F202 WeakPolarHBondContact O-CA 3.39Å; T198-F202 VanDerWaalsContact O-CB 3.32Å; T198-F202 WeakPolarHBondContact O-CB 3.25Å; T198-F202 PolarHBondContact O-N 2.87Å; T198-C203 PolarHBondContact O-N 2.9Å; T198-C203 PolarHBondContact O-SG 2.96Å; T198-C203 VanDerWaalsContact O-SG 3.4Å; T198-H253 HydrophobicContact CG2-CB 4.16Å; T198-N257 PolarHBondContact OG1-ND2 2.64Å
199	V	94.6	Very high	93.6	Very high	69 Å²	69	44.9 Å²	44.9	42%	0.418	24%	0.243	S	C	.	.	I	π-helix	trans	-68.8	-56.7	179.4	173.9	0	0	0	0	111	M195 T196 C203 V204	M195-V199 WeakPolarHBondContact O-CG2 3.25Å; M195-V199 PolarHBondContact O-N 2.84Å; T196-V199 PolarHBondContact O-N 2.89Å; V199-C203 WeakPolarHBondContact O-CB 3.36Å; V199-C203 PolarHBondContact O-N 3.29Å; V199-V204 PolarHBondContact O-N 3.21Å
200	F	94.9	Very high	93.4	Very high	142 Å²	142	49.4 Å²	49.4	62%	0.623	26%	0.255	S	S	*	.	I	π-helix	trans	-84.2	-35.4	-172	-65.6	-72	0	0	0	113.3	T196 P205	T196-F200 HydrophobicContact CG2-CD2 3.72Å; T196-F200 HydrophobicContact CG2-CE2 4.06Å; T196-F200 VanDerWaalsContact O-CD2 3.29Å; T196-F200 WeakPolarHBondContact O-CD2 3.31Å; T196-F200 PolarHBondContact O-N 3.43Å; F200-P205 WeakPolarHBondContact O-CD 3.4Å
201	G	92.3	Very high	93.4	Very high	13 Å²	13	52.7 Å²	52.7	13%	0.134	28%	0.278	C	S	.	.	I	π-helix	trans	-87.5	-16	-178.2	0	0	0	0	0	114.2	Y113 I116 L197	Y113-G201 WeakPolarHBondContact CD1-O 3.23Å; I116-G201 WeakPolarHBondContact CG2-O 3.41Å; L197-G201 CarbonylContact O-C 3.57Å; L197-G201 WeakPolarHBondContact O-CA 3.42Å; L197-G201 PolarHBondContact O-N 3.43Å
202	F	93.6	Very high	93.1	Very high	5 Å²	5	51.8 Å²	51.8	2%	0.022	28%	0.275	C	S	.	.	I	π-helix	trans	-128.3	-58.3	179.5	168.8	-99	0	0	0	113.8	I116 L197 T198 V204 P205 F206 F245 L250 H253	I116-F202 HydrophobicContact CD1-CD2 4.12Å; L197-F202 PolarHBondContact O-N 3.03Å; T198-F202 HydrophobicContact CG2-CD1 4.48Å; T198-F202 WeakPolarHBondContact O-CA 3.39Å; T198-F202 VanDerWaalsContact O-CB 3.32Å; T198-F202 WeakPolarHBondContact O-CB 3.25Å; T198-F202 PolarHBondContact O-N 2.87Å; F202-V204 PolarHBondContact O-N 2.75Å; F202-P205 WeakPolarHBondContact O-CD 3.22Å; F202-F206 VanDerWaalsContact O-CB 3.23Å; F202-F206 WeakPolarHBondContact O-CB 3.21Å; F202-F206 PolarHBondContact O-N 2.86Å; F202-F245 HydrophobicContact CD2-CD1 4.35Å; F202-F245 HydrophobicContact CD2-CE1 4.17Å; F202-F245 AromaticContact CE2-CD1 3.69Å; F202-F245 HydrophobicContact CE2-CD1 3.69Å; F202-F245 AromaticContact CE2-CE1 3.97Å; F202-F245 HydrophobicContact CE2-CE1 3.97Å; F202-L250 HydrophobicContact CE1-CD1 3.83Å; F202-L250 HydrophobicContact CZ-CB 3.84Å; F202-L250 HydrophobicContact CZ-CD1 3.8Å; F202-L250 HydrophobicContact CZ-CG 4.45Å; F202-H253 WeakPolarHBondContact CB-NE2 3.18Å; F202-H253 HydrophobicContact CD1-CB 4.15Å; F202-H253 AromaticContact CD1-CG 3.92Å; F202-H253 AromaticContact CD2-CE1 3.73Å; F202-H253 AromaticContact CD2-ND1 3.68Å; F202-H253 HydrophobicContact CE1-CB 4.36Å; F202-H253 AromaticContact CG-CD2 3.89Å; F202-H253 AromaticContact CG-CE1 3.77Å; F202-H253 AromaticContact CG-CG 3.8Å; F202-H253 AromaticContact CG-ND1 3.72Å; F202-H253 AromaticContact CG-NE2 3.89Å
203	C	93.9	Very high	92.7	Very high	48 Å²	48	46.5 Å²	46.5	32%	0.324	25%	0.247	S	C	.	.	I	π-helix	trans	-62.3	-46.1	-174	-63.6	0	0	0	0	112.5	T198 V199 F206 I207	T198-C203 PolarHBondContact O-N 2.9Å; T198-C203 PolarHBondContact O-SG 2.96Å; T198-C203 VanDerWaalsContact O-SG 3.4Å; V199-C203 WeakPolarHBondContact O-CB 3.36Å; V199-C203 PolarHBondContact O-N 3.29Å; C203-F206 PolarHBondContact O-N 3.5Å; C203-I207 VanDerWaalsContact O-CG1 3.3Å; C203-I207 WeakPolarHBondContact O-CG1 3.15Å; C203-I207 PolarHBondContact O-N 2.96Å
204	V	95.3	Very high	92.2	Very high	64 Å²	64	47 Å²	47	39%	0.388	26%	0.263	S	S	.	.	H	α-helix	trans	-61.2	-53.4	177.6	169	0	0	0	0	111.4	V199 F202 F206 I207 I208	V199-V204 PolarHBondContact O-N 3.21Å; F202-V204 PolarHBondContact O-N 2.75Å; V204-F206 VanDerWaalsContact C-N 3.31Å; V204-F206 PolarHBondContact O-N 3.31Å; V204-I207 PolarHBondContact O-N 2.9Å; V204-I208 HydrophobicContact CG1-CD1 3.94Å; V204-I208 WeakPolarHBondContact O-CG1 3.34Å; V204-I208 PolarHBondContact O-N 2.92Å
205	P	93.6	Very high	91.9	Very high	5 Å²	5	50.9 Å²	50.9	3%	0.032	28%	0.282	C	S	.	.	H	α-helix	trans	-52.2	-44.7	171.7	-34	39.2	0	0	0	114.3	I116 L117 T120 F200 F202 I207 I208 I209	I116-P205 HydrophobicContact CG2-CB 3.39Å; I116-P205 HydrophobicContact CG2-CG 3.85Å; L117-P205 HydrophobicContact CD2-CG 3.92Å; T120-P205 WeakPolarHBondContact OG1-CB 3.31Å; F200-P205 WeakPolarHBondContact O-CD 3.4Å; F202-P205 WeakPolarHBondContact O-CD 3.22Å; P205-I207 PolarHBondContact O-N 3.42Å; P205-I208 PolarHBondContact O-N 2.88Å; P205-I209 VanDerWaalsContact O-CG1 3.3Å; P205-I209 WeakPolarHBondContact O-CG1 3.48Å; P205-I209 PolarHBondContact O-N 2.83Å
206	F	90.9	Very high	91.3	Very high	60 Å²	60	47.7 Å²	47.7	26%	0.263	27%	0.266	S	S	.	.	H	α-helix	trans	-61.1	-45.9	179.9	177.3	-108.5	0	0	0	112.1	F202 C203 V204 I208 I209 F210 F245	F202-F206 VanDerWaalsContact O-CB 3.23Å; F202-F206 WeakPolarHBondContact O-CB 3.21Å; F202-F206 PolarHBondContact O-N 2.86Å; C203-F206 PolarHBondContact O-N 3.5Å; V204-F206 VanDerWaalsContact C-N 3.31Å; V204-F206 PolarHBondContact O-N 3.31Å; F206-I208 PolarHBondContact O-N 2.85Å; F206-I209 PolarHBondContact O-N 3.44Å; F206-F210 WeakPolarHBondContact O-CB 3.46Å; F206-F210 PolarHBondContact O-N 2.99Å; F206-F245 HydrophobicContact CB-CD1 4.24Å; F206-F245 HydrophobicContact CB-CE1 4.18Å; F206-F245 HydrophobicContact CD2-CB 4Å; F206-F245 AromaticContact CD2-CD1 3.42Å; F206-F245 HydrophobicContact CD2-CD1 3.42Å; F206-F245 VanDerWaalsContact CD2-CD1 3.42Å; F206-F245 HydrophobicContact CD2-CE1 4.13Å; F206-F245 AromaticContact CD2-CG 3.89Å; F206-F245 HydrophobicContact CD2-CG 3.89Å; F206-F245 HydrophobicContact CE2-CB 3.93Å; F206-F245 HydrophobicContact CE2-CD1 4.21Å; F206-F245 HydrophobicContact CE2-CG 4.32Å; F206-F245 HydrophobicContact CG-CD1 4.25Å
207	I	92.6	Very high	90.7	Very high	97 Å²	97	47.4 Å²	47.4	50%	0.497	26%	0.264	S	S	.	.	H	α-helix	trans	-61.5	-44.6	175.9	-68	165.2	0	0	0	110.5	C203 V204 P205 I209 F210 C211	C203-I207 VanDerWaalsContact O-CG1 3.3Å; C203-I207 WeakPolarHBondContact O-CG1 3.15Å; C203-I207 PolarHBondContact O-N 2.96Å; V204-I207 PolarHBondContact O-N 2.9Å; P205-I207 PolarHBondContact O-N 3.42Å; I207-I209 VanDerWaalsContact C-N 3.34Å; I207-I209 PolarHBondContact O-N 2.99Å; I207-F210 PolarHBondContact O-N 3.34Å; I207-C211 WeakPolarHBondContact O-CB 3.13Å; I207-C211 PolarHBondContact O-N 3.45Å; I207-C211 PolarHBondContact O-SG 2.9Å
208	I	93.4	Very high	90.1	Very high	67 Å²	67	53.5 Å²	53.5	34%	0.344	29%	0.29	S	S	.	.	H	α-helix	trans	-58.7	-47.4	177.7	-67.5	166.9	0	0	0	110.7	T120 V124 V204 P205 F206 C212	T120-I208 HydrophobicContact CG2-CB 4.16Å; T120-I208 HydrophobicContact CG2-CD1 4.45Å; T120-I208 HydrophobicContact CG2-CG2 3.74Å; V124-I208 HydrophobicContact CG2-CG2 3.76Å; V204-I208 HydrophobicContact CG1-CD1 3.94Å; V204-I208 WeakPolarHBondContact O-CG1 3.34Å; V204-I208 PolarHBondContact O-N 2.92Å; P205-I208 PolarHBondContact O-N 2.88Å; F206-I208 PolarHBondContact O-N 2.85Å; I208-C212 VanDerWaalsContact O-CB 3.3Å; I208-C212 WeakPolarHBondContact O-CB 3.4Å; I208-C212 PolarHBondContact O-N 3.34Å; I208-C212 PolarHBondContact O-SG 3.44Å
209	I	90.1	Very high	89.5	Confident	0 Å²	0	53.3 Å²	53.3	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-60.8	-48.9	178.3	-70.7	171.2	0	0	0	110.4	L119 T120 P205 F206 I207 C211 C212 Y213 V241 F245	L119-I209 HydrophobicContact CB-CD1 4.39Å; T120-I209 HydrophobicContact CG2-CG1 4.44Å; P205-I209 VanDerWaalsContact O-CG1 3.3Å; P205-I209 WeakPolarHBondContact O-CG1 3.48Å; P205-I209 PolarHBondContact O-N 2.83Å; F206-I209 PolarHBondContact O-N 3.44Å; I207-I209 VanDerWaalsContact C-N 3.34Å; I207-I209 PolarHBondContact O-N 2.99Å; I209-C211 PolarHBondContact O-N 2.68Å; I209-C212 PolarHBondContact O-N 2.88Å; I209-Y213 HydrophobicContact CG2-CD2 3.54Å; I209-Y213 HydrophobicContact CG2-CE2 3.39Å; I209-Y213 WeakPolarHBondContact O-CD2 3.35Å; I209-Y213 PolarHBondContact O-N 2.95Å; I209-V241 HydrophobicContact CG2-CG1 3.97Å; I209-F245 HydrophobicContact CD1-CD2 4.4Å; I209-F245 HydrophobicContact CD1-CE1 4.27Å; I209-F245 HydrophobicContact CD1-CE2 3.44Å; I209-F245 VanDerWaalsContact CD1-CE2 3.44Å; I209-F245 HydrophobicContact CD1-CZ 3.35Å
210	F	87.9	Confident	88.6	Confident	124 Å²	124	50.8 Å²	50.8	54%	0.544	27%	0.274	S	S	.	.	H	α-helix	trans	-58.7	-48.4	-180	-174.3	-96.7	0	0	0	111.7	F206 I207 Y213 G214 L242	F206-F210 WeakPolarHBondContact O-CB 3.46Å; F206-F210 PolarHBondContact O-N 2.99Å; I207-F210 PolarHBondContact O-N 3.34Å; F210-Y213 PolarHBondContact O-N 3.14Å; F210-G214 PolarHBondContact O-N 3.26Å; F210-L242 HydrophobicContact CD2-CD2 4.45Å
211	C	90.9	Very high	87.7	Confident	70 Å²	70	50.6 Å²	50.6	47%	0.473	28%	0.278	S	S	.	.	H	α-helix	trans	-63.5	-43.9	176.3	-68.2	0	0	0	0	112.3	I207 I209 Y213 G214 M215	I207-C211 WeakPolarHBondContact O-CB 3.13Å; I207-C211 PolarHBondContact O-N 3.45Å; I207-C211 PolarHBondContact O-SG 2.9Å; I209-C211 PolarHBondContact O-N 2.68Å; C211-Y213 VanDerWaalsContact C-N 3.31Å; C211-Y213 PolarHBondContact O-N 3.36Å; C211-G214 PolarHBondContact O-N 2.9Å; C211-M215 WeakPolarHBondContact O-CB 3.33Å; C211-M215 VanDerWaalsContact O-CG 3.25Å; C211-M215 WeakPolarHBondContact O-CG 3.43Å; C211-M215 PolarHBondContact O-N 3.5Å
212	C	88.9	Confident	87	Confident	13 Å²	13	59.4 Å²	59.4	9%	0.088	31%	0.309	C	S	.	.	H	α-helix	trans	-57.4	-46.3	177.1	-75.7	0	0	0	0	111.1	Y127 I208 I209 M215 I216	Y127-C212 HydrophobicContact CG-CB 4.44Å; I208-C212 VanDerWaalsContact O-CB 3.3Å; I208-C212 WeakPolarHBondContact O-CB 3.4Å; I208-C212 PolarHBondContact O-N 3.34Å; I208-C212 PolarHBondContact O-SG 3.44Å; I209-C212 PolarHBondContact O-N 2.88Å; C212-M215 PolarHBondContact O-N 2.68Å; C212-I216 WeakPolarHBondContact O-CD1 3.32Å; C212-I216 VanDerWaalsContact O-CG1 3.25Å; C212-I216 WeakPolarHBondContact O-CG1 3.25Å; C212-I216 PolarHBondContact O-N 3.3Å
213	Y	84.6	Confident	85.7	Confident	5 Å²	5	63 Å²	63	2%	0.02	33%	0.328	C	S	.	.	H	α-helix	trans	-73.4	-38.4	-179.2	-70.5	-33.8	0	0	0	113.4	S123 I209 F210 C211 M215 I216 V217 V238 V241 L242	S123-Y213 PolarHBondContact OG-OH 2.87Å; S123-Y213 VanDerWaalsContact OG-OH 3.07Å; I209-Y213 HydrophobicContact CG2-CD2 3.54Å; I209-Y213 HydrophobicContact CG2-CE2 3.39Å; I209-Y213 WeakPolarHBondContact O-CD2 3.35Å; I209-Y213 PolarHBondContact O-N 2.95Å; F210-Y213 PolarHBondContact O-N 3.14Å; C211-Y213 VanDerWaalsContact C-N 3.31Å; C211-Y213 PolarHBondContact O-N 3.36Å; Y213-M215 VanDerWaalsContact C-N 3.27Å; Y213-M215 PolarHBondContact O-N 3.3Å; Y213-I216 HydrophobicContact CD1-CD1 3.71Å; Y213-I216 HydrophobicContact CE1-CD1 4.2Å; Y213-I216 PolarHBondContact O-N 3.11Å; Y213-V217 WeakPolarHBondContact O-CG2 3.5Å; Y213-V217 PolarHBondContact O-N 3.39Å; Y213-V238 HydrophobicContact CD1-CB 4.11Å; Y213-V238 HydrophobicContact CD1-CG1 4.35Å; Y213-V238 HydrophobicContact CD1-CG2 3.18Å; Y213-V238 HydrophobicContact CD2-CB 4.26Å; Y213-V238 HydrophobicContact CD2-CG1 3.94Å; Y213-V238 HydrophobicContact CD2-CG2 4.19Å; Y213-V238 HydrophobicContact CE1-CB 4.38Å; Y213-V238 HydrophobicContact CE1-CG2 3.59Å; Y213-V238 HydrophobicContact CE2-CB 4.49Å; Y213-V238 HydrophobicContact CE2-CG2 4.48Å; Y213-V238 HydrophobicContact CG-CB 4.06Å; Y213-V238 HydrophobicContact CG-CG1 3.81Å; Y213-V238 HydrophobicContact CG-CG2 3.54Å; Y213-V241 HydrophobicContact CE2-CB 3.86Å; Y213-V241 HydrophobicContact CE2-CG1 3.8Å; Y213-L242 HydrophobicContact CD2-CD2 4.38Å; Y213-L242 HydrophobicContact CD2-CG 4.28Å
214	G	85.7	Confident	84	Confident	43 Å²	43	67.2 Å²	67.2	44%	0.443	35%	0.348	S	S	.	.	H	α-helix	trans	-57.2	-42.8	171.5	0	0	0	0	0	111.9	F210 C211 V217 K218	F210-G214 PolarHBondContact O-N 3.26Å; C211-G214 PolarHBondContact O-N 2.9Å; G214-V217 PolarHBondContact O-N 3.21Å; G214-K218 WeakPolarHBondContact O-CB 3.32Å; G214-K218 PolarHBondContact O-N 3.37Å
215	M	86.6	Confident	82.2	Confident	81 Å²	81	66.8 Å²	66.8	40%	0.399	34%	0.342	S	S	.	.	H	α-helix	trans	-69.2	-38.6	176.3	-69.6	-71.8	-72.7	0	0	113.2	Y127 C211 C212 Y213 K218 A219	Y127-M215 HydrophobicContact CD2-CB 3.87Å; Y127-M215 HydrophobicContact CE2-CB 3.61Å; Y127-M215 HydrophobicContact CE2-CE 4.28Å; Y127-M215 HydrophobicContact CE2-CG 4.2Å; C211-M215 WeakPolarHBondContact O-CB 3.33Å; C211-M215 VanDerWaalsContact O-CG 3.25Å; C211-M215 WeakPolarHBondContact O-CG 3.43Å; C211-M215 PolarHBondContact O-N 3.5Å; C212-M215 PolarHBondContact O-N 2.68Å; Y213-M215 VanDerWaalsContact C-N 3.27Å; Y213-M215 PolarHBondContact O-N 3.3Å; M215-K218 PolarHBondContact O-N 3.03Å; M215-A219 WeakPolarHBondContact O-CB 3.46Å; M215-A219 PolarHBondContact O-N 2.61Å
216	I	83.4	Confident	80.3	Confident	1 Å²	1	73.6 Å²	73.6	1%	0.005	38%	0.378	C	S	.	.	H	α-helix	trans	-60.7	-48.8	173.4	-74.5	159.5	0	0	0	110.1	R126 Y127 V130 C212 Y213 K218 A219 L220	R126-I216 HydrophobicContact CB-CD1 4.18Å; Y127-I216 HydrophobicContact CD2-CG1 4.44Å; V130-I216 HydrophobicContact CB-CG1 4.5Å; V130-I216 HydrophobicContact CG1-CG2 4.49Å; C212-I216 WeakPolarHBondContact O-CD1 3.32Å; C212-I216 VanDerWaalsContact O-CG1 3.25Å; C212-I216 WeakPolarHBondContact O-CG1 3.25Å; C212-I216 PolarHBondContact O-N 3.3Å; Y213-I216 HydrophobicContact CD1-CD1 3.71Å; Y213-I216 HydrophobicContact CE1-CD1 4.2Å; Y213-I216 PolarHBondContact O-N 3.11Å; I216-K218 PolarHBondContact O-N 3.46Å; I216-A219 PolarHBondContact O-N 3.11Å; I216-L220 HydrophobicContact CG2-CD1 3.62Å; I216-L220 HydrophobicContact CG2-CG 4.24Å; I216-L220 WeakPolarHBondContact O-CB 3.41Å; I216-L220 WeakPolarHBondContact O-CG 3.34Å; I216-L220 PolarHBondContact O-N 3.29Å
217	V	81.7	Confident	78.8	Confident	59 Å²	59	75 Å²	75	36%	0.358	39%	0.388	S	S	.	.	H	α-helix	trans	-60	-47.3	178.7	170.6	0	0	0	0	110.4	Y213 G214 A219 L220 I221	Y213-V217 WeakPolarHBondContact O-CG2 3.5Å; Y213-V217 PolarHBondContact O-N 3.39Å; G214-V217 PolarHBondContact O-N 3.21Å; V217-A219 PolarHBondContact O-N 3.31Å; V217-L220 PolarHBondContact O-N 3.46Å; V217-I221 HydrophobicContact CG1-CD1 3.66Å; V217-I221 HydrophobicContact CG1-CG1 4.39Å; V217-I221 VanDerWaalsContact O-CG1 3.32Å; V217-I221 WeakPolarHBondContact O-CG1 3.27Å; V217-I221 PolarHBondContact O-N 3.3Å
218	K	84	Confident	77.2	Confident	142 Å²	142	73 Å²	73	62%	0.617	39%	0.386	S	S	*	.	H	α-helix	trans	-56.6	-47.6	175.5	-177.9	179	176.9	175.7	0	112.1	G214 M215 I216 L220 I221 Y222	G214-K218 WeakPolarHBondContact O-CB 3.32Å; G214-K218 PolarHBondContact O-N 3.37Å; M215-K218 PolarHBondContact O-N 3.03Å; I216-K218 PolarHBondContact O-N 3.46Å; K218-L220 VanDerWaalsContact C-N 3.31Å; K218-L220 PolarHBondContact O-N 2.86Å; K218-I221 PolarHBondContact O-N 3.41Å; K218-Y222 WeakPolarHBondContact O-CB 3.12Å; K218-Y222 PolarHBondContact O-N 2.91Å
219	A	79.8	Confident	75.6	Confident	12 Å²	12	73.3 Å²	73.3	10%	0.099	39%	0.393	C	S	.	.	H	α-helix	trans	-64.6	-35.4	179.5	0	0	0	0	0	112.5	V130 V131 M215 I216 V217 N223	V130-A219 HydrophobicContact CG1-CB 4.47Å; V131-A219 HydrophobicContact CG2-CB 3.87Å; M215-A219 WeakPolarHBondContact O-CB 3.46Å; M215-A219 PolarHBondContact O-N 2.61Å; I216-A219 PolarHBondContact O-N 3.11Å; V217-A219 PolarHBondContact O-N 3.31Å; A219-N223 WeakPolarHBondContact O-CB 3.19Å; A219-N223 PolarHBondContact O-N 2.9Å
220	L	76.3	Confident	74.3	Confident	16 Å²	16	77.3 Å²	77.3	8%	0.084	41%	0.414	C	S	.	.	H	α-helix	trans	-75	-26.5	177.9	-70.5	172.6	0	0	0	113.7	V130 I216 V217 K218 R231 I235	V130-L220 HydrophobicContact CG1-CD2 4.2Å; V130-L220 HydrophobicContact CG1-CG 4.4Å; I216-L220 HydrophobicContact CG2-CD1 3.62Å; I216-L220 HydrophobicContact CG2-CG 4.24Å; I216-L220 WeakPolarHBondContact O-CB 3.41Å; I216-L220 WeakPolarHBondContact O-CG 3.34Å; I216-L220 PolarHBondContact O-N 3.29Å; V217-L220 PolarHBondContact O-N 3.46Å; K218-L220 VanDerWaalsContact C-N 3.31Å; K218-L220 PolarHBondContact O-N 2.86Å; L220-R231 HydrophobicContact CB-CG 4.34Å; L220-R231 HydrophobicContact CD1-CG 4.08Å; L220-R231 HydrophobicContact CD2-CB 3.95Å; L220-R231 HydrophobicContact CD2-CG 3.83Å; L220-R231 HydrophobicContact CG-CG 4.29Å; L220-I235 HydrophobicContact CD1-CG1 4.21Å
221	I	76.9	Confident	73.2	Confident	138 Å²	138	76.4 Å²	76.4	71%	0.708	41%	0.407	S	S	*	.	H	α-helix	trans	-79.7	-42.5	174.3	-67.7	168.3	0	0	0	110.4	V217 K218	V217-I221 HydrophobicContact CG1-CD1 3.66Å; V217-I221 HydrophobicContact CG1-CG1 4.39Å; V217-I221 VanDerWaalsContact O-CG1 3.32Å; V217-I221 WeakPolarHBondContact O-CG1 3.27Å; V217-I221 PolarHBondContact O-N 3.3Å; K218-I221 PolarHBondContact O-N 3.41Å
222	Y	75.9	Confident	71.9	Confident	198 Å²	198	79 Å²	79	78%	0.776	41%	0.412	S	S	*	.	H	α-helix	trans	-82.8	-38.9	-171.7	-164	-91.9	0	0	0	113.5	K218	K218-Y222 WeakPolarHBondContact O-CB 3.12Å; K218-Y222 PolarHBondContact O-N 2.91Å
223	N	67.1	Low	70.7	Confident	81 Å²	81	80.5 Å²	80.5	43%	0.433	42%	0.417	S	S	.	.	S	Bend	trans	-91.9	117.1	173.9	-62.5	-36.4	0	0	0	107.2	A219 M225	A219-N223 WeakPolarHBondContact O-CB 3.19Å; A219-N223 PolarHBondContact O-N 2.9Å; N223-M225 HydrophobicContact CB-CG 3.87Å; N223-M225 PolarHBondContact O-N 3.01Å
224	D	57.5	Low	69.8	Low	136 Å²	136	80.3 Å²	80.3	73%	0.727	42%	0.416	S	S	*	.			trans	-67.8	66.1	168	-167	26.6	0	0	0	109.5	N226	D224-N226 PolarHBondContact O-N 3Å
225	M	57.4	Low	68.9	Low	54 Å²	54	81.3 Å²	81.3	27%	0.266	41%	0.411	S	S	.	.			trans	-69.7	101.9	178.2	-76.8	-168.1	56.5	0	0	107	N223 N227	N223-M225 HydrophobicContact CB-CG 3.87Å; N223-M225 PolarHBondContact O-N 3.01Å; M225-N227 HydrophobicContact CE-CB 4.43Å; M225-N227 PolarHBondContact O-N 3.39Å
226	N	54.8	Low	68.1	Low	148 Å²	148	81.4 Å²	81.4	79%	0.791	41%	0.41	S	S	*	.	S	Bend	trans	-51.7	1.7	169.8	-81.8	-24.9	0	0	0	115.2	D224 A228	D224-N226 PolarHBondContact O-N 3Å; N226-A228 PolarHBondContact O-N 2.75Å
227	N	59.2	Low	67.5	Low	89 Å²	89	81.5 Å²	81.5	48%	0.476	41%	0.411	S	S	.	.			trans	-90.5	63.9	173.2	-74	-49.3	0	0	0	112.1	M225 P229 L230 R231	M225-N227 HydrophobicContact CE-CB 4.43Å; M225-N227 PolarHBondContact O-N 3.39Å; N227-P229 VanDerWaalsContact C-N 3.27Å; N227-P229 VanDerWaalsContact O-N 3.13Å; N227-L230 HydrophobicContact CB-CB 4.35Å; N227-L230 HydrophobicContact CB-CD1 4.12Å; N227-L230 PolarHBondContact O-N 3Å; N227-L230 VanDerWaalsContact O-N 3.11Å; N227-R231 PolarHBondContact O-N 3.36Å
228	A	59.8	Low	67	Low	56 Å²	56	79.2 Å²	79.2	46%	0.463	40%	0.397	S	S	.	.	H	α-helix	trans	-46.5	-37.6	175.8	0	0	0	0	0	115.2	N226 L230 R231 Q232	N226-A228 PolarHBondContact O-N 2.75Å; A228-L230 PolarHBondContact O-N 2.87Å; A228-R231 PolarHBondContact O-N 3.34Å; A228-Q232 PolarHBondContact O-N 3.47Å
229	P	59.6	Low	66.4	Low	73 Å²	73	77.5 Å²	77.5	47%	0.474	39%	0.393	S	S	.	.	H	α-helix	trans	-70.8	-31.5	-179.4	-18.7	31.9	0	0	0	114.5	N227 K233	N227-P229 VanDerWaalsContact C-N 3.27Å; N227-P229 VanDerWaalsContact O-N 3.13Å; P229-K233 WeakPolarHBondContact O-CD 3.34Å; P229-K233 VanDerWaalsContact O-CG 3.29Å; P229-K233 WeakPolarHBondContact O-CG 3.49Å; P229-K233 PolarHBondContact O-N 2.87Å
230	L	61.9	Low	66.4	Low	84 Å²	84	78.2 Å²	78.2	44%	0.44	40%	0.395	S	S	.	.	H	α-helix	trans	-75.4	-36	176	-89.4	142.2	0	0	0	111	N227 A228 S234	N227-L230 HydrophobicContact CB-CB 4.35Å; N227-L230 HydrophobicContact CB-CD1 4.12Å; N227-L230 PolarHBondContact O-N 3Å; N227-L230 VanDerWaalsContact O-N 3.11Å; A228-L230 PolarHBondContact O-N 2.87Å; L230-S234 WeakPolarHBondContact O-CB 3.33Å; L230-S234 PolarHBondContact O-N 2.86Å; L230-S234 PolarHBondContact O-OG 2.96Å
231	R	64.5	Low	66.3	Low	105 Å²	105	77.5 Å²	77.5	40%	0.396	39%	0.392	S	S	.	.	H	α-helix	trans	-61.5	-53.3	174.4	-175.4	170.4	99.8	-164.4	5.6	111.4	L220 N227 A228 K233 S234 I235	L220-R231 HydrophobicContact CB-CG 4.34Å; L220-R231 HydrophobicContact CD1-CG 4.08Å; L220-R231 HydrophobicContact CD2-CB 3.95Å; L220-R231 HydrophobicContact CD2-CG 3.83Å; L220-R231 HydrophobicContact CG-CG 4.29Å; N227-R231 PolarHBondContact O-N 3.36Å; A228-R231 PolarHBondContact O-N 3.34Å; R231-K233 PolarHBondContact O-N 3.46Å; R231-S234 PolarHBondContact O-N 3.26Å; R231-I235 HydrophobicContact CG-CD1 3.94Å; R231-I235 WeakPolarHBondContact O-CG1 3.32Å; R231-I235 PolarHBondContact O-N 2.91Å; R231-I235 VanDerWaalsContact O-N 3.1Å
232	Q	64	Low	66.4	Low	126 Å²	126	73.6 Å²	73.6	59%	0.589	37%	0.372	S	S	*	.	H	α-helix	trans	-65.1	-39.1	-175.9	-163.8	172	17.7	0	0	113.1	A228 I235 H236	A228-Q232 PolarHBondContact O-N 3.47Å; Q232-I235 PolarHBondContact O-N 2.95Å; Q232-H236 PolarHBondContact O-N 3.48Å; Q232-H236 VanDerWaalsContact O-N 3.07Å; Q232-H236 PolarHBondContact O-ND1 2.03Å
233	K	64.9	Low	66.6	Low	43 Å²	43	66.4 Å²	66.4	19%	0.187	35%	0.353	C	S	.	.	H	α-helix	trans	-66.4	-39.9	175.9	-73.1	171.2	-172	158.4	0	113.3	P229 R231 I235 L237 D305	P229-K233 WeakPolarHBondContact O-CD 3.34Å; P229-K233 VanDerWaalsContact O-CG 3.29Å; P229-K233 WeakPolarHBondContact O-CG 3.49Å; P229-K233 PolarHBondContact O-N 2.87Å; R231-K233 PolarHBondContact O-N 3.46Å; K233-I235 VanDerWaalsContact C-N 3.34Å; K233-L237 VanDerWaalsContact O-CB 3.3Å; K233-L237 WeakPolarHBondContact O-CB 3.49Å; K233-L237 PolarHBondContact O-N 2.87Å; K233-D305 WeakPolarHBondContact CE-OD1 3.35Å; K233-D305 WeakPolarHBondContact CE-OD2 3.31Å; K233-D305 IonicContact NZ-OD1 3.3Å; K233-D305 IonicContact NZ-OD2 2.66Å; K233-D305 PolarHBondContact NZ-OD2 3.46Å
234	S	65	Low	67.4	Low	2 Å²	2	62.8 Å²	62.8	1%	0.014	33%	0.334	C	S	.	.	H	α-helix	trans	-66.2	-41	179	-57.9	0	0	0	0	110.3	L230 R231 L237 V238	L230-S234 WeakPolarHBondContact O-CB 3.33Å; L230-S234 PolarHBondContact O-N 2.86Å; L230-S234 PolarHBondContact O-OG 2.96Å; R231-S234 PolarHBondContact O-N 3.26Å; S234-L237 PolarHBondContact O-N 3.31Å; S234-V238 WeakPolarHBondContact O-CG2 3.49Å; S234-V238 PolarHBondContact O-N 2.88Å
235	I	67.3	Low	68.5	Low	64 Å²	64	56.3 Å²	56.3	33%	0.328	30%	0.3	S	S	.	.	H	α-helix	trans	-65.4	-45.2	177	-66.2	166.6	0	0	0	112.1	L220 R231 Q232 K233 L237 V238 I239	L220-I235 HydrophobicContact CD1-CG1 4.21Å; R231-I235 HydrophobicContact CG-CD1 3.94Å; R231-I235 WeakPolarHBondContact O-CG1 3.32Å; R231-I235 PolarHBondContact O-N 2.91Å; R231-I235 VanDerWaalsContact O-N 3.1Å; Q232-I235 PolarHBondContact O-N 2.95Å; K233-I235 VanDerWaalsContact C-N 3.34Å; I235-L237 VanDerWaalsContact C-N 3.34Å; I235-L237 PolarHBondContact O-N 2.7Å; I235-V238 WeakPolarHBondContact O-CB 3.02Å; I235-V238 PolarHBondContact O-N 3.33Å; I235-I239 HydrophobicContact CG2-CD1 3.91Å; I235-I239 WeakPolarHBondContact O-CG1 3.4Å; I235-I239 PolarHBondContact O-N 3.41Å
236	H	69.6	Low	69.8	Low	82 Å²	82	56.5 Å²	56.5	38%	0.38	31%	0.31	S	S	.	.	H	α-helix	trans	-62.8	-41.9	176.9	-78	75.1	0	0	0	112	Q232 I239 I240	Q232-H236 PolarHBondContact O-N 3.48Å; Q232-H236 VanDerWaalsContact O-N 3.07Å; Q232-H236 PolarHBondContact O-ND1 2.03Å; H236-I239 PolarHBondContact O-N 2.97Å; H236-I240 VanDerWaalsContact O-CG1 3.29Å; H236-I240 WeakPolarHBondContact O-CG1 3.46Å; H236-I240 PolarHBondContact O-N 3.29Å
237	L	69.6	Low	71.3	Confident	3 Å²	3	53.3 Å²	53.3	2%	0.016	30%	0.296	C	S	.	.	H	α-helix	trans	-60.4	-44.3	174.4	178.1	65	0	0	0	111.4	I122 R126 K233 S234 I235 I240 V241 L299	I122-L237 HydrophobicContact CG2-CD2 4.05Å; R126-L237 HydrophobicContact CG-CD2 3.8Å; K233-L237 VanDerWaalsContact O-CB 3.3Å; K233-L237 WeakPolarHBondContact O-CB 3.49Å; K233-L237 PolarHBondContact O-N 2.87Å; S234-L237 PolarHBondContact O-N 3.31Å; I235-L237 VanDerWaalsContact C-N 3.34Å; I235-L237 PolarHBondContact O-N 2.7Å; L237-I240 PolarHBondContact O-N 3.47Å; L237-V241 HydrophobicContact CD1-CG2 3.92Å; L237-V241 HydrophobicContact CG-CG2 4.45Å; L237-V241 WeakPolarHBondContact O-CB 3.32Å; L237-V241 VanDerWaalsContact O-CG2 3.24Å; L237-V241 WeakPolarHBondContact O-CG2 3.3Å; L237-V241 PolarHBondContact O-N 2.88Å; L237-L299 HydrophobicContact CD1-CD2 3.62Å
238	V	71	Confident	72.7	Confident	12 Å²	12	49.3 Å²	49.3	7%	0.073	28%	0.275	C	S	.	.	H	α-helix	trans	-56.4	-51.2	175.3	173.1	0	0	0	0	110.8	Y213 S234 I235 I240 V241 L242	Y213-V238 HydrophobicContact CD1-CB 4.11Å; Y213-V238 HydrophobicContact CD1-CG1 4.35Å; Y213-V238 HydrophobicContact CD1-CG2 3.18Å; Y213-V238 HydrophobicContact CD2-CB 4.26Å; Y213-V238 HydrophobicContact CD2-CG1 3.94Å; Y213-V238 HydrophobicContact CD2-CG2 4.19Å; Y213-V238 HydrophobicContact CE1-CB 4.38Å; Y213-V238 HydrophobicContact CE1-CG2 3.59Å; Y213-V238 HydrophobicContact CE2-CB 4.49Å; Y213-V238 HydrophobicContact CE2-CG2 4.48Å; Y213-V238 HydrophobicContact CG-CB 4.06Å; Y213-V238 HydrophobicContact CG-CG1 3.81Å; Y213-V238 HydrophobicContact CG-CG2 3.54Å; S234-V238 WeakPolarHBondContact O-CG2 3.49Å; S234-V238 PolarHBondContact O-N 2.88Å; I235-V238 WeakPolarHBondContact O-CB 3.02Å; I235-V238 PolarHBondContact O-N 3.33Å; V238-I240 PolarHBondContact O-N 3.27Å; V238-V241 PolarHBondContact O-N 3.42Å; V238-L242 HydrophobicContact CG1-CD1 3.65Å; V238-L242 HydrophobicContact CG1-CG 4.27Å; V238-L242 WeakPolarHBondContact O-CB 3.43Å; V238-L242 VanDerWaalsContact O-CG 3.27Å; V238-L242 WeakPolarHBondContact O-CG 3.34Å; V238-L242 PolarHBondContact O-N 3.22Å
239	I	73	Confident	74.2	Confident	105 Å²	105	46.7 Å²	46.7	54%	0.538	25%	0.253	S	S	.	.	H	α-helix	trans	-61.9	-48	-176.7	-68.2	167.3	0	0	0	110.7	I235 H236 A243	I235-I239 HydrophobicContact CG2-CD1 3.91Å; I235-I239 WeakPolarHBondContact O-CG1 3.4Å; I235-I239 PolarHBondContact O-N 3.41Å; H236-I239 PolarHBondContact O-N 2.97Å; I239-A243 VanDerWaalsContact O-CB 3.25Å; I239-A243 WeakPolarHBondContact O-CB 3.47Å; I239-A243 PolarHBondContact O-N 3.37Å
240	I	78.2	Confident	75.7	Confident	28 Å²	28	46.6 Å²	46.6	14%	0.144	25%	0.248	C	C	.	.	H	α-helix	trans	-65.2	-46	-178	-63.2	163.5	0	0	0	110.4	H236 L237 V238 A243 V244 V295 I298 L299 L302	H236-I240 VanDerWaalsContact O-CG1 3.29Å; H236-I240 WeakPolarHBondContact O-CG1 3.46Å; H236-I240 PolarHBondContact O-N 3.29Å; L237-I240 PolarHBondContact O-N 3.47Å; V238-I240 PolarHBondContact O-N 3.27Å; I240-A243 PolarHBondContact O-N 3.39Å; I240-V244 HydrophobicContact CG2-CG2 4.4Å; I240-V244 VanDerWaalsContact O-CG2 3.32Å; I240-V244 WeakPolarHBondContact O-CG2 3.05Å; I240-V244 PolarHBondContact O-N 2.93Å; I240-V295 HydrophobicContact CG2-CG1 3.68Å; I240-I298 HydrophobicContact CD1-CG2 4.4Å; I240-L299 HydrophobicContact CB-CD2 3.56Å; I240-L299 HydrophobicContact CD1-CD2 3.95Å; I240-L299 HydrophobicContact CG1-CD2 4.37Å; I240-L299 HydrophobicContact CG2-CD2 3.31Å; I240-L299 HydrophobicContact CG2-CG 3.88Å; I240-L302 HydrophobicContact CD1-CD1 3.84Å
241	V	75.6	Confident	77.3	Confident	1 Å²	1	44.3 Å²	44.3	1%	0.006	24%	0.238	C	C	.	.	H	α-helix	trans	-64.2	-45.8	-179.7	173.8	0	0	0	0	110.9	L119 I209 Y213 L237 V238 A243 V244 F245 L299	L119-V241 HydrophobicContact CD2-CG2 4.04Å; I209-V241 HydrophobicContact CG2-CG1 3.97Å; Y213-V241 HydrophobicContact CE2-CB 3.86Å; Y213-V241 HydrophobicContact CE2-CG1 3.8Å; L237-V241 HydrophobicContact CD1-CG2 3.92Å; L237-V241 HydrophobicContact CG-CG2 4.45Å; L237-V241 WeakPolarHBondContact O-CB 3.32Å; L237-V241 VanDerWaalsContact O-CG2 3.24Å; L237-V241 WeakPolarHBondContact O-CG2 3.3Å; L237-V241 PolarHBondContact O-N 2.88Å; V238-V241 PolarHBondContact O-N 3.42Å; V241-A243 VanDerWaalsContact C-N 3.32Å; V241-A243 PolarHBondContact O-N 3.41Å; V241-V244 PolarHBondContact O-N 2.99Å; V241-F245 HydrophobicContact CG1-CD2 3.91Å; V241-F245 HydrophobicContact CG1-CE2 3.98Å; V241-F245 WeakPolarHBondContact O-CD2 3.49Å; V241-F245 PolarHBondContact O-N 2.92Å; V241-L299 HydrophobicContact CG2-CD1 4.22Å; V241-L299 HydrophobicContact CG2-CD2 4.26Å
242	L	78.6	Confident	78.7	Confident	55 Å²	55	39.3 Å²	39.3	29%	0.288	22%	0.219	S	C	.	.	H	α-helix	trans	-61.8	-40.2	176.5	-70.9	177.2	0	0	0	112.1	F210 Y213 V238 F245 A246	F210-L242 HydrophobicContact CD2-CD2 4.45Å; Y213-L242 HydrophobicContact CD2-CD2 4.38Å; Y213-L242 HydrophobicContact CD2-CG 4.28Å; V238-L242 HydrophobicContact CG1-CD1 3.65Å; V238-L242 HydrophobicContact CG1-CG 4.27Å; V238-L242 WeakPolarHBondContact O-CB 3.43Å; V238-L242 VanDerWaalsContact O-CG 3.27Å; V238-L242 WeakPolarHBondContact O-CG 3.34Å; V238-L242 PolarHBondContact O-N 3.22Å; L242-F245 PolarHBondContact O-N 2.84Å; L242-A246 WeakPolarHBondContact O-CB 3.35Å; L242-A246 PolarHBondContact O-N 3.23Å
243	A	80.8	Confident	80.2	Confident	47 Å²	47	33.4 Å²	33.4	39%	0.388	19%	0.191	S	C	.	.	H	α-helix	trans	-62.9	-43.8	175.7	0	0	0	0	0	111.9	I239 I240 V241 F245 A246 V247	I239-A243 VanDerWaalsContact O-CB 3.25Å; I239-A243 WeakPolarHBondContact O-CB 3.47Å; I239-A243 PolarHBondContact O-N 3.37Å; I240-A243 PolarHBondContact O-N 3.39Å; V241-A243 VanDerWaalsContact C-N 3.32Å; V241-A243 PolarHBondContact O-N 3.41Å; A243-F245 VanDerWaalsContact C-N 3.35Å; A243-F245 PolarHBondContact O-N 2.93Å; A243-A246 PolarHBondContact O-N 3.47Å; A243-V247 WeakPolarHBondContact O-CB 3.12Å; A243-V247 WeakPolarHBondContact O-CG2 3.22Å; A243-V247 PolarHBondContact O-N 2.91Å
244	V	82.4	Confident	81.7	Confident	6 Å²	6	35.1 Å²	35.1	4%	0.036	21%	0.205	C	C	.	.	H	α-helix	trans	-58.8	-46.3	175.3	166.4	0	0	0	0	111	I240 V241 S248 Y249 N292 V295	I240-V244 HydrophobicContact CG2-CG2 4.4Å; I240-V244 VanDerWaalsContact O-CG2 3.32Å; I240-V244 WeakPolarHBondContact O-CG2 3.05Å; I240-V244 PolarHBondContact O-N 2.93Å; V241-V244 PolarHBondContact O-N 2.99Å; V244-S248 WeakPolarHBondContact O-CA 3.31Å; V244-S248 WeakPolarHBondContact O-CB 3.42Å; V244-S248 PolarHBondContact O-N 2.78Å; V244-S248 PolarHBondContact O-OG 3.05Å; V244-Y249 HydrophobicContact CG1-CD2 3.99Å; V244-Y249 HydrophobicContact CG1-CE2 3.55Å; V244-Y249 PolarHBondContact O-N 2.75Å; V244-N292 WeakPolarHBondContact CG1-OD1 3.47Å; V244-V295 HydrophobicContact CG2-CB 4.11Å; V244-V295 HydrophobicContact CG2-CG1 3.58Å
245	F	82	Confident	83.1	Confident	0 Å²	0	36.1 Å²	36.1	0%	0	21%	0.21	C	C	.	.	I	π-helix	trans	-63.6	-43.5	177.1	-89.4	-94.6	0	0	0	112.4	I116 L119 F202 F206 I209 V241 L242 A243 Y249 L250	I116-F245 HydrophobicContact CB-CZ 4.42Å; I116-F245 HydrophobicContact CG1-CE1 4.33Å; I116-F245 HydrophobicContact CG1-CZ 4.17Å; I116-F245 HydrophobicContact CG2-CE1 4.27Å; I116-F245 HydrophobicContact CG2-CZ 4.04Å; L119-F245 HydrophobicContact CB-CE2 4.45Å; L119-F245 HydrophobicContact CD1-CE2 4Å; F202-F245 HydrophobicContact CD2-CD1 4.35Å; F202-F245 HydrophobicContact CD2-CE1 4.17Å; F202-F245 AromaticContact CE2-CD1 3.69Å; F202-F245 HydrophobicContact CE2-CD1 3.69Å; F202-F245 AromaticContact CE2-CE1 3.97Å; F202-F245 HydrophobicContact CE2-CE1 3.97Å; F206-F245 HydrophobicContact CB-CD1 4.24Å; F206-F245 HydrophobicContact CB-CE1 4.18Å; F206-F245 HydrophobicContact CD2-CB 4Å; F206-F245 AromaticContact CD2-CD1 3.42Å; F206-F245 HydrophobicContact CD2-CD1 3.42Å; F206-F245 VanDerWaalsContact CD2-CD1 3.42Å; F206-F245 HydrophobicContact CD2-CE1 4.13Å; F206-F245 AromaticContact CD2-CG 3.89Å; F206-F245 HydrophobicContact CD2-CG 3.89Å; F206-F245 HydrophobicContact CE2-CB 3.93Å; F206-F245 HydrophobicContact CE2-CD1 4.21Å; F206-F245 HydrophobicContact CE2-CG 4.32Å; F206-F245 HydrophobicContact CG-CD1 4.25Å; I209-F245 HydrophobicContact CD1-CD2 4.4Å; I209-F245 HydrophobicContact CD1-CE1 4.27Å; I209-F245 HydrophobicContact CD1-CE2 3.44Å; I209-F245 VanDerWaalsContact CD1-CE2 3.44Å; I209-F245 HydrophobicContact CD1-CZ 3.35Å; V241-F245 HydrophobicContact CG1-CD2 3.91Å; V241-F245 HydrophobicContact CG1-CE2 3.98Å; V241-F245 WeakPolarHBondContact O-CD2 3.49Å; V241-F245 PolarHBondContact O-N 2.92Å; L242-F245 PolarHBondContact O-N 2.84Å; A243-F245 VanDerWaalsContact C-N 3.35Å; A243-F245 PolarHBondContact O-N 2.93Å; F245-Y249 HydrophobicContact CB-CD2 4.49Å; F245-Y249 AromaticContact CD1-CD2 3.78Å; F245-Y249 HydrophobicContact CD1-CD2 3.78Å; F245-Y249 AromaticContact CD2-CD2 3.86Å; F245-Y249 HydrophobicContact CD2-CD2 3.86Å; F245-Y249 HydrophobicContact CD2-CE2 4.19Å; F245-Y249 AromaticContact CE1-CD2 3.86Å; F245-Y249 HydrophobicContact CE1-CD2 3.86Å; F245-Y249 AromaticContact CE2-CD2 3.93Å; F245-Y249 HydrophobicContact CE2-CD2 3.93Å; F245-Y249 AromaticContact CE2-CE2 3.97Å; F245-Y249 HydrophobicContact CE2-CE2 3.97Å; F245-Y249 AromaticContact CG-CD2 3.8Å; F245-Y249 HydrophobicContact CG-CD2 3.8Å; F245-Y249 AromaticContact CZ-CD2 3.93Å; F245-Y249 HydrophobicContact CZ-CD2 3.93Å; F245-Y249 HydrophobicContact CZ-CE2 4.15Å; F245-Y249 PolarHBondContact O-N 3.25Å; F245-L250 VanDerWaalsContact O-CB 3.24Å; F245-L250 WeakPolarHBondContact O-CB 3.25Å; F245-L250 PolarHBondContact O-N 3.49Å
246	A	83	Confident	84.4	Confident	58 Å²	58	33.1 Å²	33.1	48%	0.479	19%	0.194	S	C	.	.	I	π-helix	trans	-70.4	-38.1	-178	0	0	0	0	0	113.3	L242 A243 P251	L242-A246 WeakPolarHBondContact O-CB 3.35Å; L242-A246 PolarHBondContact O-N 3.23Å; A243-A246 PolarHBondContact O-N 3.47Å; A246-P251 VanDerWaalsContact O-CD 3.22Å; A246-P251 WeakPolarHBondContact O-CD 3.13Å; A246-P251 VanDerWaalsContact O-CG 3.23Å; A246-P251 WeakPolarHBondContact O-CG 3.41Å
247	V	86.3	Confident	85.6	Confident	81 Å²	81	29.7 Å²	29.7	49%	0.491	18%	0.179	S	C	.	.	I	π-helix	trans	-93.4	-32.6	-173.8	178.1	0	0	0	0	112.3	A243 P251 L288	A243-V247 WeakPolarHBondContact O-CB 3.12Å; A243-V247 WeakPolarHBondContact O-CG2 3.22Å; A243-V247 PolarHBondContact O-N 2.91Å; V247-P251 WeakPolarHBondContact O-CG 3.37Å; V247-L288 WeakPolarHBondContact O-CD1 3.06Å
248	S	88.8	Confident	86.8	Confident	5 Å²	5	32 Å²	32	4%	0.035	19%	0.191	C	C	.	.	I	π-helix	trans	-108.5	-60.7	-171.4	-48.3	0	0	0	0	111.8	V244 F252 L288	V244-S248 WeakPolarHBondContact O-CA 3.31Å; V244-S248 WeakPolarHBondContact O-CB 3.42Å; V244-S248 PolarHBondContact O-N 2.78Å; V244-S248 PolarHBondContact O-OG 3.05Å; S248-F252 VanDerWaalsContact O-CB 3.29Å; S248-F252 WeakPolarHBondContact O-CB 3.49Å; S248-F252 PolarHBondContact O-N 2.89Å; S248-L288 WeakPolarHBondContact CB-O 3.48Å; S248-L288 PolarHBondContact OG-O 3.48Å
249	Y	91.2	Very high	87.8	Confident	1 Å²	1	31.9 Å²	31.9	0%	0.004	19%	0.19	C	C	.	.	I	π-helix	trans	-77.4	-46.2	-169.2	-60.8	-41.1	0	0	0	114.1	L112 S115 I116 L119 V244 F245 F252 H253 N292	L112-Y249 HydrophobicContact CD1-CD1 3.44Å; L112-Y249 VanDerWaalsContact CD1-CD1 3.44Å; L112-Y249 HydrophobicContact CD1-CE1 3.46Å; L112-Y249 VanDerWaalsContact CD1-CE1 3.46Å; S115-Y249 WeakPolarHBondContact CB-OH 3.3Å; I116-Y249 HydrophobicContact CD1-CD1 4.4Å; I116-Y249 HydrophobicContact CD1-CG 4.34Å; I116-Y249 HydrophobicContact CG1-CD1 4.44Å; I116-Y249 HydrophobicContact CG1-CD2 3.97Å; I116-Y249 HydrophobicContact CG1-CE1 4.3Å; I116-Y249 HydrophobicContact CG1-CE2 3.84Å; I116-Y249 HydrophobicContact CG1-CG 4.26Å; L119-Y249 HydrophobicContact CD1-CE2 4.04Å; V244-Y249 HydrophobicContact CG1-CD2 3.99Å; V244-Y249 HydrophobicContact CG1-CE2 3.55Å; V244-Y249 PolarHBondContact O-N 2.75Å; F245-Y249 HydrophobicContact CB-CD2 4.49Å; F245-Y249 AromaticContact CD1-CD2 3.78Å; F245-Y249 HydrophobicContact CD1-CD2 3.78Å; F245-Y249 AromaticContact CD2-CD2 3.86Å; F245-Y249 HydrophobicContact CD2-CD2 3.86Å; F245-Y249 HydrophobicContact CD2-CE2 4.19Å; F245-Y249 AromaticContact CE1-CD2 3.86Å; F245-Y249 HydrophobicContact CE1-CD2 3.86Å; F245-Y249 AromaticContact CE2-CD2 3.93Å; F245-Y249 HydrophobicContact CE2-CD2 3.93Å; F245-Y249 AromaticContact CE2-CE2 3.97Å; F245-Y249 HydrophobicContact CE2-CE2 3.97Å; F245-Y249 AromaticContact CG-CD2 3.8Å; F245-Y249 HydrophobicContact CG-CD2 3.8Å; F245-Y249 AromaticContact CZ-CD2 3.93Å; F245-Y249 HydrophobicContact CZ-CD2 3.93Å; F245-Y249 HydrophobicContact CZ-CE2 4.15Å; F245-Y249 PolarHBondContact O-N 3.25Å; Y249-F252 PolarHBondContact O-N 3.14Å; Y249-H253 PolarHBondContact O-N 2.7Å; Y249-H253 PolarHBondContact O-ND1 2.97Å; Y249-N292 HydrophobicContact CE1-CB 4.07Å; Y249-N292 PolarHBondContact OH-ND2 2.96Å; Y249-N292 PolarHBondContact OH-OD1 3.01Å
250	L	92.1	Very high	88.7	Confident	71 Å²	71	26.9 Å²	26.9	37%	0.372	16%	0.164	S	C	.	.	H	α-helix	trans	-62.8	-50.2	-178.8	177.7	65.4	0	0	0	111.6	F202 F245 F252 H253 V254	F202-L250 HydrophobicContact CE1-CD1 3.83Å; F202-L250 HydrophobicContact CZ-CB 3.84Å; F202-L250 HydrophobicContact CZ-CD1 3.8Å; F202-L250 HydrophobicContact CZ-CG 4.45Å; F245-L250 VanDerWaalsContact O-CB 3.24Å; F245-L250 WeakPolarHBondContact O-CB 3.25Å; F245-L250 PolarHBondContact O-N 3.49Å; L250-F252 VanDerWaalsContact C-N 3.27Å; L250-F252 PolarHBondContact O-N 2.81Å; L250-H253 PolarHBondContact O-N 2.92Å; L250-V254 HydrophobicContact CD1-CG2 4.01Å; L250-V254 HydrophobicContact CG-CG2 4.45Å; L250-V254 WeakPolarHBondContact O-CG2 3.43Å; L250-V254 PolarHBondContact O-N 3.43Å
251	P	94.6	Very high	89.4	Confident	35 Å²	35	31.9 Å²	31.9	23%	0.227	18%	0.181	C	C	.	.	H	α-helix	trans	-62.4	-36.7	179	-24.1	37.8	0	0	0	112	A246 V247 M255 T285	A246-P251 VanDerWaalsContact O-CD 3.22Å; A246-P251 WeakPolarHBondContact O-CD 3.13Å; A246-P251 VanDerWaalsContact O-CG 3.23Å; A246-P251 WeakPolarHBondContact O-CG 3.41Å; V247-P251 WeakPolarHBondContact O-CG 3.37Å; P251-M255 VanDerWaalsContact O-CB 3.26Å; P251-M255 WeakPolarHBondContact O-CB 3.19Å; P251-M255 WeakPolarHBondContact O-CG 3.48Å; P251-M255 PolarHBondContact O-N 3.11Å; P251-T285 HydrophobicContact CB-CG2 3.51Å
252	F	95.3	Very high	90.2	Very high	0 Å²	0	32 Å²	32	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-62.2	-49.8	175.9	173.2	-100.4	0	0	0	112.3	F108 L112 S248 Y249 L250 M255 K256 Y282 R286 A289	F108-F252 HydrophobicContact CE1-CE1 4.49Å; F108-F252 HydrophobicContact CE1-CE2 4.18Å; F108-F252 AromaticContact CE1-CZ 3.75Å; F108-F252 HydrophobicContact CE1-CZ 3.75Å; F108-F252 HydrophobicContact CZ-CE2 4.02Å; F108-F252 AromaticContact CZ-CZ 3.92Å; F108-F252 HydrophobicContact CZ-CZ 3.92Å; L112-F252 HydrophobicContact CD2-CD1 3.87Å; L112-F252 HydrophobicContact CD2-CE1 3.37Å; L112-F252 HydrophobicContact CD2-CZ 4.22Å; S248-F252 VanDerWaalsContact O-CB 3.29Å; S248-F252 WeakPolarHBondContact O-CB 3.49Å; S248-F252 PolarHBondContact O-N 2.89Å; Y249-F252 PolarHBondContact O-N 3.14Å; L250-F252 VanDerWaalsContact C-N 3.27Å; L250-F252 PolarHBondContact O-N 2.81Å; F252-M255 PolarHBondContact O-N 3.31Å; F252-K256 HydrophobicContact CE1-CD 4.03Å; F252-K256 HydrophobicContact CZ-CB 4.49Å; F252-K256 HydrophobicContact CZ-CD 3.86Å; F252-K256 WeakPolarHBondContact O-CB 3.4Å; F252-K256 PolarHBondContact O-N 2.85Å; F252-Y282 HydrophobicContact CD2-CE2 4.34Å; F252-Y282 AromaticContact CE2-CE2 3.96Å; F252-Y282 HydrophobicContact CE2-CE2 3.96Å; F252-R286 HydrophobicContact CD2-CG 4.07Å; F252-R286 HydrophobicContact CE2-CG 3.84Å; F252-A289 HydrophobicContact CB-CB 3.99Å; F252-A289 HydrophobicContact CD2-CB 3.98Å; F252-A289 HydrophobicContact CG-CB 3.91Å
253	H	95.3	Very high	90.7	Very high	3 Å²	3	31.7 Å²	31.7	1%	0.014	18%	0.178	C	C	.	.	H	α-helix	trans	-65	-42.3	-179.1	-76.2	81.9	0	0	0	112.1	Y113 T198 F202 Y249 L250 N257	Y113-H253 AromaticContact CE1-NE2 3.71Å; Y113-H253 AromaticContact CZ-NE2 3.74Å; Y113-H253 PolarHBondContact OH-NE2 2.72Å; T198-H253 HydrophobicContact CG2-CB 4.16Å; F202-H253 WeakPolarHBondContact CB-NE2 3.18Å; F202-H253 HydrophobicContact CD1-CB 4.15Å; F202-H253 AromaticContact CD1-CG 3.92Å; F202-H253 AromaticContact CD2-CE1 3.73Å; F202-H253 AromaticContact CD2-ND1 3.68Å; F202-H253 HydrophobicContact CE1-CB 4.36Å; F202-H253 AromaticContact CG-CD2 3.89Å; F202-H253 AromaticContact CG-CE1 3.77Å; F202-H253 AromaticContact CG-CG 3.8Å; F202-H253 AromaticContact CG-ND1 3.72Å; F202-H253 AromaticContact CG-NE2 3.89Å; Y249-H253 PolarHBondContact O-N 2.7Å; Y249-H253 PolarHBondContact O-ND1 2.97Å; L250-H253 PolarHBondContact O-N 2.92Å; H253-N257 WeakPolarHBondContact O-CB 3.36Å; H253-N257 PolarHBondContact O-N 2.95Å; H253-N257 PolarHBondContact O-ND2 3.37Å
254	V	95.4	Very high	91.1	Very high	79 Å²	79	31.5 Å²	31.5	48%	0.479	17%	0.169	S	C	.	.	H	α-helix	trans	-60.4	-52.1	176.2	171.7	0	0	0	0	110.1	L250 N257 L258	L250-V254 HydrophobicContact CD1-CG2 4.01Å; L250-V254 HydrophobicContact CG-CG2 4.45Å; L250-V254 WeakPolarHBondContact O-CG2 3.43Å; L250-V254 PolarHBondContact O-N 3.43Å; V254-N257 PolarHBondContact O-N 2.97Å; V254-L258 VanDerWaalsContact O-CB 3.28Å; V254-L258 WeakPolarHBondContact O-CB 3.48Å; V254-L258 PolarHBondContact O-N 3.13Å
255	M	96	Very high	91.4	Very high	22 Å²	22	38.3 Å²	38.3	11%	0.108	20%	0.196	C	C	.	.	H	α-helix	trans	-72.8	-33.8	-174.8	-65.6	-53.3	-49.6	0	0	113.5	P251 F252 L258 N259 V278 T281 Y282 T285	P251-M255 VanDerWaalsContact O-CB 3.26Å; P251-M255 WeakPolarHBondContact O-CB 3.19Å; P251-M255 WeakPolarHBondContact O-CG 3.48Å; P251-M255 PolarHBondContact O-N 3.11Å; F252-M255 PolarHBondContact O-N 3.31Å; M255-L258 HydrophobicContact CE-CD2 4.15Å; M255-L258 HydrophobicContact SD-CD2 4.28Å; M255-N259 WeakPolarHBondContact O-CB 3.38Å; M255-N259 PolarHBondContact O-N 2.96Å; M255-V278 HydrophobicContact CE-CB 4.35Å; M255-V278 HydrophobicContact CE-CG1 3.97Å; M255-V278 VanDerWaalsContact CE-O 3.31Å; M255-V278 WeakPolarHBondContact CE-O 3.23Å; M255-T281 HydrophobicContact CE-CG2 3.76Å; M255-T281 HydrophobicContact CG-CG2 3.99Å; M255-T281 HydrophobicContact SD-CG2 3.8Å; M255-Y282 HydrophobicContact CB-CD2 4.2Å; M255-T285 HydrophobicContact CB-CG2 4.23Å; M255-T285 WeakPolarHBondContact CB-OG1 3.34Å; M255-T285 HydrophobicContact CG-CG2 3.7Å
256	K	94.3	Very high	91.8	Very high	1 Å²	1	40.9 Å²	40.9	0%	0.004	21%	0.207	C	C	.	.	H	α-helix	trans	-57.6	-53.2	173.9	178.2	-179.1	175.3	177.5	0	110.3	H109 Y190 S194 F252 N259 M260 Y282	H109-K256 PolarHBondContact NE2-NZ 3.34Å; Y190-K256 PolarHBondContact OH-NZ 3.41Å; S194-K256 WeakPolarHBondContact OG-CE 3.36Å; F252-K256 HydrophobicContact CE1-CD 4.03Å; F252-K256 HydrophobicContact CZ-CB 4.49Å; F252-K256 HydrophobicContact CZ-CD 3.86Å; F252-K256 WeakPolarHBondContact O-CB 3.4Å; F252-K256 PolarHBondContact O-N 2.85Å; K256-N259 PolarHBondContact O-N 3.48Å; K256-M260 HydrophobicContact CG-SD 4.29Å; K256-M260 WeakPolarHBondContact O-CG 3.44Å; K256-M260 PolarHBondContact O-N 3.09Å; K256-Y282 HydrophobicContact CB-CD2 4.32Å; K256-Y282 HydrophobicContact CB-CE2 3.72Å; K256-Y282 HydrophobicContact CG-CE2 4.2Å
257	N	94.1	Very high	92.1	Very high	11 Å²	11	41.1 Å²	41.1	6%	0.059	20%	0.198	C	C	.	.	H	α-helix	trans	-69.9	-37.3	-177.6	-74.4	-62.2	0	0	0	112.2	S194 M195 T198 H253 V254 M260 R261	S194-N257 PolarHBondContact OG-OD1 3.09Å; S194-N257 VanDerWaalsContact OG-OD1 3.04Å; M195-N257 HydrophobicContact CE-CB 3.47Å; M195-N257 VanDerWaalsContact CE-CB 3.47Å; M195-N257 WeakPolarHBondContact CE-OD1 3.39Å; M195-N257 HydrophobicContact SD-CB 4.47Å; T198-N257 PolarHBondContact OG1-ND2 2.64Å; H253-N257 WeakPolarHBondContact O-CB 3.36Å; H253-N257 PolarHBondContact O-N 2.95Å; H253-N257 PolarHBondContact O-ND2 3.37Å; V254-N257 PolarHBondContact O-N 2.97Å; N257-M260 PolarHBondContact O-N 2.7Å; N257-R261 WeakPolarHBondContact O-CB 3.26Å; N257-R261 PolarHBondContact O-N 2.99Å
258	L	94.8	Very high	92.2	Very high	51 Å²	51	39.8 Å²	39.8	27%	0.267	19%	0.192	S	C	.	.	H	α-helix	trans	-64.2	-42.7	174.3	-176.6	59	0	0	0	111.7	V254 M255 M260 R261 A262 F274 V278	V254-L258 VanDerWaalsContact O-CB 3.28Å; V254-L258 WeakPolarHBondContact O-CB 3.48Å; V254-L258 PolarHBondContact O-N 3.13Å; M255-L258 HydrophobicContact CE-CD2 4.15Å; M255-L258 HydrophobicContact SD-CD2 4.28Å; L258-M260 VanDerWaalsContact C-N 3.32Å; L258-M260 PolarHBondContact O-N 3.42Å; L258-R261 PolarHBondContact O-N 2.97Å; L258-A262 VanDerWaalsContact O-CB 3.3Å; L258-A262 WeakPolarHBondContact O-CB 3.43Å; L258-A262 PolarHBondContact O-N 3.28Å; L258-F274 HydrophobicContact CD1-CZ 4.3Å; L258-F274 HydrophobicContact CD2-CZ 4.39Å; L258-V278 HydrophobicContact CB-CG1 4.38Å; L258-V278 HydrophobicContact CD2-CG1 4.28Å; L258-V278 HydrophobicContact CD2-CG2 3.86Å; L258-V278 HydrophobicContact CG-CG1 3.89Å; L258-V278 HydrophobicContact CG-CG2 4.05Å
259	N	92.9	Very high	92.1	Very high	9 Å²	9	44.1 Å²	44.1	5%	0.048	22%	0.221	C	C	.	.	H	α-helix	trans	-63	-37.5	175.8	178.4	76.5	0	0	0	112.1	M255 K256 R263 V278 Y282	M255-N259 WeakPolarHBondContact O-CB 3.38Å; M255-N259 PolarHBondContact O-N 2.96Å; K256-N259 PolarHBondContact O-N 3.48Å; N259-R263 WeakPolarHBondContact O-CG 3.42Å; N259-R263 PolarHBondContact O-N 3.47Å; N259-R263 VanDerWaalsContact O-N 3.12Å; N259-V278 VanDerWaalsContact CA-CG1 3.49Å; N259-V278 HydrophobicContact CB-CG1 3.86Å; N259-Y282 HydrophobicContact CB-CD1 4.24Å; N259-Y282 HydrophobicContact CB-CG 4.13Å
260	M	91.6	Very high	92	Very high	0 Å²	0	51.2 Å²	51.2	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-69.4	-42.5	174	-69.5	175.8	60	0	0	112.3	T181 L187 Y190 F191 K256 N257 L258 A262 R263 L264	T181-M260 HydrophobicContact CG2-CG 4.34Å; T181-M260 HydrophobicContact CG2-SD 4.19Å; L187-M260 HydrophobicContact CD1-CE 4.17Å; L187-M260 HydrophobicContact CD1-CG 4.49Å; Y190-M260 HydrophobicContact CD1-CE 3.23Å; Y190-M260 HydrophobicContact CD1-SD 3.89Å; Y190-M260 HydrophobicContact CE1-CE 3.74Å; Y190-M260 HydrophobicContact CE1-SD 3.73Å; Y190-M260 HydrophobicContact CG-CE 4.24Å; F191-M260 HydrophobicContact CB-CE 3.68Å; F191-M260 HydrophobicContact CD2-CB 3.88Å; F191-M260 HydrophobicContact CD2-CE 4.06Å; F191-M260 HydrophobicContact CG-CE 4.38Å; K256-M260 HydrophobicContact CG-SD 4.29Å; K256-M260 WeakPolarHBondContact O-CG 3.44Å; K256-M260 PolarHBondContact O-N 3.09Å; N257-M260 PolarHBondContact O-N 2.7Å; L258-M260 VanDerWaalsContact C-N 3.32Å; L258-M260 PolarHBondContact O-N 3.42Å; M260-A262 VanDerWaalsContact C-N 3.3Å; M260-A262 PolarHBondContact O-N 3.13Å; M260-R263 PolarHBondContact O-N 2.86Å; M260-L264 WeakPolarHBondContact O-CG 3.32Å; M260-L264 PolarHBondContact O-N 2.93Å
261	R	92.7	Very high	91.9	Very high	133 Å²	133	50.5 Å²	50.5	50%	0.502	25%	0.254	S	S	.	.	H	α-helix	trans	-61.4	-40.7	175.2	-166.4	178.2	-175.7	169.4	0.5	111.6	F191 N257 L258 L264 Y265 F266	F191-R261 HydrophobicContact CE2-CB 4.28Å; N257-R261 WeakPolarHBondContact O-CB 3.26Å; N257-R261 PolarHBondContact O-N 2.99Å; L258-R261 PolarHBondContact O-N 2.97Å; R261-L264 PolarHBondContact O-N 3.39Å; R261-Y265 HydrophobicContact CG-CD2 3.76Å; R261-Y265 HydrophobicContact CG-CE2 4.42Å; R261-Y265 PolarHBondContact O-N 3.06Å; R261-F266 HydrophobicContact CG-CE2 4.29Å; R261-F266 HydrophobicContact CG-CZ 4.31Å
262	A	91.6	Very high	91.7	Very high	3 Å²	3	50.2 Å²	50.2	3%	0.025	25%	0.252	C	S	.	.	H	α-helix	trans	-59.7	-46	174.9	0	0	0	0	0	112.2	L258 M260 L264 F266 Q267 N275 V278	L258-A262 VanDerWaalsContact O-CB 3.3Å; L258-A262 WeakPolarHBondContact O-CB 3.43Å; L258-A262 PolarHBondContact O-N 3.28Å; M260-A262 VanDerWaalsContact C-N 3.3Å; M260-A262 PolarHBondContact O-N 3.13Å; A262-L264 VanDerWaalsContact C-N 3.34Å; A262-L264 PolarHBondContact O-N 3.12Å; A262-F266 HydrophobicContact CB-CD2 4.15Å; A262-F266 CarbonylContact O-C 3.59Å; A262-F266 PolarHBondContact O-N 3.27Å; A262-F266 VanDerWaalsContact O-N 3.08Å; A262-Q267 PolarHBondContact O-NE2 3.14Å; A262-N275 WeakPolarHBondContact CB-OD1 3.32Å; A262-V278 HydrophobicContact CB-CG1 4.41Å
263	R	89.6	Confident	91.4	Very high	50 Å²	50	55.8 Å²	55.8	19%	0.189	28%	0.279	C	S	.	.	H	α-helix	trans	-62.7	-36.6	175.5	-74.5	172.6	63.4	-167.5	0.7	113.4	T181 T182 E184 L187 N259 M260 Q267	T181-R263 PolarHBondContact OG1-NH1 3.01Å; T182-R263 PolarHBondContact O-NH2 3.28Å; T182-R263 VanDerWaalsContact O-NH2 3.16Å; E184-R263 IonicContact OE1-CZ 2.91Å; E184-R263 IonicContact OE1-NE 2.74Å; E184-R263 PolarHBondContact OE1-NE 3.5Å; E184-R263 IonicContact OE1-NH2 3.46Å; E184-R263 PolarHBondContact OE1-NH2 2.94Å; E184-R263 IonicContact OE2-NE 3.75Å; E184-R263 IonicContact OE2-NH2 3.94Å; L187-R263 HydrophobicContact CD2-CB 3.58Å; N259-R263 WeakPolarHBondContact O-CG 3.42Å; N259-R263 PolarHBondContact O-N 3.47Å; N259-R263 VanDerWaalsContact O-N 3.12Å; M260-R263 PolarHBondContact O-N 2.86Å; R263-Q267 WeakPolarHBondContact O-CG 3.49Å; R263-Q267 PolarHBondContact O-NE2 3.16Å
264	L	89.6	Confident	91.3	Very high	42 Å²	42	59.5 Å²	59.5	22%	0.22	30%	0.295	C	S	.	.	H	α-helix	trans	-80.6	-43.7	-178.5	-74.7	170.4	0	0	0	113.9	L187 P188 F191 M260 R261 A262	L187-L264 HydrophobicContact CB-CD2 3.97Å; L187-L264 HydrophobicContact CD2-CD2 3.76Å; L187-L264 HydrophobicContact CD2-CG 3.76Å; L187-L264 HydrophobicContact CG-CD1 4.33Å; L187-L264 HydrophobicContact CG-CD2 3.78Å; L187-L264 HydrophobicContact CG-CG 3.89Å; P188-L264 HydrophobicContact CG-CD2 3.84Å; F191-L264 HydrophobicContact CB-CD1 3.7Å; F191-L264 HydrophobicContact CD1-CD1 4.26Å; F191-L264 HydrophobicContact CD2-CD1 4.23Å; F191-L264 HydrophobicContact CG-CD1 3.82Å; M260-L264 WeakPolarHBondContact O-CG 3.32Å; M260-L264 PolarHBondContact O-N 2.93Å; R261-L264 PolarHBondContact O-N 3.39Å; A262-L264 VanDerWaalsContact C-N 3.34Å; A262-L264 PolarHBondContact O-N 3.12Å
265	Y	89.4	Confident	91.1	Very high	149 Å²	149	56 Å²	56	58%	0.584	27%	0.273	S	S	*	.	H	α-helix	trans	-122	-19.8	-163.6	-57.8	-70.3	0	0	0	114.5	R261	R261-Y265 HydrophobicContact CG-CD2 3.76Å; R261-Y265 HydrophobicContact CG-CE2 4.42Å; R261-Y265 PolarHBondContact O-N 3.06Å
266	F	90.1	Very high	90.8	Very high	54 Å²	54	56.7 Å²	56.7	24%	0.237	28%	0.278	C	S	.	.			trans	-107.9	44	-173.9	-53.6	-31.4	0	0	0	112	R261 A262 S268 M271 F274 N275	R261-F266 HydrophobicContact CG-CE2 4.29Å; R261-F266 HydrophobicContact CG-CZ 4.31Å; A262-F266 HydrophobicContact CB-CD2 4.15Å; A262-F266 CarbonylContact O-C 3.59Å; A262-F266 PolarHBondContact O-N 3.27Å; A262-F266 VanDerWaalsContact O-N 3.08Å; F266-S268 VanDerWaalsContact C-N 3.32Å; F266-M271 HydrophobicContact CB-CB 4.06Å; F266-M271 HydrophobicContact CB-CE 4.03Å; F266-M271 HydrophobicContact CB-CG 4.28Å; F266-M271 HydrophobicContact CD1-CE 4.36Å; F266-M271 HydrophobicContact CD2-CE 4.09Å; F266-M271 HydrophobicContact CG-CE 3.93Å; F266-M271 WeakPolarHBondContact O-CB 3.49Å; F266-F274 HydrophobicContact CD2-CD1 4.45Å; F266-F274 AromaticContact CD2-CE1 3.94Å; F266-F274 HydrophobicContact CD2-CE1 3.94Å; F266-F274 HydrophobicContact CE2-CE1 4.26Å; F266-N275 PolarHBondContact O-ND2 3.32Å
267	Q	88.4	Confident	90.7	Very high	63 Å²	63	64.3 Å²	64.3	29%	0.294	31%	0.306	S	S	.	.			trans	-88.2	7.9	-178.4	-65.7	-56.8	-59.2	0	0	114.2	R17 A262 R263 N275	R17-Q267 VanDerWaalsContact O-O 3.07Å; A262-Q267 PolarHBondContact O-NE2 3.14Å; R263-Q267 WeakPolarHBondContact O-CG 3.49Å; R263-Q267 PolarHBondContact O-NE2 3.16Å; Q267-N275 PolarHBondContact NE2-ND2 3.44Å
268	S	87.9	Confident	90.7	Very high	53 Å²	53	64.1 Å²	64.1	37%	0.371	31%	0.306	S	S	.	.	S	Bend	trans	-67.9	149.8	174.3	56.2	0	0	0	0	111.8	F266 D270 M271	F266-S268 VanDerWaalsContact C-N 3.32Å; S268-D270 VanDerWaalsContact C-N 3.25Å; S268-D270 PolarHBondContact O-N 3.47Å; S268-M271 PolarHBondContact O-N 3.08Å; S268-M271 VanDerWaalsContact OG-CG 3.23Å; S268-M271 WeakPolarHBondContact OG-CG 3.47Å
269	P	86.8	Confident	90.5	Very high	97 Å²	97	63.5 Å²	63.5	63%	0.63	30%	0.3	S	S	*	.	G	3₁₀ helix	trans	-52.1	-40	-179.3	-29.3	36.2	0	0	0	114.2	M271 C272	P269-M271 PolarHBondContact O-N 3.22Å; P269-C272 WeakPolarHBondContact O-CB 3.29Å; P269-C272 PolarHBondContact O-N 3Å; P269-C272 PolarHBondContact O-SG 3.19Å; P269-C272 VanDerWaalsContact O-SG 3.38Å
270	D	89.4	Confident	90.5	Very high	149 Å²	149	64.1 Å²	64.1	80%	0.797	31%	0.306	S	S	*	.	G	3₁₀ helix	trans	-66.7	-22.8	-179	-51.7	-42	0	0	0	113.1	S268	S268-D270 VanDerWaalsContact C-N 3.25Å; S268-D270 PolarHBondContact O-N 3.47Å
271	M	91.3	Very high	90.6	Very high	56 Å²	56	67.2 Å²	67.2	28%	0.276	33%	0.325	S	S	.	.	G	3₁₀ helix	trans	-92.4	-3.4	-178.1	-65.6	-61.9	-71.1	0	0	112.9	F266 S268 P269 E273 F274 N275	F266-M271 HydrophobicContact CB-CB 4.06Å; F266-M271 HydrophobicContact CB-CE 4.03Å; F266-M271 HydrophobicContact CB-CG 4.28Å; F266-M271 HydrophobicContact CD1-CE 4.36Å; F266-M271 HydrophobicContact CD2-CE 4.09Å; F266-M271 HydrophobicContact CG-CE 3.93Å; F266-M271 WeakPolarHBondContact O-CB 3.49Å; S268-M271 PolarHBondContact O-N 3.08Å; S268-M271 VanDerWaalsContact OG-CG 3.23Å; S268-M271 WeakPolarHBondContact OG-CG 3.47Å; P269-M271 PolarHBondContact O-N 3.22Å; M271-E273 PolarHBondContact O-N 2.85Å; M271-F274 HydrophobicContact CE-CB 4.34Å; M271-F274 HydrophobicContact CE-CD1 3.59Å; M271-F274 HydrophobicContact CE-CE1 4.08Å; M271-F274 HydrophobicContact CE-CG 4.05Å; M271-F274 WeakPolarHBondContact O-CB 3.24Å; M271-F274 PolarHBondContact O-N 3.03Å; M271-N275 VanDerWaalsContact O-CG 3.24Å; M271-N275 PolarHBondContact O-N 3.18Å; M271-N275 PolarHBondContact O-OD1 3.4Å
272	C	88.9	Confident	90.7	Very high	29 Å²	29	61.2 Å²	61.2	20%	0.196	30%	0.303	C	S	.	.	H	α-helix	trans	-66.9	-36.3	-174.4	-62.3	0	0	0	0	113.5	C19 P269 N275 N276	C19-C272 WeakPolarHBondContact CA-SG 3.49Å; C19-C272 HydrophobicContact CB-CB 3.8Å; C19-C272 WeakPolarHBondContact CB-SG 3.47Å; C19-C272 WeakPolarHBondContact SG-CA 3.47Å; C19-C272 WeakPolarHBondContact SG-CB 3.18Å; C19-C272 CovalentContact SG-SG 2.05Å; C19-C272 PolarHBondContact SG-SG 2.72Å; P269-C272 WeakPolarHBondContact O-CB 3.29Å; P269-C272 PolarHBondContact O-N 3Å; P269-C272 PolarHBondContact O-SG 3.19Å; P269-C272 VanDerWaalsContact O-SG 3.38Å; C272-N275 PolarHBondContact O-N 3.36Å; C272-N276 VanDerWaalsContact O-CG 3.27Å; C272-N276 PolarHBondContact O-N 2.85Å; C272-N276 PolarHBondContact O-ND2 2.78Å
273	E	90.1	Very high	90.8	Very high	118 Å²	118	61.3 Å²	61.3	55%	0.551	30%	0.303	S	S	*	.	H	α-helix	trans	-65.7	-43.7	174	-166.5	-172.8	161.5	0	0	111.2	M271 N275 N276 R277	M271-E273 PolarHBondContact O-N 2.85Å; E273-N275 VanDerWaalsContact C-N 3.35Å; E273-N275 PolarHBondContact O-N 3.5Å; E273-N276 PolarHBondContact O-N 2.91Å; E273-R277 WeakPolarHBondContact O-CG 3.22Å; E273-R277 PolarHBondContact O-N 2.86Å; E273-R277 IonicContact OE1-CZ 3.94Å; E273-R277 IonicContact OE1-NE 3.33Å; E273-R277 PolarHBondContact OE1-NE 2.96Å; E273-R277 IonicContact OE1-NH2 3.38Å; E273-R277 PolarHBondContact OE1-NH2 2.57Å
274	F	92.1	Very high	91.1	Very high	80 Å²	80	61.4 Å²	61.4	35%	0.351	31%	0.309	S	S	.	.	H	α-helix	trans	-57.9	-46.7	174.1	173.8	-98.3	0	0	0	111.4	L258 F266 M271 N276 R277 V278	L258-F274 HydrophobicContact CD1-CZ 4.3Å; L258-F274 HydrophobicContact CD2-CZ 4.39Å; F266-F274 HydrophobicContact CD2-CD1 4.45Å; F266-F274 AromaticContact CD2-CE1 3.94Å; F266-F274 HydrophobicContact CD2-CE1 3.94Å; F266-F274 HydrophobicContact CE2-CE1 4.26Å; M271-F274 HydrophobicContact CE-CB 4.34Å; M271-F274 HydrophobicContact CE-CD1 3.59Å; M271-F274 HydrophobicContact CE-CE1 4.08Å; M271-F274 HydrophobicContact CE-CG 4.05Å; M271-F274 WeakPolarHBondContact O-CB 3.24Å; M271-F274 PolarHBondContact O-N 3.03Å; F274-N276 VanDerWaalsContact C-N 3.32Å; F274-N276 PolarHBondContact O-N 3.44Å; F274-R277 PolarHBondContact O-N 2.97Å; F274-R277 VanDerWaalsContact O-N 3.15Å; F274-V278 HydrophobicContact CD1-CG2 4Å; F274-V278 HydrophobicContact CD2-CG2 4.31Å; F274-V278 HydrophobicContact CE1-CG2 3.56Å; F274-V278 HydrophobicContact CE2-CG2 3.89Å; F274-V278 HydrophobicContact CG-CG2 4.37Å; F274-V278 HydrophobicContact CZ-CG2 3.5Å; F274-V278 VanDerWaalsContact CZ-CG2 3.5Å; F274-V278 WeakPolarHBondContact O-CG2 3.23Å; F274-V278 PolarHBondContact O-N 2.82Å
275	N	91.1	Very high	91.4	Very high	5 Å²	5	59.7 Å²	59.7	3%	0.027	30%	0.3	C	S	.	.	H	α-helix	trans	-61.3	-39.5	178	-70.5	-6.2	0	0	0	112.5	A262 F266 Q267 M271 C272 E273 V278 Y279	A262-N275 WeakPolarHBondContact CB-OD1 3.32Å; F266-N275 PolarHBondContact O-ND2 3.32Å; Q267-N275 PolarHBondContact NE2-ND2 3.44Å; M271-N275 VanDerWaalsContact O-CG 3.24Å; M271-N275 PolarHBondContact O-N 3.18Å; M271-N275 PolarHBondContact O-OD1 3.4Å; C272-N275 PolarHBondContact O-N 3.36Å; E273-N275 VanDerWaalsContact C-N 3.35Å; E273-N275 PolarHBondContact O-N 3.5Å; N275-V278 PolarHBondContact O-N 3.02Å; N275-Y279 WeakPolarHBondContact O-CB 3.35Å; N275-Y279 PolarHBondContact O-N 3.48Å
276	N	90.3	Very high	91.6	Very high	38 Å²	38	53 Å²	53	20%	0.203	27%	0.274	C	S	.	.	H	α-helix	trans	-62.6	-43.3	175.2	-73.5	-31.1	0	0	0	111.2	L21 T22 C272 E273 F274 Y279 A280	L21-N276 WeakPolarHBondContact CA-OD1 3.3Å; T22-N276 PolarHBondContact N-OD1 3.42Å; C272-N276 VanDerWaalsContact O-CG 3.27Å; C272-N276 PolarHBondContact O-N 2.85Å; C272-N276 PolarHBondContact O-ND2 2.78Å; E273-N276 PolarHBondContact O-N 2.91Å; F274-N276 VanDerWaalsContact C-N 3.32Å; F274-N276 PolarHBondContact O-N 3.44Å; N276-Y279 PolarHBondContact O-N 2.91Å; N276-A280 WeakPolarHBondContact O-CB 3.38Å; N276-A280 PolarHBondContact O-N 3.26Å
277	R	92.6	Very high	91.8	Very high	161 Å²	161	50.4 Å²	50.4	61%	0.608	26%	0.262	S	S	*	.	H	α-helix	trans	-64.8	-45.4	175.8	-67.1	177.2	-175.8	-158.3	2.4	111.6	E273 F274 Y279 A280 T281	E273-R277 WeakPolarHBondContact O-CG 3.22Å; E273-R277 PolarHBondContact O-N 2.86Å; E273-R277 IonicContact OE1-CZ 3.94Å; E273-R277 IonicContact OE1-NE 3.33Å; E273-R277 PolarHBondContact OE1-NE 2.96Å; E273-R277 IonicContact OE1-NH2 3.38Å; E273-R277 PolarHBondContact OE1-NH2 2.57Å; F274-R277 PolarHBondContact O-N 2.97Å; F274-R277 VanDerWaalsContact O-N 3.15Å; R277-Y279 VanDerWaalsContact C-N 3.33Å; R277-Y279 PolarHBondContact O-N 3.41Å; R277-A280 PolarHBondContact O-N 2.89Å; R277-T281 WeakPolarHBondContact O-CB 3.44Å; R277-T281 PolarHBondContact O-N 3.39Å; R277-T281 PolarHBondContact O-OG1 2.87Å; R277-T281 VanDerWaalsContact O-OG1 3.06Å
278	V	93.8	Very high	92	Very high	7 Å²	7	49.4 Å²	49.4	4%	0.042	26%	0.259	C	S	.	.	H	α-helix	trans	-58.3	-46.2	176.2	167.2	0	0	0	0	111	M255 L258 N259 A262 F274 N275 T281 Y282	M255-V278 HydrophobicContact CE-CB 4.35Å; M255-V278 HydrophobicContact CE-CG1 3.97Å; M255-V278 VanDerWaalsContact CE-O 3.31Å; M255-V278 WeakPolarHBondContact CE-O 3.23Å; L258-V278 HydrophobicContact CB-CG1 4.38Å; L258-V278 HydrophobicContact CD2-CG1 4.28Å; L258-V278 HydrophobicContact CD2-CG2 3.86Å; L258-V278 HydrophobicContact CG-CG1 3.89Å; L258-V278 HydrophobicContact CG-CG2 4.05Å; N259-V278 VanDerWaalsContact CA-CG1 3.49Å; N259-V278 HydrophobicContact CB-CG1 3.86Å; A262-V278 HydrophobicContact CB-CG1 4.41Å; F274-V278 HydrophobicContact CD1-CG2 4Å; F274-V278 HydrophobicContact CD2-CG2 4.31Å; F274-V278 HydrophobicContact CE1-CG2 3.56Å; F274-V278 HydrophobicContact CE2-CG2 3.89Å; F274-V278 HydrophobicContact CG-CG2 4.37Å; F274-V278 HydrophobicContact CZ-CG2 3.5Å; F274-V278 VanDerWaalsContact CZ-CG2 3.5Å; F274-V278 WeakPolarHBondContact O-CG2 3.23Å; F274-V278 PolarHBondContact O-N 2.82Å; N275-V278 PolarHBondContact O-N 3.02Å; V278-T281 PolarHBondContact O-N 3.4Å; V278-Y282 VanDerWaalsContact O-CB 3.29Å; V278-Y282 WeakPolarHBondContact O-CB 3.32Å; V278-Y282 PolarHBondContact O-N 3.04Å
279	Y	91.4	Very high	92.3	Very high	37 Å²	37	47 Å²	47	15%	0.145	24%	0.242	C	C	.	.	H	α-helix	trans	-63.6	-43.8	177.4	175.6	-104	0	0	0	112.2	L21 K23 Q27 N275 N276 R277 Y282 Q283	L21-Y279 HydrophobicContact CD1-CG 4.42Å; L21-Y279 HydrophobicContact CD2-CD1 3.64Å; L21-Y279 HydrophobicContact CD2-CD2 3.6Å; L21-Y279 HydrophobicContact CD2-CE1 3.81Å; L21-Y279 HydrophobicContact CD2-CE2 3.76Å; L21-Y279 HydrophobicContact CD2-CG 3.52Å; L21-Y279 HydrophobicContact CG-CD1 4.29Å; L21-Y279 HydrophobicContact CG-CG 4.24Å; K23-Y279 HydrophobicContact CG-CE1 4.35Å; Q27-Y279 PolarHBondContact OE1-OH 3.48Å; N275-Y279 WeakPolarHBondContact O-CB 3.35Å; N275-Y279 PolarHBondContact O-N 3.48Å; N276-Y279 PolarHBondContact O-N 2.91Å; R277-Y279 VanDerWaalsContact C-N 3.33Å; R277-Y279 PolarHBondContact O-N 3.41Å; Y279-Y282 WeakPolarHBondContact O-CB 3.29Å; Y279-Y282 PolarHBondContact O-N 3.32Å; Y279-Q283 HydrophobicContact CE1-CG 4.18Å; Y279-Q283 VanDerWaalsContact CZ-NE2 3.35Å; Y279-Q283 WeakPolarHBondContact O-CG 3.4Å; Y279-Q283 PolarHBondContact O-N 3.32Å
280	A	92	Very high	92.6	Very high	22 Å²	22	42.4 Å²	42.4	18%	0.182	21%	0.212	C	C	.	.	H	α-helix	trans	-61.2	-48.7	177.5	0	0	0	0	0	111.2	F26 N276 R277 Y282 Q283 V284	F26-A280 HydrophobicContact CE1-CB 3.82Å; F26-A280 HydrophobicContact CZ-CB 3.92Å; N276-A280 WeakPolarHBondContact O-CB 3.38Å; N276-A280 PolarHBondContact O-N 3.26Å; R277-A280 PolarHBondContact O-N 2.89Å; A280-Y282 VanDerWaalsContact C-N 3.3Å; A280-Y282 PolarHBondContact O-N 3.27Å; A280-Q283 WeakPolarHBondContact O-CB 3.5Å; A280-Q283 PolarHBondContact O-N 3.26Å; A280-Q283 VanDerWaalsContact O-N 3.07Å; A280-V284 PolarHBondContact O-N 2.96Å; A280-V284 VanDerWaalsContact O-N 3.16Å
281	T	94.9	Very high	92.6	Very high	66 Å²	66	37.3 Å²	37.3	41%	0.405	19%	0.185	S	C	.	.	H	α-helix	trans	-63.7	-36.3	176.8	-55.8	0	0	0	0	111.5	M255 R277 V278 Q283 V284 T285	M255-T281 HydrophobicContact CE-CG2 3.76Å; M255-T281 HydrophobicContact CG-CG2 3.99Å; M255-T281 HydrophobicContact SD-CG2 3.8Å; R277-T281 WeakPolarHBondContact O-CB 3.44Å; R277-T281 PolarHBondContact O-N 3.39Å; R277-T281 PolarHBondContact O-OG1 2.87Å; R277-T281 VanDerWaalsContact O-OG1 3.06Å; V278-T281 PolarHBondContact O-N 3.4Å; T281-Q283 VanDerWaalsContact C-N 3.33Å; T281-Q283 PolarHBondContact O-N 3.35Å; T281-V284 WeakPolarHBondContact O-CB 3.22Å; T281-V284 PolarHBondContact O-N 3.31Å; T281-V284 VanDerWaalsContact O-N 3.14Å; T281-T285 WeakPolarHBondContact O-CG2 3.45Å; T281-T285 PolarHBondContact O-N 3.06Å; T281-T285 PolarHBondContact O-OG1 3.34Å
282	Y	94.4	Very high	92.4	Very high	7 Å²	7	34.7 Å²	34.7	3%	0.027	17%	0.172	C	C	.	.	H	α-helix	trans	-60.2	-40	171.7	174	-123.5	0	0	0	112.4	D180 F252 M255 K256 N259 V278 Y279 A280 V284 T285 R286	D180-Y282 PolarHBondContact OD2-OH 3.44Å; F252-Y282 HydrophobicContact CD2-CE2 4.34Å; F252-Y282 AromaticContact CE2-CE2 3.96Å; F252-Y282 HydrophobicContact CE2-CE2 3.96Å; M255-Y282 HydrophobicContact CB-CD2 4.2Å; K256-Y282 HydrophobicContact CB-CD2 4.32Å; K256-Y282 HydrophobicContact CB-CE2 3.72Å; K256-Y282 HydrophobicContact CG-CE2 4.2Å; N259-Y282 HydrophobicContact CB-CD1 4.24Å; N259-Y282 HydrophobicContact CB-CG 4.13Å; V278-Y282 VanDerWaalsContact O-CB 3.29Å; V278-Y282 WeakPolarHBondContact O-CB 3.32Å; V278-Y282 PolarHBondContact O-N 3.04Å; Y279-Y282 WeakPolarHBondContact O-CB 3.29Å; Y279-Y282 PolarHBondContact O-N 3.32Å; A280-Y282 VanDerWaalsContact C-N 3.3Å; A280-Y282 PolarHBondContact O-N 3.27Å; Y282-V284 VanDerWaalsContact C-N 3.3Å; Y282-V284 PolarHBondContact O-N 2.88Å; Y282-T285 PolarHBondContact O-N 2.86Å; Y282-T285 PolarHBondContact O-OG1 3.29Å; Y282-R286 HydrophobicContact CD2-CG 4.05Å; Y282-R286 VanDerWaalsContact CE1-CD 3.46Å; Y282-R286 HydrophobicContact CE1-CG 4.32Å; Y282-R286 HydrophobicContact CE2-CG 3.62Å; Y282-R286 WeakPolarHBondContact O-CD 3.41Å; Y282-R286 WeakPolarHBondContact O-CG 3.3Å; Y282-R286 PolarHBondContact O-N 2.78Å; Y282-R286 PolarHBondContact OH-NE 3.45Å
283	Q	93.4	Very high	92.4	Very high	4 Å²	4	33.3 Å²	33.3	2%	0.019	16%	0.163	C	C	.	.	H	α-helix	trans	-62.2	-39.6	173.6	-60.9	-46.6	-51.5	0	0	111.9	F26 Q27 L31 Y279 A280 T281 R286 G287	F26-Q283 HydrophobicContact CE2-CB 4.5Å; F26-Q283 HydrophobicContact CZ-CB 4.1Å; Q27-Q283 HydrophobicContact CB-CB 4.4Å; Q27-Q283 HydrophobicContact CB-CG 4.15Å; L31-Q283 HydrophobicContact CD1-CB 4.32Å; L31-Q283 WeakPolarHBondContact CD2-O 3.41Å; Y279-Q283 HydrophobicContact CE1-CG 4.18Å; Y279-Q283 VanDerWaalsContact CZ-NE2 3.35Å; Y279-Q283 WeakPolarHBondContact O-CG 3.4Å; Y279-Q283 PolarHBondContact O-N 3.32Å; A280-Q283 WeakPolarHBondContact O-CB 3.5Å; A280-Q283 PolarHBondContact O-N 3.26Å; A280-Q283 VanDerWaalsContact O-N 3.07Å; T281-Q283 VanDerWaalsContact C-N 3.33Å; T281-Q283 PolarHBondContact O-N 3.35Å; Q283-R286 PolarHBondContact O-N 3Å; Q283-G287 PolarHBondContact O-N 3.29Å
284	V	95.1	Very high	92.1	Very high	53 Å²	53	28.8 Å²	28.8	32%	0.321	14%	0.144	S	C	.	.	H	α-helix	trans	-61.8	-50.8	175.8	177.6	0	0	0	0	110.8	F26 Y30 A280 T281 Y282 R286 G287 L288	F26-V284 HydrophobicContact CE2-CG2 4.13Å; Y30-V284 HydrophobicContact CE1-CB 4.45Å; Y30-V284 HydrophobicContact CE1-CG2 4.44Å; Y30-V284 PolarHBondContact OH-O 3.26Å; Y30-V284 VanDerWaalsContact OH-O 3.06Å; A280-V284 PolarHBondContact O-N 2.96Å; A280-V284 VanDerWaalsContact O-N 3.16Å; T281-V284 WeakPolarHBondContact O-CB 3.22Å; T281-V284 PolarHBondContact O-N 3.31Å; T281-V284 VanDerWaalsContact O-N 3.14Å; Y282-V284 VanDerWaalsContact C-N 3.3Å; Y282-V284 PolarHBondContact O-N 2.88Å; V284-R286 VanDerWaalsContact C-N 3.26Å; V284-R286 PolarHBondContact O-N 3.42Å; V284-G287 WeakPolarHBondContact O-CA 3.47Å; V284-G287 PolarHBondContact O-N 3.41Å; V284-L288 HydrophobicContact CG1-CD1 4.36Å; V284-L288 PolarHBondContact O-N 3.06Å
285	T	95.9	Very high	91.6	Very high	6 Å²	6	26.9 Å²	26.9	4%	0.037	14%	0.139	C	C	.	.	H	α-helix	trans	-67.4	-25.7	-177.2	62.3	0	0	0	0	113.5	P251 M255 T281 Y282 L288 A289	P251-T285 HydrophobicContact CB-CG2 3.51Å; M255-T285 HydrophobicContact CB-CG2 4.23Å; M255-T285 WeakPolarHBondContact CB-OG1 3.34Å; M255-T285 HydrophobicContact CG-CG2 3.7Å; T281-T285 WeakPolarHBondContact O-CG2 3.45Å; T281-T285 PolarHBondContact O-N 3.06Å; T281-T285 PolarHBondContact O-OG1 3.34Å; Y282-T285 PolarHBondContact O-N 2.86Å; Y282-T285 PolarHBondContact O-OG1 3.29Å; T285-L288 PolarHBondContact O-N 3.17Å; T285-A289 WeakPolarHBondContact O-CB 3.29Å; T285-A289 PolarHBondContact O-N 2.89Å
286	R	93.6	Very high	90.9	Very high	8 Å²	8	26.6 Å²	26.6	3%	0.03	14%	0.137	C	C	.	.	H	α-helix	trans	-64.2	-40.7	168.7	-72.2	167.5	94	-121.5	-16.5	112.7	Y88 D180 F252 Y282 Q283 V284 S290	Y88-R286 PolarHBondContact OH-NH1 3.07Å; D180-R286 IonicContact OD1-CZ 2.7Å; D180-R286 IonicContact OD1-NE 2.85Å; D180-R286 IonicContact OD1-NH2 3.76Å; D180-R286 PolarHBondContact OD1-NH2 3.33Å; D180-R286 IonicContact OD2-CZ 2.81Å; D180-R286 VanDerWaalsContact OD2-CZ 3.31Å; D180-R286 IonicContact OD2-NE 3.19Å; D180-R286 PolarHBondContact OD2-NE 3.39Å; D180-R286 IonicContact OD2-NH2 3.31Å; D180-R286 PolarHBondContact OD2-NH2 2.94Å; F252-R286 HydrophobicContact CD2-CG 4.07Å; F252-R286 HydrophobicContact CE2-CG 3.84Å; Y282-R286 HydrophobicContact CD2-CG 4.05Å; Y282-R286 VanDerWaalsContact CE1-CD 3.46Å; Y282-R286 HydrophobicContact CE1-CG 4.32Å; Y282-R286 HydrophobicContact CE2-CG 3.62Å; Y282-R286 WeakPolarHBondContact O-CD 3.41Å; Y282-R286 WeakPolarHBondContact O-CG 3.3Å; Y282-R286 PolarHBondContact O-N 2.78Å; Y282-R286 PolarHBondContact OH-NE 3.45Å; Q283-R286 PolarHBondContact O-N 3Å; V284-R286 VanDerWaalsContact C-N 3.26Å; V284-R286 PolarHBondContact O-N 3.42Å; R286-S290 PolarHBondContact O-N 2.96Å
287	G	94.4	Very high	90.2	Very high	0 Å²	0	25.1 Å²	25.1	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-61	-48.5	171.8	0	0	0	0	0	110.6	Q283 V284 A289 S290 L291	Q283-G287 PolarHBondContact O-N 3.29Å; V284-G287 WeakPolarHBondContact O-CA 3.47Å; V284-G287 PolarHBondContact O-N 3.41Å; G287-A289 PolarHBondContact O-N 2.93Å; G287-S290 PolarHBondContact O-N 2.95Å; G287-S290 VanDerWaalsContact O-N 3.11Å; G287-S290 PolarHBondContact O-OG 3.48Å; G287-L291 PolarHBondContact O-N 3.07Å
288	L	93.8	Very high	89.1	Confident	42 Å²	42	21.4 Å²	21.4	22%	0.22	12%	0.121	C	C	.	.	H	α-helix	trans	-59.9	-42	177.9	-61.6	177.6	0	0	0	112.8	V247 S248 V284 T285 S290 L291	V247-L288 WeakPolarHBondContact O-CD1 3.06Å; S248-L288 WeakPolarHBondContact CB-O 3.48Å; S248-L288 PolarHBondContact OG-O 3.48Å; V284-L288 HydrophobicContact CG1-CD1 4.36Å; V284-L288 PolarHBondContact O-N 3.06Å; T285-L288 PolarHBondContact O-N 3.17Å; L288-S290 PolarHBondContact O-N 3.44Å; L288-L291 HydrophobicContact CD2-CD1 3.77Å; L288-L291 WeakPolarHBondContact O-CB 3.43Å; L288-L291 PolarHBondContact O-N 3.4Å
289	A	93.5	Very high	87.9	Confident	3 Å²	3	21.3 Å²	21.3	3%	0.025	12%	0.12	C	C	.	.	H	α-helix	trans	-56	-36.1	176	0	0	0	0	0	112.7	F108 F252 T285 G287 L291 N292	F108-A289 HydrophobicContact CZ-CB 4.37Å; F252-A289 HydrophobicContact CB-CB 3.99Å; F252-A289 HydrophobicContact CD2-CB 3.98Å; F252-A289 HydrophobicContact CG-CB 3.91Å; T285-A289 WeakPolarHBondContact O-CB 3.29Å; T285-A289 PolarHBondContact O-N 2.89Å; G287-A289 PolarHBondContact O-N 2.93Å; A289-L291 VanDerWaalsContact C-N 3.32Å; A289-L291 PolarHBondContact O-N 3.44Å; A289-N292 WeakPolarHBondContact O-CB 3.45Å
290	S	93	Very high	86.9	Confident	0 Å²	0	19.7 Å²	19.7	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-72.7	-21.4	178.4	71.2	0	0	0	0	114.3	Y35 V38 Y77 R286 G287 L288 N292 S293	Y35-S290 WeakPolarHBondContact CE1-OG 3.09Å; V38-S290 VanDerWaalsContact CG1-O 3.31Å; V38-S290 WeakPolarHBondContact CG1-O 3.39Å; Y77-S290 WeakPolarHBondContact OH-CB 3.3Å; R286-S290 PolarHBondContact O-N 2.96Å; G287-S290 PolarHBondContact O-N 2.95Å; G287-S290 VanDerWaalsContact O-N 3.11Å; G287-S290 PolarHBondContact O-OG 3.48Å; L288-S290 PolarHBondContact O-N 3.44Å; S290-N292 PolarHBondContact O-N 2.84Å; S290-S293 PolarHBondContact O-N 3.27Å
291	L	90.1	Very high	85.7	Confident	41 Å²	41	21 Å²	21	22%	0.215	12%	0.115	C	C	.	.	H	α-helix	trans	-65.9	-21.7	178.1	-64.8	174.4	0	0	0	112.6	V34 M37 V38 G287 L288 A289 S293 C294 V295	V34-L291 HydrophobicContact CG1-CD2 4.14Å; V34-L291 HydrophobicContact CG1-CG 4.49Å; M37-L291 HydrophobicContact CE-CD2 3.2Å; V38-L291 HydrophobicContact CG2-CD2 3.75Å; G287-L291 PolarHBondContact O-N 3.07Å; L288-L291 HydrophobicContact CD2-CD1 3.77Å; L288-L291 WeakPolarHBondContact O-CB 3.43Å; L288-L291 PolarHBondContact O-N 3.4Å; A289-L291 VanDerWaalsContact C-N 3.32Å; A289-L291 PolarHBondContact O-N 3.44Å; L291-S293 PolarHBondContact O-N 2.99Å; L291-C294 WeakPolarHBondContact O-CB 3.29Å; L291-C294 PolarHBondContact O-N 3.5Å; L291-V295 PolarHBondContact O-N 3.29Å
292	N	86.8	Confident	84.2	Confident	1 Å²	1	21.3 Å²	21.3	1%	0.005	11%	0.114	C	C	.	.	H	α-helix	trans	-48.9	-46.3	176.9	176.5	76.6	0	0	0	111.9	V244 Y249 A289 S290 C294 V295 D296	V244-N292 WeakPolarHBondContact CG1-OD1 3.47Å; Y249-N292 HydrophobicContact CE1-CB 4.07Å; Y249-N292 PolarHBondContact OH-ND2 2.96Å; Y249-N292 PolarHBondContact OH-OD1 3.01Å; A289-N292 WeakPolarHBondContact O-CB 3.45Å; S290-N292 PolarHBondContact O-N 2.84Å; N292-C294 PolarHBondContact O-N 3.25Å; N292-V295 PolarHBondContact O-N 3.04Å; N292-D296 PolarHBondContact ND2-OD2 2.86Å; N292-D296 PolarHBondContact O-N 2.82Å; N292-D296 PolarHBondContact OD1-OD2 3.41Å
293	S	88.6	Confident	82.3	Confident	0 Å²	0	21.3 Å²	21.3	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-64.4	-10.9	-178.2	-58.9	0	0	0	0	114.7	N46 D74 Y77 S290 L291 P297	N46-S293 PolarHBondContact ND2-O 2.78Å; D74-S293 WeakPolarHBondContact OD1-CA 3.43Å; D74-S293 WeakPolarHBondContact OD1-CB 3.47Å; D74-S293 PolarHBondContact OD1-OG 2.64Å; Y77-S293 WeakPolarHBondContact CD1-OG 3.42Å; S290-S293 PolarHBondContact O-N 3.27Å; L291-S293 PolarHBondContact O-N 2.99Å; S293-P297 WeakPolarHBondContact O-CD 3.17Å
294	C	84.1	Confident	80.7	Confident	23 Å²	23	22 Å²	22	16%	0.155	12%	0.124	C	C	.	.	H	α-helix	trans	-98.6	-28.8	175	-50.6	0	0	0	0	112.4	V38 T41 L291 N292 P297	V38-C294 WeakPolarHBondContact CA-SG 3.36Å; T41-C294 PolarHBondContact OG1-SG 3.11Å; L291-C294 WeakPolarHBondContact O-CB 3.29Å; L291-C294 PolarHBondContact O-N 3.5Å; N292-C294 PolarHBondContact O-N 3.25Å; C294-P297 WeakPolarHBondContact O-CD 3.15Å
295	V	79.9	Confident	79	Confident	40 Å²	40	23 Å²	23	24%	0.242	13%	0.128	C	C	.	.	H	α-helix	trans	-81.1	-30.4	-179.6	-178.5	0	0	0	0	110.8	I240 V244 L291 N292 I298 L299	I240-V295 HydrophobicContact CG2-CG1 3.68Å; V244-V295 HydrophobicContact CG2-CB 4.11Å; V244-V295 HydrophobicContact CG2-CG1 3.58Å; L291-V295 PolarHBondContact O-N 3.29Å; N292-V295 PolarHBondContact O-N 3.04Å; V295-I298 WeakPolarHBondContact O-CA 3.26Å; V295-I298 WeakPolarHBondContact O-CB 3.2Å; V295-I298 PolarHBondContact O-N 2.74Å; V295-L299 PolarHBondContact O-N 3.4Å
296	D	77.8	Confident	77.3	Confident	0 Å²	0	26 Å²	26	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-60.4	-39.3	179.6	-72.7	-24	0	0	0	114.1	L70 D74 N292 I298 L299 Y300	L70-D296 HydrophobicContact CD2-CB 4.16Å; L70-D296 HydrophobicContact CG-CB 4.38Å; D74-D296 WeakPolarHBondContact OD2-CB 3.35Å; D74-D296 VanDerWaalsContact OD2-OD2 3.08Å; N292-D296 PolarHBondContact ND2-OD2 2.86Å; N292-D296 PolarHBondContact O-N 2.82Å; N292-D296 PolarHBondContact OD1-OD2 3.41Å; D296-I298 VanDerWaalsContact C-N 3.25Å; D296-I298 PolarHBondContact O-N 3.04Å; D296-L299 WeakPolarHBondContact O-CA 3.23Å; D296-L299 VanDerWaalsContact O-CB 3.23Å; D296-L299 WeakPolarHBondContact O-CB 3.45Å; D296-L299 PolarHBondContact O-N 2.73Å; D296-L299 WeakPolarHBondContact OD1-CD1 3.38Å; D296-Y300 WeakPolarHBondContact O-CD2 3.39Å; D296-Y300 WeakPolarHBondContact O-CE2 3.29Å; D296-Y300 PolarHBondContact O-N 2.71Å
297	P	75.1	Confident	75.9	Confident	7 Å²	7	25.8 Å²	25.8	5%	0.045	15%	0.145	C	C	.	.	H	α-helix	trans	-49.8	-42.8	166.6	-32.3	36.4	0	0	0	114.3	S293 C294 L299 Y300 F301	S293-P297 WeakPolarHBondContact O-CD 3.17Å; C294-P297 WeakPolarHBondContact O-CD 3.15Å; P297-L299 VanDerWaalsContact C-N 3.26Å; P297-L299 PolarHBondContact O-N 2.8Å; P297-Y300 VanDerWaalsContact CA-CD2 3.45Å; P297-Y300 HydrophobicContact CB-CD2 4.5Å; P297-Y300 WeakPolarHBondContact O-CB 3.33Å; P297-Y300 PolarHBondContact O-N 3.16Å; P297-F301 HydrophobicContact CB-CE2 4.21Å; P297-F301 WeakPolarHBondContact O-CD2 3.39Å; P297-F301 PolarHBondContact O-N 3.37Å; P297-F301 VanDerWaalsContact O-N 3.17Å
298	I	70.4	Confident	74.6	Confident	82 Å²	82	33.1 Å²	33.1	42%	0.421	17%	0.173	S	C	.	.	H	α-helix	trans	-62.1	-37.1	179.3	-56.3	174.6	0	0	0	110.4	I240 V295 D296 Y300 F301 L302	I240-I298 HydrophobicContact CD1-CG2 4.4Å; V295-I298 WeakPolarHBondContact O-CA 3.26Å; V295-I298 WeakPolarHBondContact O-CB 3.2Å; V295-I298 PolarHBondContact O-N 2.74Å; D296-I298 VanDerWaalsContact C-N 3.25Å; D296-I298 PolarHBondContact O-N 3.04Å; I298-Y300 VanDerWaalsContact C-N 3.29Å; I298-Y300 PolarHBondContact O-N 2.87Å; I298-F301 PolarHBondContact O-N 3.31Å; I298-L302 HydrophobicContact CG2-CD1 3.44Å; I298-L302 VanDerWaalsContact CG2-CD1 3.44Å; I298-L302 HydrophobicContact CG2-CG 3.93Å; I298-L302 WeakPolarHBondContact O-CB 3.49Å; I298-L302 WeakPolarHBondContact O-CG 3.48Å; I298-L302 PolarHBondContact O-N 3.3Å
299	L	68.2	Low	73.3	Confident	5 Å²	5	38.3 Å²	38.3	3%	0.026	19%	0.189	C	C	.	.	H	α-helix	trans	-58.7	-41	172.9	-66.2	175.4	0	0	0	111.7	L119 L237 I240 V241 V295 D296 P297 A303	L119-L299 HydrophobicContact CD2-CD1 3.82Å; L237-L299 HydrophobicContact CD1-CD2 3.62Å; I240-L299 HydrophobicContact CB-CD2 3.56Å; I240-L299 HydrophobicContact CD1-CD2 3.95Å; I240-L299 HydrophobicContact CG1-CD2 4.37Å; I240-L299 HydrophobicContact CG2-CD2 3.31Å; I240-L299 HydrophobicContact CG2-CG 3.88Å; V241-L299 HydrophobicContact CG2-CD1 4.22Å; V241-L299 HydrophobicContact CG2-CD2 4.26Å; V295-L299 PolarHBondContact O-N 3.4Å; D296-L299 WeakPolarHBondContact O-CA 3.23Å; D296-L299 VanDerWaalsContact O-CB 3.23Å; D296-L299 WeakPolarHBondContact O-CB 3.45Å; D296-L299 PolarHBondContact O-N 2.73Å; D296-L299 WeakPolarHBondContact OD1-CD1 3.38Å; P297-L299 VanDerWaalsContact C-N 3.26Å; P297-L299 PolarHBondContact O-N 2.8Å; L299-A303 WeakPolarHBondContact O-CB 3.45Å; L299-A303 PolarHBondContact O-N 3.48Å
300	Y	69.1	Low	72.3	Confident	3 Å²	3	41 Å²	41	1%	0.012	20%	0.201	C	C	.	.	H	α-helix	trans	-67.1	-42.3	-179.9	-47.5	-39	0	0	0	112.2	A49 M67 L70 A71 D296 P297 I298	A49-Y300 HydrophobicContact CB-CD2 3.6Å; A49-Y300 HydrophobicContact CB-CE2 3.95Å; M67-Y300 HydrophobicContact CB-CD1 3.82Å; M67-Y300 HydrophobicContact CB-CE1 3.72Å; M67-Y300 HydrophobicContact CG-CD1 3.9Å; M67-Y300 HydrophobicContact CG-CE1 3.97Å; M67-Y300 PolarHBondContact O-OH 3.29Å; M67-Y300 HydrophobicContact SD-CD1 4.18Å; L70-Y300 WeakPolarHBondContact CB-OH 3.46Å; L70-Y300 HydrophobicContact CD2-CE1 4.17Å; L70-Y300 WeakPolarHBondContact CD2-OH 3.48Å; L70-Y300 WeakPolarHBondContact CG-OH 3.43Å; A71-Y300 WeakPolarHBondContact CA-OH 3.44Å; A71-Y300 HydrophobicContact CB-CE2 3.85Å; A71-Y300 PolarHBondContact N-OH 3.21Å; D296-Y300 WeakPolarHBondContact O-CD2 3.39Å; D296-Y300 WeakPolarHBondContact O-CE2 3.29Å; D296-Y300 PolarHBondContact O-N 2.71Å; P297-Y300 VanDerWaalsContact CA-CD2 3.45Å; P297-Y300 HydrophobicContact CB-CD2 4.5Å; P297-Y300 WeakPolarHBondContact O-CB 3.33Å; P297-Y300 PolarHBondContact O-N 3.16Å; I298-Y300 VanDerWaalsContact C-N 3.29Å; I298-Y300 PolarHBondContact O-N 2.87Å
301	F	67.6	Low	71.4	Confident	50 Å²	50	42.7 Å²	42.7	22%	0.219	21%	0.209	C	C	.	.	H	α-helix	trans	-73.3	-41.7	-179.3	-65.3	-77	0	0	0	112.6	L48 P297 I298 F307 R308 L311	L48-F301 HydrophobicContact CD2-CE1 4.21Å; L48-F301 HydrophobicContact CD2-CZ 3.71Å; L48-F301 HydrophobicContact CG-CZ 4.22Å; P297-F301 HydrophobicContact CB-CE2 4.21Å; P297-F301 WeakPolarHBondContact O-CD2 3.39Å; P297-F301 PolarHBondContact O-N 3.37Å; P297-F301 VanDerWaalsContact O-N 3.17Å; I298-F301 PolarHBondContact O-N 3.31Å; F301-F307 AromaticContact CD1-CD1 3.73Å; F301-F307 HydrophobicContact CD1-CD1 3.73Å; F301-F307 AromaticContact CD1-CE1 3.56Å; F301-F307 HydrophobicContact CD1-CE1 3.56Å; F301-F307 AromaticContact CE1-CD1 3.97Å; F301-F307 HydrophobicContact CE1-CD1 3.97Å; F301-F307 AromaticContact CE1-CE1 3.3Å; F301-F307 HydrophobicContact CE1-CE1 3.3Å; F301-F307 HydrophobicContact CE1-CZ 4.19Å; F301-F307 HydrophobicContact CG-CE1 4.49Å; F301-F307 AromaticContact CZ-CE1 4Å; F301-F307 HydrophobicContact CZ-CE1 4Å; F301-F307 HydrophobicContact CZ-CZ 4.48Å; F301-R308 WeakPolarHBondContact O-CD 3.39Å; F301-R308 VanDerWaalsContact O-CG 3.27Å; F301-R308 WeakPolarHBondContact O-CG 3.48Å; F301-L311 HydrophobicContact CD1-CD2 4.21Å; F301-L311 HydrophobicContact CE1-CD2 3.74Å
302	L	63.6	Low	70.6	Confident	73 Å²	73	43.3 Å²	43.3	38%	0.382	22%	0.217	S	C	.	.	H	α-helix	trans	-82.8	-34.6	-176	-65.7	-177.5	0	0	0	113.1	I240 I298 G304	I240-L302 HydrophobicContact CD1-CD1 3.84Å; I298-L302 HydrophobicContact CG2-CD1 3.44Å; I298-L302 VanDerWaalsContact CG2-CD1 3.44Å; I298-L302 HydrophobicContact CG2-CG 3.93Å; I298-L302 WeakPolarHBondContact O-CB 3.49Å; I298-L302 WeakPolarHBondContact O-CG 3.48Å; I298-L302 PolarHBondContact O-N 3.3Å; L302-G304 VanDerWaalsContact C-N 3.28Å; L302-G304 PolarHBondContact O-N 2.94Å
303	A	54.7	Low	70	Confident	7 Å²	7	51.6 Å²	51.6	6%	0.058	25%	0.248	C	C	.	.	S	Bend	trans	-80.9	-6.6	-179.6	0	0	0	0	0	113.6	M67 L299	M67-A303 HydrophobicContact CE-CB 4.24Å; L299-A303 WeakPolarHBondContact O-CB 3.45Å; L299-A303 PolarHBondContact O-N 3.48Å
304	G	60.3	Low	69.3	Low	18 Å²	18	51.8 Å²	51.8	19%	0.186	25%	0.25	C	C	.	.			trans	-130.5	88.1	-173.8	0	0	0	0	0	114.8	L302 T306 F307 R308	L302-G304 VanDerWaalsContact C-N 3.28Å; L302-G304 PolarHBondContact O-N 2.94Å; G304-T306 PolarHBondContact O-N 3.3Å; G304-T306 VanDerWaalsContact O-N 3.11Å; G304-F307 WeakPolarHBondContact O-CA 3.3Å; G304-F307 WeakPolarHBondContact O-CB 3.28Å; G304-F307 PolarHBondContact O-N 3.29Å; G304-R308 PolarHBondContact O-N 3.48Å; G304-R308 VanDerWaalsContact O-N 3.09Å
305	D	57.6	Low	68.9	Low	75 Å²	75	54.1 Å²	54.1	40%	0.401	26%	0.263	S	S	.	.	H	α-helix	trans	-53.7	-33.3	167.7	-68.9	-5.6	0	0	0	112.3	K233 F307 R308 R309	K233-D305 WeakPolarHBondContact CE-OD1 3.35Å; K233-D305 WeakPolarHBondContact CE-OD2 3.31Å; K233-D305 IonicContact NZ-OD1 3.3Å; K233-D305 IonicContact NZ-OD2 2.66Å; K233-D305 PolarHBondContact NZ-OD2 3.46Å; D305-F307 VanDerWaalsContact C-N 3.29Å; D305-F307 PolarHBondContact O-N 2.81Å; D305-R308 PolarHBondContact O-N 3.06Å; D305-R309 VanDerWaalsContact O-CB 3.29Å; D305-R309 WeakPolarHBondContact O-CB 3.28Å; D305-R309 PolarHBondContact O-N 2.89Å
306	T	61.7	Low	68.6	Low	68 Å²	68	59 Å²	59	42%	0.417	28%	0.281	S	S	.	.	H	α-helix	trans	-63.3	-36.5	173.7	-51.9	0	0	0	0	111.8	G304 K310	G304-T306 PolarHBondContact O-N 3.3Å; G304-T306 VanDerWaalsContact O-N 3.11Å; T306-K310 HydrophobicContact CG2-CD 4.15Å; T306-K310 VanDerWaalsContact O-CB 3.24Å; T306-K310 WeakPolarHBondContact O-CB 3.46Å; T306-K310 VanDerWaalsContact O-CG 3.24Å; T306-K310 WeakPolarHBondContact O-CG 3.37Å; T306-K310 PolarHBondContact O-N 3.24Å
307	F	63.6	Low	67.9	Low	4 Å²	4	66.7 Å²	66.7	2%	0.018	32%	0.315	C	S	.	.	H	α-helix	trans	-66.5	-51.7	175.5	-165.9	-75.9	0	0	0	110.2	M52 M57 F301 G304 D305 R309 K310 L311	M52-F307 HydrophobicContact CB-CE1 4.22Å; M52-F307 HydrophobicContact CB-CE2 3.48Å; M52-F307 VanDerWaalsContact CB-CE2 3.48Å; M52-F307 HydrophobicContact CB-CZ 3.31Å; M52-F307 HydrophobicContact CE-CD1 4.35Å; M52-F307 HydrophobicContact CE-CE1 4.15Å; M52-F307 HydrophobicContact CE-CE2 4.46Å; M52-F307 HydrophobicContact CE-CZ 4.24Å; M52-F307 HydrophobicContact CG-CE1 3.9Å; M52-F307 HydrophobicContact CG-CE2 4.11Å; M52-F307 HydrophobicContact CG-CZ 3.44Å; M52-F307 VanDerWaalsContact CG-CZ 3.44Å; M57-F307 HydrophobicContact CE-CD2 4.17Å; M57-F307 HydrophobicContact SD-CD2 3.36Å; M57-F307 WeakPolarHBondContact SD-CD2 3.44Å; M57-F307 HydrophobicContact SD-CE2 3.8Å; M57-F307 HydrophobicContact SD-CG 4.41Å; F301-F307 AromaticContact CD1-CD1 3.73Å; F301-F307 HydrophobicContact CD1-CD1 3.73Å; F301-F307 AromaticContact CD1-CE1 3.56Å; F301-F307 HydrophobicContact CD1-CE1 3.56Å; F301-F307 AromaticContact CE1-CD1 3.97Å; F301-F307 HydrophobicContact CE1-CD1 3.97Å; F301-F307 AromaticContact CE1-CE1 3.3Å; F301-F307 HydrophobicContact CE1-CE1 3.3Å; F301-F307 HydrophobicContact CE1-CZ 4.19Å; F301-F307 HydrophobicContact CG-CE1 4.49Å; F301-F307 AromaticContact CZ-CE1 4Å; F301-F307 HydrophobicContact CZ-CE1 4Å; F301-F307 HydrophobicContact CZ-CZ 4.48Å; G304-F307 WeakPolarHBondContact O-CA 3.3Å; G304-F307 WeakPolarHBondContact O-CB 3.28Å; G304-F307 PolarHBondContact O-N 3.29Å; D305-F307 VanDerWaalsContact C-N 3.29Å; D305-F307 PolarHBondContact O-N 2.81Å; F307-R309 PolarHBondContact O-N 3.34Å; F307-K310 PolarHBondContact O-N 2.87Å; F307-L311 WeakPolarHBondContact O-CB 3.33Å; F307-L311 PolarHBondContact O-N 2.95Å
308	R	66.5	Low	67.2	Low	153 Å²	153	70.4 Å²	70.4	58%	0.577	34%	0.338	S	S	*	.	H	α-helix	trans	-57.9	-46.2	178.1	-62.7	179.7	79.9	-170.9	6	112	F301 G304 D305 K310 L311 S312	F301-R308 WeakPolarHBondContact O-CD 3.39Å; F301-R308 VanDerWaalsContact O-CG 3.27Å; F301-R308 WeakPolarHBondContact O-CG 3.48Å; G304-R308 PolarHBondContact O-N 3.48Å; G304-R308 VanDerWaalsContact O-N 3.09Å; D305-R308 PolarHBondContact O-N 3.06Å; R308-K310 PolarHBondContact O-N 3.32Å; R308-L311 PolarHBondContact O-N 3.19Å; R308-S312 PolarHBondContact O-N 3.25Å
309	R	67.8	Low	66.9	Low	151 Å²	151	69.9 Å²	69.9	57%	0.57	34%	0.341	S	S	*	.	H	α-helix	trans	-63.7	-41.6	178	-174.9	174.3	63.4	178.4	-1.3	112.1	D305 F307 R313	D305-R309 VanDerWaalsContact O-CB 3.29Å; D305-R309 WeakPolarHBondContact O-CB 3.28Å; D305-R309 PolarHBondContact O-N 2.89Å; F307-R309 PolarHBondContact O-N 3.34Å; R309-R313 WeakPolarHBondContact O-CG 3.44Å; R309-R313 PolarHBondContact O-N 3.28Å; R309-R313 VanDerWaalsContact O-N 3.14Å
310	K	72.1	Confident	66.4	Low	60 Å²	60	79 Å²	79	26%	0.261	38%	0.375	S	S	.	.	H	α-helix	trans	-70	-37.4	177.2	-77.7	-177.6	164.6	-159.8	0	111.9	M52 H56 M57 T306 F307 R308 R313 A314	M52-K310 HydrophobicContact CE-CB 3.94Å; H56-K310 VanDerWaalsContact O-CD 3.26Å; H56-K310 WeakPolarHBondContact O-CD 3.36Å; H56-K310 WeakPolarHBondContact O-CE 3.33Å; H56-K310 PolarHBondContact O-NZ 2.81Å; M57-K310 HydrophobicContact CG-CD 4.4Å; T306-K310 HydrophobicContact CG2-CD 4.15Å; T306-K310 VanDerWaalsContact O-CB 3.24Å; T306-K310 WeakPolarHBondContact O-CB 3.46Å; T306-K310 VanDerWaalsContact O-CG 3.24Å; T306-K310 WeakPolarHBondContact O-CG 3.37Å; T306-K310 PolarHBondContact O-N 3.24Å; F307-K310 PolarHBondContact O-N 2.87Å; R308-K310 PolarHBondContact O-N 3.32Å; K310-R313 PolarHBondContact O-N 2.99Å; K310-A314 WeakPolarHBondContact O-CB 3.38Å; K310-A314 PolarHBondContact O-N 2.94Å
311	L	73.6	Confident	65.8	Low	35 Å²	35	86.2 Å²	86.2	18%	0.183	41%	0.406	C	S	.	.	H	α-helix	trans	-64.1	-46.3	176	-178	69.3	0	0	0	111.2	L48 M52 F301 F307 R308 R313 A314 T315	L48-L311 HydrophobicContact CD1-CD1 4.14Å; M52-L311 HydrophobicContact CE-CB 3.85Å; M52-L311 HydrophobicContact CE-CD1 4.33Å; M52-L311 HydrophobicContact CG-CD1 4.06Å; M52-L311 HydrophobicContact SD-CB 4.25Å; M52-L311 HydrophobicContact SD-CD1 3.64Å; F301-L311 HydrophobicContact CD1-CD2 4.21Å; F301-L311 HydrophobicContact CE1-CD2 3.74Å; F307-L311 WeakPolarHBondContact O-CB 3.33Å; F307-L311 PolarHBondContact O-N 2.95Å; R308-L311 PolarHBondContact O-N 3.19Å; L311-R313 VanDerWaalsContact C-N 3.28Å; L311-R313 PolarHBondContact O-N 3.06Å; L311-A314 PolarHBondContact O-N 2.89Å; L311-T315 HydrophobicContact CD1-CG2 4.24Å; L311-T315 HydrophobicContact CG-CG2 4.42Å; L311-T315 WeakPolarHBondContact O-CB 3.34Å; L311-T315 WeakPolarHBondContact O-CG2 3.36Å; L311-T315 PolarHBondContact O-N 3.03Å; L311-T315 PolarHBondContact O-OG1 3.46Å
312	S	72.7	Confident	65.2	Low	54 Å²	54	85.4 Å²	85.4	38%	0.378	41%	0.412	S	S	.	.	H	α-helix	trans	-59.5	-39.7	175	-178.9	0	0	0	0	111.7	R308 T315 K316	R308-S312 PolarHBondContact O-N 3.25Å; S312-T315 WeakPolarHBondContact CA-OG1 3.43Å; S312-T315 PolarHBondContact O-OG1 3.09Å; S312-T315 VanDerWaalsContact O-OG1 3.09Å; S312-K316 WeakPolarHBondContact O-CB 3.38Å; S312-K316 VanDerWaalsContact O-CG 3.22Å; S312-K316 WeakPolarHBondContact O-CG 3.47Å; S312-K316 PolarHBondContact O-N 3.06Å; S312-K316 VanDerWaalsContact O-N 3.09Å
313	R	76.1	Confident	64.9	Low	176 Å²	176	86 Å²	86	66%	0.664	42%	0.416	S	S	*	.	H	α-helix	trans	-68.7	-40.9	174.9	-75.6	179	168.6	-174.8	-4	112.9	R309 K310 L311 K317	R309-R313 WeakPolarHBondContact O-CG 3.44Å; R309-R313 PolarHBondContact O-N 3.28Å; R309-R313 VanDerWaalsContact O-N 3.14Å; K310-R313 PolarHBondContact O-N 2.99Å; L311-R313 VanDerWaalsContact C-N 3.28Å; L311-R313 PolarHBondContact O-N 3.06Å; R313-K317 WeakPolarHBondContact O-CB 3.5Å; R313-K317 PolarHBondContact O-N 3.42Å
314	A	73.9	Confident	65.1	Low	3 Å²	3	90.1 Å²	90.1	3%	0.025	44%	0.44	C	S	.	.	H	α-helix	trans	-65.5	-50	179.3	0	0	0	0	0	111.2	W51 M52 H56 K310 L311 K316 K317 T318	W51-A314 HydrophobicContact CH2-CB 4.17Å; M52-A314 HydrophobicContact SD-CB 4.47Å; H56-A314 WeakPolarHBondContact NE2-CB 3.04Å; K310-A314 WeakPolarHBondContact O-CB 3.38Å; K310-A314 PolarHBondContact O-N 2.94Å; L311-A314 PolarHBondContact O-N 2.89Å; A314-K316 PolarHBondContact O-N 2.84Å; A314-K317 PolarHBondContact O-N 3.43Å; A314-K317 VanDerWaalsContact O-N 3.11Å; A314-T318 PolarHBondContact O-N 3.09Å; A314-T318 PolarHBondContact O-OG1 3.26Å
315	T	75.5	Confident	65	Low	72 Å²	72	93 Å²	93	44%	0.442	45%	0.454	S	S	.	.	H	α-helix	trans	-60.5	-42.2	176.9	49.2	0	0	0	0	112.2	L311 S312 K317 T318 S319	L311-T315 HydrophobicContact CD1-CG2 4.24Å; L311-T315 HydrophobicContact CG-CG2 4.42Å; L311-T315 WeakPolarHBondContact O-CB 3.34Å; L311-T315 WeakPolarHBondContact O-CG2 3.36Å; L311-T315 PolarHBondContact O-N 3.03Å; L311-T315 PolarHBondContact O-OG1 3.46Å; S312-T315 WeakPolarHBondContact CA-OG1 3.43Å; S312-T315 PolarHBondContact O-OG1 3.09Å; S312-T315 VanDerWaalsContact O-OG1 3.09Å; T315-K317 PolarHBondContact O-N 3.15Å; T315-T318 PolarHBondContact O-N 2.88Å; T315-S319 WeakPolarHBondContact O-CB 3.09Å; T315-S319 PolarHBondContact O-N 3.38Å
316	K	73.7	Confident	65.1	Low	142 Å²	142	95.4 Å²	95.4	62%	0.617	47%	0.466	S	S	*	.	H	α-helix	trans	-63.1	-37.8	172.6	-75.7	179.6	179.6	-171.8	0	113.3	S312 A314 R320	S312-K316 WeakPolarHBondContact O-CB 3.38Å; S312-K316 VanDerWaalsContact O-CG 3.22Å; S312-K316 WeakPolarHBondContact O-CG 3.47Å; S312-K316 PolarHBondContact O-N 3.06Å; S312-K316 VanDerWaalsContact O-N 3.09Å; A314-K316 PolarHBondContact O-N 2.84Å; K316-R320 PolarHBondContact O-N 3.35Å
317	K	63.3	Low	65	Low	162 Å²	162	98.1 Å²	98.1	70%	0.704	47%	0.474	S	S	*	.	H	α-helix	trans	-70.6	-38	177.9	-166.5	174.9	-177.8	179.2	0	111.5	R313 A314 T315 K321	R313-K317 WeakPolarHBondContact O-CB 3.5Å; R313-K317 PolarHBondContact O-N 3.42Å; A314-K317 PolarHBondContact O-N 3.43Å; A314-K317 VanDerWaalsContact O-N 3.11Å; T315-K317 PolarHBondContact O-N 3.15Å; K317-K321 WeakPolarHBondContact O-CB 3.23Å; K317-K321 PolarHBondContact O-N 2.82Å
318	T	60.4	Low	64.8	Low	86 Å²	86	101 Å²	101	53%	0.528	50%	0.495	S	S	.	.	H	α-helix	trans	-68.4	-40.5	174.4	-50.5	0	0	0	0	111.5	A314 T315 K321 G322	A314-T318 PolarHBondContact O-N 3.09Å; A314-T318 PolarHBondContact O-OG1 3.26Å; T315-T318 PolarHBondContact O-N 2.88Å; T318-K321 PolarHBondContact O-N 3.28Å; T318-G322 PolarHBondContact O-N 2.93Å
319	S	62.4	Low	64.7	Low	70 Å²	70	100 Å²	100	49%	0.49	50%	0.495	S	S	.	.	H	α-helix	trans	-58.3	-53.9	173.3	-168.1	0	0	0	0	111.2	T315 K321 G322 D323	T315-S319 WeakPolarHBondContact O-CB 3.09Å; T315-S319 PolarHBondContact O-N 3.38Å; S319-K321 VanDerWaalsContact C-N 3.27Å; S319-K321 PolarHBondContact O-N 3.12Å; S319-G322 WeakPolarHBondContact O-CA 3.23Å; S319-G322 PolarHBondContact O-N 3.44Å; S319-D323 VanDerWaalsContact O-CG 3.25Å; S319-D323 PolarHBondContact O-N 2.66Å
320	R	58.3	Low	64.7	Low	196 Å²	196	96.5 Å²	96.5	74%	0.74	49%	0.493	S	S	*	.	H	α-helix	trans	-58.2	-37.2	177.1	-81.9	-176	168.7	-175.4	-4.7	113.1	K316 D323 T324	K316-R320 PolarHBondContact O-N 3.35Å; R320-D323 PolarHBondContact O-N 3.3Å; R320-T324 WeakPolarHBondContact O-CB 3.37Å; R320-T324 PolarHBondContact O-N 3.23Å; R320-T324 PolarHBondContact O-OG1 3.23Å
321	K	56.2	Low	64.4	Low	155 Å²	155	98 Å²	98	67%	0.674	50%	0.504	S	S	*	.	H	α-helix	trans	-70.8	-33.9	178	-152.8	-179.8	-175.4	-168.9	0	111.7	K317 T318 S319 V325	K317-K321 WeakPolarHBondContact O-CB 3.23Å; K317-K321 PolarHBondContact O-N 2.82Å; T318-K321 PolarHBondContact O-N 3.28Å; S319-K321 VanDerWaalsContact C-N 3.27Å; S319-K321 PolarHBondContact O-N 3.12Å; K321-V325 WeakPolarHBondContact O-CB 3.42Å; K321-V325 WeakPolarHBondContact O-CG2 3.43Å; K321-V325 PolarHBondContact O-N 3.25Å
322	G	54.6	Low	64.1	Low	33 Å²	33	102.1 Å²	102.1	34%	0.34	52%	0.523	S	S	.	.	H	α-helix	trans	-65.1	-45.6	170.5	0	0	0	0	0	112.2	T318 S319 T324 V325 L326	T318-G322 PolarHBondContact O-N 2.93Å; S319-G322 WeakPolarHBondContact O-CA 3.23Å; S319-G322 PolarHBondContact O-N 3.44Å; G322-T324 PolarHBondContact O-N 3.01Å; G322-V325 PolarHBondContact O-N 2.88Å; G322-L326 WeakPolarHBondContact O-CB 3.29Å; G322-L326 PolarHBondContact O-N 3.45Å
323	D	59	Low	64.2	Low	85 Å²	85	104.1 Å²	104.1	46%	0.455	53%	0.533	S	S	.	.	H	α-helix	trans	-63.4	-41.5	178	-58.8	-31.4	0	0	0	111.6	S319 R320 V325 L326 Q327	S319-D323 VanDerWaalsContact O-CG 3.25Å; S319-D323 PolarHBondContact O-N 2.66Å; R320-D323 PolarHBondContact O-N 3.3Å; D323-V325 PolarHBondContact O-N 3.41Å; D323-L326 PolarHBondContact O-N 3.18Å; D323-Q327 VanDerWaalsContact O-CB 3.26Å; D323-Q327 WeakPolarHBondContact O-CB 3.41Å; D323-Q327 PolarHBondContact O-N 3.39Å
324	T	57.8	Low	63.9	Low	94 Å²	94	98 Å²	98	58%	0.577	52%	0.52	S	S	*	.	H	α-helix	trans	-67.2	-35.4	178.7	-43.8	0	0	0	0	112.2	R320 G322 S328	R320-T324 WeakPolarHBondContact O-CB 3.37Å; R320-T324 PolarHBondContact O-N 3.23Å; R320-T324 PolarHBondContact O-OG1 3.23Å; G322-T324 PolarHBondContact O-N 3.01Å; T324-S328 PolarHBondContact O-N 2.99Å
325	V	59.3	Low	63.6	Low	80 Å²	80	103.9 Å²	103.9	49%	0.485	55%	0.55	S	S	.	.	H	α-helix	trans	-76	-35.9	177.7	170.9	0	0	0	0	111.7	K321 G322 D323 Q327 K329	K321-V325 WeakPolarHBondContact O-CB 3.42Å; K321-V325 WeakPolarHBondContact O-CG2 3.43Å; K321-V325 PolarHBondContact O-N 3.25Å; G322-V325 PolarHBondContact O-N 2.88Å; D323-V325 PolarHBondContact O-N 3.41Å; V325-Q327 VanDerWaalsContact C-N 3.35Å; V325-K329 PolarHBondContact O-N 3.38Å; V325-K329 VanDerWaalsContact O-N 3.15Å
326	L	59.3	Low	63.5	Low	124 Å²	124	105.4 Å²	105.4	65%	0.649	56%	0.555	S	S	*	*	H	α-helix	trans	-65.6	-40	171.7	-83.9	157.6	0	0	0	111.3	G322 D323 K329 S330	G322-L326 WeakPolarHBondContact O-CB 3.29Å; G322-L326 PolarHBondContact O-N 3.45Å; D323-L326 PolarHBondContact O-N 3.18Å; L326-K329 PolarHBondContact O-N 3.41Å; L326-S330 WeakPolarHBondContact O-CB 3.13Å; L326-S330 PolarHBondContact O-N 3.43Å
327	Q	59.7	Low	63.4	Low	125 Å²	125	101.8 Å²	101.8	58%	0.584	55%	0.548	S	S	*	.	H	α-helix	trans	-68.8	-43.6	178	-162.7	152.2	5.6	0	0	111.9	D323 V325 K329 S330 D331	D323-Q327 VanDerWaalsContact O-CB 3.26Å; D323-Q327 WeakPolarHBondContact O-CB 3.41Å; D323-Q327 PolarHBondContact O-N 3.39Å; V325-Q327 VanDerWaalsContact C-N 3.35Å; Q327-K329 VanDerWaalsContact C-N 3.32Å; Q327-K329 PolarHBondContact O-N 2.86Å; Q327-S330 WeakPolarHBondContact O-CB 3.34Å; Q327-S330 PolarHBondContact O-N 3.39Å; Q327-S330 VanDerWaalsContact O-N 3.13Å; Q327-D331 VanDerWaalsContact O-CG 3.22Å; Q327-D331 PolarHBondContact O-N 2.86Å
328	S	58.3	Low	63.6	Low	64 Å²	64	99.7 Å²	99.7	45%	0.448	54%	0.544	S	S	.	.	H	α-helix	trans	-63.4	-36.6	175.9	97.5	0	0	0	0	112.8	T324 D331 E332	T324-S328 PolarHBondContact O-N 2.99Å; S328-D331 PolarHBondContact O-N 2.72Å; S328-E332 VanDerWaalsContact O-CB 3.32Å; S328-E332 WeakPolarHBondContact O-CB 3.41Å; S328-E332 PolarHBondContact O-N 3.08Å
329	K	65.6	Low	64.1	Low	134 Å²	134	98.4 Å²	98.4	58%	0.583	54%	0.542	S	S	*	.	H	α-helix	trans	-67.2	-38	173.8	-82.2	-172.5	171.6	-171	0	112.4	V325 L326 Q327 T333	V325-K329 PolarHBondContact O-N 3.38Å; V325-K329 VanDerWaalsContact O-N 3.15Å; L326-K329 PolarHBondContact O-N 3.41Å; Q327-K329 VanDerWaalsContact C-N 3.32Å; Q327-K329 PolarHBondContact O-N 2.86Å; K329-T333 WeakPolarHBondContact O-CB 3.46Å; K329-T333 PolarHBondContact O-N 3.25Å; K329-T333 PolarHBondContact O-OG1 3.44Å
330	S	66.3	Low	64.5	Low	76 Å²	76	101.1 Å²	101.1	53%	0.531	55%	0.547	S	S	.	.	H	α-helix	trans	-64.6	-43	175.6	-169.1	0	0	0	0	111.3	L326 Q327 T333 A334	L326-S330 WeakPolarHBondContact O-CB 3.13Å; L326-S330 PolarHBondContact O-N 3.43Å; Q327-S330 WeakPolarHBondContact O-CB 3.34Å; Q327-S330 PolarHBondContact O-N 3.39Å; Q327-S330 VanDerWaalsContact O-N 3.13Å; S330-T333 PolarHBondContact O-N 3.46Å; S330-A334 WeakPolarHBondContact O-CB 3.38Å; S330-A334 PolarHBondContact O-N 2.87Å
331	D	65.8	Low	64.9	Low	92 Å²	92	101 Å²	101	49%	0.492	55%	0.547	S	S	.	.	H	α-helix	trans	-67.9	-39.6	179.7	-64.5	-23.1	0	0	0	111.7	Q327 S328 A334 L335	Q327-D331 VanDerWaalsContact O-CG 3.22Å; Q327-D331 PolarHBondContact O-N 2.86Å; S328-D331 PolarHBondContact O-N 2.72Å; D331-A334 PolarHBondContact O-N 3.28Å; D331-L335 PolarHBondContact O-N 3.41Å
332	E	68.3	Low	65.6	Low	122 Å²	122	97.9 Å²	97.9	57%	0.57	54%	0.541	S	S	*	.	H	α-helix	trans	-66.7	-37.9	175.6	-166.5	175.2	-171.4	0	0	112	S328 L335 N336	S328-E332 VanDerWaalsContact O-CB 3.32Å; S328-E332 WeakPolarHBondContact O-CB 3.41Å; S328-E332 PolarHBondContact O-N 3.08Å; E332-L335 PolarHBondContact O-N 3.38Å; E332-N336 VanDerWaalsContact O-CG 3.27Å; E332-N336 PolarHBondContact O-N 2.05Å; E332-N336 VanDerWaalsContact O-N 3.12Å; E332-N336 PolarHBondContact O-ND2 3.25Å
333	T	73.5	Confident	66.2	Low	96 Å²	96	101.5 Å²	101.5	59%	0.589	55%	0.55	S	S	*	.	H	α-helix	trans	-68.5	-37.5	175.5	-49.2	0	0	0	0	111.6	K329 S330 S337	K329-T333 WeakPolarHBondContact O-CB 3.46Å; K329-T333 PolarHBondContact O-N 3.25Å; K329-T333 PolarHBondContact O-OG1 3.44Å; S330-T333 PolarHBondContact O-N 3.46Å; T333-S337 PolarHBondContact O-N 3.25Å; T333-S337 PolarHBondContact O-OG 3.18Å
334	A	70.9	Confident	66.5	Low	47 Å²	47	101.3 Å²	101.3	39%	0.388	55%	0.549	S	S	.	.	H	α-helix	trans	-69.9	-35	175.5	0	0	0	0	0	112.7	S330 D331 S337 L338	S330-A334 WeakPolarHBondContact O-CB 3.38Å; S330-A334 PolarHBondContact O-N 2.87Å; D331-A334 PolarHBondContact O-N 3.28Å; A334-S337 PolarHBondContact O-OG 2.98Å; A334-L338 PolarHBondContact O-N 3.21Å
335	L	67.4	Low	66.8	Low	127 Å²	127	98.6 Å²	98.6	67%	0.665	54%	0.539	S	S	*	.	H	α-helix	trans	-66.9	-41.3	175.5	-125	99.2	0	0	0	111.8	D331 E332 L338 A339	D331-L335 PolarHBondContact O-N 3.41Å; E332-L335 PolarHBondContact O-N 3.38Å; L335-L338 PolarHBondContact O-N 3.35Å; L335-A339 PolarHBondContact O-N 3.45Å
336	N	73.4	Confident	66.7	Low	104 Å²	104	100.8 Å²	100.8	56%	0.556	55%	0.548	S	S	*	.	H	α-helix	trans	-67.4	-38.7	-180	-71.1	-21	0	0	0	112.1	E332 L338 A339 E340	E332-N336 VanDerWaalsContact O-CG 3.27Å; E332-N336 PolarHBondContact O-N 2.05Å; E332-N336 VanDerWaalsContact O-N 3.12Å; E332-N336 PolarHBondContact O-ND2 3.25Å; N336-L338 VanDerWaalsContact C-N 3.35Å; N336-A339 PolarHBondContact O-N 3.47Å; N336-E340 WeakPolarHBondContact O-CB 3.43Å; N336-E340 PolarHBondContact O-N 3.46Å; N336-E340 VanDerWaalsContact O-N 3.08Å
337	S	72	Confident	66.6	Low	65 Å²	65	103.5 Å²	103.5	46%	0.455	55%	0.55	S	S	.	.	H	α-helix	trans	-68.9	-32.9	175.8	64.7	0	0	0	0	112.8	T333 A334 Y341	T333-S337 PolarHBondContact O-N 3.25Å; T333-S337 PolarHBondContact O-OG 3.18Å; A334-S337 PolarHBondContact O-OG 2.98Å; S337-Y341 PolarHBondContact O-N 3.03Å
338	L	67.8	Low	66.4	Low	119 Å²	119	107.9 Å²	107.9	62%	0.623	56%	0.561	S	S	*	*	H	α-helix	trans	-68.5	-41.6	174.2	-121.9	129.9	0	0	0	111.9	A334 L335 N336 E340 Y341 V342	A334-L338 PolarHBondContact O-N 3.21Å; L335-L338 PolarHBondContact O-N 3.35Å; N336-L338 VanDerWaalsContact C-N 3.35Å; L338-E340 VanDerWaalsContact C-N 3.33Å; L338-E340 PolarHBondContact O-N 3.36Å; L338-Y341 PolarHBondContact O-N 3.02Å; L338-V342 WeakPolarHBondContact O-CG2 3.42Å; L338-V342 PolarHBondContact O-N 3.34Å
339	A	71.2	Confident	65.9	Low	59 Å²	59	114.3 Å²	114.3	49%	0.488	59%	0.59	S	S	.	*	H	α-helix	trans	-61.2	-42.5	174.9	0	0	0	0	0	111.6	L335 N336 Y341 V342 E343	L335-A339 PolarHBondContact O-N 3.45Å; N336-A339 PolarHBondContact O-N 3.47Å; A339-Y341 VanDerWaalsContact C-N 3.32Å; A339-Y341 PolarHBondContact O-N 2.84Å; A339-V342 PolarHBondContact O-N 2.88Å; A339-E343 WeakPolarHBondContact O-CB 3.43Å; A339-E343 PolarHBondContact O-N 3.11Å
340	E	69.1	Low	65.9	Low	127 Å²	127	113.4 Å²	113.4	59%	0.593	59%	0.591	S	S	*	*	H	α-helix	trans	-66.6	-32.2	177.4	-158.8	173.7	-159.3	0	0	112.3	N336 L338 N344	N336-E340 WeakPolarHBondContact O-CB 3.43Å; N336-E340 PolarHBondContact O-N 3.46Å; N336-E340 VanDerWaalsContact O-N 3.08Å; L338-E340 VanDerWaalsContact C-N 3.33Å; L338-E340 PolarHBondContact O-N 3.36Å; E340-N344 VanDerWaalsContact O-CB 3.32Å; E340-N344 WeakPolarHBondContact O-CB 3.42Å; E340-N344 VanDerWaalsContact O-CG 3.31Å; E340-N344 PolarHBondContact O-N 2.88Å; E340-N344 VanDerWaalsContact O-N 3.08Å; E340-N344 PolarHBondContact O-ND2 3.38Å
341	Y	67.1	Low	65.9	Low	192 Å²	192	115.3 Å²	115.3	75%	0.753	59%	0.594	S	S	*	*	H	α-helix	trans	-70.8	-41.4	174.4	-144.7	-88.2	0	0	0	112.4	S337 L338 A339 N344 G345	S337-Y341 PolarHBondContact O-N 3.03Å; L338-Y341 PolarHBondContact O-N 3.02Å; A339-Y341 VanDerWaalsContact C-N 3.32Å; A339-Y341 PolarHBondContact O-N 2.84Å; Y341-N344 PolarHBondContact O-N 3.37Å; Y341-G345 PolarHBondContact O-N 2.96Å
342	V	70.4	Confident	65.9	Low	90 Å²	90	116.6 Å²	116.6	55%	0.545	60%	0.599	S	S	.	*	H	α-helix	trans	-66.6	-41.2	177	172.1	0	0	0	0	110.9	L338 A339 G345 N346	L338-V342 WeakPolarHBondContact O-CG2 3.42Å; L338-V342 PolarHBondContact O-N 3.34Å; A339-V342 PolarHBondContact O-N 2.88Å; V342-G345 PolarHBondContact O-N 2.97Å; V342-N346 PolarHBondContact O-N 3.18Å
343	E	67.1	Low	65.8	Low	110 Å²	110	116.3 Å²	116.3	51%	0.514	60%	0.601	S	S	.	*	H	α-helix	trans	-66.9	-38.5	178	-158.2	-177	158.5	0	0	112	A339 R347	A339-E343 WeakPolarHBondContact O-CB 3.43Å; A339-E343 PolarHBondContact O-N 3.11Å; E343-R347 PolarHBondContact O-N 3.05Å; E343-R347 IonicContact OE1-CZ 3.78Å; E343-R347 IonicContact OE1-NH2 2.81Å; E343-R347 PolarHBondContact OE1-NH2 3.48Å
344	N	65.7	Low	65.3	Low	81 Å²	81	117.6 Å²	117.6	43%	0.433	60%	0.602	S	S	.	*	H	α-helix	trans	-73.3	-30.4	175.3	-77.2	-40.6	0	0	0	113.4	E340 Y341	E340-N344 VanDerWaalsContact O-CB 3.32Å; E340-N344 WeakPolarHBondContact O-CB 3.42Å; E340-N344 VanDerWaalsContact O-CG 3.31Å; E340-N344 PolarHBondContact O-N 2.88Å; E340-N344 VanDerWaalsContact O-N 3.08Å; E340-N344 PolarHBondContact O-ND2 3.38Å; Y341-N344 PolarHBondContact O-N 3.37Å
345	G	65.2	Low	64.9	Low	36 Å²	36	122.3 Å²	122.3	37%	0.371	62%	0.616	S	S	.	*	H	α-helix	trans	-67.1	-39.8	173	0	0	0	0	0	112.6	Y341 V342 R347 R348	Y341-G345 PolarHBondContact O-N 2.96Å; V342-G345 PolarHBondContact O-N 2.97Å; G345-R347 VanDerWaalsContact C-N 3.29Å; G345-R347 PolarHBondContact O-N 3.14Å; G345-R348 PolarHBondContact O-N 2.97Å
346	N	56.4	Low	64.7	Low	127 Å²	127	121.9 Å²	121.9	68%	0.679	61%	0.613	S	S	*	*	H	α-helix	trans	-73.4	-14.3	177.4	-98.1	-0.4	0	0	0	114.6	V342	V342-N346 PolarHBondContact O-N 3.18Å
347	R	57.1	Low	64.1	Low	180 Å²	180	123.3 Å²	123.3	68%	0.679	62%	0.617	S	S	*	*	T	Hydrogen-bonded Turn	trans	-90.2	-4.5	173.7	-71.6	-175.9	-165.5	-171.9	8	113.8	E343 G345	E343-R347 PolarHBondContact O-N 3.05Å; E343-R347 IonicContact OE1-CZ 3.78Å; E343-R347 IonicContact OE1-NH2 2.81Å; E343-R347 PolarHBondContact OE1-NH2 3.48Å; G345-R347 VanDerWaalsContact C-N 3.29Å; G345-R347 PolarHBondContact O-N 3.14Å
348	R	55.3	Low	63.4	Low	218 Å²	218	128.2 Å²	128.2	82%	0.823	63%	0.631	S	S	*	*			trans	-110.4	-1.3	-176.8	-72.8	-175.1	-176.5	-179.1	2.7	114.5	G345	G345-R348 PolarHBondContact O-N 2.97Å
349	N	48.5	Very low	63	Low	199 Å²	199	129 Å²	129	100%	1.064	63%	0.631	S	S	*	*			trans	-107.9	0	165.7	-69.2	-19.8	0	0	0	108.6

Retrieved 349 of 349 residues in 569.1 ms (Link to these results)

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