A0A096MNK0_PAPAN Loading...

Synaptic vesicle 2-related protein

AlphaFold DB (A0A2K6QZ53), UniProt , Accession A0A096MNK0, Species PAPAN (Papio anubis, Olive baboon), Gene SVOP, Length 548 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	37	Very low	30.5	Very low	239 Å²	239	171 Å²	171	100%	1.177	81%	0.807	S	S	*	*				0	41	0	-156.2	-167.8	-32	0	0	109.6
2	E	26.7	Very low	30.3	Very low	177 Å²	177	164.8 Å²	164.8	83%	0.827	79%	0.792	S	S	*	*			trans	-141.7	-3.2	-174.3	-95.6	176.1	152.8	0	0	112.8
3	E	25.4	Very low	30.6	Very low	187 Å²	187	159 Å²	159	87%	0.874	77%	0.773	S	S	*	*	S	Bend	trans	-93.3	-11.5	-179.6	-74.2	179.2	146.6	0	0	114	L5	E3-L5 PolarHBondContact O-N 3Å
4	D	28.4	Very low	30.9	Very low	159 Å²	159	153.2 Å²	153.2	85%	0.85	75%	0.751	S	S	*	*	G	3₁₀ helix	trans	-87	-0.5	178.6	-72.9	-30.8	0	0	0	114	F6	D4-F6 VanDerWaalsContact C-N 3.31Å
5	L	32.5	Very low	30.8	Very low	134 Å²	134	154.1 Å²	154.1	70%	0.702	75%	0.749	S	S	*	*	G	3₁₀ helix	trans	-79.3	-13.1	177.5	-124.8	93.8	0	0	0	113.3	E3	E3-L5 PolarHBondContact O-N 3Å
6	F	27.1	Very low	31	Very low	193 Å²	193	153 Å²	153	85%	0.846	74%	0.74	S	S	*	*	G	3₁₀ helix	trans	-97	1	-168.4	-115.3	-87.4	0	0	0	116	D4 L8	D4-F6 VanDerWaalsContact C-N 3.31Å; F6-L8 VanDerWaalsContact C-N 3.35Å
7	Q	27.3	Very low	30.9	Very low	190 Å²	190	158.3 Å²	158.3	89%	0.888	75%	0.751	S	S	*	*	G	3₁₀ helix	trans	-94.5	23.3	172	-73	-154.8	-9	0	0	114.3	R9	Q7-R9 VanDerWaalsContact C-N 3.27Å; Q7-R9 PolarHBondContact O-N 3.27Å
8	L	31.6	Very low	30.8	Very low	115 Å²	115	161.9 Å²	161.9	60%	0.602	76%	0.756	S	S	*	*			trans	-85.9	27.6	176.8	-82.7	166	0	0	0	114.8	F6	F6-L8 VanDerWaalsContact C-N 3.35Å
9	R	32.2	Very low	30.9	Very low	229 Å²	229	160.2 Å²	160.2	86%	0.864	76%	0.757	S	S	*	*			trans	-107.5	123.5	173.2	-102.7	-175.5	-176.6	-165.8	1.4	111.3	Q7	Q7-R9 VanDerWaalsContact C-N 3.27Å; Q7-R9 PolarHBondContact O-N 3.27Å
10	Q	31.6	Very low	30.8	Very low	183 Å²	183	155.8 Å²	155.8	86%	0.855	76%	0.757	S	S	*	*			trans	90.5	65.6	163.9	-53.2	-179.8	-3.1	0	0	116.7
11	L	35.7	Very low	30.5	Very low	75 Å²	75	157.4 Å²	157.4	39%	0.393	76%	0.763	S	S	.	*			trans	-110.9	130.2	147.6	-71.5	170.5	0	0	0	108.5	V13 T283	L11-V13 PolarHBondContact O-N 3.48Å; L11-T283 HydrophobicContact CD1-CG2 4.2Å
12	P	28.3	Very low	30.1	Very low	97 Å²	97	150.7 Å²	150.7	63%	0.63	74%	0.74	S	S	*	*			trans	-75.1	104.8	-175.3	28.2	-32.8	0	0	0	111.1	P288	P12-P288 WeakPolarHBondContact O-CB 3.36Å; P12-P288 WeakPolarHBondContact O-CG 3.24Å
13	V	34	Very low	30.3	Very low	89 Å²	89	147.4 Å²	147.4	54%	0.539	74%	0.743	S	S	.	*			trans	-72.3	139.7	-171.2	-171.3	0	0	0	0	113.1	L11 L291	L11-V13 PolarHBondContact O-N 3.48Å; V13-L291 HydrophobicContact CG1-CD1 3.81Å; V13-L291 HydrophobicContact CG1-CD2 4.14Å; V13-L291 HydrophobicContact CG1-CG 3.76Å
14	V	35	Very low	30.4	Very low	78 Å²	78	149.2 Å²	149.2	47%	0.473	74%	0.742	S	S	.	*			trans	-113.6	130.1	174.9	177.4	0	0	0	0	109.8	F16 P288	V14-F16 HydrophobicContact CG1-CE2 4.4Å; V14-P288 HydrophobicContact CB-CG 4.39Å; V14-P288 HydrophobicContact CG2-CG 3.92Å
15	K	29.9	Very low	30.3	Very low	166 Å²	166	146.8 Å²	146.8	72%	0.722	74%	0.737	S	S	*	*	P	Polyproline II helix	trans	-95.1	126.3	177	-164.4	174.5	-175.4	176.8	0	109.4
16	F	33.3	Very low	30	Very low	137 Å²	137	150 Å²	150	60%	0.601	75%	0.749	S	S	*	*	P	Polyproline II helix	trans	-91.6	149.5	172.4	-86.6	-87.5	0	0	0	111.5	V14 A76	V14-F16 HydrophobicContact CG1-CE2 4.4Å; F16-A76 HydrophobicContact CE2-CB 3.65Å; F16-A76 HydrophobicContact CZ-CB 4.16Å
17	R	29.3	Very low	30	Very low	243 Å²	243	147.1 Å²	147.1	92%	0.917	74%	0.742	S	S	*	*	P	Polyproline II helix	trans	-85.4	139.4	178.1	-160.2	176.7	-171.4	172	1.2	109.4	T19	R17-T19 PolarHBondContact O-N 3.31Å
18	R	29.6	Very low	29.9	Very low	224 Å²	224	146.3 Å²	146.3	85%	0.845	74%	0.744	S	S	*	*			trans	-39.2	119	-176.9	-78.9	178.5	172.4	171.1	-3.3	114.2
19	T	32.4	Very low	29.7	Very low	128 Å²	128	147.4 Å²	147.4	79%	0.785	76%	0.756	S	S	*	*			trans	-85.8	102.9	160.2	41.1	0	0	0	0	109.1	R17	R17-T19 PolarHBondContact O-N 3.31Å
20	G	28.9	Very low	29.4	Very low	73 Å²	73	140.5 Å²	140.5	75%	0.753	75%	0.748	S	S	*	*			trans	-168.9	-9.8	179.5	0	0	0	0	0	115.3
21	E	25.1	Very low	29	Very low	190 Å²	190	137.7 Å²	137.7	89%	0.888	75%	0.748	S	S	*	*	S	Bend	trans	-111.8	115.7	170.4	-74.2	179.3	154.6	0	0	109.1
22	S	27	Very low	28.5	Very low	98 Å²	98	137.8 Å²	137.8	69%	0.685	77%	0.767	S	S	*	*			trans	-50.9	140.3	166.5	63.5	0	0	0	0	109.7	R24	S22-R24 PolarHBondContact O-N 3.37Å
23	A	31.6	Very low	28.4	Very low	108 Å²	108	142.1 Å²	142.1	89%	0.893	78%	0.779	S	S	*	*			trans	-37.1	111.5	163.6	0	0	0	0	0	111.5
24	R	26.6	Very low	27.9	Very low	224 Å²	224	146.5 Å²	146.5	85%	0.845	79%	0.793	S	S	*	*			trans	-127.7	115.4	162	-93.5	-174.3	170.8	172.2	-2.5	108	S22	S22-R24 PolarHBondContact O-N 3.37Å
25	S	26.7	Very low	27.4	Very low	108 Å²	108	151 Å²	151	76%	0.755	81%	0.809	S	S	*	*			trans	51.1	90.9	160.5	62.9	0	0	0	0	117.8	D27	S25-D27 VanDerWaalsContact C-N 3.26Å; S25-D27 PolarHBondContact O-N 3.5Å
26	E	26.9	Very low	27.1	Very low	201 Å²	201	149 Å²	149	94%	0.939	81%	0.81	S	S	*	*			trans	-79.8	83.9	137.7	-74.1	-178.3	146.1	0	0	107.3
27	D	27.2	Very low	26.6	Very low	134 Å²	134	149.9 Å²	149.9	72%	0.717	82%	0.816	S	S	*	*			trans	-156.9	84	161.9	-111.1	-13.5	0	0	0	106.4	S25	S25-D27 VanDerWaalsContact C-N 3.26Å; S25-D27 PolarHBondContact O-N 3.5Å
28	D	25.4	Very low	26.4	Very low	172 Å²	172	146 Å²	146	92%	0.92	81%	0.812	S	S	*	*			trans	-162	67.3	156.8	-96.7	-21.5	0	0	0	108
29	T	26.8	Very low	26.1	Very low	139 Å²	139	143.6 Å²	143.6	85%	0.853	81%	0.81	S	S	*	*			trans	-93.8	95.1	158.4	48.3	0	0	0	0	108.6
30	A	25.2	Very low	26.1	Very low	84 Å²	84	140.9 Å²	140.9	69%	0.694	81%	0.808	S	S	*	*			trans	-164.7	122.6	150.8	0	0	0	0	0	112.5
31	S	24.7	Very low	25.9	Very low	124 Å²	124	143.9 Å²	143.9	87%	0.867	81%	0.811	S	S	*	*			trans	64.2	128.4	143.3	63.4	0	0	0	0	120.5
32	G	23.4	Very low	25.8	Very low	76 Å²	76	146.7 Å²	146.7	78%	0.784	81%	0.814	S	S	*	*			trans	137.5	97.7	149.6	0	0	0	0	0	113.3	H34	G32-H34 PolarHBondContact O-N 3.46Å
33	E	27.6	Very low	25.9	Very low	188 Å²	188	150.8 Å²	150.8	88%	0.879	82%	0.824	S	S	*	*			trans	-47.5	126.9	159.2	-66.4	168.9	143.3	0	0	110.3
34	H	24.1	Very low	25.6	Very low	182 Å²	182	148.3 Å²	148.3	84%	0.843	81%	0.809	S	S	*	*			trans	-149.9	99.1	143.3	-100.5	-51.4	0	0	0	109.3	G32 V36	G32-H34 PolarHBondContact O-N 3.46Å; H34-V36 PolarHBondContact O-N 3.4Å
35	E	24	Very low	25.7	Very low	173 Å²	173	146.5 Å²	146.5	81%	0.808	82%	0.815	S	S	*	*			trans	-50.2	121.8	150.5	-79.2	178.3	130.6	0	0	109
36	V	24	Very low	25.6	Very low	123 Å²	123	149.6 Å²	149.6	75%	0.745	82%	0.818	S	S	*	*			trans	-123.4	96.4	146.4	-178.6	0	0	0	0	106.2	H34 I38	H34-V36 PolarHBondContact O-N 3.4Å; V36-I38 PolarHBondContact O-N 2.86Å
37	Q	21.9	Very low	25.5	Very low	156 Å²	156	144.9 Å²	144.9	73%	0.729	81%	0.813	S	S	*	*			trans	-51.4	119.6	161.4	-103.9	173.5	-15	0	0	109.2
38	I	26.1	Very low	25.7	Very low	161 Å²	161	144.5 Å²	144.5	83%	0.826	82%	0.816	S	S	*	*			trans	-113.8	106.6	149.6	-61.6	-179.6	0	0	0	105.5	V36	V36-I38 PolarHBondContact O-N 2.86Å
39	E	23.2	Very low	25.9	Very low	173 Å²	173	145.2 Å²	145.2	81%	0.808	81%	0.813	S	S	*	*			trans	-61.2	134.7	177.1	-76.7	179.9	130.7	0	0	111.6
40	G	31.3	Very low	26.3	Very low	71 Å²	71	145.2 Å²	145.2	73%	0.732	81%	0.807	S	S	*	*			trans	84.4	66.2	136.2	0	0	0	0	0	118.1
41	V	24.6	Very low	26.9	Very low	137 Å²	137	148.2 Å²	148.2	83%	0.83	81%	0.812	S	S	*	*			trans	-140.8	116.2	142.5	-175.8	0	0	0	0	109.9	M43	V41-M43 PolarHBondContact O-N 2.94Å
42	R	24.4	Very low	27.4	Very low	249 Å²	249	150.5 Å²	150.5	94%	0.94	81%	0.814	S	S	*	*			trans	-70.3	103	171.4	-158.3	-177.2	-149.3	-176.9	5.5	107.3	G44	R42-G44 VanDerWaalsContact C-N 3.27Å; R42-G44 PolarHBondContact O-N 3.24Å
43	M	27.7	Very low	28.6	Very low	183 Å²	183	150.8 Å²	150.8	90%	0.901	82%	0.817	S	S	*	*			trans	-73.1	84.8	172.3	-76.8	-107.7	-63.6	0	0	109.6	V41	V41-M43 PolarHBondContact O-N 2.94Å
44	G	25	Very low	29	Very low	56 Å²	56	144.7 Å²	144.7	58%	0.577	80%	0.799	S	S	*	*			trans	-70.1	133	150.9	0	0	0	0	0	108.1	R42 E46	R42-G44 VanDerWaalsContact C-N 3.27Å; R42-G44 PolarHBondContact O-N 3.24Å; G44-E46 VanDerWaalsContact C-N 3.32Å; G44-E46 PolarHBondContact O-N 2.84Å
45	L	29.8	Very low	29.7	Very low	186 Å²	186	140.7 Å²	140.7	97%	0.974	80%	0.797	S	S	*	*			trans	-63.6	95	164.4	-91	137.4	0	0	0	108
46	E	23.3	Very low	30.3	Very low	174 Å²	174	136.8 Å²	136.8	81%	0.813	79%	0.785	S	S	*	*			trans	-100	120.4	161	-83.7	-176.1	163.5	0	0	108.7	G44 V48	G44-E46 VanDerWaalsContact C-N 3.32Å; G44-E46 PolarHBondContact O-N 2.84Å; E46-V48 PolarHBondContact O-N 3.38Å
47	A	25.1	Very low	30.7	Very low	101 Å²	101	134.7 Å²	134.7	84%	0.835	77%	0.774	S	S	*	*			trans	-67.1	113	165.8	0	0	0	0	0	107.4	E49	A47-E49 PolarHBondContact O-N 3.39Å
48	V	31.3	Very low	31.5	Very low	127 Å²	127	136.7 Å²	136.7	77%	0.77	78%	0.78	S	S	*	*			trans	-80.5	110.1	170.1	-179.4	0	0	0	0	107	E46 L50	E46-V48 PolarHBondContact O-N 3.38Å; V48-L50 PolarHBondContact O-N 3.27Å
49	E	30.3	Very low	32.1	Very low	186 Å²	186	137.7 Å²	137.7	87%	0.869	78%	0.781	S	S	*	*	P	Polyproline II helix	trans	-66.3	121.8	165.3	-72.7	-172.7	153.5	0	0	108.2	A47	A47-E49 PolarHBondContact O-N 3.39Å
50	L	34.7	Very low	32.7	Very low	139 Å²	139	137.3 Å²	137.3	73%	0.728	78%	0.777	S	S	*	*	P	Polyproline II helix	trans	-76.7	129.5	171.2	-82.6	155.5	0	0	0	108.3	V48 A54	V48-L50 PolarHBondContact O-N 3.27Å; L50-A54 HydrophobicContact CD2-CB 4.29Å
51	D	38.9	Very low	32.6	Very low	147 Å²	147	136.4 Å²	136.4	79%	0.786	76%	0.763	S	S	*	*	P	Polyproline II helix	trans	-63.1	141.3	175.5	-149	10.9	0	0	0	110.5	G53 A54	D51-G53 PolarHBondContact O-N 3.48Å; D51-A54 PolarHBondContact O-N 2.94Å
52	D	34.7	Very low	33.2	Very low	173 Å²	173	135.5 Å²	135.5	93%	0.925	75%	0.754	S	S	*	*	T	Hydrogen-bonded Turn	trans	-58.6	108.6	-172.5	-88.8	-31.3	0	0	0	111
53	G	49.2	Very low	34.2	Very low	81 Å²	81	129.1 Å²	129.1	84%	0.835	74%	0.744	S	S	*	*	T	Hydrogen-bonded Turn	trans	110.6	4.6	174.8	0	0	0	0	0	116.6	D51 A55	D51-G53 PolarHBondContact O-N 3.48Å; G53-A55 PolarHBondContact O-N 3.02Å
54	A	35.9	Very low	35.3	Very low	61 Å²	61	124 Å²	124	50%	0.504	72%	0.723	S	S	.	*	P	Polyproline II helix	trans	-69.9	128.5	174.1	0	0	0	0	0	112.3	L50 D51 V56	L50-A54 HydrophobicContact CD2-CB 4.29Å; D51-A54 PolarHBondContact O-N 2.94Å; A54-V56 PolarHBondContact O-N 3.4Å
55	A	38.9	Very low	36.7	Very low	98 Å²	98	127.2 Å²	127.2	81%	0.81	73%	0.728	S	S	*	*	P	Polyproline II helix	trans	-67.3	121.7	177.9	0	0	0	0	0	111	G53	G53-A55 PolarHBondContact O-N 3.02Å
56	V	36.2	Very low	38.5	Very low	90 Å²	90	121.2 Å²	121.2	55%	0.545	70%	0.697	S	S	.	*	P	Polyproline II helix	trans	-58.8	127	175.8	-176.9	0	0	0	0	109.2	A54 K58 F60 A61	A54-V56 PolarHBondContact O-N 3.4Å; V56-K58 PolarHBondContact O-N 2.88Å; V56-F60 HydrophobicContact CG1-CB 3.96Å; V56-A61 HydrophobicContact CG1-CB 4.34Å
57	P	32.8	Very low	41.2	Very low	80 Å²	80	116 Å²	116	52%	0.519	68%	0.677	S	S	.	*	P	Polyproline II helix	trans	-56.3	134.7	176.3	-19.9	28.9	0	0	0	110.2	E59 F60 A61	P57-E59 PolarHBondContact O-N 3.11Å; P57-F60 HydrophobicContact CB-CD2 4.18Å; P57-F60 HydrophobicContact CG-CD2 4.32Å; P57-F60 PolarHBondContact O-N 3.47Å; P57-A61 PolarHBondContact O-N 3.18Å
58	K	38.2	Very low	44	Very low	198 Å²	198	112 Å²	112	86%	0.861	64%	0.641	S	S	*	*	T	Hydrogen-bonded Turn	trans	-55.2	-21.2	-174.3	-79.6	-178.7	175.1	177.3	0	114.5	V56 F60	V56-K58 PolarHBondContact O-N 2.88Å; K58-F60 VanDerWaalsContact C-N 3.35Å
59	E	37.9	Very low	46.6	Very low	181 Å²	181	108.9 Å²	108.9	85%	0.846	62%	0.618	S	S	*	*	T	Hydrogen-bonded Turn	trans	-73.8	-22.3	175.2	-72.3	175.6	161.4	0	0	113.7	P57	P57-E59 PolarHBondContact O-N 3.11Å
60	F	35.7	Very low	49.1	Very low	165 Å²	165	100.5 Å²	100.5	72%	0.724	58%	0.58	S	S	*	*	T	Hydrogen-bonded Turn	trans	-99.4	-7.4	174.7	-67.4	-81.5	0	0	0	113.2	V56 P57 K58 N62	V56-F60 HydrophobicContact CG1-CB 3.96Å; P57-F60 HydrophobicContact CB-CD2 4.18Å; P57-F60 HydrophobicContact CG-CD2 4.32Å; P57-F60 PolarHBondContact O-N 3.47Å; K58-F60 VanDerWaalsContact C-N 3.35Å; F60-N62 PolarHBondContact O-N 3.46Å
61	A	29.9	Very low	51.4	Low	53 Å²	53	97.4 Å²	97.4	44%	0.438	56%	0.562	S	S	.	*			trans	-91.8	19.1	-174.8	0	0	0	0	0	114.4	V56 P57 P63	V56-A61 HydrophobicContact CG1-CB 4.34Å; P57-A61 PolarHBondContact O-N 3.18Å; A61-P63 WeakPolarHBondContact O-CD 3.4Å
62	N	37.1	Very low	53.6	Low	117 Å²	117	94.1 Å²	94.1	63%	0.626	54%	0.544	S	S	*	.			trans	-119.8	84.1	-179.3	-125.6	12.7	0	0	0	112.5	F60 T64	F60-N62 PolarHBondContact O-N 3.46Å; N62-T64 PolarHBondContact O-N 3.3Å
63	P	45.5	Very low	56	Low	115 Å²	115	85.9 Å²	85.9	75%	0.747	50%	0.5	S	S	*	.			trans	-87.2	16.9	178.8	-4.7	24.6	0	0	0	115	A61	A61-P63 WeakPolarHBondContact O-CD 3.4Å
64	T	50.6	Low	57.8	Low	75 Å²	75	82.5 Å²	82.5	46%	0.46	46%	0.463	S	S	.	.			trans	-134.4	8.3	-158.2	50.7	0	0	0	0	119.5	N62	N62-T64 PolarHBondContact O-N 3.3Å
65	D	55.2	Low	60.2	Low	124 Å²	124	82.7 Å²	82.7	66%	0.663	45%	0.454	S	S	*	.			trans	-101.9	-7.7	177	-83.7	-10.3	0	0	0	114.9	T67	D65-T67 PolarHBondContact O-N 3.27Å
66	D	68.1	Low	62.5	Low	61 Å²	61	79.7 Å²	79.7	33%	0.326	43%	0.429	S	S	.	.			trans	-68.5	132.4	175.8	-67.8	-24.3	0	0	0	109	G292 K293	D66-G292 CarbonylContact O-C 3.45Å; D66-G292 VanDerWaalsContact O-C 3.31Å; D66-G292 WeakPolarHBondContact O-CA 3.24Å; D66-K293 PolarHBondContact O-N 3.13Å
67	T	79.3	Confident	65	Low	65 Å²	65	75.9 Å²	75.9	40%	0.399	41%	0.405	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.6	141	176.8	57.2	0	0	0	0	109.3	D65 K293 I295	D65-T67 PolarHBondContact O-N 3.27Å; T67-K293 VanDerWaalsContact CA-O 3.28Å; T67-K293 WeakPolarHBondContact CA-O 3.42Å; T67-K293 HydrophobicContact CG2-CB 4.44Å; T67-I295 HydrophobicContact CG2-CG2 3.77Å
68	F	82.9	Confident	67.6	Low	16 Å²	16	73 Å²	73	7%	0.07	39%	0.39	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.3	153	176.1	65.8	-94.8	0	0	0	110.9	D72 A73 L278 M289 P290 G292 K293 L294 I295	F68-D72 HydrophobicContact CB-CB 4.48Å; F68-A73 HydrophobicContact CD2-CB 3.94Å; F68-A73 HydrophobicContact CE2-CB 3.98Å; F68-L278 HydrophobicContact CE2-CD1 4.38Å; F68-M289 HydrophobicContact CE2-CE 3.86Å; F68-M289 HydrophobicContact CZ-CE 3.67Å; F68-P290 HydrophobicContact CD1-CB 4.25Å; F68-P290 HydrophobicContact CD1-CG 4.27Å; F68-P290 HydrophobicContact CD2-CG 3.92Å; F68-P290 HydrophobicContact CE1-CG 4.29Å; F68-P290 HydrophobicContact CE2-CG 3.96Å; F68-P290 HydrophobicContact CG-CB 4.26Å; F68-P290 HydrophobicContact CG-CG 4.09Å; F68-P290 HydrophobicContact CZ-CG 4.16Å; F68-G292 VanDerWaalsContact CE1-O 3.23Å; F68-G292 WeakPolarHBondContact CE1-O 3.41Å; F68-K293 PolarHBondContact N-O 2.97Å; F68-K293 VanDerWaalsContact N-O 3.12Å; F68-L294 HydrophobicContact CD2-CD1 4.08Å; F68-L294 HydrophobicContact CE2-CB 4.4Å; F68-L294 HydrophobicContact CE2-CD1 3.82Å; F68-L294 HydrophobicContact CZ-CB 4.42Å; F68-L294 WeakPolarHBondContact O-CA 3.33Å; F68-I295 PolarHBondContact O-N 3.17Å; F68-I295 VanDerWaalsContact O-N 3.07Å
69	M	85.6	Confident	70	Confident	62 Å²	62	67.3 Å²	67.3	31%	0.305	37%	0.365	S	S	.	.			trans	-95.1	166.1	173.6	-56	-166.2	179.8	0	0	111.4	E71 D72 A73 I295	M69-E71 PolarHBondContact O-N 3.12Å; M69-D72 WeakPolarHBondContact CB-OD2 3.4Å; M69-D72 PolarHBondContact N-OD2 3.2Å; M69-D72 PolarHBondContact O-N 3.27Å; M69-A73 PolarHBondContact O-N 2.8Å; M69-I295 HydrophobicContact CE-CD1 3.86Å; M69-I295 HydrophobicContact CE-CG1 4.5Å; M69-I295 HydrophobicContact CG-CD1 4.25Å; M69-I295 HydrophobicContact CG-CG1 4.05Å
70	V	84.8	Confident	72.6	Confident	9 Å²	9	59.5 Å²	59.5	6%	0.055	33%	0.334	C	S	.	.	H	α-helix	trans	-58.7	-41.6	176.3	178.5	0	0	0	0	110.3	A73 V74 A262 V266 L278 L294	V70-A73 PolarHBondContact O-N 2.72Å; V70-V74 HydrophobicContact CG1-CG2 4.46Å; V70-V74 WeakPolarHBondContact O-CG2 3.38Å; V70-V74 PolarHBondContact O-N 2.86Å; V70-A262 HydrophobicContact CG1-CB 3.9Å; V70-V266 HydrophobicContact CG2-CB 4.35Å; V70-V266 HydrophobicContact CG2-CG2 3.68Å; V70-L278 HydrophobicContact CG1-CD2 4.46Å; V70-L294 HydrophobicContact CG2-CD1 3.91Å
71	E	83.1	Confident	75.3	Confident	75 Å²	75	59.1 Å²	59.1	35%	0.35	33%	0.332	S	S	.	.	H	α-helix	trans	-61.7	-44	178.9	-65.1	78.8	-175.1	0	0	111.7	M69 A73 V74 E75 R263	M69-E71 PolarHBondContact O-N 3.12Å; E71-A73 VanDerWaalsContact C-N 3.32Å; E71-A73 PolarHBondContact O-N 3.18Å; E71-V74 PolarHBondContact O-N 3.45Å; E71-E75 PolarHBondContact O-N 3.12Å; E71-R263 IonicContact OE1-CZ 3.96Å; E71-R263 IonicContact OE1-NE 3.67Å; E71-R263 PolarHBondContact OE1-NE 3.3Å; E71-R263 IonicContact OE1-NH2 3.55Å
72	D	83.6	Confident	78.3	Confident	78 Å²	78	56.6 Å²	56.6	42%	0.417	31%	0.311	S	S	.	.	H	α-helix	trans	-63.5	-39.7	177	-55.2	-39.4	0	0	0	111.3	F68 M69 E75 A76	F68-D72 HydrophobicContact CB-CB 4.48Å; M69-D72 WeakPolarHBondContact CB-OD2 3.4Å; M69-D72 PolarHBondContact N-OD2 3.2Å; M69-D72 PolarHBondContact O-N 3.27Å; D72-E75 PolarHBondContact O-N 3.38Å; D72-A76 VanDerWaalsContact O-CB 3.29Å; D72-A76 WeakPolarHBondContact O-CB 3.49Å; D72-A76 PolarHBondContact O-N 3.35Å
73	A	85.7	Confident	81	Confident	0 Å²	0	51.1 Å²	51.1	0%	0	28%	0.281	C	S	.	.	H	α-helix	trans	-66.3	-43.1	177.5	0	0	0	0	0	112.2	F68 M69 V70 E71 E75 A76 I77 L278 P290	F68-A73 HydrophobicContact CD2-CB 3.94Å; F68-A73 HydrophobicContact CE2-CB 3.98Å; M69-A73 PolarHBondContact O-N 2.8Å; V70-A73 PolarHBondContact O-N 2.72Å; E71-A73 VanDerWaalsContact C-N 3.32Å; E71-A73 PolarHBondContact O-N 3.18Å; A73-E75 VanDerWaalsContact C-N 3.34Å; A73-A76 PolarHBondContact O-N 2.81Å; A73-I77 WeakPolarHBondContact O-CB 3.44Å; A73-I77 WeakPolarHBondContact O-CD1 3.28Å; A73-I77 WeakPolarHBondContact O-CG1 3.45Å; A73-I77 PolarHBondContact O-N 3.38Å; A73-L278 HydrophobicContact CB-CD1 3.92Å; A73-L278 HydrophobicContact CB-CD2 4.05Å; A73-P290 HydrophobicContact CB-CG 3.77Å
74	V	87.4	Confident	83.2	Confident	9 Å²	9	52.2 Å²	52.2	6%	0.055	27%	0.271	C	S	.	.	H	α-helix	trans	-65.5	-38.3	176.8	173.4	0	0	0	0	111	V70 E71 G78 L278	V70-V74 HydrophobicContact CG1-CG2 4.46Å; V70-V74 WeakPolarHBondContact O-CG2 3.38Å; V70-V74 PolarHBondContact O-N 2.86Å; E71-V74 PolarHBondContact O-N 3.45Å; V74-G78 PolarHBondContact O-N 3.27Å; V74-L278 HydrophobicContact CG2-CD2 4.11Å
75	E	86.9	Confident	85.2	Confident	66 Å²	66	53.5 Å²	53.5	31%	0.308	27%	0.27	S	S	.	.	H	α-helix	trans	-67.2	-41	175.7	-169.9	68.6	-161	0	0	111.7	E71 D72 A73 G78 P202 M203 K204	E71-E75 PolarHBondContact O-N 3.12Å; D72-E75 PolarHBondContact O-N 3.38Å; A73-E75 VanDerWaalsContact C-N 3.34Å; E75-G78 PolarHBondContact O-N 3.46Å; E75-P202 WeakPolarHBondContact OE2-CA 3.41Å; E75-P202 VanDerWaalsContact OE2-CB 3.28Å; E75-P202 WeakPolarHBondContact OE2-CB 3.28Å; E75-M203 PolarHBondContact OE2-N 3.46Å; E75-K204 WeakPolarHBondContact OE1-CE 3.49Å; E75-K204 IonicContact OE1-NZ 3.41Å
76	A	85.7	Confident	86.9	Confident	35 Å²	35	47.6 Å²	47.6	29%	0.289	24%	0.238	S	C	.	.	H	α-helix	trans	-67	-41.5	177.4	0	0	0	0	0	113.1	F16 D72 A73 G78	F16-A76 HydrophobicContact CE2-CB 3.65Å; F16-A76 HydrophobicContact CZ-CB 4.16Å; D72-A76 VanDerWaalsContact O-CB 3.29Å; D72-A76 WeakPolarHBondContact O-CB 3.49Å; D72-A76 PolarHBondContact O-N 3.35Å; A73-A76 PolarHBondContact O-N 2.81Å; A76-G78 VanDerWaalsContact C-N 3.3Å
77	I	88.6	Confident	88.1	Confident	10 Å²	10	44.7 Å²	44.7	5%	0.051	22%	0.223	C	C	.	.	H	α-helix	trans	-68.9	-32.9	177.2	-68.9	164.1	0	0	0	110.9	A73 L278 I281 A282 N285 A287 M289	A73-I77 WeakPolarHBondContact O-CB 3.44Å; A73-I77 WeakPolarHBondContact O-CD1 3.28Å; A73-I77 WeakPolarHBondContact O-CG1 3.45Å; A73-I77 PolarHBondContact O-N 3.38Å; I77-L278 HydrophobicContact CD1-CD2 4.5Å; I77-I281 HydrophobicContact CD1-CB 4.49Å; I77-I281 HydrophobicContact CG2-CB 4.48Å; I77-I281 HydrophobicContact CG2-CG2 3.69Å; I77-A282 HydrophobicContact CD1-CB 3.98Å; I77-A282 HydrophobicContact CG1-CB 4.07Å; I77-N285 HydrophobicContact CG2-CB 4.19Å; I77-A287 HydrophobicContact CB-CB 4.48Å; I77-A287 HydrophobicContact CG2-CB 4.12Å; I77-A287 WeakPolarHBondContact O-CB 3.26Å; I77-M289 HydrophobicContact CD1-SD 4.48Å
78	G	87.6	Confident	88.7	Confident	19 Å²	19	45 Å²	45	20%	0.196	23%	0.225	C	C	.	.			trans	70.9	-171.5	177.8	0	0	0	0	0	114.1	V74 E75 A76 Q83 N285	V74-G78 PolarHBondContact O-N 3.27Å; E75-G78 PolarHBondContact O-N 3.46Å; A76-G78 VanDerWaalsContact C-N 3.3Å; G78-Q83 PolarHBondContact O-NE2 3.29Å; G78-N285 PolarHBondContact O-ND2 3.4Å
79	F	89.9	Confident	89.2	Confident	78 Å²	78	44.6 Å²	44.6	34%	0.342	22%	0.223	S	C	.	.	S	Bend	trans	-92.1	127.8	-178.5	-175	-85.1	0	0	0	111	Q83 W84 L201 P202 A205 C209	F79-Q83 HydrophobicContact CD2-CB 3.61Å; F79-Q83 HydrophobicContact CD2-CG 4Å; F79-Q83 HydrophobicContact CE2-CB 3.44Å; F79-Q83 VanDerWaalsContact CE2-CB 3.44Å; F79-Q83 HydrophobicContact CE2-CG 4.29Å; F79-Q83 HydrophobicContact CG-CB 4.35Å; F79-Q83 HydrophobicContact CZ-CB 4.05Å; F79-W84 AromaticContact CE1-CD1 3.49Å; F79-W84 VanDerWaalsContact CE1-CD1 3.49Å; F79-W84 HydrophobicContact CE1-CG 4.28Å; F79-W84 AromaticContact CE1-NE1 3.46Å; F79-W84 AromaticContact CZ-CD1 3.87Å; F79-W84 HydrophobicContact CZ-CD2 4.47Å; F79-W84 HydrophobicContact CZ-CG 4.24Å; F79-W84 AromaticContact CZ-NE1 3.91Å; F79-L201 HydrophobicContact CD2-CD2 3.77Å; F79-L201 HydrophobicContact CE2-CD2 3.76Å; F79-P202 HydrophobicContact CB-CG 4.07Å; F79-A205 HydrophobicContact CD2-CB 4.47Å; F79-C209 VanDerWaalsContact CE2-SG 3.57Å
80	G	91.4	Very high	89.5	Confident	18 Å²	18	41.7 Å²	41.7	19%	0.186	21%	0.209	C	C	.	.			trans	-151.5	-153	-178.3	0	0	0	0	0	113.9	F82 Q83 W84 N285	G80-F82 VanDerWaalsContact C-N 3.29Å; G80-F82 PolarHBondContact O-N 3.01Å; G80-Q83 PolarHBondContact O-N 3.16Å; G80-Q83 PolarHBondContact O-OE1 3.24Å; G80-W84 PolarHBondContact O-N 2.97Å; G80-N285 VanDerWaalsContact C-OD1 3.27Å; G80-N285 VanDerWaalsContact CA-OD1 3.3Å; G80-N285 WeakPolarHBondContact CA-OD1 3.4Å
81	K	92.2	Very high	89.9	Confident	156 Å²	156	41.2 Å²	41.2	68%	0.678	21%	0.206	S	C	*	.	H	α-helix	trans	-63.5	-35	-175	-67.4	178.8	-178.2	173.5	0	112.2	W84 K85 N285	K81-W84 PolarHBondContact O-N 3.13Å; K81-K85 WeakPolarHBondContact O-CG 3.46Å; K81-K85 PolarHBondContact O-N 3.44Å; K81-N285 PolarHBondContact N-OD1 3.07Å
82	F	93.1	Very high	90.4	Very high	1 Å²	1	38.9 Å²	38.9	0%	0.004	20%	0.195	C	C	.	.	H	α-helix	trans	-60.8	-47.8	179.1	175.6	-90.5	0	0	0	111.3	G80 W84 K85 L86 F200 W257 P259 I281 E284 N285	G80-F82 VanDerWaalsContact C-N 3.29Å; G80-F82 PolarHBondContact O-N 3.01Å; F82-W84 PolarHBondContact O-N 3.07Å; F82-K85 PolarHBondContact O-N 3.41Å; F82-L86 HydrophobicContact CE1-CD2 4.21Å; F82-L86 WeakPolarHBondContact O-CB 3.23Å; F82-L86 PolarHBondContact O-N 2.93Å; F82-F200 HydrophobicContact CE1-CB 4.32Å; F82-F200 AromaticContact CE1-CD1 3.77Å; F82-F200 HydrophobicContact CE1-CD1 3.77Å; F82-F200 HydrophobicContact CE1-CE1 4.25Å; F82-F200 HydrophobicContact CE1-CG 4.09Å; F82-F200 HydrophobicContact CZ-CD1 4.2Å; F82-F200 HydrophobicContact CZ-CE1 4.2Å; F82-W257 HydrophobicContact CD2-CH2 4.01Å; F82-W257 HydrophobicContact CD2-CZ2 4.16Å; F82-W257 AromaticContact CE2-CH2 3.99Å; F82-W257 HydrophobicContact CE2-CH2 3.99Å; F82-W257 HydrophobicContact CE2-CZ2 4.27Å; F82-P259 HydrophobicContact CE2-CG 3.85Å; F82-P259 HydrophobicContact CZ-CG 3.5Å; F82-P259 VanDerWaalsContact CZ-CG 3.5Å; F82-I281 HydrophobicContact CB-CG2 4.38Å; F82-I281 HydrophobicContact CD1-CB 4.36Å; F82-I281 HydrophobicContact CD1-CG1 3.91Å; F82-I281 HydrophobicContact CD1-CG2 3.84Å; F82-I281 HydrophobicContact CD2-CG1 4.35Å; F82-I281 HydrophobicContact CE1-CD1 4.14Å; F82-I281 HydrophobicContact CE1-CG1 3.67Å; F82-I281 HydrophobicContact CE1-CG2 4.37Å; F82-I281 HydrophobicContact CE2-CG1 4.12Å; F82-I281 HydrophobicContact CG-CB 4.46Å; F82-I281 HydrophobicContact CG-CG1 4.23Å; F82-I281 HydrophobicContact CG-CG2 4.14Å; F82-I281 HydrophobicContact CZ-CD1 4.41Å; F82-I281 HydrophobicContact CZ-CG1 3.76Å; F82-E284 HydrophobicContact CB-CB 3.99Å; F82-N285 WeakPolarHBondContact CB-OD1 3.42Å; F82-N285 PolarHBondContact N-OD1 3.17Å
83	Q	93.1	Very high	90.9	Very high	1 Å²	1	35.1 Å²	35.1	1%	0.005	18%	0.176	C	C	.	.	H	α-helix	trans	-67.1	-36.1	-179.1	-67.7	85.2	-8.6	0	0	111.9	G78 F79 G80 L86 S87 L201 N285	G78-Q83 PolarHBondContact O-NE2 3.29Å; F79-Q83 HydrophobicContact CD2-CB 3.61Å; F79-Q83 HydrophobicContact CD2-CG 4Å; F79-Q83 HydrophobicContact CE2-CB 3.44Å; F79-Q83 VanDerWaalsContact CE2-CB 3.44Å; F79-Q83 HydrophobicContact CE2-CG 4.29Å; F79-Q83 HydrophobicContact CG-CB 4.35Å; F79-Q83 HydrophobicContact CZ-CB 4.05Å; G80-Q83 PolarHBondContact O-N 3.16Å; G80-Q83 PolarHBondContact O-OE1 3.24Å; Q83-L86 PolarHBondContact O-N 3.45Å; Q83-S87 VanDerWaalsContact O-CB 3.31Å; Q83-S87 WeakPolarHBondContact O-CB 3.4Å; Q83-S87 PolarHBondContact O-N 2.84Å; Q83-L201 HydrophobicContact CB-CD2 4.38Å; Q83-L201 HydrophobicContact CG-CD2 4.29Å; Q83-N285 PolarHBondContact NE2-ND2 3.16Å; Q83-N285 PolarHBondContact OE1-ND2 3.43Å; Q83-N285 PolarHBondContact OE1-OD1 3.41Å
84	W	91.8	Very high	91.2	Very high	139 Å²	139	35.8 Å²	35.8	53%	0.527	18%	0.178	S	C	.	.	H	α-helix	trans	-61.8	-46.8	172.5	-95.5	115	0	0	0	112.6	F79 G80 K81 F82 L86 S87 V88 L212	F79-W84 AromaticContact CE1-CD1 3.49Å; F79-W84 VanDerWaalsContact CE1-CD1 3.49Å; F79-W84 HydrophobicContact CE1-CG 4.28Å; F79-W84 AromaticContact CE1-NE1 3.46Å; F79-W84 AromaticContact CZ-CD1 3.87Å; F79-W84 HydrophobicContact CZ-CD2 4.47Å; F79-W84 HydrophobicContact CZ-CG 4.24Å; F79-W84 AromaticContact CZ-NE1 3.91Å; G80-W84 PolarHBondContact O-N 2.97Å; K81-W84 PolarHBondContact O-N 3.13Å; F82-W84 PolarHBondContact O-N 3.07Å; W84-L86 VanDerWaalsContact C-N 3.32Å; W84-L86 PolarHBondContact O-N 3.4Å; W84-S87 WeakPolarHBondContact O-CB 2.86Å; W84-S87 PolarHBondContact O-N 3.43Å; W84-V88 PolarHBondContact O-N 2.7Å; W84-V88 VanDerWaalsContact O-N 3.09Å; W84-L212 HydrophobicContact CH2-CD2 3.8Å; W84-L212 HydrophobicContact CZ3-CD2 3.98Å
85	K	92.9	Very high	91.6	Very high	102 Å²	102	36.3 Å²	36.3	44%	0.443	18%	0.18	S	C	.	.	H	α-helix	trans	-60.5	-43.9	175.8	-70.7	176.2	-171.7	170.3	0	111.5	K81 F82 S87 V88 L89 W257 E284	K81-K85 WeakPolarHBondContact O-CG 3.46Å; K81-K85 PolarHBondContact O-N 3.44Å; F82-K85 PolarHBondContact O-N 3.41Å; K85-S87 VanDerWaalsContact C-N 3.33Å; K85-V88 PolarHBondContact O-N 3.31Å; K85-L89 PolarHBondContact O-N 3.32Å; K85-L89 VanDerWaalsContact O-N 3.13Å; K85-W257 HydrophobicContact CB-CH2 3.56Å; K85-W257 HydrophobicContact CB-CZ2 4.06Å; K85-W257 HydrophobicContact CB-CZ3 4.05Å; K85-W257 HydrophobicContact CD-CH2 4.06Å; K85-W257 HydrophobicContact CD-CZ2 3.69Å; K85-E284 IonicContact NZ-OE2 3.77Å; K85-E284 PolarHBondContact NZ-OE2 3.22Å
86	L	92.3	Very high	91.9	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-62.1	-42.9	177.2	-176.7	65	0	0	0	111.3	F82 Q83 W84 V88 L89 T90 Y197 F200 L258	F82-L86 HydrophobicContact CE1-CD2 4.21Å; F82-L86 WeakPolarHBondContact O-CB 3.23Å; F82-L86 PolarHBondContact O-N 2.93Å; Q83-L86 PolarHBondContact O-N 3.45Å; W84-L86 VanDerWaalsContact C-N 3.32Å; W84-L86 PolarHBondContact O-N 3.4Å; L86-V88 PolarHBondContact O-N 2.92Å; L86-L89 PolarHBondContact O-N 3.04Å; L86-T90 HydrophobicContact CD1-CG2 4.13Å; L86-T90 HydrophobicContact CG-CG2 4.4Å; L86-T90 PolarHBondContact O-N 3.35Å; L86-T90 PolarHBondContact O-OG1 3.48Å; L86-Y197 HydrophobicContact CB-CD2 4.45Å; L86-Y197 HydrophobicContact CD2-CD2 3.88Å; L86-Y197 HydrophobicContact CG-CD2 3.92Å; L86-F200 HydrophobicContact CD2-CB 3.62Å; L86-F200 HydrophobicContact CD2-CD2 3.32Å; L86-F200 HydrophobicContact CD2-CE2 4.1Å; L86-F200 HydrophobicContact CD2-CG 3.65Å; L86-L258 HydrophobicContact CD1-CD1 3.35Å
87	S	92.3	Very high	92.3	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-58.6	-45.4	178	-174.8	0	0	0	0	112.3	Q83 W84 K85 L89 T90 G91 Y197	Q83-S87 VanDerWaalsContact O-CB 3.31Å; Q83-S87 WeakPolarHBondContact O-CB 3.4Å; Q83-S87 PolarHBondContact O-N 2.84Å; W84-S87 WeakPolarHBondContact O-CB 2.86Å; W84-S87 PolarHBondContact O-N 3.43Å; K85-S87 VanDerWaalsContact C-N 3.33Å; S87-L89 VanDerWaalsContact C-N 3.34Å; S87-T90 PolarHBondContact O-OG1 3.04Å; S87-G91 WeakPolarHBondContact O-CA 3.33Å; S87-G91 PolarHBondContact O-N 3.38Å; S87-Y197 WeakPolarHBondContact CB-OH 3.36Å; S87-Y197 PolarHBondContact OG-OH 3.28Å
88	V	92.6	Very high	92.6	Very high	72 Å²	72	31.2 Å²	31.2	44%	0.436	15%	0.151	S	C	.	.	H	α-helix	trans	-62.4	-44.3	176.6	173.8	0	0	0	0	110.4	W84 K85 L86 G91 L92	W84-V88 PolarHBondContact O-N 2.7Å; W84-V88 VanDerWaalsContact O-N 3.09Å; K85-V88 PolarHBondContact O-N 3.31Å; L86-V88 PolarHBondContact O-N 2.92Å; V88-G91 PolarHBondContact O-N 3.46Å; V88-L92 WeakPolarHBondContact O-CG 3.34Å; V88-L92 PolarHBondContact O-N 2.99Å
89	L	92.5	Very high	93	Very high	7 Å²	7	30.4 Å²	30.4	4%	0.037	14%	0.142	C	C	.	.	H	α-helix	trans	-65.9	-49	-179.1	-174.2	57.2	0	0	0	112.2	K85 L86 S87 G91 L92 F251 L254 W257 L258	K85-L89 PolarHBondContact O-N 3.32Å; K85-L89 VanDerWaalsContact O-N 3.13Å; L86-L89 PolarHBondContact O-N 3.04Å; S87-L89 VanDerWaalsContact C-N 3.34Å; L89-G91 VanDerWaalsContact C-N 3.28Å; L89-G91 PolarHBondContact O-N 3.03Å; L89-L92 PolarHBondContact O-N 2.91Å; L89-F251 HydrophobicContact CD1-CD2 3.71Å; L89-F251 HydrophobicContact CD1-CE2 3.91Å; L89-F251 HydrophobicContact CD1-CG 4.46Å; L89-F251 HydrophobicContact CG-CD2 4.2Å; L89-F251 HydrophobicContact CG-CE2 3.91Å; L89-F251 WeakPolarHBondContact O-CD2 3.48Å; L89-F251 VanDerWaalsContact O-CE2 3.24Å; L89-F251 WeakPolarHBondContact O-CE2 3.34Å; L89-L254 HydrophobicContact CD1-CB 3.47Å; L89-L254 VanDerWaalsContact CD1-CB 3.47Å; L89-L254 HydrophobicContact CD1-CD1 4.42Å; L89-W257 HydrophobicContact CD2-CE3 4.02Å; L89-L258 HydrophobicContact CD2-CB 3.93Å; L89-L258 HydrophobicContact CD2-CD1 3.78Å; L89-L258 HydrophobicContact CD2-CG 4.37Å; L89-L258 HydrophobicContact CG-CD1 4.48Å
90	T	92.1	Very high	93.2	Very high	0 Å²	0	27 Å²	27	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-68.1	-30.9	176.2	54.7	0	0	0	0	112.2	L86 S87 A93 W94	L86-T90 HydrophobicContact CD1-CG2 4.13Å; L86-T90 HydrophobicContact CG-CG2 4.4Å; L86-T90 PolarHBondContact O-N 3.35Å; L86-T90 PolarHBondContact O-OG1 3.48Å; S87-T90 PolarHBondContact O-OG1 3.04Å; T90-A93 PolarHBondContact O-N 2.99Å; T90-W94 PolarHBondContact O-N 3.13Å
91	G	93.2	Very high	93.2	Very high	0 Å²	0	26.6 Å²	26.6	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-64.9	-36.3	175.1	0	0	0	0	0	112.8	S87 V88 L89 A93 W94 M95	S87-G91 WeakPolarHBondContact O-CA 3.33Å; S87-G91 PolarHBondContact O-N 3.38Å; V88-G91 PolarHBondContact O-N 3.46Å; L89-G91 VanDerWaalsContact C-N 3.28Å; L89-G91 PolarHBondContact O-N 3.03Å; G91-A93 VanDerWaalsContact C-N 3.31Å; G91-A93 PolarHBondContact O-N 3.1Å; G91-W94 PolarHBondContact O-N 3.19Å; G91-M95 VanDerWaalsContact O-CB 3.31Å; G91-M95 WeakPolarHBondContact O-CB 3.37Å; G91-M95 PolarHBondContact O-N 3.38Å
92	L	93.5	Very high	93.4	Very high	25 Å²	25	19.3 Å²	19.3	13%	0.131	9%	0.089	C	C	.	.	H	α-helix	trans	-61	-38.6	173	-74	172.1	0	0	0	112.6	V88 L89 M95 A96 F251 L254	V88-L92 WeakPolarHBondContact O-CG 3.34Å; V88-L92 PolarHBondContact O-N 2.99Å; L89-L92 PolarHBondContact O-N 2.91Å; L92-M95 HydrophobicContact CD2-SD 4.33Å; L92-A96 WeakPolarHBondContact O-CB 3.3Å; L92-A96 PolarHBondContact O-N 3.34Å; L92-F251 HydrophobicContact CB-CB 4.5Å; L92-F251 HydrophobicContact CB-CD2 4.44Å; L92-L254 HydrophobicContact CD1-CD1 4.03Å
93	A	93.6	Very high	93.5	Very high	0 Å²	0	19.3 Å²	19.3	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-67.3	-39.5	175.3	0	0	0	0	0	111.6	T90 G91 A96 D97 L153 V157 V190 F251	T90-A93 PolarHBondContact O-N 2.99Å; G91-A93 VanDerWaalsContact C-N 3.31Å; G91-A93 PolarHBondContact O-N 3.1Å; A93-A96 PolarHBondContact O-N 3.5Å; A93-D97 PolarHBondContact O-N 3.2Å; A93-D97 VanDerWaalsContact O-N 3.12Å; A93-L153 HydrophobicContact CB-CD1 4.5Å; A93-V157 HydrophobicContact CB-CG2 4.36Å; A93-V190 HydrophobicContact CB-CG1 4.24Å; A93-V190 WeakPolarHBondContact O-CG1 3.4Å; A93-F251 HydrophobicContact CB-CD2 3.96Å; A93-F251 HydrophobicContact CB-CE2 3.94Å; A93-F251 HydrophobicContact CB-CZ 4.49Å
94	W	92.7	Very high	93.5	Very high	13 Å²	13	19.4 Å²	19.4	5%	0.049	9%	0.089	C	C	.	.	H	α-helix	trans	-67.7	-40.5	176.3	-160.3	-114.3	0	0	0	112.6	T90 G91 A96 D97 A98 V190 P191 V194 I213 E214 W217	T90-W94 PolarHBondContact O-N 3.13Å; G91-W94 PolarHBondContact O-N 3.19Å; W94-A96 VanDerWaalsContact C-N 3.33Å; W94-A96 PolarHBondContact O-N 2.84Å; W94-D97 PolarHBondContact O-N 2.87Å; W94-A98 PolarHBondContact O-N 3.37Å; W94-V190 HydrophobicContact CE3-CG1 3.98Å; W94-V190 HydrophobicContact CZ3-CG1 4.44Å; W94-P191 HydrophobicContact CZ3-CG 4.46Å; W94-V194 HydrophobicContact CD2-CG2 4.27Å; W94-V194 HydrophobicContact CE3-CG2 3.86Å; W94-V194 HydrophobicContact CH2-CG2 4.45Å; W94-V194 HydrophobicContact CZ3-CG2 3.98Å; W94-I213 HydrophobicContact CB-CG2 4.07Å; W94-I213 VanDerWaalsContact CD1-O 3.27Å; W94-I213 HydrophobicContact CD2-CG2 4.15Å; W94-I213 HydrophobicContact CG-CG2 3.64Å; W94-E214 PolarHBondContact NE1-OE2 3.08Å; W94-W217 HydrophobicContact CD2-CE3 4.35Å; W94-W217 AromaticContact CE2-CE3 3.73Å; W94-W217 AromaticContact CZ2-CE3 3.96Å; W94-W217 HydrophobicContact CZ2-CE3 3.96Å; W94-W217 HydrophobicContact CZ2-CZ3 4.26Å; W94-W217 AromaticContact NE1-CE3 3.7Å
95	M	94.9	Very high	93.5	Very high	20 Å²	20	12.8 Å²	12.8	10%	0.099	6%	0.064	C	C	.	.	H	α-helix	trans	-59.3	-44.3	172.7	177	-171.9	155.1	0	0	111.2	G91 L92 A98 M99 F216 I219 F223 P247	G91-M95 VanDerWaalsContact O-CB 3.31Å; G91-M95 WeakPolarHBondContact O-CB 3.37Å; G91-M95 PolarHBondContact O-N 3.38Å; L92-M95 HydrophobicContact CD2-SD 4.33Å; M95-A98 WeakPolarHBondContact O-CB 3.16Å; M95-A98 PolarHBondContact O-N 3.48Å; M95-M99 HydrophobicContact CE-SD 3.78Å; M95-M99 HydrophobicContact CG-SD 4.36Å; M95-M99 WeakPolarHBondContact O-CG 3.37Å; M95-M99 PolarHBondContact O-N 2.92Å; M95-F216 WeakPolarHBondContact CA-O 3.31Å; M95-F216 HydrophobicContact CB-CB 4.39Å; M95-I219 HydrophobicContact SD-CG2 4.21Å; M95-F223 HydrophobicContact CE-CB 4.28Å; M95-F223 HydrophobicContact CE-CD1 3.8Å; M95-F223 HydrophobicContact CE-CE1 4.29Å; M95-F223 HydrophobicContact CE-CG 4Å; M95-P247 HydrophobicContact CE-CB 4.21Å; M95-P247 HydrophobicContact CE-CG 3.6Å
96	A	94.3	Very high	93.5	Very high	2 Å²	2	8 Å²	8	2%	0.017	4%	0.043	C	C	.	.	H	α-helix	trans	-64.3	-38.8	177.6	0	0	0	0	0	113.4	L92 A93 W94 M99 E100 P247 L248	L92-A96 WeakPolarHBondContact O-CB 3.3Å; L92-A96 PolarHBondContact O-N 3.34Å; A93-A96 PolarHBondContact O-N 3.5Å; W94-A96 VanDerWaalsContact C-N 3.33Å; W94-A96 PolarHBondContact O-N 2.84Å; A96-M99 PolarHBondContact O-N 3.42Å; A96-E100 PolarHBondContact O-N 2.93Å; A96-P247 HydrophobicContact CB-CB 4.31Å; A96-L248 HydrophobicContact CB-CD1 4.45Å; A96-L248 HydrophobicContact CB-CD2 3.35Å; A96-L248 HydrophobicContact CB-CG 3.56Å
97	D	93.6	Very high	93.5	Very high	3 Å²	3	8 Å²	8	2%	0.016	4%	0.044	C	C	.	.	H	α-helix	trans	-59.8	-47.5	172.8	-176.6	19	0	0	0	110.8	A93 W94 M99 E100 M101 I187 V190 W217	A93-D97 PolarHBondContact O-N 3.2Å; A93-D97 VanDerWaalsContact O-N 3.12Å; W94-D97 PolarHBondContact O-N 2.87Å; D97-M99 VanDerWaalsContact C-N 3.3Å; D97-M99 PolarHBondContact O-N 3.48Å; D97-E100 PolarHBondContact O-N 3.25Å; D97-M101 WeakPolarHBondContact O-CG 2.98Å; D97-M101 PolarHBondContact O-N 3.44Å; D97-I187 WeakPolarHBondContact OD1-CG2 3.32Å; D97-V190 HydrophobicContact CB-CB 4.36Å; D97-V190 HydrophobicContact CB-CG1 3.97Å; D97-V190 HydrophobicContact CB-CG2 4.42Å; D97-W217 HydrophobicContact CB-CZ3 4.38Å
98	A	94.4	Very high	93.4	Very high	0 Å²	0	8.1 Å²	8.1	0%	0	4%	0.044	C	C	.	.	H	α-helix	trans	-59.7	-39	176.7	0	0	0	0	0	113.1	W94 M95 M101 M102 W217 T221	W94-A98 PolarHBondContact O-N 3.37Å; M95-A98 WeakPolarHBondContact O-CB 3.16Å; M95-A98 PolarHBondContact O-N 3.48Å; A98-M101 PolarHBondContact O-N 3.25Å; A98-M102 WeakPolarHBondContact O-CB 3.25Å; A98-M102 PolarHBondContact O-N 3.4Å; A98-W217 HydrophobicContact CB-CB 4.28Å; A98-W217 HydrophobicContact CB-CD2 3.52Å; A98-W217 HydrophobicContact CB-CE3 3.7Å; A98-W217 HydrophobicContact CB-CG 3.79Å; A98-W217 HydrophobicContact CB-CZ2 4.42Å; A98-W217 HydrophobicContact CB-CZ3 4.23Å; A98-W217 VanDerWaalsContact CB-O 3.3Å; A98-W217 WeakPolarHBondContact CB-O 3.34Å; A98-T221 HydrophobicContact CB-CG2 4.13Å
99	M	95.8	Very high	93.1	Very high	1 Å²	1	4.8 Å²	4.8	1%	0.005	2%	0.024	C	C	.	.	H	α-helix	trans	-65.1	-45.9	175.2	-70.9	177.7	63.8	0	0	112.2	M95 A96 D97 M101 M102 I103 G220 F223 E224 P247	M95-M99 HydrophobicContact CE-SD 3.78Å; M95-M99 HydrophobicContact CG-SD 4.36Å; M95-M99 WeakPolarHBondContact O-CG 3.37Å; M95-M99 PolarHBondContact O-N 2.92Å; A96-M99 PolarHBondContact O-N 3.42Å; D97-M99 VanDerWaalsContact C-N 3.3Å; D97-M99 PolarHBondContact O-N 3.48Å; M99-M101 PolarHBondContact O-N 2.88Å; M99-M102 PolarHBondContact O-N 2.92Å; M99-M102 VanDerWaalsContact O-N 3.14Å; M99-I103 WeakPolarHBondContact O-CB 3.32Å; M99-I103 PolarHBondContact O-N 3.34Å; M99-G220 WeakPolarHBondContact CG-O 3.28Å; M99-F223 HydrophobicContact CE-CD1 3.54Å; M99-F223 HydrophobicContact CE-CE1 3.88Å; M99-F223 HydrophobicContact SD-CD1 3.67Å; M99-F223 HydrophobicContact SD-CE1 4.31Å; M99-E224 HydrophobicContact CB-CB 4.31Å; M99-E224 WeakPolarHBondContact CE-OE2 3.33Å; M99-E224 HydrophobicContact CG-CB 4.1Å; M99-P247 HydrophobicContact CE-CG 4.27Å; M99-P247 HydrophobicContact SD-CG 3.6Å
100	E	94.6	Very high	93	Very high	6 Å²	6	5.8 Å²	5.8	3%	0.028	3%	0.028	C	C	.	.	H	α-helix	trans	-65.8	-25.8	176.4	-73.1	-71.3	172.7	0	0	112.7	A96 D97 I103 L104 R180 V183 I187	A96-E100 PolarHBondContact O-N 2.93Å; D97-E100 PolarHBondContact O-N 3.25Å; E100-I103 VanDerWaalsContact O-CG2 3.31Å; E100-I103 WeakPolarHBondContact O-CG2 3.5Å; E100-L104 WeakPolarHBondContact O-CG 3.34Å; E100-R180 IonicContact OE2-CZ 3.94Å; E100-R180 IonicContact OE2-NH1 3.32Å; E100-R180 PolarHBondContact OE2-NH1 2.88Å; E100-R180 VanDerWaalsContact OE2-NH1 3.14Å; E100-V183 HydrophobicContact CG-CG1 4.38Å; E100-I187 HydrophobicContact CB-CD1 3.52Å; E100-I187 HydrophobicContact CB-CG1 4.5Å; E100-I187 HydrophobicContact CG-CD1 4.05Å
101	M	92.6	Very high	92.9	Very high	11 Å²	11	5.8 Å²	5.8	5%	0.054	3%	0.028	C	C	.	.	H	α-helix	trans	-76	-38	171.2	-69.2	-48.9	-45.6	0	0	112.5	D97 A98 M99 L104 F130 W217 Y332	D97-M101 WeakPolarHBondContact O-CG 2.98Å; D97-M101 PolarHBondContact O-N 3.44Å; A98-M101 PolarHBondContact O-N 3.25Å; M99-M101 PolarHBondContact O-N 2.88Å; M101-L104 HydrophobicContact CE-CD1 4.13Å; M101-F130 HydrophobicContact CE-CD1 4.21Å; M101-F130 HydrophobicContact CE-CE1 3.16Å; M101-F130 HydrophobicContact CE-CE2 4.11Å; M101-F130 HydrophobicContact CE-CZ 3.13Å; M101-F130 HydrophobicContact SD-CE1 4.13Å; M101-W217 HydrophobicContact CB-CH2 4.36Å; M101-W217 HydrophobicContact CB-CZ2 4.4Å; M101-W217 HydrophobicContact CG-CH2 3.9Å; M101-W217 HydrophobicContact CG-CZ2 4.39Å; M101-Y332 HydrophobicContact CB-CE1 4.31Å; M101-Y332 HydrophobicContact CE-CD1 3.84Å; M101-Y332 HydrophobicContact CE-CE1 3.68Å; M101-Y332 HydrophobicContact CG-CE1 4.15Å
102	M	95.2	Very high	92.6	Very high	2 Å²	2	6.8 Å²	6.8	1%	0.01	3%	0.033	C	C	.	.	H	α-helix	trans	-72.5	-40.4	178.9	-179.6	59.9	74.8	0	0	112.4	A98 M99 L104 S105 T221 E224 V225 V335 T380	A98-M102 WeakPolarHBondContact O-CB 3.25Å; A98-M102 PolarHBondContact O-N 3.4Å; M99-M102 PolarHBondContact O-N 2.92Å; M99-M102 VanDerWaalsContact O-N 3.14Å; M102-L104 PolarHBondContact O-N 3.12Å; M102-S105 PolarHBondContact O-N 2.96Å; M102-S105 PolarHBondContact O-OG 3.25Å; M102-T221 HydrophobicContact CE-CG2 3.89Å; M102-E224 HydrophobicContact CB-CB 4.01Å; M102-E224 HydrophobicContact CB-CG 3.88Å; M102-E224 HydrophobicContact CG-CB 3.86Å; M102-E224 HydrophobicContact CG-CG 3.75Å; M102-V225 HydrophobicContact CE-CG2 4.31Å; M102-V225 HydrophobicContact CG-CG2 4Å; M102-V225 HydrophobicContact SD-CG2 4.02Å; M102-V335 HydrophobicContact CE-CG1 4.19Å; M102-V335 HydrophobicContact SD-CG1 3.86Å; M102-T380 HydrophobicContact CE-CG2 3.3Å; M102-T380 HydrophobicContact SD-CG2 4.33Å
103	I	95.2	Very high	92.3	Very high	1 Å²	1	5.9 Å²	5.9	1%	0.005	3%	0.029	C	C	.	.	H	α-helix	trans	-58.9	-26.6	-177.9	-163.3	164.4	0	0	0	112.1	M99 E100 S105 I106 L107 E224 L240 L241	M99-I103 WeakPolarHBondContact O-CB 3.32Å; M99-I103 PolarHBondContact O-N 3.34Å; E100-I103 VanDerWaalsContact O-CG2 3.31Å; E100-I103 WeakPolarHBondContact O-CG2 3.5Å; I103-S105 VanDerWaalsContact C-N 3.33Å; I103-S105 PolarHBondContact O-N 3.4Å; I103-I106 PolarHBondContact O-N 3.02Å; I103-L107 WeakPolarHBondContact O-CB 3.29Å; I103-L107 PolarHBondContact O-N 2.82Å; I103-E224 HydrophobicContact CB-CG 4.24Å; I103-E224 WeakPolarHBondContact CB-OE1 3.47Å; I103-E224 VanDerWaalsContact CD1-OE1 3.32Å; I103-E224 WeakPolarHBondContact CD1-OE1 3.32Å; I103-E224 VanDerWaalsContact CG1-OE1 3.29Å; I103-E224 WeakPolarHBondContact CG1-OE1 3.39Å; I103-L240 HydrophobicContact CD1-CD2 4.25Å; I103-L240 HydrophobicContact CD1-CG 3.98Å; I103-L240 HydrophobicContact CG1-CD2 4.1Å; I103-L240 HydrophobicContact CG1-CG 4.36Å; I103-L241 HydrophobicContact CD1-CD2 3.63Å; I103-L241 HydrophobicContact CD1-CG 4.31Å; I103-L241 HydrophobicContact CG1-CD2 4.48Å
104	L	93	Very high	92.1	Very high	4 Å²	4	10 Å²	10	2%	0.021	5%	0.048	C	C	.	.	H	α-helix	trans	-62.9	-35.5	177.2	-67.3	177.4	0	0	0	113.2	E100 M101 M102 I106 A108 T126 V129	E100-L104 WeakPolarHBondContact O-CG 3.34Å; M101-L104 HydrophobicContact CE-CD1 4.13Å; M102-L104 PolarHBondContact O-N 3.12Å; L104-I106 VanDerWaalsContact C-N 3.29Å; L104-I106 PolarHBondContact O-N 2.94Å; L104-A108 WeakPolarHBondContact O-CB 3.45Å; L104-A108 PolarHBondContact O-N 3.24Å; L104-A108 VanDerWaalsContact O-N 3.15Å; L104-T126 HydrophobicContact CB-CG2 4.05Å; L104-T126 HydrophobicContact CD2-CG2 4.48Å; L104-V129 HydrophobicContact CD1-CB 4.02Å; L104-V129 HydrophobicContact CD1-CG1 4.17Å; L104-V129 HydrophobicContact CD1-CG2 3.92Å; L104-V129 HydrophobicContact CD2-CG2 3.92Å
105	S	91.8	Very high	91.9	Very high	0 Å²	0	12.2 Å²	12.2	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-72.7	-25.2	178	67.2	0	0	0	0	112.7	M102 I103 P109 V335 T339	M102-S105 PolarHBondContact O-N 2.96Å; M102-S105 PolarHBondContact O-OG 3.25Å; I103-S105 VanDerWaalsContact C-N 3.33Å; I103-S105 PolarHBondContact O-N 3.4Å; S105-P109 WeakPolarHBondContact O-CD 3.36Å; S105-P109 WeakPolarHBondContact O-CG 3.47Å; S105-V335 WeakPolarHBondContact CB-O 3.4Å; S105-T339 WeakPolarHBondContact O-CB 3.33Å; S105-T339 WeakPolarHBondContact O-CG2 3.48Å; S105-T339 PolarHBondContact O-OG1 3.21Å
106	I	92.8	Very high	91.6	Very high	0 Å²	0	22 Å²	22	0%	0	9%	0.092	C	C	.	.	H	α-helix	trans	-88.8	-41.7	179.4	-56.9	176.8	0	0	0	110.8	I103 L104 P109 V225 A228 M232 L240 Y373 L376	I103-I106 PolarHBondContact O-N 3.02Å; L104-I106 VanDerWaalsContact C-N 3.29Å; L104-I106 PolarHBondContact O-N 2.94Å; I106-P109 WeakPolarHBondContact O-CD 3.31Å; I106-P109 WeakPolarHBondContact O-CG 3.33Å; I106-V225 HydrophobicContact CD1-CG2 4.47Å; I106-A228 HydrophobicContact CD1-CB 3.58Å; I106-A228 HydrophobicContact CG2-CB 4.27Å; I106-M232 HydrophobicContact CG2-CE 4.41Å; I106-M232 HydrophobicContact CG2-CG 4.45Å; I106-L240 HydrophobicContact CG2-CD2 4.06Å; I106-Y373 HydrophobicContact CG2-CE1 3.93Å; I106-L376 HydrophobicContact CD1-CD2 3.98Å; I106-L376 HydrophobicContact CG1-CD2 3.88Å
107	L	92.6	Very high	91.3	Very high	2 Å²	2	22.3 Å²	22.3	1%	0.01	9%	0.094	C	C	.	.	H	α-helix	trans	-72.8	-37.6	-176	-175.2	66.8	0	0	0	112.3	I103 Q110 L111 I176 W237 L241	I103-L107 WeakPolarHBondContact O-CB 3.29Å; I103-L107 PolarHBondContact O-N 2.82Å; L107-Q110 PolarHBondContact O-N 3.41Å; L107-L111 HydrophobicContact CD1-CD1 3.81Å; L107-L111 HydrophobicContact CD1-CD2 4.47Å; L107-L111 HydrophobicContact CD1-CG 3.95Å; L107-L111 HydrophobicContact CD2-CD1 4.12Å; L107-L111 HydrophobicContact CG-CD1 3.62Å; L107-L111 HydrophobicContact CG-CG 4.12Å; L107-L111 WeakPolarHBondContact O-CG 3.29Å; L107-L111 PolarHBondContact O-N 3.09Å; L107-I176 HydrophobicContact CD2-CD1 4.23Å; L107-W237 HydrophobicContact CD1-CB 3.86Å; L107-W237 HydrophobicContact CD1-CD2 4.13Å; L107-W237 HydrophobicContact CD1-CE3 3.77Å; L107-W237 HydrophobicContact CD1-CG 4.21Å; L107-L241 HydrophobicContact CD2-CD2 4.19Å
108	A	89.8	Confident	91.1	Very high	1 Å²	1	24.6 Å²	24.6	1%	0.008	11%	0.109	C	C	.	.	H	α-helix	trans	-54.4	-56.6	179.7	0	0	0	0	0	113.6	L104 Q110 L111 H112 V122 T126 Q480	L104-A108 WeakPolarHBondContact O-CB 3.45Å; L104-A108 PolarHBondContact O-N 3.24Å; L104-A108 VanDerWaalsContact O-N 3.15Å; A108-Q110 VanDerWaalsContact C-N 3.32Å; A108-Q110 PolarHBondContact O-N 3.21Å; A108-L111 PolarHBondContact O-N 3.41Å; A108-H112 WeakPolarHBondContact O-CB 3.49Å; A108-H112 PolarHBondContact O-N 2.75Å; A108-V122 HydrophobicContact CB-CG1 3.57Å; A108-T126 HydrophobicContact CB-CG2 4.09Å; A108-Q480 VanDerWaalsContact CB-NE2 3.29Å
109	P	86.9	Confident	90.7	Very high	2 Å²	2	25.1 Å²	25.1	1%	0.013	11%	0.112	C	C	.	.	H	α-helix	trans	-65.5	-33.8	178.7	22	-32.2	0	0	0	113.1	S105 I106 H112 C113 Q343 L368	S105-P109 WeakPolarHBondContact O-CD 3.36Å; S105-P109 WeakPolarHBondContact O-CG 3.47Å; I106-P109 WeakPolarHBondContact O-CD 3.31Å; I106-P109 WeakPolarHBondContact O-CG 3.33Å; P109-H112 WeakPolarHBondContact O-CB 3.33Å; P109-H112 PolarHBondContact O-N 3.26Å; P109-C113 PolarHBondContact O-N 2.96Å; P109-Q343 VanDerWaalsContact CB-OE1 3.27Å; P109-L368 HydrophobicContact CB-CD1 3.96Å; P109-L368 HydrophobicContact CG-CD1 3.71Å
110	Q	89.6	Confident	90.5	Very high	28 Å²	28	31.4 Å²	31.4	13%	0.131	14%	0.136	C	C	.	.	H	α-helix	trans	-62.6	-46.1	176.6	-176.1	69	22.1	0	0	112	L107 A108 C113 E114 M232 W237	L107-Q110 PolarHBondContact O-N 3.41Å; A108-Q110 VanDerWaalsContact C-N 3.32Å; A108-Q110 PolarHBondContact O-N 3.21Å; Q110-C113 WeakPolarHBondContact O-CB 3.44Å; Q110-C113 PolarHBondContact O-N 3.07Å; Q110-E114 PolarHBondContact O-N 3.46Å; Q110-M232 HydrophobicContact CB-CE 4.13Å; Q110-M232 HydrophobicContact CG-CE 3.86Å; Q110-W237 HydrophobicContact CG-CB 4.06Å; Q110-W237 HydrophobicContact CG-CG 4.18Å
111	L	90.4	Very high	90.4	Very high	0 Å²	0	33.1 Å²	33.1	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-75.8	-29.9	-178.4	-67.5	176.8	0	0	0	112.6	L107 A108 C113 W115 L117 L125 I176 W237	L107-L111 HydrophobicContact CD1-CD1 3.81Å; L107-L111 HydrophobicContact CD1-CD2 4.47Å; L107-L111 HydrophobicContact CD1-CG 3.95Å; L107-L111 HydrophobicContact CD2-CD1 4.12Å; L107-L111 HydrophobicContact CG-CD1 3.62Å; L107-L111 HydrophobicContact CG-CG 4.12Å; L107-L111 WeakPolarHBondContact O-CG 3.29Å; L107-L111 PolarHBondContact O-N 3.09Å; A108-L111 PolarHBondContact O-N 3.41Å; L111-C113 PolarHBondContact O-N 3.07Å; L111-W115 HydrophobicContact CB-CE3 4.44Å; L111-W115 HydrophobicContact CD1-CZ3 4.24Å; L111-W115 HydrophobicContact CD2-CD2 4.5Å; L111-W115 HydrophobicContact CD2-CE3 4.1Å; L111-W115 HydrophobicContact CD2-CH2 4.06Å; L111-W115 HydrophobicContact CD2-CZ2 4.46Å; L111-W115 HydrophobicContact CD2-CZ3 3.86Å; L111-W115 HydrophobicContact CG-CZ3 4.49Å; L111-W115 PolarHBondContact O-N 3.04Å; L111-W115 VanDerWaalsContact O-N 3.1Å; L111-L117 HydrophobicContact CB-CD1 4.28Å; L111-L125 HydrophobicContact CD1-CD2 3.57Å; L111-I176 HydrophobicContact CD1-CD1 3.67Å; L111-W237 HydrophobicContact CD2-CD2 4.04Å; L111-W237 HydrophobicContact CD2-CE3 4.42Å; L111-W237 HydrophobicContact CD2-CH2 4.27Å; L111-W237 HydrophobicContact CD2-CZ2 3.85Å
112	H	87.9	Confident	90.4	Very high	21 Å²	21	32.8 Å²	32.8	10%	0.097	14%	0.143	C	C	.	.	H	α-helix	trans	-51.2	-45.8	167.7	174.8	-99.6	0	0	0	110.2	A108 P109 R116 L117 V122	A108-H112 WeakPolarHBondContact O-CB 3.49Å; A108-H112 PolarHBondContact O-N 2.75Å; P109-H112 WeakPolarHBondContact O-CB 3.33Å; P109-H112 PolarHBondContact O-N 3.26Å; H112-R116 CarbonylContact O-C 3.31Å; H112-R116 WeakPolarHBondContact O-CA 3.3Å; H112-R116 PolarHBondContact O-N 3.39Å; H112-L117 PolarHBondContact CD2-O 2.89Å; H112-L117 PolarHBondContact NE2-O 2.92Å; H112-L117 PolarHBondContact O-N 3Å; H112-L117 VanDerWaalsContact O-N 3.16Å; H112-V122 HydrophobicContact CB-CG2 3.79Å
113	C	86.8	Confident	90.3	Very high	7 Å²	7	32.7 Å²	32.7	5%	0.047	14%	0.142	C	C	.	.	H	α-helix	trans	-72.7	-50.9	179.3	-90.2	0	0	0	0	115.2	P109 Q110 L111 W115 C365 Y367	P109-C113 PolarHBondContact O-N 2.96Å; Q110-C113 WeakPolarHBondContact O-CB 3.44Å; Q110-C113 PolarHBondContact O-N 3.07Å; L111-C113 PolarHBondContact O-N 3.07Å; C113-W115 VanDerWaalsContact C-N 3.31Å; C113-W115 PolarHBondContact O-N 3.17Å; C113-C365 WeakPolarHBondContact CA-SG 3.45Å; C113-C365 HydrophobicContact CB-CB 4.15Å; C113-C365 WeakPolarHBondContact CB-SG 3.49Å; C113-C365 WeakPolarHBondContact SG-CA 3.43Å; C113-C365 WeakPolarHBondContact SG-CB 3.28Å; C113-C365 CovalentContact SG-SG 2.03Å; C113-C365 PolarHBondContact SG-SG 2.83Å; C113-Y367 HydrophobicContact CB-CD1 3.99Å; C113-Y367 HydrophobicContact CB-CE1 3.35Å; C113-Y367 HydrophobicContact CB-CE2 4.4Å
114	E	89	Confident	90.3	Very high	86 Å²	86	35.5 Å²	35.5	40%	0.402	16%	0.157	S	C	.	.	H	α-helix	trans	-58.8	-42.8	-176.6	-177.3	74.2	-175.6	0	0	111.8	Q110	Q110-E114 PolarHBondContact O-N 3.46Å
115	W	89.7	Confident	90.4	Very high	60 Å²	60	35.4 Å²	35.4	23%	0.227	16%	0.157	C	C	.	.	H	α-helix	trans	-109.7	3.6	-174.2	-65.5	-26.2	0	0	0	114.2	L111 C113 L117 Y173 I176 W237	L111-W115 HydrophobicContact CB-CE3 4.44Å; L111-W115 HydrophobicContact CD1-CZ3 4.24Å; L111-W115 HydrophobicContact CD2-CD2 4.5Å; L111-W115 HydrophobicContact CD2-CE3 4.1Å; L111-W115 HydrophobicContact CD2-CH2 4.06Å; L111-W115 HydrophobicContact CD2-CZ2 4.46Å; L111-W115 HydrophobicContact CD2-CZ3 3.86Å; L111-W115 HydrophobicContact CG-CZ3 4.49Å; L111-W115 PolarHBondContact O-N 3.04Å; L111-W115 VanDerWaalsContact O-N 3.1Å; C113-W115 VanDerWaalsContact C-N 3.31Å; C113-W115 PolarHBondContact O-N 3.17Å; W115-L117 VanDerWaalsContact C-N 3.25Å; W115-L117 HydrophobicContact CB-CD2 3.74Å; W115-L117 HydrophobicContact CB-CG 3.88Å; W115-L117 HydrophobicContact CE3-CD1 4.28Å; W115-L117 PolarHBondContact O-N 2.92Å; W115-Y173 HydrophobicContact CE3-CD2 4.49Å; W115-I176 HydrophobicContact CH2-CB 4.37Å; W115-I176 HydrophobicContact CH2-CG2 4Å; W115-I176 HydrophobicContact CZ3-CB 4.46Å; W115-I176 HydrophobicContact CZ3-CG2 3.61Å; W115-W237 HydrophobicContact CH2-CH2 4.33Å; W115-W237 HydrophobicContact CH2-CZ2 4.44Å; W115-W237 HydrophobicContact CZ2-CH2 4.45Å; W115-W237 HydrophobicContact CZ2-CZ2 4.22Å
116	R	88.3	Confident	90.4	Very high	224 Å²	224	35.4 Å²	35.4	85%	0.845	16%	0.157	S	C	*	.	T	Hydrogen-bonded Turn	trans	50.7	47	-178.5	-58.3	-179.6	-176.3	172.6	0.6	111.9	H112	H112-R116 CarbonylContact O-C 3.31Å; H112-R116 WeakPolarHBondContact O-CA 3.3Å; H112-R116 PolarHBondContact O-N 3.39Å
117	L	88.1	Confident	90.6	Very high	9 Å²	9	35.6 Å²	35.6	5%	0.047	16%	0.158	C	C	.	.			trans	-72.7	142.2	-177.3	-55.8	174.5	0	0	0	109.5	L111 H112 W115 Q121 V122 Y173	L111-L117 HydrophobicContact CB-CD1 4.28Å; H112-L117 PolarHBondContact CD2-O 2.89Å; H112-L117 PolarHBondContact NE2-O 2.92Å; H112-L117 PolarHBondContact O-N 3Å; H112-L117 VanDerWaalsContact O-N 3.16Å; W115-L117 VanDerWaalsContact C-N 3.25Å; W115-L117 HydrophobicContact CB-CD2 3.74Å; W115-L117 HydrophobicContact CB-CG 3.88Å; W115-L117 HydrophobicContact CE3-CD1 4.28Å; W115-L117 PolarHBondContact O-N 2.92Å; L117-Q121 HydrophobicContact CB-CB 4.17Å; L117-Q121 VanDerWaalsContact CD2-OE1 3.25Å; L117-V122 HydrophobicContact CB-CG2 4.06Å; L117-Y173 HydrophobicContact CD1-CD2 3.59Å; L117-Y173 HydrophobicContact CD1-CE2 3.89Å; L117-Y173 HydrophobicContact CD2-CD2 3.79Å; L117-Y173 HydrophobicContact CD2-CE2 4.46Å; L117-Y173 HydrophobicContact CD2-CG 3.97Å; L117-Y173 HydrophobicContact CG-CD2 4.36Å
118	P	89.3	Confident	90.7	Very high	52 Å²	52	37 Å²	37	34%	0.338	17%	0.166	S	C	.	.			trans	-67.8	150.7	164.9	30.9	-35.6	0	0	0	110.3	W120 Q121 V122	P118-W120 HydrophobicContact CG-CD2 4.34Å; P118-W120 HydrophobicContact CG-CG 4.42Å; P118-W120 HydrophobicContact CG-CZ2 4.05Å; P118-W120 PolarHBondContact O-N 3.37Å; P118-W120 VanDerWaalsContact O-N 3.1Å; P118-Q121 HydrophobicContact CG-CB 4.12Å; P118-Q121 HydrophobicContact CG-CG 3.78Å; P118-Q121 WeakPolarHBondContact O-CA 2.99Å; P118-Q121 WeakPolarHBondContact O-CB 2.98Å; P118-Q121 PolarHBondContact O-N 2.94Å; P118-V122 PolarHBondContact O-N 3.07Å
119	S	86.5	Confident	91	Very high	10 Å²	10	37.1 Å²	37.1	7%	0.07	17%	0.167	C	C	.	.	H	α-helix	trans	-54.4	-32.3	-178.4	43.6	0	0	0	0	115.2	Q121 V122 A123 Q480 E484	S119-Q121 VanDerWaalsContact C-N 3.26Å; S119-Q121 PolarHBondContact O-N 3.44Å; S119-V122 WeakPolarHBondContact O-CB 3.27Å; S119-V122 PolarHBondContact O-N 3.05Å; S119-V122 VanDerWaalsContact O-N 3.15Å; S119-A123 WeakPolarHBondContact O-CB 3.42Å; S119-A123 PolarHBondContact O-N 2.96Å; S119-Q480 WeakPolarHBondContact CB-O 3.43Å; S119-E484 WeakPolarHBondContact CB-OE1 3.47Å; S119-E484 VanDerWaalsContact CB-OE2 3.29Å; S119-E484 WeakPolarHBondContact CB-OE2 3.06Å; S119-E484 PolarHBondContact OG-OE1 2.98Å; S119-E484 PolarHBondContact OG-OE2 3.3Å
120	W	90.1	Very high	91.4	Very high	134 Å²	134	37.2 Å²	37.2	51%	0.508	17%	0.167	S	C	.	.	H	α-helix	trans	-65	-29.3	174.9	68.7	-96	0	0	0	112.9	P118 L124 V481	P118-W120 HydrophobicContact CG-CD2 4.34Å; P118-W120 HydrophobicContact CG-CG 4.42Å; P118-W120 HydrophobicContact CG-CZ2 4.05Å; P118-W120 PolarHBondContact O-N 3.37Å; P118-W120 VanDerWaalsContact O-N 3.1Å; W120-L124 VanDerWaalsContact O-CB 3.27Å; W120-L124 WeakPolarHBondContact O-CB 3.32Å; W120-L124 PolarHBondContact O-N 3.43Å; W120-V481 HydrophobicContact CB-CG2 4.28Å
121	Q	93.8	Very high	91.6	Very high	42 Å²	42	39 Å²	39	20%	0.196	18%	0.18	C	C	.	.	H	α-helix	trans	-74.8	-35	172.9	-76.1	-178.7	5.7	0	0	111.4	L117 P118 S119 L124 L125 Y173	L117-Q121 HydrophobicContact CB-CB 4.17Å; L117-Q121 VanDerWaalsContact CD2-OE1 3.25Å; P118-Q121 HydrophobicContact CG-CB 4.12Å; P118-Q121 HydrophobicContact CG-CG 3.78Å; P118-Q121 WeakPolarHBondContact O-CA 2.99Å; P118-Q121 WeakPolarHBondContact O-CB 2.98Å; P118-Q121 PolarHBondContact O-N 2.94Å; S119-Q121 VanDerWaalsContact C-N 3.26Å; S119-Q121 PolarHBondContact O-N 3.44Å; Q121-L124 PolarHBondContact O-N 3.31Å; Q121-L125 PolarHBondContact O-N 3.44Å; Q121-Y173 WeakPolarHBondContact CA-OH 3.45Å; Q121-Y173 HydrophobicContact CB-CE1 4.22Å; Q121-Y173 HydrophobicContact CB-CE2 3.98Å; Q121-Y173 WeakPolarHBondContact CB-OH 3.39Å; Q121-Y173 HydrophobicContact CG-CE1 4.07Å; Q121-Y173 WeakPolarHBondContact O-CE2 3.28Å; Q121-Y173 PolarHBondContact O-OH 2.83Å
122	V	91.4	Very high	91.8	Very high	3 Å²	3	39.3 Å²	39.3	2%	0.018	18%	0.183	C	C	.	.	H	α-helix	trans	-65.1	-46.9	173.9	-175.2	0	0	0	0	110.4	A108 H112 L117 P118 S119 L124 L125 T126	A108-V122 HydrophobicContact CB-CG1 3.57Å; H112-V122 HydrophobicContact CB-CG2 3.79Å; L117-V122 HydrophobicContact CB-CG2 4.06Å; P118-V122 PolarHBondContact O-N 3.07Å; S119-V122 WeakPolarHBondContact O-CB 3.27Å; S119-V122 PolarHBondContact O-N 3.05Å; S119-V122 VanDerWaalsContact O-N 3.15Å; V122-L124 VanDerWaalsContact C-N 3.32Å; V122-L124 PolarHBondContact O-N 3.48Å; V122-L125 WeakPolarHBondContact O-CB 3.24Å; V122-L125 PolarHBondContact O-N 2.47Å; V122-L125 VanDerWaalsContact O-N 3.17Å; V122-T126 PolarHBondContact O-N 2.97Å; V122-T126 PolarHBondContact O-OG1 3.07Å
123	A	93.5	Very high	92.1	Very high	0 Å²	0	38.5 Å²	38.5	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-60.6	-39.5	173.1	0	0	0	0	0	112.5	S119 L125 T126 S127 P476 F477 Q480 V481	S119-A123 WeakPolarHBondContact O-CB 3.42Å; S119-A123 PolarHBondContact O-N 2.96Å; A123-L125 VanDerWaalsContact C-N 3.3Å; A123-L125 PolarHBondContact O-N 3.33Å; A123-T126 PolarHBondContact O-N 3.33Å; A123-T126 PolarHBondContact O-OG1 3.26Å; A123-S127 VanDerWaalsContact O-CB 3.23Å; A123-S127 WeakPolarHBondContact O-CB 3.44Å; A123-S127 PolarHBondContact O-N 3.36Å; A123-S127 PolarHBondContact O-OG 2.91Å; A123-P476 HydrophobicContact CB-CB 4.36Å; A123-F477 HydrophobicContact CB-CD1 4.08Å; A123-F477 HydrophobicContact CB-CD2 4.5Å; A123-F477 HydrophobicContact CB-CE1 4.26Å; A123-F477 HydrophobicContact CB-CG 4.21Å; A123-Q480 VanDerWaalsContact CA-OE1 3.28Å; A123-Q480 HydrophobicContact CB-CB 4.33Å; A123-V481 HydrophobicContact CB-CG2 3.66Å
124	L	95.3	Very high	92.3	Very high	61 Å²	61	41.7 Å²	41.7	32%	0.319	19%	0.194	S	C	.	.	H	α-helix	trans	-65.2	-34.8	176.9	-172.6	65.6	0	0	0	112.2	W120 Q121 V122 T126 V128 L177	W120-L124 VanDerWaalsContact O-CB 3.27Å; W120-L124 WeakPolarHBondContact O-CB 3.32Å; W120-L124 PolarHBondContact O-N 3.43Å; Q121-L124 PolarHBondContact O-N 3.31Å; V122-L124 VanDerWaalsContact C-N 3.32Å; V122-L124 PolarHBondContact O-N 3.48Å; L124-T126 VanDerWaalsContact C-N 3.32Å; L124-T126 PolarHBondContact O-N 3.28Å; L124-V128 WeakPolarHBondContact O-CB 3.43Å; L124-V128 PolarHBondContact O-N 3.08Å; L124-L177 HydrophobicContact CD2-CD1 4.37Å; L124-L177 HydrophobicContact CD2-CD2 3.93Å; L124-L177 HydrophobicContact CG-CD1 3.97Å; L124-L177 HydrophobicContact CG-CD2 4.4Å
125	L	93.9	Very high	92.4	Very high	2 Å²	2	40.3 Å²	40.3	1%	0.01	19%	0.194	C	C	.	.	H	α-helix	trans	-62.9	-37.7	178	-178.7	66.8	0	0	0	112.6	L111 Q121 V122 A123 V128 Y173 I176 L177 R180	L111-L125 HydrophobicContact CD1-CD2 3.57Å; Q121-L125 PolarHBondContact O-N 3.44Å; V122-L125 WeakPolarHBondContact O-CB 3.24Å; V122-L125 PolarHBondContact O-N 2.47Å; V122-L125 VanDerWaalsContact O-N 3.17Å; A123-L125 VanDerWaalsContact C-N 3.3Å; A123-L125 PolarHBondContact O-N 3.33Å; L125-V128 WeakPolarHBondContact O-CG1 3.29Å; L125-Y173 HydrophobicContact CB-CE2 4.43Å; L125-I176 HydrophobicContact CD1-CG2 3.83Å; L125-L177 HydrophobicContact CD1-CD1 4.43Å; L125-R180 HydrophobicContact CD1-CB 4.3Å; L125-R180 HydrophobicContact CD1-CG 3.93Å
126	T	93.5	Very high	92.6	Very high	0 Å²	0	37.4 Å²	37.4	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-84	-41.6	178.4	52.1	0	0	0	0	110.9	L104 A108 V122 A123 L124 V128 V129 F130 L336 P476 Q480	L104-T126 HydrophobicContact CB-CG2 4.05Å; L104-T126 HydrophobicContact CD2-CG2 4.48Å; A108-T126 HydrophobicContact CB-CG2 4.09Å; V122-T126 PolarHBondContact O-N 2.97Å; V122-T126 PolarHBondContact O-OG1 3.07Å; A123-T126 PolarHBondContact O-N 3.33Å; A123-T126 PolarHBondContact O-OG1 3.26Å; L124-T126 VanDerWaalsContact C-N 3.32Å; L124-T126 PolarHBondContact O-N 3.28Å; T126-V128 PolarHBondContact O-N 3.05Å; T126-V129 PolarHBondContact O-N 3.43Å; T126-F130 WeakPolarHBondContact O-CD2 3.45Å; T126-L336 HydrophobicContact CG2-CD2 4.22Å; T126-P476 WeakPolarHBondContact OG1-CB 3.36Å; T126-P476 WeakPolarHBondContact OG1-CG 3.16Å; T126-Q480 PolarHBondContact OG1-OE1 2.95Å
127	S	95.2	Very high	92.6	Very high	3 Å²	3	29.3 Å²	29.3	2%	0.021	16%	0.161	C	C	.	.	H	α-helix	trans	-61	-37.3	176.8	-74.2	0	0	0	0	113.3	A123 V129 F130 V131 L473 P476 F477	A123-S127 VanDerWaalsContact O-CB 3.23Å; A123-S127 WeakPolarHBondContact O-CB 3.44Å; A123-S127 PolarHBondContact O-N 3.36Å; A123-S127 PolarHBondContact O-OG 2.91Å; S127-V129 PolarHBondContact O-N 2.95Å; S127-F130 WeakPolarHBondContact O-CB 3.35Å; S127-F130 PolarHBondContact O-N 2.68Å; S127-V131 WeakPolarHBondContact O-CG2 3.49Å; S127-V131 PolarHBondContact O-N 3.29Å; S127-L473 WeakPolarHBondContact O-CD1 3.22Å; S127-L473 PolarHBondContact OG-O 3.19Å; S127-P476 WeakPolarHBondContact OG-CG 3.29Å; S127-F477 WeakPolarHBondContact OG-CE2 3.26Å
128	V	96.2	Very high	92.6	Very high	32 Å²	32	33.8 Å²	33.8	19%	0.194	19%	0.189	C	C	.	.	H	α-helix	trans	-62.2	-29.9	-178.5	78.4	0	0	0	0	112.5	L124 L125 T126 V131 G132 L177 R180	L124-V128 WeakPolarHBondContact O-CB 3.43Å; L124-V128 PolarHBondContact O-N 3.08Å; L125-V128 WeakPolarHBondContact O-CG1 3.29Å; T126-V128 PolarHBondContact O-N 3.05Å; V128-V131 PolarHBondContact O-N 3.45Å; V128-G132 PolarHBondContact O-N 2.9Å; V128-L177 HydrophobicContact CB-CD1 4.07Å; V128-L177 HydrophobicContact CG1-CD1 3.78Å; V128-L177 WeakPolarHBondContact CG1-O 3.4Å; V128-R180 HydrophobicContact CG1-CB 4.16Å
129	V	95.8	Very high	92.7	Very high	3 Å²	3	35.4 Å²	35.4	2%	0.018	19%	0.194	C	C	.	.	H	α-helix	trans	-64.3	-45.4	174.7	-177.3	0	0	0	0	109.9	L104 T126 S127 V131 G132 M133 R180 G184 I187	L104-V129 HydrophobicContact CD1-CB 4.02Å; L104-V129 HydrophobicContact CD1-CG1 4.17Å; L104-V129 HydrophobicContact CD1-CG2 3.92Å; L104-V129 HydrophobicContact CD2-CG2 3.92Å; T126-V129 PolarHBondContact O-N 3.43Å; S127-V129 PolarHBondContact O-N 2.95Å; V129-V131 PolarHBondContact O-N 2.72Å; V129-G132 PolarHBondContact O-N 2.85Å; V129-M133 WeakPolarHBondContact O-CB 3.41Å; V129-M133 PolarHBondContact O-N 2.87Å; V129-R180 HydrophobicContact CG2-CB 3.93Å; V129-G184 WeakPolarHBondContact O-CA 3.41Å; V129-I187 HydrophobicContact CG1-CD1 4.33Å
130	F	94.6	Very high	93	Very high	4 Å²	4	35.4 Å²	35.4	2%	0.018	19%	0.193	C	C	.	.	H	α-helix	trans	-66.1	-36.1	175.7	-64.8	-65.3	0	0	0	112.9	M101 T126 S127 M133 M134 Y332 A472 L473 P476	M101-F130 HydrophobicContact CE-CD1 4.21Å; M101-F130 HydrophobicContact CE-CE1 3.16Å; M101-F130 HydrophobicContact CE-CE2 4.11Å; M101-F130 HydrophobicContact CE-CZ 3.13Å; M101-F130 HydrophobicContact SD-CE1 4.13Å; T126-F130 WeakPolarHBondContact O-CD2 3.45Å; S127-F130 WeakPolarHBondContact O-CB 3.35Å; S127-F130 PolarHBondContact O-N 2.68Å; F130-M133 PolarHBondContact O-N 3.22Å; F130-M134 WeakPolarHBondContact O-CB 3.49Å; F130-M134 PolarHBondContact O-N 3.01Å; F130-Y332 HydrophobicContact CE1-CD1 4.33Å; F130-Y332 HydrophobicContact CE1-CD2 4.14Å; F130-Y332 HydrophobicContact CE1-CE1 4.4Å; F130-Y332 HydrophobicContact CE1-CE2 4.23Å; F130-Y332 HydrophobicContact CE1-CG 4.21Å; F130-Y332 HydrophobicContact CZ-CD1 4.06Å; F130-Y332 HydrophobicContact CZ-CD2 4.2Å; F130-Y332 AromaticContact CZ-CG 3.88Å; F130-Y332 HydrophobicContact CZ-CG 3.88Å; F130-A472 HydrophobicContact CD1-CB 3.5Å; F130-A472 VanDerWaalsContact CD1-CB 3.5Å; F130-A472 HydrophobicContact CD2-CB 4.44Å; F130-A472 WeakPolarHBondContact CD2-O 3.4Å; F130-A472 HydrophobicContact CE1-CB 3.4Å; F130-A472 VanDerWaalsContact CE1-CB 3.4Å; F130-A472 HydrophobicContact CE2-CB 4.36Å; F130-A472 WeakPolarHBondContact CE2-O 3.36Å; F130-A472 HydrophobicContact CG-CB 4.02Å; F130-A472 HydrophobicContact CZ-CB 3.84Å; F130-L473 HydrophobicContact CB-CB 4.28Å; F130-L473 HydrophobicContact CB-CD1 4.21Å; F130-P476 HydrophobicContact CD2-CG 4.34Å; F130-P476 HydrophobicContact CE2-CG 4.16Å
131	V	95.1	Very high	92.8	Very high	65 Å²	65	29.9 Å²	29.9	39%	0.394	18%	0.178	S	C	.	.	H	α-helix	trans	-61.5	-47.4	171.8	177.7	0	0	0	0	110.7	S127 V128 V129 M133 M134 S135 L473	S127-V131 WeakPolarHBondContact O-CG2 3.49Å; S127-V131 PolarHBondContact O-N 3.29Å; V128-V131 PolarHBondContact O-N 3.45Å; V129-V131 PolarHBondContact O-N 2.72Å; V131-M133 VanDerWaalsContact C-N 3.31Å; V131-M133 PolarHBondContact O-N 3.44Å; V131-M134 PolarHBondContact O-N 2.99Å; V131-S135 WeakPolarHBondContact O-CB 3.44Å; V131-S135 PolarHBondContact O-N 3.01Å; V131-S135 PolarHBondContact O-OG 3.44Å; V131-L473 HydrophobicContact CG2-CD1 3.31Å; V131-L473 HydrophobicContact CG2-CD2 4.28Å; V131-L473 HydrophobicContact CG2-CG 4.44Å
132	G	94.8	Very high	92.5	Very high	7 Å²	7	32 Å²	32	7%	0.072	19%	0.191	C	C	.	.	H	α-helix	trans	-57.8	-45.2	175.9	0	0	0	0	0	111.5	V128 V129 S135 S136 G184 F185	V128-G132 PolarHBondContact O-N 2.9Å; V129-G132 PolarHBondContact O-N 2.85Å; G132-S135 PolarHBondContact O-OG 3.41Å; G132-S135 VanDerWaalsContact O-OG 3.05Å; G132-S136 WeakPolarHBondContact O-CB 3Å; G132-S136 PolarHBondContact O-N 3.32Å; G132-S136 PolarHBondContact O-OG 3.01Å; G132-G184 VanDerWaalsContact C-C 3.5Å; G132-G184 CarbonylContact C-O 3.57Å; G132-F185 WeakPolarHBondContact O-CA 3.42Å
133	M	93.2	Very high	92.5	Very high	5 Å²	5	34.3 Å²	34.3	3%	0.025	20%	0.202	C	C	.	.	H	α-helix	trans	-65.4	-43.1	179.5	-168.2	176.1	-165.3	0	0	112.9	V129 F130 V131 S136 S137 G184 I187 R469	V129-M133 WeakPolarHBondContact O-CB 3.41Å; V129-M133 PolarHBondContact O-N 2.87Å; F130-M133 PolarHBondContact O-N 3.22Å; V131-M133 VanDerWaalsContact C-N 3.31Å; V131-M133 PolarHBondContact O-N 3.44Å; M133-S136 PolarHBondContact O-OG 3.18Å; M133-S136 VanDerWaalsContact O-OG 3.13Å; M133-S137 PolarHBondContact O-N 3.04Å; M133-S137 VanDerWaalsContact O-N 3.16Å; M133-G184 WeakPolarHBondContact CA-O 3.41Å; M133-G184 PolarHBondContact N-O 2.74Å; M133-G184 VanDerWaalsContact N-O 3.16Å; M133-I187 HydrophobicContact CE-CG2 3.59Å; M133-I187 HydrophobicContact CG-CG2 4.25Å; M133-I187 HydrophobicContact SD-CG2 3.77Å; M133-R469 PolarHBondContact SD-NH1 3.22Å
134	M	91.3	Very high	92.2	Very high	73 Å²	73	34.3 Å²	34.3	36%	0.36	20%	0.202	S	C	.	.	H	α-helix	trans	-65.7	-47.5	179.4	-173.4	174.5	70	0	0	111.3	F130 V131 S136 S137 R469 V470 L473	F130-M134 WeakPolarHBondContact O-CB 3.49Å; F130-M134 PolarHBondContact O-N 3.01Å; V131-M134 PolarHBondContact O-N 2.99Å; M134-S136 VanDerWaalsContact C-N 3.32Å; M134-S136 PolarHBondContact O-N 2.72Å; M134-S137 PolarHBondContact O-OG 2.77Å; M134-R469 HydrophobicContact CB-CB 4.35Å; M134-R469 HydrophobicContact CG-CB 4.42Å; M134-V470 HydrophobicContact SD-CG2 4.24Å; M134-L473 HydrophobicContact CE-CD2 4.47Å
135	S	91.8	Very high	91.8	Very high	57 Å²	57	34.2 Å²	34.2	40%	0.399	20%	0.202	S	C	.	.	H	α-helix	trans	-66.8	-31.4	-178.8	56.3	0	0	0	0	113.5	V131 G132	V131-S135 WeakPolarHBondContact O-CB 3.44Å; V131-S135 PolarHBondContact O-N 3.01Å; V131-S135 PolarHBondContact O-OG 3.44Å; G132-S135 PolarHBondContact O-OG 3.41Å; G132-S135 VanDerWaalsContact O-OG 3.05Å
136	S	93.7	Very high	91.4	Very high	0 Å²	0	39.2 Å²	39.2	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-86.8	-24.2	-177.4	62.5	0	0	0	0	114.6	G132 M133 M134 T138 L139 W140 F185 G188	G132-S136 WeakPolarHBondContact O-CB 3Å; G132-S136 PolarHBondContact O-N 3.32Å; G132-S136 PolarHBondContact O-OG 3.01Å; M133-S136 PolarHBondContact O-OG 3.18Å; M133-S136 VanDerWaalsContact O-OG 3.13Å; M134-S136 VanDerWaalsContact C-N 3.32Å; M134-S136 PolarHBondContact O-N 2.72Å; S136-T138 VanDerWaalsContact C-N 3.3Å; S136-T138 PolarHBondContact O-N 2.71Å; S136-L139 WeakPolarHBondContact O-CB 3.48Å; S136-L139 PolarHBondContact O-N 3.32Å; S136-W140 PolarHBondContact O-N 3.43Å; S136-F185 WeakPolarHBondContact CB-O 3.26Å; S136-F185 PolarHBondContact OG-O 3.13Å; S136-G188 WeakPolarHBondContact OG-CA 3.37Å
137	S	87.7	Confident	91.2	Very high	54 Å²	54	46.1 Å²	46.1	38%	0.378	25%	0.252	S	S	.	.	H	α-helix	trans	-54.2	-41.8	-175.1	63.3	0	0	0	0	113.9	M133 M134 G141	M133-S137 PolarHBondContact O-N 3.04Å; M133-S137 VanDerWaalsContact O-N 3.16Å; M134-S137 PolarHBondContact O-OG 2.77Å; S137-G141 PolarHBondContact O-N 3.22Å
138	T	87.6	Confident	90.9	Very high	103 Å²	103	46 Å²	46	63%	0.632	25%	0.251	S	S	*	.	H	α-helix	trans	-71.4	-37.9	177.1	51.4	0	0	0	0	112.1	S136 G141 N142	S136-T138 VanDerWaalsContact C-N 3.3Å; S136-T138 PolarHBondContact O-N 2.71Å; T138-G141 PolarHBondContact O-N 3.14Å; T138-N142 PolarHBondContact O-N 3Å
139	L	91.9	Very high	90.6	Very high	86 Å²	86	46 Å²	46	45%	0.45	25%	0.248	S	C	.	.	H	α-helix	trans	-65.3	-49.4	177.5	-65.8	173.3	0	0	0	110.9	S136 G141 N142 I143 F185	S136-L139 WeakPolarHBondContact O-CB 3.48Å; S136-L139 PolarHBondContact O-N 3.32Å; L139-G141 VanDerWaalsContact C-N 3.31Å; L139-G141 PolarHBondContact O-N 2.81Å; L139-N142 PolarHBondContact O-N 2.93Å; L139-I143 VanDerWaalsContact O-CG1 3.29Å; L139-I143 WeakPolarHBondContact O-CG1 3.04Å; L139-I143 PolarHBondContact O-N 3.02Å; L139-F185 HydrophobicContact CD1-CE2 3.83Å; L139-F185 HydrophobicContact CD1-CZ 3.59Å
140	W	92.1	Very high	90.4	Very high	9 Å²	9	48.6 Å²	48.6	3%	0.034	26%	0.259	C	S	.	.	H	α-helix	trans	-65	-35.4	176.3	-66.6	120	0	0	0	112.5	S136 I143 S144 I155 F185 G189	S136-W140 PolarHBondContact O-N 3.43Å; W140-I143 HydrophobicContact CE3-CD1 3.89Å; W140-I143 HydrophobicContact CZ3-CD1 4.01Å; W140-I143 PolarHBondContact O-N 3.5Å; W140-S144 WeakPolarHBondContact O-CB 3.29Å; W140-S144 PolarHBondContact O-N 2.84Å; W140-I155 HydrophobicContact CH2-CB 4.41Å; W140-I155 HydrophobicContact CH2-CG2 3.73Å; W140-I155 HydrophobicContact CZ3-CB 4.02Å; W140-I155 HydrophobicContact CZ3-CG2 3.71Å; W140-F185 HydrophobicContact CZ2-CD1 4.04Å; W140-F185 AromaticContact CZ2-CE1 3.84Å; W140-F185 HydrophobicContact CZ2-CE1 3.84Å; W140-F185 PolarHBondContact NE1-O 2.9Å; W140-G189 VanDerWaalsContact CD1-CA 3.48Å; W140-G189 VanDerWaalsContact CG-CA 3.48Å
141	G	86.4	Confident	90.2	Very high	19 Å²	19	51 Å²	51	20%	0.196	27%	0.274	C	S	.	.	H	α-helix	trans	-58.6	-47.5	171.7	0	0	0	0	0	112.1	S137 T138 L139 S144 D145	S137-G141 PolarHBondContact O-N 3.22Å; T138-G141 PolarHBondContact O-N 3.14Å; L139-G141 VanDerWaalsContact C-N 3.31Å; L139-G141 PolarHBondContact O-N 2.81Å; G141-S144 PolarHBondContact O-N 3.1Å; G141-D145 WeakPolarHBondContact O-CB 3.43Å; G141-D145 PolarHBondContact O-N 3.41Å
142	N	87.6	Confident	90	Very high	87 Å²	87	47.9 Å²	47.9	47%	0.465	26%	0.255	S	S	.	.	H	α-helix	trans	-67.5	-42.4	178.2	-170	32	0	0	0	112.4	T138 L139 S144 D145 Q146	T138-N142 PolarHBondContact O-N 3Å; L139-N142 PolarHBondContact O-N 2.93Å; N142-S144 VanDerWaalsContact C-N 3.31Å; N142-S144 PolarHBondContact O-N 3.47Å; N142-D145 PolarHBondContact O-N 3.29Å; N142-Q146 WeakPolarHBondContact O-CB 3.32Å; N142-Q146 WeakPolarHBondContact O-CG 3.44Å; N142-Q146 PolarHBondContact O-N 3.34Å; N142-Q146 PolarHBondContact OD1-NE2 3.43Å; N142-Q146 VanDerWaalsContact OD1-NE2 3.16Å
143	I	91.2	Very high	89.9	Confident	50 Å²	50	47.6 Å²	47.6	26%	0.256	25%	0.252	S	S	.	.	H	α-helix	trans	-60.7	-43.6	175.7	-68.9	166.2	0	0	0	110.4	L139 W140 Q146 Y147	L139-I143 VanDerWaalsContact O-CG1 3.29Å; L139-I143 WeakPolarHBondContact O-CG1 3.04Å; L139-I143 PolarHBondContact O-N 3.02Å; W140-I143 HydrophobicContact CE3-CD1 3.89Å; W140-I143 HydrophobicContact CZ3-CD1 4.01Å; W140-I143 PolarHBondContact O-N 3.5Å; I143-Q146 PolarHBondContact O-N 3.2Å; I143-Y147 HydrophobicContact CG2-CD2 4.2Å; I143-Y147 WeakPolarHBondContact O-CB 3.48Å; I143-Y147 PolarHBondContact O-N 2.87Å
144	S	87.6	Confident	89.9	Confident	0 Å²	0	50.2 Å²	50.2	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-66.6	-37.7	179.4	-175.8	0	0	0	0	112.4	W140 G141 N142 G148 R149 Q192	W140-S144 WeakPolarHBondContact O-CB 3.29Å; W140-S144 PolarHBondContact O-N 2.84Å; G141-S144 PolarHBondContact O-N 3.1Å; N142-S144 VanDerWaalsContact C-N 3.31Å; N142-S144 PolarHBondContact O-N 3.47Å; S144-G148 CarbonylContact O-C 3.55Å; S144-G148 WeakPolarHBondContact O-CA 3.48Å; S144-G148 PolarHBondContact O-N 2.93Å; S144-R149 PolarHBondContact O-N 3.46Å; S144-R149 WeakPolarHBondContact OG-CA 3.43Å; S144-R149 VanDerWaalsContact OG-CD 3.29Å; S144-R149 WeakPolarHBondContact OG-CD 3.42Å; S144-R149 PolarHBondContact OG-NH1 2.87Å; S144-Q192 VanDerWaalsContact CB-OE1 3.32Å; S144-Q192 PolarHBondContact OG-OE1 3.38Å
145	D	86.3	Confident	90.1	Very high	60 Å²	60	50.4 Å²	50.4	32%	0.321	27%	0.265	S	S	.	.	H	α-helix	trans	-71.7	-33.8	174.9	-82	12.6	0	0	0	112.3	G141 N142 R149 Y264 R302	G141-D145 WeakPolarHBondContact O-CB 3.43Å; G141-D145 PolarHBondContact O-N 3.41Å; N142-D145 PolarHBondContact O-N 3.29Å; D145-R149 IonicContact OD1-CZ 3.25Å; D145-R149 IonicContact OD1-NH1 3.75Å; D145-R149 PolarHBondContact OD1-NH1 3.29Å; D145-R149 IonicContact OD1-NH2 3.29Å; D145-R149 PolarHBondContact OD1-NH2 3.47Å; D145-Y264 WeakPolarHBondContact O-CE2 2.94Å; D145-R302 IonicContact OD2-CZ 2.76Å; D145-R302 IonicContact OD2-NH1 3.24Å; D145-R302 PolarHBondContact OD2-NH1 2.96Å; D145-R302 IonicContact OD2-NH2 2.84Å
146	Q	87	Confident	90.2	Very high	107 Å²	107	47.7 Å²	47.7	50%	0.5	25%	0.246	S	C	.	.	H	α-helix	trans	-86.7	-47.8	-177.5	-71.4	-174.4	1	0	0	113.9	N142 I143 Y264	N142-Q146 WeakPolarHBondContact O-CB 3.32Å; N142-Q146 WeakPolarHBondContact O-CG 3.44Å; N142-Q146 PolarHBondContact O-N 3.34Å; N142-Q146 PolarHBondContact OD1-NE2 3.43Å; N142-Q146 VanDerWaalsContact OD1-NE2 3.16Å; I143-Q146 PolarHBondContact O-N 3.2Å; Q146-Y264 PolarHBondContact O-OH 2.79Å
147	Y	88.8	Confident	90.3	Very high	144 Å²	144	47.7 Å²	47.7	57%	0.565	25%	0.246	S	C	*	.	H	α-helix	trans	-105	1.9	-171.4	-62.4	-83.3	0	0	0	113.7	I143 T151 Y264	I143-Y147 HydrophobicContact CG2-CD2 4.2Å; I143-Y147 WeakPolarHBondContact O-CB 3.48Å; I143-Y147 PolarHBondContact O-N 2.87Å; Y147-T151 WeakPolarHBondContact O-CB 3.25Å; Y147-T151 PolarHBondContact O-OG1 3.37Å; Y147-Y264 VanDerWaalsContact C-OH 3.27Å
148	G	88.9	Confident	90.6	Very high	0 Å²	0	48.7 Å²	48.7	0%	0	25%	0.247	C	C	.	.			trans	98.4	152.4	-179.9	0	0	0	0	0	113.2	S144 T151 G152 E260 Y264	S144-G148 CarbonylContact O-C 3.55Å; S144-G148 WeakPolarHBondContact O-CA 3.48Å; S144-G148 PolarHBondContact O-N 2.93Å; G148-T151 PolarHBondContact O-N 3.03Å; G148-G152 PolarHBondContact O-N 3.38Å; G148-E260 WeakPolarHBondContact CA-OE2 3.1Å; G148-Y264 VanDerWaalsContact CA-CZ 3.45Å; G148-Y264 VanDerWaalsContact N-CZ 3.26Å; G148-Y264 PolarHBondContact N-OH 3.19Å
149	R	89.7	Confident	91	Very high	34 Å²	34	47.8 Å²	47.8	13%	0.128	23%	0.232	C	C	.	.	H	α-helix	trans	-70.8	-38.9	-172.8	-65.7	-101	-178.7	-104.6	-2	111.2	S144 D145 L153 Q192 L196 E199 E260	S144-R149 PolarHBondContact O-N 3.46Å; S144-R149 WeakPolarHBondContact OG-CA 3.43Å; S144-R149 VanDerWaalsContact OG-CD 3.29Å; S144-R149 WeakPolarHBondContact OG-CD 3.42Å; S144-R149 PolarHBondContact OG-NH1 2.87Å; D145-R149 IonicContact OD1-CZ 3.25Å; D145-R149 IonicContact OD1-NH1 3.75Å; D145-R149 PolarHBondContact OD1-NH1 3.29Å; D145-R149 IonicContact OD1-NH2 3.29Å; D145-R149 PolarHBondContact OD1-NH2 3.47Å; R149-L153 WeakPolarHBondContact O-CB 3.43Å; R149-L153 PolarHBondContact O-N 3.31Å; R149-L153 VanDerWaalsContact O-N 3.08Å; R149-Q192 VanDerWaalsContact NH1-OE1 3.17Å; R149-L196 HydrophobicContact CB-CB 4.45Å; R149-L196 HydrophobicContact CB-CD1 3.78Å; R149-E199 IonicContact NE-OE1 3.9Å; R149-E199 PolarHBondContact NE-OE1 3.4Å; R149-E260 PolarHBondContact N-OE1 3.15Å; R149-E260 PolarHBondContact N-OE2 3.22Å
150	K	90.9	Very high	91.2	Very high	56 Å²	56	43.8 Å²	43.8	24%	0.243	21%	0.211	C	C	.	.	H	α-helix	trans	-61.4	-47.2	173.6	176	-168.1	177.7	165.7	0	110.8	L153 K154 L258 E260	K150-L153 PolarHBondContact O-N 3.28Å; K150-K154 VanDerWaalsContact O-CB 3.32Å; K150-K154 WeakPolarHBondContact O-CB 3.42Å; K150-K154 PolarHBondContact O-N 3.09Å; K150-L258 HydrophobicContact CB-CD2 4.43Å; K150-L258 WeakPolarHBondContact CD-O 3.41Å; K150-L258 WeakPolarHBondContact CE-O 3.25Å; K150-L258 HydrophobicContact CG-CB 4.35Å; K150-L258 HydrophobicContact CG-CD2 4Å; K150-L258 HydrophobicContact CG-CG 4.18Å; K150-L258 PolarHBondContact NZ-O 3.29Å; K150-E260 VanDerWaalsContact CB-OE2 3.25Å; K150-E260 WeakPolarHBondContact CB-OE2 3.37Å; K150-E260 PolarHBondContact N-OE1 3.26Å; K150-E260 PolarHBondContact N-OE2 3.1Å
151	T	91	Very high	91.4	Very high	54 Å²	54	44.2 Å²	44.2	33%	0.331	21%	0.214	S	C	.	.	H	α-helix	trans	-62.7	-47.4	-178	-54.4	0	0	0	0	110.9	Y147 G148 L153 K154 I155	Y147-T151 WeakPolarHBondContact O-CB 3.25Å; Y147-T151 PolarHBondContact O-OG1 3.37Å; G148-T151 PolarHBondContact O-N 3.03Å; T151-L153 PolarHBondContact O-N 3.07Å; T151-K154 PolarHBondContact O-N 3.44Å; T151-I155 HydrophobicContact CG2-CD1 3.78Å; T151-I155 HydrophobicContact CG2-CG1 4.48Å; T151-I155 VanDerWaalsContact O-CG1 3.28Å; T151-I155 WeakPolarHBondContact O-CG1 3.45Å; T151-I155 PolarHBondContact O-N 2.82Å
152	G	91.7	Very high	91.9	Very high	1 Å²	1	50 Å²	50	1%	0.01	23%	0.231	C	C	.	.	H	α-helix	trans	-57.5	-48.7	176.4	0	0	0	0	0	112.7	G148 I155 S156	G148-G152 PolarHBondContact O-N 3.38Å; G152-I155 PolarHBondContact O-N 3.45Å; G152-S156 WeakPolarHBondContact O-CB 3.42Å; G152-S156 PolarHBondContact O-N 3.33Å; G152-S156 PolarHBondContact O-OG 3.04Å
153	L	92.3	Very high	92.4	Very high	0 Å²	0	48.1 Å²	48.1	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-65.1	-39.6	179.1	-178.8	62.1	0	0	0	112.8	A93 R149 K150 T151 S156 V157 L196 F251 L258	A93-L153 HydrophobicContact CB-CD1 4.5Å; R149-L153 WeakPolarHBondContact O-CB 3.43Å; R149-L153 PolarHBondContact O-N 3.31Å; R149-L153 VanDerWaalsContact O-N 3.08Å; K150-L153 PolarHBondContact O-N 3.28Å; T151-L153 PolarHBondContact O-N 3.07Å; L153-S156 WeakPolarHBondContact CA-OG 3.42Å; L153-S156 PolarHBondContact O-OG 3.48Å; L153-V157 HydrophobicContact CD1-CG2 4.11Å; L153-V157 WeakPolarHBondContact O-CB 3.37Å; L153-V157 WeakPolarHBondContact O-CG2 3.3Å; L153-V157 PolarHBondContact O-N 3Å; L153-L196 HydrophobicContact CD2-CD2 4.39Å; L153-F251 HydrophobicContact CD2-CE2 4.27Å; L153-F251 HydrophobicContact CD2-CZ 3.62Å; L153-F251 HydrophobicContact CG-CE1 4.26Å; L153-F251 HydrophobicContact CG-CZ 3.78Å; L153-L258 HydrophobicContact CD2-CD2 4.12Å
154	K	93.5	Very high	92.6	Very high	61 Å²	61	45.7 Å²	45.7	27%	0.265	21%	0.205	S	C	.	.	H	α-helix	trans	-64.4	-46.1	178.5	-179.4	176.2	178.2	178.5	0	111.4	K150 T151 L158	K150-K154 VanDerWaalsContact O-CB 3.32Å; K150-K154 WeakPolarHBondContact O-CB 3.42Å; K150-K154 PolarHBondContact O-N 3.09Å; T151-K154 PolarHBondContact O-N 3.44Å; K154-L158 HydrophobicContact CG-CD1 3.99Å; K154-L158 WeakPolarHBondContact O-CB 3.32Å; K154-L158 VanDerWaalsContact O-CG 3.27Å; K154-L158 WeakPolarHBondContact O-CG 3.24Å; K154-L158 PolarHBondContact O-N 2.84Å; K154-L158 VanDerWaalsContact O-N 3.07Å
155	I	94.6	Very high	93	Very high	76 Å²	76	48.6 Å²	48.6	39%	0.39	22%	0.22	S	C	.	.	H	α-helix	trans	-66.2	-42.9	-179.1	-62.9	169.2	0	0	0	110.1	W140 T151 G152 L158 W159	W140-I155 HydrophobicContact CH2-CB 4.41Å; W140-I155 HydrophobicContact CH2-CG2 3.73Å; W140-I155 HydrophobicContact CZ3-CB 4.02Å; W140-I155 HydrophobicContact CZ3-CG2 3.71Å; T151-I155 HydrophobicContact CG2-CD1 3.78Å; T151-I155 HydrophobicContact CG2-CG1 4.48Å; T151-I155 VanDerWaalsContact O-CG1 3.28Å; T151-I155 WeakPolarHBondContact O-CG1 3.45Å; T151-I155 PolarHBondContact O-N 2.82Å; G152-I155 PolarHBondContact O-N 3.45Å; I155-L158 PolarHBondContact O-N 3.01Å; I155-W159 VanDerWaalsContact O-CB 3.29Å; I155-W159 WeakPolarHBondContact O-CB 3.14Å; I155-W159 PolarHBondContact O-N 3.41Å
156	S	94.8	Very high	93.5	Very high	0 Å²	0	48 Å²	48	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-63.6	-44.1	179.7	66.5	0	0	0	0	112.4	G152 L153 W159 T160	G152-S156 WeakPolarHBondContact O-CB 3.42Å; G152-S156 PolarHBondContact O-N 3.33Å; G152-S156 PolarHBondContact O-OG 3.04Å; L153-S156 WeakPolarHBondContact CA-OG 3.42Å; L153-S156 PolarHBondContact O-OG 3.48Å; S156-W159 WeakPolarHBondContact O-CB 3.43Å; S156-W159 PolarHBondContact O-N 3.32Å; S156-T160 PolarHBondContact O-N 2.79Å; S156-T160 PolarHBondContact O-OG1 3.44Å
157	V	93.9	Very high	94	Very high	1 Å²	1	42.9 Å²	42.9	1%	0.006	19%	0.193	C	C	.	.	H	α-helix	trans	-65.8	-42.6	177.6	168.7	0	0	0	0	112.1	A93 L153 W159 T160 L161 L248 F251	A93-V157 HydrophobicContact CB-CG2 4.36Å; L153-V157 HydrophobicContact CD1-CG2 4.11Å; L153-V157 WeakPolarHBondContact O-CB 3.37Å; L153-V157 WeakPolarHBondContact O-CG2 3.3Å; L153-V157 PolarHBondContact O-N 3Å; V157-W159 VanDerWaalsContact C-N 3.29Å; V157-W159 PolarHBondContact O-N 2.72Å; V157-T160 PolarHBondContact O-N 3.13Å; V157-L161 VanDerWaalsContact O-CB 3.32Å; V157-L161 WeakPolarHBondContact O-CB 3.25Å; V157-L161 PolarHBondContact O-N 3Å; V157-L248 HydrophobicContact CG1-CB 4.32Å; V157-L248 HydrophobicContact CG1-CD2 3.76Å; V157-L248 HydrophobicContact CG2-CD2 4.5Å; V157-F251 HydrophobicContact CB-CD1 3.88Å; V157-F251 HydrophobicContact CB-CE1 4.03Å; V157-F251 HydrophobicContact CG1-CB 4.34Å; V157-F251 HydrophobicContact CG1-CD1 3.45Å; V157-F251 VanDerWaalsContact CG1-CD1 3.45Å; V157-F251 HydrophobicContact CG1-CE1 4.13Å; V157-F251 HydrophobicContact CG1-CG 4.18Å; V157-F251 HydrophobicContact CG2-CD1 3.88Å; V157-F251 HydrophobicContact CG2-CE1 3.82Å
158	L	95.3	Very high	94.3	Very high	75 Å²	75	36.1 Å²	36.1	39%	0.393	17%	0.166	S	C	.	.	H	α-helix	trans	-64.1	-36.5	176.3	-72.2	174	0	0	0	112.1	K154 I155 Y162 A252	K154-L158 HydrophobicContact CG-CD1 3.99Å; K154-L158 WeakPolarHBondContact O-CB 3.32Å; K154-L158 VanDerWaalsContact O-CG 3.27Å; K154-L158 WeakPolarHBondContact O-CG 3.24Å; K154-L158 PolarHBondContact O-N 2.84Å; K154-L158 VanDerWaalsContact O-N 3.07Å; I155-L158 PolarHBondContact O-N 3.01Å; L158-Y162 WeakPolarHBondContact O-CB 3.31Å; L158-Y162 PolarHBondContact O-N 3.37Å; L158-A252 HydrophobicContact CD2-CB 3.71Å
159	W	96.6	Very high	94.6	Very high	83 Å²	83	42.5 Å²	42.5	31%	0.314	19%	0.194	S	C	.	.	H	α-helix	trans	-62.3	-51.3	173.9	-175.3	-79.8	0	0	0	111.2	I155 S156 V157 L161 Y162 Y163 L182 F185	I155-W159 VanDerWaalsContact O-CB 3.29Å; I155-W159 WeakPolarHBondContact O-CB 3.14Å; I155-W159 PolarHBondContact O-N 3.41Å; S156-W159 WeakPolarHBondContact O-CB 3.43Å; S156-W159 PolarHBondContact O-N 3.32Å; V157-W159 VanDerWaalsContact C-N 3.29Å; V157-W159 PolarHBondContact O-N 2.72Å; W159-L161 VanDerWaalsContact C-N 3.34Å; W159-L161 PolarHBondContact O-N 3.07Å; W159-Y162 PolarHBondContact O-N 3.35Å; W159-Y163 AromaticContact CD1-CD2 3.64Å; W159-Y163 AromaticContact CD1-CE2 3.97Å; W159-Y163 AromaticContact CD2-CD2 3.99Å; W159-Y163 HydrophobicContact CD2-CD2 3.99Å; W159-Y163 AromaticContact CD2-CE2 3.53Å; W159-Y163 HydrophobicContact CD2-CE2 3.53Å; W159-Y163 AromaticContact CE2-CD2 3.69Å; W159-Y163 AromaticContact CE2-CE2 3.21Å; W159-Y163 AromaticContact CE3-CE2 3.98Å; W159-Y163 HydrophobicContact CE3-CE2 3.98Å; W159-Y163 AromaticContact CG-CD2 3.99Å; W159-Y163 HydrophobicContact CG-CD2 3.99Å; W159-Y163 HydrophobicContact CG-CE2 4.02Å; W159-Y163 AromaticContact CH2-CE2 3.91Å; W159-Y163 HydrophobicContact CH2-CE2 3.91Å; W159-Y163 HydrophobicContact CZ2-CD2 4.28Å; W159-Y163 AromaticContact CZ2-CE2 3.44Å; W159-Y163 HydrophobicContact CZ2-CE2 3.44Å; W159-Y163 VanDerWaalsContact CZ2-CE2 3.44Å; W159-Y163 HydrophobicContact CZ3-CE2 4.15Å; W159-Y163 AromaticContact NE1-CD2 3.44Å; W159-Y163 AromaticContact NE1-CE2 3.51Å; W159-Y163 VanDerWaalsContact O-CD2 3.26Å; W159-Y163 WeakPolarHBondContact O-CD2 3.26Å; W159-Y163 PolarHBondContact O-N 3.26Å; W159-Y163 VanDerWaalsContact O-N 3.13Å; W159-L182 VanDerWaalsContact CD1-O 3.29Å; W159-L182 HydrophobicContact CZ2-CD2 4.15Å; W159-L182 PolarHBondContact NE1-O 3.48Å; W159-F185 HydrophobicContact CZ2-CD1 4.45Å; W159-F185 AromaticContact NE1-CD1 3.95Å
160	T	96.1	Very high	94.9	Very high	2 Å²	2	40.9 Å²	40.9	1%	0.012	19%	0.188	C	C	.	.	H	α-helix	trans	-58.9	-45.1	176.9	-52.3	0	0	0	0	111.4	S156 V157 Y162 G164 V183 G186 I187 L248	S156-T160 PolarHBondContact O-N 2.79Å; S156-T160 PolarHBondContact O-OG1 3.44Å; V157-T160 PolarHBondContact O-N 3.13Å; T160-Y162 PolarHBondContact O-N 2.96Å; T160-G164 WeakPolarHBondContact O-CA 3.28Å; T160-G164 PolarHBondContact O-N 3.48Å; T160-V183 HydrophobicContact CG2-CG1 4.05Å; T160-G186 VanDerWaalsContact OG1-CA 3.25Å; T160-G186 WeakPolarHBondContact OG1-CA 3.35Å; T160-I187 HydrophobicContact CG2-CG1 3.92Å; T160-I187 PolarHBondContact OG1-N 2.88Å; T160-L248 HydrophobicContact CG2-CD1 3.72Å
161	L	96.4	Very high	95	Very high	18 Å²	18	42 Å²	42	9%	0.094	20%	0.202	C	C	.	.	H	α-helix	trans	-58.1	-48.1	178.4	176.3	60.5	0	0	0	112	V157 W159 I165 A245 L248 L249 A252	V157-L161 VanDerWaalsContact O-CB 3.32Å; V157-L161 WeakPolarHBondContact O-CB 3.25Å; V157-L161 PolarHBondContact O-N 3Å; W159-L161 VanDerWaalsContact C-N 3.34Å; W159-L161 PolarHBondContact O-N 3.07Å; L161-I165 HydrophobicContact CD1-CD1 3.64Å; L161-I165 HydrophobicContact CD1-CG1 4.29Å; L161-I165 HydrophobicContact CG-CD1 4.24Å; L161-I165 WeakPolarHBondContact O-CG1 3.33Å; L161-I165 PolarHBondContact O-N 3.26Å; L161-I165 VanDerWaalsContact O-N 3.09Å; L161-A245 HydrophobicContact CD1-CB 3.9Å; L161-L248 HydrophobicContact CB-CB 4.14Å; L161-L248 HydrophobicContact CD1-CB 4Å; L161-L249 HydrophobicContact CD1-CB 4.24Å; L161-L249 HydrophobicContact CD2-CB 4.48Å; L161-L249 HydrophobicContact CD2-CD1 4.13Å; L161-A252 HydrophobicContact CD2-CB 4.13Å
162	Y	96.9	Very high	95.2	Very high	142 Å²	142	43.1 Å²	43.1	56%	0.557	21%	0.208	S	C	*	.	H	α-helix	trans	-63.3	-52.6	-178	175.3	-103.3	0	0	0	112	L158 W159 T160 G164 L166	L158-Y162 WeakPolarHBondContact O-CB 3.31Å; L158-Y162 PolarHBondContact O-N 3.37Å; W159-Y162 PolarHBondContact O-N 3.35Å; T160-Y162 PolarHBondContact O-N 2.96Å; Y162-G164 VanDerWaalsContact C-N 3.32Å; Y162-G164 PolarHBondContact O-N 2.9Å; Y162-L166 HydrophobicContact CE1-CD2 4.11Å; Y162-L166 VanDerWaalsContact O-CB 3.28Å; Y162-L166 WeakPolarHBondContact O-CB 3.18Å; Y162-L166 PolarHBondContact O-N 3.24Å
163	Y	97.3	Very high	95.3	Very high	46 Å²	46	44.5 Å²	44.5	18%	0.18	21%	0.213	C	C	.	.	H	α-helix	trans	-73.1	-26.5	-179.4	-68	-68	0	0	0	112.8	W159 L166 S167 L179 L182 V183	W159-Y163 AromaticContact CD1-CD2 3.64Å; W159-Y163 AromaticContact CD1-CE2 3.97Å; W159-Y163 AromaticContact CD2-CD2 3.99Å; W159-Y163 HydrophobicContact CD2-CD2 3.99Å; W159-Y163 AromaticContact CD2-CE2 3.53Å; W159-Y163 HydrophobicContact CD2-CE2 3.53Å; W159-Y163 AromaticContact CE2-CD2 3.69Å; W159-Y163 AromaticContact CE2-CE2 3.21Å; W159-Y163 AromaticContact CE3-CE2 3.98Å; W159-Y163 HydrophobicContact CE3-CE2 3.98Å; W159-Y163 AromaticContact CG-CD2 3.99Å; W159-Y163 HydrophobicContact CG-CD2 3.99Å; W159-Y163 HydrophobicContact CG-CE2 4.02Å; W159-Y163 AromaticContact CH2-CE2 3.91Å; W159-Y163 HydrophobicContact CH2-CE2 3.91Å; W159-Y163 HydrophobicContact CZ2-CD2 4.28Å; W159-Y163 AromaticContact CZ2-CE2 3.44Å; W159-Y163 HydrophobicContact CZ2-CE2 3.44Å; W159-Y163 VanDerWaalsContact CZ2-CE2 3.44Å; W159-Y163 HydrophobicContact CZ3-CE2 4.15Å; W159-Y163 AromaticContact NE1-CD2 3.44Å; W159-Y163 AromaticContact NE1-CE2 3.51Å; W159-Y163 VanDerWaalsContact O-CD2 3.26Å; W159-Y163 WeakPolarHBondContact O-CD2 3.26Å; W159-Y163 PolarHBondContact O-N 3.26Å; W159-Y163 VanDerWaalsContact O-N 3.13Å; Y163-L166 HydrophobicContact CD1-CD2 4.3Å; Y163-S167 PolarHBondContact O-N 2.82Å; Y163-S167 PolarHBondContact O-OG 3.37Å; Y163-L179 HydrophobicContact CD1-CD2 3.72Å; Y163-L179 HydrophobicContact CE1-CD2 4.37Å; Y163-L182 HydrophobicContact CD1-CB 4.02Å; Y163-L182 HydrophobicContact CD1-CD1 3.71Å; Y163-L182 HydrophobicContact CD2-CB 3.95Å; Y163-L182 HydrophobicContact CE1-CB 4.39Å; Y163-L182 HydrophobicContact CE1-CD1 3.45Å; Y163-L182 VanDerWaalsContact CE1-CD1 3.45Å; Y163-L182 HydrophobicContact CE2-CB 4.35Å; Y163-L182 HydrophobicContact CE2-CD1 4.49Å; Y163-L182 HydrophobicContact CG-CB 3.78Å; Y163-L182 HydrophobicContact CG-CD1 4.32Å; Y163-V183 VanDerWaalsContact C-CG2 3.5Å
164	G	95.4	Very high	95.4	Very high	0 Å²	0	48.3 Å²	48.3	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-59.5	-57.2	172.8	0	0	0	0	0	111.1	T160 Y162 L166 S167 R180	T160-G164 WeakPolarHBondContact O-CA 3.28Å; T160-G164 PolarHBondContact O-N 3.48Å; Y162-G164 VanDerWaalsContact C-N 3.32Å; Y162-G164 PolarHBondContact O-N 2.9Å; G164-L166 PolarHBondContact O-N 3.12Å; G164-S167 VanDerWaalsContact O-CB 3.32Å; G164-S167 WeakPolarHBondContact O-CB 3.34Å; G164-S167 PolarHBondContact O-N 3.48Å; G164-R180 PolarHBondContact O-NH2 3.37Å
165	I	96.3	Very high	95.5	Very high	60 Å²	60	51.4 Å²	51.4	31%	0.308	25%	0.25	S	C	.	.	H	α-helix	trans	-63.2	-42.4	177	-66.3	170.4	0	0	0	111	L161 S167 A168 F169 A245	L161-I165 HydrophobicContact CD1-CD1 3.64Å; L161-I165 HydrophobicContact CD1-CG1 4.29Å; L161-I165 HydrophobicContact CG-CD1 4.24Å; L161-I165 WeakPolarHBondContact O-CG1 3.33Å; L161-I165 PolarHBondContact O-N 3.26Å; L161-I165 VanDerWaalsContact O-N 3.09Å; I165-S167 PolarHBondContact O-N 2.9Å; I165-S167 VanDerWaalsContact O-N 3.15Å; I165-A168 VanDerWaalsContact O-CB 3.32Å; I165-A168 WeakPolarHBondContact O-CB 3.35Å; I165-A168 PolarHBondContact O-N 2.96Å; I165-F169 HydrophobicContact CG2-CE2 4.13Å; I165-F169 WeakPolarHBondContact O-CD2 3.5Å; I165-A245 HydrophobicContact CD1-CB 4.35Å; I165-A245 HydrophobicContact CG1-CB 3.81Å
166	L	96.8	Very high	95.6	Very high	47 Å²	47	47.8 Å²	47.8	25%	0.246	23%	0.231	C	C	.	.	H	α-helix	trans	-60.8	-27	-180	-171.1	58	0	0	0	112.4	Y162 Y163 G164 A168 F169 L179	Y162-L166 HydrophobicContact CE1-CD2 4.11Å; Y162-L166 VanDerWaalsContact O-CB 3.28Å; Y162-L166 WeakPolarHBondContact O-CB 3.18Å; Y162-L166 PolarHBondContact O-N 3.24Å; Y163-L166 HydrophobicContact CD1-CD2 4.3Å; G164-L166 PolarHBondContact O-N 3.12Å; L166-A168 VanDerWaalsContact C-N 3.26Å; L166-A168 PolarHBondContact O-N 3.4Å; L166-F169 PolarHBondContact O-N 3.44Å; L166-L179 HydrophobicContact CB-CD1 4.25Å; L166-L179 HydrophobicContact CB-CD2 4.44Å; L166-L179 HydrophobicContact CD2-CD1 4.46Å; L166-L179 HydrophobicContact CD2-CD2 3.69Å; L166-L179 HydrophobicContact CG-CD1 3.91Å; L166-L179 HydrophobicContact CG-CD2 4.02Å; L166-L179 WeakPolarHBondContact O-CD1 3.38Å
167	S	96.2	Very high	95.6	Very high	0 Å²	0	49.2 Å²	49.2	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-66.9	-26.2	177.7	-58.1	0	0	0	0	113.4	Y163 G164 I165 F169 A170 L179 R180	Y163-S167 PolarHBondContact O-N 2.82Å; Y163-S167 PolarHBondContact O-OG 3.37Å; G164-S167 VanDerWaalsContact O-CB 3.32Å; G164-S167 WeakPolarHBondContact O-CB 3.34Å; G164-S167 PolarHBondContact O-N 3.48Å; I165-S167 PolarHBondContact O-N 2.9Å; I165-S167 VanDerWaalsContact O-N 3.15Å; S167-F169 PolarHBondContact O-N 3.08Å; S167-A170 VanDerWaalsContact O-CB 3.28Å; S167-A170 WeakPolarHBondContact O-CB 3.09Å; S167-A170 PolarHBondContact O-N 3.32Å; S167-L179 WeakPolarHBondContact OG-CB 3.28Å; S167-R180 PolarHBondContact OG-NE 3.45Å; S167-R180 VanDerWaalsContact OG-NE 3.13Å; S167-R180 PolarHBondContact OG-NH2 3.16Å
168	A	96	Very high	95.8	Very high	2 Å²	2	53.5 Å²	53.5	2%	0.017	27%	0.265	C	S	.	.	T	Hydrogen-bonded Turn	trans	-64.3	-25.3	176.3	0	0	0	0	0	112.7	I165 L166 A170 R238 L241 I242	I165-A168 VanDerWaalsContact O-CB 3.32Å; I165-A168 WeakPolarHBondContact O-CB 3.35Å; I165-A168 PolarHBondContact O-N 2.96Å; L166-A168 VanDerWaalsContact C-N 3.26Å; L166-A168 PolarHBondContact O-N 3.4Å; A168-A170 VanDerWaalsContact C-N 3.34Å; A168-R238 HydrophobicContact CB-CB 4.48Å; A168-R238 VanDerWaalsContact CB-O 3.3Å; A168-R238 WeakPolarHBondContact CB-O 3.39Å; A168-R238 VanDerWaalsContact O-CD 3.26Å; A168-R238 WeakPolarHBondContact O-CD 3.49Å; A168-R238 VanDerWaalsContact O-CG 3.26Å; A168-R238 WeakPolarHBondContact O-CG 3.35Å; A168-L241 HydrophobicContact CB-CB 4Å; A168-L241 HydrophobicContact CB-CD1 4.38Å; A168-I242 HydrophobicContact CB-CD1 3.86Å; A168-I242 HydrophobicContact CB-CG1 3.51Å
169	F	95.8	Very high	95.9	Very high	134 Å²	134	50.5 Å²	50.5	59%	0.588	25%	0.249	S	C	*	.	T	Hydrogen-bonded Turn	trans	-92.2	7.2	-179.8	-59.4	-80.3	0	0	0	113.1	I165 L166 S167 P171 I242	I165-F169 HydrophobicContact CG2-CE2 4.13Å; I165-F169 WeakPolarHBondContact O-CD2 3.5Å; L166-F169 PolarHBondContact O-N 3.44Å; S167-F169 PolarHBondContact O-N 3.08Å; F169-P171 VanDerWaalsContact O-CD 3.24Å; F169-P171 WeakPolarHBondContact O-CD 3.39Å; F169-I242 HydrophobicContact CZ-CD1 4.43Å
170	A	95.1	Very high	95.9	Very high	0 Å²	0	46.6 Å²	46.6	0%	0	23%	0.234	C	C	.	.			trans	-64.7	120.2	-178.1	0	0	0	0	0	111.5	S167 A168 W175 I176	S167-A170 VanDerWaalsContact O-CB 3.28Å; S167-A170 WeakPolarHBondContact O-CB 3.09Å; S167-A170 PolarHBondContact O-N 3.32Å; A168-A170 VanDerWaalsContact C-N 3.34Å; A170-W175 HydrophobicContact CB-CB 4.38Å; A170-W175 HydrophobicContact CB-CG 4.29Å; A170-I176 HydrophobicContact CB-CB 3.69Å; A170-I176 HydrophobicContact CB-CD1 4.47Å; A170-I176 HydrophobicContact CB-CG1 4.15Å
171	P	93.6	Very high	95.9	Very high	81 Å²	81	47 Å²	47	53%	0.526	24%	0.239	S	C	.	.			trans	-88.5	-20.7	178.9	33.5	-32.6	0	0	0	112.7	F169	F169-P171 VanDerWaalsContact O-CD 3.24Å; F169-P171 WeakPolarHBondContact O-CD 3.39Å
172	V	93.9	Very high	96	Very high	77 Å²	77	48.4 Å²	48.4	47%	0.467	25%	0.246	S	C	.	.	S	Bend	trans	-140.6	157.5	-173.9	-62.5	0	0	0	0	111.7	S174 W175 I176	V172-S174 PolarHBondContact O-N 3.45Å; V172-W175 HydrophobicContact CG2-CB 3.81Å; V172-W175 WeakPolarHBondContact O-CB 3.45Å; V172-W175 PolarHBondContact O-N 3.18Å; V172-W175 VanDerWaalsContact O-N 3.16Å; V172-I176 PolarHBondContact O-N 2.99Å
173	Y	93.9	Very high	96	Very high	30 Å²	30	41.7 Å²	41.7	12%	0.118	22%	0.22	C	C	.	.	H	α-helix	trans	-54.7	-49	-178.3	173.1	-102.7	0	0	0	114.1	W115 L117 Q121 L125 W175 I176 L177	W115-Y173 HydrophobicContact CE3-CD2 4.49Å; L117-Y173 HydrophobicContact CD1-CD2 3.59Å; L117-Y173 HydrophobicContact CD1-CE2 3.89Å; L117-Y173 HydrophobicContact CD2-CD2 3.79Å; L117-Y173 HydrophobicContact CD2-CE2 4.46Å; L117-Y173 HydrophobicContact CD2-CG 3.97Å; L117-Y173 HydrophobicContact CG-CD2 4.36Å; Q121-Y173 WeakPolarHBondContact CA-OH 3.45Å; Q121-Y173 HydrophobicContact CB-CE1 4.22Å; Q121-Y173 HydrophobicContact CB-CE2 3.98Å; Q121-Y173 WeakPolarHBondContact CB-OH 3.39Å; Q121-Y173 HydrophobicContact CG-CE1 4.07Å; Q121-Y173 WeakPolarHBondContact O-CE2 3.28Å; Q121-Y173 PolarHBondContact O-OH 2.83Å; L125-Y173 HydrophobicContact CB-CE2 4.43Å; Y173-W175 PolarHBondContact O-N 3.3Å; Y173-I176 WeakPolarHBondContact O-CG2 3.21Å; Y173-I176 PolarHBondContact O-N 3.48Å; Y173-L177 HydrophobicContact CE1-CD2 3.97Å; Y173-L177 WeakPolarHBondContact O-CB 3.22Å; Y173-L177 PolarHBondContact O-N 3.35Å
174	S	94.8	Very high	95.9	Very high	79 Å²	79	39.5 Å²	39.5	55%	0.552	21%	0.212	S	C	*	.	H	α-helix	trans	-61	-31.6	-178.6	-53.4	0	0	0	0	112.7	V172 V178	V172-S174 PolarHBondContact O-N 3.45Å; S174-V178 WeakPolarHBondContact O-CG2 3.42Å; S174-V178 PolarHBondContact O-N 3.28Å; S174-V178 VanDerWaalsContact O-N 3.14Å
175	W	95.9	Very high	96	Very high	127 Å²	127	42 Å²	42	48%	0.481	22%	0.222	S	C	.	.	H	α-helix	trans	-68.1	-50.4	177.8	-169.1	-73.1	0	0	0	110.6	A170 V172 Y173 L177 V178 L179	A170-W175 HydrophobicContact CB-CB 4.38Å; A170-W175 HydrophobicContact CB-CG 4.29Å; V172-W175 HydrophobicContact CG2-CB 3.81Å; V172-W175 WeakPolarHBondContact O-CB 3.45Å; V172-W175 PolarHBondContact O-N 3.18Å; V172-W175 VanDerWaalsContact O-N 3.16Å; Y173-W175 PolarHBondContact O-N 3.3Å; W175-L177 VanDerWaalsContact C-N 3.28Å; W175-L177 PolarHBondContact O-N 3.06Å; W175-V178 PolarHBondContact O-N 3.12Å; W175-L179 VanDerWaalsContact NE1-CD1 3.28Å; W175-L179 VanDerWaalsContact O-CG 3.28Å; W175-L179 WeakPolarHBondContact O-CG 3.48Å; W175-L179 PolarHBondContact O-N 3.43Å; W175-L179 VanDerWaalsContact O-N 3.08Å
176	I	95.9	Very high	95.9	Very high	0 Å²	0	39.1 Å²	39.1	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-65	-36	177.8	-157.8	169.7	0	0	0	111.4	L107 L111 W115 L125 A170 V172 Y173 V178 L179 R180 W237	L107-I176 HydrophobicContact CD2-CD1 4.23Å; L111-I176 HydrophobicContact CD1-CD1 3.67Å; W115-I176 HydrophobicContact CH2-CB 4.37Å; W115-I176 HydrophobicContact CH2-CG2 4Å; W115-I176 HydrophobicContact CZ3-CB 4.46Å; W115-I176 HydrophobicContact CZ3-CG2 3.61Å; L125-I176 HydrophobicContact CD1-CG2 3.83Å; A170-I176 HydrophobicContact CB-CB 3.69Å; A170-I176 HydrophobicContact CB-CD1 4.47Å; A170-I176 HydrophobicContact CB-CG1 4.15Å; V172-I176 PolarHBondContact O-N 2.99Å; Y173-I176 WeakPolarHBondContact O-CG2 3.21Å; Y173-I176 PolarHBondContact O-N 3.48Å; I176-V178 PolarHBondContact O-N 2.93Å; I176-L179 PolarHBondContact O-N 2.93Å; I176-R180 HydrophobicContact CG1-CG 3.98Å; I176-R180 WeakPolarHBondContact O-CB 3.26Å; I176-R180 WeakPolarHBondContact O-CG 3.48Å; I176-R180 PolarHBondContact O-N 2.98Å; I176-W237 HydrophobicContact CD1-CH2 4.28Å; I176-W237 HydrophobicContact CD1-CZ3 3.87Å
177	L	96.5	Very high	95.8	Very high	30 Å²	30	37 Å²	37	16%	0.157	20%	0.196	C	C	.	.	H	α-helix	trans	-59.7	-49.6	179.1	-178	68.9	0	0	0	111.5	L124 L125 V128 Y173 W175 G181	L124-L177 HydrophobicContact CD2-CD1 4.37Å; L124-L177 HydrophobicContact CD2-CD2 3.93Å; L124-L177 HydrophobicContact CG-CD1 3.97Å; L124-L177 HydrophobicContact CG-CD2 4.4Å; L125-L177 HydrophobicContact CD1-CD1 4.43Å; V128-L177 HydrophobicContact CB-CD1 4.07Å; V128-L177 HydrophobicContact CG1-CD1 3.78Å; V128-L177 WeakPolarHBondContact CG1-O 3.4Å; Y173-L177 HydrophobicContact CE1-CD2 3.97Å; Y173-L177 WeakPolarHBondContact O-CB 3.22Å; Y173-L177 PolarHBondContact O-N 3.35Å; W175-L177 VanDerWaalsContact C-N 3.28Å; W175-L177 PolarHBondContact O-N 3.06Å; L177-G181 PolarHBondContact O-N 2.98Å; L177-G181 VanDerWaalsContact O-N 3.07Å
178	V	97.4	Very high	95.5	Very high	91 Å²	91	37.1 Å²	37.1	55%	0.552	20%	0.198	S	C	*	.	H	α-helix	trans	-64.2	-45.6	177.8	172.8	0	0	0	0	110.7	S174 W175 I176 R180 G181 L182	S174-V178 WeakPolarHBondContact O-CG2 3.42Å; S174-V178 PolarHBondContact O-N 3.28Å; S174-V178 VanDerWaalsContact O-N 3.14Å; W175-V178 PolarHBondContact O-N 3.12Å; I176-V178 PolarHBondContact O-N 2.93Å; V178-R180 PolarHBondContact O-N 3.48Å; V178-G181 PolarHBondContact O-N 2.92Å; V178-L182 HydrophobicContact CG1-CD1 4.14Å; V178-L182 WeakPolarHBondContact O-CG 3.47Å; V178-L182 PolarHBondContact O-N 3.29Å
179	L	97.2	Very high	95.3	Very high	11 Å²	11	37 Å²	37	6%	0.058	20%	0.197	C	C	.	.	H	α-helix	trans	-63.6	-40.9	-179.2	-68.2	-178.4	0	0	0	112.9	Y163 L166 S167 W175 I176 G181 L182 V183	Y163-L179 HydrophobicContact CD1-CD2 3.72Å; Y163-L179 HydrophobicContact CE1-CD2 4.37Å; L166-L179 HydrophobicContact CB-CD1 4.25Å; L166-L179 HydrophobicContact CB-CD2 4.44Å; L166-L179 HydrophobicContact CD2-CD1 4.46Å; L166-L179 HydrophobicContact CD2-CD2 3.69Å; L166-L179 HydrophobicContact CG-CD1 3.91Å; L166-L179 HydrophobicContact CG-CD2 4.02Å; L166-L179 WeakPolarHBondContact O-CD1 3.38Å; S167-L179 WeakPolarHBondContact OG-CB 3.28Å; W175-L179 VanDerWaalsContact NE1-CD1 3.28Å; W175-L179 VanDerWaalsContact O-CG 3.28Å; W175-L179 WeakPolarHBondContact O-CG 3.48Å; W175-L179 PolarHBondContact O-N 3.43Å; W175-L179 VanDerWaalsContact O-N 3.08Å; I176-L179 PolarHBondContact O-N 2.93Å; L179-G181 VanDerWaalsContact C-N 3.31Å; L179-G181 PolarHBondContact O-N 3.01Å; L179-L182 CarbonylContact O-C 3.56Å; L179-L182 WeakPolarHBondContact O-CB 3.42Å; L179-L182 PolarHBondContact O-N 3.2Å; L179-L182 VanDerWaalsContact O-N 3.12Å; L179-V183 WeakPolarHBondContact O-CG2 3.27Å; L179-V183 PolarHBondContact O-N 3.14Å
180	R	96.2	Very high	95	Very high	1 Å²	1	30.8 Å²	30.8	0%	0.004	17%	0.17	C	C	.	.	H	α-helix	trans	-63.8	-37.8	174.7	-70.5	-67.5	108.3	173.2	-4.6	111.4	E100 L125 V128 V129 G164 S167 I176 V178 L182 V183 G184	E100-R180 IonicContact OE2-CZ 3.94Å; E100-R180 IonicContact OE2-NH1 3.32Å; E100-R180 PolarHBondContact OE2-NH1 2.88Å; E100-R180 VanDerWaalsContact OE2-NH1 3.14Å; L125-R180 HydrophobicContact CD1-CB 4.3Å; L125-R180 HydrophobicContact CD1-CG 3.93Å; V128-R180 HydrophobicContact CG1-CB 4.16Å; V129-R180 HydrophobicContact CG2-CB 3.93Å; G164-R180 PolarHBondContact O-NH2 3.37Å; S167-R180 PolarHBondContact OG-NE 3.45Å; S167-R180 VanDerWaalsContact OG-NE 3.13Å; S167-R180 PolarHBondContact OG-NH2 3.16Å; I176-R180 HydrophobicContact CG1-CG 3.98Å; I176-R180 WeakPolarHBondContact O-CB 3.26Å; I176-R180 WeakPolarHBondContact O-CG 3.48Å; I176-R180 PolarHBondContact O-N 2.98Å; V178-R180 PolarHBondContact O-N 3.48Å; R180-L182 VanDerWaalsContact C-N 3.31Å; R180-L182 PolarHBondContact O-N 2.89Å; R180-V183 WeakPolarHBondContact O-CB 3.14Å; R180-V183 PolarHBondContact O-N 3.39Å; R180-G184 PolarHBondContact O-N 3.2Å
181	G	96.9	Very high	94.7	Very high	11 Å²	11	32.8 Å²	32.8	11%	0.113	18%	0.183	C	C	.	.	H	α-helix	trans	-59.1	-41.3	170.5	0	0	0	0	0	112.7	L177 V178 L179 G184 F185	L177-G181 PolarHBondContact O-N 2.98Å; L177-G181 VanDerWaalsContact O-N 3.07Å; V178-G181 PolarHBondContact O-N 2.92Å; L179-G181 VanDerWaalsContact C-N 3.31Å; L179-G181 PolarHBondContact O-N 3.01Å; G181-G184 PolarHBondContact O-N 2.9Å; G181-F185 PolarHBondContact O-N 3.21Å
182	L	97.6	Very high	94.4	Very high	48 Å²	48	30 Å²	30	25%	0.251	16%	0.163	S	C	.	.	H	α-helix	trans	-71.6	-33.4	176.6	-63.5	172.7	0	0	0	112.9	W159 Y163 V178 L179 R180 F185 G186	W159-L182 VanDerWaalsContact CD1-O 3.29Å; W159-L182 HydrophobicContact CZ2-CD2 4.15Å; W159-L182 PolarHBondContact NE1-O 3.48Å; Y163-L182 HydrophobicContact CD1-CB 4.02Å; Y163-L182 HydrophobicContact CD1-CD1 3.71Å; Y163-L182 HydrophobicContact CD2-CB 3.95Å; Y163-L182 HydrophobicContact CE1-CB 4.39Å; Y163-L182 HydrophobicContact CE1-CD1 3.45Å; Y163-L182 VanDerWaalsContact CE1-CD1 3.45Å; Y163-L182 HydrophobicContact CE2-CB 4.35Å; Y163-L182 HydrophobicContact CE2-CD1 4.49Å; Y163-L182 HydrophobicContact CG-CB 3.78Å; Y163-L182 HydrophobicContact CG-CD1 4.32Å; V178-L182 HydrophobicContact CG1-CD1 4.14Å; V178-L182 WeakPolarHBondContact O-CG 3.47Å; V178-L182 PolarHBondContact O-N 3.29Å; L179-L182 CarbonylContact O-C 3.56Å; L179-L182 WeakPolarHBondContact O-CB 3.42Å; L179-L182 PolarHBondContact O-N 3.2Å; L179-L182 VanDerWaalsContact O-N 3.12Å; R180-L182 VanDerWaalsContact C-N 3.31Å; R180-L182 PolarHBondContact O-N 2.89Å; L182-F185 WeakPolarHBondContact O-CB 3.35Å; L182-F185 PolarHBondContact O-N 3.33Å; L182-G186 PolarHBondContact O-N 2.83Å
183	V	97.1	Very high	94.2	Very high	1 Å²	1	26.3 Å²	26.3	1%	0.006	14%	0.141	C	C	.	.	H	α-helix	trans	-61.9	-49.2	169.6	167.9	0	0	0	0	109.8	E100 T160 Y163 L179 R180 F185 G186 I187	E100-V183 HydrophobicContact CG-CG1 4.38Å; T160-V183 HydrophobicContact CG2-CG1 4.05Å; Y163-V183 VanDerWaalsContact C-CG2 3.5Å; L179-V183 WeakPolarHBondContact O-CG2 3.27Å; L179-V183 PolarHBondContact O-N 3.14Å; R180-V183 WeakPolarHBondContact O-CB 3.14Å; R180-V183 PolarHBondContact O-N 3.39Å; V183-F185 PolarHBondContact O-N 3.24Å; V183-G186 WeakPolarHBondContact O-CA 3.26Å; V183-G186 PolarHBondContact O-N 3.06Å; V183-I187 HydrophobicContact CG1-CD1 3.77Å; V183-I187 HydrophobicContact CG1-CG1 4.42Å; V183-I187 WeakPolarHBondContact O-CG1 3.42Å; V183-I187 PolarHBondContact O-N 3.16Å
184	G	95.9	Very high	93.9	Very high	0 Å²	0	26.2 Å²	26.2	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-56.8	-38.4	173.3	0	0	0	0	0	112.9	V129 G132 M133 R180 G181 G186 I187 G188	V129-G184 WeakPolarHBondContact O-CA 3.41Å; G132-G184 VanDerWaalsContact C-C 3.5Å; G132-G184 CarbonylContact C-O 3.57Å; M133-G184 WeakPolarHBondContact CA-O 3.41Å; M133-G184 PolarHBondContact N-O 2.74Å; M133-G184 VanDerWaalsContact N-O 3.16Å; R180-G184 PolarHBondContact O-N 3.2Å; G181-G184 PolarHBondContact O-N 2.9Å; G184-G186 VanDerWaalsContact C-N 3.35Å; G184-G186 PolarHBondContact O-N 3.05Å; G184-I187 PolarHBondContact O-N 3.43Å; G184-G188 PolarHBondContact O-N 2.82Å
185	F	96.2	Very high	93.5	Very high	52 Å²	52	25 Å²	25	23%	0.228	13%	0.133	C	C	.	.	H	α-helix	trans	-60.1	-42	172.7	-168.6	-79	0	0	0	112	G132 S136 L139 W140 W159 G181 L182 V183	G132-F185 WeakPolarHBondContact O-CA 3.42Å; S136-F185 WeakPolarHBondContact CB-O 3.26Å; S136-F185 PolarHBondContact OG-O 3.13Å; L139-F185 HydrophobicContact CD1-CE2 3.83Å; L139-F185 HydrophobicContact CD1-CZ 3.59Å; W140-F185 HydrophobicContact CZ2-CD1 4.04Å; W140-F185 AromaticContact CZ2-CE1 3.84Å; W140-F185 HydrophobicContact CZ2-CE1 3.84Å; W140-F185 PolarHBondContact NE1-O 2.9Å; W159-F185 HydrophobicContact CZ2-CD1 4.45Å; W159-F185 AromaticContact NE1-CD1 3.95Å; G181-F185 PolarHBondContact O-N 3.21Å; L182-F185 WeakPolarHBondContact O-CB 3.35Å; L182-F185 PolarHBondContact O-N 3.33Å; V183-F185 PolarHBondContact O-N 3.24Å
186	G	95.3	Very high	93.2	Very high	0 Å²	0	19 Å²	19	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-68.4	-41.7	175.2	0	0	0	0	0	113.1	T160 L182 V183 G184 G188 G189	T160-G186 VanDerWaalsContact OG1-CA 3.25Å; T160-G186 WeakPolarHBondContact OG1-CA 3.35Å; L182-G186 PolarHBondContact O-N 2.83Å; V183-G186 WeakPolarHBondContact O-CA 3.26Å; V183-G186 PolarHBondContact O-N 3.06Å; G184-G186 VanDerWaalsContact C-N 3.35Å; G184-G186 PolarHBondContact O-N 3.05Å; G186-G188 PolarHBondContact O-N 2.97Å; G186-G189 PolarHBondContact O-N 2.9Å
187	I	94.1	Very high	93	Very high	1 Å²	1	19 Å²	19	1%	0.005	11%	0.11	C	C	.	.	H	α-helix	trans	-56.7	-34.8	179.3	-73.4	169.1	0	0	0	112.5	D97 E100 V129 M133 T160 V183 G184 G189 V190	D97-I187 WeakPolarHBondContact OD1-CG2 3.32Å; E100-I187 HydrophobicContact CB-CD1 3.52Å; E100-I187 HydrophobicContact CB-CG1 4.5Å; E100-I187 HydrophobicContact CG-CD1 4.05Å; V129-I187 HydrophobicContact CG1-CD1 4.33Å; M133-I187 HydrophobicContact CE-CG2 3.59Å; M133-I187 HydrophobicContact CG-CG2 4.25Å; M133-I187 HydrophobicContact SD-CG2 3.77Å; T160-I187 HydrophobicContact CG2-CG1 3.92Å; T160-I187 PolarHBondContact OG1-N 2.88Å; V183-I187 HydrophobicContact CG1-CD1 3.77Å; V183-I187 HydrophobicContact CG1-CG1 4.42Å; V183-I187 WeakPolarHBondContact O-CG1 3.42Å; V183-I187 PolarHBondContact O-N 3.16Å; G184-I187 PolarHBondContact O-N 3.43Å; I187-G189 PolarHBondContact O-N 2.94Å; I187-V190 WeakPolarHBondContact O-CB 3.3Å; I187-V190 WeakPolarHBondContact O-CG2 3.45Å; I187-V190 PolarHBondContact O-N 3.41Å
188	G	91.1	Very high	92.5	Very high	4 Å²	4	17.8 Å²	17.8	4%	0.041	11%	0.105	C	C	.	.	T	Hydrogen-bonded Turn	trans	-58.1	-17.3	176.3	0	0	0	0	0	115	S136 G184 G186	S136-G188 WeakPolarHBondContact OG-CA 3.37Å; G184-G188 PolarHBondContact O-N 2.82Å; G186-G188 PolarHBondContact O-N 2.97Å
189	G	90.4	Very high	92	Very high	0 Å²	0	15.3 Å²	15.3	0%	0	9%	0.087	C	C	.	.	T	Hydrogen-bonded Turn	trans	-90.3	-9.9	175.1	0	0	0	0	0	114.9	W140 G186 I187 Q192	W140-G189 VanDerWaalsContact CD1-CA 3.48Å; W140-G189 VanDerWaalsContact CG-CA 3.48Å; G186-G189 PolarHBondContact O-N 2.9Å; I187-G189 PolarHBondContact O-N 2.94Å; G189-Q192 VanDerWaalsContact O-CB 3.28Å; G189-Q192 WeakPolarHBondContact O-CB 3.44Å; G189-Q192 VanDerWaalsContact O-CG 3.22Å; G189-Q192 WeakPolarHBondContact O-CG 3.33Å; G189-Q192 PolarHBondContact O-N 3.08Å
190	V	90.6	Very high	91.7	Very high	2 Å²	2	15 Å²	15	1%	0.012	9%	0.085	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65.1	-36.2	-178.5	179.2	0	0	0	0	113.6	A93 W94 D97 I187 Q192 S193	A93-V190 HydrophobicContact CB-CG1 4.24Å; A93-V190 WeakPolarHBondContact O-CG1 3.4Å; W94-V190 HydrophobicContact CE3-CG1 3.98Å; W94-V190 HydrophobicContact CZ3-CG1 4.44Å; D97-V190 HydrophobicContact CB-CB 4.36Å; D97-V190 HydrophobicContact CB-CG1 3.97Å; D97-V190 HydrophobicContact CB-CG2 4.42Å; I187-V190 WeakPolarHBondContact O-CB 3.3Å; I187-V190 WeakPolarHBondContact O-CG2 3.45Å; I187-V190 PolarHBondContact O-N 3.41Å; V190-Q192 PolarHBondContact O-N 3.38Å; V190-S193 VanDerWaalsContact O-CB 3.31Å; V190-S193 WeakPolarHBondContact O-CB 3.32Å; V190-S193 PolarHBondContact O-N 3.12Å; V190-S193 PolarHBondContact O-OG 3.11Å
191	P	87.6	Confident	91.3	Very high	43 Å²	43	15.3 Å²	15.3	28%	0.279	9%	0.087	S	C	.	.	T	Hydrogen-bonded Turn	trans	-56.5	-15.2	176.3	-27.9	36.1	0	0	0	115.2	W94 S193 V194 T195	W94-P191 HydrophobicContact CZ3-CG 4.46Å; P191-S193 PolarHBondContact O-N 3.46Å; P191-V194 PolarHBondContact O-N 3.45Å; P191-T195 PolarHBondContact O-N 2.93Å; P191-T195 PolarHBondContact O-OG1 3.41Å
192	Q	87.9	Confident	90.8	Very high	22 Å²	22	15.2 Å²	15.2	10%	0.103	8%	0.084	C	C	.	.	H	α-helix	trans	-63.7	-25.1	170.6	-58.3	-58.5	-42.8	0	0	112.5	S144 R149 G189 V190 T195 L196	S144-Q192 VanDerWaalsContact CB-OE1 3.32Å; S144-Q192 PolarHBondContact OG-OE1 3.38Å; R149-Q192 VanDerWaalsContact NH1-OE1 3.17Å; G189-Q192 VanDerWaalsContact O-CB 3.28Å; G189-Q192 WeakPolarHBondContact O-CB 3.44Å; G189-Q192 VanDerWaalsContact O-CG 3.22Å; G189-Q192 WeakPolarHBondContact O-CG 3.33Å; G189-Q192 PolarHBondContact O-N 3.08Å; V190-Q192 PolarHBondContact O-N 3.38Å; Q192-T195 PolarHBondContact O-N 3.08Å; Q192-L196 VanDerWaalsContact O-CB 3.26Å; Q192-L196 WeakPolarHBondContact O-CB 3.24Å; Q192-L196 PolarHBondContact O-N 3.34Å
193	S	90.1	Very high	89.8	Confident	0 Å²	0	17.7 Å²	17.7	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-64	-44.2	174.8	72.1	0	0	0	0	112	V190 P191 T195 L196 Y197	V190-S193 VanDerWaalsContact O-CB 3.31Å; V190-S193 WeakPolarHBondContact O-CB 3.32Å; V190-S193 PolarHBondContact O-N 3.12Å; V190-S193 PolarHBondContact O-OG 3.11Å; P191-S193 PolarHBondContact O-N 3.46Å; S193-T195 VanDerWaalsContact C-N 3.34Å; S193-L196 PolarHBondContact O-N 2.98Å; S193-Y197 WeakPolarHBondContact O-CB 3.48Å; S193-Y197 PolarHBondContact O-N 2.99Å
194	V	87.3	Confident	88.8	Confident	28 Å²	28	26 Å²	26	17%	0.17	13%	0.132	C	C	.	.	H	α-helix	trans	-66.8	-40.2	176.6	-174	0	0	0	0	110.4	W94 P191 Y197 A198 I210 I213	W94-V194 HydrophobicContact CD2-CG2 4.27Å; W94-V194 HydrophobicContact CE3-CG2 3.86Å; W94-V194 HydrophobicContact CH2-CG2 4.45Å; W94-V194 HydrophobicContact CZ3-CG2 3.98Å; P191-V194 PolarHBondContact O-N 3.45Å; V194-Y197 PolarHBondContact O-N 2.9Å; V194-A198 VanDerWaalsContact O-CB 3.25Å; V194-A198 WeakPolarHBondContact O-CB 3.31Å; V194-A198 PolarHBondContact O-N 3.38Å; V194-I210 HydrophobicContact CG1-CG2 4.4Å; V194-I213 HydrophobicContact CG2-CG2 4.19Å
195	T	86.8	Confident	87.9	Confident	53 Å²	53	27 Å²	27	33%	0.325	14%	0.14	S	C	.	.	H	α-helix	trans	-64	-48.7	177.3	-54.5	0	0	0	0	111	P191 Q192 S193 Y197 A198 E199	P191-T195 PolarHBondContact O-N 2.93Å; P191-T195 PolarHBondContact O-OG1 3.41Å; Q192-T195 PolarHBondContact O-N 3.08Å; S193-T195 VanDerWaalsContact C-N 3.34Å; T195-Y197 PolarHBondContact O-N 3.31Å; T195-A198 PolarHBondContact O-N 3.12Å; T195-E199 WeakPolarHBondContact O-CG 3.36Å; T195-E199 PolarHBondContact O-N 3.13Å
196	L	89.7	Confident	87.2	Confident	0 Å²	0	29.1 Å²	29.1	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-58.5	-48.8	175.9	-178.2	64.2	0	0	0	110.7	R149 L153 Q192 S193 A198 E199 F200 L258	R149-L196 HydrophobicContact CB-CB 4.45Å; R149-L196 HydrophobicContact CB-CD1 3.78Å; L153-L196 HydrophobicContact CD2-CD2 4.39Å; Q192-L196 VanDerWaalsContact O-CB 3.26Å; Q192-L196 WeakPolarHBondContact O-CB 3.24Å; Q192-L196 PolarHBondContact O-N 3.34Å; S193-L196 PolarHBondContact O-N 2.98Å; L196-A198 VanDerWaalsContact C-N 3.32Å; L196-A198 PolarHBondContact O-N 3.42Å; L196-E199 PolarHBondContact O-N 2.84Å; L196-E199 VanDerWaalsContact O-N 3.16Å; L196-F200 HydrophobicContact CD1-CD2 4.36Å; L196-F200 HydrophobicContact CD1-CE2 3.58Å; L196-F200 HydrophobicContact CD1-CZ 4.47Å; L196-F200 HydrophobicContact CG-CD2 4.46Å; L196-F200 HydrophobicContact CG-CE2 4Å; L196-F200 WeakPolarHBondContact O-CD2 3.47Å; L196-L258 HydrophobicContact CD2-CD1 3.84Å; L196-L258 HydrophobicContact CD2-CD2 3.79Å; L196-L258 HydrophobicContact CD2-CG 3.97Å
197	Y	90.8	Very high	86.2	Confident	0 Å²	0	32.3 Å²	32.3	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-58.5	-43.8	177.8	-177.6	-127.5	0	0	0	112.2	L86 S87 S193 V194 T195 E199 F200 L201 C209 I213	L86-Y197 HydrophobicContact CB-CD2 4.45Å; L86-Y197 HydrophobicContact CD2-CD2 3.88Å; L86-Y197 HydrophobicContact CG-CD2 3.92Å; S87-Y197 WeakPolarHBondContact CB-OH 3.36Å; S87-Y197 PolarHBondContact OG-OH 3.28Å; S193-Y197 WeakPolarHBondContact O-CB 3.48Å; S193-Y197 PolarHBondContact O-N 2.99Å; V194-Y197 PolarHBondContact O-N 2.9Å; T195-Y197 PolarHBondContact O-N 3.31Å; Y197-E199 PolarHBondContact O-N 3.14Å; Y197-F200 PolarHBondContact O-N 3.08Å; Y197-F200 VanDerWaalsContact O-N 3.12Å; Y197-L201 HydrophobicContact CD1-CD1 3.59Å; Y197-L201 HydrophobicContact CD1-CG 4.5Å; Y197-L201 HydrophobicContact CD2-CD1 4.32Å; Y197-L201 HydrophobicContact CD2-CG 4.41Å; Y197-L201 HydrophobicContact CE1-CD1 3.5Å; Y197-L201 HydrophobicContact CE1-CD2 4.47Å; Y197-L201 HydrophobicContact CE1-CG 4.37Å; Y197-L201 HydrophobicContact CE2-CD1 4.15Å; Y197-L201 HydrophobicContact CE2-CD2 4Å; Y197-L201 HydrophobicContact CE2-CG 4.16Å; Y197-L201 HydrophobicContact CG-CD1 4.06Å; Y197-L201 WeakPolarHBondContact O-CG 3.28Å; Y197-C209 HydrophobicContact CE1-CB 3.75Å; Y197-C209 WeakPolarHBondContact OH-CB 3.32Å; Y197-I213 HydrophobicContact CD1-CD1 3.18Å; Y197-I213 HydrophobicContact CD1-CG1 3.96Å; Y197-I213 HydrophobicContact CE1-CD1 3.66Å; Y197-I213 HydrophobicContact CE1-CG1 3.92Å; Y197-I213 HydrophobicContact CG-CD1 3.89Å
198	A	86.2	Confident	85.5	Confident	6 Å²	6	39.9 Å²	39.9	5%	0.05	21%	0.206	C	C	.	.	H	α-helix	trans	-63.6	-23.8	179.4	0	0	0	0	0	114.1	V194 T195 L196 I210	V194-A198 VanDerWaalsContact O-CB 3.25Å; V194-A198 WeakPolarHBondContact O-CB 3.31Å; V194-A198 PolarHBondContact O-N 3.38Å; T195-A198 PolarHBondContact O-N 3.12Å; L196-A198 VanDerWaalsContact C-N 3.32Å; L196-A198 PolarHBondContact O-N 3.42Å; A198-I210 HydrophobicContact CB-CD1 4.23Å
199	E	88.1	Confident	85.2	Confident	39 Å²	39	40.2 Å²	40.2	18%	0.182	21%	0.208	C	C	.	.	H	α-helix	trans	-78.1	-19.2	176.7	-70.8	175.3	-169.7	0	0	113	R149 T195 L196 Y197 S261	R149-E199 IonicContact NE-OE1 3.9Å; R149-E199 PolarHBondContact NE-OE1 3.4Å; T195-E199 WeakPolarHBondContact O-CG 3.36Å; T195-E199 PolarHBondContact O-N 3.13Å; L196-E199 PolarHBondContact O-N 2.84Å; L196-E199 VanDerWaalsContact O-N 3.16Å; Y197-E199 PolarHBondContact O-N 3.14Å; E199-S261 WeakPolarHBondContact OE2-CB 3.49Å; E199-S261 PolarHBondContact OE2-OG 2.88Å
200	F	89	Confident	84.7	Confident	4 Å²	4	42.6 Å²	42.6	2%	0.018	22%	0.22	C	C	.	.	S	Bend	trans	-98.6	2.6	176.8	-68.9	-76.5	0	0	0	114	F82 L86 L196 Y197 P259 E260 T277 I281	F82-F200 HydrophobicContact CE1-CB 4.32Å; F82-F200 AromaticContact CE1-CD1 3.77Å; F82-F200 HydrophobicContact CE1-CD1 3.77Å; F82-F200 HydrophobicContact CE1-CE1 4.25Å; F82-F200 HydrophobicContact CE1-CG 4.09Å; F82-F200 HydrophobicContact CZ-CD1 4.2Å; F82-F200 HydrophobicContact CZ-CE1 4.2Å; L86-F200 HydrophobicContact CD2-CB 3.62Å; L86-F200 HydrophobicContact CD2-CD2 3.32Å; L86-F200 HydrophobicContact CD2-CE2 4.1Å; L86-F200 HydrophobicContact CD2-CG 3.65Å; L196-F200 HydrophobicContact CD1-CD2 4.36Å; L196-F200 HydrophobicContact CD1-CE2 3.58Å; L196-F200 HydrophobicContact CD1-CZ 4.47Å; L196-F200 HydrophobicContact CG-CD2 4.46Å; L196-F200 HydrophobicContact CG-CE2 4Å; L196-F200 WeakPolarHBondContact O-CD2 3.47Å; Y197-F200 PolarHBondContact O-N 3.08Å; Y197-F200 VanDerWaalsContact O-N 3.12Å; F200-P259 HydrophobicContact CE1-CG 4.48Å; F200-P259 HydrophobicContact CZ-CB 4.47Å; F200-P259 HydrophobicContact CZ-CG 4.06Å; F200-E260 WeakPolarHBondContact CZ-O 3.42Å; F200-T277 HydrophobicContact CE1-CG2 3.94Å; F200-T277 HydrophobicContact CZ-CG2 4.47Å; F200-I281 HydrophobicContact CD1-CD1 3.59Å; F200-I281 HydrophobicContact CE1-CD1 3.84Å
201	L	88.1	Confident	84.1	Confident	8 Å²	8	44.5 Å²	44.5	4%	0.042	23%	0.229	C	C	.	.	S	Bend	trans	-101	134.6	-175.1	-74.4	170.2	0	0	0	112	F79 Q83 Y197 R206 C209	F79-L201 HydrophobicContact CD2-CD2 3.77Å; F79-L201 HydrophobicContact CE2-CD2 3.76Å; Q83-L201 HydrophobicContact CB-CD2 4.38Å; Q83-L201 HydrophobicContact CG-CD2 4.29Å; Y197-L201 HydrophobicContact CD1-CD1 3.59Å; Y197-L201 HydrophobicContact CD1-CG 4.5Å; Y197-L201 HydrophobicContact CD2-CD1 4.32Å; Y197-L201 HydrophobicContact CD2-CG 4.41Å; Y197-L201 HydrophobicContact CE1-CD1 3.5Å; Y197-L201 HydrophobicContact CE1-CD2 4.47Å; Y197-L201 HydrophobicContact CE1-CG 4.37Å; Y197-L201 HydrophobicContact CE2-CD1 4.15Å; Y197-L201 HydrophobicContact CE2-CD2 4Å; Y197-L201 HydrophobicContact CE2-CG 4.16Å; Y197-L201 HydrophobicContact CG-CD1 4.06Å; Y197-L201 WeakPolarHBondContact O-CG 3.28Å; L201-R206 HydrophobicContact CB-CB 4.2Å; L201-R206 HydrophobicContact CB-CG 4.29Å; L201-C209 HydrophobicContact CD1-CB 3.46Å; L201-C209 VanDerWaalsContact CD1-CB 3.46Å; L201-C209 HydrophobicContact CD2-CB 3.81Å; L201-C209 HydrophobicContact CG-CB 4.29Å
202	P	86.1	Confident	83.8	Confident	9 Å²	9	45.4 Å²	45.4	6%	0.058	23%	0.232	C	C	.	.			trans	-67.2	150.7	171.6	29.3	-33.6	0	0	0	110.5	E75 F79 K204 A205 R206	E75-P202 WeakPolarHBondContact OE2-CA 3.41Å; E75-P202 VanDerWaalsContact OE2-CB 3.28Å; E75-P202 WeakPolarHBondContact OE2-CB 3.28Å; F79-P202 HydrophobicContact CB-CG 4.07Å; P202-K204 VanDerWaalsContact C-N 3.27Å; P202-K204 PolarHBondContact O-N 3.09Å; P202-A205 HydrophobicContact CG-CB 4.02Å; P202-A205 PolarHBondContact O-N 3.19Å; P202-A205 VanDerWaalsContact O-N 3.11Å; P202-R206 WeakPolarHBondContact O-CB 3.46Å; P202-R206 PolarHBondContact O-N 3.42Å
203	M	77.7	Confident	83.7	Confident	100 Å²	100	44.4 Å²	44.4	49%	0.493	23%	0.227	S	C	.	.	H	α-helix	trans	-59.2	-38.4	-170.1	-75.9	-68.4	-76.5	0	0	112.3	E75 A205 L517	E75-M203 PolarHBondContact OE2-N 3.46Å; M203-A205 PolarHBondContact O-N 3.07Å; M203-L517 HydrophobicContact CE-CD1 4.27Å
204	K	75.2	Confident	83.3	Confident	175 Å²	175	45.5 Å²	45.5	76%	0.761	23%	0.232	S	C	*	.	H	α-helix	trans	-65.9	-33.9	-179.8	-64.6	176.7	-173.6	169.1	0	113.8	E75 P202	E75-K204 WeakPolarHBondContact OE1-CE 3.49Å; E75-K204 IonicContact OE1-NZ 3.41Å; P202-K204 VanDerWaalsContact C-N 3.27Å; P202-K204 PolarHBondContact O-N 3.09Å
205	A	78.2	Confident	83.4	Confident	22 Å²	22	46.4 Å²	46.4	18%	0.182	24%	0.238	C	C	.	.	H	α-helix	trans	-97.2	-16.8	-177.3	0	0	0	0	0	112.9	F79 P202 M203 A207 K208 C209	F79-A205 HydrophobicContact CD2-CB 4.47Å; P202-A205 HydrophobicContact CG-CB 4.02Å; P202-A205 PolarHBondContact O-N 3.19Å; P202-A205 VanDerWaalsContact O-N 3.11Å; M203-A205 PolarHBondContact O-N 3.07Å; A205-A207 PolarHBondContact O-N 3.26Å; A205-K208 PolarHBondContact O-N 3.42Å; A205-C209 WeakPolarHBondContact O-CB 3.19Å; A205-C209 PolarHBondContact O-N 3.23Å; A205-C209 PolarHBondContact O-SG 3.38Å
206	R	80.4	Confident	83.7	Confident	96 Å²	96	45.6 Å²	45.6	36%	0.362	23%	0.23	S	C	.	.	H	α-helix	trans	-52.6	-51.3	-170.9	-175.3	174.8	178.6	172.2	6.2	113.7	L201 P202 K208 C209 I210	L201-R206 HydrophobicContact CB-CB 4.2Å; L201-R206 HydrophobicContact CB-CG 4.29Å; P202-R206 WeakPolarHBondContact O-CB 3.46Å; P202-R206 PolarHBondContact O-N 3.42Å; R206-K208 PolarHBondContact O-N 3.3Å; R206-C209 PolarHBondContact O-N 3.35Å; R206-I210 HydrophobicContact CG-CD1 3.82Å; R206-I210 WeakPolarHBondContact O-CG1 3.22Å; R206-I210 PolarHBondContact O-N 3.15Å
207	A	74.3	Confident	83.8	Confident	67 Å²	67	46.4 Å²	46.4	55%	0.554	23%	0.233	S	C	*	.	H	α-helix	trans	-61.9	-45	-178.3	0	0	0	0	0	112.4	A205 C209 I210 L211	A205-A207 PolarHBondContact O-N 3.26Å; A207-C209 VanDerWaalsContact C-N 3.32Å; A207-C209 PolarHBondContact O-N 3.2Å; A207-I210 PolarHBondContact O-N 3.2Å; A207-L211 WeakPolarHBondContact O-CG 3.35Å; A207-L211 PolarHBondContact O-N 3.42Å; A207-L211 VanDerWaalsContact O-N 3.09Å
208	K	80.3	Confident	83.9	Confident	160 Å²	160	46.5 Å²	46.5	70%	0.696	23%	0.234	S	C	*	.	H	α-helix	trans	-63.1	-39.5	177.8	-64.5	-178.7	-176.3	176.8	0	111.8	A205 R206 L211 L212	A205-K208 PolarHBondContact O-N 3.42Å; R206-K208 PolarHBondContact O-N 3.3Å; K208-L211 PolarHBondContact O-N 3.3Å; K208-L212 PolarHBondContact O-N 3.28Å
209	C	84.1	Confident	84.3	Confident	11 Å²	11	49.3 Å²	49.3	7%	0.074	25%	0.247	C	C	.	.	H	α-helix	trans	-71.2	-37.5	-179.5	-67.5	0	0	0	0	112.5	F79 Y197 L201 A205 R206 A207 L211 L212 I213	F79-C209 VanDerWaalsContact CE2-SG 3.57Å; Y197-C209 HydrophobicContact CE1-CB 3.75Å; Y197-C209 WeakPolarHBondContact OH-CB 3.32Å; L201-C209 HydrophobicContact CD1-CB 3.46Å; L201-C209 VanDerWaalsContact CD1-CB 3.46Å; L201-C209 HydrophobicContact CD2-CB 3.81Å; L201-C209 HydrophobicContact CG-CB 4.29Å; A205-C209 WeakPolarHBondContact O-CB 3.19Å; A205-C209 PolarHBondContact O-N 3.23Å; A205-C209 PolarHBondContact O-SG 3.38Å; R206-C209 PolarHBondContact O-N 3.35Å; A207-C209 VanDerWaalsContact C-N 3.32Å; A207-C209 PolarHBondContact O-N 3.2Å; C209-L211 VanDerWaalsContact C-N 3.34Å; C209-L212 WeakPolarHBondContact O-CB 3.32Å; C209-L212 PolarHBondContact O-N 3.07Å; C209-I213 PolarHBondContact O-N 3.45Å
210	I	80.8	Confident	84.7	Confident	50 Å²	50	47.5 Å²	47.5	26%	0.256	24%	0.239	S	C	.	.	H	α-helix	trans	-64.7	-41.8	173.7	-68.4	168.4	0	0	0	110.1	V194 A198 R206 A207 L212 I213	V194-I210 HydrophobicContact CG1-CG2 4.4Å; A198-I210 HydrophobicContact CB-CD1 4.23Å; R206-I210 HydrophobicContact CG-CD1 3.82Å; R206-I210 WeakPolarHBondContact O-CG1 3.22Å; R206-I210 PolarHBondContact O-N 3.15Å; A207-I210 PolarHBondContact O-N 3.2Å; I210-L212 VanDerWaalsContact C-N 3.29Å; I210-L212 PolarHBondContact O-N 2.99Å; I210-I213 WeakPolarHBondContact O-CB 3.49Å; I210-I213 PolarHBondContact O-N 3.37Å; I210-I213 VanDerWaalsContact O-N 3.14Å
211	L	77.9	Confident	85	Confident	41 Å²	41	47.4 Å²	47.4	22%	0.215	24%	0.238	C	C	.	.	H	α-helix	trans	-62.7	-35.1	173.4	-70.3	168.4	0	0	0	112.6	A207 K208 C209 I213 E214 L391 V446	A207-L211 WeakPolarHBondContact O-CG 3.35Å; A207-L211 PolarHBondContact O-N 3.42Å; A207-L211 VanDerWaalsContact O-N 3.09Å; K208-L211 PolarHBondContact O-N 3.3Å; C209-L211 VanDerWaalsContact C-N 3.34Å; L211-I213 VanDerWaalsContact C-N 3.27Å; L211-I213 PolarHBondContact O-N 2.77Å; L211-E214 WeakPolarHBondContact O-CB 3.39Å; L211-E214 PolarHBondContact O-N 3.01Å; L211-L391 HydrophobicContact CD1-CD2 3.68Å; L211-L391 HydrophobicContact CD2-CD2 4.11Å; L211-L391 HydrophobicContact CG-CD2 4.44Å; L211-V446 HydrophobicContact CD2-CG2 4.23Å
212	L	81.7	Confident	85.3	Confident	63 Å²	63	47.9 Å²	47.9	33%	0.33	24%	0.242	S	C	.	.	H	α-helix	trans	-65	-30.9	175.3	-169.3	71.5	0	0	0	112.1	W84 K208 C209 I210 E214 V215	W84-L212 HydrophobicContact CH2-CD2 3.8Å; W84-L212 HydrophobicContact CZ3-CD2 3.98Å; K208-L212 PolarHBondContact O-N 3.28Å; C209-L212 WeakPolarHBondContact O-CB 3.32Å; C209-L212 PolarHBondContact O-N 3.07Å; I210-L212 VanDerWaalsContact C-N 3.29Å; I210-L212 PolarHBondContact O-N 2.99Å; L212-E214 VanDerWaalsContact C-N 3.25Å; L212-E214 PolarHBondContact O-N 3.36Å; L212-V215 HydrophobicContact CD1-CG2 4.35Å; L212-V215 VanDerWaalsContact O-CB 3.29Å; L212-V215 WeakPolarHBondContact O-CB 3.41Å; L212-V215 PolarHBondContact O-N 2.97Å; L212-V215 VanDerWaalsContact O-N 3.11Å
213	I	83.9	Confident	85.8	Confident	0 Å²	0	51.7 Å²	51.7	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-62.3	-34.7	173.9	-76.3	-171.9	0	0	0	111.4	W94 V194 Y197 C209 I210 L211 V215 F216	W94-I213 HydrophobicContact CB-CG2 4.07Å; W94-I213 VanDerWaalsContact CD1-O 3.27Å; W94-I213 HydrophobicContact CD2-CG2 4.15Å; W94-I213 HydrophobicContact CG-CG2 3.64Å; V194-I213 HydrophobicContact CG2-CG2 4.19Å; Y197-I213 HydrophobicContact CD1-CD1 3.18Å; Y197-I213 HydrophobicContact CD1-CG1 3.96Å; Y197-I213 HydrophobicContact CE1-CD1 3.66Å; Y197-I213 HydrophobicContact CE1-CG1 3.92Å; Y197-I213 HydrophobicContact CG-CD1 3.89Å; C209-I213 PolarHBondContact O-N 3.45Å; I210-I213 WeakPolarHBondContact O-CB 3.49Å; I210-I213 PolarHBondContact O-N 3.37Å; I210-I213 VanDerWaalsContact O-N 3.14Å; L211-I213 VanDerWaalsContact C-N 3.27Å; L211-I213 PolarHBondContact O-N 2.77Å; I213-V215 PolarHBondContact O-N 3.31Å; I213-V215 VanDerWaalsContact O-N 3.17Å; I213-F216 WeakPolarHBondContact O-CA 3Å; I213-F216 VanDerWaalsContact O-CB 3.29Å; I213-F216 WeakPolarHBondContact O-CB 3.25Å; I213-F216 PolarHBondContact O-N 2.82Å
214	E	83.1	Confident	86.7	Confident	24 Å²	24	46.9 Å²	46.9	11%	0.112	23%	0.234	C	C	.	.	H	α-helix	trans	-63.5	-22.1	176.6	-60.2	-62.2	164.2	0	0	112.8	W94 L211 L212 F216 W217 A218	W94-E214 PolarHBondContact NE1-OE2 3.08Å; L211-E214 WeakPolarHBondContact O-CB 3.39Å; L211-E214 PolarHBondContact O-N 3.01Å; L212-E214 VanDerWaalsContact C-N 3.25Å; L212-E214 PolarHBondContact O-N 3.36Å; E214-F216 VanDerWaalsContact C-N 3.26Å; E214-F216 PolarHBondContact O-N 3.19Å; E214-W217 VanDerWaalsContact O-CB 3.26Å; E214-W217 WeakPolarHBondContact O-CB 3.45Å; E214-W217 PolarHBondContact O-N 3.13Å; E214-W217 VanDerWaalsContact O-N 3.14Å; E214-A218 PolarHBondContact O-N 3.21Å
215	V	89	Confident	87.7	Confident	47 Å²	47	38.6 Å²	38.6	29%	0.285	20%	0.198	S	C	.	.	H	α-helix	trans	-65.1	-33.9	171.5	-176.4	0	0	0	0	110.8	L212 I213 W217 A218 I219 F384	L212-V215 HydrophobicContact CD1-CG2 4.35Å; L212-V215 VanDerWaalsContact O-CB 3.29Å; L212-V215 WeakPolarHBondContact O-CB 3.41Å; L212-V215 PolarHBondContact O-N 2.97Å; L212-V215 VanDerWaalsContact O-N 3.11Å; I213-V215 PolarHBondContact O-N 3.31Å; I213-V215 VanDerWaalsContact O-N 3.17Å; V215-W217 PolarHBondContact O-N 2.86Å; V215-A218 PolarHBondContact O-N 3.35Å; V215-I219 HydrophobicContact CG1-CD1 4.05Å; V215-I219 HydrophobicContact CG1-CG1 4.42Å; V215-I219 VanDerWaalsContact O-CG1 3.26Å; V215-I219 WeakPolarHBondContact O-CG1 3.16Å; V215-I219 PolarHBondContact O-N 3.14Å; V215-F384 HydrophobicContact CG1-CD1 4.47Å; V215-F384 HydrophobicContact CG1-CE1 4.02Å
216	F	92.3	Very high	88.5	Confident	35 Å²	35	39.8 Å²	39.8	15%	0.154	20%	0.203	C	C	.	.	H	α-helix	trans	-66.3	-28.3	174.1	-72	-91.9	0	0	0	112.5	M95 I213 E214 G220	M95-F216 WeakPolarHBondContact CA-O 3.31Å; M95-F216 HydrophobicContact CB-CB 4.39Å; I213-F216 WeakPolarHBondContact O-CA 3Å; I213-F216 VanDerWaalsContact O-CB 3.29Å; I213-F216 WeakPolarHBondContact O-CB 3.25Å; I213-F216 PolarHBondContact O-N 2.82Å; E214-F216 VanDerWaalsContact C-N 3.26Å; E214-F216 PolarHBondContact O-N 3.19Å; F216-G220 PolarHBondContact O-N 2.9Å
217	W	92.5	Very high	89.2	Confident	18 Å²	18	36.5 Å²	36.5	7%	0.068	19%	0.192	C	C	.	.	H	α-helix	trans	-63.4	-51.3	171.6	-175.6	-81.9	0	0	0	110.7	W94 D97 A98 M101 E214 V215 I219 G220 T221 Y331 Y332	W94-W217 HydrophobicContact CD2-CE3 4.35Å; W94-W217 AromaticContact CE2-CE3 3.73Å; W94-W217 AromaticContact CZ2-CE3 3.96Å; W94-W217 HydrophobicContact CZ2-CE3 3.96Å; W94-W217 HydrophobicContact CZ2-CZ3 4.26Å; W94-W217 AromaticContact NE1-CE3 3.7Å; D97-W217 HydrophobicContact CB-CZ3 4.38Å; A98-W217 HydrophobicContact CB-CB 4.28Å; A98-W217 HydrophobicContact CB-CD2 3.52Å; A98-W217 HydrophobicContact CB-CE3 3.7Å; A98-W217 HydrophobicContact CB-CG 3.79Å; A98-W217 HydrophobicContact CB-CZ2 4.42Å; A98-W217 HydrophobicContact CB-CZ3 4.23Å; A98-W217 VanDerWaalsContact CB-O 3.3Å; A98-W217 WeakPolarHBondContact CB-O 3.34Å; M101-W217 HydrophobicContact CB-CH2 4.36Å; M101-W217 HydrophobicContact CB-CZ2 4.4Å; M101-W217 HydrophobicContact CG-CH2 3.9Å; M101-W217 HydrophobicContact CG-CZ2 4.39Å; E214-W217 VanDerWaalsContact O-CB 3.26Å; E214-W217 WeakPolarHBondContact O-CB 3.45Å; E214-W217 PolarHBondContact O-N 3.13Å; E214-W217 VanDerWaalsContact O-N 3.14Å; V215-W217 PolarHBondContact O-N 2.86Å; W217-I219 VanDerWaalsContact C-N 3.3Å; W217-I219 PolarHBondContact O-N 3.12Å; W217-G220 PolarHBondContact O-N 3.19Å; W217-T221 PolarHBondContact O-N 3.2Å; W217-T221 PolarHBondContact O-OG1 2.85Å; W217-Y331 HydrophobicContact CZ2-CE1 4.09Å; W217-Y331 AromaticContact NE1-CZ 3.69Å; W217-Y331 PolarHBondContact NE1-OH 3.5Å; W217-Y332 HydrophobicContact CH2-CE1 4.49Å; W217-Y332 HydrophobicContact CZ2-CE1 4.22Å
218	A	93.1	Very high	90.1	Very high	2 Å²	2	33.3 Å²	33.3	2%	0.017	17%	0.166	C	C	.	.	H	α-helix	trans	-62	-36.4	177.3	0	0	0	0	0	112.8	E214 V215 G220 T221 V222 E383 F384	E214-A218 PolarHBondContact O-N 3.21Å; V215-A218 PolarHBondContact O-N 3.35Å; A218-G220 VanDerWaalsContact C-N 3.35Å; A218-T221 WeakPolarHBondContact CA-OG1 3.42Å; A218-T221 PolarHBondContact O-OG1 3.21Å; A218-V222 WeakPolarHBondContact O-CB 3.47Å; A218-V222 WeakPolarHBondContact O-CG2 3.35Å; A218-V222 PolarHBondContact O-N 3.11Å; A218-V222 VanDerWaalsContact O-N 3.14Å; A218-E383 WeakPolarHBondContact CA-OE2 3.39Å; A218-E383 HydrophobicContact CB-CB 3.86Å; A218-F384 HydrophobicContact CB-CD1 4.18Å; A218-F384 HydrophobicContact CB-CD2 4.48Å; A218-F384 HydrophobicContact CB-CE1 3.88Å; A218-F384 HydrophobicContact CB-CE2 4.21Å; A218-F384 HydrophobicContact CB-CG 4.46Å; A218-F384 HydrophobicContact CB-CZ 3.9Å
219	I	95	Very high	90.7	Very high	65 Å²	65	26.9 Å²	26.9	33%	0.333	14%	0.14	S	C	.	.	H	α-helix	trans	-62.9	-43.7	172.6	-68.9	165.8	0	0	0	110.3	M95 V215 W217 F223 F384	M95-I219 HydrophobicContact SD-CG2 4.21Å; V215-I219 HydrophobicContact CG1-CD1 4.05Å; V215-I219 HydrophobicContact CG1-CG1 4.42Å; V215-I219 VanDerWaalsContact O-CG1 3.26Å; V215-I219 WeakPolarHBondContact O-CG1 3.16Å; V215-I219 PolarHBondContact O-N 3.14Å; W217-I219 VanDerWaalsContact C-N 3.3Å; W217-I219 PolarHBondContact O-N 3.12Å; I219-F223 WeakPolarHBondContact O-CB 3.5Å; I219-F223 PolarHBondContact O-N 2.96Å; I219-F384 HydrophobicContact CG1-CE1 3.99Å; I219-F384 HydrophobicContact CG1-CZ 3.83Å
220	G	95.6	Very high	91.1	Very high	0 Å²	0	33.5 Å²	33.5	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-63.5	-47.4	178.8	0	0	0	0	0	112.8	M99 F216 W217 A218 V222 F223 E224	M99-G220 WeakPolarHBondContact CG-O 3.28Å; F216-G220 PolarHBondContact O-N 2.9Å; W217-G220 PolarHBondContact O-N 3.19Å; A218-G220 VanDerWaalsContact C-N 3.35Å; G220-V222 PolarHBondContact O-N 3.36Å; G220-F223 PolarHBondContact O-N 3.33Å; G220-E224 WeakPolarHBondContact O-CB 3.44Å; G220-E224 PolarHBondContact O-N 3.28Å
221	T	95	Very high	91.8	Very high	2 Å²	2	31.5 Å²	31.5	1%	0.012	16%	0.158	C	C	.	.	H	α-helix	trans	-60.4	-44.4	178.6	55.6	0	0	0	0	111.9	A98 M102 W217 A218 V225 E383	A98-T221 HydrophobicContact CB-CG2 4.13Å; M102-T221 HydrophobicContact CE-CG2 3.89Å; W217-T221 PolarHBondContact O-N 3.2Å; W217-T221 PolarHBondContact O-OG1 2.85Å; A218-T221 WeakPolarHBondContact CA-OG1 3.42Å; A218-T221 PolarHBondContact O-OG1 3.21Å; T221-V225 WeakPolarHBondContact O-CG2 3.45Å; T221-V225 PolarHBondContact O-N 2.9Å; T221-E383 PolarHBondContact OG1-OE2 2.83Å
222	V	95.8	Very high	92.4	Very high	19 Å²	19	30.4 Å²	30.4	12%	0.115	15%	0.152	C	C	.	.	H	α-helix	trans	-69.8	-41.9	177.5	170.4	0	0	0	0	111.8	A218 G220 E224 V225 V226 L377 L381 F384	A218-V222 WeakPolarHBondContact O-CB 3.47Å; A218-V222 WeakPolarHBondContact O-CG2 3.35Å; A218-V222 PolarHBondContact O-N 3.11Å; A218-V222 VanDerWaalsContact O-N 3.14Å; G220-V222 PolarHBondContact O-N 3.36Å; V222-E224 VanDerWaalsContact C-N 3.31Å; V222-E224 PolarHBondContact O-N 3.16Å; V222-V225 PolarHBondContact O-N 3.21Å; V222-V226 HydrophobicContact CG1-CG2 4.23Å; V222-V226 VanDerWaalsContact O-CG2 3.31Å; V222-V226 WeakPolarHBondContact O-CG2 3.38Å; V222-V226 PolarHBondContact O-N 3.18Å; V222-L377 HydrophobicContact CG1-CD1 3.97Å; V222-L381 HydrophobicContact CG1-CD2 4.03Å; V222-L381 HydrophobicContact CG2-CD2 4.08Å; V222-L381 HydrophobicContact CG2-CG 4.33Å; V222-F384 HydrophobicContact CB-CE2 4.4Å; V222-F384 HydrophobicContact CG2-CE2 3.85Å
223	F	96.1	Very high	92.7	Very high	88 Å²	88	31 Å²	31	39%	0.386	16%	0.16	S	C	.	.	H	α-helix	trans	-61.8	-39.5	178.9	-174.5	-98.5	0	0	0	111.8	M95 M99 I219 G220 V226 L227	M95-F223 HydrophobicContact CE-CB 4.28Å; M95-F223 HydrophobicContact CE-CD1 3.8Å; M95-F223 HydrophobicContact CE-CE1 4.29Å; M95-F223 HydrophobicContact CE-CG 4Å; M99-F223 HydrophobicContact CE-CD1 3.54Å; M99-F223 HydrophobicContact CE-CE1 3.88Å; M99-F223 HydrophobicContact SD-CD1 3.67Å; M99-F223 HydrophobicContact SD-CE1 4.31Å; I219-F223 WeakPolarHBondContact O-CB 3.5Å; I219-F223 PolarHBondContact O-N 2.96Å; G220-F223 PolarHBondContact O-N 3.33Å; F223-V226 PolarHBondContact O-N 3.4Å; F223-L227 VanDerWaalsContact O-CB 3.31Å; F223-L227 WeakPolarHBondContact O-CB 3.3Å; F223-L227 PolarHBondContact O-N 3.48Å
224	E	96.5	Very high	92.9	Very high	0 Å²	0	35.1 Å²	35.1	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-62.2	-43.5	175.2	-175.4	58.5	-153.5	0	0	112.3	M99 M102 I103 G220 V222 L227 A228 S244	M99-E224 HydrophobicContact CB-CB 4.31Å; M99-E224 WeakPolarHBondContact CE-OE2 3.33Å; M99-E224 HydrophobicContact CG-CB 4.1Å; M102-E224 HydrophobicContact CB-CB 4.01Å; M102-E224 HydrophobicContact CB-CG 3.88Å; M102-E224 HydrophobicContact CG-CB 3.86Å; M102-E224 HydrophobicContact CG-CG 3.75Å; I103-E224 HydrophobicContact CB-CG 4.24Å; I103-E224 WeakPolarHBondContact CB-OE1 3.47Å; I103-E224 VanDerWaalsContact CD1-OE1 3.32Å; I103-E224 WeakPolarHBondContact CD1-OE1 3.32Å; I103-E224 VanDerWaalsContact CG1-OE1 3.29Å; I103-E224 WeakPolarHBondContact CG1-OE1 3.39Å; G220-E224 WeakPolarHBondContact O-CB 3.44Å; G220-E224 PolarHBondContact O-N 3.28Å; V222-E224 VanDerWaalsContact C-N 3.31Å; V222-E224 PolarHBondContact O-N 3.16Å; E224-L227 WeakPolarHBondContact O-CB 3.32Å; E224-L227 PolarHBondContact O-N 2.88Å; E224-A228 WeakPolarHBondContact O-CB 3.32Å; E224-A228 PolarHBondContact O-N 3.23Å; E224-S244 PolarHBondContact OE1-OG 3.38Å; E224-S244 VanDerWaalsContact OE2-CB 3.25Å; E224-S244 WeakPolarHBondContact OE2-CB 3.49Å; E224-S244 PolarHBondContact OE2-OG 3.28Å
225	V	95.2	Very high	93.3	Very high	0 Å²	0	38.4 Å²	38.4	0%	0	21%	0.206	C	C	.	.	H	α-helix	trans	-67.8	-42.3	178.1	178.1	0	0	0	0	111.5	M102 I106 T221 V222 L227 A228 V229 L376 L377 T380	M102-V225 HydrophobicContact CE-CG2 4.31Å; M102-V225 HydrophobicContact CG-CG2 4Å; M102-V225 HydrophobicContact SD-CG2 4.02Å; I106-V225 HydrophobicContact CD1-CG2 4.47Å; T221-V225 WeakPolarHBondContact O-CG2 3.45Å; T221-V225 PolarHBondContact O-N 2.9Å; V222-V225 PolarHBondContact O-N 3.21Å; V225-L227 VanDerWaalsContact C-N 3.27Å; V225-L227 PolarHBondContact O-N 3.4Å; V225-A228 WeakPolarHBondContact O-CB 3.37Å; V225-A228 PolarHBondContact O-N 3.35Å; V225-A228 VanDerWaalsContact O-N 3.14Å; V225-V229 WeakPolarHBondContact O-CG2 3.36Å; V225-V229 PolarHBondContact O-N 2.89Å; V225-L376 HydrophobicContact CG1-CB 4.11Å; V225-L376 HydrophobicContact CG1-CD2 4.06Å; V225-L376 HydrophobicContact CG1-CG 3.98Å; V225-L376 HydrophobicContact CG2-CD2 3.8Å; V225-L376 HydrophobicContact CG2-CG 3.81Å; V225-L377 HydrophobicContact CG1-CB 3.91Å; V225-L377 HydrophobicContact CG1-CD1 4.31Å; V225-T380 HydrophobicContact CG2-CG2 3.93Å
226	V	95.6	Very high	93.4	Very high	48 Å²	48	37.1 Å²	37.1	29%	0.291	20%	0.202	S	C	.	.	H	α-helix	trans	-58.9	-43	174.3	171.5	0	0	0	0	110.4	V222 F223 A228 V229 F230 L377	V222-V226 HydrophobicContact CG1-CG2 4.23Å; V222-V226 VanDerWaalsContact O-CG2 3.31Å; V222-V226 WeakPolarHBondContact O-CG2 3.38Å; V222-V226 PolarHBondContact O-N 3.18Å; F223-V226 PolarHBondContact O-N 3.4Å; V226-A228 VanDerWaalsContact C-N 3.34Å; V226-A228 PolarHBondContact O-N 2.83Å; V226-V229 PolarHBondContact O-N 3.16Å; V226-F230 HydrophobicContact CG1-CD2 4.1Å; V226-F230 HydrophobicContact CG1-CE2 3.8Å; V226-F230 WeakPolarHBondContact O-CD2 3.21Å; V226-F230 PolarHBondContact O-N 2.88Å; V226-L377 HydrophobicContact CG2-CD1 3.68Å
227	L	95.3	Very high	93.4	Very high	27 Å²	27	35.8 Å²	35.8	14%	0.141	20%	0.196	C	C	.	.	H	α-helix	trans	-61.8	-43.3	175.8	-172.8	65.5	0	0	0	111.1	F223 E224 V225 V229 F230 V231 L240 L243 S244	F223-L227 VanDerWaalsContact O-CB 3.31Å; F223-L227 WeakPolarHBondContact O-CB 3.3Å; F223-L227 PolarHBondContact O-N 3.48Å; E224-L227 WeakPolarHBondContact O-CB 3.32Å; E224-L227 PolarHBondContact O-N 2.88Å; V225-L227 VanDerWaalsContact C-N 3.27Å; V225-L227 PolarHBondContact O-N 3.4Å; L227-V229 PolarHBondContact O-N 3.14Å; L227-F230 PolarHBondContact O-N 3.07Å; L227-V231 HydrophobicContact CD1-CG2 3.67Å; L227-V231 HydrophobicContact CG-CG2 4.03Å; L227-V231 VanDerWaalsContact O-CB 3.25Å; L227-V231 WeakPolarHBondContact O-CB 3.29Å; L227-V231 WeakPolarHBondContact O-CG2 3.37Å; L227-V231 PolarHBondContact O-N 3.31Å; L227-L240 HydrophobicContact CB-CD1 4.24Å; L227-L240 HydrophobicContact CD2-CD1 3.9Å; L227-L240 HydrophobicContact CG-CD1 3.78Å; L227-L243 HydrophobicContact CD1-CB 4.03Å; L227-L243 HydrophobicContact CD1-CD1 4.2Å; L227-L243 HydrophobicContact CD2-CB 3.76Å; L227-L243 HydrophobicContact CG-CB 4.35Å; L227-S244 WeakPolarHBondContact CD2-OG 3.49Å
228	A	93.9	Very high	93.6	Very high	0 Å²	0	39.6 Å²	39.6	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-61.1	-41.8	176.8	0	0	0	0	0	112.9	I106 E224 V225 V226 F230 V231 M232 L240 Y373	I106-A228 HydrophobicContact CD1-CB 3.58Å; I106-A228 HydrophobicContact CG2-CB 4.27Å; E224-A228 WeakPolarHBondContact O-CB 3.32Å; E224-A228 PolarHBondContact O-N 3.23Å; V225-A228 WeakPolarHBondContact O-CB 3.37Å; V225-A228 PolarHBondContact O-N 3.35Å; V225-A228 VanDerWaalsContact O-N 3.14Å; V226-A228 VanDerWaalsContact C-N 3.34Å; V226-A228 PolarHBondContact O-N 2.83Å; A228-F230 VanDerWaalsContact C-N 3.26Å; A228-F230 PolarHBondContact O-N 3.44Å; A228-V231 PolarHBondContact O-N 3.37Å; A228-M232 HydrophobicContact CB-CG 4.06Å; A228-M232 WeakPolarHBondContact O-CB 3.46Å; A228-M232 WeakPolarHBondContact O-CG 3.49Å; A228-M232 PolarHBondContact O-N 3.06Å; A228-L240 HydrophobicContact CB-CD1 4.2Å; A228-L240 HydrophobicContact CB-CD2 4.3Å; A228-Y373 HydrophobicContact CB-CD1 4.1Å; A228-Y373 HydrophobicContact CB-CE1 3.89Å
229	V	93.2	Very high	93.7	Very high	24 Å²	24	45.7 Å²	45.7	15%	0.145	23%	0.233	C	C	.	.	H	α-helix	trans	-53.8	-42.7	176.4	171.8	0	0	0	0	111.6	V225 V226 L227 P233 Y373 M374	V225-V229 WeakPolarHBondContact O-CG2 3.36Å; V225-V229 PolarHBondContact O-N 2.89Å; V226-V229 PolarHBondContact O-N 3.16Å; L227-V229 PolarHBondContact O-N 3.14Å; V229-P233 VanDerWaalsContact O-CD 3.24Å; V229-P233 WeakPolarHBondContact O-CD 3.25Å; V229-P233 WeakPolarHBondContact O-CG 3.38Å; V229-Y373 HydrophobicContact CG2-CG 4.46Å; V229-M374 HydrophobicContact CG1-CE 3.95Å
230	F	92.6	Very high	93.8	Very high	150 Å²	150	42.6 Å²	42.6	66%	0.658	22%	0.217	S	C	*	.	H	α-helix	trans	-86.5	-35.6	-176.6	-67.8	-65.9	0	0	0	113.6	V226 L227 A228 S234	V226-F230 HydrophobicContact CG1-CD2 4.1Å; V226-F230 HydrophobicContact CG1-CE2 3.8Å; V226-F230 WeakPolarHBondContact O-CD2 3.21Å; V226-F230 PolarHBondContact O-N 2.88Å; L227-F230 PolarHBondContact O-N 3.07Å; A228-F230 VanDerWaalsContact C-N 3.26Å; A228-F230 PolarHBondContact O-N 3.44Å; F230-S234 PolarHBondContact O-OG 3.02Å
231	V	94.4	Very high	93.8	Very high	8 Å²	8	42.6 Å²	42.6	5%	0.048	22%	0.217	C	C	.	.	H	α-helix	trans	-90.6	-38.6	-169.6	177.7	0	0	0	0	111.9	L227 A228 S234 L235 G236 W239 L240 L243	L227-V231 HydrophobicContact CD1-CG2 3.67Å; L227-V231 HydrophobicContact CG-CG2 4.03Å; L227-V231 VanDerWaalsContact O-CB 3.25Å; L227-V231 WeakPolarHBondContact O-CB 3.29Å; L227-V231 WeakPolarHBondContact O-CG2 3.37Å; L227-V231 PolarHBondContact O-N 3.31Å; A228-V231 PolarHBondContact O-N 3.37Å; V231-S234 PolarHBondContact O-N 3.27Å; V231-S234 PolarHBondContact O-OG 3.37Å; V231-L235 HydrophobicContact CG1-CB 4.06Å; V231-L235 HydrophobicContact CG1-CD1 4.42Å; V231-L235 PolarHBondContact O-N 2.89Å; V231-G236 PolarHBondContact O-N 2.96Å; V231-W239 HydrophobicContact CG1-CB 3.82Å; V231-L240 HydrophobicContact CG1-CB 4.21Å; V231-L243 HydrophobicContact CG1-CD1 4.17Å; V231-L243 HydrophobicContact CG2-CD1 3.59Å
232	M	91.2	Very high	93.8	Very high	19 Å²	19	44.8 Å²	44.8	9%	0.094	23%	0.228	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63	-44	-174.8	-70.7	-67.5	-68.6	0	0	113.4	I106 Q110 A228 S234 G236 W237 L240 Y373	I106-M232 HydrophobicContact CG2-CE 4.41Å; I106-M232 HydrophobicContact CG2-CG 4.45Å; Q110-M232 HydrophobicContact CB-CE 4.13Å; Q110-M232 HydrophobicContact CG-CE 3.86Å; A228-M232 HydrophobicContact CB-CG 4.06Å; A228-M232 WeakPolarHBondContact O-CB 3.46Å; A228-M232 WeakPolarHBondContact O-CG 3.49Å; A228-M232 PolarHBondContact O-N 3.06Å; M232-S234 VanDerWaalsContact C-N 3.32Å; M232-S234 PolarHBondContact O-N 3.5Å; M232-G236 PolarHBondContact O-N 2.93Å; M232-W237 HydrophobicContact CE-CB 4.41Å; M232-W237 HydrophobicContact SD-CB 4.18Å; M232-L240 HydrophobicContact CG-CD2 4.15Å; M232-L240 HydrophobicContact SD-CB 4.31Å; M232-L240 HydrophobicContact SD-CD2 3.76Å; M232-Y373 HydrophobicContact CB-CE2 4.13Å; M232-Y373 WeakPolarHBondContact CB-OH 3.21Å; M232-Y373 WeakPolarHBondContact CE-OH 3.21Å; M232-Y373 HydrophobicContact CG-CE1 4.3Å; M232-Y373 WeakPolarHBondContact CG-OH 3.38Å
233	P	87.5	Confident	93.8	Very high	76 Å²	76	46.5 Å²	46.5	49%	0.494	24%	0.237	S	C	.	.	T	Hydrogen-bonded Turn	trans	-68.1	-28.1	-179.7	-22.2	34.7	0	0	0	114.2	V229	V229-P233 VanDerWaalsContact O-CD 3.24Å; V229-P233 WeakPolarHBondContact O-CD 3.25Å; V229-P233 WeakPolarHBondContact O-CG 3.38Å
234	S	88.8	Confident	93.8	Very high	86 Å²	86	42.5 Å²	42.5	60%	0.601	22%	0.219	S	C	*	.	T	Hydrogen-bonded Turn	trans	-104.1	-46.6	-169.9	58.4	0	0	0	0	113.6	F230 V231 M232	F230-S234 PolarHBondContact O-OG 3.02Å; V231-S234 PolarHBondContact O-N 3.27Å; V231-S234 PolarHBondContact O-OG 3.37Å; M232-S234 VanDerWaalsContact C-N 3.32Å; M232-S234 PolarHBondContact O-N 3.5Å
235	L	90.3	Very high	93.7	Very high	93 Å²	93	42.6 Å²	42.6	49%	0.487	22%	0.22	S	C	.	.	T	Hydrogen-bonded Turn	trans	-114.7	-22.4	-169	-64.7	174.7	0	0	0	112.7	V231 W239	V231-L235 HydrophobicContact CG1-CB 4.06Å; V231-L235 HydrophobicContact CG1-CD1 4.42Å; V231-L235 PolarHBondContact O-N 2.89Å; L235-W239 HydrophobicContact CB-CB 3.7Å; L235-W239 HydrophobicContact CB-CG 3.73Å; L235-W239 HydrophobicContact CD1-CB 4.21Å; L235-W239 HydrophobicContact CD1-CD2 4.46Å; L235-W239 HydrophobicContact CD1-CG 4.19Å; L235-W239 HydrophobicContact CG-CG 4.39Å
236	G	91.3	Very high	93.7	Very high	19 Å²	19	45.4 Å²	45.4	20%	0.196	24%	0.237	C	C	.	.			trans	78.8	-177.2	178.2	0	0	0	0	0	114.9	V231 M232 R238 W239 L240	V231-G236 PolarHBondContact O-N 2.96Å; M232-G236 PolarHBondContact O-N 2.93Å; G236-R238 VanDerWaalsContact C-N 3.31Å; G236-R238 PolarHBondContact O-N 3.45Å; G236-W239 PolarHBondContact O-N 3.33Å; G236-L240 PolarHBondContact O-N 3.42Å
237	W	93.6	Very high	93.6	Very high	8 Å²	8	43.3 Å²	43.3	3%	0.03	23%	0.225	C	C	.	.	H	α-helix	trans	-64.7	-26.5	-167.7	66.3	-92.6	0	0	0	115.5	L107 Q110 L111 W115 I176 M232 L240 L241	L107-W237 HydrophobicContact CD1-CB 3.86Å; L107-W237 HydrophobicContact CD1-CD2 4.13Å; L107-W237 HydrophobicContact CD1-CE3 3.77Å; L107-W237 HydrophobicContact CD1-CG 4.21Å; Q110-W237 HydrophobicContact CG-CB 4.06Å; Q110-W237 HydrophobicContact CG-CG 4.18Å; L111-W237 HydrophobicContact CD2-CD2 4.04Å; L111-W237 HydrophobicContact CD2-CE3 4.42Å; L111-W237 HydrophobicContact CD2-CH2 4.27Å; L111-W237 HydrophobicContact CD2-CZ2 3.85Å; W115-W237 HydrophobicContact CH2-CH2 4.33Å; W115-W237 HydrophobicContact CH2-CZ2 4.44Å; W115-W237 HydrophobicContact CZ2-CH2 4.45Å; W115-W237 HydrophobicContact CZ2-CZ2 4.22Å; I176-W237 HydrophobicContact CD1-CH2 4.28Å; I176-W237 HydrophobicContact CD1-CZ3 3.87Å; M232-W237 HydrophobicContact CE-CB 4.41Å; M232-W237 HydrophobicContact SD-CB 4.18Å; W237-L240 WeakPolarHBondContact O-CB 3.15Å; W237-L240 PolarHBondContact O-N 3.46Å; W237-L241 HydrophobicContact CE3-CD1 3.53Å; W237-L241 HydrophobicContact CE3-CG 4.38Å; W237-L241 HydrophobicContact CZ3-CD1 3.51Å; W237-L241 WeakPolarHBondContact O-CG 3.19Å; W237-L241 PolarHBondContact O-N 2.88Å; W237-L241 VanDerWaalsContact O-N 3.1Å
238	R	95.6	Very high	93.5	Very high	97 Å²	97	42.2 Å²	42.2	37%	0.366	22%	0.219	S	C	.	.	H	α-helix	trans	-65.8	-42.2	179.3	-65.7	-173.2	168.8	92.2	1.5	111.2	A168 G236 I242	A168-R238 HydrophobicContact CB-CB 4.48Å; A168-R238 VanDerWaalsContact CB-O 3.3Å; A168-R238 WeakPolarHBondContact CB-O 3.39Å; A168-R238 VanDerWaalsContact O-CD 3.26Å; A168-R238 WeakPolarHBondContact O-CD 3.49Å; A168-R238 VanDerWaalsContact O-CG 3.26Å; A168-R238 WeakPolarHBondContact O-CG 3.35Å; G236-R238 VanDerWaalsContact C-N 3.31Å; G236-R238 PolarHBondContact O-N 3.45Å; R238-I242 WeakPolarHBondContact O-CG1 3.29Å; R238-I242 PolarHBondContact O-N 3.05Å
239	W	95.8	Very high	93.5	Very high	130 Å²	130	46.6 Å²	46.6	49%	0.492	24%	0.242	S	C	.	.	H	α-helix	trans	-72.7	-32.8	176.6	-75	96.9	0	0	0	112.1	V231 L235 G236 I242 L243	V231-W239 HydrophobicContact CG1-CB 3.82Å; L235-W239 HydrophobicContact CB-CB 3.7Å; L235-W239 HydrophobicContact CB-CG 3.73Å; L235-W239 HydrophobicContact CD1-CB 4.21Å; L235-W239 HydrophobicContact CD1-CD2 4.46Å; L235-W239 HydrophobicContact CD1-CG 4.19Å; L235-W239 HydrophobicContact CG-CG 4.39Å; G236-W239 PolarHBondContact O-N 3.33Å; W239-I242 PolarHBondContact O-N 3.43Å; W239-L243 WeakPolarHBondContact O-CB 3.33Å; W239-L243 VanDerWaalsContact O-CG 3.29Å; W239-L243 WeakPolarHBondContact O-CG 3.31Å; W239-L243 PolarHBondContact O-N 3.47Å
240	L	95.8	Very high	93.6	Very high	1 Å²	1	49.7 Å²	49.7	1%	0.005	26%	0.257	C	S	.	.	H	α-helix	trans	-55.6	-53.2	171.8	-174	64.6	0	0	0	110	I103 I106 L227 A228 V231 M232 G236 W237 I242 L243 S244	I103-L240 HydrophobicContact CD1-CD2 4.25Å; I103-L240 HydrophobicContact CD1-CG 3.98Å; I103-L240 HydrophobicContact CG1-CD2 4.1Å; I103-L240 HydrophobicContact CG1-CG 4.36Å; I106-L240 HydrophobicContact CG2-CD2 4.06Å; L227-L240 HydrophobicContact CB-CD1 4.24Å; L227-L240 HydrophobicContact CD2-CD1 3.9Å; L227-L240 HydrophobicContact CG-CD1 3.78Å; A228-L240 HydrophobicContact CB-CD1 4.2Å; A228-L240 HydrophobicContact CB-CD2 4.3Å; V231-L240 HydrophobicContact CG1-CB 4.21Å; M232-L240 HydrophobicContact CG-CD2 4.15Å; M232-L240 HydrophobicContact SD-CB 4.31Å; M232-L240 HydrophobicContact SD-CD2 3.76Å; G236-L240 PolarHBondContact O-N 3.42Å; W237-L240 WeakPolarHBondContact O-CB 3.15Å; W237-L240 PolarHBondContact O-N 3.46Å; L240-I242 VanDerWaalsContact C-N 3.29Å; L240-I242 PolarHBondContact O-N 3.39Å; L240-L243 PolarHBondContact O-N 2.83Å; L240-L243 VanDerWaalsContact O-N 3.15Å; L240-S244 WeakPolarHBondContact O-CB 3.43Å; L240-S244 PolarHBondContact O-N 3.11Å; L240-S244 PolarHBondContact O-OG 3.05Å
241	L	95.8	Very high	93.6	Very high	0 Å²	0	42.6 Å²	42.6	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-54.5	-39.4	177.3	-72.8	174.5	0	0	0	114.3	I103 L107 A168 W237	I103-L241 HydrophobicContact CD1-CD2 3.63Å; I103-L241 HydrophobicContact CD1-CG 4.31Å; I103-L241 HydrophobicContact CG1-CD2 4.48Å; L107-L241 HydrophobicContact CD2-CD2 4.19Å; A168-L241 HydrophobicContact CB-CB 4Å; A168-L241 HydrophobicContact CB-CD1 4.38Å; W237-L241 HydrophobicContact CE3-CD1 3.53Å; W237-L241 HydrophobicContact CE3-CG 4.38Å; W237-L241 HydrophobicContact CZ3-CD1 3.51Å; W237-L241 WeakPolarHBondContact O-CG 3.19Å; W237-L241 PolarHBondContact O-N 2.88Å; W237-L241 VanDerWaalsContact O-N 3.1Å
242	I	96.4	Very high	93.5	Very high	48 Å²	48	42.9 Å²	42.9	25%	0.246	23%	0.229	C	C	.	.	H	α-helix	trans	-71.7	-45	179.4	-65.3	171.5	0	0	0	110.7	A168 F169 R238 W239 L240 A245	A168-I242 HydrophobicContact CB-CD1 3.86Å; A168-I242 HydrophobicContact CB-CG1 3.51Å; F169-I242 HydrophobicContact CZ-CD1 4.43Å; R238-I242 WeakPolarHBondContact O-CG1 3.29Å; R238-I242 PolarHBondContact O-N 3.05Å; W239-I242 PolarHBondContact O-N 3.43Å; L240-I242 VanDerWaalsContact C-N 3.29Å; L240-I242 PolarHBondContact O-N 3.39Å; I242-A245 WeakPolarHBondContact O-CB 3.44Å; I242-A245 PolarHBondContact O-N 3.32Å
243	L	96	Very high	93.6	Very high	55 Å²	55	46.5 Å²	46.5	29%	0.288	25%	0.252	S	S	.	.	H	α-helix	trans	-72.6	-31.9	-177.1	-67.9	172.1	0	0	0	111.8	L227 V231 W239 L240 A245 V246	L227-L243 HydrophobicContact CD1-CB 4.03Å; L227-L243 HydrophobicContact CD1-CD1 4.2Å; L227-L243 HydrophobicContact CD2-CB 3.76Å; L227-L243 HydrophobicContact CG-CB 4.35Å; V231-L243 HydrophobicContact CG1-CD1 4.17Å; V231-L243 HydrophobicContact CG2-CD1 3.59Å; W239-L243 WeakPolarHBondContact O-CB 3.33Å; W239-L243 VanDerWaalsContact O-CG 3.29Å; W239-L243 WeakPolarHBondContact O-CG 3.31Å; W239-L243 PolarHBondContact O-N 3.47Å; L240-L243 PolarHBondContact O-N 2.83Å; L240-L243 VanDerWaalsContact O-N 3.15Å; L243-A245 PolarHBondContact O-N 3.43Å; L243-V246 VanDerWaalsContact O-CB 3.27Å; L243-V246 WeakPolarHBondContact O-CB 3.31Å; L243-V246 WeakPolarHBondContact O-CG2 3.48Å; L243-V246 PolarHBondContact O-N 3.1Å; L243-V246 VanDerWaalsContact O-N 3.12Å
244	S	95.4	Very high	93.9	Very high	3 Å²	3	47 Å²	47	2%	0.021	25%	0.25	C	S	.	.	H	α-helix	trans	-66.3	-20.2	173.9	-57.1	0	0	0	0	112.8	E224 L227 L240 V246 P247	E224-S244 PolarHBondContact OE1-OG 3.38Å; E224-S244 VanDerWaalsContact OE2-CB 3.25Å; E224-S244 WeakPolarHBondContact OE2-CB 3.49Å; E224-S244 PolarHBondContact OE2-OG 3.28Å; L227-S244 WeakPolarHBondContact CD2-OG 3.49Å; L240-S244 WeakPolarHBondContact O-CB 3.43Å; L240-S244 PolarHBondContact O-N 3.11Å; L240-S244 PolarHBondContact O-OG 3.05Å; S244-V246 VanDerWaalsContact C-N 3.27Å; S244-V246 PolarHBondContact O-N 3.02Å; S244-P247 WeakPolarHBondContact O-CD 3.4Å
245	A	94.8	Very high	93.9	Very high	2 Å²	2	43 Å²	43	2%	0.017	22%	0.222	C	C	.	.	T	Hydrogen-bonded Turn	trans	-79	-5	174.9	0	0	0	0	0	113.9	L161 I165 I242 L243 L248 L249	L161-A245 HydrophobicContact CD1-CB 3.9Å; I165-A245 HydrophobicContact CD1-CB 4.35Å; I165-A245 HydrophobicContact CG1-CB 3.81Å; I242-A245 WeakPolarHBondContact O-CB 3.44Å; I242-A245 PolarHBondContact O-N 3.32Å; L243-A245 PolarHBondContact O-N 3.43Å; A245-L248 WeakPolarHBondContact O-CB 3.43Å; A245-L248 PolarHBondContact O-N 3.07Å; A245-L249 PolarHBondContact O-N 3.5Å
246	V	94	Very high	93.8	Very high	60 Å²	60	45.7 Å²	45.7	36%	0.364	23%	0.23	S	C	.	.	H	α-helix	trans	-58.6	-44.7	-176.9	168.8	0	0	0	0	113.3	L243 S244 L248 L249 L250	L243-V246 VanDerWaalsContact O-CB 3.27Å; L243-V246 WeakPolarHBondContact O-CB 3.31Å; L243-V246 WeakPolarHBondContact O-CG2 3.48Å; L243-V246 PolarHBondContact O-N 3.1Å; L243-V246 VanDerWaalsContact O-N 3.12Å; S244-V246 VanDerWaalsContact C-N 3.27Å; S244-V246 PolarHBondContact O-N 3.02Å; V246-L248 VanDerWaalsContact C-N 3.3Å; V246-L248 PolarHBondContact O-N 3.29Å; V246-L249 WeakPolarHBondContact O-CB 3.49Å; V246-L249 PolarHBondContact O-N 2.94Å; V246-L249 VanDerWaalsContact O-N 3.14Å; V246-L250 HydrophobicContact CG1-CD1 4.12Å; V246-L250 HydrophobicContact CG1-CG 4.35Å; V246-L250 WeakPolarHBondContact O-CG 3.49Å; V246-L250 PolarHBondContact O-N 3.1Å
247	P	93.1	Very high	93.8	Very high	4 Å²	4	48.5 Å²	48.5	3%	0.026	24%	0.235	C	C	.	.	H	α-helix	trans	-64.8	-33.4	177.7	-23.3	36.3	0	0	0	113.2	M95 A96 M99 S244 L250 F251	M95-P247 HydrophobicContact CE-CB 4.21Å; M95-P247 HydrophobicContact CE-CG 3.6Å; A96-P247 HydrophobicContact CB-CB 4.31Å; M99-P247 HydrophobicContact CE-CG 4.27Å; M99-P247 HydrophobicContact SD-CG 3.6Å; S244-P247 WeakPolarHBondContact O-CD 3.4Å; P247-L250 PolarHBondContact O-N 2.83Å; P247-F251 WeakPolarHBondContact O-CB 3.3Å; P247-F251 PolarHBondContact O-N 2.93Å
248	L	93.8	Very high	93.6	Very high	3 Å²	3	48.2 Å²	48.2	2%	0.016	23%	0.234	C	C	.	.	H	α-helix	trans	-66.1	-39.5	172.8	-65.9	169.4	0	0	0	111.1	A96 V157 T160 L161 A245 V246 F251 A252	A96-L248 HydrophobicContact CB-CD1 4.45Å; A96-L248 HydrophobicContact CB-CD2 3.35Å; A96-L248 HydrophobicContact CB-CG 3.56Å; V157-L248 HydrophobicContact CG1-CB 4.32Å; V157-L248 HydrophobicContact CG1-CD2 3.76Å; V157-L248 HydrophobicContact CG2-CD2 4.5Å; T160-L248 HydrophobicContact CG2-CD1 3.72Å; L161-L248 HydrophobicContact CB-CB 4.14Å; L161-L248 HydrophobicContact CD1-CB 4Å; A245-L248 WeakPolarHBondContact O-CB 3.43Å; A245-L248 PolarHBondContact O-N 3.07Å; V246-L248 VanDerWaalsContact C-N 3.3Å; V246-L248 PolarHBondContact O-N 3.29Å; L248-F251 PolarHBondContact O-N 3.36Å; L248-A252 WeakPolarHBondContact O-CB 3.49Å; L248-A252 PolarHBondContact O-N 2.69Å
249	L	94.4	Very high	93.4	Very high	93 Å²	93	44 Å²	44	49%	0.487	22%	0.219	S	C	.	.	H	α-helix	trans	-64.5	-45.5	174.7	-176.9	67.1	0	0	0	111.3	L161 A245 V246 F251 A252 V253	L161-L249 HydrophobicContact CD1-CB 4.24Å; L161-L249 HydrophobicContact CD2-CB 4.48Å; L161-L249 HydrophobicContact CD2-CD1 4.13Å; A245-L249 PolarHBondContact O-N 3.5Å; V246-L249 WeakPolarHBondContact O-CB 3.49Å; V246-L249 PolarHBondContact O-N 2.94Å; V246-L249 VanDerWaalsContact O-N 3.14Å; L249-F251 VanDerWaalsContact C-N 3.33Å; L249-F251 PolarHBondContact O-N 3.36Å; L249-A252 PolarHBondContact O-N 3.45Å; L249-V253 WeakPolarHBondContact O-CG2 3.36Å; L249-V253 PolarHBondContact O-N 3.32Å
250	L	94.5	Very high	93.2	Very high	88 Å²	88	39 Å²	39	46%	0.461	20%	0.202	S	C	.	.	H	α-helix	trans	-59.3	-45.3	174.8	-71	173.7	0	0	0	111	V246 P247 A252 V253 L254	V246-L250 HydrophobicContact CG1-CD1 4.12Å; V246-L250 HydrophobicContact CG1-CG 4.35Å; V246-L250 WeakPolarHBondContact O-CG 3.49Å; V246-L250 PolarHBondContact O-N 3.1Å; P247-L250 PolarHBondContact O-N 2.83Å; L250-A252 PolarHBondContact O-N 3.18Å; L250-V253 PolarHBondContact O-N 3.19Å; L250-L254 WeakPolarHBondContact O-CB 3.32Å; L250-L254 VanDerWaalsContact O-CG 3.25Å; L250-L254 WeakPolarHBondContact O-CG 3.5Å; L250-L254 PolarHBondContact O-N 2.83Å
251	F	93.5	Very high	92.8	Very high	1 Å²	1	39.1 Å²	39.1	0%	0.004	20%	0.202	C	C	.	.	H	α-helix	trans	-59.8	-46.7	174	-177.8	-85.3	0	0	0	111.7	L89 L92 A93 L153 V157 P247 L248 L249 V253 L254 C255 L258	L89-F251 HydrophobicContact CD1-CD2 3.71Å; L89-F251 HydrophobicContact CD1-CE2 3.91Å; L89-F251 HydrophobicContact CD1-CG 4.46Å; L89-F251 HydrophobicContact CG-CD2 4.2Å; L89-F251 HydrophobicContact CG-CE2 3.91Å; L89-F251 WeakPolarHBondContact O-CD2 3.48Å; L89-F251 VanDerWaalsContact O-CE2 3.24Å; L89-F251 WeakPolarHBondContact O-CE2 3.34Å; L92-F251 HydrophobicContact CB-CB 4.5Å; L92-F251 HydrophobicContact CB-CD2 4.44Å; A93-F251 HydrophobicContact CB-CD2 3.96Å; A93-F251 HydrophobicContact CB-CE2 3.94Å; A93-F251 HydrophobicContact CB-CZ 4.49Å; L153-F251 HydrophobicContact CD2-CE2 4.27Å; L153-F251 HydrophobicContact CD2-CZ 3.62Å; L153-F251 HydrophobicContact CG-CE1 4.26Å; L153-F251 HydrophobicContact CG-CZ 3.78Å; V157-F251 HydrophobicContact CB-CD1 3.88Å; V157-F251 HydrophobicContact CB-CE1 4.03Å; V157-F251 HydrophobicContact CG1-CB 4.34Å; V157-F251 HydrophobicContact CG1-CD1 3.45Å; V157-F251 VanDerWaalsContact CG1-CD1 3.45Å; V157-F251 HydrophobicContact CG1-CE1 4.13Å; V157-F251 HydrophobicContact CG1-CG 4.18Å; V157-F251 HydrophobicContact CG2-CD1 3.88Å; V157-F251 HydrophobicContact CG2-CE1 3.82Å; P247-F251 WeakPolarHBondContact O-CB 3.3Å; P247-F251 PolarHBondContact O-N 2.93Å; L248-F251 PolarHBondContact O-N 3.36Å; L249-F251 VanDerWaalsContact C-N 3.33Å; L249-F251 PolarHBondContact O-N 3.36Å; F251-V253 VanDerWaalsContact C-N 3.26Å; F251-V253 PolarHBondContact O-N 3.19Å; F251-L254 CarbonylContact O-C 3.58Å; F251-L254 PolarHBondContact O-N 3.37Å; F251-L254 VanDerWaalsContact O-N 3.1Å; F251-C255 HydrophobicContact CD1-CB 4.15Å; F251-C255 HydrophobicContact CE1-CB 3.82Å; F251-C255 HydrophobicContact CZ-CB 4.3Å; F251-C255 VanDerWaalsContact O-CB 3.25Å; F251-C255 WeakPolarHBondContact O-CB 3.37Å; F251-C255 PolarHBondContact O-N 2.91Å; F251-L258 HydrophobicContact CZ-CD2 4.36Å
252	A	92.4	Very high	92.4	Very high	14 Å²	14	39.3 Å²	39.3	12%	0.116	20%	0.203	C	C	.	.	H	α-helix	trans	-59.5	-36	-179.8	0	0	0	0	0	112.5	L158 L161 L248 L249 L250 C255	L158-A252 HydrophobicContact CD2-CB 3.71Å; L161-A252 HydrophobicContact CD2-CB 4.13Å; L248-A252 WeakPolarHBondContact O-CB 3.49Å; L248-A252 PolarHBondContact O-N 2.69Å; L249-A252 PolarHBondContact O-N 3.45Å; L250-A252 PolarHBondContact O-N 3.18Å; A252-C255 PolarHBondContact O-SG 3.36Å
253	V	93.4	Very high	91.9	Very high	95 Å²	95	41.4 Å²	41.4	58%	0.576	21%	0.208	S	C	*	.	H	α-helix	trans	-73.2	-40.1	174.3	175	0	0	0	0	111.5	L249 L250 F251 F256	L249-V253 WeakPolarHBondContact O-CG2 3.36Å; L249-V253 PolarHBondContact O-N 3.32Å; L250-V253 PolarHBondContact O-N 3.19Å; F251-V253 VanDerWaalsContact C-N 3.26Å; F251-V253 PolarHBondContact O-N 3.19Å; V253-F256 VanDerWaalsContact O-CD2 3.29Å; V253-F256 WeakPolarHBondContact O-CD2 3.44Å
254	L	92.6	Very high	91.4	Very high	88 Å²	88	41.1 Å²	41.1	46%	0.461	20%	0.204	S	C	.	.	H	α-helix	trans	-82.3	-16.7	-177.1	-63.8	174.2	0	0	0	113.6	L89 L92 L250 F251 F256 W257	L89-L254 HydrophobicContact CD1-CB 3.47Å; L89-L254 VanDerWaalsContact CD1-CB 3.47Å; L89-L254 HydrophobicContact CD1-CD1 4.42Å; L92-L254 HydrophobicContact CD1-CD1 4.03Å; L250-L254 WeakPolarHBondContact O-CB 3.32Å; L250-L254 VanDerWaalsContact O-CG 3.25Å; L250-L254 WeakPolarHBondContact O-CG 3.5Å; L250-L254 PolarHBondContact O-N 2.83Å; F251-L254 CarbonylContact O-C 3.58Å; F251-L254 PolarHBondContact O-N 3.37Å; F251-L254 VanDerWaalsContact O-N 3.1Å; L254-F256 PolarHBondContact O-N 2.87Å; L254-W257 PolarHBondContact O-N 2.91Å; L254-W257 VanDerWaalsContact O-N 3.09Å
255	C	89.9	Confident	91.1	Very high	2 Å²	2	41.4 Å²	41.4	1%	0.014	21%	0.205	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65.4	-14.2	-175.3	77.5	0	0	0	0	113.9	F251 A252 W257 L258	F251-C255 HydrophobicContact CD1-CB 4.15Å; F251-C255 HydrophobicContact CE1-CB 3.82Å; F251-C255 HydrophobicContact CZ-CB 4.3Å; F251-C255 VanDerWaalsContact O-CB 3.25Å; F251-C255 WeakPolarHBondContact O-CB 3.37Å; F251-C255 PolarHBondContact O-N 2.91Å; A252-C255 PolarHBondContact O-SG 3.36Å; C255-W257 PolarHBondContact O-N 3.13Å; C255-L258 VanDerWaalsContact O-CB 3.24Å; C255-L258 WeakPolarHBondContact O-CB 3.34Å; C255-L258 PolarHBondContact O-N 2.91Å
256	F	87.5	Confident	90.7	Very high	148 Å²	148	41.6 Å²	41.6	65%	0.649	21%	0.206	S	C	*	.	T	Hydrogen-bonded Turn	trans	-63.4	-32.7	173.1	-66.1	-70.8	0	0	0	112.2	V253 L254 L258	V253-F256 VanDerWaalsContact O-CD2 3.29Å; V253-F256 WeakPolarHBondContact O-CD2 3.44Å; L254-F256 PolarHBondContact O-N 2.87Å; F256-L258 VanDerWaalsContact C-N 3.32Å
257	W	90.6	Very high	90.2	Very high	79 Å²	79	42.7 Å²	42.7	30%	0.299	21%	0.21	S	C	.	.	S	Bend	trans	-73	-25.1	177.6	-180	87.5	0	0	0	113.2	F82 K85 L89 L254 C255 P259 R280	F82-W257 HydrophobicContact CD2-CH2 4.01Å; F82-W257 HydrophobicContact CD2-CZ2 4.16Å; F82-W257 AromaticContact CE2-CH2 3.99Å; F82-W257 HydrophobicContact CE2-CH2 3.99Å; F82-W257 HydrophobicContact CE2-CZ2 4.27Å; K85-W257 HydrophobicContact CB-CH2 3.56Å; K85-W257 HydrophobicContact CB-CZ2 4.06Å; K85-W257 HydrophobicContact CB-CZ3 4.05Å; K85-W257 HydrophobicContact CD-CH2 4.06Å; K85-W257 HydrophobicContact CD-CZ2 3.69Å; L89-W257 HydrophobicContact CD2-CE3 4.02Å; L254-W257 PolarHBondContact O-N 2.91Å; L254-W257 VanDerWaalsContact O-N 3.09Å; C255-W257 PolarHBondContact O-N 3.13Å; W257-P259 WeakPolarHBondContact O-CD 3.2Å; W257-R280 VanDerWaalsContact CD1-NH2 3.26Å; W257-R280 PolarHBondContact O-NH1 3.03Å; W257-R280 PolarHBondContact O-NH2 3.25Å
258	L	90.4	Very high	89.8	Confident	1 Å²	1	45.1 Å²	45.1	1%	0.005	23%	0.226	C	C	.	.	P	Polyproline II helix	trans	-57.7	120.8	-175.3	-168.6	64.3	0	0	0	110.2	L86 L89 K150 L153 L196 F251 C255 F256	L86-L258 HydrophobicContact CD1-CD1 3.35Å; L89-L258 HydrophobicContact CD2-CB 3.93Å; L89-L258 HydrophobicContact CD2-CD1 3.78Å; L89-L258 HydrophobicContact CD2-CG 4.37Å; L89-L258 HydrophobicContact CG-CD1 4.48Å; K150-L258 HydrophobicContact CB-CD2 4.43Å; K150-L258 WeakPolarHBondContact CD-O 3.41Å; K150-L258 WeakPolarHBondContact CE-O 3.25Å; K150-L258 HydrophobicContact CG-CB 4.35Å; K150-L258 HydrophobicContact CG-CD2 4Å; K150-L258 HydrophobicContact CG-CG 4.18Å; K150-L258 PolarHBondContact NZ-O 3.29Å; L153-L258 HydrophobicContact CD2-CD2 4.12Å; L196-L258 HydrophobicContact CD2-CD1 3.84Å; L196-L258 HydrophobicContact CD2-CD2 3.79Å; L196-L258 HydrophobicContact CD2-CG 3.97Å; F251-L258 HydrophobicContact CZ-CD2 4.36Å; C255-L258 VanDerWaalsContact O-CB 3.24Å; C255-L258 WeakPolarHBondContact O-CB 3.34Å; C255-L258 PolarHBondContact O-N 2.91Å; F256-L258 VanDerWaalsContact C-N 3.32Å
259	P	90.6	Very high	89.3	Confident	8 Å²	8	47.7 Å²	47.7	5%	0.052	25%	0.254	C	S	.	.	P	Polyproline II helix	trans	-78.6	158.5	172.8	27.2	-25.4	0	0	0	111.3	F82 F200 W257 T277	F82-P259 HydrophobicContact CE2-CG 3.85Å; F82-P259 HydrophobicContact CZ-CG 3.5Å; F82-P259 VanDerWaalsContact CZ-CG 3.5Å; F200-P259 HydrophobicContact CE1-CG 4.48Å; F200-P259 HydrophobicContact CZ-CB 4.47Å; F200-P259 HydrophobicContact CZ-CG 4.06Å; W257-P259 WeakPolarHBondContact O-CD 3.2Å; P259-T277 HydrophobicContact CB-CG2 4.3Å
260	E	91.3	Very high	89	Confident	27 Å²	27	46.5 Å²	46.5	13%	0.126	25%	0.248	C	C	.	.	P	Polyproline II helix	trans	-79.4	155.4	169.1	-170.1	56.3	-89.4	0	0	109.9	G148 R149 K150 F200 A262 Y264	G148-E260 WeakPolarHBondContact CA-OE2 3.1Å; R149-E260 PolarHBondContact N-OE1 3.15Å; R149-E260 PolarHBondContact N-OE2 3.22Å; K150-E260 VanDerWaalsContact CB-OE2 3.25Å; K150-E260 WeakPolarHBondContact CB-OE2 3.37Å; K150-E260 PolarHBondContact N-OE1 3.26Å; K150-E260 PolarHBondContact N-OE2 3.1Å; F200-E260 WeakPolarHBondContact CZ-O 3.42Å; E260-A262 PolarHBondContact O-N 2.67Å; E260-Y264 HydrophobicContact CG-CD1 3.69Å; E260-Y264 HydrophobicContact CG-CE1 4.26Å
261	S	89.2	Confident	88.6	Confident	2 Å²	2	46.4 Å²	46.4	1%	0.014	25%	0.245	C	C	.	.	P	Polyproline II helix	trans	-62.7	125.8	178.3	171.4	0	0	0	0	112.2	E199 R263 Y264 D265	E199-S261 WeakPolarHBondContact OE2-CB 3.49Å; E199-S261 PolarHBondContact OE2-OG 2.88Å; S261-R263 PolarHBondContact O-N 3.36Å; S261-R263 WeakPolarHBondContact OG-CB 3.21Å; S261-R263 PolarHBondContact OG-N 3.41Å; S261-R263 VanDerWaalsContact OG-N 3.13Å; S261-Y264 WeakPolarHBondContact O-CB 3.4Å; S261-Y264 PolarHBondContact O-N 3.33Å; S261-Y264 VanDerWaalsContact O-N 3.1Å; S261-Y264 PolarHBondContact OG-N 2.97Å; S261-D265 PolarHBondContact O-N 3.28Å
262	A	86.8	Confident	88.4	Confident	4 Å²	4	54.5 Å²	54.5	3%	0.033	28%	0.283	C	S	.	.	H	α-helix	trans	-58.2	-31.3	172.4	0	0	0	0	0	111.7	V70 E260 D265 V266 A274 T277 L278	V70-A262 HydrophobicContact CG1-CB 3.9Å; E260-A262 PolarHBondContact O-N 2.67Å; A262-D265 PolarHBondContact O-N 2.83Å; A262-V266 WeakPolarHBondContact O-CG2 3.31Å; A262-V266 PolarHBondContact O-N 3.49Å; A262-V266 VanDerWaalsContact O-N 3.08Å; A262-A274 HydrophobicContact CB-CB 4.41Å; A262-A274 WeakPolarHBondContact O-CB 3.37Å; A262-T277 HydrophobicContact CB-CG2 4.22Å; A262-L278 HydrophobicContact CB-CD2 4.19Å; A262-L278 HydrophobicContact CB-CG 4.12Å
263	R	85.6	Confident	88.2	Confident	93 Å²	93	59.7 Å²	59.7	35%	0.351	30%	0.303	S	S	.	.	H	α-helix	trans	-68	-44.1	176.4	-167.6	179.9	-170.6	-171.8	4.5	111.6	E71 S261 L267	E71-R263 IonicContact OE1-CZ 3.96Å; E71-R263 IonicContact OE1-NE 3.67Å; E71-R263 PolarHBondContact OE1-NE 3.3Å; E71-R263 IonicContact OE1-NH2 3.55Å; S261-R263 PolarHBondContact O-N 3.36Å; S261-R263 WeakPolarHBondContact OG-CB 3.21Å; S261-R263 PolarHBondContact OG-N 3.41Å; S261-R263 VanDerWaalsContact OG-N 3.13Å; R263-L267 HydrophobicContact CG-CD1 4.31Å; R263-L267 VanDerWaalsContact O-CG 3.31Å; R263-L267 WeakPolarHBondContact O-CG 3.31Å; R263-L267 PolarHBondContact O-N 2.99Å; R263-L267 VanDerWaalsContact O-N 3.12Å
264	Y	86.1	Confident	88	Confident	48 Å²	48	55.1 Å²	55.1	19%	0.188	28%	0.275	C	S	.	.	H	α-helix	trans	-62.4	-43.7	175.1	170.4	-96.5	0	0	0	111.5	D145 Q146 Y147 G148 E260 S261 V266 L267 S268	D145-Y264 WeakPolarHBondContact O-CE2 2.94Å; Q146-Y264 PolarHBondContact O-OH 2.79Å; Y147-Y264 VanDerWaalsContact C-OH 3.27Å; G148-Y264 VanDerWaalsContact CA-CZ 3.45Å; G148-Y264 VanDerWaalsContact N-CZ 3.26Å; G148-Y264 PolarHBondContact N-OH 3.19Å; E260-Y264 HydrophobicContact CG-CD1 3.69Å; E260-Y264 HydrophobicContact CG-CE1 4.26Å; S261-Y264 WeakPolarHBondContact O-CB 3.4Å; S261-Y264 PolarHBondContact O-N 3.33Å; S261-Y264 VanDerWaalsContact O-N 3.1Å; S261-Y264 PolarHBondContact OG-N 2.97Å; Y264-V266 PolarHBondContact O-N 3.2Å; Y264-L267 PolarHBondContact O-N 3.21Å; Y264-S268 WeakPolarHBondContact CE2-OG 3.27Å; Y264-S268 VanDerWaalsContact CZ-OG 3.27Å; Y264-S268 WeakPolarHBondContact O-CB 3.48Å; Y264-S268 PolarHBondContact O-N 3.14Å; Y264-S268 PolarHBondContact O-OG 3.33Å
265	D	88.3	Confident	87.9	Confident	9 Å²	9	54.4 Å²	54.4	5%	0.048	27%	0.271	C	S	.	.	H	α-helix	trans	-62.2	-42.8	179.8	-80.8	-29.7	0	0	0	112.1	S261 A262 S268 G269 N270 K273 A274	S261-D265 PolarHBondContact O-N 3.28Å; A262-D265 PolarHBondContact O-N 2.83Å; D265-S268 PolarHBondContact O-N 3.32Å; D265-G269 PolarHBondContact O-N 3.32Å; D265-N270 HydrophobicContact CB-CB 4.48Å; D265-N270 CarbonylContact O-C 3.57Å; D265-N270 WeakPolarHBondContact O-CA 3.23Å; D265-N270 PolarHBondContact O-N 3.07Å; D265-K273 HydrophobicContact CB-CB 4.27Å; D265-A274 HydrophobicContact CB-CB 3.84Å
266	V	87.3	Confident	87.9	Confident	6 Å²	6	57.1 Å²	57.1	4%	0.036	29%	0.294	C	S	.	.	H	α-helix	trans	-61.5	-45.8	174.7	169.2	0	0	0	0	111.7	V70 A262 Y264 S268 G269 A274 L294 I296	V70-V266 HydrophobicContact CG2-CB 4.35Å; V70-V266 HydrophobicContact CG2-CG2 3.68Å; A262-V266 WeakPolarHBondContact O-CG2 3.31Å; A262-V266 PolarHBondContact O-N 3.49Å; A262-V266 VanDerWaalsContact O-N 3.08Å; Y264-V266 PolarHBondContact O-N 3.2Å; V266-S268 VanDerWaalsContact C-N 3.3Å; V266-S268 PolarHBondContact O-N 2.83Å; V266-G269 PolarHBondContact O-N 2.97Å; V266-A274 HydrophobicContact CG2-CB 3.4Å; V266-L294 HydrophobicContact CG2-CD1 4.43Å; V266-L294 HydrophobicContact CG2-CD2 3.41Å; V266-L294 VanDerWaalsContact CG2-CD2 3.41Å; V266-L294 HydrophobicContact CG2-CG 3.96Å; V266-I296 HydrophobicContact CG1-CB 4.17Å; V266-I296 HydrophobicContact CG1-CG1 3.5Å; V266-I296 VanDerWaalsContact CG1-CG1 3.5Å; V266-I296 HydrophobicContact CG1-CG2 4.41Å
267	L	83.5	Confident	88.1	Confident	84 Å²	84	51 Å²	51	44%	0.44	27%	0.268	S	S	.	.	H	α-helix	trans	-68.4	-30.1	-180	-70.7	172.3	0	0	0	112.9	R263 Y264 G269 I296	R263-L267 HydrophobicContact CG-CD1 4.31Å; R263-L267 VanDerWaalsContact O-CG 3.31Å; R263-L267 WeakPolarHBondContact O-CG 3.31Å; R263-L267 PolarHBondContact O-N 2.99Å; R263-L267 VanDerWaalsContact O-N 3.12Å; Y264-L267 PolarHBondContact O-N 3.21Å; L267-G269 PolarHBondContact O-N 3.29Å; L267-I296 HydrophobicContact CD2-CG2 3.93Å
268	S	84.6	Confident	88.1	Confident	54 Å²	54	47.2 Å²	47.2	38%	0.378	25%	0.254	S	S	.	.	T	Hydrogen-bonded Turn	trans	-78.5	-0.1	176	-56.4	0	0	0	0	113.1	Y264 D265 V266 N270	Y264-S268 WeakPolarHBondContact CE2-OG 3.27Å; Y264-S268 VanDerWaalsContact CZ-OG 3.27Å; Y264-S268 WeakPolarHBondContact O-CB 3.48Å; Y264-S268 PolarHBondContact O-N 3.14Å; Y264-S268 PolarHBondContact O-OG 3.33Å; D265-S268 PolarHBondContact O-N 3.32Å; V266-S268 VanDerWaalsContact C-N 3.3Å; V266-S268 PolarHBondContact O-N 2.83Å; S268-N270 VanDerWaalsContact C-N 3.33Å
269	G	83.8	Confident	88.1	Confident	57 Å²	57	51.8 Å²	51.8	59%	0.588	27%	0.274	S	S	*	.	T	Hydrogen-bonded Turn	trans	83.1	2.3	-177.5	0	0	0	0	0	114.7	D265 V266 L267 Q271	D265-G269 PolarHBondContact O-N 3.32Å; V266-G269 PolarHBondContact O-N 2.97Å; L267-G269 PolarHBondContact O-N 3.29Å; G269-Q271 PolarHBondContact O-N 2.95Å
270	N	87.4	Confident	88.1	Confident	69 Å²	69	55.3 Å²	55.3	37%	0.369	29%	0.286	S	S	.	.			trans	-91.3	62.4	-178.4	-65.6	-38.6	0	0	0	111.6	D265 S268 E272 K273 A274	D265-N270 HydrophobicContact CB-CB 4.48Å; D265-N270 CarbonylContact O-C 3.57Å; D265-N270 WeakPolarHBondContact O-CA 3.23Å; D265-N270 PolarHBondContact O-N 3.07Å; S268-N270 VanDerWaalsContact C-N 3.33Å; N270-E272 VanDerWaalsContact C-N 3.27Å; N270-E272 PolarHBondContact O-N 3.32Å; N270-K273 HydrophobicContact CB-CB 4.28Å; N270-K273 HydrophobicContact CB-CD 4.17Å; N270-K273 HydrophobicContact CB-CG 4.39Å; N270-K273 PolarHBondContact O-N 3.47Å; N270-A274 PolarHBondContact O-N 3.14Å
271	Q	86	Confident	88.1	Confident	85 Å²	85	54.1 Å²	54.1	40%	0.397	28%	0.281	S	S	.	.	H	α-helix	trans	-58.9	-35	-175.9	-66.4	-168.2	-44.1	0	0	113.7	G269 K273 A274 I275 L294	G269-Q271 PolarHBondContact O-N 2.95Å; Q271-K273 PolarHBondContact O-N 3.17Å; Q271-A274 PolarHBondContact O-N 3.18Å; Q271-I275 WeakPolarHBondContact O-CG1 3.46Å; Q271-I275 PolarHBondContact O-N 3.43Å; Q271-L294 PolarHBondContact NE2-O 3.41Å
272	E	88.3	Confident	88.2	Confident	172 Å²	172	54.1 Å²	54.1	80%	0.804	28%	0.281	S	S	*	.	H	α-helix	trans	-62.7	-41.8	178.5	-65.6	-177	175.4	0	0	112.4	N270 I275 A276	N270-E272 VanDerWaalsContact C-N 3.27Å; N270-E272 PolarHBondContact O-N 3.32Å; E272-I275 PolarHBondContact O-N 3.09Å; E272-A276 WeakPolarHBondContact O-CB 3.38Å; E272-A276 PolarHBondContact O-N 3.41Å
273	K	89.1	Confident	88.4	Confident	122 Å²	122	57.5 Å²	57.5	53%	0.53	30%	0.301	S	S	.	.	H	α-helix	trans	-66	-40.5	176.9	-70.8	-176	-179.3	171.7	0	111.4	D265 N270 Q271 I275 A276 T277	D265-K273 HydrophobicContact CB-CB 4.27Å; N270-K273 HydrophobicContact CB-CB 4.28Å; N270-K273 HydrophobicContact CB-CD 4.17Å; N270-K273 HydrophobicContact CB-CG 4.39Å; N270-K273 PolarHBondContact O-N 3.47Å; Q271-K273 PolarHBondContact O-N 3.17Å; K273-I275 PolarHBondContact O-N 3.4Å; K273-A276 PolarHBondContact O-N 2.96Å; K273-T277 PolarHBondContact O-N 3.17Å; K273-T277 PolarHBondContact O-OG1 3.42Å; K273-T277 VanDerWaalsContact O-OG1 3.11Å
274	A	88.9	Confident	88.7	Confident	0 Å²	0	55.2 Å²	55.2	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-61	-45.1	176.2	0	0	0	0	0	112	A262 D265 V266 N270 Q271 T277 L278 L294	A262-A274 HydrophobicContact CB-CB 4.41Å; A262-A274 WeakPolarHBondContact O-CB 3.37Å; D265-A274 HydrophobicContact CB-CB 3.84Å; V266-A274 HydrophobicContact CG2-CB 3.4Å; N270-A274 PolarHBondContact O-N 3.14Å; Q271-A274 PolarHBondContact O-N 3.18Å; A274-T277 PolarHBondContact O-N 2.98Å; A274-L278 WeakPolarHBondContact O-CG 3.29Å; A274-L278 PolarHBondContact O-N 3Å; A274-L294 HydrophobicContact CB-CD2 3.86Å
275	I	90.1	Very high	88.9	Confident	73 Å²	73	54.5 Å²	54.5	37%	0.374	29%	0.294	S	S	.	.	H	α-helix	trans	-64.1	-42	176.5	-66.3	168.6	0	0	0	110.7	Q271 E272 K273 T277 L278 K279 L294	Q271-I275 WeakPolarHBondContact O-CG1 3.46Å; Q271-I275 PolarHBondContact O-N 3.43Å; E272-I275 PolarHBondContact O-N 3.09Å; K273-I275 PolarHBondContact O-N 3.4Å; I275-T277 VanDerWaalsContact C-N 3.33Å; I275-T277 PolarHBondContact O-N 3.29Å; I275-L278 PolarHBondContact O-N 3.43Å; I275-K279 VanDerWaalsContact O-CB 3.3Å; I275-K279 WeakPolarHBondContact O-CB 3.37Å; I275-K279 PolarHBondContact O-N 3.47Å; I275-L294 HydrophobicContact CD1-CB 4.46Å; I275-L294 HydrophobicContact CG1-CB 4.41Å; I275-L294 HydrophobicContact CG1-CD2 3.85Å
276	A	91.1	Very high	88.9	Confident	59 Å²	59	56.4 Å²	56.4	49%	0.488	32%	0.315	S	S	.	.	H	α-helix	trans	-60.9	-42.2	176.1	0	0	0	0	0	112	E272 K273 K279 R280	E272-A276 WeakPolarHBondContact O-CB 3.38Å; E272-A276 PolarHBondContact O-N 3.41Å; K273-A276 PolarHBondContact O-N 2.96Å; A276-K279 PolarHBondContact O-N 3.25Å; A276-R280 PolarHBondContact O-N 3.36Å
277	T	91.7	Very high	88.8	Confident	19 Å²	19	56.7 Å²	56.7	12%	0.117	32%	0.319	C	S	.	.	H	α-helix	trans	-62.5	-48.8	174.4	-63.5	0	0	0	0	111.1	F200 P259 A262 K273 A274 I275 K279 R280 I281	F200-T277 HydrophobicContact CE1-CG2 3.94Å; F200-T277 HydrophobicContact CZ-CG2 4.47Å; P259-T277 HydrophobicContact CB-CG2 4.3Å; A262-T277 HydrophobicContact CB-CG2 4.22Å; K273-T277 PolarHBondContact O-N 3.17Å; K273-T277 PolarHBondContact O-OG1 3.42Å; K273-T277 VanDerWaalsContact O-OG1 3.11Å; A274-T277 PolarHBondContact O-N 2.98Å; I275-T277 VanDerWaalsContact C-N 3.33Å; I275-T277 PolarHBondContact O-N 3.29Å; T277-K279 VanDerWaalsContact C-N 3.33Å; T277-K279 PolarHBondContact O-N 3.21Å; T277-R280 WeakPolarHBondContact O-CB 3.48Å; T277-R280 PolarHBondContact O-N 2.67Å; T277-R280 VanDerWaalsContact O-N 3.13Å; T277-I281 HydrophobicContact CG2-CD1 4.37Å; T277-I281 WeakPolarHBondContact O-CG1 3.49Å; T277-I281 PolarHBondContact O-N 3.45Å
278	L	90.6	Very high	88.7	Confident	0 Å²	0	53.7 Å²	53.7	0%	0	30%	0.304	C	S	.	.	H	α-helix	trans	-61	-40.5	177.3	-69.4	171.7	0	0	0	112.3	F68 V70 A73 V74 I77 A262 A274 I275 R280 I281 A282 M289	F68-L278 HydrophobicContact CE2-CD1 4.38Å; V70-L278 HydrophobicContact CG1-CD2 4.46Å; A73-L278 HydrophobicContact CB-CD1 3.92Å; A73-L278 HydrophobicContact CB-CD2 4.05Å; V74-L278 HydrophobicContact CG2-CD2 4.11Å; I77-L278 HydrophobicContact CD1-CD2 4.5Å; A262-L278 HydrophobicContact CB-CD2 4.19Å; A262-L278 HydrophobicContact CB-CG 4.12Å; A274-L278 WeakPolarHBondContact O-CG 3.29Å; A274-L278 PolarHBondContact O-N 3Å; I275-L278 PolarHBondContact O-N 3.43Å; L278-R280 VanDerWaalsContact C-N 3.32Å; L278-R280 PolarHBondContact O-N 3.38Å; L278-I281 HydrophobicContact CD2-CD1 4.28Å; L278-I281 PolarHBondContact O-N 3.38Å; L278-I281 VanDerWaalsContact O-N 3.17Å; L278-A282 WeakPolarHBondContact O-CB 3.49Å; L278-A282 PolarHBondContact O-N 3.42Å; L278-M289 HydrophobicContact CB-CE 3.61Å; L278-M289 HydrophobicContact CB-SD 3.9Å; L278-M289 HydrophobicContact CD1-CE 3.89Å; L278-M289 HydrophobicContact CG-CE 4.39Å
279	K	90.4	Very high	88.6	Confident	97 Å²	97	53.2 Å²	53.2	42%	0.422	30%	0.296	S	S	.	.	H	α-helix	trans	-62.2	-38.5	174.8	-172.5	178.5	-178.8	-178.6	0	111.8	I275 A276 T277 A282 T283	I275-K279 VanDerWaalsContact O-CB 3.3Å; I275-K279 WeakPolarHBondContact O-CB 3.37Å; I275-K279 PolarHBondContact O-N 3.47Å; A276-K279 PolarHBondContact O-N 3.25Å; T277-K279 VanDerWaalsContact C-N 3.33Å; T277-K279 PolarHBondContact O-N 3.21Å; K279-A282 PolarHBondContact O-N 3.33Å; K279-T283 WeakPolarHBondContact O-CB 3.5Å; K279-T283 VanDerWaalsContact O-CG2 3.31Å; K279-T283 WeakPolarHBondContact O-CG2 3.37Å; K279-T283 PolarHBondContact O-N 3.44Å; K279-T283 PolarHBondContact O-OG1 2.96Å
280	R	91.3	Very high	88.3	Confident	81 Å²	81	51.1 Å²	51.1	31%	0.306	27%	0.273	S	S	.	.	H	α-helix	trans	-63.2	-42.2	173.4	-179.1	177	170.9	-168.5	-5.7	111.8	W257 A276 T277 L278 T283 E284	W257-R280 VanDerWaalsContact CD1-NH2 3.26Å; W257-R280 PolarHBondContact O-NH1 3.03Å; W257-R280 PolarHBondContact O-NH2 3.25Å; A276-R280 PolarHBondContact O-N 3.36Å; T277-R280 WeakPolarHBondContact O-CB 3.48Å; T277-R280 PolarHBondContact O-N 2.67Å; T277-R280 VanDerWaalsContact O-N 3.13Å; L278-R280 VanDerWaalsContact C-N 3.32Å; L278-R280 PolarHBondContact O-N 3.38Å; R280-T283 WeakPolarHBondContact CA-OG1 3.29Å; R280-T283 PolarHBondContact O-OG1 3.14Å; R280-E284 IonicContact NE-OE1 3.14Å; R280-E284 PolarHBondContact NE-OE1 3.38Å; R280-E284 IonicContact NH2-OE1 4Å; R280-E284 WeakPolarHBondContact O-CB 3.34Å; R280-E284 WeakPolarHBondContact O-CG 3.39Å; R280-E284 PolarHBondContact O-N 2.99Å
281	I	91.3	Very high	87.5	Confident	2 Å²	2	52.7 Å²	52.7	1%	0.01	28%	0.281	C	S	.	.	H	α-helix	trans	-64.2	-47.2	176.8	-55.9	165.8	0	0	0	110	I77 F82 F200 T277 L278 T283 E284 N285	I77-I281 HydrophobicContact CD1-CB 4.49Å; I77-I281 HydrophobicContact CG2-CB 4.48Å; I77-I281 HydrophobicContact CG2-CG2 3.69Å; F82-I281 HydrophobicContact CB-CG2 4.38Å; F82-I281 HydrophobicContact CD1-CB 4.36Å; F82-I281 HydrophobicContact CD1-CG1 3.91Å; F82-I281 HydrophobicContact CD1-CG2 3.84Å; F82-I281 HydrophobicContact CD2-CG1 4.35Å; F82-I281 HydrophobicContact CE1-CD1 4.14Å; F82-I281 HydrophobicContact CE1-CG1 3.67Å; F82-I281 HydrophobicContact CE1-CG2 4.37Å; F82-I281 HydrophobicContact CE2-CG1 4.12Å; F82-I281 HydrophobicContact CG-CB 4.46Å; F82-I281 HydrophobicContact CG-CG1 4.23Å; F82-I281 HydrophobicContact CG-CG2 4.14Å; F82-I281 HydrophobicContact CZ-CD1 4.41Å; F82-I281 HydrophobicContact CZ-CG1 3.76Å; F200-I281 HydrophobicContact CD1-CD1 3.59Å; F200-I281 HydrophobicContact CE1-CD1 3.84Å; T277-I281 HydrophobicContact CG2-CD1 4.37Å; T277-I281 WeakPolarHBondContact O-CG1 3.49Å; T277-I281 PolarHBondContact O-N 3.45Å; L278-I281 HydrophobicContact CD2-CD1 4.28Å; L278-I281 PolarHBondContact O-N 3.38Å; L278-I281 VanDerWaalsContact O-N 3.17Å; I281-T283 PolarHBondContact O-N 3.38Å; I281-E284 PolarHBondContact O-N 2.87Å; I281-N285 VanDerWaalsContact O-CB 3.3Å; I281-N285 WeakPolarHBondContact O-CB 3.02Å; I281-N285 PolarHBondContact O-N 3.17Å
282	A	89.7	Confident	87	Confident	2 Å²	2	50.4 Å²	50.4	2%	0.017	28%	0.28	C	S	.	.	H	α-helix	trans	-58.4	-47	179.3	0	0	0	0	0	111.9	I77 L278 K279 N285 G286 A287	I77-A282 HydrophobicContact CD1-CB 3.98Å; I77-A282 HydrophobicContact CG1-CB 4.07Å; L278-A282 WeakPolarHBondContact O-CB 3.49Å; L278-A282 PolarHBondContact O-N 3.42Å; K279-A282 PolarHBondContact O-N 3.33Å; A282-N285 PolarHBondContact O-N 2.95Å; A282-G286 PolarHBondContact O-N 2.94Å; A282-A287 CarbonylContact C-O 3.59Å; A282-A287 WeakPolarHBondContact CB-O 3.2Å; A282-A287 PolarHBondContact O-N 3.38Å
283	T	90.9	Very high	86.6	Confident	76 Å²	76	48.7 Å²	48.7	47%	0.466	27%	0.269	S	S	.	.	H	α-helix	trans	-65.2	-44.9	178.1	48.2	0	0	0	0	112.9	L11 K279 R280 I281 N285 G286	L11-T283 HydrophobicContact CD1-CG2 4.2Å; K279-T283 WeakPolarHBondContact O-CB 3.5Å; K279-T283 VanDerWaalsContact O-CG2 3.31Å; K279-T283 WeakPolarHBondContact O-CG2 3.37Å; K279-T283 PolarHBondContact O-N 3.44Å; K279-T283 PolarHBondContact O-OG1 2.96Å; R280-T283 WeakPolarHBondContact CA-OG1 3.29Å; R280-T283 PolarHBondContact O-OG1 3.14Å; I281-T283 PolarHBondContact O-N 3.38Å; T283-N285 VanDerWaalsContact C-N 3.29Å; T283-N285 PolarHBondContact O-N 2.87Å; T283-G286 PolarHBondContact O-N 3.48Å
284	E	91.8	Very high	86.3	Confident	44 Å²	44	43.4 Å²	43.4	21%	0.206	25%	0.247	C	C	.	.	H	α-helix	trans	-67.1	-30.2	177.8	-75.2	-163.3	-137.5	0	0	112.9	F82 K85 R280 I281	F82-E284 HydrophobicContact CB-CB 3.99Å; K85-E284 IonicContact NZ-OE2 3.77Å; K85-E284 PolarHBondContact NZ-OE2 3.22Å; R280-E284 IonicContact NE-OE1 3.14Å; R280-E284 PolarHBondContact NE-OE1 3.38Å; R280-E284 IonicContact NH2-OE1 4Å; R280-E284 WeakPolarHBondContact O-CB 3.34Å; R280-E284 WeakPolarHBondContact O-CG 3.39Å; R280-E284 PolarHBondContact O-N 2.99Å; I281-E284 PolarHBondContact O-N 2.87Å
285	N	91.6	Very high	85.9	Confident	34 Å²	34	46.3 Å²	46.3	18%	0.182	26%	0.262	C	S	.	.	H	α-helix	trans	-86.3	-10.7	176.4	-72.6	-6.9	0	0	0	113.6	I77 G78 G80 K81 F82 Q83 I281 A282 T283 A287	I77-N285 HydrophobicContact CG2-CB 4.19Å; G78-N285 PolarHBondContact O-ND2 3.4Å; G80-N285 VanDerWaalsContact C-OD1 3.27Å; G80-N285 VanDerWaalsContact CA-OD1 3.3Å; G80-N285 WeakPolarHBondContact CA-OD1 3.4Å; K81-N285 PolarHBondContact N-OD1 3.07Å; F82-N285 WeakPolarHBondContact CB-OD1 3.42Å; F82-N285 PolarHBondContact N-OD1 3.17Å; Q83-N285 PolarHBondContact NE2-ND2 3.16Å; Q83-N285 PolarHBondContact OE1-ND2 3.43Å; Q83-N285 PolarHBondContact OE1-OD1 3.41Å; I281-N285 VanDerWaalsContact O-CB 3.3Å; I281-N285 WeakPolarHBondContact O-CB 3.02Å; I281-N285 PolarHBondContact O-N 3.17Å; A282-N285 PolarHBondContact O-N 2.95Å; T283-N285 VanDerWaalsContact C-N 3.29Å; T283-N285 PolarHBondContact O-N 2.87Å; N285-A287 HydrophobicContact CB-CB 4.37Å; N285-A287 PolarHBondContact O-N 3.37Å
286	G	87.6	Confident	85.4	Confident	48 Å²	48	47.2 Å²	47.2	50%	0.495	27%	0.267	S	S	.	.	T	Hydrogen-bonded Turn	trans	65.9	24.8	-173.5	0	0	0	0	0	113.2	A282 T283	A282-G286 PolarHBondContact O-N 2.94Å; T283-G286 PolarHBondContact O-N 3.48Å
287	A	86	Confident	84.2	Confident	13 Å²	13	46.1 Å²	46.1	11%	0.107	26%	0.255	C	S	.	.	P	Polyproline II helix	trans	-103.7	151.5	-178.7	0	0	0	0	0	110.7	I77 A282 N285	I77-A287 HydrophobicContact CB-CB 4.48Å; I77-A287 HydrophobicContact CG2-CB 4.12Å; I77-A287 WeakPolarHBondContact O-CB 3.26Å; A282-A287 CarbonylContact C-O 3.59Å; A282-A287 WeakPolarHBondContact CB-O 3.2Å; A282-A287 PolarHBondContact O-N 3.38Å; N285-A287 HydrophobicContact CB-CB 4.37Å; N285-A287 PolarHBondContact O-N 3.37Å
288	P	81.6	Confident	82.6	Confident	20 Å²	20	56.6 Å²	56.6	13%	0.13	29%	0.293	C	S	.	.	P	Polyproline II helix	trans	-69.8	151.1	173.3	28.8	-36.4	0	0	0	113.7	P12 V14	P12-P288 WeakPolarHBondContact O-CB 3.36Å; P12-P288 WeakPolarHBondContact O-CG 3.24Å; V14-P288 HydrophobicContact CB-CG 4.39Å; V14-P288 HydrophobicContact CG2-CG 3.92Å
289	M	82.1	Confident	81	Confident	44 Å²	44	61 Å²	61	22%	0.217	31%	0.313	C	S	.	.	P	Polyproline II helix	trans	-80.2	137.1	167.2	-169.8	72.7	-168	0	0	109.9	F68 I77 L278	F68-M289 HydrophobicContact CE2-CE 3.86Å; F68-M289 HydrophobicContact CZ-CE 3.67Å; I77-M289 HydrophobicContact CD1-SD 4.48Å; L278-M289 HydrophobicContact CB-CE 3.61Å; L278-M289 HydrophobicContact CB-SD 3.9Å; L278-M289 HydrophobicContact CD1-CE 3.89Å; L278-M289 HydrophobicContact CG-CE 4.39Å
290	P	76.9	Confident	79.5	Confident	14 Å²	14	61 Å²	61	9%	0.091	32%	0.315	C	S	.	.	P	Polyproline II helix	trans	-62.2	144.9	170.1	27.6	-36.5	0	0	0	111.3	F68 A73	F68-P290 HydrophobicContact CD1-CB 4.25Å; F68-P290 HydrophobicContact CD1-CG 4.27Å; F68-P290 HydrophobicContact CD2-CG 3.92Å; F68-P290 HydrophobicContact CE1-CG 4.29Å; F68-P290 HydrophobicContact CE2-CG 3.96Å; F68-P290 HydrophobicContact CG-CB 4.26Å; F68-P290 HydrophobicContact CG-CG 4.09Å; F68-P290 HydrophobicContact CZ-CG 4.16Å; A73-P290 HydrophobicContact CB-CG 3.77Å
291	L	70.1	Confident	78	Confident	102 Å²	102	64.5 Å²	64.5	53%	0.534	34%	0.34	S	S	.	.	P	Polyproline II helix	trans	-83.9	138.1	175.3	-64.4	172.4	0	0	0	110.1	V13	V13-L291 HydrophobicContact CG1-CD1 3.81Å; V13-L291 HydrophobicContact CG1-CD2 4.14Å; V13-L291 HydrophobicContact CG1-CG 3.76Å
292	G	76.9	Confident	76.9	Confident	37 Å²	37	72 Å²	72	38%	0.381	37%	0.368	S	S	.	.	S	Bend	trans	139.7	-176.3	172.5	0	0	0	0	0	115.2	D66 F68	D66-G292 CarbonylContact O-C 3.45Å; D66-G292 VanDerWaalsContact O-C 3.31Å; D66-G292 WeakPolarHBondContact O-CA 3.24Å; F68-G292 VanDerWaalsContact CE1-O 3.23Å; F68-G292 WeakPolarHBondContact CE1-O 3.41Å
293	K	78.8	Confident	76	Confident	135 Å²	135	72.7 Å²	72.7	59%	0.587	37%	0.374	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-90.8	130.1	172.1	-70.4	178	-177.2	168	0	110.3	D66 T67 F68 I295	D66-K293 PolarHBondContact O-N 3.13Å; T67-K293 VanDerWaalsContact CA-O 3.28Å; T67-K293 WeakPolarHBondContact CA-O 3.42Å; T67-K293 HydrophobicContact CG2-CB 4.44Å; F68-K293 PolarHBondContact N-O 2.97Å; F68-K293 VanDerWaalsContact N-O 3.12Å; K293-I295 PolarHBondContact O-N 3.48Å
294	L	82.1	Confident	75.6	Confident	11 Å²	11	76.5 Å²	76.5	6%	0.058	39%	0.385	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-69.1	116.1	175.5	-177.6	58.5	0	0	0	109.6	F68 V70 V266 Q271 A274 I275	F68-L294 HydrophobicContact CD2-CD1 4.08Å; F68-L294 HydrophobicContact CE2-CB 4.4Å; F68-L294 HydrophobicContact CE2-CD1 3.82Å; F68-L294 HydrophobicContact CZ-CB 4.42Å; F68-L294 WeakPolarHBondContact O-CA 3.33Å; V70-L294 HydrophobicContact CG2-CD1 3.91Å; V266-L294 HydrophobicContact CG2-CD1 4.43Å; V266-L294 HydrophobicContact CG2-CD2 3.41Å; V266-L294 VanDerWaalsContact CG2-CD2 3.41Å; V266-L294 HydrophobicContact CG2-CG 3.96Å; Q271-L294 PolarHBondContact NE2-O 3.41Å; A274-L294 HydrophobicContact CB-CD2 3.86Å; I275-L294 HydrophobicContact CD1-CB 4.46Å; I275-L294 HydrophobicContact CG1-CB 4.41Å; I275-L294 HydrophobicContact CG1-CD2 3.85Å
295	I	82.4	Confident	75.2	Confident	61 Å²	61	79 Å²	79	31%	0.313	40%	0.398	S	S	.	.			trans	-105.5	150	176.9	55.5	165.7	0	0	0	110.8	T67 F68 M69 K293	T67-I295 HydrophobicContact CG2-CG2 3.77Å; F68-I295 PolarHBondContact O-N 3.17Å; F68-I295 VanDerWaalsContact O-N 3.07Å; M69-I295 HydrophobicContact CE-CD1 3.86Å; M69-I295 HydrophobicContact CE-CG1 4.5Å; M69-I295 HydrophobicContact CG-CD1 4.25Å; M69-I295 HydrophobicContact CG-CG1 4.05Å; K293-I295 PolarHBondContact O-N 3.48Å
296	I	77.9	Confident	74.9	Confident	93 Å²	93	87.4 Å²	87.4	48%	0.477	43%	0.427	S	S	.	.			trans	-76.3	126.6	175.7	-58.3	160	0	0	0	107.8	V266 L267 R298	V266-I296 HydrophobicContact CG1-CB 4.17Å; V266-I296 HydrophobicContact CG1-CG1 3.5Å; V266-I296 VanDerWaalsContact CG1-CG1 3.5Å; V266-I296 HydrophobicContact CG1-CG2 4.41Å; L267-I296 HydrophobicContact CD2-CG2 3.93Å; I296-R298 PolarHBondContact O-N 2.66Å
297	S	66.3	Low	74.7	Confident	35 Å²	35	87.3 Å²	87.3	25%	0.245	42%	0.415	C	S	.	.			trans	-53.4	124.2	166.8	151.4	0	0	0	0	109.1	Q299	S297-Q299 VanDerWaalsContact C-N 3.33Å; S297-Q299 PolarHBondContact O-N 2.89Å
298	R	57.5	Low	74.6	Confident	240 Å²	240	86.7 Å²	86.7	91%	0.906	41%	0.41	S	S	*	.			trans	-66.9	97.7	172.7	-160.9	175.5	-176.1	167.7	0.7	106.7	I296 E300	I296-R298 PolarHBondContact O-N 2.66Å; R298-E300 PolarHBondContact O-N 3.35Å; R298-E300 VanDerWaalsContact O-N 3.12Å
299	Q	58.6	Low	74.9	Confident	92 Å²	92	89.9 Å²	89.9	43%	0.43	42%	0.422	S	S	.	.	P	Polyproline II helix	trans	-59.8	118.2	-178.2	-146.4	172	30	0	0	107.5	S297 D301	S297-Q299 VanDerWaalsContact C-N 3.33Å; S297-Q299 PolarHBondContact O-N 2.89Å; Q299-D301 PolarHBondContact O-N 3.42Å
300	E	57.7	Low	75.1	Confident	97 Å²	97	89.6 Å²	89.6	45%	0.453	42%	0.423	S	S	.	.	P	Polyproline II helix	trans	-55.1	137.1	164.6	-69.7	-171.7	144.4	0	0	107.6	R298 R302	R298-E300 PolarHBondContact O-N 3.35Å; R298-E300 VanDerWaalsContact O-N 3.12Å; E300-R302 PolarHBondContact O-N 3.03Å
301	D	61	Low	75.3	Confident	155 Å²	155	93.3 Å²	93.3	83%	0.829	45%	0.446	S	S	*	.	P	Polyproline II helix	trans	-49.7	120	178.8	-78.2	-41	0	0	0	109.2	Q299 G303	Q299-D301 PolarHBondContact O-N 3.42Å; D301-G303 PolarHBondContact O-N 3.13Å
302	R	67.4	Low	75.8	Confident	160 Å²	160	91.9 Å²	91.9	60%	0.604	44%	0.437	S	S	*	.	P	Polyproline II helix	trans	-53.9	127.7	177.6	-72.1	-172.4	-179.4	-173.1	0.7	107.9	D145 E300	D145-R302 IonicContact OD2-CZ 2.76Å; D145-R302 IonicContact OD2-NH1 3.24Å; D145-R302 PolarHBondContact OD2-NH1 2.96Å; D145-R302 IonicContact OD2-NH2 2.84Å; E300-R302 PolarHBondContact O-N 3.03Å
303	G	69.9	Low	76.2	Confident	15 Å²	15	90.3 Å²	90.3	16%	0.155	42%	0.42	C	S	.	.	P	Polyproline II helix	trans	-58.4	144.2	177.5	0	0	0	0	0	111.3	D301 D307 A455 L459	D301-G303 PolarHBondContact O-N 3.13Å; G303-D307 WeakPolarHBondContact CA-OD2 3.25Å; G303-A455 PolarHBondContact N-O 3.18Å; G303-L459 WeakPolarHBondContact O-CD2 3.45Å
304	K	84.4	Confident	76.7	Confident	157 Å²	157	89.3 Å²	89.3	68%	0.683	41%	0.412	S	S	*	.	P	Polyproline II helix	trans	-84	156.2	176.1	-66	176.8	-177.3	174.1	0	109.4	R306 D307 L459	K304-R306 PolarHBondContact O-N 3.47Å; K304-R306 VanDerWaalsContact O-N 3.08Å; K304-D307 PolarHBondContact N-OD2 3.18Å; K304-D307 VanDerWaalsContact O-CB 3.26Å; K304-D307 WeakPolarHBondContact O-CB 3.2Å; K304-D307 PolarHBondContact O-N 2.77Å; K304-L459 WeakPolarHBondContact O-CD2 3.48Å
305	M	82.3	Confident	77	Confident	97 Å²	97	96.1 Å²	96.1	48%	0.478	44%	0.437	S	S	.	.	G	3₁₀ helix	trans	-59.7	-25.9	177.5	-170.1	151.7	-177	0	0	113.2	D307 L308 F309 W321 L459 T463	M305-D307 PolarHBondContact O-N 3.15Å; M305-L308 HydrophobicContact CG-CD1 4.48Å; M305-L308 PolarHBondContact O-N 3.14Å; M305-F309 HydrophobicContact CG-CE2 4.46Å; M305-F309 WeakPolarHBondContact O-CD2 3.25Å; M305-W321 HydrophobicContact CE-CH2 4.19Å; M305-W321 HydrophobicContact CE-CZ2 4.08Å; M305-L459 HydrophobicContact CB-CD2 4.39Å; M305-T463 HydrophobicContact CE-CG2 3.62Å; M305-T463 HydrophobicContact SD-CG2 4.21Å
306	R	85.1	Confident	77.5	Confident	210 Å²	210	93.2 Å²	93.2	79%	0.792	42%	0.423	S	S	*	.	G	3₁₀ helix	trans	-62.3	-29.3	172.2	-176.3	176.1	167.5	179	-4.1	112.8	K304 L308 F309	K304-R306 PolarHBondContact O-N 3.47Å; K304-R306 VanDerWaalsContact O-N 3.08Å; R306-L308 VanDerWaalsContact C-N 3.26Å; R306-L308 PolarHBondContact O-N 3.03Å; R306-F309 PolarHBondContact O-N 2.85Å; R306-F309 VanDerWaalsContact O-N 3.08Å
307	D	83.6	Confident	78.2	Confident	46 Å²	46	88.8 Å²	88.8	25%	0.246	40%	0.4	C	S	.	.	G	3₁₀ helix	trans	-70.7	-25.9	-175.2	-56.7	-21.4	0	0	0	111.5	G303 K304 M305 F309 T310 T456	G303-D307 WeakPolarHBondContact CA-OD2 3.25Å; K304-D307 PolarHBondContact N-OD2 3.18Å; K304-D307 VanDerWaalsContact O-CB 3.26Å; K304-D307 WeakPolarHBondContact O-CB 3.2Å; K304-D307 PolarHBondContact O-N 2.77Å; M305-D307 PolarHBondContact O-N 3.15Å; D307-F309 PolarHBondContact O-N 3Å; D307-T310 WeakPolarHBondContact O-CB 3.48Å; D307-T310 PolarHBondContact O-N 3.41Å; D307-T310 PolarHBondContact O-OG1 3.35Å; D307-T456 HydrophobicContact CB-CG2 4.08Å
308	L	84.6	Confident	79.5	Confident	0 Å²	0	91.2 Å²	91.2	0%	0	41%	0.409	C	S	.	.	G	3₁₀ helix	trans	-66.5	-24.3	171.9	-70.1	168.7	0	0	0	113.5	M305 R306 F313 T317 Y452 L459 T463	M305-L308 HydrophobicContact CG-CD1 4.48Å; M305-L308 PolarHBondContact O-N 3.14Å; R306-L308 VanDerWaalsContact C-N 3.26Å; R306-L308 PolarHBondContact O-N 3.03Å; L308-F313 CarbonylContact O-C 3.48Å; L308-F313 WeakPolarHBondContact O-CB 3.46Å; L308-T317 HydrophobicContact CB-CG2 4.24Å; L308-T317 PolarHBondContact O-OG1 2.81Å; L308-Y452 HydrophobicContact CD2-CD1 3.99Å; L308-Y452 HydrophobicContact CD2-CE1 3.45Å; L308-Y452 VanDerWaalsContact CD2-CE1 3.45Å; L308-L459 HydrophobicContact CD1-CD2 3.84Å; L308-L459 HydrophobicContact CD1-CG 3.77Å; L308-L459 HydrophobicContact CG-CD2 4.16Å; L308-L459 HydrophobicContact CG-CG 4.47Å; L308-T463 HydrophobicContact CD1-CG2 3.87Å
309	F	88.2	Confident	81.3	Confident	87 Å²	87	81.2 Å²	81.2	38%	0.382	37%	0.374	S	S	.	.	G	3₁₀ helix	trans	-101.3	11.2	-178.8	-65.1	-78.6	0	0	0	113.1	M305 R306 D307 W321	M305-F309 HydrophobicContact CG-CE2 4.46Å; M305-F309 WeakPolarHBondContact O-CD2 3.25Å; R306-F309 PolarHBondContact O-N 2.85Å; R306-F309 VanDerWaalsContact O-N 3.08Å; D307-F309 PolarHBondContact O-N 3Å; F309-W321 HydrophobicContact CE1-CH2 4.46Å; F309-W321 HydrophobicContact CE2-CH2 4.4Å; F309-W321 AromaticContact CZ-CH2 3.57Å; F309-W321 HydrophobicContact CZ-CH2 3.57Å; F309-W321 AromaticContact CZ-CZ2 3.93Å; F309-W321 HydrophobicContact CZ-CZ2 3.93Å; F309-W321 HydrophobicContact CZ-CZ3 4.17Å
310	T	85.4	Confident	83	Confident	38 Å²	38	76.9 Å²	76.9	23%	0.233	35%	0.354	C	S	.	.	S	Bend	trans	-56.6	145.7	170.1	-51.2	0	0	0	0	109.5	D307 H312 F313 R314	D307-T310 WeakPolarHBondContact O-CB 3.48Å; D307-T310 PolarHBondContact O-N 3.41Å; D307-T310 PolarHBondContact O-OG1 3.35Å; T310-H312 PolarHBondContact O-N 3.48Å; T310-F313 PolarHBondContact O-N 3.04Å; T310-R314 PolarHBondContact O-N 3.14Å
311	P	82.1	Confident	84.9	Confident	91 Å²	91	74.5 Å²	74.5	59%	0.591	34%	0.341	S	S	*	.	T	Hydrogen-bonded Turn	trans	-50.3	-29.1	-176.1	-31.4	35.9	0	0	0	115.2	R314	P311-R314 PolarHBondContact O-NE 3.5Å
312	H	80.7	Confident	86.6	Confident	73 Å²	73	70.4 Å²	70.4	34%	0.338	32%	0.316	S	S	.	.	T	Hydrogen-bonded Turn	trans	-73.3	-34.1	177.2	-61	-64.4	0	0	0	114.3	T310 M529	T310-H312 PolarHBondContact O-N 3.48Å; H312-M529 HydrophobicContact CB-CE 3.73Å; H312-M529 WeakPolarHBondContact O-CE 3.43Å
313	F	85.1	Confident	88	Confident	4 Å²	4	62.8 Å²	62.8	2%	0.018	29%	0.287	C	S	.	.	T	Hydrogen-bonded Turn	trans	-107.4	-20.2	-174.6	-67.3	-61.7	0	0	0	113.9	L308 T310 W315 T316 T317 Y452 P453 W525	L308-F313 CarbonylContact O-C 3.48Å; L308-F313 WeakPolarHBondContact O-CB 3.46Å; T310-F313 PolarHBondContact O-N 3.04Å; F313-W315 VanDerWaalsContact C-N 3.29Å; F313-W315 PolarHBondContact O-N 2.85Å; F313-W315 VanDerWaalsContact O-N 3.14Å; F313-T316 WeakPolarHBondContact O-CB 3.31Å; F313-T316 PolarHBondContact O-N 3.36Å; F313-T317 PolarHBondContact O-N 3.42Å; F313-T317 PolarHBondContact O-OG1 3.48Å; F313-Y452 HydrophobicContact CB-CE1 4.5Å; F313-Y452 HydrophobicContact CD1-CD1 4.33Å; F313-Y452 HydrophobicContact CD1-CE1 4.27Å; F313-Y452 HydrophobicContact CG-CE1 4.49Å; F313-P453 HydrophobicContact CZ-CG 4.12Å; F313-W525 AromaticContact CE1-CD1 3.98Å; F313-W525 AromaticContact CE1-NE1 3.42Å; F313-W525 AromaticContact CE2-CD1 3.98Å; F313-W525 AromaticContact CZ-CD1 3.26Å; F313-W525 HydrophobicContact CZ-CG 4.33Å; F313-W525 AromaticContact CZ-NE1 3.2Å
314	R	89.1	Confident	89.3	Confident	113 Å²	113	62.1 Å²	62.1	43%	0.426	28%	0.28	S	S	.	.	H	α-helix	trans	-51.4	-43.3	-173.2	66.3	-175.4	170.8	122.2	-4.7	114	T310 P311 L318	T310-R314 PolarHBondContact O-N 3.14Å; P311-R314 PolarHBondContact O-NE 3.5Å; R314-L318 WeakPolarHBondContact O-CB 3.29Å; R314-L318 VanDerWaalsContact O-CG 3.25Å; R314-L318 WeakPolarHBondContact O-CG 3.43Å; R314-L318 PolarHBondContact O-N 3.48Å
315	W	89.1	Confident	89.9	Confident	154 Å²	154	56.6 Å²	56.6	58%	0.583	26%	0.256	S	S	*	.	H	α-helix	trans	-71.1	-43.6	-179.6	-79.1	116.4	0	0	0	111.4	F313 T317 L318 L319	F313-W315 VanDerWaalsContact C-N 3.29Å; F313-W315 PolarHBondContact O-N 2.85Å; F313-W315 VanDerWaalsContact O-N 3.14Å; W315-T317 VanDerWaalsContact C-N 3.35Å; W315-T317 PolarHBondContact O-N 3.43Å; W315-L318 PolarHBondContact O-N 3.03Å; W315-L319 WeakPolarHBondContact O-CB 3.5Å; W315-L319 WeakPolarHBondContact O-CG 3.48Å; W315-L319 PolarHBondContact O-N 2.87Å
316	T	90.9	Very high	90.6	Very high	1 Å²	1	52 Å²	52	1%	0.006	23%	0.233	C	C	.	.	H	α-helix	trans	-59.8	-45.4	175	-47.2	0	0	0	0	111.4	F313 L319 L320 V451 L508 P509	F313-T316 WeakPolarHBondContact O-CB 3.31Å; F313-T316 PolarHBondContact O-N 3.36Å; T316-L319 PolarHBondContact O-N 3.38Å; T316-L320 HydrophobicContact CG2-CD1 4.07Å; T316-L320 VanDerWaalsContact O-CB 3.31Å; T316-L320 WeakPolarHBondContact O-CB 3.1Å; T316-L320 VanDerWaalsContact O-CG 3.25Å; T316-L320 WeakPolarHBondContact O-CG 3.26Å; T316-L320 PolarHBondContact O-N 3.29Å; T316-V451 HydrophobicContact CG2-CG1 3.52Å; T316-L508 HydrophobicContact CG2-CD2 4.44Å; T316-P509 WeakPolarHBondContact OG1-CG 3.32Å
317	T	93.1	Very high	91.1	Very high	0 Å²	0	42 Å²	42	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-62.6	-47.5	177.9	-54.6	0	0	0	0	111.7	L308 F313 W315 L320 W321 Y452	L308-T317 HydrophobicContact CB-CG2 4.24Å; L308-T317 PolarHBondContact O-OG1 2.81Å; F313-T317 PolarHBondContact O-N 3.42Å; F313-T317 PolarHBondContact O-OG1 3.48Å; W315-T317 VanDerWaalsContact C-N 3.35Å; W315-T317 PolarHBondContact O-N 3.43Å; T317-L320 PolarHBondContact O-N 2.98Å; T317-W321 HydrophobicContact CG2-CD2 4.44Å; T317-W321 HydrophobicContact CG2-CZ2 4.36Å; T317-W321 WeakPolarHBondContact O-CB 3.29Å; T317-W321 VanDerWaalsContact O-CG 3.27Å; T317-W321 PolarHBondContact O-N 2.93Å; T317-Y452 VanDerWaalsContact CA-OH 3.24Å; T317-Y452 WeakPolarHBondContact CA-OH 3.38Å; T317-Y452 WeakPolarHBondContact CB-OH 3.46Å; T317-Y452 PolarHBondContact OG1-OH 3.12Å
318	L	94.5	Very high	91.7	Very high	85 Å²	85	39.9 Å²	39.9	45%	0.445	18%	0.184	S	C	.	.	H	α-helix	trans	-64.7	-41.8	179	-71.7	173.2	0	0	0	112.5	R314 W315 W321 F322	R314-L318 WeakPolarHBondContact O-CB 3.29Å; R314-L318 VanDerWaalsContact O-CG 3.25Å; R314-L318 WeakPolarHBondContact O-CG 3.43Å; R314-L318 PolarHBondContact O-N 3.48Å; W315-L318 PolarHBondContact O-N 3.03Å; L318-W321 PolarHBondContact O-N 3.32Å; L318-F322 PolarHBondContact O-N 2.89Å; L318-F322 VanDerWaalsContact O-N 3.12Å
319	L	95.4	Very high	92.2	Very high	31 Å²	31	40.2 Å²	40.2	16%	0.162	19%	0.186	C	C	.	.	H	α-helix	trans	-64.8	-42.7	175.9	-69.6	172	0	0	0	111.2	W315 T316 F322 I323 A504 F507 L508	W315-L319 WeakPolarHBondContact O-CB 3.5Å; W315-L319 WeakPolarHBondContact O-CG 3.48Å; W315-L319 PolarHBondContact O-N 2.87Å; T316-L319 PolarHBondContact O-N 3.38Å; L319-F322 PolarHBondContact O-N 3.4Å; L319-I323 WeakPolarHBondContact O-CB 3.1Å; L319-I323 WeakPolarHBondContact O-CD1 3.42Å; L319-I323 VanDerWaalsContact O-CG1 3.23Å; L319-I323 WeakPolarHBondContact O-CG1 3.46Å; L319-I323 PolarHBondContact O-N 2.9Å; L319-A504 HydrophobicContact CD2-CB 3.82Å; L319-F507 HydrophobicContact CD1-CB 4.13Å; L319-L508 HydrophobicContact CB-CD2 3.92Å; L319-L508 HydrophobicContact CD1-CD2 4.31Å
320	L	94.8	Very high	92.6	Very high	0 Å²	0	36.1 Å²	36.1	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-66	-40.7	176.9	-75.3	176.2	0	0	0	112.3	T316 T317 F322 I323 W324 Y447 T448 Y452 L508	T316-L320 HydrophobicContact CG2-CD1 4.07Å; T316-L320 VanDerWaalsContact O-CB 3.31Å; T316-L320 WeakPolarHBondContact O-CB 3.1Å; T316-L320 VanDerWaalsContact O-CG 3.25Å; T316-L320 WeakPolarHBondContact O-CG 3.26Å; T316-L320 PolarHBondContact O-N 3.29Å; T317-L320 PolarHBondContact O-N 2.98Å; L320-F322 VanDerWaalsContact C-N 3.28Å; L320-F322 PolarHBondContact O-N 3.47Å; L320-I323 HydrophobicContact CD2-CD1 4.46Å; L320-I323 PolarHBondContact O-N 3.41Å; L320-W324 WeakPolarHBondContact O-CB 3.43Å; L320-W324 PolarHBondContact O-N 2.95Å; L320-Y447 HydrophobicContact CD1-CE1 4.43Å; L320-Y447 HydrophobicContact CD2-CD1 3.73Å; L320-Y447 HydrophobicContact CD2-CE1 3.82Å; L320-Y447 HydrophobicContact CG-CE1 4.5Å; L320-T448 HydrophobicContact CD1-CG2 4.48Å; L320-Y452 HydrophobicContact CD1-CE2 3.85Å; L320-L508 HydrophobicContact CD2-CD2 4.2Å; L320-L508 HydrophobicContact CG-CD2 4.18Å
321	W	96	Very high	93.1	Very high	48 Å²	48	34.7 Å²	34.7	18%	0.182	16%	0.158	C	C	.	.	H	α-helix	trans	-56.3	-45.8	173.7	-78.8	15.4	0	0	0	111.4	M305 F309 T317 L318 F325 T463 M467	M305-W321 HydrophobicContact CE-CH2 4.19Å; M305-W321 HydrophobicContact CE-CZ2 4.08Å; F309-W321 HydrophobicContact CE1-CH2 4.46Å; F309-W321 HydrophobicContact CE2-CH2 4.4Å; F309-W321 AromaticContact CZ-CH2 3.57Å; F309-W321 HydrophobicContact CZ-CH2 3.57Å; F309-W321 AromaticContact CZ-CZ2 3.93Å; F309-W321 HydrophobicContact CZ-CZ2 3.93Å; F309-W321 HydrophobicContact CZ-CZ3 4.17Å; T317-W321 HydrophobicContact CG2-CD2 4.44Å; T317-W321 HydrophobicContact CG2-CZ2 4.36Å; T317-W321 WeakPolarHBondContact O-CB 3.29Å; T317-W321 VanDerWaalsContact O-CG 3.27Å; T317-W321 PolarHBondContact O-N 2.93Å; L318-W321 PolarHBondContact O-N 3.32Å; W321-F325 VanDerWaalsContact O-CB 3.28Å; W321-F325 WeakPolarHBondContact O-CB 3.41Å; W321-F325 PolarHBondContact O-N 3.44Å; W321-T463 HydrophobicContact CZ2-CG2 4.41Å; W321-T463 PolarHBondContact NE1-OG1 3.37Å; W321-M467 HydrophobicContact CB-CB 4.33Å; W321-M467 HydrophobicContact CB-CG 4.06Å; W321-M467 HydrophobicContact CD2-CE 4.05Å; W321-M467 HydrophobicContact CE3-CE 3.54Å; W321-M467 HydrophobicContact CG-CB 4.42Å; W321-M467 HydrophobicContact CZ3-CE 3.94Å; W321-M467 VanDerWaalsContact O-CG 3.26Å; W321-M467 WeakPolarHBondContact O-CG 3.25Å
322	F	97.1	Very high	93.7	Very high	69 Å²	69	30.9 Å²	30.9	30%	0.303	13%	0.132	S	C	.	.	H	α-helix	trans	-67.1	-41.2	176.8	-175.2	-111.9	0	0	0	112.6	L318 L319 L320 W324 F325 S326 L500 A501 A504	L318-F322 PolarHBondContact O-N 2.89Å; L318-F322 VanDerWaalsContact O-N 3.12Å; L319-F322 PolarHBondContact O-N 3.4Å; L320-F322 VanDerWaalsContact C-N 3.28Å; L320-F322 PolarHBondContact O-N 3.47Å; F322-W324 PolarHBondContact O-N 3.43Å; F322-F325 WeakPolarHBondContact O-CB 3.45Å; F322-F325 PolarHBondContact O-N 3.05Å; F322-S326 WeakPolarHBondContact O-CB 3.47Å; F322-S326 PolarHBondContact O-N 2.9Å; F322-S326 PolarHBondContact O-OG 3.14Å; F322-S326 VanDerWaalsContact O-OG 3.1Å; F322-L500 HydrophobicContact CE1-CB 3.78Å; F322-L500 HydrophobicContact CZ-CB 3.8Å; F322-A501 HydrophobicContact CE1-CB 4.16Å; F322-A504 HydrophobicContact CD1-CB 3.92Å; F322-A504 HydrophobicContact CE1-CB 4.45Å
323	I	96.8	Very high	94.3	Very high	0 Å²	0	27.4 Å²	27.4	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-61.5	-46.2	176.8	-71.9	162.2	0	0	0	111.1	L319 L320 S326 N327 M403 F407 A504 L508	L319-I323 WeakPolarHBondContact O-CB 3.1Å; L319-I323 WeakPolarHBondContact O-CD1 3.42Å; L319-I323 VanDerWaalsContact O-CG1 3.23Å; L319-I323 WeakPolarHBondContact O-CG1 3.46Å; L319-I323 PolarHBondContact O-N 2.9Å; L320-I323 HydrophobicContact CD2-CD1 4.46Å; L320-I323 PolarHBondContact O-N 3.41Å; I323-S326 PolarHBondContact O-N 3.38Å; I323-N327 VanDerWaalsContact O-CB 3.26Å; I323-N327 WeakPolarHBondContact O-CB 3.26Å; I323-N327 PolarHBondContact O-N 3.43Å; I323-M403 HydrophobicContact CG2-SD 4.45Å; I323-F407 HydrophobicContact CG2-CE2 3.97Å; I323-F407 HydrophobicContact CG2-CZ 4.16Å; I323-A504 HydrophobicContact CD1-CB 4.5Å; I323-A504 HydrophobicContact CG1-CB 4.22Å; I323-L508 HydrophobicContact CD1-CD1 3.75Å; I323-L508 HydrophobicContact CD1-CD2 4.29Å; I323-L508 HydrophobicContact CD1-CG 4.1Å
324	W	96.6	Very high	94.8	Very high	1 Å²	1	27.4 Å²	27.4	0%	0.004	12%	0.116	C	C	.	.	H	α-helix	trans	-66.3	-40.5	177.9	-85	81.4	0	0	0	112.4	L320 F322 N327 A328 A444 Y445 T448 L461 C464 A468	L320-W324 WeakPolarHBondContact O-CB 3.43Å; L320-W324 PolarHBondContact O-N 2.95Å; F322-W324 PolarHBondContact O-N 3.43Å; W324-N327 PolarHBondContact O-N 3.33Å; W324-A328 PolarHBondContact O-N 2.9Å; W324-A444 HydrophobicContact CZ2-CB 4.41Å; W324-Y445 HydrophobicContact CE3-CE2 4.31Å; W324-Y445 AromaticContact CH2-CD1 3.81Å; W324-Y445 HydrophobicContact CH2-CD1 3.81Å; W324-Y445 AromaticContact CH2-CD2 3.37Å; W324-Y445 HydrophobicContact CH2-CD2 3.37Å; W324-Y445 AromaticContact CH2-CE1 3.66Å; W324-Y445 HydrophobicContact CH2-CE1 3.66Å; W324-Y445 AromaticContact CH2-CE2 3.11Å; W324-Y445 HydrophobicContact CH2-CE2 3.11Å; W324-Y445 AromaticContact CH2-CG 3.71Å; W324-Y445 HydrophobicContact CH2-CG 3.71Å; W324-Y445 AromaticContact CH2-CZ 3.33Å; W324-Y445 HydrophobicContact CZ2-CD2 4.05Å; W324-Y445 HydrophobicContact CZ2-CE2 4.18Å; W324-Y445 HydrophobicContact CZ2-CG 4.25Å; W324-Y445 AromaticContact CZ3-CD2 3.88Å; W324-Y445 HydrophobicContact CZ3-CD2 3.88Å; W324-Y445 HydrophobicContact CZ3-CE1 4.2Å; W324-Y445 AromaticContact CZ3-CE2 3.18Å; W324-Y445 HydrophobicContact CZ3-CE2 3.18Å; W324-Y445 AromaticContact CZ3-CZ 3.43Å; W324-Y445 VanDerWaalsContact CZ3-CZ 3.43Å; W324-T448 PolarHBondContact NE1-OG1 2.84Å; W324-L461 HydrophobicContact CH2-CD1 3.65Å; W324-L461 HydrophobicContact CZ2-CD1 3.48Å; W324-L461 VanDerWaalsContact CZ2-CD1 3.48Å; W324-C464 HydrophobicContact CB-CB 4.29Å; W324-C464 WeakPolarHBondContact CB-O 3.44Å; W324-C464 HydrophobicContact CD2-CB 3.83Å; W324-C464 HydrophobicContact CG-CB 3.65Å; W324-A468 HydrophobicContact CB-CB 4.19Å; W324-A468 HydrophobicContact CE3-CB 3.76Å; W324-A468 WeakPolarHBondContact O-CB 3.41Å
325	F	97.2	Very high	94.9	Very high	41 Å²	41	22.4 Å²	22.4	18%	0.18	10%	0.098	C	C	.	.	H	α-helix	trans	-53.3	-56.5	170.2	177.4	-91.3	0	0	0	110.9	W321 F322 N327 A328 F329 M467 V470 G471 I474	W321-F325 VanDerWaalsContact O-CB 3.28Å; W321-F325 WeakPolarHBondContact O-CB 3.41Å; W321-F325 PolarHBondContact O-N 3.44Å; F322-F325 WeakPolarHBondContact O-CB 3.45Å; F322-F325 PolarHBondContact O-N 3.05Å; F325-N327 PolarHBondContact O-N 2.94Å; F325-A328 PolarHBondContact O-N 3.27Å; F325-F329 HydrophobicContact CE1-CB 4.32Å; F325-F329 HydrophobicContact CE1-CG 4.39Å; F325-F329 WeakPolarHBondContact O-CB 3.39Å; F325-F329 PolarHBondContact O-N 3.11Å; F325-M467 HydrophobicContact CB-CG 3.95Å; F325-M467 HydrophobicContact CD2-CG 4.47Å; F325-M467 HydrophobicContact CD2-SD 4.46Å; F325-V470 HydrophobicContact CD2-CB 4.44Å; F325-V470 HydrophobicContact CD2-CG1 4.49Å; F325-V470 HydrophobicContact CE2-CG1 4.17Å; F325-G471 VanDerWaalsContact CD2-CA 3.49Å; F325-I474 HydrophobicContact CE2-CD1 3.97Å; F325-I474 HydrophobicContact CZ-CD1 4.09Å
326	S	97.2	Very high	95.1	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-64.8	-38	-176.9	-63.1	0	0	0	0	112.6	F322 I323 S330 C497	F322-S326 WeakPolarHBondContact O-CB 3.47Å; F322-S326 PolarHBondContact O-N 2.9Å; F322-S326 PolarHBondContact O-OG 3.14Å; F322-S326 VanDerWaalsContact O-OG 3.1Å; I323-S326 PolarHBondContact O-N 3.38Å; S326-S330 VanDerWaalsContact O-CB 3.24Å; S326-S330 WeakPolarHBondContact O-CB 3.08Å; S326-S330 PolarHBondContact O-N 3.39Å; S326-S330 PolarHBondContact O-OG 3.03Å; S326-S330 VanDerWaalsContact O-OG 3.12Å; S326-C497 PolarHBondContact OG-SG 2.83Å
327	N	95.8	Very high	95.1	Very high	1 Å²	1	15.6 Å²	15.6	1%	0.005	7%	0.073	C	C	.	.	H	α-helix	trans	-59.7	-51.6	175.6	-102.2	-19.4	0	0	0	111.5	I323 W324 F325 Y331 F407 G440 F441	I323-N327 VanDerWaalsContact O-CB 3.26Å; I323-N327 WeakPolarHBondContact O-CB 3.26Å; I323-N327 PolarHBondContact O-N 3.43Å; W324-N327 PolarHBondContact O-N 3.33Å; F325-N327 PolarHBondContact O-N 2.94Å; N327-Y331 WeakPolarHBondContact O-CB 3.49Å; N327-Y331 PolarHBondContact O-N 2.79Å; N327-F407 HydrophobicContact CB-CZ 4.28Å; N327-F407 VanDerWaalsContact CG-CZ 3.47Å; N327-F407 VanDerWaalsContact OD1-CE1 3.24Å; N327-F407 WeakPolarHBondContact OD1-CE1 3.37Å; N327-F407 WeakPolarHBondContact OD1-CZ 3.4Å; N327-G440 PolarHBondContact ND2-O 3.31Å; N327-F441 HydrophobicContact CB-CD2 3.77Å; N327-F441 HydrophobicContact CB-CE2 4.26Å
328	A	95.4	Very high	94.9	Very high	1 Å²	1	15.6 Å²	15.6	1%	0.008	7%	0.073	C	C	.	.	H	α-helix	trans	-69.3	-43.7	178.7	0	0	0	0	0	112.3	W324 F325 S330 Y331 Y332 F441 A468 A472	W324-A328 PolarHBondContact O-N 2.9Å; F325-A328 PolarHBondContact O-N 3.27Å; A328-S330 VanDerWaalsContact C-N 3.3Å; A328-S330 PolarHBondContact O-N 3.4Å; A328-Y331 PolarHBondContact O-N 3.23Å; A328-Y332 HydrophobicContact CB-CD2 4.17Å; A328-Y332 HydrophobicContact CB-CE2 4.2Å; A328-Y332 WeakPolarHBondContact O-CD2 3.14Å; A328-Y332 PolarHBondContact O-N 2.91Å; A328-F441 HydrophobicContact CB-CE2 4.09Å; A328-A468 HydrophobicContact CB-CB 3.69Å; A328-A468 WeakPolarHBondContact CB-O 3.44Å; A328-A472 HydrophobicContact CB-CB 4.42Å
329	F	96.7	Very high	94.6	Very high	7 Å²	7	11.6 Å²	11.6	3%	0.031	5%	0.052	C	C	.	.	H	α-helix	trans	-53.8	-48.5	176.9	176.7	-108.5	0	0	0	111.1	F325 G333 G471 I474 T475 I478 V493 Y494 C497	F325-F329 HydrophobicContact CE1-CB 4.32Å; F325-F329 HydrophobicContact CE1-CG 4.39Å; F325-F329 WeakPolarHBondContact O-CB 3.39Å; F325-F329 PolarHBondContact O-N 3.11Å; F329-G333 VanDerWaalsContact O-CA 3.28Å; F329-G333 WeakPolarHBondContact O-CA 3.46Å; F329-G333 PolarHBondContact O-N 3.04Å; F329-G471 WeakPolarHBondContact CD2-O 3.29Å; F329-I474 HydrophobicContact CE2-CG2 4.17Å; F329-T475 PolarHBondContact O-OG1 3.2Å; F329-I478 HydrophobicContact CE2-CB 4.26Å; F329-I478 HydrophobicContact CE2-CG1 3.89Å; F329-I478 HydrophobicContact CZ-CB 4.24Å; F329-I478 HydrophobicContact CZ-CG1 4.01Å; F329-I478 HydrophobicContact CZ-CG2 4.12Å; F329-V493 HydrophobicContact CE1-CG1 4.14Å; F329-V493 HydrophobicContact CZ-CG1 3.88Å; F329-Y494 AromaticContact CD1-CD1 3.75Å; F329-Y494 HydrophobicContact CD1-CD1 3.75Å; F329-Y494 AromaticContact CD1-CE1 3.81Å; F329-Y494 HydrophobicContact CD1-CE1 3.81Å; F329-Y494 HydrophobicContact CD2-CE1 4.34Å; F329-Y494 AromaticContact CE1-CD1 3.3Å; F329-Y494 HydrophobicContact CE1-CD1 3.3Å; F329-Y494 AromaticContact CE1-CE1 3.4Å; F329-Y494 HydrophobicContact CE1-CE1 3.4Å; F329-Y494 HydrophobicContact CE1-CG 4.27Å; F329-Y494 AromaticContact CE2-CE1 3.97Å; F329-Y494 HydrophobicContact CE2-CE1 3.97Å; F329-Y494 HydrophobicContact CG-CE1 4.27Å; F329-Y494 AromaticContact CZ-CD1 3.84Å; F329-Y494 HydrophobicContact CZ-CD1 3.84Å; F329-Y494 AromaticContact CZ-CE1 3.48Å; F329-Y494 HydrophobicContact CZ-CE1 3.48Å; F329-Y494 VanDerWaalsContact CZ-CE1 3.48Å; F329-C497 HydrophobicContact CD1-CB 4.26Å; F329-C497 HydrophobicContact CE1-CB 4.18Å
330	S	96.3	Very high	94	Very high	0 Å²	0	10.3 Å²	10.3	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-81.7	-34.1	-177.4	-61.7	0	0	0	0	113.9	S326 A328 L334 C498	S326-S330 VanDerWaalsContact O-CB 3.24Å; S326-S330 WeakPolarHBondContact O-CB 3.08Å; S326-S330 PolarHBondContact O-N 3.39Å; S326-S330 PolarHBondContact O-OG 3.03Å; S326-S330 VanDerWaalsContact O-OG 3.12Å; A328-S330 VanDerWaalsContact C-N 3.3Å; A328-S330 PolarHBondContact O-N 3.4Å; S330-L334 WeakPolarHBondContact O-CB 3.39Å; S330-L334 PolarHBondContact O-N 3.37Å; S330-C498 VanDerWaalsContact CB-SG 3.56Å; S330-C498 PolarHBondContact OG-SG 3.3Å
331	Y	95.3	Very high	93.5	Very high	9 Å²	9	11.3 Å²	11.3	4%	0.035	5%	0.05	C	C	.	.	H	α-helix	trans	-63	-60.4	175.2	175.2	-99	0	0	0	110.7	W217 N327 A328 G333 L334 V335 E383 I437	W217-Y331 HydrophobicContact CZ2-CE1 4.09Å; W217-Y331 AromaticContact NE1-CZ 3.69Å; W217-Y331 PolarHBondContact NE1-OH 3.5Å; N327-Y331 WeakPolarHBondContact O-CB 3.49Å; N327-Y331 PolarHBondContact O-N 2.79Å; A328-Y331 PolarHBondContact O-N 3.23Å; Y331-G333 VanDerWaalsContact C-N 3.28Å; Y331-G333 PolarHBondContact O-N 3.05Å; Y331-L334 PolarHBondContact O-N 2.95Å; Y331-V335 HydrophobicContact CE1-CG2 4.28Å; Y331-V335 VanDerWaalsContact O-CG2 3.24Å; Y331-V335 WeakPolarHBondContact O-CG2 3.21Å; Y331-V335 PolarHBondContact O-N 3.45Å; Y331-V335 VanDerWaalsContact O-N 3.1Å; Y331-E383 PolarHBondContact OH-OE1 3.42Å; Y331-I437 HydrophobicContact CD2-CG2 4.15Å
332	Y	94.9	Very high	92.9	Very high	11 Å²	11	9.4 Å²	9.4	4%	0.043	4%	0.043	C	C	.	.	H	α-helix	trans	-66.9	-33.2	179.8	-64.4	-64.1	0	0	0	111.7	M101 F130 W217 A328 V335 L336 R469 A472	M101-Y332 HydrophobicContact CB-CE1 4.31Å; M101-Y332 HydrophobicContact CE-CD1 3.84Å; M101-Y332 HydrophobicContact CE-CE1 3.68Å; M101-Y332 HydrophobicContact CG-CE1 4.15Å; F130-Y332 HydrophobicContact CE1-CD1 4.33Å; F130-Y332 HydrophobicContact CE1-CD2 4.14Å; F130-Y332 HydrophobicContact CE1-CE1 4.4Å; F130-Y332 HydrophobicContact CE1-CE2 4.23Å; F130-Y332 HydrophobicContact CE1-CG 4.21Å; F130-Y332 HydrophobicContact CZ-CD1 4.06Å; F130-Y332 HydrophobicContact CZ-CD2 4.2Å; F130-Y332 AromaticContact CZ-CG 3.88Å; F130-Y332 HydrophobicContact CZ-CG 3.88Å; W217-Y332 HydrophobicContact CH2-CE1 4.49Å; W217-Y332 HydrophobicContact CZ2-CE1 4.22Å; A328-Y332 HydrophobicContact CB-CD2 4.17Å; A328-Y332 HydrophobicContact CB-CE2 4.2Å; A328-Y332 WeakPolarHBondContact O-CD2 3.14Å; A328-Y332 PolarHBondContact O-N 2.91Å; Y332-V335 PolarHBondContact O-N 3.29Å; Y332-L336 WeakPolarHBondContact O-CG 3.28Å; Y332-L336 PolarHBondContact O-N 3.14Å; Y332-R469 PolarHBondContact OH-NH1 3.43Å; Y332-A472 HydrophobicContact CD2-CB 3.51Å; Y332-A472 HydrophobicContact CE2-CB 3.91Å; Y332-A472 HydrophobicContact CG-CB 4.38Å
333	G	94	Very high	91.8	Very high	0 Å²	0	7.2 Å²	7.2	0%	0	3%	0.034	C	C	.	.	H	α-helix	trans	-61.4	-44.6	174.4	0	0	0	0	0	112.3	F329 Y331 L336 L337 T475 Y494	F329-G333 VanDerWaalsContact O-CA 3.28Å; F329-G333 WeakPolarHBondContact O-CA 3.46Å; F329-G333 PolarHBondContact O-N 3.04Å; Y331-G333 VanDerWaalsContact C-N 3.28Å; Y331-G333 PolarHBondContact O-N 3.05Å; G333-L336 PolarHBondContact O-N 2.94Å; G333-L337 WeakPolarHBondContact O-CB 2.99Å; G333-L337 PolarHBondContact O-N 3.36Å; G333-T475 WeakPolarHBondContact CA-OG1 3.46Å; G333-T475 PolarHBondContact N-OG1 2.94Å; G333-Y494 WeakPolarHBondContact CA-OH 3.47Å
334	L	93.7	Very high	90.4	Very high	4 Å²	4	8.3 Å²	8.3	2%	0.021	4%	0.043	C	C	.	.	H	α-helix	trans	-63.7	-40.7	174.7	-171.9	75	0	0	0	111.4	S330 Y331 L336 L337 T338 F410 L430 A433 R434 I437	S330-L334 WeakPolarHBondContact O-CB 3.39Å; S330-L334 PolarHBondContact O-N 3.37Å; Y331-L334 PolarHBondContact O-N 2.95Å; L334-L336 PolarHBondContact O-N 3.33Å; L334-L337 PolarHBondContact O-N 3.1Å; L334-T338 WeakPolarHBondContact O-CB 3.41Å; L334-T338 PolarHBondContact O-N 3.16Å; L334-T338 PolarHBondContact O-OG1 3.34Å; L334-F410 HydrophobicContact CB-CE2 4.16Å; L334-F410 HydrophobicContact CD1-CE2 4.04Å; L334-F410 HydrophobicContact CD2-CE2 4.04Å; L334-F410 HydrophobicContact CG-CE2 4.31Å; L334-L430 HydrophobicContact CD1-CD2 3.68Å; L334-A433 HydrophobicContact CD1-CB 4.31Å; L334-A433 HydrophobicContact CD2-CB 4.02Å; L334-R434 HydrophobicContact CD2-CB 3.52Å; L334-R434 HydrophobicContact CD2-CG 4.07Å; L334-I437 HydrophobicContact CD2-CG2 4.23Å
335	V	93.2	Very high	88.4	Confident	7 Å²	7	10.1 Å²	10.1	4%	0.042	6%	0.062	C	C	.	.	H	α-helix	trans	-59.5	-46.4	178.1	-177.4	0	0	0	0	111.4	M102 S105 Y331 Y332	M102-V335 HydrophobicContact CE-CG1 4.19Å; M102-V335 HydrophobicContact SD-CG1 3.86Å; S105-V335 WeakPolarHBondContact CB-O 3.4Å; Y331-V335 HydrophobicContact CE1-CG2 4.28Å; Y331-V335 VanDerWaalsContact O-CG2 3.24Å; Y331-V335 WeakPolarHBondContact O-CG2 3.21Å; Y331-V335 PolarHBondContact O-N 3.45Å; Y331-V335 VanDerWaalsContact O-N 3.1Å; Y332-V335 PolarHBondContact O-N 3.29Å
336	L	92.3	Very high	86.3	Confident	8 Å²	8	13.1 Å²	13.1	4%	0.042	8%	0.079	C	C	.	.	H	α-helix	trans	-71.7	-43	177.6	-65.2	176.9	0	0	0	112.1	T126 Y332 G333 L334 T338 T339 E340 T475 P476 A479	T126-L336 HydrophobicContact CG2-CD2 4.22Å; Y332-L336 WeakPolarHBondContact O-CG 3.28Å; Y332-L336 PolarHBondContact O-N 3.14Å; G333-L336 PolarHBondContact O-N 2.94Å; L334-L336 PolarHBondContact O-N 3.33Å; L336-T338 VanDerWaalsContact C-N 3.25Å; L336-T338 PolarHBondContact O-N 2.99Å; L336-T339 PolarHBondContact O-N 3.37Å; L336-T339 PolarHBondContact O-OG1 2.88Å; L336-T339 VanDerWaalsContact O-OG1 3.08Å; L336-E340 WeakPolarHBondContact O-CG 3.5Å; L336-T475 HydrophobicContact CD1-CG2 4.13Å; L336-P476 HydrophobicContact CD1-CB 3.79Å; L336-P476 HydrophobicContact CD1-CG 3.8Å; L336-A479 HydrophobicContact CB-CB 3.86Å
337	L	90.5	Very high	84.1	Confident	4 Å²	4	17 Å²	17	2%	0.021	10%	0.103	C	C	.	.	H	α-helix	trans	-62.9	-33.3	-179.6	179.7	65.4	0	0	0	112.1	G333 L334 T339 E340 L341 L483 T490 L491 Y494	G333-L337 WeakPolarHBondContact O-CB 2.99Å; G333-L337 PolarHBondContact O-N 3.36Å; L334-L337 PolarHBondContact O-N 3.1Å; L337-T339 PolarHBondContact O-N 2.99Å; L337-E340 PolarHBondContact O-N 3.15Å; L337-L341 WeakPolarHBondContact O-CB 3.41Å; L337-L341 PolarHBondContact O-N 3.29Å; L337-L483 HydrophobicContact CD1-CD1 3.48Å; L337-L483 VanDerWaalsContact CD1-CD1 3.48Å; L337-L483 HydrophobicContact CD1-CD2 3.9Å; L337-L483 HydrophobicContact CD1-CG 4.3Å; L337-T490 HydrophobicContact CD1-CG2 4.23Å; L337-L491 HydrophobicContact CD2-CD2 3.89Å; L337-Y494 HydrophobicContact CD2-CD2 4.33Å; L337-Y494 HydrophobicContact CD2-CE2 4.38Å
338	T	89.4	Confident	82	Confident	1 Å²	1	19.3 Å²	19.3	1%	0.006	12%	0.119	C	C	.	.	H	α-helix	trans	-59.5	-46.1	-177.7	-64.9	0	0	0	0	111.6	L334 L336 F342 L376 T379 L430	L334-T338 WeakPolarHBondContact O-CB 3.41Å; L334-T338 PolarHBondContact O-N 3.16Å; L334-T338 PolarHBondContact O-OG1 3.34Å; L336-T338 VanDerWaalsContact C-N 3.25Å; L336-T338 PolarHBondContact O-N 2.99Å; T338-F342 HydrophobicContact CG2-CD2 3.83Å; T338-F342 HydrophobicContact CG2-CE2 3.34Å; T338-F342 HydrophobicContact CG2-CZ 4.23Å; T338-F342 WeakPolarHBondContact O-CD2 3.12Å; T338-F342 WeakPolarHBondContact O-CG 3.45Å; T338-F342 PolarHBondContact O-N 3.49Å; T338-L376 HydrophobicContact CG2-CD1 3.82Å; T338-T379 HydrophobicContact CG2-CG2 4.48Å; T338-L430 HydrophobicContact CG2-CD1 4.09Å
339	T	87.7	Confident	79.5	Confident	0 Å²	0	22.9 Å²	22.9	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-69.4	-43.1	-179.2	50.3	0	0	0	0	111.6	S105 L336 L337 L341 F342 Q343 L368 L376	S105-T339 WeakPolarHBondContact O-CB 3.33Å; S105-T339 WeakPolarHBondContact O-CG2 3.48Å; S105-T339 PolarHBondContact O-OG1 3.21Å; L336-T339 PolarHBondContact O-N 3.37Å; L336-T339 PolarHBondContact O-OG1 2.88Å; L336-T339 VanDerWaalsContact O-OG1 3.08Å; L337-T339 PolarHBondContact O-N 2.99Å; T339-L341 VanDerWaalsContact C-N 3.35Å; T339-L341 PolarHBondContact O-N 3.15Å; T339-F342 PolarHBondContact O-N 2.84Å; T339-Q343 WeakPolarHBondContact O-CG 3.26Å; T339-Q343 PolarHBondContact O-N 2.74Å; T339-L368 HydrophobicContact CG2-CD2 4.26Å; T339-L376 HydrophobicContact CG2-CD1 3.96Å; T339-L376 HydrophobicContact CG2-CD2 4.01Å
340	E	83.9	Confident	77.1	Confident	5 Å²	5	27.9 Å²	27.9	2%	0.023	17%	0.169	C	C	.	.	H	α-helix	trans	-65	-36.5	177.4	-57.4	-72.7	169.8	0	0	112.3	L336 L337 Q343 A344 Q480 L483	L336-E340 WeakPolarHBondContact O-CG 3.5Å; L337-E340 PolarHBondContact O-N 3.15Å; E340-Q343 PolarHBondContact O-N 2.93Å; E340-A344 WeakPolarHBondContact O-CB 3.44Å; E340-A344 PolarHBondContact O-N 3.41Å; E340-Q480 PolarHBondContact OE1-NE2 2.88Å; E340-L483 HydrophobicContact CB-CD2 3.39Å; E340-L483 HydrophobicContact CG-CD2 4.22Å
341	L	83.9	Confident	74.4	Confident	20 Å²	20	32.7 Å²	32.7	11%	0.105	20%	0.203	C	C	.	.	H	α-helix	trans	-73.7	-30.7	-179.4	-169.4	59.2	0	0	0	112.4	L337 T339 A344 G345 L417 L426 V487	L337-L341 WeakPolarHBondContact O-CB 3.41Å; L337-L341 PolarHBondContact O-N 3.29Å; T339-L341 VanDerWaalsContact C-N 3.35Å; T339-L341 PolarHBondContact O-N 3.15Å; L341-A344 PolarHBondContact O-N 2.83Å; L341-G345 PolarHBondContact O-N 2.92Å; L341-G345 VanDerWaalsContact O-N 3.16Å; L341-L417 HydrophobicContact CD2-CD1 4.25Å; L341-L426 HydrophobicContact CD2-CD1 3.56Å; L341-L426 HydrophobicContact CG-CD1 4.14Å; L341-L426 HydrophobicContact CG-CD2 4.24Å; L341-V487 HydrophobicContact CD1-CG1 4.24Å
342	F	83.3	Confident	71.7	Confident	8 Å²	8	38 Å²	38	4%	0.035	24%	0.242	C	C	.	.	H	α-helix	trans	-70.7	-38.3	171.5	-71.3	-47.8	0	0	0	112	T338 T339 A344 G345 D372 D375 T379 L426 L430	T338-F342 HydrophobicContact CG2-CD2 3.83Å; T338-F342 HydrophobicContact CG2-CE2 3.34Å; T338-F342 HydrophobicContact CG2-CZ 4.23Å; T338-F342 WeakPolarHBondContact O-CD2 3.12Å; T338-F342 WeakPolarHBondContact O-CG 3.45Å; T338-F342 PolarHBondContact O-N 3.49Å; T339-F342 PolarHBondContact O-N 2.84Å; F342-A344 VanDerWaalsContact C-N 3.32Å; F342-A344 PolarHBondContact O-N 3.42Å; F342-G345 PolarHBondContact O-N 3.12Å; F342-G345 VanDerWaalsContact O-N 3.08Å; F342-D372 HydrophobicContact CB-CB 4.32Å; F342-D375 HydrophobicContact CD1-CB 4.42Å; F342-D375 HydrophobicContact CD2-CB 4.32Å; F342-D375 HydrophobicContact CE1-CB 3.87Å; F342-D375 HydrophobicContact CE2-CB 3.72Å; F342-D375 HydrophobicContact CZ-CB 3.5Å; F342-D375 VanDerWaalsContact CZ-CB 3.5Å; F342-T379 HydrophobicContact CZ-CG2 4.36Å; F342-L426 HydrophobicContact CD1-CD2 3.87Å; F342-L426 HydrophobicContact CE1-CD2 3.78Å; F342-L426 HydrophobicContact CE1-CG 4Å; F342-L430 HydrophobicContact CE1-CD1 4.27Å; F342-L430 HydrophobicContact CE2-CD1 4.29Å; F342-L430 HydrophobicContact CZ-CD1 3.79Å
343	Q	74.3	Confident	69.1	Low	24 Å²	24	48 Å²	48	11%	0.112	28%	0.28	C	S	.	.	H	α-helix	trans	-64.7	-36.3	171.2	-68.9	175.2	-60	0	0	112.3	P109 T339 E340 G345 E366 L368	P109-Q343 VanDerWaalsContact CB-OE1 3.27Å; T339-Q343 WeakPolarHBondContact O-CG 3.26Å; T339-Q343 PolarHBondContact O-N 2.74Å; E340-Q343 PolarHBondContact O-N 2.93Å; Q343-G345 PolarHBondContact O-N 3.15Å; Q343-E366 PolarHBondContact NE2-O 3.37Å; Q343-L368 HydrophobicContact CG-CD1 3.88Å; Q343-L368 HydrophobicContact CG-CG 4.49Å
344	A	66.8	Low	66.3	Low	23 Å²	23	57.6 Å²	57.6	19%	0.19	32%	0.321	C	S	.	.	T	Hydrogen-bonded Turn	trans	-75.8	-3.5	174.3	0	0	0	0	0	113.7	E340 L341 F342 D346 V347	E340-A344 WeakPolarHBondContact O-CB 3.44Å; E340-A344 PolarHBondContact O-N 3.41Å; L341-A344 PolarHBondContact O-N 2.83Å; F342-A344 VanDerWaalsContact C-N 3.32Å; F342-A344 PolarHBondContact O-N 3.42Å; A344-D346 PolarHBondContact O-N 3.18Å; A344-V347 WeakPolarHBondContact O-CB 3.42Å; A344-V347 VanDerWaalsContact O-CG2 3.24Å; A344-V347 WeakPolarHBondContact O-CG2 3.25Å; A344-V347 PolarHBondContact O-N 3.47Å; A344-V347 VanDerWaalsContact O-N 3.08Å
345	G	54.9	Low	63.5	Low	38 Å²	38	66.6 Å²	66.6	39%	0.392	36%	0.36	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.3	-12.1	-165.5	0	0	0	0	0	116.5	L341 F342 Q343	L341-G345 PolarHBondContact O-N 2.92Å; L341-G345 VanDerWaalsContact O-N 3.16Å; F342-G345 PolarHBondContact O-N 3.12Å; F342-G345 VanDerWaalsContact O-N 3.08Å; Q343-G345 PolarHBondContact O-N 3.15Å
346	D	53.7	Low	60.8	Low	104 Å²	104	71.5 Å²	71.5	56%	0.556	40%	0.401	S	S	*	.	T	Hydrogen-bonded Turn	trans	-86.4	-9.2	175.9	-102.5	-22.2	0	0	0	114.8	A344 C348 S349	A344-D346 PolarHBondContact O-N 3.18Å; D346-C348 PolarHBondContact O-N 3.17Å; D346-C348 VanDerWaalsContact O-N 3.17Å; D346-S349 PolarHBondContact O-N 3.4Å; D346-S349 PolarHBondContact O-OG 3.11Å; D346-S349 VanDerWaalsContact O-OG 3.09Å; D346-S349 PolarHBondContact OD1-OG 3.08Å
347	V	50.9	Low	58.2	Low	81 Å²	81	76.9 Å²	76.9	49%	0.491	43%	0.434	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63.4	-27.8	-179	177.5	0	0	0	0	112	A344	A344-V347 WeakPolarHBondContact O-CB 3.42Å; A344-V347 VanDerWaalsContact O-CG2 3.24Å; A344-V347 WeakPolarHBondContact O-CG2 3.25Å; A344-V347 PolarHBondContact O-N 3.47Å; A344-V347 VanDerWaalsContact O-N 3.08Å
348	C	51.3	Low	55.7	Low	50 Å²	50	85 Å²	85	34%	0.338	47%	0.472	S	S	.	.	T	Hydrogen-bonded Turn	trans	-79.9	-28.5	-179.2	-107.5	0	0	0	0	114.3	D346 C420	D346-C348 PolarHBondContact O-N 3.17Å; D346-C348 VanDerWaalsContact O-N 3.17Å; C348-C420 WeakPolarHBondContact CA-SG 3.45Å; C348-C420 HydrophobicContact CB-CB 4.43Å; C348-C420 WeakPolarHBondContact CB-SG 3.06Å; C348-C420 WeakPolarHBondContact SG-CA 3.48Å; C348-C420 WeakPolarHBondContact SG-CB 3.38Å; C348-C420 CovalentContact SG-SG 2.02Å; C348-C420 PolarHBondContact SG-SG 3.44Å
349	S	43.8	Very low	53.3	Low	76 Å²	76	88.5 Å²	88.5	53%	0.531	50%	0.501	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.2	-27.5	178.9	76.8	0	0	0	0	111.9	D346 S351	D346-S349 PolarHBondContact O-N 3.4Å; D346-S349 PolarHBondContact O-OG 3.11Å; D346-S349 VanDerWaalsContact O-OG 3.09Å; D346-S349 PolarHBondContact OD1-OG 3.08Å; S349-S351 VanDerWaalsContact C-N 3.3Å; S349-S351 PolarHBondContact O-N 3.4Å
350	I	45.7	Very low	50.7	Low	112 Å²	112	97.3 Å²	97.3	57%	0.574	54%	0.539	S	S	*	.	G	3₁₀ helix	trans	-72.5	-21.6	-179	-61.8	169.3	0	0	0	112.3	S352 R353	I350-S352 PolarHBondContact O-N 3.34Å; I350-S352 VanDerWaalsContact O-N 3.08Å; I350-R353 PolarHBondContact O-N 3.34Å
351	S	39.7	Very low	48.7	Very low	102 Å²	102	98.9 Å²	98.9	71%	0.713	55%	0.551	S	S	*	*	G	3₁₀ helix	trans	-63.2	-16.4	-179.8	-167.5	0	0	0	0	114.2	S349 R353	S349-S351 VanDerWaalsContact C-N 3.3Å; S349-S351 PolarHBondContact O-N 3.4Å; S351-R353 VanDerWaalsContact C-N 3.29Å; S351-R353 PolarHBondContact O-N 2.86Å
352	S	39.1	Very low	46.7	Very low	120 Å²	120	102.9 Å²	102.9	84%	0.839	58%	0.58	S	S	*	*	G	3₁₀ helix	trans	-76.7	-7.3	170.1	-78.5	0	0	0	0	114.4	I350	I350-S352 PolarHBondContact O-N 3.34Å; I350-S352 VanDerWaalsContact O-N 3.08Å
353	R	38.5	Very low	45.2	Very low	222 Å²	222	104.5 Å²	104.5	84%	0.838	59%	0.589	S	S	*	*	S	Bend	trans	-120.3	85.7	170.7	-78.7	-173.3	-144.8	-179.1	8.5	111.5	I350 S351	I350-R353 PolarHBondContact O-N 3.34Å; S351-R353 VanDerWaalsContact C-N 3.29Å; S351-R353 PolarHBondContact O-N 2.86Å
354	K	35.6	Very low	44.3	Very low	201 Å²	201	106.5 Å²	106.5	87%	0.874	61%	0.61	S	S	*	*			trans	39.4	126.3	151.2	-80.3	-178.1	176.5	175	0	119.3
355	K	35.1	Very low	44.4	Very low	192 Å²	192	108.3 Å²	108.3	84%	0.835	62%	0.62	S	S	*	*			trans	90.5	120	154.8	-79.3	-177.4	172.2	-179.3	0	116.5	V357	K355-V357 VanDerWaalsContact C-N 3.33Å; K355-V357 PolarHBondContact O-N 3.1Å
356	A	36.8	Very low	45.2	Very low	110 Å²	110	111.4 Å²	111.4	91%	0.909	62%	0.624	S	S	*	*			trans	-40.4	95.8	153.5	0	0	0	0	0	110.6
357	V	37.2	Very low	46.5	Very low	121 Å²	121	112 Å²	112	73%	0.733	62%	0.62	S	S	*	*			trans	-113.8	125.8	154.9	177.2	0	0	0	0	102.6	K355 A359	K355-V357 VanDerWaalsContact C-N 3.33Å; K355-V357 PolarHBondContact O-N 3.1Å; V357-A359 PolarHBondContact O-N 3.39Å
358	E	37.9	Very low	48.1	Very low	176 Å²	176	109 Å²	109	82%	0.822	60%	0.601	S	S	*	*			trans	-42	113	167.2	-77.1	171.9	141.5	0	0	107.9	K360	E358-K360 PolarHBondContact O-N 3.21Å
359	A	39.3	Very low	49.7	Very low	74 Å²	74	109 Å²	109	61%	0.612	60%	0.601	S	S	*	*			trans	-67.3	81.8	172.9	0	0	0	0	0	106.8	V357 C361	V357-A359 PolarHBondContact O-N 3.39Å; A359-C361 PolarHBondContact O-N 3.4Å
360	K	34.2	Very low	51.6	Low	184 Å²	184	112 Å²	112	80%	0.8	61%	0.607	S	S	*	*			trans	-62.7	89.5	149.3	-81.7	-175.9	177.2	178.4	0	104.8	E358 S362	E358-K360 PolarHBondContact O-N 3.21Å; K360-S362 PolarHBondContact O-N 2.84Å
361	C	41.1	Very low	53.6	Low	39 Å²	39	112.8 Å²	112.8	26%	0.264	61%	0.608	S	S	.	*			trans	-62.9	79	157.9	-88.7	0	0	0	0	106.6	A359 L363	A359-C361 PolarHBondContact O-N 3.4Å; C361-L363 PolarHBondContact O-N 3.07Å; C361-L363 VanDerWaalsContact O-N 3.09Å
362	S	41.8	Very low	55.9	Low	103 Å²	103	108.5 Å²	108.5	72%	0.72	58%	0.577	S	S	*	*			trans	-64.1	104.8	145.1	54.4	0	0	0	0	103.7	K360 A364	K360-S362 PolarHBondContact O-N 2.84Å; S362-A364 PolarHBondContact O-N 3.49Å
363	L	51.2	Low	58.4	Low	42 Å²	42	103.1 Å²	103.1	22%	0.22	54%	0.539	C	S	.	.			trans	-50.8	97.7	172.3	-163.1	76.8	0	0	0	106.2	C361 C365 E484	C361-L363 PolarHBondContact O-N 3.07Å; C361-L363 VanDerWaalsContact O-N 3.09Å; L363-C365 PolarHBondContact O-N 3.3Å; L363-E484 HydrophobicContact CB-CG 4.31Å
364	A	56.8	Low	60.9	Low	67 Å²	67	96.7 Å²	96.7	55%	0.554	52%	0.519	S	S	*	.			trans	-62.5	128.1	173.7	0	0	0	0	0	104.7	S362 E366	S362-A364 PolarHBondContact O-N 3.49Å; A364-E366 PolarHBondContact O-N 3.37Å
365	C	67.6	Low	63.5	Low	61 Å²	61	88 Å²	88	41%	0.412	48%	0.482	S	S	.	.			trans	-62.7	103	175.1	151.7	0	0	0	0	108	C113 L363	C113-C365 WeakPolarHBondContact CA-SG 3.45Å; C113-C365 HydrophobicContact CB-CB 4.15Å; C113-C365 WeakPolarHBondContact CB-SG 3.49Å; C113-C365 WeakPolarHBondContact SG-CA 3.43Å; C113-C365 WeakPolarHBondContact SG-CB 3.28Å; C113-C365 CovalentContact SG-SG 2.03Å; C113-C365 PolarHBondContact SG-SG 2.83Å; L363-C365 PolarHBondContact O-N 3.3Å
366	E	72.7	Confident	66.2	Low	102 Å²	102	78.8 Å²	78.8	48%	0.477	44%	0.442	S	S	.	.			trans	-119.1	132.5	172.4	-69.7	-168.2	168.2	0	0	108.9	Q343 A364	Q343-E366 PolarHBondContact NE2-O 3.37Å; A364-E366 PolarHBondContact O-N 3.37Å
367	Y	81.3	Confident	69	Low	117 Å²	117	75.2 Å²	75.2	46%	0.459	41%	0.407	S	S	.	.	P	Polyproline II helix	trans	-76.4	148.2	175	-66.8	-72	0	0	0	110.1	C113 S369	C113-Y367 HydrophobicContact CB-CD1 3.99Å; C113-Y367 HydrophobicContact CB-CE1 3.35Å; C113-Y367 HydrophobicContact CB-CE2 4.4Å; Y367-S369 PolarHBondContact O-N 3.07Å
368	L	83.5	Confident	71.7	Confident	17 Å²	17	76.7 Å²	76.7	9%	0.089	40%	0.4	C	S	.	.	P	Polyproline II helix	trans	-61.4	128.8	173.1	-88.8	76	0	0	0	109.8	P109 T339 Q343 D372 Y373	P109-L368 HydrophobicContact CB-CD1 3.96Å; P109-L368 HydrophobicContact CG-CD1 3.71Å; T339-L368 HydrophobicContact CG2-CD2 4.26Å; Q343-L368 HydrophobicContact CG-CD1 3.88Å; Q343-L368 HydrophobicContact CG-CG 4.49Å; L368-D372 HydrophobicContact CB-CB 4.23Å; L368-D372 HydrophobicContact CD2-CB 4.29Å; L368-D372 HydrophobicContact CG-CB 4.07Å; L368-Y373 HydrophobicContact CB-CD2 4.31Å; L368-Y373 HydrophobicContact CB-CE1 4.25Å; L368-Y373 HydrophobicContact CB-CE2 3.7Å; L368-Y373 HydrophobicContact CD2-CD1 4.23Å; L368-Y373 HydrophobicContact CD2-CE1 3.88Å
369	S	84.2	Confident	74.4	Confident	50 Å²	50	68.3 Å²	68.3	35%	0.35	36%	0.361	S	S	.	.	P	Polyproline II helix	trans	-82.8	167.1	174.9	68.7	0	0	0	0	111.6	Y367 E371 D372 Y373	Y367-S369 PolarHBondContact O-N 3.07Å; S369-E371 PolarHBondContact O-N 3.49Å; S369-D372 WeakPolarHBondContact CB-OD2 3.31Å; S369-D372 PolarHBondContact N-OD2 3.45Å; S369-D372 PolarHBondContact O-N 3.48Å; S369-D372 PolarHBondContact OG-N 2.56Å; S369-D372 PolarHBondContact OG-OD2 3.06Å; S369-Y373 WeakPolarHBondContact O-CD2 3.33Å; S369-Y373 PolarHBondContact O-N 2.91Å; S369-Y373 VanDerWaalsContact O-N 3.16Å
370	E	85.3	Confident	77	Confident	139 Å²	139	64.8 Å²	64.8	65%	0.65	33%	0.332	S	S	*	.	H	α-helix	trans	-56.5	-35.4	173.8	-67.4	-175.4	-179.3	0	0	112	Y373 M374	E370-Y373 PolarHBondContact O-N 2.92Å; E370-M374 VanDerWaalsContact O-CG 3.31Å; E370-M374 WeakPolarHBondContact O-CG 3.15Å; E370-M374 PolarHBondContact O-N 2.88Å; E370-M374 VanDerWaalsContact O-N 3.07Å
371	E	86.1	Confident	79.9	Confident	129 Å²	129	58.7 Å²	58.7	60%	0.603	31%	0.308	S	S	*	.	H	α-helix	trans	-65.2	-39	176.3	-61.1	-173.1	178.9	0	0	111.6	S369 M374 D375 R423	S369-E371 PolarHBondContact O-N 3.49Å; E371-M374 PolarHBondContact O-N 3.22Å; E371-D375 PolarHBondContact O-N 3.39Å; E371-R423 PolarHBondContact O-NH2 3.37Å; E371-R423 VanDerWaalsContact O-NH2 3.08Å
372	D	89.6	Confident	82.4	Confident	12 Å²	12	56.9 Å²	56.9	6%	0.064	30%	0.295	C	S	.	.	H	α-helix	trans	-67.6	-37.8	179.5	-55.2	-40.3	0	0	0	111.5	F342 L368 S369 D375 L376 R423	F342-D372 HydrophobicContact CB-CB 4.32Å; L368-D372 HydrophobicContact CB-CB 4.23Å; L368-D372 HydrophobicContact CD2-CB 4.29Å; L368-D372 HydrophobicContact CG-CB 4.07Å; S369-D372 WeakPolarHBondContact CB-OD2 3.31Å; S369-D372 PolarHBondContact N-OD2 3.45Å; S369-D372 PolarHBondContact O-N 3.48Å; S369-D372 PolarHBondContact OG-N 2.56Å; S369-D372 PolarHBondContact OG-OD2 3.06Å; D372-D375 PolarHBondContact O-N 3.1Å; D372-L376 WeakPolarHBondContact O-CB 3.39Å; D372-L376 PolarHBondContact O-N 2.89Å; D372-R423 VanDerWaalsContact CA-NH2 3.29Å; D372-R423 VanDerWaalsContact N-NH2 3.12Å; D372-R423 IonicContact OD1-CZ 3.05Å; D372-R423 VanDerWaalsContact OD1-CZ 3.26Å; D372-R423 IonicContact OD1-NH1 3.98Å; D372-R423 PolarHBondContact OD1-NH1 3.37Å; D372-R423 IonicContact OD1-NH2 2.66Å; D372-R423 PolarHBondContact OD1-NH2 3.36Å
373	Y	90.3	Very high	84.8	Confident	7 Å²	7	52 Å²	52	3%	0.027	26%	0.261	C	S	.	.	H	α-helix	trans	-67	-36.9	173.3	-70.7	-66.3	0	0	0	112.5	I106 A228 V229 M232 L368 S369 E370 L376 L377	I106-Y373 HydrophobicContact CG2-CE1 3.93Å; A228-Y373 HydrophobicContact CB-CD1 4.1Å; A228-Y373 HydrophobicContact CB-CE1 3.89Å; V229-Y373 HydrophobicContact CG2-CG 4.46Å; M232-Y373 HydrophobicContact CB-CE2 4.13Å; M232-Y373 WeakPolarHBondContact CB-OH 3.21Å; M232-Y373 WeakPolarHBondContact CE-OH 3.21Å; M232-Y373 HydrophobicContact CG-CE1 4.3Å; M232-Y373 WeakPolarHBondContact CG-OH 3.38Å; L368-Y373 HydrophobicContact CB-CD2 4.31Å; L368-Y373 HydrophobicContact CB-CE1 4.25Å; L368-Y373 HydrophobicContact CB-CE2 3.7Å; L368-Y373 HydrophobicContact CD2-CD1 4.23Å; L368-Y373 HydrophobicContact CD2-CE1 3.88Å; S369-Y373 WeakPolarHBondContact O-CD2 3.33Å; S369-Y373 PolarHBondContact O-N 2.91Å; S369-Y373 VanDerWaalsContact O-N 3.16Å; E370-Y373 PolarHBondContact O-N 2.92Å; Y373-L376 PolarHBondContact O-N 3.48Å; Y373-L377 WeakPolarHBondContact O-CB 3.25Å; Y373-L377 PolarHBondContact O-N 2.85Å
374	M	91.1	Very high	86.8	Confident	88 Å²	88	53.2 Å²	53.2	43%	0.433	27%	0.265	S	S	.	.	H	α-helix	trans	-67	-39.3	175	-69.1	-64.9	174.5	0	0	111.9	V229 E370 E371 L377 W378	V229-M374 HydrophobicContact CG1-CE 3.95Å; E370-M374 VanDerWaalsContact O-CG 3.31Å; E370-M374 WeakPolarHBondContact O-CG 3.15Å; E370-M374 PolarHBondContact O-N 2.88Å; E370-M374 VanDerWaalsContact O-N 3.07Å; E371-M374 PolarHBondContact O-N 3.22Å; M374-L377 WeakPolarHBondContact O-CB 3.34Å; M374-L377 PolarHBondContact O-N 3.33Å; M374-L377 HydrophobicContact SD-CD2 4.5Å; M374-W378 PolarHBondContact O-N 3.31Å
375	D	91.2	Very high	88.4	Confident	17 Å²	17	52.5 Å²	52.5	9%	0.091	25%	0.254	C	S	.	.	H	α-helix	trans	-69.1	-36.5	174.1	-77.5	-51.5	0	0	0	112.5	F342 E371 D372 L377 W378 T379 R423 T427	F342-D375 HydrophobicContact CD1-CB 4.42Å; F342-D375 HydrophobicContact CD2-CB 4.32Å; F342-D375 HydrophobicContact CE1-CB 3.87Å; F342-D375 HydrophobicContact CE2-CB 3.72Å; F342-D375 HydrophobicContact CZ-CB 3.5Å; F342-D375 VanDerWaalsContact CZ-CB 3.5Å; E371-D375 PolarHBondContact O-N 3.39Å; D372-D375 PolarHBondContact O-N 3.1Å; D375-L377 VanDerWaalsContact C-N 3.27Å; D375-L377 PolarHBondContact O-N 3.12Å; D375-W378 PolarHBondContact O-N 3.15Å; D375-T379 WeakPolarHBondContact O-CG2 3.24Å; D375-T379 PolarHBondContact O-N 3.38Å; D375-T379 PolarHBondContact O-OG1 2.93Å; D375-T379 VanDerWaalsContact O-OG1 3.13Å; D375-R423 IonicContact OD2-CZ 3.59Å; D375-R423 IonicContact OD2-NE 2.71Å; D375-R423 PolarHBondContact OD2-NE 2.62Å; D375-R423 IonicContact OD2-NH2 2.81Å; D375-R423 PolarHBondContact OD2-NH2 3.24Å; D375-T427 HydrophobicContact CB-CG2 4.19Å; D375-T427 VanDerWaalsContact CG-OG1 3.23Å; D375-T427 WeakPolarHBondContact OD1-CB 3.24Å; D375-T427 VanDerWaalsContact OD1-CG2 3.27Å; D375-T427 WeakPolarHBondContact OD1-CG2 3.2Å; D375-T427 PolarHBondContact OD1-OG1 3.16Å
376	L	92.1	Very high	89.5	Confident	0 Å²	0	49.8 Å²	49.8	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-61.7	-38.1	170.2	-171.3	64.9	0	0	0	111.1	I106 V225 T338 T339 D372 Y373 T379 T380	I106-L376 HydrophobicContact CD1-CD2 3.98Å; I106-L376 HydrophobicContact CG1-CD2 3.88Å; V225-L376 HydrophobicContact CG1-CB 4.11Å; V225-L376 HydrophobicContact CG1-CD2 4.06Å; V225-L376 HydrophobicContact CG1-CG 3.98Å; V225-L376 HydrophobicContact CG2-CD2 3.8Å; V225-L376 HydrophobicContact CG2-CG 3.81Å; T338-L376 HydrophobicContact CG2-CD1 3.82Å; T339-L376 HydrophobicContact CG2-CD1 3.96Å; T339-L376 HydrophobicContact CG2-CD2 4.01Å; D372-L376 WeakPolarHBondContact O-CB 3.39Å; D372-L376 PolarHBondContact O-N 2.89Å; Y373-L376 PolarHBondContact O-N 3.48Å; L376-T379 WeakPolarHBondContact CA-OG1 3.45Å; L376-T379 PolarHBondContact O-OG1 3.42Å; L376-T380 WeakPolarHBondContact O-CB 3.45Å; L376-T380 VanDerWaalsContact O-CG2 3.25Å; L376-T380 WeakPolarHBondContact O-CG2 3.43Å; L376-T380 PolarHBondContact O-N 3.19Å; L376-T380 PolarHBondContact O-OG1 2.95Å
377	L	94.4	Very high	90.2	Very high	34 Å²	34	45.5 Å²	45.5	18%	0.178	22%	0.218	C	C	.	.	H	α-helix	trans	-65.4	-45.5	175.8	-178	62.1	0	0	0	111.3	V222 V225 V226 Y373 M374 D375 T380 L381	V222-L377 HydrophobicContact CG1-CD1 3.97Å; V225-L377 HydrophobicContact CG1-CB 3.91Å; V225-L377 HydrophobicContact CG1-CD1 4.31Å; V226-L377 HydrophobicContact CG2-CD1 3.68Å; Y373-L377 WeakPolarHBondContact O-CB 3.25Å; Y373-L377 PolarHBondContact O-N 2.85Å; M374-L377 WeakPolarHBondContact O-CB 3.34Å; M374-L377 PolarHBondContact O-N 3.33Å; M374-L377 HydrophobicContact SD-CD2 4.5Å; D375-L377 VanDerWaalsContact C-N 3.27Å; D375-L377 PolarHBondContact O-N 3.12Å; L377-T380 WeakPolarHBondContact CA-OG1 3.31Å; L377-T380 PolarHBondContact O-N 2.88Å; L377-T380 PolarHBondContact O-OG1 3.48Å; L377-L381 HydrophobicContact CD1-CD1 4.41Å; L377-L381 HydrophobicContact CD1-CG 4.4Å; L377-L381 HydrophobicContact CG-CD1 4.14Å; L377-L381 WeakPolarHBondContact O-CB 3.48Å; L377-L381 VanDerWaalsContact O-CG 3.28Å; L377-L381 WeakPolarHBondContact O-CG 3.25Å; L377-L381 PolarHBondContact O-N 2.95Å
378	W	93.9	Very high	90.5	Very high	152 Å²	152	45.8 Å²	45.8	58%	0.576	23%	0.226	S	C	*	.	H	α-helix	trans	-60.3	-48.6	176.2	-78	118.5	0	0	0	112	M374 D375 T380 L381 T427 F431	M374-W378 PolarHBondContact O-N 3.31Å; D375-W378 PolarHBondContact O-N 3.15Å; W378-T380 VanDerWaalsContact C-N 3.33Å; W378-T380 PolarHBondContact O-N 3.45Å; W378-L381 HydrophobicContact CE3-CD1 4.19Å; W378-L381 HydrophobicContact CZ3-CD1 4.37Å; W378-L381 PolarHBondContact O-N 3.49Å; W378-T427 HydrophobicContact CB-CG2 3.93Å; W378-F431 WeakPolarHBondContact O-CD2 3.37Å; W378-F431 WeakPolarHBondContact O-CE2 3.39Å
379	T	94.3	Very high	90.9	Very high	0 Å²	0	48 Å²	48	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-62.5	-39.6	179.9	55.7	0	0	0	0	111.9	T338 F342 D375 L376 S382 T427 L430 R434	T338-T379 HydrophobicContact CG2-CG2 4.48Å; F342-T379 HydrophobicContact CZ-CG2 4.36Å; D375-T379 WeakPolarHBondContact O-CG2 3.24Å; D375-T379 PolarHBondContact O-N 3.38Å; D375-T379 PolarHBondContact O-OG1 2.93Å; D375-T379 VanDerWaalsContact O-OG1 3.13Å; L376-T379 WeakPolarHBondContact CA-OG1 3.45Å; L376-T379 PolarHBondContact O-OG1 3.42Å; T379-S382 WeakPolarHBondContact O-CB 3.34Å; T379-S382 PolarHBondContact O-N 3.27Å; T379-S382 PolarHBondContact O-OG 3.38Å; T379-T427 HydrophobicContact CG2-CG2 4.05Å; T379-L430 HydrophobicContact CG2-CB 3.65Å; T379-R434 WeakPolarHBondContact O-CD 3.18Å
380	T	93.9	Very high	91	Very high	0 Å²	0	45.8 Å²	45.8	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-71	-35.2	178.5	50.1	0	0	0	0	113.8	M102 V225 L376 L377 W378 S382 E383	M102-T380 HydrophobicContact CE-CG2 3.3Å; M102-T380 HydrophobicContact SD-CG2 4.33Å; V225-T380 HydrophobicContact CG2-CG2 3.93Å; L376-T380 WeakPolarHBondContact O-CB 3.45Å; L376-T380 VanDerWaalsContact O-CG2 3.25Å; L376-T380 WeakPolarHBondContact O-CG2 3.43Å; L376-T380 PolarHBondContact O-N 3.19Å; L376-T380 PolarHBondContact O-OG1 2.95Å; L377-T380 WeakPolarHBondContact CA-OG1 3.31Å; L377-T380 PolarHBondContact O-N 2.88Å; L377-T380 PolarHBondContact O-OG1 3.48Å; W378-T380 VanDerWaalsContact C-N 3.33Å; W378-T380 PolarHBondContact O-N 3.45Å; T380-S382 PolarHBondContact O-N 3.27Å; T380-E383 PolarHBondContact O-N 3.35Å; T380-E383 VanDerWaalsContact O-N 3.13Å
381	L	95	Very high	91	Very high	57 Å²	57	41.7 Å²	41.7	30%	0.298	21%	0.207	S	C	.	.	H	α-helix	trans	-59.2	-18.5	172.6	-78.3	169.2	0	0	0	113.1	V222 L377 W378 E383 F384 P385	V222-L381 HydrophobicContact CG1-CD2 4.03Å; V222-L381 HydrophobicContact CG2-CD2 4.08Å; V222-L381 HydrophobicContact CG2-CG 4.33Å; L377-L381 HydrophobicContact CD1-CD1 4.41Å; L377-L381 HydrophobicContact CD1-CG 4.4Å; L377-L381 HydrophobicContact CG-CD1 4.14Å; L377-L381 WeakPolarHBondContact O-CB 3.48Å; L377-L381 VanDerWaalsContact O-CG 3.28Å; L377-L381 WeakPolarHBondContact O-CG 3.25Å; L377-L381 PolarHBondContact O-N 2.95Å; W378-L381 HydrophobicContact CE3-CD1 4.19Å; W378-L381 HydrophobicContact CZ3-CD1 4.37Å; W378-L381 PolarHBondContact O-N 3.49Å; L381-E383 PolarHBondContact O-N 3.32Å; L381-F384 HydrophobicContact CD2-CD2 4.32Å; L381-F384 HydrophobicContact CD2-CE2 4.36Å; L381-F384 PolarHBondContact O-N 3.41Å; L381-P385 WeakPolarHBondContact O-CD 3.1Å
382	S	94.5	Very high	91	Very high	0 Å²	0	43.1 Å²	43.1	0%	0	21%	0.207	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64.8	-20	176.8	96.9	0	0	0	0	114	T379 T380 F384 P385 G386 F431 R434 A435	T379-S382 WeakPolarHBondContact O-CB 3.34Å; T379-S382 PolarHBondContact O-N 3.27Å; T379-S382 PolarHBondContact O-OG 3.38Å; T380-S382 PolarHBondContact O-N 3.27Å; S382-F384 VanDerWaalsContact C-N 3.34Å; S382-F384 PolarHBondContact O-N 3.34Å; S382-P385 VanDerWaalsContact O-CD 3.28Å; S382-P385 WeakPolarHBondContact O-CD 3.35Å; S382-P385 WeakPolarHBondContact O-CG 3.43Å; S382-G386 WeakPolarHBondContact O-CA 3.26Å; S382-G386 PolarHBondContact O-N 2.92Å; S382-F431 VanDerWaalsContact CA-CE2 3.48Å; S382-F431 VanDerWaalsContact CB-CG 3.49Å; S382-F431 WeakPolarHBondContact CB-O 3.43Å; S382-F431 PolarHBondContact OG-O 3.24Å; S382-R434 WeakPolarHBondContact OG-CB 3.41Å; S382-A435 WeakPolarHBondContact O-CB 2.84Å; S382-A435 PolarHBondContact OG-N 2.69Å; S382-A435 VanDerWaalsContact OG-N 3.12Å
383	E	92.5	Very high	91	Very high	1 Å²	1	43.5 Å²	43.5	1%	0.005	21%	0.209	C	C	.	.	H	α-helix	trans	-61.2	-44.1	178.5	-68.2	-175.3	177.2	0	0	110.5	A218 T221 Y331 T380 L381 G386 V387 R434	A218-E383 WeakPolarHBondContact CA-OE2 3.39Å; A218-E383 HydrophobicContact CB-CB 3.86Å; T221-E383 PolarHBondContact OG1-OE2 2.83Å; Y331-E383 PolarHBondContact OH-OE1 3.42Å; T380-E383 PolarHBondContact O-N 3.35Å; T380-E383 VanDerWaalsContact O-N 3.13Å; L381-E383 PolarHBondContact O-N 3.32Å; E383-G386 PolarHBondContact O-N 3.14Å; E383-V387 VanDerWaalsContact O-CG2 3.26Å; E383-V387 WeakPolarHBondContact O-CG2 3.17Å; E383-V387 PolarHBondContact O-N 2.97Å; E383-R434 HydrophobicContact CG-CG 4.38Å; E383-R434 IonicContact OE1-CZ 3.12Å; E383-R434 VanDerWaalsContact OE1-CZ 3.24Å; E383-R434 IonicContact OE1-NE 2.71Å; E383-R434 PolarHBondContact OE1-NE 3.39Å; E383-R434 IonicContact OE1-NH2 2.72Å; E383-R434 PolarHBondContact OE1-NH2 2.96Å
384	F	91.9	Very high	90.9	Very high	67 Å²	67	43.7 Å²	43.7	29%	0.294	21%	0.21	S	C	.	.	H	α-helix	trans	-57.2	-58.5	178.8	-66.1	-77.4	0	0	0	114.5	V215 A218 I219 V222 L381 S382 G386 V387 L388	V215-F384 HydrophobicContact CG1-CD1 4.47Å; V215-F384 HydrophobicContact CG1-CE1 4.02Å; A218-F384 HydrophobicContact CB-CD1 4.18Å; A218-F384 HydrophobicContact CB-CD2 4.48Å; A218-F384 HydrophobicContact CB-CE1 3.88Å; A218-F384 HydrophobicContact CB-CE2 4.21Å; A218-F384 HydrophobicContact CB-CG 4.46Å; A218-F384 HydrophobicContact CB-CZ 3.9Å; I219-F384 HydrophobicContact CG1-CE1 3.99Å; I219-F384 HydrophobicContact CG1-CZ 3.83Å; V222-F384 HydrophobicContact CB-CE2 4.4Å; V222-F384 HydrophobicContact CG2-CE2 3.85Å; L381-F384 HydrophobicContact CD2-CD2 4.32Å; L381-F384 HydrophobicContact CD2-CE2 4.36Å; L381-F384 PolarHBondContact O-N 3.41Å; S382-F384 VanDerWaalsContact C-N 3.34Å; S382-F384 PolarHBondContact O-N 3.34Å; F384-G386 VanDerWaalsContact C-N 3.27Å; F384-G386 PolarHBondContact O-N 3.13Å; F384-V387 PolarHBondContact O-N 2.84Å; F384-L388 PolarHBondContact O-N 3.23Å
385	P	91.8	Very high	90.5	Very high	52 Å²	52	44.3 Å²	44.3	34%	0.338	22%	0.216	S	C	.	.	H	α-helix	trans	-65.5	-32.7	176.1	27	-33.3	0	0	0	111.5	L381 S382 V387 L388 V389 F431	L381-P385 WeakPolarHBondContact O-CD 3.1Å; S382-P385 VanDerWaalsContact O-CD 3.28Å; S382-P385 WeakPolarHBondContact O-CD 3.35Å; S382-P385 WeakPolarHBondContact O-CG 3.43Å; P385-V387 PolarHBondContact O-N 3.44Å; P385-L388 PolarHBondContact O-N 2.88Å; P385-V389 WeakPolarHBondContact O-CB 3.03Å; P385-V389 VanDerWaalsContact O-CG2 3.24Å; P385-V389 WeakPolarHBondContact O-CG2 3.33Å; P385-V389 PolarHBondContact O-N 2.81Å; P385-F431 HydrophobicContact CG-CE1 4.45Å; P385-F431 HydrophobicContact CG-CZ 3.91Å
386	G	90.4	Very high	90.3	Very high	4 Å²	4	51.7 Å²	51.7	4%	0.041	24%	0.242	C	C	.	.	H	α-helix	trans	-58.3	-45.7	176.1	0	0	0	0	0	112.9	S382 E383 F384 T390	S382-G386 WeakPolarHBondContact O-CA 3.26Å; S382-G386 PolarHBondContact O-N 2.92Å; E383-G386 PolarHBondContact O-N 3.14Å; F384-G386 VanDerWaalsContact C-N 3.27Å; F384-G386 PolarHBondContact O-N 3.13Å; G386-T390 VanDerWaalsContact O-CB 3.26Å; G386-T390 WeakPolarHBondContact O-CB 3.37Å; G386-T390 PolarHBondContact O-N 3.05Å; G386-T390 PolarHBondContact O-OG1 2.76Å
387	V	86.4	Confident	90.1	Very high	13 Å²	13	55.7 Å²	55.7	8%	0.079	26%	0.263	C	S	.	.	H	α-helix	trans	-60.5	-49.8	174.9	172.9	0	0	0	0	110.9	E383 F384 P385 V389 T390 L391	E383-V387 VanDerWaalsContact O-CG2 3.26Å; E383-V387 WeakPolarHBondContact O-CG2 3.17Å; E383-V387 PolarHBondContact O-N 2.97Å; F384-V387 PolarHBondContact O-N 2.84Å; P385-V387 PolarHBondContact O-N 3.44Å; V387-V389 PolarHBondContact O-N 2.03Å; V387-T390 PolarHBondContact O-N 3.43Å; V387-L391 HydrophobicContact CG1-CD1 3.88Å; V387-L391 HydrophobicContact CG1-CG 4.36Å; V387-L391 WeakPolarHBondContact O-CB 3.27Å; V387-L391 VanDerWaalsContact O-CG 3.27Å; V387-L391 WeakPolarHBondContact O-CG 3.42Å; V387-L391 PolarHBondContact O-N 2.84Å
388	L	89.1	Confident	89.7	Confident	122 Å²	122	54 Å²	54	64%	0.639	25%	0.254	S	S	*	.	H	α-helix	trans	-62.8	-44.9	-178.4	-65.4	176.4	0	0	0	112.4	F384 P385 L391 W392	F384-L388 PolarHBondContact O-N 3.23Å; P385-L388 PolarHBondContact O-N 2.88Å; L388-L391 PolarHBondContact O-N 3.48Å; L388-W392 PolarHBondContact O-N 3.42Å
389	V	90.8	Very high	89.5	Confident	65 Å²	65	48.4 Å²	48.4	39%	0.394	23%	0.233	S	C	.	.	H	α-helix	trans	-63.2	-45.2	177.2	169.4	0	0	0	0	110.2	P385 V387 L391 W392 I393	P385-V389 WeakPolarHBondContact O-CB 3.03Å; P385-V389 VanDerWaalsContact O-CG2 3.24Å; P385-V389 WeakPolarHBondContact O-CG2 3.33Å; P385-V389 PolarHBondContact O-N 2.81Å; V387-V389 PolarHBondContact O-N 2.03Å; V389-L391 PolarHBondContact O-N 3.14Å; V389-W392 PolarHBondContact O-N 3.24Å; V389-I393 HydrophobicContact CG1-CD1 3.59Å; V389-I393 HydrophobicContact CG1-CG1 4.29Å; V389-I393 WeakPolarHBondContact O-CG1 3.37Å; V389-I393 PolarHBondContact O-N 3.27Å
390	T	86.4	Confident	89.3	Confident	3 Å²	3	50.7 Å²	50.7	2%	0.018	24%	0.243	C	C	.	.	H	α-helix	trans	-64.6	-42.6	-179.9	-55.8	0	0	0	0	111.6	G386 V387 W392 I393 I394 T402 G439	G386-T390 VanDerWaalsContact O-CB 3.26Å; G386-T390 WeakPolarHBondContact O-CB 3.37Å; G386-T390 PolarHBondContact O-N 3.05Å; G386-T390 PolarHBondContact O-OG1 2.76Å; V387-T390 PolarHBondContact O-N 3.43Å; T390-W392 VanDerWaalsContact C-N 3.3Å; T390-W392 PolarHBondContact O-N 2.89Å; T390-I393 PolarHBondContact O-N 2.83Å; T390-I394 WeakPolarHBondContact O-CB 3.4Å; T390-I394 PolarHBondContact O-N 3.08Å; T390-T402 HydrophobicContact CG2-CG2 3.91Å; T390-G439 WeakPolarHBondContact CG2-O 3.17Å; T390-G439 VanDerWaalsContact OG1-CA 3.25Å; T390-G439 WeakPolarHBondContact OG1-CA 3.24Å
391	L	84.8	Confident	89.3	Confident	52 Å²	52	57.1 Å²	57.1	27%	0.272	27%	0.271	S	S	.	.	H	α-helix	trans	-60.3	-40.2	174.5	-73.7	174.1	0	0	0	111.9	L211 V387 L388 V389 I394	L211-L391 HydrophobicContact CD1-CD2 3.68Å; L211-L391 HydrophobicContact CD2-CD2 4.11Å; L211-L391 HydrophobicContact CG-CD2 4.44Å; V387-L391 HydrophobicContact CG1-CD1 3.88Å; V387-L391 HydrophobicContact CG1-CG 4.36Å; V387-L391 WeakPolarHBondContact O-CB 3.27Å; V387-L391 VanDerWaalsContact O-CG 3.27Å; V387-L391 WeakPolarHBondContact O-CG 3.42Å; V387-L391 PolarHBondContact O-N 2.84Å; L388-L391 PolarHBondContact O-N 3.48Å; V389-L391 PolarHBondContact O-N 3.14Å; L391-I394 WeakPolarHBondContact O-CG2 3.27Å
392	W	87.7	Confident	89.2	Confident	160 Å²	160	54.4 Å²	54.4	61%	0.606	26%	0.257	S	S	*	.	H	α-helix	trans	-66.7	-40.2	175.2	-177.7	82	0	0	0	112.3	L388 V389 T390 R396	L388-W392 PolarHBondContact O-N 3.42Å; V389-W392 PolarHBondContact O-N 3.24Å; T390-W392 VanDerWaalsContact C-N 3.3Å; T390-W392 PolarHBondContact O-N 2.89Å; W392-R396 HydrophobicContact CZ2-CG 4.44Å; W392-R396 WeakPolarHBondContact O-CG 3.34Å; W392-R396 PolarHBondContact O-N 3.49Å
393	I	89.6	Confident	89.2	Confident	19 Å²	19	54.4 Å²	54.4	10%	0.097	26%	0.257	C	S	.	.	H	α-helix	trans	-67.9	-40	178.5	-66.4	171.2	0	0	0	111.3	V389 T390 D395 R396 L397 T402 L405 F436	V389-I393 HydrophobicContact CG1-CD1 3.59Å; V389-I393 HydrophobicContact CG1-CG1 4.29Å; V389-I393 WeakPolarHBondContact O-CG1 3.37Å; V389-I393 PolarHBondContact O-N 3.27Å; T390-I393 PolarHBondContact O-N 2.83Å; I393-D395 VanDerWaalsContact C-N 3.26Å; I393-D395 PolarHBondContact O-N 3.43Å; I393-R396 PolarHBondContact O-N 2.8Å; I393-L397 HydrophobicContact CG2-CB 4.27Å; I393-L397 HydrophobicContact CG2-CD1 3.63Å; I393-L397 HydrophobicContact CG2-CG 4.04Å; I393-L397 PolarHBondContact O-N 3.43Å; I393-T402 HydrophobicContact CB-CG2 4.33Å; I393-T402 HydrophobicContact CG2-CG2 3.87Å; I393-L405 HydrophobicContact CD1-CD2 4.32Å; I393-L405 HydrophobicContact CG2-CD2 4.19Å; I393-F436 HydrophobicContact CD1-CE1 4.31Å
394	I	86.4	Confident	89.3	Confident	11 Å²	11	54.8 Å²	54.8	6%	0.056	26%	0.26	C	S	.	.	H	α-helix	trans	-63.3	-32.9	-175	-148.2	174.7	0	0	0	112.7	T390 L391 G398 R399 T402 A443 V446	T390-I394 WeakPolarHBondContact O-CB 3.4Å; T390-I394 PolarHBondContact O-N 3.08Å; L391-I394 WeakPolarHBondContact O-CG2 3.27Å; I394-G398 WeakPolarHBondContact O-CA 3.21Å; I394-G398 PolarHBondContact O-N 3.32Å; I394-R399 HydrophobicContact CD1-CG 3.97Å; I394-R399 HydrophobicContact CG1-CB 4.45Å; I394-R399 HydrophobicContact CG1-CG 3.95Å; I394-R399 PolarHBondContact O-NH1 3.1Å; I394-T402 WeakPolarHBondContact CA-OG1 3.43Å; I394-T402 HydrophobicContact CB-CG2 4.27Å; I394-T402 HydrophobicContact CG1-CG2 4.3Å; I394-A443 HydrophobicContact CD1-CB 3.92Å; I394-V446 HydrophobicContact CD1-CB 4.48Å
395	D	83.9	Confident	89.5	Confident	102 Å²	102	54.4 Å²	54.4	55%	0.545	26%	0.261	S	S	.	.	H	α-helix	trans	-78.5	-29.8	176.6	-74.7	-19.5	0	0	0	112.2	I393 R399 K513	I393-D395 VanDerWaalsContact C-N 3.26Å; I393-D395 PolarHBondContact O-N 3.43Å; D395-R399 IonicContact OD1-NH1 2.73Å; D395-K513 WeakPolarHBondContact O-CE 3.33Å; D395-K513 PolarHBondContact O-NZ 2.92Å
396	R	86.8	Confident	89.7	Confident	171 Å²	171	52 Å²	52	65%	0.645	25%	0.245	S	C	*	.	H	α-helix	trans	-82.9	-56.4	178.8	-69.1	-68	-172	117.6	-1.9	112.3	W392 I393 K513	W392-R396 HydrophobicContact CZ2-CG 4.44Å; W392-R396 WeakPolarHBondContact O-CG 3.34Å; W392-R396 PolarHBondContact O-N 3.49Å; I393-R396 PolarHBondContact O-N 2.8Å; R396-K513 PolarHBondContact O-NZ 3.17Å
397	L	87.1	Confident	90	Very high	84 Å²	84	51.8 Å²	51.8	44%	0.44	24%	0.243	S	C	.	.	H	α-helix	trans	-88.3	-17.1	-171.8	-63.4	-175.5	0	0	0	114	I393 K401 L405	I393-L397 HydrophobicContact CG2-CB 4.27Å; I393-L397 HydrophobicContact CG2-CD1 3.63Å; I393-L397 HydrophobicContact CG2-CG 4.04Å; I393-L397 PolarHBondContact O-N 3.43Å; L397-K401 HydrophobicContact CB-CB 4.19Å; L397-L405 HydrophobicContact CD1-CD2 4.04Å
398	G	87.4	Confident	90.6	Very high	0 Å²	0	54.5 Å²	54.5	0%	0	26%	0.259	C	S	.	.			trans	88.7	167.1	-170.2	0	0	0	0	0	112.1	I394 T402	I394-G398 WeakPolarHBondContact O-CA 3.21Å; I394-G398 PolarHBondContact O-N 3.32Å; G398-T402 VanDerWaalsContact O-CB 3.31Å; G398-T402 WeakPolarHBondContact O-CB 3.28Å; G398-T402 PolarHBondContact O-N 2.88Å; G398-T402 PolarHBondContact O-OG1 3.27Å
399	R	88.3	Confident	90.9	Very high	33 Å²	33	50.4 Å²	50.4	13%	0.125	24%	0.238	C	C	.	.	H	α-helix	trans	-72.6	-44.8	-167.8	-72.9	65.8	170.8	136.7	1.8	110.8	I394 D395 T402 M403 V446 Y447 E450 E511 T512	I394-R399 HydrophobicContact CD1-CG 3.97Å; I394-R399 HydrophobicContact CG1-CB 4.45Å; I394-R399 HydrophobicContact CG1-CG 3.95Å; I394-R399 PolarHBondContact O-NH1 3.1Å; D395-R399 IonicContact OD1-NH1 2.73Å; R399-T402 PolarHBondContact O-N 3.04Å; R399-M403 WeakPolarHBondContact O-CG 3.28Å; R399-M403 PolarHBondContact O-N 3.48Å; R399-V446 HydrophobicContact CG-CG1 4.46Å; R399-Y447 HydrophobicContact CB-CD2 3.64Å; R399-Y447 HydrophobicContact CB-CG 4.38Å; R399-Y447 HydrophobicContact CG-CD2 4.4Å; R399-E450 IonicContact NE-OE1 3.26Å; R399-E450 IonicContact NE-OE2 3.32Å; R399-E450 PolarHBondContact NE-OE2 3.26Å; R399-E450 IonicContact NH2-OE1 2.84Å; R399-E511 PolarHBondContact N-OE1 2.9Å; R399-T512 WeakPolarHBondContact CD-OG1 3.45Å; R399-T512 WeakPolarHBondContact CG-OG1 3.26Å
400	K	91.8	Very high	91.2	Very high	48 Å²	48	47.4 Å²	47.4	21%	0.209	22%	0.22	C	C	.	.	H	α-helix	trans	-61	-49.7	-177.2	-175.1	-176.9	168.5	-179.4	0	112.3	T402 M403 A404 S505 C506 L508 E511	K400-T402 VanDerWaalsContact C-N 3.33Å; K400-M403 PolarHBondContact O-N 2.95Å; K400-A404 PolarHBondContact O-N 3.4Å; K400-A404 VanDerWaalsContact O-N 3.16Å; K400-S505 WeakPolarHBondContact CE-O 3.27Å; K400-S505 WeakPolarHBondContact CG-O 3.34Å; K400-C506 WeakPolarHBondContact CE-O 3.04Å; K400-C506 PolarHBondContact NZ-O 3.26Å; K400-L508 HydrophobicContact CD-CB 4.09Å; K400-L508 WeakPolarHBondContact CE-O 3.44Å; K400-L508 HydrophobicContact CG-CB 4.17Å; K400-L508 HydrophobicContact CG-CD1 4.44Å; K400-L508 PolarHBondContact NZ-O 3.41Å; K400-E511 VanDerWaalsContact CB-OE2 3.23Å; K400-E511 WeakPolarHBondContact CB-OE2 3.4Å; K400-E511 PolarHBondContact N-OE2 3.07Å
401	K	92.7	Very high	91.6	Very high	136 Å²	136	47.3 Å²	47.3	59%	0.591	22%	0.219	S	C	*	.	H	α-helix	trans	-68.3	-34.4	-179.8	-65	-174.9	-175.2	175.1	0	112	L397 A404 L405	L397-K401 HydrophobicContact CB-CB 4.19Å; K401-A404 PolarHBondContact O-N 3.05Å; K401-L405 VanDerWaalsContact O-CB 3.31Å; K401-L405 WeakPolarHBondContact O-CB 2.97Å; K401-L405 PolarHBondContact O-N 3.05Å
402	T	93.4	Very high	92.1	Very high	0 Å²	0	50.9 Å²	50.9	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-64.1	-46.3	176.3	-57.7	0	0	0	0	111.2	T390 I393 I394 G398 R399 K400 A404 L405 C406 A443	T390-T402 HydrophobicContact CG2-CG2 3.91Å; I393-T402 HydrophobicContact CB-CG2 4.33Å; I393-T402 HydrophobicContact CG2-CG2 3.87Å; I394-T402 WeakPolarHBondContact CA-OG1 3.43Å; I394-T402 HydrophobicContact CB-CG2 4.27Å; I394-T402 HydrophobicContact CG1-CG2 4.3Å; G398-T402 VanDerWaalsContact O-CB 3.31Å; G398-T402 WeakPolarHBondContact O-CB 3.28Å; G398-T402 PolarHBondContact O-N 2.88Å; G398-T402 PolarHBondContact O-OG1 3.27Å; R399-T402 PolarHBondContact O-N 3.04Å; K400-T402 VanDerWaalsContact C-N 3.33Å; T402-A404 PolarHBondContact O-N 2.88Å; T402-L405 PolarHBondContact O-N 3.28Å; T402-C406 PolarHBondContact O-N 3.36Å; T402-C406 PolarHBondContact O-SG 2.84Å; T402-A443 HydrophobicContact CG2-CB 4.47Å
403	M	93.9	Very high	92.4	Very high	0 Å²	0	43.5 Å²	43.5	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-58.3	-47.9	174.7	-70.4	-175.6	-68.3	0	0	111.7	I323 R399 K400 L405 C406 F407 A443 A444 Y447 L508	I323-M403 HydrophobicContact CG2-SD 4.45Å; R399-M403 WeakPolarHBondContact O-CG 3.28Å; R399-M403 PolarHBondContact O-N 3.48Å; K400-M403 PolarHBondContact O-N 2.95Å; M403-L405 PolarHBondContact O-N 2.93Å; M403-C406 PolarHBondContact O-N 3.24Å; M403-F407 WeakPolarHBondContact O-CD2 3.45Å; M403-F407 PolarHBondContact O-N 3.29Å; M403-A443 HydrophobicContact CG-CB 3.55Å; M403-A444 HydrophobicContact SD-CB 4.17Å; M403-Y447 HydrophobicContact CE-CD1 3.82Å; M403-Y447 HydrophobicContact CE-CD2 4Å; M403-Y447 HydrophobicContact CE-CE1 4.27Å; M403-Y447 HydrophobicContact CE-CE2 4.43Å; M403-Y447 HydrophobicContact CE-CG 3.65Å; M403-L508 HydrophobicContact CE-CD1 3.6Å
404	A	95.8	Very high	92.4	Very high	9 Å²	9	42.7 Å²	42.7	7%	0.074	20%	0.202	C	C	.	.	H	α-helix	trans	-60.4	-44.1	178.2	0	0	0	0	0	112.4	K400 K401 T402 C406 F407 V408	K400-A404 PolarHBondContact O-N 3.4Å; K400-A404 VanDerWaalsContact O-N 3.16Å; K401-A404 PolarHBondContact O-N 3.05Å; T402-A404 PolarHBondContact O-N 2.88Å; A404-C406 PolarHBondContact O-N 3.05Å; A404-F407 PolarHBondContact O-N 3.32Å; A404-V408 WeakPolarHBondContact O-CG2 3.15Å; A404-V408 PolarHBondContact O-N 3.48Å
405	L	96	Very high	92.6	Very high	58 Å²	58	45.8 Å²	45.8	30%	0.304	22%	0.218	S	C	.	.	H	α-helix	trans	-60.9	-44	178.1	-179.1	65	0	0	0	111.8	I393 L397 K401 T402 M403 F407 V408 I409	I393-L405 HydrophobicContact CD1-CD2 4.32Å; I393-L405 HydrophobicContact CG2-CD2 4.19Å; L397-L405 HydrophobicContact CD1-CD2 4.04Å; K401-L405 VanDerWaalsContact O-CB 3.31Å; K401-L405 WeakPolarHBondContact O-CB 2.97Å; K401-L405 PolarHBondContact O-N 3.05Å; T402-L405 PolarHBondContact O-N 3.28Å; M403-L405 PolarHBondContact O-N 2.93Å; L405-F407 PolarHBondContact O-N 3.24Å; L405-V408 PolarHBondContact O-N 3.23Å; L405-I409 HydrophobicContact CD1-CD1 3.8Å; L405-I409 HydrophobicContact CD1-CG1 4.16Å; L405-I409 HydrophobicContact CD2-CD1 4.44Å; L405-I409 HydrophobicContact CG-CD1 3.77Å; L405-I409 HydrophobicContact CG-CG1 4.45Å; L405-I409 WeakPolarHBondContact O-CG1 3.14Å; L405-I409 PolarHBondContact O-N 3.15Å
406	C	95.6	Very high	92.9	Very high	2 Å²	2	43.7 Å²	43.7	1%	0.014	21%	0.206	C	C	.	.	H	α-helix	trans	-58.7	-46.7	178.3	-68.2	0	0	0	0	111.7	T402 M403 A404 I409 F410 F436	T402-C406 PolarHBondContact O-N 3.36Å; T402-C406 PolarHBondContact O-SG 2.84Å; M403-C406 PolarHBondContact O-N 3.24Å; A404-C406 PolarHBondContact O-N 3.05Å; C406-I409 PolarHBondContact O-N 3.16Å; C406-F410 WeakPolarHBondContact O-CB 3.47Å; C406-F410 PolarHBondContact O-N 3.49Å; C406-F436 HydrophobicContact CB-CB 4.49Å; C406-F436 VanDerWaalsContact CB-O 3.29Å; C406-F436 WeakPolarHBondContact CB-O 3.18Å
407	F	97.1	Very high	92.9	Very high	0 Å²	0	36.5 Å²	36.5	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-66.1	-38.5	177.1	-75.6	-55.7	0	0	0	113.4	I323 N327 M403 A404 L405 S411 I437 C498 A501 A502	I323-F407 HydrophobicContact CG2-CE2 3.97Å; I323-F407 HydrophobicContact CG2-CZ 4.16Å; N327-F407 HydrophobicContact CB-CZ 4.28Å; N327-F407 VanDerWaalsContact CG-CZ 3.47Å; N327-F407 VanDerWaalsContact OD1-CE1 3.24Å; N327-F407 WeakPolarHBondContact OD1-CE1 3.37Å; N327-F407 WeakPolarHBondContact OD1-CZ 3.4Å; M403-F407 WeakPolarHBondContact O-CD2 3.45Å; M403-F407 PolarHBondContact O-N 3.29Å; A404-F407 PolarHBondContact O-N 3.32Å; L405-F407 PolarHBondContact O-N 3.24Å; F407-S411 WeakPolarHBondContact O-CB 3.46Å; F407-S411 PolarHBondContact O-N 3.17Å; F407-S411 PolarHBondContact O-OG 2.51Å; F407-I437 HydrophobicContact CD1-CD1 3.97Å; F407-I437 HydrophobicContact CE1-CD1 3.83Å; F407-C498 HydrophobicContact CB-CB 4.44Å; F407-C498 WeakPolarHBondContact CB-O 3.2Å; F407-C498 HydrophobicContact CD1-CB 4Å; F407-A501 HydrophobicContact CD1-CB 4.05Å; F407-A501 HydrophobicContact CD2-CB 3.91Å; F407-A501 HydrophobicContact CE1-CB 3.92Å; F407-A501 HydrophobicContact CE2-CB 3.78Å; F407-A501 HydrophobicContact CG-CB 4.04Å; F407-A501 HydrophobicContact CZ-CB 3.78Å; F407-A502 HydrophobicContact CB-CB 3.76Å
408	V	97.4	Very high	92.8	Very high	69 Å²	69	35.7 Å²	35.7	42%	0.418	17%	0.174	S	C	.	.	H	α-helix	trans	-64.1	-46.1	176.7	168.9	0	0	0	0	110.7	A404 L405 S411 F412 A502	A404-V408 WeakPolarHBondContact O-CG2 3.15Å; A404-V408 PolarHBondContact O-N 3.48Å; L405-V408 PolarHBondContact O-N 3.23Å; V408-S411 PolarHBondContact O-N 3.47Å; V408-F412 WeakPolarHBondContact O-CB 3.29Å; V408-F412 PolarHBondContact O-N 3.41Å; V408-A502 HydrophobicContact CG2-CB 3.79Å
409	I	96.6	Very high	92.5	Very high	37 Å²	37	41.1 Å²	41.1	19%	0.19	20%	0.201	C	C	.	.	H	α-helix	trans	-65	-45.3	179.8	-66.4	169.5	0	0	0	110.6	L405 C406 S411 F412 C413 I432 F436	L405-I409 HydrophobicContact CD1-CD1 3.8Å; L405-I409 HydrophobicContact CD1-CG1 4.16Å; L405-I409 HydrophobicContact CD2-CD1 4.44Å; L405-I409 HydrophobicContact CG-CD1 3.77Å; L405-I409 HydrophobicContact CG-CG1 4.45Å; L405-I409 WeakPolarHBondContact O-CG1 3.14Å; L405-I409 PolarHBondContact O-N 3.15Å; C406-I409 PolarHBondContact O-N 3.16Å; I409-S411 VanDerWaalsContact C-N 3.31Å; I409-S411 PolarHBondContact O-N 2.77Å; I409-F412 PolarHBondContact O-N 3.44Å; I409-C413 PolarHBondContact O-N 3.07Å; I409-C413 PolarHBondContact O-SG 2.73Å; I409-C413 VanDerWaalsContact O-SG 3.39Å; I409-I432 HydrophobicContact CG2-CG2 3.84Å; I409-F436 HydrophobicContact CB-CB 4.4Å; I409-F436 HydrophobicContact CB-CD1 4.38Å; I409-F436 HydrophobicContact CB-CD2 4.22Å; I409-F436 HydrophobicContact CB-CG 4.07Å; I409-F436 HydrophobicContact CD1-CD1 3.67Å; I409-F436 HydrophobicContact CD1-CD2 4.26Å; I409-F436 HydrophobicContact CD1-CE1 3.36Å; I409-F436 HydrophobicContact CD1-CE2 4.01Å; I409-F436 HydrophobicContact CD1-CG 4.11Å; I409-F436 HydrophobicContact CD1-CZ 3.55Å; I409-F436 HydrophobicContact CG2-CB 4.28Å; I409-F436 HydrophobicContact CG2-CD1 4.45Å; I409-F436 HydrophobicContact CG2-CD2 3.44Å; I409-F436 VanDerWaalsContact CG2-CD2 3.44Å; I409-F436 HydrophobicContact CG2-CE2 3.83Å; I409-F436 HydrophobicContact CG2-CG 3.8Å; I409-F436 HydrophobicContact CG2-CZ 4.48Å
410	F	96.1	Very high	91.9	Very high	2 Å²	2	42.9 Å²	42.9	1%	0.009	22%	0.218	C	C	.	.	H	α-helix	trans	-56.9	-45.8	174.5	175.2	-87.3	0	0	0	111.9	L334 C406 C413 S414 A433 I437 C498	L334-F410 HydrophobicContact CB-CE2 4.16Å; L334-F410 HydrophobicContact CD1-CE2 4.04Å; L334-F410 HydrophobicContact CD2-CE2 4.04Å; L334-F410 HydrophobicContact CG-CE2 4.31Å; C406-F410 WeakPolarHBondContact O-CB 3.47Å; C406-F410 PolarHBondContact O-N 3.49Å; F410-C413 PolarHBondContact O-N 3.47Å; F410-S414 WeakPolarHBondContact CE1-OG 3.49Å; F410-S414 WeakPolarHBondContact O-CB 3.45Å; F410-S414 PolarHBondContact O-N 3.12Å; F410-S414 PolarHBondContact O-OG 3.05Å; F410-A433 HydrophobicContact CD2-CB 3.84Å; F410-A433 HydrophobicContact CE2-CB 4.2Å; F410-I437 HydrophobicContact CD2-CB 3.68Å; F410-I437 HydrophobicContact CD2-CD1 4.42Å; F410-I437 HydrophobicContact CD2-CG1 4.1Å; F410-I437 HydrophobicContact CD2-CG2 4.07Å; F410-I437 HydrophobicContact CE2-CB 4.18Å; F410-I437 HydrophobicContact CE2-CG1 4.31Å; F410-I437 HydrophobicContact CE2-CG2 4.23Å; F410-I437 HydrophobicContact CG-CB 4.32Å; F410-I437 HydrophobicContact CG-CD1 4.36Å; F410-C498 HydrophobicContact CD1-CB 3.82Å; F410-C498 WeakPolarHBondContact CD1-SG 3.35Å; F410-C498 HydrophobicContact CE1-CB 4.32Å; F410-C498 VanDerWaalsContact CE1-SG 3.52Å
411	S	95.8	Very high	91.3	Very high	1 Å²	1	42.4 Å²	42.4	1%	0.007	22%	0.219	C	C	.	.	H	α-helix	trans	-64.9	-41.1	179.6	-55.6	0	0	0	0	111.5	F407 V408 I409 S414 L415 S495 C498 L499	F407-S411 WeakPolarHBondContact O-CB 3.46Å; F407-S411 PolarHBondContact O-N 3.17Å; F407-S411 PolarHBondContact O-OG 2.51Å; V408-S411 PolarHBondContact O-N 3.47Å; I409-S411 VanDerWaalsContact C-N 3.31Å; I409-S411 PolarHBondContact O-N 2.77Å; S411-S414 PolarHBondContact O-N 2.96Å; S411-L415 WeakPolarHBondContact O-CB 3.15Å; S411-L415 VanDerWaalsContact O-CG 3.24Å; S411-L415 WeakPolarHBondContact O-CG 3.41Å; S411-L415 PolarHBondContact O-N 3.32Å; S411-S495 PolarHBondContact OG-O 3.34Å; S411-C498 WeakPolarHBondContact OG-CB 3.24Å; S411-L499 PolarHBondContact OG-N 2.8Å
412	F	95.6	Very high	90.9	Very high	126 Å²	126	38.2 Å²	38.2	55%	0.553	22%	0.215	S	C	*	.	H	α-helix	trans	-62.4	-49.2	176.3	178.5	-104.5	0	0	0	111.5	V408 I409 S414 L415 L416	V408-F412 WeakPolarHBondContact O-CB 3.29Å; V408-F412 PolarHBondContact O-N 3.41Å; I409-F412 PolarHBondContact O-N 3.44Å; F412-S414 VanDerWaalsContact C-N 3.31Å; F412-S414 PolarHBondContact O-N 2.92Å; F412-L415 PolarHBondContact O-N 3.4Å; F412-L416 HydrophobicContact CD1-CD1 4.04Å; F412-L416 HydrophobicContact CE1-CD1 3.51Å; F412-L416 HydrophobicContact CE1-CG 4.25Å; F412-L416 HydrophobicContact CE2-CD2 4.48Å; F412-L416 HydrophobicContact CE2-CG 4.47Å; F412-L416 HydrophobicContact CZ-CD1 3.78Å; F412-L416 HydrophobicContact CZ-CD2 4.29Å; F412-L416 HydrophobicContact CZ-CG 4.19Å; F412-L416 WeakPolarHBondContact O-CG 3.31Å; F412-L416 PolarHBondContact O-N 2.84Å
413	C	94.1	Very high	90.5	Very high	5 Å²	5	42 Å²	42	3%	0.034	23%	0.229	C	C	.	.	H	α-helix	trans	-59	-43	175.3	-69.3	0	0	0	0	111.8	I409 F410 L416 L417 L429 I432 A433	I409-C413 PolarHBondContact O-N 3.07Å; I409-C413 PolarHBondContact O-SG 2.73Å; I409-C413 VanDerWaalsContact O-SG 3.39Å; F410-C413 PolarHBondContact O-N 3.47Å; C413-L416 PolarHBondContact O-N 3.2Å; C413-L417 PolarHBondContact O-N 2.92Å; C413-L429 HydrophobicContact CB-CD2 4.4Å; C413-I432 VanDerWaalsContact SG-CG2 3.54Å; C413-A433 HydrophobicContact CB-CB 4Å
414	S	89.5	Confident	90.2	Very high	3 Å²	3	48.5 Å²	48.5	2%	0.021	26%	0.264	C	S	.	.	H	α-helix	trans	-66.5	-36.3	178.3	-57.5	0	0	0	0	112.8	F410 S411 F412 L417	F410-S414 WeakPolarHBondContact CE1-OG 3.49Å; F410-S414 WeakPolarHBondContact O-CB 3.45Å; F410-S414 PolarHBondContact O-N 3.12Å; F410-S414 PolarHBondContact O-OG 3.05Å; S411-S414 PolarHBondContact O-N 2.96Å; F412-S414 VanDerWaalsContact C-N 3.31Å; F412-S414 PolarHBondContact O-N 2.92Å; S414-L417 WeakPolarHBondContact O-CB 3.24Å; S414-L417 PolarHBondContact O-N 2.86Å
415	L	90.4	Very high	90	Very high	75 Å²	75	51.5 Å²	51.5	39%	0.393	28%	0.281	S	S	.	.	H	α-helix	trans	-70	-34.5	175.2	-75.9	169	0	0	0	112	S411 F412 L417 F418 L499	S411-L415 WeakPolarHBondContact O-CB 3.15Å; S411-L415 VanDerWaalsContact O-CG 3.24Å; S411-L415 WeakPolarHBondContact O-CG 3.41Å; S411-L415 PolarHBondContact O-N 3.32Å; F412-L415 PolarHBondContact O-N 3.4Å; L415-L417 PolarHBondContact O-N 3.04Å; L415-F418 HydrophobicContact CD2-CD2 4.31Å; L415-F418 HydrophobicContact CD2-CE2 3.88Å; L415-F418 HydrophobicContact CD2-CZ 4.21Å; L415-F418 VanDerWaalsContact O-CB 3.26Å; L415-F418 WeakPolarHBondContact O-CB 3.08Å; L415-F418 WeakPolarHBondContact O-CD2 3.49Å; L415-F418 PolarHBondContact O-N 2.8Å; L415-L499 HydrophobicContact CD1-CD1 4.5Å
416	L	89.8	Confident	89.7	Confident	58 Å²	58	49.5 Å²	49.5	30%	0.304	27%	0.27	S	S	.	.	H	α-helix	trans	-63	-26.7	174.3	-71.4	178.6	0	0	0	112.4	F412 C413 F418 I419 L429	F412-L416 HydrophobicContact CD1-CD1 4.04Å; F412-L416 HydrophobicContact CE1-CD1 3.51Å; F412-L416 HydrophobicContact CE1-CG 4.25Å; F412-L416 HydrophobicContact CE2-CD2 4.48Å; F412-L416 HydrophobicContact CE2-CG 4.47Å; F412-L416 HydrophobicContact CZ-CD1 3.78Å; F412-L416 HydrophobicContact CZ-CD2 4.29Å; F412-L416 HydrophobicContact CZ-CG 4.19Å; F412-L416 WeakPolarHBondContact O-CG 3.31Å; F412-L416 PolarHBondContact O-N 2.84Å; C413-L416 PolarHBondContact O-N 3.2Å; L416-F418 PolarHBondContact O-N 2.84Å; L416-I419 PolarHBondContact O-N 3.33Å; L416-I419 VanDerWaalsContact O-N 3.11Å; L416-L429 HydrophobicContact CB-CD1 3.95Å; L416-L429 HydrophobicContact CB-CD2 4.24Å; L416-L429 HydrophobicContact CD1-CD2 3.76Å
417	L	86.3	Confident	89.5	Confident	20 Å²	20	50 Å²	50	11%	0.105	27%	0.273	C	S	.	.	T	Hydrogen-bonded Turn	trans	-69.3	-7.2	173.5	-59.9	178	0	0	0	113.8	L341 C413 S414 L415 I419 V421 L426 L429 L430 L491	L341-L417 HydrophobicContact CD2-CD1 4.25Å; C413-L417 PolarHBondContact O-N 2.92Å; S414-L417 WeakPolarHBondContact O-CB 3.24Å; S414-L417 PolarHBondContact O-N 2.86Å; L415-L417 PolarHBondContact O-N 3.04Å; L417-I419 PolarHBondContact O-N 3.13Å; L417-V421 HydrophobicContact CD2-CG2 4.12Å; L417-L426 HydrophobicContact CD1-CD1 4.45Å; L417-L426 HydrophobicContact CD2-CD1 3.5Å; L417-L426 VanDerWaalsContact CD2-CD1 3.5Å; L417-L429 HydrophobicContact CD2-CB 4.01Å; L417-L429 HydrophobicContact CD2-CD1 3.59Å; L417-L429 HydrophobicContact CD2-CG 4.46Å; L417-L429 HydrophobicContact CG-CD1 4.35Å; L417-L430 HydrophobicContact CD1-CD2 4.01Å; L417-L491 HydrophobicContact CB-CD1 3.68Å; L417-L491 HydrophobicContact CB-CD2 4.29Å; L417-L491 HydrophobicContact CD1-CD2 4.07Å
418	F	84.3	Confident	89.4	Confident	68 Å²	68	54.7 Å²	54.7	30%	0.298	30%	0.298	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.5	-24.6	168.8	-78.7	-123.6	0	0	0	111.7	L415 L416 Y488 L491 A492	L415-F418 HydrophobicContact CD2-CD2 4.31Å; L415-F418 HydrophobicContact CD2-CE2 3.88Å; L415-F418 HydrophobicContact CD2-CZ 4.21Å; L415-F418 VanDerWaalsContact O-CB 3.26Å; L415-F418 WeakPolarHBondContact O-CB 3.08Å; L415-F418 WeakPolarHBondContact O-CD2 3.49Å; L415-F418 PolarHBondContact O-N 2.8Å; L416-F418 PolarHBondContact O-N 2.84Å; F418-Y488 HydrophobicContact CB-CD1 4.36Å; F418-Y488 HydrophobicContact CB-CE1 4.49Å; F418-Y488 AromaticContact CD1-CD1 3.96Å; F418-Y488 HydrophobicContact CD1-CD1 3.96Å; F418-Y488 HydrophobicContact CG-CD1 4.2Å; F418-Y488 WeakPolarHBondContact CZ-O 3.33Å; F418-Y488 VanDerWaalsContact O-CE1 3.26Å; F418-Y488 WeakPolarHBondContact O-CE1 3.07Å; F418-L491 HydrophobicContact CD2-CB 4.07Å; F418-L491 HydrophobicContact CD2-CD1 4.31Å; F418-L491 HydrophobicContact CE2-CB 3.49Å; F418-L491 VanDerWaalsContact CE2-CB 3.49Å; F418-L491 HydrophobicContact CZ-CB 4.22Å; F418-A492 HydrophobicContact CZ-CB 3.84Å
419	I	83	Confident	89.2	Confident	114 Å²	114	52.2 Å²	52.2	59%	0.585	28%	0.282	S	S	*	.	S	Bend	trans	-86.9	140.4	174.7	-55	173.8	0	0	0	107.1	L416 L417 V421	L416-I419 PolarHBondContact O-N 3.33Å; L416-I419 VanDerWaalsContact O-N 3.11Å; L417-I419 PolarHBondContact O-N 3.13Å; I419-V421 PolarHBondContact O-N 3.31Å; I419-V421 VanDerWaalsContact O-N 3.08Å
420	C	73.9	Confident	89.1	Confident	70 Å²	70	50.5 Å²	50.5	47%	0.473	27%	0.273	S	S	.	.			trans	-63.8	112.2	173.3	-175.8	0	0	0	0	109.8	C348	C348-C420 WeakPolarHBondContact CA-SG 3.45Å; C348-C420 HydrophobicContact CB-CB 4.43Å; C348-C420 WeakPolarHBondContact CB-SG 3.06Å; C348-C420 WeakPolarHBondContact SG-CA 3.48Å; C348-C420 WeakPolarHBondContact SG-CB 3.38Å; C348-C420 CovalentContact SG-SG 2.02Å; C348-C420 PolarHBondContact SG-SG 3.44Å
421	V	80.3	Confident	89.1	Confident	37 Å²	37	53.1 Å²	53.1	22%	0.224	29%	0.285	C	S	.	.			trans	-116.7	148.7	-176.9	-70.7	0	0	0	0	110.5	L417 I419 V425 L426	L417-V421 HydrophobicContact CD2-CG2 4.12Å; I419-V421 PolarHBondContact O-N 3.31Å; I419-V421 VanDerWaalsContact O-N 3.08Å; V421-V425 HydrophobicContact CB-CB 4.12Å; V421-V425 HydrophobicContact CB-CG1 3.94Å; V421-V425 HydrophobicContact CG1-CG1 3.95Å; V421-L426 HydrophobicContact CG2-CB 4.19Å
422	G	83.6	Confident	89.1	Confident	49 Å²	49	55.6 Å²	55.6	51%	0.505	30%	0.298	S	S	.	.			trans	-69.1	159.6	174.3	0	0	0	0	0	112.3	N424 V425 L426	G422-N424 PolarHBondContact O-N 3.1Å; G422-V425 PolarHBondContact O-N 2.99Å; G422-L426 PolarHBondContact O-N 3.21Å
423	R	84.8	Confident	89.1	Confident	79 Å²	79	49.7 Å²	49.7	30%	0.298	27%	0.272	S	S	.	.	H	α-helix	trans	-49.1	-48.6	-177.2	-172.2	173.5	179.2	108.3	7.7	113.8	E371 D372 D375 V425 L426 T427	E371-R423 PolarHBondContact O-NH2 3.37Å; E371-R423 VanDerWaalsContact O-NH2 3.08Å; D372-R423 VanDerWaalsContact CA-NH2 3.29Å; D372-R423 VanDerWaalsContact N-NH2 3.12Å; D372-R423 IonicContact OD1-CZ 3.05Å; D372-R423 VanDerWaalsContact OD1-CZ 3.26Å; D372-R423 IonicContact OD1-NH1 3.98Å; D372-R423 PolarHBondContact OD1-NH1 3.37Å; D372-R423 IonicContact OD1-NH2 2.66Å; D372-R423 PolarHBondContact OD1-NH2 3.36Å; D375-R423 IonicContact OD2-CZ 3.59Å; D375-R423 IonicContact OD2-NE 2.71Å; D375-R423 PolarHBondContact OD2-NE 2.62Å; D375-R423 IonicContact OD2-NH2 2.81Å; D375-R423 PolarHBondContact OD2-NH2 3.24Å; R423-V425 VanDerWaalsContact C-N 3.3Å; R423-V425 PolarHBondContact O-N 3.34Å; R423-L426 WeakPolarHBondContact O-CB 3.24Å; R423-L426 PolarHBondContact O-N 3.41Å; R423-L426 VanDerWaalsContact O-N 3.17Å; R423-T427 PolarHBondContact O-N 3.27Å; R423-T427 PolarHBondContact O-OG1 2.83Å
424	N	88.8	Confident	89.2	Confident	137 Å²	137	49.5 Å²	49.5	73%	0.733	27%	0.271	S	S	*	.	H	α-helix	trans	-61.5	-37	178.8	-62.3	-11.1	0	0	0	113.2	G422 L428	G422-N424 PolarHBondContact O-N 3.1Å; N424-L428 WeakPolarHBondContact O-CB 3.21Å; N424-L428 PolarHBondContact O-N 2.85Å; N424-L428 VanDerWaalsContact O-N 3.07Å
425	V	90.5	Very high	89.4	Confident	71 Å²	71	49.7 Å²	49.7	43%	0.43	27%	0.272	S	S	.	.	H	α-helix	trans	-74.2	-37.8	178.6	178.3	0	0	0	0	110.1	V421 G422 R423 L428 L429	V421-V425 HydrophobicContact CB-CB 4.12Å; V421-V425 HydrophobicContact CB-CG1 3.94Å; V421-V425 HydrophobicContact CG1-CG1 3.95Å; G422-V425 PolarHBondContact O-N 2.99Å; R423-V425 VanDerWaalsContact C-N 3.3Å; R423-V425 PolarHBondContact O-N 3.34Å; V425-L428 PolarHBondContact O-N 2.7Å; V425-L429 HydrophobicContact CG1-CD1 4.03Å; V425-L429 HydrophobicContact CG1-CG 4.31Å; V425-L429 WeakPolarHBondContact O-CB 3.5Å; V425-L429 VanDerWaalsContact O-CG 3.27Å; V425-L429 WeakPolarHBondContact O-CG 3.23Å; V425-L429 PolarHBondContact O-N 2.7Å
426	L	90.1	Very high	89.7	Confident	16 Å²	16	47.9 Å²	47.9	8%	0.084	26%	0.261	C	S	.	.	H	α-helix	trans	-57.4	-53.6	172	173.2	62.9	0	0	0	111	L341 F342 L417 V421 G422 R423 L428 L429 L430	L341-L426 HydrophobicContact CD2-CD1 3.56Å; L341-L426 HydrophobicContact CG-CD1 4.14Å; L341-L426 HydrophobicContact CG-CD2 4.24Å; F342-L426 HydrophobicContact CD1-CD2 3.87Å; F342-L426 HydrophobicContact CE1-CD2 3.78Å; F342-L426 HydrophobicContact CE1-CG 4Å; L417-L426 HydrophobicContact CD1-CD1 4.45Å; L417-L426 HydrophobicContact CD2-CD1 3.5Å; L417-L426 VanDerWaalsContact CD2-CD1 3.5Å; V421-L426 HydrophobicContact CG2-CB 4.19Å; G422-L426 PolarHBondContact O-N 3.21Å; R423-L426 WeakPolarHBondContact O-CB 3.24Å; R423-L426 PolarHBondContact O-N 3.41Å; R423-L426 VanDerWaalsContact O-N 3.17Å; L426-L428 VanDerWaalsContact C-N 3.3Å; L426-L428 PolarHBondContact O-N 3.39Å; L426-L429 PolarHBondContact O-N 3.25Å; L426-L429 VanDerWaalsContact O-N 3.17Å; L426-L430 HydrophobicContact CD1-CD1 3.84Å; L426-L430 HydrophobicContact CD1-CG 4.05Å; L426-L430 HydrophobicContact CG-CD1 4.03Å; L426-L430 WeakPolarHBondContact O-CG 3.37Å; L426-L430 PolarHBondContact O-N 3.05Å
427	T	92	Very high	89.9	Confident	12 Å²	12	45.1 Å²	45.1	7%	0.074	25%	0.247	C	C	.	.	H	α-helix	trans	-57.7	-42.8	177.9	-53.1	0	0	0	0	111.3	D375 W378 T379 R423 L430 F431	D375-T427 HydrophobicContact CB-CG2 4.19Å; D375-T427 VanDerWaalsContact CG-OG1 3.23Å; D375-T427 WeakPolarHBondContact OD1-CB 3.24Å; D375-T427 VanDerWaalsContact OD1-CG2 3.27Å; D375-T427 WeakPolarHBondContact OD1-CG2 3.2Å; D375-T427 PolarHBondContact OD1-OG1 3.16Å; W378-T427 HydrophobicContact CB-CG2 3.93Å; T379-T427 HydrophobicContact CG2-CG2 4.05Å; R423-T427 PolarHBondContact O-N 3.27Å; R423-T427 PolarHBondContact O-OG1 2.83Å; T427-L430 PolarHBondContact O-N 3.07Å; T427-F431 VanDerWaalsContact O-CB 3.24Å; T427-F431 WeakPolarHBondContact O-CB 3.43Å; T427-F431 PolarHBondContact O-N 3.4Å
428	L	94.3	Very high	90.2	Very high	100 Å²	100	44.7 Å²	44.7	52%	0.524	25%	0.246	S	C	.	.	H	α-helix	trans	-63.5	-43.1	176.8	-180	64.4	0	0	0	112.8	N424 V425 L426 F431 I432	N424-L428 WeakPolarHBondContact O-CB 3.21Å; N424-L428 PolarHBondContact O-N 2.85Å; N424-L428 VanDerWaalsContact O-N 3.07Å; V425-L428 PolarHBondContact O-N 2.7Å; L426-L428 VanDerWaalsContact C-N 3.3Å; L426-L428 PolarHBondContact O-N 3.39Å; L428-F431 WeakPolarHBondContact O-CB 3.44Å; L428-F431 PolarHBondContact O-N 2.88Å; L428-I432 HydrophobicContact CD1-CD1 4.21Å; L428-I432 HydrophobicContact CG-CD1 4.2Å; L428-I432 WeakPolarHBondContact O-CG1 3.49Å; L428-I432 PolarHBondContact O-N 3.43Å
429	L	94.3	Very high	90.5	Very high	16 Å²	16	41.5 Å²	41.5	8%	0.084	23%	0.232	C	C	.	.	H	α-helix	trans	-65.9	-41.7	178.3	-72.9	173.5	0	0	0	111.4	C413 L416 L417 V425 L426 I432 A433	C413-L429 HydrophobicContact CB-CD2 4.4Å; L416-L429 HydrophobicContact CB-CD1 3.95Å; L416-L429 HydrophobicContact CB-CD2 4.24Å; L416-L429 HydrophobicContact CD1-CD2 3.76Å; L417-L429 HydrophobicContact CD2-CB 4.01Å; L417-L429 HydrophobicContact CD2-CD1 3.59Å; L417-L429 HydrophobicContact CD2-CG 4.46Å; L417-L429 HydrophobicContact CG-CD1 4.35Å; V425-L429 HydrophobicContact CG1-CD1 4.03Å; V425-L429 HydrophobicContact CG1-CG 4.31Å; V425-L429 WeakPolarHBondContact O-CB 3.5Å; V425-L429 VanDerWaalsContact O-CG 3.27Å; V425-L429 WeakPolarHBondContact O-CG 3.23Å; V425-L429 PolarHBondContact O-N 2.7Å; L426-L429 PolarHBondContact O-N 3.25Å; L426-L429 VanDerWaalsContact O-N 3.17Å; L429-I432 PolarHBondContact O-N 2.95Å; L429-A433 VanDerWaalsContact O-CB 3.28Å; L429-A433 WeakPolarHBondContact O-CB 3.46Å; L429-A433 PolarHBondContact O-N 3.33Å
430	L	94	Very high	91	Very high	1 Å²	1	36 Å²	36	1%	0.005	20%	0.204	C	C	.	.	H	α-helix	trans	-67.1	-38.3	175.6	-67	176.6	0	0	0	111.9	L334 T338 F342 T379 L417 L426 T427 A433 R434	L334-L430 HydrophobicContact CD1-CD2 3.68Å; T338-L430 HydrophobicContact CG2-CD1 4.09Å; F342-L430 HydrophobicContact CE1-CD1 4.27Å; F342-L430 HydrophobicContact CE2-CD1 4.29Å; F342-L430 HydrophobicContact CZ-CD1 3.79Å; T379-L430 HydrophobicContact CG2-CB 3.65Å; L417-L430 HydrophobicContact CD1-CD2 4.01Å; L426-L430 HydrophobicContact CD1-CD1 3.84Å; L426-L430 HydrophobicContact CD1-CG 4.05Å; L426-L430 HydrophobicContact CG-CD1 4.03Å; L426-L430 WeakPolarHBondContact O-CG 3.37Å; L426-L430 PolarHBondContact O-N 3.05Å; T427-L430 PolarHBondContact O-N 3.07Å; L430-A433 PolarHBondContact O-N 3.24Å; L430-R434 VanDerWaalsContact O-CB 3.25Å; L430-R434 WeakPolarHBondContact O-CB 3.04Å; L430-R434 PolarHBondContact O-N 3.33Å
431	F	95.7	Very high	91.8	Very high	58 Å²	58	34 Å²	34	25%	0.254	19%	0.187	S	C	.	.	H	α-helix	trans	-56.2	-52	173.2	179.9	-78.9	0	0	0	110.9	W378 S382 P385 T427 L428 R434 A435	W378-F431 WeakPolarHBondContact O-CD2 3.37Å; W378-F431 WeakPolarHBondContact O-CE2 3.39Å; S382-F431 VanDerWaalsContact CA-CE2 3.48Å; S382-F431 VanDerWaalsContact CB-CG 3.49Å; S382-F431 WeakPolarHBondContact CB-O 3.43Å; S382-F431 PolarHBondContact OG-O 3.24Å; P385-F431 HydrophobicContact CG-CE1 4.45Å; P385-F431 HydrophobicContact CG-CZ 3.91Å; T427-F431 VanDerWaalsContact O-CB 3.24Å; T427-F431 WeakPolarHBondContact O-CB 3.43Å; T427-F431 PolarHBondContact O-N 3.4Å; L428-F431 WeakPolarHBondContact O-CB 3.44Å; L428-F431 PolarHBondContact O-N 2.88Å; F431-R434 PolarHBondContact O-N 3.24Å; F431-A435 WeakPolarHBondContact O-CB 2.98Å; F431-A435 PolarHBondContact O-N 2.88Å
432	I	96.3	Very high	92.1	Very high	53 Å²	53	32.8 Å²	32.8	27%	0.272	18%	0.179	S	C	.	.	H	α-helix	trans	-64.8	-48	179.7	-64.5	168.4	0	0	0	110	I409 C413 L428 L429 R434 A435 F436	I409-I432 HydrophobicContact CG2-CG2 3.84Å; C413-I432 VanDerWaalsContact SG-CG2 3.54Å; L428-I432 HydrophobicContact CD1-CD1 4.21Å; L428-I432 HydrophobicContact CG-CD1 4.2Å; L428-I432 WeakPolarHBondContact O-CG1 3.49Å; L428-I432 PolarHBondContact O-N 3.43Å; L429-I432 PolarHBondContact O-N 2.95Å; I432-R434 VanDerWaalsContact C-N 3.31Å; I432-R434 PolarHBondContact O-N 3.44Å; I432-A435 PolarHBondContact O-N 2.98Å; I432-F436 HydrophobicContact CG2-CD2 3.77Å; I432-F436 HydrophobicContact CG2-CE2 3.91Å; I432-F436 WeakPolarHBondContact O-CD2 3.23Å; I432-F436 PolarHBondContact O-N 3.13Å; I432-F436 VanDerWaalsContact O-N 3.12Å
433	A	95.7	Very high	92.4	Very high	2 Å²	2	30.5 Å²	30.5	2%	0.017	16%	0.155	C	C	.	.	H	α-helix	trans	-55.9	-46.6	178.8	0	0	0	0	0	111.6	L334 F410 C413 L429 L430 F436 I437	L334-A433 HydrophobicContact CD1-CB 4.31Å; L334-A433 HydrophobicContact CD2-CB 4.02Å; F410-A433 HydrophobicContact CD2-CB 3.84Å; F410-A433 HydrophobicContact CE2-CB 4.2Å; C413-A433 HydrophobicContact CB-CB 4Å; L429-A433 VanDerWaalsContact O-CB 3.28Å; L429-A433 WeakPolarHBondContact O-CB 3.46Å; L429-A433 PolarHBondContact O-N 3.33Å; L430-A433 PolarHBondContact O-N 3.24Å; A433-F436 PolarHBondContact O-N 2.99Å; A433-I437 WeakPolarHBondContact O-CB 2.9Å; A433-I437 VanDerWaalsContact O-CG2 3.28Å; A433-I437 WeakPolarHBondContact O-CG2 3.43Å; A433-I437 PolarHBondContact O-N 3.37Å
434	R	95.4	Very high	92.7	Very high	1 Å²	1	26.7 Å²	26.7	0%	0.004	14%	0.141	C	C	.	.	H	α-helix	trans	-65.3	-41.5	-179.8	-166.6	-175.5	-174	108.7	5.9	112.4	L334 T379 S382 E383 L430 F431 I432 F436 S438	L334-R434 HydrophobicContact CD2-CB 3.52Å; L334-R434 HydrophobicContact CD2-CG 4.07Å; T379-R434 WeakPolarHBondContact O-CD 3.18Å; S382-R434 WeakPolarHBondContact OG-CB 3.41Å; E383-R434 HydrophobicContact CG-CG 4.38Å; E383-R434 IonicContact OE1-CZ 3.12Å; E383-R434 VanDerWaalsContact OE1-CZ 3.24Å; E383-R434 IonicContact OE1-NE 2.71Å; E383-R434 PolarHBondContact OE1-NE 3.39Å; E383-R434 IonicContact OE1-NH2 2.72Å; E383-R434 PolarHBondContact OE1-NH2 2.96Å; L430-R434 VanDerWaalsContact O-CB 3.25Å; L430-R434 WeakPolarHBondContact O-CB 3.04Å; L430-R434 PolarHBondContact O-N 3.33Å; F431-R434 PolarHBondContact O-N 3.24Å; I432-R434 VanDerWaalsContact C-N 3.31Å; I432-R434 PolarHBondContact O-N 3.44Å; R434-F436 PolarHBondContact O-N 2.94Å; R434-S438 VanDerWaalsContact O-CB 3.27Å; R434-S438 WeakPolarHBondContact O-CB 3.36Å; R434-S438 PolarHBondContact O-N 2.97Å
435	A	95.1	Very high	92.6	Very high	7 Å²	7	22.8 Å²	22.8	6%	0.058	12%	0.116	C	C	.	.	H	α-helix	trans	-61	-46	180	0	0	0	0	0	111.2	S382 F431 I432 G439	S382-A435 WeakPolarHBondContact O-CB 2.84Å; S382-A435 PolarHBondContact OG-N 2.69Å; S382-A435 VanDerWaalsContact OG-N 3.12Å; F431-A435 WeakPolarHBondContact O-CB 2.98Å; F431-A435 PolarHBondContact O-N 2.88Å; I432-A435 PolarHBondContact O-N 2.98Å; A435-G439 PolarHBondContact O-N 3.26Å; A435-G439 VanDerWaalsContact O-N 3.14Å
436	F	95.1	Very high	92.3	Very high	37 Å²	37	21 Å²	21	16%	0.162	11%	0.105	C	C	.	.	H	α-helix	trans	-76.9	-37.6	-177.7	-80.1	-79	0	0	0	113.3	I393 C406 I409 I432 A433 R434 G439 G440	I393-F436 HydrophobicContact CD1-CE1 4.31Å; C406-F436 HydrophobicContact CB-CB 4.49Å; C406-F436 VanDerWaalsContact CB-O 3.29Å; C406-F436 WeakPolarHBondContact CB-O 3.18Å; I409-F436 HydrophobicContact CB-CB 4.4Å; I409-F436 HydrophobicContact CB-CD1 4.38Å; I409-F436 HydrophobicContact CB-CD2 4.22Å; I409-F436 HydrophobicContact CB-CG 4.07Å; I409-F436 HydrophobicContact CD1-CD1 3.67Å; I409-F436 HydrophobicContact CD1-CD2 4.26Å; I409-F436 HydrophobicContact CD1-CE1 3.36Å; I409-F436 HydrophobicContact CD1-CE2 4.01Å; I409-F436 HydrophobicContact CD1-CG 4.11Å; I409-F436 HydrophobicContact CD1-CZ 3.55Å; I409-F436 HydrophobicContact CG2-CB 4.28Å; I409-F436 HydrophobicContact CG2-CD1 4.45Å; I409-F436 HydrophobicContact CG2-CD2 3.44Å; I409-F436 VanDerWaalsContact CG2-CD2 3.44Å; I409-F436 HydrophobicContact CG2-CE2 3.83Å; I409-F436 HydrophobicContact CG2-CG 3.8Å; I409-F436 HydrophobicContact CG2-CZ 4.48Å; I432-F436 HydrophobicContact CG2-CD2 3.77Å; I432-F436 HydrophobicContact CG2-CE2 3.91Å; I432-F436 WeakPolarHBondContact O-CD2 3.23Å; I432-F436 PolarHBondContact O-N 3.13Å; I432-F436 VanDerWaalsContact O-N 3.12Å; A433-F436 PolarHBondContact O-N 2.99Å; R434-F436 PolarHBondContact O-N 2.94Å; F436-G439 PolarHBondContact O-N 3.27Å; F436-G440 PolarHBondContact O-N 2.91Å
437	I	95.3	Very high	92.2	Very high	0 Å²	0	20.2 Å²	20.2	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-69.6	-35.6	178.4	-162.7	59.1	0	0	0	111.7	Y331 L334 F407 F410 A433 G439 G440 F441	Y331-I437 HydrophobicContact CD2-CG2 4.15Å; L334-I437 HydrophobicContact CD2-CG2 4.23Å; F407-I437 HydrophobicContact CD1-CD1 3.97Å; F407-I437 HydrophobicContact CE1-CD1 3.83Å; F410-I437 HydrophobicContact CD2-CB 3.68Å; F410-I437 HydrophobicContact CD2-CD1 4.42Å; F410-I437 HydrophobicContact CD2-CG1 4.1Å; F410-I437 HydrophobicContact CD2-CG2 4.07Å; F410-I437 HydrophobicContact CE2-CB 4.18Å; F410-I437 HydrophobicContact CE2-CG1 4.31Å; F410-I437 HydrophobicContact CE2-CG2 4.23Å; F410-I437 HydrophobicContact CG-CB 4.32Å; F410-I437 HydrophobicContact CG-CD1 4.36Å; A433-I437 WeakPolarHBondContact O-CB 2.9Å; A433-I437 VanDerWaalsContact O-CG2 3.28Å; A433-I437 WeakPolarHBondContact O-CG2 3.43Å; A433-I437 PolarHBondContact O-N 3.37Å; I437-G439 VanDerWaalsContact C-N 3.35Å; I437-G440 PolarHBondContact O-N 3.41Å; I437-F441 PolarHBondContact O-N 3.01Å
438	S	92.5	Very high	92.1	Very high	11 Å²	11	19.6 Å²	19.6	8%	0.077	10%	0.097	C	C	.	.	H	α-helix	trans	-60.9	-43.9	169.5	-175	0	0	0	0	111.4	R434 G440 F441 Q442	R434-S438 VanDerWaalsContact O-CB 3.27Å; R434-S438 WeakPolarHBondContact O-CB 3.36Å; R434-S438 PolarHBondContact O-N 2.97Å; S438-G440 PolarHBondContact O-N 3.29Å; S438-F441 VanDerWaalsContact O-CB 3.28Å; S438-F441 WeakPolarHBondContact O-CB 3.44Å; S438-F441 PolarHBondContact O-N 2.87Å; S438-Q442 PolarHBondContact O-N 3.25Å; S438-Q442 VanDerWaalsContact O-N 3.17Å
439	G	90.8	Very high	91.5	Very high	0 Å²	0	16.2 Å²	16.2	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-59.9	-43	173.2	0	0	0	0	0	113.7	T390 A435 F436 I437 F441 Q442 A443	T390-G439 WeakPolarHBondContact CG2-O 3.17Å; T390-G439 VanDerWaalsContact OG1-CA 3.25Å; T390-G439 WeakPolarHBondContact OG1-CA 3.24Å; A435-G439 PolarHBondContact O-N 3.26Å; A435-G439 VanDerWaalsContact O-N 3.14Å; F436-G439 PolarHBondContact O-N 3.27Å; I437-G439 VanDerWaalsContact C-N 3.35Å; G439-F441 VanDerWaalsContact C-N 3.26Å; G439-F441 PolarHBondContact O-N 3.48Å; G439-Q442 PolarHBondContact O-N 2.87Å; G439-A443 PolarHBondContact O-N 3.39Å
440	G	92.1	Very high	91	Very high	0 Å²	0	17.5 Å²	17.5	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-59.2	-37.8	175.3	0	0	0	0	0	112.7	N327 F436 I437 S438 A444	N327-G440 PolarHBondContact ND2-O 3.31Å; F436-G440 PolarHBondContact O-N 2.91Å; I437-G440 PolarHBondContact O-N 3.41Å; S438-G440 PolarHBondContact O-N 3.29Å; G440-A444 PolarHBondContact O-N 3.43Å; G440-A444 VanDerWaalsContact O-N 3.16Å
441	F	90.9	Very high	90.7	Very high	28 Å²	28	17.6 Å²	17.6	12%	0.123	9%	0.087	C	C	.	.	H	α-helix	trans	-60.1	-52.4	173	-150.4	-99.5	0	0	0	110.6	N327 A328 I437 S438 G439 A443 A444 Y445	N327-F441 HydrophobicContact CB-CD2 3.77Å; N327-F441 HydrophobicContact CB-CE2 4.26Å; A328-F441 HydrophobicContact CB-CE2 4.09Å; I437-F441 PolarHBondContact O-N 3.01Å; S438-F441 VanDerWaalsContact O-CB 3.28Å; S438-F441 WeakPolarHBondContact O-CB 3.44Å; S438-F441 PolarHBondContact O-N 2.87Å; G439-F441 VanDerWaalsContact C-N 3.26Å; G439-F441 PolarHBondContact O-N 3.48Å; F441-A443 PolarHBondContact O-N 3.03Å; F441-A444 WeakPolarHBondContact O-CB 3.4Å; F441-A444 PolarHBondContact O-N 3.48Å; F441-A444 VanDerWaalsContact O-N 3.11Å; F441-Y445 AromaticContact CD1-CD2 3.82Å; F441-Y445 HydrophobicContact CD1-CD2 3.82Å; F441-Y445 AromaticContact CD1-CE2 3.41Å; F441-Y445 HydrophobicContact CD1-CE2 3.41Å; F441-Y445 VanDerWaalsContact CD1-CE2 3.41Å; F441-Y445 HydrophobicContact CE1-CD2 4.01Å; F441-Y445 AromaticContact CE1-CE2 3.12Å; F441-Y445 HydrophobicContact CE1-CE2 3.12Å; F441-Y445 AromaticContact CE1-CZ 3.84Å; F441-Y445 HydrophobicContact CG-CE2 4.4Å; F441-Y445 AromaticContact CZ-CE2 3.85Å; F441-Y445 HydrophobicContact CZ-CE2 3.85Å; F441-Y445 WeakPolarHBondContact O-CD2 3.44Å; F441-Y445 PolarHBondContact O-N 3.45Å; F441-Y445 VanDerWaalsContact O-N 3.12Å
442	Q	87.6	Confident	90.2	Very high	11 Å²	11	14.9 Å²	14.9	5%	0.051	8%	0.075	C	C	.	.	H	α-helix	trans	-61.6	-41.8	179.9	-67.2	-178.4	-14.7	0	0	113.2	S438 G439 A444 Y445 V446	S438-Q442 PolarHBondContact O-N 3.25Å; S438-Q442 VanDerWaalsContact O-N 3.17Å; G439-Q442 PolarHBondContact O-N 2.87Å; Q442-A444 VanDerWaalsContact C-N 3.25Å; Q442-A444 PolarHBondContact O-N 3.19Å; Q442-Y445 WeakPolarHBondContact O-CB 3.42Å; Q442-Y445 PolarHBondContact O-N 3.45Å; Q442-Y445 VanDerWaalsContact O-N 3.15Å; Q442-V446 PolarHBondContact O-N 3.46Å; Q442-V446 VanDerWaalsContact O-N 3.08Å
443	A	89.4	Confident	89.4	Confident	0 Å²	0	12.6 Å²	12.6	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-61.1	-36	176.6	0	0	0	0	0	111.8	I394 T402 M403 G439 F441 V446 Y447	I394-A443 HydrophobicContact CD1-CB 3.92Å; T402-A443 HydrophobicContact CG2-CB 4.47Å; M403-A443 HydrophobicContact CG-CB 3.55Å; G439-A443 PolarHBondContact O-N 3.39Å; F441-A443 PolarHBondContact O-N 3.03Å; A443-V446 PolarHBondContact O-N 3.49Å; A443-Y447 VanDerWaalsContact O-CB 3.25Å; A443-Y447 WeakPolarHBondContact O-CB 3.45Å; A443-Y447 PolarHBondContact O-N 3.33Å
444	A	90.9	Very high	88.5	Confident	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-68.1	-37.8	174.6	0	0	0	0	0	112.6	W324 M403 G440 F441 Q442 V446 Y447 T448	W324-A444 HydrophobicContact CZ2-CB 4.41Å; M403-A444 HydrophobicContact SD-CB 4.17Å; G440-A444 PolarHBondContact O-N 3.43Å; G440-A444 VanDerWaalsContact O-N 3.16Å; F441-A444 WeakPolarHBondContact O-CB 3.4Å; F441-A444 PolarHBondContact O-N 3.48Å; F441-A444 VanDerWaalsContact O-N 3.11Å; Q442-A444 VanDerWaalsContact C-N 3.25Å; Q442-A444 PolarHBondContact O-N 3.19Å; A444-V446 VanDerWaalsContact C-N 3.3Å; A444-V446 PolarHBondContact O-N 3.18Å; A444-Y447 PolarHBondContact O-N 2.92Å; A444-T448 WeakPolarHBondContact O-CB 3.18Å; A444-T448 PolarHBondContact O-N 3.46Å; A444-T448 PolarHBondContact O-OG1 3.48Å
445	Y	86.5	Confident	87.6	Confident	55 Å²	55	16.8 Å²	16.8	22%	0.216	9%	0.092	C	C	.	.	H	α-helix	trans	-63.8	-32.7	174.1	-90.4	-96	0	0	0	113.2	W324 F441 Q442 P449 L461	W324-Y445 HydrophobicContact CE3-CE2 4.31Å; W324-Y445 AromaticContact CH2-CD1 3.81Å; W324-Y445 HydrophobicContact CH2-CD1 3.81Å; W324-Y445 AromaticContact CH2-CD2 3.37Å; W324-Y445 HydrophobicContact CH2-CD2 3.37Å; W324-Y445 AromaticContact CH2-CE1 3.66Å; W324-Y445 HydrophobicContact CH2-CE1 3.66Å; W324-Y445 AromaticContact CH2-CE2 3.11Å; W324-Y445 HydrophobicContact CH2-CE2 3.11Å; W324-Y445 AromaticContact CH2-CG 3.71Å; W324-Y445 HydrophobicContact CH2-CG 3.71Å; W324-Y445 AromaticContact CH2-CZ 3.33Å; W324-Y445 HydrophobicContact CZ2-CD2 4.05Å; W324-Y445 HydrophobicContact CZ2-CE2 4.18Å; W324-Y445 HydrophobicContact CZ2-CG 4.25Å; W324-Y445 AromaticContact CZ3-CD2 3.88Å; W324-Y445 HydrophobicContact CZ3-CD2 3.88Å; W324-Y445 HydrophobicContact CZ3-CE1 4.2Å; W324-Y445 AromaticContact CZ3-CE2 3.18Å; W324-Y445 HydrophobicContact CZ3-CE2 3.18Å; W324-Y445 AromaticContact CZ3-CZ 3.43Å; W324-Y445 VanDerWaalsContact CZ3-CZ 3.43Å; F441-Y445 AromaticContact CD1-CD2 3.82Å; F441-Y445 HydrophobicContact CD1-CD2 3.82Å; F441-Y445 AromaticContact CD1-CE2 3.41Å; F441-Y445 HydrophobicContact CD1-CE2 3.41Å; F441-Y445 VanDerWaalsContact CD1-CE2 3.41Å; F441-Y445 HydrophobicContact CE1-CD2 4.01Å; F441-Y445 AromaticContact CE1-CE2 3.12Å; F441-Y445 HydrophobicContact CE1-CE2 3.12Å; F441-Y445 AromaticContact CE1-CZ 3.84Å; F441-Y445 HydrophobicContact CG-CE2 4.4Å; F441-Y445 AromaticContact CZ-CE2 3.85Å; F441-Y445 HydrophobicContact CZ-CE2 3.85Å; F441-Y445 WeakPolarHBondContact O-CD2 3.44Å; F441-Y445 PolarHBondContact O-N 3.45Å; F441-Y445 VanDerWaalsContact O-N 3.12Å; Q442-Y445 WeakPolarHBondContact O-CB 3.42Å; Q442-Y445 PolarHBondContact O-N 3.45Å; Q442-Y445 VanDerWaalsContact O-N 3.15Å; Y445-P449 WeakPolarHBondContact O-CD 3.28Å; Y445-P449 WeakPolarHBondContact O-CG 3.43Å; Y445-L461 HydrophobicContact CD1-CD1 4.5Å
446	V	84.2	Confident	86.9	Confident	32 Å²	32	16.5 Å²	16.5	19%	0.194	9%	0.09	C	C	.	.	H	α-helix	trans	-78.9	-46.3	175.8	175.4	0	0	0	0	111	L211 I394 R399 Q442 A443 A444 P449 E450	L211-V446 HydrophobicContact CD2-CG2 4.23Å; I394-V446 HydrophobicContact CD1-CB 4.48Å; R399-V446 HydrophobicContact CG-CG1 4.46Å; Q442-V446 PolarHBondContact O-N 3.46Å; Q442-V446 VanDerWaalsContact O-N 3.08Å; A443-V446 PolarHBondContact O-N 3.49Å; A444-V446 VanDerWaalsContact C-N 3.3Å; A444-V446 PolarHBondContact O-N 3.18Å; V446-P449 VanDerWaalsContact O-CD 3.31Å; V446-P449 WeakPolarHBondContact O-CD 3.35Å; V446-P449 WeakPolarHBondContact O-CG 3.28Å; V446-E450 WeakPolarHBondContact CG1-OE1 3.06Å; V446-E450 VanDerWaalsContact O-CG 3.31Å; V446-E450 WeakPolarHBondContact O-CG 3.06Å
447	Y	88.6	Confident	86.3	Confident	0 Å²	0	17 Å²	17	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-66.8	-41.8	-174.9	-178.4	-96.8	0	0	0	113.2	L320 R399 M403 A443 A444 E450 V451 L508 I510 T512	L320-Y447 HydrophobicContact CD1-CE1 4.43Å; L320-Y447 HydrophobicContact CD2-CD1 3.73Å; L320-Y447 HydrophobicContact CD2-CE1 3.82Å; L320-Y447 HydrophobicContact CG-CE1 4.5Å; R399-Y447 HydrophobicContact CB-CD2 3.64Å; R399-Y447 HydrophobicContact CB-CG 4.38Å; R399-Y447 HydrophobicContact CG-CD2 4.4Å; M403-Y447 HydrophobicContact CE-CD1 3.82Å; M403-Y447 HydrophobicContact CE-CD2 4Å; M403-Y447 HydrophobicContact CE-CE1 4.27Å; M403-Y447 HydrophobicContact CE-CE2 4.43Å; M403-Y447 HydrophobicContact CE-CG 3.65Å; A443-Y447 VanDerWaalsContact O-CB 3.25Å; A443-Y447 WeakPolarHBondContact O-CB 3.45Å; A443-Y447 PolarHBondContact O-N 3.33Å; A444-Y447 PolarHBondContact O-N 2.92Å; Y447-E450 PolarHBondContact O-N 2.64Å; Y447-V451 HydrophobicContact CD1-CG2 3.86Å; Y447-V451 HydrophobicContact CD2-CG2 4.17Å; Y447-V451 HydrophobicContact CE1-CB 4.47Å; Y447-V451 HydrophobicContact CE1-CG2 3.39Å; Y447-V451 HydrophobicContact CE2-CG2 3.76Å; Y447-V451 HydrophobicContact CG-CG2 4.24Å; Y447-V451 WeakPolarHBondContact O-CG2 3.37Å; Y447-V451 PolarHBondContact O-N 2.85Å; Y447-V451 VanDerWaalsContact O-N 3.13Å; Y447-L508 HydrophobicContact CD1-CD1 4.33Å; Y447-L508 HydrophobicContact CE1-CD1 3.62Å; Y447-L508 HydrophobicContact CE1-CD2 4.05Å; Y447-L508 HydrophobicContact CE1-CG 4.35Å; Y447-I510 WeakPolarHBondContact CE2-O 3.16Å; Y447-I510 PolarHBondContact OH-O 3.35Å; Y447-T512 HydrophobicContact CD2-CG2 3.9Å; Y447-T512 HydrophobicContact CE2-CG2 3.76Å
448	T	89.2	Confident	85.5	Confident	0 Å²	0	21 Å²	21	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-57	-52	-175.5	-54.1	0	0	0	0	113.1	L320 W324 A444 E450 V451 Y452 L461 C464	L320-T448 HydrophobicContact CD1-CG2 4.48Å; W324-T448 PolarHBondContact NE1-OG1 2.84Å; A444-T448 WeakPolarHBondContact O-CB 3.18Å; A444-T448 PolarHBondContact O-N 3.46Å; A444-T448 PolarHBondContact O-OG1 3.48Å; T448-E450 VanDerWaalsContact C-N 3.31Å; T448-E450 PolarHBondContact O-N 3.45Å; T448-V451 PolarHBondContact O-N 3.12Å; T448-Y452 HydrophobicContact CG2-CD2 4.18Å; T448-Y452 HydrophobicContact CG2-CE2 4.08Å; T448-Y452 VanDerWaalsContact O-CD2 3.29Å; T448-Y452 WeakPolarHBondContact O-CD2 3.13Å; T448-L461 HydrophobicContact CG2-CB 4.21Å; T448-L461 HydrophobicContact CG2-CD1 3.99Å; T448-C464 HydrophobicContact CG2-CB 4.44Å
449	P	82.3	Confident	85.1	Confident	28 Å²	28	23 Å²	23	18%	0.182	13%	0.133	C	C	.	.	H	α-helix	trans	-70.3	-24	177.9	27.6	-35.2	0	0	0	114.1	Y445 V446 V451 R457	Y445-P449 WeakPolarHBondContact O-CD 3.28Å; Y445-P449 WeakPolarHBondContact O-CG 3.43Å; V446-P449 VanDerWaalsContact O-CD 3.31Å; V446-P449 WeakPolarHBondContact O-CD 3.35Å; V446-P449 WeakPolarHBondContact O-CG 3.28Å; P449-V451 VanDerWaalsContact C-N 3.33Å; P449-R457 HydrophobicContact CB-CG 3.7Å; P449-R457 WeakPolarHBondContact O-CD 3.35Å; P449-R457 PolarHBondContact O-NE 3.22Å
450	E	83.8	Confident	84.9	Confident	43 Å²	43	23 Å²	23	20%	0.201	13%	0.133	C	C	.	.	H	α-helix	trans	-72.7	-24.9	176	-73.1	177.5	171.2	0	0	112.5	R399 V446 Y447 T448 T512	R399-E450 IonicContact NE-OE1 3.26Å; R399-E450 IonicContact NE-OE2 3.32Å; R399-E450 PolarHBondContact NE-OE2 3.26Å; R399-E450 IonicContact NH2-OE1 2.84Å; V446-E450 WeakPolarHBondContact CG1-OE1 3.06Å; V446-E450 VanDerWaalsContact O-CG 3.31Å; V446-E450 WeakPolarHBondContact O-CG 3.06Å; Y447-E450 PolarHBondContact O-N 2.64Å; T448-E450 VanDerWaalsContact C-N 3.31Å; T448-E450 PolarHBondContact O-N 3.45Å; E450-T512 HydrophobicContact CB-CG2 3.71Å; E450-T512 WeakPolarHBondContact OE2-CB 3.26Å; E450-T512 PolarHBondContact OE2-OG1 3.25Å
451	V	87.3	Confident	84.6	Confident	3 Å²	3	25.5 Å²	25.5	2%	0.018	15%	0.146	C	C	.	.	H	α-helix	trans	-87.3	-32.5	-177.4	167	0	0	0	0	113.7	T316 Y447 T448 P449 T512	T316-V451 HydrophobicContact CG2-CG1 3.52Å; Y447-V451 HydrophobicContact CD1-CG2 3.86Å; Y447-V451 HydrophobicContact CD2-CG2 4.17Å; Y447-V451 HydrophobicContact CE1-CB 4.47Å; Y447-V451 HydrophobicContact CE1-CG2 3.39Å; Y447-V451 HydrophobicContact CE2-CG2 3.76Å; Y447-V451 HydrophobicContact CG-CG2 4.24Å; Y447-V451 WeakPolarHBondContact O-CG2 3.37Å; Y447-V451 PolarHBondContact O-N 2.85Å; Y447-V451 VanDerWaalsContact O-N 3.13Å; T448-V451 PolarHBondContact O-N 3.12Å; P449-V451 VanDerWaalsContact C-N 3.33Å; V451-T512 HydrophobicContact CG2-CG2 3.63Å
452	Y	85.2	Confident	84.4	Confident	2 Å²	2	26.3 Å²	26.3	1%	0.008	16%	0.163	C	C	.	.	S	Bend	trans	-93	140.2	-178	-70.4	-70.6	0	0	0	111.6	L308 F313 T317 L320 T448	L308-Y452 HydrophobicContact CD2-CD1 3.99Å; L308-Y452 HydrophobicContact CD2-CE1 3.45Å; L308-Y452 VanDerWaalsContact CD2-CE1 3.45Å; F313-Y452 HydrophobicContact CB-CE1 4.5Å; F313-Y452 HydrophobicContact CD1-CD1 4.33Å; F313-Y452 HydrophobicContact CD1-CE1 4.27Å; F313-Y452 HydrophobicContact CG-CE1 4.49Å; T317-Y452 VanDerWaalsContact CA-OH 3.24Å; T317-Y452 WeakPolarHBondContact CA-OH 3.38Å; T317-Y452 WeakPolarHBondContact CB-OH 3.46Å; T317-Y452 PolarHBondContact OG1-OH 3.12Å; L320-Y452 HydrophobicContact CD1-CE2 3.85Å; T448-Y452 HydrophobicContact CG2-CD2 4.18Å; T448-Y452 HydrophobicContact CG2-CE2 4.08Å; T448-Y452 VanDerWaalsContact O-CD2 3.29Å; T448-Y452 WeakPolarHBondContact O-CD2 3.13Å
453	P	80.7	Confident	84.5	Confident	4 Å²	4	26.8 Å²	26.8	3%	0.026	17%	0.166	C	C	.	.			trans	-65.8	158.7	174.8	28.9	-34.9	0	0	0	110.8	F313 A455 T456 R457	F313-P453 HydrophobicContact CZ-CG 4.12Å; P453-A455 VanDerWaalsContact C-N 3.26Å; P453-A455 PolarHBondContact O-N 2.83Å; P453-A455 VanDerWaalsContact O-N 3.11Å; P453-T456 VanDerWaalsContact CD-OG1 3.3Å; P453-T456 WeakPolarHBondContact CD-OG1 3.14Å; P453-T456 VanDerWaalsContact CG-OG1 3.32Å; P453-T456 WeakPolarHBondContact CG-OG1 3.48Å; P453-T456 PolarHBondContact O-N 2.68Å; P453-R457 WeakPolarHBondContact O-CB 3.24Å; P453-R457 PolarHBondContact O-N 2.9Å
454	T	75.9	Confident	84.6	Confident	62 Å²	62	26.8 Å²	26.8	38%	0.38	17%	0.166	S	C	.	.	H	α-helix	trans	-50.7	-41.8	-172.3	-58.7	0	0	0	0	113.6	T456 R457 Q518	T454-T456 PolarHBondContact O-N 3.25Å; T454-R457 PolarHBondContact OG1-NH2 3.02Å; T454-Q518 PolarHBondContact OG1-O 3.06Å; T454-Q518 VanDerWaalsContact OG1-O 3.12Å
455	A	75.8	Confident	84.5	Confident	29 Å²	29	28.2 Å²	28.2	24%	0.24	18%	0.176	C	C	.	.	H	α-helix	trans	-64.3	-30.5	179.5	0	0	0	0	0	115.1	G303 P453	G303-A455 PolarHBondContact N-O 3.18Å; P453-A455 VanDerWaalsContact C-N 3.26Å; P453-A455 PolarHBondContact O-N 2.83Å; P453-A455 VanDerWaalsContact O-N 3.11Å
456	T	81.2	Confident	84.7	Confident	1 Å²	1	27.2 Å²	27.2	1%	0.006	18%	0.182	C	C	.	.	H	α-helix	trans	-111.7	-5	-178.9	56.8	0	0	0	0	113.4	D307 P453 T454 A458 L459 G460	D307-T456 HydrophobicContact CB-CG2 4.08Å; P453-T456 VanDerWaalsContact CD-OG1 3.3Å; P453-T456 WeakPolarHBondContact CD-OG1 3.14Å; P453-T456 VanDerWaalsContact CG-OG1 3.32Å; P453-T456 WeakPolarHBondContact CG-OG1 3.48Å; P453-T456 PolarHBondContact O-N 2.68Å; T454-T456 PolarHBondContact O-N 3.25Å; T456-A458 PolarHBondContact O-N 3.18Å; T456-L459 WeakPolarHBondContact O-CB 3.5Å; T456-L459 PolarHBondContact O-N 3.46Å; T456-L459 VanDerWaalsContact O-N 3.08Å; T456-G460 PolarHBondContact O-N 3.09Å
457	R	82.1	Confident	85.1	Confident	48 Å²	48	28.2 Å²	28.2	18%	0.181	19%	0.186	C	C	.	.	H	α-helix	trans	-52.9	-51.8	-177	-174.8	179.9	-71	143.4	10.7	113.6	P449 P453 T454 L459 G460 L461 Q518	P449-R457 HydrophobicContact CB-CG 3.7Å; P449-R457 WeakPolarHBondContact O-CD 3.35Å; P449-R457 PolarHBondContact O-NE 3.22Å; P453-R457 WeakPolarHBondContact O-CB 3.24Å; P453-R457 PolarHBondContact O-N 2.9Å; T454-R457 PolarHBondContact OG1-NH2 3.02Å; R457-L459 VanDerWaalsContact C-N 3.28Å; R457-L459 PolarHBondContact O-N 2.74Å; R457-G460 PolarHBondContact O-N 3.42Å; R457-L461 PolarHBondContact O-N 2.98Å; R457-Q518 PolarHBondContact NH2-O 2.81Å
458	A	77.8	Confident	85.4	Confident	84 Å²	84	28.4 Å²	28.4	69%	0.694	19%	0.187	S	C	*	.	H	α-helix	trans	-63.7	-36.4	179.7	0	0	0	0	0	111.9	T456 G462	T456-A458 PolarHBondContact O-N 3.18Å; A458-G462 PolarHBondContact O-N 2.9Å
459	L	84.5	Confident	85.5	Confident	54 Å²	54	29.4 Å²	29.4	28%	0.283	19%	0.191	S	C	.	.	H	α-helix	trans	-71.8	-40.7	178.6	-167.3	69.9	0	0	0	112.1	G303 K304 M305 L308 T456 R457 G462 T463	G303-L459 WeakPolarHBondContact O-CD2 3.45Å; K304-L459 WeakPolarHBondContact O-CD2 3.48Å; M305-L459 HydrophobicContact CB-CD2 4.39Å; L308-L459 HydrophobicContact CD1-CD2 3.84Å; L308-L459 HydrophobicContact CD1-CG 3.77Å; L308-L459 HydrophobicContact CG-CD2 4.16Å; L308-L459 HydrophobicContact CG-CG 4.47Å; T456-L459 WeakPolarHBondContact O-CB 3.5Å; T456-L459 PolarHBondContact O-N 3.46Å; T456-L459 VanDerWaalsContact O-N 3.08Å; R457-L459 VanDerWaalsContact C-N 3.28Å; R457-L459 PolarHBondContact O-N 2.74Å; L459-G462 PolarHBondContact O-N 2.81Å; L459-T463 WeakPolarHBondContact O-CG2 3.25Å; L459-T463 PolarHBondContact O-N 2.74Å; L459-T463 PolarHBondContact O-OG1 3.41Å
460	G	86.4	Confident	86.1	Confident	0 Å²	0	30.4 Å²	30.4	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-59.8	-51.4	174.3	0	0	0	0	0	111.5	T456 R457 G462 T463 C464	T456-G460 PolarHBondContact O-N 3.09Å; R457-G460 PolarHBondContact O-N 3.42Å; G460-G462 PolarHBondContact O-N 3.07Å; G460-T463 PolarHBondContact O-N 2.94Å; G460-T463 PolarHBondContact O-OG1 3.41Å; G460-T463 VanDerWaalsContact O-OG1 3.1Å; G460-C464 WeakPolarHBondContact O-CB 3.32Å; G460-C464 PolarHBondContact O-N 3.39Å; G460-C464 PolarHBondContact O-SG 2.84Å
461	L	86.6	Confident	86.7	Confident	52 Å²	52	28.3 Å²	28.3	27%	0.272	19%	0.187	S	C	.	.	H	α-helix	trans	-62	-42.9	176.4	-174.3	64.9	0	0	0	112.3	W324 Y445 T448 R457 C464 S465	W324-L461 HydrophobicContact CH2-CD1 3.65Å; W324-L461 HydrophobicContact CZ2-CD1 3.48Å; W324-L461 VanDerWaalsContact CZ2-CD1 3.48Å; Y445-L461 HydrophobicContact CD1-CD1 4.5Å; T448-L461 HydrophobicContact CG2-CB 4.21Å; T448-L461 HydrophobicContact CG2-CD1 3.99Å; R457-L461 PolarHBondContact O-N 2.98Å; L461-C464 PolarHBondContact O-N 3.14Å; L461-S465 VanDerWaalsContact O-CB 3.32Å; L461-S465 WeakPolarHBondContact O-CB 3.4Å; L461-S465 PolarHBondContact O-N 2.6Å
462	G	86.1	Confident	87	Confident	45 Å²	45	28.2 Å²	28.2	46%	0.464	19%	0.186	S	C	.	.	H	α-helix	trans	-63.1	-44.5	179.5	0	0	0	0	0	113.4	A458 L459 G460 S465 G466	A458-G462 PolarHBondContact O-N 2.9Å; L459-G462 PolarHBondContact O-N 2.81Å; G460-G462 PolarHBondContact O-N 3.07Å; G462-S465 PolarHBondContact O-N 3.28Å; G462-G466 PolarHBondContact O-N 2.69Å
463	T	89.8	Confident	87.4	Confident	20 Å²	20	30.1 Å²	30.1	12%	0.123	20%	0.196	C	C	.	.	H	α-helix	trans	-69	-38.9	178	56.5	0	0	0	0	112.4	M305 L308 W321 L459 G460 G466 M467	M305-T463 HydrophobicContact CE-CG2 3.62Å; M305-T463 HydrophobicContact SD-CG2 4.21Å; L308-T463 HydrophobicContact CD1-CG2 3.87Å; W321-T463 HydrophobicContact CZ2-CG2 4.41Å; W321-T463 PolarHBondContact NE1-OG1 3.37Å; L459-T463 WeakPolarHBondContact O-CG2 3.25Å; L459-T463 PolarHBondContact O-N 2.74Å; L459-T463 PolarHBondContact O-OG1 3.41Å; G460-T463 PolarHBondContact O-N 2.94Å; G460-T463 PolarHBondContact O-OG1 3.41Å; G460-T463 VanDerWaalsContact O-OG1 3.1Å; T463-G466 PolarHBondContact O-N 2.99Å; T463-M467 PolarHBondContact O-N 3.45Å
464	C	92.2	Very high	88.2	Confident	0 Å²	0	33.3 Å²	33.3	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-62.1	-45.6	173.2	-68.4	0	0	0	0	111.6	W324 T448 G460 L461 G466 M467 A468	W324-C464 HydrophobicContact CB-CB 4.29Å; W324-C464 WeakPolarHBondContact CB-O 3.44Å; W324-C464 HydrophobicContact CD2-CB 3.83Å; W324-C464 HydrophobicContact CG-CB 3.65Å; T448-C464 HydrophobicContact CG2-CB 4.44Å; G460-C464 WeakPolarHBondContact O-CB 3.32Å; G460-C464 PolarHBondContact O-N 3.39Å; G460-C464 PolarHBondContact O-SG 2.84Å; L461-C464 PolarHBondContact O-N 3.14Å; C464-G466 VanDerWaalsContact C-N 3.33Å; C464-G466 PolarHBondContact O-N 3.46Å; C464-M467 PolarHBondContact O-N 3.19Å; C464-M467 VanDerWaalsContact O-N 3.17Å; C464-A468 PolarHBondContact O-N 3.19Å
465	S	89.1	Confident	89.1	Confident	31 Å²	31	30.3 Å²	30.3	22%	0.217	19%	0.194	C	C	.	.	H	α-helix	trans	-61	-41.3	175.4	-172	0	0	0	0	111.9	L461 G462 M467 A468 R469	L461-S465 VanDerWaalsContact O-CB 3.32Å; L461-S465 WeakPolarHBondContact O-CB 3.4Å; L461-S465 PolarHBondContact O-N 2.6Å; G462-S465 PolarHBondContact O-N 3.28Å; S465-M467 VanDerWaalsContact C-N 3.32Å; S465-M467 PolarHBondContact O-N 2.94Å; S465-A468 WeakPolarHBondContact O-CA 3.26Å; S465-A468 WeakPolarHBondContact O-CB 3.22Å; S465-A468 PolarHBondContact O-N 3.45Å; S465-A468 VanDerWaalsContact O-N 3.13Å; S465-R469 WeakPolarHBondContact O-CG 3.42Å; S465-R469 PolarHBondContact O-N 3.31Å
466	G	90.2	Very high	90	Very high	33 Å²	33	29 Å²	29	34%	0.34	18%	0.183	S	C	.	.	H	α-helix	trans	-57	-43.8	173.1	0	0	0	0	0	112.6	G462 T463 C464 A468 R469 V470	G462-G466 PolarHBondContact O-N 2.69Å; T463-G466 PolarHBondContact O-N 2.99Å; C464-G466 VanDerWaalsContact C-N 3.33Å; C464-G466 PolarHBondContact O-N 3.46Å; G466-A468 VanDerWaalsContact C-N 3.34Å; G466-A468 PolarHBondContact O-N 3.48Å; G466-R469 WeakPolarHBondContact O-CB 3.41Å; G466-R469 PolarHBondContact O-N 2.9Å; G466-R469 VanDerWaalsContact O-N 3.16Å; G466-V470 PolarHBondContact O-N 3.37Å
467	M	93.2	Very high	90.6	Very high	53 Å²	53	33 Å²	33	26%	0.261	20%	0.2	S	C	.	.	H	α-helix	trans	-67.3	-34	176	-165.6	60.5	62.9	0	0	112.8	W321 F325 T463 C464 S465 R469 V470 G471	W321-M467 HydrophobicContact CB-CB 4.33Å; W321-M467 HydrophobicContact CB-CG 4.06Å; W321-M467 HydrophobicContact CD2-CE 4.05Å; W321-M467 HydrophobicContact CE3-CE 3.54Å; W321-M467 HydrophobicContact CG-CB 4.42Å; W321-M467 HydrophobicContact CZ3-CE 3.94Å; W321-M467 VanDerWaalsContact O-CG 3.26Å; W321-M467 WeakPolarHBondContact O-CG 3.25Å; F325-M467 HydrophobicContact CB-CG 3.95Å; F325-M467 HydrophobicContact CD2-CG 4.47Å; F325-M467 HydrophobicContact CD2-SD 4.46Å; T463-M467 PolarHBondContact O-N 3.45Å; C464-M467 PolarHBondContact O-N 3.19Å; C464-M467 VanDerWaalsContact O-N 3.17Å; S465-M467 VanDerWaalsContact C-N 3.32Å; S465-M467 PolarHBondContact O-N 2.94Å; M467-R469 VanDerWaalsContact C-N 3.27Å; M467-R469 PolarHBondContact O-N 2.99Å; M467-V470 WeakPolarHBondContact O-CB 3.12Å; M467-V470 PolarHBondContact O-N 3.16Å; M467-V470 VanDerWaalsContact O-N 3.14Å; M467-V470 HydrophobicContact SD-CB 4.23Å; M467-V470 HydrophobicContact SD-CG2 4.26Å; M467-G471 PolarHBondContact O-N 3.22Å; M467-G471 VanDerWaalsContact O-N 3.15Å
468	A	93.8	Very high	91.1	Very high	4 Å²	4	32.2 Å²	32.2	3%	0.033	20%	0.199	C	C	.	.	H	α-helix	trans	-58.2	-40.5	170.7	0	0	0	0	0	111.5	W324 A328 C464 S465 G466 V470 G471 A472	W324-A468 HydrophobicContact CB-CB 4.19Å; W324-A468 HydrophobicContact CE3-CB 3.76Å; W324-A468 WeakPolarHBondContact O-CB 3.41Å; A328-A468 HydrophobicContact CB-CB 3.69Å; A328-A468 WeakPolarHBondContact CB-O 3.44Å; C464-A468 PolarHBondContact O-N 3.19Å; S465-A468 WeakPolarHBondContact O-CA 3.26Å; S465-A468 WeakPolarHBondContact O-CB 3.22Å; S465-A468 PolarHBondContact O-N 3.45Å; S465-A468 VanDerWaalsContact O-N 3.13Å; G466-A468 VanDerWaalsContact C-N 3.34Å; G466-A468 PolarHBondContact O-N 3.48Å; A468-V470 VanDerWaalsContact C-N 3.3Å; A468-V470 PolarHBondContact O-N 3.32Å; A468-G471 PolarHBondContact O-N 3Å; A468-G471 VanDerWaalsContact O-N 3.17Å; A468-A472 PolarHBondContact O-N 3.44Å
469	R	92.2	Very high	91.7	Very high	21 Å²	21	28.2 Å²	28.2	8%	0.079	17%	0.166	C	C	.	.	H	α-helix	trans	-65.3	-32.3	176.2	-59.5	-61.3	171.7	-168.9	-3.5	112.7	M133 M134 Y332 S465 G466 M467 A472 L473	M133-R469 PolarHBondContact SD-NH1 3.22Å; M134-R469 HydrophobicContact CB-CB 4.35Å; M134-R469 HydrophobicContact CG-CB 4.42Å; Y332-R469 PolarHBondContact OH-NH1 3.43Å; S465-R469 WeakPolarHBondContact O-CG 3.42Å; S465-R469 PolarHBondContact O-N 3.31Å; G466-R469 WeakPolarHBondContact O-CB 3.41Å; G466-R469 PolarHBondContact O-N 2.9Å; G466-R469 VanDerWaalsContact O-N 3.16Å; M467-R469 VanDerWaalsContact C-N 3.27Å; M467-R469 PolarHBondContact O-N 2.99Å; R469-A472 PolarHBondContact O-N 3.47Å; R469-L473 WeakPolarHBondContact O-CB 3.31Å; R469-L473 PolarHBondContact O-N 3.4Å
470	V	94.6	Very high	91.8	Very high	49 Å²	49	25.8 Å²	25.8	30%	0.297	15%	0.154	S	C	.	.	H	α-helix	trans	-64.3	-43.3	172.1	-177.3	0	0	0	0	110.7	M134 F325 G466 M467 A468 A472 L473 I474	M134-V470 HydrophobicContact SD-CG2 4.24Å; F325-V470 HydrophobicContact CD2-CB 4.44Å; F325-V470 HydrophobicContact CD2-CG1 4.49Å; F325-V470 HydrophobicContact CE2-CG1 4.17Å; G466-V470 PolarHBondContact O-N 3.37Å; M467-V470 WeakPolarHBondContact O-CB 3.12Å; M467-V470 PolarHBondContact O-N 3.16Å; M467-V470 VanDerWaalsContact O-N 3.14Å; M467-V470 HydrophobicContact SD-CB 4.23Å; M467-V470 HydrophobicContact SD-CG2 4.26Å; A468-V470 VanDerWaalsContact C-N 3.3Å; A468-V470 PolarHBondContact O-N 3.32Å; V470-A472 VanDerWaalsContact C-N 3.35Å; V470-A472 PolarHBondContact O-N 2.97Å; V470-L473 WeakPolarHBondContact O-CB 3Å; V470-L473 PolarHBondContact O-N 3.02Å; V470-I474 HydrophobicContact CG1-CD1 4.12Å; V470-I474 WeakPolarHBondContact O-CG1 3.49Å; V470-I474 PolarHBondContact O-N 3.45Å
471	G	95.3	Very high	92	Very high	0 Å²	0	28 Å²	28	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-59.8	-45.6	173.8	0	0	0	0	0	112.2	F325 F329 M467 A468 L473 I474 T475	F325-G471 VanDerWaalsContact CD2-CA 3.49Å; F329-G471 WeakPolarHBondContact CD2-O 3.29Å; M467-G471 PolarHBondContact O-N 3.22Å; M467-G471 VanDerWaalsContact O-N 3.15Å; A468-G471 PolarHBondContact O-N 3Å; A468-G471 VanDerWaalsContact O-N 3.17Å; G471-L473 VanDerWaalsContact C-N 3.29Å; G471-L473 PolarHBondContact O-N 3.46Å; G471-I474 PolarHBondContact O-N 3.16Å; G471-T475 PolarHBondContact O-N 3.29Å
472	A	94.1	Very high	92	Very high	0 Å²	0	27.3 Å²	27.3	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-64.8	-30.3	176.8	0	0	0	0	0	113.2	F130 A328 Y332 A468 R469 V470 T475 P476	F130-A472 HydrophobicContact CD1-CB 3.5Å; F130-A472 VanDerWaalsContact CD1-CB 3.5Å; F130-A472 HydrophobicContact CD2-CB 4.44Å; F130-A472 WeakPolarHBondContact CD2-O 3.4Å; F130-A472 HydrophobicContact CE1-CB 3.4Å; F130-A472 VanDerWaalsContact CE1-CB 3.4Å; F130-A472 HydrophobicContact CE2-CB 4.36Å; F130-A472 WeakPolarHBondContact CE2-O 3.36Å; F130-A472 HydrophobicContact CG-CB 4.02Å; F130-A472 HydrophobicContact CZ-CB 3.84Å; A328-A472 HydrophobicContact CB-CB 4.42Å; Y332-A472 HydrophobicContact CD2-CB 3.51Å; Y332-A472 HydrophobicContact CE2-CB 3.91Å; Y332-A472 HydrophobicContact CG-CB 4.38Å; A468-A472 PolarHBondContact O-N 3.44Å; R469-A472 PolarHBondContact O-N 3.47Å; V470-A472 VanDerWaalsContact C-N 3.35Å; V470-A472 PolarHBondContact O-N 2.97Å; A472-T475 WeakPolarHBondContact O-CG2 3.35Å; A472-P476 WeakPolarHBondContact O-CD 3.43Å
473	L	95.1	Very high	91.9	Very high	42 Å²	42	25.7 Å²	25.7	22%	0.22	14%	0.143	C	C	.	.	H	α-helix	trans	-70.4	-37.4	176.4	177.8	62.8	0	0	0	112.8	S127 F130 V131 M134 R469 V470 G471 P476	S127-L473 WeakPolarHBondContact O-CD1 3.22Å; S127-L473 PolarHBondContact OG-O 3.19Å; F130-L473 HydrophobicContact CB-CB 4.28Å; F130-L473 HydrophobicContact CB-CD1 4.21Å; V131-L473 HydrophobicContact CG2-CD1 3.31Å; V131-L473 HydrophobicContact CG2-CD2 4.28Å; V131-L473 HydrophobicContact CG2-CG 4.44Å; M134-L473 HydrophobicContact CE-CD2 4.47Å; R469-L473 WeakPolarHBondContact O-CB 3.31Å; R469-L473 PolarHBondContact O-N 3.4Å; V470-L473 WeakPolarHBondContact O-CB 3Å; V470-L473 PolarHBondContact O-N 3.02Å; G471-L473 VanDerWaalsContact C-N 3.29Å; G471-L473 PolarHBondContact O-N 3.46Å; L473-P476 VanDerWaalsContact O-CD 3.29Å; L473-P476 WeakPolarHBondContact O-CD 3.31Å
474	I	95.6	Very high	91.4	Very high	71 Å²	71	27.2 Å²	27.2	36%	0.364	15%	0.149	S	C	.	.	H	α-helix	trans	-79.3	-32.6	-177.7	-64.8	172	0	0	0	111.1	F325 F329 V470 G471 F477 I478	F325-I474 HydrophobicContact CE2-CD1 3.97Å; F325-I474 HydrophobicContact CZ-CD1 4.09Å; F329-I474 HydrophobicContact CE2-CG2 4.17Å; V470-I474 HydrophobicContact CG1-CD1 4.12Å; V470-I474 WeakPolarHBondContact O-CG1 3.49Å; V470-I474 PolarHBondContact O-N 3.45Å; G471-I474 PolarHBondContact O-N 3.16Å; I474-F477 PolarHBondContact O-N 3.22Å; I474-I478 HydrophobicContact CG2-CG1 4.17Å; I474-I478 PolarHBondContact O-N 3.42Å
475	T	95	Very high	90.9	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-53	-39.3	-173.2	-150.1	0	0	0	0	115.3	F329 G333 L336 G471 A472 F477 I478 A479 Y494	F329-T475 PolarHBondContact O-OG1 3.2Å; G333-T475 WeakPolarHBondContact CA-OG1 3.46Å; G333-T475 PolarHBondContact N-OG1 2.94Å; L336-T475 HydrophobicContact CD1-CG2 4.13Å; G471-T475 PolarHBondContact O-N 3.29Å; A472-T475 WeakPolarHBondContact O-CG2 3.35Å; T475-F477 PolarHBondContact O-N 2.83Å; T475-I478 CarbonylContact O-C 3.56Å; T475-I478 PolarHBondContact O-N 3.37Å; T475-I478 VanDerWaalsContact O-N 3.07Å; T475-A479 WeakPolarHBondContact O-CB 3.33Å; T475-A479 PolarHBondContact O-N 3.5Å; T475-Y494 PolarHBondContact O-OH 2.99Å; T475-Y494 PolarHBondContact OG1-OH 3.42Å
476	P	94.6	Very high	90.7	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-70.6	-31.9	-176.6	-16.8	32.5	0	0	0	113.4	A123 T126 S127 F130 L336 A472 L473 I478 Q480	A123-P476 HydrophobicContact CB-CB 4.36Å; T126-P476 WeakPolarHBondContact OG1-CB 3.36Å; T126-P476 WeakPolarHBondContact OG1-CG 3.16Å; S127-P476 WeakPolarHBondContact OG-CG 3.29Å; F130-P476 HydrophobicContact CD2-CG 4.34Å; F130-P476 HydrophobicContact CE2-CG 4.16Å; L336-P476 HydrophobicContact CD1-CB 3.79Å; L336-P476 HydrophobicContact CD1-CG 3.8Å; A472-P476 WeakPolarHBondContact O-CD 3.43Å; L473-P476 VanDerWaalsContact O-CD 3.29Å; L473-P476 WeakPolarHBondContact O-CD 3.31Å; P476-I478 VanDerWaalsContact C-N 3.25Å; P476-I478 PolarHBondContact O-N 2.95Å; P476-Q480 WeakPolarHBondContact O-CA 3.49Å; P476-Q480 WeakPolarHBondContact O-CB 3.36Å; P476-Q480 WeakPolarHBondContact O-CG 3.45Å; P476-Q480 PolarHBondContact O-N 3.28Å
477	F	94.2	Very high	90.3	Very high	87 Å²	87	32.4 Å²	32.4	38%	0.382	18%	0.179	S	C	.	.	I	π-helix	trans	-64.3	-34.5	171.9	-76.1	-85.7	0	0	0	111.6	A123 S127 I474 T475 V481 M482	A123-F477 HydrophobicContact CB-CD1 4.08Å; A123-F477 HydrophobicContact CB-CD2 4.5Å; A123-F477 HydrophobicContact CB-CE1 4.26Å; A123-F477 HydrophobicContact CB-CG 4.21Å; S127-F477 WeakPolarHBondContact OG-CE2 3.26Å; I474-F477 PolarHBondContact O-N 3.22Å; T475-F477 PolarHBondContact O-N 2.83Å; F477-V481 HydrophobicContact CD1-CG2 4.05Å; F477-V481 WeakPolarHBondContact O-CA 3.41Å; F477-V481 VanDerWaalsContact O-CB 3.24Å; F477-V481 WeakPolarHBondContact O-CB 3.46Å; F477-V481 PolarHBondContact O-N 3.14Å; F477-V481 VanDerWaalsContact O-N 3.15Å; F477-M482 PolarHBondContact O-N 2.93Å
478	I	93.7	Very high	90	Very high	30 Å²	30	36.1 Å²	36.1	15%	0.154	19%	0.191	C	C	.	.	I	π-helix	trans	-76	-49.3	176.2	-57.2	-57.5	0	0	0	110.8	F329 I474 T475 P476 Q480 M482 L483 T490 V493 Y494	F329-I478 HydrophobicContact CE2-CB 4.26Å; F329-I478 HydrophobicContact CE2-CG1 3.89Å; F329-I478 HydrophobicContact CZ-CB 4.24Å; F329-I478 HydrophobicContact CZ-CG1 4.01Å; F329-I478 HydrophobicContact CZ-CG2 4.12Å; I474-I478 HydrophobicContact CG2-CG1 4.17Å; I474-I478 PolarHBondContact O-N 3.42Å; T475-I478 CarbonylContact O-C 3.56Å; T475-I478 PolarHBondContact O-N 3.37Å; T475-I478 VanDerWaalsContact O-N 3.07Å; P476-I478 VanDerWaalsContact C-N 3.25Å; P476-I478 PolarHBondContact O-N 2.95Å; I478-Q480 PolarHBondContact O-N 3.33Å; I478-M482 HydrophobicContact CD1-SD 4.02Å; I478-M482 HydrophobicContact CG2-CE 3.87Å; I478-M482 VanDerWaalsContact O-CB 3.31Å; I478-M482 WeakPolarHBondContact O-CB 3.34Å; I478-L483 PolarHBondContact O-N 3.02Å; I478-T490 HydrophobicContact CG2-CG2 4.2Å; I478-T490 WeakPolarHBondContact O-CG2 3.42Å; I478-V493 HydrophobicContact CG2-CB 4.48Å; I478-V493 HydrophobicContact CG2-CG1 4.16Å; I478-Y494 HydrophobicContact CG2-CE2 3.86Å
479	A	89.8	Confident	89.8	Confident	0 Å²	0	40 Å²	40	0%	0	21%	0.21	C	C	.	.	I	π-helix	trans	-67.4	-32.7	-177.7	0	0	0	0	0	113.7	L336 T475 L483 Y494	L336-A479 HydrophobicContact CB-CB 3.86Å; T475-A479 WeakPolarHBondContact O-CB 3.33Å; T475-A479 PolarHBondContact O-N 3.5Å; A479-L483 WeakPolarHBondContact O-CB 3.45Å; A479-L483 WeakPolarHBondContact O-CD2 3.47Å; A479-Y494 WeakPolarHBondContact CB-OH 3.31Å; A479-Y494 PolarHBondContact N-OH 3.46Å
480	Q	87.4	Confident	89.7	Confident	4 Å²	4	39 Å²	39	2%	0.019	21%	0.206	C	C	.	.	I	π-helix	trans	-113.1	-35.8	-169.6	-52.4	-176.7	-70.5	0	0	112.9	A108 S119 A123 T126 E340 P476 I478	A108-Q480 VanDerWaalsContact CB-NE2 3.29Å; S119-Q480 WeakPolarHBondContact CB-O 3.43Å; A123-Q480 VanDerWaalsContact CA-OE1 3.28Å; A123-Q480 HydrophobicContact CB-CB 4.33Å; T126-Q480 PolarHBondContact OG1-OE1 2.95Å; E340-Q480 PolarHBondContact OE1-NE2 2.88Å; P476-Q480 WeakPolarHBondContact O-CA 3.49Å; P476-Q480 WeakPolarHBondContact O-CB 3.36Å; P476-Q480 WeakPolarHBondContact O-CG 3.45Å; P476-Q480 PolarHBondContact O-N 3.28Å; I478-Q480 PolarHBondContact O-N 3.33Å
481	V	89.4	Confident	89.5	Confident	46 Å²	46	36.7 Å²	36.7	28%	0.279	19%	0.193	S	C	.	.	I	π-helix	trans	-91.5	-47.8	178.8	-172	0	0	0	0	111.5	W120 A123 F477 L483 E484	W120-V481 HydrophobicContact CB-CG2 4.28Å; A123-V481 HydrophobicContact CB-CG2 3.66Å; F477-V481 HydrophobicContact CD1-CG2 4.05Å; F477-V481 WeakPolarHBondContact O-CA 3.41Å; F477-V481 VanDerWaalsContact O-CB 3.24Å; F477-V481 WeakPolarHBondContact O-CB 3.46Å; F477-V481 PolarHBondContact O-N 3.14Å; F477-V481 VanDerWaalsContact O-N 3.15Å; V481-L483 VanDerWaalsContact C-N 3.26Å; V481-L483 PolarHBondContact O-N 3.35Å; V481-E484 PolarHBondContact O-N 3.38Å
482	M	87.4	Confident	89.4	Confident	37 Å²	37	38.6 Å²	38.6	18%	0.182	21%	0.208	C	C	.	.	I	π-helix	trans	-70.6	-27.4	-177.2	-154.7	178.9	76.9	0	0	112.2	F477 I478 E484 S485 S486 L489 T490 V493	F477-M482 PolarHBondContact O-N 2.93Å; I478-M482 HydrophobicContact CD1-SD 4.02Å; I478-M482 HydrophobicContact CG2-CE 3.87Å; I478-M482 VanDerWaalsContact O-CB 3.31Å; I478-M482 WeakPolarHBondContact O-CB 3.34Å; M482-E484 VanDerWaalsContact C-N 3.32Å; M482-E484 PolarHBondContact O-N 3.42Å; M482-S485 PolarHBondContact O-N 3.02Å; M482-S485 VanDerWaalsContact O-N 3.16Å; M482-S486 PolarHBondContact O-N 3.46Å; M482-L489 VanDerWaalsContact CE-C 3.41Å; M482-L489 HydrophobicContact CE-CB 4.16Å; M482-L489 HydrophobicContact CE-CD2 4.22Å; M482-L489 HydrophobicContact CE-CG 3.7Å; M482-L489 WeakPolarHBondContact CE-O 3.36Å; M482-L489 HydrophobicContact CG-CD2 4Å; M482-L489 HydrophobicContact CG-CG 4.45Å; M482-L489 HydrophobicContact SD-CD2 3.85Å; M482-L489 HydrophobicContact SD-CG 3.95Å; M482-T490 VanDerWaalsContact C-OG1 3.28Å; M482-T490 HydrophobicContact CE-CG2 4.5Å; M482-T490 WeakPolarHBondContact CE-OG1 3.42Å; M482-T490 PolarHBondContact O-OG1 3.47Å; M482-V493 HydrophobicContact CE-CB 4.11Å; M482-V493 HydrophobicContact CE-CG2 3.72Å; M482-V493 HydrophobicContact SD-CG2 4.38Å
483	L	84.2	Confident	89.5	Confident	11 Å²	11	41.1 Å²	41.1	6%	0.058	22%	0.223	C	C	.	.	H	α-helix	trans	-61.4	-38.7	175.9	-169.5	74	0	0	0	112.5	L337 E340 I478 A479 V481 S485 S486 V487 T490	L337-L483 HydrophobicContact CD1-CD1 3.48Å; L337-L483 VanDerWaalsContact CD1-CD1 3.48Å; L337-L483 HydrophobicContact CD1-CD2 3.9Å; L337-L483 HydrophobicContact CD1-CG 4.3Å; E340-L483 HydrophobicContact CB-CD2 3.39Å; E340-L483 HydrophobicContact CG-CD2 4.22Å; I478-L483 PolarHBondContact O-N 3.02Å; A479-L483 WeakPolarHBondContact O-CB 3.45Å; A479-L483 WeakPolarHBondContact O-CD2 3.47Å; V481-L483 VanDerWaalsContact C-N 3.26Å; V481-L483 PolarHBondContact O-N 3.35Å; L483-S485 VanDerWaalsContact C-N 3.28Å; L483-S485 PolarHBondContact O-N 3.48Å; L483-S486 CarbonylContact O-C 3.14Å; L483-S486 PolarHBondContact O-N 2.81Å; L483-V487 HydrophobicContact CD1-CB 4.27Å; L483-V487 HydrophobicContact CD1-CG1 4.14Å; L483-V487 HydrophobicContact CD1-CG2 4.04Å; L483-T490 VanDerWaalsContact CA-OG1 3.31Å; L483-T490 WeakPolarHBondContact CA-OG1 3.32Å; L483-T490 HydrophobicContact CB-CG2 4.44Å; L483-T490 HydrophobicContact CD1-CG2 3.96Å; L483-T490 PolarHBondContact N-OG1 3.4Å
484	E	78.9	Confident	89.5	Confident	52 Å²	52	39.2 Å²	39.2	24%	0.243	21%	0.213	C	C	.	.	H	α-helix	trans	-62.2	-37	174.9	-69.5	-170	158.6	0	0	112.3	S119 L363 V481 M482	S119-E484 WeakPolarHBondContact CB-OE1 3.47Å; S119-E484 VanDerWaalsContact CB-OE2 3.29Å; S119-E484 WeakPolarHBondContact CB-OE2 3.06Å; S119-E484 PolarHBondContact OG-OE1 2.98Å; S119-E484 PolarHBondContact OG-OE2 3.3Å; L363-E484 HydrophobicContact CB-CG 4.31Å; V481-E484 PolarHBondContact O-N 3.38Å; M482-E484 VanDerWaalsContact C-N 3.32Å; M482-E484 PolarHBondContact O-N 3.42Å
485	S	81.3	Confident	89.5	Confident	95 Å²	95	36 Å²	36	66%	0.664	20%	0.197	S	C	*	.	H	α-helix	trans	-73.7	-45	178.2	-176.5	0	0	0	0	111.6	M482 L483	M482-S485 PolarHBondContact O-N 3.02Å; M482-S485 VanDerWaalsContact O-N 3.16Å; L483-S485 VanDerWaalsContact C-N 3.28Å; L483-S485 PolarHBondContact O-N 3.48Å
486	S	84.3	Confident	89.5	Confident	39 Å²	39	37.4 Å²	37.4	27%	0.273	21%	0.211	S	C	.	.			trans	-165.1	121.3	179.5	-177.5	0	0	0	0	111.9	M482 L483 Y488 L489 T490	M482-S486 PolarHBondContact O-N 3.46Å; L483-S486 CarbonylContact O-C 3.14Å; L483-S486 PolarHBondContact O-N 2.81Å; S486-Y488 VanDerWaalsContact C-N 3.34Å; S486-Y488 PolarHBondContact O-N 3.04Å; S486-Y488 PolarHBondContact OG-N 3.05Å; S486-L489 PolarHBondContact O-N 3.31Å; S486-L489 PolarHBondContact OG-N 2.68Å; S486-T490 PolarHBondContact O-N 2.73Å; S486-T490 PolarHBondContact O-OG1 2.71Å
487	V	83.4	Confident	89.6	Confident	40 Å²	40	38.2 Å²	38.2	24%	0.242	22%	0.217	C	C	.	.	H	α-helix	trans	-61.3	-43.2	172.3	-176.8	0	0	0	0	111.2	L341 L483 L489 T490 L491	L341-V487 HydrophobicContact CD1-CG1 4.24Å; L483-V487 HydrophobicContact CD1-CB 4.27Å; L483-V487 HydrophobicContact CD1-CG1 4.14Å; L483-V487 HydrophobicContact CD1-CG2 4.04Å; V487-L489 PolarHBondContact O-N 3.37Å; V487-T490 PolarHBondContact O-N 3.08Å; V487-L491 HydrophobicContact CG1-CD1 3.97Å; V487-L491 HydrophobicContact CG1-CG 4.39Å; V487-L491 WeakPolarHBondContact O-CG 3.44Å; V487-L491 PolarHBondContact O-N 3.15Å
488	Y	86.3	Confident	89.8	Confident	131 Å²	131	34.1 Å²	34.1	51%	0.514	20%	0.199	S	C	.	.	H	α-helix	trans	-62.8	-41.1	179.6	-59.8	-61.5	0	0	0	112.7	F418 S486 T490 A492	F418-Y488 HydrophobicContact CB-CD1 4.36Å; F418-Y488 HydrophobicContact CB-CE1 4.49Å; F418-Y488 AromaticContact CD1-CD1 3.96Å; F418-Y488 HydrophobicContact CD1-CD1 3.96Å; F418-Y488 HydrophobicContact CG-CD1 4.2Å; F418-Y488 WeakPolarHBondContact CZ-O 3.33Å; F418-Y488 VanDerWaalsContact O-CE1 3.26Å; F418-Y488 WeakPolarHBondContact O-CE1 3.07Å; S486-Y488 VanDerWaalsContact C-N 3.34Å; S486-Y488 PolarHBondContact O-N 3.04Å; S486-Y488 PolarHBondContact OG-N 3.05Å; Y488-T490 VanDerWaalsContact C-N 3.3Å; Y488-T490 PolarHBondContact O-N 2.66Å; Y488-A492 VanDerWaalsContact O-CB 3.25Å; Y488-A492 WeakPolarHBondContact O-CB 3.45Å; Y488-A492 PolarHBondContact O-N 2.95Å
489	L	89.4	Confident	89.9	Confident	84 Å²	84	36.1 Å²	36.1	44%	0.44	21%	0.21	S	C	.	.	H	α-helix	trans	-63.6	-40.1	176.5	-172.7	62.6	0	0	0	110.9	M482 S486 V487 A492 V493	M482-L489 VanDerWaalsContact CE-C 3.41Å; M482-L489 HydrophobicContact CE-CB 4.16Å; M482-L489 HydrophobicContact CE-CD2 4.22Å; M482-L489 HydrophobicContact CE-CG 3.7Å; M482-L489 WeakPolarHBondContact CE-O 3.36Å; M482-L489 HydrophobicContact CG-CD2 4Å; M482-L489 HydrophobicContact CG-CG 4.45Å; M482-L489 HydrophobicContact SD-CD2 3.85Å; M482-L489 HydrophobicContact SD-CG 3.95Å; S486-L489 PolarHBondContact O-N 3.31Å; S486-L489 PolarHBondContact OG-N 2.68Å; V487-L489 PolarHBondContact O-N 3.37Å; L489-A492 WeakPolarHBondContact O-CB 3.43Å; L489-A492 PolarHBondContact O-N 3.43Å; L489-V493 WeakPolarHBondContact O-CG2 3.31Å; L489-V493 PolarHBondContact O-N 2.84Å
490	T	90.1	Very high	90.3	Very high	0 Å²	0	41 Å²	41	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-63.9	-49.2	179.5	-57.3	0	0	0	0	111.9	L337 I478 M482 L483 S486 V487 Y488 A492 V493 Y494	L337-T490 HydrophobicContact CD1-CG2 4.23Å; I478-T490 HydrophobicContact CG2-CG2 4.2Å; I478-T490 WeakPolarHBondContact O-CG2 3.42Å; M482-T490 VanDerWaalsContact C-OG1 3.28Å; M482-T490 HydrophobicContact CE-CG2 4.5Å; M482-T490 WeakPolarHBondContact CE-OG1 3.42Å; M482-T490 PolarHBondContact O-OG1 3.47Å; L483-T490 VanDerWaalsContact CA-OG1 3.31Å; L483-T490 WeakPolarHBondContact CA-OG1 3.32Å; L483-T490 HydrophobicContact CB-CG2 4.44Å; L483-T490 HydrophobicContact CD1-CG2 3.96Å; L483-T490 PolarHBondContact N-OG1 3.4Å; S486-T490 PolarHBondContact O-N 2.73Å; S486-T490 PolarHBondContact O-OG1 2.71Å; V487-T490 PolarHBondContact O-N 3.08Å; Y488-T490 VanDerWaalsContact C-N 3.3Å; Y488-T490 PolarHBondContact O-N 2.66Å; T490-A492 VanDerWaalsContact C-N 3.31Å; T490-A492 PolarHBondContact O-N 2.71Å; T490-V493 PolarHBondContact O-N 3.48Å; T490-Y494 HydrophobicContact CG2-CD2 4.06Å; T490-Y494 HydrophobicContact CG2-CE2 3.7Å; T490-Y494 VanDerWaalsContact O-CD2 3.22Å; T490-Y494 WeakPolarHBondContact O-CD2 3.36Å; T490-Y494 PolarHBondContact O-N 3.47Å
491	L	90.6	Very high	90.7	Very high	2 Å²	2	40.8 Å²	40.8	1%	0.01	23%	0.234	C	C	.	.	H	α-helix	trans	-64	-35.5	174.7	-64	172.1	0	0	0	112.2	L337 L417 F418 V487 S495	L337-L491 HydrophobicContact CD2-CD2 3.89Å; L417-L491 HydrophobicContact CB-CD1 3.68Å; L417-L491 HydrophobicContact CB-CD2 4.29Å; L417-L491 HydrophobicContact CD1-CD2 4.07Å; F418-L491 HydrophobicContact CD2-CB 4.07Å; F418-L491 HydrophobicContact CD2-CD1 4.31Å; F418-L491 HydrophobicContact CE2-CB 3.49Å; F418-L491 VanDerWaalsContact CE2-CB 3.49Å; F418-L491 HydrophobicContact CZ-CB 4.22Å; V487-L491 HydrophobicContact CG1-CD1 3.97Å; V487-L491 HydrophobicContact CG1-CG 4.39Å; V487-L491 WeakPolarHBondContact O-CG 3.44Å; V487-L491 PolarHBondContact O-N 3.15Å; L491-S495 VanDerWaalsContact O-CB 3.31Å; L491-S495 WeakPolarHBondContact O-CB 3.27Å; L491-S495 PolarHBondContact O-N 3.17Å; L491-S495 PolarHBondContact O-OG 3.32Å
492	A	93	Very high	91.1	Very high	39 Å²	39	38.9 Å²	38.9	32%	0.322	22%	0.223	S	C	.	.	H	α-helix	trans	-63.1	-41.3	175.6	0	0	0	0	0	112.2	F418 Y488 L489 T490 S495 G496	F418-A492 HydrophobicContact CZ-CB 3.84Å; Y488-A492 VanDerWaalsContact O-CB 3.25Å; Y488-A492 WeakPolarHBondContact O-CB 3.45Å; Y488-A492 PolarHBondContact O-N 2.95Å; L489-A492 WeakPolarHBondContact O-CB 3.43Å; L489-A492 PolarHBondContact O-N 3.43Å; T490-A492 VanDerWaalsContact C-N 3.31Å; T490-A492 PolarHBondContact O-N 2.71Å; A492-S495 WeakPolarHBondContact CA-OG 3.49Å; A492-S495 PolarHBondContact O-OG 3.08Å; A492-G496 WeakPolarHBondContact O-CA 3.43Å; A492-G496 PolarHBondContact O-N 3.16Å
493	V	95.6	Very high	91.5	Very high	53 Å²	53	41.8 Å²	41.8	32%	0.321	24%	0.239	S	C	.	.	H	α-helix	trans	-67.2	-45.6	179.2	170.1	0	0	0	0	111.2	F329 I478 M482 L489 T490 C497	F329-V493 HydrophobicContact CE1-CG1 4.14Å; F329-V493 HydrophobicContact CZ-CG1 3.88Å; I478-V493 HydrophobicContact CG2-CB 4.48Å; I478-V493 HydrophobicContact CG2-CG1 4.16Å; M482-V493 HydrophobicContact CE-CB 4.11Å; M482-V493 HydrophobicContact CE-CG2 3.72Å; M482-V493 HydrophobicContact SD-CG2 4.38Å; L489-V493 WeakPolarHBondContact O-CG2 3.31Å; L489-V493 PolarHBondContact O-N 2.84Å; T490-V493 PolarHBondContact O-N 3.48Å; V493-C497 WeakPolarHBondContact O-CB 3.5Å; V493-C497 PolarHBondContact O-N 2.94Å
494	Y	95.3	Very high	92	Very high	3 Å²	3	41.7 Å²	41.7	1%	0.012	24%	0.239	C	C	.	.	H	α-helix	trans	-64.5	-48	176.9	-74.1	-62.1	0	0	0	112.5	F329 G333 L337 T475 I478 A479 T490 C497 C498	F329-Y494 AromaticContact CD1-CD1 3.75Å; F329-Y494 HydrophobicContact CD1-CD1 3.75Å; F329-Y494 AromaticContact CD1-CE1 3.81Å; F329-Y494 HydrophobicContact CD1-CE1 3.81Å; F329-Y494 HydrophobicContact CD2-CE1 4.34Å; F329-Y494 AromaticContact CE1-CD1 3.3Å; F329-Y494 HydrophobicContact CE1-CD1 3.3Å; F329-Y494 AromaticContact CE1-CE1 3.4Å; F329-Y494 HydrophobicContact CE1-CE1 3.4Å; F329-Y494 HydrophobicContact CE1-CG 4.27Å; F329-Y494 AromaticContact CE2-CE1 3.97Å; F329-Y494 HydrophobicContact CE2-CE1 3.97Å; F329-Y494 HydrophobicContact CG-CE1 4.27Å; F329-Y494 AromaticContact CZ-CD1 3.84Å; F329-Y494 HydrophobicContact CZ-CD1 3.84Å; F329-Y494 AromaticContact CZ-CE1 3.48Å; F329-Y494 HydrophobicContact CZ-CE1 3.48Å; F329-Y494 VanDerWaalsContact CZ-CE1 3.48Å; G333-Y494 WeakPolarHBondContact CA-OH 3.47Å; L337-Y494 HydrophobicContact CD2-CD2 4.33Å; L337-Y494 HydrophobicContact CD2-CE2 4.38Å; T475-Y494 PolarHBondContact O-OH 2.99Å; T475-Y494 PolarHBondContact OG1-OH 3.42Å; I478-Y494 HydrophobicContact CG2-CE2 3.86Å; A479-Y494 WeakPolarHBondContact CB-OH 3.31Å; A479-Y494 PolarHBondContact N-OH 3.46Å; T490-Y494 HydrophobicContact CG2-CD2 4.06Å; T490-Y494 HydrophobicContact CG2-CE2 3.7Å; T490-Y494 VanDerWaalsContact O-CD2 3.22Å; T490-Y494 WeakPolarHBondContact O-CD2 3.36Å; T490-Y494 PolarHBondContact O-N 3.47Å; Y494-C497 PolarHBondContact O-N 3.05Å; Y494-C498 WeakPolarHBondContact O-CB 3.24Å; Y494-C498 PolarHBondContact O-N 3.41Å
495	S	95	Very high	92.7	Very high	4 Å²	4	39.2 Å²	39.2	3%	0.028	23%	0.228	C	C	.	.	H	α-helix	trans	-65.6	-42.7	178.9	57.7	0	0	0	0	112.2	S411 L491 A492 C498 L499	S411-S495 PolarHBondContact OG-O 3.34Å; L491-S495 VanDerWaalsContact O-CB 3.31Å; L491-S495 WeakPolarHBondContact O-CB 3.27Å; L491-S495 PolarHBondContact O-N 3.17Å; L491-S495 PolarHBondContact O-OG 3.32Å; A492-S495 WeakPolarHBondContact CA-OG 3.49Å; A492-S495 PolarHBondContact O-OG 3.08Å; S495-C498 PolarHBondContact O-N 3.44Å; S495-L499 WeakPolarHBondContact O-CB 3.28Å; S495-L499 WeakPolarHBondContact O-CG 3.32Å; S495-L499 PolarHBondContact O-N 2.93Å
496	G	96.3	Very high	93.3	Very high	28 Å²	28	38 Å²	38	29%	0.289	22%	0.219	S	C	.	.	H	α-helix	trans	-61.9	-44.6	176	0	0	0	0	0	112.5	A492 C498 L499 L500	A492-G496 WeakPolarHBondContact O-CA 3.43Å; A492-G496 PolarHBondContact O-N 3.16Å; G496-C498 PolarHBondContact O-N 2.88Å; G496-L499 PolarHBondContact O-N 2.88Å; G496-L500 WeakPolarHBondContact O-CG 3.33Å; G496-L500 PolarHBondContact O-N 3.44Å
497	C	97.1	Very high	93.7	Very high	18 Å²	18	43.3 Å²	43.3	12%	0.122	24%	0.237	C	C	.	.	H	α-helix	trans	-60.8	-45.8	176.3	-170.6	0	0	0	0	111.6	S326 F329 V493 Y494 L500 A501	S326-C497 PolarHBondContact OG-SG 2.83Å; F329-C497 HydrophobicContact CD1-CB 4.26Å; F329-C497 HydrophobicContact CE1-CB 4.18Å; V493-C497 WeakPolarHBondContact O-CB 3.5Å; V493-C497 PolarHBondContact O-N 2.94Å; Y494-C497 PolarHBondContact O-N 3.05Å; C497-L500 PolarHBondContact O-N 3.41Å; C497-A501 WeakPolarHBondContact O-CB 3.35Å; C497-A501 PolarHBondContact O-N 3.18Å
498	C	96.4	Very high	94	Very high	0 Å²	0	41.4 Å²	41.4	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-67.6	-38	177.9	-77.4	0	0	0	0	113.2	S330 F407 F410 S411 Y494 S495 G496 L500 A501 A502	S330-C498 VanDerWaalsContact CB-SG 3.56Å; S330-C498 PolarHBondContact OG-SG 3.3Å; F407-C498 HydrophobicContact CB-CB 4.44Å; F407-C498 WeakPolarHBondContact CB-O 3.2Å; F407-C498 HydrophobicContact CD1-CB 4Å; F410-C498 HydrophobicContact CD1-CB 3.82Å; F410-C498 WeakPolarHBondContact CD1-SG 3.35Å; F410-C498 HydrophobicContact CE1-CB 4.32Å; F410-C498 VanDerWaalsContact CE1-SG 3.52Å; S411-C498 WeakPolarHBondContact OG-CB 3.24Å; Y494-C498 WeakPolarHBondContact O-CB 3.24Å; Y494-C498 PolarHBondContact O-N 3.41Å; S495-C498 PolarHBondContact O-N 3.44Å; G496-C498 PolarHBondContact O-N 2.88Å; C498-L500 VanDerWaalsContact C-N 3.34Å; C498-L500 PolarHBondContact O-N 3.08Å; C498-A501 CarbonylContact O-C 3.55Å; C498-A501 WeakPolarHBondContact O-CB 3.24Å; C498-A501 PolarHBondContact O-N 3.34Å; C498-A501 VanDerWaalsContact O-N 3.14Å; C498-A502 PolarHBondContact O-N 3.39Å
499	L	96.9	Very high	93.9	Very high	73 Å²	73	39.1 Å²	39.1	38%	0.382	23%	0.227	S	C	.	.	H	α-helix	trans	-62.6	-42.2	174.1	-74.7	173.9	0	0	0	111.7	S411 L415 S495 G496 A501 A502 L503	S411-L499 PolarHBondContact OG-N 2.8Å; L415-L499 HydrophobicContact CD1-CD1 4.5Å; S495-L499 WeakPolarHBondContact O-CB 3.28Å; S495-L499 WeakPolarHBondContact O-CG 3.32Å; S495-L499 PolarHBondContact O-N 2.93Å; G496-L499 PolarHBondContact O-N 2.88Å; L499-A501 VanDerWaalsContact C-N 3.3Å; L499-A501 PolarHBondContact O-N 2.85Å; L499-A502 WeakPolarHBondContact O-CB 3.37Å; L499-A502 PolarHBondContact O-N 2.8Å; L499-L503 WeakPolarHBondContact O-CG 3.42Å; L499-L503 PolarHBondContact O-N 2.99Å
500	L	97.3	Very high	93.5	Very high	101 Å²	101	35.9 Å²	35.9	53%	0.529	21%	0.21	S	C	.	.	H	α-helix	trans	-63	-38.7	173	-68.6	173.1	0	0	0	111.2	F322 G496 C497 C498 A502 L503 A504	F322-L500 HydrophobicContact CE1-CB 3.78Å; F322-L500 HydrophobicContact CZ-CB 3.8Å; G496-L500 WeakPolarHBondContact O-CG 3.33Å; G496-L500 PolarHBondContact O-N 3.44Å; C497-L500 PolarHBondContact O-N 3.41Å; C498-L500 VanDerWaalsContact C-N 3.34Å; C498-L500 PolarHBondContact O-N 3.08Å; L500-A502 VanDerWaalsContact C-N 3.35Å; L500-L503 PolarHBondContact O-N 3.44Å; L500-A504 WeakPolarHBondContact O-CB 3.47Å; L500-A504 PolarHBondContact O-N 3.4Å
501	A	96.8	Very high	93.3	Very high	0 Å²	0	38.5 Å²	38.5	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-68.8	-33	177.3	0	0	0	0	0	112.4	F322 F407 C497 C498 L499 A504 S505	F322-A501 HydrophobicContact CE1-CB 4.16Å; F407-A501 HydrophobicContact CD1-CB 4.05Å; F407-A501 HydrophobicContact CD2-CB 3.91Å; F407-A501 HydrophobicContact CE1-CB 3.92Å; F407-A501 HydrophobicContact CE2-CB 3.78Å; F407-A501 HydrophobicContact CG-CB 4.04Å; F407-A501 HydrophobicContact CZ-CB 3.78Å; C497-A501 WeakPolarHBondContact O-CB 3.35Å; C497-A501 PolarHBondContact O-N 3.18Å; C498-A501 CarbonylContact O-C 3.55Å; C498-A501 WeakPolarHBondContact O-CB 3.24Å; C498-A501 PolarHBondContact O-N 3.34Å; C498-A501 VanDerWaalsContact O-N 3.14Å; L499-A501 VanDerWaalsContact C-N 3.3Å; L499-A501 PolarHBondContact O-N 2.85Å; A501-A504 PolarHBondContact O-N 3.24Å; A501-S505 WeakPolarHBondContact O-CB 3.31Å; A501-S505 PolarHBondContact O-N 3.25Å; A501-S505 PolarHBondContact O-OG 3.27Å
502	A	96.6	Very high	92.7	Very high	6 Å²	6	38.5 Å²	38.5	5%	0.05	22%	0.222	C	C	.	.	H	α-helix	trans	-63.7	-44.8	171.5	0	0	0	0	0	111.2	F407 V408 C498 L499 L500 S505 C506	F407-A502 HydrophobicContact CB-CB 3.76Å; V408-A502 HydrophobicContact CG2-CB 3.79Å; C498-A502 PolarHBondContact O-N 3.39Å; L499-A502 WeakPolarHBondContact O-CB 3.37Å; L499-A502 PolarHBondContact O-N 2.8Å; L500-A502 VanDerWaalsContact C-N 3.35Å; A502-S505 WeakPolarHBondContact O-CB 3.39Å; A502-S505 PolarHBondContact O-N 2.86Å; A502-C506 PolarHBondContact O-N 3.37Å; A502-C506 PolarHBondContact O-SG 2.91Å
503	L	96.1	Very high	91.8	Very high	98 Å²	98	41.2 Å²	41.2	51%	0.513	23%	0.227	S	C	.	.	H	α-helix	trans	-62.1	-46.6	173.8	-68	173.9	0	0	0	111.1	L499 L500 S505 C506 F507	L499-L503 WeakPolarHBondContact O-CG 3.42Å; L499-L503 PolarHBondContact O-N 2.99Å; L500-L503 PolarHBondContact O-N 3.44Å; L503-S505 VanDerWaalsContact C-N 3.27Å; L503-S505 PolarHBondContact O-N 3.39Å; L503-C506 CarbonylContact O-C 3.51Å; L503-C506 WeakPolarHBondContact O-CA 3.35Å; L503-C506 WeakPolarHBondContact O-CB 3.25Å; L503-C506 PolarHBondContact O-N 2.73Å; L503-F507 HydrophobicContact CB-CE2 4.44Å; L503-F507 WeakPolarHBondContact O-CD2 3.49Å; L503-F507 PolarHBondContact O-N 3.5Å
504	A	95	Very high	90.1	Very high	9 Å²	9	42.4 Å²	42.4	7%	0.074	25%	0.25	C	C	.	.	H	α-helix	trans	-57.3	-41.8	175.9	0	0	0	0	0	111.8	L319 F322 I323 L500 A501 C506 F507 L508	L319-A504 HydrophobicContact CD2-CB 3.82Å; F322-A504 HydrophobicContact CD1-CB 3.92Å; F322-A504 HydrophobicContact CE1-CB 4.45Å; I323-A504 HydrophobicContact CD1-CB 4.5Å; I323-A504 HydrophobicContact CG1-CB 4.22Å; L500-A504 WeakPolarHBondContact O-CB 3.47Å; L500-A504 PolarHBondContact O-N 3.4Å; A501-A504 PolarHBondContact O-N 3.24Å; A504-C506 VanDerWaalsContact C-N 3.33Å; A504-C506 PolarHBondContact O-N 3.31Å; A504-F507 PolarHBondContact O-N 3.44Å; A504-F507 VanDerWaalsContact O-N 3.1Å; A504-L508 PolarHBondContact O-N 2.9Å
505	S	94.4	Very high	88.6	Confident	0 Å²	0	47.3 Å²	47.3	0%	0	27%	0.268	C	S	.	.	H	α-helix	trans	-61.1	-41.9	174.3	-60.5	0	0	0	0	111.2	K400 A501 A502 L503 F507 L508	K400-S505 WeakPolarHBondContact CE-O 3.27Å; K400-S505 WeakPolarHBondContact CG-O 3.34Å; A501-S505 WeakPolarHBondContact O-CB 3.31Å; A501-S505 PolarHBondContact O-N 3.25Å; A501-S505 PolarHBondContact O-OG 3.27Å; A502-S505 WeakPolarHBondContact O-CB 3.39Å; A502-S505 PolarHBondContact O-N 2.86Å; L503-S505 VanDerWaalsContact C-N 3.27Å; L503-S505 PolarHBondContact O-N 3.39Å; S505-F507 VanDerWaalsContact C-N 3.28Å; S505-F507 PolarHBondContact O-N 3.3Å; S505-L508 WeakPolarHBondContact O-CB 3.44Å; S505-L508 PolarHBondContact O-N 2.94Å
506	C	92.7	Very high	86.5	Confident	71 Å²	71	50 Å²	50	48%	0.48	30%	0.297	S	S	.	.	H	α-helix	trans	-66	-24.7	174.2	-72.3	0	0	0	0	114	K400 A502 L503 A504	K400-C506 WeakPolarHBondContact CE-O 3.04Å; K400-C506 PolarHBondContact NZ-O 3.26Å; A502-C506 PolarHBondContact O-N 3.37Å; A502-C506 PolarHBondContact O-SG 2.91Å; L503-C506 CarbonylContact O-C 3.51Å; L503-C506 WeakPolarHBondContact O-CA 3.35Å; L503-C506 WeakPolarHBondContact O-CB 3.25Å; L503-C506 PolarHBondContact O-N 2.73Å; A504-C506 VanDerWaalsContact C-N 3.33Å; A504-C506 PolarHBondContact O-N 3.31Å
507	F	93	Very high	84.5	Confident	149 Å²	149	52.9 Å²	52.9	65%	0.654	31%	0.305	S	S	*	.	H	α-helix	trans	-88.2	-4.4	176.2	-73	-63.6	0	0	0	114.5	L319 L503 A504 S505	L319-F507 HydrophobicContact CD1-CB 4.13Å; L503-F507 HydrophobicContact CB-CE2 4.44Å; L503-F507 WeakPolarHBondContact O-CD2 3.49Å; L503-F507 PolarHBondContact O-N 3.5Å; A504-F507 PolarHBondContact O-N 3.44Å; A504-F507 VanDerWaalsContact O-N 3.1Å; S505-F507 VanDerWaalsContact C-N 3.28Å; S505-F507 PolarHBondContact O-N 3.3Å
508	L	90.9	Very high	82.2	Confident	0 Å²	0	54.3 Å²	54.3	0%	0	31%	0.31	C	S	.	.			trans	-56.8	128.5	174.9	-75.6	169.1	0	0	0	111	T316 L319 L320 I323 K400 M403 Y447 A504 S505 I510	T316-L508 HydrophobicContact CG2-CD2 4.44Å; L319-L508 HydrophobicContact CB-CD2 3.92Å; L319-L508 HydrophobicContact CD1-CD2 4.31Å; L320-L508 HydrophobicContact CD2-CD2 4.2Å; L320-L508 HydrophobicContact CG-CD2 4.18Å; I323-L508 HydrophobicContact CD1-CD1 3.75Å; I323-L508 HydrophobicContact CD1-CD2 4.29Å; I323-L508 HydrophobicContact CD1-CG 4.1Å; K400-L508 HydrophobicContact CD-CB 4.09Å; K400-L508 WeakPolarHBondContact CE-O 3.44Å; K400-L508 HydrophobicContact CG-CB 4.17Å; K400-L508 HydrophobicContact CG-CD1 4.44Å; K400-L508 PolarHBondContact NZ-O 3.41Å; M403-L508 HydrophobicContact CE-CD1 3.6Å; Y447-L508 HydrophobicContact CD1-CD1 4.33Å; Y447-L508 HydrophobicContact CE1-CD1 3.62Å; Y447-L508 HydrophobicContact CE1-CD2 4.05Å; Y447-L508 HydrophobicContact CE1-CG 4.35Å; A504-L508 PolarHBondContact O-N 2.9Å; S505-L508 WeakPolarHBondContact O-CB 3.44Å; S505-L508 PolarHBondContact O-N 2.94Å; L508-I510 VanDerWaalsContact C-N 3.29Å; L508-I510 PolarHBondContact O-N 3.49Å
509	P	82.9	Confident	79.8	Confident	83 Å²	83	62.1 Å²	62.1	54%	0.539	35%	0.347	S	S	.	.	S	Bend	trans	-73.1	-21.1	-168.9	25.4	-32.5	0	0	0	113.6	T316	T316-P509 WeakPolarHBondContact OG1-CG 3.32Å
510	I	82.5	Confident	77.1	Confident	16 Å²	16	60.1 Å²	60.1	8%	0.082	34%	0.339	C	S	.	.			trans	-124.2	132.6	-168.8	-58.4	166.2	0	0	0	110.1	Y447 L508 T512 W525 M529	Y447-I510 WeakPolarHBondContact CE2-O 3.16Å; Y447-I510 PolarHBondContact OH-O 3.35Å; L508-I510 VanDerWaalsContact C-N 3.29Å; L508-I510 PolarHBondContact O-N 3.49Å; I510-T512 HydrophobicContact CG2-CG2 4.4Å; I510-W525 HydrophobicContact CD1-CZ2 4.43Å; I510-M529 HydrophobicContact CD1-SD 4.39Å
511	E	84.6	Confident	74.7	Confident	55 Å²	55	57.3 Å²	57.3	26%	0.257	33%	0.327	S	S	.	.			trans	-98.2	129.9	163.5	178.4	60.7	-105.7	0	0	108.6	R399 K400 K513 R515	R399-E511 PolarHBondContact N-OE1 2.9Å; K400-E511 VanDerWaalsContact CB-OE2 3.23Å; K400-E511 WeakPolarHBondContact CB-OE2 3.4Å; K400-E511 PolarHBondContact N-OE2 3.07Å; E511-K513 HydrophobicContact CG-CB 4.03Å; E511-K513 PolarHBondContact OE1-N 2.71Å; E511-R515 PolarHBondContact O-NE 3.25Å
512	T	78.8	Confident	72.2	Confident	2 Å²	2	60.8 Å²	60.8	1%	0.012	34%	0.344	C	S	.	.			trans	-98.9	-4.9	-173.5	56.9	0	0	0	0	113.2	R399 Y447 E450 V451 I510 G514 R515	R399-T512 WeakPolarHBondContact CD-OG1 3.45Å; R399-T512 WeakPolarHBondContact CG-OG1 3.26Å; Y447-T512 HydrophobicContact CD2-CG2 3.9Å; Y447-T512 HydrophobicContact CE2-CG2 3.76Å; E450-T512 HydrophobicContact CB-CG2 3.71Å; E450-T512 WeakPolarHBondContact OE2-CB 3.26Å; E450-T512 PolarHBondContact OE2-OG1 3.25Å; V451-T512 HydrophobicContact CG2-CG2 3.63Å; I510-T512 HydrophobicContact CG2-CG2 4.4Å; T512-G514 PolarHBondContact O-N 3.3Å; T512-G514 VanDerWaalsContact O-N 3.17Å; T512-R515 WeakPolarHBondContact O-CB 3.4Å; T512-R515 PolarHBondContact O-N 3.42Å
513	K	74.1	Confident	69.6	Low	97 Å²	97	71.1 Å²	71.1	42%	0.422	38%	0.381	S	S	.	.	T	Hydrogen-bonded Turn	trans	-50.7	121.9	178.1	-172.1	-177.6	179.8	176.1	0	112	D395 R396 E511 R515	D395-K513 WeakPolarHBondContact O-CE 3.33Å; D395-K513 PolarHBondContact O-NZ 2.92Å; R396-K513 PolarHBondContact O-NZ 3.17Å; E511-K513 HydrophobicContact CG-CB 4.03Å; E511-K513 PolarHBondContact OE1-N 2.71Å; K513-R515 VanDerWaalsContact C-N 3.27Å; K513-R515 PolarHBondContact O-N 3.09Å
514	G	60.3	Low	67.3	Low	78 Å²	78	71.8 Å²	71.8	80%	0.804	38%	0.382	S	S	*	.	T	Hydrogen-bonded Turn	trans	74.4	9.2	175.6	0	0	0	0	0	115.1	T512	T512-G514 PolarHBondContact O-N 3.3Å; T512-G514 VanDerWaalsContact O-N 3.17Å
515	R	62.2	Low	65.1	Low	105 Å²	105	71.9 Å²	71.9	40%	0.396	38%	0.38	S	S	.	.			trans	-88	135.4	173	-62.2	-170.9	-177.4	-165.6	-1	110.2	E511 T512 K513	E511-R515 PolarHBondContact O-NE 3.25Å; T512-R515 WeakPolarHBondContact O-CB 3.4Å; T512-R515 PolarHBondContact O-N 3.42Å; K513-R515 VanDerWaalsContact C-N 3.27Å; K513-R515 PolarHBondContact O-N 3.09Å
516	G	51.9	Low	63	Low	62 Å²	62	72.8 Å²	72.8	64%	0.639	39%	0.39	S	S	*	.			trans	-65.5	155.5	166.3	0	0	0	0	0	110.9	Q518	G516-Q518 PolarHBondContact O-N 3.17Å; G516-Q518 VanDerWaalsContact O-N 3.11Å
517	L	54.6	Low	60.7	Low	88 Å²	88	76.6 Å²	76.6	46%	0.461	40%	0.4	S	S	.	.			trans	-60.4	114.4	170.7	-75.7	160.5	0	0	0	108.1	M203 E519	M203-L517 HydrophobicContact CE-CD1 4.27Å; L517-E519 PolarHBondContact O-N 2.97Å
518	Q	48.8	Very low	58.7	Low	47 Å²	47	74.8 Å²	74.8	22%	0.22	39%	0.394	C	S	.	.			trans	-75.5	125.1	-172.1	-71.9	172.5	-39.9	0	0	111.2	T454 R457 G516 S520	T454-Q518 PolarHBondContact OG1-O 3.06Å; T454-Q518 VanDerWaalsContact OG1-O 3.12Å; R457-Q518 PolarHBondContact NH2-O 2.81Å; G516-Q518 PolarHBondContact O-N 3.17Å; G516-Q518 VanDerWaalsContact O-N 3.11Å; Q518-S520 VanDerWaalsContact C-N 3.33Å
519	E	45.6	Very low	56.5	Low	165 Å²	165	77.5 Å²	77.5	77%	0.771	41%	0.407	S	S	*	.			trans	-90.3	5.4	174.3	-70	-179.9	166	0	0	112.6	L517	L517-E519 PolarHBondContact O-N 2.97Å
520	S	40.6	Very low	54.7	Low	30 Å²	30	77.7 Å²	77.7	21%	0.21	41%	0.407	C	S	.	.			trans	-72.2	138.5	-172.3	48.5	0	0	0	0	113.3	Q518	Q518-S520 VanDerWaalsContact C-N 3.33Å
521	S	47	Very low	52.6	Low	42 Å²	42	79 Å²	79	29%	0.294	42%	0.424	S	S	.	.			trans	-66.9	154.7	179.1	68.8	0	0	0	0	111.6	R523 E524 W525	S521-R523 PolarHBondContact O-N 3.36Å; S521-E524 PolarHBondContact N-OE2 3.39Å; S521-E524 PolarHBondContact O-N 2.92Å; S521-E524 VanDerWaalsContact O-N 3.14Å; S521-E524 PolarHBondContact OG-OE2 3.48Å; S521-W525 PolarHBondContact O-N 2.89Å
522	H	44.7	Very low	50.7	Low	73 Å²	73	86.2 Å²	86.2	34%	0.338	45%	0.449	S	S	.	.	H	α-helix	trans	-56	-19.1	-175.9	-142.7	-75.7	0	0	0	114.3
523	R	41.5	Very low	48.5	Very low	224 Å²	224	89.4 Å²	89.4	85%	0.845	48%	0.482	S	S	*	.	H	α-helix	trans	-85.9	-40.9	179.4	-88.7	-178.7	166.9	179	-3.7	113.6	S521 W525	S521-R523 PolarHBondContact O-N 3.36Å; R523-W525 VanDerWaalsContact C-N 3.34Å
524	E	46.4	Very low	46.5	Very low	111 Å²	111	92.6 Å²	92.6	52%	0.519	50%	0.5	S	S	.	.	H	α-helix	trans	-71.6	-34.5	179.6	-69.4	163	151.7	0	0	110.8	S521 G526 Q527 E528	S521-E524 PolarHBondContact N-OE2 3.39Å; S521-E524 PolarHBondContact O-N 2.92Å; S521-E524 VanDerWaalsContact O-N 3.14Å; S521-E524 PolarHBondContact OG-OE2 3.48Å; E524-G526 PolarHBondContact O-N 3.11Å; E524-Q527 PolarHBondContact O-N 2.97Å; E524-E528 PolarHBondContact O-N 3.3Å
525	W	49.4	Very low	45.2	Very low	12 Å²	12	97.2 Å²	97.2	5%	0.045	50%	0.501	C	S	.	.	H	α-helix	trans	-62.5	-41.1	177.5	-169.1	-105.8	0	0	0	114.1	F313 I510 S521 R523 Q527 E528 M529	F313-W525 AromaticContact CE1-CD1 3.98Å; F313-W525 AromaticContact CE1-NE1 3.42Å; F313-W525 AromaticContact CE2-CD1 3.98Å; F313-W525 AromaticContact CZ-CD1 3.26Å; F313-W525 HydrophobicContact CZ-CG 4.33Å; F313-W525 AromaticContact CZ-NE1 3.2Å; I510-W525 HydrophobicContact CD1-CZ2 4.43Å; S521-W525 PolarHBondContact O-N 2.89Å; R523-W525 VanDerWaalsContact C-N 3.34Å; W525-Q527 PolarHBondContact O-N 3.23Å; W525-E528 VanDerWaalsContact CZ3-OE2 3.24Å; W525-E528 WeakPolarHBondContact CZ3-OE2 3.26Å; W525-E528 PolarHBondContact O-N 3.03Å; W525-M529 WeakPolarHBondContact O-CG 2.99Å; W525-M529 PolarHBondContact O-N 3.29Å
526	G	50	Low	43.8	Very low	19 Å²	19	95.5 Å²	95.5	20%	0.196	52%	0.516	C	S	.	.	H	α-helix	trans	-60.6	-34.2	177	0	0	0	0	0	112.1	E524 V530	E524-G526 PolarHBondContact O-N 3.11Å; G526-V530 WeakPolarHBondContact O-CG2 2.89Å; G526-V530 PolarHBondContact O-N 2.98Å; G526-V530 VanDerWaalsContact O-N 3.13Å
527	Q	44.4	Very low	42.9	Very low	150 Å²	150	97.7 Å²	97.7	70%	0.701	53%	0.528	S	S	*	.	H	α-helix	trans	-75.9	-38.4	179.2	-70.1	-179.5	-21.9	0	0	112.6	E524 W525 M529 V530 G531	E524-Q527 PolarHBondContact O-N 2.97Å; W525-Q527 PolarHBondContact O-N 3.23Å; Q527-M529 VanDerWaalsContact C-N 3.3Å; Q527-M529 PolarHBondContact O-N 3.39Å; Q527-V530 PolarHBondContact O-N 2.9Å; Q527-G531 PolarHBondContact O-N 3.08Å
528	E	51.6	Low	41.6	Very low	111 Å²	111	96.8 Å²	96.8	52%	0.519	54%	0.54	S	S	.	.	H	α-helix	trans	-62.4	-37.6	173.5	-76	-168.5	149	0	0	112.6	E524 W525 R532	E524-E528 PolarHBondContact O-N 3.3Å; W525-E528 VanDerWaalsContact CZ3-OE2 3.24Å; W525-E528 WeakPolarHBondContact CZ3-OE2 3.26Å; W525-E528 PolarHBondContact O-N 3.03Å; E528-R532 PolarHBondContact O-N 2.91Å
529	M	44.9	Very low	40.6	Very low	57 Å²	57	101.4 Å²	101.4	28%	0.281	57%	0.571	S	S	.	*	H	α-helix	trans	-71.7	-36.8	178.6	-70.3	-93.4	-87.3	0	0	112.2	H312 I510 W525 Q527	H312-M529 HydrophobicContact CB-CE 3.73Å; H312-M529 WeakPolarHBondContact O-CE 3.43Å; I510-M529 HydrophobicContact CD1-SD 4.39Å; W525-M529 WeakPolarHBondContact O-CG 2.99Å; W525-M529 PolarHBondContact O-N 3.29Å; Q527-M529 VanDerWaalsContact C-N 3.3Å; Q527-M529 PolarHBondContact O-N 3.39Å
530	V	44.8	Very low	39.7	Very low	88 Å²	88	99.8 Å²	99.8	53%	0.533	57%	0.573	S	S	.	*	H	α-helix	trans	-76.2	-38.4	176.8	173	0	0	0	0	111.3	G526 Q527 R532 G533	G526-V530 WeakPolarHBondContact O-CG2 2.89Å; G526-V530 PolarHBondContact O-N 2.98Å; G526-V530 VanDerWaalsContact O-N 3.13Å; Q527-V530 PolarHBondContact O-N 2.9Å; V530-R532 VanDerWaalsContact C-N 3.26Å; V530-R532 PolarHBondContact O-N 2.02Å; V530-G533 PolarHBondContact O-N 3.08Å; V530-G533 VanDerWaalsContact O-N 3.15Å
531	G	38.3	Very low	39.2	Very low	42 Å²	42	109.8 Å²	109.8	43%	0.433	61%	0.606	S	S	.	*	H	α-helix	trans	-63.2	-27.3	179.3	0	0	0	0	0	114.1	Q527	Q527-G531 PolarHBondContact O-N 3.08Å
532	R	45.5	Very low	38.2	Very low	207 Å²	207	113.2 Å²	113.2	78%	0.781	63%	0.63	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.9	-9.4	176.5	-74.4	-171.3	-179.5	-155.5	1.7	114.9	E528 V530 M534	E528-R532 PolarHBondContact O-N 2.91Å; V530-R532 VanDerWaalsContact C-N 3.26Å; V530-R532 PolarHBondContact O-N 2.02Å; R532-M534 VanDerWaalsContact C-N 3.29Å
533	G	31.2	Very low	37.4	Very low	70 Å²	70	117.7 Å²	117.7	72%	0.722	66%	0.656	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76.8	-13.6	171.9	0	0	0	0	0	114	V530	V530-G533 PolarHBondContact O-N 3.08Å; V530-G533 VanDerWaalsContact O-N 3.15Å
534	M	33.3	Very low	36.9	Very low	163 Å²	163	112.5 Å²	112.5	80%	0.803	65%	0.654	S	S	*	*	S	Bend	trans	-120.9	6.8	-172	-116	155.5	71.2	0	0	115.1	R532	R532-M534 VanDerWaalsContact C-N 3.29Å
535	H	33.3	Very low	36	Very low	175 Å²	175	110.7 Å²	110.7	81%	0.81	67%	0.666	S	S	*	*			trans	-119.8	60.5	173.1	-78.5	-20.4	0	0	0	111.8
536	G	32.6	Very low	35	Very low	70 Å²	70	116 Å²	116	72%	0.722	71%	0.705	S	S	*	*	S	Bend	trans	-110	120.8	148.5	0	0	0	0	0	107.8
537	A	31.7	Very low	34.1	Very low	108 Å²	108	124.4 Å²	124.4	89%	0.893	74%	0.739	S	S	*	*	S	Bend	trans	88.1	122.5	179.4	0	0	0	0	0	117
538	G	27.2	Very low	33.4	Very low	68 Å²	68	130.1 Å²	130.1	70%	0.701	77%	0.765	S	S	*	*			trans	108.1	82.4	158.1	0	0	0	0	0	115.5	T540	G538-T540 PolarHBondContact O-N 2.88Å
539	V	29.5	Very low	32.5	Very low	144 Å²	144	131.1 Å²	131.1	87%	0.873	78%	0.778	S	S	*	*			trans	-66.4	107.2	154.1	172.7	0	0	0	0	107.2
540	T	25.7	Very low	31.9	Very low	132 Å²	132	134.9 Å²	134.9	81%	0.81	80%	0.804	S	S	*	*			trans	-108.6	105.9	164.2	31.1	0	0	0	0	109.1	G538 S542	G538-T540 PolarHBondContact O-N 2.88Å; T540-S542 PolarHBondContact O-N 3.44Å
541	R	30	Very low	31.2	Very low	239 Å²	239	137.6 Å²	137.6	90%	0.902	82%	0.819	S	S	*	*			trans	-61.9	119.9	161.7	-83.6	176.8	166.4	171.6	-5.3	108.5
542	S	26.9	Very low	30.7	Very low	115 Å²	115	143.2 Å²	143.2	80%	0.804	84%	0.842	S	S	*	*			trans	-102.5	106	162.2	58.2	0	0	0	0	109.3	T540	T540-S542 PolarHBondContact O-N 3.44Å
543	N	28.1	Very low	29.8	Very low	167 Å²	167	139.2 Å²	139.2	89%	0.893	85%	0.845	S	S	*	*			trans	-72.6	131.1	161.7	-106.6	0.1	0	0	0	109.3
544	S	31	Very low	29.7	Very low	114 Å²	114	143.8 Å²	143.8	80%	0.797	85%	0.854	S	S	*	*			trans	-164.3	110.4	149.6	54.9	0	0	0	0	105.8
545	G	26.4	Very low	29.5	Very low	74 Å²	74	142.4 Å²	142.4	76%	0.763	86%	0.857	S	S	*	*			cis	90.5	79.6	44.8	0	0	0	0	0	107.5
546	S	29.2	Very low	29.2	Very low	124 Å²	124	139.9 Å²	139.9	87%	0.867	86%	0.861	S	S	*	*			trans	-59	127.6	171.8	43.5	0	0	0	0	110.7
547	Q	29.7	Very low	28.9	Very low	194 Å²	194	145.8 Å²	145.8	91%	0.907	87%	0.873	S	S	*	*			trans	-81.9	152.5	159.5	-81.3	-179.8	-27.7	0	0	109.7
548	E	31.6	Very low	28.7	Very low	270 Å²	270	149.2 Å²	149.2	100%	1.262	87%	0.871	S	S	*	*			trans	-45.8	0	-176.5	-62.9	173.6	141.3	0	0	116.6

Retrieved 548 of 548 residues in 404.5 ms (Link to these results)

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