A0A096MQH3_PAPAN Loading...

MAP kinase-activated protein kinase 5

AlphaFold DB (H9G146), UniProt , Accession A0A096MQH3, Species PAPAN (Papio anubis, Olive baboon), Gene MAPKAPK5, Length 473 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M38.3Very low60.8Low206 Ų206100.2 Ų100.2100%1.01552%0.521SS*.  0-42.50-81.5-178.257.700112.6S5M1-S5 PolarHBondContact O-N 3.5Å
2S49.7Very low63.6Low86 Ų8697.4 Ų97.460%0.60150%0.502SS*.Hα-helixtrans-66.6-48.6176.248.70000113.5E4 S5 D6S2-E4 VanDerWaalsContact C-N 3.32Å; S2-E4 PolarHBondContact O-N 2.95Å; S2-S5 WeakPolarHBondContact O-CB 3.4Å; S2-S5 PolarHBondContact O-N 3.09Å; S2-D6 PolarHBondContact O-N 3.34Å; S2-D6 VanDerWaalsContact O-N 3.09Å
3E51.7Low65.8Low142 Ų142103.2 Ų103.266%0.66453%0.525SS*.Hα-helixtrans-63.5-33.9-179-67.7179.2172.900113.5D6 M7E3-D6 PolarHBondContact O-N 3.35Å; E3-M7 WeakPolarHBondContact O-CB 3.44Å; E3-M7 WeakPolarHBondContact O-CG 3.47Å; E3-M7 PolarHBondContact O-N 3.09Å
4E51.6Low67.8Low130 Ų130100.5 Ų100.561%0.60752%0.516SS*.Hα-helixtrans-69.6-36.3178-142.7166.2-162.200111S2 E8S2-E4 VanDerWaalsContact C-N 3.32Å; S2-E4 PolarHBondContact O-N 2.95Å; E4-E8 PolarHBondContact O-N 3.49Å
5S54.2Low69.6Low49 Ų4996.7 Ų96.734%0.34350%0.502SS..Hα-helixtrans-68.1-39.1175.2125.40000112.7M1 S2 M7 K9M1-S5 PolarHBondContact O-N 3.5Å; S2-S5 WeakPolarHBondContact O-CB 3.4Å; S2-S5 PolarHBondContact O-N 3.09Å; S5-M7 VanDerWaalsContact C-N 3.32Å; S5-K9 WeakPolarHBondContact O-CG 3.23Å; S5-K9 PolarHBondContact O-N 2.6Å; S5-K9 PolarHBondContact OG-NZ 3.17Å
6D59.7Low71.2Confident91 Ų9190.8 Ų90.849%0.48747%0.471SS..Hα-helixtrans-76.3-24.7-178.2-65.1-25.8000112.2S2 E3 K9 A10S2-D6 PolarHBondContact O-N 3.34Å; S2-D6 VanDerWaalsContact O-N 3.09Å; E3-D6 PolarHBondContact O-N 3.35Å; D6-K9 PolarHBondContact O-N 3.06Å; D6-K9 IonicContact OD1-NZ 2.63Å; D6-K9 PolarHBondContact OD1-NZ 2.89Å; D6-A10 PolarHBondContact O-N 3.38Å
7M63.3Low72.5Confident44 Ų4490.7 Ų90.722%0.21747%0.471CS..Hα-helixtrans-77.1-36.3174.7-70.4-74.1-82.800113.1E3 S5 K9 A10 R64 M67E3-M7 WeakPolarHBondContact O-CB 3.44Å; E3-M7 WeakPolarHBondContact O-CG 3.47Å; E3-M7 PolarHBondContact O-N 3.09Å; S5-M7 VanDerWaalsContact C-N 3.32Å; M7-K9 PolarHBondContact O-N 2.77Å; M7-A10 WeakPolarHBondContact O-CB 3.31Å; M7-A10 PolarHBondContact O-N 2.79Å; M7-A10 VanDerWaalsContact O-N 3.13Å; M7-R64 HydrophobicContact CE-CB 3.99Å; M7-R64 HydrophobicContact CE-CG 3.55Å; M7-M67 HydrophobicContact CE-CB 3.76Å; M7-M67 HydrophobicContact CE-CE 3.16Å; M7-M67 HydrophobicContact CE-CG 4.4Å; M7-M67 HydrophobicContact CE-SD 4.07Å; M7-M67 HydrophobicContact SD-CE 3.82Å; M7-M67 HydrophobicContact SD-SD 4.34Å
8E63.3Low73.8Confident130 Ų13092.5 Ų92.561%0.60748%0.477SS*.Hα-helixtrans-63.3-34.5170.3-76.6-168.6151.300111.5E4 A10 I11E4-E8 PolarHBondContact O-N 3.49Å; E8-A10 VanDerWaalsContact C-N 3.26Å; E8-A10 PolarHBondContact O-N 3.25Å; E8-I11 PolarHBondContact O-N 3.43Å
9K63.6Low74.9Confident149 Ų14990.4 Ų90.465%0.64847%0.465SS*.Hα-helixtrans-67.9-23.1172.9-66.8172.2-162.5156.30113.7S5 D6 M7 I11S5-K9 WeakPolarHBondContact O-CG 3.23Å; S5-K9 PolarHBondContact O-N 2.6Å; S5-K9 PolarHBondContact OG-NZ 3.17Å; D6-K9 PolarHBondContact O-N 3.06Å; D6-K9 IonicContact OD1-NZ 2.63Å; D6-K9 PolarHBondContact OD1-NZ 2.89Å; M7-K9 PolarHBondContact O-N 2.77Å; K9-I11 VanDerWaalsContact C-N 3.31Å
10A81.4Confident76Confident50 Ų5085.9 Ų85.941%0.41344%0.442SS..Hα-helixtrans-78.4-15.2178.400000113.1D6 M7 E8D6-A10 PolarHBondContact O-N 3.38Å; M7-A10 WeakPolarHBondContact O-CB 3.31Å; M7-A10 PolarHBondContact O-N 2.79Å; M7-A10 VanDerWaalsContact O-N 3.13Å; E8-A10 VanDerWaalsContact C-N 3.26Å; E8-A10 PolarHBondContact O-N 3.25Å
11I92.2Very high77Confident25 Ų2584.8 Ų84.813%0.12844%0.442CS..EExtended strand (participates in β ladder)trans-88.1118.2177.7-58.9175.4000109E8 K9 V81 A83E8-I11 PolarHBondContact O-N 3.43Å; K9-I11 VanDerWaalsContact C-N 3.31Å; I11-V81 HydrophobicContact CG1-CB 4.42Å; I11-V81 HydrophobicContact CG1-CG1 4.16Å; I11-V81 HydrophobicContact CG2-CG1 4.32Å; I11-A83 HydrophobicContact CG2-CB 3.57Å
12K94.3Very high79.6Confident67 Ų6776.1 Ų76.129%0.29140%0.399SS..EExtended strand (participates in β ladder)trans-77.4132.8178.2-67-179.2167.2-166.70111.4E19 E80 V81 F82 A83K12-E19 VanDerWaalsContact NZ-CD 3.31Å; K12-E19 IonicContact NZ-OE1 2.6Å; K12-E19 PolarHBondContact NZ-OE1 3.13Å; K12-E19 IonicContact NZ-OE2 2.89Å; K12-E19 PolarHBondContact NZ-OE2 3.27Å; K12-E80 VanDerWaalsContact CE-OE1 3.23Å; K12-E80 WeakPolarHBondContact CE-OE1 3.49Å; K12-E80 IonicContact NZ-OE1 3.43Å; K12-E80 PolarHBondContact NZ-OE1 3Å; K12-V81 PolarHBondContact N-O 2.85Å; K12-F82 HydrophobicContact CB-CD1 3.54Å; K12-F82 HydrophobicContact CB-CE1 3.87Å; K12-F82 HydrophobicContact CB-CG 4.14Å; K12-F82 HydrophobicContact CD-CD1 3.95Å; K12-F82 HydrophobicContact CD-CE1 3.37Å; K12-F82 HydrophobicContact CD-CE2 4.45Å; K12-F82 HydrophobicContact CD-CZ 3.65Å; K12-F82 HydrophobicContact CG-CD1 4.39Å; K12-F82 HydrophobicContact CG-CE1 4.27Å; K12-F82 CarbonylContact O-C 3.49Å; K12-F82 VanDerWaalsContact O-CA 3.23Å; K12-F82 WeakPolarHBondContact O-CA 3.44Å; K12-A83 PolarHBondContact O-N 3.19Å
13E92.6Very high81.5Confident172 Ų17274.7 Ų74.780%0.80439%0.385SS*.  trans-93.7-12.7172.1-62.3-169.7163.700112.9N84E13-N84 PolarHBondContact O-ND2 3.39Å
14T93.8Very high83.1Confident66 Ų6671.9 Ų71.941%0.40537%0.368SS..SBendtrans-60.4154.3172.952.40000110.9I16 N84T14-I16 PolarHBondContact O-N 3.45Å; T14-N84 PolarHBondContact O-ND2 3.49Å; T14-N84 PolarHBondContact O-OD1 3.35Å
15S93.8Very high84.5Confident43 Ų4371.6 Ų71.630%0.30138%0.376SS..  trans-67.2124.2179.6-179.30000110L17 E18S15-L17 PolarHBondContact O-N 3.33Å; S15-L17 PolarHBondContact OG-N 2.81Å; S15-E18 WeakPolarHBondContact CB-OE1 3.46Å; S15-E18 PolarHBondContact N-OE1 3.17Å; S15-E18 VanDerWaalsContact O-CB 3.31Å; S15-E18 WeakPolarHBondContact O-CB 3.36Å; S15-E18 PolarHBondContact O-N 3.28Å
16I95.1Very high85.9Confident2 Ų273.1 Ų73.11%0.0138%0.377CS..Hα-helixtrans-53.6-29.1173-169166.7000111.8T14 E18 E19 Y20 I22 L50 F82 N84 L99 V101T14-I16 PolarHBondContact O-N 3.45Å; I16-E18 PolarHBondContact O-N 3.42Å; I16-E19 PolarHBondContact O-N 3.33Å; I16-E19 VanDerWaalsContact O-N 3.17Å; I16-Y20 HydrophobicContact CG1-CD2 4Å; I16-Y20 HydrophobicContact CG1-CG 4.35Å; I16-Y20 PolarHBondContact O-N 2.81Å; I16-I22 HydrophobicContact CD1-CD1 4.5Å; I16-I22 HydrophobicContact CG2-CD1 3.86Å; I16-L50 HydrophobicContact CD1-CD1 3.71Å; I16-L50 HydrophobicContact CD1-CD2 4.26Å; I16-F82 HydrophobicContact CB-CB 4.31Å; I16-F82 HydrophobicContact CB-CD1 4.06Å; I16-F82 HydrophobicContact CB-CD2 4.17Å; I16-F82 HydrophobicContact CB-CE1 4.43Å; I16-F82 HydrophobicContact CB-CG 3.93Å; I16-F82 HydrophobicContact CD1-CD2 3.76Å; I16-F82 HydrophobicContact CD1-CE2 4.11Å; I16-F82 HydrophobicContact CD1-CG 4.32Å; I16-F82 HydrophobicContact CG1-CD1 4.46Å; I16-F82 HydrophobicContact CG1-CD2 3.84Å; I16-F82 HydrophobicContact CG1-CE2 3.93Å; I16-F82 HydrophobicContact CG1-CG 4.14Å; I16-F82 HydrophobicContact CG1-CZ 4.28Å; I16-N84 PolarHBondContact N-OD1 2.96Å; I16-L99 HydrophobicContact CB-CD1 4Å; I16-L99 HydrophobicContact CD1-CB 3.95Å; I16-L99 HydrophobicContact CD1-CD1 4.12Å; I16-L99 HydrophobicContact CG2-CD1 3.52Å; I16-V101 HydrophobicContact CD1-CG2 3.98Å
17L93.9Very high87Confident90 Ų9074.5 Ų74.547%0.47138%0.379SS..Hα-helixtrans-71.1-11.9-178.5-61.2178.9000112.5S15 I22 K42S15-L17 PolarHBondContact O-N 3.33Å; S15-L17 PolarHBondContact OG-N 2.81Å; L17-I22 HydrophobicContact CD2-CD1 3.73Å; L17-I22 HydrophobicContact CD2-CG1 4.13Å; L17-K42 WeakPolarHBondContact O-CE 3.39Å; L17-K42 PolarHBondContact O-NZ 3.04Å
18E95.2Very high87.9Confident123 Ų12376 Ų7658%0.57539%0.388SS*.Hα-helixtrans-70.4-43.6170.4-68.6165.9-146.100109.9S15 I16 K42S15-E18 WeakPolarHBondContact CB-OE1 3.46Å; S15-E18 PolarHBondContact N-OE1 3.17Å; S15-E18 VanDerWaalsContact O-CB 3.31Å; S15-E18 WeakPolarHBondContact O-CB 3.36Å; S15-E18 PolarHBondContact O-N 3.28Å; I16-E18 PolarHBondContact O-N 3.42Å; E18-K42 WeakPolarHBondContact O-CD 3.09Å; E18-K42 PolarHBondContact O-NZ 3.24Å; E18-K42 VanDerWaalsContact O-NZ 3.09Å
19E96.5Very high88.2Confident52 Ų5271.2 Ų71.224%0.24337%0.373CS..Hα-helixtrans-97.9-27.6-172.4-62.3-174.3-124.400114.1K12 I16 K42K12-E19 VanDerWaalsContact NZ-CD 3.31Å; K12-E19 IonicContact NZ-OE1 2.6Å; K12-E19 PolarHBondContact NZ-OE1 3.13Å; K12-E19 IonicContact NZ-OE2 2.89Å; K12-E19 PolarHBondContact NZ-OE2 3.27Å; I16-E19 PolarHBondContact O-N 3.33Å; I16-E19 VanDerWaalsContact O-N 3.17Å; E19-K42 WeakPolarHBondContact O-CG 3.45Å; E19-K42 PolarHBondContact O-N 3.38Å
20Y96.9Very high88Confident1 Ų167.3 Ų67.30%0.00437%0.368CS..EExtended strand (participates in β ladder)trans-128.5144.7-172.9-68.2-95.4000112.9I16 C39 V40 K41 F48 E80 F82 V101I16-Y20 HydrophobicContact CG1-CD2 4Å; I16-Y20 HydrophobicContact CG1-CG 4.35Å; I16-Y20 PolarHBondContact O-N 2.81Å; Y20-C39 HydrophobicContact CD1-CB 4.4Å; Y20-V40 CarbonylContact C-O 3.56Å; Y20-V40 WeakPolarHBondContact CA-O 3.39Å; Y20-K41 HydrophobicContact CD1-CB 3.92Å; Y20-K41 HydrophobicContact CD1-CG 4.42Å; Y20-K41 HydrophobicContact CE1-CB 3.53Å; Y20-K41 HydrophobicContact CE1-CD 4.22Å; Y20-K41 HydrophobicContact CE1-CG 3.9Å; Y20-F48 HydrophobicContact CD1-CD2 4.45Å; Y20-F48 AromaticContact CE1-CD2 3.73Å; Y20-F48 HydrophobicContact CE1-CD2 3.73Å; Y20-F48 HydrophobicContact CE1-CE2 4.16Å; Y20-F48 HydrophobicContact CE1-CG 4.36Å; Y20-E80 PolarHBondContact OH-OE2 3.45Å; Y20-F82 HydrophobicContact CD2-CE2 4.31Å; Y20-F82 HydrophobicContact CD2-CZ 4.21Å; Y20-F82 HydrophobicContact CE2-CE2 4.05Å; Y20-F82 AromaticContact CE2-CZ 3.98Å; Y20-F82 HydrophobicContact CE2-CZ 3.98Å; Y20-V101 HydrophobicContact CE1-CG1 3.83Å; Y20-V101 HydrophobicContact CE1-CG2 4.47Å; Y20-V101 HydrophobicContact CE2-CG2 4.31Å
21S95.7Very high86.8Confident63 Ų6366.9 Ų66.944%0.44137%0.369SS..EExtended strand (participates in β ladder)trans-97.4123166.7-64.50000109.3C39 V40S21-C39 CarbonylContact O-C 3.56Å; S21-C39 VanDerWaalsContact O-CA 3.23Å; S21-C39 WeakPolarHBondContact O-CA 3.42Å; S21-V40 PolarHBondContact N-O 2.86Å; S21-V40 PolarHBondContact O-N 2.87Å
22I92.8Very high84.9Confident23 Ų2372 Ų7212%0.11840%0.395CS..EExtended strand (participates in β ladder)trans-102.1128-175.3-56.2172.6000110.2I16 L17 W24 C39 L50I16-I22 HydrophobicContact CD1-CD1 4.5Å; I16-I22 HydrophobicContact CG2-CD1 3.86Å; L17-I22 HydrophobicContact CD2-CD1 3.73Å; L17-I22 HydrophobicContact CD2-CG1 4.13Å; I22-W24 HydrophobicContact CB-CD2 4.48Å; I22-W24 HydrophobicContact CB-CZ2 4.02Å; I22-W24 HydrophobicContact CD1-CH2 4.03Å; I22-W24 HydrophobicContact CD1-CZ2 3.6Å; I22-W24 HydrophobicContact CG1-CZ2 4.41Å; I22-W24 HydrophobicContact CG2-CD2 3.8Å; I22-W24 HydrophobicContact CG2-CE3 4.14Å; I22-W24 HydrophobicContact CG2-CG 4.3Å; I22-W24 HydrophobicContact CG2-CH2 4.11Å; I22-W24 HydrophobicContact CG2-CZ2 3.8Å; I22-W24 HydrophobicContact CG2-CZ3 4.29Å; I22-W24 PolarHBondContact O-N 2.87Å; I22-C39 HydrophobicContact CG1-CB 4.25Å; I22-L50 HydrophobicContact CB-CD2 4.49Å; I22-L50 HydrophobicContact CD1-CD2 3.57Å; I22-L50 HydrophobicContact CG1-CD2 3.82Å; I22-L50 HydrophobicContact CG2-CD2 3.86Å
23N90Very high83.4Confident57 Ų5770 Ų7031%0.30539%0.389SS..EExtended strand (participates in β ladder)trans-87.696.9170.9-171-24000110.2T25 Q26 V38N23-T25 VanDerWaalsContact C-N 3.3Å; N23-T25 PolarHBondContact O-N 2.86Å; N23-T25 PolarHBondContact OD1-N 2.53Å; N23-T25 VanDerWaalsContact OD1-N 3.14Å; N23-T25 PolarHBondContact OD1-OG1 2.62Å; N23-Q26 HydrophobicContact CB-CB 4.31Å; N23-Q26 WeakPolarHBondContact ND2-CB 3.31Å; N23-Q26 PolarHBondContact ND2-OE1 2.79Å; N23-Q26 PolarHBondContact OD1-N 3Å; N23-V38 HydrophobicContact CB-CB 4.32Å; N23-V38 WeakPolarHBondContact CB-O 3.35Å; N23-V38 PolarHBondContact N-O 3.29Å
24W84.6Confident82.5Confident82 Ų8262.4 Ų62.431%0.31136%0.357SS..EExtended strand (participates in β ladder)trans-74.6-14-178.2-63.3105.6000114.6I22 R37 I52 V86 F88I22-W24 HydrophobicContact CB-CD2 4.48Å; I22-W24 HydrophobicContact CB-CZ2 4.02Å; I22-W24 HydrophobicContact CD1-CH2 4.03Å; I22-W24 HydrophobicContact CD1-CZ2 3.6Å; I22-W24 HydrophobicContact CG1-CZ2 4.41Å; I22-W24 HydrophobicContact CG2-CD2 3.8Å; I22-W24 HydrophobicContact CG2-CE3 4.14Å; I22-W24 HydrophobicContact CG2-CG 4.3Å; I22-W24 HydrophobicContact CG2-CH2 4.11Å; I22-W24 HydrophobicContact CG2-CZ2 3.8Å; I22-W24 HydrophobicContact CG2-CZ3 4.29Å; I22-W24 PolarHBondContact O-N 2.87Å; W24-R37 PolarHBondContact O-NH1 3.02Å; W24-R37 PolarHBondContact O-NH2 3.43Å; W24-I52 HydrophobicContact CH2-CD1 4.19Å; W24-I52 HydrophobicContact CZ3-CD1 3.72Å; W24-V86 HydrophobicContact CH2-CG1 3.78Å; W24-V86 HydrophobicContact CZ2-CG1 4.21Å; W24-F88 HydrophobicContact CZ3-CE1 4.12Å; W24-F88 HydrophobicContact CZ3-CE2 4.46Å; W24-F88 HydrophobicContact CZ3-CZ 4.03Å
25T82.7Confident82.2Confident125 Ų12561.1 Ų61.177%0.76735%0.35SS*.EExtended strand (participates in β ladder)trans-92.7-41.1-179.959.60000110.8N23 K27 R37N23-T25 VanDerWaalsContact C-N 3.3Å; N23-T25 PolarHBondContact O-N 2.86Å; N23-T25 PolarHBondContact OD1-N 2.53Å; N23-T25 VanDerWaalsContact OD1-N 3.14Å; N23-T25 PolarHBondContact OD1-OG1 2.62Å; T25-K27 PolarHBondContact O-N 2.84Å; T25-R37 VanDerWaalsContact C-NH1 3.33Å; T25-R37 PolarHBondContact O-NH1 3.34Å
26Q83.2Confident82Confident81 Ų8160.3 Ų60.338%0.37934%0.343SS..EExtended strand (participates in β ladder)trans-75.3113.1179.6-170.11742.600111.4N23 R37 V38N23-Q26 HydrophobicContact CB-CB 4.31Å; N23-Q26 WeakPolarHBondContact ND2-CB 3.31Å; N23-Q26 PolarHBondContact ND2-OE1 2.79Å; N23-Q26 PolarHBondContact OD1-N 3Å; Q26-R37 WeakPolarHBondContact O-CD 3.49Å; Q26-R37 PolarHBondContact O-NH1 3.36Å; Q26-V38 HydrophobicContact CG-CG2 4.05Å
27K83.3Confident81.8Confident119 Ų11962 Ų6252%0.51735%0.349SS..EExtended strand (participates in β ladder)trans-100.2125.2176.2-169.8178.5179.5-175.70109T25 G29T25-K27 PolarHBondContact O-N 2.84Å; K27-G29 WeakPolarHBondContact CE-O 3.33Å; K27-G29 WeakPolarHBondContact CG-O 3.24Å
28L81.2Confident81.9Confident77 Ų7757.9 Ų57.940%0.40333%0.328SS..EExtended strand (participates in β ladder)trans-84.8-34.4174-65.9178.3000111.3V36 V38 A49 M104L28-V36 HydrophobicContact CB-CB 4.37Å; L28-V36 HydrophobicContact CB-CG1 4.16Å; L28-V36 HydrophobicContact CD1-CG1 4.24Å; L28-V36 PolarHBondContact N-O 3.37Å; L28-V38 HydrophobicContact CD1-CG2 3.81Å; L28-V38 HydrophobicContact CD2-CG2 3.57Å; L28-V38 HydrophobicContact CG-CG2 3.7Å; L28-A49 HydrophobicContact CD1-CB 4.08Å; L28-M104 HydrophobicContact CD1-CE 3.9Å; L28-M104 HydrophobicContact CD1-SD 3.84Å; L28-M104 HydrophobicContact CD2-CE 4.31Å
29G70.2Confident81.9Confident29 Ų2952.1 Ų52.130%0.29930%0.301SS..EExtended strand (participates in β ladder)trans-167.3163.8177.700000112.6K27 V36K27-G29 WeakPolarHBondContact CE-O 3.33Å; K27-G29 WeakPolarHBondContact CG-O 3.24Å; G29-V36 PolarHBondContact O-N 2.93Å
30A59.2Low81.9Confident66 Ų6651.3 Ų51.355%0.54530%0.3SS..EExtended strand (participates in β ladder)trans-130.298.1161.600000108.6
31G55.1Low81.9Confident41 Ų4153.5 Ų53.542%0.42331%0.309SS..  trans-85.7173166.600000111.4S33 G34G31-S33 PolarHBondContact O-N 3.17Å; G31-G34 PolarHBondContact O-N 3.26Å
32I53.1Low82Confident134 Ų13454.8 Ų54.869%0.68731%0.307SS*.SBendtrans-57.1-28.3170.8-64.8165.3000111.1F172I32-F172 HydrophobicContact CD1-CZ 4.45Å; I32-F172 HydrophobicContact CG2-CE2 4.36Å; I32-F172 HydrophobicContact CG2-CZ 4.03Å
33S62.5Low82.2Confident24 Ų2458.4 Ų58.417%0.16833%0.334CS..SBendtrans-75.5-35.5-176.4-43.60000111.8G31 K51 L53 D169G31-S33 PolarHBondContact O-N 3.17Å; S33-K51 VanDerWaalsContact CB-CE 3.45Å; S33-L53 WeakPolarHBondContact O-CD2 3.05Å; S33-D169 WeakPolarHBondContact CB-OD1 3.39Å; S33-D169 VanDerWaalsContact OG-CG 3.28Å; S33-D169 PolarHBondContact OG-OD1 3.29Å; S33-D169 PolarHBondContact OG-OD2 3.37Å
34G73.9Confident82.5Confident13 Ų1359.5 Ų59.513%0.13434%0.343CS..  trans155.6171.1178.600000113G31G31-G34 PolarHBondContact O-N 3.26Å
35P86.9Confident83.1Confident38 Ų3862.1 Ų62.125%0.24736%0.359CS..EExtended strand (participates in β ladder)trans-69.1142.7177.428.6-34.1000111.7I52 F88P35-I52 WeakPolarHBondContact CD-O 3.48Å; P35-I52 HydrophobicContact CG-CB 4.39Å; P35-I52 PolarHBondContact O-N 2.9Å; P35-I52 VanDerWaalsContact O-N 3.13Å; P35-F88 HydrophobicContact CG-CE1 4.03Å; P35-F88 HydrophobicContact CG-CZ 4.04Å
36V90.1Very high83.8Confident27 Ų2761.3 Ų61.316%0.16435%0.347CS..EExtended strand (participates in β ladder)trans-114.9131.5173.1-171.50000109.8L28 G29 A49 L50 K51L28-V36 HydrophobicContact CB-CB 4.37Å; L28-V36 HydrophobicContact CB-CG1 4.16Å; L28-V36 HydrophobicContact CD1-CG1 4.24Å; L28-V36 PolarHBondContact N-O 3.37Å; G29-V36 PolarHBondContact O-N 2.93Å; V36-A49 HydrophobicContact CG1-CB 4.21Å; V36-L50 CarbonylContact C-O 3.51Å; V36-L50 VanDerWaalsContact CA-O 3.3Å; V36-L50 WeakPolarHBondContact CA-O 3.38Å; V36-K51 HydrophobicContact CG2-CB 4.26Å; V36-K51 HydrophobicContact CG2-CG 4.24Å
37R91.7Very high84.4Confident37 Ų3762.5 Ų62.514%0.1435%0.348CS..EExtended strand (participates in β ladder)trans-123.7162.8-176.1-61.1-61.8-171.8162.46.7111W24 T25 Q26 L50 I52W24-R37 PolarHBondContact O-NH1 3.02Å; W24-R37 PolarHBondContact O-NH2 3.43Å; T25-R37 VanDerWaalsContact C-NH1 3.33Å; T25-R37 PolarHBondContact O-NH1 3.34Å; Q26-R37 WeakPolarHBondContact O-CD 3.49Å; Q26-R37 PolarHBondContact O-NH1 3.36Å; R37-L50 HydrophobicContact CB-CB 4.47Å; R37-L50 PolarHBondContact N-O 2.71Å; R37-L50 PolarHBondContact O-N 2.97Å; R37-I52 HydrophobicContact CG-CD1 4.17Å
38V94.3Very high85Confident4 Ų457.3 Ų57.32%0.02433%0.325CS..EExtended strand (participates in β ladder)trans-82.5135.6166.4-179.30000108.6N23 Q26 L28 M104N23-V38 HydrophobicContact CB-CB 4.32Å; N23-V38 WeakPolarHBondContact CB-O 3.35Å; N23-V38 PolarHBondContact N-O 3.29Å; Q26-V38 HydrophobicContact CG-CG2 4.05Å; L28-V38 HydrophobicContact CD1-CG2 3.81Å; L28-V38 HydrophobicContact CD2-CG2 3.57Å; L28-V38 HydrophobicContact CG-CG2 3.7Å; V38-M104 HydrophobicContact CG2-CE 4.31Å
39C95.3Very high85.7Confident1 Ų154.1 Ų54.11%0.00731%0.309CS..EExtended strand (participates in β ladder)trans-127.2161.6162.865.80000110.8Y20 S21 I22 R47 F48 L50Y20-C39 HydrophobicContact CD1-CB 4.4Å; S21-C39 CarbonylContact O-C 3.56Å; S21-C39 VanDerWaalsContact O-CA 3.23Å; S21-C39 WeakPolarHBondContact O-CA 3.42Å; I22-C39 HydrophobicContact CG1-CB 4.25Å; C39-R47 WeakPolarHBondContact O-CA 3.11Å; C39-F48 PolarHBondContact N-O 3.32Å; C39-F48 PolarHBondContact O-N 2.92Å; C39-L50 HydrophobicContact CB-CB 4.23Å
40V97.3Very high86.8Confident36 Ų3652.7 Ų52.722%0.21830%0.295CS..EExtended strand (participates in β ladder)trans-128.7126-179.4-177.40000108.6Y20 S21 K42 Q45 E46 R47Y20-V40 CarbonylContact C-O 3.56Å; Y20-V40 WeakPolarHBondContact CA-O 3.39Å; S21-V40 PolarHBondContact N-O 2.86Å; S21-V40 PolarHBondContact O-N 2.87Å; V40-K42 PolarHBondContact O-N 3.47Å; V40-Q45 WeakPolarHBondContact CG1-O 3.23Å; V40-E46 CarbonylContact C-O 3.59Å; V40-E46 VanDerWaalsContact CA-O 3.3Å; V40-E46 WeakPolarHBondContact CA-O 3.32Å; V40-R47 HydrophobicContact CG2-CG 4.13Å
41K97.6Very high88.5Confident46 Ų4650 Ų5020%0.227%0.271CS..EExtended strand (participates in β ladder)trans-72.1124.6176-169.3167.8-168.9150.50109.1Y20 S43 T44 Q45 E46 F48 E80Y20-K41 HydrophobicContact CD1-CB 3.92Å; Y20-K41 HydrophobicContact CD1-CG 4.42Å; Y20-K41 HydrophobicContact CE1-CB 3.53Å; Y20-K41 HydrophobicContact CE1-CD 4.22Å; Y20-K41 HydrophobicContact CE1-CG 3.9Å; K41-S43 VanDerWaalsContact C-N 3.33Å; K41-S43 PolarHBondContact O-N 2.81Å; K41-T44 PolarHBondContact O-N 2.73Å; K41-Q45 VanDerWaalsContact O-CA 3.24Å; K41-Q45 WeakPolarHBondContact O-CA 3.44Å; K41-Q45 PolarHBondContact O-N 3.5Å; K41-E46 PolarHBondContact N-O 2.87Å; K41-F48 HydrophobicContact CB-CD2 4.13Å; K41-F48 HydrophobicContact CB-CE2 3.66Å; K41-F48 HydrophobicContact CD-CE2 4.38Å; K41-E80 IonicContact NZ-OE2 2.95Å; K41-E80 PolarHBondContact NZ-OE2 2.85Å
42K97.4Very high90.2Very high90 Ų9048.2 Ų48.239%0.39125%0.252SS..THydrogen-bonded Turntrans-65.4-35.7-171.3-67.3-177.4-170.4169.40113.2L17 E18 E19 V40 Q45L17-K42 WeakPolarHBondContact O-CE 3.39Å; L17-K42 PolarHBondContact O-NZ 3.04Å; E18-K42 WeakPolarHBondContact O-CD 3.09Å; E18-K42 PolarHBondContact O-NZ 3.24Å; E18-K42 VanDerWaalsContact O-NZ 3.09Å; E19-K42 WeakPolarHBondContact O-CG 3.45Å; E19-K42 PolarHBondContact O-N 3.38Å; V40-K42 PolarHBondContact O-N 3.47Å; K42-Q45 PolarHBondContact O-NE2 3.11Å
43S97.1Very high92Very high99 Ų9942.1 Ų42.169%0.69222%0.221SC*.THydrogen-bonded Turntrans-71.2-35.7-177.554.80000113.3K41K41-S43 VanDerWaalsContact C-N 3.33Å; K41-S43 PolarHBondContact O-N 2.81Å
44T96.8Very high93.4Very high81 Ų8143.8 Ų43.850%0.49723%0.227SC..THydrogen-bonded Turntrans-108.7-13.3-17561.20000113.8K41 E46K41-T44 PolarHBondContact O-N 2.73Å; T44-E46 PolarHBondContact O-N 2.77Å; T44-E46 VanDerWaalsContact O-N 3.17Å; T44-E46 VanDerWaalsContact OG1-CB 3.31Å; T44-E46 WeakPolarHBondContact OG1-CB 3.4Å; T44-E46 PolarHBondContact OG1-N 2.74Å
45Q96.6Very high94.3Very high136 Ų13644.9 Ų44.964%0.63623%0.23SC*.  trans58.915-169-59.3-62.9-56.400114.1V40 K41 K42V40-Q45 WeakPolarHBondContact CG1-O 3.23Å; K41-Q45 VanDerWaalsContact O-CA 3.24Å; K41-Q45 WeakPolarHBondContact O-CA 3.44Å; K41-Q45 PolarHBondContact O-N 3.5Å; K42-Q45 PolarHBondContact O-NE2 3.11Å
46E96.4Very high94.5Very high109 Ų10950.2 Ų50.251%0.50925%0.245SC..  trans-76.6142179.2-173.2178.1-176.500111.2V40 K41 T44 F48V40-E46 CarbonylContact C-O 3.59Å; V40-E46 VanDerWaalsContact CA-O 3.3Å; V40-E46 WeakPolarHBondContact CA-O 3.32Å; K41-E46 PolarHBondContact N-O 2.87Å; T44-E46 PolarHBondContact O-N 2.77Å; T44-E46 VanDerWaalsContact O-N 3.17Å; T44-E46 VanDerWaalsContact OG1-CB 3.31Å; T44-E46 WeakPolarHBondContact OG1-CB 3.4Å; T44-E46 PolarHBondContact OG1-N 2.74Å; E46-F48 HydrophobicContact CB-CE2 3.68Å; E46-F48 HydrophobicContact CB-CZ 3.96Å; E46-F48 HydrophobicContact CG-CE1 4.35Å; E46-F48 HydrophobicContact CG-CE2 3.76Å; E46-F48 HydrophobicContact CG-CZ 3.63Å; E46-F48 VanDerWaalsContact O-CD2 3.27Å; E46-F48 WeakPolarHBondContact O-CD2 3.42Å; E46-F48 WeakPolarHBondContact O-CE2 3.42Å; E46-F48 WeakPolarHBondContact OE2-CZ 3.39Å
47R95.9Very high94.4Very high106 Ų10654.2 Ų54.240%0.427%0.272SS..EExtended strand (participates in β ladder)trans-90.5136.5-177.4-6617366.2-141.7-6.3110.7C39 V40 M104 E106C39-R47 WeakPolarHBondContact O-CA 3.11Å; V40-R47 HydrophobicContact CG2-CG 4.13Å; R47-M104 VanDerWaalsContact C-CG 3.43Å; R47-M104 HydrophobicContact CB-CG 4.14Å; R47-M104 WeakPolarHBondContact O-CG 3.49Å; R47-E106 IonicContact CZ-OE1 3.29Å; R47-E106 IonicContact NH1-OE1 3.46Å; R47-E106 PolarHBondContact NH1-OE1 3.16Å; R47-E106 IonicContact NH2-OE1 2.75Å
48F96.7Very high94.1Very high10 Ų1059 Ų594%0.04429%0.293CS..EExtended strand (participates in β ladder)trans-133.8160.1-178.8-63.8-80.2000111.5Y20 C39 K41 E46 I79 V101 M102 M104Y20-F48 HydrophobicContact CD1-CD2 4.45Å; Y20-F48 AromaticContact CE1-CD2 3.73Å; Y20-F48 HydrophobicContact CE1-CD2 3.73Å; Y20-F48 HydrophobicContact CE1-CE2 4.16Å; Y20-F48 HydrophobicContact CE1-CG 4.36Å; C39-F48 PolarHBondContact N-O 3.32Å; C39-F48 PolarHBondContact O-N 2.92Å; K41-F48 HydrophobicContact CB-CD2 4.13Å; K41-F48 HydrophobicContact CB-CE2 3.66Å; K41-F48 HydrophobicContact CD-CE2 4.38Å; E46-F48 HydrophobicContact CB-CE2 3.68Å; E46-F48 HydrophobicContact CB-CZ 3.96Å; E46-F48 HydrophobicContact CG-CE1 4.35Å; E46-F48 HydrophobicContact CG-CE2 3.76Å; E46-F48 HydrophobicContact CG-CZ 3.63Å; E46-F48 VanDerWaalsContact O-CD2 3.27Å; E46-F48 WeakPolarHBondContact O-CD2 3.42Å; E46-F48 WeakPolarHBondContact O-CE2 3.42Å; E46-F48 WeakPolarHBondContact OE2-CZ 3.39Å; F48-I79 HydrophobicContact CD1-CG1 3.86Å; F48-I79 HydrophobicContact CE1-CD1 4.35Å; F48-I79 HydrophobicContact CE1-CG1 3.88Å; F48-I79 HydrophobicContact CE1-CG2 4.33Å; F48-V101 HydrophobicContact CB-CG1 3.64Å; F48-V101 HydrophobicContact CD1-CG1 4.2Å; F48-V101 HydrophobicContact CG-CG1 3.88Å; F48-M102 WeakPolarHBondContact CB-O 3.23Å; F48-M104 VanDerWaalsContact CA-CG 3.48Å
49A95.1Very high93.9Very high9 Ų959.2 Ų59.27%0.07430%0.296CS..EExtended strand (participates in β ladder)trans-95.5128.5172.200000109.3L28 V36 M102 M104L28-A49 HydrophobicContact CD1-CB 4.08Å; V36-A49 HydrophobicContact CG1-CB 4.21Å; A49-M102 HydrophobicContact CB-CB 4.41Å; A49-M102 HydrophobicContact CB-CE 4.37Å; A49-M102 PolarHBondContact N-O 3.44Å; A49-M102 PolarHBondContact O-N 3.05Å; A49-M104 HydrophobicContact CB-SD 3.8Å; A49-M104 PolarHBondContact N-SD 2.96Å
50L94.9Very high93.7Very high0 Ų063.4 Ų63.40%031%0.311CS..EExtended strand (participates in β ladder)trans-110.5108.7179.7-179.963.6000110.3I16 I22 V36 R37 C39 I52 L99 I100 V101I16-L50 HydrophobicContact CD1-CD1 3.71Å; I16-L50 HydrophobicContact CD1-CD2 4.26Å; I22-L50 HydrophobicContact CB-CD2 4.49Å; I22-L50 HydrophobicContact CD1-CD2 3.57Å; I22-L50 HydrophobicContact CG1-CD2 3.82Å; I22-L50 HydrophobicContact CG2-CD2 3.86Å; V36-L50 CarbonylContact C-O 3.51Å; V36-L50 VanDerWaalsContact CA-O 3.3Å; V36-L50 WeakPolarHBondContact CA-O 3.38Å; R37-L50 HydrophobicContact CB-CB 4.47Å; R37-L50 PolarHBondContact N-O 2.71Å; R37-L50 PolarHBondContact O-N 2.97Å; C39-L50 HydrophobicContact CB-CB 4.23Å; L50-I52 HydrophobicContact CD2-CD1 4.07Å; L50-I52 HydrophobicContact CD2-CG1 4.19Å; L50-I52 HydrophobicContact CG-CD1 4.26Å; L50-I52 HydrophobicContact CG-CG1 3.91Å; L50-L99 HydrophobicContact CD1-CB 4.05Å; L50-I100 WeakPolarHBondContact CA-O 3.27Å; L50-V101 HydrophobicContact CD1-CG2 4.09Å
51K92.9Very high93.3Very high10 Ų1064.5 Ų64.54%0.04332%0.316CS..EExtended strand (participates in β ladder)trans-91134.7170.9-175.4178.7-163.4179.20110.1S33 V36 L53 E62 I100 M102 D169S33-K51 VanDerWaalsContact CB-CE 3.45Å; V36-K51 HydrophobicContact CG2-CB 4.26Å; V36-K51 HydrophobicContact CG2-CG 4.24Å; K51-L53 HydrophobicContact CD-CD2 4.45Å; K51-L53 HydrophobicContact CG-CD2 4.22Å; K51-L53 HydrophobicContact CG-CG 4.45Å; K51-E62 WeakPolarHBondContact CE-OE1 3.3Å; K51-E62 IonicContact NZ-OE1 3.63Å; K51-E62 PolarHBondContact NZ-OE1 2.8Å; K51-I100 HydrophobicContact CB-CB 4.3Å; K51-I100 HydrophobicContact CB-CD1 4.39Å; K51-I100 HydrophobicContact CD-CD1 4.21Å; K51-I100 HydrophobicContact CG-CD1 4.36Å; K51-I100 PolarHBondContact N-O 2.84Å; K51-I100 PolarHBondContact O-N 3.43Å; K51-M102 HydrophobicContact CB-CE 3.66Å; K51-M102 HydrophobicContact CD-CE 4.44Å; K51-D169 IonicContact NZ-OD1 2.71Å; K51-D169 PolarHBondContact NZ-OD1 3.06Å
52I91.7Very high92.9Very high2 Ų262.9 Ų62.91%0.0131%0.309CS..EExtended strand (participates in β ladder)trans-123115-172.5-53.3169.7000110W24 P35 R37 L50 F88 R97 L99W24-I52 HydrophobicContact CH2-CD1 4.19Å; W24-I52 HydrophobicContact CZ3-CD1 3.72Å; P35-I52 WeakPolarHBondContact CD-O 3.48Å; P35-I52 HydrophobicContact CG-CB 4.39Å; P35-I52 PolarHBondContact O-N 2.9Å; P35-I52 VanDerWaalsContact O-N 3.13Å; R37-I52 HydrophobicContact CG-CD1 4.17Å; L50-I52 HydrophobicContact CD2-CD1 4.07Å; L50-I52 HydrophobicContact CD2-CG1 4.19Å; L50-I52 HydrophobicContact CG-CD1 4.26Å; L50-I52 HydrophobicContact CG-CG1 3.91Å; I52-F88 HydrophobicContact CB-CZ 4Å; I52-F88 HydrophobicContact CD1-CE1 4.35Å; I52-F88 HydrophobicContact CD1-CE2 4.41Å; I52-F88 HydrophobicContact CD1-CZ 3.59Å; I52-F88 HydrophobicContact CG1-CZ 4.37Å; I52-F88 HydrophobicContact CG2-CE2 3.57Å; I52-F88 HydrophobicContact CG2-CZ 3.55Å; I52-R97 HydrophobicContact CG2-CB 4.43Å; I52-R97 HydrophobicContact CG2-CG 4.45Å; I52-L99 HydrophobicContact CB-CD2 4.19Å; I52-L99 HydrophobicContact CG1-CD2 3.87Å; I52-L99 HydrophobicContact CG2-CD2 3.63Å
53L91Very high92.7Very high7 Ų758.7 Ų58.74%0.03729%0.291CS..EExtended strand (participates in β ladder)trans-116.4150.5-178.4-54.5-176.5000110.5S33 K51 D55 A59 R97 L98 I100S33-L53 WeakPolarHBondContact O-CD2 3.05Å; K51-L53 HydrophobicContact CD-CD2 4.45Å; K51-L53 HydrophobicContact CG-CD2 4.22Å; K51-L53 HydrophobicContact CG-CG 4.45Å; L53-D55 PolarHBondContact O-N 2.81Å; L53-A59 HydrophobicContact CB-CB 3.93Å; L53-A59 HydrophobicContact CD1-CB 3.8Å; L53-R97 CarbonylContact O-C 3.51Å; L53-R97 WeakPolarHBondContact O-CA 3.2Å; L53-R97 VanDerWaalsContact O-CB 3.23Å; L53-R97 WeakPolarHBondContact O-CB 3.42Å; L53-R97 WeakPolarHBondContact O-CG 3.5Å; L53-L98 HydrophobicContact CB-CB 4.4Å; L53-L98 PolarHBondContact N-O 3.28Å; L53-L98 PolarHBondContact O-N 3.28Å; L53-I100 HydrophobicContact CD1-CD1 3.63Å; L53-I100 HydrophobicContact CG-CD1 4.02Å
54L91.6Very high92.4Very high58 Ų5856.7 Ų56.730%0.30427%0.269SS..EExtended strand (participates in β ladder)trans-67.3133.2164-71.2173.6000108.9R56 A59 R95 R97L54-R56 HydrophobicContact CB-CG 4.2Å; L54-R56 PolarHBondContact O-N 2.84Å; L54-A59 WeakPolarHBondContact O-CB 3.36Å; L54-R95 HydrophobicContact CD2-CB 4.18Å; L54-R97 HydrophobicContact CD2-CG 4.4Å
55D93.1Very high92.1Very high36 Ų3652.9 Ų52.919%0.19325%0.245CC..  trans-70.1102179.4-170.32.9000110L53 R60 A96 L98L53-D55 PolarHBondContact O-N 2.81Å; D55-R60 WeakPolarHBondContact OD1-CG 3.43Å; D55-R60 IonicContact OD1-CZ 3.06Å; D55-R60 IonicContact OD1-NE 3.58Å; D55-R60 PolarHBondContact OD1-NE 2.72Å; D55-R60 IonicContact OD1-NH2 3.61Å; D55-R60 IonicContact OD2-CZ 2.77Å; D55-R60 IonicContact OD2-NE 2.73Å; D55-R60 PolarHBondContact OD2-NE 2.78Å; D55-R60 IonicContact OD2-NH2 3.54Å; D55-R60 PolarHBondContact OD2-NH2 2.83Å; D55-A96 HydrophobicContact CB-CB 4.08Å; D55-A96 PolarHBondContact N-O 2.93Å; D55-L98 HydrophobicContact CB-CD2 4.47Å; D55-L98 HydrophobicContact CB-CG 4.09Å
56R91Very high92Very high151 Ų15146.7 Ų46.757%0.5722%0.216SC*.  trans-142.8155.3-176.3-64.3-63.7-169.7-174.13.8108.2L54 K58 A59 R60L54-R56 HydrophobicContact CB-CG 4.2Å; L54-R56 PolarHBondContact O-N 2.84Å; R56-K58 PolarHBondContact O-N 2.85Å; R56-K58 VanDerWaalsContact O-N 3.09Å; R56-A59 WeakPolarHBondContact O-CB 3.42Å; R56-A59 PolarHBondContact O-N 3.29Å; R56-R60 PolarHBondContact O-N 3.03Å
57P88.5Confident91.8Very high110 Ų11043.4 Ų43.471%0.71420%0.201SC*.Hα-helixtrans-53-37.4179.3-2935.5000114.2R60 N61P57-R60 PolarHBondContact O-N 3.2Å; P57-N61 WeakPolarHBondContact O-CB 3.47Å; P57-N61 PolarHBondContact O-N 3.42Å
58K85.3Confident91.6Very high138 Ų13841.1 Ų41.160%0.620%0.196SC*.Hα-helixtrans-63.1-44176.1-171.2-176.1176.2-168.60112.2R56 N61 E62 G171R56-K58 PolarHBondContact O-N 2.85Å; R56-K58 VanDerWaalsContact O-N 3.09Å; K58-N61 PolarHBondContact O-N 3.33Å; K58-E62 PolarHBondContact O-N 3.15Å; K58-G171 WeakPolarHBondContact CE-O 3.04Å
59A89.8Confident91.4Very high9 Ų940.6 Ų40.67%0.07419%0.194CC..Hα-helixtrans-68.7-41.7178.800000111.3L53 L54 R56 N61 E62 V63 L98L53-A59 HydrophobicContact CB-CB 3.93Å; L53-A59 HydrophobicContact CD1-CB 3.8Å; L54-A59 WeakPolarHBondContact O-CB 3.36Å; R56-A59 WeakPolarHBondContact O-CB 3.42Å; R56-A59 PolarHBondContact O-N 3.29Å; A59-N61 VanDerWaalsContact C-N 3.3Å; A59-N61 PolarHBondContact O-N 2.87Å; A59-E62 WeakPolarHBondContact O-CB 3.23Å; A59-E62 PolarHBondContact O-N 3.45Å; A59-V63 WeakPolarHBondContact O-CG2 3.24Å; A59-V63 PolarHBondContact O-N 3.26Å; A59-L98 HydrophobicContact CB-CD1 3.9Å
60R91.4Very high91.2Very high88 Ų8840.8 Ų40.833%0.33220%0.195SC..Hα-helixtrans-59.3-41.8173.2-70.6-170.8173.4-123.5-4.7111.9D55 R56 P57 V63 R64 L98D55-R60 WeakPolarHBondContact OD1-CG 3.43Å; D55-R60 IonicContact OD1-CZ 3.06Å; D55-R60 IonicContact OD1-NE 3.58Å; D55-R60 PolarHBondContact OD1-NE 2.72Å; D55-R60 IonicContact OD1-NH2 3.61Å; D55-R60 IonicContact OD2-CZ 2.77Å; D55-R60 IonicContact OD2-NE 2.73Å; D55-R60 PolarHBondContact OD2-NE 2.78Å; D55-R60 IonicContact OD2-NH2 3.54Å; D55-R60 PolarHBondContact OD2-NH2 2.83Å; R56-R60 PolarHBondContact O-N 3.03Å; P57-R60 PolarHBondContact O-N 3.2Å; R60-V63 PolarHBondContact O-N 3.12Å; R60-R64 WeakPolarHBondContact O-CB 3.49Å; R60-R64 PolarHBondContact O-N 3.44Å; R60-L98 HydrophobicContact CB-CD1 4.38Å; R60-L98 HydrophobicContact CG-CD1 3.63Å
61N88.4Confident90.9Very high59 Ų5946.1 Ų46.132%0.31623%0.228SC..Hα-helixtrans-66-40.5175.4-176.573.6000112.4P57 K58 A59 R64 L65P57-N61 WeakPolarHBondContact O-CB 3.47Å; P57-N61 PolarHBondContact O-N 3.42Å; K58-N61 PolarHBondContact O-N 3.33Å; A59-N61 VanDerWaalsContact C-N 3.3Å; A59-N61 PolarHBondContact O-N 2.87Å; N61-R64 PolarHBondContact O-N 3.44Å; N61-R64 PolarHBondContact OD1-NH2 3.44Å; N61-L65 WeakPolarHBondContact ND2-CD1 3.46Å; N61-L65 VanDerWaalsContact O-CG 3.31Å; N61-L65 WeakPolarHBondContact O-CG 3.3Å; N61-L65 PolarHBondContact O-N 2.83Å
62E89.9Confident91.1Very high12 Ų1247 Ų476%0.05623%0.232CC..Hα-helixtrans-55.6-50.8173165.3-179.2171.300111.5K51 K58 A59 R64 L65 H66 F170 G171K51-E62 WeakPolarHBondContact CE-OE1 3.3Å; K51-E62 IonicContact NZ-OE1 3.63Å; K51-E62 PolarHBondContact NZ-OE1 2.8Å; K58-E62 PolarHBondContact O-N 3.15Å; A59-E62 WeakPolarHBondContact O-CB 3.23Å; A59-E62 PolarHBondContact O-N 3.45Å; E62-R64 VanDerWaalsContact C-N 3.32Å; E62-R64 PolarHBondContact O-N 3.28Å; E62-L65 PolarHBondContact O-N 3.34Å; E62-H66 WeakPolarHBondContact O-CB 3.33Å; E62-H66 PolarHBondContact O-N 2.9Å; E62-F170 HydrophobicContact CG-CB 4.34Å; E62-G171 VanDerWaalsContact OE2-CA 3.29Å; E62-G171 WeakPolarHBondContact OE2-CA 3.47Å
63V92.1Very high91.3Very high3 Ų350.7 Ų50.72%0.01826%0.256CS..Hα-helixtrans-59.8-45177.8-179.40000110.6A59 R60 L65 H66 M67 I78 V81 L98 I100A59-V63 WeakPolarHBondContact O-CG2 3.24Å; A59-V63 PolarHBondContact O-N 3.26Å; R60-V63 PolarHBondContact O-N 3.12Å; V63-L65 PolarHBondContact O-N 3Å; V63-H66 PolarHBondContact O-N 3.46Å; V63-M67 HydrophobicContact CG1-CE 3.55Å; V63-M67 HydrophobicContact CG1-CG 4.29Å; V63-M67 HydrophobicContact CG1-SD 4.31Å; V63-M67 WeakPolarHBondContact O-CB 3.44Å; V63-M67 WeakPolarHBondContact O-CG 3.45Å; V63-M67 PolarHBondContact O-N 2.93Å; V63-I78 HydrophobicContact CG1-CD1 4.49Å; V63-V81 HydrophobicContact CG1-CG1 4.06Å; V63-V81 HydrophobicContact CG1-CG2 3.73Å; V63-L98 HydrophobicContact CG2-CD1 4.25Å; V63-I100 HydrophobicContact CG2-CD1 3.5Å; V63-I100 VanDerWaalsContact CG2-CD1 3.5Å; V63-I100 HydrophobicContact CG2-CG1 3.76Å
64R91.5Very high91.6Very high57 Ų5751 Ų5122%0.21526%0.258CS..Hα-helixtrans-57.7-49.3179.8-171.2-174.966.179.90.7111.9M7 R60 N61 E62 M67 M68 I175M7-R64 HydrophobicContact CE-CB 3.99Å; M7-R64 HydrophobicContact CE-CG 3.55Å; R60-R64 WeakPolarHBondContact O-CB 3.49Å; R60-R64 PolarHBondContact O-N 3.44Å; N61-R64 PolarHBondContact O-N 3.44Å; N61-R64 PolarHBondContact OD1-NH2 3.44Å; E62-R64 VanDerWaalsContact C-N 3.32Å; E62-R64 PolarHBondContact O-N 3.28Å; R64-M67 PolarHBondContact O-N 2.88Å; R64-M68 PolarHBondContact NH1-SD 3.32Å; R64-M68 VanDerWaalsContact NH1-SD 3.38Å; R64-M68 VanDerWaalsContact O-CG 3.32Å; R64-M68 WeakPolarHBondContact O-CG 3.46Å; R64-M68 PolarHBondContact O-N 2.92Å; R64-M68 VanDerWaalsContact O-N 3.11Å; R64-I175 VanDerWaalsContact NH2-CD1 3.32Å
65L91.1Very high91.9Very high0 Ų048.3 Ų48.30%024%0.244CC..Hα-helixtrans-67.2-38.3-179.7-64.3-177.6000112.4N61 E62 V63 M68 C69 I144 F170 A173 I175N61-L65 WeakPolarHBondContact ND2-CD1 3.46Å; N61-L65 VanDerWaalsContact O-CG 3.31Å; N61-L65 WeakPolarHBondContact O-CG 3.3Å; N61-L65 PolarHBondContact O-N 2.83Å; E62-L65 PolarHBondContact O-N 3.34Å; V63-L65 PolarHBondContact O-N 3Å; L65-M68 HydrophobicContact CD2-SD 4.25Å; L65-M68 PolarHBondContact O-N 3.08Å; L65-C69 PolarHBondContact O-N 2.81Å; L65-I144 HydrophobicContact CB-CD1 4.49Å; L65-I144 HydrophobicContact CD2-CD1 3.89Å; L65-I144 HydrophobicContact CD2-CG1 4.1Å; L65-F170 HydrophobicContact CB-CD1 4.35Å; L65-A173 HydrophobicContact CB-CB 4.44Å; L65-A173 VanDerWaalsContact CD1-C 3.46Å; L65-A173 HydrophobicContact CD1-CB 3.91Å; L65-A173 VanDerWaalsContact CD1-O 3.26Å; L65-A173 WeakPolarHBondContact CD1-O 3.46Å; L65-I175 HydrophobicContact CD2-CD1 3.92Å; L65-I175 HydrophobicContact CD2-CG1 3.47Å; L65-I175 VanDerWaalsContact CD2-CG1 3.47Å
66H93.6Very high92.1Very high6 Ų646.7 Ų46.73%0.02824%0.235CC..Hα-helixtrans-64.2-48.1176.3-165.3168.9000110.6E62 V63 M68 C69 A70 V76 I78 F170E62-H66 WeakPolarHBondContact O-CB 3.33Å; E62-H66 PolarHBondContact O-N 2.9Å; V63-H66 PolarHBondContact O-N 3.46Å; H66-M68 VanDerWaalsContact C-N 3.31Å; H66-M68 PolarHBondContact O-N 3.33Å; H66-C69 CarbonylContact O-C 3.58Å; H66-C69 PolarHBondContact O-N 3.33Å; H66-A70 WeakPolarHBondContact O-CB 3.23Å; H66-A70 PolarHBondContact O-N 3.12Å; H66-V76 PolarHBondContact NE2-O 3Å; H66-I78 HydrophobicContact CB-CD1 3.66Å; H66-F170 HydrophobicContact CB-CB 3.92Å; H66-F170 HydrophobicContact CB-CD1 4.35Å; H66-F170 HydrophobicContact CB-CD2 3.82Å; H66-F170 HydrophobicContact CB-CE2 4.48Å; H66-F170 HydrophobicContact CB-CG 3.77Å; H66-F170 AromaticContact CD2-CD2 3.67Å; H66-F170 AromaticContact CD2-CE2 3.63Å; H66-F170 AromaticContact CG-CD2 3.46Å; H66-F170 VanDerWaalsContact CG-CD2 3.46Å; H66-F170 AromaticContact CG-CE2 3.93Å; H66-F170 AromaticContact CG-CG 3.96Å; H66-F170 AromaticContact ND1-CD2 3.79Å
67M92.2Very high92.3Very high41 Ų4143.5 Ų43.520%0.20223%0.227CC..Hα-helixtrans-58.4-39.7177.8-77.4-163.6-75.800112.8M7 V63 R64 C69 A70 I78 V81M7-M67 HydrophobicContact CE-CB 3.76Å; M7-M67 HydrophobicContact CE-CE 3.16Å; M7-M67 HydrophobicContact CE-CG 4.4Å; M7-M67 HydrophobicContact CE-SD 4.07Å; M7-M67 HydrophobicContact SD-CE 3.82Å; M7-M67 HydrophobicContact SD-SD 4.34Å; V63-M67 HydrophobicContact CG1-CE 3.55Å; V63-M67 HydrophobicContact CG1-CG 4.29Å; V63-M67 HydrophobicContact CG1-SD 4.31Å; V63-M67 WeakPolarHBondContact O-CB 3.44Å; V63-M67 WeakPolarHBondContact O-CG 3.45Å; V63-M67 PolarHBondContact O-N 2.93Å; R64-M67 PolarHBondContact O-N 2.88Å; M67-C69 PolarHBondContact O-N 3.3Å; M67-A70 PolarHBondContact O-N 3.4Å; M67-I78 HydrophobicContact CG-CB 4.33Å; M67-I78 HydrophobicContact CG-CD1 3.68Å; M67-I78 HydrophobicContact CG-CG2 4.22Å; M67-V81 HydrophobicContact SD-CG2 4.2Å
68M91.6Very high92.6Very high57 Ų5739.5 Ų39.528%0.28120%0.199SC..Hα-helixtrans-59-34.7174.8-71174.372.500112.5R64 L65 H66 L142 I144R64-M68 PolarHBondContact NH1-SD 3.32Å; R64-M68 VanDerWaalsContact NH1-SD 3.38Å; R64-M68 VanDerWaalsContact O-CG 3.32Å; R64-M68 WeakPolarHBondContact O-CG 3.46Å; R64-M68 PolarHBondContact O-N 2.92Å; R64-M68 VanDerWaalsContact O-N 3.11Å; L65-M68 HydrophobicContact CD2-SD 4.25Å; L65-M68 PolarHBondContact O-N 3.08Å; H66-M68 VanDerWaalsContact C-N 3.31Å; H66-M68 PolarHBondContact O-N 3.33Å; M68-L142 WeakPolarHBondContact O-CD1 3.5Å; M68-I144 HydrophobicContact CB-CD1 4.14Å; M68-I144 HydrophobicContact CE-CD1 4.25Å; M68-I144 HydrophobicContact SD-CD1 4.25Å
69C93.1Very high93.1Very high0 Ų036 Ų360%019%0.187CC..Hα-helixtrans-94.7-15-178.4-630000114.2L65 H66 M67 T71 H72 I75 H138 C139 I144 F170L65-C69 PolarHBondContact O-N 2.81Å; H66-C69 CarbonylContact O-C 3.58Å; H66-C69 PolarHBondContact O-N 3.33Å; M67-C69 PolarHBondContact O-N 3.3Å; C69-T71 PolarHBondContact O-N 3.32Å; C69-H72 PolarHBondContact O-N 2.99Å; C69-I75 HydrophobicContact CB-CD1 3.72Å; C69-I75 HydrophobicContact CB-CG2 4.45Å; C69-I75 WeakPolarHBondContact O-CD1 3.38Å; C69-H138 PolarHBondContact O-NE2 3.42Å; C69-C139 VanDerWaalsContact SG-SG 3.65Å; C69-I144 VanDerWaalsContact SG-CD1 3.58Å; C69-F170 HydrophobicContact CB-CE1 3.86Å; C69-F170 HydrophobicContact CB-CZ 3.85Å
70A90.9Very high93.4Very high13 Ų1337 Ų3711%0.10719%0.19CC..THydrogen-bonded Turntrans-67.9-4.9-169.700000114.4H66 M67 H72H66-A70 WeakPolarHBondContact O-CB 3.23Å; H66-A70 PolarHBondContact O-N 3.12Å; M67-A70 PolarHBondContact O-N 3.4Å; A70-H72 VanDerWaalsContact C-N 3.28Å
71T88.3Confident93.6Very high111 Ų11133 Ų3368%0.68118%0.175SC*.THydrogen-bonded Turntrans-73.9-18.7174.559.80000112.9C69C69-T71 PolarHBondContact O-N 3.32Å
72H96.4Very high94Very high28 Ų2830.2 Ų30.213%0.1316%0.16CC..SBendtrans-81.8136.4-177.5-168.2-86.2000112.3C69 A70 N74 I75 H138C69-H72 PolarHBondContact O-N 2.99Å; A70-H72 VanDerWaalsContact C-N 3.28Å; H72-N74 VanDerWaalsContact C-N 3.26Å; H72-N74 PolarHBondContact CE1-OD1 2.95Å; H72-N74 PolarHBondContact ND1-N 3.42Å; H72-N74 VanDerWaalsContact ND1-N 3.16Å; H72-N74 PolarHBondContact O-N 2.97Å; H72-I75 HydrophobicContact CB-CB 4.39Å; H72-I75 HydrophobicContact CB-CD1 3.99Å; H72-I75 HydrophobicContact CB-CG1 4.13Å; H72-I75 PolarHBondContact O-N 3.45Å; H72-H138 HydrophobicContact CB-CB 4.22Å; H72-H138 AromaticContact CD2-CG 3.76Å; H72-H138 AromaticContact CG-CG 3.95Å
73P96.8Very high94.3Very high81 Ų8130.7 Ų30.753%0.52617%0.166SC..THydrogen-bonded Turntrans-61.8-29.3-175.423.3-35.2000114.3I75 K166P73-I75 VanDerWaalsContact C-N 3.32Å; P73-K166 WeakPolarHBondContact O-CD 3.11Å; P73-K166 WeakPolarHBondContact O-CE 3.36Å; P73-K166 PolarHBondContact O-NZ 3.37Å
74N97.9Very high94.4Very high14 Ų1431.4 Ų31.48%0.07517%0.17CC..THydrogen-bonded Turntrans-91.619.2177.2-58.1109.2000114H72 Q131 A135 V165 K166 L167H72-N74 VanDerWaalsContact C-N 3.26Å; H72-N74 PolarHBondContact CE1-OD1 2.95Å; H72-N74 PolarHBondContact ND1-N 3.42Å; H72-N74 VanDerWaalsContact ND1-N 3.16Å; H72-N74 PolarHBondContact O-N 2.97Å; N74-Q131 WeakPolarHBondContact CB-O 3.29Å; N74-Q131 WeakPolarHBondContact ND2-CB 3.26Å; N74-Q131 PolarHBondContact ND2-OE1 3.33Å; N74-A135 HydrophobicContact CB-CB 3.86Å; N74-A135 WeakPolarHBondContact O-CB 3.36Å; N74-V165 PolarHBondContact ND2-O 3.29Å; N74-K166 CarbonylContact O-C 3.5Å; N74-K166 VanDerWaalsContact O-CA 3.27Å; N74-K166 WeakPolarHBondContact O-CA 3.46Å; N74-L167 PolarHBondContact O-N 2.73Å
75I97.6Very high94.4Very high0 Ų032.9 Ų32.90%019%0.189CC..BIsolated β-bridgetrans-124.4136.7172.8-62.6-179.9000107.4C69 H72 P73 Q77 A135 L167 F170C69-I75 HydrophobicContact CB-CD1 3.72Å; C69-I75 HydrophobicContact CB-CG2 4.45Å; C69-I75 WeakPolarHBondContact O-CD1 3.38Å; H72-I75 HydrophobicContact CB-CB 4.39Å; H72-I75 HydrophobicContact CB-CD1 3.99Å; H72-I75 HydrophobicContact CB-CG1 4.13Å; H72-I75 PolarHBondContact O-N 3.45Å; P73-I75 VanDerWaalsContact C-N 3.32Å; I75-Q77 PolarHBondContact O-N 3.43Å; I75-A135 HydrophobicContact CD1-CB 4.35Å; I75-A135 HydrophobicContact CG1-CB 3.86Å; I75-L167 HydrophobicContact CG1-CB 4.49Å; I75-F170 HydrophobicContact CD1-CZ 4.35Å; I75-F170 HydrophobicContact CG2-CE2 3.86Å; I75-F170 HydrophobicContact CG2-CZ 3.9Å
76V96.2Very high94.1Very high3 Ų334.1 Ų34.12%0.01820%0.196CC..PPolyproline II helixtrans-60.1127.2179.8170.10000109.5H66 M102 E103 M105 K166 L167 C168H66-V76 PolarHBondContact NE2-O 3Å; V76-M102 HydrophobicContact CG1-CB 3.98Å; V76-M102 HydrophobicContact CG1-CG 4.47Å; V76-M102 HydrophobicContact CG1-SD 4.28Å; V76-E103 WeakPolarHBondContact CA-OE1 3.5Å; V76-E103 HydrophobicContact CG1-CG 3.91Å; V76-M105 HydrophobicContact CG2-CE 4.34Å; V76-M105 HydrophobicContact CG2-CG 3.99Å; V76-M105 HydrophobicContact CG2-SD 4.03Å; V76-K166 HydrophobicContact CG2-CB 3.9Å; V76-L167 PolarHBondContact N-O 3.3Å; V76-C168 HydrophobicContact CB-CB 4.1Å; V76-C168 HydrophobicContact CG2-CB 3.61Å
77Q95.7Very high93.7Very high83 Ų8338.9 Ų38.939%0.38822%0.218SC..PPolyproline II helixtrans-74134.1-179.9-68-176.3-10.500111.6I75 I79 M102 E103I75-Q77 PolarHBondContact O-N 3.43Å; Q77-I79 HydrophobicContact CB-CD1 4.27Å; Q77-M102 VanDerWaalsContact O-CA 3.24Å; Q77-M102 WeakPolarHBondContact O-CA 3.44Å; Q77-M102 WeakPolarHBondContact O-CB 3.27Å; Q77-E103 HydrophobicContact CB-CB 4.44Å; Q77-E103 HydrophobicContact CB-CG 4.18Å; Q77-E103 PolarHBondContact N-OE1 3.41Å; Q77-E103 PolarHBondContact O-N 2.99Å
78I94.9Very high92.9Very high27 Ų2738.3 Ų38.314%0.13822%0.215CC..EExtended strand (participates in β ladder)trans-86.5124.1162.3-67.9177000107.1V63 H66 M67 V81 I100 M102V63-I78 HydrophobicContact CG1-CD1 4.49Å; H66-I78 HydrophobicContact CB-CD1 3.66Å; M67-I78 HydrophobicContact CG-CB 4.33Å; M67-I78 HydrophobicContact CG-CD1 3.68Å; M67-I78 HydrophobicContact CG-CG2 4.22Å; I78-V81 HydrophobicContact CG2-CG2 3.65Å; I78-I100 HydrophobicContact CD1-CG2 3.94Å; I78-I100 HydrophobicContact CG1-CG2 3.92Å; I78-I100 HydrophobicContact CG2-CG2 4.12Å; I78-M102 HydrophobicContact CG1-CG 4.29Å
79I95.7Very high92Very high65 Ų6539.7 Ų39.733%0.33323%0.228SC..EExtended strand (participates in β ladder)trans-86.7-55.3178.6-47.9-57.8000108.5F48 Q77 V101 E103F48-I79 HydrophobicContact CD1-CG1 3.86Å; F48-I79 HydrophobicContact CE1-CD1 4.35Å; F48-I79 HydrophobicContact CE1-CG1 3.88Å; F48-I79 HydrophobicContact CE1-CG2 4.33Å; Q77-I79 HydrophobicContact CB-CD1 4.27Å; I79-V101 HydrophobicContact CB-CB 4.46Å; I79-V101 HydrophobicContact CB-CG1 4.13Å; I79-V101 HydrophobicContact CG1-CG1 4.47Å; I79-V101 PolarHBondContact N-O 2.91Å; I79-E103 HydrophobicContact CD1-CB 4.44Å
80E95.6Very high91.1Very high30 Ų3049 Ų4914%0.1427%0.271CS..EExtended strand (participates in β ladder)trans-150.8152.9-175.4-65.3179.286.300110.6K12 Y20 K41 F82 V101K12-E80 VanDerWaalsContact CE-OE1 3.23Å; K12-E80 WeakPolarHBondContact CE-OE1 3.49Å; K12-E80 IonicContact NZ-OE1 3.43Å; K12-E80 PolarHBondContact NZ-OE1 3Å; Y20-E80 PolarHBondContact OH-OE2 3.45Å; K41-E80 IonicContact NZ-OE2 2.95Å; K41-E80 PolarHBondContact NZ-OE2 2.85Å; E80-F82 HydrophobicContact CB-CE2 3.73Å; E80-F82 HydrophobicContact CB-CZ 4.32Å; E80-V101 HydrophobicContact CB-CB 4.35Å; E80-V101 PolarHBondContact N-O 2.9Å; E80-V101 WeakPolarHBondContact O-CB 3.47Å; E80-V101 PolarHBondContact O-N 2.73Å
81V96.1Very high90.7Very high4 Ų450.7 Ų50.72%0.02428%0.277CS..EExtended strand (participates in β ladder)trans-128.3131176.7-172.90000109.3I11 K12 V63 M67 I78 L99 I100I11-V81 HydrophobicContact CG1-CB 4.42Å; I11-V81 HydrophobicContact CG1-CG1 4.16Å; I11-V81 HydrophobicContact CG2-CG1 4.32Å; K12-V81 PolarHBondContact N-O 2.85Å; V63-V81 HydrophobicContact CG1-CG1 4.06Å; V63-V81 HydrophobicContact CG1-CG2 3.73Å; M67-V81 HydrophobicContact SD-CG2 4.2Å; I78-V81 HydrophobicContact CG2-CG2 3.65Å; V81-L99 WeakPolarHBondContact CA-O 3.31Å; V81-I100 HydrophobicContact CG1-CG1 4.45Å; V81-I100 HydrophobicContact CG2-CG2 4.43Å
82F96.5Very high90.6Very high0 Ų051.3 Ų51.30%029%0.285CS..EExtended strand (participates in β ladder)trans-119.2141.6176.2-55.4-106.8000110.8K12 I16 Y20 E80 L98 L99 V101K12-F82 HydrophobicContact CB-CD1 3.54Å; K12-F82 HydrophobicContact CB-CE1 3.87Å; K12-F82 HydrophobicContact CB-CG 4.14Å; K12-F82 HydrophobicContact CD-CD1 3.95Å; K12-F82 HydrophobicContact CD-CE1 3.37Å; K12-F82 HydrophobicContact CD-CE2 4.45Å; K12-F82 HydrophobicContact CD-CZ 3.65Å; K12-F82 HydrophobicContact CG-CD1 4.39Å; K12-F82 HydrophobicContact CG-CE1 4.27Å; K12-F82 CarbonylContact O-C 3.49Å; K12-F82 VanDerWaalsContact O-CA 3.23Å; K12-F82 WeakPolarHBondContact O-CA 3.44Å; I16-F82 HydrophobicContact CB-CB 4.31Å; I16-F82 HydrophobicContact CB-CD1 4.06Å; I16-F82 HydrophobicContact CB-CD2 4.17Å; I16-F82 HydrophobicContact CB-CE1 4.43Å; I16-F82 HydrophobicContact CB-CG 3.93Å; I16-F82 HydrophobicContact CD1-CD2 3.76Å; I16-F82 HydrophobicContact CD1-CE2 4.11Å; I16-F82 HydrophobicContact CD1-CG 4.32Å; I16-F82 HydrophobicContact CG1-CD1 4.46Å; I16-F82 HydrophobicContact CG1-CD2 3.84Å; I16-F82 HydrophobicContact CG1-CE2 3.93Å; I16-F82 HydrophobicContact CG1-CG 4.14Å; I16-F82 HydrophobicContact CG1-CZ 4.28Å; Y20-F82 HydrophobicContact CD2-CE2 4.31Å; Y20-F82 HydrophobicContact CD2-CZ 4.21Å; Y20-F82 HydrophobicContact CE2-CE2 4.05Å; Y20-F82 AromaticContact CE2-CZ 3.98Å; Y20-F82 HydrophobicContact CE2-CZ 3.98Å; E80-F82 HydrophobicContact CB-CE2 3.73Å; E80-F82 HydrophobicContact CB-CZ 4.32Å; F82-L98 CarbonylContact O-C 3.57Å; F82-L98 WeakPolarHBondContact O-CA 3.47Å; F82-L99 HydrophobicContact CB-CB 4.12Å; F82-L99 HydrophobicContact CB-CD1 4.42Å; F82-L99 PolarHBondContact N-O 2.83Å; F82-L99 PolarHBondContact O-N 3.04Å; F82-V101 HydrophobicContact CD2-CG2 4.29Å; F82-V101 HydrophobicContact CE2-CG2 3.97Å
83A95.8Very high90.2Very high21 Ų2153 Ų5317%0.17430%0.301CS..EExtended strand (participates in β ladder)trans-107.8101.7168.100000108.7I11 K12 R97 L98I11-A83 HydrophobicContact CG2-CB 3.57Å; K12-A83 PolarHBondContact O-N 3.19Å; A83-R97 WeakPolarHBondContact CA-O 3.48Å; A83-L98 HydrophobicContact CB-CD2 4.14Å
84N94.3Very high89.8Confident19 Ų1952.7 Ų52.710%0.10230%0.298CS..EExtended strand (participates in β ladder)trans-130.6157.5-177.6-62.3161.2000111.3E13 T14 I16 V86 R97 L99E13-N84 PolarHBondContact O-ND2 3.39Å; T14-N84 PolarHBondContact O-ND2 3.49Å; T14-N84 PolarHBondContact O-OD1 3.35Å; I16-N84 PolarHBondContact N-OD1 2.96Å; N84-V86 HydrophobicContact CB-CG2 4.11Å; N84-R97 PolarHBondContact N-O 2.71Å; N84-R97 PolarHBondContact O-N 2.93Å; N84-L99 HydrophobicContact CB-CD1 3.95Å
85S93Very high89.5Confident88 Ų8856.8 Ų56.862%0.61531%0.313SS*.EExtended strand (participates in β ladder)trans-88.3108.7167.7-730000109.9R95S85-R95 WeakPolarHBondContact CA-O 3.33Å
86V84.9Confident89.4Confident25 Ų2559.3 Ų59.315%0.15233%0.334CS..EExtended strand (participates in β ladder)trans-122.8134.3-179.3-172.40000110.4W24 N84 R95 R97 L99W24-V86 HydrophobicContact CH2-CG1 3.78Å; W24-V86 HydrophobicContact CZ2-CG1 4.21Å; N84-V86 HydrophobicContact CB-CG2 4.11Å; V86-R95 PolarHBondContact N-O 3.2Å; V86-R95 PolarHBondContact O-N 3.4Å; V86-R97 PolarHBondContact O-NE 2.94Å; V86-L99 HydrophobicContact CG2-CD1 3.97Å
87Q83.6Confident89.2Confident107 Ų10759.8 Ų59.850%0.534%0.335SS..PPolyproline II helixtrans-93.8123.4174-173.81772.700109.8E91 P94Q87-E91 HydrophobicContact CG-CB 4.28Å; Q87-E91 PolarHBondContact NE2-O 3.4Å; Q87-P94 HydrophobicContact CB-CB 4.29Å; Q87-P94 HydrophobicContact CB-CG 4.16Å
88F76.8Confident89.2Confident28 Ų2855.9 Ų55.912%0.12332%0.317CS..PPolyproline II helixtrans-82.4157.6171-88.2-104.9000111.4W24 P35 I52 H90 E91 R97W24-F88 HydrophobicContact CZ3-CE1 4.12Å; W24-F88 HydrophobicContact CZ3-CE2 4.46Å; W24-F88 HydrophobicContact CZ3-CZ 4.03Å; P35-F88 HydrophobicContact CG-CE1 4.03Å; P35-F88 HydrophobicContact CG-CZ 4.04Å; I52-F88 HydrophobicContact CB-CZ 4Å; I52-F88 HydrophobicContact CD1-CE1 4.35Å; I52-F88 HydrophobicContact CD1-CE2 4.41Å; I52-F88 HydrophobicContact CD1-CZ 3.59Å; I52-F88 HydrophobicContact CG1-CZ 4.37Å; I52-F88 HydrophobicContact CG2-CE2 3.57Å; I52-F88 HydrophobicContact CG2-CZ 3.55Å; F88-H90 PolarHBondContact O-N 2.97Å; F88-E91 HydrophobicContact CB-CG 4.16Å; F88-E91 PolarHBondContact N-OE2 2.95Å; F88-E91 PolarHBondContact O-N 3.48Å; F88-R97 VanDerWaalsContact CD2-NH2 3.31Å
89P71.1Confident89.2Confident86 Ų8654.6 Ų54.656%0.55831%0.31SS*.THydrogen-bonded Turntrans-50131.6162.9-23.233.7000109.1
90H74.8Confident89.2Confident197 Ų19751.6 Ų51.691%0.91230%0.295SS*.THydrogen-bonded Turntrans79.33.5-177.2-38.8-68.7000117.3F88F88-H90 PolarHBondContact O-N 2.97Å
91E83.4Confident89.2Confident47 Ų4750.2 Ų50.222%0.2229%0.289CS..  trans-93.5140.1168.7-68.2-173.1148.700111.7Q87 F88 R95 R97Q87-E91 HydrophobicContact CG-CB 4.28Å; Q87-E91 PolarHBondContact NE2-O 3.4Å; F88-E91 HydrophobicContact CB-CG 4.16Å; F88-E91 PolarHBondContact N-OE2 2.95Å; F88-E91 PolarHBondContact O-N 3.48Å; E91-R95 WeakPolarHBondContact OE1-CD 3.09Å; E91-R95 IonicContact OE1-NH1 2.64Å; E91-R97 IonicContact OE1-CZ 2.73Å; E91-R97 IonicContact OE1-NH2 2.61Å; E91-R97 PolarHBondContact OE1-NH2 3.39Å; E91-R97 IonicContact OE2-CZ 3.74Å; E91-R97 IonicContact OE2-NH2 2.7Å; E91-R97 PolarHBondContact OE2-NH2 2.98Å
92S85.1Confident89.2Confident124 Ų12450.8 Ų50.887%0.86729%0.291SS*.SBendtrans-78.1-18.2-179.942.50000114.1
93S88.3Confident89.2Confident65 Ų6551.5 Ų51.546%0.45529%0.294SS..SBendtrans-151.6154.5177.352.50000111.3
94P89.1Confident89.1Confident73 Ų7351.3 Ų51.347%0.47429%0.29SS..  trans-58.2145.6170.9-20.731.2000111.7Q87Q87-P94 HydrophobicContact CB-CB 4.29Å; Q87-P94 HydrophobicContact CB-CG 4.16Å
95R91.9Very high89.1Confident100 Ų10051.9 Ų51.938%0.37729%0.293SS..EExtended strand (participates in β ladder)trans-125.9145.2177-59.4179.972.5-179.25.3110.2L54 S85 V86 E91 R97L54-R95 HydrophobicContact CD2-CB 4.18Å; S85-R95 WeakPolarHBondContact CA-O 3.33Å; V86-R95 PolarHBondContact N-O 3.2Å; V86-R95 PolarHBondContact O-N 3.4Å; E91-R95 WeakPolarHBondContact OE1-CD 3.09Å; E91-R95 IonicContact OE1-NH1 2.64Å; R95-R97 WeakPolarHBondContact O-CG 3.24Å; R95-R97 PolarHBondContact O-N 3.09Å
96A94Very high89.1Confident53 Ų5352.1 Ų52.144%0.43828%0.284SS..EExtended strand (participates in β ladder)trans-62.3126.6172.300000110.4D55D55-A96 HydrophobicContact CB-CB 4.08Å; D55-A96 PolarHBondContact N-O 2.93Å
97R93.6Very high89.3Confident14 Ų1451 Ų515%0.05328%0.278CS..EExtended strand (participates in β ladder)trans-139.2146.4-173.7-70.9172.4-170.1-75-3.2111.4I52 L53 L54 A83 N84 V86 F88 E91 R95 L99I52-R97 HydrophobicContact CG2-CB 4.43Å; I52-R97 HydrophobicContact CG2-CG 4.45Å; L53-R97 CarbonylContact O-C 3.51Å; L53-R97 WeakPolarHBondContact O-CA 3.2Å; L53-R97 VanDerWaalsContact O-CB 3.23Å; L53-R97 WeakPolarHBondContact O-CB 3.42Å; L53-R97 WeakPolarHBondContact O-CG 3.5Å; L54-R97 HydrophobicContact CD2-CG 4.4Å; A83-R97 WeakPolarHBondContact CA-O 3.48Å; N84-R97 PolarHBondContact N-O 2.71Å; N84-R97 PolarHBondContact O-N 2.93Å; V86-R97 PolarHBondContact O-NE 2.94Å; F88-R97 VanDerWaalsContact CD2-NH2 3.31Å; E91-R97 IonicContact OE1-CZ 2.73Å; E91-R97 IonicContact OE1-NH2 2.61Å; E91-R97 PolarHBondContact OE1-NH2 3.39Å; E91-R97 IonicContact OE2-CZ 3.74Å; E91-R97 IonicContact OE2-NH2 2.7Å; E91-R97 PolarHBondContact OE2-NH2 2.98Å; R95-R97 WeakPolarHBondContact O-CG 3.24Å; R95-R97 PolarHBondContact O-N 3.09Å; R97-L99 HydrophobicContact CB-CD2 4.27Å
98L94.8Very high89.7Confident0 Ų047.1 Ų47.10%027%0.266CS..EExtended strand (participates in β ladder)trans-92.9127.6165-60.9171.8000108.5L53 D55 A59 R60 V63 F82 A83L53-L98 HydrophobicContact CB-CB 4.4Å; L53-L98 PolarHBondContact N-O 3.28Å; L53-L98 PolarHBondContact O-N 3.28Å; D55-L98 HydrophobicContact CB-CD2 4.47Å; D55-L98 HydrophobicContact CB-CG 4.09Å; A59-L98 HydrophobicContact CB-CD1 3.9Å; R60-L98 HydrophobicContact CB-CD1 4.38Å; R60-L98 HydrophobicContact CG-CD1 3.63Å; V63-L98 HydrophobicContact CG2-CD1 4.25Å; F82-L98 CarbonylContact O-C 3.57Å; F82-L98 WeakPolarHBondContact O-CA 3.47Å; A83-L98 HydrophobicContact CB-CD2 4.14Å
99L95.1Very high90.3Very high0 Ų049 Ų490%028%0.276CS..EExtended strand (participates in β ladder)trans-116.5105.7-176.5-57.1178.7000107.4I16 L50 I52 V81 F82 N84 V86 R97I16-L99 HydrophobicContact CB-CD1 4Å; I16-L99 HydrophobicContact CD1-CB 3.95Å; I16-L99 HydrophobicContact CD1-CD1 4.12Å; I16-L99 HydrophobicContact CG2-CD1 3.52Å; L50-L99 HydrophobicContact CD1-CB 4.05Å; I52-L99 HydrophobicContact CB-CD2 4.19Å; I52-L99 HydrophobicContact CG1-CD2 3.87Å; I52-L99 HydrophobicContact CG2-CD2 3.63Å; V81-L99 WeakPolarHBondContact CA-O 3.31Å; F82-L99 HydrophobicContact CB-CB 4.12Å; F82-L99 HydrophobicContact CB-CD1 4.42Å; F82-L99 PolarHBondContact N-O 2.83Å; F82-L99 PolarHBondContact O-N 3.04Å; N84-L99 HydrophobicContact CB-CD1 3.95Å; V86-L99 HydrophobicContact CG2-CD1 3.97Å; R97-L99 HydrophobicContact CB-CD2 4.27Å
100I95.1Very high91.3Very high3 Ų344.9 Ų44.92%0.01525%0.249CC..EExtended strand (participates in β ladder)trans-106.1107.2-169.9-50.1153.7000107.2L50 K51 L53 V63 I78 V81 M102L50-I100 WeakPolarHBondContact CA-O 3.27Å; K51-I100 HydrophobicContact CB-CB 4.3Å; K51-I100 HydrophobicContact CB-CD1 4.39Å; K51-I100 HydrophobicContact CD-CD1 4.21Å; K51-I100 HydrophobicContact CG-CD1 4.36Å; K51-I100 PolarHBondContact N-O 2.84Å; K51-I100 PolarHBondContact O-N 3.43Å; L53-I100 HydrophobicContact CD1-CD1 3.63Å; L53-I100 HydrophobicContact CG-CD1 4.02Å; V63-I100 HydrophobicContact CG2-CD1 3.5Å; V63-I100 VanDerWaalsContact CG2-CD1 3.5Å; V63-I100 HydrophobicContact CG2-CG1 3.76Å; I78-I100 HydrophobicContact CD1-CG2 3.94Å; I78-I100 HydrophobicContact CG1-CG2 3.92Å; I78-I100 HydrophobicContact CG2-CG2 4.12Å; V81-I100 HydrophobicContact CG1-CG1 4.45Å; V81-I100 HydrophobicContact CG2-CG2 4.43Å; I100-M102 HydrophobicContact CG2-CG 3.87Å; I100-M102 HydrophobicContact CG2-SD 4.31Å
101V96.4Very high92Very high0 Ų035.6 Ų35.60%021%0.206CC..EExtended strand (participates in β ladder)trans-82.7121.9174.4-175.40000107.7I16 Y20 F48 L50 I79 E80 F82I16-V101 HydrophobicContact CD1-CG2 3.98Å; Y20-V101 HydrophobicContact CE1-CG1 3.83Å; Y20-V101 HydrophobicContact CE1-CG2 4.47Å; Y20-V101 HydrophobicContact CE2-CG2 4.31Å; F48-V101 HydrophobicContact CB-CG1 3.64Å; F48-V101 HydrophobicContact CD1-CG1 4.2Å; F48-V101 HydrophobicContact CG-CG1 3.88Å; L50-V101 HydrophobicContact CD1-CG2 4.09Å; I79-V101 HydrophobicContact CB-CB 4.46Å; I79-V101 HydrophobicContact CB-CG1 4.13Å; I79-V101 HydrophobicContact CG1-CG1 4.47Å; I79-V101 PolarHBondContact N-O 2.91Å; E80-V101 HydrophobicContact CB-CB 4.35Å; E80-V101 PolarHBondContact N-O 2.9Å; E80-V101 WeakPolarHBondContact O-CB 3.47Å; E80-V101 PolarHBondContact O-N 2.73Å; F82-V101 HydrophobicContact CD2-CG2 4.29Å; F82-V101 HydrophobicContact CE2-CG2 3.97Å
102M96Very high92.1Very high17 Ų1736.5 Ų36.58%0.08421%0.21CC..EExtended strand (participates in β ladder)trans-125158.4-177.6-59.5178-60.700110F48 A49 K51 V76 Q77 I78 I100F48-M102 WeakPolarHBondContact CB-O 3.23Å; A49-M102 HydrophobicContact CB-CB 4.41Å; A49-M102 HydrophobicContact CB-CE 4.37Å; A49-M102 PolarHBondContact N-O 3.44Å; A49-M102 PolarHBondContact O-N 3.05Å; K51-M102 HydrophobicContact CB-CE 3.66Å; K51-M102 HydrophobicContact CD-CE 4.44Å; V76-M102 HydrophobicContact CG1-CB 3.98Å; V76-M102 HydrophobicContact CG1-CG 4.47Å; V76-M102 HydrophobicContact CG1-SD 4.28Å; Q77-M102 VanDerWaalsContact O-CA 3.24Å; Q77-M102 WeakPolarHBondContact O-CA 3.44Å; Q77-M102 WeakPolarHBondContact O-CB 3.27Å; I78-M102 HydrophobicContact CG1-CG 4.29Å; I100-M102 HydrophobicContact CG2-CG 3.87Å; I100-M102 HydrophobicContact CG2-SD 4.31Å
103E95.4Very high92.3Very high14 Ų1431.6 Ų31.67%0.06517%0.172CC..EExtended strand (participates in β ladder)trans-56.8145.817167.5174.8135.500111.6V76 Q77 I79 M105 K157 K166V76-E103 WeakPolarHBondContact CA-OE1 3.5Å; V76-E103 HydrophobicContact CG1-CG 3.91Å; Q77-E103 HydrophobicContact CB-CB 4.44Å; Q77-E103 HydrophobicContact CB-CG 4.18Å; Q77-E103 PolarHBondContact N-OE1 3.41Å; Q77-E103 PolarHBondContact O-N 2.99Å; I79-E103 HydrophobicContact CD1-CB 4.44Å; E103-M105 HydrophobicContact CG-SD 4.08Å; E103-K157 WeakPolarHBondContact OE2-CE 3.47Å; E103-K157 IonicContact OE2-NZ 2.77Å; E103-K157 PolarHBondContact OE2-NZ 3.09Å; E103-K166 WeakPolarHBondContact OE1-CD 3.5Å; E103-K166 IonicContact OE1-NZ 2.74Å; E103-K166 PolarHBondContact OE1-NZ 2.88Å; E103-K166 IonicContact OE2-NZ 3.5Å; E103-K166 PolarHBondContact OE2-NZ 2.9Å
104M94.4Very high92.3Very high17 Ų1728.7 Ų28.78%0.08415%0.152CC..  trans-71.8140.5173.5-78.8-63.1-77.100111.6L28 V38 R47 F48 A49 E106 K157L28-M104 HydrophobicContact CD1-CE 3.9Å; L28-M104 HydrophobicContact CD1-SD 3.84Å; L28-M104 HydrophobicContact CD2-CE 4.31Å; V38-M104 HydrophobicContact CG2-CE 4.31Å; R47-M104 VanDerWaalsContact C-CG 3.43Å; R47-M104 HydrophobicContact CB-CG 4.14Å; R47-M104 WeakPolarHBondContact O-CG 3.49Å; F48-M104 VanDerWaalsContact CA-CG 3.48Å; A49-M104 HydrophobicContact CB-SD 3.8Å; A49-M104 PolarHBondContact N-SD 2.96Å; M104-E106 HydrophobicContact CB-CG 4.34Å; M104-E106 HydrophobicContact CE-CG 4.35Å; M104-K157 WeakPolarHBondContact O-CD 3.12Å; M104-K157 PolarHBondContact O-NZ 3.17Å
105M94.4Very high92.1Very high31 Ų3126.1 Ų26.115%0.15314%0.136CC..  trans-121.297.5175-57.2-57.8-67.600108.4V76 E103 L155 K157 K166V76-M105 HydrophobicContact CG2-CE 4.34Å; V76-M105 HydrophobicContact CG2-CG 3.99Å; V76-M105 HydrophobicContact CG2-SD 4.03Å; E103-M105 HydrophobicContact CG-SD 4.08Å; M105-L155 HydrophobicContact CB-CB 3.93Å; M105-L155 HydrophobicContact CB-CD1 3.91Å; M105-L155 HydrophobicContact CE-CB 3.9Å; M105-L155 VanDerWaalsContact CE-O 3.23Å; M105-L155 WeakPolarHBondContact CE-O 3.38Å; M105-L155 HydrophobicContact CG-CB 4.2Å; M105-L155 HydrophobicContact CG-CD1 4.08Å; M105-K157 VanDerWaalsContact CE-CA 3.49Å; M105-K157 HydrophobicContact CE-CB 4.22Å; M105-K157 HydrophobicContact SD-CD 3.88Å; M105-K166 HydrophobicContact CE-CB 3.72Å; M105-K166 HydrophobicContact CE-CD 3.88Å; M105-K166 HydrophobicContact CE-CG 3.75Å; M105-K166 HydrophobicContact SD-CD 4.09Å
106E92Very high91.7Very high93 Ų9326.5 Ų26.544%0.43514%0.141SC..  trans-100.2-7.6-171.5-62.4-171124.900113.4R47 M104 G108 K157 N159R47-E106 IonicContact CZ-OE1 3.29Å; R47-E106 IonicContact NH1-OE1 3.46Å; R47-E106 PolarHBondContact NH1-OE1 3.16Å; R47-E106 IonicContact NH2-OE1 2.75Å; M104-E106 HydrophobicContact CB-CG 4.34Å; M104-E106 HydrophobicContact CE-CG 4.35Å; E106-G108 VanDerWaalsContact C-N 3.27Å; E106-G108 PolarHBondContact O-N 3.17Å; E106-K157 PolarHBondContact N-O 2.91Å; E106-N159 PolarHBondContact O-ND2 3.45Å
107G90.5Very high91Very high2 Ų226.3 Ų26.32%0.02113%0.131CC..SBendtrans-79.4-6.9179.100000114.5R113 F156 D158G107-R113 WeakPolarHBondContact O-CD 3.3Å; G107-F156 WeakPolarHBondContact CA-O 3.5Å; G107-F156 PolarHBondContact N-O 3.3Å; G107-D158 VanDerWaalsContact CA-C 3.43Å; G107-D158 WeakPolarHBondContact CA-O 3.3Å
108G90.4Very high89.9Confident25 Ų2535.3 Ų35.326%0.25817%0.165SC..EExtended strand (participates in β ladder)trans75.8-176179.300000114.2E106 L155 F156E106-G108 VanDerWaalsContact C-N 3.27Å; E106-G108 PolarHBondContact O-N 3.17Å; G108-L155 WeakPolarHBondContact O-CA 3.45Å; G108-F156 PolarHBondContact O-N 3.24Å
109E91.1Very high89.3Confident68 Ų6840.7 Ų40.732%0.31819%0.19SC..EExtended strand (participates in β ladder)trans-73.8151-178.7-63171.2-165.200112.2F111 H112 R113 L155 Q330E109-F111 PolarHBondContact O-N 3.34Å; E109-H112 HydrophobicContact CB-CB 4.28Å; E109-H112 WeakPolarHBondContact O-CB 3.45Å; E109-H112 PolarHBondContact O-N 2.91Å; E109-H112 VanDerWaalsContact O-N 3.11Å; E109-R113 PolarHBondContact O-N 3.45Å; E109-L155 HydrophobicContact CB-CD2 4.35Å; E109-L155 HydrophobicContact CG-CD2 3.71Å; E109-Q330 PolarHBondContact OE2-NE2 2.97Å
110L91.5Very high89.1Confident0 Ų041.3 Ų41.30%019%0.193CC..Hα-helixtrans-48-55.1-175.8173.658.3000114.2R113 I114 V128 I132 L154 F156 I230 M234L110-R113 WeakPolarHBondContact O-CB 3.41Å; L110-R113 PolarHBondContact O-N 3.42Å; L110-I114 HydrophobicContact CD1-CD1 3.97Å; L110-I114 HydrophobicContact CG-CD1 4.35Å; L110-I114 WeakPolarHBondContact O-CG1 3.48Å; L110-I114 PolarHBondContact O-N 3.38Å; L110-I114 VanDerWaalsContact O-N 3.1Å; L110-V128 HydrophobicContact CD1-CG1 3.7Å; L110-V128 HydrophobicContact CD2-CG1 4.43Å; L110-I132 HydrophobicContact CD2-CD1 4.38Å; L110-L154 HydrophobicContact CB-CB 4.04Å; L110-L154 HydrophobicContact CD2-CB 4.39Å; L110-L154 HydrophobicContact CD2-CD1 3.8Å; L110-L154 PolarHBondContact N-O 3.16Å; L110-F156 HydrophobicContact CD1-CE2 3.77Å; L110-F156 HydrophobicContact CD1-CZ 4Å; L110-I230 HydrophobicContact CD2-CG2 3.79Å; L110-M234 HydrophobicContact CD1-SD 4.11Å; L110-M234 HydrophobicContact CD2-CG 4.33Å; L110-M234 HydrophobicContact CD2-SD 3.88Å; L110-M234 HydrophobicContact CG-SD 4.4Å
111F88.9Confident89Confident1 Ų142.2 Ų42.20%0.00420%0.199CC..Hα-helixtrans-75.1-27.7-177.4-64-22.4000113.2E109 R113 I114 S115 P151 I230 V233 M234 M320 V326 I329E109-F111 PolarHBondContact O-N 3.34Å; F111-R113 VanDerWaalsContact C-N 3.32Å; F111-I114 HydrophobicContact CD1-CD1 4.18Å; F111-I114 PolarHBondContact O-N 3.14Å; F111-S115 PolarHBondContact O-N 3.4Å; F111-S115 PolarHBondContact O-OG 2.95Å; F111-P151 HydrophobicContact CD2-CB 3.53Å; F111-P151 HydrophobicContact CD2-CG 3.49Å; F111-P151 VanDerWaalsContact CD2-CG 3.49Å; F111-P151 HydrophobicContact CE2-CB 3.61Å; F111-P151 HydrophobicContact CE2-CG 3.04Å; F111-P151 HydrophobicContact CG-CB 4.11Å; F111-P151 HydrophobicContact CG-CG 4.43Å; F111-P151 HydrophobicContact CZ-CB 4.22Å; F111-P151 HydrophobicContact CZ-CG 3.67Å; F111-I230 HydrophobicContact CZ-CG2 4.44Å; F111-V233 HydrophobicContact CD1-CG1 4.4Å; F111-V233 HydrophobicContact CD2-CG1 4.11Å; F111-V233 HydrophobicContact CE1-CB 4.28Å; F111-V233 HydrophobicContact CE1-CG1 3.75Å; F111-V233 HydrophobicContact CE2-CB 4.12Å; F111-V233 HydrophobicContact CE2-CG1 3.37Å; F111-V233 HydrophobicContact CZ-CB 3.61Å; F111-V233 HydrophobicContact CZ-CG1 3.2Å; F111-V233 HydrophobicContact CZ-CG2 4.48Å; F111-M234 HydrophobicContact CE1-CG 3.75Å; F111-M320 HydrophobicContact CB-CE 4.48Å; F111-M320 HydrophobicContact CB-SD 4.15Å; F111-M320 HydrophobicContact CD1-CE 3.97Å; F111-M320 HydrophobicContact CD1-SD 4.32Å; F111-M320 HydrophobicContact CD2-CE 4.37Å; F111-M320 HydrophobicContact CE1-CE 4.31Å; F111-M320 HydrophobicContact CG-CE 4.04Å; F111-M320 HydrophobicContact CG-SD 4.3Å; F111-V326 HydrophobicContact CB-CG1 4.04Å; F111-I329 HydrophobicContact CD2-CG2 4.28Å; F111-I329 HydrophobicContact CE2-CG2 3.93Å
112H86.9Confident88.8Confident66 Ų6642.2 Ų42.231%0.30620%0.199SC..Hα-helixtrans-65.8-39.1171.2-172.868.8000111.2E109 S115 Q116E109-H112 HydrophobicContact CB-CB 4.28Å; E109-H112 WeakPolarHBondContact O-CB 3.45Å; E109-H112 PolarHBondContact O-N 2.91Å; E109-H112 VanDerWaalsContact O-N 3.11Å; H112-S115 PolarHBondContact O-N 3.04Å; H112-S115 PolarHBondContact O-OG 2.9Å; H112-Q116 PolarHBondContact CD2-NE2 3.36Å; H112-Q116 PolarHBondContact NE2-NE2 3.42Å; H112-Q116 WeakPolarHBondContact O-CG 3.01Å; H112-Q116 PolarHBondContact O-N 2.86Å
113R87.9Confident88.6Confident22 Ų2245.7 Ų45.78%0.08321%0.213CC..Hα-helixtrans-63.5-45.6174.9-168.376.6174.5147.65.2110.9G107 E109 L110 F111 S115 Q116 H117 F156 N159 S160G107-R113 WeakPolarHBondContact O-CD 3.3Å; E109-R113 PolarHBondContact O-N 3.45Å; L110-R113 WeakPolarHBondContact O-CB 3.41Å; L110-R113 PolarHBondContact O-N 3.42Å; F111-R113 VanDerWaalsContact C-N 3.32Å; R113-S115 VanDerWaalsContact C-N 3.34Å; R113-S115 PolarHBondContact O-N 2.86Å; R113-Q116 PolarHBondContact O-N 2.77Å; R113-H117 PolarHBondContact O-ND1 3.43Å; R113-F156 HydrophobicContact CB-CD2 3.59Å; R113-F156 HydrophobicContact CB-CE2 3.58Å; R113-F156 HydrophobicContact CG-CD2 3.61Å; R113-F156 HydrophobicContact CG-CE2 3.63Å; R113-F156 HydrophobicContact CG-CG 4.3Å; R113-F156 HydrophobicContact CG-CZ 4.36Å; R113-N159 PolarHBondContact NH1-OD1 2.82Å; R113-N159 PolarHBondContact NH2-O 3.46Å; R113-S160 PolarHBondContact NH2-O 3Å
114I88.1Confident88.4Confident4 Ų447.8 Ų47.82%0.02122%0.223CC..Hα-helixtrans-61.1-42.8178.5-69.1169000111L110 F111 Q116 H117 F120 M234 A317 M320L110-I114 HydrophobicContact CD1-CD1 3.97Å; L110-I114 HydrophobicContact CG-CD1 4.35Å; L110-I114 WeakPolarHBondContact O-CG1 3.48Å; L110-I114 PolarHBondContact O-N 3.38Å; L110-I114 VanDerWaalsContact O-N 3.1Å; F111-I114 HydrophobicContact CD1-CD1 4.18Å; F111-I114 PolarHBondContact O-N 3.14Å; I114-Q116 PolarHBondContact O-N 3.25Å; I114-H117 PolarHBondContact O-N 3.39Å; I114-H117 VanDerWaalsContact O-N 3.13Å; I114-F120 HydrophobicContact CD1-CD1 4.17Å; I114-F120 HydrophobicContact CD1-CE1 3.64Å; I114-F120 HydrophobicContact CD1-CE2 4.12Å; I114-F120 HydrophobicContact CD1-CZ 3.6Å; I114-F120 HydrophobicContact CG1-CD1 4.23Å; I114-F120 HydrophobicContact CG1-CD2 4.05Å; I114-F120 HydrophobicContact CG1-CE1 4.09Å; I114-F120 HydrophobicContact CG1-CE2 3.91Å; I114-F120 HydrophobicContact CG1-CG 4.21Å; I114-F120 HydrophobicContact CG1-CZ 3.92Å; I114-F120 HydrophobicContact CG2-CB 4.25Å; I114-F120 HydrophobicContact CG2-CD1 4Å; I114-F120 HydrophobicContact CG2-CG 4.08Å; I114-M234 HydrophobicContact CD1-CG 3.92Å; I114-M234 HydrophobicContact CD1-SD 4.42Å; I114-A317 HydrophobicContact CG2-CB 4.48Å; I114-M320 HydrophobicContact CB-SD 4.39Å; I114-M320 HydrophobicContact CG2-SD 3.97Å
115S84.9Confident88.4Confident19 Ų1947 Ų4713%0.13322%0.219CC..Hα-helixtrans-67.3-21179.868.80000114.9F111 H112 R113 M320F111-S115 PolarHBondContact O-N 3.4Å; F111-S115 PolarHBondContact O-OG 2.95Å; H112-S115 PolarHBondContact O-N 3.04Å; H112-S115 PolarHBondContact O-OG 2.9Å; R113-S115 VanDerWaalsContact C-N 3.34Å; R113-S115 PolarHBondContact O-N 2.86Å; S115-M320 WeakPolarHBondContact CB-O 3.38Å
116Q83.8Confident88.5Confident107 Ų10746 Ų4650%0.522%0.216SC..Hα-helixtrans-80.3-19.4175.1-71.9179.4-15.400113.3H112 R113 I114H112-Q116 PolarHBondContact CD2-NE2 3.36Å; H112-Q116 PolarHBondContact NE2-NE2 3.42Å; H112-Q116 WeakPolarHBondContact O-CG 3.01Å; H112-Q116 PolarHBondContact O-N 2.86Å; R113-Q116 PolarHBondContact O-N 2.77Å; I114-Q116 PolarHBondContact O-N 3.25Å
117H78.8Confident88.5Confident49 Ų4946.5 Ų46.523%0.22722%0.218CC..  trans-95.3130.7-177.4-69.969.8000110.1R113 I114 H119 A317R113-H117 PolarHBondContact O-ND1 3.43Å; I114-H117 PolarHBondContact O-N 3.39Å; I114-H117 VanDerWaalsContact O-N 3.13Å; H117-H119 PolarHBondContact O-N 3.26Å; H117-A317 WeakPolarHBondContact O-CB 3.28Å
118R71.6Confident88.7Confident203 Ų20347 Ų4777%0.76622%0.22SC*.SBendtrans-68.3-25.7176.4-169.6175.5178-171.60.1112.7
119H83Confident89.1Confident113 Ų11345.8 Ų45.852%0.52321%0.208SC..  trans-132.9117.6180-5596.2000109H117H117-H119 PolarHBondContact O-N 3.26Å
120F89.8Confident89.3Confident14 Ų1446.2 Ų46.26%0.06121%0.209CC..  trans-121.7125.6169.6-176.1-116.6000107.4I114 Q124 A125 M234 L314 A317I114-F120 HydrophobicContact CD1-CD1 4.17Å; I114-F120 HydrophobicContact CD1-CE1 3.64Å; I114-F120 HydrophobicContact CD1-CE2 4.12Å; I114-F120 HydrophobicContact CD1-CZ 3.6Å; I114-F120 HydrophobicContact CG1-CD1 4.23Å; I114-F120 HydrophobicContact CG1-CD2 4.05Å; I114-F120 HydrophobicContact CG1-CE1 4.09Å; I114-F120 HydrophobicContact CG1-CE2 3.91Å; I114-F120 HydrophobicContact CG1-CG 4.21Å; I114-F120 HydrophobicContact CG1-CZ 3.92Å; I114-F120 HydrophobicContact CG2-CB 4.25Å; I114-F120 HydrophobicContact CG2-CD1 4Å; I114-F120 HydrophobicContact CG2-CG 4.08Å; F120-Q124 HydrophobicContact CD2-CB 3.91Å; F120-Q124 HydrophobicContact CE2-CB 3.62Å; F120-Q124 HydrophobicContact CZ-CB 4.35Å; F120-A125 HydrophobicContact CE1-CB 3.74Å; F120-A125 HydrophobicContact CZ-CB 3.84Å; F120-M234 HydrophobicContact CE1-CB 4.26Å; F120-L314 HydrophobicContact CD1-CB 4.42Å; F120-L314 HydrophobicContact CD1-CD1 3.6Å; F120-L314 HydrophobicContact CE1-CD1 3.75Å; F120-L314 WeakPolarHBondContact O-CB 3.49Å; F120-L314 PolarHBondContact O-N 2.82Å; F120-A317 HydrophobicContact CB-CB 3.94Å
121T92.3Very high89.6Confident22 Ų2248.5 Ų48.514%0.13522%0.219CC..BIsolated β-bridgetrans-104.8158.9-171.957.60000111.9K123 Q124 A125 N312T121-K123 PolarHBondContact O-N 3.38Å; T121-Q124 WeakPolarHBondContact O-CB 3.27Å; T121-Q124 PolarHBondContact O-N 3.49Å; T121-Q124 VanDerWaalsContact O-N 3.1Å; T121-Q124 VanDerWaalsContact OG1-CG 3.28Å; T121-Q124 WeakPolarHBondContact OG1-CG 3.23Å; T121-Q124 PolarHBondContact OG1-N 2.7Å; T121-Q124 PolarHBondContact OG1-OE1 2.61Å; T121-A125 PolarHBondContact O-N 3.19Å; T121-N312 CarbonylContact C-O 3.48Å; T121-N312 VanDerWaalsContact CA-O 3.24Å; T121-N312 WeakPolarHBondContact CA-O 3.37Å
122E93.3Very high90Very high0 Ų048.6 Ų48.60%022%0.22CC..Hα-helixtrans-59.5-36.1175.8-168.6-178.2144.400112.1A125 S126 L235 S274 A277 W303 L310 N312 L314E122-A125 WeakPolarHBondContact O-CB 3.36Å; E122-A125 PolarHBondContact O-N 3.38Å; E122-S126 PolarHBondContact O-N 3.05Å; E122-L235 HydrophobicContact CG-CD2 4.11Å; E122-S274 VanDerWaalsContact OE1-CB 3.23Å; E122-S274 WeakPolarHBondContact OE1-CB 3.34Å; E122-S274 PolarHBondContact OE1-OG 3.13Å; E122-S274 PolarHBondContact OE2-N 3.43Å; E122-A277 WeakPolarHBondContact OE1-CB 3.37Å; E122-W303 HydrophobicContact CG-CZ2 4.3Å; E122-W303 PolarHBondContact OE1-NE1 2.96Å; E122-L310 CarbonylContact C-O 3.5Å; E122-L310 HydrophobicContact CB-CB 4.08Å; E122-L310 WeakPolarHBondContact CB-O 3.37Å; E122-L310 HydrophobicContact CG-CB 4.25Å; E122-L310 HydrophobicContact CG-CD1 4.48Å; E122-L310 PolarHBondContact N-O 3.38Å; E122-N312 PolarHBondContact N-O 3.35Å; E122-L314 HydrophobicContact CB-CD2 4Å; E122-L314 HydrophobicContact CB-CG 4.35Å; E122-L314 HydrophobicContact CG-CD2 4.45Å
123K91.8Very high90.6Very high89 Ų8945.4 Ų45.439%0.38721%0.205SC..Hα-helixtrans-60.5-44.1172.8-175.1174.7-177.5176.40112.5T121 S126 Q127 L310 D311T121-K123 PolarHBondContact O-N 3.38Å; K123-S126 PolarHBondContact O-N 2.93Å; K123-Q127 VanDerWaalsContact O-CG 3.31Å; K123-Q127 WeakPolarHBondContact O-CG 3.29Å; K123-Q127 PolarHBondContact O-N 3Å; K123-L310 HydrophobicContact CB-CB 4.23Å; K123-L310 WeakPolarHBondContact CB-O 3.47Å; K123-L310 PolarHBondContact N-O 3.34Å; K123-D311 VanDerWaalsContact CD-OD1 3.25Å; K123-D311 WeakPolarHBondContact CD-OD1 3.33Å
124Q91.9Very high91Very high59 Ų5946.4 Ų46.428%0.27621%0.212SC..Hα-helixtrans-64-41.5174.8-72.7167.3-50.300111.2F120 T121 S126 Q127 V128F120-Q124 HydrophobicContact CD2-CB 3.91Å; F120-Q124 HydrophobicContact CE2-CB 3.62Å; F120-Q124 HydrophobicContact CZ-CB 4.35Å; T121-Q124 WeakPolarHBondContact O-CB 3.27Å; T121-Q124 PolarHBondContact O-N 3.49Å; T121-Q124 VanDerWaalsContact O-N 3.1Å; T121-Q124 VanDerWaalsContact OG1-CG 3.28Å; T121-Q124 WeakPolarHBondContact OG1-CG 3.23Å; T121-Q124 PolarHBondContact OG1-N 2.7Å; T121-Q124 PolarHBondContact OG1-OE1 2.61Å; Q124-S126 VanDerWaalsContact C-N 3.35Å; Q124-S126 PolarHBondContact O-N 3.5Å; Q124-Q127 PolarHBondContact O-N 3.18Å; Q124-V128 WeakPolarHBondContact O-CG2 2.8Å; Q124-V128 PolarHBondContact O-N 3.01Å
125A94Very high91.5Very high0 Ų046.2 Ų46.20%021%0.211CC..Hα-helixtrans-61.1-41.5175.600000112.6F120 T121 E122 T129 M234 L235 W303 L314F120-A125 HydrophobicContact CE1-CB 3.74Å; F120-A125 HydrophobicContact CZ-CB 3.84Å; T121-A125 PolarHBondContact O-N 3.19Å; E122-A125 WeakPolarHBondContact O-CB 3.36Å; E122-A125 PolarHBondContact O-N 3.38Å; A125-T129 WeakPolarHBondContact O-CB 3.49Å; A125-T129 PolarHBondContact O-N 2.82Å; A125-T129 PolarHBondContact O-OG1 3.47Å; A125-M234 HydrophobicContact CB-CB 4.49Å; A125-L235 HydrophobicContact CB-CD2 4.32Å; A125-W303 HydrophobicContact CB-CH2 4.37Å; A125-W303 HydrophobicContact CB-CZ2 4.29Å; A125-L314 HydrophobicContact CB-CD1 3.82Å
126S95.1Very high92.1Very high11 Ų1145.3 Ų45.38%0.07721%0.205CC..Hα-helixtrans-62.5-46174.41700000111.9E122 K123 Q124 V128 T129 K130 W303E122-S126 PolarHBondContact O-N 3.05Å; K123-S126 PolarHBondContact O-N 2.93Å; Q124-S126 VanDerWaalsContact C-N 3.35Å; Q124-S126 PolarHBondContact O-N 3.5Å; S126-V128 PolarHBondContact O-N 2.64Å; S126-T129 WeakPolarHBondContact O-CB 3.48Å; S126-T129 PolarHBondContact O-N 2.79Å; S126-K130 WeakPolarHBondContact O-CB 3.24Å; S126-K130 PolarHBondContact O-N 3.08Å; S126-W303 PolarHBondContact OG-O 2.68Å
127Q93.5Very high92.6Very high103 Ų10344.1 Ų44.148%0.48120%0.196SC..Hα-helixtrans-62.1-44.5177.5-73.2172.7-17.900112.7K123 Q124 T129 K130 Q131K123-Q127 VanDerWaalsContact O-CG 3.31Å; K123-Q127 WeakPolarHBondContact O-CG 3.29Å; K123-Q127 PolarHBondContact O-N 3Å; Q124-Q127 PolarHBondContact O-N 3.18Å; Q127-T129 VanDerWaalsContact C-N 3.33Å; Q127-K130 PolarHBondContact O-N 2.44Å; Q127-Q131 PolarHBondContact O-N 3.46Å; Q127-Q131 VanDerWaalsContact O-N 3.16Å
128V95.2Very high93.4Very high11 Ų1143.6 Ų43.67%0.06719%0.193CC..Hα-helixtrans-61.6-44.6174.9169.20000110.2L110 Q124 S126 K130 Q131 I132 F156 V165 M234L110-V128 HydrophobicContact CD1-CG1 3.7Å; L110-V128 HydrophobicContact CD2-CG1 4.43Å; Q124-V128 WeakPolarHBondContact O-CG2 2.8Å; Q124-V128 PolarHBondContact O-N 3.01Å; S126-V128 PolarHBondContact O-N 2.64Å; V128-K130 VanDerWaalsContact C-N 3.33Å; V128-K130 PolarHBondContact O-N 3.25Å; V128-Q131 PolarHBondContact O-N 3.18Å; V128-I132 HydrophobicContact CG1-CD1 3.82Å; V128-I132 WeakPolarHBondContact O-CG1 3.4Å; V128-I132 PolarHBondContact O-N 3.23Å; V128-F156 HydrophobicContact CG2-CE1 4.48Å; V128-F156 HydrophobicContact CG2-CZ 4.11Å; V128-V165 HydrophobicContact CG1-CG1 4.22Å; V128-M234 HydrophobicContact CB-SD 4.32Å; V128-M234 HydrophobicContact CG1-CE 4.45Å; V128-M234 HydrophobicContact CG1-SD 3.76Å
129T96.9Very high94.4Very high0 Ų034 Ų340%016%0.157CC..Hα-helixtrans-60.5-42.7177.8-610000111.5A125 S126 Q127 Q131 I132 A133 L227 I231 M234 W303 L304A125-T129 WeakPolarHBondContact O-CB 3.49Å; A125-T129 PolarHBondContact O-N 2.82Å; A125-T129 PolarHBondContact O-OG1 3.47Å; S126-T129 WeakPolarHBondContact O-CB 3.48Å; S126-T129 PolarHBondContact O-N 2.79Å; Q127-T129 VanDerWaalsContact C-N 3.33Å; T129-Q131 VanDerWaalsContact C-N 3.33Å; T129-Q131 PolarHBondContact O-N 2.84Å; T129-I132 PolarHBondContact O-N 3.03Å; T129-A133 VanDerWaalsContact O-CB 3.3Å; T129-A133 WeakPolarHBondContact O-CB 3.36Å; T129-A133 PolarHBondContact O-N 3.18Å; T129-L227 HydrophobicContact CG2-CD1 4.31Å; T129-I231 HydrophobicContact CG2-CD1 3.61Å; T129-I231 HydrophobicContact CG2-CG1 3.84Å; T129-M234 WeakPolarHBondContact OG1-CE 3.44Å; T129-W303 HydrophobicContact CG2-CZ3 3.93Å; T129-L304 HydrophobicContact CG2-CD1 4.44Å; T129-L304 HydrophobicContact CG2-CD2 4.32Å
130K96.8Very high94.8Very high77 Ų7729.2 Ų29.234%0.33514%0.135SC..Hα-helixtrans-59.4-44177.6-171.6167.3-172.4155.70111.7S126 Q127 V128 A133 L134 L299 L304 N305S126-K130 WeakPolarHBondContact O-CB 3.24Å; S126-K130 PolarHBondContact O-N 3.08Å; Q127-K130 PolarHBondContact O-N 2.44Å; V128-K130 VanDerWaalsContact C-N 3.33Å; V128-K130 PolarHBondContact O-N 3.25Å; K130-A133 PolarHBondContact O-N 3.36Å; K130-L134 HydrophobicContact CG-CD1 4.38Å; K130-L134 WeakPolarHBondContact O-CB 3.08Å; K130-L134 VanDerWaalsContact O-CG 3.24Å; K130-L134 WeakPolarHBondContact O-CG 3.31Å; K130-L134 PolarHBondContact O-N 3.23Å; K130-L299 HydrophobicContact CG-CD2 4.48Å; K130-L304 HydrophobicContact CB-CD2 4.05Å; K130-L304 HydrophobicContact CG-CD2 4.38Å; K130-L304 PolarHBondContact NZ-O 3Å; K130-N305 PolarHBondContact NZ-OD1 2.72Å
131Q97.4Very high94.7Very high48 Ų4834.2 Ų34.222%0.22416%0.162CC..Hα-helixtrans-63.1-42.8176.3-72.6-174.656.300112.7N74 Q127 V128 T129 L134 A135 P164 V165N74-Q131 WeakPolarHBondContact CB-O 3.29Å; N74-Q131 WeakPolarHBondContact ND2-CB 3.26Å; N74-Q131 PolarHBondContact ND2-OE1 3.33Å; Q127-Q131 PolarHBondContact O-N 3.46Å; Q127-Q131 VanDerWaalsContact O-N 3.16Å; V128-Q131 PolarHBondContact O-N 3.18Å; T129-Q131 VanDerWaalsContact C-N 3.33Å; T129-Q131 PolarHBondContact O-N 2.84Å; Q131-L134 PolarHBondContact O-N 3.29Å; Q131-A135 PolarHBondContact O-N 2.9Å; Q131-A135 VanDerWaalsContact O-N 3.14Å; Q131-P164 VanDerWaalsContact OE1-CA 3.25Å; Q131-V165 HydrophobicContact CB-CG1 3.41Å; Q131-V165 VanDerWaalsContact CB-CG1 3.41Å; Q131-V165 HydrophobicContact CG-CG1 4.29Å
132I98.1Very high94.5Very high3 Ų336.2 Ų36.22%0.01517%0.171CC..Hα-helixtrans-63.8-44.4175.4-60.1162.5000110.4L110 V128 T129 L134 A135 L136 L149 L154 V165 L227L110-I132 HydrophobicContact CD2-CD1 4.38Å; V128-I132 HydrophobicContact CG1-CD1 3.82Å; V128-I132 WeakPolarHBondContact O-CG1 3.4Å; V128-I132 PolarHBondContact O-N 3.23Å; T129-I132 PolarHBondContact O-N 3.03Å; I132-L134 VanDerWaalsContact C-N 3.34Å; I132-L134 PolarHBondContact O-N 3.25Å; I132-A135 WeakPolarHBondContact O-CB 3.23Å; I132-A135 PolarHBondContact O-N 3.48Å; I132-L136 HydrophobicContact CG2-CD1 4.21Å; I132-L136 HydrophobicContact CG2-CG 4.48Å; I132-L136 WeakPolarHBondContact O-CG 3.03Å; I132-L136 PolarHBondContact O-N 3.24Å; I132-L149 HydrophobicContact CG2-CD1 4.15Å; I132-L149 HydrophobicContact CG2-CD2 4.46Å; I132-L154 HydrophobicContact CD1-CD1 3.64Å; I132-L154 HydrophobicContact CD1-CD2 4.36Å; I132-L154 HydrophobicContact CG1-CD1 4.17Å; I132-L154 HydrophobicContact CG1-CD2 3.96Å; I132-L154 HydrophobicContact CG2-CD2 4.23Å; I132-V165 HydrophobicContact CG1-CG1 4.12Å; I132-L227 HydrophobicContact CB-CD1 4.23Å; I132-L227 HydrophobicContact CG2-CD1 3.74Å
133A97.8Very high94.1Very high0 Ų039.9 Ų39.90%019%0.191CC..Hα-helixtrans-63.9-38179.400000112T129 K130 L136 R137 L227 I295 V298 L299T129-A133 VanDerWaalsContact O-CB 3.3Å; T129-A133 WeakPolarHBondContact O-CB 3.36Å; T129-A133 PolarHBondContact O-N 3.18Å; K130-A133 PolarHBondContact O-N 3.36Å; A133-L136 PolarHBondContact O-N 3.27Å; A133-R137 WeakPolarHBondContact O-CB 3.33Å; A133-R137 PolarHBondContact O-N 2.88Å; A133-L227 HydrophobicContact CB-CD2 4.5Å; A133-I295 HydrophobicContact CB-CD1 4.02Å; A133-I295 WeakPolarHBondContact O-CD1 3.4Å; A133-V298 HydrophobicContact CB-CG1 4.06Å; A133-L299 HydrophobicContact CB-CD2 3.69Å; A133-L299 HydrophobicContact CB-CG 4.1Å
134L98Very high93.8Very high43 Ų4335.6 Ų35.623%0.22517%0.172CC..Hα-helixtrans-63.3-43.3173.9-72.2169.9000111.9K130 Q131 I132 R137 H138 L299K130-L134 HydrophobicContact CG-CD1 4.38Å; K130-L134 WeakPolarHBondContact O-CB 3.08Å; K130-L134 VanDerWaalsContact O-CG 3.24Å; K130-L134 WeakPolarHBondContact O-CG 3.31Å; K130-L134 PolarHBondContact O-N 3.23Å; Q131-L134 PolarHBondContact O-N 3.29Å; I132-L134 VanDerWaalsContact C-N 3.34Å; I132-L134 PolarHBondContact O-N 3.25Å; L134-R137 PolarHBondContact O-N 2.62Å; L134-H138 PolarHBondContact O-N 3.01Å; L134-L299 HydrophobicContact CD2-CD1 4.33Å; L134-L299 HydrophobicContact CD2-CD2 3.97Å; L134-L299 HydrophobicContact CG-CD2 4.06Å
135A97.9Very high93.6Very high0 Ų032.8 Ų32.80%016%0.159CC..Hα-helixtrans-59.9-47.217400000111.9N74 I75 Q131 I132 H138 C139 L167N74-A135 HydrophobicContact CB-CB 3.86Å; N74-A135 WeakPolarHBondContact O-CB 3.36Å; I75-A135 HydrophobicContact CD1-CB 4.35Å; I75-A135 HydrophobicContact CG1-CB 3.86Å; Q131-A135 PolarHBondContact O-N 2.9Å; Q131-A135 VanDerWaalsContact O-N 3.14Å; I132-A135 WeakPolarHBondContact O-CB 3.23Å; I132-A135 PolarHBondContact O-N 3.48Å; A135-H138 PolarHBondContact O-N 2.7Å; A135-C139 PolarHBondContact O-N 3.02Å; A135-C139 VanDerWaalsContact O-N 3.12Å; A135-C139 PolarHBondContact O-SG 2.82Å; A135-L167 HydrophobicContact CB-CB 4.31Å
136L96.2Very high93.4Very high0 Ų032.8 Ų32.80%016%0.159CC..Hα-helixtrans-64.2-41.8178-70.5175.4000112.1I132 A133 H138 C139 H140 H146 L149 L167 D223 L227 I295I132-L136 HydrophobicContact CG2-CD1 4.21Å; I132-L136 HydrophobicContact CG2-CG 4.48Å; I132-L136 WeakPolarHBondContact O-CG 3.03Å; I132-L136 PolarHBondContact O-N 3.24Å; A133-L136 PolarHBondContact O-N 3.27Å; L136-H138 VanDerWaalsContact C-N 3.31Å; L136-H138 PolarHBondContact O-N 3.44Å; L136-C139 WeakPolarHBondContact O-CB 3.44Å; L136-C139 PolarHBondContact O-N 3.46Å; L136-H140 WeakPolarHBondContact O-CB 3.29Å; L136-H140 PolarHBondContact O-CD2 3.41Å; L136-H140 VanDerWaalsContact O-CD2 3.26Å; L136-H140 VanDerWaalsContact O-CG 3.22Å; L136-H140 PolarHBondContact O-N 3.13Å; L136-H146 HydrophobicContact CD2-CB 4.47Å; L136-L149 HydrophobicContact CD1-CD2 3.74Å; L136-L149 HydrophobicContact CD2-CD1 4.4Å; L136-L149 HydrophobicContact CD2-CD2 4.4Å; L136-L167 HydrophobicContact CD2-CD2 4.27Å; L136-D223 HydrophobicContact CD1-CB 4.47Å; L136-D223 HydrophobicContact CD2-CB 4.03Å; L136-L227 HydrophobicContact CD1-CB 4.47Å; L136-L227 HydrophobicContact CD1-CD2 4.26Å; L136-I295 HydrophobicContact CB-CD1 3.89Å; L136-I295 HydrophobicContact CB-CG1 4.42Å; L136-I295 HydrophobicContact CD1-CD1 4.47Å
137R95.6Very high93Very high82 Ų8233.1 Ų33.131%0.30916%0.158SC..Hα-helixtrans-57.1-47.6175.6-178.5178.665-179.17.2110.4A133 L134 C139 H140 L141 I295 E296 L299A133-R137 WeakPolarHBondContact O-CB 3.33Å; A133-R137 PolarHBondContact O-N 2.88Å; L134-R137 PolarHBondContact O-N 2.62Å; R137-C139 PolarHBondContact O-N 2.55Å; R137-H140 PolarHBondContact O-N 2.92Å; R137-H140 VanDerWaalsContact O-N 3.15Å; R137-L141 HydrophobicContact CG-CD1 3.92Å; R137-L141 HydrophobicContact CG-CG 4.16Å; R137-L141 WeakPolarHBondContact O-CB 3.45Å; R137-L141 VanDerWaalsContact O-CG 3.3Å; R137-L141 WeakPolarHBondContact O-CG 3.14Å; R137-L141 PolarHBondContact O-N 2.82Å; R137-I295 HydrophobicContact CB-CG1 3.78Å; R137-I295 HydrophobicContact CB-CG2 4.44Å; R137-I295 HydrophobicContact CG-CG2 4.41Å; R137-E296 WeakPolarHBondContact CD-OE1 3.46Å; R137-E296 WeakPolarHBondContact CD-OE2 3.25Å; R137-E296 VanDerWaalsContact CG-OE1 3.28Å; R137-E296 WeakPolarHBondContact CG-OE1 3.29Å; R137-E296 IonicContact NH1-OE2 2.97Å; R137-L299 HydrophobicContact CB-CD1 3.97Å; R137-L299 VanDerWaalsContact CD-CD1 3.49Å; R137-L299 HydrophobicContact CG-CD1 4.24Å
138H95.7Very high92.6Very high38 Ų3828.3 Ų28.318%0.17614%0.136CC..Hα-helixtrans-57.3-48.8178.2-18076.9000111.8C69 H72 L134 A135 L136 H140 L141 L142C69-H138 PolarHBondContact O-NE2 3.42Å; H72-H138 HydrophobicContact CB-CB 4.22Å; H72-H138 AromaticContact CD2-CG 3.76Å; H72-H138 AromaticContact CG-CG 3.95Å; L134-H138 PolarHBondContact O-N 3.01Å; A135-H138 PolarHBondContact O-N 2.7Å; L136-H138 VanDerWaalsContact C-N 3.31Å; L136-H138 PolarHBondContact O-N 3.44Å; H138-H140 PolarHBondContact O-N 3.35Å; H138-L141 PolarHBondContact O-N 2.8Å; H138-L142 PolarHBondContact O-N 3.05Å
139C93Very high92.2Very high0 Ų027.8 Ų27.80%013%0.133CC..Hα-helixtrans-56.9-48.4173.5-66.60000111.6C69 A135 L136 R137 L141 L142 N143 I144C69-C139 VanDerWaalsContact SG-SG 3.65Å; A135-C139 PolarHBondContact O-N 3.02Å; A135-C139 VanDerWaalsContact O-N 3.12Å; A135-C139 PolarHBondContact O-SG 2.82Å; L136-C139 WeakPolarHBondContact O-CB 3.44Å; L136-C139 PolarHBondContact O-N 3.46Å; R137-C139 PolarHBondContact O-N 2.55Å; C139-L141 VanDerWaalsContact C-N 3.34Å; C139-L141 PolarHBondContact O-N 3.18Å; C139-L142 CarbonylContact O-C 3.58Å; C139-L142 PolarHBondContact O-N 3.43Å; C139-L142 VanDerWaalsContact O-N 3.12Å; C139-N143 PolarHBondContact O-N 3.24Å; C139-I144 CarbonylContact C-O 3.44Å; C139-I144 HydrophobicContact CB-CB 4.41Å; C139-I144 WeakPolarHBondContact CB-O 3.43Å; C139-I144 WeakPolarHBondContact O-CA 3.36Å; C139-I144 WeakPolarHBondContact O-CB 3.31Å; C139-I144 PolarHBondContact O-N 3.35Å; C139-I144 VanDerWaalsContact O-O 3.09Å
140H90Very high91.6Very high14 Ų1428.7 Ų28.77%0.06514%0.137CC..Hα-helixtrans-67-32.3-174.9-72.2-168.6000113L136 R137 H138 L142 N143 I144 K220 D223L136-H140 WeakPolarHBondContact O-CB 3.29Å; L136-H140 PolarHBondContact O-CD2 3.41Å; L136-H140 VanDerWaalsContact O-CD2 3.26Å; L136-H140 VanDerWaalsContact O-CG 3.22Å; L136-H140 PolarHBondContact O-N 3.13Å; R137-H140 PolarHBondContact O-N 2.92Å; R137-H140 VanDerWaalsContact O-N 3.15Å; H138-H140 PolarHBondContact O-N 3.35Å; H140-L142 VanDerWaalsContact C-N 3.34Å; H140-N143 WeakPolarHBondContact O-CA 3.35Å; H140-N143 PolarHBondContact O-N 3.02Å; H140-N143 VanDerWaalsContact O-N 3.08Å; H140-I144 PolarHBondContact CD2-O 3.06Å; H140-I144 PolarHBondContact N-O 3.41Å; H140-K220 HydrophobicContact CB-CD 4.18Å; H140-K220 PolarHBondContact O-NZ 2.92Å; H140-D223 IonicContact CD2-OD2 3.52Å; H140-D223 IonicContact CE1-OD2 3.77Å; H140-D223 IonicContact NE2-OD2 2.63Å; H140-D223 PolarHBondContact NE2-OD2 3.12Å
141L88.9Confident90.9Very high119 Ų11925 Ų2562%0.62312%0.121SC*.Hα-helixtrans-67.1-33.7172.8-73.9173000112.2R137 H138 C139 N143R137-L141 HydrophobicContact CG-CD1 3.92Å; R137-L141 HydrophobicContact CG-CG 4.16Å; R137-L141 WeakPolarHBondContact O-CB 3.45Å; R137-L141 VanDerWaalsContact O-CG 3.3Å; R137-L141 WeakPolarHBondContact O-CG 3.14Å; R137-L141 PolarHBondContact O-N 2.82Å; H138-L141 PolarHBondContact O-N 2.8Å; C139-L141 VanDerWaalsContact C-N 3.34Å; C139-L141 PolarHBondContact O-N 3.18Å; L141-N143 PolarHBondContact O-N 3.16Å
142L86.9Confident90.3Very high64 Ų6424.9 Ų24.934%0.33512%0.12SC..THydrogen-bonded Turntrans-79.37.9170.6-63175.6000112.9M68 H138 C139 H140 I144M68-L142 WeakPolarHBondContact O-CD1 3.5Å; H138-L142 PolarHBondContact O-N 3.05Å; C139-L142 CarbonylContact O-C 3.58Å; C139-L142 PolarHBondContact O-N 3.43Å; C139-L142 VanDerWaalsContact O-N 3.12Å; H140-L142 VanDerWaalsContact C-N 3.34Å; L142-I144 HydrophobicContact CB-CD1 4.03Å; L142-I144 HydrophobicContact CB-CG1 4.25Å; L142-I144 PolarHBondContact O-N 2.87Å
143N85.3Confident89.9Confident76 Ų7625.1 Ų25.141%0.40612%0.122SC..THydrogen-bonded Turntrans55.334.6-171.4-68.4-47.6000113.3C139 H140 L141 I175 D176 K220C139-N143 PolarHBondContact O-N 3.24Å; H140-N143 WeakPolarHBondContact O-CA 3.35Å; H140-N143 PolarHBondContact O-N 3.02Å; H140-N143 VanDerWaalsContact O-N 3.08Å; L141-N143 PolarHBondContact O-N 3.16Å; N143-I175 HydrophobicContact CB-CG2 4.45Å; N143-I175 CarbonylContact O-C 3.57Å; N143-I175 VanDerWaalsContact O-CA 3.29Å; N143-I175 WeakPolarHBondContact O-CA 3.31Å; N143-D176 PolarHBondContact O-N 3.34Å; N143-K220 PolarHBondContact OD1-NZ 2.9Å
144I86.3Confident89.7Confident0 Ų025.2 Ų25.20%012%0.122CC..EExtended strand (participates in β ladder)trans-107.5122.4175.3-63.3169.4000108.2L65 M68 C69 C139 H140 L142 A173 K174 I175L65-I144 HydrophobicContact CB-CD1 4.49Å; L65-I144 HydrophobicContact CD2-CD1 3.89Å; L65-I144 HydrophobicContact CD2-CG1 4.1Å; M68-I144 HydrophobicContact CB-CD1 4.14Å; M68-I144 HydrophobicContact CE-CD1 4.25Å; M68-I144 HydrophobicContact SD-CD1 4.25Å; C69-I144 VanDerWaalsContact SG-CD1 3.58Å; C139-I144 CarbonylContact C-O 3.44Å; C139-I144 HydrophobicContact CB-CB 4.41Å; C139-I144 WeakPolarHBondContact CB-O 3.43Å; C139-I144 WeakPolarHBondContact O-CA 3.36Å; C139-I144 WeakPolarHBondContact O-CB 3.31Å; C139-I144 PolarHBondContact O-N 3.35Å; C139-I144 VanDerWaalsContact O-O 3.09Å; H140-I144 PolarHBondContact CD2-O 3.06Å; H140-I144 PolarHBondContact N-O 3.41Å; L142-I144 HydrophobicContact CB-CD1 4.03Å; L142-I144 HydrophobicContact CB-CG1 4.25Å; L142-I144 PolarHBondContact O-N 2.87Å; I144-A173 HydrophobicContact CG2-CB 4.22Å; I144-K174 WeakPolarHBondContact CA-O 3.32Å; I144-I175 HydrophobicContact CG1-CG1 4.32Å
145A87.9Confident89.5Confident0 Ų024.9 Ų24.90%012%0.12CC..EExtended strand (participates in β ladder)trans-97.1134.6167.900000109.2R147 A173 K174 N219 K220A145-R147 HydrophobicContact CB-CG 4.18Å; A145-A173 VanDerWaalsContact O-CA 3.23Å; A145-A173 WeakPolarHBondContact O-CA 3.16Å; A145-K174 PolarHBondContact N-O 2.82Å; A145-K174 PolarHBondContact O-N 2.91Å; A145-N219 HydrophobicContact CB-CB 3.53Å; A145-K220 HydrophobicContact CB-CG 4.22Å
146H89.1Confident89.4Confident0 Ų025.9 Ų25.90%013%0.125CC..  trans-75.3-41.9-176.5-174.9-93.9000111.9L136 D148 L149 L167 C168 D169 F172 A173 D223L136-H146 HydrophobicContact CD2-CB 4.47Å; H146-D148 VanDerWaalsContact CE1-C 3.44Å; H146-D148 PolarHBondContact CE1-O 2.98Å; H146-D148 PolarHBondContact ND1-N 3.41Å; H146-D148 PolarHBondContact ND1-O 3.06Å; H146-D148 PolarHBondContact O-N 2.86Å; H146-L149 PolarHBondContact ND1-N 3.24Å; H146-L167 HydrophobicContact CB-CD2 4.46Å; H146-C168 PolarHBondContact NE2-O 3.14Å; H146-C168 VanDerWaalsContact NE2-O 3.17Å; H146-D169 PolarHBondContact CE1-O 2.9Å; H146-D169 PolarHBondContact NE2-O 3.2Å; H146-D169 VanDerWaalsContact NE2-O 3.09Å; H146-F172 CarbonylContact O-C 3.51Å; H146-A173 WeakPolarHBondContact O-CA 3.36Å; H146-A173 PolarHBondContact O-N 2.97Å; H146-D223 PolarHBondContact N-OD2 3.39Å
147R85.9Confident89.3Confident17 Ų1728.6 Ų28.66%0.06414%0.136CC..  trans62.8-8.8177.8-66.4170.725162.3-12.5116.5A145 F172 N219 D223 R341 D344A145-R147 HydrophobicContact CB-CG 4.18Å; R147-F172 HydrophobicContact CB-CB 4.37Å; R147-F172 PolarHBondContact NE-O 3.27Å; R147-F172 VanDerWaalsContact NE-O 3.1Å; R147-N219 HydrophobicContact CG-CB 4.34Å; R147-D223 WeakPolarHBondContact CA-OD1 3.36Å; R147-D223 PolarHBondContact N-OD1 3.34Å; R147-R341 VanDerWaalsContact O-CZ 3.24Å; R147-R341 PolarHBondContact O-NE 3.05Å; R147-R341 PolarHBondContact O-NH2 3.39Å; R147-D344 IonicContact CZ-OD2 3.94Å; R147-D344 IonicContact NH1-OD1 3.91Å; R147-D344 IonicContact NH1-OD2 3.88Å; R147-D344 PolarHBondContact NH1-OD2 3.11Å; R147-D344 VanDerWaalsContact NH1-OD2 3.07Å; R147-D344 IonicContact NH2-OD2 2.63Å; R147-D344 PolarHBondContact NH2-OD2 2.95Å
148D84.9Confident89.2Confident2 Ų227.4 Ų27.41%0.01114%0.136CC..  trans-125.741.8175.1-163.419.2000112.5H146 K150 N153 F172 R341H146-D148 VanDerWaalsContact CE1-C 3.44Å; H146-D148 PolarHBondContact CE1-O 2.98Å; H146-D148 PolarHBondContact ND1-N 3.41Å; H146-D148 PolarHBondContact ND1-O 3.06Å; H146-D148 PolarHBondContact O-N 2.86Å; D148-K150 PolarHBondContact O-N 3.25Å; D148-K150 VanDerWaalsContact O-N 3.12Å; D148-K150 WeakPolarHBondContact OD1-CD 3.32Å; D148-K150 IonicContact OD1-NZ 3.66Å; D148-K150 PolarHBondContact OD1-NZ 2.96Å; D148-K150 VanDerWaalsContact OD1-NZ 3.13Å; D148-K150 IonicContact OD2-NZ 3.46Å; D148-K150 PolarHBondContact OD2-NZ 2.93Å; D148-N153 PolarHBondContact O-ND2 2.86Å; D148-N153 PolarHBondContact OD2-ND2 3.02Å; D148-F172 HydrophobicContact CB-CB 4.04Å; D148-F172 HydrophobicContact CB-CD2 3.76Å; D148-F172 HydrophobicContact CB-CG 4.21Å; D148-F172 VanDerWaalsContact OD2-CD2 3.26Å; D148-F172 WeakPolarHBondContact OD2-CD2 3.44Å; D148-F172 WeakPolarHBondContact OD2-CE2 3.4Å; D148-R341 VanDerWaalsContact CB-NH2 3.29Å; D148-R341 IonicContact OD1-CZ 3.87Å; D148-R341 IonicContact OD1-NH1 3.56Å; D148-R341 IonicContact OD1-NH2 2.88Å; D148-R341 PolarHBondContact OD1-NH2 3.45Å; D148-R341 IonicContact OD2-NH1 3.59Å; D148-R341 IonicContact OD2-NH2 3.86Å
149L87.8Confident88.9Confident0 Ų030.3 Ų30.30%015%0.153CC..  trans-72.9104.9176.3-174.872.3000110I132 L136 H146 L154 L167 D223 S226 L227 I230 H333 L337I132-L149 HydrophobicContact CG2-CD1 4.15Å; I132-L149 HydrophobicContact CG2-CD2 4.46Å; L136-L149 HydrophobicContact CD1-CD2 3.74Å; L136-L149 HydrophobicContact CD2-CD1 4.4Å; L136-L149 HydrophobicContact CD2-CD2 4.4Å; H146-L149 PolarHBondContact ND1-N 3.24Å; L149-L154 HydrophobicContact CD1-CD1 4.42Å; L149-L154 HydrophobicContact CD1-CD2 4.06Å; L149-L154 HydrophobicContact CD1-CG 4.4Å; L149-L167 HydrophobicContact CD1-CD1 3.69Å; L149-D223 WeakPolarHBondContact CD2-O 3.45Å; L149-S226 VanDerWaalsContact O-CB 3.25Å; L149-S226 WeakPolarHBondContact O-CB 3.47Å; L149-S226 PolarHBondContact O-OG 3.11Å; L149-L227 HydrophobicContact CD2-CB 4.04Å; L149-I230 HydrophobicContact CD2-CD1 4.07Å; L149-I230 HydrophobicContact CG-CD1 3.77Å; L149-H333 PolarHBondContact O-CE1 2.82Å; L149-L337 WeakPolarHBondContact O-CD1 3.49Å
150K84.8Confident88.7Confident20 Ų2032.4 Ų32.49%0.08717%0.168CC..  trans-144.5162-179.364.3-178.3179.8-144.30110.5D148 E152 N153 L337D148-K150 PolarHBondContact O-N 3.25Å; D148-K150 VanDerWaalsContact O-N 3.12Å; D148-K150 WeakPolarHBondContact OD1-CD 3.32Å; D148-K150 IonicContact OD1-NZ 3.66Å; D148-K150 PolarHBondContact OD1-NZ 2.96Å; D148-K150 VanDerWaalsContact OD1-NZ 3.13Å; D148-K150 IonicContact OD2-NZ 3.46Å; D148-K150 PolarHBondContact OD2-NZ 2.93Å; K150-E152 VanDerWaalsContact CB-OE2 3.24Å; K150-E152 WeakPolarHBondContact CB-OE2 3.5Å; K150-E152 HydrophobicContact CD-CB 4.42Å; K150-E152 VanDerWaalsContact CD-OE2 3.24Å; K150-E152 WeakPolarHBondContact CD-OE2 3.5Å; K150-E152 HydrophobicContact CG-CB 4.34Å; K150-E152 WeakPolarHBondContact CG-OE2 3.5Å; K150-E152 PolarHBondContact O-N 2.92Å; K150-N153 WeakPolarHBondContact CE-ND2 3.44Å; K150-N153 HydrophobicContact CG-CB 4.11Å; K150-N153 PolarHBondContact O-N 3.28Å; K150-L337 HydrophobicContact CB-CD1 3.73Å
151P81.6Confident88.3Confident0 Ų038.8 Ų38.80%020%0.201CC..G310 helixtrans-55.5-35.3-176.2-25.834.2000114.1F111 N153 L154 H333F111-P151 HydrophobicContact CD2-CB 3.53Å; F111-P151 HydrophobicContact CD2-CG 3.49Å; F111-P151 VanDerWaalsContact CD2-CG 3.49Å; F111-P151 HydrophobicContact CE2-CB 3.61Å; F111-P151 HydrophobicContact CE2-CG 3.04Å; F111-P151 HydrophobicContact CG-CB 4.11Å; F111-P151 HydrophobicContact CG-CG 4.43Å; F111-P151 HydrophobicContact CZ-CB 4.22Å; F111-P151 HydrophobicContact CZ-CG 3.67Å; P151-N153 PolarHBondContact O-N 3.38Å; P151-L154 PolarHBondContact O-N 3.03Å; P151-L154 VanDerWaalsContact O-N 3.14Å; P151-H333 WeakPolarHBondContact CD-ND1 3.38Å
152E84.2Confident88.1Confident45 Ų4539.7 Ų39.721%0.2121%0.207CC..G310 helixtrans-67.4-22.3179.7-52.493.2138.700112.4K150 Q330K150-E152 VanDerWaalsContact CB-OE2 3.24Å; K150-E152 WeakPolarHBondContact CB-OE2 3.5Å; K150-E152 HydrophobicContact CD-CB 4.42Å; K150-E152 VanDerWaalsContact CD-OE2 3.24Å; K150-E152 WeakPolarHBondContact CD-OE2 3.5Å; K150-E152 HydrophobicContact CG-CB 4.34Å; K150-E152 WeakPolarHBondContact CG-OE2 3.5Å; K150-E152 PolarHBondContact O-N 2.92Å; E152-Q330 HydrophobicContact CG-CG 4.37Å; E152-Q330 WeakPolarHBondContact OE1-CB 3.4Å
153N90.3Very high88.4Confident8 Ų836.9 Ų36.94%0.04319%0.193CC..G310 helixtrans-96.56.6177.9-71.5-6.8000112.5D148 K150 P151 L167 C168D148-N153 PolarHBondContact O-ND2 2.86Å; D148-N153 PolarHBondContact OD2-ND2 3.02Å; K150-N153 WeakPolarHBondContact CE-ND2 3.44Å; K150-N153 HydrophobicContact CG-CB 4.11Å; K150-N153 PolarHBondContact O-N 3.28Å; P151-N153 PolarHBondContact O-N 3.38Å; N153-L167 HydrophobicContact CB-CD1 4.45Å; N153-L167 WeakPolarHBondContact O-CA 3.26Å; N153-C168 PolarHBondContact O-N 2.96Å
154L94Very high88.8Confident1 Ų135.4 Ų35.41%0.00519%0.187CC..EExtended strand (participates in β ladder)trans-117.7103.8177.7-66.8175.2000109.2L110 I132 L149 P151 V165 L167 I230L110-L154 HydrophobicContact CB-CB 4.04Å; L110-L154 HydrophobicContact CD2-CB 4.39Å; L110-L154 HydrophobicContact CD2-CD1 3.8Å; L110-L154 PolarHBondContact N-O 3.16Å; I132-L154 HydrophobicContact CD1-CD1 3.64Å; I132-L154 HydrophobicContact CD1-CD2 4.36Å; I132-L154 HydrophobicContact CG1-CD1 4.17Å; I132-L154 HydrophobicContact CG1-CD2 3.96Å; I132-L154 HydrophobicContact CG2-CD2 4.23Å; L149-L154 HydrophobicContact CD1-CD1 4.42Å; L149-L154 HydrophobicContact CD1-CD2 4.06Å; L149-L154 HydrophobicContact CD1-CG 4.4Å; P151-L154 PolarHBondContact O-N 3.03Å; P151-L154 VanDerWaalsContact O-N 3.14Å; L154-V165 HydrophobicContact CB-CG2 4.16Å; L154-V165 HydrophobicContact CD2-CG2 4.5Å; L154-L167 HydrophobicContact CD2-CB 4.41Å; L154-L167 HydrophobicContact CD2-CD1 4.02Å; L154-I230 HydrophobicContact CD1-CD1 3.83Å; L154-I230 HydrophobicContact CD1-CG2 4.32Å
155L93.9Very high89.3Confident36 Ų3635.5 Ų35.519%0.18819%0.188CC..EExtended strand (participates in β ladder)trans-115.1140.5-172.3-55.7179.3000111M105 G108 E109 V165 K166M105-L155 HydrophobicContact CB-CB 3.93Å; M105-L155 HydrophobicContact CB-CD1 3.91Å; M105-L155 HydrophobicContact CE-CB 3.9Å; M105-L155 VanDerWaalsContact CE-O 3.23Å; M105-L155 WeakPolarHBondContact CE-O 3.38Å; M105-L155 HydrophobicContact CG-CB 4.2Å; M105-L155 HydrophobicContact CG-CD1 4.08Å; G108-L155 WeakPolarHBondContact O-CA 3.45Å; E109-L155 HydrophobicContact CB-CD2 4.35Å; E109-L155 HydrophobicContact CG-CD2 3.71Å; L155-V165 WeakPolarHBondContact O-CA 3.42Å; L155-K166 PolarHBondContact N-O 3.12Å; L155-K166 PolarHBondContact O-N 3.24Å
156F95.2Very high89.8Confident21 Ų2136.2 Ų36.29%0.09219%0.191CC..EExtended strand (participates in β ladder)trans-82139.8168.5-76-79.6000110.7G107 G108 L110 R113 V128 D158 A163 V165G107-F156 WeakPolarHBondContact CA-O 3.5Å; G107-F156 PolarHBondContact N-O 3.3Å; G108-F156 PolarHBondContact O-N 3.24Å; L110-F156 HydrophobicContact CD1-CE2 3.77Å; L110-F156 HydrophobicContact CD1-CZ 4Å; R113-F156 HydrophobicContact CB-CD2 3.59Å; R113-F156 HydrophobicContact CB-CE2 3.58Å; R113-F156 HydrophobicContact CG-CD2 3.61Å; R113-F156 HydrophobicContact CG-CE2 3.63Å; R113-F156 HydrophobicContact CG-CG 4.3Å; R113-F156 HydrophobicContact CG-CZ 4.36Å; V128-F156 HydrophobicContact CG2-CE1 4.48Å; V128-F156 HydrophobicContact CG2-CZ 4.11Å; F156-D158 VanDerWaalsContact C-N 3.33Å; F156-D158 PolarHBondContact O-N 3.21Å; F156-A163 HydrophobicContact CB-CB 4.41Å; F156-A163 HydrophobicContact CD1-CB 4.08Å; F156-A163 VanDerWaalsContact CD1-O 3.32Å; F156-A163 WeakPolarHBondContact CD1-O 3.17Å; F156-V165 HydrophobicContact CD1-CB 4.31Å; F156-V165 HydrophobicContact CE1-CB 4.06Å; F156-V165 HydrophobicContact CZ-CB 4.45Å
157K94.3Very high90.1Very high57 Ų5736.3 Ų36.325%0.24819%0.192CC..SBendtrans-58.1-45.9-178.9178.859.5-178.5177.40112.2E103 M104 M105 E106 P164E103-K157 WeakPolarHBondContact OE2-CE 3.47Å; E103-K157 IonicContact OE2-NZ 2.77Å; E103-K157 PolarHBondContact OE2-NZ 3.09Å; M104-K157 WeakPolarHBondContact O-CD 3.12Å; M104-K157 PolarHBondContact O-NZ 3.17Å; M105-K157 VanDerWaalsContact CE-CA 3.49Å; M105-K157 HydrophobicContact CE-CB 4.22Å; M105-K157 HydrophobicContact SD-CD 3.88Å; E106-K157 PolarHBondContact N-O 2.91Å; K157-P164 HydrophobicContact CB-CG 3.85Å; K157-P164 PolarHBondContact N-O 3.36Å
158D93.1Very high90.4Very high57 Ų5736.3 Ų36.331%0.30519%0.194SC..SBendtrans-155.1-171.7-177.958.157.2000110.7G107 F156 S160 A163G107-D158 VanDerWaalsContact CA-C 3.43Å; G107-D158 WeakPolarHBondContact CA-O 3.3Å; F156-D158 VanDerWaalsContact C-N 3.33Å; F156-D158 PolarHBondContact O-N 3.21Å; D158-S160 VanDerWaalsContact C-N 3.35Å; D158-S160 WeakPolarHBondContact OD1-CB 3.44Å; D158-S160 PolarHBondContact OD1-N 2.8Å; D158-S160 PolarHBondContact OD1-OG 3.07Å; D158-A163 VanDerWaalsContact O-CB 3.31Å; D158-A163 WeakPolarHBondContact O-CB 3.44Å
159N89.6Confident90.4Very high99 Ų9937 Ų3753%0.52920%0.198SC..SBendtrans-90.111.2-176.8-67.8-60.5000114.3E106 R113E106-N159 PolarHBondContact O-ND2 3.45Å; R113-N159 PolarHBondContact NH1-OD1 2.82Å; R113-N159 PolarHBondContact NH2-O 3.46Å
160S89.6Confident90.4Very high44 Ų4437 Ų3731%0.30820%0.198SC..SBendtrans-67160.2170.265.60000111.4R113 D158 D162 A163R113-S160 PolarHBondContact NH2-O 3Å; D158-S160 VanDerWaalsContact C-N 3.35Å; D158-S160 WeakPolarHBondContact OD1-CB 3.44Å; D158-S160 PolarHBondContact OD1-N 2.8Å; D158-S160 PolarHBondContact OD1-OG 3.07Å; S160-D162 VanDerWaalsContact C-N 3.33Å; S160-D162 WeakPolarHBondContact CB-OD1 3.41Å; S160-D162 PolarHBondContact OG-OD1 3.4Å; S160-A163 WeakPolarHBondContact O-CB 3.44Å; S160-A163 WeakPolarHBondContact OG-CA 3.17Å; S160-A163 WeakPolarHBondContact OG-CB 3.5Å; S160-A163 PolarHBondContact OG-N 3.38Å; S160-A163 VanDerWaalsContact OG-N 3.13Å
161L80.5Confident90.4Very high148 Ų14836.5 Ų36.578%0.77520%0.198SC*.SBendtrans-74.2-29.4-179.7-72.1170.9000111.9
162D85.6Confident90.3Very high139 Ų13938.2 Ų38.274%0.74321%0.205SC*.SBendtrans-99.110.4179.659.7-38.5000112.8S160S160-D162 VanDerWaalsContact C-N 3.33Å; S160-D162 WeakPolarHBondContact CB-OD1 3.41Å; S160-D162 PolarHBondContact OG-OD1 3.4Å
163A92.1Very high90.3Very high4 Ų436.4 Ų36.43%0.03320%0.198CC..PPolyproline II helixtrans-51.2128.1179.100000110.9F156 D158 S160F156-A163 HydrophobicContact CB-CB 4.41Å; F156-A163 HydrophobicContact CD1-CB 4.08Å; F156-A163 VanDerWaalsContact CD1-O 3.32Å; F156-A163 WeakPolarHBondContact CD1-O 3.17Å; D158-A163 VanDerWaalsContact O-CB 3.31Å; D158-A163 WeakPolarHBondContact O-CB 3.44Å; S160-A163 WeakPolarHBondContact O-CB 3.44Å; S160-A163 WeakPolarHBondContact OG-CA 3.17Å; S160-A163 WeakPolarHBondContact OG-CB 3.5Å; S160-A163 PolarHBondContact OG-N 3.38Å; S160-A163 VanDerWaalsContact OG-N 3.13Å
164P95.1Very high89.9Confident45 Ų4539.5 Ų39.529%0.29221%0.211SC..PPolyproline II helixtrans-68.2141176.925.9-33000110.6Q131 K157Q131-P164 VanDerWaalsContact OE1-CA 3.25Å; K157-P164 HydrophobicContact CB-CG 3.85Å; K157-P164 PolarHBondContact N-O 3.36Å
165V96.5Very high89.4Confident2 Ų241.6 Ų41.61%0.01222%0.222CC..EExtended strand (participates in β ladder)trans-84.6135.5167.263.90000108.8N74 V128 Q131 I132 L154 L155 F156N74-V165 PolarHBondContact ND2-O 3.29Å; V128-V165 HydrophobicContact CG1-CG1 4.22Å; Q131-V165 HydrophobicContact CB-CG1 3.41Å; Q131-V165 VanDerWaalsContact CB-CG1 3.41Å; Q131-V165 HydrophobicContact CG-CG1 4.29Å; I132-V165 HydrophobicContact CG1-CG1 4.12Å; L154-V165 HydrophobicContact CB-CG2 4.16Å; L154-V165 HydrophobicContact CD2-CG2 4.5Å; L155-V165 WeakPolarHBondContact O-CA 3.42Å; F156-V165 HydrophobicContact CD1-CB 4.31Å; F156-V165 HydrophobicContact CE1-CB 4.06Å; F156-V165 HydrophobicContact CZ-CB 4.45Å
166K97.5Very high88.2Confident16 Ų1640.2 Ų40.27%0.0722%0.215CC..EExtended strand (participates in β ladder)trans-128.2139.9179-52.4-166.3177.7-158.70112P73 N74 V76 E103 M105 L155P73-K166 WeakPolarHBondContact O-CD 3.11Å; P73-K166 WeakPolarHBondContact O-CE 3.36Å; P73-K166 PolarHBondContact O-NZ 3.37Å; N74-K166 CarbonylContact O-C 3.5Å; N74-K166 VanDerWaalsContact O-CA 3.27Å; N74-K166 WeakPolarHBondContact O-CA 3.46Å; V76-K166 HydrophobicContact CG2-CB 3.9Å; E103-K166 WeakPolarHBondContact OE1-CD 3.5Å; E103-K166 IonicContact OE1-NZ 2.74Å; E103-K166 PolarHBondContact OE1-NZ 2.88Å; E103-K166 IonicContact OE2-NZ 3.5Å; E103-K166 PolarHBondContact OE2-NZ 2.9Å; M105-K166 HydrophobicContact CE-CB 3.72Å; M105-K166 HydrophobicContact CE-CD 3.88Å; M105-K166 HydrophobicContact CE-CG 3.75Å; M105-K166 HydrophobicContact SD-CD 4.09Å; L155-K166 PolarHBondContact N-O 3.12Å; L155-K166 PolarHBondContact O-N 3.24Å
167L96.2Very high86.6Confident2 Ų245.8 Ų45.81%0.0124%0.241CC..EExtended strand (participates in β ladder)trans-78.9135.9171.8-179.561.8000110.5N74 I75 V76 A135 L136 H146 L149 N153 L154N74-L167 PolarHBondContact O-N 2.73Å; I75-L167 HydrophobicContact CG1-CB 4.49Å; V76-L167 PolarHBondContact N-O 3.3Å; A135-L167 HydrophobicContact CB-CB 4.31Å; L136-L167 HydrophobicContact CD2-CD2 4.27Å; H146-L167 HydrophobicContact CB-CD2 4.46Å; L149-L167 HydrophobicContact CD1-CD1 3.69Å; N153-L167 HydrophobicContact CB-CD1 4.45Å; N153-L167 WeakPolarHBondContact O-CA 3.26Å; L154-L167 HydrophobicContact CD2-CB 4.41Å; L154-L167 HydrophobicContact CD2-CD1 4.02Å
168C91.5Very high84.5Confident17 Ų1744.4 Ų44.412%0.11524%0.244CC..  trans-132.4174.3175.5770000112V76 H146 N153V76-C168 HydrophobicContact CB-CB 4.1Å; V76-C168 HydrophobicContact CG2-CB 3.61Å; H146-C168 PolarHBondContact NE2-O 3.14Å; H146-C168 VanDerWaalsContact NE2-O 3.17Å; N153-C168 PolarHBondContact O-N 2.96Å
169D85.7Confident82.2Confident17 Ų1745 Ų459%0.09125%0.246CC..  trans65.380.1173.4-161.46.8000117S33 K51 H146 G171S33-D169 WeakPolarHBondContact CB-OD1 3.39Å; S33-D169 VanDerWaalsContact OG-CG 3.28Å; S33-D169 PolarHBondContact OG-OD1 3.29Å; S33-D169 PolarHBondContact OG-OD2 3.37Å; K51-D169 IonicContact NZ-OD1 2.71Å; K51-D169 PolarHBondContact NZ-OD1 3.06Å; H146-D169 PolarHBondContact CE1-O 2.9Å; H146-D169 PolarHBondContact NE2-O 3.2Å; H146-D169 VanDerWaalsContact NE2-O 3.09Å; D169-G171 PolarHBondContact O-N 3.28Å; D169-G171 PolarHBondContact OD1-N 3.05Å
170F87.9Confident80Confident0 Ų042.7 Ų42.70%023%0.234CC..  trans-82.217.8178.3-74.9-113.1000114E62 L65 H66 C69 I75 F172 A173E62-F170 HydrophobicContact CG-CB 4.34Å; L65-F170 HydrophobicContact CB-CD1 4.35Å; H66-F170 HydrophobicContact CB-CB 3.92Å; H66-F170 HydrophobicContact CB-CD1 4.35Å; H66-F170 HydrophobicContact CB-CD2 3.82Å; H66-F170 HydrophobicContact CB-CE2 4.48Å; H66-F170 HydrophobicContact CB-CG 3.77Å; H66-F170 AromaticContact CD2-CD2 3.67Å; H66-F170 AromaticContact CD2-CE2 3.63Å; H66-F170 AromaticContact CG-CD2 3.46Å; H66-F170 VanDerWaalsContact CG-CD2 3.46Å; H66-F170 AromaticContact CG-CE2 3.93Å; H66-F170 AromaticContact CG-CG 3.96Å; H66-F170 AromaticContact ND1-CD2 3.79Å; C69-F170 HydrophobicContact CB-CE1 3.86Å; C69-F170 HydrophobicContact CB-CZ 3.85Å; I75-F170 HydrophobicContact CD1-CZ 4.35Å; I75-F170 HydrophobicContact CG2-CE2 3.86Å; I75-F170 HydrophobicContact CG2-CZ 3.9Å; F170-F172 PolarHBondContact O-N 2.73Å; F170-A173 HydrophobicContact CB-CB 3.83Å; F170-A173 HydrophobicContact CD1-CB 3.65Å; F170-A173 HydrophobicContact CG-CB 4.14Å; F170-A173 VanDerWaalsContact O-CB 3.27Å; F170-A173 WeakPolarHBondContact O-CB 3.4Å; F170-A173 PolarHBondContact O-N 3.2Å
171G83.4Confident77.7Confident8 Ų844.8 Ų44.88%0.08224%0.24CC..THydrogen-bonded Turntrans-63.9-14.5-174.500000115.8K58 E62 D169K58-G171 WeakPolarHBondContact CE-O 3.04Å; E62-G171 VanDerWaalsContact OE2-CA 3.29Å; E62-G171 WeakPolarHBondContact OE2-CA 3.47Å; D169-G171 PolarHBondContact O-N 3.28Å; D169-G171 PolarHBondContact OD1-N 3.05Å
172F80.8Confident75.4Confident36 Ų3643.4 Ų43.416%0.15824%0.238CC..THydrogen-bonded Turntrans-115.51.2172.5-65.1-86.5000113.5I32 H146 R147 D148 F170 R341I32-F172 HydrophobicContact CD1-CZ 4.45Å; I32-F172 HydrophobicContact CG2-CE2 4.36Å; I32-F172 HydrophobicContact CG2-CZ 4.03Å; H146-F172 CarbonylContact O-C 3.51Å; R147-F172 HydrophobicContact CB-CB 4.37Å; R147-F172 PolarHBondContact NE-O 3.27Å; R147-F172 VanDerWaalsContact NE-O 3.1Å; D148-F172 HydrophobicContact CB-CB 4.04Å; D148-F172 HydrophobicContact CB-CD2 3.76Å; D148-F172 HydrophobicContact CB-CG 4.21Å; D148-F172 VanDerWaalsContact OD2-CD2 3.26Å; D148-F172 WeakPolarHBondContact OD2-CD2 3.44Å; D148-F172 WeakPolarHBondContact OD2-CE2 3.4Å; F170-F172 PolarHBondContact O-N 2.73Å; F172-R341 VanDerWaalsContact CE1-NH1 3.34Å; F172-R341 VanDerWaalsContact CG-NH1 3.28Å; F172-R341 VanDerWaalsContact CZ-NH1 3.26Å
173A83.8Confident73Confident8 Ų840.7 Ų40.77%0.06623%0.228CC..  trans-65.6147.9-178.700000110.6L65 I144 A145 H146 F170L65-A173 HydrophobicContact CB-CB 4.44Å; L65-A173 VanDerWaalsContact CD1-C 3.46Å; L65-A173 HydrophobicContact CD1-CB 3.91Å; L65-A173 VanDerWaalsContact CD1-O 3.26Å; L65-A173 WeakPolarHBondContact CD1-O 3.46Å; I144-A173 HydrophobicContact CG2-CB 4.22Å; A145-A173 VanDerWaalsContact O-CA 3.23Å; A145-A173 WeakPolarHBondContact O-CA 3.16Å; H146-A173 WeakPolarHBondContact O-CA 3.36Å; H146-A173 PolarHBondContact O-N 2.97Å; F170-A173 HydrophobicContact CB-CB 3.83Å; F170-A173 HydrophobicContact CD1-CB 3.65Å; F170-A173 HydrophobicContact CG-CB 4.14Å; F170-A173 VanDerWaalsContact O-CB 3.27Å; F170-A173 WeakPolarHBondContact O-CB 3.4Å; F170-A173 PolarHBondContact O-N 3.2Å
174K82.6Confident70.1Confident72 Ų7248.6 Ų48.631%0.31326%0.264SS..EExtended strand (participates in β ladder)trans-146.3141.3-177.9-168.8175.5179.4178.40110.2I144 A145 D176 D344I144-K174 WeakPolarHBondContact CA-O 3.32Å; A145-K174 PolarHBondContact N-O 2.82Å; A145-K174 PolarHBondContact O-N 2.91Å; K174-D176 PolarHBondContact O-N 3.32Å; K174-D344 IonicContact NZ-OD1 3.82Å; K174-D344 PolarHBondContact NZ-OD1 3.04Å
175I81.6Confident67.1Low45 Ų4555.6 Ų55.623%0.23129%0.29CS..EExtended strand (participates in β ladder)trans-68.6119164.5-55.1-173.6000107.5R64 L65 N143 I144 Q177R64-I175 VanDerWaalsContact NH2-CD1 3.32Å; L65-I175 HydrophobicContact CD2-CD1 3.92Å; L65-I175 HydrophobicContact CD2-CG1 3.47Å; L65-I175 VanDerWaalsContact CD2-CG1 3.47Å; N143-I175 HydrophobicContact CB-CG2 4.45Å; N143-I175 CarbonylContact O-C 3.57Å; N143-I175 VanDerWaalsContact O-CA 3.29Å; N143-I175 WeakPolarHBondContact O-CA 3.31Å; I144-I175 HydrophobicContact CG1-CG1 4.32Å; I175-Q177 HydrophobicContact CB-CG 4.45Å; I175-Q177 HydrophobicContact CG2-CG 3.8Å; I175-Q177 PolarHBondContact O-N 3.21Å
176D70Confident63.9Low7 Ų759.1 Ų59.14%0.03731%0.312CS..  trans-88.785.5177.7-17654.7000108.9N143 K174 G178 T217 N219 K220N143-D176 PolarHBondContact O-N 3.34Å; K174-D176 PolarHBondContact O-N 3.32Å; D176-G178 PolarHBondContact O-N 3.42Å; D176-T217 WeakPolarHBondContact OD1-CB 3.37Å; D176-T217 PolarHBondContact OD1-OG1 3.49Å; D176-T217 WeakPolarHBondContact OD2-CB 3.37Å; D176-T217 WeakPolarHBondContact OD2-CG2 3.31Å; D176-T217 PolarHBondContact OD2-OG1 3.28Å; D176-N219 PolarHBondContact OD1-ND2 3.35Å; D176-K220 VanDerWaalsContact OD2-CE 3.24Å; D176-K220 WeakPolarHBondContact OD2-CE 3.23Å
177Q61.3Low60.8Low138 Ų13863.4 Ų63.465%0.64534%0.341SS*.  trans-74.414.8-177-65.6177.4-25.900113.3I175 D179I175-Q177 HydrophobicContact CB-CG 4.45Å; I175-Q177 HydrophobicContact CG2-CG 3.8Å; I175-Q177 PolarHBondContact O-N 3.21Å; Q177-D179 HydrophobicContact CB-CB 4.08Å; Q177-D179 PolarHBondContact O-N 3.2Å; Q177-D179 PolarHBondContact OE1-OD2 3.1Å
178G51Low57.6Low29 Ų2972.8 Ų72.830%0.29938%0.378SS..SBendtrans697.1-162.800000112.9D176 L180D176-G178 PolarHBondContact O-N 3.42Å; G178-L180 PolarHBondContact O-N 3.31Å
179D43.3Very low55.1Low68 Ų6881.9 Ų81.936%0.36441%0.411SS..  trans-92.981.4-171.6-76.7-12.3000111.6Q177 M181Q177-D179 HydrophobicContact CB-CB 4.08Å; Q177-D179 PolarHBondContact O-N 3.2Å; Q177-D179 PolarHBondContact OE1-OD2 3.1Å; D179-M181 VanDerWaalsContact CA-N 3.33Å; D179-M181 HydrophobicContact CB-CB 3.74Å; D179-M181 HydrophobicContact CB-CG 4.18Å; D179-M181 PolarHBondContact O-N 2.91Å; D179-M181 WeakPolarHBondContact OD1-CB 3.44Å; D179-M181 WeakPolarHBondContact OD1-CG 3.45Å
180L44.9Very low52.7Low52 Ų5283.4 Ų83.427%0.27242%0.421SS..  trans-65.713.8137.3-88.4147.8000111.7G178 V194 A197G178-L180 PolarHBondContact O-N 3.31Å; L180-V194 HydrophobicContact CD2-CG1 4.03Å; L180-A197 HydrophobicContact CD1-CB 3.77Å
181M41Very low50.4Low88 Ų8885.1 Ų85.143%0.43344%0.435SS..  trans-92.77.9-157-71.8-75.7-61.800115.7D179D179-M181 VanDerWaalsContact CA-N 3.33Å; D179-M181 HydrophobicContact CB-CB 3.74Å; D179-M181 HydrophobicContact CB-CG 4.18Å; D179-M181 PolarHBondContact O-N 2.91Å; D179-M181 WeakPolarHBondContact OD1-CB 3.44Å; D179-M181 WeakPolarHBondContact OD1-CG 3.45Å
182T31.5Very low48.2Very low118 Ų11889.5 Ų89.572%0.72446%0.462SS*.  trans-143.987.6174.19.60000114.4
183P34.6Very low46.5Very low82 Ų8292.1 Ų92.153%0.53248%0.475SS..  trans-81110.814029.3-19.2000107.7F185P183-F185 PolarHBondContact O-N 3.07Å
184Q32.3Very low44.6Very low171 Ų17192.7 Ų92.780%0.79948%0.478SS*.  trans-64.995.1148.7-85.6-179.6-18.300106.5
185F30.8Very low42.7Very low192 Ų19293.7 Ų93.784%0.84249%0.486SS*.SBendtrans37.186.5161.1-57.2-82.8000117.8P183P183-F185 PolarHBondContact O-N 3.07Å
186T31.3Very low41.1Very low76 Ų7698.3 Ų98.347%0.46651%0.507SS..  trans-157.7101.6143.7-290000112Y188 Y189T186-Y188 VanDerWaalsContact C-N 3.34Å; T186-Y188 PolarHBondContact O-N 3.34Å; T186-Y189 HydrophobicContact CG2-CD2 4.41Å
187P31.6Very low40Very low105 Ų10599.7 Ų99.768%0.68252%0.519SS*.THydrogen-bonded Turntrans-77.5-4.3-172.426.9-32.1000116.2
188Y29.6Very low39.6Very low200 Ų20095.3 Ų95.378%0.78450%0.498SS*.THydrogen-bonded Turntrans-93.4-3-169-65.6-74.6000116.5T186T186-Y188 VanDerWaalsContact C-N 3.34Å; T186-Y188 PolarHBondContact O-N 3.34Å
189Y37.2Very low39.7Very low208 Ų208102.2 Ų102.282%0.81652%0.515SS*.SBendtrans-128.913-172.5-63.5-78.3000114.9T186T186-Y189 HydrophobicContact CG2-CD2 4.41Å
190V36.8Very low40.2Very low48 Ų48104.9 Ų104.929%0.29152%0.52SS..  trans-81.6124.3-175.2-178.10000110.1V194 L195V190-V194 HydrophobicContact CG1-CB 3.47Å; V190-V194 VanDerWaalsContact CG1-CB 3.47Å; V190-V194 HydrophobicContact CG1-CG1 3.41Å; V190-V194 VanDerWaalsContact CG1-CG1 3.41Å; V190-V194 HydrophobicContact CG1-CG2 4.42Å; V190-L195 HydrophobicContact CB-CD2 4.2Å; V190-L195 HydrophobicContact CB-CG 4.3Å; V190-L195 HydrophobicContact CG1-CD2 3.88Å; V190-L195 HydrophobicContact CG1-CG 3.85Å
191A40Very low40.4Very low37 Ų37105.1 Ų105.131%0.30652%0.52SS..  trans-64.9145.9179.200000111.5Q193 V194 L195A191-Q193 VanDerWaalsContact C-N 3.27Å; A191-Q193 PolarHBondContact O-N 3.32Å; A191-Q193 VanDerWaalsContact O-N 3.12Å; A191-V194 HydrophobicContact CB-CG2 4.39Å; A191-V194 WeakPolarHBondContact O-CB 3.15Å; A191-V194 PolarHBondContact O-N 3.16Å; A191-L195 PolarHBondContact O-N 3.31Å
192P36Very low40.9Very low99 Ų99107.4 Ų107.464%0.64353%0.529SS*.Hα-helixtrans-52.6-38.9-172.4-27.734.3000114.8V194 L195 E196P192-V194 PolarHBondContact O-N 3.4Å; P192-L195 PolarHBondContact O-N 2.94Å; P192-E196 PolarHBondContact O-N 3.09Å
193Q45.5Very low41.9Very low92 Ų92106.2 Ų106.243%0.4351%0.514SS..Hα-helixtrans-63.5-26.5177.865.4-85.222.100113.6A191 A197 Y218A191-Q193 VanDerWaalsContact C-N 3.27Å; A191-Q193 PolarHBondContact O-N 3.32Å; A191-Q193 VanDerWaalsContact O-N 3.12Å; Q193-A197 WeakPolarHBondContact O-CB 3.17Å; Q193-A197 PolarHBondContact O-N 2.79Å; Q193-Y218 HydrophobicContact CG-CE2 4.28Å
194V42.8Very low42.8Very low20 Ų20104.2 Ų104.212%0.12150%0.498CS..Hα-helixtrans-78-39.6177.4179.30000110.2L180 V190 A191 P192 E196 Q198 I342L180-V194 HydrophobicContact CD2-CG1 4.03Å; V190-V194 HydrophobicContact CG1-CB 3.47Å; V190-V194 VanDerWaalsContact CG1-CB 3.47Å; V190-V194 HydrophobicContact CG1-CG1 3.41Å; V190-V194 VanDerWaalsContact CG1-CG1 3.41Å; V190-V194 HydrophobicContact CG1-CG2 4.42Å; A191-V194 HydrophobicContact CB-CG2 4.39Å; A191-V194 WeakPolarHBondContact O-CB 3.15Å; A191-V194 PolarHBondContact O-N 3.16Å; P192-V194 PolarHBondContact O-N 3.4Å; V194-E196 VanDerWaalsContact C-N 3.34Å; V194-Q198 WeakPolarHBondContact O-CB 3.47Å; V194-Q198 WeakPolarHBondContact O-CG 3.49Å; V194-Q198 PolarHBondContact O-N 3.29Å; V194-I342 HydrophobicContact CG2-CD1 3.99Å; V194-I342 HydrophobicContact CG2-CG1 4.44Å
195L43.8Very low43.7Very low92 Ų92102.6 Ų102.648%0.48249%0.488SS..Hα-helixtrans-65.9-37.4175.4-66.8173.4000111.8V190 A191 P192 R199V190-L195 HydrophobicContact CB-CD2 4.2Å; V190-L195 HydrophobicContact CB-CG 4.3Å; V190-L195 HydrophobicContact CG1-CD2 3.88Å; V190-L195 HydrophobicContact CG1-CG 3.85Å; A191-L195 PolarHBondContact O-N 3.31Å; P192-L195 PolarHBondContact O-N 2.94Å; L195-R199 VanDerWaalsContact O-CB 3.28Å; L195-R199 WeakPolarHBondContact O-CB 3.49Å; L195-R199 PolarHBondContact O-N 3.08Å
196E47.2Very low44.8Very low143 Ų14396.8 Ų96.867%0.66847%0.471SS*.Hα-helixtrans-71.3-43.2179.3-169151-152.100112.3P192 V194 Q198 R199 R200P192-E196 PolarHBondContact O-N 3.09Å; V194-E196 VanDerWaalsContact C-N 3.34Å; E196-Q198 VanDerWaalsContact C-N 3.33Å; E196-Q198 PolarHBondContact O-N 3.38Å; E196-R199 PolarHBondContact O-N 2.9Å; E196-R200 PolarHBondContact O-N 2.97Å; E196-R200 VanDerWaalsContact O-N 3.09Å
197A48.5Very low45.7Very low35 Ų3596.2 Ų96.229%0.28948%0.48SS..Hα-helixtrans-61.5-39.7172.500000112.3L180 Q193 H201L180-A197 HydrophobicContact CD1-CB 3.77Å; Q193-A197 WeakPolarHBondContact O-CB 3.17Å; Q193-A197 PolarHBondContact O-N 2.79Å; A197-H201 PolarHBondContact O-N 3.25Å; A197-H201 VanDerWaalsContact O-N 3.16Å
198Q51.9Low46.7Very low46 Ų4696.8 Ų96.822%0.21548%0.476CS..Hα-helixtrans-65.7-45.5175.3-76.6171.9-14.900112.7V194 E196 R200 H201 Q202V194-Q198 WeakPolarHBondContact O-CB 3.47Å; V194-Q198 WeakPolarHBondContact O-CG 3.49Å; V194-Q198 PolarHBondContact O-N 3.29Å; E196-Q198 VanDerWaalsContact C-N 3.33Å; E196-Q198 PolarHBondContact O-N 3.38Å; Q198-R200 VanDerWaalsContact C-N 3.28Å; Q198-R200 PolarHBondContact O-N 3.4Å; Q198-H201 PolarHBondContact O-N 3.44Å; Q198-Q202 WeakPolarHBondContact O-CG 3.28Å; Q198-Q202 PolarHBondContact O-N 2.79Å; Q198-Q202 VanDerWaalsContact O-N 3.08Å
199R53Low47.4Very low175 Ų17589.5 Ų89.566%0.6645%0.45SS*.Hα-helixtrans-64.2-33.7-179.1-172.1-178.8-85.2174.9-7111.6L195 E196 K203L195-R199 VanDerWaalsContact O-CB 3.28Å; L195-R199 WeakPolarHBondContact O-CB 3.49Å; L195-R199 PolarHBondContact O-N 3.08Å; E196-R199 PolarHBondContact O-N 2.9Å; R199-K203 VanDerWaalsContact O-CG 3.31Å; R199-K203 WeakPolarHBondContact O-CG 3.35Å; R199-K203 PolarHBondContact O-N 3.45Å
200R53.4Low47.6Very low124 Ų12485.4 Ų85.447%0.46845%0.449SS..Hα-helixtrans-73.6-44.8176.5-167.9179175.4135.90.8112.5E196 Q198 Q202 K203 E204 I209E196-R200 PolarHBondContact O-N 2.97Å; E196-R200 VanDerWaalsContact O-N 3.09Å; Q198-R200 VanDerWaalsContact C-N 3.28Å; Q198-R200 PolarHBondContact O-N 3.4Å; R200-Q202 VanDerWaalsContact C-N 3.27Å; R200-Q202 PolarHBondContact O-N 2.91Å; R200-K203 CarbonylContact O-C 3.15Å; R200-K203 WeakPolarHBondContact O-CA 3.25Å; R200-K203 WeakPolarHBondContact O-CB 3.35Å; R200-K203 PolarHBondContact O-N 3.44Å; R200-E204 IonicContact NE-OE1 3.62Å; R200-E204 PolarHBondContact NE-OE1 2.93Å; R200-E204 PolarHBondContact O-N 3.39Å; R200-I209 HydrophobicContact CG-CD1 3.47Å; R200-I209 VanDerWaalsContact CG-CD1 3.47Å
201H50.4Low48.1Very low57 Ų5788.3 Ų88.326%0.26447%0.467SS..Hα-helixtrans-59.8-37.8175.9-170.457.1000112.6A197 Q198 K203 E204 K205A197-H201 PolarHBondContact O-N 3.25Å; A197-H201 VanDerWaalsContact O-N 3.16Å; Q198-H201 PolarHBondContact O-N 3.44Å; H201-K203 VanDerWaalsContact C-N 3.31Å; H201-K203 PolarHBondContact O-N 2.75Å; H201-E204 PolarHBondContact O-N 2.97Å; H201-K205 VanDerWaalsContact NE2-CE 3.33Å; H201-K205 WeakPolarHBondContact NE2-CE 3.48Å; H201-K205 WeakPolarHBondContact O-CB 3.35Å; H201-K205 PolarHBondContact O-N 2.87Å
202Q50.2Low48.3Very low135 Ų13589.1 Ų89.163%0.63147%0.47SS*.Hα-helixtrans-63.1-37.7172.1-74.11762.100112.1Q198 R200 S206Q198-Q202 WeakPolarHBondContact O-CG 3.28Å; Q198-Q202 PolarHBondContact O-N 2.79Å; Q198-Q202 VanDerWaalsContact O-N 3.08Å; R200-Q202 VanDerWaalsContact C-N 3.27Å; R200-Q202 PolarHBondContact O-N 2.91Å; Q202-S206 VanDerWaalsContact O-CB 3.29Å; Q202-S206 WeakPolarHBondContact O-CB 3.38Å; Q202-S206 PolarHBondContact O-N 2.98Å; Q202-S206 PolarHBondContact O-OG 3.29Å
203K52.7Low48.5Very low93 Ų9390.6 Ų90.640%0.40448%0.48SS..Hα-helixtrans-70.7-35.1174.7-70.3176.1177.4-170.30112.7R199 R200 H201 S206 G207 I208 I209R199-K203 VanDerWaalsContact O-CG 3.31Å; R199-K203 WeakPolarHBondContact O-CG 3.35Å; R199-K203 PolarHBondContact O-N 3.45Å; R200-K203 CarbonylContact O-C 3.15Å; R200-K203 WeakPolarHBondContact O-CA 3.25Å; R200-K203 WeakPolarHBondContact O-CB 3.35Å; R200-K203 PolarHBondContact O-N 3.44Å; H201-K203 VanDerWaalsContact C-N 3.31Å; H201-K203 PolarHBondContact O-N 2.75Å; K203-S206 VanDerWaalsContact CA-OG 3.31Å; K203-S206 WeakPolarHBondContact CA-OG 3.45Å; K203-S206 PolarHBondContact O-OG 3.37Å; K203-G207 PolarHBondContact O-N 2.9Å; K203-I208 HydrophobicContact CB-CB 4.14Å; K203-I208 HydrophobicContact CB-CG2 4.39Å; K203-I208 HydrophobicContact CG-CB 4.43Å; K203-I208 HydrophobicContact CG-CD1 4.48Å; K203-I208 HydrophobicContact CG-CG2 4.34Å; K203-I208 PolarHBondContact O-N 3.45Å; K203-I209 HydrophobicContact CB-CD1 3.8Å; K203-I209 HydrophobicContact CB-CG1 3.77Å; K203-I209 PolarHBondContact O-N 3.01Å
204E53.2Low48.3Very low41 Ų4190.5 Ų90.519%0.19249%0.486CS..Hα-helixtrans-68-45.4173.9-72.3171.5-168.200111.3R200 H201 S206 G207 I209R200-E204 IonicContact NE-OE1 3.62Å; R200-E204 PolarHBondContact NE-OE1 2.93Å; R200-E204 PolarHBondContact O-N 3.39Å; H201-E204 PolarHBondContact O-N 2.97Å; E204-S206 VanDerWaalsContact C-N 3.34Å; E204-S206 PolarHBondContact O-N 2.87Å; E204-G207 PolarHBondContact O-N 3.32Å; E204-I209 HydrophobicContact CB-CG1 4.36Å; E204-I209 HydrophobicContact CG-CD1 3.58Å; E204-I209 HydrophobicContact CG-CG1 3.56Å
205K52.2Low48.6Very low137 Ų13794.4 Ų94.460%0.59651%0.512SS*.Hα-helixtrans-67.2-30.4176.4-80.6-174.3171.5178.60114.1H201 G207H201-K205 VanDerWaalsContact NE2-CE 3.33Å; H201-K205 WeakPolarHBondContact NE2-CE 3.48Å; H201-K205 WeakPolarHBondContact O-CB 3.35Å; H201-K205 PolarHBondContact O-N 2.87Å; K205-G207 VanDerWaalsContact C-N 3.27Å
206S54.5Low49Very low70 Ų7093.4 Ų93.449%0.4950%0.502SS..THydrogen-bonded Turntrans-84.81.5175.253.20000113.3Q202 K203 E204 I208Q202-S206 VanDerWaalsContact O-CB 3.29Å; Q202-S206 WeakPolarHBondContact O-CB 3.38Å; Q202-S206 PolarHBondContact O-N 2.98Å; Q202-S206 PolarHBondContact O-OG 3.29Å; K203-S206 VanDerWaalsContact CA-OG 3.31Å; K203-S206 WeakPolarHBondContact CA-OG 3.45Å; K203-S206 PolarHBondContact O-OG 3.37Å; E204-S206 VanDerWaalsContact C-N 3.34Å; E204-S206 PolarHBondContact O-N 2.87Å; S206-I208 PolarHBondContact O-N 3.23Å; S206-I208 VanDerWaalsContact OG-CD1 3.23Å; S206-I208 WeakPolarHBondContact OG-CD1 3.35Å; S206-I208 WeakPolarHBondContact OG-CG1 3.47Å
207G50.1Low49.8Very low63 Ų6387.3 Ų87.365%0.64947%0.474SS*.THydrogen-bonded Turntrans7011.2-179.700000114.4K203 E204 K205 I209K203-G207 PolarHBondContact O-N 2.9Å; E204-G207 PolarHBondContact O-N 3.32Å; K205-G207 VanDerWaalsContact C-N 3.27Å; G207-I209 VanDerWaalsContact C-N 3.29Å
208I52.5Low50.6Low117 Ų11787.1 Ų87.160%0.647%0.467SS*.SBendtrans-71.5-27.5179.6-64174.8000111K203 S206K203-I208 HydrophobicContact CB-CB 4.14Å; K203-I208 HydrophobicContact CB-CG2 4.39Å; K203-I208 HydrophobicContact CG-CB 4.43Å; K203-I208 HydrophobicContact CG-CD1 4.48Å; K203-I208 HydrophobicContact CG-CG2 4.34Å; K203-I208 PolarHBondContact O-N 3.45Å; S206-I208 PolarHBondContact O-N 3.23Å; S206-I208 VanDerWaalsContact OG-CD1 3.23Å; S206-I208 WeakPolarHBondContact OG-CD1 3.35Å; S206-I208 WeakPolarHBondContact OG-CG1 3.47Å
209I43.3Very low51.6Low48 Ų4885.9 Ų85.925%0.24646%0.462CS..SBendtrans-132.1149.7173.354.2177.3000110.4R200 K203 E204 G207 T211R200-I209 HydrophobicContact CG-CD1 3.47Å; R200-I209 VanDerWaalsContact CG-CD1 3.47Å; K203-I209 HydrophobicContact CB-CD1 3.8Å; K203-I209 HydrophobicContact CB-CG1 3.77Å; K203-I209 PolarHBondContact O-N 3.01Å; E204-I209 HydrophobicContact CB-CG1 4.36Å; E204-I209 HydrophobicContact CG-CD1 3.58Å; E204-I209 HydrophobicContact CG-CG1 3.56Å; G207-I209 VanDerWaalsContact C-N 3.29Å; I209-T211 PolarHBondContact O-N 2.95Å
210P42.5Very low53Low122 Ų12279 Ų7979%0.79244%0.436SS*.PPolyproline II helixtrans-56.3131.5179.8-2231.7000111S212P210-S212 PolarHBondContact O-N 3.1Å
211T46.8Very low54.4Low108 Ų10873.1 Ų73.166%0.66341%0.414SS*.PPolyproline II helixtrans-64.8119.1174.3-16.70000107.9I209I209-T211 PolarHBondContact O-N 2.95Å
212S43.7Very low56Low54 Ų5470.7 Ų70.738%0.37840%0.404SS..PPolyproline II helixtrans-58.7127.2170.8173.40000108.1P210 T214P210-S212 PolarHBondContact O-N 3.1Å; S212-T214 PolarHBondContact O-N 3.26Å; S212-T214 VanDerWaalsContact O-N 3.08Å; S212-T214 PolarHBondContact OG-N 3.27Å; S212-T214 PolarHBondContact OG-O 2.77Å
213P39.5Very low57.8Low131 Ų13164.3 Ų64.385%0.85137%0.374SS*.SBendtrans-62.5-17.9179.923.6-31.7000112.4
214T42.3Very low59.7Low90 Ų9060 Ų6055%0.55236%0.356SS*.SBendtrans-113.7115.2171.1500000110.1S212 Y216S212-T214 PolarHBondContact O-N 3.26Å; S212-T214 VanDerWaalsContact O-N 3.08Å; S212-T214 PolarHBondContact OG-N 3.27Å; S212-T214 PolarHBondContact OG-O 2.77Å; T214-Y216 PolarHBondContact O-N 3.23Å
215P48.8Very low61.4Low101 Ų10158.4 Ų58.466%0.65635%0.347SS*.  trans-67.2106.6174.625-30.1000109.1
216Y52.9Low63.2Low72 Ų7251.9 Ų51.928%0.28232%0.319SS..  trans-91.9120.9178.9-173.4-91.3000109.4T214 S221 P289 R292 T294T214-Y216 PolarHBondContact O-N 3.23Å; Y216-S221 VanDerWaalsContact CZ-CB 3.46Å; Y216-S221 WeakPolarHBondContact OH-CB 3.47Å; Y216-P289 HydrophobicContact CD1-CB 4.48Å; Y216-P289 HydrophobicContact CE1-CB 3.53Å; Y216-P289 WeakPolarHBondContact CE1-O 3.2Å; Y216-P289 PolarHBondContact OH-O 3.04Å; Y216-R292 WeakPolarHBondContact OH-CB 3.35Å; Y216-T294 HydrophobicContact CD2-CG2 4.46Å
217T64Low65.1Low14 Ų1448.6 Ų48.69%0.08630%0.296CS..  trans-117.9150.2-172.866.60000112D176 N219 K220 S221D176-T217 WeakPolarHBondContact OD1-CB 3.37Å; D176-T217 PolarHBondContact OD1-OG1 3.49Å; D176-T217 WeakPolarHBondContact OD2-CB 3.37Å; D176-T217 WeakPolarHBondContact OD2-CG2 3.31Å; D176-T217 PolarHBondContact OD2-OG1 3.28Å; T217-N219 PolarHBondContact O-N 2.94Å; T217-K220 PolarHBondContact O-N 3.29Å; T217-S221 WeakPolarHBondContact O-CB 3.36Å; T217-S221 PolarHBondContact O-N 3.31Å
218Y65.6Low67.3Low32 Ų3245.6 Ų45.613%0.12527%0.265CS..Hα-helixtrans-53.5-41178.6-175.4-92.9000112.2Q193 S221 C222 M340 I342Q193-Y218 HydrophobicContact CG-CE2 4.28Å; Y218-S221 WeakPolarHBondContact O-CB 3.46Å; Y218-S221 PolarHBondContact O-N 2.97Å; Y218-S221 PolarHBondContact O-OG 3.38Å; Y218-C222 VanDerWaalsContact CE1-SG 3.56Å; Y218-C222 PolarHBondContact O-N 2.89Å; Y218-C222 VanDerWaalsContact O-N 3.09Å; Y218-C222 PolarHBondContact O-SG 2.95Å; Y218-M340 WeakPolarHBondContact CE1-O 3.09Å; Y218-M340 PolarHBondContact OH-O 2.92Å; Y218-I342 HydrophobicContact CD1-CD1 3.41Å; Y218-I342 VanDerWaalsContact CD1-CD1 3.41Å; Y218-I342 HydrophobicContact CD1-CG1 3.97Å; Y218-I342 HydrophobicContact CE1-CD1 3.5Å; Y218-I342 VanDerWaalsContact CE1-CD1 3.5Å; Y218-I342 HydrophobicContact CE1-CG1 3.53Å; Y218-I342 HydrophobicContact CG-CD1 4.03Å
219N71.6Confident69.1Low20 Ų2040 Ų4011%0.10724%0.237CC..Hα-helixtrans-65.9-48.4-176.5-60.1-52.3000112.4A145 R147 D176 T217 S221 C222A145-N219 HydrophobicContact CB-CB 3.53Å; R147-N219 HydrophobicContact CG-CB 4.34Å; D176-N219 PolarHBondContact OD1-ND2 3.35Å; T217-N219 PolarHBondContact O-N 2.94Å; N219-S221 VanDerWaalsContact C-N 3.26Å; N219-S221 PolarHBondContact O-N 3.19Å; N219-C222 WeakPolarHBondContact O-CB 3.47Å; N219-C222 PolarHBondContact O-N 3.11Å
220K83.6Confident71.4Confident29 Ų2937.8 Ų37.813%0.12623%0.225CC..Hα-helixtrans-64.9-34.9177-64.6-178.4-172.1-176.30111H140 N143 A145 D176 T217 C222 D223 L224H140-K220 HydrophobicContact CB-CD 4.18Å; H140-K220 PolarHBondContact O-NZ 2.92Å; N143-K220 PolarHBondContact OD1-NZ 2.9Å; A145-K220 HydrophobicContact CB-CG 4.22Å; D176-K220 VanDerWaalsContact OD2-CE 3.24Å; D176-K220 WeakPolarHBondContact OD2-CE 3.23Å; T217-K220 PolarHBondContact O-N 3.29Å; K220-C222 VanDerWaalsContact C-N 3.28Å; K220-C222 PolarHBondContact O-N 3.15Å; K220-D223 PolarHBondContact O-N 3.34Å; K220-L224 PolarHBondContact O-N 3.14Å
221S82.5Confident74Confident1 Ų132 Ų321%0.00719%0.187CC..Hα-helixtrans-61.6-34.3175.488.10000113.2Y216 T217 Y218 N219 D223 L224 W225 R292Y216-S221 VanDerWaalsContact CZ-CB 3.46Å; Y216-S221 WeakPolarHBondContact OH-CB 3.47Å; T217-S221 WeakPolarHBondContact O-CB 3.36Å; T217-S221 PolarHBondContact O-N 3.31Å; Y218-S221 WeakPolarHBondContact O-CB 3.46Å; Y218-S221 PolarHBondContact O-N 2.97Å; Y218-S221 PolarHBondContact O-OG 3.38Å; N219-S221 VanDerWaalsContact C-N 3.26Å; N219-S221 PolarHBondContact O-N 3.19Å; S221-D223 VanDerWaalsContact C-N 3.34Å; S221-L224 PolarHBondContact O-N 3.34Å; S221-W225 PolarHBondContact O-N 3.02Å; S221-R292 VanDerWaalsContact C-NH1 3.27Å; S221-R292 PolarHBondContact O-NH1 3.04Å; S221-R292 PolarHBondContact OG-NH1 2.86Å
222C82.6Confident76.2Confident7 Ų727 Ų275%0.04716%0.157CC..Hα-helixtrans-64-40.3177.6-67.80000111.3Y218 N219 K220 L224 W225 S226Y218-C222 VanDerWaalsContact CE1-SG 3.56Å; Y218-C222 PolarHBondContact O-N 2.89Å; Y218-C222 VanDerWaalsContact O-N 3.09Å; Y218-C222 PolarHBondContact O-SG 2.95Å; N219-C222 WeakPolarHBondContact O-CB 3.47Å; N219-C222 PolarHBondContact O-N 3.11Å; K220-C222 VanDerWaalsContact C-N 3.28Å; K220-C222 PolarHBondContact O-N 3.15Å; C222-L224 VanDerWaalsContact C-N 3.29Å; C222-L224 PolarHBondContact O-N 3.4Å; C222-W225 PolarHBondContact O-N 3.13Å; C222-S226 PolarHBondContact O-N 3.33Å; C222-S226 PolarHBondContact O-OG 3.3Å
223D88.4Confident78.4Confident1 Ų124.6 Ų24.61%0.00514%0.139CC..Hα-helixtrans-60.9-41.2176.2-65.4-26.2000111.1L136 H140 H146 R147 L149 K220 S221 S226 L227L136-D223 HydrophobicContact CD1-CB 4.47Å; L136-D223 HydrophobicContact CD2-CB 4.03Å; H140-D223 IonicContact CD2-OD2 3.52Å; H140-D223 IonicContact CE1-OD2 3.77Å; H140-D223 IonicContact NE2-OD2 2.63Å; H140-D223 PolarHBondContact NE2-OD2 3.12Å; H146-D223 PolarHBondContact N-OD2 3.39Å; R147-D223 WeakPolarHBondContact CA-OD1 3.36Å; R147-D223 PolarHBondContact N-OD1 3.34Å; L149-D223 WeakPolarHBondContact CD2-O 3.45Å; K220-D223 PolarHBondContact O-N 3.34Å; S221-D223 VanDerWaalsContact C-N 3.34Å; D223-S226 PolarHBondContact O-N 3.37Å; D223-L227 WeakPolarHBondContact O-CB 3.38Å; D223-L227 PolarHBondContact O-N 3.42Å
224L92.4Very high81Confident3 Ų318.3 Ų18.32%0.01610%0.099CC..Hα-helixtrans-70.1-36.4179.8-60.3175.9000112.3K220 S221 C222 L227 G228 L284 R292 L293 I295K220-L224 PolarHBondContact O-N 3.14Å; S221-L224 PolarHBondContact O-N 3.34Å; C222-L224 VanDerWaalsContact C-N 3.29Å; C222-L224 PolarHBondContact O-N 3.4Å; L224-L227 WeakPolarHBondContact O-CB 3.24Å; L224-L227 PolarHBondContact O-N 3.01Å; L224-G228 PolarHBondContact O-N 3.5Å; L224-L284 HydrophobicContact CB-CD2 3.95Å; L224-L284 WeakPolarHBondContact O-CD2 3.4Å; L224-R292 HydrophobicContact CB-CG 4.46Å; L224-L293 WeakPolarHBondContact CD1-O 3.49Å; L224-I295 HydrophobicContact CD2-CB 4.09Å; L224-I295 HydrophobicContact CD2-CD1 3.76Å; L224-I295 HydrophobicContact CD2-CG1 4.49Å
225W89.5Confident83.4Confident6 Ų614 Ų142%0.0237%0.073CC..Hα-helixtrans-61.6-48.5171.2177.2-79.2000111.3S221 C222 L227 G228 V229 F241 I258 L285 M340S221-W225 PolarHBondContact O-N 3.02Å; C222-W225 PolarHBondContact O-N 3.13Å; W225-L227 VanDerWaalsContact C-N 3.27Å; W225-L227 PolarHBondContact O-N 2.77Å; W225-G228 WeakPolarHBondContact O-CA 3.45Å; W225-G228 PolarHBondContact O-N 2.59Å; W225-V229 PolarHBondContact O-N 3.25Å; W225-F241 HydrophobicContact CH2-CE2 4.22Å; W225-F241 AromaticContact CH2-CZ 3.81Å; W225-F241 HydrophobicContact CH2-CZ 3.81Å; W225-F241 HydrophobicContact CZ2-CD2 4.47Å; W225-F241 AromaticContact CZ2-CE2 3.46Å; W225-F241 HydrophobicContact CZ2-CE2 3.46Å; W225-F241 VanDerWaalsContact CZ2-CE2 3.46Å; W225-F241 AromaticContact CZ2-CZ 3.53Å; W225-F241 HydrophobicContact CZ2-CZ 3.53Å; W225-I258 HydrophobicContact CZ2-CG2 4.16Å; W225-L285 HydrophobicContact CD2-CD2 3.94Å; W225-L285 HydrophobicContact CE3-CD2 4.22Å; W225-L285 HydrophobicContact CG-CD2 4.31Å; W225-L285 HydrophobicContact CZ2-CD2 4.4Å; W225-L285 HydrophobicContact CZ3-CB 4.49Å; W225-L285 WeakPolarHBondContact CZ3-O 3.49Å; W225-L285 WeakPolarHBondContact O-CD2 3.19Å; W225-M340 HydrophobicContact CB-CE 3.82Å; W225-M340 HydrophobicContact CD2-CE 3.82Å; W225-M340 HydrophobicContact CD2-SD 4.13Å; W225-M340 HydrophobicContact CG-CE 3.47Å; W225-M340 VanDerWaalsContact CG-CE 3.47Å; W225-M340 HydrophobicContact CG-SD 3.84Å; W225-M340 PolarHBondContact NE1-SD 3Å; W225-M340 VanDerWaalsContact NE1-SD 3.41Å
226S89.8Confident85.4Confident1 Ų19.2 Ų9.21%0.0074%0.041CC..Hα-helixtrans-60.4-37.3177.2-78.20000112.6L149 C222 D223 G228 V229 I230 H333 L337L149-S226 VanDerWaalsContact O-CB 3.25Å; L149-S226 WeakPolarHBondContact O-CB 3.47Å; L149-S226 PolarHBondContact O-OG 3.11Å; C222-S226 PolarHBondContact O-N 3.33Å; C222-S226 PolarHBondContact O-OG 3.3Å; D223-S226 PolarHBondContact O-N 3.37Å; S226-G228 VanDerWaalsContact C-N 3.33Å; S226-G228 PolarHBondContact O-N 2.76Å; S226-V229 PolarHBondContact O-N 2.87Å; S226-I230 WeakPolarHBondContact O-CD1 3.09Å; S226-I230 VanDerWaalsContact O-CG1 3.3Å; S226-I230 WeakPolarHBondContact O-CG1 3.36Å; S226-I230 PolarHBondContact O-N 3.11Å; S226-H333 PolarHBondContact OG-NE2 2.97Å; S226-L337 WeakPolarHBondContact OG-CD2 3.25Å
227L95.5Very high87Confident0 Ų05.9 Ų5.90%03%0.029CC..Hα-helixtrans-60.2-44.3172.6-176.462.2000110.9T129 I132 A133 L136 L149 D223 L224 W225 V229 I230 I231 L284 V298T129-L227 HydrophobicContact CG2-CD1 4.31Å; I132-L227 HydrophobicContact CB-CD1 4.23Å; I132-L227 HydrophobicContact CG2-CD1 3.74Å; A133-L227 HydrophobicContact CB-CD2 4.5Å; L136-L227 HydrophobicContact CD1-CB 4.47Å; L136-L227 HydrophobicContact CD1-CD2 4.26Å; L149-L227 HydrophobicContact CD2-CB 4.04Å; D223-L227 WeakPolarHBondContact O-CB 3.38Å; D223-L227 PolarHBondContact O-N 3.42Å; L224-L227 WeakPolarHBondContact O-CB 3.24Å; L224-L227 PolarHBondContact O-N 3.01Å; W225-L227 VanDerWaalsContact C-N 3.27Å; W225-L227 PolarHBondContact O-N 2.77Å; L227-V229 VanDerWaalsContact C-N 3.35Å; L227-V229 PolarHBondContact O-N 3.5Å; L227-I230 PolarHBondContact O-N 3.02Å; L227-I231 HydrophobicContact CD1-CD1 4.3Å; L227-I231 HydrophobicContact CD1-CG1 4.42Å; L227-I231 HydrophobicContact CG-CD1 3.89Å; L227-I231 HydrophobicContact CG-CG1 4.46Å; L227-I231 VanDerWaalsContact O-CG1 3.23Å; L227-I231 WeakPolarHBondContact O-CG1 3.34Å; L227-I231 PolarHBondContact O-N 3.04Å; L227-L284 HydrophobicContact CD2-CD1 4.4Å; L227-L284 HydrophobicContact CG-CD1 4.3Å; L227-V298 HydrophobicContact CD2-CG1 4.12Å; L227-V298 HydrophobicContact CD2-CG2 4.48Å
228G94.7Very high88Confident0 Ų07.7 Ų7.70%04%0.035CC..Hα-helixtrans-59.3-41.6174.800000113.4L224 W225 S226 I231 Y232L224-G228 PolarHBondContact O-N 3.5Å; W225-G228 WeakPolarHBondContact O-CA 3.45Å; W225-G228 PolarHBondContact O-N 2.59Å; S226-G228 VanDerWaalsContact C-N 3.33Å; S226-G228 PolarHBondContact O-N 2.76Å; G228-I231 PolarHBondContact O-N 3.22Å; G228-Y232 WeakPolarHBondContact O-CB 3.17Å; G228-Y232 PolarHBondContact O-N 3.19Å
229V90.6Very high88.8Confident1 Ų16.7 Ų6.71%0.0063%0.032CC..Hα-helixtrans-64.5-44.2175.3175.60000110.9W225 S226 L227 Y232 V233 P240 F241 L285W225-V229 PolarHBondContact O-N 3.25Å; S226-V229 PolarHBondContact O-N 2.87Å; L227-V229 VanDerWaalsContact C-N 3.35Å; L227-V229 PolarHBondContact O-N 3.5Å; V229-Y232 PolarHBondContact O-N 3.09Å; V229-V233 HydrophobicContact CG1-CG2 4.45Å; V229-V233 VanDerWaalsContact O-CG2 3.25Å; V229-V233 WeakPolarHBondContact O-CG2 3.24Å; V229-V233 PolarHBondContact O-N 3.13Å; V229-P240 HydrophobicContact CG1-CG 4.33Å; V229-P240 HydrophobicContact CG2-CG 4.2Å; V229-F241 HydrophobicContact CG2-CE2 4.42Å; V229-L285 HydrophobicContact CG2-CD2 3.86Å
230I92.8Very high89.2Confident0 Ų06.1 Ų6.10%03%0.029CC..Hα-helixtrans-63.4-44.2178.6-70.2160.6000110.8L110 F111 L149 L154 S226 L227 V233 M234L110-I230 HydrophobicContact CD2-CG2 3.79Å; F111-I230 HydrophobicContact CZ-CG2 4.44Å; L149-I230 HydrophobicContact CD2-CD1 4.07Å; L149-I230 HydrophobicContact CG-CD1 3.77Å; L154-I230 HydrophobicContact CD1-CD1 3.83Å; L154-I230 HydrophobicContact CD1-CG2 4.32Å; S226-I230 WeakPolarHBondContact O-CD1 3.09Å; S226-I230 VanDerWaalsContact O-CG1 3.3Å; S226-I230 WeakPolarHBondContact O-CG1 3.36Å; S226-I230 PolarHBondContact O-N 3.11Å; L227-I230 PolarHBondContact O-N 3.02Å; I230-V233 PolarHBondContact O-N 3.27Å; I230-M234 HydrophobicContact CG2-CE 4.04Å; I230-M234 HydrophobicContact CG2-CG 4.33Å; I230-M234 HydrophobicContact CG2-SD 4.35Å; I230-M234 WeakPolarHBondContact O-CB 3.07Å; I230-M234 WeakPolarHBondContact O-CG 3.45Å; I230-M234 PolarHBondContact O-N 3.21Å
231I95.6Very high88.8Confident0 Ų04.9 Ų4.90%02%0.024CC..Hα-helixtrans-60.6-49.6176.2-65.6162.4000110.3T129 L227 G228 V233 M234 L235 V280 V281 L284 W303T129-I231 HydrophobicContact CG2-CD1 3.61Å; T129-I231 HydrophobicContact CG2-CG1 3.84Å; L227-I231 HydrophobicContact CD1-CD1 4.3Å; L227-I231 HydrophobicContact CD1-CG1 4.42Å; L227-I231 HydrophobicContact CG-CD1 3.89Å; L227-I231 HydrophobicContact CG-CG1 4.46Å; L227-I231 VanDerWaalsContact O-CG1 3.23Å; L227-I231 WeakPolarHBondContact O-CG1 3.34Å; L227-I231 PolarHBondContact O-N 3.04Å; G228-I231 PolarHBondContact O-N 3.22Å; I231-V233 VanDerWaalsContact C-N 3.28Å; I231-V233 PolarHBondContact O-N 2.61Å; I231-M234 HydrophobicContact CG1-CE 4.19Å; I231-M234 PolarHBondContact O-N 2.85Å; I231-L235 HydrophobicContact CG2-CD1 3.69Å; I231-L235 HydrophobicContact CG2-CG 4.24Å; I231-L235 WeakPolarHBondContact O-CB 3.27Å; I231-L235 VanDerWaalsContact O-CG 3.24Å; I231-L235 WeakPolarHBondContact O-CG 3.04Å; I231-L235 PolarHBondContact O-N 3.38Å; I231-V280 HydrophobicContact CG2-CG1 4.49Å; I231-V281 HydrophobicContact CB-CG2 4.11Å; I231-V281 HydrophobicContact CG2-CG2 3.5Å; I231-L284 HydrophobicContact CD1-CD1 3.55Å; I231-W303 HydrophobicContact CD1-CZ3 4.39Å; I231-W303 HydrophobicContact CG1-CZ3 4.43Å; I231-W303 HydrophobicContact CG2-CH2 3.88Å; I231-W303 HydrophobicContact CG2-CZ3 3.94Å
232Y93.3Very high87.9Confident5 Ų510 Ų102%0.024%0.044CC..Hα-helixtrans-53.4-48.7178.3-175.2-74.3000111G228 V229 L235 C236 Y238 P240 F263 E264 F265 W270 V281G228-Y232 WeakPolarHBondContact O-CB 3.17Å; G228-Y232 PolarHBondContact O-N 3.19Å; V229-Y232 PolarHBondContact O-N 3.09Å; Y232-L235 PolarHBondContact O-N 2.92Å; Y232-C236 VanDerWaalsContact CD1-SG 3.59Å; Y232-C236 WeakPolarHBondContact CE1-SG 3.46Å; Y232-C236 PolarHBondContact O-N 3.18Å; Y232-C236 PolarHBondContact O-SG 2.62Å; Y232-C236 VanDerWaalsContact O-SG 3.33Å; Y232-Y238 WeakPolarHBondContact CD1-O 3.09Å; Y232-Y238 AromaticContact CE1-CD2 3.86Å; Y232-Y238 HydrophobicContact CE1-CD2 3.86Å; Y232-Y238 AromaticContact CE1-CE2 3.78Å; Y232-Y238 HydrophobicContact CE1-CE2 3.78Å; Y232-Y238 VanDerWaalsContact CE1-O 3.25Å; Y232-Y238 WeakPolarHBondContact CE1-O 3.39Å; Y232-Y238 AromaticContact CZ-CE2 3.96Å; Y232-Y238 WeakPolarHBondContact OH-CE2 3.38Å; Y232-P240 HydrophobicContact CD1-CB 3.86Å; Y232-P240 HydrophobicContact CD1-CG 4.12Å; Y232-P240 HydrophobicContact CD2-CB 3.73Å; Y232-P240 HydrophobicContact CD2-CG 4.41Å; Y232-P240 HydrophobicContact CE1-CB 3.99Å; Y232-P240 HydrophobicContact CE2-CB 3.89Å; Y232-P240 HydrophobicContact CG-CB 3.76Å; Y232-P240 HydrophobicContact CG-CG 4.01Å; Y232-F263 HydrophobicContact CD2-CD2 4.18Å; Y232-F263 HydrophobicContact CD2-CE2 4.39Å; Y232-F263 AromaticContact CE2-CD2 3.85Å; Y232-F263 HydrophobicContact CE2-CD2 3.85Å; Y232-F263 HydrophobicContact CE2-CE2 4.38Å; Y232-E264 PolarHBondContact OH-O 2.63Å; Y232-F265 HydrophobicContact CD2-CE1 4.08Å; Y232-F265 AromaticContact CE2-CD1 3.92Å; Y232-F265 HydrophobicContact CE2-CD1 3.92Å; Y232-F265 AromaticContact CE2-CE1 3.91Å; Y232-F265 HydrophobicContact CE2-CE1 3.91Å; Y232-W270 HydrophobicContact CD1-CZ2 4.04Å; Y232-W270 AromaticContact CD2-CH2 3.84Å; Y232-W270 HydrophobicContact CD2-CH2 3.84Å; Y232-W270 AromaticContact CD2-CZ2 3.56Å; Y232-W270 HydrophobicContact CD2-CZ2 3.56Å; Y232-W270 AromaticContact CE1-CZ2 3.9Å; Y232-W270 HydrophobicContact CE1-CZ2 3.9Å; Y232-W270 HydrophobicContact CE2-CH2 4.04Å; Y232-W270 AromaticContact CE2-CZ2 3.38Å; Y232-W270 HydrophobicContact CE2-CZ2 3.38Å; Y232-W270 HydrophobicContact CG-CH2 4.19Å; Y232-W270 AromaticContact CG-CZ2 3.85Å; Y232-W270 HydrophobicContact CG-CZ2 3.85Å; Y232-W270 AromaticContact CZ-CE2 3.97Å; Y232-W270 AromaticContact CZ-CZ2 3.54Å; Y232-W270 AromaticContact CZ-NE1 3.92Å; Y232-V281 HydrophobicContact CD2-CG1 3.87Å
233V91.3Very high86.5Confident2 Ų210.2 Ų10.21%0.0125%0.046CC..Hα-helixtrans-66.9-41.41801740000112F111 V229 I230 I231 L235 G237 Y238 P239 M320 I329F111-V233 HydrophobicContact CD1-CG1 4.4Å; F111-V233 HydrophobicContact CD2-CG1 4.11Å; F111-V233 HydrophobicContact CE1-CB 4.28Å; F111-V233 HydrophobicContact CE1-CG1 3.75Å; F111-V233 HydrophobicContact CE2-CB 4.12Å; F111-V233 HydrophobicContact CE2-CG1 3.37Å; F111-V233 HydrophobicContact CZ-CB 3.61Å; F111-V233 HydrophobicContact CZ-CG1 3.2Å; F111-V233 HydrophobicContact CZ-CG2 4.48Å; V229-V233 HydrophobicContact CG1-CG2 4.45Å; V229-V233 VanDerWaalsContact O-CG2 3.25Å; V229-V233 WeakPolarHBondContact O-CG2 3.24Å; V229-V233 PolarHBondContact O-N 3.13Å; I230-V233 PolarHBondContact O-N 3.27Å; I231-V233 VanDerWaalsContact C-N 3.28Å; I231-V233 PolarHBondContact O-N 2.61Å; V233-L235 PolarHBondContact O-N 3.19Å; V233-G237 VanDerWaalsContact O-CA 3.29Å; V233-G237 WeakPolarHBondContact O-CA 3.33Å; V233-G237 PolarHBondContact O-N 3.35Å; V233-Y238 WeakPolarHBondContact CG2-O 3.17Å; V233-P239 HydrophobicContact CG2-CB 4.32Å; V233-M320 HydrophobicContact CG1-CE 3.23Å; V233-M320 WeakPolarHBondContact O-CE 3.08Å; V233-I329 HydrophobicContact CG1-CD1 4.47Å; V233-I329 HydrophobicContact CG1-CG2 3.81Å; V233-I329 HydrophobicContact CG2-CG2 4.11Å
234M93.6Very high84.7Confident0 Ų019.3 Ų19.30%09%0.085CC..Hα-helixtrans-59.8-34.1175.8-77.8-167.4-60.600112.1L110 F111 I114 F120 A125 V128 T129 I230 I231 S316L110-M234 HydrophobicContact CD1-SD 4.11Å; L110-M234 HydrophobicContact CD2-CG 4.33Å; L110-M234 HydrophobicContact CD2-SD 3.88Å; L110-M234 HydrophobicContact CG-SD 4.4Å; F111-M234 HydrophobicContact CE1-CG 3.75Å; I114-M234 HydrophobicContact CD1-CG 3.92Å; I114-M234 HydrophobicContact CD1-SD 4.42Å; F120-M234 HydrophobicContact CE1-CB 4.26Å; A125-M234 HydrophobicContact CB-CB 4.49Å; V128-M234 HydrophobicContact CB-SD 4.32Å; V128-M234 HydrophobicContact CG1-CE 4.45Å; V128-M234 HydrophobicContact CG1-SD 3.76Å; T129-M234 WeakPolarHBondContact OG1-CE 3.44Å; I230-M234 HydrophobicContact CG2-CE 4.04Å; I230-M234 HydrophobicContact CG2-CG 4.33Å; I230-M234 HydrophobicContact CG2-SD 4.35Å; I230-M234 WeakPolarHBondContact O-CB 3.07Å; I230-M234 WeakPolarHBondContact O-CG 3.45Å; I230-M234 PolarHBondContact O-N 3.21Å; I231-M234 HydrophobicContact CG1-CE 4.19Å; I231-M234 PolarHBondContact O-N 2.85Å; M234-S316 WeakPolarHBondContact O-CB 3.47Å; M234-S316 PolarHBondContact O-OG 3.46Å
235L93.4Very high82.6Confident0 Ų025.8 Ų25.80%012%0.115CC..Hα-helixtrans-76.1-48.5-178.4-72.6174.4000112E122 A125 I231 Y232 V233 W270 I273 A277 V281 W303 L314 P315E122-L235 HydrophobicContact CG-CD2 4.11Å; A125-L235 HydrophobicContact CB-CD2 4.32Å; I231-L235 HydrophobicContact CG2-CD1 3.69Å; I231-L235 HydrophobicContact CG2-CG 4.24Å; I231-L235 WeakPolarHBondContact O-CB 3.27Å; I231-L235 VanDerWaalsContact O-CG 3.24Å; I231-L235 WeakPolarHBondContact O-CG 3.04Å; I231-L235 PolarHBondContact O-N 3.38Å; Y232-L235 PolarHBondContact O-N 2.92Å; V233-L235 PolarHBondContact O-N 3.19Å; L235-W270 HydrophobicContact CB-CH2 3.84Å; L235-W270 HydrophobicContact CB-CZ2 4.42Å; L235-W270 HydrophobicContact CB-CZ3 4.18Å; L235-W270 HydrophobicContact CD1-CH2 3.85Å; L235-W270 HydrophobicContact CD1-CZ3 3.84Å; L235-I273 HydrophobicContact CB-CD1 4.08Å; L235-I273 HydrophobicContact CD1-CG2 4.35Å; L235-I273 HydrophobicContact CD2-CG2 4.16Å; L235-A277 HydrophobicContact CD1-CB 3.82Å; L235-A277 HydrophobicContact CD2-CB 4.28Å; L235-V281 HydrophobicContact CD1-CG2 4.2Å; L235-W303 HydrophobicContact CD2-CZ2 4.08Å; L235-L314 HydrophobicContact CD2-CD1 4.07Å; L235-L314 HydrophobicContact CD2-CD2 3.86Å; L235-P315 WeakPolarHBondContact O-CD 3.48Å
236C89.6Confident80.4Confident0 Ų033.5 Ų33.50%015%0.151CC..Hα-helixtrans-116-10.7-17177.20000116Y232 Y238 E269 W270 L319Y232-C236 VanDerWaalsContact CD1-SG 3.59Å; Y232-C236 WeakPolarHBondContact CE1-SG 3.46Å; Y232-C236 PolarHBondContact O-N 3.18Å; Y232-C236 PolarHBondContact O-SG 2.62Å; Y232-C236 VanDerWaalsContact O-SG 3.33Å; C236-Y238 HydrophobicContact CB-CD1 4.19Å; C236-Y238 HydrophobicContact CB-CE1 3.73Å; C236-Y238 WeakPolarHBondContact O-CD1 3.43Å; C236-Y238 VanDerWaalsContact SG-CD1 3.54Å; C236-Y238 WeakPolarHBondContact SG-CE1 3.36Å; C236-Y238 VanDerWaalsContact SG-CZ 3.55Å; C236-Y238 PolarHBondContact SG-O 3.44Å; C236-E269 HydrophobicContact CB-CB 4.22Å; C236-W270 HydrophobicContact CB-CD2 4.39Å; C236-W270 VanDerWaalsContact CB-CE2 3.47Å; C236-W270 HydrophobicContact CB-CZ2 3.61Å; C236-W270 VanDerWaalsContact CB-NE1 3.28Å; C236-L319 WeakPolarHBondContact O-CD1 3.37Å
237G87.5Confident78.2Confident2 Ų236.5 Ų36.52%0.02117%0.172CC..SBendtrans89.12.4175.800000116.3V233 I329V233-G237 VanDerWaalsContact O-CA 3.29Å; V233-G237 WeakPolarHBondContact O-CA 3.33Å; V233-G237 PolarHBondContact O-N 3.35Å; G237-I329 WeakPolarHBondContact O-CD1 3.34Å
238Y83.3Confident75.7Confident52 Ų5248 Ų4820%0.20422%0.216CC..SBendtrans-142.3159.6179.857-93.8000111.5Y232 V233 C236 P266 E269 W270 L319Y232-Y238 WeakPolarHBondContact CD1-O 3.09Å; Y232-Y238 AromaticContact CE1-CD2 3.86Å; Y232-Y238 HydrophobicContact CE1-CD2 3.86Å; Y232-Y238 AromaticContact CE1-CE2 3.78Å; Y232-Y238 HydrophobicContact CE1-CE2 3.78Å; Y232-Y238 VanDerWaalsContact CE1-O 3.25Å; Y232-Y238 WeakPolarHBondContact CE1-O 3.39Å; Y232-Y238 AromaticContact CZ-CE2 3.96Å; Y232-Y238 WeakPolarHBondContact OH-CE2 3.38Å; V233-Y238 WeakPolarHBondContact CG2-O 3.17Å; C236-Y238 HydrophobicContact CB-CD1 4.19Å; C236-Y238 HydrophobicContact CB-CE1 3.73Å; C236-Y238 WeakPolarHBondContact O-CD1 3.43Å; C236-Y238 VanDerWaalsContact SG-CD1 3.54Å; C236-Y238 WeakPolarHBondContact SG-CE1 3.36Å; C236-Y238 VanDerWaalsContact SG-CZ 3.55Å; C236-Y238 PolarHBondContact SG-O 3.44Å; Y238-P266 VanDerWaalsContact OH-CD 3.24Å; Y238-P266 WeakPolarHBondContact OH-CD 3.28Å; Y238-P266 VanDerWaalsContact OH-CG 3.23Å; Y238-P266 WeakPolarHBondContact OH-CG 3.32Å; Y238-E269 HydrophobicContact CE1-CB 4.18Å; Y238-E269 HydrophobicContact CE1-CG 3.84Å; Y238-E269 WeakPolarHBondContact CE1-OE2 3.44Å; Y238-E269 PolarHBondContact OH-OE2 3.18Å; Y238-W270 AromaticContact CZ-NE1 3.88Å; Y238-W270 PolarHBondContact OH-NE1 3.38Å; Y238-L319 HydrophobicContact CD1-CD1 4.41Å
239P83.6Confident73.2Confident10 Ų1052.7 Ų52.77%0.06524%0.244CC..  trans-78.3148.2-175.831.5-29.3000111.3V233 F241 Y242V233-P239 HydrophobicContact CG2-CB 4.32Å; P239-F241 PolarHBondContact O-N 3.05Å; P239-F241 VanDerWaalsContact O-N 3.17Å; P239-Y242 HydrophobicContact CG-CD2 4.2Å
240P79.6Confident71.3Confident9 Ų954.2 Ų54.26%0.05825%0.252CS..SBendtrans-64.1-23.5-178.121.2-29.4000113.5V229 Y232 F263 L285V229-P240 HydrophobicContact CG1-CG 4.33Å; V229-P240 HydrophobicContact CG2-CG 4.2Å; Y232-P240 HydrophobicContact CD1-CB 3.86Å; Y232-P240 HydrophobicContact CD1-CG 4.12Å; Y232-P240 HydrophobicContact CD2-CB 3.73Å; Y232-P240 HydrophobicContact CD2-CG 4.41Å; Y232-P240 HydrophobicContact CE1-CB 3.99Å; Y232-P240 HydrophobicContact CE2-CB 3.89Å; Y232-P240 HydrophobicContact CG-CB 3.76Å; Y232-P240 HydrophobicContact CG-CG 4.01Å; P240-F263 HydrophobicContact CB-CB 3.93Å; P240-F263 HydrophobicContact CB-CD2 4.41Å; P240-F263 HydrophobicContact CB-CG 4.2Å; P240-F263 WeakPolarHBondContact O-CB 3.36Å; P240-L285 HydrophobicContact CB-CD1 4.14Å; P240-L285 HydrophobicContact CG-CD1 4.04Å
241F74.4Confident69.7Low2 Ų255.3 Ų55.31%0.00926%0.259CS..SBendtrans-117.674.6-177.7-48-71.6000109.9W225 V229 P239 M254 K257 I258 F263 L285W225-F241 HydrophobicContact CH2-CE2 4.22Å; W225-F241 AromaticContact CH2-CZ 3.81Å; W225-F241 HydrophobicContact CH2-CZ 3.81Å; W225-F241 HydrophobicContact CZ2-CD2 4.47Å; W225-F241 AromaticContact CZ2-CE2 3.46Å; W225-F241 HydrophobicContact CZ2-CE2 3.46Å; W225-F241 VanDerWaalsContact CZ2-CE2 3.46Å; W225-F241 AromaticContact CZ2-CZ 3.53Å; W225-F241 HydrophobicContact CZ2-CZ 3.53Å; V229-F241 HydrophobicContact CG2-CE2 4.42Å; P239-F241 PolarHBondContact O-N 3.05Å; P239-F241 VanDerWaalsContact O-N 3.17Å; F241-M254 HydrophobicContact CB-CG 4.33Å; F241-M254 WeakPolarHBondContact O-CE 3.24Å; F241-M254 WeakPolarHBondContact O-CG 3.48Å; F241-K257 HydrophobicContact CD1-CB 4.06Å; F241-I258 HydrophobicContact CB-CD1 4.37Å; F241-I258 HydrophobicContact CB-CG1 3.8Å; F241-I258 HydrophobicContact CD1-CG1 4.06Å; F241-I258 HydrophobicContact CD2-CG1 3.87Å; F241-I258 HydrophobicContact CG-CG1 3.62Å; F241-F263 HydrophobicContact CD1-CB 4.33Å; F241-F263 HydrophobicContact CE1-CB 3.96Å; F241-F263 HydrophobicContact CE1-CD1 4.06Å; F241-F263 HydrophobicContact CE1-CG 4.42Å; F241-F263 HydrophobicContact CZ-CD1 4.12Å; F241-L285 HydrophobicContact CZ-CD1 4.44Å
242Y63.6Low67.8Low108 Ų10864.3 Ų64.342%0.42430%0.298SS..  trans-99.4147.1175.6-168.3-103000112.4P239 H246 K257P239-Y242 HydrophobicContact CG-CD2 4.2Å; Y242-H246 PolarHBondContact OH-CE1 3.02Å; Y242-H246 PolarHBondContact OH-NE2 3.27Å; Y242-K257 PolarHBondContact O-NZ 3.25Å; Y242-K257 VanDerWaalsContact O-NZ 3.16Å
243S54.8Low66.2Low13 Ų1367.5 Ų67.59%0.09132%0.315CS..  trans-115.9131.9170164.70000109H245 P251S243-H245 PolarHBondContact O-N 2.87Å; S243-H245 PolarHBondContact OG-N 2.93Å; S243-H245 PolarHBondContact OG-O 3.32Å; S243-P251 WeakPolarHBondContact OG-CB 3.23Å; S243-P251 WeakPolarHBondContact OG-CG 3.45Å
244K50.3Low64.8Low192 Ų19268 Ų6884%0.83532%0.318SS*.SBendtrans-60.8-16.8176.2-66.4-175.5177.2-176.70113.3
245H48.2Very low63.2Low138 Ų13875.6 Ų75.664%0.63935%0.347SS*.SBendtrans-98.9113.6176.9-61.6-65.8000111.2S243 S247 P251S243-H245 PolarHBondContact O-N 2.87Å; S243-H245 PolarHBondContact OG-N 2.93Å; S243-H245 PolarHBondContact OG-O 3.32Å; H245-S247 PolarHBondContact O-N 3.28Å; H245-P251 WeakPolarHBondContact O-CG 3.46Å
246H44.2Very low61.8Low168 Ų16882.4 Ų82.478%0.77837%0.372SS*.  trans-71.1108.5168.9-69.176000108.9Y242Y242-H246 PolarHBondContact OH-CE1 3.02Å; Y242-H246 PolarHBondContact OH-NE2 3.27Å
247S43Very low60.7Low65 Ų6586.3 Ų86.346%0.45539%0.389SS..  trans-124.2149.9172172.30000108.6H245 T249H245-S247 PolarHBondContact O-N 3.28Å; S247-T249 VanDerWaalsContact CB-O 3.25Å; S247-T249 WeakPolarHBondContact CB-O 3.49Å; S247-T249 PolarHBondContact O-N 2.91Å; S247-T249 VanDerWaalsContact O-N 3.09Å; S247-T249 PolarHBondContact OG-N 2.78Å; S247-T249 PolarHBondContact OG-O 3.48Å; S247-T249 VanDerWaalsContact OG-O 3.11Å; S247-T249 PolarHBondContact OG-OG1 3.24Å
248R41.8Very low59.6Low242 Ų24287.5 Ų87.591%0.91340%0.395SS*.SBendtrans-66.3-4.9173.3-62.2-171.9-166130.41.5113.4
249T43.9Very low58.6Low97 Ų9790.5 Ų90.560%0.59541%0.412SS*.SBendtrans-130.1142.917554.40000108.5S247 P251S247-T249 VanDerWaalsContact CB-O 3.25Å; S247-T249 WeakPolarHBondContact CB-O 3.49Å; S247-T249 PolarHBondContact O-N 2.91Å; S247-T249 VanDerWaalsContact O-N 3.09Å; S247-T249 PolarHBondContact OG-N 2.78Å; S247-T249 PolarHBondContact OG-O 3.48Å; S247-T249 VanDerWaalsContact OG-O 3.11Å; S247-T249 PolarHBondContact OG-OG1 3.24Å; T249-P251 WeakPolarHBondContact O-CD 3.34Å
250I49.8Very low57.8Low33 Ų3394.2 Ų94.217%0.16944%0.435CS..  trans-46.6115.2174.6-62.3-173.5000109.3K252 M254 R255 E335 N339I250-K252 PolarHBondContact O-N 3.32Å; I250-M254 HydrophobicContact CD1-CE 4.44Å; I250-M254 HydrophobicContact CG2-CB 3.69Å; I250-M254 HydrophobicContact CG2-CE 4.47Å; I250-M254 HydrophobicContact CG2-CG 3.74Å; I250-M254 HydrophobicContact CG2-SD 3.87Å; I250-R255 HydrophobicContact CG2-CB 4.05Å; I250-E335 HydrophobicContact CD1-CB 4.09Å; I250-E335 HydrophobicContact CG1-CB 4.21Å; I250-E335 WeakPolarHBondContact CG1-OE2 3.46Å; I250-N339 WeakPolarHBondContact CD1-ND2 3.25Å
251P58.4Low57.2Low24 Ų2494.6 Ų94.616%0.15644%0.44CS..  trans-56141.5176.2-28.238.5000109.7S243 H245 T249 D253 M254 R255S243-P251 WeakPolarHBondContact OG-CB 3.23Å; S243-P251 WeakPolarHBondContact OG-CG 3.45Å; H245-P251 WeakPolarHBondContact O-CG 3.46Å; T249-P251 WeakPolarHBondContact O-CD 3.34Å; P251-D253 PolarHBondContact O-N 2.95Å; P251-M254 PolarHBondContact O-N 2.75Å; P251-R255 PolarHBondContact O-N 3.13Å
252K56.9Low57.2Low188 Ų18897.2 Ų97.282%0.81746%0.459SS*.Hα-helixtrans-49.4-32.7-178.6-71.9-177.9178.6177.70112.3I250 R256I250-K252 PolarHBondContact O-N 3.32Å; K252-R256 WeakPolarHBondContact O-CB 3.33Å; K252-R256 PolarHBondContact O-N 2.91Å
253D59.6Low58.2Low72 Ų7293.9 Ų93.939%0.38545%0.446SS..Hα-helixtrans-66.7-41.2176.6-63.9-33.6000113.8P251 R256 K257P251-D253 PolarHBondContact O-N 2.95Å; D253-R256 WeakPolarHBondContact O-CB 3.47Å; D253-R256 PolarHBondContact O-N 2.54Å; D253-R256 IonicContact OD1-CZ 3.88Å; D253-R256 IonicContact OD1-NE 3.95Å; D253-R256 IonicContact OD1-NH2 3.72Å; D253-R256 PolarHBondContact OD1-NH2 3.26Å; D253-K257 WeakPolarHBondContact O-CG 3.07Å; D253-K257 PolarHBondContact O-N 3.1Å
254M60.9Low59.7Low13 Ų13100.1 Ų100.16%0.06447%0.474CS..Hα-helixtrans-67.8-42176.5178-179.416500110.8F241 I250 P251 R256 K257 I258 A332F241-M254 HydrophobicContact CB-CG 4.33Å; F241-M254 WeakPolarHBondContact O-CE 3.24Å; F241-M254 WeakPolarHBondContact O-CG 3.48Å; I250-M254 HydrophobicContact CD1-CE 4.44Å; I250-M254 HydrophobicContact CG2-CB 3.69Å; I250-M254 HydrophobicContact CG2-CE 4.47Å; I250-M254 HydrophobicContact CG2-CG 3.74Å; I250-M254 HydrophobicContact CG2-SD 3.87Å; P251-M254 PolarHBondContact O-N 2.75Å; M254-R256 VanDerWaalsContact C-N 3.31Å; M254-R256 PolarHBondContact O-N 3.31Å; M254-K257 PolarHBondContact O-N 3.42Å; M254-I258 HydrophobicContact CE-CD1 4.18Å; M254-I258 HydrophobicContact CG-CD1 4.14Å; M254-I258 WeakPolarHBondContact O-CG1 3.19Å; M254-I258 PolarHBondContact O-N 3.29Å; M254-A332 HydrophobicContact CE-CB 4.41Å
255R60.1Low61.7Low160 Ų16093.4 Ų93.460%0.60445%0.445SS*.Hα-helixtrans-60.3-42.8173.3-173.9179.4175.5178.51111.3I250 P251 I258 M259I250-R255 HydrophobicContact CG2-CB 4.05Å; P251-R255 PolarHBondContact O-N 3.13Å; R255-I258 PolarHBondContact O-N 3.46Å; R255-M259 HydrophobicContact CG-CE 4.05Å; R255-M259 HydrophobicContact CG-CG 4.48Å; R255-M259 HydrophobicContact CG-SD 4.16Å; R255-M259 WeakPolarHBondContact O-CB 3.49Å; R255-M259 VanDerWaalsContact O-CG 3.27Å; R255-M259 WeakPolarHBondContact O-CG 3.24Å; R255-M259 PolarHBondContact O-N 2.88Å
256R63.7Low63.6Low143 Ų14389.2 Ų89.254%0.5443%0.43SS..Hα-helixtrans-59.8-49.5175175.5170.354.7166.3-2.2111.3K252 D253 M254 I258 M259 T260K252-R256 WeakPolarHBondContact O-CB 3.33Å; K252-R256 PolarHBondContact O-N 2.91Å; D253-R256 WeakPolarHBondContact O-CB 3.47Å; D253-R256 PolarHBondContact O-N 2.54Å; D253-R256 IonicContact OD1-CZ 3.88Å; D253-R256 IonicContact OD1-NE 3.95Å; D253-R256 IonicContact OD1-NH2 3.72Å; D253-R256 PolarHBondContact OD1-NH2 3.26Å; M254-R256 VanDerWaalsContact C-N 3.31Å; M254-R256 PolarHBondContact O-N 3.31Å; R256-I258 VanDerWaalsContact C-N 3.31Å; R256-I258 PolarHBondContact O-N 3.45Å; R256-M259 PolarHBondContact O-N 3.32Å; R256-M259 VanDerWaalsContact O-N 3.14Å; R256-T260 HydrophobicContact CG-CG2 4.34Å; R256-T260 WeakPolarHBondContact O-CG2 3.34Å; R256-T260 PolarHBondContact O-N 2.95Å; R256-T260 PolarHBondContact O-OG1 3.46Å
257K66.4Low65.7Low82 Ų8289.1 Ų89.136%0.35743%0.43SS..Hα-helixtrans-57.3-41.4177.4-74.7-178.8178.9-1730112.8F241 Y242 D253 M254 T260 G261 S262F241-K257 HydrophobicContact CD1-CB 4.06Å; Y242-K257 PolarHBondContact O-NZ 3.25Å; Y242-K257 VanDerWaalsContact O-NZ 3.16Å; D253-K257 WeakPolarHBondContact O-CG 3.07Å; D253-K257 PolarHBondContact O-N 3.1Å; M254-K257 PolarHBondContact O-N 3.42Å; K257-T260 PolarHBondContact O-N 2.88Å; K257-T260 PolarHBondContact O-OG1 3.29Å; K257-G261 CarbonylContact O-C 3.55Å; K257-G261 WeakPolarHBondContact O-CA 3.3Å; K257-G261 PolarHBondContact O-N 3.46Å; K257-S262 PolarHBondContact O-N 2.84Å
258I65.8Low67.8Low27 Ų2794.1 Ų94.114%0.13845%0.446CS..Hα-helixtrans-64.1-47.9175.2-66.9164000110.6W225 F241 M254 R255 R256 T260 G261 Q336W225-I258 HydrophobicContact CZ2-CG2 4.16Å; F241-I258 HydrophobicContact CB-CD1 4.37Å; F241-I258 HydrophobicContact CB-CG1 3.8Å; F241-I258 HydrophobicContact CD1-CG1 4.06Å; F241-I258 HydrophobicContact CD2-CG1 3.87Å; F241-I258 HydrophobicContact CG-CG1 3.62Å; M254-I258 HydrophobicContact CE-CD1 4.18Å; M254-I258 HydrophobicContact CG-CD1 4.14Å; M254-I258 WeakPolarHBondContact O-CG1 3.19Å; M254-I258 PolarHBondContact O-N 3.29Å; R255-I258 PolarHBondContact O-N 3.46Å; R256-I258 VanDerWaalsContact C-N 3.31Å; R256-I258 PolarHBondContact O-N 3.45Å; I258-T260 VanDerWaalsContact C-N 3.29Å; I258-T260 PolarHBondContact O-N 2.99Å; I258-G261 PolarHBondContact O-N 3.11Å; I258-Q336 HydrophobicContact CD1-CG 4.06Å
259M62.7Low69.9Low115 Ų11584.3 Ų84.357%0.56741%0.411SS*.Hα-helixtrans-66.8-29.2-179.4-69.7-175.2-49.600113.1R255 R256 V287R255-M259 HydrophobicContact CG-CE 4.05Å; R255-M259 HydrophobicContact CG-CG 4.48Å; R255-M259 HydrophobicContact CG-SD 4.16Å; R255-M259 WeakPolarHBondContact O-CB 3.49Å; R255-M259 VanDerWaalsContact O-CG 3.27Å; R255-M259 WeakPolarHBondContact O-CG 3.24Å; R255-M259 PolarHBondContact O-N 2.88Å; R256-M259 PolarHBondContact O-N 3.32Å; R256-M259 VanDerWaalsContact O-N 3.14Å; M259-V287 WeakPolarHBondContact O-CG1 3.25Å
260T66.2Low72.3Confident87 Ų8779.8 Ų79.853%0.53438%0.383SS..Hα-helixtrans-93.3-6.7176.360.40000113.2R256 K257 I258 S262 V287R256-T260 HydrophobicContact CG-CG2 4.34Å; R256-T260 WeakPolarHBondContact O-CG2 3.34Å; R256-T260 PolarHBondContact O-N 2.95Å; R256-T260 PolarHBondContact O-OG1 3.46Å; K257-T260 PolarHBondContact O-N 2.88Å; K257-T260 PolarHBondContact O-OG1 3.29Å; I258-T260 VanDerWaalsContact C-N 3.29Å; I258-T260 PolarHBondContact O-N 2.99Å; T260-S262 PolarHBondContact O-N 3.18Å; T260-S262 VanDerWaalsContact OG1-CB 3.31Å; T260-S262 WeakPolarHBondContact OG1-CB 3.25Å; T260-V287 VanDerWaalsContact C-CG2 3.41Å
261G65.9Low74.2Confident17 Ų1781.7 Ų81.718%0.17540%0.399CS..THydrogen-bonded Turntrans59.926.6-173.800000112.8K257 I258 F263K257-G261 CarbonylContact O-C 3.55Å; K257-G261 WeakPolarHBondContact O-CA 3.3Å; K257-G261 PolarHBondContact O-N 3.46Å; I258-G261 PolarHBondContact O-N 3.11Å; G261-F263 WeakPolarHBondContact O-CD1 3.36Å; G261-F263 PolarHBondContact O-N 3.2Å
262S75.9Confident75.6Confident57 Ų5786.8 Ų86.840%0.39942%0.421SS..  trans-86.6100.5-177.3178.70000109.2K257 T260K257-S262 PolarHBondContact O-N 2.84Å; T260-S262 PolarHBondContact O-N 3.18Å; T260-S262 VanDerWaalsContact OG1-CB 3.31Å; T260-S262 WeakPolarHBondContact OG1-CB 3.25Å
263F83.8Confident77.3Confident38 Ų3878.2 Ų78.217%0.16738%0.384CS..  trans-134.1160.8168.567.9-84000108.5Y232 P240 F241 G261 F265 V281 R282 L285Y232-F263 HydrophobicContact CD2-CD2 4.18Å; Y232-F263 HydrophobicContact CD2-CE2 4.39Å; Y232-F263 AromaticContact CE2-CD2 3.85Å; Y232-F263 HydrophobicContact CE2-CD2 3.85Å; Y232-F263 HydrophobicContact CE2-CE2 4.38Å; P240-F263 HydrophobicContact CB-CB 3.93Å; P240-F263 HydrophobicContact CB-CD2 4.41Å; P240-F263 HydrophobicContact CB-CG 4.2Å; P240-F263 WeakPolarHBondContact O-CB 3.36Å; F241-F263 HydrophobicContact CD1-CB 4.33Å; F241-F263 HydrophobicContact CE1-CB 3.96Å; F241-F263 HydrophobicContact CE1-CD1 4.06Å; F241-F263 HydrophobicContact CE1-CG 4.42Å; F241-F263 HydrophobicContact CZ-CD1 4.12Å; G261-F263 WeakPolarHBondContact O-CD1 3.36Å; G261-F263 PolarHBondContact O-N 3.2Å; F263-F265 HydrophobicContact CD2-CE1 4.4Å; F263-F265 HydrophobicContact CD2-CZ 4.42Å; F263-F265 AromaticContact CE2-CE1 3.86Å; F263-F265 HydrophobicContact CE2-CE1 3.86Å; F263-F265 HydrophobicContact CE2-CE2 4.15Å; F263-F265 AromaticContact CE2-CZ 3.57Å; F263-F265 HydrophobicContact CE2-CZ 3.57Å; F263-F265 HydrophobicContact CZ-CZ 4.41Å; F263-V281 HydrophobicContact CE2-CG1 3.93Å; F263-V281 HydrophobicContact CZ-CG1 4.18Å; F263-R282 HydrophobicContact CZ-CG 4.31Å; F263-L285 HydrophobicContact CD1-CB 4.28Å; F263-L285 HydrophobicContact CD1-CD1 4.17Å; F263-L285 HydrophobicContact CD2-CD1 4.48Å; F263-L285 HydrophobicContact CE1-CB 3.47Å; F263-L285 VanDerWaalsContact CE1-CB 3.47Å; F263-L285 HydrophobicContact CE1-CD1 3.87Å; F263-L285 HydrophobicContact CE1-CG 4.31Å; F263-L285 HydrophobicContact CE2-CD1 4.17Å; F263-L285 HydrophobicContact CG-CD1 4.47Å; F263-L285 HydrophobicContact CZ-CB 3.83Å; F263-L285 HydrophobicContact CZ-CD1 3.85Å; F263-L285 HydrophobicContact CZ-CG 4.4Å
264E87.3Confident78.9Confident145 Ų14575.9 Ų75.968%0.67837%0.373SS*.  trans-128.2169.4-175-68.1172.9-174.400109.5Y232 P266Y232-E264 PolarHBondContact OH-O 2.63Å; E264-P266 WeakPolarHBondContact O-CD 3.45Å
265F91.3Very high80.5Confident50 Ų5080.5 Ų80.522%0.21940%0.395CS..  trans-117.783.5171.9-59.7-66000108.8Y232 F263 E267 W270 K278 V281 R282Y232-F265 HydrophobicContact CD2-CE1 4.08Å; Y232-F265 AromaticContact CE2-CD1 3.92Å; Y232-F265 HydrophobicContact CE2-CD1 3.92Å; Y232-F265 AromaticContact CE2-CE1 3.91Å; Y232-F265 HydrophobicContact CE2-CE1 3.91Å; F263-F265 HydrophobicContact CD2-CE1 4.4Å; F263-F265 HydrophobicContact CD2-CZ 4.42Å; F263-F265 AromaticContact CE2-CE1 3.86Å; F263-F265 HydrophobicContact CE2-CE1 3.86Å; F263-F265 HydrophobicContact CE2-CE2 4.15Å; F263-F265 AromaticContact CE2-CZ 3.57Å; F263-F265 HydrophobicContact CE2-CZ 3.57Å; F263-F265 HydrophobicContact CZ-CZ 4.41Å; F265-E267 PolarHBondContact O-N 3.29Å; F265-W270 HydrophobicContact CB-CB 3.93Å; F265-W270 HydrophobicContact CB-CD2 3.95Å; F265-W270 HydrophobicContact CB-CE3 4.34Å; F265-W270 HydrophobicContact CB-CG 3.76Å; F265-W270 AromaticContact CD1-CD2 3.51Å; F265-W270 HydrophobicContact CD1-CD2 3.51Å; F265-W270 AromaticContact CD1-CE2 3.64Å; F265-W270 AromaticContact CD1-CE3 3.46Å; F265-W270 HydrophobicContact CD1-CE3 3.46Å; F265-W270 VanDerWaalsContact CD1-CE3 3.46Å; F265-W270 HydrophobicContact CD1-CG 4.23Å; F265-W270 AromaticContact CD1-CH2 3.71Å; F265-W270 HydrophobicContact CD1-CH2 3.71Å; F265-W270 AromaticContact CD1-CZ2 3.76Å; F265-W270 HydrophobicContact CD1-CZ2 3.76Å; F265-W270 AromaticContact CD1-CZ3 3.55Å; F265-W270 HydrophobicContact CD1-CZ3 3.55Å; F265-W270 HydrophobicContact CE1-CD2 4.41Å; F265-W270 HydrophobicContact CE1-CE3 4.02Å; F265-W270 AromaticContact CE1-CH2 3.67Å; F265-W270 HydrophobicContact CE1-CH2 3.67Å; F265-W270 HydrophobicContact CE1-CZ2 4.09Å; F265-W270 AromaticContact CE1-CZ3 3.62Å; F265-W270 HydrophobicContact CE1-CZ3 3.62Å; F265-W270 HydrophobicContact CG-CD2 4.15Å; F265-W270 HydrophobicContact CG-CE3 4.18Å; F265-W270 HydrophobicContact CG-CG 4.48Å; F265-K278 HydrophobicContact CD1-CG 4.24Å; F265-K278 HydrophobicContact CD2-CB 4.43Å; F265-K278 HydrophobicContact CD2-CD 4.42Å; F265-K278 HydrophobicContact CD2-CG 4.3Å; F265-K278 HydrophobicContact CE1-CB 4.37Å; F265-K278 HydrophobicContact CE1-CG 4.21Å; F265-K278 HydrophobicContact CE2-CB 3.98Å; F265-K278 HydrophobicContact CE2-CG 4.29Å; F265-K278 HydrophobicContact CG-CD 4.44Å; F265-K278 HydrophobicContact CG-CG 4.25Å; F265-K278 HydrophobicContact CZ-CB 3.92Å; F265-K278 HydrophobicContact CZ-CG 4.21Å; F265-V281 HydrophobicContact CE1-CB 4.48Å; F265-V281 HydrophobicContact CE1-CG1 4.09Å; F265-V281 HydrophobicContact CZ-CB 4.39Å; F265-V281 HydrophobicContact CZ-CG1 4.17Å; F265-R282 HydrophobicContact CE2-CG 3.69Å; F265-R282 HydrophobicContact CZ-CG 3.85Å
266P88.1Confident82.1Confident50 Ų5075.8 Ų75.833%0.32538%0.38SS..  trans-53.8130.6-178.5-2835.4000112.5Y238 E264 E268 E269 W270Y238-P266 VanDerWaalsContact OH-CD 3.24Å; Y238-P266 WeakPolarHBondContact OH-CD 3.28Å; Y238-P266 VanDerWaalsContact OH-CG 3.23Å; Y238-P266 WeakPolarHBondContact OH-CG 3.32Å; E264-P266 WeakPolarHBondContact O-CD 3.45Å; P266-E268 PolarHBondContact O-N 3.43Å; P266-E268 VanDerWaalsContact O-N 3.16Å; P266-E269 PolarHBondContact O-N 3.43Å; P266-W270 VanDerWaalsContact O-CB 3.25Å; P266-W270 WeakPolarHBondContact O-CB 3.49Å; P266-W270 PolarHBondContact O-N 3.32Å
267E88.3Confident83.6Confident166 Ų16669 Ų6978%0.77636%0.355SS*.Hα-helixtrans-59.7-29.7-174.3-70.2-173162.900113.4F265 E269 S271F265-E267 PolarHBondContact O-N 3.29Å; E267-E269 PolarHBondContact O-N 2.75Å; E267-S271 WeakPolarHBondContact O-CB 3.46Å; E267-S271 PolarHBondContact O-N 3.37Å; E267-S271 VanDerWaalsContact O-N 3.08Å; E267-S271 PolarHBondContact O-OG 2.97Å; E267-S271 VanDerWaalsContact O-OG 3.06Å
268E87.1Confident85Confident171 Ų17166.5 Ų66.580%0.79934%0.344SS*.Hα-helixtrans-53.7-49.6179.4-175.3171.3-176.200112P266P266-E268 PolarHBondContact O-N 3.43Å; P266-E268 VanDerWaalsContact O-N 3.16Å
269E87.1Confident86.4Confident36 Ų3666.9 Ų66.917%0.16835%0.346CS..Hα-helixtrans-99-26179.1-56.987.4-173.600113.7C236 Y238 P266 E267 I273 P315 L319C236-E269 HydrophobicContact CB-CB 4.22Å; Y238-E269 HydrophobicContact CE1-CB 4.18Å; Y238-E269 HydrophobicContact CE1-CG 3.84Å; Y238-E269 WeakPolarHBondContact CE1-OE2 3.44Å; Y238-E269 PolarHBondContact OH-OE2 3.18Å; P266-E269 PolarHBondContact O-N 3.43Å; E267-E269 PolarHBondContact O-N 2.75Å; E269-I273 WeakPolarHBondContact O-CD1 3.48Å; E269-P315 HydrophobicContact CB-CB 4.4Å; E269-P315 HydrophobicContact CB-CG 3.78Å; E269-P315 HydrophobicContact CG-CB 4.47Å; E269-P315 HydrophobicContact CG-CG 4.34Å; E269-L319 HydrophobicContact CG-CD1 4.06Å
270W92.3Very high88Confident1 Ų161.4 Ų61.40%0.00432%0.319CS..Hα-helixtrans-98.9-3.1-170.2-69.683.3000114.9Y232 L235 C236 Y238 F265 P266 Q272 I273 K278Y232-W270 HydrophobicContact CD1-CZ2 4.04Å; Y232-W270 AromaticContact CD2-CH2 3.84Å; Y232-W270 HydrophobicContact CD2-CH2 3.84Å; Y232-W270 AromaticContact CD2-CZ2 3.56Å; Y232-W270 HydrophobicContact CD2-CZ2 3.56Å; Y232-W270 AromaticContact CE1-CZ2 3.9Å; Y232-W270 HydrophobicContact CE1-CZ2 3.9Å; Y232-W270 HydrophobicContact CE2-CH2 4.04Å; Y232-W270 AromaticContact CE2-CZ2 3.38Å; Y232-W270 HydrophobicContact CE2-CZ2 3.38Å; Y232-W270 HydrophobicContact CG-CH2 4.19Å; Y232-W270 AromaticContact CG-CZ2 3.85Å; Y232-W270 HydrophobicContact CG-CZ2 3.85Å; Y232-W270 AromaticContact CZ-CE2 3.97Å; Y232-W270 AromaticContact CZ-CZ2 3.54Å; Y232-W270 AromaticContact CZ-NE1 3.92Å; L235-W270 HydrophobicContact CB-CH2 3.84Å; L235-W270 HydrophobicContact CB-CZ2 4.42Å; L235-W270 HydrophobicContact CB-CZ3 4.18Å; L235-W270 HydrophobicContact CD1-CH2 3.85Å; L235-W270 HydrophobicContact CD1-CZ3 3.84Å; C236-W270 HydrophobicContact CB-CD2 4.39Å; C236-W270 VanDerWaalsContact CB-CE2 3.47Å; C236-W270 HydrophobicContact CB-CZ2 3.61Å; C236-W270 VanDerWaalsContact CB-NE1 3.28Å; Y238-W270 AromaticContact CZ-NE1 3.88Å; Y238-W270 PolarHBondContact OH-NE1 3.38Å; F265-W270 HydrophobicContact CB-CB 3.93Å; F265-W270 HydrophobicContact CB-CD2 3.95Å; F265-W270 HydrophobicContact CB-CE3 4.34Å; F265-W270 HydrophobicContact CB-CG 3.76Å; F265-W270 AromaticContact CD1-CD2 3.51Å; F265-W270 HydrophobicContact CD1-CD2 3.51Å; F265-W270 AromaticContact CD1-CE2 3.64Å; F265-W270 AromaticContact CD1-CE3 3.46Å; F265-W270 HydrophobicContact CD1-CE3 3.46Å; F265-W270 VanDerWaalsContact CD1-CE3 3.46Å; F265-W270 HydrophobicContact CD1-CG 4.23Å; F265-W270 AromaticContact CD1-CH2 3.71Å; F265-W270 HydrophobicContact CD1-CH2 3.71Å; F265-W270 AromaticContact CD1-CZ2 3.76Å; F265-W270 HydrophobicContact CD1-CZ2 3.76Å; F265-W270 AromaticContact CD1-CZ3 3.55Å; F265-W270 HydrophobicContact CD1-CZ3 3.55Å; F265-W270 HydrophobicContact CE1-CD2 4.41Å; F265-W270 HydrophobicContact CE1-CE3 4.02Å; F265-W270 AromaticContact CE1-CH2 3.67Å; F265-W270 HydrophobicContact CE1-CH2 3.67Å; F265-W270 HydrophobicContact CE1-CZ2 4.09Å; F265-W270 AromaticContact CE1-CZ3 3.62Å; F265-W270 HydrophobicContact CE1-CZ3 3.62Å; F265-W270 HydrophobicContact CG-CD2 4.15Å; F265-W270 HydrophobicContact CG-CE3 4.18Å; F265-W270 HydrophobicContact CG-CG 4.48Å; P266-W270 VanDerWaalsContact O-CB 3.25Å; P266-W270 WeakPolarHBondContact O-CB 3.49Å; P266-W270 PolarHBondContact O-N 3.32Å; W270-Q272 VanDerWaalsContact C-N 3.29Å; W270-Q272 PolarHBondContact O-N 3.39Å; W270-I273 HydrophobicContact CD2-CD1 3.91Å; W270-I273 HydrophobicContact CE3-CB 3.99Å; W270-I273 HydrophobicContact CE3-CD1 3.75Å; W270-I273 HydrophobicContact CE3-CG1 4.44Å; W270-I273 HydrophobicContact CE3-CG2 3.82Å; W270-I273 HydrophobicContact CG-CD1 4.32Å; W270-I273 HydrophobicContact CZ3-CD1 4.22Å; W270-I273 HydrophobicContact CZ3-CG2 3.91Å; W270-I273 PolarHBondContact O-N 3.31Å; W270-K278 HydrophobicContact CE3-CD 4.42Å; W270-K278 HydrophobicContact CE3-CG 3.77Å; W270-K278 HydrophobicContact CZ3-CG 3.94Å; W270-K278 VanDerWaalsContact O-CE 3.23Å; W270-K278 WeakPolarHBondContact O-CE 3.49Å; W270-K278 PolarHBondContact O-NZ 3.34Å
271S89.8Confident89.4Confident73 Ų7357.3 Ų57.351%0.5129%0.294SS..THydrogen-bonded Turntrans-60.8-35179.655.40000113.4E267E267-S271 WeakPolarHBondContact O-CB 3.46Å; E267-S271 PolarHBondContact O-N 3.37Å; E267-S271 VanDerWaalsContact O-N 3.08Å; E267-S271 PolarHBondContact O-OG 2.97Å; E267-S271 VanDerWaalsContact O-OG 3.06Å
272Q88.9Confident90.8Very high132 Ų13260.6 Ų60.662%0.61730%0.301SS*.THydrogen-bonded Turntrans-93.6-1.9-179-57.6-56.6-65.300114W270 N312W270-Q272 VanDerWaalsContact C-N 3.29Å; W270-Q272 PolarHBondContact O-N 3.39Å; Q272-N312 PolarHBondContact O-ND2 3.33Å; Q272-N312 VanDerWaalsContact O-ND2 3.07Å
273I92.4Very high91.7Very high7 Ų761.5 Ų61.54%0.03630%0.298CS..SBendtrans-92.2131.9-177.3-58.9179000109.2L235 E269 W270 A277 K278 L314L235-I273 HydrophobicContact CB-CD1 4.08Å; L235-I273 HydrophobicContact CD1-CG2 4.35Å; L235-I273 HydrophobicContact CD2-CG2 4.16Å; E269-I273 WeakPolarHBondContact O-CD1 3.48Å; W270-I273 HydrophobicContact CD2-CD1 3.91Å; W270-I273 HydrophobicContact CE3-CB 3.99Å; W270-I273 HydrophobicContact CE3-CD1 3.75Å; W270-I273 HydrophobicContact CE3-CG1 4.44Å; W270-I273 HydrophobicContact CE3-CG2 3.82Å; W270-I273 HydrophobicContact CG-CD1 4.32Å; W270-I273 HydrophobicContact CZ3-CD1 4.22Å; W270-I273 HydrophobicContact CZ3-CG2 3.91Å; W270-I273 PolarHBondContact O-N 3.31Å; I273-A277 HydrophobicContact CG2-CB 3.79Å; I273-K278 WeakPolarHBondContact O-CE 3.41Å; I273-K278 PolarHBondContact O-NZ 3.23Å; I273-L314 HydrophobicContact CD1-CD2 4.16Å; I273-L314 HydrophobicContact CG1-CD2 3.99Å
274S93.7Very high92.1Very high23 Ų2359.7 Ų59.716%0.16129%0.29CS..  trans-60.9151.6-173810000113.2E122 M276 A277 K278E122-S274 VanDerWaalsContact OE1-CB 3.23Å; E122-S274 WeakPolarHBondContact OE1-CB 3.34Å; E122-S274 PolarHBondContact OE1-OG 3.13Å; E122-S274 PolarHBondContact OE2-N 3.43Å; S274-M276 PolarHBondContact O-N 3.02Å; S274-M276 PolarHBondContact OG-N 2.71Å; S274-A277 WeakPolarHBondContact O-CB 3.43Å; S274-A277 PolarHBondContact O-N 3.27Å; S274-A277 PolarHBondContact OG-N 3.2Å; S274-A277 VanDerWaalsContact OG-N 3.11Å; S274-K278 PolarHBondContact O-N 2.87Å; S274-K278 VanDerWaalsContact O-N 3.17Å
275E93.3Very high92.2Very high110 Ų11053 Ų5351%0.51426%0.258SS..Hα-helixtrans-64.6-27.1174.2-167.554.5-142.800111.8K278 D279 R282E275-K278 PolarHBondContact O-N 3.49Å; E275-K278 WeakPolarHBondContact OE2-CD 3.32Å; E275-D279 VanDerWaalsContact O-CB 3.27Å; E275-D279 WeakPolarHBondContact O-CB 3.47Å; E275-D279 PolarHBondContact O-N 3.36Å; E275-R282 IonicContact OE1-CZ 2.91Å; E275-R282 IonicContact OE1-NE 3.9Å; E275-R282 IonicContact OE1-NH2 3.07Å; E275-R282 PolarHBondContact OE1-NH2 3.48Å
276M94.2Very high91.9Very high62 Ų6254.9 Ų54.931%0.30527%0.267SS..Hα-helixtrans-66-39.1176-59.6169.176.800111.5S274 D279 V280 H301 P302 W303S274-M276 PolarHBondContact O-N 3.02Å; S274-M276 PolarHBondContact OG-N 2.71Å; M276-D279 PolarHBondContact O-N 3.34Å; M276-V280 PolarHBondContact O-N 2.96Å; M276-H301 PolarHBondContact O-CE1 3.07Å; M276-P302 HydrophobicContact CE-CB 3.24Å; M276-P302 WeakPolarHBondContact CE-O 3.27Å; M276-W303 HydrophobicContact CB-CB 4.04Å; M276-W303 HydrophobicContact CB-CG 4.42Å
277A94.8Very high91.4Very high0 Ų055.6 Ų55.60%027%0.27CS..Hα-helixtrans-66.9-43.3174.100000111.6E122 L235 I273 S274 D279 V280 V281 W303E122-A277 WeakPolarHBondContact OE1-CB 3.37Å; L235-A277 HydrophobicContact CD1-CB 3.82Å; L235-A277 HydrophobicContact CD2-CB 4.28Å; I273-A277 HydrophobicContact CG2-CB 3.79Å; S274-A277 WeakPolarHBondContact O-CB 3.43Å; S274-A277 PolarHBondContact O-N 3.27Å; S274-A277 PolarHBondContact OG-N 3.2Å; S274-A277 VanDerWaalsContact OG-N 3.11Å; A277-D279 VanDerWaalsContact C-N 3.29Å; A277-D279 PolarHBondContact O-N 2.89Å; A277-V280 WeakPolarHBondContact O-CG1 3.48Å; A277-V281 WeakPolarHBondContact O-CG2 3.37Å; A277-V281 PolarHBondContact O-N 3.41Å; A277-W303 HydrophobicContact CB-CD2 4.38Å; A277-W303 HydrophobicContact CB-CG 4.42Å; A277-W303 HydrophobicContact CB-CZ2 4.33Å
278K95.4Very high90.7Very high30 Ų3052.8 Ų52.813%0.1326%0.255CS..Hα-helixtrans-61.8-39.3174.6-67.1169.8-175.1167.90111.4F265 W270 I273 S274 E275 V281 R282F265-K278 HydrophobicContact CD1-CG 4.24Å; F265-K278 HydrophobicContact CD2-CB 4.43Å; F265-K278 HydrophobicContact CD2-CD 4.42Å; F265-K278 HydrophobicContact CD2-CG 4.3Å; F265-K278 HydrophobicContact CE1-CB 4.37Å; F265-K278 HydrophobicContact CE1-CG 4.21Å; F265-K278 HydrophobicContact CE2-CB 3.98Å; F265-K278 HydrophobicContact CE2-CG 4.29Å; F265-K278 HydrophobicContact CG-CD 4.44Å; F265-K278 HydrophobicContact CG-CG 4.25Å; F265-K278 HydrophobicContact CZ-CB 3.92Å; F265-K278 HydrophobicContact CZ-CG 4.21Å; W270-K278 HydrophobicContact CE3-CD 4.42Å; W270-K278 HydrophobicContact CE3-CG 3.77Å; W270-K278 HydrophobicContact CZ3-CG 3.94Å; W270-K278 VanDerWaalsContact O-CE 3.23Å; W270-K278 WeakPolarHBondContact O-CE 3.49Å; W270-K278 PolarHBondContact O-NZ 3.34Å; I273-K278 WeakPolarHBondContact O-CE 3.41Å; I273-K278 PolarHBondContact O-NZ 3.23Å; S274-K278 PolarHBondContact O-N 2.87Å; S274-K278 VanDerWaalsContact O-N 3.17Å; E275-K278 PolarHBondContact O-N 3.49Å; E275-K278 WeakPolarHBondContact OE2-CD 3.32Å; K278-V281 PolarHBondContact O-N 3.42Å; K278-R282 WeakPolarHBondContact O-CG 3.49Å; K278-R282 PolarHBondContact O-N 2.95Å
279D95.9Very high90Very high35 Ų3546.1 Ų46.119%0.18723%0.227CC..Hα-helixtrans-65.7-45.8-178.4-169.860.5000113.2E275 M276 A277 V281 R282 K283 H301E275-D279 VanDerWaalsContact O-CB 3.27Å; E275-D279 WeakPolarHBondContact O-CB 3.47Å; E275-D279 PolarHBondContact O-N 3.36Å; M276-D279 PolarHBondContact O-N 3.34Å; A277-D279 VanDerWaalsContact C-N 3.29Å; A277-D279 PolarHBondContact O-N 2.89Å; D279-V281 VanDerWaalsContact C-N 3.28Å; D279-V281 PolarHBondContact O-N 3.41Å; D279-R282 PolarHBondContact O-N 3.05Å; D279-R282 IonicContact OD1-CZ 2.78Å; D279-R282 IonicContact OD1-NH1 2.68Å; D279-R282 PolarHBondContact OD1-NH1 3.02Å; D279-R282 IonicContact OD1-NH2 3.61Å; D279-R282 PolarHBondContact OD1-NH2 2.92Å; D279-K283 WeakPolarHBondContact O-CG 3.46Å; D279-K283 PolarHBondContact O-N 3.49Å; D279-K283 WeakPolarHBondContact OD2-CE 3.43Å; D279-K283 IonicContact OD2-NZ 3.43Å; D279-K283 PolarHBondContact OD2-NZ 3.27Å; D279-H301 IonicContact OD2-CE1 2.72Å; D279-H301 IonicContact OD2-NE2 2.68Å; D279-H301 PolarHBondContact OD2-NE2 3.38Å; D279-H301 VanDerWaalsContact OD2-NE2 3.15Å
280V96.4Very high89.3Confident0 Ų049 Ų490%024%0.24CC..Hα-helixtrans-62-39.3176.768.80000111.2I231 M276 A277 K283 L284 L293 W303I231-V280 HydrophobicContact CG2-CG1 4.49Å; M276-V280 PolarHBondContact O-N 2.96Å; A277-V280 WeakPolarHBondContact O-CG1 3.48Å; V280-K283 PolarHBondContact O-N 3.24Å; V280-L284 HydrophobicContact CG2-CD1 3.96Å; V280-L284 HydrophobicContact CG2-CG 4.49Å; V280-L284 WeakPolarHBondContact O-CB 3.34Å; V280-L284 WeakPolarHBondContact O-CG 3.43Å; V280-L284 PolarHBondContact O-N 3.02Å; V280-L293 HydrophobicContact CG2-CD2 4.09Å; V280-W303 HydrophobicContact CG1-CD2 4.11Å; V280-W303 HydrophobicContact CG1-CE3 3.6Å; V280-W303 HydrophobicContact CG1-CZ3 4.14Å
281V95.9Very high88.9Confident0 Ų053.5 Ų53.50%026%0.261CS..Hα-helixtrans-64.8-46.7176.7172.30000111I231 Y232 L235 F263 F265 A277 K278 D279 K283 L284 L285I231-V281 HydrophobicContact CB-CG2 4.11Å; I231-V281 HydrophobicContact CG2-CG2 3.5Å; Y232-V281 HydrophobicContact CD2-CG1 3.87Å; L235-V281 HydrophobicContact CD1-CG2 4.2Å; F263-V281 HydrophobicContact CE2-CG1 3.93Å; F263-V281 HydrophobicContact CZ-CG1 4.18Å; F265-V281 HydrophobicContact CE1-CB 4.48Å; F265-V281 HydrophobicContact CE1-CG1 4.09Å; F265-V281 HydrophobicContact CZ-CB 4.39Å; F265-V281 HydrophobicContact CZ-CG1 4.17Å; A277-V281 WeakPolarHBondContact O-CG2 3.37Å; A277-V281 PolarHBondContact O-N 3.41Å; K278-V281 PolarHBondContact O-N 3.42Å; D279-V281 VanDerWaalsContact C-N 3.28Å; D279-V281 PolarHBondContact O-N 3.41Å; V281-K283 VanDerWaalsContact C-N 3.28Å; V281-K283 PolarHBondContact O-N 3.42Å; V281-L284 PolarHBondContact O-N 3.3Å; V281-L285 HydrophobicContact CG1-CD1 3.78Å; V281-L285 HydrophobicContact CG1-CG 4.31Å; V281-L285 WeakPolarHBondContact O-CB 3.19Å; V281-L285 PolarHBondContact O-N 2.95Å
282R94.9Very high88.8Confident86 Ų8650.6 Ų50.633%0.32524%0.239SC..Hα-helixtrans-57-40.6175.1-77.2-172.5-80.793-3.1112.3F263 F265 E275 K278 D279F263-R282 HydrophobicContact CZ-CG 4.31Å; F265-R282 HydrophobicContact CE2-CG 3.69Å; F265-R282 HydrophobicContact CZ-CG 3.85Å; E275-R282 IonicContact OE1-CZ 2.91Å; E275-R282 IonicContact OE1-NE 3.9Å; E275-R282 IonicContact OE1-NH2 3.07Å; E275-R282 PolarHBondContact OE1-NH2 3.48Å; K278-R282 WeakPolarHBondContact O-CG 3.49Å; K278-R282 PolarHBondContact O-N 2.95Å; D279-R282 PolarHBondContact O-N 3.05Å; D279-R282 IonicContact OD1-CZ 2.78Å; D279-R282 IonicContact OD1-NH1 2.68Å; D279-R282 PolarHBondContact OD1-NH1 3.02Å; D279-R282 IonicContact OD1-NH2 3.61Å; D279-R282 PolarHBondContact OD1-NH2 2.92Å
283K94.8Very high88.9Confident77 Ų7745.7 Ų45.734%0.33522%0.217SC..Hα-helixtrans-74.2-30.3179.3-68.9171.5171.2165.50112.8D279 V280 V281 R292 L293D279-K283 WeakPolarHBondContact O-CG 3.46Å; D279-K283 PolarHBondContact O-N 3.49Å; D279-K283 WeakPolarHBondContact OD2-CE 3.43Å; D279-K283 IonicContact OD2-NZ 3.43Å; D279-K283 PolarHBondContact OD2-NZ 3.27Å; V280-K283 PolarHBondContact O-N 3.24Å; V281-K283 VanDerWaalsContact C-N 3.28Å; V281-K283 PolarHBondContact O-N 3.42Å; K283-R292 WeakPolarHBondContact O-CA 3.27Å; K283-L293 HydrophobicContact CB-CB 3.99Å; K283-L293 HydrophobicContact CB-CD2 4.19Å; K283-L293 HydrophobicContact CD-CD1 4.4Å; K283-L293 HydrophobicContact CD-CD2 4.48Å; K283-L293 PolarHBondContact O-N 2.72Å
284L92.6Very high88.8Confident0 Ų048.2 Ų48.20%023%0.233CC..Hα-helixtrans-80.9-31.5176.2-74.4170000113.8L224 L227 I231 V280 V281 K286 R292 L293 V298L224-L284 HydrophobicContact CB-CD2 3.95Å; L224-L284 WeakPolarHBondContact O-CD2 3.4Å; L227-L284 HydrophobicContact CD2-CD1 4.4Å; L227-L284 HydrophobicContact CG-CD1 4.3Å; I231-L284 HydrophobicContact CD1-CD1 3.55Å; V280-L284 HydrophobicContact CG2-CD1 3.96Å; V280-L284 HydrophobicContact CG2-CG 4.49Å; V280-L284 WeakPolarHBondContact O-CB 3.34Å; V280-L284 WeakPolarHBondContact O-CG 3.43Å; V280-L284 PolarHBondContact O-N 3.02Å; V281-L284 PolarHBondContact O-N 3.3Å; L284-K286 VanDerWaalsContact C-N 3.3Å; L284-K286 PolarHBondContact O-N 3.26Å; L284-R292 WeakPolarHBondContact O-CD 3.11Å; L284-R292 WeakPolarHBondContact O-CG 3.44Å; L284-R292 PolarHBondContact O-NE 3.2Å; L284-R292 VanDerWaalsContact O-NE 3.13Å; L284-L293 HydrophobicContact CD2-CB 4.05Å; L284-L293 HydrophobicContact CG-CB 4.4Å; L284-V298 HydrophobicContact CD1-CG2 4.28Å; L284-V298 HydrophobicContact CD2-CG2 3.65Å; L284-V298 HydrophobicContact CG-CG2 4.29Å
285L89.3Confident88.8Confident3 Ų347.8 Ų47.82%0.01623%0.228CC..SBendtrans-93.723.8-179.1-61.9-176.2000113.5W225 V229 P240 F241 F263 V281 V287W225-L285 HydrophobicContact CD2-CD2 3.94Å; W225-L285 HydrophobicContact CE3-CD2 4.22Å; W225-L285 HydrophobicContact CG-CD2 4.31Å; W225-L285 HydrophobicContact CZ2-CD2 4.4Å; W225-L285 HydrophobicContact CZ3-CB 4.49Å; W225-L285 WeakPolarHBondContact CZ3-O 3.49Å; W225-L285 WeakPolarHBondContact O-CD2 3.19Å; V229-L285 HydrophobicContact CG2-CD2 3.86Å; P240-L285 HydrophobicContact CB-CD1 4.14Å; P240-L285 HydrophobicContact CG-CD1 4.04Å; F241-L285 HydrophobicContact CZ-CD1 4.44Å; F263-L285 HydrophobicContact CD1-CB 4.28Å; F263-L285 HydrophobicContact CD1-CD1 4.17Å; F263-L285 HydrophobicContact CD2-CD1 4.48Å; F263-L285 HydrophobicContact CE1-CB 3.47Å; F263-L285 VanDerWaalsContact CE1-CB 3.47Å; F263-L285 HydrophobicContact CE1-CD1 3.87Å; F263-L285 HydrophobicContact CE1-CG 4.31Å; F263-L285 HydrophobicContact CE2-CD1 4.17Å; F263-L285 HydrophobicContact CG-CD1 4.47Å; F263-L285 HydrophobicContact CZ-CB 3.83Å; F263-L285 HydrophobicContact CZ-CD1 3.85Å; F263-L285 HydrophobicContact CZ-CG 4.4Å; V281-L285 HydrophobicContact CG1-CD1 3.78Å; V281-L285 HydrophobicContact CG1-CG 4.31Å; V281-L285 WeakPolarHBondContact O-CB 3.19Å; V281-L285 PolarHBondContact O-N 2.95Å; L285-V287 PolarHBondContact O-N 3.46Å
286K85.3Confident88.8Confident90 Ų9045.9 Ų45.939%0.39122%0.22SC..  trans-64.3129.1168.4-74-70.5-171.2164.40110.4L284 E291 R292L284-K286 VanDerWaalsContact C-N 3.3Å; L284-K286 PolarHBondContact O-N 3.26Å; K286-E291 HydrophobicContact CB-CB 4.18Å; K286-E291 HydrophobicContact CD-CB 4.38Å; K286-E291 HydrophobicContact CG-CB 4.24Å; K286-E291 IonicContact NZ-OE2 3.15Å; K286-R292 HydrophobicContact CB-CB 4.33Å; K286-R292 PolarHBondContact O-NE 3.41Å; K286-R292 PolarHBondContact O-NH2 2.76Å
287V76.8Confident88.8Confident65 Ų6543.8 Ų43.839%0.39421%0.214SC..SBendtrans-59.5-52-180178.70000110.7M259 T260 L285 P289 R292M259-V287 WeakPolarHBondContact O-CG1 3.25Å; T260-V287 VanDerWaalsContact C-CG2 3.41Å; L285-V287 PolarHBondContact O-N 3.46Å; V287-P289 VanDerWaalsContact O-CD 3.27Å; V287-P289 WeakPolarHBondContact O-CD 2.99Å; V287-R292 PolarHBondContact O-NH2 3.15Å
288K73.4Confident88.8Confident108 Ų10843.8 Ų43.847%0.4721%0.214SC..SBendtrans-69.6116.8177.8-73.7-176.8-172.51710109.1E290 E291 R292K288-E290 HydrophobicContact CB-CG 4.45Å; K288-E290 PolarHBondContact O-N 3.26Å; K288-E291 HydrophobicContact CB-CB 4.3Å; K288-E291 HydrophobicContact CB-CG 4.05Å; K288-E291 HydrophobicContact CD-CG 4.39Å; K288-E291 VanDerWaalsContact CD-OE1 3.32Å; K288-E291 WeakPolarHBondContact CD-OE1 3.41Å; K288-E291 IonicContact NZ-OE1 3.75Å; K288-E291 PolarHBondContact NZ-OE1 3.46Å; K288-E291 PolarHBondContact O-N 3.22Å; K288-E291 VanDerWaalsContact O-N 3.11Å; K288-R292 PolarHBondContact O-N 3.38Å
289P73.6Confident88.9Confident30 Ų3042.9 Ų42.920%0.19521%0.21CC..G310 helixtrans-52.8-41.5-179.1-28.437.6000112.2Y216 V287 E291 R292Y216-P289 HydrophobicContact CD1-CB 4.48Å; Y216-P289 HydrophobicContact CE1-CB 3.53Å; Y216-P289 WeakPolarHBondContact CE1-O 3.2Å; Y216-P289 PolarHBondContact OH-O 3.04Å; V287-P289 VanDerWaalsContact O-CD 3.27Å; V287-P289 WeakPolarHBondContact O-CD 2.99Å; P289-E291 VanDerWaalsContact C-N 3.27Å; P289-E291 PolarHBondContact O-N 3.26Å; P289-R292 WeakPolarHBondContact O-CB 3.46Å; P289-R292 PolarHBondContact O-N 3.12Å
290E72.1Confident88.9Confident96 Ų9646.8 Ų46.845%0.44923%0.231SC..G310 helixtrans-66.7-20.9-178.165.3-87.5-153.900115.2K288 R292K288-E290 HydrophobicContact CB-CG 4.45Å; K288-E290 PolarHBondContact O-N 3.26Å; E290-R292 VanDerWaalsContact C-N 3.35Å
291E82.4Confident88.9Confident97 Ų9747.2 Ų47.245%0.45323%0.233SC..G310 helixtrans-89.6-8.3174.5-64.6-178.3-169.800111.9K286 K288 P289K286-E291 HydrophobicContact CB-CB 4.18Å; K286-E291 HydrophobicContact CD-CB 4.38Å; K286-E291 HydrophobicContact CG-CB 4.24Å; K286-E291 IonicContact NZ-OE2 3.15Å; K288-E291 HydrophobicContact CB-CB 4.3Å; K288-E291 HydrophobicContact CB-CG 4.05Å; K288-E291 HydrophobicContact CD-CG 4.39Å; K288-E291 VanDerWaalsContact CD-OE1 3.32Å; K288-E291 WeakPolarHBondContact CD-OE1 3.41Å; K288-E291 IonicContact NZ-OE1 3.75Å; K288-E291 PolarHBondContact NZ-OE1 3.46Å; K288-E291 PolarHBondContact O-N 3.22Å; K288-E291 VanDerWaalsContact O-N 3.11Å; P289-E291 VanDerWaalsContact C-N 3.27Å; P289-E291 PolarHBondContact O-N 3.26Å
292R88.4Confident88.7Confident12 Ų1250.8 Ų50.85%0.04526%0.256CS..SBendtrans-75.9141.8-176.9-166.7175.2-61.8134.912.9110.3Y216 S221 L224 K283 L284 K286 V287 K288 P289 E290 T294Y216-R292 WeakPolarHBondContact OH-CB 3.35Å; S221-R292 VanDerWaalsContact C-NH1 3.27Å; S221-R292 PolarHBondContact O-NH1 3.04Å; S221-R292 PolarHBondContact OG-NH1 2.86Å; L224-R292 HydrophobicContact CB-CG 4.46Å; K283-R292 WeakPolarHBondContact O-CA 3.27Å; L284-R292 WeakPolarHBondContact O-CD 3.11Å; L284-R292 WeakPolarHBondContact O-CG 3.44Å; L284-R292 PolarHBondContact O-NE 3.2Å; L284-R292 VanDerWaalsContact O-NE 3.13Å; K286-R292 HydrophobicContact CB-CB 4.33Å; K286-R292 PolarHBondContact O-NE 3.41Å; K286-R292 PolarHBondContact O-NH2 2.76Å; V287-R292 PolarHBondContact O-NH2 3.15Å; K288-R292 PolarHBondContact O-N 3.38Å; P289-R292 WeakPolarHBondContact O-CB 3.46Å; P289-R292 PolarHBondContact O-N 3.12Å; E290-R292 VanDerWaalsContact C-N 3.35Å; R292-T294 PolarHBondContact O-N 2.92Å
293L90.6Very high88.7Confident29 Ų2946.8 Ų46.815%0.15224%0.241CC..PPolyproline II helixtrans-54.2134.1174.8-160.357.3000110.5L224 V280 K283 L284 V298L224-L293 WeakPolarHBondContact CD1-O 3.49Å; V280-L293 HydrophobicContact CG2-CD2 4.09Å; K283-L293 HydrophobicContact CB-CB 3.99Å; K283-L293 HydrophobicContact CB-CD2 4.19Å; K283-L293 HydrophobicContact CD-CD1 4.4Å; K283-L293 HydrophobicContact CD-CD2 4.48Å; K283-L293 PolarHBondContact O-N 2.72Å; L284-L293 HydrophobicContact CD2-CB 4.05Å; L284-L293 HydrophobicContact CG-CB 4.4Å; L293-V298 HydrophobicContact CB-CG2 4.37Å; L293-V298 HydrophobicContact CD2-CB 4.39Å; L293-V298 HydrophobicContact CD2-CG2 3.72Å; L293-V298 HydrophobicContact CG-CG2 3.98Å
294T90.1Very high88.6Confident59 Ų5943.5 Ų43.536%0.36223%0.227SC..PPolyproline II helixtrans-77.2165.8173.863.80000110.8Y216 R292 E296 G297 V298Y216-T294 HydrophobicContact CD2-CG2 4.46Å; R292-T294 PolarHBondContact O-N 2.92Å; T294-E296 VanDerWaalsContact C-N 3.32Å; T294-E296 PolarHBondContact O-N 2.73Å; T294-G297 CarbonylContact O-C 3.58Å; T294-G297 WeakPolarHBondContact O-CA 3.46Å; T294-G297 PolarHBondContact O-N 3.1Å; T294-G297 VanDerWaalsContact O-N 3.12Å; T294-G297 PolarHBondContact OG1-N 3.02Å; T294-G297 VanDerWaalsContact OG1-N 3.16Å; T294-V298 WeakPolarHBondContact O-CG2 3.42Å; T294-V298 PolarHBondContact O-N 3.35Å
295I93.8Very high88.4Confident14 Ų1447 Ų477%0.07225%0.246CC..Hα-helixtrans-62.3-38.1179.2-166.660.3000112.9A133 L136 R137 L224 V298 L299A133-I295 HydrophobicContact CB-CD1 4.02Å; A133-I295 WeakPolarHBondContact O-CD1 3.4Å; L136-I295 HydrophobicContact CB-CD1 3.89Å; L136-I295 HydrophobicContact CB-CG1 4.42Å; L136-I295 HydrophobicContact CD1-CD1 4.47Å; R137-I295 HydrophobicContact CB-CG1 3.78Å; R137-I295 HydrophobicContact CB-CG2 4.44Å; R137-I295 HydrophobicContact CG-CG2 4.41Å; L224-I295 HydrophobicContact CD2-CB 4.09Å; L224-I295 HydrophobicContact CD2-CD1 3.76Å; L224-I295 HydrophobicContact CD2-CG1 4.49Å; I295-V298 WeakPolarHBondContact O-CB 3.18Å; I295-V298 PolarHBondContact O-N 2.95Å; I295-L299 PolarHBondContact O-N 3.22Å; I295-L299 VanDerWaalsContact O-N 3.11Å
296E93.1Very high87.9Confident71 Ų7148.9 Ų48.933%0.33226%0.259SS..Hα-helixtrans-65.8-42.5172.9-56.7-51.1147.300110.7R137 T294 V298 L299 D300R137-E296 WeakPolarHBondContact CD-OE1 3.46Å; R137-E296 WeakPolarHBondContact CD-OE2 3.25Å; R137-E296 VanDerWaalsContact CG-OE1 3.28Å; R137-E296 WeakPolarHBondContact CG-OE1 3.29Å; R137-E296 IonicContact NH1-OE2 2.97Å; T294-E296 VanDerWaalsContact C-N 3.32Å; T294-E296 PolarHBondContact O-N 2.73Å; E296-V298 PolarHBondContact O-N 3.42Å; E296-L299 PolarHBondContact O-N 2.96Å; E296-D300 WeakPolarHBondContact O-CB 3.25Å; E296-D300 PolarHBondContact O-N 3.37Å
297G94.5Very high86.8Confident18 Ų1851.3 Ų51.319%0.18628%0.282CS..Hα-helixtrans-60.8-30.3175.200000113.8T294 H301T294-G297 CarbonylContact O-C 3.58Å; T294-G297 WeakPolarHBondContact O-CA 3.46Å; T294-G297 PolarHBondContact O-N 3.1Å; T294-G297 VanDerWaalsContact O-N 3.12Å; T294-G297 PolarHBondContact OG1-N 3.02Å; T294-G297 VanDerWaalsContact OG1-N 3.16Å; G297-H301 WeakPolarHBondContact O-CB 3.4Å; G297-H301 PolarHBondContact O-N 3.2Å
298V96.3Very high86.3Confident0 Ų055.6 Ų55.60%030%0.298CS..Hα-helixtrans-68.3-49.2171.3173.80000110.5A133 L227 L284 L293 T294 I295 E296 D300 H301 L304A133-V298 HydrophobicContact CB-CG1 4.06Å; L227-V298 HydrophobicContact CD2-CG1 4.12Å; L227-V298 HydrophobicContact CD2-CG2 4.48Å; L284-V298 HydrophobicContact CD1-CG2 4.28Å; L284-V298 HydrophobicContact CD2-CG2 3.65Å; L284-V298 HydrophobicContact CG-CG2 4.29Å; L293-V298 HydrophobicContact CB-CG2 4.37Å; L293-V298 HydrophobicContact CD2-CB 4.39Å; L293-V298 HydrophobicContact CD2-CG2 3.72Å; L293-V298 HydrophobicContact CG-CG2 3.98Å; T294-V298 WeakPolarHBondContact O-CG2 3.42Å; T294-V298 PolarHBondContact O-N 3.35Å; I295-V298 WeakPolarHBondContact O-CB 3.18Å; I295-V298 PolarHBondContact O-N 2.95Å; E296-V298 PolarHBondContact O-N 3.42Å; V298-D300 VanDerWaalsContact C-N 3.29Å; V298-D300 PolarHBondContact O-N 3.05Å; V298-H301 WeakPolarHBondContact O-CB 3.42Å; V298-H301 PolarHBondContact O-N 3.46Å; V298-L304 HydrophobicContact CG1-CD1 4.41Å; V298-L304 HydrophobicContact CG1-CD2 3.98Å; V298-L304 WeakPolarHBondContact O-CD2 3.42Å
299L96.3Very high85.6Confident10 Ų1053.7 Ų53.75%0.05230%0.302CS..Hα-helixtrans-66.8-30.6-177.4-73.2167.4000112.9K130 A133 L134 R137 I295 E296 H301 L304 N305K130-L299 HydrophobicContact CG-CD2 4.48Å; A133-L299 HydrophobicContact CB-CD2 3.69Å; A133-L299 HydrophobicContact CB-CG 4.1Å; L134-L299 HydrophobicContact CD2-CD1 4.33Å; L134-L299 HydrophobicContact CD2-CD2 3.97Å; L134-L299 HydrophobicContact CG-CD2 4.06Å; R137-L299 HydrophobicContact CB-CD1 3.97Å; R137-L299 VanDerWaalsContact CD-CD1 3.49Å; R137-L299 HydrophobicContact CG-CD1 4.24Å; I295-L299 PolarHBondContact O-N 3.22Å; I295-L299 VanDerWaalsContact O-N 3.11Å; E296-L299 PolarHBondContact O-N 2.96Å; L299-H301 VanDerWaalsContact C-N 3.31Å; L299-L304 HydrophobicContact CD2-CD2 4.46Å; L299-N305 PolarHBondContact O-ND2 3.02Å
300D95.8Very high85.6Confident117 Ų11753.2 Ų53.263%0.62630%0.298SS*.THydrogen-bonded Turntrans-82.9-10.2174.1-67.1-21.3000112.6E296 V298E296-D300 WeakPolarHBondContact O-CB 3.25Å; E296-D300 PolarHBondContact O-N 3.37Å; V298-D300 VanDerWaalsContact C-N 3.29Å; V298-D300 PolarHBondContact O-N 3.05Å
301H95.9Very high86Confident10 Ų1052.8 Ų52.85%0.04630%0.299CS..SBendtrans-61.3133.1-175.4-163.4-92.6000110.8M276 D279 G297 V298 L299 W303 L304M276-H301 PolarHBondContact O-CE1 3.07Å; D279-H301 IonicContact OD2-CE1 2.72Å; D279-H301 IonicContact OD2-NE2 2.68Å; D279-H301 PolarHBondContact OD2-NE2 3.38Å; D279-H301 VanDerWaalsContact OD2-NE2 3.15Å; G297-H301 WeakPolarHBondContact O-CB 3.4Å; G297-H301 PolarHBondContact O-N 3.2Å; V298-H301 WeakPolarHBondContact O-CB 3.42Å; V298-H301 PolarHBondContact O-N 3.46Å; L299-H301 VanDerWaalsContact C-N 3.31Å; H301-W303 VanDerWaalsContact ND1-CB 3.35Å; H301-W303 WeakPolarHBondContact ND1-CB 3.35Å; H301-W303 PolarHBondContact ND1-N 2.77Å; H301-W303 PolarHBondContact O-N 2.63Å; H301-L304 HydrophobicContact CB-CD1 4.27Å; H301-L304 PolarHBondContact O-N 3.11Å
302P93.6Very high86.2Confident75 Ų7551.4 Ų51.449%0.48730%0.295SS..Hα-helixtrans-53.2-32.1-178.5-32.338.4000114.2M276 L304 N305 S306M276-P302 HydrophobicContact CE-CB 3.24Å; M276-P302 WeakPolarHBondContact CE-O 3.27Å; P302-L304 PolarHBondContact O-N 2.99Å; P302-N305 CarbonylContact O-C 3.56Å; P302-N305 PolarHBondContact O-N 3.38Å; P302-S306 WeakPolarHBondContact O-CB 3.46Å; P302-S306 PolarHBondContact O-N 3.29Å
303W94.8Very high86.2Confident1 Ų154.7 Ų54.70%0.00432%0.316CS..Hα-helixtrans-59.7-31.3177-173.862.3000113.8E122 A125 S126 T129 I231 L235 M276 A277 V280 H301E122-W303 HydrophobicContact CG-CZ2 4.3Å; E122-W303 PolarHBondContact OE1-NE1 2.96Å; A125-W303 HydrophobicContact CB-CH2 4.37Å; A125-W303 HydrophobicContact CB-CZ2 4.29Å; S126-W303 PolarHBondContact OG-O 2.68Å; T129-W303 HydrophobicContact CG2-CZ3 3.93Å; I231-W303 HydrophobicContact CD1-CZ3 4.39Å; I231-W303 HydrophobicContact CG1-CZ3 4.43Å; I231-W303 HydrophobicContact CG2-CH2 3.88Å; I231-W303 HydrophobicContact CG2-CZ3 3.94Å; L235-W303 HydrophobicContact CD2-CZ2 4.08Å; M276-W303 HydrophobicContact CB-CB 4.04Å; M276-W303 HydrophobicContact CB-CG 4.42Å; A277-W303 HydrophobicContact CB-CD2 4.38Å; A277-W303 HydrophobicContact CB-CG 4.42Å; A277-W303 HydrophobicContact CB-CZ2 4.33Å; V280-W303 HydrophobicContact CG1-CD2 4.11Å; V280-W303 HydrophobicContact CG1-CE3 3.6Å; V280-W303 HydrophobicContact CG1-CZ3 4.14Å; H301-W303 VanDerWaalsContact ND1-CB 3.35Å; H301-W303 WeakPolarHBondContact ND1-CB 3.35Å; H301-W303 PolarHBondContact ND1-N 2.77Å; H301-W303 PolarHBondContact O-N 2.63Å
304L92.9Very high86.2Confident8 Ų853.6 Ų53.64%0.04231%0.31CS..Hα-helixtrans-88.5-16.6179.8-81.677.4000113T129 K130 V298 L299 H301 P302T129-L304 HydrophobicContact CG2-CD1 4.44Å; T129-L304 HydrophobicContact CG2-CD2 4.32Å; K130-L304 HydrophobicContact CB-CD2 4.05Å; K130-L304 HydrophobicContact CG-CD2 4.38Å; K130-L304 PolarHBondContact NZ-O 3Å; V298-L304 HydrophobicContact CG1-CD1 4.41Å; V298-L304 HydrophobicContact CG1-CD2 3.98Å; V298-L304 WeakPolarHBondContact O-CD2 3.42Å; L299-L304 HydrophobicContact CD2-CD2 4.46Å; H301-L304 HydrophobicContact CB-CD1 4.27Å; H301-L304 PolarHBondContact O-N 3.11Å; P302-L304 PolarHBondContact O-N 2.99Å
305N87.1Confident86.1Confident75 Ų7552.4 Ų52.440%0.40130%0.303SS..Hα-helixtrans-116.6-2-174.7-64-40.1000113.2K130 L299 P302 T307K130-N305 PolarHBondContact NZ-OD1 2.72Å; L299-N305 PolarHBondContact O-ND2 3.02Å; P302-N305 CarbonylContact O-C 3.56Å; P302-N305 PolarHBondContact O-N 3.38Å; N305-T307 PolarHBondContact O-N 2.66Å
306S78.5Confident85.7Confident41 Ų4151.8 Ų51.829%0.28730%0.3SS..  trans-62.8128177.5-170.10000110.6P302 E308P302-S306 WeakPolarHBondContact O-CB 3.46Å; P302-S306 PolarHBondContact O-N 3.29Å; S306-E308 PolarHBondContact OG-N 3.29Å
307T63.6Low85.3Confident142 Ų14248.5 Ų48.587%0.87129%0.285SS*.  trans-92-11.3170.952.60000112.1N305N305-T307 PolarHBondContact O-N 2.66Å
308E64.6Low84.8Confident154 Ų15454.8 Ų54.872%0.7231%0.31SS*.SBendtrans-67.2135.5171.9-67.2-176.8172.700109.1S306 L310S306-E308 PolarHBondContact OG-N 3.29Å; E308-L310 PolarHBondContact O-N 3.29Å
309A59.6Low84.1Confident68 Ų6858.3 Ų58.356%0.56233%0.328SS*.  trans-66.794.7-173.500000111.2D311A309-D311 WeakPolarHBondContact CB-OD2 3.4Å; A309-D311 PolarHBondContact O-N 2.95Å
310L74Confident83.5Confident21 Ų2157.8 Ų57.811%0.1133%0.325CS..  trans-73.652.2166.4-63.3173.7000110.4E122 K123 E308 N312E122-L310 CarbonylContact C-O 3.5Å; E122-L310 HydrophobicContact CB-CB 4.08Å; E122-L310 WeakPolarHBondContact CB-O 3.37Å; E122-L310 HydrophobicContact CG-CB 4.25Å; E122-L310 HydrophobicContact CG-CD1 4.48Å; E122-L310 PolarHBondContact N-O 3.38Å; K123-L310 HydrophobicContact CB-CB 4.23Å; K123-L310 WeakPolarHBondContact CB-O 3.47Å; K123-L310 PolarHBondContact N-O 3.34Å; E308-L310 PolarHBondContact O-N 3.29Å; L310-N312 PolarHBondContact O-N 2.82Å
311D79.3Confident82.8Confident87 Ų8757.3 Ų57.347%0.46532%0.321SS..  trans-85.311.5-173.6-68.7-17.8000112.6K123 A309 V313K123-D311 VanDerWaalsContact CD-OD1 3.25Å; K123-D311 WeakPolarHBondContact CD-OD1 3.33Å; A309-D311 WeakPolarHBondContact CB-OD2 3.4Å; A309-D311 PolarHBondContact O-N 2.95Å; D311-V313 PolarHBondContact O-N 3.45Å
312N86.6Confident81.9Confident68 Ų6861.1 Ų61.136%0.36434%0.341SS..PPolyproline II helixtrans-56.2124.8173.5-62.7-29.6000109.7T121 E122 Q272 L310 L314T121-N312 CarbonylContact C-O 3.48Å; T121-N312 VanDerWaalsContact CA-O 3.24Å; T121-N312 WeakPolarHBondContact CA-O 3.37Å; E122-N312 PolarHBondContact N-O 3.35Å; Q272-N312 PolarHBondContact O-ND2 3.33Å; Q272-N312 VanDerWaalsContact O-ND2 3.07Å; L310-N312 PolarHBondContact O-N 2.82Å; N312-L314 PolarHBondContact O-N 3.17Å
313V88.9Confident81Confident81 Ų8165.1 Ų65.149%0.49135%0.351SS..BIsolated β-bridgetrans-71.2123.1173.9-178.80000108.2D311D311-V313 PolarHBondContact O-N 3.45Å
314L90.6Very high80Confident5 Ų568.2 Ų68.23%0.02638%0.377CS..PPolyproline II helixtrans-81.2143.7-179.5-64.2172000110.9F120 E122 A125 L235 I273 N312 S316F120-L314 HydrophobicContact CD1-CB 4.42Å; F120-L314 HydrophobicContact CD1-CD1 3.6Å; F120-L314 HydrophobicContact CE1-CD1 3.75Å; F120-L314 WeakPolarHBondContact O-CB 3.49Å; F120-L314 PolarHBondContact O-N 2.82Å; E122-L314 HydrophobicContact CB-CD2 4Å; E122-L314 HydrophobicContact CB-CG 4.35Å; E122-L314 HydrophobicContact CG-CD2 4.45Å; A125-L314 HydrophobicContact CB-CD1 3.82Å; L235-L314 HydrophobicContact CD2-CD1 4.07Å; L235-L314 HydrophobicContact CD2-CD2 3.86Å; I273-L314 HydrophobicContact CD1-CD2 4.16Å; I273-L314 HydrophobicContact CG1-CD2 3.99Å; N312-L314 PolarHBondContact O-N 3.17Å; L314-S316 PolarHBondContact O-N 3.3Å
315P87.4Confident79.1Confident35 Ų3570.5 Ų70.523%0.22739%0.391CS..THydrogen-bonded Turntrans-70.2-16.3177.227.9-33.9000113.2L235 E269 A317 Q318 L319L235-P315 WeakPolarHBondContact O-CD 3.48Å; E269-P315 HydrophobicContact CB-CB 4.4Å; E269-P315 HydrophobicContact CB-CG 3.78Å; E269-P315 HydrophobicContact CG-CB 4.47Å; E269-P315 HydrophobicContact CG-CG 4.34Å; P315-A317 VanDerWaalsContact C-N 3.32Å; P315-A317 PolarHBondContact O-N 2.63Å; P315-Q318 PolarHBondContact O-N 2.79Å; P315-Q318 VanDerWaalsContact O-N 3.14Å; P315-L319 HydrophobicContact CB-CD1 4.33Å; P315-L319 PolarHBondContact O-N 3.06Å; P315-L319 VanDerWaalsContact O-N 3.1Å
316S86.4Confident78.6Confident0 Ų067.4 Ų67.40%038%0.375CS..Hα-helixtrans-56.4-41.1-177.156.90000113.7M234 L314 Q318 L319 M320M234-S316 WeakPolarHBondContact O-CB 3.47Å; M234-S316 PolarHBondContact O-OG 3.46Å; L314-S316 PolarHBondContact O-N 3.3Å; S316-Q318 VanDerWaalsContact C-N 3.3Å; S316-Q318 PolarHBondContact O-N 3.27Å; S316-L319 PolarHBondContact O-N 3Å; S316-M320 VanDerWaalsContact O-CB 3.25Å; S316-M320 WeakPolarHBondContact O-CB 3.4Å; S316-M320 WeakPolarHBondContact O-CG 3.36Å; S316-M320 PolarHBondContact O-N 3.02Å
317A85.7Confident78.5Confident2 Ų267.8 Ų67.82%0.01738%0.381CS..Hα-helixtrans-56.5-43.5177.700000112.4I114 H117 F120 P315 M321I114-A317 HydrophobicContact CG2-CB 4.48Å; H117-A317 WeakPolarHBondContact O-CB 3.28Å; F120-A317 HydrophobicContact CB-CB 3.94Å; P315-A317 VanDerWaalsContact C-N 3.32Å; P315-A317 PolarHBondContact O-N 2.63Å; A317-M321 WeakPolarHBondContact O-CG 3.13Å
318Q83.5Confident79Confident151 Ų15162.9 Ų62.971%0.70636%0.358SS*.Hα-helixtrans-73.8-43.8-179.3-174.2174.6-700111.9P315 S316 M320 M321P315-Q318 PolarHBondContact O-N 2.79Å; P315-Q318 VanDerWaalsContact O-N 3.14Å; S316-Q318 VanDerWaalsContact C-N 3.3Å; S316-Q318 PolarHBondContact O-N 3.27Å; Q318-M320 VanDerWaalsContact C-N 3.28Å; Q318-M320 PolarHBondContact O-N 2.91Å; Q318-M321 WeakPolarHBondContact O-CG 3.3Å; Q318-M321 PolarHBondContact O-N 3.5Å
319L81.9Confident79.6Confident73 Ų7355.9 Ų55.938%0.38233%0.326SS..Hα-helixtrans-67.6-29.2-179.3-72.9167.2000112.8C236 Y238 E269 P315 S316C236-L319 WeakPolarHBondContact O-CD1 3.37Å; Y238-L319 HydrophobicContact CD1-CD1 4.41Å; E269-L319 HydrophobicContact CG-CD1 4.06Å; P315-L319 HydrophobicContact CB-CD1 4.33Å; P315-L319 PolarHBondContact O-N 3.06Å; P315-L319 VanDerWaalsContact O-N 3.1Å; S316-L319 PolarHBondContact O-N 3Å
320M83.8Confident80.4Confident0 Ų054.2 Ų54.20%031%0.306CS..THydrogen-bonded Turntrans-86.1-0.9179.5-67.9-179.9172.500114.4F111 I114 S115 V233 S316 Q318 D322 V326 I329F111-M320 HydrophobicContact CB-CE 4.48Å; F111-M320 HydrophobicContact CB-SD 4.15Å; F111-M320 HydrophobicContact CD1-CE 3.97Å; F111-M320 HydrophobicContact CD1-SD 4.32Å; F111-M320 HydrophobicContact CD2-CE 4.37Å; F111-M320 HydrophobicContact CE1-CE 4.31Å; F111-M320 HydrophobicContact CG-CE 4.04Å; F111-M320 HydrophobicContact CG-SD 4.3Å; I114-M320 HydrophobicContact CB-SD 4.39Å; I114-M320 HydrophobicContact CG2-SD 3.97Å; S115-M320 WeakPolarHBondContact CB-O 3.38Å; V233-M320 HydrophobicContact CG1-CE 3.23Å; V233-M320 WeakPolarHBondContact O-CE 3.08Å; S316-M320 VanDerWaalsContact O-CB 3.25Å; S316-M320 WeakPolarHBondContact O-CB 3.4Å; S316-M320 WeakPolarHBondContact O-CG 3.36Å; S316-M320 PolarHBondContact O-N 3.02Å; Q318-M320 VanDerWaalsContact C-N 3.28Å; Q318-M320 PolarHBondContact O-N 2.91Å; M320-D322 PolarHBondContact O-N 3.25Å; M320-V326 HydrophobicContact CB-CG2 3.83Å; M320-V326 HydrophobicContact CG-CG2 4.25Å; M320-V326 VanDerWaalsContact O-CG2 3.25Å; M320-V326 WeakPolarHBondContact O-CG2 3.32Å; M320-I329 HydrophobicContact CE-CD1 4.17Å
321M79.5Confident80.6Confident107 Ų10758.5 Ų58.553%0.52733%0.325SS..THydrogen-bonded Turntrans-59.2-30.3178.4-71.4-173.517800112.5A317 Q318 K323A317-M321 WeakPolarHBondContact O-CG 3.13Å; Q318-M321 WeakPolarHBondContact O-CG 3.3Å; Q318-M321 PolarHBondContact O-N 3.5Å; M321-K323 PolarHBondContact O-N 3.33Å
322D77.3Confident80.3Confident90 Ų9055.2 Ų55.248%0.48131%0.31SS..SBendtrans-78.9116.1172.7-173.4-7.3000110.9M320 A324 V325 V326M320-D322 PolarHBondContact O-N 3.25Å; D322-A324 PolarHBondContact O-N 2.99Å; D322-A324 WeakPolarHBondContact OD1-CB 3.36Å; D322-A324 PolarHBondContact OD1-N 3Å; D322-V325 HydrophobicContact CB-CB 4.23Å; D322-V325 HydrophobicContact CB-CG2 3.82Å; D322-V325 WeakPolarHBondContact O-CB 3.48Å; D322-V325 PolarHBondContact O-N 3.02Å; D322-V326 PolarHBondContact O-N 3.39Å
323K74.3Confident79.6Confident158 Ų15852.1 Ų52.169%0.68729%0.294SS*.Hα-helixtrans-58.4-30.8176.8-68.8-175.5178.5-179.90112.8M321 V325 V326 A327M321-K323 PolarHBondContact O-N 3.33Å; K323-V325 VanDerWaalsContact C-N 3.33Å; K323-V326 PolarHBondContact O-N 3.48Å; K323-A327 WeakPolarHBondContact O-CB 3.44Å; K323-A327 PolarHBondContact O-N 3.45Å
324A74.5Confident78.9Confident66 Ų6650 Ų5055%0.54528%0.284SS..Hα-helixtrans-67.4-37177.300000111.5D322 A327 G328D322-A324 PolarHBondContact O-N 2.99Å; D322-A324 WeakPolarHBondContact OD1-CB 3.36Å; D322-A324 PolarHBondContact OD1-N 3Å; A324-A327 PolarHBondContact O-N 3.32Å; A324-G328 PolarHBondContact O-N 3.44Å
325V74.4Confident77.9Confident57 Ų5752.1 Ų52.135%0.34529%0.294SS..Hα-helixtrans-63.8-48.7174.9174.40000110D322 K323 A327 G328 I329D322-V325 HydrophobicContact CB-CB 4.23Å; D322-V325 HydrophobicContact CB-CG2 3.82Å; D322-V325 WeakPolarHBondContact O-CB 3.48Å; D322-V325 PolarHBondContact O-N 3.02Å; K323-V325 VanDerWaalsContact C-N 3.33Å; V325-A327 VanDerWaalsContact C-N 3.34Å; V325-A327 PolarHBondContact O-N 3.5Å; V325-G328 PolarHBondContact O-N 3Å; V325-G328 VanDerWaalsContact O-N 3.16Å; V325-I329 HydrophobicContact CG1-CD1 3.91Å; V325-I329 VanDerWaalsContact O-CG1 3.27Å; V325-I329 WeakPolarHBondContact O-CG1 3.44Å; V325-I329 PolarHBondContact O-N 2.96Å
326V75.6Confident77Confident9 Ų950.7 Ų50.76%0.05529%0.285CS..Hα-helixtrans-58.5-45.3177.8179.20000111.7F111 M320 D322 K323 G328 I329 Q330F111-V326 HydrophobicContact CB-CG1 4.04Å; M320-V326 HydrophobicContact CB-CG2 3.83Å; M320-V326 HydrophobicContact CG-CG2 4.25Å; M320-V326 VanDerWaalsContact O-CG2 3.25Å; M320-V326 WeakPolarHBondContact O-CG2 3.32Å; D322-V326 PolarHBondContact O-N 3.39Å; K323-V326 PolarHBondContact O-N 3.48Å; V326-G328 VanDerWaalsContact C-N 3.34Å; V326-G328 PolarHBondContact O-N 3.39Å; V326-I329 PolarHBondContact O-N 2.92Å; V326-Q330 WeakPolarHBondContact O-CG 3.42Å; V326-Q330 PolarHBondContact O-N 3.31Å
327A77.4Confident76.1Confident50 Ų5050.9 Ų50.941%0.41329%0.285SS..Hα-helixtrans-62.3-40.1177.300000112.5K323 A324 V325 Q330 Q331K323-A327 WeakPolarHBondContact O-CB 3.44Å; K323-A327 PolarHBondContact O-N 3.45Å; A324-A327 PolarHBondContact O-N 3.32Å; V325-A327 VanDerWaalsContact C-N 3.34Å; V325-A327 PolarHBondContact O-N 3.5Å; A327-Q330 PolarHBondContact O-N 3.04Å; A327-Q331 WeakPolarHBondContact O-CB 3.47Å; A327-Q331 PolarHBondContact O-N 3.23Å
328G74.6Confident75.2Confident38 Ų3853.3 Ų53.339%0.39231%0.305SS..Hα-helixtrans-63.4-39.4175.500000112.9A324 V325 V326 A332A324-G328 PolarHBondContact O-N 3.44Å; V325-G328 PolarHBondContact O-N 3Å; V325-G328 VanDerWaalsContact O-N 3.16Å; V326-G328 VanDerWaalsContact C-N 3.34Å; V326-G328 PolarHBondContact O-N 3.39Å; G328-A332 WeakPolarHBondContact O-CB 3.38Å; G328-A332 PolarHBondContact O-N 2.86Å
329I75.9Confident74.2Confident8 Ų851.5 Ų51.54%0.04130%0.301CS..Hα-helixtrans-64.4-47175.7-63.9162.7000111F111 V233 G237 M320 V325 V326 Q331 A332 H333F111-I329 HydrophobicContact CD2-CG2 4.28Å; F111-I329 HydrophobicContact CE2-CG2 3.93Å; V233-I329 HydrophobicContact CG1-CD1 4.47Å; V233-I329 HydrophobicContact CG1-CG2 3.81Å; V233-I329 HydrophobicContact CG2-CG2 4.11Å; G237-I329 WeakPolarHBondContact O-CD1 3.34Å; M320-I329 HydrophobicContact CE-CD1 4.17Å; V325-I329 HydrophobicContact CG1-CD1 3.91Å; V325-I329 VanDerWaalsContact O-CG1 3.27Å; V325-I329 WeakPolarHBondContact O-CG1 3.44Å; V325-I329 PolarHBondContact O-N 2.96Å; V326-I329 PolarHBondContact O-N 2.92Å; I329-Q331 PolarHBondContact O-N 3.4Å; I329-A332 PolarHBondContact O-N 3.45Å; I329-H333 PolarHBondContact O-N 2.96Å
330Q77.5Confident73.2Confident33 Ų3349.3 Ų49.315%0.15429%0.289CS..Hα-helixtrans-57.8-48.9177.5-75.6176.4-28.500111.1E109 E152 V326 A327 A332 H333 A334E109-Q330 PolarHBondContact OE2-NE2 2.97Å; E152-Q330 HydrophobicContact CG-CG 4.37Å; E152-Q330 WeakPolarHBondContact OE1-CB 3.4Å; V326-Q330 WeakPolarHBondContact O-CG 3.42Å; V326-Q330 PolarHBondContact O-N 3.31Å; A327-Q330 PolarHBondContact O-N 3.04Å; Q330-A332 PolarHBondContact O-N 3.14Å; Q330-H333 PolarHBondContact O-N 3.39Å; Q330-A334 WeakPolarHBondContact O-CB 3.39Å; Q330-A334 PolarHBondContact O-N 2.92Å
331Q77.4Confident72.2Confident110 Ų11051.1 Ų51.151%0.51430%0.296SS..Hα-helixtrans-58.8-47.9177-176.4179-9.600112A327 I329 H333 A334 E335A327-Q331 WeakPolarHBondContact O-CB 3.47Å; A327-Q331 PolarHBondContact O-N 3.23Å; I329-Q331 PolarHBondContact O-N 3.4Å; Q331-H333 VanDerWaalsContact C-N 3.33Å; Q331-H333 PolarHBondContact O-N 2.82Å; Q331-A334 PolarHBondContact O-N 3.43Å; Q331-E335 WeakPolarHBondContact CG-OE1 3.47Å; Q331-E335 PolarHBondContact NE2-OE1 3.28Å; Q331-E335 WeakPolarHBondContact O-CG 3.43Å; Q331-E335 PolarHBondContact O-N 3.04Å
332A72.3Confident71.1Confident18 Ų1848.7 Ų48.715%0.14928%0.284CS..Hα-helixtrans-60.5-41.6-179.600000112.2M254 G328 I329 Q330 Q336M254-A332 HydrophobicContact CE-CB 4.41Å; G328-A332 WeakPolarHBondContact O-CB 3.38Å; G328-A332 PolarHBondContact O-N 2.86Å; I329-A332 PolarHBondContact O-N 3.45Å; Q330-A332 PolarHBondContact O-N 3.14Å; A332-Q336 WeakPolarHBondContact O-CB 3.45Å; A332-Q336 PolarHBondContact O-N 3.36Å
333H73.5Confident69.8Low4 Ų451.1 Ų51.12%0.01929%0.293CS..Hα-helixtrans-69.9-41.5178.2-168.3-173.6000111.8L149 P151 S226 I329 Q330 Q331 E335 Q336 L337L149-H333 PolarHBondContact O-CE1 2.82Å; P151-H333 WeakPolarHBondContact CD-ND1 3.38Å; S226-H333 PolarHBondContact OG-NE2 2.97Å; I329-H333 PolarHBondContact O-N 2.96Å; Q330-H333 PolarHBondContact O-N 3.39Å; Q331-H333 VanDerWaalsContact C-N 3.33Å; Q331-H333 PolarHBondContact O-N 2.82Å; H333-E335 VanDerWaalsContact C-N 3.33Å; H333-E335 PolarHBondContact O-N 2.97Å; H333-Q336 PolarHBondContact O-N 3.37Å; H333-L337 WeakPolarHBondContact O-CB 3.23Å; H333-L337 PolarHBondContact O-N 3.35Å
334A73.2Confident68.7Low35 Ų3547.9 Ų47.929%0.28928%0.283SS..Hα-helixtrans-59.6-42.4175.400000112.2Q330 Q331 L337 A338Q330-A334 WeakPolarHBondContact O-CB 3.39Å; Q330-A334 PolarHBondContact O-N 2.92Å; Q331-A334 PolarHBondContact O-N 3.43Å; A334-L337 PolarHBondContact O-N 3.19Å; A334-A338 PolarHBondContact O-N 3.41Å
335E69.4Low67.2Low51 Ų5150.7 Ų50.724%0.23829%0.288CS..Hα-helixtrans-65.7-40.6175.8-72.3179.6-164.800112.3I250 Q331 H333 A338 N339I250-E335 HydrophobicContact CD1-CB 4.09Å; I250-E335 HydrophobicContact CG1-CB 4.21Å; I250-E335 WeakPolarHBondContact CG1-OE2 3.46Å; Q331-E335 WeakPolarHBondContact CG-OE1 3.47Å; Q331-E335 PolarHBondContact NE2-OE1 3.28Å; Q331-E335 WeakPolarHBondContact O-CG 3.43Å; Q331-E335 PolarHBondContact O-N 3.04Å; H333-E335 VanDerWaalsContact C-N 3.33Å; H333-E335 PolarHBondContact O-N 2.97Å; E335-A338 PolarHBondContact O-N 3.27Å; E335-N339 PolarHBondContact O-N 2.92Å; E335-N339 PolarHBondContact O-ND2 3.46Å
336Q69.2Low65.6Low5 Ų557.7 Ų57.72%0.02331%0.314CS..Hα-helixtrans-61.8-46.9176.1179.4169.210.800111.5I258 A332 H333 A338 N339 M340I258-Q336 HydrophobicContact CD1-CG 4.06Å; A332-Q336 WeakPolarHBondContact O-CB 3.45Å; A332-Q336 PolarHBondContact O-N 3.36Å; H333-Q336 PolarHBondContact O-N 3.37Å; Q336-A338 PolarHBondContact O-N 2.94Å; Q336-N339 PolarHBondContact O-N 3.03Å; Q336-M340 HydrophobicContact CG-SD 4.16Å; Q336-M340 WeakPolarHBondContact O-CG 3.32Å; Q336-M340 PolarHBondContact O-N 2.97Å
337L67.9Low64Low3 Ų361.8 Ų61.82%0.01634%0.339CS..Hα-helixtrans-58.3-45175.4-88170000112.5L149 K150 S226 H333 A334 N339 M340 R341L149-L337 WeakPolarHBondContact O-CD1 3.49Å; K150-L337 HydrophobicContact CB-CD1 3.73Å; S226-L337 WeakPolarHBondContact OG-CD2 3.25Å; H333-L337 WeakPolarHBondContact O-CB 3.23Å; H333-L337 PolarHBondContact O-N 3.35Å; A334-L337 PolarHBondContact O-N 3.19Å; L337-N339 PolarHBondContact O-N 3.21Å; L337-M340 PolarHBondContact O-N 2.79Å; L337-M340 VanDerWaalsContact O-N 3.15Å; L337-R341 WeakPolarHBondContact O-CG 3.13Å; L337-R341 PolarHBondContact O-N 3.24Å
338A66.6Low62.3Low53 Ų5364.5 Ų64.544%0.43836%0.355SS..Hα-helixtrans-58.6-35.3179.100000112.5A334 E335 Q336A334-A338 PolarHBondContact O-N 3.41Å; E335-A338 PolarHBondContact O-N 3.27Å; Q336-A338 PolarHBondContact O-N 2.94Å
339N63.1Low61Low114 Ų11469.8 Ų69.861%0.6137%0.373SS*.Hα-helixtrans-80.1-28.6177.6-71.5-61.8000113.7I250 E335 Q336 L337I250-N339 WeakPolarHBondContact CD1-ND2 3.25Å; E335-N339 PolarHBondContact O-N 2.92Å; E335-N339 PolarHBondContact O-ND2 3.46Å; Q336-N339 PolarHBondContact O-N 3.03Å; L337-N339 PolarHBondContact O-N 3.21Å
340M60.9Low59.7Low27 Ų2776.5 Ų76.513%0.13340%0.402CS..Hα-helixtrans-80.9-19.6175.3-69.7-174.365.800112.8Y218 W225 Q336 L337 I342Y218-M340 WeakPolarHBondContact CE1-O 3.09Å; Y218-M340 PolarHBondContact OH-O 2.92Å; W225-M340 HydrophobicContact CB-CE 3.82Å; W225-M340 HydrophobicContact CD2-CE 3.82Å; W225-M340 HydrophobicContact CD2-SD 4.13Å; W225-M340 HydrophobicContact CG-CE 3.47Å; W225-M340 VanDerWaalsContact CG-CE 3.47Å; W225-M340 HydrophobicContact CG-SD 3.84Å; W225-M340 PolarHBondContact NE1-SD 3Å; W225-M340 VanDerWaalsContact NE1-SD 3.41Å; Q336-M340 HydrophobicContact CG-SD 4.16Å; Q336-M340 WeakPolarHBondContact O-CG 3.32Å; Q336-M340 PolarHBondContact O-N 2.97Å; L337-M340 PolarHBondContact O-N 2.79Å; L337-M340 VanDerWaalsContact O-N 3.15Å; M340-I342 PolarHBondContact O-N 3.47Å
341R61Low58.7Low37 Ų3778.5 Ų78.514%0.1442%0.418CS..SBendtrans-70.6125174.5-77.8176.7-171.9147.245.5110.6R147 D148 F172 L337 Q343R147-R341 VanDerWaalsContact O-CZ 3.24Å; R147-R341 PolarHBondContact O-NE 3.05Å; R147-R341 PolarHBondContact O-NH2 3.39Å; D148-R341 VanDerWaalsContact CB-NH2 3.29Å; D148-R341 IonicContact OD1-CZ 3.87Å; D148-R341 IonicContact OD1-NH1 3.56Å; D148-R341 IonicContact OD1-NH2 2.88Å; D148-R341 PolarHBondContact OD1-NH2 3.45Å; D148-R341 IonicContact OD2-NH1 3.59Å; D148-R341 IonicContact OD2-NH2 3.86Å; F172-R341 VanDerWaalsContact CE1-NH1 3.34Å; F172-R341 VanDerWaalsContact CG-NH1 3.28Å; F172-R341 VanDerWaalsContact CZ-NH1 3.26Å; L337-R341 WeakPolarHBondContact O-CG 3.13Å; L337-R341 PolarHBondContact O-N 3.24Å; R341-Q343 PolarHBondContact O-N 3.02Å
342I56.5Low57.4Low57 Ų5778.9 Ų78.929%0.29242%0.423SS..  trans-68.7114.1158.6-63.3169000106.7V194 Y218 M340 D344V194-I342 HydrophobicContact CG2-CD1 3.99Å; V194-I342 HydrophobicContact CG2-CG1 4.44Å; Y218-I342 HydrophobicContact CD1-CD1 3.41Å; Y218-I342 VanDerWaalsContact CD1-CD1 3.41Å; Y218-I342 HydrophobicContact CD1-CG1 3.97Å; Y218-I342 HydrophobicContact CE1-CD1 3.5Å; Y218-I342 VanDerWaalsContact CE1-CD1 3.5Å; Y218-I342 HydrophobicContact CE1-CG1 3.53Å; Y218-I342 HydrophobicContact CG-CD1 4.03Å; M340-I342 PolarHBondContact O-N 3.47Å; I342-D344 PolarHBondContact O-N 3.48Å
343Q50.1Low56.7Low140 Ų14085.8 Ų85.865%0.65445%0.452SS*.  trans-65.7125.9173.6-69.1-178.24.600108.9R341 L345R341-Q343 PolarHBondContact O-N 3.02Å; Q343-L345 HydrophobicContact CB-CD1 3.88Å; Q343-L345 HydrophobicContact CB-CG 4.27Å; Q343-L345 PolarHBondContact O-N 3.45Å
344D51Low55.6Low91 Ų9188.3 Ų88.349%0.48747%0.47SS..  trans-71.772.2171.4-64.3-70.9000108.9R147 K174 I342 K346R147-D344 IonicContact CZ-OD2 3.94Å; R147-D344 IonicContact NH1-OD1 3.91Å; R147-D344 IonicContact NH1-OD2 3.88Å; R147-D344 PolarHBondContact NH1-OD2 3.11Å; R147-D344 VanDerWaalsContact NH1-OD2 3.07Å; R147-D344 IonicContact NH2-OD2 2.63Å; R147-D344 PolarHBondContact NH2-OD2 2.95Å; K174-D344 IonicContact NZ-OD1 3.82Å; K174-D344 PolarHBondContact NZ-OD1 3.04Å; I342-D344 PolarHBondContact O-N 3.48Å; D344-K346 VanDerWaalsContact C-N 3.28Å; D344-K346 PolarHBondContact O-N 3.48Å
345L44.1Very low55Low125 Ų12589 Ų8965%0.65447%0.47SS*.  trans-7182.3176.9-89.1137.4000109.2Q343 V347Q343-L345 HydrophobicContact CB-CD1 3.88Å; Q343-L345 HydrophobicContact CB-CG 4.27Å; Q343-L345 PolarHBondContact O-N 3.45Å; L345-V347 HydrophobicContact CB-CG2 4.06Å; L345-V347 HydrophobicContact CD2-CG2 3.53Å; L345-V347 HydrophobicContact CG-CG2 4.43Å; L345-V347 PolarHBondContact O-N 3.43Å
346K40.4Very low54.3Low204 Ų20492.2 Ų92.289%0.88749%0.489SS*.  trans-73.378.7158.2-87.4-171.3174.8-177.50108.3D344 S348D344-K346 VanDerWaalsContact C-N 3.28Å; D344-K346 PolarHBondContact O-N 3.48Å; K346-S348 PolarHBondContact O-N 3.22Å
347V42.3Very low54Low94 Ų9495 Ų9557%0.5750%0.504SS*.  trans-85.2103170.4-172.90000107.4L345 L349L345-V347 HydrophobicContact CB-CG2 4.06Å; L345-V347 HydrophobicContact CD2-CG2 3.53Å; L345-V347 HydrophobicContact CG-CG2 4.43Å; L345-V347 PolarHBondContact O-N 3.43Å; V347-L349 PolarHBondContact O-N 2.69Å
348S42.5Very low53.5Low107 Ų10797.9 Ų97.975%0.74852%0.523SS*.  trans-79.1113.2163600000107.7K346 K350K346-S348 PolarHBondContact O-N 3.22Å; S348-K350 PolarHBondContact O-N 3.05Å
349L46.4Very low53.3Low150 Ų15099.8 Ų99.879%0.78553%0.525SS*.PPolyproline II helixtrans-59.1127.2169.5-66.5174.2000108.2V347V347-L349 PolarHBondContact O-N 2.69Å
350K48.9Very low53.2Low149 Ų14996.8 Ų96.865%0.64851%0.509SS*.PPolyproline II helixtrans-62.6145171.2-66.3-176.7179.4-177.50108.4S348 L352 S354 V355S348-K350 PolarHBondContact O-N 3.05Å; K350-L352 PolarHBondContact O-N 2.91Å; K350-S354 WeakPolarHBondContact CB-OG 3.39Å; K350-V355 HydrophobicContact CB-CG2 3.64Å; K350-V355 WeakPolarHBondContact O-CG2 3.36Å
351P55.8Low53.3Low75 Ų7599.9 Ų99.949%0.48752%0.519SS..PPolyproline II helixtrans-50.3140172.6-27.834.6000111.2H353 S354 V355P351-H353 WeakPolarHBondContact CB-CE1 3.42Å; P351-H353 PolarHBondContact O-N 2.92Å; P351-S354 WeakPolarHBondContact CD-OG 3.23Å; P351-S354 WeakPolarHBondContact O-CA 3.24Å; P351-S354 PolarHBondContact O-N 3.36Å; P351-S354 PolarHBondContact O-OG 3.14Å; P351-V355 PolarHBondContact O-N 3.34Å
352L50.4Low53.2Low117 Ų117100.7 Ų100.761%0.61352%0.524SS*.G310 helixtrans-53.2-30.6-170.4-164.969000114K350 S354 L360K350-L352 PolarHBondContact O-N 2.91Å; L352-S354 VanDerWaalsContact C-N 3.29Å; L352-S354 PolarHBondContact O-N 3.1Å; L352-L360 HydrophobicContact CD1-CD1 3.91Å; L352-L360 HydrophobicContact CD1-CD2 3.66Å; L352-L360 HydrophobicContact CD1-CG 4.46Å; L352-L360 HydrophobicContact CG-CD2 4.41Å
353H57.8Low53.6Low163 Ų163107 Ų10776%0.75554%0.544SS*.G310 helixtrans-70.5-21.4177.260.8-100.4000114P351P351-H353 WeakPolarHBondContact CB-CE1 3.42Å; P351-H353 PolarHBondContact O-N 2.92Å
354S50.3Low54.3Low58 Ų58106.7 Ų106.741%0.40654%0.54SS..G310 helixtrans-105.7-1.5-177.768.60000113.5K350 P351 L352K350-S354 WeakPolarHBondContact CB-OG 3.39Å; P351-S354 WeakPolarHBondContact CD-OG 3.23Å; P351-S354 WeakPolarHBondContact O-CA 3.24Å; P351-S354 PolarHBondContact O-N 3.36Å; P351-S354 PolarHBondContact O-OG 3.14Å; L352-S354 VanDerWaalsContact C-N 3.29Å; L352-S354 PolarHBondContact O-N 3.1Å
355V60.8Low54.7Low49 Ų49104.4 Ų104.430%0.29753%0.528SS..  trans-89.1123179.4178.60000109.8K350 P351 N357 L360K350-V355 HydrophobicContact CB-CG2 3.64Å; K350-V355 WeakPolarHBondContact O-CG2 3.36Å; P351-V355 PolarHBondContact O-N 3.34Å; V355-N357 HydrophobicContact CG1-CB 3.97Å; V355-L360 HydrophobicContact CB-CD1 4.35Å; V355-L360 HydrophobicContact CG1-CD1 3.83Å
356N54.2Low55.4Low118 Ų118101.3 Ų101.363%0.63151%0.511SS*.  trans-106.392.5174.4-168.326.7000110.2R361N356-R361 PolarHBondContact ND2-NH2 2.85Å; N356-R361 PolarHBondContact OD1-NE 3.4Å; N356-R361 PolarHBondContact OD1-NH2 3.25Å
357N63Low56.2Low63 Ų6393.8 Ų93.834%0.33749%0.492SS..  trans-127.9133.3-176.4178.4-59.4000110.8V355 I359 L360 R361V355-N357 HydrophobicContact CG1-CB 3.97Å; N357-I359 VanDerWaalsContact C-N 3.29Å; N357-I359 PolarHBondContact O-N 3.33Å; N357-I359 WeakPolarHBondContact OD1-CB 3.22Å; N357-I359 PolarHBondContact OD1-N 3.21Å; N357-L360 HydrophobicContact CB-CB 4.2Å; N357-L360 HydrophobicContact CB-CD1 4.06Å; N357-L360 WeakPolarHBondContact O-CB 3.2Å; N357-L360 PolarHBondContact O-N 2.94Å; N357-L360 VanDerWaalsContact O-N 3.1Å; N357-R361 WeakPolarHBondContact O-CG 3.45Å; N357-R361 PolarHBondContact O-N 3.22Å
358P57.9Low56.5Low65 Ų6595.9 Ų95.942%0.42251%0.505SS..Hα-helixtrans-54.3-36.7-178.4-27.334.7000115R361 K362 L402P358-R361 PolarHBondContact O-N 3.21Å; P358-K362 PolarHBondContact O-N 3.44Å; P358-L402 HydrophobicContact CB-CD2 4.46Å
359I61.8Low56.8Low93 Ų93100 Ų10048%0.47751%0.51SS..Hα-helixtrans-71.2-41.2179-59171.8000110.7N357 R361 K362 R363N357-I359 VanDerWaalsContact C-N 3.29Å; N357-I359 PolarHBondContact O-N 3.33Å; N357-I359 WeakPolarHBondContact OD1-CB 3.22Å; N357-I359 PolarHBondContact OD1-N 3.21Å; I359-R361 VanDerWaalsContact C-N 3.33Å; I359-K362 PolarHBondContact O-N 2.83Å; I359-R363 PolarHBondContact O-N 3.08Å
360L60.9Low56.4Low51 Ų5199 Ų9927%0.26751%0.512SS..Hα-helixtrans-64.3-38.7174.5-91.2157.6000111.5L352 V355 N357 R363 K364L352-L360 HydrophobicContact CD1-CD1 3.91Å; L352-L360 HydrophobicContact CD1-CD2 3.66Å; L352-L360 HydrophobicContact CD1-CG 4.46Å; L352-L360 HydrophobicContact CG-CD2 4.41Å; V355-L360 HydrophobicContact CB-CD1 4.35Å; V355-L360 HydrophobicContact CG1-CD1 3.83Å; N357-L360 HydrophobicContact CB-CB 4.2Å; N357-L360 HydrophobicContact CB-CD1 4.06Å; N357-L360 WeakPolarHBondContact O-CB 3.2Å; N357-L360 PolarHBondContact O-N 2.94Å; N357-L360 VanDerWaalsContact O-N 3.1Å; L360-R363 PolarHBondContact O-N 3.05Å; L360-K364 WeakPolarHBondContact O-CG 3.48Å; L360-K364 PolarHBondContact O-N 2.98Å
361R63.1Low55.9Low92 Ų92100.9 Ų100.935%0.34752%0.52SS..Hα-helixtrans-61-49172.5-69.5175.2177-165.1-11.9111.4N356 N357 P358 I359 R363 K364 L365N356-R361 PolarHBondContact ND2-NH2 2.85Å; N356-R361 PolarHBondContact OD1-NE 3.4Å; N356-R361 PolarHBondContact OD1-NH2 3.25Å; N357-R361 WeakPolarHBondContact O-CG 3.45Å; N357-R361 PolarHBondContact O-N 3.22Å; P358-R361 PolarHBondContact O-N 3.21Å; I359-R361 VanDerWaalsContact C-N 3.33Å; R361-R363 VanDerWaalsContact C-N 3.33Å; R361-R363 PolarHBondContact O-N 3.16Å; R361-K364 PolarHBondContact O-N 3.17Å; R361-L365 WeakPolarHBondContact O-CB 3.43Å; R361-L365 WeakPolarHBondContact O-CG 3.43Å; R361-L365 PolarHBondContact O-N 3.31Å
362K60.1Low54.9Low53 Ų53104.7 Ų104.723%0.2354%0.537CS..Hα-helixtrans-56.5-44.5177.3-176.4165.9178.3174.10112.2P358 I359 L365 L366 I401 L402P358-K362 PolarHBondContact O-N 3.44Å; I359-K362 PolarHBondContact O-N 2.83Å; K362-L365 PolarHBondContact O-N 2.93Å; K362-L366 HydrophobicContact CD-CD1 4.19Å; K362-L366 HydrophobicContact CG-CD1 3.5Å; K362-L366 HydrophobicContact CG-CG 4.25Å; K362-L366 WeakPolarHBondContact O-CB 3.41Å; K362-L366 VanDerWaalsContact O-CG 3.3Å; K362-L366 WeakPolarHBondContact O-CG 3.31Å; K362-L366 PolarHBondContact O-N 2.95Å; K362-I401 HydrophobicContact CB-CD1 4.35Å; K362-I401 HydrophobicContact CB-CG2 4.03Å; K362-L402 HydrophobicContact CB-CD1 4.42Å; K362-L402 HydrophobicContact CD-CD1 3.69Å
363R63.6Low54Low191 Ų191104.9 Ų104.972%0.72155%0.548SS*.Hα-helixtrans-69.1-33.4178.5-74.9-172.6172.7143.7-0.5114.1I359 L360 R361I359-R363 PolarHBondContact O-N 3.08Å; L360-R363 PolarHBondContact O-N 3.05Å; R361-R363 VanDerWaalsContact C-N 3.33Å; R361-R363 PolarHBondContact O-N 3.16Å
364K64.6Low52.7Low133 Ų133103.8 Ų103.858%0.57855%0.552SS**Hα-helixtrans-70-36.4173.3-75.4-176.9178.9-175.40112.2L360 R361L360-K364 WeakPolarHBondContact O-CG 3.48Å; L360-K364 PolarHBondContact O-N 2.98Å; R361-K364 PolarHBondContact O-N 3.17Å
365L59.5Low51.9Low42 Ų42111.4 Ų111.422%0.2257%0.574CS.*Hα-helixtrans-79.4-32.5-177.7-72.1166.1000112.9R361 K362 G367 I397 I401 K460R361-L365 WeakPolarHBondContact O-CB 3.43Å; R361-L365 WeakPolarHBondContact O-CG 3.43Å; R361-L365 PolarHBondContact O-N 3.31Å; K362-L365 PolarHBondContact O-N 2.93Å; L365-G367 VanDerWaalsContact C-N 3.35Å; L365-I397 HydrophobicContact CB-CG2 4.17Å; L365-I401 HydrophobicContact CB-CD1 4.12Å; L365-I401 HydrophobicContact CD1-CD1 3.39Å; L365-I401 HydrophobicContact CD1-CG1 4.12Å; L365-I401 HydrophobicContact CG-CD1 4.37Å; L365-K460 HydrophobicContact CB-CD 4.24Å; L365-K460 HydrophobicContact CD2-CD 3.43Å; L365-K460 VanDerWaalsContact CD2-CD 3.43Å; L365-K460 HydrophobicContact CG-CD 4.42Å; L365-K460 WeakPolarHBondContact O-CD 3.38Å; L365-K460 WeakPolarHBondContact O-CE 3.2Å
366L60.2Low50.5Low60 Ų60116.2 Ų116.231%0.31460%0.596SS.*SBendtrans-81.1-8.2179.7-71.1172.1000114.9K362 R394 I397K362-L366 HydrophobicContact CD-CD1 4.19Å; K362-L366 HydrophobicContact CG-CD1 3.5Å; K362-L366 HydrophobicContact CG-CG 4.25Å; K362-L366 WeakPolarHBondContact O-CB 3.41Å; K362-L366 VanDerWaalsContact O-CG 3.3Å; K362-L366 WeakPolarHBondContact O-CG 3.31Å; K362-L366 PolarHBondContact O-N 2.95Å; L366-R394 HydrophobicContact CD2-CB 4.07Å; L366-R394 HydrophobicContact CD2-CG 4.19Å; L366-I397 HydrophobicContact CD2-CG2 4.47Å
367G55.4Low49.6Very low47 Ų47118.9 Ų118.949%0.48560%0.604SS.*  trans65.4161-17600000113.8L365L365-G367 VanDerWaalsContact C-N 3.35Å
368T50.2Low47.9Very low137 Ų137123.1 Ų123.184%0.8463%0.627SS**PPolyproline II helixtrans-75126.5166.543.10000108.5
369K47.3Very low47.2Very low194 Ų194128.8 Ų128.884%0.84365%0.647SS**PPolyproline II helixtrans-48.4131166.1-72.3-171.7175.4-169.40108.4K371K369-K371 PolarHBondContact O-N 3.27Å; K369-K371 VanDerWaalsContact O-N 3.11Å
370P38.1Very low45.9Very low129 Ų129133.4 Ų133.484%0.83867%0.667SS**PPolyproline II helixtrans-59.1119.1163.4-14.727.7000107.2
371K38.9Very low45Very low189 Ų189139.1 Ų139.182%0.82270%0.698SS**  trans-85.4114.3159.4-82-176.3172.6-174.90105.5K369K369-K371 PolarHBondContact O-N 3.27Å; K369-K371 VanDerWaalsContact O-N 3.11Å
372D35.7Very low44Very low155 Ų155138.4 Ų138.483%0.82972%0.72SS**  trans158.997.8130.7-77.3-16.5000110.4
373S30.8Very low43.3Very low121 Ų121139.8 Ų139.885%0.84674%0.741SS**  trans-167113.8143.547.50000112.1
374V31.2Very low42.7Very low140 Ų140138.6 Ų138.685%0.84874%0.743SS**  trans-16.6139.1156.2-1770000116.9
375Y33.1Very low42.1Very low217 Ų217138 Ų13885%0.85175%0.746SS**  trans-44.9130.4164.5-85.6-95.4000113.3
376I31.7Very low42Very low151 Ų151137.5 Ų137.577%0.77475%0.747SS**  -150.8130.3129.7-62.2-166.5000107.6
377H34.9Very low42.3Very low173 Ų173139.7 Ų139.780%0.80176%0.758SS**  trans-70.8123.6162.9-108-69.1000108.3
378D28Very low43.3Very low152 Ų152139.5 Ų139.581%0.81375%0.748SS**  trans-143.4131.9153.8-103.5-31000110.6E380D378-E380 PolarHBondContact O-N 3.4Å
379H41.7Very low44.6Very low184 Ų184133.4 Ų133.485%0.85271%0.712SS**  trans-82.4102.9176-114.2-76.3000107.5
380E35.8Very low46.1Very low191 Ų191124.9 Ų124.989%0.89368%0.675SS**  trans-165.6121.7153.3-110.3167.9-157.800112.3D378D378-E380 PolarHBondContact O-N 3.4Å
381N41.9Very low48.1Very low170 Ų170123.6 Ų123.691%0.90966%0.658SS**SBendtrans-16.4133174-66.7-37.5000120.2
382G41.1Very low50.3Low78 Ų78116.6 Ų116.680%0.80463%0.627SS**SBendtrans142.9-24.5151.100000116.9
383A46.4Very low52.7Low81 Ų81109.2 Ų109.267%0.66959%0.588SS**SBendtrans-103.1-8.4-168.400000115.8
384E50.3Low55.1Low166 Ų166108 Ų10878%0.77657%0.565SS**Hα-helixtrans-70.2-40-178.2-75.3-173.5152.600112.7S386 N387 V388E384-S386 PolarHBondContact O-N 2.99Å; E384-N387 PolarHBondContact O-N 2.85Å; E384-V388 WeakPolarHBondContact O-CG2 3.27Å; E384-V388 PolarHBondContact O-N 3.37Å
385D52.3Low57.5Low121 Ų121104.3 Ų104.365%0.64754%0.54SS*.Hα-helixtrans-67.1-36.5-174.6-85.7-22.7000113.4A389D385-A389 VanDerWaalsContact O-CB 3.28Å; D385-A389 WeakPolarHBondContact O-CB 3.49Å; D385-A389 PolarHBondContact O-N 2.98Å
386S57.6Low60Low32 Ų3294 Ų9422%0.22450%0.5CS..Hα-helixtrans-69.2-37177.5-176.70000111.6E384 A389 L390 H470E384-S386 PolarHBondContact O-N 2.99Å; S386-A389 PolarHBondContact O-N 2.9Å; S386-L390 WeakPolarHBondContact O-CG 3.22Å; S386-L390 PolarHBondContact O-N 3.49Å; S386-H470 PolarHBondContact OG-CD2 2.88Å; S386-H470 PolarHBondContact OG-NE2 3.11Å
387N66.4Low62.4Low105 Ų10586.8 Ų86.856%0.56146%0.463SS*.Hα-helixtrans-70.1-39.7178.3-153.53.2000111.4E384 E391E384-N387 PolarHBondContact O-N 2.85Å; N387-E391 WeakPolarHBondContact O-CB 3.37Å; N387-E391 PolarHBondContact O-N 3.42Å
388V75.7Confident64.5Low44 Ų4479.4 Ų79.427%0.26743%0.432SS..Hα-helixtrans-65.4-41.6172.9175.90000110.9E384 L390 E391 K392 Y425E384-V388 WeakPolarHBondContact O-CG2 3.27Å; E384-V388 PolarHBondContact O-N 3.37Å; V388-L390 PolarHBondContact O-N 3.41Å; V388-E391 PolarHBondContact O-N 3.34Å; V388-K392 HydrophobicContact CG1-CG 4.36Å; V388-K392 WeakPolarHBondContact O-CG 3.45Å; V388-K392 PolarHBondContact O-N 3.18Å; V388-Y425 HydrophobicContact CG1-CD1 4.02Å; V388-Y425 HydrophobicContact CG1-CD2 4.42Å; V388-Y425 HydrophobicContact CG1-CE1 3.79Å; V388-Y425 HydrophobicContact CG1-CE2 4.24Å; V388-Y425 HydrophobicContact CG1-CG 4.34Å
389A77.3Confident67.1Low9 Ų972.9 Ų72.97%0.07440%0.396CS..Hα-helixtrans-59.1-44.8177.700000112.4D385 S386 L393 N426D385-A389 VanDerWaalsContact O-CB 3.28Å; D385-A389 WeakPolarHBondContact O-CB 3.49Å; D385-A389 PolarHBondContact O-N 2.98Å; S386-A389 PolarHBondContact O-N 2.9Å; A389-L393 WeakPolarHBondContact O-CG 3.47Å; A389-L393 PolarHBondContact O-N 3.47Å; A389-N426 PolarHBondContact O-ND2 3.25Å
390L79.5Confident69Low14 Ų1464.5 Ų64.57%0.07336%0.358CS..Hα-helixtrans-70.1-37.1176.5-67.1174.8000112.4S386 V388 L393 R394 I463 Q466 T467S386-L390 WeakPolarHBondContact O-CG 3.22Å; S386-L390 PolarHBondContact O-N 3.49Å; V388-L390 PolarHBondContact O-N 3.41Å; L390-L393 PolarHBondContact O-N 3.27Å; L390-R394 WeakPolarHBondContact O-CG 3.47Å; L390-R394 PolarHBondContact O-N 3.33Å; L390-I463 HydrophobicContact CD2-CB 4.45Å; L390-I463 HydrophobicContact CD2-CG1 4.36Å; L390-I463 HydrophobicContact CD2-CG2 4.21Å; L390-Q466 HydrophobicContact CD2-CB 3.96Å; L390-T467 HydrophobicContact CD1-CG2 3.88Å; L390-T467 HydrophobicContact CD2-CG2 4.43Å
391E80.8Confident70.8Confident102 Ų10256.3 Ų56.348%0.47732%0.32SS..Hα-helixtrans-60.6-46.1175.3-173.5173.3-16200111.3N387 V388 L393 R394 D395N387-E391 WeakPolarHBondContact O-CB 3.37Å; N387-E391 PolarHBondContact O-N 3.42Å; V388-E391 PolarHBondContact O-N 3.34Å; E391-L393 VanDerWaalsContact C-N 3.32Å; E391-L393 PolarHBondContact O-N 2.96Å; E391-R394 WeakPolarHBondContact O-CA 3.5Å; E391-R394 WeakPolarHBondContact O-CB 3.37Å; E391-R394 PolarHBondContact O-N 3.16Å; E391-D395 PolarHBondContact O-N 3.18Å
392K85.2Confident72.2Confident43 Ų4351.4 Ų51.419%0.18729%0.294CS..Hα-helixtrans-64.5-34.1178.2-62.6-57.4-179.6175.60113.2V388 D395 V396 E421 A422 Y425V388-K392 HydrophobicContact CG1-CG 4.36Å; V388-K392 WeakPolarHBondContact O-CG 3.45Å; V388-K392 PolarHBondContact O-N 3.18Å; K392-D395 PolarHBondContact O-N 3.26Å; K392-V396 PolarHBondContact O-N 3.16Å; K392-E421 HydrophobicContact CD-CB 4.24Å; K392-E421 IonicContact NZ-OE2 2.75Å; K392-E421 PolarHBondContact NZ-OE2 3.43Å; K392-A422 HydrophobicContact CB-CB 4.04Å; K392-Y425 HydrophobicContact CG-CD2 3.9Å; K392-Y425 HydrophobicContact CG-CE2 4.19Å
393L84.1Confident73.7Confident0 Ų049.9 Ų49.90%027%0.27CS..Hα-helixtrans-67.3-36.2171.6-68171.9000112.1A389 L390 E391 D395 V396 I397 A422 N426 L432 V459 V462 I463A389-L393 WeakPolarHBondContact O-CG 3.47Å; A389-L393 PolarHBondContact O-N 3.47Å; L390-L393 PolarHBondContact O-N 3.27Å; E391-L393 VanDerWaalsContact C-N 3.32Å; E391-L393 PolarHBondContact O-N 2.96Å; L393-D395 VanDerWaalsContact C-N 3.31Å; L393-D395 PolarHBondContact O-N 3.28Å; L393-V396 WeakPolarHBondContact O-CB 3.28Å; L393-V396 PolarHBondContact O-N 2.89Å; L393-I397 PolarHBondContact O-N 3.17Å; L393-A422 HydrophobicContact CD2-CB 4.09Å; L393-N426 VanDerWaalsContact CD1-OD1 3.31Å; L393-N426 WeakPolarHBondContact CD1-OD1 3.35Å; L393-N426 HydrophobicContact CD2-CB 4.49Å; L393-L432 HydrophobicContact CD2-CD1 4.11Å; L393-L432 HydrophobicContact CD2-CD2 3.98Å; L393-V459 HydrophobicContact CB-CG1 3.9Å; L393-V459 HydrophobicContact CD2-CG1 3.92Å; L393-V459 HydrophobicContact CG-CG1 4.46Å; L393-V459 WeakPolarHBondContact O-CG1 3.45Å; L393-V462 HydrophobicContact CD1-CG1 3.82Å; L393-I463 HydrophobicContact CB-CD1 3.75Å; L393-I463 HydrophobicContact CB-CG1 3.67Å; L393-I463 HydrophobicContact CD1-CG1 3.89Å; L393-I463 HydrophobicContact CG-CG1 4.45Å
394R82.1Confident74.4Confident95 Ų9553 Ų5336%0.35827%0.27SS..Hα-helixtrans-66.5-33.5174.5-70.1170.1177.6157.72.3112.1L366 L390 E391 I397 A398 I463L366-R394 HydrophobicContact CD2-CB 4.07Å; L366-R394 HydrophobicContact CD2-CG 4.19Å; L390-R394 WeakPolarHBondContact O-CG 3.47Å; L390-R394 PolarHBondContact O-N 3.33Å; E391-R394 WeakPolarHBondContact O-CA 3.5Å; E391-R394 WeakPolarHBondContact O-CB 3.37Å; E391-R394 PolarHBondContact O-N 3.16Å; R394-I397 PolarHBondContact O-N 2.9Å; R394-A398 WeakPolarHBondContact O-CB 3.49Å; R394-A398 PolarHBondContact O-N 2.98Å; R394-I463 HydrophobicContact CG-CD1 3.8Å
395D82.7Confident74.8Confident62 Ų6247 Ų4733%0.33225%0.25SS..Hα-helixtrans-64.3-40.4174.1-70.5-22.6000111.6E391 K392 L393 I397 A398 Q399 V418E391-D395 PolarHBondContact O-N 3.18Å; K392-D395 PolarHBondContact O-N 3.26Å; L393-D395 VanDerWaalsContact C-N 3.31Å; L393-D395 PolarHBondContact O-N 3.28Å; D395-I397 PolarHBondContact O-N 3.03Å; D395-A398 WeakPolarHBondContact O-CB 3.45Å; D395-A398 PolarHBondContact O-N 3.46Å; D395-Q399 PolarHBondContact O-N 3.17Å; D395-V418 VanDerWaalsContact C-CG1 3.47Å; D395-V418 HydrophobicContact CB-CG1 3.72Å
396V84.6Confident75.1Confident0 Ų043 Ų430%024%0.237CC..Hα-helixtrans-59.5-47.3173.4176.60000110.6K392 L393 A398 Q399 C400 V418 M419 A422 L455 V459K392-V396 PolarHBondContact O-N 3.16Å; L393-V396 WeakPolarHBondContact O-CB 3.28Å; L393-V396 PolarHBondContact O-N 2.89Å; V396-A398 VanDerWaalsContact C-N 3.29Å; V396-A398 PolarHBondContact O-N 2.9Å; V396-Q399 PolarHBondContact O-N 3.22Å; V396-C400 WeakPolarHBondContact O-CB 3.2Å; V396-C400 PolarHBondContact O-N 3.33Å; V396-C400 PolarHBondContact O-SG 3.39Å; V396-C400 VanDerWaalsContact O-SG 3.41Å; V396-V418 HydrophobicContact CB-CG1 4.39Å; V396-V418 HydrophobicContact CG2-CG1 3.82Å; V396-M419 HydrophobicContact CB-SD 4.46Å; V396-M419 HydrophobicContact CG1-SD 3.75Å; V396-M419 HydrophobicContact CG2-CB 4.47Å; V396-M419 HydrophobicContact CG2-SD 3.84Å; V396-A422 HydrophobicContact CG2-CB 3.54Å; V396-L455 HydrophobicContact CG1-CD2 4.38Å; V396-V459 HydrophobicContact CG1-CG2 4.25Å
397I82.4Confident74.5Confident1 Ų152.3 Ų52.31%0.00527%0.274CS..Hα-helixtrans-58.7-43.6175.8-66.7175.4000110.5L365 L366 L393 R394 D395 C400 I401 A456 V459 K460 I463L365-I397 HydrophobicContact CB-CG2 4.17Å; L366-I397 HydrophobicContact CD2-CG2 4.47Å; L393-I397 PolarHBondContact O-N 3.17Å; R394-I397 PolarHBondContact O-N 2.9Å; D395-I397 PolarHBondContact O-N 3.03Å; I397-C400 PolarHBondContact O-N 3.41Å; I397-I401 HydrophobicContact CG2-CD1 3.53Å; I397-I401 HydrophobicContact CG2-CG1 4.48Å; I397-I401 WeakPolarHBondContact O-CD1 3.05Å; I397-I401 VanDerWaalsContact O-CG1 3.22Å; I397-I401 WeakPolarHBondContact O-CG1 3.4Å; I397-I401 PolarHBondContact O-N 3.18Å; I397-I401 VanDerWaalsContact O-N 3.16Å; I397-A456 HydrophobicContact CG2-CB 4.41Å; I397-V459 HydrophobicContact CD1-CB 4.46Å; I397-V459 HydrophobicContact CD1-CG1 4.04Å; I397-V459 HydrophobicContact CG1-CB 4.1Å; I397-V459 HydrophobicContact CG1-CG1 3.77Å; I397-K460 HydrophobicContact CD1-CB 3.97Å; I397-I463 HydrophobicContact CD1-CD1 3.61Å
398A78.9Confident74.1Confident18 Ų1851.4 Ų51.415%0.14929%0.289CS..Hα-helixtrans-62-45.1178.900000112R394 D395 V396 I401 L402R394-A398 WeakPolarHBondContact O-CB 3.49Å; R394-A398 PolarHBondContact O-N 2.98Å; D395-A398 WeakPolarHBondContact O-CB 3.45Å; D395-A398 PolarHBondContact O-N 3.46Å; V396-A398 VanDerWaalsContact C-N 3.29Å; V396-A398 PolarHBondContact O-N 2.9Å; A398-I401 PolarHBondContact O-N 3.04Å; A398-L402 CarbonylContact O-C 3.5Å; A398-L402 PolarHBondContact O-N 3.03Å
399Q82.3Confident73.4Confident14 Ų1454.6 Ų54.67%0.06530%0.301CS..Hα-helixtrans-68.1-34179.6-172.660.911.800112.4D395 V396 P403 L415 V418D395-Q399 PolarHBondContact O-N 3.17Å; V396-Q399 PolarHBondContact O-N 3.22Å; Q399-P403 WeakPolarHBondContact O-CA 3.42Å; Q399-L415 HydrophobicContact CB-CD1 4.4Å; Q399-L415 HydrophobicContact CG-CB 4.34Å; Q399-L415 HydrophobicContact CG-CD1 4.15Å; Q399-V418 HydrophobicContact CG-CG2 4.45Å
400C81.1Confident73.4Confident8 Ų857.9 Ų57.95%0.05432%0.318CS..Hα-helixtrans-67.1-34.4174.4-78.70000113.6V396 I397 R452 A456V396-C400 WeakPolarHBondContact O-CB 3.2Å; V396-C400 PolarHBondContact O-N 3.33Å; V396-C400 PolarHBondContact O-SG 3.39Å; V396-C400 VanDerWaalsContact O-SG 3.41Å; I397-C400 PolarHBondContact O-N 3.41Å; C400-R452 HydrophobicContact CB-CB 3.97Å; C400-R452 VanDerWaalsContact CB-O 3.28Å; C400-R452 WeakPolarHBondContact CB-O 3.34Å; C400-R452 PolarHBondContact SG-O 2.97Å; C400-A456 HydrophobicContact CB-CB 3.85Å
401I74.6Confident73.2Confident19 Ų1961.2 Ų61.210%0.09733%0.332CS..Hα-helixtrans-91.8-39.9-174.8-60.4164.1000112.2K362 L365 I397 A398 A456K362-I401 HydrophobicContact CB-CD1 4.35Å; K362-I401 HydrophobicContact CB-CG2 4.03Å; L365-I401 HydrophobicContact CB-CD1 4.12Å; L365-I401 HydrophobicContact CD1-CD1 3.39Å; L365-I401 HydrophobicContact CD1-CG1 4.12Å; L365-I401 HydrophobicContact CG-CD1 4.37Å; I397-I401 HydrophobicContact CG2-CD1 3.53Å; I397-I401 HydrophobicContact CG2-CG1 4.48Å; I397-I401 WeakPolarHBondContact O-CD1 3.05Å; I397-I401 VanDerWaalsContact O-CG1 3.22Å; I397-I401 WeakPolarHBondContact O-CG1 3.4Å; I397-I401 PolarHBondContact O-N 3.18Å; I397-I401 VanDerWaalsContact O-N 3.16Å; A398-I401 PolarHBondContact O-N 3.04Å; I401-A456 HydrophobicContact CG1-CB 4.49Å
402L70.9Confident73.1Confident68 Ų6859.6 Ų59.636%0.35633%0.327SS..SBendtrans-138.281.4-176.5-84.7160.7000108.2P358 K362 A398 Q404P358-L402 HydrophobicContact CB-CD2 4.46Å; K362-L402 HydrophobicContact CB-CD1 4.42Å; K362-L402 HydrophobicContact CD-CD1 3.69Å; A398-L402 CarbonylContact O-C 3.5Å; A398-L402 PolarHBondContact O-N 3.03Å; L402-Q404 PolarHBondContact O-N 3.31Å
403P72.3Confident72.9Confident46 Ų4663.1 Ų63.130%0.29934%0.344SS..  trans-58.7123.2-179.2-18.930.3000109.8Q399 E411 R452Q399-P403 WeakPolarHBondContact O-CA 3.42Å; P403-E411 HydrophobicContact CB-CB 4.44Å; P403-E411 HydrophobicContact CB-CG 4.07Å; P403-R452 VanDerWaalsContact CG-NH1 3.26Å
404Q61.9Low72.9Confident145 Ų14566.1 Ų66.168%0.67836%0.358SS*.  trans-100.293.7170.1-62.6-161.310.500107.8L402L402-Q404 PolarHBondContact O-N 3.31Å
405A59.1Low73Confident42 Ų4261.7 Ų61.735%0.34734%0.341SS..  trans-99.7129.7167.900000108.9E409 E411A405-E409 HydrophobicContact CB-CB 4.24Å; A405-E411 HydrophobicContact CB-CG 4.04Å
406G58.1Low73.2Confident37 Ų3760.5 Ų60.538%0.38134%0.335SS..  trans-58.5157.7163.700000110.2G408 E409G406-G408 PolarHBondContact O-N 3.29Å; G406-E409 PolarHBondContact N-OE2 3.49Å; G406-E409 PolarHBondContact O-N 3.06Å
407K45.4Very low73.3Confident227 Ų22765 Ų6599%0.98736%0.356SS*.THydrogen-bonded Turntrans-56.3105.9176.2-81.8-176.3177.3178.40109.8
408G56.6Low73.5Confident86 Ų8666 Ų6689%0.88736%0.362SS*.THydrogen-bonded Turntrans107.6-0.5177.700000115.9G406G406-G408 PolarHBondContact O-N 3.29Å
409E62.7Low74Confident111 Ų11165.1 Ų65.152%0.51935%0.354SS..  trans-90.4143.2177.4-68175.617000112.2A405 G406A405-E409 HydrophobicContact CB-CB 4.24Å; G406-E409 PolarHBondContact N-OE2 3.49Å; G406-E409 PolarHBondContact O-N 3.06Å
410N75.4Confident74.2Confident78 Ų7867.9 Ų67.942%0.41737%0.367SS..  trans-79.4121.8175.6-175.7-5000110.1D412 E413 K414N410-D412 PolarHBondContact O-N 2.94Å; N410-D412 PolarHBondContact OD1-N 3.37Å; N410-E413 HydrophobicContact CB-CB 4.14Å; N410-E413 HydrophobicContact CB-CG 3.96Å; N410-E413 WeakPolarHBondContact O-CB 3.34Å; N410-E413 PolarHBondContact O-N 2.91Å; N410-E413 VanDerWaalsContact O-N 3.1Å; N410-K414 PolarHBondContact O-N 3.33Å
411E76.3Confident74.4Confident83 Ų8371.5 Ų71.539%0.38838%0.383SS..Hα-helixtrans-60-31-177.6-64.1-176.5-176.900113.5P403 A405 K414 L415 R452P403-E411 HydrophobicContact CB-CB 4.44Å; P403-E411 HydrophobicContact CB-CG 4.07Å; A405-E411 HydrophobicContact CB-CG 4.04Å; E411-K414 PolarHBondContact O-N 3.03Å; E411-L415 WeakPolarHBondContact O-CB 3.46Å; E411-L415 PolarHBondContact O-N 3.35Å; E411-R452 VanDerWaalsContact CB-NH2 3.28Å; E411-R452 IonicContact OE2-CZ 2.68Å; E411-R452 IonicContact OE2-NH1 3.72Å; E411-R452 PolarHBondContact OE2-NH1 2.99Å; E411-R452 IonicContact OE2-NH2 2.77Å; E411-R452 PolarHBondContact OE2-NH2 2.66Å
412D79.6Confident75Confident68 Ų6870.6 Ų70.636%0.36438%0.379SS..Hα-helixtrans-73.1-35.1177.9-71.3-26.9000111.5N410 K414 L415 N416 R452N410-D412 PolarHBondContact O-N 2.94Å; N410-D412 PolarHBondContact OD1-N 3.37Å; D412-K414 VanDerWaalsContact C-N 3.34Å; D412-L415 PolarHBondContact O-N 3.17Å; D412-N416 VanDerWaalsContact O-CG 3.29Å; D412-N416 PolarHBondContact O-N 3.4Å; D412-N416 PolarHBondContact O-ND2 2.91Å; D412-N416 VanDerWaalsContact O-ND2 3.13Å; D412-R452 IonicContact OD1-CZ 2.59Å; D412-R452 IonicContact OD1-NE 3.13Å; D412-R452 IonicContact OD1-NH2 2.87Å; D412-R452 PolarHBondContact OD1-NH2 3.13Å
413E80.9Confident75.7Confident117 Ų11770.2 Ų70.255%0.54737%0.373SS..Hα-helixtrans-64.3-43.2171.5-72.9173.4-175.700110.3N410 L415 N416 E417N410-E413 HydrophobicContact CB-CB 4.14Å; N410-E413 HydrophobicContact CB-CG 3.96Å; N410-E413 WeakPolarHBondContact O-CB 3.34Å; N410-E413 PolarHBondContact O-N 2.91Å; N410-E413 VanDerWaalsContact O-N 3.1Å; E413-L415 VanDerWaalsContact C-N 3.33Å; E413-L415 PolarHBondContact O-N 3.4Å; E413-N416 WeakPolarHBondContact O-CB 3.48Å; E413-N416 PolarHBondContact O-N 2.78Å; E413-N416 VanDerWaalsContact O-N 3.15Å; E413-E417 PolarHBondContact O-N 3.33Å
414K82.5Confident76.3Confident64 Ų6474.3 Ų74.328%0.27839%0.386SS..Hα-helixtrans-65.6-37.2178.1-165.956.9170.9-176.80112.7N410 E411 D412 N416 E417 V418N410-K414 PolarHBondContact O-N 3.33Å; E411-K414 PolarHBondContact O-N 3.03Å; D412-K414 VanDerWaalsContact C-N 3.34Å; K414-N416 VanDerWaalsContact C-N 3.35Å; K414-E417 WeakPolarHBondContact CD-OE2 3.49Å; K414-E417 IonicContact NZ-OE2 3.53Å; K414-E417 PolarHBondContact NZ-OE2 3.06Å; K414-E417 PolarHBondContact O-N 3.38Å; K414-V418 VanDerWaalsContact O-CG2 3.29Å; K414-V418 WeakPolarHBondContact O-CG2 3.35Å; K414-V418 PolarHBondContact O-N 3.16Å; K414-V418 VanDerWaalsContact O-N 3.09Å
415L85.1Confident77.3Confident1 Ų172.9 Ų72.91%0.00538%0.375CS..Hα-helixtrans-64.2-40.6173.2-179.460.5000111.6Q399 E411 D412 E413 V418 M419 F446 V450 R452Q399-L415 HydrophobicContact CB-CD1 4.4Å; Q399-L415 HydrophobicContact CG-CB 4.34Å; Q399-L415 HydrophobicContact CG-CD1 4.15Å; E411-L415 WeakPolarHBondContact O-CB 3.46Å; E411-L415 PolarHBondContact O-N 3.35Å; D412-L415 PolarHBondContact O-N 3.17Å; E413-L415 VanDerWaalsContact C-N 3.33Å; E413-L415 PolarHBondContact O-N 3.4Å; L415-V418 PolarHBondContact O-N 3.07Å; L415-M419 VanDerWaalsContact O-CB 3.26Å; L415-M419 WeakPolarHBondContact O-CB 3.28Å; L415-M419 PolarHBondContact O-N 3.37Å; L415-F446 HydrophobicContact CD2-CE2 4.48Å; L415-F446 HydrophobicContact CG-CE2 4.24Å; L415-V450 HydrophobicContact CD2-CB 4.42Å; L415-V450 HydrophobicContact CD2-CG1 4.4Å; L415-R452 HydrophobicContact CD2-CG 3.95Å
416N87.7Confident78.4Confident38 Ų3871.1 Ų71.120%0.20336%0.36CS..Hα-helixtrans-61.3-44.6174.9-74.4-38.3000111.8D412 E413 K414 M419 Q420 G445 F446D412-N416 VanDerWaalsContact O-CG 3.29Å; D412-N416 PolarHBondContact O-N 3.4Å; D412-N416 PolarHBondContact O-ND2 2.91Å; D412-N416 VanDerWaalsContact O-ND2 3.13Å; E413-N416 WeakPolarHBondContact O-CB 3.48Å; E413-N416 PolarHBondContact O-N 2.78Å; E413-N416 VanDerWaalsContact O-N 3.15Å; K414-N416 VanDerWaalsContact C-N 3.35Å; N416-M419 PolarHBondContact O-N 2.87Å; N416-Q420 VanDerWaalsContact O-CB 3.25Å; N416-Q420 WeakPolarHBondContact O-CB 3.43Å; N416-Q420 PolarHBondContact O-N 3.09Å; N416-G445 VanDerWaalsContact OD1-CA 3.27Å; N416-G445 WeakPolarHBondContact OD1-CA 3.34Å; N416-F446 WeakPolarHBondContact OD1-CD2 3.31Å; N416-F446 PolarHBondContact OD1-N 3.03Å
417E85.7Confident79.5Confident95 Ų9576.5 Ų76.544%0.44437%0.368SS..Hα-helixtrans-58.4-51.8176.5-72.1178.7178.900111.9E413 K414 M419 Q420 E421E413-E417 PolarHBondContact O-N 3.33Å; K414-E417 WeakPolarHBondContact CD-OE2 3.49Å; K414-E417 IonicContact NZ-OE2 3.53Å; K414-E417 PolarHBondContact NZ-OE2 3.06Å; K414-E417 PolarHBondContact O-N 3.38Å; E417-M419 VanDerWaalsContact C-N 3.33Å; E417-M419 PolarHBondContact O-N 3.16Å; E417-Q420 WeakPolarHBondContact O-CB 3.07Å; E417-Q420 PolarHBondContact O-N 3.27Å; E417-E421 PolarHBondContact O-N 2.85Å
418V87.3Confident81.1Confident21 Ų2171.8 Ų71.813%0.12735%0.35CS..Hα-helixtrans-65-39.5-177.6177.90000110.8D395 V396 Q399 K414 L415 Q420 E421 A422D395-V418 VanDerWaalsContact C-CG1 3.47Å; D395-V418 HydrophobicContact CB-CG1 3.72Å; V396-V418 HydrophobicContact CB-CG1 4.39Å; V396-V418 HydrophobicContact CG2-CG1 3.82Å; Q399-V418 HydrophobicContact CG-CG2 4.45Å; K414-V418 VanDerWaalsContact O-CG2 3.29Å; K414-V418 WeakPolarHBondContact O-CG2 3.35Å; K414-V418 PolarHBondContact O-N 3.16Å; K414-V418 VanDerWaalsContact O-N 3.09Å; L415-V418 PolarHBondContact O-N 3.07Å; V418-Q420 VanDerWaalsContact C-N 3.35Å; V418-E421 PolarHBondContact O-N 2.94Å; V418-A422 PolarHBondContact O-N 3.25Å
419M89Confident82.2Confident0 Ų068.7 Ų68.70%031%0.314CS..Hα-helixtrans-67.7-35.4175.3-169.769.4-130.900112.2V396 L415 N416 E417 A422 W423 L432 L436 W441 F446V396-M419 HydrophobicContact CB-SD 4.46Å; V396-M419 HydrophobicContact CG1-SD 3.75Å; V396-M419 HydrophobicContact CG2-CB 4.47Å; V396-M419 HydrophobicContact CG2-SD 3.84Å; L415-M419 VanDerWaalsContact O-CB 3.26Å; L415-M419 WeakPolarHBondContact O-CB 3.28Å; L415-M419 PolarHBondContact O-N 3.37Å; N416-M419 PolarHBondContact O-N 2.87Å; E417-M419 VanDerWaalsContact C-N 3.33Å; E417-M419 PolarHBondContact O-N 3.16Å; M419-A422 HydrophobicContact CE-CB 4.25Å; M419-A422 PolarHBondContact O-N 3.22Å; M419-W423 VanDerWaalsContact O-CB 3.3Å; M419-W423 WeakPolarHBondContact O-CB 3.31Å; M419-W423 PolarHBondContact O-N 3.37Å; M419-L432 HydrophobicContact CE-CD1 4.07Å; M419-L432 HydrophobicContact CE-CD2 4.49Å; M419-L436 HydrophobicContact CE-CD1 3.35Å; M419-L436 HydrophobicContact CE-CD2 3.71Å; M419-L436 HydrophobicContact CE-CG 3.98Å; M419-L436 HydrophobicContact CG-CD2 4.31Å; M419-L436 HydrophobicContact SD-CD1 4.45Å; M419-L436 HydrophobicContact SD-CD2 3.9Å; M419-W441 HydrophobicContact CB-CH2 3.73Å; M419-W441 HydrophobicContact CB-CZ2 4.42Å; M419-W441 HydrophobicContact CB-CZ3 3.81Å; M419-W441 HydrophobicContact CG-CD2 4.34Å; M419-W441 HydrophobicContact CG-CE3 4.03Å; M419-W441 HydrophobicContact CG-CH2 3.74Å; M419-W441 HydrophobicContact CG-CZ2 4.05Å; M419-W441 HydrophobicContact CG-CZ3 3.71Å; M419-F446 HydrophobicContact CB-CE2 3.94Å; M419-F446 HydrophobicContact CB-CZ 4.25Å; M419-F446 HydrophobicContact CG-CE2 3.84Å; M419-F446 HydrophobicContact CG-CZ 3.63Å; M419-F446 HydrophobicContact SD-CZ 4.17Å
420Q86.6Confident83.1Confident71 Ų7170.1 Ų70.133%0.33232%0.319SS..Hα-helixtrans-66.2-39.5176.6-168.3-178.328.400111.4N416 E417 V418 W423 K424 W441N416-Q420 VanDerWaalsContact O-CB 3.25Å; N416-Q420 WeakPolarHBondContact O-CB 3.43Å; N416-Q420 PolarHBondContact O-N 3.09Å; E417-Q420 WeakPolarHBondContact O-CB 3.07Å; E417-Q420 PolarHBondContact O-N 3.27Å; V418-Q420 VanDerWaalsContact C-N 3.35Å; Q420-W423 PolarHBondContact O-N 2.68Å; Q420-K424 WeakPolarHBondContact O-CG 3.11Å; Q420-K424 PolarHBondContact O-N 3.25Å; Q420-W441 HydrophobicContact CB-CH2 4.19Å; Q420-W441 HydrophobicContact CB-CZ2 4.35Å
421E85.7Confident83.4Confident85 Ų8569 Ų6940%0.39731%0.313SS..Hα-helixtrans-62.1-49.6171.5-68.6-161.1159.500111.2K392 E417 V418 W423 K424 Y425K392-E421 HydrophobicContact CD-CB 4.24Å; K392-E421 IonicContact NZ-OE2 2.75Å; K392-E421 PolarHBondContact NZ-OE2 3.43Å; E417-E421 PolarHBondContact O-N 2.85Å; V418-E421 PolarHBondContact O-N 2.94Å; E421-W423 VanDerWaalsContact C-N 3.29Å; E421-W423 PolarHBondContact O-N 3.21Å; E421-K424 WeakPolarHBondContact O-CB 3.39Å; E421-K424 PolarHBondContact O-N 3.11Å; E421-Y425 VanDerWaalsContact O-CD2 3.24Å; E421-Y425 WeakPolarHBondContact O-CD2 3.48Å
422A87Confident83.7Confident0 Ų065 Ų650%029%0.294CS..Hα-helixtrans-58.9-39.9177.800000112.8K392 L393 V396 V418 M419 K424 Y425 N426K392-A422 HydrophobicContact CB-CB 4.04Å; L393-A422 HydrophobicContact CD2-CB 4.09Å; V396-A422 HydrophobicContact CG2-CB 3.54Å; V418-A422 PolarHBondContact O-N 3.25Å; M419-A422 HydrophobicContact CE-CB 4.25Å; M419-A422 PolarHBondContact O-N 3.22Å; A422-K424 PolarHBondContact O-N 2.95Å; A422-Y425 PolarHBondContact O-N 2.78Å; A422-N426 WeakPolarHBondContact O-CB 3.23Å; A422-N426 PolarHBondContact O-N 3.21Å; A422-N426 VanDerWaalsContact O-N 3.09Å; A422-N426 PolarHBondContact O-ND2 3.37Å
423W85.9Confident83.9Confident59 Ų5966.3 Ų66.322%0.22329%0.294CS..Hα-helixtrans-63.3-37.7178.1-177.7-107.6000113.1M419 Q420 E421 Y425 N426 R427 L432 R433 L436 W441M419-W423 VanDerWaalsContact O-CB 3.3Å; M419-W423 WeakPolarHBondContact O-CB 3.31Å; M419-W423 PolarHBondContact O-N 3.37Å; Q420-W423 PolarHBondContact O-N 2.68Å; E421-W423 VanDerWaalsContact C-N 3.29Å; E421-W423 PolarHBondContact O-N 3.21Å; W423-Y425 VanDerWaalsContact C-N 3.29Å; W423-Y425 PolarHBondContact O-N 3.27Å; W423-N426 PolarHBondContact O-N 2.89Å; W423-R427 WeakPolarHBondContact O-CB 3.35Å; W423-R427 PolarHBondContact O-N 2.96Å; W423-L432 HydrophobicContact CE3-CD2 4.19Å; W423-L432 HydrophobicContact CE3-CG 4.4Å; W423-L432 HydrophobicContact CZ3-CG 4.38Å; W423-R433 HydrophobicContact CH2-CB 4.12Å; W423-R433 HydrophobicContact CH2-CG 3.56Å; W423-R433 HydrophobicContact CZ3-CB 4.41Å; W423-R433 HydrophobicContact CZ3-CG 3.88Å; W423-L436 HydrophobicContact CD2-CD1 4.12Å; W423-L436 HydrophobicContact CE3-CD1 3.23Å; W423-L436 HydrophobicContact CH2-CD1 4.36Å; W423-L436 HydrophobicContact CZ3-CB 4.36Å; W423-L436 HydrophobicContact CZ3-CD1 3.38Å; W423-L436 HydrophobicContact CZ3-CG 4.3Å; W423-W441 HydrophobicContact CB-CZ2 4.45Å; W423-W441 AromaticContact CD2-NE1 3.84Å; W423-W441 AromaticContact CG-NE1 3.91Å
424K84.4Confident84Confident133 Ų13364.7 Ų64.758%0.57829%0.289SS*.Hα-helixtrans-57.4-42.5179-75.5171.5-176174.10112.1Q420 E421 A422Q420-K424 WeakPolarHBondContact O-CG 3.11Å; Q420-K424 PolarHBondContact O-N 3.25Å; E421-K424 WeakPolarHBondContact O-CB 3.39Å; E421-K424 PolarHBondContact O-N 3.11Å; A422-K424 PolarHBondContact O-N 2.95Å
425Y81.5Confident83.7Confident114 Ų11462.1 Ų62.145%0.44728%0.279SS..Hα-helixtrans-86.8-20.8-177.5-62.7-83.5000113.4V388 K392 E421 A422 W423V388-Y425 HydrophobicContact CG1-CD1 4.02Å; V388-Y425 HydrophobicContact CG1-CD2 4.42Å; V388-Y425 HydrophobicContact CG1-CE1 3.79Å; V388-Y425 HydrophobicContact CG1-CE2 4.24Å; V388-Y425 HydrophobicContact CG1-CG 4.34Å; K392-Y425 HydrophobicContact CG-CD2 3.9Å; K392-Y425 HydrophobicContact CG-CE2 4.19Å; E421-Y425 VanDerWaalsContact O-CD2 3.24Å; E421-Y425 WeakPolarHBondContact O-CD2 3.48Å; A422-Y425 PolarHBondContact O-N 2.78Å; W423-Y425 VanDerWaalsContact C-N 3.29Å; W423-Y425 PolarHBondContact O-N 3.27Å
426N83.4Confident83.7Confident6 Ų662.1 Ų62.13%0.03228%0.279CS..Hα-helixtrans-11613.7-172.2-66.8-87.7000114.6A389 L393 A422 W423 E428 C429 L432 Q466A389-N426 PolarHBondContact O-ND2 3.25Å; L393-N426 VanDerWaalsContact CD1-OD1 3.31Å; L393-N426 WeakPolarHBondContact CD1-OD1 3.35Å; L393-N426 HydrophobicContact CD2-CB 4.49Å; A422-N426 WeakPolarHBondContact O-CB 3.23Å; A422-N426 PolarHBondContact O-N 3.21Å; A422-N426 VanDerWaalsContact O-N 3.09Å; A422-N426 PolarHBondContact O-ND2 3.37Å; W423-N426 PolarHBondContact O-N 2.89Å; N426-E428 PolarHBondContact O-N 3.41Å; N426-C429 WeakPolarHBondContact O-CB 3.37Å; N426-C429 PolarHBondContact O-N 3.48Å; N426-L432 HydrophobicContact CB-CD2 3.33Å; N426-Q466 PolarHBondContact OD1-NE2 3.49Å; N426-Q466 PolarHBondContact OD1-OE1 3.09Å
427R80.1Confident83.5Confident149 Ų14967.7 Ų67.756%0.56230%0.304SS*.THydrogen-bonded Turntrans-58.3-25.4-17473.9-178.7-167.2-161.2-5.5114.6W423 C429 R433W423-R427 WeakPolarHBondContact O-CB 3.35Å; W423-R427 PolarHBondContact O-N 2.96Å; R427-C429 VanDerWaalsContact C-N 3.34Å; R427-R433 WeakPolarHBondContact O-CD 3.38Å; R427-R433 PolarHBondContact O-NH1 3.45Å
428E79.1Confident83.3Confident128 Ų12867.1 Ų67.160%0.59831%0.31SS*.THydrogen-bonded Turntrans-81.3-16-178.5-57.6-53.3150.500112.7N426 K430 R433N426-E428 PolarHBondContact O-N 3.41Å; E428-K430 PolarHBondContact O-N 3.31Å; E428-K430 VanDerWaalsContact O-N 3.16Å; E428-R433 PolarHBondContact O-NH1 3.13Å; E428-R433 IonicContact OE2-NH1 3.43Å
429C81.1Confident83.2Confident21 Ų2167 Ų6714%0.14231%0.308CS..  trans-71.6109.2179.6-179.60000110.9N426 R427 L431 L432 R433N426-C429 WeakPolarHBondContact O-CB 3.37Å; N426-C429 PolarHBondContact O-N 3.48Å; R427-C429 VanDerWaalsContact C-N 3.34Å; C429-L431 PolarHBondContact O-N 2.63Å; C429-L432 HydrophobicContact CB-CB 3.94Å; C429-L432 PolarHBondContact O-N 3.41Å; C429-R433 WeakPolarHBondContact O-CG 3.48Å; C429-R433 PolarHBondContact O-N 2.97Å; C429-R433 VanDerWaalsContact O-N 3.09Å
430K81.5Confident83.1Confident141 Ų14169 Ų6961%0.61332%0.322SS*.Hα-helixtrans-57.4-45.8-178.8-172.7-176.8174.8-172.50112.2E428 L432 R433 D434E428-K430 PolarHBondContact O-N 3.31Å; E428-K430 VanDerWaalsContact O-N 3.16Å; K430-L432 VanDerWaalsContact C-N 3.3Å; K430-L432 PolarHBondContact O-N 3.38Å; K430-R433 PolarHBondContact O-N 3.36Å; K430-R433 VanDerWaalsContact O-N 3.14Å; K430-D434 PolarHBondContact O-N 3.25Å
431L81.3Confident83Confident55 Ų5566.8 Ų66.829%0.28831%0.31SS..Hα-helixtrans-60.4-40.5179.7-175.663.8000111.9C429 T435 Q461 V462 E465C429-L431 PolarHBondContact O-N 2.63Å; L431-T435 VanDerWaalsContact O-CB 3.28Å; L431-T435 WeakPolarHBondContact O-CB 3.4Å; L431-T435 PolarHBondContact O-N 2.98Å; L431-T435 PolarHBondContact O-OG1 3.42Å; L431-Q461 HydrophobicContact CD2-CB 4.46Å; L431-V462 HydrophobicContact CB-CG2 4.23Å; L431-V462 HydrophobicContact CD2-CG2 3.87Å; L431-V462 HydrophobicContact CG-CG2 3.85Å; L431-E465 VanDerWaalsContact CB-OE2 3.23Å; L431-E465 WeakPolarHBondContact CB-OE2 3.46Å; L431-E465 WeakPolarHBondContact CD2-OE2 3.5Å
432L83.3Confident82.9Confident0 Ų067.7 Ų67.70%032%0.318CS..Hα-helixtrans-65.4-41.2176.4-172.665.2000111.9L393 M419 W423 N426 C429 K430 T435 L436 V462L393-L432 HydrophobicContact CD2-CD1 4.11Å; L393-L432 HydrophobicContact CD2-CD2 3.98Å; M419-L432 HydrophobicContact CE-CD1 4.07Å; M419-L432 HydrophobicContact CE-CD2 4.49Å; W423-L432 HydrophobicContact CE3-CD2 4.19Å; W423-L432 HydrophobicContact CE3-CG 4.4Å; W423-L432 HydrophobicContact CZ3-CG 4.38Å; N426-L432 HydrophobicContact CB-CD2 3.33Å; C429-L432 HydrophobicContact CB-CB 3.94Å; C429-L432 PolarHBondContact O-N 3.41Å; K430-L432 VanDerWaalsContact C-N 3.3Å; K430-L432 PolarHBondContact O-N 3.38Å; L432-T435 WeakPolarHBondContact O-CB 3.18Å; L432-T435 PolarHBondContact O-N 3.31Å; L432-L436 HydrophobicContact CD1-CD1 4.47Å; L432-L436 HydrophobicContact CD1-CG 4.31Å; L432-L436 HydrophobicContact CG-CD1 4.28Å; L432-L436 HydrophobicContact CG-CG 4.42Å; L432-L436 WeakPolarHBondContact O-CB 3.25Å; L432-L436 WeakPolarHBondContact O-CG 3.45Å; L432-L436 PolarHBondContact O-N 3.01Å; L432-V462 HydrophobicContact CB-CG1 4.1Å; L432-V462 HydrophobicContact CB-CG2 4.14Å; L432-V462 HydrophobicContact CD1-CG1 4.41Å; L432-V462 HydrophobicContact CD1-CG2 4.18Å
433R83.4Confident82.4Confident94 Ų9469 Ų6936%0.35533%0.331SS..Hα-helixtrans-62.3-49177.2-64-161.7-72.8-110.9-2.7111.8W423 R427 E428 C429 K430 T435 L436 Q437W423-R433 HydrophobicContact CH2-CB 4.12Å; W423-R433 HydrophobicContact CH2-CG 3.56Å; W423-R433 HydrophobicContact CZ3-CB 4.41Å; W423-R433 HydrophobicContact CZ3-CG 3.88Å; R427-R433 WeakPolarHBondContact O-CD 3.38Å; R427-R433 PolarHBondContact O-NH1 3.45Å; E428-R433 PolarHBondContact O-NH1 3.13Å; E428-R433 IonicContact OE2-NH1 3.43Å; C429-R433 WeakPolarHBondContact O-CG 3.48Å; C429-R433 PolarHBondContact O-N 2.97Å; C429-R433 VanDerWaalsContact O-N 3.09Å; K430-R433 PolarHBondContact O-N 3.36Å; K430-R433 VanDerWaalsContact O-N 3.14Å; R433-T435 VanDerWaalsContact C-N 3.27Å; R433-T435 PolarHBondContact O-N 2.95Å; R433-L436 PolarHBondContact O-N 2.95Å; R433-Q437 PolarHBondContact O-N 2.89Å
434D81.6Confident82Confident84 Ų8475.8 Ų75.845%0.44936%0.357SS..Hα-helixtrans-62.3-40.2179.8-64.8-11.4000110.4K430 S438K430-D434 PolarHBondContact O-N 3.25Å; D434-S438 PolarHBondContact O-N 3.09Å
435T78.1Confident82.1Confident9 Ų970 Ų706%0.05533%0.334CS..Hα-helixtrans-59.7-55.3174.2-60.30000111.2L431 L432 R433 Q437 S438 F439 I458L431-T435 VanDerWaalsContact O-CB 3.28Å; L431-T435 WeakPolarHBondContact O-CB 3.4Å; L431-T435 PolarHBondContact O-N 2.98Å; L431-T435 PolarHBondContact O-OG1 3.42Å; L432-T435 WeakPolarHBondContact O-CB 3.18Å; L432-T435 PolarHBondContact O-N 3.31Å; R433-T435 VanDerWaalsContact C-N 3.27Å; R433-T435 PolarHBondContact O-N 2.95Å; T435-Q437 VanDerWaalsContact C-N 3.26Å; T435-Q437 PolarHBondContact O-N 3.28Å; T435-S438 WeakPolarHBondContact O-CA 3.36Å; T435-S438 WeakPolarHBondContact O-CB 3.41Å; T435-S438 PolarHBondContact O-N 3.14Å; T435-S438 PolarHBondContact O-OG 3.42Å; T435-F439 HydrophobicContact CG2-CD2 4.17Å; T435-F439 HydrophobicContact CG2-CE2 4.09Å; T435-F439 WeakPolarHBondContact O-CD2 3.35Å; T435-F439 PolarHBondContact O-N 3.21Å; T435-I458 HydrophobicContact CG2-CB 3.79Å; T435-I458 HydrophobicContact CG2-CD1 4.18Å; T435-I458 HydrophobicContact CG2-CG2 3.3Å; T435-I458 WeakPolarHBondContact OG1-CG2 3.48Å
436L84.6Confident82.4Confident2 Ų265.6 Ų65.61%0.0132%0.318CS..Hα-helixtrans-65.8-30.2-174.3-75.2-171.6000112.9M419 W423 L432 R433 S438 F439 S440 W441 F446 L455M419-L436 HydrophobicContact CE-CD1 3.35Å; M419-L436 HydrophobicContact CE-CD2 3.71Å; M419-L436 HydrophobicContact CE-CG 3.98Å; M419-L436 HydrophobicContact CG-CD2 4.31Å; M419-L436 HydrophobicContact SD-CD1 4.45Å; M419-L436 HydrophobicContact SD-CD2 3.9Å; W423-L436 HydrophobicContact CD2-CD1 4.12Å; W423-L436 HydrophobicContact CE3-CD1 3.23Å; W423-L436 HydrophobicContact CH2-CD1 4.36Å; W423-L436 HydrophobicContact CZ3-CB 4.36Å; W423-L436 HydrophobicContact CZ3-CD1 3.38Å; W423-L436 HydrophobicContact CZ3-CG 4.3Å; L432-L436 HydrophobicContact CD1-CD1 4.47Å; L432-L436 HydrophobicContact CD1-CG 4.31Å; L432-L436 HydrophobicContact CG-CD1 4.28Å; L432-L436 HydrophobicContact CG-CG 4.42Å; L432-L436 WeakPolarHBondContact O-CB 3.25Å; L432-L436 WeakPolarHBondContact O-CG 3.45Å; L432-L436 PolarHBondContact O-N 3.01Å; R433-L436 PolarHBondContact O-N 2.95Å; L436-S438 VanDerWaalsContact C-N 3.27Å; L436-S438 PolarHBondContact O-N 2.91Å; L436-F439 CarbonylContact O-C 3.6Å; L436-F439 PolarHBondContact O-N 3.36Å; L436-F439 VanDerWaalsContact O-N 3.13Å; L436-S440 PolarHBondContact O-N 2.98Å; L436-W441 HydrophobicContact CB-CB 3.69Å; L436-W441 HydrophobicContact CB-CG 3.98Å; L436-W441 HydrophobicContact CD1-CB 4.49Å; L436-W441 HydrophobicContact CD1-CD2 4.34Å; L436-W441 HydrophobicContact CD1-CG 3.92Å; L436-W441 HydrophobicContact CD2-CB 4.35Å; L436-W441 HydrophobicContact CD2-CG 4.4Å; L436-W441 HydrophobicContact CG-CB 4.4Å; L436-W441 HydrophobicContact CG-CG 4.34Å; L436-W441 VanDerWaalsContact O-CB 3.23Å; L436-W441 WeakPolarHBondContact O-CB 3.35Å; L436-W441 PolarHBondContact O-N 3.3Å; L436-F446 HydrophobicContact CD2-CE1 3.84Å; L436-F446 HydrophobicContact CD2-CZ 3.97Å; L436-L455 HydrophobicContact CD2-CD1 4.06Å
437Q82.1Confident82.5Confident154 Ų15469.6 Ų69.672%0.7234%0.343SS*.Hα-helixtrans-60.9-37.8171-169.3173.88.800111.8R433 T435 F439 S440R433-Q437 PolarHBondContact O-N 2.89Å; T435-Q437 VanDerWaalsContact C-N 3.26Å; T435-Q437 PolarHBondContact O-N 3.28Å; Q437-F439 PolarHBondContact O-N 3.29Å; Q437-S440 PolarHBondContact O-N 3.36Å
438S82Confident82.6Confident83 Ų8367.3 Ų67.358%0.5834%0.342SS*.Hα-helixtrans-70.6-13.8176.679.20000114.6D434 T435 L436D434-S438 PolarHBondContact O-N 3.09Å; T435-S438 WeakPolarHBondContact O-CA 3.36Å; T435-S438 WeakPolarHBondContact O-CB 3.41Å; T435-S438 PolarHBondContact O-N 3.14Å; T435-S438 PolarHBondContact O-OG 3.42Å; L436-S438 VanDerWaalsContact C-N 3.27Å; L436-S438 PolarHBondContact O-N 2.91Å
439F84.8Confident82.7Confident19 Ų1970.7 Ų70.78%0.08335%0.354CS..THydrogen-bonded Turntrans-105.513.9175.4-74.9-88000113.1T435 L436 Q437 W441 F446 V450 D451 K454 L455 I458T435-F439 HydrophobicContact CG2-CD2 4.17Å; T435-F439 HydrophobicContact CG2-CE2 4.09Å; T435-F439 WeakPolarHBondContact O-CD2 3.35Å; T435-F439 PolarHBondContact O-N 3.21Å; L436-F439 CarbonylContact O-C 3.6Å; L436-F439 PolarHBondContact O-N 3.36Å; L436-F439 VanDerWaalsContact O-N 3.13Å; Q437-F439 PolarHBondContact O-N 3.29Å; F439-W441 VanDerWaalsContact C-N 3.3Å; F439-W441 PolarHBondContact O-N 3.41Å; F439-F446 HydrophobicContact CB-CD1 3.96Å; F439-F446 HydrophobicContact CB-CE1 3.78Å; F439-F446 WeakPolarHBondContact O-CD1 3.5Å; F439-V450 HydrophobicContact CD1-CG1 3.81Å; F439-V450 HydrophobicContact CE1-CG1 4.19Å; F439-D451 HydrophobicContact CE1-CB 4.29Å; F439-K454 HydrophobicContact CE1-CB 4.32Å; F439-K454 HydrophobicContact CZ-CB 3.91Å; F439-K454 HydrophobicContact CZ-CD 4.03Å; F439-K454 HydrophobicContact CZ-CG 3.87Å; F439-L455 HydrophobicContact CD2-CD1 4.15Å; F439-L455 HydrophobicContact CE1-CB 4.07Å; F439-L455 HydrophobicContact CE2-CD1 4.26Å; F439-L455 HydrophobicContact CG-CD1 4.45Å; F439-L455 HydrophobicContact CZ-CB 4.05Å; F439-I458 HydrophobicContact CE2-CD1 3.78Å; F439-I458 HydrophobicContact CZ-CD1 4.17Å
440S86.8Confident82.8Confident42 Ų4270.5 Ų70.529%0.29435%0.353SS..THydrogen-bonded Turntrans59.337.8-179.4-46.30000113.4L436 Q437 T447 D448L436-S440 PolarHBondContact O-N 2.98Å; Q437-S440 PolarHBondContact O-N 3.36Å; S440-T447 VanDerWaalsContact CB-OG1 3.23Å; S440-T447 WeakPolarHBondContact CB-OG1 3.4Å; S440-T447 PolarHBondContact O-N 2.89Å; S440-T447 PolarHBondContact O-OG1 3.05Å; S440-D448 WeakPolarHBondContact CB-OD2 3.5Å; S440-D448 PolarHBondContact OG-OD2 3.16Å
441W85.8Confident83Confident24 Ų2468 Ų689%0.09135%0.346CS..BIsolated β-bridgetrans-77.2123.9173.1-178-107.5000111.1M419 Q420 W423 L436 F439 F446M419-W441 HydrophobicContact CB-CH2 3.73Å; M419-W441 HydrophobicContact CB-CZ2 4.42Å; M419-W441 HydrophobicContact CB-CZ3 3.81Å; M419-W441 HydrophobicContact CG-CD2 4.34Å; M419-W441 HydrophobicContact CG-CE3 4.03Å; M419-W441 HydrophobicContact CG-CH2 3.74Å; M419-W441 HydrophobicContact CG-CZ2 4.05Å; M419-W441 HydrophobicContact CG-CZ3 3.71Å; Q420-W441 HydrophobicContact CB-CH2 4.19Å; Q420-W441 HydrophobicContact CB-CZ2 4.35Å; W423-W441 HydrophobicContact CB-CZ2 4.45Å; W423-W441 AromaticContact CD2-NE1 3.84Å; W423-W441 AromaticContact CG-NE1 3.91Å; L436-W441 HydrophobicContact CB-CB 3.69Å; L436-W441 HydrophobicContact CB-CG 3.98Å; L436-W441 HydrophobicContact CD1-CB 4.49Å; L436-W441 HydrophobicContact CD1-CD2 4.34Å; L436-W441 HydrophobicContact CD1-CG 3.92Å; L436-W441 HydrophobicContact CD2-CB 4.35Å; L436-W441 HydrophobicContact CD2-CG 4.4Å; L436-W441 HydrophobicContact CG-CB 4.4Å; L436-W441 HydrophobicContact CG-CG 4.34Å; L436-W441 VanDerWaalsContact O-CB 3.23Å; L436-W441 WeakPolarHBondContact O-CB 3.35Å; L436-W441 PolarHBondContact O-N 3.3Å; F439-W441 VanDerWaalsContact C-N 3.3Å; F439-W441 PolarHBondContact O-N 3.41Å; W441-F446 HydrophobicContact CB-CD1 4.08Å; W441-F446 HydrophobicContact CB-CE1 4.05Å; W441-F446 HydrophobicContact CD2-CD1 4.47Å; W441-F446 HydrophobicContact CD2-CE1 4.29Å; W441-F446 HydrophobicContact CD2-CZ 4.46Å; W441-F446 AromaticContact CE3-CD1 3.64Å; W441-F446 HydrophobicContact CE3-CD1 3.64Å; W441-F446 AromaticContact CE3-CD2 3.69Å; W441-F446 HydrophobicContact CE3-CD2 3.69Å; W441-F446 AromaticContact CE3-CE1 3.63Å; W441-F446 HydrophobicContact CE3-CE1 3.63Å; W441-F446 AromaticContact CE3-CE2 3.65Å; W441-F446 HydrophobicContact CE3-CE2 3.65Å; W441-F446 AromaticContact CE3-CG 3.68Å; W441-F446 HydrophobicContact CE3-CG 3.68Å; W441-F446 AromaticContact CE3-CZ 3.64Å; W441-F446 HydrophobicContact CE3-CZ 3.64Å; W441-F446 HydrophobicContact CZ3-CD1 4.49Å; W441-F446 AromaticContact CZ3-CD2 3.71Å; W441-F446 HydrophobicContact CZ3-CD2 3.71Å; W441-F446 HydrophobicContact CZ3-CE1 4.45Å; W441-F446 AromaticContact CZ3-CE2 3.64Å; W441-F446 HydrophobicContact CZ3-CE2 3.64Å; W441-F446 HydrophobicContact CZ3-CG 4.15Å; W441-F446 HydrophobicContact CZ3-CZ 4.04Å
442N82.1Confident83.1Confident104 Ų10467.5 Ų67.556%0.55634%0.34SS*.  trans-100.39.9-178.769.712.3000114.2R444 G445 T447N442-R444 PolarHBondContact OD1-N 3.06Å; N442-G445 PolarHBondContact N-O 3Å; N442-G445 VanDerWaalsContact N-O 3.11Å; N442-G445 PolarHBondContact OD1-N 3.43Å; N442-G445 PolarHBondContact OD1-O 3.07Å; N442-T447 HydrophobicContact CB-CG2 4.26Å; N442-T447 WeakPolarHBondContact ND2-CG2 3.28Å
443G77.2Confident82.9Confident27 Ų2771.6 Ų71.628%0.27836%0.361SS..SBendtrans90.9-11.3-175.700000114.9
444R78.7Confident82.9Confident203 Ų20372.6 Ų72.677%0.76637%0.369SS*.SBendtrans-122-33.7173.4-70.1-171.2-179-147.51.4113.3N442N442-R444 PolarHBondContact OD1-N 3.06Å
445G85.7Confident83Confident10 Ų1068.6 Ų68.610%0.10335%0.347CS..SBendtrans-163.9167.5-18000000111.6N416 N442N416-G445 VanDerWaalsContact OD1-CA 3.27Å; N416-G445 WeakPolarHBondContact OD1-CA 3.34Å; N442-G445 PolarHBondContact N-O 3Å; N442-G445 VanDerWaalsContact N-O 3.11Å; N442-G445 PolarHBondContact OD1-N 3.43Å; N442-G445 PolarHBondContact OD1-O 3.07Å
446F88.4Confident83.3Confident22 Ų2268.2 Ų68.210%0.09635%0.345CS..BIsolated β-bridgetrans-78126.2168.6-60.7-77.1000109.5L415 N416 M419 L436 F439 W441 V450 L455L415-F446 HydrophobicContact CD2-CE2 4.48Å; L415-F446 HydrophobicContact CG-CE2 4.24Å; N416-F446 WeakPolarHBondContact OD1-CD2 3.31Å; N416-F446 PolarHBondContact OD1-N 3.03Å; M419-F446 HydrophobicContact CB-CE2 3.94Å; M419-F446 HydrophobicContact CB-CZ 4.25Å; M419-F446 HydrophobicContact CG-CE2 3.84Å; M419-F446 HydrophobicContact CG-CZ 3.63Å; M419-F446 HydrophobicContact SD-CZ 4.17Å; L436-F446 HydrophobicContact CD2-CE1 3.84Å; L436-F446 HydrophobicContact CD2-CZ 3.97Å; F439-F446 HydrophobicContact CB-CD1 3.96Å; F439-F446 HydrophobicContact CB-CE1 3.78Å; F439-F446 WeakPolarHBondContact O-CD1 3.5Å; W441-F446 HydrophobicContact CB-CD1 4.08Å; W441-F446 HydrophobicContact CB-CE1 4.05Å; W441-F446 HydrophobicContact CD2-CD1 4.47Å; W441-F446 HydrophobicContact CD2-CE1 4.29Å; W441-F446 HydrophobicContact CD2-CZ 4.46Å; W441-F446 AromaticContact CE3-CD1 3.64Å; W441-F446 HydrophobicContact CE3-CD1 3.64Å; W441-F446 AromaticContact CE3-CD2 3.69Å; W441-F446 HydrophobicContact CE3-CD2 3.69Å; W441-F446 AromaticContact CE3-CE1 3.63Å; W441-F446 HydrophobicContact CE3-CE1 3.63Å; W441-F446 AromaticContact CE3-CE2 3.65Å; W441-F446 HydrophobicContact CE3-CE2 3.65Å; W441-F446 AromaticContact CE3-CG 3.68Å; W441-F446 HydrophobicContact CE3-CG 3.68Å; W441-F446 AromaticContact CE3-CZ 3.64Å; W441-F446 HydrophobicContact CE3-CZ 3.64Å; W441-F446 HydrophobicContact CZ3-CD1 4.49Å; W441-F446 AromaticContact CZ3-CD2 3.71Å; W441-F446 HydrophobicContact CZ3-CD2 3.71Å; W441-F446 HydrophobicContact CZ3-CE1 4.45Å; W441-F446 AromaticContact CZ3-CE2 3.64Å; W441-F446 HydrophobicContact CZ3-CE2 3.64Å; W441-F446 HydrophobicContact CZ3-CG 4.15Å; W441-F446 HydrophobicContact CZ3-CZ 4.04Å; F446-V450 HydrophobicContact CB-CG2 3.4Å; F446-V450 HydrophobicContact CD1-CG2 3.56Å; F446-V450 HydrophobicContact CD2-CG2 3.51Å; F446-V450 HydrophobicContact CE1-CG2 4.15Å; F446-V450 HydrophobicContact CE2-CG2 4.13Å; F446-V450 HydrophobicContact CG-CG2 3.19Å; F446-V450 HydrophobicContact CZ-CG2 4.41Å; F446-L455 HydrophobicContact CE1-CD2 4.36Å; F446-L455 HydrophobicContact CE2-CD2 4.13Å; F446-L455 HydrophobicContact CZ-CD1 4.45Å; F446-L455 HydrophobicContact CZ-CD2 3.61Å
447T83.9Confident83.1Confident91 Ų9173.8 Ų73.856%0.55837%0.371SS*.SBendtrans-82-21.3178.7590000112.8S440 N442S440-T447 VanDerWaalsContact CB-OG1 3.23Å; S440-T447 WeakPolarHBondContact CB-OG1 3.4Å; S440-T447 PolarHBondContact O-N 2.89Å; S440-T447 PolarHBondContact O-OG1 3.05Å; N442-T447 HydrophobicContact CB-CG2 4.26Å; N442-T447 WeakPolarHBondContact ND2-CG2 3.28Å
448D83.8Confident83.1Confident100 Ų10067.8 Ų67.854%0.53534%0.343SS..SBendtrans-116.8164.4178.1-64.4-45.9000111.4S440 V450S440-D448 WeakPolarHBondContact CB-OD2 3.5Å; S440-D448 PolarHBondContact OG-OD2 3.16Å; D448-V450 PolarHBondContact O-N 3.43Å
449K81.5Confident83.2Confident200 Ų20063.8 Ų63.887%0.8732%0.315SS*.  trans-64.1122.1176.6-171.7175.7-177.4176.10110.6
450V82.8Confident83.1Confident17 Ų1765.4 Ų65.410%0.10332%0.322CS..  trans-84.8129.2-175.9-177.40000111.5L415 F439 F446 D448 R452 L455L415-V450 HydrophobicContact CD2-CB 4.42Å; L415-V450 HydrophobicContact CD2-CG1 4.4Å; F439-V450 HydrophobicContact CD1-CG1 3.81Å; F439-V450 HydrophobicContact CE1-CG1 4.19Å; F446-V450 HydrophobicContact CB-CG2 3.4Å; F446-V450 HydrophobicContact CD1-CG2 3.56Å; F446-V450 HydrophobicContact CD2-CG2 3.51Å; F446-V450 HydrophobicContact CE1-CG2 4.15Å; F446-V450 HydrophobicContact CE2-CG2 4.13Å; F446-V450 HydrophobicContact CG-CG2 3.19Å; F446-V450 HydrophobicContact CZ-CG2 4.41Å; D448-V450 PolarHBondContact O-N 3.43Å; V450-R452 VanDerWaalsContact C-N 3.35Å; V450-R452 PolarHBondContact O-N 2.68Å; V450-L455 HydrophobicContact CG1-CB 4.01Å; V450-L455 HydrophobicContact CG1-CD2 3.68Å; V450-L455 HydrophobicContact CG1-CG 4.43Å
451D84.4Confident82.8Confident88 Ų8868 Ų6847%0.47133%0.33SS..  trans-72.593.3160.6-174.2-22.8000109.1F439 L453 K454 L455F439-D451 HydrophobicContact CE1-CB 4.29Å; D451-L453 PolarHBondContact O-N 2.98Å; D451-L453 PolarHBondContact OD1-N 3.41Å; D451-K454 HydrophobicContact CB-CB 3.96Å; D451-K454 PolarHBondContact O-N 2.97Å; D451-K454 PolarHBondContact OD1-N 3.47Å; D451-K454 VanDerWaalsContact OD1-N 3.16Å; D451-L455 PolarHBondContact O-N 3.09Å
452R84.9Confident82.7Confident44 Ų4466.8 Ų66.817%0.16633%0.325CS..Hα-helixtrans-60-32.6-174.4-61.9-171.3-176.61735.4113.1C400 P403 E411 D412 L415 V450 A456C400-R452 HydrophobicContact CB-CB 3.97Å; C400-R452 VanDerWaalsContact CB-O 3.28Å; C400-R452 WeakPolarHBondContact CB-O 3.34Å; C400-R452 PolarHBondContact SG-O 2.97Å; P403-R452 VanDerWaalsContact CG-NH1 3.26Å; E411-R452 VanDerWaalsContact CB-NH2 3.28Å; E411-R452 IonicContact OE2-CZ 2.68Å; E411-R452 IonicContact OE2-NH1 3.72Å; E411-R452 PolarHBondContact OE2-NH1 2.99Å; E411-R452 IonicContact OE2-NH2 2.77Å; E411-R452 PolarHBondContact OE2-NH2 2.66Å; D412-R452 IonicContact OD1-CZ 2.59Å; D412-R452 IonicContact OD1-NE 3.13Å; D412-R452 IonicContact OD1-NH2 2.87Å; D412-R452 PolarHBondContact OD1-NH2 3.13Å; L415-R452 HydrophobicContact CD2-CG 3.95Å; V450-R452 VanDerWaalsContact C-N 3.35Å; V450-R452 PolarHBondContact O-N 2.68Å; R452-A456 WeakPolarHBondContact O-CB 3.22Å; R452-A456 PolarHBondContact O-N 3.48Å
453L79.1Confident82.6Confident86 Ų8662.7 Ų62.745%0.4530%0.303SS..Hα-helixtrans-72.5-43.9179.1-72.2173000110.7D451 L455 A456 E457D451-L453 PolarHBondContact O-N 2.98Å; D451-L453 PolarHBondContact OD1-N 3.41Å; L453-L455 VanDerWaalsContact C-N 3.33Å; L453-A456 PolarHBondContact O-N 3.2Å; L453-E457 PolarHBondContact O-N 3.42Å
454K82.5Confident82.7Confident116 Ų11665.5 Ų65.550%0.50431%0.309SS..Hα-helixtrans-64.3-39.8175.8-165.1-178.1179.6-176.90111.4F439 D451 E457 I458F439-K454 HydrophobicContact CE1-CB 4.32Å; F439-K454 HydrophobicContact CZ-CB 3.91Å; F439-K454 HydrophobicContact CZ-CD 4.03Å; F439-K454 HydrophobicContact CZ-CG 3.87Å; D451-K454 HydrophobicContact CB-CB 3.96Å; D451-K454 PolarHBondContact O-N 2.97Å; D451-K454 PolarHBondContact OD1-N 3.47Å; D451-K454 VanDerWaalsContact OD1-N 3.16Å; K454-E457 PolarHBondContact O-N 3.15Å; K454-I458 HydrophobicContact CG-CD1 4.1Å; K454-I458 WeakPolarHBondContact O-CD1 3.44Å; K454-I458 WeakPolarHBondContact O-CG1 3.33Å; K454-I458 PolarHBondContact O-N 3.46Å
455L84.6Confident82.6Confident0 Ų060.6 Ų60.60%030%0.295CS..Hα-helixtrans-61.2-46.1173.7-179.363000111.3V396 L436 F439 F446 V450 D451 L453 E457 I458 V459V396-L455 HydrophobicContact CG1-CD2 4.38Å; L436-L455 HydrophobicContact CD2-CD1 4.06Å; F439-L455 HydrophobicContact CD2-CD1 4.15Å; F439-L455 HydrophobicContact CE1-CB 4.07Å; F439-L455 HydrophobicContact CE2-CD1 4.26Å; F439-L455 HydrophobicContact CG-CD1 4.45Å; F439-L455 HydrophobicContact CZ-CB 4.05Å; F446-L455 HydrophobicContact CE1-CD2 4.36Å; F446-L455 HydrophobicContact CE2-CD2 4.13Å; F446-L455 HydrophobicContact CZ-CD1 4.45Å; F446-L455 HydrophobicContact CZ-CD2 3.61Å; V450-L455 HydrophobicContact CG1-CB 4.01Å; V450-L455 HydrophobicContact CG1-CD2 3.68Å; V450-L455 HydrophobicContact CG1-CG 4.43Å; D451-L455 PolarHBondContact O-N 3.09Å; L453-L455 VanDerWaalsContact C-N 3.33Å; L455-E457 VanDerWaalsContact C-N 3.34Å; L455-E457 PolarHBondContact O-N 2.92Å; L455-I458 PolarHBondContact O-N 3.01Å; L455-V459 HydrophobicContact CD1-CG2 3.98Å; L455-V459 HydrophobicContact CG-CG2 4.25Å; L455-V459 WeakPolarHBondContact O-CB 3.29Å; L455-V459 WeakPolarHBondContact O-CG2 3.26Å; L455-V459 PolarHBondContact O-N 3.38Å
456A83.5Confident82Confident0 Ų061.4 Ų61.40%030%0.296CS..Hα-helixtrans-63.1-37179.300000113.4I397 C400 I401 R452 L453 K460I397-A456 HydrophobicContact CG2-CB 4.41Å; C400-A456 HydrophobicContact CB-CB 3.85Å; I401-A456 HydrophobicContact CG1-CB 4.49Å; R452-A456 WeakPolarHBondContact O-CB 3.22Å; R452-A456 PolarHBondContact O-N 3.48Å; L453-A456 PolarHBondContact O-N 3.2Å; A456-K460 WeakPolarHBondContact O-CB 3.18Å; A456-K460 PolarHBondContact O-N 3.26Å
457E81.4Confident81.1Confident119 Ų11962.8 Ų62.856%0.55631%0.306SS*.Hα-helixtrans-67.6-41.4178-172.8165.3-15500111.9L453 K454 L455 K460 Q461L453-E457 PolarHBondContact O-N 3.42Å; K454-E457 PolarHBondContact O-N 3.15Å; L455-E457 VanDerWaalsContact C-N 3.34Å; L455-E457 PolarHBondContact O-N 2.92Å; E457-K460 WeakPolarHBondContact O-CB 3.35Å; E457-K460 PolarHBondContact O-N 3.42Å; E457-Q461 PolarHBondContact O-N 3.2Å
458I80.9Confident80.1Confident28 Ų2862.2 Ų62.214%0.14430%0.303CS..Hα-helixtrans-75.9-37.7179.8-57.5162.1000111.2T435 F439 K454 L455 K460 Q461 V462T435-I458 HydrophobicContact CG2-CB 3.79Å; T435-I458 HydrophobicContact CG2-CD1 4.18Å; T435-I458 HydrophobicContact CG2-CG2 3.3Å; T435-I458 WeakPolarHBondContact OG1-CG2 3.48Å; F439-I458 HydrophobicContact CE2-CD1 3.78Å; F439-I458 HydrophobicContact CZ-CD1 4.17Å; K454-I458 HydrophobicContact CG-CD1 4.1Å; K454-I458 WeakPolarHBondContact O-CD1 3.44Å; K454-I458 WeakPolarHBondContact O-CG1 3.33Å; K454-I458 PolarHBondContact O-N 3.46Å; L455-I458 PolarHBondContact O-N 3.01Å; I458-K460 PolarHBondContact O-N 3.37Å; I458-Q461 WeakPolarHBondContact O-CB 3.23Å; I458-Q461 PolarHBondContact O-N 3Å; I458-V462 WeakPolarHBondContact O-CG2 3.49Å; I458-V462 PolarHBondContact O-N 2.85Å
459V84.8Confident78.8Confident0 Ų060.5 Ų60.50%030%0.298CS..Hα-helixtrans-61.1-32.8172.1173.20000111.1L393 V396 I397 L455 V462 I463L393-V459 HydrophobicContact CB-CG1 3.9Å; L393-V459 HydrophobicContact CD2-CG1 3.92Å; L393-V459 HydrophobicContact CG-CG1 4.46Å; L393-V459 WeakPolarHBondContact O-CG1 3.45Å; V396-V459 HydrophobicContact CG1-CG2 4.25Å; I397-V459 HydrophobicContact CD1-CB 4.46Å; I397-V459 HydrophobicContact CD1-CG1 4.04Å; I397-V459 HydrophobicContact CG1-CB 4.1Å; I397-V459 HydrophobicContact CG1-CG1 3.77Å; L455-V459 HydrophobicContact CD1-CG2 3.98Å; L455-V459 HydrophobicContact CG-CG2 4.25Å; L455-V459 WeakPolarHBondContact O-CB 3.29Å; L455-V459 WeakPolarHBondContact O-CG2 3.26Å; L455-V459 PolarHBondContact O-N 3.38Å; V459-V462 WeakPolarHBondContact O-CB 3.24Å; V459-V462 PolarHBondContact O-N 3.17Å; V459-I463 WeakPolarHBondContact O-CG1 3.32Å; V459-I463 PolarHBondContact O-N 2.83Å
460K82.1Confident77.5Confident52 Ų5256.2 Ų56.223%0.22628%0.281CS..Hα-helixtrans-65-41171.7-177.2176-179-84.30112.3L365 I397 A456 E457 I458 V462 I463 E464L365-K460 HydrophobicContact CB-CD 4.24Å; L365-K460 HydrophobicContact CD2-CD 3.43Å; L365-K460 VanDerWaalsContact CD2-CD 3.43Å; L365-K460 HydrophobicContact CG-CD 4.42Å; L365-K460 WeakPolarHBondContact O-CD 3.38Å; L365-K460 WeakPolarHBondContact O-CE 3.2Å; I397-K460 HydrophobicContact CD1-CB 3.97Å; A456-K460 WeakPolarHBondContact O-CB 3.18Å; A456-K460 PolarHBondContact O-N 3.26Å; E457-K460 WeakPolarHBondContact O-CB 3.35Å; E457-K460 PolarHBondContact O-N 3.42Å; I458-K460 PolarHBondContact O-N 3.37Å; K460-V462 VanDerWaalsContact C-N 3.29Å; K460-V462 PolarHBondContact O-N 2.61Å; K460-I463 WeakPolarHBondContact O-CB 3.23Å; K460-I463 PolarHBondContact O-N 2.77Å; K460-E464 WeakPolarHBondContact CE-OE1 3.3Å; K460-E464 IonicContact NZ-OE1 3.31Å; K460-E464 PolarHBondContact NZ-OE1 3.41Å; K460-E464 WeakPolarHBondContact O-CG 3.45Å; K460-E464 PolarHBondContact O-N 3.44Å
461Q80.8Confident75.7Confident96 Ų9663.6 Ų63.645%0.44932%0.315SS..Hα-helixtrans-62.5-38.4174.8-67.6173.4-500111.6L431 E457 I458 E464 E465L431-Q461 HydrophobicContact CD2-CB 4.46Å; E457-Q461 PolarHBondContact O-N 3.2Å; I458-Q461 WeakPolarHBondContact O-CB 3.23Å; I458-Q461 PolarHBondContact O-N 3Å; Q461-E464 PolarHBondContact O-N 3.43Å; Q461-E465 PolarHBondContact O-N 3.04Å
462V82.8Confident73.8Confident0 Ų064.2 Ų64.20%033%0.326CS..Hα-helixtrans-60.8-44.9173.3172.70000111.3L393 L431 L432 I458 V459 K460 E464 E465 Q466L393-V462 HydrophobicContact CD1-CG1 3.82Å; L431-V462 HydrophobicContact CB-CG2 4.23Å; L431-V462 HydrophobicContact CD2-CG2 3.87Å; L431-V462 HydrophobicContact CG-CG2 3.85Å; L432-V462 HydrophobicContact CB-CG1 4.1Å; L432-V462 HydrophobicContact CB-CG2 4.14Å; L432-V462 HydrophobicContact CD1-CG1 4.41Å; L432-V462 HydrophobicContact CD1-CG2 4.18Å; I458-V462 WeakPolarHBondContact O-CG2 3.49Å; I458-V462 PolarHBondContact O-N 2.85Å; V459-V462 WeakPolarHBondContact O-CB 3.24Å; V459-V462 PolarHBondContact O-N 3.17Å; K460-V462 VanDerWaalsContact C-N 3.29Å; K460-V462 PolarHBondContact O-N 2.61Å; V462-E464 VanDerWaalsContact C-N 3.35Å; V462-E465 PolarHBondContact O-N 3.31Å; V462-Q466 HydrophobicContact CG1-CG 4.49Å; V462-Q466 WeakPolarHBondContact O-CB 3.27Å; V462-Q466 VanDerWaalsContact O-CG 3.31Å; V462-Q466 WeakPolarHBondContact O-CG 3.45Å; V462-Q466 PolarHBondContact O-N 3.46Å
463I81.1Confident71.7Confident17 Ų1773.3 Ų73.39%0.08737%0.37CS..Hα-helixtrans-60.2-46.2175.4-70.3170000110.4L390 L393 R394 I397 V459 K460 Q466 T467L390-I463 HydrophobicContact CD2-CB 4.45Å; L390-I463 HydrophobicContact CD2-CG1 4.36Å; L390-I463 HydrophobicContact CD2-CG2 4.21Å; L393-I463 HydrophobicContact CB-CD1 3.75Å; L393-I463 HydrophobicContact CB-CG1 3.67Å; L393-I463 HydrophobicContact CD1-CG1 3.89Å; L393-I463 HydrophobicContact CG-CG1 4.45Å; R394-I463 HydrophobicContact CG-CD1 3.8Å; I397-I463 HydrophobicContact CD1-CD1 3.61Å; V459-I463 WeakPolarHBondContact O-CG1 3.32Å; V459-I463 PolarHBondContact O-N 2.83Å; K460-I463 WeakPolarHBondContact O-CB 3.23Å; K460-I463 PolarHBondContact O-N 2.77Å; I463-Q466 PolarHBondContact O-N 3.34Å; I463-T467 HydrophobicContact CG2-CG2 4.5Å; I463-T467 WeakPolarHBondContact O-CG2 3.46Å; I463-T467 PolarHBondContact O-N 3.41Å; I463-T467 PolarHBondContact O-OG1 3.31Å
464E78.4Confident71.3Confident87 Ų8772.7 Ų72.741%0.40737%0.366SS..Hα-helixtrans-60.3-48.2-180-73.8171.8179.900111.3K460 Q461 V462 Q466 T467 T468K460-E464 WeakPolarHBondContact CE-OE1 3.3Å; K460-E464 IonicContact NZ-OE1 3.31Å; K460-E464 PolarHBondContact NZ-OE1 3.41Å; K460-E464 WeakPolarHBondContact O-CG 3.45Å; K460-E464 PolarHBondContact O-N 3.44Å; Q461-E464 PolarHBondContact O-N 3.43Å; V462-E464 VanDerWaalsContact C-N 3.35Å; E464-Q466 PolarHBondContact O-N 3.19Å; E464-T467 WeakPolarHBondContact CA-OG1 3.25Å; E464-T467 PolarHBondContact O-N 3.33Å; E464-T467 PolarHBondContact O-OG1 2.78Å; E464-T468 WeakPolarHBondContact O-CG2 3.4Å; E464-T468 PolarHBondContact O-N 3.04Å; E464-T468 PolarHBondContact O-OG1 3.19Å; E464-T468 VanDerWaalsContact O-OG1 3.11Å
465E78.1Confident70.7Confident99 Ų9970.4 Ų70.446%0.46336%0.359SS..Hα-helixtrans-60.1-45.6177.8-171-179.5-161.400111.8L431 Q461 V462 T467 T468 S469L431-E465 VanDerWaalsContact CB-OE2 3.23Å; L431-E465 WeakPolarHBondContact CB-OE2 3.46Å; L431-E465 WeakPolarHBondContact CD2-OE2 3.5Å; Q461-E465 PolarHBondContact O-N 3.04Å; V462-E465 PolarHBondContact O-N 3.31Å; E465-T467 PolarHBondContact O-N 3.03Å; E465-T468 WeakPolarHBondContact CA-OG1 3.32Å; E465-T468 PolarHBondContact O-N 2.85Å; E465-T468 PolarHBondContact O-OG1 3.21Å; E465-S469 PolarHBondContact O-N 3.07Å; E465-S469 PolarHBondContact O-OG 3.1Å
466Q72.2Confident70Confident27 Ų2774.3 Ų74.313%0.12638%0.379CS..Hα-helixtrans-66.1-34.9178-72.2-175.312.500112.7L390 N426 V462 I463 E464 S469 H470L390-Q466 HydrophobicContact CD2-CB 3.96Å; N426-Q466 PolarHBondContact OD1-NE2 3.49Å; N426-Q466 PolarHBondContact OD1-OE1 3.09Å; V462-Q466 HydrophobicContact CG1-CG 4.49Å; V462-Q466 WeakPolarHBondContact O-CB 3.27Å; V462-Q466 VanDerWaalsContact O-CG 3.31Å; V462-Q466 WeakPolarHBondContact O-CG 3.45Å; V462-Q466 PolarHBondContact O-N 3.46Å; I463-Q466 PolarHBondContact O-N 3.34Å; E464-Q466 PolarHBondContact O-N 3.19Å; Q466-S469 WeakPolarHBondContact CA-OG 3.41Å; Q466-S469 PolarHBondContact O-OG 2.75Å; Q466-H470 PolarHBondContact O-CD2 3Å
467T69.5Low69.2Low51 Ų5178.7 Ų78.731%0.31340%0.401SS..Hα-helixtrans-70.7-39.6174.447.80000112.6L390 I463 E464 E465 H470 E471L390-T467 HydrophobicContact CD1-CG2 3.88Å; L390-T467 HydrophobicContact CD2-CG2 4.43Å; I463-T467 HydrophobicContact CG2-CG2 4.5Å; I463-T467 WeakPolarHBondContact O-CG2 3.46Å; I463-T467 PolarHBondContact O-N 3.41Å; I463-T467 PolarHBondContact O-OG1 3.31Å; E464-T467 WeakPolarHBondContact CA-OG1 3.25Å; E464-T467 PolarHBondContact O-N 3.33Å; E464-T467 PolarHBondContact O-OG1 2.78Å; E465-T467 PolarHBondContact O-N 3.03Å; T467-H470 PolarHBondContact O-N 2.96Å; T467-E471 PolarHBondContact O-N 2.94Å
468T63.1Low68.4Low79 Ų7976.2 Ų76.249%0.48539%0.392SS..Hα-helixtrans-71.1-29.8179.351.60000113.8E464 E465 H470 E471 S472E464-T468 WeakPolarHBondContact O-CG2 3.4Å; E464-T468 PolarHBondContact O-N 3.04Å; E464-T468 PolarHBondContact O-OG1 3.19Å; E464-T468 VanDerWaalsContact O-OG1 3.11Å; E465-T468 WeakPolarHBondContact CA-OG1 3.32Å; E465-T468 PolarHBondContact O-N 2.85Å; E465-T468 PolarHBondContact O-OG1 3.21Å; T468-H470 VanDerWaalsContact C-N 3.35Å; T468-E471 PolarHBondContact O-N 2.93Å; T468-S472 PolarHBondContact O-OG 3.05Å
469S56.5Low67.6Low64 Ų6479.4 Ų79.445%0.44841%0.408SS..Hα-helixtrans-74.9-23.9177.737.10000113.1E465 Q466E465-S469 PolarHBondContact O-N 3.07Å; E465-S469 PolarHBondContact O-OG 3.1Å; Q466-S469 WeakPolarHBondContact CA-OG 3.41Å; Q466-S469 PolarHBondContact O-OG 2.75Å
470H53.1Low66.3Low111 Ų11185.1 Ų85.151%0.51444%0.437SS..Hα-helixtrans-81-22172.4-86.3-59.4000114.4S386 Q466 T467 T468 S472S386-H470 PolarHBondContact OG-CD2 2.88Å; S386-H470 PolarHBondContact OG-NE2 3.11Å; Q466-H470 PolarHBondContact O-CD2 3Å; T467-H470 PolarHBondContact O-N 2.96Å; T468-H470 VanDerWaalsContact C-N 3.35Å; H470-S472 VanDerWaalsContact C-N 3.3Å
471E46.4Very low65.1Low171 Ų17187.6 Ų87.680%0.79945%0.454SS*.THydrogen-bonded Turntrans-82-7.1174.6-73.6-178.8164.400113.3T467 T468T467-E471 PolarHBondContact O-N 2.94Å; T468-E471 PolarHBondContact O-N 2.93Å
472S44.7Very low63.8Low101 Ų10186.9 Ų86.971%0.70645%0.454SS*.THydrogen-bonded Turntrans-106.410.5-173.8-500000114.5T468 H470T468-S472 PolarHBondContact O-OG 3.05Å; H470-S472 VanDerWaalsContact C-N 3.3Å
473Q39.8Very low62.1Low236 Ų23694.8 Ų94.8100%1.10350%0.495SS*.  trans-1210179.2-79.7-170.2-18.800112.7

Retrieved 473 of 473 residues in 137.6 ms (Link to these results)