A0A096N1N4_PAPAN Loading...

Phosphatidylserine synthase

Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.

AlphaFold DB (H9G077), UniProt , Accession A0A096N1N4, Species PAPAN (Papio anubis, Olive baboon), Gene PTDSS2, Length 487 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	45.7	Very low	32.7	Very low	243 Å²	243	165.4 Å²	165.4	100%	1.197	87%	0.871	S	S	*	*				0	99.2	0	-80	177.8	174.2	0	0	109.6
2	R	30.7	Very low	33.3	Very low	244 Å²	244	162.1 Å²	162.1	92%	0.921	87%	0.866	S	S	*	*			trans	168.7	136.3	164.5	-103.4	174	-175	-169.1	2.5	109.3
3	R	30.8	Very low	33.5	Very low	255 Å²	255	167 Å²	167	96%	0.962	87%	0.865	S	S	*	*			trans	39.3	141.3	150.8	-83.7	177.4	164.7	175.9	-5	119.3
4	G	29.4	Very low	33.8	Very low	77 Å²	77	162.6 Å²	162.6	79%	0.794	85%	0.852	S	S	*	*			cis	175.9	-169.2	20.9	0	0	0	0	0	112.3
5	E	37.3	Very low	33.3	Very low	158 Å²	158	162.9 Å²	162.9	74%	0.738	85%	0.848	S	S	*	*			trans	-66.3	163.2	-168.7	-74.5	174.1	92.8	0	0	120.1
6	R	33.2	Very low	33.3	Very low	193 Å²	193	159.8 Å²	159.8	73%	0.728	84%	0.844	S	S	*	*			trans	72.6	149.7	146.3	-77.9	165.4	-163.2	-123.9	3.5	117.5
7	R	31.4	Very low	33.2	Very low	218 Å²	218	157.8 Å²	157.8	82%	0.823	84%	0.843	S	S	*	*			cis	-170	157.3	29.2	-130	164.3	-174.4	179.8	2	110
8	D	36.9	Very low	33.3	Very low	162 Å²	162	156.5 Å²	156.5	87%	0.866	84%	0.841	S	S	*	*			trans	-62.6	153.6	166.6	-73.9	-55.6	0	0	0	114.9
9	A	30.7	Very low	33.8	Very low	109 Å²	109	154.2 Å²	154.2	90%	0.901	84%	0.835	S	S	*	*				163.3	137.9	129.3	0	0	0	0	0	114.5
10	G	28.4	Very low	33.4	Very low	81 Å²	81	151.6 Å²	151.6	84%	0.835	84%	0.836	S	S	*	*			trans	117.3	108.3	144.9	0	0	0	0	0	119.3
11	G	25.4	Very low	32.9	Very low	79 Å²	79	147.7 Å²	147.7	81%	0.814	83%	0.83	S	S	*	*			trans	-79.6	-157.5	166.5	0	0	0	0	0	113.7
12	P	39.7	Very low	31.9	Very low	126 Å²	126	146.2 Å²	146.2	82%	0.818	82%	0.817	S	S	*	*			cis	-134.3	167.4	1.3	40.1	-21.2	0	0	0	117.1
13	R	35.3	Very low	32.1	Very low	226 Å²	226	139.6 Å²	139.6	85%	0.853	81%	0.814	S	S	*	*			trans	19.3	154.4	147.6	-82.7	-173.3	-166.9	-172.9	4.6	122.7
14	P	37.6	Very low	31.8	Very low	105 Å²	105	132.9 Å²	132.9	68%	0.682	81%	0.806	S	S	*	*				-146.1	147	54.7	33.7	-9.4	0	0	0	118.6
15	E	26.8	Very low	32.2	Very low	168 Å²	168	137.7 Å²	137.7	79%	0.785	81%	0.813	S	S	*	*				79.7	106.5	114.9	-67.8	174.2	-174.5	0	0	114.5
16	S	33.3	Very low	31.8	Very low	113 Å²	113	139.4 Å²	139.4	79%	0.79	82%	0.821	S	S	*	*				47	131	66.3	-60.5	0	0	0	0	113.9
17	P	32	Very low	31.6	Very low	126 Å²	126	138.8 Å²	138.8	82%	0.818	83%	0.826	S	S	*	*				-148.8	152.6	64	36.9	-16	0	0	0	117.8
18	V	35	Very low	31.8	Very low	134 Å²	134	133.9 Å²	133.9	81%	0.812	82%	0.823	S	S	*	*			trans	-97.5	147.3	146.7	-176.1	0	0	0	0	103.5
19	P	41.8	Very low	31.7	Very low	113 Å²	113	132.1 Å²	132.1	73%	0.734	82%	0.821	S	S	*	*				-163.2	171.9	59.1	41.4	-16.9	0	0	0	120.7
20	A	26.1	Very low	31.5	Very low	102 Å²	102	134.4 Å²	134.4	84%	0.843	82%	0.818	S	S	*	*			trans	61.8	125.6	143.2	0	0	0	0	0	121.8
21	G	24	Very low	31.7	Very low	70 Å²	70	136.8 Å²	136.8	72%	0.722	82%	0.815	S	S	*	*			trans	141.5	119.6	134.2	0	0	0	0	0	118
22	K	24.9	Very low	32	Very low	212 Å²	212	138.6 Å²	138.6	92%	0.922	81%	0.813	S	S	*	*			trans	88	126.2	145.9	-63.6	-179	177.4	178.3	0	119.4
23	A	33.9	Very low	31.4	Very low	104 Å²	104	138 Å²	138	86%	0.86	81%	0.811	S	S	*	*			trans	-54.5	137.6	165.7	0	0	0	0	0	112
24	S	25.1	Very low	31.3	Very low	114 Å²	114	132 Å²	132	80%	0.797	81%	0.81	S	S	*	*			trans	-140.7	133.8	153.6	-131.8	0	0	0	0	107.5	E26	S24-E26 PolarHBondContact O-N 3.3Å
25	L	37	Very low	30.8	Very low	179 Å²	179	130.5 Å²	130.5	94%	0.937	81%	0.814	S	S	*	*	P	Polyproline II helix	trans	-60.2	119	169.3	-78	105.5	0	0	0	108.4
26	E	28.9	Very low	31	Very low	194 Å²	194	133.2 Å²	133.2	91%	0.907	82%	0.817	S	S	*	*	P	Polyproline II helix	trans	-102.2	118.3	162.3	-99.1	179.3	146.4	0	0	108.4	S24	S24-E26 PolarHBondContact O-N 3.3Å
27	E	30.5	Very low	30.9	Very low	179 Å²	179	132.5 Å²	132.5	84%	0.836	82%	0.818	S	S	*	*	P	Polyproline II helix	trans	-55.9	148.9	171.2	-72.5	172.6	132.5	0	0	111.3
28	P	35.4	Very low	31	Very low	116 Å²	116	132.6 Å²	132.6	75%	0.753	82%	0.817	S	S	*	*	P	Polyproline II helix	trans	-67.3	143.5	173.1	28.6	-31.8	0	0	0	110.2
29	P	33.1	Very low	30.8	Very low	125 Å²	125	128.2 Å²	128.2	81%	0.812	80%	0.798	S	S	*	*	P	Polyproline II helix	trans	-66.5	142.2	-177.8	27.3	-32.6	0	0	0	111.2	V31	P29-V31 PolarHBondContact O-N 3.42Å
30	D	27.6	Very low	30.4	Very low	157 Å²	157	130 Å²	130	84%	0.84	81%	0.81	S	S	*	*			trans	-40.2	127.5	-177	-70.9	-56	0	0	0	114.6
31	V	32.9	Very low	30.9	Very low	130 Å²	130	128.5 Å²	128.5	79%	0.788	80%	0.804	S	S	*	*	P	Polyproline II helix	trans	-58.1	124.1	161.1	178.9	0	0	0	0	107.5	P29 S33	P29-V31 PolarHBondContact O-N 3.42Å; V31-S33 PolarHBondContact O-N 2.93Å
32	P	31	Very low	31.6	Very low	118 Å²	118	129.9 Å²	129.9	77%	0.766	81%	0.809	S	S	*	*	P	Polyproline II helix	trans	-64.3	116.8	170.3	-4.2	16.6	0	0	0	107.2	A34	P32-A34 PolarHBondContact O-N 3.14Å
33	S	28.2	Very low	32	Very low	112 Å²	112	122.8 Å²	122.8	78%	0.783	80%	0.795	S	S	*	*	P	Polyproline II helix	trans	-48.7	123.3	172.7	48.5	0	0	0	0	109.2	V31 G35	V31-S33 PolarHBondContact O-N 2.93Å; S33-G35 PolarHBondContact O-N 3.11Å
34	A	31.8	Very low	32.4	Very low	100 Å²	100	126.3 Å²	126.3	83%	0.826	79%	0.786	S	S	*	*			trans	-57.5	102	175	0	0	0	0	0	108.7	P32 R36	P32-A34 PolarHBondContact O-N 3.14Å; A34-R36 PolarHBondContact O-N 3.45Å
35	G	26.7	Very low	33.8	Very low	74 Å²	74	124.9 Å²	124.9	76%	0.763	76%	0.764	S	S	*	*			trans	-55.9	105.7	167.8	0	0	0	0	0	108.4	S33 A37	S33-G35 PolarHBondContact O-N 3.11Å; G35-A37 VanDerWaalsContact C-N 3.34Å; G35-A37 PolarHBondContact O-N 3.49Å
36	R	32.3	Very low	34.8	Very low	226 Å²	226	122.2 Å²	122.2	85%	0.853	76%	0.76	S	S	*	*			trans	-65.2	95.2	175.1	-158.6	176	-169	176.4	2.2	107	A34 T38	A34-R36 PolarHBondContact O-N 3.45Å; R36-T38 VanDerWaalsContact C-N 3.28Å; R36-T38 HydrophobicContact CG-CG2 4.45Å; R36-T38 PolarHBondContact O-N 2.93Å
37	A	30.4	Very low	36.6	Very low	98 Å²	98	113.8 Å²	113.8	81%	0.81	72%	0.722	S	S	*	*			trans	-65.3	92.2	169	0	0	0	0	0	108.4	G35 G39	G35-A37 VanDerWaalsContact C-N 3.34Å; G35-A37 PolarHBondContact O-N 3.49Å; A37-G39 VanDerWaalsContact C-N 3.27Å; A37-G39 PolarHBondContact O-N 3.45Å
38	T	34.3	Very low	39	Very low	128 Å²	128	109.1 Å²	109.1	79%	0.785	70%	0.7	S	S	*	*			trans	-77.2	80.8	169.2	45.5	0	0	0	0	108.7	R36	R36-T38 VanDerWaalsContact C-N 3.28Å; R36-T38 HydrophobicContact CG-CG2 4.45Å; R36-T38 PolarHBondContact O-N 2.93Å
39	G	30.6	Very low	41.2	Very low	41 Å²	41	104.3 Å²	104.3	42%	0.423	67%	0.669	S	S	.	*			trans	-105	156.6	161.8	0	0	0	0	0	110.5	A37 G41	A37-G39 VanDerWaalsContact C-N 3.27Å; A37-G39 PolarHBondContact O-N 3.45Å; G39-G41 PolarHBondContact O-N 3.38Å
40	P	34.4	Very low	43.5	Very low	152 Å²	152	103.8 Å²	103.8	99%	0.987	66%	0.656	S	S	*	*	T	Hydrogen-bonded Turn	trans	-74.2	76.5	-179.8	31.5	-32.7	0	0	0	110.2
41	G	36.3	Very low	46.3	Very low	69 Å²	69	98.4 Å²	98.4	71%	0.711	63%	0.629	S	S	*	*	T	Hydrogen-bonded Turn	trans	-164.7	13.7	175.6	0	0	0	0	0	111.9	G39 G43	G39-G41 PolarHBondContact O-N 3.38Å; G41-G43 PolarHBondContact O-N 2.9Å
42	A	37.8	Very low	48.6	Very low	100 Å²	100	98.3 Å²	98.3	83%	0.826	62%	0.615	S	S	*	*			trans	-79.9	65.2	-177.6	0	0	0	0	0	111.3
43	G	33.9	Very low	51.1	Low	62 Å²	62	95.7 Å²	95.7	64%	0.639	59%	0.594	S	S	*	*			trans	-132.6	69.1	161.3	0	0	0	0	0	107.3	G41 R45	G41-G43 PolarHBondContact O-N 2.9Å; G43-R45 PolarHBondContact O-N 3.19Å
44	R	42.2	Very low	53.7	Low	178 Å²	178	92.5 Å²	92.5	67%	0.672	57%	0.569	S	S	*	*			trans	-53.4	111.4	170.7	-161.3	176.7	-167	-174	2.4	106	S46 E50	R44-S46 PolarHBondContact O-N 3.11Å; R44-S46 VanDerWaalsContact O-N 3.08Å; R44-E50 IonicContact NH1-OE1 3.62Å
45	R	55.2	Low	55.9	Low	85 Å²	85	90.5 Å²	90.5	32%	0.321	56%	0.558	S	S	.	*			trans	-52.9	120.5	179.8	-86.9	177.7	177.3	173.8	-3.9	107	G43 T47 E48 D367	G43-R45 PolarHBondContact O-N 3.19Å; R45-T47 PolarHBondContact O-N 3.4Å; R45-E48 HydrophobicContact CB-CG 3.99Å; R45-E48 PolarHBondContact O-N 2.86Å; R45-E48 VanDerWaalsContact O-N 3.15Å; R45-D367 IonicContact NH1-OD1 3.25Å; R45-D367 PolarHBondContact NH1-OD1 3.12Å
46	S	57.4	Low	58.4	Low	122 Å²	122	89.3 Å²	89.3	85%	0.853	54%	0.536	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.3	-7	-179.1	55.8	0	0	0	0	113.9	R44	R44-S46 PolarHBondContact O-N 3.11Å; R44-S46 VanDerWaalsContact O-N 3.08Å
47	T	67.7	Low	60.4	Low	18 Å²	18	83.1 Å²	83.1	11%	0.11	52%	0.52	C	S	.	.	T	Hydrogen-bonded Turn	trans	-100.6	-3.9	-176.7	56.8	0	0	0	0	114.5	R45 R302 E304	R45-T47 PolarHBondContact O-N 3.4Å; T47-R302 PolarHBondContact O-N 3.44Å; T47-R302 VanDerWaalsContact O-N 3.1Å; T47-E304 HydrophobicContact CG2-CG 4.14Å; T47-E304 VanDerWaalsContact CG2-OE1 3.27Å; T47-E304 WeakPolarHBondContact CG2-OE1 3.43Å
48	E	79.9	Confident	62.7	Low	80 Å²	80	80.6 Å²	80.6	37%	0.374	49%	0.494	S	S	.	.	B	Isolated β-bridge	trans	-96.3	137.3	179.6	-61.2	-168.5	171.8	0	0	112.1	R45 W300 V301	R45-E48 HydrophobicContact CB-CG 3.99Å; R45-E48 PolarHBondContact O-N 2.86Å; R45-E48 VanDerWaalsContact O-N 3.15Å; E48-W300 WeakPolarHBondContact CA-O 3.31Å; E48-V301 HydrophobicContact CG-CG1 4.24Å; E48-V301 HydrophobicContact CG-CG2 3.92Å
49	S	81.9	Confident	64.9	Low	15 Å²	15	81.7 Å²	81.7	11%	0.105	49%	0.489	C	S	.	.	P	Polyproline II helix	trans	-66.9	150.7	176.1	62.9	0	0	0	0	112.2	V51 Y273 W300	S49-V51 PolarHBondContact O-N 3.47Å; S49-Y273 WeakPolarHBondContact OG-CD2 3.4Å; S49-Y273 WeakPolarHBondContact OG-CE2 3.41Å; S49-W300 PolarHBondContact N-O 3.26Å; S49-W300 PolarHBondContact OG-N 3.25Å; S49-W300 PolarHBondContact OG-O 2.97Å
50	E	81.6	Confident	67.3	Low	114 Å²	114	86 Å²	86	53%	0.533	50%	0.496	S	S	.	.	P	Polyproline II helix	trans	-68.2	130.8	172.6	-59.8	-163.2	136.7	0	0	112.1	R44 T272 Y273	R44-E50 IonicContact NH1-OE1 3.62Å; E50-T272 HydrophobicContact CB-CG2 4.37Å; E50-T272 WeakPolarHBondContact O-CA 3.14Å; E50-Y273 PolarHBondContact O-N 3.26Å
51	V	85	Confident	69.5	Low	45 Å²	45	81.9 Å²	81.9	27%	0.273	46%	0.461	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.1	132.4	178.6	-173.9	0	0	0	0	109.7	S49 Y273 Y298	S49-V51 PolarHBondContact O-N 3.47Å; V51-Y273 CarbonylContact C-O 3.55Å; V51-Y273 WeakPolarHBondContact CA-O 3.42Å; V51-Y298 HydrophobicContact CG1-CE1 3.98Å; V51-Y298 HydrophobicContact CG1-CE2 4.45Å
52	Y	82.6	Confident	71.7	Confident	127 Å²	127	85.8 Å²	85.8	50%	0.498	45%	0.454	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.9	121.4	166.3	175.9	-91.2	0	0	0	107.9	D54 Y273 K274 W275 Q276	Y52-D54 HydrophobicContact CE1-CB 4.44Å; Y52-Y273 PolarHBondContact N-O 3.47Å; Y52-K274 CarbonylContact O-C 3.59Å; Y52-K274 WeakPolarHBondContact O-CA 3.02Å; Y52-W275 PolarHBondContact O-N 3.05Å; Y52-Q276 HydrophobicContact CE1-CG 4.15Å
53	D	83.6	Confident	73.9	Confident	63 Å²	63	83.4 Å²	83.4	34%	0.337	43%	0.434	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.8	129.5	174	-165.9	-28	0	0	0	108.4	G55 W275 Y298	D53-G55 PolarHBondContact O-N 3.02Å; D53-G55 PolarHBondContact OD1-N 3.19Å; D53-W275 WeakPolarHBondContact CA-O 3.3Å; D53-W275 HydrophobicContact CB-CB 4.27Å; D53-Y298 VanDerWaalsContact OD2-CE2 3.3Å; D53-Y298 WeakPolarHBondContact OD2-CE2 3.48Å; D53-Y298 PolarHBondContact OD2-OH 3.14Å
54	D	82.4	Confident	76.5	Confident	46 Å²	46	83.1 Å²	83.1	25%	0.246	42%	0.416	C	S	.	.			trans	-79.1	1.6	177.3	69.2	2.9	0	0	0	113	Y52 T56 W275 Q276 G277 N280	Y52-D54 HydrophobicContact CE1-CB 4.44Å; D54-T56 PolarHBondContact O-N 2.89Å; D54-T56 VanDerWaalsContact OD1-CB 3.25Å; D54-T56 WeakPolarHBondContact OD1-CB 3.49Å; D54-T56 PolarHBondContact OD1-N 3.39Å; D54-T56 VanDerWaalsContact OD1-N 3.15Å; D54-T56 PolarHBondContact OD1-OG1 3.27Å; D54-T56 PolarHBondContact OD2-OG1 2.92Å; D54-W275 PolarHBondContact N-O 2.82Å; D54-W275 VanDerWaalsContact N-O 3.09Å; D54-Q276 WeakPolarHBondContact OD2-CA 3.04Å; D54-G277 PolarHBondContact OD1-N 2.7Å; D54-G277 PolarHBondContact OD2-N 3.23Å; D54-N280 PolarHBondContact OD2-ND2 3.48Å
55	G	77.9	Confident	78.8	Confident	58 Å²	58	77.2 Å²	77.2	60%	0.598	40%	0.4	S	S	*	.			trans	75.1	13	175.3	0	0	0	0	0	113.4	D53 N57	D53-G55 PolarHBondContact O-N 3.02Å; D53-G55 PolarHBondContact OD1-N 3.19Å; G55-N57 PolarHBondContact O-N 3.28Å
56	T	79.1	Confident	80.5	Confident	49 Å²	49	79.6 Å²	79.6	30%	0.301	42%	0.418	S	S	.	.			trans	-67.5	95	-176.7	-54.3	0	0	0	0	111.4	D54 T58	D54-T56 PolarHBondContact O-N 2.89Å; D54-T56 VanDerWaalsContact OD1-CB 3.25Å; D54-T56 WeakPolarHBondContact OD1-CB 3.49Å; D54-T56 PolarHBondContact OD1-N 3.39Å; D54-T56 VanDerWaalsContact OD1-N 3.15Å; D54-T56 PolarHBondContact OD1-OG1 3.27Å; D54-T56 PolarHBondContact OD2-OG1 2.92Å; T56-T58 HydrophobicContact CG2-CG2 3.71Å; T56-T58 PolarHBondContact O-N 3.46Å
57	N	74	Confident	82.1	Confident	95 Å²	95	77.5 Å²	77.5	51%	0.508	40%	0.401	S	S	.	.			trans	-93.5	85.5	172.7	-169.1	-38.7	0	0	0	110.6	G55 R62	G55-N57 PolarHBondContact O-N 3.28Å; N57-R62 WeakPolarHBondContact OD1-CG 3.49Å; N57-R62 PolarHBondContact OD1-NE 2.89Å
58	T	80	Confident	83.2	Confident	46 Å²	46	78.6 Å²	78.6	28%	0.282	41%	0.407	S	S	.	.			trans	-73.3	161.6	175.5	62.3	0	0	0	0	112.3	T56 F60 W61	T56-T58 HydrophobicContact CG2-CG2 3.71Å; T56-T58 PolarHBondContact O-N 3.46Å; T58-F60 PolarHBondContact O-N 3.43Å; T58-W61 PolarHBondContact O-N 3.19Å
59	F	80.1	Confident	83.7	Confident	151 Å²	151	79.7 Å²	79.7	66%	0.662	42%	0.415	S	S	*	.	G	3₁₀ helix	trans	-41.7	-45.3	170.3	-177.4	-94.9	0	0	0	112.7	W61 R62 H64	F59-W61 PolarHBondContact O-N 2.96Å; F59-R62 PolarHBondContact O-N 2.84Å; F59-H64 AromaticContact CD1-CE1 3.65Å; F59-H64 AromaticContact CD1-NE2 3.32Å; F59-H64 VanDerWaalsContact CD1-NE2 3.32Å; F59-H64 WeakPolarHBondContact CD1-NE2 3.28Å; F59-H64 AromaticContact CD2-CE1 3.28Å; F59-H64 WeakPolarHBondContact CD2-CE1 2.97Å; F59-H64 AromaticContact CD2-NE2 3.87Å; F59-H64 AromaticContact CE1-CD2 3.77Å; F59-H64 AromaticContact CE1-CE1 3.44Å; F59-H64 VanDerWaalsContact CE1-CE1 3.44Å; F59-H64 WeakPolarHBondContact CE1-CE1 3.33Å; F59-H64 AromaticContact CE1-NE2 3.11Å; F59-H64 WeakPolarHBondContact CE1-NE2 3.36Å; F59-H64 AromaticContact CE2-CE1 3.05Å; F59-H64 WeakPolarHBondContact CE2-CE1 3.48Å; F59-H64 AromaticContact CE2-ND1 3.54Å; F59-H64 AromaticContact CE2-NE2 3.69Å; F59-H64 AromaticContact CG-CE1 3.57Å; F59-H64 AromaticContact CG-NE2 3.7Å; F59-H64 AromaticContact CZ-CD2 3.84Å; F59-H64 AromaticContact CZ-CE1 3.14Å; F59-H64 WeakPolarHBondContact CZ-CE1 3.3Å; F59-H64 AromaticContact CZ-CG 3.97Å; F59-H64 AromaticContact CZ-ND1 3.54Å; F59-H64 AromaticContact CZ-NE2 3.31Å; F59-H64 VanDerWaalsContact CZ-NE2 3.31Å; F59-H64 WeakPolarHBondContact CZ-NE2 3.14Å; F59-H64 PolarHBondContact O-CE1 2.83Å; F59-H64 PolarHBondContact O-NE2 3.2Å
60	F	80.8	Confident	84.3	Confident	131 Å²	131	85.7 Å²	85.7	58%	0.575	44%	0.439	S	S	*	.	G	3₁₀ helix	trans	-50.8	-32	177.6	-179.4	-101.4	0	0	0	115.3	T58 H121	T58-F60 PolarHBondContact O-N 3.43Å; F60-H121 AromaticContact CE1-CD2 3.48Å; F60-H121 VanDerWaalsContact CE1-CD2 3.48Å; F60-H121 WeakPolarHBondContact CE1-CD2 3.5Å; F60-H121 AromaticContact CZ-CD2 3.96Å; F60-H121 PolarHBondContact O-NE2 3.42Å
61	W	80.3	Confident	84.9	Confident	66 Å²	66	84.9 Å²	84.9	25%	0.25	44%	0.438	C	S	.	.	G	3₁₀ helix	trans	-86.4	-7.3	-176.7	-67.4	106.4	0	0	0	113.9	T58 F59 H121 P122	T58-W61 PolarHBondContact O-N 3.19Å; F59-W61 PolarHBondContact O-N 2.96Å; W61-H121 AromaticContact CE3-CD2 3.68Å; W61-H121 AromaticContact CE3-NE2 3.85Å; W61-H121 AromaticContact CZ3-CD2 3.76Å; W61-P122 HydrophobicContact CE3-CG 4.44Å; W61-P122 HydrophobicContact CZ3-CG 4.49Å
62	R	82.4	Confident	85.2	Confident	150 Å²	150	84.5 Å²	84.5	57%	0.566	43%	0.434	S	S	*	.	S	Bend	trans	-96.2	141.6	-176.2	-59.6	-175.1	-174.9	-174.8	1.4	110.1	N57 F59 H64	N57-R62 WeakPolarHBondContact OD1-CG 3.49Å; N57-R62 PolarHBondContact OD1-NE 2.89Å; F59-R62 PolarHBondContact O-N 2.84Å; R62-H64 PolarHBondContact O-CD2 2.61Å; R62-H64 PolarHBondContact O-N 3.22Å; R62-H64 PolarHBondContact O-NE2 2.84Å
63	A	84.3	Confident	85.6	Confident	50 Å²	50	82.4 Å²	82.4	41%	0.413	44%	0.435	S	S	.	.			trans	-73.4	119.2	170.5	0	0	0	0	0	109.8	T65	A63-T65 HydrophobicContact CB-CG2 4.41Å; A63-T65 PolarHBondContact O-N 3.06Å
64	H	87.8	Confident	86.1	Confident	56 Å²	56	82.3 Å²	82.3	26%	0.259	44%	0.438	S	S	.	.			trans	-90.4	67.8	178	-58.7	-60.9	0	0	0	111.5	F59 R62 L66 T67 V68	F59-H64 AromaticContact CD1-CE1 3.65Å; F59-H64 AromaticContact CD1-NE2 3.32Å; F59-H64 VanDerWaalsContact CD1-NE2 3.32Å; F59-H64 WeakPolarHBondContact CD1-NE2 3.28Å; F59-H64 AromaticContact CD2-CE1 3.28Å; F59-H64 WeakPolarHBondContact CD2-CE1 2.97Å; F59-H64 AromaticContact CD2-NE2 3.87Å; F59-H64 AromaticContact CE1-CD2 3.77Å; F59-H64 AromaticContact CE1-CE1 3.44Å; F59-H64 VanDerWaalsContact CE1-CE1 3.44Å; F59-H64 WeakPolarHBondContact CE1-CE1 3.33Å; F59-H64 AromaticContact CE1-NE2 3.11Å; F59-H64 WeakPolarHBondContact CE1-NE2 3.36Å; F59-H64 AromaticContact CE2-CE1 3.05Å; F59-H64 WeakPolarHBondContact CE2-CE1 3.48Å; F59-H64 AromaticContact CE2-ND1 3.54Å; F59-H64 AromaticContact CE2-NE2 3.69Å; F59-H64 AromaticContact CG-CE1 3.57Å; F59-H64 AromaticContact CG-NE2 3.7Å; F59-H64 AromaticContact CZ-CD2 3.84Å; F59-H64 AromaticContact CZ-CE1 3.14Å; F59-H64 WeakPolarHBondContact CZ-CE1 3.3Å; F59-H64 AromaticContact CZ-CG 3.97Å; F59-H64 AromaticContact CZ-ND1 3.54Å; F59-H64 AromaticContact CZ-NE2 3.31Å; F59-H64 VanDerWaalsContact CZ-NE2 3.31Å; F59-H64 WeakPolarHBondContact CZ-NE2 3.14Å; F59-H64 PolarHBondContact O-CE1 2.83Å; F59-H64 PolarHBondContact O-NE2 3.2Å; R62-H64 PolarHBondContact O-CD2 2.61Å; R62-H64 PolarHBondContact O-N 3.22Å; R62-H64 PolarHBondContact O-NE2 2.84Å; H64-L66 PolarHBondContact O-N 3.3Å; H64-T67 PolarHBondContact O-N 3.13Å; H64-V68 VanDerWaalsContact O-CG2 3.32Å; H64-V68 WeakPolarHBondContact O-CG2 3.11Å; H64-V68 PolarHBondContact O-N 3.01Å
65	T	90.6	Very high	86.5	Confident	55 Å²	55	83.8 Å²	83.8	34%	0.337	45%	0.449	S	S	.	.	H	α-helix	trans	-57.6	-46	-173.1	55.1	0	0	0	0	113.2	A63 V68 L69	A63-T65 HydrophobicContact CB-CG2 4.41Å; A63-T65 PolarHBondContact O-N 3.06Å; T65-V68 PolarHBondContact O-N 3.45Å; T65-L69 WeakPolarHBondContact O-CB 3.44Å; T65-L69 PolarHBondContact O-N 2.91Å
66	L	91.1	Very high	87.1	Confident	135 Å²	135	85.4 Å²	85.4	71%	0.707	44%	0.443	S	S	*	.	H	α-helix	trans	-66.5	-39.6	179.6	-66.6	178.9	0	0	0	112.6	H64 L69 F70	H64-L66 PolarHBondContact O-N 3.3Å; L66-L69 PolarHBondContact O-N 3.4Å; L66-F70 WeakPolarHBondContact O-CB 3.19Å; L66-F70 PolarHBondContact O-N 2.64Å
67	T	90.2	Very high	87.7	Confident	78 Å²	78	84.4 Å²	84.4	48%	0.479	44%	0.442	S	S	.	.	H	α-helix	trans	-64.4	-44.6	177.3	-51.8	0	0	0	0	110.8	H64 F70 I71	H64-T67 PolarHBondContact O-N 3.13Å; T67-F70 PolarHBondContact O-N 2.86Å; T67-I71 HydrophobicContact CG2-CD1 4.09Å; T67-I71 WeakPolarHBondContact O-CG1 3.14Å; T67-I71 PolarHBondContact O-N 2.75Å
68	V	91.3	Very high	88.5	Confident	41 Å²	41	86.2 Å²	86.2	25%	0.248	44%	0.443	C	S	.	.	H	α-helix	trans	-63.6	-44.3	176.9	173	0	0	0	0	110.5	H64 T65 F70 I71 L72 C106 T110	H64-V68 VanDerWaalsContact O-CG2 3.32Å; H64-V68 WeakPolarHBondContact O-CG2 3.11Å; H64-V68 PolarHBondContact O-N 3.01Å; T65-V68 PolarHBondContact O-N 3.45Å; V68-F70 VanDerWaalsContact C-N 3.34Å; V68-F70 PolarHBondContact O-N 3.37Å; V68-I71 PolarHBondContact O-N 2.82Å; V68-L72 HydrophobicContact CG1-CD1 3.9Å; V68-L72 HydrophobicContact CG1-CG 4.29Å; V68-L72 WeakPolarHBondContact O-CB 3.31Å; V68-L72 VanDerWaalsContact O-CG 3.29Å; V68-L72 WeakPolarHBondContact O-CG 3.25Å; V68-L72 PolarHBondContact O-N 2.86Å; V68-C106 HydrophobicContact CG1-CB 4.2Å; V68-T110 HydrophobicContact CB-CG2 4.14Å; V68-T110 HydrophobicContact CG1-CG2 4.09Å; V68-T110 HydrophobicContact CG2-CG2 3.86Å
69	L	91.6	Very high	89	Confident	103 Å²	103	86.4 Å²	86.4	54%	0.539	44%	0.444	S	S	.	.	H	α-helix	trans	-59.3	-44.1	176.3	179.4	62.8	0	0	0	112.1	T65 L66 L72 T73	T65-L69 WeakPolarHBondContact O-CB 3.44Å; T65-L69 PolarHBondContact O-N 2.91Å; L66-L69 PolarHBondContact O-N 3.4Å; L69-L72 PolarHBondContact O-N 3.37Å; L69-T73 WeakPolarHBondContact O-CB 3.48Å; L69-T73 PolarHBondContact O-N 2.94Å; L69-T73 PolarHBondContact O-OG1 3.43Å
70	F	93.9	Very high	89.4	Confident	141 Å²	141	84.4 Å²	84.4	62%	0.618	44%	0.444	S	S	*	.	H	α-helix	trans	-60.8	-50.2	177	178.2	-99.5	0	0	0	111.2	L66 T67 V68 L72 T73 C74	L66-F70 WeakPolarHBondContact O-CB 3.19Å; L66-F70 PolarHBondContact O-N 2.64Å; T67-F70 PolarHBondContact O-N 2.86Å; V68-F70 VanDerWaalsContact C-N 3.34Å; V68-F70 PolarHBondContact O-N 3.37Å; F70-L72 PolarHBondContact O-N 2.91Å; F70-T73 PolarHBondContact O-N 3.15Å; F70-C74 VanDerWaalsContact CZ-SG 3.51Å; F70-C74 WeakPolarHBondContact O-CB 3.32Å; F70-C74 PolarHBondContact O-N 3.02Å; F70-C74 PolarHBondContact O-SG 3.05Å; F70-C74 VanDerWaalsContact O-SG 3.35Å
71	I	93.1	Very high	89.9	Confident	96 Å²	96	85 Å²	85	49%	0.492	45%	0.452	S	S	.	.	H	α-helix	trans	-60.4	-45.7	179.1	-67.9	168.3	0	0	0	111.2	T67 V68 T73 C74 T75	T67-I71 HydrophobicContact CG2-CD1 4.09Å; T67-I71 WeakPolarHBondContact O-CG1 3.14Å; T67-I71 PolarHBondContact O-N 2.75Å; V68-I71 PolarHBondContact O-N 2.82Å; I71-T73 PolarHBondContact O-N 3.09Å; I71-C74 PolarHBondContact O-N 3.12Å; I71-T75 WeakPolarHBondContact O-CB 3.05Å; I71-T75 PolarHBondContact O-N 3.36Å; I71-T75 PolarHBondContact O-OG1 3.47Å
72	L	91.6	Very high	90.4	Very high	38 Å²	38	87.8 Å²	87.8	20%	0.199	47%	0.472	C	S	.	.	H	α-helix	trans	-60.2	-45.9	177.6	-72.8	174.5	0	0	0	111.2	V68 L69 F70 T75 L76 V103 C106	V68-L72 HydrophobicContact CG1-CD1 3.9Å; V68-L72 HydrophobicContact CG1-CG 4.29Å; V68-L72 WeakPolarHBondContact O-CB 3.31Å; V68-L72 VanDerWaalsContact O-CG 3.29Å; V68-L72 WeakPolarHBondContact O-CG 3.25Å; V68-L72 PolarHBondContact O-N 2.86Å; L69-L72 PolarHBondContact O-N 3.37Å; F70-L72 PolarHBondContact O-N 2.91Å; L72-T75 PolarHBondContact O-N 3.02Å; L72-L76 WeakPolarHBondContact O-CG 3.28Å; L72-L76 PolarHBondContact O-N 2.95Å; L72-V103 HydrophobicContact CD2-CG2 4.3Å; L72-C106 HydrophobicContact CD1-CB 3.94Å; L72-C106 HydrophobicContact CD2-CB 4.21Å
73	T	91.7	Very high	90.7	Very high	83 Å²	83	83.9 Å²	83.9	51%	0.509	46%	0.46	S	S	.	.	H	α-helix	trans	-64.5	-44.4	179.4	-52.8	0	0	0	0	111.5	L69 F70 I71 T75 L76 G77	L69-T73 WeakPolarHBondContact O-CB 3.48Å; L69-T73 PolarHBondContact O-N 2.94Å; L69-T73 PolarHBondContact O-OG1 3.43Å; F70-T73 PolarHBondContact O-N 3.15Å; I71-T73 PolarHBondContact O-N 3.09Å; T73-T75 VanDerWaalsContact C-N 3.33Å; T73-T75 PolarHBondContact O-N 3.06Å; T73-L76 PolarHBondContact O-N 3.19Å; T73-G77 PolarHBondContact O-N 2.7Å
74	C	93.5	Very high	90.8	Very high	61 Å²	61	90.2 Å²	90.2	41%	0.412	48%	0.481	S	S	.	.	H	α-helix	trans	-62.9	-39.3	175.4	-71	0	0	0	0	112.2	F70 I71 G77 Y78	F70-C74 VanDerWaalsContact CZ-SG 3.51Å; F70-C74 WeakPolarHBondContact O-CB 3.32Å; F70-C74 PolarHBondContact O-N 3.02Å; F70-C74 PolarHBondContact O-SG 3.05Å; F70-C74 VanDerWaalsContact O-SG 3.35Å; I71-C74 PolarHBondContact O-N 3.12Å; C74-G77 PolarHBondContact O-N 3.35Å; C74-Y78 WeakPolarHBondContact O-CB 3.47Å; C74-Y78 PolarHBondContact O-N 3.33Å
75	T	90.9	Very high	90.7	Very high	76 Å²	76	92.3 Å²	92.3	47%	0.466	50%	0.498	S	S	.	.	H	α-helix	trans	-65.8	-44.6	178.4	-55	0	0	0	0	110.9	I71 L72 T73 G77 Y78 V79	I71-T75 WeakPolarHBondContact O-CB 3.05Å; I71-T75 PolarHBondContact O-N 3.36Å; I71-T75 PolarHBondContact O-OG1 3.47Å; L72-T75 PolarHBondContact O-N 3.02Å; T73-T75 VanDerWaalsContact C-N 3.33Å; T73-T75 PolarHBondContact O-N 3.06Å; T75-G77 VanDerWaalsContact C-N 3.33Å; T75-G77 PolarHBondContact O-N 3.4Å; T75-Y78 PolarHBondContact O-N 2.92Å; T75-V79 WeakPolarHBondContact O-CG2 3.26Å; T75-V79 PolarHBondContact O-N 3.48Å
76	L	90.6	Very high	90.5	Very high	93 Å²	93	92.4 Å²	92.4	49%	0.487	50%	0.5	S	S	.	.	H	α-helix	trans	-63.2	-40.5	174.2	-69	175.4	0	0	0	111.7	L72 T73 V79 T80	L72-L76 WeakPolarHBondContact O-CG 3.28Å; L72-L76 PolarHBondContact O-N 2.95Å; T73-L76 PolarHBondContact O-N 3.19Å; L76-V79 PolarHBondContact O-N 3.02Å; L76-T80 WeakPolarHBondContact O-CB 3.47Å; L76-T80 PolarHBondContact O-N 3.45Å; L76-T80 PolarHBondContact O-OG1 3.15Å
77	G	91.7	Very high	90.4	Very high	27 Å²	27	95.7 Å²	95.7	28%	0.278	51%	0.511	S	S	.	.	H	α-helix	trans	-60.6	-44.4	173.6	0	0	0	0	0	112.6	T73 C74 T75 T80 L81	T73-G77 PolarHBondContact O-N 2.7Å; C74-G77 PolarHBondContact O-N 3.35Å; T75-G77 VanDerWaalsContact C-N 3.33Å; T75-G77 PolarHBondContact O-N 3.4Å; G77-T80 PolarHBondContact O-N 2.93Å; G77-L81 VanDerWaalsContact O-CB 3.25Å; G77-L81 WeakPolarHBondContact O-CB 3.5Å; G77-L81 VanDerWaalsContact O-CG 3.27Å; G77-L81 WeakPolarHBondContact O-CG 2.93Å; G77-L81 PolarHBondContact O-N 2.88Å
78	Y	92.1	Very high	90.4	Very high	134 Å²	134	95.7 Å²	95.7	53%	0.525	51%	0.509	S	S	.	.	H	α-helix	trans	-59.3	-52.8	175.4	175.1	-88.7	0	0	0	111.4	C74 T75 T80 L81 L82 E83	C74-Y78 WeakPolarHBondContact O-CB 3.47Å; C74-Y78 PolarHBondContact O-N 3.33Å; T75-Y78 PolarHBondContact O-N 2.92Å; Y78-T80 PolarHBondContact O-N 3.4Å; Y78-L81 PolarHBondContact O-N 3.44Å; Y78-L82 HydrophobicContact CD2-CB 4.08Å; Y78-L82 HydrophobicContact CD2-CD1 3.48Å; Y78-L82 VanDerWaalsContact CD2-CD1 3.48Å; Y78-L82 HydrophobicContact CD2-CG 4.35Å; Y78-L82 HydrophobicContact CE2-CB 4.04Å; Y78-L82 HydrophobicContact CE2-CD1 3.82Å; Y78-L82 HydrophobicContact CG-CD1 4.39Å; Y78-L82 WeakPolarHBondContact O-CA 3.45Å; Y78-L82 WeakPolarHBondContact O-CB 3.35Å; Y78-L82 PolarHBondContact O-N 3.37Å; Y78-E83 PolarHBondContact O-N 3.43Å
79	V	90.3	Very high	90.3	Very high	50 Å²	50	99.2 Å²	99.2	30%	0.303	53%	0.53	S	S	.	.	H	α-helix	trans	-58.9	-37.5	179.7	167.3	0	0	0	0	111.6	T75 L76	T75-V79 WeakPolarHBondContact O-CG2 3.26Å; T75-V79 PolarHBondContact O-N 3.48Å; L76-V79 PolarHBondContact O-N 3.02Å
80	T	87.6	Confident	90.1	Very high	109 Å²	109	96.6 Å²	96.6	67%	0.669	52%	0.523	S	S	*	.	H	α-helix	trans	-78	-38	-177.4	-53.6	0	0	0	0	112.7	L76 G77 Y78	L76-T80 WeakPolarHBondContact O-CB 3.47Å; L76-T80 PolarHBondContact O-N 3.45Å; L76-T80 PolarHBondContact O-OG1 3.15Å; G77-T80 PolarHBondContact O-N 2.93Å; Y78-T80 PolarHBondContact O-N 3.4Å
81	L	91.6	Very high	89.8	Confident	142 Å²	142	95.2 Å²	95.2	74%	0.743	52%	0.515	S	S	*	.	H	α-helix	trans	-101	-24.7	-168.9	-61.5	176.2	0	0	0	114	G77 Y78	G77-L81 VanDerWaalsContact O-CB 3.25Å; G77-L81 WeakPolarHBondContact O-CB 3.5Å; G77-L81 VanDerWaalsContact O-CG 3.27Å; G77-L81 WeakPolarHBondContact O-CG 2.93Å; G77-L81 PolarHBondContact O-N 2.88Å; Y78-L81 PolarHBondContact O-N 3.44Å
82	L	90.4	Very high	89.7	Confident	125 Å²	125	92.9 Å²	92.9	65%	0.654	50%	0.503	S	S	*	.	T	Hydrogen-bonded Turn	trans	-122.1	-16.1	-168.6	-62	175.3	0	0	0	113.8	Y78	Y78-L82 HydrophobicContact CD2-CB 4.08Å; Y78-L82 HydrophobicContact CD2-CD1 3.48Å; Y78-L82 VanDerWaalsContact CD2-CD1 3.48Å; Y78-L82 HydrophobicContact CD2-CG 4.35Å; Y78-L82 HydrophobicContact CE2-CB 4.04Å; Y78-L82 HydrophobicContact CE2-CD1 3.82Å; Y78-L82 HydrophobicContact CG-CD1 4.39Å; Y78-L82 WeakPolarHBondContact O-CA 3.45Å; Y78-L82 WeakPolarHBondContact O-CB 3.35Å; Y78-L82 PolarHBondContact O-N 3.37Å
83	E	87.9	Confident	89.6	Confident	69 Å²	69	94.8 Å²	94.8	32%	0.322	52%	0.516	S	S	.	.	P	Polyproline II helix	trans	-103.7	122	-178.1	-158.9	175.8	157.9	0	0	111.5	Y78 R95	Y78-E83 PolarHBondContact O-N 3.43Å; E83-R95 VanDerWaalsContact CD-NH1 3.31Å; E83-R95 IonicContact OE1-CZ 3.46Å; E83-R95 IonicContact OE1-NH1 3.33Å; E83-R95 PolarHBondContact OE1-NH1 3.33Å; E83-R95 IonicContact OE1-NH2 2.7Å; E83-R95 PolarHBondContact OE1-NH2 2.73Å; E83-R95 VanDerWaalsContact OE1-NH2 3.12Å; E83-R95 IonicContact OE2-CZ 2.59Å; E83-R95 IonicContact OE2-NH1 2.68Å; E83-R95 IonicContact OE2-NH2 3.22Å; E83-R95 PolarHBondContact OE2-NH2 2.77Å
84	E	86.3	Confident	89.4	Confident	182 Å²	182	96 Å²	96	85%	0.85	52%	0.515	S	S	*	.	P	Polyproline II helix	trans	-72	129.7	174.6	-66.3	-172.9	174.5	0	0	110.3	P86	E84-P86 WeakPolarHBondContact O-CD 3.42Å
85	T	85.8	Confident	89.3	Confident	100 Å²	100	96 Å²	96	61%	0.613	51%	0.506	S	S	*	.	P	Polyproline II helix	trans	-80.7	119.2	-179.5	-58.2	0	0	0	0	110.3	N92	T85-N92 WeakPolarHBondContact CG2-ND2 3.42Å
86	P	88.1	Confident	89.3	Confident	58 Å²	58	94 Å²	94	38%	0.377	50%	0.501	S	S	.	.	P	Polyproline II helix	trans	-62.4	151	176.3	-21.8	33.9	0	0	0	112.2	E84 D88 Y91 N92	E84-P86 WeakPolarHBondContact O-CD 3.42Å; P86-D88 PolarHBondContact O-N 2.85Å; P86-Y91 HydrophobicContact CG-CD1 4.22Å; P86-Y91 HydrophobicContact CG-CE1 4.07Å; P86-N92 PolarHBondContact O-ND2 3.24Å
87	Q	88.3	Confident	89.4	Confident	203 Å²	203	93.9 Å²	93.9	95%	0.949	50%	0.5	S	S	*	.	S	Bend	trans	-81.1	52.3	174.4	-65.4	-67.7	-26.6	0	0	111.7
88	D	90.6	Very high	89.4	Confident	79 Å²	79	96.1 Å²	96.1	42%	0.422	51%	0.508	S	S	.	.			trans	-130.9	106	175.5	179.4	-12	0	0	0	109.7	P86 A90 Y91 N92	P86-D88 PolarHBondContact O-N 2.85Å; D88-A90 VanDerWaalsContact C-N 3.33Å; D88-A90 PolarHBondContact O-N 3.45Å; D88-A90 WeakPolarHBondContact OD1-CB 3.34Å; D88-A90 PolarHBondContact OD1-N 3.45Å; D88-Y91 VanDerWaalsContact CG-CB 3.46Å; D88-Y91 PolarHBondContact O-N 3.47Å; D88-Y91 PolarHBondContact OD1-N 2.87Å; D88-Y91 WeakPolarHBondContact OD2-CB 3.14Å; D88-N92 WeakPolarHBondContact O-CB 3.39Å; D88-N92 PolarHBondContact O-N 3.47Å; D88-N92 PolarHBondContact O-ND2 3.27Å; D88-N92 VanDerWaalsContact O-ND2 3.1Å
89	T	89.6	Confident	89.4	Confident	114 Å²	114	91.7 Å²	91.7	70%	0.699	50%	0.499	S	S	*	.	H	α-helix	trans	-62.4	-38.5	-179.1	-51.1	0	0	0	0	112.5	T93	T89-T93 VanDerWaalsContact O-CB 3.28Å; T89-T93 WeakPolarHBondContact O-CB 3.46Å; T89-T93 PolarHBondContact O-N 3.15Å; T89-T93 PolarHBondContact O-OG1 2.7Å
90	A	86.6	Confident	89.6	Confident	48 Å²	48	93.3 Å²	93.3	40%	0.397	51%	0.512	S	S	.	.	H	α-helix	trans	-69.6	-44.6	-177.7	0	0	0	0	0	110.4	D88 T93 K94 Y156	D88-A90 VanDerWaalsContact C-N 3.33Å; D88-A90 PolarHBondContact O-N 3.45Å; D88-A90 WeakPolarHBondContact OD1-CB 3.34Å; D88-A90 PolarHBondContact OD1-N 3.45Å; A90-T93 PolarHBondContact O-N 2.92Å; A90-K94 WeakPolarHBondContact O-CB 3.31Å; A90-K94 PolarHBondContact O-N 2.72Å; A90-Y156 HydrophobicContact CB-CE1 4.5Å
91	Y	87.4	Confident	90	Very high	113 Å²	113	91 Å²	91	44%	0.443	50%	0.495	S	S	.	.	H	α-helix	trans	-60.3	-50	174.3	176.9	-97.7	0	0	0	111.9	P86 D88 T93 K94 R95	P86-Y91 HydrophobicContact CG-CD1 4.22Å; P86-Y91 HydrophobicContact CG-CE1 4.07Å; D88-Y91 VanDerWaalsContact CG-CB 3.46Å; D88-Y91 PolarHBondContact O-N 3.47Å; D88-Y91 PolarHBondContact OD1-N 2.87Å; D88-Y91 WeakPolarHBondContact OD2-CB 3.14Å; Y91-T93 VanDerWaalsContact C-N 3.32Å; Y91-T93 PolarHBondContact O-N 2.66Å; Y91-K94 PolarHBondContact O-N 2.99Å; Y91-R95 WeakPolarHBondContact O-CB 3.39Å; Y91-R95 PolarHBondContact O-N 3.46Å
92	N	90.9	Very high	90.1	Very high	47 Å²	47	89 Å²	89	25%	0.251	48%	0.484	S	S	.	.	H	α-helix	trans	-62.2	-39.5	-179.1	-69.9	-24.5	0	0	0	112	T85 P86 D88 R95 G96	T85-N92 WeakPolarHBondContact CG2-ND2 3.42Å; P86-N92 PolarHBondContact O-ND2 3.24Å; D88-N92 WeakPolarHBondContact O-CB 3.39Å; D88-N92 PolarHBondContact O-N 3.47Å; D88-N92 PolarHBondContact O-ND2 3.27Å; D88-N92 VanDerWaalsContact O-ND2 3.1Å; N92-R95 PolarHBondContact O-N 3.3Å; N92-G96 PolarHBondContact O-N 3.34Å
93	T	90.1	Very high	90.2	Very high	77 Å²	77	85.7 Å²	85.7	47%	0.472	47%	0.469	S	S	.	.	H	α-helix	trans	-64.3	-48.6	176.2	-58.2	0	0	0	0	111	T89 A90 Y91 R95 G96 I97	T89-T93 VanDerWaalsContact O-CB 3.28Å; T89-T93 WeakPolarHBondContact O-CB 3.46Å; T89-T93 PolarHBondContact O-N 3.15Å; T89-T93 PolarHBondContact O-OG1 2.7Å; A90-T93 PolarHBondContact O-N 2.92Å; Y91-T93 VanDerWaalsContact C-N 3.32Å; Y91-T93 PolarHBondContact O-N 2.66Å; T93-R95 VanDerWaalsContact C-N 3.32Å; T93-R95 PolarHBondContact O-N 2.88Å; T93-G96 PolarHBondContact O-N 2.83Å; T93-I97 HydrophobicContact CG2-CD1 3.97Å; T93-I97 WeakPolarHBondContact O-CG1 3.45Å; T93-I97 PolarHBondContact O-N 3.31Å
94	K	87.8	Confident	90.5	Very high	108 Å²	108	86 Å²	86	47%	0.47	47%	0.47	S	S	.	.	H	α-helix	trans	-57.8	-46.7	177.5	-180	170.2	-178.6	160.4	0	111.2	A90 Y91 I97 V98 Y156	A90-K94 WeakPolarHBondContact O-CB 3.31Å; A90-K94 PolarHBondContact O-N 2.72Å; Y91-K94 PolarHBondContact O-N 2.99Å; K94-I97 PolarHBondContact O-N 3.5Å; K94-V98 VanDerWaalsContact O-CG2 3.3Å; K94-V98 WeakPolarHBondContact O-CG2 3.44Å; K94-V98 PolarHBondContact O-N 3.4Å; K94-Y156 PolarHBondContact NZ-O 3.5Å
95	R	89.7	Confident	91	Very high	63 Å²	63	78.4 Å²	78.4	24%	0.238	44%	0.435	C	S	.	.	H	α-helix	trans	-62.3	-44.4	178.2	-178	-175.3	161.1	167.2	7.6	112.1	E83 Y91 N92 T93 V98 A99	E83-R95 VanDerWaalsContact CD-NH1 3.31Å; E83-R95 IonicContact OE1-CZ 3.46Å; E83-R95 IonicContact OE1-NH1 3.33Å; E83-R95 PolarHBondContact OE1-NH1 3.33Å; E83-R95 IonicContact OE1-NH2 2.7Å; E83-R95 PolarHBondContact OE1-NH2 2.73Å; E83-R95 VanDerWaalsContact OE1-NH2 3.12Å; E83-R95 IonicContact OE2-CZ 2.59Å; E83-R95 IonicContact OE2-NH1 2.68Å; E83-R95 IonicContact OE2-NH2 3.22Å; E83-R95 PolarHBondContact OE2-NH2 2.77Å; Y91-R95 WeakPolarHBondContact O-CB 3.39Å; Y91-R95 PolarHBondContact O-N 3.46Å; N92-R95 PolarHBondContact O-N 3.3Å; T93-R95 VanDerWaalsContact C-N 3.32Å; T93-R95 PolarHBondContact O-N 2.88Å; R95-V98 PolarHBondContact O-N 2.87Å; R95-A99 WeakPolarHBondContact O-CB 3.35Å; R95-A99 PolarHBondContact O-N 3.48Å
96	G	92.2	Very high	91.4	Very high	34 Å²	34	76 Å²	76	35%	0.351	42%	0.422	S	S	.	.	H	α-helix	trans	-59.2	-48	176.8	0	0	0	0	0	112.3	N92 T93 V98 A99 S100	N92-G96 PolarHBondContact O-N 3.34Å; T93-G96 PolarHBondContact O-N 2.83Å; G96-V98 PolarHBondContact O-N 3.44Å; G96-A99 PolarHBondContact O-N 2.91Å; G96-S100 PolarHBondContact O-N 3.33Å; G96-S100 PolarHBondContact O-OG 3.35Å; G96-S100 VanDerWaalsContact O-OG 3.09Å
97	I	92.3	Very high	91.6	Very high	90 Å²	90	79 Å²	79	46%	0.462	43%	0.429	S	S	.	.	H	α-helix	trans	-60	-48.1	177.1	-67.2	168.3	0	0	0	111	T93 K94 A99 S100 I101	T93-I97 HydrophobicContact CG2-CD1 3.97Å; T93-I97 WeakPolarHBondContact O-CG1 3.45Å; T93-I97 PolarHBondContact O-N 3.31Å; K94-I97 PolarHBondContact O-N 3.5Å; I97-A99 VanDerWaalsContact C-N 3.33Å; I97-A99 PolarHBondContact O-N 3.48Å; I97-S100 PolarHBondContact O-N 3.33Å; I97-I101 HydrophobicContact CG2-CD1 3.86Å; I97-I101 WeakPolarHBondContact O-CG1 3.13Å; I97-I101 PolarHBondContact O-N 3.2Å
98	V	91.6	Very high	91.9	Very high	74 Å²	74	69.6 Å²	69.6	45%	0.448	39%	0.387	S	S	.	.	H	α-helix	trans	-60	-44.8	178.1	170.8	0	0	0	0	110.8	K94 R95 G96 S100 I101 L102	K94-V98 VanDerWaalsContact O-CG2 3.3Å; K94-V98 WeakPolarHBondContact O-CG2 3.44Å; K94-V98 PolarHBondContact O-N 3.4Å; R95-V98 PolarHBondContact O-N 2.87Å; G96-V98 PolarHBondContact O-N 3.44Å; V98-S100 PolarHBondContact O-N 3.01Å; V98-I101 PolarHBondContact O-N 3.13Å; V98-L102 HydrophobicContact CG1-CD1 3.91Å; V98-L102 HydrophobicContact CG1-CG 4.31Å; V98-L102 VanDerWaalsContact O-CG 3.29Å; V98-L102 WeakPolarHBondContact O-CG 3.47Å; V98-L102 PolarHBondContact O-N 3.44Å
99	A	92.1	Very high	92	Very high	41 Å²	41	67.3 Å²	67.3	34%	0.339	38%	0.375	S	S	.	.	H	α-helix	trans	-61.4	-44.6	177.5	0	0	0	0	0	112	R95 G96 I97 I101 L102 V103	R95-A99 WeakPolarHBondContact O-CB 3.35Å; R95-A99 PolarHBondContact O-N 3.48Å; G96-A99 PolarHBondContact O-N 2.91Å; I97-A99 VanDerWaalsContact C-N 3.33Å; I97-A99 PolarHBondContact O-N 3.48Å; A99-I101 PolarHBondContact O-N 3.4Å; A99-L102 PolarHBondContact O-N 3.36Å; A99-V103 VanDerWaalsContact O-CG2 3.31Å; A99-V103 WeakPolarHBondContact O-CG2 3.46Å; A99-V103 PolarHBondContact O-N 2.93Å
100	S	94.2	Very high	92.2	Very high	83 Å²	83	62.9 Å²	62.9	58%	0.58	35%	0.348	S	S	*	.	H	α-helix	trans	-60.5	-42.9	176.2	-60.6	0	0	0	0	112.3	G96 I97 V98 F104	G96-S100 PolarHBondContact O-N 3.33Å; G96-S100 PolarHBondContact O-OG 3.35Å; G96-S100 VanDerWaalsContact O-OG 3.09Å; I97-S100 PolarHBondContact O-N 3.33Å; V98-S100 PolarHBondContact O-N 3.01Å; S100-F104 WeakPolarHBondContact O-CB 3.32Å; S100-F104 PolarHBondContact O-N 3.25Å
101	I	95.5	Very high	92.5	Very high	62 Å²	62	65.6 Å²	65.6	32%	0.318	35%	0.353	S	S	.	.	H	α-helix	trans	-63.1	-46.8	175.9	-68.6	168.3	0	0	0	110.4	I97 V98 A99 V103 F104 L105 V134	I97-I101 HydrophobicContact CG2-CD1 3.86Å; I97-I101 WeakPolarHBondContact O-CG1 3.13Å; I97-I101 PolarHBondContact O-N 3.2Å; V98-I101 PolarHBondContact O-N 3.13Å; A99-I101 PolarHBondContact O-N 3.4Å; I101-V103 PolarHBondContact O-N 3.43Å; I101-F104 PolarHBondContact O-N 3.03Å; I101-L105 HydrophobicContact CG2-CD1 3.79Å; I101-L105 HydrophobicContact CG2-CG 4.18Å; I101-L105 WeakPolarHBondContact O-CB 3.42Å; I101-L105 VanDerWaalsContact O-CG 3.27Å; I101-L105 WeakPolarHBondContact O-CG 3.36Å; I101-L105 PolarHBondContact O-N 3.4Å; I101-V134 HydrophobicContact CD1-CG1 4.26Å; I101-V134 HydrophobicContact CG1-CG1 4.28Å; I101-V134 HydrophobicContact CG2-CG1 4.09Å; I101-V134 HydrophobicContact CG2-CG2 4.32Å
102	L	93.7	Very high	92.7	Very high	98 Å²	98	61.3 Å²	61.3	51%	0.513	34%	0.34	S	S	.	.	H	α-helix	trans	-61.5	-43.9	179.6	-71	173.6	0	0	0	112	V98 A99 F104 L105 C106	V98-L102 HydrophobicContact CG1-CD1 3.91Å; V98-L102 HydrophobicContact CG1-CG 4.31Å; V98-L102 VanDerWaalsContact O-CG 3.29Å; V98-L102 WeakPolarHBondContact O-CG 3.47Å; V98-L102 PolarHBondContact O-N 3.44Å; A99-L102 PolarHBondContact O-N 3.36Å; L102-F104 PolarHBondContact O-N 2.92Å; L102-L105 PolarHBondContact O-N 3.4Å; L102-C106 WeakPolarHBondContact O-CB 3.24Å; L102-C106 PolarHBondContact O-N 2.98Å; L102-C106 PolarHBondContact O-SG 3.07Å; L102-C106 VanDerWaalsContact O-SG 3.34Å
103	V	93.1	Very high	92.7	Very high	56 Å²	56	68 Å²	68	34%	0.339	37%	0.367	S	S	.	.	H	α-helix	trans	-60.9	-45.4	175.6	172.1	0	0	0	0	110.7	L72 A99 I101 C106 F107	L72-V103 HydrophobicContact CD2-CG2 4.3Å; A99-V103 VanDerWaalsContact O-CG2 3.31Å; A99-V103 WeakPolarHBondContact O-CG2 3.46Å; A99-V103 PolarHBondContact O-N 2.93Å; I101-V103 PolarHBondContact O-N 3.43Å; V103-C106 PolarHBondContact O-N 3.46Å; V103-F107 WeakPolarHBondContact O-CB 3.48Å; V103-F107 PolarHBondContact O-N 2.61Å
104	F	95.6	Very high	92.7	Very high	77 Å²	77	68.4 Å²	68.4	34%	0.338	37%	0.366	S	S	.	.	H	α-helix	trans	-60.5	-44.7	175.7	172.8	-98.8	0	0	0	112.2	S100 I101 L102 F107 G108 C130 V133 V134	S100-F104 WeakPolarHBondContact O-CB 3.32Å; S100-F104 PolarHBondContact O-N 3.25Å; I101-F104 PolarHBondContact O-N 3.03Å; L102-F104 PolarHBondContact O-N 2.92Å; F104-F107 PolarHBondContact O-N 3.04Å; F104-G108 PolarHBondContact O-N 3.28Å; F104-C130 HydrophobicContact CE1-CB 4.08Å; F104-V133 HydrophobicContact CE1-CB 4.34Å; F104-V133 HydrophobicContact CE1-CG1 4.35Å; F104-V133 HydrophobicContact CZ-CB 4.21Å; F104-V133 HydrophobicContact CZ-CG1 3.91Å; F104-V134 HydrophobicContact CD1-CG2 3.57Å; F104-V134 HydrophobicContact CE1-CG2 3.67Å
105	L	95.9	Very high	92.7	Very high	21 Å²	21	64.9 Å²	64.9	11%	0.11	36%	0.361	C	S	.	.	H	α-helix	trans	-63.5	-44	178	-69.5	173.6	0	0	0	111.4	I101 L102 G108 V109 F127 C130 V131 V134	I101-L105 HydrophobicContact CG2-CD1 3.79Å; I101-L105 HydrophobicContact CG2-CG 4.18Å; I101-L105 WeakPolarHBondContact O-CB 3.42Å; I101-L105 VanDerWaalsContact O-CG 3.27Å; I101-L105 WeakPolarHBondContact O-CG 3.36Å; I101-L105 PolarHBondContact O-N 3.4Å; L102-L105 PolarHBondContact O-N 3.4Å; L105-G108 PolarHBondContact O-N 3.2Å; L105-V109 WeakPolarHBondContact O-CB 3.49Å; L105-V109 WeakPolarHBondContact O-CG2 3.45Å; L105-V109 PolarHBondContact O-N 3Å; L105-F127 HydrophobicContact CD1-CE2 4.1Å; L105-F127 HydrophobicContact CD2-CE2 4.46Å; L105-C130 HydrophobicContact CD2-CB 3.71Å; L105-V131 HydrophobicContact CD2-CG2 3.91Å; L105-V134 HydrophobicContact CD2-CG2 4.24Å
106	C	93.9	Very high	92.7	Very high	50 Å²	50	64.1 Å²	64.1	34%	0.338	36%	0.364	S	S	.	.	H	α-helix	trans	-62.5	-43.7	176.1	-71.6	0	0	0	0	112.2	V68 L72 L102 V103 T110	V68-C106 HydrophobicContact CG1-CB 4.2Å; L72-C106 HydrophobicContact CD1-CB 3.94Å; L72-C106 HydrophobicContact CD2-CB 4.21Å; L102-C106 WeakPolarHBondContact O-CB 3.24Å; L102-C106 PolarHBondContact O-N 2.98Å; L102-C106 PolarHBondContact O-SG 3.07Å; L102-C106 VanDerWaalsContact O-SG 3.34Å; V103-C106 PolarHBondContact O-N 3.46Å; C106-T110 WeakPolarHBondContact O-CG2 3.25Å; C106-T110 PolarHBondContact O-N 2.96Å; C106-T110 PolarHBondContact O-OG1 3.5Å
107	F	93.1	Very high	92.6	Very high	121 Å²	121	64.3 Å²	64.3	53%	0.531	36%	0.356	S	S	.	.	H	α-helix	trans	-60.4	-50.6	173.7	172.8	-96.3	0	0	0	111	V103 F104 V109 T110 Q111	V103-F107 WeakPolarHBondContact O-CB 3.48Å; V103-F107 PolarHBondContact O-N 2.61Å; F104-F107 PolarHBondContact O-N 3.04Å; F107-V109 PolarHBondContact O-N 3.09Å; F107-T110 PolarHBondContact O-N 3.42Å; F107-T110 PolarHBondContact O-OG1 2.88Å; F107-Q111 HydrophobicContact CD2-CG 3.83Å; F107-Q111 HydrophobicContact CE1-CB 4.4Å; F107-Q111 HydrophobicContact CE1-CG 4.42Å; F107-Q111 HydrophobicContact CE2-CB 4.39Å; F107-Q111 HydrophobicContact CE2-CG 3.59Å; F107-Q111 HydrophobicContact CG-CG 4.36Å; F107-Q111 HydrophobicContact CZ-CB 4.21Å; F107-Q111 HydrophobicContact CZ-CG 3.9Å; F107-Q111 WeakPolarHBondContact O-CB 3.4Å; F107-Q111 WeakPolarHBondContact O-CG 3.3Å; F107-Q111 PolarHBondContact O-N 3.2Å
108	G	93.3	Very high	92.3	Very high	6 Å²	6	62.3 Å²	62.3	6%	0.062	35%	0.349	C	S	.	.	H	α-helix	trans	-61.6	-44.5	-178.1	0	0	0	0	0	113.2	F104 L105 T110 Q111 A112 C130	F104-G108 PolarHBondContact O-N 3.28Å; L105-G108 PolarHBondContact O-N 3.2Å; G108-T110 PolarHBondContact O-N 2.88Å; G108-Q111 PolarHBondContact O-N 2.89Å; G108-A112 WeakPolarHBondContact O-CA 3.4Å; G108-A112 WeakPolarHBondContact O-CB 3.38Å; G108-A112 PolarHBondContact O-N 3.3Å; G108-C130 VanDerWaalsContact C-SG 3.51Å; G108-C130 WeakPolarHBondContact CA-SG 3.41Å
109	V	94.3	Very high	92.2	Very high	30 Å²	30	59.7 Å²	59.7	18%	0.182	33%	0.331	C	S	.	.	H	α-helix	trans	-59.7	-36	176.5	169.6	0	0	0	0	112.2	L105 F107 A123 R126 F127	L105-V109 WeakPolarHBondContact O-CB 3.49Å; L105-V109 WeakPolarHBondContact O-CG2 3.45Å; L105-V109 PolarHBondContact O-N 3Å; F107-V109 PolarHBondContact O-N 3.09Å; V109-A123 HydrophobicContact CG1-CB 3.7Å; V109-R126 WeakPolarHBondContact O-CD 3.42Å; V109-R126 PolarHBondContact O-NH1 2.72Å; V109-F127 HydrophobicContact CG2-CB 3.65Å; V109-F127 HydrophobicContact CG2-CD2 4.15Å; V109-F127 HydrophobicContact CG2-CG 4.42Å
110	T	92.4	Very high	92.1	Very high	21 Å²	21	59.2 Å²	59.2	13%	0.129	33%	0.325	C	S	.	.	H	α-helix	trans	-84.4	-30.8	-177.3	55.6	0	0	0	0	113.5	V68 C106 F107 G108	V68-T110 HydrophobicContact CB-CG2 4.14Å; V68-T110 HydrophobicContact CG1-CG2 4.09Å; V68-T110 HydrophobicContact CG2-CG2 3.86Å; C106-T110 WeakPolarHBondContact O-CG2 3.25Å; C106-T110 PolarHBondContact O-N 2.96Å; C106-T110 PolarHBondContact O-OG1 3.5Å; F107-T110 PolarHBondContact O-N 3.42Å; F107-T110 PolarHBondContact O-OG1 2.88Å; G108-T110 PolarHBondContact O-N 2.88Å
111	Q	92.6	Very high	91.9	Very high	106 Å²	106	57 Å²	57	50%	0.495	31%	0.305	S	S	.	.	H	α-helix	trans	-105.7	-23.5	-172.6	-59	-60.4	-26.2	0	0	114.7	F107 G108	F107-Q111 HydrophobicContact CD2-CG 3.83Å; F107-Q111 HydrophobicContact CE1-CB 4.4Å; F107-Q111 HydrophobicContact CE1-CG 4.42Å; F107-Q111 HydrophobicContact CE2-CB 4.39Å; F107-Q111 HydrophobicContact CE2-CG 3.59Å; F107-Q111 HydrophobicContact CG-CG 4.36Å; F107-Q111 HydrophobicContact CZ-CB 4.21Å; F107-Q111 HydrophobicContact CZ-CG 3.9Å; F107-Q111 WeakPolarHBondContact O-CB 3.4Å; F107-Q111 WeakPolarHBondContact O-CG 3.3Å; F107-Q111 PolarHBondContact O-N 3.2Å; G108-Q111 PolarHBondContact O-N 2.89Å
112	A	92.2	Very high	91.7	Very high	22 Å²	22	54.8 Å²	54.8	18%	0.182	30%	0.295	C	S	.	.	S	Bend	trans	-62.7	147.1	179	0	0	0	0	0	111	G108 R126 L129	G108-A112 WeakPolarHBondContact O-CA 3.4Å; G108-A112 WeakPolarHBondContact O-CB 3.38Å; G108-A112 PolarHBondContact O-N 3.3Å; A112-R126 HydrophobicContact CB-CB 4.16Å; A112-R126 HydrophobicContact CB-CG 4.06Å; A112-R126 VanDerWaalsContact O-CD 3.31Å; A112-R126 WeakPolarHBondContact O-CD 3.39Å; A112-R126 PolarHBondContact O-NE 3.05Å; A112-R126 VanDerWaalsContact O-NE 3.11Å; A112-R126 PolarHBondContact O-NH1 2.89Å; A112-L129 HydrophobicContact CB-CD2 4.46Å
113	K	91.1	Very high	91.6	Very high	188 Å²	188	51.5 Å²	51.5	82%	0.817	28%	0.282	S	S	*	.	P	Polyproline II helix	trans	-72.6	151.9	174.9	-64.2	-176.9	-179.3	-179.7	0	110.1
114	D	89.8	Confident	91.7	Very high	85 Å²	85	52.9 Å²	52.9	46%	0.455	28%	0.282	S	S	.	.	P	Polyproline II helix	trans	-66.6	134.1	173.5	-68.8	-35.8	0	0	0	111.3	P122 R126	D114-P122 WeakPolarHBondContact OD1-CB 3.29Å; D114-R126 IonicContact OD1-CZ 3.69Å; D114-R126 IonicContact OD1-NE 3.68Å; D114-R126 PolarHBondContact OD1-NE 3.1Å; D114-R126 IonicContact OD1-NH2 2.78Å; D114-R126 PolarHBondContact OD1-NH2 3.26Å; D114-R126 IonicContact OD2-NH2 3.6Å; D114-R126 PolarHBondContact OD2-NH2 3.47Å
115	G	88.6	Confident	91.7	Very high	34 Å²	34	51 Å²	51	35%	0.351	27%	0.273	S	S	.	.			trans	-83.4	-168.2	171	0	0	0	0	0	112.1	F117	G115-F117 PolarHBondContact O-N 3.31Å
116	P	89.9	Confident	91.7	Very high	48 Å²	48	51.8 Å²	51.8	31%	0.312	27%	0.274	S	S	.	.	S	Bend	trans	-69.7	-14.3	-178.8	29.8	-37.3	0	0	0	113.9	V360 R363 E364	P116-V360 HydrophobicContact CG-CG1 3.97Å; P116-R363 HydrophobicContact CB-CB 4.49Å; P116-R363 HydrophobicContact CB-CG 3.62Å; P116-R363 HydrophobicContact CG-CB 4.2Å; P116-R363 HydrophobicContact CG-CG 3.87Å; P116-E364 HydrophobicContact CG-CG 3.93Å
117	F	90.6	Very high	91.8	Very high	38 Å²	38	53.1 Å²	53.1	17%	0.167	27%	0.274	C	S	.	.			trans	-105	131.5	178.6	-65.8	-5.8	0	0	0	111.1	G115 W125 G359 V360 R363	G115-F117 PolarHBondContact O-N 3.31Å; F117-W125 HydrophobicContact CB-CD2 3.76Å; F117-W125 HydrophobicContact CB-CG 3.84Å; F117-W125 HydrophobicContact CB-CZ2 4.1Å; F117-W125 HydrophobicContact CD2-CD2 4.03Å; F117-W125 AromaticContact CD2-CE2 3.86Å; F117-W125 HydrophobicContact CD2-CE3 4.01Å; F117-W125 AromaticContact CD2-CH2 3.69Å; F117-W125 HydrophobicContact CD2-CH2 3.69Å; F117-W125 AromaticContact CD2-CZ2 3.7Å; F117-W125 HydrophobicContact CD2-CZ2 3.7Å; F117-W125 AromaticContact CD2-CZ3 3.84Å; F117-W125 HydrophobicContact CD2-CZ3 3.84Å; F117-W125 HydrophobicContact CE2-CH2 4.28Å; F117-W125 HydrophobicContact CE2-CZ3 4.43Å; F117-W125 HydrophobicContact CG-CD2 4.44Å; F117-W125 HydrophobicContact CG-CZ2 4.35Å; F117-G359 VanDerWaalsContact CZ-O 3.27Å; F117-G359 WeakPolarHBondContact CZ-O 3.37Å; F117-V360 HydrophobicContact CD2-CB 4.43Å; F117-V360 HydrophobicContact CD2-CG2 3.41Å; F117-V360 VanDerWaalsContact CD2-CG2 3.41Å; F117-V360 HydrophobicContact CE2-CB 4.37Å; F117-V360 HydrophobicContact CE2-CG2 3.66Å; F117-V360 HydrophobicContact CG-CG2 4.13Å; F117-R363 HydrophobicContact CE1-CB 3.82Å; F117-R363 HydrophobicContact CE1-CG 3.91Å; F117-R363 HydrophobicContact CZ-CB 4.17Å
118	S	85.9	Confident	92	Very high	47 Å²	47	49 Å²	49	33%	0.329	26%	0.255	S	S	.	.			trans	-112.8	-16.6	-179.3	-43.6	0	0	0	0	113.8	H121 P122	S118-H121 CarbonylContact O-C 3.45Å; S118-H121 VanDerWaalsContact O-C 3.31Å; S118-H121 WeakPolarHBondContact O-CA 3.42Å; S118-P122 VanDerWaalsContact O-CD 3.31Å; S118-P122 WeakPolarHBondContact O-CD 3.46Å
119	R	88.5	Confident	92.2	Very high	20 Å²	20	50.3 Å²	50.3	8%	0.075	26%	0.26	C	S	.	.	S	Bend	trans	-117.6	141.1	-177.1	-65	-78.9	-178.6	-170	-15.4	109.9	W125 Q294 T296	R119-W125 VanDerWaalsContact C-NE1 3.33Å; R119-W125 WeakPolarHBondContact O-CZ2 3.48Å; R119-W125 PolarHBondContact O-NE1 3Å; R119-Q294 VanDerWaalsContact NH1-CD 3.27Å; R119-T296 WeakPolarHBondContact CB-O 3.43Å
120	P	89.3	Confident	92.4	Very high	31 Å²	31	49.2 Å²	49.2	20%	0.201	25%	0.254	C	S	.	.	S	Bend	cis	-76.2	-23	13.2	29.9	-35.6	0	0	0	114.1	Y124 Q294 F295	P120-Y124 HydrophobicContact CG-CD1 4.27Å; P120-Y124 HydrophobicContact CG-CG 4.16Å; P120-Q294 WeakPolarHBondContact CA-O 3.36Å; P120-Q294 HydrophobicContact CB-CG 4.49Å; P120-Q294 PolarHBondContact O-NE2 2.88Å; P120-F295 HydrophobicContact CB-CD1 4.02Å; P120-F295 HydrophobicContact CB-CE1 4.22Å
121	H	90.2	Very high	92.6	Very high	36 Å²	36	49.6 Å²	49.6	17%	0.167	26%	0.256	C	S	.	.			trans	-158.7	148.9	169.5	-168.4	-97.2	0	0	0	109.3	F60 W61 S118 A123 Y124	F60-H121 AromaticContact CE1-CD2 3.48Å; F60-H121 VanDerWaalsContact CE1-CD2 3.48Å; F60-H121 WeakPolarHBondContact CE1-CD2 3.5Å; F60-H121 AromaticContact CZ-CD2 3.96Å; F60-H121 PolarHBondContact O-NE2 3.42Å; W61-H121 AromaticContact CE3-CD2 3.68Å; W61-H121 AromaticContact CE3-NE2 3.85Å; W61-H121 AromaticContact CZ3-CD2 3.76Å; S118-H121 CarbonylContact O-C 3.45Å; S118-H121 VanDerWaalsContact O-C 3.31Å; S118-H121 WeakPolarHBondContact O-CA 3.42Å; H121-A123 VanDerWaalsContact C-N 3.26Å; H121-A123 WeakPolarHBondContact ND1-CB 3.3Å; H121-A123 PolarHBondContact ND1-N 3.24Å; H121-A123 VanDerWaalsContact ND1-N 3.12Å; H121-A123 PolarHBondContact O-N 2.96Å; H121-Y124 VanDerWaalsContact O-CB 3.24Å; H121-Y124 WeakPolarHBondContact O-CB 3.45Å; H121-Y124 PolarHBondContact O-N 3.27Å
122	P	91.5	Very high	92.9	Very high	15 Å²	15	44.6 Å²	44.6	10%	0.097	23%	0.233	C	C	.	.	H	α-helix	trans	-63.2	-34.2	179.9	-19.9	31.4	0	0	0	112.5	W61 D114 S118 Y124 W125 R126	W61-P122 HydrophobicContact CE3-CG 4.44Å; W61-P122 HydrophobicContact CZ3-CG 4.49Å; D114-P122 WeakPolarHBondContact OD1-CB 3.29Å; S118-P122 VanDerWaalsContact O-CD 3.31Å; S118-P122 WeakPolarHBondContact O-CD 3.46Å; P122-Y124 PolarHBondContact O-N 2.89Å; P122-W125 PolarHBondContact O-N 3.45Å; P122-W125 VanDerWaalsContact O-N 3.09Å; P122-R126 WeakPolarHBondContact O-CG 3.42Å; P122-R126 PolarHBondContact O-N 3.02Å
123	A	92.9	Very high	93.2	Very high	30 Å²	30	45.8 Å²	45.8	25%	0.248	24%	0.238	C	C	.	.	H	α-helix	trans	-56.2	-33	173.5	0	0	0	0	0	113.3	V109 H121 F127	V109-A123 HydrophobicContact CG1-CB 3.7Å; H121-A123 VanDerWaalsContact C-N 3.26Å; H121-A123 WeakPolarHBondContact ND1-CB 3.3Å; H121-A123 PolarHBondContact ND1-N 3.24Å; H121-A123 VanDerWaalsContact ND1-N 3.12Å; H121-A123 PolarHBondContact O-N 2.96Å; A123-F127 VanDerWaalsContact O-CB 3.24Å; A123-F127 WeakPolarHBondContact O-CB 3.32Å; A123-F127 PolarHBondContact O-N 2.97Å
124	Y	94.4	Very high	93.5	Very high	84 Å²	84	38.3 Å²	38.3	33%	0.329	21%	0.208	S	C	.	.	H	α-helix	trans	-64.2	-43.1	177.4	-179.4	-94.9	0	0	0	111.5	P120 H121 P122 F127 W128 N356	P120-Y124 HydrophobicContact CG-CD1 4.27Å; P120-Y124 HydrophobicContact CG-CG 4.16Å; H121-Y124 VanDerWaalsContact O-CB 3.24Å; H121-Y124 WeakPolarHBondContact O-CB 3.45Å; H121-Y124 PolarHBondContact O-N 3.27Å; P122-Y124 PolarHBondContact O-N 2.89Å; Y124-F127 WeakPolarHBondContact O-CB 3.32Å; Y124-F127 PolarHBondContact O-N 3.15Å; Y124-W128 AromaticContact CD1-CD1 3.84Å; Y124-W128 AromaticContact CE1-CD1 3.47Å; Y124-W128 VanDerWaalsContact CE1-CD1 3.47Å; Y124-W128 AromaticContact CE1-NE1 3.39Å; Y124-W128 AromaticContact CE2-NE1 3.55Å; Y124-W128 AromaticContact CZ-CD1 3.66Å; Y124-W128 AromaticContact CZ-NE1 3.06Å; Y124-W128 PolarHBondContact O-N 2.65Å; Y124-W128 VanDerWaalsContact O-N 3.17Å; Y124-W128 PolarHBondContact OH-NE1 3.2Å; Y124-W128 VanDerWaalsContact OH-NE1 3.07Å; Y124-N356 PolarHBondContact OH-OD1 3.29Å
125	W	95.2	Very high	93.9	Very high	39 Å²	39	36.4 Å²	36.4	15%	0.148	20%	0.195	C	C	.	.	H	α-helix	trans	-76.4	-37	-179.3	-57.1	112.9	0	0	0	112.4	F117 R119 P122 F127 W128 L129 V360	F117-W125 HydrophobicContact CB-CD2 3.76Å; F117-W125 HydrophobicContact CB-CG 3.84Å; F117-W125 HydrophobicContact CB-CZ2 4.1Å; F117-W125 HydrophobicContact CD2-CD2 4.03Å; F117-W125 AromaticContact CD2-CE2 3.86Å; F117-W125 HydrophobicContact CD2-CE3 4.01Å; F117-W125 AromaticContact CD2-CH2 3.69Å; F117-W125 HydrophobicContact CD2-CH2 3.69Å; F117-W125 AromaticContact CD2-CZ2 3.7Å; F117-W125 HydrophobicContact CD2-CZ2 3.7Å; F117-W125 AromaticContact CD2-CZ3 3.84Å; F117-W125 HydrophobicContact CD2-CZ3 3.84Å; F117-W125 HydrophobicContact CE2-CH2 4.28Å; F117-W125 HydrophobicContact CE2-CZ3 4.43Å; F117-W125 HydrophobicContact CG-CD2 4.44Å; F117-W125 HydrophobicContact CG-CZ2 4.35Å; R119-W125 VanDerWaalsContact C-NE1 3.33Å; R119-W125 WeakPolarHBondContact O-CZ2 3.48Å; R119-W125 PolarHBondContact O-NE1 3Å; P122-W125 PolarHBondContact O-N 3.45Å; P122-W125 VanDerWaalsContact O-N 3.09Å; W125-F127 VanDerWaalsContact C-N 3.28Å; W125-F127 PolarHBondContact O-N 2.88Å; W125-W128 PolarHBondContact O-N 2.9Å; W125-L129 PolarHBondContact O-N 2.86Å; W125-V360 HydrophobicContact CD2-CG2 4.33Å; W125-V360 HydrophobicContact CE3-CG2 3.59Å; W125-V360 HydrophobicContact CZ3-CG2 3.91Å
126	R	95.9	Very high	94.4	Very high	36 Å²	36	35.8 Å²	35.8	14%	0.136	18%	0.182	C	C	.	.	H	α-helix	trans	-60.9	-39.8	170.2	-64.5	175.5	-167.5	-173.4	-2.4	111.3	V109 A112 D114 P122 L129 C130	V109-R126 WeakPolarHBondContact O-CD 3.42Å; V109-R126 PolarHBondContact O-NH1 2.72Å; A112-R126 HydrophobicContact CB-CB 4.16Å; A112-R126 HydrophobicContact CB-CG 4.06Å; A112-R126 VanDerWaalsContact O-CD 3.31Å; A112-R126 WeakPolarHBondContact O-CD 3.39Å; A112-R126 PolarHBondContact O-NE 3.05Å; A112-R126 VanDerWaalsContact O-NE 3.11Å; A112-R126 PolarHBondContact O-NH1 2.89Å; D114-R126 IonicContact OD1-CZ 3.69Å; D114-R126 IonicContact OD1-NE 3.68Å; D114-R126 PolarHBondContact OD1-NE 3.1Å; D114-R126 IonicContact OD1-NH2 2.78Å; D114-R126 PolarHBondContact OD1-NH2 3.26Å; D114-R126 IonicContact OD2-NH2 3.6Å; D114-R126 PolarHBondContact OD2-NH2 3.47Å; P122-R126 WeakPolarHBondContact O-CG 3.42Å; P122-R126 PolarHBondContact O-N 3.02Å; R126-L129 PolarHBondContact O-N 2.77Å; R126-C130 PolarHBondContact O-N 2.71Å; R126-C130 PolarHBondContact O-SG 3.41Å
127	F	96.6	Very high	94.8	Very high	78 Å²	78	38.6 Å²	38.6	34%	0.342	19%	0.194	S	C	.	.	H	α-helix	trans	-57.7	-51.3	174.8	171.3	-98.7	0	0	0	111.1	L105 V109 A123 Y124 W125 L129 C130 V131	L105-F127 HydrophobicContact CD1-CE2 4.1Å; L105-F127 HydrophobicContact CD2-CE2 4.46Å; V109-F127 HydrophobicContact CG2-CB 3.65Å; V109-F127 HydrophobicContact CG2-CD2 4.15Å; V109-F127 HydrophobicContact CG2-CG 4.42Å; A123-F127 VanDerWaalsContact O-CB 3.24Å; A123-F127 WeakPolarHBondContact O-CB 3.32Å; A123-F127 PolarHBondContact O-N 2.97Å; Y124-F127 WeakPolarHBondContact O-CB 3.32Å; Y124-F127 PolarHBondContact O-N 3.15Å; W125-F127 VanDerWaalsContact C-N 3.28Å; W125-F127 PolarHBondContact O-N 2.88Å; F127-L129 VanDerWaalsContact C-N 3.33Å; F127-L129 PolarHBondContact O-N 3.06Å; F127-C130 PolarHBondContact O-N 2.88Å; F127-C130 VanDerWaalsContact O-N 3.12Å; F127-V131 HydrophobicContact CD1-CG2 4.07Å; F127-V131 HydrophobicContact CD2-CG2 4.3Å; F127-V131 HydrophobicContact CE1-CG2 3.64Å; F127-V131 HydrophobicContact CE2-CG2 3.9Å; F127-V131 HydrophobicContact CG-CG2 4.38Å; F127-V131 HydrophobicContact CZ-CG2 3.55Å; F127-V131 WeakPolarHBondContact O-CG2 3.16Å; F127-V131 PolarHBondContact O-N 3.12Å
128	W	97.4	Very high	95	Very high	36 Å²	36	40.1 Å²	40.1	14%	0.136	20%	0.201	C	C	.	.	H	α-helix	trans	-63.1	-37	178.9	-78.6	111	0	0	0	113.4	Y124 W125 C130 V131 S132 V352 F353 N356 V357	Y124-W128 AromaticContact CD1-CD1 3.84Å; Y124-W128 AromaticContact CE1-CD1 3.47Å; Y124-W128 VanDerWaalsContact CE1-CD1 3.47Å; Y124-W128 AromaticContact CE1-NE1 3.39Å; Y124-W128 AromaticContact CE2-NE1 3.55Å; Y124-W128 AromaticContact CZ-CD1 3.66Å; Y124-W128 AromaticContact CZ-NE1 3.06Å; Y124-W128 PolarHBondContact O-N 2.65Å; Y124-W128 VanDerWaalsContact O-N 3.17Å; Y124-W128 PolarHBondContact OH-NE1 3.2Å; Y124-W128 VanDerWaalsContact OH-NE1 3.07Å; W125-W128 PolarHBondContact O-N 2.9Å; W128-C130 VanDerWaalsContact C-N 3.33Å; W128-C130 PolarHBondContact O-N 3.35Å; W128-V131 HydrophobicContact CE3-CB 4.26Å; W128-V131 HydrophobicContact CE3-CG1 4.12Å; W128-V131 HydrophobicContact CZ3-CG1 4.17Å; W128-V131 PolarHBondContact O-N 2.96Å; W128-S132 PolarHBondContact O-N 3.18Å; W128-S132 PolarHBondContact O-OG 3.29Å; W128-V352 HydrophobicContact CH2-CG1 4.17Å; W128-V352 HydrophobicContact CZ2-CG1 4.45Å; W128-F353 AromaticContact CE3-CD2 3.91Å; W128-F353 HydrophobicContact CE3-CD2 3.91Å; W128-F353 HydrophobicContact CZ3-CB 4.05Å; W128-F353 AromaticContact CZ3-CD2 3.77Å; W128-F353 HydrophobicContact CZ3-CD2 3.77Å; W128-F353 HydrophobicContact CZ3-CG 4.37Å; W128-N356 HydrophobicContact CD2-CB 3.75Å; W128-N356 HydrophobicContact CE3-CB 4.25Å; W128-N356 HydrophobicContact CG-CB 4.04Å; W128-N356 HydrophobicContact CZ2-CB 4.05Å; W128-N356 WeakPolarHBondContact CZ2-ND2 3.33Å; W128-V357 HydrophobicContact CB-CG1 4.21Å; W128-V357 HydrophobicContact CE3-CG1 4.33Å
129	L	97.2	Very high	95.6	Very high	32 Å²	32	38.3 Å²	38.3	17%	0.168	19%	0.187	C	C	.	.	H	α-helix	trans	-58.2	-46	171.8	176.8	66.5	0	0	0	111.6	A112 W125 R126 F127 S132 V133 P380 L384	A112-L129 HydrophobicContact CB-CD2 4.46Å; W125-L129 PolarHBondContact O-N 2.86Å; R126-L129 PolarHBondContact O-N 2.77Å; F127-L129 VanDerWaalsContact C-N 3.33Å; F127-L129 PolarHBondContact O-N 3.06Å; L129-S132 WeakPolarHBondContact O-CB 3.24Å; L129-S132 PolarHBondContact O-N 3.06Å; L129-V133 PolarHBondContact O-N 3.5Å; L129-P380 HydrophobicContact CD1-CB 4.19Å; L129-L384 HydrophobicContact CD1-CD1 3.56Å
130	C	97.8	Very high	96	Very high	7 Å²	7	40.4 Å²	40.4	5%	0.047	20%	0.2	C	C	.	.	H	α-helix	trans	-68.2	-37.9	177.6	-60.9	0	0	0	0	112.3	F104 L105 G108 R126 F127 W128 S132 V133 V134	F104-C130 HydrophobicContact CE1-CB 4.08Å; L105-C130 HydrophobicContact CD2-CB 3.71Å; G108-C130 VanDerWaalsContact C-SG 3.51Å; G108-C130 WeakPolarHBondContact CA-SG 3.41Å; R126-C130 PolarHBondContact O-N 2.71Å; R126-C130 PolarHBondContact O-SG 3.41Å; F127-C130 PolarHBondContact O-N 2.88Å; F127-C130 VanDerWaalsContact O-N 3.12Å; W128-C130 VanDerWaalsContact C-N 3.33Å; W128-C130 PolarHBondContact O-N 3.35Å; C130-S132 VanDerWaalsContact C-N 3.27Å; C130-S132 PolarHBondContact O-N 3.26Å; C130-V133 PolarHBondContact O-N 2.97Å; C130-V134 WeakPolarHBondContact O-CG2 3.14Å; C130-V134 PolarHBondContact O-N 2.89Å
131	V	98	Very high	96.4	Very high	30 Å²	30	42.8 Å²	42.8	18%	0.182	21%	0.207	C	C	.	.	H	α-helix	trans	-59.9	-39	172	171.5	0	0	0	0	110.8	L105 F127 W128 V133 V134 Y135 F353	L105-V131 HydrophobicContact CD2-CG2 3.91Å; F127-V131 HydrophobicContact CD1-CG2 4.07Å; F127-V131 HydrophobicContact CD2-CG2 4.3Å; F127-V131 HydrophobicContact CE1-CG2 3.64Å; F127-V131 HydrophobicContact CE2-CG2 3.9Å; F127-V131 HydrophobicContact CG-CG2 4.38Å; F127-V131 HydrophobicContact CZ-CG2 3.55Å; F127-V131 WeakPolarHBondContact O-CG2 3.16Å; F127-V131 PolarHBondContact O-N 3.12Å; W128-V131 HydrophobicContact CE3-CB 4.26Å; W128-V131 HydrophobicContact CE3-CG1 4.12Å; W128-V131 HydrophobicContact CZ3-CG1 4.17Å; W128-V131 PolarHBondContact O-N 2.96Å; V131-V133 VanDerWaalsContact C-N 3.34Å; V131-V133 PolarHBondContact O-N 2.92Å; V131-V134 PolarHBondContact O-N 3.29Å; V131-Y135 WeakPolarHBondContact O-CB 3.35Å; V131-Y135 PolarHBondContact O-N 2.94Å; V131-F353 HydrophobicContact CG1-CD2 3.93Å; V131-F353 HydrophobicContact CG1-CE2 4.01Å
132	S	98.3	Very high	96.7	Very high	0 Å²	0	41.3 Å²	41.3	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-62.8	-39.5	175	-55.6	0	0	0	0	112.7	W128 L129 C130 Y135 E136 F353 V357 Q381	W128-S132 PolarHBondContact O-N 3.18Å; W128-S132 PolarHBondContact O-OG 3.29Å; L129-S132 WeakPolarHBondContact O-CB 3.24Å; L129-S132 PolarHBondContact O-N 3.06Å; C130-S132 VanDerWaalsContact C-N 3.27Å; C130-S132 PolarHBondContact O-N 3.26Å; S132-Y135 PolarHBondContact O-N 2.74Å; S132-E136 WeakPolarHBondContact O-CB 3.35Å; S132-E136 PolarHBondContact O-N 3.12Å; S132-F353 VanDerWaalsContact OG-CE2 3.31Å; S132-F353 WeakPolarHBondContact OG-CE2 3.43Å; S132-F353 WeakPolarHBondContact OG-CZ 3.23Å; S132-V357 WeakPolarHBondContact OG-CG1 3.43Å; S132-Q381 PolarHBondContact OG-NE2 3.11Å
133	V	98.1	Very high	96.9	Very high	47 Å²	47	42.3 Å²	42.3	29%	0.285	21%	0.205	S	C	.	.	H	α-helix	trans	-64	-46	174.3	177.6	0	0	0	0	110.8	F104 L129 C130 V131 Y135 E136 L137 L384	F104-V133 HydrophobicContact CE1-CB 4.34Å; F104-V133 HydrophobicContact CE1-CG1 4.35Å; F104-V133 HydrophobicContact CZ-CB 4.21Å; F104-V133 HydrophobicContact CZ-CG1 3.91Å; L129-V133 PolarHBondContact O-N 3.5Å; C130-V133 PolarHBondContact O-N 2.97Å; V131-V133 VanDerWaalsContact C-N 3.34Å; V131-V133 PolarHBondContact O-N 2.92Å; V133-Y135 VanDerWaalsContact C-N 3.31Å; V133-Y135 PolarHBondContact O-N 3.42Å; V133-E136 PolarHBondContact O-N 2.97Å; V133-L137 HydrophobicContact CG1-CD1 4.12Å; V133-L137 HydrophobicContact CG1-CG 4.44Å; V133-L137 VanDerWaalsContact O-CG 3.29Å; V133-L137 WeakPolarHBondContact O-CG 3.41Å; V133-L137 PolarHBondContact O-N 3.14Å; V133-L384 HydrophobicContact CG2-CD1 3.72Å; V133-L384 HydrophobicContact CG2-CD2 4.21Å
134	V	97.9	Very high	97.1	Very high	31 Å²	31	48.6 Å²	48.6	19%	0.188	23%	0.227	C	C	.	.	H	α-helix	trans	-61.2	-42.5	177.2	174.7	0	0	0	0	111	I101 F104 L105 C130 V131 L137 F138	I101-V134 HydrophobicContact CD1-CG1 4.26Å; I101-V134 HydrophobicContact CG1-CG1 4.28Å; I101-V134 HydrophobicContact CG2-CG1 4.09Å; I101-V134 HydrophobicContact CG2-CG2 4.32Å; F104-V134 HydrophobicContact CD1-CG2 3.57Å; F104-V134 HydrophobicContact CE1-CG2 3.67Å; L105-V134 HydrophobicContact CD2-CG2 4.24Å; C130-V134 WeakPolarHBondContact O-CG2 3.14Å; C130-V134 PolarHBondContact O-N 2.89Å; V131-V134 PolarHBondContact O-N 3.29Å; V134-L137 PolarHBondContact O-N 2.93Å; V134-F138 WeakPolarHBondContact O-CB 3.36Å; V134-F138 PolarHBondContact O-N 3.46Å
135	Y	97.9	Very high	97.2	Very high	46 Å²	46	46.8 Å²	46.8	18%	0.18	22%	0.221	C	C	.	.	H	α-helix	trans	-63.5	-44.8	178	-175.4	-131.4	0	0	0	111.4	V131 S132 V133 L137 F138 L139 F353 I388 E392	V131-Y135 WeakPolarHBondContact O-CB 3.35Å; V131-Y135 PolarHBondContact O-N 2.94Å; S132-Y135 PolarHBondContact O-N 2.74Å; V133-Y135 VanDerWaalsContact C-N 3.31Å; V133-Y135 PolarHBondContact O-N 3.42Å; Y135-L137 PolarHBondContact O-N 3.29Å; Y135-F138 WeakPolarHBondContact O-CB 3.3Å; Y135-F138 PolarHBondContact O-N 2.82Å; Y135-L139 HydrophobicContact CD1-CD1 4.02Å; Y135-L139 HydrophobicContact CD2-CD1 4.48Å; Y135-L139 HydrophobicContact CD2-CG 4.25Å; Y135-L139 HydrophobicContact CE1-CD1 3.67Å; Y135-L139 HydrophobicContact CE1-CG 4.35Å; Y135-L139 HydrophobicContact CE2-CD1 4.17Å; Y135-L139 HydrophobicContact CE2-CD2 3.95Å; Y135-L139 HydrophobicContact CE2-CG 3.94Å; Y135-L139 HydrophobicContact CG-CD1 4.41Å; Y135-L139 WeakPolarHBondContact O-CG 3.31Å; Y135-L139 PolarHBondContact O-N 3.32Å; Y135-F353 HydrophobicContact CD1-CD1 4.32Å; Y135-F353 AromaticContact CD1-CE1 3.77Å; Y135-F353 HydrophobicContact CD1-CE1 3.77Å; Y135-F353 HydrophobicContact CD1-CE2 4.46Å; Y135-F353 AromaticContact CD1-CZ 3.86Å; Y135-F353 HydrophobicContact CD1-CZ 3.86Å; Y135-F353 HydrophobicContact CE1-CD1 4.45Å; Y135-F353 HydrophobicContact CE1-CE1 4.13Å; Y135-I388 HydrophobicContact CD1-CD1 4.02Å; Y135-I388 HydrophobicContact CD1-CG1 4.21Å; Y135-I388 HydrophobicContact CD1-CG2 3.8Å; Y135-I388 HydrophobicContact CE1-CG2 3.5Å; Y135-E392 WeakPolarHBondContact CE1-OE1 3.35Å; Y135-E392 PolarHBondContact OH-OE1 3.43Å
136	E	98.3	Very high	97.3	Very high	20 Å²	20	48.2 Å²	48.2	9%	0.093	23%	0.234	C	C	.	.	H	α-helix	trans	-61.3	-45.1	176	-179.6	58.3	-167.2	0	0	112.1	S132 V133 F138 L139 I140 I388 T391	S132-E136 WeakPolarHBondContact O-CB 3.35Å; S132-E136 PolarHBondContact O-N 3.12Å; V133-E136 PolarHBondContact O-N 2.97Å; E136-F138 VanDerWaalsContact C-N 3.27Å; E136-F138 PolarHBondContact O-N 3.46Å; E136-L139 PolarHBondContact O-N 3.34Å; E136-I140 HydrophobicContact CG-CD1 4.03Å; E136-I140 VanDerWaalsContact O-CG1 3.3Å; E136-I140 WeakPolarHBondContact O-CG1 3.09Å; E136-I140 PolarHBondContact O-N 2.89Å; E136-I388 HydrophobicContact CB-CG1 4Å; E136-I388 WeakPolarHBondContact OE2-CA 3.42Å; E136-I388 WeakPolarHBondContact OE2-CG1 3.47Å; E136-I388 PolarHBondContact OE2-N 3.18Å; E136-T391 PolarHBondContact OE1-OG1 3.16Å
137	L	97.9	Very high	97.2	Very high	107 Å²	107	47.9 Å²	47.9	56%	0.56	24%	0.236	S	C	*	.	H	α-helix	trans	-60.8	-38.7	175.9	-68.9	173.9	0	0	0	111.9	V133 V134 Y135 F141	V133-L137 HydrophobicContact CG1-CD1 4.12Å; V133-L137 HydrophobicContact CG1-CG 4.44Å; V133-L137 VanDerWaalsContact O-CG 3.29Å; V133-L137 WeakPolarHBondContact O-CG 3.41Å; V133-L137 PolarHBondContact O-N 3.14Å; V134-L137 PolarHBondContact O-N 2.93Å; Y135-L137 PolarHBondContact O-N 3.29Å; L137-F141 PolarHBondContact O-N 3.03Å
138	F	95.9	Very high	97.1	Very high	71 Å²	71	50 Å²	50	31%	0.311	25%	0.247	S	C	.	.	H	α-helix	trans	-65.7	-44.3	175.3	178.1	-106.2	0	0	0	112.1	V134 Y135 E136 I140 F141 I142 F153	V134-F138 WeakPolarHBondContact O-CB 3.36Å; V134-F138 PolarHBondContact O-N 3.46Å; Y135-F138 WeakPolarHBondContact O-CB 3.3Å; Y135-F138 PolarHBondContact O-N 2.82Å; E136-F138 VanDerWaalsContact C-N 3.27Å; E136-F138 PolarHBondContact O-N 3.46Å; F138-I140 VanDerWaalsContact C-N 3.35Å; F138-I140 PolarHBondContact O-N 3.38Å; F138-F141 HydrophobicContact CE2-CD1 4.49Å; F138-F141 WeakPolarHBondContact O-CB 3.32Å; F138-F141 PolarHBondContact O-N 3.12Å; F138-I142 HydrophobicContact CD1-CG1 4.32Å; F138-I142 HydrophobicContact CE1-CD1 4.41Å; F138-I142 HydrophobicContact CE1-CG1 3.79Å; F138-I142 HydrophobicContact CE2-CD1 4.1Å; F138-I142 HydrophobicContact CE2-CG1 3.98Å; F138-I142 HydrophobicContact CZ-CD1 3.77Å; F138-I142 HydrophobicContact CZ-CG1 3.6Å; F138-I142 WeakPolarHBondContact O-CG1 3.33Å; F138-I142 PolarHBondContact O-N 2.93Å; F138-F153 HydrophobicContact CE2-CD1 4.3Å; F138-F153 AromaticContact CE2-CE1 3.64Å; F138-F153 HydrophobicContact CE2-CE1 3.64Å; F138-F153 HydrophobicContact CE2-CZ 4.41Å; F138-F153 HydrophobicContact CZ-CD1 4.49Å; F138-F153 HydrophobicContact CZ-CE1 4.18Å
139	L	97.6	Very high	97	Very high	8 Å²	8	52.3 Å²	52.3	4%	0.042	26%	0.262	C	S	.	.	H	α-helix	trans	-61.6	-43.4	176	-70.7	173.8	0	0	0	111.4	Y135 E136 F141 I142 L143 I388 T391 E392 I395	Y135-L139 HydrophobicContact CD1-CD1 4.02Å; Y135-L139 HydrophobicContact CD2-CD1 4.48Å; Y135-L139 HydrophobicContact CD2-CG 4.25Å; Y135-L139 HydrophobicContact CE1-CD1 3.67Å; Y135-L139 HydrophobicContact CE1-CG 4.35Å; Y135-L139 HydrophobicContact CE2-CD1 4.17Å; Y135-L139 HydrophobicContact CE2-CD2 3.95Å; Y135-L139 HydrophobicContact CE2-CG 3.94Å; Y135-L139 HydrophobicContact CG-CD1 4.41Å; Y135-L139 WeakPolarHBondContact O-CG 3.31Å; Y135-L139 PolarHBondContact O-N 3.32Å; E136-L139 PolarHBondContact O-N 3.34Å; L139-F141 VanDerWaalsContact C-N 3.32Å; L139-F141 PolarHBondContact O-N 3.29Å; L139-I142 PolarHBondContact O-N 3.38Å; L139-L143 WeakPolarHBondContact O-CB 3.38Å; L139-L143 PolarHBondContact O-N 3.26Å; L139-I388 HydrophobicContact CD1-CB 4.42Å; L139-I388 HydrophobicContact CD1-CG1 4.47Å; L139-I388 HydrophobicContact CD1-CG2 3.84Å; L139-T391 HydrophobicContact CB-CG2 3.69Å; L139-E392 HydrophobicContact CD1-CG 3.64Å; L139-E392 HydrophobicContact CD2-CG 4.06Å; L139-I395 HydrophobicContact CB-CD1 4.03Å; L139-I395 HydrophobicContact CD2-CD1 3.72Å; L139-I395 HydrophobicContact CG-CD1 4.47Å; L139-I395 WeakPolarHBondContact O-CD1 3.26Å
140	I	97.9	Very high	96.9	Very high	64 Å²	64	50.8 Å²	50.8	33%	0.328	25%	0.254	S	S	.	.	H	α-helix	trans	-58.7	-45.6	173.8	-68	166.8	0	0	0	110.2	E136 F138 I142 L143 F144 T391	E136-I140 HydrophobicContact CG-CD1 4.03Å; E136-I140 VanDerWaalsContact O-CG1 3.3Å; E136-I140 WeakPolarHBondContact O-CG1 3.09Å; E136-I140 PolarHBondContact O-N 2.89Å; F138-I140 VanDerWaalsContact C-N 3.35Å; F138-I140 PolarHBondContact O-N 3.38Å; I140-I142 PolarHBondContact O-N 3.1Å; I140-L143 WeakPolarHBondContact O-CB 3.29Å; I140-L143 PolarHBondContact O-N 3.16Å; I140-F144 HydrophobicContact CG2-CD2 4Å; I140-F144 HydrophobicContact CG2-CE2 3.82Å; I140-F144 WeakPolarHBondContact O-CD2 3.4Å; I140-F144 PolarHBondContact O-N 3.22Å; I140-T391 HydrophobicContact CG1-CG2 4.22Å
141	F	96.7	Very high	96.8	Very high	82 Å²	82	52.1 Å²	52.1	36%	0.36	26%	0.258	S	S	.	.	H	α-helix	trans	-57.1	-47.1	175.7	169	-94.3	0	0	0	112.4	L137 F138 L139 L143 F144 Q145 F153	L137-F141 PolarHBondContact O-N 3.03Å; F138-F141 HydrophobicContact CE2-CD1 4.49Å; F138-F141 WeakPolarHBondContact O-CB 3.32Å; F138-F141 PolarHBondContact O-N 3.12Å; L139-F141 VanDerWaalsContact C-N 3.32Å; L139-F141 PolarHBondContact O-N 3.29Å; F141-L143 VanDerWaalsContact C-N 3.33Å; F141-L143 PolarHBondContact O-N 3.49Å; F141-F144 PolarHBondContact O-N 2.9Å; F141-Q145 HydrophobicContact CE1-CG 4.17Å; F141-Q145 HydrophobicContact CZ-CG 4.35Å; F141-Q145 WeakPolarHBondContact O-CG 3.31Å; F141-Q145 PolarHBondContact O-N 3.22Å; F141-Q145 PolarHBondContact O-NE2 3.24Å; F141-Q145 VanDerWaalsContact O-NE2 3.11Å; F141-F153 HydrophobicContact CD1-CZ 4.49Å; F141-F153 HydrophobicContact CE1-CD1 4.19Å; F141-F153 AromaticContact CE1-CD2 3.66Å; F141-F153 HydrophobicContact CE1-CD2 3.66Å; F141-F153 HydrophobicContact CE1-CE1 4.07Å; F141-F153 AromaticContact CE1-CE2 3.46Å; F141-F153 HydrophobicContact CE1-CE2 3.46Å; F141-F153 VanDerWaalsContact CE1-CE2 3.46Å; F141-F153 HydrophobicContact CE1-CG 4.02Å; F141-F153 AromaticContact CE1-CZ 3.68Å; F141-F153 HydrophobicContact CE1-CZ 3.68Å; F141-F153 AromaticContact CZ-CD2 3.88Å; F141-F153 HydrophobicContact CZ-CD2 3.88Å; F141-F153 AromaticContact CZ-CE2 3.63Å; F141-F153 HydrophobicContact CZ-CE2 3.63Å; F141-F153 HydrophobicContact CZ-CZ 4.23Å
142	I	96.5	Very high	96.6	Very high	4 Å²	4	54.2 Å²	54.2	2%	0.021	27%	0.266	C	S	.	.	H	α-helix	trans	-63.1	-39	176.6	-68.4	-63.7	0	0	0	111.4	F138 L139 I140 F144 Q145 F153 L338 I395 Y399	F138-I142 HydrophobicContact CD1-CG1 4.32Å; F138-I142 HydrophobicContact CE1-CD1 4.41Å; F138-I142 HydrophobicContact CE1-CG1 3.79Å; F138-I142 HydrophobicContact CE2-CD1 4.1Å; F138-I142 HydrophobicContact CE2-CG1 3.98Å; F138-I142 HydrophobicContact CZ-CD1 3.77Å; F138-I142 HydrophobicContact CZ-CG1 3.6Å; F138-I142 WeakPolarHBondContact O-CG1 3.33Å; F138-I142 PolarHBondContact O-N 2.93Å; L139-I142 PolarHBondContact O-N 3.38Å; I140-I142 PolarHBondContact O-N 3.1Å; I142-F144 PolarHBondContact O-N 2.86Å; I142-Q145 WeakPolarHBondContact O-CB 3.38Å; I142-Q145 PolarHBondContact O-N 2.8Å; I142-F153 HydrophobicContact CD1-CD1 3.97Å; I142-F153 HydrophobicContact CD1-CG 4.47Å; I142-L338 HydrophobicContact CG2-CD2 4.45Å; I142-I395 HydrophobicContact CB-CD1 4.41Å; I142-I395 HydrophobicContact CG2-CD1 4.14Å; I142-I395 HydrophobicContact CG2-CG2 4.26Å; I142-Y399 WeakPolarHBondContact CG2-OH 3.27Å; I142-Y399 PolarHBondContact O-OH 2.84Å
143	L	97.3	Very high	96.3	Very high	37 Å²	37	56.8 Å²	56.8	19%	0.194	28%	0.277	C	S	.	.	H	α-helix	trans	-59.1	-31.6	176.6	-179.5	66.7	0	0	0	111.9	L139 I140 F141 T391 L394 I395 K398	L139-L143 WeakPolarHBondContact O-CB 3.38Å; L139-L143 PolarHBondContact O-N 3.26Å; I140-L143 WeakPolarHBondContact O-CB 3.29Å; I140-L143 PolarHBondContact O-N 3.16Å; F141-L143 VanDerWaalsContact C-N 3.33Å; F141-L143 PolarHBondContact O-N 3.49Å; L143-T391 HydrophobicContact CD2-CG2 4.38Å; L143-L394 HydrophobicContact CD1-CB 3.96Å; L143-I395 HydrophobicContact CB-CD1 4.45Å; L143-I395 HydrophobicContact CB-CG1 3.86Å; L143-I395 HydrophobicContact CD1-CG1 3.83Å; L143-I395 HydrophobicContact CG-CG1 4.44Å; L143-K398 HydrophobicContact CD1-CD 4.26Å; L143-K398 WeakPolarHBondContact O-CD 3.33Å; L143-K398 PolarHBondContact O-NZ 2.93Å
144	F	97.2	Very high	96	Very high	162 Å²	162	54.8 Å²	54.8	71%	0.711	27%	0.265	S	S	*	.	H	α-helix	trans	-82.9	-12.4	176.5	-79.2	-77.8	0	0	0	114.5	I140 F141 I142	I140-F144 HydrophobicContact CG2-CD2 4Å; I140-F144 HydrophobicContact CG2-CE2 3.82Å; I140-F144 WeakPolarHBondContact O-CD2 3.4Å; I140-F144 PolarHBondContact O-N 3.22Å; F141-F144 PolarHBondContact O-N 2.9Å; I142-F144 PolarHBondContact O-N 2.86Å
145	Q	96.5	Very high	95.6	Very high	45 Å²	45	57.3 Å²	57.3	21%	0.21	27%	0.273	C	S	.	.	S	Bend	trans	-74.8	157.2	176.6	-54.8	-48.3	-57.7	0	0	112.1	F141 I142 D149 K398	F141-Q145 HydrophobicContact CE1-CG 4.17Å; F141-Q145 HydrophobicContact CZ-CG 4.35Å; F141-Q145 WeakPolarHBondContact O-CG 3.31Å; F141-Q145 PolarHBondContact O-N 3.22Å; F141-Q145 PolarHBondContact O-NE2 3.24Å; F141-Q145 VanDerWaalsContact O-NE2 3.11Å; I142-Q145 WeakPolarHBondContact O-CB 3.38Å; I142-Q145 PolarHBondContact O-N 2.8Å; Q145-D149 HydrophobicContact CB-CB 4.19Å; Q145-K398 PolarHBondContact O-NZ 3.27Å
146	T	96.1	Very high	95.2	Very high	70 Å²	70	61.7 Å²	61.7	43%	0.429	29%	0.291	S	S	.	.			trans	-67.6	163.1	161.6	73.5	0	0	0	0	109.6	Q148 D149 G150	T146-Q148 VanDerWaalsContact C-N 3.28Å; T146-Q148 PolarHBondContact O-N 2.91Å; T146-D149 WeakPolarHBondContact CG2-OD2 3.37Å; T146-D149 PolarHBondContact O-N 3.42Å; T146-D149 VanDerWaalsContact OG1-CB 3.32Å; T146-D149 WeakPolarHBondContact OG1-CB 3.43Å; T146-D149 PolarHBondContact OG1-N 3.12Å; T146-D149 VanDerWaalsContact OG1-N 3.07Å; T146-D149 PolarHBondContact OG1-OD2 2.83Å; T146-G150 PolarHBondContact O-N 3.12Å
147	V	94.6	Very high	94.7	Very high	28 Å²	28	63.2 Å²	63.2	17%	0.17	30%	0.301	C	S	.	.	H	α-helix	trans	-58.5	-44.2	-179.7	-177.3	0	0	0	0	111	R151 Y399	V147-R151 VanDerWaalsContact CG1-CZ 3.43Å; V147-R151 WeakPolarHBondContact O-CB 3.4Å; V147-R151 WeakPolarHBondContact O-CD 3.45Å; V147-R151 VanDerWaalsContact O-CG 3.26Å; V147-R151 WeakPolarHBondContact O-CG 3.46Å; V147-R151 PolarHBondContact O-N 3.36Å; V147-R151 VanDerWaalsContact O-N 3.09Å; V147-Y399 HydrophobicContact CB-CD2 4.18Å; V147-Y399 HydrophobicContact CB-CE2 4.5Å; V147-Y399 HydrophobicContact CG1-CD2 3.8Å; V147-Y399 HydrophobicContact CG1-CE2 4.41Å; V147-Y399 HydrophobicContact CG1-CG 4.31Å; V147-Y399 HydrophobicContact CG2-CD1 4.47Å; V147-Y399 HydrophobicContact CG2-CD2 4.25Å; V147-Y399 HydrophobicContact CG2-CG 4.08Å
148	Q	94.7	Very high	94.3	Very high	124 Å²	124	59.6 Å²	59.6	58%	0.579	28%	0.282	S	S	*	.	H	α-helix	trans	-66.7	-47.5	178.6	-70	76.5	0.1	0	0	110.7	T146 G150 R151 Q152	T146-Q148 VanDerWaalsContact C-N 3.28Å; T146-Q148 PolarHBondContact O-N 2.91Å; Q148-G150 VanDerWaalsContact C-N 3.35Å; Q148-G150 PolarHBondContact O-N 3.4Å; Q148-R151 PolarHBondContact O-N 2.86Å; Q148-Q152 WeakPolarHBondContact O-CB 3.27Å; Q148-Q152 WeakPolarHBondContact O-CG 3.49Å; Q148-Q152 PolarHBondContact O-N 2.97Å
149	D	95.4	Very high	94.1	Very high	84 Å²	84	61.4 Å²	61.4	45%	0.449	30%	0.301	S	S	.	.	H	α-helix	trans	-63.8	-40.6	179.7	-64	-34.9	0	0	0	111.5	Q145 T146 Q152 F153	Q145-D149 HydrophobicContact CB-CB 4.19Å; T146-D149 WeakPolarHBondContact CG2-OD2 3.37Å; T146-D149 PolarHBondContact O-N 3.42Å; T146-D149 VanDerWaalsContact OG1-CB 3.32Å; T146-D149 WeakPolarHBondContact OG1-CB 3.43Å; T146-D149 PolarHBondContact OG1-N 3.12Å; T146-D149 VanDerWaalsContact OG1-N 3.07Å; T146-D149 PolarHBondContact OG1-OD2 2.83Å; D149-Q152 PolarHBondContact O-N 3.18Å; D149-F153 WeakPolarHBondContact O-CA 3.48Å; D149-F153 WeakPolarHBondContact O-CB 3.38Å; D149-F153 PolarHBondContact O-N 2.93Å
150	G	94.5	Very high	93.7	Very high	0 Å²	0	69.1 Å²	69.1	0%	0	33%	0.334	C	S	.	.	H	α-helix	trans	-61.9	-44.1	175.6	0	0	0	0	0	112.6	T146 Q148 F153 L154	T146-G150 PolarHBondContact O-N 3.12Å; Q148-G150 VanDerWaalsContact C-N 3.35Å; Q148-G150 PolarHBondContact O-N 3.4Å; G150-F153 WeakPolarHBondContact O-CB 3.39Å; G150-F153 PolarHBondContact O-N 3.21Å; G150-L154 PolarHBondContact O-N 2.93Å
151	R	94.9	Very high	93.5	Very high	34 Å²	34	66.2 Å²	66.2	13%	0.128	32%	0.319	C	S	.	.	H	α-helix	trans	-64.3	-44.4	175.1	-73.6	167.5	176.3	167.6	5.1	112.1	V147 Q148 F153 L154 G162 V337 W339	V147-R151 VanDerWaalsContact CG1-CZ 3.43Å; V147-R151 WeakPolarHBondContact O-CB 3.4Å; V147-R151 WeakPolarHBondContact O-CD 3.45Å; V147-R151 VanDerWaalsContact O-CG 3.26Å; V147-R151 WeakPolarHBondContact O-CG 3.46Å; V147-R151 PolarHBondContact O-N 3.36Å; V147-R151 VanDerWaalsContact O-N 3.09Å; Q148-R151 PolarHBondContact O-N 2.86Å; R151-F153 VanDerWaalsContact C-N 3.33Å; R151-L154 PolarHBondContact O-N 3.45Å; R151-G162 VanDerWaalsContact O-CA 3.3Å; R151-G162 WeakPolarHBondContact O-CA 3.24Å; R151-V337 VanDerWaalsContact CZ-O 3.3Å; R151-V337 PolarHBondContact NE-O 3.34Å; R151-V337 PolarHBondContact NH2-O 2.94Å; R151-W339 HydrophobicContact CB-CE3 4.32Å; R151-W339 HydrophobicContact CG-CD2 4.35Å; R151-W339 HydrophobicContact CG-CE3 4.2Å; R151-W339 VanDerWaalsContact CZ-CE2 3.45Å
152	Q	94.3	Very high	93.2	Very high	75 Å²	75	62.5 Å²	62.5	35%	0.35	30%	0.304	S	S	.	.	H	α-helix	trans	-70.8	-30.9	178.1	-65.6	-47.4	-60.8	0	0	111.9	Q148 D149 L154 K155 G162	Q148-Q152 WeakPolarHBondContact O-CB 3.27Å; Q148-Q152 WeakPolarHBondContact O-CG 3.49Å; Q148-Q152 PolarHBondContact O-N 2.97Å; D149-Q152 PolarHBondContact O-N 3.18Å; Q152-L154 PolarHBondContact O-N 3.29Å; Q152-K155 VanDerWaalsContact O-CB 3.24Å; Q152-K155 WeakPolarHBondContact O-CB 3.21Å; Q152-K155 PolarHBondContact O-N 3.26Å; Q152-G162 PolarHBondContact NE2-O 3.49Å
153	F	92.1	Very high	92.9	Very high	53 Å²	53	65.6 Å²	65.6	23%	0.232	32%	0.324	C	S	.	.	H	α-helix	trans	-59.4	-35.4	175.8	-177.1	-84.6	0	0	0	111.4	F138 F141 I142 D149 G150 R151 K155 Y156	F138-F153 HydrophobicContact CE2-CD1 4.3Å; F138-F153 AromaticContact CE2-CE1 3.64Å; F138-F153 HydrophobicContact CE2-CE1 3.64Å; F138-F153 HydrophobicContact CE2-CZ 4.41Å; F138-F153 HydrophobicContact CZ-CD1 4.49Å; F138-F153 HydrophobicContact CZ-CE1 4.18Å; F141-F153 HydrophobicContact CD1-CZ 4.49Å; F141-F153 HydrophobicContact CE1-CD1 4.19Å; F141-F153 AromaticContact CE1-CD2 3.66Å; F141-F153 HydrophobicContact CE1-CD2 3.66Å; F141-F153 HydrophobicContact CE1-CE1 4.07Å; F141-F153 AromaticContact CE1-CE2 3.46Å; F141-F153 HydrophobicContact CE1-CE2 3.46Å; F141-F153 VanDerWaalsContact CE1-CE2 3.46Å; F141-F153 HydrophobicContact CE1-CG 4.02Å; F141-F153 AromaticContact CE1-CZ 3.68Å; F141-F153 HydrophobicContact CE1-CZ 3.68Å; F141-F153 AromaticContact CZ-CD2 3.88Å; F141-F153 HydrophobicContact CZ-CD2 3.88Å; F141-F153 AromaticContact CZ-CE2 3.63Å; F141-F153 HydrophobicContact CZ-CE2 3.63Å; F141-F153 HydrophobicContact CZ-CZ 4.23Å; I142-F153 HydrophobicContact CD1-CD1 3.97Å; I142-F153 HydrophobicContact CD1-CG 4.47Å; D149-F153 WeakPolarHBondContact O-CA 3.48Å; D149-F153 WeakPolarHBondContact O-CB 3.38Å; D149-F153 PolarHBondContact O-N 2.93Å; G150-F153 WeakPolarHBondContact O-CB 3.39Å; G150-F153 PolarHBondContact O-N 3.21Å; R151-F153 VanDerWaalsContact C-N 3.33Å; F153-K155 PolarHBondContact O-N 3.39Å; F153-Y156 HydrophobicContact CD2-CD2 4.25Å; F153-Y156 WeakPolarHBondContact O-CB 3.42Å; F153-Y156 WeakPolarHBondContact O-CD2 3.47Å; F153-Y156 PolarHBondContact O-N 3.31Å
154	L	91.4	Very high	92.5	Very high	6 Å²	6	68.3 Å²	68.3	3%	0.031	34%	0.343	C	S	.	.	G	3₁₀ helix	trans	-60.2	-19	176.7	-66.8	-177.7	0	0	0	113.7	G150 R151 Q152 Y156 V157 D158 L161 L338 M340	G150-L154 PolarHBondContact O-N 2.93Å; R151-L154 PolarHBondContact O-N 3.45Å; Q152-L154 PolarHBondContact O-N 3.29Å; L154-Y156 PolarHBondContact O-N 2.83Å; L154-V157 WeakPolarHBondContact O-CA 3.3Å; L154-V157 WeakPolarHBondContact O-CB 3.35Å; L154-V157 PolarHBondContact O-N 2.97Å; L154-D158 PolarHBondContact O-N 3.43Å; L154-L161 HydrophobicContact CB-CB 3.91Å; L154-L161 HydrophobicContact CB-CD1 3.89Å; L154-L161 HydrophobicContact CD1-CD1 4.48Å; L154-L338 HydrophobicContact CD1-CB 3.82Å; L154-L338 HydrophobicContact CD1-CD1 4.47Å; L154-L338 HydrophobicContact CD1-CD2 4.45Å; L154-L338 HydrophobicContact CD1-CG 4.48Å; L154-M340 HydrophobicContact CD1-CG 4.05Å; L154-M340 HydrophobicContact CD1-SD 4.23Å
155	K	90.9	Very high	91.8	Very high	83 Å²	83	63.8 Å²	63.8	36%	0.361	33%	0.326	S	S	.	.	G	3₁₀ helix	trans	-63.9	-25.2	172.5	-67.9	-179.1	171.5	174.6	0	113.8	Q152 F153 V157 D158 L161	Q152-K155 VanDerWaalsContact O-CB 3.24Å; Q152-K155 WeakPolarHBondContact O-CB 3.21Å; Q152-K155 PolarHBondContact O-N 3.26Å; F153-K155 PolarHBondContact O-N 3.39Å; K155-V157 PolarHBondContact O-N 2.9Å; K155-D158 WeakPolarHBondContact CA-O 3.26Å; K155-D158 CarbonylContact O-C 3.52Å; K155-L161 WeakPolarHBondContact CE-O 3.39Å; K155-L161 WeakPolarHBondContact CG-O 3.36Å
156	Y	87.8	Confident	91	Very high	139 Å²	139	66.5 Å²	66.5	55%	0.545	35%	0.348	S	S	.	.	G	3₁₀ helix	trans	-69.4	-23.8	172.8	-71.3	-80.2	0	0	0	112.3	A90 K94 F153 L154	A90-Y156 HydrophobicContact CB-CE1 4.5Å; K94-Y156 PolarHBondContact NZ-O 3.5Å; F153-Y156 HydrophobicContact CD2-CD2 4.25Å; F153-Y156 WeakPolarHBondContact O-CB 3.42Å; F153-Y156 WeakPolarHBondContact O-CD2 3.47Å; F153-Y156 PolarHBondContact O-N 3.31Å; L154-Y156 PolarHBondContact O-N 2.83Å
157	V	88.4	Confident	89.6	Confident	52 Å²	52	70.1 Å²	70.1	32%	0.315	36%	0.36	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.3	-58.6	176.2	-176.5	0	0	0	0	109.9	L154 K155 Y345 L346	L154-V157 WeakPolarHBondContact O-CA 3.3Å; L154-V157 WeakPolarHBondContact O-CB 3.35Å; L154-V157 PolarHBondContact O-N 2.97Å; K155-V157 PolarHBondContact O-N 2.9Å; V157-Y345 WeakPolarHBondContact CG1-OH 3.39Å; V157-L346 HydrophobicContact CG1-CD1 4.03Å; V157-L346 HydrophobicContact CG1-CD2 4.11Å
158	D	90.2	Very high	88.3	Confident	30 Å²	30	74.9 Å²	74.9	16%	0.16	38%	0.375	C	S	.	.			trans	-134.7	120	172.9	-174.8	-28.7	0	0	0	109.6	L154 K155 K160 L161 H344 Y345	L154-D158 PolarHBondContact O-N 3.43Å; K155-D158 WeakPolarHBondContact CA-O 3.26Å; K155-D158 CarbonylContact O-C 3.52Å; D158-K160 PolarHBondContact O-N 2.79Å; D158-K160 WeakPolarHBondContact OD1-CB 3.46Å; D158-K160 WeakPolarHBondContact OD1-CG 3.45Å; D158-K160 PolarHBondContact OD1-N 3.23Å; D158-L161 HydrophobicContact CB-CD1 3.95Å; D158-L161 HydrophobicContact CB-CG 4.05Å; D158-L161 WeakPolarHBondContact O-CB 3.41Å; D158-L161 PolarHBondContact O-N 3.44Å; D158-H344 IonicContact OD2-NE2 2.68Å; D158-H344 PolarHBondContact OD2-NE2 3.24Å; D158-Y345 HydrophobicContact CB-CE1 4.42Å
159	P	90.3	Very high	87.1	Confident	109 Å²	109	74.2 Å²	74.2	71%	0.708	37%	0.371	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.3	-20.4	179.3	-26.1	34.7	0	0	0	115.6	L161	P159-L161 VanDerWaalsContact C-N 3.32Å
160	K	90.8	Very high	85.7	Confident	170 Å²	170	74.5 Å²	74.5	74%	0.739	37%	0.367	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.5	-12.6	179	-62.4	177.3	-178.6	176.6	0	113.7	D158	D158-K160 PolarHBondContact O-N 2.79Å; D158-K160 WeakPolarHBondContact OD1-CB 3.46Å; D158-K160 WeakPolarHBondContact OD1-CG 3.45Å; D158-K160 PolarHBondContact OD1-N 3.23Å
161	L	92.7	Very high	84.3	Confident	3 Å²	3	75.7 Å²	75.7	2%	0.016	38%	0.379	C	S	.	.			trans	-82	175.5	179.9	-67	175	0	0	0	112.5	L154 K155 D158 P159 V163 M340 L346	L154-L161 HydrophobicContact CB-CB 3.91Å; L154-L161 HydrophobicContact CB-CD1 3.89Å; L154-L161 HydrophobicContact CD1-CD1 4.48Å; K155-L161 WeakPolarHBondContact CE-O 3.39Å; K155-L161 WeakPolarHBondContact CG-O 3.36Å; D158-L161 HydrophobicContact CB-CD1 3.95Å; D158-L161 HydrophobicContact CB-CG 4.05Å; D158-L161 WeakPolarHBondContact O-CB 3.41Å; D158-L161 PolarHBondContact O-N 3.44Å; P159-L161 VanDerWaalsContact C-N 3.32Å; L161-V163 VanDerWaalsContact C-N 3.3Å; L161-V163 PolarHBondContact O-N 3.1Å; L161-M340 HydrophobicContact CD2-CG 4.24Å; L161-L346 HydrophobicContact CD1-CD1 3.89Å
162	G	90.1	Very high	83.3	Confident	4 Å²	4	77 Å²	77	4%	0.041	40%	0.403	C	S	.	.	S	Bend	trans	73.4	23.8	177.6	0	0	0	0	0	113.6	R151 Q152	R151-G162 VanDerWaalsContact O-CA 3.3Å; R151-G162 WeakPolarHBondContact O-CA 3.24Å; Q152-G162 PolarHBondContact NE2-O 3.49Å
163	V	90.9	Very high	82.4	Confident	70 Å²	70	76.8 Å²	76.8	42%	0.424	40%	0.404	S	S	.	.	S	Bend	trans	-118.4	141.8	171.5	-62.4	0	0	0	0	109.6	L161 W339	L161-V163 VanDerWaalsContact C-N 3.3Å; L161-V163 PolarHBondContact O-N 3.1Å; V163-W339 VanDerWaalsContact O-CB 3.31Å; V163-W339 WeakPolarHBondContact O-CB 3.42Å
164	P	87.7	Confident	81.9	Confident	94 Å²	94	76 Å²	76	61%	0.61	41%	0.405	S	S	*	.	P	Polyproline II helix	trans	-57	140.4	175.7	-21.2	30.5	0	0	0	111.6	W339	P164-W339 HydrophobicContact CB-CH2 4.49Å; P164-W339 HydrophobicContact CB-CZ2 4.26Å; P164-W339 HydrophobicContact CG-CE3 4.34Å; P164-W339 HydrophobicContact CG-CH2 3.67Å; P164-W339 HydrophobicContact CG-CZ2 3.88Å; P164-W339 HydrophobicContact CG-CZ3 3.91Å
165	L	84.6	Confident	81.5	Confident	66 Å²	66	79.5 Å²	79.5	35%	0.346	42%	0.423	S	S	.	.	P	Polyproline II helix	trans	-98.3	147.3	176.9	-62.8	173.2	0	0	0	110.3	W339 M340 P341	L165-W339 HydrophobicContact CG-CB 4.46Å; L165-M340 VanDerWaalsContact CD1-C 3.42Å; L165-M340 WeakPolarHBondContact CD1-O 3.21Å; L165-P341 HydrophobicContact CD1-CG 4.28Å; L165-P341 HydrophobicContact CD2-CG 3.91Å
166	P	78.9	Confident	81.2	Confident	102 Å²	102	79 Å²	79	66%	0.662	42%	0.424	S	S	*	.	P	Polyproline II helix	trans	-63.9	138.6	170.8	28.2	-33.3	0	0	0	109.8	R168	P166-R168 PolarHBondContact O-N 3.32Å
167	E	66.8	Low	81.1	Confident	146 Å²	146	78.5 Å²	78.5	68%	0.682	42%	0.422	S	S	*	.	P	Polyproline II helix	trans	-66.3	127.2	171.4	-67.2	179.1	-179.1	0	0	108.9
168	R	67.1	Low	81	Confident	129 Å²	129	76.7 Å²	76.7	49%	0.487	41%	0.411	S	S	.	.			trans	-113.4	126.3	173.5	-72.7	-173	177.5	174.3	-1.3	108.2	P166 P236 N237	P166-R168 PolarHBondContact O-N 3.32Å; R168-P236 CarbonylContact O-C 3.45Å; R168-N237 PolarHBondContact O-N 3.29Å; R168-N237 PolarHBondContact O-OD1 3.18Å
169	H	68.4	Low	80.7	Confident	110 Å²	110	78.9 Å²	78.9	51%	0.509	43%	0.427	S	S	.	.			trans	-107.1	132.6	167.1	-62.1	-90.1	0	0	0	107.5	P236	H169-P236 WeakPolarHBondContact CE1-CB 3.39Å; H169-P236 WeakPolarHBondContact ND1-CB 3.39Å
170	Y	67.2	Low	80.4	Confident	90 Å²	90	80.6 Å²	80.6	35%	0.353	43%	0.43	S	S	.	.			trans	-96.4	-11.9	175.6	-57.5	-78.5	0	0	0	112.1	N237 S239	Y170-N237 WeakPolarHBondContact CD2-O 2.85Å; Y170-N237 HydrophobicContact CE2-CB 4.25Å; Y170-S239 CarbonylContact C-O 3.28Å; Y170-S239 VanDerWaalsContact C-O 3.28Å; Y170-S239 WeakPolarHBondContact CA-O 3.33Å; Y170-S239 PolarHBondContact N-O 3.17Å
171	G	63.9	Low	80	Confident	24 Å²	24	74.6 Å²	74.6	25%	0.247	41%	0.406	C	S	.	.			trans	-88.6	132.6	175.4	0	0	0	0	0	110.9	S239	G171-S239 WeakPolarHBondContact CA-O 3.44Å; G171-S239 PolarHBondContact N-O 3.46Å
172	G	74.7	Confident	79.5	Confident	63 Å²	63	83.4 Å²	83.4	65%	0.649	45%	0.447	S	S	*	.	S	Bend	trans	-170.6	-117.9	-175.3	0	0	0	0	0	110.4	C174	G172-C174 PolarHBondContact O-N 3.42Å; G172-C174 VanDerWaalsContact O-N 3.11Å
173	N	75.3	Confident	79.2	Confident	69 Å²	69	89.6 Å²	89.6	37%	0.369	48%	0.484	S	S	.	.			trans	-72.4	101.7	171.2	-171.8	5	0	0	0	110.1	L175 D178 N188	N173-L175 PolarHBondContact O-N 3.34Å; N173-L175 WeakPolarHBondContact OD1-CB 3.02Å; N173-L175 WeakPolarHBondContact OD1-CD1 3.35Å; N173-L175 WeakPolarHBondContact OD1-CG 3.49Å; N173-L175 PolarHBondContact OD1-N 3.01Å; N173-D178 PolarHBondContact ND2-OD2 3.45Å; N173-N188 PolarHBondContact O-ND2 2.68Å; N173-N188 VanDerWaalsContact O-ND2 3.1Å
174	C	81.9	Confident	78.8	Confident	38 Å²	38	88.8 Å²	88.8	26%	0.257	48%	0.478	S	S	.	.			trans	-89.1	18.6	-178.6	-67.6	0	0	0	0	114.5	G172 I176 C241 W243	G172-C174 PolarHBondContact O-N 3.42Å; G172-C174 VanDerWaalsContact O-N 3.11Å; C174-I176 PolarHBondContact O-N 3.29Å; C174-C241 WeakPolarHBondContact CA-SG 3.38Å; C174-C241 HydrophobicContact CB-CB 3.67Å; C174-C241 WeakPolarHBondContact CB-SG 3.07Å; C174-C241 WeakPolarHBondContact SG-CA 3.31Å; C174-C241 WeakPolarHBondContact SG-CB 3.43Å; C174-C241 CovalentContact SG-SG 2.06Å; C174-C241 PolarHBondContact SG-SG 3.19Å; C174-W243 PolarHBondContact O-NE1 3.09Å
175	L	83.1	Confident	78.7	Confident	78 Å²	78	85.8 Å²	85.8	41%	0.408	46%	0.458	S	S	.	.			trans	-70.1	121.5	171.3	-66.2	175.8	0	0	0	109.9	N173 Y177 N188	N173-L175 PolarHBondContact O-N 3.34Å; N173-L175 WeakPolarHBondContact OD1-CB 3.02Å; N173-L175 WeakPolarHBondContact OD1-CD1 3.35Å; N173-L175 WeakPolarHBondContact OD1-CG 3.49Å; N173-L175 PolarHBondContact OD1-N 3.01Å; L175-Y177 VanDerWaalsContact C-N 3.26Å; L175-N188 PolarHBondContact O-ND2 3.11Å
176	I	83.8	Confident	78.8	Confident	74 Å²	74	86.9 Å²	86.9	38%	0.379	46%	0.46	S	S	.	.	S	Bend	trans	-64	-38.6	172.3	-65.2	174	0	0	0	110.1	C174 F186 V189 W243	C174-I176 PolarHBondContact O-N 3.29Å; I176-F186 HydrophobicContact CG2-CE1 4.5Å; I176-F186 WeakPolarHBondContact O-CD1 3.47Å; I176-V189 HydrophobicContact CG2-CG2 4.04Å; I176-W243 HydrophobicContact CD1-CB 4.16Å; I176-W243 HydrophobicContact CD1-CD2 4.21Å; I176-W243 HydrophobicContact CD1-CG 3.88Å; I176-W243 HydrophobicContact CG1-CD2 3.84Å; I176-W243 HydrophobicContact CG1-CG 3.81Å; I176-W243 HydrophobicContact CG1-CZ2 4.43Å
177	Y	86.5	Confident	79	Confident	127 Å²	127	83.7 Å²	83.7	50%	0.498	44%	0.436	S	S	.	.	S	Bend	trans	-120.6	112	172.1	177.5	-96.3	0	0	0	107.3	L175 P179 P185 F186	L175-Y177 VanDerWaalsContact C-N 3.26Å; Y177-P179 HydrophobicContact CD1-CB 4.46Å; Y177-P179 HydrophobicContact CE1-CB 4.01Å; Y177-P179 VanDerWaalsContact O-CD 3.24Å; Y177-P179 WeakPolarHBondContact O-CD 3.42Å; Y177-P185 CarbonylContact C-O 3.31Å; Y177-P185 WeakPolarHBondContact CA-O 3.37Å; Y177-P185 HydrophobicContact CD2-CB 3.58Å; Y177-P185 HydrophobicContact CE2-CB 3.27Å; Y177-P185 HydrophobicContact CE2-CG 3.98Å; Y177-P185 HydrophobicContact CG-CB 4.46Å; Y177-F186 HydrophobicContact CD2-CD2 4.35Å; Y177-F186 HydrophobicContact CD2-CE1 4.03Å; Y177-F186 AromaticContact CD2-CE2 3.76Å; Y177-F186 HydrophobicContact CD2-CE2 3.76Å; Y177-F186 AromaticContact CD2-CZ 3.59Å; Y177-F186 HydrophobicContact CD2-CZ 3.59Å; Y177-F186 HydrophobicContact CE2-CE2 4.16Å; Y177-F186 HydrophobicContact CE2-CZ 4.35Å; Y177-F186 HydrophobicContact CG-CZ 4.49Å
178	D	85.5	Confident	79.7	Confident	14 Å²	14	78.2 Å²	78.2	8%	0.075	41%	0.412	C	S	.	.			trans	-91.9	102.6	176.1	-170.9	-5.2	0	0	0	109.6	N173 D180 N181 P185 H187	N173-D178 PolarHBondContact ND2-OD2 3.45Å; D178-D180 PolarHBondContact O-N 2.82Å; D178-D180 WeakPolarHBondContact OD1-CB 3.03Å; D178-D180 PolarHBondContact OD1-N 3.03Å; D178-N181 HydrophobicContact CB-CB 4.37Å; D178-N181 PolarHBondContact O-N 3.38Å; D178-P185 PolarHBondContact N-O 3.26Å; D178-P185 WeakPolarHBondContact O-CA 3.47Å; D178-H187 IonicContact OD2-CE1 3.44Å; D178-H187 PolarHBondContact OD2-CE1 3.44Å; D178-H187 VanDerWaalsContact OD2-CE1 3.27Å; D178-H187 IonicContact OD2-NE2 3.71Å
179	P	83.7	Confident	80.4	Confident	77 Å²	77	73.6 Å²	73.6	50%	0.5	40%	0.398	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.9	-18	178.9	30.7	-35.3	0	0	0	112.7	Y177	Y177-P179 HydrophobicContact CD1-CB 4.46Å; Y177-P179 HydrophobicContact CE1-CB 4.01Å; Y177-P179 VanDerWaalsContact O-CD 3.24Å; Y177-P179 WeakPolarHBondContact O-CD 3.42Å
180	D	84	Confident	81.1	Confident	145 Å²	145	75.7 Å²	75.7	78%	0.775	40%	0.401	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.3	-13	-176.6	-61.7	-34.5	0	0	0	112.2	D178	D178-D180 PolarHBondContact O-N 2.82Å; D178-D180 WeakPolarHBondContact OD1-CB 3.03Å; D178-D180 PolarHBondContact OD1-N 3.03Å
181	N	82.9	Confident	81.5	Confident	44 Å²	44	77.2 Å²	77.2	24%	0.235	42%	0.415	C	S	.	.			trans	-101.5	88.8	173.4	-171.8	-16.6	0	0	0	110.7	D178 T183 D184 P185 H187	D178-N181 HydrophobicContact CB-CB 4.37Å; D178-N181 PolarHBondContact O-N 3.38Å; N181-T183 PolarHBondContact O-N 3.47Å; N181-T183 PolarHBondContact OD1-N 3Å; N181-T183 PolarHBondContact OD1-OG1 3.24Å; N181-D184 PolarHBondContact ND2-O 2.77Å; N181-D184 CarbonylContact O-C 3.56Å; N181-D184 PolarHBondContact OD1-N 2.96Å; N181-P185 WeakPolarHBondContact O-CD 3.41Å; N181-P185 WeakPolarHBondContact O-CG 3.46Å; N181-H187 PolarHBondContact ND2-ND1 2.76Å
182	E	81.5	Confident	81.9	Confident	187 Å²	187	77.2 Å²	77.2	87%	0.874	41%	0.409	S	S	*	.	S	Bend	trans	-63	-22.8	-177.4	-62.4	-173.9	172.3	0	0	114
183	T	84.8	Confident	82	Confident	134 Å²	134	77.8 Å²	77.8	82%	0.822	40%	0.396	S	S	*	.	S	Bend	trans	-89.5	-36	-176.5	51.1	0	0	0	0	113.9	N181	N181-T183 PolarHBondContact O-N 3.47Å; N181-T183 PolarHBondContact OD1-N 3Å; N181-T183 PolarHBondContact OD1-OG1 3.24Å
184	D	82.9	Confident	81.6	Confident	54 Å²	54	81.8 Å²	81.8	29%	0.289	42%	0.418	S	S	.	.			trans	-145.5	85	174.2	-173.9	5.9	0	0	0	110.9	N181 F186 H187	N181-D184 PolarHBondContact ND2-O 2.77Å; N181-D184 CarbonylContact O-C 3.56Å; N181-D184 PolarHBondContact OD1-N 2.96Å; D184-F186 PolarHBondContact O-N 2.93Å; D184-F186 VanDerWaalsContact O-N 3.12Å; D184-F186 PolarHBondContact OD1-N 3.44Å; D184-F186 VanDerWaalsContact OD1-N 3.13Å; D184-H187 HydrophobicContact CB-CB 4.2Å; D184-H187 PolarHBondContact O-N 2.69Å; D184-H187 PolarHBondContact O-ND1 3.13Å; D184-H187 PolarHBondContact OD1-N 2.87Å; D184-H187 VanDerWaalsContact OD2-CA 3.3Å; D184-H187 WeakPolarHBondContact OD2-CA 3.05Å; D184-H187 WeakPolarHBondContact OD2-CB 3.43Å
185	P	86.1	Confident	81.1	Confident	30 Å²	30	81.9 Å²	81.9	20%	0.195	43%	0.425	C	S	.	.	T	Hydrogen-bonded Turn	trans	-63.6	-15.2	178.4	-23.1	33.2	0	0	0	114.2	Y177 D178 N181	Y177-P185 CarbonylContact C-O 3.31Å; Y177-P185 WeakPolarHBondContact CA-O 3.37Å; Y177-P185 HydrophobicContact CD2-CB 3.58Å; Y177-P185 HydrophobicContact CE2-CB 3.27Å; Y177-P185 HydrophobicContact CE2-CG 3.98Å; Y177-P185 HydrophobicContact CG-CB 4.46Å; D178-P185 PolarHBondContact N-O 3.26Å; D178-P185 WeakPolarHBondContact O-CA 3.47Å; N181-P185 WeakPolarHBondContact O-CD 3.41Å; N181-P185 WeakPolarHBondContact O-CG 3.46Å
186	F	85.7	Confident	80.9	Confident	90 Å²	90	80.3 Å²	80.3	40%	0.395	42%	0.415	S	S	.	.	T	Hydrogen-bonded Turn	trans	-112.8	16.6	-177.2	-70.4	-77.4	0	0	0	113	I176 Y177 D184 N188 V189 W190	I176-F186 HydrophobicContact CG2-CE1 4.5Å; I176-F186 WeakPolarHBondContact O-CD1 3.47Å; Y177-F186 HydrophobicContact CD2-CD2 4.35Å; Y177-F186 HydrophobicContact CD2-CE1 4.03Å; Y177-F186 AromaticContact CD2-CE2 3.76Å; Y177-F186 HydrophobicContact CD2-CE2 3.76Å; Y177-F186 AromaticContact CD2-CZ 3.59Å; Y177-F186 HydrophobicContact CD2-CZ 3.59Å; Y177-F186 HydrophobicContact CE2-CE2 4.16Å; Y177-F186 HydrophobicContact CE2-CZ 4.35Å; Y177-F186 HydrophobicContact CG-CZ 4.49Å; D184-F186 PolarHBondContact O-N 2.93Å; D184-F186 VanDerWaalsContact O-N 3.12Å; D184-F186 PolarHBondContact OD1-N 3.44Å; D184-F186 VanDerWaalsContact OD1-N 3.13Å; F186-N188 VanDerWaalsContact C-N 3.26Å; F186-N188 PolarHBondContact O-N 3.35Å; F186-N188 VanDerWaalsContact O-N 3.16Å; F186-V189 HydrophobicContact CD1-CG2 4.44Å; F186-V189 WeakPolarHBondContact O-CA 3.29Å; F186-V189 WeakPolarHBondContact O-CB 3.22Å; F186-V189 PolarHBondContact O-N 3.27Å; F186-W190 PolarHBondContact O-N 3.16Å; F186-W190 VanDerWaalsContact O-N 3.1Å
187	H	83.3	Confident	80.9	Confident	35 Å²	35	78.3 Å²	78.3	16%	0.162	41%	0.406	C	S	.	.	H	α-helix	trans	-49.7	-43.6	-177.6	61.5	-81.9	0	0	0	113.2	D178 N181 D184 V189 W190 D191	D178-H187 IonicContact OD2-CE1 3.44Å; D178-H187 PolarHBondContact OD2-CE1 3.44Å; D178-H187 VanDerWaalsContact OD2-CE1 3.27Å; D178-H187 IonicContact OD2-NE2 3.71Å; N181-H187 PolarHBondContact ND2-ND1 2.76Å; D184-H187 HydrophobicContact CB-CB 4.2Å; D184-H187 PolarHBondContact O-N 2.69Å; D184-H187 PolarHBondContact O-ND1 3.13Å; D184-H187 PolarHBondContact OD1-N 2.87Å; D184-H187 VanDerWaalsContact OD2-CA 3.3Å; D184-H187 WeakPolarHBondContact OD2-CA 3.05Å; D184-H187 WeakPolarHBondContact OD2-CB 3.43Å; H187-V189 PolarHBondContact O-N 2.92Å; H187-V189 VanDerWaalsContact O-N 3.14Å; H187-W190 PolarHBondContact O-N 3.24Å; H187-D191 WeakPolarHBondContact O-CB 3.37Å; H187-D191 VanDerWaalsContact O-CG 3.29Å; H187-D191 PolarHBondContact O-N 2.83Å
188	N	80.8	Confident	80.9	Confident	31 Å²	31	75.6 Å²	75.6	17%	0.166	40%	0.404	C	S	.	.	H	α-helix	trans	-59.4	-27.7	177.9	-63.9	-44	0	0	0	113.7	N173 L175 F186 K192 W243	N173-N188 PolarHBondContact O-ND2 2.68Å; N173-N188 VanDerWaalsContact O-ND2 3.1Å; L175-N188 PolarHBondContact O-ND2 3.11Å; F186-N188 VanDerWaalsContact C-N 3.26Å; F186-N188 PolarHBondContact O-N 3.35Å; F186-N188 VanDerWaalsContact O-N 3.16Å; N188-K192 VanDerWaalsContact O-CG 3.3Å; N188-K192 WeakPolarHBondContact O-CG 3.5Å; N188-W243 HydrophobicContact CB-CZ2 4.44Å
189	V	82.9	Confident	81	Confident	32 Å²	32	77.9 Å²	77.9	19%	0.194	43%	0.425	C	S	.	.	H	α-helix	trans	-84.1	-45.5	177.1	-178.4	0	0	0	0	110.3	I176 F186 H187 D191 K192 L193 W243	I176-V189 HydrophobicContact CG2-CG2 4.04Å; F186-V189 HydrophobicContact CD1-CG2 4.44Å; F186-V189 WeakPolarHBondContact O-CA 3.29Å; F186-V189 WeakPolarHBondContact O-CB 3.22Å; F186-V189 PolarHBondContact O-N 3.27Å; H187-V189 PolarHBondContact O-N 2.92Å; H187-V189 VanDerWaalsContact O-N 3.14Å; V189-D191 PolarHBondContact O-N 3.49Å; V189-K192 PolarHBondContact O-N 2.72Å; V189-K192 VanDerWaalsContact O-N 3.16Å; V189-L193 HydrophobicContact CG1-CD1 4.15Å; V189-L193 HydrophobicContact CG1-CG 4.49Å; V189-L193 WeakPolarHBondContact O-CG 3.19Å; V189-L193 PolarHBondContact O-N 3.46Å; V189-W243 HydrophobicContact CG2-CH2 3.99Å; V189-W243 HydrophobicContact CG2-CZ2 4.4Å
190	W	82.9	Confident	81.4	Confident	153 Å²	153	76.1 Å²	76.1	58%	0.58	41%	0.41	S	S	*	.	H	α-helix	trans	-63.4	-40.4	-178.5	-66.8	123.4	0	0	0	112.7	F186 H187 K192 L193	F186-W190 PolarHBondContact O-N 3.16Å; F186-W190 VanDerWaalsContact O-N 3.1Å; H187-W190 PolarHBondContact O-N 3.24Å; W190-K192 PolarHBondContact O-N 2.96Å; W190-K192 VanDerWaalsContact O-N 3.12Å; W190-L193 HydrophobicContact CE3-CD1 3.58Å; W190-L193 HydrophobicContact CZ3-CD1 3.61Å; W190-L193 PolarHBondContact O-N 2.94Å
191	D	76.3	Confident	81.9	Confident	122 Å²	122	72.5 Å²	72.5	65%	0.652	39%	0.388	S	S	*	.	H	α-helix	trans	-59	-26.3	177.3	-73.5	-15.2	0	0	0	112.5	H187 V189	H187-D191 WeakPolarHBondContact O-CB 3.37Å; H187-D191 VanDerWaalsContact O-CG 3.29Å; H187-D191 PolarHBondContact O-N 2.83Å; V189-D191 PolarHBondContact O-N 3.49Å
192	K	71.9	Confident	82.4	Confident	25 Å²	25	74.9 Å²	74.9	11%	0.109	40%	0.4	C	S	.	.	H	α-helix	trans	-89.3	-22.1	178.4	-61.4	-73.7	-179.6	154.6	0	113.2	N188 V189 W190 F196 D244 M248	N188-K192 VanDerWaalsContact O-CG 3.3Å; N188-K192 WeakPolarHBondContact O-CG 3.5Å; V189-K192 PolarHBondContact O-N 2.72Å; V189-K192 VanDerWaalsContact O-N 3.16Å; W190-K192 PolarHBondContact O-N 2.96Å; W190-K192 VanDerWaalsContact O-N 3.12Å; K192-F196 WeakPolarHBondContact O-CB 3.46Å; K192-D244 WeakPolarHBondContact CD-OD2 3.32Å; K192-D244 WeakPolarHBondContact CE-OD2 3.42Å; K192-D244 IonicContact NZ-OD2 3.95Å; K192-D244 PolarHBondContact NZ-OD2 2.98Å; K192-M248 HydrophobicContact CB-CE 3.38Å; K192-M248 HydrophobicContact CB-SD 4.31Å; K192-M248 HydrophobicContact CD-CE 4.34Å; K192-M248 HydrophobicContact CG-CE 3.81Å
193	L	76.6	Confident	83	Confident	74 Å²	74	67 Å²	67	39%	0.387	37%	0.369	S	S	.	.	H	α-helix	trans	-78.1	-20.6	-177.7	-72.5	176.4	0	0	0	113.9	V189 W190 G195 V197	V189-L193 HydrophobicContact CG1-CD1 4.15Å; V189-L193 HydrophobicContact CG1-CG 4.49Å; V189-L193 WeakPolarHBondContact O-CG 3.19Å; V189-L193 PolarHBondContact O-N 3.46Å; W190-L193 HydrophobicContact CE3-CD1 3.58Å; W190-L193 HydrophobicContact CZ3-CD1 3.61Å; W190-L193 PolarHBondContact O-N 2.94Å; L193-G195 PolarHBondContact O-N 2.84Å; L193-V197 HydrophobicContact CD2-CB 4.42Å; L193-V197 HydrophobicContact CD2-CG2 3.65Å
194	D	66.1	Low	83.6	Confident	153 Å²	153	60.8 Å²	60.8	82%	0.818	33%	0.33	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.1	-21.3	-168.7	-160.1	21.1	0	0	0	114.6
195	G	72.7	Confident	84.2	Confident	40 Å²	40	61 Å²	61	41%	0.412	33%	0.328	S	S	.	.	T	Hydrogen-bonded Turn	trans	-159.9	-23.6	178.9	0	0	0	0	0	116.3	L193 P198 A199	L193-G195 PolarHBondContact O-N 2.84Å; G195-P198 WeakPolarHBondContact O-CD 3.44Å; G195-P198 WeakPolarHBondContact O-CG 3.4Å; G195-A199 VanDerWaalsContact O-CB 3.26Å; G195-A199 WeakPolarHBondContact O-CB 3.36Å; G195-A199 PolarHBondContact O-N 2.87Å
196	F	78.3	Confident	84.7	Confident	45 Å²	45	62.4 Å²	62.4	20%	0.197	33%	0.333	C	S	.	.	H	α-helix	trans	-72.6	-48.2	-176.5	179.1	-93.2	0	0	0	112	K192 A199 H200 E240 D244 M248 D249	K192-F196 WeakPolarHBondContact O-CB 3.46Å; F196-A199 PolarHBondContact O-N 3.22Å; F196-H200 AromaticContact CD1-ND1 3.63Å; F196-H200 AromaticContact CD2-CE1 3.58Å; F196-H200 AromaticContact CD2-ND1 3.63Å; F196-H200 AromaticContact CE1-CE1 3.84Å; F196-H200 AromaticContact CE1-ND1 3.56Å; F196-H200 AromaticContact CE2-CE1 3.16Å; F196-H200 WeakPolarHBondContact CE2-CE1 3.47Å; F196-H200 AromaticContact CE2-ND1 3.57Å; F196-H200 AromaticContact CG-ND1 3.67Å; F196-H200 AromaticContact CZ-CE1 3.29Å; F196-H200 WeakPolarHBondContact CZ-CE1 3.39Å; F196-H200 AromaticContact CZ-ND1 3.51Å; F196-H200 PolarHBondContact O-N 3.15Å; F196-H200 PolarHBondContact O-ND1 3.18Å; F196-E240 WeakPolarHBondContact CZ-OE2 3.27Å; F196-D244 WeakPolarHBondContact CE1-OD1 3.43Å; F196-M248 HydrophobicContact CD1-CE 4.49Å; F196-M248 HydrophobicContact CE1-CE 4.43Å; F196-D249 WeakPolarHBondContact CE1-OD1 3.35Å; F196-D249 WeakPolarHBondContact CE1-OD2 3.46Å; F196-D249 WeakPolarHBondContact CZ-OD1 3.38Å; F196-D249 VanDerWaalsContact CZ-OD2 3.23Å; F196-D249 WeakPolarHBondContact CZ-OD2 3.27Å
197	V	83.6	Confident	85.1	Confident	33 Å²	33	60.2 Å²	60.2	20%	0.2	32%	0.323	C	S	.	.	H	α-helix	trans	-55.3	-53.5	175.4	171.6	0	0	0	0	113.5	L193 A199 H200 F201 M248	L193-V197 HydrophobicContact CD2-CB 4.42Å; L193-V197 HydrophobicContact CD2-CG2 3.65Å; V197-A199 VanDerWaalsContact C-N 3.28Å; V197-A199 PolarHBondContact O-N 3.46Å; V197-H200 PolarHBondContact O-N 3.48Å; V197-F201 WeakPolarHBondContact O-CB 3.34Å; V197-F201 PolarHBondContact O-N 3.22Å; V197-M248 HydrophobicContact CG2-CG 4.18Å; V197-M248 HydrophobicContact CG2-SD 3.84Å
198	P	87.3	Confident	85.7	Confident	70 Å²	70	58.5 Å²	58.5	46%	0.455	32%	0.315	S	S	.	.	H	α-helix	trans	-64.7	-32.5	179.2	22.9	-32.1	0	0	0	112.6	G195 L202	G195-P198 WeakPolarHBondContact O-CD 3.44Å; G195-P198 WeakPolarHBondContact O-CG 3.4Å; P198-L202 WeakPolarHBondContact O-CB 3.27Å; P198-L202 PolarHBondContact O-N 3.08Å
199	A	87.8	Confident	86.3	Confident	61 Å²	61	59.1 Å²	59.1	50%	0.504	32%	0.318	S	S	.	.	H	α-helix	trans	-67.2	-46.9	176.1	0	0	0	0	0	112.2	G195 F196 V197 G203	G195-A199 VanDerWaalsContact O-CB 3.26Å; G195-A199 WeakPolarHBondContact O-CB 3.36Å; G195-A199 PolarHBondContact O-N 2.87Å; F196-A199 PolarHBondContact O-N 3.22Å; V197-A199 VanDerWaalsContact C-N 3.28Å; V197-A199 PolarHBondContact O-N 3.46Å; A199-G203 WeakPolarHBondContact O-CA 3.33Å; A199-G203 PolarHBondContact O-N 3.16Å
200	H	91.1	Very high	86.7	Confident	40 Å²	40	58.5 Å²	58.5	19%	0.185	31%	0.314	C	S	.	.	H	α-helix	trans	-63.6	-49.8	176.6	-83.5	94.7	0	0	0	111.6	F196 V197 L202 G203 W204 D249 C253	F196-H200 AromaticContact CD1-ND1 3.63Å; F196-H200 AromaticContact CD2-CE1 3.58Å; F196-H200 AromaticContact CD2-ND1 3.63Å; F196-H200 AromaticContact CE1-CE1 3.84Å; F196-H200 AromaticContact CE1-ND1 3.56Å; F196-H200 AromaticContact CE2-CE1 3.16Å; F196-H200 WeakPolarHBondContact CE2-CE1 3.47Å; F196-H200 AromaticContact CE2-ND1 3.57Å; F196-H200 AromaticContact CG-ND1 3.67Å; F196-H200 AromaticContact CZ-CE1 3.29Å; F196-H200 WeakPolarHBondContact CZ-CE1 3.39Å; F196-H200 AromaticContact CZ-ND1 3.51Å; F196-H200 PolarHBondContact O-N 3.15Å; F196-H200 PolarHBondContact O-ND1 3.18Å; V197-H200 PolarHBondContact O-N 3.48Å; H200-L202 PolarHBondContact O-N 2.96Å; H200-G203 PolarHBondContact O-N 3.15Å; H200-W204 VanDerWaalsContact O-CD1 3.26Å; H200-W204 PolarHBondContact O-N 2.73Å; H200-D249 IonicContact CD2-OD1 2.88Å; H200-D249 IonicContact CG-OD1 2.77Å; H200-D249 IonicContact ND1-OD1 3.71Å; H200-C253 HydrophobicContact CB-CB 3.51Å
201	F	94.7	Very high	87.2	Confident	70 Å²	70	51.3 Å²	51.3	31%	0.307	29%	0.286	S	S	.	.	H	α-helix	trans	-57.5	-51.8	178.1	174.4	-93.6	0	0	0	112.2	V197 G203 W204 Y205 L256 C260	V197-F201 WeakPolarHBondContact O-CB 3.34Å; V197-F201 PolarHBondContact O-N 3.22Å; F201-G203 VanDerWaalsContact C-N 3.34Å; F201-G203 PolarHBondContact O-N 2.96Å; F201-W204 PolarHBondContact O-N 3.38Å; F201-Y205 WeakPolarHBondContact O-CB 3.3Å; F201-Y205 PolarHBondContact O-N 3.4Å; F201-L256 HydrophobicContact CD2-CB 4.01Å; F201-L256 HydrophobicContact CE2-CB 3.89Å; F201-C260 HydrophobicContact CE2-CB 4.46Å; F201-C260 HydrophobicContact CZ-CB 4.16Å
202	L	94	Very high	88	Confident	93 Å²	93	47 Å²	47	49%	0.487	26%	0.261	S	S	.	.	H	α-helix	trans	-67.5	-37.9	-179.1	-176.6	62.4	0	0	0	111.4	P198 H200 Y205 L206	P198-L202 WeakPolarHBondContact O-CB 3.27Å; P198-L202 PolarHBondContact O-N 3.08Å; H200-L202 PolarHBondContact O-N 2.96Å; L202-Y205 HydrophobicContact CD1-CD1 4.14Å; L202-Y205 PolarHBondContact O-N 2.89Å; L202-L206 HydrophobicContact CD1-CG 4.41Å; L202-L206 HydrophobicContact CG-CD1 4.27Å; L202-L206 WeakPolarHBondContact O-CG 3.49Å; L202-L206 PolarHBondContact O-N 2.77Å
203	G	93.7	Very high	89	Confident	22 Å²	22	47.5 Å²	47.5	23%	0.227	27%	0.265	C	S	.	.	H	α-helix	trans	-57.5	-52.2	175.1	0	0	0	0	0	111.3	A199 H200 F201 L206 K207	A199-G203 WeakPolarHBondContact O-CA 3.33Å; A199-G203 PolarHBondContact O-N 3.16Å; H200-G203 PolarHBondContact O-N 3.15Å; F201-G203 VanDerWaalsContact C-N 3.34Å; F201-G203 PolarHBondContact O-N 2.96Å; G203-L206 PolarHBondContact O-N 3.1Å; G203-K207 WeakPolarHBondContact O-CB 3.49Å; G203-K207 VanDerWaalsContact O-CG 3.22Å; G203-K207 WeakPolarHBondContact O-CG 3.45Å; G203-K207 PolarHBondContact O-N 2.91Å
204	W	96.2	Very high	89.8	Confident	3 Å²	3	48.5 Å²	48.5	1%	0.011	26%	0.264	C	S	.	.	H	α-helix	trans	-68.7	-34.4	179.2	-82.1	99.4	0	0	0	113.9	H200 F201 K207 T208 C217 I220 S221 N254 I258	H200-W204 VanDerWaalsContact O-CD1 3.26Å; H200-W204 PolarHBondContact O-N 2.73Å; F201-W204 PolarHBondContact O-N 3.38Å; W204-K207 HydrophobicContact CD2-CD 4.21Å; W204-K207 HydrophobicContact CE3-CB 4.41Å; W204-K207 HydrophobicContact CE3-CD 4.2Å; W204-K207 HydrophobicContact CH2-CD 4.45Å; W204-K207 HydrophobicContact CZ2-CD 4.49Å; W204-K207 HydrophobicContact CZ3-CD 4.34Å; W204-T208 VanDerWaalsContact O-CB 3.29Å; W204-T208 WeakPolarHBondContact O-CB 3.35Å; W204-T208 PolarHBondContact O-N 2.79Å; W204-T208 PolarHBondContact O-OG1 2.95Å; W204-C217 HydrophobicContact CZ3-CB 4.37Å; W204-C217 VanDerWaalsContact CZ3-O 3.3Å; W204-C217 WeakPolarHBondContact CZ3-O 3.49Å; W204-I220 HydrophobicContact CH2-CB 4.12Å; W204-I220 HydrophobicContact CH2-CG2 3.84Å; W204-S221 VanDerWaalsContact CZ2-CB 3.45Å; W204-N254 VanDerWaalsContact CD1-CB 3.48Å; W204-N254 HydrophobicContact CD2-CB 4.01Å; W204-N254 HydrophobicContact CG-CB 3.73Å; W204-N254 PolarHBondContact NE1-ND2 2.91Å; W204-N254 PolarHBondContact NE1-OD1 2.87Å; W204-I258 HydrophobicContact CB-CG1 4.28Å; W204-I258 HydrophobicContact CD2-CD1 4.3Å; W204-I258 HydrophobicContact CD2-CG1 4.32Å; W204-I258 HydrophobicContact CE3-CD1 3.68Å; W204-I258 HydrophobicContact CE3-CG1 3.68Å; W204-I258 HydrophobicContact CZ3-CD1 4.12Å; W204-I258 HydrophobicContact CZ3-CG1 4.48Å
205	Y	96.8	Very high	91.2	Very high	60 Å²	60	50 Å²	50	24%	0.235	26%	0.258	C	S	.	.	H	α-helix	trans	-55.7	-52.9	168.8	171.7	-99.7	0	0	0	111.2	F201 L202 T208 L209 G257 C260	F201-Y205 WeakPolarHBondContact O-CB 3.3Å; F201-Y205 PolarHBondContact O-N 3.4Å; L202-Y205 HydrophobicContact CD1-CD1 4.14Å; L202-Y205 PolarHBondContact O-N 2.89Å; Y205-T208 WeakPolarHBondContact O-CB 3.36Å; Y205-T208 PolarHBondContact O-N 3.06Å; Y205-L209 HydrophobicContact CD1-CD1 4.45Å; Y205-L209 HydrophobicContact CE1-CD1 3.78Å; Y205-L209 HydrophobicContact CE1-CG 4.43Å; Y205-L209 HydrophobicContact CE2-CD2 4.41Å; Y205-L209 WeakPolarHBondContact O-CG 3.12Å; Y205-L209 PolarHBondContact O-N 3.47Å; Y205-L209 VanDerWaalsContact O-N 3.16Å; Y205-G257 WeakPolarHBondContact CA-O 3.46Å; Y205-C260 HydrophobicContact CD2-CB 4.15Å
206	L	95.3	Very high	92.2	Very high	58 Å²	58	48.4 Å²	48.4	30%	0.304	24%	0.24	S	C	.	.	H	α-helix	trans	-66.1	-42.7	-179.5	-67.7	175.1	0	0	0	112.7	L202 G203 T208 L209 M210 V355	L202-L206 HydrophobicContact CD1-CG 4.41Å; L202-L206 HydrophobicContact CG-CD1 4.27Å; L202-L206 WeakPolarHBondContact O-CG 3.49Å; L202-L206 PolarHBondContact O-N 2.77Å; G203-L206 PolarHBondContact O-N 3.1Å; L206-T208 PolarHBondContact O-N 2.86Å; L206-L209 HydrophobicContact CD2-CD1 4.38Å; L206-L209 WeakPolarHBondContact O-CB 3.49Å; L206-L209 PolarHBondContact O-N 3Å; L206-L209 VanDerWaalsContact O-N 3.13Å; L206-M210 PolarHBondContact O-N 2.95Å; L206-V355 HydrophobicContact CB-CG1 4.46Å; L206-V355 HydrophobicContact CB-CG2 4.42Å; L206-V355 HydrophobicContact CD1-CG2 4.42Å
207	K	95.3	Very high	93	Very high	44 Å²	44	46.2 Å²	46.2	19%	0.191	23%	0.23	C	C	.	.	H	α-helix	trans	-58.8	-38.3	174.9	-69.9	171.2	-167.6	175.8	0	111.3	G203 W204 M210 I211 F324 E328	G203-K207 WeakPolarHBondContact O-CB 3.49Å; G203-K207 VanDerWaalsContact O-CG 3.22Å; G203-K207 WeakPolarHBondContact O-CG 3.45Å; G203-K207 PolarHBondContact O-N 2.91Å; W204-K207 HydrophobicContact CD2-CD 4.21Å; W204-K207 HydrophobicContact CE3-CB 4.41Å; W204-K207 HydrophobicContact CE3-CD 4.2Å; W204-K207 HydrophobicContact CH2-CD 4.45Å; W204-K207 HydrophobicContact CZ2-CD 4.49Å; W204-K207 HydrophobicContact CZ3-CD 4.34Å; K207-M210 WeakPolarHBondContact O-CB 3.43Å; K207-M210 PolarHBondContact O-N 3.38Å; K207-M210 VanDerWaalsContact O-N 3.15Å; K207-I211 HydrophobicContact CB-CD1 4.49Å; K207-I211 WeakPolarHBondContact O-CG1 3.47Å; K207-I211 PolarHBondContact O-N 3.37Å; K207-F324 HydrophobicContact CB-CZ 4.23Å; K207-F324 HydrophobicContact CD-CE1 4.15Å; K207-F324 HydrophobicContact CD-CZ 4.32Å; K207-F324 HydrophobicContact CG-CE1 4.32Å; K207-F324 HydrophobicContact CG-CZ 3.99Å; K207-E328 WeakPolarHBondContact CD-OE1 3.45Å; K207-E328 WeakPolarHBondContact CE-OE1 3.38Å; K207-E328 IonicContact NZ-OE1 3.07Å; K207-E328 PolarHBondContact NZ-OE1 3.4Å
208	T	95.9	Very high	93.6	Very high	0 Å²	0	46.5 Å²	46.5	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-65.9	-39.4	176.6	-58.5	0	0	0	0	111.8	W204 Y205 L206 M210 I211 R212 I258 M262 L265	W204-T208 VanDerWaalsContact O-CB 3.29Å; W204-T208 WeakPolarHBondContact O-CB 3.35Å; W204-T208 PolarHBondContact O-N 2.79Å; W204-T208 PolarHBondContact O-OG1 2.95Å; Y205-T208 WeakPolarHBondContact O-CB 3.36Å; Y205-T208 PolarHBondContact O-N 3.06Å; L206-T208 PolarHBondContact O-N 2.86Å; T208-M210 PolarHBondContact O-N 2.89Å; T208-I211 PolarHBondContact O-N 3.49Å; T208-R212 WeakPolarHBondContact O-CA 3.36Å; T208-R212 PolarHBondContact O-N 2.99Å; T208-I258 HydrophobicContact CG2-CG2 4.38Å; T208-I258 WeakPolarHBondContact OG1-CA 3.13Å; T208-M262 HydrophobicContact CG2-CG 3.99Å; T208-M262 HydrophobicContact CG2-SD 3.68Å; T208-L265 HydrophobicContact CG2-CD1 4.22Å
209	L	92.9	Very high	94	Very high	44 Å²	44	46.6 Å²	46.6	23%	0.23	23%	0.226	C	C	.	.	H	α-helix	trans	-61.8	-27.4	174.8	-57.5	-176.3	0	0	0	113.2	Y205 L206 R212 T264 L265	Y205-L209 HydrophobicContact CD1-CD1 4.45Å; Y205-L209 HydrophobicContact CE1-CD1 3.78Å; Y205-L209 HydrophobicContact CE1-CG 4.43Å; Y205-L209 HydrophobicContact CE2-CD2 4.41Å; Y205-L209 WeakPolarHBondContact O-CG 3.12Å; Y205-L209 PolarHBondContact O-N 3.47Å; Y205-L209 VanDerWaalsContact O-N 3.16Å; L206-L209 HydrophobicContact CD2-CD1 4.38Å; L206-L209 WeakPolarHBondContact O-CB 3.49Å; L206-L209 PolarHBondContact O-N 3Å; L206-L209 VanDerWaalsContact O-N 3.13Å; L209-R212 VanDerWaalsContact O-CG 3.27Å; L209-R212 WeakPolarHBondContact O-CG 3.45Å; L209-R212 PolarHBondContact O-NE 3.27Å; L209-T264 HydrophobicContact CD2-CG2 3.96Å; L209-L265 HydrophobicContact CB-CD2 4.46Å; L209-L265 HydrophobicContact CD2-CD2 3.66Å; L209-L265 HydrophobicContact CD2-CG 4.24Å
210	M	92.3	Very high	94.4	Very high	19 Å²	19	43.7 Å²	43.7	9%	0.094	20%	0.202	C	C	.	.	H	α-helix	trans	-82.4	-50.6	178	170.7	165.3	76.9	0	0	113	L206 K207 T208 F324 G358 G359 M362	L206-M210 PolarHBondContact O-N 2.95Å; K207-M210 WeakPolarHBondContact O-CB 3.43Å; K207-M210 PolarHBondContact O-N 3.38Å; K207-M210 VanDerWaalsContact O-N 3.15Å; T208-M210 PolarHBondContact O-N 2.89Å; M210-F324 HydrophobicContact CE-CD2 4.48Å; M210-F324 HydrophobicContact CE-CE2 3.25Å; M210-F324 HydrophobicContact CE-CZ 3.31Å; M210-G358 WeakPolarHBondContact SD-CA 3.29Å; M210-G359 PolarHBondContact SD-N 3.43Å; M210-G359 VanDerWaalsContact SD-N 3.4Å; M210-M362 HydrophobicContact CG-CG 3.98Å
211	I	92.8	Very high	94.7	Very high	1 Å²	1	41.8 Å²	41.8	1%	0.005	19%	0.193	C	C	.	.	H	α-helix	trans	-76.7	-37.8	-176.2	-64.1	160.5	0	0	0	111.9	K207 T208 D213 M216 I220 F303 F324 M362	K207-I211 HydrophobicContact CB-CD1 4.49Å; K207-I211 WeakPolarHBondContact O-CG1 3.47Å; K207-I211 PolarHBondContact O-N 3.37Å; T208-I211 PolarHBondContact O-N 3.49Å; I211-D213 VanDerWaalsContact C-N 3.27Å; I211-D213 HydrophobicContact CG2-CB 4.36Å; I211-D213 PolarHBondContact O-N 3.01Å; I211-M216 HydrophobicContact CG2-CB 3.72Å; I211-M216 HydrophobicContact CG2-CE 4.2Å; I211-M216 HydrophobicContact CG2-SD 4.42Å; I211-I220 HydrophobicContact CD1-CD1 3.73Å; I211-F303 WeakPolarHBondContact O-CD2 3.47Å; I211-F324 HydrophobicContact CD1-CD2 4.24Å; I211-F324 HydrophobicContact CD1-CE1 4.37Å; I211-F324 HydrophobicContact CD1-CE2 3.61Å; I211-F324 HydrophobicContact CD1-CZ 3.7Å; I211-F324 HydrophobicContact CG1-CD2 4.3Å; I211-F324 HydrophobicContact CG1-CE2 3.67Å; I211-F324 HydrophobicContact CG1-CZ 4.2Å; I211-M362 HydrophobicContact CG2-CE 4.48Å
212	R	92.7	Very high	94.7	Very high	31 Å²	31	41.2 Å²	41.2	12%	0.117	20%	0.195	C	C	.	.			trans	59.5	26.6	177.3	-47.1	-176.3	-176.5	173.1	1.1	116.2	T208 L209 L265 V301 F303	T208-R212 WeakPolarHBondContact O-CA 3.36Å; T208-R212 PolarHBondContact O-N 2.99Å; L209-R212 VanDerWaalsContact O-CG 3.27Å; L209-R212 WeakPolarHBondContact O-CG 3.45Å; L209-R212 PolarHBondContact O-NE 3.27Å; R212-L265 HydrophobicContact CB-CD1 3.87Å; R212-L265 HydrophobicContact CG-CD1 4.09Å; R212-L265 HydrophobicContact CG-CD2 4.26Å; R212-V301 PolarHBondContact NH1-O 2.86Å; R212-F303 HydrophobicContact CB-CD2 3.75Å; R212-F303 HydrophobicContact CB-CE2 4.2Å; R212-F303 HydrophobicContact CB-CG 4.29Å; R212-F303 HydrophobicContact CG-CD2 4.09Å; R212-F303 HydrophobicContact CG-CE2 4.02Å
213	D	93.4	Very high	94.8	Very high	37 Å²	37	39.7 Å²	39.7	20%	0.198	19%	0.186	C	C	.	.			trans	-141.4	125.3	177.5	-175.4	-85.2	0	0	0	110.7	I211 W215 M216 C217	I211-D213 VanDerWaalsContact C-N 3.27Å; I211-D213 HydrophobicContact CG2-CB 4.36Å; I211-D213 PolarHBondContact O-N 3.01Å; D213-W215 PolarHBondContact O-N 3.49Å; D213-W215 PolarHBondContact OD1-N 3.39Å; D213-M216 HydrophobicContact CB-CB 4.09Å; D213-M216 HydrophobicContact CB-CG 4.16Å; D213-M216 HydrophobicContact CB-SD 4.12Å; D213-M216 PolarHBondContact OD1-N 3.44Å; D213-C217 WeakPolarHBondContact O-CB 3.47Å; D213-C217 PolarHBondContact O-N 2.89Å; D213-C217 PolarHBondContact O-SG 3.27Å
214	W	94.1	Very high	94.8	Very high	95 Å²	95	39.1 Å²	39.1	36%	0.36	18%	0.178	S	C	.	.	H	α-helix	trans	-59.7	-47.6	-177.6	170	-92.6	0	0	0	112.1	C217 M218 I258 M262	W214-C217 PolarHBondContact O-N 3.44Å; W214-M218 HydrophobicContact CD2-CG 4.22Å; W214-M218 HydrophobicContact CH2-SD 4.26Å; W214-M218 HydrophobicContact CZ2-CG 4Å; W214-M218 HydrophobicContact CZ2-SD 4.11Å; W214-M218 WeakPolarHBondContact O-CG 3.37Å; W214-M218 PolarHBondContact O-N 3.24Å; W214-I258 HydrophobicContact CD2-CG2 4.35Å; W214-I258 HydrophobicContact CE3-CG2 3.49Å; W214-I258 VanDerWaalsContact CE3-CG2 3.49Å; W214-I258 HydrophobicContact CZ3-CB 4.31Å; W214-I258 HydrophobicContact CZ3-CG2 3.62Å; W214-M262 HydrophobicContact CB-CE 4.17Å; W214-M262 HydrophobicContact CB-CG 4.34Å; W214-M262 HydrophobicContact CB-SD 4.32Å; W214-M262 HydrophobicContact CE3-CG 3.82Å
215	W	94	Very high	94.7	Very high	183 Å²	183	39.1 Å²	39.1	69%	0.693	18%	0.178	S	C	*	.	H	α-helix	trans	-69.8	-43.6	-174.4	-75	109.6	0	0	0	111.4	D213 C217 M218 I219	D213-W215 PolarHBondContact O-N 3.49Å; D213-W215 PolarHBondContact OD1-N 3.39Å; W215-C217 VanDerWaalsContact C-N 3.33Å; W215-C217 PolarHBondContact O-N 3.09Å; W215-M218 PolarHBondContact O-N 3.06Å; W215-I219 WeakPolarHBondContact O-CB 3.45Å; W215-I219 WeakPolarHBondContact O-CD1 3.36Å; W215-I219 WeakPolarHBondContact O-CG1 3.24Å; W215-I219 PolarHBondContact O-N 3.45Å
216	M	93.9	Very high	94.5	Very high	7 Å²	7	39.1 Å²	39.1	3%	0.034	18%	0.179	C	C	.	.	H	α-helix	trans	-60.4	-43.7	174.8	-69	179.3	63.1	0	0	111.4	I211 D213 I219 I220 W305 V317 I320 M362	I211-M216 HydrophobicContact CG2-CB 3.72Å; I211-M216 HydrophobicContact CG2-CE 4.2Å; I211-M216 HydrophobicContact CG2-SD 4.42Å; D213-M216 HydrophobicContact CB-CB 4.09Å; D213-M216 HydrophobicContact CB-CG 4.16Å; D213-M216 HydrophobicContact CB-SD 4.12Å; D213-M216 PolarHBondContact OD1-N 3.44Å; M216-I219 PolarHBondContact O-N 3.28Å; M216-I220 WeakPolarHBondContact O-CB 3.11Å; M216-I220 WeakPolarHBondContact O-CD1 3.46Å; M216-I220 VanDerWaalsContact O-CG1 3.23Å; M216-I220 WeakPolarHBondContact O-CG1 3.42Å; M216-I220 PolarHBondContact O-N 2.92Å; M216-W305 HydrophobicContact SD-CB 4.4Å; M216-W305 VanDerWaalsContact SD-CD1 3.54Å; M216-W305 HydrophobicContact SD-CD2 3.78Å; M216-W305 HydrophobicContact SD-CE3 4.43Å; M216-W305 HydrophobicContact SD-CG 3.66Å; M216-V317 HydrophobicContact CE-CG1 4.25Å; M216-V317 HydrophobicContact CG-CG1 4.26Å; M216-V317 HydrophobicContact SD-CG1 4.17Å; M216-I320 HydrophobicContact CE-CB 4.36Å; M216-I320 HydrophobicContact CE-CG2 3.78Å; M216-M362 HydrophobicContact CE-CE 4.35Å
217	C	96.3	Very high	94.4	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-62.5	-46.7	177.9	-65.2	0	0	0	0	111.8	W204 D213 W214 W215 I219 I220 S221 I258	W204-C217 HydrophobicContact CZ3-CB 4.37Å; W204-C217 VanDerWaalsContact CZ3-O 3.3Å; W204-C217 WeakPolarHBondContact CZ3-O 3.49Å; D213-C217 WeakPolarHBondContact O-CB 3.47Å; D213-C217 PolarHBondContact O-N 2.89Å; D213-C217 PolarHBondContact O-SG 3.27Å; W214-C217 PolarHBondContact O-N 3.44Å; W215-C217 VanDerWaalsContact C-N 3.33Å; W215-C217 PolarHBondContact O-N 3.09Å; C217-I219 VanDerWaalsContact C-N 3.34Å; C217-I219 PolarHBondContact O-N 2.91Å; C217-I220 PolarHBondContact O-N 3.02Å; C217-S221 WeakPolarHBondContact O-CB 3.23Å; C217-S221 PolarHBondContact O-N 3.37Å; C217-I258 HydrophobicContact CB-CD1 3.87Å; C217-I258 HydrophobicContact CB-CG1 3.95Å; C217-I258 HydrophobicContact CB-CG2 3.9Å
218	M	95.9	Very high	94.3	Very high	38 Å²	38	35.9 Å²	35.9	19%	0.187	16%	0.164	C	C	.	.	H	α-helix	trans	-63	-40.2	177.9	-71.6	-56.6	-55.5	0	0	112.2	W214 W215 S221 V222 I258	W214-M218 HydrophobicContact CD2-CG 4.22Å; W214-M218 HydrophobicContact CH2-SD 4.26Å; W214-M218 HydrophobicContact CZ2-CG 4Å; W214-M218 HydrophobicContact CZ2-SD 4.11Å; W214-M218 WeakPolarHBondContact O-CG 3.37Å; W214-M218 PolarHBondContact O-N 3.24Å; W215-M218 PolarHBondContact O-N 3.06Å; M218-S221 PolarHBondContact O-N 2.91Å; M218-V222 WeakPolarHBondContact O-CG2 3.42Å; M218-V222 PolarHBondContact O-N 2.97Å; M218-I258 HydrophobicContact CG-CD1 4.43Å; M218-I258 HydrophobicContact SD-CD1 3.57Å; M218-I258 VanDerWaalsContact SD-CD1 3.57Å
219	I	95.4	Very high	94	Very high	72 Å²	72	38.2 Å²	38.2	37%	0.369	17%	0.173	S	C	.	.	H	α-helix	trans	-63.4	-49.3	176.7	-70.1	164	0	0	0	110.2	W215 M216 C217 S221 V222 M223 I321	W215-I219 WeakPolarHBondContact O-CB 3.45Å; W215-I219 WeakPolarHBondContact O-CD1 3.36Å; W215-I219 WeakPolarHBondContact O-CG1 3.24Å; W215-I219 PolarHBondContact O-N 3.45Å; M216-I219 PolarHBondContact O-N 3.28Å; C217-I219 VanDerWaalsContact C-N 3.34Å; C217-I219 PolarHBondContact O-N 2.91Å; I219-S221 VanDerWaalsContact C-N 3.27Å; I219-S221 PolarHBondContact O-N 3.46Å; I219-V222 PolarHBondContact O-N 3Å; I219-M223 HydrophobicContact CG2-CG 4.11Å; I219-M223 HydrophobicContact CG2-SD 3.59Å; I219-M223 VanDerWaalsContact CG2-SD 3.59Å; I219-M223 WeakPolarHBondContact O-CB 3.27Å; I219-M223 WeakPolarHBondContact O-CG 3.39Å; I219-M223 PolarHBondContact O-N 3.49Å; I219-I321 HydrophobicContact CG2-CD1 4.03Å
220	I	96.3	Very high	93.9	Very high	0 Å²	0	36.2 Å²	36.2	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-60.8	-41.5	178.4	-65.4	164.1	0	0	0	109.7	W204 I211 M216 C217 M223 F224 I321 F324 L325	W204-I220 HydrophobicContact CH2-CB 4.12Å; W204-I220 HydrophobicContact CH2-CG2 3.84Å; I211-I220 HydrophobicContact CD1-CD1 3.73Å; M216-I220 WeakPolarHBondContact O-CB 3.11Å; M216-I220 WeakPolarHBondContact O-CD1 3.46Å; M216-I220 VanDerWaalsContact O-CG1 3.23Å; M216-I220 WeakPolarHBondContact O-CG1 3.42Å; M216-I220 PolarHBondContact O-N 2.92Å; C217-I220 PolarHBondContact O-N 3.02Å; I220-M223 PolarHBondContact O-N 3.28Å; I220-F224 VanDerWaalsContact O-CB 3.31Å; I220-F224 WeakPolarHBondContact O-CB 3.29Å; I220-F224 PolarHBondContact O-N 3.28Å; I220-I321 HydrophobicContact CD1-CG1 4.31Å; I220-I321 HydrophobicContact CG1-CB 4.41Å; I220-I321 HydrophobicContact CG1-CG1 4.07Å; I220-I321 HydrophobicContact CG1-CG2 4.07Å; I220-F324 HydrophobicContact CD1-CB 4.2Å; I220-F324 HydrophobicContact CD1-CD1 4.31Å; I220-F324 HydrophobicContact CD1-CD2 4.41Å; I220-F324 HydrophobicContact CD1-CG 4.07Å; I220-F324 HydrophobicContact CG2-CD1 3.75Å; I220-F324 HydrophobicContact CG2-CE1 4.2Å; I220-F324 HydrophobicContact CG2-CG 4.46Å; I220-L325 HydrophobicContact CG2-CD2 3.8Å; I220-L325 HydrophobicContact CG2-CG 4.44Å
221	S	96.2	Very high	94	Very high	0 Å²	0	36.1 Å²	36.1	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-60.3	-54.1	179.5	-179.4	0	0	0	0	112	W204 C217 M218 I219 M223 F224 E225 N254	W204-S221 VanDerWaalsContact CZ2-CB 3.45Å; C217-S221 WeakPolarHBondContact O-CB 3.23Å; C217-S221 PolarHBondContact O-N 3.37Å; M218-S221 PolarHBondContact O-N 2.91Å; I219-S221 VanDerWaalsContact C-N 3.27Å; I219-S221 PolarHBondContact O-N 3.46Å; S221-M223 VanDerWaalsContact C-N 3.34Å; S221-M223 PolarHBondContact O-N 3.31Å; S221-F224 PolarHBondContact O-N 2.98Å; S221-E225 PolarHBondContact O-N 3.27Å; S221-N254 VanDerWaalsContact OG-CB 3.23Å; S221-N254 WeakPolarHBondContact OG-CB 3.44Å; S221-N254 PolarHBondContact OG-ND2 3.29Å
222	V	95.4	Very high	93.9	Very high	58 Å²	58	38.9 Å²	38.9	35%	0.352	18%	0.175	S	C	.	.	H	α-helix	trans	-64.4	-39.5	179	170.6	0	0	0	0	111.8	M218 I219 F224 F226 W246 V250	M218-V222 WeakPolarHBondContact O-CG2 3.42Å; M218-V222 PolarHBondContact O-N 2.97Å; I219-V222 PolarHBondContact O-N 3Å; V222-F224 VanDerWaalsContact C-N 3.31Å; V222-F224 PolarHBondContact O-N 2.87Å; V222-F226 PolarHBondContact O-N 3.1Å; V222-F226 VanDerWaalsContact O-N 3.12Å; V222-W246 HydrophobicContact CG1-CZ3 4.23Å; V222-V250 HydrophobicContact CG2-CG1 3.82Å; V222-V250 HydrophobicContact CG2-CG2 4.45Å
223	M	95.2	Very high	93.7	Very high	62 Å²	62	40.2 Å²	40.2	31%	0.305	18%	0.183	S	C	.	.	H	α-helix	trans	-67.1	-33	178.5	-75.7	-174.4	73.4	0	0	112.3	I219 I220 S221 F226 L227 I321 L325	I219-M223 HydrophobicContact CG2-CG 4.11Å; I219-M223 HydrophobicContact CG2-SD 3.59Å; I219-M223 VanDerWaalsContact CG2-SD 3.59Å; I219-M223 WeakPolarHBondContact O-CB 3.27Å; I219-M223 WeakPolarHBondContact O-CG 3.39Å; I219-M223 PolarHBondContact O-N 3.49Å; I220-M223 PolarHBondContact O-N 3.28Å; S221-M223 VanDerWaalsContact C-N 3.34Å; S221-M223 PolarHBondContact O-N 3.31Å; M223-F226 PolarHBondContact O-N 2.99Å; M223-L227 WeakPolarHBondContact O-CG 3.38Å; M223-L227 PolarHBondContact O-N 3.38Å; M223-I321 HydrophobicContact CE-CG2 4.5Å; M223-I321 HydrophobicContact SD-CG2 3.86Å; M223-L325 HydrophobicContact CB-CD1 3.83Å; M223-L325 HydrophobicContact CB-CD2 4.08Å; M223-L325 HydrophobicContact CE-CD1 3.57Å; M223-L325 HydrophobicContact SD-CD1 3.99Å
224	F	95.3	Very high	93.6	Very high	10 Å²	10	39.4 Å²	39.4	4%	0.044	18%	0.178	C	C	.	.	H	α-helix	trans	-69	-46.4	178.1	-167.2	-99	0	0	0	111.3	I220 S221 V222 F226 L227 E228 L325 E328 F332	I220-F224 VanDerWaalsContact O-CB 3.31Å; I220-F224 WeakPolarHBondContact O-CB 3.29Å; I220-F224 PolarHBondContact O-N 3.28Å; S221-F224 PolarHBondContact O-N 2.98Å; V222-F224 VanDerWaalsContact C-N 3.31Å; V222-F224 PolarHBondContact O-N 2.87Å; F224-F226 PolarHBondContact O-N 3.24Å; F224-L227 WeakPolarHBondContact O-CA 3.45Å; F224-L227 VanDerWaalsContact O-CB 3.32Å; F224-L227 WeakPolarHBondContact O-CB 3.38Å; F224-L227 PolarHBondContact O-N 3.49Å; F224-E228 HydrophobicContact CD1-CG 4.29Å; F224-E228 HydrophobicContact CE1-CG 3.91Å; F224-E228 WeakPolarHBondContact CE1-OE1 3.26Å; F224-E228 HydrophobicContact CZ-CG 4.33Å; F224-E228 PolarHBondContact O-N 3.06Å; F224-L325 HydrophobicContact CB-CD2 4Å; F224-L325 HydrophobicContact CD2-CD2 4.2Å; F224-E328 HydrophobicContact CD2-CB 3.84Å; F224-E328 WeakPolarHBondContact CD2-OE2 3.16Å; F224-E328 HydrophobicContact CE2-CB 3.46Å; F224-E328 VanDerWaalsContact CE2-CB 3.46Å; F224-E328 HydrophobicContact CZ-CB 4.21Å; F224-F332 HydrophobicContact CE1-CE2 4.05Å; F224-F332 HydrophobicContact CE1-CZ 4.39Å; F224-F332 HydrophobicContact CE2-CE2 4.48Å; F224-F332 AromaticContact CZ-CD2 3.99Å; F224-F332 HydrophobicContact CZ-CD2 3.99Å; F224-F332 AromaticContact CZ-CE2 3.45Å; F224-F332 HydrophobicContact CZ-CE2 3.45Å; F224-F332 VanDerWaalsContact CZ-CE2 3.45Å; F224-F332 HydrophobicContact CZ-CZ 4.19Å
225	E	93.3	Very high	93.4	Very high	2 Å²	2	34.9 Å²	34.9	1%	0.009	16%	0.161	C	C	.	.	H	α-helix	trans	-57.3	-40.5	172.5	-59.1	-51.7	143.2	0	0	112.1	S221 L227 E228 Y229 H245 D249 V250 N254	S221-E225 PolarHBondContact O-N 3.27Å; E225-L227 VanDerWaalsContact C-N 3.29Å; E225-L227 PolarHBondContact O-N 3.5Å; E225-E228 PolarHBondContact O-N 3.46Å; E225-Y229 WeakPolarHBondContact O-CD2 3.42Å; E225-Y229 PolarHBondContact O-N 3.24Å; E225-Y229 VanDerWaalsContact O-N 3.08Å; E225-H245 IonicContact OE2-CE1 3.89Å; E225-H245 IonicContact OE2-CG 3.4Å; E225-H245 IonicContact OE2-ND1 2.66Å; E225-H245 PolarHBondContact OE2-ND1 3.45Å; E225-D249 WeakPolarHBondContact OE1-CB 3.34Å; E225-V250 HydrophobicContact CB-CG2 4.29Å; E225-V250 HydrophobicContact CG-CG2 3.44Å; E225-V250 VanDerWaalsContact CG-CG2 3.44Å; E225-N254 PolarHBondContact OE1-ND2 3.39Å
226	F	92.4	Very high	93	Very high	61 Å²	61	27.2 Å²	27.2	27%	0.268	13%	0.134	S	C	.	.	H	α-helix	trans	-65.8	-32.7	176.1	-171.6	-109.8	0	0	0	112.5	V222 M223 F224 S230 C415 W416	V222-F226 PolarHBondContact O-N 3.1Å; V222-F226 VanDerWaalsContact O-N 3.12Å; M223-F226 PolarHBondContact O-N 2.99Å; F224-F226 PolarHBondContact O-N 3.24Å; F226-S230 VanDerWaalsContact O-CB 3.26Å; F226-S230 WeakPolarHBondContact O-CB 3.31Å; F226-S230 PolarHBondContact O-N 3.39Å; F226-S230 PolarHBondContact O-OG 2.99Å; F226-C415 HydrophobicContact CE2-CB 4.28Å; F226-C415 HydrophobicContact CZ-CB 3.66Å; F226-W416 HydrophobicContact CD1-CD2 4.41Å; F226-W416 AromaticContact CD1-CE2 3.68Å; F226-W416 AromaticContact CD1-CH2 3.88Å; F226-W416 HydrophobicContact CD1-CH2 3.88Å; F226-W416 AromaticContact CD1-CZ2 3.37Å; F226-W416 HydrophobicContact CD1-CZ2 3.37Å; F226-W416 AromaticContact CE1-CD1 3.85Å; F226-W416 AromaticContact CE1-CD2 3.73Å; F226-W416 HydrophobicContact CE1-CD2 3.73Å; F226-W416 AromaticContact CE1-CE2 3.26Å; F226-W416 HydrophobicContact CE1-CE3 4.34Å; F226-W416 HydrophobicContact CE1-CG 4.09Å; F226-W416 HydrophobicContact CE1-CH2 4.17Å; F226-W416 AromaticContact CE1-CZ2 3.52Å; F226-W416 HydrophobicContact CE1-CZ2 3.52Å; F226-W416 AromaticContact CE1-NE1 3.34Å; F226-W416 VanDerWaalsContact CE1-NE1 3.34Å
227	L	94.3	Very high	92.5	Very high	26 Å²	26	28.3 Å²	28.3	14%	0.136	14%	0.14	C	C	.	.	H	α-helix	trans	-67.9	-38.9	172.7	-77.9	167	0	0	0	111.7	M223 F224 E225 S230 L231 L325 W416	M223-L227 WeakPolarHBondContact O-CG 3.38Å; M223-L227 PolarHBondContact O-N 3.38Å; F224-L227 WeakPolarHBondContact O-CA 3.45Å; F224-L227 VanDerWaalsContact O-CB 3.32Å; F224-L227 WeakPolarHBondContact O-CB 3.38Å; F224-L227 PolarHBondContact O-N 3.49Å; E225-L227 VanDerWaalsContact C-N 3.29Å; E225-L227 PolarHBondContact O-N 3.5Å; L227-S230 WeakPolarHBondContact O-CB 3.3Å; L227-S230 PolarHBondContact O-N 2.78Å; L227-S230 VanDerWaalsContact O-N 3.14Å; L227-L231 HydrophobicContact CD2-CD1 4.31Å; L227-L231 VanDerWaalsContact O-CB 3.29Å; L227-L231 WeakPolarHBondContact O-CB 3.31Å; L227-L231 VanDerWaalsContact O-CG 3.28Å; L227-L231 WeakPolarHBondContact O-CG 3.35Å; L227-L231 PolarHBondContact O-N 3.31Å; L227-L325 HydrophobicContact CD1-CB 3.98Å; L227-L325 HydrophobicContact CD1-CD1 4.24Å; L227-L325 HydrophobicContact CD1-CD2 4.06Å; L227-L325 HydrophobicContact CD1-CG 4.32Å; L227-W416 HydrophobicContact CD2-CH2 3.92Å; L227-W416 HydrophobicContact CD2-CZ2 3.61Å; L227-W416 HydrophobicContact CG-CH2 4.3Å; L227-W416 HydrophobicContact CG-CZ2 4.15Å
228	E	92.3	Very high	92.1	Very high	7 Å²	7	28.3 Å²	28.3	3%	0.033	14%	0.14	C	C	.	.	H	α-helix	trans	-62.1	-50.6	176.4	-65.6	-163.1	148.7	0	0	111.2	F224 E225 S230 L231 E232 F238 H245	F224-E228 HydrophobicContact CD1-CG 4.29Å; F224-E228 HydrophobicContact CE1-CG 3.91Å; F224-E228 WeakPolarHBondContact CE1-OE1 3.26Å; F224-E228 HydrophobicContact CZ-CG 4.33Å; F224-E228 PolarHBondContact O-N 3.06Å; E225-E228 PolarHBondContact O-N 3.46Å; E228-S230 PolarHBondContact O-N 2.85Å; E228-L231 CarbonylContact O-C 3.54Å; E228-L231 PolarHBondContact O-N 2.79Å; E228-E232 PolarHBondContact O-N 2.99Å; E228-F238 HydrophobicContact CB-CB 4.06Å; E228-F238 HydrophobicContact CB-CD1 4.12Å; E228-F238 HydrophobicContact CB-CG 4.08Å; E228-F238 HydrophobicContact CG-CD1 3.68Å; E228-F238 HydrophobicContact CG-CE1 3.9Å; E228-F238 HydrophobicContact CG-CG 4.11Å; E228-H245 IonicContact OE2-CE1 3.37Å; E228-H245 PolarHBondContact OE2-CE1 2.99Å; E228-H245 IonicContact OE2-ND1 3.27Å
229	Y	89.4	Confident	91.7	Very high	49 Å²	49	27.9 Å²	27.9	19%	0.192	14%	0.141	C	C	.	.	H	α-helix	trans	-53.9	-42.6	169.7	-82.7	-61.6	0	0	0	112.5	E225 L231 W242 H245 W246 I412	E225-Y229 WeakPolarHBondContact O-CD2 3.42Å; E225-Y229 PolarHBondContact O-N 3.24Å; E225-Y229 VanDerWaalsContact O-N 3.08Å; Y229-L231 PolarHBondContact O-N 2.66Å; Y229-W242 VanDerWaalsContact OH-CA 3.24Å; Y229-W242 WeakPolarHBondContact OH-CA 3.43Å; Y229-W242 PolarHBondContact OH-O 3.02Å; Y229-H245 AromaticContact CE1-CD2 3.59Å; Y229-H245 HydrophobicContact CE2-CB 3.65Å; Y229-H245 AromaticContact CE2-CD2 3.63Å; Y229-H245 AromaticContact CE2-CG 3.6Å; Y229-H245 AromaticContact CZ-CD2 3.24Å; Y229-H245 AromaticContact CZ-CG 3.67Å; Y229-H245 PolarHBondContact OH-CD2 2.78Å; Y229-W246 HydrophobicContact CD2-CZ2 4.06Å; Y229-W246 AromaticContact CE2-CE2 3.58Å; Y229-W246 AromaticContact CE2-CZ2 3.67Å; Y229-W246 HydrophobicContact CE2-CZ2 3.67Å; Y229-W246 AromaticContact CE2-NE1 3.3Å; Y229-W246 VanDerWaalsContact CE2-NE1 3.3Å; Y229-W246 AromaticContact CZ-NE1 3.59Å; Y229-W246 PolarHBondContact OH-NE1 3.2Å; Y229-W246 VanDerWaalsContact OH-NE1 3.14Å; Y229-I412 WeakPolarHBondContact O-CD1 3.43Å
230	S	92	Very high	91.2	Very high	2 Å²	2	25.6 Å²	25.6	1%	0.014	13%	0.129	C	C	.	.	H	α-helix	trans	-65.1	-29.7	-177.5	-64.2	0	0	0	0	112.5	F226 L227 E228 H233 L408 I412 W416	F226-S230 VanDerWaalsContact O-CB 3.26Å; F226-S230 WeakPolarHBondContact O-CB 3.31Å; F226-S230 PolarHBondContact O-N 3.39Å; F226-S230 PolarHBondContact O-OG 2.99Å; L227-S230 WeakPolarHBondContact O-CB 3.3Å; L227-S230 PolarHBondContact O-N 2.78Å; L227-S230 VanDerWaalsContact O-N 3.14Å; E228-S230 PolarHBondContact O-N 2.85Å; S230-H233 PolarHBondContact O-CE1 3.39Å; S230-H233 PolarHBondContact O-ND1 2.83Å; S230-L408 WeakPolarHBondContact O-CD2 3.37Å; S230-I412 WeakPolarHBondContact OG-CG2 3.41Å; S230-W416 PolarHBondContact OG-NE1 2.74Å
231	L	93.8	Very high	90.8	Very high	18 Å²	18	25.9 Å²	25.9	9%	0.094	13%	0.131	C	C	.	.	H	α-helix	trans	-117.1	5.7	-167.2	-60.7	171.3	0	0	0	113.3	L227 E228 Y229 H233 Q234 L235 F238 L329 Y333 L408	L227-L231 HydrophobicContact CD2-CD1 4.31Å; L227-L231 VanDerWaalsContact O-CB 3.29Å; L227-L231 WeakPolarHBondContact O-CB 3.31Å; L227-L231 VanDerWaalsContact O-CG 3.28Å; L227-L231 WeakPolarHBondContact O-CG 3.35Å; L227-L231 PolarHBondContact O-N 3.31Å; E228-L231 CarbonylContact O-C 3.54Å; E228-L231 PolarHBondContact O-N 2.79Å; Y229-L231 PolarHBondContact O-N 2.66Å; L231-H233 PolarHBondContact O-N 3.29Å; L231-Q234 HydrophobicContact CD2-CG 4.4Å; L231-Q234 WeakPolarHBondContact O-CA 3.42Å; L231-Q234 WeakPolarHBondContact O-CB 3.09Å; L231-Q234 PolarHBondContact O-N 3.28Å; L231-L235 PolarHBondContact O-N 3.42Å; L231-F238 HydrophobicContact CB-CD2 3.83Å; L231-F238 HydrophobicContact CB-CE2 3.97Å; L231-L329 HydrophobicContact CD1-CD1 3.65Å; L231-L329 HydrophobicContact CD1-CD2 3.76Å; L231-L329 HydrophobicContact CD1-CG 4.31Å; L231-Y333 HydrophobicContact CD1-CE2 4.39Å; L231-L408 HydrophobicContact CD2-CD2 4.42Å
232	E	90.8	Very high	90.4	Very high	58 Å²	58	32.9 Å²	32.9	27%	0.271	16%	0.157	S	C	.	.	T	Hydrogen-bonded Turn	trans	-57	-31.7	175.1	70.7	174.7	175.6	0	0	113.4	E228 Q234 L235 F238	E228-E232 PolarHBondContact O-N 2.99Å; E232-Q234 PolarHBondContact O-N 3.47Å; E232-L235 CarbonylContact O-C 3.33Å; E232-F238 HydrophobicContact CB-CB 4.15Å
233	H	88.5	Confident	90.1	Very high	60 Å²	60	30.9 Å²	30.9	28%	0.278	14%	0.143	S	C	.	.	T	Hydrogen-bonded Turn	trans	-69.9	-18.9	174.7	72.1	-71.6	0	0	0	113.3	S230 L231	S230-H233 PolarHBondContact O-CE1 3.39Å; S230-H233 PolarHBondContact O-ND1 2.83Å; L231-H233 PolarHBondContact O-N 3.29Å
234	Q	91.6	Very high	89.7	Confident	19 Å²	19	27.9 Å²	27.9	9%	0.089	13%	0.129	C	C	.	.	T	Hydrogen-bonded Turn	trans	-93.5	-42.8	173.7	-59.8	-167.2	-7.8	0	0	111.3	L231 E232 Y333 T403 L406	L231-Q234 HydrophobicContact CD2-CG 4.4Å; L231-Q234 WeakPolarHBondContact O-CA 3.42Å; L231-Q234 WeakPolarHBondContact O-CB 3.09Å; L231-Q234 PolarHBondContact O-N 3.28Å; E232-Q234 PolarHBondContact O-N 3.47Å; Q234-Y333 PolarHBondContact OE1-OH 2.93Å; Q234-T403 HydrophobicContact CB-CG2 3.85Å; Q234-T403 PolarHBondContact NE2-O 3.19Å; Q234-T403 VanDerWaalsContact O-CG2 3.3Å; Q234-T403 WeakPolarHBondContact O-CG2 3.47Å; Q234-L406 HydrophobicContact CG-CB 4.46Å
235	L	89.4	Confident	89.4	Confident	1 Å²	1	27.4 Å²	27.4	1%	0.005	13%	0.127	C	C	.	.			trans	-122.3	107.1	-178	-68.5	-179.6	0	0	0	110.3	L231 E232 N237 F238 F332 Y333 F336	L231-L235 PolarHBondContact O-N 3.42Å; E232-L235 CarbonylContact O-C 3.33Å; L235-N237 PolarHBondContact O-N 2.98Å; L235-F238 HydrophobicContact CB-CD2 3.79Å; L235-F238 HydrophobicContact CB-CE2 4.1Å; L235-F238 HydrophobicContact CB-CG 4.31Å; L235-F238 HydrophobicContact CD1-CD2 4.21Å; L235-F238 HydrophobicContact CD1-CE2 3.63Å; L235-F238 HydrophobicContact CD1-CZ 3.97Å; L235-F238 HydrophobicContact CG-CE2 4.35Å; L235-F238 PolarHBondContact O-N 3.46Å; L235-F332 HydrophobicContact CD1-CB 4.19Å; L235-Y333 HydrophobicContact CD1-CD1 4.07Å; L235-Y333 HydrophobicContact CD1-CD2 3.73Å; L235-Y333 HydrophobicContact CD1-CE1 3.93Å; L235-Y333 HydrophobicContact CD1-CE2 3.56Å; L235-Y333 HydrophobicContact CD1-CG 3.99Å; L235-Y333 HydrophobicContact CG-CE1 4.12Å; L235-Y333 HydrophobicContact CG-CE2 4.43Å; L235-F336 HydrophobicContact CD2-CB 3.85Å; L235-F336 HydrophobicContact CD2-CD1 3.53Å; L235-F336 HydrophobicContact CD2-CD2 3.66Å; L235-F336 HydrophobicContact CD2-CE1 3.9Å; L235-F336 HydrophobicContact CD2-CE2 4.03Å; L235-F336 HydrophobicContact CD2-CG 3.39Å; L235-F336 HydrophobicContact CD2-CZ 4.13Å
236	P	84.5	Confident	89.2	Confident	21 Å²	21	31.9 Å²	31.9	14%	0.136	14%	0.143	C	C	.	.	G	3₁₀ helix	trans	-42.2	-35.7	169.9	-40.8	43.2	0	0	0	116	R168 H169 F238 S239	R168-P236 CarbonylContact O-C 3.45Å; H169-P236 WeakPolarHBondContact CE1-CB 3.39Å; H169-P236 WeakPolarHBondContact ND1-CB 3.39Å; P236-F238 PolarHBondContact O-N 3.25Å; P236-S239 WeakPolarHBondContact O-CB 2.94Å; P236-S239 PolarHBondContact O-N 2.88Å; P236-S239 VanDerWaalsContact O-N 3.12Å
237	N	83.9	Confident	89.1	Confident	30 Å²	30	32.6 Å²	32.6	16%	0.16	15%	0.149	C	C	.	.	G	3₁₀ helix	trans	-65.4	-18.8	-179.2	-70.1	-51.4	0	0	0	113.9	R168 Y170 L235	R168-N237 PolarHBondContact O-N 3.29Å; R168-N237 PolarHBondContact O-OD1 3.18Å; Y170-N237 WeakPolarHBondContact CD2-O 2.85Å; Y170-N237 HydrophobicContact CE2-CB 4.25Å; L235-N237 PolarHBondContact O-N 2.98Å
238	F	88.8	Confident	88.9	Confident	1 Å²	1	32.1 Å²	32.1	0%	0.004	15%	0.147	C	C	.	.	G	3₁₀ helix	trans	-90.3	-6	176.6	-66.9	-31.7	0	0	0	113.1	E228 L231 E232 L235 P236 E240 L329 F332 Y333	E228-F238 HydrophobicContact CB-CB 4.06Å; E228-F238 HydrophobicContact CB-CD1 4.12Å; E228-F238 HydrophobicContact CB-CG 4.08Å; E228-F238 HydrophobicContact CG-CD1 3.68Å; E228-F238 HydrophobicContact CG-CE1 3.9Å; E228-F238 HydrophobicContact CG-CG 4.11Å; L231-F238 HydrophobicContact CB-CD2 3.83Å; L231-F238 HydrophobicContact CB-CE2 3.97Å; E232-F238 HydrophobicContact CB-CB 4.15Å; L235-F238 HydrophobicContact CB-CD2 3.79Å; L235-F238 HydrophobicContact CB-CE2 4.1Å; L235-F238 HydrophobicContact CB-CG 4.31Å; L235-F238 HydrophobicContact CD1-CD2 4.21Å; L235-F238 HydrophobicContact CD1-CE2 3.63Å; L235-F238 HydrophobicContact CD1-CZ 3.97Å; L235-F238 HydrophobicContact CG-CE2 4.35Å; L235-F238 PolarHBondContact O-N 3.46Å; P236-F238 PolarHBondContact O-N 3.25Å; F238-E240 PolarHBondContact O-N 3.02Å; F238-E240 VanDerWaalsContact O-N 3.11Å; F238-L329 HydrophobicContact CE2-CD1 3.98Å; F238-L329 HydrophobicContact CZ-CD1 3.88Å; F238-F332 HydrophobicContact CD1-CD1 4.31Å; F238-F332 HydrophobicContact CE1-CB 3.89Å; F238-F332 AromaticContact CE1-CD1 3.43Å; F238-F332 HydrophobicContact CE1-CD1 3.43Å; F238-F332 VanDerWaalsContact CE1-CD1 3.43Å; F238-F332 AromaticContact CE1-CD2 3.94Å; F238-F332 HydrophobicContact CE1-CD2 3.94Å; F238-F332 AromaticContact CE1-CE1 3.85Å; F238-F332 HydrophobicContact CE1-CE1 3.85Å; F238-F332 HydrophobicContact CE1-CE2 4.33Å; F238-F332 AromaticContact CE1-CG 3.48Å; F238-F332 HydrophobicContact CE1-CG 3.48Å; F238-F332 VanDerWaalsContact CE1-CG 3.48Å; F238-F332 HydrophobicContact CE1-CZ 4.27Å; F238-F332 HydrophobicContact CZ-CB 3.61Å; F238-F332 HydrophobicContact CZ-CD1 4.09Å; F238-F332 HydrophobicContact CZ-CD2 4.08Å; F238-F332 AromaticContact CZ-CG 3.67Å; F238-F332 HydrophobicContact CZ-CG 3.67Å; F238-Y333 HydrophobicContact CE2-CE2 4.33Å
239	S	86.8	Confident	88.8	Confident	29 Å²	29	31.8 Å²	31.8	20%	0.203	15%	0.145	C	C	.	.			trans	-74.7	104.9	172.5	-169.1	0	0	0	0	107.7	Y170 G171 P236	Y170-S239 CarbonylContact C-O 3.28Å; Y170-S239 VanDerWaalsContact C-O 3.28Å; Y170-S239 WeakPolarHBondContact CA-O 3.33Å; Y170-S239 PolarHBondContact N-O 3.17Å; G171-S239 WeakPolarHBondContact CA-O 3.44Å; G171-S239 PolarHBondContact N-O 3.46Å; P236-S239 WeakPolarHBondContact O-CB 2.94Å; P236-S239 PolarHBondContact O-N 2.88Å; P236-S239 VanDerWaalsContact O-N 3.12Å
240	E	85.3	Confident	88.9	Confident	23 Å²	23	29.9 Å²	29.9	11%	0.107	14%	0.139	C	C	.	.			trans	-130.3	175.5	175.6	-48.2	-163.2	156.2	0	0	110.4	F196 F238 D244	F196-E240 WeakPolarHBondContact CZ-OE2 3.27Å; F238-E240 PolarHBondContact O-N 3.02Å; F238-E240 VanDerWaalsContact O-N 3.11Å; E240-D244 HydrophobicContact CB-CB 4.36Å
241	C	87.3	Confident	88.9	Confident	7 Å²	7	35.3 Å²	35.3	5%	0.047	17%	0.167	C	C	.	.			trans	-80	151.3	-176.8	-73.1	0	0	0	0	112.4	C174 W243 D244 H245	C174-C241 WeakPolarHBondContact CA-SG 3.38Å; C174-C241 HydrophobicContact CB-CB 3.67Å; C174-C241 WeakPolarHBondContact CB-SG 3.07Å; C174-C241 WeakPolarHBondContact SG-CA 3.31Å; C174-C241 WeakPolarHBondContact SG-CB 3.43Å; C174-C241 CovalentContact SG-SG 2.06Å; C174-C241 PolarHBondContact SG-SG 3.19Å; C241-W243 PolarHBondContact O-N 3.02Å; C241-D244 HydrophobicContact CB-CB 4.11Å; C241-D244 WeakPolarHBondContact O-CA 3.35Å; C241-D244 WeakPolarHBondContact O-CB 3.38Å; C241-D244 PolarHBondContact O-N 2.93Å; C241-H245 PolarHBondContact O-CD2 2.98Å; C241-H245 PolarHBondContact O-N 3.35Å
242	W	88.3	Confident	88.9	Confident	146 Å²	146	37.6 Å²	37.6	55%	0.553	18%	0.181	S	C	*	.	H	α-helix	trans	-61.2	-35.8	-174.7	72.1	-93	0	0	0	113.5	Y229 D244 W246 I247	Y229-W242 VanDerWaalsContact OH-CA 3.24Å; Y229-W242 WeakPolarHBondContact OH-CA 3.43Å; Y229-W242 PolarHBondContact OH-O 3.02Å; W242-D244 VanDerWaalsContact C-N 3.32Å; W242-W246 PolarHBondContact O-N 2.98Å; W242-I247 HydrophobicContact CH2-CD1 4.11Å; W242-I247 HydrophobicContact CZ3-CD1 3.94Å; W242-I247 HydrophobicContact CZ3-CG1 4.49Å
243	W	88.6	Confident	89	Confident	16 Å²	16	34.9 Å²	34.9	6%	0.061	17%	0.169	C	C	.	.	H	α-helix	trans	-77.6	-22	177.7	61.8	-98.4	0	0	0	111.8	C174 I176 N188 V189 C241 I247 M248	C174-W243 PolarHBondContact O-NE1 3.09Å; I176-W243 HydrophobicContact CD1-CB 4.16Å; I176-W243 HydrophobicContact CD1-CD2 4.21Å; I176-W243 HydrophobicContact CD1-CG 3.88Å; I176-W243 HydrophobicContact CG1-CD2 3.84Å; I176-W243 HydrophobicContact CG1-CG 3.81Å; I176-W243 HydrophobicContact CG1-CZ2 4.43Å; N188-W243 HydrophobicContact CB-CZ2 4.44Å; V189-W243 HydrophobicContact CG2-CH2 3.99Å; V189-W243 HydrophobicContact CG2-CZ2 4.4Å; C241-W243 PolarHBondContact O-N 3.02Å; W243-I247 HydrophobicContact CB-CD1 4.12Å; W243-I247 WeakPolarHBondContact O-CA 2.94Å; W243-I247 VanDerWaalsContact O-CB 3.26Å; W243-I247 WeakPolarHBondContact O-CB 3.37Å; W243-I247 PolarHBondContact O-N 3.37Å; W243-M248 HydrophobicContact CE3-CE 4.44Å; W243-M248 HydrophobicContact CH2-CE 4.09Å; W243-M248 HydrophobicContact CZ3-CE 3.54Å; W243-M248 HydrophobicContact CZ3-SD 4.18Å; W243-M248 PolarHBondContact O-N 2.79Å
244	D	87.4	Confident	89.3	Confident	0 Å²	0	32 Å²	32	0%	0	16%	0.156	C	C	.	.	I	π-helix	trans	-63.1	-62.3	173.2	-155	-4.1	0	0	0	108.4	K192 F196 E240 C241 W242 W246 M248 D249	K192-D244 WeakPolarHBondContact CD-OD2 3.32Å; K192-D244 WeakPolarHBondContact CE-OD2 3.42Å; K192-D244 IonicContact NZ-OD2 3.95Å; K192-D244 PolarHBondContact NZ-OD2 2.98Å; F196-D244 WeakPolarHBondContact CE1-OD1 3.43Å; E240-D244 HydrophobicContact CB-CB 4.36Å; C241-D244 HydrophobicContact CB-CB 4.11Å; C241-D244 WeakPolarHBondContact O-CA 3.35Å; C241-D244 WeakPolarHBondContact O-CB 3.38Å; C241-D244 PolarHBondContact O-N 2.93Å; W242-D244 VanDerWaalsContact C-N 3.32Å; D244-W246 PolarHBondContact O-N 2.59Å; D244-M248 CarbonylContact O-C 3.56Å; D244-M248 WeakPolarHBondContact O-CA 3.42Å; D244-M248 VanDerWaalsContact O-CB 3.31Å; D244-M248 WeakPolarHBondContact O-CB 3.3Å; D244-M248 PolarHBondContact O-N 3.02Å; D244-M248 VanDerWaalsContact O-N 3.09Å; D244-M248 WeakPolarHBondContact OD1-CE 3.35Å; D244-D249 PolarHBondContact O-N 3.28Å
245	H	87.8	Confident	89.5	Confident	0 Å²	0	31.7 Å²	31.7	0%	0	16%	0.157	C	C	.	.	I	π-helix	trans	-52	-57.3	176.8	-70.9	-65.3	0	0	0	113.7	E225 E228 Y229 C241 D249 V250	E225-H245 IonicContact OE2-CE1 3.89Å; E225-H245 IonicContact OE2-CG 3.4Å; E225-H245 IonicContact OE2-ND1 2.66Å; E225-H245 PolarHBondContact OE2-ND1 3.45Å; E228-H245 IonicContact OE2-CE1 3.37Å; E228-H245 PolarHBondContact OE2-CE1 2.99Å; E228-H245 IonicContact OE2-ND1 3.27Å; Y229-H245 AromaticContact CE1-CD2 3.59Å; Y229-H245 HydrophobicContact CE2-CB 3.65Å; Y229-H245 AromaticContact CE2-CD2 3.63Å; Y229-H245 AromaticContact CE2-CG 3.6Å; Y229-H245 AromaticContact CZ-CD2 3.24Å; Y229-H245 AromaticContact CZ-CG 3.67Å; Y229-H245 PolarHBondContact OH-CD2 2.78Å; C241-H245 PolarHBondContact O-CD2 2.98Å; C241-H245 PolarHBondContact O-N 3.35Å; H245-D249 WeakPolarHBondContact O-CB 3.42Å; H245-V250 WeakPolarHBondContact O-CG2 3.03Å; H245-V250 PolarHBondContact O-N 2.84Å
246	W	90.4	Very high	89.8	Confident	95 Å²	95	35.9 Å²	35.9	36%	0.36	18%	0.179	S	C	.	.	I	π-helix	trans	-86.4	-38.6	-166.6	-64.4	115.6	0	0	0	113.9	V222 Y229 W242 D244 V250 L251	V222-W246 HydrophobicContact CG1-CZ3 4.23Å; Y229-W246 HydrophobicContact CD2-CZ2 4.06Å; Y229-W246 AromaticContact CE2-CE2 3.58Å; Y229-W246 AromaticContact CE2-CZ2 3.67Å; Y229-W246 HydrophobicContact CE2-CZ2 3.67Å; Y229-W246 AromaticContact CE2-NE1 3.3Å; Y229-W246 VanDerWaalsContact CE2-NE1 3.3Å; Y229-W246 AromaticContact CZ-NE1 3.59Å; Y229-W246 PolarHBondContact OH-NE1 3.2Å; Y229-W246 VanDerWaalsContact OH-NE1 3.14Å; W242-W246 PolarHBondContact O-N 2.98Å; D244-W246 PolarHBondContact O-N 2.59Å; W246-V250 HydrophobicContact CE3-CG2 3.82Å; W246-V250 HydrophobicContact CZ3-CG2 4.09Å; W246-L251 WeakPolarHBondContact O-CG 3.23Å; W246-L251 PolarHBondContact O-N 3.37Å
247	I	90.5	Very high	90.4	Very high	77 Å²	77	34.9 Å²	34.9	40%	0.395	17%	0.173	S	C	.	.	I	π-helix	trans	-92.9	-54.5	-176.1	-55.4	178	0	0	0	109.1	W242 W243 L251 V252	W242-I247 HydrophobicContact CH2-CD1 4.11Å; W242-I247 HydrophobicContact CZ3-CD1 3.94Å; W242-I247 HydrophobicContact CZ3-CG1 4.49Å; W243-I247 HydrophobicContact CB-CD1 4.12Å; W243-I247 WeakPolarHBondContact O-CA 2.94Å; W243-I247 VanDerWaalsContact O-CB 3.26Å; W243-I247 WeakPolarHBondContact O-CB 3.37Å; W243-I247 PolarHBondContact O-N 3.37Å; I247-L251 WeakPolarHBondContact O-CB 3.45Å; I247-V252 WeakPolarHBondContact O-CG2 3.43Å; I247-V252 PolarHBondContact O-N 3.36Å
248	M	89.2	Confident	91.1	Very high	16 Å²	16	33.4 Å²	33.4	8%	0.079	17%	0.165	C	C	.	.	I	π-helix	trans	-71.9	-50.2	-175.5	-168.8	146.8	61.8	0	0	111.4	K192 F196 V197 W243 D244 V252 C253	K192-M248 HydrophobicContact CB-CE 3.38Å; K192-M248 HydrophobicContact CB-SD 4.31Å; K192-M248 HydrophobicContact CD-CE 4.34Å; K192-M248 HydrophobicContact CG-CE 3.81Å; F196-M248 HydrophobicContact CD1-CE 4.49Å; F196-M248 HydrophobicContact CE1-CE 4.43Å; V197-M248 HydrophobicContact CG2-CG 4.18Å; V197-M248 HydrophobicContact CG2-SD 3.84Å; W243-M248 HydrophobicContact CE3-CE 4.44Å; W243-M248 HydrophobicContact CH2-CE 4.09Å; W243-M248 HydrophobicContact CZ3-CE 3.54Å; W243-M248 HydrophobicContact CZ3-SD 4.18Å; W243-M248 PolarHBondContact O-N 2.79Å; D244-M248 CarbonylContact O-C 3.56Å; D244-M248 WeakPolarHBondContact O-CA 3.42Å; D244-M248 VanDerWaalsContact O-CB 3.31Å; D244-M248 WeakPolarHBondContact O-CB 3.3Å; D244-M248 PolarHBondContact O-N 3.02Å; D244-M248 VanDerWaalsContact O-N 3.09Å; D244-M248 WeakPolarHBondContact OD1-CE 3.35Å; M248-V252 CarbonylContact O-C 3.52Å; M248-V252 WeakPolarHBondContact O-CB 3.46Å; M248-V252 PolarHBondContact O-N 2.92Å; M248-C253 WeakPolarHBondContact O-CB 3.25Å; M248-C253 PolarHBondContact O-N 3.06Å; M248-C253 PolarHBondContact O-SG 3.33Å
249	D	90.6	Very high	91.5	Very high	0 Å²	0	39.2 Å²	39.2	0%	0	19%	0.188	C	C	.	.	I	π-helix	trans	-79.1	-68.1	-177.2	-65.7	-36.4	0	0	0	112.4	F196 H200 E225 D244 H245 L251 C253 N254	F196-D249 WeakPolarHBondContact CE1-OD1 3.35Å; F196-D249 WeakPolarHBondContact CE1-OD2 3.46Å; F196-D249 WeakPolarHBondContact CZ-OD1 3.38Å; F196-D249 VanDerWaalsContact CZ-OD2 3.23Å; F196-D249 WeakPolarHBondContact CZ-OD2 3.27Å; H200-D249 IonicContact CD2-OD1 2.88Å; H200-D249 IonicContact CG-OD1 2.77Å; H200-D249 IonicContact ND1-OD1 3.71Å; E225-D249 WeakPolarHBondContact OE1-CB 3.34Å; D244-D249 PolarHBondContact O-N 3.28Å; H245-D249 WeakPolarHBondContact O-CB 3.42Å; D249-L251 PolarHBondContact O-N 3.26Å; D249-C253 PolarHBondContact O-N 3.48Å; D249-N254 VanDerWaalsContact C-CG 3.46Å; D249-N254 WeakPolarHBondContact O-CA 3.36Å; D249-N254 WeakPolarHBondContact O-CB 3.31Å; D249-N254 PolarHBondContact O-N 3.43Å; D249-N254 PolarHBondContact O-ND2 2.96Å; D249-N254 PolarHBondContact O-OD1 3.39Å
250	V	92.3	Very high	92	Very high	9 Å²	9	40 Å²	40	6%	0.055	19%	0.192	C	C	.	.	I	π-helix	trans	-56.9	-53.2	-175.1	178.6	0	0	0	0	112.2	V222 E225 H245 W246 G255	V222-V250 HydrophobicContact CG2-CG1 3.82Å; V222-V250 HydrophobicContact CG2-CG2 4.45Å; E225-V250 HydrophobicContact CB-CG2 4.29Å; E225-V250 HydrophobicContact CG-CG2 3.44Å; E225-V250 VanDerWaalsContact CG-CG2 3.44Å; H245-V250 WeakPolarHBondContact O-CG2 3.03Å; H245-V250 PolarHBondContact O-N 2.84Å; W246-V250 HydrophobicContact CE3-CG2 3.82Å; W246-V250 HydrophobicContact CZ3-CG2 4.09Å; V250-G255 WeakPolarHBondContact O-CA 3.04Å; V250-G255 PolarHBondContact O-N 3.36Å
251	L	92.3	Very high	92.5	Very high	115 Å²	115	38.9 Å²	38.9	60%	0.602	19%	0.187	S	C	*	.	I	π-helix	trans	-82.9	-48	-169.5	-67	177.2	0	0	0	112.7	W246 I247 D249	W246-L251 WeakPolarHBondContact O-CG 3.23Å; W246-L251 PolarHBondContact O-N 3.37Å; I247-L251 WeakPolarHBondContact O-CB 3.45Å; D249-L251 PolarHBondContact O-N 3.26Å
252	V	92	Very high	92.9	Very high	67 Å²	67	41 Å²	41	41%	0.406	20%	0.197	S	C	.	.	I	π-helix	trans	-85.8	-70.6	-173.8	177.8	0	0	0	0	110.8	I247 M248 L256	I247-V252 WeakPolarHBondContact O-CG2 3.43Å; I247-V252 PolarHBondContact O-N 3.36Å; M248-V252 CarbonylContact O-C 3.52Å; M248-V252 WeakPolarHBondContact O-CB 3.46Å; M248-V252 PolarHBondContact O-N 2.92Å; V252-L256 HydrophobicContact CG1-CD1 4.05Å; V252-L256 WeakPolarHBondContact O-CB 3.37Å; V252-L256 WeakPolarHBondContact O-CD1 3.5Å; V252-L256 WeakPolarHBondContact O-CG 3.47Å; V252-L256 PolarHBondContact O-N 3.4Å
253	C	93.3	Very high	93.2	Very high	1 Å²	1	38.5 Å²	38.5	1%	0.007	19%	0.19	C	C	.	.	I	π-helix	trans	-66.9	-57.4	-170.8	-60.2	0	0	0	0	111.9	H200 M248 D249 G257	H200-C253 HydrophobicContact CB-CB 3.51Å; M248-C253 WeakPolarHBondContact O-CB 3.25Å; M248-C253 PolarHBondContact O-N 3.06Å; M248-C253 PolarHBondContact O-SG 3.33Å; D249-C253 PolarHBondContact O-N 3.48Å; C253-G257 PolarHBondContact O-N 2.83Å
254	N	95.6	Very high	93.4	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	20%	0.198	C	C	.	.	I	π-helix	trans	-69	-50.5	-175.4	-53.8	-10.6	0	0	0	109.5	W204 S221 E225 D249 L256 G257 I258	W204-N254 VanDerWaalsContact CD1-CB 3.48Å; W204-N254 HydrophobicContact CD2-CB 4.01Å; W204-N254 HydrophobicContact CG-CB 3.73Å; W204-N254 PolarHBondContact NE1-ND2 2.91Å; W204-N254 PolarHBondContact NE1-OD1 2.87Å; S221-N254 VanDerWaalsContact OG-CB 3.23Å; S221-N254 WeakPolarHBondContact OG-CB 3.44Å; S221-N254 PolarHBondContact OG-ND2 3.29Å; E225-N254 PolarHBondContact OE1-ND2 3.39Å; D249-N254 VanDerWaalsContact C-CG 3.46Å; D249-N254 WeakPolarHBondContact O-CA 3.36Å; D249-N254 WeakPolarHBondContact O-CB 3.31Å; D249-N254 PolarHBondContact O-N 3.43Å; D249-N254 PolarHBondContact O-ND2 2.96Å; D249-N254 PolarHBondContact O-OD1 3.39Å; N254-L256 PolarHBondContact O-N 3.45Å; N254-G257 PolarHBondContact O-N 3.46Å; N254-I258 WeakPolarHBondContact O-CB 3.49Å; N254-I258 WeakPolarHBondContact O-CG1 3.2Å; N254-I258 PolarHBondContact O-N 2.88Å
255	G	95.8	Very high	93.6	Very high	12 Å²	12	40 Å²	40	12%	0.124	20%	0.2	C	C	.	.	H	α-helix	trans	-57.4	-47.5	178.8	0	0	0	0	0	113.6	V250 I258 Y259	V250-G255 WeakPolarHBondContact O-CA 3.04Å; V250-G255 PolarHBondContact O-N 3.36Å; G255-I258 PolarHBondContact O-N 2.97Å; G255-Y259 WeakPolarHBondContact O-CB 3.03Å; G255-Y259 PolarHBondContact O-N 3.23Å
256	L	95.8	Very high	93.7	Very high	88 Å²	88	44.3 Å²	44.3	46%	0.461	22%	0.221	S	C	.	.	H	α-helix	trans	-68.5	-39.6	176.5	-65.5	173.7	0	0	0	111.8	F201 V252 N254 I258 Y259 C260	F201-L256 HydrophobicContact CD2-CB 4.01Å; F201-L256 HydrophobicContact CE2-CB 3.89Å; V252-L256 HydrophobicContact CG1-CD1 4.05Å; V252-L256 WeakPolarHBondContact O-CB 3.37Å; V252-L256 WeakPolarHBondContact O-CD1 3.5Å; V252-L256 WeakPolarHBondContact O-CG 3.47Å; V252-L256 PolarHBondContact O-N 3.4Å; N254-L256 PolarHBondContact O-N 3.45Å; L256-I258 VanDerWaalsContact C-N 3.34Å; L256-I258 PolarHBondContact O-N 3.07Å; L256-Y259 PolarHBondContact O-N 3.06Å; L256-C260 WeakPolarHBondContact O-CB 3.46Å; L256-C260 PolarHBondContact O-N 3.16Å; L256-C260 PolarHBondContact O-SG 3.5Å; L256-C260 VanDerWaalsContact O-SG 3.42Å
257	G	97.1	Very high	93.6	Very high	0 Å²	0	46.2 Å²	46.2	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-58.6	-46.3	175.3	0	0	0	0	0	111.7	Y205 C253 N254 G261	Y205-G257 WeakPolarHBondContact CA-O 3.46Å; C253-G257 PolarHBondContact O-N 2.83Å; N254-G257 PolarHBondContact O-N 3.46Å; G257-G261 PolarHBondContact O-N 3.38Å
258	I	97.6	Very high	93.4	Very high	0 Å²	0	43.4 Å²	43.4	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-62.6	-46.1	175.4	-64.3	164.6	0	0	0	110.6	W204 T208 W214 C217 M218 N254 G255 L256 C260 G261 M262	W204-I258 HydrophobicContact CB-CG1 4.28Å; W204-I258 HydrophobicContact CD2-CD1 4.3Å; W204-I258 HydrophobicContact CD2-CG1 4.32Å; W204-I258 HydrophobicContact CE3-CD1 3.68Å; W204-I258 HydrophobicContact CE3-CG1 3.68Å; W204-I258 HydrophobicContact CZ3-CD1 4.12Å; W204-I258 HydrophobicContact CZ3-CG1 4.48Å; T208-I258 HydrophobicContact CG2-CG2 4.38Å; T208-I258 WeakPolarHBondContact OG1-CA 3.13Å; W214-I258 HydrophobicContact CD2-CG2 4.35Å; W214-I258 HydrophobicContact CE3-CG2 3.49Å; W214-I258 VanDerWaalsContact CE3-CG2 3.49Å; W214-I258 HydrophobicContact CZ3-CB 4.31Å; W214-I258 HydrophobicContact CZ3-CG2 3.62Å; C217-I258 HydrophobicContact CB-CD1 3.87Å; C217-I258 HydrophobicContact CB-CG1 3.95Å; C217-I258 HydrophobicContact CB-CG2 3.9Å; M218-I258 HydrophobicContact CG-CD1 4.43Å; M218-I258 HydrophobicContact SD-CD1 3.57Å; M218-I258 VanDerWaalsContact SD-CD1 3.57Å; N254-I258 WeakPolarHBondContact O-CB 3.49Å; N254-I258 WeakPolarHBondContact O-CG1 3.2Å; N254-I258 PolarHBondContact O-N 2.88Å; G255-I258 PolarHBondContact O-N 2.97Å; L256-I258 VanDerWaalsContact C-N 3.34Å; L256-I258 PolarHBondContact O-N 3.07Å; I258-C260 PolarHBondContact O-N 3.38Å; I258-G261 PolarHBondContact O-N 3.29Å; I258-M262 HydrophobicContact CG2-CG 4.33Å; I258-M262 WeakPolarHBondContact O-CG 3.28Å; I258-M262 PolarHBondContact O-N 3.42Å
259	Y	96.9	Very high	93.1	Very high	123 Å²	123	43.4 Å²	43.4	48%	0.482	22%	0.215	S	C	.	.	H	α-helix	trans	-58.5	-50.5	178.1	175.6	-94.5	0	0	0	112.4	G255 L256 G261 M262 K263	G255-Y259 WeakPolarHBondContact O-CB 3.03Å; G255-Y259 PolarHBondContact O-N 3.23Å; L256-Y259 PolarHBondContact O-N 3.06Å; Y259-G261 VanDerWaalsContact C-N 3.29Å; Y259-G261 PolarHBondContact O-N 3.22Å; Y259-M262 PolarHBondContact O-N 2.95Å; Y259-K263 HydrophobicContact CD1-CG 4.47Å; Y259-K263 HydrophobicContact CE1-CG 4Å; Y259-K263 HydrophobicContact CE2-CG 4.41Å; Y259-K263 PolarHBondContact O-N 3.2Å
260	C	97.3	Very high	92.5	Very high	45 Å²	45	49.3 Å²	49.3	30%	0.304	25%	0.246	S	C	.	.	H	α-helix	trans	-61.5	-38.9	176.7	-72.5	0	0	0	0	111.8	F201 Y205 L256 I258 K263 T264	F201-C260 HydrophobicContact CE2-CB 4.46Å; F201-C260 HydrophobicContact CZ-CB 4.16Å; Y205-C260 HydrophobicContact CD2-CB 4.15Å; L256-C260 WeakPolarHBondContact O-CB 3.46Å; L256-C260 PolarHBondContact O-N 3.16Å; L256-C260 PolarHBondContact O-SG 3.5Å; L256-C260 VanDerWaalsContact O-SG 3.42Å; I258-C260 PolarHBondContact O-N 3.38Å; C260-K263 PolarHBondContact O-N 2.85Å; C260-T264 PolarHBondContact O-N 3.02Å; C260-T264 PolarHBondContact O-OG1 2.9Å
261	G	96.4	Very high	91.8	Very high	0 Å²	0	51.1 Å²	51.1	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-58.3	-54.8	173.1	0	0	0	0	0	111	G257 I258 Y259 K263 T264 L265	G257-G261 PolarHBondContact O-N 3.38Å; I258-G261 PolarHBondContact O-N 3.29Å; Y259-G261 VanDerWaalsContact C-N 3.29Å; Y259-G261 PolarHBondContact O-N 3.22Å; G261-K263 VanDerWaalsContact C-N 3.31Å; G261-K263 PolarHBondContact O-N 2.97Å; G261-T264 WeakPolarHBondContact O-CA 3.37Å; G261-T264 VanDerWaalsContact O-CB 3.31Å; G261-T264 WeakPolarHBondContact O-CB 3.35Å; G261-T264 PolarHBondContact O-N 3.45Å; G261-L265 WeakPolarHBondContact O-CG 3.35Å; G261-L265 PolarHBondContact O-N 3.4Å
262	M	95	Very high	91.2	Very high	51 Å²	51	49.6 Å²	49.6	25%	0.251	25%	0.249	S	C	.	.	H	α-helix	trans	-58.7	-39.8	179.1	-69.6	-51.6	-65.7	0	0	112.8	T208 W214 I258 Y259 T264 L265 E266	T208-M262 HydrophobicContact CG2-CG 3.99Å; T208-M262 HydrophobicContact CG2-SD 3.68Å; W214-M262 HydrophobicContact CB-CE 4.17Å; W214-M262 HydrophobicContact CB-CG 4.34Å; W214-M262 HydrophobicContact CB-SD 4.32Å; W214-M262 HydrophobicContact CE3-CG 3.82Å; I258-M262 HydrophobicContact CG2-CG 4.33Å; I258-M262 WeakPolarHBondContact O-CG 3.28Å; I258-M262 PolarHBondContact O-N 3.42Å; Y259-M262 PolarHBondContact O-N 2.95Å; M262-T264 VanDerWaalsContact C-N 3.3Å; M262-T264 PolarHBondContact O-N 2.68Å; M262-L265 HydrophobicContact CE-CD1 4.5Å; M262-L265 PolarHBondContact O-N 3.36Å; M262-L265 HydrophobicContact SD-CD1 3.85Å; M262-E266 PolarHBondContact O-N 3.37Å
263	K	95.3	Very high	90.7	Very high	94 Å²	94	46.8 Å²	46.8	41%	0.409	23%	0.231	S	C	.	.	H	α-helix	trans	-63.3	-36.5	174.2	-73.8	-61.7	177.2	-169.7	0	113	Y259 C260 G261 E266 W267	Y259-K263 HydrophobicContact CD1-CG 4.47Å; Y259-K263 HydrophobicContact CE1-CG 4Å; Y259-K263 HydrophobicContact CE2-CG 4.41Å; Y259-K263 PolarHBondContact O-N 3.2Å; C260-K263 PolarHBondContact O-N 2.85Å; G261-K263 VanDerWaalsContact C-N 3.31Å; G261-K263 PolarHBondContact O-N 2.97Å; K263-E266 WeakPolarHBondContact CD-OE2 3.4Å; K263-E266 IonicContact NZ-OE2 2.85Å; K263-E266 PolarHBondContact NZ-OE2 3.29Å; K263-E266 PolarHBondContact O-N 2.76Å; K263-W267 WeakPolarHBondContact O-CB 3.24Å; K263-W267 PolarHBondContact O-N 3.47Å
264	T	93.2	Very high	90.2	Very high	36 Å²	36	53.2 Å²	53.2	22%	0.221	26%	0.259	C	S	.	.	H	α-helix	trans	-66.1	-41.1	173.2	-57.2	0	0	0	0	111.4	L209 C260 G261 M262 W267 L268	L209-T264 HydrophobicContact CD2-CG2 3.96Å; C260-T264 PolarHBondContact O-N 3.02Å; C260-T264 PolarHBondContact O-OG1 2.9Å; G261-T264 WeakPolarHBondContact O-CA 3.37Å; G261-T264 VanDerWaalsContact O-CB 3.31Å; G261-T264 WeakPolarHBondContact O-CB 3.35Å; G261-T264 PolarHBondContact O-N 3.45Å; M262-T264 VanDerWaalsContact C-N 3.3Å; M262-T264 PolarHBondContact O-N 2.68Å; T264-W267 PolarHBondContact O-N 2.94Å; T264-L268 HydrophobicContact CG2-CD1 4.29Å; T264-L268 WeakPolarHBondContact O-CG 3.47Å; T264-L268 PolarHBondContact O-N 3.46Å
265	L	91.4	Very high	89.7	Confident	10 Å²	10	53.4 Å²	53.4	5%	0.052	26%	0.26	C	S	.	.	H	α-helix	trans	-65.9	-39.6	176.5	-56.3	176.8	0	0	0	112.5	T208 L209 R212 G261 M262 L268 S269 W300	T208-L265 HydrophobicContact CG2-CD1 4.22Å; L209-L265 HydrophobicContact CB-CD2 4.46Å; L209-L265 HydrophobicContact CD2-CD2 3.66Å; L209-L265 HydrophobicContact CD2-CG 4.24Å; R212-L265 HydrophobicContact CB-CD1 3.87Å; R212-L265 HydrophobicContact CG-CD1 4.09Å; R212-L265 HydrophobicContact CG-CD2 4.26Å; G261-L265 WeakPolarHBondContact O-CG 3.35Å; G261-L265 PolarHBondContact O-N 3.4Å; M262-L265 HydrophobicContact CE-CD1 4.5Å; M262-L265 PolarHBondContact O-N 3.36Å; M262-L265 HydrophobicContact SD-CD1 3.85Å; L265-L268 PolarHBondContact O-N 3.03Å; L265-S269 VanDerWaalsContact O-CB 3.3Å; L265-S269 WeakPolarHBondContact O-CB 3.49Å; L265-S269 PolarHBondContact O-N 2.98Å; L265-S269 PolarHBondContact O-OG 3.43Å; L265-W300 HydrophobicContact CB-CZ2 4.06Å; L265-W300 HydrophobicContact CD2-CH2 3.38Å; L265-W300 HydrophobicContact CD2-CZ2 3.19Å; L265-W300 HydrophobicContact CG-CZ2 4.15Å
266	E	88.8	Confident	89.2	Confident	92 Å²	92	56.3 Å²	56.3	43%	0.43	27%	0.27	S	S	.	.	H	α-helix	trans	-58.4	-50.5	173.2	-175.1	174.5	-161.5	0	0	109.9	M262 K263 L268 S269 L270	M262-E266 PolarHBondContact O-N 3.37Å; K263-E266 WeakPolarHBondContact CD-OE2 3.4Å; K263-E266 IonicContact NZ-OE2 2.85Å; K263-E266 PolarHBondContact NZ-OE2 3.29Å; K263-E266 PolarHBondContact O-N 2.76Å; E266-L268 PolarHBondContact O-N 3.3Å; E266-S269 PolarHBondContact O-N 3.43Å; E266-S269 VanDerWaalsContact O-N 3.15Å; E266-S269 PolarHBondContact O-OG 2.7Å; E266-L270 HydrophobicContact CG-CD1 4.27Å; E266-L270 WeakPolarHBondContact O-CG 3.4Å; E266-L270 PolarHBondContact O-N 2.99Å; E266-L270 VanDerWaalsContact O-N 3.15Å
267	W	88.4	Confident	88.5	Confident	135 Å²	135	52.5 Å²	52.5	51%	0.511	25%	0.252	S	S	.	.	H	α-helix	trans	-59.4	-43.1	176.3	176.6	84.6	0	0	0	113.4	K263 T264 S269 K271	K263-W267 WeakPolarHBondContact O-CB 3.24Å; K263-W267 PolarHBondContact O-N 3.47Å; T264-W267 PolarHBondContact O-N 2.94Å; W267-S269 VanDerWaalsContact C-N 3.3Å; W267-S269 PolarHBondContact O-N 3Å; W267-K271 VanDerWaalsContact CD2-CE 3.43Å; W267-K271 VanDerWaalsContact CE2-NZ 3.29Å; W267-K271 HydrophobicContact CH2-CD 4.42Å; W267-K271 HydrophobicContact CZ2-CD 4.46Å; W267-K271 HydrophobicContact CZ3-CD 4.44Å; W267-K271 VanDerWaalsContact CZ3-CE 3.43Å; W267-K271 WeakPolarHBondContact O-CG 3.45Å
268	L	86.8	Confident	88	Confident	17 Å²	17	56 Å²	56	9%	0.089	27%	0.27	C	S	.	.	H	α-helix	trans	-65.2	-33.6	176.5	-73.9	174.5	0	0	0	112.3	T264 L265 E266 Y273 W300	T264-L268 HydrophobicContact CG2-CD1 4.29Å; T264-L268 WeakPolarHBondContact O-CG 3.47Å; T264-L268 PolarHBondContact O-N 3.46Å; L265-L268 PolarHBondContact O-N 3.03Å; E266-L268 PolarHBondContact O-N 3.3Å; L268-Y273 PolarHBondContact O-OH 2.98Å; L268-W300 HydrophobicContact CB-CD2 3.84Å; L268-W300 HydrophobicContact CB-CE3 4.08Å; L268-W300 HydrophobicContact CB-CG 4.28Å; L268-W300 HydrophobicContact CB-CH2 4.47Å; L268-W300 HydrophobicContact CB-CZ2 4.32Å; L268-W300 HydrophobicContact CB-CZ3 4.37Å; L268-W300 HydrophobicContact CD1-CE3 4.1Å; L268-W300 HydrophobicContact CD1-CH2 3.62Å; L268-W300 HydrophobicContact CD1-CZ2 4.18Å; L268-W300 HydrophobicContact CD1-CZ3 3.59Å
269	S	82.6	Confident	87.3	Confident	16 Å²	16	66.5 Å²	66.5	11%	0.112	31%	0.31	C	S	.	.	H	α-helix	trans	-77.3	-26.4	-177.6	72.4	0	0	0	0	114.5	L265 E266 W267 K271 R302	L265-S269 VanDerWaalsContact O-CB 3.3Å; L265-S269 WeakPolarHBondContact O-CB 3.49Å; L265-S269 PolarHBondContact O-N 2.98Å; L265-S269 PolarHBondContact O-OG 3.43Å; E266-S269 PolarHBondContact O-N 3.43Å; E266-S269 VanDerWaalsContact O-N 3.15Å; E266-S269 PolarHBondContact O-OG 2.7Å; W267-S269 VanDerWaalsContact C-N 3.3Å; W267-S269 PolarHBondContact O-N 3Å; S269-K271 VanDerWaalsContact C-N 3.3Å; S269-R302 PolarHBondContact OG-NE 3.48Å; S269-R302 PolarHBondContact OG-NH2 3.43Å
270	L	77.9	Confident	86.7	Confident	124 Å²	124	65.3 Å²	65.3	65%	0.649	31%	0.312	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.1	-8.8	177.9	-65.7	172.3	0	0	0	112.7	E266	E266-L270 HydrophobicContact CG-CD1 4.27Å; E266-L270 WeakPolarHBondContact O-CG 3.4Å; E266-L270 PolarHBondContact O-N 2.99Å; E266-L270 VanDerWaalsContact O-N 3.15Å
271	K	78.3	Confident	86.3	Confident	48 Å²	48	64.1 Å²	64.1	21%	0.209	30%	0.302	C	S	.	.			trans	-77.8	134.6	-179.8	-79.3	-178.6	-173.3	-66.8	0	112.1	W267 S269 Y273 F293	W267-K271 VanDerWaalsContact CD2-CE 3.43Å; W267-K271 VanDerWaalsContact CE2-NZ 3.29Å; W267-K271 HydrophobicContact CH2-CD 4.42Å; W267-K271 HydrophobicContact CZ2-CD 4.46Å; W267-K271 HydrophobicContact CZ3-CD 4.44Å; W267-K271 VanDerWaalsContact CZ3-CE 3.43Å; W267-K271 WeakPolarHBondContact O-CG 3.45Å; S269-K271 VanDerWaalsContact C-N 3.3Å; K271-Y273 HydrophobicContact CB-CD2 4.5Å; K271-Y273 HydrophobicContact CB-CE2 4.01Å; K271-Y273 WeakPolarHBondContact O-CD2 3.34Å; K271-Y273 WeakPolarHBondContact O-CE2 3.13Å; K271-F293 HydrophobicContact CD-CE1 4.41Å
272	T	78.9	Confident	85.9	Confident	83 Å²	83	70 Å²	70	51%	0.509	34%	0.341	S	S	.	.			trans	-80.4	122.2	157.6	61.6	0	0	0	0	109	E50	E50-T272 HydrophobicContact CB-CG2 4.37Å; E50-T272 WeakPolarHBondContact O-CA 3.14Å
273	Y	83.2	Confident	85.8	Confident	7 Å²	7	71.4 Å²	71.4	3%	0.027	35%	0.352	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.1	114.7	179.8	-66.9	-90.7	0	0	0	109.7	S49 E50 V51 Y52 L268 K271 W275 P297 W300	S49-Y273 WeakPolarHBondContact OG-CD2 3.4Å; S49-Y273 WeakPolarHBondContact OG-CE2 3.41Å; E50-Y273 PolarHBondContact O-N 3.26Å; V51-Y273 CarbonylContact C-O 3.55Å; V51-Y273 WeakPolarHBondContact CA-O 3.42Å; Y52-Y273 PolarHBondContact N-O 3.47Å; L268-Y273 PolarHBondContact O-OH 2.98Å; K271-Y273 HydrophobicContact CB-CD2 4.5Å; K271-Y273 HydrophobicContact CB-CE2 4.01Å; K271-Y273 WeakPolarHBondContact O-CD2 3.34Å; K271-Y273 WeakPolarHBondContact O-CE2 3.13Å; Y273-W275 HydrophobicContact CD1-CH2 4.26Å; Y273-W275 AromaticContact CD1-CZ2 3.63Å; Y273-W275 HydrophobicContact CD1-CZ2 3.63Å; Y273-W275 HydrophobicContact CG-CZ2 4.29Å; Y273-P297 VanDerWaalsContact CD1-O 3.24Å; Y273-P297 WeakPolarHBondContact CD1-O 3.41Å; Y273-P297 HydrophobicContact CE1-CG 4.34Å; Y273-P297 WeakPolarHBondContact CE1-O 3.35Å; Y273-W300 HydrophobicContact CE2-CB 3.86Å
274	K	81.9	Confident	85.6	Confident	137 Å²	137	76.1 Å²	76.1	60%	0.596	37%	0.369	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-109.1	104.3	177	-63.9	-172.3	178.9	-175.4	0	109.8	Y52	Y52-K274 CarbonylContact O-C 3.59Å; Y52-K274 WeakPolarHBondContact O-CA 3.02Å
275	W	85.9	Confident	85.5	Confident	4 Å²	4	83.1 Å²	83.1	2%	0.015	40%	0.396	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.6	95.5	178.5	-56	122.1	0	0	0	109.9	Y52 D53 D54 Y273 R290 F293 P297 Y298	Y52-W275 PolarHBondContact O-N 3.05Å; D53-W275 WeakPolarHBondContact CA-O 3.3Å; D53-W275 HydrophobicContact CB-CB 4.27Å; D54-W275 PolarHBondContact N-O 2.82Å; D54-W275 VanDerWaalsContact N-O 3.09Å; Y273-W275 HydrophobicContact CD1-CH2 4.26Å; Y273-W275 AromaticContact CD1-CZ2 3.63Å; Y273-W275 HydrophobicContact CD1-CZ2 3.63Å; Y273-W275 HydrophobicContact CG-CZ2 4.29Å; W275-R290 VanDerWaalsContact CE3-NH2 3.27Å; W275-R290 VanDerWaalsContact CZ3-NH1 3.34Å; W275-F293 VanDerWaalsContact CH2-O 3.26Å; W275-F293 WeakPolarHBondContact CH2-O 3.24Å; W275-F293 HydrophobicContact CZ3-CB 4.17Å; W275-F293 WeakPolarHBondContact CZ3-O 3.21Å; W275-P297 VanDerWaalsContact CZ2-O 3.32Å; W275-P297 WeakPolarHBondContact CZ2-O 3.45Å; W275-Y298 AromaticContact CD1-CD2 3.51Å; W275-Y298 AromaticContact CD1-CE2 3.36Å; W275-Y298 HydrophobicContact CG-CD2 4.29Å; W275-Y298 HydrophobicContact CG-CE2 4.18Å; W275-Y298 AromaticContact NE1-CD2 3.39Å; W275-Y298 AromaticContact NE1-CE2 3.73Å; W275-Y298 AromaticContact NE1-CG 3.85Å; W275-Y298 PolarHBondContact NE1-O 3.26Å
276	Q	84.4	Confident	85.4	Confident	72 Å²	72	83.6 Å²	83.6	34%	0.336	40%	0.403	S	S	.	.			trans	-106.7	150	172.1	-67.6	174	-41.5	0	0	110.6	Y52 D54 I281 R290	Y52-Q276 HydrophobicContact CE1-CG 4.15Å; D54-Q276 WeakPolarHBondContact OD2-CA 3.04Å; Q276-I281 HydrophobicContact CB-CG1 4.47Å; Q276-R290 PolarHBondContact O-NE 2.78Å
277	G	82.1	Confident	85.4	Confident	8 Å²	8	81.9 Å²	81.9	8%	0.082	39%	0.394	C	S	.	.			trans	-60.5	142.1	170.3	0	0	0	0	0	111.5	D54 W279 N280	D54-G277 PolarHBondContact OD1-N 2.7Å; D54-G277 PolarHBondContact OD2-N 3.23Å; G277-W279 PolarHBondContact O-N 2.86Å; G277-W279 VanDerWaalsContact O-N 3.11Å; G277-N280 WeakPolarHBondContact O-CB 3.37Å; G277-N280 PolarHBondContact O-N 3.19Å
278	L	85.1	Confident	85.5	Confident	74 Å²	74	82 Å²	82	39%	0.387	40%	0.402	S	S	.	.	G	3₁₀ helix	trans	-57.9	-29.9	-178.7	-87.5	77.8	0	0	0	112.7	N280 I281 K287 R290 I291	L278-N280 VanDerWaalsContact C-N 3.33Å; L278-I281 PolarHBondContact O-N 3.27Å; L278-K287 WeakPolarHBondContact O-CE 3.5Å; L278-R290 HydrophobicContact CD1-CG 4.33Å; L278-I291 HydrophobicContact CD2-CD1 4.06Å; L278-I291 HydrophobicContact CD2-CG1 4.01Å
279	W	83.6	Confident	85.6	Confident	221 Å²	221	87.8 Å²	87.8	84%	0.837	43%	0.426	S	S	*	.	G	3₁₀ helix	trans	-73.3	-23.9	178.8	-59	110.1	0	0	0	113.2	G277 I281	G277-W279 PolarHBondContact O-N 2.86Å; G277-W279 VanDerWaalsContact O-N 3.11Å; W279-I281 VanDerWaalsContact C-N 3.27Å; W279-I281 PolarHBondContact O-N 2.81Å
280	N	84.7	Confident	85.8	Confident	98 Å²	98	88 Å²	88	52%	0.524	43%	0.425	S	S	.	.	G	3₁₀ helix	trans	-82.5	-5.6	177.8	-62.6	-21.6	0	0	0	112.3	D54 G277 L278	D54-N280 PolarHBondContact OD2-ND2 3.48Å; G277-N280 WeakPolarHBondContact O-CB 3.37Å; G277-N280 PolarHBondContact O-N 3.19Å; L278-N280 VanDerWaalsContact C-N 3.33Å
281	I	87.6	Confident	86.3	Confident	19 Å²	19	86.2 Å²	86.2	10%	0.097	42%	0.415	C	S	.	.			trans	-100.3	113.9	-179.5	-57.9	173.8	0	0	0	109.4	Q276 L278 W279 T283 K287 R290	Q276-I281 HydrophobicContact CB-CG1 4.47Å; L278-I281 PolarHBondContact O-N 3.27Å; W279-I281 VanDerWaalsContact C-N 3.27Å; W279-I281 PolarHBondContact O-N 2.81Å; I281-T283 PolarHBondContact O-N 3.44Å; I281-K287 HydrophobicContact CB-CG 4.13Å; I281-K287 HydrophobicContact CG2-CG 4.13Å; I281-K287 WeakPolarHBondContact O-CE 3.22Å; I281-R290 HydrophobicContact CD1-CB 3.53Å; I281-R290 HydrophobicContact CD1-CG 3.67Å
282	P	89.3	Confident	86.7	Confident	125 Å²	125	86.9 Å²	86.9	81%	0.812	43%	0.43	S	S	*	.			trans	-75.1	-25.1	-172.9	27	-33.5	0	0	0	113.5
283	T	92.3	Very high	87.1	Confident	79 Å²	79	85.7 Å²	85.7	49%	0.485	42%	0.418	S	S	.	.			trans	-101.7	140.4	-172.9	63.3	0	0	0	0	113.1	I281 K285 G286 K287	I281-T283 PolarHBondContact O-N 3.44Å; T283-K285 VanDerWaalsContact C-N 3.34Å; T283-K285 PolarHBondContact O-N 3.36Å; T283-G286 PolarHBondContact O-N 3.42Å; T283-G286 VanDerWaalsContact O-N 3.11Å; T283-G286 PolarHBondContact OG1-N 3.4Å; T283-G286 VanDerWaalsContact OG1-N 3.14Å; T283-K287 WeakPolarHBondContact O-CG 3.46Å; T283-K287 PolarHBondContact O-N 2.94Å
284	Y	91.3	Very high	87.2	Confident	193 Å²	193	86.7 Å²	86.7	76%	0.757	42%	0.422	S	S	*	.	H	α-helix	trans	-60	-41.2	174.3	-71.6	-72.2	0	0	0	112.7	G286 K287 M288	Y284-G286 VanDerWaalsContact C-N 3.29Å; Y284-G286 PolarHBondContact O-N 3.24Å; Y284-K287 PolarHBondContact O-N 2.06Å; Y284-M288 WeakPolarHBondContact O-CG 3.23Å; Y284-M288 PolarHBondContact O-N 2.77Å
285	K	90.3	Very high	87.4	Confident	184 Å²	184	87.7 Å²	87.7	80%	0.8	43%	0.427	S	S	*	.	H	α-helix	trans	-59	-41.6	173.6	-69	-174.8	178.9	-178.5	0	111.5	T283 K289	T283-K285 VanDerWaalsContact C-N 3.34Å; T283-K285 PolarHBondContact O-N 3.36Å; K285-K289 VanDerWaalsContact O-CB 3.28Å; K285-K289 WeakPolarHBondContact O-CB 3.39Å; K285-K289 PolarHBondContact O-N 2.72Å
286	G	88.9	Confident	87.4	Confident	19 Å²	19	88.5 Å²	88.5	20%	0.196	43%	0.432	C	S	.	.	H	α-helix	trans	-64	-42.1	175.1	0	0	0	0	0	112.7	T283 Y284 K289 R290	T283-G286 PolarHBondContact O-N 3.42Å; T283-G286 VanDerWaalsContact O-N 3.11Å; T283-G286 PolarHBondContact OG1-N 3.4Å; T283-G286 VanDerWaalsContact OG1-N 3.14Å; Y284-G286 VanDerWaalsContact C-N 3.29Å; Y284-G286 PolarHBondContact O-N 3.24Å; G286-K289 PolarHBondContact O-N 2.81Å; G286-R290 WeakPolarHBondContact O-CB 3.04Å; G286-R290 PolarHBondContact O-N 3.11Å
287	K	90.4	Very high	87.4	Confident	56 Å²	56	86.8 Å²	86.8	24%	0.243	43%	0.428	C	S	.	.	H	α-helix	trans	-62.7	-47.5	175.6	-69.1	-180	-175.1	-176.6	0	111.7	L278 I281 T283 Y284 K289 R290 I291	L278-K287 WeakPolarHBondContact O-CE 3.5Å; I281-K287 HydrophobicContact CB-CG 4.13Å; I281-K287 HydrophobicContact CG2-CG 4.13Å; I281-K287 WeakPolarHBondContact O-CE 3.22Å; T283-K287 WeakPolarHBondContact O-CG 3.46Å; T283-K287 PolarHBondContact O-N 2.94Å; Y284-K287 PolarHBondContact O-N 2.06Å; K287-K289 VanDerWaalsContact C-N 3.34Å; K287-K289 PolarHBondContact O-N 2.7Å; K287-R290 WeakPolarHBondContact O-CB 3.49Å; K287-R290 PolarHBondContact O-N 3.11Å; K287-I291 VanDerWaalsContact O-CG1 3.3Å; K287-I291 WeakPolarHBondContact O-CG1 3.42Å; K287-I291 PolarHBondContact O-N 2.61Å
288	M	89.4	Confident	87.5	Confident	138 Å²	138	90.1 Å²	90.1	68%	0.68	44%	0.438	S	S	*	.	H	α-helix	trans	-60.4	-44	175.6	-72.2	-175.7	70.3	0	0	111.8	Y284 R290 I291 A292	Y284-M288 WeakPolarHBondContact O-CG 3.23Å; Y284-M288 PolarHBondContact O-N 2.77Å; M288-R290 PolarHBondContact O-N 3.21Å; M288-I291 PolarHBondContact O-N 3.33Å; M288-A292 PolarHBondContact O-N 3.18Å
289	K	88.6	Confident	87.4	Confident	138 Å²	138	88.7 Å²	88.7	60%	0.6	43%	0.434	S	S	*	.	H	α-helix	trans	-57.5	-48.3	174	-174.7	176.1	179.5	-178.1	0	110.6	K285 G286 K287 I291 A292 F293	K285-K289 VanDerWaalsContact O-CB 3.28Å; K285-K289 WeakPolarHBondContact O-CB 3.39Å; K285-K289 PolarHBondContact O-N 2.72Å; G286-K289 PolarHBondContact O-N 2.81Å; K287-K289 VanDerWaalsContact C-N 3.34Å; K287-K289 PolarHBondContact O-N 2.7Å; K289-I291 VanDerWaalsContact C-N 3.32Å; K289-I291 PolarHBondContact O-N 2.91Å; K289-A292 PolarHBondContact O-N 3.19Å; K289-F293 HydrophobicContact CD-CE2 4.06Å; K289-F293 VanDerWaalsContact CE-CE2 3.42Å; K289-F293 HydrophobicContact CG-CD2 3.63Å; K289-F293 HydrophobicContact CG-CE2 3.45Å; K289-F293 VanDerWaalsContact CG-CE2 3.45Å; K289-F293 WeakPolarHBondContact O-CD2 3.33Å; K289-F293 PolarHBondContact O-N 3.33Å
290	R	87.9	Confident	87.5	Confident	20 Å²	20	78.8 Å²	78.8	8%	0.075	40%	0.397	C	S	.	.	H	α-helix	trans	-61.6	-36.4	178.8	178	61.4	-175.8	94.4	-7.7	113.2	W275 Q276 L278 I281 G286 K287 M288 Q294	W275-R290 VanDerWaalsContact CE3-NH2 3.27Å; W275-R290 VanDerWaalsContact CZ3-NH1 3.34Å; Q276-R290 PolarHBondContact O-NE 2.78Å; L278-R290 HydrophobicContact CD1-CG 4.33Å; I281-R290 HydrophobicContact CD1-CB 3.53Å; I281-R290 HydrophobicContact CD1-CG 3.67Å; G286-R290 WeakPolarHBondContact O-CB 3.04Å; G286-R290 PolarHBondContact O-N 3.11Å; K287-R290 WeakPolarHBondContact O-CB 3.49Å; K287-R290 PolarHBondContact O-N 3.11Å; M288-R290 PolarHBondContact O-N 3.21Å; R290-Q294 PolarHBondContact O-N 3.49Å
291	I	88	Confident	87.4	Confident	87 Å²	87	74.3 Å²	74.3	45%	0.446	37%	0.373	S	S	.	.	H	α-helix	trans	-68.6	-44.4	174	-67.7	165	0	0	0	110.4	L278 K287 M288 K289 F293 Q294	L278-I291 HydrophobicContact CD2-CD1 4.06Å; L278-I291 HydrophobicContact CD2-CG1 4.01Å; K287-I291 VanDerWaalsContact O-CG1 3.3Å; K287-I291 WeakPolarHBondContact O-CG1 3.42Å; K287-I291 PolarHBondContact O-N 2.61Å; M288-I291 PolarHBondContact O-N 3.33Å; K289-I291 VanDerWaalsContact C-N 3.32Å; K289-I291 PolarHBondContact O-N 2.91Å; I291-F293 VanDerWaalsContact C-N 3.34Å; I291-F293 PolarHBondContact O-N 3.22Å; I291-Q294 WeakPolarHBondContact O-CB 3.46Å; I291-Q294 PolarHBondContact O-N 3.44Å
292	A	87.4	Confident	87.2	Confident	63 Å²	63	79 Å²	79	52%	0.521	39%	0.39	S	S	.	.	H	α-helix	trans	-62.2	-42	175.8	0	0	0	0	0	111.8	M288 K289 Q294 F295	M288-A292 PolarHBondContact O-N 3.18Å; K289-A292 PolarHBondContact O-N 3.19Å; A292-Q294 PolarHBondContact O-N 3.45Å; A292-Q294 VanDerWaalsContact O-N 3.13Å; A292-F295 PolarHBondContact O-N 3.38Å
293	F	85.9	Confident	87	Confident	58 Å²	58	73.7 Å²	73.7	25%	0.254	35%	0.354	S	S	.	.	G	3₁₀ helix	trans	-66	-10.5	174.1	-80.9	-71.8	0	0	0	113.5	K271 W275 K289 I291 F295 T296	K271-F293 HydrophobicContact CD-CE1 4.41Å; W275-F293 VanDerWaalsContact CH2-O 3.26Å; W275-F293 WeakPolarHBondContact CH2-O 3.24Å; W275-F293 HydrophobicContact CZ3-CB 4.17Å; W275-F293 WeakPolarHBondContact CZ3-O 3.21Å; K289-F293 HydrophobicContact CD-CE2 4.06Å; K289-F293 VanDerWaalsContact CE-CE2 3.42Å; K289-F293 HydrophobicContact CG-CD2 3.63Å; K289-F293 HydrophobicContact CG-CE2 3.45Å; K289-F293 VanDerWaalsContact CG-CE2 3.45Å; K289-F293 WeakPolarHBondContact O-CD2 3.33Å; K289-F293 PolarHBondContact O-N 3.33Å; I291-F293 VanDerWaalsContact C-N 3.34Å; I291-F293 PolarHBondContact O-N 3.22Å; F293-F295 PolarHBondContact O-N 3.44Å; F293-T296 HydrophobicContact CD1-CG2 3.76Å; F293-T296 HydrophobicContact CE1-CG2 4.36Å; F293-T296 WeakPolarHBondContact O-CB 3.42Å; F293-T296 PolarHBondContact O-N 2.95Å; F293-T296 PolarHBondContact O-OG1 2.89Å
294	Q	85.6	Confident	86.7	Confident	27 Å²	27	73.5 Å²	73.5	13%	0.126	35%	0.347	C	S	.	.	G	3₁₀ helix	trans	-58.2	-30.3	173.5	-169.1	65.5	20.9	0	0	112.6	R119 P120 R290 I291 A292 T296	R119-Q294 VanDerWaalsContact NH1-CD 3.27Å; P120-Q294 WeakPolarHBondContact CA-O 3.36Å; P120-Q294 HydrophobicContact CB-CG 4.49Å; P120-Q294 PolarHBondContact O-NE2 2.88Å; R290-Q294 PolarHBondContact O-N 3.49Å; I291-Q294 WeakPolarHBondContact O-CB 3.46Å; I291-Q294 PolarHBondContact O-N 3.44Å; A292-Q294 PolarHBondContact O-N 3.45Å; A292-Q294 VanDerWaalsContact O-N 3.13Å; Q294-T296 PolarHBondContact O-N 3.35Å
295	F	86.4	Confident	86.5	Confident	158 Å²	158	64.4 Å²	64.4	69%	0.693	31%	0.312	S	S	*	.	G	3₁₀ helix	trans	-85.8	4	178.5	-59.5	-82	0	0	0	113	P120 A292 F293	P120-F295 HydrophobicContact CB-CD1 4.02Å; P120-F295 HydrophobicContact CB-CE1 4.22Å; A292-F295 PolarHBondContact O-N 3.38Å; F293-F295 PolarHBondContact O-N 3.44Å
296	T	85.3	Confident	86.4	Confident	21 Å²	21	61.2 Å²	61.2	13%	0.129	30%	0.298	C	S	.	.	S	Bend	trans	-96.9	152	170.9	68.5	0	0	0	0	110.2	R119 F293 Q294	R119-T296 WeakPolarHBondContact CB-O 3.43Å; F293-T296 HydrophobicContact CD1-CG2 3.76Å; F293-T296 HydrophobicContact CE1-CG2 4.36Å; F293-T296 WeakPolarHBondContact O-CB 3.42Å; F293-T296 PolarHBondContact O-N 2.95Å; F293-T296 PolarHBondContact O-OG1 2.89Å; Q294-T296 PolarHBondContact O-N 3.35Å
297	P	85	Confident	86.3	Confident	36 Å²	36	62.7 Å²	62.7	23%	0.234	30%	0.304	C	S	.	.			trans	-64.7	146.3	-175.5	24.9	-34.1	0	0	0	111.4	Y273 W275 S299 W300	Y273-P297 VanDerWaalsContact CD1-O 3.24Å; Y273-P297 WeakPolarHBondContact CD1-O 3.41Å; Y273-P297 HydrophobicContact CE1-CG 4.34Å; Y273-P297 WeakPolarHBondContact CE1-O 3.35Å; W275-P297 VanDerWaalsContact CZ2-O 3.32Å; W275-P297 WeakPolarHBondContact CZ2-O 3.45Å; P297-S299 VanDerWaalsContact C-N 3.33Å; P297-S299 PolarHBondContact O-N 3.48Å; P297-W300 HydrophobicContact CB-CE3 4.05Å; P297-W300 HydrophobicContact CB-CZ3 4.34Å; P297-W300 HydrophobicContact CG-CE3 3.34Å; P297-W300 HydrophobicContact CG-CZ3 3.67Å
298	Y	83.8	Confident	86.2	Confident	79 Å²	79	61.8 Å²	61.8	31%	0.31	31%	0.307	S	S	.	.	S	Bend	trans	-57.2	-45.7	-179.8	177.7	-95.3	0	0	0	112.7	V51 D53 W275	V51-Y298 HydrophobicContact CG1-CE1 3.98Å; V51-Y298 HydrophobicContact CG1-CE2 4.45Å; D53-Y298 VanDerWaalsContact OD2-CE2 3.3Å; D53-Y298 WeakPolarHBondContact OD2-CE2 3.48Å; D53-Y298 PolarHBondContact OD2-OH 3.14Å; W275-Y298 AromaticContact CD1-CD2 3.51Å; W275-Y298 AromaticContact CD1-CE2 3.36Å; W275-Y298 HydrophobicContact CG-CD2 4.29Å; W275-Y298 HydrophobicContact CG-CE2 4.18Å; W275-Y298 AromaticContact NE1-CD2 3.39Å; W275-Y298 AromaticContact NE1-CE2 3.73Å; W275-Y298 AromaticContact NE1-CG 3.85Å; W275-Y298 PolarHBondContact NE1-O 3.26Å
299	S	84.3	Confident	86.1	Confident	43 Å²	43	58.3 Å²	58.3	30%	0.301	30%	0.296	S	S	.	.	S	Bend	trans	-138.1	155.3	170.9	64.9	0	0	0	0	107.6	P297	P297-S299 VanDerWaalsContact C-N 3.33Å; P297-S299 PolarHBondContact O-N 3.48Å
300	W	84.3	Confident	86.1	Confident	14 Å²	14	54 Å²	54	5%	0.053	28%	0.283	C	S	.	.			trans	-107.6	131	174.6	-165.7	-99.7	0	0	0	110.7	E48 S49 L265 L268 Y273 P297	E48-W300 WeakPolarHBondContact CA-O 3.31Å; S49-W300 PolarHBondContact N-O 3.26Å; S49-W300 PolarHBondContact OG-N 3.25Å; S49-W300 PolarHBondContact OG-O 2.97Å; L265-W300 HydrophobicContact CB-CZ2 4.06Å; L265-W300 HydrophobicContact CD2-CH2 3.38Å; L265-W300 HydrophobicContact CD2-CZ2 3.19Å; L265-W300 HydrophobicContact CG-CZ2 4.15Å; L268-W300 HydrophobicContact CB-CD2 3.84Å; L268-W300 HydrophobicContact CB-CE3 4.08Å; L268-W300 HydrophobicContact CB-CG 4.28Å; L268-W300 HydrophobicContact CB-CH2 4.47Å; L268-W300 HydrophobicContact CB-CZ2 4.32Å; L268-W300 HydrophobicContact CB-CZ3 4.37Å; L268-W300 HydrophobicContact CD1-CE3 4.1Å; L268-W300 HydrophobicContact CD1-CH2 3.62Å; L268-W300 HydrophobicContact CD1-CZ2 4.18Å; L268-W300 HydrophobicContact CD1-CZ3 3.59Å; Y273-W300 HydrophobicContact CE2-CB 3.86Å; P297-W300 HydrophobicContact CB-CE3 4.05Å; P297-W300 HydrophobicContact CB-CZ3 4.34Å; P297-W300 HydrophobicContact CG-CE3 3.34Å; P297-W300 HydrophobicContact CG-CZ3 3.67Å
301	V	83.1	Confident	86.1	Confident	4 Å²	4	55.9 Å²	55.9	2%	0.024	29%	0.294	C	S	.	.	B	Isolated β-bridge	trans	-117.9	122	174.9	-172.2	0	0	0	0	108.1	E48 R212	E48-V301 HydrophobicContact CG-CG1 4.24Å; E48-V301 HydrophobicContact CG-CG2 3.92Å; R212-V301 PolarHBondContact NH1-O 2.86Å
302	R	82.9	Confident	86.2	Confident	117 Å²	117	58 Å²	58	44%	0.442	30%	0.297	S	S	.	.			trans	-76.3	129.8	170.1	-67.8	-176.1	176.5	168.4	2.3	109.3	T47 S269	T47-R302 PolarHBondContact O-N 3.44Å; T47-R302 VanDerWaalsContact O-N 3.1Å; S269-R302 PolarHBondContact OG-NE 3.48Å; S269-R302 PolarHBondContact OG-NH2 3.43Å
303	F	85.9	Confident	86.3	Confident	13 Å²	13	57.2 Å²	57.2	6%	0.057	28%	0.28	C	S	.	.			trans	-84.8	121.6	177.9	-64.6	-13.1	0	0	0	110.1	I211 R212 W305 M362 R363 Y366	I211-F303 WeakPolarHBondContact O-CD2 3.47Å; R212-F303 HydrophobicContact CB-CD2 3.75Å; R212-F303 HydrophobicContact CB-CE2 4.2Å; R212-F303 HydrophobicContact CB-CG 4.29Å; R212-F303 HydrophobicContact CG-CD2 4.09Å; R212-F303 HydrophobicContact CG-CE2 4.02Å; F303-W305 HydrophobicContact CB-CZ2 4.34Å; F303-W305 AromaticContact CD2-CE2 4Å; F303-W305 AromaticContact CD2-CZ2 3.6Å; F303-W305 HydrophobicContact CD2-CZ2 3.6Å; F303-W305 AromaticContact CD2-NE1 3.93Å; F303-W305 HydrophobicContact CE2-CZ2 4.18Å; F303-W305 HydrophobicContact CG-CZ2 4.2Å; F303-M362 HydrophobicContact CE2-CB 4.34Å; F303-R363 HydrophobicContact CZ-CB 4.3Å; F303-Y366 HydrophobicContact CB-CD2 3.85Å; F303-Y366 HydrophobicContact CB-CE2 3.83Å; F303-Y366 HydrophobicContact CD1-CD1 4.07Å; F303-Y366 AromaticContact CD1-CD2 3.83Å; F303-Y366 HydrophobicContact CD1-CD2 3.83Å; F303-Y366 HydrophobicContact CD1-CE1 4.38Å; F303-Y366 HydrophobicContact CD1-CE2 4.18Å; F303-Y366 AromaticContact CD1-CG 3.78Å; F303-Y366 HydrophobicContact CD1-CG 3.78Å; F303-Y366 HydrophobicContact CE1-CD1 4.32Å; F303-Y366 HydrophobicContact CE1-CG 4.1Å; F303-Y366 AromaticContact CG-CD2 3.84Å; F303-Y366 HydrophobicContact CG-CD2 3.84Å; F303-Y366 HydrophobicContact CG-CE2 4.23Å; F303-Y366 HydrophobicContact CG-CG 4.19Å
304	E	86.8	Confident	86.6	Confident	75 Å²	75	56.4 Å²	56.4	35%	0.35	28%	0.276	S	S	.	.			trans	-112.3	80.8	172.7	-67	-173.5	-176.5	0	0	110	T47 K306 R313 Y366	T47-E304 HydrophobicContact CG2-CG 4.14Å; T47-E304 VanDerWaalsContact CG2-OE1 3.27Å; T47-E304 WeakPolarHBondContact CG2-OE1 3.43Å; E304-K306 VanDerWaalsContact C-N 3.29Å; E304-K306 HydrophobicContact CB-CG 4.47Å; E304-K306 PolarHBondContact O-N 3.39Å; E304-K306 WeakPolarHBondContact OE2-CE 3.4Å; E304-K306 IonicContact OE2-NZ 2.72Å; E304-K306 PolarHBondContact OE2-NZ 2.84Å; E304-R313 PolarHBondContact O-NH1 3.35Å; E304-Y366 VanDerWaalsContact N-CE2 3.32Å; E304-Y366 PolarHBondContact N-OH 3.19Å
305	W	85.9	Confident	87	Confident	3 Å²	3	59.9 Å²	59.9	1%	0.011	30%	0.295	C	S	.	.			trans	-59.3	-38.3	-174.7	-64.7	97.9	0	0	0	113	M216 F303 R313 V317 I320 M362 I365 Y366 M369	M216-W305 HydrophobicContact SD-CB 4.4Å; M216-W305 VanDerWaalsContact SD-CD1 3.54Å; M216-W305 HydrophobicContact SD-CD2 3.78Å; M216-W305 HydrophobicContact SD-CE3 4.43Å; M216-W305 HydrophobicContact SD-CG 3.66Å; F303-W305 HydrophobicContact CB-CZ2 4.34Å; F303-W305 AromaticContact CD2-CE2 4Å; F303-W305 AromaticContact CD2-CZ2 3.6Å; F303-W305 HydrophobicContact CD2-CZ2 3.6Å; F303-W305 AromaticContact CD2-NE1 3.93Å; F303-W305 HydrophobicContact CE2-CZ2 4.18Å; F303-W305 HydrophobicContact CG-CZ2 4.2Å; W305-R313 PolarHBondContact O-NH1 2.99Å; W305-R313 VanDerWaalsContact O-NH1 3.16Å; W305-V317 HydrophobicContact CB-CG2 4.13Å; W305-V317 HydrophobicContact CE3-CG2 4.02Å; W305-I320 HydrophobicContact CE3-CD1 3.96Å; W305-I320 HydrophobicContact CH2-CD1 3.86Å; W305-I320 HydrophobicContact CZ3-CD1 3.27Å; W305-M362 HydrophobicContact CH2-CE 3.63Å; W305-M362 HydrophobicContact CZ2-CE 3.44Å; W305-M362 VanDerWaalsContact CZ2-CE 3.44Å; W305-I365 HydrophobicContact CH2-CG2 4.38Å; W305-I365 HydrophobicContact CZ3-CG2 4.22Å; W305-Y366 HydrophobicContact CD2-CD2 4.46Å; W305-Y366 HydrophobicContact CH2-CD2 4.24Å; W305-Y366 HydrophobicContact CZ2-CD2 4.17Å; W305-Y366 HydrophobicContact CZ3-CD2 4.48Å; W305-M369 HydrophobicContact CD2-CE 4.4Å; W305-M369 HydrophobicContact CE3-CE 3.23Å; W305-M369 HydrophobicContact CE3-SD 4.43Å; W305-M369 HydrophobicContact CH2-CE 4.27Å; W305-M369 HydrophobicContact CZ3-CE 3.12Å; W305-M369 HydrophobicContact CZ3-SD 4.18Å
306	K	87.4	Confident	87.2	Confident	117 Å²	117	53.8 Å²	53.8	51%	0.509	27%	0.274	S	S	.	.			trans	45.6	56.6	-179.3	-65.6	173.3	179.9	158	0	111.9	E304 A308 S309	E304-K306 VanDerWaalsContact C-N 3.29Å; E304-K306 HydrophobicContact CB-CG 4.47Å; E304-K306 PolarHBondContact O-N 3.39Å; E304-K306 WeakPolarHBondContact OE2-CE 3.4Å; E304-K306 IonicContact OE2-NZ 2.72Å; E304-K306 PolarHBondContact OE2-NZ 2.84Å; K306-A308 VanDerWaalsContact C-N 3.26Å; K306-A308 PolarHBondContact O-N 3.43Å; K306-A308 VanDerWaalsContact O-N 3.16Å; K306-S309 VanDerWaalsContact O-CB 3.28Å; K306-S309 WeakPolarHBondContact O-CB 3.37Å; K306-S309 PolarHBondContact O-N 2.98Å; K306-S309 PolarHBondContact O-OG 3.12Å
307	P	87.3	Confident	87.7	Confident	49 Å²	49	53.1 Å²	53.1	32%	0.318	27%	0.269	S	S	.	.	G	3₁₀ helix	trans	-55.8	-38.4	-171.8	19.3	-31.4	0	0	0	113	S309 W314 V317	P307-S309 VanDerWaalsContact C-N 3.25Å; P307-S309 PolarHBondContact O-N 3.01Å; P307-W314 HydrophobicContact CB-CE3 3.97Å; P307-W314 HydrophobicContact CB-CZ3 4.42Å; P307-W314 WeakPolarHBondContact O-CA 3.43Å; P307-W314 WeakPolarHBondContact O-CB 3.4Å; P307-W314 PolarHBondContact O-N 3.39Å; P307-V317 HydrophobicContact CB-CB 4.26Å; P307-V317 HydrophobicContact CB-CG1 4.37Å; P307-V317 HydrophobicContact CB-CG2 4.1Å
308	A	87.9	Confident	88.1	Confident	37 Å²	37	53.4 Å²	53.4	31%	0.306	27%	0.272	S	S	.	.	G	3₁₀ helix	trans	-79.1	3.6	-178.9	0	0	0	0	0	114.8	K306 W426 R430	K306-A308 VanDerWaalsContact C-N 3.26Å; K306-A308 PolarHBondContact O-N 3.43Å; K306-A308 VanDerWaalsContact O-N 3.16Å; A308-W426 HydrophobicContact CB-CH2 4.17Å; A308-R430 VanDerWaalsContact O-CZ 3.28Å; A308-R430 PolarHBondContact O-NE 3.4Å; A308-R430 PolarHBondContact O-NH2 3.27Å
309	S	87.3	Confident	88.7	Confident	66 Å²	66	51.1 Å²	51.1	46%	0.462	27%	0.272	S	S	.	.	G	3₁₀ helix	trans	-80.9	-36.4	-175.8	61.7	0	0	0	0	113.5	K306 P307 R313	K306-S309 VanDerWaalsContact O-CB 3.28Å; K306-S309 WeakPolarHBondContact O-CB 3.37Å; K306-S309 PolarHBondContact O-N 2.98Å; K306-S309 PolarHBondContact O-OG 3.12Å; P307-S309 VanDerWaalsContact C-N 3.25Å; P307-S309 PolarHBondContact O-N 3.01Å; S309-R313 WeakPolarHBondContact OG-CD 3.41Å
310	S	88.9	Confident	89.2	Confident	46 Å²	46	49.9 Å²	49.9	32%	0.322	26%	0.262	S	S	.	.			trans	-148.7	153.6	175.8	70.8	0	0	0	0	110.6	R312 R313 W314	S310-R312 PolarHBondContact O-N 3.36Å; S310-R313 PolarHBondContact O-N 2.92Å; S310-R313 VanDerWaalsContact O-N 3.12Å; S310-R313 PolarHBondContact OG-N 2.86Å; S310-W314 PolarHBondContact O-N 2.93Å
311	L	89.1	Confident	89.8	Confident	60 Å²	60	50 Å²	50	31%	0.314	26%	0.263	S	S	.	.	H	α-helix	trans	-58	-37.2	177.5	-177.9	63.1	0	0	0	111.5	R313 W314 L315 T427 F431 F432	L311-R313 PolarHBondContact O-N 3.46Å; L311-W314 PolarHBondContact O-N 3.39Å; L311-L315 HydrophobicContact CD1-CD1 4.23Å; L311-L315 HydrophobicContact CD1-CG 4.13Å; L311-L315 HydrophobicContact CG-CD1 4.02Å; L311-L315 HydrophobicContact CG-CG 4.33Å; L311-L315 WeakPolarHBondContact O-CB 3.19Å; L311-L315 WeakPolarHBondContact O-CG 3.21Å; L311-L315 PolarHBondContact O-N 2.86Å; L311-T427 HydrophobicContact CD1-CG2 3.9Å; L311-F431 HydrophobicContact CB-CD1 4.27Å; L311-F431 HydrophobicContact CB-CG 4.24Å; L311-F431 HydrophobicContact CD1-CB 4.41Å; L311-F431 HydrophobicContact CD1-CD2 3.93Å; L311-F431 HydrophobicContact CD1-CE2 4.47Å; L311-F431 HydrophobicContact CD1-CG 4.19Å; L311-F432 HydrophobicContact CD2-CE2 4.27Å; L311-F432 HydrophobicContact CD2-CZ 3.98Å
312	R	88.7	Confident	90.4	Very high	133 Å²	133	55.5 Å²	55.5	50%	0.502	29%	0.292	S	S	.	.	H	α-helix	trans	-59.6	-46.3	175.8	-177.9	179.9	174.2	-159	-5.1	112	S310 A316	S310-R312 PolarHBondContact O-N 3.36Å; R312-A316 VanDerWaalsContact O-CB 3.26Å; R312-A316 WeakPolarHBondContact O-CB 3.49Å; R312-A316 PolarHBondContact O-N 2.9Å
313	R	90.4	Very high	91	Very high	45 Å²	45	52.6 Å²	52.6	17%	0.17	29%	0.287	C	S	.	.	H	α-helix	trans	-69	-38.3	178.6	-78.7	176.7	176.1	-102.1	-2.1	112	E304 W305 S309 S310 L311 A316 V317 D370	E304-R313 PolarHBondContact O-NH1 3.35Å; W305-R313 PolarHBondContact O-NH1 2.99Å; W305-R313 VanDerWaalsContact O-NH1 3.16Å; S309-R313 WeakPolarHBondContact OG-CD 3.41Å; S310-R313 PolarHBondContact O-N 2.92Å; S310-R313 VanDerWaalsContact O-N 3.12Å; S310-R313 PolarHBondContact OG-N 2.86Å; L311-R313 PolarHBondContact O-N 3.46Å; R313-A316 PolarHBondContact O-N 3.17Å; R313-V317 WeakPolarHBondContact O-CG2 3.23Å; R313-V317 PolarHBondContact O-N 3.36Å; R313-D370 IonicContact CZ-OD1 3.39Å; R313-D370 IonicContact NH1-OD1 3.9Å; R313-D370 PolarHBondContact NH1-OD1 3.39Å; R313-D370 IonicContact NH2-OD1 2.66Å; R313-D370 PolarHBondContact NH2-OD1 3.36Å
314	W	92.8	Very high	91.5	Very high	41 Å²	41	53.1 Å²	53.1	16%	0.155	29%	0.29	C	S	.	.	H	α-helix	trans	-58.1	-55.8	173.7	173.9	-116.9	0	0	0	111.8	P307 S310 L311 A316 V317 C318 V423 W426 T427 F431	P307-W314 HydrophobicContact CB-CE3 3.97Å; P307-W314 HydrophobicContact CB-CZ3 4.42Å; P307-W314 WeakPolarHBondContact O-CA 3.43Å; P307-W314 WeakPolarHBondContact O-CB 3.4Å; P307-W314 PolarHBondContact O-N 3.39Å; S310-W314 PolarHBondContact O-N 2.93Å; L311-W314 PolarHBondContact O-N 3.39Å; W314-A316 VanDerWaalsContact C-N 3.28Å; W314-A316 PolarHBondContact O-N 2.89Å; W314-V317 PolarHBondContact O-N 3.02Å; W314-C318 PolarHBondContact O-N 2.87Å; W314-C318 PolarHBondContact O-SG 3.16Å; W314-C318 VanDerWaalsContact O-SG 3.36Å; W314-V423 HydrophobicContact CZ2-CG1 4.14Å; W314-W426 HydrophobicContact CD2-CH2 4.47Å; W314-W426 AromaticContact CD2-CZ3 3.66Å; W314-W426 HydrophobicContact CD2-CZ3 3.66Å; W314-W426 AromaticContact CE2-CE3 3.98Å; W314-W426 AromaticContact CE2-CZ3 3.57Å; W314-W426 HydrophobicContact CE3-CH2 4.07Å; W314-W426 AromaticContact CE3-CZ3 3.64Å; W314-W426 HydrophobicContact CE3-CZ3 3.64Å; W314-W426 HydrophobicContact CG-CZ3 4.46Å; W314-W426 AromaticContact CH2-CE3 3.85Å; W314-W426 HydrophobicContact CH2-CE3 3.85Å; W314-W426 HydrophobicContact CH2-CH2 4.21Å; W314-W426 AromaticContact CH2-CZ3 3.5Å; W314-W426 HydrophobicContact CH2-CZ3 3.5Å; W314-W426 VanDerWaalsContact CH2-CZ3 3.5Å; W314-W426 AromaticContact CZ2-CE3 3.62Å; W314-W426 HydrophobicContact CZ2-CE3 3.62Å; W314-W426 AromaticContact CZ2-CZ3 3.49Å; W314-W426 HydrophobicContact CZ2-CZ3 3.49Å; W314-W426 VanDerWaalsContact CZ2-CZ3 3.49Å; W314-W426 HydrophobicContact CZ3-CE3 4.38Å; W314-W426 AromaticContact CZ3-CH2 3.94Å; W314-W426 HydrophobicContact CZ3-CH2 3.94Å; W314-W426 AromaticContact CZ3-CZ3 3.57Å; W314-W426 HydrophobicContact CZ3-CZ3 3.57Å; W314-T427 PolarHBondContact NE1-OG1 2.93Å; W314-F431 HydrophobicContact CB-CE2 3.61Å; W314-F431 HydrophobicContact CB-CZ 3.61Å; W314-F431 AromaticContact CD1-CE2 3.81Å; W314-F431 HydrophobicContact CD2-CE2 4.28Å; W314-F431 AromaticContact CG-CE2 3.61Å; W314-F431 HydrophobicContact CG-CE2 3.61Å; W314-F431 HydrophobicContact CG-CZ 4.1Å
315	L	92.5	Very high	92	Very high	101 Å²	101	50 Å²	50	53%	0.529	28%	0.275	S	S	.	.	H	α-helix	trans	-62.4	-36.5	-180	-67.1	176.6	0	0	0	112.1	L311 C318 G319	L311-L315 HydrophobicContact CD1-CD1 4.23Å; L311-L315 HydrophobicContact CD1-CG 4.13Å; L311-L315 HydrophobicContact CG-CD1 4.02Å; L311-L315 HydrophobicContact CG-CG 4.33Å; L311-L315 WeakPolarHBondContact O-CB 3.19Å; L311-L315 WeakPolarHBondContact O-CG 3.21Å; L311-L315 PolarHBondContact O-N 2.86Å; L315-C318 PolarHBondContact O-N 2.77Å; L315-G319 PolarHBondContact O-N 3.25Å
316	A	92.3	Very high	92.6	Very high	30 Å²	30	51.9 Å²	51.9	25%	0.248	29%	0.285	C	S	.	.	H	α-helix	trans	-64.6	-44.3	175.8	0	0	0	0	0	112.1	R312 R313 W314 G319 I320 M369	R312-A316 VanDerWaalsContact O-CB 3.26Å; R312-A316 WeakPolarHBondContact O-CB 3.49Å; R312-A316 PolarHBondContact O-N 2.9Å; R313-A316 PolarHBondContact O-N 3.17Å; W314-A316 VanDerWaalsContact C-N 3.28Å; W314-A316 PolarHBondContact O-N 2.89Å; A316-G319 PolarHBondContact O-N 2.66Å; A316-I320 VanDerWaalsContact O-CG1 3.25Å; A316-I320 WeakPolarHBondContact O-CG1 3.25Å; A316-I320 PolarHBondContact O-N 3.21Å; A316-M369 HydrophobicContact CB-CG 4.44Å; A316-M369 HydrophobicContact CB-SD 3.41Å; A316-M369 WeakPolarHBondContact CB-SD 3.38Å
317	V	94.2	Very high	93	Very high	7 Å²	7	46.8 Å²	46.8	4%	0.042	27%	0.265	C	S	.	.	H	α-helix	trans	-63.8	-42.6	175.9	171.2	0	0	0	0	111.1	M216 W305 P307 R313 W314 G319 I320 I321	M216-V317 HydrophobicContact CE-CG1 4.25Å; M216-V317 HydrophobicContact CG-CG1 4.26Å; M216-V317 HydrophobicContact SD-CG1 4.17Å; W305-V317 HydrophobicContact CB-CG2 4.13Å; W305-V317 HydrophobicContact CE3-CG2 4.02Å; P307-V317 HydrophobicContact CB-CB 4.26Å; P307-V317 HydrophobicContact CB-CG1 4.37Å; P307-V317 HydrophobicContact CB-CG2 4.1Å; R313-V317 WeakPolarHBondContact O-CG2 3.23Å; R313-V317 PolarHBondContact O-N 3.36Å; W314-V317 PolarHBondContact O-N 3.02Å; V317-G319 VanDerWaalsContact C-N 3.31Å; V317-G319 PolarHBondContact O-N 2.98Å; V317-I320 PolarHBondContact O-N 3.33Å; V317-I321 HydrophobicContact CG1-CD1 4.02Å; V317-I321 WeakPolarHBondContact O-CG1 3.24Å; V317-I321 PolarHBondContact O-N 2.92Å
318	C	95.1	Very high	93.4	Very high	42 Å²	42	45.3 Å²	45.3	28%	0.284	25%	0.254	S	S	.	.	H	α-helix	trans	-59.2	-42.7	172.8	-65.2	0	0	0	0	112	W314 L315 I321 L322	W314-C318 PolarHBondContact O-N 2.87Å; W314-C318 PolarHBondContact O-SG 3.16Å; W314-C318 VanDerWaalsContact O-SG 3.36Å; L315-C318 PolarHBondContact O-N 2.77Å; C318-I321 PolarHBondContact O-N 2.99Å; C318-L322 WeakPolarHBondContact O-CB 3.5Å; C318-L322 PolarHBondContact O-N 3.16Å
319	G	95	Very high	93.8	Very high	31 Å²	31	44.8 Å²	44.8	32%	0.32	25%	0.246	S	C	.	.	H	α-helix	trans	-64.1	-39.7	176.8	0	0	0	0	0	113	L315 A316 V317 L322 V323	L315-G319 PolarHBondContact O-N 3.25Å; A316-G319 PolarHBondContact O-N 2.66Å; V317-G319 VanDerWaalsContact C-N 3.31Å; V317-G319 PolarHBondContact O-N 2.98Å; G319-L322 PolarHBondContact O-N 2.62Å; G319-V323 WeakPolarHBondContact O-CG2 3.19Å; G319-V323 PolarHBondContact O-N 3.29Å
320	I	95.2	Very high	94.2	Very high	16 Å²	16	41.8 Å²	41.8	8%	0.082	23%	0.225	C	C	.	.	H	α-helix	trans	-62.4	-48.2	174.7	-67.7	162.3	0	0	0	110.3	M216 W305 A316 V317 L322 V323 F324 M362 I365	M216-I320 HydrophobicContact CE-CB 4.36Å; M216-I320 HydrophobicContact CE-CG2 3.78Å; W305-I320 HydrophobicContact CE3-CD1 3.96Å; W305-I320 HydrophobicContact CH2-CD1 3.86Å; W305-I320 HydrophobicContact CZ3-CD1 3.27Å; A316-I320 VanDerWaalsContact O-CG1 3.25Å; A316-I320 WeakPolarHBondContact O-CG1 3.25Å; A316-I320 PolarHBondContact O-N 3.21Å; V317-I320 PolarHBondContact O-N 3.33Å; I320-L322 VanDerWaalsContact C-N 3.31Å; I320-L322 PolarHBondContact O-N 2.94Å; I320-V323 PolarHBondContact O-N 3.02Å; I320-F324 WeakPolarHBondContact O-CB 3.41Å; I320-F324 PolarHBondContact O-N 3.4Å; I320-M362 HydrophobicContact CG2-CE 3.84Å; I320-M362 HydrophobicContact CG2-SD 3.79Å; I320-I365 HydrophobicContact CD1-CG2 3.62Å; I320-I365 HydrophobicContact CG1-CG2 4.1Å
321	I	96.2	Very high	94.5	Very high	17 Å²	17	40.3 Å²	40.3	9%	0.087	21%	0.214	C	C	.	.	H	α-helix	trans	-58.1	-46.5	177.4	-69.2	167.4	0	0	0	110	I219 I220 M223 V317 C318 F324 L325	I219-I321 HydrophobicContact CG2-CD1 4.03Å; I220-I321 HydrophobicContact CD1-CG1 4.31Å; I220-I321 HydrophobicContact CG1-CB 4.41Å; I220-I321 HydrophobicContact CG1-CG1 4.07Å; I220-I321 HydrophobicContact CG1-CG2 4.07Å; M223-I321 HydrophobicContact CE-CG2 4.5Å; M223-I321 HydrophobicContact SD-CG2 3.86Å; V317-I321 HydrophobicContact CG1-CD1 4.02Å; V317-I321 WeakPolarHBondContact O-CG1 3.24Å; V317-I321 PolarHBondContact O-N 2.92Å; C318-I321 PolarHBondContact O-N 2.99Å; I321-F324 PolarHBondContact O-N 3.4Å; I321-L325 HydrophobicContact CG2-CD1 3.79Å; I321-L325 HydrophobicContact CG2-CG 4.34Å; I321-L325 VanDerWaalsContact O-CG 3.31Å; I321-L325 WeakPolarHBondContact O-CG 3.17Å; I321-L325 PolarHBondContact O-N 3.37Å
322	L	96.4	Very high	94.7	Very high	119 Å²	119	39.8 Å²	39.8	62%	0.623	21%	0.209	S	C	*	.	H	α-helix	trans	-59.8	-49.1	178.5	-179.8	67.7	0	0	0	112.4	C318 G319 I320 F324 L325 L326	C318-L322 WeakPolarHBondContact O-CB 3.5Å; C318-L322 PolarHBondContact O-N 3.16Å; G319-L322 PolarHBondContact O-N 2.62Å; I320-L322 VanDerWaalsContact C-N 3.31Å; I320-L322 PolarHBondContact O-N 2.94Å; L322-F324 VanDerWaalsContact C-N 3.28Å; L322-F324 PolarHBondContact O-N 3.4Å; L322-L325 PolarHBondContact O-N 2.85Å; L322-L326 VanDerWaalsContact O-CB 3.27Å; L322-L326 WeakPolarHBondContact O-CB 3.39Å; L322-L326 PolarHBondContact O-N 3.4Å
323	V	96.6	Very high	95	Very high	56 Å²	56	33.8 Å²	33.8	34%	0.339	19%	0.187	S	C	.	.	H	α-helix	trans	-63.4	-37.5	179.1	170.7	0	0	0	0	110.8	G319 I320 L326 A327 T389	G319-V323 WeakPolarHBondContact O-CG2 3.19Å; G319-V323 PolarHBondContact O-N 3.29Å; I320-V323 PolarHBondContact O-N 3.02Å; V323-L326 PolarHBondContact O-N 3.21Å; V323-A327 WeakPolarHBondContact O-CB 3.37Å; V323-A327 PolarHBondContact O-N 3.14Å; V323-T389 HydrophobicContact CG1-CG2 4.35Å
324	F	96.1	Very high	95.2	Very high	25 Å²	25	32 Å²	32	11%	0.11	18%	0.18	C	C	.	.	H	α-helix	trans	-64.5	-52.3	177.5	-153.4	-74.4	0	0	0	111.6	K207 M210 I211 I220 I320 I321 L322 L326 A327 E328	K207-F324 HydrophobicContact CB-CZ 4.23Å; K207-F324 HydrophobicContact CD-CE1 4.15Å; K207-F324 HydrophobicContact CD-CZ 4.32Å; K207-F324 HydrophobicContact CG-CE1 4.32Å; K207-F324 HydrophobicContact CG-CZ 3.99Å; M210-F324 HydrophobicContact CE-CD2 4.48Å; M210-F324 HydrophobicContact CE-CE2 3.25Å; M210-F324 HydrophobicContact CE-CZ 3.31Å; I211-F324 HydrophobicContact CD1-CD2 4.24Å; I211-F324 HydrophobicContact CD1-CE1 4.37Å; I211-F324 HydrophobicContact CD1-CE2 3.61Å; I211-F324 HydrophobicContact CD1-CZ 3.7Å; I211-F324 HydrophobicContact CG1-CD2 4.3Å; I211-F324 HydrophobicContact CG1-CE2 3.67Å; I211-F324 HydrophobicContact CG1-CZ 4.2Å; I220-F324 HydrophobicContact CD1-CB 4.2Å; I220-F324 HydrophobicContact CD1-CD1 4.31Å; I220-F324 HydrophobicContact CD1-CD2 4.41Å; I220-F324 HydrophobicContact CD1-CG 4.07Å; I220-F324 HydrophobicContact CG2-CD1 3.75Å; I220-F324 HydrophobicContact CG2-CE1 4.2Å; I220-F324 HydrophobicContact CG2-CG 4.46Å; I320-F324 WeakPolarHBondContact O-CB 3.41Å; I320-F324 PolarHBondContact O-N 3.4Å; I321-F324 PolarHBondContact O-N 3.4Å; L322-F324 VanDerWaalsContact C-N 3.28Å; L322-F324 PolarHBondContact O-N 3.4Å; F324-L326 VanDerWaalsContact C-N 3.26Å; F324-L326 PolarHBondContact O-N 2.73Å; F324-A327 PolarHBondContact O-N 2.83Å; F324-A327 VanDerWaalsContact O-N 3.16Å; F324-E328 HydrophobicContact CD1-CG 4.05Å; F324-E328 HydrophobicContact CE1-CG 4.12Å; F324-E328 WeakPolarHBondContact CE1-OE1 3.37Å; F324-E328 WeakPolarHBondContact O-CG 3.41Å; F324-E328 PolarHBondContact O-N 3.3Å
325	L	97.2	Very high	95.2	Very high	10 Å²	10	31 Å²	31	5%	0.052	18%	0.177	C	C	.	.	H	α-helix	trans	-59.6	-39.8	177.5	-68.2	171.6	0	0	0	111.2	I220 M223 F224 L227 I321 L322 E328 L329	I220-L325 HydrophobicContact CG2-CD2 3.8Å; I220-L325 HydrophobicContact CG2-CG 4.44Å; M223-L325 HydrophobicContact CB-CD1 3.83Å; M223-L325 HydrophobicContact CB-CD2 4.08Å; M223-L325 HydrophobicContact CE-CD1 3.57Å; M223-L325 HydrophobicContact SD-CD1 3.99Å; F224-L325 HydrophobicContact CB-CD2 4Å; F224-L325 HydrophobicContact CD2-CD2 4.2Å; L227-L325 HydrophobicContact CD1-CB 3.98Å; L227-L325 HydrophobicContact CD1-CD1 4.24Å; L227-L325 HydrophobicContact CD1-CD2 4.06Å; L227-L325 HydrophobicContact CD1-CG 4.32Å; I321-L325 HydrophobicContact CG2-CD1 3.79Å; I321-L325 HydrophobicContact CG2-CG 4.34Å; I321-L325 VanDerWaalsContact O-CG 3.31Å; I321-L325 WeakPolarHBondContact O-CG 3.17Å; I321-L325 PolarHBondContact O-N 3.37Å; L322-L325 PolarHBondContact O-N 2.85Å; L325-E328 PolarHBondContact O-N 3.02Å; L325-L329 VanDerWaalsContact O-CB 3.3Å; L325-L329 WeakPolarHBondContact O-CB 3.46Å; L325-L329 PolarHBondContact O-N 2.99Å
326	L	97.5	Very high	95.1	Very high	41 Å²	41	28.9 Å²	28.9	22%	0.215	16%	0.163	C	C	.	.	H	α-helix	trans	-64.9	-43.4	176.2	-177.8	60	0	0	0	112	L322 V323 F324 E328 L329 N330 T389 L393	L322-L326 VanDerWaalsContact O-CB 3.27Å; L322-L326 WeakPolarHBondContact O-CB 3.39Å; L322-L326 PolarHBondContact O-N 3.4Å; V323-L326 PolarHBondContact O-N 3.21Å; F324-L326 VanDerWaalsContact C-N 3.26Å; F324-L326 PolarHBondContact O-N 2.73Å; L326-E328 VanDerWaalsContact C-N 3.3Å; L326-E328 PolarHBondContact O-N 3.5Å; L326-L329 PolarHBondContact O-N 3.12Å; L326-N330 WeakPolarHBondContact O-CB 3.42Å; L326-N330 PolarHBondContact O-N 3.25Å; L326-N330 PolarHBondContact O-OD1 3.39Å; L326-T389 HydrophobicContact CB-CG2 3.97Å; L326-T389 HydrophobicContact CD2-CG2 3.77Å; L326-T389 HydrophobicContact CG-CG2 3.66Å; L326-L393 HydrophobicContact CD1-CB 4.26Å; L326-L393 HydrophobicContact CD1-CD1 4.03Å; L326-L393 HydrophobicContact CD1-CD2 3.99Å; L326-L393 HydrophobicContact CD1-CG 4.3Å; L326-L393 HydrophobicContact CD2-CB 4.42Å; L326-L393 HydrophobicContact CD2-CD2 3.9Å
327	A	96.8	Very high	95.2	Very high	11 Å²	11	27.5 Å²	27.5	9%	0.091	15%	0.152	C	C	.	.	H	α-helix	trans	-63.4	-36.5	176.2	0	0	0	0	0	112.1	V323 F324 T331 R350 F354 T389	V323-A327 WeakPolarHBondContact O-CB 3.37Å; V323-A327 PolarHBondContact O-N 3.14Å; F324-A327 PolarHBondContact O-N 2.83Å; F324-A327 VanDerWaalsContact O-N 3.16Å; A327-T331 PolarHBondContact O-N 3.45Å; A327-T331 PolarHBondContact O-OG1 2.89Å; A327-R350 PolarHBondContact O-NH1 3.12Å; A327-R350 PolarHBondContact O-NH2 3.23Å; A327-F354 HydrophobicContact CB-CD1 4.47Å; A327-F354 HydrophobicContact CB-CE1 3.91Å; A327-F354 HydrophobicContact CB-CZ 4.23Å; A327-T389 HydrophobicContact CB-CG2 3.96Å
328	E	95.1	Very high	95.2	Very high	18 Å²	18	27.9 Å²	27.9	8%	0.084	15%	0.154	C	C	.	.	H	α-helix	trans	-67	-49.1	173.5	-69.2	-171.9	138.9	0	0	111.2	K207 F224 F324 L325 L326 N330 T331 F332	K207-E328 WeakPolarHBondContact CD-OE1 3.45Å; K207-E328 WeakPolarHBondContact CE-OE1 3.38Å; K207-E328 IonicContact NZ-OE1 3.07Å; K207-E328 PolarHBondContact NZ-OE1 3.4Å; F224-E328 HydrophobicContact CD2-CB 3.84Å; F224-E328 WeakPolarHBondContact CD2-OE2 3.16Å; F224-E328 HydrophobicContact CE2-CB 3.46Å; F224-E328 VanDerWaalsContact CE2-CB 3.46Å; F224-E328 HydrophobicContact CZ-CB 4.21Å; F324-E328 HydrophobicContact CD1-CG 4.05Å; F324-E328 HydrophobicContact CE1-CG 4.12Å; F324-E328 WeakPolarHBondContact CE1-OE1 3.37Å; F324-E328 WeakPolarHBondContact O-CG 3.41Å; F324-E328 PolarHBondContact O-N 3.3Å; L325-E328 PolarHBondContact O-N 3.02Å; L326-E328 VanDerWaalsContact C-N 3.3Å; L326-E328 PolarHBondContact O-N 3.5Å; E328-N330 VanDerWaalsContact C-N 3.33Å; E328-N330 PolarHBondContact O-N 3.16Å; E328-T331 WeakPolarHBondContact O-CA 3.49Å; E328-T331 WeakPolarHBondContact O-CB 3.3Å; E328-T331 PolarHBondContact O-N 2.85Å; E328-T331 PolarHBondContact O-OG1 3.21Å; E328-F332 WeakPolarHBondContact O-CD2 3.26Å
329	L	95.5	Very high	95.1	Very high	26 Å²	26	29 Å²	29	14%	0.136	15%	0.152	C	C	.	.	H	α-helix	trans	-59.8	-42.9	179.3	-163.3	66.1	0	0	0	111.9	L231 F238 L325 L326 T331 F332 Y333	L231-L329 HydrophobicContact CD1-CD1 3.65Å; L231-L329 HydrophobicContact CD1-CD2 3.76Å; L231-L329 HydrophobicContact CD1-CG 4.31Å; F238-L329 HydrophobicContact CE2-CD1 3.98Å; F238-L329 HydrophobicContact CZ-CD1 3.88Å; L325-L329 VanDerWaalsContact O-CB 3.3Å; L325-L329 WeakPolarHBondContact O-CB 3.46Å; L325-L329 PolarHBondContact O-N 2.99Å; L326-L329 PolarHBondContact O-N 3.12Å; L329-T331 PolarHBondContact O-N 3.49Å; L329-T331 VanDerWaalsContact O-N 3.12Å; L329-F332 PolarHBondContact O-N 3.36Å; L329-Y333 HydrophobicContact CD1-CD2 4.13Å; L329-Y333 HydrophobicContact CD1-CE2 3.68Å; L329-Y333 HydrophobicContact CD2-CD2 4.41Å; L329-Y333 HydrophobicContact CD2-CE2 3.97Å; L329-Y333 HydrophobicContact CG-CD2 3.71Å; L329-Y333 HydrophobicContact CG-CE2 3.56Å; L329-Y333 WeakPolarHBondContact O-CD2 3.31Å; L329-Y333 PolarHBondContact O-N 2.96Å
330	N	96.8	Very high	95	Very high	2 Å²	2	28.5 Å²	28.5	1%	0.011	14%	0.142	C	C	.	.	H	α-helix	trans	-55.3	-30.5	174.2	-76	-10.4	0	0	0	112.5	L326 E328 F332 L334 T389 E392	L326-N330 WeakPolarHBondContact O-CB 3.42Å; L326-N330 PolarHBondContact O-N 3.25Å; L326-N330 PolarHBondContact O-OD1 3.39Å; E328-N330 VanDerWaalsContact C-N 3.33Å; E328-N330 PolarHBondContact O-N 3.16Å; N330-F332 VanDerWaalsContact C-N 3.26Å; N330-F332 PolarHBondContact O-N 2.98Å; N330-L334 HydrophobicContact CB-CD1 4.37Å; N330-L334 WeakPolarHBondContact O-CB 3.48Å; N330-L334 WeakPolarHBondContact O-CD1 3.31Å; N330-L334 WeakPolarHBondContact O-CG 3.39Å; N330-L334 PolarHBondContact O-N 3.06Å; N330-T389 PolarHBondContact ND2-O 3.16Å; N330-E392 HydrophobicContact CB-CB 4.16Å; N330-E392 WeakPolarHBondContact CB-OE2 3.19Å; N330-E392 WeakPolarHBondContact ND2-CB 3.38Å; N330-E392 PolarHBondContact ND2-OE2 3.24Å
331	T	94.4	Very high	94.7	Very high	16 Å²	16	29.8 Å²	29.8	10%	0.098	15%	0.151	C	C	.	.	H	α-helix	trans	-56.7	-43.3	174.6	-41.5	0	0	0	0	111.4	A327 E328 L329 K335 V347 R350 L351	A327-T331 PolarHBondContact O-N 3.45Å; A327-T331 PolarHBondContact O-OG1 2.89Å; E328-T331 WeakPolarHBondContact O-CA 3.49Å; E328-T331 WeakPolarHBondContact O-CB 3.3Å; E328-T331 PolarHBondContact O-N 2.85Å; E328-T331 PolarHBondContact O-OG1 3.21Å; L329-T331 PolarHBondContact O-N 3.49Å; L329-T331 VanDerWaalsContact O-N 3.12Å; T331-K335 WeakPolarHBondContact O-CG 3.3Å; T331-V347 HydrophobicContact CG2-CG1 4.13Å; T331-R350 PolarHBondContact OG1-NH1 3.18Å; T331-L351 HydrophobicContact CG2-CD2 4.11Å
332	F	93.3	Very high	94.2	Very high	48 Å²	48	31.4 Å²	31.4	21%	0.211	16%	0.163	C	C	.	.	H	α-helix	trans	-80.7	-41.2	-176.4	-66.3	-92.6	0	0	0	111.9	F224 L235 F238 E328 L329 N330 K335 F336	F224-F332 HydrophobicContact CE1-CE2 4.05Å; F224-F332 HydrophobicContact CE1-CZ 4.39Å; F224-F332 HydrophobicContact CE2-CE2 4.48Å; F224-F332 AromaticContact CZ-CD2 3.99Å; F224-F332 HydrophobicContact CZ-CD2 3.99Å; F224-F332 AromaticContact CZ-CE2 3.45Å; F224-F332 HydrophobicContact CZ-CE2 3.45Å; F224-F332 VanDerWaalsContact CZ-CE2 3.45Å; F224-F332 HydrophobicContact CZ-CZ 4.19Å; L235-F332 HydrophobicContact CD1-CB 4.19Å; F238-F332 HydrophobicContact CD1-CD1 4.31Å; F238-F332 HydrophobicContact CE1-CB 3.89Å; F238-F332 AromaticContact CE1-CD1 3.43Å; F238-F332 HydrophobicContact CE1-CD1 3.43Å; F238-F332 VanDerWaalsContact CE1-CD1 3.43Å; F238-F332 AromaticContact CE1-CD2 3.94Å; F238-F332 HydrophobicContact CE1-CD2 3.94Å; F238-F332 AromaticContact CE1-CE1 3.85Å; F238-F332 HydrophobicContact CE1-CE1 3.85Å; F238-F332 HydrophobicContact CE1-CE2 4.33Å; F238-F332 AromaticContact CE1-CG 3.48Å; F238-F332 HydrophobicContact CE1-CG 3.48Å; F238-F332 VanDerWaalsContact CE1-CG 3.48Å; F238-F332 HydrophobicContact CE1-CZ 4.27Å; F238-F332 HydrophobicContact CZ-CB 3.61Å; F238-F332 HydrophobicContact CZ-CD1 4.09Å; F238-F332 HydrophobicContact CZ-CD2 4.08Å; F238-F332 AromaticContact CZ-CG 3.67Å; F238-F332 HydrophobicContact CZ-CG 3.67Å; E328-F332 WeakPolarHBondContact O-CD2 3.26Å; L329-F332 PolarHBondContact O-N 3.36Å; N330-F332 VanDerWaalsContact C-N 3.26Å; N330-F332 PolarHBondContact O-N 2.98Å; F332-K335 WeakPolarHBondContact O-CG 3.5Å; F332-F336 WeakPolarHBondContact O-CB 3.16Å; F332-F336 PolarHBondContact O-N 3.35Å; F332-F336 VanDerWaalsContact O-N 3.16Å
333	Y	94.9	Very high	93.6	Very high	8 Å²	8	33.7 Å²	33.7	3%	0.031	17%	0.17	C	C	.	.	H	α-helix	trans	-72.5	-40.1	178.8	-80.4	-93.7	0	0	0	112.7	L231 Q234 L235 F238 L329 K335 F336 V337 V396 L404	L231-Y333 HydrophobicContact CD1-CE2 4.39Å; Q234-Y333 PolarHBondContact OE1-OH 2.93Å; L235-Y333 HydrophobicContact CD1-CD1 4.07Å; L235-Y333 HydrophobicContact CD1-CD2 3.73Å; L235-Y333 HydrophobicContact CD1-CE1 3.93Å; L235-Y333 HydrophobicContact CD1-CE2 3.56Å; L235-Y333 HydrophobicContact CD1-CG 3.99Å; L235-Y333 HydrophobicContact CG-CE1 4.12Å; L235-Y333 HydrophobicContact CG-CE2 4.43Å; F238-Y333 HydrophobicContact CE2-CE2 4.33Å; L329-Y333 HydrophobicContact CD1-CD2 4.13Å; L329-Y333 HydrophobicContact CD1-CE2 3.68Å; L329-Y333 HydrophobicContact CD2-CD2 4.41Å; L329-Y333 HydrophobicContact CD2-CE2 3.97Å; L329-Y333 HydrophobicContact CG-CD2 3.71Å; L329-Y333 HydrophobicContact CG-CE2 3.56Å; L329-Y333 WeakPolarHBondContact O-CD2 3.31Å; L329-Y333 PolarHBondContact O-N 2.96Å; Y333-K335 PolarHBondContact O-N 2.94Å; Y333-F336 WeakPolarHBondContact O-CB 3.5Å; Y333-F336 PolarHBondContact O-N 3.12Å; Y333-F336 VanDerWaalsContact O-N 3.16Å; Y333-V337 WeakPolarHBondContact O-CG1 3.28Å; Y333-V337 WeakPolarHBondContact O-CG2 3.12Å; Y333-V337 PolarHBondContact O-N 3.38Å; Y333-V396 VanDerWaalsContact CB-CG1 3.47Å; Y333-V396 HydrophobicContact CD1-CG1 3.6Å; Y333-V396 HydrophobicContact CG-CG1 3.76Å; Y333-L404 HydrophobicContact CD1-CD2 4.15Å; Y333-L404 HydrophobicContact CE1-CD2 3.62Å
334	L	94.8	Very high	93.3	Very high	7 Å²	7	32 Å²	32	4%	0.037	16%	0.159	C	C	.	.	H	α-helix	trans	-61.5	-44.9	178.1	-75	170	0	0	0	111.4	N330 F336 L338 M340 E392 I395 V396	N330-L334 HydrophobicContact CB-CD1 4.37Å; N330-L334 WeakPolarHBondContact O-CB 3.48Å; N330-L334 WeakPolarHBondContact O-CD1 3.31Å; N330-L334 WeakPolarHBondContact O-CG 3.39Å; N330-L334 PolarHBondContact O-N 3.06Å; L334-F336 VanDerWaalsContact C-N 3.25Å; L334-F336 PolarHBondContact O-N 2.96Å; L334-L338 HydrophobicContact CD2-CD1 4.41Å; L334-L338 VanDerWaalsContact O-CB 3.23Å; L334-L338 WeakPolarHBondContact O-CB 3.49Å; L334-L338 PolarHBondContact O-N 2.85Å; L334-M340 HydrophobicContact CB-CE 4.49Å; L334-E392 HydrophobicContact CD1-CB 3.93Å; L334-E392 HydrophobicContact CD1-CG 3.65Å; L334-I395 HydrophobicContact CD2-CB 4.3Å; L334-I395 HydrophobicContact CD2-CG2 3.99Å; L334-V396 HydrophobicContact CD2-CG2 3.95Å; L334-V396 HydrophobicContact CG-CG2 4.09Å
335	K	92.6	Very high	93.2	Very high	21 Å²	21	35.4 Å²	35.4	9%	0.091	17%	0.171	C	C	.	.	H	α-helix	trans	-62.4	-37	176.9	74.3	175.3	-172.4	-170.9	0	111.4	T331 F332 Y333 W339 M340 V347	T331-K335 WeakPolarHBondContact O-CG 3.3Å; F332-K335 WeakPolarHBondContact O-CG 3.5Å; Y333-K335 PolarHBondContact O-N 2.94Å; K335-W339 WeakPolarHBondContact O-CA 3.23Å; K335-W339 PolarHBondContact O-N 3.44Å; K335-W339 VanDerWaalsContact O-N 3.14Å; K335-M340 HydrophobicContact CB-CB 4.07Å; K335-M340 HydrophobicContact CB-CE 4.33Å; K335-M340 PolarHBondContact O-N 2.85Å; K335-V347 HydrophobicContact CB-CG2 4.23Å
336	F	92	Very high	93	Very high	55 Å²	55	37 Å²	37	24%	0.241	18%	0.18	C	C	.	.	H	α-helix	trans	-66.8	-56.6	176.9	175.7	-105.4	0	0	0	112.1	L235 F332 Y333 L334 L338 W339 D400 T403	L235-F336 HydrophobicContact CD2-CB 3.85Å; L235-F336 HydrophobicContact CD2-CD1 3.53Å; L235-F336 HydrophobicContact CD2-CD2 3.66Å; L235-F336 HydrophobicContact CD2-CE1 3.9Å; L235-F336 HydrophobicContact CD2-CE2 4.03Å; L235-F336 HydrophobicContact CD2-CG 3.39Å; L235-F336 HydrophobicContact CD2-CZ 4.13Å; F332-F336 WeakPolarHBondContact O-CB 3.16Å; F332-F336 PolarHBondContact O-N 3.35Å; F332-F336 VanDerWaalsContact O-N 3.16Å; Y333-F336 WeakPolarHBondContact O-CB 3.5Å; Y333-F336 PolarHBondContact O-N 3.12Å; Y333-F336 VanDerWaalsContact O-N 3.16Å; L334-F336 VanDerWaalsContact C-N 3.25Å; L334-F336 PolarHBondContact O-N 2.96Å; F336-L338 VanDerWaalsContact C-N 3.29Å; F336-L338 PolarHBondContact O-N 3.48Å; F336-W339 PolarHBondContact O-N 3.2Å; F336-D400 WeakPolarHBondContact CE1-OD2 3.38Å; F336-T403 HydrophobicContact CE1-CG2 4.28Å
337	V	94	Very high	92.7	Very high	1 Å²	1	35.8 Å²	35.8	1%	0.006	17%	0.174	C	C	.	.	H	α-helix	trans	-68.5	-27.3	-174.4	-56.9	0	0	0	0	113	R151 Y333 V396 D400	R151-V337 VanDerWaalsContact CZ-O 3.3Å; R151-V337 PolarHBondContact NE-O 3.34Å; R151-V337 PolarHBondContact NH2-O 2.94Å; Y333-V337 WeakPolarHBondContact O-CG1 3.28Å; Y333-V337 WeakPolarHBondContact O-CG2 3.12Å; Y333-V337 PolarHBondContact O-N 3.38Å; V337-V396 HydrophobicContact CG1-CG1 4.5Å; V337-D400 HydrophobicContact CG1-CB 3.84Å
338	L	94.1	Very high	92.5	Very high	15 Å²	15	40.5 Å²	40.5	8%	0.079	20%	0.197	C	C	.	.	T	Hydrogen-bonded Turn	trans	-96.3	2.2	178	-65.7	172.4	0	0	0	114.3	I142 L154 L334 F336 M340 Y399	I142-L338 HydrophobicContact CG2-CD2 4.45Å; L154-L338 HydrophobicContact CD1-CB 3.82Å; L154-L338 HydrophobicContact CD1-CD1 4.47Å; L154-L338 HydrophobicContact CD1-CD2 4.45Å; L154-L338 HydrophobicContact CD1-CG 4.48Å; L334-L338 HydrophobicContact CD2-CD1 4.41Å; L334-L338 VanDerWaalsContact O-CB 3.23Å; L334-L338 WeakPolarHBondContact O-CB 3.49Å; L334-L338 PolarHBondContact O-N 2.85Å; F336-L338 VanDerWaalsContact C-N 3.29Å; F336-L338 PolarHBondContact O-N 3.48Å; L338-M340 HydrophobicContact CB-CE 4.16Å; L338-M340 HydrophobicContact CB-CG 4.29Å; L338-M340 HydrophobicContact CD1-CE 3.99Å; L338-Y399 HydrophobicContact CD2-CD2 3.95Å; L338-Y399 HydrophobicContact CD2-CE2 3.58Å
339	W	92.9	Very high	92.4	Very high	65 Å²	65	44.3 Å²	44.3	25%	0.246	22%	0.217	C	C	.	.	T	Hydrogen-bonded Turn	trans	55.5	49	-177.3	-57.4	-24.9	0	0	0	113.9	R151 V163 P164 L165 K335 F336	R151-W339 HydrophobicContact CB-CE3 4.32Å; R151-W339 HydrophobicContact CG-CD2 4.35Å; R151-W339 HydrophobicContact CG-CE3 4.2Å; R151-W339 VanDerWaalsContact CZ-CE2 3.45Å; V163-W339 VanDerWaalsContact O-CB 3.31Å; V163-W339 WeakPolarHBondContact O-CB 3.42Å; P164-W339 HydrophobicContact CB-CH2 4.49Å; P164-W339 HydrophobicContact CB-CZ2 4.26Å; P164-W339 HydrophobicContact CG-CE3 4.34Å; P164-W339 HydrophobicContact CG-CH2 3.67Å; P164-W339 HydrophobicContact CG-CZ2 3.88Å; P164-W339 HydrophobicContact CG-CZ3 3.91Å; L165-W339 HydrophobicContact CG-CB 4.46Å; K335-W339 WeakPolarHBondContact O-CA 3.23Å; K335-W339 PolarHBondContact O-N 3.44Å; K335-W339 VanDerWaalsContact O-N 3.14Å; F336-W339 PolarHBondContact O-N 3.2Å
340	M	92	Very high	92.4	Very high	22 Å²	22	44.2 Å²	44.2	11%	0.108	22%	0.215	C	C	.	.			trans	-98.1	126.7	172.4	-61.8	-176.2	-69	0	0	110.4	L154 L161 L165 L334 K335 L338 L346 V347	L154-M340 HydrophobicContact CD1-CG 4.05Å; L154-M340 HydrophobicContact CD1-SD 4.23Å; L161-M340 HydrophobicContact CD2-CG 4.24Å; L165-M340 VanDerWaalsContact CD1-C 3.42Å; L165-M340 WeakPolarHBondContact CD1-O 3.21Å; L334-M340 HydrophobicContact CB-CE 4.49Å; K335-M340 HydrophobicContact CB-CB 4.07Å; K335-M340 HydrophobicContact CB-CE 4.33Å; K335-M340 PolarHBondContact O-N 2.85Å; L338-M340 HydrophobicContact CB-CE 4.16Å; L338-M340 HydrophobicContact CB-CG 4.29Å; L338-M340 HydrophobicContact CD1-CE 3.99Å; M340-L346 HydrophobicContact SD-CB 4.25Å; M340-L346 HydrophobicContact SD-CD1 4.09Å; M340-V347 HydrophobicContact CB-CG2 4.49Å
341	P	89.6	Confident	92.2	Very high	43 Å²	43	48 Å²	48	28%	0.279	24%	0.235	S	C	.	.			trans	-58.9	147.7	174	-22.9	30.7	0	0	0	111.8	L165 E343 H344	L165-P341 HydrophobicContact CD1-CG 4.28Å; L165-P341 HydrophobicContact CD2-CG 3.91Å; P341-E343 VanDerWaalsContact C-N 3.26Å; P341-E343 PolarHBondContact O-N 3.22Å; P341-H344 HydrophobicContact CB-CB 4.25Å; P341-H344 HydrophobicContact CG-CB 4.46Å; P341-H344 WeakPolarHBondContact O-CB 3.44Å; P341-H344 PolarHBondContact O-N 3.36Å
342	P	84.6	Confident	92.2	Very high	51 Å²	51	50.3 Å²	50.3	33%	0.331	25%	0.249	S	C	.	.	T	Hydrogen-bonded Turn	trans	-56.5	-38	177.2	-26.1	34.8	0	0	0	113.9	H344	P342-H344 PolarHBondContact O-N 2.74Å
343	E	84.8	Confident	92.3	Very high	167 Å²	167	48.5 Å²	48.5	78%	0.78	24%	0.241	S	C	*	.	T	Hydrogen-bonded Turn	trans	-79.7	-1.9	-179.9	-64.3	165.4	-142.4	0	0	113.2	P341 Y345	P341-E343 VanDerWaalsContact C-N 3.26Å; P341-E343 PolarHBondContact O-N 3.22Å; E343-Y345 PolarHBondContact O-N 3.3Å
344	H	91.1	Very high	92.4	Very high	20 Å²	20	49.4 Å²	49.4	9%	0.093	25%	0.245	C	C	.	.			trans	-67.6	136.7	-175.8	-165.9	-92.2	0	0	0	111.4	D158 P341 P342 L346 V347 L348	D158-H344 IonicContact OD2-NE2 2.68Å; D158-H344 PolarHBondContact OD2-NE2 3.24Å; P341-H344 HydrophobicContact CB-CB 4.25Å; P341-H344 HydrophobicContact CG-CB 4.46Å; P341-H344 WeakPolarHBondContact O-CB 3.44Å; P341-H344 PolarHBondContact O-N 3.36Å; P342-H344 PolarHBondContact O-N 2.74Å; H344-L346 VanDerWaalsContact CE1-CG 3.49Å; H344-L346 WeakPolarHBondContact CE1-CG 3.46Å; H344-L346 WeakPolarHBondContact ND1-CB 3.41Å; H344-L346 WeakPolarHBondContact ND1-CG 3.39Å; H344-L346 PolarHBondContact ND1-N 2.97Å; H344-L346 PolarHBondContact O-N 3.24Å; H344-V347 HydrophobicContact CB-CG2 4.48Å; H344-V347 WeakPolarHBondContact O-CB 3.4Å; H344-V347 PolarHBondContact O-N 3.08Å; H344-L348 PolarHBondContact O-N 3.07Å
345	Y	92.8	Very high	92.3	Very high	97 Å²	97	51.8 Å²	51.8	38%	0.38	26%	0.26	S	S	.	.	H	α-helix	trans	-59.9	-26	-175.1	69	-92.3	0	0	0	113.5	V157 D158 E343 V347 L348 L349	V157-Y345 WeakPolarHBondContact CG1-OH 3.39Å; D158-Y345 HydrophobicContact CB-CE1 4.42Å; E343-Y345 PolarHBondContact O-N 3.3Å; Y345-V347 VanDerWaalsContact C-N 3.3Å; Y345-V347 PolarHBondContact O-N 2.94Å; Y345-L348 PolarHBondContact O-N 2.86Å; Y345-L349 HydrophobicContact CD2-CD1 3.73Å; Y345-L349 HydrophobicContact CD2-CG 4.45Å; Y345-L349 HydrophobicContact CE2-CD1 4.18Å; Y345-L349 WeakPolarHBondContact O-CB 3.23Å; Y345-L349 VanDerWaalsContact O-CG 3.27Å; Y345-L349 WeakPolarHBondContact O-CG 3.3Å; Y345-L349 PolarHBondContact O-N 2.92Å
346	L	93.1	Very high	92.4	Very high	43 Å²	43	52 Å²	52	23%	0.225	26%	0.262	C	S	.	.	H	α-helix	trans	-63.1	-35.8	174.1	-68.2	173.2	0	0	0	112.5	V157 L161 M340 H344 L349 R350	V157-L346 HydrophobicContact CG1-CD1 4.03Å; V157-L346 HydrophobicContact CG1-CD2 4.11Å; L161-L346 HydrophobicContact CD1-CD1 3.89Å; M340-L346 HydrophobicContact SD-CB 4.25Å; M340-L346 HydrophobicContact SD-CD1 4.09Å; H344-L346 VanDerWaalsContact CE1-CG 3.49Å; H344-L346 WeakPolarHBondContact CE1-CG 3.46Å; H344-L346 WeakPolarHBondContact ND1-CB 3.41Å; H344-L346 WeakPolarHBondContact ND1-CG 3.39Å; H344-L346 PolarHBondContact ND1-N 2.97Å; H344-L346 PolarHBondContact O-N 3.24Å; L346-L349 HydrophobicContact CD2-CD1 4.4Å; L346-L349 PolarHBondContact O-N 2.9Å; L346-R350 WeakPolarHBondContact O-CB 3.46Å; L346-R350 PolarHBondContact O-N 2.71Å
347	V	92.4	Very high	92.6	Very high	15 Å²	15	49.4 Å²	49.4	9%	0.091	25%	0.251	C	S	.	.	H	α-helix	trans	-66.5	-46.6	175.5	-177	0	0	0	0	109.1	T331 K335 M340 H344 Y345 L349 R350 L351	T331-V347 HydrophobicContact CG2-CG1 4.13Å; K335-V347 HydrophobicContact CB-CG2 4.23Å; M340-V347 HydrophobicContact CB-CG2 4.49Å; H344-V347 HydrophobicContact CB-CG2 4.48Å; H344-V347 WeakPolarHBondContact O-CB 3.4Å; H344-V347 PolarHBondContact O-N 3.08Å; Y345-V347 VanDerWaalsContact C-N 3.3Å; Y345-V347 PolarHBondContact O-N 2.94Å; V347-L349 PolarHBondContact O-N 3.16Å; V347-R350 WeakPolarHBondContact O-CB 3.38Å; V347-R350 PolarHBondContact O-N 3.46Å; V347-L351 WeakPolarHBondContact O-CG 3.19Å; V347-L351 PolarHBondContact O-N 3.14Å
348	L	91	Very high	92.7	Very high	110 Å²	110	49.7 Å²	49.7	58%	0.576	25%	0.254	S	S	*	.	H	α-helix	trans	-61.2	-44.5	175.5	-179.7	61.8	0	0	0	112.4	H344 Y345 R350 L351 V352	H344-L348 PolarHBondContact O-N 3.07Å; Y345-L348 PolarHBondContact O-N 2.86Å; L348-R350 VanDerWaalsContact C-N 3.27Å; L348-R350 PolarHBondContact O-N 2.98Å; L348-L351 WeakPolarHBondContact O-CB 3.15Å; L348-L351 PolarHBondContact O-N 3.34Å; L348-L351 VanDerWaalsContact O-N 3.12Å; L348-V352 HydrophobicContact CD1-CG2 4.47Å; L348-V352 WeakPolarHBondContact O-CG2 3.47Å; L348-V352 PolarHBondContact O-N 2.96Å
349	L	93.8	Very high	92.6	Very high	98 Å²	98	49.3 Å²	49.3	51%	0.513	25%	0.254	S	S	.	.	H	α-helix	trans	-60.2	-38.9	177	-77.2	176.4	0	0	0	111.4	Y345 L346 V347 V352 F353	Y345-L349 HydrophobicContact CD2-CD1 3.73Å; Y345-L349 HydrophobicContact CD2-CG 4.45Å; Y345-L349 HydrophobicContact CE2-CD1 4.18Å; Y345-L349 WeakPolarHBondContact O-CB 3.23Å; Y345-L349 VanDerWaalsContact O-CG 3.27Å; Y345-L349 WeakPolarHBondContact O-CG 3.3Å; Y345-L349 PolarHBondContact O-N 2.92Å; L346-L349 HydrophobicContact CD2-CD1 4.4Å; L346-L349 PolarHBondContact O-N 2.9Å; V347-L349 PolarHBondContact O-N 3.16Å; L349-V352 PolarHBondContact O-N 2.65Å; L349-F353 VanDerWaalsContact O-CB 3.3Å; L349-F353 WeakPolarHBondContact O-CB 3.34Å; L349-F353 PolarHBondContact O-N 3.28Å
350	R	94.9	Very high	92.7	Very high	24 Å²	24	46.8 Å²	46.8	9%	0.091	25%	0.245	C	C	.	.	H	α-helix	trans	-63.7	-42.4	174.2	-173.1	-179.5	170.6	-77	3.7	111.5	A327 T331 L346 V347 L348 F353 F354 E392	A327-R350 PolarHBondContact O-NH1 3.12Å; A327-R350 PolarHBondContact O-NH2 3.23Å; T331-R350 PolarHBondContact OG1-NH1 3.18Å; L346-R350 WeakPolarHBondContact O-CB 3.46Å; L346-R350 PolarHBondContact O-N 2.71Å; V347-R350 WeakPolarHBondContact O-CB 3.38Å; V347-R350 PolarHBondContact O-N 3.46Å; L348-R350 VanDerWaalsContact C-N 3.27Å; L348-R350 PolarHBondContact O-N 2.98Å; R350-F353 WeakPolarHBondContact O-CB 3.29Å; R350-F353 PolarHBondContact O-N 3.38Å; R350-F354 HydrophobicContact CG-CD2 3.98Å; R350-F354 HydrophobicContact CG-CE2 4.05Å; R350-F354 VanDerWaalsContact CZ-CE2 3.44Å; R350-F354 WeakPolarHBondContact O-CD2 3.43Å; R350-F354 PolarHBondContact O-N 3.04Å; R350-E392 IonicContact CZ-OE1 3.06Å; R350-E392 IonicContact CZ-OE2 3.15Å; R350-E392 IonicContact NE-OE1 3.38Å; R350-E392 PolarHBondContact NE-OE1 2.83Å; R350-E392 IonicContact NE-OE2 2.73Å; R350-E392 IonicContact NH2-OE1 3.15Å; R350-E392 PolarHBondContact NH2-OE1 2.97Å; R350-E392 IonicContact NH2-OE2 3.16Å; R350-E392 PolarHBondContact NH2-OE2 3.42Å
351	L	93.2	Very high	93	Very high	83 Å²	83	45.9 Å²	45.9	44%	0.435	24%	0.242	S	C	.	.	H	α-helix	trans	-61.9	-46.9	175.2	-65.1	176.7	0	0	0	111.6	T331 V347 L348 F353 F354 V355	T331-L351 HydrophobicContact CG2-CD2 4.11Å; V347-L351 WeakPolarHBondContact O-CG 3.19Å; V347-L351 PolarHBondContact O-N 3.14Å; L348-L351 WeakPolarHBondContact O-CB 3.15Å; L348-L351 PolarHBondContact O-N 3.34Å; L348-L351 VanDerWaalsContact O-N 3.12Å; L351-F353 VanDerWaalsContact C-N 3.29Å; L351-F353 PolarHBondContact O-N 3.44Å; L351-F354 PolarHBondContact O-N 3.42Å; L351-V355 WeakPolarHBondContact O-CG2 3.21Å; L351-V355 PolarHBondContact O-N 2.95Å
352	V	93.9	Very high	93.2	Very high	63 Å²	63	44.3 Å²	44.3	38%	0.382	23%	0.231	S	C	.	.	H	α-helix	trans	-60	-41.1	175.7	173.3	0	0	0	0	111	W128 L348 L349 V355 N356	W128-V352 HydrophobicContact CH2-CG1 4.17Å; W128-V352 HydrophobicContact CZ2-CG1 4.45Å; L348-V352 HydrophobicContact CD1-CG2 4.47Å; L348-V352 WeakPolarHBondContact O-CG2 3.47Å; L348-V352 PolarHBondContact O-N 2.96Å; L349-V352 PolarHBondContact O-N 2.65Å; V352-V355 PolarHBondContact O-N 3.12Å; V352-N356 PolarHBondContact O-N 3.48Å; V352-N356 PolarHBondContact O-ND2 2.93Å
353	F	96.5	Very high	93.6	Very high	11 Å²	11	43 Å²	43	5%	0.048	22%	0.219	C	C	.	.	H	α-helix	trans	-56.8	-55.8	174.9	169.1	-94.2	0	0	0	110.9	W128 V131 S132 Y135 L349 R350 L351 V355 N356 V357 I388	W128-F353 AromaticContact CE3-CD2 3.91Å; W128-F353 HydrophobicContact CE3-CD2 3.91Å; W128-F353 HydrophobicContact CZ3-CB 4.05Å; W128-F353 AromaticContact CZ3-CD2 3.77Å; W128-F353 HydrophobicContact CZ3-CD2 3.77Å; W128-F353 HydrophobicContact CZ3-CG 4.37Å; V131-F353 HydrophobicContact CG1-CD2 3.93Å; V131-F353 HydrophobicContact CG1-CE2 4.01Å; S132-F353 VanDerWaalsContact OG-CE2 3.31Å; S132-F353 WeakPolarHBondContact OG-CE2 3.43Å; S132-F353 WeakPolarHBondContact OG-CZ 3.23Å; Y135-F353 HydrophobicContact CD1-CD1 4.32Å; Y135-F353 AromaticContact CD1-CE1 3.77Å; Y135-F353 HydrophobicContact CD1-CE1 3.77Å; Y135-F353 HydrophobicContact CD1-CE2 4.46Å; Y135-F353 AromaticContact CD1-CZ 3.86Å; Y135-F353 HydrophobicContact CD1-CZ 3.86Å; Y135-F353 HydrophobicContact CE1-CD1 4.45Å; Y135-F353 HydrophobicContact CE1-CE1 4.13Å; L349-F353 VanDerWaalsContact O-CB 3.3Å; L349-F353 WeakPolarHBondContact O-CB 3.34Å; L349-F353 PolarHBondContact O-N 3.28Å; R350-F353 WeakPolarHBondContact O-CB 3.29Å; R350-F353 PolarHBondContact O-N 3.38Å; L351-F353 VanDerWaalsContact C-N 3.29Å; L351-F353 PolarHBondContact O-N 3.44Å; F353-V355 VanDerWaalsContact C-N 3.34Å; F353-V355 PolarHBondContact O-N 3.45Å; F353-N356 PolarHBondContact O-N 2.91Å; F353-N356 VanDerWaalsContact O-N 3.1Å; F353-V357 HydrophobicContact CD1-CG2 4.11Å; F353-V357 HydrophobicContact CD2-CG1 4.11Å; F353-V357 HydrophobicContact CE1-CG2 3.77Å; F353-V357 HydrophobicContact CE2-CG1 3.76Å; F353-V357 HydrophobicContact CE2-CG2 4.5Å; F353-V357 HydrophobicContact CZ-CG1 3.97Å; F353-V357 HydrophobicContact CZ-CG2 3.98Å; F353-V357 WeakPolarHBondContact O-CG2 3.28Å; F353-V357 PolarHBondContact O-N 3.28Å; F353-I388 HydrophobicContact CE1-CD1 4.1Å; F353-I388 HydrophobicContact CZ-CD1 3.72Å
354	F	96.3	Very high	94	Very high	27 Å²	27	36 Å²	36	12%	0.118	19%	0.186	C	C	.	.	H	α-helix	trans	-62.3	-35.8	-178.1	-89.7	-80.7	0	0	0	113.6	A327 R350 L351 N356 G358 V385 I388	A327-F354 HydrophobicContact CB-CD1 4.47Å; A327-F354 HydrophobicContact CB-CE1 3.91Å; A327-F354 HydrophobicContact CB-CZ 4.23Å; R350-F354 HydrophobicContact CG-CD2 3.98Å; R350-F354 HydrophobicContact CG-CE2 4.05Å; R350-F354 VanDerWaalsContact CZ-CE2 3.44Å; R350-F354 WeakPolarHBondContact O-CD2 3.43Å; R350-F354 PolarHBondContact O-N 3.04Å; L351-F354 PolarHBondContact O-N 3.42Å; F354-N356 VanDerWaalsContact C-N 3.32Å; F354-N356 PolarHBondContact O-N 3.42Å; F354-G358 WeakPolarHBondContact O-CA 3.36Å; F354-G358 PolarHBondContact O-N 2.94Å; F354-V385 HydrophobicContact CE1-CG1 4.21Å; F354-I388 HydrophobicContact CZ-CG2 3.99Å
355	V	93.6	Very high	94.1	Very high	57 Å²	57	36.7 Å²	36.7	35%	0.345	19%	0.19	S	C	.	.	H	α-helix	trans	-60.8	-42.1	174.1	169.8	0	0	0	0	111.4	L206 L351 V352 F353	L206-V355 HydrophobicContact CB-CG1 4.46Å; L206-V355 HydrophobicContact CB-CG2 4.42Å; L206-V355 HydrophobicContact CD1-CG2 4.42Å; L351-V355 WeakPolarHBondContact O-CG2 3.21Å; L351-V355 PolarHBondContact O-N 2.95Å; V352-V355 PolarHBondContact O-N 3.12Å; F353-V355 VanDerWaalsContact C-N 3.34Å; F353-V355 PolarHBondContact O-N 3.45Å
356	N	93.8	Very high	94.1	Very high	25 Å²	25	32.2 Å²	32.2	13%	0.134	17%	0.173	C	C	.	.	H	α-helix	trans	-73.5	-48.4	-178.7	-78.6	-78.9	0	0	0	112.3	Y124 W128 V352 F353 F354	Y124-N356 PolarHBondContact OH-OD1 3.29Å; W128-N356 HydrophobicContact CD2-CB 3.75Å; W128-N356 HydrophobicContact CE3-CB 4.25Å; W128-N356 HydrophobicContact CG-CB 4.04Å; W128-N356 HydrophobicContact CZ2-CB 4.05Å; W128-N356 WeakPolarHBondContact CZ2-ND2 3.33Å; V352-N356 PolarHBondContact O-N 3.48Å; V352-N356 PolarHBondContact O-ND2 2.93Å; F353-N356 PolarHBondContact O-N 2.91Å; F353-N356 VanDerWaalsContact O-N 3.1Å; F354-N356 VanDerWaalsContact C-N 3.32Å; F354-N356 PolarHBondContact O-N 3.42Å
357	V	96.5	Very high	93.9	Very high	0 Å²	0	31.5 Å²	31.5	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-78.3	-32.5	-174.7	-58.9	0	0	0	0	112.7	W128 S132 F353 G359 V360 A361 Q381 V385	W128-V357 HydrophobicContact CB-CG1 4.21Å; W128-V357 HydrophobicContact CE3-CG1 4.33Å; S132-V357 WeakPolarHBondContact OG-CG1 3.43Å; F353-V357 HydrophobicContact CD1-CG2 4.11Å; F353-V357 HydrophobicContact CD2-CG1 4.11Å; F353-V357 HydrophobicContact CE1-CG2 3.77Å; F353-V357 HydrophobicContact CE2-CG1 3.76Å; F353-V357 HydrophobicContact CE2-CG2 4.5Å; F353-V357 HydrophobicContact CZ-CG1 3.97Å; F353-V357 HydrophobicContact CZ-CG2 3.98Å; F353-V357 WeakPolarHBondContact O-CG2 3.28Å; F353-V357 PolarHBondContact O-N 3.28Å; V357-G359 PolarHBondContact O-N 3.39Å; V357-V360 PolarHBondContact O-N 3.38Å; V357-A361 WeakPolarHBondContact O-CB 3.15Å; V357-A361 PolarHBondContact O-N 2.99Å; V357-Q381 HydrophobicContact CB-CG 4.24Å; V357-Q381 VanDerWaalsContact CB-NE2 3.32Å; V357-V385 HydrophobicContact CB-CG2 4.15Å; V357-V385 HydrophobicContact CG2-CG2 3.67Å
358	G	95.3	Very high	93.8	Very high	7 Å²	7	33.7 Å²	33.7	7%	0.072	18%	0.178	C	C	.	.	H	α-helix	trans	-68.8	-34.4	-176.7	0	0	0	0	0	112	M210 F354 V360 A361 M362	M210-G358 WeakPolarHBondContact SD-CA 3.29Å; F354-G358 WeakPolarHBondContact O-CA 3.36Å; F354-G358 PolarHBondContact O-N 2.94Å; G358-V360 VanDerWaalsContact C-N 3.34Å; G358-V360 PolarHBondContact O-N 3.35Å; G358-A361 PolarHBondContact O-N 2.94Å; G358-M362 WeakPolarHBondContact O-CB 3.32Å; G358-M362 VanDerWaalsContact O-CG 3.25Å; G358-M362 WeakPolarHBondContact O-CG 3.42Å; G358-M362 PolarHBondContact O-N 3.31Å
359	G	93.3	Very high	93.7	Very high	8 Å²	8	29.2 Å²	29.2	8%	0.082	15%	0.154	C	C	.	.	H	α-helix	trans	-59.8	-43.5	173.2	0	0	0	0	0	112.7	F117 M210 V357 R363	F117-G359 VanDerWaalsContact CZ-O 3.27Å; F117-G359 WeakPolarHBondContact CZ-O 3.37Å; M210-G359 PolarHBondContact SD-N 3.43Å; M210-G359 VanDerWaalsContact SD-N 3.4Å; V357-G359 PolarHBondContact O-N 3.39Å; G359-R363 PolarHBondContact O-N 2.92Å
360	V	95.3	Very high	93.2	Very high	11 Å²	11	26.3 Å²	26.3	7%	0.067	14%	0.139	C	C	.	.	H	α-helix	trans	-67.3	-47.5	176.2	179	0	0	0	0	110.2	P116 F117 W125 V357 G358 M362 R363 E364 Q381	P116-V360 HydrophobicContact CG-CG1 3.97Å; F117-V360 HydrophobicContact CD2-CB 4.43Å; F117-V360 HydrophobicContact CD2-CG2 3.41Å; F117-V360 VanDerWaalsContact CD2-CG2 3.41Å; F117-V360 HydrophobicContact CE2-CB 4.37Å; F117-V360 HydrophobicContact CE2-CG2 3.66Å; F117-V360 HydrophobicContact CG-CG2 4.13Å; W125-V360 HydrophobicContact CD2-CG2 4.33Å; W125-V360 HydrophobicContact CE3-CG2 3.59Å; W125-V360 HydrophobicContact CZ3-CG2 3.91Å; V357-V360 PolarHBondContact O-N 3.38Å; G358-V360 VanDerWaalsContact C-N 3.34Å; G358-V360 PolarHBondContact O-N 3.35Å; V360-M362 PolarHBondContact O-N 3.27Å; V360-R363 WeakPolarHBondContact O-CB 3.36Å; V360-R363 PolarHBondContact O-N 3.43Å; V360-R363 VanDerWaalsContact O-N 3.16Å; V360-E364 HydrophobicContact CG1-CG 4.46Å; V360-E364 WeakPolarHBondContact O-CG 3.3Å; V360-E364 PolarHBondContact O-N 3.35Å; V360-Q381 HydrophobicContact CB-CB 4.35Å; V360-Q381 HydrophobicContact CB-CG 3.97Å; V360-Q381 HydrophobicContact CG1-CB 3.73Å; V360-Q381 HydrophobicContact CG1-CG 3.87Å
361	A	96.4	Very high	92.5	Very high	4 Å²	4	26.8 Å²	26.8	3%	0.033	14%	0.143	C	C	.	.	H	α-helix	trans	-57.7	-45.9	178.4	0	0	0	0	0	112.2	V357 G358 R363 E364 I365 Q381 A382 V385	V357-A361 WeakPolarHBondContact O-CB 3.15Å; V357-A361 PolarHBondContact O-N 2.99Å; G358-A361 PolarHBondContact O-N 2.94Å; A361-R363 VanDerWaalsContact C-N 3.3Å; A361-R363 PolarHBondContact O-N 2.86Å; A361-E364 PolarHBondContact O-N 3.44Å; A361-I365 VanDerWaalsContact O-CG1 3.24Å; A361-I365 WeakPolarHBondContact O-CG1 3.48Å; A361-I365 PolarHBondContact O-N 3.44Å; A361-Q381 HydrophobicContact CB-CG 4.45Å; A361-A382 HydrophobicContact CB-CB 4.1Å; A361-V385 HydrophobicContact CB-CB 4.34Å; A361-V385 HydrophobicContact CB-CG2 4.03Å
362	M	94.3	Very high	91.5	Very high	9 Å²	9	28.7 Å²	28.7	4%	0.044	16%	0.161	C	C	.	.	H	α-helix	trans	-61	-39.6	177.5	-74.9	-57.6	-71.9	0	0	112	M210 I211 M216 F303 W305 I320 G358 V360 I365 Y366	M210-M362 HydrophobicContact CG-CG 3.98Å; I211-M362 HydrophobicContact CG2-CE 4.48Å; M216-M362 HydrophobicContact CE-CE 4.35Å; F303-M362 HydrophobicContact CE2-CB 4.34Å; W305-M362 HydrophobicContact CH2-CE 3.63Å; W305-M362 HydrophobicContact CZ2-CE 3.44Å; W305-M362 VanDerWaalsContact CZ2-CE 3.44Å; I320-M362 HydrophobicContact CG2-CE 3.84Å; I320-M362 HydrophobicContact CG2-SD 3.79Å; G358-M362 WeakPolarHBondContact O-CB 3.32Å; G358-M362 VanDerWaalsContact O-CG 3.25Å; G358-M362 WeakPolarHBondContact O-CG 3.42Å; G358-M362 PolarHBondContact O-N 3.31Å; V360-M362 PolarHBondContact O-N 3.27Å; M362-I365 HydrophobicContact SD-CD1 4.43Å; M362-Y366 WeakPolarHBondContact O-CB 3.27Å; M362-Y366 PolarHBondContact O-N 2.87Å
363	R	93.1	Very high	90.8	Very high	25 Å²	25	32.6 Å²	32.6	9%	0.094	17%	0.173	C	C	.	.	H	α-helix	trans	-65.2	-43.8	175	-179.5	60.5	179.9	131.6	10.9	112	P116 F117 F303 G359 V360 A361 Y366 D367	P116-R363 HydrophobicContact CB-CB 4.49Å; P116-R363 HydrophobicContact CB-CG 3.62Å; P116-R363 HydrophobicContact CG-CB 4.2Å; P116-R363 HydrophobicContact CG-CG 3.87Å; F117-R363 HydrophobicContact CE1-CB 3.82Å; F117-R363 HydrophobicContact CE1-CG 3.91Å; F117-R363 HydrophobicContact CZ-CB 4.17Å; F303-R363 HydrophobicContact CZ-CB 4.3Å; G359-R363 PolarHBondContact O-N 2.92Å; V360-R363 WeakPolarHBondContact O-CB 3.36Å; V360-R363 PolarHBondContact O-N 3.43Å; V360-R363 VanDerWaalsContact O-N 3.16Å; A361-R363 VanDerWaalsContact C-N 3.3Å; A361-R363 PolarHBondContact O-N 2.86Å; R363-Y366 PolarHBondContact O-N 3.22Å; R363-D367 VanDerWaalsContact CZ-CG 3.43Å; R363-D367 IonicContact CZ-OD1 3.57Å; R363-D367 IonicContact CZ-OD2 2.66Å; R363-D367 IonicContact NE-OD2 2.65Å; R363-D367 PolarHBondContact NE-OD2 3.45Å; R363-D367 VanDerWaalsContact NH1-CG 3.29Å; R363-D367 IonicContact NH1-OD1 3.21Å; R363-D367 PolarHBondContact NH1-OD1 2.98Å; R363-D367 IonicContact NH1-OD2 3.12Å; R363-D367 PolarHBondContact NH1-OD2 3.2Å; R363-D367 IonicContact NH2-OD1 3.69Å; R363-D367 PolarHBondContact NH2-OD1 2.98Å; R363-D367 VanDerWaalsContact NH2-OD1 3.16Å; R363-D367 IonicContact NH2-OD2 2.96Å; R363-D367 PolarHBondContact NH2-OD2 2.99Å; R363-D367 VanDerWaalsContact NH2-OD2 3.15Å; R363-D367 PolarHBondContact O-N 2.96Å
364	E	94.3	Very high	89.1	Confident	18 Å²	18	37.3 Å²	37.3	8%	0.084	20%	0.204	C	C	.	.	H	α-helix	trans	-64	-41.2	177.1	-71	-178.6	165.1	0	0	112.3	P116 V360 A361 D367 F368 G379 P380 Q381 A382	P116-E364 HydrophobicContact CG-CG 3.93Å; V360-E364 HydrophobicContact CG1-CG 4.46Å; V360-E364 WeakPolarHBondContact O-CG 3.3Å; V360-E364 PolarHBondContact O-N 3.35Å; A361-E364 PolarHBondContact O-N 3.44Å; E364-D367 PolarHBondContact O-N 3.49Å; E364-F368 VanDerWaalsContact O-CB 3.31Å; E364-F368 WeakPolarHBondContact O-CB 3.45Å; E364-F368 PolarHBondContact O-N 3.2Å; E364-G379 WeakPolarHBondContact OE2-CA 3.46Å; E364-P380 WeakPolarHBondContact OE1-CD 3.48Å; E364-Q381 WeakPolarHBondContact OE2-CA 3.32Å; E364-Q381 VanDerWaalsContact OE2-CB 3.31Å; E364-Q381 WeakPolarHBondContact OE2-CB 3.2Å; E364-Q381 PolarHBondContact OE2-N 2.75Å; E364-A382 HydrophobicContact CB-CB 4.11Å; E364-A382 PolarHBondContact OE2-N 3.47Å
365	I	93.4	Very high	87.9	Confident	35 Å²	35	44.1 Å²	44.1	18%	0.179	24%	0.236	C	C	.	.	H	α-helix	trans	-62.5	-46.4	175.2	-68.3	163.7	0	0	0	109.9	W305 I320 A361 M362 D367 F368 M369 L378 A382	W305-I365 HydrophobicContact CH2-CG2 4.38Å; W305-I365 HydrophobicContact CZ3-CG2 4.22Å; I320-I365 HydrophobicContact CD1-CG2 3.62Å; I320-I365 HydrophobicContact CG1-CG2 4.1Å; A361-I365 VanDerWaalsContact O-CG1 3.24Å; A361-I365 WeakPolarHBondContact O-CG1 3.48Å; A361-I365 PolarHBondContact O-N 3.44Å; M362-I365 HydrophobicContact SD-CD1 4.43Å; I365-D367 PolarHBondContact O-N 3.24Å; I365-F368 WeakPolarHBondContact O-CB 3.36Å; I365-F368 PolarHBondContact O-N 3.26Å; I365-F368 VanDerWaalsContact O-N 3.17Å; I365-M369 HydrophobicContact CG2-SD 4.44Å; I365-M369 WeakPolarHBondContact O-CG 3.36Å; I365-M369 PolarHBondContact O-N 3.47Å; I365-L378 HydrophobicContact CG1-CD1 4.21Å; I365-A382 HydrophobicContact CD1-CB 4.18Å; I365-A382 HydrophobicContact CG1-CB 3.72Å
366	Y	91.5	Very high	87.3	Confident	4 Å²	4	45.1 Å²	45.1	2%	0.016	24%	0.236	C	C	.	.	H	α-helix	trans	-57.5	-48.8	176.9	-175.4	-88.3	0	0	0	111.4	F303 E304 W305 M362 R363 F368 M369 D370	F303-Y366 HydrophobicContact CB-CD2 3.85Å; F303-Y366 HydrophobicContact CB-CE2 3.83Å; F303-Y366 HydrophobicContact CD1-CD1 4.07Å; F303-Y366 AromaticContact CD1-CD2 3.83Å; F303-Y366 HydrophobicContact CD1-CD2 3.83Å; F303-Y366 HydrophobicContact CD1-CE1 4.38Å; F303-Y366 HydrophobicContact CD1-CE2 4.18Å; F303-Y366 AromaticContact CD1-CG 3.78Å; F303-Y366 HydrophobicContact CD1-CG 3.78Å; F303-Y366 HydrophobicContact CE1-CD1 4.32Å; F303-Y366 HydrophobicContact CE1-CG 4.1Å; F303-Y366 AromaticContact CG-CD2 3.84Å; F303-Y366 HydrophobicContact CG-CD2 3.84Å; F303-Y366 HydrophobicContact CG-CE2 4.23Å; F303-Y366 HydrophobicContact CG-CG 4.19Å; E304-Y366 VanDerWaalsContact N-CE2 3.32Å; E304-Y366 PolarHBondContact N-OH 3.19Å; W305-Y366 HydrophobicContact CD2-CD2 4.46Å; W305-Y366 HydrophobicContact CH2-CD2 4.24Å; W305-Y366 HydrophobicContact CZ2-CD2 4.17Å; W305-Y366 HydrophobicContact CZ3-CD2 4.48Å; M362-Y366 WeakPolarHBondContact O-CB 3.27Å; M362-Y366 PolarHBondContact O-N 2.87Å; R363-Y366 PolarHBondContact O-N 3.22Å; Y366-F368 VanDerWaalsContact C-N 3.28Å; Y366-F368 PolarHBondContact O-N 2.73Å; Y366-M369 PolarHBondContact O-N 3.26Å; Y366-D370 HydrophobicContact CE1-CB 4.4Å; Y366-D370 WeakPolarHBondContact CE1-OD2 3.35Å; Y366-D370 WeakPolarHBondContact O-CB 3.31Å; Y366-D370 PolarHBondContact O-N 2.81Å; Y366-D370 PolarHBondContact OH-OD2 3.36Å
367	D	89.7	Confident	87	Confident	28 Å²	28	52.8 Å²	52.8	15%	0.15	27%	0.268	C	S	.	.	H	α-helix	trans	-68.2	-25	178.2	-76.1	-30.6	0	0	0	113.8	R45 R363 E364 I365 D371 K376	R45-D367 IonicContact NH1-OD1 3.25Å; R45-D367 PolarHBondContact NH1-OD1 3.12Å; R363-D367 VanDerWaalsContact CZ-CG 3.43Å; R363-D367 IonicContact CZ-OD1 3.57Å; R363-D367 IonicContact CZ-OD2 2.66Å; R363-D367 IonicContact NE-OD2 2.65Å; R363-D367 PolarHBondContact NE-OD2 3.45Å; R363-D367 VanDerWaalsContact NH1-CG 3.29Å; R363-D367 IonicContact NH1-OD1 3.21Å; R363-D367 PolarHBondContact NH1-OD1 2.98Å; R363-D367 IonicContact NH1-OD2 3.12Å; R363-D367 PolarHBondContact NH1-OD2 3.2Å; R363-D367 IonicContact NH2-OD1 3.69Å; R363-D367 PolarHBondContact NH2-OD1 2.98Å; R363-D367 VanDerWaalsContact NH2-OD1 3.16Å; R363-D367 IonicContact NH2-OD2 2.96Å; R363-D367 PolarHBondContact NH2-OD2 2.99Å; R363-D367 VanDerWaalsContact NH2-OD2 3.15Å; R363-D367 PolarHBondContact O-N 2.96Å; E364-D367 PolarHBondContact O-N 3.49Å; I365-D367 PolarHBondContact O-N 3.24Å; D367-D371 WeakPolarHBondContact O-CB 3.37Å; D367-K376 PolarHBondContact O-NZ 3.3Å
368	F	90.6	Very high	86.8	Confident	61 Å²	61	55.8 Å²	55.8	27%	0.268	28%	0.284	S	S	.	.	H	α-helix	trans	-72	-36.8	172.8	171.3	-98.1	0	0	0	112	E364 I365 Y366 K376 L378	E364-F368 VanDerWaalsContact O-CB 3.31Å; E364-F368 WeakPolarHBondContact O-CB 3.45Å; E364-F368 PolarHBondContact O-N 3.2Å; I365-F368 WeakPolarHBondContact O-CB 3.36Å; I365-F368 PolarHBondContact O-N 3.26Å; I365-F368 VanDerWaalsContact O-N 3.17Å; Y366-F368 VanDerWaalsContact C-N 3.28Å; Y366-F368 PolarHBondContact O-N 2.73Å; F368-K376 HydrophobicContact CD2-CB 4.42Å; F368-K376 HydrophobicContact CD2-CG 4.42Å; F368-K376 VanDerWaalsContact CE2-O 3.26Å; F368-K376 WeakPolarHBondContact CE2-O 3.36Å; F368-L378 HydrophobicContact CB-CD1 4.35Å; F368-L378 HydrophobicContact CD1-CD1 4.36Å; F368-L378 HydrophobicContact CG-CD1 4.2Å
369	M	87.8	Confident	86.7	Confident	16 Å²	16	56.1 Å²	56.1	8%	0.079	29%	0.287	C	S	.	.	H	α-helix	trans	-81.8	-31.3	179.7	-66.9	-168.1	-41.1	0	0	114.2	W305 A316 I365 Y366 D371	W305-M369 HydrophobicContact CD2-CE 4.4Å; W305-M369 HydrophobicContact CE3-CE 3.23Å; W305-M369 HydrophobicContact CE3-SD 4.43Å; W305-M369 HydrophobicContact CH2-CE 4.27Å; W305-M369 HydrophobicContact CZ3-CE 3.12Å; W305-M369 HydrophobicContact CZ3-SD 4.18Å; A316-M369 HydrophobicContact CB-CG 4.44Å; A316-M369 HydrophobicContact CB-SD 3.41Å; A316-M369 WeakPolarHBondContact CB-SD 3.38Å; I365-M369 HydrophobicContact CG2-SD 4.44Å; I365-M369 WeakPolarHBondContact O-CG 3.36Å; I365-M369 PolarHBondContact O-N 3.47Å; Y366-M369 PolarHBondContact O-N 3.26Å; M369-D371 VanDerWaalsContact C-N 3.3Å
370	D	84.3	Confident	86.8	Confident	37 Å²	37	59.2 Å²	59.2	20%	0.198	31%	0.306	C	S	.	.	S	Bend	trans	-79.3	-12.8	178.2	-92.5	15.2	0	0	0	112.9	R313 Y366	R313-D370 IonicContact CZ-OD1 3.39Å; R313-D370 IonicContact NH1-OD1 3.9Å; R313-D370 PolarHBondContact NH1-OD1 3.39Å; R313-D370 IonicContact NH2-OD1 2.66Å; R313-D370 PolarHBondContact NH2-OD1 3.36Å; Y366-D370 HydrophobicContact CE1-CB 4.4Å; Y366-D370 WeakPolarHBondContact CE1-OD2 3.35Å; Y366-D370 WeakPolarHBondContact O-CB 3.31Å; Y366-D370 PolarHBondContact O-N 2.81Å; Y366-D370 PolarHBondContact OH-OD2 3.36Å
371	D	80.5	Confident	86.9	Confident	33 Å²	33	58.9 Å²	58.9	18%	0.176	30%	0.303	C	S	.	.			trans	-81.4	125.3	179.5	-154.8	-48.5	0	0	0	111.4	D367 M369 K373 K376	D367-D371 WeakPolarHBondContact O-CB 3.37Å; M369-D371 VanDerWaalsContact C-N 3.3Å; D371-K373 PolarHBondContact O-N 3.09Å; D371-K373 VanDerWaalsContact OD1-CB 3.26Å; D371-K373 WeakPolarHBondContact OD1-CB 3.42Å; D371-K373 VanDerWaalsContact OD1-CG 3.3Å; D371-K373 WeakPolarHBondContact OD1-CG 3.26Å; D371-K373 PolarHBondContact OD1-N 3.28Å; D371-K376 HydrophobicContact CB-CD 3.5Å; D371-K376 VanDerWaalsContact CB-CD 3.5Å; D371-K376 WeakPolarHBondContact OD2-CD 3.46Å; D371-K376 WeakPolarHBondContact OD2-CE 3.32Å; D371-K376 IonicContact OD2-NZ 3.72Å; D371-K376 PolarHBondContact OD2-NZ 3.07Å
372	P	72.1	Confident	86.9	Confident	124 Å²	124	59 Å²	59	81%	0.805	30%	0.304	S	S	*	.			trans	-70.7	-14.1	176.2	28.7	-35.1	0	0	0	113.1	P374	P372-P374 WeakPolarHBondContact O-CD 3.26Å
373	K	78	Confident	87	Confident	145 Å²	145	66.1 Å²	66.1	63%	0.63	33%	0.33	S	S	*	.			trans	-73.5	121.1	-176.5	-66.2	176.7	-177.9	-179.8	0	111.2	D371 H375 K376	D371-K373 PolarHBondContact O-N 3.09Å; D371-K373 VanDerWaalsContact OD1-CB 3.26Å; D371-K373 WeakPolarHBondContact OD1-CB 3.42Å; D371-K373 VanDerWaalsContact OD1-CG 3.3Å; D371-K373 WeakPolarHBondContact OD1-CG 3.26Å; D371-K373 PolarHBondContact OD1-N 3.28Å; K373-H375 VanDerWaalsContact C-N 3.26Å; K373-H375 PolarHBondContact O-N 3.45Å; K373-K376 PolarHBondContact O-N 2.85Å
374	P	62.2	Low	87.3	Confident	109 Å²	109	65.6 Å²	65.6	71%	0.708	33%	0.329	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.2	-19.3	-174.2	25.4	-33.5	0	0	0	114.5	P372	P372-P374 WeakPolarHBondContact O-CD 3.26Å
375	H	70.1	Confident	87.4	Confident	171 Å²	171	65.5 Å²	65.5	79%	0.792	33%	0.33	S	S	*	.	T	Hydrogen-bonded Turn	trans	-105.6	14.8	-174.8	-52.6	-60.9	0	0	0	114.4	K373 K377	K373-H375 VanDerWaalsContact C-N 3.26Å; K373-H375 PolarHBondContact O-N 3.45Å; H375-K377 PolarHBondContact O-N 2.92Å
376	K	81.1	Confident	87.6	Confident	78 Å²	78	66 Å²	66	34%	0.339	34%	0.339	S	S	.	.	P	Polyproline II helix	trans	-63.5	137.3	175.7	-169.4	166.5	-174	174.2	0	109.3	D367 F368 D371 K373	D367-K376 PolarHBondContact O-NZ 3.3Å; F368-K376 HydrophobicContact CD2-CB 4.42Å; F368-K376 HydrophobicContact CD2-CG 4.42Å; F368-K376 VanDerWaalsContact CE2-O 3.26Å; F368-K376 WeakPolarHBondContact CE2-O 3.36Å; D371-K376 HydrophobicContact CB-CD 3.5Å; D371-K376 VanDerWaalsContact CB-CD 3.5Å; D371-K376 WeakPolarHBondContact OD2-CD 3.46Å; D371-K376 WeakPolarHBondContact OD2-CE 3.32Å; D371-K376 IonicContact OD2-NZ 3.72Å; D371-K376 PolarHBondContact OD2-NZ 3.07Å; K373-K376 PolarHBondContact O-N 2.85Å
377	K	88.4	Confident	88	Confident	185 Å²	185	66.7 Å²	66.7	80%	0.804	35%	0.346	S	S	*	.	P	Polyproline II helix	trans	-82.2	147.3	173.8	-64.4	-176.6	178.9	-176.5	0	109.4	H375	H375-K377 PolarHBondContact O-N 2.92Å
378	L	91.5	Very high	88.4	Confident	64 Å²	64	65.4 Å²	65.4	34%	0.335	34%	0.339	S	S	.	.	P	Polyproline II helix	trans	-59.2	142.6	166.8	-174.2	63.6	0	0	0	108.7	I365 F368 A382 W383	I365-L378 HydrophobicContact CG1-CD1 4.21Å; F368-L378 HydrophobicContact CB-CD1 4.35Å; F368-L378 HydrophobicContact CD1-CD1 4.36Å; F368-L378 HydrophobicContact CG-CD1 4.2Å; L378-A382 HydrophobicContact CD1-CB 3.87Å; L378-A382 HydrophobicContact CD2-CB 4.24Å; L378-A382 HydrophobicContact CG-CB 3.93Å; L378-W383 HydrophobicContact CD2-CB 4.14Å
379	G	93.4	Very high	88.8	Confident	13 Å²	13	62.6 Å²	62.6	13%	0.134	33%	0.327	C	S	.	.	P	Polyproline II helix	trans	-61.1	149.7	177.7	0	0	0	0	0	111.9	E364 Q381 A382 W383	E364-G379 WeakPolarHBondContact OE2-CA 3.46Å; G379-Q381 VanDerWaalsContact C-N 3.29Å; G379-Q381 PolarHBondContact O-N 3.03Å; G379-A382 PolarHBondContact O-N 3.21Å; G379-W383 WeakPolarHBondContact O-CB 3.26Å; G379-W383 PolarHBondContact O-N 3.42Å
380	P	95.6	Very high	89.3	Confident	74 Å²	74	64 Å²	64	48%	0.481	34%	0.341	S	S	.	.	H	α-helix	trans	-62.2	-35.9	-174.3	25.7	-35.1	0	0	0	112.6	L129 E364 L384	L129-P380 HydrophobicContact CD1-CB 4.19Å; E364-P380 WeakPolarHBondContact OE1-CD 3.48Å; P380-L384 WeakPolarHBondContact O-CB 3.31Å; P380-L384 WeakPolarHBondContact O-CG 3.47Å; P380-L384 PolarHBondContact O-N 2.94Å
381	Q	96.9	Very high	90	Very high	4 Å²	4	63 Å²	63	2%	0.019	34%	0.336	C	S	.	.	H	α-helix	trans	-72.7	-44.2	-179.5	-165.4	64.6	48.4	0	0	111.3	S132 V357 V360 A361 E364 G379 W383 L384 V385	S132-Q381 PolarHBondContact OG-NE2 3.11Å; V357-Q381 HydrophobicContact CB-CG 4.24Å; V357-Q381 VanDerWaalsContact CB-NE2 3.32Å; V360-Q381 HydrophobicContact CB-CB 4.35Å; V360-Q381 HydrophobicContact CB-CG 3.97Å; V360-Q381 HydrophobicContact CG1-CB 3.73Å; V360-Q381 HydrophobicContact CG1-CG 3.87Å; A361-Q381 HydrophobicContact CB-CG 4.45Å; E364-Q381 WeakPolarHBondContact OE2-CA 3.32Å; E364-Q381 VanDerWaalsContact OE2-CB 3.31Å; E364-Q381 WeakPolarHBondContact OE2-CB 3.2Å; E364-Q381 PolarHBondContact OE2-N 2.75Å; G379-Q381 VanDerWaalsContact C-N 3.29Å; G379-Q381 PolarHBondContact O-N 3.03Å; Q381-W383 VanDerWaalsContact C-N 3.29Å; Q381-W383 PolarHBondContact O-N 3.22Å; Q381-L384 PolarHBondContact O-N 3.24Å; Q381-V385 WeakPolarHBondContact O-CG2 3.45Å; Q381-V385 PolarHBondContact O-N 2.92Å
382	A	96.8	Very high	90.8	Very high	5 Å²	5	61.4 Å²	61.4	4%	0.041	33%	0.328	C	S	.	.	H	α-helix	trans	-60.3	-40.6	175.3	0	0	0	0	0	111.9	A361 E364 I365 L378 G379 A386	A361-A382 HydrophobicContact CB-CB 4.1Å; E364-A382 HydrophobicContact CB-CB 4.11Å; E364-A382 PolarHBondContact OE2-N 3.47Å; I365-A382 HydrophobicContact CD1-CB 4.18Å; I365-A382 HydrophobicContact CG1-CB 3.72Å; L378-A382 HydrophobicContact CD1-CB 3.87Å; L378-A382 HydrophobicContact CD2-CB 4.24Å; L378-A382 HydrophobicContact CG-CB 3.93Å; G379-A382 PolarHBondContact O-N 3.21Å; A382-A386 PolarHBondContact O-N 3.19Å; A382-A386 VanDerWaalsContact O-N 3.12Å
383	W	96.8	Very high	92	Very high	159 Å²	159	58.4 Å²	58.4	60%	0.602	31%	0.305	S	S	*	.	H	α-helix	trans	-63	-46.7	175	-172.5	92.2	0	0	0	111.8	L378 G379 Q381 A386 A387	L378-W383 HydrophobicContact CD2-CB 4.14Å; G379-W383 WeakPolarHBondContact O-CB 3.26Å; G379-W383 PolarHBondContact O-N 3.42Å; Q381-W383 VanDerWaalsContact C-N 3.29Å; Q381-W383 PolarHBondContact O-N 3.22Å; W383-A386 PolarHBondContact O-N 3.19Å; W383-A387 HydrophobicContact CE3-CB 4.4Å; W383-A387 HydrophobicContact CH2-CB 4.33Å; W383-A387 HydrophobicContact CZ3-CB 4.09Å; W383-A387 PolarHBondContact O-N 2.87Å
384	L	97.6	Very high	93	Very high	15 Å²	15	56.1 Å²	56.1	8%	0.079	30%	0.299	C	S	.	.	H	α-helix	trans	-63.8	-41.7	178	-81	166.4	0	0	0	112.5	L129 V133 P380 Q381 A386 A387 I388	L129-L384 HydrophobicContact CD1-CD1 3.56Å; V133-L384 HydrophobicContact CG2-CD1 3.72Å; V133-L384 HydrophobicContact CG2-CD2 4.21Å; P380-L384 WeakPolarHBondContact O-CB 3.31Å; P380-L384 WeakPolarHBondContact O-CG 3.47Å; P380-L384 PolarHBondContact O-N 2.94Å; Q381-L384 PolarHBondContact O-N 3.24Å; L384-A386 VanDerWaalsContact C-N 3.3Å; L384-A386 PolarHBondContact O-N 3.49Å; L384-A387 PolarHBondContact O-N 3.23Å; L384-I388 WeakPolarHBondContact O-CB 3.34Å; L384-I388 WeakPolarHBondContact O-CD1 3.35Å; L384-I388 VanDerWaalsContact O-CG1 3.23Å; L384-I388 WeakPolarHBondContact O-CG1 3.36Å; L384-I388 PolarHBondContact O-N 2.96Å
385	V	97.9	Very high	94.7	Very high	16 Å²	16	51 Å²	51	10%	0.097	27%	0.265	C	S	.	.	H	α-helix	trans	-61.1	-41	176.8	168.3	0	0	0	0	111.1	F354 V357 A361 Q381 T389	F354-V385 HydrophobicContact CE1-CG1 4.21Å; V357-V385 HydrophobicContact CB-CG2 4.15Å; V357-V385 HydrophobicContact CG2-CG2 3.67Å; A361-V385 HydrophobicContact CB-CB 4.34Å; A361-V385 HydrophobicContact CB-CG2 4.03Å; Q381-V385 WeakPolarHBondContact O-CG2 3.45Å; Q381-V385 PolarHBondContact O-N 2.92Å; V385-T389 WeakPolarHBondContact O-CB 3.21Å; V385-T389 PolarHBondContact O-N 2.79Å; V385-T389 PolarHBondContact O-OG1 2.86Å
386	A	97.7	Very high	95.9	Very high	45 Å²	45	43 Å²	43	37%	0.372	23%	0.228	S	C	.	.	H	α-helix	trans	-65	-43.4	175.2	0	0	0	0	0	112	A382 W383 L384 T389 A390	A382-A386 PolarHBondContact O-N 3.19Å; A382-A386 VanDerWaalsContact O-N 3.12Å; W383-A386 PolarHBondContact O-N 3.19Å; L384-A386 VanDerWaalsContact C-N 3.3Å; L384-A386 PolarHBondContact O-N 3.49Å; A386-T389 PolarHBondContact O-N 3.43Å; A386-A390 WeakPolarHBondContact O-CB 3.3Å; A386-A390 PolarHBondContact O-N 3.02Å
387	A	98.3	Very high	96.7	Very high	19 Å²	19	42.7 Å²	42.7	16%	0.157	23%	0.233	C	C	.	.	H	α-helix	trans	-61.2	-50.3	176.3	0	0	0	0	0	111.6	W383 L384 T389 A390 T391	W383-A387 HydrophobicContact CE3-CB 4.4Å; W383-A387 HydrophobicContact CH2-CB 4.33Å; W383-A387 HydrophobicContact CZ3-CB 4.09Å; W383-A387 PolarHBondContact O-N 2.87Å; L384-A387 PolarHBondContact O-N 3.23Å; A387-T389 VanDerWaalsContact C-N 3.35Å; A387-T389 PolarHBondContact O-N 3.36Å; A387-A390 WeakPolarHBondContact O-CB 3.45Å; A387-A390 PolarHBondContact O-N 3.44Å; A387-A390 VanDerWaalsContact O-N 3.12Å; A387-T391 PolarHBondContact O-N 3.19Å; A387-T391 PolarHBondContact O-OG1 2.91Å; A387-T391 VanDerWaalsContact O-OG1 3.09Å
388	I	98.6	Very high	97	Very high	0 Å²	0	38.3 Å²	38.3	0%	0	21%	0.214	C	C	.	.	H	α-helix	trans	-54.2	-51.3	176	-72.6	161.9	0	0	0	110.8	Y135 E136 L139 F353 F354 L384 A390 T391 E392	Y135-I388 HydrophobicContact CD1-CD1 4.02Å; Y135-I388 HydrophobicContact CD1-CG1 4.21Å; Y135-I388 HydrophobicContact CD1-CG2 3.8Å; Y135-I388 HydrophobicContact CE1-CG2 3.5Å; E136-I388 HydrophobicContact CB-CG1 4Å; E136-I388 WeakPolarHBondContact OE2-CA 3.42Å; E136-I388 WeakPolarHBondContact OE2-CG1 3.47Å; E136-I388 PolarHBondContact OE2-N 3.18Å; L139-I388 HydrophobicContact CD1-CB 4.42Å; L139-I388 HydrophobicContact CD1-CG1 4.47Å; L139-I388 HydrophobicContact CD1-CG2 3.84Å; F353-I388 HydrophobicContact CE1-CD1 4.1Å; F353-I388 HydrophobicContact CZ-CD1 3.72Å; F354-I388 HydrophobicContact CZ-CG2 3.99Å; L384-I388 WeakPolarHBondContact O-CB 3.34Å; L384-I388 WeakPolarHBondContact O-CD1 3.35Å; L384-I388 VanDerWaalsContact O-CG1 3.23Å; L384-I388 WeakPolarHBondContact O-CG1 3.36Å; L384-I388 PolarHBondContact O-N 2.96Å; I388-A390 VanDerWaalsContact C-N 3.26Å; I388-A390 PolarHBondContact O-N 3.42Å; I388-T391 PolarHBondContact O-N 3.22Å; I388-E392 HydrophobicContact CG2-CG 4.29Å; I388-E392 WeakPolarHBondContact O-CB 3.49Å; I388-E392 VanDerWaalsContact O-CG 3.23Å; I388-E392 WeakPolarHBondContact O-CG 3.32Å; I388-E392 PolarHBondContact O-N 3.19Å
389	T	98.4	Very high	97.2	Very high	2 Å²	2	35.7 Å²	35.7	1%	0.012	20%	0.2	C	C	.	.	H	α-helix	trans	-60.9	-38	-178.5	-54.1	0	0	0	0	111.5	V323 L326 A327 N330 V385 A386 A387 L393	V323-T389 HydrophobicContact CG1-CG2 4.35Å; L326-T389 HydrophobicContact CB-CG2 3.97Å; L326-T389 HydrophobicContact CD2-CG2 3.77Å; L326-T389 HydrophobicContact CG-CG2 3.66Å; A327-T389 HydrophobicContact CB-CG2 3.96Å; N330-T389 PolarHBondContact ND2-O 3.16Å; V385-T389 WeakPolarHBondContact O-CB 3.21Å; V385-T389 PolarHBondContact O-N 2.79Å; V385-T389 PolarHBondContact O-OG1 2.86Å; A386-T389 PolarHBondContact O-N 3.43Å; A387-T389 VanDerWaalsContact C-N 3.35Å; A387-T389 PolarHBondContact O-N 3.36Å; T389-L393 PolarHBondContact O-N 2.93Å
390	A	98.5	Very high	97.2	Very high	47 Å²	47	36.5 Å²	36.5	39%	0.388	20%	0.201	S	C	.	.	H	α-helix	trans	-69.8	-46	175.6	0	0	0	0	0	112.3	A386 A387 I388 E392 L393 L394	A386-A390 WeakPolarHBondContact O-CB 3.3Å; A386-A390 PolarHBondContact O-N 3.02Å; A387-A390 WeakPolarHBondContact O-CB 3.45Å; A387-A390 PolarHBondContact O-N 3.44Å; A387-A390 VanDerWaalsContact O-N 3.12Å; I388-A390 VanDerWaalsContact C-N 3.26Å; I388-A390 PolarHBondContact O-N 3.42Å; A390-E392 VanDerWaalsContact C-N 3.33Å; A390-E392 PolarHBondContact O-N 2.59Å; A390-L393 WeakPolarHBondContact O-CB 3.43Å; A390-L393 PolarHBondContact O-N 3.2Å; A390-L394 WeakPolarHBondContact O-CG 3.39Å; A390-L394 PolarHBondContact O-N 3.46Å
391	T	98.6	Very high	97.1	Very high	14 Å²	14	36.5 Å²	36.5	9%	0.086	20%	0.201	C	C	.	.	H	α-helix	trans	-62.7	-41	179	-59.4	0	0	0	0	111.1	E136 L139 I140 L143 A387 I388 L394 I395	E136-T391 PolarHBondContact OE1-OG1 3.16Å; L139-T391 HydrophobicContact CB-CG2 3.69Å; I140-T391 HydrophobicContact CG1-CG2 4.22Å; L143-T391 HydrophobicContact CD2-CG2 4.38Å; A387-T391 PolarHBondContact O-N 3.19Å; A387-T391 PolarHBondContact O-OG1 2.91Å; A387-T391 VanDerWaalsContact O-OG1 3.09Å; I388-T391 PolarHBondContact O-N 3.22Å; T391-L394 PolarHBondContact O-N 2.81Å; T391-I395 HydrophobicContact CG2-CD1 4.45Å; T391-I395 WeakPolarHBondContact O-CG1 3.4Å; T391-I395 PolarHBondContact O-N 3.31Å
392	E	98.1	Very high	96.9	Very high	0 Å²	0	42.5 Å²	42.5	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-59.2	-46.2	172.6	-74	-176.8	158.2	0	0	112.2	Y135 L139 N330 L334 R350 I388 A390 L394 I395 V396	Y135-E392 WeakPolarHBondContact CE1-OE1 3.35Å; Y135-E392 PolarHBondContact OH-OE1 3.43Å; L139-E392 HydrophobicContact CD1-CG 3.64Å; L139-E392 HydrophobicContact CD2-CG 4.06Å; N330-E392 HydrophobicContact CB-CB 4.16Å; N330-E392 WeakPolarHBondContact CB-OE2 3.19Å; N330-E392 WeakPolarHBondContact ND2-CB 3.38Å; N330-E392 PolarHBondContact ND2-OE2 3.24Å; L334-E392 HydrophobicContact CD1-CB 3.93Å; L334-E392 HydrophobicContact CD1-CG 3.65Å; R350-E392 IonicContact CZ-OE1 3.06Å; R350-E392 IonicContact CZ-OE2 3.15Å; R350-E392 IonicContact NE-OE1 3.38Å; R350-E392 PolarHBondContact NE-OE1 2.83Å; R350-E392 IonicContact NE-OE2 2.73Å; R350-E392 IonicContact NH2-OE1 3.15Å; R350-E392 PolarHBondContact NH2-OE1 2.97Å; R350-E392 IonicContact NH2-OE2 3.16Å; R350-E392 PolarHBondContact NH2-OE2 3.42Å; I388-E392 HydrophobicContact CG2-CG 4.29Å; I388-E392 WeakPolarHBondContact O-CB 3.49Å; I388-E392 VanDerWaalsContact O-CG 3.23Å; I388-E392 WeakPolarHBondContact O-CG 3.32Å; I388-E392 PolarHBondContact O-N 3.19Å; A390-E392 VanDerWaalsContact C-N 3.33Å; A390-E392 PolarHBondContact O-N 2.59Å; E392-L394 VanDerWaalsContact C-N 3.31Å; E392-L394 PolarHBondContact O-N 2.89Å; E392-I395 WeakPolarHBondContact O-CB 3.44Å; E392-I395 PolarHBondContact O-N 2.95Å; E392-V396 WeakPolarHBondContact O-CG2 3.35Å; E392-V396 PolarHBondContact O-N 2.84Å
393	L	97.6	Very high	96.6	Very high	62 Å²	62	43.1 Å²	43.1	33%	0.325	23%	0.232	S	C	.	.	H	α-helix	trans	-60.3	-42.7	175.4	173.5	61.7	0	0	0	111.1	L326 T389 A390 I395 V396 V397	L326-L393 HydrophobicContact CD1-CB 4.26Å; L326-L393 HydrophobicContact CD1-CD1 4.03Å; L326-L393 HydrophobicContact CD1-CD2 3.99Å; L326-L393 HydrophobicContact CD1-CG 4.3Å; L326-L393 HydrophobicContact CD2-CB 4.42Å; L326-L393 HydrophobicContact CD2-CD2 3.9Å; T389-L393 PolarHBondContact O-N 2.93Å; A390-L393 WeakPolarHBondContact O-CB 3.43Å; A390-L393 PolarHBondContact O-N 3.2Å; L393-I395 VanDerWaalsContact C-N 3.31Å; L393-I395 PolarHBondContact O-N 2.84Å; L393-V396 WeakPolarHBondContact O-CB 3.42Å; L393-V396 PolarHBondContact O-N 2.94Å; L393-V397 HydrophobicContact CD1-CG2 4.03Å; L393-V397 HydrophobicContact CG-CG2 4.35Å; L393-V397 VanDerWaalsContact O-CG2 3.32Å; L393-V397 WeakPolarHBondContact O-CG2 3.48Å; L393-V397 PolarHBondContact O-N 3.18Å
394	L	98.1	Very high	96.3	Very high	96 Å²	96	38 Å²	38	50%	0.503	22%	0.216	S	C	.	.	H	α-helix	trans	-62.3	-38.2	177.6	-69.1	174.4	0	0	0	112.2	L143 A390 T391 E392 V397 K398	L143-L394 HydrophobicContact CD1-CB 3.96Å; A390-L394 WeakPolarHBondContact O-CG 3.39Å; A390-L394 PolarHBondContact O-N 3.46Å; T391-L394 PolarHBondContact O-N 2.81Å; E392-L394 VanDerWaalsContact C-N 3.31Å; E392-L394 PolarHBondContact O-N 2.89Å; L394-V397 PolarHBondContact O-N 3.09Å; L394-K398 VanDerWaalsContact O-CB 3.3Å; L394-K398 WeakPolarHBondContact O-CB 3.49Å; L394-K398 PolarHBondContact O-N 3.16Å
395	I	97.9	Very high	95.9	Very high	1 Å²	1	42.6 Å²	42.6	1%	0.005	25%	0.245	C	C	.	.	H	α-helix	trans	-61.5	-48.7	173.5	-68.1	164.9	0	0	0	109.7	L139 I142 L143 L334 T391 E392 L393 V397 K398 Y399	L139-I395 HydrophobicContact CB-CD1 4.03Å; L139-I395 HydrophobicContact CD2-CD1 3.72Å; L139-I395 HydrophobicContact CG-CD1 4.47Å; L139-I395 WeakPolarHBondContact O-CD1 3.26Å; I142-I395 HydrophobicContact CB-CD1 4.41Å; I142-I395 HydrophobicContact CG2-CD1 4.14Å; I142-I395 HydrophobicContact CG2-CG2 4.26Å; L143-I395 HydrophobicContact CB-CD1 4.45Å; L143-I395 HydrophobicContact CB-CG1 3.86Å; L143-I395 HydrophobicContact CD1-CG1 3.83Å; L143-I395 HydrophobicContact CG-CG1 4.44Å; L334-I395 HydrophobicContact CD2-CB 4.3Å; L334-I395 HydrophobicContact CD2-CG2 3.99Å; T391-I395 HydrophobicContact CG2-CD1 4.45Å; T391-I395 WeakPolarHBondContact O-CG1 3.4Å; T391-I395 PolarHBondContact O-N 3.31Å; E392-I395 WeakPolarHBondContact O-CB 3.44Å; E392-I395 PolarHBondContact O-N 2.95Å; L393-I395 VanDerWaalsContact C-N 3.31Å; L393-I395 PolarHBondContact O-N 2.84Å; I395-V397 PolarHBondContact O-N 3.36Å; I395-K398 PolarHBondContact O-N 3.47Å; I395-Y399 HydrophobicContact CG2-CD1 3.84Å; I395-Y399 HydrophobicContact CG2-CE1 3.94Å; I395-Y399 HydrophobicContact CG2-CG 4.24Å; I395-Y399 VanDerWaalsContact O-CB 3.31Å; I395-Y399 WeakPolarHBondContact O-CB 3.37Å; I395-Y399 WeakPolarHBondContact O-CD1 3.32Å; I395-Y399 PolarHBondContact O-N 2.68Å
396	V	96.9	Very high	95.7	Very high	3 Å²	3	45 Å²	45	2%	0.018	26%	0.257	C	S	.	.	H	α-helix	trans	-57.5	-48.6	178.6	172.5	0	0	0	0	111.1	Y333 L334 V337 E392 L393 K398 Y399 D400 L404	Y333-V396 VanDerWaalsContact CB-CG1 3.47Å; Y333-V396 HydrophobicContact CD1-CG1 3.6Å; Y333-V396 HydrophobicContact CG-CG1 3.76Å; L334-V396 HydrophobicContact CD2-CG2 3.95Å; L334-V396 HydrophobicContact CG-CG2 4.09Å; V337-V396 HydrophobicContact CG1-CG1 4.5Å; E392-V396 WeakPolarHBondContact O-CG2 3.35Å; E392-V396 PolarHBondContact O-N 2.84Å; L393-V396 WeakPolarHBondContact O-CB 3.42Å; L393-V396 PolarHBondContact O-N 2.94Å; V396-K398 VanDerWaalsContact C-N 3.33Å; V396-K398 PolarHBondContact O-N 3.47Å; V396-Y399 PolarHBondContact O-N 3.1Å; V396-D400 PolarHBondContact O-N 3.48Å; V396-L404 HydrophobicContact CG1-CD1 4.14Å; V396-L404 HydrophobicContact CG1-CD2 4.42Å
397	V	96.3	Very high	95.3	Very high	72 Å²	72	47.9 Å²	47.9	44%	0.436	27%	0.274	S	S	.	.	H	α-helix	trans	-59.9	-42	177.9	173	0	0	0	0	112.3	L393 L394 I395 L404	L393-V397 HydrophobicContact CD1-CG2 4.03Å; L393-V397 HydrophobicContact CG-CG2 4.35Å; L393-V397 VanDerWaalsContact O-CG2 3.32Å; L393-V397 WeakPolarHBondContact O-CG2 3.48Å; L393-V397 PolarHBondContact O-N 3.18Å; L394-V397 PolarHBondContact O-N 3.09Å; I395-V397 PolarHBondContact O-N 3.36Å; V397-L404 VanDerWaalsContact CA-CD1 3.48Å; V397-L404 HydrophobicContact CB-CD1 4.18Å; V397-L404 HydrophobicContact CG2-CD1 3.82Å
398	K	96	Very high	94.9	Very high	94 Å²	94	50.1 Å²	50.1	41%	0.409	28%	0.283	S	S	.	.	H	α-helix	trans	-70.1	-40.4	179.3	-177.2	-171.6	-177.6	-167.2	0	112.2	L143 Q145 L394 I395 V396	L143-K398 HydrophobicContact CD1-CD 4.26Å; L143-K398 WeakPolarHBondContact O-CD 3.33Å; L143-K398 PolarHBondContact O-NZ 2.93Å; Q145-K398 PolarHBondContact O-NZ 3.27Å; L394-K398 VanDerWaalsContact O-CB 3.3Å; L394-K398 WeakPolarHBondContact O-CB 3.49Å; L394-K398 PolarHBondContact O-N 3.16Å; I395-K398 PolarHBondContact O-N 3.47Å; V396-K398 VanDerWaalsContact C-N 3.33Å; V396-K398 PolarHBondContact O-N 3.47Å
399	Y	95.5	Very high	94.6	Very high	9 Å²	9	51.7 Å²	51.7	4%	0.035	29%	0.294	C	S	.	.	H	α-helix	trans	-81.7	-28.9	-167.5	-85.3	52.3	0	0	0	113.6	I142 V147 L338 I395 V396	I142-Y399 WeakPolarHBondContact CG2-OH 3.27Å; I142-Y399 PolarHBondContact O-OH 2.84Å; V147-Y399 HydrophobicContact CB-CD2 4.18Å; V147-Y399 HydrophobicContact CB-CE2 4.5Å; V147-Y399 HydrophobicContact CG1-CD2 3.8Å; V147-Y399 HydrophobicContact CG1-CE2 4.41Å; V147-Y399 HydrophobicContact CG1-CG 4.31Å; V147-Y399 HydrophobicContact CG2-CD1 4.47Å; V147-Y399 HydrophobicContact CG2-CD2 4.25Å; V147-Y399 HydrophobicContact CG2-CG 4.08Å; L338-Y399 HydrophobicContact CD2-CD2 3.95Å; L338-Y399 HydrophobicContact CD2-CE2 3.58Å; I395-Y399 HydrophobicContact CG2-CD1 3.84Å; I395-Y399 HydrophobicContact CG2-CE1 3.94Å; I395-Y399 HydrophobicContact CG2-CG 4.24Å; I395-Y399 VanDerWaalsContact O-CB 3.31Å; I395-Y399 WeakPolarHBondContact O-CB 3.37Å; I395-Y399 WeakPolarHBondContact O-CD1 3.32Å; I395-Y399 PolarHBondContact O-N 2.68Å; V396-Y399 PolarHBondContact O-N 3.1Å
400	D	93.1	Very high	94.2	Very high	30 Å²	30	59 Å²	59	16%	0.16	33%	0.325	C	S	.	.			trans	-146.1	74.9	174.8	-168.5	2.8	0	0	0	112.4	F336 V337 V396 H402 T403	F336-D400 WeakPolarHBondContact CE1-OD2 3.38Å; V337-D400 HydrophobicContact CG1-CB 3.84Å; V396-D400 PolarHBondContact O-N 3.48Å; D400-H402 VanDerWaalsContact C-N 3.25Å; D400-H402 PolarHBondContact O-N 3.4Å; D400-H402 PolarHBondContact OD1-N 2.73Å; D400-T403 VanDerWaalsContact CG-OG1 3.23Å; D400-T403 PolarHBondContact OD1-N 2.88Å; D400-T403 PolarHBondContact OD1-OG1 3.46Å; D400-T403 WeakPolarHBondContact OD2-CB 3.18Å; D400-T403 PolarHBondContact OD2-OG1 3.44Å
401	P	92.9	Very high	93.8	Very high	73 Å²	73	63 Å²	63	47%	0.474	33%	0.331	S	S	.	.	H	α-helix	trans	-66.2	-29.5	178.4	26.7	-34.4	0	0	0	112.2	L404 T405	P401-L404 PolarHBondContact O-N 2.89Å; P401-T405 WeakPolarHBondContact O-CB 3.41Å; P401-T405 VanDerWaalsContact O-CG2 3.24Å; P401-T405 WeakPolarHBondContact O-CG2 3.33Å; P401-T405 PolarHBondContact O-N 3.33Å; P401-T405 PolarHBondContact O-OG1 2.95Å; P401-T405 VanDerWaalsContact O-OG1 3.05Å
402	H	93	Very high	93.5	Very high	131 Å²	131	62.8 Å²	62.8	61%	0.606	33%	0.329	S	S	*	.	H	α-helix	trans	-62.1	-53.3	-176.3	175.4	-88.5	0	0	0	111	D400 L404 T405 L406	D400-H402 VanDerWaalsContact C-N 3.25Å; D400-H402 PolarHBondContact O-N 3.4Å; D400-H402 PolarHBondContact OD1-N 2.73Å; H402-L404 VanDerWaalsContact C-N 3.26Å; H402-L404 PolarHBondContact O-N 3.14Å; H402-T405 PolarHBondContact O-N 3.4Å; H402-T405 VanDerWaalsContact O-N 3.1Å; H402-T405 PolarHBondContact O-OG1 3.1Å; H402-L406 PolarHBondContact O-N 2.93Å
403	T	91.5	Very high	93.2	Very high	17 Å²	17	65.1 Å²	65.1	10%	0.104	35%	0.346	C	S	.	.	H	α-helix	trans	-59.3	-37.4	179.6	-60.6	0	0	0	0	112.1	Q234 F336 D400 L406	Q234-T403 HydrophobicContact CB-CG2 3.85Å; Q234-T403 PolarHBondContact NE2-O 3.19Å; Q234-T403 VanDerWaalsContact O-CG2 3.3Å; Q234-T403 WeakPolarHBondContact O-CG2 3.47Å; F336-T403 HydrophobicContact CE1-CG2 4.28Å; D400-T403 VanDerWaalsContact CG-OG1 3.23Å; D400-T403 PolarHBondContact OD1-N 2.88Å; D400-T403 PolarHBondContact OD1-OG1 3.46Å; D400-T403 WeakPolarHBondContact OD2-CB 3.18Å; D400-T403 PolarHBondContact OD2-OG1 3.44Å; T403-L406 HydrophobicContact CG2-CD1 4.49Å; T403-L406 WeakPolarHBondContact O-CB 3.28Å; T403-L406 WeakPolarHBondContact O-CD1 3.4Å; T403-L406 WeakPolarHBondContact O-CG 3.43Å; T403-L406 PolarHBondContact O-N 3.31Å
404	L	89.3	Confident	93	Very high	53 Å²	53	67 Å²	67	28%	0.277	35%	0.353	S	S	.	.	H	α-helix	trans	-73.6	-27.7	177.7	-69.5	172.4	0	0	0	114.1	Y333 V396 V397 P401 H402 L406	Y333-L404 HydrophobicContact CD1-CD2 4.15Å; Y333-L404 HydrophobicContact CE1-CD2 3.62Å; V396-L404 HydrophobicContact CG1-CD1 4.14Å; V396-L404 HydrophobicContact CG1-CD2 4.42Å; V397-L404 VanDerWaalsContact CA-CD1 3.48Å; V397-L404 HydrophobicContact CB-CD1 4.18Å; V397-L404 HydrophobicContact CG2-CD1 3.82Å; P401-L404 PolarHBondContact O-N 2.89Å; H402-L404 VanDerWaalsContact C-N 3.26Å; H402-L404 PolarHBondContact O-N 3.14Å; L404-L406 PolarHBondContact O-N 3.4Å
405	T	90.4	Very high	92.7	Very high	110 Å²	110	65.5 Å²	65.5	68%	0.675	35%	0.35	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.4	-3.1	177.4	55.4	0	0	0	0	113.6	P401 H402 S407	P401-T405 WeakPolarHBondContact O-CB 3.41Å; P401-T405 VanDerWaalsContact O-CG2 3.24Å; P401-T405 WeakPolarHBondContact O-CG2 3.33Å; P401-T405 PolarHBondContact O-N 3.33Å; P401-T405 PolarHBondContact O-OG1 2.95Å; P401-T405 VanDerWaalsContact O-OG1 3.05Å; H402-T405 PolarHBondContact O-N 3.4Å; H402-T405 VanDerWaalsContact O-N 3.1Å; H402-T405 PolarHBondContact O-OG1 3.1Å; T405-S407 PolarHBondContact O-N 2.9Å
406	L	92.2	Very high	92.5	Very high	67 Å²	67	68.9 Å²	68.9	35%	0.351	36%	0.363	S	S	.	.	S	Bend	trans	-58.3	129.5	171.9	-66.9	174.6	0	0	0	109.7	Q234 H402 T403 L404 L408	Q234-L406 HydrophobicContact CG-CB 4.46Å; H402-L406 PolarHBondContact O-N 2.93Å; T403-L406 HydrophobicContact CG2-CD1 4.49Å; T403-L406 WeakPolarHBondContact O-CB 3.28Å; T403-L406 WeakPolarHBondContact O-CD1 3.4Å; T403-L406 WeakPolarHBondContact O-CG 3.43Å; T403-L406 PolarHBondContact O-N 3.31Å; L404-L406 PolarHBondContact O-N 3.4Å; L406-L408 PolarHBondContact O-N 3.43Å
407	S	89.9	Confident	92.4	Very high	105 Å²	105	72.6 Å²	72.6	73%	0.734	39%	0.385	S	S	*	.	P	Polyproline II helix	trans	-68.7	130.4	-179.6	56.3	0	0	0	0	110.3	T405	T405-S407 PolarHBondContact O-N 2.9Å
408	L	89.9	Confident	92.3	Very high	67 Å²	67	74.3 Å²	74.3	35%	0.351	39%	0.392	S	S	.	.	P	Polyproline II helix	trans	-54.9	136	170.6	-71.8	167.2	0	0	0	110.1	S230 L231 L406 F410 I412	S230-L408 WeakPolarHBondContact O-CD2 3.37Å; L231-L408 HydrophobicContact CD2-CD2 4.42Å; L406-L408 PolarHBondContact O-N 3.43Å; L408-F410 PolarHBondContact O-N 3.42Å; L408-I412 HydrophobicContact CD2-CG2 4.21Å
409	P	91.6	Very high	92.2	Very high	33 Å²	33	71.3 Å²	71.3	21%	0.214	39%	0.387	C	S	.	.	P	Polyproline II helix	trans	-51.9	141.1	170.5	-25.2	32.8	0	0	0	111.2	Y411 I412 S413	P409-Y411 VanDerWaalsContact C-N 3.3Å; P409-Y411 HydrophobicContact CB-CD1 3.91Å; P409-Y411 HydrophobicContact CB-CE1 3.41Å; P409-Y411 VanDerWaalsContact CB-CE1 3.41Å; P409-Y411 HydrophobicContact CG-CE1 4.4Å; P409-Y411 PolarHBondContact O-N 3.22Å; P409-I412 HydrophobicContact CB-CB 4.5Å; P409-I412 HydrophobicContact CB-CD1 4.09Å; P409-I412 HydrophobicContact CB-CG1 4.08Å; P409-I412 HydrophobicContact CG-CD1 3.82Å; P409-I412 HydrophobicContact CG-CG1 4.35Å; P409-I412 WeakPolarHBondContact O-CB 3.5Å; P409-I412 PolarHBondContact O-N 2.91Å; P409-S413 PolarHBondContact O-N 3.43Å
410	F	91.3	Very high	92.1	Very high	154 Å²	154	73.9 Å²	73.9	68%	0.675	41%	0.406	S	S	*	.	H	α-helix	trans	-55.8	-42.8	-169.7	-179.2	-106.8	0	0	0	113.2	L408 I412 S413 Q414	L408-F410 PolarHBondContact O-N 3.42Å; F410-I412 VanDerWaalsContact C-N 3.34Å; F410-I412 PolarHBondContact O-N 2.94Å; F410-S413 WeakPolarHBondContact O-CB 3.49Å; F410-S413 PolarHBondContact O-N 3.22Å; F410-Q414 HydrophobicContact CD1-CG 4.38Å; F410-Q414 HydrophobicContact CE1-CG 4.06Å; F410-Q414 HydrophobicContact CE2-CG 4.47Å; F410-Q414 HydrophobicContact CZ-CG 4.11Å; F410-Q414 WeakPolarHBondContact O-CG 3.45Å; F410-Q414 PolarHBondContact O-N 3.11Å
411	Y	90.7	Very high	92.3	Very high	133 Å²	133	76 Å²	76	52%	0.522	42%	0.421	S	S	.	.	H	α-helix	trans	-63.4	-38.5	178.8	63.2	-89.6	0	0	0	112.3	P409 Q414 C415	P409-Y411 VanDerWaalsContact C-N 3.3Å; P409-Y411 HydrophobicContact CB-CD1 3.91Å; P409-Y411 HydrophobicContact CB-CE1 3.41Å; P409-Y411 VanDerWaalsContact CB-CE1 3.41Å; P409-Y411 HydrophobicContact CG-CE1 4.4Å; P409-Y411 PolarHBondContact O-N 3.22Å; Y411-Q414 PolarHBondContact O-N 3.03Å; Y411-C415 PolarHBondContact O-N 2.99Å; Y411-C415 VanDerWaalsContact O-N 3.08Å; Y411-C415 PolarHBondContact O-SG 3.5Å; Y411-C415 VanDerWaalsContact O-SG 3.32Å
412	I	92	Very high	92.4	Very high	8 Å²	8	77.6 Å²	77.6	4%	0.041	42%	0.424	C	S	.	.	H	α-helix	trans	-66	-44.9	176.2	-57.7	-172.5	0	0	0	110.1	Y229 S230 L408 P409 F410 Q414 C415 W416	Y229-I412 WeakPolarHBondContact O-CD1 3.43Å; S230-I412 WeakPolarHBondContact OG-CG2 3.41Å; L408-I412 HydrophobicContact CD2-CG2 4.21Å; P409-I412 HydrophobicContact CB-CB 4.5Å; P409-I412 HydrophobicContact CB-CD1 4.09Å; P409-I412 HydrophobicContact CB-CG1 4.08Å; P409-I412 HydrophobicContact CG-CD1 3.82Å; P409-I412 HydrophobicContact CG-CG1 4.35Å; P409-I412 WeakPolarHBondContact O-CB 3.5Å; P409-I412 PolarHBondContact O-N 2.91Å; F410-I412 VanDerWaalsContact C-N 3.34Å; F410-I412 PolarHBondContact O-N 2.94Å; I412-Q414 VanDerWaalsContact C-N 3.3Å; I412-Q414 PolarHBondContact O-N 3.44Å; I412-C415 WeakPolarHBondContact O-CB 3.46Å; I412-C415 PolarHBondContact O-N 3.28Å; I412-C415 VanDerWaalsContact O-N 3.15Å; I412-W416 PolarHBondContact O-N 3.26Å
413	S	90.9	Very high	92.4	Very high	49 Å²	49	74.9 Å²	74.9	34%	0.343	42%	0.417	S	S	.	.	H	α-helix	trans	-59.4	-40.1	176.4	-176	0	0	0	0	112.1	P409 F410 W416 T417	P409-S413 PolarHBondContact O-N 3.43Å; F410-S413 WeakPolarHBondContact O-CB 3.49Å; F410-S413 PolarHBondContact O-N 3.22Å; S413-W416 PolarHBondContact O-N 3.47Å; S413-T417 WeakPolarHBondContact O-CB 3.45Å; S413-T417 PolarHBondContact O-N 2.65Å; S413-T417 PolarHBondContact O-OG1 2.96Å
414	Q	92.9	Very high	92.5	Very high	102 Å²	102	79.4 Å²	79.4	48%	0.477	44%	0.44	S	S	.	.	H	α-helix	trans	-62.9	-43.9	174.3	-71.1	179.1	-48.6	0	0	112	F410 Y411 I412 T417 L418	F410-Q414 HydrophobicContact CD1-CG 4.38Å; F410-Q414 HydrophobicContact CE1-CG 4.06Å; F410-Q414 HydrophobicContact CE2-CG 4.47Å; F410-Q414 HydrophobicContact CZ-CG 4.11Å; F410-Q414 WeakPolarHBondContact O-CG 3.45Å; F410-Q414 PolarHBondContact O-N 3.11Å; Y411-Q414 PolarHBondContact O-N 3.03Å; I412-Q414 VanDerWaalsContact C-N 3.3Å; I412-Q414 PolarHBondContact O-N 3.44Å; Q414-T417 PolarHBondContact O-N 3.3Å; Q414-L418 WeakPolarHBondContact O-CB 3.41Å; Q414-L418 PolarHBondContact O-N 3.45Å
415	C	92.7	Very high	92.8	Very high	65 Å²	65	81 Å²	81	44%	0.439	45%	0.452	S	S	.	.	H	α-helix	trans	-61	-46.5	177.2	-69.3	0	0	0	0	112.2	F226 Y411 I412 T417 L418 G419	F226-C415 HydrophobicContact CE2-CB 4.28Å; F226-C415 HydrophobicContact CZ-CB 3.66Å; Y411-C415 PolarHBondContact O-N 2.99Å; Y411-C415 VanDerWaalsContact O-N 3.08Å; Y411-C415 PolarHBondContact O-SG 3.5Å; Y411-C415 VanDerWaalsContact O-SG 3.32Å; I412-C415 WeakPolarHBondContact O-CB 3.46Å; I412-C415 PolarHBondContact O-N 3.28Å; I412-C415 VanDerWaalsContact O-N 3.15Å; C415-T417 PolarHBondContact O-N 3.37Å; C415-L418 PolarHBondContact O-N 2.65Å; C415-G419 PolarHBondContact O-N 2.61Å
416	W	94	Very high	93	Very high	72 Å²	72	80.2 Å²	80.2	27%	0.273	44%	0.437	S	S	.	.	H	α-helix	trans	-63.9	-39.4	175.5	-81.2	105.3	0	0	0	112.8	F226 L227 S230 I412 S413 G419 S420	F226-W416 HydrophobicContact CD1-CD2 4.41Å; F226-W416 AromaticContact CD1-CE2 3.68Å; F226-W416 AromaticContact CD1-CH2 3.88Å; F226-W416 HydrophobicContact CD1-CH2 3.88Å; F226-W416 AromaticContact CD1-CZ2 3.37Å; F226-W416 HydrophobicContact CD1-CZ2 3.37Å; F226-W416 AromaticContact CE1-CD1 3.85Å; F226-W416 AromaticContact CE1-CD2 3.73Å; F226-W416 HydrophobicContact CE1-CD2 3.73Å; F226-W416 AromaticContact CE1-CE2 3.26Å; F226-W416 HydrophobicContact CE1-CE3 4.34Å; F226-W416 HydrophobicContact CE1-CG 4.09Å; F226-W416 HydrophobicContact CE1-CH2 4.17Å; F226-W416 AromaticContact CE1-CZ2 3.52Å; F226-W416 HydrophobicContact CE1-CZ2 3.52Å; F226-W416 AromaticContact CE1-NE1 3.34Å; F226-W416 VanDerWaalsContact CE1-NE1 3.34Å; L227-W416 HydrophobicContact CD2-CH2 3.92Å; L227-W416 HydrophobicContact CD2-CZ2 3.61Å; L227-W416 HydrophobicContact CG-CH2 4.3Å; L227-W416 HydrophobicContact CG-CZ2 4.15Å; S230-W416 PolarHBondContact OG-NE1 2.74Å; I412-W416 PolarHBondContact O-N 3.26Å; S413-W416 PolarHBondContact O-N 3.47Å; W416-G419 PolarHBondContact O-N 3.32Å; W416-S420 VanDerWaalsContact O-CB 3.27Å; W416-S420 WeakPolarHBondContact O-CB 3.27Å; W416-S420 PolarHBondContact O-N 3.29Å; W416-S420 PolarHBondContact O-OG 3.45Å
417	T	94.1	Very high	93	Very high	81 Å²	81	77.9 Å²	77.9	50%	0.497	43%	0.425	S	S	.	.	H	α-helix	trans	-62.8	-48.3	176.9	-59.4	0	0	0	0	110.4	S413 Q414 C415 S420 V421	S413-T417 WeakPolarHBondContact O-CB 3.45Å; S413-T417 PolarHBondContact O-N 2.65Å; S413-T417 PolarHBondContact O-OG1 2.96Å; Q414-T417 PolarHBondContact O-N 3.3Å; C415-T417 PolarHBondContact O-N 3.37Å; T417-S420 PolarHBondContact O-N 3.38Å; T417-V421 WeakPolarHBondContact O-CB 3.46Å; T417-V421 VanDerWaalsContact O-CG2 3.28Å; T417-V421 WeakPolarHBondContact O-CG2 3.42Å; T417-V421 PolarHBondContact O-N 3.2Å
418	L	94.9	Very high	93.2	Very high	108 Å²	108	76.3 Å²	76.3	57%	0.565	41%	0.411	S	S	*	.	H	α-helix	trans	-60.3	-49.1	176.9	177.9	62.7	0	0	0	111.4	Q414 C415 S420 V421 L422	Q414-L418 WeakPolarHBondContact O-CB 3.41Å; Q414-L418 PolarHBondContact O-N 3.45Å; C415-L418 PolarHBondContact O-N 2.65Å; L418-S420 VanDerWaalsContact C-N 3.34Å; L418-S420 PolarHBondContact O-N 3.31Å; L418-V421 PolarHBondContact O-N 3.41Å; L418-L422 HydrophobicContact CD1-CD1 4.23Å; L418-L422 HydrophobicContact CD1-CG 4.25Å; L418-L422 HydrophobicContact CG-CD1 4.05Å; L418-L422 HydrophobicContact CG-CG 4.48Å; L418-L422 VanDerWaalsContact O-CG 3.28Å; L418-L422 WeakPolarHBondContact O-CG 3.21Å; L418-L422 PolarHBondContact O-N 2.94Å
419	G	93	Very high	93.3	Very high	31 Å²	31	79.1 Å²	79.1	32%	0.32	42%	0.417	S	S	.	.	H	α-helix	trans	-58.3	-44.9	178	0	0	0	0	0	112.4	C415 W416 L422 V423	C415-G419 PolarHBondContact O-N 2.61Å; W416-G419 PolarHBondContact O-N 3.32Å; G419-L422 PolarHBondContact O-N 3.48Å; G419-V423 WeakPolarHBondContact O-CG2 3.35Å; G419-V423 PolarHBondContact O-N 2.97Å
420	S	93.9	Very high	93.3	Very high	62 Å²	62	79 Å²	79	43%	0.434	41%	0.412	S	S	.	.	H	α-helix	trans	-62.5	-45.1	177.2	-59.7	0	0	0	0	111.7	W416 T417 L418 L422 V423 L424	W416-S420 VanDerWaalsContact O-CB 3.27Å; W416-S420 WeakPolarHBondContact O-CB 3.27Å; W416-S420 PolarHBondContact O-N 3.29Å; W416-S420 PolarHBondContact O-OG 3.45Å; T417-S420 PolarHBondContact O-N 3.38Å; L418-S420 VanDerWaalsContact C-N 3.34Å; L418-S420 PolarHBondContact O-N 3.31Å; S420-L422 PolarHBondContact O-N 2.99Å; S420-V423 PolarHBondContact O-N 3.5Å; S420-L424 WeakPolarHBondContact O-CB 3.34Å; S420-L424 WeakPolarHBondContact O-CG 3.49Å; S420-L424 PolarHBondContact O-N 3.5Å
421	V	96.3	Very high	93.3	Very high	76 Å²	76	72.9 Å²	72.9	46%	0.461	39%	0.385	S	S	.	.	H	α-helix	trans	-60.4	-45.9	175.6	169.7	0	0	0	0	110.6	T417 L418 V423 L424 T425	T417-V421 WeakPolarHBondContact O-CB 3.46Å; T417-V421 VanDerWaalsContact O-CG2 3.28Å; T417-V421 WeakPolarHBondContact O-CG2 3.42Å; T417-V421 PolarHBondContact O-N 3.2Å; L418-V421 PolarHBondContact O-N 3.41Å; V421-V423 PolarHBondContact O-N 3.01Å; V421-L424 PolarHBondContact O-N 3.2Å; V421-T425 WeakPolarHBondContact O-CB 3.39Å; V421-T425 PolarHBondContact O-N 3.44Å; V421-T425 PolarHBondContact O-OG1 3.38Å
422	L	95.1	Very high	93.2	Very high	106 Å²	106	71.7 Å²	71.7	56%	0.555	38%	0.383	S	S	*	.	H	α-helix	trans	-60.7	-45.9	178.9	-71.5	171.8	0	0	0	112.3	L418 G419 S420 T425 W426	L418-L422 HydrophobicContact CD1-CD1 4.23Å; L418-L422 HydrophobicContact CD1-CG 4.25Å; L418-L422 HydrophobicContact CG-CD1 4.05Å; L418-L422 HydrophobicContact CG-CG 4.48Å; L418-L422 VanDerWaalsContact O-CG 3.28Å; L418-L422 WeakPolarHBondContact O-CG 3.21Å; L418-L422 PolarHBondContact O-N 2.94Å; G419-L422 PolarHBondContact O-N 3.48Å; S420-L422 PolarHBondContact O-N 2.99Å; L422-T425 PolarHBondContact O-N 3.08Å; L422-W426 WeakPolarHBondContact O-CB 3.42Å; L422-W426 PolarHBondContact O-N 2.98Å
423	V	93.5	Very high	92.9	Very high	74 Å²	74	75.8 Å²	75.8	45%	0.448	40%	0.404	S	S	.	.	H	α-helix	trans	-62.4	-43.4	177.2	170.9	0	0	0	0	110.9	W314 G419 S420 V421 T427	W314-V423 HydrophobicContact CZ2-CG1 4.14Å; G419-V423 WeakPolarHBondContact O-CG2 3.35Å; G419-V423 PolarHBondContact O-N 2.97Å; S420-V423 PolarHBondContact O-N 3.5Å; V421-V423 PolarHBondContact O-N 3.01Å; V423-T427 WeakPolarHBondContact O-CB 3.35Å; V423-T427 PolarHBondContact O-N 3.15Å; V423-T427 PolarHBondContact O-OG1 3.48Å
424	L	94.6	Very high	92.4	Very high	112 Å²	112	77.9 Å²	77.9	59%	0.586	41%	0.405	S	S	*	.	H	α-helix	trans	-65.1	-48.2	177.3	-72.3	172.2	0	0	0	111.7	S420 V421 W426 T427 V428	S420-L424 WeakPolarHBondContact O-CB 3.34Å; S420-L424 WeakPolarHBondContact O-CG 3.49Å; S420-L424 PolarHBondContact O-N 3.5Å; V421-L424 PolarHBondContact O-N 3.2Å; L424-W426 VanDerWaalsContact C-N 3.33Å; L424-W426 PolarHBondContact O-N 3.28Å; L424-T427 WeakPolarHBondContact O-CB 3.48Å; L424-T427 PolarHBondContact O-N 3.49Å; L424-T427 VanDerWaalsContact O-N 3.16Å; L424-V428 WeakPolarHBondContact O-CG2 3.3Å; L424-V428 PolarHBondContact O-N 3Å
425	T	94.8	Very high	91.6	Very high	86 Å²	86	75.6 Å²	75.6	53%	0.528	40%	0.396	S	S	.	.	H	α-helix	trans	-59.5	-44.8	177.6	-60.4	0	0	0	0	110.9	V421 L422 T427 V428 W429	V421-T425 WeakPolarHBondContact O-CB 3.39Å; V421-T425 PolarHBondContact O-N 3.44Å; V421-T425 PolarHBondContact O-OG1 3.38Å; L422-T425 PolarHBondContact O-N 3.08Å; T425-T427 VanDerWaalsContact C-N 3.34Å; T425-T427 PolarHBondContact O-N 3.31Å; T425-V428 PolarHBondContact O-N 3.32Å; T425-W429 VanDerWaalsContact O-CB 3.24Å; T425-W429 WeakPolarHBondContact O-CB 3.35Å; T425-W429 PolarHBondContact O-N 3.36Å
426	W	93.8	Very high	90.8	Very high	94 Å²	94	77.7 Å²	77.7	36%	0.356	40%	0.402	S	S	.	.	H	α-helix	trans	-61.8	-42.8	175.7	-176.5	92	0	0	0	111.8	A308 W314 L422 L424 W429 R430 F431	A308-W426 HydrophobicContact CB-CH2 4.17Å; W314-W426 HydrophobicContact CD2-CH2 4.47Å; W314-W426 AromaticContact CD2-CZ3 3.66Å; W314-W426 HydrophobicContact CD2-CZ3 3.66Å; W314-W426 AromaticContact CE2-CE3 3.98Å; W314-W426 AromaticContact CE2-CZ3 3.57Å; W314-W426 HydrophobicContact CE3-CH2 4.07Å; W314-W426 AromaticContact CE3-CZ3 3.64Å; W314-W426 HydrophobicContact CE3-CZ3 3.64Å; W314-W426 HydrophobicContact CG-CZ3 4.46Å; W314-W426 AromaticContact CH2-CE3 3.85Å; W314-W426 HydrophobicContact CH2-CE3 3.85Å; W314-W426 HydrophobicContact CH2-CH2 4.21Å; W314-W426 AromaticContact CH2-CZ3 3.5Å; W314-W426 HydrophobicContact CH2-CZ3 3.5Å; W314-W426 VanDerWaalsContact CH2-CZ3 3.5Å; W314-W426 AromaticContact CZ2-CE3 3.62Å; W314-W426 HydrophobicContact CZ2-CE3 3.62Å; W314-W426 AromaticContact CZ2-CZ3 3.49Å; W314-W426 HydrophobicContact CZ2-CZ3 3.49Å; W314-W426 VanDerWaalsContact CZ2-CZ3 3.49Å; W314-W426 HydrophobicContact CZ3-CE3 4.38Å; W314-W426 AromaticContact CZ3-CH2 3.94Å; W314-W426 HydrophobicContact CZ3-CH2 3.94Å; W314-W426 AromaticContact CZ3-CZ3 3.57Å; W314-W426 HydrophobicContact CZ3-CZ3 3.57Å; L422-W426 WeakPolarHBondContact O-CB 3.42Å; L422-W426 PolarHBondContact O-N 2.98Å; L424-W426 VanDerWaalsContact C-N 3.33Å; L424-W426 PolarHBondContact O-N 3.28Å; W426-W429 PolarHBondContact O-N 3Å; W426-R430 HydrophobicContact CD2-CB 4.42Å; W426-R430 HydrophobicContact CE3-CB 4.44Å; W426-R430 HydrophobicContact CH2-CB 4.46Å; W426-R430 HydrophobicContact CH2-CG 4.11Å; W426-R430 HydrophobicContact CZ2-CB 4.43Å; W426-R430 HydrophobicContact CZ2-CG 4.24Å; W426-R430 HydrophobicContact CZ3-CB 4.45Å; W426-R430 HydrophobicContact CZ3-CG 4.42Å; W426-R430 WeakPolarHBondContact O-CB 3.27Å; W426-R430 PolarHBondContact O-N 2.87Å; W426-F431 HydrophobicContact CZ3-CE2 4.09Å
427	T	93.8	Very high	89.8	Confident	17 Å²	17	77.6 Å²	77.6	10%	0.104	41%	0.409	C	S	.	.	H	α-helix	trans	-60.6	-49.5	177.8	-57.6	0	0	0	0	111.1	L311 W314 V423 L424 T425 R430 F431	L311-T427 HydrophobicContact CD1-CG2 3.9Å; W314-T427 PolarHBondContact NE1-OG1 2.93Å; V423-T427 WeakPolarHBondContact O-CB 3.35Å; V423-T427 PolarHBondContact O-N 3.15Å; V423-T427 PolarHBondContact O-OG1 3.48Å; L424-T427 WeakPolarHBondContact O-CB 3.48Å; L424-T427 PolarHBondContact O-N 3.49Å; L424-T427 VanDerWaalsContact O-N 3.16Å; T425-T427 VanDerWaalsContact C-N 3.34Å; T425-T427 PolarHBondContact O-N 3.31Å; T427-R430 PolarHBondContact O-N 2.76Å; T427-F431 HydrophobicContact CG2-CD2 4.1Å; T427-F431 WeakPolarHBondContact O-CD2 3.28Å; T427-F431 PolarHBondContact O-N 2.75Å; T427-F431 VanDerWaalsContact O-N 3.1Å
428	V	93.3	Very high	88.9	Confident	73 Å²	73	78 Å²	78	44%	0.442	41%	0.408	S	S	.	.	H	α-helix	trans	-61.5	-47.6	178.2	172.8	0	0	0	0	110.6	L424 T425 F432 L433	L424-V428 WeakPolarHBondContact O-CG2 3.3Å; L424-V428 PolarHBondContact O-N 3Å; T425-V428 PolarHBondContact O-N 3.32Å; V428-F432 WeakPolarHBondContact O-CB 3.38Å; V428-F432 PolarHBondContact O-N 2.9Å; V428-L433 HydrophobicContact CG1-CG 4.46Å; V428-L433 PolarHBondContact O-N 3.4Å
429	W	93.1	Very high	88	Confident	126 Å²	126	80.7 Å²	80.7	48%	0.477	41%	0.41	S	S	.	.	I	π-helix	trans	-61.6	-47.5	179.8	176.5	79.4	0	0	0	112.3	T425 W426 L433 R434	T425-W429 VanDerWaalsContact O-CB 3.24Å; T425-W429 WeakPolarHBondContact O-CB 3.35Å; T425-W429 PolarHBondContact O-N 3.36Å; W426-W429 PolarHBondContact O-N 3Å; W429-L433 PolarHBondContact O-N 3.48Å; W429-R434 WeakPolarHBondContact O-CB 3.22Å; W429-R434 PolarHBondContact O-N 3.27Å
430	R	90.6	Very high	87.1	Confident	30 Å²	30	87 Å²	87	11%	0.113	43%	0.425	C	S	.	.	I	π-helix	trans	-68.2	-43.8	-174.8	171.8	59.8	-166.8	100.7	-1.5	113	A308 W426 T427 R434	A308-R430 VanDerWaalsContact O-CZ 3.28Å; A308-R430 PolarHBondContact O-NE 3.4Å; A308-R430 PolarHBondContact O-NH2 3.27Å; W426-R430 HydrophobicContact CD2-CB 4.42Å; W426-R430 HydrophobicContact CE3-CB 4.44Å; W426-R430 HydrophobicContact CH2-CB 4.46Å; W426-R430 HydrophobicContact CH2-CG 4.11Å; W426-R430 HydrophobicContact CZ2-CB 4.43Å; W426-R430 HydrophobicContact CZ2-CG 4.24Å; W426-R430 HydrophobicContact CZ3-CB 4.45Å; W426-R430 HydrophobicContact CZ3-CG 4.42Å; W426-R430 WeakPolarHBondContact O-CB 3.27Å; W426-R430 PolarHBondContact O-N 2.87Å; T427-R430 PolarHBondContact O-N 2.76Å; R430-R434 VanDerWaalsContact CD-NH1 3.32Å; R430-R434 VanDerWaalsContact NE-CZ 3.27Å; R430-R434 VanDerWaalsContact NE-NH2 3.13Å
431	F	90.7	Very high	86.4	Confident	26 Å²	26	90.1 Å²	90.1	11%	0.114	43%	0.431	C	S	.	.	I	π-helix	trans	-101.6	-21.6	-168.9	-66.7	-69.8	0	0	0	114.4	L311 W314 W426 T427	L311-F431 HydrophobicContact CB-CD1 4.27Å; L311-F431 HydrophobicContact CB-CG 4.24Å; L311-F431 HydrophobicContact CD1-CB 4.41Å; L311-F431 HydrophobicContact CD1-CD2 3.93Å; L311-F431 HydrophobicContact CD1-CE2 4.47Å; L311-F431 HydrophobicContact CD1-CG 4.19Å; W314-F431 HydrophobicContact CB-CE2 3.61Å; W314-F431 HydrophobicContact CB-CZ 3.61Å; W314-F431 AromaticContact CD1-CE2 3.81Å; W314-F431 HydrophobicContact CD2-CE2 4.28Å; W314-F431 AromaticContact CG-CE2 3.61Å; W314-F431 HydrophobicContact CG-CE2 3.61Å; W314-F431 HydrophobicContact CG-CZ 4.1Å; W426-F431 HydrophobicContact CZ3-CE2 4.09Å; T427-F431 HydrophobicContact CG2-CD2 4.1Å; T427-F431 WeakPolarHBondContact O-CD2 3.28Å; T427-F431 PolarHBondContact O-N 2.75Å; T427-F431 VanDerWaalsContact O-N 3.1Å
432	F	88.9	Confident	85.6	Confident	108 Å²	108	92.4 Å²	92.4	47%	0.474	44%	0.437	S	S	.	.	I	π-helix	trans	-109.3	-59.1	178.4	-59.3	-94.3	0	0	0	110.6	L311 V428 I436	L311-F432 HydrophobicContact CD2-CE2 4.27Å; L311-F432 HydrophobicContact CD2-CZ 3.98Å; V428-F432 WeakPolarHBondContact O-CB 3.38Å; V428-F432 PolarHBondContact O-N 2.9Å; F432-I436 WeakPolarHBondContact O-CB 3.28Å; F432-I436 VanDerWaalsContact O-CD1 3.29Å; F432-I436 WeakPolarHBondContact O-CD1 3.38Å; F432-I436 WeakPolarHBondContact O-CG1 3.48Å; F432-I436 PolarHBondContact O-N 2.88Å
433	L	85.8	Confident	84.9	Confident	93 Å²	93	90.7 Å²	90.7	49%	0.487	43%	0.431	S	S	.	.	I	π-helix	trans	-70.7	-46.6	-172.1	-59	179.4	0	0	0	113.3	V428 W429 D435 T437	V428-L433 HydrophobicContact CG1-CG 4.46Å; V428-L433 PolarHBondContact O-N 3.4Å; W429-L433 PolarHBondContact O-N 3.48Å; L433-D435 VanDerWaalsContact C-N 3.33Å; L433-D435 PolarHBondContact O-N 2.89Å; L433-T437 WeakPolarHBondContact O-CB 3.24Å; L433-T437 PolarHBondContact O-N 3.41Å; L433-T437 PolarHBondContact O-OG1 3.29Å
434	R	81	Confident	84.4	Confident	93 Å²	93	94.9 Å²	94.9	35%	0.351	44%	0.439	S	S	.	.	H	α-helix	trans	-65.5	-38.8	179.9	-167.9	175	91.7	171.6	20.1	111.8	W429 R430 T437 L438	W429-R434 WeakPolarHBondContact O-CB 3.22Å; W429-R434 PolarHBondContact O-N 3.27Å; R430-R434 VanDerWaalsContact CD-NH1 3.32Å; R430-R434 VanDerWaalsContact NE-CZ 3.27Å; R430-R434 VanDerWaalsContact NE-NH2 3.13Å; R434-T437 PolarHBondContact O-N 3.42Å; R434-L438 HydrophobicContact CG-CD1 4.19Å; R434-L438 WeakPolarHBondContact O-CB 3.37Å; R434-L438 VanDerWaalsContact O-CG 3.28Å; R434-L438 WeakPolarHBondContact O-CG 3.29Å; R434-L438 PolarHBondContact O-N 2.97Å
435	D	75.2	Confident	83.6	Confident	54 Å²	54	98.7 Å²	98.7	29%	0.289	45%	0.446	S	S	.	.	H	α-helix	trans	-69.2	-42.6	-178.8	-138.6	55.6	0	0	0	111.2	L433 T437 L438 R439	L433-D435 VanDerWaalsContact C-N 3.33Å; L433-D435 PolarHBondContact O-N 2.89Å; D435-T437 VanDerWaalsContact C-N 3.35Å; D435-L438 PolarHBondContact O-N 2.89Å; D435-R439 WeakPolarHBondContact O-CG 3.43Å; D435-R439 PolarHBondContact O-N 2.93Å; D435-R439 IonicContact OD2-CZ 3.53Å; D435-R439 IonicContact OD2-NE 3.56Å; D435-R439 IonicContact OD2-NH2 2.73Å; D435-R439 PolarHBondContact OD2-NH2 3.38Å
436	I	75.9	Confident	82.9	Confident	110 Å²	110	100.5 Å²	100.5	56%	0.564	45%	0.448	S	S	*	.	H	α-helix	trans	-60.3	-45.1	170.7	-68.3	165.3	0	0	0	110.7	F432 L438 R439 Y440	F432-I436 WeakPolarHBondContact O-CB 3.28Å; F432-I436 VanDerWaalsContact O-CD1 3.29Å; F432-I436 WeakPolarHBondContact O-CD1 3.38Å; F432-I436 WeakPolarHBondContact O-CG1 3.48Å; F432-I436 PolarHBondContact O-N 2.88Å; I436-L438 PolarHBondContact O-N 3.43Å; I436-R439 PolarHBondContact O-N 2.94Å; I436-Y440 WeakPolarHBondContact O-CB 3.39Å; I436-Y440 PolarHBondContact O-N 3.49Å
437	T	74.1	Confident	82.1	Confident	70 Å²	70	103 Å²	103	43%	0.429	46%	0.462	S	S	.	.	H	α-helix	trans	-64.5	-39.7	-178.9	-56.1	0	0	0	0	112.1	L433 R434 D435 K441	L433-T437 WeakPolarHBondContact O-CB 3.24Å; L433-T437 PolarHBondContact O-N 3.41Å; L433-T437 PolarHBondContact O-OG1 3.29Å; R434-T437 PolarHBondContact O-N 3.42Å; D435-T437 VanDerWaalsContact C-N 3.35Å; T437-K441 WeakPolarHBondContact O-CB 3.13Å; T437-K441 WeakPolarHBondContact O-CG 3.41Å; T437-K441 PolarHBondContact O-N 3.42Å
438	L	75.2	Confident	81.3	Confident	88 Å²	88	107.5 Å²	107.5	46%	0.461	48%	0.481	S	S	.	.	H	α-helix	trans	-67.6	-47	176.6	-73.9	171.7	0	0	0	111.2	R434 D435 I436 Y440 K441 E442	R434-L438 HydrophobicContact CG-CD1 4.19Å; R434-L438 WeakPolarHBondContact O-CB 3.37Å; R434-L438 VanDerWaalsContact O-CG 3.28Å; R434-L438 WeakPolarHBondContact O-CG 3.29Å; R434-L438 PolarHBondContact O-N 2.97Å; D435-L438 PolarHBondContact O-N 2.89Å; I436-L438 PolarHBondContact O-N 3.43Å; L438-Y440 VanDerWaalsContact C-N 3.32Å; L438-Y440 PolarHBondContact O-N 2.96Å; L438-K441 PolarHBondContact O-N 3.45Å; L438-E442 WeakPolarHBondContact O-CB 3.34Å; L438-E442 PolarHBondContact O-N 2.79Å
439	R	75.1	Confident	80.4	Confident	166 Å²	166	110 Å²	110	63%	0.626	49%	0.488	S	S	*	.	H	α-helix	trans	-57.7	-45.4	174.2	-71.2	-176.4	-139.6	-132.6	5.1	111.6	D435 I436 K441 E442 T443	D435-R439 WeakPolarHBondContact O-CG 3.43Å; D435-R439 PolarHBondContact O-N 2.93Å; D435-R439 IonicContact OD2-CZ 3.53Å; D435-R439 IonicContact OD2-NE 3.56Å; D435-R439 IonicContact OD2-NH2 2.73Å; D435-R439 PolarHBondContact OD2-NH2 3.38Å; I436-R439 PolarHBondContact O-N 2.94Å; R439-K441 PolarHBondContact O-N 3.18Å; R439-E442 PolarHBondContact O-N 3.28Å; R439-T443 PolarHBondContact O-N 2.88Å; R439-T443 PolarHBondContact O-OG1 2.87Å
440	Y	73.8	Confident	79.3	Confident	162 Å²	162	107 Å²	107	64%	0.635	49%	0.486	S	S	*	.	H	α-helix	trans	-60.4	-42.8	177.1	-178.3	-96.1	0	0	0	112.6	I436 L438 E442 R444	I436-Y440 WeakPolarHBondContact O-CB 3.39Å; I436-Y440 PolarHBondContact O-N 3.49Å; L438-Y440 VanDerWaalsContact C-N 3.32Å; L438-Y440 PolarHBondContact O-N 2.96Å; Y440-E442 VanDerWaalsContact C-N 3.34Å; Y440-R444 WeakPolarHBondContact O-CB 3.45Å; Y440-R444 PolarHBondContact O-N 3.47Å
441	K	79	Confident	78.4	Confident	128 Å²	128	112.9 Å²	112.9	56%	0.557	51%	0.513	S	S	*	.	H	α-helix	trans	-64.1	-37.9	175.4	-79.7	-178.1	178.6	-177.3	0	112.3	T437 L438 R439 R444 R445	T437-K441 WeakPolarHBondContact O-CB 3.13Å; T437-K441 WeakPolarHBondContact O-CG 3.41Å; T437-K441 PolarHBondContact O-N 3.42Å; L438-K441 PolarHBondContact O-N 3.45Å; R439-K441 PolarHBondContact O-N 3.18Å; K441-R444 PolarHBondContact O-N 3.01Å; K441-R445 WeakPolarHBondContact O-CG 3.5Å; K441-R445 PolarHBondContact O-N 2.84Å
442	E	81.1	Confident	77.4	Confident	124 Å²	124	116.7 Å²	116.7	58%	0.579	53%	0.534	S	S	*	.	H	α-helix	trans	-70.1	-44.4	178.5	-166.3	145	-153.5	0	0	111.8	L438 R439 Y440 R444 R445 Q446	L438-E442 WeakPolarHBondContact O-CB 3.34Å; L438-E442 PolarHBondContact O-N 2.79Å; R439-E442 PolarHBondContact O-N 3.28Å; Y440-E442 VanDerWaalsContact C-N 3.34Å; E442-R444 VanDerWaalsContact C-N 3.25Å; E442-R444 PolarHBondContact O-N 3.43Å; E442-R445 PolarHBondContact O-N 3.07Å; E442-R445 VanDerWaalsContact O-N 3.14Å; E442-Q446 WeakPolarHBondContact O-CG 3.37Å; E442-Q446 PolarHBondContact O-N 2.71Å
443	T	79.9	Confident	76.2	Confident	71 Å²	71	116.7 Å²	116.7	44%	0.436	54%	0.539	S	S	.	.	H	α-helix	trans	-58.2	-38.8	171.4	-48.1	0	0	0	0	111.6	R439 K447	R439-T443 PolarHBondContact O-N 2.88Å; R439-T443 PolarHBondContact O-OG1 2.87Å; T443-K447 WeakPolarHBondContact O-CB 3.32Å; T443-K447 WeakPolarHBondContact O-CG 3.36Å; T443-K447 PolarHBondContact O-N 2.94Å
444	R	81.9	Confident	74.8	Confident	162 Å²	162	119 Å²	119	61%	0.611	55%	0.547	S	S	*	.	H	α-helix	trans	-67.9	-41.2	176.6	-168.8	-178.8	178.8	-172.9	1.2	112	Y440 K441 E442 K447 Q448	Y440-R444 WeakPolarHBondContact O-CB 3.45Å; Y440-R444 PolarHBondContact O-N 3.47Å; K441-R444 PolarHBondContact O-N 3.01Å; E442-R444 VanDerWaalsContact C-N 3.25Å; E442-R444 PolarHBondContact O-N 3.43Å; R444-K447 PolarHBondContact O-N 2.95Å; R444-Q448 PolarHBondContact O-N 3.06Å
445	R	79.1	Confident	73.6	Confident	192 Å²	192	117 Å²	117	73%	0.725	56%	0.556	S	S	*	*	H	α-helix	trans	-63.8	-44.6	175.5	-79	179.3	173.9	-179.3	-3.7	112	K441 E442 K447 Q448 Q449	K441-R445 WeakPolarHBondContact O-CG 3.5Å; K441-R445 PolarHBondContact O-N 2.84Å; E442-R445 PolarHBondContact O-N 3.07Å; E442-R445 VanDerWaalsContact O-N 3.14Å; R445-K447 VanDerWaalsContact C-N 3.33Å; R445-K447 PolarHBondContact O-N 2.87Å; R445-Q448 WeakPolarHBondContact O-CB 3.34Å; R445-Q448 PolarHBondContact O-N 3.4Å; R445-Q448 VanDerWaalsContact O-N 3.1Å; R445-Q449 WeakPolarHBondContact O-CB 3.42Å; R445-Q449 PolarHBondContact O-N 3Å
446	Q	79.2	Confident	72.7	Confident	124 Å²	124	118.8 Å²	118.8	58%	0.579	57%	0.572	S	S	*	*	H	α-helix	trans	-59.9	-42.4	175.1	-72.7	178	-7.9	0	0	111.8	E442 Q448 Q449 S450	E442-Q446 WeakPolarHBondContact O-CG 3.37Å; E442-Q446 PolarHBondContact O-N 2.71Å; Q446-Q448 VanDerWaalsContact C-N 3.3Å; Q446-Q448 PolarHBondContact O-N 3Å; Q446-Q449 PolarHBondContact O-N 3.43Å; Q446-S450 WeakPolarHBondContact O-CB 3.45Å; Q446-S450 PolarHBondContact O-N 2.89Å; Q446-S450 PolarHBondContact O-OG 3.19Å
447	K	78.2	Confident	71.5	Confident	147 Å²	147	117.5 Å²	117.5	64%	0.639	58%	0.579	S	S	*	*	H	α-helix	trans	-64.9	-30.9	174.3	-78.7	-175.5	178.4	-174.1	0	113.8	T443 R444 R445 S450 K451	T443-K447 WeakPolarHBondContact O-CB 3.32Å; T443-K447 WeakPolarHBondContact O-CG 3.36Å; T443-K447 PolarHBondContact O-N 2.94Å; R444-K447 PolarHBondContact O-N 2.95Å; R445-K447 VanDerWaalsContact C-N 3.33Å; R445-K447 PolarHBondContact O-N 2.87Å; K447-S450 WeakPolarHBondContact CA-OG 3.49Å; K447-S450 PolarHBondContact O-OG 3.01Å; K447-K451 PolarHBondContact O-N 3.05Å
448	Q	76.5	Confident	70.6	Confident	110 Å²	110	120.3 Å²	120.3	51%	0.514	60%	0.595	S	S	.	*	H	α-helix	trans	-73.3	-47.1	176.8	-159.3	96.6	12.8	0	0	110	R444 R445 Q446 S450 K451 D452	R444-Q448 PolarHBondContact O-N 3.06Å; R445-Q448 WeakPolarHBondContact O-CB 3.34Å; R445-Q448 PolarHBondContact O-N 3.4Å; R445-Q448 VanDerWaalsContact O-N 3.1Å; Q446-Q448 VanDerWaalsContact C-N 3.3Å; Q446-Q448 PolarHBondContact O-N 3Å; Q448-S450 PolarHBondContact O-N 3.01Å; Q448-K451 WeakPolarHBondContact O-CA 3.24Å; Q448-K451 VanDerWaalsContact O-CB 3.27Å; Q448-K451 WeakPolarHBondContact O-CB 3.48Å; Q448-K451 PolarHBondContact O-N 3.39Å; Q448-D452 PolarHBondContact O-N 3.44Å
449	Q	75.1	Confident	69.2	Low	126 Å²	126	119.1 Å²	119.1	59%	0.589	61%	0.605	S	S	*	*	H	α-helix	trans	-66.3	-39.1	-179.5	-159.8	162.4	-0.5	0	0	112.2	R445 Q446 K451 D452 D453	R445-Q449 WeakPolarHBondContact O-CB 3.42Å; R445-Q449 PolarHBondContact O-N 3Å; Q446-Q449 PolarHBondContact O-N 3.43Å; Q449-K451 PolarHBondContact O-N 3.03Å; Q449-D452 PolarHBondContact O-N 3.24Å; Q449-D453 PolarHBondContact O-N 2.99Å
450	S	69.9	Low	67.7	Low	63 Å²	63	118.9 Å²	118.9	44%	0.441	62%	0.616	S	S	.	*	H	α-helix	trans	-62.8	-28.6	171.6	66.6	0	0	0	0	113.1	Q446 K447 Q448 Q454	Q446-S450 WeakPolarHBondContact O-CB 3.45Å; Q446-S450 PolarHBondContact O-N 2.89Å; Q446-S450 PolarHBondContact O-OG 3.19Å; K447-S450 WeakPolarHBondContact CA-OG 3.49Å; K447-S450 PolarHBondContact O-OG 3.01Å; Q448-S450 PolarHBondContact O-N 3.01Å; S450-Q454 WeakPolarHBondContact O-CB 3.38Å; S450-Q454 PolarHBondContact O-N 2.81Å
451	K	71.4	Confident	66.1	Low	154 Å²	154	114.2 Å²	114.2	67%	0.67	62%	0.616	S	S	*	*	H	α-helix	trans	-77.2	-38.4	177.6	-127.1	180	179.2	-174.3	0	111.5	K447 Q448 Q449 G455	K447-K451 PolarHBondContact O-N 3.05Å; Q448-K451 WeakPolarHBondContact O-CA 3.24Å; Q448-K451 VanDerWaalsContact O-CB 3.27Å; Q448-K451 WeakPolarHBondContact O-CB 3.48Å; Q448-K451 PolarHBondContact O-N 3.39Å; Q449-K451 PolarHBondContact O-N 3.03Å; K451-G455 PolarHBondContact O-N 3.44Å
452	D	68.8	Low	64.4	Low	105 Å²	105	115.8 Å²	115.8	56%	0.561	63%	0.631	S	S	*	*	H	α-helix	trans	-70.4	-39.1	177.3	-65	-23.2	0	0	0	111.2	Q448 Q449 G455 S456	Q448-D452 PolarHBondContact O-N 3.44Å; Q449-D452 PolarHBondContact O-N 3.24Å; D452-G455 PolarHBondContact O-N 3.37Å; D452-S456 PolarHBondContact O-N 3.1Å
453	D	63.2	Low	62.2	Low	108 Å²	108	119.4 Å²	119.4	58%	0.578	65%	0.648	S	S	*	*	H	α-helix	trans	-65.7	-38.7	173.9	-72.9	-22	0	0	0	112.1	Q449 S456 A457	Q449-D453 PolarHBondContact O-N 2.99Å; D453-S456 PolarHBondContact O-N 2.97Å; D453-A457 PolarHBondContact O-N 3.32Å; D453-A457 VanDerWaalsContact O-N 3.11Å
454	Q	57.9	Low	59.9	Low	142 Å²	142	123.5 Å²	123.5	66%	0.664	66%	0.662	S	S	*	*	H	α-helix	trans	-66.1	-35.9	171.5	-96	177.4	-4	0	0	112.6	S450 V458	S450-Q454 WeakPolarHBondContact O-CB 3.38Å; S450-Q454 PolarHBondContact O-N 2.81Å; Q454-V458 WeakPolarHBondContact O-CG2 3.49Å
455	G	55.8	Low	58.3	Low	51 Å²	51	120.6 Å²	120.6	53%	0.526	66%	0.664	S	S	.	*	H	α-helix	trans	-68	-36.1	175.5	0	0	0	0	0	113.2	K451 D452	K451-G455 PolarHBondContact O-N 3.44Å; D452-G455 PolarHBondContact O-N 3.37Å
456	S	54.8	Low	56.1	Low	91 Å²	91	119.1 Å²	119.1	64%	0.636	67%	0.669	S	S	*	*	H	α-helix	trans	-76.8	-30	178.7	-164.9	0	0	0	0	113.4	D452 D453 V458 G459	D452-S456 PolarHBondContact O-N 3.1Å; D453-S456 PolarHBondContact O-N 2.97Å; S456-V458 VanDerWaalsContact C-N 3.3Å; S456-G459 PolarHBondContact O-N 3.46Å
457	A	52.2	Low	53.7	Low	84 Å²	84	116.3 Å²	116.3	69%	0.694	67%	0.674	S	S	*	*	H	α-helix	trans	-71.1	-24.7	176.1	0	0	0	0	0	113.1	D453	D453-A457 PolarHBondContact O-N 3.32Å; D453-A457 VanDerWaalsContact O-N 3.11Å
458	V	54.7	Low	51.4	Low	128 Å²	128	118 Å²	118	78%	0.776	69%	0.689	S	S	*	*	S	Bend	trans	-85.9	-12.8	178.6	177.1	0	0	0	0	112.2	Q454 S456	Q454-V458 WeakPolarHBondContact O-CG2 3.49Å; S456-V458 VanDerWaalsContact C-N 3.3Å
459	G	45.7	Very low	49.4	Very low	64 Å²	64	120.2 Å²	120.2	66%	0.66	70%	0.704	S	S	*	*	S	Bend	trans	-89.8	-1.4	-174.3	0	0	0	0	0	116.9	S456	S456-G459 PolarHBondContact O-N 3.46Å
460	N	44.4	Very low	47.4	Very low	161 Å²	161	122.9 Å²	122.9	86%	0.861	72%	0.717	S	S	*	*	S	Bend	trans	-128.9	26.1	-167.9	-139.6	31.4	0	0	0	115.7
461	G	40.4	Very low	45.6	Very low	63 Å²	63	126.4 Å²	126.4	65%	0.649	73%	0.731	S	S	*	*			trans	-139.7	67.5	-179.9	0	0	0	0	0	112.7
462	D	42	Very low	43.7	Very low	161 Å²	161	125.7 Å²	125.7	86%	0.861	73%	0.734	S	S	*	*			trans	-153	87.3	162.8	-93.4	-33.8	0	0	0	111.5
463	Q	34.5	Very low	41.8	Very low	201 Å²	201	128.2 Å²	128.2	94%	0.939	75%	0.746	S	S	*	*			trans	-147.7	99.3	151.6	-107.7	171.3	26.3	0	0	108.9
464	H	33.1	Very low	40.1	Very low	156 Å²	156	131.3 Å²	131.3	72%	0.722	76%	0.757	S	S	*	*			trans	-69	173.5	168.2	-124.9	-76.6	0	0	0	110.6
465	P	48.1	Very low	39.7	Very low	101 Å²	101	130 Å²	130	66%	0.656	76%	0.761	S	S	*	*			cis	-145.6	164.3	5.5	38.6	-16.9	0	0	0	120.4
466	L	31.7	Very low	38.4	Very low	161 Å²	161	130.8 Å²	130.8	84%	0.843	77%	0.769	S	S	*	*			trans	51.5	125.2	138.1	-67.9	162.4	0	0	0	122.5
467	G	29.1	Very low	37.2	Very low	66 Å²	66	133.6 Å²	133.6	68%	0.68	78%	0.782	S	S	*	*			trans	175.4	96.7	154.3	0	0	0	0	0	110.5
468	L	30.9	Very low	36.2	Very low	182 Å²	182	134 Å²	134	95%	0.953	79%	0.786	S	S	*	*				80.5	113.5	107.5	-89.4	155.3	0	0	0	114.6
469	D	34.8	Very low	35.2	Very low	156 Å²	156	137.6 Å²	137.6	83%	0.834	79%	0.794	S	S	*	*			trans	-66.4	146.7	174	-66.3	-58.5	0	0	0	112.9
470	E	32.1	Very low	34.6	Very low	183 Å²	183	138.3 Å²	138.3	86%	0.855	80%	0.802	S	S	*	*			trans	-162.9	110.3	144.8	-116.2	177.1	137.4	0	0	112
471	D	32.5	Very low	34.2	Very low	136 Å²	136	140.3 Å²	140.3	73%	0.727	81%	0.806	S	S	*	*				54.1	122.2	129.6	-76.7	-15.3	0	0	0	124.7
472	L	30.3	Very low	33.9	Very low	139 Å²	139	140.7 Å²	140.7	73%	0.728	81%	0.81	S	S	*	*				87.8	132.7	122.6	-78.1	167.2	0	0	0	122.8
473	L	29.9	Very low	34.2	Very low	158 Å²	158	139.1 Å²	139.1	83%	0.827	81%	0.808	S	S	*	*			trans	102.4	97.5	145.8	-68.7	148.8	0	0	0	120
474	E	27.1	Very low	35.1	Very low	174 Å²	174	135.4 Å²	135.4	81%	0.813	80%	0.801	S	S	*	*			trans	-71.8	179.9	143	-112.8	-163.2	172.8	0	0	111.1
475	P	49	Very low	35.5	Very low	114 Å²	114	134.1 Å²	134.1	74%	0.74	81%	0.805	S	S	*	*			cis	-138.5	178.1	-16.9	29.5	-7.7	0	0	0	114
476	G	28.3	Very low	36.2	Very low	67 Å²	67	135.3 Å²	135.3	69%	0.691	81%	0.813	S	S	*	*			trans	166.7	89.9	154.1	0	0	0	0	0	119.7
477	V	30.6	Very low	36.7	Very low	150 Å²	150	139.1 Å²	139.1	91%	0.909	83%	0.834	S	S	*	*			trans	64.5	116.6	137.8	-166.4	0	0	0	0	120.3
478	A	31.3	Very low	37.1	Very low	94 Å²	94	142.8 Å²	142.8	78%	0.777	84%	0.841	S	S	*	*				167.9	119.2	107.5	0	0	0	0	0	112.2
479	E	34.3	Very low	37.5	Very low	202 Å²	202	140.7 Å²	140.7	94%	0.944	84%	0.835	S	S	*	*			trans	-74.6	153.7	165.1	-71.2	179.1	129.9	0	0	111.8
480	G	32.5	Very low	37.6	Very low	80 Å²	80	139.8 Å²	139.8	83%	0.825	84%	0.836	S	S	*	*			trans	-151.8	110.7	166.9	0	0	0	0	0	110.8
481	E	34.9	Very low	37.9	Very low	203 Å²	203	137.3 Å²	137.3	95%	0.949	83%	0.834	S	S	*	*			trans	-73.6	146	-178.7	-72	180	121.1	0	0	115
482	G	34.5	Very low	38.3	Very low	71 Å²	71	137.4 Å²	137.4	73%	0.732	84%	0.841	S	S	*	*			trans	86.6	173.9	136.3	0	0	0	0	0	118.6
483	P	48	Very low	38.8	Very low	128 Å²	128	137.3 Å²	137.3	83%	0.831	85%	0.849	S	S	*	*			cis	-133.5	-173.4	-22.4	39.7	-21.1	0	0	0	112.2
484	P	53.7	Low	39.4	Very low	122 Å²	122	135.8 Å²	135.8	79%	0.792	85%	0.85	S	S	*	*			trans	-104.4	176.5	-151.9	36.3	-27.8	0	0	0	117.9
485	T	42.4	Very low	40.4	Very low	130 Å²	130	132.8 Å²	132.8	80%	0.798	85%	0.853	S	S	*	*			trans	-45.9	149	175.9	47.5	0	0	0	0	117.3
486	P	62.3	Low	39.7	Very low	126 Å²	126	134.4 Å²	134.4	82%	0.818	86%	0.862	S	S	*	*			trans	-104.5	157.1	158.5	35.1	-23.4	0	0	0	113.2
487	N	43.1	Very low	40.7	Very low	240 Å²	240	140.5 Å²	140.5	100%	1.283	88%	0.878	S	S	*	*			trans	-53.7	0	176	-73.1	-37.5	0	0	0	115.5

Retrieved 487 of 487 residues in 1210.8 ms (Link to these results)

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