A0A096N2K5_PAPAN Loading...

Tyrosine-protein phosphatase non-receptor type

AlphaFold DB (A0A2K6AZ82), UniProt , Accession A0A096N2K5, Species PAPAN (Papio anubis, Olive baboon), Gene PTPN11, Length 597 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M52.8Low76.7Confident74 Ų7438.8 Ų38.837%0.36521%0.21SC..  0126.70-168.3-167.3-76.900108.3W6 F29 V78 M82 P101 L262M1-W6 PolarHBondContact SD-NE1 3.26Å; M1-F29 HydrophobicContact CE-CZ 4.38Å; M1-V78 HydrophobicContact CE-CG1 3.79Å; M1-V78 HydrophobicContact SD-CG1 4.35Å; M1-M82 HydrophobicContact CE-CE 3.64Å; M1-M82 HydrophobicContact CE-SD 2.96Å; M1-M82 WeakPolarHBondContact CE-SD 3.44Å; M1-P101 HydrophobicContact CE-CG 4.41Å; M1-L262 WeakPolarHBondContact O-CD1 3.47Å
2T55.6Low77.9Confident133 Ų13338.2 Ų38.282%0.81621%0.209SC*.  trans-102.1-5.3-170.648.30000114.5
3S69.6Low79Confident51 Ų5136.7 Ų36.736%0.35721%0.208SC..  trans-137.6139.2-175.4-178.90000111.7R5S3-R5 VanDerWaalsContact C-N 3.28Å; S3-R5 PolarHBondContact O-N 3.18Å; S3-R5 WeakPolarHBondContact OG-CG 3.29Å
4R80.8Confident80.1Confident2 Ų240.8 Ų40.81%0.00823%0.233CC..  trans-89.720.5-179.1-154.2-168.9-175.9-134.75.9113W6 F7 E252 Q255 E258R4-W6 HydrophobicContact CG-CH2 3.93Å; R4-W6 HydrophobicContact CG-CZ2 3.53Å; R4-W6 PolarHBondContact O-N 3.16Å; R4-F7 HydrophobicContact CG-CB 4.27Å; R4-F7 WeakPolarHBondContact O-CB 3.36Å; R4-F7 PolarHBondContact O-N 3.17Å; R4-E252 IonicContact NH1-OE2 3.27Å; R4-E252 PolarHBondContact NH1-OE2 2.97Å; R4-Q255 WeakPolarHBondContact CD-O 3.17Å; R4-Q255 VanDerWaalsContact NH1-CB 3.28Å; R4-E258 IonicContact CZ-OE1 3.8Å; R4-E258 IonicContact NE-OE1 2.95Å; R4-E258 PolarHBondContact NE-OE1 2.98Å; R4-E258 IonicContact NH2-OE1 2.62Å; R4-E258 PolarHBondContact NH2-OE1 2.89Å
5R78.6Confident81Confident74 Ų7444.2 Ų44.228%0.27925%0.247SC..THydrogen-bonded Turntrans-60.6-16.1-175.7-79.4-166.1-56-167.87114.8S3 F7 N103 C104 D192S3-R5 VanDerWaalsContact C-N 3.28Å; S3-R5 PolarHBondContact O-N 3.18Å; S3-R5 WeakPolarHBondContact OG-CG 3.29Å; R5-F7 PolarHBondContact O-N 2.87Å; R5-N103 HydrophobicContact CB-CB 3.89Å; R5-N103 VanDerWaalsContact CB-OD1 3.28Å; R5-N103 WeakPolarHBondContact CB-OD1 3.37Å; R5-N103 CarbonylContact O-C 3.59Å; R5-N103 WeakPolarHBondContact O-CA 3.48Å; R5-C104 WeakPolarHBondContact O-CB 3.2Å; R5-C104 PolarHBondContact O-N 2.85Å; R5-D192 IonicContact CZ-OD1 3.44Å; R5-D192 IonicContact NH1-OD1 3.51Å; R5-D192 PolarHBondContact NH1-OD1 2.86Å
6W86.3Confident81.8Confident1 Ų141.4 Ų41.40%0.00423%0.231CC..THydrogen-bonded Turntrans-70.2-7.9172.548-94.6000114M1 R4 H8 F29 L30 A31 L74 A75 V78 P101M1-W6 PolarHBondContact SD-NE1 3.26Å; R4-W6 HydrophobicContact CG-CH2 3.93Å; R4-W6 HydrophobicContact CG-CZ2 3.53Å; R4-W6 PolarHBondContact O-N 3.16Å; W6-H8 PolarHBondContact O-CD2 2.81Å; W6-F29 HydrophobicContact CB-CE2 4.05Å; W6-F29 HydrophobicContact CD2-CE2 4.49Å; W6-F29 HydrophobicContact CG-CE2 4.17Å; W6-L30 WeakPolarHBondContact O-CA 3.43Å; W6-A31 HydrophobicContact CE3-CB 3.58Å; W6-A31 HydrophobicContact CZ3-CB 3.51Å; W6-A31 PolarHBondContact O-N 3.23Å; W6-L74 HydrophobicContact CH2-CB 3.75Å; W6-L74 HydrophobicContact CZ3-CB 4.25Å; W6-A75 HydrophobicContact CZ2-CB 4.25Å; W6-V78 HydrophobicContact CD2-CG1 4.37Å; W6-V78 HydrophobicContact CD2-CG2 4.14Å; W6-V78 HydrophobicContact CE3-CG2 3.9Å; W6-V78 HydrophobicContact CH2-CB 4.33Å; W6-V78 HydrophobicContact CH2-CG2 3.71Å; W6-V78 HydrophobicContact CZ2-CB 4.1Å; W6-V78 HydrophobicContact CZ2-CG1 4.46Å; W6-V78 HydrophobicContact CZ2-CG2 3.93Å; W6-V78 HydrophobicContact CZ3-CG2 3.68Å; W6-P101 HydrophobicContact CB-CB 3.7Å; W6-P101 HydrophobicContact CG-CB 4.31Å
7F86.7Confident82.7Confident3 Ų343.3 Ų43.31%0.01324%0.238CC..BIsolated β-bridgetrans-90.5126.1175.4-172-96.9000110.9R4 R5 P9 A31 P33 F41 L74 C104 E252R4-F7 HydrophobicContact CG-CB 4.27Å; R4-F7 WeakPolarHBondContact O-CB 3.36Å; R4-F7 PolarHBondContact O-N 3.17Å; R5-F7 PolarHBondContact O-N 2.87Å; F7-P9 HydrophobicContact CE1-CB 4.23Å; F7-A31 CarbonylContact C-O 3.46Å; F7-A31 WeakPolarHBondContact CA-O 3.32Å; F7-A31 HydrophobicContact CD2-CB 4Å; F7-P33 HydrophobicContact CZ-CG 3.9Å; F7-F41 AromaticContact CE2-CD1 3.83Å; F7-F41 HydrophobicContact CE2-CD1 3.83Å; F7-F41 HydrophobicContact CE2-CE1 4.03Å; F7-F41 HydrophobicContact CZ-CD1 4.14Å; F7-F41 AromaticContact CZ-CE1 3.97Å; F7-F41 HydrophobicContact CZ-CE1 3.97Å; F7-L74 HydrophobicContact CD2-CD1 4.19Å; F7-L74 HydrophobicContact CE2-CD1 3.87Å; F7-C104 WeakPolarHBondContact O-CB 3.41Å; F7-E252 WeakPolarHBondContact CE1-OE2 3.3Å; F7-E252 WeakPolarHBondContact CZ-OE2 3.38Å
8H87Confident83.3Confident7 Ų745.8 Ų45.83%0.03225%0.251CS..  trans-114.5106.7179.9-66.6-115000109.3W6 N10 I11 A31 R32 P33 L102 C104W6-H8 PolarHBondContact O-CD2 2.81Å; H8-N10 PolarHBondContact O-N 2.64Å; H8-I11 HydrophobicContact CB-CD1 3.4Å; H8-I11 VanDerWaalsContact CB-CD1 3.4Å; H8-I11 HydrophobicContact CB-CG1 3.58Å; H8-I11 HydrophobicContact CB-CG2 4.21Å; H8-A31 PolarHBondContact N-O 2.97Å; H8-R32 WeakPolarHBondContact O-CA 3.36Å; H8-R32 WeakPolarHBondContact O-CB 3.36Å; H8-P33 WeakPolarHBondContact O-CD 2.89Å; H8-L102 PolarHBondContact NE2-O 3.11Å; H8-C104 WeakPolarHBondContact CE1-CA 3.39Å; H8-C104 PolarHBondContact ND1-SG 3.33Å
9P79.6Confident83.7Confident6 Ų645.4 Ų45.44%0.03925%0.248CC..SBendtrans-69.3-32.8-171.422.9-30.9000113.6F7 P33 W248F7-P9 HydrophobicContact CE1-CB 4.23Å; P9-P33 WeakPolarHBondContact O-CG 3.3Å; P9-W248 HydrophobicContact CB-CH2 3.64Å; P9-W248 HydrophobicContact CB-CZ2 4.49Å; P9-W248 HydrophobicContact CB-CZ3 4.39Å; P9-W248 WeakPolarHBondContact O-CH2 3.21Å
10N81.3Confident84.2Confident51 Ų5143.2 Ų43.227%0.27324%0.236SC..SBendtrans-115.15.5-162-65.9-40.2000115.7H8 D106 T108H8-N10 PolarHBondContact O-N 2.64Å; N10-D106 PolarHBondContact ND2-OD2 3.44Å; N10-T108 PolarHBondContact ND2-OG1 2.71Å
11I85.8Confident84.7Confident25 Ų2544.7 Ų44.713%0.12824%0.243CC..  trans-95.2148.9-173.970.4173.6000113.7H8 E15 A16 L19 L30 R32H8-I11 HydrophobicContact CB-CD1 3.4Å; H8-I11 VanDerWaalsContact CB-CD1 3.4Å; H8-I11 HydrophobicContact CB-CG1 3.58Å; H8-I11 HydrophobicContact CB-CG2 4.21Å; I11-E15 HydrophobicContact CB-CB 4.22Å; I11-A16 HydrophobicContact CD1-CB 3.83Å; I11-L19 HydrophobicContact CD1-CD1 4.23Å; I11-L30 HydrophobicContact CD1-CD1 3.8Å; I11-L30 HydrophobicContact CD1-CD2 4.06Å; I11-R32 HydrophobicContact CD1-CB 4.49Å; I11-R32 HydrophobicContact CG1-CB 3.99Å
12T91.5Very high86.5Confident31 Ų3146.3 Ų46.319%0.1926%0.258CS..  trans-78.4173.1170.5620000112E15 A16 K35T12-E15 VanDerWaalsContact CB-OE2 3.31Å; T12-E15 WeakPolarHBondContact CB-OE2 3.48Å; T12-E15 VanDerWaalsContact CG2-OE2 3.26Å; T12-E15 WeakPolarHBondContact CG2-OE2 3.39Å; T12-E15 PolarHBondContact N-OE2 3.12Å; T12-E15 WeakPolarHBondContact OG1-CB 3.49Å; T12-E15 VanDerWaalsContact OG1-CD 3.28Å; T12-E15 VanDerWaalsContact OG1-CG 3.23Å; T12-E15 WeakPolarHBondContact OG1-CG 3.44Å; T12-E15 PolarHBondContact OG1-N 2.72Å; T12-E15 PolarHBondContact OG1-OE2 2.85Å; T12-A16 WeakPolarHBondContact O-CB 3.34Å; T12-A16 PolarHBondContact O-N 2.86Å; T12-A16 VanDerWaalsContact O-N 3.11Å; T12-K35 HydrophobicContact CG2-CD 3.78Å; T12-K35 VanDerWaalsContact CG2-CE 3.48Å
13G91.8Very high88Confident19 Ų1948.7 Ų48.720%0.19625%0.252CS..Hα-helixtrans-62.1-45.2168.700000113E15 A16 E17 R32G13-E15 PolarHBondContact O-N 2.84Å; G13-A16 WeakPolarHBondContact O-CB 3.09Å; G13-A16 PolarHBondContact O-N 2.89Å; G13-E17 WeakPolarHBondContact O-CG 3.5Å; G13-E17 PolarHBondContact O-N 2.81Å; G13-R32 VanDerWaalsContact CA-CZ 3.45Å
14V94.9Very high89Confident94 Ų9446.8 Ų46.857%0.5724%0.24SC*.Hα-helixtrans-64.1-43.4-179.7-178.50000111.5A16 E17 N18V14-A16 VanDerWaalsContact C-N 3.32Å; V14-A16 PolarHBondContact O-N 2.95Å; V14-E17 PolarHBondContact O-N 2.92Å; V14-N18 PolarHBondContact O-N 3.43Å; V14-N18 PolarHBondContact O-ND2 2.91Å
15E92.9Very high89.6Confident92 Ų9250.5 Ų50.543%0.4326%0.262SS..Hα-helixtrans-63.9-38175-71.5160.2147.900111.8I11 T12 G13 N18 L19I11-E15 HydrophobicContact CB-CB 4.22Å; T12-E15 VanDerWaalsContact CB-OE2 3.31Å; T12-E15 WeakPolarHBondContact CB-OE2 3.48Å; T12-E15 VanDerWaalsContact CG2-OE2 3.26Å; T12-E15 WeakPolarHBondContact CG2-OE2 3.39Å; T12-E15 PolarHBondContact N-OE2 3.12Å; T12-E15 WeakPolarHBondContact OG1-CB 3.49Å; T12-E15 VanDerWaalsContact OG1-CD 3.28Å; T12-E15 VanDerWaalsContact OG1-CG 3.23Å; T12-E15 WeakPolarHBondContact OG1-CG 3.44Å; T12-E15 PolarHBondContact OG1-N 2.72Å; T12-E15 PolarHBondContact OG1-OE2 2.85Å; G13-E15 PolarHBondContact O-N 2.84Å; E15-N18 PolarHBondContact O-N 2.96Å; E15-L19 WeakPolarHBondContact O-CB 3.31Å; E15-L19 VanDerWaalsContact O-CG 3.3Å; E15-L19 WeakPolarHBondContact O-CG 3.34Å; E15-L19 PolarHBondContact O-N 3.26Å
16A94.2Very high90.3Very high0 Ų050.2 Ų50.20%027%0.267CS..Hα-helixtrans-63.6-43.4174.900000112.4I11 T12 G13 V14 L19 L20 L30I11-A16 HydrophobicContact CD1-CB 3.83Å; T12-A16 WeakPolarHBondContact O-CB 3.34Å; T12-A16 PolarHBondContact O-N 2.86Å; T12-A16 VanDerWaalsContact O-N 3.11Å; G13-A16 WeakPolarHBondContact O-CB 3.09Å; G13-A16 PolarHBondContact O-N 2.89Å; V14-A16 VanDerWaalsContact C-N 3.32Å; V14-A16 PolarHBondContact O-N 2.95Å; A16-L19 PolarHBondContact O-N 3.11Å; A16-L20 WeakPolarHBondContact O-CB 3.32Å; A16-L20 WeakPolarHBondContact O-CG 3.4Å; A16-L20 PolarHBondContact O-N 2.97Å; A16-L30 HydrophobicContact CB-CD1 3.91Å; A16-L30 HydrophobicContact CB-CD2 4.3Å
17E96.1Very high90.6Very high73 Ų7350.5 Ų50.534%0.34127%0.269SS..Hα-helixtrans-59.6-50.4174.8-70.7178.9-178.100110.8G13 V14 L19 L20 L21 V51 H53G13-E17 WeakPolarHBondContact O-CG 3.5Å; G13-E17 PolarHBondContact O-N 2.81Å; V14-E17 PolarHBondContact O-N 2.92Å; E17-L19 VanDerWaalsContact C-N 3.34Å; E17-L19 PolarHBondContact O-N 2.76Å; E17-L20 PolarHBondContact O-N 2.91Å; E17-L21 WeakPolarHBondContact O-CB 3.29Å; E17-L21 VanDerWaalsContact O-CG 3.29Å; E17-L21 WeakPolarHBondContact O-CG 3.29Å; E17-L21 PolarHBondContact O-N 3.08Å; E17-V51 HydrophobicContact CG-CB 4.01Å; E17-V51 HydrophobicContact CG-CG1 3.93Å; E17-H53 WeakPolarHBondContact CG-NE2 3.36Å; E17-H53 IonicContact OE1-CD2 3.75Å; E17-H53 IonicContact OE1-NE2 2.97Å; E17-H53 PolarHBondContact OE1-NE2 3.45Å
18N94.2Very high91Very high89 Ų8950.7 Ų50.748%0.47627%0.271SS..Hα-helixtrans-58-44.9178.2-72.9-22.1000112.1V14 E15 L21 T22V14-N18 PolarHBondContact O-N 3.43Å; V14-N18 PolarHBondContact O-ND2 2.91Å; E15-N18 PolarHBondContact O-N 2.96Å; N18-L21 PolarHBondContact O-N 2.99Å; N18-T22 WeakPolarHBondContact O-CB 3.33Å; N18-T22 VanDerWaalsContact O-CG2 3.31Å; N18-T22 WeakPolarHBondContact O-CG2 3.14Å; N18-T22 PolarHBondContact O-N 2.87Å; N18-T22 PolarHBondContact O-OG1 2.82Å
19L90.1Very high91.5Very high38 Ų3850.3 Ų50.320%0.19927%0.27CS..Hα-helixtrans-62.2-45.8177.2-77.3170.2000112I11 E15 A16 E17 R23 G24 L102I11-L19 HydrophobicContact CD1-CD1 4.23Å; E15-L19 WeakPolarHBondContact O-CB 3.31Å; E15-L19 VanDerWaalsContact O-CG 3.3Å; E15-L19 WeakPolarHBondContact O-CG 3.34Å; E15-L19 PolarHBondContact O-N 3.26Å; A16-L19 PolarHBondContact O-N 3.11Å; E17-L19 VanDerWaalsContact C-N 3.34Å; E17-L19 PolarHBondContact O-N 2.76Å; L19-R23 WeakPolarHBondContact O-CB 3.38Å; L19-R23 PolarHBondContact O-N 2.84Å; L19-G24 PolarHBondContact O-N 3.3Å; L19-L102 HydrophobicContact CB-CD2 4.38Å
20L93.6Very high92.2Very high0 Ų050 Ų500%027%0.268CS..Hα-helixtrans-66.8-38179.9-76.7167000112.4A16 E17 G24 L30 R46 V51 L102A16-L20 WeakPolarHBondContact O-CB 3.32Å; A16-L20 WeakPolarHBondContact O-CG 3.4Å; A16-L20 PolarHBondContact O-N 2.97Å; E17-L20 PolarHBondContact O-N 2.91Å; L20-G24 CarbonylContact O-C 3.5Å; L20-G24 WeakPolarHBondContact O-CA 3.5Å; L20-G24 PolarHBondContact O-N 3.44Å; L20-L30 HydrophobicContact CD1-CD2 4.38Å; L20-L30 HydrophobicContact CD1-CG 4.31Å; L20-L30 HydrophobicContact CD2-CD2 4.44Å; L20-L30 HydrophobicContact CG-CD2 4.09Å; L20-L30 HydrophobicContact CG-CG 4.44Å; L20-R46 HydrophobicContact CB-CB 4.31Å; L20-R46 HydrophobicContact CD2-CB 4.38Å; L20-R46 WeakPolarHBondContact O-CD 3.46Å; L20-R46 PolarHBondContact O-NH1 2.84Å; L20-V51 HydrophobicContact CB-CG2 3.83Å; L20-V51 HydrophobicContact CD1-CG1 3.71Å; L20-V51 HydrophobicContact CD1-CG2 4.16Å; L20-L102 HydrophobicContact CD2-CB 4.38Å; L20-L102 HydrophobicContact CD2-CD1 3.93Å; L20-L102 HydrophobicContact CG-CD1 4.45Å
21L94.5Very high92.7Very high75 Ų7547.7 Ų47.739%0.39326%0.256SS..Hα-helixtrans-74.3-38.8179.6-69.9173.1000112.6E17 N18 R46 G49 V51E17-L21 WeakPolarHBondContact O-CB 3.29Å; E17-L21 VanDerWaalsContact O-CG 3.29Å; E17-L21 WeakPolarHBondContact O-CG 3.29Å; E17-L21 PolarHBondContact O-N 3.08Å; N18-L21 PolarHBondContact O-N 2.99Å; L21-R46 PolarHBondContact O-NH1 3.1Å; L21-G49 WeakPolarHBondContact CD2-O 3.38Å; L21-V51 HydrophobicContact CD2-CG2 4.14Å; L21-V51 HydrophobicContact CG-CG2 4.02Å
22T90.9Very high93.1Very high109 Ų10947.3 Ų47.367%0.66925%0.252SS*.Hα-helixtrans-86.8-35.8-176.857.90000114.1N18N18-T22 WeakPolarHBondContact O-CB 3.33Å; N18-T22 VanDerWaalsContact O-CG2 3.31Å; N18-T22 WeakPolarHBondContact O-CG2 3.14Å; N18-T22 PolarHBondContact O-N 2.87Å; N18-T22 PolarHBondContact O-OG1 2.82Å
23R88.3Confident93Very high183 Ų18346 Ų4669%0.69125%0.245SC*.Hα-helixtrans-114.3-20.3-175-57.6-177.1-177-170.2-0.6113.9L19 L102L19-R23 WeakPolarHBondContact O-CB 3.38Å; L19-R23 PolarHBondContact O-N 2.84Å; R23-L102 HydrophobicContact CB-CD1 4.36Å
24G90.1Very high92.9Very high10 Ų1045.3 Ų45.310%0.10324%0.236CC..  trans-87.9175.4179.800000113.3L19 L20 S28 R46L19-G24 PolarHBondContact O-N 3.3Å; L20-G24 CarbonylContact O-C 3.5Å; L20-G24 WeakPolarHBondContact O-CA 3.5Å; L20-G24 PolarHBondContact O-N 3.44Å; G24-S28 WeakPolarHBondContact CA-OG 3.2Å; G24-R46 PolarHBondContact O-NH1 2.86Å
25V92.6Very high92.5Very high80 Ų8047 Ų4749%0.48524%0.236SC..  trans-128.5174.3167.9-64.20000108.9G27 S28 R46 Y100V25-G27 PolarHBondContact O-N 2.87Å; V25-S28 PolarHBondContact N-OG 2.81Å; V25-S28 WeakPolarHBondContact O-CA 3.38Å; V25-S28 WeakPolarHBondContact O-CB 3.22Å; V25-S28 PolarHBondContact O-N 2.84Å; V25-S28 PolarHBondContact O-OG 2.82Å; V25-S28 VanDerWaalsContact O-OG 3.12Å; V25-R46 WeakPolarHBondContact O-CD 3.38Å; V25-Y100 HydrophobicContact CG2-CD2 3.53Å; V25-Y100 HydrophobicContact CG2-CE2 3.78Å; V25-Y100 HydrophobicContact CG2-CG 4.37Å
26D94.3Very high92.3Very high69 Ų6948.1 Ų48.137%0.36925%0.254SS..THydrogen-bonded Turntrans-61.8131.6176-73.35.9000110.8R46 N48 G49D26-R46 WeakPolarHBondContact OD1-CG 3.4Å; D26-R46 IonicContact OD1-NE 3.11Å; D26-R46 PolarHBondContact OD1-NE 2.83Å; D26-R46 VanDerWaalsContact OD1-NE 3.11Å; D26-N48 VanDerWaalsContact OD2-CA 3.29Å; D26-N48 WeakPolarHBondContact OD2-CA 3.23Å; D26-N48 PolarHBondContact OD2-N 3.34Å; D26-G49 PolarHBondContact OD1-N 3.49Å; D26-G49 PolarHBondContact OD2-N 3.24Å
27G91.9Very high91.9Very high6 Ų651.3 Ų51.36%0.06227%0.271CS..THydrogen-bonded Turntrans87.9-3.3-167.400000114.4V25 R46 K99 Y100V25-G27 PolarHBondContact O-N 2.87Å; G27-R46 PolarHBondContact N-O 3.48Å; G27-K99 PolarHBondContact O-N 3.42Å; G27-Y100 PolarHBondContact O-N 2.87Å
28S95.1Very high91.3Very high7 Ų752.8 Ų52.85%0.04929%0.287CS..EExtended strand (participates in β ladder)trans-68.8140.7169.6-71.90000111.3G24 V25 R46 Y100G24-S28 WeakPolarHBondContact CA-OG 3.2Å; V25-S28 PolarHBondContact N-OG 2.81Å; V25-S28 WeakPolarHBondContact O-CA 3.38Å; V25-S28 WeakPolarHBondContact O-CB 3.22Å; V25-S28 PolarHBondContact O-N 2.84Å; V25-S28 PolarHBondContact O-OG 2.82Å; V25-S28 VanDerWaalsContact O-OG 3.12Å; S28-R46 PolarHBondContact O-N 2.77Å; S28-Y100 CarbonylContact C-O 3.58Å; S28-Y100 WeakPolarHBondContact CA-O 3.41Å
29F96.9Very high90.7Very high0 Ų051.1 Ų51.10%029%0.291CS..EExtended strand (participates in β ladder)trans-145158.4179.973.8-84.9000112.6M1 W6 L43 S44 V45 V78 M82 L98 Y100 P101 L102M1-F29 HydrophobicContact CE-CZ 4.38Å; W6-F29 HydrophobicContact CB-CE2 4.05Å; W6-F29 HydrophobicContact CD2-CE2 4.49Å; W6-F29 HydrophobicContact CG-CE2 4.17Å; F29-L43 HydrophobicContact CB-CD1 4.46Å; F29-L43 HydrophobicContact CD2-CD1 3.87Å; F29-S44 CarbonylContact C-O 3.51Å; F29-S44 VanDerWaalsContact CA-O 3.23Å; F29-S44 WeakPolarHBondContact CA-O 3.4Å; F29-V45 HydrophobicContact CB-CB 4.41Å; F29-V45 HydrophobicContact CB-CG1 4.25Å; F29-V45 HydrophobicContact CB-CG2 4.04Å; F29-V78 HydrophobicContact CE2-CG1 3.57Å; F29-V78 HydrophobicContact CE2-CG2 4.19Å; F29-V78 HydrophobicContact CZ-CG1 3.57Å; F29-M82 HydrophobicContact CE1-CE 4.37Å; F29-M82 HydrophobicContact CE1-CG 4.2Å; F29-M82 HydrophobicContact CE1-SD 3.63Å; F29-M82 HydrophobicContact CZ-CG 4.24Å; F29-M82 HydrophobicContact CZ-SD 3.44Å; F29-M82 WeakPolarHBondContact CZ-SD 3.39Å; F29-L98 HydrophobicContact CB-CD2 3.86Å; F29-L98 HydrophobicContact CD1-CB 3.84Å; F29-L98 HydrophobicContact CD1-CD2 4.2Å; F29-L98 HydrophobicContact CD2-CD2 4.42Å; F29-L98 HydrophobicContact CE1-CB 3.95Å; F29-L98 HydrophobicContact CG-CB 4.34Å; F29-L98 HydrophobicContact CG-CD2 3.9Å; F29-Y100 PolarHBondContact N-O 2.81Å; F29-P101 HydrophobicContact CE1-CB 4.08Å; F29-P101 HydrophobicContact CE2-CB 4.46Å; F29-P101 HydrophobicContact CZ-CB 3.82Å; F29-L102 PolarHBondContact O-N 3.05Å
30L94.6Very high90.7Very high0 Ų049.8 Ų49.80%028%0.284CS..EExtended strand (participates in β ladder)trans-146.3154.9168.662.781.1000110.2W6 I11 A16 L20 R32 S44 L102W6-L30 WeakPolarHBondContact O-CA 3.43Å; I11-L30 HydrophobicContact CD1-CD1 3.8Å; I11-L30 HydrophobicContact CD1-CD2 4.06Å; A16-L30 HydrophobicContact CB-CD1 3.91Å; A16-L30 HydrophobicContact CB-CD2 4.3Å; L20-L30 HydrophobicContact CD1-CD2 4.38Å; L20-L30 HydrophobicContact CD1-CG 4.31Å; L20-L30 HydrophobicContact CD2-CD2 4.44Å; L20-L30 HydrophobicContact CG-CD2 4.09Å; L20-L30 HydrophobicContact CG-CG 4.44Å; L30-R32 HydrophobicContact CD1-CB 4.41Å; L30-R32 HydrophobicContact CD1-CG 4.31Å; L30-S44 PolarHBondContact N-O 2.92Å; L30-S44 PolarHBondContact O-N 3.39Å; L30-L102 HydrophobicContact CD2-CD2 4.16Å
31A93.2Very high90.7Very high2 Ų250.5 Ų50.52%0.01729%0.287CS..EExtended strand (participates in β ladder)trans-109.9147.1170.400000109.8W6 F7 H8 T42W6-A31 HydrophobicContact CE3-CB 3.58Å; W6-A31 HydrophobicContact CZ3-CB 3.51Å; W6-A31 PolarHBondContact O-N 3.23Å; F7-A31 CarbonylContact C-O 3.46Å; F7-A31 WeakPolarHBondContact CA-O 3.32Å; F7-A31 HydrophobicContact CD2-CB 4Å; H8-A31 PolarHBondContact N-O 2.97Å; A31-T42 WeakPolarHBondContact CA-O 3.17Å
32R92.4Very high90.7Very high16 Ų1647.5 Ų47.56%0.0627%0.272CS..EExtended strand (participates in β ladder)trans-148.4157.2178.758177.417873.40.6110.6H8 I11 G13 L30 F41 T42 S44 H53H8-R32 WeakPolarHBondContact O-CA 3.36Å; H8-R32 WeakPolarHBondContact O-CB 3.36Å; I11-R32 HydrophobicContact CD1-CB 4.49Å; I11-R32 HydrophobicContact CG1-CB 3.99Å; G13-R32 VanDerWaalsContact CA-CZ 3.45Å; L30-R32 HydrophobicContact CD1-CB 4.41Å; L30-R32 HydrophobicContact CD1-CG 4.31Å; R32-F41 CarbonylContact O-C 3.53Å; R32-F41 WeakPolarHBondContact O-CA 3.1Å; R32-T42 PolarHBondContact N-O 3.21Å; R32-T42 PolarHBondContact O-N 3Å; R32-S44 PolarHBondContact NE-OG 3.23Å; R32-H53 PolarHBondContact NH2-ND1 2.9Å
33P89.8Confident91Very high5 Ų542.3 Ų42.33%0.03224%0.24CC..EExtended strand (participates in β ladder)trans-59.8149.5166.8-22.233.8000112F7 H8 P9 W248F7-P33 HydrophobicContact CZ-CG 3.9Å; H8-P33 WeakPolarHBondContact O-CD 2.89Å; P9-P33 WeakPolarHBondContact O-CG 3.3Å; P33-W248 HydrophobicContact CG-CH2 4.47Å; P33-W248 HydrophobicContact CG-CZ2 3.75Å
34S90.4Very high91.4Very high3 Ų333.6 Ų33.62%0.02121%0.207CC..  trans-76.5131.4171.6-177.80000110.2S36 N37 D40S34-S36 PolarHBondContact OG-N 2.92Å; S34-S36 PolarHBondContact OG-OG 3.43Å; S34-N37 WeakPolarHBondContact CB-O 3.23Å; S34-N37 PolarHBondContact OG-N 2.65Å; S34-N37 VanDerWaalsContact OG-N 3.14Å; S34-D40 VanDerWaalsContact CB-O 3.23Å; S34-D40 WeakPolarHBondContact CB-O 3.19Å; S34-D40 PolarHBondContact N-O 3.38Å
35K86.3Confident91.7Very high131 Ų13133.1 Ų33.157%0.5720%0.202SC*.SBendtrans-86.2-27.4168.7-74-161.4177.6-1670112.4T12T12-K35 HydrophobicContact CG2-CD 3.78Å; T12-K35 VanDerWaalsContact CG2-CE 3.48Å
36S87.8Confident91.9Very high114 Ų11431.5 Ų31.580%0.79719%0.187SC*.SBendtrans-81.4-23.9-178.256.20000113.5S34S34-S36 PolarHBondContact OG-N 2.92Å; S34-S36 PolarHBondContact OG-OG 3.43Å
37N85.9Confident91.8Very high67 Ų6730.3 Ų30.336%0.35818%0.178SC..SBendtrans-140.796.1173.9-165.127.3000109.8S34 G39 D40S34-N37 WeakPolarHBondContact CB-O 3.23Å; S34-N37 PolarHBondContact OG-N 2.65Å; S34-N37 VanDerWaalsContact OG-N 3.14Å; N37-G39 PolarHBondContact O-N 3.45Å; N37-D40 HydrophobicContact CB-CB 4.37Å; N37-D40 PolarHBondContact ND2-OD2 3.01Å; N37-D40 WeakPolarHBondContact O-CB 3.17Å; N37-D40 PolarHBondContact O-N 3.08Å; N37-D40 VanDerWaalsContact O-N 3.15Å
38P84.1Confident91.8Very high105 Ų10536.4 Ų36.468%0.68221%0.209SC*.THydrogen-bonded Turntrans-53137.9177.4-26.935.6000112.2D40P38-D40 VanDerWaalsContact C-N 3.35Å
39G81.6Confident91.6Very high53 Ų5338 Ų3855%0.54623%0.227SC..THydrogen-bonded Turntrans92.9-22.9-174.200000114.6N37N37-G39 PolarHBondContact O-N 3.45Å
40D90.6Very high91.4Very high11 Ų1140.7 Ų40.76%0.05925%0.249CC..  trans-88.7167.1171.9-72.9-17.4000111.8S34 N37 P38 K55 I56 Q57 N58S34-D40 VanDerWaalsContact CB-O 3.23Å; S34-D40 WeakPolarHBondContact CB-O 3.19Å; S34-D40 PolarHBondContact N-O 3.38Å; N37-D40 HydrophobicContact CB-CB 4.37Å; N37-D40 PolarHBondContact ND2-OD2 3.01Å; N37-D40 WeakPolarHBondContact O-CB 3.17Å; N37-D40 PolarHBondContact O-N 3.08Å; N37-D40 VanDerWaalsContact O-N 3.15Å; P38-D40 VanDerWaalsContact C-N 3.35Å; D40-K55 WeakPolarHBondContact OD2-CE 3.38Å; D40-K55 IonicContact OD2-NZ 3.68Å; D40-K55 PolarHBondContact OD2-NZ 3.44Å; D40-I56 WeakPolarHBondContact CB-O 3.38Å; D40-Q57 WeakPolarHBondContact OD1-CA 3.38Å; D40-N58 PolarHBondContact OD1-N 3.5Å
41F93.2Very high91.5Very high14 Ų1441.9 Ų41.96%0.06126%0.256CS..EExtended strand (participates in β ladder)trans-124.3167.7177.2-55.1-94.2000110.9F7 R32 I56 N58 Y63 L74F7-F41 AromaticContact CE2-CD1 3.83Å; F7-F41 HydrophobicContact CE2-CD1 3.83Å; F7-F41 HydrophobicContact CE2-CE1 4.03Å; F7-F41 HydrophobicContact CZ-CD1 4.14Å; F7-F41 AromaticContact CZ-CE1 3.97Å; F7-F41 HydrophobicContact CZ-CE1 3.97Å; R32-F41 CarbonylContact O-C 3.53Å; R32-F41 WeakPolarHBondContact O-CA 3.1Å; F41-I56 HydrophobicContact CB-CB 4.03Å; F41-I56 HydrophobicContact CB-CD1 4.49Å; F41-I56 HydrophobicContact CB-CG2 4.44Å; F41-I56 PolarHBondContact N-O 2.91Å; F41-I56 PolarHBondContact O-N 3.18Å; F41-N58 HydrophobicContact CE2-CB 4.44Å; F41-Y63 HydrophobicContact CD2-CD1 4.26Å; F41-Y63 AromaticContact CD2-CE1 3.93Å; F41-Y63 HydrophobicContact CD2-CE1 3.93Å; F41-Y63 HydrophobicContact CE2-CD1 4.35Å; F41-Y63 AromaticContact CE2-CE1 3.61Å; F41-Y63 HydrophobicContact CE2-CE1 3.61Å; F41-Y63 HydrophobicContact CZ-CE1 4.27Å; F41-L74 HydrophobicContact CD1-CD1 3.9Å; F41-L74 HydrophobicContact CD2-CD1 4.47Å; F41-L74 HydrophobicContact CE1-CD1 4.12Å; F41-L74 HydrophobicContact CG-CD1 4.07Å
42T95.8Very high91.5Very high12 Ų1243.1 Ų43.17%0.07426%0.264CS..EExtended strand (participates in β ladder)trans-136.4126.6177.1-53.60000109.8A31 R32 H53 I54A31-T42 WeakPolarHBondContact CA-O 3.17Å; R32-T42 PolarHBondContact N-O 3.21Å; R32-T42 PolarHBondContact O-N 3Å; T42-H53 HydrophobicContact CG2-CB 3.77Å; T42-I54 WeakPolarHBondContact CA-O 3.44Å
43L96.2Very high91.6Very high0 Ų045.6 Ų45.60%028%0.276CS..EExtended strand (participates in β ladder)trans-91.9116.7168.6179.163.1000108.3F29 V45 I54 I56 L65 L77 L88 L98F29-L43 HydrophobicContact CB-CD1 4.46Å; F29-L43 HydrophobicContact CD2-CD1 3.87Å; L43-V45 HydrophobicContact CD1-CG2 4.43Å; L43-V45 HydrophobicContact CD2-CG2 4.36Å; L43-V45 HydrophobicContact CG-CG2 3.89Å; L43-I54 HydrophobicContact CB-CB 4.36Å; L43-I54 HydrophobicContact CD2-CD1 4.12Å; L43-I54 HydrophobicContact CG-CD1 4.41Å; L43-I54 PolarHBondContact N-O 3.32Å; L43-I54 PolarHBondContact O-N 2.99Å; L43-I56 HydrophobicContact CB-CD1 3.92Å; L43-L65 HydrophobicContact CD2-CD1 4.42Å; L43-L77 HydrophobicContact CD2-CD2 4.47Å; L43-L88 HydrophobicContact CD2-CD2 4.24Å; L43-L98 HydrophobicContact CD2-CD1 4.08Å; L43-L98 HydrophobicContact CD2-CD2 4.16Å
44S96.6Very high91.7Very high0 Ų046 Ų460%028%0.277CS..EExtended strand (participates in β ladder)trans-105.1124.7179.7-49.20000108.6F29 L30 R32 T52 H53F29-S44 CarbonylContact C-O 3.51Å; F29-S44 VanDerWaalsContact CA-O 3.23Å; F29-S44 WeakPolarHBondContact CA-O 3.4Å; L30-S44 PolarHBondContact N-O 2.92Å; L30-S44 PolarHBondContact O-N 3.39Å; R32-S44 PolarHBondContact NE-OG 3.23Å; S44-T52 WeakPolarHBondContact CA-O 3.34Å; S44-H53 WeakPolarHBondContact CB-ND1 3.23Å; S44-H53 PolarHBondContact OG-CE1 3.37Å; S44-H53 PolarHBondContact OG-ND1 3.05Å
45V96.3Very high91.9Very high1 Ų149.6 Ų49.61%0.00629%0.293CS..EExtended strand (participates in β ladder)trans-131.2130.5-172.9-169.10000109.8F29 L43 V51 T52 I54 I96 L98F29-V45 HydrophobicContact CB-CB 4.41Å; F29-V45 HydrophobicContact CB-CG1 4.25Å; F29-V45 HydrophobicContact CB-CG2 4.04Å; L43-V45 HydrophobicContact CD1-CG2 4.43Å; L43-V45 HydrophobicContact CD2-CG2 4.36Å; L43-V45 HydrophobicContact CG-CG2 3.89Å; V45-V51 CarbonylContact O-C 3.6Å; V45-V51 WeakPolarHBondContact O-CA 3.41Å; V45-T52 PolarHBondContact N-O 2.89Å; V45-T52 PolarHBondContact O-N 2.87Å; V45-I54 HydrophobicContact CG2-CD1 4.15Å; V45-I96 HydrophobicContact CB-CG2 3.91Å; V45-I96 HydrophobicContact CG1-CG2 3.69Å; V45-I96 HydrophobicContact CG2-CG2 3.97Å; V45-L98 HydrophobicContact CB-CD2 4.47Å; V45-L98 HydrophobicContact CG1-CD2 4.03Å; V45-L98 HydrophobicContact CG2-CD2 3.55Å
46R96.4Very high92.3Very high45 Ų4543.4 Ų43.417%0.1727%0.266CS..EExtended strand (participates in β ladder)trans-84.6128.3172.2-179.8172.6166161.26110.5L20 L21 G24 V25 D26 G27 S28 A50 V51L20-R46 HydrophobicContact CB-CB 4.31Å; L20-R46 HydrophobicContact CD2-CB 4.38Å; L20-R46 WeakPolarHBondContact O-CD 3.46Å; L20-R46 PolarHBondContact O-NH1 2.84Å; L21-R46 PolarHBondContact O-NH1 3.1Å; G24-R46 PolarHBondContact O-NH1 2.86Å; V25-R46 WeakPolarHBondContact O-CD 3.38Å; D26-R46 WeakPolarHBondContact OD1-CG 3.4Å; D26-R46 IonicContact OD1-NE 3.11Å; D26-R46 PolarHBondContact OD1-NE 2.83Å; D26-R46 VanDerWaalsContact OD1-NE 3.11Å; G27-R46 PolarHBondContact N-O 3.48Å; S28-R46 PolarHBondContact O-N 2.77Å; R46-A50 CarbonylContact C-O 3.51Å; R46-A50 VanDerWaalsContact CA-O 3.29Å; R46-A50 WeakPolarHBondContact CA-O 3.3Å; R46-V51 HydrophobicContact CB-CG2 4.45Å
47R92.3Very high92.5Very high44 Ų4441.5 Ų41.517%0.16624%0.244CC..EExtended strand (participates in β ladder)trans-149.3141.9174.669.1178.6-166.1111.4-1.1110.4G49 A50 T52 E90 D94R47-G49 PolarHBondContact O-N 2.99Å; R47-G49 VanDerWaalsContact O-N 3.16Å; R47-A50 PolarHBondContact N-O 3.11Å; R47-A50 CarbonylContact O-C 3.55Å; R47-A50 PolarHBondContact O-N 2.86Å; R47-T52 PolarHBondContact NE-OG1 2.72Å; R47-E90 IonicContact CZ-OE1 3.42Å; R47-E90 VanDerWaalsContact CZ-OE1 3.27Å; R47-E90 IonicContact CZ-OE2 2.86Å; R47-E90 IonicContact NE-OE1 2.78Å; R47-E90 PolarHBondContact NE-OE1 3.32Å; R47-E90 VanDerWaalsContact NE-OE1 3.11Å; R47-E90 IonicContact NH2-OE1 3.11Å; R47-E90 PolarHBondContact NH2-OE1 3.03Å; R47-E90 IonicContact NH2-OE2 2.96Å; R47-E90 PolarHBondContact NH2-OE2 2.99Å; R47-D94 IonicContact CZ-OD2 2.71Å; R47-D94 IonicContact NH1-OD2 3.6Å; R47-D94 PolarHBondContact NH1-OD2 2.87Å; R47-D94 VanDerWaalsContact NH1-OD2 3.08Å; R47-D94 IonicContact NH2-OD2 2.77Å; R47-D94 PolarHBondContact NH2-OD2 2.79Å
48N91.5Very high92.6Very high134 Ų13438.7 Ų38.772%0.71723%0.229SC*.THydrogen-bonded Turntrans50.339.5177.4-58.6-19.8000112.8D26 A50D26-N48 VanDerWaalsContact OD2-CA 3.29Å; D26-N48 WeakPolarHBondContact OD2-CA 3.23Å; D26-N48 PolarHBondContact OD2-N 3.34Å; N48-A50 PolarHBondContact O-N 3.36Å
49G90.7Very high92.2Very high42 Ų4236 Ų3643%0.43321%0.211SC..THydrogen-bonded Turntrans69.14.7-176.500000116.3L21 D26 R47L21-G49 WeakPolarHBondContact CD2-O 3.38Å; D26-G49 PolarHBondContact OD1-N 3.49Å; D26-G49 PolarHBondContact OD2-N 3.24Å; R47-G49 PolarHBondContact O-N 2.99Å; R47-G49 VanDerWaalsContact O-N 3.16Å
50A93.9Very high92.2Very high55 Ų5533.6 Ų33.646%0.45519%0.186SC..EExtended strand (participates in β ladder)trans-119.5169.1177.100000111.5R46 R47 N48R46-A50 CarbonylContact C-O 3.51Å; R46-A50 VanDerWaalsContact CA-O 3.29Å; R46-A50 WeakPolarHBondContact CA-O 3.3Å; R47-A50 PolarHBondContact N-O 3.11Å; R47-A50 CarbonylContact O-C 3.55Å; R47-A50 PolarHBondContact O-N 2.86Å; N48-A50 PolarHBondContact O-N 3.36Å
51V95.7Very high91.8Very high26 Ų2633.2 Ų33.216%0.15818%0.184CC..EExtended strand (participates in β ladder)trans-116.1127178.5177.30000110E17 L20 L21 V45 R46E17-V51 HydrophobicContact CG-CB 4.01Å; E17-V51 HydrophobicContact CG-CG1 3.93Å; L20-V51 HydrophobicContact CB-CG2 3.83Å; L20-V51 HydrophobicContact CD1-CG1 3.71Å; L20-V51 HydrophobicContact CD1-CG2 4.16Å; L21-V51 HydrophobicContact CD2-CG2 4.14Å; L21-V51 HydrophobicContact CG-CG2 4.02Å; V45-V51 CarbonylContact O-C 3.6Å; V45-V51 WeakPolarHBondContact O-CA 3.41Å; R46-V51 HydrophobicContact CB-CG2 4.45Å
52T93.7Very high91.6Very high28 Ų2833.3 Ų33.317%0.17218%0.184CC..EExtended strand (participates in β ladder)trans-102139.8171.8-64.90000109.6S44 V45 R47 I54 E90 I96S44-T52 WeakPolarHBondContact CA-O 3.34Å; V45-T52 PolarHBondContact N-O 2.89Å; V45-T52 PolarHBondContact O-N 2.87Å; R47-T52 PolarHBondContact NE-OG1 2.72Å; T52-I54 HydrophobicContact CG2-CG1 4.12Å; T52-E90 WeakPolarHBondContact CG2-OE1 3.45Å; T52-E90 PolarHBondContact OG1-OE1 3.03Å; T52-I96 HydrophobicContact CG2-CD1 4.41Å
53H94.3Very high91.4Very high67 Ų6732.8 Ų32.831%0.3118%0.181SC..EExtended strand (participates in β ladder)trans-110123.3171.8-64-62.6000111.5E17 R32 T42 S44E17-H53 WeakPolarHBondContact CG-NE2 3.36Å; E17-H53 IonicContact OE1-CD2 3.75Å; E17-H53 IonicContact OE1-NE2 2.97Å; E17-H53 PolarHBondContact OE1-NE2 3.45Å; R32-H53 PolarHBondContact NH2-ND1 2.9Å; T42-H53 HydrophobicContact CG2-CB 3.77Å; S44-H53 WeakPolarHBondContact CB-ND1 3.23Å; S44-H53 PolarHBondContact OG-CE1 3.37Å; S44-H53 PolarHBondContact OG-ND1 3.05Å
54I93.3Very high91.2Very high14 Ų1434.8 Ų34.87%0.07219%0.192CC..EExtended strand (participates in β ladder)trans-112.6125.2-179-47.8156.7000108.5T42 L43 V45 T52 L65 L88 I96T42-I54 WeakPolarHBondContact CA-O 3.44Å; L43-I54 HydrophobicContact CB-CB 4.36Å; L43-I54 HydrophobicContact CD2-CD1 4.12Å; L43-I54 HydrophobicContact CG-CD1 4.41Å; L43-I54 PolarHBondContact N-O 3.32Å; L43-I54 PolarHBondContact O-N 2.99Å; V45-I54 HydrophobicContact CG2-CD1 4.15Å; T52-I54 HydrophobicContact CG2-CG1 4.12Å; I54-L65 HydrophobicContact CB-CD1 4.33Å; I54-L65 HydrophobicContact CG2-CD1 3.58Å; I54-L65 HydrophobicContact CG2-CG 4.19Å; I54-L88 HydrophobicContact CD1-CD2 3.89Å; I54-L88 HydrophobicContact CD1-CG 4.41Å; I54-I96 HydrophobicContact CD1-CD1 3.47Å; I54-I96 VanDerWaalsContact CD1-CD1 3.47Å; I54-I96 HydrophobicContact CD1-CG2 4.34Å; I54-I96 HydrophobicContact CG1-CD1 4Å
55K94.2Very high90.9Very high79 Ų7934.8 Ų34.834%0.34319%0.192SC..EExtended strand (participates in β ladder)trans-74.4135.5-179.5-168.9176.4-175.1-170.40110.6D40 Q57 Y66D40-K55 WeakPolarHBondContact OD2-CE 3.38Å; D40-K55 IonicContact OD2-NZ 3.68Å; D40-K55 PolarHBondContact OD2-NZ 3.44Å; K55-Q57 HydrophobicContact CD-CG 4.22Å; K55-Q57 HydrophobicContact CG-CG 4.25Å; K55-Y66 WeakPolarHBondContact O-CB 3.39Å; K55-Y66 PolarHBondContact O-N 3.36Å
56I94Very high90.4Very high1 Ų140.6 Ų40.61%0.00521%0.214CC..EExtended strand (participates in β ladder)trans-117.2119.3169.6-62.4162.4000107.3D40 F41 L43 Y63 D64 L65 L74 L77D40-I56 WeakPolarHBondContact CB-O 3.38Å; F41-I56 HydrophobicContact CB-CB 4.03Å; F41-I56 HydrophobicContact CB-CD1 4.49Å; F41-I56 HydrophobicContact CB-CG2 4.44Å; F41-I56 PolarHBondContact N-O 2.91Å; F41-I56 PolarHBondContact O-N 3.18Å; L43-I56 HydrophobicContact CB-CD1 3.92Å; I56-Y63 HydrophobicContact CG2-CD1 4.02Å; I56-D64 CarbonylContact C-O 3.56Å; I56-D64 WeakPolarHBondContact CA-O 3.41Å; I56-L65 HydrophobicContact CD1-CD1 4.07Å; I56-L65 HydrophobicContact CG1-CD1 3.36Å; I56-L74 HydrophobicContact CD1-CD2 3.92Å; I56-L74 HydrophobicContact CG2-CD2 4.05Å; I56-L77 HydrophobicContact CD1-CD1 4.1Å; I56-L77 HydrophobicContact CG1-CD1 4.3Å; I56-L77 HydrophobicContact CG2-CD1 4.41Å
57Q92.3Very high89.4Confident73 Ų7341.2 Ų41.234%0.34124%0.235SC..EExtended strand (participates in β ladder)trans-97.3139.7177.8-55.7-162.2-80.600110.5D40 K55 D64D40-Q57 WeakPolarHBondContact OD1-CA 3.38Å; K55-Q57 HydrophobicContact CD-CG 4.22Å; K55-Q57 HydrophobicContact CG-CG 4.25Å; Q57-D64 HydrophobicContact CB-CB 4.45Å; Q57-D64 PolarHBondContact N-O 3.43Å; Q57-D64 PolarHBondContact O-N 3.21Å
58N87.4Confident89Confident9 Ų940.6 Ų40.65%0.04824%0.242CC..EExtended strand (participates in β ladder)trans-136.8106.7169.2-175.2-8.8000109.8D40 F41 G60 Y62 Y63 Q510 T511D40-N58 PolarHBondContact OD1-N 3.5Å; F41-N58 HydrophobicContact CE2-CB 4.44Å; N58-G60 PolarHBondContact OD1-N 2.84Å; N58-Y62 PolarHBondContact OD1-O 3.01Å; N58-Y63 HydrophobicContact CB-CD1 3.99Å; N58-Y63 HydrophobicContact CB-CE1 4.11Å; N58-Y63 VanDerWaalsContact ND2-CE1 3.29Å; N58-Y63 WeakPolarHBondContact ND2-CE1 2.96Å; N58-Y63 WeakPolarHBondContact ND2-CE2 3.28Å; N58-Y63 PolarHBondContact ND2-OH 2.93Å; N58-Q510 PolarHBondContact ND2-O 2.94Å; N58-T511 HydrophobicContact CB-CG2 4.46Å; N58-T511 WeakPolarHBondContact OD1-CG2 3.42Å
59T77.4Confident89Confident47 Ų4737.2 Ų37.229%0.28822%0.221SC..SBendtrans-96.74.6-178.362.70000113.5H430 G431T59-H430 WeakPolarHBondContact CB-ND1 3.44Å; T59-H430 WeakPolarHBondContact CG2-ND1 3.49Å; T59-G431 PolarHBondContact O-N 3.1Å
60G80.3Confident89.2Confident3 Ų338.2 Ų38.23%0.03121%0.214CC..SBendtrans113.3-8.9-179.200000115.1N58 G468 Q510 Q514N58-G60 PolarHBondContact OD1-N 2.84Å; G60-G468 VanDerWaalsContact O-CA 3.26Å; G60-G468 WeakPolarHBondContact O-CA 3.49Å; G60-Q510 WeakPolarHBondContact O-CB 3.28Å; G60-Q514 PolarHBondContact O-NE2 3.11Å
61D81.5Confident89.2Confident3 Ų335.7 Ų35.72%0.01619%0.193CC..SBendtrans-101.1-39.3-179.8-73.7-26.2000113.2K366 I467D61-K366 IonicContact OD2-NZ 3.17Å; D61-K366 PolarHBondContact OD2-NZ 2.94Å; D61-I467 WeakPolarHBondContact O-CD1 3.39Å; D61-I467 VanDerWaalsContact O-CG1 3.31Å; D61-I467 WeakPolarHBondContact O-CG1 3.29Å
62Y90.2Very high89Confident16 Ų1634.5 Ų34.56%0.06319%0.186CC..  trans-171.8168.5-174.445.9-103.7000110.4N58 D64 K70 F71 Y279 I282 A465 Q510N58-Y62 PolarHBondContact OD1-O 3.01Å; Y62-D64 HydrophobicContact CD2-CB 4.12Å; Y62-D64 HydrophobicContact CE2-CB 3.98Å; Y62-K70 HydrophobicContact CD2-CB 3.86Å; Y62-K70 HydrophobicContact CD2-CD 3.82Å; Y62-K70 HydrophobicContact CD2-CG 3.64Å; Y62-K70 HydrophobicContact CE1-CD 4.21Å; Y62-K70 HydrophobicContact CE2-CB 4.32Å; Y62-K70 HydrophobicContact CE2-CD 3.41Å; Y62-K70 VanDerWaalsContact CE2-CD 3.41Å; Y62-K70 HydrophobicContact CE2-CG 3.63Å; Y62-K70 HydrophobicContact CG-CB 4.19Å; Y62-K70 HydrophobicContact CG-CD 4.39Å; Y62-K70 HydrophobicContact CG-CG 4.38Å; Y62-F71 WeakPolarHBondContact CB-O 3.43Å; Y62-Y279 HydrophobicContact CD1-CD2 4.46Å; Y62-Y279 HydrophobicContact CD1-CE1 4.12Å; Y62-Y279 HydrophobicContact CD1-CE2 4.06Å; Y62-Y279 AromaticContact CD1-CZ 3.87Å; Y62-Y279 HydrophobicContact CE1-CD1 4.37Å; Y62-Y279 AromaticContact CE1-CE1 3.58Å; Y62-Y279 HydrophobicContact CE1-CE1 3.58Å; Y62-Y279 HydrophobicContact CE1-CE2 4.01Å; Y62-Y279 AromaticContact CE1-CZ 3.37Å; Y62-Y279 WeakPolarHBondContact CE1-OH 3.3Å; Y62-I282 HydrophobicContact CD1-CD1 4.34Å; Y62-I282 HydrophobicContact CG-CD1 4.25Å; Y62-A465 HydrophobicContact CD1-CB 4.36Å; Y62-Q510 VanDerWaalsContact CA-OE1 3.22Å
63Y90.9Very high88.8Confident1 Ų133.6 Ų33.60%0.00418%0.18CC..EExtended strand (participates in β ladder)trans-87.8116.6169-65.3-94.2000110.2F41 I56 N58 K70 F71 A72 L74 Q255 Q510F41-Y63 HydrophobicContact CD2-CD1 4.26Å; F41-Y63 AromaticContact CD2-CE1 3.93Å; F41-Y63 HydrophobicContact CD2-CE1 3.93Å; F41-Y63 HydrophobicContact CE2-CD1 4.35Å; F41-Y63 AromaticContact CE2-CE1 3.61Å; F41-Y63 HydrophobicContact CE2-CE1 3.61Å; F41-Y63 HydrophobicContact CZ-CE1 4.27Å; I56-Y63 HydrophobicContact CG2-CD1 4.02Å; N58-Y63 HydrophobicContact CB-CD1 3.99Å; N58-Y63 HydrophobicContact CB-CE1 4.11Å; N58-Y63 VanDerWaalsContact ND2-CE1 3.29Å; N58-Y63 WeakPolarHBondContact ND2-CE1 2.96Å; N58-Y63 WeakPolarHBondContact ND2-CE2 3.28Å; N58-Y63 PolarHBondContact ND2-OH 2.93Å; Y63-K70 CarbonylContact O-C 3.58Å; Y63-K70 VanDerWaalsContact O-CA 3.3Å; Y63-K70 WeakPolarHBondContact O-CA 3.44Å; Y63-F71 PolarHBondContact N-O 2.83Å; Y63-F71 PolarHBondContact O-N 3.41Å; Y63-A72 WeakPolarHBondContact CE2-O 3.39Å; Y63-L74 HydrophobicContact CD1-CD2 3.5Å; Y63-L74 VanDerWaalsContact CD1-CD2 3.5Å; Y63-L74 HydrophobicContact CD1-CG 3.72Å; Y63-L74 HydrophobicContact CE1-CD1 4.06Å; Y63-L74 HydrophobicContact CE1-CD2 3.87Å; Y63-L74 HydrophobicContact CE1-CG 3.57Å; Y63-L74 HydrophobicContact CG-CD2 4.17Å; Y63-L74 HydrophobicContact CG-CG 4.41Å; Y63-Q255 PolarHBondContact OH-NE2 2.91Å; Y63-Q510 PolarHBondContact OH-O 2.88Å
64D92.5Very high88.6Confident42 Ų4230.5 Ų30.523%0.22517%0.166CC..EExtended strand (participates in β ladder)trans-105.1107.3-178.6-159.9-14.5000109.8I56 Q57 Y62 K70I56-D64 CarbonylContact C-O 3.56Å; I56-D64 WeakPolarHBondContact CA-O 3.41Å; Q57-D64 HydrophobicContact CB-CB 4.45Å; Q57-D64 PolarHBondContact N-O 3.43Å; Q57-D64 PolarHBondContact O-N 3.21Å; Y62-D64 HydrophobicContact CD2-CB 4.12Å; Y62-D64 HydrophobicContact CE2-CB 3.98Å; D64-K70 HydrophobicContact CB-CG 4.35Å; D64-K70 WeakPolarHBondContact OD2-CE 3.34Å
65L90.4Very high88.3Confident0 Ų030 Ų300%016%0.164CC..EExtended strand (participates in β ladder)trans-81.2123.7177.1-174.866.2000109.5L43 I54 I56 G67 G68 E69 L77 Y81 L88L43-L65 HydrophobicContact CD2-CD1 4.42Å; I54-L65 HydrophobicContact CB-CD1 4.33Å; I54-L65 HydrophobicContact CG2-CD1 3.58Å; I54-L65 HydrophobicContact CG2-CG 4.19Å; I56-L65 HydrophobicContact CD1-CD1 4.07Å; I56-L65 HydrophobicContact CG1-CD1 3.36Å; L65-G67 PolarHBondContact O-N 3Å; L65-G67 VanDerWaalsContact O-N 3.17Å; L65-G68 WeakPolarHBondContact O-CA 3.38Å; L65-G68 PolarHBondContact O-N 3.18Å; L65-E69 PolarHBondContact N-O 3.49Å; L65-L77 HydrophobicContact CB-CD1 4.07Å; L65-L77 HydrophobicContact CD1-CD1 4.45Å; L65-L77 HydrophobicContact CD2-CD2 4.37Å; L65-Y81 HydrophobicContact CD2-CD2 3.9Å; L65-Y81 HydrophobicContact CD2-CE2 3.24Å; L65-L88 HydrophobicContact CD2-CD1 3.41Å; L65-L88 VanDerWaalsContact CD2-CD1 3.41Å; L65-L88 HydrophobicContact CG-CD1 4.26Å
66Y85.3Confident88.1Confident124 Ų12426.5 Ų26.549%0.48615%0.149SC..THydrogen-bonded Turntrans-61.9121.3179.9-171.2-93.6000111.4K55 G68 K91K55-Y66 WeakPolarHBondContact O-CB 3.39Å; K55-Y66 PolarHBondContact O-N 3.36Å; Y66-G68 VanDerWaalsContact C-N 3.27Å; Y66-K91 VanDerWaalsContact CE1-CE 3.44Å; Y66-K91 HydrophobicContact CE1-CG 4.41Å; Y66-K91 WeakPolarHBondContact OH-CE 3.31Å; Y66-K91 PolarHBondContact OH-NZ 2.77Å; Y66-K91 VanDerWaalsContact OH-NZ 3.13Å
67G76.1Confident88Confident58 Ų5826.5 Ų26.560%0.59815%0.149SC*.THydrogen-bonded Turntrans78.18.4-174.600000114.4L65L65-G67 PolarHBondContact O-N 3Å; L65-G67 VanDerWaalsContact O-N 3.17Å
68G84.6Confident87.9Confident30 Ų3023.1 Ų23.131%0.30913%0.133SC..SBendtrans-126.8-148.5-179.300000113.5L65 Y66 Y81L65-G68 WeakPolarHBondContact O-CA 3.38Å; L65-G68 PolarHBondContact O-N 3.18Å; Y66-G68 VanDerWaalsContact C-N 3.27Å; G68-Y81 VanDerWaalsContact CA-OH 3.26Å; G68-Y81 WeakPolarHBondContact CA-OH 3.43Å
69E90.9Very high88Confident63 Ų6324.4 Ų24.429%0.29414%0.139SC..  trans-107.5175.6-177-63.3-87-163.600111.1L65 F71 Y81 K280 N281L65-E69 PolarHBondContact N-O 3.49Å; E69-F71 HydrophobicContact CB-CE2 3.73Å; E69-F71 HydrophobicContact CB-CZ 3.84Å; E69-F71 WeakPolarHBondContact O-CD2 3.36Å; E69-F71 WeakPolarHBondContact O-CE2 3.41Å; E69-Y81 PolarHBondContact N-OH 2.77Å; E69-K280 IonicContact OE1-NZ 3.08Å; E69-K280 PolarHBondContact OE1-NZ 2.87Å; E69-N281 VanDerWaalsContact CB-ND2 3.28Å; E69-N281 WeakPolarHBondContact CB-ND2 3.19Å
70K93.9Very high88.7Confident64 Ų6423.5 Ų23.528%0.27813%0.13SC..EExtended strand (participates in β ladder)trans-104.8139.6178.8-65.2162-176.9133.70111.4Y62 Y63 D64 Y279 N281Y62-K70 HydrophobicContact CD2-CB 3.86Å; Y62-K70 HydrophobicContact CD2-CD 3.82Å; Y62-K70 HydrophobicContact CD2-CG 3.64Å; Y62-K70 HydrophobicContact CE1-CD 4.21Å; Y62-K70 HydrophobicContact CE2-CB 4.32Å; Y62-K70 HydrophobicContact CE2-CD 3.41Å; Y62-K70 VanDerWaalsContact CE2-CD 3.41Å; Y62-K70 HydrophobicContact CE2-CG 3.63Å; Y62-K70 HydrophobicContact CG-CB 4.19Å; Y62-K70 HydrophobicContact CG-CD 4.39Å; Y62-K70 HydrophobicContact CG-CG 4.38Å; Y63-K70 CarbonylContact O-C 3.58Å; Y63-K70 VanDerWaalsContact O-CA 3.3Å; Y63-K70 WeakPolarHBondContact O-CA 3.44Å; D64-K70 HydrophobicContact CB-CG 4.35Å; D64-K70 WeakPolarHBondContact OD2-CE 3.34Å; K70-Y279 HydrophobicContact CB-CD1 4.42Å; K70-Y279 HydrophobicContact CD-CD1 3.58Å; K70-Y279 HydrophobicContact CD-CE1 3.72Å; K70-N281 WeakPolarHBondContact O-CB 3.43Å
71F93.7Very high89.3Confident2 Ų223.7 Ų23.71%0.00913%0.13CC..EExtended strand (participates in β ladder)trans-134.2156.3-173.6-61.5-88.7000112.6Y62 Y63 E69 L77 Y80 Y81 N281Y62-F71 WeakPolarHBondContact CB-O 3.43Å; Y63-F71 PolarHBondContact N-O 2.83Å; Y63-F71 PolarHBondContact O-N 3.41Å; E69-F71 HydrophobicContact CB-CE2 3.73Å; E69-F71 HydrophobicContact CB-CZ 3.84Å; E69-F71 WeakPolarHBondContact O-CD2 3.36Å; E69-F71 WeakPolarHBondContact O-CE2 3.41Å; F71-L77 HydrophobicContact CB-CB 3.97Å; F71-L77 HydrophobicContact CD1-CB 4.23Å; F71-L77 HydrophobicContact CD2-CB 3.69Å; F71-L77 HydrophobicContact CD2-CD1 3.87Å; F71-L77 HydrophobicContact CD2-CG 3.68Å; F71-L77 HydrophobicContact CE2-CB 4.24Å; F71-L77 HydrophobicContact CE2-CD1 4.4Å; F71-L77 HydrophobicContact CE2-CG 3.93Å; F71-L77 HydrophobicContact CG-CB 3.68Å; F71-L77 HydrophobicContact CG-CG 4.22Å; F71-Y80 VanDerWaalsContact CE1-CB 3.45Å; F71-Y80 AromaticContact CE1-CD1 3.78Å; F71-Y80 HydrophobicContact CE1-CD1 3.78Å; F71-Y80 HydrophobicContact CE1-CD2 4.13Å; F71-Y80 AromaticContact CE1-CG 3.52Å; F71-Y80 HydrophobicContact CE1-CG 3.52Å; F71-Y80 AromaticContact CZ-CD1 3.51Å; F71-Y80 HydrophobicContact CZ-CD1 3.51Å; F71-Y80 HydrophobicContact CZ-CE1 4.14Å; F71-Y80 AromaticContact CZ-CG 3.78Å; F71-Y80 HydrophobicContact CZ-CG 3.78Å; F71-Y81 HydrophobicContact CE2-CD2 4.42Å; F71-Y81 AromaticContact CE2-CE2 3.54Å; F71-Y81 HydrophobicContact CE2-CE2 3.54Å; F71-Y81 HydrophobicContact CZ-CD2 4.27Å; F71-Y81 AromaticContact CZ-CE2 3.62Å; F71-Y81 HydrophobicContact CZ-CE2 3.62Å; F71-N281 HydrophobicContact CD1-CB 3.59Å; F71-N281 HydrophobicContact CE1-CB 3.59Å; F71-N281 WeakPolarHBondContact CE1-ND2 3.21Å; F71-N281 HydrophobicContact CG-CB 4.44Å; F71-N281 HydrophobicContact CZ-CB 4.44Å; F71-N281 VanDerWaalsContact CZ-ND2 3.26Å; F71-N281 WeakPolarHBondContact CZ-ND2 3.33Å
72A91.6Very high89.7Confident1 Ų125.7 Ų25.71%0.00814%0.14CC..SBendtrans-78.7-30.3177.500000112.4Y63 E76 I282 I467 Q510Y63-A72 WeakPolarHBondContact CE2-O 3.39Å; A72-E76 WeakPolarHBondContact CB-OE2 3.41Å; A72-I282 HydrophobicContact CB-CG1 4.38Å; A72-I282 HydrophobicContact CB-CG2 4.24Å; A72-I467 HydrophobicContact CB-CD1 3.73Å; A72-Q510 PolarHBondContact O-NE2 2.82Å; A72-Q510 PolarHBondContact O-OE1 2.87Å
73T90.3Very high89.7Confident9 Ų930.6 Ų30.66%0.05516%0.163CC..SBendtrans-141.7161.3178.967.60000111.6A75 E76 L77 E258T73-A75 VanDerWaalsContact C-N 3.32Å; T73-E76 PolarHBondContact O-N 3.33Å; T73-E76 WeakPolarHBondContact OG1-CB 3.48Å; T73-E76 VanDerWaalsContact OG1-CG 3.24Å; T73-E76 WeakPolarHBondContact OG1-CG 3.39Å; T73-E76 PolarHBondContact OG1-N 3.03Å; T73-E76 VanDerWaalsContact OG1-N 3.09Å; T73-L77 PolarHBondContact O-N 2.72Å; T73-L77 VanDerWaalsContact O-N 3.12Å; T73-E258 WeakPolarHBondContact CB-OE2 3.32Å
74L89.1Confident89.7Confident1 Ų134 Ų341%0.00518%0.179CC..Hα-helixtrans-66-36.5173.5-71.2177.5000111.3W6 F7 F41 I56 Y63 E76 L77 V78W6-L74 HydrophobicContact CH2-CB 3.75Å; W6-L74 HydrophobicContact CZ3-CB 4.25Å; F7-L74 HydrophobicContact CD2-CD1 4.19Å; F7-L74 HydrophobicContact CE2-CD1 3.87Å; F41-L74 HydrophobicContact CD1-CD1 3.9Å; F41-L74 HydrophobicContact CD2-CD1 4.47Å; F41-L74 HydrophobicContact CE1-CD1 4.12Å; F41-L74 HydrophobicContact CG-CD1 4.07Å; I56-L74 HydrophobicContact CD1-CD2 3.92Å; I56-L74 HydrophobicContact CG2-CD2 4.05Å; Y63-L74 HydrophobicContact CD1-CD2 3.5Å; Y63-L74 VanDerWaalsContact CD1-CD2 3.5Å; Y63-L74 HydrophobicContact CD1-CG 3.72Å; Y63-L74 HydrophobicContact CE1-CD1 4.06Å; Y63-L74 HydrophobicContact CE1-CD2 3.87Å; Y63-L74 HydrophobicContact CE1-CG 3.57Å; Y63-L74 HydrophobicContact CG-CD2 4.17Å; Y63-L74 HydrophobicContact CG-CG 4.41Å; L74-E76 PolarHBondContact O-N 3.41Å; L74-L77 HydrophobicContact CD2-CD1 4.46Å; L74-L77 WeakPolarHBondContact O-CB 3.24Å; L74-L77 PolarHBondContact O-N 3.27Å; L74-V78 WeakPolarHBondContact O-CG2 3.41Å; L74-V78 PolarHBondContact O-N 3.42Å
75A88.8Confident89.4Confident4 Ų437.3 Ų37.33%0.03319%0.193CC..Hα-helixtrans-61.1-41.5174.600000113.1W6 T73 V78 Q79 E258 L262W6-A75 HydrophobicContact CZ2-CB 4.25Å; T73-A75 VanDerWaalsContact C-N 3.32Å; A75-V78 PolarHBondContact O-N 3.05Å; A75-Q79 VanDerWaalsContact O-CB 3.22Å; A75-Q79 WeakPolarHBondContact O-CB 3.21Å; A75-Q79 PolarHBondContact O-N 3.05Å; A75-E258 HydrophobicContact CB-CG 3.63Å; A75-E258 WeakPolarHBondContact CB-OE1 3.13Å; A75-E258 PolarHBondContact N-OE1 3.47Å; A75-L262 HydrophobicContact CB-CD2 4.29Å
76E88.3Confident89Confident6 Ų638.7 Ų38.73%0.02821%0.207CC..Hα-helixtrans-66.6-39.2175.2-72.6178.4178.700112.3A72 T73 L74 Y80 L262 R265 S506A72-E76 WeakPolarHBondContact CB-OE2 3.41Å; T73-E76 PolarHBondContact O-N 3.33Å; T73-E76 WeakPolarHBondContact OG1-CB 3.48Å; T73-E76 VanDerWaalsContact OG1-CG 3.24Å; T73-E76 WeakPolarHBondContact OG1-CG 3.39Å; T73-E76 PolarHBondContact OG1-N 3.03Å; T73-E76 VanDerWaalsContact OG1-N 3.09Å; L74-E76 PolarHBondContact O-N 3.41Å; E76-Y80 VanDerWaalsContact O-CB 3.25Å; E76-Y80 WeakPolarHBondContact O-CB 3.46Å; E76-Y80 PolarHBondContact O-N 3.4Å; E76-L262 HydrophobicContact CG-CD2 4.08Å; E76-R265 VanDerWaalsContact CG-NH1 3.27Å; E76-R265 IonicContact OE1-CZ 2.77Å; E76-R265 IonicContact OE1-NE 3.89Å; E76-R265 IonicContact OE1-NH1 3.97Å; E76-R265 PolarHBondContact OE1-NH1 2.81Å; E76-R265 IonicContact OE2-NH1 2.78Å; E76-R265 PolarHBondContact OE2-NH1 3.03Å; E76-S506 VanDerWaalsContact CD-OG 3.3Å; E76-S506 WeakPolarHBondContact OE1-CB 3.38Å; E76-S506 PolarHBondContact OE1-OG 3.38Å
77L92.7Very high89.1Confident1 Ų136.7 Ų36.71%0.00520%0.203CC..Hα-helixtrans-58.5-51.5174.1-179.7162.1000110.8L43 I56 L65 F71 T73 L74 Y80 Y81L43-L77 HydrophobicContact CD2-CD2 4.47Å; I56-L77 HydrophobicContact CD1-CD1 4.1Å; I56-L77 HydrophobicContact CG1-CD1 4.3Å; I56-L77 HydrophobicContact CG2-CD1 4.41Å; L65-L77 HydrophobicContact CB-CD1 4.07Å; L65-L77 HydrophobicContact CD1-CD1 4.45Å; L65-L77 HydrophobicContact CD2-CD2 4.37Å; F71-L77 HydrophobicContact CB-CB 3.97Å; F71-L77 HydrophobicContact CD1-CB 4.23Å; F71-L77 HydrophobicContact CD2-CB 3.69Å; F71-L77 HydrophobicContact CD2-CD1 3.87Å; F71-L77 HydrophobicContact CD2-CG 3.68Å; F71-L77 HydrophobicContact CE2-CB 4.24Å; F71-L77 HydrophobicContact CE2-CD1 4.4Å; F71-L77 HydrophobicContact CE2-CG 3.93Å; F71-L77 HydrophobicContact CG-CB 3.68Å; F71-L77 HydrophobicContact CG-CG 4.22Å; T73-L77 PolarHBondContact O-N 2.72Å; T73-L77 VanDerWaalsContact O-N 3.12Å; L74-L77 HydrophobicContact CD2-CD1 4.46Å; L74-L77 WeakPolarHBondContact O-CB 3.24Å; L74-L77 PolarHBondContact O-N 3.27Å; L77-Y80 PolarHBondContact O-N 2.85Å; L77-Y81 HydrophobicContact CD2-CD2 4.06Å; L77-Y81 HydrophobicContact CD2-CE2 4.45Å; L77-Y81 HydrophobicContact CG-CD2 4.24Å; L77-Y81 HydrophobicContact CG-CE2 4.27Å; L77-Y81 VanDerWaalsContact O-CD2 3.29Å; L77-Y81 WeakPolarHBondContact O-CD2 3.36Å; L77-Y81 PolarHBondContact O-N 3.38Å
78V90.7Very high89.7Confident2 Ų234 Ų341%0.01218%0.175CC..Hα-helixtrans-63.7-47-179.9168.90000110.7M1 W6 F29 L74 A75 Y80 Y81 M82M1-V78 HydrophobicContact CE-CG1 3.79Å; M1-V78 HydrophobicContact SD-CG1 4.35Å; W6-V78 HydrophobicContact CD2-CG1 4.37Å; W6-V78 HydrophobicContact CD2-CG2 4.14Å; W6-V78 HydrophobicContact CE3-CG2 3.9Å; W6-V78 HydrophobicContact CH2-CB 4.33Å; W6-V78 HydrophobicContact CH2-CG2 3.71Å; W6-V78 HydrophobicContact CZ2-CB 4.1Å; W6-V78 HydrophobicContact CZ2-CG1 4.46Å; W6-V78 HydrophobicContact CZ2-CG2 3.93Å; W6-V78 HydrophobicContact CZ3-CG2 3.68Å; F29-V78 HydrophobicContact CE2-CG1 3.57Å; F29-V78 HydrophobicContact CE2-CG2 4.19Å; F29-V78 HydrophobicContact CZ-CG1 3.57Å; L74-V78 WeakPolarHBondContact O-CG2 3.41Å; L74-V78 PolarHBondContact O-N 3.42Å; A75-V78 PolarHBondContact O-N 3.05Å; V78-Y80 VanDerWaalsContact C-N 3.31Å; V78-Y80 PolarHBondContact O-N 2.66Å; V78-Y81 PolarHBondContact O-N 3.36Å; V78-M82 HydrophobicContact CG1-CG 4.33Å; V78-M82 HydrophobicContact CG1-SD 3.81Å; V78-M82 WeakPolarHBondContact O-CB 3.42Å; V78-M82 VanDerWaalsContact O-CG 3.29Å; V78-M82 WeakPolarHBondContact O-CG 3.49Å; V78-M82 PolarHBondContact O-N 2.83Å
79Q88.2Confident89.8Confident36 Ų3637.6 Ų37.617%0.16818%0.182CC..Hα-helixtrans-57-46.2177.8-177.8177.411.700111.2A75 Y81 M82 E83A75-Q79 VanDerWaalsContact O-CB 3.22Å; A75-Q79 WeakPolarHBondContact O-CB 3.21Å; A75-Q79 PolarHBondContact O-N 3.05Å; Q79-Y81 PolarHBondContact O-N 2.9Å; Q79-M82 PolarHBondContact O-N 2.81Å; Q79-E83 HydrophobicContact CG-CG 4.47Å; Q79-E83 WeakPolarHBondContact CG-OE1 3.49Å; Q79-E83 PolarHBondContact NE2-OE1 3.47Å; Q79-E83 WeakPolarHBondContact O-CB 2.93Å; Q79-E83 WeakPolarHBondContact O-CG 3.39Å; Q79-E83 PolarHBondContact O-N 3.39Å
80Y92.1Very high89.2Confident28 Ų2837.1 Ų37.111%0.1118%0.179CC..Hα-helixtrans-57.7-52.9-179.6-177.9-97.6000112.3F71 E76 L77 V78 M82 E83 H84 Q87 K280F71-Y80 VanDerWaalsContact CE1-CB 3.45Å; F71-Y80 AromaticContact CE1-CD1 3.78Å; F71-Y80 HydrophobicContact CE1-CD1 3.78Å; F71-Y80 HydrophobicContact CE1-CD2 4.13Å; F71-Y80 AromaticContact CE1-CG 3.52Å; F71-Y80 HydrophobicContact CE1-CG 3.52Å; F71-Y80 AromaticContact CZ-CD1 3.51Å; F71-Y80 HydrophobicContact CZ-CD1 3.51Å; F71-Y80 HydrophobicContact CZ-CE1 4.14Å; F71-Y80 AromaticContact CZ-CG 3.78Å; F71-Y80 HydrophobicContact CZ-CG 3.78Å; E76-Y80 VanDerWaalsContact O-CB 3.25Å; E76-Y80 WeakPolarHBondContact O-CB 3.46Å; E76-Y80 PolarHBondContact O-N 3.4Å; L77-Y80 PolarHBondContact O-N 2.85Å; V78-Y80 VanDerWaalsContact C-N 3.31Å; V78-Y80 PolarHBondContact O-N 2.66Å; Y80-M82 VanDerWaalsContact C-N 3.3Å; Y80-M82 PolarHBondContact O-N 3.13Å; Y80-E83 PolarHBondContact O-N 3.25Å; Y80-H84 AromaticContact CD2-CE1 3.88Å; Y80-H84 AromaticContact CD2-ND1 3.7Å; Y80-H84 HydrophobicContact CE1-CB 4.5Å; Y80-H84 AromaticContact CE2-CE1 3.84Å; Y80-H84 AromaticContact CE2-ND1 3.81Å; Y80-H84 WeakPolarHBondContact O-CB 3.44Å; Y80-H84 PolarHBondContact O-N 3.36Å; Y80-H84 PolarHBondContact O-ND1 2.91Å; Y80-Q87 PolarHBondContact OH-OE1 2.85Å; Y80-K280 PolarHBondContact OH-NZ 2.81Å
81Y93.6Very high88.4Confident6 Ų642.5 Ų42.52%0.02420%0.203CC..Hα-helixtrans-75.2-18.9-176.5-73.5-64.2000114L65 G68 E69 F71 L77 V78 Q79 Q87 L88L65-Y81 HydrophobicContact CD2-CD2 3.9Å; L65-Y81 HydrophobicContact CD2-CE2 3.24Å; G68-Y81 VanDerWaalsContact CA-OH 3.26Å; G68-Y81 WeakPolarHBondContact CA-OH 3.43Å; E69-Y81 PolarHBondContact N-OH 2.77Å; F71-Y81 HydrophobicContact CE2-CD2 4.42Å; F71-Y81 AromaticContact CE2-CE2 3.54Å; F71-Y81 HydrophobicContact CE2-CE2 3.54Å; F71-Y81 HydrophobicContact CZ-CD2 4.27Å; F71-Y81 AromaticContact CZ-CE2 3.62Å; F71-Y81 HydrophobicContact CZ-CE2 3.62Å; L77-Y81 HydrophobicContact CD2-CD2 4.06Å; L77-Y81 HydrophobicContact CD2-CE2 4.45Å; L77-Y81 HydrophobicContact CG-CD2 4.24Å; L77-Y81 HydrophobicContact CG-CE2 4.27Å; L77-Y81 VanDerWaalsContact O-CD2 3.29Å; L77-Y81 WeakPolarHBondContact O-CD2 3.36Å; L77-Y81 PolarHBondContact O-N 3.38Å; V78-Y81 PolarHBondContact O-N 3.36Å; Q79-Y81 PolarHBondContact O-N 2.9Å; Y81-Q87 HydrophobicContact CD1-CB 4.42Å; Y81-Q87 HydrophobicContact CE1-CB 4.16Å; Y81-L88 HydrophobicContact CD1-CB 3.62Å; Y81-L88 HydrophobicContact CE1-CB 3.79Å; Y81-L88 HydrophobicContact CE1-CD1 4.26Å; Y81-L88 HydrophobicContact CG-CB 4.26Å
82M90.7Very high87.9Confident46 Ų4647.2 Ų47.223%0.22723%0.228CC..Hα-helixtrans-75.7-32.5168.3-75.4-172.163.900113M1 F29 V78 Q79 Y80 H85 L98M1-M82 HydrophobicContact CE-CE 3.64Å; M1-M82 HydrophobicContact CE-SD 2.96Å; M1-M82 WeakPolarHBondContact CE-SD 3.44Å; F29-M82 HydrophobicContact CE1-CE 4.37Å; F29-M82 HydrophobicContact CE1-CG 4.2Å; F29-M82 HydrophobicContact CE1-SD 3.63Å; F29-M82 HydrophobicContact CZ-CG 4.24Å; F29-M82 HydrophobicContact CZ-SD 3.44Å; F29-M82 WeakPolarHBondContact CZ-SD 3.39Å; V78-M82 HydrophobicContact CG1-CG 4.33Å; V78-M82 HydrophobicContact CG1-SD 3.81Å; V78-M82 WeakPolarHBondContact O-CB 3.42Å; V78-M82 VanDerWaalsContact O-CG 3.29Å; V78-M82 WeakPolarHBondContact O-CG 3.49Å; V78-M82 PolarHBondContact O-N 2.83Å; Q79-M82 PolarHBondContact O-N 2.81Å; Y80-M82 VanDerWaalsContact C-N 3.3Å; Y80-M82 PolarHBondContact O-N 3.13Å; M82-H85 PolarHBondContact O-CE1 2.94Å; M82-L98 HydrophobicContact CG-CB 3.68Å
83E90.6Very high87.4Confident118 Ų11849.2 Ų49.255%0.55125%0.249SC*.Hα-helixtrans-86.4-20.8178.3-69171.1-173.400112.6Q79 Y80Q79-E83 HydrophobicContact CG-CG 4.47Å; Q79-E83 WeakPolarHBondContact CG-OE1 3.49Å; Q79-E83 PolarHBondContact NE2-OE1 3.47Å; Q79-E83 WeakPolarHBondContact O-CB 2.93Å; Q79-E83 WeakPolarHBondContact O-CG 3.39Å; Q79-E83 PolarHBondContact O-N 3.39Å; Y80-E83 PolarHBondContact O-N 3.25Å
84H89.2Confident87.1Confident73 Ų7352 Ų5234%0.33826%0.263SS..SBendtrans-120.273.6-175.8-59.679.7000112.2Y80 Q87Y80-H84 AromaticContact CD2-CE1 3.88Å; Y80-H84 AromaticContact CD2-ND1 3.7Å; Y80-H84 HydrophobicContact CE1-CB 4.5Å; Y80-H84 AromaticContact CE2-CE1 3.84Å; Y80-H84 AromaticContact CE2-ND1 3.81Å; Y80-H84 WeakPolarHBondContact O-CB 3.44Å; Y80-H84 PolarHBondContact O-N 3.36Å; Y80-H84 PolarHBondContact O-ND1 2.91Å; H84-Q87 HydrophobicContact CB-CG 4.22Å
85H86.1Confident87.1Confident112 Ų11254.9 Ų54.952%0.51928%0.281SS..THydrogen-bonded Turntrans-57.1145.1174.3-55.2-48.3000111.7M82M82-H85 PolarHBondContact O-CE1 2.94Å
86G83.2Confident87.2Confident29 Ų2955 Ų5530%0.29928%0.281SS..THydrogen-bonded Turntrans89.6-11.317900000116.3K89G86-K89 WeakPolarHBondContact O-CE 3.26Å
87Q87.2Confident87.3Confident82 Ų8258.1 Ų58.138%0.38330%0.295SS..  trans-91.1-28.5-176-63.6-157.620.200114.8Y80 Y81 H84Y80-Q87 PolarHBondContact OH-OE1 2.85Å; Y81-Q87 HydrophobicContact CD1-CB 4.42Å; Y81-Q87 HydrophobicContact CE1-CB 4.16Å; H84-Q87 HydrophobicContact CB-CG 4.22Å
88L88.6Confident87.4Confident2 Ų258.1 Ų58.11%0.0130%0.295CS..  trans-82.6119.6174.9-175.156.9000109.1L43 I54 L65 Y81 V95 I96 L98L43-L88 HydrophobicContact CD2-CD2 4.24Å; I54-L88 HydrophobicContact CD1-CD2 3.89Å; I54-L88 HydrophobicContact CD1-CG 4.41Å; L65-L88 HydrophobicContact CD2-CD1 3.41Å; L65-L88 VanDerWaalsContact CD2-CD1 3.41Å; L65-L88 HydrophobicContact CG-CD1 4.26Å; Y81-L88 HydrophobicContact CD1-CB 3.62Å; Y81-L88 HydrophobicContact CE1-CB 3.79Å; Y81-L88 HydrophobicContact CE1-CD1 4.26Å; Y81-L88 HydrophobicContact CG-CB 4.26Å; L88-V95 WeakPolarHBondContact O-CA 3.29Å; L88-I96 HydrophobicContact CB-CB 4.42Å; L88-I96 HydrophobicContact CD2-CB 4.03Å; L88-I96 HydrophobicContact CD2-CG2 4.11Å; L88-I96 HydrophobicContact CG-CB 3.96Å; L88-I96 HydrophobicContact CG-CD1 4.3Å; L88-I96 PolarHBondContact O-N 3.07Å; L88-L98 HydrophobicContact CD2-CD2 4.37Å; L88-L98 HydrophobicContact CD2-CG 4.41Å
89K85.9Confident87.4Confident105 Ų10562 Ų6246%0.45731%0.312SS..BIsolated β-bridgetrans-132147.9-175.2-60.9-177-177.4-175.80112.3G86 D94 V95G86-K89 WeakPolarHBondContact O-CE 3.26Å; K89-D94 CarbonylContact C-O 3.51Å; K89-D94 WeakPolarHBondContact CA-O 3.26Å; K89-V95 HydrophobicContact CG-CG2 4.42Å
90E79.1Confident87.5Confident53 Ų5366.3 Ų66.325%0.24833%0.328CS..  trans-77.6172.3167.7-74.7-167.3-17300111.8R47 T52 N92 G93 D94 I96R47-E90 IonicContact CZ-OE1 3.42Å; R47-E90 VanDerWaalsContact CZ-OE1 3.27Å; R47-E90 IonicContact CZ-OE2 2.86Å; R47-E90 IonicContact NE-OE1 2.78Å; R47-E90 PolarHBondContact NE-OE1 3.32Å; R47-E90 VanDerWaalsContact NE-OE1 3.11Å; R47-E90 IonicContact NH2-OE1 3.11Å; R47-E90 PolarHBondContact NH2-OE1 3.03Å; R47-E90 IonicContact NH2-OE2 2.96Å; R47-E90 PolarHBondContact NH2-OE2 2.99Å; T52-E90 WeakPolarHBondContact CG2-OE1 3.45Å; T52-E90 PolarHBondContact OG1-OE1 3.03Å; E90-N92 VanDerWaalsContact CB-OD1 3.23Å; E90-N92 WeakPolarHBondContact CB-OD1 3.26Å; E90-N92 PolarHBondContact O-N 3.05Å; E90-G93 PolarHBondContact O-N 2.83Å; E90-D94 PolarHBondContact N-O 2.8Å; E90-I96 HydrophobicContact CG-CD1 3.58Å; E90-I96 HydrophobicContact CG-CG1 3.96Å
91K77.8Confident87.4Confident177 Ų17767.1 Ų67.177%0.7734%0.336SS*.THydrogen-bonded Turntrans-58.8-29.9175.8-72.9-170.7179.9-175.10113.5Y66Y66-K91 VanDerWaalsContact CE1-CE 3.44Å; Y66-K91 HydrophobicContact CE1-CG 4.41Å; Y66-K91 WeakPolarHBondContact OH-CE 3.31Å; Y66-K91 PolarHBondContact OH-NZ 2.77Å; Y66-K91 VanDerWaalsContact OH-NZ 3.13Å
92N81.5Confident87.1Confident100 Ų10067.8 Ų67.854%0.53534%0.34SS..THydrogen-bonded Turntrans-80.7-4.8178.167.8-6.8000112.9E90 D94E90-N92 VanDerWaalsContact CB-OD1 3.23Å; E90-N92 WeakPolarHBondContact CB-OD1 3.26Å; E90-N92 PolarHBondContact O-N 3.05Å; N92-D94 VanDerWaalsContact ND2-CG 3.31Å; N92-D94 PolarHBondContact ND2-OD2 3.49Å; N92-D94 VanDerWaalsContact OD1-CB 3.32Å; N92-D94 WeakPolarHBondContact OD1-CB 3.25Å; N92-D94 PolarHBondContact OD1-N 3.32Å
93G81.4Confident86.8Confident43 Ų4369.3 Ų69.344%0.44335%0.349SS..SBendtrans93.8-5.1-178.900000115.1E90E90-G93 PolarHBondContact O-N 2.83Å
94D85.4Confident86.3Confident67 Ų6764.6 Ų64.636%0.35833%0.329SS..  trans-62.9137.9178-73.7-11.4000111.3R47 K89 E90 N92R47-D94 IonicContact CZ-OD2 2.71Å; R47-D94 IonicContact NH1-OD2 3.6Å; R47-D94 PolarHBondContact NH1-OD2 2.87Å; R47-D94 VanDerWaalsContact NH1-OD2 3.08Å; R47-D94 IonicContact NH2-OD2 2.77Å; R47-D94 PolarHBondContact NH2-OD2 2.79Å; K89-D94 CarbonylContact C-O 3.51Å; K89-D94 WeakPolarHBondContact CA-O 3.26Å; E90-D94 PolarHBondContact N-O 2.8Å; N92-D94 VanDerWaalsContact ND2-CG 3.31Å; N92-D94 PolarHBondContact ND2-OD2 3.49Å; N92-D94 VanDerWaalsContact OD1-CB 3.32Å; N92-D94 WeakPolarHBondContact OD1-CB 3.25Å; N92-D94 PolarHBondContact OD1-N 3.32Å
95V88.3Confident85.6Confident62 Ų6263.2 Ų63.238%0.37633%0.33SS..BIsolated β-bridgetrans-78.4135175.7175.90000110.4L88 K89 E97L88-V95 WeakPolarHBondContact O-CA 3.29Å; K89-V95 HydrophobicContact CG-CG2 4.42Å; V95-E97 HydrophobicContact CG1-CG 4Å
96I90.1Very high84.9Confident6 Ų660.1 Ų60.13%0.03132%0.317CS..  trans-108.9123.1171.2-49.7176.2000108.2V45 T52 I54 L88 E90V45-I96 HydrophobicContact CB-CG2 3.91Å; V45-I96 HydrophobicContact CG1-CG2 3.69Å; V45-I96 HydrophobicContact CG2-CG2 3.97Å; T52-I96 HydrophobicContact CG2-CD1 4.41Å; I54-I96 HydrophobicContact CD1-CD1 3.47Å; I54-I96 VanDerWaalsContact CD1-CD1 3.47Å; I54-I96 HydrophobicContact CD1-CG2 4.34Å; I54-I96 HydrophobicContact CG1-CD1 4Å; L88-I96 HydrophobicContact CB-CB 4.42Å; L88-I96 HydrophobicContact CD2-CB 4.03Å; L88-I96 HydrophobicContact CD2-CG2 4.11Å; L88-I96 HydrophobicContact CG-CB 3.96Å; L88-I96 HydrophobicContact CG-CD1 4.3Å; L88-I96 PolarHBondContact O-N 3.07Å; E90-I96 HydrophobicContact CG-CD1 3.58Å; E90-I96 HydrophobicContact CG-CG1 3.96Å
97E92Very high84.4Confident73 Ų7359.3 Ų59.334%0.34131%0.307SS..  trans-105.1128.7-179.1-61.5-173.7144.400111.3V95 K99V95-E97 HydrophobicContact CG1-CG 4Å; E97-K99 HydrophobicContact CB-CG 4.36Å; E97-K99 WeakPolarHBondContact OE2-CE 3.45Å; E97-K99 IonicContact OE2-NZ 2.64Å; E97-K99 PolarHBondContact OE2-NZ 2.86Å
98L93.1Very high83.5Confident1 Ų157.4 Ų57.41%0.00530%0.301CS..  trans-94.7107.6169.8-54-171.3000108.5F29 L43 V45 M82 L88F29-L98 HydrophobicContact CB-CD2 3.86Å; F29-L98 HydrophobicContact CD1-CB 3.84Å; F29-L98 HydrophobicContact CD1-CD2 4.2Å; F29-L98 HydrophobicContact CD2-CD2 4.42Å; F29-L98 HydrophobicContact CE1-CB 3.95Å; F29-L98 HydrophobicContact CG-CB 4.34Å; F29-L98 HydrophobicContact CG-CD2 3.9Å; L43-L98 HydrophobicContact CD2-CD1 4.08Å; L43-L98 HydrophobicContact CD2-CD2 4.16Å; V45-L98 HydrophobicContact CB-CD2 4.47Å; V45-L98 HydrophobicContact CG1-CD2 4.03Å; V45-L98 HydrophobicContact CG2-CD2 3.55Å; M82-L98 HydrophobicContact CG-CB 3.68Å; L88-L98 HydrophobicContact CD2-CD2 4.37Å; L88-L98 HydrophobicContact CD2-CG 4.41Å
99K92Very high82.4Confident83 Ų8357.7 Ų57.736%0.36130%0.303SS..  trans-113.5-53.8-178.5-67.5-178176.1163.70112.1G27 E97G27-K99 PolarHBondContact O-N 3.42Å; E97-K99 HydrophobicContact CB-CG 4.36Å; E97-K99 WeakPolarHBondContact OE2-CE 3.45Å; E97-K99 IonicContact OE2-NZ 2.64Å; E97-K99 PolarHBondContact OE2-NZ 2.86Å
100Y90.3Very high82Confident127 Ų12754.1 Ų54.150%0.49829%0.288SS..EExtended strand (participates in β ladder)trans-121.3104.3-166.8-49.2-66.6000111.1V25 G27 S28 F29 L102V25-Y100 HydrophobicContact CG2-CD2 3.53Å; V25-Y100 HydrophobicContact CG2-CE2 3.78Å; V25-Y100 HydrophobicContact CG2-CG 4.37Å; G27-Y100 PolarHBondContact O-N 2.87Å; S28-Y100 CarbonylContact C-O 3.58Å; S28-Y100 WeakPolarHBondContact CA-O 3.41Å; F29-Y100 PolarHBondContact N-O 2.81Å; Y100-L102 PolarHBondContact O-N 3.39Å
101P89.2Confident81.9Confident44 Ų4456.4 Ų56.429%0.28630%0.295SS..EExtended strand (participates in β ladder)trans-62.6121.8174.824-31.5000110.2M1 W6 F29 N103M1-P101 HydrophobicContact CE-CG 4.41Å; W6-P101 HydrophobicContact CB-CB 3.7Å; W6-P101 HydrophobicContact CG-CB 4.31Å; F29-P101 HydrophobicContact CE1-CB 4.08Å; F29-P101 HydrophobicContact CE2-CB 4.46Å; F29-P101 HydrophobicContact CZ-CB 3.82Å; P101-N103 PolarHBondContact O-N 2.89Å
102L88.6Confident82.3Confident20 Ų2048.2 Ų48.211%0.10526%0.259CS..  trans-84.6105.8173.3-166.3149.4000108.3H8 L19 L20 R23 F29 L30 Y100H8-L102 PolarHBondContact NE2-O 3.11Å; L19-L102 HydrophobicContact CB-CD2 4.38Å; L20-L102 HydrophobicContact CD2-CB 4.38Å; L20-L102 HydrophobicContact CD2-CD1 3.93Å; L20-L102 HydrophobicContact CG-CD1 4.45Å; R23-L102 HydrophobicContact CB-CD1 4.36Å; F29-L102 PolarHBondContact O-N 3.05Å; L30-L102 HydrophobicContact CD2-CD2 4.16Å; Y100-L102 PolarHBondContact O-N 3.39Å
103N84.3Confident82.4Confident79 Ų7944.9 Ų44.942%0.42224%0.24SC..  trans-72.3142.3-170.9-67.5-33.9000112.8R5 P101R5-N103 HydrophobicContact CB-CB 3.89Å; R5-N103 VanDerWaalsContact CB-OD1 3.28Å; R5-N103 WeakPolarHBondContact CB-OD1 3.37Å; R5-N103 CarbonylContact O-C 3.59Å; R5-N103 WeakPolarHBondContact O-CA 3.48Å; P101-N103 PolarHBondContact O-N 2.89Å
104C78.6Confident82.3Confident18 Ų1844.9 Ų44.912%0.12223%0.228CC..  trans-83.6136.7172.8-161.90000110.1R5 F7 H8 D106R5-C104 WeakPolarHBondContact O-CB 3.2Å; R5-C104 PolarHBondContact O-N 2.85Å; F7-C104 WeakPolarHBondContact O-CB 3.41Å; H8-C104 WeakPolarHBondContact CE1-CA 3.39Å; H8-C104 PolarHBondContact ND1-SG 3.33Å; C104-D106 WeakPolarHBondContact SG-CB 3.18Å; C104-D106 PolarHBondContact SG-N 3.25Å
105A75.6Confident81.9Confident45 Ų4542.3 Ų42.337%0.37222%0.217SC..  trans-100.2-1.1172.300000112.4P107A105-P107 WeakPolarHBondContact O-CD 3.48Å
106D71.9Confident81.2Confident46 Ų4646 Ų4625%0.24623%0.23CC..  trans-70.9117.6-179.1-170-11000110.4N10 C104 T108N10-D106 PolarHBondContact ND2-OD2 3.44Å; C104-D106 WeakPolarHBondContact SG-CB 3.18Å; C104-D106 PolarHBondContact SG-N 3.25Å; D106-T108 VanDerWaalsContact C-N 3.3Å; D106-T108 PolarHBondContact O-N 2.84Å; D106-T108 WeakPolarHBondContact OD1-CG2 3.22Å; D106-T108 PolarHBondContact OD1-N 2.94Å; D106-T108 PolarHBondContact OD1-OG1 2.95Å; D106-T108 VanDerWaalsContact OD1-OG1 3.14Å; D106-T108 PolarHBondContact OD2-OG1 2.76Å
107P71.8Confident80.7Confident13 Ų1346.7 Ų46.78%0.08423%0.234CC..G310 helixtrans-79.7-6.6-178.436.6-41.1000113.2A105 S109 E110 W112 F113 L190A105-P107 WeakPolarHBondContact O-CD 3.48Å; P107-S109 PolarHBondContact O-N 3.48Å; P107-E110 VanDerWaalsContact O-CB 3.22Å; P107-E110 WeakPolarHBondContact O-CB 3.47Å; P107-E110 PolarHBondContact O-N 2.93Å; P107-W112 HydrophobicContact CB-CH2 4.32Å; P107-F113 HydrophobicContact CB-CB 4.3Å; P107-F113 HydrophobicContact CB-CD1 4.38Å; P107-F113 HydrophobicContact CB-CD2 3.78Å; P107-F113 HydrophobicContact CB-CE2 4.16Å; P107-F113 HydrophobicContact CB-CG 3.89Å; P107-F113 HydrophobicContact CG-CD1 4.26Å; P107-F113 HydrophobicContact CG-CD2 3.88Å; P107-F113 HydrophobicContact CG-CE1 4.12Å; P107-F113 HydrophobicContact CG-CE2 3.72Å; P107-F113 HydrophobicContact CG-CG 4.14Å; P107-F113 HydrophobicContact CG-CZ 3.85Å; P107-F113 VanDerWaalsContact O-CB 3.31Å; P107-F113 WeakPolarHBondContact O-CB 3.41Å; P107-L190 HydrophobicContact CB-CB 4.34Å; P107-L190 HydrophobicContact CB-CD1 4.13Å; P107-L190 HydrophobicContact CG-CD1 3.97Å
108T68.6Low80.3Confident42 Ų4244.1 Ų44.126%0.25822%0.224SC..G310 helixtrans-61.9-23-16858.20000114.9N10 D106 F113N10-T108 PolarHBondContact ND2-OG1 2.71Å; D106-T108 VanDerWaalsContact C-N 3.3Å; D106-T108 PolarHBondContact O-N 2.84Å; D106-T108 WeakPolarHBondContact OD1-CG2 3.22Å; D106-T108 PolarHBondContact OD1-N 2.94Å; D106-T108 PolarHBondContact OD1-OG1 2.95Å; D106-T108 VanDerWaalsContact OD1-OG1 3.14Å; D106-T108 PolarHBondContact OD2-OG1 2.76Å; T108-F113 HydrophobicContact CG2-CE1 4.17Å
109S65.8Low80Confident8 Ų844.8 Ų44.86%0.05623%0.231CC..G310 helixtrans-90.41.417654.40000113.9P107P107-S109 PolarHBondContact O-N 3.48Å
110E76.3Confident79.8Confident29 Ų2949.1 Ų49.114%0.13625%0.25CC..SBendtrans-82.2129.7179.2-67.3-70.5172.700110.8P107 W112 F113 T191P107-E110 VanDerWaalsContact O-CB 3.22Å; P107-E110 WeakPolarHBondContact O-CB 3.47Å; P107-E110 PolarHBondContact O-N 2.93Å; E110-W112 HydrophobicContact CB-CD2 4.02Å; E110-W112 HydrophobicContact CB-CG 4.44Å; E110-W112 HydrophobicContact CB-CH2 4.27Å; E110-W112 HydrophobicContact CB-CZ2 3.69Å; E110-W112 HydrophobicContact CG-CH2 4.23Å; E110-W112 HydrophobicContact CG-CZ2 3.56Å; E110-W112 PolarHBondContact O-N 3.45Å; E110-W112 PolarHBondContact OE2-NE1 2.82Å; E110-F113 HydrophobicContact CB-CB 4.16Å; E110-F113 PolarHBondContact O-N 3.38Å; E110-T191 WeakPolarHBondContact OE1-CG2 3.32Å; E110-T191 PolarHBondContact OE1-OG1 2.9Å
111R77.9Confident79.5Confident102 Ų10248 Ų4839%0.38525%0.249SC..THydrogen-bonded Turntrans-56.5-25.1-178.2-74.3-173.871.31776.3114.8P215 T253R111-P215 HydrophobicContact CB-CB 4.03Å; R111-P215 HydrophobicContact CB-CG 4.25Å; R111-T253 HydrophobicContact CB-CG2 4.22Å; R111-T253 HydrophobicContact CG-CG2 3.29Å
112W85.6Confident79.4Confident5 Ų545.9 Ų45.92%0.01924%0.235CC..THydrogen-bonded Turntrans-93-7-17947.8-95000112.2P107 E110 H114 F135 L136 V137 L190 V194 P215P107-W112 HydrophobicContact CB-CH2 4.32Å; E110-W112 HydrophobicContact CB-CD2 4.02Å; E110-W112 HydrophobicContact CB-CG 4.44Å; E110-W112 HydrophobicContact CB-CH2 4.27Å; E110-W112 HydrophobicContact CB-CZ2 3.69Å; E110-W112 HydrophobicContact CG-CH2 4.23Å; E110-W112 HydrophobicContact CG-CZ2 3.56Å; E110-W112 PolarHBondContact O-N 3.45Å; E110-W112 PolarHBondContact OE2-NE1 2.82Å; W112-H114 PolarHBondContact O-CD2 2.89Å; W112-F135 HydrophobicContact CB-CD2 4Å; W112-F135 HydrophobicContact CB-CE2 3.45Å; W112-F135 VanDerWaalsContact CB-CE2 3.45Å; W112-F135 HydrophobicContact CB-CZ 4.05Å; W112-F135 HydrophobicContact CD2-CE2 4.19Å; W112-F135 HydrophobicContact CG-CD2 4.5Å; W112-F135 AromaticContact CG-CE2 3.58Å; W112-F135 HydrophobicContact CG-CE2 3.58Å; W112-F135 HydrophobicContact CG-CZ 4.1Å; W112-L136 CarbonylContact O-C 3.46Å; W112-L136 VanDerWaalsContact O-CA 3.25Å; W112-L136 WeakPolarHBondContact O-CA 3.19Å; W112-V137 HydrophobicContact CD2-CG2 4.43Å; W112-V137 HydrophobicContact CE3-CB 3.52Å; W112-V137 HydrophobicContact CE3-CG2 3.33Å; W112-V137 HydrophobicContact CZ3-CB 3.57Å; W112-V137 HydrophobicContact CZ3-CG1 4.12Å; W112-V137 HydrophobicContact CZ3-CG2 3.47Å; W112-V137 VanDerWaalsContact CZ3-CG2 3.47Å; W112-V137 PolarHBondContact O-N 2.87Å; W112-L190 HydrophobicContact CH2-CB 3.86Å; W112-L190 HydrophobicContact CZ3-CB 4.37Å; W112-V194 HydrophobicContact CD2-CG1 4.3Å; W112-V194 HydrophobicContact CD2-CG2 4.26Å; W112-V194 HydrophobicContact CE3-CG2 4.1Å; W112-V194 HydrophobicContact CH2-CB 4.33Å; W112-V194 HydrophobicContact CH2-CG2 3.74Å; W112-V194 HydrophobicContact CZ2-CB 4.01Å; W112-V194 HydrophobicContact CZ2-CG1 4.26Å; W112-V194 HydrophobicContact CZ2-CG2 3.9Å; W112-V194 HydrophobicContact CZ3-CG2 3.85Å; W112-P215 HydrophobicContact CB-CB 3.85Å; W112-P215 HydrophobicContact CB-CG 4.12Å
113F82.9Confident79.6Confident29 Ų2948.9 Ų48.913%0.12725%0.249CC..BIsolated β-bridgetrans-92.2125.3-179.8-173.3-100000110.7P107 T108 E110 V137 F147 L190P107-F113 HydrophobicContact CB-CB 4.3Å; P107-F113 HydrophobicContact CB-CD1 4.38Å; P107-F113 HydrophobicContact CB-CD2 3.78Å; P107-F113 HydrophobicContact CB-CE2 4.16Å; P107-F113 HydrophobicContact CB-CG 3.89Å; P107-F113 HydrophobicContact CG-CD1 4.26Å; P107-F113 HydrophobicContact CG-CD2 3.88Å; P107-F113 HydrophobicContact CG-CE1 4.12Å; P107-F113 HydrophobicContact CG-CE2 3.72Å; P107-F113 HydrophobicContact CG-CG 4.14Å; P107-F113 HydrophobicContact CG-CZ 3.85Å; P107-F113 VanDerWaalsContact O-CB 3.31Å; P107-F113 WeakPolarHBondContact O-CB 3.41Å; T108-F113 HydrophobicContact CG2-CE1 4.17Å; E110-F113 HydrophobicContact CB-CB 4.16Å; E110-F113 PolarHBondContact O-N 3.38Å; F113-V137 WeakPolarHBondContact CA-O 3.45Å; F113-V137 HydrophobicContact CD2-CB 4.35Å; F113-V137 HydrophobicContact CD2-CG1 4.22Å; F113-F147 AromaticContact CE2-CD1 3.84Å; F113-F147 HydrophobicContact CE2-CD1 3.84Å; F113-F147 AromaticContact CE2-CE1 3.72Å; F113-F147 HydrophobicContact CE2-CE1 3.72Å; F113-F147 HydrophobicContact CZ-CD1 4.45Å; F113-F147 AromaticContact CZ-CE1 3.96Å; F113-F147 HydrophobicContact CZ-CE1 3.96Å; F113-L190 HydrophobicContact CD2-CD1 4.35Å; F113-L190 HydrophobicContact CE2-CD1 4.05Å
114H79.4Confident79.8Confident43 Ų4351.1 Ų51.120%0.19926%0.255CS..  trans-1177.8-175.2-74.5-129.3000112.9W112 H116 L117 V137 T218W112-H114 PolarHBondContact O-CD2 2.89Å; H114-H116 PolarHBondContact O-N 3.29Å; H114-L117 HydrophobicContact CB-CB 4.32Å; H114-L117 HydrophobicContact CB-CD2 3.96Å; H114-V137 PolarHBondContact N-O 3.11Å; H114-T218 WeakPolarHBondContact CE1-CG2 3.35Å
115G78.2Confident80.1Confident13 Ų1352.1 Ų52.113%0.13426%0.259CS..SBendtrans52.2-126.1179.600000112.2L117 R138 E139G115-L117 PolarHBondContact O-N 3.12Å; G115-L117 VanDerWaalsContact O-N 3.08Å; G115-R138 CarbonylContact O-C 3.48Å; G115-R138 WeakPolarHBondContact O-CA 3.4Å; G115-E139 PolarHBondContact O-N 3.23Å
116H73.9Confident80.7Confident139 Ų13950 Ų5064%0.64424%0.241SC*.SBendtrans-75.794.9-178.5-155.278.6000112H114 E139H114-H116 PolarHBondContact O-N 3.29Å; H116-E139 IonicContact CG-OE2 2.7Å; H116-E139 IonicContact ND1-OE2 2.77Å; H116-E139 PolarHBondContact ND1-OE2 3.18Å; H116-E139 VanDerWaalsContact ND1-OE2 3.17Å
117L79.6Confident81.5Confident21 Ų2151.7 Ų51.711%0.1125%0.253CS..  trans-137.7131.3177.8-171.872.2000109.3H114 G115 E121 A122 L125 L136 R138H114-L117 HydrophobicContact CB-CB 4.32Å; H114-L117 HydrophobicContact CB-CD2 3.96Å; G115-L117 PolarHBondContact O-N 3.12Å; G115-L117 VanDerWaalsContact O-N 3.08Å; L117-E121 HydrophobicContact CD1-CB 3.62Å; L117-E121 HydrophobicContact CG-CB 4.1Å; L117-A122 HydrophobicContact CD2-CB 3.83Å; L117-A122 HydrophobicContact CG-CB 4.36Å; L117-L125 HydrophobicContact CD1-CD1 4.05Å; L117-L125 HydrophobicContact CD2-CD1 4.02Å; L117-L136 HydrophobicContact CD2-CD1 4.01Å; L117-L136 HydrophobicContact CD2-CD2 4.14Å; L117-R138 HydrophobicContact CB-CB 3.91Å; L117-R138 VanDerWaalsContact O-CD 3.3Å; L117-R138 WeakPolarHBondContact O-CD 3.14Å
118S83Confident82.1Confident19 Ų1956.7 Ų56.713%0.13328%0.275CS..  trans-72.6160.4177.172.60000112.1K120 E121 A122 Q141S118-K120 VanDerWaalsContact C-N 3.3Å; S118-K120 PolarHBondContact O-N 3.13Å; S118-E121 WeakPolarHBondContact CB-OE2 3.47Å; S118-E121 PolarHBondContact N-OE2 3.48Å; S118-E121 PolarHBondContact O-N 3.46Å; S118-E121 WeakPolarHBondContact OG-CB 3.27Å; S118-E121 WeakPolarHBondContact OG-CG 3.24Å; S118-E121 PolarHBondContact OG-N 2.76Å; S118-E121 VanDerWaalsContact OG-N 3.15Å; S118-E121 PolarHBondContact OG-OE2 3.05Å; S118-A122 WeakPolarHBondContact O-CB 3.49Å; S118-A122 PolarHBondContact O-N 3.46Å; S118-Q141 VanDerWaalsContact CB-NE2 3.34Å; S118-Q141 VanDerWaalsContact CB-OE1 3.24Å
119G85.5Confident82.7Confident15 Ų1558 Ų5816%0.15528%0.278CS..Hα-helixtrans-58.1-42.7174.500000112.7A122 E123 R138G119-A122 WeakPolarHBondContact O-CB 3.4Å; G119-A122 PolarHBondContact O-N 3.32Å; G119-E123 WeakPolarHBondContact O-CG 3.39Å; G119-E123 PolarHBondContact O-N 3.01Å; G119-R138 VanDerWaalsContact CA-CZ 3.48Å; G119-R138 VanDerWaalsContact CA-NH2 3.31Å
120K88.9Confident83.6Confident175 Ų17558 Ų5876%0.76128%0.279SS*.Hα-helixtrans-66-41.2179.4-67.6-176.6178-1800112.6S118 E123 K124S118-K120 VanDerWaalsContact C-N 3.3Å; S118-K120 PolarHBondContact O-N 3.13Å; K120-E123 PolarHBondContact O-N 3.25Å; K120-K124 WeakPolarHBondContact O-CB 3.47Å; K120-K124 PolarHBondContact O-N 2.77Å
121E83.8Confident84.1Confident102 Ų10262.3 Ų62.348%0.47730%0.298SS..Hα-helixtrans-66.9-39.8175.6-69.4160.414200111.3L117 S118 K124 L125L117-E121 HydrophobicContact CD1-CB 3.62Å; L117-E121 HydrophobicContact CG-CB 4.1Å; S118-E121 WeakPolarHBondContact CB-OE2 3.47Å; S118-E121 PolarHBondContact N-OE2 3.48Å; S118-E121 PolarHBondContact O-N 3.46Å; S118-E121 WeakPolarHBondContact OG-CB 3.27Å; S118-E121 WeakPolarHBondContact OG-CG 3.24Å; S118-E121 PolarHBondContact OG-N 2.76Å; S118-E121 VanDerWaalsContact OG-N 3.15Å; S118-E121 PolarHBondContact OG-OE2 3.05Å; E121-K124 PolarHBondContact O-N 3.45Å; E121-L125 WeakPolarHBondContact O-CB 3.45Å; E121-L125 VanDerWaalsContact O-CG 3.29Å; E121-L125 WeakPolarHBondContact O-CG 3.34Å; E121-L125 PolarHBondContact O-N 3.14Å
122A87.2Confident84.7Confident0 Ų059.5 Ų59.50%029%0.289CS..Hα-helixtrans-62-45.1174.600000112.3L117 S118 G119 L125 L126 L136L117-A122 HydrophobicContact CD2-CB 3.83Å; L117-A122 HydrophobicContact CG-CB 4.36Å; S118-A122 WeakPolarHBondContact O-CB 3.49Å; S118-A122 PolarHBondContact O-N 3.46Å; G119-A122 WeakPolarHBondContact O-CB 3.4Å; G119-A122 PolarHBondContact O-N 3.32Å; A122-L125 PolarHBondContact O-N 3.49Å; A122-L126 VanDerWaalsContact O-CB 3.3Å; A122-L126 WeakPolarHBondContact O-CB 3.3Å; A122-L126 WeakPolarHBondContact O-CG 3.28Å; A122-L126 PolarHBondContact O-N 3.16Å; A122-L136 HydrophobicContact CB-CD1 3.98Å; A122-L136 HydrophobicContact CB-CD2 4.27Å
123E92.6Very high84.9Confident84 Ų8459.3 Ų59.339%0.39329%0.288SS..Hα-helixtrans-59.2-47.7174.1-74.8178.3179.100111.3G119 K120 L126 T127 V167 H169G119-E123 WeakPolarHBondContact O-CG 3.39Å; G119-E123 PolarHBondContact O-N 3.01Å; K120-E123 PolarHBondContact O-N 3.25Å; E123-L126 PolarHBondContact O-N 2.71Å; E123-T127 VanDerWaalsContact O-CB 3.24Å; E123-T127 WeakPolarHBondContact O-CB 3.37Å; E123-T127 PolarHBondContact O-N 3.44Å; E123-T127 PolarHBondContact O-OG1 3.16Å; E123-V167 HydrophobicContact CG-CB 4.06Å; E123-V167 HydrophobicContact CG-CG1 3.97Å; E123-H169 WeakPolarHBondContact CG-NE2 3.22Å; E123-H169 IonicContact OE1-CD2 3.03Å; E123-H169 IonicContact OE1-NE2 2.72Å; E123-H169 PolarHBondContact OE1-NE2 3.18Å
124K88.5Confident85.3Confident126 Ų12658.1 Ų58.155%0.54828%0.283SS..Hα-helixtrans-56.7-52.6177-177.4-178.6176.6-174.80111.2K120 E121 L126 T127 E128K120-K124 WeakPolarHBondContact O-CB 3.47Å; K120-K124 PolarHBondContact O-N 2.77Å; E121-K124 PolarHBondContact O-N 3.45Å; K124-L126 PolarHBondContact O-N 2.83Å; K124-T127 PolarHBondContact O-N 3.1Å; K124-E128 WeakPolarHBondContact CE-OE1 3.36Å; K124-E128 HydrophobicContact CG-CG 4.4Å; K124-E128 WeakPolarHBondContact CG-OE1 3.49Å; K124-E128 IonicContact NZ-OE1 3.93Å; K124-E128 WeakPolarHBondContact O-CB 3.07Å; K124-E128 WeakPolarHBondContact O-CG 3.07Å; K124-E128 PolarHBondContact O-N 2.75Å
125L84.9Confident86Confident39 Ų3956 Ų5620%0.20427%0.274CS..Hα-helixtrans-61.7-44-179.8-76.6175.5000112.9L117 E121 A122 T127 K129 L216L117-L125 HydrophobicContact CD1-CD1 4.05Å; L117-L125 HydrophobicContact CD2-CD1 4.02Å; E121-L125 WeakPolarHBondContact O-CB 3.45Å; E121-L125 VanDerWaalsContact O-CG 3.29Å; E121-L125 WeakPolarHBondContact O-CG 3.34Å; E121-L125 PolarHBondContact O-N 3.14Å; A122-L125 PolarHBondContact O-N 3.49Å; L125-T127 VanDerWaalsContact C-N 3.29Å; L125-T127 PolarHBondContact O-N 2.86Å; L125-K129 WeakPolarHBondContact O-CB 3.46Å; L125-K129 PolarHBondContact O-N 3.36Å; L125-L216 HydrophobicContact CB-CD2 3.72Å
126L89.3Confident86.7Confident0 Ų055.4 Ų55.40%027%0.267CS..Hα-helixtrans-66.8-32.6176.9-79.2164.8000111.8A122 E123 K124 G130 S134 L136 R152 V167 L216A122-L126 VanDerWaalsContact O-CB 3.3Å; A122-L126 WeakPolarHBondContact O-CB 3.3Å; A122-L126 WeakPolarHBondContact O-CG 3.28Å; A122-L126 PolarHBondContact O-N 3.16Å; E123-L126 PolarHBondContact O-N 2.71Å; K124-L126 PolarHBondContact O-N 2.83Å; L126-G130 WeakPolarHBondContact O-CA 3.4Å; L126-G130 PolarHBondContact O-N 3.21Å; L126-S134 WeakPolarHBondContact CD2-O 3.44Å; L126-L136 HydrophobicContact CD1-CD2 4.11Å; L126-L136 HydrophobicContact CD1-CG 4.24Å; L126-L136 HydrophobicContact CD2-CD2 4.42Å; L126-L136 HydrophobicContact CG-CD2 3.95Å; L126-R152 HydrophobicContact CB-CB 4.4Å; L126-R152 HydrophobicContact CD2-CB 4.25Å; L126-R152 WeakPolarHBondContact O-CD 3.45Å; L126-R152 PolarHBondContact O-NH1 2.79Å; L126-V167 HydrophobicContact CB-CG2 3.85Å; L126-V167 HydrophobicContact CD1-CG1 3.66Å; L126-V167 HydrophobicContact CD1-CG2 4.29Å; L126-L216 HydrophobicContact CD2-CB 4.4Å; L126-L216 HydrophobicContact CD2-CD1 4.2Å; L126-L216 HydrophobicContact CD2-CD2 4.41Å; L126-L216 HydrophobicContact CG-CD2 4.43Å
127T88Confident87.6Confident81 Ų8148.8 Ų48.850%0.49724%0.237SC..Hα-helixtrans-74.7-43.4177.7-56.30000111.7E123 K124 L125 R152E123-T127 VanDerWaalsContact O-CB 3.24Å; E123-T127 WeakPolarHBondContact O-CB 3.37Å; E123-T127 PolarHBondContact O-N 3.44Å; E123-T127 PolarHBondContact O-OG1 3.16Å; K124-T127 PolarHBondContact O-N 3.1Å; L125-T127 VanDerWaalsContact C-N 3.29Å; L125-T127 PolarHBondContact O-N 2.86Å; T127-R152 VanDerWaalsContact C-NH1 3.34Å; T127-R152 PolarHBondContact O-NH1 3.42Å
128E84.2Confident88Confident118 Ų11848.6 Ų48.655%0.55123%0.234SC*.Hα-helixtrans-75.6-42.4-178.4-71.1172.8175.900112.7K124K124-E128 WeakPolarHBondContact CE-OE1 3.36Å; K124-E128 HydrophobicContact CG-CG 4.4Å; K124-E128 WeakPolarHBondContact CG-OE1 3.49Å; K124-E128 IonicContact NZ-OE1 3.93Å; K124-E128 WeakPolarHBondContact O-CB 3.07Å; K124-E128 WeakPolarHBondContact O-CG 3.07Å; K124-E128 PolarHBondContact O-N 2.75Å
129K81.6Confident87.9Confident70 Ų7051.4 Ų51.430%0.30425%0.245SC..Hα-helixtrans-116.8-17-169.4-59.1-173.4179.6-168.20114.2L125 L216L125-K129 WeakPolarHBondContact O-CB 3.46Å; L125-K129 PolarHBondContact O-N 3.36Å; K129-L216 HydrophobicContact CB-CD1 4Å
130G83.8Confident87.9Confident9 Ų951.1 Ų51.19%0.09324%0.241CC..  trans-78.2168-179.500000112.8L126 R152L126-G130 WeakPolarHBondContact O-CA 3.4Å; L126-G130 PolarHBondContact O-N 3.21Å; G130-R152 PolarHBondContact O-NH1 3.38Å
131K87.6Confident87.5Confident119 Ų11947.9 Ų47.952%0.51723%0.228SC..  trans-135.7178.7167.764.2-173.8179.6174.10108.5G133 S134K131-G133 PolarHBondContact O-N 2.94Å; K131-G133 VanDerWaalsContact O-N 3.16Å; K131-S134 PolarHBondContact N-OG 3.31Å; K131-S134 WeakPolarHBondContact O-CB 3.18Å; K131-S134 PolarHBondContact O-N 3.41Å; K131-S134 PolarHBondContact O-OG 2.85Å
132H89.6Confident87.4Confident43 Ų4347.4 Ų47.420%0.19924%0.236CC..THydrogen-bonded Turntrans-48.4124.7175.5178.883.6000112S134 G154 D155 K213 Q214H132-S134 VanDerWaalsContact C-N 3.32Å; H132-G154 VanDerWaalsContact CB-O 3.32Å; H132-G154 WeakPolarHBondContact CB-O 3.44Å; H132-G154 PolarHBondContact ND1-N 3.13Å; H132-G154 PolarHBondContact ND1-O 3.17Å; H132-D155 IonicContact CG-OD1 3.05Å; H132-D155 IonicContact ND1-OD1 3.11Å; H132-K213 PolarHBondContact CD2-NZ 3.45Å; H132-K213 VanDerWaalsContact CD2-NZ 3.26Å; H132-K213 PolarHBondContact NE2-NZ 3.48Å; H132-Q214 PolarHBondContact O-NE2 2.66Å
133G89.7Confident87.1Confident0 Ų052.4 Ų52.40%026%0.26CS..THydrogen-bonded Turntrans76.612.3-178.100000115.1K131 R152 Q211 K213 Q214K131-G133 PolarHBondContact O-N 2.94Å; K131-G133 VanDerWaalsContact O-N 3.16Å; G133-R152 WeakPolarHBondContact CA-O 3.23Å; G133-R152 PolarHBondContact N-O 3.23Å; G133-Q211 WeakPolarHBondContact CA-O 3.25Å; G133-K213 PolarHBondContact O-N 3.38Å; G133-Q214 VanDerWaalsContact C-NE2 3.31Å; G133-Q214 PolarHBondContact O-N 2.91Å; G133-Q214 VanDerWaalsContact O-N 3.14Å
134S91.9Very high86.4Confident4 Ų454.5 Ų54.53%0.02828%0.281CS..EExtended strand (participates in β ladder)trans-71.1135.4168.8-78.90000110.1L126 K131 H132 R152 Q214L126-S134 WeakPolarHBondContact CD2-O 3.44Å; K131-S134 PolarHBondContact N-OG 3.31Å; K131-S134 WeakPolarHBondContact O-CB 3.18Å; K131-S134 PolarHBondContact O-N 3.41Å; K131-S134 PolarHBondContact O-OG 2.85Å; H132-S134 VanDerWaalsContact C-N 3.32Å; S134-R152 PolarHBondContact O-N 3.14Å; S134-Q214 CarbonylContact C-O 3.59Å; S134-Q214 VanDerWaalsContact CA-O 3.26Å; S134-Q214 WeakPolarHBondContact CA-O 3.39Å; S134-Q214 PolarHBondContact OG-NE2 2.89Å
135F94.9Very high85.8Confident0 Ų051 Ų510%028%0.28CS..EExtended strand (participates in β ladder)trans-140.6158.9-179.573.4-84.1000113.1W112 L149 S150 V151 V194 K198 L212 Q214 P215 L216W112-F135 HydrophobicContact CB-CD2 4Å; W112-F135 HydrophobicContact CB-CE2 3.45Å; W112-F135 VanDerWaalsContact CB-CE2 3.45Å; W112-F135 HydrophobicContact CB-CZ 4.05Å; W112-F135 HydrophobicContact CD2-CE2 4.19Å; W112-F135 HydrophobicContact CG-CD2 4.5Å; W112-F135 AromaticContact CG-CE2 3.58Å; W112-F135 HydrophobicContact CG-CE2 3.58Å; W112-F135 HydrophobicContact CG-CZ 4.1Å; F135-L149 HydrophobicContact CB-CD1 4.09Å; F135-L149 HydrophobicContact CD2-CD1 3.78Å; F135-L149 HydrophobicContact CG-CD1 4.34Å; F135-S150 CarbonylContact C-O 3.58Å; F135-S150 VanDerWaalsContact CA-O 3.23Å; F135-S150 WeakPolarHBondContact CA-O 3.46Å; F135-V151 HydrophobicContact CB-CB 4.44Å; F135-V151 HydrophobicContact CB-CG1 4.32Å; F135-V151 HydrophobicContact CB-CG2 4.03Å; F135-V194 HydrophobicContact CE2-CG1 3.7Å; F135-V194 HydrophobicContact CZ-CG1 3.96Å; F135-K198 HydrophobicContact CZ-CD 4.21Å; F135-L212 HydrophobicContact CB-CD2 3.82Å; F135-L212 HydrophobicContact CD1-CB 3.76Å; F135-L212 HydrophobicContact CD1-CD2 4.15Å; F135-L212 HydrophobicContact CD1-CG 4.49Å; F135-L212 HydrophobicContact CD2-CD2 4.32Å; F135-L212 HydrophobicContact CE1-CB 3.81Å; F135-L212 HydrophobicContact CG-CB 4.26Å; F135-L212 HydrophobicContact CG-CD2 3.85Å; F135-L212 HydrophobicContact CZ-CB 4.34Å; F135-Q214 VanDerWaalsContact CD1-C 3.48Å; F135-Q214 WeakPolarHBondContact CD1-O 3.49Å; F135-Q214 PolarHBondContact N-O 2.89Å; F135-P215 HydrophobicContact CE1-CG 4.35Å; F135-P215 HydrophobicContact CZ-CG 4.17Å; F135-P215 CarbonylContact O-C 3.57Å; F135-P215 WeakPolarHBondContact O-CA 3.33Å; F135-L216 PolarHBondContact O-N 2.78Å
136L92.7Very high86Confident0 Ų050.4 Ų50.40%028%0.277CS..EExtended strand (participates in β ladder)trans-145.9157.8169.663.485.7000110.3W112 L117 A122 L126 R138 S150 L216W112-L136 CarbonylContact O-C 3.46Å; W112-L136 VanDerWaalsContact O-CA 3.25Å; W112-L136 WeakPolarHBondContact O-CA 3.19Å; L117-L136 HydrophobicContact CD2-CD1 4.01Å; L117-L136 HydrophobicContact CD2-CD2 4.14Å; A122-L136 HydrophobicContact CB-CD1 3.98Å; A122-L136 HydrophobicContact CB-CD2 4.27Å; L126-L136 HydrophobicContact CD1-CD2 4.11Å; L126-L136 HydrophobicContact CD1-CG 4.24Å; L126-L136 HydrophobicContact CD2-CD2 4.42Å; L126-L136 HydrophobicContact CG-CD2 3.95Å; L136-R138 HydrophobicContact CD1-CB 4.23Å; L136-R138 HydrophobicContact CD1-CG 4.26Å; L136-S150 PolarHBondContact N-O 2.85Å; L136-S150 PolarHBondContact O-N 2.82Å; L136-L216 HydrophobicContact CB-CB 4.46Å; L136-L216 HydrophobicContact CD2-CB 4.44Å; L136-L216 HydrophobicContact CD2-CD2 3.64Å
137V92.3Very high86.2Confident0 Ų051.7 Ų51.70%028%0.283CS..EExtended strand (participates in β ladder)trans-117.6136.6171.3-179.40000108.6W112 F113 H114 F147 V148 L149 I172 L190 V194W112-V137 HydrophobicContact CD2-CG2 4.43Å; W112-V137 HydrophobicContact CE3-CB 3.52Å; W112-V137 HydrophobicContact CE3-CG2 3.33Å; W112-V137 HydrophobicContact CZ3-CB 3.57Å; W112-V137 HydrophobicContact CZ3-CG1 4.12Å; W112-V137 HydrophobicContact CZ3-CG2 3.47Å; W112-V137 VanDerWaalsContact CZ3-CG2 3.47Å; W112-V137 PolarHBondContact O-N 2.87Å; F113-V137 WeakPolarHBondContact CA-O 3.45Å; F113-V137 HydrophobicContact CD2-CB 4.35Å; F113-V137 HydrophobicContact CD2-CG1 4.22Å; H114-V137 PolarHBondContact N-O 3.11Å; V137-F147 HydrophobicContact CG1-CB 4.09Å; V137-V148 WeakPolarHBondContact CA-O 3.34Å; V137-L149 HydrophobicContact CG2-CB 4.32Å; V137-L149 HydrophobicContact CG2-CD1 3.84Å; V137-I172 HydrophobicContact CG1-CD1 4.09Å; V137-I172 HydrophobicContact CG2-CD1 4.47Å; V137-L190 HydrophobicContact CG1-CD1 4.32Å; V137-V194 HydrophobicContact CG2-CG2 4.06Å
138R88.3Confident86.5Confident17 Ų1748.1 Ų48.16%0.06426%0.261CS..EExtended strand (participates in β ladder)trans-137.5162.7-177.561.1-169.6-178.871.2-1110.4G115 L117 G119 L136 F147 V148 S150 H169G115-R138 CarbonylContact O-C 3.48Å; G115-R138 WeakPolarHBondContact O-CA 3.4Å; L117-R138 HydrophobicContact CB-CB 3.91Å; L117-R138 VanDerWaalsContact O-CD 3.3Å; L117-R138 WeakPolarHBondContact O-CD 3.14Å; G119-R138 VanDerWaalsContact CA-CZ 3.48Å; G119-R138 VanDerWaalsContact CA-NH2 3.31Å; L136-R138 HydrophobicContact CD1-CB 4.23Å; L136-R138 HydrophobicContact CD1-CG 4.26Å; R138-F147 CarbonylContact O-C 3.58Å; R138-F147 VanDerWaalsContact O-CA 3.27Å; R138-F147 WeakPolarHBondContact O-CA 3.44Å; R138-F147 WeakPolarHBondContact O-CB 3.38Å; R138-V148 HydrophobicContact CG-CB 4.06Å; R138-V148 PolarHBondContact N-O 2.9Å; R138-V148 PolarHBondContact O-N 3.48Å; R138-S150 PolarHBondContact NE-OG 3.39Å; R138-S150 VanDerWaalsContact NE-OG 3.14Å; R138-H169 PolarHBondContact NH2-ND1 2.99Å
139E81.7Confident87.1Confident77 Ų7742.5 Ų42.536%0.3624%0.235SC..EExtended strand (participates in β ladder)trans-65.5145.1171.3-68.4176.7178.700111G115 H116 Q141 F147G115-E139 PolarHBondContact O-N 3.23Å; H116-E139 IonicContact CG-OE2 2.7Å; H116-E139 IonicContact ND1-OE2 2.77Å; H116-E139 PolarHBondContact ND1-OE2 3.18Å; H116-E139 VanDerWaalsContact ND1-OE2 3.17Å; E139-Q141 PolarHBondContact O-N 3.17Å; E139-F147 HydrophobicContact CG-CD1 4.32Å; E139-F147 HydrophobicContact CG-CE1 4.05Å
140S83.9Confident87.7Confident9 Ų939.1 Ų39.16%0.06322%0.22CC..  trans-77.7120.7173.6-177.80000110.1S142 H143 D146S140-S142 VanDerWaalsContact C-N 3.28Å; S140-H143 WeakPolarHBondContact CB-O 3.4Å; S140-H143 PolarHBondContact OG-N 2.96Å; S140-H143 VanDerWaalsContact OG-N 3.16Å; S140-D146 VanDerWaalsContact CB-O 3.24Å; S140-D146 WeakPolarHBondContact CB-O 3.24Å; S140-D146 PolarHBondContact N-O 2.93Å
141Q80.6Confident88.3Confident107 Ų10738.7 Ų38.750%0.522%0.216SC..SBendtrans-75.1-22.2173.5-67-175.3-45.100112.5S118 E139S118-Q141 VanDerWaalsContact CB-NE2 3.34Å; S118-Q141 VanDerWaalsContact CB-OE1 3.24Å; E139-Q141 PolarHBondContact O-N 3.17Å
142S81.8Confident88.5Confident92 Ų9233.9 Ų33.964%0.64319%0.194SC*.SBendtrans-88.9-30.4-176.7-490000112.6S140S140-S142 VanDerWaalsContact C-N 3.28Å
143H82.1Confident88.5Confident106 Ų10632 Ų3249%0.49119%0.186SC..SBendtrans-133.895.3-177.3-60.797.1000109.2S140 G145 D146S140-H143 WeakPolarHBondContact CB-O 3.4Å; S140-H143 PolarHBondContact OG-N 2.96Å; S140-H143 VanDerWaalsContact OG-N 3.16Å; H143-G145 PolarHBondContact O-N 3.09Å; H143-D146 HydrophobicContact CB-CB 4.01Å; H143-D146 WeakPolarHBondContact O-CB 3.39Å; H143-D146 PolarHBondContact O-N 3.4Å
144P77.6Confident87.9Confident128 Ų12833.1 Ų33.183%0.83120%0.197SC*.THydrogen-bonded Turntrans-55.7129.2179.2-26.735.3000111.9
145G74.9Confident86.5Confident52 Ų5238.3 Ų38.354%0.53622%0.224SC..THydrogen-bonded Turntrans97-18.5-175.800000114.6H143 F147 C174H143-G145 PolarHBondContact O-N 3.09Å; G145-F147 WeakPolarHBondContact O-CE2 3.48Å; G145-C174 WeakPolarHBondContact O-CB 3.25Å
146D89.3Confident84.6Confident27 Ų2743.4 Ų43.414%0.14425%0.252CS..  trans-89167.6171.3-72.6-11.1000111.5S140 H143 M171 I172 R173 C174S140-D146 VanDerWaalsContact CB-O 3.24Å; S140-D146 WeakPolarHBondContact CB-O 3.24Å; S140-D146 PolarHBondContact N-O 2.93Å; H143-D146 HydrophobicContact CB-CB 4.01Å; H143-D146 WeakPolarHBondContact O-CB 3.39Å; H143-D146 PolarHBondContact O-N 3.4Å; D146-M171 HydrophobicContact CB-SD 4.29Å; D146-I172 WeakPolarHBondContact CB-O 3.37Å; D146-R173 WeakPolarHBondContact OD1-CA 3.36Å; D146-C174 PolarHBondContact OD1-N 3.04Å
147F93Very high82.6Confident26 Ų2651.9 Ų51.911%0.11429%0.289CS..EExtended strand (participates in β ladder)trans-127.5167.8-179.3-59.4-91.4000111F113 V137 R138 E139 G145 M171 I172 Y179 L190F113-F147 AromaticContact CE2-CD1 3.84Å; F113-F147 HydrophobicContact CE2-CD1 3.84Å; F113-F147 AromaticContact CE2-CE1 3.72Å; F113-F147 HydrophobicContact CE2-CE1 3.72Å; F113-F147 HydrophobicContact CZ-CD1 4.45Å; F113-F147 AromaticContact CZ-CE1 3.96Å; F113-F147 HydrophobicContact CZ-CE1 3.96Å; V137-F147 HydrophobicContact CG1-CB 4.09Å; R138-F147 CarbonylContact O-C 3.58Å; R138-F147 VanDerWaalsContact O-CA 3.27Å; R138-F147 WeakPolarHBondContact O-CA 3.44Å; R138-F147 WeakPolarHBondContact O-CB 3.38Å; E139-F147 HydrophobicContact CG-CD1 4.32Å; E139-F147 HydrophobicContact CG-CE1 4.05Å; G145-F147 WeakPolarHBondContact O-CE2 3.48Å; F147-M171 VanDerWaalsContact O-SD 3.39Å; F147-I172 HydrophobicContact CB-CB 4Å; F147-I172 HydrophobicContact CB-CD1 4.34Å; F147-I172 HydrophobicContact CB-CG2 4.38Å; F147-I172 PolarHBondContact N-O 3.27Å; F147-I172 WeakPolarHBondContact O-CA 3.45Å; F147-I172 PolarHBondContact O-N 2.53Å; F147-I172 VanDerWaalsContact O-O 3.14Å; F147-Y179 HydrophobicContact CD2-CD1 4.32Å; F147-Y179 HydrophobicContact CD2-CE1 4.05Å; F147-Y179 HydrophobicContact CE2-CD1 4.44Å; F147-Y179 AromaticContact CE2-CE1 3.74Å; F147-Y179 HydrophobicContact CE2-CE1 3.74Å; F147-L190 HydrophobicContact CB-CD1 4.49Å; F147-L190 HydrophobicContact CB-CD2 4.39Å; F147-L190 HydrophobicContact CD1-CD1 3.76Å; F147-L190 HydrophobicContact CD2-CD1 3.97Å; F147-L190 HydrophobicContact CD2-CD2 4.08Å; F147-L190 HydrophobicContact CD2-CG 4.47Å; F147-L190 HydrophobicContact CE1-CD1 3.89Å; F147-L190 HydrophobicContact CE2-CD1 4.13Å; F147-L190 HydrophobicContact CG-CD1 3.79Å; F147-L190 HydrophobicContact CG-CD2 4.22Å; F147-L190 HydrophobicContact CZ-CD1 4.08Å
148V95.4Very high80.6Confident6 Ų655.8 Ų55.84%0.03633%0.329CS..EExtended strand (participates in β ladder)trans-134.9123.4176.7-173.80000109.6V137 R138 H169 V170 M171V137-V148 WeakPolarHBondContact CA-O 3.34Å; R138-V148 HydrophobicContact CG-CB 4.06Å; R138-V148 PolarHBondContact N-O 2.9Å; R138-V148 PolarHBondContact O-N 3.48Å; V148-H169 HydrophobicContact CG1-CB 3.84Å; V148-V170 CarbonylContact C-O 3.46Å; V148-V170 WeakPolarHBondContact CA-O 3.31Å; V148-M171 HydrophobicContact CG2-CE 4.08Å; V148-M171 HydrophobicContact CG2-SD 3.96Å
149L96.1Very high78.5Confident0 Ų064 Ų640%037%0.368CS..EExtended strand (participates in β ladder)trans-86.7116.9169169.761.2000109F135 V137 V151 H169 V170 I172 M202 L212F135-L149 HydrophobicContact CB-CD1 4.09Å; F135-L149 HydrophobicContact CD2-CD1 3.78Å; F135-L149 HydrophobicContact CG-CD1 4.34Å; V137-L149 HydrophobicContact CG2-CB 4.32Å; V137-L149 HydrophobicContact CG2-CD1 3.84Å; L149-V151 HydrophobicContact CD1-CG2 3.9Å; L149-V151 HydrophobicContact CD2-CG2 4.31Å; L149-V151 HydrophobicContact CG-CG2 3.75Å; L149-H169 CarbonylContact O-C 3.48Å; L149-H169 WeakPolarHBondContact O-CA 3.22Å; L149-V170 HydrophobicContact CB-CB 4.3Å; L149-V170 PolarHBondContact N-O 3.4Å; L149-V170 PolarHBondContact O-N 2.94Å; L149-I172 HydrophobicContact CB-CD1 3.78Å; L149-I172 HydrophobicContact CB-CG1 4.37Å; L149-M202 HydrophobicContact CD2-CE 3.57Å; L149-L212 HydrophobicContact CD1-CD2 4.14Å; L149-L212 HydrophobicContact CD2-CD1 4.1Å; L149-L212 HydrophobicContact CD2-CD2 4.15Å
150S95.4Very high76.7Confident0 Ų064.7 Ų64.70%038%0.381CS..EExtended strand (participates in β ladder)trans-107.9122.9179.7-50.10000109.2F135 L136 R138 T168 H169F135-S150 CarbonylContact C-O 3.58Å; F135-S150 VanDerWaalsContact CA-O 3.23Å; F135-S150 WeakPolarHBondContact CA-O 3.46Å; L136-S150 PolarHBondContact N-O 2.85Å; L136-S150 PolarHBondContact O-N 2.82Å; R138-S150 PolarHBondContact NE-OG 3.39Å; R138-S150 VanDerWaalsContact NE-OG 3.14Å; S150-T168 CarbonylContact C-O 3.56Å; S150-T168 WeakPolarHBondContact CA-O 3.38Å; S150-H169 WeakPolarHBondContact CB-ND1 3.14Å; S150-H169 PolarHBondContact OG-CE1 3.44Å; S150-H169 PolarHBondContact OG-ND1 2.76Å
151V95.3Very high74.9Confident0 Ų073 Ų730%043%0.425CS..EExtended strand (participates in β ladder)trans-129.7128.5-171.2-170.30000110.4F135 L149 T153 V167 T168 L212F135-V151 HydrophobicContact CB-CB 4.44Å; F135-V151 HydrophobicContact CB-CG1 4.32Å; F135-V151 HydrophobicContact CB-CG2 4.03Å; L149-V151 HydrophobicContact CD1-CG2 3.9Å; L149-V151 HydrophobicContact CD2-CG2 4.31Å; L149-V151 HydrophobicContact CG-CG2 3.75Å; V151-T153 HydrophobicContact CG1-CG2 4.32Å; V151-V167 CarbonylContact O-C 3.59Å; V151-V167 WeakPolarHBondContact O-CA 3.34Å; V151-T168 PolarHBondContact N-O 3Å; V151-T168 PolarHBondContact O-N 2.88Å; V151-L212 HydrophobicContact CB-CD2 4.47Å; V151-L212 HydrophobicContact CG1-CD2 4.04Å; V151-L212 HydrophobicContact CG2-CD2 3.53Å
152R92.9Very high73.5Confident17 Ų1775.7 Ų75.76%0.06444%0.443CS..EExtended strand (participates in β ladder)trans-85.1127.6170.9-179.8168.7173.4173.7-1.4110.7L126 T127 G130 G133 S134 D156 S165 K166 V167L126-R152 HydrophobicContact CB-CB 4.4Å; L126-R152 HydrophobicContact CD2-CB 4.25Å; L126-R152 WeakPolarHBondContact O-CD 3.45Å; L126-R152 PolarHBondContact O-NH1 2.79Å; T127-R152 VanDerWaalsContact C-NH1 3.34Å; T127-R152 PolarHBondContact O-NH1 3.42Å; G130-R152 PolarHBondContact O-NH1 3.38Å; G133-R152 WeakPolarHBondContact CA-O 3.23Å; G133-R152 PolarHBondContact N-O 3.23Å; S134-R152 PolarHBondContact O-N 3.14Å; R152-D156 IonicContact CZ-OD1 2.71Å; R152-D156 IonicContact NH2-OD1 3.59Å; R152-D156 PolarHBondContact NH2-OD1 3.38Å; R152-D156 IonicContact NH2-OD2 2.66Å; R152-S165 PolarHBondContact NE-OG 2.96Å; R152-K166 WeakPolarHBondContact CA-O 3.49Å; R152-V167 HydrophobicContact CB-CG2 4.48Å
153T89Confident72.2Confident5 Ų573.4 Ų73.43%0.03143%0.434CS..EExtended strand (participates in β ladder)trans-126.1156.1175.558.10000110.8V151 S165 K166 T208 L210V151-T153 HydrophobicContact CG1-CG2 4.32Å; T153-S165 CarbonylContact O-C 3.56Å; T153-S165 WeakPolarHBondContact O-CA 3.46Å; T153-K166 PolarHBondContact N-O 3.06Å; T153-K166 PolarHBondContact O-N 3.43Å; T153-K166 WeakPolarHBondContact OG1-CE 3.16Å; T153-K166 WeakPolarHBondContact OG1-CG 3.2Å; T153-T208 HydrophobicContact CG2-CG2 4.32Å; T153-L210 HydrophobicContact CG2-CD2 3.74Å
154G77.3Confident71.5Confident23 Ų2377.7 Ų77.724%0.23745%0.451CS..SBendtrans97.6152.8-171.300000113.8H132H132-G154 VanDerWaalsContact CB-O 3.32Å; H132-G154 WeakPolarHBondContact CB-O 3.44Å; H132-G154 PolarHBondContact ND1-N 3.13Å; H132-G154 PolarHBondContact ND1-O 3.17Å
155D61.9Low71.5Confident112 Ų11273.9 Ų73.960%0.59943%0.427SS*.  trans-99.4142.5-178.2-77.1-29.6000111.5H132 K157H132-D155 IonicContact CG-OD1 3.05Å; H132-D155 IonicContact ND1-OD1 3.11Å; D155-K157 PolarHBondContact O-N 3.39Å
156D56Low72.2Confident107 Ų10774.9 Ų74.957%0.57242%0.417SS*.SBendtrans-75-4.3176.8-62.4-38000113.1R152R152-D156 IonicContact CZ-OD1 2.71Å; R152-D156 IonicContact NH2-OD1 3.59Å; R152-D156 PolarHBondContact NH2-OD1 3.38Å; R152-D156 IonicContact NH2-OD2 2.66Å
157K50.7Low72.3Confident178 Ų17875 Ų7577%0.77442%0.418SS*.SBendtrans-95.8100.8177.2-66.1-172177.9-173.70108.8D155 E159D155-K157 PolarHBondContact O-N 3.39Å; K157-E159 VanDerWaalsContact C-N 3.26Å; K157-E159 PolarHBondContact O-N 3.36Å
158G48.6Very low72.4Confident82 Ų8274.7 Ų74.785%0.84542%0.419SS*.  trans-6770.6-17800000114.8
159E45.6Very low72.3Confident190 Ų19077.5 Ų77.589%0.88843%0.431SS*.  trans-114.89.7174.4-75.1-166.5162.200114.8K157K157-E159 VanDerWaalsContact C-N 3.26Å; K157-E159 PolarHBondContact O-N 3.36Å
160S44.2Very low72.3Confident91 Ų9178.5 Ų78.564%0.63644%0.437SS*.SBendtrans-137.1122.216957.60000111.1D162S160-D162 PolarHBondContact O-N 2.85Å
161N44.8Very low72.2Confident183 Ų18381.8 Ų81.898%0.97945%0.454SS*.THydrogen-bonded Turntrans-61.114-175.4-91.9-16.8000116.1
162D50.4Low72.2Confident165 Ų16581.8 Ų81.888%0.88245%0.454SS*.THydrogen-bonded Turntrans-145.411.2-173.5-138.510.4000116.4S160S160-D162 PolarHBondContact O-N 2.85Å
163G56.2Low72.2Confident44 Ų4485 Ų8545%0.45447%0.466SS..  trans-123.970-175.300000114.4S165G163-S165 PolarHBondContact O-N 3.01Å
164K66.2Low72.2Confident195 Ų19586.6 Ų86.685%0.84848%0.477SS*.  trans-60.3133.6169.4-76.2-177.1-179.5176.90109.7K166K164-K166 PolarHBondContact O-N 3.42Å; K164-K166 VanDerWaalsContact O-N 3.16Å
165S78.4Confident72.7Confident48 Ų4889.6 Ų89.634%0.33649%0.485SS..  trans-51.7122169.1171.10000109.1R152 T153 G163R152-S165 PolarHBondContact NE-OG 2.96Å; T153-S165 CarbonylContact O-C 3.56Å; T153-S165 WeakPolarHBondContact O-CA 3.46Å; G163-S165 PolarHBondContact O-N 3.01Å
166K89.2Confident73.8Confident74 Ų7492 Ų9232%0.32249%0.492SS..EExtended strand (participates in β ladder)trans-124.7151-178.870.7173.3178.8178.50110.7R152 T153 K164 E204 T208R152-K166 WeakPolarHBondContact CA-O 3.49Å; T153-K166 PolarHBondContact N-O 3.06Å; T153-K166 PolarHBondContact O-N 3.43Å; T153-K166 WeakPolarHBondContact OG1-CE 3.16Å; T153-K166 WeakPolarHBondContact OG1-CG 3.2Å; K164-K166 PolarHBondContact O-N 3.42Å; K164-K166 VanDerWaalsContact O-N 3.16Å; K166-E204 IonicContact NZ-OE1 3.88Å; K166-E204 IonicContact NZ-OE2 3.65Å; K166-E204 PolarHBondContact NZ-OE2 2.91Å; K166-T208 PolarHBondContact NZ-OG1 3.49Å
167V92.4Very high74.9Confident28 Ų2893.1 Ų93.117%0.1750%0.497CS..EExtended strand (participates in β ladder)trans-104121.8169.3176.20000107.9E123 L126 V151 R152E123-V167 HydrophobicContact CG-CB 4.06Å; E123-V167 HydrophobicContact CG-CG1 3.97Å; L126-V167 HydrophobicContact CB-CG2 3.85Å; L126-V167 HydrophobicContact CD1-CG1 3.66Å; L126-V167 HydrophobicContact CD1-CG2 4.29Å; V151-V167 CarbonylContact O-C 3.59Å; V151-V167 WeakPolarHBondContact O-CA 3.34Å; R152-V167 HydrophobicContact CB-CG2 4.48Å
168T93.6Very high76.7Confident20 Ų2088.1 Ų88.112%0.12348%0.476CS..EExtended strand (participates in β ladder)trans-99.8135.1174.7-61.10000109.1S150 V151 V170 E204 L210S150-T168 CarbonylContact C-O 3.56Å; S150-T168 WeakPolarHBondContact CA-O 3.38Å; V151-T168 PolarHBondContact N-O 3Å; V151-T168 PolarHBondContact O-N 2.88Å; T168-V170 HydrophobicContact CG2-CG2 4.27Å; T168-E204 WeakPolarHBondContact CB-OE1 3.29Å; T168-E204 WeakPolarHBondContact CG2-OE1 3.32Å; T168-E204 PolarHBondContact OG1-OE1 3.38Å; T168-L210 HydrophobicContact CG2-CD1 4.01Å; T168-L210 HydrophobicContact CG2-CD2 4.1Å
169H94.3Very high78.8Confident65 Ų6585.8 Ų85.830%0.30144%0.442SS..EExtended strand (participates in β ladder)trans-107.8120.6173.5-63.1-68000110.6E123 R138 V148 L149 S150E123-H169 WeakPolarHBondContact CG-NE2 3.22Å; E123-H169 IonicContact OE1-CD2 3.03Å; E123-H169 IonicContact OE1-NE2 2.72Å; E123-H169 PolarHBondContact OE1-NE2 3.18Å; R138-H169 PolarHBondContact NH2-ND1 2.99Å; V148-H169 HydrophobicContact CG1-CB 3.84Å; L149-H169 CarbonylContact O-C 3.48Å; L149-H169 WeakPolarHBondContact O-CA 3.22Å; S150-H169 WeakPolarHBondContact CB-ND1 3.14Å; S150-H169 PolarHBondContact OG-CE1 3.44Å; S150-H169 PolarHBondContact OG-ND1 2.76Å
170V94.9Very high81.2Confident21 Ų2177 Ų7713%0.12740%0.401CS..EExtended strand (participates in β ladder)trans-108.3122.8176.4-178.10000108.6V148 L149 T168 V181 M202 L210V148-V170 CarbonylContact C-O 3.46Å; V148-V170 WeakPolarHBondContact CA-O 3.31Å; L149-V170 HydrophobicContact CB-CB 4.3Å; L149-V170 PolarHBondContact N-O 3.4Å; L149-V170 PolarHBondContact O-N 2.94Å; T168-V170 HydrophobicContact CG2-CG2 4.27Å; V170-V181 HydrophobicContact CG1-CB 3.99Å; V170-V181 HydrophobicContact CG1-CG1 4.07Å; V170-M202 HydrophobicContact CB-CE 4.44Å; V170-M202 HydrophobicContact CG1-CE 4.22Å; V170-M202 HydrophobicContact CG1-SD 3.95Å; V170-M202 HydrophobicContact CG2-CE 4.06Å; V170-M202 HydrophobicContact CG2-SD 4.43Å; V170-L210 HydrophobicContact CG2-CD1 3.66Å
171M94.5Very high83.5Confident70 Ų7074.2 Ų74.235%0.34538%0.38SS..EExtended strand (participates in β ladder)trans-71.3134.1176.7-170.161.864.700110D146 F147 V148 R173 V181D146-M171 HydrophobicContact CB-SD 4.29Å; F147-M171 VanDerWaalsContact O-SD 3.39Å; V148-M171 HydrophobicContact CG2-CE 4.08Å; V148-M171 HydrophobicContact CG2-SD 3.96Å; M171-R173 HydrophobicContact CG-CG 4.41Å; M171-V181 WeakPolarHBondContact O-CA 3.47Å
172I95.7Very high85.5Confident0 Ų067.8 Ų67.80%036%0.357CS..EExtended strand (participates in β ladder)trans-113.9112.5171.9-62162.9000107.4V137 D146 F147 L149 Y179 D180 V181 L190 L193V137-I172 HydrophobicContact CG1-CD1 4.09Å; V137-I172 HydrophobicContact CG2-CD1 4.47Å; D146-I172 WeakPolarHBondContact CB-O 3.37Å; F147-I172 HydrophobicContact CB-CB 4Å; F147-I172 HydrophobicContact CB-CD1 4.34Å; F147-I172 HydrophobicContact CB-CG2 4.38Å; F147-I172 PolarHBondContact N-O 3.27Å; F147-I172 WeakPolarHBondContact O-CA 3.45Å; F147-I172 PolarHBondContact O-N 2.53Å; F147-I172 VanDerWaalsContact O-O 3.14Å; L149-I172 HydrophobicContact CB-CD1 3.78Å; L149-I172 HydrophobicContact CB-CG1 4.37Å; I172-Y179 HydrophobicContact CG2-CD1 4.29Å; I172-D180 CarbonylContact C-O 3.6Å; I172-D180 VanDerWaalsContact CA-O 3.3Å; I172-D180 WeakPolarHBondContact CA-O 3.23Å; I172-V181 HydrophobicContact CG1-CG1 4.07Å; I172-L190 HydrophobicContact CD1-CD2 4.28Å; I172-L190 HydrophobicContact CG2-CD2 3.71Å; I172-L193 HydrophobicContact CD1-CD2 4.08Å; I172-L193 HydrophobicContact CG1-CD1 4.4Å; I172-L193 HydrophobicContact CG1-CD2 4.34Å; I172-L193 HydrophobicContact CG2-CD1 3.73Å
173R92.6Very high87Confident85 Ų8562 Ų6232%0.32134%0.337SS..EExtended strand (participates in β ladder)trans-85.5140.4179.3-60.3-176.6-60.1-170.80.6110.3D146 M171 Y179 D180 G182D146-R173 WeakPolarHBondContact OD1-CA 3.36Å; M171-R173 HydrophobicContact CG-CG 4.41Å; R173-Y179 VanDerWaalsContact O-CA 3.32Å; R173-Y179 WeakPolarHBondContact O-CA 3.12Å; R173-D180 IonicContact CZ-OD1 3Å; R173-D180 VanDerWaalsContact CZ-OD1 3.3Å; R173-D180 PolarHBondContact N-O 2.99Å; R173-D180 IonicContact NE-OD1 3.97Å; R173-D180 PolarHBondContact NE-OD1 3.17Å; R173-D180 IonicContact NE-OD2 2.79Å; R173-D180 IonicContact NH2-OD1 3.81Å; R173-D180 PolarHBondContact NH2-OD1 3.03Å; R173-D180 IonicContact NH2-OD2 3.4Å; R173-D180 PolarHBondContact O-N 3.05Å; R173-D180 VanDerWaalsContact O-N 3.1Å; R173-G182 PolarHBondContact NH2-O 3.18Å
174C89.4Confident88.5Confident38 Ų3863.6 Ų63.626%0.25735%0.353SS..EExtended strand (participates in β ladder)trans-107.6108.6171-173.90000109.4G145 D146 K178 Y179G145-C174 WeakPolarHBondContact O-CB 3.25Å; D146-C174 PolarHBondContact OD1-N 3.04Å; C174-K178 CarbonylContact C-O 3.6Å; C174-K178 WeakPolarHBondContact CA-O 3.47Å; C174-Y179 HydrophobicContact CB-CD1 4.25Å; C174-Y179 HydrophobicContact CB-CE1 4.15Å
175Q86.2Confident89.7Confident86 Ų8659.7 Ų59.740%0.40234%0.337SS..EExtended strand (participates in β ladder)trans-127.5125.4179.9-61.7-179.87.500109.2L177 K178 R186Q175-L177 PolarHBondContact O-N 2.9Å; Q175-K178 PolarHBondContact N-O 3.1Å; Q175-K178 PolarHBondContact O-N 2.88Å; Q175-R186 PolarHBondContact O-NH2 3.04Å
176E85.5Confident90.4Very high161 Ų16162.2 Ų62.275%0.75234%0.34SS*.THydrogen-bonded Turntrans51.639.5-178.3-48.5171.414200113.2K178 R186E176-K178 PolarHBondContact O-N 3.05Å; E176-R186 IonicContact OE2-CZ 3.8Å; E176-R186 IonicContact OE2-NH1 3.76Å; E176-R186 PolarHBondContact OE2-NH1 3.3Å; E176-R186 IonicContact OE2-NH2 2.72Å; E176-R186 PolarHBondContact OE2-NH2 3Å
177L79.7Confident90.5Very high131 Ų13159.5 Ų59.569%0.68633%0.328SS*.THydrogen-bonded Turntrans62.121.7-175.9-54.8171.2000114.6Q175Q175-L177 PolarHBondContact O-N 2.9Å
178K89Confident90.3Very high74 Ų7463.1 Ų63.132%0.32235%0.346SS..EExtended strand (participates in β ladder)trans-118.2155.4169.5-63.1-165.5179.6-126.50111.1C174 Q175 E176 R186 F187 D188C174-K178 CarbonylContact C-O 3.6Å; C174-K178 WeakPolarHBondContact CA-O 3.47Å; Q175-K178 PolarHBondContact N-O 3.1Å; Q175-K178 PolarHBondContact O-N 2.88Å; E176-K178 PolarHBondContact O-N 3.05Å; K178-R186 HydrophobicContact CB-CB 4.27Å; K178-R186 HydrophobicContact CD-CB 4.14Å; K178-F187 CarbonylContact C-O 3.58Å; K178-F187 VanDerWaalsContact CA-O 3.22Å; K178-F187 WeakPolarHBondContact CA-O 3.37Å; K178-F187 WeakPolarHBondContact CB-O 3.44Å; K178-D188 WeakPolarHBondContact CE-OD1 3.44Å; K178-D188 IonicContact NZ-OD1 3.62Å; K178-D188 PolarHBondContact NZ-OD1 3.41Å
179Y92.6Very high90Very high32 Ų3262.3 Ų62.313%0.12534%0.342CS..EExtended strand (participates in β ladder)trans-114.4136.3-172.8-53.7-85.7000111.5F147 I172 R173 C174 F187 S189 L190F147-Y179 HydrophobicContact CD2-CD1 4.32Å; F147-Y179 HydrophobicContact CD2-CE1 4.05Å; F147-Y179 HydrophobicContact CE2-CD1 4.44Å; F147-Y179 AromaticContact CE2-CE1 3.74Å; F147-Y179 HydrophobicContact CE2-CE1 3.74Å; I172-Y179 HydrophobicContact CG2-CD1 4.29Å; R173-Y179 VanDerWaalsContact O-CA 3.32Å; R173-Y179 WeakPolarHBondContact O-CA 3.12Å; C174-Y179 HydrophobicContact CB-CD1 4.25Å; C174-Y179 HydrophobicContact CB-CE1 4.15Å; Y179-F187 PolarHBondContact N-O 2.84Å; Y179-F187 WeakPolarHBondContact O-CD2 3.26Å; Y179-F187 PolarHBondContact O-N 2.91Å; Y179-S189 VanDerWaalsContact CD2-C 3.46Å; Y179-L190 HydrophobicContact CD1-CD2 3.42Å; Y179-L190 VanDerWaalsContact CD1-CD2 3.42Å; Y179-L190 HydrophobicContact CD1-CG 3.91Å; Y179-L190 HydrophobicContact CE1-CD2 3.86Å; Y179-L190 HydrophobicContact CE1-CG 3.86Å; Y179-L190 HydrophobicContact CG-CD2 3.83Å; Y179-L190 HydrophobicContact CG-CG 4.28Å
180D94.4Very high89.7Confident6 Ų659.2 Ų59.23%0.03233%0.327CS..EExtended strand (participates in β ladder)trans-14816517474.286.3000111.5I172 R173 G182 R186I172-D180 CarbonylContact C-O 3.6Å; I172-D180 VanDerWaalsContact CA-O 3.3Å; I172-D180 WeakPolarHBondContact CA-O 3.23Å; R173-D180 IonicContact CZ-OD1 3Å; R173-D180 VanDerWaalsContact CZ-OD1 3.3Å; R173-D180 PolarHBondContact N-O 2.99Å; R173-D180 IonicContact NE-OD1 3.97Å; R173-D180 PolarHBondContact NE-OD1 3.17Å; R173-D180 IonicContact NE-OD2 2.79Å; R173-D180 IonicContact NH2-OD1 3.81Å; R173-D180 PolarHBondContact NH2-OD1 3.03Å; R173-D180 IonicContact NH2-OD2 3.4Å; R173-D180 PolarHBondContact O-N 3.05Å; R173-D180 VanDerWaalsContact O-N 3.1Å; D180-G182 PolarHBondContact OD1-N 2.65Å; D180-R186 HydrophobicContact CB-CG 4.31Å
181V93.5Very high89.3Confident33 Ų3358.9 Ų58.920%0.233%0.325CS..SBendtrans-106.222.5-177.5-62.40000114V170 M171 I172 L193 Y197 M202V170-V181 HydrophobicContact CG1-CB 3.99Å; V170-V181 HydrophobicContact CG1-CG1 4.07Å; M171-V181 WeakPolarHBondContact O-CA 3.47Å; I172-V181 HydrophobicContact CG1-CG1 4.07Å; V181-L193 HydrophobicContact CG1-CD1 4.19Å; V181-L193 HydrophobicContact CG1-CD2 4.31Å; V181-Y197 HydrophobicContact CG1-CE2 3.89Å; V181-Y197 HydrophobicContact CG2-CE2 4Å; V181-Y197 WeakPolarHBondContact CG2-OH 3.47Å; V181-M202 HydrophobicContact CG1-SD 4.45Å; V181-M202 HydrophobicContact CG2-SD 4.22Å
182G85.7Confident89.1Confident47 Ų4758 Ų5849%0.48532%0.322SS..SBendtrans114-22-176.200000114.2R173 D180R173-G182 PolarHBondContact NH2-O 3.18Å; D180-G182 PolarHBondContact OD1-N 2.65Å
183G82.6Confident89.1Confident45 Ų4558 Ų5846%0.46432%0.322SS..SBendtrans-178.4170.4179.200000112
184G87.6Confident89Confident77 Ų7754 Ų5479%0.79431%0.307SS*.SBendtrans89.7-140.9-177.200000113.4
185E90.8Very high89Confident112 Ų11255.7 Ų55.752%0.52331%0.311SS..  trans-73.6148.3-178.8-62.3-169.1144.900112.1F187 H196E185-F187 HydrophobicContact CB-CE1 4.22Å; E185-F187 HydrophobicContact CB-CE2 4.1Å; E185-F187 HydrophobicContact CB-CZ 3.73Å; E185-F187 WeakPolarHBondContact O-CE2 3.38Å; E185-H196 IonicContact OE2-CE1 3.73Å; E185-H196 PolarHBondContact OE2-CE1 2.86Å; E185-H196 IonicContact OE2-ND1 2.68Å; E185-H196 PolarHBondContact OE2-ND1 2.96Å; E185-H196 VanDerWaalsContact OE2-ND1 3.11Å
186R93.6Very high89.4Confident101 Ų10153.9 Ų53.938%0.38130%0.302SS..  trans-104.3131.8170.2-68177.371.4-1651.6108.9Q175 E176 K178 D180Q175-R186 PolarHBondContact O-NH2 3.04Å; E176-R186 IonicContact OE2-CZ 3.8Å; E176-R186 IonicContact OE2-NH1 3.76Å; E176-R186 PolarHBondContact OE2-NH1 3.3Å; E176-R186 IonicContact OE2-NH2 2.72Å; E176-R186 PolarHBondContact OE2-NH2 3Å; K178-R186 HydrophobicContact CB-CB 4.27Å; K178-R186 HydrophobicContact CD-CB 4.14Å; D180-R186 HydrophobicContact CB-CG 4.31Å
187F92.4Very high89.8Confident18 Ų1847.3 Ų47.38%0.07927%0.271CS..BIsolated β-bridgetrans-108.6148.1-174.8-58.1-81.4000111.8K178 Y179 E185 S189 D192 L193 H196 Y197K178-F187 CarbonylContact C-O 3.58Å; K178-F187 VanDerWaalsContact CA-O 3.22Å; K178-F187 WeakPolarHBondContact CA-O 3.37Å; K178-F187 WeakPolarHBondContact CB-O 3.44Å; Y179-F187 PolarHBondContact N-O 2.84Å; Y179-F187 WeakPolarHBondContact O-CD2 3.26Å; Y179-F187 PolarHBondContact O-N 2.91Å; E185-F187 HydrophobicContact CB-CE1 4.22Å; E185-F187 HydrophobicContact CB-CE2 4.1Å; E185-F187 HydrophobicContact CB-CZ 3.73Å; E185-F187 WeakPolarHBondContact O-CE2 3.38Å; F187-S189 VanDerWaalsContact C-N 3.33Å; F187-D192 HydrophobicContact CB-CB 4.3Å; F187-D192 HydrophobicContact CD1-CB 4.29Å; F187-L193 HydrophobicContact CB-CB 3.98Å; F187-L193 HydrophobicContact CD2-CB 3.65Å; F187-L193 HydrophobicContact CD2-CD1 3.9Å; F187-L193 HydrophobicContact CD2-CG 3.74Å; F187-L193 HydrophobicContact CE2-CB 4.32Å; F187-L193 HydrophobicContact CE2-CD1 4.5Å; F187-L193 HydrophobicContact CE2-CG 4.11Å; F187-L193 HydrophobicContact CG-CB 3.81Å; F187-L193 HydrophobicContact CG-CG 4.42Å; F187-H196 HydrophobicContact CD1-CB 4.44Å; F187-H196 HydrophobicContact CE1-CB 3.51Å; F187-H196 AromaticContact CE1-CG 3.61Å; F187-H196 AromaticContact CE1-ND1 3.68Å; F187-H196 HydrophobicContact CZ-CB 3.68Å; F187-H196 AromaticContact CZ-CD2 3.83Å; F187-H196 AromaticContact CZ-CG 3.46Å; F187-H196 VanDerWaalsContact CZ-CG 3.46Å; F187-H196 AromaticContact CZ-ND1 3.72Å; F187-Y197 AromaticContact CE2-CE2 3.92Å; F187-Y197 HydrophobicContact CE2-CE2 3.92Å; F187-Y197 HydrophobicContact CZ-CE2 4.4Å
188D88.1Confident90.3Very high103 Ų10344.7 Ų44.755%0.55125%0.254SS*.SBendtrans-79.6-16.2-180-63-29.9000112.9K178K178-D188 WeakPolarHBondContact CE-OD1 3.44Å; K178-D188 IonicContact NZ-OD1 3.62Å; K178-D188 PolarHBondContact NZ-OD1 3.41Å
189S87.8Confident90.5Very high4 Ų448.9 Ų48.93%0.02827%0.272CS..SBendtrans-147.9157.6176.272.60000112.2Y179 F187 T191 D192 L193Y179-S189 VanDerWaalsContact CD2-C 3.46Å; F187-S189 VanDerWaalsContact C-N 3.33Å; S189-T191 PolarHBondContact O-N 3.08Å; S189-D192 PolarHBondContact O-N 2.94Å; S189-D192 PolarHBondContact OG-N 2.73Å; S189-D192 PolarHBondContact OG-OD2 2.81Å; S189-L193 PolarHBondContact O-N 3.38Å; S189-L193 VanDerWaalsContact O-N 3.13Å
190L87.2Confident90.5Very high0 Ų051.4 Ų51.40%029%0.288CS..Hα-helixtrans-60.3-33.2170.8-70.6-179.7000111.8P107 W112 F113 V137 F147 I172 Y179 L193 V194P107-L190 HydrophobicContact CB-CB 4.34Å; P107-L190 HydrophobicContact CB-CD1 4.13Å; P107-L190 HydrophobicContact CG-CD1 3.97Å; W112-L190 HydrophobicContact CH2-CB 3.86Å; W112-L190 HydrophobicContact CZ3-CB 4.37Å; F113-L190 HydrophobicContact CD2-CD1 4.35Å; F113-L190 HydrophobicContact CE2-CD1 4.05Å; V137-L190 HydrophobicContact CG1-CD1 4.32Å; F147-L190 HydrophobicContact CB-CD1 4.49Å; F147-L190 HydrophobicContact CB-CD2 4.39Å; F147-L190 HydrophobicContact CD1-CD1 3.76Å; F147-L190 HydrophobicContact CD2-CD1 3.97Å; F147-L190 HydrophobicContact CD2-CD2 4.08Å; F147-L190 HydrophobicContact CD2-CG 4.47Å; F147-L190 HydrophobicContact CE1-CD1 3.89Å; F147-L190 HydrophobicContact CE2-CD1 4.13Å; F147-L190 HydrophobicContact CG-CD1 3.79Å; F147-L190 HydrophobicContact CG-CD2 4.22Å; F147-L190 HydrophobicContact CZ-CD1 4.08Å; I172-L190 HydrophobicContact CD1-CD2 4.28Å; I172-L190 HydrophobicContact CG2-CD2 3.71Å; Y179-L190 HydrophobicContact CD1-CD2 3.42Å; Y179-L190 VanDerWaalsContact CD1-CD2 3.42Å; Y179-L190 HydrophobicContact CD1-CG 3.91Å; Y179-L190 HydrophobicContact CE1-CD2 3.86Å; Y179-L190 HydrophobicContact CE1-CG 3.86Å; Y179-L190 HydrophobicContact CG-CD2 3.83Å; Y179-L190 HydrophobicContact CG-CG 4.28Å; L190-L193 PolarHBondContact O-N 2.87Å; L190-V194 WeakPolarHBondContact O-CB 3.36Å; L190-V194 WeakPolarHBondContact O-CG2 3.47Å; L190-V194 PolarHBondContact O-N 3Å
191T86.9Confident90.4Very high13 Ų1353.4 Ų53.48%0.0830%0.301CS..Hα-helixtrans-64.2-43.4176.2-58.40000111.6E110 S189 L193 V194 E195E110-T191 WeakPolarHBondContact OE1-CG2 3.32Å; E110-T191 PolarHBondContact OE1-OG1 2.9Å; S189-T191 PolarHBondContact O-N 3.08Å; T191-L193 VanDerWaalsContact C-N 3.34Å; T191-V194 PolarHBondContact O-N 3.5Å; T191-E195 HydrophobicContact CG2-CG 4.45Å; T191-E195 WeakPolarHBondContact O-CB 3.45Å; T191-E195 WeakPolarHBondContact O-CG 3.37Å; T191-E195 PolarHBondContact O-N 2.8Å
192D89.9Confident90.3Very high52 Ų5253.1 Ų53.128%0.27830%0.298SS..Hα-helixtrans-65.4-40.2177.5-61.6-46000111.1R5 F187 S189 H196R5-D192 IonicContact CZ-OD1 3.44Å; R5-D192 IonicContact NH1-OD1 3.51Å; R5-D192 PolarHBondContact NH1-OD1 2.86Å; F187-D192 HydrophobicContact CB-CB 4.3Å; F187-D192 HydrophobicContact CD1-CB 4.29Å; S189-D192 PolarHBondContact O-N 2.94Å; S189-D192 PolarHBondContact OG-N 2.73Å; S189-D192 PolarHBondContact OG-OD2 2.81Å; D192-H196 WeakPolarHBondContact O-CB 2.77Å; D192-H196 PolarHBondContact O-N 2.91Å
193L94.4Very high90.5Very high0 Ų055.5 Ų55.50%030%0.303CS..Hα-helixtrans-59-50.5173.6-176.1154.5000111.4I172 V181 F187 S189 L190 T191 H196 Y197I172-L193 HydrophobicContact CD1-CD2 4.08Å; I172-L193 HydrophobicContact CG1-CD1 4.4Å; I172-L193 HydrophobicContact CG1-CD2 4.34Å; I172-L193 HydrophobicContact CG2-CD1 3.73Å; V181-L193 HydrophobicContact CG1-CD1 4.19Å; V181-L193 HydrophobicContact CG1-CD2 4.31Å; F187-L193 HydrophobicContact CB-CB 3.98Å; F187-L193 HydrophobicContact CD2-CB 3.65Å; F187-L193 HydrophobicContact CD2-CD1 3.9Å; F187-L193 HydrophobicContact CD2-CG 3.74Å; F187-L193 HydrophobicContact CE2-CB 4.32Å; F187-L193 HydrophobicContact CE2-CD1 4.5Å; F187-L193 HydrophobicContact CE2-CG 4.11Å; F187-L193 HydrophobicContact CG-CB 3.81Å; F187-L193 HydrophobicContact CG-CG 4.42Å; S189-L193 PolarHBondContact O-N 3.38Å; S189-L193 VanDerWaalsContact O-N 3.13Å; L190-L193 PolarHBondContact O-N 2.87Å; T191-L193 VanDerWaalsContact C-N 3.34Å; L193-H196 PolarHBondContact O-N 3.07Å; L193-Y197 HydrophobicContact CD2-CD2 3.76Å; L193-Y197 HydrophobicContact CD2-CE2 4.11Å; L193-Y197 HydrophobicContact CG-CD2 3.96Å; L193-Y197 HydrophobicContact CG-CE2 3.93Å; L193-Y197 WeakPolarHBondContact O-CD2 3.34Å; L193-Y197 PolarHBondContact O-N 3.14Å
194V91.9Very high90.5Very high0 Ų055.5 Ų55.50%029%0.291CS..Hα-helixtrans-64.9-43.7-179168.50000111.4W112 F135 V137 L190 T191 H196 Y197 K198W112-V194 HydrophobicContact CD2-CG1 4.3Å; W112-V194 HydrophobicContact CD2-CG2 4.26Å; W112-V194 HydrophobicContact CE3-CG2 4.1Å; W112-V194 HydrophobicContact CH2-CB 4.33Å; W112-V194 HydrophobicContact CH2-CG2 3.74Å; W112-V194 HydrophobicContact CZ2-CB 4.01Å; W112-V194 HydrophobicContact CZ2-CG1 4.26Å; W112-V194 HydrophobicContact CZ2-CG2 3.9Å; W112-V194 HydrophobicContact CZ3-CG2 3.85Å; F135-V194 HydrophobicContact CE2-CG1 3.7Å; F135-V194 HydrophobicContact CZ-CG1 3.96Å; V137-V194 HydrophobicContact CG2-CG2 4.06Å; L190-V194 WeakPolarHBondContact O-CB 3.36Å; L190-V194 WeakPolarHBondContact O-CG2 3.47Å; L190-V194 PolarHBondContact O-N 3Å; T191-V194 PolarHBondContact O-N 3.5Å; V194-H196 VanDerWaalsContact C-N 3.33Å; V194-H196 PolarHBondContact O-N 2.83Å; V194-Y197 PolarHBondContact O-N 3.41Å; V194-K198 HydrophobicContact CG1-CD 3.88Å; V194-K198 HydrophobicContact CG1-CG 4.31Å; V194-K198 WeakPolarHBondContact O-CB 3.19Å; V194-K198 VanDerWaalsContact O-CG 3.24Å; V194-K198 WeakPolarHBondContact O-CG 3.49Å; V194-K198 PolarHBondContact O-N 3Å
195E89.3Confident90.2Very high74 Ų7459.3 Ų59.335%0.34630%0.299SS..Hα-helixtrans-66.6-34.2178-73.7-62.1133.100112.6T191 K198 K199T191-E195 HydrophobicContact CG2-CG 4.45Å; T191-E195 WeakPolarHBondContact O-CB 3.45Å; T191-E195 WeakPolarHBondContact O-CG 3.37Å; T191-E195 PolarHBondContact O-N 2.8Å; E195-K198 WeakPolarHBondContact OE1-CD 3.33Å; E195-K198 IonicContact OE1-NZ 3.87Å; E195-K198 PolarHBondContact OE1-NZ 3.19Å; E195-K198 IonicContact OE2-NZ 2.95Å; E195-K199 PolarHBondContact O-N 3.14Å
196H93.8Very high89.7Confident49 Ų4961.6 Ų61.623%0.22731%0.314CS..Hα-helixtrans-60.5-54.5170.4179.5105.3000110.5E185 F187 D192 L193 V194 K198 K199 N200E185-H196 IonicContact OE2-CE1 3.73Å; E185-H196 PolarHBondContact OE2-CE1 2.86Å; E185-H196 IonicContact OE2-ND1 2.68Å; E185-H196 PolarHBondContact OE2-ND1 2.96Å; E185-H196 VanDerWaalsContact OE2-ND1 3.11Å; F187-H196 HydrophobicContact CD1-CB 4.44Å; F187-H196 HydrophobicContact CE1-CB 3.51Å; F187-H196 AromaticContact CE1-CG 3.61Å; F187-H196 AromaticContact CE1-ND1 3.68Å; F187-H196 HydrophobicContact CZ-CB 3.68Å; F187-H196 AromaticContact CZ-CD2 3.83Å; F187-H196 AromaticContact CZ-CG 3.46Å; F187-H196 VanDerWaalsContact CZ-CG 3.46Å; F187-H196 AromaticContact CZ-ND1 3.72Å; D192-H196 WeakPolarHBondContact O-CB 2.77Å; D192-H196 PolarHBondContact O-N 2.91Å; L193-H196 PolarHBondContact O-N 3.07Å; V194-H196 VanDerWaalsContact C-N 3.33Å; V194-H196 PolarHBondContact O-N 2.83Å; H196-K198 VanDerWaalsContact C-N 3.28Å; H196-K198 PolarHBondContact O-N 2.86Å; H196-K199 PolarHBondContact O-N 2.86Å; H196-N200 PolarHBondContact CE1-ND2 2.85Å; H196-N200 PolarHBondContact NE2-ND2 2.84Å; H196-N200 PolarHBondContact O-N 3.16Å; H196-N200 PolarHBondContact O-ND2 2.92Å
197Y94.4Very high89Confident23 Ų2359.1 Ų59.19%0.0932%0.32CS..Hα-helixtrans-74.2-14.5-176.5-71.1-63.1000114.5V181 F187 L193 V194 N200 P201 M202V181-Y197 HydrophobicContact CG1-CE2 3.89Å; V181-Y197 HydrophobicContact CG2-CE2 4Å; V181-Y197 WeakPolarHBondContact CG2-OH 3.47Å; F187-Y197 AromaticContact CE2-CE2 3.92Å; F187-Y197 HydrophobicContact CE2-CE2 3.92Å; F187-Y197 HydrophobicContact CZ-CE2 4.4Å; L193-Y197 HydrophobicContact CD2-CD2 3.76Å; L193-Y197 HydrophobicContact CD2-CE2 4.11Å; L193-Y197 HydrophobicContact CG-CD2 3.96Å; L193-Y197 HydrophobicContact CG-CE2 3.93Å; L193-Y197 WeakPolarHBondContact O-CD2 3.34Å; L193-Y197 PolarHBondContact O-N 3.14Å; V194-Y197 PolarHBondContact O-N 3.41Å; Y197-N200 WeakPolarHBondContact CA-O 3.48Å; Y197-N200 WeakPolarHBondContact CD1-O 3.43Å; Y197-N200 CarbonylContact O-C 3.58Å; Y197-P201 WeakPolarHBondContact O-CA 3.37Å; Y197-M202 HydrophobicContact CD1-CG 3.4Å; Y197-M202 HydrophobicContact CD1-SD 4.12Å; Y197-M202 HydrophobicContact CE1-CG 3.57Å; Y197-M202 HydrophobicContact CE1-SD 4.17Å; Y197-M202 HydrophobicContact CG-CE 4.35Å; Y197-M202 HydrophobicContact CG-CG 4.13Å; Y197-M202 HydrophobicContact CG-SD 4.39Å
198K91.3Very high88.7Confident76 Ų7660.3 Ų60.333%0.3333%0.328SS..Hα-helixtrans-68-36.9165.3-80.2171.769.9-169.30112.3F135 V194 E195 H196 L212F135-K198 HydrophobicContact CZ-CD 4.21Å; V194-K198 HydrophobicContact CG1-CD 3.88Å; V194-K198 HydrophobicContact CG1-CG 4.31Å; V194-K198 WeakPolarHBondContact O-CB 3.19Å; V194-K198 VanDerWaalsContact O-CG 3.24Å; V194-K198 WeakPolarHBondContact O-CG 3.49Å; V194-K198 PolarHBondContact O-N 3Å; E195-K198 WeakPolarHBondContact OE1-CD 3.33Å; E195-K198 IonicContact OE1-NZ 3.87Å; E195-K198 PolarHBondContact OE1-NZ 3.19Å; E195-K198 IonicContact OE2-NZ 2.95Å; H196-K198 VanDerWaalsContact C-N 3.28Å; H196-K198 PolarHBondContact O-N 2.86Å; K198-L212 HydrophobicContact CB-CB 4.43Å; K198-L212 HydrophobicContact CG-CB 3.51Å; K198-L212 HydrophobicContact CG-CD1 4.09Å; K198-L212 HydrophobicContact CG-CG 4.41Å
199K92Very high88.8Confident161 Ų16158.1 Ų58.170%0.732%0.319SS*.Hα-helixtrans-85.5-34.2178.1-67.4177.5-177.1175.30112.3E195 H196 P201E195-K199 PolarHBondContact O-N 3.14Å; H196-K199 PolarHBondContact O-N 2.86Å; K199-P201 WeakPolarHBondContact O-CD 3.46Å
200N92.8Very high88.9Confident85 Ų8558.1 Ų58.146%0.45532%0.318SS..SBendtrans-120.879.9-178.1-53.5-51.1000109.5H196 Y197 M202H196-N200 PolarHBondContact CE1-ND2 2.85Å; H196-N200 PolarHBondContact NE2-ND2 2.84Å; H196-N200 PolarHBondContact O-N 3.16Å; H196-N200 PolarHBondContact O-ND2 2.92Å; Y197-N200 WeakPolarHBondContact CA-O 3.48Å; Y197-N200 WeakPolarHBondContact CD1-O 3.43Å; Y197-N200 CarbonylContact O-C 3.58Å; N200-M202 PolarHBondContact O-N 2.89Å
201P92.3Very high89.1Confident48 Ų4861.5 Ų61.531%0.31233%0.334SS..  trans-59138.3-175.4-25.835.9000112.9Y197 K199 V209 Q211Y197-P201 WeakPolarHBondContact O-CA 3.37Å; K199-P201 WeakPolarHBondContact O-CD 3.46Å; P201-V209 HydrophobicContact CB-CG1 3.55Å; P201-V209 HydrophobicContact CG-CG1 4.37Å; P201-Q211 HydrophobicContact CB-CG 4.39Å; P201-Q211 HydrophobicContact CG-CG 4.39Å
202M92.3Very high89.4Confident28 Ų2861.3 Ų61.314%0.13833%0.332CS..EExtended strand (participates in β ladder)trans-68.1147.8172.6-64.8174.5-77.200110.5L149 V170 V181 Y197 N200 L210L149-M202 HydrophobicContact CD2-CE 3.57Å; V170-M202 HydrophobicContact CB-CE 4.44Å; V170-M202 HydrophobicContact CG1-CE 4.22Å; V170-M202 HydrophobicContact CG1-SD 3.95Å; V170-M202 HydrophobicContact CG2-CE 4.06Å; V170-M202 HydrophobicContact CG2-SD 4.43Å; V181-M202 HydrophobicContact CG1-SD 4.45Å; V181-M202 HydrophobicContact CG2-SD 4.22Å; Y197-M202 HydrophobicContact CD1-CG 3.4Å; Y197-M202 HydrophobicContact CD1-SD 4.12Å; Y197-M202 HydrophobicContact CE1-CG 3.57Å; Y197-M202 HydrophobicContact CE1-SD 4.17Å; Y197-M202 HydrophobicContact CG-CE 4.35Å; Y197-M202 HydrophobicContact CG-CG 4.13Å; Y197-M202 HydrophobicContact CG-SD 4.39Å; N200-M202 PolarHBondContact O-N 2.89Å; M202-L210 HydrophobicContact CB-CB 4.29Å; M202-L210 HydrophobicContact CB-CD1 4.19Å; M202-L210 HydrophobicContact CE-CD1 4.29Å; M202-L210 PolarHBondContact O-N 3.45Å
203V88.5Confident89.3Confident96 Ų9664.2 Ų64.258%0.58234%0.343SS*.EExtended strand (participates in β ladder)trans-121.2121.9177.9-1730000108.6T208 V209V203-T208 WeakPolarHBondContact CA-O 3.14Å; V203-V209 HydrophobicContact CG2-CG2 4.32Å
204E83.9Confident88.8Confident46 Ų4666.1 Ų66.122%0.21535%0.352CS..  trans-67.7157.1173.4-69.9-177.6177.600110.8K166 T168 L206 G207 T208 L210K166-E204 IonicContact NZ-OE1 3.88Å; K166-E204 IonicContact NZ-OE2 3.65Å; K166-E204 PolarHBondContact NZ-OE2 2.91Å; T168-E204 WeakPolarHBondContact CB-OE1 3.29Å; T168-E204 WeakPolarHBondContact CG2-OE1 3.32Å; T168-E204 PolarHBondContact OG1-OE1 3.38Å; E204-L206 PolarHBondContact O-N 3.26Å; E204-L206 VanDerWaalsContact O-N 3.07Å; E204-G207 WeakPolarHBondContact O-CA 3.47Å; E204-G207 PolarHBondContact O-N 3.37Å; E204-T208 PolarHBondContact N-O 2.7Å; E204-L210 HydrophobicContact CG-CD1 4.45Å; E204-L210 HydrophobicContact CG-CD2 4.39Å; E204-L210 HydrophobicContact CG-CG 4.41Å
205T81Confident88.6Confident156 Ų15667.8 Ų67.896%0.95736%0.363SS*.THydrogen-bonded Turntrans-55.1-30.4178.4-420000113.3G207T205-G207 PolarHBondContact O-N 2.95Å
206L79.3Confident88.2Confident160 Ų16064.3 Ų64.384%0.83835%0.346SS*.THydrogen-bonded Turntrans-83.27.3176.6-63.3172.6000113.3E204E204-L206 PolarHBondContact O-N 3.26Å; E204-L206 VanDerWaalsContact O-N 3.07Å
207G80.8Confident87Confident49 Ų4963.4 Ų63.451%0.50534%0.343SS..SBendtrans85.71.6176.800000115.7E204 T205 V209E204-G207 WeakPolarHBondContact O-CA 3.47Å; E204-G207 PolarHBondContact O-N 3.37Å; T205-G207 PolarHBondContact O-N 2.95Å; G207-V209 PolarHBondContact O-N 3.15Å
208T85.7Confident86Confident43 Ų4364.6 Ų64.626%0.26435%0.353SS..  trans-69124.5176.3-56.20000110.3T153 K166 V203 E204T153-T208 HydrophobicContact CG2-CG2 4.32Å; K166-T208 PolarHBondContact NZ-OG1 3.49Å; V203-T208 WeakPolarHBondContact CA-O 3.14Å; E204-T208 PolarHBondContact N-O 2.7Å
209V89.1Confident85.6Confident58 Ų5861.7 Ų61.735%0.35234%0.341SS..EExtended strand (participates in β ladder)trans-88.9120176.8-171.90000110.4P201 V203 G207 Q211P201-V209 HydrophobicContact CB-CG1 3.55Å; P201-V209 HydrophobicContact CG-CG1 4.37Å; V203-V209 HydrophobicContact CG2-CG2 4.32Å; G207-V209 PolarHBondContact O-N 3.15Å; V209-Q211 HydrophobicContact CB-CG 4.37Å; V209-Q211 HydrophobicContact CG1-CG 3.73Å; V209-Q211 PolarHBondContact O-N 2.79Å; V209-Q211 VanDerWaalsContact O-N 3.1Å
210L91Very high85.1Confident4 Ų458.8 Ų58.82%0.02133%0.326CS..EExtended strand (participates in β ladder)trans-83.978.6177.4-57.5-176.8000110.3T153 T168 V170 M202 E204 L212T153-L210 HydrophobicContact CG2-CD2 3.74Å; T168-L210 HydrophobicContact CG2-CD1 4.01Å; T168-L210 HydrophobicContact CG2-CD2 4.1Å; V170-L210 HydrophobicContact CG2-CD1 3.66Å; M202-L210 HydrophobicContact CB-CB 4.29Å; M202-L210 HydrophobicContact CB-CD1 4.19Å; M202-L210 HydrophobicContact CE-CD1 4.29Å; M202-L210 PolarHBondContact O-N 3.45Å; E204-L210 HydrophobicContact CG-CD1 4.45Å; E204-L210 HydrophobicContact CG-CD2 4.39Å; E204-L210 HydrophobicContact CG-CG 4.41Å; L210-L212 PolarHBondContact O-N 3.45Å
211Q91.1Very high84.6Confident71 Ų7155.3 Ų55.333%0.33231%0.307SS..  trans-78.1118.2179.8-62.8-173.9-4.200111.7G133 P201 V209 K213G133-Q211 WeakPolarHBondContact CA-O 3.25Å; P201-Q211 HydrophobicContact CB-CG 4.39Å; P201-Q211 HydrophobicContact CG-CG 4.39Å; V209-Q211 HydrophobicContact CB-CG 4.37Å; V209-Q211 HydrophobicContact CG1-CG 3.73Å; V209-Q211 PolarHBondContact O-N 2.79Å; V209-Q211 VanDerWaalsContact O-N 3.1Å; Q211-K213 VanDerWaalsContact C-N 3.33Å; Q211-K213 HydrophobicContact CB-CG 4.13Å; Q211-K213 PolarHBondContact O-N 3.35Å; Q211-K213 VanDerWaalsContact O-N 3.07Å
212L92.4Very high84.1Confident8 Ų854.9 Ų54.94%0.04230%0.303CS..  trans-84.572.3175.7-54.3-173.1000110.7F135 L149 V151 K198 L210F135-L212 HydrophobicContact CB-CD2 3.82Å; F135-L212 HydrophobicContact CD1-CB 3.76Å; F135-L212 HydrophobicContact CD1-CD2 4.15Å; F135-L212 HydrophobicContact CD1-CG 4.49Å; F135-L212 HydrophobicContact CD2-CD2 4.32Å; F135-L212 HydrophobicContact CE1-CB 3.81Å; F135-L212 HydrophobicContact CG-CB 4.26Å; F135-L212 HydrophobicContact CG-CD2 3.85Å; F135-L212 HydrophobicContact CZ-CB 4.34Å; L149-L212 HydrophobicContact CD1-CD2 4.14Å; L149-L212 HydrophobicContact CD2-CD1 4.1Å; L149-L212 HydrophobicContact CD2-CD2 4.15Å; V151-L212 HydrophobicContact CB-CD2 4.47Å; V151-L212 HydrophobicContact CG1-CD2 4.04Å; V151-L212 HydrophobicContact CG2-CD2 3.53Å; K198-L212 HydrophobicContact CB-CB 4.43Å; K198-L212 HydrophobicContact CG-CB 3.51Å; K198-L212 HydrophobicContact CG-CD1 4.09Å; K198-L212 HydrophobicContact CG-CG 4.41Å; L210-L212 PolarHBondContact O-N 3.45Å
213K88.5Confident83.5Confident113 Ų11353.6 Ų53.649%0.49130%0.296SS..  trans-73.8-48.2-174.3-66.7-170.2-178.4-178.10112.9H132 G133 Q211H132-K213 PolarHBondContact CD2-NZ 3.45Å; H132-K213 VanDerWaalsContact CD2-NZ 3.26Å; H132-K213 PolarHBondContact NE2-NZ 3.48Å; G133-K213 PolarHBondContact O-N 3.38Å; Q211-K213 VanDerWaalsContact C-N 3.33Å; Q211-K213 HydrophobicContact CB-CG 4.13Å; Q211-K213 PolarHBondContact O-N 3.35Å; Q211-K213 VanDerWaalsContact O-N 3.07Å
214Q84.3Confident83.2Confident41 Ų4150.9 Ų50.919%0.19228%0.284CS..EExtended strand (participates in β ladder)trans-145.6142.9-179.162.2-79.2-34.800112.6H132 G133 S134 F135H132-Q214 PolarHBondContact O-NE2 2.66Å; G133-Q214 VanDerWaalsContact C-NE2 3.31Å; G133-Q214 PolarHBondContact O-N 2.91Å; G133-Q214 VanDerWaalsContact O-N 3.14Å; S134-Q214 CarbonylContact C-O 3.59Å; S134-Q214 VanDerWaalsContact CA-O 3.26Å; S134-Q214 WeakPolarHBondContact CA-O 3.39Å; S134-Q214 PolarHBondContact OG-NE2 2.89Å; F135-Q214 VanDerWaalsContact CD1-C 3.48Å; F135-Q214 WeakPolarHBondContact CD1-O 3.49Å; F135-Q214 PolarHBondContact N-O 2.89Å
215P86.2Confident83.2Confident35 Ų3554 Ų5423%0.22730%0.298CS..EExtended strand (participates in β ladder)trans-53.4145.9162.4-26.536.9000111R111 W112 F135 N217R111-P215 HydrophobicContact CB-CB 4.03Å; R111-P215 HydrophobicContact CB-CG 4.25Å; W112-P215 HydrophobicContact CB-CB 3.85Å; W112-P215 HydrophobicContact CB-CG 4.12Å; F135-P215 HydrophobicContact CE1-CG 4.35Å; F135-P215 HydrophobicContact CZ-CG 4.17Å; F135-P215 CarbonylContact O-C 3.57Å; F135-P215 WeakPolarHBondContact O-CA 3.33Å; P215-N217 PolarHBondContact O-N 3.1Å
216L82Confident83.6Confident1 Ų146.7 Ų46.71%0.00525%0.253CS..  trans-58.8131.9170.6-178.263.9000109.9L125 L126 K129 F135 L136 T218L125-L216 HydrophobicContact CB-CD2 3.72Å; L126-L216 HydrophobicContact CD2-CB 4.4Å; L126-L216 HydrophobicContact CD2-CD1 4.2Å; L126-L216 HydrophobicContact CD2-CD2 4.41Å; L126-L216 HydrophobicContact CG-CD2 4.43Å; K129-L216 HydrophobicContact CB-CD1 4Å; F135-L216 PolarHBondContact O-N 2.78Å; L136-L216 HydrophobicContact CB-CB 4.46Å; L136-L216 HydrophobicContact CD2-CB 4.44Å; L136-L216 HydrophobicContact CD2-CD2 3.64Å; L216-T218 PolarHBondContact O-N 3.2Å
217N68.8Low84Confident29 Ų2943.3 Ų43.316%0.15523%0.233CC..  trans-82.2110.8174.9-170-10000109.8P215 T219 R220 D493P215-N217 PolarHBondContact O-N 3.1Å; N217-T219 PolarHBondContact OD1-N 3.31Å; N217-T219 PolarHBondContact OD1-OG1 3.41Å; N217-T219 VanDerWaalsContact OD1-OG1 3.06Å; N217-R220 PolarHBondContact OD1-N 2.89Å; N217-D493 PolarHBondContact ND2-OD2 2.98Å
218T72.4Confident84.1Confident48 Ų4844.9 Ų44.929%0.29424%0.236SC..  trans-99.8-11.7175.347.50000114.3H114 L216H114-T218 WeakPolarHBondContact CE1-CG2 3.35Å; L216-T218 PolarHBondContact O-N 3.2Å
219T82.8Confident84.1Confident15 Ų1544 Ų449%0.09223%0.228CC..SBendtrans-93.1-18.9-171.761.90000113N217 E250 D493 P495N217-T219 PolarHBondContact OD1-N 3.31Å; N217-T219 PolarHBondContact OD1-OG1 3.41Å; N217-T219 VanDerWaalsContact OD1-OG1 3.06Å; T219-E250 HydrophobicContact CG2-CG 4.05Å; T219-E250 VanDerWaalsContact CG2-OE2 3.31Å; T219-E250 WeakPolarHBondContact CG2-OE2 3.25Å; T219-D493 PolarHBondContact OG1-OD1 2.99Å; T219-P495 HydrophobicContact CG2-CG 3.72Å
220R81.5Confident84.1Confident100 Ų10041.7 Ų41.738%0.37721%0.214SC..  trans-73.3126.1171.5-173178.166.6-147.3-3.3110.5N217 D491 I492 D493N217-R220 PolarHBondContact OD1-N 2.89Å; R220-D491 HydrophobicContact CG-CB 4.22Å; R220-D491 IonicContact NE-OD2 2.82Å; R220-I492 WeakPolarHBondContact CA-O 3.34Å; R220-D493 HydrophobicContact CB-CB 4.19Å; R220-D493 HydrophobicContact CG-CB 4.42Å
221I82.1Confident83.9Confident13 Ų1348.7 Ų48.77%0.06724%0.24CC..EExtended strand (participates in β ladder)trans-133.7159.3178.556.7163.1000110I226 R229 D491 I492I221-I226 HydrophobicContact CD1-CB 4.33Å; I221-I226 HydrophobicContact CD1-CD1 3.56Å; I221-R229 HydrophobicContact CD1-CB 3.79Å; I221-R229 HydrophobicContact CD1-CG 3.97Å; I221-R229 HydrophobicContact CG2-CB 4.4Å; I221-R229 HydrophobicContact CG2-CG 4.25Å; I221-D491 WeakPolarHBondContact O-CA 3.42Å; I221-I492 HydrophobicContact CD1-CD1 4.2Å; I221-I492 HydrophobicContact CD1-CG1 4.19Å; I221-I492 HydrophobicContact CG1-CD1 4.38Å; I221-I492 HydrophobicContact CG1-CG1 3.81Å; I221-I492 PolarHBondContact N-O 2.96Å; I221-I492 PolarHBondContact O-N 2.83Å
222N81.4Confident83.4Confident39 Ų3950.5 Ų50.521%0.20925%0.249CC..EExtended strand (participates in β ladder)trans-70.9141.3163.7-172.5-81.9000109.2A224 E225 V488 D489N222-A224 VanDerWaalsContact C-N 3.28Å; N222-A224 PolarHBondContact O-N 3.44Å; N222-A224 VanDerWaalsContact OD1-CB 3.29Å; N222-A224 WeakPolarHBondContact OD1-CB 3.34Å; N222-A224 PolarHBondContact OD1-N 3.22Å; N222-E225 HydrophobicContact CB-CB 4.5Å; N222-E225 HydrophobicContact CB-CG 4.11Å; N222-E225 WeakPolarHBondContact O-CB 3.45Å; N222-E225 PolarHBondContact O-N 2.88Å; N222-V488 PolarHBondContact OD1-O 3.13Å; N222-D489 VanDerWaalsContact ND2-C 3.29Å; N222-D489 PolarHBondContact ND2-O 2.93Å
223A81.7Confident83Confident0 Ų050.3 Ų50.30%025%0.248CC..G310 helixtrans-63.2-34.7-176.200000112E225 I226 I483 V488 C490 I492 I526A223-E225 PolarHBondContact O-N 2.71Å; A223-I226 VanDerWaalsContact O-CB 3.32Å; A223-I226 WeakPolarHBondContact O-CB 3.49Å; A223-I226 VanDerWaalsContact O-CG2 3.28Å; A223-I226 WeakPolarHBondContact O-CG2 3.26Å; A223-I226 PolarHBondContact O-N 3.12Å; A223-I226 VanDerWaalsContact O-N 3.13Å; A223-I483 HydrophobicContact CB-CD1 4.48Å; A223-I483 HydrophobicContact CB-CG1 4.14Å; A223-V488 WeakPolarHBondContact CB-O 3.38Å; A223-C490 WeakPolarHBondContact CB-O 3.35Å; A223-C490 PolarHBondContact N-O 3.36Å; A223-I492 HydrophobicContact CB-CD1 3.93Å; A223-I492 HydrophobicContact CB-CG1 4.14Å; A223-I492 HydrophobicContact CB-CG2 4.1Å; A223-I526 HydrophobicContact CB-CD1 3.64Å; A223-I526 WeakPolarHBondContact O-CD1 3.32Å
224A82.1Confident82.8Confident39 Ų3947.1 Ų47.132%0.32224%0.24SC..G310 helixtrans-62.8-21.3173.800000113.5N222 V488N222-A224 VanDerWaalsContact C-N 3.28Å; N222-A224 PolarHBondContact O-N 3.44Å; N222-A224 VanDerWaalsContact OD1-CB 3.29Å; N222-A224 WeakPolarHBondContact OD1-CB 3.34Å; N222-A224 PolarHBondContact OD1-N 3.22Å; A224-V488 PolarHBondContact N-O 2.91Å
225E83.1Confident82.4Confident112 Ų11252 Ų5252%0.52326%0.26SS..G310 helixtrans-90.54.2178.7-62.7179.6174.900113.4N222 A223 E227 S228 R229N222-E225 HydrophobicContact CB-CB 4.5Å; N222-E225 HydrophobicContact CB-CG 4.11Å; N222-E225 WeakPolarHBondContact O-CB 3.45Å; N222-E225 PolarHBondContact O-N 2.88Å; A223-E225 PolarHBondContact O-N 2.71Å; E225-E227 VanDerWaalsContact C-N 3.25Å; E225-E227 PolarHBondContact O-N 2.61Å; E225-S228 WeakPolarHBondContact O-CB 3.31Å; E225-S228 PolarHBondContact O-N 2.7Å; E225-S228 VanDerWaalsContact O-N 3.1Å; E225-R229 PolarHBondContact O-N 2.97Å
226I88.9Confident81Confident3 Ų357.5 Ų57.52%0.01529%0.287CS..Hα-helixtrans-56.1-38.3-176.3-169.265.3000112.6I221 A223 S228 R229 V230 I492 Y519 V522 Q523 I526I221-I226 HydrophobicContact CD1-CB 4.33Å; I221-I226 HydrophobicContact CD1-CD1 3.56Å; A223-I226 VanDerWaalsContact O-CB 3.32Å; A223-I226 WeakPolarHBondContact O-CB 3.49Å; A223-I226 VanDerWaalsContact O-CG2 3.28Å; A223-I226 WeakPolarHBondContact O-CG2 3.26Å; A223-I226 PolarHBondContact O-N 3.12Å; A223-I226 VanDerWaalsContact O-N 3.13Å; I226-S228 VanDerWaalsContact C-N 3.35Å; I226-S228 PolarHBondContact O-N 2.87Å; I226-R229 PolarHBondContact O-N 3.37Å; I226-V230 HydrophobicContact CG1-CG2 4.31Å; I226-V230 WeakPolarHBondContact O-CG2 3.18Å; I226-V230 PolarHBondContact O-N 3.25Å; I226-I492 HydrophobicContact CD1-CD1 4Å; I226-Y519 HydrophobicContact CD1-CD1 3.59Å; I226-Y519 HydrophobicContact CD1-CE1 4.01Å; I226-V522 HydrophobicContact CD1-CG1 4.44Å; I226-V522 HydrophobicContact CG1-CG1 4.23Å; I226-Q523 HydrophobicContact CG1-CB 4.15Å; I226-Q523 HydrophobicContact CG2-CB 4.12Å; I226-Q523 HydrophobicContact CG2-CG 4.29Å; I226-I526 HydrophobicContact CB-CD1 4.41Å; I226-I526 HydrophobicContact CG2-CB 4.36Å; I226-I526 HydrophobicContact CG2-CD1 3.87Å; I226-I526 HydrophobicContact CG2-CG2 4.48Å
227E88.8Confident79.5Confident89 Ų8959.5 Ų59.542%0.41630%0.304SS..Hα-helixtrans-63-44-180-166.5-154.3147.800110.9E225 R229 V230 R231E225-E227 VanDerWaalsContact C-N 3.25Å; E225-E227 PolarHBondContact O-N 2.61Å; E227-R229 VanDerWaalsContact C-N 3.34Å; E227-R229 PolarHBondContact O-N 2.77Å; E227-V230 PolarHBondContact O-N 2.79Å; E227-R231 WeakPolarHBondContact O-CB 3.37Å; E227-R231 PolarHBondContact O-N 2.95Å; E227-R231 IonicContact OE1-CZ 2.67Å; E227-R231 IonicContact OE1-NH2 3.17Å; E227-R231 PolarHBondContact OE1-NH2 3.05Å
228S82.3Confident78.1Confident81 Ų8167.2 Ų67.257%0.56634%0.339SS*.Hα-helixtrans-61.8-43.9175.8-173.50000110.8E225 I226 R231 E232E225-S228 WeakPolarHBondContact O-CB 3.31Å; E225-S228 PolarHBondContact O-N 2.7Å; E225-S228 VanDerWaalsContact O-N 3.1Å; I226-S228 VanDerWaalsContact C-N 3.35Å; I226-S228 PolarHBondContact O-N 2.87Å; S228-R231 WeakPolarHBondContact O-CB 3.45Å; S228-R231 PolarHBondContact O-N 2.88Å; S228-E232 WeakPolarHBondContact O-CB 3.31Å; S228-E232 PolarHBondContact O-N 3.27Å
229R85.9Confident76.5Confident26 Ų2670.9 Ų70.910%0.09836%0.361CS..Hα-helixtrans-64.5-42.9177.1-178.858.5177.5156.9-1.8112.4I221 E225 I226 E227 R231 E232 L233 E250 Y519I221-R229 HydrophobicContact CD1-CB 3.79Å; I221-R229 HydrophobicContact CD1-CG 3.97Å; I221-R229 HydrophobicContact CG2-CB 4.4Å; I221-R229 HydrophobicContact CG2-CG 4.25Å; E225-R229 PolarHBondContact O-N 2.97Å; I226-R229 PolarHBondContact O-N 3.37Å; E227-R229 VanDerWaalsContact C-N 3.34Å; E227-R229 PolarHBondContact O-N 2.77Å; R229-R231 VanDerWaalsContact C-N 3.3Å; R229-R231 PolarHBondContact O-N 3.26Å; R229-E232 WeakPolarHBondContact CD-OE2 3.49Å; R229-E232 IonicContact CZ-OE2 3.89Å; R229-E232 IonicContact NH1-OE1 3.44Å; R229-E232 PolarHBondContact NH1-OE1 3.43Å; R229-E232 IonicContact NH1-OE2 2.76Å; R229-E232 PolarHBondContact NH1-OE2 3.39Å; R229-E232 WeakPolarHBondContact O-CB 3.39Å; R229-E232 PolarHBondContact O-N 3.07Å; R229-L233 HydrophobicContact CG-CD1 3.96Å; R229-L233 HydrophobicContact CG-CG 4.39Å; R229-L233 VanDerWaalsContact CZ-CD2 3.47Å; R229-L233 WeakPolarHBondContact O-CB 3.46Å; R229-L233 WeakPolarHBondContact O-CG 3.47Å; R229-L233 PolarHBondContact O-N 2.87Å; R229-E250 IonicContact CZ-OE2 3.23Å; R229-E250 IonicContact NE-OE2 3.09Å; R229-E250 IonicContact NH2-OE2 2.81Å; R229-E250 PolarHBondContact NH2-OE2 2.65Å; R229-Y519 HydrophobicContact CG-CE1 4.09Å
230V88.4Confident74.4Confident8 Ų874.6 Ų74.65%0.04838%0.384CS..Hα-helixtrans-62.9-40.9176.2170.10000110.7I226 E227 L233 S234 F247 Y519 M520 Q523I226-V230 HydrophobicContact CG1-CG2 4.31Å; I226-V230 WeakPolarHBondContact O-CG2 3.18Å; I226-V230 PolarHBondContact O-N 3.25Å; E227-V230 PolarHBondContact O-N 2.79Å; V230-L233 PolarHBondContact O-N 3.15Å; V230-S234 VanDerWaalsContact O-CB 3.23Å; V230-S234 WeakPolarHBondContact O-CB 3.13Å; V230-S234 PolarHBondContact O-N 3.29Å; V230-S234 PolarHBondContact O-OG 3.09Å; V230-F247 HydrophobicContact CG1-CE2 4.5Å; V230-F247 HydrophobicContact CG1-CZ 4.19Å; V230-F247 HydrophobicContact CG2-CZ 4.36Å; V230-Y519 HydrophobicContact CG2-CD1 4.13Å; V230-M520 HydrophobicContact CG1-SD 3.8Å; V230-Q523 VanDerWaalsContact CG1-OE1 3.31Å; V230-Q523 HydrophobicContact CG2-CB 4.45Å
231R86.3Confident72.5Confident151 Ų15178 Ų7857%0.5741%0.41SS*.Hα-helixtrans-62.3-45.1175.3-166.5-176.6-58.8175.62.5111.2E227 S228 R229 S234 K235E227-R231 WeakPolarHBondContact O-CB 3.37Å; E227-R231 PolarHBondContact O-N 2.95Å; E227-R231 IonicContact OE1-CZ 2.67Å; E227-R231 IonicContact OE1-NH2 3.17Å; E227-R231 PolarHBondContact OE1-NH2 3.05Å; S228-R231 WeakPolarHBondContact O-CB 3.45Å; S228-R231 PolarHBondContact O-N 2.88Å; R229-R231 VanDerWaalsContact C-N 3.3Å; R229-R231 PolarHBondContact O-N 3.26Å; R231-S234 PolarHBondContact O-N 3.12Å; R231-K235 WeakPolarHBondContact O-CG 3.32Å; R231-K235 PolarHBondContact O-N 3.09Å
232E81.9Confident70.7Confident109 Ų10983.7 Ų83.751%0.50943%0.434SS..Hα-helixtrans-58.9-51.5175.2-172.2-163.8165.700111.7S228 R229 S234 K235S228-E232 WeakPolarHBondContact O-CB 3.31Å; S228-E232 PolarHBondContact O-N 3.27Å; R229-E232 WeakPolarHBondContact CD-OE2 3.49Å; R229-E232 IonicContact CZ-OE2 3.89Å; R229-E232 IonicContact NH1-OE1 3.44Å; R229-E232 PolarHBondContact NH1-OE1 3.43Å; R229-E232 IonicContact NH1-OE2 2.76Å; R229-E232 PolarHBondContact NH1-OE2 3.39Å; R229-E232 WeakPolarHBondContact O-CB 3.39Å; R229-E232 PolarHBondContact O-N 3.07Å; E232-S234 PolarHBondContact O-N 2.86Å; E232-K235 PolarHBondContact O-N 3.39Å
233L84.4Confident69Low5 Ų588.3 Ų88.33%0.02646%0.464CS..Hα-helixtrans-67.1-14.4178.4-71.5175.1000113.7R229 V230 G246 F247 E250 Y519R229-L233 HydrophobicContact CG-CD1 3.96Å; R229-L233 HydrophobicContact CG-CG 4.39Å; R229-L233 VanDerWaalsContact CZ-CD2 3.47Å; R229-L233 WeakPolarHBondContact O-CB 3.46Å; R229-L233 WeakPolarHBondContact O-CG 3.47Å; R229-L233 PolarHBondContact O-N 2.87Å; V230-L233 PolarHBondContact O-N 3.15Å; L233-G246 VanDerWaalsContact CD2-C 3.47Å; L233-G246 WeakPolarHBondContact O-CA 3.43Å; L233-F247 HydrophobicContact CB-CD1 4.08Å; L233-F247 HydrophobicContact CB-CD2 3.7Å; L233-F247 HydrophobicContact CB-CE1 3.94Å; L233-F247 HydrophobicContact CB-CE2 3.56Å; L233-F247 HydrophobicContact CB-CG 3.96Å; L233-F247 HydrophobicContact CB-CZ 3.69Å; L233-F247 HydrophobicContact CD1-CD1 3.85Å; L233-F247 HydrophobicContact CD1-CE1 3.54Å; L233-F247 HydrophobicContact CD1-CZ 4Å; L233-F247 HydrophobicContact CG-CE1 4.38Å; L233-F247 VanDerWaalsContact O-CD2 3.23Å; L233-F247 WeakPolarHBondContact O-CD2 3.4Å; L233-F247 PolarHBondContact O-N 3Å; L233-E250 HydrophobicContact CD2-CB 4.44Å; L233-Y519 HydrophobicContact CD1-CD1 4.28Å; L233-Y519 HydrophobicContact CD1-CE1 3.88Å; L233-Y519 HydrophobicContact CD1-CE2 4.34Å
234S83.3Confident67.7Low46 Ų4691.3 Ų91.332%0.32248%0.477SS..Hα-helixtrans-94.3-13.3176.5-630000113.7V230 R231 E232 L236 R516V230-S234 VanDerWaalsContact O-CB 3.23Å; V230-S234 WeakPolarHBondContact O-CB 3.13Å; V230-S234 PolarHBondContact O-N 3.29Å; V230-S234 PolarHBondContact O-OG 3.09Å; R231-S234 PolarHBondContact O-N 3.12Å; E232-S234 PolarHBondContact O-N 2.86Å; S234-L236 PolarHBondContact O-N 3.41Å; S234-R516 PolarHBondContact OG-NH2 2.9Å
235K75.8Confident67.2Low142 Ų14292.9 Ų92.962%0.61748%0.477SS*.  trans-65.4132.7-178.7-75.5176.4-174.8-179.40110.5R231 E232R231-K235 WeakPolarHBondContact O-CG 3.32Å; R231-K235 PolarHBondContact O-N 3.09Å; E232-K235 PolarHBondContact O-N 3.39Å
236L56.4Low67.1Low151 Ų15188.2 Ų88.279%0.79146%0.459SS*.  trans-75.9132.5163.8-70.2156.8000107.5S234 E238S234-L236 PolarHBondContact O-N 3.41Å; L236-E238 PolarHBondContact O-N 2.9Å; L236-E238 VanDerWaalsContact O-N 3.15Å
237A50.5Low67Low44 Ų4488.1 Ų88.136%0.36446%0.459SS..  trans-65.8115.516800000108.9T239A237-T239 PolarHBondContact O-N 3.4Å
238E40.4Very low66.9Low190 Ų19085.5 Ų85.589%0.88845%0.445SS*.THydrogen-bonded Turntrans-69.54.9-174-69.9180158.100114L236L236-E238 PolarHBondContact O-N 2.9Å; L236-E238 VanDerWaalsContact O-N 3.15Å
239T39.2Very low66.9Low125 Ų12584.6 Ų84.677%0.76743%0.432SS*.THydrogen-bonded Turntrans-137.35.4-163.449.90000118.9A237A237-T239 PolarHBondContact O-N 3.4Å
240T38.2Very low67Low94 Ų9484.1 Ų84.158%0.57743%0.431SS*.SBendtrans-150150.3168.636.30000113.1K242T240-K242 PolarHBondContact O-N 2.75Å
241D41.3Very low67.1Low172 Ų17283.9 Ų83.992%0.9243%0.429SS*.SBendtrans-56.721.5175.2-88.5-37.1000115.8
242K44.7Very low67.1Low132 Ų13277 Ų7757%0.57440%0.403SS*.  trans-98.393.9179.3-67-173.3179.8-178.90110.3T240 K244T240-K242 PolarHBondContact O-N 2.75Å; K242-K244 PolarHBondContact O-N 3.24Å
243V44.9Very low67.2Low136 Ų13673 Ų7382%0.82439%0.387SS*.  trans-65.521.1-169.7-179.60000116.4
244K54.2Low67.3Low62 Ų6273.2 Ų73.227%0.2739%0.388SS..  trans-152.698.7-173.3-60.9-176.1-176.5-179.20115.1K242 W248K242-K244 PolarHBondContact O-N 3.24Å; K244-W248 HydrophobicContact CB-CB 4.48Å; K244-W248 HydrophobicContact CB-CD2 3.92Å; K244-W248 HydrophobicContact CB-CE3 3.85Å; K244-W248 HydrophobicContact CB-CG 4.18Å; K244-W248 HydrophobicContact CB-CZ3 4.43Å; K244-W248 HydrophobicContact CD-CD2 3.77Å; K244-W248 HydrophobicContact CD-CE3 4.16Å; K244-W248 HydrophobicContact CD-CG 4.23Å; K244-W248 HydrophobicContact CD-CH2 4.19Å; K244-W248 HydrophobicContact CD-CZ2 3.86Å; K244-W248 HydrophobicContact CD-CZ3 4.36Å; K244-W248 HydrophobicContact CG-CD2 4.48Å
245Q72.1Confident67.4Low72 Ų7271.1 Ų71.134%0.33637%0.373SS..  trans-146159178.2-67.6-163-30.800117.5E249Q245-E249 HydrophobicContact CG-CG 4.43Å; Q245-E249 WeakPolarHBondContact CG-OE1 3.38Å; Q245-E249 PolarHBondContact NE2-OE1 3.39Å
246G81.4Confident67.6Low14 Ų1465.3 Ų65.314%0.14435%0.348CS..SBendtrans87.1-101.4-173.700000112.6L233 W248 E249 E250L233-G246 VanDerWaalsContact CD2-C 3.47Å; L233-G246 WeakPolarHBondContact O-CA 3.43Å; G246-W248 VanDerWaalsContact C-N 3.25Å; G246-W248 PolarHBondContact O-N 3.05Å; G246-E249 PolarHBondContact O-N 3.39Å; G246-E250 PolarHBondContact O-N 2.79Å; G246-E250 VanDerWaalsContact O-N 3.16Å
247F87.8Confident68.8Low2 Ų259.2 Ų59.21%0.00932%0.315CS..Hα-helixtrans-54.4-40.5-179.4-77.8-70.4000113.5V230 L233 F251 E512 Y515 R516 Y519V230-F247 HydrophobicContact CG1-CE2 4.5Å; V230-F247 HydrophobicContact CG1-CZ 4.19Å; V230-F247 HydrophobicContact CG2-CZ 4.36Å; L233-F247 HydrophobicContact CB-CD1 4.08Å; L233-F247 HydrophobicContact CB-CD2 3.7Å; L233-F247 HydrophobicContact CB-CE1 3.94Å; L233-F247 HydrophobicContact CB-CE2 3.56Å; L233-F247 HydrophobicContact CB-CG 3.96Å; L233-F247 HydrophobicContact CB-CZ 3.69Å; L233-F247 HydrophobicContact CD1-CD1 3.85Å; L233-F247 HydrophobicContact CD1-CE1 3.54Å; L233-F247 HydrophobicContact CD1-CZ 4Å; L233-F247 HydrophobicContact CG-CE1 4.38Å; L233-F247 VanDerWaalsContact O-CD2 3.23Å; L233-F247 WeakPolarHBondContact O-CD2 3.4Å; L233-F247 PolarHBondContact O-N 3Å; F247-F251 VanDerWaalsContact O-CB 3.27Å; F247-F251 WeakPolarHBondContact O-CB 3.28Å; F247-F251 PolarHBondContact O-N 3.23Å; F247-E512 HydrophobicContact CB-CG 4.46Å; F247-E512 WeakPolarHBondContact CB-OE1 3.25Å; F247-Y515 HydrophobicContact CD1-CD1 4.1Å; F247-Y515 HydrophobicContact CD1-CE1 4.23Å; F247-R516 HydrophobicContact CD1-CB 4.16Å; F247-R516 HydrophobicContact CD1-CG 4.29Å; F247-R516 HydrophobicContact CD2-CG 3.96Å; F247-R516 HydrophobicContact CE1-CB 4.45Å; F247-R516 HydrophobicContact CE1-CG 4.27Å; F247-R516 HydrophobicContact CE2-CG 3.94Å; F247-R516 HydrophobicContact CG-CB 4.2Å; F247-R516 HydrophobicContact CG-CG 4.13Å; F247-R516 HydrophobicContact CZ-CG 4.09Å; F247-Y519 HydrophobicContact CD1-CD2 4.16Å; F247-Y519 HydrophobicContact CE1-CD1 4.2Å; F247-Y519 AromaticContact CE1-CD2 3.56Å; F247-Y519 HydrophobicContact CE1-CD2 3.56Å; F247-Y519 HydrophobicContact CE1-CE2 4.16Å; F247-Y519 AromaticContact CE1-CG 3.57Å; F247-Y519 HydrophobicContact CE1-CG 3.57Å; F247-Y519 HydrophobicContact CZ-CG 4.27Å
248W86.4Confident70.3Confident33 Ų3357.6 Ų57.613%0.12530%0.3CS..Hα-helixtrans-65-44.5-178.5-176.480.4000112.4P9 P33 K244 G246 F251 E252 E512P9-W248 HydrophobicContact CB-CH2 3.64Å; P9-W248 HydrophobicContact CB-CZ2 4.49Å; P9-W248 HydrophobicContact CB-CZ3 4.39Å; P9-W248 WeakPolarHBondContact O-CH2 3.21Å; P33-W248 HydrophobicContact CG-CH2 4.47Å; P33-W248 HydrophobicContact CG-CZ2 3.75Å; K244-W248 HydrophobicContact CB-CB 4.48Å; K244-W248 HydrophobicContact CB-CD2 3.92Å; K244-W248 HydrophobicContact CB-CE3 3.85Å; K244-W248 HydrophobicContact CB-CG 4.18Å; K244-W248 HydrophobicContact CB-CZ3 4.43Å; K244-W248 HydrophobicContact CD-CD2 3.77Å; K244-W248 HydrophobicContact CD-CE3 4.16Å; K244-W248 HydrophobicContact CD-CG 4.23Å; K244-W248 HydrophobicContact CD-CH2 4.19Å; K244-W248 HydrophobicContact CD-CZ2 3.86Å; K244-W248 HydrophobicContact CD-CZ3 4.36Å; K244-W248 HydrophobicContact CG-CD2 4.48Å; G246-W248 VanDerWaalsContact C-N 3.25Å; G246-W248 PolarHBondContact O-N 3.05Å; W248-F251 PolarHBondContact O-N 3.33Å; W248-E252 HydrophobicContact CD2-CG 4.01Å; W248-E252 HydrophobicContact CE3-CG 4.39Å; W248-E252 HydrophobicContact CH2-CG 3.99Å; W248-E252 HydrophobicContact CZ2-CG 3.51Å; W248-E252 HydrophobicContact CZ3-CG 4.38Å; W248-E252 WeakPolarHBondContact O-CG 3.16Å; W248-E252 PolarHBondContact O-N 3.1Å; W248-E512 HydrophobicContact CB-CG 4.35Å
249E81.7Confident72.1Confident63 Ų6349 Ų4929%0.29426%0.261SS..Hα-helixtrans-67.1-41.8-179.8-67.2179.515300111.4Q245 G246 E252 T253Q245-E249 HydrophobicContact CG-CG 4.43Å; Q245-E249 WeakPolarHBondContact CG-OE1 3.38Å; Q245-E249 PolarHBondContact NE2-OE1 3.39Å; G246-E249 PolarHBondContact O-N 3.39Å; E249-E252 PolarHBondContact O-N 3.4Å; E249-T253 VanDerWaalsContact O-CB 3.32Å; E249-T253 WeakPolarHBondContact O-CB 3.14Å; E249-T253 PolarHBondContact O-N 3.25Å; E249-T253 PolarHBondContact O-OG1 3.39Å
250E87.2Confident74Confident16 Ų1649.8 Ų49.88%0.07525%0.254CS..Hα-helixtrans-64.8-42.1176.6-164.8-179.572.100111.3T219 R229 L233 G246 T253 L254 P495 Y515 Y519T219-E250 HydrophobicContact CG2-CG 4.05Å; T219-E250 VanDerWaalsContact CG2-OE2 3.31Å; T219-E250 WeakPolarHBondContact CG2-OE2 3.25Å; R229-E250 IonicContact CZ-OE2 3.23Å; R229-E250 IonicContact NE-OE2 3.09Å; R229-E250 IonicContact NH2-OE2 2.81Å; R229-E250 PolarHBondContact NH2-OE2 2.65Å; L233-E250 HydrophobicContact CD2-CB 4.44Å; G246-E250 PolarHBondContact O-N 2.79Å; G246-E250 VanDerWaalsContact O-N 3.16Å; E250-T253 WeakPolarHBondContact O-CB 3.49Å; E250-T253 PolarHBondContact O-N 3.19Å; E250-L254 PolarHBondContact O-N 3.42Å; E250-L254 VanDerWaalsContact O-N 3.09Å; E250-P495 HydrophobicContact CG-CG 4.31Å; E250-Y515 HydrophobicContact CB-CE1 4.34Å; E250-Y515 HydrophobicContact CG-CE1 4.4Å; E250-Y515 WeakPolarHBondContact CG-OH 3.38Å; E250-Y515 VanDerWaalsContact OE1-CE1 3.29Å; E250-Y515 WeakPolarHBondContact OE1-CE1 3.31Å; E250-Y515 VanDerWaalsContact OE1-CZ 3.27Å; E250-Y515 PolarHBondContact OE1-OH 2.94Å; E250-Y519 WeakPolarHBondContact OE1-CE2 3.38Å; E250-Y519 VanDerWaalsContact OE1-CZ 3.31Å; E250-Y519 PolarHBondContact OE1-OH 3.05Å; E250-Y519 PolarHBondContact OE2-OH 3Å
251F90.4Very high76.2Confident3 Ų346.2 Ų46.21%0.01323%0.231CC..Hα-helixtrans-63.6-46.8175.4-175.6-112.6000111.6F247 W248 T253 L254 Q255 E512 Y515F247-F251 VanDerWaalsContact O-CB 3.27Å; F247-F251 WeakPolarHBondContact O-CB 3.28Å; F247-F251 PolarHBondContact O-N 3.23Å; W248-F251 PolarHBondContact O-N 3.33Å; F251-T253 VanDerWaalsContact C-N 3.31Å; F251-T253 PolarHBondContact O-N 3.07Å; F251-L254 CarbonylContact O-C 3.58Å; F251-L254 WeakPolarHBondContact O-CA 3.38Å; F251-L254 VanDerWaalsContact O-CB 3.31Å; F251-L254 WeakPolarHBondContact O-CB 3.39Å; F251-L254 PolarHBondContact O-N 2.85Å; F251-L254 VanDerWaalsContact O-N 3.09Å; F251-Q255 HydrophobicContact CD1-CG 4.05Å; F251-Q255 HydrophobicContact CE1-CG 3.84Å; F251-Q255 HydrophobicContact CZ-CG 4.17Å; F251-Q255 WeakPolarHBondContact O-CG 3.09Å; F251-Q255 PolarHBondContact O-N 3.38Å; F251-E512 HydrophobicContact CB-CG 4.45Å; F251-E512 HydrophobicContact CD1-CB 3.82Å; F251-E512 HydrophobicContact CE1-CB 4.34Å; F251-E512 HydrophobicContact CG-CB 4.25Å; F251-Y515 HydrophobicContact CB-CD1 4.05Å; F251-Y515 HydrophobicContact CB-CE1 4.41Å; F251-Y515 HydrophobicContact CB-CG 4.14Å; F251-Y515 HydrophobicContact CD2-CD1 4.34Å; F251-Y515 AromaticContact CD2-CD2 3.54Å; F251-Y515 HydrophobicContact CD2-CD2 3.54Å; F251-Y515 HydrophobicContact CD2-CE2 4.25Å; F251-Y515 AromaticContact CD2-CG 3.58Å; F251-Y515 HydrophobicContact CD2-CG 3.58Å; F251-Y515 HydrophobicContact CE2-CD2 4.22Å; F251-Y515 HydrophobicContact CE2-CG 4.38Å; F251-Y515 HydrophobicContact CG-CD2 4.5Å; F251-Y515 HydrophobicContact CG-CG 4.21Å
252E86Confident78.3Confident5 Ų540.2 Ų40.22%0.02320%0.199CC..Hα-helixtrans-64.9-34.3177.7-73.1-57.8154.400112.8R4 F7 W248 E249 L254 Q255 Q256R4-E252 IonicContact NH1-OE2 3.27Å; R4-E252 PolarHBondContact NH1-OE2 2.97Å; F7-E252 WeakPolarHBondContact CE1-OE2 3.3Å; F7-E252 WeakPolarHBondContact CZ-OE2 3.38Å; W248-E252 HydrophobicContact CD2-CG 4.01Å; W248-E252 HydrophobicContact CE3-CG 4.39Å; W248-E252 HydrophobicContact CH2-CG 3.99Å; W248-E252 HydrophobicContact CZ2-CG 3.51Å; W248-E252 HydrophobicContact CZ3-CG 4.38Å; W248-E252 WeakPolarHBondContact O-CG 3.16Å; W248-E252 PolarHBondContact O-N 3.1Å; E249-E252 PolarHBondContact O-N 3.4Å; E252-L254 VanDerWaalsContact C-N 3.27Å; E252-L254 PolarHBondContact O-N 3.4Å; E252-Q255 WeakPolarHBondContact O-CB 3.42Å; E252-Q255 PolarHBondContact O-N 3.31Å; E252-Q255 VanDerWaalsContact O-N 3.12Å; E252-Q256 PolarHBondContact O-N 2.96Å
253T84.3Confident80.5Confident27 Ų2738.2 Ų38.217%0.16619%0.188CC..Hα-helixtrans-60.5-39.2172.2-61.90000111.4R111 E249 E250 F251R111-T253 HydrophobicContact CB-CG2 4.22Å; R111-T253 HydrophobicContact CG-CG2 3.29Å; E249-T253 VanDerWaalsContact O-CB 3.32Å; E249-T253 WeakPolarHBondContact O-CB 3.14Å; E249-T253 PolarHBondContact O-N 3.25Å; E249-T253 PolarHBondContact O-OG1 3.39Å; E250-T253 WeakPolarHBondContact O-CB 3.49Å; E250-T253 PolarHBondContact O-N 3.19Å; F251-T253 VanDerWaalsContact C-N 3.31Å; F251-T253 PolarHBondContact O-N 3.07Å
254L87.5Confident82.9Confident9 Ų934.7 Ų34.75%0.04717%0.17CC..Hα-helixtrans-67.4-42.9171.3172.566.5000111.5E250 F251 E252 Q256 Q257 P495 I498 Q499 Y515E250-L254 PolarHBondContact O-N 3.42Å; E250-L254 VanDerWaalsContact O-N 3.09Å; F251-L254 CarbonylContact O-C 3.58Å; F251-L254 WeakPolarHBondContact O-CA 3.38Å; F251-L254 VanDerWaalsContact O-CB 3.31Å; F251-L254 WeakPolarHBondContact O-CB 3.39Å; F251-L254 PolarHBondContact O-N 2.85Å; F251-L254 VanDerWaalsContact O-N 3.09Å; E252-L254 VanDerWaalsContact C-N 3.27Å; E252-L254 PolarHBondContact O-N 3.4Å; L254-Q256 PolarHBondContact O-N 3.15Å; L254-Q257 WeakPolarHBondContact O-CB 3.19Å; L254-Q257 PolarHBondContact O-N 3.38Å; L254-P495 HydrophobicContact CB-CB 4.34Å; L254-P495 HydrophobicContact CD1-CB 4.32Å; L254-P495 HydrophobicContact CD2-CB 4.21Å; L254-I498 HydrophobicContact CD2-CB 3.97Å; L254-I498 HydrophobicContact CD2-CD1 4.22Å; L254-I498 HydrophobicContact CD2-CG2 3.72Å; L254-Q499 HydrophobicContact CD1-CB 3.89Å; L254-Q499 VanDerWaalsContact CD1-OE1 3.29Å; L254-Y515 HydrophobicContact CD2-CD2 4.39Å; L254-Y515 HydrophobicContact CD2-CE2 3.98Å
255Q86Confident85Confident2 Ų233.2 Ų33.21%0.00916%0.162CC..Hα-helixtrans-58.6-35.9176.3-63.3-60.789.300112R4 Y63 F251 E252 Q257 E258R4-Q255 WeakPolarHBondContact CD-O 3.17Å; R4-Q255 VanDerWaalsContact NH1-CB 3.28Å; Y63-Q255 PolarHBondContact OH-NE2 2.91Å; F251-Q255 HydrophobicContact CD1-CG 4.05Å; F251-Q255 HydrophobicContact CE1-CG 3.84Å; F251-Q255 HydrophobicContact CZ-CG 4.17Å; F251-Q255 WeakPolarHBondContact O-CG 3.09Å; F251-Q255 PolarHBondContact O-N 3.38Å; E252-Q255 WeakPolarHBondContact O-CB 3.42Å; E252-Q255 PolarHBondContact O-N 3.31Å; E252-Q255 VanDerWaalsContact O-N 3.12Å; Q255-Q257 PolarHBondContact O-N 3.41Å; Q255-Q257 VanDerWaalsContact O-N 3.1Å; Q255-E258 WeakPolarHBondContact O-CB 3.38Å; Q255-E258 WeakPolarHBondContact O-CG 3.3Å; Q255-E258 PolarHBondContact O-N 2.9Å
256Q79.8Confident86.2Confident20 Ų2036.6 Ų36.69%0.09318%0.176CC..THydrogen-bonded Turntrans-59.3-23.6177.1-164.7650.500113.3E252 L254E252-Q256 PolarHBondContact O-N 2.96Å; L254-Q256 PolarHBondContact O-N 3.15Å
257Q81.8Confident87Confident22 Ų2238.2 Ų38.210%0.10318%0.18CC..THydrogen-bonded Turntrans-84.5-6.7179.3-50.9-54.1-61.100113.6L254 Q255 C259 K260L254-Q257 WeakPolarHBondContact O-CB 3.19Å; L254-Q257 PolarHBondContact O-N 3.38Å; Q255-Q257 PolarHBondContact O-N 3.41Å; Q255-Q257 VanDerWaalsContact O-N 3.1Å; Q257-C259 VanDerWaalsContact C-N 3.27Å; Q257-C259 PolarHBondContact O-N 3.42Å; Q257-K260 WeakPolarHBondContact O-CB 3.37Å; Q257-K260 PolarHBondContact O-N 3.44Å; Q257-K260 VanDerWaalsContact OE1-CE 3.28Å
258E81.8Confident87.5Confident10 Ų1038.2 Ų38.25%0.04718%0.18CC..G310 helixtrans-62.6-32.5-174.677-172.7-178.800112.9R4 T73 A75 Q255 K260 L261R4-E258 IonicContact CZ-OE1 3.8Å; R4-E258 IonicContact NE-OE1 2.95Å; R4-E258 PolarHBondContact NE-OE1 2.98Å; R4-E258 IonicContact NH2-OE1 2.62Å; R4-E258 PolarHBondContact NH2-OE1 2.89Å; T73-E258 WeakPolarHBondContact CB-OE2 3.32Å; A75-E258 HydrophobicContact CB-CG 3.63Å; A75-E258 WeakPolarHBondContact CB-OE1 3.13Å; A75-E258 PolarHBondContact N-OE1 3.47Å; Q255-E258 WeakPolarHBondContact O-CB 3.38Å; Q255-E258 WeakPolarHBondContact O-CG 3.3Å; Q255-E258 PolarHBondContact O-N 2.9Å; E258-K260 PolarHBondContact O-N 2.99Å; E258-L261 PolarHBondContact O-N 3.24Å
259C78.3Confident88Confident10 Ų1041.9 Ų41.97%0.06820%0.199CC..G310 helixtrans-64.6-19.6176.9-74.60000113.4Q257 L261Q257-C259 VanDerWaalsContact C-N 3.27Å; Q257-C259 PolarHBondContact O-N 3.42Å; C259-L261 PolarHBondContact O-N 3.47Å
260K77.8Confident88.7Confident142 Ų14243.3 Ų43.362%0.61720%0.201SC*.G310 helixtrans-76.8-13.4174.6-61.2-179.1176.8173.50112.7Q257 E258Q257-K260 WeakPolarHBondContact O-CB 3.37Å; Q257-K260 PolarHBondContact O-N 3.44Å; Q257-K260 VanDerWaalsContact OE1-CE 3.28Å; E258-K260 PolarHBondContact O-N 2.99Å
261L85.1Confident89.2Confident19 Ų1948.8 Ų48.810%0.09923%0.227CC..G310 helixtrans-114.525.4-174.9-55.1-177.9000112.3E258 C259 Y263 F285 R502E258-L261 PolarHBondContact O-N 3.24Å; C259-L261 PolarHBondContact O-N 3.47Å; L261-Y263 HydrophobicContact CB-CD2 4.41Å; L261-Y263 HydrophobicContact CB-CE2 4Å; L261-Y263 HydrophobicContact CD2-CE2 3.76Å; L261-Y263 VanDerWaalsContact CD2-OH 3.25Å; L261-Y263 WeakPolarHBondContact CD2-OH 3.25Å; L261-Y263 HydrophobicContact CG-CE2 4.45Å; L261-Y263 PolarHBondContact O-N 2.96Å; L261-F285 WeakPolarHBondContact O-CZ 3.33Å; L261-R502 HydrophobicContact CD1-CB 3.74Å
262L85.1Confident89.5Confident46 Ų4653 Ų5324%0.24125%0.247CC..  trans-75.968173.9-66.8175000110.6M1 A75 E76M1-L262 WeakPolarHBondContact O-CD1 3.47Å; A75-L262 HydrophobicContact CB-CD2 4.29Å; E76-L262 HydrophobicContact CG-CD2 4.08Å
263Y92.1Very high90.1Very high90 Ų9052.8 Ų52.835%0.35325%0.246SC..  trans-77.7164.9177.1-55.6-55.7000112.2L261 R265 F285 H287 S503L261-Y263 HydrophobicContact CB-CD2 4.41Å; L261-Y263 HydrophobicContact CB-CE2 4Å; L261-Y263 HydrophobicContact CD2-CE2 3.76Å; L261-Y263 VanDerWaalsContact CD2-OH 3.25Å; L261-Y263 WeakPolarHBondContact CD2-OH 3.25Å; L261-Y263 HydrophobicContact CG-CE2 4.45Å; L261-Y263 PolarHBondContact O-N 2.96Å; Y263-R265 PolarHBondContact O-NE 3.41Å; Y263-F285 HydrophobicContact CD2-CD1 4.49Å; Y263-F285 HydrophobicContact CD2-CD2 4.01Å; Y263-F285 HydrophobicContact CD2-CE1 4.34Å; Y263-F285 AromaticContact CD2-CE2 3.84Å; Y263-F285 HydrophobicContact CD2-CE2 3.84Å; Y263-F285 HydrophobicContact CD2-CG 4.35Å; Y263-F285 HydrophobicContact CD2-CZ 4.01Å; Y263-H287 AromaticContact CD2-CE1 3.65Å; Y263-H287 AromaticContact CG-CE1 3.92Å; Y263-S503 WeakPolarHBondContact CE2-O 3.49Å
264S95.1Very high90.7Very high61 Ų6156.8 Ų56.843%0.42726%0.261SS..  trans-69.5144.7-17970.50000111.8F285 D286S264-F285 WeakPolarHBondContact O-CA 3.31Å; S264-D286 WeakPolarHBondContact CB-OD2 3.45Å; S264-D286 PolarHBondContact O-N 2.76Å; S264-D286 PolarHBondContact OG-OD2 2.8Å
265R97.3Very high91.2Very high32 Ų3261.4 Ų61.412%0.12129%0.285CS..  trans-135.530.9-179.5-66.4159.8-76.81593.2110.2E76 Y263 E267 G268 Q269 L283 P284 F285 D286E76-R265 VanDerWaalsContact CG-NH1 3.27Å; E76-R265 IonicContact OE1-CZ 2.77Å; E76-R265 IonicContact OE1-NE 3.89Å; E76-R265 IonicContact OE1-NH1 3.97Å; E76-R265 PolarHBondContact OE1-NH1 2.81Å; E76-R265 IonicContact OE2-NH1 2.78Å; E76-R265 PolarHBondContact OE2-NH1 3.03Å; Y263-R265 PolarHBondContact O-NE 3.41Å; R265-E267 VanDerWaalsContact C-N 3.33Å; R265-E267 PolarHBondContact O-N 2.94Å; R265-G268 PolarHBondContact O-N 3.16Å; R265-Q269 WeakPolarHBondContact O-CG 3.39Å; R265-Q269 PolarHBondContact O-N 2.89Å; R265-L283 HydrophobicContact CB-CB 3.95Å; R265-L283 HydrophobicContact CB-CD1 4.34Å; R265-L283 HydrophobicContact CG-CB 4.28Å; R265-P284 WeakPolarHBondContact CG-O 3.48Å; R265-F285 HydrophobicContact CG-CD1 3.64Å; R265-F285 HydrophobicContact CG-CE1 4.15Å; R265-D286 VanDerWaalsContact C-OD1 3.26Å; R265-D286 WeakPolarHBondContact CA-OD1 3.37Å; R265-D286 PolarHBondContact N-OD2 3.16Å
266K97.6Very high91.8Very high142 Ų14262.2 Ų62.262%0.61729%0.289SS*.Hα-helixtrans-64.7-37.4-168-68.6179.4-179.6178.10111.5G268 Q269 R270 D286K266-G268 VanDerWaalsContact C-N 3.31Å; K266-G268 PolarHBondContact O-N 2.9Å; K266-Q269 WeakPolarHBondContact O-CB 3.26Å; K266-Q269 PolarHBondContact O-N 2.96Å; K266-R270 PolarHBondContact O-N 3.15Å; K266-D286 VanDerWaalsContact N-CG 3.33Å; K266-D286 PolarHBondContact N-OD1 3.28Å; K266-D286 PolarHBondContact N-OD2 2.8Å
267E98.1Very high92.6Very high49 Ų4961.9 Ų61.923%0.22929%0.288CS..Hα-helixtrans-64.9-37.6-178.4-64.9-54.9133.200111.6R265 Q269 R270 N273 D286 Y304R265-E267 VanDerWaalsContact C-N 3.33Å; R265-E267 PolarHBondContact O-N 2.94Å; E267-Q269 VanDerWaalsContact C-N 3.26Å; E267-Q269 PolarHBondContact O-N 3.37Å; E267-R270 WeakPolarHBondContact O-CB 3.19Å; E267-R270 WeakPolarHBondContact O-CG 3.45Å; E267-R270 PolarHBondContact O-N 3Å; E267-R270 WeakPolarHBondContact OE2-CD 3.35Å; E267-R270 IonicContact OE2-CZ 2.87Å; E267-R270 IonicContact OE2-NE 2.82Å; E267-R270 IonicContact OE2-NH1 3.3Å; E267-R270 PolarHBondContact OE2-NH1 2.84Å; E267-N273 PolarHBondContact O-ND2 3.22Å; E267-D286 PolarHBondContact N-OD1 2.78Å; E267-Y304 HydrophobicContact CB-CD2 4.39Å
268G97.8Very high93.4Very high1 Ų162.8 Ų62.81%0.0129%0.29CS..Hα-helixtrans-70.4-19.717500000114.5R265 K266 N277 Y304R265-G268 PolarHBondContact O-N 3.16Å; K266-G268 VanDerWaalsContact C-N 3.31Å; K266-G268 PolarHBondContact O-N 2.9Å; G268-N277 PolarHBondContact O-ND2 2.86Å; G268-Y304 VanDerWaalsContact CA-CE2 3.46Å; G268-Y304 VanDerWaalsContact CA-OH 3.32Å; G268-Y304 WeakPolarHBondContact CA-OH 3.41Å
269Q97.2Very high94.1Very high111 Ų11163.5 Ų63.552%0.51929%0.293SS..Hα-helixtrans-86.8-13179.3-67.4172.1-24.800113.4R265 K266 E267 L283R265-Q269 WeakPolarHBondContact O-CG 3.39Å; R265-Q269 PolarHBondContact O-N 2.89Å; K266-Q269 WeakPolarHBondContact O-CB 3.26Å; K266-Q269 PolarHBondContact O-N 2.96Å; E267-Q269 VanDerWaalsContact C-N 3.26Å; E267-Q269 PolarHBondContact O-N 3.37Å; Q269-L283 HydrophobicContact CG-CD1 3.47Å; Q269-L283 VanDerWaalsContact CG-CD1 3.47Å
270R97.5Very high94.9Very high92 Ų9267.8 Ų67.835%0.34731%0.31SS..SBendtrans-55.4143.9178.7-69.1178.866.2165.23.2111.4K266 E267 E272 N273 K274K266-R270 PolarHBondContact O-N 3.15Å; E267-R270 WeakPolarHBondContact O-CB 3.19Å; E267-R270 WeakPolarHBondContact O-CG 3.45Å; E267-R270 PolarHBondContact O-N 3Å; E267-R270 WeakPolarHBondContact OE2-CD 3.35Å; E267-R270 IonicContact OE2-CZ 2.87Å; E267-R270 IonicContact OE2-NE 2.82Å; E267-R270 IonicContact OE2-NH1 3.3Å; E267-R270 PolarHBondContact OE2-NH1 2.84Å; R270-E272 IonicContact NE-OE2 3.3Å; R270-E272 PolarHBondContact O-N 3.09Å; R270-N273 HydrophobicContact CB-CB 4.34Å; R270-N273 PolarHBondContact O-N 2.88Å; R270-K274 PolarHBondContact O-N 2.9Å
271Q96.9Very high95.7Very high131 Ų13161.8 Ų61.861%0.61229%0.285SS*.THydrogen-bonded Turntrans-59.1-37.6-172.7-177.756.742.600112N273Q271-N273 VanDerWaalsContact C-N 3.3Å; Q271-N273 PolarHBondContact O-N 2.96Å
272E96.9Very high96.3Very high93 Ų9361 Ų6144%0.43528%0.281SS..THydrogen-bonded Turntrans-69.9-26.2178.9-52.885.4170.300112.5R270 N275 V301R270-E272 IonicContact NE-OE2 3.3Å; R270-E272 PolarHBondContact O-N 3.09Å; E272-N275 PolarHBondContact O-OD1 3.21Å; E272-V301 HydrophobicContact CB-CB 3.98Å; E272-V301 HydrophobicContact CB-CG2 3.88Å; E272-V301 HydrophobicContact CG-CB 4.36Å; E272-V301 HydrophobicContact CG-CG2 3.77Å
273N98.1Very high97Very high0 Ų059.2 Ų59.20%027%0.272CS..THydrogen-bonded Turntrans-96-11.9-175.9-68.4-25.3000113.4E267 R270 Q271 N275 K276 N277 Y304E267-N273 PolarHBondContact O-ND2 3.22Å; R270-N273 HydrophobicContact CB-CB 4.34Å; R270-N273 PolarHBondContact O-N 2.88Å; Q271-N273 VanDerWaalsContact C-N 3.3Å; Q271-N273 PolarHBondContact O-N 2.96Å; N273-N275 VanDerWaalsContact C-N 3.27Å; N273-N275 PolarHBondContact O-N 3.31Å; N273-K276 WeakPolarHBondContact O-CA 3.48Å; N273-K276 WeakPolarHBondContact O-CB 3.27Å; N273-K276 PolarHBondContact O-N 2.98Å; N273-N277 PolarHBondContact O-ND2 3.17Å; N273-N277 VanDerWaalsContact O-ND2 3.12Å; N273-Y304 HydrophobicContact CB-CD1 3.68Å; N273-Y304 HydrophobicContact CB-CD2 4.45Å; N273-Y304 HydrophobicContact CB-CE1 3.89Å; N273-Y304 HydrophobicContact CB-CG 3.98Å; N273-Y304 VanDerWaalsContact CG-CB 3.49Å; N273-Y304 VanDerWaalsContact CG-CD1 3.49Å; N273-Y304 WeakPolarHBondContact ND2-CB 3.26Å; N273-Y304 VanDerWaalsContact ND2-CG 3.33Å; N273-Y304 VanDerWaalsContact OD1-CB 3.26Å; N273-Y304 WeakPolarHBondContact OD1-CB 3.22Å
274K96.7Very high97.3Very high111 Ų11155 Ų5548%0.48326%0.255SS..G310 helixtrans-53.5-42.2-177.4-78.2179.5-179.2171.50113.1R270 K276 N277R270-K274 PolarHBondContact O-N 2.9Å; K274-K276 VanDerWaalsContact C-N 3.29Å; K274-K276 PolarHBondContact O-N 2.78Å; K274-N277 PolarHBondContact O-N 2.93Å
275N97.8Very high97.4Very high105 Ų10552.1 Ų52.156%0.56124%0.235SC*.G310 helixtrans-80.4-6.5179.869.5-3.3000113.7E272 N273 N277 N336E272-N275 PolarHBondContact O-OD1 3.21Å; N273-N275 VanDerWaalsContact C-N 3.27Å; N273-N275 PolarHBondContact O-N 3.31Å; N275-N277 VanDerWaalsContact C-N 3.31Å; N275-N336 PolarHBondContact O-ND2 3.24Å
276K98.5Very high97.5Very high19 Ų1952.1 Ų52.18%0.08324%0.237CC..G310 helixtrans-87.2-5.2173.4-59.2-174.9177.6-1730111.7N273 K274 V301 Y304 Q331 T337 D340N273-K276 WeakPolarHBondContact O-CA 3.48Å; N273-K276 WeakPolarHBondContact O-CB 3.27Å; N273-K276 PolarHBondContact O-N 2.98Å; K274-K276 VanDerWaalsContact C-N 3.29Å; K274-K276 PolarHBondContact O-N 2.78Å; K276-V301 PolarHBondContact NZ-O 3.01Å; K276-Y304 HydrophobicContact CB-CD1 3.94Å; K276-Y304 HydrophobicContact CB-CE1 3.95Å; K276-Y304 HydrophobicContact CD-CD1 3.95Å; K276-Q331 PolarHBondContact O-NE2 2.87Å; K276-T337 HydrophobicContact CB-CG2 3.97Å; K276-T337 HydrophobicContact CG-CG2 4.27Å; K276-D340 IonicContact NZ-OD2 3.97Å
277N98.5Very high97.5Very high14 Ų1450.1 Ų50.18%0.07523%0.23CC..  trans-100.9121.9178.3-58.8-47.7000110.9G268 N273 K274 N275 Y279 L283 Y304 N306G268-N277 PolarHBondContact O-ND2 2.86Å; N273-N277 PolarHBondContact O-ND2 3.17Å; N273-N277 VanDerWaalsContact O-ND2 3.12Å; K274-N277 PolarHBondContact O-N 2.93Å; N275-N277 VanDerWaalsContact C-N 3.31Å; N277-Y279 PolarHBondContact O-N 3.24Å; N277-L283 HydrophobicContact CB-CD2 4.08Å; N277-L283 WeakPolarHBondContact ND2-CD2 3.32Å; N277-Y304 PolarHBondContact OD1-OH 3.47Å; N277-N306 PolarHBondContact OD1-ND2 3.16Å
278R97.9Very high97.5Very high41 Ų4148.6 Ų48.616%0.15522%0.224CC..SBendtrans-63.5-33.5176.2177.6170.8-77.5-83.43.3111.8G332 C333 L334 S365 K366 S464R278-G332 PolarHBondContact NE-O 2.87Å; R278-C333 PolarHBondContact NH2-O 2.86Å; R278-L334 HydrophobicContact CB-CD1 4.44Å; R278-L334 HydrophobicContact CB-CD2 4Å; R278-L334 HydrophobicContact CB-CG 4.31Å; R278-L334 HydrophobicContact CG-CD2 4.16Å; R278-S365 PolarHBondContact NH1-O 2.93Å; R278-K366 PolarHBondContact NE-O 2.8Å; R278-K366 VanDerWaalsContact NE-O 3.16Å; R278-K366 PolarHBondContact NH2-O 2.87Å; R278-S464 WeakPolarHBondContact CD-O 3.29Å
279Y96.7Very high97.6Very high24 Ų2450.4 Ų50.49%0.09423%0.23CC..SBendtrans-127.4123.1173.3-55-73.8000108.9Y62 K70 N277 N281 I282 S464 A465Y62-Y279 HydrophobicContact CD1-CD2 4.46Å; Y62-Y279 HydrophobicContact CD1-CE1 4.12Å; Y62-Y279 HydrophobicContact CD1-CE2 4.06Å; Y62-Y279 AromaticContact CD1-CZ 3.87Å; Y62-Y279 HydrophobicContact CE1-CD1 4.37Å; Y62-Y279 AromaticContact CE1-CE1 3.58Å; Y62-Y279 HydrophobicContact CE1-CE1 3.58Å; Y62-Y279 HydrophobicContact CE1-CE2 4.01Å; Y62-Y279 AromaticContact CE1-CZ 3.37Å; Y62-Y279 WeakPolarHBondContact CE1-OH 3.3Å; K70-Y279 HydrophobicContact CB-CD1 4.42Å; K70-Y279 HydrophobicContact CD-CD1 3.58Å; K70-Y279 HydrophobicContact CD-CE1 3.72Å; N277-Y279 PolarHBondContact O-N 3.24Å; Y279-N281 PolarHBondContact O-N 2.49Å; Y279-N281 VanDerWaalsContact O-N 3.11Å; Y279-I282 HydrophobicContact CD2-CD1 3.92Å; Y279-I282 HydrophobicContact CG-CD1 3.95Å; Y279-I282 PolarHBondContact O-N 2.94Å; Y279-I282 VanDerWaalsContact O-N 3.1Å; Y279-S464 PolarHBondContact OH-OG 3.06Å; Y279-A465 HydrophobicContact CD2-CB 3.72Å; Y279-A465 HydrophobicContact CE2-CB 3.66Å
280K95.2Very high97.6Very high100 Ų10045.2 Ų45.244%0.43521%0.206SC..THydrogen-bonded Turntrans-51.2-37.8-172.8179.3-176.1160.3-166.80114E69 Y80E69-K280 IonicContact OE1-NZ 3.08Å; E69-K280 PolarHBondContact OE1-NZ 2.87Å; Y80-K280 PolarHBondContact OH-NZ 2.81Å
281N94.3Very high97.7Very high16 Ų1643.2 Ų43.29%0.08620%0.204CC..BIsolated β-bridgetrans-108.813.1-175.5-49.5-42.1000113.6E69 K70 F71 Y279E69-N281 VanDerWaalsContact CB-ND2 3.28Å; E69-N281 WeakPolarHBondContact CB-ND2 3.19Å; K70-N281 WeakPolarHBondContact O-CB 3.43Å; F71-N281 HydrophobicContact CD1-CB 3.59Å; F71-N281 HydrophobicContact CE1-CB 3.59Å; F71-N281 WeakPolarHBondContact CE1-ND2 3.21Å; F71-N281 HydrophobicContact CG-CB 4.44Å; F71-N281 HydrophobicContact CZ-CB 4.44Å; F71-N281 VanDerWaalsContact CZ-ND2 3.26Å; F71-N281 WeakPolarHBondContact CZ-ND2 3.33Å; Y279-N281 PolarHBondContact O-N 2.49Å; Y279-N281 VanDerWaalsContact O-N 3.11Å
282I97.7Very high97.8Very high4 Ų437.1 Ų37.12%0.02118%0.176CC..  trans-11195172.9-54.3180000107.6Y62 A72 Y279 N306 A465 I467Y62-I282 HydrophobicContact CD1-CD1 4.34Å; Y62-I282 HydrophobicContact CG-CD1 4.25Å; A72-I282 HydrophobicContact CB-CG1 4.38Å; A72-I282 HydrophobicContact CB-CG2 4.24Å; Y279-I282 HydrophobicContact CD2-CD1 3.92Å; Y279-I282 HydrophobicContact CG-CD1 3.95Å; Y279-I282 PolarHBondContact O-N 2.94Å; Y279-I282 VanDerWaalsContact O-N 3.1Å; I282-N306 PolarHBondContact O-ND2 3.2Å; I282-A465 HydrophobicContact CD1-CB 3.88Å; I282-A465 HydrophobicContact CG2-CB 4.38Å; I282-I467 HydrophobicContact CD1-CD1 4.23Å; I282-I467 HydrophobicContact CG2-CD1 4.13Å; I282-I467 HydrophobicContact CG2-CG2 4.2Å
283L98.5Very high97.7Very high8 Ų838.1 Ų38.14%0.04218%0.18CC..  trans-121.4149.8-167.3-57.9-180000110.8R265 Q269 N277R265-L283 HydrophobicContact CB-CB 3.95Å; R265-L283 HydrophobicContact CB-CD1 4.34Å; R265-L283 HydrophobicContact CG-CB 4.28Å; Q269-L283 HydrophobicContact CG-CD1 3.47Å; Q269-L283 VanDerWaalsContact CG-CD1 3.47Å; N277-L283 HydrophobicContact CB-CD2 4.08Å; N277-L283 WeakPolarHBondContact ND2-CD2 3.32Å
284P98.6Very high97.3Very high0 Ų044.5 Ų44.50%021%0.214CC..  trans-69.5146.1174.532.6-35.7000110.5R265 R289 Y304 N308R265-P284 WeakPolarHBondContact CG-O 3.48Å; P284-R289 HydrophobicContact CB-CB 4.15Å; P284-R289 HydrophobicContact CG-CB 4.42Å; P284-Y304 WeakPolarHBondContact CD-OH 3.48Å; P284-Y304 HydrophobicContact CG-CE2 3.79Å; P284-N308 WeakPolarHBondContact CA-OD1 3.36Å; P284-N308 WeakPolarHBondContact CB-OD1 3.44Å
285F98.4Very high96.9Very high1 Ų140.1 Ų40.10%0.00420%0.201CC..  trans-68141.3167.7-65.9-44000110.9L261 Y263 S264 R265 H287 R289 N308 R502 R505 S506L261-F285 WeakPolarHBondContact O-CZ 3.33Å; Y263-F285 HydrophobicContact CD2-CD1 4.49Å; Y263-F285 HydrophobicContact CD2-CD2 4.01Å; Y263-F285 HydrophobicContact CD2-CE1 4.34Å; Y263-F285 AromaticContact CD2-CE2 3.84Å; Y263-F285 HydrophobicContact CD2-CE2 3.84Å; Y263-F285 HydrophobicContact CD2-CG 4.35Å; Y263-F285 HydrophobicContact CD2-CZ 4.01Å; S264-F285 WeakPolarHBondContact O-CA 3.31Å; R265-F285 HydrophobicContact CG-CD1 3.64Å; R265-F285 HydrophobicContact CG-CE1 4.15Å; F285-H287 VanDerWaalsContact C-N 3.33Å; F285-H287 AromaticContact CD2-CE1 3.92Å; F285-H287 AromaticContact CG-CE1 3.93Å; F285-H287 PolarHBondContact O-N 2.99Å; F285-R289 WeakPolarHBondContact O-CB 3.35Å; F285-R289 PolarHBondContact O-N 3.38Å; F285-N308 PolarHBondContact N-ND2 2.6Å; F285-N308 PolarHBondContact O-ND2 3.06Å; F285-R502 WeakPolarHBondContact CE2-O 3.34Å; F285-R505 VanDerWaalsContact CE2-C 3.49Å; F285-S506 VanDerWaalsContact CE2-N 3.26Å
286D98.4Very high96.4Very high32 Ų3238.9 Ų38.917%0.17119%0.194CC..THydrogen-bonded Turntrans-66.1-34.9-173.7-59-40000112.3S264 R265 K266 E267 T288S264-D286 WeakPolarHBondContact CB-OD2 3.45Å; S264-D286 PolarHBondContact O-N 2.76Å; S264-D286 PolarHBondContact OG-OD2 2.8Å; R265-D286 VanDerWaalsContact C-OD1 3.26Å; R265-D286 WeakPolarHBondContact CA-OD1 3.37Å; R265-D286 PolarHBondContact N-OD2 3.16Å; K266-D286 VanDerWaalsContact N-CG 3.33Å; K266-D286 PolarHBondContact N-OD1 3.28Å; K266-D286 PolarHBondContact N-OD2 2.8Å; E267-D286 PolarHBondContact N-OD1 2.78Å; D286-T288 VanDerWaalsContact C-N 3.32Å; D286-T288 PolarHBondContact O-N 2.86Å
287H98.1Very high95.9Very high100 Ų10044 Ų4446%0.46323%0.23SC..THydrogen-bonded Turntrans-75.8-15.3-173.966.7-74000114.7Y263 F285 S503Y263-H287 AromaticContact CD2-CE1 3.65Å; Y263-H287 AromaticContact CG-CE1 3.92Å; F285-H287 VanDerWaalsContact C-N 3.33Å; F285-H287 AromaticContact CD2-CE1 3.92Å; F285-H287 AromaticContact CG-CE1 3.93Å; F285-H287 PolarHBondContact O-N 2.99Å; H287-S503 PolarHBondContact CE1-O 3.26Å; H287-S503 PolarHBondContact NE2-O 3.1Å; H287-S503 VanDerWaalsContact NE2-O 3.1Å
288T98.2Very high95.5Very high17 Ų1750 Ų5010%0.10426%0.262CS..THydrogen-bonded Turntrans-127.85.2-179.548.80000112.4D286 N308 I309 Q504D286-T288 VanDerWaalsContact C-N 3.32Å; D286-T288 PolarHBondContact O-N 2.86Å; T288-N308 CarbonylContact O-C 3.58Å; T288-N308 WeakPolarHBondContact O-CA 3.5Å; T288-N308 PolarHBondContact O-ND2 3.45Å; T288-N308 PolarHBondContact OG1-ND2 2.88Å; T288-I309 PolarHBondContact O-N 3.06Å; T288-Q504 HydrophobicContact CG2-CB 4.11Å; T288-Q504 HydrophobicContact CG2-CG 4.18Å; T288-Q504 PolarHBondContact OG1-O 3.45Å
289R98.7Very high95.1Very high39 Ų3952.4 Ų52.415%0.14727%0.274CS..EExtended strand (participates in β ladder)trans-62.4149.3179.173.6-179.1-179.795.2-10.6110.2P284 F285 V291 D303 A307 N308P284-R289 HydrophobicContact CB-CB 4.15Å; P284-R289 HydrophobicContact CG-CB 4.42Å; F285-R289 WeakPolarHBondContact O-CB 3.35Å; F285-R289 PolarHBondContact O-N 3.38Å; R289-V291 HydrophobicContact CG-CG2 4.22Å; R289-V291 PolarHBondContact O-N 3.48Å; R289-D303 IonicContact CZ-OD2 3.85Å; R289-D303 PolarHBondContact NH1-O 3.02Å; R289-D303 IonicContact NH1-OD2 2.78Å; R289-D303 PolarHBondContact NH1-OD2 3.37Å; R289-D303 IonicContact NH2-OD2 2.83Å; R289-D303 PolarHBondContact NH2-OD2 2.85Å; R289-A307 VanDerWaalsContact CA-O 3.29Å; R289-A307 WeakPolarHBondContact CA-O 3.46Å; R289-N308 PolarHBondContact N-ND2 3.2Å
290V98.8Very high94.6Very high2 Ų257 Ų571%0.01231%0.307CS..EExtended strand (participates in β ladder)trans-76.3123.4168.2-1710000108.8L292 I305 A307 I309 I328 M344 E348V290-L292 HydrophobicContact CG1-CD2 4.45Å; V290-I305 HydrophobicContact CB-CG2 4Å; V290-I305 HydrophobicContact CG1-CG2 4.5Å; V290-A307 HydrophobicContact CB-CB 4.32Å; V290-A307 HydrophobicContact CG2-CB 3.89Å; V290-A307 PolarHBondContact N-O 3.28Å; V290-I309 HydrophobicContact CG2-CD1 3.7Å; V290-I309 HydrophobicContact CG2-CG1 4.17Å; V290-I328 HydrophobicContact CG2-CD1 4.35Å; V290-I328 HydrophobicContact CG2-CG2 3.98Å; V290-M344 HydrophobicContact CB-CG 4.42Å; V290-M344 HydrophobicContact CG1-CG 3.85Å; V290-M344 HydrophobicContact CG2-SD 4.37Å; V290-E348 HydrophobicContact CG1-CG 4.15Å
291V98.7Very high94.5Very high50 Ų5052.7 Ų52.730%0.30329%0.289SS..EExtended strand (participates in β ladder)trans-97.1118.1177.7-173.50000108R289 D303 Q347R289-V291 HydrophobicContact CG-CG2 4.22Å; R289-V291 PolarHBondContact O-N 3.48Å; V291-D303 HydrophobicContact CG1-CB 4.06Å; V291-Q347 PolarHBondContact O-NE2 2.64Å
292L98.4Very high94.5Very high4 Ų453 Ų532%0.02129%0.293CS..PPolyproline II helixtrans-81.9125.4178.8-56.7-178.6000111V290 D303 I305 D340 M344V290-L292 HydrophobicContact CG1-CD2 4.45Å; L292-D303 PolarHBondContact N-O 3.49Å; L292-D303 VanDerWaalsContact O-CA 3.26Å; L292-D303 WeakPolarHBondContact O-CA 3.29Å; L292-D303 WeakPolarHBondContact O-CB 3.47Å; L292-I305 HydrophobicContact CD1-CB 4.03Å; L292-I305 HydrophobicContact CD1-CG2 4.24Å; L292-I305 HydrophobicContact CD2-CG2 3.98Å; L292-I305 HydrophobicContact CG-CB 4.33Å; L292-I305 HydrophobicContact CG-CG2 4Å; L292-D340 HydrophobicContact CD1-CB 3.78Å; L292-M344 HydrophobicContact CD2-CB 3.73Å; L292-M344 HydrophobicContact CD2-CG 4.29Å
293H95.1Very high94.5Very high113 Ų11354.5 Ų54.552%0.52330%0.301SS..  trans-94.4175.6173.7-54.3-50000110.5G295 R343 Q347H293-G295 PolarHBondContact O-N 3.48Å; H293-R343 PolarHBondContact O-NH2 3.32Å; H293-Q347 PolarHBondContact CD2-OE1 3.44Å
294D90.8Very high94.5Very high135 Ų13554.1 Ų54.172%0.72230%0.299SS*.SBendtrans48.139.4177.9-59-14.7000114K405D294-K405 IonicContact OD2-NZ 2.94Å
295G88.1Confident94.5Very high19 Ų1954.5 Ų54.520%0.19630%0.301CS..  trans-73.2168.7174.800000112.5H293 P297 S302 R343H293-G295 PolarHBondContact O-N 3.48Å; G295-P297 VanDerWaalsContact O-CD 3.29Å; G295-P297 WeakPolarHBondContact O-CD 3.29Å; G295-S302 WeakPolarHBondContact CA-OG 3.49Å; G295-R343 VanDerWaalsContact CA-NH2 3.26Å
296D87.5Confident94.5Very high79 Ų7954.5 Ų54.542%0.42230%0.301SS..  trans-62.8120174.8-172.4-17.6000109.4N298 E299D296-N298 PolarHBondContact O-N 2.79Å; D296-N298 VanDerWaalsContact OD1-CB 3.31Å; D296-N298 WeakPolarHBondContact OD1-CB 3.28Å; D296-N298 PolarHBondContact OD1-N 3.18Å; D296-N298 PolarHBondContact OD1-ND2 3Å; D296-E299 HydrophobicContact CB-CB 4.33Å; D296-E299 HydrophobicContact CB-CG 4.21Å; D296-E299 PolarHBondContact O-N 3.36Å
297P88.2Confident94.6Very high127 Ų12753 Ų5383%0.82529%0.293SS*.THydrogen-bonded Turntrans-59.2-18.3177-23.134.4000113.8G295G295-P297 VanDerWaalsContact O-CD 3.29Å; G295-P297 WeakPolarHBondContact O-CD 3.29Å
298N90.2Very high94.6Very high140 Ų14048.2 Ų48.275%0.74927%0.271SS*.THydrogen-bonded Turntrans-84.4-15.1176.4-54.8-64.1000113.2D296 P300D296-N298 PolarHBondContact O-N 2.79Å; D296-N298 VanDerWaalsContact OD1-CB 3.31Å; D296-N298 WeakPolarHBondContact OD1-CB 3.28Å; D296-N298 PolarHBondContact OD1-N 3.18Å; D296-N298 PolarHBondContact OD1-ND2 3Å; N298-P300 WeakPolarHBondContact O-CD 3.4Å
299E88.2Confident94.6Very high90 Ų9049.3 Ų49.342%0.42128%0.275SS..SBendtrans-84.3122.8172.3-81.1-166.2171.800110D296 V301D296-E299 HydrophobicContact CB-CB 4.33Å; D296-E299 HydrophobicContact CB-CG 4.21Å; D296-E299 PolarHBondContact O-N 3.36Å; E299-V301 PolarHBondContact O-N 3.26Å; E299-V301 VanDerWaalsContact O-N 3.15Å
300P86.8Confident94.6Very high121 Ų12147.4 Ų47.479%0.78627%0.268SS*.SBendtrans-59.2-30.2179.2-25.634.1000113.9N298N298-P300 WeakPolarHBondContact O-CD 3.4Å
301V92.1Very high94.4Very high9 Ų950.7 Ų50.76%0.05528%0.284CS..  trans-140.392.8-179.1-173.40000110.2E272 K276 E299 D303E272-V301 HydrophobicContact CB-CB 3.98Å; E272-V301 HydrophobicContact CB-CG2 3.88Å; E272-V301 HydrophobicContact CG-CB 4.36Å; E272-V301 HydrophobicContact CG-CG2 3.77Å; K276-V301 PolarHBondContact NZ-O 3.01Å; E299-V301 PolarHBondContact O-N 3.26Å; E299-V301 VanDerWaalsContact O-N 3.15Å; V301-D303 WeakPolarHBondContact CG1-OD1 3.29Å
302S95Very high93.8Very high24 Ų2449.5 Ų49.517%0.16828%0.278CS..  trans-109.25.3-17864.60000113.9G295 R343G295-S302 WeakPolarHBondContact CA-OG 3.49Å; S302-R343 PolarHBondContact O-NH1 3.31Å; S302-R343 PolarHBondContact O-NH2 2.94Å
303D97.9Very high92.7Very high35 Ų3553.2 Ų53.219%0.18730%0.295CS..SBendtrans-100.40.1-170.681.5-47.3000114.5R289 V291 L292 V301R289-D303 IonicContact CZ-OD2 3.85Å; R289-D303 PolarHBondContact NH1-O 3.02Å; R289-D303 IonicContact NH1-OD2 2.78Å; R289-D303 PolarHBondContact NH1-OD2 3.37Å; R289-D303 IonicContact NH2-OD2 2.83Å; R289-D303 PolarHBondContact NH2-OD2 2.85Å; V291-D303 HydrophobicContact CG1-CB 4.06Å; L292-D303 PolarHBondContact N-O 3.49Å; L292-D303 VanDerWaalsContact O-CA 3.26Å; L292-D303 WeakPolarHBondContact O-CA 3.29Å; L292-D303 WeakPolarHBondContact O-CB 3.47Å; V301-D303 WeakPolarHBondContact CG1-OD1 3.29Å
304Y98.7Very high90.8Very high0 Ų054.8 Ų54.80%030%0.301CS..EExtended strand (participates in β ladder)trans-104.2133.5-171.5-178.5-96.3000113.4E267 G268 N273 K276 N277 P284 N306E267-Y304 HydrophobicContact CB-CD2 4.39Å; G268-Y304 VanDerWaalsContact CA-CE2 3.46Å; G268-Y304 VanDerWaalsContact CA-OH 3.32Å; G268-Y304 WeakPolarHBondContact CA-OH 3.41Å; N273-Y304 HydrophobicContact CB-CD1 3.68Å; N273-Y304 HydrophobicContact CB-CD2 4.45Å; N273-Y304 HydrophobicContact CB-CE1 3.89Å; N273-Y304 HydrophobicContact CB-CG 3.98Å; N273-Y304 VanDerWaalsContact CG-CB 3.49Å; N273-Y304 VanDerWaalsContact CG-CD1 3.49Å; N273-Y304 WeakPolarHBondContact ND2-CB 3.26Å; N273-Y304 VanDerWaalsContact ND2-CG 3.33Å; N273-Y304 VanDerWaalsContact OD1-CB 3.26Å; N273-Y304 WeakPolarHBondContact OD1-CB 3.22Å; K276-Y304 HydrophobicContact CB-CD1 3.94Å; K276-Y304 HydrophobicContact CB-CE1 3.95Å; K276-Y304 HydrophobicContact CD-CD1 3.95Å; N277-Y304 PolarHBondContact OD1-OH 3.47Å; P284-Y304 WeakPolarHBondContact CD-OH 3.48Å; P284-Y304 HydrophobicContact CG-CE2 3.79Å; Y304-N306 HydrophobicContact CE1-CB 4.47Å
305I98.8Very high88.5Confident8 Ų855.3 Ų55.34%0.04130%0.299CS..EExtended strand (participates in β ladder)trans-140.5146.2161.1-173.6162.8000109V290 L292 A307 D340 F341 M344V290-I305 HydrophobicContact CB-CG2 4Å; V290-I305 HydrophobicContact CG1-CG2 4.5Å; L292-I305 HydrophobicContact CD1-CB 4.03Å; L292-I305 HydrophobicContact CD1-CG2 4.24Å; L292-I305 HydrophobicContact CD2-CG2 3.98Å; L292-I305 HydrophobicContact CG-CB 4.33Å; L292-I305 HydrophobicContact CG-CG2 4Å; I305-A307 HydrophobicContact CG1-CB 4.46Å; I305-A307 HydrophobicContact CG2-CB 4.05Å; I305-A307 PolarHBondContact O-N 2.93Å; I305-D340 HydrophobicContact CD1-CB 4.26Å; I305-F341 HydrophobicContact CD1-CB 4.42Å; I305-M344 HydrophobicContact CD1-CB 4.01Å; I305-M344 HydrophobicContact CD1-CE 4.48Å; I305-M344 HydrophobicContact CD1-CG 4.45Å; I305-M344 HydrophobicContact CD1-SD 3.82Å; I305-M344 HydrophobicContact CG2-CG 4.46Å; I305-M344 HydrophobicContact CG2-SD 4.16Å
306N98.8Very high86.1Confident1 Ų159.3 Ų59.31%0.00532%0.319CS..EExtended strand (participates in β ladder)trans-77.474.8176-168.4-39.5000110.7N277 I282 Y304 T330 Q331 R505N277-N306 PolarHBondContact OD1-ND2 3.16Å; I282-N306 PolarHBondContact O-ND2 3.2Å; Y304-N306 HydrophobicContact CE1-CB 4.47Å; N306-T330 PolarHBondContact O-OG1 3.37Å; N306-Q331 HydrophobicContact CB-CG 4.07Å; N306-Q331 PolarHBondContact ND2-OE1 2.94Å; N306-Q331 PolarHBondContact O-N 2.68Å; N306-R505 PolarHBondContact OD1-NH1 3.35Å; N306-R505 VanDerWaalsContact OD1-NH1 3.09Å; N306-R505 PolarHBondContact OD1-NH2 3.24Å
307A98.9Very high83.8Confident0 Ų063.5 Ų63.50%033%0.334CS..EExtended strand (participates in β ladder)trans-147.6151.2-179.200000111.1R289 V290 I305 I328 A329 M344R289-A307 VanDerWaalsContact CA-O 3.29Å; R289-A307 WeakPolarHBondContact CA-O 3.46Å; V290-A307 HydrophobicContact CB-CB 4.32Å; V290-A307 HydrophobicContact CG2-CB 3.89Å; V290-A307 PolarHBondContact N-O 3.28Å; I305-A307 HydrophobicContact CG1-CB 4.46Å; I305-A307 HydrophobicContact CG2-CB 4.05Å; I305-A307 PolarHBondContact O-N 2.93Å; A307-I328 HydrophobicContact CB-CG2 3.84Å; A307-A329 CarbonylContact C-O 3.54Å; A307-A329 VanDerWaalsContact CA-O 3.3Å; A307-A329 WeakPolarHBondContact CA-O 3.45Å; A307-M344 HydrophobicContact CB-SD 3.65Å
308N98.9Very high81.4Confident0 Ų061.7 Ų61.70%032%0.323CS..EExtended strand (participates in β ladder)trans-129.4141.5172.7-6696.1000111.1P284 F285 T288 R289 I310 I328 A329 Q504 R505P284-N308 WeakPolarHBondContact CA-OD1 3.36Å; P284-N308 WeakPolarHBondContact CB-OD1 3.44Å; F285-N308 PolarHBondContact N-ND2 2.6Å; F285-N308 PolarHBondContact O-ND2 3.06Å; T288-N308 CarbonylContact O-C 3.58Å; T288-N308 WeakPolarHBondContact O-CA 3.5Å; T288-N308 PolarHBondContact O-ND2 3.45Å; T288-N308 PolarHBondContact OG1-ND2 2.88Å; R289-N308 PolarHBondContact N-ND2 3.2Å; N308-I310 HydrophobicContact CB-CD1 4.26Å; N308-I328 CarbonylContact O-C 3.49Å; N308-I328 WeakPolarHBondContact O-CA 3.46Å; N308-A329 PolarHBondContact N-O 2.74Å; N308-A329 PolarHBondContact O-N 2.67Å; N308-Q504 WeakPolarHBondContact CB-O 3.33Å; N308-Q504 PolarHBondContact ND2-O 3.46Å; N308-R505 HydrophobicContact CB-CB 4.02Å; N308-R505 HydrophobicContact CB-CG 4.43Å; N308-R505 WeakPolarHBondContact OD1-CG 3.38Å; N308-R505 PolarHBondContact OD1-NH1 3.46Å
309I98.7Very high79.1Confident39 Ų3962.3 Ų62.320%0.233%0.326CS..EExtended strand (participates in β ladder)trans-67.9133.6163.3-55-56.7000108.3T288 V290 M311 Y327 I328T288-I309 PolarHBondContact O-N 3.06Å; V290-I309 HydrophobicContact CG2-CD1 3.7Å; V290-I309 HydrophobicContact CG2-CG1 4.17Å; I309-M311 HydrophobicContact CG2-CG 3.98Å; I309-Y327 CarbonylContact C-O 3.54Å; I309-Y327 WeakPolarHBondContact CA-O 3.35Å; I309-I328 HydrophobicContact CD1-CD1 3.97Å; I309-I328 HydrophobicContact CD1-CG1 3.73Å
310I98.1Very high77Confident0 Ų065.9 Ų65.90%035%0.349CS..EExtended strand (participates in β ladder)trans-120.1120173.6-47.5-63.7000108.4N308 Y327 A329 I474 V501 Q504 R505 M508N308-I310 HydrophobicContact CB-CD1 4.26Å; I310-Y327 PolarHBondContact N-O 3.47Å; I310-Y327 PolarHBondContact O-N 2.86Å; I310-A329 HydrophobicContact CD1-CB 4.16Å; I310-A329 HydrophobicContact CG1-CB 3.76Å; I310-I474 HydrophobicContact CG1-CD1 4.42Å; I310-I474 HydrophobicContact CG2-CG2 4.21Å; I310-V501 HydrophobicContact CG2-CB 4.39Å; I310-V501 HydrophobicContact CG2-CG1 3.88Å; I310-V501 HydrophobicContact CG2-CG2 4.06Å; I310-Q504 HydrophobicContact CD1-CB 3.7Å; I310-R505 HydrophobicContact CD1-CB 3.89Å; I310-M508 HydrophobicContact CD1-CE 4.46Å; I310-M508 HydrophobicContact CG1-CE 4.48Å
311M95.2Very high75.4Confident70 Ų7063.7 Ų63.735%0.34534%0.336SS..  trans-109.9133.2179-60.6-175.2-74.700110I309 E313 Q504I309-M311 HydrophobicContact CG2-CG 3.98Å; M311-E313 VanDerWaalsContact C-N 3.26Å; M311-E313 PolarHBondContact O-N 2.66Å; M311-Q504 PolarHBondContact O-NE2 3.46Å
312P86.2Confident73.8Confident26 Ų2671.8 Ų71.817%0.16937%0.37CS..SBendtrans-71-12.2-175.525.9-33.6000115.1K324 K325 I478 M500P312-K324 HydrophobicContact CG-CB 3.99Å; P312-K324 HydrophobicContact CG-CD 4.39Å; P312-K325 WeakPolarHBondContact CD-O 3.31Å; P312-K325 WeakPolarHBondContact CG-O 3.43Å; P312-I478 HydrophobicContact CB-CD1 4.17Å; P312-I478 HydrophobicContact CB-CG1 4.06Å; P312-I478 HydrophobicContact CB-CG2 4.05Å; P312-M500 VanDerWaalsContact O-CE 3.25Å; P312-M500 WeakPolarHBondContact O-CE 3.47Å
313E74.3Confident72.2Confident81 Ų8176.9 Ų76.938%0.37940%0.403SS..SBendtrans-148.8143.2173.1-92.7162.3-164.600109.2M311 E315 K324M311-E313 VanDerWaalsContact C-N 3.26Å; M311-E313 PolarHBondContact O-N 2.66Å; E313-E315 PolarHBondContact O-N 3.21Å; E313-K324 IonicContact OE1-NZ 2.98Å; E313-K324 PolarHBondContact OE1-NZ 3.48Å; E313-K324 IonicContact OE2-NZ 3.48Å; E313-K324 PolarHBondContact OE2-NZ 2.62Å
314F54.6Low71.1Confident147 Ų14778.8 Ų78.865%0.64541%0.41SS*.SBendtrans-74.5108.3165.1-114.2-93.5000106.8T316F314-T316 PolarHBondContact O-N 2.88Å
315E42.8Very low70.6Confident146 Ų14680.1 Ų80.168%0.68242%0.416SS*.  trans-16.288.9-178.5-64.8-176.9176.400116E313 K317E313-E315 PolarHBondContact O-N 3.21Å; E315-K317 PolarHBondContact O-N 2.99Å
316T39.1Very low70.4Confident103 Ų10381.4 Ų81.463%0.63243%0.425SS*.  trans-81.799.3146.934.20000106F314 C318F314-T316 PolarHBondContact O-N 2.88Å; T316-C318 PolarHBondContact O-N 2.99Å
317K38.7Very low70.4Confident167 Ų16781.4 Ų81.473%0.72643%0.425SS*.  trans-58.580.1171.8-68.8-179.6178178.90110.1E315E315-K317 PolarHBondContact O-N 2.99Å
318C38.5Very low70.4Confident89 Ų8981.4 Ų81.460%0.60143%0.425SS*.  trans-86.9104.8159-68.30000105.7T316 N320 S321T316-C318 PolarHBondContact O-N 2.99Å; C318-N320 PolarHBondContact O-N 2.88Å; C318-S321 PolarHBondContact O-N 3.26Å
319N41.6Very low70.4Confident152 Ų15281.4 Ų81.481%0.81343%0.425SS*.THydrogen-bonded Turntrans-598.8-169.7-79-16.7000116.6
320N43.5Very low70.4Confident166 Ų16679.7 Ų79.789%0.88842%0.416SS*.THydrogen-bonded Turntrans-135.64.1-173.5-78.4-13.2000115.6C318C318-N320 PolarHBondContact O-N 2.88Å
321S53.8Low70.5Confident75 Ų7580 Ų8052%0.52442%0.418SS..SBendtrans-90.3137.817760.60000111.8C318C318-S321 PolarHBondContact O-N 3.26Å
322K57.5Low70.6Confident178 Ų17876.7 Ų76.777%0.77440%0.402SS*.PPolyproline II helixtrans-49.8141.7168.3-72.3-177.8179179.90109.8K324K322-K324 PolarHBondContact O-N 3.36Å; K322-K324 VanDerWaalsContact O-N 3.13Å
323P61.7Low71.2Confident131 Ų13175.6 Ų75.685%0.85139%0.394SS*.PPolyproline II helixtrans-57121.3175.720.9-29.4000109.5
324K74.6Confident72.4Confident75 Ų7573.1 Ų73.133%0.32638%0.384SS..PPolyproline II helixtrans-67.5146.8177.9-75.8-177.2176.6171.40110.3P312 E313 K322 S326P312-K324 HydrophobicContact CG-CB 3.99Å; P312-K324 HydrophobicContact CG-CD 4.39Å; E313-K324 IonicContact OE1-NZ 2.98Å; E313-K324 PolarHBondContact OE1-NZ 3.48Å; E313-K324 IonicContact OE2-NZ 3.48Å; E313-K324 PolarHBondContact OE2-NZ 2.62Å; K322-K324 PolarHBondContact O-N 3.36Å; K322-K324 VanDerWaalsContact O-N 3.13Å; K324-S326 PolarHBondContact O-N 2.91Å
325K88.1Confident74.5Confident29 Ų2973.4 Ų73.413%0.12639%0.387CS..PPolyproline II helixtrans-54.3124.2174.6-172.1175.672.2-1570110.3P312 Y327 H447 Q450 V459 D477 D481P312-K325 WeakPolarHBondContact CD-O 3.31Å; P312-K325 WeakPolarHBondContact CG-O 3.43Å; K325-Y327 HydrophobicContact CD-CE1 4.46Å; K325-Y327 WeakPolarHBondContact CE-OH 3.35Å; K325-Y327 HydrophobicContact CG-CE1 4.43Å; K325-H447 PolarHBondContact NZ-ND1 3.28Å; K325-Q450 HydrophobicContact CD-CG 4.01Å; K325-Q450 HydrophobicContact CG-CG 4.22Å; K325-V459 HydrophobicContact CD-CG2 4.18Å; K325-V459 HydrophobicContact CG-CG2 4.21Å; K325-D477 WeakPolarHBondContact CE-OD2 3.31Å; K325-D477 IonicContact NZ-OD1 3.78Å; K325-D477 PolarHBondContact NZ-OD1 2.79Å; K325-D477 IonicContact NZ-OD2 2.84Å; K325-D477 PolarHBondContact NZ-OD2 3.42Å; K325-D481 WeakPolarHBondContact CE-OD2 3.4Å; K325-D481 IonicContact NZ-OD1 3.03Å; K325-D481 PolarHBondContact NZ-OD1 2.9Å; K325-D481 IonicContact NZ-OD2 3.91Å; K325-D481 PolarHBondContact NZ-OD2 3Å
326S95.6Very high77.1Confident35 Ų3570.2 Ų70.225%0.24537%0.374CS..  trans-109.7166.817557.50000110.7K324 P458 V459K324-S326 PolarHBondContact O-N 2.91Å; S326-P458 CarbonylContact O-C 3.55Å; S326-P458 VanDerWaalsContact O-CA 3.23Å; S326-P458 WeakPolarHBondContact O-CA 3.47Å; S326-P458 WeakPolarHBondContact O-CB 3.46Å; S326-P458 WeakPolarHBondContact OG-CB 3.49Å; S326-V459 PolarHBondContact O-N 2.82Å
327Y98.7Very high80Confident1 Ų165.6 Ų65.60%0.00435%0.346CS..EExtended strand (participates in β ladder)trans-132.1159.5-173.5-45.1-94000112I309 I310 K325 V459 V461 I474 D477 I478I309-Y327 CarbonylContact C-O 3.54Å; I309-Y327 WeakPolarHBondContact CA-O 3.35Å; I310-Y327 PolarHBondContact N-O 3.47Å; I310-Y327 PolarHBondContact O-N 2.86Å; K325-Y327 HydrophobicContact CD-CE1 4.46Å; K325-Y327 WeakPolarHBondContact CE-OH 3.35Å; K325-Y327 HydrophobicContact CG-CE1 4.43Å; Y327-V459 CarbonylContact C-O 3.51Å; Y327-V459 VanDerWaalsContact CA-O 3.26Å; Y327-V459 WeakPolarHBondContact CA-O 3.26Å; Y327-V459 HydrophobicContact CD1-CB 4.16Å; Y327-V461 HydrophobicContact CD1-CG2 4.29Å; Y327-I474 HydrophobicContact CD1-CG1 4.08Å; Y327-I474 HydrophobicContact CD2-CG2 3.9Å; Y327-I474 HydrophobicContact CE2-CG2 4.14Å; Y327-I474 HydrophobicContact CG-CD1 4.33Å; Y327-I474 HydrophobicContact CG-CG1 4.14Å; Y327-I474 HydrophobicContact CG-CG2 4.11Å; Y327-D477 HydrophobicContact CE1-CB 4.46Å; Y327-D477 WeakPolarHBondContact CE1-OD2 3.29Å; Y327-D477 PolarHBondContact OH-OD2 3.18Å; Y327-D477 VanDerWaalsContact OH-OD2 3.09Å; Y327-I478 HydrophobicContact CE2-CD1 4.02Å; Y327-I478 HydrophobicContact CE2-CG1 3.67Å
328I98.9Very high82.8Confident0 Ų058 Ų580%031%0.314CS..EExtended strand (participates in β ladder)trans-116.8112.3163-57.6-173.8000108V290 A307 N308 I309 M344 E348 P458 V459 V460 V461V290-I328 HydrophobicContact CG2-CD1 4.35Å; V290-I328 HydrophobicContact CG2-CG2 3.98Å; A307-I328 HydrophobicContact CB-CG2 3.84Å; N308-I328 CarbonylContact O-C 3.49Å; N308-I328 WeakPolarHBondContact O-CA 3.46Å; I309-I328 HydrophobicContact CD1-CD1 3.97Å; I309-I328 HydrophobicContact CD1-CG1 3.73Å; I328-M344 HydrophobicContact CD1-CG 4.38Å; I328-M344 HydrophobicContact CD1-SD 4.45Å; I328-M344 HydrophobicContact CG2-CE 4.06Å; I328-M344 HydrophobicContact CG2-SD 3.73Å; I328-E348 HydrophobicContact CD1-CB 3.83Å; I328-E348 HydrophobicContact CD1-CG 3.66Å; I328-P458 HydrophobicContact CD1-CB 4.44Å; I328-P458 HydrophobicContact CD1-CG 3.67Å; I328-P458 HydrophobicContact CG1-CB 3.88Å; I328-P458 HydrophobicContact CG1-CG 3.63Å; I328-V459 PolarHBondContact N-O 2.87Å; I328-V460 HydrophobicContact CB-CG2 4.18Å; I328-V460 HydrophobicContact CD1-CG2 4.23Å; I328-V460 HydrophobicContact CG1-CG2 4.48Å; I328-V461 PolarHBondContact O-N 2.97Å
329A98.9Very high85.7Confident0 Ų057.2 Ų57.20%030%0.304CS..EExtended strand (participates in β ladder)trans-88.3117.7171.400000109.4A307 N308 I310 T470 I474 M508A307-A329 CarbonylContact C-O 3.54Å; A307-A329 VanDerWaalsContact CA-O 3.3Å; A307-A329 WeakPolarHBondContact CA-O 3.45Å; N308-A329 PolarHBondContact N-O 2.74Å; N308-A329 PolarHBondContact O-N 2.67Å; I310-A329 HydrophobicContact CD1-CB 4.16Å; I310-A329 HydrophobicContact CG1-CB 3.76Å; A329-T470 HydrophobicContact CB-CG2 3.77Å; A329-I474 HydrophobicContact CB-CD1 4Å; A329-M508 HydrophobicContact CB-CE 3.9Å; A329-M508 HydrophobicContact CB-SD 4.37Å
330T98.9Very high88.4Confident2 Ų250.6 Ų50.61%0.01227%0.268CS..EExtended strand (participates in β ladder)trans-135.4161.5-177-170.20000112.6N306 F341 M344 V460 V461 H462 G466N306-T330 PolarHBondContact O-OG1 3.37Å; T330-F341 HydrophobicContact CG2-CE2 4.13Å; T330-M344 HydrophobicContact CG2-CE 4.29Å; T330-V460 HydrophobicContact CG2-CG1 3.87Å; T330-V461 PolarHBondContact N-O 3.34Å; T330-V461 VanDerWaalsContact N-O 3.09Å; T330-H462 HydrophobicContact CG2-CB 3.57Å; T330-H462 WeakPolarHBondContact O-CA 3.33Å; T330-H462 WeakPolarHBondContact O-CB 3.07Å; T330-G466 WeakPolarHBondContact O-CA 3.47Å
331Q98.8Very high91Very high8 Ų842.8 Ų42.84%0.03723%0.226CC..PPolyproline II helixtrans-74.8163.717572.4177.420.900111.9K276 N306 C333 S464K276-Q331 PolarHBondContact O-NE2 2.87Å; N306-Q331 HydrophobicContact CB-CG 4.07Å; N306-Q331 PolarHBondContact ND2-OE1 2.94Å; N306-Q331 PolarHBondContact O-N 2.68Å; Q331-C333 PolarHBondContact O-N 3.16Å; Q331-S464 WeakPolarHBondContact CB-O 3.49Å
332G98.7Very high93.2Very high0 Ų039.2 Ų39.20%020%0.201CC..PPolyproline II helixtrans-65.3130.3168.500000110.7R278 C463 S464R278-G332 PolarHBondContact NE-O 2.87Å; G332-C463 WeakPolarHBondContact CA-O 3.36Å; G332-C463 PolarHBondContact N-O 2.76Å; G332-C463 VanDerWaalsContact N-O 3.1Å; G332-S464 PolarHBondContact N-O 2.82Å
333C98.8Very high95.1Very high2 Ų231.9 Ų31.91%0.01417%0.169CC..PPolyproline II helixtrans-50.9139.6-175.1-73.30000112.4R278 Q331 V338 F341 C367 V368 Y370R278-C333 PolarHBondContact NH2-O 2.86Å; Q331-C333 PolarHBondContact O-N 3.16Å; C333-V338 HydrophobicContact CB-CG2 4.3Å; C333-F341 WeakPolarHBondContact SG-CG 3.44Å; C333-C367 PolarHBondContact N-SG 3.29Å; C333-V368 HydrophobicContact CB-CG2 3.87Å; C333-V368 WeakPolarHBondContact O-CG2 3.39Å; C333-V368 PolarHBondContact O-N 3.09Å; C333-Y370 HydrophobicContact CB-CD1 4.23Å
334L98.7Very high96.9Very high30 Ų3025.7 Ų25.716%0.15713%0.128CC..PPolyproline II helixtrans-95.7162.8164.2-61.9171000109.2R278 N336 T337 V338R278-L334 HydrophobicContact CB-CD1 4.44Å; R278-L334 HydrophobicContact CB-CD2 4Å; R278-L334 HydrophobicContact CB-CG 4.31Å; R278-L334 HydrophobicContact CG-CD2 4.16Å; L334-N336 VanDerWaalsContact CB-OD1 3.25Å; L334-N336 WeakPolarHBondContact CB-OD1 3.4Å; L334-N336 PolarHBondContact O-N 3.02Å; L334-T337 HydrophobicContact CB-CG2 4.12Å; L334-T337 HydrophobicContact CD1-CG2 4.27Å; L334-T337 PolarHBondContact N-OG1 2.94Å; L334-T337 PolarHBondContact O-N 3.3Å; L334-T337 PolarHBondContact O-OG1 2.92Å; L334-V338 WeakPolarHBondContact O-CG2 3.48Å; L334-V338 PolarHBondContact O-N 3.02Å
335Q98.4Very high98Very high152 Ų15222.1 Ų22.171%0.7111%0.113SC*.G310 helixtrans-54.8-40.6178.9-17062.535.800112.4
336N98.1Very high98.5Very high79 Ų7922.5 Ų22.542%0.42212%0.115SC..G310 helixtrans-84.3-2.2-179.763.1-45.5000114.3N275 L334N275-N336 PolarHBondContact O-ND2 3.24Å; L334-N336 VanDerWaalsContact CB-OD1 3.25Å; L334-N336 WeakPolarHBondContact CB-OD1 3.4Å; L334-N336 PolarHBondContact O-N 3.02Å
337T98.6Very high98.6Very high7 Ų723.5 Ų23.54%0.04312%0.115CC..G310 helixtrans-1173.9-179.871.90000113.1K276 L334 N339 D340 F341K276-T337 HydrophobicContact CB-CG2 3.97Å; K276-T337 HydrophobicContact CG-CG2 4.27Å; L334-T337 HydrophobicContact CB-CG2 4.12Å; L334-T337 HydrophobicContact CD1-CG2 4.27Å; L334-T337 PolarHBondContact N-OG1 2.94Å; L334-T337 PolarHBondContact O-N 3.3Å; L334-T337 PolarHBondContact O-OG1 2.92Å; T337-N339 VanDerWaalsContact C-N 3.3Å; T337-N339 PolarHBondContact O-N 2.8Å; T337-D340 PolarHBondContact O-N 3.43Å; T337-F341 WeakPolarHBondContact O-CB 3.24Å; T337-F341 PolarHBondContact O-N 3.21Å
338V98.8Very high98.6Very high6 Ų625.9 Ų25.94%0.03613%0.127CC..Hα-helixtrans-60.7-41177.9172.50000111.3C333 L334 F341 W342 V368 Y380C333-V338 HydrophobicContact CB-CG2 4.3Å; L334-V338 WeakPolarHBondContact O-CG2 3.48Å; L334-V338 PolarHBondContact O-N 3.02Å; V338-F341 WeakPolarHBondContact O-CB 3.44Å; V338-F341 PolarHBondContact O-N 3.4Å; V338-W342 PolarHBondContact O-N 3.28Å; V338-V368 HydrophobicContact CG2-CG2 3.57Å; V338-Y380 HydrophobicContact CG1-CD1 3.33Å; V338-Y380 HydrophobicContact CG1-CE1 3.64Å; V338-Y380 HydrophobicContact CG1-CG 4.03Å
339N98.4Very high98.5Very high74 Ų7428.1 Ų28.140%0.39614%0.139SC..Hα-helixtrans-66.7-44.9179.1-61.2-6.7000110.8T337 F341 W342 R343 Y380 G381T337-N339 VanDerWaalsContact C-N 3.3Å; T337-N339 PolarHBondContact O-N 2.8Å; N339-F341 VanDerWaalsContact C-N 3.29Å; N339-F341 PolarHBondContact O-N 3.48Å; N339-W342 PolarHBondContact O-N 3.42Å; N339-R343 WeakPolarHBondContact O-CG 3.42Å; N339-R343 PolarHBondContact O-N 2.72Å; N339-Y380 VanDerWaalsContact OD1-C 3.27Å; N339-Y380 WeakPolarHBondContact OD1-CA 3.42Å; N339-G381 PolarHBondContact OD1-N 2.71Å
340D98.7Very high98.5Very high13 Ų1328.1 Ų28.17%0.0714%0.139CC..Hα-helixtrans-60.7-38.1175.8-70.2-25.8000112K276 L292 I305 T337 R343 M344K276-D340 IonicContact NZ-OD2 3.97Å; L292-D340 HydrophobicContact CD1-CB 3.78Å; I305-D340 HydrophobicContact CD1-CB 4.26Å; T337-D340 PolarHBondContact O-N 3.43Å; D340-R343 WeakPolarHBondContact O-CB 3.44Å; D340-R343 PolarHBondContact O-N 2.77Å; D340-R343 IonicContact OD1-CZ 3.74Å; D340-R343 IonicContact OD1-NH1 2.85Å; D340-R343 PolarHBondContact OD1-NH1 3.02Å; D340-M344 WeakPolarHBondContact O-CB 3.05Å; D340-M344 PolarHBondContact O-N 2.98Å
341F98.9Very high98.5Very high1 Ų130.4 Ų30.40%0.00415%0.147CC..Hα-helixtrans-60.9-46174.9178.3-92.3000111.9I305 T330 C333 T337 V338 N339 M344 V345 I353 Y370 V460I305-F341 HydrophobicContact CD1-CB 4.42Å; T330-F341 HydrophobicContact CG2-CE2 4.13Å; C333-F341 WeakPolarHBondContact SG-CG 3.44Å; T337-F341 WeakPolarHBondContact O-CB 3.24Å; T337-F341 PolarHBondContact O-N 3.21Å; V338-F341 WeakPolarHBondContact O-CB 3.44Å; V338-F341 PolarHBondContact O-N 3.4Å; N339-F341 VanDerWaalsContact C-N 3.29Å; N339-F341 PolarHBondContact O-N 3.48Å; F341-M344 HydrophobicContact CD2-CE 3.93Å; F341-M344 HydrophobicContact CE2-CE 3.97Å; F341-M344 WeakPolarHBondContact O-CB 3.45Å; F341-M344 PolarHBondContact O-N 3.29Å; F341-V345 HydrophobicContact CD1-CG2 4.13Å; F341-V345 HydrophobicContact CE1-CG2 3.7Å; F341-V345 HydrophobicContact CE2-CG2 4.49Å; F341-V345 HydrophobicContact CZ-CG2 3.9Å; F341-V345 WeakPolarHBondContact O-CG2 3.09Å; F341-V345 PolarHBondContact O-N 3.45Å; F341-I353 HydrophobicContact CE1-CD1 3.98Å; F341-I353 HydrophobicContact CZ-CD1 4.02Å; F341-I353 HydrophobicContact CZ-CG2 4.14Å; F341-Y370 AromaticContact CD1-CD2 3.94Å; F341-Y370 HydrophobicContact CD1-CD2 3.94Å; F341-Y370 HydrophobicContact CD1-CE2 4.27Å; F341-Y370 HydrophobicContact CD1-CG 4.36Å; F341-Y370 AromaticContact CE1-CD2 3.6Å; F341-Y370 HydrophobicContact CE1-CD2 3.6Å; F341-Y370 AromaticContact CE1-CE2 3.47Å; F341-Y370 HydrophobicContact CE1-CE2 3.47Å; F341-Y370 VanDerWaalsContact CE1-CE2 3.47Å; F341-Y370 HydrophobicContact CE1-CG 4.32Å; F341-Y370 HydrophobicContact CZ-CD2 4.41Å; F341-Y370 AromaticContact CZ-CE2 3.94Å; F341-Y370 HydrophobicContact CZ-CE2 3.94Å; F341-V460 HydrophobicContact CE2-CG1 3.89Å; F341-V460 HydrophobicContact CZ-CG1 4.15Å
342W98.8Very high98.5Very high0 Ų030 Ų300%015%0.145CC..Hα-helixtrans-70.5-31.5177.5-74.9117000113.1V338 N339 V345 F346 I353 Y370 Y380 M383 V385 L401 L403V338-W342 PolarHBondContact O-N 3.28Å; N339-W342 PolarHBondContact O-N 3.42Å; W342-V345 HydrophobicContact CE3-CB 4.11Å; W342-V345 HydrophobicContact CE3-CG1 4.18Å; W342-V345 HydrophobicContact CE3-CG2 4.35Å; W342-V345 HydrophobicContact CZ3-CB 4.47Å; W342-V345 HydrophobicContact CZ3-CG1 4.12Å; W342-F346 VanDerWaalsContact O-CB 3.28Å; W342-F346 WeakPolarHBondContact O-CB 3.2Å; W342-F346 PolarHBondContact O-N 3.12Å; W342-I353 HydrophobicContact CH2-CD1 4.15Å; W342-I353 HydrophobicContact CZ3-CD1 4.15Å; W342-Y370 HydrophobicContact CH2-CD2 4.5Å; W342-Y370 AromaticContact CZ2-CD2 3.69Å; W342-Y370 HydrophobicContact CZ2-CD2 3.69Å; W342-Y370 HydrophobicContact CZ2-CE2 4.16Å; W342-Y370 WeakPolarHBondContact CZ2-O 3.36Å; W342-Y370 PolarHBondContact NE1-O 3.48Å; W342-Y380 AromaticContact CD1-CD2 3.56Å; W342-Y380 AromaticContact CD1-CG 3.64Å; W342-Y380 HydrophobicContact CG-CD2 4.42Å; W342-Y380 AromaticContact NE1-CD2 3.51Å; W342-Y380 AromaticContact NE1-CE2 3.7Å; W342-Y380 AromaticContact NE1-CG 3.94Å; W342-M383 HydrophobicContact CB-CB 3.8Å; W342-M383 HydrophobicContact CB-CG 3.92Å; W342-V385 HydrophobicContact CD2-CG2 3.72Å; W342-V385 HydrophobicContact CE3-CG2 3.97Å; W342-V385 HydrophobicContact CG-CG2 4.25Å; W342-V385 HydrophobicContact CH2-CG1 4.06Å; W342-V385 HydrophobicContact CH2-CG2 4.1Å; W342-V385 HydrophobicContact CZ2-CB 4.45Å; W342-V385 HydrophobicContact CZ2-CG1 3.98Å; W342-V385 HydrophobicContact CZ2-CG2 3.85Å; W342-V385 HydrophobicContact CZ3-CG2 4.15Å; W342-L401 HydrophobicContact CH2-CD1 3.74Å; W342-L401 HydrophobicContact CZ2-CD1 4.33Å; W342-L403 HydrophobicContact CE3-CD1 3.87Å; W342-L403 HydrophobicContact CE3-CD2 4.06Å; W342-L403 HydrophobicContact CE3-CG 4.5Å; W342-L403 HydrophobicContact CZ3-CD1 4.41Å; W342-L403 HydrophobicContact CZ3-CD2 4.29Å
343R98.3Very high98.5Very high25 Ų2530 Ų309%0.09415%0.145CC..Hα-helixtrans-59.9-47.7169.3-72.1170.961.4-143.3-1.2111.3H293 G295 S302 N339 D340 F346 Q347 M383H293-R343 PolarHBondContact O-NH2 3.32Å; G295-R343 VanDerWaalsContact CA-NH2 3.26Å; S302-R343 PolarHBondContact O-NH1 3.31Å; S302-R343 PolarHBondContact O-NH2 2.94Å; N339-R343 WeakPolarHBondContact O-CG 3.42Å; N339-R343 PolarHBondContact O-N 2.72Å; D340-R343 WeakPolarHBondContact O-CB 3.44Å; D340-R343 PolarHBondContact O-N 2.77Å; D340-R343 IonicContact OD1-CZ 3.74Å; D340-R343 IonicContact OD1-NH1 2.85Å; D340-R343 PolarHBondContact OD1-NH1 3.02Å; R343-F346 PolarHBondContact O-N 3.34Å; R343-Q347 VanDerWaalsContact O-CB 3.3Å; R343-Q347 WeakPolarHBondContact O-CB 3.38Å; R343-Q347 PolarHBondContact O-N 3.38Å; R343-M383 HydrophobicContact CG-CE 4.25Å
344M98.8Very high98.5Very high0 Ų029.9 Ų29.90%015%0.145CC..Hα-helixtrans-57.5-54.3175.6-173.7-169.468.900111.2V290 L292 I305 A307 I328 T330 D340 F341 F346 Q347 E348 V460V290-M344 HydrophobicContact CB-CG 4.42Å; V290-M344 HydrophobicContact CG1-CG 3.85Å; V290-M344 HydrophobicContact CG2-SD 4.37Å; L292-M344 HydrophobicContact CD2-CB 3.73Å; L292-M344 HydrophobicContact CD2-CG 4.29Å; I305-M344 HydrophobicContact CD1-CB 4.01Å; I305-M344 HydrophobicContact CD1-CE 4.48Å; I305-M344 HydrophobicContact CD1-CG 4.45Å; I305-M344 HydrophobicContact CD1-SD 3.82Å; I305-M344 HydrophobicContact CG2-CG 4.46Å; I305-M344 HydrophobicContact CG2-SD 4.16Å; A307-M344 HydrophobicContact CB-SD 3.65Å; I328-M344 HydrophobicContact CD1-CG 4.38Å; I328-M344 HydrophobicContact CD1-SD 4.45Å; I328-M344 HydrophobicContact CG2-CE 4.06Å; I328-M344 HydrophobicContact CG2-SD 3.73Å; T330-M344 HydrophobicContact CG2-CE 4.29Å; D340-M344 WeakPolarHBondContact O-CB 3.05Å; D340-M344 PolarHBondContact O-N 2.98Å; F341-M344 HydrophobicContact CD2-CE 3.93Å; F341-M344 HydrophobicContact CE2-CE 3.97Å; F341-M344 WeakPolarHBondContact O-CB 3.45Å; F341-M344 PolarHBondContact O-N 3.29Å; M344-F346 VanDerWaalsContact C-N 3.3Å; M344-F346 PolarHBondContact O-N 2.95Å; M344-Q347 PolarHBondContact O-N 3.4Å; M344-E348 HydrophobicContact CG-CG 4.44Å; M344-E348 WeakPolarHBondContact O-CB 3.31Å; M344-E348 WeakPolarHBondContact O-CG 3.47Å; M344-E348 PolarHBondContact O-N 3.38Å; M344-V460 HydrophobicContact CE-CG1 3.83Å; M344-V460 HydrophobicContact CE-CG2 4.14Å
345V98.8Very high98.5Very high0 Ų028.5 Ų28.50%014%0.137CC..Hα-helixtrans-54.5-51.9179.3172.30000109F341 W342 N349 S350 I353 L403 R417 V419 V460F341-V345 HydrophobicContact CD1-CG2 4.13Å; F341-V345 HydrophobicContact CE1-CG2 3.7Å; F341-V345 HydrophobicContact CE2-CG2 4.49Å; F341-V345 HydrophobicContact CZ-CG2 3.9Å; F341-V345 WeakPolarHBondContact O-CG2 3.09Å; F341-V345 PolarHBondContact O-N 3.45Å; W342-V345 HydrophobicContact CE3-CB 4.11Å; W342-V345 HydrophobicContact CE3-CG1 4.18Å; W342-V345 HydrophobicContact CE3-CG2 4.35Å; W342-V345 HydrophobicContact CZ3-CB 4.47Å; W342-V345 HydrophobicContact CZ3-CG1 4.12Å; V345-N349 PolarHBondContact O-N 3.1Å; V345-S350 PolarHBondContact O-N 3.18Å; V345-I353 HydrophobicContact CG1-CD1 4.45Å; V345-I353 HydrophobicContact CG2-CD1 4.06Å; V345-L403 HydrophobicContact CB-CD2 4.42Å; V345-L403 HydrophobicContact CG1-CD2 3.76Å; V345-R417 VanDerWaalsContact C-NH2 3.26Å; V345-R417 PolarHBondContact O-NH2 3.19Å; V345-V419 HydrophobicContact CG1-CG1 4.37Å; V345-V419 HydrophobicContact CG1-CG2 4.24Å; V345-V460 HydrophobicContact CG2-CG2 4.32Å
346F98.3Very high98.5Very high38 Ų3821.3 Ų21.317%0.16710%0.104CC..Hα-helixtrans-56.4-55.3179.8-169.7-93000112.4W342 R343 M344 E348 N349 M383 L403 K405 R417W342-F346 VanDerWaalsContact O-CB 3.28Å; W342-F346 WeakPolarHBondContact O-CB 3.2Å; W342-F346 PolarHBondContact O-N 3.12Å; R343-F346 PolarHBondContact O-N 3.34Å; M344-F346 VanDerWaalsContact C-N 3.3Å; M344-F346 PolarHBondContact O-N 2.95Å; F346-E348 PolarHBondContact O-N 3.4Å; F346-N349 PolarHBondContact O-N 3.45Å; F346-M383 HydrophobicContact CB-CE 3.56Å; F346-M383 HydrophobicContact CB-SD 3.79Å; F346-M383 HydrophobicContact CD1-CE 3.69Å; F346-M383 HydrophobicContact CD1-SD 4.34Å; F346-M383 HydrophobicContact CD2-CE 4.36Å; F346-M383 HydrophobicContact CD2-SD 3.94Å; F346-M383 HydrophobicContact CE1-CE 4.49Å; F346-M383 HydrophobicContact CG-CE 3.6Å; F346-M383 HydrophobicContact CG-SD 3.75Å; F346-L403 HydrophobicContact CB-CD2 4.09Å; F346-L403 HydrophobicContact CD2-CD2 4.08Å; F346-L403 HydrophobicContact CD2-CG 4.09Å; F346-K405 HydrophobicContact CE1-CD 4.27Å; F346-K405 HydrophobicContact CE2-CB 4.2Å; F346-K405 HydrophobicContact CZ-CB 3.99Å; F346-K405 HydrophobicContact CZ-CD 4.46Å; F346-R417 PolarHBondContact O-NH1 3.46Å; F346-R417 PolarHBondContact O-NH2 2.92Å
347Q97.9Very high98.5Very high55 Ų5517.6 Ų17.626%0.2578%0.084SC..Hα-helixtrans-56.5-48.2-177.7178180-6500112.3V291 H293 R343 M344 N349V291-Q347 PolarHBondContact O-NE2 2.64Å; H293-Q347 PolarHBondContact CD2-OE1 3.44Å; R343-Q347 VanDerWaalsContact O-CB 3.3Å; R343-Q347 WeakPolarHBondContact O-CB 3.38Å; R343-Q347 PolarHBondContact O-N 3.38Å; M344-Q347 PolarHBondContact O-N 3.4Å; Q347-N349 PolarHBondContact O-N 3.37Å; Q347-N349 VanDerWaalsContact O-N 3.1Å
348E98.1Very high98.4Very high52 Ų5221.3 Ų21.324%0.24310%0.099CC..THydrogen-bonded Turntrans-78.34.8-173.9-59.7-57.8133.300112.7V290 I328 M344 F346 S350 G457 P458V290-E348 HydrophobicContact CG1-CG 4.15Å; I328-E348 HydrophobicContact CD1-CB 3.83Å; I328-E348 HydrophobicContact CD1-CG 3.66Å; M344-E348 HydrophobicContact CG-CG 4.44Å; M344-E348 WeakPolarHBondContact O-CB 3.31Å; M344-E348 WeakPolarHBondContact O-CG 3.47Å; M344-E348 PolarHBondContact O-N 3.38Å; F346-E348 PolarHBondContact O-N 3.4Å; E348-S350 PolarHBondContact O-N 3.01Å; E348-G457 WeakPolarHBondContact O-CA 3.36Å; E348-P458 HydrophobicContact CB-CG 4.2Å; E348-P458 WeakPolarHBondContact O-CD 3.4Å
349N97.6Very high98.3Very high47 Ų4724.3 Ų24.325%0.25111%0.113SC..THydrogen-bonded Turntrans53.524.6-175.5-167.233.1000113.6V345 F346 Q347 R351 D455 G457V345-N349 PolarHBondContact O-N 3.1Å; F346-N349 PolarHBondContact O-N 3.45Å; Q347-N349 PolarHBondContact O-N 3.37Å; Q347-N349 VanDerWaalsContact O-N 3.1Å; N349-R351 PolarHBondContact ND2-NH2 3.14Å; N349-R351 WeakPolarHBondContact O-CD 3.19Å; N349-R351 WeakPolarHBondContact O-CG 3.49Å; N349-R351 PolarHBondContact O-N 3.26Å; N349-R351 PolarHBondContact O-NE 3.13Å; N349-R351 VanDerWaalsContact OD1-CZ 3.23Å; N349-R351 PolarHBondContact OD1-NE 2.92Å; N349-R351 PolarHBondContact OD1-NH2 3.26Å; N349-D455 PolarHBondContact ND2-O 2.8Å; N349-G457 PolarHBondContact O-N 2.98Å
350S98.6Very high98.3Very high0 Ų024.7 Ų24.70%012%0.118CC..  trans-62.4133.6179.3-65.40000110.9V345 E348 R417 P458 V460V345-S350 PolarHBondContact O-N 3.18Å; E348-S350 PolarHBondContact O-N 3.01Å; S350-R417 PolarHBondContact O-NH2 2.72Å; S350-P458 VanDerWaalsContact CB-O 3.26Å; S350-P458 WeakPolarHBondContact CB-O 3.49Å; S350-P458 PolarHBondContact OG-O 2.74Å; S350-V460 WeakPolarHBondContact OG-CG2 3.39Å
351R98.7Very high98Very high49 Ų4924.3 Ų24.319%0.18512%0.116CC..  trans-115.6-15.7-176.3-53-57.4-175.581.61.7113.4N349 V419 W420 I453 A456N349-R351 PolarHBondContact ND2-NH2 3.14Å; N349-R351 WeakPolarHBondContact O-CD 3.19Å; N349-R351 WeakPolarHBondContact O-CG 3.49Å; N349-R351 PolarHBondContact O-N 3.26Å; N349-R351 PolarHBondContact O-NE 3.13Å; N349-R351 VanDerWaalsContact OD1-CZ 3.23Å; N349-R351 PolarHBondContact OD1-NE 2.92Å; N349-R351 PolarHBondContact OD1-NH2 3.26Å; R351-V419 CarbonylContact O-C 3.51Å; R351-V419 WeakPolarHBondContact O-CA 3.4Å; R351-W420 PolarHBondContact O-N 3.09Å; R351-I453 HydrophobicContact CB-CD1 3.84Å; R351-I453 HydrophobicContact CB-CG2 4.32Å; R351-I453 HydrophobicContact CG-CG2 3.94Å; R351-A456 HydrophobicContact CB-CB 4.04Å; R351-A456 HydrophobicContact CG-CB 3.63Å
352V98.9Very high97.6Very high0 Ų032.8 Ų32.80%015%0.148CC..EExtended strand (participates in β ladder)trans-129132.2178.9-176.20000109.4V354 W420 Y422 V446 K449 Q450 V459 V460V352-V354 HydrophobicContact CG1-CG2 4.41Å; V352-W420 WeakPolarHBondContact CA-O 3.45Å; V352-Y422 HydrophobicContact CG1-CD2 3.83Å; V352-Y422 HydrophobicContact CG1-CE2 4.14Å; V352-V446 HydrophobicContact CG1-CG1 4.1Å; V352-K449 HydrophobicContact CG2-CG 4Å; V352-Q450 HydrophobicContact CG2-CB 4.28Å; V352-V459 HydrophobicContact CB-CG1 4.21Å; V352-V459 HydrophobicContact CB-CG2 4.39Å; V352-V459 HydrophobicContact CG1-CG1 4.1Å; V352-V460 PolarHBondContact O-N 3.49Å
353I98.9Very high97.3Very high0 Ų036.3 Ų36.30%018%0.183CC..EExtended strand (participates in β ladder)trans-120.5125.4174.8-58.4169000108.4F341 W342 V345 Y370 V419 W420 Q421 Y422 V460F341-I353 HydrophobicContact CE1-CD1 3.98Å; F341-I353 HydrophobicContact CZ-CD1 4.02Å; F341-I353 HydrophobicContact CZ-CG2 4.14Å; W342-I353 HydrophobicContact CH2-CD1 4.15Å; W342-I353 HydrophobicContact CZ3-CD1 4.15Å; V345-I353 HydrophobicContact CG1-CD1 4.45Å; V345-I353 HydrophobicContact CG2-CD1 4.06Å; I353-Y370 HydrophobicContact CD1-CE2 4.49Å; I353-Y370 WeakPolarHBondContact CG2-OH 3.21Å; I353-V419 HydrophobicContact CD1-CG1 3.55Å; I353-V419 HydrophobicContact CG1-CG1 3.8Å; I353-W420 PolarHBondContact N-O 3.39Å; I353-Q421 HydrophobicContact CB-CB 4.47Å; I353-Q421 HydrophobicContact CB-CG 4.25Å; I353-Q421 HydrophobicContact CG2-CG 4.29Å; I353-Q421 CarbonylContact O-C 3.58Å; I353-Q421 WeakPolarHBondContact O-CA 3.11Å; I353-Y422 PolarHBondContact O-N 3.22Å; I353-V460 CarbonylContact C-O 3.54Å; I353-V460 WeakPolarHBondContact CA-O 3.44Å; I353-V460 HydrophobicContact CG1-CB 4.22Å; I353-V460 HydrophobicContact CG2-CB 4.46Å; I353-V460 HydrophobicContact CG2-CG1 4.47Å
354V98.9Very high97Very high0 Ų041.4 Ų41.40%021%0.206CC..EExtended strand (participates in β ladder)trans-108.2117.8175.8178.70000109.3V352 T356 Y422 F442 V446 V459 V460 V461 H462 F473V352-V354 HydrophobicContact CG1-CG2 4.41Å; V354-T356 HydrophobicContact CG1-CG2 3.85Å; V354-Y422 CarbonylContact C-O 3.57Å; V354-Y422 WeakPolarHBondContact CA-O 3.23Å; V354-F442 HydrophobicContact CG1-CE1 3.73Å; V354-F442 HydrophobicContact CG1-CZ 3.93Å; V354-V446 HydrophobicContact CG2-CG1 3.85Å; V354-V446 HydrophobicContact CG2-CG2 3.94Å; V354-V459 HydrophobicContact CG2-CG1 3.86Å; V354-V460 PolarHBondContact N-O 3.43Å; V354-V461 HydrophobicContact CB-CB 4.42Å; V354-V461 HydrophobicContact CB-CG1 4.14Å; V354-V461 HydrophobicContact CB-CG2 4.17Å; V354-V461 HydrophobicContact CG1-CG1 4.11Å; V354-V461 WeakPolarHBondContact O-CA 3.34Å; V354-H462 PolarHBondContact O-N 2.95Å; V354-F473 HydrophobicContact CB-CE1 4.39Å; V354-F473 HydrophobicContact CG1-CD1 4.21Å; V354-F473 HydrophobicContact CG1-CD2 4.42Å; V354-F473 HydrophobicContact CG1-CE1 3.96Å; V354-F473 HydrophobicContact CG1-CE2 4.19Å; V354-F473 HydrophobicContact CG1-CG 4.44Å; V354-F473 HydrophobicContact CG1-CZ 3.94Å; V354-F473 HydrophobicContact CG2-CE1 4.08Å; V354-F473 HydrophobicContact CG2-CZ 4.16Å
355M98.8Very high96.9Very high0 Ų044.2 Ų44.20%023%0.226CC..EExtended strand (participates in β ladder)trans-110.9117.1176.2175.5167.9176.200109.2T357 E359 C367 Y370 W371 Y422 H423 F424 H462M355-T357 HydrophobicContact CE-CG2 4.29Å; M355-T357 WeakPolarHBondContact CE-O 3.44Å; M355-E359 HydrophobicContact CE-CG 4.31Å; M355-C367 HydrophobicContact CE-CB 3.98Å; M355-Y370 HydrophobicContact SD-CE1 4.15Å; M355-W371 HydrophobicContact CE-CH2 4.04Å; M355-W371 HydrophobicContact CE-CZ3 4.23Å; M355-W371 HydrophobicContact SD-CH2 3.93Å; M355-W371 HydrophobicContact SD-CZ3 3.75Å; M355-Y422 PolarHBondContact N-O 2.98Å; M355-H423 HydrophobicContact CB-CB 4.33Å; M355-H423 CarbonylContact O-C 3.54Å; M355-F424 PolarHBondContact O-N 2.82Å; M355-H462 WeakPolarHBondContact CG-CE1 3.46Å
356T98.3Very high96.9Very high1 Ų145 Ų451%0.00623%0.229CC..  trans-109.629.9-174.358.50000113.7V354 H462 C463 R469V354-T356 HydrophobicContact CG1-CG2 3.85Å; T356-H462 PolarHBondContact N-O 3.42Å; T356-H462 PolarHBondContact OG1-O 3.5Å; T356-C463 WeakPolarHBondContact OG1-CB 3.46Å; T356-R469 WeakPolarHBondContact O-CD 3.43Å; T356-R469 PolarHBondContact O-NH1 3.39Å; T356-R469 VanDerWaalsContact O-NH1 3.07Å
357T97.1Very high96.9Very high1 Ų143.2 Ų43.21%0.00622%0.222CC..SBendtrans-150.1151178.5-171.10000110.1M355 E361 K366 C367 H423M355-T357 HydrophobicContact CE-CG2 4.29Å; M355-T357 WeakPolarHBondContact CE-O 3.44Å; T357-E361 PolarHBondContact OG1-OE1 3.06Å; T357-K366 HydrophobicContact CG2-CB 4.18Å; T357-K366 WeakPolarHBondContact OG1-CB 3.23Å; T357-C367 HydrophobicContact CG2-CB 4.26Å; T357-H423 PolarHBondContact O-NE2 3.49Å
358K97.4Very high96.9Very high86 Ų8641.9 Ų41.937%0.37422%0.217SC..  trans-71161.8165.2-66173.8179.8122.10109.8V360 E361 R425K358-V360 VanDerWaalsContact C-N 3.26Å; K358-V360 PolarHBondContact O-N 2.8Å; K358-E361 HydrophobicContact CB-CG 3.96Å; K358-E361 PolarHBondContact N-OE1 3.09Å; K358-E361 VanDerWaalsContact N-OE1 3.09Å; K358-R425 WeakPolarHBondContact CE-O 3.45Å; K358-R425 PolarHBondContact NZ-O 3.3Å; K358-R425 VanDerWaalsContact NZ-O 3.15Å
359E96.9Very high96.9Very high69 Ų6942.5 Ų42.532%0.32222%0.219SC..SBendtrans-59.7-39.4175.3-66176.6-135.800112.1M355 S365 K366 C367 W371M355-E359 HydrophobicContact CE-CG 4.31Å; E359-S365 CarbonylContact O-C 3.6Å; E359-S365 WeakPolarHBondContact O-CA 3.46Å; E359-K366 PolarHBondContact O-N 3.31Å; E359-C367 WeakPolarHBondContact CA-O 3.45Å; E359-C367 PolarHBondContact O-N 3.21Å; E359-W371 HydrophobicContact CG-CH2 4.03Å; E359-W371 WeakPolarHBondContact OE1-CZ2 3.3Å
360V96.8Very high97Very high81 Ų8140.3 Ų40.349%0.49121%0.207SC..EExtended strand (participates in β ladder)trans-132.1130.6178.5-178.70000109.2K358 K364K358-V360 VanDerWaalsContact C-N 3.26Å; K358-V360 PolarHBondContact O-N 2.8Å; V360-K364 WeakPolarHBondContact CA-O 3.35Å
361E93.3Very high97Very high6 Ų640.4 Ų40.43%0.02821%0.208CC..EExtended strand (participates in β ladder)trans-129.9130.2174.8-66.6177.8-172.300108.4T357 K358 G363 K364 K366 R469T357-E361 PolarHBondContact OG1-OE1 3.06Å; K358-E361 HydrophobicContact CB-CG 3.96Å; K358-E361 PolarHBondContact N-OE1 3.09Å; K358-E361 VanDerWaalsContact N-OE1 3.09Å; E361-G363 PolarHBondContact O-N 3.24Å; E361-G363 VanDerWaalsContact O-N 3.16Å; E361-K364 PolarHBondContact N-O 2.89Å; E361-K364 PolarHBondContact O-N 2.94Å; E361-K366 HydrophobicContact CB-CG 3.94Å; E361-K366 HydrophobicContact CG-CG 4.03Å; E361-R469 IonicContact OE1-CZ 3.98Å; E361-R469 IonicContact OE1-NH1 3.5Å; E361-R469 PolarHBondContact OE1-NH1 3.03Å; E361-R469 IonicContact OE1-NH2 3.39Å; E361-R469 IonicContact OE2-CZ 2.96Å; E361-R469 IonicContact OE2-NH1 3.67Å; E361-R469 PolarHBondContact OE2-NH1 3.18Å; E361-R469 IonicContact OE2-NH2 3.47Å; E361-R469 PolarHBondContact OE2-NH2 2.78Å
362R90.1Very high97Very high179 Ų17938.3 Ų38.368%0.67520%0.201SC*.THydrogen-bonded Turntrans47.540.9-175.3-50.6-174.466.4-149.83.1114.1K364 D429 H430R362-K364 PolarHBondContact O-N 3.24Å; R362-D429 HydrophobicContact CG-CB 4.11Å; R362-D429 WeakPolarHBondContact CG-OD2 3.46Å; R362-H430 PolarHBondContact NH1-NE2 3.19Å
363G92.3Very high97Very high73 Ų7343.3 Ų43.375%0.75323%0.227SC*.THydrogen-bonded Turntrans72.97-179.900000115.2E361E361-G363 PolarHBondContact O-N 3.24Å; E361-G363 VanDerWaalsContact O-N 3.16Å
364K93.4Very high97Very high132 Ų13246.3 Ų46.357%0.57424%0.241SC*.EExtended strand (participates in β ladder)trans-109.4128.9176.3-64.1-179.1-178.6178.60110.1V360 E361 R362 K366V360-K364 WeakPolarHBondContact CA-O 3.35Å; E361-K364 PolarHBondContact N-O 2.89Å; E361-K364 PolarHBondContact O-N 2.94Å; R362-K364 PolarHBondContact O-N 3.24Å; K364-K366 PolarHBondContact O-N 3.31Å
365S96.8Very high96.9Very high59 Ų5952.9 Ų52.941%0.41327%0.267SS..EExtended strand (participates in β ladder)trans-64.5122.4173.5174.60000110.4R278 E359R278-S365 PolarHBondContact NH1-O 2.93Å; E359-S365 CarbonylContact O-C 3.6Å; E359-S365 WeakPolarHBondContact O-CA 3.46Å
366K97.4Very high96.9Very high17 Ų1754.7 Ų54.77%0.07428%0.282CS..SBendtrans-99.5-34.4176.6-62.2-63.7-167.41600111.9D61 R278 T357 E359 E361 K364D61-K366 IonicContact OD2-NZ 3.17Å; D61-K366 PolarHBondContact OD2-NZ 2.94Å; R278-K366 PolarHBondContact NE-O 2.8Å; R278-K366 VanDerWaalsContact NE-O 3.16Å; R278-K366 PolarHBondContact NH2-O 2.87Å; T357-K366 HydrophobicContact CG2-CB 4.18Å; T357-K366 WeakPolarHBondContact OG1-CB 3.23Å; E359-K366 PolarHBondContact O-N 3.31Å; E361-K366 HydrophobicContact CB-CG 3.94Å; E361-K366 HydrophobicContact CG-CG 4.03Å; K364-K366 PolarHBondContact O-N 3.31Å
367C98.5Very high96.9Very high1 Ų158.7 Ų58.71%0.00730%0.303CS..SBendtrans-154.5136.4178-173.50000109.1C333 M355 T357 E359C333-C367 PolarHBondContact N-SG 3.29Å; M355-C367 HydrophobicContact CE-CB 3.98Å; T357-C367 HydrophobicContact CG2-CB 4.26Å; E359-C367 WeakPolarHBondContact CA-O 3.45Å; E359-C367 PolarHBondContact O-N 3.21Å
368V98.5Very high96.9Very high26 Ų2663.7 Ų63.716%0.15832%0.324CS..  trans-80.1148.6171.5-53.60000110.2C333 V338 Y370C333-V368 HydrophobicContact CB-CG2 3.87Å; C333-V368 WeakPolarHBondContact O-CG2 3.39Å; C333-V368 PolarHBondContact O-N 3.09Å; V338-V368 HydrophobicContact CG2-CG2 3.57Å; V368-Y370 WeakPolarHBondContact O-CD1 3.34Å; V368-Y370 PolarHBondContact O-N 3.04Å; V368-Y370 VanDerWaalsContact O-N 3.07Å
369K98.7Very high97Very high66 Ų6664.3 Ų64.329%0.28733%0.329SS..  trans-62.4108.8173.4-173.9164.1-178-76.40111.2W371 D373K369-W371 HydrophobicContact CD-CZ2 4.26Å; K369-W371 HydrophobicContact CG-CD2 3.9Å; K369-W371 HydrophobicContact CG-CE3 4.25Å; K369-W371 HydrophobicContact CG-CG 4.38Å; K369-W371 HydrophobicContact CG-CH2 4.26Å; K369-W371 HydrophobicContact CG-CZ2 3.91Å; K369-W371 HydrophobicContact CG-CZ3 4.43Å; K369-W371 WeakPolarHBondContact CG-O 3.47Å; K369-W371 PolarHBondContact NZ-O 2.91Å; K369-D373 VanDerWaalsContact CE-OD1 3.26Å; K369-D373 WeakPolarHBondContact CE-OD1 3.45Å; K369-D373 IonicContact NZ-OD1 3.96Å; K369-D373 PolarHBondContact NZ-OD1 2.8Å
370Y98.8Very high97Very high0 Ų061.5 Ų61.50%032%0.315CS..  trans-1015.2179.960.7-94.5000113.3C333 F341 W342 I353 M355 V368 Y380 Q421 H462C333-Y370 HydrophobicContact CB-CD1 4.23Å; F341-Y370 AromaticContact CD1-CD2 3.94Å; F341-Y370 HydrophobicContact CD1-CD2 3.94Å; F341-Y370 HydrophobicContact CD1-CE2 4.27Å; F341-Y370 HydrophobicContact CD1-CG 4.36Å; F341-Y370 AromaticContact CE1-CD2 3.6Å; F341-Y370 HydrophobicContact CE1-CD2 3.6Å; F341-Y370 AromaticContact CE1-CE2 3.47Å; F341-Y370 HydrophobicContact CE1-CE2 3.47Å; F341-Y370 VanDerWaalsContact CE1-CE2 3.47Å; F341-Y370 HydrophobicContact CE1-CG 4.32Å; F341-Y370 HydrophobicContact CZ-CD2 4.41Å; F341-Y370 AromaticContact CZ-CE2 3.94Å; F341-Y370 HydrophobicContact CZ-CE2 3.94Å; W342-Y370 HydrophobicContact CH2-CD2 4.5Å; W342-Y370 AromaticContact CZ2-CD2 3.69Å; W342-Y370 HydrophobicContact CZ2-CD2 3.69Å; W342-Y370 HydrophobicContact CZ2-CE2 4.16Å; W342-Y370 WeakPolarHBondContact CZ2-O 3.36Å; W342-Y370 PolarHBondContact NE1-O 3.48Å; I353-Y370 HydrophobicContact CD1-CE2 4.49Å; I353-Y370 WeakPolarHBondContact CG2-OH 3.21Å; M355-Y370 HydrophobicContact SD-CE1 4.15Å; V368-Y370 WeakPolarHBondContact O-CD1 3.34Å; V368-Y370 PolarHBondContact O-N 3.04Å; V368-Y370 VanDerWaalsContact O-N 3.07Å; Y370-Y380 WeakPolarHBondContact O-CE2 3.35Å; Y370-Y380 VanDerWaalsContact O-CZ 3.24Å; Y370-Y380 PolarHBondContact O-OH 2.78Å; Y370-Q421 PolarHBondContact OH-NE2 3.01Å; Y370-H462 AromaticContact CE1-CE1 3.7Å; Y370-H462 AromaticContact CE1-NE2 3.5Å; Y370-H462 WeakPolarHBondContact CE1-NE2 3.5Å; Y370-H462 AromaticContact CZ-NE2 3.54Å; Y370-H462 PolarHBondContact OH-NE2 3.49Å
371W98.8Very high96.9Very high2 Ų259.9 Ų59.91%0.00832%0.315CS..SBendtrans-118.7149.2178.863.795.6000111.1M355 E359 K369 Y380 R399 L401 Q421M355-W371 HydrophobicContact CE-CH2 4.04Å; M355-W371 HydrophobicContact CE-CZ3 4.23Å; M355-W371 HydrophobicContact SD-CH2 3.93Å; M355-W371 HydrophobicContact SD-CZ3 3.75Å; E359-W371 HydrophobicContact CG-CH2 4.03Å; E359-W371 WeakPolarHBondContact OE1-CZ2 3.3Å; K369-W371 HydrophobicContact CD-CZ2 4.26Å; K369-W371 HydrophobicContact CG-CD2 3.9Å; K369-W371 HydrophobicContact CG-CE3 4.25Å; K369-W371 HydrophobicContact CG-CG 4.38Å; K369-W371 HydrophobicContact CG-CH2 4.26Å; K369-W371 HydrophobicContact CG-CZ2 3.91Å; K369-W371 HydrophobicContact CG-CZ3 4.43Å; K369-W371 WeakPolarHBondContact CG-O 3.47Å; K369-W371 PolarHBondContact NZ-O 2.91Å; W371-Y380 WeakPolarHBondContact CA-OH 3.4Å; W371-R399 VanDerWaalsContact CE2-CZ 3.46Å; W371-R399 VanDerWaalsContact CE2-NH1 3.3Å; W371-L401 HydrophobicContact CB-CD1 4.4Å; W371-Q421 VanDerWaalsContact CE3-NE2 3.32Å
372P98.6Very high97Very high6 Ų663.1 Ų63.14%0.03934%0.335CS..PPolyproline II helixtrans-71.3160.6173.529-29.4000111.2A376 K378 V385 N387P372-A376 HydrophobicContact CB-CB 4.05Å; P372-A376 WeakPolarHBondContact CG-O 3.48Å; P372-K378 HydrophobicContact CB-CB 3.94Å; P372-K378 HydrophobicContact CG-CB 4.48Å; P372-V385 HydrophobicContact CG-CG1 4.32Å; P372-N387 HydrophobicContact CG-CB 3.83Å; P372-N387 PolarHBondContact O-ND2 2.96Å
373D98.6Very high97.3Very high105 Ų10554.9 Ų54.956%0.56131%0.305SS*.PPolyproline II helixtrans-61.4159.3171.3-59.6-41.4000111.1K369 Y375 A376 N387K369-D373 VanDerWaalsContact CE-OD1 3.26Å; K369-D373 WeakPolarHBondContact CE-OD1 3.45Å; K369-D373 IonicContact NZ-OD1 3.96Å; K369-D373 PolarHBondContact NZ-OD1 2.8Å; D373-Y375 PolarHBondContact O-N 3.49Å; D373-A376 HydrophobicContact CB-CB 4.4Å; D373-A376 VanDerWaalsContact O-CB 3.26Å; D373-A376 WeakPolarHBondContact O-CB 3.46Å; D373-A376 PolarHBondContact O-N 3.28Å; D373-N387 WeakPolarHBondContact O-CB 3.49Å
374E98.4Very high97.5Very high62 Ų6255.2 Ų55.229%0.2928%0.283SS..THydrogen-bonded Turntrans-50.5135.2179.2-163.2179.5-16000110.9A376 N387 K389 E390E374-A376 PolarHBondContact O-N 2.87Å; E374-A376 VanDerWaalsContact O-N 3.08Å; E374-N387 PolarHBondContact N-ND2 3.47Å; E374-K389 WeakPolarHBondContact OE1-CD 3.39Å; E374-K389 WeakPolarHBondContact OE1-CE 3.36Å; E374-K389 IonicContact OE1-NZ 2.78Å; E374-K389 PolarHBondContact OE1-NZ 2.79Å; E374-E390 HydrophobicContact CB-CG 3.97Å; E374-E390 HydrophobicContact CG-CB 4.32Å; E374-E390 HydrophobicContact CG-CG 3.94Å; E374-E390 PolarHBondContact OE1-N 3Å
375Y97.9Very high97.8Very high139 Ų13948.9 Ų48.955%0.54526%0.256SS..THydrogen-bonded Turntrans68.9-10.9-175-46.9-62000116.2D373 N387 V388 K389D373-Y375 PolarHBondContact O-N 3.49Å; Y375-N387 WeakPolarHBondContact CA-O 2.82Å; Y375-N387 PolarHBondContact N-O 2.78Å; Y375-V388 VanDerWaalsContact CD1-O 3.32Å; Y375-V388 WeakPolarHBondContact CD1-O 3.36Å; Y375-V388 WeakPolarHBondContact CE1-O 3.4Å; Y375-K389 HydrophobicContact CE1-CD 4.46Å; Y375-K389 PolarHBondContact OH-NZ 3.07Å
376A98.5Very high97.9Very high38 Ų3851.1 Ų51.131%0.31426%0.255SS..  trans-80.9155.3179.200000112.8P372 D373 E374 R386 N387P372-A376 HydrophobicContact CB-CB 4.05Å; P372-A376 WeakPolarHBondContact CG-O 3.48Å; D373-A376 HydrophobicContact CB-CB 4.4Å; D373-A376 VanDerWaalsContact O-CB 3.26Å; D373-A376 WeakPolarHBondContact O-CB 3.46Å; D373-A376 PolarHBondContact O-N 3.28Å; E374-A376 PolarHBondContact O-N 2.87Å; E374-A376 VanDerWaalsContact O-N 3.08Å; A376-R386 WeakPolarHBondContact O-CA 3.3Å; A376-N387 PolarHBondContact O-N 3Å
377L97.9Very high97.9Very high85 Ų8550.3 Ų50.345%0.44525%0.251SS..EExtended strand (participates in β ladder)trans-115.8134.8175.3-177.474.7000108.6R384 R386L377-R384 HydrophobicContact CD1-CG 3.66Å; L377-R384 HydrophobicContact CG-CG 4.21Å; L377-R386 HydrophobicContact CD1-CB 3.67Å; L377-R386 HydrophobicContact CD1-CG 4.41Å
378K98.3Very high98Very high105 Ų10552.2 Ų52.246%0.45726%0.263SS..EExtended strand (participates in β ladder)trans-141.6144.2175.4-173.2163.2169.7-1720111.6P372 Y380 V385P372-K378 HydrophobicContact CB-CB 3.94Å; P372-K378 HydrophobicContact CG-CB 4.48Å; K378-Y380 HydrophobicContact CB-CE2 4.05Å; K378-Y380 HydrophobicContact CD-CE1 3.83Å; K378-Y380 HydrophobicContact CD-CE2 4.48Å; K378-Y380 WeakPolarHBondContact CD-OH 3.32Å; K378-Y380 HydrophobicContact CG-CE1 4.03Å; K378-Y380 HydrophobicContact CG-CE2 4.11Å; K378-V385 PolarHBondContact N-O 3.43Å; K378-V385 PolarHBondContact O-N 3.35Å
379E98Very high98Very high100 Ų10055 Ų5547%0.46727%0.273SS..EExtended strand (participates in β ladder)trans-98.3137.3172.7-61.3-171.4161.100110M383 R384 V406E379-M383 CarbonylContact C-O 3.56Å; E379-M383 WeakPolarHBondContact CA-O 3.43Å; E379-R384 HydrophobicContact CG-CB 4.3Å; E379-R384 HydrophobicContact CG-CG 4.2Å; E379-R384 IonicContact OE1-CZ 3.63Å; E379-R384 VanDerWaalsContact OE1-CZ 3.3Å; E379-R384 IonicContact OE1-NE 3.32Å; E379-R384 PolarHBondContact OE1-NE 2.86Å; E379-R384 IonicContact OE1-NH2 2.9Å; E379-R384 PolarHBondContact OE1-NH2 2.81Å; E379-V406 HydrophobicContact CG-CG2 4.29Å
380Y97.4Very high98Very high9 Ų954 Ų544%0.03527%0.27CS..EExtended strand (participates in β ladder)trans-127.882.6-178.5-62.4-73.1000107.7V338 N339 W342 Y370 W371 K378 V382 M383 V385V338-Y380 HydrophobicContact CG1-CD1 3.33Å; V338-Y380 HydrophobicContact CG1-CE1 3.64Å; V338-Y380 HydrophobicContact CG1-CG 4.03Å; N339-Y380 VanDerWaalsContact OD1-C 3.27Å; N339-Y380 WeakPolarHBondContact OD1-CA 3.42Å; W342-Y380 AromaticContact CD1-CD2 3.56Å; W342-Y380 AromaticContact CD1-CG 3.64Å; W342-Y380 HydrophobicContact CG-CD2 4.42Å; W342-Y380 AromaticContact NE1-CD2 3.51Å; W342-Y380 AromaticContact NE1-CE2 3.7Å; W342-Y380 AromaticContact NE1-CG 3.94Å; Y370-Y380 WeakPolarHBondContact O-CE2 3.35Å; Y370-Y380 VanDerWaalsContact O-CZ 3.24Å; Y370-Y380 PolarHBondContact O-OH 2.78Å; W371-Y380 WeakPolarHBondContact CA-OH 3.4Å; K378-Y380 HydrophobicContact CB-CE2 4.05Å; K378-Y380 HydrophobicContact CD-CE1 3.83Å; K378-Y380 HydrophobicContact CD-CE2 4.48Å; K378-Y380 WeakPolarHBondContact CD-OH 3.32Å; K378-Y380 HydrophobicContact CG-CE1 4.03Å; K378-Y380 HydrophobicContact CG-CE2 4.11Å; Y380-V382 PolarHBondContact O-N 3.29Å; Y380-M383 PolarHBondContact N-O 3.16Å; Y380-M383 PolarHBondContact O-N 3Å; Y380-V385 HydrophobicContact CD2-CB 4.18Å; Y380-V385 HydrophobicContact CD2-CG2 3.89Å; Y380-V385 HydrophobicContact CE2-CB 3.99Å; Y380-V385 HydrophobicContact CE2-CG2 4.12Å
381G94.8Very high97.9Very high48 Ų4857 Ų5750%0.49529%0.29SS..THydrogen-bonded Turntrans61.6-127.5-166.900000110.6N339 M383N339-G381 PolarHBondContact OD1-N 2.71Å; G381-M383 PolarHBondContact O-N 2.95Å
382V94.5Very high97.9Very high73 Ų7360.9 Ų60.944%0.44232%0.323SS..THydrogen-bonded Turntrans-78.4-2.6179.1-59.60000114.2Y380 V406Y380-V382 PolarHBondContact O-N 3.29Å; V382-V406 PolarHBondContact O-N 2.73Å
383M97.3Very high97.7Very high7 Ų762.2 Ų62.23%0.03433%0.334CS..EExtended strand (participates in β ladder)trans-102.6137.7-178.4-61.6-56.4169.300110.8W342 R343 F346 E379 Y380 G381 L403 K405W342-M383 HydrophobicContact CB-CB 3.8Å; W342-M383 HydrophobicContact CB-CG 3.92Å; R343-M383 HydrophobicContact CG-CE 4.25Å; F346-M383 HydrophobicContact CB-CE 3.56Å; F346-M383 HydrophobicContact CB-SD 3.79Å; F346-M383 HydrophobicContact CD1-CE 3.69Å; F346-M383 HydrophobicContact CD1-SD 4.34Å; F346-M383 HydrophobicContact CD2-CE 4.36Å; F346-M383 HydrophobicContact CD2-SD 3.94Å; F346-M383 HydrophobicContact CE1-CE 4.49Å; F346-M383 HydrophobicContact CG-CE 3.6Å; F346-M383 HydrophobicContact CG-SD 3.75Å; E379-M383 CarbonylContact C-O 3.56Å; E379-M383 WeakPolarHBondContact CA-O 3.43Å; Y380-M383 PolarHBondContact N-O 3.16Å; Y380-M383 PolarHBondContact O-N 3Å; G381-M383 PolarHBondContact O-N 2.95Å; M383-L403 HydrophobicContact CB-CD1 4.13Å; M383-K405 HydrophobicContact SD-CB 4.44Å; M383-K405 HydrophobicContact SD-CG 4.43Å
384R97.6Very high97.5Very high79 Ų7964.8 Ų64.830%0.29834%0.343SS..EExtended strand (participates in β ladder)trans-117.1128.7177.6179.9-175-65.5154-2.6109.7L377 E379 L403 S404 V406L377-R384 HydrophobicContact CD1-CG 3.66Å; L377-R384 HydrophobicContact CG-CG 4.21Å; E379-R384 HydrophobicContact CG-CB 4.3Å; E379-R384 HydrophobicContact CG-CG 4.2Å; E379-R384 IonicContact OE1-CZ 3.63Å; E379-R384 VanDerWaalsContact OE1-CZ 3.3Å; E379-R384 IonicContact OE1-NE 3.32Å; E379-R384 PolarHBondContact OE1-NE 2.86Å; E379-R384 IonicContact OE1-NH2 2.9Å; E379-R384 PolarHBondContact OE1-NH2 2.81Å; R384-L403 WeakPolarHBondContact O-CA 3.45Å; R384-S404 PolarHBondContact N-O 3.49Å; R384-S404 PolarHBondContact O-N 2.87Å; R384-V406 HydrophobicContact CB-CG2 3.93Å
385V98.6Very high97.4Very high0 Ų063.6 Ų63.60%034%0.338CS..EExtended strand (participates in β ladder)trans-126128.3-178-176.20000110W342 P372 K378 Y380 L401 K402 L403W342-V385 HydrophobicContact CD2-CG2 3.72Å; W342-V385 HydrophobicContact CE3-CG2 3.97Å; W342-V385 HydrophobicContact CG-CG2 4.25Å; W342-V385 HydrophobicContact CH2-CG1 4.06Å; W342-V385 HydrophobicContact CH2-CG2 4.1Å; W342-V385 HydrophobicContact CZ2-CB 4.45Å; W342-V385 HydrophobicContact CZ2-CG1 3.98Å; W342-V385 HydrophobicContact CZ2-CG2 3.85Å; W342-V385 HydrophobicContact CZ3-CG2 4.15Å; P372-V385 HydrophobicContact CG-CG1 4.32Å; K378-V385 PolarHBondContact N-O 3.43Å; K378-V385 PolarHBondContact O-N 3.35Å; Y380-V385 HydrophobicContact CD2-CB 4.18Å; Y380-V385 HydrophobicContact CD2-CG2 3.89Å; Y380-V385 HydrophobicContact CE2-CB 3.99Å; Y380-V385 HydrophobicContact CE2-CG2 4.12Å; V385-L401 HydrophobicContact CG1-CB 4.21Å; V385-K402 CarbonylContact C-O 3.55Å; V385-K402 VanDerWaalsContact CA-O 3.28Å; V385-K402 WeakPolarHBondContact CA-O 3.45Å; V385-L403 HydrophobicContact CG2-CD1 3.78Å
386R98.6Very high97.4Very high105 Ų10558.8 Ų58.840%0.39632%0.32SS..EExtended strand (participates in β ladder)trans-108.4133.6168.1-178.4179.9-70-82.92.9109.1A376 L377 V388 L401 K402A376-R386 WeakPolarHBondContact O-CA 3.3Å; L377-R386 HydrophobicContact CD1-CB 3.67Å; L377-R386 HydrophobicContact CD1-CG 4.41Å; R386-V388 HydrophobicContact CG-CG2 4.41Å; R386-L401 CarbonylContact O-C 3.57Å; R386-L401 VanDerWaalsContact O-CA 3.27Å; R386-L401 WeakPolarHBondContact O-CA 3.25Å; R386-K402 HydrophobicContact CB-CB 4.27Å; R386-K402 PolarHBondContact N-O 3.09Å; R386-K402 PolarHBondContact O-N 2.71Å
387N98.8Very high97.4Very high0 Ų057.2 Ų57.20%031%0.306CS..EExtended strand (participates in β ladder)trans-90.5110.5166.7-176.5-6.8000107.7P372 D373 E374 Y375 A376 E390 L401P372-N387 HydrophobicContact CG-CB 3.83Å; P372-N387 PolarHBondContact O-ND2 2.96Å; D373-N387 WeakPolarHBondContact O-CB 3.49Å; E374-N387 PolarHBondContact N-ND2 3.47Å; Y375-N387 WeakPolarHBondContact CA-O 2.82Å; Y375-N387 PolarHBondContact N-O 2.78Å; A376-N387 PolarHBondContact O-N 3Å; N387-E390 PolarHBondContact ND2-OE1 2.96Å; N387-L401 HydrophobicContact CB-CD2 3.79Å
388V98.7Very high97.4Very high41 Ų4154.5 Ų54.525%0.24829%0.292CS..EExtended strand (participates in β ladder)trans-81-45.3-174.2178.90000110.2Y375 R386 E400 K402Y375-V388 VanDerWaalsContact CD1-O 3.32Å; Y375-V388 WeakPolarHBondContact CD1-O 3.36Å; Y375-V388 WeakPolarHBondContact CE1-O 3.4Å; R386-V388 HydrophobicContact CG-CG2 4.41Å; V388-E400 HydrophobicContact CB-CB 4.27Å; V388-E400 HydrophobicContact CB-CG 4.21Å; V388-E400 WeakPolarHBondContact CB-O 3.34Å; V388-E400 PolarHBondContact N-O 3.07Å; V388-K402 HydrophobicContact CG2-CB 4.34Å; V388-K402 HydrophobicContact CG2-CD 3.75Å; V388-K402 HydrophobicContact CG2-CG 3.73Å
389K98.5Very high97.5Very high84 Ų8450.4 Ų50.437%0.36527%0.273SS..EExtended strand (participates in β ladder)trans-159.3142.5-174.7-171.470.1-162132.90110.9E374 Y375 R399 E400E374-K389 WeakPolarHBondContact OE1-CD 3.39Å; E374-K389 WeakPolarHBondContact OE1-CE 3.36Å; E374-K389 IonicContact OE1-NZ 2.78Å; E374-K389 PolarHBondContact OE1-NZ 2.79Å; Y375-K389 HydrophobicContact CE1-CD 4.46Å; Y375-K389 PolarHBondContact OH-NZ 3.07Å; K389-R399 WeakPolarHBondContact O-CA 3.5Å; K389-E400 PolarHBondContact O-N 3.2Å
390E98.6Very high97.5Very high47 Ų4748.2 Ų48.222%0.2226%0.263CS..EExtended strand (participates in β ladder)trans-109.5136.1165.4-57.6-161.7-171.900110.6E374 N387 T397 L398 R399E374-E390 HydrophobicContact CB-CG 3.97Å; E374-E390 HydrophobicContact CG-CB 4.32Å; E374-E390 HydrophobicContact CG-CG 3.94Å; E374-E390 PolarHBondContact OE1-N 3Å; N387-E390 PolarHBondContact ND2-OE1 2.96Å; E390-T397 HydrophobicContact CB-CG2 4.46Å; E390-L398 CarbonylContact C-O 3.53Å; E390-L398 WeakPolarHBondContact CA-O 3.5Å; E390-R399 HydrophobicContact CG-CB 4.49Å; E390-R399 HydrophobicContact CG-CG 3.91Å; E390-R399 WeakPolarHBondContact OE1-CD 3.09Å; E390-R399 IonicContact OE1-NE 3.24Å; E390-R399 PolarHBondContact OE1-NE 3.3Å; E390-R399 IonicContact OE2-CZ 3.19Å; E390-R399 IonicContact OE2-NE 3.89Å; E390-R399 PolarHBondContact OE2-NE 3.19Å; E390-R399 IonicContact OE2-NH2 3.8Å; E390-R399 PolarHBondContact OE2-NH2 2.92Å
391S98.3Very high97.6Very high61 Ų6147.8 Ų47.843%0.42726%0.261SS..EExtended strand (participates in β ladder)trans-124.6115.5174.1-61.60000108.6L398S391-L398 PolarHBondContact N-O 2.76Å; S391-L398 PolarHBondContact O-N 3.37Å
392A97.1Very high97.8Very high84 Ų8448.4 Ų48.469%0.69425%0.251SS*.EExtended strand (participates in β ladder)trans-88.1122.6177.900000110.4
393A95.9Very high97.9Very high35 Ų3545 Ų4529%0.28923%0.23SC..  trans-100.2176.9163.200000109.6Y396 R425A393-Y396 CarbonylContact C-O 3.57Å; A393-Y396 WeakPolarHBondContact CA-O 3.36Å; A393-Y396 HydrophobicContact CB-CD1 3.78Å; A393-Y396 HydrophobicContact CB-CD2 4.29Å; A393-Y396 HydrophobicContact CB-CE1 3.58Å; A393-Y396 HydrophobicContact CB-CE2 4.09Å; A393-Y396 HydrophobicContact CB-CG 4.13Å; A393-Y396 PolarHBondContact N-O 3.35Å; A393-Y396 VanDerWaalsContact O-O 3.1Å; A393-R425 PolarHBondContact O-NH2 2.89Å
394H94.4Very high97.9Very high158 Ų15845.3 Ų45.373%0.73123%0.233SC*.SBendtrans-57.7-58.5176.6177.9-99.2000111.2
395D95.8Very high97.6Very high37 Ų3743.7 Ų43.720%0.19823%0.228CC..SBendtrans-89.5-19.5-173.4-68.5-68.4000114.8F424 R425 T426D395-F424 HydrophobicContact CB-CD2 4.37Å; D395-F424 HydrophobicContact CB-CE2 3.73Å; D395-F424 HydrophobicContact CB-CZ 4.11Å; D395-R425 PolarHBondContact O-N 3.37Å; D395-T426 HydrophobicContact CB-CG2 4.38Å; D395-T426 WeakPolarHBondContact CB-OG1 3.39Å; D395-T426 WeakPolarHBondContact OD1-CB 3.34Å; D395-T426 WeakPolarHBondContact OD1-CG2 3.48Å; D395-T426 PolarHBondContact OD1-OG1 3.31Å
396Y98Very high97.2Very high39 Ų3946 Ų4615%0.15324%0.242CC..EExtended strand (participates in β ladder)trans-143.5167.2-172.770.3-88.3000113.5A393 L398 Y422 H423 F442A393-Y396 CarbonylContact C-O 3.57Å; A393-Y396 WeakPolarHBondContact CA-O 3.36Å; A393-Y396 HydrophobicContact CB-CD1 3.78Å; A393-Y396 HydrophobicContact CB-CD2 4.29Å; A393-Y396 HydrophobicContact CB-CE1 3.58Å; A393-Y396 HydrophobicContact CB-CE2 4.09Å; A393-Y396 HydrophobicContact CB-CG 4.13Å; A393-Y396 PolarHBondContact N-O 3.35Å; A393-Y396 VanDerWaalsContact O-O 3.1Å; Y396-L398 HydrophobicContact CE2-CB 4.17Å; Y396-Y422 HydrophobicContact CD2-CD1 4.19Å; Y396-Y422 HydrophobicContact CE2-CD1 4.02Å; Y396-Y422 HydrophobicContact CE2-CE1 4.16Å; Y396-H423 CarbonylContact C-O 3.58Å; Y396-H423 WeakPolarHBondContact CA-O 3.34Å; Y396-H423 WeakPolarHBondContact CB-O 3.44Å; Y396-F442 HydrophobicContact CD1-CB 4.38Å; Y396-F442 AromaticContact CD1-CD2 3.56Å; Y396-F442 HydrophobicContact CD1-CD2 3.56Å; Y396-F442 HydrophobicContact CD1-CE2 4.32Å; Y396-F442 HydrophobicContact CD1-CG 4.43Å; Y396-F442 AromaticContact CD2-CD2 4Å; Y396-F442 HydrophobicContact CD2-CD2 4Å; Y396-F442 HydrophobicContact CD2-CE2 4.03Å; Y396-F442 HydrophobicContact CE1-CD2 4.14Å; Y396-F442 AromaticContact CG-CD2 3.47Å; Y396-F442 HydrophobicContact CG-CD2 3.47Å; Y396-F442 VanDerWaalsContact CG-CD2 3.47Å; Y396-F442 AromaticContact CG-CE2 3.77Å; Y396-F442 HydrophobicContact CG-CE2 3.77Å
397T98.6Very high96.3Very high5 Ų543.4 Ų43.43%0.03125%0.248CC..EExtended strand (participates in β ladder)trans-117.7127.6167.2-58.60000108.7E390 R399 H423 R425E390-T397 HydrophobicContact CB-CG2 4.46Å; T397-R399 HydrophobicContact CG2-CG 4.27Å; T397-H423 PolarHBondContact N-O 2.87Å; T397-H423 PolarHBondContact O-N 3.2Å; T397-R425 WeakPolarHBondContact OG1-CD 3.33Å; T397-R425 PolarHBondContact OG1-NE 3.22Å; T397-R425 VanDerWaalsContact OG1-NE 3.13Å; T397-R425 PolarHBondContact OG1-NH1 3.46Å
398L98.8Very high94.9Very high28 Ų2845.4 Ų45.415%0.14726%0.257CS..EExtended strand (participates in β ladder)trans-93.6132.9170.2177.560.7000109.2E390 S391 Y396 W420 Q421 Y422E390-L398 CarbonylContact C-O 3.53Å; E390-L398 WeakPolarHBondContact CA-O 3.5Å; S391-L398 PolarHBondContact N-O 2.76Å; S391-L398 PolarHBondContact O-N 3.37Å; Y396-L398 HydrophobicContact CE2-CB 4.17Å; L398-W420 HydrophobicContact CD1-CB 4.36Å; L398-W420 HydrophobicContact CD1-CE3 4.05Å; L398-W420 HydrophobicContact CD2-CE3 4.23Å; L398-W420 HydrophobicContact CD2-CZ3 4.36Å; L398-W420 HydrophobicContact CG-CE3 4.34Å; L398-Q421 CarbonylContact C-O 3.58Å; L398-Q421 WeakPolarHBondContact CA-O 3.43Å; L398-Y422 HydrophobicContact CD1-CD1 4.07Å; L398-Y422 HydrophobicContact CD1-CD2 3.83Å; L398-Y422 HydrophobicContact CD1-CE1 3.85Å; L398-Y422 HydrophobicContact CD1-CE2 3.59Å; L398-Y422 HydrophobicContact CD1-CG 4.07Å
399R98.8Very high93Very high18 Ų1847.3 Ų47.37%0.06828%0.278CS..EExtended strand (participates in β ladder)trans-121.5127.3170.1-47.1-163.7173.189.4-2.3110.4W371 K389 E390 T397 L401 Q421 H423W371-R399 VanDerWaalsContact CE2-CZ 3.46Å; W371-R399 VanDerWaalsContact CE2-NH1 3.3Å; K389-R399 WeakPolarHBondContact O-CA 3.5Å; E390-R399 HydrophobicContact CG-CB 4.49Å; E390-R399 HydrophobicContact CG-CG 3.91Å; E390-R399 WeakPolarHBondContact OE1-CD 3.09Å; E390-R399 IonicContact OE1-NE 3.24Å; E390-R399 PolarHBondContact OE1-NE 3.3Å; E390-R399 IonicContact OE2-CZ 3.19Å; E390-R399 IonicContact OE2-NE 3.89Å; E390-R399 PolarHBondContact OE2-NE 3.19Å; E390-R399 IonicContact OE2-NH2 3.8Å; E390-R399 PolarHBondContact OE2-NH2 2.92Å; T397-R399 HydrophobicContact CG2-CG 4.27Å; R399-L401 HydrophobicContact CB-CD2 3.91Å; R399-L401 HydrophobicContact CB-CG 4.25Å; R399-Q421 HydrophobicContact CB-CB 4.24Å; R399-Q421 PolarHBondContact N-O 3.43Å; R399-Q421 PolarHBondContact O-N 3.39Å; R399-H423 PolarHBondContact NH1-ND1 3.35Å
400E98.8Very high90.9Very high54 Ų5451 Ų5125%0.25230%0.3SS..EExtended strand (participates in β ladder)trans-87.2110.2169.3-173.7-175.4158.600108.6V388 K389 T418 W420V388-E400 HydrophobicContact CB-CB 4.27Å; V388-E400 HydrophobicContact CB-CG 4.21Å; V388-E400 WeakPolarHBondContact CB-O 3.34Å; V388-E400 PolarHBondContact N-O 3.07Å; K389-E400 PolarHBondContact O-N 3.2Å; E400-T418 HydrophobicContact CG-CG2 3.66Å; E400-W420 HydrophobicContact CB-CE3 4.19Å; E400-W420 HydrophobicContact CB-CH2 4.37Å; E400-W420 HydrophobicContact CB-CZ3 3.85Å; E400-W420 HydrophobicContact CG-CE3 4.29Å; E400-W420 HydrophobicContact CG-CH2 3.89Å; E400-W420 HydrophobicContact CG-CZ2 4.34Å; E400-W420 HydrophobicContact CG-CZ3 3.86Å
401L98.8Very high88.9Confident0 Ų056 Ų560%033%0.327CS..EExtended strand (participates in β ladder)trans-110.2140.4-178.6-50.4178.3000109.9W342 W371 V385 R386 N387 R399 T418 V419 Q421W342-L401 HydrophobicContact CH2-CD1 3.74Å; W342-L401 HydrophobicContact CZ2-CD1 4.33Å; W371-L401 HydrophobicContact CB-CD1 4.4Å; V385-L401 HydrophobicContact CG1-CB 4.21Å; R386-L401 CarbonylContact O-C 3.57Å; R386-L401 VanDerWaalsContact O-CA 3.27Å; R386-L401 WeakPolarHBondContact O-CA 3.25Å; N387-L401 HydrophobicContact CB-CD2 3.79Å; R399-L401 HydrophobicContact CB-CD2 3.91Å; R399-L401 HydrophobicContact CB-CG 4.25Å; L401-T418 CarbonylContact O-C 3.58Å; L401-T418 VanDerWaalsContact O-CA 3.29Å; L401-T418 WeakPolarHBondContact O-CA 3.39Å; L401-V419 WeakPolarHBondContact CA-O 3.4Å; L401-V419 HydrophobicContact CB-CB 4.44Å; L401-V419 VanDerWaalsContact CB-O 3.28Å; L401-V419 WeakPolarHBondContact CB-O 3.14Å; L401-V419 PolarHBondContact N-O 2.91Å; L401-V419 PolarHBondContact O-N 3.33Å; L401-Q421 HydrophobicContact CD1-CB 3.95Å
402K98.5Very high86.8Confident62 Ų6260.1 Ų60.127%0.2734%0.34SS..EExtended strand (participates in β ladder)trans-105.6118.7168.3-76.9178.3162.3-141.80109.5V385 R386 V388 E416V385-K402 CarbonylContact C-O 3.55Å; V385-K402 VanDerWaalsContact CA-O 3.28Å; V385-K402 WeakPolarHBondContact CA-O 3.45Å; R386-K402 HydrophobicContact CB-CB 4.27Å; R386-K402 PolarHBondContact N-O 3.09Å; R386-K402 PolarHBondContact O-N 2.71Å; V388-K402 HydrophobicContact CG2-CB 4.34Å; V388-K402 HydrophobicContact CG2-CD 3.75Å; V388-K402 HydrophobicContact CG2-CG 3.73Å; K402-E416 HydrophobicContact CB-CG 4.16Å; K402-E416 HydrophobicContact CD-CG 4.46Å; K402-E416 HydrophobicContact CG-CG 4.41Å; K402-E416 IonicContact NZ-OE2 2.66Å; K402-E416 PolarHBondContact NZ-OE2 2.9Å
403L98.3Very high85Confident0 Ų058.1 Ų58.10%033%0.327CS..EExtended strand (participates in β ladder)trans-107.5132.5179.7172.864.8000109.6W342 V345 F346 M383 R384 V385 E416 R417 V419W342-L403 HydrophobicContact CE3-CD1 3.87Å; W342-L403 HydrophobicContact CE3-CD2 4.06Å; W342-L403 HydrophobicContact CE3-CG 4.5Å; W342-L403 HydrophobicContact CZ3-CD1 4.41Å; W342-L403 HydrophobicContact CZ3-CD2 4.29Å; V345-L403 HydrophobicContact CB-CD2 4.42Å; V345-L403 HydrophobicContact CG1-CD2 3.76Å; F346-L403 HydrophobicContact CB-CD2 4.09Å; F346-L403 HydrophobicContact CD2-CD2 4.08Å; F346-L403 HydrophobicContact CD2-CG 4.09Å; M383-L403 HydrophobicContact CB-CD1 4.13Å; R384-L403 WeakPolarHBondContact O-CA 3.45Å; V385-L403 HydrophobicContact CG2-CD1 3.78Å; L403-E416 CarbonylContact O-C 3.58Å; L403-E416 VanDerWaalsContact O-CA 3.3Å; L403-E416 WeakPolarHBondContact O-CA 3.43Å; L403-R417 PolarHBondContact N-O 3.33Å; L403-R417 PolarHBondContact O-N 3.44Å; L403-V419 HydrophobicContact CB-CG2 3.95Å; L403-V419 HydrophobicContact CD2-CG2 4.1Å
404S95.7Very high83.9Confident15 Ų1562.5 Ų62.511%0.10535%0.346CS..EExtended strand (participates in β ladder)trans-146.1161.3174.856.70000110.9R384R384-S404 PolarHBondContact N-O 3.49Å; R384-S404 PolarHBondContact O-N 2.87Å
405K92.8Very high83.5Confident44 Ų4456.5 Ų56.519%0.19132%0.321CS..EExtended strand (participates in β ladder)trans-90.9130.5173-165.8167.9179.5177.70110D294 F346 M383 G407 Q408 T415D294-K405 IonicContact OD2-NZ 2.94Å; F346-K405 HydrophobicContact CE1-CD 4.27Å; F346-K405 HydrophobicContact CE2-CB 4.2Å; F346-K405 HydrophobicContact CZ-CB 3.99Å; F346-K405 HydrophobicContact CZ-CD 4.46Å; M383-K405 HydrophobicContact SD-CB 4.44Å; M383-K405 HydrophobicContact SD-CG 4.43Å; K405-G407 PolarHBondContact O-N 3.34Å; K405-Q408 HydrophobicContact CB-CG 4.27Å; K405-Q408 HydrophobicContact CD-CG 4.22Å; K405-Q408 HydrophobicContact CG-CG 4.21Å; K405-T415 PolarHBondContact N-OG1 2.93Å
406V90.2Very high83.4Confident50 Ų5058.3 Ų58.330%0.30333%0.328SS..THydrogen-bonded Turntrans-59.8136.7-179.9177.70000109.9E379 V382 R384 Q408E379-V406 HydrophobicContact CG-CG2 4.29Å; V382-V406 PolarHBondContact O-N 2.73Å; R384-V406 HydrophobicContact CB-CG2 3.93Å; V406-Q408 VanDerWaalsContact C-N 3.29Å; V406-Q408 PolarHBondContact O-N 3.01Å
407G78.3Confident83.3Confident50 Ų5058 Ų5852%0.51533%0.326SS..THydrogen-bonded Turntrans78.3-6.5173.200000116.7K405K405-G407 PolarHBondContact O-N 3.34Å
408Q69.9Low83.3Confident41 Ų4159.7 Ų59.719%0.19234%0.337CS..G310 helixtrans-85.1-13.3-176.1-76.3-151.6-30.900116.1K405 V406 L410 L411 Q412 T415K405-Q408 HydrophobicContact CB-CG 4.27Å; K405-Q408 HydrophobicContact CD-CG 4.22Å; K405-Q408 HydrophobicContact CG-CG 4.21Å; V406-Q408 VanDerWaalsContact C-N 3.29Å; V406-Q408 PolarHBondContact O-N 3.01Å; Q408-L410 PolarHBondContact O-N 3.15Å; Q408-L411 PolarHBondContact O-N 2.72Å; Q408-L411 VanDerWaalsContact O-N 3.17Å; Q408-Q412 PolarHBondContact O-N 3.45Å; Q408-T415 HydrophobicContact CB-CG2 4.34Å
409A59.4Low83.3Confident82 Ų8258.4 Ų58.468%0.67833%0.33SS*.G310 helixtrans-57.6-21.3178.500000113.7
410L54.8Low83.3Confident161 Ų16159.7 Ų59.784%0.84334%0.335SS*.G310 helixtrans-94.6-13.5-176.4-66.9168.9000114.5Q408Q408-L410 PolarHBondContact O-N 3.15Å
411L55.9Low83.3Confident151 Ų15157.1 Ų57.179%0.79132%0.323SS*.THydrogen-bonded Turntrans-124.1-31.6-167.7-67.3169.6000115.2Q408Q408-L411 PolarHBondContact O-N 2.72Å; Q408-L411 VanDerWaalsContact O-N 3.17Å
412Q53.7Low83.3Confident149 Ų14957.2 Ų57.270%0.69632%0.324SS*.SBendtrans-139.217-170.5-78.4172.8-11.600114.4Q408Q408-Q412 PolarHBondContact O-N 3.45Å
413G58.8Low83.3Confident41 Ų4154.8 Ų54.842%0.42331%0.313SS..  trans88.1177.9-177.100000113.7T415G413-T415 PolarHBondContact O-N 2.89Å
414N73.9Confident83.3Confident127 Ų12755 Ų5568%0.67931%0.314SS*.  trans-74.7110.2-177.6-170.711.1000110.5E416N414-E416 VanDerWaalsContact C-N 3.27Å; N414-E416 WeakPolarHBondContact OD1-CB 3.33Å; N414-E416 PolarHBondContact OD1-N 3.01Å; N414-E416 VanDerWaalsContact OD1-N 3.07Å
415T84.8Confident83.3Confident33 Ų3358.6 Ų58.620%0.20233%0.325CS..  trans-87.76.3174.759.30000113.4K405 Q408 G413 R417K405-T415 PolarHBondContact N-OG1 2.93Å; Q408-T415 HydrophobicContact CB-CG2 4.34Å; G413-T415 PolarHBondContact O-N 2.89Å; T415-R417 PolarHBondContact O-N 2.91Å
416E93.8Very high83.4Confident75 Ų7559.4 Ų59.435%0.3533%0.334SS..  trans-64.4133.7176.4-171.3178-103.100111K402 L403 N414K402-E416 HydrophobicContact CB-CG 4.16Å; K402-E416 HydrophobicContact CD-CG 4.46Å; K402-E416 HydrophobicContact CG-CG 4.41Å; K402-E416 IonicContact NZ-OE2 2.66Å; K402-E416 PolarHBondContact NZ-OE2 2.9Å; L403-E416 CarbonylContact O-C 3.58Å; L403-E416 VanDerWaalsContact O-CA 3.3Å; L403-E416 WeakPolarHBondContact O-CA 3.43Å; N414-E416 VanDerWaalsContact C-N 3.27Å; N414-E416 WeakPolarHBondContact OD1-CB 3.33Å; N414-E416 PolarHBondContact OD1-N 3.01Å; N414-E416 VanDerWaalsContact OD1-N 3.07Å
417R96.4Very high83.6Confident31 Ų3157.2 Ų57.212%0.11732%0.32CS..EExtended strand (participates in β ladder)trans-144.9152.7171.271-165.7-160.3-152.79.6111.5V345 F346 S350 L403 T415 V419V345-R417 VanDerWaalsContact C-NH2 3.26Å; V345-R417 PolarHBondContact O-NH2 3.19Å; F346-R417 PolarHBondContact O-NH1 3.46Å; F346-R417 PolarHBondContact O-NH2 2.92Å; S350-R417 PolarHBondContact O-NH2 2.72Å; L403-R417 PolarHBondContact N-O 3.33Å; L403-R417 PolarHBondContact O-N 3.44Å; T415-R417 PolarHBondContact O-N 2.91Å; R417-V419 HydrophobicContact CG-CG2 4.47Å
418T98.6Very high84.2Confident42 Ų4256.9 Ų56.926%0.25831%0.309SS..EExtended strand (participates in β ladder)trans-81.1133.5175.3-51.90000110.6E400 L401 W420E400-T418 HydrophobicContact CG-CG2 3.66Å; L401-T418 CarbonylContact O-C 3.58Å; L401-T418 VanDerWaalsContact O-CA 3.29Å; L401-T418 WeakPolarHBondContact O-CA 3.39Å; T418-W420 HydrophobicContact CG2-CD2 4.26Å; T418-W420 HydrophobicContact CG2-CZ2 3.92Å
419V98.9Very high84.4Confident0 Ų057.5 Ų57.50%031%0.314CS..EExtended strand (participates in β ladder)trans-121.9122.3172.8-179.30000107.8V345 R351 I353 L401 L403 R417V345-V419 HydrophobicContact CG1-CG1 4.37Å; V345-V419 HydrophobicContact CG1-CG2 4.24Å; R351-V419 CarbonylContact O-C 3.51Å; R351-V419 WeakPolarHBondContact O-CA 3.4Å; I353-V419 HydrophobicContact CD1-CG1 3.55Å; I353-V419 HydrophobicContact CG1-CG1 3.8Å; L401-V419 WeakPolarHBondContact CA-O 3.4Å; L401-V419 HydrophobicContact CB-CB 4.44Å; L401-V419 VanDerWaalsContact CB-O 3.28Å; L401-V419 WeakPolarHBondContact CB-O 3.14Å; L401-V419 PolarHBondContact N-O 2.91Å; L401-V419 PolarHBondContact O-N 3.33Å; L403-V419 HydrophobicContact CB-CG2 3.95Å; L403-V419 HydrophobicContact CD2-CG2 4.1Å; R417-V419 HydrophobicContact CG-CG2 4.47Å
420W98.9Very high85.3Confident45 Ų4558 Ų5817%0.1730%0.302CS..EExtended strand (participates in β ladder)trans-95.3112.3-178.6-59.388.2000109.4R351 V352 I353 L398 E400 T418 Y422 K449R351-W420 PolarHBondContact O-N 3.09Å; V352-W420 WeakPolarHBondContact CA-O 3.45Å; I353-W420 PolarHBondContact N-O 3.39Å; L398-W420 HydrophobicContact CD1-CB 4.36Å; L398-W420 HydrophobicContact CD1-CE3 4.05Å; L398-W420 HydrophobicContact CD2-CE3 4.23Å; L398-W420 HydrophobicContact CD2-CZ3 4.36Å; L398-W420 HydrophobicContact CG-CE3 4.34Å; E400-W420 HydrophobicContact CB-CE3 4.19Å; E400-W420 HydrophobicContact CB-CH2 4.37Å; E400-W420 HydrophobicContact CB-CZ3 3.85Å; E400-W420 HydrophobicContact CG-CE3 4.29Å; E400-W420 HydrophobicContact CG-CH2 3.89Å; E400-W420 HydrophobicContact CG-CZ2 4.34Å; E400-W420 HydrophobicContact CG-CZ3 3.86Å; T418-W420 HydrophobicContact CG2-CD2 4.26Å; T418-W420 HydrophobicContact CG2-CZ2 3.92Å; W420-Y422 HydrophobicContact CB-CD2 4.3Å; W420-Y422 HydrophobicContact CB-CE2 3.85Å; W420-K449 HydrophobicContact CB-CG 4.13Å; W420-K449 HydrophobicContact CD2-CD 3.91Å; W420-K449 HydrophobicContact CD2-CG 4.41Å; W420-K449 HydrophobicContact CG-CD 3.82Å; W420-K449 HydrophobicContact CG-CG 3.88Å
421Q98.9Very high86.9Confident0 Ų051.4 Ų51.40%027%0.273CS..EExtended strand (participates in β ladder)trans-96.1116.3176.3-171.4-14626.800110.1I353 Y370 W371 L398 R399 L401I353-Q421 HydrophobicContact CB-CB 4.47Å; I353-Q421 HydrophobicContact CB-CG 4.25Å; I353-Q421 HydrophobicContact CG2-CG 4.29Å; I353-Q421 CarbonylContact O-C 3.58Å; I353-Q421 WeakPolarHBondContact O-CA 3.11Å; Y370-Q421 PolarHBondContact OH-NE2 3.01Å; W371-Q421 VanDerWaalsContact CE3-NE2 3.32Å; L398-Q421 CarbonylContact C-O 3.58Å; L398-Q421 WeakPolarHBondContact CA-O 3.43Å; R399-Q421 HydrophobicContact CB-CB 4.24Å; R399-Q421 PolarHBondContact N-O 3.43Å; R399-Q421 PolarHBondContact O-N 3.39Å; L401-Q421 HydrophobicContact CD1-CB 3.95Å
422Y98.9Very high88.7Confident3 Ų346 Ų461%0.01225%0.246CC..EExtended strand (participates in β ladder)trans-99.6107.6174.3-78.4-94.7000109.3V352 I353 V354 M355 Y396 L398 W420 F442 E445 V446 K449V352-Y422 HydrophobicContact CG1-CD2 3.83Å; V352-Y422 HydrophobicContact CG1-CE2 4.14Å; I353-Y422 PolarHBondContact O-N 3.22Å; V354-Y422 CarbonylContact C-O 3.57Å; V354-Y422 WeakPolarHBondContact CA-O 3.23Å; M355-Y422 PolarHBondContact N-O 2.98Å; Y396-Y422 HydrophobicContact CD2-CD1 4.19Å; Y396-Y422 HydrophobicContact CE2-CD1 4.02Å; Y396-Y422 HydrophobicContact CE2-CE1 4.16Å; L398-Y422 HydrophobicContact CD1-CD1 4.07Å; L398-Y422 HydrophobicContact CD1-CD2 3.83Å; L398-Y422 HydrophobicContact CD1-CE1 3.85Å; L398-Y422 HydrophobicContact CD1-CE2 3.59Å; L398-Y422 HydrophobicContact CD1-CG 4.07Å; W420-Y422 HydrophobicContact CB-CD2 4.3Å; W420-Y422 HydrophobicContact CB-CE2 3.85Å; Y422-F442 HydrophobicContact CD1-CD2 4.25Å; Y422-F442 AromaticContact CD1-CE2 3.82Å; Y422-F442 HydrophobicContact CD1-CE2 3.82Å; Y422-F442 HydrophobicContact CG-CE2 4.15Å; Y422-E445 HydrophobicContact CE1-CB 4.02Å; Y422-E445 PolarHBondContact OH-O 3.32Å; Y422-V446 HydrophobicContact CD1-CG2 3.71Å; Y422-V446 HydrophobicContact CD2-CG2 3.97Å; Y422-V446 HydrophobicContact CE1-CG2 4.15Å; Y422-V446 HydrophobicContact CE2-CG2 4.39Å; Y422-V446 HydrophobicContact CG-CG2 3.6Å; Y422-K449 HydrophobicContact CE2-CB 4.17Å; Y422-K449 HydrophobicContact CE2-CG 4.06Å; Y422-K449 WeakPolarHBondContact OH-CB 3.28Å
423H98.8Very high90.6Very high11 Ų1139.8 Ų39.85%0.05122%0.219CC..EExtended strand (participates in β ladder)trans-109.3100.4-177.5178.7-165.4000110.6M355 T357 Y396 T397 R399 R425M355-H423 HydrophobicContact CB-CB 4.33Å; M355-H423 CarbonylContact O-C 3.54Å; T357-H423 PolarHBondContact O-NE2 3.49Å; Y396-H423 CarbonylContact C-O 3.58Å; Y396-H423 WeakPolarHBondContact CA-O 3.34Å; Y396-H423 WeakPolarHBondContact CB-O 3.44Å; T397-H423 PolarHBondContact N-O 2.87Å; T397-H423 PolarHBondContact O-N 3.2Å; R399-H423 PolarHBondContact NH1-ND1 3.35Å; H423-R425 WeakPolarHBondContact O-CG 3.33Å
424F98.2Very high92Very high5 Ų544.3 Ų44.32%0.02224%0.244CC..EExtended strand (participates in β ladder)trans-76.1126.4176.9-163.8-92.1000110.8M355 D395 T426 W427 V439 F442M355-F424 PolarHBondContact O-N 2.82Å; D395-F424 HydrophobicContact CB-CD2 4.37Å; D395-F424 HydrophobicContact CB-CE2 3.73Å; D395-F424 HydrophobicContact CB-CZ 4.11Å; F424-T426 WeakPolarHBondContact CE1-OG1 3.34Å; F424-T426 VanDerWaalsContact CZ-OG1 3.32Å; F424-T426 WeakPolarHBondContact CZ-OG1 3.27Å; F424-W427 HydrophobicContact CD1-CB 3.95Å; F424-W427 HydrophobicContact CD1-CE3 4.41Å; F424-W427 HydrophobicContact CE1-CB 4.02Å; F424-W427 HydrophobicContact CE1-CE3 4.32Å; F424-V439 HydrophobicContact CE1-CG2 4.26Å; F424-V439 HydrophobicContact CE2-CG2 4.22Å; F424-V439 HydrophobicContact CZ-CG2 3.72Å; F424-F442 HydrophobicContact CB-CE1 4.06Å; F424-F442 HydrophobicContact CB-CE2 4.26Å; F424-F442 HydrophobicContact CB-CZ 3.91Å; F424-F442 HydrophobicContact CD2-CB 3.99Å; F424-F442 AromaticContact CD2-CD1 3.74Å; F424-F442 HydrophobicContact CD2-CD1 3.74Å; F424-F442 AromaticContact CD2-CD2 3.96Å; F424-F442 HydrophobicContact CD2-CD2 3.96Å; F424-F442 HydrophobicContact CD2-CE1 4.14Å; F424-F442 HydrophobicContact CD2-CE2 4.29Å; F424-F442 AromaticContact CD2-CG 3.63Å; F424-F442 HydrophobicContact CD2-CG 3.63Å; F424-F442 HydrophobicContact CD2-CZ 4.38Å; F424-F442 HydrophobicContact CE2-CB 4.04Å; F424-F442 HydrophobicContact CE2-CD1 4.42Å; F424-F442 HydrophobicContact CE2-CG 4.2Å; F424-F442 HydrophobicContact CG-CD1 4.47Å; F424-F442 HydrophobicContact CG-CE1 4.48Å
425R96Very high92.8Very high89 Ų8942.4 Ų42.434%0.33623%0.234SC..  trans-115.7-14-167.3-60.5-177.4-61.4178.6-0.5114.2K358 A393 D395 T397 H423K358-R425 WeakPolarHBondContact CE-O 3.45Å; K358-R425 PolarHBondContact NZ-O 3.3Å; K358-R425 VanDerWaalsContact NZ-O 3.15Å; A393-R425 PolarHBondContact O-NH2 2.89Å; D395-R425 PolarHBondContact O-N 3.37Å; T397-R425 WeakPolarHBondContact OG1-CD 3.33Å; T397-R425 PolarHBondContact OG1-NE 3.22Å; T397-R425 VanDerWaalsContact OG1-NE 3.13Å; T397-R425 PolarHBondContact OG1-NH1 3.46Å; H423-R425 WeakPolarHBondContact O-CG 3.33Å
426T95.4Very high93.3Very high61 Ų6141.3 Ų41.337%0.37423%0.227SC..  trans-100.35.8-173.752.80000113.7D395 F424D395-T426 HydrophobicContact CB-CG2 4.38Å; D395-T426 WeakPolarHBondContact CB-OG1 3.39Å; D395-T426 WeakPolarHBondContact OD1-CB 3.34Å; D395-T426 WeakPolarHBondContact OD1-CG2 3.48Å; D395-T426 PolarHBondContact OD1-OG1 3.31Å; F424-T426 WeakPolarHBondContact CE1-OG1 3.34Å; F424-T426 VanDerWaalsContact CZ-OG1 3.32Å; F424-T426 WeakPolarHBondContact CZ-OG1 3.27Å
427W94.4Very high93.4Very high5 Ų538.1 Ų38.12%0.01921%0.214CC..  trans-64.8129171-159.4-66.7000109.7F424 G431 V432 P433 V439 R469 T472 F517F424-W427 HydrophobicContact CD1-CB 3.95Å; F424-W427 HydrophobicContact CD1-CE3 4.41Å; F424-W427 HydrophobicContact CE1-CB 4.02Å; F424-W427 HydrophobicContact CE1-CE3 4.32Å; W427-G431 PolarHBondContact NE1-O 3.49Å; W427-V432 HydrophobicContact CZ2-CG1 4.38Å; W427-P433 HydrophobicContact CD2-CG 4.17Å; W427-P433 HydrophobicContact CE3-CG 4.21Å; W427-V439 HydrophobicContact CZ3-CG2 4.3Å; W427-R469 VanDerWaalsContact CD1-CD 3.47Å; W427-R469 HydrophobicContact CD2-CG 4.13Å; W427-R469 HydrophobicContact CG-CG 4.42Å; W427-R469 HydrophobicContact CH2-CB 4.48Å; W427-R469 HydrophobicContact CZ2-CB 4.24Å; W427-R469 HydrophobicContact CZ2-CG 3.96Å; W427-T472 HydrophobicContact CH2-CG2 3.87Å; W427-F517 HydrophobicContact CH2-CE1 4.3Å
428P90.2Very high93.2Very high43 Ų4337.4 Ų37.428%0.27922%0.217SC..  trans-70.7148.3-177.827.5-34.4000112.6H430 V432 R469P428-H430 PolarHBondContact O-N 2.93Å; P428-H430 VanDerWaalsContact O-N 3.12Å; P428-V432 VanDerWaalsContact CG-C 3.41Å; P428-V432 WeakPolarHBondContact CG-O 3.26Å; P428-R469 PolarHBondContact O-NH2 2.7Å
429D72.9Confident93.1Very high54 Ų5435.6 Ų35.629%0.28921%0.206SC..SBendtrans-56.6-33.8-179-67.4-4.5000112.7R362 R469R362-D429 HydrophobicContact CG-CB 4.11Å; R362-D429 WeakPolarHBondContact CG-OD2 3.46Å; D429-R469 PolarHBondContact O-NH2 3.24Å
430H78.8Confident93Very high91 Ų9136 Ų3642%0.42121%0.208SC..SBendtrans-124.3140.8174-64.8-48.3000111T59 R362 P428T59-H430 WeakPolarHBondContact CB-ND1 3.44Å; T59-H430 WeakPolarHBondContact CG2-ND1 3.49Å; R362-H430 PolarHBondContact NH1-NE2 3.19Å; P428-H430 PolarHBondContact O-N 2.93Å; P428-H430 VanDerWaalsContact O-N 3.12Å
431G88.8Confident92.9Very high24 Ų2439.1 Ų39.125%0.24723%0.228CC..SBendtrans77.3-138.3176.500000113.3T59 W427T59-G431 PolarHBondContact O-N 3.1Å; W427-G431 PolarHBondContact NE1-O 3.49Å
432V93.4Very high92.8Very high37 Ų3739.2 Ų39.222%0.22423%0.228CC..  trans-135.3156.1-170.6-64.40000110.5W427 P428 A513 Q514 F517W427-V432 HydrophobicContact CZ2-CG1 4.38Å; P428-V432 VanDerWaalsContact CG-C 3.41Å; P428-V432 WeakPolarHBondContact CG-O 3.26Å; V432-A513 HydrophobicContact CG1-CB 4.39Å; V432-A513 HydrophobicContact CG2-CB 4.44Å; V432-Q514 HydrophobicContact CG1-CB 4.29Å; V432-Q514 HydrophobicContact CG1-CG 3.71Å; V432-F517 HydrophobicContact CB-CB 3.99Å; V432-F517 HydrophobicContact CB-CD2 3.89Å; V432-F517 HydrophobicContact CB-CG 3.93Å; V432-F517 HydrophobicContact CG1-CB 3.85Å; V432-F517 HydrophobicContact CG1-CG 4.16Å; V432-F517 HydrophobicContact CG2-CB 4.09Å; V432-F517 HydrophobicContact CG2-CD2 4.03Å; V432-F517 HydrophobicContact CG2-CG 4.3Å
433P93.9Very high92.7Very high18 Ų1839 Ų3912%0.11723%0.228CC..  trans-51.3142.3168.9-25.235.3000111.4W427 D435 V439 F517W427-P433 HydrophobicContact CD2-CG 4.17Å; W427-P433 HydrophobicContact CE3-CG 4.21Å; P433-D435 PolarHBondContact O-N 2.86Å; P433-V439 HydrophobicContact CG-CG2 4.01Å; P433-F517 HydrophobicContact CB-CE2 3.92Å; P433-F517 HydrophobicContact CB-CZ 4.06Å; P433-F517 HydrophobicContact CG-CE2 4.25Å; P433-F517 HydrophobicContact CG-CZ 4Å; P433-F517 VanDerWaalsContact O-CE2 3.3Å; P433-F517 WeakPolarHBondContact O-CE2 3.36Å
434S89.3Confident92.6Very high136 Ų13639.6 Ų39.695%0.95123%0.23SC*.SBendtrans-69.7-25.5-18052.60000113.1
435D90.3Very high92.6Very high88 Ų8843.8 Ų43.847%0.47125%0.25SC..  trans-130.4137.1179179.676.6000109.6P433 G437P433-D435 PolarHBondContact O-N 2.86Å; D435-G437 WeakPolarHBondContact OD2-CA 3.44Å; D435-G437 PolarHBondContact OD2-N 3.34Å
436P95.1Very high92.6Very high9 Ų939.6 Ų39.66%0.05823%0.234CC..SBendtrans-80.1-13.9-178.432.1-35.6000114.2G438 V439 L440 F517 A521 H524P436-G438 PolarHBondContact O-N 2.69Å; P436-V439 PolarHBondContact O-N 3.2Å; P436-L440 HydrophobicContact CB-CD1 4.22Å; P436-L440 HydrophobicContact CB-CG 4.46Å; P436-L440 WeakPolarHBondContact O-CG 3.23Å; P436-L440 PolarHBondContact O-N 3.35Å; P436-F517 HydrophobicContact CB-CE2 4.11Å; P436-F517 HydrophobicContact CB-CZ 4.11Å; P436-A521 HydrophobicContact CB-CB 3.87Å; P436-H524 HydrophobicContact CG-CB 3.7Å
437G94.6Very high92.7Very high8 Ų837.5 Ų37.58%0.08222%0.22CC..Hα-helixtrans-53.9-49.9-171.500000113.3D435 V439 L440 D441D435-G437 WeakPolarHBondContact OD2-CA 3.44Å; D435-G437 PolarHBondContact OD2-N 3.34Å; G437-V439 VanDerWaalsContact C-N 3.28Å; G437-V439 PolarHBondContact O-N 3.19Å; G437-L440 PolarHBondContact O-N 3.01Å; G437-L440 VanDerWaalsContact O-N 3.1Å; G437-D441 PolarHBondContact O-N 2.58Å
438G94.3Very high92.8Very high17 Ų1741.6 Ų41.618%0.17524%0.239CC..Hα-helixtrans-62.1-31.9178.700000114P436 F442P436-G438 PolarHBondContact O-N 2.69Å; G438-F442 VanDerWaalsContact O-CB 3.25Å; G438-F442 WeakPolarHBondContact O-CB 3.19Å; G438-F442 PolarHBondContact O-N 3.41Å
439V95.5Very high93.1Very high3 Ų341.9 Ų41.92%0.01824%0.236CC..Hα-helixtrans-74.4-39.4174.9175.50000110.9F424 W427 P433 P436 G437 F442 L443 F517F424-V439 HydrophobicContact CE1-CG2 4.26Å; F424-V439 HydrophobicContact CE2-CG2 4.22Å; F424-V439 HydrophobicContact CZ-CG2 3.72Å; W427-V439 HydrophobicContact CZ3-CG2 4.3Å; P433-V439 HydrophobicContact CG-CG2 4.01Å; P436-V439 PolarHBondContact O-N 3.2Å; G437-V439 VanDerWaalsContact C-N 3.28Å; G437-V439 PolarHBondContact O-N 3.19Å; V439-F442 PolarHBondContact O-N 3.4Å; V439-L443 VanDerWaalsContact O-CB 3.27Å; V439-L443 WeakPolarHBondContact O-CB 3.26Å; V439-L443 PolarHBondContact O-N 3.36Å; V439-F517 HydrophobicContact CB-CE1 4.44Å; V439-F517 HydrophobicContact CB-CZ 4.23Å; V439-F517 HydrophobicContact CG1-CE1 4.39Å; V439-F517 HydrophobicContact CG2-CE1 4.21Å; V439-F517 HydrophobicContact CG2-CZ 3.87Å
440L97Very high94.3Very high9 Ų940.2 Ų40.25%0.04723%0.227CC..Hα-helixtrans-66-46.5178.6-68.9173000111.7P436 G437 F442 L443 E444 I476 I480 A521 H524P436-L440 HydrophobicContact CB-CD1 4.22Å; P436-L440 HydrophobicContact CB-CG 4.46Å; P436-L440 WeakPolarHBondContact O-CG 3.23Å; P436-L440 PolarHBondContact O-N 3.35Å; G437-L440 PolarHBondContact O-N 3.01Å; G437-L440 VanDerWaalsContact O-N 3.1Å; L440-F442 VanDerWaalsContact C-N 3.3Å; L440-F442 PolarHBondContact O-N 2.74Å; L440-L443 PolarHBondContact O-N 2.98Å; L440-L443 VanDerWaalsContact O-N 3.12Å; L440-E444 PolarHBondContact O-N 3.21Å; L440-I476 HydrophobicContact CD2-CG2 4.3Å; L440-I480 HydrophobicContact CD2-CD1 3.4Å; L440-I480 VanDerWaalsContact CD2-CD1 3.4Å; L440-A521 WeakPolarHBondContact CD1-O 3.39Å; L440-A521 HydrophobicContact CD2-CB 4.18Å; L440-H524 HydrophobicContact CD1-CB 3.85Å; L440-H524 VanDerWaalsContact CD1-ND1 3.28Å; L440-H524 WeakPolarHBondContact CD1-ND1 3.39Å
441D96.2Very high95Very high111 Ų11142.3 Ų42.359%0.59424%0.236SC*.Hα-helixtrans-60.3-43.2176.7-69.4-13.6000111G437 L443 E444 E445G437-D441 PolarHBondContact O-N 2.58Å; D441-L443 VanDerWaalsContact C-N 3.34Å; D441-L443 PolarHBondContact O-N 2.94Å; D441-E444 PolarHBondContact O-N 3.25Å; D441-E445 WeakPolarHBondContact O-CG 3Å; D441-E445 PolarHBondContact O-N 3.44Å
442F97.4Very high95.4Very high1 Ų145.1 Ų45.10%0.00425%0.252CS..Hα-helixtrans-61-41.1174.6174-107.7000112.9V354 Y396 Y422 F424 G438 V439 L440 E445 V446 F473V354-F442 HydrophobicContact CG1-CE1 3.73Å; V354-F442 HydrophobicContact CG1-CZ 3.93Å; Y396-F442 HydrophobicContact CD1-CB 4.38Å; Y396-F442 AromaticContact CD1-CD2 3.56Å; Y396-F442 HydrophobicContact CD1-CD2 3.56Å; Y396-F442 HydrophobicContact CD1-CE2 4.32Å; Y396-F442 HydrophobicContact CD1-CG 4.43Å; Y396-F442 AromaticContact CD2-CD2 4Å; Y396-F442 HydrophobicContact CD2-CD2 4Å; Y396-F442 HydrophobicContact CD2-CE2 4.03Å; Y396-F442 HydrophobicContact CE1-CD2 4.14Å; Y396-F442 AromaticContact CG-CD2 3.47Å; Y396-F442 HydrophobicContact CG-CD2 3.47Å; Y396-F442 VanDerWaalsContact CG-CD2 3.47Å; Y396-F442 AromaticContact CG-CE2 3.77Å; Y396-F442 HydrophobicContact CG-CE2 3.77Å; Y422-F442 HydrophobicContact CD1-CD2 4.25Å; Y422-F442 AromaticContact CD1-CE2 3.82Å; Y422-F442 HydrophobicContact CD1-CE2 3.82Å; Y422-F442 HydrophobicContact CG-CE2 4.15Å; F424-F442 HydrophobicContact CB-CE1 4.06Å; F424-F442 HydrophobicContact CB-CE2 4.26Å; F424-F442 HydrophobicContact CB-CZ 3.91Å; F424-F442 HydrophobicContact CD2-CB 3.99Å; F424-F442 AromaticContact CD2-CD1 3.74Å; F424-F442 HydrophobicContact CD2-CD1 3.74Å; F424-F442 AromaticContact CD2-CD2 3.96Å; F424-F442 HydrophobicContact CD2-CD2 3.96Å; F424-F442 HydrophobicContact CD2-CE1 4.14Å; F424-F442 HydrophobicContact CD2-CE2 4.29Å; F424-F442 AromaticContact CD2-CG 3.63Å; F424-F442 HydrophobicContact CD2-CG 3.63Å; F424-F442 HydrophobicContact CD2-CZ 4.38Å; F424-F442 HydrophobicContact CE2-CB 4.04Å; F424-F442 HydrophobicContact CE2-CD1 4.42Å; F424-F442 HydrophobicContact CE2-CG 4.2Å; F424-F442 HydrophobicContact CG-CD1 4.47Å; F424-F442 HydrophobicContact CG-CE1 4.48Å; G438-F442 VanDerWaalsContact O-CB 3.25Å; G438-F442 WeakPolarHBondContact O-CB 3.19Å; G438-F442 PolarHBondContact O-N 3.41Å; V439-F442 PolarHBondContact O-N 3.4Å; L440-F442 VanDerWaalsContact C-N 3.3Å; L440-F442 PolarHBondContact O-N 2.74Å; F442-E445 PolarHBondContact O-N 3.45Å; F442-V446 HydrophobicContact CE1-CG2 4.34Å; F442-V446 HydrophobicContact CE2-CG2 4.47Å; F442-V446 HydrophobicContact CZ-CG2 4.26Å; F442-V446 WeakPolarHBondContact O-CG2 3.32Å; F442-V446 PolarHBondContact O-N 3.13Å; F442-V446 VanDerWaalsContact O-N 3.1Å; F442-F473 HydrophobicContact CD1-CD2 4.49Å; F442-F473 AromaticContact CD1-CE2 3.68Å; F442-F473 HydrophobicContact CD1-CE2 3.68Å; F442-F473 HydrophobicContact CD1-CZ 4.44Å; F442-F473 HydrophobicContact CE1-CD2 4.35Å; F442-F473 AromaticContact CE1-CE2 3.63Å; F442-F473 HydrophobicContact CE1-CE2 3.63Å; F442-F473 HydrophobicContact CE1-CZ 4.17Å
443L96.8Very high95.5Very high0 Ų044.8 Ų44.80%025%0.249CC..Hα-helixtrans-69.5-39.7179.7-172.8161.3000111.7V439 L440 D441 E445 V446 H447 F473 I476 D477 I480V439-L443 VanDerWaalsContact O-CB 3.27Å; V439-L443 WeakPolarHBondContact O-CB 3.26Å; V439-L443 PolarHBondContact O-N 3.36Å; L440-L443 PolarHBondContact O-N 2.98Å; L440-L443 VanDerWaalsContact O-N 3.12Å; D441-L443 VanDerWaalsContact C-N 3.34Å; D441-L443 PolarHBondContact O-N 2.94Å; L443-E445 VanDerWaalsContact C-N 3.34Å; L443-E445 PolarHBondContact O-N 2.92Å; L443-V446 PolarHBondContact O-N 3.21Å; L443-H447 WeakPolarHBondContact O-CB 3.22Å; L443-H447 PolarHBondContact O-N 3.09Å; L443-F473 HydrophobicContact CB-CE2 4.14Å; L443-F473 HydrophobicContact CB-CZ 4.39Å; L443-F473 HydrophobicContact CD1-CE2 4.29Å; L443-F473 HydrophobicContact CD1-CZ 4.5Å; L443-F473 HydrophobicContact CG-CE2 4.25Å; L443-F473 HydrophobicContact CG-CZ 4.18Å; L443-I476 HydrophobicContact CD1-CB 4.2Å; L443-I476 HydrophobicContact CD1-CG2 3.65Å; L443-D477 HydrophobicContact CD1-CB 3.82Å; L443-D477 HydrophobicContact CD2-CB 4.36Å; L443-D477 WeakPolarHBondContact CD2-OD1 3.44Å; L443-D477 HydrophobicContact CG-CB 4.16Å; L443-I480 HydrophobicContact CD1-CD1 4.19Å; L443-I480 HydrophobicContact CD2-CD1 4.17Å; L443-I480 HydrophobicContact CD2-CG2 4.31Å
444E95.8Very high95.5Very high22 Ų2251.4 Ų51.410%0.10328%0.28CS..Hα-helixtrans-58.1-45.4172.6-75.7-59.1144.300111.9L440 D441 V446 H447 H448 R484 Y525L440-E444 PolarHBondContact O-N 3.21Å; D441-E444 PolarHBondContact O-N 3.25Å; E444-V446 VanDerWaalsContact C-N 3.35Å; E444-V446 PolarHBondContact O-N 3.04Å; E444-H447 PolarHBondContact O-N 3.28Å; E444-H448 PolarHBondContact O-N 3.34Å; E444-H448 PolarHBondContact O-ND1 3.06Å; E444-H448 IonicContact OE2-CE1 3.85Å; E444-H448 PolarHBondContact OE2-CE1 3.49Å; E444-H448 VanDerWaalsContact OE2-CE1 3.24Å; E444-H448 IonicContact OE2-ND1 2.71Å; E444-H448 IonicContact OE2-NE2 3.95Å; E444-R484 IonicContact OE1-CZ 3.7Å; E444-R484 IonicContact OE1-NH1 3.9Å; E444-R484 IonicContact OE1-NH2 2.79Å; E444-R484 PolarHBondContact OE1-NH2 3Å; E444-R484 IonicContact OE2-CZ 2.95Å; E444-R484 IonicContact OE2-NH1 3Å; E444-R484 PolarHBondContact OE2-NH1 3.38Å; E444-R484 IonicContact OE2-NH2 3.37Å; E444-R484 PolarHBondContact OE2-NH2 2.96Å; E444-Y525 WeakPolarHBondContact OE1-CE2 3.37Å
445E97.7Very high95.6Very high94 Ų9451.1 Ų51.144%0.43927%0.268SS..Hα-helixtrans-63.1-41.2177.4-71.1-62.3137.900112.1Y422 D441 F442 L443 K449Y422-E445 HydrophobicContact CE1-CB 4.02Å; Y422-E445 PolarHBondContact OH-O 3.32Å; D441-E445 WeakPolarHBondContact O-CG 3Å; D441-E445 PolarHBondContact O-N 3.44Å; F442-E445 PolarHBondContact O-N 3.45Å; L443-E445 VanDerWaalsContact C-N 3.34Å; L443-E445 PolarHBondContact O-N 2.92Å; E445-K449 VanDerWaalsContact O-CB 3.31Å; E445-K449 WeakPolarHBondContact O-CB 3.29Å; E445-K449 PolarHBondContact O-N 2.89Å
446V98.1Very high95.9Very high1 Ų148 Ų481%0.00626%0.255CS..Hα-helixtrans-62.6-44.9174.4165.80000111.1V352 V354 Y422 F442 L443 E444 K449 Q450 V459 F473V352-V446 HydrophobicContact CG1-CG1 4.1Å; V354-V446 HydrophobicContact CG2-CG1 3.85Å; V354-V446 HydrophobicContact CG2-CG2 3.94Å; Y422-V446 HydrophobicContact CD1-CG2 3.71Å; Y422-V446 HydrophobicContact CD2-CG2 3.97Å; Y422-V446 HydrophobicContact CE1-CG2 4.15Å; Y422-V446 HydrophobicContact CE2-CG2 4.39Å; Y422-V446 HydrophobicContact CG-CG2 3.6Å; F442-V446 HydrophobicContact CE1-CG2 4.34Å; F442-V446 HydrophobicContact CE2-CG2 4.47Å; F442-V446 HydrophobicContact CZ-CG2 4.26Å; F442-V446 WeakPolarHBondContact O-CG2 3.32Å; F442-V446 PolarHBondContact O-N 3.13Å; F442-V446 VanDerWaalsContact O-N 3.1Å; L443-V446 PolarHBondContact O-N 3.21Å; E444-V446 VanDerWaalsContact C-N 3.35Å; E444-V446 PolarHBondContact O-N 3.04Å; V446-K449 PolarHBondContact O-N 3.1Å; V446-Q450 PolarHBondContact O-N 2.62Å; V446-V459 HydrophobicContact CG1-CG1 4.46Å; V446-F473 HydrophobicContact CG1-CZ 4.34Å
447H95.8Very high96Very high17 Ų1748.3 Ų48.38%0.07926%0.259CS..Hα-helixtrans-61.3-54.7-180176.596.8000111.1K325 L443 E444 K449 Q450 E451 D481 R484K325-H447 PolarHBondContact NZ-ND1 3.28Å; L443-H447 WeakPolarHBondContact O-CB 3.22Å; L443-H447 PolarHBondContact O-N 3.09Å; E444-H447 PolarHBondContact O-N 3.28Å; H447-K449 VanDerWaalsContact C-N 3.27Å; H447-K449 PolarHBondContact O-N 3.13Å; H447-Q450 PolarHBondContact O-N 2.86Å; H447-Q450 VanDerWaalsContact O-N 3.14Å; H447-E451 IonicContact NE2-OE2 2.8Å; H447-E451 PolarHBondContact O-N 3.46Å; H447-D481 IonicContact CE1-OD1 3.95Å; H447-D481 PolarHBondContact CE1-OD1 3.14Å; H447-D481 IonicContact ND1-OD1 3.65Å; H447-D481 PolarHBondContact ND1-OD1 2.9Å; H447-R484 PolarHBondContact CE1-NE 2.82Å; H447-R484 WeakPolarHBondContact NE2-CD 3.41Å; H447-R484 PolarHBondContact NE2-NE 2.99Å
448H96.5Very high96.1Very high90 Ų9048.5 Ų48.542%0.41726%0.259SS..Hα-helixtrans-61.3-37.1179.8-67.1117.4000112E444 E451 S452E444-H448 PolarHBondContact O-N 3.34Å; E444-H448 PolarHBondContact O-ND1 3.06Å; E444-H448 IonicContact OE2-CE1 3.85Å; E444-H448 PolarHBondContact OE2-CE1 3.49Å; E444-H448 VanDerWaalsContact OE2-CE1 3.24Å; E444-H448 IonicContact OE2-ND1 2.71Å; E444-H448 IonicContact OE2-NE2 3.95Å; H448-E451 PolarHBondContact O-N 3.13Å; H448-S452 WeakPolarHBondContact O-CB 3.4Å; H448-S452 PolarHBondContact O-N 2.75Å; H448-S452 PolarHBondContact O-OG 2.8Å
449K98Very high96.3Very high50 Ų5047.7 Ų47.722%0.21725%0.251CS..Hα-helixtrans-62.4-47.2175.1-176.856.558.71760111.6V352 W420 Y422 E445 V446 H447 S452 I453V352-K449 HydrophobicContact CG2-CG 4Å; W420-K449 HydrophobicContact CB-CG 4.13Å; W420-K449 HydrophobicContact CD2-CD 3.91Å; W420-K449 HydrophobicContact CD2-CG 4.41Å; W420-K449 HydrophobicContact CG-CD 3.82Å; W420-K449 HydrophobicContact CG-CG 3.88Å; Y422-K449 HydrophobicContact CE2-CB 4.17Å; Y422-K449 HydrophobicContact CE2-CG 4.06Å; Y422-K449 WeakPolarHBondContact OH-CB 3.28Å; E445-K449 VanDerWaalsContact O-CB 3.31Å; E445-K449 WeakPolarHBondContact O-CB 3.29Å; E445-K449 PolarHBondContact O-N 2.89Å; V446-K449 PolarHBondContact O-N 3.1Å; H447-K449 VanDerWaalsContact C-N 3.27Å; H447-K449 PolarHBondContact O-N 3.13Å; K449-S452 PolarHBondContact O-N 3.42Å; K449-S452 PolarHBondContact O-OG 3.15Å; K449-I453 HydrophobicContact CD-CD1 4.07Å; K449-I453 HydrophobicContact CG-CD1 4.27Å; K449-I453 WeakPolarHBondContact O-CD1 3.4Å; K449-I453 WeakPolarHBondContact O-CG1 3.38Å
450Q96.9Very high96.5Very high19 Ų1947.6 Ų47.69%0.08925%0.25CS..Hα-helixtrans-61.6-45.7178.6178.167.611.900111.3K325 V352 V446 H447 S452 I453 A456 G457 V459K325-Q450 HydrophobicContact CD-CG 4.01Å; K325-Q450 HydrophobicContact CG-CG 4.22Å; V352-Q450 HydrophobicContact CG2-CB 4.28Å; V446-Q450 PolarHBondContact O-N 2.62Å; H447-Q450 PolarHBondContact O-N 2.86Å; H447-Q450 VanDerWaalsContact O-N 3.14Å; Q450-S452 VanDerWaalsContact C-N 3.32Å; Q450-S452 PolarHBondContact O-N 3.22Å; Q450-I453 PolarHBondContact O-N 3.44Å; Q450-A456 VanDerWaalsContact NE2-CB 3.33Å; Q450-G457 PolarHBondContact NE2-O 2.9Å; Q450-V459 HydrophobicContact CB-CG2 4.29Å; Q450-V459 HydrophobicContact CG-CG2 3.88Å
451E94.3Very high96.6Very high134 Ų13447.1 Ų47.163%0.62625%0.248SC*.Hα-helixtrans-65.4-34.3-179.4-168.2-178.8-157.500112.6H447 H448 I453H447-E451 IonicContact NE2-OE2 2.8Å; H447-E451 PolarHBondContact O-N 3.46Å; H448-E451 PolarHBondContact O-N 3.13Å; E451-I453 PolarHBondContact O-N 2.97Å
452S96.6Very high96.7Very high83 Ų8341.9 Ų41.958%0.5822%0.22SC*.THydrogen-bonded Turntrans-67.4-14.5178.772.90000114.4H448 K449 Q450H448-S452 WeakPolarHBondContact O-CB 3.4Å; H448-S452 PolarHBondContact O-N 2.75Å; H448-S452 PolarHBondContact O-OG 2.8Å; K449-S452 PolarHBondContact O-N 3.42Å; K449-S452 PolarHBondContact O-OG 3.15Å; Q450-S452 VanDerWaalsContact C-N 3.32Å; Q450-S452 PolarHBondContact O-N 3.22Å
453I95.8Very high96.7Very high31 Ų3141.9 Ų41.916%0.15922%0.22CC..SBendtrans-104.9111.4-174.9-56.6165.4000109.6R351 K449 Q450 E451 D455 A456R351-I453 HydrophobicContact CB-CD1 3.84Å; R351-I453 HydrophobicContact CB-CG2 4.32Å; R351-I453 HydrophobicContact CG-CG2 3.94Å; K449-I453 HydrophobicContact CD-CD1 4.07Å; K449-I453 HydrophobicContact CG-CD1 4.27Å; K449-I453 WeakPolarHBondContact O-CD1 3.4Å; K449-I453 WeakPolarHBondContact O-CG1 3.38Å; Q450-I453 PolarHBondContact O-N 3.44Å; E451-I453 PolarHBondContact O-N 2.97Å; I453-D455 PolarHBondContact O-N 2.82Å; I453-A456 HydrophobicContact CB-CB 4Å; I453-A456 HydrophobicContact CG2-CB 3.96Å; I453-A456 WeakPolarHBondContact O-CB 3.31Å; I453-A456 PolarHBondContact O-N 2.95Å
454M93Very high96.7Very high156 Ų15641.9 Ų41.977%0.76822%0.22SC*.THydrogen-bonded Turntrans-58.2134.3176.4-17017467.800111.5A456M454-A456 PolarHBondContact O-N 2.77Å; M454-A456 VanDerWaalsContact O-N 3.11Å
455D91.9Very high96.7Very high130 Ų13040.9 Ų40.970%0.69522%0.215SC*.THydrogen-bonded Turntrans52.330.2178.9-53-43.8000114.1N349 I453 G457N349-D455 PolarHBondContact ND2-O 2.8Å; I453-D455 PolarHBondContact O-N 2.82Å; D455-G457 PolarHBondContact O-N 3.43Å
456A96Very high96.8Very high24 Ų2436.4 Ų36.420%0.19819%0.194CC..  trans-62132.1174.700000111R351 Q450 I453 M454R351-A456 HydrophobicContact CB-CB 4.04Å; R351-A456 HydrophobicContact CG-CB 3.63Å; Q450-A456 VanDerWaalsContact NE2-CB 3.33Å; I453-A456 HydrophobicContact CB-CB 4Å; I453-A456 HydrophobicContact CG2-CB 3.96Å; I453-A456 WeakPolarHBondContact O-CB 3.31Å; I453-A456 PolarHBondContact O-N 2.95Å; M454-A456 PolarHBondContact O-N 2.77Å; M454-A456 VanDerWaalsContact O-N 3.11Å
457G97Very high96.7Very high14 Ų1436.4 Ų36.414%0.14419%0.194CC..  trans-68.3-175.8172.100000113.1E348 N349 Q450 D455E348-G457 WeakPolarHBondContact O-CA 3.36Å; N349-G457 PolarHBondContact O-N 2.98Å; Q450-G457 PolarHBondContact NE2-O 2.9Å; D455-G457 PolarHBondContact O-N 3.43Å
458P98.3Very high96.8Very high13 Ų1335.6 Ų35.68%0.08419%0.19CC..PPolyproline II helixtrans-59.2146.8-177.225.3-36000112.7S326 I328 E348 S350 V460S326-P458 CarbonylContact O-C 3.55Å; S326-P458 VanDerWaalsContact O-CA 3.23Å; S326-P458 WeakPolarHBondContact O-CA 3.47Å; S326-P458 WeakPolarHBondContact O-CB 3.46Å; S326-P458 WeakPolarHBondContact OG-CB 3.49Å; I328-P458 HydrophobicContact CD1-CB 4.44Å; I328-P458 HydrophobicContact CD1-CG 3.67Å; I328-P458 HydrophobicContact CG1-CB 3.88Å; I328-P458 HydrophobicContact CG1-CG 3.63Å; E348-P458 HydrophobicContact CB-CG 4.2Å; E348-P458 WeakPolarHBondContact O-CD 3.4Å; S350-P458 VanDerWaalsContact CB-O 3.26Å; S350-P458 WeakPolarHBondContact CB-O 3.49Å; S350-P458 PolarHBondContact OG-O 2.74Å; P458-V460 PolarHBondContact O-N 2.94Å
459V98.8Very high96.9Very high0 Ų031.5 Ų31.50%017%0.171CC..EExtended strand (participates in β ladder)trans-72.8122.8174.1-178.70000109K325 S326 Y327 I328 V352 V354 V446 Q450 V461K325-V459 HydrophobicContact CD-CG2 4.18Å; K325-V459 HydrophobicContact CG-CG2 4.21Å; S326-V459 PolarHBondContact O-N 2.82Å; Y327-V459 CarbonylContact C-O 3.51Å; Y327-V459 VanDerWaalsContact CA-O 3.26Å; Y327-V459 WeakPolarHBondContact CA-O 3.26Å; Y327-V459 HydrophobicContact CD1-CB 4.16Å; I328-V459 PolarHBondContact N-O 2.87Å; V352-V459 HydrophobicContact CB-CG1 4.21Å; V352-V459 HydrophobicContact CB-CG2 4.39Å; V352-V459 HydrophobicContact CG1-CG1 4.1Å; V354-V459 HydrophobicContact CG2-CG1 3.86Å; V446-V459 HydrophobicContact CG1-CG1 4.46Å; Q450-V459 HydrophobicContact CB-CG2 4.29Å; Q450-V459 HydrophobicContact CG-CG2 3.88Å; V459-V461 HydrophobicContact CG1-CG2 4.08Å
460V98.9Very high96.9Very high0 Ų029.1 Ų29.10%016%0.161CC..EExtended strand (participates in β ladder)trans-83.1120.8177.6179.50000108.9I328 T330 F341 M344 V345 S350 V352 I353 V354 P458I328-V460 HydrophobicContact CB-CG2 4.18Å; I328-V460 HydrophobicContact CD1-CG2 4.23Å; I328-V460 HydrophobicContact CG1-CG2 4.48Å; T330-V460 HydrophobicContact CG2-CG1 3.87Å; F341-V460 HydrophobicContact CE2-CG1 3.89Å; F341-V460 HydrophobicContact CZ-CG1 4.15Å; M344-V460 HydrophobicContact CE-CG1 3.83Å; M344-V460 HydrophobicContact CE-CG2 4.14Å; V345-V460 HydrophobicContact CG2-CG2 4.32Å; S350-V460 WeakPolarHBondContact OG-CG2 3.39Å; V352-V460 PolarHBondContact O-N 3.49Å; I353-V460 CarbonylContact C-O 3.54Å; I353-V460 WeakPolarHBondContact CA-O 3.44Å; I353-V460 HydrophobicContact CG1-CB 4.22Å; I353-V460 HydrophobicContact CG2-CB 4.46Å; I353-V460 HydrophobicContact CG2-CG1 4.47Å; V354-V460 PolarHBondContact N-O 3.43Å; P458-V460 PolarHBondContact O-N 2.94Å
461V98.9Very high97Very high0 Ų028.2 Ų28.20%016%0.157CC..EExtended strand (participates in β ladder)trans-120.9125.9179.8-169.60000109.5Y327 I328 T330 V354 V459 T470 F473 I474Y327-V461 HydrophobicContact CD1-CG2 4.29Å; I328-V461 PolarHBondContact O-N 2.97Å; T330-V461 PolarHBondContact N-O 3.34Å; T330-V461 VanDerWaalsContact N-O 3.09Å; V354-V461 HydrophobicContact CB-CB 4.42Å; V354-V461 HydrophobicContact CB-CG1 4.14Å; V354-V461 HydrophobicContact CB-CG2 4.17Å; V354-V461 HydrophobicContact CG1-CG1 4.11Å; V354-V461 WeakPolarHBondContact O-CA 3.34Å; V459-V461 HydrophobicContact CG1-CG2 4.08Å; V461-T470 HydrophobicContact CB-CG2 4.04Å; V461-T470 HydrophobicContact CG1-CG2 3.88Å; V461-T470 WeakPolarHBondContact O-CG2 3.4Å; V461-F473 HydrophobicContact CG1-CB 4.42Å; V461-F473 HydrophobicContact CG1-CD1 3.84Å; V461-F473 HydrophobicContact CG1-CG 4.37Å; V461-F473 HydrophobicContact CG2-CD1 4.17Å; V461-F473 HydrophobicContact CG2-CE1 4.35Å; V461-I474 HydrophobicContact CB-CD1 4.08Å; V461-I474 HydrophobicContact CB-CG1 4.16Å; V461-I474 HydrophobicContact CG1-CG1 4.33Å; V461-I474 HydrophobicContact CG2-CD1 4.2Å; V461-I474 HydrophobicContact CG2-CG1 3.93Å
462H98.9Very high97.2Very high0 Ų021.8 Ų21.80%013%0.127CC..EExtended strand (participates in β ladder)trans-142.7157.6179.777.887.7000113.5T330 V354 M355 T356 Y370 T470T330-H462 HydrophobicContact CG2-CB 3.57Å; T330-H462 WeakPolarHBondContact O-CA 3.33Å; T330-H462 WeakPolarHBondContact O-CB 3.07Å; V354-H462 PolarHBondContact O-N 2.95Å; M355-H462 WeakPolarHBondContact CG-CE1 3.46Å; T356-H462 PolarHBondContact N-O 3.42Å; T356-H462 PolarHBondContact OG1-O 3.5Å; Y370-H462 AromaticContact CE1-CE1 3.7Å; Y370-H462 AromaticContact CE1-NE2 3.5Å; Y370-H462 WeakPolarHBondContact CE1-NE2 3.5Å; Y370-H462 AromaticContact CZ-NE2 3.54Å; Y370-H462 PolarHBondContact OH-NE2 3.49Å; H462-T470 WeakPolarHBondContact CA-OG1 3.39Å
463C97.1Very high97.3Very high1 Ų118 Ų181%0.00710%0.1CC..  trans-137.8-122.3173.558.90000109.3G332 T356 G466 R469 T470G332-C463 WeakPolarHBondContact CA-O 3.36Å; G332-C463 PolarHBondContact N-O 2.76Å; G332-C463 VanDerWaalsContact N-O 3.1Å; T356-C463 WeakPolarHBondContact OG1-CB 3.46Å; C463-G466 PolarHBondContact SG-N 2.94Å; C463-R469 HydrophobicContact CB-CB 4.08Å; C463-T470 PolarHBondContact N-OG1 3.44Å; C463-T470 PolarHBondContact SG-OG1 2.83Å
464S96.4Very high97.4Very high0 Ų016.5 Ų16.50%09%0.092CC..SBendtrans-90.7-69.8170.2-167.70000112R278 Y279 Q331 G332R278-S464 WeakPolarHBondContact CD-O 3.29Å; Y279-S464 PolarHBondContact OH-OG 3.06Å; Q331-S464 WeakPolarHBondContact CB-O 3.49Å; G332-S464 PolarHBondContact N-O 2.82Å
465A96.9Very high97.7Very high1 Ų19 Ų91%0.0086%0.056CC..SBendtrans-85.3-15.2178.200000113.2Y62 Y279 I282 I467 R505Y62-A465 HydrophobicContact CD1-CB 4.36Å; Y279-A465 HydrophobicContact CD2-CB 3.72Å; Y279-A465 HydrophobicContact CE2-CB 3.66Å; I282-A465 HydrophobicContact CD1-CB 3.88Å; I282-A465 HydrophobicContact CG2-CB 4.38Å; A465-I467 HydrophobicContact CB-CD1 4.32Å; A465-I467 HydrophobicContact CB-CG1 3.99Å; A465-R505 PolarHBondContact O-NH2 3.12Å
466G97.8Very high98Very high0 Ų02.9 Ų2.90%02%0.022CC..SBendtrans75.328.9-178.300000114.2T330 C463 R505T330-G466 WeakPolarHBondContact O-CA 3.47Å; C463-G466 PolarHBondContact SG-N 2.94Å; G466-R505 PolarHBondContact O-NE 2.88Å
467I97.9Very high98.1Very high1 Ų11.7 Ų1.71%0.0051%0.013CC..SBendtrans-132.1-43.3-176.164.5177.4000113.5D61 A72 I282 A465 G471 R505 S506 M508 V509 Q510D61-I467 WeakPolarHBondContact O-CD1 3.39Å; D61-I467 VanDerWaalsContact O-CG1 3.31Å; D61-I467 WeakPolarHBondContact O-CG1 3.29Å; A72-I467 HydrophobicContact CB-CD1 3.73Å; I282-I467 HydrophobicContact CD1-CD1 4.23Å; I282-I467 HydrophobicContact CG2-CD1 4.13Å; I282-I467 HydrophobicContact CG2-CG2 4.2Å; A465-I467 HydrophobicContact CB-CD1 4.32Å; A465-I467 HydrophobicContact CB-CG1 3.99Å; I467-G471 WeakPolarHBondContact O-CA 3.47Å; I467-G471 PolarHBondContact O-N 2.96Å; I467-R505 HydrophobicContact CG2-CG 4.33Å; I467-S506 WeakPolarHBondContact CG2-O 3.32Å; I467-M508 HydrophobicContact CB-SD 4.48Å; I467-M508 WeakPolarHBondContact O-CA 3.38Å; I467-V509 PolarHBondContact O-N 3.42Å; I467-Q510 HydrophobicContact CD1-CG 4.18Å; I467-Q510 HydrophobicContact CG1-CG 3.98Å
468G96.6Very high98.1Very high0 Ų01.3 Ų1.30%01%0.007CC..Hα-helixtrans-73.3-90.4-179.400000113.5G60 T470 G471 T472G60-G468 VanDerWaalsContact O-CA 3.26Å; G60-G468 WeakPolarHBondContact O-CA 3.49Å; G468-T470 PolarHBondContact O-N 3.32Å; G468-G471 PolarHBondContact O-N 2.78Å; G468-T472 PolarHBondContact O-N 3.32Å; G468-T472 PolarHBondContact O-OG1 2.94Å; G468-T472 VanDerWaalsContact O-OG1 3.13Å
469R98.1Very high98Very high4 Ų40.7 Ų0.72%0.0150%0.003CC..Hα-helixtrans-55.1-39.6178.7-54.6-177.5-172165.85112.5T356 E361 W427 P428 D429 C463 T472 F473T356-R469 WeakPolarHBondContact O-CD 3.43Å; T356-R469 PolarHBondContact O-NH1 3.39Å; T356-R469 VanDerWaalsContact O-NH1 3.07Å; E361-R469 IonicContact OE1-CZ 3.98Å; E361-R469 IonicContact OE1-NH1 3.5Å; E361-R469 PolarHBondContact OE1-NH1 3.03Å; E361-R469 IonicContact OE1-NH2 3.39Å; E361-R469 IonicContact OE2-CZ 2.96Å; E361-R469 IonicContact OE2-NH1 3.67Å; E361-R469 PolarHBondContact OE2-NH1 3.18Å; E361-R469 IonicContact OE2-NH2 3.47Å; E361-R469 PolarHBondContact OE2-NH2 2.78Å; W427-R469 VanDerWaalsContact CD1-CD 3.47Å; W427-R469 HydrophobicContact CD2-CG 4.13Å; W427-R469 HydrophobicContact CG-CG 4.42Å; W427-R469 HydrophobicContact CH2-CB 4.48Å; W427-R469 HydrophobicContact CZ2-CB 4.24Å; W427-R469 HydrophobicContact CZ2-CG 3.96Å; P428-R469 PolarHBondContact O-NH2 2.7Å; D429-R469 PolarHBondContact O-NH2 3.24Å; C463-R469 HydrophobicContact CB-CB 4.08Å; R469-T472 PolarHBondContact O-N 3.23Å; R469-F473 WeakPolarHBondContact O-CB 3.3Å; R469-F473 PolarHBondContact O-N 3.13Å
470T98.7Very high97.8Very high0 Ų00.7 Ų0.70%00%0.003CC..Hα-helixtrans-58.4-48.4173.7-63.90000111.9A329 V461 H462 C463 G468 F473 I474 M508A329-T470 HydrophobicContact CB-CG2 3.77Å; V461-T470 HydrophobicContact CB-CG2 4.04Å; V461-T470 HydrophobicContact CG1-CG2 3.88Å; V461-T470 WeakPolarHBondContact O-CG2 3.4Å; H462-T470 WeakPolarHBondContact CA-OG1 3.39Å; C463-T470 PolarHBondContact N-OG1 3.44Å; C463-T470 PolarHBondContact SG-OG1 2.83Å; G468-T470 PolarHBondContact O-N 3.32Å; T470-F473 PolarHBondContact O-N 3.24Å; T470-I474 HydrophobicContact CG2-CD1 3.89Å; T470-I474 WeakPolarHBondContact O-CB 3.28Å; T470-I474 WeakPolarHBondContact O-CG1 3.4Å; T470-I474 PolarHBondContact O-N 3.01Å; T470-M508 HydrophobicContact CG2-CE 4.43Å
471G98.4Very high97.6Very high0 Ų02.2 Ų2.20%01%0.011CC..Hα-helixtrans-66.9-39.4178.200000112.6I467 G468 I474 V475 M508I467-G471 WeakPolarHBondContact O-CA 3.47Å; I467-G471 PolarHBondContact O-N 2.96Å; G468-G471 PolarHBondContact O-N 2.78Å; G471-I474 PolarHBondContact O-N 3.34Å; G471-V475 WeakPolarHBondContact O-CB 3.44Å; G471-V475 WeakPolarHBondContact O-CG2 3.18Å; G471-V475 PolarHBondContact O-N 2.81Å; G471-M508 VanDerWaalsContact CA-CE 3.44Å
472T98.7Very high97.2Very high0 Ų03.5 Ų3.50%02%0.018CC..Hα-helixtrans-59.7-49.7174.8-55.80000111.5W427 G468 R469 V475 I476 Q514 F517 I518W427-T472 HydrophobicContact CH2-CG2 3.87Å; G468-T472 PolarHBondContact O-N 3.32Å; G468-T472 PolarHBondContact O-OG1 2.94Å; G468-T472 VanDerWaalsContact O-OG1 3.13Å; R469-T472 PolarHBondContact O-N 3.23Å; T472-V475 PolarHBondContact O-N 3.46Å; T472-I476 HydrophobicContact CG2-CD1 3.95Å; T472-I476 VanDerWaalsContact O-CG1 3.27Å; T472-I476 WeakPolarHBondContact O-CG1 3.43Å; T472-I476 PolarHBondContact O-N 3.17Å; T472-I476 VanDerWaalsContact O-N 3.09Å; T472-Q514 WeakPolarHBondContact OG1-CB 3.27Å; T472-F517 HydrophobicContact CG2-CD1 3.99Å; T472-I518 HydrophobicContact CG2-CD1 4.45Å; T472-I518 HydrophobicContact CG2-CG1 3.92Å
473F98.7Very high96.8Very high2 Ų23.6 Ų3.61%0.0092%0.019CC..Hα-helixtrans-59.2-51.3178-177.9-89.2000111.8V354 F442 L443 V446 V461 R469 T470 V475 I476 D477V354-F473 HydrophobicContact CB-CE1 4.39Å; V354-F473 HydrophobicContact CG1-CD1 4.21Å; V354-F473 HydrophobicContact CG1-CD2 4.42Å; V354-F473 HydrophobicContact CG1-CE1 3.96Å; V354-F473 HydrophobicContact CG1-CE2 4.19Å; V354-F473 HydrophobicContact CG1-CG 4.44Å; V354-F473 HydrophobicContact CG1-CZ 3.94Å; V354-F473 HydrophobicContact CG2-CE1 4.08Å; V354-F473 HydrophobicContact CG2-CZ 4.16Å; F442-F473 HydrophobicContact CD1-CD2 4.49Å; F442-F473 AromaticContact CD1-CE2 3.68Å; F442-F473 HydrophobicContact CD1-CE2 3.68Å; F442-F473 HydrophobicContact CD1-CZ 4.44Å; F442-F473 HydrophobicContact CE1-CD2 4.35Å; F442-F473 AromaticContact CE1-CE2 3.63Å; F442-F473 HydrophobicContact CE1-CE2 3.63Å; F442-F473 HydrophobicContact CE1-CZ 4.17Å; L443-F473 HydrophobicContact CB-CE2 4.14Å; L443-F473 HydrophobicContact CB-CZ 4.39Å; L443-F473 HydrophobicContact CD1-CE2 4.29Å; L443-F473 HydrophobicContact CD1-CZ 4.5Å; L443-F473 HydrophobicContact CG-CE2 4.25Å; L443-F473 HydrophobicContact CG-CZ 4.18Å; V446-F473 HydrophobicContact CG1-CZ 4.34Å; V461-F473 HydrophobicContact CG1-CB 4.42Å; V461-F473 HydrophobicContact CG1-CD1 3.84Å; V461-F473 HydrophobicContact CG1-CG 4.37Å; V461-F473 HydrophobicContact CG2-CD1 4.17Å; V461-F473 HydrophobicContact CG2-CE1 4.35Å; R469-F473 WeakPolarHBondContact O-CB 3.3Å; R469-F473 PolarHBondContact O-N 3.13Å; T470-F473 PolarHBondContact O-N 3.24Å; F473-V475 VanDerWaalsContact C-N 3.34Å; F473-V475 PolarHBondContact O-N 3.19Å; F473-I476 PolarHBondContact O-N 3.37Å; F473-D477 WeakPolarHBondContact O-CB 3.38Å; F473-D477 PolarHBondContact O-N 2.89Å
474I98.7Very high96.5Very high0 Ų07.2 Ų7.20%03%0.032CC..Hα-helixtrans-60.1-43.5-179-71.3171.1000111.2I310 Y327 A329 V461 T470 G471 D477 I478 M508I310-I474 HydrophobicContact CG1-CD1 4.42Å; I310-I474 HydrophobicContact CG2-CG2 4.21Å; Y327-I474 HydrophobicContact CD1-CG1 4.08Å; Y327-I474 HydrophobicContact CD2-CG2 3.9Å; Y327-I474 HydrophobicContact CE2-CG2 4.14Å; Y327-I474 HydrophobicContact CG-CD1 4.33Å; Y327-I474 HydrophobicContact CG-CG1 4.14Å; Y327-I474 HydrophobicContact CG-CG2 4.11Å; A329-I474 HydrophobicContact CB-CD1 4Å; V461-I474 HydrophobicContact CB-CD1 4.08Å; V461-I474 HydrophobicContact CB-CG1 4.16Å; V461-I474 HydrophobicContact CG1-CG1 4.33Å; V461-I474 HydrophobicContact CG2-CD1 4.2Å; V461-I474 HydrophobicContact CG2-CG1 3.93Å; T470-I474 HydrophobicContact CG2-CD1 3.89Å; T470-I474 WeakPolarHBondContact O-CB 3.28Å; T470-I474 WeakPolarHBondContact O-CG1 3.4Å; T470-I474 PolarHBondContact O-N 3.01Å; G471-I474 PolarHBondContact O-N 3.34Å; I474-D477 PolarHBondContact O-N 3.41Å; I474-I478 HydrophobicContact CG2-CD1 3.65Å; I474-I478 HydrophobicContact CG2-CG1 4.27Å; I474-I478 WeakPolarHBondContact O-CG1 2.95Å; I474-I478 PolarHBondContact O-N 2.99Å; I474-M508 HydrophobicContact CD1-CE 3.96Å
475V98.6Very high96.1Very high0 Ų013 Ų130%06%0.059CC..Hα-helixtrans-67.1-40.7-178.4170.60000111.7G471 T472 F473 D477 I478 L479 T497 I498 V501 V509 I518G471-V475 WeakPolarHBondContact O-CB 3.44Å; G471-V475 WeakPolarHBondContact O-CG2 3.18Å; G471-V475 PolarHBondContact O-N 2.81Å; T472-V475 PolarHBondContact O-N 3.46Å; F473-V475 VanDerWaalsContact C-N 3.34Å; F473-V475 PolarHBondContact O-N 3.19Å; V475-D477 VanDerWaalsContact C-N 3.32Å; V475-I478 PolarHBondContact O-N 2.88Å; V475-L479 HydrophobicContact CG1-CD1 3.87Å; V475-L479 HydrophobicContact CG1-CG 4.46Å; V475-L479 VanDerWaalsContact O-CG 3.29Å; V475-L479 WeakPolarHBondContact O-CG 3.37Å; V475-L479 PolarHBondContact O-N 3.35Å; V475-T497 HydrophobicContact CG1-CG2 4.17Å; V475-I498 HydrophobicContact CB-CG1 4.42Å; V475-I498 HydrophobicContact CG1-CG1 3.76Å; V475-I498 HydrophobicContact CG2-CG1 3.94Å; V475-V501 HydrophobicContact CG2-CB 4.38Å; V475-V501 HydrophobicContact CG2-CG2 4.07Å; V475-V509 HydrophobicContact CG2-CG2 4.2Å; V475-I518 HydrophobicContact CB-CD1 4.22Å; V475-I518 HydrophobicContact CG1-CD1 3.96Å; V475-I518 HydrophobicContact CG1-CG2 3.95Å
476I98.5Very high95.5Very high0 Ų018.6 Ų18.60%08%0.083CC..Hα-helixtrans-59.8-47.4174.6-66.3167000109.5L440 L443 T472 F473 I478 L479 I480 F517 I518 A521L440-I476 HydrophobicContact CD2-CG2 4.3Å; L443-I476 HydrophobicContact CD1-CB 4.2Å; L443-I476 HydrophobicContact CD1-CG2 3.65Å; T472-I476 HydrophobicContact CG2-CD1 3.95Å; T472-I476 VanDerWaalsContact O-CG1 3.27Å; T472-I476 WeakPolarHBondContact O-CG1 3.43Å; T472-I476 PolarHBondContact O-N 3.17Å; T472-I476 VanDerWaalsContact O-N 3.09Å; F473-I476 PolarHBondContact O-N 3.37Å; I476-I478 PolarHBondContact O-N 3.33Å; I476-L479 PolarHBondContact O-N 3.09Å; I476-I480 HydrophobicContact CG2-CD1 3.59Å; I476-I480 HydrophobicContact CG2-CG1 4.26Å; I476-I480 WeakPolarHBondContact O-CB 3.4Å; I476-I480 WeakPolarHBondContact O-CG1 3.49Å; I476-I480 PolarHBondContact O-N 2.81Å; I476-F517 HydrophobicContact CD1-CD1 3.99Å; I476-F517 HydrophobicContact CD1-CE1 3.95Å; I476-I518 HydrophobicContact CD1-CG1 4.34Å; I476-I518 HydrophobicContact CG1-CB 4.22Å; I476-I518 HydrophobicContact CG1-CG1 3.93Å; I476-I518 HydrophobicContact CG1-CG2 4.13Å; I476-A521 HydrophobicContact CD1-CB 3.83Å; I476-A521 HydrophobicContact CG1-CB 4.18Å; I476-A521 HydrophobicContact CG2-CB 4.1Å
477D98.1Very high94.9Very high0 Ų020 Ų200%010%0.098CC..Hα-helixtrans-62.5-41.5-178.6-164.626000112.3K325 Y327 L443 F473 I474 V475 L479 I480 D481K325-D477 WeakPolarHBondContact CE-OD2 3.31Å; K325-D477 IonicContact NZ-OD1 3.78Å; K325-D477 PolarHBondContact NZ-OD1 2.79Å; K325-D477 IonicContact NZ-OD2 2.84Å; K325-D477 PolarHBondContact NZ-OD2 3.42Å; Y327-D477 HydrophobicContact CE1-CB 4.46Å; Y327-D477 WeakPolarHBondContact CE1-OD2 3.29Å; Y327-D477 PolarHBondContact OH-OD2 3.18Å; Y327-D477 VanDerWaalsContact OH-OD2 3.09Å; L443-D477 HydrophobicContact CD1-CB 3.82Å; L443-D477 HydrophobicContact CD2-CB 4.36Å; L443-D477 WeakPolarHBondContact CD2-OD1 3.44Å; L443-D477 HydrophobicContact CG-CB 4.16Å; F473-D477 WeakPolarHBondContact O-CB 3.38Å; F473-D477 PolarHBondContact O-N 2.89Å; I474-D477 PolarHBondContact O-N 3.41Å; V475-D477 VanDerWaalsContact C-N 3.32Å; D477-L479 PolarHBondContact O-N 2.94Å; D477-I480 PolarHBondContact O-N 2.83Å; D477-D481 WeakPolarHBondContact O-CB 3.34Å; D477-D481 PolarHBondContact O-N 3.3Å
478I97.1Very high94.1Very high5 Ų521.2 Ų21.23%0.02611%0.105CC..Hα-helixtrans-60.9-46.1174-68.4170.8000111.5P312 Y327 I474 V475 I476 D481 I482 T497 M500 V501P312-I478 HydrophobicContact CB-CD1 4.17Å; P312-I478 HydrophobicContact CB-CG1 4.06Å; P312-I478 HydrophobicContact CB-CG2 4.05Å; Y327-I478 HydrophobicContact CE2-CD1 4.02Å; Y327-I478 HydrophobicContact CE2-CG1 3.67Å; I474-I478 HydrophobicContact CG2-CD1 3.65Å; I474-I478 HydrophobicContact CG2-CG1 4.27Å; I474-I478 WeakPolarHBondContact O-CG1 2.95Å; I474-I478 PolarHBondContact O-N 2.99Å; V475-I478 PolarHBondContact O-N 2.88Å; I476-I478 PolarHBondContact O-N 3.33Å; I478-D481 PolarHBondContact O-N 3.11Å; I478-I482 HydrophobicContact CG2-CD1 4.22Å; I478-I482 VanDerWaalsContact O-CG1 3.31Å; I478-I482 WeakPolarHBondContact O-CG1 3.37Å; I478-I482 PolarHBondContact O-N 3.41Å; I478-I482 VanDerWaalsContact O-N 3.13Å; I478-T497 HydrophobicContact CB-CG2 4.35Å; I478-T497 HydrophobicContact CG2-CG2 3.8Å; I478-M500 HydrophobicContact CD1-CE 4.21Å; I478-V501 HydrophobicContact CD1-CG2 3.82Å
479L96.1Very high93.3Very high0 Ų027.3 Ų27.30%014%0.138CC..Hα-helixtrans-67.7-40.7-178.5-69.1168000111.6V475 I476 D477 I482 I483 I492 V494 T497 I518 V522V475-L479 HydrophobicContact CG1-CD1 3.87Å; V475-L479 HydrophobicContact CG1-CG 4.46Å; V475-L479 VanDerWaalsContact O-CG 3.29Å; V475-L479 WeakPolarHBondContact O-CG 3.37Å; V475-L479 PolarHBondContact O-N 3.35Å; I476-L479 PolarHBondContact O-N 3.09Å; D477-L479 PolarHBondContact O-N 2.94Å; L479-I482 PolarHBondContact O-N 3.16Å; L479-I483 WeakPolarHBondContact O-CD1 3.42Å; L479-I483 WeakPolarHBondContact O-CG1 3.28Å; L479-I483 PolarHBondContact O-N 3.34Å; L479-I483 VanDerWaalsContact O-N 3.16Å; L479-I492 HydrophobicContact CD2-CB 4.32Å; L479-I492 HydrophobicContact CD2-CG2 4.43Å; L479-V494 HydrophobicContact CD1-CG1 4.45Å; L479-V494 HydrophobicContact CD1-CG2 3.94Å; L479-T497 HydrophobicContact CD2-CG2 4.31Å; L479-T497 HydrophobicContact CG-CG2 4.38Å; L479-I518 HydrophobicContact CD1-CG2 3.7Å; L479-V522 HydrophobicContact CB-CG2 3.95Å; L479-V522 HydrophobicContact CD1-CG2 3.91Å
480I95.7Very high92.5Very high0 Ų027.6 Ų27.60%014%0.14CC..Hα-helixtrans-64.8-42.2175.7-73.2177.4000111.1L440 L443 I476 D477 I482 I483 R484 Y525L440-I480 HydrophobicContact CD2-CD1 3.4Å; L440-I480 VanDerWaalsContact CD2-CD1 3.4Å; L443-I480 HydrophobicContact CD1-CD1 4.19Å; L443-I480 HydrophobicContact CD2-CD1 4.17Å; L443-I480 HydrophobicContact CD2-CG2 4.31Å; I476-I480 HydrophobicContact CG2-CD1 3.59Å; I476-I480 HydrophobicContact CG2-CG1 4.26Å; I476-I480 WeakPolarHBondContact O-CB 3.4Å; I476-I480 WeakPolarHBondContact O-CG1 3.49Å; I476-I480 PolarHBondContact O-N 2.81Å; D477-I480 PolarHBondContact O-N 2.83Å; I480-I482 VanDerWaalsContact C-N 3.31Å; I480-I482 PolarHBondContact O-N 2.94Å; I480-I483 CarbonylContact O-C 3.49Å; I480-I483 PolarHBondContact O-N 3.01Å; I480-I483 VanDerWaalsContact O-N 3.14Å; I480-R484 WeakPolarHBondContact O-CB 3.14Å; I480-R484 PolarHBondContact O-N 3.48Å; I480-Y525 HydrophobicContact CB-CE1 4.48Å; I480-Y525 HydrophobicContact CD1-CD2 4.1Å; I480-Y525 HydrophobicContact CD1-CG 4.01Å; I480-Y525 HydrophobicContact CG1-CD1 3.97Å; I480-Y525 HydrophobicContact CG1-CD2 4.35Å; I480-Y525 HydrophobicContact CG1-CE1 4.38Å; I480-Y525 HydrophobicContact CG1-CG 3.94Å; I480-Y525 HydrophobicContact CG2-CD1 4.3Å; I480-Y525 HydrophobicContact CG2-CD2 4.25Å; I480-Y525 HydrophobicContact CG2-CE1 3.88Å; I480-Y525 HydrophobicContact CG2-CE2 3.86Å; I480-Y525 HydrophobicContact CG2-CG 4.46Å
481D93.5Very high91.7Very high32 Ų3232.2 Ų32.217%0.17117%0.165CC..Hα-helixtrans-61.1-39.6176.2-85.82.9000111.4K325 H447 D477 I478 I483 R484 E485K325-D481 WeakPolarHBondContact CE-OD2 3.4Å; K325-D481 IonicContact NZ-OD1 3.03Å; K325-D481 PolarHBondContact NZ-OD1 2.9Å; K325-D481 IonicContact NZ-OD2 3.91Å; K325-D481 PolarHBondContact NZ-OD2 3Å; H447-D481 IonicContact CE1-OD1 3.95Å; H447-D481 PolarHBondContact CE1-OD1 3.14Å; H447-D481 IonicContact ND1-OD1 3.65Å; H447-D481 PolarHBondContact ND1-OD1 2.9Å; D477-D481 WeakPolarHBondContact O-CB 3.34Å; D477-D481 PolarHBondContact O-N 3.3Å; I478-D481 PolarHBondContact O-N 3.11Å; D481-I483 VanDerWaalsContact C-N 3.33Å; D481-I483 PolarHBondContact O-N 3.32Å; D481-R484 PolarHBondContact O-N 3.45Å; D481-E485 WeakPolarHBondContact O-CB 3.38Å; D481-E485 PolarHBondContact O-N 2.79Å
482I90.1Very high91.1Very high28 Ų2832.4 Ų32.414%0.14417%0.166CC..Hα-helixtrans-59.2-45.5173.9-67.1164.2000110.7I478 L479 I480 E485 K486 C490I478-I482 HydrophobicContact CG2-CD1 4.22Å; I478-I482 VanDerWaalsContact O-CG1 3.31Å; I478-I482 WeakPolarHBondContact O-CG1 3.37Å; I478-I482 PolarHBondContact O-N 3.41Å; I478-I482 VanDerWaalsContact O-N 3.13Å; L479-I482 PolarHBondContact O-N 3.16Å; I480-I482 VanDerWaalsContact C-N 3.31Å; I480-I482 PolarHBondContact O-N 2.94Å; I482-E485 PolarHBondContact O-N 3.48Å; I482-K486 HydrophobicContact CG2-CD 4.22Å; I482-K486 WeakPolarHBondContact O-CB 3.41Å; I482-K486 PolarHBondContact O-N 3.13Å; I482-C490 HydrophobicContact CG2-CB 4.5Å
483I91.6Very high90.7Very high1 Ų132.9 Ų32.91%0.00517%0.169CC..Hα-helixtrans-69.2-37.7179.9-62.5157.1000111A223 L479 I480 D481 G487 I492 V522 Y525 I526 L529A223-I483 HydrophobicContact CB-CD1 4.48Å; A223-I483 HydrophobicContact CB-CG1 4.14Å; L479-I483 WeakPolarHBondContact O-CD1 3.42Å; L479-I483 WeakPolarHBondContact O-CG1 3.28Å; L479-I483 PolarHBondContact O-N 3.34Å; L479-I483 VanDerWaalsContact O-N 3.16Å; I480-I483 CarbonylContact O-C 3.49Å; I480-I483 PolarHBondContact O-N 3.01Å; I480-I483 VanDerWaalsContact O-N 3.14Å; D481-I483 VanDerWaalsContact C-N 3.33Å; D481-I483 PolarHBondContact O-N 3.32Å; I483-G487 CarbonylContact O-C 3.56Å; I483-G487 WeakPolarHBondContact O-CA 3.1Å; I483-G487 PolarHBondContact O-N 3.26Å; I483-I492 HydrophobicContact CG1-CG2 4.3Å; I483-V522 HydrophobicContact CD1-CG1 3.83Å; I483-Y525 HydrophobicContact CB-CE1 4.14Å; I483-Y525 HydrophobicContact CD1-CD1 4.37Å; I483-Y525 HydrophobicContact CG2-CD1 4.32Å; I483-Y525 HydrophobicContact CG2-CE1 3.82Å; I483-I526 HydrophobicContact CD1-CD1 3.74Å; I483-I526 HydrophobicContact CD1-CG1 3.95Å; I483-I526 HydrophobicContact CG1-CD1 4.47Å; I483-I526 HydrophobicContact CG2-CG1 4.36Å; I483-L529 HydrophobicContact CG2-CD2 3.98Å
484R90.1Very high90.5Very high77 Ų7732.9 Ų32.929%0.29117%0.169SC..Hα-helixtrans-63.7-43.1176.5-169.2-172.4-53.4-95.7-9.2111.3E444 H447 I480 D481E444-R484 IonicContact OE1-CZ 3.7Å; E444-R484 IonicContact OE1-NH1 3.9Å; E444-R484 IonicContact OE1-NH2 2.79Å; E444-R484 PolarHBondContact OE1-NH2 3Å; E444-R484 IonicContact OE2-CZ 2.95Å; E444-R484 IonicContact OE2-NH1 3Å; E444-R484 PolarHBondContact OE2-NH1 3.38Å; E444-R484 IonicContact OE2-NH2 3.37Å; E444-R484 PolarHBondContact OE2-NH2 2.96Å; H447-R484 PolarHBondContact CE1-NE 2.82Å; H447-R484 WeakPolarHBondContact NE2-CD 3.41Å; H447-R484 PolarHBondContact NE2-NE 2.99Å; I480-R484 WeakPolarHBondContact O-CB 3.14Å; I480-R484 PolarHBondContact O-N 3.48Å; D481-R484 PolarHBondContact O-N 3.45Å
485E88.1Confident90.2Very high122 Ų12233.4 Ų33.457%0.5717%0.172SC*.Hα-helixtrans-74.5-41.8-178.4-172.1-176.6174.800112.3D481 I482D481-E485 WeakPolarHBondContact O-CB 3.38Å; D481-E485 PolarHBondContact O-N 2.79Å; I482-E485 PolarHBondContact O-N 3.48Å
486K84.7Confident89.8Confident119 Ų11940 Ų4052%0.51720%0.201SC..Hα-helixtrans-106.6-7.3-169.7-59.5-177.3-175.3175.30114.6I482 C490I482-K486 HydrophobicContact CG2-CD 4.22Å; I482-K486 WeakPolarHBondContact O-CB 3.41Å; I482-K486 PolarHBondContact O-N 3.13Å; K486-C490 HydrophobicContact CB-CB 3.57Å; K486-C490 HydrophobicContact CD-CB 4.21Å
487G83.9Confident89.6Confident30 Ų3040.8 Ų40.831%0.30921%0.206SC..  trans78.9-177.1-174.200000113.8I483 D489 C490I483-G487 CarbonylContact O-C 3.56Å; I483-G487 WeakPolarHBondContact O-CA 3.1Å; I483-G487 PolarHBondContact O-N 3.26Å; G487-D489 VanDerWaalsContact C-N 3.28Å; G487-D489 PolarHBondContact O-N 3.04Å; G487-C490 PolarHBondContact O-N 3.02Å; G487-C490 PolarHBondContact O-SG 2.94Å
488V83.1Confident89.6Confident25 Ų2540.8 Ų40.815%0.15221%0.206CC..THydrogen-bonded Turntrans-72.3-17.5-175.6-63.90000114N222 A223 A224 C490 I526 L529 Q530N222-V488 PolarHBondContact OD1-O 3.13Å; A223-V488 WeakPolarHBondContact CB-O 3.38Å; A224-V488 PolarHBondContact N-O 2.91Å; V488-C490 PolarHBondContact O-N 3.04Å; V488-I526 HydrophobicContact CG1-CG2 4.33Å; V488-L529 HydrophobicContact CG1-CD2 3.89Å; V488-L529 HydrophobicContact CG1-CG 4.46Å; V488-Q530 HydrophobicContact CG1-CG 4.34Å
489D78.3Confident89.4Confident128 Ų12842.5 Ų42.568%0.68421%0.213SC*.THydrogen-bonded Turntrans-86.211.2-179.9-58.6-46.3000112.8N222 G487N222-D489 VanDerWaalsContact ND2-C 3.29Å; N222-D489 PolarHBondContact ND2-O 2.93Å; G487-D489 VanDerWaalsContact C-N 3.28Å; G487-D489 PolarHBondContact O-N 3.04Å
490C82.7Confident89.3Confident10 Ų1044.2 Ų44.27%0.06822%0.222CC..SBendtrans-81.7158179.172.60000113A223 I482 K486 G487 V488A223-C490 WeakPolarHBondContact CB-O 3.35Å; A223-C490 PolarHBondContact N-O 3.36Å; I482-C490 HydrophobicContact CG2-CB 4.5Å; K486-C490 HydrophobicContact CB-CB 3.57Å; K486-C490 HydrophobicContact CD-CB 4.21Å; G487-C490 PolarHBondContact O-N 3.02Å; G487-C490 PolarHBondContact O-SG 2.94Å; V488-C490 PolarHBondContact O-N 3.04Å
491D80.4Confident89.4Confident98 Ų9844.2 Ų44.252%0.52422%0.222SC..EExtended strand (participates in β ladder)trans-80.7133.6171.3-77.9-16.2000111.2R220 I221R220-D491 HydrophobicContact CG-CB 4.22Å; R220-D491 IonicContact NE-OD2 2.82Å; I221-D491 WeakPolarHBondContact O-CA 3.42Å
492I86.3Confident89.5Confident4 Ų443.1 Ų43.12%0.02122%0.216CC..EExtended strand (participates in β ladder)trans-125.2146.1169.759.9174.5000110.6R220 I221 A223 I226 L479 I483 V522R220-I492 WeakPolarHBondContact CA-O 3.34Å; I221-I492 HydrophobicContact CD1-CD1 4.2Å; I221-I492 HydrophobicContact CD1-CG1 4.19Å; I221-I492 HydrophobicContact CG1-CD1 4.38Å; I221-I492 HydrophobicContact CG1-CG1 3.81Å; I221-I492 PolarHBondContact N-O 2.96Å; I221-I492 PolarHBondContact O-N 2.83Å; A223-I492 HydrophobicContact CB-CD1 3.93Å; A223-I492 HydrophobicContact CB-CG1 4.14Å; A223-I492 HydrophobicContact CB-CG2 4.1Å; I226-I492 HydrophobicContact CD1-CD1 4Å; L479-I492 HydrophobicContact CD2-CB 4.32Å; L479-I492 HydrophobicContact CD2-CG2 4.43Å; I483-I492 HydrophobicContact CG1-CG2 4.3Å; I492-V522 HydrophobicContact CD1-CG1 3.88Å
493D89.8Confident89.8Confident10 Ų1042.5 Ų42.55%0.05321%0.214CC..  trans-144.589.1179.4-172.5-19.1000108.4N217 T219 R220 P495 K496 T497N217-D493 PolarHBondContact ND2-OD2 2.98Å; T219-D493 PolarHBondContact OG1-OD1 2.99Å; R220-D493 HydrophobicContact CB-CB 4.19Å; R220-D493 HydrophobicContact CG-CB 4.42Å; D493-P495 WeakPolarHBondContact OD1-CD 3.44Å; D493-K496 HydrophobicContact CB-CB 3.84Å; D493-K496 HydrophobicContact CB-CD 4.36Å; D493-K496 PolarHBondContact O-N 2.84Å; D493-K496 WeakPolarHBondContact OD1-CB 3.4Å; D493-K496 PolarHBondContact OD1-N 2.86Å; D493-K496 WeakPolarHBondContact OD2-CB 3.29Å; D493-T497 PolarHBondContact O-N 2.88Å; D493-T497 PolarHBondContact O-OG1 3.48Å
494V95.1Very high90.1Very high2 Ų242.5 Ų42.51%0.01221%0.214CC..Hα-helixtrans-55.5-53.9-172.8178.90000112.4L479 K496 T497 I498 Y515 I518 Y519L479-V494 HydrophobicContact CD1-CG1 4.45Å; L479-V494 HydrophobicContact CD1-CG2 3.94Å; V494-K496 VanDerWaalsContact C-N 3.3Å; V494-K496 PolarHBondContact O-N 2.86Å; V494-T497 PolarHBondContact O-N 2.66Å; V494-I498 HydrophobicContact CG1-CD1 3.82Å; V494-I498 HydrophobicContact CG1-CG1 4.45Å; V494-I498 WeakPolarHBondContact O-CG1 3.39Å; V494-I498 PolarHBondContact O-N 2.82Å; V494-Y515 HydrophobicContact CG1-CE2 4.22Å; V494-I518 HydrophobicContact CG1-CB 4.48Å; V494-I518 HydrophobicContact CG1-CG2 3.81Å; V494-Y519 HydrophobicContact CB-CD2 4.35Å; V494-Y519 HydrophobicContact CB-CE1 4.38Å; V494-Y519 HydrophobicContact CB-CE2 3.65Å; V494-Y519 HydrophobicContact CG1-CD2 4.06Å; V494-Y519 HydrophobicContact CG1-CE2 3.65Å; V494-Y519 HydrophobicContact CG2-CD1 4.28Å; V494-Y519 HydrophobicContact CG2-CD2 4.23Å; V494-Y519 HydrophobicContact CG2-CE1 3.85Å; V494-Y519 HydrophobicContact CG2-CE2 3.86Å; V494-Y519 HydrophobicContact CG2-CG 4.44Å
495P92.4Very high90.5Very high11 Ų1138.9 Ų38.97%0.07120%0.2CC..Hα-helixtrans-66.7-30.5-179.119.6-25000112.7T219 E250 L254 D493 I498 Q499 Y515T219-P495 HydrophobicContact CG2-CG 3.72Å; E250-P495 HydrophobicContact CG-CG 4.31Å; L254-P495 HydrophobicContact CB-CB 4.34Å; L254-P495 HydrophobicContact CD1-CB 4.32Å; L254-P495 HydrophobicContact CD2-CB 4.21Å; D493-P495 WeakPolarHBondContact OD1-CD 3.44Å; P495-I498 PolarHBondContact O-N 2.83Å; P495-Q499 VanDerWaalsContact O-CB 3.28Å; P495-Q499 WeakPolarHBondContact O-CB 3.35Å; P495-Q499 PolarHBondContact O-N 2.89Å; P495-Y515 HydrophobicContact CB-CE2 4.3Å; P495-Y515 WeakPolarHBondContact CB-OH 3.45Å; P495-Y515 VanDerWaalsContact CD-OH 3.29Å; P495-Y515 WeakPolarHBondContact CD-OH 3.1Å; P495-Y515 VanDerWaalsContact CG-OH 3.28Å; P495-Y515 WeakPolarHBondContact CG-OH 3.36Å
496K89.8Confident90.8Very high138 Ų13833.5 Ų33.560%0.618%0.176SC*.Hα-helixtrans-66.3-42.4172.9-175.3-176.4175.8-167.50111.9D493 V494 Q499 M500D493-K496 HydrophobicContact CB-CB 3.84Å; D493-K496 HydrophobicContact CB-CD 4.36Å; D493-K496 PolarHBondContact O-N 2.84Å; D493-K496 WeakPolarHBondContact OD1-CB 3.4Å; D493-K496 PolarHBondContact OD1-N 2.86Å; D493-K496 WeakPolarHBondContact OD2-CB 3.29Å; V494-K496 VanDerWaalsContact C-N 3.3Å; V494-K496 PolarHBondContact O-N 2.86Å; K496-Q499 PolarHBondContact O-N 2.89Å; K496-M500 WeakPolarHBondContact O-CB 3.26Å; K496-M500 PolarHBondContact O-N 3.26Å
497T95.1Very high91.2Very high16 Ų1628 Ų2810%0.09815%0.153CC..Hα-helixtrans-62.5-44.3174.8-60.70000110.9V475 I478 L479 D493 V494 Q499 M500 V501V475-T497 HydrophobicContact CG1-CG2 4.17Å; I478-T497 HydrophobicContact CB-CG2 4.35Å; I478-T497 HydrophobicContact CG2-CG2 3.8Å; L479-T497 HydrophobicContact CD2-CG2 4.31Å; L479-T497 HydrophobicContact CG-CG2 4.38Å; D493-T497 PolarHBondContact O-N 2.88Å; D493-T497 PolarHBondContact O-OG1 3.48Å; V494-T497 PolarHBondContact O-N 2.66Å; T497-Q499 PolarHBondContact O-N 2.82Å; T497-M500 HydrophobicContact CG2-CE 4.24Å; T497-M500 WeakPolarHBondContact O-CB 3.4Å; T497-M500 PolarHBondContact O-N 3.4Å; T497-V501 WeakPolarHBondContact O-CG2 3.48Å; T497-V501 PolarHBondContact O-N 3.03Å
498I97Very high91.8Very high0 Ų026.6 Ų26.60%014%0.138CC..Hα-helixtrans-62.9-44.5176-63.4167.6000110.9L254 V475 V494 P495 M500 V501 R502 V509 Y515 I518L254-I498 HydrophobicContact CD2-CB 3.97Å; L254-I498 HydrophobicContact CD2-CD1 4.22Å; L254-I498 HydrophobicContact CD2-CG2 3.72Å; V475-I498 HydrophobicContact CB-CG1 4.42Å; V475-I498 HydrophobicContact CG1-CG1 3.76Å; V475-I498 HydrophobicContact CG2-CG1 3.94Å; V494-I498 HydrophobicContact CG1-CD1 3.82Å; V494-I498 HydrophobicContact CG1-CG1 4.45Å; V494-I498 WeakPolarHBondContact O-CG1 3.39Å; V494-I498 PolarHBondContact O-N 2.82Å; P495-I498 PolarHBondContact O-N 2.83Å; I498-M500 VanDerWaalsContact C-N 3.27Å; I498-M500 PolarHBondContact O-N 2.89Å; I498-V501 PolarHBondContact O-N 3.33Å; I498-R502 HydrophobicContact CG2-CG 4.13Å; I498-R502 WeakPolarHBondContact O-CB 3.49Å; I498-R502 WeakPolarHBondContact O-CG 3.17Å; I498-R502 PolarHBondContact O-N 2.88Å; I498-V509 HydrophobicContact CD1-CG1 4.47Å; I498-V509 HydrophobicContact CD1-CG2 4.29Å; I498-V509 HydrophobicContact CG1-CG2 4.19Å; I498-V509 HydrophobicContact CG2-CB 4.15Å; I498-V509 HydrophobicContact CG2-CG2 4.14Å; I498-Y515 HydrophobicContact CD1-CD2 3.43Å; I498-Y515 VanDerWaalsContact CD1-CD2 3.43Å; I498-Y515 HydrophobicContact CD1-CE2 3.5Å; I498-I518 HydrophobicContact CD1-CD1 3.87Å; I498-I518 HydrophobicContact CG1-CD1 4.41Å
499Q93.5Very high92.5Very high41 Ų4125.4 Ų25.419%0.19213%0.131CC..Hα-helixtrans-60.3-38.6177.6-173.167.75.800111.7L254 P495 K496 T497 R502 S503L254-Q499 HydrophobicContact CD1-CB 3.89Å; L254-Q499 VanDerWaalsContact CD1-OE1 3.29Å; P495-Q499 VanDerWaalsContact O-CB 3.28Å; P495-Q499 WeakPolarHBondContact O-CB 3.35Å; P495-Q499 PolarHBondContact O-N 2.89Å; K496-Q499 PolarHBondContact O-N 2.89Å; T497-Q499 PolarHBondContact O-N 2.82Å; Q499-R502 PolarHBondContact O-N 2.88Å; Q499-S503 PolarHBondContact O-N 2.8Å
500M94.4Very high93.3Very high36 Ų3619.4 Ų19.418%0.17710%0.099CC..Hα-helixtrans-63.1-46.4174.7175.1-77.3-67.400111.2P312 I478 K496 T497 I498 R502 S503 Q504P312-M500 VanDerWaalsContact O-CE 3.25Å; P312-M500 WeakPolarHBondContact O-CE 3.47Å; I478-M500 HydrophobicContact CD1-CE 4.21Å; K496-M500 WeakPolarHBondContact O-CB 3.26Å; K496-M500 PolarHBondContact O-N 3.26Å; T497-M500 HydrophobicContact CG2-CE 4.24Å; T497-M500 WeakPolarHBondContact O-CB 3.4Å; T497-M500 PolarHBondContact O-N 3.4Å; I498-M500 VanDerWaalsContact C-N 3.27Å; I498-M500 PolarHBondContact O-N 2.89Å; M500-R502 PolarHBondContact O-N 3.1Å; M500-S503 WeakPolarHBondContact O-CB 3.39Å; M500-S503 PolarHBondContact O-N 3.44Å; M500-S503 PolarHBondContact O-OG 2.95Å; M500-Q504 PolarHBondContact O-NE2 3.26Å; M500-Q504 PolarHBondContact SD-NE2 3.17Å
501V97.2Very high93.8Very high0 Ų019.7 Ų19.70%010%0.1CC..Hα-helixtrans-65.5-39.4176.5174.80000111.3I310 V475 I478 T497 I498 S503 Q504 R505 M508I310-V501 HydrophobicContact CG2-CB 4.39Å; I310-V501 HydrophobicContact CG2-CG1 3.88Å; I310-V501 HydrophobicContact CG2-CG2 4.06Å; V475-V501 HydrophobicContact CG2-CB 4.38Å; V475-V501 HydrophobicContact CG2-CG2 4.07Å; I478-V501 HydrophobicContact CD1-CG2 3.82Å; T497-V501 WeakPolarHBondContact O-CG2 3.48Å; T497-V501 PolarHBondContact O-N 3.03Å; I498-V501 PolarHBondContact O-N 3.33Å; V501-S503 PolarHBondContact O-N 3.06Å; V501-Q504 PolarHBondContact O-N 3.48Å; V501-R505 PolarHBondContact O-N 2.83Å; V501-M508 HydrophobicContact CG1-CB 3.72Å; V501-M508 HydrophobicContact CG1-CE 3.46Å; V501-M508 VanDerWaalsContact CG1-CE 3.46Å; V501-M508 HydrophobicContact CG1-CG 3.75Å; V501-M508 HydrophobicContact CG1-SD 4.49Å
502R96.9Very high94.5Very high10 Ų1017.8 Ų17.84%0.0389%0.088CC..Hα-helixtrans-63-23.3174.9-77.4179.9176.3-172.2-2.5113.7L261 F285 I498 Q499 M500 Q504 R505 M508 V509L261-R502 HydrophobicContact CD1-CB 3.74Å; F285-R502 WeakPolarHBondContact CE2-O 3.34Å; I498-R502 HydrophobicContact CG2-CG 4.13Å; I498-R502 WeakPolarHBondContact O-CB 3.49Å; I498-R502 WeakPolarHBondContact O-CG 3.17Å; I498-R502 PolarHBondContact O-N 2.88Å; Q499-R502 PolarHBondContact O-N 2.88Å; M500-R502 PolarHBondContact O-N 3.1Å; R502-Q504 PolarHBondContact O-N 2.75Å; R502-R505 CarbonylContact C-O 3.43Å; R502-R505 WeakPolarHBondContact CA-O 3.45Å; R502-M508 HydrophobicContact CG-CB 3.96Å; R502-M508 WeakPolarHBondContact CG-O 3.37Å; R502-M508 PolarHBondContact NE-O 3.05Å; R502-V509 PolarHBondContact NH2-O 3.38Å
503S95.8Very high94.8Very high15 Ų1519.3 Ų19.311%0.10510%0.101CC..THydrogen-bonded Turntrans-73.3-13.2174.976.60000113.3Y263 H287 Q499 M500 V501Y263-S503 WeakPolarHBondContact CE2-O 3.49Å; H287-S503 PolarHBondContact CE1-O 3.26Å; H287-S503 PolarHBondContact NE2-O 3.1Å; H287-S503 VanDerWaalsContact NE2-O 3.1Å; Q499-S503 PolarHBondContact O-N 2.8Å; M500-S503 WeakPolarHBondContact O-CB 3.39Å; M500-S503 PolarHBondContact O-N 3.44Å; M500-S503 PolarHBondContact O-OG 2.95Å; V501-S503 PolarHBondContact O-N 3.06Å
504Q97.9Very high95.2Very high1 Ų118.9 Ų18.91%0.00510%0.099CC..THydrogen-bonded Turntrans-110.5-23.3-176.3-60.2177.178.300112.6T288 N308 I310 M311 M500 V501 R502T288-Q504 HydrophobicContact CG2-CB 4.11Å; T288-Q504 HydrophobicContact CG2-CG 4.18Å; T288-Q504 PolarHBondContact OG1-O 3.45Å; N308-Q504 WeakPolarHBondContact CB-O 3.33Å; N308-Q504 PolarHBondContact ND2-O 3.46Å; I310-Q504 HydrophobicContact CD1-CB 3.7Å; M311-Q504 PolarHBondContact O-NE2 3.46Å; M500-Q504 PolarHBondContact O-NE2 3.26Å; M500-Q504 PolarHBondContact SD-NE2 3.17Å; V501-Q504 PolarHBondContact O-N 3.48Å; R502-Q504 PolarHBondContact O-N 2.75Å
505R98.3Very high95.3Very high1 Ų118.8 Ų18.80%0.00410%0.098CC..SBendtrans-149.6136.8167.3-176.9170.3176.982.5-1.7110.1F285 N306 N308 I310 A465 G466 I467 V501 R502 M508F285-R505 VanDerWaalsContact CE2-C 3.49Å; N306-R505 PolarHBondContact OD1-NH1 3.35Å; N306-R505 VanDerWaalsContact OD1-NH1 3.09Å; N306-R505 PolarHBondContact OD1-NH2 3.24Å; N308-R505 HydrophobicContact CB-CB 4.02Å; N308-R505 HydrophobicContact CB-CG 4.43Å; N308-R505 WeakPolarHBondContact OD1-CG 3.38Å; N308-R505 PolarHBondContact OD1-NH1 3.46Å; I310-R505 HydrophobicContact CD1-CB 3.89Å; A465-R505 PolarHBondContact O-NH2 3.12Å; G466-R505 PolarHBondContact O-NE 2.88Å; I467-R505 HydrophobicContact CG2-CG 4.33Å; V501-R505 PolarHBondContact O-N 2.83Å; R502-R505 CarbonylContact C-O 3.43Å; R502-R505 WeakPolarHBondContact CA-O 3.45Å; R505-M508 HydrophobicContact CB-CG 3.93Å; R505-M508 HydrophobicContact CB-SD 4.11Å; R505-M508 HydrophobicContact CG-CG 4.38Å; R505-M508 HydrophobicContact CG-SD 4.16Å; R505-M508 WeakPolarHBondContact O-CG 3.27Å
506S94.3Very high95.4Very high9 Ų922.9 Ų22.96%0.06311%0.113CC..THydrogen-bonded Turntrans-64.3143.5-176.8-168.80000112.4E76 F285 I467 M508E76-S506 VanDerWaalsContact CD-OG 3.3Å; E76-S506 WeakPolarHBondContact OE1-CB 3.38Å; E76-S506 PolarHBondContact OE1-OG 3.38Å; F285-S506 VanDerWaalsContact CE2-N 3.26Å; I467-S506 WeakPolarHBondContact CG2-O 3.32Å; S506-M508 VanDerWaalsContact C-N 3.31Å; S506-M508 PolarHBondContact O-N 3.44Å
507G92.7Very high95.8Very high3 Ų316.7 Ų16.73%0.0319%0.086CC..THydrogen-bonded Turntrans69.618.317000000115.7V509 Q510G507-V509 PolarHBondContact O-N 2.9Å; G507-Q510 PolarHBondContact O-NE2 3.32Å
508M98.1Very high95.9Very high0 Ų016 Ų160%08%0.081CC..SBendtrans-60.8125.6177.2-64.6-71.3-80.300110.6I310 A329 I467 T470 G471 I474 V501 R502 R505 S506I310-M508 HydrophobicContact CD1-CE 4.46Å; I310-M508 HydrophobicContact CG1-CE 4.48Å; A329-M508 HydrophobicContact CB-CE 3.9Å; A329-M508 HydrophobicContact CB-SD 4.37Å; I467-M508 HydrophobicContact CB-SD 4.48Å; I467-M508 WeakPolarHBondContact O-CA 3.38Å; T470-M508 HydrophobicContact CG2-CE 4.43Å; G471-M508 VanDerWaalsContact CA-CE 3.44Å; I474-M508 HydrophobicContact CD1-CE 3.96Å; V501-M508 HydrophobicContact CG1-CB 3.72Å; V501-M508 HydrophobicContact CG1-CE 3.46Å; V501-M508 VanDerWaalsContact CG1-CE 3.46Å; V501-M508 HydrophobicContact CG1-CG 3.75Å; V501-M508 HydrophobicContact CG1-SD 4.49Å; R502-M508 HydrophobicContact CG-CB 3.96Å; R502-M508 WeakPolarHBondContact CG-O 3.37Å; R502-M508 PolarHBondContact NE-O 3.05Å; R505-M508 HydrophobicContact CB-CG 3.93Å; R505-M508 HydrophobicContact CB-SD 4.11Å; R505-M508 HydrophobicContact CG-CG 4.38Å; R505-M508 HydrophobicContact CG-SD 4.16Å; R505-M508 WeakPolarHBondContact O-CG 3.27Å; S506-M508 VanDerWaalsContact C-N 3.31Å; S506-M508 PolarHBondContact O-N 3.44Å
509V97.8Very high96Very high0 Ų016 Ų160%08%0.081CC..SBendtrans64.6108.3-166.3-172.10000111.5I467 V475 I498 R502 G507 Q514 I518I467-V509 PolarHBondContact O-N 3.42Å; V475-V509 HydrophobicContact CG2-CG2 4.2Å; I498-V509 HydrophobicContact CD1-CG1 4.47Å; I498-V509 HydrophobicContact CD1-CG2 4.29Å; I498-V509 HydrophobicContact CG1-CG2 4.19Å; I498-V509 HydrophobicContact CG2-CB 4.15Å; I498-V509 HydrophobicContact CG2-CG2 4.14Å; R502-V509 PolarHBondContact NH2-O 3.38Å; G507-V509 PolarHBondContact O-N 2.9Å; V509-Q514 HydrophobicContact CG1-CB 3.93Å; V509-I518 HydrophobicContact CG1-CD1 4.02Å; V509-I518 HydrophobicContact CG2-CD1 3.78Å
510Q94.2Very high96.1Very high2 Ų217 Ų171%0.0099%0.087CC..  trans-96.2-31.2-166.1-79.1-70.4-73.200115.1N58 G60 Y62 Y63 A72 I467 G507N58-Q510 PolarHBondContact ND2-O 2.94Å; G60-Q510 WeakPolarHBondContact O-CB 3.28Å; Y62-Q510 VanDerWaalsContact CA-OE1 3.22Å; Y63-Q510 PolarHBondContact OH-O 2.88Å; A72-Q510 PolarHBondContact O-NE2 2.82Å; A72-Q510 PolarHBondContact O-OE1 2.87Å; I467-Q510 HydrophobicContact CD1-CG 4.18Å; I467-Q510 HydrophobicContact CG1-CG 3.98Å; G507-Q510 PolarHBondContact O-NE2 3.32Å
511T93.8Very high96.3Very high17 Ų1715.3 Ų15.310%0.1048%0.078CC..SBendtrans-130.9157.6-169.955.80000112.2N58 A513 Q514 Y515N58-T511 HydrophobicContact CB-CG2 4.46Å; N58-T511 WeakPolarHBondContact OD1-CG2 3.42Å; T511-A513 VanDerWaalsContact C-N 3.26Å; T511-A513 PolarHBondContact O-N 3.5Å; T511-Q514 WeakPolarHBondContact O-CB 3.45Å; T511-Q514 PolarHBondContact O-N 2.99Å; T511-Q514 WeakPolarHBondContact OG1-CG 3.4Å; T511-Q514 PolarHBondContact OG1-N 3.07Å; T511-Y515 PolarHBondContact O-N 3Å
512E93.4Very high96.3Very high57 Ų5715.3 Ų15.327%0.2668%0.078SC..Hα-helixtrans-60-36.9172.5179.5-81145.200111.5F247 W248 F251 Q514 Y515 R516F247-E512 HydrophobicContact CB-CG 4.46Å; F247-E512 WeakPolarHBondContact CB-OE1 3.25Å; W248-E512 HydrophobicContact CB-CG 4.35Å; F251-E512 HydrophobicContact CB-CG 4.45Å; F251-E512 HydrophobicContact CD1-CB 3.82Å; F251-E512 HydrophobicContact CE1-CB 4.34Å; F251-E512 HydrophobicContact CG-CB 4.25Å; E512-Q514 VanDerWaalsContact C-N 3.32Å; E512-Q514 PolarHBondContact O-N 3.14Å; E512-Y515 CarbonylContact O-C 3.46Å; E512-Y515 WeakPolarHBondContact O-CA 3.34Å; E512-Y515 VanDerWaalsContact O-CB 3.3Å; E512-Y515 WeakPolarHBondContact O-CB 3.29Å; E512-Y515 PolarHBondContact O-N 3.44Å; E512-R516 WeakPolarHBondContact O-CB 3.3Å; E512-R516 PolarHBondContact O-N 3.29Å
513A94.1Very high96.3Very high36 Ų3616 Ų1630%0.2988%0.082SC..Hα-helixtrans-58.3-42.2174.900000112.7V432 T511 F517V432-A513 HydrophobicContact CG1-CB 4.39Å; V432-A513 HydrophobicContact CG2-CB 4.44Å; T511-A513 VanDerWaalsContact C-N 3.26Å; T511-A513 PolarHBondContact O-N 3.5Å; A513-F517 VanDerWaalsContact O-CB 3.31Å; A513-F517 WeakPolarHBondContact O-CB 3.4Å; A513-F517 PolarHBondContact O-N 2.88Å
514Q96.9Very high96.3Very high1 Ų118.1 Ų18.11%0.0059%0.09CC..Hα-helixtrans-66.8-39.9173.4-75167.5-7.800112.1G60 V432 T472 V509 T511 E512 F517 I518G60-Q514 PolarHBondContact O-NE2 3.11Å; V432-Q514 HydrophobicContact CG1-CB 4.29Å; V432-Q514 HydrophobicContact CG1-CG 3.71Å; T472-Q514 WeakPolarHBondContact OG1-CB 3.27Å; V509-Q514 HydrophobicContact CG1-CB 3.93Å; T511-Q514 WeakPolarHBondContact O-CB 3.45Å; T511-Q514 PolarHBondContact O-N 2.99Å; T511-Q514 WeakPolarHBondContact OG1-CG 3.4Å; T511-Q514 PolarHBondContact OG1-N 3.07Å; E512-Q514 VanDerWaalsContact C-N 3.32Å; E512-Q514 PolarHBondContact O-N 3.14Å; Q514-F517 PolarHBondContact O-N 2.75Å; Q514-I518 WeakPolarHBondContact O-CG1 3.28Å; Q514-I518 PolarHBondContact O-N 3.41Å; Q514-I518 VanDerWaalsContact O-N 3.09Å
515Y97Very high96.3Very high0 Ų018.6 Ų18.60%09%0.092CC..Hα-helixtrans-60.4-50176.2-173.8-97.2000111.9F247 E250 F251 L254 V494 P495 I498 T511 E512 F517 I518 Y519F247-Y515 HydrophobicContact CD1-CD1 4.1Å; F247-Y515 HydrophobicContact CD1-CE1 4.23Å; E250-Y515 HydrophobicContact CB-CE1 4.34Å; E250-Y515 HydrophobicContact CG-CE1 4.4Å; E250-Y515 WeakPolarHBondContact CG-OH 3.38Å; E250-Y515 VanDerWaalsContact OE1-CE1 3.29Å; E250-Y515 WeakPolarHBondContact OE1-CE1 3.31Å; E250-Y515 VanDerWaalsContact OE1-CZ 3.27Å; E250-Y515 PolarHBondContact OE1-OH 2.94Å; F251-Y515 HydrophobicContact CB-CD1 4.05Å; F251-Y515 HydrophobicContact CB-CE1 4.41Å; F251-Y515 HydrophobicContact CB-CG 4.14Å; F251-Y515 HydrophobicContact CD2-CD1 4.34Å; F251-Y515 AromaticContact CD2-CD2 3.54Å; F251-Y515 HydrophobicContact CD2-CD2 3.54Å; F251-Y515 HydrophobicContact CD2-CE2 4.25Å; F251-Y515 AromaticContact CD2-CG 3.58Å; F251-Y515 HydrophobicContact CD2-CG 3.58Å; F251-Y515 HydrophobicContact CE2-CD2 4.22Å; F251-Y515 HydrophobicContact CE2-CG 4.38Å; F251-Y515 HydrophobicContact CG-CD2 4.5Å; F251-Y515 HydrophobicContact CG-CG 4.21Å; L254-Y515 HydrophobicContact CD2-CD2 4.39Å; L254-Y515 HydrophobicContact CD2-CE2 3.98Å; V494-Y515 HydrophobicContact CG1-CE2 4.22Å; P495-Y515 HydrophobicContact CB-CE2 4.3Å; P495-Y515 WeakPolarHBondContact CB-OH 3.45Å; P495-Y515 VanDerWaalsContact CD-OH 3.29Å; P495-Y515 WeakPolarHBondContact CD-OH 3.1Å; P495-Y515 VanDerWaalsContact CG-OH 3.28Å; P495-Y515 WeakPolarHBondContact CG-OH 3.36Å; I498-Y515 HydrophobicContact CD1-CD2 3.43Å; I498-Y515 VanDerWaalsContact CD1-CD2 3.43Å; I498-Y515 HydrophobicContact CD1-CE2 3.5Å; T511-Y515 PolarHBondContact O-N 3Å; E512-Y515 CarbonylContact O-C 3.46Å; E512-Y515 WeakPolarHBondContact O-CA 3.34Å; E512-Y515 VanDerWaalsContact O-CB 3.3Å; E512-Y515 WeakPolarHBondContact O-CB 3.29Å; E512-Y515 PolarHBondContact O-N 3.44Å; Y515-F517 VanDerWaalsContact C-N 3.31Å; Y515-F517 PolarHBondContact O-N 2.96Å; Y515-I518 WeakPolarHBondContact O-CB 3.34Å; Y515-I518 PolarHBondContact O-N 2.82Å; Y515-Y519 HydrophobicContact CD1-CD2 4.37Å; Y515-Y519 HydrophobicContact CD1-CE2 4.19Å; Y515-Y519 HydrophobicContact CE1-CD2 4.1Å; Y515-Y519 AromaticContact CE1-CE2 3.49Å; Y515-Y519 HydrophobicContact CE1-CE2 3.49Å; Y515-Y519 VanDerWaalsContact CE1-CE2 3.49Å; Y515-Y519 HydrophobicContact CE2-CE2 4.48Å; Y515-Y519 AromaticContact CZ-CE2 3.67Å; Y515-Y519 PolarHBondContact O-N 3.31Å
516R95.5Very high96Very high98 Ų9818.7 Ų18.737%0.379%0.092SC..Hα-helixtrans-58.3-42.9173.4-176.6-178.8-177.3115.89.3111.5S234 F247 E512 I518 Y519 M520S234-R516 PolarHBondContact OG-NH2 2.9Å; F247-R516 HydrophobicContact CD1-CB 4.16Å; F247-R516 HydrophobicContact CD1-CG 4.29Å; F247-R516 HydrophobicContact CD2-CG 3.96Å; F247-R516 HydrophobicContact CE1-CB 4.45Å; F247-R516 HydrophobicContact CE1-CG 4.27Å; F247-R516 HydrophobicContact CE2-CG 3.94Å; F247-R516 HydrophobicContact CG-CB 4.2Å; F247-R516 HydrophobicContact CG-CG 4.13Å; F247-R516 HydrophobicContact CZ-CG 4.09Å; E512-R516 WeakPolarHBondContact O-CB 3.3Å; E512-R516 PolarHBondContact O-N 3.29Å; R516-I518 VanDerWaalsContact C-N 3.28Å; R516-I518 PolarHBondContact O-N 2.84Å; R516-Y519 WeakPolarHBondContact O-CB 3.43Å; R516-Y519 PolarHBondContact O-N 2.87Å; R516-Y519 VanDerWaalsContact O-N 3.15Å; R516-M520 HydrophobicContact CG-CG 4.41Å; R516-M520 WeakPolarHBondContact O-CG 3.35Å; R516-M520 PolarHBondContact O-N 3.45Å
517F97.5Very high96Very high8 Ų821.6 Ų21.64%0.03511%0.105CC..Hα-helixtrans-60.4-35.6178.8-174.1-100.4000113W427 V432 P433 P436 V439 T472 I476 A513 Q514 Y515 Y519 M520 A521W427-F517 HydrophobicContact CH2-CE1 4.3Å; V432-F517 HydrophobicContact CB-CB 3.99Å; V432-F517 HydrophobicContact CB-CD2 3.89Å; V432-F517 HydrophobicContact CB-CG 3.93Å; V432-F517 HydrophobicContact CG1-CB 3.85Å; V432-F517 HydrophobicContact CG1-CG 4.16Å; V432-F517 HydrophobicContact CG2-CB 4.09Å; V432-F517 HydrophobicContact CG2-CD2 4.03Å; V432-F517 HydrophobicContact CG2-CG 4.3Å; P433-F517 HydrophobicContact CB-CE2 3.92Å; P433-F517 HydrophobicContact CB-CZ 4.06Å; P433-F517 HydrophobicContact CG-CE2 4.25Å; P433-F517 HydrophobicContact CG-CZ 4Å; P433-F517 VanDerWaalsContact O-CE2 3.3Å; P433-F517 WeakPolarHBondContact O-CE2 3.36Å; P436-F517 HydrophobicContact CB-CE2 4.11Å; P436-F517 HydrophobicContact CB-CZ 4.11Å; V439-F517 HydrophobicContact CB-CE1 4.44Å; V439-F517 HydrophobicContact CB-CZ 4.23Å; V439-F517 HydrophobicContact CG1-CE1 4.39Å; V439-F517 HydrophobicContact CG2-CE1 4.21Å; V439-F517 HydrophobicContact CG2-CZ 3.87Å; T472-F517 HydrophobicContact CG2-CD1 3.99Å; I476-F517 HydrophobicContact CD1-CD1 3.99Å; I476-F517 HydrophobicContact CD1-CE1 3.95Å; A513-F517 VanDerWaalsContact O-CB 3.31Å; A513-F517 WeakPolarHBondContact O-CB 3.4Å; A513-F517 PolarHBondContact O-N 2.88Å; Q514-F517 PolarHBondContact O-N 2.75Å; Y515-F517 VanDerWaalsContact C-N 3.31Å; Y515-F517 PolarHBondContact O-N 2.96Å; F517-Y519 PolarHBondContact O-N 2.67Å; F517-M520 PolarHBondContact O-N 2.84Å; F517-A521 WeakPolarHBondContact O-CB 3.45Å; F517-A521 PolarHBondContact O-N 3.24Å
518I98.6Very high96Very high0 Ų022.6 Ų22.60%011%0.111CC..Hα-helixtrans-59.9-47.3174.7-65.6161.9000110.4T472 V475 I476 L479 V494 I498 V509 Q514 Y515 R516 A521 V522T472-I518 HydrophobicContact CG2-CD1 4.45Å; T472-I518 HydrophobicContact CG2-CG1 3.92Å; V475-I518 HydrophobicContact CB-CD1 4.22Å; V475-I518 HydrophobicContact CG1-CD1 3.96Å; V475-I518 HydrophobicContact CG1-CG2 3.95Å; I476-I518 HydrophobicContact CD1-CG1 4.34Å; I476-I518 HydrophobicContact CG1-CB 4.22Å; I476-I518 HydrophobicContact CG1-CG1 3.93Å; I476-I518 HydrophobicContact CG1-CG2 4.13Å; L479-I518 HydrophobicContact CD1-CG2 3.7Å; V494-I518 HydrophobicContact CG1-CB 4.48Å; V494-I518 HydrophobicContact CG1-CG2 3.81Å; I498-I518 HydrophobicContact CD1-CD1 3.87Å; I498-I518 HydrophobicContact CG1-CD1 4.41Å; V509-I518 HydrophobicContact CG1-CD1 4.02Å; V509-I518 HydrophobicContact CG2-CD1 3.78Å; Q514-I518 WeakPolarHBondContact O-CG1 3.28Å; Q514-I518 PolarHBondContact O-N 3.41Å; Q514-I518 VanDerWaalsContact O-N 3.09Å; Y515-I518 WeakPolarHBondContact O-CB 3.34Å; Y515-I518 PolarHBondContact O-N 2.82Å; R516-I518 VanDerWaalsContact C-N 3.28Å; R516-I518 PolarHBondContact O-N 2.84Å; I518-A521 PolarHBondContact O-N 3.43Å; I518-V522 WeakPolarHBondContact O-CG2 3.17Å; I518-V522 PolarHBondContact O-N 3.19Å
519Y97.4Very high95.5Very high1 Ų124.3 Ų24.30%0.00412%0.12CC..Hα-helixtrans-61.2-46176.8-86.2-91.7000112.3I226 R229 V230 L233 F247 E250 V494 Y515 R516 F517 A521 V522 Q523I226-Y519 HydrophobicContact CD1-CD1 3.59Å; I226-Y519 HydrophobicContact CD1-CE1 4.01Å; R229-Y519 HydrophobicContact CG-CE1 4.09Å; V230-Y519 HydrophobicContact CG2-CD1 4.13Å; L233-Y519 HydrophobicContact CD1-CD1 4.28Å; L233-Y519 HydrophobicContact CD1-CE1 3.88Å; L233-Y519 HydrophobicContact CD1-CE2 4.34Å; F247-Y519 HydrophobicContact CD1-CD2 4.16Å; F247-Y519 HydrophobicContact CE1-CD1 4.2Å; F247-Y519 AromaticContact CE1-CD2 3.56Å; F247-Y519 HydrophobicContact CE1-CD2 3.56Å; F247-Y519 HydrophobicContact CE1-CE2 4.16Å; F247-Y519 AromaticContact CE1-CG 3.57Å; F247-Y519 HydrophobicContact CE1-CG 3.57Å; F247-Y519 HydrophobicContact CZ-CG 4.27Å; E250-Y519 WeakPolarHBondContact OE1-CE2 3.38Å; E250-Y519 VanDerWaalsContact OE1-CZ 3.31Å; E250-Y519 PolarHBondContact OE1-OH 3.05Å; E250-Y519 PolarHBondContact OE2-OH 3Å; V494-Y519 HydrophobicContact CB-CD2 4.35Å; V494-Y519 HydrophobicContact CB-CE1 4.38Å; V494-Y519 HydrophobicContact CB-CE2 3.65Å; V494-Y519 HydrophobicContact CG1-CD2 4.06Å; V494-Y519 HydrophobicContact CG1-CE2 3.65Å; V494-Y519 HydrophobicContact CG2-CD1 4.28Å; V494-Y519 HydrophobicContact CG2-CD2 4.23Å; V494-Y519 HydrophobicContact CG2-CE1 3.85Å; V494-Y519 HydrophobicContact CG2-CE2 3.86Å; V494-Y519 HydrophobicContact CG2-CG 4.44Å; Y515-Y519 HydrophobicContact CD1-CD2 4.37Å; Y515-Y519 HydrophobicContact CD1-CE2 4.19Å; Y515-Y519 HydrophobicContact CE1-CD2 4.1Å; Y515-Y519 AromaticContact CE1-CE2 3.49Å; Y515-Y519 HydrophobicContact CE1-CE2 3.49Å; Y515-Y519 VanDerWaalsContact CE1-CE2 3.49Å; Y515-Y519 HydrophobicContact CE2-CE2 4.48Å; Y515-Y519 AromaticContact CZ-CE2 3.67Å; Y515-Y519 PolarHBondContact O-N 3.31Å; R516-Y519 WeakPolarHBondContact O-CB 3.43Å; R516-Y519 PolarHBondContact O-N 2.87Å; R516-Y519 VanDerWaalsContact O-N 3.15Å; F517-Y519 PolarHBondContact O-N 2.67Å; Y519-A521 VanDerWaalsContact C-N 3.31Å; Y519-A521 PolarHBondContact O-N 3.24Å; Y519-V522 PolarHBondContact O-N 2.89Å; Y519-Q523 WeakPolarHBondContact O-CB 3.38Å; Y519-Q523 PolarHBondContact O-N 3.26Å
520M97Very high95Very high63 Ų6327.6 Ų27.631%0.3114%0.135SC..Hα-helixtrans-61.4-40.3177.8-64.1-58.2-54.900111.8V230 R516 F517 Q523 H524V230-M520 HydrophobicContact CG1-SD 3.8Å; R516-M520 HydrophobicContact CG-CG 4.41Å; R516-M520 WeakPolarHBondContact O-CG 3.35Å; R516-M520 PolarHBondContact O-N 3.45Å; F517-M520 PolarHBondContact O-N 2.84Å; M520-Q523 PolarHBondContact O-N 3.2Å; M520-H524 WeakPolarHBondContact O-CB 3.45Å; M520-H524 PolarHBondContact O-N 3.27Å
521A98Very high94.7Very high0 Ų033.9 Ų33.90%016%0.158CC..Hα-helixtrans-66.5-44.7177.800000111.9P436 L440 I476 F517 I518 Y519 H524 Y525P436-A521 HydrophobicContact CB-CB 3.87Å; L440-A521 WeakPolarHBondContact CD1-O 3.39Å; L440-A521 HydrophobicContact CD2-CB 4.18Å; I476-A521 HydrophobicContact CD1-CB 3.83Å; I476-A521 HydrophobicContact CG1-CB 4.18Å; I476-A521 HydrophobicContact CG2-CB 4.1Å; F517-A521 WeakPolarHBondContact O-CB 3.45Å; F517-A521 PolarHBondContact O-N 3.24Å; I518-A521 PolarHBondContact O-N 3.43Å; Y519-A521 VanDerWaalsContact C-N 3.31Å; Y519-A521 PolarHBondContact O-N 3.24Å; A521-H524 PolarHBondContact O-N 3.4Å; A521-Y525 WeakPolarHBondContact O-CB 3.15Å; A521-Y525 PolarHBondContact O-N 2.81Å
522V97.3Very high94.4Very high0 Ų038.2 Ų38.20%017%0.173CC..Hα-helixtrans-64.2-42.4176.3174.40000111I226 L479 I483 I492 I518 Y519 Y525 I526I226-V522 HydrophobicContact CD1-CG1 4.44Å; I226-V522 HydrophobicContact CG1-CG1 4.23Å; L479-V522 HydrophobicContact CB-CG2 3.95Å; L479-V522 HydrophobicContact CD1-CG2 3.91Å; I483-V522 HydrophobicContact CD1-CG1 3.83Å; I492-V522 HydrophobicContact CD1-CG1 3.88Å; I518-V522 WeakPolarHBondContact O-CG2 3.17Å; I518-V522 PolarHBondContact O-N 3.19Å; Y519-V522 PolarHBondContact O-N 2.89Å; V522-Y525 PolarHBondContact O-N 3.08Å; V522-I526 HydrophobicContact CG1-CD1 4Å; V522-I526 WeakPolarHBondContact O-CG1 3.14Å; V522-I526 PolarHBondContact O-N 3.36Å
523Q96.5Very high94Very high25 Ų2538.8 Ų38.812%0.11718%0.177CC..Hα-helixtrans-56.4-54.8174.1179.3-171-12.200111.4I226 V230 Y519 M520 Y525 I526 E527I226-Q523 HydrophobicContact CG1-CB 4.15Å; I226-Q523 HydrophobicContact CG2-CB 4.12Å; I226-Q523 HydrophobicContact CG2-CG 4.29Å; V230-Q523 VanDerWaalsContact CG1-OE1 3.31Å; V230-Q523 HydrophobicContact CG2-CB 4.45Å; Y519-Q523 WeakPolarHBondContact O-CB 3.38Å; Y519-Q523 PolarHBondContact O-N 3.26Å; M520-Q523 PolarHBondContact O-N 3.2Å; Q523-Y525 VanDerWaalsContact C-N 3.28Å; Q523-Y525 PolarHBondContact O-N 2.87Å; Q523-I526 PolarHBondContact O-N 2.78Å; Q523-I526 VanDerWaalsContact O-N 3.13Å; Q523-E527 HydrophobicContact CG-CG 4.47Å; Q523-E527 VanDerWaalsContact CG-OE1 3.31Å; Q523-E527 WeakPolarHBondContact CG-OE1 3.33Å; Q523-E527 PolarHBondContact NE2-OE1 2.84Å; Q523-E527 WeakPolarHBondContact O-CG 3.43Å; Q523-E527 PolarHBondContact O-N 2.71Å
524H96.8Very high93.6Very high58 Ų5842.1 Ų42.127%0.26919%0.186SC..Hα-helixtrans-62.1-36.5-178-175.4-78.3000112.4P436 L440 M520 A521 T528P436-H524 HydrophobicContact CG-CB 3.7Å; L440-H524 HydrophobicContact CD1-CB 3.85Å; L440-H524 VanDerWaalsContact CD1-ND1 3.28Å; L440-H524 WeakPolarHBondContact CD1-ND1 3.39Å; M520-H524 WeakPolarHBondContact O-CB 3.45Å; M520-H524 PolarHBondContact O-N 3.27Å; A521-H524 PolarHBondContact O-N 3.4Å; H524-T528 WeakPolarHBondContact O-CB 3.36Å; H524-T528 PolarHBondContact O-N 2.96Å; H524-T528 PolarHBondContact O-OG1 2.81Å
525Y97Very high93.1Very high11 Ų1147.3 Ų47.34%0.04321%0.211CC..Hα-helixtrans-61.4-47.5173.8178.2-102.4000111.8E444 I480 I483 A521 V522 Q523 T528 L529E444-Y525 WeakPolarHBondContact OE1-CE2 3.37Å; I480-Y525 HydrophobicContact CB-CE1 4.48Å; I480-Y525 HydrophobicContact CD1-CD2 4.1Å; I480-Y525 HydrophobicContact CD1-CG 4.01Å; I480-Y525 HydrophobicContact CG1-CD1 3.97Å; I480-Y525 HydrophobicContact CG1-CD2 4.35Å; I480-Y525 HydrophobicContact CG1-CE1 4.38Å; I480-Y525 HydrophobicContact CG1-CG 3.94Å; I480-Y525 HydrophobicContact CG2-CD1 4.3Å; I480-Y525 HydrophobicContact CG2-CD2 4.25Å; I480-Y525 HydrophobicContact CG2-CE1 3.88Å; I480-Y525 HydrophobicContact CG2-CE2 3.86Å; I480-Y525 HydrophobicContact CG2-CG 4.46Å; I483-Y525 HydrophobicContact CB-CE1 4.14Å; I483-Y525 HydrophobicContact CD1-CD1 4.37Å; I483-Y525 HydrophobicContact CG2-CD1 4.32Å; I483-Y525 HydrophobicContact CG2-CE1 3.82Å; A521-Y525 WeakPolarHBondContact O-CB 3.15Å; A521-Y525 PolarHBondContact O-N 2.81Å; V522-Y525 PolarHBondContact O-N 3.08Å; Q523-Y525 VanDerWaalsContact C-N 3.28Å; Q523-Y525 PolarHBondContact O-N 2.87Å; Y525-T528 PolarHBondContact O-N 3.48Å; Y525-L529 HydrophobicContact CE1-CD2 4.22Å; Y525-L529 WeakPolarHBondContact O-CB 3.46Å; Y525-L529 PolarHBondContact O-N 2.91Å
526I92.8Very high92.5Very high3 Ų352.7 Ų52.72%0.01524%0.236CC..Hα-helixtrans-65.2-44.4-179.8-69.3179.4000111.3A223 I226 I483 V488 V522 Q523 T528 L529 Q530A223-I526 HydrophobicContact CB-CD1 3.64Å; A223-I526 WeakPolarHBondContact O-CD1 3.32Å; I226-I526 HydrophobicContact CB-CD1 4.41Å; I226-I526 HydrophobicContact CG2-CB 4.36Å; I226-I526 HydrophobicContact CG2-CD1 3.87Å; I226-I526 HydrophobicContact CG2-CG2 4.48Å; I483-I526 HydrophobicContact CD1-CD1 3.74Å; I483-I526 HydrophobicContact CD1-CG1 3.95Å; I483-I526 HydrophobicContact CG1-CD1 4.47Å; I483-I526 HydrophobicContact CG2-CG1 4.36Å; V488-I526 HydrophobicContact CG1-CG2 4.33Å; V522-I526 HydrophobicContact CG1-CD1 4Å; V522-I526 WeakPolarHBondContact O-CG1 3.14Å; V522-I526 PolarHBondContact O-N 3.36Å; Q523-I526 PolarHBondContact O-N 2.78Å; Q523-I526 VanDerWaalsContact O-N 3.13Å; I526-T528 VanDerWaalsContact C-N 3.3Å; I526-T528 PolarHBondContact O-N 3.42Å; I526-L529 PolarHBondContact O-N 2.78Å; I526-Q530 HydrophobicContact CG2-CG 4.28Å; I526-Q530 WeakPolarHBondContact O-CB 3.37Å; I526-Q530 WeakPolarHBondContact O-CG 3.44Å; I526-Q530 PolarHBondContact O-N 3.5Å
527E93.2Very high91.9Very high71 Ų7152.8 Ų52.833%0.33224%0.24SC..Hα-helixtrans-57.5-44.2175.4-72.5172.9-174.200111.4Q523 Q530 R531Q523-E527 HydrophobicContact CG-CG 4.47Å; Q523-E527 VanDerWaalsContact CG-OE1 3.31Å; Q523-E527 WeakPolarHBondContact CG-OE1 3.33Å; Q523-E527 PolarHBondContact NE2-OE1 2.84Å; Q523-E527 WeakPolarHBondContact O-CG 3.43Å; Q523-E527 PolarHBondContact O-N 2.71Å; E527-Q530 PolarHBondContact O-N 3.01Å; E527-R531 WeakPolarHBondContact O-CB 3.34Å; E527-R531 PolarHBondContact O-N 3.38Å
528T92.4Very high91.2Very high24 Ų2458.2 Ų58.215%0.14726%0.264CS..Hα-helixtrans-68.6-35.7178.6-590000112.1H524 Y525 I526 R532H524-T528 WeakPolarHBondContact O-CB 3.36Å; H524-T528 PolarHBondContact O-N 2.96Å; H524-T528 PolarHBondContact O-OG1 2.81Å; Y525-T528 PolarHBondContact O-N 3.48Å; I526-T528 VanDerWaalsContact C-N 3.3Å; I526-T528 PolarHBondContact O-N 3.42Å; T528-R532 WeakPolarHBondContact O-CG 3.41Å; T528-R532 PolarHBondContact O-N 3.18Å; T528-R532 PolarHBondContact O-NE 3Å
529L88.9Confident90.4Very high36 Ų3662.2 Ų62.219%0.18829%0.292CS..Hα-helixtrans-68.7-46.3175.6-179.660.1000111.5I483 V488 Y525 I526 R531 R532 I533I483-L529 HydrophobicContact CG2-CD2 3.98Å; V488-L529 HydrophobicContact CG1-CD2 3.89Å; V488-L529 HydrophobicContact CG1-CG 4.46Å; Y525-L529 HydrophobicContact CE1-CD2 4.22Å; Y525-L529 WeakPolarHBondContact O-CB 3.46Å; Y525-L529 PolarHBondContact O-N 2.91Å; I526-L529 PolarHBondContact O-N 2.78Å; L529-R531 PolarHBondContact O-N 3.23Å; L529-R532 PolarHBondContact O-N 3Å; L529-I533 HydrophobicContact CD1-CD1 4.26Å; L529-I533 HydrophobicContact CG-CD1 4.04Å; L529-I533 WeakPolarHBondContact O-CG1 3.2Å; L529-I533 PolarHBondContact O-N 3.19Å
530Q86.4Confident89.3Confident69 Ų6968.6 Ų68.632%0.32232%0.32SS..Hα-helixtrans-59.4-46.2176.8-74.8174.3-21.300111.3V488 I526 E527 R532 I533 E534V488-Q530 HydrophobicContact CG1-CG 4.34Å; I526-Q530 HydrophobicContact CG2-CG 4.28Å; I526-Q530 WeakPolarHBondContact O-CB 3.37Å; I526-Q530 WeakPolarHBondContact O-CG 3.44Å; I526-Q530 PolarHBondContact O-N 3.5Å; E527-Q530 PolarHBondContact O-N 3.01Å; Q530-R532 VanDerWaalsContact C-N 3.34Å; Q530-R532 PolarHBondContact O-N 3.01Å; Q530-I533 PolarHBondContact O-N 3.39Å; Q530-E534 WeakPolarHBondContact O-CG 3.32Å; Q530-E534 PolarHBondContact O-N 2.99Å
531R89.1Confident88.2Confident133 Ų13373.8 Ų73.850%0.50234%0.336SS..Hα-helixtrans-57.5-44.4175.6-175.6174.762.2-134.4-3.9112.2E527 L529 E534 E535E527-R531 WeakPolarHBondContact O-CB 3.34Å; E527-R531 PolarHBondContact O-N 3.38Å; L529-R531 PolarHBondContact O-N 3.23Å; R531-E534 PolarHBondContact O-N 3.47Å; R531-E535 WeakPolarHBondContact O-CG 3.45Å; R531-E535 PolarHBondContact O-N 2.92Å
532R87.6Confident86.6Confident109 Ų10980.8 Ų80.841%0.41137%0.366SS..Hα-helixtrans-60.4-45.3175.8-79.1-174.6-84.1-169.4-2.6111.9T528 L529 Q530 E534 E535 E536T528-R532 WeakPolarHBondContact O-CG 3.41Å; T528-R532 PolarHBondContact O-N 3.18Å; T528-R532 PolarHBondContact O-NE 3Å; L529-R532 PolarHBondContact O-N 3Å; Q530-R532 VanDerWaalsContact C-N 3.34Å; Q530-R532 PolarHBondContact O-N 3.01Å; R532-E534 PolarHBondContact O-N 3.48Å; R532-E535 PolarHBondContact O-N 3.35Å; R532-E536 WeakPolarHBondContact O-CG 3.35Å; R532-E536 PolarHBondContact O-N 3.35Å
533I83.6Confident84.6Confident69 Ų6983.5 Ų83.535%0.35439%0.394SS..Hα-helixtrans-61.5-44.4177.7-67.3165.9000111.1L529 Q530 E536 Q537L529-I533 HydrophobicContact CD1-CD1 4.26Å; L529-I533 HydrophobicContact CG-CD1 4.04Å; L529-I533 WeakPolarHBondContact O-CG1 3.2Å; L529-I533 PolarHBondContact O-N 3.19Å; Q530-I533 PolarHBondContact O-N 3.39Å; I533-E536 PolarHBondContact O-N 2.99Å; I533-Q537 WeakPolarHBondContact O-CG 3.45Å; I533-Q537 PolarHBondContact O-N 3.44Å
534E85.7Confident82.6Confident105 Ų10589.1 Ų89.149%0.49142%0.42SS..Hα-helixtrans-63.1-42177.8-73.5-177.2-16800112.8Q530 R531 R532 Q537 K538Q530-E534 WeakPolarHBondContact O-CG 3.32Å; Q530-E534 PolarHBondContact O-N 2.99Å; R531-E534 PolarHBondContact O-N 3.47Å; R532-E534 PolarHBondContact O-N 3.48Å; E534-Q537 PolarHBondContact O-N 2.89Å; E534-K538 WeakPolarHBondContact O-CB 3.37Å; E534-K538 VanDerWaalsContact O-CG 3.29Å; E534-K538 WeakPolarHBondContact O-CG 3.35Å; E534-K538 PolarHBondContact O-N 3.37Å; E534-K538 IonicContact OE2-NZ 3.77Å
535E86.4Confident80.2Confident110 Ų11093.4 Ų93.451%0.51444%0.441SS..Hα-helixtrans-64.4-43.2177.6-75172.9-177.200111.6R531 R532 Q537 K538 S539R531-E535 WeakPolarHBondContact O-CG 3.45Å; R531-E535 PolarHBondContact O-N 2.92Å; R532-E535 PolarHBondContact O-N 3.35Å; E535-Q537 PolarHBondContact O-N 3.42Å; E535-K538 PolarHBondContact O-N 3.29Å; E535-S539 WeakPolarHBondContact O-CB 3.35Å; E535-S539 PolarHBondContact O-N 3.48Å
536E84.6Confident77.9Confident114 Ų114102.2 Ų102.253%0.53348%0.475SS..Hα-helixtrans-61.7-41.8173.8-75.2-176.7-170.200112.2R532 I533 S539 K540R532-E536 WeakPolarHBondContact O-CG 3.35Å; R532-E536 PolarHBondContact O-N 3.35Å; I533-E536 PolarHBondContact O-N 2.99Å; E536-S539 PolarHBondContact O-N 2.93Å; E536-K540 WeakPolarHBondContact O-CG 3.29Å; E536-K540 PolarHBondContact O-N 3.37Å
537Q82.6Confident75.7Confident99 Ų99107.5 Ų107.546%0.46351%0.508SS..Hα-helixtrans-64.9-42175.6-73.6-169.310.400112I533 E534 E535 S539 K540 R541I533-Q537 WeakPolarHBondContact O-CG 3.45Å; I533-Q537 PolarHBondContact O-N 3.44Å; E534-Q537 PolarHBondContact O-N 2.89Å; E535-Q537 PolarHBondContact O-N 3.42Å; Q537-S539 VanDerWaalsContact C-N 3.34Å; Q537-K540 PolarHBondContact O-N 3Å; Q537-R541 WeakPolarHBondContact O-CG 3.44Å; Q537-R541 PolarHBondContact O-N 2.87Å
538K83.6Confident73.3Confident122 Ų122110.8 Ų110.853%0.5353%0.528SS..Hα-helixtrans-61.8-41.8174.6-75.5167.9-175.4161.20111.2E534 E535 R541 K542E534-K538 WeakPolarHBondContact O-CB 3.37Å; E534-K538 VanDerWaalsContact O-CG 3.29Å; E534-K538 WeakPolarHBondContact O-CG 3.35Å; E534-K538 PolarHBondContact O-N 3.37Å; E534-K538 IonicContact OE2-NZ 3.77Å; E535-K538 PolarHBondContact O-N 3.29Å; K538-R541 PolarHBondContact O-N 3Å; K538-K542 PolarHBondContact O-N 3.19Å; K538-K542 VanDerWaalsContact O-N 3.09Å
539S80.8Confident71Confident85 Ų85115.5 Ų115.559%0.59455%0.551SS**Hα-helixtrans-65.2-43.6177.4-169.50000112.1E535 E536 Q537 K542 G543E535-S539 WeakPolarHBondContact O-CB 3.35Å; E535-S539 PolarHBondContact O-N 3.48Å; E536-S539 PolarHBondContact O-N 2.93Å; Q537-S539 VanDerWaalsContact C-N 3.34Å; S539-K542 PolarHBondContact O-N 3.37Å; S539-G543 PolarHBondContact O-N 3.04Å
540K75.3Confident68.6Low135 Ų135123 Ų12359%0.58758%0.582SS**Hα-helixtrans-61.4-44175.3-73.9171.5-177.9167.80111.6E536 Q537 K542 G543 H544E536-K540 WeakPolarHBondContact O-CG 3.29Å; E536-K540 PolarHBondContact O-N 3.37Å; Q537-K540 PolarHBondContact O-N 3Å; K540-K542 PolarHBondContact O-N 3.09Å; K540-G543 PolarHBondContact O-N 3.23Å; K540-H544 PolarHBondContact O-CD2 3.44Å; K540-H544 PolarHBondContact O-N 3.48Å
541R73.6Confident66.2Low172 Ų172129.8 Ų129.865%0.64961%0.606SS**Hα-helixtrans-60.8-43.6176.8-72.5177.4-170.6-175.96.2112.5Q537 K538 G543 H544 E545Q537-R541 WeakPolarHBondContact O-CG 3.44Å; Q537-R541 PolarHBondContact O-N 2.87Å; K538-R541 PolarHBondContact O-N 3Å; R541-G543 VanDerWaalsContact C-N 3.33Å; R541-G543 PolarHBondContact O-N 3.21Å; R541-H544 PolarHBondContact O-N 3.34Å; R541-E545 PolarHBondContact O-N 3.46Å
542K64.4Low63.6Low146 Ų146128.9 Ų128.964%0.63562%0.62SS**Hα-helixtrans-65.4-33.2174.8-72.6-176.5177.5-175.30113.1K538 S539 K540 H544 E545K538-K542 PolarHBondContact O-N 3.19Å; K538-K542 VanDerWaalsContact O-N 3.09Å; S539-K542 PolarHBondContact O-N 3.37Å; K540-K542 PolarHBondContact O-N 3.09Å; K542-H544 VanDerWaalsContact C-N 3.29Å; K542-H544 PolarHBondContact O-N 3.48Å; K542-E545 PolarHBondContact O-N 3.43Å
543G56Low61.5Low57 Ų57132.1 Ų132.159%0.58864%0.644SS**Hα-helixtrans-67.3-25.5174.400000114.2S539 K540 R541S539-G543 PolarHBondContact O-N 3.04Å; K540-G543 PolarHBondContact O-N 3.23Å; R541-G543 VanDerWaalsContact C-N 3.33Å; R541-G543 PolarHBondContact O-N 3.21Å
544H54.1Low59.2Low143 Ų143132.8 Ų132.866%0.66266%0.66SS**THydrogen-bonded Turntrans-86.3-9175.8-72.3-70.1000114.1K540 R541 K542 Y546K540-H544 PolarHBondContact O-CD2 3.44Å; K540-H544 PolarHBondContact O-N 3.48Å; R541-H544 PolarHBondContact O-N 3.34Å; K542-H544 VanDerWaalsContact C-N 3.29Å; K542-H544 PolarHBondContact O-N 3.48Å; H544-Y546 VanDerWaalsContact C-N 3.3Å; H544-Y546 PolarHBondContact O-N 3.39Å
545E46.5Very low56.7Low149 Ų149135.9 Ų135.970%0.69668%0.68SS**SBendtrans-80.2-2.2-178.5-79.8179.4159.200114.4R541 K542R541-E545 PolarHBondContact O-N 3.46Å; K542-E545 PolarHBondContact O-N 3.43Å
546Y48.1Very low54.2Low195 Ų195139.3 Ų139.377%0.76570%0.696SS**  trans-101.940.6176.6-68.8-79.6000114.6H544H544-Y546 VanDerWaalsContact C-N 3.3Å; H544-Y546 PolarHBondContact O-N 3.39Å
547T47.2Very low51.7Low115 Ų115140.1 Ų140.171%0.70671%0.709SS**  trans-96.28.6172.357.10000114.4
548N42.6Very low49.3Very low139 Ų139141.4 Ų141.474%0.74373%0.729SS**  trans-118.825.1-168.6-62.2-12.9000115.5K550N548-K550 VanDerWaalsContact C-N 3.34Å; N548-K550 PolarHBondContact O-N 3.19Å
549I42.9Very low46.8Very low123 Ų123139.2 Ų139.263%0.63174%0.741SS**  trans-8684.3163.3-53.5-179.8000108Y551I549-Y551 HydrophobicContact CG2-CD2 4Å; I549-Y551 HydrophobicContact CG2-CE2 3.83Å; I549-Y551 PolarHBondContact O-N 3.27Å
550K39Very low44.4Very low195 Ų195142.1 Ų142.185%0.84875%0.75SS**  trans-69.2107.7157.2-79.7-177.1177179.20106.8N548 S552N548-K550 VanDerWaalsContact C-N 3.34Å; N548-K550 PolarHBondContact O-N 3.19Å; K550-S552 PolarHBondContact O-N 3.29Å
551Y36.3Very low42.2Very low211 Ų211143.8 Ų143.883%0.82776%0.76SS**  trans-65.3107.4158.3-79.4-84.3000107.4I549 L553I549-Y551 HydrophobicContact CG2-CD2 4Å; I549-Y551 HydrophobicContact CG2-CE2 3.83Å; I549-Y551 PolarHBondContact O-N 3.27Å; Y551-L553 PolarHBondContact O-N 3.07Å
552S34.6Very low40.3Very low113 Ų113140.9 Ų140.979%0.7977%0.765SS**  trans-66114.8172.4380000109.5K550 A554K550-S552 PolarHBondContact O-N 3.29Å; S552-A554 PolarHBondContact O-N 3.12Å; S552-A554 VanDerWaalsContact O-N 3.12Å
553L42.8Very low39Very low177 Ų177139.5 Ų139.593%0.92777%0.772SS**  trans-65.796.6162.4-82.1153.8000109.1Y551Y551-L553 PolarHBondContact O-N 3.07Å
554A35.8Very low38Very low83 Ų83144.5 Ų144.569%0.68678%0.784SS**  trans-172.487.3154.400000109.1S552S552-A554 PolarHBondContact O-N 3.12Å; S552-A554 VanDerWaalsContact O-N 3.12Å
555D33.5Very low37.3Very low170 Ų170143.3 Ų143.391%0.90979%0.789SS**  trans-168.588.3136.6-96.5-16000107.1
556Q34.3Very low37Very low183 Ų183141.4 Ų141.486%0.85579%0.789SS**  trans-105.3110158.8-80.2-173.58.200107.3
557T32.3Very low36Very low131 Ų131137.2 Ų137.280%0.80479%0.788SS**  trans-151.7119.9134.833.90000111.3
558S32.2Very low35.1Very low126 Ų126138 Ų13888%0.88179%0.792SS**  trans66.2119.2150.558.60000121.2
559G29.7Very low34.7Very low75 Ų75136.8 Ų136.877%0.77379%0.792SS**  trans144.781.6142.400000117.1
560D30.8Very low34.2Very low146 Ų146137.1 Ų137.178%0.78180%0.8SS**  trans62.6109.8151.9-74.9-23.9000123.9
561Q30.5Very low34Very low171 Ų171133.5 Ų133.580%0.79980%0.796SS**  36.9115.3121.3-62.8-170.710.200117.3
562S32.1Very low34.2Very low110 Ų110129 Ų12977%0.76979%0.793SS**  174.7169.566.7-98.90000110.9
563P38.8Very low33.9Very low118 Ų118129.9 Ų129.977%0.76680%0.798SS**  trans-104.5159.2-141.138.9-34.7000117
564L34.9Very low33.2Very low161 Ų161125.8 Ų125.884%0.84379%0.79SS**  trans-46.5160.4155.6-70.5164.2000111.5
565P37.6Very low32.8Very low118 Ų118130.5 Ų130.577%0.76680%0.797SS**  -159.2-156.870.451-27.7000114
566P41.6Very low32.6Very low109 Ų109129.7 Ų129.771%0.70879%0.79SS**  -133.4-174.6-117.831.2-3.9000115.2
567C26.7Very low32.3Very low108 Ų108130.8 Ų130.873%0.7379%0.786SS**  trans66116.6150.5-70.80000122.4
568T27.5Very low32.2Very low130 Ų130132.2 Ų132.280%0.79878%0.784SS**  trans56.8165.8137.156.30000119.6
569P35.2Very low32Very low114 Ų114133 Ų13374%0.7478%0.778SS**  cis-127.7-179.3-1924.60.1000113.5
570T32.7Very low32Very low131 Ų131134.2 Ų134.280%0.80478%0.775SS**  trans-35.7150.1165.537.90000115.6
571P34.1Very low31.9Very low118 Ų118131.4 Ų131.477%0.76677%0.772SS**  -158.4-148.772.839.7-15.2000113.6
572P40.5Very low31.9Very low116 Ų116134.6 Ų134.675%0.75378%0.776SS**  -123177.5-57.128.2-7.5000114.2
573C28.5Very low31.9Very low132 Ų132135.3 Ų135.389%0.89278%0.776SS**  trans7133.1153.1-94.10000122
574A28Very low31.5Very low92 Ų92140 Ų14076%0.7678%0.78SS**  168.1111.9127.800000109.3
575E28.3Very low31.3Very low181 Ų181140.3 Ų140.385%0.84678%0.777SS**  70113.399.9-80.3-165.3166.300117
576M28Very low30.9Very low153 Ų153142.6 Ų142.675%0.75478%0.783SS**  trans53.7118134.3-60.6-157.575.900121.7
577R28.5Very low30.5Very low207 Ų207143 Ų14378%0.78178%0.783SS**  153.7122.4114.1-87.3-174.7177.6-179.6-1.8109.8
578E29.1Very low30.7Very low161 Ų161141 Ų14175%0.75278%0.781SS**  48.1119.4104.2-73.7177.2160.900111.4
579D29.2Very low30.9Very low143 Ų143142.1 Ų142.177%0.76578%0.781SS**  -172.4165.560.2-137.1-23.2000113.1
580S29.3Very low30.7Very low100 Ų100144.2 Ų144.270%0.69978%0.782SS**  trans85.2104.6145.266.80000122.7
581A29Very low30.6Very low87 Ų87147.3 Ų147.372%0.71979%0.788SS**  85.5117115.600000121
582R31.4Very low30.7Very low237 Ų237150 Ų15089%0.89479%0.79SS**  163109.8113.3-85.4167.9-173.4-163.92.5108.9
583V31.6Very low30.3Very low125 Ų125152.9 Ų152.976%0.75879%0.794SS**  78.3108.785.11680000112.7
584Y29.8Very low30.6Very low217 Ų217155.7 Ų155.785%0.85179%0.791SS**  trans76.2116.4151.7-80.7-101.1000122.3
585E31.8Very low30.9Very low168 Ų168155.7 Ų155.779%0.78579%0.785SS**  trans-60.9149.3152.2-65.7173.1134.400111.7
586N29.2Very low31.2Very low165 Ų165156.5 Ų156.588%0.88279%0.786SS**  -155.8151.4123.6-114.5-30.8000113.8
587V32.8Very low31.8Very low119 Ų119164.5 Ų164.572%0.72181%0.808SS**  trans-98.7153.9-161.8173.30000111.7
588G29.7Very low32Very low65 Ų65162.4 Ų162.467%0.6781%0.81SS**  trans99.4149.4137.900000116
589L32.1Very low32.2Very low153 Ų153162.5 Ų162.580%0.80181%0.813SS**  cis-174.1149.1-0.2-121.1160.1000106.3
590M31.7Very low32.3Very low158 Ų158163.6 Ų163.678%0.77882%0.815SS**  trans1.2138159.7-68.4173.291.100121
591Q31Very low32.5Very low196 Ų196167.3 Ų167.392%0.91682%0.822SS**  -164.1138.3113.4-113.7174.415.900114.1
592Q35.7Very low32.7Very low174 Ų174172.3 Ų172.381%0.81383%0.828SS**  trans-76.6148.9167-68.7174.5-20.600111.2
593Q31.8Very low32.8Very low178 Ų178168 Ų16883%0.83282%0.824SS**  -170.8122124.5-106.5-178.817.200114.3
594K35.3Very low32.9Very low190 Ų190171.1 Ų171.183%0.82683%0.829SS**  trans52122.6133.9-72.8-177.6176.1-179.90123.4
595S33.3Very low33.2Very low92 Ų92167.5 Ų167.564%0.64383%0.827SS**  75.3119.7125.2-162.70000119.6
596F34.5Very low33.3Very low199 Ų199167.5 Ų167.587%0.87383%0.831SS**  -177.9137104.8-103.6-77.9000111.5
597R42.3Very low33.6Very low321 Ų321167.7 Ų167.7100%1.21183%0.826SS**  trans82.30173.6-68.3-170.5178.1-174.80.4118.5

Retrieved 597 of 597 residues in 2987.1 ms (Link to these results)