A0A096N3M5_PAPAN Loading...

Phosphoglycerate mutase

AlphaFold DB (A0A7N9D5V5), UniProt , Accession A0A096N3M5, Species PAPAN (Papio anubis, Olive baboon), Gene PGAM2, Length 253 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M55.9Low89.3Confident221 Ų22145.2 Ų45.2100%1.08923%0.234SC*.  0146.10-65.7-179.3-16700107.5T3M1-T3 PolarHBondContact O-N 2.93Å; M1-T3 PolarHBondContact O-OG1 3.33Å
2A60.2Low89.9Confident55 Ų5541.4 Ų41.446%0.45522%0.215SC..  trans-64121.2177.200000109
3T84.8Confident90.4Very high72 Ų7240.8 Ų40.844%0.44221%0.21SC..  trans-111.1122.3179.8-55.80000107.8M1 E219 L220M1-T3 PolarHBondContact O-N 2.93Å; M1-T3 PolarHBondContact O-OG1 3.33Å; T3-E219 HydrophobicContact CG2-CB 3.58Å; T3-E219 HydrophobicContact CG2-CG 3.83Å; T3-L220 CarbonylContact C-O 3.53Å; T3-L220 WeakPolarHBondContact CA-O 3.35Å
4H95.6Very high90.8Very high29 Ų2937.9 Ų37.913%0.13420%0.195CC..EExtended strand (participates in β ladder)trans-86.4146172.8-56-77.9000109.7I175 E219 L220H4-I175 HydrophobicContact CB-CG2 3.53Å; H4-I175 PolarHBondContact CE1-O 3.03Å; H4-I175 PolarHBondContact ND1-O 3.2Å; H4-E219 WeakPolarHBondContact O-CA 3.35Å; H4-L220 HydrophobicContact CB-CB 4.36Å; H4-L220 PolarHBondContact N-O 3.35Å; H4-L220 PolarHBondContact O-N 2.82Å
5R95.4Very high91.2Very high83 Ų8338.2 Ų38.231%0.31320%0.2SC..EExtended strand (participates in β ladder)trans-114127175.9-169.9171.864-162.81.3110.5V217 Y218R5-V217 HydrophobicContact CG-CG1 3.92Å; R5-Y218 WeakPolarHBondContact CA-O 3.32Å
6L98Very high91.5Very high0 Ų036.9 Ų36.90%019%0.191CC..EExtended strand (participates in β ladder)trans-118.3135.5174.5168.869.1000108.7M8 W167 I175 V181 I183 L197 Y218 L220L6-M8 HydrophobicContact CD1-CG 4.29Å; L6-M8 HydrophobicContact CD2-CE 4.42Å; L6-M8 HydrophobicContact CD2-CG 4.05Å; L6-M8 HydrophobicContact CD2-SD 4.09Å; L6-M8 HydrophobicContact CG-CG 4.01Å; L6-W167 HydrophobicContact CD2-CH2 3.7Å; L6-W167 HydrophobicContact CD2-CZ3 3.85Å; L6-I175 HydrophobicContact CD1-CD1 4.45Å; L6-V181 HydrophobicContact CD1-CB 3.87Å; L6-V181 HydrophobicContact CD1-CG1 3.86Å; L6-I183 HydrophobicContact CD1-CD1 3.82Å; L6-I183 HydrophobicContact CD1-CG1 4Å; L6-L197 HydrophobicContact CD2-CD1 4.13Å; L6-Y218 PolarHBondContact N-O 3.25Å; L6-Y218 PolarHBondContact O-N 3.46Å; L6-L220 HydrophobicContact CB-CD1 4.3Å; L6-L220 HydrophobicContact CD2-CD1 4.5Å
7V98.7Very high91.3Very high1 Ų137.3 Ų37.31%0.00619%0.194CC..EExtended strand (participates in β ladder)trans-115.6130.6170.3-178.30000109.6V9 I45 M50 F52 V181 L182 I183 P215 I216 V217V7-V9 HydrophobicContact CG1-CG2 4.33Å; V7-I45 HydrophobicContact CG1-CD1 4.48Å; V7-M50 HydrophobicContact CG2-SD 3.84Å; V7-F52 HydrophobicContact CB-CE1 3.73Å; V7-F52 HydrophobicContact CB-CZ 4.04Å; V7-F52 HydrophobicContact CG1-CZ 4.34Å; V7-F52 HydrophobicContact CG2-CE1 3.58Å; V7-F52 HydrophobicContact CG2-CZ 3.96Å; V7-V181 PolarHBondContact N-O 2.98Å; V7-L182 HydrophobicContact CB-CD1 3.97Å; V7-L182 HydrophobicContact CG1-CD1 3.72Å; V7-L182 CarbonylContact O-C 3.55Å; V7-L182 WeakPolarHBondContact O-CA 3.32Å; V7-I183 PolarHBondContact O-N 3.17Å; V7-P215 HydrophobicContact CG1-CB 3.93Å; V7-I216 CarbonylContact C-O 3.53Å; V7-I216 VanDerWaalsContact CA-O 3.32Å; V7-I216 WeakPolarHBondContact CA-O 3.46Å; V7-V217 HydrophobicContact CG2-CG2 4.23Å
8M98.7Very high91.2Very high0 Ų041.1 Ų41.10%021%0.21CC..EExtended strand (participates in β ladder)trans-122.8140174.5-59.4-168.9-71.600110L6 I183 L190 I193 V194 L197 I216 Y218L6-M8 HydrophobicContact CD1-CG 4.29Å; L6-M8 HydrophobicContact CD2-CE 4.42Å; L6-M8 HydrophobicContact CD2-CG 4.05Å; L6-M8 HydrophobicContact CD2-SD 4.09Å; L6-M8 HydrophobicContact CG-CG 4.01Å; M8-I183 CarbonylContact C-O 3.59Å; M8-I183 VanDerWaalsContact CA-O 3.29Å; M8-I183 WeakPolarHBondContact CA-O 3.15Å; M8-I183 HydrophobicContact CG-CB 4.15Å; M8-I183 HydrophobicContact CG-CD1 4.19Å; M8-I183 HydrophobicContact CG-CG1 4.44Å; M8-I183 HydrophobicContact SD-CD1 4.32Å; M8-L190 HydrophobicContact CB-CD1 4.42Å; M8-L190 HydrophobicContact CB-CD2 4.05Å; M8-L190 HydrophobicContact CG-CD2 4.3Å; M8-L190 HydrophobicContact SD-CD2 3.84Å; M8-I193 HydrophobicContact CE-CG2 4.38Å; M8-I193 HydrophobicContact SD-CB 4.25Å; M8-I193 HydrophobicContact SD-CD1 4.43Å; M8-I193 HydrophobicContact SD-CG2 3.79Å; M8-V194 HydrophobicContact CE-CG2 3.81Å; M8-L197 HydrophobicContact CE-CD1 4.37Å; M8-I216 PolarHBondContact N-O 2.9Å; M8-I216 WeakPolarHBondContact O-CA 3.35Å; M8-I216 WeakPolarHBondContact O-CB 3.46Å; M8-I216 PolarHBondContact O-N 3.48Å; M8-Y218 HydrophobicContact CE-CD2 3.65Å; M8-Y218 HydrophobicContact CE-CE2 3.36Å
9V98.6Very high91.2Very high0 Ų043.7 Ų43.70%022%0.222CC..EExtended strand (participates in β ladder)trans-134.5122.8179.4-176.90000108.4V7 T66 I70 L182 I183 A184 A185 P215V7-V9 HydrophobicContact CG1-CG2 4.33Å; V9-T66 HydrophobicContact CG1-CG2 4.06Å; V9-I70 HydrophobicContact CB-CD1 4.25Å; V9-I70 HydrophobicContact CG1-CD1 4.19Å; V9-I70 HydrophobicContact CG2-CD1 3.88Å; V9-L182 HydrophobicContact CG2-CD1 4.14Å; V9-I183 PolarHBondContact N-O 3.39Å; V9-A184 WeakPolarHBondContact O-CA 3.45Å; V9-A185 PolarHBondContact O-N 3.49Å; V9-P215 HydrophobicContact CG2-CB 3.82Å; V9-P215 HydrophobicContact CG2-CG 4.13Å
10R98.2Very high91.1Very high32 Ų3244.8 Ų44.812%0.12123%0.228CC..EExtended strand (participates in β ladder)trans-73132.3163.5177.4-174.6172.3-172.4-5.8107.5A185 L190 L210 P211 T212 G213R10-A185 WeakPolarHBondContact CA-O 3.42Å; R10-L190 HydrophobicContact CB-CD1 4.12Å; R10-L210 WeakPolarHBondContact CD-O 3.41Å; R10-L210 PolarHBondContact NH1-O 3.16Å; R10-P211 WeakPolarHBondContact CB-O 3.34Å; R10-T212 HydrophobicContact CG-CG2 4.41Å; R10-T212 VanDerWaalsContact CZ-CG2 3.45Å; R10-G213 WeakPolarHBondContact O-CA 3.43Å; R10-G213 PolarHBondContact O-N 3.01Å
11H98.4Very high91.2Very high4 Ų446.7 Ų46.72%0.01923%0.232CC..PPolyproline II helixtrans-51.1154176.67080.1000113.1L30 R62 T66 A185 H186 T212H11-L30 HydrophobicContact CB-CD2 4.44Å; H11-R62 WeakPolarHBondContact CE1-CD 3.39Å; H11-R62 PolarHBondContact NE2-NE 3.29Å; H11-T66 WeakPolarHBondContact CA-OG1 3.37Å; H11-T66 VanDerWaalsContact CB-OG1 3.31Å; H11-T66 WeakPolarHBondContact CB-OG1 3.38Å; H11-A185 PolarHBondContact CD2-O 2.97Å; H11-A185 PolarHBondContact N-O 3.41Å; H11-H186 AromaticContact CD2-CE1 3.6Å; H11-H186 AromaticContact CD2-CG 3.82Å; H11-H186 AromaticContact CD2-ND1 2.99Å; H11-H186 PolarHBondContact CD2-ND1 3.47Å; H11-H186 AromaticContact NE2-CE1 3.82Å; H11-H186 AromaticContact NE2-CG 3.99Å; H11-H186 AromaticContact NE2-ND1 3Å; H11-H186 PolarHBondContact NE2-ND1 3.16Å; H11-T212 WeakPolarHBondContact O-CB 3.2Å; H11-T212 WeakPolarHBondContact O-CG2 3.32Å
12G96.4Very high93Very high0 Ų036.1 Ų36.10%018%0.18CC..PPolyproline II helixtrans-61.6167.8173.100000112.7S14 L30 E37 T66G12-S14 PolarHBondContact O-N 2.99Å; G12-L30 VanDerWaalsContact O-CD2 3.29Å; G12-L30 WeakPolarHBondContact O-CD2 3.34Å; G12-E37 WeakPolarHBondContact CA-OE2 3.48Å; G12-T66 PolarHBondContact N-OG1 3.3Å
13E96.1Very high94.7Very high33 Ų3333.9 Ų33.915%0.15416%0.161CC..PPolyproline II helixtrans-47.7130.4176.9-168.1-176.5-100.100112.7N17 Q18 S31 K33 G34 E37E13-N17 HydrophobicContact CG-CB 3.82Å; E13-Q18 VanDerWaalsContact CD-CG 3.43Å; E13-Q18 HydrophobicContact CG-CG 3.88Å; E13-Q18 VanDerWaalsContact OE2-CD 3.28Å; E13-Q18 WeakPolarHBondContact OE2-CG 3.46Å; E13-Q18 PolarHBondContact OE2-NE2 3.43Å; E13-S31 PolarHBondContact O-N 3.06Å; E13-S31 PolarHBondContact O-OG 2.81Å; E13-S31 PolarHBondContact OE2-OG 2.92Å; E13-K33 IonicContact OE1-NZ 3.26Å; E13-K33 PolarHBondContact OE1-NZ 3.26Å; E13-K33 WeakPolarHBondContact OE2-CD 3.31Å; E13-K33 IonicContact OE2-NZ 2.62Å; E13-G34 VanDerWaalsContact O-CA 3.32Å; E13-G34 WeakPolarHBondContact O-CA 3.48Å; E13-E37 PolarHBondContact N-OE2 3.43Å
14S97Very high95.2Very high0 Ų030.5 Ų30.50%014%0.141CC..BIsolated β-bridgetrans-91.9161171.963.90000111.6G12 W16 N17 Q18 E29G12-S14 PolarHBondContact O-N 2.99Å; S14-W16 PolarHBondContact O-N 3.29Å; S14-N17 PolarHBondContact N-OD1 3.38Å; S14-N17 WeakPolarHBondContact O-CA 3.27Å; S14-N17 WeakPolarHBondContact O-CB 3.23Å; S14-N17 PolarHBondContact O-N 3.44Å; S14-N17 PolarHBondContact OG-N 3.08Å; S14-N17 PolarHBondContact OG-OD1 3.34Å; S14-Q18 PolarHBondContact O-N 2.98Å; S14-Q18 VanDerWaalsContact O-N 3.15Å; S14-E29 VanDerWaalsContact CA-O 3.3Å; S14-E29 WeakPolarHBondContact CA-O 3.43Å; S14-E29 VanDerWaalsContact CB-O 3.29Å; S14-E29 WeakPolarHBondContact CB-O 3.5Å
15T96.9Very high95.4Very high43 Ų4329.2 Ų29.226%0.26413%0.134SC..Hα-helixtrans-48.6-43.8171.146.40000112.1N17 Q18 E19 E29T15-N17 VanDerWaalsContact C-N 3.35Å; T15-N17 PolarHBondContact O-N 3.05Å; T15-Q18 WeakPolarHBondContact O-CB 3.46Å; T15-Q18 PolarHBondContact O-N 3.49Å; T15-E19 PolarHBondContact O-N 3.21Å; T15-E19 VanDerWaalsContact O-N 3.16Å; T15-E29 PolarHBondContact N-O 3.29Å; T15-E29 PolarHBondContact OG1-O 3.04Å
16W95.2Very high95.5Very high18 Ų1827.5 Ų27.57%0.06813%0.13CC..Hα-helixtrans-75.3-18.4176.8-8024.3000114.8S14 N20 R21 F22 C23 F26 A28 T96 Y132S14-W16 PolarHBondContact O-N 3.29Å; W16-N20 PolarHBondContact O-N 3.24Å; W16-R21 HydrophobicContact CB-CB 4.21Å; W16-R21 HydrophobicContact CD2-CB 4.19Å; W16-R21 HydrophobicContact CE3-CB 4.01Å; W16-R21 HydrophobicContact CG-CB 4.28Å; W16-R21 PolarHBondContact O-N 2.87Å; W16-F22 WeakPolarHBondContact CZ3-O 3.44Å; W16-C23 HydrophobicContact CB-CB 4.11Å; W16-C23 HydrophobicContact CE3-CB 4.05Å; W16-F26 AromaticContact CD2-CD1 3.65Å; W16-F26 HydrophobicContact CD2-CD1 3.65Å; W16-F26 AromaticContact CD2-CE1 3.94Å; W16-F26 HydrophobicContact CD2-CE1 3.94Å; W16-F26 HydrophobicContact CD2-CG 4.5Å; W16-F26 AromaticContact CE2-CD1 3.41Å; W16-F26 VanDerWaalsContact CE2-CD1 3.41Å; W16-F26 AromaticContact CE2-CE1 3.29Å; W16-F26 HydrophobicContact CE3-CB 4.35Å; W16-F26 AromaticContact CE3-CD1 3.82Å; W16-F26 HydrophobicContact CE3-CD1 3.82Å; W16-F26 HydrophobicContact CE3-CG 4.3Å; W16-F26 HydrophobicContact CG-CD1 4.4Å; W16-F26 HydrophobicContact CG-CE1 4.5Å; W16-F26 HydrophobicContact CH2-CB 3.8Å; W16-F26 AromaticContact CH2-CD1 3.42Å; W16-F26 HydrophobicContact CH2-CD1 3.42Å; W16-F26 VanDerWaalsContact CH2-CD1 3.42Å; W16-F26 AromaticContact CH2-CD2 3.78Å; W16-F26 HydrophobicContact CH2-CD2 3.78Å; W16-F26 AromaticContact CH2-CE1 3.89Å; W16-F26 HydrophobicContact CH2-CE1 3.89Å; W16-F26 HydrophobicContact CH2-CE2 4.2Å; W16-F26 AromaticContact CH2-CG 3.36Å; W16-F26 HydrophobicContact CH2-CG 3.36Å; W16-F26 HydrophobicContact CH2-CZ 4.26Å; W16-F26 AromaticContact CZ2-CD1 3.32Å; W16-F26 HydrophobicContact CZ2-CD1 3.32Å; W16-F26 HydrophobicContact CZ2-CD2 4.01Å; W16-F26 AromaticContact CZ2-CE1 3.29Å; W16-F26 HydrophobicContact CZ2-CE1 3.29Å; W16-F26 AromaticContact CZ2-CE2 3.97Å; W16-F26 HydrophobicContact CZ2-CE2 3.97Å; W16-F26 AromaticContact CZ2-CG 3.7Å; W16-F26 HydrophobicContact CZ2-CG 3.7Å; W16-F26 AromaticContact CZ2-CZ 3.62Å; W16-F26 HydrophobicContact CZ2-CZ 3.62Å; W16-F26 HydrophobicContact CZ3-CB 3.68Å; W16-F26 AromaticContact CZ3-CD1 3.67Å; W16-F26 HydrophobicContact CZ3-CD1 3.67Å; W16-F26 HydrophobicContact CZ3-CE1 4.47Å; W16-F26 AromaticContact CZ3-CG 3.7Å; W16-F26 HydrophobicContact CZ3-CG 3.7Å; W16-F26 AromaticContact NE1-CE1 3.6Å; W16-A28 HydrophobicContact CB-CB 4.34Å; W16-A28 HydrophobicContact CG-CB 4.28Å; W16-T96 HydrophobicContact CH2-CG2 4.48Å; W16-T96 HydrophobicContact CZ3-CG2 4.07Å; W16-Y132 HydrophobicContact CH2-CD1 4.2Å; W16-Y132 HydrophobicContact CH2-CD2 4.31Å; W16-Y132 AromaticContact CH2-CE1 3.73Å; W16-Y132 HydrophobicContact CH2-CE1 3.73Å; W16-Y132 AromaticContact CH2-CE2 3.86Å; W16-Y132 HydrophobicContact CH2-CE2 3.86Å; W16-Y132 HydrophobicContact CH2-CG 4.47Å; W16-Y132 AromaticContact CH2-CZ 3.54Å; W16-Y132 AromaticContact CZ2-CE1 3.78Å; W16-Y132 HydrophobicContact CZ2-CE1 3.78Å; W16-Y132 HydrophobicContact CZ2-CE2 4.38Å; W16-Y132 AromaticContact CZ2-CZ 3.64Å; W16-Y132 WeakPolarHBondContact CZ2-OH 3.49Å
17N88.6Confident95.5Very high43 Ų4329 Ų2923%0.2314%0.137CC..Hα-helixtrans-70.8-39.3168.6-61139.1000110.9E13 S14 T15 E19 N20E13-N17 HydrophobicContact CG-CB 3.82Å; S14-N17 PolarHBondContact N-OD1 3.38Å; S14-N17 WeakPolarHBondContact O-CA 3.27Å; S14-N17 WeakPolarHBondContact O-CB 3.23Å; S14-N17 PolarHBondContact O-N 3.44Å; S14-N17 PolarHBondContact OG-N 3.08Å; S14-N17 PolarHBondContact OG-OD1 3.34Å; T15-N17 VanDerWaalsContact C-N 3.35Å; T15-N17 PolarHBondContact O-N 3.05Å; N17-E19 VanDerWaalsContact C-N 3.34Å; N17-N20 PolarHBondContact O-N 2.73Å; N17-N20 VanDerWaalsContact O-N 3.11Å
18Q89.3Confident95.5Very high105 Ų10529 Ų2949%0.49114%0.138SC..Hα-helixtrans-61.1-44174.7-65.3-178.1-37.500111.7E13 S14 T15 N20 S31E13-Q18 VanDerWaalsContact CD-CG 3.43Å; E13-Q18 HydrophobicContact CG-CG 3.88Å; E13-Q18 VanDerWaalsContact OE2-CD 3.28Å; E13-Q18 WeakPolarHBondContact OE2-CG 3.46Å; E13-Q18 PolarHBondContact OE2-NE2 3.43Å; S14-Q18 PolarHBondContact O-N 2.98Å; S14-Q18 VanDerWaalsContact O-N 3.15Å; T15-Q18 WeakPolarHBondContact O-CB 3.46Å; T15-Q18 PolarHBondContact O-N 3.49Å; Q18-N20 PolarHBondContact O-N 2.85Å; Q18-S31 PolarHBondContact NE2-OG 3.44Å; Q18-S31 VanDerWaalsContact NE2-OG 3.1Å
19E91.1Very high95.5Very high91 Ų9131.6 Ų31.643%0.42515%0.15SC..THydrogen-bonded Turntrans-76.24.3176.9-63.6175.4-142.400114T15 N17 R21 N99T15-E19 PolarHBondContact O-N 3.21Å; T15-E19 VanDerWaalsContact O-N 3.16Å; N17-E19 VanDerWaalsContact C-N 3.34Å; E19-R21 HydrophobicContact CB-CG 4.04Å; E19-R21 PolarHBondContact O-N 2.85Å; E19-R21 WeakPolarHBondContact OE2-CD 3.48Å; E19-R21 IonicContact OE2-CZ 2.78Å; E19-R21 IonicContact OE2-NE 3.87Å; E19-R21 PolarHBondContact OE2-NE 2.95Å; E19-R21 IonicContact OE2-NH2 3.62Å; E19-N99 PolarHBondContact O-ND2 2.81Å
20N89.3Confident95.5Very high65 Ų6532.4 Ų32.435%0.34815%0.154SC..THydrogen-bonded Turntrans54.135.1-177.5-164.736000114W16 N17 Q18 K100W16-N20 PolarHBondContact O-N 3.24Å; N17-N20 PolarHBondContact O-N 2.73Å; N17-N20 VanDerWaalsContact O-N 3.11Å; Q18-N20 PolarHBondContact O-N 2.85Å; N20-K100 WeakPolarHBondContact O-CG 3.31Å; N20-K100 PolarHBondContact O-N 3.25Å; N20-K100 WeakPolarHBondContact OD1-CD 3.4Å
21R93.5Very high95.5Very high85 Ų8531.2 Ų31.232%0.32115%0.15SC..BIsolated β-bridgetrans-94.5153.7178.4-65-179.3-172.7-95.3-0.5112.6W16 E19 C23 G97 L98W16-R21 HydrophobicContact CB-CB 4.21Å; W16-R21 HydrophobicContact CD2-CB 4.19Å; W16-R21 HydrophobicContact CE3-CB 4.01Å; W16-R21 HydrophobicContact CG-CB 4.28Å; W16-R21 PolarHBondContact O-N 2.87Å; E19-R21 HydrophobicContact CB-CG 4.04Å; E19-R21 PolarHBondContact O-N 2.85Å; E19-R21 WeakPolarHBondContact OE2-CD 3.48Å; E19-R21 IonicContact OE2-CZ 2.78Å; E19-R21 IonicContact OE2-NE 3.87Å; E19-R21 PolarHBondContact OE2-NE 2.95Å; E19-R21 IonicContact OE2-NH2 3.62Å; R21-C23 PolarHBondContact O-N 3.26Å; R21-G97 WeakPolarHBondContact CD-O 3.4Å; R21-G97 PolarHBondContact NH1-O 3.48Å; R21-L98 CarbonylContact C-O 3.6Å; R21-L98 VanDerWaalsContact CA-O 3.26Å; R21-L98 WeakPolarHBondContact CA-O 3.3Å
22F93.3Very high95.4Very high0 Ų039.1 Ų39.10%019%0.187CC..  trans-73105.9167-72.4-82.8000110.3W16 Y92 L95 T96 G97 L98 K100 T103 V112 R116W16-F22 WeakPolarHBondContact CZ3-O 3.44Å; F22-Y92 HydrophobicContact CB-CD2 4.24Å; F22-Y92 HydrophobicContact CB-CG 4.26Å; F22-Y92 AromaticContact CD1-CD1 3.74Å; F22-Y92 HydrophobicContact CD1-CD1 3.74Å; F22-Y92 HydrophobicContact CD1-CD2 4.09Å; F22-Y92 AromaticContact CD1-CE1 3.97Å; F22-Y92 HydrophobicContact CD1-CE1 3.97Å; F22-Y92 HydrophobicContact CD1-CE2 4.3Å; F22-Y92 AromaticContact CD1-CG 3.82Å; F22-Y92 HydrophobicContact CD1-CG 3.82Å; F22-Y92 HydrophobicContact CE1-CD1 4.18Å; F22-Y92 HydrophobicContact CE1-CE1 4.21Å; F22-Y92 HydrophobicContact CG-CG 4.47Å; F22-L95 HydrophobicContact CB-CB 4.4Å; F22-L95 VanDerWaalsContact CB-O 3.31Å; F22-L95 WeakPolarHBondContact CB-O 3.4Å; F22-L95 HydrophobicContact CD2-CB 4.04Å; F22-L95 HydrophobicContact CE1-CD1 4.37Å; F22-L95 HydrophobicContact CE2-CB 4.4Å; F22-L95 HydrophobicContact CE2-CD1 4.45Å; F22-L95 HydrophobicContact CG-CB 4.12Å; F22-L95 HydrophobicContact CZ-CD1 4.22Å; F22-T96 WeakPolarHBondContact O-CA 3.43Å; F22-G97 PolarHBondContact O-N 2.93Å; F22-L98 HydrophobicContact CD2-CB 4.45Å; F22-L98 WeakPolarHBondContact CD2-O 3.41Å; F22-L98 PolarHBondContact N-O 3.47Å; F22-K100 HydrophobicContact CD1-CG 4.37Å; F22-K100 HydrophobicContact CD2-CG 3.78Å; F22-K100 HydrophobicContact CE1-CG 4.16Å; F22-K100 HydrophobicContact CE2-CB 4.19Å; F22-K100 HydrophobicContact CE2-CG 3.54Å; F22-K100 HydrophobicContact CG-CG 4.2Å; F22-K100 HydrophobicContact CZ-CB 4.48Å; F22-K100 HydrophobicContact CZ-CG 3.75Å; F22-T103 HydrophobicContact CE2-CG2 4.38Å; F22-V112 HydrophobicContact CZ-CG1 4.21Å; F22-R116 HydrophobicContact CE1-CG 3.63Å; F22-R116 HydrophobicContact CZ-CG 3.9Å
23C95.1Very high95.4Very high7 Ų743.8 Ų43.85%0.04721%0.208CC..  trans-80.5-63-179.3-175.20000113W16 R21 W25 F26 A28 R62W16-C23 HydrophobicContact CB-CB 4.11Å; W16-C23 HydrophobicContact CE3-CB 4.05Å; R21-C23 PolarHBondContact O-N 3.26Å; C23-W25 PolarHBondContact O-N 3.21Å; C23-F26 WeakPolarHBondContact O-CB 3.35Å; C23-F26 PolarHBondContact O-N 2.81Å; C23-F26 VanDerWaalsContact O-N 3.15Å; C23-F26 PolarHBondContact SG-O 3.22Å; C23-A28 VanDerWaalsContact SG-CB 3.57Å; C23-R62 PolarHBondContact SG-NH1 3.23Å
24G96.5Very high95.5Very high1 Ų142.2 Ų42.21%0.0120%0.201CC..THydrogen-bonded Turntrans58-123.5-179.300000111R62 R90G24-R62 PolarHBondContact O-NH2 3.1Å; G24-R90 VanDerWaalsContact CA-O 3.28Å; G24-R90 WeakPolarHBondContact CA-O 3.4Å
25W98.6Very high95.6Very high2 Ų243.4 Ų43.41%0.00821%0.21CC..THydrogen-bonded Turntrans-86.1-3-177.1-75.435.6000114.6C23 D27 W85 N88 E89 H91 I136 Y142 L150 P151C23-W25 PolarHBondContact O-N 3.21Å; W25-D27 PolarHBondContact O-N 3.14Å; W25-W85 HydrophobicContact CH2-CD2 4.45Å; W25-W85 AromaticContact CH2-CE3 3.58Å; W25-W85 HydrophobicContact CH2-CE3 3.58Å; W25-W85 HydrophobicContact CH2-CZ3 4.08Å; W25-W85 AromaticContact CZ2-CE3 3.85Å; W25-W85 HydrophobicContact CZ2-CE3 3.85Å; W25-W85 HydrophobicContact CZ2-CZ3 4.22Å; W25-N88 HydrophobicContact CZ2-CB 4.23Å; W25-E89 PolarHBondContact NE1-O 2.95Å; W25-H91 AromaticContact CD1-CD2 3.91Å; W25-H91 AromaticContact CD1-CG 3.93Å; W25-H91 HydrophobicContact CD2-CB 4.38Å; W25-H91 AromaticContact CD2-CD2 3.38Å; W25-H91 AromaticContact CE2-CD2 3.78Å; W25-H91 AromaticContact CE3-CD2 3.76Å; W25-H91 HydrophobicContact CG-CB 4.18Å; W25-H91 AromaticContact CG-CD2 3.48Å; W25-H91 VanDerWaalsContact CG-CD2 3.48Å; W25-H91 AromaticContact CG-CG 3.9Å; W25-I136 HydrophobicContact CB-CG2 3.74Å; W25-I136 HydrophobicContact CE3-CG2 4.33Å; W25-Y142 AromaticContact CE3-CE1 3.84Å; W25-Y142 HydrophobicContact CE3-CE1 3.84Å; W25-Y142 HydrophobicContact CE3-CE2 4.12Å; W25-Y142 AromaticContact CE3-CZ 3.6Å; W25-Y142 HydrophobicContact CH2-CE1 4.32Å; W25-Y142 AromaticContact CZ3-CD1 3.84Å; W25-Y142 HydrophobicContact CZ3-CD1 3.84Å; W25-Y142 AromaticContact CZ3-CE1 3.48Å; W25-Y142 HydrophobicContact CZ3-CE1 3.48Å; W25-Y142 VanDerWaalsContact CZ3-CE1 3.48Å; W25-Y142 HydrophobicContact CZ3-CE2 4.34Å; W25-Y142 HydrophobicContact CZ3-CG 4.41Å; W25-Y142 AromaticContact CZ3-CZ 3.75Å; W25-L150 HydrophobicContact CE3-CD1 4.15Å; W25-L150 HydrophobicContact CH2-CD1 3.95Å; W25-L150 HydrophobicContact CZ3-CD1 3.3Å; W25-P151 HydrophobicContact CH2-CG 3.84Å; W25-P151 HydrophobicContact CZ2-CG 3.66Å
26F98.4Very high95.6Very high48 Ų4846.7 Ų46.721%0.21122%0.223CC..SBendtrans-60.8133.7168.3179.5-103.4000109.6W16 C23 A28 R62 T96 Y132 I136W16-F26 AromaticContact CD2-CD1 3.65Å; W16-F26 HydrophobicContact CD2-CD1 3.65Å; W16-F26 AromaticContact CD2-CE1 3.94Å; W16-F26 HydrophobicContact CD2-CE1 3.94Å; W16-F26 HydrophobicContact CD2-CG 4.5Å; W16-F26 AromaticContact CE2-CD1 3.41Å; W16-F26 VanDerWaalsContact CE2-CD1 3.41Å; W16-F26 AromaticContact CE2-CE1 3.29Å; W16-F26 HydrophobicContact CE3-CB 4.35Å; W16-F26 AromaticContact CE3-CD1 3.82Å; W16-F26 HydrophobicContact CE3-CD1 3.82Å; W16-F26 HydrophobicContact CE3-CG 4.3Å; W16-F26 HydrophobicContact CG-CD1 4.4Å; W16-F26 HydrophobicContact CG-CE1 4.5Å; W16-F26 HydrophobicContact CH2-CB 3.8Å; W16-F26 AromaticContact CH2-CD1 3.42Å; W16-F26 HydrophobicContact CH2-CD1 3.42Å; W16-F26 VanDerWaalsContact CH2-CD1 3.42Å; W16-F26 AromaticContact CH2-CD2 3.78Å; W16-F26 HydrophobicContact CH2-CD2 3.78Å; W16-F26 AromaticContact CH2-CE1 3.89Å; W16-F26 HydrophobicContact CH2-CE1 3.89Å; W16-F26 HydrophobicContact CH2-CE2 4.2Å; W16-F26 AromaticContact CH2-CG 3.36Å; W16-F26 HydrophobicContact CH2-CG 3.36Å; W16-F26 HydrophobicContact CH2-CZ 4.26Å; W16-F26 AromaticContact CZ2-CD1 3.32Å; W16-F26 HydrophobicContact CZ2-CD1 3.32Å; W16-F26 HydrophobicContact CZ2-CD2 4.01Å; W16-F26 AromaticContact CZ2-CE1 3.29Å; W16-F26 HydrophobicContact CZ2-CE1 3.29Å; W16-F26 AromaticContact CZ2-CE2 3.97Å; W16-F26 HydrophobicContact CZ2-CE2 3.97Å; W16-F26 AromaticContact CZ2-CG 3.7Å; W16-F26 HydrophobicContact CZ2-CG 3.7Å; W16-F26 AromaticContact CZ2-CZ 3.62Å; W16-F26 HydrophobicContact CZ2-CZ 3.62Å; W16-F26 HydrophobicContact CZ3-CB 3.68Å; W16-F26 AromaticContact CZ3-CD1 3.67Å; W16-F26 HydrophobicContact CZ3-CD1 3.67Å; W16-F26 HydrophobicContact CZ3-CE1 4.47Å; W16-F26 AromaticContact CZ3-CG 3.7Å; W16-F26 HydrophobicContact CZ3-CG 3.7Å; W16-F26 AromaticContact NE1-CE1 3.6Å; C23-F26 WeakPolarHBondContact O-CB 3.35Å; C23-F26 PolarHBondContact O-N 2.81Å; C23-F26 VanDerWaalsContact O-N 3.15Å; C23-F26 PolarHBondContact SG-O 3.22Å; F26-A28 HydrophobicContact CD1-CB 3.77Å; F26-A28 HydrophobicContact CE1-CB 3.93Å; F26-A28 PolarHBondContact O-N 2.91Å; F26-R62 PolarHBondContact O-NH1 3.35Å; F26-T96 HydrophobicContact CB-CG2 4.11Å; F26-Y132 AromaticContact CD2-CD1 3.6Å; F26-Y132 HydrophobicContact CD2-CD1 3.6Å; F26-Y132 AromaticContact CD2-CE1 3.92Å; F26-Y132 HydrophobicContact CD2-CE1 3.92Å; F26-Y132 HydrophobicContact CD2-CG 4.43Å; F26-Y132 AromaticContact CE2-CD1 3.72Å; F26-Y132 HydrophobicContact CE2-CD1 3.72Å; F26-Y132 AromaticContact CE2-CE1 3.68Å; F26-Y132 HydrophobicContact CE2-CE1 3.68Å; F26-Y132 HydrophobicContact CZ-CE1 4.39Å; F26-I136 HydrophobicContact CB-CD1 4.14Å
27D98.4Very high95.7Very high30 Ų3046.4 Ų46.416%0.1622%0.222CC..  trans-84.552.8-172.5-159.820.6000112W25 L60 K61 R141W25-D27 PolarHBondContact O-N 3.14Å; D27-L60 WeakPolarHBondContact OD1-CA 3.41Å; D27-K61 WeakPolarHBondContact O-CD 3.49Å; D27-K61 WeakPolarHBondContact O-CE 3.38Å; D27-K61 PolarHBondContact O-NZ 3.09Å; D27-K61 WeakPolarHBondContact OD1-CG 3.23Å; D27-K61 PolarHBondContact OD1-N 2.71Å; D27-K61 WeakPolarHBondContact OD2-CE 3.44Å; D27-K61 IonicContact OD2-NZ 2.91Å; D27-R141 VanDerWaalsContact CG-NH1 3.28Å; D27-R141 IonicContact OD1-NH1 2.7Å; D27-R141 IonicContact OD2-CZ 3.84Å; D27-R141 IonicContact OD2-NH1 2.98Å; D27-R141 PolarHBondContact OD2-NH1 3.39Å; D27-R141 IonicContact OD2-NH2 3.87Å; D27-R141 PolarHBondContact OD2-NH2 3.46Å
28A97.9Very high96.2Very high2 Ų244.4 Ų44.42%0.01721%0.211CC..PPolyproline II helixtrans-59.6142.9177.500000111.4W16 C23 F26W16-A28 HydrophobicContact CB-CB 4.34Å; W16-A28 HydrophobicContact CG-CB 4.28Å; C23-A28 VanDerWaalsContact SG-CB 3.57Å; F26-A28 HydrophobicContact CD1-CB 3.77Å; F26-A28 HydrophobicContact CE1-CB 3.93Å; F26-A28 PolarHBondContact O-N 2.91Å
29E98.4Very high96.6Very high54 Ų5446.9 Ų46.925%0.25222%0.216SC..PPolyproline II helixtrans-78.5158.1174.3-164.554.1-81.300111.7S14 T15 K61 R65S14-E29 VanDerWaalsContact CA-O 3.3Å; S14-E29 WeakPolarHBondContact CA-O 3.43Å; S14-E29 VanDerWaalsContact CB-O 3.29Å; S14-E29 WeakPolarHBondContact CB-O 3.5Å; T15-E29 PolarHBondContact N-O 3.29Å; T15-E29 PolarHBondContact OG1-O 3.04Å; E29-K61 HydrophobicContact CB-CD 4.32Å; E29-K61 VanDerWaalsContact OE2-CD 3.28Å; E29-K61 WeakPolarHBondContact OE2-CD 3.21Å; E29-R65 WeakPolarHBondContact OE1-CD 3.17Å; E29-R65 IonicContact OE1-NE 2.79Å; E29-R65 PolarHBondContact OE1-NE 3.38Å; E29-R65 IonicContact OE2-CZ 2.62Å; E29-R65 VanDerWaalsContact OE2-CZ 3.23Å; E29-R65 IonicContact OE2-NE 3.14Å; E29-R65 PolarHBondContact OE2-NE 2.84Å; E29-R65 IonicContact OE2-NH2 2.72Å; E29-R65 PolarHBondContact OE2-NH2 2.87Å
30L98.4Very high96.9Very high18 Ų1846.7 Ų46.79%0.09421%0.211CC..BIsolated β-bridgetrans-59143.6163.4-68.3174.7000110H11 G12 R62 R65H11-L30 HydrophobicContact CB-CD2 4.44Å; G12-L30 VanDerWaalsContact O-CD2 3.29Å; G12-L30 WeakPolarHBondContact O-CD2 3.34Å; L30-R62 HydrophobicContact CD2-CB 3.88Å; L30-R62 HydrophobicContact CG-CB 4.09Å; L30-R65 HydrophobicContact CD1-CB 3.82Å
31S98.1Very high97.4Very high6 Ų643.6 Ų43.64%0.04220%0.195CC..PPolyproline II helixtrans-75.2171.4163.566.70000110.5E13 Q18 K33 G34 A35E13-S31 PolarHBondContact O-N 3.06Å; E13-S31 PolarHBondContact O-OG 2.81Å; E13-S31 PolarHBondContact OE2-OG 2.92Å; Q18-S31 PolarHBondContact NE2-OG 3.44Å; Q18-S31 VanDerWaalsContact NE2-OG 3.1Å; S31-K33 VanDerWaalsContact C-N 3.29Å; S31-K33 PolarHBondContact O-N 3.23Å; S31-G34 PolarHBondContact O-N 3.42Å; S31-G34 VanDerWaalsContact O-N 3.08Å; S31-G34 PolarHBondContact OG-N 3.12Å; S31-A35 PolarHBondContact O-N 2.86Å
32E97.8Very high97.6Very high170 Ų17039.7 Ų39.779%0.79418%0.181SC*.Hα-helixtrans-55.4-48172-66.8-179.1170.400111G34 A35 E36E32-G34 VanDerWaalsContact C-N 3.33Å; E32-G34 PolarHBondContact O-N 3.12Å; E32-A35 WeakPolarHBondContact O-CB 3.48Å; E32-A35 PolarHBondContact O-N 3.14Å; E32-A35 VanDerWaalsContact O-N 3.14Å; E32-E36 PolarHBondContact O-N 3.39Å
33K96.4Very high97.8Very high99 Ų9945.3 Ų45.343%0.4321%0.205SC..Hα-helixtrans-56.5-45172.6177.5176.4162.3-152.30111.8E13 S31 A35 E36 E37E13-K33 IonicContact OE1-NZ 3.26Å; E13-K33 PolarHBondContact OE1-NZ 3.26Å; E13-K33 WeakPolarHBondContact OE2-CD 3.31Å; E13-K33 IonicContact OE2-NZ 2.62Å; S31-K33 VanDerWaalsContact C-N 3.29Å; S31-K33 PolarHBondContact O-N 3.23Å; K33-A35 VanDerWaalsContact C-N 3.3Å; K33-A35 PolarHBondContact O-N 2.99Å; K33-E36 WeakPolarHBondContact O-CB 3.41Å; K33-E36 PolarHBondContact O-N 3.18Å; K33-E37 WeakPolarHBondContact CE-OE1 3.45Å; K33-E37 HydrophobicContact CG-CG 4.43Å; K33-E37 VanDerWaalsContact O-CG 3.29Å; K33-E37 WeakPolarHBondContact O-CG 3.41Å; K33-E37 PolarHBondContact O-N 2.88Å
34G97.6Very high98Very high0 Ų045.6 Ų45.60%021%0.208CC..Hα-helixtrans-63.1-34.3177.500000114E13 S31 E32 E37 A38E13-G34 VanDerWaalsContact O-CA 3.32Å; E13-G34 WeakPolarHBondContact O-CA 3.48Å; S31-G34 PolarHBondContact O-N 3.42Å; S31-G34 VanDerWaalsContact O-N 3.08Å; S31-G34 PolarHBondContact OG-N 3.12Å; E32-G34 VanDerWaalsContact C-N 3.33Å; E32-G34 PolarHBondContact O-N 3.12Å; G34-E37 PolarHBondContact O-N 3.42Å; G34-A38 PolarHBondContact O-N 3.12Å; G34-A38 VanDerWaalsContact O-N 3.08Å
35A98.4Very high98.1Very high25 Ų2545.5 Ų45.521%0.20721%0.208CC..Hα-helixtrans-68.1-40.3173.300000111.6S31 E32 K33 A38 R39S31-A35 PolarHBondContact O-N 2.86Å; E32-A35 WeakPolarHBondContact O-CB 3.48Å; E32-A35 PolarHBondContact O-N 3.14Å; E32-A35 VanDerWaalsContact O-N 3.14Å; K33-A35 VanDerWaalsContact C-N 3.3Å; K33-A35 PolarHBondContact O-N 2.99Å; A35-A38 PolarHBondContact O-N 3.23Å; A35-R39 WeakPolarHBondContact O-CG 3.45Å; A35-R39 PolarHBondContact O-N 2.84Å
36E97.8Very high98.1Very high112 Ų11251.4 Ų51.452%0.52323%0.233SC..Hα-helixtrans-64.3-41172.8-68.1175.9170.200112.6E32 K33 A38 R39 R40E32-E36 PolarHBondContact O-N 3.39Å; K33-E36 WeakPolarHBondContact O-CB 3.41Å; K33-E36 PolarHBondContact O-N 3.18Å; E36-A38 VanDerWaalsContact C-N 3.29Å; E36-A38 PolarHBondContact O-N 3.12Å; E36-R39 PolarHBondContact O-N 2.7Å; E36-R40 WeakPolarHBondContact O-CB 3.27Å; E36-R40 PolarHBondContact O-N 3.09Å
37E97.3Very high98Very high12 Ų1253.8 Ų53.86%0.05625%0.248CC..Hα-helixtrans-57.2-43.8173.3-71.5-179.6164.600111.1G12 E13 K33 G34 R40 G41 T212G12-E37 WeakPolarHBondContact CA-OE2 3.48Å; E13-E37 PolarHBondContact N-OE2 3.43Å; K33-E37 WeakPolarHBondContact CE-OE1 3.45Å; K33-E37 HydrophobicContact CG-CG 4.43Å; K33-E37 VanDerWaalsContact O-CG 3.29Å; K33-E37 WeakPolarHBondContact O-CG 3.41Å; K33-E37 PolarHBondContact O-N 2.88Å; G34-E37 PolarHBondContact O-N 3.42Å; E37-R40 PolarHBondContact O-N 2.98Å; E37-G41 PolarHBondContact O-N 2.96Å; E37-T212 PolarHBondContact OE1-OG1 3.1Å; E37-T212 WeakPolarHBondContact OE2-CB 3.36Å; E37-T212 PolarHBondContact OE2-OG1 3.24Å; E37-T212 VanDerWaalsContact OE2-OG1 3.05Å
38A98.3Very high98Very high0 Ų054.4 Ų54.40%026%0.257CS..Hα-helixtrans-64.3-42.8176.100000112.7G34 A35 E36 R40 G41 A42 T66 A69G34-A38 PolarHBondContact O-N 3.12Å; G34-A38 VanDerWaalsContact O-N 3.08Å; A35-A38 PolarHBondContact O-N 3.23Å; E36-A38 VanDerWaalsContact C-N 3.29Å; E36-A38 PolarHBondContact O-N 3.12Å; A38-R40 VanDerWaalsContact C-N 3.35Å; A38-G41 PolarHBondContact O-N 2.88Å; A38-A42 PolarHBondContact O-N 3.42Å; A38-T66 HydrophobicContact CB-CG2 3.99Å; A38-A69 HydrophobicContact CB-CB 3.84Å
39R98.4Very high98Very high157 Ų15763 Ų6359%0.59230%0.295SS*.Hα-helixtrans-64.1-38.1175.2-68.1-177.9-161.9114.6-1.2112.2A35 E36 A42 K43A35-R39 WeakPolarHBondContact O-CG 3.45Å; A35-R39 PolarHBondContact O-N 2.84Å; E36-R39 PolarHBondContact O-N 2.7Å; R39-A42 VanDerWaalsContact O-CB 3.32Å; R39-A42 WeakPolarHBondContact O-CB 3.36Å; R39-A42 PolarHBondContact O-N 3.24Å; R39-K43 PolarHBondContact O-N 3.26Å
40R97.8Very high98Very high87 Ų8761.3 Ų61.333%0.32829%0.287SS..Hα-helixtrans-65.2-42.7175.4-173.7174.261.7-112.41.9111.3E36 E37 A38 A42 K43 A44 T238E36-R40 WeakPolarHBondContact O-CB 3.27Å; E36-R40 PolarHBondContact O-N 3.09Å; E37-R40 PolarHBondContact O-N 2.98Å; A38-R40 VanDerWaalsContact C-N 3.35Å; R40-A42 VanDerWaalsContact C-N 3.32Å; R40-A42 PolarHBondContact O-N 2.89Å; R40-K43 PolarHBondContact O-N 3.02Å; R40-A44 PolarHBondContact O-N 3.5Å; R40-T238 VanDerWaalsContact NE-CG2 3.33Å
41G98.1Very high97.9Very high1 Ų165.6 Ų65.61%0.0131%0.306CS..Hα-helixtrans-59.3-42171.700000112.5E37 A38 A44 I45E37-G41 PolarHBondContact O-N 2.96Å; A38-G41 PolarHBondContact O-N 2.88Å; G41-A44 PolarHBondContact O-N 2.94Å; G41-I45 WeakPolarHBondContact O-CG1 3.34Å; G41-I45 PolarHBondContact O-N 3.33Å
42A98.6Very high98Very high2 Ų265.5 Ų65.52%0.01731%0.305CS..Hα-helixtrans-58.9-4717400000111.9A38 R39 R40 A44 I45 K46 A69 I70 T74A38-A42 PolarHBondContact O-N 3.42Å; R39-A42 VanDerWaalsContact O-CB 3.32Å; R39-A42 WeakPolarHBondContact O-CB 3.36Å; R39-A42 PolarHBondContact O-N 3.24Å; R40-A42 VanDerWaalsContact C-N 3.32Å; R40-A42 PolarHBondContact O-N 2.89Å; A42-A44 PolarHBondContact O-N 3.22Å; A42-I45 PolarHBondContact O-N 3.04Å; A42-K46 WeakPolarHBondContact O-CB 3.39Å; A42-K46 PolarHBondContact O-N 2.91Å; A42-A69 WeakPolarHBondContact CB-O 3.43Å; A42-I70 HydrophobicContact CB-CB 4.45Å; A42-I70 HydrophobicContact CB-CG1 4.3Å; A42-T74 WeakPolarHBondContact O-CG2 3.5Å
43K98.2Very high98Very high118 Ų11859.8 Ų59.851%0.51328%0.28SS..Hα-helixtrans-59.4-46.5176.5-168.4-167.1-177.9-50.30111.4R39 R40 I45 K46 D47R39-K43 PolarHBondContact O-N 3.26Å; R40-K43 PolarHBondContact O-N 3.02Å; K43-I45 VanDerWaalsContact C-N 3.31Å; K43-I45 PolarHBondContact O-N 3.19Å; K43-K46 WeakPolarHBondContact O-CB 3.35Å; K43-K46 PolarHBondContact O-N 2.67Å; K43-K46 VanDerWaalsContact O-N 3.16Å; K43-D47 IonicContact NZ-OD1 2.77Å; K43-D47 PolarHBondContact NZ-OD1 3.04Å; K43-D47 IonicContact NZ-OD2 3.01Å; K43-D47 PolarHBondContact NZ-OD2 2.84Å; K43-D47 WeakPolarHBondContact O-CB 3Å; K43-D47 PolarHBondContact O-N 3.1Å
44A98Very high98.1Very high13 Ų1355.6 Ų55.611%0.10726%0.262CS..Hα-helixtrans-61-40.2179.500000112.4R40 G41 A42 A48 L233R40-A44 PolarHBondContact O-N 3.5Å; G41-A44 PolarHBondContact O-N 2.94Å; A42-A44 PolarHBondContact O-N 3.22Å; A44-A48 VanDerWaalsContact O-CB 3.3Å; A44-A48 WeakPolarHBondContact O-CB 3.33Å; A44-A48 PolarHBondContact O-N 3.49Å; A44-A48 VanDerWaalsContact O-N 3.08Å; A44-L233 HydrophobicContact CB-CB 4.04Å
45I98.5Very high98.2Very high0 Ų055.6 Ų55.60%026%0.262CS..Hα-helixtrans-64.6-44.2174.5-71.1169.6000111V7 G41 A42 K43 A48 K49 M50 F52 I70 T74 P215 L233V7-I45 HydrophobicContact CG1-CD1 4.48Å; G41-I45 WeakPolarHBondContact O-CG1 3.34Å; G41-I45 PolarHBondContact O-N 3.33Å; A42-I45 PolarHBondContact O-N 3.04Å; K43-I45 VanDerWaalsContact C-N 3.31Å; K43-I45 PolarHBondContact O-N 3.19Å; I45-A48 CarbonylContact O-C 3.47Å; I45-A48 PolarHBondContact O-N 2.91Å; I45-K49 PolarHBondContact O-N 3.42Å; I45-M50 HydrophobicContact CG2-CB 3.9Å; I45-M50 PolarHBondContact O-N 3.48Å; I45-M50 VanDerWaalsContact O-N 3.09Å; I45-F52 HydrophobicContact CD1-CE2 4.46Å; I45-F52 HydrophobicContact CD1-CZ 4.36Å; I45-F52 HydrophobicContact CG2-CE2 3.56Å; I45-F52 HydrophobicContact CG2-CZ 3.83Å; I45-I70 HydrophobicContact CD1-CD1 4.37Å; I45-I70 HydrophobicContact CD1-CG1 4.43Å; I45-I70 HydrophobicContact CD1-CG2 3.59Å; I45-T74 HydrophobicContact CB-CG2 4.03Å; I45-T74 HydrophobicContact CG2-CG2 3.6Å; I45-P215 HydrophobicContact CD1-CB 4.07Å; I45-P215 HydrophobicContact CD1-CG 3.78Å; I45-P215 HydrophobicContact CG1-CB 4.03Å; I45-P215 HydrophobicContact CG1-CG 3.72Å; I45-L233 HydrophobicContact CG1-CD1 4.26Å
46K98.4Very high98.2Very high126 Ų12654.5 Ų54.555%0.54825%0.253SS..Hα-helixtrans-62.6-48177.6-174.5-177.6-169.1160.30111.9A42 K43 A48 K49 G73 T74A42-K46 WeakPolarHBondContact O-CB 3.39Å; A42-K46 PolarHBondContact O-N 2.91Å; K43-K46 WeakPolarHBondContact O-CB 3.35Å; K43-K46 PolarHBondContact O-N 2.67Å; K43-K46 VanDerWaalsContact O-N 3.16Å; K46-A48 PolarHBondContact O-N 3.2Å; K46-K49 WeakPolarHBondContact O-CA 3.46Å; K46-K49 PolarHBondContact O-N 2.99Å; K46-G73 WeakPolarHBondContact CD-O 3.4Å; K46-T74 HydrophobicContact CB-CG2 4.14Å
47D97.7Very high98.3Very high97 Ų9749.2 Ų49.252%0.51923%0.228SC..Hα-helixtrans-60.7-37.5179.1-66.4-18.2000110.8K43 K49K43-D47 IonicContact NZ-OD1 2.77Å; K43-D47 PolarHBondContact NZ-OD1 3.04Å; K43-D47 IonicContact NZ-OD2 3.01Å; K43-D47 PolarHBondContact NZ-OD2 2.84Å; K43-D47 WeakPolarHBondContact O-CB 3Å; K43-D47 PolarHBondContact O-N 3.1Å; D47-K49 PolarHBondContact O-N 3.47Å
48A97.4Very high98.4Very high43 Ų4348.6 Ų48.636%0.35523%0.225SC..THydrogen-bonded Turntrans-761.6173.900000114.1A44 I45 K46 M50 L233A44-A48 VanDerWaalsContact O-CB 3.3Å; A44-A48 WeakPolarHBondContact O-CB 3.33Å; A44-A48 PolarHBondContact O-N 3.49Å; A44-A48 VanDerWaalsContact O-N 3.08Å; I45-A48 CarbonylContact O-C 3.47Å; I45-A48 PolarHBondContact O-N 2.91Å; K46-A48 PolarHBondContact O-N 3.2Å; A48-M50 HydrophobicContact CB-CE 4.12Å; A48-M50 HydrophobicContact CB-CG 3.99Å; A48-M50 PolarHBondContact O-N 2.82Å; A48-L233 HydrophobicContact CB-CD1 4.4Å
49K97.9Very high98.4Very high184 Ų18449.7 Ų49.780%0.823%0.232SC*.THydrogen-bonded Turntrans50.841.2-179.4-56.9179.8-178.3179.70112.4I45 K46 D47I45-K49 PolarHBondContact O-N 3.42Å; K46-K49 WeakPolarHBondContact O-CA 3.46Å; K46-K49 PolarHBondContact O-N 2.99Å; D47-K49 PolarHBondContact O-N 3.47Å
50M97.9Very high98.4Very high18 Ų1842.2 Ų42.29%0.08920%0.204CC..  trans-87.5120.4179.7-68.4-163.2-176.600111V7 I45 A48 F52 Q76 V217 L233V7-M50 HydrophobicContact CG2-SD 3.84Å; I45-M50 HydrophobicContact CG2-CB 3.9Å; I45-M50 PolarHBondContact O-N 3.48Å; I45-M50 VanDerWaalsContact O-N 3.09Å; A48-M50 HydrophobicContact CB-CE 4.12Å; A48-M50 HydrophobicContact CB-CG 3.99Å; A48-M50 PolarHBondContact O-N 2.82Å; M50-F52 HydrophobicContact CB-CZ 4.21Å; M50-Q76 PolarHBondContact O-NE2 3.01Å; M50-V217 HydrophobicContact CE-CG1 4.22Å; M50-V217 HydrophobicContact CE-CG2 3.83Å; M50-V217 HydrophobicContact SD-CG2 4.27Å; M50-L233 HydrophobicContact CE-CD1 3.64Å; M50-L233 HydrophobicContact CE-CD2 4.08Å; M50-L233 HydrophobicContact CE-CG 4.43Å; M50-L233 HydrophobicContact SD-CD1 3.71Å
51E98.3Very high98.5Very high108 Ų10841.7 Ų41.751%0.50520%0.204SC..  trans-102.3153.7171.5-67.4172.2-173.100110.6Q76 R180E51-Q76 VanDerWaalsContact CA-OE1 3.28Å; E51-R180 VanDerWaalsContact CB-CZ 3.42Å; E51-R180 WeakPolarHBondContact O-CB 3.45Å; E51-R180 WeakPolarHBondContact O-CD 3.29Å; E51-R180 PolarHBondContact O-NE 2.73Å; E51-R180 IonicContact OE2-CZ 2.77Å; E51-R180 IonicContact OE2-NH1 2.85Å; E51-R180 PolarHBondContact OE2-NH1 3.1Å; E51-R180 IonicContact OE2-NH2 3.51Å; E51-R180 PolarHBondContact OE2-NH2 3.33Å
52F98.8Very high98.5Very high3 Ų341.8 Ų41.81%0.01320%0.204CC..  trans-129.2161.4179.9-54.3-70.1000111.1V7 I45 M50 L79 R180 L182V7-F52 HydrophobicContact CB-CE1 3.73Å; V7-F52 HydrophobicContact CB-CZ 4.04Å; V7-F52 HydrophobicContact CG1-CZ 4.34Å; V7-F52 HydrophobicContact CG2-CE1 3.58Å; V7-F52 HydrophobicContact CG2-CZ 3.96Å; I45-F52 HydrophobicContact CD1-CE2 4.46Å; I45-F52 HydrophobicContact CD1-CZ 4.36Å; I45-F52 HydrophobicContact CG2-CE2 3.56Å; I45-F52 HydrophobicContact CG2-CZ 3.83Å; M50-F52 HydrophobicContact CB-CZ 4.21Å; F52-L79 HydrophobicContact CB-CD1 3.63Å; F52-L79 WeakPolarHBondContact O-CD1 3.31Å; F52-L79 WeakPolarHBondContact O-CD2 3.32Å; F52-R180 WeakPolarHBondContact CA-O 3.41Å; F52-L182 HydrophobicContact CB-CB 4.5Å; F52-L182 HydrophobicContact CD1-CB 3.76Å; F52-L182 HydrophobicContact CD2-CB 4.19Å; F52-L182 HydrophobicContact CD2-CD2 4.08Å; F52-L182 HydrophobicContact CE1-CB 3.96Å; F52-L182 HydrophobicContact CE1-CD1 4.47Å; F52-L182 HydrophobicContact CE2-CB 4.34Å; F52-L182 HydrophobicContact CE2-CD2 3.95Å; F52-L182 HydrophobicContact CG-CB 3.88Å; F52-L182 HydrophobicContact CZ-CB 4.24Å; F52-L182 HydrophobicContact CZ-CD1 4.19Å; F52-L182 HydrophobicContact CZ-CD2 4.39Å
53D98.8Very high98.5Very high50 Ų5041.7 Ų41.727%0.26720%0.203SC..SBendtrans-121.4-19.8179.9-49.8-60.6000112P80 K179 R180D53-P80 WeakPolarHBondContact O-CD 3.48Å; D53-P80 WeakPolarHBondContact O-CG 3.38Å; D53-K179 HydrophobicContact CB-CB 4.02Å; D53-K179 HydrophobicContact CB-CD 4.28Å; D53-K179 HydrophobicContact CB-CG 4.17Å; D53-R180 PolarHBondContact N-O 3.11Å; D53-R180 IonicContact OD1-CZ 3.58Å; D53-R180 IonicContact OD1-NE 3.44Å; D53-R180 PolarHBondContact OD1-NE 3.5Å; D53-R180 IonicContact OD1-NH2 2.81Å; D53-R180 PolarHBondContact OD1-NH2 3.25Å; D53-R180 VanDerWaalsContact OD2-CB 3.31Å; D53-R180 WeakPolarHBondContact OD2-CB 3.47Å; D53-R180 WeakPolarHBondContact OD2-CG 3.44Å; D53-R180 IonicContact OD2-CZ 3.8Å; D53-R180 PolarHBondContact OD2-N 3.29Å; D53-R180 IonicContact OD2-NE 3.23Å; D53-R180 PolarHBondContact OD2-NE 3.3Å; D53-R180 IonicContact OD2-NH2 3.43Å
54I98.9Very high98.5Very high12 Ų1237.1 Ų37.16%0.06218%0.184CC..EExtended strand (participates in β ladder)trans-156.4145176-171.6162.8000111.1Y56 P80 V82 Q174 K179 V181 L182I54-Y56 HydrophobicContact CD1-CE1 4.49Å; I54-Y56 HydrophobicContact CD1-CE2 4.3Å; I54-Y56 HydrophobicContact CG1-CE2 4.13Å; I54-Y56 HydrophobicContact CG2-CE2 3.97Å; I54-P80 HydrophobicContact CB-CG 4.32Å; I54-P80 HydrophobicContact CG1-CG 4.24Å; I54-V82 HydrophobicContact CD1-CG2 4.26Å; I54-Q174 HydrophobicContact CD1-CG 4.3Å; I54-Q174 HydrophobicContact CG2-CB 4.28Å; I54-Q174 HydrophobicContact CG2-CG 4.41Å; I54-K179 HydrophobicContact CG2-CB 4.44Å; I54-K179 HydrophobicContact CG2-CD 4.28Å; I54-V181 HydrophobicContact CG2-CG2 3.82Å; I54-L182 PolarHBondContact O-N 3.05Å; I54-L182 VanDerWaalsContact O-N 3.12Å
55C98.9Very high98.6Very high0 Ų041.9 Ų41.90%020%0.199CC..EExtended strand (participates in β ladder)trans-122.5143179.8-54.30000112.1L67 P80 V81 V82 L182C55-L67 HydrophobicContact CB-CD1 3.84Å; C55-L67 HydrophobicContact CB-CD2 3.8Å; C55-L67 HydrophobicContact CB-CG 4.4Å; C55-P80 PolarHBondContact N-O 2.78Å; C55-V81 HydrophobicContact CB-CG2 4.21Å; C55-V81 WeakPolarHBondContact O-CA 3.44Å; C55-V82 PolarHBondContact O-N 3.47Å; C55-L182 CarbonylContact C-O 3.52Å; C55-L182 VanDerWaalsContact CA-O 3.27Å; C55-L182 WeakPolarHBondContact CA-O 3.33Å
56Y98.9Very high98.6Very high2 Ų241.9 Ų41.91%0.00820%0.199CC..EExtended strand (participates in β ladder)trans-122.2140.9175.7-63.7-82.8000110.7I54 V82 F166 E170 I171 Q174 V181 L182 I183 A184I54-Y56 HydrophobicContact CD1-CE1 4.49Å; I54-Y56 HydrophobicContact CD1-CE2 4.3Å; I54-Y56 HydrophobicContact CG1-CE2 4.13Å; I54-Y56 HydrophobicContact CG2-CE2 3.97Å; Y56-V82 WeakPolarHBondContact CA-O 3.31Å; Y56-V82 HydrophobicContact CD1-CB 3.64Å; Y56-V82 HydrophobicContact CD1-CG1 4.05Å; Y56-V82 HydrophobicContact CD1-CG2 4.38Å; Y56-V82 HydrophobicContact CE1-CB 3.73Å; Y56-V82 HydrophobicContact CE1-CG1 4.05Å; Y56-V82 HydrophobicContact CE1-CG2 4Å; Y56-F166 AromaticContact CD1-CE1 3.63Å; Y56-F166 HydrophobicContact CD1-CE1 3.63Å; Y56-F166 AromaticContact CD1-CZ 3.59Å; Y56-F166 HydrophobicContact CD1-CZ 3.59Å; Y56-F166 HydrophobicContact CE1-CE1 4.1Å; Y56-F166 AromaticContact CE1-CZ 3.82Å; Y56-F166 HydrophobicContact CE1-CZ 3.82Å; Y56-F166 HydrophobicContact CG-CE1 4.35Å; Y56-E170 PolarHBondContact OH-O 3.2Å; Y56-I171 HydrophobicContact CD1-CD1 4.5Å; Y56-I171 HydrophobicContact CD1-CG1 4.21Å; Y56-I171 HydrophobicContact CD2-CD1 4.19Å; Y56-I171 HydrophobicContact CD2-CG1 4.01Å; Y56-I171 HydrophobicContact CE1-CG1 4.11Å; Y56-I171 HydrophobicContact CE2-CB 4.37Å; Y56-I171 HydrophobicContact CE2-CG1 3.89Å; Y56-I171 HydrophobicContact CE2-CG2 4.22Å; Y56-I171 HydrophobicContact CG-CD1 4.15Å; Y56-I171 HydrophobicContact CG-CG1 4.16Å; Y56-Q174 WeakPolarHBondContact OH-CG 3.37Å; Y56-V181 HydrophobicContact CD2-CG1 3.58Å; Y56-V181 HydrophobicContact CE2-CG1 3.72Å; Y56-L182 PolarHBondContact N-O 2.97Å; Y56-I183 HydrophobicContact CD2-CG1 4.46Å; Y56-I183 CarbonylContact O-C 3.58Å; Y56-I183 WeakPolarHBondContact O-CA 3.39Å; Y56-A184 PolarHBondContact O-N 2.88Å
57T98.9Very high98.6Very high0 Ų035.9 Ų35.90%017%0.173CC..EExtended strand (participates in β ladder)trans-148.7170.1172.1-167.80000111.8A63 I64 L67 V81 V82 R83 T84 A184T57-A63 WeakPolarHBondContact OG1-CB 3.38Å; T57-I64 HydrophobicContact CG2-CG1 3.78Å; T57-L67 HydrophobicContact CG2-CD2 3.94Å; T57-V81 HydrophobicContact CG2-CG1 4.12Å; T57-V82 PolarHBondContact N-O 3.24Å; T57-R83 HydrophobicContact CG2-CG 3.67Å; T57-R83 WeakPolarHBondContact O-CA 3.34Å; T57-T84 PolarHBondContact O-N 2.87Å; T57-A184 VanDerWaalsContact CA-O 3.23Å; T57-A184 WeakPolarHBondContact CA-O 3.43Å; T57-A184 VanDerWaalsContact CB-O 3.27Å; T57-A184 WeakPolarHBondContact CB-O 3.07Å; T57-A184 PolarHBondContact OG1-O 3.08Å
58S98.9Very high98.7Very high0 Ų036.9 Ų36.90%017%0.17CC..  trans-74.4-177.6174.478.70000111.5L60 A63 T84 L87 N88 H186S58-L60 VanDerWaalsContact C-N 3.3Å; S58-L60 PolarHBondContact OG-N 2.84Å; S58-L60 VanDerWaalsContact OG-N 3.08Å; S58-A63 WeakPolarHBondContact OG-CB 3.06Å; S58-T84 VanDerWaalsContact CA-O 3.3Å; S58-T84 WeakPolarHBondContact CA-O 3.41Å; S58-L87 VanDerWaalsContact CB-C 3.48Å; S58-L87 VanDerWaalsContact CB-O 3.3Å; S58-L87 WeakPolarHBondContact CB-O 3.31Å; S58-N88 WeakPolarHBondContact CB-OD1 3.21Å; S58-H186 WeakPolarHBondContact CB-NE2 3.16Å; S58-H186 PolarHBondContact OG-NE2 2.78Å
59V98.9Very high98.8Very high23 Ų2336 Ų3614%0.13916%0.162CC..SBendtrans-9313.7169.7-60.40000112.6R83 T84 W85 N88 R141 Y142V59-R83 HydrophobicContact CG1-CB 4.33Å; V59-T84 PolarHBondContact N-O 3.43Å; V59-W85 HydrophobicContact CG2-CB 4.17Å; V59-N88 VanDerWaalsContact CG2-OD1 3.26Å; V59-N88 WeakPolarHBondContact CG2-OD1 3.4Å; V59-N88 PolarHBondContact N-OD1 2.97Å; V59-N88 VanDerWaalsContact N-OD1 3.12Å; V59-R141 HydrophobicContact CG2-CG 4.25Å; V59-R141 PolarHBondContact O-NH1 3.5Å; V59-Y142 HydrophobicContact CG2-CE1 3.65Å
60L98.9Very high98.8Very high0 Ų027.2 Ų27.20%012%0.124CC..SBendtrans-101.9129.5-179.9-57.6177.4000110.6D27 S58 R62 A63 I64 N88D27-L60 WeakPolarHBondContact OD1-CA 3.41Å; S58-L60 VanDerWaalsContact C-N 3.3Å; S58-L60 PolarHBondContact OG-N 2.84Å; S58-L60 VanDerWaalsContact OG-N 3.08Å; L60-R62 VanDerWaalsContact C-N 3.26Å; L60-R62 PolarHBondContact O-N 2.82Å; L60-R62 VanDerWaalsContact O-N 3.1Å; L60-A63 PolarHBondContact O-N 2.99Å; L60-I64 PolarHBondContact O-N 3.38Å; L60-N88 HydrophobicContact CD1-CB 4.19Å
61K98.8Very high98.9Very high75 Ų7526.5 Ų26.533%0.32612%0.121SC..Hα-helixtrans-57.3-35.4-166.773.8-177.167.4169.90113.5D27 E29 A63 I64 R65D27-K61 WeakPolarHBondContact O-CD 3.49Å; D27-K61 WeakPolarHBondContact O-CE 3.38Å; D27-K61 PolarHBondContact O-NZ 3.09Å; D27-K61 WeakPolarHBondContact OD1-CG 3.23Å; D27-K61 PolarHBondContact OD1-N 2.71Å; D27-K61 WeakPolarHBondContact OD2-CE 3.44Å; D27-K61 IonicContact OD2-NZ 2.91Å; E29-K61 HydrophobicContact CB-CD 4.32Å; E29-K61 VanDerWaalsContact OE2-CD 3.28Å; E29-K61 WeakPolarHBondContact OE2-CD 3.21Å; K61-A63 VanDerWaalsContact C-N 3.31Å; K61-A63 PolarHBondContact O-N 2.7Å; K61-I64 PolarHBondContact O-N 2.86Å; K61-R65 WeakPolarHBondContact O-CB 3.23Å; K61-R65 WeakPolarHBondContact O-CG 3.37Å; K61-R65 PolarHBondContact O-N 3.1Å
62R98.8Very high98.9Very high3 Ų326.5 Ų26.51%0.01112%0.124CC..Hα-helixtrans-60.8-36.4178.660.3-170.3-177.8-91.52.4114H11 C23 G24 F26 L30 L60 T66 H186H11-R62 WeakPolarHBondContact CE1-CD 3.39Å; H11-R62 PolarHBondContact NE2-NE 3.29Å; C23-R62 PolarHBondContact SG-NH1 3.23Å; G24-R62 PolarHBondContact O-NH2 3.1Å; F26-R62 PolarHBondContact O-NH1 3.35Å; L30-R62 HydrophobicContact CD2-CB 3.88Å; L30-R62 HydrophobicContact CG-CB 4.09Å; L60-R62 VanDerWaalsContact C-N 3.26Å; L60-R62 PolarHBondContact O-N 2.82Å; L60-R62 VanDerWaalsContact O-N 3.1Å; R62-T66 WeakPolarHBondContact O-CB 3.3Å; R62-T66 PolarHBondContact O-N 3.09Å; R62-T66 VanDerWaalsContact O-N 3.16Å; R62-T66 PolarHBondContact O-OG1 3.21Å; R62-H186 PolarHBondContact NE-CE1 2.96Å; R62-H186 PolarHBondContact NE-ND1 2.89Å
63A98.9Very high98.9Very high0 Ų027.8 Ų27.80%014%0.138CC..Hα-helixtrans-76.4-41.4175.100000111T57 S58 L60 K61 R65 T66 L67T57-A63 WeakPolarHBondContact OG1-CB 3.38Å; S58-A63 WeakPolarHBondContact OG-CB 3.06Å; L60-A63 PolarHBondContact O-N 2.99Å; K61-A63 VanDerWaalsContact C-N 3.31Å; K61-A63 PolarHBondContact O-N 2.7Å; A63-R65 PolarHBondContact O-N 3.08Å; A63-T66 PolarHBondContact O-N 3.04Å; A63-L67 PolarHBondContact O-N 3.26Å
64I98.9Very high98.9Very high22 Ų2226.2 Ų26.211%0.11313%0.13CC..Hα-helixtrans-59.8-46.3176-61.3168.1000111T57 L60 K61 L67 W68T57-I64 HydrophobicContact CG2-CG1 3.78Å; L60-I64 PolarHBondContact O-N 3.38Å; K61-I64 PolarHBondContact O-N 2.86Å; I64-L67 WeakPolarHBondContact O-CB 3.27Å; I64-L67 PolarHBondContact O-N 3.09Å; I64-W68 HydrophobicContact CG2-CD2 3.98Å; I64-W68 HydrophobicContact CG2-CE3 4.45Å; I64-W68 HydrophobicContact CG2-CH2 4.24Å; I64-W68 HydrophobicContact CG2-CZ2 3.75Å; I64-W68 PolarHBondContact O-N 3.3Å
65R98.9Very high98.9Very high113 Ų11332.1 Ų32.143%0.42616%0.162SC..Hα-helixtrans-68.9-34.5178.4-72-162.5-163.8-89.29.4112.9E29 L30 K61 A63 L67 W68 A69E29-R65 WeakPolarHBondContact OE1-CD 3.17Å; E29-R65 IonicContact OE1-NE 2.79Å; E29-R65 PolarHBondContact OE1-NE 3.38Å; E29-R65 IonicContact OE2-CZ 2.62Å; E29-R65 VanDerWaalsContact OE2-CZ 3.23Å; E29-R65 IonicContact OE2-NE 3.14Å; E29-R65 PolarHBondContact OE2-NE 2.84Å; E29-R65 IonicContact OE2-NH2 2.72Å; E29-R65 PolarHBondContact OE2-NH2 2.87Å; L30-R65 HydrophobicContact CD1-CB 3.82Å; K61-R65 WeakPolarHBondContact O-CB 3.23Å; K61-R65 WeakPolarHBondContact O-CG 3.37Å; K61-R65 PolarHBondContact O-N 3.1Å; A63-R65 PolarHBondContact O-N 3.08Å; R65-L67 VanDerWaalsContact C-N 3.32Å; R65-W68 HydrophobicContact CG-CE3 4.42Å; R65-W68 PolarHBondContact O-N 3.26Å; R65-A69 WeakPolarHBondContact O-CB 3.4Å; R65-A69 PolarHBondContact O-N 2.91Å
66T98.9Very high98.8Very high0 Ų032.8 Ų32.80%017%0.165CC..Hα-helixtrans-60.9-46.5170.8-64.30000110.1V9 H11 G12 A38 R62 A63 W68 A69 I70V9-T66 HydrophobicContact CG1-CG2 4.06Å; H11-T66 WeakPolarHBondContact CA-OG1 3.37Å; H11-T66 VanDerWaalsContact CB-OG1 3.31Å; H11-T66 WeakPolarHBondContact CB-OG1 3.38Å; G12-T66 PolarHBondContact N-OG1 3.3Å; A38-T66 HydrophobicContact CB-CG2 3.99Å; R62-T66 WeakPolarHBondContact O-CB 3.3Å; R62-T66 PolarHBondContact O-N 3.09Å; R62-T66 VanDerWaalsContact O-N 3.16Å; R62-T66 PolarHBondContact O-OG1 3.21Å; A63-T66 PolarHBondContact O-N 3.04Å; T66-W68 PolarHBondContact O-N 2.88Å; T66-A69 PolarHBondContact O-N 3.19Å; T66-I70 HydrophobicContact CG2-CD1 3.99Å; T66-I70 WeakPolarHBondContact O-CG1 3.24Å; T66-I70 PolarHBondContact O-N 2.85Å; T66-I70 VanDerWaalsContact O-N 3.09Å
67L98.9Very high98.8Very high0 Ų038.6 Ų38.60%019%0.194CC..Hα-helixtrans-59.3-47.5175.6-179.457.5000111.6C55 T57 A63 I64 R65 A69 I70 L71 V81 L182 A184C55-L67 HydrophobicContact CB-CD1 3.84Å; C55-L67 HydrophobicContact CB-CD2 3.8Å; C55-L67 HydrophobicContact CB-CG 4.4Å; T57-L67 HydrophobicContact CG2-CD2 3.94Å; A63-L67 PolarHBondContact O-N 3.26Å; I64-L67 WeakPolarHBondContact O-CB 3.27Å; I64-L67 PolarHBondContact O-N 3.09Å; R65-L67 VanDerWaalsContact C-N 3.32Å; L67-A69 PolarHBondContact O-N 3.47Å; L67-I70 WeakPolarHBondContact O-CB 3.43Å; L67-I70 PolarHBondContact O-N 2.94Å; L67-I70 VanDerWaalsContact O-N 3.1Å; L67-L71 HydrophobicContact CD1-CD1 4.25Å; L67-L71 HydrophobicContact CD1-CD2 4.3Å; L67-L71 HydrophobicContact CD1-CG 4.03Å; L67-L71 HydrophobicContact CG-CD1 4.1Å; L67-L71 HydrophobicContact CG-CG 4.26Å; L67-L71 WeakPolarHBondContact O-CG 3.36Å; L67-L71 PolarHBondContact O-N 3.08Å; L67-V81 HydrophobicContact CD2-CB 4.44Å; L67-V81 HydrophobicContact CD2-CG1 3.5Å; L67-V81 HydrophobicContact CD2-CG2 4.08Å; L67-L182 HydrophobicContact CD1-CD2 3.47Å; L67-L182 VanDerWaalsContact CD1-CD2 3.47Å; L67-L182 HydrophobicContact CD1-CG 4.04Å; L67-A184 HydrophobicContact CB-CB 3.72Å; L67-A184 HydrophobicContact CD1-CB 4.31Å; L67-A184 HydrophobicContact CG-CB 4.47Å
68W98.9Very high98.8Very high119 Ų11947.9 Ų47.945%0.45123%0.229SC..Hα-helixtrans-59.6-43.5178.9-70.6-13.1000112.8I64 R65 T66 I70 L71 D72I64-W68 HydrophobicContact CG2-CD2 3.98Å; I64-W68 HydrophobicContact CG2-CE3 4.45Å; I64-W68 HydrophobicContact CG2-CH2 4.24Å; I64-W68 HydrophobicContact CG2-CZ2 3.75Å; I64-W68 PolarHBondContact O-N 3.3Å; R65-W68 HydrophobicContact CG-CE3 4.42Å; R65-W68 PolarHBondContact O-N 3.26Å; T66-W68 PolarHBondContact O-N 2.88Å; W68-I70 VanDerWaalsContact C-N 3.26Å; W68-I70 PolarHBondContact O-N 3.37Å; W68-L71 PolarHBondContact O-N 2.62Å; W68-D72 VanDerWaalsContact O-CB 3.27Å; W68-D72 WeakPolarHBondContact O-CB 3.39Å; W68-D72 PolarHBondContact O-N 3.06Å
69A98.9Very high98.8Very high23 Ų2348.2 Ų48.219%0.1923%0.231CC..Hα-helixtrans-61.4-35.6175.300000112.3A38 A42 R65 T66 L67 G73A38-A69 HydrophobicContact CB-CB 3.84Å; A42-A69 WeakPolarHBondContact CB-O 3.43Å; R65-A69 WeakPolarHBondContact O-CB 3.4Å; R65-A69 PolarHBondContact O-N 2.91Å; T66-A69 PolarHBondContact O-N 3.19Å; L67-A69 PolarHBondContact O-N 3.47Å; A69-G73 PolarHBondContact O-N 3Å
70I98.9Very high98.8Very high0 Ų050.3 Ų50.30%025%0.245CC..Hα-helixtrans-67.6-48.1174.5-67.5164.8000111.2V9 A42 I45 T66 L67 W68 G73 T74 L182V9-I70 HydrophobicContact CB-CD1 4.25Å; V9-I70 HydrophobicContact CG1-CD1 4.19Å; V9-I70 HydrophobicContact CG2-CD1 3.88Å; A42-I70 HydrophobicContact CB-CB 4.45Å; A42-I70 HydrophobicContact CB-CG1 4.3Å; I45-I70 HydrophobicContact CD1-CD1 4.37Å; I45-I70 HydrophobicContact CD1-CG1 4.43Å; I45-I70 HydrophobicContact CD1-CG2 3.59Å; T66-I70 HydrophobicContact CG2-CD1 3.99Å; T66-I70 WeakPolarHBondContact O-CG1 3.24Å; T66-I70 PolarHBondContact O-N 2.85Å; T66-I70 VanDerWaalsContact O-N 3.09Å; L67-I70 WeakPolarHBondContact O-CB 3.43Å; L67-I70 PolarHBondContact O-N 2.94Å; L67-I70 VanDerWaalsContact O-N 3.1Å; W68-I70 VanDerWaalsContact C-N 3.26Å; W68-I70 PolarHBondContact O-N 3.37Å; I70-G73 PolarHBondContact O-N 2.9Å; I70-T74 HydrophobicContact CG2-CG2 4.48Å; I70-T74 WeakPolarHBondContact O-CB 3.34Å; I70-T74 VanDerWaalsContact O-CG2 3.27Å; I70-T74 WeakPolarHBondContact O-CG2 3.15Å; I70-T74 PolarHBondContact O-N 3.22Å; I70-T74 PolarHBondContact O-OG1 3.14Å; I70-L182 HydrophobicContact CG2-CD2 3.71Å
71L98.9Very high98.8Very high4 Ų452 Ų522%0.02126%0.255CS..Hα-helixtrans-64.8-41.8-179.2-64.7-176.8000112L67 W68 T74 D75 Q76 M77 L79 V81 L182L67-L71 HydrophobicContact CD1-CD1 4.25Å; L67-L71 HydrophobicContact CD1-CD2 4.3Å; L67-L71 HydrophobicContact CD1-CG 4.03Å; L67-L71 HydrophobicContact CG-CD1 4.1Å; L67-L71 HydrophobicContact CG-CG 4.26Å; L67-L71 WeakPolarHBondContact O-CG 3.36Å; L67-L71 PolarHBondContact O-N 3.08Å; W68-L71 PolarHBondContact O-N 2.62Å; L71-T74 PolarHBondContact O-N 2.72Å; L71-T74 PolarHBondContact O-OG1 2.92Å; L71-D75 PolarHBondContact O-N 3.23Å; L71-D75 VanDerWaalsContact O-N 3.1Å; L71-Q76 HydrophobicContact CD2-CB 4.12Å; L71-Q76 PolarHBondContact O-N 2.99Å; L71-M77 HydrophobicContact CB-CG 4.29Å; L71-L79 HydrophobicContact CD2-CD1 4.06Å; L71-V81 HydrophobicContact CD1-CG2 3.91Å; L71-L182 HydrophobicContact CD2-CD2 4.48Å
72D98.8Very high98.8Very high108 Ų10851 Ų5158%0.57826%0.255SS*.Hα-helixtrans-62.7-53174.3-177.222.7000110.9W68 T74 D75 M77W68-D72 VanDerWaalsContact O-CB 3.27Å; W68-D72 WeakPolarHBondContact O-CB 3.39Å; W68-D72 PolarHBondContact O-N 3.06Å; D72-T74 PolarHBondContact O-N 3.36Å; D72-D75 PolarHBondContact O-N 2.79Å; D72-D75 VanDerWaalsContact O-N 3.11Å; D72-M77 HydrophobicContact CB-CG 4.27Å; D72-M77 HydrophobicContact CB-SD 4.06Å
73G98.6Very high98.8Very high30 Ų3055.8 Ų55.831%0.30927%0.273SS..Hα-helixtrans-63.7-17.2-179.100000114.9K46 A69 I70K46-G73 WeakPolarHBondContact CD-O 3.4Å; A69-G73 PolarHBondContact O-N 3Å; I70-G73 PolarHBondContact O-N 2.9Å
74T98.7Very high98.8Very high16 Ų1656.6 Ų56.610%0.09828%0.278CS..THydrogen-bonded Turntrans-110.54.1179.3610000113.8A42 I45 K46 I70 L71 D72 Q76A42-T74 WeakPolarHBondContact O-CG2 3.5Å; I45-T74 HydrophobicContact CB-CG2 4.03Å; I45-T74 HydrophobicContact CG2-CG2 3.6Å; K46-T74 HydrophobicContact CB-CG2 4.14Å; I70-T74 HydrophobicContact CG2-CG2 4.48Å; I70-T74 WeakPolarHBondContact O-CB 3.34Å; I70-T74 VanDerWaalsContact O-CG2 3.27Å; I70-T74 WeakPolarHBondContact O-CG2 3.15Å; I70-T74 PolarHBondContact O-N 3.22Å; I70-T74 PolarHBondContact O-OG1 3.14Å; L71-T74 PolarHBondContact O-N 2.72Å; L71-T74 PolarHBondContact O-OG1 2.92Å; D72-T74 PolarHBondContact O-N 3.36Å; T74-Q76 VanDerWaalsContact CB-NE2 3.34Å; T74-Q76 PolarHBondContact OG1-NE2 3.04Å
75D98.8Very high98.8Very high136 Ų13656.8 Ų56.873%0.72728%0.277SS*.THydrogen-bonded Turntrans58.443.5-177.5-163.526.4000114.2L71 D72L71-D75 PolarHBondContact O-N 3.23Å; L71-D75 VanDerWaalsContact O-N 3.1Å; D72-D75 PolarHBondContact O-N 2.79Å; D72-D75 VanDerWaalsContact O-N 3.11Å
76Q98.8Very high98.8Very high14 Ų1453.9 Ų53.97%0.06527%0.266CS..  trans-128.125.9-175.3-70.5179.898.800112.3M50 E51 L71 T74 W78 L79M50-Q76 PolarHBondContact O-NE2 3.01Å; E51-Q76 VanDerWaalsContact CA-OE1 3.28Å; L71-Q76 HydrophobicContact CD2-CB 4.12Å; L71-Q76 PolarHBondContact O-N 2.99Å; T74-Q76 VanDerWaalsContact CB-NE2 3.34Å; T74-Q76 PolarHBondContact OG1-NE2 3.04Å; Q76-W78 PolarHBondContact O-N 3.24Å; Q76-W78 VanDerWaalsContact O-N 3.12Å; Q76-L79 HydrophobicContact CB-CD1 3.73Å; Q76-L79 HydrophobicContact CB-CG 4.04Å; Q76-L79 HydrophobicContact CG-CD1 4.31Å; Q76-L79 WeakPolarHBondContact O-CB 3.48Å; Q76-L79 WeakPolarHBondContact O-CG 3.22Å; Q76-L79 PolarHBondContact O-N 3.32Å; Q76-L79 VanDerWaalsContact O-N 3.12Å
77M98.8Very high98.8Very high125 Ų12554 Ų5462%0.61627%0.267SS*.THydrogen-bonded Turntrans-61.4-21.3-178.2-68.4-170.373.600114.4L71 D72 L79L71-M77 HydrophobicContact CB-CG 4.29Å; D72-M77 HydrophobicContact CB-CG 4.27Å; D72-M77 HydrophobicContact CB-SD 4.06Å; M77-L79 PolarHBondContact O-N 3.48Å
78W98.8Very high98.8Very high195 Ų19554 Ų5474%0.73927%0.267SS*.THydrogen-bonded Turntrans-75.8-9.9178.960.4-92.4000113.5Q76Q76-W78 PolarHBondContact O-N 3.24Å; Q76-W78 VanDerWaalsContact O-N 3.12Å
79L98.8Very high98.8Very high7 Ų749.1 Ų49.14%0.03725%0.249CC..SBendtrans-64.3145-177.8-71.1-178.6000112.5F52 L71 Q76 M77 V81F52-L79 HydrophobicContact CB-CD1 3.63Å; F52-L79 WeakPolarHBondContact O-CD1 3.31Å; F52-L79 WeakPolarHBondContact O-CD2 3.32Å; L71-L79 HydrophobicContact CD2-CD1 4.06Å; Q76-L79 HydrophobicContact CB-CD1 3.73Å; Q76-L79 HydrophobicContact CB-CG 4.04Å; Q76-L79 HydrophobicContact CG-CD1 4.31Å; Q76-L79 WeakPolarHBondContact O-CB 3.48Å; Q76-L79 WeakPolarHBondContact O-CG 3.22Å; Q76-L79 PolarHBondContact O-N 3.32Å; Q76-L79 VanDerWaalsContact O-N 3.12Å; M77-L79 PolarHBondContact O-N 3.48Å; L79-V81 PolarHBondContact O-N 2.74Å
80P98.8Very high98.7Very high67 Ų6748.1 Ų48.144%0.43524%0.24SC..  trans-65.3132.3175.126.5-32.4000110.9D53 I54 C55D53-P80 WeakPolarHBondContact O-CD 3.48Å; D53-P80 WeakPolarHBondContact O-CG 3.38Å; I54-P80 HydrophobicContact CB-CG 4.32Å; I54-P80 HydrophobicContact CG1-CG 4.24Å; C55-P80 PolarHBondContact N-O 2.78Å
81V98.9Very high98.6Very high34 Ų3448.1 Ų48.121%0.20624%0.24CC..EExtended strand (participates in β ladder)trans-119.1116.7178.9-178.30000110.9C55 T57 L67 L71 L79 R83C55-V81 HydrophobicContact CB-CG2 4.21Å; C55-V81 WeakPolarHBondContact O-CA 3.44Å; T57-V81 HydrophobicContact CG2-CG1 4.12Å; L67-V81 HydrophobicContact CD2-CB 4.44Å; L67-V81 HydrophobicContact CD2-CG1 3.5Å; L67-V81 HydrophobicContact CD2-CG2 4.08Å; L71-V81 HydrophobicContact CD1-CG2 3.91Å; L79-V81 PolarHBondContact O-N 2.74Å; V81-R83 HydrophobicContact CG1-CG 4.38Å; V81-R83 PolarHBondContact O-NH1 2.75Å
82V98.9Very high98.6Very high54 Ų5449.1 Ų49.133%0.32724%0.244SC..EExtended strand (participates in β ladder)trans-98.4130.8173.9-177.80000109.8I54 C55 Y56 T57 F166I54-V82 HydrophobicContact CD1-CG2 4.26Å; C55-V82 PolarHBondContact O-N 3.47Å; Y56-V82 WeakPolarHBondContact CA-O 3.31Å; Y56-V82 HydrophobicContact CD1-CB 3.64Å; Y56-V82 HydrophobicContact CD1-CG1 4.05Å; Y56-V82 HydrophobicContact CD1-CG2 4.38Å; Y56-V82 HydrophobicContact CE1-CB 3.73Å; Y56-V82 HydrophobicContact CE1-CG1 4.05Å; Y56-V82 HydrophobicContact CE1-CG2 4Å; T57-V82 PolarHBondContact N-O 3.24Å; V82-F166 HydrophobicContact CG1-CE2 4.47Å; V82-F166 HydrophobicContact CG1-CZ 4.03Å
83R98.9Very high98.5Very high104 Ų10444 Ų4439%0.39222%0.217SC..EExtended strand (participates in β ladder)trans-114.4135.3-179.6-68.3168.5-177.278.4-1.1109.7T57 V59 V81T57-R83 HydrophobicContact CG2-CG 3.67Å; T57-R83 WeakPolarHBondContact O-CA 3.34Å; V59-R83 HydrophobicContact CG1-CB 4.33Å; V81-R83 HydrophobicContact CG1-CG 4.38Å; V81-R83 PolarHBondContact O-NH1 2.75Å
84T98.8Very high98.4Very high17 Ų1743.6 Ų43.610%0.10421%0.212CC..  trans-147.9142.4178.5-178.60000112.8T57 S58 V59 R86 L87 F166T57-T84 PolarHBondContact O-N 2.87Å; S58-T84 VanDerWaalsContact CA-O 3.3Å; S58-T84 WeakPolarHBondContact CA-O 3.41Å; V59-T84 PolarHBondContact N-O 3.43Å; T84-R86 HydrophobicContact CG2-CB 4.24Å; T84-R86 PolarHBondContact O-N 2.93Å; T84-R86 PolarHBondContact OG1-N 3.38Å; T84-L87 HydrophobicContact CG2-CB 3.95Å; T84-L87 HydrophobicContact CG2-CD1 3.86Å; T84-L87 HydrophobicContact CG2-CG 3.63Å; T84-L87 PolarHBondContact O-N 3.38Å; T84-F166 HydrophobicContact CG2-CD1 3.69Å; T84-F166 HydrophobicContact CG2-CD2 3.9Å; T84-F166 HydrophobicContact CG2-CE1 3.43Å; T84-F166 VanDerWaalsContact CG2-CE1 3.43Å; T84-F166 HydrophobicContact CG2-CE2 3.64Å; T84-F166 HydrophobicContact CG2-CG 3.92Å; T84-F166 HydrophobicContact CG2-CZ 3.4Å; T84-F166 VanDerWaalsContact CG2-CZ 3.4Å
85W98.8Very high98.2Very high27 Ų2743.1 Ų43.110%0.10221%0.209CC..G310 helixtrans-64.6-23.9172.276.4-91.9000111.8W25 V59 L87 N88 Y142 L145 E149 R162W25-W85 HydrophobicContact CH2-CD2 4.45Å; W25-W85 AromaticContact CH2-CE3 3.58Å; W25-W85 HydrophobicContact CH2-CE3 3.58Å; W25-W85 HydrophobicContact CH2-CZ3 4.08Å; W25-W85 AromaticContact CZ2-CE3 3.85Å; W25-W85 HydrophobicContact CZ2-CE3 3.85Å; W25-W85 HydrophobicContact CZ2-CZ3 4.22Å; V59-W85 HydrophobicContact CG2-CB 4.17Å; W85-L87 PolarHBondContact O-N 3.49Å; W85-L87 VanDerWaalsContact O-N 3.09Å; W85-N88 WeakPolarHBondContact O-CB 3.49Å; W85-N88 VanDerWaalsContact O-CG 3.3Å; W85-N88 PolarHBondContact O-N 3.1Å; W85-Y142 HydrophobicContact CB-CD1 4.3Å; W85-Y142 HydrophobicContact CB-CE1 4.1Å; W85-L145 HydrophobicContact CD2-CD2 3.89Å; W85-L145 HydrophobicContact CD2-CG 4.45Å; W85-L145 HydrophobicContact CE3-CD2 4.42Å; W85-L145 HydrophobicContact CG-CD1 4.09Å; W85-L145 HydrophobicContact CG-CD2 4.12Å; W85-L145 HydrophobicContact CG-CG 4.43Å; W85-L145 HydrophobicContact CZ2-CD2 4.14Å; W85-L145 HydrophobicContact CZ2-CG 4.45Å; W85-E149 HydrophobicContact CH2-CB 4.47Å; W85-E149 VanDerWaalsContact CH2-O 3.24Å; W85-E149 WeakPolarHBondContact CH2-O 3.4Å; W85-E149 HydrophobicContact CZ2-CB 4.1Å; W85-R162 HydrophobicContact CH2-CB 3.8Å; W85-R162 HydrophobicContact CH2-CG 4.15Å; W85-R162 HydrophobicContact CZ3-CB 4.04Å; W85-R162 HydrophobicContact CZ3-CG 3.86Å
86R98.6Very high98.2Very high52 Ų5236.7 Ų36.720%0.19618%0.175CC..G310 helixtrans-64.9-13.1177.7-65.6-177.7178.2-78.4-3.4113.1T84 E149 R162 A163 F166T84-R86 HydrophobicContact CG2-CB 4.24Å; T84-R86 PolarHBondContact O-N 2.93Å; T84-R86 PolarHBondContact OG1-N 3.38Å; R86-E149 IonicContact NH2-OE1 2.95Å; R86-E149 PolarHBondContact NH2-OE1 2.85Å; R86-E149 VanDerWaalsContact NH2-OE1 3.09Å; R86-R162 VanDerWaalsContact C-NH1 3.34Å; R86-R162 WeakPolarHBondContact CB-O 3.13Å; R86-R162 WeakPolarHBondContact CD-O 3.46Å; R86-R162 WeakPolarHBondContact CG-O 3.44Å; R86-R162 PolarHBondContact NH1-O 2.87Å; R86-R162 PolarHBondContact O-NH1 2.89Å; R86-A163 WeakPolarHBondContact O-CA 3.22Å; R86-A163 WeakPolarHBondContact O-CB 3.47Å; R86-F166 HydrophobicContact CB-CB 3.84Å; R86-F166 HydrophobicContact CB-CG 4.29Å; R86-F166 HydrophobicContact CG-CB 4.42Å
87L98.8Very high98.1Very high2 Ų236.2 Ų36.21%0.0117%0.174CC..G310 helixtrans-102.34.1171-70.5179.1000113.5S58 T84 W85 F166 I183 H186 S189 I193S58-L87 VanDerWaalsContact CB-C 3.48Å; S58-L87 VanDerWaalsContact CB-O 3.3Å; S58-L87 WeakPolarHBondContact CB-O 3.31Å; T84-L87 HydrophobicContact CG2-CB 3.95Å; T84-L87 HydrophobicContact CG2-CD1 3.86Å; T84-L87 HydrophobicContact CG2-CG 3.63Å; T84-L87 PolarHBondContact O-N 3.38Å; W85-L87 PolarHBondContact O-N 3.49Å; W85-L87 VanDerWaalsContact O-N 3.09Å; L87-F166 HydrophobicContact CD1-CD1 4.3Å; L87-F166 HydrophobicContact CD1-CE1 3.91Å; L87-F166 HydrophobicContact CD2-CD1 4.49Å; L87-F166 HydrophobicContact CG-CD1 4.14Å; L87-F166 HydrophobicContact CG-CE1 4.23Å; L87-I183 HydrophobicContact CD1-CG2 4.13Å; L87-H186 PolarHBondContact O-CD2 3.19Å; L87-H186 VanDerWaalsContact O-CD2 3.28Å; L87-S189 PolarHBondContact O-OG 3.26Å; L87-I193 HydrophobicContact CD2-CD1 4.15Å
88N98.8Very high97.9Very high0 Ų033.9 Ų33.90%016%0.163CC..SBendtrans-58.5159.1174.5-76.71.4000111.8W25 S58 V59 L60 W85 Y142 R162 S189W25-N88 HydrophobicContact CZ2-CB 4.23Å; S58-N88 WeakPolarHBondContact CB-OD1 3.21Å; V59-N88 VanDerWaalsContact CG2-OD1 3.26Å; V59-N88 WeakPolarHBondContact CG2-OD1 3.4Å; V59-N88 PolarHBondContact N-OD1 2.97Å; V59-N88 VanDerWaalsContact N-OD1 3.12Å; L60-N88 HydrophobicContact CD1-CB 4.19Å; W85-N88 WeakPolarHBondContact O-CB 3.49Å; W85-N88 VanDerWaalsContact O-CG 3.3Å; W85-N88 PolarHBondContact O-N 3.1Å; N88-Y142 PolarHBondContact ND2-OH 3.16Å; N88-R162 VanDerWaalsContact O-CZ 3.28Å; N88-R162 PolarHBondContact O-NH1 3.21Å; N88-R162 PolarHBondContact O-NH2 3.07Å; N88-S189 WeakPolarHBondContact O-CB 3.41Å
89E98.1Very high97.6Very high17 Ų1726 Ų268%0.07914%0.136CC..PPolyproline II helixtrans-58.3162.5167.9-172.354.2-74.400111W25 H91 Y92 R162 H186 G187 N188W25-E89 PolarHBondContact NE1-O 2.95Å; E89-H91 PolarHBondContact O-N 3.04Å; E89-Y92 HydrophobicContact CG-CE2 4.46Å; E89-R162 PolarHBondContact O-NH2 2.95Å; E89-R162 VanDerWaalsContact O-NH2 3.09Å; E89-H186 HydrophobicContact CB-CB 3.69Å; E89-H186 HydrophobicContact CG-CB 4.11Å; E89-H186 PolarHBondContact N-CD2 3.36Å; E89-H186 WeakPolarHBondContact OE2-CB 3.31Å; E89-G187 PolarHBondContact OE2-N 3.04Å; E89-N188 WeakPolarHBondContact OE1-CB 3.42Å; E89-N188 PolarHBondContact OE1-N 3.17Å; E89-N188 PolarHBondContact OE1-ND2 3.24Å
90R97.2Very high97.1Very high1 Ų127.5 Ų27.50%0.00414%0.142CC..PPolyproline II helixtrans-53.1130.4169178.7177.9178.7178.80.8110.9G24 Y92 W115 I121 E154 N188G24-R90 VanDerWaalsContact CA-O 3.28Å; G24-R90 WeakPolarHBondContact CA-O 3.4Å; R90-Y92 HydrophobicContact CG-CE1 4.47Å; R90-Y92 PolarHBondContact O-N 3.12Å; R90-W115 VanDerWaalsContact CZ-O 3.25Å; R90-W115 PolarHBondContact NH1-O 3.45Å; R90-W115 PolarHBondContact NH2-O 3.21Å; R90-I121 PolarHBondContact NH2-O 3.21Å; R90-E154 HydrophobicContact CG-CB 4.09Å; R90-E154 WeakPolarHBondContact CG-O 3.41Å; R90-E154 PolarHBondContact NE-O 2.6Å; R90-E154 PolarHBondContact NH2-O 2.89Å; R90-N188 HydrophobicContact CB-CB 3.86Å
91H98Very high96.6Very high0 Ų027.1 Ų27.10%015%0.145CC..  trans-73.2108174-159.2-49.5000110.7W25 E89 G93 P151 C153 E154W25-H91 AromaticContact CD1-CD2 3.91Å; W25-H91 AromaticContact CD1-CG 3.93Å; W25-H91 HydrophobicContact CD2-CB 4.38Å; W25-H91 AromaticContact CD2-CD2 3.38Å; W25-H91 AromaticContact CE2-CD2 3.78Å; W25-H91 AromaticContact CE3-CD2 3.76Å; W25-H91 HydrophobicContact CG-CB 4.18Å; W25-H91 AromaticContact CG-CD2 3.48Å; W25-H91 VanDerWaalsContact CG-CD2 3.48Å; W25-H91 AromaticContact CG-CG 3.9Å; E89-H91 PolarHBondContact O-N 3.04Å; H91-G93 PolarHBondContact ND1-N 3.03Å; H91-G93 VanDerWaalsContact ND1-N 3.14Å; H91-G93 PolarHBondContact O-N 2.74Å; H91-P151 HydrophobicContact CB-CG 4.27Å; H91-P151 PolarHBondContact CD2-O 3.23Å; H91-P151 VanDerWaalsContact CD2-O 3.23Å; H91-P151 PolarHBondContact NE2-O 3.33Å; H91-C153 CarbonylContact O-C 3.53Å; H91-C153 WeakPolarHBondContact O-CA 3.32Å; H91-E154 HydrophobicContact CB-CB 4.22Å; H91-E154 HydrophobicContact CB-CG 3.85Å; H91-E154 PolarHBondContact N-OE2 3.03Å; H91-E154 PolarHBondContact O-N 3Å
92Y97.1Very high96.1Very high26 Ų2631.8 Ų31.810%0.10216%0.164CC..  trans-76.212.4-178.3-73.8-63.1000115.1F22 E89 R90 G94 L95 N188F22-Y92 HydrophobicContact CB-CD2 4.24Å; F22-Y92 HydrophobicContact CB-CG 4.26Å; F22-Y92 AromaticContact CD1-CD1 3.74Å; F22-Y92 HydrophobicContact CD1-CD1 3.74Å; F22-Y92 HydrophobicContact CD1-CD2 4.09Å; F22-Y92 AromaticContact CD1-CE1 3.97Å; F22-Y92 HydrophobicContact CD1-CE1 3.97Å; F22-Y92 HydrophobicContact CD1-CE2 4.3Å; F22-Y92 AromaticContact CD1-CG 3.82Å; F22-Y92 HydrophobicContact CD1-CG 3.82Å; F22-Y92 HydrophobicContact CE1-CD1 4.18Å; F22-Y92 HydrophobicContact CE1-CE1 4.21Å; F22-Y92 HydrophobicContact CG-CG 4.47Å; E89-Y92 HydrophobicContact CG-CE2 4.46Å; R90-Y92 HydrophobicContact CG-CE1 4.47Å; R90-Y92 PolarHBondContact O-N 3.12Å; Y92-G94 PolarHBondContact O-N 2.71Å; Y92-L95 VanDerWaalsContact O-CB 3.31Å; Y92-L95 WeakPolarHBondContact O-CB 3.45Å; Y92-L95 PolarHBondContact O-N 2.93Å; Y92-N188 PolarHBondContact OH-ND2 2.79Å
93G97.4Very high95.6Very high0 Ų029.5 Ų29.50%015%0.15CC..G310 helixtrans40-127.3-175.200000115H91 L95 T96 P124 M126 T152H91-G93 PolarHBondContact ND1-N 3.03Å; H91-G93 VanDerWaalsContact ND1-N 3.14Å; H91-G93 PolarHBondContact O-N 2.74Å; G93-L95 PolarHBondContact O-N 3.09Å; G93-L95 VanDerWaalsContact O-N 3.16Å; G93-T96 WeakPolarHBondContact O-CB 3.26Å; G93-T96 PolarHBondContact O-N 3.27Å; G93-T96 VanDerWaalsContact O-N 3.11Å; G93-T96 PolarHBondContact O-OG1 3.08Å; G93-P124 CarbonylContact C-O 3.57Å; G93-P124 WeakPolarHBondContact CA-O 3.27Å; G93-M126 WeakPolarHBondContact O-CE 3.24Å; G93-T152 WeakPolarHBondContact CA-O 3.31Å
94G96.6Very high95.1Very high21 Ų2125.4 Ų25.422%0.21614%0.139CC..G310 helixtrans-67.9-5.1179.900000115Y92 P124Y92-G94 PolarHBondContact O-N 2.71Å; G94-P124 PolarHBondContact N-O 3.27Å
95L95.8Very high94.5Very high6 Ų629 Ų293%0.03117%0.17CC..G310 helixtrans-83-14.6171.1-54.2179.8000112.4F22 Y92 G93 G97 L98 T103 W115 P123F22-L95 HydrophobicContact CB-CB 4.4Å; F22-L95 VanDerWaalsContact CB-O 3.31Å; F22-L95 WeakPolarHBondContact CB-O 3.4Å; F22-L95 HydrophobicContact CD2-CB 4.04Å; F22-L95 HydrophobicContact CE1-CD1 4.37Å; F22-L95 HydrophobicContact CE2-CB 4.4Å; F22-L95 HydrophobicContact CE2-CD1 4.45Å; F22-L95 HydrophobicContact CG-CB 4.12Å; F22-L95 HydrophobicContact CZ-CD1 4.22Å; Y92-L95 VanDerWaalsContact O-CB 3.31Å; Y92-L95 WeakPolarHBondContact O-CB 3.45Å; Y92-L95 PolarHBondContact O-N 2.93Å; G93-L95 PolarHBondContact O-N 3.09Å; G93-L95 VanDerWaalsContact O-N 3.16Å; L95-G97 PolarHBondContact O-N 3.16Å; L95-L98 HydrophobicContact CD2-CD1 4.17Å; L95-L98 WeakPolarHBondContact O-CB 3.36Å; L95-L98 WeakPolarHBondContact O-CG 3.35Å; L95-L98 PolarHBondContact O-N 3.31Å; L95-T103 HydrophobicContact CD2-CG2 4.29Å; L95-W115 HydrophobicContact CD1-CB 3.91Å; L95-W115 HydrophobicContact CD1-CD2 4.01Å; L95-W115 HydrophobicContact CD1-CE3 3.79Å; L95-W115 HydrophobicContact CD1-CG 4.11Å; L95-W115 HydrophobicContact CD2-CE3 4.07Å; L95-W115 HydrophobicContact CD2-CZ3 4.07Å; L95-P123 HydrophobicContact CD1-CB 3.63Å; L95-P123 HydrophobicContact CG-CB 3.98Å
96T97.6Very high93.9Very high1 Ų135.9 Ų35.91%0.00620%0.201CC..THydrogen-bonded Turntrans-55.6123.6-176.6-70.90000111.7W16 F22 F26 G93 M126 H130 I136W16-T96 HydrophobicContact CH2-CG2 4.48Å; W16-T96 HydrophobicContact CZ3-CG2 4.07Å; F22-T96 WeakPolarHBondContact O-CA 3.43Å; F26-T96 HydrophobicContact CB-CG2 4.11Å; G93-T96 WeakPolarHBondContact O-CB 3.26Å; G93-T96 PolarHBondContact O-N 3.27Å; G93-T96 VanDerWaalsContact O-N 3.11Å; G93-T96 PolarHBondContact O-OG1 3.08Å; T96-M126 HydrophobicContact CG2-CE 3.97Å; T96-H130 PolarHBondContact O-CE1 3.34Å; T96-H130 PolarHBondContact O-NE2 3.38Å; T96-I136 HydrophobicContact CG2-CD1 3.94Å
97G96.4Very high93.3Very high5 Ų537.6 Ų37.65%0.05221%0.211CC..THydrogen-bonded Turntrans91.3-14.8-179.400000114.9R21 F22 L95R21-G97 WeakPolarHBondContact CD-O 3.4Å; R21-G97 PolarHBondContact NH1-O 3.48Å; F22-G97 PolarHBondContact O-N 2.93Å; L95-G97 PolarHBondContact O-N 3.16Å
98L94.9Very high92.7Very high75 Ų7539.1 Ų39.139%0.39323%0.228SC..  trans-72.3143.3174.8-56.3-176.1000110.9R21 F22 L95 T103R21-L98 CarbonylContact C-O 3.6Å; R21-L98 VanDerWaalsContact CA-O 3.26Å; R21-L98 WeakPolarHBondContact CA-O 3.3Å; F22-L98 HydrophobicContact CD2-CB 4.45Å; F22-L98 WeakPolarHBondContact CD2-O 3.41Å; F22-L98 PolarHBondContact N-O 3.47Å; L95-L98 HydrophobicContact CD2-CD1 4.17Å; L95-L98 WeakPolarHBondContact O-CB 3.36Å; L95-L98 WeakPolarHBondContact O-CG 3.35Å; L95-L98 PolarHBondContact O-N 3.31Å; L98-T103 WeakPolarHBondContact CB-OG1 3.44Å
99N93.3Very high92Very high29 Ų2944.9 Ų44.916%0.15525%0.254CS..BIsolated β-bridgetrans-72.5135.8169.9-177.8-71.9000109.7E19 A101 E102 T103E19-N99 PolarHBondContact O-ND2 2.81Å; N99-A101 PolarHBondContact O-N 3.23Å; N99-A101 WeakPolarHBondContact OD1-CA 3.49Å; N99-A101 WeakPolarHBondContact OD1-CB 3.48Å; N99-A101 PolarHBondContact OD1-N 3.09Å; N99-E102 HydrophobicContact CB-CB 4.1Å; N99-E102 HydrophobicContact CB-CG 3.92Å; N99-E102 WeakPolarHBondContact CB-OE2 3.27Å; N99-E102 PolarHBondContact OD1-N 2.82Å; N99-T103 WeakPolarHBondContact O-CB 3.44Å; N99-T103 PolarHBondContact O-N 2.82Å; N99-T103 PolarHBondContact O-OG1 3.08Å
100K88.3Confident91.5Very high40 Ų4050 Ų5017%0.17428%0.278CS..Hα-helixtrans-67-37.6-175.3-66.4174.6-168.8161.40113N20 F22 A104N20-K100 WeakPolarHBondContact O-CG 3.31Å; N20-K100 PolarHBondContact O-N 3.25Å; N20-K100 WeakPolarHBondContact OD1-CD 3.4Å; F22-K100 HydrophobicContact CD1-CG 4.37Å; F22-K100 HydrophobicContact CD2-CG 3.78Å; F22-K100 HydrophobicContact CE1-CG 4.16Å; F22-K100 HydrophobicContact CE2-CB 4.19Å; F22-K100 HydrophobicContact CE2-CG 3.54Å; F22-K100 HydrophobicContact CG-CG 4.2Å; F22-K100 HydrophobicContact CZ-CB 4.48Å; F22-K100 HydrophobicContact CZ-CG 3.75Å; K100-A104 WeakPolarHBondContact O-CB 3.38Å; K100-A104 PolarHBondContact O-N 3.16Å
101A87.2Confident91Very high59 Ų5953.3 Ų53.349%0.48829%0.294SS..Hα-helixtrans-70.8-44.3179.700000110.8N99 T103 A104 A105N99-A101 PolarHBondContact O-N 3.23Å; N99-A101 WeakPolarHBondContact OD1-CA 3.49Å; N99-A101 WeakPolarHBondContact OD1-CB 3.48Å; N99-A101 PolarHBondContact OD1-N 3.09Å; A101-T103 VanDerWaalsContact C-N 3.32Å; A101-T103 PolarHBondContact O-N 3.38Å; A101-A104 WeakPolarHBondContact O-CB 3.29Å; A101-A104 PolarHBondContact O-N 3.36Å; A101-A104 VanDerWaalsContact O-N 3.15Å; A101-A105 PolarHBondContact O-N 3.44Å
102E88.8Confident90.3Very high132 Ų13253.6 Ų53.662%0.61730%0.296SS*.Hα-helixtrans-62.5-40.5174.6-63.2171.9174.400111.7N99 A104 A105 K106N99-E102 HydrophobicContact CB-CB 4.1Å; N99-E102 HydrophobicContact CB-CG 3.92Å; N99-E102 WeakPolarHBondContact CB-OE2 3.27Å; N99-E102 PolarHBondContact OD1-N 2.82Å; E102-A104 VanDerWaalsContact C-N 3.3Å; E102-A104 PolarHBondContact O-N 2.93Å; E102-A105 PolarHBondContact O-N 2.88Å; E102-K106 WeakPolarHBondContact O-CB 3.3Å; E102-K106 PolarHBondContact O-N 2.78Å
103T89.4Confident89.6Confident6 Ų657.2 Ų57.24%0.03731%0.312CS..Hα-helixtrans-62.8-39.7175.3-53.40000110.8F22 L95 L98 N99 A101 K106 H107 V112 W115F22-T103 HydrophobicContact CE2-CG2 4.38Å; L95-T103 HydrophobicContact CD2-CG2 4.29Å; L98-T103 WeakPolarHBondContact CB-OG1 3.44Å; N99-T103 WeakPolarHBondContact O-CB 3.44Å; N99-T103 PolarHBondContact O-N 2.82Å; N99-T103 PolarHBondContact O-OG1 3.08Å; A101-T103 VanDerWaalsContact C-N 3.32Å; A101-T103 PolarHBondContact O-N 3.38Å; T103-K106 PolarHBondContact O-N 3.15Å; T103-H107 WeakPolarHBondContact O-CB 3.35Å; T103-H107 PolarHBondContact O-CD2 3.38Å; T103-H107 PolarHBondContact O-N 3.28Å; T103-V112 HydrophobicContact CG2-CG2 3.73Å; T103-W115 HydrophobicContact CG2-CZ3 4.22Å
104A88.4Confident89.1Confident18 Ų1860 Ų6015%0.14933%0.326CS..Hα-helixtrans-67.6-40.7177.100000111.9K100 A101 E102 K106 G108 E109 V112K100-A104 WeakPolarHBondContact O-CB 3.38Å; K100-A104 PolarHBondContact O-N 3.16Å; A101-A104 WeakPolarHBondContact O-CB 3.29Å; A101-A104 PolarHBondContact O-N 3.36Å; A101-A104 VanDerWaalsContact O-N 3.15Å; E102-A104 VanDerWaalsContact C-N 3.3Å; E102-A104 PolarHBondContact O-N 2.93Å; A104-K106 VanDerWaalsContact C-N 3.27Å; A104-K106 PolarHBondContact O-N 3.38Å; A104-G108 CarbonylContact O-C 3.35Å; A104-G108 WeakPolarHBondContact O-CA 3.41Å; A104-G108 PolarHBondContact O-N 3.04Å; A104-E109 HydrophobicContact CB-CG 4.26Å; A104-V112 HydrophobicContact CB-CB 4.32Å; A104-V112 HydrophobicContact CB-CG2 4.11Å
105A85.7Confident88.5Confident93 Ų9360.3 Ų60.377%0.76932%0.321SS*.Hα-helixtrans-61.9-35.5174.800000112.2A101 E102A101-A105 PolarHBondContact O-N 3.44Å; E102-A105 PolarHBondContact O-N 2.88Å
106K85.4Confident87.7Confident171 Ų17163.6 Ų63.674%0.74333%0.333SS*.Hα-helixtrans-82.4-38.6-179-174.4175.5178.8179.90114.2E102 T103 A104E102-K106 WeakPolarHBondContact O-CB 3.3Å; E102-K106 PolarHBondContact O-N 2.78Å; T103-K106 PolarHBondContact O-N 3.15Å; A104-K106 VanDerWaalsContact C-N 3.27Å; A104-K106 PolarHBondContact O-N 3.38Å
107H85.8Confident86.8Confident87 Ų8764.7 Ų64.740%0.40334%0.337SS..Hα-helixtrans-112.1-4-170.2-64.9-75.7000113.9T103 Q111 W115T103-H107 WeakPolarHBondContact O-CB 3.35Å; T103-H107 PolarHBondContact O-CD2 3.38Å; T103-H107 PolarHBondContact O-N 3.28Å; H107-Q111 VanDerWaalsContact O-CB 3.3Å; H107-Q111 WeakPolarHBondContact O-CB 3.46Å; H107-W115 HydrophobicContact CB-CH2 4.09Å; H107-W115 HydrophobicContact CB-CZ3 3.94Å; H107-W115 AromaticContact CG-CH2 3.96Å; H107-W115 AromaticContact CG-CZ3 3.99Å
108G87.3Confident86.3Confident35 Ų3565.2 Ų65.236%0.36134%0.34SS..  trans86.5144.5-173.600000112.7A104 E110 Q111 V112A104-G108 CarbonylContact O-C 3.35Å; A104-G108 WeakPolarHBondContact O-CA 3.41Å; A104-G108 PolarHBondContact O-N 3.04Å; G108-E110 PolarHBondContact O-N 3.08Å; G108-Q111 PolarHBondContact O-N 3.36Å; G108-V112 PolarHBondContact O-N 3.32Å
109E84.2Confident86.1Confident120 Ų12062.7 Ų62.756%0.56133%0.326SS*.Hα-helixtrans-62.4-41.7-178.9-68-169.8171.600112.8A104 Q111 V112 K113A104-E109 HydrophobicContact CB-CG 4.26Å; E109-Q111 VanDerWaalsContact C-N 3.34Å; E109-Q111 PolarHBondContact O-N 2.82Å; E109-V112 PolarHBondContact O-N 2.81Å; E109-K113 VanDerWaalsContact O-CB 3.28Å; E109-K113 WeakPolarHBondContact O-CB 3.49Å; E109-K113 PolarHBondContact O-N 2.84Å
110E86.8Confident86.1Confident125 Ų12566 Ų6658%0.58434%0.343SS*.Hα-helixtrans-61.2-42.2179.2-70.1-55.613000111.6G108 K113 I114G108-E110 PolarHBondContact O-N 3.08Å; E110-K113 WeakPolarHBondContact O-CB 3.22Å; E110-K113 PolarHBondContact O-N 3.05Å; E110-I114 VanDerWaalsContact O-CG1 3.29Å; E110-I114 WeakPolarHBondContact O-CG1 3.3Å; E110-I114 PolarHBondContact O-N 3.14Å
111Q87Confident86.3Confident71 Ų7167.7 Ų67.733%0.33235%0.353SS..Hα-helixtrans-66-42.1177.5-172.659.348.600111.9H107 G108 E109 K113 I114 W115H107-Q111 VanDerWaalsContact O-CB 3.3Å; H107-Q111 WeakPolarHBondContact O-CB 3.46Å; G108-Q111 PolarHBondContact O-N 3.36Å; E109-Q111 VanDerWaalsContact C-N 3.34Å; E109-Q111 PolarHBondContact O-N 2.82Å; Q111-K113 VanDerWaalsContact C-N 3.33Å; Q111-I114 WeakPolarHBondContact O-CB 3.27Å; Q111-I114 PolarHBondContact O-N 3.12Å; Q111-W115 HydrophobicContact CG-CD2 4.17Å; Q111-W115 HydrophobicContact CG-CE3 4.19Å; Q111-W115 HydrophobicContact CG-CH2 3.65Å; Q111-W115 HydrophobicContact CG-CZ2 3.62Å; Q111-W115 HydrophobicContact CG-CZ3 3.94Å; Q111-W115 PolarHBondContact O-N 3.12Å
112V83.3Confident86.6Confident6 Ų667.5 Ų67.54%0.03635%0.347CS..Hα-helixtrans-67.5-35.9176.5172.10000111.4F22 T103 A104 G108 E109 W115 R116F22-V112 HydrophobicContact CZ-CG1 4.21Å; T103-V112 HydrophobicContact CG2-CG2 3.73Å; A104-V112 HydrophobicContact CB-CB 4.32Å; A104-V112 HydrophobicContact CB-CG2 4.11Å; G108-V112 PolarHBondContact O-N 3.32Å; E109-V112 PolarHBondContact O-N 2.81Å; V112-W115 HydrophobicContact CG2-CE3 4.24Å; V112-W115 HydrophobicContact CG2-CZ3 4.35Å; V112-W115 PolarHBondContact O-N 2.75Å; V112-R116 HydrophobicContact CG1-CG 4.25Å; V112-R116 VanDerWaalsContact O-CB 3.26Å; V112-R116 WeakPolarHBondContact O-CB 3.5Å; V112-R116 WeakPolarHBondContact O-CG 3.37Å; V112-R116 PolarHBondContact O-N 2.77Å
113K82.6Confident86.9Confident101 Ų10161.4 Ų61.444%0.43932%0.319SS..Hα-helixtrans-63.2-43.9173.1-173.3-179.8178.3-174.90110.7E109 E110 Q111 R116 R117E109-K113 VanDerWaalsContact O-CB 3.28Å; E109-K113 WeakPolarHBondContact O-CB 3.49Å; E109-K113 PolarHBondContact O-N 2.84Å; E110-K113 WeakPolarHBondContact O-CB 3.22Å; E110-K113 PolarHBondContact O-N 3.05Å; Q111-K113 VanDerWaalsContact C-N 3.33Å; K113-R116 PolarHBondContact O-N 2.87Å; K113-R117 WeakPolarHBondContact O-CB 3.38Å; K113-R117 PolarHBondContact O-N 2.65Å
114I85.4Confident87.2Confident59 Ų5963.7 Ų63.730%0.30333%0.334SS..Hα-helixtrans-56.5-54.9172.3-71.2165.6000110.1E110 Q111 R116 R117 S118 I121E110-I114 VanDerWaalsContact O-CG1 3.29Å; E110-I114 WeakPolarHBondContact O-CG1 3.3Å; E110-I114 PolarHBondContact O-N 3.14Å; Q111-I114 WeakPolarHBondContact O-CB 3.27Å; Q111-I114 PolarHBondContact O-N 3.12Å; I114-R116 PolarHBondContact O-N 2.81Å; I114-R117 PolarHBondContact O-N 3.23Å; I114-S118 WeakPolarHBondContact O-CA 3.38Å; I114-S118 WeakPolarHBondContact O-CB 3.43Å; I114-S118 PolarHBondContact O-N 3.37Å; I114-I121 HydrophobicContact CG2-CB 4.01Å; I114-I121 HydrophobicContact CG2-CD1 3.67Å; I114-I121 HydrophobicContact CG2-CG1 4.43Å; I114-I121 HydrophobicContact CG2-CG2 3.88Å
115W85.1Confident87.6Confident28 Ų2866.5 Ų66.511%0.10635%0.351CS..Hα-helixtrans-62-31179.9-67.3-34.2000113.8R90 L95 T103 H107 Q111 V112 P123 P124R90-W115 VanDerWaalsContact CZ-O 3.25Å; R90-W115 PolarHBondContact NH1-O 3.45Å; R90-W115 PolarHBondContact NH2-O 3.21Å; L95-W115 HydrophobicContact CD1-CB 3.91Å; L95-W115 HydrophobicContact CD1-CD2 4.01Å; L95-W115 HydrophobicContact CD1-CE3 3.79Å; L95-W115 HydrophobicContact CD1-CG 4.11Å; L95-W115 HydrophobicContact CD2-CE3 4.07Å; L95-W115 HydrophobicContact CD2-CZ3 4.07Å; T103-W115 HydrophobicContact CG2-CZ3 4.22Å; H107-W115 HydrophobicContact CB-CH2 4.09Å; H107-W115 HydrophobicContact CB-CZ3 3.94Å; H107-W115 AromaticContact CG-CH2 3.96Å; H107-W115 AromaticContact CG-CZ3 3.99Å; Q111-W115 HydrophobicContact CG-CD2 4.17Å; Q111-W115 HydrophobicContact CG-CE3 4.19Å; Q111-W115 HydrophobicContact CG-CH2 3.65Å; Q111-W115 HydrophobicContact CG-CZ2 3.62Å; Q111-W115 HydrophobicContact CG-CZ3 3.94Å; Q111-W115 PolarHBondContact O-N 3.12Å; V112-W115 HydrophobicContact CG2-CE3 4.24Å; V112-W115 HydrophobicContact CG2-CZ3 4.35Å; V112-W115 PolarHBondContact O-N 2.75Å; W115-P123 HydrophobicContact CG-CB 4.46Å; W115-P124 HydrophobicContact CZ2-CG 4.13Å
116R79.5Confident88.2Confident74 Ų7462.2 Ų62.228%0.27932%0.315SS..Hα-helixtrans-79.6-36179.6-77.7178.566.2-154.5-3.1113.5F22 V112 K113 I114F22-R116 HydrophobicContact CE1-CG 3.63Å; F22-R116 HydrophobicContact CZ-CG 3.9Å; V112-R116 HydrophobicContact CG1-CG 4.25Å; V112-R116 VanDerWaalsContact O-CB 3.26Å; V112-R116 WeakPolarHBondContact O-CB 3.5Å; V112-R116 WeakPolarHBondContact O-CG 3.37Å; V112-R116 PolarHBondContact O-N 2.77Å; K113-R116 PolarHBondContact O-N 2.87Å; I114-R116 PolarHBondContact O-N 2.81Å
117R79Confident88.7Confident24 Ų2458.5 Ų58.59%0.09130%0.303CS..Hα-helixtrans-122.7-26.3-165.2-64-168.1170.7-153.6-7.2114.4K113 I114 F119 M206 E207K113-R117 WeakPolarHBondContact O-CB 3.38Å; K113-R117 PolarHBondContact O-N 2.65Å; I114-R117 PolarHBondContact O-N 3.23Å; R117-F119 PolarHBondContact O-N 3.49Å; R117-M206 WeakPolarHBondContact O-CG 3.38Å; R117-E207 IonicContact NH1-OE1 3.04Å; R117-E207 IonicContact NH1-OE2 3.33Å; R117-E207 PolarHBondContact NH1-OE2 3Å; R117-E207 VanDerWaalsContact NH1-OE2 3.12Å
118S85.5Confident89.3Confident16 Ų1661.1 Ų61.111%0.11232%0.316CS..  trans-52.5135.8178.3172.60000110.5I114 D120 I121I114-S118 WeakPolarHBondContact O-CA 3.38Å; I114-S118 WeakPolarHBondContact O-CB 3.43Å; I114-S118 PolarHBondContact O-N 3.37Å; S118-D120 PolarHBondContact OG-N 3.48Å; S118-D120 PolarHBondContact OG-OD1 3.39Å; S118-I121 VanDerWaalsContact OG-CB 3.3Å; S118-I121 WeakPolarHBondContact OG-CB 3.26Å; S118-I121 WeakPolarHBondContact OG-CG1 3.36Å; S118-I121 PolarHBondContact OG-N 2.79Å
119F89.5Confident89.8Confident23 Ų2369 Ų6910%0.10134%0.34CS..SBendtrans-65.1-47.2178.8-179.5-110.3000111.1R117 S155 L156 K157 I160 K195 D202 I205 M206R117-F119 PolarHBondContact O-N 3.49Å; F119-S155 WeakPolarHBondContact O-CB 3.37Å; F119-L156 HydrophobicContact CD2-CB 4.38Å; F119-L156 HydrophobicContact CD2-CD2 4.09Å; F119-L156 HydrophobicContact CD2-CG 4.2Å; F119-L156 CarbonylContact O-C 3.59Å; F119-L156 PolarHBondContact O-N 3Å; F119-L156 VanDerWaalsContact O-N 3.12Å; F119-K157 HydrophobicContact CD1-CB 4.13Å; F119-K157 HydrophobicContact CD1-CD 4.5Å; F119-K157 HydrophobicContact CE1-CB 3.77Å; F119-K157 HydrophobicContact CE1-CD 3.95Å; F119-K157 HydrophobicContact CE1-CG 3.83Å; F119-K157 HydrophobicContact CE2-CB 4.32Å; F119-K157 HydrophobicContact CZ-CB 3.87Å; F119-K157 HydrophobicContact CZ-CG 4Å; F119-K157 WeakPolarHBondContact O-CB 3.28Å; F119-K157 PolarHBondContact O-N 2.99Å; F119-I160 HydrophobicContact CE2-CD1 3.72Å; F119-I160 HydrophobicContact CZ-CD1 4.46Å; F119-K195 HydrophobicContact CE2-CD 3.94Å; F119-K195 VanDerWaalsContact CE2-CE 3.48Å; F119-D202 HydrophobicContact CB-CB 4.23Å; F119-D202 HydrophobicContact CD1-CB 3.92Å; F119-D202 VanDerWaalsContact CD1-CG 3.47Å; F119-D202 WeakPolarHBondContact CD1-OD2 3.49Å; F119-D202 HydrophobicContact CD2-CB 4.29Å; F119-D202 HydrophobicContact CE1-CB 4.36Å; F119-D202 VanDerWaalsContact CE1-CG 3.44Å; F119-D202 VanDerWaalsContact CE1-OD2 3.27Å; F119-D202 WeakPolarHBondContact CE1-OD2 3.2Å; F119-D202 HydrophobicContact CG-CB 3.88Å; F119-I205 HydrophobicContact CD2-CG2 4.13Å; F119-M206 HydrophobicContact CB-SD 4.38Å
120D93.2Very high90.4Very high97 Ų9764.6 Ų64.652%0.51932%0.319SS..SBendtrans-117.2-9.8-166.262.3-15000114.7S118 P122 K157S118-D120 PolarHBondContact OG-N 3.48Å; S118-D120 PolarHBondContact OG-OD1 3.39Å; D120-P122 VanDerWaalsContact O-CD 3.24Å; D120-P122 WeakPolarHBondContact O-CD 3.36Å; D120-K157 HydrophobicContact CB-CD 4.24Å
121I92.8Very high90.9Very high76 Ų7664 Ų6439%0.3933%0.326SS..  trans-88.7112.3177.4-59.1170.1000109.7R90 I114 S118R90-I121 PolarHBondContact NH2-O 3.21Å; I114-I121 HydrophobicContact CG2-CB 4.01Å; I114-I121 HydrophobicContact CG2-CD1 3.67Å; I114-I121 HydrophobicContact CG2-CG1 4.43Å; I114-I121 HydrophobicContact CG2-CG2 3.88Å; S118-I121 VanDerWaalsContact OG-CB 3.3Å; S118-I121 WeakPolarHBondContact OG-CB 3.26Å; S118-I121 WeakPolarHBondContact OG-CG1 3.36Å; S118-I121 PolarHBondContact OG-N 2.79Å
122P94.4Very high91.5Very high56 Ų5663.8 Ų63.836%0.36432%0.323SS..PPolyproline II helixtrans-74.5156.6175.232.5-35.4000111.2D120D120-P122 VanDerWaalsContact O-CD 3.24Å; D120-P122 WeakPolarHBondContact O-CD 3.36Å
123P94.5Very high92.2Very high3 Ų364.9 Ų64.92%0.01933%0.326CS..PPolyproline II helixtrans-71169.516732.1-31.9000110.7L95 W115 C153 E154L95-P123 HydrophobicContact CD1-CB 3.63Å; L95-P123 HydrophobicContact CG-CB 3.98Å; W115-P123 HydrophobicContact CG-CB 4.46Å; P123-C153 HydrophobicContact CG-CB 3.99Å; P123-C153 PolarHBondContact O-SG 3.25Å; P123-C153 VanDerWaalsContact O-SG 3.33Å; P123-E154 WeakPolarHBondContact CD-O 3.12Å
124P95.3Very high92.9Very high54 Ų5465.6 Ų65.635%0.35134%0.335SS..PPolyproline II helixtrans-52.3140.7172.3-26.335.1000111.8G93 G94 W115G93-P124 CarbonylContact C-O 3.57Å; G93-P124 WeakPolarHBondContact CA-O 3.27Å; G94-P124 PolarHBondContact N-O 3.27Å; W115-P124 HydrophobicContact CZ2-CG 4.13Å
125P97.5Very high93.4Very high77 Ų7766 Ų6650%0.534%0.343SS..PPolyproline II helixtrans-67.8147.5-179.527.6-34.4000112.3N127P125-N127 PolarHBondContact O-N 2.83Å
126M98.1Very high94Very high4 Ų464.8 Ų64.82%0.0234%0.339CS..PPolyproline II helixtrans-75.7119.2169.6-171.9176.2-71.100109.8G93 T96 H130 Y133 I136 T152G93-M126 WeakPolarHBondContact O-CE 3.24Å; T96-M126 HydrophobicContact CG2-CE 3.97Å; M126-H130 HydrophobicContact CG-CB 3.64Å; M126-H130 HydrophobicContact SD-CB 4.47Å; M126-Y133 HydrophobicContact CG-CD2 4.2Å; M126-Y133 HydrophobicContact SD-CD2 4.46Å; M126-I136 HydrophobicContact CE-CD1 3.97Å; M126-I136 HydrophobicContact SD-CD1 4.43Å; M126-T152 WeakPolarHBondContact CB-O 3.38Å; M126-T152 PolarHBondContact N-O 2.92Å
127N96.8Very high94.8Very high93 Ų9362 Ų6250%0.49733%0.331SS..PPolyproline II helixtrans-97.8171.3175.266.747.8000111.9P125 K129 H130 Y133P125-N127 PolarHBondContact O-N 2.83Å; N127-K129 PolarHBondContact O-N 2.57Å; N127-K129 WeakPolarHBondContact OD1-CA 3.27Å; N127-K129 WeakPolarHBondContact OD1-CB 3.33Å; N127-K129 PolarHBondContact OD1-N 3.48Å; N127-H130 WeakPolarHBondContact O-CB 3.4Å; N127-H130 PolarHBondContact O-N 3.13Å; N127-H130 PolarHBondContact OD1-N 3.25Å; N127-Y133 WeakPolarHBondContact O-CB 3.32Å; N127-Y133 WeakPolarHBondContact O-CD2 3.32Å
128E96.9Very high95.6Very high142 Ų14267.1 Ų67.166%0.66435%0.353SS*.THydrogen-bonded Turntrans-63.9-20.8-177.1-54.1-166.6156.100114.5H130 Y133E128-H130 VanDerWaalsContact C-N 3.31Å; E128-Y133 HydrophobicContact CB-CD1 4.23Å; E128-Y133 HydrophobicContact CB-CE1 4.06Å; E128-Y133 HydrophobicContact CG-CE1 3.89Å; E128-Y133 HydrophobicContact CG-CE2 4.13Å
129K97.4Very high96.2Very high200 Ų20068.5 Ų68.587%0.8736%0.358SS*.THydrogen-bonded Turntrans-84.1-7.4177.4-57.9-178.7179.1-179.50112.5N127N127-K129 PolarHBondContact O-N 2.57Å; N127-K129 WeakPolarHBondContact OD1-CA 3.27Å; N127-K129 WeakPolarHBondContact OD1-CB 3.33Å; N127-K129 PolarHBondContact OD1-N 3.48Å
130H98.1Very high96.6Very high28 Ų2877.4 Ų77.413%0.1339%0.391CS..SBendtrans-67.5136.5-178.7-173-91000110.6T96 M126 N127 E128 Y132 Y133T96-H130 PolarHBondContact O-CE1 3.34Å; T96-H130 PolarHBondContact O-NE2 3.38Å; M126-H130 HydrophobicContact CG-CB 3.64Å; M126-H130 HydrophobicContact SD-CB 4.47Å; N127-H130 WeakPolarHBondContact O-CB 3.4Å; N127-H130 PolarHBondContact O-N 3.13Å; N127-H130 PolarHBondContact OD1-N 3.25Å; E128-H130 VanDerWaalsContact C-N 3.31Å; H130-Y132 AromaticContact CE1-CD2 3.69Å; H130-Y132 PolarHBondContact ND1-N 2.77Å; H130-Y132 PolarHBondContact O-N 2.85Å; H130-Y133 VanDerWaalsContact O-CB 3.32Å; H130-Y133 WeakPolarHBondContact O-CB 3.39Å; H130-Y133 PolarHBondContact O-N 2.74Å
131P98Very high96.8Very high113 Ų11376.7 Ų76.773%0.73438%0.381SS*.THydrogen-bonded Turntrans-55.6-29.9-174.2-27.834.8000114.7
132Y98Very high97.1Very high66 Ų6673.7 Ų73.726%0.25937%0.365SS..THydrogen-bonded Turntrans-101.56-179.6-59.7-81.1000114.2W16 F26 H130 N134 S135 I136W16-Y132 HydrophobicContact CH2-CD1 4.2Å; W16-Y132 HydrophobicContact CH2-CD2 4.31Å; W16-Y132 AromaticContact CH2-CE1 3.73Å; W16-Y132 HydrophobicContact CH2-CE1 3.73Å; W16-Y132 AromaticContact CH2-CE2 3.86Å; W16-Y132 HydrophobicContact CH2-CE2 3.86Å; W16-Y132 HydrophobicContact CH2-CG 4.47Å; W16-Y132 AromaticContact CH2-CZ 3.54Å; W16-Y132 AromaticContact CZ2-CE1 3.78Å; W16-Y132 HydrophobicContact CZ2-CE1 3.78Å; W16-Y132 HydrophobicContact CZ2-CE2 4.38Å; W16-Y132 AromaticContact CZ2-CZ 3.64Å; W16-Y132 WeakPolarHBondContact CZ2-OH 3.49Å; F26-Y132 AromaticContact CD2-CD1 3.6Å; F26-Y132 HydrophobicContact CD2-CD1 3.6Å; F26-Y132 AromaticContact CD2-CE1 3.92Å; F26-Y132 HydrophobicContact CD2-CE1 3.92Å; F26-Y132 HydrophobicContact CD2-CG 4.43Å; F26-Y132 AromaticContact CE2-CD1 3.72Å; F26-Y132 HydrophobicContact CE2-CD1 3.72Å; F26-Y132 AromaticContact CE2-CE1 3.68Å; F26-Y132 HydrophobicContact CE2-CE1 3.68Å; F26-Y132 HydrophobicContact CZ-CE1 4.39Å; H130-Y132 AromaticContact CE1-CD2 3.69Å; H130-Y132 PolarHBondContact ND1-N 2.77Å; H130-Y132 PolarHBondContact O-N 2.85Å; Y132-N134 PolarHBondContact O-N 3.46Å; Y132-S135 PolarHBondContact O-N 3.49Å; Y132-S135 PolarHBondContact O-OG 2.95Å; Y132-I136 WeakPolarHBondContact O-CB 2.97Å; Y132-I136 WeakPolarHBondContact O-CG1 3.23Å; Y132-I136 PolarHBondContact O-N 3.17Å
133Y98.1Very high97.2Very high28 Ų2874.9 Ų74.911%0.1138%0.38CS..Hα-helixtrans-60.5-49-177.6176.4-95000111.7M126 N127 E128 H130 S135 I136 S137 K138M126-Y133 HydrophobicContact CG-CD2 4.2Å; M126-Y133 HydrophobicContact SD-CD2 4.46Å; N127-Y133 WeakPolarHBondContact O-CB 3.32Å; N127-Y133 WeakPolarHBondContact O-CD2 3.32Å; E128-Y133 HydrophobicContact CB-CD1 4.23Å; E128-Y133 HydrophobicContact CB-CE1 4.06Å; E128-Y133 HydrophobicContact CG-CE1 3.89Å; E128-Y133 HydrophobicContact CG-CE2 4.13Å; H130-Y133 VanDerWaalsContact O-CB 3.32Å; H130-Y133 WeakPolarHBondContact O-CB 3.39Å; H130-Y133 PolarHBondContact O-N 2.74Å; Y133-S135 PolarHBondContact O-N 3.29Å; Y133-I136 PolarHBondContact O-N 3.44Å; Y133-S137 WeakPolarHBondContact CD2-OG 3.44Å; Y133-S137 WeakPolarHBondContact O-CA 2.99Å; Y133-S137 VanDerWaalsContact O-CB 3.32Å; Y133-S137 WeakPolarHBondContact O-CB 3.32Å; Y133-S137 PolarHBondContact O-N 3.38Å; Y133-K138 HydrophobicContact CE1-CD 4.4Å; Y133-K138 HydrophobicContact CE1-CG 4.2Å; Y133-K138 WeakPolarHBondContact OH-CE 3.49Å; Y133-K138 PolarHBondContact OH-NZ 2.76Å
134N97.3Very high97.3Very high116 Ų11678.4 Ų78.462%0.6242%0.416SS*.Hα-helixtrans-66.5-37.3-177.8-72.7-24.2000112.7Y132 I136 K138Y132-N134 PolarHBondContact O-N 3.46Å; N134-I136 VanDerWaalsContact C-N 3.28Å; N134-I136 PolarHBondContact O-N 3.42Å; N134-K138 WeakPolarHBondContact O-CB 3.1Å
135S97.3Very high97.3Very high67 Ų6777.3 Ų77.347%0.46941%0.407SS..Hα-helixtrans-77-12179.9570000114.1Y132 Y133Y132-S135 PolarHBondContact O-N 3.49Å; Y132-S135 PolarHBondContact O-OG 2.95Å; Y133-S135 PolarHBondContact O-N 3.29Å
136I97.4Very high97.2Very high3 Ų380.7 Ų80.72%0.01541%0.414CS..Hα-helixtrans-111.3-66177.9-63170.1000110.1W25 F26 T96 M126 Y132 Y133 N134 K138 E139 Y142W25-I136 HydrophobicContact CB-CG2 3.74Å; W25-I136 HydrophobicContact CE3-CG2 4.33Å; F26-I136 HydrophobicContact CB-CD1 4.14Å; T96-I136 HydrophobicContact CG2-CD1 3.94Å; M126-I136 HydrophobicContact CE-CD1 3.97Å; M126-I136 HydrophobicContact SD-CD1 4.43Å; Y132-I136 WeakPolarHBondContact O-CB 2.97Å; Y132-I136 WeakPolarHBondContact O-CG1 3.23Å; Y132-I136 PolarHBondContact O-N 3.17Å; Y133-I136 PolarHBondContact O-N 3.44Å; N134-I136 VanDerWaalsContact C-N 3.28Å; N134-I136 PolarHBondContact O-N 3.42Å; I136-K138 VanDerWaalsContact C-N 3.3Å; I136-K138 PolarHBondContact O-N 3.1Å; I136-E139 WeakPolarHBondContact O-CB 3.43Å; I136-E139 PolarHBondContact O-N 3.34Å; I136-Y142 WeakPolarHBondContact O-CD2 3.41Å; I136-Y142 WeakPolarHBondContact O-CE2 3.45Å
137S94.8Very high97Very high16 Ų1687.1 Ų87.111%0.11246%0.456CS..Hα-helixtrans-74.1-16.2-169.7-52.30000114.3Y133Y133-S137 WeakPolarHBondContact CD2-OG 3.44Å; Y133-S137 WeakPolarHBondContact O-CA 2.99Å; Y133-S137 VanDerWaalsContact O-CB 3.32Å; Y133-S137 WeakPolarHBondContact O-CB 3.32Å; Y133-S137 PolarHBondContact O-N 3.38Å
138K96.3Very high96.8Very high131 Ų13186.7 Ų86.757%0.5747%0.474SS*.THydrogen-bonded Turntrans-1099.8175-55.3-64.1-176-177.10112.9Y133 N134 I136Y133-K138 HydrophobicContact CE1-CD 4.4Å; Y133-K138 HydrophobicContact CE1-CG 4.2Å; Y133-K138 WeakPolarHBondContact OH-CE 3.49Å; Y133-K138 PolarHBondContact OH-NZ 2.76Å; N134-K138 WeakPolarHBondContact O-CB 3.1Å; I136-K138 VanDerWaalsContact C-N 3.3Å; I136-K138 PolarHBondContact O-N 3.1Å
139E97.9Very high96.7Very high46 Ų4682.5 Ų82.522%0.21545%0.454CS..  trans-74.6133.5-178.1-143.8-80.2-169.800111.2I136 R141 Y142I136-E139 WeakPolarHBondContact O-CB 3.43Å; I136-E139 PolarHBondContact O-N 3.34Å; E139-R141 PolarHBondContact O-N 3.21Å; E139-R141 VanDerWaalsContact O-N 3.1Å; E139-R141 IonicContact OE1-CZ 3.85Å; E139-R141 IonicContact OE1-NE 3.92Å; E139-R141 PolarHBondContact OE1-NE 3.2Å; E139-R141 IonicContact OE1-NH2 3.26Å; E139-R141 PolarHBondContact OE1-NH2 3.2Å; E139-R141 WeakPolarHBondContact OE2-CB 3.42Å; E139-R141 WeakPolarHBondContact OE2-CG 3.14Å; E139-R141 PolarHBondContact OE2-N 2.72Å; E139-R141 IonicContact OE2-NE 3.12Å; E139-R141 PolarHBondContact OE2-NE 3.3Å; E139-R141 VanDerWaalsContact OE2-NE 3.14Å; E139-Y142 HydrophobicContact CB-CD2 3.99Å; E139-Y142 HydrophobicContact CB-CE2 4.2Å; E139-Y142 PolarHBondContact O-N 2.86Å
140R98.2Very high96.7Very high210 Ų21075.5 Ų75.579%0.79243%0.426SS*.G310 helixtrans-54.9-28.1-174.967.5177.9-178.6830.1115.4Y142 A143R140-Y142 PolarHBondContact O-N 2.8Å; R140-A143 VanDerWaalsContact O-CB 3.23Å; R140-A143 WeakPolarHBondContact O-CB 3.43Å; R140-A143 PolarHBondContact O-N 3.15Å
141R98.2Very high96.7Very high82 Ų8275.2 Ų75.231%0.30943%0.427SS..G310 helixtrans-65.4-16.7178.179.3-173.465.9177.49.2112.1D27 V59 E139D27-R141 VanDerWaalsContact CG-NH1 3.28Å; D27-R141 IonicContact OD1-NH1 2.7Å; D27-R141 IonicContact OD2-CZ 3.84Å; D27-R141 IonicContact OD2-NH1 2.98Å; D27-R141 PolarHBondContact OD2-NH1 3.39Å; D27-R141 IonicContact OD2-NH2 3.87Å; D27-R141 PolarHBondContact OD2-NH2 3.46Å; V59-R141 HydrophobicContact CG2-CG 4.25Å; V59-R141 PolarHBondContact O-NH1 3.5Å; E139-R141 PolarHBondContact O-N 3.21Å; E139-R141 VanDerWaalsContact O-N 3.1Å; E139-R141 IonicContact OE1-CZ 3.85Å; E139-R141 IonicContact OE1-NE 3.92Å; E139-R141 PolarHBondContact OE1-NE 3.2Å; E139-R141 IonicContact OE1-NH2 3.26Å; E139-R141 PolarHBondContact OE1-NH2 3.2Å; E139-R141 WeakPolarHBondContact OE2-CB 3.42Å; E139-R141 WeakPolarHBondContact OE2-CG 3.14Å; E139-R141 PolarHBondContact OE2-N 2.72Å; E139-R141 IonicContact OE2-NE 3.12Å; E139-R141 PolarHBondContact OE2-NE 3.3Å; E139-R141 VanDerWaalsContact OE2-NE 3.14Å
142Y98.3Very high96.7Very high12 Ų1273.1 Ų73.15%0.04741%0.412CS..G310 helixtrans-103.3-1.9174.5-52.3-60.5000113.3W25 V59 W85 N88 I136 E139 R140 G144 L145 L150W25-Y142 AromaticContact CE3-CE1 3.84Å; W25-Y142 HydrophobicContact CE3-CE1 3.84Å; W25-Y142 HydrophobicContact CE3-CE2 4.12Å; W25-Y142 AromaticContact CE3-CZ 3.6Å; W25-Y142 HydrophobicContact CH2-CE1 4.32Å; W25-Y142 AromaticContact CZ3-CD1 3.84Å; W25-Y142 HydrophobicContact CZ3-CD1 3.84Å; W25-Y142 AromaticContact CZ3-CE1 3.48Å; W25-Y142 HydrophobicContact CZ3-CE1 3.48Å; W25-Y142 VanDerWaalsContact CZ3-CE1 3.48Å; W25-Y142 HydrophobicContact CZ3-CE2 4.34Å; W25-Y142 HydrophobicContact CZ3-CG 4.41Å; W25-Y142 AromaticContact CZ3-CZ 3.75Å; V59-Y142 HydrophobicContact CG2-CE1 3.65Å; W85-Y142 HydrophobicContact CB-CD1 4.3Å; W85-Y142 HydrophobicContact CB-CE1 4.1Å; N88-Y142 PolarHBondContact ND2-OH 3.16Å; I136-Y142 WeakPolarHBondContact O-CD2 3.41Å; I136-Y142 WeakPolarHBondContact O-CE2 3.45Å; E139-Y142 HydrophobicContact CB-CD2 3.99Å; E139-Y142 HydrophobicContact CB-CE2 4.2Å; E139-Y142 PolarHBondContact O-N 2.86Å; R140-Y142 PolarHBondContact O-N 2.8Å; Y142-G144 PolarHBondContact O-N 3.44Å; Y142-G144 VanDerWaalsContact O-N 3.14Å; Y142-L145 WeakPolarHBondContact O-CB 3.39Å; Y142-L145 PolarHBondContact O-N 2.93Å; Y142-L145 VanDerWaalsContact O-N 3.12Å; Y142-L150 HydrophobicContact CD1-CD1 4.46Å; Y142-L150 HydrophobicContact CG-CD1 4.19Å
143A97Very high96.6Very high82 Ų8271.1 Ų71.168%0.67841%0.408SS*.THydrogen-bonded Turntrans-64.9-20.2-175.300000114R140R140-A143 VanDerWaalsContact O-CB 3.23Å; R140-A143 WeakPolarHBondContact O-CB 3.43Å; R140-A143 PolarHBondContact O-N 3.15Å
144G96.1Very high96.6Very high76 Ų7670 Ų7078%0.78440%0.403SS*.THydrogen-bonded Turntrans-88.3-2.2177.300000115.1Y142Y142-G144 PolarHBondContact O-N 3.44Å; Y142-G144 VanDerWaalsContact O-N 3.14Å
145L95.9Very high96.5Very high31 Ų3164.5 Ų64.516%0.16237%0.374CS..SBendtrans-70.9144.1176.5-87.461.5000110W85 Y142 E149 L150W85-L145 HydrophobicContact CD2-CD2 3.89Å; W85-L145 HydrophobicContact CD2-CG 4.45Å; W85-L145 HydrophobicContact CE3-CD2 4.42Å; W85-L145 HydrophobicContact CG-CD1 4.09Å; W85-L145 HydrophobicContact CG-CD2 4.12Å; W85-L145 HydrophobicContact CG-CG 4.43Å; W85-L145 HydrophobicContact CZ2-CD2 4.14Å; W85-L145 HydrophobicContact CZ2-CG 4.45Å; Y142-L145 WeakPolarHBondContact O-CB 3.39Å; Y142-L145 PolarHBondContact O-N 2.93Å; Y142-L145 VanDerWaalsContact O-N 3.12Å; L145-E149 HydrophobicContact CB-CB 4.13Å; L145-E149 HydrophobicContact CD2-CB 4.23Å; L145-E149 HydrophobicContact CG-CB 4.21Å; L145-L150 HydrophobicContact CD2-CB 4Å; L145-L150 HydrophobicContact CD2-CD1 4.24Å
146K95.8Very high96.3Very high149 Ų14961.5 Ų61.565%0.64835%0.353SS*.PPolyproline II helixtrans-67.7154.1174.1-61.7174.7-178.1174.90110G148 E149K146-G148 PolarHBondContact O-N 3.28Å; K146-E149 HydrophobicContact CB-CG 3.98Å; K146-E149 WeakPolarHBondContact CB-OE2 3.33Å; K146-E149 PolarHBondContact N-OE2 3.47Å; K146-E149 WeakPolarHBondContact O-CB 3.44Å; K146-E149 PolarHBondContact O-N 3.36Å
147P92.6Very high96.2Very high138 Ų13866.7 Ų66.790%0.89638%0.375SS*.THydrogen-bonded Turntrans-50.8128.8170.5-26.535.2000111.1
148G92.9Very high96.3Very high84 Ų8469.2 Ų69.287%0.86639%0.387SS*.THydrogen-bonded Turntrans88-10-17800000115.9K146K146-G148 PolarHBondContact O-N 3.28Å
149E95.5Very high96.4Very high54 Ų5463 Ų6325%0.25236%0.36SS..THydrogen-bonded Turntrans-81.3-27.5177.1-72.6-172.213800113.5W85 R86 L145 K146 P151W85-E149 HydrophobicContact CH2-CB 4.47Å; W85-E149 VanDerWaalsContact CH2-O 3.24Å; W85-E149 WeakPolarHBondContact CH2-O 3.4Å; W85-E149 HydrophobicContact CZ2-CB 4.1Å; R86-E149 IonicContact NH2-OE1 2.95Å; R86-E149 PolarHBondContact NH2-OE1 2.85Å; R86-E149 VanDerWaalsContact NH2-OE1 3.09Å; L145-E149 HydrophobicContact CB-CB 4.13Å; L145-E149 HydrophobicContact CD2-CB 4.23Å; L145-E149 HydrophobicContact CG-CB 4.21Å; K146-E149 HydrophobicContact CB-CG 3.98Å; K146-E149 WeakPolarHBondContact CB-OE2 3.33Å; K146-E149 PolarHBondContact N-OE2 3.47Å; K146-E149 WeakPolarHBondContact O-CB 3.44Å; K146-E149 PolarHBondContact O-N 3.36Å; E149-P151 WeakPolarHBondContact O-CD 3.46Å
150L96.9Very high96.2Very high53 Ų5361.5 Ų61.528%0.27735%0.354SS..SBendtrans-79.4108178.3179.662.3000109.7W25 Y142 L145W25-L150 HydrophobicContact CE3-CD1 4.15Å; W25-L150 HydrophobicContact CH2-CD1 3.95Å; W25-L150 HydrophobicContact CZ3-CD1 3.3Å; Y142-L150 HydrophobicContact CD1-CD1 4.46Å; Y142-L150 HydrophobicContact CG-CD1 4.19Å; L145-L150 HydrophobicContact CD2-CB 4Å; L145-L150 HydrophobicContact CD2-CD1 4.24Å
151P97.7Very high96.1Very high23 Ų2354.7 Ų54.715%0.14934%0.342CS..  trans-75.6145.2-177.531.6-35.3000111.5W25 H91 E149 E154W25-P151 HydrophobicContact CH2-CG 3.84Å; W25-P151 HydrophobicContact CZ2-CG 3.66Å; H91-P151 HydrophobicContact CB-CG 4.27Å; H91-P151 PolarHBondContact CD2-O 3.23Å; H91-P151 VanDerWaalsContact CD2-O 3.23Å; H91-P151 PolarHBondContact NE2-O 3.33Å; E149-P151 WeakPolarHBondContact O-CD 3.46Å; P151-E154 HydrophobicContact CB-CG 3.69Å; P151-E154 HydrophobicContact CG-CG 3.74Å
152T97.8Very high96.1Very high68 Ų6851.5 Ų51.542%0.41733%0.33SS..SBendtrans-86.2-20167.654.80000112.5G93 M126G93-T152 WeakPolarHBondContact CA-O 3.31Å; M126-T152 WeakPolarHBondContact CB-O 3.38Å; M126-T152 PolarHBondContact N-O 2.92Å
153C97.4Very high96Very high25 Ų2551 Ų5117%0.16933%0.329CS..SBendtrans-162.6161.2170.555.40000108.9H91 P123H91-C153 CarbonylContact O-C 3.53Å; H91-C153 WeakPolarHBondContact O-CA 3.32Å; P123-C153 HydrophobicContact CG-CB 3.99Å; P123-C153 PolarHBondContact O-SG 3.25Å; P123-C153 VanDerWaalsContact O-SG 3.33Å
154E97.4Very high96Very high4 Ų448.8 Ų48.82%0.01931%0.305CS..  trans-135.1139.6176.7-68.6178.9117.700110.3R90 H91 P123 P151 D158 R162R90-E154 HydrophobicContact CG-CB 4.09Å; R90-E154 WeakPolarHBondContact CG-O 3.41Å; R90-E154 PolarHBondContact NE-O 2.6Å; R90-E154 PolarHBondContact NH2-O 2.89Å; H91-E154 HydrophobicContact CB-CB 4.22Å; H91-E154 HydrophobicContact CB-CG 3.85Å; H91-E154 PolarHBondContact N-OE2 3.03Å; H91-E154 PolarHBondContact O-N 3Å; P123-E154 WeakPolarHBondContact CD-O 3.12Å; P151-E154 HydrophobicContact CB-CG 3.69Å; P151-E154 HydrophobicContact CG-CG 3.74Å; E154-D158 HydrophobicContact CB-CB 4.07Å; E154-D158 HydrophobicContact CG-CB 4.27Å; E154-R162 WeakPolarHBondContact OE1-CG 3.24Å; E154-R162 IonicContact OE1-CZ 3.42Å; E154-R162 IonicContact OE1-NE 3.78Å; E154-R162 PolarHBondContact OE1-NE 3.14Å; E154-R162 IonicContact OE1-NH2 3.09Å; E154-R162 PolarHBondContact OE1-NH2 2.71Å; E154-R162 IonicContact OE2-CZ 3.69Å; E154-R162 IonicContact OE2-NE 2.82Å; E154-R162 IonicContact OE2-NH2 3.69Å; E154-R162 PolarHBondContact OE2-NH2 3.23Å; E154-R162 VanDerWaalsContact OE2-NH2 3.08Å
155S95.4Very high96Very high1 Ų147 Ų471%0.00728%0.279CS..  trans-73.7174.4153.768.80000111F119 K157 D158 T159F119-S155 WeakPolarHBondContact O-CB 3.37Å; S155-K157 VanDerWaalsContact C-N 3.28Å; S155-K157 WeakPolarHBondContact OG-CB 3.4Å; S155-K157 PolarHBondContact OG-N 3.22Å; S155-D158 VanDerWaalsContact CB-OD2 3.3Å; S155-D158 WeakPolarHBondContact CB-OD2 3.44Å; S155-D158 PolarHBondContact N-OD2 2.73Å; S155-D158 PolarHBondContact O-N 3.03Å; S155-D158 PolarHBondContact OG-N 2.84Å; S155-D158 PolarHBondContact OG-OD2 3.29Å; S155-T159 PolarHBondContact O-N 2.89Å; S155-T159 VanDerWaalsContact O-N 3.12Å; S155-T159 PolarHBondContact O-OG1 3.01Å
156L92.6Very high96.1Very high4 Ų446.3 Ų46.32%0.02128%0.275CS..Hα-helixtrans-65.5-38169.5177.960.2000110.2F119 D158 T159 I160 N188 I205F119-L156 HydrophobicContact CD2-CB 4.38Å; F119-L156 HydrophobicContact CD2-CD2 4.09Å; F119-L156 HydrophobicContact CD2-CG 4.2Å; F119-L156 CarbonylContact O-C 3.59Å; F119-L156 PolarHBondContact O-N 3Å; F119-L156 VanDerWaalsContact O-N 3.12Å; L156-D158 PolarHBondContact O-N 3.31Å; L156-T159 WeakPolarHBondContact O-CB 3.47Å; L156-T159 PolarHBondContact O-N 3.2Å; L156-I160 HydrophobicContact CD1-CD1 4.21Å; L156-I160 HydrophobicContact CD1-CG1 4.38Å; L156-I160 HydrophobicContact CG-CD1 3.94Å; L156-I160 WeakPolarHBondContact O-CG1 3.46Å; L156-I160 PolarHBondContact O-N 2.99Å; L156-N188 HydrophobicContact CD1-CB 3.94Å; L156-I205 HydrophobicContact CD2-CG1 4.18Å; L156-I205 HydrophobicContact CD2-CG2 4.05Å
157K95.5Very high96.2Very high112 Ų11239.3 Ų39.349%0.48725%0.245SC..Hα-helixtrans-58.1-45174.4-176-177.9-179.81800111.8F119 D120 S155 I160 A161F119-K157 HydrophobicContact CD1-CB 4.13Å; F119-K157 HydrophobicContact CD1-CD 4.5Å; F119-K157 HydrophobicContact CE1-CB 3.77Å; F119-K157 HydrophobicContact CE1-CD 3.95Å; F119-K157 HydrophobicContact CE1-CG 3.83Å; F119-K157 HydrophobicContact CE2-CB 4.32Å; F119-K157 HydrophobicContact CZ-CB 3.87Å; F119-K157 HydrophobicContact CZ-CG 4Å; F119-K157 WeakPolarHBondContact O-CB 3.28Å; F119-K157 PolarHBondContact O-N 2.99Å; D120-K157 HydrophobicContact CB-CD 4.24Å; S155-K157 VanDerWaalsContact C-N 3.28Å; S155-K157 WeakPolarHBondContact OG-CB 3.4Å; S155-K157 PolarHBondContact OG-N 3.22Å; K157-I160 WeakPolarHBondContact O-CB 3.49Å; K157-I160 PolarHBondContact O-N 3.36Å; K157-A161 WeakPolarHBondContact O-CB 3.12Å; K157-A161 PolarHBondContact O-N 2.96Å
158D97.2Very high96.4Very high68 Ų6836.4 Ų36.436%0.36422%0.222SC..Hα-helixtrans-65.6-44.7178.2-57-41.2000111.1E154 S155 L156 I160 A161 R162E154-D158 HydrophobicContact CB-CB 4.07Å; E154-D158 HydrophobicContact CG-CB 4.27Å; S155-D158 VanDerWaalsContact CB-OD2 3.3Å; S155-D158 WeakPolarHBondContact CB-OD2 3.44Å; S155-D158 PolarHBondContact N-OD2 2.73Å; S155-D158 PolarHBondContact O-N 3.03Å; S155-D158 PolarHBondContact OG-N 2.84Å; S155-D158 PolarHBondContact OG-OD2 3.29Å; L156-D158 PolarHBondContact O-N 3.31Å; D158-I160 VanDerWaalsContact C-N 3.25Å; D158-I160 PolarHBondContact O-N 2.95Å; D158-A161 WeakPolarHBondContact O-CB 3.49Å; D158-A161 PolarHBondContact O-N 3.33Å; D158-A161 VanDerWaalsContact O-N 3.09Å; D158-R162 WeakPolarHBondContact O-CG 3.43Å; D158-R162 PolarHBondContact O-N 3.12Å
159T96.9Very high96.7Very high0 Ų038.8 Ų38.80%021%0.21CC..Hα-helixtrans-54.9-44.3175.4-57.40000110.6S155 L156 R162 A163 N188S155-T159 PolarHBondContact O-N 2.89Å; S155-T159 VanDerWaalsContact O-N 3.12Å; S155-T159 PolarHBondContact O-OG1 3.01Å; L156-T159 WeakPolarHBondContact O-CB 3.47Å; L156-T159 PolarHBondContact O-N 3.2Å; T159-R162 VanDerWaalsContact O-CD 3.31Å; T159-R162 WeakPolarHBondContact O-CD 3.48Å; T159-R162 WeakPolarHBondContact O-CG 3.33Å; T159-R162 PolarHBondContact O-NE 2.84Å; T159-A163 VanDerWaalsContact O-CB 3.22Å; T159-A163 WeakPolarHBondContact O-CB 3.24Å; T159-A163 PolarHBondContact O-N 2.68Å; T159-A163 VanDerWaalsContact O-N 3.1Å; T159-N188 HydrophobicContact CG2-CB 4.46Å
160I95Very high96.8Very high16 Ų1640.5 Ų40.58%0.08222%0.218CC..Hα-helixtrans-65.5-46.7176.5-69.5169.8000111F119 L156 K157 D158 R162 A163 L164 K195F119-I160 HydrophobicContact CE2-CD1 3.72Å; F119-I160 HydrophobicContact CZ-CD1 4.46Å; L156-I160 HydrophobicContact CD1-CD1 4.21Å; L156-I160 HydrophobicContact CD1-CG1 4.38Å; L156-I160 HydrophobicContact CG-CD1 3.94Å; L156-I160 WeakPolarHBondContact O-CG1 3.46Å; L156-I160 PolarHBondContact O-N 2.99Å; K157-I160 WeakPolarHBondContact O-CB 3.49Å; K157-I160 PolarHBondContact O-N 3.36Å; D158-I160 VanDerWaalsContact C-N 3.25Å; D158-I160 PolarHBondContact O-N 2.95Å; I160-R162 PolarHBondContact O-N 2.99Å; I160-A163 PolarHBondContact O-N 3.04Å; I160-A163 VanDerWaalsContact O-N 3.08Å; I160-L164 HydrophobicContact CG2-CD1 3.5Å; I160-L164 VanDerWaalsContact CG2-CD1 3.5Å; I160-L164 HydrophobicContact CG2-CG 3.81Å; I160-L164 WeakPolarHBondContact O-CG 3.35Å; I160-L164 PolarHBondContact O-N 3.26Å; I160-K195 HydrophobicContact CD1-CD 3.78Å
161A96.6Very high96.9Very high66 Ų6638 Ų3855%0.54521%0.205SC..Hα-helixtrans-59.3-34.3-177.800000112.5K157 D158 P165K157-A161 WeakPolarHBondContact O-CB 3.12Å; K157-A161 PolarHBondContact O-N 2.96Å; D158-A161 WeakPolarHBondContact O-CB 3.49Å; D158-A161 PolarHBondContact O-N 3.33Å; D158-A161 VanDerWaalsContact O-N 3.09Å; A161-P165 WeakPolarHBondContact O-CD 3.15Å; A161-P165 WeakPolarHBondContact O-CG 3.46Å
162R97.4Very high96.9Very high16 Ų1637.7 Ų37.76%0.0620%0.203CC..Hα-helixtrans-86.7-22174.360.675.5174.6162.2-3.1114.8W85 R86 N88 E89 E154 D158 T159 I160W85-R162 HydrophobicContact CH2-CB 3.8Å; W85-R162 HydrophobicContact CH2-CG 4.15Å; W85-R162 HydrophobicContact CZ3-CB 4.04Å; W85-R162 HydrophobicContact CZ3-CG 3.86Å; R86-R162 VanDerWaalsContact C-NH1 3.34Å; R86-R162 WeakPolarHBondContact CB-O 3.13Å; R86-R162 WeakPolarHBondContact CD-O 3.46Å; R86-R162 WeakPolarHBondContact CG-O 3.44Å; R86-R162 PolarHBondContact NH1-O 2.87Å; R86-R162 PolarHBondContact O-NH1 2.89Å; N88-R162 VanDerWaalsContact O-CZ 3.28Å; N88-R162 PolarHBondContact O-NH1 3.21Å; N88-R162 PolarHBondContact O-NH2 3.07Å; E89-R162 PolarHBondContact O-NH2 2.95Å; E89-R162 VanDerWaalsContact O-NH2 3.09Å; E154-R162 WeakPolarHBondContact OE1-CG 3.24Å; E154-R162 IonicContact OE1-CZ 3.42Å; E154-R162 IonicContact OE1-NE 3.78Å; E154-R162 PolarHBondContact OE1-NE 3.14Å; E154-R162 IonicContact OE1-NH2 3.09Å; E154-R162 PolarHBondContact OE1-NH2 2.71Å; E154-R162 IonicContact OE2-CZ 3.69Å; E154-R162 IonicContact OE2-NE 2.82Å; E154-R162 IonicContact OE2-NH2 3.69Å; E154-R162 PolarHBondContact OE2-NH2 3.23Å; E154-R162 VanDerWaalsContact OE2-NH2 3.08Å; D158-R162 WeakPolarHBondContact O-CG 3.43Å; D158-R162 PolarHBondContact O-N 3.12Å; T159-R162 VanDerWaalsContact O-CD 3.31Å; T159-R162 WeakPolarHBondContact O-CD 3.48Å; T159-R162 WeakPolarHBondContact O-CG 3.33Å; T159-R162 PolarHBondContact O-NE 2.84Å; I160-R162 PolarHBondContact O-N 2.99Å
163A97.1Very high96.9Very high2 Ų237.2 Ų37.22%0.01720%0.201CC..Hα-helixtrans-83.6-38.4-179.800000112.7R86 T159 I160 F166 W167R86-A163 WeakPolarHBondContact O-CA 3.22Å; R86-A163 WeakPolarHBondContact O-CB 3.47Å; T159-A163 VanDerWaalsContact O-CB 3.22Å; T159-A163 WeakPolarHBondContact O-CB 3.24Å; T159-A163 PolarHBondContact O-N 2.68Å; T159-A163 VanDerWaalsContact O-N 3.1Å; I160-A163 PolarHBondContact O-N 3.04Å; I160-A163 VanDerWaalsContact O-N 3.08Å; A163-F166 PolarHBondContact O-N 3.39Å; A163-W167 PolarHBondContact O-N 3.48Å
164L95.8Very high96.9Very high35 Ų3538.1 Ų38.118%0.18320%0.203CC..Hα-helixtrans-63.8-37.2-177.1-74.5-178.7000114.9I160 F166 W167 N168 H196I160-L164 HydrophobicContact CG2-CD1 3.5Å; I160-L164 VanDerWaalsContact CG2-CD1 3.5Å; I160-L164 HydrophobicContact CG2-CG 3.81Å; I160-L164 WeakPolarHBondContact O-CG 3.35Å; I160-L164 PolarHBondContact O-N 3.26Å; L164-F166 VanDerWaalsContact C-N 3.31Å; L164-F166 PolarHBondContact O-N 3.28Å; L164-W167 WeakPolarHBondContact O-CB 3.39Å; L164-W167 PolarHBondContact O-N 3.4Å; L164-N168 WeakPolarHBondContact O-CB 3.28Å; L164-N168 PolarHBondContact O-N 3.31Å; L164-N168 PolarHBondContact O-ND2 3.42Å; L164-H196 HydrophobicContact CD2-CB 3.65Å
165P96.9Very high97Very high37 Ų3738 Ų3824%0.2420%0.202CC..Hα-helixtrans-55.7-47.1172.2-28.636.3000111.8A161 W167 N168 E169A161-P165 WeakPolarHBondContact O-CD 3.15Å; A161-P165 WeakPolarHBondContact O-CG 3.46Å; P165-W167 PolarHBondContact O-N 3.35Å; P165-N168 PolarHBondContact O-N 3.41Å; P165-E169 VanDerWaalsContact O-CB 3.23Å; P165-E169 WeakPolarHBondContact O-CB 3.49Å; P165-E169 VanDerWaalsContact O-CG 3.27Å; P165-E169 WeakPolarHBondContact O-CG 3.29Å; P165-E169 PolarHBondContact O-N 3.28Å
166F98Very high97Very high17 Ų1743.9 Ų43.98%0.07523%0.228CC..Hα-helixtrans-63.3-41.4176.6-172.9-102000112.8Y56 V82 T84 R86 L87 A163 L164 E170 I171Y56-F166 AromaticContact CD1-CE1 3.63Å; Y56-F166 HydrophobicContact CD1-CE1 3.63Å; Y56-F166 AromaticContact CD1-CZ 3.59Å; Y56-F166 HydrophobicContact CD1-CZ 3.59Å; Y56-F166 HydrophobicContact CE1-CE1 4.1Å; Y56-F166 AromaticContact CE1-CZ 3.82Å; Y56-F166 HydrophobicContact CE1-CZ 3.82Å; Y56-F166 HydrophobicContact CG-CE1 4.35Å; V82-F166 HydrophobicContact CG1-CE2 4.47Å; V82-F166 HydrophobicContact CG1-CZ 4.03Å; T84-F166 HydrophobicContact CG2-CD1 3.69Å; T84-F166 HydrophobicContact CG2-CD2 3.9Å; T84-F166 HydrophobicContact CG2-CE1 3.43Å; T84-F166 VanDerWaalsContact CG2-CE1 3.43Å; T84-F166 HydrophobicContact CG2-CE2 3.64Å; T84-F166 HydrophobicContact CG2-CG 3.92Å; T84-F166 HydrophobicContact CG2-CZ 3.4Å; T84-F166 VanDerWaalsContact CG2-CZ 3.4Å; R86-F166 HydrophobicContact CB-CB 3.84Å; R86-F166 HydrophobicContact CB-CG 4.29Å; R86-F166 HydrophobicContact CG-CB 4.42Å; L87-F166 HydrophobicContact CD1-CD1 4.3Å; L87-F166 HydrophobicContact CD1-CE1 3.91Å; L87-F166 HydrophobicContact CD2-CD1 4.49Å; L87-F166 HydrophobicContact CG-CD1 4.14Å; L87-F166 HydrophobicContact CG-CE1 4.23Å; A163-F166 PolarHBondContact O-N 3.39Å; L164-F166 VanDerWaalsContact C-N 3.31Å; L164-F166 PolarHBondContact O-N 3.28Å; F166-E170 HydrophobicContact CD2-CB 4.06Å; F166-E170 HydrophobicContact CD2-CG 3.7Å; F166-E170 HydrophobicContact CE1-CB 4.5Å; F166-E170 HydrophobicContact CE2-CB 3.84Å; F166-E170 HydrophobicContact CE2-CG 3.59Å; F166-E170 HydrophobicContact CZ-CB 4.06Å; F166-E170 HydrophobicContact CZ-CG 4.31Å; F166-E170 WeakPolarHBondContact O-CB 3.3Å; F166-E170 PolarHBondContact O-N 2.92Å; F166-I171 HydrophobicContact CD1-CD1 3.9Å; F166-I171 HydrophobicContact CD1-CG1 4.09Å; F166-I171 HydrophobicContact CE1-CD1 3.82Å; F166-I171 HydrophobicContact CE1-CG1 3.88Å; F166-I171 PolarHBondContact O-N 3Å
167W97.6Very high97.2Very high3 Ų347.3 Ų47.31%0.01126%0.256CS..Iπ-helixtrans-57.5-49.7174.2166.7-95.8000111.5L6 A163 L164 P165 I171 V172 I175 I183 I193 H196 L197L6-W167 HydrophobicContact CD2-CH2 3.7Å; L6-W167 HydrophobicContact CD2-CZ3 3.85Å; A163-W167 PolarHBondContact O-N 3.48Å; L164-W167 WeakPolarHBondContact O-CB 3.39Å; L164-W167 PolarHBondContact O-N 3.4Å; P165-W167 PolarHBondContact O-N 3.35Å; W167-I171 HydrophobicContact CE3-CB 4.04Å; W167-I171 HydrophobicContact CE3-CD1 4.05Å; W167-I171 HydrophobicContact CE3-CG2 3.84Å; W167-I171 HydrophobicContact CZ3-CB 4.44Å; W167-I171 HydrophobicContact CZ3-CG2 3.74Å; W167-I171 WeakPolarHBondContact O-CB 3.3Å; W167-I171 PolarHBondContact O-N 3.24Å; W167-V172 HydrophobicContact CD2-CG2 4.26Å; W167-V172 HydrophobicContact CG-CG2 4.36Å; W167-V172 HydrophobicContact CZ2-CG2 4.02Å; W167-V172 WeakPolarHBondContact O-CB 3.05Å; W167-V172 VanDerWaalsContact O-CG2 3.31Å; W167-V172 WeakPolarHBondContact O-CG2 3.29Å; W167-V172 PolarHBondContact O-N 3.15Å; W167-I175 HydrophobicContact CH2-CD1 3.68Å; W167-I175 HydrophobicContact CZ2-CD1 4.36Å; W167-I175 HydrophobicContact CZ3-CD1 4.17Å; W167-I183 HydrophobicContact CE3-CD1 4.39Å; W167-I183 HydrophobicContact CZ3-CD1 4.04Å; W167-I193 HydrophobicContact CD2-CG2 4.12Å; W167-I193 HydrophobicContact CE3-CD1 4.21Å; W167-I193 HydrophobicContact CE3-CG1 4.37Å; W167-I193 HydrophobicContact CE3-CG2 3.67Å; W167-I193 HydrophobicContact CH2-CG2 4.17Å; W167-I193 HydrophobicContact CZ3-CG2 3.69Å; W167-H196 AromaticContact CD1-CD2 3.89Å; W167-H196 AromaticContact NE1-CD2 3.53Å; W167-H196 AromaticContact NE1-NE2 3.76Å; W167-L197 HydrophobicContact CH2-CD1 4.26Å; W167-L197 HydrophobicContact CH2-CD2 4.04Å; W167-L197 HydrophobicContact CH2-CG 4.45Å; W167-L197 HydrophobicContact CZ2-CD2 3.6Å; W167-L197 HydrophobicContact CZ2-CG 4.23Å
168N97.3Very high97.3Very high77 Ų7744.2 Ų44.241%0.41226%0.256SS..Iπ-helixtrans-72.5-38.7-176.1-72.1-33.5000113.6L164 P165 P173L164-N168 WeakPolarHBondContact O-CB 3.28Å; L164-N168 PolarHBondContact O-N 3.31Å; L164-N168 PolarHBondContact O-ND2 3.42Å; P165-N168 PolarHBondContact O-N 3.41Å; N168-P173 WeakPolarHBondContact O-CD 3.38Å
169E98.1Very high97.3Very high133 Ų13344.7 Ų44.762%0.62126%0.255SS*.Iπ-helixtrans-87-34.3-172.5-66.6165.9-159.800112.2P165 P173P165-E169 VanDerWaalsContact O-CB 3.23Å; P165-E169 WeakPolarHBondContact O-CB 3.49Å; P165-E169 VanDerWaalsContact O-CG 3.27Å; P165-E169 WeakPolarHBondContact O-CG 3.29Å; P165-E169 PolarHBondContact O-N 3.28Å; E169-P173 WeakPolarHBondContact O-CG 3.44Å
170E98.4Very high97.4Very high90 Ų9048.2 Ų48.242%0.42127%0.268SS..Iπ-helixtrans-110.8-48.4-174-61.3-62.7151.500112.7Y56 F166 Q174Y56-E170 PolarHBondContact OH-O 3.2Å; F166-E170 HydrophobicContact CD2-CB 4.06Å; F166-E170 HydrophobicContact CD2-CG 3.7Å; F166-E170 HydrophobicContact CE1-CB 4.5Å; F166-E170 HydrophobicContact CE2-CB 3.84Å; F166-E170 HydrophobicContact CE2-CG 3.59Å; F166-E170 HydrophobicContact CZ-CB 4.06Å; F166-E170 HydrophobicContact CZ-CG 4.31Å; F166-E170 WeakPolarHBondContact O-CB 3.3Å; F166-E170 PolarHBondContact O-N 2.92Å; E170-Q174 WeakPolarHBondContact O-CG 3.41Å
171I98.3Very high97.6Very high0 Ų047.5 Ų47.50%027%0.265CS..Iπ-helixtrans-80.3-48.6-171-55.4-176.3000111.5Y56 F166 W167 Q174 I175 V181 I183Y56-I171 HydrophobicContact CD1-CD1 4.5Å; Y56-I171 HydrophobicContact CD1-CG1 4.21Å; Y56-I171 HydrophobicContact CD2-CD1 4.19Å; Y56-I171 HydrophobicContact CD2-CG1 4.01Å; Y56-I171 HydrophobicContact CE1-CG1 4.11Å; Y56-I171 HydrophobicContact CE2-CB 4.37Å; Y56-I171 HydrophobicContact CE2-CG1 3.89Å; Y56-I171 HydrophobicContact CE2-CG2 4.22Å; Y56-I171 HydrophobicContact CG-CD1 4.15Å; Y56-I171 HydrophobicContact CG-CG1 4.16Å; F166-I171 HydrophobicContact CD1-CD1 3.9Å; F166-I171 HydrophobicContact CD1-CG1 4.09Å; F166-I171 HydrophobicContact CE1-CD1 3.82Å; F166-I171 HydrophobicContact CE1-CG1 3.88Å; F166-I171 PolarHBondContact O-N 3Å; W167-I171 HydrophobicContact CE3-CB 4.04Å; W167-I171 HydrophobicContact CE3-CD1 4.05Å; W167-I171 HydrophobicContact CE3-CG2 3.84Å; W167-I171 HydrophobicContact CZ3-CB 4.44Å; W167-I171 HydrophobicContact CZ3-CG2 3.74Å; W167-I171 WeakPolarHBondContact O-CB 3.3Å; W167-I171 PolarHBondContact O-N 3.24Å; I171-Q174 WeakPolarHBondContact O-CB 3.45Å; I171-Q174 PolarHBondContact O-N 3.08Å; I171-Q174 VanDerWaalsContact O-N 3.08Å; I171-I175 HydrophobicContact CG2-CD1 3.86Å; I171-I175 HydrophobicContact CG2-CG1 4.27Å; I171-I175 PolarHBondContact O-N 2.92Å; I171-I175 VanDerWaalsContact O-N 3.1Å; I171-V181 HydrophobicContact CG2-CG1 4.15Å; I171-I183 HydrophobicContact CD1-CD1 3.75Å; I171-I183 HydrophobicContact CD1-CG1 4.44Å; I171-I183 HydrophobicContact CG2-CD1 4.3Å
172V97.7Very high97.7Very high17 Ų1744.3 Ų44.310%0.10324%0.239CC..Hα-helixtrans-55-45.4-178158.40000112.7W167 Q174 I175 K176 L224W167-V172 HydrophobicContact CD2-CG2 4.26Å; W167-V172 HydrophobicContact CG-CG2 4.36Å; W167-V172 HydrophobicContact CZ2-CG2 4.02Å; W167-V172 WeakPolarHBondContact O-CB 3.05Å; W167-V172 VanDerWaalsContact O-CG2 3.31Å; W167-V172 WeakPolarHBondContact O-CG2 3.29Å; W167-V172 PolarHBondContact O-N 3.15Å; V172-Q174 VanDerWaalsContact C-N 3.31Å; V172-Q174 PolarHBondContact O-N 3.43Å; V172-I175 PolarHBondContact O-N 3.33Å; V172-K176 HydrophobicContact CG1-CD 4.13Å; V172-K176 PolarHBondContact O-N 3.01Å; V172-L224 HydrophobicContact CB-CD1 4.03Å; V172-L224 HydrophobicContact CG1-CD1 3.63Å; V172-L224 HydrophobicContact CG2-CD1 3.68Å
173P98.1Very high97.7Very high59 Ų5943.6 Ų43.638%0.38324%0.236SC..Hα-helixtrans-60.5-37.5176.5-2737.5000113.2N168 E169 K176 A177N168-P173 WeakPolarHBondContact O-CD 3.38Å; E169-P173 WeakPolarHBondContact O-CG 3.44Å; P173-K176 PolarHBondContact O-N 2.94Å; P173-A177 VanDerWaalsContact O-CB 3.32Å; P173-A177 WeakPolarHBondContact O-CB 3.2Å; P173-A177 PolarHBondContact O-N 3.18Å
174Q98.5Very high97.8Very high44 Ų4443.5 Ų43.521%0.20624%0.235CC..Hα-helixtrans-66.3-43.4176.9-56.1-55-40.800111.5I54 Y56 E170 I171 V172 A177 G178 K179 V181I54-Q174 HydrophobicContact CD1-CG 4.3Å; I54-Q174 HydrophobicContact CG2-CB 4.28Å; I54-Q174 HydrophobicContact CG2-CG 4.41Å; Y56-Q174 WeakPolarHBondContact OH-CG 3.37Å; E170-Q174 WeakPolarHBondContact O-CG 3.41Å; I171-Q174 WeakPolarHBondContact O-CB 3.45Å; I171-Q174 PolarHBondContact O-N 3.08Å; I171-Q174 VanDerWaalsContact O-N 3.08Å; V172-Q174 VanDerWaalsContact C-N 3.31Å; V172-Q174 PolarHBondContact O-N 3.43Å; Q174-A177 PolarHBondContact O-N 2.89Å; Q174-G178 PolarHBondContact O-N 3.32Å; Q174-K179 HydrophobicContact CB-CB 4.3Å; Q174-K179 HydrophobicContact CB-CD 4.26Å; Q174-K179 WeakPolarHBondContact O-CB 3.33Å; Q174-K179 PolarHBondContact O-N 3.03Å; Q174-V181 HydrophobicContact CB-CG2 4.32Å
175I97.9Very high98Very high0 Ų041.8 Ų41.80%023%0.226CC..Hα-helixtrans-61.2-47.6177.4-60.7174000109.8H4 L6 W167 I171 V172 A177 G178 V181 L224H4-I175 HydrophobicContact CB-CG2 3.53Å; H4-I175 PolarHBondContact CE1-O 3.03Å; H4-I175 PolarHBondContact ND1-O 3.2Å; L6-I175 HydrophobicContact CD1-CD1 4.45Å; W167-I175 HydrophobicContact CH2-CD1 3.68Å; W167-I175 HydrophobicContact CZ2-CD1 4.36Å; W167-I175 HydrophobicContact CZ3-CD1 4.17Å; I171-I175 HydrophobicContact CG2-CD1 3.86Å; I171-I175 HydrophobicContact CG2-CG1 4.27Å; I171-I175 PolarHBondContact O-N 2.92Å; I171-I175 VanDerWaalsContact O-N 3.1Å; V172-I175 PolarHBondContact O-N 3.33Å; I175-A177 VanDerWaalsContact C-N 3.25Å; I175-A177 PolarHBondContact O-N 3.2Å; I175-G178 WeakPolarHBondContact O-CA 3.21Å; I175-G178 PolarHBondContact O-N 3.14Å; I175-V181 HydrophobicContact CG1-CB 4.35Å; I175-V181 HydrophobicContact CG1-CG2 3.69Å; I175-L224 HydrophobicContact CB-CD2 4.31Å; I175-L224 HydrophobicContact CG2-CD2 3.54Å
176K96.4Very high98Very high126 Ų12640 Ų4055%0.54822%0.215SC..Hα-helixtrans-63.5-29.8178-74.6-175.7173.7-1790113.2V172 P173 G178 L224V172-K176 HydrophobicContact CG1-CD 4.13Å; V172-K176 PolarHBondContact O-N 3.01Å; P173-K176 PolarHBondContact O-N 2.94Å; K176-G178 PolarHBondContact O-N 2.96Å; K176-L224 HydrophobicContact CG-CD1 4.27Å; K176-L224 HydrophobicContact CG-CD2 4.4Å; K176-L224 HydrophobicContact CG-CG 4.48Å
177A96.9Very high97.8Very high75 Ų7539.4 Ų39.462%0.6221%0.213SC*.THydrogen-bonded Turntrans-73.62171.600000113.6P173 Q174 I175P173-A177 VanDerWaalsContact O-CB 3.32Å; P173-A177 WeakPolarHBondContact O-CB 3.2Å; P173-A177 PolarHBondContact O-N 3.18Å; Q174-A177 PolarHBondContact O-N 2.89Å; I175-A177 VanDerWaalsContact C-N 3.25Å; I175-A177 PolarHBondContact O-N 3.2Å
178G96.6Very high97.6Very high48 Ų4839.5 Ų39.550%0.49521%0.214SC..THydrogen-bonded Turntrans86.94.5177.900000114.5Q174 I175 K176Q174-G178 PolarHBondContact O-N 3.32Å; I175-G178 WeakPolarHBondContact O-CA 3.21Å; I175-G178 PolarHBondContact O-N 3.14Å; K176-G178 PolarHBondContact O-N 2.96Å
179K98.1Very high97.5Very high78 Ų7835.8 Ų35.834%0.33919%0.194SC..  trans-71.3140.7177.7-63.7-166.9-173.5173.10111.4D53 I54 Q174D53-K179 HydrophobicContact CB-CB 4.02Å; D53-K179 HydrophobicContact CB-CD 4.28Å; D53-K179 HydrophobicContact CB-CG 4.17Å; I54-K179 HydrophobicContact CG2-CB 4.44Å; I54-K179 HydrophobicContact CG2-CD 4.28Å; Q174-K179 HydrophobicContact CB-CB 4.3Å; Q174-K179 HydrophobicContact CB-CD 4.26Å; Q174-K179 WeakPolarHBondContact O-CB 3.33Å; Q174-K179 PolarHBondContact O-N 3.03Å
180R98.4Very high97.4Very high73 Ų7329.5 Ų29.528%0.27517%0.165SC..  trans-85.7111.5173.5-59.5165.1-63.717813.6108E51 F52 D53E51-R180 VanDerWaalsContact CB-CZ 3.42Å; E51-R180 WeakPolarHBondContact O-CB 3.45Å; E51-R180 WeakPolarHBondContact O-CD 3.29Å; E51-R180 PolarHBondContact O-NE 2.73Å; E51-R180 IonicContact OE2-CZ 2.77Å; E51-R180 IonicContact OE2-NH1 2.85Å; E51-R180 PolarHBondContact OE2-NH1 3.1Å; E51-R180 IonicContact OE2-NH2 3.51Å; E51-R180 PolarHBondContact OE2-NH2 3.33Å; F52-R180 WeakPolarHBondContact CA-O 3.41Å; D53-R180 PolarHBondContact N-O 3.11Å; D53-R180 IonicContact OD1-CZ 3.58Å; D53-R180 IonicContact OD1-NE 3.44Å; D53-R180 PolarHBondContact OD1-NE 3.5Å; D53-R180 IonicContact OD1-NH2 2.81Å; D53-R180 PolarHBondContact OD1-NH2 3.25Å; D53-R180 VanDerWaalsContact OD2-CB 3.31Å; D53-R180 WeakPolarHBondContact OD2-CB 3.47Å; D53-R180 WeakPolarHBondContact OD2-CG 3.44Å; D53-R180 IonicContact OD2-CZ 3.8Å; D53-R180 PolarHBondContact OD2-N 3.29Å; D53-R180 IonicContact OD2-NE 3.23Å; D53-R180 PolarHBondContact OD2-NE 3.3Å; D53-R180 IonicContact OD2-NH2 3.43Å
181V98.8Very high97.1Very high1 Ų126.4 Ų26.41%0.00615%0.149CC..EExtended strand (participates in β ladder)trans-101.9136.3-170.21790000111L6 V7 I54 Y56 I171 Q174 I175 I183L6-V181 HydrophobicContact CD1-CB 3.87Å; L6-V181 HydrophobicContact CD1-CG1 3.86Å; V7-V181 PolarHBondContact N-O 2.98Å; I54-V181 HydrophobicContact CG2-CG2 3.82Å; Y56-V181 HydrophobicContact CD2-CG1 3.58Å; Y56-V181 HydrophobicContact CE2-CG1 3.72Å; I171-V181 HydrophobicContact CG2-CG1 4.15Å; Q174-V181 HydrophobicContact CB-CG2 4.32Å; I175-V181 HydrophobicContact CG1-CB 4.35Å; I175-V181 HydrophobicContact CG1-CG2 3.69Å; V181-I183 HydrophobicContact CG1-CG1 3.98Å
182L98.9Very high96.8Very high0 Ų026.5 Ų26.50%015%0.15CC..EExtended strand (participates in β ladder)trans-112.5128.6167.417661.3000110.6V7 V9 F52 I54 C55 Y56 L67 I70 L71V7-L182 HydrophobicContact CB-CD1 3.97Å; V7-L182 HydrophobicContact CG1-CD1 3.72Å; V7-L182 CarbonylContact O-C 3.55Å; V7-L182 WeakPolarHBondContact O-CA 3.32Å; V9-L182 HydrophobicContact CG2-CD1 4.14Å; F52-L182 HydrophobicContact CB-CB 4.5Å; F52-L182 HydrophobicContact CD1-CB 3.76Å; F52-L182 HydrophobicContact CD2-CB 4.19Å; F52-L182 HydrophobicContact CD2-CD2 4.08Å; F52-L182 HydrophobicContact CE1-CB 3.96Å; F52-L182 HydrophobicContact CE1-CD1 4.47Å; F52-L182 HydrophobicContact CE2-CB 4.34Å; F52-L182 HydrophobicContact CE2-CD2 3.95Å; F52-L182 HydrophobicContact CG-CB 3.88Å; F52-L182 HydrophobicContact CZ-CB 4.24Å; F52-L182 HydrophobicContact CZ-CD1 4.19Å; F52-L182 HydrophobicContact CZ-CD2 4.39Å; I54-L182 PolarHBondContact O-N 3.05Å; I54-L182 VanDerWaalsContact O-N 3.12Å; C55-L182 CarbonylContact C-O 3.52Å; C55-L182 VanDerWaalsContact CA-O 3.27Å; C55-L182 WeakPolarHBondContact CA-O 3.33Å; Y56-L182 PolarHBondContact N-O 2.97Å; L67-L182 HydrophobicContact CD1-CD2 3.47Å; L67-L182 VanDerWaalsContact CD1-CD2 3.47Å; L67-L182 HydrophobicContact CD1-CG 4.04Å; I70-L182 HydrophobicContact CG2-CD2 3.71Å; L71-L182 HydrophobicContact CD2-CD2 4.48Å
183I98.9Very high96.7Very high0 Ų025.7 Ų25.70%015%0.145CC..EExtended strand (participates in β ladder)trans-118.5114.6174.5-50.5177.6000109.5L6 V7 M8 V9 Y56 L87 W167 I171 V181 A185 L190 I193L6-I183 HydrophobicContact CD1-CD1 3.82Å; L6-I183 HydrophobicContact CD1-CG1 4Å; V7-I183 PolarHBondContact O-N 3.17Å; M8-I183 CarbonylContact C-O 3.59Å; M8-I183 VanDerWaalsContact CA-O 3.29Å; M8-I183 WeakPolarHBondContact CA-O 3.15Å; M8-I183 HydrophobicContact CG-CB 4.15Å; M8-I183 HydrophobicContact CG-CD1 4.19Å; M8-I183 HydrophobicContact CG-CG1 4.44Å; M8-I183 HydrophobicContact SD-CD1 4.32Å; V9-I183 PolarHBondContact N-O 3.39Å; Y56-I183 HydrophobicContact CD2-CG1 4.46Å; Y56-I183 CarbonylContact O-C 3.58Å; Y56-I183 WeakPolarHBondContact O-CA 3.39Å; L87-I183 HydrophobicContact CD1-CG2 4.13Å; W167-I183 HydrophobicContact CE3-CD1 4.39Å; W167-I183 HydrophobicContact CZ3-CD1 4.04Å; I171-I183 HydrophobicContact CD1-CD1 3.75Å; I171-I183 HydrophobicContact CD1-CG1 4.44Å; I171-I183 HydrophobicContact CG2-CD1 4.3Å; V181-I183 HydrophobicContact CG1-CG1 3.98Å; I183-A185 HydrophobicContact CG2-CB 4.2Å; I183-L190 HydrophobicContact CG2-CD2 4.08Å; I183-I193 HydrophobicContact CD1-CD1 4.26Å
184A98.9Very high96.6Very high0 Ų022.9 Ų22.90%013%0.127CC..EExtended strand (participates in β ladder)trans-103.6110.4171.100000109.7V9 Y56 T57 L67V9-A184 WeakPolarHBondContact O-CA 3.45Å; Y56-A184 PolarHBondContact O-N 2.88Å; T57-A184 VanDerWaalsContact CA-O 3.23Å; T57-A184 WeakPolarHBondContact CA-O 3.43Å; T57-A184 VanDerWaalsContact CB-O 3.27Å; T57-A184 WeakPolarHBondContact CB-O 3.07Å; T57-A184 PolarHBondContact OG1-O 3.08Å; L67-A184 HydrophobicContact CB-CB 3.72Å; L67-A184 HydrophobicContact CD1-CB 4.31Å; L67-A184 HydrophobicContact CG-CB 4.47Å
185A98.7Very high96.4Very high0 Ų022.5 Ų22.50%013%0.125CC..EExtended strand (participates in β ladder)trans-146.1-147-174.100000112V9 R10 H11 I183 L190V9-A185 PolarHBondContact O-N 3.49Å; R10-A185 WeakPolarHBondContact CA-O 3.42Å; H11-A185 PolarHBondContact CD2-O 2.97Å; H11-A185 PolarHBondContact N-O 3.41Å; I183-A185 HydrophobicContact CG2-CB 4.2Å; A185-L190 HydrophobicContact CB-CD1 4.43Å; A185-L190 HydrophobicContact CB-CD2 3.86Å; A185-L190 HydrophobicContact CB-CG 3.95Å
186H97.9Very high96.1Very high0 Ų026.7 Ų26.70%014%0.144CC..  trans-121.3171.9-170.1-53.1-88.2000112.4H11 S58 R62 L87 E89 S189 L190H11-H186 AromaticContact CD2-CE1 3.6Å; H11-H186 AromaticContact CD2-CG 3.82Å; H11-H186 AromaticContact CD2-ND1 2.99Å; H11-H186 PolarHBondContact CD2-ND1 3.47Å; H11-H186 AromaticContact NE2-CE1 3.82Å; H11-H186 AromaticContact NE2-CG 3.99Å; H11-H186 AromaticContact NE2-ND1 3Å; H11-H186 PolarHBondContact NE2-ND1 3.16Å; S58-H186 WeakPolarHBondContact CB-NE2 3.16Å; S58-H186 PolarHBondContact OG-NE2 2.78Å; R62-H186 PolarHBondContact NE-CE1 2.96Å; R62-H186 PolarHBondContact NE-ND1 2.89Å; L87-H186 PolarHBondContact O-CD2 3.19Å; L87-H186 VanDerWaalsContact O-CD2 3.28Å; E89-H186 HydrophobicContact CB-CB 3.69Å; E89-H186 HydrophobicContact CG-CB 4.11Å; E89-H186 PolarHBondContact N-CD2 3.36Å; E89-H186 WeakPolarHBondContact OE2-CB 3.31Å; H186-S189 PolarHBondContact N-OG 2.85Å; H186-S189 VanDerWaalsContact N-OG 3.16Å; H186-S189 PolarHBondContact O-OG 2.8Å; H186-S189 VanDerWaalsContact O-OG 3.14Å; H186-L190 VanDerWaalsContact O-CB 3.27Å; H186-L190 WeakPolarHBondContact O-CB 3.33Å; H186-L190 WeakPolarHBondContact O-CG 3.28Å; H186-L190 PolarHBondContact O-N 2.97Å
187G93.6Very high95.9Very high4 Ų421.4 Ų21.44%0.04112%0.121CC..Hα-helixtrans-59.1-55-174.900000112.5E89 R191E89-G187 PolarHBondContact OE2-N 3.04Å; G187-R191 WeakPolarHBondContact O-CB 3.39Å; G187-R191 VanDerWaalsContact O-CG 3.24Å; G187-R191 WeakPolarHBondContact O-CG 3Å; G187-R191 PolarHBondContact O-N 3.37Å
188N92.9Very high95.8Very high4 Ų421.5 Ų21.52%0.02111%0.109CC..Hα-helixtrans-79.1-30.5-173.4-57-67.8000113.3E89 R90 Y92 L156 T159 R191 G192E89-N188 WeakPolarHBondContact OE1-CB 3.42Å; E89-N188 PolarHBondContact OE1-N 3.17Å; E89-N188 PolarHBondContact OE1-ND2 3.24Å; R90-N188 HydrophobicContact CB-CB 3.86Å; Y92-N188 PolarHBondContact OH-ND2 2.79Å; L156-N188 HydrophobicContact CD1-CB 3.94Å; T159-N188 HydrophobicContact CG2-CB 4.46Å; N188-R191 PolarHBondContact OD1-NH1 2.66Å; N188-G192 PolarHBondContact O-N 3.11Å; N188-G192 VanDerWaalsContact O-N 3.12Å
189S95.2Very high95.6Very high0 Ų022.4 Ų22.40%012%0.119CC..Hα-helixtrans-65.3-43.4173.560.20000111.5L87 N88 H186 G192 I193L87-S189 PolarHBondContact O-OG 3.26Å; N88-S189 WeakPolarHBondContact O-CB 3.41Å; H186-S189 PolarHBondContact N-OG 2.85Å; H186-S189 VanDerWaalsContact N-OG 3.16Å; H186-S189 PolarHBondContact O-OG 2.8Å; H186-S189 VanDerWaalsContact O-OG 3.14Å; S189-G192 PolarHBondContact O-N 3.05Å; S189-I193 PolarHBondContact O-N 3.36Å
190L96.6Very high95.4Very high0 Ų020.3 Ų20.30%011%0.111CC..Hα-helixtrans-71-38.7177.7-68.4-179.7000112.2M8 R10 I183 A185 H186 G192 I193 V194 L210M8-L190 HydrophobicContact CB-CD1 4.42Å; M8-L190 HydrophobicContact CB-CD2 4.05Å; M8-L190 HydrophobicContact CG-CD2 4.3Å; M8-L190 HydrophobicContact SD-CD2 3.84Å; R10-L190 HydrophobicContact CB-CD1 4.12Å; I183-L190 HydrophobicContact CG2-CD2 4.08Å; A185-L190 HydrophobicContact CB-CD1 4.43Å; A185-L190 HydrophobicContact CB-CD2 3.86Å; A185-L190 HydrophobicContact CB-CG 3.95Å; H186-L190 VanDerWaalsContact O-CB 3.27Å; H186-L190 WeakPolarHBondContact O-CB 3.33Å; H186-L190 WeakPolarHBondContact O-CG 3.28Å; H186-L190 PolarHBondContact O-N 2.97Å; L190-G192 PolarHBondContact O-N 3.06Å; L190-I193 HydrophobicContact CD2-CD1 4.29Å; L190-I193 PolarHBondContact O-N 3.18Å; L190-I193 VanDerWaalsContact O-N 3.08Å; L190-V194 WeakPolarHBondContact O-CG2 3.22Å; L190-V194 PolarHBondContact O-N 2.89Å; L190-L210 HydrophobicContact CB-CD1 3.53Å
191R92.9Very high95.2Very high26 Ų2620.1 Ų20.110%0.09812%0.12CC..Hα-helixtrans-51.5-39.6169-82.1171.6174.6168.7-8.3111.7G187 N188 V194 K195 I205 L208 N209 L210G187-R191 WeakPolarHBondContact O-CB 3.39Å; G187-R191 VanDerWaalsContact O-CG 3.24Å; G187-R191 WeakPolarHBondContact O-CG 3Å; G187-R191 PolarHBondContact O-N 3.37Å; N188-R191 PolarHBondContact OD1-NH1 2.66Å; R191-V194 PolarHBondContact O-N 3.25Å; R191-K195 WeakPolarHBondContact O-CB 3.26Å; R191-K195 PolarHBondContact O-N 3.5Å; R191-I205 HydrophobicContact CB-CD1 3.85Å; R191-I205 HydrophobicContact CB-CG1 4.17Å; R191-I205 HydrophobicContact CG-CD1 4.15Å; R191-I205 VanDerWaalsContact O-CD1 3.26Å; R191-I205 WeakPolarHBondContact O-CD1 3.22Å; R191-L208 HydrophobicContact CG-CD2 4.36Å; R191-L208 PolarHBondContact NE-O 3.04Å; R191-L208 PolarHBondContact NH2-O 3.15Å; R191-N209 VanDerWaalsContact NH2-CG 3.29Å; R191-N209 PolarHBondContact NH2-OD1 3.21Å; R191-L210 HydrophobicContact CG-CD1 4.3Å; R191-L210 HydrophobicContact CG-CG 4.44Å
192G91.8Very high94.9Very high1 Ų123.5 Ų23.51%0.0114%0.138CC..Hα-helixtrans-61-45.2176.800000114.4N188 S189 L190 H196N188-G192 PolarHBondContact O-N 3.11Å; N188-G192 VanDerWaalsContact O-N 3.12Å; S189-G192 PolarHBondContact O-N 3.05Å; L190-G192 PolarHBondContact O-N 3.06Å; G192-H196 PolarHBondContact O-N 2.81Å
193I94.9Very high94.4Very high1 Ų130.6 Ų30.61%0.00517%0.171CC..Hα-helixtrans-65.4-45175.8-61.3172.6000110.2M8 L87 W167 I183 S189 L190 K195 H196 L197M8-I193 HydrophobicContact CE-CG2 4.38Å; M8-I193 HydrophobicContact SD-CB 4.25Å; M8-I193 HydrophobicContact SD-CD1 4.43Å; M8-I193 HydrophobicContact SD-CG2 3.79Å; L87-I193 HydrophobicContact CD2-CD1 4.15Å; W167-I193 HydrophobicContact CD2-CG2 4.12Å; W167-I193 HydrophobicContact CE3-CD1 4.21Å; W167-I193 HydrophobicContact CE3-CG1 4.37Å; W167-I193 HydrophobicContact CE3-CG2 3.67Å; W167-I193 HydrophobicContact CH2-CG2 4.17Å; W167-I193 HydrophobicContact CZ3-CG2 3.69Å; I183-I193 HydrophobicContact CD1-CD1 4.26Å; S189-I193 PolarHBondContact O-N 3.36Å; L190-I193 HydrophobicContact CD2-CD1 4.29Å; L190-I193 PolarHBondContact O-N 3.18Å; L190-I193 VanDerWaalsContact O-N 3.08Å; I193-K195 PolarHBondContact O-N 3.4Å; I193-H196 PolarHBondContact O-N 3.19Å; I193-L197 HydrophobicContact CG2-CD1 3.87Å; I193-L197 HydrophobicContact CG2-CG 4.25Å; I193-L197 WeakPolarHBondContact O-CG 3.29Å; I193-L197 PolarHBondContact O-N 3.2Å
194V95.3Very high93.9Very high0 Ų032.4 Ų32.40%019%0.186CC..Hα-helixtrans-59.5-46.6177.5171.40000111.5M8 L190 R191 H196 L197 E198 M200 L208 Y218 M230M8-V194 HydrophobicContact CE-CG2 3.81Å; L190-V194 WeakPolarHBondContact O-CG2 3.22Å; L190-V194 PolarHBondContact O-N 2.89Å; R191-V194 PolarHBondContact O-N 3.25Å; V194-H196 PolarHBondContact O-N 2.8Å; V194-L197 PolarHBondContact O-N 2.9Å; V194-E198 WeakPolarHBondContact O-CB 3.49Å; V194-E198 PolarHBondContact O-N 3.39Å; V194-M200 HydrophobicContact CG1-SD 3.9Å; V194-L208 HydrophobicContact CB-CD2 4.13Å; V194-L208 HydrophobicContact CG1-CD2 3.53Å; V194-Y218 WeakPolarHBondContact CG1-OH 3.46Å; V194-Y218 HydrophobicContact CG2-CE2 4.32Å; V194-M230 HydrophobicContact CG1-CE 3.88Å
195K94.1Very high93.4Very high36 Ų3632.4 Ų32.416%0.15719%0.186CC..Hα-helixtrans-53.9-42.7177-169.5-169.2-166.6-67.40111.4F119 I160 R191 I193 G199 M200 D202 I205F119-K195 HydrophobicContact CE2-CD 3.94Å; F119-K195 VanDerWaalsContact CE2-CE 3.48Å; I160-K195 HydrophobicContact CD1-CD 3.78Å; R191-K195 WeakPolarHBondContact O-CB 3.26Å; R191-K195 PolarHBondContact O-N 3.5Å; I193-K195 PolarHBondContact O-N 3.4Å; K195-G199 WeakPolarHBondContact O-CA 3.44Å; K195-G199 PolarHBondContact O-N 3.41Å; K195-M200 HydrophobicContact CG-CB 4.02Å; K195-M200 WeakPolarHBondContact CG-O 3.27Å; K195-M200 PolarHBondContact NZ-O 2.77Å; K195-M200 PolarHBondContact O-N 2.96Å; K195-D202 WeakPolarHBondContact CE-OD1 3.47Å; K195-D202 IonicContact NZ-OD1 2.81Å; K195-D202 PolarHBondContact NZ-OD1 3.3Å; K195-I205 HydrophobicContact CB-CB 4.37Å; K195-I205 HydrophobicContact CB-CD1 3.91Å; K195-I205 HydrophobicContact CB-CG1 3.95Å; K195-I205 HydrophobicContact CD-CB 4.24Å; K195-I205 HydrophobicContact CD-CG1 4.34Å; K195-I205 HydrophobicContact CD-CG2 3.94Å; K195-I205 HydrophobicContact CG-CB 4.11Å; K195-I205 HydrophobicContact CG-CG1 4.2Å; K195-I205 HydrophobicContact CG-CG2 4.34Å
196H92.6Very high92.8Very high88 Ų8834.8 Ų34.841%0.40720%0.198SC..Hα-helixtrans-71.3-46.4-180178.271.6000112.4L164 W167 G192 I193 V194 E198 G199L164-H196 HydrophobicContact CD2-CB 3.65Å; W167-H196 AromaticContact CD1-CD2 3.89Å; W167-H196 AromaticContact NE1-CD2 3.53Å; W167-H196 AromaticContact NE1-NE2 3.76Å; G192-H196 PolarHBondContact O-N 2.81Å; I193-H196 PolarHBondContact O-N 3.19Å; V194-H196 PolarHBondContact O-N 2.8Å; H196-E198 PolarHBondContact O-N 2.72Å; H196-G199 PolarHBondContact O-N 3.22Å
197L92.9Very high92.2Very high14 Ų1440.4 Ų40.47%0.07322%0.224CC..Hα-helixtrans-61.3-44.2178.8-75.2175.4000112.4L6 M8 W167 I193 V194 Y218 L220 L224 P226L6-L197 HydrophobicContact CD2-CD1 4.13Å; M8-L197 HydrophobicContact CE-CD1 4.37Å; W167-L197 HydrophobicContact CH2-CD1 4.26Å; W167-L197 HydrophobicContact CH2-CD2 4.04Å; W167-L197 HydrophobicContact CH2-CG 4.45Å; W167-L197 HydrophobicContact CZ2-CD2 3.6Å; W167-L197 HydrophobicContact CZ2-CG 4.23Å; I193-L197 HydrophobicContact CG2-CD1 3.87Å; I193-L197 HydrophobicContact CG2-CG 4.25Å; I193-L197 WeakPolarHBondContact O-CG 3.29Å; I193-L197 PolarHBondContact O-N 3.2Å; V194-L197 PolarHBondContact O-N 2.9Å; L197-Y218 HydrophobicContact CD1-CD2 4.42Å; L197-Y218 HydrophobicContact CD1-CE2 4.45Å; L197-Y218 HydrophobicContact CD1-CG 4.45Å; L197-L220 HydrophobicContact CD2-CD1 4.34Å; L197-L220 HydrophobicContact CD2-CD2 4.15Å; L197-L224 WeakPolarHBondContact CD2-O 3.33Å; L197-P226 HydrophobicContact CB-CG 4.17Å; L197-P226 WeakPolarHBondContact O-CD 3.22Å
198E93.8Very high91.9Very high77 Ų7741.8 Ų41.836%0.3623%0.231SC..Hα-helixtrans-92.6-2.3-175.3-69.9-172.2-162.300113.8V194 H196 M200 Y218 P226 M230V194-E198 WeakPolarHBondContact O-CB 3.49Å; V194-E198 PolarHBondContact O-N 3.39Å; H196-E198 PolarHBondContact O-N 2.72Å; E198-M200 VanDerWaalsContact C-N 3.26Å; E198-M200 HydrophobicContact CB-CG 3.76Å; E198-M200 HydrophobicContact CB-SD 4.47Å; E198-M200 PolarHBondContact O-N 2.92Å; E198-Y218 HydrophobicContact CG-CE1 4.19Å; E198-Y218 VanDerWaalsContact OE1-CE1 3.31Å; E198-Y218 WeakPolarHBondContact OE1-CE1 3.45Å; E198-Y218 PolarHBondContact OE1-OH 2.86Å; E198-P226 HydrophobicContact CG-CG 4.09Å; E198-M230 VanDerWaalsContact OE1-CE 3.32Å; E198-M230 WeakPolarHBondContact OE1-CE 3.45Å
199G92.7Very high91.6Very high68 Ų6842.6 Ų42.670%0.70124%0.235SC*.THydrogen-bonded Turntrans60.635.1-177.200000113.1K195 H196K195-G199 WeakPolarHBondContact O-CA 3.44Å; K195-G199 PolarHBondContact O-N 3.41Å; H196-G199 PolarHBondContact O-N 3.22Å
200M93.3Very high91.3Very high34 Ų3442.7 Ų42.717%0.16724%0.235CC..  trans-69.7144.3-174.8-59.1178.577.800112.1V194 K195 E198 A204 I205 L208V194-M200 HydrophobicContact CG1-SD 3.9Å; K195-M200 HydrophobicContact CG-CB 4.02Å; K195-M200 WeakPolarHBondContact CG-O 3.27Å; K195-M200 PolarHBondContact NZ-O 2.77Å; K195-M200 PolarHBondContact O-N 2.96Å; E198-M200 VanDerWaalsContact C-N 3.26Å; E198-M200 HydrophobicContact CB-CG 3.76Å; E198-M200 HydrophobicContact CB-SD 4.47Å; E198-M200 PolarHBondContact O-N 2.92Å; M200-A204 HydrophobicContact CB-CB 4.34Å; M200-A204 HydrophobicContact CE-CB 3.76Å; M200-I205 HydrophobicContact CE-CD1 4.47Å; M200-I205 HydrophobicContact SD-CD1 3.88Å; M200-L208 HydrophobicContact CE-CB 4.3Å; M200-L208 HydrophobicContact SD-CD2 4.25Å
201S94.5Very high91.1Very high68 Ų6842.8 Ų42.848%0.47624%0.236SC..  trans-65.9160.7168.871.90000111.6Q203 A204 I205S201-Q203 PolarHBondContact O-N 3.19Å; S201-A204 PolarHBondContact O-N 2.89Å; S201-A204 WeakPolarHBondContact OG-CB 3.43Å; S201-A204 PolarHBondContact OG-N 3.12Å; S201-A204 VanDerWaalsContact OG-N 3.13Å; S201-I205 PolarHBondContact O-N 3.39Å; S201-I205 VanDerWaalsContact O-N 3.15Å
202D91.8Very high91.2Very high72 Ų7243 Ų4339%0.38524%0.24SC..Hα-helixtrans-61.9-34.2177.2-62.9-6.9000110.9F119 K195 I205 M206F119-D202 HydrophobicContact CB-CB 4.23Å; F119-D202 HydrophobicContact CD1-CB 3.92Å; F119-D202 VanDerWaalsContact CD1-CG 3.47Å; F119-D202 WeakPolarHBondContact CD1-OD2 3.49Å; F119-D202 HydrophobicContact CD2-CB 4.29Å; F119-D202 HydrophobicContact CE1-CB 4.36Å; F119-D202 VanDerWaalsContact CE1-CG 3.44Å; F119-D202 VanDerWaalsContact CE1-OD2 3.27Å; F119-D202 WeakPolarHBondContact CE1-OD2 3.2Å; F119-D202 HydrophobicContact CG-CB 3.88Å; K195-D202 WeakPolarHBondContact CE-OD1 3.47Å; K195-D202 IonicContact NZ-OD1 2.81Å; K195-D202 PolarHBondContact NZ-OD1 3.3Å; D202-I205 VanDerWaalsContact O-CG2 3.23Å; D202-I205 WeakPolarHBondContact O-CG2 3.43Å; D202-M206 VanDerWaalsContact O-CG 3.29Å; D202-M206 WeakPolarHBondContact O-CG 3.37Å
203Q88.5Confident91.4Very high149 Ų14943 Ų4370%0.69624%0.24SC*.Hα-helixtrans-68.2-45.2174.8-170.2177.34.300112.6S201 I205 M206S201-Q203 PolarHBondContact O-N 3.19Å; Q203-I205 VanDerWaalsContact C-N 3.32Å; Q203-I205 PolarHBondContact O-N 3.14Å; Q203-M206 HydrophobicContact CB-CE 4.47Å; Q203-M206 PolarHBondContact O-N 2.86Å
204A89.2Confident91.5Very high38 Ų3843.1 Ų43.131%0.31424%0.241SC..Hα-helixtrans-64.4-37.7-177.400000111.9M200 S201 M206 E207 L208M200-A204 HydrophobicContact CB-CB 4.34Å; M200-A204 HydrophobicContact CE-CB 3.76Å; S201-A204 PolarHBondContact O-N 2.89Å; S201-A204 WeakPolarHBondContact OG-CB 3.43Å; S201-A204 PolarHBondContact OG-N 3.12Å; S201-A204 VanDerWaalsContact OG-N 3.13Å; A204-M206 VanDerWaalsContact C-N 3.29Å; A204-M206 PolarHBondContact O-N 3.22Å; A204-E207 PolarHBondContact O-N 2.85Å; A204-L208 PolarHBondContact O-N 3.01Å
205I89.1Confident91.6Very high0 Ų043.1 Ų43.10%024%0.241CC..Hα-helixtrans-69.8-26.3-179.4-166.661.9000113.2F119 L156 R191 K195 M200 S201 D202 Q203 E207 L208F119-I205 HydrophobicContact CD2-CG2 4.13Å; L156-I205 HydrophobicContact CD2-CG1 4.18Å; L156-I205 HydrophobicContact CD2-CG2 4.05Å; R191-I205 HydrophobicContact CB-CD1 3.85Å; R191-I205 HydrophobicContact CB-CG1 4.17Å; R191-I205 HydrophobicContact CG-CD1 4.15Å; R191-I205 VanDerWaalsContact O-CD1 3.26Å; R191-I205 WeakPolarHBondContact O-CD1 3.22Å; K195-I205 HydrophobicContact CB-CB 4.37Å; K195-I205 HydrophobicContact CB-CD1 3.91Å; K195-I205 HydrophobicContact CB-CG1 3.95Å; K195-I205 HydrophobicContact CD-CB 4.24Å; K195-I205 HydrophobicContact CD-CG1 4.34Å; K195-I205 HydrophobicContact CD-CG2 3.94Å; K195-I205 HydrophobicContact CG-CB 4.11Å; K195-I205 HydrophobicContact CG-CG1 4.2Å; K195-I205 HydrophobicContact CG-CG2 4.34Å; M200-I205 HydrophobicContact CE-CD1 4.47Å; M200-I205 HydrophobicContact SD-CD1 3.88Å; S201-I205 PolarHBondContact O-N 3.39Å; S201-I205 VanDerWaalsContact O-N 3.15Å; D202-I205 VanDerWaalsContact O-CG2 3.23Å; D202-I205 WeakPolarHBondContact O-CG2 3.43Å; Q203-I205 VanDerWaalsContact C-N 3.32Å; Q203-I205 PolarHBondContact O-N 3.14Å; I205-E207 PolarHBondContact O-N 3.23Å; I205-L208 HydrophobicContact CD1-CB 4.2Å; I205-L208 HydrophobicContact CD1-CD2 3.69Å; I205-L208 PolarHBondContact O-N 3Å
206M85.6Confident91.8Very high51 Ų5141.4 Ų41.425%0.25123%0.234SC..Hα-helixtrans-67.4-27.2176.6-66-167.9-72.900112.6R117 F119 D202 Q203 A204R117-M206 WeakPolarHBondContact O-CG 3.38Å; F119-M206 HydrophobicContact CB-SD 4.38Å; D202-M206 VanDerWaalsContact O-CG 3.29Å; D202-M206 WeakPolarHBondContact O-CG 3.37Å; Q203-M206 HydrophobicContact CB-CE 4.47Å; Q203-M206 PolarHBondContact O-N 2.86Å; A204-M206 VanDerWaalsContact C-N 3.29Å; A204-M206 PolarHBondContact O-N 3.22Å
207E85.6Confident92.1Very high117 Ų11737.4 Ų37.455%0.54722%0.215SC..Hα-helixtrans-90.8-22.6179.9-63.3-52.6143.800113.3R117 A204 I205 N209R117-E207 IonicContact NH1-OE1 3.04Å; R117-E207 IonicContact NH1-OE2 3.33Å; R117-E207 PolarHBondContact NH1-OE2 3Å; R117-E207 VanDerWaalsContact NH1-OE2 3.12Å; A204-E207 PolarHBondContact O-N 2.85Å; I205-E207 PolarHBondContact O-N 3.23Å; E207-N209 PolarHBondContact O-N 3.42Å; E207-N209 PolarHBondContact O-ND2 2.87Å
208L87.3Confident92.3Very high34 Ų3436.8 Ų36.818%0.17821%0.212CC..  trans-64.3120.1176.7179.167.6000110.2R191 V194 M200 A204 I205 L210 M230R191-L208 HydrophobicContact CG-CD2 4.36Å; R191-L208 PolarHBondContact NE-O 3.04Å; R191-L208 PolarHBondContact NH2-O 3.15Å; V194-L208 HydrophobicContact CB-CD2 4.13Å; V194-L208 HydrophobicContact CG1-CD2 3.53Å; M200-L208 HydrophobicContact CE-CB 4.3Å; M200-L208 HydrophobicContact SD-CD2 4.25Å; A204-L208 PolarHBondContact O-N 3.01Å; I205-L208 HydrophobicContact CD1-CB 4.2Å; I205-L208 HydrophobicContact CD1-CD2 3.69Å; I205-L208 PolarHBondContact O-N 3Å; L208-L210 HydrophobicContact CD1-CD2 4.22Å; L208-L210 HydrophobicContact CD2-CD2 4.08Å; L208-L210 HydrophobicContact CG-CD2 4.14Å; L208-M230 HydrophobicContact CD1-CE 4.22Å
209N85.1Confident92.4Very high21 Ų2136 Ų3611%0.11221%0.208CC..  trans-114131169.9-69.8-82.9000108.5R191 E207 V246R191-N209 VanDerWaalsContact NH2-CG 3.29Å; R191-N209 PolarHBondContact NH2-OD1 3.21Å; E207-N209 PolarHBondContact O-N 3.42Å; E207-N209 PolarHBondContact O-ND2 2.87Å; N209-V246 HydrophobicContact CB-CB 4.19Å; N209-V246 HydrophobicContact CB-CG1 3.35Å; N209-V246 HydrophobicContact CB-CG2 4.32Å; N209-V246 WeakPolarHBondContact O-CG1 2.97Å
210L90.3Very high92.6Very high1 Ų132.7 Ų32.71%0.00518%0.175CC..PPolyproline II helixtrans-97.7126.3178.6-61.9179.4000109.4R10 L190 R191 L208 I216 M230R10-L210 WeakPolarHBondContact CD-O 3.41Å; R10-L210 PolarHBondContact NH1-O 3.16Å; L190-L210 HydrophobicContact CB-CD1 3.53Å; R191-L210 HydrophobicContact CG-CD1 4.3Å; R191-L210 HydrophobicContact CG-CG 4.44Å; L208-L210 HydrophobicContact CD1-CD2 4.22Å; L208-L210 HydrophobicContact CD2-CD2 4.08Å; L208-L210 HydrophobicContact CG-CD2 4.14Å; L210-I216 HydrophobicContact CB-CD1 4.44Å; L210-I216 HydrophobicContact CD1-CD1 4.26Å; L210-I216 HydrophobicContact CD2-CD1 3.81Å; L210-I216 HydrophobicContact CG-CD1 4.39Å; L210-M230 HydrophobicContact CD2-SD 4.36Å
211P92.7Very high92.7Very high3 Ų333 Ų332%0.01918%0.177CC..PPolyproline II helixtrans-64.2153.1178.726.9-34.2000111.8R10 I214 F232 A242 V246R10-P211 WeakPolarHBondContact CB-O 3.34Å; P211-I214 HydrophobicContact CB-CB 4.34Å; P211-I214 HydrophobicContact CB-CD1 4.04Å; P211-I214 HydrophobicContact CB-CG1 4.33Å; P211-I214 HydrophobicContact CG-CB 4.01Å; P211-I214 HydrophobicContact CG-CD1 4.22Å; P211-I214 HydrophobicContact CG-CG1 4.46Å; P211-I214 HydrophobicContact CG-CG2 4.43Å; P211-F232 HydrophobicContact CG-CD1 4.01Å; P211-F232 HydrophobicContact CG-CE1 3.72Å; P211-F232 HydrophobicContact CG-CZ 4.4Å; P211-A242 HydrophobicContact CB-CB 3.82Å; P211-V246 HydrophobicContact CB-CG2 3.94Å
212T94.2Very high92.6Very high30 Ų3036 Ų3618%0.18418%0.182CC..SBendtrans-80.8138.9175.948.10000111R10 H11 E37 I214R10-T212 HydrophobicContact CG-CG2 4.41Å; R10-T212 VanDerWaalsContact CZ-CG2 3.45Å; H11-T212 WeakPolarHBondContact O-CB 3.2Å; H11-T212 WeakPolarHBondContact O-CG2 3.32Å; E37-T212 PolarHBondContact OE1-OG1 3.1Å; E37-T212 WeakPolarHBondContact OE2-CB 3.36Å; E37-T212 PolarHBondContact OE2-OG1 3.24Å; E37-T212 VanDerWaalsContact OE2-OG1 3.05Å; T212-I214 PolarHBondContact O-N 2.77Å
213G96Very high92.7Very high1 Ų138.6 Ų38.61%0.0119%0.191CC..SBendtrans67.7017300000116.8R10R10-G213 WeakPolarHBondContact O-CA 3.43Å; R10-G213 PolarHBondContact O-N 3.01Å
214I97.2Very high92.9Very high4 Ų432.3 Ų32.32%0.02116%0.162CC..  trans-93.4122.2177.1-63.3-171000109.6P211 T212 F232 T238 A242P211-I214 HydrophobicContact CB-CB 4.34Å; P211-I214 HydrophobicContact CB-CD1 4.04Å; P211-I214 HydrophobicContact CB-CG1 4.33Å; P211-I214 HydrophobicContact CG-CB 4.01Å; P211-I214 HydrophobicContact CG-CD1 4.22Å; P211-I214 HydrophobicContact CG-CG1 4.46Å; P211-I214 HydrophobicContact CG-CG2 4.43Å; T212-I214 PolarHBondContact O-N 2.77Å; I214-F232 HydrophobicContact CG2-CB 3.75Å; I214-F232 HydrophobicContact CG2-CD1 3.82Å; I214-F232 HydrophobicContact CG2-CG 4.18Å; I214-T238 HydrophobicContact CD1-CG2 4.15Å; I214-A242 HydrophobicContact CD1-CB 3.18Å; I214-A242 HydrophobicContact CG1-CB 4.38Å
215P98.2Very high93.2Very high0 Ų036.9 Ų36.90%018%0.175CC..EExtended strand (participates in β ladder)trans-65.1134.3172.9-15.727.9000112.4V7 V9 I45 F232 L233V7-P215 HydrophobicContact CG1-CB 3.93Å; V9-P215 HydrophobicContact CG2-CB 3.82Å; V9-P215 HydrophobicContact CG2-CG 4.13Å; I45-P215 HydrophobicContact CD1-CB 4.07Å; I45-P215 HydrophobicContact CD1-CG 3.78Å; I45-P215 HydrophobicContact CG1-CB 4.03Å; I45-P215 HydrophobicContact CG1-CG 3.72Å; P215-F232 WeakPolarHBondContact O-CA 3.46Å; P215-L233 HydrophobicContact CB-CB 4.09Å; P215-L233 HydrophobicContact CB-CD1 4.11Å; P215-L233 HydrophobicContact CB-CG 4.36Å; P215-L233 HydrophobicContact CG-CB 4.24Å; P215-L233 PolarHBondContact O-N 2.95Å
216I97.6Very high93.5Very high0 Ų038.6 Ų38.60%019%0.186CC..EExtended strand (participates in β ladder)trans-110.3121.4179.2-51.3170.2000107.5V7 M8 L210 Y218 M230 Q231 F232V7-I216 CarbonylContact C-O 3.53Å; V7-I216 VanDerWaalsContact CA-O 3.32Å; V7-I216 WeakPolarHBondContact CA-O 3.46Å; M8-I216 PolarHBondContact N-O 2.9Å; M8-I216 WeakPolarHBondContact O-CA 3.35Å; M8-I216 WeakPolarHBondContact O-CB 3.46Å; M8-I216 PolarHBondContact O-N 3.48Å; L210-I216 HydrophobicContact CB-CD1 4.44Å; L210-I216 HydrophobicContact CD1-CD1 4.26Å; L210-I216 HydrophobicContact CD2-CD1 3.81Å; L210-I216 HydrophobicContact CG-CD1 4.39Å; I216-Y218 HydrophobicContact CG2-CD2 4.31Å; I216-Y218 HydrophobicContact CG2-CE2 3.95Å; I216-M230 HydrophobicContact CG2-CB 3.8Å; I216-M230 HydrophobicContact CG2-CG 4.04Å; I216-M230 HydrophobicContact CG2-SD 3.78Å; I216-Q231 CarbonylContact C-O 3.58Å; I216-Q231 WeakPolarHBondContact CA-O 3.29Å; I216-F232 HydrophobicContact CD1-CE1 4.17Å; I216-F232 HydrophobicContact CG1-CD1 3.9Å; I216-F232 HydrophobicContact CG1-CE1 3.75Å
217V97.8Very high94Very high3 Ų339.8 Ų39.82%0.01820%0.196CC..EExtended strand (participates in β ladder)trans-106.4128.8-177-174.40000109.2R5 V7 M50 Q231 L233R5-V217 HydrophobicContact CG-CG1 3.92Å; V7-V217 HydrophobicContact CG2-CG2 4.23Å; M50-V217 HydrophobicContact CE-CG1 4.22Å; M50-V217 HydrophobicContact CE-CG2 3.83Å; M50-V217 HydrophobicContact SD-CG2 4.27Å; V217-Q231 HydrophobicContact CB-CB 4.39Å; V217-Q231 PolarHBondContact N-O 3.03Å; V217-Q231 PolarHBondContact O-N 3.21Å; V217-L233 HydrophobicContact CG2-CD1 3.57Å; V217-L233 HydrophobicContact CG2-CD2 3.87Å; V217-L233 HydrophobicContact CG2-CG 3.49Å; V217-L233 VanDerWaalsContact CG2-CG 3.49Å
218Y97.7Very high94.4Very high1 Ų137.2 Ų37.20%0.00418%0.183CC..EExtended strand (participates in β ladder)trans-111.6136.9167.4-82.8-86.6000110.5R5 L6 M8 V194 L197 E198 I216 L220 P226 M230R5-Y218 WeakPolarHBondContact CA-O 3.32Å; L6-Y218 PolarHBondContact N-O 3.25Å; L6-Y218 PolarHBondContact O-N 3.46Å; M8-Y218 HydrophobicContact CE-CD2 3.65Å; M8-Y218 HydrophobicContact CE-CE2 3.36Å; V194-Y218 WeakPolarHBondContact CG1-OH 3.46Å; V194-Y218 HydrophobicContact CG2-CE2 4.32Å; L197-Y218 HydrophobicContact CD1-CD2 4.42Å; L197-Y218 HydrophobicContact CD1-CE2 4.45Å; L197-Y218 HydrophobicContact CD1-CG 4.45Å; E198-Y218 HydrophobicContact CG-CE1 4.19Å; E198-Y218 VanDerWaalsContact OE1-CE1 3.31Å; E198-Y218 WeakPolarHBondContact OE1-CE1 3.45Å; E198-Y218 PolarHBondContact OE1-OH 2.86Å; I216-Y218 HydrophobicContact CG2-CD2 4.31Å; I216-Y218 HydrophobicContact CG2-CE2 3.95Å; Y218-L220 HydrophobicContact CD1-CD2 4.21Å; Y218-L220 HydrophobicContact CG-CD2 4.4Å; Y218-P226 HydrophobicContact CD1-CB 3.99Å; Y218-P226 HydrophobicContact CD1-CG 3.78Å; Y218-P226 HydrophobicContact CE1-CB 4.17Å; Y218-P226 HydrophobicContact CE1-CG 3.78Å; Y218-M230 HydrophobicContact CD1-CB 4.5Å; Y218-M230 HydrophobicContact CD2-CB 4.43Å; Y218-M230 HydrophobicContact CE1-CB 3.89Å; Y218-M230 HydrophobicContact CE2-CB 3.81Å; Y218-M230 VanDerWaalsContact OH-CE 3.24Å; Y218-M230 WeakPolarHBondContact OH-CE 3.26Å
219E96.4Very high94.6Very high60 Ų6040.6 Ų40.628%0.2821%0.207SC..EExtended strand (participates in β ladder)trans-104123.8161.3-80.4-179.6-16200108.5T3 H4 P226 T227 K228T3-E219 HydrophobicContact CG2-CB 3.58Å; T3-E219 HydrophobicContact CG2-CG 3.83Å; H4-E219 WeakPolarHBondContact O-CA 3.35Å; E219-P226 CarbonylContact O-C 3.57Å; E219-P226 VanDerWaalsContact O-CA 3.31Å; E219-P226 WeakPolarHBondContact O-CA 3.21Å; E219-T227 WeakPolarHBondContact CB-OG1 3.46Å; E219-T227 PolarHBondContact O-N 3.34Å; E219-T227 PolarHBondContact O-OG1 2.9Å; E219-K228 HydrophobicContact CB-CG 4.36Å; E219-K228 WeakPolarHBondContact OE1-CE 3.31Å; E219-K228 IonicContact OE1-NZ 2.6Å; E219-K228 PolarHBondContact OE1-NZ 3.11Å; E219-K228 WeakPolarHBondContact OE2-CE 3.38Å; E219-K228 IonicContact OE2-NZ 3Å; E219-K228 PolarHBondContact OE2-NZ 3.33Å
220L96.8Very high95Very high0 Ų041 Ų410%021%0.209CC..EExtended strand (participates in β ladder)trans-119.7139-172.3-53.8177.5000110.1T3 H4 L6 L197 Y218 L224 K225 P226T3-L220 CarbonylContact C-O 3.53Å; T3-L220 WeakPolarHBondContact CA-O 3.35Å; H4-L220 HydrophobicContact CB-CB 4.36Å; H4-L220 PolarHBondContact N-O 3.35Å; H4-L220 PolarHBondContact O-N 2.82Å; L6-L220 HydrophobicContact CB-CD1 4.3Å; L6-L220 HydrophobicContact CD2-CD1 4.5Å; L197-L220 HydrophobicContact CD2-CD1 4.34Å; L197-L220 HydrophobicContact CD2-CD2 4.15Å; Y218-L220 HydrophobicContact CD1-CD2 4.21Å; Y218-L220 HydrophobicContact CG-CD2 4.4Å; L220-L224 HydrophobicContact CB-CD2 4.49Å; L220-L224 HydrophobicContact CD1-CD2 4.4Å; L220-K225 CarbonylContact C-O 3.53Å; L220-K225 WeakPolarHBondContact CA-O 3.48Å; L220-P226 HydrophobicContact CD2-CB 4.43Å; L220-P226 HydrophobicContact CD2-CG 4.01Å
221N95.3Very high95.2Very high39 Ų3945.1 Ų45.121%0.20923%0.228CC..  trans-75.7-176.2170.871.85.2000111.5E223 L224 K225 T227N221-E223 PolarHBondContact ND2-OE2 3.3Å; N221-E223 PolarHBondContact O-N 3.31Å; N221-E223 WeakPolarHBondContact OD1-CA 3.37Å; N221-E223 PolarHBondContact OD1-N 3.17Å; N221-E223 PolarHBondContact OD1-OE2 3.28Å; N221-L224 WeakPolarHBondContact O-CA 3.4Å; N221-L224 PolarHBondContact O-N 3.12Å; N221-L224 PolarHBondContact OD1-N 3.48Å; N221-L224 VanDerWaalsContact OD1-N 3.14Å; N221-K225 PolarHBondContact N-O 3.32Å; N221-K225 PolarHBondContact OD1-N 3.42Å; N221-K225 PolarHBondContact OD1-O 2.89Å; N221-T227 HydrophobicContact CB-CG2 3.86Å
222K93.3Very high95.3Very high133 Ų13347.4 Ų47.458%0.57824%0.238SC*.THydrogen-bonded Turntrans-61.8-27.3-179.7-68.3-178.6176.3-175.60113.3L224K222-L224 PolarHBondContact O-N 2.79Å
223E92.6Very high95.4Very high126 Ų12647.5 Ų47.559%0.58924%0.237SC*.THydrogen-bonded Turntrans-866.9175.6-57.770.6-145.500112.4N221 K225N221-E223 PolarHBondContact ND2-OE2 3.3Å; N221-E223 PolarHBondContact O-N 3.31Å; N221-E223 WeakPolarHBondContact OD1-CA 3.37Å; N221-E223 PolarHBondContact OD1-N 3.17Å; N221-E223 PolarHBondContact OD1-OE2 3.28Å; E223-K225 HydrophobicContact CB-CG 4.47Å; E223-K225 PolarHBondContact O-N 3.26Å
224L94Very high95.1Very high16 Ų1649.2 Ų49.28%0.08426%0.255CS..SBendtrans60.626.9-177.4-54.1-174000114.6V172 I175 K176 L197 L220 N221 K222V172-L224 HydrophobicContact CB-CD1 4.03Å; V172-L224 HydrophobicContact CG1-CD1 3.63Å; V172-L224 HydrophobicContact CG2-CD1 3.68Å; I175-L224 HydrophobicContact CB-CD2 4.31Å; I175-L224 HydrophobicContact CG2-CD2 3.54Å; K176-L224 HydrophobicContact CG-CD1 4.27Å; K176-L224 HydrophobicContact CG-CD2 4.4Å; K176-L224 HydrophobicContact CG-CG 4.48Å; L197-L224 WeakPolarHBondContact CD2-O 3.33Å; L220-L224 HydrophobicContact CB-CD2 4.49Å; L220-L224 HydrophobicContact CD1-CD2 4.4Å; N221-L224 WeakPolarHBondContact O-CA 3.4Å; N221-L224 PolarHBondContact O-N 3.12Å; N221-L224 PolarHBondContact OD1-N 3.48Å; N221-L224 VanDerWaalsContact OD1-N 3.14Å; K222-L224 PolarHBondContact O-N 2.79Å
225K94.7Very high94.7Very high135 Ų13552.8 Ų52.859%0.58727%0.274SS*.  trans-89.9137.7172-63.9-171.9176.8-176.50110.7L220 N221 E223 T227L220-K225 CarbonylContact C-O 3.53Å; L220-K225 WeakPolarHBondContact CA-O 3.48Å; N221-K225 PolarHBondContact N-O 3.32Å; N221-K225 PolarHBondContact OD1-N 3.42Å; N221-K225 PolarHBondContact OD1-O 2.89Å; E223-K225 HydrophobicContact CB-CG 4.47Å; E223-K225 PolarHBondContact O-N 3.26Å; K225-T227 PolarHBondContact O-N 3.44Å
226P95.9Very high94.1Very high36 Ų3661.2 Ų61.223%0.23431%0.313CS..BIsolated β-bridgetrans-54.4128.2172.3-26.535.9000111.9L197 E198 Y218 E219 L220L197-P226 HydrophobicContact CB-CG 4.17Å; L197-P226 WeakPolarHBondContact O-CD 3.22Å; E198-P226 HydrophobicContact CG-CG 4.09Å; Y218-P226 HydrophobicContact CD1-CB 3.99Å; Y218-P226 HydrophobicContact CD1-CG 3.78Å; Y218-P226 HydrophobicContact CE1-CB 4.17Å; Y218-P226 HydrophobicContact CE1-CG 3.78Å; E219-P226 CarbonylContact O-C 3.57Å; E219-P226 VanDerWaalsContact O-CA 3.31Å; E219-P226 WeakPolarHBondContact O-CA 3.21Å; L220-P226 HydrophobicContact CD2-CB 4.43Å; L220-P226 HydrophobicContact CD2-CG 4.01Å
227T95.4Very high93.7Very high76 Ų7666.1 Ų66.147%0.46634%0.336SS..SBendtrans-87.7-15.4175.453.20000112.5E219 N221 K225E219-T227 WeakPolarHBondContact CB-OG1 3.46Å; E219-T227 PolarHBondContact O-N 3.34Å; E219-T227 PolarHBondContact O-OG1 2.9Å; N221-T227 HydrophobicContact CB-CG2 3.86Å; K225-T227 PolarHBondContact O-N 3.44Å
228K94.3Very high93.1Very high62 Ų6267.3 Ų67.327%0.2734%0.343SS..SBendtrans-152.4165.517863.7-175.9-177.9-1690110E219 Q231E219-K228 HydrophobicContact CB-CG 4.36Å; E219-K228 WeakPolarHBondContact OE1-CE 3.31Å; E219-K228 IonicContact OE1-NZ 2.6Å; E219-K228 PolarHBondContact OE1-NZ 3.11Å; E219-K228 WeakPolarHBondContact OE2-CE 3.38Å; E219-K228 IonicContact OE2-NZ 3Å; E219-K228 PolarHBondContact OE2-NZ 3.33Å; K228-Q231 VanDerWaalsContact CE-CD 3.5Å; K228-Q231 VanDerWaalsContact NZ-OE1 3.14Å
229P92.1Very high92.5Very high105 Ų10568.5 Ų68.568%0.68235%0.351SS*.  trans-56.5150.5173.9-24.435000112.1Q231P229-Q231 PolarHBondContact O-N 3.23Å
230M93.6Very high92.1Very high31 Ų3171.5 Ų71.515%0.15336%0.36CS..  trans-55.4140174.379.8178.683.800110.7V194 E198 L208 L210 I216 Y218 F232V194-M230 HydrophobicContact CG1-CE 3.88Å; E198-M230 VanDerWaalsContact OE1-CE 3.32Å; E198-M230 WeakPolarHBondContact OE1-CE 3.45Å; L208-M230 HydrophobicContact CD1-CE 4.22Å; L210-M230 HydrophobicContact CD2-SD 4.36Å; I216-M230 HydrophobicContact CG2-CB 3.8Å; I216-M230 HydrophobicContact CG2-CG 4.04Å; I216-M230 HydrophobicContact CG2-SD 3.78Å; Y218-M230 HydrophobicContact CD1-CB 4.5Å; Y218-M230 HydrophobicContact CD2-CB 4.43Å; Y218-M230 HydrophobicContact CE1-CB 3.89Å; Y218-M230 HydrophobicContact CE2-CB 3.81Å; Y218-M230 VanDerWaalsContact OH-CE 3.24Å; Y218-M230 WeakPolarHBondContact OH-CE 3.26Å; M230-F232 HydrophobicContact CG-CZ 4.34Å; M230-F232 HydrophobicContact SD-CE1 4.37Å; M230-F232 HydrophobicContact SD-CZ 3.97Å
231Q94.3Very high91.6Very high87 Ų8776.7 Ų76.741%0.40738%0.382SS..EExtended strand (participates in β ladder)trans-113.6136.7-178.5-58.1-175.4-52.900110.2I216 V217 K228 P229I216-Q231 CarbonylContact C-O 3.58Å; I216-Q231 WeakPolarHBondContact CA-O 3.29Å; V217-Q231 HydrophobicContact CB-CB 4.39Å; V217-Q231 PolarHBondContact N-O 3.03Å; V217-Q231 PolarHBondContact O-N 3.21Å; K228-Q231 VanDerWaalsContact CE-CD 3.5Å; K228-Q231 VanDerWaalsContact NZ-OE1 3.14Å; P229-Q231 PolarHBondContact O-N 3.23Å
232F95.1Very high90.9Very high51 Ų5175.8 Ų75.822%0.22438%0.38CS..EExtended strand (participates in β ladder)trans-94.9129.4175.4-63.5-68.7000110P211 I214 P215 I216 M230 V239 M243P211-F232 HydrophobicContact CG-CD1 4.01Å; P211-F232 HydrophobicContact CG-CE1 3.72Å; P211-F232 HydrophobicContact CG-CZ 4.4Å; I214-F232 HydrophobicContact CG2-CB 3.75Å; I214-F232 HydrophobicContact CG2-CD1 3.82Å; I214-F232 HydrophobicContact CG2-CG 4.18Å; P215-F232 WeakPolarHBondContact O-CA 3.46Å; I216-F232 HydrophobicContact CD1-CE1 4.17Å; I216-F232 HydrophobicContact CG1-CD1 3.9Å; I216-F232 HydrophobicContact CG1-CE1 3.75Å; M230-F232 HydrophobicContact CG-CZ 4.34Å; M230-F232 HydrophobicContact SD-CE1 4.37Å; M230-F232 HydrophobicContact SD-CZ 3.97Å; F232-V239 HydrophobicContact CB-CG1 3.72Å; F232-V239 HydrophobicContact CB-CG2 4.04Å; F232-V239 HydrophobicContact CD2-CG1 4.24Å; F232-V239 HydrophobicContact CG-CG1 4.29Å; F232-M243 HydrophobicContact CD2-SD 4.07Å; F232-M243 HydrophobicContact CE2-CE 4.19Å; F232-M243 HydrophobicContact CE2-SD 3.49Å; F232-M243 WeakPolarHBondContact CE2-SD 3.42Å; F232-M243 HydrophobicContact CZ-SD 3.83Å
233L94.5Very high90.2Very high31 Ų3173.1 Ų73.116%0.16237%0.371CS..  trans-90.3132.5174.4-61.7-179.3000111.2A44 I45 A48 M50 P215 V217A44-L233 HydrophobicContact CB-CB 4.04Å; I45-L233 HydrophobicContact CG1-CD1 4.26Å; A48-L233 HydrophobicContact CB-CD1 4.4Å; M50-L233 HydrophobicContact CE-CD1 3.64Å; M50-L233 HydrophobicContact CE-CD2 4.08Å; M50-L233 HydrophobicContact CE-CG 4.43Å; M50-L233 HydrophobicContact SD-CD1 3.71Å; P215-L233 HydrophobicContact CB-CB 4.09Å; P215-L233 HydrophobicContact CB-CD1 4.11Å; P215-L233 HydrophobicContact CB-CG 4.36Å; P215-L233 HydrophobicContact CG-CB 4.24Å; P215-L233 PolarHBondContact O-N 2.95Å; V217-L233 HydrophobicContact CG2-CD1 3.57Å; V217-L233 HydrophobicContact CG2-CD2 3.87Å; V217-L233 HydrophobicContact CG2-CG 3.49Å; V217-L233 VanDerWaalsContact CG2-CG 3.49Å
234G91.4Very high89.7Confident37 Ų3771.7 Ų71.738%0.38136%0.364SS..SBendtrans155.6174.2177.900000110.1
235D88Confident89Confident79 Ų7973.5 Ų73.542%0.42238%0.381SS..  trans-64.7150.3166.263.894.6000110.3E237 T238 V239D235-E237 PolarHBondContact O-N 2.93Å; D235-E237 PolarHBondContact OD1-N 3.46Å; D235-T238 PolarHBondContact O-N 3.43Å; D235-T238 WeakPolarHBondContact OD1-CB 3.45Å; D235-T238 PolarHBondContact OD1-N 2.89Å; D235-T238 PolarHBondContact OD1-OG1 3.38Å; D235-T238 VanDerWaalsContact OD1-OG1 3.06Å; D235-T238 WeakPolarHBondContact OD2-CB 3.41Å; D235-T238 PolarHBondContact OD2-OG1 2.77Å; D235-V239 PolarHBondContact O-N 2.66Å
236E85.3Confident87.9Confident177 Ų17767.7 Ų67.783%0.82736%0.357SS*.Hα-helixtrans-56.1-37.6-174.7-67.8-174.7166.500112.4R240E236-R240 VanDerWaalsContact O-CB 3.22Å; E236-R240 WeakPolarHBondContact O-CB 3.45Å; E236-R240 PolarHBondContact O-N 2.93Å
237E88.6Confident86.6Confident103 Ų10368.9 Ų68.948%0.48137%0.37SS..Hα-helixtrans-68.3-44.7-179.1-168.3-177.6172.900111.6D235 R240 K241D235-E237 PolarHBondContact O-N 2.93Å; D235-E237 PolarHBondContact OD1-N 3.46Å; E237-R240 PolarHBondContact O-N 3.46Å; E237-K241 HydrophobicContact CG-CD 4.26Å; E237-K241 WeakPolarHBondContact O-CB 3.47Å; E237-K241 WeakPolarHBondContact O-CG 3.28Å; E237-K241 PolarHBondContact O-N 2.89Å; E237-K241 WeakPolarHBondContact OE1-CE 3.35Å; E237-K241 IonicContact OE1-NZ 3.94Å; E237-K241 PolarHBondContact OE1-NZ 2.86Å
238T85.8Confident85.5Confident28 Ų2867.9 Ų67.917%0.17237%0.37CS..Hα-helixtrans-59.2-48.3174.7-72.10000111.3R40 I214 D235 K241 A242R40-T238 VanDerWaalsContact NE-CG2 3.33Å; I214-T238 HydrophobicContact CD1-CG2 4.15Å; D235-T238 PolarHBondContact O-N 3.43Å; D235-T238 WeakPolarHBondContact OD1-CB 3.45Å; D235-T238 PolarHBondContact OD1-N 2.89Å; D235-T238 PolarHBondContact OD1-OG1 3.38Å; D235-T238 VanDerWaalsContact OD1-OG1 3.06Å; D235-T238 WeakPolarHBondContact OD2-CB 3.41Å; D235-T238 PolarHBondContact OD2-OG1 2.77Å; T238-K241 PolarHBondContact O-N 2.88Å; T238-A242 VanDerWaalsContact O-CB 3.28Å; T238-A242 WeakPolarHBondContact O-CB 3.37Å; T238-A242 PolarHBondContact O-N 3.42Å
239V85.7Confident83.9Confident26 Ų2669.2 Ų69.216%0.15838%0.377CS..Hα-helixtrans-63.2-46.4179.9175.10000110F232 D235 A242 M243F232-V239 HydrophobicContact CB-CG1 3.72Å; F232-V239 HydrophobicContact CB-CG2 4.04Å; F232-V239 HydrophobicContact CD2-CG1 4.24Å; F232-V239 HydrophobicContact CG-CG1 4.29Å; D235-V239 PolarHBondContact O-N 2.66Å; V239-A242 PolarHBondContact O-N 3.26Å; V239-M243 HydrophobicContact CG1-CG 4.35Å; V239-M243 WeakPolarHBondContact O-CB 3.5Å; V239-M243 VanDerWaalsContact O-CG 3.27Å; V239-M243 WeakPolarHBondContact O-CG 3.37Å; V239-M243 PolarHBondContact O-N 3.44Å
240R87.1Confident81.8Confident124 Ų12466.2 Ų66.247%0.46837%0.365SS..Hα-helixtrans-58.2-52.2177.4-175.1-174.666.490.5-2.8111.9E236 E237 A242 M243 E244E236-R240 VanDerWaalsContact O-CB 3.22Å; E236-R240 WeakPolarHBondContact O-CB 3.45Å; E236-R240 PolarHBondContact O-N 2.93Å; E237-R240 PolarHBondContact O-N 3.46Å; R240-A242 VanDerWaalsContact C-N 3.29Å; R240-A242 PolarHBondContact O-N 2.99Å; R240-M243 PolarHBondContact O-N 3.44Å; R240-E244 IonicContact CZ-OE1 3.35Å; R240-E244 VanDerWaalsContact NH1-CD 3.33Å; R240-E244 IonicContact NH1-OE1 3.08Å; R240-E244 PolarHBondContact NH1-OE1 3.49Å; R240-E244 IonicContact NH1-OE2 2.67Å; R240-E244 PolarHBondContact NH1-OE2 3.36Å; R240-E244 WeakPolarHBondContact O-CG 3.4Å; R240-E244 PolarHBondContact O-N 3.15Å
241K86.9Confident79.4Confident108 Ų10872.7 Ų72.747%0.4739%0.392SS..Hα-helixtrans-59.9-39.8179.6-76.9179.3-178.6168.10112E237 T238 E244 A245E237-K241 HydrophobicContact CG-CD 4.26Å; E237-K241 WeakPolarHBondContact O-CB 3.47Å; E237-K241 WeakPolarHBondContact O-CG 3.28Å; E237-K241 PolarHBondContact O-N 2.89Å; E237-K241 WeakPolarHBondContact OE1-CE 3.35Å; E237-K241 IonicContact OE1-NZ 3.94Å; E237-K241 PolarHBondContact OE1-NZ 2.86Å; T238-K241 PolarHBondContact O-N 2.88Å; K241-E244 PolarHBondContact O-N 2.98Å; K241-A245 WeakPolarHBondContact O-CB 3.05Å; K241-A245 PolarHBondContact O-N 2.89Å
242A79.9Confident76.9Confident21 Ų2172.4 Ų72.417%0.17441%0.405CS..Hα-helixtrans-68.9-39.4178.400000112P211 I214 T238 V239 R240 A245 V246P211-A242 HydrophobicContact CB-CB 3.82Å; I214-A242 HydrophobicContact CD1-CB 3.18Å; I214-A242 HydrophobicContact CG1-CB 4.38Å; T238-A242 VanDerWaalsContact O-CB 3.28Å; T238-A242 WeakPolarHBondContact O-CB 3.37Å; T238-A242 PolarHBondContact O-N 3.42Å; V239-A242 PolarHBondContact O-N 3.26Å; R240-A242 VanDerWaalsContact C-N 3.29Å; R240-A242 PolarHBondContact O-N 2.99Å; A242-A245 PolarHBondContact O-N 2.85Å; A242-V246 VanDerWaalsContact O-CB 3.22Å; A242-V246 WeakPolarHBondContact O-CB 3.3Å; A242-V246 WeakPolarHBondContact O-CG2 3.48Å; A242-V246 PolarHBondContact O-N 3.18Å
243M78.4Confident74.1Confident76 Ų7683 Ų8337%0.37445%0.45SS..Hα-helixtrans-64.4-39.6173.5-70.6-56.3-6300112.1F232 V239 R240 V246 A247F232-M243 HydrophobicContact CD2-SD 4.07Å; F232-M243 HydrophobicContact CE2-CE 4.19Å; F232-M243 HydrophobicContact CE2-SD 3.49Å; F232-M243 WeakPolarHBondContact CE2-SD 3.42Å; F232-M243 HydrophobicContact CZ-SD 3.83Å; V239-M243 HydrophobicContact CG1-CG 4.35Å; V239-M243 WeakPolarHBondContact O-CB 3.5Å; V239-M243 VanDerWaalsContact O-CG 3.27Å; V239-M243 WeakPolarHBondContact O-CG 3.37Å; V239-M243 PolarHBondContact O-N 3.44Å; R240-M243 PolarHBondContact O-N 3.44Å; M243-V246 WeakPolarHBondContact O-CB 3.17Å; M243-V246 PolarHBondContact O-N 3.44Å; M243-A247 WeakPolarHBondContact O-CB 3.33Å; M243-A247 PolarHBondContact O-N 2.82Å
244E82.4Confident73.1Confident97 Ų9785.6 Ų85.645%0.45347%0.465SS..Hα-helixtrans-64.1-45.1173.3-74171.8-176.400112R240 K241 V246 A247 A248R240-E244 IonicContact CZ-OE1 3.35Å; R240-E244 VanDerWaalsContact NH1-CD 3.33Å; R240-E244 IonicContact NH1-OE1 3.08Å; R240-E244 PolarHBondContact NH1-OE1 3.49Å; R240-E244 IonicContact NH1-OE2 2.67Å; R240-E244 PolarHBondContact NH1-OE2 3.36Å; R240-E244 WeakPolarHBondContact O-CG 3.4Å; R240-E244 PolarHBondContact O-N 3.15Å; K241-E244 PolarHBondContact O-N 2.98Å; E244-V246 VanDerWaalsContact C-N 3.34Å; E244-V246 PolarHBondContact O-N 2.62Å; E244-A247 PolarHBondContact O-N 3.47Å; E244-A248 WeakPolarHBondContact O-CB 3.38Å; E244-A248 PolarHBondContact O-N 3.37Å
245A79.1Confident72.1Confident54 Ų5488.1 Ų88.145%0.44647%0.469SS..Hα-helixtrans-63.6-39.9177.100000112.1K241 A242 A248 Q249K241-A245 WeakPolarHBondContact O-CB 3.05Å; K241-A245 PolarHBondContact O-N 2.89Å; A242-A245 PolarHBondContact O-N 2.85Å; A245-A248 PolarHBondContact O-N 3.09Å; A245-Q249 WeakPolarHBondContact O-CG 3.48Å; A245-Q249 PolarHBondContact O-N 3.36Å; A245-Q249 VanDerWaalsContact O-N 3.12Å
246V71.7Confident71.3Confident12 Ų1288.6 Ų88.67%0.07347%0.472CS..Hα-helixtrans-58.9-48.2172149.80000110.9N209 P211 A242 M243 E244 A248 Q249N209-V246 HydrophobicContact CB-CB 4.19Å; N209-V246 HydrophobicContact CB-CG1 3.35Å; N209-V246 HydrophobicContact CB-CG2 4.32Å; N209-V246 WeakPolarHBondContact O-CG1 2.97Å; P211-V246 HydrophobicContact CB-CG2 3.94Å; A242-V246 VanDerWaalsContact O-CB 3.22Å; A242-V246 WeakPolarHBondContact O-CB 3.3Å; A242-V246 WeakPolarHBondContact O-CG2 3.48Å; A242-V246 PolarHBondContact O-N 3.18Å; M243-V246 WeakPolarHBondContact O-CB 3.17Å; M243-V246 PolarHBondContact O-N 3.44Å; E244-V246 VanDerWaalsContact C-N 3.34Å; E244-V246 PolarHBondContact O-N 2.62Å; V246-A248 VanDerWaalsContact C-N 3.31Å; V246-A248 PolarHBondContact O-N 2.99Å; V246-Q249 PolarHBondContact O-N 3.02Å
247A69.1Low70.4Confident61 Ų6183.4 Ų83.450%0.50445%0.451SS..Hα-helixtrans-64.1-36.4177.800000112M243 E244 Q249 G250M243-A247 WeakPolarHBondContact O-CB 3.33Å; M243-A247 PolarHBondContact O-N 2.82Å; E244-A247 PolarHBondContact O-N 3.47Å; A247-Q249 VanDerWaalsContact C-N 3.35Å; A247-Q249 PolarHBondContact O-N 3.32Å; A247-G250 PolarHBondContact O-N 2.89Å
248A71.8Confident69.3Low56 Ų5682.2 Ų82.246%0.46345%0.449SS..Hα-helixtrans-68.6-28177.300000113.4E244 A245 V246 G250 K251E244-A248 WeakPolarHBondContact O-CB 3.38Å; E244-A248 PolarHBondContact O-N 3.37Å; A245-A248 PolarHBondContact O-N 3.09Å; V246-A248 VanDerWaalsContact C-N 3.31Å; V246-A248 PolarHBondContact O-N 2.99Å; A248-G250 PolarHBondContact O-N 3.26Å; A248-G250 VanDerWaalsContact O-N 3.09Å; A248-K251 PolarHBondContact O-N 2.67Å
249Q61.3Low68.2Low90 Ų9085.8 Ų85.842%0.42147%0.468SS..THydrogen-bonded Turntrans-64.7-12.1176.5-74.4175.420.200114.2A245 V246 A247A245-Q249 WeakPolarHBondContact O-CG 3.48Å; A245-Q249 PolarHBondContact O-N 3.36Å; A245-Q249 VanDerWaalsContact O-N 3.12Å; V246-Q249 PolarHBondContact O-N 3.02Å; A247-Q249 VanDerWaalsContact C-N 3.35Å; A247-Q249 PolarHBondContact O-N 3.32Å
250G48.1Very low67Low42 Ų4290.1 Ų90.143%0.43349%0.49SS..THydrogen-bonded Turntrans-97.3-6.9171.900000115.5A247 A248A247-G250 PolarHBondContact O-N 2.89Å; A248-G250 PolarHBondContact O-N 3.26Å; A248-G250 VanDerWaalsContact O-N 3.09Å
251K43.6Very low65.4Low166 Ų16687.5 Ų87.572%0.72249%0.491SS*.SBendtrans-95.7135.1174.3-61.9-175.9179.5-177.70108.1A248A248-K251 PolarHBondContact O-N 2.67Å
252A40.9Very low63.6Low81 Ų8185.8 Ų85.867%0.66949%0.493SS*.  trans-56.7141.2171.700000109.1
253K37Very low62.1Low273 Ų27391.6 Ų91.6100%1.18752%0.522SS*.  trans-93.90162.3-94-165.5175.6-171.90107.6

Retrieved 253 of 253 residues in 137.2 ms (Link to these results)