A0A096N3W2_PAPAN Loading...

UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.

AlphaFold DB (G7PPA1), UniProt , Accession A0A096N3W2, Species PAPAN (Papio anubis, Olive baboon), Gene DPAGT1, Length 408 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	30.8	Very low	58.3	Low	231 Å²	231	113.3 Å²	113.3	100%	1.138	57%	0.573	S	S	*	*				0	102.1	0	-161.2	168.8	78.4	0	0	105.5	A3	M1-A3 PolarHBondContact O-N 3.37Å
2	W	30.6	Very low	61.4	Low	234 Å²	234	111.3 Å²	111.3	89%	0.886	56%	0.564	S	S	*	*			trans	-76	89.7	-170.8	-68.9	66.8	0	0	0	108.7	F4	W2-F4 PolarHBondContact O-N 2.86Å
3	A	29.5	Very low	64.1	Low	83 Å²	83	104.4 Å²	104.4	69%	0.686	53%	0.531	S	S	*	.			trans	-76.8	96.2	167.1	0	0	0	0	0	106.6	M1 S5	M1-A3 PolarHBondContact O-N 3.37Å; A3-S5 VanDerWaalsContact C-N 3.3Å; A3-S5 PolarHBondContact O-N 3.27Å
4	F	37.6	Very low	66.6	Low	180 Å²	180	96.9 Å²	96.9	79%	0.789	49%	0.493	S	S	*	.			trans	-57.9	104.3	160.3	-81.3	-85.1	0	0	0	106.1	W2 E6	W2-F4 PolarHBondContact O-N 2.86Å; F4-E6 PolarHBondContact O-N 3.4Å
5	S	44.2	Very low	68.7	Low	92 Å²	92	94.4 Å²	94.4	64%	0.643	48%	0.481	S	S	*	.	P	Polyproline II helix	trans	-50.2	137.4	165.6	47	0	0	0	0	107.8	A3 L7	A3-S5 VanDerWaalsContact C-N 3.3Å; A3-S5 PolarHBondContact O-N 3.27Å; S5-L7 PolarHBondContact O-N 2.98Å; S5-L7 VanDerWaalsContact O-N 3.11Å
6	E	53.3	Low	70.5	Confident	190 Å²	190	94.1 Å²	94.1	89%	0.888	48%	0.48	S	S	*	.	P	Polyproline II helix	trans	-47.8	125.6	-176.8	-68.2	-170.7	165	0	0	109.9	F4 P8	F4-E6 PolarHBondContact O-N 3.4Å; E6-P8 WeakPolarHBondContact O-CD 3.44Å
7	L	60.5	Low	72.2	Confident	80 Å²	80	90.4 Å²	90.4	42%	0.419	46%	0.462	S	S	.	.	P	Polyproline II helix	trans	-54.8	127.5	179	-139.1	86.6	0	0	0	107.5	S5 M9 L11	S5-L7 PolarHBondContact O-N 2.98Å; S5-L7 VanDerWaalsContact O-N 3.11Å; L7-M9 PolarHBondContact O-N 3.25Å; L7-L11 HydrophobicContact CD2-CB 3.71Å; L7-L11 HydrophobicContact CG-CB 4.13Å
8	P	79.3	Confident	73.6	Confident	33 Å²	33	85.3 Å²	85.3	21%	0.214	44%	0.436	C	S	.	.	P	Polyproline II helix	trans	-47	131.6	177.1	-29	31.5	0	0	0	110.5	E6 P10 L11 L12	E6-P8 WeakPolarHBondContact O-CD 3.44Å; P8-P10 VanDerWaalsContact O-N 3.07Å; P8-L11 HydrophobicContact CB-CD1 4.37Å; P8-L11 HydrophobicContact CB-CG 4.45Å; P8-L11 HydrophobicContact CG-CD1 4.05Å; P8-L11 WeakPolarHBondContact O-CA 3.48Å; P8-L11 WeakPolarHBondContact O-CB 3.38Å; P8-L11 PolarHBondContact O-N 3.33Å; P8-L12 PolarHBondContact O-N 3.37Å
9	M	88.1	Confident	75	Confident	100 Å²	100	85.1 Å²	85.1	49%	0.493	44%	0.436	S	S	.	.	H	α-helix	trans	-46.4	-41.7	-176.7	-178.2	-76	-162.9	0	0	113.5	L7 L11 L12 V13 F76 L79	L7-M9 PolarHBondContact O-N 3.25Å; M9-L11 VanDerWaalsContact C-N 3.34Å; M9-L11 PolarHBondContact O-N 2.75Å; M9-L12 PolarHBondContact O-N 3.25Å; M9-V13 HydrophobicContact CE-CG2 3.87Å; M9-V13 PolarHBondContact O-N 3.06Å; M9-V13 HydrophobicContact SD-CG2 3.7Å; M9-F76 HydrophobicContact CE-CD1 4.43Å; M9-L79 HydrophobicContact CE-CD1 3.45Å; M9-L79 VanDerWaalsContact CE-CD1 3.45Å; M9-L79 HydrophobicContact SD-CD1 3.92Å
10	P	92.8	Very high	76.2	Confident	21 Å²	21	86.5 Å²	86.5	14%	0.136	44%	0.444	C	S	.	.	H	α-helix	trans	-59.1	-39.5	174.2	-25.5	35.8	0	0	0	113.6	P8 V13 N14 F73 P77 Y226	P8-P10 VanDerWaalsContact O-N 3.07Å; P10-V13 PolarHBondContact O-N 3.42Å; P10-N14 VanDerWaalsContact O-CB 3.31Å; P10-N14 WeakPolarHBondContact O-CB 3.5Å; P10-N14 PolarHBondContact O-N 2.97Å; P10-F73 HydrophobicContact CB-CE2 4.4Å; P10-F73 HydrophobicContact CB-CZ 4.07Å; P10-F73 WeakPolarHBondContact O-CE2 3.32Å; P10-F73 WeakPolarHBondContact O-CZ 3.37Å; P10-P77 HydrophobicContact CB-CG 4.39Å; P10-Y226 HydrophobicContact CB-CE1 3.97Å
11	L	95.2	Very high	77.2	Confident	2 Å²	2	82.5 Å²	82.5	1%	0.01	42%	0.424	C	S	.	.	H	α-helix	trans	-67.9	-35.5	177.3	-70.3	177.4	0	0	0	112.3	L7 P8 M9 N14 L15 L213 L225 Y226 I229	L7-L11 HydrophobicContact CD2-CB 3.71Å; L7-L11 HydrophobicContact CG-CB 4.13Å; P8-L11 HydrophobicContact CB-CD1 4.37Å; P8-L11 HydrophobicContact CB-CG 4.45Å; P8-L11 HydrophobicContact CG-CD1 4.05Å; P8-L11 WeakPolarHBondContact O-CA 3.48Å; P8-L11 WeakPolarHBondContact O-CB 3.38Å; P8-L11 PolarHBondContact O-N 3.33Å; M9-L11 VanDerWaalsContact C-N 3.34Å; M9-L11 PolarHBondContact O-N 2.75Å; L11-N14 PolarHBondContact O-N 3.19Å; L11-L15 WeakPolarHBondContact O-CB 3.48Å; L11-L15 PolarHBondContact O-N 3.47Å; L11-L213 HydrophobicContact CD1-CD1 4.47Å; L11-L225 HydrophobicContact CD1-CD1 4.08Å; L11-L225 HydrophobicContact CD2-CB 3.68Å; L11-L225 HydrophobicContact CD2-CD1 4.37Å; L11-Y226 HydrophobicContact CD2-CD1 3.69Å; L11-Y226 HydrophobicContact CD2-CE1 3.64Å; L11-Y226 HydrophobicContact CG-CE1 4.14Å; L11-I229 HydrophobicContact CD2-CD1 4.32Å
12	L	95.6	Very high	80.5	Confident	89 Å²	89	74.2 Å²	74.2	47%	0.466	38%	0.381	S	S	.	.	H	α-helix	trans	-64.6	-47	173.9	178.9	62.4	0	0	0	111.2	P8 M9 N14 L15 I16	P8-L12 PolarHBondContact O-N 3.37Å; M9-L12 PolarHBondContact O-N 3.25Å; L12-N14 VanDerWaalsContact C-N 3.3Å; L12-N14 PolarHBondContact O-N 2.84Å; L12-L15 PolarHBondContact O-N 3.43Å; L12-I16 HydrophobicContact CD1-CD1 4.39Å; L12-I16 HydrophobicContact CG-CD1 4.18Å; L12-I16 WeakPolarHBondContact O-CG1 3.34Å; L12-I16 PolarHBondContact O-N 2.97Å
13	V	96.4	Very high	83.7	Confident	22 Å²	22	66.9 Å²	66.9	13%	0.133	36%	0.362	C	S	.	.	H	α-helix	trans	-59.3	-45.9	175	175.3	0	0	0	0	110.2	M9 P10 L15 I16 V17 F73 F76	M9-V13 HydrophobicContact CE-CG2 3.87Å; M9-V13 PolarHBondContact O-N 3.06Å; M9-V13 HydrophobicContact SD-CG2 3.7Å; P10-V13 PolarHBondContact O-N 3.42Å; V13-L15 VanDerWaalsContact C-N 3.3Å; V13-L15 PolarHBondContact O-N 2.9Å; V13-I16 PolarHBondContact O-N 2.86Å; V13-I16 VanDerWaalsContact O-N 3.12Å; V13-V17 HydrophobicContact CG1-CG1 4.37Å; V13-V17 WeakPolarHBondContact O-CG2 3.44Å; V13-V17 PolarHBondContact O-N 3.25Å; V13-F73 HydrophobicContact CB-CE2 4.46Å; V13-F73 HydrophobicContact CG1-CD2 4.33Å; V13-F73 HydrophobicContact CG1-CE2 4.49Å; V13-F76 HydrophobicContact CB-CD1 4.1Å; V13-F76 HydrophobicContact CB-CG 4.39Å; V13-F76 HydrophobicContact CG1-CB 4.45Å; V13-F76 HydrophobicContact CG1-CD1 3.62Å; V13-F76 HydrophobicContact CG1-CD2 4.04Å; V13-F76 HydrophobicContact CG1-CE1 3.75Å; V13-F76 HydrophobicContact CG1-CE2 4.13Å; V13-F76 HydrophobicContact CG1-CG 3.77Å; V13-F76 HydrophobicContact CG1-CZ 3.99Å; V13-F76 HydrophobicContact CG2-CD1 3.85Å; V13-F76 HydrophobicContact CG2-CE1 4.15Å
14	N	98.1	Very high	87	Confident	0 Å²	0	64.5 Å²	64.5	0%	0	34%	0.343	C	S	.	.	H	α-helix	trans	-56.8	-44	178.8	-166.1	26.6	0	0	0	111.9	P10 L11 L12 V17 S18 F73 L225 Y226 P230	P10-N14 VanDerWaalsContact O-CB 3.31Å; P10-N14 WeakPolarHBondContact O-CB 3.5Å; P10-N14 PolarHBondContact O-N 2.97Å; L11-N14 PolarHBondContact O-N 3.19Å; L12-N14 VanDerWaalsContact C-N 3.3Å; L12-N14 PolarHBondContact O-N 2.84Å; N14-V17 VanDerWaalsContact O-CG2 3.27Å; N14-V17 WeakPolarHBondContact O-CG2 3.29Å; N14-S18 WeakPolarHBondContact O-CB 3.38Å; N14-S18 PolarHBondContact O-N 2.83Å; N14-S18 PolarHBondContact O-OG 3.38Å; N14-F73 HydrophobicContact CB-CD2 4.07Å; N14-F73 HydrophobicContact CB-CE1 4.45Å; N14-F73 HydrophobicContact CB-CE2 3.61Å; N14-F73 HydrophobicContact CB-CZ 3.81Å; N14-L225 PolarHBondContact ND2-O 3.27Å; N14-Y226 WeakPolarHBondContact ND2-CA 3.49Å; N14-Y226 PolarHBondContact ND2-O 2.94Å; N14-Y226 VanDerWaalsContact ND2-O 3.1Å; N14-P230 VanDerWaalsContact OD1-CG 3.24Å; N14-P230 WeakPolarHBondContact OD1-CG 3.41Å
15	L	98.4	Very high	89.9	Confident	59 Å²	59	56 Å²	56	31%	0.309	31%	0.305	S	S	.	.	H	α-helix	trans	-61.5	-45.3	176.2	179	61.1	0	0	0	111.8	L11 L12 V13 S18 L19 I229 F233	L11-L15 WeakPolarHBondContact O-CB 3.48Å; L11-L15 PolarHBondContact O-N 3.47Å; L12-L15 PolarHBondContact O-N 3.43Å; V13-L15 VanDerWaalsContact C-N 3.3Å; V13-L15 PolarHBondContact O-N 2.9Å; L15-S18 PolarHBondContact O-N 3.18Å; L15-L19 HydrophobicContact CD1-CD1 4.43Å; L15-L19 HydrophobicContact CD1-CG 4.43Å; L15-L19 HydrophobicContact CG-CD1 4.28Å; L15-L19 WeakPolarHBondContact O-CG 3.27Å; L15-L19 PolarHBondContact O-N 3.01Å; L15-I229 HydrophobicContact CD1-CG2 4.14Å; L15-F233 HydrophobicContact CD1-CE2 3.55Å; L15-F233 HydrophobicContact CD1-CZ 3.92Å
16	I	98.3	Very high	92.5	Very high	90 Å²	90	53 Å²	53	46%	0.462	28%	0.283	S	S	.	.	H	α-helix	trans	-60.5	-51	178.8	-66.6	165.2	0	0	0	110.6	L12 V13 S18 L19 L20	L12-I16 HydrophobicContact CD1-CD1 4.39Å; L12-I16 HydrophobicContact CG-CD1 4.18Å; L12-I16 WeakPolarHBondContact O-CG1 3.34Å; L12-I16 PolarHBondContact O-N 2.97Å; V13-I16 PolarHBondContact O-N 2.86Å; V13-I16 VanDerWaalsContact O-N 3.12Å; I16-S18 VanDerWaalsContact C-N 3.26Å; I16-S18 PolarHBondContact O-N 3.21Å; I16-L19 PolarHBondContact O-N 2.69Å; I16-L20 WeakPolarHBondContact O-CG 3.38Å; I16-L20 PolarHBondContact O-N 2.9Å; I16-L20 VanDerWaalsContact O-N 3.1Å
17	V	98.4	Very high	94.7	Very high	30 Å²	30	48 Å²	48	18%	0.182	27%	0.266	C	S	.	.	H	α-helix	trans	-67.2	-28.8	179.8	-61.2	0	0	0	0	112.3	V13 N14 L20 G21 I69	V13-V17 HydrophobicContact CG1-CG1 4.37Å; V13-V17 WeakPolarHBondContact O-CG2 3.44Å; V13-V17 PolarHBondContact O-N 3.25Å; N14-V17 VanDerWaalsContact O-CG2 3.27Å; N14-V17 WeakPolarHBondContact O-CG2 3.29Å; V17-L20 PolarHBondContact O-N 2.86Å; V17-G21 PolarHBondContact O-N 3.43Å; V17-I69 HydrophobicContact CB-CG2 4.13Å; V17-I69 HydrophobicContact CG2-CG2 3.58Å
18	S	98.8	Very high	96.5	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-69.6	-39.9	174.3	-61.3	0	0	0	0	112.5	N14 L15 I16 G21 F22 P230 F233	N14-S18 WeakPolarHBondContact O-CB 3.38Å; N14-S18 PolarHBondContact O-N 2.83Å; N14-S18 PolarHBondContact O-OG 3.38Å; L15-S18 PolarHBondContact O-N 3.18Å; I16-S18 VanDerWaalsContact C-N 3.26Å; I16-S18 PolarHBondContact O-N 3.21Å; S18-G21 CarbonylContact O-C 3.54Å; S18-G21 WeakPolarHBondContact O-CA 3.46Å; S18-G21 PolarHBondContact O-N 3.2Å; S18-G21 VanDerWaalsContact O-N 3.12Å; S18-F22 PolarHBondContact O-N 3.47Å; S18-P230 VanDerWaalsContact OG-CA 3.28Å; S18-P230 WeakPolarHBondContact OG-CA 3.48Å; S18-P230 WeakPolarHBondContact OG-CD 3.39Å; S18-P230 VanDerWaalsContact OG-CG 3.31Å; S18-P230 WeakPolarHBondContact OG-CG 3.12Å; S18-F233 VanDerWaalsContact O-CB 3.31Å; S18-F233 WeakPolarHBondContact O-CB 3.45Å
19	L	98.8	Very high	97.5	Very high	81 Å²	81	45.7 Å²	45.7	42%	0.424	25%	0.252	S	S	.	.	H	α-helix	trans	-63.2	-41.9	173.4	-72.8	166.8	0	0	0	111.5	L15 I16 G21 F22 V23 F233	L15-L19 HydrophobicContact CD1-CD1 4.43Å; L15-L19 HydrophobicContact CD1-CG 4.43Å; L15-L19 HydrophobicContact CG-CD1 4.28Å; L15-L19 WeakPolarHBondContact O-CG 3.27Å; L15-L19 PolarHBondContact O-N 3.01Å; I16-L19 PolarHBondContact O-N 2.69Å; L19-G21 VanDerWaalsContact C-N 3.27Å; L19-G21 PolarHBondContact O-N 3.41Å; L19-F22 WeakPolarHBondContact O-CB 3.32Å; L19-F22 PolarHBondContact O-N 2.7Å; L19-V23 PolarHBondContact O-N 2.96Å; L19-F233 HydrophobicContact CD2-CD1 4Å; L19-F233 HydrophobicContact CD2-CE1 3.39Å; L19-F233 HydrophobicContact CD2-CZ 3.7Å; L19-F233 HydrophobicContact CG-CE1 4.3Å; L19-F233 HydrophobicContact CG-CZ 4.28Å
20	L	98.7	Very high	98	Very high	113 Å²	113	44 Å²	44	59%	0.592	25%	0.249	S	C	*	.	H	α-helix	trans	-61.8	-39.1	171.1	-65.7	175	0	0	0	111.3	I16 V17 F22 V23 A24	I16-L20 WeakPolarHBondContact O-CG 3.38Å; I16-L20 PolarHBondContact O-N 2.9Å; I16-L20 VanDerWaalsContact O-N 3.1Å; V17-L20 PolarHBondContact O-N 2.86Å; L20-F22 PolarHBondContact O-N 3.07Å; L20-V23 PolarHBondContact O-N 3.1Å; L20-A24 WeakPolarHBondContact O-CB 3.47Å; L20-A24 PolarHBondContact O-N 3.24Å
21	G	98.8	Very high	98.2	Very high	3 Å²	3	46.3 Å²	46.3	3%	0.031	27%	0.269	C	S	.	.	H	α-helix	trans	-57.7	-42.4	172.6	0	0	0	0	0	114.7	V17 S18 L19 A24 T25 I69	V17-G21 PolarHBondContact O-N 3.43Å; S18-G21 CarbonylContact O-C 3.54Å; S18-G21 WeakPolarHBondContact O-CA 3.46Å; S18-G21 PolarHBondContact O-N 3.2Å; S18-G21 VanDerWaalsContact O-N 3.12Å; L19-G21 VanDerWaalsContact C-N 3.27Å; L19-G21 PolarHBondContact O-N 3.41Å; G21-A24 PolarHBondContact O-N 3.36Å; G21-T25 WeakPolarHBondContact O-CB 3.16Å; G21-T25 PolarHBondContact O-N 3.14Å; G21-T25 PolarHBondContact O-OG1 3.02Å; G21-I69 VanDerWaalsContact CA-CD1 3.48Å
22	F	98.9	Very high	98.4	Very high	56 Å²	56	50.4 Å²	50.4	25%	0.246	29%	0.287	C	S	.	.	H	α-helix	trans	-58.9	-50.7	172.7	166.3	-102.3	0	0	0	110.8	S18 L19 L20 A24 T25 V26 F233 L236	S18-F22 PolarHBondContact O-N 3.47Å; L19-F22 WeakPolarHBondContact O-CB 3.32Å; L19-F22 PolarHBondContact O-N 2.7Å; L20-F22 PolarHBondContact O-N 3.07Å; F22-A24 VanDerWaalsContact C-N 3.34Å; F22-A24 PolarHBondContact O-N 2.85Å; F22-T25 PolarHBondContact O-N 3.04Å; F22-V26 HydrophobicContact CD2-CG2 4.15Å; F22-V26 HydrophobicContact CE1-CG2 4.32Å; F22-V26 HydrophobicContact CE2-CG2 3.71Å; F22-V26 HydrophobicContact CZ-CG2 3.8Å; F22-V26 WeakPolarHBondContact O-CG2 3.49Å; F22-V26 PolarHBondContact O-N 3.3Å; F22-F233 HydrophobicContact CB-CB 4.09Å; F22-F233 HydrophobicContact CB-CD1 4.14Å; F22-F233 WeakPolarHBondContact CD2-O 3.36Å; F22-L236 HydrophobicContact CD2-CB 4.02Å; F22-L236 HydrophobicContact CD2-CD2 4.23Å; F22-L236 HydrophobicContact CD2-CG 4.07Å; F22-L236 HydrophobicContact CE2-CB 4.18Å; F22-L236 HydrophobicContact CE2-CD2 4.09Å; F22-L236 HydrophobicContact CE2-CG 3.78Å
23	V	98.9	Very high	98.5	Very high	80 Å²	80	50.8 Å²	50.8	49%	0.485	28%	0.282	S	S	.	.	H	α-helix	trans	-60.3	-44.7	178.7	177.3	0	0	0	0	111.1	L19 L20 T25 V26 T27	L19-V23 PolarHBondContact O-N 2.96Å; L20-V23 PolarHBondContact O-N 3.1Å; V23-T25 PolarHBondContact O-N 3.34Å; V23-V26 PolarHBondContact O-N 2.81Å; V23-T27 WeakPolarHBondContact O-CB 3.39Å; V23-T27 PolarHBondContact O-N 2.91Å; V23-T27 PolarHBondContact O-OG1 2.88Å
24	A	98.8	Very high	98.6	Very high	34 Å²	34	52.2 Å²	52.2	28%	0.281	30%	0.301	S	S	.	.	H	α-helix	trans	-59.5	-46.7	176.2	0	0	0	0	0	111.3	L20 G21 F22 V26 T27 L28 V65	L20-A24 WeakPolarHBondContact O-CB 3.47Å; L20-A24 PolarHBondContact O-N 3.24Å; G21-A24 PolarHBondContact O-N 3.36Å; F22-A24 VanDerWaalsContact C-N 3.34Å; F22-A24 PolarHBondContact O-N 2.85Å; A24-V26 PolarHBondContact O-N 3.33Å; A24-T27 PolarHBondContact O-N 3.39Å; A24-L28 HydrophobicContact CB-CD1 4.32Å; A24-L28 VanDerWaalsContact O-CB 3.29Å; A24-L28 WeakPolarHBondContact O-CB 3.21Å; A24-L28 WeakPolarHBondContact O-CG 3.2Å; A24-L28 PolarHBondContact O-N 3.45Å; A24-V65 HydrophobicContact CB-CG1 4.18Å; A24-V65 HydrophobicContact CB-CG2 4.48Å
25	T	98.9	Very high	98.6	Very high	0 Å²	0	58.2 Å²	58.2	0%	0	33%	0.329	C	S	.	.	H	α-helix	trans	-62.7	-46.1	179.6	-55	0	0	0	0	111.6	G21 F22 V23 T27 I29	G21-T25 WeakPolarHBondContact O-CB 3.16Å; G21-T25 PolarHBondContact O-N 3.14Å; G21-T25 PolarHBondContact O-OG1 3.02Å; F22-T25 PolarHBondContact O-N 3.04Å; V23-T25 PolarHBondContact O-N 3.34Å; T25-T27 PolarHBondContact O-N 2.92Å; T25-I29 HydrophobicContact CG2-CD1 3.63Å; T25-I29 HydrophobicContact CG2-CG1 4.28Å; T25-I29 VanDerWaalsContact O-CG1 3.29Å; T25-I29 WeakPolarHBondContact O-CG1 3.39Å; T25-I29 PolarHBondContact O-N 2.89Å
26	V	98.8	Very high	98.6	Very high	29 Å²	29	56.2 Å²	56.2	18%	0.176	32%	0.318	C	S	.	.	H	α-helix	trans	-60.8	-35.4	177.1	172.2	0	0	0	0	111.6	F22 V23 A24 P30 Y240 H241	F22-V26 HydrophobicContact CD2-CG2 4.15Å; F22-V26 HydrophobicContact CE1-CG2 4.32Å; F22-V26 HydrophobicContact CE2-CG2 3.71Å; F22-V26 HydrophobicContact CZ-CG2 3.8Å; F22-V26 WeakPolarHBondContact O-CG2 3.49Å; F22-V26 PolarHBondContact O-N 3.3Å; V23-V26 PolarHBondContact O-N 2.81Å; A24-V26 PolarHBondContact O-N 3.33Å; V26-P30 WeakPolarHBondContact O-CD 3.37Å; V26-P30 WeakPolarHBondContact O-CG 3.32Å; V26-Y240 HydrophobicContact CG1-CD1 3.89Å; V26-Y240 HydrophobicContact CG1-CE1 3.96Å; V26-Y240 HydrophobicContact CG2-CD1 4.34Å; V26-Y240 HydrophobicContact CG2-CG 4.3Å; V26-H241 PolarHBondContact O-NE2 2.88Å
27	T	98.8	Very high	98.6	Very high	86 Å²	86	55 Å²	55	53%	0.528	31%	0.312	S	S	.	.	H	α-helix	trans	-80.8	-41.7	-177.6	-53.1	0	0	0	0	112.4	V23 A24 T25 P30	V23-T27 WeakPolarHBondContact O-CB 3.39Å; V23-T27 PolarHBondContact O-N 2.91Å; V23-T27 PolarHBondContact O-OG1 2.88Å; A24-T27 PolarHBondContact O-N 3.39Å; T25-T27 PolarHBondContact O-N 2.92Å; T27-P30 WeakPolarHBondContact O-CD 3.48Å; T27-P30 WeakPolarHBondContact O-CG 3.35Å
28	L	98.8	Very high	98.6	Very high	64 Å²	64	57.6 Å²	57.6	34%	0.335	34%	0.336	S	S	.	.	H	α-helix	trans	-76.6	-36.3	-173.3	-66.9	169.5	0	0	0	112.7	A24 A31 F32 I61 V65	A24-L28 HydrophobicContact CB-CD1 4.32Å; A24-L28 VanDerWaalsContact O-CB 3.29Å; A24-L28 WeakPolarHBondContact O-CB 3.21Å; A24-L28 WeakPolarHBondContact O-CG 3.2Å; A24-L28 PolarHBondContact O-N 3.45Å; L28-A31 WeakPolarHBondContact O-CB 3.5Å; L28-A31 PolarHBondContact O-N 3.49Å; L28-A31 VanDerWaalsContact O-N 3.09Å; L28-F32 HydrophobicContact CB-CD2 4.3Å; L28-F32 HydrophobicContact CB-CE2 4.48Å; L28-F32 HydrophobicContact CD2-CE2 4.03Å; L28-F32 WeakPolarHBondContact O-CD2 3.42Å; L28-F32 PolarHBondContact O-N 3.18Å; L28-I61 HydrophobicContact CB-CG2 3.84Å; L28-V65 HydrophobicContact CD1-CG2 3.81Å
29	I	98.8	Very high	98.5	Very high	1 Å²	1	60.5 Å²	60.5	1%	0.005	36%	0.36	C	S	.	.	H	α-helix	trans	-51.2	-54.7	178.6	-74.8	171.7	0	0	0	112.7	T25 A31 F32 R33 Q58 I61 L238 H241 V248	T25-I29 HydrophobicContact CG2-CD1 3.63Å; T25-I29 HydrophobicContact CG2-CG1 4.28Å; T25-I29 VanDerWaalsContact O-CG1 3.29Å; T25-I29 WeakPolarHBondContact O-CG1 3.39Å; T25-I29 PolarHBondContact O-N 2.89Å; I29-A31 VanDerWaalsContact C-N 3.35Å; I29-A31 PolarHBondContact O-N 2.88Å; I29-F32 PolarHBondContact O-N 3.38Å; I29-R33 PolarHBondContact O-N 2.97Å; I29-Q58 HydrophobicContact CG2-CG 4.42Å; I29-I61 HydrophobicContact CG1-CB 4.26Å; I29-I61 HydrophobicContact CG1-CD1 4.23Å; I29-I61 HydrophobicContact CG1-CG2 4.08Å; I29-L238 HydrophobicContact CD1-CB 4.3Å; I29-L238 HydrophobicContact CD1-CD1 3.78Å; I29-H241 HydrophobicContact CG2-CB 4.05Å; I29-V248 HydrophobicContact CG2-CG1 3.67Å; I29-V248 HydrophobicContact CG2-CG2 4.21Å
30	P	98.4	Very high	98.5	Very high	65 Å²	65	67.1 Å²	67.1	42%	0.422	38%	0.379	S	S	.	.	H	α-helix	trans	-69.6	-31.6	177.5	26.7	-34.1	0	0	0	112.7	V26 T27 F32 R33	V26-P30 WeakPolarHBondContact O-CD 3.37Å; V26-P30 WeakPolarHBondContact O-CG 3.32Å; T27-P30 WeakPolarHBondContact O-CD 3.48Å; T27-P30 WeakPolarHBondContact O-CG 3.35Å; P30-F32 VanDerWaalsContact C-N 3.3Å; P30-F32 PolarHBondContact O-N 3.25Å; P30-R33 WeakPolarHBondContact O-CB 3.33Å; P30-R33 PolarHBondContact O-N 3.49Å
31	A	98.6	Very high	98.4	Very high	69 Å²	69	63 Å²	63	57%	0.57	36%	0.358	S	S	*	.	H	α-helix	trans	-62.5	-37.2	178.4	0	0	0	0	0	112.2	L28 I29	L28-A31 WeakPolarHBondContact O-CB 3.5Å; L28-A31 PolarHBondContact O-N 3.49Å; L28-A31 VanDerWaalsContact O-N 3.09Å; I29-A31 VanDerWaalsContact C-N 3.35Å; I29-A31 PolarHBondContact O-N 2.88Å
32	F	98.5	Very high	98.4	Very high	87 Å²	87	64.5 Å²	64.5	38%	0.382	37%	0.368	S	S	.	.	H	α-helix	trans	-86.6	-2.9	178.2	-79	-81.5	0	0	0	114.5	L28 I29 P30 G34 H35 F36 I61	L28-F32 HydrophobicContact CB-CD2 4.3Å; L28-F32 HydrophobicContact CB-CE2 4.48Å; L28-F32 HydrophobicContact CD2-CE2 4.03Å; L28-F32 WeakPolarHBondContact O-CD2 3.42Å; L28-F32 PolarHBondContact O-N 3.18Å; I29-F32 PolarHBondContact O-N 3.38Å; P30-F32 VanDerWaalsContact C-N 3.3Å; P30-F32 PolarHBondContact O-N 3.25Å; F32-G34 PolarHBondContact O-N 2.85Å; F32-G34 VanDerWaalsContact O-N 3.09Å; F32-H35 AromaticContact CD1-CD2 3.71Å; F32-H35 WeakPolarHBondContact O-CB 3.41Å; F32-H35 PolarHBondContact O-N 3.21Å; F32-F36 HydrophobicContact CB-CD2 4.22Å; F32-F36 HydrophobicContact CB-CE2 4.03Å; F32-F36 WeakPolarHBondContact O-CD2 3.17Å; F32-F36 PolarHBondContact O-N 3.36Å; F32-I61 HydrophobicContact CB-CD1 3.76Å; F32-I61 HydrophobicContact CD2-CD1 4.33Å; F32-I61 HydrophobicContact CG-CD1 4.31Å
33	R	98.1	Very high	98.2	Very high	98 Å²	98	62.6 Å²	62.6	37%	0.37	36%	0.364	S	S	.	.	H	α-helix	trans	-47.5	-45.4	-178.4	-177.9	-177.6	-176.5	98.8	2.4	112.9	I29 P30 H35 F36 I37 P55 R247	I29-R33 PolarHBondContact O-N 2.97Å; P30-R33 WeakPolarHBondContact O-CB 3.33Å; P30-R33 PolarHBondContact O-N 3.49Å; R33-H35 VanDerWaalsContact C-N 3.32Å; R33-H35 PolarHBondContact O-N 3.31Å; R33-F36 PolarHBondContact O-N 2.93Å; R33-I37 HydrophobicContact CG-CG1 4.39Å; R33-I37 WeakPolarHBondContact O-CG1 3.32Å; R33-I37 PolarHBondContact O-N 2.85Å; R33-I37 VanDerWaalsContact O-N 3.14Å; R33-P55 HydrophobicContact CG-CG 4.34Å; R33-R247 PolarHBondContact NH1-O 3.01Å; R33-R247 VanDerWaalsContact NH1-O 3.16Å
34	G	97.8	Very high	98.2	Very high	51 Å²	51	63 Å²	63	53%	0.526	36%	0.36	S	S	.	.	H	α-helix	trans	-59.2	-39.8	-179.4	0	0	0	0	0	113.3	F32 A38	F32-G34 PolarHBondContact O-N 2.85Å; F32-G34 VanDerWaalsContact O-N 3.09Å; G34-A38 VanDerWaalsContact O-CB 3.27Å; G34-A38 WeakPolarHBondContact O-CB 3.43Å; G34-A38 PolarHBondContact O-N 3.06Å
35	H	98.3	Very high	98.1	Very high	126 Å²	126	61.8 Å²	61.8	58%	0.583	35%	0.35	S	S	*	.	H	α-helix	trans	-67.2	-43.2	179.9	-66.8	-82.6	0	0	0	112.2	F32 R33 A38 A39	F32-H35 AromaticContact CD1-CD2 3.71Å; F32-H35 WeakPolarHBondContact O-CB 3.41Å; F32-H35 PolarHBondContact O-N 3.21Å; R33-H35 VanDerWaalsContact C-N 3.32Å; R33-H35 PolarHBondContact O-N 3.31Å; H35-A38 PolarHBondContact O-N 2.82Å; H35-A39 VanDerWaalsContact O-CB 3.27Å; H35-A39 WeakPolarHBondContact O-CB 3.5Å; H35-A39 PolarHBondContact O-N 3.06Å
36	F	98.4	Very high	98	Very high	17 Å²	17	66.5 Å²	66.5	8%	0.075	37%	0.374	C	S	.	.	H	α-helix	trans	-66.3	-42.4	179.1	-77.9	-98.7	0	0	0	112	F32 R33 A39 R40 L41 P55 E56 V60 I61 F113	F32-F36 HydrophobicContact CB-CD2 4.22Å; F32-F36 HydrophobicContact CB-CE2 4.03Å; F32-F36 WeakPolarHBondContact O-CD2 3.17Å; F32-F36 PolarHBondContact O-N 3.36Å; R33-F36 PolarHBondContact O-N 2.93Å; F36-A39 PolarHBondContact O-N 2.86Å; F36-R40 PolarHBondContact O-N 3.4Å; F36-L41 HydrophobicContact CB-CB 4.42Å; F36-L41 HydrophobicContact CD1-CB 3.83Å; F36-L41 HydrophobicContact CD1-CD1 4.05Å; F36-L41 HydrophobicContact CE1-CD1 4.27Å; F36-L41 PolarHBondContact O-N 3.08Å; F36-P55 HydrophobicContact CB-CB 3.87Å; F36-E56 WeakPolarHBondContact CD1-O 3.49Å; F36-V60 HydrophobicContact CE1-CG1 3.99Å; F36-V60 HydrophobicContact CZ-CG1 3.51Å; F36-I61 HydrophobicContact CE2-CD1 3.86Å; F36-I61 HydrophobicContact CE2-CG1 4.24Å; F36-I61 HydrophobicContact CZ-CD1 4.28Å; F36-I61 HydrophobicContact CZ-CG1 4.24Å; F36-F113 HydrophobicContact CE1-CE2 4.42Å
37	I	98.1	Very high	97.9	Very high	66 Å²	66	65.4 Å²	65.4	34%	0.338	37%	0.367	S	S	.	.	H	α-helix	trans	-63.2	-44.5	175.1	-62.5	-64	0	0	0	110.6	R33 A39 R40 C42 P55	R33-I37 HydrophobicContact CG-CG1 4.39Å; R33-I37 WeakPolarHBondContact O-CG1 3.32Å; R33-I37 PolarHBondContact O-N 2.85Å; R33-I37 VanDerWaalsContact O-N 3.14Å; I37-A39 VanDerWaalsContact C-N 3.32Å; I37-A39 PolarHBondContact O-N 2.97Å; I37-R40 PolarHBondContact O-N 2.82Å; I37-R40 VanDerWaalsContact O-N 3.12Å; I37-C42 HydrophobicContact CD1-CB 3.87Å; I37-P55 HydrophobicContact CD1-CB 4.37Å
38	A	98.1	Very high	97.8	Very high	84 Å²	84	63.6 Å²	63.6	69%	0.694	35%	0.352	S	S	*	.	H	α-helix	trans	-63.1	-37.2	177.3	0	0	0	0	0	112.6	G34 H35 R40	G34-A38 VanDerWaalsContact O-CB 3.27Å; G34-A38 WeakPolarHBondContact O-CB 3.43Å; G34-A38 PolarHBondContact O-N 3.06Å; H35-A38 PolarHBondContact O-N 2.82Å; A38-R40 PolarHBondContact O-N 3Å
39	A	97.6	Very high	97.6	Very high	61 Å²	61	65.5 Å²	65.5	50%	0.504	37%	0.366	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.5	-0	176.4	0	0	0	0	0	114	H35 F36 I37 L41	H35-A39 VanDerWaalsContact O-CB 3.27Å; H35-A39 WeakPolarHBondContact O-CB 3.5Å; H35-A39 PolarHBondContact O-N 3.06Å; F36-A39 PolarHBondContact O-N 2.86Å; I37-A39 VanDerWaalsContact C-N 3.32Å; I37-A39 PolarHBondContact O-N 2.97Å; A39-L41 HydrophobicContact CB-CD1 4.32Å; A39-L41 HydrophobicContact CB-CG 4.24Å; A39-L41 PolarHBondContact O-N 2.88Å
40	R	97.7	Very high	97.5	Very high	219 Å²	219	67.9 Å²	67.9	83%	0.826	38%	0.383	S	S	*	.	T	Hydrogen-bonded Turn	trans	58.8	24	-174	-53.6	-178.2	177.2	-176.3	-0.9	114	F36 I37 A38 C42	F36-R40 PolarHBondContact O-N 3.4Å; I37-R40 PolarHBondContact O-N 2.82Å; I37-R40 VanDerWaalsContact O-N 3.12Å; A38-R40 PolarHBondContact O-N 3Å; R40-C42 PolarHBondContact O-N 3.26Å; R40-C42 VanDerWaalsContact O-N 3.08Å
41	L	97.8	Very high	97.4	Very high	26 Å²	26	74.8 Å²	74.8	14%	0.136	40%	0.401	C	S	.	.			trans	-84.6	72	169.7	-67	176	0	0	0	108.4	F36 A39 E56 F113 V117	F36-L41 HydrophobicContact CB-CB 4.42Å; F36-L41 HydrophobicContact CD1-CB 3.83Å; F36-L41 HydrophobicContact CD1-CD1 4.05Å; F36-L41 HydrophobicContact CE1-CD1 4.27Å; F36-L41 PolarHBondContact O-N 3.08Å; A39-L41 HydrophobicContact CB-CD1 4.32Å; A39-L41 HydrophobicContact CB-CG 4.24Å; A39-L41 PolarHBondContact O-N 2.88Å; L41-E56 PolarHBondContact O-N 3.33Å; L41-F113 HydrophobicContact CD1-CE2 3.88Å; L41-F113 HydrophobicContact CD1-CZ 3.9Å; L41-V117 HydrophobicContact CD1-CG2 4.24Å; L41-V117 HydrophobicContact CD2-CG2 3.91Å
42	C	97.4	Very high	97.3	Very high	35 Å²	35	76.8 Å²	76.8	24%	0.236	40%	0.399	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-152.8	151.6	-177.8	60.2	0	0	0	0	111.7	I37 R40 Q53 I54	I37-C42 HydrophobicContact CD1-CB 3.87Å; R40-C42 PolarHBondContact O-N 3.26Å; R40-C42 VanDerWaalsContact O-N 3.08Å; C42-Q53 HydrophobicContact CB-CB 4.05Å; C42-Q53 PolarHBondContact O-OE1 3.04Å; C42-I54 CarbonylContact C-O 3.58Å; C42-I54 WeakPolarHBondContact CA-O 3.5Å; C42-I54 VanDerWaalsContact CB-O 3.23Å; C42-I54 WeakPolarHBondContact CB-O 3.39Å
43	G	96.6	Very high	97.2	Very high	17 Å²	17	76.6 Å²	76.6	18%	0.175	40%	0.399	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.5	162.2	178.2	0	0	0	0	0	112.5	Q53 I54	G43-Q53 VanDerWaalsContact C-OE1 3.26Å; G43-I54 PolarHBondContact N-O 3.34Å; G43-I54 PolarHBondContact O-N 2.93Å
44	Q	97.1	Very high	97.2	Very high	87 Å²	87	72 Å²	72	41%	0.407	38%	0.382	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-84.6	145.8	169.6	-67.4	-179.7	0.8	0	0	110.1	L46	Q44-L46 PolarHBondContact O-N 2.88Å
45	D	97.6	Very high	97.2	Very high	10 Å²	10	69.6 Å²	69.6	5%	0.053	36%	0.357	C	S	.	.			trans	-73.7	97	168	-166.4	-32.5	0	0	0	109.8	N47 K48 I54 N191 F249	D45-N47 PolarHBondContact O-N 2.87Å; D45-N47 VanDerWaalsContact O-N 3.09Å; D45-N47 PolarHBondContact OD1-N 3.2Å; D45-K48 HydrophobicContact CB-CB 4.15Å; D45-K48 HydrophobicContact CB-CD 4.29Å; D45-K48 HydrophobicContact CB-CG 4.31Å; D45-K48 PolarHBondContact O-N 2.92Å; D45-K48 WeakPolarHBondContact OD2-CD 3.1Å; D45-K48 WeakPolarHBondContact OD2-CE 3.25Å; D45-K48 IonicContact OD2-NZ 2.7Å; D45-K48 PolarHBondContact OD2-NZ 3.47Å; D45-I54 HydrophobicContact CB-CD1 4Å; D45-N191 PolarHBondContact OD2-ND2 3.39Å; D45-N191 PolarHBondContact OD2-OD1 3.27Å; D45-F249 HydrophobicContact CB-CZ 3.91Å
46	L	96.1	Very high	97.2	Very high	99 Å²	99	66 Å²	66	52%	0.518	34%	0.34	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63.1	-15.9	-174.8	-61.9	178.4	0	0	0	113.6	Q44 I304	Q44-L46 PolarHBondContact O-N 2.88Å; L46-I304 HydrophobicContact CB-CD1 3.46Å; L46-I304 VanDerWaalsContact CB-CD1 3.46Å; L46-I304 HydrophobicContact CD1-CD1 3.61Å; L46-I304 HydrophobicContact CG-CD1 4.18Å
47	N	96.9	Very high	97.2	Very high	6 Å²	6	65.2 Å²	65.2	3%	0.032	34%	0.337	C	S	.	.	T	Hydrogen-bonded Turn	trans	-101.1	8.9	180	-66.6	-30.8	0	0	0	112.8	D45 G189 P305 L307 L314	D45-N47 PolarHBondContact O-N 2.87Å; D45-N47 VanDerWaalsContact O-N 3.09Å; D45-N47 PolarHBondContact OD1-N 3.2Å; N47-G189 PolarHBondContact ND2-O 3.27Å; N47-P305 PolarHBondContact OD1-O 3.04Å; N47-L307 WeakPolarHBondContact O-CD2 3.22Å; N47-L314 HydrophobicContact CB-CD2 3.96Å
48	K	96.5	Very high	97.2	Very high	48 Å²	48	62.1 Å²	62.1	21%	0.209	32%	0.321	C	S	.	.	S	Bend	trans	-125.7	160.5	176.6	-66.6	-173.7	-173.4	135.8	0	111.5	D45 S50 N191	D45-K48 HydrophobicContact CB-CB 4.15Å; D45-K48 HydrophobicContact CB-CD 4.29Å; D45-K48 HydrophobicContact CB-CG 4.31Å; D45-K48 PolarHBondContact O-N 2.92Å; D45-K48 WeakPolarHBondContact OD2-CD 3.1Å; D45-K48 WeakPolarHBondContact OD2-CE 3.25Å; D45-K48 IonicContact OD2-NZ 2.7Å; D45-K48 PolarHBondContact OD2-NZ 3.47Å; K48-S50 VanDerWaalsContact C-N 3.34Å; K48-N191 WeakPolarHBondContact CE-ND2 3.31Å; K48-N191 PolarHBondContact NZ-ND2 3.46Å
49	T	96.1	Very high	97.3	Very high	103 Å²	103	58.1 Å²	58.1	63%	0.632	29%	0.288	S	S	*	.	S	Bend	trans	-76.3	-23.9	176.1	51.5	0	0	0	0	112.9	L307 I309	T49-L307 HydrophobicContact CG2-CD2 4Å; T49-I309 HydrophobicContact CG2-CG1 4.43Å; T49-I309 HydrophobicContact CG2-CG2 4.19Å
50	S	96.3	Very high	97.3	Very high	52 Å²	52	56.6 Å²	56.6	36%	0.364	27%	0.272	S	S	.	.			trans	-68.3	130.7	178.9	-176.2	0	0	0	0	111.1	K48 Q52	K48-S50 VanDerWaalsContact C-N 3.34Å; S50-Q52 VanDerWaalsContact C-N 3.34Å; S50-Q52 WeakPolarHBondContact OG-CG 3.26Å; S50-Q52 PolarHBondContact OG-N 3.37Å
51	R	95.3	Very high	97.4	Very high	209 Å²	209	46.9 Å²	46.9	79%	0.789	24%	0.237	S	C	*	.			trans	-93	9.8	176.4	-64.1	-170.6	174.7	-166.7	-1.1	113.5
52	Q	96.3	Very high	97.4	Very high	112 Å²	112	45.7 Å²	45.7	52%	0.523	23%	0.23	S	C	.	.			trans	-61.5	141.5	178.6	73.8	-175.5	-7.3	0	0	110.8	S50 I54	S50-Q52 VanDerWaalsContact C-N 3.34Å; S50-Q52 WeakPolarHBondContact OG-CG 3.26Å; S50-Q52 PolarHBondContact OG-N 3.37Å; Q52-I54 HydrophobicContact CG-CG1 4.29Å
53	Q	97.5	Very high	97.5	Very high	82 Å²	82	44 Å²	44	38%	0.383	22%	0.219	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-80.4	127.6	173.5	-66.8	-69	-18.4	0	0	109.4	C42 G43	C42-Q53 HydrophobicContact CB-CB 4.05Å; C42-Q53 PolarHBondContact O-OE1 3.04Å; G43-Q53 VanDerWaalsContact C-OE1 3.26Å
54	I	98.4	Very high	97.6	Very high	3 Å²	3	45.3 Å²	45.3	2%	0.015	23%	0.228	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-107.3	131.6	178.5	-66.1	178.2	0	0	0	107.2	C42 G43 D45 Q52 E56 S246 V248 F249	C42-I54 CarbonylContact C-O 3.58Å; C42-I54 WeakPolarHBondContact CA-O 3.5Å; C42-I54 VanDerWaalsContact CB-O 3.23Å; C42-I54 WeakPolarHBondContact CB-O 3.39Å; G43-I54 PolarHBondContact N-O 3.34Å; G43-I54 PolarHBondContact O-N 2.93Å; D45-I54 HydrophobicContact CB-CD1 4Å; Q52-I54 HydrophobicContact CG-CG1 4.29Å; I54-E56 PolarHBondContact O-N 2.97Å; I54-S246 WeakPolarHBondContact CD1-O 3.45Å; I54-V248 VanDerWaalsContact CG2-CA 3.43Å; I54-F249 HydrophobicContact CB-CD2 4.02Å; I54-F249 HydrophobicContact CB-CE2 3.7Å; I54-F249 HydrophobicContact CB-CZ 4.18Å; I54-F249 HydrophobicContact CD1-CE1 4.44Å; I54-F249 HydrophobicContact CD1-CE2 4.21Å; I54-F249 HydrophobicContact CD1-CZ 3.83Å; I54-F249 HydrophobicContact CG1-CE2 4.48Å; I54-F249 HydrophobicContact CG2-CD1 4.37Å; I54-F249 HydrophobicContact CG2-CD2 3.81Å; I54-F249 HydrophobicContact CG2-CE1 4.41Å; I54-F249 HydrophobicContact CG2-CE2 3.86Å; I54-F249 HydrophobicContact CG2-CG 4.07Å; I54-F249 HydrophobicContact CG2-CZ 4.16Å
55	P	98.4	Very high	97.7	Very high	0 Å²	0	41.8 Å²	41.8	0%	0	21%	0.213	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-60.9	131.1	-179.2	28.9	-37.4	0	0	0	110.6	R33 F36 I37 R247 V248 F249	R33-P55 HydrophobicContact CG-CG 4.34Å; F36-P55 HydrophobicContact CB-CB 3.87Å; I37-P55 HydrophobicContact CD1-CB 4.37Å; P55-R247 WeakPolarHBondContact CD-O 3.46Å; P55-V248 HydrophobicContact CG-CB 4.11Å; P55-V248 HydrophobicContact CG-CG1 3.73Å; P55-F249 PolarHBondContact O-N 3.12Å
56	E	97.8	Very high	97.8	Very high	50 Å²	50	41.3 Å²	41.3	23%	0.234	21%	0.21	C	C	.	.			trans	-94.9	173.5	-179.8	-165.5	61.6	-103.6	0	0	109.9	F36 L41 I54 Q58 F249 G251	F36-E56 WeakPolarHBondContact CD1-O 3.49Å; L41-E56 PolarHBondContact O-N 3.33Å; I54-E56 PolarHBondContact O-N 2.97Å; E56-Q58 PolarHBondContact O-N 2.85Å; E56-Q58 PolarHBondContact O-NE2 3.27Å; E56-F249 CarbonylContact C-O 3.52Å; E56-F249 VanDerWaalsContact CD-CB 3.42Å; E56-F249 WeakPolarHBondContact OE1-CB 3.14Å; E56-F249 WeakPolarHBondContact OE2-CB 3.23Å; E56-F249 VanDerWaalsContact OE2-CD2 3.28Å; E56-F249 WeakPolarHBondContact OE2-CD2 3.28Å; E56-G251 VanDerWaalsContact OE1-CA 3.26Å; E56-G251 WeakPolarHBondContact OE1-CA 3.41Å; E56-G251 PolarHBondContact OE1-N 3.04Å
57	S	98.1	Very high	97.9	Very high	1 Å²	1	37.4 Å²	37.4	1%	0.007	19%	0.19	C	C	.	.			trans	59.1	24.8	170.8	-52	0	0	0	0	114.9	G59 V60 D116 F249 V250	S57-G59 PolarHBondContact O-N 2.86Å; S57-G59 VanDerWaalsContact O-N 3.12Å; S57-V60 VanDerWaalsContact O-CG1 3.22Å; S57-V60 WeakPolarHBondContact O-CG1 3.39Å; S57-V60 PolarHBondContact O-N 3.48Å; S57-D116 WeakPolarHBondContact CB-OD2 3.46Å; S57-D116 WeakPolarHBondContact OG-CB 3.36Å; S57-D116 PolarHBondContact OG-OD2 3.47Å; S57-F249 PolarHBondContact N-O 3.46Å; S57-V250 CarbonylContact C-O 3.55Å; S57-V250 WeakPolarHBondContact CA-O 3.41Å
58	Q	98.8	Very high	98	Very high	0 Å²	0	42 Å²	42	0%	0	21%	0.213	C	C	.	.	T	Hydrogen-bonded Turn	trans	-67.4	-12.3	178.4	-64.5	-50.8	-77	0	0	113.4	I29 E56 V60 I61 S62 L238 V248 F249	I29-Q58 HydrophobicContact CG2-CG 4.42Å; E56-Q58 PolarHBondContact O-N 2.85Å; E56-Q58 PolarHBondContact O-NE2 3.27Å; Q58-V60 PolarHBondContact O-N 3.22Å; Q58-V60 VanDerWaalsContact O-N 3.16Å; Q58-I61 PolarHBondContact O-N 3.18Å; Q58-I61 VanDerWaalsContact OE1-CD1 3.23Å; Q58-S62 PolarHBondContact O-N 2.74Å; Q58-L238 HydrophobicContact CB-CD1 3.75Å; Q58-V248 HydrophobicContact CB-CB 4.26Å; Q58-V248 HydrophobicContact CB-CG2 4.04Å; Q58-V248 HydrophobicContact CG-CB 3.46Å; Q58-V248 VanDerWaalsContact CG-CB 3.46Å; Q58-V248 HydrophobicContact CG-CG1 3.9Å; Q58-V248 HydrophobicContact CG-CG2 3.79Å; Q58-F249 WeakPolarHBondContact CB-O 3.44Å; Q58-F249 PolarHBondContact N-O 3.43Å
59	G	98.7	Very high	98.1	Very high	0 Å²	0	40.4 Å²	40.4	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-52.5	-28.2	166.4	0	0	0	0	0	113.8	S57 I61 S62 G63 V250	S57-G59 PolarHBondContact O-N 2.86Å; S57-G59 VanDerWaalsContact O-N 3.12Å; G59-I61 VanDerWaalsContact C-N 3.32Å; G59-I61 PolarHBondContact O-N 2.87Å; G59-S62 WeakPolarHBondContact CA-OG 3.45Å; G59-S62 PolarHBondContact O-OG 3.28Å; G59-G63 PolarHBondContact O-N 3.5Å; G59-V250 WeakPolarHBondContact CA-O 3.48Å; G59-V250 PolarHBondContact N-O 3.15Å
60	V	98.8	Very high	98.2	Very high	30 Å²	30	35.5 Å²	35.5	18%	0.182	18%	0.177	C	C	.	.	H	α-helix	trans	-65.4	-34.7	177.5	78.1	0	0	0	0	112.1	F36 S57 Q58 A64 F113 T253	F36-V60 HydrophobicContact CE1-CG1 3.99Å; F36-V60 HydrophobicContact CZ-CG1 3.51Å; S57-V60 VanDerWaalsContact O-CG1 3.22Å; S57-V60 WeakPolarHBondContact O-CG1 3.39Å; S57-V60 PolarHBondContact O-N 3.48Å; Q58-V60 PolarHBondContact O-N 3.22Å; Q58-V60 VanDerWaalsContact O-N 3.16Å; V60-A64 VanDerWaalsContact O-CB 3.24Å; V60-A64 WeakPolarHBondContact O-CB 3.46Å; V60-A64 PolarHBondContact O-N 3.39Å; V60-F113 HydrophobicContact CB-CD2 3.85Å; V60-F113 HydrophobicContact CB-CE2 4.32Å; V60-F113 HydrophobicContact CB-CG 4.46Å; V60-F113 HydrophobicContact CG1-CD2 4.17Å; V60-F113 HydrophobicContact CG1-CE2 4.13Å; V60-F113 HydrophobicContact CG2-CB 4.23Å; V60-F113 HydrophobicContact CG2-CD2 3.8Å; V60-F113 HydrophobicContact CG2-CE2 4.32Å; V60-F113 HydrophobicContact CG2-CG 3.96Å; V60-T253 HydrophobicContact CB-CG2 3.92Å; V60-T253 HydrophobicContact CG2-CG2 4.41Å
61	I	98.9	Very high	98.3	Very high	15 Å²	15	38.2 Å²	38.2	8%	0.077	18%	0.182	C	C	.	.	H	α-helix	trans	-72.3	-49	179.2	-60.5	177.3	0	0	0	109.6	L28 I29 F32 F36 Q58 G59 G63 A64 V65	L28-I61 HydrophobicContact CB-CG2 3.84Å; I29-I61 HydrophobicContact CG1-CB 4.26Å; I29-I61 HydrophobicContact CG1-CD1 4.23Å; I29-I61 HydrophobicContact CG1-CG2 4.08Å; F32-I61 HydrophobicContact CB-CD1 3.76Å; F32-I61 HydrophobicContact CD2-CD1 4.33Å; F32-I61 HydrophobicContact CG-CD1 4.31Å; F36-I61 HydrophobicContact CE2-CD1 3.86Å; F36-I61 HydrophobicContact CE2-CG1 4.24Å; F36-I61 HydrophobicContact CZ-CD1 4.28Å; F36-I61 HydrophobicContact CZ-CG1 4.24Å; Q58-I61 PolarHBondContact O-N 3.18Å; Q58-I61 VanDerWaalsContact OE1-CD1 3.23Å; G59-I61 VanDerWaalsContact C-N 3.32Å; G59-I61 PolarHBondContact O-N 2.87Å; I61-G63 VanDerWaalsContact C-N 3.28Å; I61-G63 PolarHBondContact O-N 3.23Å; I61-A64 PolarHBondContact O-N 2.78Å; I61-V65 WeakPolarHBondContact O-CG2 3.26Å; I61-V65 PolarHBondContact O-N 2.53Å
62	S	98.8	Very high	98.4	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-62.2	-37.7	176.3	54.8	0	0	0	0	112.1	Q58 G59 F66	Q58-S62 PolarHBondContact O-N 2.74Å; G59-S62 WeakPolarHBondContact CA-OG 3.45Å; G59-S62 PolarHBondContact O-OG 3.28Å; S62-F66 VanDerWaalsContact O-CB 3.27Å; S62-F66 WeakPolarHBondContact O-CB 3.5Å; S62-F66 PolarHBondContact O-N 3.21Å
63	G	98.8	Very high	98.4	Very high	0 Å²	0	26.8 Å²	26.8	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-66.4	-42.3	175.3	0	0	0	0	0	112.5	G59 I61 F66 L67	G59-G63 PolarHBondContact O-N 3.5Å; I61-G63 VanDerWaalsContact C-N 3.28Å; I61-G63 PolarHBondContact O-N 3.23Å; G63-F66 WeakPolarHBondContact O-CB 3.48Å; G63-F66 PolarHBondContact O-N 3.09Å; G63-L67 WeakPolarHBondContact O-CG 3.41Å; G63-L67 PolarHBondContact O-N 3.2Å
64	A	98.9	Very high	98.4	Very high	45 Å²	45	24.1 Å²	24.1	37%	0.372	13%	0.134	S	C	.	.	H	α-helix	trans	-63.8	-45	175.1	0	0	0	0	0	111.9	V60 I61 F66 L67 I68	V60-A64 VanDerWaalsContact O-CB 3.24Å; V60-A64 WeakPolarHBondContact O-CB 3.46Å; V60-A64 PolarHBondContact O-N 3.39Å; I61-A64 PolarHBondContact O-N 2.78Å; A64-F66 VanDerWaalsContact C-N 3.31Å; A64-F66 PolarHBondContact O-N 2.95Å; A64-L67 PolarHBondContact O-N 2.93Å; A64-I68 WeakPolarHBondContact O-CG1 3.35Å; A64-I68 PolarHBondContact O-N 2.92Å
65	V	98.9	Very high	98.1	Very high	12 Å²	12	26.5 Å²	26.5	7%	0.073	15%	0.15	C	C	.	.	H	α-helix	trans	-60.4	-43.3	175	172.5	0	0	0	0	110.6	A24 L28 I61 L67 I68 I69 T234	A24-V65 HydrophobicContact CB-CG1 4.18Å; A24-V65 HydrophobicContact CB-CG2 4.48Å; L28-V65 HydrophobicContact CD1-CG2 3.81Å; I61-V65 WeakPolarHBondContact O-CG2 3.26Å; I61-V65 PolarHBondContact O-N 2.53Å; V65-L67 PolarHBondContact O-N 2.86Å; V65-I68 PolarHBondContact O-N 2.83Å; V65-I69 HydrophobicContact CG1-CD1 3.83Å; V65-I69 HydrophobicContact CG1-CG1 4.4Å; V65-I69 WeakPolarHBondContact O-CD1 3.48Å; V65-I69 WeakPolarHBondContact O-CG1 3.49Å; V65-I69 PolarHBondContact O-N 2.74Å; V65-T234 HydrophobicContact CB-CG2 4.39Å; V65-T234 HydrophobicContact CG1-CG2 3.9Å
66	F	98.9	Very high	97.9	Very high	0 Å²	0	29.6 Å²	29.6	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-57.1	-46.5	174.4	170.9	-90.9	0	0	0	112.8	S62 G63 A64 I69 L70 I105 F227 P230 F231 T234 F257 T261	S62-F66 VanDerWaalsContact O-CB 3.27Å; S62-F66 WeakPolarHBondContact O-CB 3.5Å; S62-F66 PolarHBondContact O-N 3.21Å; G63-F66 WeakPolarHBondContact O-CB 3.48Å; G63-F66 PolarHBondContact O-N 3.09Å; A64-F66 VanDerWaalsContact C-N 3.31Å; A64-F66 PolarHBondContact O-N 2.95Å; F66-I69 PolarHBondContact O-N 2.98Å; F66-L70 HydrophobicContact CD1-CD1 4.19Å; F66-L70 HydrophobicContact CD2-CD1 4.45Å; F66-L70 HydrophobicContact CE1-CD1 3.47Å; F66-L70 VanDerWaalsContact CE1-CD1 3.47Å; F66-L70 HydrophobicContact CE2-CD1 3.79Å; F66-L70 HydrophobicContact CE2-CG 4.47Å; F66-L70 HydrophobicContact CZ-CD1 3.26Å; F66-L70 HydrophobicContact CZ-CG 4.34Å; F66-L70 PolarHBondContact O-N 3.48Å; F66-I105 HydrophobicContact CD1-CG2 4.35Å; F66-I105 HydrophobicContact CE1-CD1 4.21Å; F66-I105 HydrophobicContact CE1-CG2 3.78Å; F66-I105 HydrophobicContact CZ-CD1 4.29Å; F66-F227 WeakPolarHBondContact CE2-O 3.04Å; F66-F227 HydrophobicContact CZ-CD1 4.09Å; F66-P230 HydrophobicContact CD2-CB 3.73Å; F66-P230 HydrophobicContact CE2-CB 3.91Å; F66-F231 HydrophobicContact CD2-CB 4.25Å; F66-F231 HydrophobicContact CE2-CB 3.82Å; F66-T234 HydrophobicContact CB-CG2 4.19Å; F66-F257 HydrophobicContact CB-CE2 4.41Å; F66-F257 HydrophobicContact CB-CZ 3.83Å; F66-F257 AromaticContact CD1-CE2 3.58Å; F66-F257 HydrophobicContact CD1-CE2 3.58Å; F66-F257 AromaticContact CD1-CZ 3.83Å; F66-F257 HydrophobicContact CD1-CZ 3.83Å; F66-F257 HydrophobicContact CD2-CE2 4.3Å; F66-F257 AromaticContact CD2-CZ 3.89Å; F66-F257 HydrophobicContact CD2-CZ 3.89Å; F66-F257 AromaticContact CE1-CE2 3.78Å; F66-F257 HydrophobicContact CE1-CE2 3.78Å; F66-F257 HydrophobicContact CE1-CZ 4.32Å; F66-F257 HydrophobicContact CE2-CE2 4.46Å; F66-F257 HydrophobicContact CE2-CZ 4.37Å; F66-F257 AromaticContact CG-CE2 3.85Å; F66-F257 HydrophobicContact CG-CE2 3.85Å; F66-F257 AromaticContact CG-CZ 3.58Å; F66-F257 HydrophobicContact CG-CZ 3.58Å; F66-F257 HydrophobicContact CZ-CE2 4.19Å; F66-T261 HydrophobicContact CZ-CG2 4.13Å
67	L	98.8	Very high	97.6	Very high	17 Å²	17	28.5 Å²	28.5	9%	0.089	16%	0.16	C	C	.	.	H	α-helix	trans	-63.9	-43.5	177.5	-68.6	174.9	0	0	0	111.9	G63 A64 V65 I69 L70 F71 L102 C106 I109	G63-L67 WeakPolarHBondContact O-CG 3.41Å; G63-L67 PolarHBondContact O-N 3.2Å; A64-L67 PolarHBondContact O-N 2.93Å; V65-L67 PolarHBondContact O-N 2.86Å; L67-I69 VanDerWaalsContact C-N 3.34Å; L67-I69 PolarHBondContact O-N 3.41Å; L67-L70 PolarHBondContact O-N 2.8Å; L67-F71 HydrophobicContact CB-CE2 4.25Å; L67-F71 HydrophobicContact CB-CZ 4.4Å; L67-F71 WeakPolarHBondContact O-CB 3.37Å; L67-F71 WeakPolarHBondContact O-CD2 3.46Å; L67-F71 WeakPolarHBondContact O-CG 3.48Å; L67-F71 PolarHBondContact O-N 3.18Å; L67-L102 HydrophobicContact CD2-CD2 3.9Å; L67-C106 HydrophobicContact CD1-CB 3.97Å; L67-C106 HydrophobicContact CD2-CB 3.88Å; L67-I109 HydrophobicContact CD1-CD1 3.85Å; L67-I109 HydrophobicContact CD2-CD1 4.22Å; L67-I109 HydrophobicContact CG-CD1 3.88Å
68	I	98.8	Very high	97.2	Very high	104 Å²	104	28.8 Å²	28.8	53%	0.533	16%	0.161	S	C	.	.	H	α-helix	trans	-60.6	-45.5	177.5	-68.5	167.3	0	0	0	110.6	A64 V65 L70 F71 C72	A64-I68 WeakPolarHBondContact O-CG1 3.35Å; A64-I68 PolarHBondContact O-N 2.92Å; V65-I68 PolarHBondContact O-N 2.83Å; I68-L70 VanDerWaalsContact C-N 3.34Å; I68-L70 PolarHBondContact O-N 3.26Å; I68-F71 PolarHBondContact O-N 2.9Å; I68-C72 PolarHBondContact O-N 3.32Å; I68-C72 PolarHBondContact O-SG 3.49Å; I68-C72 VanDerWaalsContact O-SG 3.35Å
69	I	98.7	Very high	96.4	Very high	13 Å²	13	30.9 Å²	30.9	7%	0.067	17%	0.172	C	C	.	.	H	α-helix	trans	-55.7	-52.1	176.4	-69.7	161.3	0	0	0	110.1	V17 G21 V65 F66 L67 C72 F73 P230 T234	V17-I69 HydrophobicContact CB-CG2 4.13Å; V17-I69 HydrophobicContact CG2-CG2 3.58Å; G21-I69 VanDerWaalsContact CA-CD1 3.48Å; V65-I69 HydrophobicContact CG1-CD1 3.83Å; V65-I69 HydrophobicContact CG1-CG1 4.4Å; V65-I69 WeakPolarHBondContact O-CD1 3.48Å; V65-I69 WeakPolarHBondContact O-CG1 3.49Å; V65-I69 PolarHBondContact O-N 2.74Å; F66-I69 PolarHBondContact O-N 2.98Å; L67-I69 VanDerWaalsContact C-N 3.34Å; L67-I69 PolarHBondContact O-N 3.41Å; I69-C72 PolarHBondContact O-N 2.92Å; I69-F73 VanDerWaalsContact O-CB 3.27Å; I69-F73 WeakPolarHBondContact O-CB 3.4Å; I69-F73 PolarHBondContact O-N 2.88Å; I69-P230 HydrophobicContact CG2-CB 4.04Å; I69-P230 HydrophobicContact CG2-CG 4.05Å; I69-T234 HydrophobicContact CD1-CG2 3.81Å
70	L	98.6	Very high	95.3	Very high	1 Å²	1	34.8 Å²	34.8	1%	0.005	19%	0.193	C	C	.	.	H	α-helix	trans	-69	-35.7	-176.5	-74.4	-177.3	0	0	0	112.6	F66 L67 I68 C72 F73 I74 L102 Y226 F227 P230	F66-L70 HydrophobicContact CD1-CD1 4.19Å; F66-L70 HydrophobicContact CD2-CD1 4.45Å; F66-L70 HydrophobicContact CE1-CD1 3.47Å; F66-L70 VanDerWaalsContact CE1-CD1 3.47Å; F66-L70 HydrophobicContact CE2-CD1 3.79Å; F66-L70 HydrophobicContact CE2-CG 4.47Å; F66-L70 HydrophobicContact CZ-CD1 3.26Å; F66-L70 HydrophobicContact CZ-CG 4.34Å; F66-L70 PolarHBondContact O-N 3.48Å; L67-L70 PolarHBondContact O-N 2.8Å; I68-L70 VanDerWaalsContact C-N 3.34Å; I68-L70 PolarHBondContact O-N 3.26Å; L70-C72 VanDerWaalsContact C-N 3.34Å; L70-C72 PolarHBondContact O-N 2.97Å; L70-F73 HydrophobicContact CD2-CD1 4.2Å; L70-F73 WeakPolarHBondContact O-CB 3.43Å; L70-F73 PolarHBondContact O-N 3.5Å; L70-I74 WeakPolarHBondContact O-CG1 3.5Å; L70-I74 PolarHBondContact O-N 3.37Å; L70-L102 HydrophobicContact CB-CD1 4.09Å; L70-L102 HydrophobicContact CB-CD2 3.69Å; L70-L102 HydrophobicContact CB-CG 4.4Å; L70-L102 HydrophobicContact CD1-CD2 3.52Å; L70-L102 HydrophobicContact CD1-CG 4.35Å; L70-L102 HydrophobicContact CG-CD2 4.27Å; L70-Y226 WeakPolarHBondContact CD2-O 3.28Å; L70-F227 HydrophobicContact CD1-CD1 3.58Å; L70-F227 HydrophobicContact CD1-CE1 3.79Å; L70-F227 HydrophobicContact CD1-CG 4.43Å; L70-P230 HydrophobicContact CD2-CG 3.94Å; L70-P230 HydrophobicContact CG-CG 4.44Å
71	F	98.3	Very high	94.1	Very high	109 Å²	109	34.8 Å²	34.8	48%	0.478	19%	0.194	S	C	.	.	H	α-helix	trans	-60.8	-43.4	173	-68.1	-19.7	0	0	0	112.2	L67 I68 F73 I74 L102	L67-F71 HydrophobicContact CB-CE2 4.25Å; L67-F71 HydrophobicContact CB-CZ 4.4Å; L67-F71 WeakPolarHBondContact O-CB 3.37Å; L67-F71 WeakPolarHBondContact O-CD2 3.46Å; L67-F71 WeakPolarHBondContact O-CG 3.48Å; L67-F71 PolarHBondContact O-N 3.18Å; I68-F71 PolarHBondContact O-N 2.9Å; F71-F73 VanDerWaalsContact C-N 3.28Å; F71-F73 PolarHBondContact O-N 3.43Å; F71-I74 HydrophobicContact CD1-CD1 4.08Å; F71-L102 HydrophobicContact CD1-CD1 4.02Å; F71-L102 HydrophobicContact CE1-CD1 4.1Å; F71-L102 HydrophobicContact CE1-CD2 4.46Å
72	C	97.5	Very high	92.8	Very high	80 Å²	80	39.6 Å²	39.6	54%	0.541	22%	0.215	S	C	.	.	H	α-helix	trans	-68.3	-29.1	173.1	-66.2	0	0	0	0	112.3	I68 I69 L70 P75 F76	I68-C72 PolarHBondContact O-N 3.32Å; I68-C72 PolarHBondContact O-SG 3.49Å; I68-C72 VanDerWaalsContact O-SG 3.35Å; I69-C72 PolarHBondContact O-N 2.92Å; L70-C72 VanDerWaalsContact C-N 3.34Å; L70-C72 PolarHBondContact O-N 2.97Å; C72-P75 WeakPolarHBondContact O-CD 3.45Å; C72-F76 WeakPolarHBondContact O-CD2 3.09Å; C72-F76 VanDerWaalsContact O-CE2 3.27Å; C72-F76 WeakPolarHBondContact O-CE2 3.46Å
73	F	97.2	Very high	91.4	Very high	1 Å²	1	44.7 Å²	44.7	0%	0.004	25%	0.245	C	C	.	.	H	α-helix	trans	-77.6	-27.5	-179	-178.1	-110.5	0	0	0	114	P10 V13 N14 I69 L70 F71 P75 F76 P77 Y226	P10-F73 HydrophobicContact CB-CE2 4.4Å; P10-F73 HydrophobicContact CB-CZ 4.07Å; P10-F73 WeakPolarHBondContact O-CE2 3.32Å; P10-F73 WeakPolarHBondContact O-CZ 3.37Å; V13-F73 HydrophobicContact CB-CE2 4.46Å; V13-F73 HydrophobicContact CG1-CD2 4.33Å; V13-F73 HydrophobicContact CG1-CE2 4.49Å; N14-F73 HydrophobicContact CB-CD2 4.07Å; N14-F73 HydrophobicContact CB-CE1 4.45Å; N14-F73 HydrophobicContact CB-CE2 3.61Å; N14-F73 HydrophobicContact CB-CZ 3.81Å; I69-F73 VanDerWaalsContact O-CB 3.27Å; I69-F73 WeakPolarHBondContact O-CB 3.4Å; I69-F73 PolarHBondContact O-N 2.88Å; L70-F73 HydrophobicContact CD2-CD1 4.2Å; L70-F73 WeakPolarHBondContact O-CB 3.43Å; L70-F73 PolarHBondContact O-N 3.5Å; F71-F73 VanDerWaalsContact C-N 3.28Å; F71-F73 PolarHBondContact O-N 3.43Å; F73-P75 VanDerWaalsContact C-N 3.32Å; F73-P75 VanDerWaalsContact O-N 3.07Å; F73-F76 HydrophobicContact CD2-CB 3.98Å; F73-F76 HydrophobicContact CD2-CD2 4.24Å; F73-F76 HydrophobicContact CD2-CG 4.38Å; F73-F76 HydrophobicContact CE2-CB 3.78Å; F73-F76 WeakPolarHBondContact O-CB 3.38Å; F73-F76 WeakPolarHBondContact O-CD2 3.49Å; F73-F76 PolarHBondContact O-N 3.3Å; F73-P77 HydrophobicContact CD1-CG 4.42Å; F73-P77 HydrophobicContact CE1-CG 3.62Å; F73-P77 HydrophobicContact CZ-CG 3.7Å; F73-P77 VanDerWaalsContact O-CD 3.24Å; F73-P77 WeakPolarHBondContact O-CD 3.46Å; F73-Y226 AromaticContact CE1-CD1 3.49Å; F73-Y226 HydrophobicContact CE1-CD1 3.49Å; F73-Y226 VanDerWaalsContact CE1-CD1 3.49Å; F73-Y226 HydrophobicContact CE1-CD2 4.16Å; F73-Y226 AromaticContact CE1-CE1 3.96Å; F73-Y226 HydrophobicContact CE1-CE1 3.96Å; F73-Y226 AromaticContact CE1-CG 3.61Å; F73-Y226 HydrophobicContact CE1-CG 3.61Å; F73-Y226 AromaticContact CZ-CD1 3.56Å; F73-Y226 HydrophobicContact CZ-CD1 3.56Å; F73-Y226 AromaticContact CZ-CE1 3.67Å; F73-Y226 HydrophobicContact CZ-CE1 3.67Å; F73-Y226 HydrophobicContact CZ-CG 4.17Å
74	I	95.8	Very high	89.7	Confident	25 Å²	25	50.3 Å²	50.3	13%	0.128	27%	0.27	C	S	.	.	T	Hydrogen-bonded Turn	trans	-44.2	-44.9	-175.2	-76.9	159.4	0	0	0	114.5	L70 F71 F76 P77 F78 F95 L98 I99 L102	L70-I74 WeakPolarHBondContact O-CG1 3.5Å; L70-I74 PolarHBondContact O-N 3.37Å; F71-I74 HydrophobicContact CD1-CD1 4.08Å; I74-F76 VanDerWaalsContact C-N 3.28Å; I74-F76 PolarHBondContact O-N 3.14Å; I74-P77 WeakPolarHBondContact O-CD 3.22Å; I74-F78 WeakPolarHBondContact O-CD2 3.48Å; I74-F95 HydrophobicContact CG2-CD2 4.28Å; I74-F95 HydrophobicContact CG2-CE2 3.62Å; I74-L98 HydrophobicContact CB-CD2 4.22Å; I74-L98 HydrophobicContact CG1-CD2 3.74Å; I74-L98 HydrophobicContact CG1-CG 4.41Å; I74-L98 HydrophobicContact CG2-CD2 4.34Å; I74-I99 HydrophobicContact CD1-CD1 3.58Å; I74-I99 HydrophobicContact CG1-CD1 4.23Å; I74-L102 HydrophobicContact CD1-CD1 3.86Å; I74-L102 HydrophobicContact CG1-CD1 4.15Å
75	P	93.6	Very high	88	Confident	54 Å²	54	56.8 Å²	56.8	35%	0.351	29%	0.293	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.5	-22.6	-177.3	-20.7	34.5	0	0	0	114.1	C72 F73 F78 L79 F82	C72-P75 WeakPolarHBondContact O-CD 3.45Å; F73-P75 VanDerWaalsContact C-N 3.32Å; F73-P75 VanDerWaalsContact O-N 3.07Å; P75-F78 CarbonylContact O-C 3.31Å; P75-F78 PolarHBondContact O-N 3.26Å; P75-F78 VanDerWaalsContact O-N 3.12Å; P75-L79 PolarHBondContact O-N 2.91Å; P75-F82 HydrophobicContact CB-CD2 4.39Å; P75-F82 HydrophobicContact CB-CE2 4.45Å
76	F	92.8	Very high	86.4	Confident	65 Å²	65	63 Å²	63	29%	0.285	32%	0.321	S	S	.	.	G	3₁₀ helix	trans	-67.9	-45.6	-168.3	-72.4	-87.4	0	0	0	114.5	M9 V13 C72 F73 I74 F78 L79	M9-F76 HydrophobicContact CE-CD1 4.43Å; V13-F76 HydrophobicContact CB-CD1 4.1Å; V13-F76 HydrophobicContact CB-CG 4.39Å; V13-F76 HydrophobicContact CG1-CB 4.45Å; V13-F76 HydrophobicContact CG1-CD1 3.62Å; V13-F76 HydrophobicContact CG1-CD2 4.04Å; V13-F76 HydrophobicContact CG1-CE1 3.75Å; V13-F76 HydrophobicContact CG1-CE2 4.13Å; V13-F76 HydrophobicContact CG1-CG 3.77Å; V13-F76 HydrophobicContact CG1-CZ 3.99Å; V13-F76 HydrophobicContact CG2-CD1 3.85Å; V13-F76 HydrophobicContact CG2-CE1 4.15Å; C72-F76 WeakPolarHBondContact O-CD2 3.09Å; C72-F76 VanDerWaalsContact O-CE2 3.27Å; C72-F76 WeakPolarHBondContact O-CE2 3.46Å; F73-F76 HydrophobicContact CD2-CB 3.98Å; F73-F76 HydrophobicContact CD2-CD2 4.24Å; F73-F76 HydrophobicContact CD2-CG 4.38Å; F73-F76 HydrophobicContact CE2-CB 3.78Å; F73-F76 WeakPolarHBondContact O-CB 3.38Å; F73-F76 WeakPolarHBondContact O-CD2 3.49Å; F73-F76 PolarHBondContact O-N 3.3Å; I74-F76 VanDerWaalsContact C-N 3.28Å; I74-F76 PolarHBondContact O-N 3.14Å; F76-F78 PolarHBondContact O-N 3.22Å; F76-F78 VanDerWaalsContact O-N 3.11Å; F76-L79 HydrophobicContact CB-CD1 4.44Å; F76-L79 HydrophobicContact CD1-CD1 3.65Å; F76-L79 HydrophobicContact CD1-CG 4.39Å; F76-L79 HydrophobicContact CE1-CD1 4.38Å; F76-L79 HydrophobicContact CG-CD1 4.41Å; F76-L79 WeakPolarHBondContact O-CG 3.49Å; F76-L79 PolarHBondContact O-N 2.84Å
77	P	91.6	Very high	84.9	Confident	27 Å²	27	65.4 Å²	65.4	18%	0.175	34%	0.337	C	S	.	.	G	3₁₀ helix	trans	-55.2	-25.4	170.5	-27.9	36.1	0	0	0	114	P10 F73 I74 Y226	P10-P77 HydrophobicContact CB-CG 4.39Å; F73-P77 HydrophobicContact CD1-CG 4.42Å; F73-P77 HydrophobicContact CE1-CG 3.62Å; F73-P77 HydrophobicContact CZ-CG 3.7Å; F73-P77 VanDerWaalsContact O-CD 3.24Å; F73-P77 WeakPolarHBondContact O-CD 3.46Å; I74-P77 WeakPolarHBondContact O-CD 3.22Å; P77-Y226 HydrophobicContact CB-CE2 4.06Å; P77-Y226 HydrophobicContact CG-CD2 4.33Å; P77-Y226 HydrophobicContact CG-CE1 4.43Å; P77-Y226 HydrophobicContact CG-CE2 3.76Å
78	F	90.1	Very high	83.6	Confident	7 Å²	7	75.2 Å²	75.2	3%	0.031	38%	0.379	C	S	.	.	G	3₁₀ helix	trans	-108.6	14.8	-174	-50.4	-67	0	0	0	113.8	I74 P75 F76 N80 C81 F82 F90 P91 E94 F95 L98	I74-F78 WeakPolarHBondContact O-CD2 3.48Å; P75-F78 CarbonylContact O-C 3.31Å; P75-F78 PolarHBondContact O-N 3.26Å; P75-F78 VanDerWaalsContact O-N 3.12Å; F76-F78 PolarHBondContact O-N 3.22Å; F76-F78 VanDerWaalsContact O-N 3.11Å; F78-N80 VanDerWaalsContact C-N 3.28Å; F78-N80 PolarHBondContact O-N 2.94Å; F78-C81 WeakPolarHBondContact O-CA 3.46Å; F78-C81 WeakPolarHBondContact O-CB 3.37Å; F78-C81 PolarHBondContact O-N 2.87Å; F78-F82 HydrophobicContact CB-CD2 3.78Å; F78-F82 HydrophobicContact CB-CE2 3.71Å; F78-F82 WeakPolarHBondContact O-CD2 3.29Å; F78-F82 PolarHBondContact O-N 2.79Å; F78-F90 HydrophobicContact CB-CE2 4.02Å; F78-F90 HydrophobicContact CB-CZ 4.37Å; F78-F90 HydrophobicContact CD1-CE2 4.5Å; F78-F90 HydrophobicContact CD1-CZ 4.29Å; F78-F90 HydrophobicContact CD2-CZ 4.33Å; F78-F90 HydrophobicContact CG-CE2 4.19Å; F78-F90 HydrophobicContact CG-CZ 4.05Å; F78-P91 HydrophobicContact CD1-CG 3.49Å; F78-P91 VanDerWaalsContact CD1-CG 3.49Å; F78-P91 HydrophobicContact CE1-CG 3.73Å; F78-E94 HydrophobicContact CE1-CB 3.86Å; F78-E94 HydrophobicContact CZ-CB 4Å; F78-F95 HydrophobicContact CD2-CD2 4.19Å; F78-F95 HydrophobicContact CE1-CB 4.39Å; F78-F95 HydrophobicContact CE2-CB 4.2Å; F78-F95 AromaticContact CE2-CD2 3.72Å; F78-F95 HydrophobicContact CE2-CD2 3.72Å; F78-F95 HydrophobicContact CE2-CG 4.47Å; F78-F95 HydrophobicContact CZ-CB 3.86Å; F78-F95 HydrophobicContact CZ-CD2 4.26Å; F78-L98 HydrophobicContact CE2-CD2 4.15Å
79	L	82.8	Confident	82.9	Confident	43 Å²	43	74.1 Å²	74.1	23%	0.225	39%	0.385	C	S	.	.	H	α-helix	trans	-57	-35.7	-175.2	-80.7	169.7	0	0	0	114.4	M9 P75 F76 C81 F82 V83	M9-L79 HydrophobicContact CE-CD1 3.45Å; M9-L79 VanDerWaalsContact CE-CD1 3.45Å; M9-L79 HydrophobicContact SD-CD1 3.92Å; P75-L79 PolarHBondContact O-N 2.91Å; F76-L79 HydrophobicContact CB-CD1 4.44Å; F76-L79 HydrophobicContact CD1-CD1 3.65Å; F76-L79 HydrophobicContact CD1-CG 4.39Å; F76-L79 HydrophobicContact CE1-CD1 4.38Å; F76-L79 HydrophobicContact CG-CD1 4.41Å; F76-L79 WeakPolarHBondContact O-CG 3.49Å; F76-L79 PolarHBondContact O-N 2.84Å; L79-C81 PolarHBondContact O-N 3.41Å; L79-F82 PolarHBondContact O-N 3.08Å; L79-V83 HydrophobicContact CD2-CG2 3.73Å; L79-V83 WeakPolarHBondContact O-CB 3.4Å; L79-V83 PolarHBondContact O-N 2.97Å
80	N	74.9	Confident	82.3	Confident	82 Å²	82	76 Å²	76	44%	0.439	39%	0.393	S	S	.	.	H	α-helix	trans	-63.5	-28.3	177.7	-68.1	-29.3	0	0	0	111.7	F78 K84 Q86	F78-N80 VanDerWaalsContact C-N 3.28Å; F78-N80 PolarHBondContact O-N 2.94Å; N80-K84 WeakPolarHBondContact OD1-CD 3.48Å; N80-K84 WeakPolarHBondContact OD1-CE 3.39Å; N80-K84 PolarHBondContact OD1-NZ 3.18Å; N80-Q86 PolarHBondContact O-N 3.43Å
81	C	74.1	Confident	81.8	Confident	30 Å²	30	77.2 Å²	77.2	20%	0.203	40%	0.401	C	S	.	.	H	α-helix	trans	-83.7	-36.8	174.3	-56.4	0	0	0	0	112.6	F78 L79 C87 F90 P91	F78-C81 WeakPolarHBondContact O-CA 3.46Å; F78-C81 WeakPolarHBondContact O-CB 3.37Å; F78-C81 PolarHBondContact O-N 2.87Å; L79-C81 PolarHBondContact O-N 3.41Å; C81-C87 WeakPolarHBondContact CA-SG 3.36Å; C81-C87 HydrophobicContact CB-CB 3.64Å; C81-C87 WeakPolarHBondContact CB-SG 3.33Å; C81-C87 PolarHBondContact N-SG 3.05Å; C81-C87 WeakPolarHBondContact SG-CB 3.38Å; C81-C87 CovalentContact SG-SG 2.04Å; C81-C87 PolarHBondContact SG-SG 2.89Å; C81-F90 HydrophobicContact CB-CD2 4.09Å; C81-P91 VanDerWaalsContact SG-CD 3.52Å
82	F	71.8	Confident	81.3	Confident	117 Å²	117	77.7 Å²	77.7	51%	0.513	41%	0.405	S	S	.	.	H	α-helix	trans	-80.4	-36.1	-178.1	-78.1	-61.2	0	0	0	114.7	P75 F78 L79 F90	P75-F82 HydrophobicContact CB-CD2 4.39Å; P75-F82 HydrophobicContact CB-CE2 4.45Å; F78-F82 HydrophobicContact CB-CD2 3.78Å; F78-F82 HydrophobicContact CB-CE2 3.71Å; F78-F82 WeakPolarHBondContact O-CD2 3.29Å; F78-F82 PolarHBondContact O-N 2.79Å; L79-F82 PolarHBondContact O-N 3.08Å; F82-F90 HydrophobicContact CE1-CE2 4.42Å; F82-F90 AromaticContact CE2-CE2 3.88Å; F82-F90 HydrophobicContact CE2-CE2 3.88Å; F82-F90 HydrophobicContact CE2-CZ 4.39Å; F82-F90 AromaticContact CZ-CE2 3.76Å; F82-F90 HydrophobicContact CZ-CE2 3.76Å; F82-F90 HydrophobicContact CZ-CZ 4.24Å
83	V	69.6	Low	80.9	Confident	106 Å²	106	78.8 Å²	78.8	64%	0.642	40%	0.402	S	S	*	.	T	Hydrogen-bonded Turn	trans	-111.8	-37.3	-168.2	179.9	0	0	0	0	112.3	L79	L79-V83 HydrophobicContact CD2-CG2 3.73Å; L79-V83 WeakPolarHBondContact O-CB 3.4Å; L79-V83 PolarHBondContact O-N 2.97Å
84	K	62.2	Low	80.5	Confident	118 Å²	118	82.2 Å²	82.2	51%	0.513	42%	0.418	S	S	.	.	S	Bend	trans	-93.6	-3	-173.4	-61.7	-175.1	-174.1	160.6	0	114	N80 Q86	N80-K84 WeakPolarHBondContact OD1-CD 3.48Å; N80-K84 WeakPolarHBondContact OD1-CE 3.39Å; N80-K84 PolarHBondContact OD1-NZ 3.18Å; K84-Q86 HydrophobicContact CB-CB 4.14Å; K84-Q86 HydrophobicContact CB-CG 3.97Å; K84-Q86 WeakPolarHBondContact O-CG 3.3Å; K84-Q86 PolarHBondContact O-N 3.42Å
85	E	64	Low	80.4	Confident	182 Å²	182	83.9 Å²	83.9	85%	0.85	42%	0.424	S	S	*	.			trans	48.2	24.3	-172.6	-64.5	-175.1	168.2	0	0	113.5
86	Q	64.1	Low	80.4	Confident	141 Å²	141	84 Å²	84	66%	0.659	42%	0.424	S	S	*	.			trans	-89.9	-3.6	-170.7	-87.3	171.4	2.9	0	0	113.2	N80 K84	N80-Q86 PolarHBondContact O-N 3.43Å; K84-Q86 HydrophobicContact CB-CB 4.14Å; K84-Q86 HydrophobicContact CB-CG 3.97Å; K84-Q86 WeakPolarHBondContact O-CG 3.3Å; K84-Q86 PolarHBondContact O-N 3.42Å
87	C	67.8	Low	80.5	Confident	52 Å²	52	81.2 Å²	81.2	35%	0.351	41%	0.413	S	S	.	.			trans	-92.9	122.2	-178.5	-68.5	0	0	0	0	111.6	C81 A89	C81-C87 WeakPolarHBondContact CA-SG 3.36Å; C81-C87 HydrophobicContact CB-CB 3.64Å; C81-C87 WeakPolarHBondContact CB-SG 3.33Å; C81-C87 PolarHBondContact N-SG 3.05Å; C81-C87 WeakPolarHBondContact SG-CB 3.38Å; C81-C87 CovalentContact SG-SG 2.04Å; C81-C87 PolarHBondContact SG-SG 2.89Å; C87-A89 VanDerWaalsContact C-N 3.26Å; C87-A89 PolarHBondContact O-N 3.45Å
88	K	72.3	Confident	80.7	Confident	222 Å²	222	80.1 Å²	80.1	97%	0.965	41%	0.405	S	S	*	.	S	Bend	trans	-63	-33.3	170.5	-69.9	-176.3	177.9	179.7	0	112.4
89	A	82.9	Confident	81.1	Confident	81 Å²	81	82.9 Å²	82.9	67%	0.669	42%	0.42	S	S	*	.	S	Bend	trans	-149.9	148.2	174.4	0	0	0	0	0	109.3	C87	C87-A89 VanDerWaalsContact C-N 3.26Å; C87-A89 PolarHBondContact O-N 3.45Å
90	F	86	Confident	81.8	Confident	53 Å²	53	81.3 Å²	81.3	23%	0.232	41%	0.414	C	S	.	.			trans	-73.6	134.8	178.3	-176	-91.4	0	0	0	110.7	F78 C81 F82 H92 F95	F78-F90 HydrophobicContact CB-CE2 4.02Å; F78-F90 HydrophobicContact CB-CZ 4.37Å; F78-F90 HydrophobicContact CD1-CE2 4.5Å; F78-F90 HydrophobicContact CD1-CZ 4.29Å; F78-F90 HydrophobicContact CD2-CZ 4.33Å; F78-F90 HydrophobicContact CG-CE2 4.19Å; F78-F90 HydrophobicContact CG-CZ 4.05Å; C81-F90 HydrophobicContact CB-CD2 4.09Å; F82-F90 HydrophobicContact CE1-CE2 4.42Å; F82-F90 AromaticContact CE2-CE2 3.88Å; F82-F90 HydrophobicContact CE2-CE2 3.88Å; F82-F90 HydrophobicContact CE2-CZ 4.39Å; F82-F90 AromaticContact CZ-CE2 3.76Å; F82-F90 HydrophobicContact CZ-CE2 3.76Å; F82-F90 HydrophobicContact CZ-CZ 4.24Å; F90-H92 VanDerWaalsContact C-N 3.27Å; F90-H92 AromaticContact CD1-CD2 3.95Å; F90-H92 AromaticContact CD1-CE1 3.6Å; F90-H92 AromaticContact CD1-CG 3.83Å; F90-H92 AromaticContact CD1-ND1 3.61Å; F90-H92 AromaticContact CD1-NE2 3.82Å; F90-H92 PolarHBondContact O-CD2 3.43Å; F90-H92 PolarHBondContact O-N 3.33Å; F90-F95 HydrophobicContact CE1-CB 3.61Å; F90-F95 HydrophobicContact CE1-CD1 4.14Å; F90-F95 HydrophobicContact CE1-CD2 4.21Å; F90-F95 AromaticContact CE1-CG 3.73Å; F90-F95 HydrophobicContact CE1-CG 3.73Å; F90-F95 HydrophobicContact CZ-CB 4.09Å; F90-F95 AromaticContact CZ-CD2 3.99Å; F90-F95 HydrophobicContact CZ-CD2 3.99Å; F90-F95 HydrophobicContact CZ-CG 4Å
91	P	87.9	Confident	82.9	Confident	26 Å²	26	77.4 Å²	77.4	17%	0.169	39%	0.393	C	S	.	.			trans	-75.4	76.7	-179.1	32.2	-37.1	0	0	0	111.2	F78 C81 H93 F95	F78-P91 HydrophobicContact CD1-CG 3.49Å; F78-P91 VanDerWaalsContact CD1-CG 3.49Å; F78-P91 HydrophobicContact CE1-CG 3.73Å; C81-P91 VanDerWaalsContact SG-CD 3.52Å; P91-H93 PolarHBondContact O-N 2.99Å; P91-F95 PolarHBondContact O-N 2.94Å
92	H	89.1	Confident	84	Confident	120 Å²	120	76.1 Å²	76.1	56%	0.556	38%	0.384	S	S	*	.	H	α-helix	trans	-63.3	-27.6	-177.4	-73.9	-76.4	0	0	0	113.4	F90 F95 V96	F90-H92 VanDerWaalsContact C-N 3.27Å; F90-H92 AromaticContact CD1-CD2 3.95Å; F90-H92 AromaticContact CD1-CE1 3.6Å; F90-H92 AromaticContact CD1-CG 3.83Å; F90-H92 AromaticContact CD1-ND1 3.61Å; F90-H92 AromaticContact CD1-NE2 3.82Å; F90-H92 PolarHBondContact O-CD2 3.43Å; F90-H92 PolarHBondContact O-N 3.33Å; H92-F95 PolarHBondContact O-N 3.39Å; H92-V96 VanDerWaalsContact O-CB 3.27Å; H92-V96 WeakPolarHBondContact O-CB 3.2Å; H92-V96 WeakPolarHBondContact O-CG2 3.34Å; H92-V96 PolarHBondContact O-N 2.76Å
93	H	88.5	Confident	85.3	Confident	102 Å²	102	75.3 Å²	75.3	47%	0.472	38%	0.384	S	S	.	.	H	α-helix	trans	-62.2	-51.8	-179.4	60.5	-69.8	0	0	0	111.7	P91 V96 A97 N143	P91-H93 PolarHBondContact O-N 2.99Å; H93-V96 PolarHBondContact O-N 2.87Å; H93-A97 PolarHBondContact O-N 3.38Å; H93-A97 VanDerWaalsContact O-N 3.07Å; H93-N143 PolarHBondContact O-ND2 2.9Å
94	E	89	Confident	86.7	Confident	73 Å²	73	70.2 Å²	70.2	34%	0.341	35%	0.354	S	S	.	.	H	α-helix	trans	-64.3	-41	176.7	-83.4	161.5	-123.4	0	0	111.9	F78 A97 L98	F78-E94 HydrophobicContact CE1-CB 3.86Å; F78-E94 HydrophobicContact CZ-CB 4Å; E94-A97 PolarHBondContact O-N 3.26Å; E94-L98 WeakPolarHBondContact O-CB 3.41Å; E94-L98 PolarHBondContact O-N 2.97Å
95	F	92.7	Very high	88.4	Confident	60 Å²	60	64.6 Å²	64.6	26%	0.263	33%	0.329	S	S	.	.	H	α-helix	trans	-64.4	-44.7	179	-177.2	-104.4	0	0	0	112.1	I74 F78 F90 P91 H92 A97 L98 I99	I74-F95 HydrophobicContact CG2-CD2 4.28Å; I74-F95 HydrophobicContact CG2-CE2 3.62Å; F78-F95 HydrophobicContact CD2-CD2 4.19Å; F78-F95 HydrophobicContact CE1-CB 4.39Å; F78-F95 HydrophobicContact CE2-CB 4.2Å; F78-F95 AromaticContact CE2-CD2 3.72Å; F78-F95 HydrophobicContact CE2-CD2 3.72Å; F78-F95 HydrophobicContact CE2-CG 4.47Å; F78-F95 HydrophobicContact CZ-CB 3.86Å; F78-F95 HydrophobicContact CZ-CD2 4.26Å; F90-F95 HydrophobicContact CE1-CB 3.61Å; F90-F95 HydrophobicContact CE1-CD1 4.14Å; F90-F95 HydrophobicContact CE1-CD2 4.21Å; F90-F95 AromaticContact CE1-CG 3.73Å; F90-F95 HydrophobicContact CE1-CG 3.73Å; F90-F95 HydrophobicContact CZ-CB 4.09Å; F90-F95 AromaticContact CZ-CD2 3.99Å; F90-F95 HydrophobicContact CZ-CD2 3.99Å; F90-F95 HydrophobicContact CZ-CG 4Å; P91-F95 PolarHBondContact O-N 2.94Å; H92-F95 PolarHBondContact O-N 3.39Å; F95-A97 VanDerWaalsContact C-N 3.31Å; F95-A97 PolarHBondContact O-N 3.01Å; F95-L98 PolarHBondContact O-N 3.35Å; F95-I99 HydrophobicContact CD1-CG1 4.25Å; F95-I99 HydrophobicContact CD2-CG1 4.36Å; F95-I99 HydrophobicContact CE1-CG1 3.88Å; F95-I99 HydrophobicContact CE2-CD1 4.12Å; F95-I99 HydrophobicContact CE2-CG1 4Å; F95-I99 HydrophobicContact CG-CG1 4.48Å; F95-I99 HydrophobicContact CZ-CD1 4.02Å; F95-I99 HydrophobicContact CZ-CG1 3.75Å; F95-I99 WeakPolarHBondContact O-CG1 3.38Å; F95-I99 PolarHBondContact O-N 3.36Å
96	V	94.8	Very high	90.1	Very high	58 Å²	58	58.1 Å²	58.1	35%	0.352	30%	0.303	S	S	.	.	H	α-helix	trans	-61.4	-41.2	175.8	166.1	0	0	0	0	110.8	H92 H93 G100 V139	H92-V96 VanDerWaalsContact O-CB 3.27Å; H92-V96 WeakPolarHBondContact O-CB 3.2Å; H92-V96 WeakPolarHBondContact O-CG2 3.34Å; H92-V96 PolarHBondContact O-N 2.76Å; H93-V96 PolarHBondContact O-N 2.87Å; V96-G100 PolarHBondContact O-N 3.02Å; V96-V139 HydrophobicContact CG1-CG2 4.04Å
97	A	94.9	Very high	91.7	Very high	5 Å²	5	53.4 Å²	53.4	4%	0.041	29%	0.286	C	S	.	.	H	α-helix	trans	-61.5	-45.2	175.4	0	0	0	0	0	112.1	H93 E94 F95 A101 V139 F223 L268	H93-A97 PolarHBondContact O-N 3.38Å; H93-A97 VanDerWaalsContact O-N 3.07Å; E94-A97 PolarHBondContact O-N 3.26Å; F95-A97 VanDerWaalsContact C-N 3.31Å; F95-A97 PolarHBondContact O-N 3.01Å; A97-A101 WeakPolarHBondContact O-CB 3.48Å; A97-A101 PolarHBondContact O-N 3.34Å; A97-V139 HydrophobicContact CB-CG1 4.04Å; A97-F223 HydrophobicContact CB-CE2 3.87Å; A97-F223 HydrophobicContact CB-CZ 4.34Å; A97-L268 HydrophobicContact CB-CD1 4.43Å
98	L	96.1	Very high	93.1	Very high	4 Å²	4	51 Å²	51	2%	0.021	27%	0.269	C	S	.	.	H	α-helix	trans	-63	-47.5	179.4	-170.4	72.6	0	0	0	112.1	I74 F78 E94 F95 L102 F227	I74-L98 HydrophobicContact CB-CD2 4.22Å; I74-L98 HydrophobicContact CG1-CD2 3.74Å; I74-L98 HydrophobicContact CG1-CG 4.41Å; I74-L98 HydrophobicContact CG2-CD2 4.34Å; F78-L98 HydrophobicContact CE2-CD2 4.15Å; E94-L98 WeakPolarHBondContact O-CB 3.41Å; E94-L98 PolarHBondContact O-N 2.97Å; F95-L98 PolarHBondContact O-N 3.35Å; L98-L102 WeakPolarHBondContact O-CB 3.39Å; L98-L102 PolarHBondContact O-N 3.27Å; L98-F227 HydrophobicContact CD1-CE2 3.66Å; L98-F227 HydrophobicContact CD1-CZ 3.62Å; L98-F227 HydrophobicContact CG-CZ 4.49Å
99	I	97.5	Very high	94.4	Very high	66 Å²	66	40.8 Å²	40.8	34%	0.338	23%	0.225	S	C	.	.	H	α-helix	trans	-69.8	-43.4	-179.6	-62.1	-60.7	0	0	0	111.5	I74 F95 L102 L103	I74-I99 HydrophobicContact CD1-CD1 3.58Å; I74-I99 HydrophobicContact CG1-CD1 4.23Å; F95-I99 HydrophobicContact CD1-CG1 4.25Å; F95-I99 HydrophobicContact CD2-CG1 4.36Å; F95-I99 HydrophobicContact CE1-CG1 3.88Å; F95-I99 HydrophobicContact CE2-CD1 4.12Å; F95-I99 HydrophobicContact CE2-CG1 4Å; F95-I99 HydrophobicContact CG-CG1 4.48Å; F95-I99 HydrophobicContact CZ-CD1 4.02Å; F95-I99 HydrophobicContact CZ-CG1 3.75Å; F95-I99 WeakPolarHBondContact O-CG1 3.38Å; F95-I99 PolarHBondContact O-N 3.36Å; I99-L102 PolarHBondContact O-N 3.16Å; I99-L103 WeakPolarHBondContact O-CB 3.39Å; I99-L103 PolarHBondContact O-N 2.98Å
100	G	97.6	Very high	95.1	Very high	9 Å²	9	43.2 Å²	43.2	9%	0.093	22%	0.221	C	C	.	.	H	α-helix	trans	-66.1	-38.3	179.2	0	0	0	0	0	112.7	V96 L103 A104	V96-G100 PolarHBondContact O-N 3.02Å; G100-L103 PolarHBondContact O-N 3.28Å; G100-A104 PolarHBondContact O-N 3.42Å
101	A	98.1	Very high	95.6	Very high	0 Å²	0	41.8 Å²	41.8	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-59.5	-48.9	170.3	0	0	0	0	0	112.1	A97 L103 A104 I105 F223 F227 V264 L268	A97-A101 WeakPolarHBondContact O-CB 3.48Å; A97-A101 PolarHBondContact O-N 3.34Å; A101-L103 VanDerWaalsContact C-N 3.32Å; A101-L103 PolarHBondContact O-N 3.22Å; A101-A104 PolarHBondContact O-N 3.09Å; A101-I105 WeakPolarHBondContact O-CG1 3.49Å; A101-I105 PolarHBondContact O-N 2.82Å; A101-F223 HydrophobicContact CB-CZ 4.04Å; A101-F227 HydrophobicContact CB-CE1 3.8Å; A101-F227 HydrophobicContact CB-CE2 4.16Å; A101-F227 HydrophobicContact CB-CZ 3.4Å; A101-F227 VanDerWaalsContact CB-CZ 3.4Å; A101-V264 HydrophobicContact CB-CG1 3.41Å; A101-V264 VanDerWaalsContact CB-CG1 3.41Å; A101-L268 HydrophobicContact CB-CD1 4.06Å
102	L	98.2	Very high	96	Very high	4 Å²	4	40.6 Å²	40.6	2%	0.021	21%	0.207	C	C	.	.	H	α-helix	trans	-61.4	-39.3	176.3	-86.1	172.4	0	0	0	112.8	L67 L70 F71 I74 L98 I99 I105 C106 F227	L67-L102 HydrophobicContact CD2-CD2 3.9Å; L70-L102 HydrophobicContact CB-CD1 4.09Å; L70-L102 HydrophobicContact CB-CD2 3.69Å; L70-L102 HydrophobicContact CB-CG 4.4Å; L70-L102 HydrophobicContact CD1-CD2 3.52Å; L70-L102 HydrophobicContact CD1-CG 4.35Å; L70-L102 HydrophobicContact CG-CD2 4.27Å; F71-L102 HydrophobicContact CD1-CD1 4.02Å; F71-L102 HydrophobicContact CE1-CD1 4.1Å; F71-L102 HydrophobicContact CE1-CD2 4.46Å; I74-L102 HydrophobicContact CD1-CD1 3.86Å; I74-L102 HydrophobicContact CG1-CD1 4.15Å; L98-L102 WeakPolarHBondContact O-CB 3.39Å; L98-L102 PolarHBondContact O-N 3.27Å; I99-L102 PolarHBondContact O-N 3.16Å; L102-I105 PolarHBondContact O-N 2.82Å; L102-C106 WeakPolarHBondContact O-CB 3.44Å; L102-C106 PolarHBondContact O-N 3.44Å; L102-F227 HydrophobicContact CD2-CE1 4.27Å; L102-F227 HydrophobicContact CG-CE1 4.04Å; L102-F227 HydrophobicContact CG-CZ 4.49Å
103	L	98.4	Very high	96.5	Very high	99 Å²	99	37.9 Å²	37.9	52%	0.518	19%	0.194	S	C	.	.	H	α-helix	trans	-62.4	-44.8	176.3	179.4	59.8	0	0	0	111.2	I99 G100 A101 C107 P135	I99-L103 WeakPolarHBondContact O-CB 3.39Å; I99-L103 PolarHBondContact O-N 2.98Å; G100-L103 PolarHBondContact O-N 3.28Å; A101-L103 VanDerWaalsContact C-N 3.32Å; A101-L103 PolarHBondContact O-N 3.22Å; L103-C107 WeakPolarHBondContact O-CB 3.42Å; L103-C107 PolarHBondContact O-N 3.05Å; L103-P135 HydrophobicContact CB-CB 4.38Å; L103-P135 HydrophobicContact CD2-CB 4Å; L103-P135 HydrophobicContact CD2-CG 3.85Å; L103-P135 HydrophobicContact CG-CB 4.2Å; L103-P135 HydrophobicContact CG-CG 3.9Å
104	A	98.4	Very high	96.9	Very high	0 Å²	0	34 Å²	34	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-61.9	-45.8	176.2	0	0	0	0	0	111.9	G100 A101 M108 A132 P135 M260 V264	G100-A104 PolarHBondContact O-N 3.42Å; A101-A104 PolarHBondContact O-N 3.09Å; A104-M108 WeakPolarHBondContact O-CB 3.28Å; A104-M108 PolarHBondContact O-N 2.83Å; A104-A132 WeakPolarHBondContact CA-O 3.11Å; A104-A132 WeakPolarHBondContact CB-O 3.49Å; A104-P135 HydrophobicContact CB-CB 4.4Å; A104-M260 HydrophobicContact CB-CG 4.44Å; A104-M260 HydrophobicContact CB-SD 4.11Å; A104-V264 HydrophobicContact CB-CG2 4.28Å
105	I	98.8	Very high	97.2	Very high	0 Å²	0	30.6 Å²	30.6	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-66.7	-45	179.4	-64.7	164.3	0	0	0	111.5	F66 A101 L102 M108 I109 F227 F257 M260 T261 V264	F66-I105 HydrophobicContact CD1-CG2 4.35Å; F66-I105 HydrophobicContact CE1-CD1 4.21Å; F66-I105 HydrophobicContact CE1-CG2 3.78Å; F66-I105 HydrophobicContact CZ-CD1 4.29Å; A101-I105 WeakPolarHBondContact O-CG1 3.49Å; A101-I105 PolarHBondContact O-N 2.82Å; L102-I105 PolarHBondContact O-N 2.82Å; I105-M108 WeakPolarHBondContact O-CB 3.45Å; I105-M108 PolarHBondContact O-N 3.39Å; I105-M108 VanDerWaalsContact O-N 3.16Å; I105-I109 HydrophobicContact CG2-CD1 3.87Å; I105-I109 HydrophobicContact CG2-CG1 4.41Å; I105-I109 WeakPolarHBondContact O-CG1 2.94Å; I105-I109 PolarHBondContact O-N 2.9Å; I105-F227 HydrophobicContact CD1-CD1 3.68Å; I105-F227 HydrophobicContact CD1-CE1 3.89Å; I105-F257 HydrophobicContact CG2-CD2 3.73Å; I105-F257 HydrophobicContact CG2-CE2 3.84Å; I105-M260 HydrophobicContact CG1-CG 4.13Å; I105-T261 HydrophobicContact CD1-CG2 4.06Å; I105-V264 HydrophobicContact CD1-CB 4.44Å; I105-V264 HydrophobicContact CD1-CG1 4.3Å; I105-V264 HydrophobicContact CD1-CG2 4.35Å; I105-V264 HydrophobicContact CG1-CG2 4.05Å
106	C	98.6	Very high	97.4	Very high	46 Å²	46	28.7 Å²	28.7	31%	0.311	16%	0.157	S	C	.	.	H	α-helix	trans	-60.7	-47.2	177.5	-179.2	0	0	0	0	111.4	L67 L102 M108 I109 F110	L67-C106 HydrophobicContact CD1-CB 3.97Å; L67-C106 HydrophobicContact CD2-CB 3.88Å; L102-C106 WeakPolarHBondContact O-CB 3.44Å; L102-C106 PolarHBondContact O-N 3.44Å; C106-M108 PolarHBondContact O-N 2.97Å; C106-I109 PolarHBondContact O-N 3.34Å; C106-F110 WeakPolarHBondContact O-CB 3.48Å; C106-F110 PolarHBondContact O-N 2.88Å
107	C	98.2	Very high	97.5	Very high	42 Å²	42	29.3 Å²	29.3	28%	0.284	16%	0.16	S	C	.	.	H	α-helix	trans	-58	-40.9	174.8	-171	0	0	0	0	110.9	L103 F110 L111 A132	L103-C107 WeakPolarHBondContact O-CB 3.42Å; L103-C107 PolarHBondContact O-N 3.05Å; C107-F110 PolarHBondContact O-N 3.05Å; C107-L111 WeakPolarHBondContact O-CB 3.34Å; C107-L111 VanDerWaalsContact O-CG 3.23Å; C107-L111 WeakPolarHBondContact O-CG 3.47Å; C107-L111 PolarHBondContact O-N 3.4Å; C107-A132 HydrophobicContact CB-CB 4.2Å
108	M	97.8	Very high	97.5	Very high	0 Å²	0	34.6 Å²	34.6	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-69	-40.9	178.1	-174.8	60.5	76.8	0	0	113.9	A104 I105 C106 F110 L111 G112 P129 A132 T181 Y256 M260	A104-M108 WeakPolarHBondContact O-CB 3.28Å; A104-M108 PolarHBondContact O-N 2.83Å; I105-M108 WeakPolarHBondContact O-CB 3.45Å; I105-M108 PolarHBondContact O-N 3.39Å; I105-M108 VanDerWaalsContact O-N 3.16Å; C106-M108 PolarHBondContact O-N 2.97Å; M108-F110 VanDerWaalsContact C-N 3.29Å; M108-F110 PolarHBondContact O-N 3.5Å; M108-L111 PolarHBondContact O-N 2.83Å; M108-G112 PolarHBondContact O-N 2.8Å; M108-P129 VanDerWaalsContact CE-CA 3.44Å; M108-P129 HydrophobicContact CE-CB 3.59Å; M108-P129 HydrophobicContact CE-CG 3.93Å; M108-P129 HydrophobicContact SD-CG 4.49Å; M108-A132 HydrophobicContact CE-CB 4.03Å; M108-T181 HydrophobicContact CE-CG2 3.84Å; M108-T181 HydrophobicContact SD-CG2 4.24Å; M108-Y256 HydrophobicContact CG-CG 4.49Å; M108-Y256 WeakPolarHBondContact CG-O 3.29Å; M108-Y256 VanDerWaalsContact SD-CB 3.54Å; M108-Y256 HydrophobicContact SD-CD2 3.44Å; M108-Y256 WeakPolarHBondContact SD-CD2 3.33Å; M108-Y256 HydrophobicContact SD-CE2 4.45Å; M108-Y256 HydrophobicContact SD-CG 3.72Å; M108-M260 HydrophobicContact CB-CB 3.75Å; M108-M260 HydrophobicContact CB-CE 4.45Å; M108-M260 HydrophobicContact CB-CG 3.86Å; M108-M260 HydrophobicContact CE-CB 4.16Å; M108-M260 HydrophobicContact CE-CE 3.3Å; M108-M260 HydrophobicContact CG-CB 3.63Å; M108-M260 HydrophobicContact CG-CG 4.28Å
109	I	98.6	Very high	97.3	Very high	9 Å²	9	39.9 Å²	39.9	5%	0.046	22%	0.215	C	C	.	.	H	α-helix	trans	-58.7	-46.3	173.4	-68.5	159.7	0	0	0	109.4	L67 I105 C106 G112 F113 T253 F257	L67-I109 HydrophobicContact CD1-CD1 3.85Å; L67-I109 HydrophobicContact CD2-CD1 4.22Å; L67-I109 HydrophobicContact CG-CD1 3.88Å; I105-I109 HydrophobicContact CG2-CD1 3.87Å; I105-I109 HydrophobicContact CG2-CG1 4.41Å; I105-I109 WeakPolarHBondContact O-CG1 2.94Å; I105-I109 PolarHBondContact O-N 2.9Å; C106-I109 PolarHBondContact O-N 3.34Å; I109-G112 PolarHBondContact O-N 3.01Å; I109-F113 WeakPolarHBondContact O-CB 3.33Å; I109-F113 PolarHBondContact O-N 2.95Å; I109-T253 HydrophobicContact CG2-CG2 4.24Å; I109-F257 HydrophobicContact CD1-CD2 3.73Å; I109-F257 HydrophobicContact CD1-CE2 4.13Å; I109-F257 HydrophobicContact CD1-CG 4.25Å; I109-F257 HydrophobicContact CG1-CB 3.77Å; I109-F257 HydrophobicContact CG1-CD2 3.71Å; I109-F257 HydrophobicContact CG1-CG 3.87Å
110	F	98.2	Very high	97.1	Very high	132 Å²	132	39 Å²	39	58%	0.579	21%	0.211	S	C	*	.	H	α-helix	trans	-60.5	-49	177.4	170.2	-108.5	0	0	0	112.4	C106 C107 M108 F113 A114	C106-F110 WeakPolarHBondContact O-CB 3.48Å; C106-F110 PolarHBondContact O-N 2.88Å; C107-F110 PolarHBondContact O-N 3.05Å; M108-F110 VanDerWaalsContact C-N 3.29Å; M108-F110 PolarHBondContact O-N 3.5Å; F110-F113 PolarHBondContact O-N 3.17Å; F110-A114 WeakPolarHBondContact O-CB 3.12Å; F110-A114 PolarHBondContact O-N 2.91Å
111	L	96.2	Very high	96.9	Very high	23 Å²	23	46.6 Å²	46.6	12%	0.12	24%	0.237	C	C	.	.	H	α-helix	trans	-68.5	-35.3	-178.8	-69.1	175.4	0	0	0	112.7	C107 M108 A114 D115 L128 A132	C107-L111 WeakPolarHBondContact O-CB 3.34Å; C107-L111 VanDerWaalsContact O-CG 3.23Å; C107-L111 WeakPolarHBondContact O-CG 3.47Å; C107-L111 PolarHBondContact O-N 3.4Å; M108-L111 PolarHBondContact O-N 2.83Å; L111-A114 PolarHBondContact O-N 3.06Å; L111-D115 WeakPolarHBondContact O-CB 3.37Å; L111-D115 PolarHBondContact O-N 3.47Å; L111-L128 HydrophobicContact CB-CD1 4.46Å; L111-L128 HydrophobicContact CD1-CB 3.97Å; L111-L128 HydrophobicContact CD1-CD2 4.23Å; L111-L128 HydrophobicContact CD2-CD1 4.31Å; L111-L128 HydrophobicContact CD2-CD2 3.96Å; L111-A132 HydrophobicContact CD1-CB 3.92Å
112	G	97.3	Very high	96.4	Very high	0 Å²	0	55.6 Å²	55.6	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-65.5	-40.8	173.2	0	0	0	0	0	112	M108 I109 D115 D116	M108-G112 PolarHBondContact O-N 2.8Å; I109-G112 PolarHBondContact O-N 3.01Å; G112-D115 WeakPolarHBondContact O-CB 3.28Å; G112-D115 PolarHBondContact O-N 2.9Å; G112-D116 PolarHBondContact O-N 3.35Å
113	F	98.1	Very high	96.1	Very high	63 Å²	63	61.1 Å²	61.1	28%	0.276	29%	0.292	S	S	.	.	H	α-helix	trans	-66.1	-39.7	173.4	-174.3	-109	0	0	0	112.4	F36 L41 V60 I109 F110 D115 D116 V117 T253	F36-F113 HydrophobicContact CE1-CE2 4.42Å; L41-F113 HydrophobicContact CD1-CE2 3.88Å; L41-F113 HydrophobicContact CD1-CZ 3.9Å; V60-F113 HydrophobicContact CB-CD2 3.85Å; V60-F113 HydrophobicContact CB-CE2 4.32Å; V60-F113 HydrophobicContact CB-CG 4.46Å; V60-F113 HydrophobicContact CG1-CD2 4.17Å; V60-F113 HydrophobicContact CG1-CE2 4.13Å; V60-F113 HydrophobicContact CG2-CB 4.23Å; V60-F113 HydrophobicContact CG2-CD2 3.8Å; V60-F113 HydrophobicContact CG2-CE2 4.32Å; V60-F113 HydrophobicContact CG2-CG 3.96Å; I109-F113 WeakPolarHBondContact O-CB 3.33Å; I109-F113 PolarHBondContact O-N 2.95Å; F110-F113 PolarHBondContact O-N 3.17Å; F113-D115 VanDerWaalsContact C-N 3.3Å; F113-D115 PolarHBondContact O-N 3.27Å; F113-D116 PolarHBondContact O-N 3Å; F113-V117 HydrophobicContact CD1-CG2 4.28Å; F113-V117 HydrophobicContact CE1-CG2 3.91Å; F113-V117 HydrophobicContact CE2-CG2 4.21Å; F113-V117 HydrophobicContact CZ-CG2 3.88Å; F113-V117 VanDerWaalsContact O-CG2 3.24Å; F113-V117 WeakPolarHBondContact O-CG2 3.48Å; F113-V117 PolarHBondContact O-N 3.44Å; F113-T253 WeakPolarHBondContact CA-OG1 3.41Å; F113-T253 HydrophobicContact CB-CG2 4.15Å; F113-T253 PolarHBondContact N-OG1 2.79Å
114	A	97.3	Very high	95.8	Very high	21 Å²	21	58.9 Å²	58.9	17%	0.174	28%	0.278	C	S	.	.	H	α-helix	trans	-62.1	-37.7	172.7	0	0	0	0	0	112	F110 L111 V117 L118	F110-A114 WeakPolarHBondContact O-CB 3.12Å; F110-A114 PolarHBondContact O-N 2.91Å; L111-A114 PolarHBondContact O-N 3.06Å; A114-V117 PolarHBondContact O-N 2.8Å; A114-L118 WeakPolarHBondContact O-CB 3.26Å; A114-L118 VanDerWaalsContact O-CG 3.25Å; A114-L118 WeakPolarHBondContact O-CG 3.38Å; A114-L118 PolarHBondContact O-N 3.01Å
115	D	95.7	Very high	95.4	Very high	1 Å²	1	60.8 Å²	60.8	1%	0.005	29%	0.287	C	S	.	.	H	α-helix	trans	-65.8	-43.9	175.8	-166.6	18.6	0	0	0	112	L111 G112 F113 V117 L118 N119 L120 K125 Y256	L111-D115 WeakPolarHBondContact O-CB 3.37Å; L111-D115 PolarHBondContact O-N 3.47Å; G112-D115 WeakPolarHBondContact O-CB 3.28Å; G112-D115 PolarHBondContact O-N 2.9Å; F113-D115 VanDerWaalsContact C-N 3.3Å; F113-D115 PolarHBondContact O-N 3.27Å; D115-V117 VanDerWaalsContact C-N 3.34Å; D115-V117 PolarHBondContact O-N 3.18Å; D115-L118 PolarHBondContact O-N 2.91Å; D115-N119 WeakPolarHBondContact O-CA 3.34Å; D115-N119 PolarHBondContact O-N 3.4Å; D115-L120 HydrophobicContact CB-CD1 4.26Å; D115-L120 VanDerWaalsContact OD1-CB 3.23Å; D115-L120 WeakPolarHBondContact OD1-CB 3.22Å; D115-L120 PolarHBondContact OD1-N 3.13Å; D115-K125 IonicContact OD1-NZ 3.83Å; D115-K125 WeakPolarHBondContact OD2-CE 3.41Å; D115-K125 IonicContact OD2-NZ 2.89Å; D115-K125 PolarHBondContact OD2-NZ 3.49Å; D115-Y256 HydrophobicContact CB-CE2 4.4Å; D115-Y256 PolarHBondContact OD2-OH 2.8Å
116	D	96.4	Very high	95.1	Very high	21 Å²	21	64.4 Å²	64.4	11%	0.112	31%	0.306	C	S	.	.	H	α-helix	trans	-59.7	-43.1	175	-83	-32.2	0	0	0	112.3	S57 G112 F113 G251 D252 T253	S57-D116 WeakPolarHBondContact CB-OD2 3.46Å; S57-D116 WeakPolarHBondContact OG-CB 3.36Å; S57-D116 PolarHBondContact OG-OD2 3.47Å; G112-D116 PolarHBondContact O-N 3.35Å; F113-D116 PolarHBondContact O-N 3Å; D116-G251 WeakPolarHBondContact OD2-CA 3.44Å; D116-D252 VanDerWaalsContact OD1-CB 3.28Å; D116-D252 WeakPolarHBondContact OD1-CB 3.47Å; D116-D252 PolarHBondContact OD1-N 3.24Å; D116-D252 PolarHBondContact OD2-N 2.62Å; D116-T253 WeakPolarHBondContact OD2-CB 3.37Å; D116-T253 PolarHBondContact OD2-N 3.23Å; D116-T253 PolarHBondContact OD2-OG1 3.24Å
117	V	96.8	Very high	94.8	Very high	70 Å²	70	67.5 Å²	67.5	42%	0.424	32%	0.318	S	S	.	.	H	α-helix	trans	-72.9	-44.2	-178.8	175.1	0	0	0	0	111.4	L41 F113 A114 D115	L41-V117 HydrophobicContact CD1-CG2 4.24Å; L41-V117 HydrophobicContact CD2-CG2 3.91Å; F113-V117 HydrophobicContact CD1-CG2 4.28Å; F113-V117 HydrophobicContact CE1-CG2 3.91Å; F113-V117 HydrophobicContact CE2-CG2 4.21Å; F113-V117 HydrophobicContact CZ-CG2 3.88Å; F113-V117 VanDerWaalsContact O-CG2 3.24Å; F113-V117 WeakPolarHBondContact O-CG2 3.48Å; F113-V117 PolarHBondContact O-N 3.44Å; A114-V117 PolarHBondContact O-N 2.8Å; D115-V117 VanDerWaalsContact C-N 3.34Å; D115-V117 PolarHBondContact O-N 3.18Å
118	L	95.7	Very high	94.3	Very high	116 Å²	116	67.2 Å²	67.2	61%	0.607	31%	0.314	S	S	*	.	H	α-helix	trans	-95.7	-10.8	-170.4	-58.1	176	0	0	0	113.7	A114 D115 L120	A114-L118 WeakPolarHBondContact O-CB 3.26Å; A114-L118 VanDerWaalsContact O-CG 3.25Å; A114-L118 WeakPolarHBondContact O-CG 3.38Å; A114-L118 PolarHBondContact O-N 3.01Å; D115-L118 PolarHBondContact O-N 2.91Å; L118-L120 HydrophobicContact CB-CD2 3.77Å; L118-L120 HydrophobicContact CB-CG 4.23Å; L118-L120 HydrophobicContact CD1-CD2 4.26Å
119	N	92.7	Very high	94.1	Very high	115 Å²	115	67.2 Å²	67.2	62%	0.615	31%	0.314	S	S	*	.	T	Hydrogen-bonded Turn	trans	49.2	63.7	-175.3	-72.6	-89.3	0	0	0	112.1	D115	D115-N119 WeakPolarHBondContact O-CA 3.34Å; D115-N119 PolarHBondContact O-N 3.4Å
120	L	92.2	Very high	93.9	Very high	47 Å²	47	69.6 Å²	69.6	25%	0.246	33%	0.329	C	S	.	.			trans	-69.2	152.3	-171.1	-57.2	174.2	0	0	0	112.1	D115 L118 H124 L128	D115-L120 HydrophobicContact CB-CD1 4.26Å; D115-L120 VanDerWaalsContact OD1-CB 3.23Å; D115-L120 WeakPolarHBondContact OD1-CB 3.22Å; D115-L120 PolarHBondContact OD1-N 3.13Å; L118-L120 HydrophobicContact CB-CD2 3.77Å; L118-L120 HydrophobicContact CB-CG 4.23Å; L118-L120 HydrophobicContact CD1-CD2 4.26Å; L120-H124 HydrophobicContact CB-CB 4.04Å; L120-H124 HydrophobicContact CD1-CB 4.15Å; L120-L128 HydrophobicContact CD1-CD1 3.51Å
121	R	92.8	Very high	93.6	Very high	169 Å²	169	65.8 Å²	65.8	64%	0.638	32%	0.322	S	S	*	.			trans	-63.3	149.1	174	-59.1	-177	-173.5	-177.8	2	111.1	R123 H124	R121-R123 HydrophobicContact CB-CG 4.31Å; R121-R123 PolarHBondContact O-N 3.33Å; R121-H124 PolarHBondContact N-ND1 2.91Å; R121-H124 PolarHBondContact O-N 3.45Å; R121-H124 PolarHBondContact O-ND1 2.68Å
122	W	88.5	Confident	93.6	Very high	189 Å²	189	64.7 Å²	64.7	72%	0.716	32%	0.316	S	S	*	.	H	α-helix	trans	-46.7	-36	-178.1	71.2	-94.2	0	0	0	114.9	H124 K125 L126	W122-H124 VanDerWaalsContact C-N 3.25Å; W122-H124 PolarHBondContact O-N 3.47Å; W122-K125 WeakPolarHBondContact O-CA 3.2Å; W122-K125 VanDerWaalsContact O-CB 3.31Å; W122-K125 WeakPolarHBondContact O-CB 3.35Å; W122-K125 PolarHBondContact O-N 2.94Å; W122-L126 HydrophobicContact CE3-CD1 3.94Å; W122-L126 HydrophobicContact CZ3-CD1 3.68Å
123	R	91.3	Very high	93.5	Very high	121 Å²	121	64.8 Å²	64.8	46%	0.457	32%	0.317	S	S	.	.	H	α-helix	trans	-57.4	-37	177.3	67.4	-175.7	-177.9	-167.9	-0.6	113	R121 K125 L126 L127	R121-R123 HydrophobicContact CB-CG 4.31Å; R121-R123 PolarHBondContact O-N 3.33Å; R123-K125 VanDerWaalsContact C-N 3.31Å; R123-L126 PolarHBondContact O-N 3.22Å; R123-L127 WeakPolarHBondContact O-CG 3.35Å; R123-L127 PolarHBondContact O-N 3.11Å
124	H	91.8	Very high	93.4	Very high	51 Å²	51	66.1 Å²	66.1	24%	0.236	33%	0.327	C	S	.	.	H	α-helix	trans	-73.9	-27.7	179.1	-48.6	108.4	0	0	0	111	L120 R121 W122 L126 L127 L128	L120-H124 HydrophobicContact CB-CB 4.04Å; L120-H124 HydrophobicContact CD1-CB 4.15Å; R121-H124 PolarHBondContact N-ND1 2.91Å; R121-H124 PolarHBondContact O-N 3.45Å; R121-H124 PolarHBondContact O-ND1 2.68Å; W122-H124 VanDerWaalsContact C-N 3.25Å; W122-H124 PolarHBondContact O-N 3.47Å; H124-L126 PolarHBondContact O-N 2.85Å; H124-L126 VanDerWaalsContact O-N 3.14Å; H124-L127 PolarHBondContact O-N 3.39Å; H124-L128 HydrophobicContact CB-CD1 4.09Å; H124-L128 HydrophobicContact CB-CG 4.18Å; H124-L128 WeakPolarHBondContact O-CB 3.21Å; H124-L128 VanDerWaalsContact O-CG 3.24Å; H124-L128 WeakPolarHBondContact O-CG 3.39Å; H124-L128 PolarHBondContact O-N 3.23Å
125	K	90.4	Very high	93.3	Very high	41 Å²	41	66.5 Å²	66.5	18%	0.178	33%	0.327	C	S	.	.	H	α-helix	trans	-64.8	-13.7	172.1	-51.1	-164.7	173.7	-106.9	0	113.2	D115 W122 R123 P129 N182 D252 Y256	D115-K125 IonicContact OD1-NZ 3.83Å; D115-K125 WeakPolarHBondContact OD2-CE 3.41Å; D115-K125 IonicContact OD2-NZ 2.89Å; D115-K125 PolarHBondContact OD2-NZ 3.49Å; W122-K125 WeakPolarHBondContact O-CA 3.2Å; W122-K125 VanDerWaalsContact O-CB 3.31Å; W122-K125 WeakPolarHBondContact O-CB 3.35Å; W122-K125 PolarHBondContact O-N 2.94Å; R123-K125 VanDerWaalsContact C-N 3.31Å; K125-P129 WeakPolarHBondContact O-CD 3.23Å; K125-P129 WeakPolarHBondContact O-CG 3.16Å; K125-N182 PolarHBondContact O-ND2 3.49Å; K125-D252 IonicContact NZ-OD1 2.74Å; K125-D252 IonicContact NZ-OD2 3.69Å; K125-D252 PolarHBondContact NZ-OD2 3.02Å; K125-Y256 WeakPolarHBondContact CB-OH 3.32Å; K125-Y256 WeakPolarHBondContact CG-OH 3.32Å
126	L	91.9	Very high	93.2	Very high	76 Å²	76	66.5 Å²	66.5	40%	0.398	33%	0.327	S	S	.	.	H	α-helix	trans	-99.8	-44.9	171.2	-56.3	178.4	0	0	0	112.1	W122 R123 H124 T130 V178	W122-L126 HydrophobicContact CE3-CD1 3.94Å; W122-L126 HydrophobicContact CZ3-CD1 3.68Å; R123-L126 PolarHBondContact O-N 3.22Å; H124-L126 PolarHBondContact O-N 2.85Å; H124-L126 VanDerWaalsContact O-N 3.14Å; L126-T130 PolarHBondContact O-N 2.73Å; L126-T130 PolarHBondContact O-OG1 3.12Å; L126-V178 HydrophobicContact CD2-CG1 3.71Å
127	L	92.6	Very high	93.2	Very high	110 Å²	110	66.3 Å²	66.3	58%	0.576	33%	0.326	S	S	*	.	H	α-helix	trans	-70.2	-40.5	-176.9	-66.8	171.8	0	0	0	113	R123 H124 T130 A131	R123-L127 WeakPolarHBondContact O-CG 3.35Å; R123-L127 PolarHBondContact O-N 3.11Å; H124-L127 PolarHBondContact O-N 3.39Å; L127-T130 WeakPolarHBondContact O-CB 3.31Å; L127-T130 PolarHBondContact O-N 2.7Å; L127-A131 PolarHBondContact O-N 3.02Å
128	L	89.1	Confident	93.1	Very high	37 Å²	37	68 Å²	68	19%	0.194	33%	0.331	C	S	.	.	H	α-helix	trans	-66.4	-46.5	-176.2	-67.6	-180	0	0	0	112.2	L111 L120 H124 T130 A131 A132	L111-L128 HydrophobicContact CB-CD1 4.46Å; L111-L128 HydrophobicContact CD1-CB 3.97Å; L111-L128 HydrophobicContact CD1-CD2 4.23Å; L111-L128 HydrophobicContact CD2-CD1 4.31Å; L111-L128 HydrophobicContact CD2-CD2 3.96Å; L120-L128 HydrophobicContact CD1-CD1 3.51Å; H124-L128 HydrophobicContact CB-CD1 4.09Å; H124-L128 HydrophobicContact CB-CG 4.18Å; H124-L128 WeakPolarHBondContact O-CB 3.21Å; H124-L128 VanDerWaalsContact O-CG 3.24Å; H124-L128 WeakPolarHBondContact O-CG 3.39Å; H124-L128 PolarHBondContact O-N 3.23Å; L128-T130 VanDerWaalsContact C-N 3.27Å; L128-T130 PolarHBondContact O-N 3.33Å; L128-A131 PolarHBondContact O-N 3.44Å; L128-A132 WeakPolarHBondContact O-CB 3.33Å; L128-A132 PolarHBondContact O-N 2.89Å
129	P	91.8	Very high	93.1	Very high	0 Å²	0	62.9 Å²	62.9	0%	0	30%	0.304	C	S	.	.	H	α-helix	trans	-60.6	-35.9	171.8	-28.2	37.9	0	0	0	114.2	M108 K125 A132 S133 V178	M108-P129 VanDerWaalsContact CE-CA 3.44Å; M108-P129 HydrophobicContact CE-CB 3.59Å; M108-P129 HydrophobicContact CE-CG 3.93Å; M108-P129 HydrophobicContact SD-CG 4.49Å; K125-P129 WeakPolarHBondContact O-CD 3.23Å; K125-P129 WeakPolarHBondContact O-CG 3.16Å; P129-A132 PolarHBondContact O-N 3.49Å; P129-S133 WeakPolarHBondContact O-CB 3.37Å; P129-S133 PolarHBondContact O-N 2.81Å; P129-S133 PolarHBondContact O-OG 3.28Å; P129-V178 HydrophobicContact CB-CB 4.35Å; P129-V178 HydrophobicContact CB-CG2 3.87Å
130	T	94.4	Very high	93.2	Very high	58 Å²	58	57.5 Å²	57.5	36%	0.356	28%	0.275	S	S	.	.	H	α-helix	trans	-61.1	-49.5	175.4	-54.4	0	0	0	0	110.3	L126 L127 L128 S133 V178	L126-T130 PolarHBondContact O-N 2.73Å; L126-T130 PolarHBondContact O-OG1 3.12Å; L127-T130 WeakPolarHBondContact O-CB 3.31Å; L127-T130 PolarHBondContact O-N 2.7Å; L128-T130 VanDerWaalsContact C-N 3.27Å; L128-T130 PolarHBondContact O-N 3.33Å; T130-S133 PolarHBondContact O-N 2.95Å; T130-S133 PolarHBondContact O-OG 3.04Å; T130-V178 VanDerWaalsContact OG1-CG2 3.26Å; T130-V178 WeakPolarHBondContact OG1-CG2 3.31Å
131	A	93.8	Very high	93.3	Very high	52 Å²	52	61.5 Å²	61.5	43%	0.43	29%	0.291	S	S	.	.	H	α-helix	trans	-64.5	-43.4	178.4	0	0	0	0	0	112.7	L127 L128 S133 L134	L127-A131 PolarHBondContact O-N 3.02Å; L128-A131 PolarHBondContact O-N 3.44Å; A131-S133 PolarHBondContact O-N 3.17Å; A131-L134 WeakPolarHBondContact O-CB 3.13Å; A131-L134 VanDerWaalsContact O-CG 3.31Å; A131-L134 WeakPolarHBondContact O-CG 3.47Å; A131-L134 PolarHBondContact O-N 3.07Å; A131-L134 VanDerWaalsContact O-N 3.14Å
132	A	94.9	Very high	93.3	Very high	1 Å²	1	58 Å²	58	1%	0.008	29%	0.288	C	S	.	.	H	α-helix	trans	-67.2	-20.2	177.9	0	0	0	0	0	113.5	A104 C107 M108 L111 L128 P129 P135 M260	A104-A132 WeakPolarHBondContact CA-O 3.11Å; A104-A132 WeakPolarHBondContact CB-O 3.49Å; C107-A132 HydrophobicContact CB-CB 4.2Å; M108-A132 HydrophobicContact CE-CB 4.03Å; L111-A132 HydrophobicContact CD1-CB 3.92Å; L128-A132 WeakPolarHBondContact O-CB 3.33Å; L128-A132 PolarHBondContact O-N 2.89Å; P129-A132 PolarHBondContact O-N 3.49Å; A132-P135 WeakPolarHBondContact O-CD 3.31Å; A132-M260 HydrophobicContact CB-CE 4.07Å
133	S	95.1	Very high	93.3	Very high	1 Å²	1	51.4 Å²	51.4	1%	0.007	27%	0.267	C	S	.	.	T	Hydrogen-bonded Turn	trans	-80.2	-12.4	174.2	75.6	0	0	0	0	113.7	P129 T130 A131 P135 L136 L137	P129-S133 WeakPolarHBondContact O-CB 3.37Å; P129-S133 PolarHBondContact O-N 2.81Å; P129-S133 PolarHBondContact O-OG 3.28Å; T130-S133 PolarHBondContact O-N 2.95Å; T130-S133 PolarHBondContact O-OG 3.04Å; A131-S133 PolarHBondContact O-N 3.17Å; S133-P135 VanDerWaalsContact C-CD 3.49Å; S133-L136 WeakPolarHBondContact O-CA 3.35Å; S133-L136 WeakPolarHBondContact O-CB 3.47Å; S133-L136 PolarHBondContact O-N 2.9Å; S133-L137 WeakPolarHBondContact O-CD1 3.28Å; S133-L137 PolarHBondContact O-N 2.86Å; S133-L137 VanDerWaalsContact O-N 3.13Å
134	L	96	Very high	93.2	Very high	92 Å²	92	49.4 Å²	49.4	48%	0.482	26%	0.262	S	S	.	.	H	α-helix	trans	-56.8	-41.7	-177	-67.3	174.7	0	0	0	114.3	A131 L136 L137 M138	A131-L134 WeakPolarHBondContact O-CB 3.13Å; A131-L134 VanDerWaalsContact O-CG 3.31Å; A131-L134 WeakPolarHBondContact O-CG 3.47Å; A131-L134 PolarHBondContact O-N 3.07Å; A131-L134 VanDerWaalsContact O-N 3.14Å; L134-L136 PolarHBondContact O-N 3.49Å; L134-L137 PolarHBondContact O-N 3.16Å; L134-L137 VanDerWaalsContact O-N 3.17Å; L134-M138 WeakPolarHBondContact O-CG 3.44Å; L134-M138 PolarHBondContact O-N 3.15Å
135	P	96.1	Very high	92.8	Very high	29 Å²	29	48.7 Å²	48.7	19%	0.188	27%	0.268	C	S	.	.	H	α-helix	trans	-55.8	-39.8	173.9	-25.6	35.4	0	0	0	112.8	L103 A104 A132 S133 M138 V139	L103-P135 HydrophobicContact CB-CB 4.38Å; L103-P135 HydrophobicContact CD2-CB 4Å; L103-P135 HydrophobicContact CD2-CG 3.85Å; L103-P135 HydrophobicContact CG-CB 4.2Å; L103-P135 HydrophobicContact CG-CG 3.9Å; A104-P135 HydrophobicContact CB-CB 4.4Å; A132-P135 WeakPolarHBondContact O-CD 3.31Å; S133-P135 VanDerWaalsContact C-CD 3.49Å; P135-M138 PolarHBondContact O-N 2.94Å; P135-V139 WeakPolarHBondContact O-CG2 3.46Å; P135-V139 PolarHBondContact O-N 3.25Å
136	L	93.8	Very high	92.8	Very high	0 Å²	0	51 Å²	51	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-63.5	-45.4	177.7	-172.1	66.2	0	0	0	111.4	S133 L134 M138 V139 Y140 V264 I267 L268	S133-L136 WeakPolarHBondContact O-CA 3.35Å; S133-L136 WeakPolarHBondContact O-CB 3.47Å; S133-L136 PolarHBondContact O-N 2.9Å; L134-L136 PolarHBondContact O-N 3.49Å; L136-M138 VanDerWaalsContact C-N 3.33Å; L136-M138 PolarHBondContact O-N 2.9Å; L136-V139 PolarHBondContact O-N 3.14Å; L136-Y140 WeakPolarHBondContact O-CB 3.25Å; L136-Y140 PolarHBondContact O-N 3.25Å; L136-V264 HydrophobicContact CD1-CB 4.31Å; L136-V264 HydrophobicContact CD1-CG1 4.35Å; L136-V264 HydrophobicContact CD1-CG2 3.98Å; L136-V264 HydrophobicContact CD2-CG2 4.13Å; L136-I267 HydrophobicContact CD1-CG2 4.36Å; L136-I267 HydrophobicContact CD2-CB 4.04Å; L136-I267 HydrophobicContact CD2-CD1 3.38Å; L136-I267 HydrophobicContact CD2-CG1 4.27Å; L136-I267 HydrophobicContact CD2-CG2 4.16Å; L136-I267 HydrophobicContact CG-CB 4.41Å; L136-I267 HydrophobicContact CG-CD1 4.37Å; L136-I267 HydrophobicContact CG-CG2 4.05Å; L136-L268 HydrophobicContact CD1-CD1 3.57Å; L136-L268 HydrophobicContact CD1-CD2 3.87Å; L136-L268 HydrophobicContact CD1-CG 3.47Å; L136-L268 VanDerWaalsContact CD1-CG 3.47Å
137	L	95.2	Very high	92.9	Very high	17 Å²	17	48.3 Å²	48.3	9%	0.089	27%	0.269	C	S	.	.	H	α-helix	trans	-63.5	-39.3	177.1	-87.1	63.3	0	0	0	111.4	S133 L134 Y140 F141 Y170 M173	S133-L137 WeakPolarHBondContact O-CD1 3.28Å; S133-L137 PolarHBondContact O-N 2.86Å; S133-L137 VanDerWaalsContact O-N 3.13Å; L134-L137 PolarHBondContact O-N 3.16Å; L134-L137 VanDerWaalsContact O-N 3.17Å; L137-Y140 PolarHBondContact O-N 3.47Å; L137-F141 WeakPolarHBondContact O-CB 3.45Å; L137-F141 PolarHBondContact O-N 3.46Å; L137-Y170 HydrophobicContact CB-CD1 4.18Å; L137-Y170 HydrophobicContact CD2-CD1 4.34Å; L137-Y170 HydrophobicContact CG-CD1 4.05Å; L137-M173 HydrophobicContact CD1-CB 3.89Å; L137-M173 HydrophobicContact CG-CB 4.4Å; L137-M173 HydrophobicContact CG-CE 4.29Å
138	M	96	Very high	92.9	Very high	107 Å²	107	45.8 Å²	45.8	53%	0.527	26%	0.259	S	S	.	.	H	α-helix	trans	-67.4	-44.6	177.9	-66.5	-58.5	97.8	0	0	111.8	L134 P135 L136 Y140 F141 T142	L134-M138 WeakPolarHBondContact O-CG 3.44Å; L134-M138 PolarHBondContact O-N 3.15Å; P135-M138 PolarHBondContact O-N 2.94Å; L136-M138 VanDerWaalsContact C-N 3.33Å; L136-M138 PolarHBondContact O-N 2.9Å; M138-Y140 VanDerWaalsContact C-N 3.29Å; M138-Y140 PolarHBondContact O-N 2.88Å; M138-F141 PolarHBondContact O-N 2.85Å; M138-T142 WeakPolarHBondContact O-CG2 3.42Å; M138-T142 PolarHBondContact O-N 3.33Å; M138-T142 PolarHBondContact O-OG1 3.37Å
139	V	95.1	Very high	93.1	Very high	8 Å²	8	46 Å²	46	5%	0.048	26%	0.26	C	S	.	.	H	α-helix	trans	-57.8	-45.1	173	168	0	0	0	0	110.7	V96 A97 P135 L136 F141 T142 N143 L268	V96-V139 HydrophobicContact CG1-CG2 4.04Å; A97-V139 HydrophobicContact CB-CG1 4.04Å; P135-V139 WeakPolarHBondContact O-CG2 3.46Å; P135-V139 PolarHBondContact O-N 3.25Å; L136-V139 PolarHBondContact O-N 3.14Å; V139-F141 VanDerWaalsContact C-N 3.31Å; V139-F141 PolarHBondContact O-N 3.14Å; V139-T142 PolarHBondContact O-N 3.44Å; V139-T142 PolarHBondContact O-OG1 2.96Å; V139-N143 WeakPolarHBondContact O-CB 3.46Å; V139-N143 PolarHBondContact O-N 2.88Å; V139-L268 HydrophobicContact CB-CD2 4.44Å; V139-L268 HydrophobicContact CG1-CD1 4.29Å; V139-L268 HydrophobicContact CG1-CD2 3.72Å
140	Y	94.4	Very high	93	Very high	2 Å²	2	48.7 Å²	48.7	1%	0.008	28%	0.276	C	S	.	.	H	α-helix	trans	-60.2	-44	179.5	-165.6	-87.5	0	0	0	111.8	L136 L137 M138 F144 G145 N146 Y169 Y170 M173 I267 H270	L136-Y140 WeakPolarHBondContact O-CB 3.25Å; L136-Y140 PolarHBondContact O-N 3.25Å; L137-Y140 PolarHBondContact O-N 3.47Å; M138-Y140 VanDerWaalsContact C-N 3.29Å; M138-Y140 PolarHBondContact O-N 2.88Å; Y140-F144 HydrophobicContact CD2-CD2 4.21Å; Y140-F144 HydrophobicContact CE2-CB 4.37Å; Y140-F144 PolarHBondContact O-N 3.45Å; Y140-F144 VanDerWaalsContact O-N 3.09Å; Y140-G145 PolarHBondContact O-N 2.95Å; Y140-N146 PolarHBondContact OH-O 3.5Å; Y140-Y169 HydrophobicContact CD1-CE1 4.5Å; Y140-Y169 HydrophobicContact CE1-CD1 4.03Å; Y140-Y169 AromaticContact CE1-CE1 3.66Å; Y140-Y169 HydrophobicContact CE1-CE1 3.66Å; Y140-Y169 HydrophobicContact CE2-CE1 4.24Å; Y140-Y169 AromaticContact CZ-CE1 3.5Å; Y140-Y169 VanDerWaalsContact CZ-CE1 3.5Å; Y140-Y169 WeakPolarHBondContact OH-CE1 3.38Å; Y140-Y169 PolarHBondContact OH-OH 3.39Å; Y140-Y170 HydrophobicContact CD1-CE1 4.27Å; Y140-M173 HydrophobicContact CD1-CE 3.65Å; Y140-M173 HydrophobicContact CD1-SD 3.97Å; Y140-M173 HydrophobicContact CD2-SD 3.81Å; Y140-M173 HydrophobicContact CE1-CE 4.23Å; Y140-M173 HydrophobicContact CE1-SD 4.33Å; Y140-M173 HydrophobicContact CE2-SD 4.17Å; Y140-M173 HydrophobicContact CG-CE 3.82Å; Y140-M173 HydrophobicContact CG-SD 3.68Å; Y140-I267 HydrophobicContact CD2-CG2 3.88Å; Y140-I267 HydrophobicContact CE2-CG2 4.39Å; Y140-H270 AromaticContact CE2-CE1 3.49Å; Y140-H270 VanDerWaalsContact CE2-CE1 3.49Å; Y140-H270 WeakPolarHBondContact CE2-CE1 3.23Å; Y140-H270 AromaticContact CZ-CE1 3.91Å
141	F	94.6	Very high	92.9	Very high	131 Å²	131	46.1 Å²	46.1	58%	0.575	26%	0.26	S	S	*	.	H	α-helix	trans	-62.7	-44	178	176.6	-102.1	0	0	0	112.8	L137 M138 V139 Y170	L137-F141 WeakPolarHBondContact O-CB 3.45Å; L137-F141 PolarHBondContact O-N 3.46Å; M138-F141 PolarHBondContact O-N 2.85Å; V139-F141 VanDerWaalsContact C-N 3.31Å; V139-F141 PolarHBondContact O-N 3.14Å; F141-Y170 VanDerWaalsContact CA-OH 3.29Å; F141-Y170 WeakPolarHBondContact CA-OH 3.43Å; F141-Y170 HydrophobicContact CB-CE1 3.91Å; F141-Y170 WeakPolarHBondContact CD2-OH 3.29Å
142	T	92.3	Very high	92.6	Very high	94 Å²	94	45.1 Å²	45.1	58%	0.577	25%	0.249	S	C	*	.	H	α-helix	trans	-78.4	-29.6	-175.9	56.8	0	0	0	0	113.9	M138 V139	M138-T142 WeakPolarHBondContact O-CG2 3.42Å; M138-T142 PolarHBondContact O-N 3.33Å; M138-T142 PolarHBondContact O-OG1 3.37Å; V139-T142 PolarHBondContact O-N 3.44Å; V139-T142 PolarHBondContact O-OG1 2.96Å
143	N	88.9	Confident	92.3	Very high	51 Å²	51	48.5 Å²	48.5	27%	0.273	26%	0.264	S	S	.	.	H	α-helix	trans	-105.2	-37.8	-169.2	-67.5	22	0	0	0	113.9	H93 V139	H93-N143 PolarHBondContact O-ND2 2.9Å; V139-N143 WeakPolarHBondContact O-CB 3.46Å; V139-N143 PolarHBondContact O-N 2.88Å
144	F	88.1	Confident	92	Very high	79 Å²	79	52.5 Å²	52.5	35%	0.346	29%	0.289	S	S	.	.	T	Hydrogen-bonded Turn	trans	-117.1	-51.3	-171.5	-55.6	-79.8	0	0	0	112	Y140 N146 L268 H270	Y140-F144 HydrophobicContact CD2-CD2 4.21Å; Y140-F144 HydrophobicContact CE2-CB 4.37Å; Y140-F144 PolarHBondContact O-N 3.45Å; Y140-F144 VanDerWaalsContact O-N 3.09Å; F144-N146 PolarHBondContact O-N 2.64Å; F144-L268 HydrophobicContact CE2-CD2 4.04Å; F144-H270 AromaticContact CD1-CE1 3.95Å; F144-H270 AromaticContact CD1-NE2 3.22Å; F144-H270 WeakPolarHBondContact CD1-NE2 3.42Å; F144-H270 AromaticContact CE1-NE2 3.48Å; F144-H270 WeakPolarHBondContact CE1-NE2 3.46Å; F144-H270 AromaticContact CG-CE1 3.88Å; F144-H270 AromaticContact CG-NE2 3.51Å; F144-H270 AromaticContact CZ-NE2 3.98Å
145	G	83.6	Confident	91.7	Very high	36 Å²	36	53.6 Å²	53.6	37%	0.371	29%	0.291	S	S	.	.			trans	64.3	1	174.7	0	0	0	0	0	116.3	Y140 T147	Y140-G145 PolarHBondContact O-N 2.95Å; G145-T147 PolarHBondContact O-N 3Å
146	N	90.8	Very high	91.5	Very high	89 Å²	89	54.6 Å²	54.6	48%	0.476	29%	0.291	S	S	.	.			trans	-79.7	104.2	-175.4	-173.6	9.4	0	0	0	112.1	Y140 F144 T148	Y140-N146 PolarHBondContact OH-O 3.5Å; F144-N146 PolarHBondContact O-N 2.64Å; N146-T148 WeakPolarHBondContact OD1-CB 3.49Å; N146-T148 PolarHBondContact OD1-N 3.18Å
147	T	93.6	Very high	91.5	Very high	21 Å²	21	60.1 Å²	60.1	13%	0.129	33%	0.327	C	S	.	.			trans	-96.6	3.3	178	51.7	0	0	0	0	113.8	G145 D164 L165 Y169 Y170	G145-T147 PolarHBondContact O-N 3Å; T147-D164 WeakPolarHBondContact CB-OD1 3.46Å; T147-D164 PolarHBondContact OG1-OD1 2.92Å; T147-L165 PolarHBondContact O-N 3.48Å; T147-L165 VanDerWaalsContact O-N 3.14Å; T147-Y169 HydrophobicContact CG2-CD1 4.43Å; T147-Y169 HydrophobicContact CG2-CG 4.45Å; T147-Y170 HydrophobicContact CG2-CD2 4.25Å; T147-Y170 HydrophobicContact CG2-CE2 3.6Å
148	T	93.5	Very high	91.4	Very high	57 Å²	57	66.1 Å²	66.1	35%	0.35	36%	0.357	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-87.7	124.6	-178.6	-60.3	0	0	0	0	111	N146 H162 L163	N146-T148 WeakPolarHBondContact OD1-CB 3.49Å; N146-T148 PolarHBondContact OD1-N 3.18Å; T148-H162 HydrophobicContact CG2-CB 3.82Å; T148-L163 WeakPolarHBondContact CA-O 3.47Å
149	I	92.8	Very high	91.2	Very high	41 Å²	41	65 Å²	65	21%	0.21	35%	0.353	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-101.2	142.8	174.4	62.1	159.7	0	0	0	111.4	H162 L163 L165 Y169	I149-H162 WeakPolarHBondContact O-CA 3.26Å; I149-L163 HydrophobicContact CG1-CB 4.09Å; I149-L163 WeakPolarHBondContact CG1-O 3.3Å; I149-L163 PolarHBondContact N-O 3.47Å; I149-L163 PolarHBondContact O-N 2.88Å; I149-L165 HydrophobicContact CD1-CD1 3.79Å; I149-L165 HydrophobicContact CD1-CG 4.37Å; I149-L165 HydrophobicContact CG1-CD1 3.96Å; I149-L165 HydrophobicContact CG1-CG 4.23Å; I149-L165 HydrophobicContact CG2-CD1 3.96Å; I149-Y169 HydrophobicContact CG2-CD2 3.88Å; I149-Y169 HydrophobicContact CG2-CE2 3.64Å
150	V	90.6	Very high	91.1	Very high	57 Å²	57	66.2 Å²	66.2	35%	0.345	37%	0.368	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-78.5	123.5	165.2	-173.4	0	0	0	0	109	K273 Y406	V150-K273 PolarHBondContact O-NZ 2.91Å; V150-K273 VanDerWaalsContact O-NZ 3.14Å; V150-Y406 HydrophobicContact CB-CD1 4.41Å; V150-Y406 HydrophobicContact CB-CE1 4.16Å; V150-Y406 HydrophobicContact CG1-CD1 3.72Å; V150-Y406 HydrophobicContact CG1-CE1 3.86Å
151	V	90.8	Very high	91	Very high	3 Å²	3	69.8 Å²	69.8	2%	0.018	39%	0.386	C	S	.	.	P	Polyproline II helix	trans	-82.1	130.2	-178.9	179.7	0	0	0	0	110	F155 R156 L159 G160 L161 L163	V151-F155 HydrophobicContact CG1-CB 3.6Å; V151-R156 HydrophobicContact CB-CG 4.31Å; V151-R156 HydrophobicContact CG1-CG 4.15Å; V151-R156 PolarHBondContact O-NE 3.45Å; V151-R156 VanDerWaalsContact O-NE 3.08Å; V151-L159 HydrophobicContact CG1-CB 4.13Å; V151-L159 HydrophobicContact CG1-CD1 4.48Å; V151-L159 HydrophobicContact CG2-CB 4.21Å; V151-G160 VanDerWaalsContact CB-O 3.3Å; V151-G160 WeakPolarHBondContact CB-O 3.49Å; V151-L161 PolarHBondContact N-O 3.32Å; V151-L163 HydrophobicContact CG2-CB 3.81Å
152	P	88.4	Confident	90.9	Very high	32 Å²	32	69 Å²	69	21%	0.208	38%	0.384	C	S	.	.	P	Polyproline II helix	trans	-61.2	145	175.5	-15.5	25.6	0	0	0	112.3	P154 F155 R156 F405 Y406	P152-P154 VanDerWaalsContact C-N 3.33Å; P152-P154 VanDerWaalsContact O-N 3.08Å; P152-F155 HydrophobicContact CB-CD2 4.11Å; P152-F155 HydrophobicContact CG-CD2 4.09Å; P152-F155 PolarHBondContact O-N 3.32Å; P152-R156 PolarHBondContact O-N 3.13Å; P152-F405 CarbonylContact C-O 3.43Å; P152-F405 WeakPolarHBondContact CA-O 3.16Å; P152-Y406 HydrophobicContact CG-CE1 4.43Å
153	K	88.9	Confident	91	Very high	72 Å²	72	67 Å²	67	31%	0.313	37%	0.37	S	S	.	.	G	3₁₀ helix	trans	-39.9	-47.9	-177.8	-77.3	176.6	-176.3	-179.3	0	115.2	F155 R156 R403 L404 F405 Y406 D407	K153-F155 PolarHBondContact O-N 3.47Å; K153-F155 VanDerWaalsContact O-N 3.16Å; K153-R156 PolarHBondContact O-N 3.35Å; K153-R403 PolarHBondContact NZ-O 3.04Å; K153-L404 WeakPolarHBondContact CD-O 3.38Å; K153-F405 WeakPolarHBondContact CG-O 3.37Å; K153-F405 PolarHBondContact N-O 2.94Å; K153-Y406 WeakPolarHBondContact CE-O 3.27Å; K153-Y406 PolarHBondContact NZ-O 3.44Å; K153-D407 WeakPolarHBondContact CE-OD1 3.37Å; K153-D407 IonicContact NZ-OD1 3.92Å; K153-D407 PolarHBondContact NZ-OD1 3.21Å
154	P	89.1	Confident	91.3	Very high	84 Å²	84	69.4 Å²	69.4	55%	0.545	38%	0.382	S	S	.	.	G	3₁₀ helix	trans	-60.5	-26	-179.3	-25.6	35.9	0	0	0	115.1	P152	P152-P154 VanDerWaalsContact C-N 3.33Å; P152-P154 VanDerWaalsContact O-N 3.08Å
155	F	89.9	Confident	91.7	Very high	115 Å²	115	67.9 Å²	67.9	50%	0.504	38%	0.378	S	S	.	.	G	3₁₀ helix	trans	-100.8	-9.9	-175.5	-58.6	-72.4	0	0	0	113.5	V151 P152 K153 I158 L159	V151-F155 HydrophobicContact CG1-CB 3.6Å; P152-F155 HydrophobicContact CB-CD2 4.11Å; P152-F155 HydrophobicContact CG-CD2 4.09Å; P152-F155 PolarHBondContact O-N 3.32Å; K153-F155 PolarHBondContact O-N 3.47Å; K153-F155 VanDerWaalsContact O-N 3.16Å; F155-I158 PolarHBondContact O-N 2.87Å; F155-I158 VanDerWaalsContact O-N 3.1Å; F155-L159 HydrophobicContact CB-CD1 4.33Å; F155-L159 PolarHBondContact O-N 3.23Å
156	R	91.6	Very high	92.2	Very high	50 Å²	50	67.2 Å²	67.2	19%	0.189	37%	0.371	C	S	.	.	H	α-helix	trans	-59.2	-34	-179.3	-63.8	-178.4	-173.5	177.9	-7.4	114.9	V151 P152 K153 I158 G160 D407	V151-R156 HydrophobicContact CB-CG 4.31Å; V151-R156 HydrophobicContact CG1-CG 4.15Å; V151-R156 PolarHBondContact O-NE 3.45Å; V151-R156 VanDerWaalsContact O-NE 3.08Å; P152-R156 PolarHBondContact O-N 3.13Å; K153-R156 PolarHBondContact O-N 3.35Å; R156-I158 PolarHBondContact O-N 2.93Å; R156-I158 VanDerWaalsContact O-N 3.17Å; R156-G160 WeakPolarHBondContact CA-O 3.45Å; R156-G160 WeakPolarHBondContact O-CA 3.2Å; R156-G160 PolarHBondContact O-N 2.9Å; R156-D407 IonicContact CZ-OD2 3.2Å; R156-D407 IonicContact NH1-OD1 3.8Å; R156-D407 IonicContact NH1-OD2 2.64Å; R156-D407 PolarHBondContact NH1-OD2 3.2Å; R156-D407 IonicContact NH2-OD2 2.86Å; R156-D407 PolarHBondContact NH2-OD2 2.98Å
157	P	92.6	Very high	92.5	Very high	117 Å²	117	68.9 Å²	68.9	76%	0.76	38%	0.379	S	S	*	.	H	α-helix	trans	-60.3	-24.7	175.9	-25.3	35.4	0	0	0	113.8
158	I	94.5	Very high	92.7	Very high	142 Å²	142	73.1 Å²	73.1	73%	0.728	40%	0.4	S	S	*	.	H	α-helix	trans	-100.8	-39.8	-176.2	-56.5	170.9	0	0	0	111	F155 R156	F155-I158 PolarHBondContact O-N 2.87Å; F155-I158 VanDerWaalsContact O-N 3.1Å; R156-I158 PolarHBondContact O-N 2.93Å; R156-I158 VanDerWaalsContact O-N 3.17Å
159	L	91.8	Very high	92.8	Very high	83 Å²	83	71.4 Å²	71.4	44%	0.435	39%	0.387	S	S	.	.	H	α-helix	trans	-112.8	-2.4	-167.9	-60.4	176	0	0	0	114.2	V151 F155 L163	V151-L159 HydrophobicContact CG1-CB 4.13Å; V151-L159 HydrophobicContact CG1-CD1 4.48Å; V151-L159 HydrophobicContact CG2-CB 4.21Å; F155-L159 HydrophobicContact CB-CD1 4.33Å; F155-L159 PolarHBondContact O-N 3.23Å; L159-L163 HydrophobicContact CD1-CD2 4.48Å
160	G	92.2	Very high	93	Very high	35 Å²	35	70.9 Å²	70.9	36%	0.361	38%	0.383	S	S	.	.			trans	76.6	-175.2	-173.2	0	0	0	0	0	113.4	V151 R156	V151-G160 VanDerWaalsContact CB-O 3.3Å; V151-G160 WeakPolarHBondContact CB-O 3.49Å; R156-G160 WeakPolarHBondContact CA-O 3.45Å; R156-G160 WeakPolarHBondContact O-CA 3.2Å; R156-G160 PolarHBondContact O-N 2.9Å
161	L	91.7	Very high	93.3	Very high	76 Å²	76	71.7 Å²	71.7	40%	0.398	39%	0.388	S	S	.	.	S	Bend	trans	-76.9	-42.3	179.4	179.5	63	0	0	0	112.2	V151	V151-L161 PolarHBondContact N-O 3.32Å
162	H	93.8	Very high	93.6	Very high	115 Å²	115	74.9 Å²	74.9	53%	0.532	40%	0.4	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.5	133.3	-178.8	-61.8	-73.1	0	0	0	108.8	T148 I149	T148-H162 HydrophobicContact CG2-CB 3.82Å; I149-H162 WeakPolarHBondContact O-CA 3.26Å
163	L	94.3	Very high	94	Very high	52 Å²	52	73.3 Å²	73.3	27%	0.272	39%	0.39	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-125.1	116.9	176	179.8	66	0	0	0	108.7	T148 I149 V151 L159 L165	T148-L163 WeakPolarHBondContact CA-O 3.47Å; I149-L163 HydrophobicContact CG1-CB 4.09Å; I149-L163 WeakPolarHBondContact CG1-O 3.3Å; I149-L163 PolarHBondContact N-O 3.47Å; I149-L163 PolarHBondContact O-N 2.88Å; V151-L163 HydrophobicContact CG2-CB 3.81Å; L159-L163 HydrophobicContact CD1-CD2 4.48Å; L163-L165 HydrophobicContact CD2-CD2 3.82Å; L163-L165 HydrophobicContact CG-CD2 4.13Å
164	D	95.5	Very high	94.4	Very high	101 Å²	101	70.1 Å²	70.1	54%	0.54	38%	0.377	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-80.3	117.8	169.8	-178.7	25.6	0	0	0	109.8	T147 G166	T147-D164 WeakPolarHBondContact CB-OD1 3.46Å; T147-D164 PolarHBondContact OG1-OD1 2.92Å; D164-G166 PolarHBondContact OD1-N 3.19Å
165	L	95.3	Very high	94.8	Very high	47 Å²	47	71.1 Å²	71.1	25%	0.246	38%	0.377	C	S	.	.			trans	-92	-15	179.9	-71.2	176.6	0	0	0	112.5	T147 I149 L163 I167 L168 Y169	T147-L165 PolarHBondContact O-N 3.48Å; T147-L165 VanDerWaalsContact O-N 3.14Å; I149-L165 HydrophobicContact CD1-CD1 3.79Å; I149-L165 HydrophobicContact CD1-CG 4.37Å; I149-L165 HydrophobicContact CG1-CD1 3.96Å; I149-L165 HydrophobicContact CG1-CG 4.23Å; I149-L165 HydrophobicContact CG2-CD1 3.96Å; L163-L165 HydrophobicContact CD2-CD2 3.82Å; L163-L165 HydrophobicContact CG-CD2 4.13Å; L165-I167 PolarHBondContact O-N 3.38Å; L165-L168 HydrophobicContact CB-CB 4.25Å; L165-L168 WeakPolarHBondContact O-CB 3.46Å; L165-L168 PolarHBondContact O-N 2.95Å; L165-Y169 HydrophobicContact CD1-CD2 4.18Å
166	G	95.5	Very high	95.2	Very high	22 Å²	22	65.9 Å²	65.9	23%	0.227	36%	0.355	C	S	.	.	T	Hydrogen-bonded Turn	trans	46.5	-122.3	-175.4	0	0	0	0	0	112.6	D164 L168 Y169	D164-G166 PolarHBondContact OD1-N 3.19Å; G166-L168 PolarHBondContact O-N 3.26Å; G166-Y169 VanDerWaalsContact O-CB 3.29Å; G166-Y169 WeakPolarHBondContact O-CB 3.42Å; G166-Y169 PolarHBondContact O-N 3.23Å
167	I	96.2	Very high	95.4	Very high	125 Å²	125	63.5 Å²	63.5	64%	0.641	35%	0.346	S	S	*	.	H	α-helix	trans	-59.3	-30.2	179.2	-170.1	59.9	0	0	0	113.7	L165 Y169 Y170 V171	L165-I167 PolarHBondContact O-N 3.38Å; I167-Y169 PolarHBondContact O-N 3.12Å; I167-Y170 WeakPolarHBondContact O-CB 3.27Å; I167-Y170 PolarHBondContact O-N 2.89Å; I167-V171 PolarHBondContact O-N 2.92Å
168	L	97.1	Very high	95.7	Very high	109 Å²	109	58.6 Å²	58.6	57%	0.571	31%	0.313	S	S	*	.	H	α-helix	trans	-66.2	-24.7	178.6	-62.5	177.1	0	0	0	111.8	L165 G166 V171 Y172	L165-L168 HydrophobicContact CB-CB 4.25Å; L165-L168 WeakPolarHBondContact O-CB 3.46Å; L165-L168 PolarHBondContact O-N 2.95Å; G166-L168 PolarHBondContact O-N 3.26Å; L168-V171 PolarHBondContact O-N 3.31Å; L168-Y172 WeakPolarHBondContact O-CB 3.16Å; L168-Y172 PolarHBondContact O-N 2.94Å
169	Y	96.1	Very high	95.9	Very high	22 Å²	22	53.7 Å²	53.7	9%	0.086	29%	0.287	C	S	.	.	H	α-helix	trans	-66.7	-39.9	172.1	-164.6	-96	0	0	0	111.6	Y140 T147 I149 L165 G166 I167 Y172 M173	Y140-Y169 HydrophobicContact CD1-CE1 4.5Å; Y140-Y169 HydrophobicContact CE1-CD1 4.03Å; Y140-Y169 AromaticContact CE1-CE1 3.66Å; Y140-Y169 HydrophobicContact CE1-CE1 3.66Å; Y140-Y169 HydrophobicContact CE2-CE1 4.24Å; Y140-Y169 AromaticContact CZ-CE1 3.5Å; Y140-Y169 VanDerWaalsContact CZ-CE1 3.5Å; Y140-Y169 WeakPolarHBondContact OH-CE1 3.38Å; Y140-Y169 PolarHBondContact OH-OH 3.39Å; T147-Y169 HydrophobicContact CG2-CD1 4.43Å; T147-Y169 HydrophobicContact CG2-CG 4.45Å; I149-Y169 HydrophobicContact CG2-CD2 3.88Å; I149-Y169 HydrophobicContact CG2-CE2 3.64Å; L165-Y169 HydrophobicContact CD1-CD2 4.18Å; G166-Y169 VanDerWaalsContact O-CB 3.29Å; G166-Y169 WeakPolarHBondContact O-CB 3.42Å; G166-Y169 PolarHBondContact O-N 3.23Å; I167-Y169 PolarHBondContact O-N 3.12Å; Y169-Y172 HydrophobicContact CE2-CD1 4.44Å; Y169-Y172 WeakPolarHBondContact O-CB 3.33Å; Y169-Y172 PolarHBondContact O-N 2.75Å; Y169-M173 HydrophobicContact CD1-CE 3.83Å; Y169-M173 HydrophobicContact CD1-CG 4.24Å; Y169-M173 HydrophobicContact CD1-SD 4.07Å; Y169-M173 HydrophobicContact CE1-CE 4.09Å; Y169-M173 HydrophobicContact CE1-CG 4.03Å; Y169-M173 HydrophobicContact CE1-SD 3.73Å; Y169-M173 WeakPolarHBondContact O-CG 3.23Å; Y169-M173 PolarHBondContact O-N 3.49Å
170	Y	96.7	Very high	96.2	Very high	30 Å²	30	49.7 Å²	49.7	12%	0.118	27%	0.266	C	S	.	.	H	α-helix	trans	-68.1	-39.1	174.9	-70.2	-92.4	0	0	0	112.1	L137 Y140 F141 T147 I167 Y172 M173 G174	L137-Y170 HydrophobicContact CB-CD1 4.18Å; L137-Y170 HydrophobicContact CD2-CD1 4.34Å; L137-Y170 HydrophobicContact CG-CD1 4.05Å; Y140-Y170 HydrophobicContact CD1-CE1 4.27Å; F141-Y170 VanDerWaalsContact CA-OH 3.29Å; F141-Y170 WeakPolarHBondContact CA-OH 3.43Å; F141-Y170 HydrophobicContact CB-CE1 3.91Å; F141-Y170 WeakPolarHBondContact CD2-OH 3.29Å; T147-Y170 HydrophobicContact CG2-CD2 4.25Å; T147-Y170 HydrophobicContact CG2-CE2 3.6Å; I167-Y170 WeakPolarHBondContact O-CB 3.27Å; I167-Y170 PolarHBondContact O-N 2.89Å; Y170-Y172 VanDerWaalsContact C-N 3.31Å; Y170-Y172 PolarHBondContact O-N 3.49Å; Y170-M173 HydrophobicContact CD1-CE 3.36Å; Y170-M173 HydrophobicContact CD2-CE 4.46Å; Y170-M173 HydrophobicContact CE1-CE 3.65Å; Y170-M173 HydrophobicContact CG-CE 3.8Å; Y170-M173 PolarHBondContact O-N 3.09Å; Y170-G174 PolarHBondContact O-N 3.42Å
171	V	97.4	Very high	96.5	Very high	74 Å²	74	48 Å²	48	45%	0.448	25%	0.249	S	C	.	.	H	α-helix	trans	-59.9	-44.4	171.6	176.5	0	0	0	0	110.4	I167 L168 M173 G174 L175	I167-V171 PolarHBondContact O-N 2.92Å; L168-V171 PolarHBondContact O-N 3.31Å; V171-M173 PolarHBondContact O-N 3.09Å; V171-G174 PolarHBondContact O-N 3.37Å; V171-L175 HydrophobicContact CG1-CD1 3.91Å; V171-L175 HydrophobicContact CG1-CG 4.28Å; V171-L175 WeakPolarHBondContact O-CB 3.36Å; V171-L175 WeakPolarHBondContact O-CG 3.44Å; V171-L175 PolarHBondContact O-N 3.14Å
172	Y	97.2	Very high	96.7	Very high	69 Å²	69	45.5 Å²	45.5	27%	0.271	24%	0.236	S	C	.	.	H	α-helix	trans	-57.5	-47	174.4	161.1	-98.6	0	0	0	112.2	L168 Y169 Y170 G174 L175 L176 S272 L276	L168-Y172 WeakPolarHBondContact O-CB 3.16Å; L168-Y172 PolarHBondContact O-N 2.94Å; Y169-Y172 HydrophobicContact CE2-CD1 4.44Å; Y169-Y172 WeakPolarHBondContact O-CB 3.33Å; Y169-Y172 PolarHBondContact O-N 2.75Å; Y170-Y172 VanDerWaalsContact C-N 3.31Å; Y170-Y172 PolarHBondContact O-N 3.49Å; Y172-G174 PolarHBondContact O-N 2.95Å; Y172-L175 PolarHBondContact O-N 3.41Å; Y172-L176 HydrophobicContact CE1-CD2 4.4Å; Y172-L176 WeakPolarHBondContact O-CB 3.4Å; Y172-L176 PolarHBondContact O-N 2.95Å; Y172-S272 WeakPolarHBondContact OH-CB 3.34Å; Y172-S272 PolarHBondContact OH-OG 3.12Å; Y172-S272 VanDerWaalsContact OH-OG 3.14Å; Y172-L276 HydrophobicContact CE2-CD1 4.48Å
173	M	96.8	Very high	97	Very high	0 Å²	0	40 Å²	40	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-61	-43.7	178.4	-71.3	-171.1	-67.7	0	0	112.4	L137 Y140 Y169 Y170 V171 L176 A177 I267	L137-M173 HydrophobicContact CD1-CB 3.89Å; L137-M173 HydrophobicContact CG-CB 4.4Å; L137-M173 HydrophobicContact CG-CE 4.29Å; Y140-M173 HydrophobicContact CD1-CE 3.65Å; Y140-M173 HydrophobicContact CD1-SD 3.97Å; Y140-M173 HydrophobicContact CD2-SD 3.81Å; Y140-M173 HydrophobicContact CE1-CE 4.23Å; Y140-M173 HydrophobicContact CE1-SD 4.33Å; Y140-M173 HydrophobicContact CE2-SD 4.17Å; Y140-M173 HydrophobicContact CG-CE 3.82Å; Y140-M173 HydrophobicContact CG-SD 3.68Å; Y169-M173 HydrophobicContact CD1-CE 3.83Å; Y169-M173 HydrophobicContact CD1-CG 4.24Å; Y169-M173 HydrophobicContact CD1-SD 4.07Å; Y169-M173 HydrophobicContact CE1-CE 4.09Å; Y169-M173 HydrophobicContact CE1-CG 4.03Å; Y169-M173 HydrophobicContact CE1-SD 3.73Å; Y169-M173 WeakPolarHBondContact O-CG 3.23Å; Y169-M173 PolarHBondContact O-N 3.49Å; Y170-M173 HydrophobicContact CD1-CE 3.36Å; Y170-M173 HydrophobicContact CD2-CE 4.46Å; Y170-M173 HydrophobicContact CE1-CE 3.65Å; Y170-M173 HydrophobicContact CG-CE 3.8Å; Y170-M173 PolarHBondContact O-N 3.09Å; V171-M173 PolarHBondContact O-N 3.09Å; M173-L176 WeakPolarHBondContact O-CB 3.29Å; M173-L176 PolarHBondContact O-N 3.21Å; M173-A177 PolarHBondContact O-N 3.38Å; M173-I267 HydrophobicContact CB-CD1 3.77Å; M173-I267 HydrophobicContact CB-CG1 4.43Å; M173-I267 HydrophobicContact CG-CD1 4Å; M173-I267 HydrophobicContact CG-CG1 4.1Å; M173-I267 HydrophobicContact CG-CG2 4.15Å; M173-I267 HydrophobicContact SD-CG1 4.5Å; M173-I267 HydrophobicContact SD-CG2 3.44Å; M173-I267 WeakPolarHBondContact SD-CG2 3.46Å
174	G	97.4	Very high	97.2	Very high	5 Å²	5	37.5 Å²	37.5	5%	0.052	20%	0.197	C	C	.	.	H	α-helix	trans	-63.1	-46	175.8	0	0	0	0	0	112.2	Y170 V171 Y172 L176 A177 V178	Y170-G174 PolarHBondContact O-N 3.42Å; V171-G174 PolarHBondContact O-N 3.37Å; Y172-G174 PolarHBondContact O-N 2.95Å; G174-L176 VanDerWaalsContact C-N 3.29Å; G174-L176 PolarHBondContact O-N 2.95Å; G174-A177 PolarHBondContact O-N 3.43Å; G174-V178 WeakPolarHBondContact O-CG2 3.43Å; G174-V178 PolarHBondContact O-N 3.12Å; G174-V178 VanDerWaalsContact O-N 3.15Å
175	L	97.9	Very high	97.3	Very high	104 Å²	104	34.3 Å²	34.3	55%	0.545	18%	0.18	S	C	.	.	H	α-helix	trans	-67.3	-28.2	176.8	-69.2	179.7	0	0	0	112.9	V171 Y172 V178 F179	V171-L175 HydrophobicContact CG1-CD1 3.91Å; V171-L175 HydrophobicContact CG1-CG 4.28Å; V171-L175 WeakPolarHBondContact O-CB 3.36Å; V171-L175 WeakPolarHBondContact O-CG 3.44Å; V171-L175 PolarHBondContact O-N 3.14Å; Y172-L175 PolarHBondContact O-N 3.41Å; L175-V178 PolarHBondContact O-N 2.86Å; L175-F179 VanDerWaalsContact O-CB 3.23Å; L175-F179 WeakPolarHBondContact O-CB 3.47Å; L175-F179 PolarHBondContact O-N 3.43Å
176	L	98	Very high	97.4	Very high	6 Å²	6	34 Å²	34	3%	0.031	18%	0.178	C	C	.	.	H	α-helix	trans	-64.4	-42.7	174.2	-178.2	62.2	0	0	0	110.8	Y172 M173 G174 F179 C180 I267 M275 L276	Y172-L176 HydrophobicContact CE1-CD2 4.4Å; Y172-L176 WeakPolarHBondContact O-CB 3.4Å; Y172-L176 PolarHBondContact O-N 2.95Å; M173-L176 WeakPolarHBondContact O-CB 3.29Å; M173-L176 PolarHBondContact O-N 3.21Å; G174-L176 VanDerWaalsContact C-N 3.29Å; G174-L176 PolarHBondContact O-N 2.95Å; L176-F179 PolarHBondContact O-N 3.37Å; L176-C180 WeakPolarHBondContact O-CB 3.31Å; L176-C180 PolarHBondContact O-N 3.01Å; L176-C180 PolarHBondContact O-SG 3.49Å; L176-I267 HydrophobicContact CD2-CD1 4Å; L176-I267 HydrophobicContact CD2-CG1 3.83Å; L176-M275 HydrophobicContact CD1-CE 3.8Å; L176-M275 HydrophobicContact CD2-CE 4Å; L176-M275 HydrophobicContact CG-CE 4.1Å; L176-L276 HydrophobicContact CD1-CD1 4.04Å; L176-L276 HydrophobicContact CD1-CD2 3.65Å; L176-L276 HydrophobicContact CD1-CG 3.9Å
177	A	96.3	Very high	97.6	Very high	0 Å²	0	33 Å²	33	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-62.9	-46.5	174.3	0	0	0	0	0	111.5	M173 G174 F179 C180 T181 M260 A263	M173-A177 PolarHBondContact O-N 3.38Å; G174-A177 PolarHBondContact O-N 3.43Å; A177-F179 VanDerWaalsContact C-N 3.31Å; A177-F179 PolarHBondContact O-N 3.44Å; A177-C180 PolarHBondContact O-N 3.42Å; A177-T181 WeakPolarHBondContact O-CG2 3.44Å; A177-T181 PolarHBondContact O-N 3.24Å; A177-T181 PolarHBondContact O-OG1 3.49Å; A177-M260 HydrophobicContact CB-CE 3.86Å; A177-M260 HydrophobicContact CB-SD 4.22Å; A177-A263 HydrophobicContact CB-CB 4.05Å
178	V	98.2	Very high	97.7	Very high	13 Å²	13	28 Å²	28	8%	0.079	15%	0.145	C	C	.	.	H	α-helix	trans	-58.3	-43.9	175.3	178	0	0	0	0	111.3	L126 P129 T130 G174 L175 T181 N182	L126-V178 HydrophobicContact CD2-CG1 3.71Å; P129-V178 HydrophobicContact CB-CB 4.35Å; P129-V178 HydrophobicContact CB-CG2 3.87Å; T130-V178 VanDerWaalsContact OG1-CG2 3.26Å; T130-V178 WeakPolarHBondContact OG1-CG2 3.31Å; G174-V178 WeakPolarHBondContact O-CG2 3.43Å; G174-V178 PolarHBondContact O-N 3.12Å; G174-V178 VanDerWaalsContact O-N 3.15Å; L175-V178 PolarHBondContact O-N 2.86Å; V178-T181 PolarHBondContact O-OG1 2.82Å; V178-T181 VanDerWaalsContact O-OG1 3.12Å; V178-N182 WeakPolarHBondContact O-CB 3.35Å; V178-N182 PolarHBondContact O-N 3.31Å; V178-N182 PolarHBondContact O-ND2 2.94Å
179	F	98.6	Very high	97.6	Very high	39 Å²	39	24.1 Å²	24.1	17%	0.171	13%	0.131	C	C	.	.	H	α-helix	trans	-64.5	-52.1	179.8	172.5	-99.5	0	0	0	111	L175 L176 A177 T181 N182 A183 L276 F279 V283 F286	L175-F179 VanDerWaalsContact O-CB 3.23Å; L175-F179 WeakPolarHBondContact O-CB 3.47Å; L175-F179 PolarHBondContact O-N 3.43Å; L176-F179 PolarHBondContact O-N 3.37Å; A177-F179 VanDerWaalsContact C-N 3.31Å; A177-F179 PolarHBondContact O-N 3.44Å; F179-T181 VanDerWaalsContact C-N 3.32Å; F179-T181 PolarHBondContact O-N 3.21Å; F179-N182 PolarHBondContact O-N 3.21Å; F179-A183 HydrophobicContact CD1-CB 4.49Å; F179-A183 HydrophobicContact CD2-CB 4.24Å; F179-A183 HydrophobicContact CE1-CB 4.13Å; F179-A183 HydrophobicContact CE2-CB 3.85Å; F179-A183 HydrophobicContact CZ-CB 3.77Å; F179-A183 WeakPolarHBondContact O-CB 3.48Å; F179-A183 PolarHBondContact O-N 3.19Å; F179-L276 HydrophobicContact CD1-CD2 3.98Å; F179-L276 HydrophobicContact CE1-CD2 3.8Å; F179-F279 HydrophobicContact CE1-CD1 4.18Å; F179-V283 HydrophobicContact CE1-CG2 4Å; F179-V283 HydrophobicContact CZ-CB 4.33Å; F179-V283 HydrophobicContact CZ-CG2 3.53Å; F179-F286 HydrophobicContact CD2-CG 4.47Å; F179-F286 HydrophobicContact CE2-CB 4.08Å; F179-F286 HydrophobicContact CE2-CD1 4.05Å; F179-F286 HydrophobicContact CE2-CD2 4.35Å; F179-F286 AromaticContact CE2-CG 3.9Å; F179-F286 HydrophobicContact CE2-CG 3.9Å
180	C	98.4	Very high	97.7	Very high	0 Å²	0	23.3 Å²	23.3	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-60.4	-41	-174.3	-65.6	0	0	0	0	112.1	L176 A177 I184 G259 F279	L176-C180 WeakPolarHBondContact O-CB 3.31Å; L176-C180 PolarHBondContact O-N 3.01Å; L176-C180 PolarHBondContact O-SG 3.49Å; A177-C180 PolarHBondContact O-N 3.42Å; C180-I184 WeakPolarHBondContact O-CG1 3.26Å; C180-I184 PolarHBondContact O-N 3.21Å; C180-G259 VanDerWaalsContact CB-O 3.24Å; C180-G259 WeakPolarHBondContact CB-O 3.42Å; C180-F279 HydrophobicContact CB-CE1 4.02Å; C180-F279 HydrophobicContact CB-CZ 4.15Å
181	T	97.3	Very high	97.8	Very high	0 Å²	0	22.1 Å²	22.1	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-67.7	-48.3	179	57.9	0	0	0	0	112	M108 A177 V178 F179 N185 Y256	M108-T181 HydrophobicContact CE-CG2 3.84Å; M108-T181 HydrophobicContact SD-CG2 4.24Å; A177-T181 WeakPolarHBondContact O-CG2 3.44Å; A177-T181 PolarHBondContact O-N 3.24Å; A177-T181 PolarHBondContact O-OG1 3.49Å; V178-T181 PolarHBondContact O-OG1 2.82Å; V178-T181 VanDerWaalsContact O-OG1 3.12Å; F179-T181 VanDerWaalsContact C-N 3.32Å; F179-T181 PolarHBondContact O-N 3.21Å; T181-N185 WeakPolarHBondContact O-CB 3.49Å; T181-N185 PolarHBondContact O-N 2.97Å; T181-Y256 WeakPolarHBondContact CG2-O 3.43Å
182	N	97.9	Very high	97.9	Very high	22 Å²	22	18.6 Å²	18.6	12%	0.118	10%	0.103	C	C	.	.	H	α-helix	trans	-72.9	-34.2	-177.3	-74.8	-76.7	0	0	0	112.2	K125 V178 F179 N185 I186	K125-N182 PolarHBondContact O-ND2 3.49Å; V178-N182 WeakPolarHBondContact O-CB 3.35Å; V178-N182 PolarHBondContact O-N 3.31Å; V178-N182 PolarHBondContact O-ND2 2.94Å; F179-N182 PolarHBondContact O-N 3.21Å; N182-N185 WeakPolarHBondContact O-CB 3.31Å; N182-N185 PolarHBondContact O-N 2.85Å; N182-N185 VanDerWaalsContact O-N 3.14Å; N182-I186 WeakPolarHBondContact O-CG1 3.14Å; N182-I186 WeakPolarHBondContact O-CG2 3.36Å; N182-I186 PolarHBondContact O-N 3.1Å
183	A	98.5	Very high	98	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-67.5	-38.4	-176.7	0	0	0	0	0	112.3	F179 L187 Q282	F179-A183 HydrophobicContact CD1-CB 4.49Å; F179-A183 HydrophobicContact CD2-CB 4.24Å; F179-A183 HydrophobicContact CE1-CB 4.13Å; F179-A183 HydrophobicContact CE2-CB 3.85Å; F179-A183 HydrophobicContact CZ-CB 3.77Å; F179-A183 WeakPolarHBondContact O-CB 3.48Å; F179-A183 PolarHBondContact O-N 3.19Å; A183-L187 PolarHBondContact O-N 3.29Å; A183-Q282 HydrophobicContact CB-CB 3.97Å
184	I	98.6	Very high	98.1	Very high	0 Å²	0	16.4 Å²	16.4	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-65.7	-45	169.3	-62.5	168.1	0	0	0	109.3	C180 I186 L187 C255 A258 F262 F279	C180-I184 WeakPolarHBondContact O-CG1 3.26Å; C180-I184 PolarHBondContact O-N 3.21Å; I184-I186 VanDerWaalsContact C-N 3.33Å; I184-I186 PolarHBondContact O-N 2.88Å; I184-L187 CarbonylContact O-C 3.54Å; I184-L187 PolarHBondContact O-N 2.95Å; I184-L187 VanDerWaalsContact O-N 3.11Å; I184-C255 HydrophobicContact CG2-CB 4.36Å; I184-A258 HydrophobicContact CD1-CB 3.9Å; I184-F262 HydrophobicContact CD1-CD2 4.04Å; I184-F262 HydrophobicContact CD1-CE2 4Å; I184-F279 HydrophobicContact CD1-CE1 4.18Å; I184-F279 HydrophobicContact CD1-CZ 4.26Å; I184-F279 HydrophobicContact CG1-CE1 4.13Å
185	N	98	Very high	98.1	Very high	33 Å²	33	16.2 Å²	16.2	18%	0.176	9%	0.093	C	C	.	.	H	α-helix	trans	-62.9	-33.8	-176.3	-161.2	26.3	0	0	0	114.5	T181 N182 A188 D252 C255	T181-N185 WeakPolarHBondContact O-CB 3.49Å; T181-N185 PolarHBondContact O-N 2.97Å; N182-N185 WeakPolarHBondContact O-CB 3.31Å; N182-N185 PolarHBondContact O-N 2.85Å; N182-N185 VanDerWaalsContact O-N 3.14Å; N185-A188 WeakPolarHBondContact O-CB 3.28Å; N185-D252 VanDerWaalsContact CG-OD1 3.26Å; N185-D252 PolarHBondContact ND2-OD1 2.95Å; N185-D252 PolarHBondContact OD1-OD1 3.48Å; N185-C255 HydrophobicContact CB-CB 3.77Å
186	I	98.3	Very high	98.2	Very high	40 Å²	40	11.3 Å²	11.3	21%	0.205	7%	0.068	C	C	.	.	H	α-helix	trans	-86.5	-11	177.4	66.5	168.8	0	0	0	113.5	N182 I184 N285 F286 L293	N182-I186 WeakPolarHBondContact O-CG1 3.14Å; N182-I186 WeakPolarHBondContact O-CG2 3.36Å; N182-I186 PolarHBondContact O-N 3.1Å; I184-I186 VanDerWaalsContact C-N 3.33Å; I184-I186 PolarHBondContact O-N 2.88Å; I186-N285 PolarHBondContact O-ND2 3.46Å; I186-F286 HydrophobicContact CD1-CB 4.06Å; I186-F286 HydrophobicContact CD1-CD2 3.75Å; I186-F286 HydrophobicContact CD1-CG 4.38Å; I186-L293 HydrophobicContact CD1-CD1 3.95Å
187	L	98.7	Very high	98.2	Very high	3 Å²	3	11.2 Å²	11.2	2%	0.016	7%	0.067	C	C	.	.	S	Bend	trans	-102.7	65.4	172.2	-174.6	53.2	0	0	0	109	A183 I184 L193 Q197 P281 Q282 N285 L363 I364	A183-L187 PolarHBondContact O-N 3.29Å; I184-L187 CarbonylContact O-C 3.54Å; I184-L187 PolarHBondContact O-N 2.95Å; I184-L187 VanDerWaalsContact O-N 3.11Å; L187-L193 HydrophobicContact CD1-CD2 4.38Å; L187-L193 HydrophobicContact CG-CD2 4.41Å; L187-L193 WeakPolarHBondContact O-CD2 3.42Å; L187-Q197 PolarHBondContact O-NE2 3.06Å; L187-P281 HydrophobicContact CD2-CB 4.39Å; L187-Q282 HydrophobicContact CD2-CG 4.23Å; L187-N285 HydrophobicContact CB-CB 4.48Å; L187-N285 HydrophobicContact CD1-CB 4.16Å; L187-N285 HydrophobicContact CD2-CB 4.28Å; L187-L363 HydrophobicContact CD1-CB 4.12Å; L187-L363 HydrophobicContact CD1-CD2 4.42Å; L187-L363 HydrophobicContact CD2-CD2 4.4Å; L187-I364 HydrophobicContact CD1-CG1 4.11Å
188	A	98.1	Very high	98.4	Very high	20 Å²	20	11.2 Å²	11.2	17%	0.165	7%	0.067	C	C	.	.			trans	-144.5	176.5	-165.6	0	0	0	0	0	111.8	N185 E194 I364	N185-A188 WeakPolarHBondContact O-CB 3.28Å; A188-E194 WeakPolarHBondContact CA-OE1 3.33Å; A188-E194 HydrophobicContact CB-CG 3.65Å; A188-E194 VanDerWaalsContact CB-OE1 3.22Å; A188-E194 WeakPolarHBondContact CB-OE1 3.29Å; A188-I364 WeakPolarHBondContact O-CD1 3.11Å
189	G	95.7	Very high	98.4	Very high	27 Å²	27	11.9 Å²	11.9	28%	0.278	7%	0.07	S	C	.	.			trans	96.5	17.7	168.6	0	0	0	0	0	115.7	N47 E194	N47-G189 PolarHBondContact ND2-O 3.27Å; G189-E194 PolarHBondContact N-OE1 3.02Å
190	I	98.5	Very high	98.4	Very high	4 Å²	4	11 Å²	11	2%	0.021	7%	0.068	C	C	.	.	S	Bend	trans	-130.5	145.5	162.1	62.6	177	0	0	0	108.9	G192 L193 P305 L314 E376 L379 T380 L383	I190-G192 PolarHBondContact O-N 2.78Å; I190-L193 HydrophobicContact CD1-CB 4.46Å; I190-L193 HydrophobicContact CD1-CD2 4.05Å; I190-L193 HydrophobicContact CG1-CB 3.74Å; I190-L193 HydrophobicContact CG1-CD2 3.75Å; I190-L193 HydrophobicContact CG1-CG 4.31Å; I190-L193 WeakPolarHBondContact O-CB 3.46Å; I190-L193 PolarHBondContact O-N 3.21Å; I190-P305 HydrophobicContact CG2-CG 4.08Å; I190-L314 HydrophobicContact CG2-CD1 3.93Å; I190-E376 WeakPolarHBondContact CA-OE1 3.39Å; I190-E376 HydrophobicContact CB-CG 4.1Å; I190-E376 HydrophobicContact CG2-CG 4.48Å; I190-L379 HydrophobicContact CD1-CB 4.32Å; I190-L379 HydrophobicContact CD1-CD2 4.18Å; I190-L379 HydrophobicContact CD1-CG 3.95Å; I190-T380 WeakPolarHBondContact CD1-OG1 3.22Å; I190-T380 WeakPolarHBondContact CG1-OG1 3.35Å; I190-L383 HydrophobicContact CD1-CD1 3.71Å
191	N	98.8	Very high	98.4	Very high	5 Å²	5	11 Å²	11	3%	0.027	7%	0.068	C	C	.	.	T	Hydrogen-bonded Turn	trans	-55.7	121.5	-169.8	-70.1	-51.2	0	0	0	113.1	D45 K48 Y244 S246 E376 T380	D45-N191 PolarHBondContact OD2-ND2 3.39Å; D45-N191 PolarHBondContact OD2-OD1 3.27Å; K48-N191 WeakPolarHBondContact CE-ND2 3.31Å; K48-N191 PolarHBondContact NZ-ND2 3.46Å; N191-Y244 HydrophobicContact CB-CD2 4.06Å; N191-S246 WeakPolarHBondContact CB-OG 3.31Å; N191-S246 WeakPolarHBondContact OD1-CB 3.31Å; N191-S246 PolarHBondContact OD1-OG 3.45Å; N191-E376 WeakPolarHBondContact CB-OE1 3.26Å; N191-E376 PolarHBondContact N-OE1 3.29Å; N191-E376 PolarHBondContact ND2-OE1 2.79Å; N191-E376 PolarHBondContact ND2-OE2 2.81Å; N191-T380 WeakPolarHBondContact O-CG2 3.4Å; N191-T380 PolarHBondContact O-OG1 2.87Å
192	G	98.7	Very high	98.5	Very high	0 Å²	0	11 Å²	11	0%	0	7%	0.068	C	C	.	.	T	Hydrogen-bonded Turn	trans	87.1	0.3	176.4	0	0	0	0	0	116.2	I190 G196 N242	I190-G192 PolarHBondContact O-N 2.78Å; G192-G196 VanDerWaalsContact O-CA 3.28Å; G192-G196 WeakPolarHBondContact O-CA 3.44Å; G192-G196 PolarHBondContact O-N 3Å; G192-N242 WeakPolarHBondContact CA-OD1 3.4Å; G192-N242 PolarHBondContact N-O 3.28Å; G192-N242 PolarHBondContact N-OD1 3.12Å
193	L	98.9	Very high	98.6	Very high	2 Å²	2	11.6 Å²	11.6	1%	0.01	8%	0.076	C	C	.	.	H	α-helix	trans	-75.8	-42.9	-171.8	-179.1	61.8	0	0	0	113.3	L187 I190 Q197 I364 T380 L383	L187-L193 HydrophobicContact CD1-CD2 4.38Å; L187-L193 HydrophobicContact CG-CD2 4.41Å; L187-L193 WeakPolarHBondContact O-CD2 3.42Å; I190-L193 HydrophobicContact CD1-CB 4.46Å; I190-L193 HydrophobicContact CD1-CD2 4.05Å; I190-L193 HydrophobicContact CG1-CB 3.74Å; I190-L193 HydrophobicContact CG1-CD2 3.75Å; I190-L193 HydrophobicContact CG1-CG 4.31Å; I190-L193 WeakPolarHBondContact O-CB 3.46Å; I190-L193 PolarHBondContact O-N 3.21Å; L193-Q197 WeakPolarHBondContact O-CB 3.48Å; L193-Q197 VanDerWaalsContact O-CG 3.26Å; L193-Q197 WeakPolarHBondContact O-CG 3.47Å; L193-Q197 PolarHBondContact O-N 3Å; L193-Q197 PolarHBondContact O-NE2 3.5Å; L193-I364 HydrophobicContact CD2-CD1 3.81Å; L193-I364 HydrophobicContact CD2-CG1 4.31Å; L193-T380 HydrophobicContact CB-CG2 4.3Å; L193-L383 HydrophobicContact CD1-CB 3.69Å; L193-L383 HydrophobicContact CD1-CD1 3.97Å; L193-L383 HydrophobicContact CD1-CG 4.38Å; L193-L383 HydrophobicContact CD2-CD1 3.96Å
194	E	98.8	Very high	98.6	Very high	22 Å²	22	12.1 Å²	12.1	10%	0.103	8%	0.079	C	C	.	.	H	α-helix	trans	-66.5	-54.7	-176.5	-55.5	83	175.9	0	0	110.4	A188 G189 Q197 S198 V250 F254	A188-E194 WeakPolarHBondContact CA-OE1 3.33Å; A188-E194 HydrophobicContact CB-CG 3.65Å; A188-E194 VanDerWaalsContact CB-OE1 3.22Å; A188-E194 WeakPolarHBondContact CB-OE1 3.29Å; G189-E194 PolarHBondContact N-OE1 3.02Å; E194-Q197 WeakPolarHBondContact O-CG 3.37Å; E194-S198 PolarHBondContact O-N 3.07Å; E194-S198 PolarHBondContact O-OG 3.16Å; E194-V250 HydrophobicContact CB-CG2 3.78Å; E194-V250 HydrophobicContact CG-CG2 4.11Å; E194-F254 HydrophobicContact CB-CD1 4.36Å
195	A	98.9	Very high	98.6	Very high	0 Å²	0	12.1 Å²	12.1	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-66.7	-38.5	175.5	0	0	0	0	0	111.8	L199 T235 L239 V250 F254	A195-L199 WeakPolarHBondContact O-CB 3.37Å; A195-L199 PolarHBondContact O-N 2.93Å; A195-T235 HydrophobicContact CB-CG2 4.07Å; A195-T235 WeakPolarHBondContact O-CG2 3.37Å; A195-L239 HydrophobicContact CB-CB 4.2Å; A195-L239 HydrophobicContact CB-CD1 3.87Å; A195-V250 HydrophobicContact CB-CG1 4.26Å; A195-F254 HydrophobicContact CB-CE1 4.22Å; A195-F254 HydrophobicContact CB-CZ 4.22Å
196	G	98.9	Very high	98.6	Very high	2 Å²	2	11.8 Å²	11.8	2%	0.021	8%	0.077	C	C	.	.	H	α-helix	trans	-65.1	-47.1	-179.4	0	0	0	0	0	113.5	G192 S198 L199 V200	G192-G196 VanDerWaalsContact O-CA 3.28Å; G192-G196 WeakPolarHBondContact O-CA 3.44Å; G192-G196 PolarHBondContact O-N 3Å; G196-S198 VanDerWaalsContact C-N 3.33Å; G196-S198 PolarHBondContact O-N 3.35Å; G196-L199 WeakPolarHBondContact O-CB 3.44Å; G196-L199 PolarHBondContact O-N 3.14Å; G196-L199 VanDerWaalsContact O-N 3.17Å; G196-V200 PolarHBondContact O-N 3.12Å
197	Q	98.9	Very high	98.6	Very high	3 Å²	3	13.3 Å²	13.3	1%	0.014	9%	0.088	C	C	.	.	H	α-helix	trans	-65.6	-39.9	-179.9	76.1	-168.4	-86.2	0	0	110.8	L187 L193 E194 L199 V200 I201 L384	L187-Q197 PolarHBondContact O-NE2 3.06Å; L193-Q197 WeakPolarHBondContact O-CB 3.48Å; L193-Q197 VanDerWaalsContact O-CG 3.26Å; L193-Q197 WeakPolarHBondContact O-CG 3.47Å; L193-Q197 PolarHBondContact O-N 3Å; L193-Q197 PolarHBondContact O-NE2 3.5Å; E194-Q197 WeakPolarHBondContact O-CG 3.37Å; Q197-L199 VanDerWaalsContact C-N 3.3Å; Q197-L199 PolarHBondContact O-N 3.33Å; Q197-V200 PolarHBondContact O-N 3.27Å; Q197-I201 VanDerWaalsContact O-CG1 3.31Å; Q197-I201 WeakPolarHBondContact O-CG1 3.39Å; Q197-I201 PolarHBondContact O-N 2.97Å; Q197-L384 HydrophobicContact CB-CD2 4.28Å; Q197-L384 VanDerWaalsContact N-CD2 3.3Å
198	S	98.9	Very high	98.6	Very high	0 Å²	0	13.2 Å²	13.2	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-65.1	-33.6	174.3	-67.9	0	0	0	0	112.1	E194 G196 I201 S202 F262	E194-S198 PolarHBondContact O-N 3.07Å; E194-S198 PolarHBondContact O-OG 3.16Å; G196-S198 VanDerWaalsContact C-N 3.33Å; G196-S198 PolarHBondContact O-N 3.35Å; S198-I201 PolarHBondContact O-N 3.37Å; S198-S202 WeakPolarHBondContact O-CB 3.16Å; S198-S202 PolarHBondContact O-N 3.17Å; S198-S202 PolarHBondContact O-OG 3.21Å; S198-F262 WeakPolarHBondContact O-CZ 3.01Å
199	L	98.9	Very high	98.5	Very high	28 Å²	28	12.3 Å²	12.3	15%	0.147	8%	0.08	C	C	.	.	H	α-helix	trans	-63.7	-43.5	173.2	-153.8	98.7	0	0	0	111.6	A195 G196 Q197 S202 A203 F232 T235 L236 L239	A195-L199 WeakPolarHBondContact O-CB 3.37Å; A195-L199 PolarHBondContact O-N 2.93Å; G196-L199 WeakPolarHBondContact O-CB 3.44Å; G196-L199 PolarHBondContact O-N 3.14Å; G196-L199 VanDerWaalsContact O-N 3.17Å; Q197-L199 VanDerWaalsContact C-N 3.3Å; Q197-L199 PolarHBondContact O-N 3.33Å; L199-S202 WeakPolarHBondContact CA-OG 3.47Å; L199-S202 PolarHBondContact O-OG 3.44Å; L199-A203 VanDerWaalsContact O-CB 3.28Å; L199-A203 WeakPolarHBondContact O-CB 3.3Å; L199-A203 PolarHBondContact O-N 3.38Å; L199-F232 HydrophobicContact CD1-CD2 4.17Å; L199-F232 HydrophobicContact CD1-CE2 4.13Å; L199-F232 HydrophobicContact CD2-CE2 3.85Å; L199-F232 HydrophobicContact CD2-CZ 4.19Å; L199-F232 HydrophobicContact CG-CD2 3.91Å; L199-F232 HydrophobicContact CG-CE2 3.6Å; L199-F232 HydrophobicContact CG-CZ 4.3Å; L199-T235 HydrophobicContact CD1-CG2 3.86Å; L199-L236 HydrophobicContact CD1-CB 3.87Å; L199-L236 HydrophobicContact CD1-CD1 4.13Å; L199-L236 HydrophobicContact CD2-CD1 4.04Å; L199-L239 HydrophobicContact CD2-CD2 4.33Å
200	V	98.9	Very high	98.6	Very high	21 Å²	21	14.8 Å²	14.8	13%	0.127	9%	0.087	C	C	.	.	H	α-helix	trans	-66.4	-43.7	177	178.5	0	0	0	0	111.2	G196 Q197 A203 S204 L384 Q387 I388	G196-V200 PolarHBondContact O-N 3.12Å; Q197-V200 PolarHBondContact O-N 3.27Å; V200-A203 PolarHBondContact O-N 2.99Å; V200-S204 WeakPolarHBondContact O-CB 3.43Å; V200-S204 PolarHBondContact O-N 3.03Å; V200-S204 PolarHBondContact O-OG 2.71Å; V200-L384 HydrophobicContact CG2-CD2 4.46Å; V200-Q387 HydrophobicContact CB-CB 4.47Å; V200-Q387 HydrophobicContact CB-CG 3.74Å; V200-Q387 HydrophobicContact CG1-CB 4.18Å; V200-Q387 HydrophobicContact CG1-CG 3.57Å; V200-Q387 HydrophobicContact CG2-CG 4.45Å; V200-I388 HydrophobicContact CG1-CB 4.49Å; V200-I388 HydrophobicContact CG1-CG1 3.65Å; V200-I388 HydrophobicContact CG2-CG1 4.07Å
201	I	98.9	Very high	98.4	Very high	0 Å²	0	18 Å²	18	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-62.4	-49.1	178.2	-67.5	166.1	0	0	0	110.4	Q197 S198 A203 S204 I205 F262 F279 Q387	Q197-I201 VanDerWaalsContact O-CG1 3.31Å; Q197-I201 WeakPolarHBondContact O-CG1 3.39Å; Q197-I201 PolarHBondContact O-N 2.97Å; S198-I201 PolarHBondContact O-N 3.37Å; I201-A203 PolarHBondContact O-N 3.46Å; I201-S204 WeakPolarHBondContact O-CB 3.07Å; I201-S204 PolarHBondContact O-N 2.9Å; I201-S204 VanDerWaalsContact O-N 3.13Å; I201-I205 HydrophobicContact CG2-CD1 3.9Å; I201-I205 WeakPolarHBondContact O-CG1 3.46Å; I201-I205 PolarHBondContact O-N 3.45Å; I201-F262 HydrophobicContact CB-CE1 4.24Å; I201-F262 HydrophobicContact CB-CE2 4.35Å; I201-F262 HydrophobicContact CB-CZ 3.88Å; I201-F262 HydrophobicContact CG2-CD1 3.95Å; I201-F262 HydrophobicContact CG2-CD2 4.38Å; I201-F262 HydrophobicContact CG2-CE1 3.61Å; I201-F262 HydrophobicContact CG2-CE2 4.04Å; I201-F262 HydrophobicContact CG2-CG 4.33Å; I201-F262 HydrophobicContact CG2-CZ 3.65Å; I201-F279 HydrophobicContact CD1-CD2 4.13Å; I201-F279 HydrophobicContact CD1-CE2 4.01Å; I201-F279 HydrophobicContact CD1-CG 4.49Å; I201-F279 HydrophobicContact CD1-CZ 4.23Å; I201-F279 HydrophobicContact CG2-CD2 4.16Å; I201-F279 HydrophobicContact CG2-CE2 3.68Å; I201-Q387 HydrophobicContact CG1-CG 4.49Å
202	S	98.9	Very high	98.1	Very high	0 Å²	0	19.3 Å²	19.3	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-62.6	-41.8	178.1	54.9	0	0	0	0	112.4	S198 L199 S204 I205 I206	S198-S202 WeakPolarHBondContact O-CB 3.16Å; S198-S202 PolarHBondContact O-N 3.17Å; S198-S202 PolarHBondContact O-OG 3.21Å; L199-S202 WeakPolarHBondContact CA-OG 3.47Å; L199-S202 PolarHBondContact O-OG 3.44Å; S202-S204 VanDerWaalsContact C-N 3.29Å; S202-S204 PolarHBondContact O-N 3.44Å; S202-I205 PolarHBondContact O-N 2.91Å; S202-I206 VanDerWaalsContact O-CG1 3.26Å; S202-I206 WeakPolarHBondContact O-CG1 3.49Å; S202-I206 PolarHBondContact O-N 2.84Å
203	A	98.9	Very high	97.8	Very high	34 Å²	34	20.6 Å²	20.6	28%	0.281	12%	0.119	S	C	.	.	H	α-helix	trans	-60	-40.3	172.8	0	0	0	0	0	112.2	L199 V200 I201 I206 V207 F232	L199-A203 VanDerWaalsContact O-CB 3.28Å; L199-A203 WeakPolarHBondContact O-CB 3.3Å; L199-A203 PolarHBondContact O-N 3.38Å; V200-A203 PolarHBondContact O-N 2.99Å; I201-A203 PolarHBondContact O-N 3.46Å; A203-I206 PolarHBondContact O-N 2.89Å; A203-V207 WeakPolarHBondContact O-CG2 3.11Å; A203-V207 PolarHBondContact O-N 2.81Å; A203-F232 HydrophobicContact CB-CD2 4.25Å; A203-F232 HydrophobicContact CB-CE2 3.93Å
204	S	98.8	Very high	97.2	Very high	10 Å²	10	28.4 Å²	28.4	7%	0.07	16%	0.155	C	C	.	.	H	α-helix	trans	-65	-42.3	177.4	-53.5	0	0	0	0	111.4	V200 I201 S202 V207 F208 S391 F395	V200-S204 WeakPolarHBondContact O-CB 3.43Å; V200-S204 PolarHBondContact O-N 3.03Å; V200-S204 PolarHBondContact O-OG 2.71Å; I201-S204 WeakPolarHBondContact O-CB 3.07Å; I201-S204 PolarHBondContact O-N 2.9Å; I201-S204 VanDerWaalsContact O-N 3.13Å; S202-S204 VanDerWaalsContact C-N 3.29Å; S202-S204 PolarHBondContact O-N 3.44Å; S204-V207 PolarHBondContact O-N 3.23Å; S204-F208 VanDerWaalsContact O-CB 3.29Å; S204-F208 WeakPolarHBondContact O-CB 3.25Å; S204-F208 PolarHBondContact O-N 3.14Å; S204-S391 VanDerWaalsContact OG-CB 3.23Å; S204-S391 WeakPolarHBondContact OG-CB 3.28Å; S204-S391 PolarHBondContact OG-OG 3.29Å; S204-F395 WeakPolarHBondContact O-CZ 3.35Å
205	I	98.8	Very high	96.5	Very high	0 Å²	0	29.1 Å²	29.1	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-66.4	-39.9	175	-64.1	167.9	0	0	0	110.8	I201 S202 F208 N209 M228 F262 F271 M275 F278	I201-I205 HydrophobicContact CG2-CD1 3.9Å; I201-I205 WeakPolarHBondContact O-CG1 3.46Å; I201-I205 PolarHBondContact O-N 3.45Å; S202-I205 PolarHBondContact O-N 2.91Å; I205-F208 PolarHBondContact O-N 3.31Å; I205-N209 WeakPolarHBondContact O-CB 3.45Å; I205-N209 PolarHBondContact O-N 3.49Å; I205-N209 PolarHBondContact O-ND2 3.17Å; I205-M228 HydrophobicContact CB-CG 4.38Å; I205-M228 HydrophobicContact CB-SD 4.16Å; I205-M228 HydrophobicContact CD1-SD 4.06Å; I205-M228 HydrophobicContact CG2-CG 3.76Å; I205-M228 HydrophobicContact CG2-SD 3.99Å; I205-F262 HydrophobicContact CD1-CD1 3.62Å; I205-F262 HydrophobicContact CD1-CE1 4Å; I205-F271 HydrophobicContact CG2-CE2 4.12Å; I205-F271 HydrophobicContact CG2-CZ 4.3Å; I205-M275 HydrophobicContact CD1-CG 4.15Å; I205-F278 HydrophobicContact CG1-CD2 3.91Å; I205-F278 HydrophobicContact CG1-CE2 4.25Å
206	I	98.8	Very high	95.7	Very high	27 Å²	27	37.4 Å²	37.4	14%	0.138	21%	0.213	C	C	.	.	H	α-helix	trans	-59.9	-50.2	174.8	-71	165.7	0	0	0	110.3	S202 A203 F208 N209 L210 L225 M228 I229 F232	S202-I206 VanDerWaalsContact O-CG1 3.26Å; S202-I206 WeakPolarHBondContact O-CG1 3.49Å; S202-I206 PolarHBondContact O-N 2.84Å; A203-I206 PolarHBondContact O-N 2.89Å; I206-F208 VanDerWaalsContact C-N 3.33Å; I206-F208 PolarHBondContact O-N 3.27Å; I206-N209 PolarHBondContact O-N 2.9Å; I206-L210 HydrophobicContact CG2-CD1 3.96Å; I206-L210 HydrophobicContact CG2-CG 4.37Å; I206-L210 VanDerWaalsContact O-CG 3.28Å; I206-L210 WeakPolarHBondContact O-CG 3.5Å; I206-L210 PolarHBondContact O-N 2.9Å; I206-L225 HydrophobicContact CB-CD2 4.29Å; I206-L225 HydrophobicContact CG1-CD2 4.24Å; I206-L225 HydrophobicContact CG2-CD2 3.96Å; I206-M228 HydrophobicContact CD1-CB 4.23Å; I206-M228 HydrophobicContact CG1-CB 3.67Å; I206-I229 HydrophobicContact CD1-CG1 4.43Å; I206-F232 HydrophobicContact CD1-CB 3.87Å; I206-F232 HydrophobicContact CD1-CD2 4.46Å; I206-F232 HydrophobicContact CD1-CG 4.21Å
207	V	98.4	Very high	95.2	Very high	72 Å²	72	40.6 Å²	40.6	44%	0.436	23%	0.234	S	C	.	.	H	α-helix	trans	-60.3	-45	177.8	171.1	0	0	0	0	110.6	A203 S204 N209 L210 V211 F395	A203-V207 WeakPolarHBondContact O-CG2 3.11Å; A203-V207 PolarHBondContact O-N 2.81Å; S204-V207 PolarHBondContact O-N 3.23Å; V207-N209 PolarHBondContact O-N 2.9Å; V207-L210 PolarHBondContact O-N 3.37Å; V207-V211 WeakPolarHBondContact O-CG2 3.37Å; V207-V211 PolarHBondContact O-N 3.22Å; V207-F395 HydrophobicContact CB-CZ 4.01Å; V207-F395 HydrophobicContact CG1-CE1 4.37Å; V207-F395 HydrophobicContact CG1-CE2 4.31Å; V207-F395 HydrophobicContact CG1-CZ 3.75Å
208	F	97.6	Very high	94.9	Very high	1 Å²	1	46.4 Å²	46.4	0%	0.004	26%	0.256	C	S	.	.	H	α-helix	trans	-57.1	-50.1	175.7	172.5	-115	0	0	0	111.8	S204 I205 I206 L210 V211 E212 H221 F271 T274 F278 F395 R398 Y399	S204-F208 VanDerWaalsContact O-CB 3.29Å; S204-F208 WeakPolarHBondContact O-CB 3.25Å; S204-F208 PolarHBondContact O-N 3.14Å; I205-F208 PolarHBondContact O-N 3.31Å; I206-F208 VanDerWaalsContact C-N 3.33Å; I206-F208 PolarHBondContact O-N 3.27Å; F208-L210 VanDerWaalsContact C-N 3.34Å; F208-L210 PolarHBondContact O-N 3.36Å; F208-V211 PolarHBondContact O-N 3.05Å; F208-E212 HydrophobicContact CD2-CG 3.9Å; F208-E212 HydrophobicContact CE1-CG 4.37Å; F208-E212 HydrophobicContact CE2-CG 3.44Å; F208-E212 VanDerWaalsContact CE2-CG 3.44Å; F208-E212 WeakPolarHBondContact CE2-OE1 3.38Å; F208-E212 HydrophobicContact CZ-CG 3.71Å; F208-E212 WeakPolarHBondContact O-CG 3.35Å; F208-E212 PolarHBondContact O-N 3.49Å; F208-H221 AromaticContact CE1-CE1 3.46Å; F208-H221 VanDerWaalsContact CE1-CE1 3.46Å; F208-H221 WeakPolarHBondContact CE1-CE1 3.39Å; F208-H221 AromaticContact CZ-CE1 3.77Å; F208-F271 HydrophobicContact CD1-CD2 4.5Å; F208-F271 HydrophobicContact CD1-CG 4.43Å; F208-F271 HydrophobicContact CE1-CB 3.69Å; F208-F271 AromaticContact CE1-CD1 3.95Å; F208-F271 HydrophobicContact CE1-CD1 3.95Å; F208-F271 HydrophobicContact CE1-CD2 4.06Å; F208-F271 AromaticContact CE1-CG 3.63Å; F208-F271 HydrophobicContact CE1-CG 3.63Å; F208-F271 HydrophobicContact CZ-CB 4.15Å; F208-T274 HydrophobicContact CD1-CG2 4.5Å; F208-T274 HydrophobicContact CD2-CG2 4.28Å; F208-T274 HydrophobicContact CE1-CG2 4.27Å; F208-T274 HydrophobicContact CE2-CG2 4.07Å; F208-T274 HydrophobicContact CZ-CG2 4.07Å; F208-F278 HydrophobicContact CB-CE2 4.14Å; F208-F278 HydrophobicContact CB-CZ 4.14Å; F208-F278 HydrophobicContact CG-CE2 4.37Å; F208-F395 HydrophobicContact CB-CE1 3.82Å; F208-F395 HydrophobicContact CB-CZ 4.14Å; F208-F395 HydrophobicContact CD2-CE1 4.4Å; F208-R398 HydrophobicContact CE2-CG 4.19Å; F208-Y399 WeakPolarHBondContact CD2-OH 3.29Å
209	N	97.6	Very high	94.5	Very high	0 Å²	0	51.8 Å²	51.8	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-60	-44.4	177.8	-67.6	-28	0	0	0	111.8	I205 I206 V207 V211 E212 L213 H221 S224 L225	I205-N209 WeakPolarHBondContact O-CB 3.45Å; I205-N209 PolarHBondContact O-N 3.49Å; I205-N209 PolarHBondContact O-ND2 3.17Å; I206-N209 PolarHBondContact O-N 2.9Å; V207-N209 PolarHBondContact O-N 2.9Å; N209-V211 VanDerWaalsContact C-N 3.27Å; N209-V211 PolarHBondContact O-N 3.4Å; N209-E212 CarbonylContact O-C 3.42Å; N209-E212 PolarHBondContact O-N 2.82Å; N209-E212 VanDerWaalsContact O-N 3.17Å; N209-L213 WeakPolarHBondContact O-CG 3.41Å; N209-L213 PolarHBondContact O-N 3.11Å; N209-H221 HydrophobicContact CB-CB 4.04Å; N209-H221 PolarHBondContact OD1-ND1 3.27Å; N209-S224 VanDerWaalsContact ND2-CB 3.29Å; N209-S224 WeakPolarHBondContact ND2-CB 3.41Å; N209-S224 PolarHBondContact ND2-OG 3.01Å; N209-S224 PolarHBondContact OD1-OG 3.04Å; N209-L225 HydrophobicContact CB-CD1 4Å; N209-L225 HydrophobicContact CB-CD2 3.83Å; N209-L225 HydrophobicContact CB-CG 3.63Å
210	L	96.3	Very high	94.3	Very high	80 Å²	80	52 Å²	52	42%	0.419	29%	0.286	S	S	.	.	H	α-helix	trans	-60.8	-36.4	179.4	-71.7	173.4	0	0	0	112.2	I206 V207 F208 L213 L225	I206-L210 HydrophobicContact CG2-CD1 3.96Å; I206-L210 HydrophobicContact CG2-CG 4.37Å; I206-L210 VanDerWaalsContact O-CG 3.28Å; I206-L210 WeakPolarHBondContact O-CG 3.5Å; I206-L210 PolarHBondContact O-N 2.9Å; V207-L210 PolarHBondContact O-N 3.37Å; F208-L210 VanDerWaalsContact C-N 3.34Å; F208-L210 PolarHBondContact O-N 3.36Å; L210-L213 HydrophobicContact CD2-CD1 3.94Å; L210-L225 HydrophobicContact CD2-CD1 4.08Å; L210-L225 HydrophobicContact CG-CD2 4.47Å
211	V	94.4	Very high	94.2	Very high	71 Å²	71	51.3 Å²	51.3	43%	0.43	28%	0.281	S	S	.	.	H	α-helix	trans	-69.2	-43.3	174.4	174.5	0	0	0	0	111	V207 F208 N209 L213 Y399	V207-V211 WeakPolarHBondContact O-CG2 3.37Å; V207-V211 PolarHBondContact O-N 3.22Å; F208-V211 PolarHBondContact O-N 3.05Å; N209-V211 VanDerWaalsContact C-N 3.27Å; N209-V211 PolarHBondContact O-N 3.4Å; V211-L213 VanDerWaalsContact C-N 3.27Å; V211-L213 PolarHBondContact O-N 3.29Å; V211-Y399 HydrophobicContact CG1-CE1 3.9Å; V211-Y399 HydrophobicContact CG1-CE2 4.23Å; V211-Y399 VanDerWaalsContact CG1-OH 3.25Å; V211-Y399 WeakPolarHBondContact CG1-OH 3.4Å
212	E	93.8	Very high	94	Very high	32 Å²	32	52 Å²	52	15%	0.15	29%	0.285	C	S	.	.	H	α-helix	trans	-79.3	-4.7	-178.7	-53.3	-79.6	135.1	0	0	113.4	F208 N209 E214 G215 H221 R398 Y399	F208-E212 HydrophobicContact CD2-CG 3.9Å; F208-E212 HydrophobicContact CE1-CG 4.37Å; F208-E212 HydrophobicContact CE2-CG 3.44Å; F208-E212 VanDerWaalsContact CE2-CG 3.44Å; F208-E212 WeakPolarHBondContact CE2-OE1 3.38Å; F208-E212 HydrophobicContact CZ-CG 3.71Å; F208-E212 WeakPolarHBondContact O-CG 3.35Å; F208-E212 PolarHBondContact O-N 3.49Å; N209-E212 CarbonylContact O-C 3.42Å; N209-E212 PolarHBondContact O-N 2.82Å; N209-E212 VanDerWaalsContact O-N 3.17Å; E212-E214 PolarHBondContact O-N 3.25Å; E212-G215 PolarHBondContact O-N 3.35Å; E212-H221 WeakPolarHBondContact CB-CD2 3.23Å; E212-H221 WeakPolarHBondContact CB-NE2 3.36Å; E212-R398 IonicContact OE1-NE 3.59Å; E212-R398 IonicContact OE1-NH2 2.66Å; E212-R398 IonicContact OE2-CZ 3.99Å; E212-R398 IonicContact OE2-NH2 2.97Å; E212-R398 PolarHBondContact OE2-NH2 2.89Å; E212-Y399 WeakPolarHBondContact OE1-CE1 3.45Å; E212-Y399 VanDerWaalsContact OE1-CZ 3.27Å; E212-Y399 PolarHBondContact OE1-OH 3.21Å
213	L	91.8	Very high	93.9	Very high	28 Å²	28	53 Å²	53	15%	0.147	29%	0.29	C	S	.	.	T	Hydrogen-bonded Turn	trans	-62.7	-23.9	173	-79.9	-175.7	0	0	0	113.1	L11 N209 L210 V211 G215 R218 H221 V222 L225	L11-L213 HydrophobicContact CD1-CD1 4.47Å; N209-L213 WeakPolarHBondContact O-CG 3.41Å; N209-L213 PolarHBondContact O-N 3.11Å; L210-L213 HydrophobicContact CD2-CD1 3.94Å; V211-L213 VanDerWaalsContact C-N 3.27Å; V211-L213 PolarHBondContact O-N 3.29Å; L213-G215 VanDerWaalsContact C-N 3.32Å; L213-R218 HydrophobicContact CD2-CG 4.09Å; L213-H221 HydrophobicContact CD2-CB 4.14Å; L213-V222 HydrophobicContact CD2-CB 4.44Å; L213-V222 HydrophobicContact CD2-CG2 3.37Å; L213-L225 HydrophobicContact CD1-CD1 3.85Å; L213-L225 HydrophobicContact CD2-CD1 4.23Å; L213-L225 HydrophobicContact CG-CD1 4.2Å
214	E	86.8	Confident	93.9	Very high	165 Å²	165	51.3 Å²	51.3	77%	0.771	28%	0.276	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.9	-7.1	174.8	-60.8	-169.5	162	0	0	112.8	E212	E212-E214 PolarHBondContact O-N 3.25Å
215	G	83.8	Confident	93.9	Very high	37 Å²	37	50.9 Å²	50.9	38%	0.381	27%	0.273	S	S	.	.	S	Bend	trans	-96.7	-174	-177.2	0	0	0	0	0	114.7	E212 L213 C217	E212-G215 PolarHBondContact O-N 3.35Å; L213-G215 VanDerWaalsContact C-N 3.32Å; G215-C217 PolarHBondContact O-N 3.15Å
216	D	81.5	Confident	93.9	Very high	174 Å²	174	52.1 Å²	52.1	93%	0.93	28%	0.278	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.8	-28.6	-173.4	-62.7	-34.8	0	0	0	113.8	R218	D216-R218 VanDerWaalsContact C-N 3.33Å; D216-R218 PolarHBondContact O-N 3.3Å
217	C	89.2	Confident	93.9	Very high	69 Å²	69	50.8 Å²	50.8	47%	0.466	27%	0.271	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.6	35.6	-175.6	-61.9	0	0	0	0	113.1	G215 D219 D220 H221	G215-C217 PolarHBondContact O-N 3.15Å; C217-D219 VanDerWaalsContact C-N 3.33Å; C217-D219 PolarHBondContact O-N 2.87Å; C217-D220 PolarHBondContact O-N 3.34Å; C217-H221 PolarHBondContact O-CD2 3.13Å; C217-H221 PolarHBondContact O-N 3.04Å
218	R	91.8	Very high	93.9	Very high	126 Å²	126	47.4 Å²	47.4	48%	0.475	25%	0.25	S	S	.	.	H	α-helix	trans	-54.3	-43.5	-172.2	-177.3	178.5	175.6	-142.6	2.5	113.8	L213 D216 D220 H221 V222	L213-R218 HydrophobicContact CD2-CG 4.09Å; D216-R218 VanDerWaalsContact C-N 3.33Å; D216-R218 PolarHBondContact O-N 3.3Å; R218-D220 VanDerWaalsContact C-N 3.33Å; R218-D220 PolarHBondContact O-N 2.67Å; R218-H221 PolarHBondContact O-N 3.37Å; R218-V222 HydrophobicContact CG-CG2 4.16Å; R218-V222 WeakPolarHBondContact O-CG2 3.28Å; R218-V222 PolarHBondContact O-N 3.45Å
219	D	91.4	Very high	94	Very high	112 Å²	112	48.2 Å²	48.2	60%	0.599	26%	0.255	S	S	*	.	H	α-helix	trans	-63.3	-38.7	-175	-63.9	-26.4	0	0	0	112.1	C217 H221 V222 F223	C217-D219 VanDerWaalsContact C-N 3.33Å; C217-D219 PolarHBondContact O-N 2.87Å; D219-H221 VanDerWaalsContact C-N 3.35Å; D219-H221 PolarHBondContact O-N 2.95Å; D219-V222 PolarHBondContact O-N 3.35Å; D219-F223 WeakPolarHBondContact O-CB 3.42Å; D219-F223 PolarHBondContact O-N 2.93Å
220	D	93.9	Very high	94	Very high	34 Å²	34	48.2 Å²	48.2	18%	0.182	26%	0.255	C	S	.	.	H	α-helix	trans	-62.6	-41.2	176.3	-65.2	-14.4	0	0	0	111.6	C217 R218 S224 H270	C217-D220 PolarHBondContact O-N 3.34Å; R218-D220 VanDerWaalsContact C-N 3.33Å; R218-D220 PolarHBondContact O-N 2.67Å; D220-S224 WeakPolarHBondContact O-CB 2.85Å; D220-S224 PolarHBondContact O-N 2.83Å; D220-H270 IonicContact OD2-CD2 3.64Å
221	H	96.3	Very high	94.2	Very high	6 Å²	6	44.4 Å²	44.4	3%	0.028	24%	0.235	C	C	.	.	H	α-helix	trans	-76.3	-35.4	-179.9	-68.6	-64.1	0	0	0	112.6	F208 N209 E212 L213 C217 R218 D219 S224 L225 F271	F208-H221 AromaticContact CE1-CE1 3.46Å; F208-H221 VanDerWaalsContact CE1-CE1 3.46Å; F208-H221 WeakPolarHBondContact CE1-CE1 3.39Å; F208-H221 AromaticContact CZ-CE1 3.77Å; N209-H221 HydrophobicContact CB-CB 4.04Å; N209-H221 PolarHBondContact OD1-ND1 3.27Å; E212-H221 WeakPolarHBondContact CB-CD2 3.23Å; E212-H221 WeakPolarHBondContact CB-NE2 3.36Å; L213-H221 HydrophobicContact CD2-CB 4.14Å; C217-H221 PolarHBondContact O-CD2 3.13Å; C217-H221 PolarHBondContact O-N 3.04Å; R218-H221 PolarHBondContact O-N 3.37Å; D219-H221 VanDerWaalsContact C-N 3.35Å; D219-H221 PolarHBondContact O-N 2.95Å; H221-S224 PolarHBondContact O-N 3.14Å; H221-L225 VanDerWaalsContact O-CG 3.31Å; H221-L225 WeakPolarHBondContact O-CG 3.37Å; H221-L225 PolarHBondContact O-N 3.26Å; H221-F271 AromaticContact CE1-CD1 3.7Å; H221-F271 AromaticContact ND1-CD1 3.98Å
222	V	96.2	Very high	94.4	Very high	14 Å²	14	43 Å²	43	9%	0.085	22%	0.223	C	C	.	.	H	α-helix	trans	-62.2	-46.4	169.9	172	0	0	0	0	110.2	L213 R218 D219 S224 L225 Y226	L213-V222 HydrophobicContact CD2-CB 4.44Å; L213-V222 HydrophobicContact CD2-CG2 3.37Å; R218-V222 HydrophobicContact CG-CG2 4.16Å; R218-V222 WeakPolarHBondContact O-CG2 3.28Å; R218-V222 PolarHBondContact O-N 3.45Å; D219-V222 PolarHBondContact O-N 3.35Å; V222-S224 VanDerWaalsContact C-N 3.35Å; V222-S224 PolarHBondContact O-N 2.98Å; V222-L225 WeakPolarHBondContact O-CB 3.48Å; V222-L225 PolarHBondContact O-N 2.94Å; V222-Y226 HydrophobicContact CG1-CD1 4.48Å; V222-Y226 HydrophobicContact CG1-CE1 3.7Å; V222-Y226 HydrophobicContact CG1-CE2 3.85Å; V222-Y226 VanDerWaalsContact CG1-OH 3.27Å; V222-Y226 WeakPolarHBondContact CG1-OH 3.48Å; V222-Y226 PolarHBondContact O-N 3.06Å
223	F	96.4	Very high	94.6	Very high	20 Å²	20	43.2 Å²	43.2	9%	0.088	22%	0.223	C	C	.	.	H	α-helix	trans	-56.2	-48.7	174.9	174	-90.8	0	0	0	111.4	A97 A101 D219 L225 Y226 F227 L268	A97-F223 HydrophobicContact CB-CE2 3.87Å; A97-F223 HydrophobicContact CB-CZ 4.34Å; A101-F223 HydrophobicContact CB-CZ 4.04Å; D219-F223 WeakPolarHBondContact O-CB 3.42Å; D219-F223 PolarHBondContact O-N 2.93Å; F223-L225 VanDerWaalsContact C-N 3.34Å; F223-L225 PolarHBondContact O-N 2.93Å; F223-Y226 VanDerWaalsContact O-CB 3.32Å; F223-Y226 WeakPolarHBondContact O-CB 3.27Å; F223-Y226 PolarHBondContact O-N 2.96Å; F223-Y226 VanDerWaalsContact O-N 3.1Å; F223-F227 HydrophobicContact CD1-CE2 4.49Å; F223-F227 HydrophobicContact CD2-CE2 4.22Å; F223-F227 HydrophobicContact CE1-CD2 4.16Å; F223-F227 AromaticContact CE1-CE2 3.88Å; F223-F227 HydrophobicContact CE1-CE2 3.88Å; F223-F227 AromaticContact CE2-CE2 3.59Å; F223-F227 HydrophobicContact CE2-CE2 3.59Å; F223-F227 HydrophobicContact CE2-CZ 4.33Å; F223-F227 HydrophobicContact CZ-CD2 4.12Å; F223-F227 AromaticContact CZ-CE2 3.38Å; F223-F227 HydrophobicContact CZ-CE2 3.38Å; F223-F227 HydrophobicContact CZ-CZ 4.07Å; F223-F227 WeakPolarHBondContact O-CD2 3.36Å; F223-L268 HydrophobicContact CD1-CB 4.27Å; F223-L268 HydrophobicContact CE1-CB 3.62Å; F223-L268 HydrophobicContact CE1-CD1 3.88Å; F223-L268 HydrophobicContact CE1-CG 4.39Å; F223-L268 HydrophobicContact CZ-CB 4.13Å; F223-L268 HydrophobicContact CZ-CD1 3.58Å
224	S	98.4	Very high	95	Very high	0 Å²	0	41.9 Å²	41.9	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-59.3	-42.1	177	178.9	0	0	0	0	112.6	N209 D220 H221 V222 Y226 F227 M228 F271	N209-S224 VanDerWaalsContact ND2-CB 3.29Å; N209-S224 WeakPolarHBondContact ND2-CB 3.41Å; N209-S224 PolarHBondContact ND2-OG 3.01Å; N209-S224 PolarHBondContact OD1-OG 3.04Å; D220-S224 WeakPolarHBondContact O-CB 2.85Å; D220-S224 PolarHBondContact O-N 2.83Å; H221-S224 PolarHBondContact O-N 3.14Å; V222-S224 VanDerWaalsContact C-N 3.35Å; V222-S224 PolarHBondContact O-N 2.98Å; S224-Y226 VanDerWaalsContact C-N 3.27Å; S224-Y226 PolarHBondContact O-N 3.1Å; S224-F227 PolarHBondContact O-N 3.01Å; S224-M228 WeakPolarHBondContact O-CB 3.41Å; S224-M228 VanDerWaalsContact O-CG 3.3Å; S224-M228 WeakPolarHBondContact O-CG 3.27Å; S224-M228 PolarHBondContact O-N 3.37Å; S224-F271 WeakPolarHBondContact OG-CZ 3.46Å
225	L	98.6	Very high	95.5	Very high	1 Å²	1	34 Å²	34	1%	0.005	18%	0.18	C	C	.	.	H	α-helix	trans	-62.6	-31.3	175.7	-74.6	168.1	0	0	0	112.9	L11 N14 I206 N209 L210 L213 H221 V222 F223 F227 I229	L11-L225 HydrophobicContact CD1-CD1 4.08Å; L11-L225 HydrophobicContact CD2-CB 3.68Å; L11-L225 HydrophobicContact CD2-CD1 4.37Å; N14-L225 PolarHBondContact ND2-O 3.27Å; I206-L225 HydrophobicContact CB-CD2 4.29Å; I206-L225 HydrophobicContact CG1-CD2 4.24Å; I206-L225 HydrophobicContact CG2-CD2 3.96Å; N209-L225 HydrophobicContact CB-CD1 4Å; N209-L225 HydrophobicContact CB-CD2 3.83Å; N209-L225 HydrophobicContact CB-CG 3.63Å; L210-L225 HydrophobicContact CD2-CD1 4.08Å; L210-L225 HydrophobicContact CG-CD2 4.47Å; L213-L225 HydrophobicContact CD1-CD1 3.85Å; L213-L225 HydrophobicContact CD2-CD1 4.23Å; L213-L225 HydrophobicContact CG-CD1 4.2Å; H221-L225 VanDerWaalsContact O-CG 3.31Å; H221-L225 WeakPolarHBondContact O-CG 3.37Å; H221-L225 PolarHBondContact O-N 3.26Å; V222-L225 WeakPolarHBondContact O-CB 3.48Å; V222-L225 PolarHBondContact O-N 2.94Å; F223-L225 VanDerWaalsContact C-N 3.34Å; F223-L225 PolarHBondContact O-N 2.93Å; L225-F227 PolarHBondContact O-N 3.22Å; L225-I229 HydrophobicContact CB-CD1 4.18Å; L225-I229 HydrophobicContact CD2-CD1 4.23Å; L225-I229 HydrophobicContact CD2-CG1 4.27Å; L225-I229 WeakPolarHBondContact O-CG1 3.41Å; L225-I229 PolarHBondContact O-N 2.99Å
226	Y	98.6	Very high	96.3	Very high	25 Å²	25	34.9 Å²	34.9	10%	0.098	18%	0.175	C	C	.	.	H	α-helix	trans	-56.8	-39.4	174.9	-64	-27.7	0	0	0	112.3	P10 L11 N14 L70 F73 P77 V222 F223 S224 P230	P10-Y226 HydrophobicContact CB-CE1 3.97Å; L11-Y226 HydrophobicContact CD2-CD1 3.69Å; L11-Y226 HydrophobicContact CD2-CE1 3.64Å; L11-Y226 HydrophobicContact CG-CE1 4.14Å; N14-Y226 WeakPolarHBondContact ND2-CA 3.49Å; N14-Y226 PolarHBondContact ND2-O 2.94Å; N14-Y226 VanDerWaalsContact ND2-O 3.1Å; L70-Y226 WeakPolarHBondContact CD2-O 3.28Å; F73-Y226 AromaticContact CE1-CD1 3.49Å; F73-Y226 HydrophobicContact CE1-CD1 3.49Å; F73-Y226 VanDerWaalsContact CE1-CD1 3.49Å; F73-Y226 HydrophobicContact CE1-CD2 4.16Å; F73-Y226 AromaticContact CE1-CE1 3.96Å; F73-Y226 HydrophobicContact CE1-CE1 3.96Å; F73-Y226 AromaticContact CE1-CG 3.61Å; F73-Y226 HydrophobicContact CE1-CG 3.61Å; F73-Y226 AromaticContact CZ-CD1 3.56Å; F73-Y226 HydrophobicContact CZ-CD1 3.56Å; F73-Y226 AromaticContact CZ-CE1 3.67Å; F73-Y226 HydrophobicContact CZ-CE1 3.67Å; F73-Y226 HydrophobicContact CZ-CG 4.17Å; P77-Y226 HydrophobicContact CB-CE2 4.06Å; P77-Y226 HydrophobicContact CG-CD2 4.33Å; P77-Y226 HydrophobicContact CG-CE1 4.43Å; P77-Y226 HydrophobicContact CG-CE2 3.76Å; V222-Y226 HydrophobicContact CG1-CD1 4.48Å; V222-Y226 HydrophobicContact CG1-CE1 3.7Å; V222-Y226 HydrophobicContact CG1-CE2 3.85Å; V222-Y226 VanDerWaalsContact CG1-OH 3.27Å; V222-Y226 WeakPolarHBondContact CG1-OH 3.48Å; V222-Y226 PolarHBondContact O-N 3.06Å; F223-Y226 VanDerWaalsContact O-CB 3.32Å; F223-Y226 WeakPolarHBondContact O-CB 3.27Å; F223-Y226 PolarHBondContact O-N 2.96Å; F223-Y226 VanDerWaalsContact O-N 3.1Å; S224-Y226 VanDerWaalsContact C-N 3.27Å; S224-Y226 PolarHBondContact O-N 3.1Å; Y226-P230 WeakPolarHBondContact O-CD 3.4Å; Y226-P230 VanDerWaalsContact O-CG 3.31Å; Y226-P230 WeakPolarHBondContact O-CG 3.21Å
227	F	98.9	Very high	97.1	Very high	0 Å²	0	26.6 Å²	26.6	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-88.7	-39.5	178.5	-67.1	-93.7	0	0	0	113.1	F66 L70 L98 A101 L102 I105 F223 S224 L225 I229 P230 F231 T261 V265	F66-F227 WeakPolarHBondContact CE2-O 3.04Å; F66-F227 HydrophobicContact CZ-CD1 4.09Å; L70-F227 HydrophobicContact CD1-CD1 3.58Å; L70-F227 HydrophobicContact CD1-CE1 3.79Å; L70-F227 HydrophobicContact CD1-CG 4.43Å; L98-F227 HydrophobicContact CD1-CE2 3.66Å; L98-F227 HydrophobicContact CD1-CZ 3.62Å; L98-F227 HydrophobicContact CG-CZ 4.49Å; A101-F227 HydrophobicContact CB-CE1 3.8Å; A101-F227 HydrophobicContact CB-CE2 4.16Å; A101-F227 HydrophobicContact CB-CZ 3.4Å; A101-F227 VanDerWaalsContact CB-CZ 3.4Å; L102-F227 HydrophobicContact CD2-CE1 4.27Å; L102-F227 HydrophobicContact CG-CE1 4.04Å; L102-F227 HydrophobicContact CG-CZ 4.49Å; I105-F227 HydrophobicContact CD1-CD1 3.68Å; I105-F227 HydrophobicContact CD1-CE1 3.89Å; F223-F227 HydrophobicContact CD1-CE2 4.49Å; F223-F227 HydrophobicContact CD2-CE2 4.22Å; F223-F227 HydrophobicContact CE1-CD2 4.16Å; F223-F227 AromaticContact CE1-CE2 3.88Å; F223-F227 HydrophobicContact CE1-CE2 3.88Å; F223-F227 AromaticContact CE2-CE2 3.59Å; F223-F227 HydrophobicContact CE2-CE2 3.59Å; F223-F227 HydrophobicContact CE2-CZ 4.33Å; F223-F227 HydrophobicContact CZ-CD2 4.12Å; F223-F227 AromaticContact CZ-CE2 3.38Å; F223-F227 HydrophobicContact CZ-CE2 3.38Å; F223-F227 HydrophobicContact CZ-CZ 4.07Å; F223-F227 WeakPolarHBondContact O-CD2 3.36Å; S224-F227 PolarHBondContact O-N 3.01Å; L225-F227 PolarHBondContact O-N 3.22Å; F227-I229 PolarHBondContact O-N 3.21Å; F227-P230 WeakPolarHBondContact O-CD 3.33Å; F227-F231 VanDerWaalsContact O-CB 3.24Å; F227-F231 WeakPolarHBondContact O-CB 3.21Å; F227-F231 PolarHBondContact O-N 2.79Å; F227-F231 VanDerWaalsContact O-N 3.12Å; F227-T261 HydrophobicContact CB-CG2 4.43Å; F227-V265 HydrophobicContact CB-CG1 3.7Å; F227-V265 HydrophobicContact CD2-CG1 4.35Å; F227-V265 HydrophobicContact CG-CG1 4.22Å
228	M	98.9	Very high	97.6	Very high	0 Å²	0	23.3 Å²	23.3	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-69.9	-35.3	-172.6	-70.1	-68.9	99.4	0	0	113.3	I205 I206 S224 F231 F232 T261 F262 V265	I205-M228 HydrophobicContact CB-CG 4.38Å; I205-M228 HydrophobicContact CB-SD 4.16Å; I205-M228 HydrophobicContact CD1-SD 4.06Å; I205-M228 HydrophobicContact CG2-CG 3.76Å; I205-M228 HydrophobicContact CG2-SD 3.99Å; I206-M228 HydrophobicContact CD1-CB 4.23Å; I206-M228 HydrophobicContact CG1-CB 3.67Å; S224-M228 WeakPolarHBondContact O-CB 3.41Å; S224-M228 VanDerWaalsContact O-CG 3.3Å; S224-M228 WeakPolarHBondContact O-CG 3.27Å; S224-M228 PolarHBondContact O-N 3.37Å; M228-F231 PolarHBondContact O-N 2.89Å; M228-F232 VanDerWaalsContact O-CB 3.31Å; M228-F232 WeakPolarHBondContact O-CB 3.27Å; M228-F232 PolarHBondContact O-N 2.88Å; M228-T261 HydrophobicContact CE-CG2 3.48Å; M228-T261 VanDerWaalsContact CE-CG2 3.48Å; M228-F262 HydrophobicContact CE-CD1 4.02Å; M228-F262 HydrophobicContact CE-CE1 4.23Å; M228-F262 HydrophobicContact SD-CD1 4Å; M228-F262 HydrophobicContact SD-CE1 3.93Å; M228-V265 HydrophobicContact CE-CB 4.41Å; M228-V265 HydrophobicContact CE-CG1 3.82Å; M228-V265 HydrophobicContact CE-CG2 3.7Å; M228-V265 HydrophobicContact CG-CG1 4.36Å; M228-V265 HydrophobicContact CG-CG2 4.28Å; M228-V265 HydrophobicContact SD-CG2 4.02Å
229	I	98.9	Very high	97.9	Very high	19 Å²	19	18.3 Å²	18.3	10%	0.097	9%	0.091	C	C	.	.	H	α-helix	trans	-65.7	-53.5	-179.8	-61.3	168.1	0	0	0	110.9	L11 L15 I206 L225 F227 F231 F232 F233	L11-I229 HydrophobicContact CD2-CD1 4.32Å; L15-I229 HydrophobicContact CD1-CG2 4.14Å; I206-I229 HydrophobicContact CD1-CG1 4.43Å; L225-I229 HydrophobicContact CB-CD1 4.18Å; L225-I229 HydrophobicContact CD2-CD1 4.23Å; L225-I229 HydrophobicContact CD2-CG1 4.27Å; L225-I229 WeakPolarHBondContact O-CG1 3.41Å; L225-I229 PolarHBondContact O-N 2.99Å; F227-I229 PolarHBondContact O-N 3.21Å; I229-F231 VanDerWaalsContact C-N 3.31Å; I229-F231 PolarHBondContact O-N 2.82Å; I229-F232 PolarHBondContact O-N 2.94Å; I229-F233 HydrophobicContact CG2-CD2 3.88Å; I229-F233 HydrophobicContact CG2-CE2 3.89Å; I229-F233 VanDerWaalsContact O-CD2 3.31Å; I229-F233 WeakPolarHBondContact O-CD2 3.24Å; I229-F233 PolarHBondContact O-N 3.34Å; I229-F233 VanDerWaalsContact O-N 3.14Å
230	P	98.9	Very high	98.2	Very high	0 Å²	0	19.1 Å²	19.1	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-58.8	-41.7	174.2	-24.6	32.8	0	0	0	112.6	N14 S18 F66 I69 L70 Y226 F227 F232 F233 T234	N14-P230 VanDerWaalsContact OD1-CG 3.24Å; N14-P230 WeakPolarHBondContact OD1-CG 3.41Å; S18-P230 VanDerWaalsContact OG-CA 3.28Å; S18-P230 WeakPolarHBondContact OG-CA 3.48Å; S18-P230 WeakPolarHBondContact OG-CD 3.39Å; S18-P230 VanDerWaalsContact OG-CG 3.31Å; S18-P230 WeakPolarHBondContact OG-CG 3.12Å; F66-P230 HydrophobicContact CD2-CB 3.73Å; F66-P230 HydrophobicContact CE2-CB 3.91Å; I69-P230 HydrophobicContact CG2-CB 4.04Å; I69-P230 HydrophobicContact CG2-CG 4.05Å; L70-P230 HydrophobicContact CD2-CG 3.94Å; L70-P230 HydrophobicContact CG-CG 4.44Å; Y226-P230 WeakPolarHBondContact O-CD 3.4Å; Y226-P230 VanDerWaalsContact O-CG 3.31Å; Y226-P230 WeakPolarHBondContact O-CG 3.21Å; F227-P230 WeakPolarHBondContact O-CD 3.33Å; P230-F232 VanDerWaalsContact C-N 3.34Å; P230-F232 PolarHBondContact O-N 3.24Å; P230-F233 PolarHBondContact O-N 2.92Å; P230-T234 WeakPolarHBondContact O-CG2 3.22Å; P230-T234 PolarHBondContact O-N 3.18Å; P230-T234 PolarHBondContact O-OG1 3.49Å
231	F	98.9	Very high	98.5	Very high	0 Å²	0	18 Å²	18	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-59	-45.5	178.6	177.1	-91.2	0	0	0	111.6	F66 F227 M228 I229 T234 T235 F254 F257 A258 T261 F262	F66-F231 HydrophobicContact CD2-CB 4.25Å; F66-F231 HydrophobicContact CE2-CB 3.82Å; F227-F231 VanDerWaalsContact O-CB 3.24Å; F227-F231 WeakPolarHBondContact O-CB 3.21Å; F227-F231 PolarHBondContact O-N 2.79Å; F227-F231 VanDerWaalsContact O-N 3.12Å; M228-F231 PolarHBondContact O-N 2.89Å; I229-F231 VanDerWaalsContact C-N 3.31Å; I229-F231 PolarHBondContact O-N 2.82Å; F231-T234 PolarHBondContact O-OG1 3.36Å; F231-T235 WeakPolarHBondContact O-CB 3.47Å; F231-T235 PolarHBondContact O-N 3.25Å; F231-T235 PolarHBondContact O-OG1 3.12Å; F231-F254 HydrophobicContact CZ-CE2 4.47Å; F231-F254 HydrophobicContact CZ-CZ 4.26Å; F231-F257 AromaticContact CD2-CE1 3.81Å; F231-F257 HydrophobicContact CD2-CE1 3.81Å; F231-F257 AromaticContact CD2-CE2 3.91Å; F231-F257 HydrophobicContact CD2-CE2 3.91Å; F231-F257 AromaticContact CD2-CZ 3.43Å; F231-F257 HydrophobicContact CD2-CZ 3.43Å; F231-F257 VanDerWaalsContact CD2-CZ 3.43Å; F231-F257 HydrophobicContact CE2-CD1 4.13Å; F231-F257 AromaticContact CE2-CE1 3.73Å; F231-F257 HydrophobicContact CE2-CE1 3.73Å; F231-F257 HydrophobicContact CE2-CE2 4.26Å; F231-F257 AromaticContact CE2-CZ 3.81Å; F231-F257 HydrophobicContact CE2-CZ 3.81Å; F231-A258 HydrophobicContact CE2-CB 3.88Å; F231-A258 HydrophobicContact CZ-CB 3.62Å; F231-T261 HydrophobicContact CB-CG2 4.26Å; F231-T261 HydrophobicContact CD2-CG2 3.94Å; F231-T261 HydrophobicContact CG-CG2 4.19Å; F231-F262 HydrophobicContact CD1-CE1 4.38Å; F231-F262 HydrophobicContact CD1-CZ 4.35Å; F231-F262 AromaticContact CE1-CE1 3.99Å; F231-F262 HydrophobicContact CE1-CE1 3.99Å; F231-F262 HydrophobicContact CE1-CE2 4.27Å; F231-F262 AromaticContact CE1-CZ 3.53Å; F231-F262 HydrophobicContact CE1-CZ 3.53Å; F231-F262 HydrophobicContact CZ-CE2 4.23Å; F231-F262 AromaticContact CZ-CZ 3.95Å; F231-F262 HydrophobicContact CZ-CZ 3.95Å
232	F	98.9	Very high	98.6	Very high	42 Å²	42	17.8 Å²	17.8	18%	0.184	8%	0.08	C	C	.	.	H	α-helix	trans	-60.1	-49.5	177.9	176.4	-90	0	0	0	111.2	L199 A203 I206 M228 I229 P230 T235 L236	L199-F232 HydrophobicContact CD1-CD2 4.17Å; L199-F232 HydrophobicContact CD1-CE2 4.13Å; L199-F232 HydrophobicContact CD2-CE2 3.85Å; L199-F232 HydrophobicContact CD2-CZ 4.19Å; L199-F232 HydrophobicContact CG-CD2 3.91Å; L199-F232 HydrophobicContact CG-CE2 3.6Å; L199-F232 HydrophobicContact CG-CZ 4.3Å; A203-F232 HydrophobicContact CB-CD2 4.25Å; A203-F232 HydrophobicContact CB-CE2 3.93Å; I206-F232 HydrophobicContact CD1-CB 3.87Å; I206-F232 HydrophobicContact CD1-CD2 4.46Å; I206-F232 HydrophobicContact CD1-CG 4.21Å; M228-F232 VanDerWaalsContact O-CB 3.31Å; M228-F232 WeakPolarHBondContact O-CB 3.27Å; M228-F232 PolarHBondContact O-N 2.88Å; I229-F232 PolarHBondContact O-N 2.94Å; P230-F232 VanDerWaalsContact C-N 3.34Å; P230-F232 PolarHBondContact O-N 3.24Å; F232-T235 PolarHBondContact O-N 3.33Å; F232-L236 HydrophobicContact CE1-CD2 4.23Å; F232-L236 WeakPolarHBondContact O-CB 3.47Å; F232-L236 PolarHBondContact O-N 3.06Å
233	F	98.9	Very high	98.7	Very high	35 Å²	35	20.8 Å²	20.8	15%	0.154	9%	0.09	C	C	.	.	H	α-helix	trans	-71.6	-38.1	-175.8	-81.1	-70.7	0	0	0	113.6	L15 S18 L19 F22 I229 P230 L236 G237	L15-F233 HydrophobicContact CD1-CE2 3.55Å; L15-F233 HydrophobicContact CD1-CZ 3.92Å; S18-F233 VanDerWaalsContact O-CB 3.31Å; S18-F233 WeakPolarHBondContact O-CB 3.45Å; L19-F233 HydrophobicContact CD2-CD1 4Å; L19-F233 HydrophobicContact CD2-CE1 3.39Å; L19-F233 HydrophobicContact CD2-CZ 3.7Å; L19-F233 HydrophobicContact CG-CE1 4.3Å; L19-F233 HydrophobicContact CG-CZ 4.28Å; F22-F233 HydrophobicContact CB-CB 4.09Å; F22-F233 HydrophobicContact CB-CD1 4.14Å; F22-F233 WeakPolarHBondContact CD2-O 3.36Å; I229-F233 HydrophobicContact CG2-CD2 3.88Å; I229-F233 HydrophobicContact CG2-CE2 3.89Å; I229-F233 VanDerWaalsContact O-CD2 3.31Å; I229-F233 WeakPolarHBondContact O-CD2 3.24Å; I229-F233 PolarHBondContact O-N 3.34Å; I229-F233 VanDerWaalsContact O-N 3.14Å; P230-F233 PolarHBondContact O-N 2.92Å; F233-L236 PolarHBondContact O-N 3.35Å; F233-G237 PolarHBondContact O-N 2.9Å; F233-G237 VanDerWaalsContact O-N 3.09Å
234	T	98.9	Very high	98.8	Very high	0 Å²	0	22.8 Å²	22.8	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-70.1	-37.3	174.1	60.1	0	0	0	0	111.4	V65 F66 I69 P230 F231 L236 G237 L238	V65-T234 HydrophobicContact CB-CG2 4.39Å; V65-T234 HydrophobicContact CG1-CG2 3.9Å; F66-T234 HydrophobicContact CB-CG2 4.19Å; I69-T234 HydrophobicContact CD1-CG2 3.81Å; P230-T234 WeakPolarHBondContact O-CG2 3.22Å; P230-T234 PolarHBondContact O-N 3.18Å; P230-T234 PolarHBondContact O-OG1 3.49Å; F231-T234 PolarHBondContact O-OG1 3.36Å; T234-L236 VanDerWaalsContact C-N 3.34Å; T234-L236 PolarHBondContact O-N 2.95Å; T234-G237 PolarHBondContact O-N 2.86Å; T234-L238 PolarHBondContact O-N 3.45Å
235	T	98.9	Very high	98.8	Very high	0 Å²	0	26.7 Å²	26.7	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-65	-38	173	-59.1	0	0	0	0	111.7	A195 L199 F231 F232 G237 L238 L239 F254	A195-T235 HydrophobicContact CB-CG2 4.07Å; A195-T235 WeakPolarHBondContact O-CG2 3.37Å; L199-T235 HydrophobicContact CD1-CG2 3.86Å; F231-T235 WeakPolarHBondContact O-CB 3.47Å; F231-T235 PolarHBondContact O-N 3.25Å; F231-T235 PolarHBondContact O-OG1 3.12Å; F232-T235 PolarHBondContact O-N 3.33Å; T235-G237 VanDerWaalsContact C-N 3.28Å; T235-G237 PolarHBondContact O-N 2.91Å; T235-L238 WeakPolarHBondContact O-CB 3.12Å; T235-L238 PolarHBondContact O-N 3.33Å; T235-L239 WeakPolarHBondContact O-CB 3.28Å; T235-L239 PolarHBondContact O-N 3.08Å; T235-F254 HydrophobicContact CG2-CE2 3.84Å; T235-F254 HydrophobicContact CG2-CZ 3.57Å
236	L	98.9	Very high	98.8	Very high	56 Å²	56	27 Å²	27	29%	0.293	12%	0.124	S	C	.	.	H	α-helix	trans	-61.7	-39.4	174.4	-171.6	60.8	0	0	0	111.3	F22 L199 F232 F233 T234 L239 Y240	F22-L236 HydrophobicContact CD2-CB 4.02Å; F22-L236 HydrophobicContact CD2-CD2 4.23Å; F22-L236 HydrophobicContact CD2-CG 4.07Å; F22-L236 HydrophobicContact CE2-CB 4.18Å; F22-L236 HydrophobicContact CE2-CD2 4.09Å; F22-L236 HydrophobicContact CE2-CG 3.78Å; L199-L236 HydrophobicContact CD1-CB 3.87Å; L199-L236 HydrophobicContact CD1-CD1 4.13Å; L199-L236 HydrophobicContact CD2-CD1 4.04Å; F232-L236 HydrophobicContact CE1-CD2 4.23Å; F232-L236 WeakPolarHBondContact O-CB 3.47Å; F232-L236 PolarHBondContact O-N 3.06Å; F233-L236 PolarHBondContact O-N 3.35Å; T234-L236 VanDerWaalsContact C-N 3.34Å; T234-L236 PolarHBondContact O-N 2.95Å; L236-L239 PolarHBondContact O-N 3.36Å; L236-Y240 PolarHBondContact O-N 2.94Å
237	G	98.9	Very high	98.8	Very high	0 Å²	0	31.1 Å²	31.1	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-66.7	-36	175.6	0	0	0	0	0	112.9	F233 T234 T235 Y240	F233-G237 PolarHBondContact O-N 2.9Å; F233-G237 VanDerWaalsContact O-N 3.09Å; T234-G237 PolarHBondContact O-N 2.86Å; T235-G237 VanDerWaalsContact C-N 3.28Å; T235-G237 PolarHBondContact O-N 2.91Å; G237-Y240 WeakPolarHBondContact O-CB 3.24Å
238	L	98.9	Very high	98.8	Very high	0 Å²	0	31.3 Å²	31.3	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-67.3	-47.2	171.6	178.4	61.6	0	0	0	111.6	I29 Q58 T234 T235 Y240 H241 N242 V248 V250 F254	I29-L238 HydrophobicContact CD1-CB 4.3Å; I29-L238 HydrophobicContact CD1-CD1 3.78Å; Q58-L238 HydrophobicContact CB-CD1 3.75Å; T234-L238 PolarHBondContact O-N 3.45Å; T235-L238 WeakPolarHBondContact O-CB 3.12Å; T235-L238 PolarHBondContact O-N 3.33Å; L238-Y240 PolarHBondContact O-N 3.45Å; L238-H241 PolarHBondContact O-N 2.86Å; L238-N242 WeakPolarHBondContact O-CB 3.31Å; L238-N242 PolarHBondContact O-N 2.74Å; L238-V248 HydrophobicContact CD1-CG2 4.34Å; L238-V250 HydrophobicContact CD1-CG1 4.23Å; L238-V250 HydrophobicContact CD2-CB 4.08Å; L238-V250 HydrophobicContact CD2-CG1 3.67Å; L238-V250 HydrophobicContact CG-CG1 3.95Å; L238-F254 HydrophobicContact CD2-CB 4.4Å; L238-F254 HydrophobicContact CD2-CD2 3.39Å; L238-F254 HydrophobicContact CD2-CE2 3.81Å; L238-F254 HydrophobicContact CD2-CG 3.9Å
239	L	98.9	Very high	98.8	Very high	20 Å²	20	32.6 Å²	32.6	11%	0.105	15%	0.146	C	C	.	.	H	α-helix	trans	-60.4	-32.9	179.1	-171.6	63.9	0	0	0	111.7	A195 L199 T235 L236 H241 N242 W243	A195-L239 HydrophobicContact CB-CB 4.2Å; A195-L239 HydrophobicContact CB-CD1 3.87Å; L199-L239 HydrophobicContact CD2-CD2 4.33Å; T235-L239 WeakPolarHBondContact O-CB 3.28Å; T235-L239 PolarHBondContact O-N 3.08Å; L236-L239 PolarHBondContact O-N 3.36Å; L239-H241 PolarHBondContact O-N 3.4Å; L239-N242 PolarHBondContact O-N 2.84Å; L239-W243 HydrophobicContact CD1-CE3 3.89Å; L239-W243 HydrophobicContact CG-CE3 4.36Å; L239-W243 VanDerWaalsContact O-CB 3.26Å; L239-W243 WeakPolarHBondContact O-CB 3.21Å; L239-W243 PolarHBondContact O-N 3.28Å
240	Y	98.9	Very high	98.8	Very high	129 Å²	129	32 Å²	32	51%	0.506	14%	0.144	S	C	.	.	H	α-helix	trans	-54.2	-35.6	174	178.2	-91.9	0	0	0	113.1	V26 L236 G237 L238 R247	V26-Y240 HydrophobicContact CG1-CD1 3.89Å; V26-Y240 HydrophobicContact CG1-CE1 3.96Å; V26-Y240 HydrophobicContact CG2-CD1 4.34Å; V26-Y240 HydrophobicContact CG2-CG 4.3Å; L236-Y240 PolarHBondContact O-N 2.94Å; G237-Y240 WeakPolarHBondContact O-CB 3.24Å; L238-Y240 PolarHBondContact O-N 3.45Å; Y240-R247 PolarHBondContact O-NH2 3.19Å
241	H	98.8	Very high	98.7	Very high	11 Å²	11	32.3 Å²	32.3	5%	0.051	15%	0.147	C	C	.	.	H	α-helix	trans	-95.2	-25.9	177.4	-65.5	-71.7	0	0	0	113.5	V26 I29 L238 L239 R247 V248	V26-H241 PolarHBondContact O-NE2 2.88Å; I29-H241 HydrophobicContact CG2-CB 4.05Å; L238-H241 PolarHBondContact O-N 2.86Å; L239-H241 PolarHBondContact O-N 3.4Å; H241-R247 PolarHBondContact ND1-NH2 3.21Å; H241-R247 WeakPolarHBondContact O-CB 3.39Å; H241-R247 PolarHBondContact O-N 2.85Å; H241-V248 HydrophobicContact CB-CG1 4.21Å; H241-V248 HydrophobicContact CB-CG2 3.66Å; H241-V248 PolarHBondContact O-N 3.07Å
242	N	98.8	Very high	98.7	Very high	2 Å²	2	33.6 Å²	33.6	1%	0.011	15%	0.154	C	C	.	.	H	α-helix	trans	-90.5	-11.1	-179.6	179.6	-111.7	0	0	0	114	G192 L238 L239 S246 V248 V250	G192-N242 WeakPolarHBondContact CA-OD1 3.4Å; G192-N242 PolarHBondContact N-O 3.28Å; G192-N242 PolarHBondContact N-OD1 3.12Å; L238-N242 WeakPolarHBondContact O-CB 3.31Å; L238-N242 PolarHBondContact O-N 2.74Å; L239-N242 PolarHBondContact O-N 2.84Å; N242-S246 PolarHBondContact O-OG 3.4Å; N242-V248 HydrophobicContact CB-CG2 4.29Å; N242-V248 PolarHBondContact ND2-O 2.65Å; N242-V250 HydrophobicContact CB-CG1 4.17Å
243	W	98.9	Very high	98.6	Very high	77 Å²	77	31.6 Å²	31.6	29%	0.292	15%	0.145	S	C	.	.	S	Bend	trans	-63.4	152.3	175.5	-170.1	-108.5	0	0	0	111.4	L239 P245 S246 R377 T380 L381 L384	L239-W243 HydrophobicContact CD1-CE3 3.89Å; L239-W243 HydrophobicContact CG-CE3 4.36Å; L239-W243 VanDerWaalsContact O-CB 3.26Å; L239-W243 WeakPolarHBondContact O-CB 3.21Å; L239-W243 PolarHBondContact O-N 3.28Å; W243-P245 CarbonylContact O-C 3.55Å; W243-S246 WeakPolarHBondContact O-CA 3.06Å; W243-S246 PolarHBondContact O-N 2.94Å; W243-S246 VanDerWaalsContact O-N 3.15Å; W243-R377 HydrophobicContact CZ2-CG 4.43Å; W243-T380 HydrophobicContact CH2-CG2 4.16Å; W243-T380 HydrophobicContact CZ3-CG2 3.93Å; W243-L381 HydrophobicContact CH2-CD2 3.61Å; W243-L381 HydrophobicContact CH2-CG 3.91Å; W243-L381 HydrophobicContact CZ2-CD1 4.44Å; W243-L381 HydrophobicContact CZ2-CD2 3.74Å; W243-L381 HydrophobicContact CZ2-CG 3.92Å; W243-L384 HydrophobicContact CH2-CD1 4.01Å; W243-L384 HydrophobicContact CZ3-CD1 3.81Å
244	Y	98.5	Very high	98.6	Very high	62 Å²	62	29.9 Å²	29.9	24%	0.243	14%	0.138	C	C	.	.	S	Bend	trans	-58.9	129.9	178.9	-178.1	-83.5	0	0	0	112.1	N191 H375 E376 R377	N191-Y244 HydrophobicContact CB-CD2 4.06Å; Y244-H375 AromaticContact CE1-NE2 3.7Å; Y244-H375 AromaticContact CZ-CE1 3.79Å; Y244-H375 AromaticContact CZ-NE2 3.47Å; Y244-H375 PolarHBondContact OH-CE1 3.32Å; Y244-H375 VanDerWaalsContact OH-CE1 3.25Å; Y244-H375 PolarHBondContact OH-NE2 2.69Å; Y244-E376 HydrophobicContact CD2-CB 4.18Å; Y244-E376 HydrophobicContact CD2-CG 4.1Å; Y244-E376 WeakPolarHBondContact CD2-OE2 3.31Å; Y244-E376 HydrophobicContact CE2-CB 4Å; Y244-E376 HydrophobicContact CE2-CG 4.32Å; Y244-E376 WeakPolarHBondContact CE2-OE2 3.49Å; Y244-R377 HydrophobicContact CD1-CB 3.79Å; Y244-R377 HydrophobicContact CD1-CG 4.16Å; Y244-R377 HydrophobicContact CD2-CB 4.42Å; Y244-R377 HydrophobicContact CE1-CB 4.34Å; Y244-R377 HydrophobicContact CG-CB 3.84Å; Y244-R377 HydrophobicContact CG-CG 4.31Å
245	P	98.3	Very high	98.6	Very high	82 Å²	82	30 Å²	30	53%	0.532	14%	0.138	S	C	.	.	S	Bend	cis	-79.2	126	-7.4	31.1	-32.7	0	0	0	111.9	W243 R247	W243-P245 CarbonylContact O-C 3.55Å; P245-R247 PolarHBondContact O-N 3.39Å
246	S	98.5	Very high	98.6	Very high	6 Å²	6	30 Å²	30	4%	0.042	14%	0.138	C	C	.	.	P	Polyproline II helix	trans	-54.3	128.8	-177.7	-70.9	0	0	0	0	112.7	I54 N191 N242 W243	I54-S246 WeakPolarHBondContact CD1-O 3.45Å; N191-S246 WeakPolarHBondContact CB-OG 3.31Å; N191-S246 WeakPolarHBondContact OD1-CB 3.31Å; N191-S246 PolarHBondContact OD1-OG 3.45Å; N242-S246 PolarHBondContact O-OG 3.4Å; W243-S246 WeakPolarHBondContact O-CA 3.06Å; W243-S246 PolarHBondContact O-N 2.94Å; W243-S246 VanDerWaalsContact O-N 3.15Å
247	R	98.6	Very high	98.6	Very high	112 Å²	112	27.3 Å²	27.3	42%	0.423	12%	0.124	S	C	.	.	S	Bend	trans	-94.7	-17.6	168.6	-65.4	177.4	-75.8	175.7	-3.6	111.9	R33 P55 Y240 H241 P245	R33-R247 PolarHBondContact NH1-O 3.01Å; R33-R247 VanDerWaalsContact NH1-O 3.16Å; P55-R247 WeakPolarHBondContact CD-O 3.46Å; Y240-R247 PolarHBondContact O-NH2 3.19Å; H241-R247 PolarHBondContact ND1-NH2 3.21Å; H241-R247 WeakPolarHBondContact O-CB 3.39Å; H241-R247 PolarHBondContact O-N 2.85Å; P245-R247 PolarHBondContact O-N 3.39Å
248	V	98.8	Very high	98.6	Very high	4 Å²	4	27.3 Å²	27.3	2%	0.024	12%	0.124	C	C	.	.	S	Bend	trans	-148.1	156.5	177.4	-50.2	0	0	0	0	111.3	I29 I54 P55 Q58 L238 H241 N242	I29-V248 HydrophobicContact CG2-CG1 3.67Å; I29-V248 HydrophobicContact CG2-CG2 4.21Å; I54-V248 VanDerWaalsContact CG2-CA 3.43Å; P55-V248 HydrophobicContact CG-CB 4.11Å; P55-V248 HydrophobicContact CG-CG1 3.73Å; Q58-V248 HydrophobicContact CB-CB 4.26Å; Q58-V248 HydrophobicContact CB-CG2 4.04Å; Q58-V248 HydrophobicContact CG-CB 3.46Å; Q58-V248 VanDerWaalsContact CG-CB 3.46Å; Q58-V248 HydrophobicContact CG-CG1 3.9Å; Q58-V248 HydrophobicContact CG-CG2 3.79Å; L238-V248 HydrophobicContact CD1-CG2 4.34Å; H241-V248 HydrophobicContact CB-CG1 4.21Å; H241-V248 HydrophobicContact CB-CG2 3.66Å; H241-V248 PolarHBondContact O-N 3.07Å; N242-V248 HydrophobicContact CB-CG2 4.29Å; N242-V248 PolarHBondContact ND2-O 2.65Å
249	F	98.8	Very high	98.6	Very high	27 Å²	27	27.3 Å²	27.3	12%	0.118	12%	0.124	C	C	.	.			trans	-110.9	152.1	170.2	-60.2	-48.4	0	0	0	111.6	D45 I54 P55 E56 S57 Q58	D45-F249 HydrophobicContact CB-CZ 3.91Å; I54-F249 HydrophobicContact CB-CD2 4.02Å; I54-F249 HydrophobicContact CB-CE2 3.7Å; I54-F249 HydrophobicContact CB-CZ 4.18Å; I54-F249 HydrophobicContact CD1-CE1 4.44Å; I54-F249 HydrophobicContact CD1-CE2 4.21Å; I54-F249 HydrophobicContact CD1-CZ 3.83Å; I54-F249 HydrophobicContact CG1-CE2 4.48Å; I54-F249 HydrophobicContact CG2-CD1 4.37Å; I54-F249 HydrophobicContact CG2-CD2 3.81Å; I54-F249 HydrophobicContact CG2-CE1 4.41Å; I54-F249 HydrophobicContact CG2-CE2 3.86Å; I54-F249 HydrophobicContact CG2-CG 4.07Å; I54-F249 HydrophobicContact CG2-CZ 4.16Å; P55-F249 PolarHBondContact O-N 3.12Å; E56-F249 CarbonylContact C-O 3.52Å; E56-F249 VanDerWaalsContact CD-CB 3.42Å; E56-F249 WeakPolarHBondContact OE1-CB 3.14Å; E56-F249 WeakPolarHBondContact OE2-CB 3.23Å; E56-F249 VanDerWaalsContact OE2-CD2 3.28Å; E56-F249 WeakPolarHBondContact OE2-CD2 3.28Å; S57-F249 PolarHBondContact N-O 3.46Å; Q58-F249 WeakPolarHBondContact CB-O 3.44Å; Q58-F249 PolarHBondContact N-O 3.43Å
250	V	98.7	Very high	98.6	Very high	6 Å²	6	26.4 Å²	26.4	4%	0.036	12%	0.119	C	C	.	.			trans	-82.8	-27.9	-169.4	-54.8	0	0	0	0	113.2	S57 G59 E194 A195 L238 N242 F254	S57-V250 CarbonylContact C-O 3.55Å; S57-V250 WeakPolarHBondContact CA-O 3.41Å; G59-V250 WeakPolarHBondContact CA-O 3.48Å; G59-V250 PolarHBondContact N-O 3.15Å; E194-V250 HydrophobicContact CB-CG2 3.78Å; E194-V250 HydrophobicContact CG-CG2 4.11Å; A195-V250 HydrophobicContact CB-CG1 4.26Å; L238-V250 HydrophobicContact CD1-CG1 4.23Å; L238-V250 HydrophobicContact CD2-CB 4.08Å; L238-V250 HydrophobicContact CD2-CG1 3.67Å; L238-V250 HydrophobicContact CG-CG1 3.95Å; N242-V250 HydrophobicContact CB-CG1 4.17Å; V250-F254 HydrophobicContact CB-CB 3.6Å; V250-F254 HydrophobicContact CB-CD1 4.16Å; V250-F254 HydrophobicContact CB-CG 3.96Å; V250-F254 HydrophobicContact CG2-CB 3.9Å; V250-F254 HydrophobicContact CG2-CD1 4.03Å; V250-F254 HydrophobicContact CG2-CG 4.26Å
251	G	97.8	Very high	98.6	Very high	7 Å²	7	20.2 Å²	20.2	7%	0.072	10%	0.095	C	C	.	.	H	α-helix	trans	69.3	171.2	-174.1	0	0	0	0	0	115.6	E56 D116 T253 F254	E56-G251 VanDerWaalsContact OE1-CA 3.26Å; E56-G251 WeakPolarHBondContact OE1-CA 3.41Å; E56-G251 PolarHBondContact OE1-N 3.04Å; D116-G251 WeakPolarHBondContact OD2-CA 3.44Å; G251-T253 PolarHBondContact O-N 2.97Å; G251-F254 PolarHBondContact O-N 3.25Å; G251-F254 VanDerWaalsContact O-N 3.17Å
252	D	97.3	Very high	98.6	Very high	27 Å²	27	19.7 Å²	19.7	14%	0.144	9%	0.093	C	C	.	.	H	α-helix	trans	-55.9	-32.1	170.2	-74.1	-36.2	0	0	0	110.2	D116 K125 N185 F254 C255 Y256	D116-D252 VanDerWaalsContact OD1-CB 3.28Å; D116-D252 WeakPolarHBondContact OD1-CB 3.47Å; D116-D252 PolarHBondContact OD1-N 3.24Å; D116-D252 PolarHBondContact OD2-N 2.62Å; K125-D252 IonicContact NZ-OD1 2.74Å; K125-D252 IonicContact NZ-OD2 3.69Å; K125-D252 PolarHBondContact NZ-OD2 3.02Å; N185-D252 VanDerWaalsContact CG-OD1 3.26Å; N185-D252 PolarHBondContact ND2-OD1 2.95Å; N185-D252 PolarHBondContact OD1-OD1 3.48Å; D252-F254 VanDerWaalsContact C-N 3.29Å; D252-F254 PolarHBondContact O-N 3.11Å; D252-C255 PolarHBondContact O-N 3.31Å; D252-C255 VanDerWaalsContact O-N 3.16Å; D252-Y256 HydrophobicContact CB-CE1 4.49Å; D252-Y256 WeakPolarHBondContact O-CB 3.33Å; D252-Y256 WeakPolarHBondContact O-CD1 3.37Å; D252-Y256 PolarHBondContact O-N 3.1Å
253	T	98.4	Very high	98.6	Very high	0 Å²	0	19.6 Å²	19.6	0%	0	9%	0.092	C	C	.	.	H	α-helix	trans	-47.7	-48.8	174.9	-53.4	0	0	0	0	112.6	V60 I109 F113 D116 G251 F257	V60-T253 HydrophobicContact CB-CG2 3.92Å; V60-T253 HydrophobicContact CG2-CG2 4.41Å; I109-T253 HydrophobicContact CG2-CG2 4.24Å; F113-T253 WeakPolarHBondContact CA-OG1 3.41Å; F113-T253 HydrophobicContact CB-CG2 4.15Å; F113-T253 PolarHBondContact N-OG1 2.79Å; D116-T253 WeakPolarHBondContact OD2-CB 3.37Å; D116-T253 PolarHBondContact OD2-N 3.23Å; D116-T253 PolarHBondContact OD2-OG1 3.24Å; G251-T253 PolarHBondContact O-N 2.97Å; T253-F257 VanDerWaalsContact O-CB 3.23Å; T253-F257 WeakPolarHBondContact O-CB 3.24Å; T253-F257 PolarHBondContact O-N 2.81Å
254	F	98.9	Very high	98.5	Very high	0 Å²	0	16 Å²	16	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-70.7	-43.6	-179.1	177.9	-98.4	0	0	0	112.1	E194 A195 F231 T235 L238 V250 G251 D252 Y256 F257 A258	E194-F254 HydrophobicContact CB-CD1 4.36Å; A195-F254 HydrophobicContact CB-CE1 4.22Å; A195-F254 HydrophobicContact CB-CZ 4.22Å; F231-F254 HydrophobicContact CZ-CE2 4.47Å; F231-F254 HydrophobicContact CZ-CZ 4.26Å; T235-F254 HydrophobicContact CG2-CE2 3.84Å; T235-F254 HydrophobicContact CG2-CZ 3.57Å; L238-F254 HydrophobicContact CD2-CB 4.4Å; L238-F254 HydrophobicContact CD2-CD2 3.39Å; L238-F254 HydrophobicContact CD2-CE2 3.81Å; L238-F254 HydrophobicContact CD2-CG 3.9Å; V250-F254 HydrophobicContact CB-CB 3.6Å; V250-F254 HydrophobicContact CB-CD1 4.16Å; V250-F254 HydrophobicContact CB-CG 3.96Å; V250-F254 HydrophobicContact CG2-CB 3.9Å; V250-F254 HydrophobicContact CG2-CD1 4.03Å; V250-F254 HydrophobicContact CG2-CG 4.26Å; G251-F254 PolarHBondContact O-N 3.25Å; G251-F254 VanDerWaalsContact O-N 3.17Å; D252-F254 VanDerWaalsContact C-N 3.29Å; D252-F254 PolarHBondContact O-N 3.11Å; F254-Y256 PolarHBondContact O-N 3.29Å; F254-F257 HydrophobicContact CD2-CD1 4.04Å; F254-F257 HydrophobicContact CE2-CD1 4.29Å; F254-F257 WeakPolarHBondContact O-CB 3.31Å; F254-F257 PolarHBondContact O-N 3.43Å; F254-A258 HydrophobicContact CE1-CB 4.11Å; F254-A258 HydrophobicContact CZ-CB 4.13Å; F254-A258 VanDerWaalsContact O-CB 3.29Å; F254-A258 WeakPolarHBondContact O-CB 3.44Å; F254-A258 PolarHBondContact O-N 3.28Å
255	C	98.6	Very high	98.6	Very high	2 Å²	2	13 Å²	13	1%	0.014	7%	0.067	C	C	.	.	H	α-helix	trans	-59.1	-39.8	179.4	-62.8	0	0	0	0	111	I184 N185 D252 G259	I184-C255 HydrophobicContact CG2-CB 4.36Å; N185-C255 HydrophobicContact CB-CB 3.77Å; D252-C255 PolarHBondContact O-N 3.31Å; D252-C255 VanDerWaalsContact O-N 3.16Å; C255-G259 PolarHBondContact O-N 3.2Å
256	Y	98.5	Very high	98.5	Very high	0 Å²	0	9.1 Å²	9.1	0%	0	4%	0.042	C	C	.	.	H	α-helix	trans	-68.5	-50.6	177.7	-83.2	34.6	0	0	0	110.6	M108 D115 K125 T181 D252 F254 A258 G259 M260	M108-Y256 HydrophobicContact CG-CG 4.49Å; M108-Y256 WeakPolarHBondContact CG-O 3.29Å; M108-Y256 VanDerWaalsContact SD-CB 3.54Å; M108-Y256 HydrophobicContact SD-CD2 3.44Å; M108-Y256 WeakPolarHBondContact SD-CD2 3.33Å; M108-Y256 HydrophobicContact SD-CE2 4.45Å; M108-Y256 HydrophobicContact SD-CG 3.72Å; D115-Y256 HydrophobicContact CB-CE2 4.4Å; D115-Y256 PolarHBondContact OD2-OH 2.8Å; K125-Y256 WeakPolarHBondContact CB-OH 3.32Å; K125-Y256 WeakPolarHBondContact CG-OH 3.32Å; T181-Y256 WeakPolarHBondContact CG2-O 3.43Å; D252-Y256 HydrophobicContact CB-CE1 4.49Å; D252-Y256 WeakPolarHBondContact O-CB 3.33Å; D252-Y256 WeakPolarHBondContact O-CD1 3.37Å; D252-Y256 PolarHBondContact O-N 3.1Å; F254-Y256 PolarHBondContact O-N 3.29Å; Y256-A258 PolarHBondContact O-N 3.31Å; Y256-G259 PolarHBondContact O-N 3.49Å; Y256-M260 WeakPolarHBondContact O-CB 3.49Å; Y256-M260 PolarHBondContact O-N 2.93Å
257	F	98.8	Very high	98.5	Very high	0 Å²	0	8.9 Å²	8.9	0%	0	4%	0.04	C	C	.	.	H	α-helix	trans	-52.3	-52.3	173.6	167.6	-138.2	0	0	0	112.6	F66 I105 I109 F231 T253 F254 T261	F66-F257 HydrophobicContact CB-CE2 4.41Å; F66-F257 HydrophobicContact CB-CZ 3.83Å; F66-F257 AromaticContact CD1-CE2 3.58Å; F66-F257 HydrophobicContact CD1-CE2 3.58Å; F66-F257 AromaticContact CD1-CZ 3.83Å; F66-F257 HydrophobicContact CD1-CZ 3.83Å; F66-F257 HydrophobicContact CD2-CE2 4.3Å; F66-F257 AromaticContact CD2-CZ 3.89Å; F66-F257 HydrophobicContact CD2-CZ 3.89Å; F66-F257 AromaticContact CE1-CE2 3.78Å; F66-F257 HydrophobicContact CE1-CE2 3.78Å; F66-F257 HydrophobicContact CE1-CZ 4.32Å; F66-F257 HydrophobicContact CE2-CE2 4.46Å; F66-F257 HydrophobicContact CE2-CZ 4.37Å; F66-F257 AromaticContact CG-CE2 3.85Å; F66-F257 HydrophobicContact CG-CE2 3.85Å; F66-F257 AromaticContact CG-CZ 3.58Å; F66-F257 HydrophobicContact CG-CZ 3.58Å; F66-F257 HydrophobicContact CZ-CE2 4.19Å; I105-F257 HydrophobicContact CG2-CD2 3.73Å; I105-F257 HydrophobicContact CG2-CE2 3.84Å; I109-F257 HydrophobicContact CD1-CD2 3.73Å; I109-F257 HydrophobicContact CD1-CE2 4.13Å; I109-F257 HydrophobicContact CD1-CG 4.25Å; I109-F257 HydrophobicContact CG1-CB 3.77Å; I109-F257 HydrophobicContact CG1-CD2 3.71Å; I109-F257 HydrophobicContact CG1-CG 3.87Å; F231-F257 AromaticContact CD2-CE1 3.81Å; F231-F257 HydrophobicContact CD2-CE1 3.81Å; F231-F257 AromaticContact CD2-CE2 3.91Å; F231-F257 HydrophobicContact CD2-CE2 3.91Å; F231-F257 AromaticContact CD2-CZ 3.43Å; F231-F257 HydrophobicContact CD2-CZ 3.43Å; F231-F257 VanDerWaalsContact CD2-CZ 3.43Å; F231-F257 HydrophobicContact CE2-CD1 4.13Å; F231-F257 AromaticContact CE2-CE1 3.73Å; F231-F257 HydrophobicContact CE2-CE1 3.73Å; F231-F257 HydrophobicContact CE2-CE2 4.26Å; F231-F257 AromaticContact CE2-CZ 3.81Å; F231-F257 HydrophobicContact CE2-CZ 3.81Å; T253-F257 VanDerWaalsContact O-CB 3.23Å; T253-F257 WeakPolarHBondContact O-CB 3.24Å; T253-F257 PolarHBondContact O-N 2.81Å; F254-F257 HydrophobicContact CD2-CD1 4.04Å; F254-F257 HydrophobicContact CE2-CD1 4.29Å; F254-F257 WeakPolarHBondContact O-CB 3.31Å; F254-F257 PolarHBondContact O-N 3.43Å; F257-T261 WeakPolarHBondContact CD2-OG1 3.5Å; F257-T261 VanDerWaalsContact CE2-OG1 3.31Å; F257-T261 WeakPolarHBondContact CE2-OG1 3.29Å; F257-T261 WeakPolarHBondContact O-CB 3.3Å; F257-T261 PolarHBondContact O-N 2.71Å; F257-T261 PolarHBondContact O-OG1 2.99Å
258	A	98.9	Very high	98.4	Very high	0 Å²	0	3.7 Å²	3.7	0%	0	2%	0.021	C	C	.	.	H	α-helix	trans	-62.3	-51.9	-178.8	0	0	0	0	0	111.7	I184 F231 F254 Y256 M260 T261 F262	I184-A258 HydrophobicContact CD1-CB 3.9Å; F231-A258 HydrophobicContact CE2-CB 3.88Å; F231-A258 HydrophobicContact CZ-CB 3.62Å; F254-A258 HydrophobicContact CE1-CB 4.11Å; F254-A258 HydrophobicContact CZ-CB 4.13Å; F254-A258 VanDerWaalsContact O-CB 3.29Å; F254-A258 WeakPolarHBondContact O-CB 3.44Å; F254-A258 PolarHBondContact O-N 3.28Å; Y256-A258 PolarHBondContact O-N 3.31Å; A258-M260 VanDerWaalsContact C-N 3.34Å; A258-M260 PolarHBondContact O-N 2.91Å; A258-T261 PolarHBondContact O-N 2.98Å; A258-F262 HydrophobicContact CB-CE2 4.13Å; A258-F262 WeakPolarHBondContact O-CD2 3.19Å; A258-F262 WeakPolarHBondContact O-CG 3.45Å; A258-F262 PolarHBondContact O-N 2.66Å
259	G	98.6	Very high	98.2	Very high	0 Å²	0	3.6 Å²	3.6	0%	0	2%	0.021	C	C	.	.	H	α-helix	trans	-60.3	-41.9	-178.2	0	0	0	0	0	113.2	C180 C255 Y256 A263	C180-G259 VanDerWaalsContact CB-O 3.24Å; C180-G259 WeakPolarHBondContact CB-O 3.42Å; C255-G259 PolarHBondContact O-N 3.2Å; Y256-G259 PolarHBondContact O-N 3.49Å; G259-A263 WeakPolarHBondContact O-CB 3.31Å; G259-A263 PolarHBondContact O-N 3.16Å
260	M	98.7	Very high	98	Very high	0 Å²	0	5.8 Å²	5.8	0%	0	3%	0.031	C	C	.	.	H	α-helix	trans	-68.7	-41	176.3	-178.3	59.7	74.3	0	0	111.9	A104 I105 M108 A132 A177 Y256 A258 F262 A263 V264	A104-M260 HydrophobicContact CB-CG 4.44Å; A104-M260 HydrophobicContact CB-SD 4.11Å; I105-M260 HydrophobicContact CG1-CG 4.13Å; M108-M260 HydrophobicContact CB-CB 3.75Å; M108-M260 HydrophobicContact CB-CE 4.45Å; M108-M260 HydrophobicContact CB-CG 3.86Å; M108-M260 HydrophobicContact CE-CB 4.16Å; M108-M260 HydrophobicContact CE-CE 3.3Å; M108-M260 HydrophobicContact CG-CB 3.63Å; M108-M260 HydrophobicContact CG-CG 4.28Å; A132-M260 HydrophobicContact CB-CE 4.07Å; A177-M260 HydrophobicContact CB-CE 3.86Å; A177-M260 HydrophobicContact CB-SD 4.22Å; Y256-M260 WeakPolarHBondContact O-CB 3.49Å; Y256-M260 PolarHBondContact O-N 2.93Å; A258-M260 VanDerWaalsContact C-N 3.34Å; A258-M260 PolarHBondContact O-N 2.91Å; M260-F262 VanDerWaalsContact C-N 3.3Å; M260-F262 PolarHBondContact O-N 2.74Å; M260-A263 PolarHBondContact O-N 2.95Å; M260-V264 HydrophobicContact CG-CG2 4.18Å; M260-V264 WeakPolarHBondContact O-CB 3.4Å; M260-V264 WeakPolarHBondContact O-CG2 3.24Å; M260-V264 PolarHBondContact O-N 3.4Å; M260-V264 HydrophobicContact SD-CG2 3.98Å
261	T	98.9	Very high	97.8	Very high	0 Å²	0	6 Å²	6	0%	0	3%	0.031	C	C	.	.	H	α-helix	trans	-60.9	-41.7	177.7	-52.5	0	0	0	0	111.1	F66 I105 F227 M228 F231 F257 A258 V265	F66-T261 HydrophobicContact CZ-CG2 4.13Å; I105-T261 HydrophobicContact CD1-CG2 4.06Å; F227-T261 HydrophobicContact CB-CG2 4.43Å; M228-T261 HydrophobicContact CE-CG2 3.48Å; M228-T261 VanDerWaalsContact CE-CG2 3.48Å; F231-T261 HydrophobicContact CB-CG2 4.26Å; F231-T261 HydrophobicContact CD2-CG2 3.94Å; F231-T261 HydrophobicContact CG-CG2 4.19Å; F257-T261 WeakPolarHBondContact CD2-OG1 3.5Å; F257-T261 VanDerWaalsContact CE2-OG1 3.31Å; F257-T261 WeakPolarHBondContact CE2-OG1 3.29Å; F257-T261 WeakPolarHBondContact O-CB 3.3Å; F257-T261 PolarHBondContact O-N 2.71Å; F257-T261 PolarHBondContact O-OG1 2.99Å; A258-T261 PolarHBondContact O-N 2.98Å; T261-V265 PolarHBondContact O-N 3.21Å
262	F	98.9	Very high	97.7	Very high	0 Å²	0	6 Å²	6	0%	0	3%	0.03	C	C	.	.	H	α-helix	trans	-63.8	-50.5	173.4	-65.3	-48.5	0	0	0	112.1	I184 S198 I201 I205 M228 F231 A258 M260 V264 V265 G266 M275 F279	I184-F262 HydrophobicContact CD1-CD2 4.04Å; I184-F262 HydrophobicContact CD1-CE2 4Å; S198-F262 WeakPolarHBondContact O-CZ 3.01Å; I201-F262 HydrophobicContact CB-CE1 4.24Å; I201-F262 HydrophobicContact CB-CE2 4.35Å; I201-F262 HydrophobicContact CB-CZ 3.88Å; I201-F262 HydrophobicContact CG2-CD1 3.95Å; I201-F262 HydrophobicContact CG2-CD2 4.38Å; I201-F262 HydrophobicContact CG2-CE1 3.61Å; I201-F262 HydrophobicContact CG2-CE2 4.04Å; I201-F262 HydrophobicContact CG2-CG 4.33Å; I201-F262 HydrophobicContact CG2-CZ 3.65Å; I205-F262 HydrophobicContact CD1-CD1 3.62Å; I205-F262 HydrophobicContact CD1-CE1 4Å; M228-F262 HydrophobicContact CE-CD1 4.02Å; M228-F262 HydrophobicContact CE-CE1 4.23Å; M228-F262 HydrophobicContact SD-CD1 4Å; M228-F262 HydrophobicContact SD-CE1 3.93Å; F231-F262 HydrophobicContact CD1-CE1 4.38Å; F231-F262 HydrophobicContact CD1-CZ 4.35Å; F231-F262 AromaticContact CE1-CE1 3.99Å; F231-F262 HydrophobicContact CE1-CE1 3.99Å; F231-F262 HydrophobicContact CE1-CE2 4.27Å; F231-F262 AromaticContact CE1-CZ 3.53Å; F231-F262 HydrophobicContact CE1-CZ 3.53Å; F231-F262 HydrophobicContact CZ-CE2 4.23Å; F231-F262 AromaticContact CZ-CZ 3.95Å; F231-F262 HydrophobicContact CZ-CZ 3.95Å; A258-F262 HydrophobicContact CB-CE2 4.13Å; A258-F262 WeakPolarHBondContact O-CD2 3.19Å; A258-F262 WeakPolarHBondContact O-CG 3.45Å; A258-F262 PolarHBondContact O-N 2.66Å; M260-F262 VanDerWaalsContact C-N 3.3Å; M260-F262 PolarHBondContact O-N 2.74Å; F262-V264 VanDerWaalsContact C-N 3.27Å; F262-V264 PolarHBondContact O-N 3.19Å; F262-V265 VanDerWaalsContact O-CG2 3.31Å; F262-V265 WeakPolarHBondContact O-CG2 3.24Å; F262-V265 PolarHBondContact O-N 2.79Å; F262-G266 PolarHBondContact O-N 2.74Å; F262-M275 HydrophobicContact CB-SD 3.91Å; F262-F279 HydrophobicContact CB-CE2 4.07Å; F262-F279 HydrophobicContact CB-CZ 3.97Å; F262-F279 AromaticContact CD2-CE2 3.98Å; F262-F279 HydrophobicContact CD2-CE2 3.98Å; F262-F279 AromaticContact CD2-CZ 3.54Å; F262-F279 HydrophobicContact CD2-CZ 3.54Å; F262-F279 HydrophobicContact CE2-CZ 4.28Å; F262-F279 HydrophobicContact CG-CE2 4.03Å; F262-F279 AromaticContact CG-CZ 3.95Å; F262-F279 HydrophobicContact CG-CZ 3.95Å
263	A	98.6	Very high	97.5	Very high	0 Å²	0	9.2 Å²	9.2	0%	0	4%	0.043	C	C	.	.	H	α-helix	trans	-56.9	-41.4	178.9	0	0	0	0	0	112.2	A177 G259 M260 G266 I267	A177-A263 HydrophobicContact CB-CB 4.05Å; G259-A263 WeakPolarHBondContact O-CB 3.31Å; G259-A263 PolarHBondContact O-N 3.16Å; M260-A263 PolarHBondContact O-N 2.95Å; A263-G266 PolarHBondContact O-N 3.37Å; A263-I267 VanDerWaalsContact O-CB 3.25Å; A263-I267 WeakPolarHBondContact O-CB 3.41Å; A263-I267 WeakPolarHBondContact O-CD1 2.92Å; A263-I267 WeakPolarHBondContact O-CG1 3Å; A263-I267 PolarHBondContact O-N 2.97Å
264	V	98.6	Very high	97.4	Very high	0 Å²	0	9.8 Å²	9.8	0%	0	5%	0.047	C	C	.	.	H	α-helix	trans	-58.3	-54.2	176.5	163.2	0	0	0	0	111.6	A101 A104 I105 L136 M260 F262 G266 I267 L268	A101-V264 HydrophobicContact CB-CG1 3.41Å; A101-V264 VanDerWaalsContact CB-CG1 3.41Å; A104-V264 HydrophobicContact CB-CG2 4.28Å; I105-V264 HydrophobicContact CD1-CB 4.44Å; I105-V264 HydrophobicContact CD1-CG1 4.3Å; I105-V264 HydrophobicContact CD1-CG2 4.35Å; I105-V264 HydrophobicContact CG1-CG2 4.05Å; L136-V264 HydrophobicContact CD1-CB 4.31Å; L136-V264 HydrophobicContact CD1-CG1 4.35Å; L136-V264 HydrophobicContact CD1-CG2 3.98Å; L136-V264 HydrophobicContact CD2-CG2 4.13Å; M260-V264 HydrophobicContact CG-CG2 4.18Å; M260-V264 WeakPolarHBondContact O-CB 3.4Å; M260-V264 WeakPolarHBondContact O-CG2 3.24Å; M260-V264 PolarHBondContact O-N 3.4Å; M260-V264 HydrophobicContact SD-CG2 3.98Å; F262-V264 VanDerWaalsContact C-N 3.27Å; F262-V264 PolarHBondContact O-N 3.19Å; V264-G266 VanDerWaalsContact C-N 3.34Å; V264-G266 PolarHBondContact O-N 3.39Å; V264-I267 PolarHBondContact O-N 2.96Å; V264-L268 HydrophobicContact CG1-CD1 4.37Å; V264-L268 PolarHBondContact O-N 3.41Å
265	V	98.6	Very high	97.3	Very high	0 Å²	0	9.8 Å²	9.8	0%	0	5%	0.047	C	C	.	.	H	α-helix	trans	-69.6	-33.9	-178	-59.9	0	0	0	0	111.9	F227 M228 T261 F262 G269 F271	F227-V265 HydrophobicContact CB-CG1 3.7Å; F227-V265 HydrophobicContact CD2-CG1 4.35Å; F227-V265 HydrophobicContact CG-CG1 4.22Å; M228-V265 HydrophobicContact CE-CB 4.41Å; M228-V265 HydrophobicContact CE-CG1 3.82Å; M228-V265 HydrophobicContact CE-CG2 3.7Å; M228-V265 HydrophobicContact CG-CG1 4.36Å; M228-V265 HydrophobicContact CG-CG2 4.28Å; M228-V265 HydrophobicContact SD-CG2 4.02Å; T261-V265 PolarHBondContact O-N 3.21Å; F262-V265 VanDerWaalsContact O-CG2 3.31Å; F262-V265 WeakPolarHBondContact O-CG2 3.24Å; F262-V265 PolarHBondContact O-N 2.79Å; V265-G269 VanDerWaalsContact O-CA 3.25Å; V265-G269 WeakPolarHBondContact O-CA 3.49Å; V265-G269 PolarHBondContact O-N 3.32Å; V265-F271 HydrophobicContact CB-CZ 4.06Å; V265-F271 HydrophobicContact CG2-CE2 4.26Å; V265-F271 HydrophobicContact CG2-CZ 4.17Å; V265-F271 WeakPolarHBondContact O-CE1 3.5Å; V265-F271 WeakPolarHBondContact O-CZ 3.41Å
266	G	97.9	Very high	97.3	Very high	0 Å²	0	11.9 Å²	11.9	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-67.8	-37	176.3	0	0	0	0	0	113.2	F262 A263 V264 H270 F271 S272	F262-G266 PolarHBondContact O-N 2.74Å; A263-G266 PolarHBondContact O-N 3.37Å; V264-G266 VanDerWaalsContact C-N 3.34Å; V264-G266 PolarHBondContact O-N 3.39Å; G266-H270 PolarHBondContact O-N 3.25Å; G266-F271 PolarHBondContact O-N 3.31Å; G266-F271 VanDerWaalsContact O-N 3.15Å; G266-S272 WeakPolarHBondContact O-CA 3.48Å; G266-S272 WeakPolarHBondContact O-CB 3.46Å; G266-S272 PolarHBondContact O-N 3.27Å
267	I	97.3	Very high	97.2	Very high	2 Å²	2	14.7 Å²	14.7	1%	0.01	7%	0.072	C	C	.	.	H	α-helix	trans	-77.4	-54.8	-179.8	-73.1	165.7	0	0	0	110.9	L136 Y140 M173 L176 A263 V264 G269 H270	L136-I267 HydrophobicContact CD1-CG2 4.36Å; L136-I267 HydrophobicContact CD2-CB 4.04Å; L136-I267 HydrophobicContact CD2-CD1 3.38Å; L136-I267 HydrophobicContact CD2-CG1 4.27Å; L136-I267 HydrophobicContact CD2-CG2 4.16Å; L136-I267 HydrophobicContact CG-CB 4.41Å; L136-I267 HydrophobicContact CG-CD1 4.37Å; L136-I267 HydrophobicContact CG-CG2 4.05Å; Y140-I267 HydrophobicContact CD2-CG2 3.88Å; Y140-I267 HydrophobicContact CE2-CG2 4.39Å; M173-I267 HydrophobicContact CB-CD1 3.77Å; M173-I267 HydrophobicContact CB-CG1 4.43Å; M173-I267 HydrophobicContact CG-CD1 4Å; M173-I267 HydrophobicContact CG-CG1 4.1Å; M173-I267 HydrophobicContact CG-CG2 4.15Å; M173-I267 HydrophobicContact SD-CG1 4.5Å; M173-I267 HydrophobicContact SD-CG2 3.44Å; M173-I267 WeakPolarHBondContact SD-CG2 3.46Å; L176-I267 HydrophobicContact CD2-CD1 4Å; L176-I267 HydrophobicContact CD2-CG1 3.83Å; A263-I267 VanDerWaalsContact O-CB 3.25Å; A263-I267 WeakPolarHBondContact O-CB 3.41Å; A263-I267 WeakPolarHBondContact O-CD1 2.92Å; A263-I267 WeakPolarHBondContact O-CG1 3Å; A263-I267 PolarHBondContact O-N 2.97Å; V264-I267 PolarHBondContact O-N 2.96Å; I267-G269 VanDerWaalsContact C-N 3.34Å; I267-H270 PolarHBondContact O-N 3.37Å
268	L	96.2	Very high	97.2	Very high	3 Å²	3	14.7 Å²	14.7	2%	0.016	7%	0.072	C	C	.	.	H	α-helix	trans	-77.1	-22.4	-176.6	-62	179.3	0	0	0	113	A97 A101 L136 V139 F144 F223 V264 H270	A97-L268 HydrophobicContact CB-CD1 4.43Å; A101-L268 HydrophobicContact CB-CD1 4.06Å; L136-L268 HydrophobicContact CD1-CD1 3.57Å; L136-L268 HydrophobicContact CD1-CD2 3.87Å; L136-L268 HydrophobicContact CD1-CG 3.47Å; L136-L268 VanDerWaalsContact CD1-CG 3.47Å; V139-L268 HydrophobicContact CB-CD2 4.44Å; V139-L268 HydrophobicContact CG1-CD1 4.29Å; V139-L268 HydrophobicContact CG1-CD2 3.72Å; F144-L268 HydrophobicContact CE2-CD2 4.04Å; F223-L268 HydrophobicContact CD1-CB 4.27Å; F223-L268 HydrophobicContact CE1-CB 3.62Å; F223-L268 HydrophobicContact CE1-CD1 3.88Å; F223-L268 HydrophobicContact CE1-CG 4.39Å; F223-L268 HydrophobicContact CZ-CB 4.13Å; F223-L268 HydrophobicContact CZ-CD1 3.58Å; V264-L268 HydrophobicContact CG1-CD1 4.37Å; V264-L268 PolarHBondContact O-N 3.41Å; L268-H270 VanDerWaalsContact C-N 3.32Å; L268-H270 PolarHBondContact O-CD2 3.2Å
269	G	95.1	Very high	97.2	Very high	2 Å²	2	14.7 Å²	14.7	2%	0.021	7%	0.072	C	C	.	.	T	Hydrogen-bonded Turn	trans	-89	5.3	170.8	0	0	0	0	0	113.7	V265 I267 F271	V265-G269 VanDerWaalsContact O-CA 3.25Å; V265-G269 WeakPolarHBondContact O-CA 3.49Å; V265-G269 PolarHBondContact O-N 3.32Å; I267-G269 VanDerWaalsContact C-N 3.34Å; G269-F271 WeakPolarHBondContact O-CD1 3.21Å; G269-F271 PolarHBondContact O-N 3.25Å
270	H	94.8	Very high	97.2	Very high	72 Å²	72	17.9 Å²	17.9	33%	0.333	9%	0.088	S	C	.	.	T	Hydrogen-bonded Turn	trans	57.2	17.3	176.5	-62.4	-79.7	0	0	0	116.8	Y140 F144 D220 G266 I267 L268	Y140-H270 AromaticContact CE2-CE1 3.49Å; Y140-H270 VanDerWaalsContact CE2-CE1 3.49Å; Y140-H270 WeakPolarHBondContact CE2-CE1 3.23Å; Y140-H270 AromaticContact CZ-CE1 3.91Å; F144-H270 AromaticContact CD1-CE1 3.95Å; F144-H270 AromaticContact CD1-NE2 3.22Å; F144-H270 WeakPolarHBondContact CD1-NE2 3.42Å; F144-H270 AromaticContact CE1-NE2 3.48Å; F144-H270 WeakPolarHBondContact CE1-NE2 3.46Å; F144-H270 AromaticContact CG-CE1 3.88Å; F144-H270 AromaticContact CG-NE2 3.51Å; F144-H270 AromaticContact CZ-NE2 3.98Å; D220-H270 IonicContact OD2-CD2 3.64Å; G266-H270 PolarHBondContact O-N 3.25Å; I267-H270 PolarHBondContact O-N 3.37Å; L268-H270 VanDerWaalsContact C-N 3.32Å; L268-H270 PolarHBondContact O-CD2 3.2Å
271	F	95.5	Very high	97.2	Very high	11 Å²	11	18.3 Å²	18.3	5%	0.048	9%	0.091	C	C	.	.			trans	-114	24.1	179	57.2	-105.2	0	0	0	113.8	I205 F208 H221 S224 V265 G266 G269 K273 T274 M275	I205-F271 HydrophobicContact CG2-CE2 4.12Å; I205-F271 HydrophobicContact CG2-CZ 4.3Å; F208-F271 HydrophobicContact CD1-CD2 4.5Å; F208-F271 HydrophobicContact CD1-CG 4.43Å; F208-F271 HydrophobicContact CE1-CB 3.69Å; F208-F271 AromaticContact CE1-CD1 3.95Å; F208-F271 HydrophobicContact CE1-CD1 3.95Å; F208-F271 HydrophobicContact CE1-CD2 4.06Å; F208-F271 AromaticContact CE1-CG 3.63Å; F208-F271 HydrophobicContact CE1-CG 3.63Å; F208-F271 HydrophobicContact CZ-CB 4.15Å; H221-F271 AromaticContact CE1-CD1 3.7Å; H221-F271 AromaticContact ND1-CD1 3.98Å; S224-F271 WeakPolarHBondContact OG-CZ 3.46Å; V265-F271 HydrophobicContact CB-CZ 4.06Å; V265-F271 HydrophobicContact CG2-CE2 4.26Å; V265-F271 HydrophobicContact CG2-CZ 4.17Å; V265-F271 WeakPolarHBondContact O-CE1 3.5Å; V265-F271 WeakPolarHBondContact O-CZ 3.41Å; G266-F271 PolarHBondContact O-N 3.31Å; G266-F271 VanDerWaalsContact O-N 3.15Å; G269-F271 WeakPolarHBondContact O-CD1 3.21Å; G269-F271 PolarHBondContact O-N 3.25Å; F271-K273 PolarHBondContact O-N 3.01Å; F271-T274 WeakPolarHBondContact O-CB 3.27Å; F271-T274 PolarHBondContact O-N 3Å; F271-M275 HydrophobicContact CD2-CB 4.35Å; F271-M275 PolarHBondContact O-N 2.84Å
272	S	95.4	Very high	97.2	Very high	7 Å²	7	18.3 Å²	18.3	5%	0.049	9%	0.091	C	C	.	.	H	α-helix	trans	-51.1	-33	179.1	61.2	0	0	0	0	114.1	Y172 G266 M275 L276	Y172-S272 WeakPolarHBondContact OH-CB 3.34Å; Y172-S272 PolarHBondContact OH-OG 3.12Å; Y172-S272 VanDerWaalsContact OH-OG 3.14Å; G266-S272 WeakPolarHBondContact O-CA 3.48Å; G266-S272 WeakPolarHBondContact O-CB 3.46Å; G266-S272 PolarHBondContact O-N 3.27Å; S272-M275 PolarHBondContact O-N 2.95Å; S272-L276 WeakPolarHBondContact O-CB 3.24Å; S272-L276 WeakPolarHBondContact O-CG 3.41Å; S272-L276 PolarHBondContact O-N 2.78Å
273	K	93.1	Very high	97.2	Very high	94 Å²	94	20.5 Å²	20.5	41%	0.409	10%	0.104	S	C	.	.	H	α-helix	trans	-63.6	-49.2	173.6	-62.1	-180	-174.6	177.3	0	112	V150 F271 M275 L276 L277 Y406	V150-K273 PolarHBondContact O-NZ 2.91Å; V150-K273 VanDerWaalsContact O-NZ 3.14Å; F271-K273 PolarHBondContact O-N 3.01Å; K273-M275 VanDerWaalsContact C-N 3.33Å; K273-L276 PolarHBondContact O-N 3.43Å; K273-L277 PolarHBondContact O-N 3.04Å; K273-Y406 PolarHBondContact NZ-OH 3.19Å
274	T	95.4	Very high	97.2	Very high	13 Å²	13	24.5 Å²	24.5	8%	0.08	12%	0.121	C	C	.	.	H	α-helix	trans	-64.7	-40.6	176.5	-51.8	0	0	0	0	110.6	F208 F271 L276 L277 F278 T394	F208-T274 HydrophobicContact CD1-CG2 4.5Å; F208-T274 HydrophobicContact CD2-CG2 4.28Å; F208-T274 HydrophobicContact CE1-CG2 4.27Å; F208-T274 HydrophobicContact CE2-CG2 4.07Å; F208-T274 HydrophobicContact CZ-CG2 4.07Å; F271-T274 WeakPolarHBondContact O-CB 3.27Å; F271-T274 PolarHBondContact O-N 3Å; T274-L276 PolarHBondContact O-N 2.92Å; T274-L277 WeakPolarHBondContact O-CB 3.44Å; T274-L277 PolarHBondContact O-N 3.37Å; T274-L277 VanDerWaalsContact O-N 3.13Å; T274-F278 HydrophobicContact CG2-CE2 3.87Å; T274-F278 HydrophobicContact CG2-CZ 4.23Å; T274-F278 PolarHBondContact O-N 2.97Å; T274-F278 VanDerWaalsContact O-N 3.14Å; T274-T394 HydrophobicContact CG2-CG2 4.24Å
275	M	97.9	Very high	97.2	Very high	0 Å²	0	24.6 Å²	24.6	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-59	-44.9	175.1	-173.9	-162.1	76.8	0	0	112	L176 I205 F262 F271 S272 K273 L277 F278 F279	L176-M275 HydrophobicContact CD1-CE 3.8Å; L176-M275 HydrophobicContact CD2-CE 4Å; L176-M275 HydrophobicContact CG-CE 4.1Å; I205-M275 HydrophobicContact CD1-CG 4.15Å; F262-M275 HydrophobicContact CB-SD 3.91Å; F271-M275 HydrophobicContact CD2-CB 4.35Å; F271-M275 PolarHBondContact O-N 2.84Å; S272-M275 PolarHBondContact O-N 2.95Å; K273-M275 VanDerWaalsContact C-N 3.33Å; M275-L277 PolarHBondContact O-N 2.89Å; M275-F278 WeakPolarHBondContact O-CA 3.5Å; M275-F278 WeakPolarHBondContact O-CB 3.45Å; M275-F278 PolarHBondContact O-N 3.14Å; M275-F279 HydrophobicContact CG-CD2 4.34Å; M275-F279 HydrophobicContact CG-CE2 4.19Å; M275-F279 WeakPolarHBondContact O-CD2 3.35Å; M275-F279 PolarHBondContact O-N 2.89Å; M275-F279 VanDerWaalsContact O-N 3.11Å
276	L	97.7	Very high	97.2	Very high	46 Å²	46	27.6 Å²	27.6	24%	0.241	14%	0.135	C	C	.	.	H	α-helix	trans	-62.8	-29	176.9	-79.9	173.6	0	0	0	113.1	Y172 L176 F179 S272 K273 T274 F279	Y172-L276 HydrophobicContact CE2-CD1 4.48Å; L176-L276 HydrophobicContact CD1-CD1 4.04Å; L176-L276 HydrophobicContact CD1-CD2 3.65Å; L176-L276 HydrophobicContact CD1-CG 3.9Å; F179-L276 HydrophobicContact CD1-CD2 3.98Å; F179-L276 HydrophobicContact CE1-CD2 3.8Å; S272-L276 WeakPolarHBondContact O-CB 3.24Å; S272-L276 WeakPolarHBondContact O-CG 3.41Å; S272-L276 PolarHBondContact O-N 2.78Å; K273-L276 PolarHBondContact O-N 3.43Å; T274-L276 PolarHBondContact O-N 2.92Å; L276-F279 WeakPolarHBondContact O-CB 3.37Å; L276-F279 PolarHBondContact O-N 2.91Å; L276-F279 VanDerWaalsContact O-N 3.15Å
277	L	97.4	Very high	97.3	Very high	59 Å²	59	32.5 Å²	32.5	31%	0.309	16%	0.161	S	C	.	.	H	α-helix	trans	-69.4	-37.5	171.8	-66	175.4	0	0	0	111.7	K273 T274 M275 F279 M280 T394 I397	K273-L277 PolarHBondContact O-N 3.04Å; T274-L277 WeakPolarHBondContact O-CB 3.44Å; T274-L277 PolarHBondContact O-N 3.37Å; T274-L277 VanDerWaalsContact O-N 3.13Å; M275-L277 PolarHBondContact O-N 2.89Å; L277-F279 PolarHBondContact O-N 3.05Å; L277-M280 VanDerWaalsContact O-CB 3.28Å; L277-M280 WeakPolarHBondContact O-CB 3.11Å; L277-M280 PolarHBondContact O-N 3.41Å; L277-M280 VanDerWaalsContact O-N 3.14Å; L277-T394 VanDerWaalsContact C-OG1 3.26Å; L277-T394 HydrophobicContact CB-CG2 3.43Å; L277-T394 VanDerWaalsContact CB-CG2 3.43Å; L277-T394 WeakPolarHBondContact CB-OG1 3.34Å; L277-T394 HydrophobicContact CD1-CG2 4.15Å; L277-T394 HydrophobicContact CG-CG2 4.45Å; L277-T394 PolarHBondContact O-OG1 3.4Å; L277-I397 HydrophobicContact CD1-CG2 4.24Å
278	F	98.6	Very high	97.3	Very high	0 Å²	0	33.4 Å²	33.4	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-63	-23.3	168.9	-64	-49	0	0	0	112.6	I205 F208 T274 M275 M280 Q387 T394 F395	I205-F278 HydrophobicContact CG1-CD2 3.91Å; I205-F278 HydrophobicContact CG1-CE2 4.25Å; F208-F278 HydrophobicContact CB-CE2 4.14Å; F208-F278 HydrophobicContact CB-CZ 4.14Å; F208-F278 HydrophobicContact CG-CE2 4.37Å; T274-F278 HydrophobicContact CG2-CE2 3.87Å; T274-F278 HydrophobicContact CG2-CZ 4.23Å; T274-F278 PolarHBondContact O-N 2.97Å; T274-F278 VanDerWaalsContact O-N 3.14Å; M275-F278 WeakPolarHBondContact O-CA 3.5Å; M275-F278 WeakPolarHBondContact O-CB 3.45Å; M275-F278 PolarHBondContact O-N 3.14Å; F278-M280 PolarHBondContact O-N 2.93Å; F278-Q387 PolarHBondContact O-NE2 3.24Å; F278-T394 HydrophobicContact CD1-CG2 3.67Å; F278-T394 HydrophobicContact CE1-CG2 3.47Å; F278-T394 VanDerWaalsContact CE1-CG2 3.47Å; F278-T394 HydrophobicContact CG-CG2 4.26Å; F278-T394 HydrophobicContact CZ-CG2 3.93Å; F278-F395 HydrophobicContact CE1-CD2 4.26Å; F278-F395 HydrophobicContact CE1-CE1 4.39Å; F278-F395 AromaticContact CE1-CE2 3.97Å; F278-F395 HydrophobicContact CE1-CE2 3.97Å; F278-F395 HydrophobicContact CE1-CZ 4.06Å; F278-F395 HydrophobicContact CZ-CD1 4.37Å; F278-F395 AromaticContact CZ-CE1 3.89Å; F278-F395 HydrophobicContact CZ-CE1 3.89Å; F278-F395 HydrophobicContact CZ-CE2 4.18Å; F278-F395 AromaticContact CZ-CZ 3.78Å; F278-F395 HydrophobicContact CZ-CZ 3.78Å
279	F	98.7	Very high	97.4	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	16%	0.163	C	C	.	.	T	Hydrogen-bonded Turn	trans	-83.7	16.8	174.6	-87.8	-115.5	0	0	0	114.1	F179 C180 I184 I201 F262 M275 L276 L277 Q282 V283	F179-F279 HydrophobicContact CE1-CD1 4.18Å; C180-F279 HydrophobicContact CB-CE1 4.02Å; C180-F279 HydrophobicContact CB-CZ 4.15Å; I184-F279 HydrophobicContact CD1-CE1 4.18Å; I184-F279 HydrophobicContact CD1-CZ 4.26Å; I184-F279 HydrophobicContact CG1-CE1 4.13Å; I201-F279 HydrophobicContact CD1-CD2 4.13Å; I201-F279 HydrophobicContact CD1-CE2 4.01Å; I201-F279 HydrophobicContact CD1-CG 4.49Å; I201-F279 HydrophobicContact CD1-CZ 4.23Å; I201-F279 HydrophobicContact CG2-CD2 4.16Å; I201-F279 HydrophobicContact CG2-CE2 3.68Å; F262-F279 HydrophobicContact CB-CE2 4.07Å; F262-F279 HydrophobicContact CB-CZ 3.97Å; F262-F279 AromaticContact CD2-CE2 3.98Å; F262-F279 HydrophobicContact CD2-CE2 3.98Å; F262-F279 AromaticContact CD2-CZ 3.54Å; F262-F279 HydrophobicContact CD2-CZ 3.54Å; F262-F279 HydrophobicContact CE2-CZ 4.28Å; F262-F279 HydrophobicContact CG-CE2 4.03Å; F262-F279 AromaticContact CG-CZ 3.95Å; F262-F279 HydrophobicContact CG-CZ 3.95Å; M275-F279 HydrophobicContact CG-CD2 4.34Å; M275-F279 HydrophobicContact CG-CE2 4.19Å; M275-F279 WeakPolarHBondContact O-CD2 3.35Å; M275-F279 PolarHBondContact O-N 2.89Å; M275-F279 VanDerWaalsContact O-N 3.11Å; L276-F279 WeakPolarHBondContact O-CB 3.37Å; L276-F279 PolarHBondContact O-N 2.91Å; L276-F279 VanDerWaalsContact O-N 3.15Å; L277-F279 PolarHBondContact O-N 3.05Å; F279-Q282 HydrophobicContact CB-CB 4.38Å; F279-Q282 HydrophobicContact CD1-CB 3.88Å; F279-Q282 HydrophobicContact CD1-CG 3.97Å; F279-Q282 WeakPolarHBondContact O-CA 3.43Å; F279-Q282 WeakPolarHBondContact O-CB 3.5Å; F279-Q282 PolarHBondContact O-N 3.08Å; F279-Q282 PolarHBondContact O-OE1 3.3Å; F279-Q282 VanDerWaalsContact O-OE1 3.12Å; F279-V283 HydrophobicContact CB-CG2 4.31Å; F279-V283 WeakPolarHBondContact O-CG2 3.19Å; F279-V283 PolarHBondContact O-N 3.49Å
280	M	98.5	Very high	97.6	Very high	66 Å²	66	35.9 Å²	35.9	33%	0.325	18%	0.177	S	C	.	.	H	α-helix	trans	-53.9	-46.4	-172.7	-177.4	174	-59.6	0	0	114.5	L277 F278 Q282 V283 F284 F393	L277-M280 VanDerWaalsContact O-CB 3.28Å; L277-M280 WeakPolarHBondContact O-CB 3.11Å; L277-M280 PolarHBondContact O-N 3.41Å; L277-M280 VanDerWaalsContact O-N 3.14Å; F278-M280 PolarHBondContact O-N 2.93Å; M280-Q282 VanDerWaalsContact C-N 3.34Å; M280-Q282 PolarHBondContact O-N 2.9Å; M280-V283 PolarHBondContact O-N 3.4Å; M280-F284 WeakPolarHBondContact O-CB 3.39Å; M280-F284 PolarHBondContact O-N 2.64Å; M280-F393 HydrophobicContact CE-CD1 3.65Å; M280-F393 HydrophobicContact CE-CE1 3.89Å; M280-F393 HydrophobicContact SD-CD1 4.08Å; M280-F393 HydrophobicContact SD-CE1 4.47Å
281	P	98.7	Very high	97.7	Very high	10 Å²	10	33.5 Å²	33.5	7%	0.065	17%	0.167	C	C	.	.	H	α-helix	trans	-63.5	-36.9	175.1	-25.7	38.7	0	0	0	113.5	L187 F284 N285 L363 Q387	L187-P281 HydrophobicContact CD2-CB 4.39Å; P281-F284 PolarHBondContact O-N 2.86Å; P281-N285 WeakPolarHBondContact O-CB 3.25Å; P281-N285 PolarHBondContact O-N 2.84Å; P281-L363 HydrophobicContact CB-CD2 3.96Å; P281-Q387 HydrophobicContact CG-CB 4.47Å; P281-Q387 VanDerWaalsContact CG-OE1 3.23Å
282	Q	98.9	Very high	97.9	Very high	0 Å²	0	33 Å²	33	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-67.6	-44.9	178.2	-65.7	71.8	21.5	0	0	110.9	A183 L187 F279 M280 N285 F286	A183-Q282 HydrophobicContact CB-CB 3.97Å; L187-Q282 HydrophobicContact CD2-CG 4.23Å; F279-Q282 HydrophobicContact CB-CB 4.38Å; F279-Q282 HydrophobicContact CD1-CB 3.88Å; F279-Q282 HydrophobicContact CD1-CG 3.97Å; F279-Q282 WeakPolarHBondContact O-CA 3.43Å; F279-Q282 WeakPolarHBondContact O-CB 3.5Å; F279-Q282 PolarHBondContact O-N 3.08Å; F279-Q282 PolarHBondContact O-OE1 3.3Å; F279-Q282 VanDerWaalsContact O-OE1 3.12Å; M280-Q282 VanDerWaalsContact C-N 3.34Å; M280-Q282 PolarHBondContact O-N 2.9Å; Q282-N285 PolarHBondContact O-N 3.16Å; Q282-F286 VanDerWaalsContact O-CB 3.3Å; Q282-F286 WeakPolarHBondContact O-CB 3.49Å; Q282-F286 PolarHBondContact O-N 3.41Å
283	V	98.7	Very high	97.9	Very high	45 Å²	45	35.4 Å²	35.4	27%	0.273	18%	0.177	S	C	.	.	H	α-helix	trans	-59.1	-48.6	174.5	172.5	0	0	0	0	110.1	F179 F279 M280 F286 L287	F179-V283 HydrophobicContact CE1-CG2 4Å; F179-V283 HydrophobicContact CZ-CB 4.33Å; F179-V283 HydrophobicContact CZ-CG2 3.53Å; F279-V283 HydrophobicContact CB-CG2 4.31Å; F279-V283 WeakPolarHBondContact O-CG2 3.19Å; F279-V283 PolarHBondContact O-N 3.49Å; M280-V283 PolarHBondContact O-N 3.4Å; V283-F286 PolarHBondContact O-N 2.85Å; V283-L287 HydrophobicContact CG1-CD1 3.98Å; V283-L287 HydrophobicContact CG1-CG 4.47Å; V283-L287 WeakPolarHBondContact O-CG 3.21Å; V283-L287 PolarHBondContact O-N 3.02Å
284	F	98.7	Very high	98.1	Very high	85 Å²	85	36 Å²	36	37%	0.373	18%	0.184	S	C	.	.	H	α-helix	trans	-60.7	-48.2	177.8	179.1	-89.7	0	0	0	111.7	M280 P281 F286 L287 Y288 L363 L366	M280-F284 WeakPolarHBondContact O-CB 3.39Å; M280-F284 PolarHBondContact O-N 2.64Å; P281-F284 PolarHBondContact O-N 2.86Å; F284-F286 VanDerWaalsContact C-N 3.31Å; F284-F286 PolarHBondContact O-N 3.3Å; F284-L287 PolarHBondContact O-N 3.1Å; F284-Y288 VanDerWaalsContact O-CB 3.25Å; F284-Y288 WeakPolarHBondContact O-CB 3.27Å; F284-Y288 PolarHBondContact O-N 3.47Å; F284-L363 HydrophobicContact CD1-CB 4.48Å; F284-L363 HydrophobicContact CD1-CD1 3.84Å; F284-L363 HydrophobicContact CE1-CD1 3.85Å; F284-L366 HydrophobicContact CE1-CD2 3.55Å; F284-L366 HydrophobicContact CZ-CD2 3.57Å
285	N	98.8	Very high	98.2	Very high	1 Å²	1	41.9 Å²	41.9	1%	0.005	21%	0.211	C	C	.	.	H	α-helix	trans	-60.6	-40.2	178.4	-178.7	65.8	0	0	0	112.2	I186 L187 P281 Q282 S289 T362 L363	I186-N285 PolarHBondContact O-ND2 3.46Å; L187-N285 HydrophobicContact CB-CB 4.48Å; L187-N285 HydrophobicContact CD1-CB 4.16Å; L187-N285 HydrophobicContact CD2-CB 4.28Å; P281-N285 WeakPolarHBondContact O-CB 3.25Å; P281-N285 PolarHBondContact O-N 2.84Å; Q282-N285 PolarHBondContact O-N 3.16Å; N285-S289 WeakPolarHBondContact O-CB 3.32Å; N285-S289 PolarHBondContact O-N 3.45Å; N285-S289 PolarHBondContact O-OG 2.98Å; N285-T362 WeakPolarHBondContact OD1-CA 3.2Å; N285-L363 HydrophobicContact CB-CB 3.93Å; N285-L363 PolarHBondContact OD1-N 3.43Å
286	F	98.6	Very high	98.1	Very high	63 Å²	63	43.9 Å²	43.9	28%	0.276	22%	0.221	S	C	.	.	H	α-helix	trans	-62.8	-51.3	177	177.4	-94.3	0	0	0	111.7	F179 I186 Q282 V283 F284 Y288 S289 L290 L293	F179-F286 HydrophobicContact CD2-CG 4.47Å; F179-F286 HydrophobicContact CE2-CB 4.08Å; F179-F286 HydrophobicContact CE2-CD1 4.05Å; F179-F286 HydrophobicContact CE2-CD2 4.35Å; F179-F286 AromaticContact CE2-CG 3.9Å; F179-F286 HydrophobicContact CE2-CG 3.9Å; I186-F286 HydrophobicContact CD1-CB 4.06Å; I186-F286 HydrophobicContact CD1-CD2 3.75Å; I186-F286 HydrophobicContact CD1-CG 4.38Å; Q282-F286 VanDerWaalsContact O-CB 3.3Å; Q282-F286 WeakPolarHBondContact O-CB 3.49Å; Q282-F286 PolarHBondContact O-N 3.41Å; V283-F286 PolarHBondContact O-N 2.85Å; F284-F286 VanDerWaalsContact C-N 3.31Å; F284-F286 PolarHBondContact O-N 3.3Å; F286-Y288 PolarHBondContact O-N 3.41Å; F286-S289 PolarHBondContact O-N 3Å; F286-L290 HydrophobicContact CE1-CD1 4.28Å; F286-L290 HydrophobicContact CZ-CD1 4.23Å; F286-L290 PolarHBondContact O-N 2.95Å; F286-L293 HydrophobicContact CD2-CD1 4.28Å; F286-L293 HydrophobicContact CE2-CD1 4.3Å
287	L	98.5	Very high	98.1	Very high	104 Å²	104	41.7 Å²	41.7	55%	0.545	21%	0.21	S	C	.	.	H	α-helix	trans	-63.8	-42.5	179.3	-67.3	175.9	0	0	0	111.8	V283 F284 S289 L290	V283-L287 HydrophobicContact CG1-CD1 3.98Å; V283-L287 HydrophobicContact CG1-CG 4.47Å; V283-L287 WeakPolarHBondContact O-CG 3.21Å; V283-L287 PolarHBondContact O-N 3.02Å; F284-L287 PolarHBondContact O-N 3.1Å; L287-S289 VanDerWaalsContact C-N 3.32Å; L287-S289 PolarHBondContact O-N 3.47Å; L287-L290 VanDerWaalsContact O-CB 3.23Å; L287-L290 WeakPolarHBondContact O-CB 3.42Å; L287-L290 PolarHBondContact O-N 2.96Å
288	Y	98.6	Very high	98.1	Very high	20 Å²	20	41.1 Å²	41.1	8%	0.078	21%	0.209	C	C	.	.	H	α-helix	trans	-65.2	-36.2	176.5	-178.4	-128.4	0	0	0	112.1	F284 F286 L290 P291 L342 V343 N359 M361 T362 L366	F284-Y288 VanDerWaalsContact O-CB 3.25Å; F284-Y288 WeakPolarHBondContact O-CB 3.27Å; F284-Y288 PolarHBondContact O-N 3.47Å; F286-Y288 PolarHBondContact O-N 3.41Å; Y288-L290 VanDerWaalsContact C-N 3.3Å; Y288-L290 PolarHBondContact O-N 3.36Å; Y288-P291 WeakPolarHBondContact O-CD 3.33Å; Y288-L342 HydrophobicContact CE2-CB 4.05Å; Y288-L342 PolarHBondContact OH-O 3.32Å; Y288-V343 HydrophobicContact CE2-CG2 4.33Å; Y288-N359 PolarHBondContact OH-OD1 2.95Å; Y288-M361 HydrophobicContact CD1-CB 4.23Å; Y288-M361 HydrophobicContact CD2-CB 4.41Å; Y288-M361 VanDerWaalsContact CE1-CA 3.44Å; Y288-M361 HydrophobicContact CE1-CB 3.98Å; Y288-M361 HydrophobicContact CE2-CB 4.15Å; Y288-M361 HydrophobicContact CE2-CG 4.19Å; Y288-M361 HydrophobicContact CG-CB 4.44Å; Y288-M361 WeakPolarHBondContact O-CB 3.41Å; Y288-T362 VanDerWaalsContact CE1-N 3.28Å; Y288-T362 WeakPolarHBondContact CE1-O 3.5Å; Y288-L366 HydrophobicContact CE1-CB 4.09Å
289	S	98.5	Very high	98.1	Very high	0 Å²	0	42.9 Å²	42.9	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-73.6	-16.8	175.7	-69.7	0	0	0	0	114.1	N285 F286 L287 P291 Q292 L293 R303 M361	N285-S289 WeakPolarHBondContact O-CB 3.32Å; N285-S289 PolarHBondContact O-N 3.45Å; N285-S289 PolarHBondContact O-OG 2.98Å; F286-S289 PolarHBondContact O-N 3Å; L287-S289 VanDerWaalsContact C-N 3.32Å; L287-S289 PolarHBondContact O-N 3.47Å; S289-P291 VanDerWaalsContact C-CD 3.45Å; S289-Q292 PolarHBondContact O-N 3.31Å; S289-L293 WeakPolarHBondContact O-CG 3.5Å; S289-L293 PolarHBondContact O-N 3.49Å; S289-R303 VanDerWaalsContact CB-NH1 3.3Å; S289-R303 PolarHBondContact OG-NH1 3.25Å; S289-R303 PolarHBondContact OG-NH2 3.37Å; S289-R303 VanDerWaalsContact OG-NH2 3.17Å; S289-M361 VanDerWaalsContact CA-O 3.31Å; S289-M361 WeakPolarHBondContact CA-O 3.33Å; S289-M361 PolarHBondContact OG-O 3.05Å
290	L	98.1	Very high	97.9	Very high	58 Å²	58	44.9 Å²	44.9	30%	0.304	23%	0.234	S	C	.	.	H	α-helix	trans	-56.2	-40.7	-167	-166.4	64.8	0	0	0	114.3	F286 L287 Y288 Q292 L293 L294	F286-L290 HydrophobicContact CE1-CD1 4.28Å; F286-L290 HydrophobicContact CZ-CD1 4.23Å; F286-L290 PolarHBondContact O-N 2.95Å; L287-L290 VanDerWaalsContact O-CB 3.23Å; L287-L290 WeakPolarHBondContact O-CB 3.42Å; L287-L290 PolarHBondContact O-N 2.96Å; Y288-L290 VanDerWaalsContact C-N 3.3Å; Y288-L290 PolarHBondContact O-N 3.36Å; L290-Q292 PolarHBondContact O-N 3.27Å; L290-L293 PolarHBondContact O-N 2.85Å; L290-L294 HydrophobicContact CD1-CD1 3.99Å; L290-L294 HydrophobicContact CD1-CD2 4.48Å; L290-L294 HydrophobicContact CD1-CG 3.96Å; L290-L294 HydrophobicContact CD2-CD1 4.36Å; L290-L294 HydrophobicContact CG-CD1 3.79Å; L290-L294 HydrophobicContact CG-CG 4.15Å; L290-L294 WeakPolarHBondContact O-CB 3.35Å; L290-L294 WeakPolarHBondContact O-CG 3.47Å; L290-L294 PolarHBondContact O-N 2.87Å
291	P	98.1	Very high	97.6	Very high	21 Å²	21	51.8 Å²	51.8	14%	0.136	26%	0.256	C	S	.	.	H	α-helix	trans	-59.6	-34.3	176.2	-24.8	35.9	0	0	0	113.6	Y288 S289 I296 I297 I333 M361	Y288-P291 WeakPolarHBondContact O-CD 3.33Å; S289-P291 VanDerWaalsContact C-CD 3.45Å; P291-I296 PolarHBondContact O-N 2.98Å; P291-I297 HydrophobicContact CB-CD1 3.92Å; P291-I297 HydrophobicContact CB-CG1 4.36Å; P291-I297 PolarHBondContact O-N 2.99Å; P291-I333 HydrophobicContact CB-CG2 4.08Å; P291-I333 HydrophobicContact CG-CG2 3.83Å; P291-M361 HydrophobicContact CB-SD 3.97Å; P291-M361 HydrophobicContact CG-SD 4.06Å
292	Q	98.1	Very high	97.4	Very high	0 Å²	0	56.1 Å²	56.1	0%	0	28%	0.276	C	S	.	.	H	α-helix	trans	-79.7	-42.3	175.7	-68	-172.1	-51.2	0	0	111.6	S289 L290 L294 H295 I297 C299 N360 M361	S289-Q292 PolarHBondContact O-N 3.31Å; L290-Q292 PolarHBondContact O-N 3.27Å; Q292-L294 VanDerWaalsContact C-N 3.28Å; Q292-L294 PolarHBondContact O-N 2.99Å; Q292-H295 WeakPolarHBondContact O-CA 3.1Å; Q292-H295 PolarHBondContact O-N 3.31Å; Q292-I297 HydrophobicContact CG-CB 4.47Å; Q292-I297 HydrophobicContact CG-CG2 4.41Å; Q292-C299 HydrophobicContact CB-CB 3.94Å; Q292-C299 WeakPolarHBondContact O-CB 3.39Å; Q292-N360 PolarHBondContact NE2-OD1 2.88Å; Q292-M361 HydrophobicContact CG-CB 4.31Å; Q292-M361 HydrophobicContact CG-CG 4.4Å; Q292-M361 HydrophobicContact CG-SD 4.08Å
293	L	96.8	Very high	97.3	Very high	58 Å²	58	57.5 Å²	57.5	30%	0.304	28%	0.281	S	S	.	.	H	α-helix	trans	-60.9	-38.5	178.5	-65.1	174	0	0	0	112.1	I186 F286 S289 L290 H295	I186-L293 HydrophobicContact CD1-CD1 3.95Å; F286-L293 HydrophobicContact CD2-CD1 4.28Å; F286-L293 HydrophobicContact CE2-CD1 4.3Å; S289-L293 WeakPolarHBondContact O-CG 3.5Å; S289-L293 PolarHBondContact O-N 3.49Å; L290-L293 PolarHBondContact O-N 2.85Å; L293-H295 PolarHBondContact O-N 3.39Å; L293-H295 PolarHBondContact O-ND1 3.46Å
294	L	97	Very high	97.2	Very high	107 Å²	107	56.6 Å²	56.6	56%	0.56	28%	0.275	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.3	2.5	174.9	-62.6	179.3	0	0	0	113.7	L290 Q292 I296	L290-L294 HydrophobicContact CD1-CD1 3.99Å; L290-L294 HydrophobicContact CD1-CD2 4.48Å; L290-L294 HydrophobicContact CD1-CG 3.96Å; L290-L294 HydrophobicContact CD2-CD1 4.36Å; L290-L294 HydrophobicContact CG-CD1 3.79Å; L290-L294 HydrophobicContact CG-CG 4.15Å; L290-L294 WeakPolarHBondContact O-CB 3.35Å; L290-L294 WeakPolarHBondContact O-CG 3.47Å; L290-L294 PolarHBondContact O-N 2.87Å; Q292-L294 VanDerWaalsContact C-N 3.28Å; Q292-L294 PolarHBondContact O-N 2.99Å; L294-I296 HydrophobicContact CB-CD1 3.96Å; L294-I296 HydrophobicContact CB-CG1 3.93Å; L294-I296 HydrophobicContact CD1-CD1 4.07Å; L294-I296 PolarHBondContact O-N 3.37Å; L294-I296 VanDerWaalsContact O-N 3.1Å
295	H	96.8	Very high	97.2	Very high	137 Å²	137	52.6 Å²	52.6	63%	0.634	26%	0.257	S	S	*	.	T	Hydrogen-bonded Turn	trans	55.9	23.5	-178.3	-62.6	68.2	0	0	0	114.1	Q292 L293 I297	Q292-H295 WeakPolarHBondContact O-CA 3.1Å; Q292-H295 PolarHBondContact O-N 3.31Å; L293-H295 PolarHBondContact O-N 3.39Å; L293-H295 PolarHBondContact O-ND1 3.46Å; H295-I297 VanDerWaalsContact C-N 3.28Å
296	I	97.4	Very high	97.1	Very high	42 Å²	42	60.8 Å²	60.8	22%	0.215	29%	0.288	C	S	.	.	S	Bend	trans	-69.2	-35.8	171.5	-57	168.5	0	0	0	109.3	P291 L294 L329 I333	P291-I296 PolarHBondContact O-N 2.98Å; L294-I296 HydrophobicContact CB-CD1 3.96Å; L294-I296 HydrophobicContact CB-CG1 3.93Å; L294-I296 HydrophobicContact CD1-CD1 4.07Å; L294-I296 PolarHBondContact O-N 3.37Å; L294-I296 VanDerWaalsContact O-N 3.1Å; I296-L329 HydrophobicContact CD1-CD2 4.16Å; I296-L329 HydrophobicContact CG2-CB 4.38Å; I296-L329 HydrophobicContact CG2-CD2 4.17Å; I296-L329 HydrophobicContact CG2-CG 4.03Å; I296-I333 HydrophobicContact CD1-CD1 4.27Å; I296-I333 HydrophobicContact CG2-CD1 3.96Å
297	I	97.3	Very high	97.1	Very high	0 Å²	0	60.1 Å²	60.1	0%	0	29%	0.287	C	S	.	.	S	Bend	trans	-114.6	139.2	166.9	-64.9	170	0	0	0	107.8	P291 Q292 H295 C299 F321 L326 I333 L334 M361	P291-I297 HydrophobicContact CB-CD1 3.92Å; P291-I297 HydrophobicContact CB-CG1 4.36Å; P291-I297 PolarHBondContact O-N 2.99Å; Q292-I297 HydrophobicContact CG-CB 4.47Å; Q292-I297 HydrophobicContact CG-CG2 4.41Å; H295-I297 VanDerWaalsContact C-N 3.28Å; I297-C299 PolarHBondContact O-N 3.44Å; I297-F321 HydrophobicContact CG2-CE1 4.13Å; I297-F321 HydrophobicContact CG2-CZ 4.33Å; I297-L326 HydrophobicContact CG1-CD1 4.36Å; I297-I333 HydrophobicContact CD1-CG2 4.22Å; I297-L334 HydrophobicContact CD1-CB 4.28Å; I297-L334 HydrophobicContact CD1-CD1 3.96Å; I297-M361 HydrophobicContact CD1-CE 3.5Å; I297-M361 VanDerWaalsContact CD1-CE 3.5Å; I297-M361 HydrophobicContact CD1-SD 4.09Å
298	P	97.4	Very high	97	Very high	47 Å²	47	57.1 Å²	57.1	31%	0.305	27%	0.272	S	S	.	.			trans	-53.2	125.7	-179.8	-31.2	39.2	0	0	0	113.5	S319 F321	P298-S319 PolarHBondContact O-OG 3.44Å; P298-F321 HydrophobicContact CB-CB 4.31Å; P298-F321 HydrophobicContact CB-CD1 3.94Å; P298-F321 HydrophobicContact CB-CG 4.28Å; P298-F321 HydrophobicContact CG-CB 3.83Å; P298-F321 HydrophobicContact CG-CD1 3.7Å; P298-F321 HydrophobicContact CG-CD2 4.23Å; P298-F321 HydrophobicContact CG-CE1 4.33Å; P298-F321 HydrophobicContact CG-CG 3.65Å
299	C	97.4	Very high	97	Very high	37 Å²	37	62.6 Å²	62.6	25%	0.25	30%	0.301	C	S	.	.			trans	-108.4	110.9	-176.2	-171.7	0	0	0	0	110	Q292 I297	Q292-C299 HydrophobicContact CB-CB 3.94Å; Q292-C299 WeakPolarHBondContact O-CB 3.39Å; I297-C299 PolarHBondContact O-N 3.44Å
300	P	95.8	Very high	96.9	Very high	41 Å²	41	72.2 Å²	72.2	27%	0.266	34%	0.343	S	S	.	.			trans	-71.5	154.9	175	29.6	-31.5	0	0	0	110.4	H302 R303 N360	P300-H302 VanDerWaalsContact C-N 3.27Å; P300-H302 PolarHBondContact O-N 3.23Å; P300-R303 HydrophobicContact CG-CG 3.96Å; P300-N360 WeakPolarHBondContact CD-OD1 3.24Å; P300-N360 WeakPolarHBondContact CG-OD1 3.44Å
301	R	92	Very high	96.8	Very high	211 Å²	211	73 Å²	73	80%	0.796	35%	0.35	S	S	*	.	S	Bend	trans	-55.7	-41.9	179.6	-177.2	177	178.8	93.7	1.3	112.7
302	H	93.9	Very high	96.7	Very high	102 Å²	102	73.6 Å²	73.6	47%	0.472	36%	0.36	S	S	.	.			trans	-116.7	121.3	176.9	-61.4	-71.7	0	0	0	109.6	P300 I304	P300-H302 VanDerWaalsContact C-N 3.27Å; P300-H302 PolarHBondContact O-N 3.23Å; H302-I304 HydrophobicContact CB-CG1 4.34Å
303	R	97	Very high	96.7	Very high	28 Å²	28	78 Å²	78	11%	0.106	38%	0.379	C	S	.	.			trans	-105.7	11.7	179.1	-61.8	-171.3	-65.3	146.1	7	113.1	S289 P300 S317 N360 M361 T362 N365	S289-R303 VanDerWaalsContact CB-NH1 3.3Å; S289-R303 PolarHBondContact OG-NH1 3.25Å; S289-R303 PolarHBondContact OG-NH2 3.37Å; S289-R303 VanDerWaalsContact OG-NH2 3.17Å; P300-R303 HydrophobicContact CG-CG 3.96Å; R303-S317 PolarHBondContact O-OG 2.9Å; R303-N360 HydrophobicContact CB-CB 4.16Å; R303-N360 HydrophobicContact CG-CB 4.49Å; R303-M361 PolarHBondContact NH1-O 3.05Å; R303-M361 VanDerWaalsContact NH1-O 3.07Å; R303-T362 HydrophobicContact CB-CG2 3.79Å; R303-N365 PolarHBondContact O-ND2 3.4Å
304	I	96.8	Very high	96.8	Very high	27 Å²	27	75.3 Å²	75.3	14%	0.138	37%	0.365	C	S	.	.			trans	-64.3	155.2	176	63.3	177.3	0	0	0	110.6	L46 H302 S317	L46-I304 HydrophobicContact CB-CD1 3.46Å; L46-I304 VanDerWaalsContact CB-CD1 3.46Å; L46-I304 HydrophobicContact CD1-CD1 3.61Å; L46-I304 HydrophobicContact CG-CD1 4.18Å; H302-I304 HydrophobicContact CB-CG1 4.34Å; I304-S317 WeakPolarHBondContact O-CB 3.34Å; I304-S317 PolarHBondContact O-OG 2.87Å
305	P	98	Very high	96.9	Very high	1 Å²	1	73.4 Å²	73.4	1%	0.006	35%	0.353	C	S	.	.			trans	-62.7	168.2	174.7	28.8	-38	0	0	0	112.2	N47 I190 L314 E315 I364 L368	N47-P305 PolarHBondContact OD1-O 3.04Å; I190-P305 HydrophobicContact CG2-CG 4.08Å; P305-L314 HydrophobicContact CB-CB 4.04Å; P305-L314 HydrophobicContact CG-CB 4.14Å; P305-L314 HydrophobicContact CG-CD1 3.76Å; P305-L314 HydrophobicContact CG-CD2 4.42Å; P305-L314 HydrophobicContact CG-CG 4.33Å; P305-E315 WeakPolarHBondContact CA-O 3.45Å; P305-E315 WeakPolarHBondContact CB-O 3.32Å; P305-I364 HydrophobicContact CG-CG2 4.01Å; P305-L368 HydrophobicContact CB-CD1 3.5Å; P305-L368 HydrophobicContact CG-CD1 4.29Å
306	R	97.2	Very high	97	Very high	172 Å²	172	68.8 Å²	68.8	65%	0.649	33%	0.332	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-104.8	134.8	177.9	-67.5	-64.2	-173	173.6	-0.1	110.5	N308 L314 E315	R306-N308 PolarHBondContact O-N 2.88Å; R306-L314 WeakPolarHBondContact O-CA 3.35Å; R306-E315 PolarHBondContact N-O 2.77Å; R306-E315 PolarHBondContact O-N 3.5Å
307	L	98	Very high	97	Very high	49 Å²	49	67 Å²	67	26%	0.257	32%	0.323	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-73.8	123.6	171.5	178.2	71.3	0	0	0	110.2	N47 T49 L314	N47-L307 WeakPolarHBondContact O-CD2 3.22Å; T49-L307 HydrophobicContact CG2-CD2 4Å; L307-L314 HydrophobicContact CB-CD2 4.25Å; L307-L314 HydrophobicContact CD1-CD2 4.3Å
308	N	97.9	Very high	97	Very high	42 Å²	42	70.1 Å²	70.1	23%	0.225	34%	0.336	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.3	110.6	163.1	-178.2	-28	0	0	0	109.3	R306 K310 T311 G312 K313 E315	R306-N308 PolarHBondContact O-N 2.88Å; N308-K310 PolarHBondContact O-N 3.1Å; N308-K310 WeakPolarHBondContact OD1-CB 3.37Å; N308-K310 PolarHBondContact OD1-N 3.06Å; N308-T311 WeakPolarHBondContact CB-OG1 3.36Å; N308-T311 PolarHBondContact O-N 3.35Å; N308-T311 PolarHBondContact O-OG1 3.43Å; N308-T311 PolarHBondContact OD1-N 3.2Å; N308-G312 PolarHBondContact O-N 3.16Å; N308-K313 PolarHBondContact N-O 2.67Å; N308-E315 HydrophobicContact CB-CG 4.13Å; N308-E315 WeakPolarHBondContact CB-OE1 3.23Å; N308-E315 PolarHBondContact ND2-OE1 3.48Å
309	I	96.6	Very high	97	Very high	134 Å²	134	68.4 Å²	68.4	69%	0.687	32%	0.324	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.3	-31.2	-174.3	-55.3	170.8	0	0	0	111.7	T49	T49-I309 HydrophobicContact CG2-CG1 4.43Å; T49-I309 HydrophobicContact CG2-CG2 4.19Å
310	K	96.9	Very high	96.9	Very high	203 Å²	203	71.8 Å²	71.8	88%	0.883	34%	0.335	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.3	-38.3	-178.6	-62.4	-178	179.5	179.2	0	111.9	N308	N308-K310 PolarHBondContact O-N 3.1Å; N308-K310 WeakPolarHBondContact OD1-CB 3.37Å; N308-K310 PolarHBondContact OD1-N 3.06Å
311	T	96.8	Very high	96.9	Very high	74 Å²	74	70.5 Å²	70.5	45%	0.454	33%	0.325	S	S	.	.	T	Hydrogen-bonded Turn	trans	-92.9	-20.7	-177	64.8	0	0	0	0	112.9	N308 K313	N308-T311 WeakPolarHBondContact CB-OG1 3.36Å; N308-T311 PolarHBondContact O-N 3.35Å; N308-T311 PolarHBondContact O-OG1 3.43Å; N308-T311 PolarHBondContact OD1-N 3.2Å; T311-K313 PolarHBondContact O-N 3.02Å; T311-K313 PolarHBondContact OG1-N 3.45Å
312	G	96.3	Very high	97	Very high	34 Å²	34	65.6 Å²	65.6	35%	0.351	31%	0.31	S	S	.	.	T	Hydrogen-bonded Turn	trans	68.3	17.4	-172.6	0	0	0	0	0	113.6	N308 H375	N308-G312 PolarHBondContact O-N 3.16Å; G312-H375 PolarHBondContact O-ND1 3.24Å
313	K	98.4	Very high	96.9	Very high	92 Å²	92	62.7 Å²	62.7	40%	0.4	30%	0.299	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.1	158.7	-178.3	-63.1	-178.2	179.9	-177.6	0	111.2	N308 T311 P373 H375	N308-K313 PolarHBondContact N-O 2.67Å; T311-K313 PolarHBondContact O-N 3.02Å; T311-K313 PolarHBondContact OG1-N 3.45Å; K313-P373 HydrophobicContact CB-CB 4.11Å; K313-P373 HydrophobicContact CD-CB 4.24Å; K313-P373 WeakPolarHBondContact CD-O 3.2Å; K313-H375 HydrophobicContact CG-CB 4.44Å
314	L	98.7	Very high	96.7	Very high	1 Å²	1	70.2 Å²	70.2	1%	0.005	33%	0.333	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-85.9	133.9	173.2	-60.7	-179.8	0	0	0	110.1	N47 I190 P305 R306 L307 L368 P373 I374 E376 L379	N47-L314 HydrophobicContact CB-CD2 3.96Å; I190-L314 HydrophobicContact CG2-CD1 3.93Å; P305-L314 HydrophobicContact CB-CB 4.04Å; P305-L314 HydrophobicContact CG-CB 4.14Å; P305-L314 HydrophobicContact CG-CD1 3.76Å; P305-L314 HydrophobicContact CG-CD2 4.42Å; P305-L314 HydrophobicContact CG-CG 4.33Å; R306-L314 WeakPolarHBondContact O-CA 3.35Å; L307-L314 HydrophobicContact CB-CD2 4.25Å; L307-L314 HydrophobicContact CD1-CD2 4.3Å; L314-L368 HydrophobicContact CB-CD1 4.31Å; L314-L368 WeakPolarHBondContact O-CD2 3.42Å; L314-P373 VanDerWaalsContact O-CA 3.29Å; L314-P373 WeakPolarHBondContact O-CA 3.37Å; L314-I374 WeakPolarHBondContact CB-O 3.18Å; L314-I374 PolarHBondContact N-O 3.32Å; L314-I374 PolarHBondContact O-N 3.49Å; L314-E376 HydrophobicContact CD1-CB 3.69Å; L314-E376 HydrophobicContact CD1-CG 3.85Å; L314-E376 HydrophobicContact CG-CB 4.18Å; L314-L379 HydrophobicContact CB-CD2 4.47Å; L314-L379 HydrophobicContact CD1-CD2 3.93Å
315	E	98.4	Very high	96.5	Very high	68 Å²	68	72.9 Å²	72.9	32%	0.318	35%	0.354	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.8	161.4	176.3	-67.1	-179.4	179.7	0	0	110	P305 R306 N308 S317 P373	P305-E315 WeakPolarHBondContact CA-O 3.45Å; P305-E315 WeakPolarHBondContact CB-O 3.32Å; R306-E315 PolarHBondContact N-O 2.77Å; R306-E315 PolarHBondContact O-N 3.5Å; N308-E315 HydrophobicContact CB-CG 4.13Å; N308-E315 WeakPolarHBondContact CB-OE1 3.23Å; N308-E315 PolarHBondContact ND2-OE1 3.48Å; E315-S317 PolarHBondContact O-N 2.96Å; E315-P373 HydrophobicContact CG-CB 3.92Å; E315-P373 HydrophobicContact CG-CG 3.96Å
316	M	98.1	Very high	96.4	Very high	40 Å²	40	74 Å²	74	20%	0.197	36%	0.359	C	S	.	.			trans	-56.1	141.1	177.7	-72.4	-176.6	-76.1	0	0	111	Y318 N359 N365 L368 K369	M316-Y318 HydrophobicContact CB-CD2 4.48Å; M316-Y318 HydrophobicContact CB-CE2 3.78Å; M316-Y318 WeakPolarHBondContact CE-OH 3.33Å; M316-N359 HydrophobicContact SD-CB 4.39Å; M316-N365 WeakPolarHBondContact CA-OD1 3.46Å; M316-L368 HydrophobicContact CG-CB 3.78Å; M316-K369 HydrophobicContact CE-CB 4.46Å; M316-K369 VanDerWaalsContact SD-CA 3.57Å; M316-K369 HydrophobicContact SD-CB 3.52Å; M316-K369 VanDerWaalsContact SD-CB 3.52Å; M316-K369 HydrophobicContact SD-CG 4.02Å
317	S	97.9	Very high	96.3	Very high	3 Å²	3	68.4 Å²	68.4	2%	0.021	35%	0.347	C	S	.	.			trans	-98.1	153	166.6	67.5	0	0	0	0	110.9	R303 I304 E315 N360 N365	R303-S317 PolarHBondContact O-OG 2.9Å; I304-S317 WeakPolarHBondContact O-CB 3.34Å; I304-S317 PolarHBondContact O-OG 2.87Å; E315-S317 PolarHBondContact O-N 2.96Å; S317-N360 PolarHBondContact O-N 3.5Å; S317-N360 PolarHBondContact OG-ND2 3.33Å; S317-N365 PolarHBondContact N-OD1 3.29Å; S317-N365 PolarHBondContact OG-OD1 2.99Å
318	Y	97.8	Very high	96.2	Very high	67 Å²	67	74.8 Å²	74.8	26%	0.263	37%	0.373	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.4	157	-174.1	-65.8	-100.8	0	0	0	111.6	M316 T344 H346 E357 C358 N359	M316-Y318 HydrophobicContact CB-CD2 4.48Å; M316-Y318 HydrophobicContact CB-CE2 3.78Å; M316-Y318 WeakPolarHBondContact CE-OH 3.33Å; Y318-T344 HydrophobicContact CE1-CG2 4.5Å; Y318-H346 AromaticContact CE1-CD2 3.49Å; Y318-H346 VanDerWaalsContact CE1-CD2 3.49Å; Y318-H346 WeakPolarHBondContact CE1-CD2 3.5Å; Y318-H346 AromaticContact CE1-NE2 3.65Å; Y318-H346 AromaticContact CZ-NE2 3.82Å; Y318-H346 PolarHBondContact OH-NE2 3.43Å; Y318-E357 VanDerWaalsContact CB-CG 3.46Å; Y318-E357 WeakPolarHBondContact CB-OE1 3.31Å; Y318-E357 HydrophobicContact CD1-CG 3.87Å; Y318-E357 HydrophobicContact CG-CG 3.96Å; Y318-C358 CarbonylContact C-O 3.59Å; Y318-C358 VanDerWaalsContact CA-O 3.29Å; Y318-C358 WeakPolarHBondContact CA-O 3.46Å; Y318-N359 HydrophobicContact CD1-CB 4.1Å; Y318-N359 HydrophobicContact CE1-CB 4.03Å
319	S	97	Very high	96.1	Very high	10 Å²	10	77.1 Å²	77.1	7%	0.07	39%	0.385	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.2	112	173.3	-173.1	0	0	0	0	108.3	P298 F321 E357 C358	P298-S319 PolarHBondContact O-OG 3.44Å; S319-F321 WeakPolarHBondContact O-CD1 3.25Å; S319-F321 WeakPolarHBondContact O-CE1 3.44Å; S319-E357 WeakPolarHBondContact O-CA 3.21Å; S319-C358 PolarHBondContact N-O 2.92Å; S319-C358 PolarHBondContact O-N 2.91Å; S319-C358 VanDerWaalsContact O-N 3.08Å
320	K	95.6	Very high	96.1	Very high	108 Å²	108	70.8 Å²	70.8	47%	0.47	35%	0.352	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.4	129.5	179.3	-176.8	176	-179.5	175.4	0	110.4	F355 E357	K320-F355 HydrophobicContact CD-CD1 4.43Å; K320-F355 VanDerWaalsContact CE-CB 3.5Å; K320-F355 VanDerWaalsContact CE-CG 3.46Å; K320-F355 HydrophobicContact CG-CB 4.21Å; K320-F355 HydrophobicContact CG-CD1 4.05Å; K320-F355 HydrophobicContact CG-CG 4.44Å; K320-E357 HydrophobicContact CB-CB 4.33Å; K320-E357 HydrophobicContact CB-CG 4.3Å; K320-E357 HydrophobicContact CG-CB 4.46Å
321	F	95.4	Very high	96.1	Very high	14 Å²	14	63.5 Å²	63.5	6%	0.061	33%	0.325	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-149.7	160.3	179	50.3	-93.2	0	0	0	111.7	I297 P298 S319 T323 L326 L334 F355 T356	I297-F321 HydrophobicContact CG2-CE1 4.13Å; I297-F321 HydrophobicContact CG2-CZ 4.33Å; P298-F321 HydrophobicContact CB-CB 4.31Å; P298-F321 HydrophobicContact CB-CD1 3.94Å; P298-F321 HydrophobicContact CB-CG 4.28Å; P298-F321 HydrophobicContact CG-CB 3.83Å; P298-F321 HydrophobicContact CG-CD1 3.7Å; P298-F321 HydrophobicContact CG-CD2 4.23Å; P298-F321 HydrophobicContact CG-CE1 4.33Å; P298-F321 HydrophobicContact CG-CG 3.65Å; S319-F321 WeakPolarHBondContact O-CD1 3.25Å; S319-F321 WeakPolarHBondContact O-CE1 3.44Å; F321-T323 PolarHBondContact O-N 3.24Å; F321-L326 HydrophobicContact CE2-CB 4.31Å; F321-L326 HydrophobicContact CE2-CD1 4.03Å; F321-L326 HydrophobicContact CE2-CD2 3.97Å; F321-L326 HydrophobicContact CE2-CG 4.34Å; F321-L326 HydrophobicContact CZ-CD1 4.44Å; F321-L326 HydrophobicContact CZ-CD2 4.43Å; F321-L334 HydrophobicContact CZ-CD2 4.42Å; F321-F355 WeakPolarHBondContact O-CA 3.4Å; F321-T356 HydrophobicContact CE2-CG2 4.13Å; F321-T356 HydrophobicContact CZ-CG2 4.04Å; F321-T356 PolarHBondContact N-O 2.96Å; F321-T356 PolarHBondContact O-N 3.29Å
322	K	94.4	Very high	96.1	Very high	108 Å²	108	65.7 Å²	65.7	47%	0.47	33%	0.328	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-68.6	125.3	178	-69.6	-167	177.6	-156.6	0	109.5	K324 S325 D352 F355	K322-K324 PolarHBondContact O-N 2.9Å; K322-S325 WeakPolarHBondContact O-CB 3.25Å; K322-S325 PolarHBondContact O-N 3.19Å; K322-S325 PolarHBondContact O-OG 3.26Å; K322-D352 PolarHBondContact NZ-O 3.35Å; K322-F355 HydrophobicContact CD-CE1 4.48Å; K322-F355 HydrophobicContact CD-CZ 4.48Å; K322-F355 HydrophobicContact CG-CD1 4.01Å; K322-F355 HydrophobicContact CG-CE1 3.49Å; K322-F355 VanDerWaalsContact CG-CE1 3.49Å; K322-F355 HydrophobicContact CG-CZ 3.9Å
323	T	92.4	Very high	96.2	Very high	42 Å²	42	66 Å²	66	26%	0.258	32%	0.322	S	S	.	.	G	3₁₀ helix	trans	-55.6	-40.4	-175.6	-53.5	0	0	0	0	111.9	F321 S325 L326 E354 F355 T356	F321-T323 PolarHBondContact O-N 3.24Å; T323-S325 PolarHBondContact O-N 3.28Å; T323-L326 PolarHBondContact O-N 3.28Å; T323-E354 PolarHBondContact N-O 2.85Å; T323-E354 PolarHBondContact OG1-O 3.07Å; T323-F355 VanDerWaalsContact OG1-C 3.31Å; T323-T356 PolarHBondContact OG1-N 2.97Å; T323-T356 PolarHBondContact OG1-OG1 3.11Å
324	K	92	Very high	96.1	Very high	186 Å²	186	62.1 Å²	62.1	81%	0.809	31%	0.305	S	S	*	.	G	3₁₀ helix	trans	-67.4	-16.8	179.6	-63.5	-176.3	-179.8	176.9	0	114.6	K322	K322-K324 PolarHBondContact O-N 2.9Å
325	S	92.9	Very high	95.9	Very high	82 Å²	82	68.6 Å²	68.6	57%	0.573	33%	0.333	S	S	*	.	G	3₁₀ helix	trans	-84.2	-13.3	178.7	68.1	0	0	0	0	113.3	K322 T323	K322-S325 WeakPolarHBondContact O-CB 3.25Å; K322-S325 PolarHBondContact O-N 3.19Å; K322-S325 PolarHBondContact O-OG 3.26Å; T323-S325 PolarHBondContact O-N 3.28Å
326	L	94.8	Very high	95.9	Very high	24 Å²	24	68.1 Å²	68.1	13%	0.126	34%	0.335	C	S	.	.	S	Bend	trans	-77.3	133.5	-177	-166	66.7	0	0	0	110.7	I297 F321 T323 L334	I297-L326 HydrophobicContact CG1-CD1 4.36Å; F321-L326 HydrophobicContact CE2-CB 4.31Å; F321-L326 HydrophobicContact CE2-CD1 4.03Å; F321-L326 HydrophobicContact CE2-CD2 3.97Å; F321-L326 HydrophobicContact CE2-CG 4.34Å; F321-L326 HydrophobicContact CZ-CD1 4.44Å; F321-L326 HydrophobicContact CZ-CD2 4.43Å; T323-L326 PolarHBondContact O-N 3.28Å; L326-L334 HydrophobicContact CD2-CD2 4.2Å
327	S	96.1	Very high	95.8	Very high	56 Å²	56	66.8 Å²	66.8	39%	0.392	33%	0.33	S	S	.	.			trans	-63.1	160.2	175.9	67.6	0	0	0	0	112	L329 G330 T331	S327-L329 VanDerWaalsContact C-N 3.28Å; S327-L329 PolarHBondContact O-N 3.12Å; S327-G330 PolarHBondContact O-N 3.14Å; S327-G330 PolarHBondContact OG-N 3.27Å; S327-T331 PolarHBondContact O-N 2.97Å; S327-T331 PolarHBondContact O-OG1 3.22Å
328	F	96.4	Very high	95.8	Very high	183 Å²	183	71 Å²	71	80%	0.803	35%	0.35	S	S	*	.	H	α-helix	trans	-55.7	-45.2	173.2	175.7	-96.3	0	0	0	111.6	T331 F332	F328-T331 PolarHBondContact O-N 3.4Å; F328-F332 WeakPolarHBondContact O-CB 3.38Å; F328-F332 PolarHBondContact O-N 3.46Å
329	L	96.1	Very high	95.7	Very high	91 Å²	91	72.1 Å²	72.1	48%	0.476	37%	0.367	S	S	.	.	H	α-helix	trans	-61.9	-44.4	177	-178.7	62.2	0	0	0	111.6	I296 S327 T331 F332 I333	I296-L329 HydrophobicContact CD1-CD2 4.16Å; I296-L329 HydrophobicContact CG2-CB 4.38Å; I296-L329 HydrophobicContact CG2-CD2 4.17Å; I296-L329 HydrophobicContact CG2-CG 4.03Å; S327-L329 VanDerWaalsContact C-N 3.28Å; S327-L329 PolarHBondContact O-N 3.12Å; L329-T331 VanDerWaalsContact C-N 3.34Å; L329-T331 PolarHBondContact O-N 3.28Å; L329-F332 PolarHBondContact O-N 3.02Å; L329-I333 HydrophobicContact CD1-CD1 4.03Å; L329-I333 HydrophobicContact CD1-CG1 4.25Å; L329-I333 HydrophobicContact CG-CD1 3.88Å; L329-I333 HydrophobicContact CG-CG1 4.48Å; L329-I333 VanDerWaalsContact O-CG1 3.3Å; L329-I333 WeakPolarHBondContact O-CG1 3.26Å; L329-I333 PolarHBondContact O-N 3.25Å
330	G	96.3	Very high	95.7	Very high	0 Å²	0	77 Å²	77	0%	0	39%	0.392	C	S	.	.	H	α-helix	trans	-61.7	-42.2	176.8	0	0	0	0	0	112.4	S327 I333 L334	S327-G330 PolarHBondContact O-N 3.14Å; S327-G330 PolarHBondContact OG-N 3.27Å; G330-I333 PolarHBondContact O-N 2.87Å; G330-L334 WeakPolarHBondContact O-CB 3.45Å; G330-L334 PolarHBondContact O-N 3.2Å
331	T	96	Very high	95.7	Very high	50 Å²	50	81.6 Å²	81.6	31%	0.307	41%	0.406	S	S	.	.	H	α-helix	trans	-63.4	-43.5	176.5	-54.4	0	0	0	0	111.5	S327 F328 L329 L334 K335	S327-T331 PolarHBondContact O-N 2.97Å; S327-T331 PolarHBondContact O-OG1 3.22Å; F328-T331 PolarHBondContact O-N 3.4Å; L329-T331 VanDerWaalsContact C-N 3.34Å; L329-T331 PolarHBondContact O-N 3.28Å; T331-L334 PolarHBondContact O-N 3.37Å; T331-K335 HydrophobicContact CG2-CD 4.49Å; T331-K335 WeakPolarHBondContact O-CG 3.44Å; T331-K335 PolarHBondContact O-N 3.48Å
332	F	97.4	Very high	95.8	Very high	120 Å²	120	83.6 Å²	83.6	53%	0.526	42%	0.417	S	S	.	.	H	α-helix	trans	-62.3	-51	176.8	175.3	-101.5	0	0	0	111.8	F328 L329 L334 K335 V336	F328-F332 WeakPolarHBondContact O-CB 3.38Å; F328-F332 PolarHBondContact O-N 3.46Å; L329-F332 PolarHBondContact O-N 3.02Å; F332-L334 VanDerWaalsContact C-N 3.27Å; F332-L334 PolarHBondContact O-N 3.42Å; F332-K335 PolarHBondContact O-N 3.45Å; F332-V336 HydrophobicContact CD1-CG2 4.43Å; F332-V336 HydrophobicContact CD2-CG2 4.37Å; F332-V336 HydrophobicContact CE1-CG2 4.02Å; F332-V336 HydrophobicContact CE2-CG2 3.95Å; F332-V336 HydrophobicContact CZ-CG2 3.76Å; F332-V336 WeakPolarHBondContact O-CG2 3.33Å; F332-V336 PolarHBondContact O-N 3.39Å
333	I	97.3	Very high	95.8	Very high	42 Å²	42	78.8 Å²	78.8	22%	0.215	40%	0.397	C	S	.	.	H	α-helix	trans	-57.5	-44.2	177.9	-69.6	170	0	0	0	110.5	P291 I296 I297 L329 G330 V336 A337	P291-I333 HydrophobicContact CB-CG2 4.08Å; P291-I333 HydrophobicContact CG-CG2 3.83Å; I296-I333 HydrophobicContact CD1-CD1 4.27Å; I296-I333 HydrophobicContact CG2-CD1 3.96Å; I297-I333 HydrophobicContact CD1-CG2 4.22Å; L329-I333 HydrophobicContact CD1-CD1 4.03Å; L329-I333 HydrophobicContact CD1-CG1 4.25Å; L329-I333 HydrophobicContact CG-CD1 3.88Å; L329-I333 HydrophobicContact CG-CG1 4.48Å; L329-I333 VanDerWaalsContact O-CG1 3.3Å; L329-I333 WeakPolarHBondContact O-CG1 3.26Å; L329-I333 PolarHBondContact O-N 3.25Å; G330-I333 PolarHBondContact O-N 2.87Å; I333-V336 PolarHBondContact O-N 2.9Å; I333-A337 WeakPolarHBondContact O-CB 3.33Å; I333-A337 PolarHBondContact O-N 2.96Å
334	L	96.1	Very high	96	Very high	10 Å²	10	78.3 Å²	78.3	5%	0.052	39%	0.394	C	S	.	.	H	α-helix	trans	-63.7	-43.7	-178.5	-166.8	72.3	0	0	0	111.6	I297 F321 L326 G330 T331 F332 A337 E338 V343 I345 T356 C358 M361	I297-L334 HydrophobicContact CD1-CB 4.28Å; I297-L334 HydrophobicContact CD1-CD1 3.96Å; F321-L334 HydrophobicContact CZ-CD2 4.42Å; L326-L334 HydrophobicContact CD2-CD2 4.2Å; G330-L334 WeakPolarHBondContact O-CB 3.45Å; G330-L334 PolarHBondContact O-N 3.2Å; T331-L334 PolarHBondContact O-N 3.37Å; F332-L334 VanDerWaalsContact C-N 3.27Å; F332-L334 PolarHBondContact O-N 3.42Å; L334-A337 PolarHBondContact O-N 2.89Å; L334-E338 WeakPolarHBondContact O-CB 3.49Å; L334-E338 PolarHBondContact O-N 3.25Å; L334-V343 HydrophobicContact CD1-CG1 4.18Å; L334-I345 HydrophobicContact CD1-CD1 4.05Å; L334-I345 HydrophobicContact CD2-CD1 3.81Å; L334-I345 HydrophobicContact CG-CD1 3.52Å; L334-I345 HydrophobicContact CG-CG1 4.44Å; L334-T356 HydrophobicContact CD2-CG2 3.96Å; L334-C358 HydrophobicContact CD1-CB 3.77Å; L334-M361 HydrophobicContact CD1-CE 4.11Å
335	K	96.1	Very high	96.2	Very high	137 Å²	137	70.8 Å²	70.8	60%	0.596	36%	0.362	S	S	*	.	H	α-helix	trans	-63.7	-41	175	-75.8	-177.8	176.5	-175.6	0	113	T331 F332 E338 S339	T331-K335 HydrophobicContact CG2-CD 4.49Å; T331-K335 WeakPolarHBondContact O-CG 3.44Å; T331-K335 PolarHBondContact O-N 3.48Å; F332-K335 PolarHBondContact O-N 3.45Å; K335-E338 PolarHBondContact O-N 3.26Å; K335-S339 PolarHBondContact O-N 3.41Å
336	V	97.4	Very high	96.3	Very high	58 Å²	58	71 Å²	71	35%	0.352	35%	0.354	S	S	.	.	H	α-helix	trans	-65.6	-43	175.9	172.4	0	0	0	0	110.7	F332 I333 E338 S339 L340	F332-V336 HydrophobicContact CD1-CG2 4.43Å; F332-V336 HydrophobicContact CD2-CG2 4.37Å; F332-V336 HydrophobicContact CE1-CG2 4.02Å; F332-V336 HydrophobicContact CE2-CG2 3.95Å; F332-V336 HydrophobicContact CZ-CG2 3.76Å; F332-V336 WeakPolarHBondContact O-CG2 3.33Å; F332-V336 PolarHBondContact O-N 3.39Å; I333-V336 PolarHBondContact O-N 2.9Å; V336-E338 VanDerWaalsContact C-N 3.32Å; V336-E338 PolarHBondContact O-N 3.37Å; V336-S339 PolarHBondContact O-N 2.79Å; V336-S339 PolarHBondContact O-OG 3.15Å; V336-L340 HydrophobicContact CG1-CD1 4.09Å; V336-L340 WeakPolarHBondContact O-CB 3.41Å; V336-L340 WeakPolarHBondContact O-CG 3.3Å; V336-L340 PolarHBondContact O-N 3.4Å
337	A	97.1	Very high	96.3	Very high	12 Å²	12	77.6 Å²	77.6	10%	0.099	38%	0.384	C	S	.	.	H	α-helix	trans	-67.1	-34.4	178.6	0	0	0	0	0	112.4	I333 L334 R341 L342 V343 M361	I333-A337 WeakPolarHBondContact O-CB 3.33Å; I333-A337 PolarHBondContact O-N 2.96Å; L334-A337 PolarHBondContact O-N 2.89Å; A337-R341 PolarHBondContact O-N 3.15Å; A337-L342 WeakPolarHBondContact O-CB 3.43Å; A337-L342 PolarHBondContact O-N 2.79Å; A337-V343 HydrophobicContact CB-CB 4.3Å; A337-V343 HydrophobicContact CB-CG2 3.64Å; A337-V343 PolarHBondContact O-N 3.14Å; A337-M361 HydrophobicContact CB-CE 4.47Å
338	E	96.6	Very high	96.1	Very high	91 Å²	91	76.9 Å²	76.9	43%	0.425	38%	0.379	S	S	.	.	H	α-helix	trans	-66.2	-45.7	172.2	-176.6	177.1	-140.9	0	0	112	L334 K335 V336 L340 R341 I345	L334-E338 WeakPolarHBondContact O-CB 3.49Å; L334-E338 PolarHBondContact O-N 3.25Å; K335-E338 PolarHBondContact O-N 3.26Å; V336-E338 VanDerWaalsContact C-N 3.32Å; V336-E338 PolarHBondContact O-N 3.37Å; E338-L340 VanDerWaalsContact C-N 3.29Å; E338-L340 PolarHBondContact O-N 2.97Å; E338-R341 WeakPolarHBondContact O-CA 3.35Å; E338-R341 PolarHBondContact O-N 3.41Å; E338-I345 HydrophobicContact CB-CD1 3.81Å; E338-I345 HydrophobicContact CG-CD1 4.07Å
339	S	97.1	Very high	95.9	Very high	90 Å²	90	74.1 Å²	74.1	63%	0.629	37%	0.373	S	S	*	.	H	α-helix	trans	-64.5	-34.3	179.2	73.7	0	0	0	0	112.5	K335 V336 R341	K335-S339 PolarHBondContact O-N 3.41Å; V336-S339 PolarHBondContact O-N 2.79Å; V336-S339 PolarHBondContact O-OG 3.15Å; S339-R341 PolarHBondContact O-N 3.14Å
340	L	96.6	Very high	95.6	Very high	112 Å²	112	72.5 Å²	72.5	59%	0.586	37%	0.367	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75	2.1	170.9	-66.5	176.3	0	0	0	113.6	V336 E338 L342	V336-L340 HydrophobicContact CG1-CD1 4.09Å; V336-L340 WeakPolarHBondContact O-CB 3.41Å; V336-L340 WeakPolarHBondContact O-CG 3.3Å; V336-L340 PolarHBondContact O-N 3.4Å; E338-L340 VanDerWaalsContact C-N 3.29Å; E338-L340 PolarHBondContact O-N 2.97Å; L340-L342 HydrophobicContact CB-CD1 4.03Å; L340-L342 HydrophobicContact CB-CG 3.94Å; L340-L342 HydrophobicContact CD1-CD1 4.21Å; L340-L342 PolarHBondContact O-N 3.46Å
341	R	95.9	Very high	95.2	Very high	206 Å²	206	82.4 Å²	82.4	78%	0.777	41%	0.413	S	S	*	.	T	Hydrogen-bonded Turn	trans	56.5	28.4	-177.3	-54.8	-178.2	177.3	-172.6	-1.1	113.4	A337 E338 S339 K369	A337-R341 PolarHBondContact O-N 3.15Å; E338-R341 WeakPolarHBondContact O-CA 3.35Å; E338-R341 PolarHBondContact O-N 3.41Å; S339-R341 PolarHBondContact O-N 3.14Å; R341-K369 VanDerWaalsContact O-CE 3.26Å; R341-K369 WeakPolarHBondContact O-CE 3.24Å; R341-K369 PolarHBondContact O-NZ 2.95Å
342	L	96.1	Very high	94.6	Very high	56 Å²	56	85.9 Å²	85.9	29%	0.293	43%	0.43	S	S	.	.			trans	-85.9	-31.6	176.6	-62.4	175	0	0	0	111.7	Y288 A337 L340	Y288-L342 HydrophobicContact CE2-CB 4.05Å; Y288-L342 PolarHBondContact OH-O 3.32Å; A337-L342 WeakPolarHBondContact O-CB 3.43Å; A337-L342 PolarHBondContact O-N 2.79Å; L340-L342 HydrophobicContact CB-CD1 4.03Å; L340-L342 HydrophobicContact CB-CG 3.94Å; L340-L342 HydrophobicContact CD1-CD1 4.21Å; L340-L342 PolarHBondContact O-N 3.46Å
343	V	96.3	Very high	94.2	Very high	6 Å²	6	81.6 Å²	81.6	4%	0.036	42%	0.419	C	S	.	.			trans	-118	142.1	-177	179.8	0	0	0	0	110.2	Y288 L334 A337 I345 C358 M361	Y288-V343 HydrophobicContact CE2-CG2 4.33Å; L334-V343 HydrophobicContact CD1-CG1 4.18Å; A337-V343 HydrophobicContact CB-CB 4.3Å; A337-V343 HydrophobicContact CB-CG2 3.64Å; A337-V343 PolarHBondContact O-N 3.14Å; V343-I345 HydrophobicContact CG1-CG1 3.89Å; V343-C358 HydrophobicContact CG1-CB 3.95Å; V343-M361 HydrophobicContact CG2-CE 3.58Å; V343-M361 HydrophobicContact CG2-CG 4.27Å
344	T	96.2	Very high	94	Very high	33 Å²	33	84.4 Å²	84.4	20%	0.202	43%	0.431	C	S	.	.			trans	-99.4	127.8	167.2	-51.7	0	0	0	0	108.3	Y318 H346 C358 N359 K369	Y318-T344 HydrophobicContact CE1-CG2 4.5Å; T344-H346 WeakPolarHBondContact CG2-NE2 3.45Å; T344-C358 WeakPolarHBondContact O-CA 3.27Å; T344-N359 PolarHBondContact N-ND2 3.19Å; T344-N359 PolarHBondContact O-N 3.12Å; T344-K369 VanDerWaalsContact OG1-CE 3.27Å; T344-K369 WeakPolarHBondContact OG1-CE 3.44Å
345	I	96	Very high	94	Very high	27 Å²	27	85.4 Å²	85.4	14%	0.138	44%	0.435	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.2	135.9	-179.2	-54.7	-179.9	0	0	0	109.2	L334 E338 V343 T356 E357 C358	L334-I345 HydrophobicContact CD1-CD1 4.05Å; L334-I345 HydrophobicContact CD2-CD1 3.81Å; L334-I345 HydrophobicContact CG-CD1 3.52Å; L334-I345 HydrophobicContact CG-CG1 4.44Å; E338-I345 HydrophobicContact CB-CD1 3.81Å; E338-I345 HydrophobicContact CG-CD1 4.07Å; V343-I345 HydrophobicContact CG1-CG1 3.89Å; I345-T356 HydrophobicContact CG2-CG2 3.73Å; I345-E357 CarbonylContact C-O 3.43Å; I345-E357 WeakPolarHBondContact CA-O 3.39Å; I345-C358 HydrophobicContact CG1-CB 4.46Å
346	H	95.2	Very high	94	Very high	87 Å²	87	79.1 Å²	79.1	40%	0.403	41%	0.409	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.5	129.7	169.8	-58.1	-66.7	0	0	0	108.5	Y318 T344 E357	Y318-H346 AromaticContact CE1-CD2 3.49Å; Y318-H346 VanDerWaalsContact CE1-CD2 3.49Å; Y318-H346 WeakPolarHBondContact CE1-CD2 3.5Å; Y318-H346 AromaticContact CE1-NE2 3.65Å; Y318-H346 AromaticContact CZ-NE2 3.82Å; Y318-H346 PolarHBondContact OH-NE2 3.43Å; T344-H346 WeakPolarHBondContact CG2-NE2 3.45Å; H346-E357 HydrophobicContact CB-CB 4.38Å; H346-E357 PolarHBondContact N-O 3.34Å; H346-E357 PolarHBondContact O-N 3.3Å
347	Q	93.8	Very high	93.9	Very high	162 Å²	162	79.5 Å²	79.5	76%	0.757	41%	0.406	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-102.5	134.7	173	-68.4	179.6	-20	0	0	108.2
348	S	92.7	Very high	93.9	Very high	41 Å²	41	78.9 Å²	78.9	29%	0.287	40%	0.402	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.9	129.9	176.8	65.5	0	0	0	0	109.2	F355	S348-F355 PolarHBondContact N-O 2.83Å; S348-F355 PolarHBondContact O-N 3.47Å
349	D	91.9	Very high	93.9	Very high	126 Å²	126	74.6 Å²	74.6	67%	0.674	38%	0.381	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-100.5	131	170.2	-161.6	7.9	0	0	0	109.2
350	T	89.9	Confident	93.9	Very high	56 Å²	56	70.4 Å²	70.4	34%	0.344	35%	0.352	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-139	167.6	-176.1	56.9	0	0	0	0	108.9	D352 G353 F355	T350-D352 PolarHBondContact O-N 3.17Å; T350-G353 PolarHBondContact N-O 3.48Å; T350-G353 WeakPolarHBondContact O-CA 3.4Å; T350-G353 PolarHBondContact O-N 3.01Å; T350-G353 PolarHBondContact OG1-O 2.95Å; T350-G353 VanDerWaalsContact OG1-O 3.06Å; T350-F355 WeakPolarHBondContact OG1-CD2 3.42Å; T350-F355 VanDerWaalsContact OG1-CE2 3.25Å; T350-F355 WeakPolarHBondContact OG1-CE2 3.15Å
351	E	86.9	Confident	94	Very high	209 Å²	209	65.2 Å²	65.2	98%	0.977	33%	0.325	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.6	-28.1	177.8	-63	-177.4	178.9	0	0	113	G353	E351-G353 VanDerWaalsContact C-N 3.27Å; E351-G353 PolarHBondContact O-N 2.92Å
352	D	83.9	Confident	94.1	Very high	123 Å²	123	55.8 Å²	55.8	66%	0.658	29%	0.29	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.5	0.1	177.5	-67.6	-44.7	0	0	0	114.8	K322 T350 F355	K322-D352 PolarHBondContact NZ-O 3.35Å; T350-D352 PolarHBondContact O-N 3.17Å; D352-F355 HydrophobicContact CB-CE2 3.94Å; D352-F355 HydrophobicContact CB-CZ 4.15Å
353	G	90.3	Very high	94.2	Very high	29 Å²	29	53.4 Å²	53.4	30%	0.299	28%	0.278	S	S	.	.	E	Extended strand (participates in β ladder)	trans	110.4	-173.6	178.8	0	0	0	0	0	114.9	T350 E351 F355	T350-G353 PolarHBondContact N-O 3.48Å; T350-G353 WeakPolarHBondContact O-CA 3.4Å; T350-G353 PolarHBondContact O-N 3.01Å; T350-G353 PolarHBondContact OG1-O 2.95Å; T350-G353 VanDerWaalsContact OG1-O 3.06Å; E351-G353 VanDerWaalsContact C-N 3.27Å; E351-G353 PolarHBondContact O-N 2.92Å; G353-F355 WeakPolarHBondContact O-CD2 3.48Å; G353-F355 WeakPolarHBondContact O-CE2 3.42Å
354	E	93.1	Very high	94.4	Very high	102 Å²	102	53.3 Å²	53.3	48%	0.477	28%	0.277	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-74.9	125.6	178.3	-66.1	174.1	-176.3	0	0	112.1	T323	T323-E354 PolarHBondContact N-O 2.85Å; T323-E354 PolarHBondContact OG1-O 3.07Å
355	F	95.6	Very high	94.5	Very high	30 Å²	30	51.8 Å²	51.8	13%	0.132	27%	0.267	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.2	144.4	174.6	-68.4	-94.6	0	0	0	111.6	K320 F321 K322 T323 S348 T350 D352 G353	K320-F355 HydrophobicContact CD-CD1 4.43Å; K320-F355 VanDerWaalsContact CE-CB 3.5Å; K320-F355 VanDerWaalsContact CE-CG 3.46Å; K320-F355 HydrophobicContact CG-CB 4.21Å; K320-F355 HydrophobicContact CG-CD1 4.05Å; K320-F355 HydrophobicContact CG-CG 4.44Å; F321-F355 WeakPolarHBondContact O-CA 3.4Å; K322-F355 HydrophobicContact CD-CE1 4.48Å; K322-F355 HydrophobicContact CD-CZ 4.48Å; K322-F355 HydrophobicContact CG-CD1 4.01Å; K322-F355 HydrophobicContact CG-CE1 3.49Å; K322-F355 VanDerWaalsContact CG-CE1 3.49Å; K322-F355 HydrophobicContact CG-CZ 3.9Å; T323-F355 VanDerWaalsContact OG1-C 3.31Å; S348-F355 PolarHBondContact N-O 2.83Å; S348-F355 PolarHBondContact O-N 3.47Å; T350-F355 WeakPolarHBondContact OG1-CD2 3.42Å; T350-F355 VanDerWaalsContact OG1-CE2 3.25Å; T350-F355 WeakPolarHBondContact OG1-CE2 3.15Å; D352-F355 HydrophobicContact CB-CE2 3.94Å; D352-F355 HydrophobicContact CB-CZ 4.15Å; G353-F355 WeakPolarHBondContact O-CD2 3.48Å; G353-F355 WeakPolarHBondContact O-CE2 3.42Å
356	T	95.6	Very high	94.6	Very high	6 Å²	6	51 Å²	51	4%	0.037	26%	0.264	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-110.9	129.4	167.7	-62.7	0	0	0	0	108.1	F321 T323 L334 I345	F321-T356 HydrophobicContact CE2-CG2 4.13Å; F321-T356 HydrophobicContact CZ-CG2 4.04Å; F321-T356 PolarHBondContact N-O 2.96Å; F321-T356 PolarHBondContact O-N 3.29Å; T323-T356 PolarHBondContact OG1-N 2.97Å; T323-T356 PolarHBondContact OG1-OG1 3.11Å; L334-T356 HydrophobicContact CD2-CG2 3.96Å; I345-T356 HydrophobicContact CG2-CG2 3.73Å
357	E	95.7	Very high	94.8	Very high	65 Å²	65	47.5 Å²	47.5	30%	0.304	25%	0.248	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-115.8	110.7	174	-178.2	170	-141	0	0	108.8	Y318 S319 K320 I345 H346	Y318-E357 VanDerWaalsContact CB-CG 3.46Å; Y318-E357 WeakPolarHBondContact CB-OE1 3.31Å; Y318-E357 HydrophobicContact CD1-CG 3.87Å; Y318-E357 HydrophobicContact CG-CG 3.96Å; S319-E357 WeakPolarHBondContact O-CA 3.21Å; K320-E357 HydrophobicContact CB-CB 4.33Å; K320-E357 HydrophobicContact CB-CG 4.3Å; K320-E357 HydrophobicContact CG-CB 4.46Å; I345-E357 CarbonylContact C-O 3.43Å; I345-E357 WeakPolarHBondContact CA-O 3.39Å; H346-E357 HydrophobicContact CB-CB 4.38Å; H346-E357 PolarHBondContact N-O 3.34Å; H346-E357 PolarHBondContact O-N 3.3Å
358	C	96.4	Very high	95	Very high	0 Å²	0	40 Å²	40	0%	0	21%	0.213	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-107.5	148.1	176.9	76.6	0	0	0	0	110.7	Y318 S319 L334 V343 T344 I345	Y318-C358 CarbonylContact C-O 3.59Å; Y318-C358 VanDerWaalsContact CA-O 3.29Å; Y318-C358 WeakPolarHBondContact CA-O 3.46Å; S319-C358 PolarHBondContact N-O 2.92Å; S319-C358 PolarHBondContact O-N 2.91Å; S319-C358 VanDerWaalsContact O-N 3.08Å; L334-C358 HydrophobicContact CD1-CB 3.77Å; V343-C358 HydrophobicContact CG1-CB 3.95Å; T344-C358 WeakPolarHBondContact O-CA 3.27Å; I345-C358 HydrophobicContact CG1-CB 4.46Å
359	N	95.9	Very high	95.3	Very high	0 Å²	0	40.8 Å²	40.8	0%	0	21%	0.211	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-58.8	151.5	172	79.5	22.9	0	0	0	110.8	Y288 M316 Y318 T344 M361	Y288-N359 PolarHBondContact OH-OD1 2.95Å; M316-N359 HydrophobicContact SD-CB 4.39Å; Y318-N359 HydrophobicContact CD1-CB 4.1Å; Y318-N359 HydrophobicContact CE1-CB 4.03Å; T344-N359 PolarHBondContact N-ND2 3.19Å; T344-N359 PolarHBondContact O-N 3.12Å; N359-M361 PolarHBondContact O-N 3.37Å
360	N	98.3	Very high	95.5	Very high	3 Å²	3	39.8 Å²	39.8	2%	0.016	20%	0.204	C	C	.	.			trans	-69.9	126.8	173.3	-85.1	-52.5	0	0	0	110	Q292 P300 R303 S317 T362 N365	Q292-N360 PolarHBondContact NE2-OD1 2.88Å; P300-N360 WeakPolarHBondContact CD-OD1 3.24Å; P300-N360 WeakPolarHBondContact CG-OD1 3.44Å; R303-N360 HydrophobicContact CB-CB 4.16Å; R303-N360 HydrophobicContact CG-CB 4.49Å; S317-N360 PolarHBondContact O-N 3.5Å; S317-N360 PolarHBondContact OG-ND2 3.33Å; N360-T362 VanDerWaalsContact C-N 3.3Å; N360-T362 PolarHBondContact O-N 3.27Å; N360-N365 VanDerWaalsContact O-CB 3.22Å; N360-N365 WeakPolarHBondContact O-CB 3.47Å; N360-N365 PolarHBondContact O-ND2 3.4Å
361	M	98.4	Very high	95.9	Very high	3 Å²	3	43.2 Å²	43.2	2%	0.015	22%	0.215	C	C	.	.			trans	-78.7	77.8	-174.5	-62.7	171.1	162.7	0	0	110.6	Y288 S289 P291 Q292 I297 R303 L334 A337 V343 N359	Y288-M361 HydrophobicContact CD1-CB 4.23Å; Y288-M361 HydrophobicContact CD2-CB 4.41Å; Y288-M361 VanDerWaalsContact CE1-CA 3.44Å; Y288-M361 HydrophobicContact CE1-CB 3.98Å; Y288-M361 HydrophobicContact CE2-CB 4.15Å; Y288-M361 HydrophobicContact CE2-CG 4.19Å; Y288-M361 HydrophobicContact CG-CB 4.44Å; Y288-M361 WeakPolarHBondContact O-CB 3.41Å; S289-M361 VanDerWaalsContact CA-O 3.31Å; S289-M361 WeakPolarHBondContact CA-O 3.33Å; S289-M361 PolarHBondContact OG-O 3.05Å; P291-M361 HydrophobicContact CB-SD 3.97Å; P291-M361 HydrophobicContact CG-SD 4.06Å; Q292-M361 HydrophobicContact CG-CB 4.31Å; Q292-M361 HydrophobicContact CG-CG 4.4Å; Q292-M361 HydrophobicContact CG-SD 4.08Å; I297-M361 HydrophobicContact CD1-CE 3.5Å; I297-M361 VanDerWaalsContact CD1-CE 3.5Å; I297-M361 HydrophobicContact CD1-SD 4.09Å; R303-M361 PolarHBondContact NH1-O 3.05Å; R303-M361 VanDerWaalsContact NH1-O 3.07Å; L334-M361 HydrophobicContact CD1-CE 4.11Å; A337-M361 HydrophobicContact CB-CE 4.47Å; V343-M361 HydrophobicContact CG2-CE 3.58Å; V343-M361 HydrophobicContact CG2-CG 4.27Å; N359-M361 PolarHBondContact O-N 3.37Å
362	T	98.6	Very high	96.5	Very high	7 Å²	7	34.4 Å²	34.4	4%	0.043	18%	0.181	C	C	.	.	S	Bend	trans	-134.8	151.8	172.7	74.2	0	0	0	0	110.2	N285 Y288 R303 N360 I364 N365 L366	N285-T362 WeakPolarHBondContact OD1-CA 3.2Å; Y288-T362 VanDerWaalsContact CE1-N 3.28Å; Y288-T362 WeakPolarHBondContact CE1-O 3.5Å; R303-T362 HydrophobicContact CB-CG2 3.79Å; N360-T362 VanDerWaalsContact C-N 3.3Å; N360-T362 PolarHBondContact O-N 3.27Å; T362-I364 PolarHBondContact O-N 3.38Å; T362-N365 PolarHBondContact O-N 2.85Å; T362-N365 VanDerWaalsContact O-N 3.14Å; T362-N365 PolarHBondContact OG1-N 2.8Å; T362-N365 PolarHBondContact OG1-ND2 3.03Å; T362-L366 PolarHBondContact O-N 2.99Å
363	L	98.7	Very high	97.2	Very high	7 Å²	7	31.6 Å²	31.6	4%	0.037	17%	0.169	C	C	.	.	H	α-helix	trans	-58	-33.9	177.8	178	58.7	0	0	0	111.7	L187 P281 F284 N285 L366 L367 L383 L386	L187-L363 HydrophobicContact CD1-CB 4.12Å; L187-L363 HydrophobicContact CD1-CD2 4.42Å; L187-L363 HydrophobicContact CD2-CD2 4.4Å; P281-L363 HydrophobicContact CB-CD2 3.96Å; F284-L363 HydrophobicContact CD1-CB 4.48Å; F284-L363 HydrophobicContact CD1-CD1 3.84Å; F284-L363 HydrophobicContact CE1-CD1 3.85Å; N285-L363 HydrophobicContact CB-CB 3.93Å; N285-L363 PolarHBondContact OD1-N 3.43Å; L363-L366 PolarHBondContact O-N 2.93Å; L363-L367 HydrophobicContact CD1-CG 4.4Å; L363-L367 WeakPolarHBondContact O-CG 3.46Å; L363-L367 PolarHBondContact O-N 2.95Å; L363-L383 HydrophobicContact CD2-CD2 3.9Å; L363-L383 HydrophobicContact CG-CD2 3.9Å; L363-L386 HydrophobicContact CD1-CD2 4.24Å; L363-L386 HydrophobicContact CD2-CD2 4.08Å
364	I	98.7	Very high	97.6	Very high	4 Å²	4	31.5 Å²	31.5	2%	0.021	16%	0.161	C	C	.	.	H	α-helix	trans	-59.9	-51.1	176	-53.3	178.5	0	0	0	110.6	L187 A188 L193 P305 T362 L366 L367 L368 L379 L383	L187-I364 HydrophobicContact CD1-CG1 4.11Å; A188-I364 WeakPolarHBondContact O-CD1 3.11Å; L193-I364 HydrophobicContact CD2-CD1 3.81Å; L193-I364 HydrophobicContact CD2-CG1 4.31Å; P305-I364 HydrophobicContact CG-CG2 4.01Å; T362-I364 PolarHBondContact O-N 3.38Å; I364-L366 VanDerWaalsContact C-N 3.33Å; I364-L366 PolarHBondContact O-N 3.23Å; I364-L367 PolarHBondContact O-N 2.96Å; I364-L368 WeakPolarHBondContact O-CG 3.23Å; I364-L368 PolarHBondContact O-N 3.27Å; I364-L379 HydrophobicContact CG2-CD2 3.64Å; I364-L379 HydrophobicContact CG2-CG 4.36Å; I364-L383 HydrophobicContact CG1-CD1 3.97Å
365	N	98.6	Very high	97.8	Very high	0 Å²	0	29.3 Å²	29.3	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-68	-33.3	178	-74.6	-66.8	0	0	0	112.2	R303 M316 S317 N360 T362 L368 K369	R303-N365 PolarHBondContact O-ND2 3.4Å; M316-N365 WeakPolarHBondContact CA-OD1 3.46Å; S317-N365 PolarHBondContact N-OD1 3.29Å; S317-N365 PolarHBondContact OG-OD1 2.99Å; N360-N365 VanDerWaalsContact O-CB 3.22Å; N360-N365 WeakPolarHBondContact O-CB 3.47Å; N360-N365 PolarHBondContact O-ND2 3.4Å; T362-N365 PolarHBondContact O-N 2.85Å; T362-N365 VanDerWaalsContact O-N 3.14Å; T362-N365 PolarHBondContact OG1-N 2.8Å; T362-N365 PolarHBondContact OG1-ND2 3.03Å; N365-L368 CarbonylContact O-C 3.53Å; N365-L368 PolarHBondContact O-N 2.99Å; N365-K369 WeakPolarHBondContact O-CB 3.47Å; N365-K369 PolarHBondContact O-N 3.48Å
366	L	98.6	Very high	98	Very high	12 Å²	12	28.1 Å²	28.1	6%	0.063	15%	0.146	C	C	.	.	H	α-helix	trans	-64.2	-39.8	175.8	-176.5	63.2	0	0	0	111.7	F284 Y288 T362 L363 I364 L368 K369 I370	F284-L366 HydrophobicContact CE1-CD2 3.55Å; F284-L366 HydrophobicContact CZ-CD2 3.57Å; Y288-L366 HydrophobicContact CE1-CB 4.09Å; T362-L366 PolarHBondContact O-N 2.99Å; L363-L366 PolarHBondContact O-N 2.93Å; I364-L366 VanDerWaalsContact C-N 3.33Å; I364-L366 PolarHBondContact O-N 3.23Å; L366-L368 VanDerWaalsContact C-N 3.35Å; L366-K369 HydrophobicContact CD1-CD 4.24Å; L366-K369 VanDerWaalsContact O-CB 3.31Å; L366-K369 WeakPolarHBondContact O-CB 3.2Å; L366-K369 PolarHBondContact O-N 2.89Å; L366-I370 HydrophobicContact CD1-CD1 4.33Å; L366-I370 HydrophobicContact CG-CD1 4.06Å; L366-I370 WeakPolarHBondContact O-CG1 3.1Å; L366-I370 PolarHBondContact O-N 3.36Å
367	L	98.6	Very high	98.1	Very high	13 Å²	13	33.5 Å²	33.5	7%	0.068	17%	0.165	C	C	.	.	H	α-helix	trans	-64.3	-40.3	173.6	-69.1	179.8	0	0	0	111.8	L363 I364 K369 I370 F371 L379 L382 L383	L363-L367 HydrophobicContact CD1-CG 4.4Å; L363-L367 WeakPolarHBondContact O-CG 3.46Å; L363-L367 PolarHBondContact O-N 2.95Å; I364-L367 PolarHBondContact O-N 2.96Å; L367-K369 VanDerWaalsContact C-N 3.27Å; L367-K369 PolarHBondContact O-N 3.25Å; L367-I370 PolarHBondContact O-N 3.29Å; L367-F371 HydrophobicContact CD2-CD2 4.22Å; L367-F371 HydrophobicContact CD2-CE2 3.93Å; L367-F371 WeakPolarHBondContact O-CB 3.17Å; L367-F371 WeakPolarHBondContact O-CD2 3.42Å; L367-F371 PolarHBondContact O-N 3.43Å; L367-L379 HydrophobicContact CB-CD1 4.21Å; L367-L379 HydrophobicContact CD1-CD1 4.45Å; L367-L382 HydrophobicContact CD1-CD2 4.23Å; L367-L382 HydrophobicContact CD1-CG 4.31Å; L367-L383 HydrophobicContact CD1-CD1 4.39Å; L367-L383 HydrophobicContact CD1-CD2 3.41Å; L367-L383 VanDerWaalsContact CD1-CD2 3.41Å; L367-L383 HydrophobicContact CD1-CG 3.55Å
368	L	98.6	Very high	98.3	Very high	4 Å²	4	33.8 Å²	33.8	2%	0.021	17%	0.169	C	C	.	.	H	α-helix	trans	-66.6	-29.3	174.2	-65.3	175.8	0	0	0	112.6	P305 L314 M316 I364 N365 L366 G372 I374 L379	P305-L368 HydrophobicContact CB-CD1 3.5Å; P305-L368 HydrophobicContact CG-CD1 4.29Å; L314-L368 HydrophobicContact CB-CD1 4.31Å; L314-L368 WeakPolarHBondContact O-CD2 3.42Å; M316-L368 HydrophobicContact CG-CB 3.78Å; I364-L368 WeakPolarHBondContact O-CG 3.23Å; I364-L368 PolarHBondContact O-N 3.27Å; N365-L368 CarbonylContact O-C 3.53Å; N365-L368 PolarHBondContact O-N 2.99Å; L366-L368 VanDerWaalsContact C-N 3.35Å; L368-G372 WeakPolarHBondContact CD2-O 3.39Å; L368-G372 CarbonylContact O-C 3.52Å; L368-G372 WeakPolarHBondContact O-CA 3.35Å; L368-G372 PolarHBondContact O-N 3.27Å; L368-I374 HydrophobicContact CD2-CB 3.91Å; L368-I374 HydrophobicContact CD2-CD1 4.37Å; L368-I374 HydrophobicContact CD2-CG1 4.13Å; L368-L379 HydrophobicContact CD1-CD2 4.12Å; L368-L379 HydrophobicContact CD2-CD1 4.09Å; L368-L379 HydrophobicContact CD2-CD2 3.97Å; L368-L379 HydrophobicContact CG-CD1 4.37Å; L368-L379 HydrophobicContact CG-CD2 4.11Å
369	K	98.1	Very high	98.4	Very high	58 Å²	58	33.8 Å²	33.8	25%	0.252	17%	0.169	S	C	.	.	H	α-helix	trans	-66.1	-42.3	170.8	-173.9	-175.9	176	-68.5	0	111.7	M316 R341 T344 N365 L366 L367	M316-K369 HydrophobicContact CE-CB 4.46Å; M316-K369 VanDerWaalsContact SD-CA 3.57Å; M316-K369 HydrophobicContact SD-CB 3.52Å; M316-K369 VanDerWaalsContact SD-CB 3.52Å; M316-K369 HydrophobicContact SD-CG 4.02Å; R341-K369 VanDerWaalsContact O-CE 3.26Å; R341-K369 WeakPolarHBondContact O-CE 3.24Å; R341-K369 PolarHBondContact O-NZ 2.95Å; T344-K369 VanDerWaalsContact OG1-CE 3.27Å; T344-K369 WeakPolarHBondContact OG1-CE 3.44Å; N365-K369 WeakPolarHBondContact O-CB 3.47Å; N365-K369 PolarHBondContact O-N 3.48Å; L366-K369 HydrophobicContact CD1-CD 4.24Å; L366-K369 VanDerWaalsContact O-CB 3.31Å; L366-K369 WeakPolarHBondContact O-CB 3.2Å; L366-K369 PolarHBondContact O-N 2.89Å; L367-K369 VanDerWaalsContact C-N 3.27Å; L367-K369 PolarHBondContact O-N 3.25Å
370	I	97.9	Very high	98.5	Very high	104 Å²	104	33.8 Å²	33.8	53%	0.533	17%	0.169	S	C	.	.	H	α-helix	trans	-78	-45.3	-175.1	-67.3	166.8	0	0	0	111.4	L366 L367	L366-I370 HydrophobicContact CD1-CD1 4.33Å; L366-I370 HydrophobicContact CG-CD1 4.06Å; L366-I370 WeakPolarHBondContact O-CG1 3.1Å; L366-I370 PolarHBondContact O-N 3.36Å; L367-I370 PolarHBondContact O-N 3.29Å
371	F	98.3	Very high	98.5	Very high	128 Å²	128	37.4 Å²	37.4	56%	0.561	19%	0.188	S	C	*	.	H	α-helix	trans	-104.8	-4.1	-171.1	-65	-71	0	0	0	113.9	L367 I374 L382	L367-F371 HydrophobicContact CD2-CD2 4.22Å; L367-F371 HydrophobicContact CD2-CE2 3.93Å; L367-F371 WeakPolarHBondContact O-CB 3.17Å; L367-F371 WeakPolarHBondContact O-CD2 3.42Å; L367-F371 PolarHBondContact O-N 3.43Å; F371-I374 HydrophobicContact CB-CD1 3.78Å; F371-L382 HydrophobicContact CD2-CD2 3.93Å; F371-L382 HydrophobicContact CE2-CD2 4.16Å
372	G	98.1	Very high	98.6	Very high	25 Å²	25	39.5 Å²	39.5	26%	0.258	20%	0.199	S	C	.	.			trans	77.8	-164.6	-175.1	0	0	0	0	0	113.3	L368 I374	L368-G372 WeakPolarHBondContact CD2-O 3.39Å; L368-G372 CarbonylContact O-C 3.52Å; L368-G372 WeakPolarHBondContact O-CA 3.35Å; L368-G372 PolarHBondContact O-N 3.27Å; G372-I374 PolarHBondContact O-N 2.86Å
373	P	98.5	Very high	98.6	Very high	64 Å²	64	39.4 Å²	39.4	42%	0.416	20%	0.198	S	C	.	.	S	Bend	trans	-66	127.8	-177.8	-21.4	33.2	0	0	0	112.8	K313 L314 E315	K313-P373 HydrophobicContact CB-CB 4.11Å; K313-P373 HydrophobicContact CD-CB 4.24Å; K313-P373 WeakPolarHBondContact CD-O 3.2Å; L314-P373 VanDerWaalsContact O-CA 3.29Å; L314-P373 WeakPolarHBondContact O-CA 3.37Å; E315-P373 HydrophobicContact CG-CB 3.92Å; E315-P373 HydrophobicContact CG-CG 3.96Å
374	I	98.6	Very high	98.6	Very high	27 Å²	27	40 Å²	40	14%	0.138	20%	0.202	C	C	.	.	B	Isolated β-bridge	trans	-125.8	140.6	-177.5	-60.4	172.9	0	0	0	109.8	L314 L368 F371 G372 N378 L379 L382	L314-I374 WeakPolarHBondContact CB-O 3.18Å; L314-I374 PolarHBondContact N-O 3.32Å; L314-I374 PolarHBondContact O-N 3.49Å; L368-I374 HydrophobicContact CD2-CB 3.91Å; L368-I374 HydrophobicContact CD2-CD1 4.37Å; L368-I374 HydrophobicContact CD2-CG1 4.13Å; F371-I374 HydrophobicContact CB-CD1 3.78Å; G372-I374 PolarHBondContact O-N 2.86Å; I374-N378 HydrophobicContact CG2-CB 3.77Å; I374-L379 HydrophobicContact CB-CB 4.29Å; I374-L379 HydrophobicContact CB-CD1 4.47Å; I374-L379 HydrophobicContact CD1-CD1 4.14Å; I374-L379 HydrophobicContact CG2-CB 3.88Å; I374-L382 HydrophobicContact CD1-CD2 3.9Å
375	H	98.6	Very high	98.6	Very high	56 Å²	56	44.1 Å²	44.1	26%	0.259	22%	0.223	S	C	.	.			trans	-66.3	140.6	173	-179	70.2	0	0	0	111.2	Y244 G312 K313 R377 N378 L379	Y244-H375 AromaticContact CE1-NE2 3.7Å; Y244-H375 AromaticContact CZ-CE1 3.79Å; Y244-H375 AromaticContact CZ-NE2 3.47Å; Y244-H375 PolarHBondContact OH-CE1 3.32Å; Y244-H375 VanDerWaalsContact OH-CE1 3.25Å; Y244-H375 PolarHBondContact OH-NE2 2.69Å; G312-H375 PolarHBondContact O-ND1 3.24Å; K313-H375 HydrophobicContact CG-CB 4.44Å; H375-R377 PolarHBondContact O-N 3.05Å; H375-N378 WeakPolarHBondContact O-CA 3.48Å; H375-N378 WeakPolarHBondContact O-CB 3.44Å; H375-N378 PolarHBondContact O-N 3.44Å; H375-L379 PolarHBondContact O-N 3.49Å
376	E	98.7	Very high	98.6	Very high	5 Å²	5	47.2 Å²	47.2	2%	0.023	24%	0.239	C	C	.	.	H	α-helix	trans	-48.3	-51.7	-170.9	-175.1	176.7	-163.3	0	0	114	I190 N191 Y244 L314 N378 L379 T380	I190-E376 WeakPolarHBondContact CA-OE1 3.39Å; I190-E376 HydrophobicContact CB-CG 4.1Å; I190-E376 HydrophobicContact CG2-CG 4.48Å; N191-E376 WeakPolarHBondContact CB-OE1 3.26Å; N191-E376 PolarHBondContact N-OE1 3.29Å; N191-E376 PolarHBondContact ND2-OE1 2.79Å; N191-E376 PolarHBondContact ND2-OE2 2.81Å; Y244-E376 HydrophobicContact CD2-CB 4.18Å; Y244-E376 HydrophobicContact CD2-CG 4.1Å; Y244-E376 WeakPolarHBondContact CD2-OE2 3.31Å; Y244-E376 HydrophobicContact CE2-CB 4Å; Y244-E376 HydrophobicContact CE2-CG 4.32Å; Y244-E376 WeakPolarHBondContact CE2-OE2 3.49Å; L314-E376 HydrophobicContact CD1-CB 3.69Å; L314-E376 HydrophobicContact CD1-CG 3.85Å; L314-E376 HydrophobicContact CG-CB 4.18Å; E376-N378 VanDerWaalsContact C-N 3.27Å; E376-N378 PolarHBondContact O-N 3.01Å; E376-L379 WeakPolarHBondContact O-CB 3.4Å; E376-L379 PolarHBondContact O-N 3.35Å; E376-L379 VanDerWaalsContact O-N 3.1Å; E376-T380 PolarHBondContact O-N 3.27Å; E376-T380 PolarHBondContact O-OG1 3.4Å
377	R	98.7	Very high	98.6	Very high	118 Å²	118	46.8 Å²	46.8	45%	0.445	24%	0.237	S	C	.	.	H	α-helix	trans	-54.8	-43	178	-172.3	-172.6	71.6	175.1	1.4	112.7	W243 Y244 H375 L381	W243-R377 HydrophobicContact CZ2-CG 4.43Å; Y244-R377 HydrophobicContact CD1-CB 3.79Å; Y244-R377 HydrophobicContact CD1-CG 4.16Å; Y244-R377 HydrophobicContact CD2-CB 4.42Å; Y244-R377 HydrophobicContact CE1-CB 4.34Å; Y244-R377 HydrophobicContact CG-CB 3.84Å; Y244-R377 HydrophobicContact CG-CG 4.31Å; H375-R377 PolarHBondContact O-N 3.05Å; R377-L381 HydrophobicContact CG-CD1 4.31Å; R377-L381 WeakPolarHBondContact O-CG 3.49Å; R377-L381 PolarHBondContact O-N 3.48Å
378	N	98.8	Very high	98.6	Very high	71 Å²	71	50.4 Å²	50.4	38%	0.38	26%	0.255	S	S	.	.	H	α-helix	trans	-74.5	-31.5	-177.4	-63.4	-6	0	0	0	111	I374 H375 E376 L381 L382	I374-N378 HydrophobicContact CG2-CB 3.77Å; H375-N378 WeakPolarHBondContact O-CA 3.48Å; H375-N378 WeakPolarHBondContact O-CB 3.44Å; H375-N378 PolarHBondContact O-N 3.44Å; E376-N378 VanDerWaalsContact C-N 3.27Å; E376-N378 PolarHBondContact O-N 3.01Å; N378-L381 PolarHBondContact O-N 3.48Å; N378-L382 VanDerWaalsContact O-CB 3.32Å; N378-L382 WeakPolarHBondContact O-CB 3.34Å; N378-L382 PolarHBondContact O-N 2.9Å
379	L	98.8	Very high	98.6	Very high	0 Å²	0	55.1 Å²	55.1	0%	0	28%	0.28	C	S	.	.	H	α-helix	trans	-67.7	-43.2	174.5	-174.6	60.5	0	0	0	111.1	I190 L314 I364 L367 L368 I374 H375 E376 L382 L383	I190-L379 HydrophobicContact CD1-CB 4.32Å; I190-L379 HydrophobicContact CD1-CD2 4.18Å; I190-L379 HydrophobicContact CD1-CG 3.95Å; L314-L379 HydrophobicContact CB-CD2 4.47Å; L314-L379 HydrophobicContact CD1-CD2 3.93Å; I364-L379 HydrophobicContact CG2-CD2 3.64Å; I364-L379 HydrophobicContact CG2-CG 4.36Å; L367-L379 HydrophobicContact CB-CD1 4.21Å; L367-L379 HydrophobicContact CD1-CD1 4.45Å; L368-L379 HydrophobicContact CD1-CD2 4.12Å; L368-L379 HydrophobicContact CD2-CD1 4.09Å; L368-L379 HydrophobicContact CD2-CD2 3.97Å; L368-L379 HydrophobicContact CG-CD1 4.37Å; L368-L379 HydrophobicContact CG-CD2 4.11Å; I374-L379 HydrophobicContact CB-CB 4.29Å; I374-L379 HydrophobicContact CB-CD1 4.47Å; I374-L379 HydrophobicContact CD1-CD1 4.14Å; I374-L379 HydrophobicContact CG2-CB 3.88Å; H375-L379 PolarHBondContact O-N 3.49Å; E376-L379 WeakPolarHBondContact O-CB 3.4Å; E376-L379 PolarHBondContact O-N 3.35Å; E376-L379 VanDerWaalsContact O-N 3.1Å; L379-L382 PolarHBondContact O-N 3.04Å; L379-L383 HydrophobicContact CG-CD1 4.4Å; L379-L383 PolarHBondContact O-N 3.27Å
380	T	98.9	Very high	98.6	Very high	0 Å²	0	52.7 Å²	52.7	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-58.7	-50.9	171.4	-56.3	0	0	0	0	110.5	I190 N191 L193 W243 E376 L382 L383 L384	I190-T380 WeakPolarHBondContact CD1-OG1 3.22Å; I190-T380 WeakPolarHBondContact CG1-OG1 3.35Å; N191-T380 WeakPolarHBondContact O-CG2 3.4Å; N191-T380 PolarHBondContact O-OG1 2.87Å; L193-T380 HydrophobicContact CB-CG2 4.3Å; W243-T380 HydrophobicContact CH2-CG2 4.16Å; W243-T380 HydrophobicContact CZ3-CG2 3.93Å; E376-T380 PolarHBondContact O-N 3.27Å; E376-T380 PolarHBondContact O-OG1 3.4Å; T380-L382 VanDerWaalsContact C-N 3.28Å; T380-L382 PolarHBondContact O-N 3.46Å; T380-L383 PolarHBondContact O-N 3.06Å; T380-L383 VanDerWaalsContact O-N 3.14Å; T380-L384 HydrophobicContact CG2-CD1 4.24Å; T380-L384 HydrophobicContact CG2-CG 4.36Å; T380-L384 WeakPolarHBondContact O-CG 3.46Å; T380-L384 PolarHBondContact O-N 2.95Å
381	L	98.8	Very high	98.6	Very high	80 Å²	80	48 Å²	48	42%	0.419	25%	0.248	S	C	.	.	H	α-helix	trans	-58.6	-38.2	178.2	-76.2	168.7	0	0	0	112.9	W243 R377 N378 L384 L385	W243-L381 HydrophobicContact CH2-CD2 3.61Å; W243-L381 HydrophobicContact CH2-CG 3.91Å; W243-L381 HydrophobicContact CZ2-CD1 4.44Å; W243-L381 HydrophobicContact CZ2-CD2 3.74Å; W243-L381 HydrophobicContact CZ2-CG 3.92Å; R377-L381 HydrophobicContact CG-CD1 4.31Å; R377-L381 WeakPolarHBondContact O-CG 3.49Å; R377-L381 PolarHBondContact O-N 3.48Å; N378-L381 PolarHBondContact O-N 3.48Å; L381-L384 PolarHBondContact O-N 3.28Å; L381-L385 WeakPolarHBondContact O-CB 3.33Å; L381-L385 PolarHBondContact O-N 3.26Å
382	L	98.8	Very high	98.6	Very high	46 Å²	46	44.1 Å²	44.1	24%	0.241	24%	0.24	C	C	.	.	H	α-helix	trans	-65.1	-41.7	176.4	180	61.6	0	0	0	111.9	L367 F371 I374 N378 L379 T380 L385 L386	L367-L382 HydrophobicContact CD1-CD2 4.23Å; L367-L382 HydrophobicContact CD1-CG 4.31Å; F371-L382 HydrophobicContact CD2-CD2 3.93Å; F371-L382 HydrophobicContact CE2-CD2 4.16Å; I374-L382 HydrophobicContact CD1-CD2 3.9Å; N378-L382 VanDerWaalsContact O-CB 3.32Å; N378-L382 WeakPolarHBondContact O-CB 3.34Å; N378-L382 PolarHBondContact O-N 2.9Å; L379-L382 PolarHBondContact O-N 3.04Å; T380-L382 VanDerWaalsContact C-N 3.28Å; T380-L382 PolarHBondContact O-N 3.46Å; L382-L385 PolarHBondContact O-N 3.04Å; L382-L386 WeakPolarHBondContact O-CB 3.42Å; L382-L386 PolarHBondContact O-N 2.92Å
383	L	98.8	Very high	98.5	Very high	6 Å²	6	47.9 Å²	47.9	3%	0.031	25%	0.249	C	C	.	.	H	α-helix	trans	-66.2	-39.1	175	-78.9	156.9	0	0	0	112	I190 L193 L363 I364 L367 L379 T380 L386 Q387	I190-L383 HydrophobicContact CD1-CD1 3.71Å; L193-L383 HydrophobicContact CD1-CB 3.69Å; L193-L383 HydrophobicContact CD1-CD1 3.97Å; L193-L383 HydrophobicContact CD1-CG 4.38Å; L193-L383 HydrophobicContact CD2-CD1 3.96Å; L363-L383 HydrophobicContact CD2-CD2 3.9Å; L363-L383 HydrophobicContact CG-CD2 3.9Å; I364-L383 HydrophobicContact CG1-CD1 3.97Å; L367-L383 HydrophobicContact CD1-CD1 4.39Å; L367-L383 HydrophobicContact CD1-CD2 3.41Å; L367-L383 VanDerWaalsContact CD1-CD2 3.41Å; L367-L383 HydrophobicContact CD1-CG 3.55Å; L379-L383 HydrophobicContact CG-CD1 4.4Å; L379-L383 PolarHBondContact O-N 3.27Å; T380-L383 PolarHBondContact O-N 3.06Å; T380-L383 VanDerWaalsContact O-N 3.14Å; L383-L386 WeakPolarHBondContact O-CB 3.36Å; L383-L386 PolarHBondContact O-N 3.14Å; L383-Q387 WeakPolarHBondContact O-CB 3.29Å; L383-Q387 PolarHBondContact O-N 2.88Å
384	L	98.9	Very high	98.4	Very high	20 Å²	20	44.9 Å²	44.9	11%	0.105	23%	0.23	C	C	.	.	H	α-helix	trans	-66.8	-37.8	173.9	-63	-176.1	0	0	0	111.8	Q197 V200 W243 T380 L381 Q387 I388	Q197-L384 HydrophobicContact CB-CD2 4.28Å; Q197-L384 VanDerWaalsContact N-CD2 3.3Å; V200-L384 HydrophobicContact CG2-CD2 4.46Å; W243-L384 HydrophobicContact CH2-CD1 4.01Å; W243-L384 HydrophobicContact CZ3-CD1 3.81Å; T380-L384 HydrophobicContact CG2-CD1 4.24Å; T380-L384 HydrophobicContact CG2-CG 4.36Å; T380-L384 WeakPolarHBondContact O-CG 3.46Å; T380-L384 PolarHBondContact O-N 2.95Å; L381-L384 PolarHBondContact O-N 3.28Å; L384-Q387 WeakPolarHBondContact O-CB 3.43Å; L384-Q387 PolarHBondContact O-N 3.34Å; L384-I388 VanDerWaalsContact O-CG1 3.32Å; L384-I388 WeakPolarHBondContact O-CG1 3.44Å; L384-I388 PolarHBondContact O-N 2.82Å
385	L	98.8	Very high	98.3	Very high	90 Å²	90	45.6 Å²	45.6	47%	0.471	23%	0.232	S	C	.	.	H	α-helix	trans	-63.1	-44.1	172.4	179.4	62.3	0	0	0	111	L381 L382 Q387 I388 L389	L381-L385 WeakPolarHBondContact O-CB 3.33Å; L381-L385 PolarHBondContact O-N 3.26Å; L382-L385 PolarHBondContact O-N 3.04Å; L385-Q387 VanDerWaalsContact C-N 3.26Å; L385-Q387 PolarHBondContact O-N 3.28Å; L385-I388 PolarHBondContact O-N 2.92Å; L385-L389 HydrophobicContact CD1-CG 4.49Å; L385-L389 HydrophobicContact CG-CD1 4.32Å; L385-L389 WeakPolarHBondContact O-CG 3.47Å; L385-L389 PolarHBondContact O-N 3.46Å
386	L	98.6	Very high	98.1	Very high	65 Å²	65	45.8 Å²	45.8	34%	0.34	24%	0.239	S	C	.	.	H	α-helix	trans	-59.9	-38.3	174.6	-177.7	63.5	0	0	0	111.6	L363 L382 L383 L389 G390	L363-L386 HydrophobicContact CD1-CD2 4.24Å; L363-L386 HydrophobicContact CD2-CD2 4.08Å; L382-L386 WeakPolarHBondContact O-CB 3.42Å; L382-L386 PolarHBondContact O-N 2.92Å; L383-L386 WeakPolarHBondContact O-CB 3.36Å; L383-L386 PolarHBondContact O-N 3.14Å; L386-L389 PolarHBondContact O-N 3.35Å; L386-G390 PolarHBondContact O-N 3.19Å
387	Q	98.8	Very high	97.8	Very high	2 Å²	2	46.9 Å²	46.9	1%	0.009	25%	0.245	C	C	.	.	H	α-helix	trans	-63.1	-45.2	173.6	-173.1	63.9	57.2	0	0	112.1	V200 I201 F278 P281 L383 L384 L385 L389 G390 S391	V200-Q387 HydrophobicContact CB-CB 4.47Å; V200-Q387 HydrophobicContact CB-CG 3.74Å; V200-Q387 HydrophobicContact CG1-CB 4.18Å; V200-Q387 HydrophobicContact CG1-CG 3.57Å; V200-Q387 HydrophobicContact CG2-CG 4.45Å; I201-Q387 HydrophobicContact CG1-CG 4.49Å; F278-Q387 PolarHBondContact O-NE2 3.24Å; P281-Q387 HydrophobicContact CG-CB 4.47Å; P281-Q387 VanDerWaalsContact CG-OE1 3.23Å; L383-Q387 WeakPolarHBondContact O-CB 3.29Å; L383-Q387 PolarHBondContact O-N 2.88Å; L384-Q387 WeakPolarHBondContact O-CB 3.43Å; L384-Q387 PolarHBondContact O-N 3.34Å; L385-Q387 VanDerWaalsContact C-N 3.26Å; L385-Q387 PolarHBondContact O-N 3.28Å; Q387-L389 PolarHBondContact O-N 3.47Å; Q387-G390 PolarHBondContact O-N 2.04Å; Q387-S391 PolarHBondContact O-N 2.85Å; Q387-S391 PolarHBondContact O-OG 3.45Å
388	I	98.8	Very high	97.4	Very high	90 Å²	90	45.4 Å²	45.4	46%	0.462	24%	0.24	S	C	.	.	H	α-helix	trans	-62	-43.4	175.8	-67.9	165	0	0	0	110.8	V200 L384 L385 G390 S391 A392	V200-I388 HydrophobicContact CG1-CB 4.49Å; V200-I388 HydrophobicContact CG1-CG1 3.65Å; V200-I388 HydrophobicContact CG2-CG1 4.07Å; L384-I388 VanDerWaalsContact O-CG1 3.32Å; L384-I388 WeakPolarHBondContact O-CG1 3.44Å; L384-I388 PolarHBondContact O-N 2.82Å; L385-I388 PolarHBondContact O-N 2.92Å; I388-G390 VanDerWaalsContact C-N 3.33Å; I388-G390 PolarHBondContact O-N 2.96Å; I388-S391 WeakPolarHBondContact O-CB 3.5Å; I388-S391 PolarHBondContact O-N 2.88Å; I388-A392 PolarHBondContact O-N 3.28Å
389	L	98.5	Very high	97	Very high	102 Å²	102	45.8 Å²	45.8	53%	0.534	24%	0.236	S	C	.	.	H	α-helix	trans	-62.6	-40.3	176.3	-69.6	173.7	0	0	0	111.6	L385 L386 Q387 S391 A392 F393	L385-L389 HydrophobicContact CD1-CG 4.49Å; L385-L389 HydrophobicContact CG-CD1 4.32Å; L385-L389 WeakPolarHBondContact O-CG 3.47Å; L385-L389 PolarHBondContact O-N 3.46Å; L386-L389 PolarHBondContact O-N 3.35Å; Q387-L389 PolarHBondContact O-N 3.47Å; L389-S391 VanDerWaalsContact C-N 3.33Å; L389-S391 PolarHBondContact O-N 3.45Å; L389-A392 PolarHBondContact O-N 3.32Å; L389-F393 WeakPolarHBondContact O-CB 3.43Å; L389-F393 PolarHBondContact O-N 3Å
390	G	98.3	Very high	96.5	Very high	8 Å²	8	52.9 Å²	52.9	8%	0.082	27%	0.27	C	S	.	.	H	α-helix	trans	-60.1	-41.2	172.3	0	0	0	0	0	112.6	L386 Q387 I388 F393 T394	L386-G390 PolarHBondContact O-N 3.19Å; Q387-G390 PolarHBondContact O-N 2.04Å; I388-G390 VanDerWaalsContact C-N 3.33Å; I388-G390 PolarHBondContact O-N 2.96Å; G390-F393 PolarHBondContact O-N 2.97Å; G390-T394 WeakPolarHBondContact O-CB 3.49Å; G390-T394 PolarHBondContact O-N 3.14Å; G390-T394 PolarHBondContact O-OG1 2.96Å
391	S	98.1	Very high	95.9	Very high	4 Å²	4	56 Å²	56	3%	0.028	29%	0.286	C	S	.	.	H	α-helix	trans	-66.3	-43.5	174.1	-64.9	0	0	0	0	112.9	S204 Q387 I388 L389 F393 T394 F395	S204-S391 VanDerWaalsContact OG-CB 3.23Å; S204-S391 WeakPolarHBondContact OG-CB 3.28Å; S204-S391 PolarHBondContact OG-OG 3.29Å; Q387-S391 PolarHBondContact O-N 2.85Å; Q387-S391 PolarHBondContact O-OG 3.45Å; I388-S391 WeakPolarHBondContact O-CB 3.5Å; I388-S391 PolarHBondContact O-N 2.88Å; L389-S391 VanDerWaalsContact C-N 3.33Å; L389-S391 PolarHBondContact O-N 3.45Å; S391-F393 VanDerWaalsContact C-N 3.3Å; S391-F393 PolarHBondContact O-N 3.34Å; S391-T394 WeakPolarHBondContact O-CB 3.1Å; S391-T394 PolarHBondContact O-N 3Å; S391-T394 VanDerWaalsContact O-N 3.15Å; S391-F395 WeakPolarHBondContact O-CD2 3.42Å; S391-F395 PolarHBondContact O-N 3.42Å
392	A	97.9	Very high	95.2	Very high	48 Å²	48	53.2 Å²	53.2	40%	0.397	27%	0.272	S	S	.	.	H	α-helix	trans	-62.1	-39	175.9	0	0	0	0	0	112.1	I388 L389 F395 S396	I388-A392 PolarHBondContact O-N 3.28Å; L389-A392 PolarHBondContact O-N 3.32Å; A392-F395 PolarHBondContact O-N 2.86Å; A392-S396 PolarHBondContact O-N 3.07Å; A392-S396 PolarHBondContact O-OG 3.29Å
393	F	96.9	Very high	94.4	Very high	104 Å²	104	59.6 Å²	59.6	46%	0.456	29%	0.293	S	S	.	.	H	α-helix	trans	-65.5	-40.5	173.2	-177.9	-115.1	0	0	0	111.7	M280 L389 G390 S391 F395 S396 I397	M280-F393 HydrophobicContact CE-CD1 3.65Å; M280-F393 HydrophobicContact CE-CE1 3.89Å; M280-F393 HydrophobicContact SD-CD1 4.08Å; M280-F393 HydrophobicContact SD-CE1 4.47Å; L389-F393 WeakPolarHBondContact O-CB 3.43Å; L389-F393 PolarHBondContact O-N 3Å; G390-F393 PolarHBondContact O-N 2.97Å; S391-F393 VanDerWaalsContact C-N 3.3Å; S391-F393 PolarHBondContact O-N 3.34Å; F393-F395 PolarHBondContact O-N 3.44Å; F393-S396 WeakPolarHBondContact O-CB 3.48Å; F393-S396 PolarHBondContact O-N 2.99Å; F393-I397 HydrophobicContact CD1-CD1 3.78Å; F393-I397 HydrophobicContact CE1-CD1 3.33Å; F393-I397 HydrophobicContact CE1-CG1 4.22Å; F393-I397 HydrophobicContact CE2-CD1 4.36Å; F393-I397 HydrophobicContact CE2-CG1 4.42Å; F393-I397 HydrophobicContact CG-CD1 4.47Å; F393-I397 HydrophobicContact CZ-CD1 3.65Å; F393-I397 HydrophobicContact CZ-CG1 4.14Å; F393-I397 WeakPolarHBondContact O-CG1 3.33Å; F393-I397 PolarHBondContact O-N 3.13Å
394	T	96	Very high	93.6	Very high	0 Å²	0	64.8 Å²	64.8	0%	0	32%	0.32	C	S	.	.	H	α-helix	trans	-60.3	-45.6	174.1	-61.6	0	0	0	0	111.8	T274 L277 F278 G390 S391 S396 I397 R398	T274-T394 HydrophobicContact CG2-CG2 4.24Å; L277-T394 VanDerWaalsContact C-OG1 3.26Å; L277-T394 HydrophobicContact CB-CG2 3.43Å; L277-T394 VanDerWaalsContact CB-CG2 3.43Å; L277-T394 WeakPolarHBondContact CB-OG1 3.34Å; L277-T394 HydrophobicContact CD1-CG2 4.15Å; L277-T394 HydrophobicContact CG-CG2 4.45Å; L277-T394 PolarHBondContact O-OG1 3.4Å; F278-T394 HydrophobicContact CD1-CG2 3.67Å; F278-T394 HydrophobicContact CE1-CG2 3.47Å; F278-T394 VanDerWaalsContact CE1-CG2 3.47Å; F278-T394 HydrophobicContact CG-CG2 4.26Å; F278-T394 HydrophobicContact CZ-CG2 3.93Å; G390-T394 WeakPolarHBondContact O-CB 3.49Å; G390-T394 PolarHBondContact O-N 3.14Å; G390-T394 PolarHBondContact O-OG1 2.96Å; S391-T394 WeakPolarHBondContact O-CB 3.1Å; S391-T394 PolarHBondContact O-N 3Å; S391-T394 VanDerWaalsContact O-N 3.15Å; T394-S396 VanDerWaalsContact C-N 3.33Å; T394-S396 PolarHBondContact O-N 3.25Å; T394-I397 PolarHBondContact O-N 3.35Å; T394-I397 VanDerWaalsContact O-N 3.16Å; T394-R398 WeakPolarHBondContact O-CB 3.04Å; T394-R398 PolarHBondContact O-N 3.42Å
395	F	96.3	Very high	92.7	Very high	43 Å²	43	67.8 Å²	67.8	19%	0.189	33%	0.332	C	S	.	.	H	α-helix	trans	-61.7	-40.9	175.2	-76.7	-57.3	0	0	0	112.3	S204 V207 F208 F278 S391 A392 F393 I397 R398 Y399	S204-F395 WeakPolarHBondContact O-CZ 3.35Å; V207-F395 HydrophobicContact CB-CZ 4.01Å; V207-F395 HydrophobicContact CG1-CE1 4.37Å; V207-F395 HydrophobicContact CG1-CE2 4.31Å; V207-F395 HydrophobicContact CG1-CZ 3.75Å; F208-F395 HydrophobicContact CB-CE1 3.82Å; F208-F395 HydrophobicContact CB-CZ 4.14Å; F208-F395 HydrophobicContact CD2-CE1 4.4Å; F278-F395 HydrophobicContact CE1-CD2 4.26Å; F278-F395 HydrophobicContact CE1-CE1 4.39Å; F278-F395 AromaticContact CE1-CE2 3.97Å; F278-F395 HydrophobicContact CE1-CE2 3.97Å; F278-F395 HydrophobicContact CE1-CZ 4.06Å; F278-F395 HydrophobicContact CZ-CD1 4.37Å; F278-F395 AromaticContact CZ-CE1 3.89Å; F278-F395 HydrophobicContact CZ-CE1 3.89Å; F278-F395 HydrophobicContact CZ-CE2 4.18Å; F278-F395 AromaticContact CZ-CZ 3.78Å; F278-F395 HydrophobicContact CZ-CZ 3.78Å; S391-F395 WeakPolarHBondContact O-CD2 3.42Å; S391-F395 PolarHBondContact O-N 3.42Å; A392-F395 PolarHBondContact O-N 2.86Å; F393-F395 PolarHBondContact O-N 3.44Å; F395-I397 VanDerWaalsContact C-N 3.33Å; F395-I397 PolarHBondContact O-N 3.49Å; F395-R398 PolarHBondContact O-N 2.93Å; F395-Y399 HydrophobicContact CB-CD2 4.41Å; F395-Y399 HydrophobicContact CD1-CD2 4.03Å; F395-Y399 AromaticContact CD1-CE2 3.56Å; F395-Y399 HydrophobicContact CD1-CE2 3.56Å; F395-Y399 HydrophobicContact CE1-CE2 4.1Å; F395-Y399 WeakPolarHBondContact O-CD2 3.35Å; F395-Y399 PolarHBondContact O-N 3.09Å
396	S	94.6	Very high	91.9	Very high	59 Å²	59	66.1 Å²	66.1	41%	0.413	32%	0.32	S	S	.	.	H	α-helix	trans	-59.8	-43.4	172.7	-58.3	0	0	0	0	111.7	A392 F393 T394 Q400 L401	A392-S396 PolarHBondContact O-N 3.07Å; A392-S396 PolarHBondContact O-OG 3.29Å; F393-S396 WeakPolarHBondContact O-CB 3.48Å; F393-S396 PolarHBondContact O-N 2.99Å; T394-S396 VanDerWaalsContact C-N 3.33Å; T394-S396 PolarHBondContact O-N 3.25Å; S396-Q400 WeakPolarHBondContact O-CA 3.35Å; S396-Q400 VanDerWaalsContact O-CB 3.3Å; S396-Q400 WeakPolarHBondContact O-CB 3.47Å; S396-Q400 PolarHBondContact O-N 3.06Å; S396-L401 PolarHBondContact O-N 3.17Å
397	I	91.9	Very high	90.8	Very high	29 Å²	29	68.1 Å²	68.1	15%	0.149	33%	0.331	C	S	.	.	I	π-helix	trans	-61.4	-50.4	175.6	-71.1	169.8	0	0	0	110.7	L277 F393 T394 F395 L401 V402	L277-I397 HydrophobicContact CD1-CG2 4.24Å; F393-I397 HydrophobicContact CD1-CD1 3.78Å; F393-I397 HydrophobicContact CE1-CD1 3.33Å; F393-I397 HydrophobicContact CE1-CG1 4.22Å; F393-I397 HydrophobicContact CE2-CD1 4.36Å; F393-I397 HydrophobicContact CE2-CG1 4.42Å; F393-I397 HydrophobicContact CG-CD1 4.47Å; F393-I397 HydrophobicContact CZ-CD1 3.65Å; F393-I397 HydrophobicContact CZ-CG1 4.14Å; F393-I397 WeakPolarHBondContact O-CG1 3.33Å; F393-I397 PolarHBondContact O-N 3.13Å; T394-I397 PolarHBondContact O-N 3.35Å; T394-I397 VanDerWaalsContact O-N 3.16Å; F395-I397 VanDerWaalsContact C-N 3.33Å; F395-I397 PolarHBondContact O-N 3.49Å; I397-L401 HydrophobicContact CG1-CD1 4.17Å; I397-L401 CarbonylContact O-C 2.98Å; I397-L401 VanDerWaalsContact O-C 3.31Å; I397-L401 WeakPolarHBondContact O-CA 3.31Å; I397-L401 PolarHBondContact O-N 2.88Å; I397-L401 VanDerWaalsContact O-N 3.13Å; I397-V402 PolarHBondContact O-N 2.95Å
398	R	91.1	Very high	89.2	Confident	86 Å²	86	74.3 Å²	74.3	33%	0.325	37%	0.369	S	S	.	.	I	π-helix	trans	-66.1	-42.1	-174	176.3	59.4	178.4	-175.8	-0.5	112.8	F208 E212 T394 F395 V402	F208-R398 HydrophobicContact CE2-CG 4.19Å; E212-R398 IonicContact OE1-NE 3.59Å; E212-R398 IonicContact OE1-NH2 2.66Å; E212-R398 IonicContact OE2-CZ 3.99Å; E212-R398 IonicContact OE2-NH2 2.97Å; E212-R398 PolarHBondContact OE2-NH2 2.89Å; T394-R398 WeakPolarHBondContact O-CB 3.04Å; T394-R398 PolarHBondContact O-N 3.42Å; F395-R398 PolarHBondContact O-N 2.93Å; R398-V402 VanDerWaalsContact O-CB 3.28Å; R398-V402 WeakPolarHBondContact O-CB 3.47Å; R398-V402 WeakPolarHBondContact O-CG1 3.43Å
399	Y	90.6	Very high	88.8	Confident	79 Å²	79	73.5 Å²	73.5	31%	0.31	36%	0.364	S	S	.	.	I	π-helix	trans	-100	-19.6	-171.5	-66.2	-59.7	0	0	0	114.6	F208 V211 E212 F395	F208-Y399 WeakPolarHBondContact CD2-OH 3.29Å; V211-Y399 HydrophobicContact CG1-CE1 3.9Å; V211-Y399 HydrophobicContact CG1-CE2 4.23Å; V211-Y399 VanDerWaalsContact CG1-OH 3.25Å; V211-Y399 WeakPolarHBondContact CG1-OH 3.4Å; E212-Y399 WeakPolarHBondContact OE1-CE1 3.45Å; E212-Y399 VanDerWaalsContact OE1-CZ 3.27Å; E212-Y399 PolarHBondContact OE1-OH 3.21Å; F395-Y399 HydrophobicContact CB-CD2 4.41Å; F395-Y399 HydrophobicContact CD1-CD2 4.03Å; F395-Y399 AromaticContact CD1-CE2 3.56Å; F395-Y399 HydrophobicContact CD1-CE2 3.56Å; F395-Y399 HydrophobicContact CE1-CE2 4.1Å; F395-Y399 WeakPolarHBondContact O-CD2 3.35Å; F395-Y399 PolarHBondContact O-N 3.09Å
400	Q	88.1	Confident	88.3	Confident	150 Å²	150	72 Å²	72	70%	0.701	36%	0.355	S	S	*	.	I	π-helix	trans	-116.4	-40.3	-179.1	-53.7	-59.7	-29.3	0	0	112.5	S396	S396-Q400 WeakPolarHBondContact O-CA 3.35Å; S396-Q400 VanDerWaalsContact O-CB 3.3Å; S396-Q400 WeakPolarHBondContact O-CB 3.47Å; S396-Q400 PolarHBondContact O-N 3.06Å
401	L	84.7	Confident	87.7	Confident	66 Å²	66	75.6 Å²	75.6	35%	0.346	37%	0.37	S	S	.	.	I	π-helix	trans	-100.7	-1.2	-171.8	-51.8	176.2	0	0	0	114	S396 I397 R403 L404 F405	S396-L401 PolarHBondContact O-N 3.17Å; I397-L401 HydrophobicContact CG1-CD1 4.17Å; I397-L401 CarbonylContact O-C 2.98Å; I397-L401 VanDerWaalsContact O-C 3.31Å; I397-L401 WeakPolarHBondContact O-CA 3.31Å; I397-L401 PolarHBondContact O-N 2.88Å; I397-L401 VanDerWaalsContact O-N 3.13Å; L401-R403 PolarHBondContact O-N 2.61Å; L401-R403 VanDerWaalsContact O-N 3.12Å; L401-L404 HydrophobicContact CB-CD1 4.17Å; L401-L404 HydrophobicContact CD2-CD1 4Å; L401-L404 VanDerWaalsContact O-CB 3.26Å; L401-L404 WeakPolarHBondContact O-CB 3.47Å; L401-L404 PolarHBondContact O-N 3.06Å; L401-F405 WeakPolarHBondContact O-CD2 3.35Å
402	V	84.6	Confident	87.1	Confident	21 Å²	21	79.8 Å²	79.8	13%	0.127	39%	0.39	C	S	.	.	H	α-helix	trans	-58.6	-32.1	-175.8	71.5	0	0	0	0	112.2	I397 R398 L404 F405 Y406 V408	I397-V402 PolarHBondContact O-N 2.95Å; R398-V402 VanDerWaalsContact O-CB 3.28Å; R398-V402 WeakPolarHBondContact O-CB 3.47Å; R398-V402 WeakPolarHBondContact O-CG1 3.43Å; V402-L404 PolarHBondContact O-N 3.22Å; V402-F405 PolarHBondContact O-N 2.93Å; V402-Y406 HydrophobicContact CG2-CD2 4.04Å; V402-Y406 PolarHBondContact O-N 3.19Å; V402-V408 HydrophobicContact CG1-CB 4.1Å; V402-V408 HydrophobicContact CG1-CG1 4.36Å; V402-V408 HydrophobicContact CG1-CG2 4.09Å; V402-V408 HydrophobicContact CG2-CG2 3.83Å
403	R	82.6	Confident	86.4	Confident	180 Å²	180	81.8 Å²	81.8	68%	0.679	39%	0.39	S	S	*	.	H	α-helix	trans	-62.3	-22	175.3	-68.7	-176.5	173.6	166.3	4.6	113.9	K153 L401 F405 Y406 V408	K153-R403 PolarHBondContact NZ-O 3.04Å; L401-R403 PolarHBondContact O-N 2.61Å; L401-R403 VanDerWaalsContact O-N 3.12Å; R403-F405 VanDerWaalsContact C-N 3.29Å; R403-Y406 CarbonylContact C-O 3.48Å; R403-Y406 WeakPolarHBondContact CA-O 3.45Å; R403-V408 PolarHBondContact NE-O 3.25Å
404	L	80.7	Confident	85.7	Confident	114 Å²	114	80.3 Å²	80.3	60%	0.597	39%	0.386	S	S	*	.	H	α-helix	trans	-73.5	-23.4	173.1	-61.6	179.2	0	0	0	112.3	K153 L401 V402	K153-L404 WeakPolarHBondContact CD-O 3.38Å; L401-L404 HydrophobicContact CB-CD1 4.17Å; L401-L404 HydrophobicContact CD2-CD1 4Å; L401-L404 VanDerWaalsContact O-CB 3.26Å; L401-L404 WeakPolarHBondContact O-CB 3.47Å; L401-L404 PolarHBondContact O-N 3.06Å; V402-L404 PolarHBondContact O-N 3.22Å
405	F	80.9	Confident	85	Confident	83 Å²	83	86 Å²	86	36%	0.364	41%	0.413	S	S	.	.	H	α-helix	trans	-111.5	-30	-174.1	-62.9	-79.1	0	0	0	113.3	P152 K153 L401 V402 R403	P152-F405 CarbonylContact C-O 3.43Å; P152-F405 WeakPolarHBondContact CA-O 3.16Å; K153-F405 WeakPolarHBondContact CG-O 3.37Å; K153-F405 PolarHBondContact N-O 2.94Å; L401-F405 WeakPolarHBondContact O-CD2 3.35Å; V402-F405 PolarHBondContact O-N 2.93Å; R403-F405 VanDerWaalsContact C-N 3.29Å
406	Y	83.1	Confident	84.1	Confident	55 Å²	55	89.3 Å²	89.3	22%	0.216	43%	0.431	C	S	.	.	S	Bend	trans	-136.2	161.3	-175	-63.4	-71.4	0	0	0	110.5	V150 P152 K153 K273 V402 R403 V408	V150-Y406 HydrophobicContact CB-CD1 4.41Å; V150-Y406 HydrophobicContact CB-CE1 4.16Å; V150-Y406 HydrophobicContact CG1-CD1 3.72Å; V150-Y406 HydrophobicContact CG1-CE1 3.86Å; P152-Y406 HydrophobicContact CG-CE1 4.43Å; K153-Y406 WeakPolarHBondContact CE-O 3.27Å; K153-Y406 PolarHBondContact NZ-O 3.44Å; K273-Y406 PolarHBondContact NZ-OH 3.19Å; V402-Y406 HydrophobicContact CG2-CD2 4.04Å; V402-Y406 PolarHBondContact O-N 3.19Å; R403-Y406 CarbonylContact C-O 3.48Å; R403-Y406 WeakPolarHBondContact CA-O 3.45Å; Y406-V408 PolarHBondContact O-N 2.85Å
407	D	75.3	Confident	83.2	Confident	108 Å²	108	91.8 Å²	91.8	58%	0.578	43%	0.432	S	S	*	.			trans	-91.5	100.6	170.5	-55.6	-50.8	0	0	0	106	K153 R156	K153-D407 WeakPolarHBondContact CE-OD1 3.37Å; K153-D407 IonicContact NZ-OD1 3.92Å; K153-D407 PolarHBondContact NZ-OD1 3.21Å; R156-D407 IonicContact CZ-OD2 3.2Å; R156-D407 IonicContact NH1-OD1 3.8Å; R156-D407 IonicContact NH1-OD2 2.64Å; R156-D407 PolarHBondContact NH1-OD2 3.2Å; R156-D407 IonicContact NH2-OD2 2.86Å; R156-D407 PolarHBondContact NH2-OD2 2.98Å
408	V	65.3	Low	82.5	Confident	131 Å²	131	97.5 Å²	97.5	79%	0.794	46%	0.458	S	S	*	.			trans	-128.7	0	-176.1	-169.5	0	0	0	0	109.3	V402 R403 Y406	V402-V408 HydrophobicContact CG1-CB 4.1Å; V402-V408 HydrophobicContact CG1-CG1 4.36Å; V402-V408 HydrophobicContact CG1-CG2 4.09Å; V402-V408 HydrophobicContact CG2-CG2 3.83Å; R403-V408 PolarHBondContact NE-O 3.25Å; Y406-V408 PolarHBondContact O-N 2.85Å

Retrieved 408 of 408 residues in 85.5 ms (Link to these results)

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