A0A096N5A6_PAPAN Loading...

Serine incorporator 1

Enhances the incorporation of serine into phosphatidylserine and sphingolipids.

AlphaFold DB (Q9NRX5), UniProt , Accession A0A096N5A6, Species PAPAN (Papio anubis, Olive baboon), Gene SERINC1, Length 453 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	39.3	Very low	44.7	Very low	250 Å²	250	125.6 Å²	125.6	100%	1.232	78%	0.783	S	S	*	*				0	46.9	0	-65.1	168.3	68.2	0	0	111
2	G	35.7	Very low	45.2	Very low	73 Å²	73	118.9 Å²	118.9	75%	0.753	74%	0.744	S	S	*	*			trans	-121.4	29.6	-163.1	0	0	0	0	0	115.6
3	S	41.7	Very low	45.9	Very low	116 Å²	116	117.6 Å²	117.6	81%	0.811	72%	0.717	S	S	*	*	S	Bend	trans	-127.1	6.7	-168.7	-2.9	0	0	0	0	116.1
4	V	44.9	Very low	46.5	Very low	138 Å²	138	116.4 Å²	116.4	84%	0.836	70%	0.702	S	S	*	*	S	Bend	trans	-107.6	-6	-175.1	-176.3	0	0	0	0	114	G6	V4-G6 PolarHBondContact O-N 3.16Å
5	L	46.5	Very low	47	Very low	182 Å²	182	114.7 Å²	114.7	95%	0.953	70%	0.695	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.6	11.8	-177.2	-70.4	169.6	0	0	0	115.3
6	G	44.1	Very low	47.5	Very low	73 Å²	73	110 Å²	110	75%	0.753	67%	0.668	S	S	*	*	T	Hydrogen-bonded Turn	trans	-102.3	-1.5	-168.2	0	0	0	0	0	118.2	V4	V4-G6 PolarHBondContact O-N 3.16Å
7	L	41.8	Very low	48	Very low	169 Å²	169	106.4 Å²	106.4	89%	0.885	64%	0.644	S	S	*	*			trans	-125.2	3.9	-165.8	-85.5	161.9	0	0	0	117.6	S9	L7-S9 PolarHBondContact O-N 3.49Å
8	C	45.3	Very low	48.2	Very low	69 Å²	69	104.1 Å²	104.1	47%	0.466	63%	0.632	S	S	.	*			trans	-90.6	93.5	172.7	-72.6	0	0	0	0	110.8
9	S	49.6	Very low	48.5	Very low	85 Å²	85	99.9 Å²	99.9	59%	0.594	61%	0.612	S	S	*	*			trans	-51.2	136.9	170	-176.1	0	0	0	0	110.7	L7 A11 S12	L7-S9 PolarHBondContact O-N 3.49Å; S9-A11 PolarHBondContact O-N 3.1Å; S9-S12 PolarHBondContact O-N 2.97Å; S9-S12 PolarHBondContact O-OG 2.96Å
10	M	50.8	Low	48.7	Very low	163 Å²	163	99 Å²	99	80%	0.803	61%	0.61	S	S	*	*	G	3₁₀ helix	trans	-48.3	-27.9	179.2	-73	-85.1	-74.8	0	0	113.5	S12 W13	M10-S12 VanDerWaalsContact C-N 3.31Å; M10-S12 PolarHBondContact O-N 3.35Å; M10-W13 PolarHBondContact O-N 3.34Å
11	A	51.7	Low	49	Very low	64 Å²	64	95.5 Å²	95.5	53%	0.529	59%	0.591	S	S	.	*	G	3₁₀ helix	trans	-64.4	-28.5	177.1	0	0	0	0	0	114.2	S9 W13	S9-A11 PolarHBondContact O-N 3.1Å; A11-W13 VanDerWaalsContact C-N 3.3Å; A11-W13 PolarHBondContact O-N 3.07Å
12	S	51.5	Low	49.7	Very low	45 Å²	45	85.8 Å²	85.8	32%	0.315	55%	0.547	S	S	.	.	G	3₁₀ helix	trans	-78	-12.9	-177.6	68.4	0	0	0	0	113.9	S9 M10	S9-S12 PolarHBondContact O-N 2.97Å; S9-S12 PolarHBondContact O-OG 2.96Å; M10-S12 VanDerWaalsContact C-N 3.31Å; M10-S12 PolarHBondContact O-N 3.35Å
13	W	54.4	Low	50.6	Low	102 Å²	102	82.9 Å²	82.9	39%	0.386	52%	0.515	S	S	.	.	G	3₁₀ helix	trans	-83.6	-24.8	178.6	-64.7	69.7	0	0	0	112.2	M10 A11 C16 L17	M10-W13 PolarHBondContact O-N 3.34Å; A11-W13 VanDerWaalsContact C-N 3.3Å; A11-W13 PolarHBondContact O-N 3.07Å; W13-C16 PolarHBondContact O-N 2.85Å; W13-C16 VanDerWaalsContact O-N 3.14Å; W13-L17 HydrophobicContact CB-CD1 4.15Å; W13-L17 WeakPolarHBondContact O-CG 3.43Å; W13-L17 PolarHBondContact O-N 3.39Å
14	I	53.4	Low	51	Low	101 Å²	101	78.9 Å²	78.9	52%	0.518	48%	0.484	S	S	.	.	H	α-helix	trans	-57.8	-44.8	-173.4	-59.2	174.7	0	0	0	112.5	C16 L17 C18	I14-C16 VanDerWaalsContact C-N 3.3Å; I14-C16 PolarHBondContact O-N 2.84Å; I14-L17 PolarHBondContact O-N 3.17Å; I14-C18 WeakPolarHBondContact O-CB 3.21Å; I14-C18 PolarHBondContact O-N 3.44Å; I14-C18 VanDerWaalsContact O-N 3.07Å; I14-C18 PolarHBondContact O-SG 3.05Å
15	P	53.6	Low	51.4	Low	91 Å²	91	77.9 Å²	77.9	59%	0.591	47%	0.474	S	S	*	.	H	α-helix	trans	-64.7	-35.3	178.7	-20.3	33.2	0	0	0	112.7	C18 G19	P15-C18 PolarHBondContact O-N 3.38Å; P15-G19 PolarHBondContact O-N 3.27Å
16	C	55.5	Low	51.7	Low	39 Å²	39	69.7 Å²	69.7	26%	0.264	43%	0.431	S	S	.	.	H	α-helix	trans	-75.5	-28.9	-178.6	-57.3	0	0	0	0	112.9	W13 I14 C26	W13-C16 PolarHBondContact O-N 2.85Å; W13-C16 VanDerWaalsContact O-N 3.14Å; I14-C16 VanDerWaalsContact C-N 3.3Å; I14-C16 PolarHBondContact O-N 2.84Å; C16-C26 HydrophobicContact CB-CB 3.45Å; C16-C26 VanDerWaalsContact CB-CB 3.45Å; C16-C26 WeakPolarHBondContact CB-SG 3.08Å; C16-C26 VanDerWaalsContact SG-CA 3.57Å; C16-C26 WeakPolarHBondContact SG-CB 3.41Å; C16-C26 CovalentContact SG-SG 2Å; C16-C26 PolarHBondContact SG-SG 3.31Å
17	L	56.7	Low	52.1	Low	49 Å²	49	77.3 Å²	77.3	26%	0.257	44%	0.437	S	S	.	.	H	α-helix	trans	-75.2	-30.7	172.1	-72.6	164.3	0	0	0	112.1	W13 I14 W126 F127 F130	W13-L17 HydrophobicContact CB-CD1 4.15Å; W13-L17 WeakPolarHBondContact O-CG 3.43Å; W13-L17 PolarHBondContact O-N 3.39Å; I14-L17 PolarHBondContact O-N 3.17Å; L17-W126 HydrophobicContact CD2-CB 3.62Å; L17-W126 HydrophobicContact CD2-CG 4.07Å; L17-F127 WeakPolarHBondContact O-CB 3.28Å; L17-F127 PolarHBondContact O-N 2.92Å; L17-F130 HydrophobicContact CD2-CD2 4.46Å; L17-F130 HydrophobicContact CD2-CE2 3.67Å; L17-F130 HydrophobicContact CD2-CZ 4.5Å
18	C	51.6	Low	52.6	Low	65 Å²	65	71.2 Å²	71.2	44%	0.439	41%	0.408	S	S	.	.	H	α-helix	trans	-83.5	-12.1	-179.4	-65.4	0	0	0	0	114.6	I14 P15	I14-C18 WeakPolarHBondContact O-CB 3.21Å; I14-C18 PolarHBondContact O-N 3.44Å; I14-C18 VanDerWaalsContact O-N 3.07Å; I14-C18 PolarHBondContact O-SG 3.05Å; P15-C18 PolarHBondContact O-N 3.38Å
19	G	53.9	Low	53.1	Low	24 Å²	24	68.6 Å²	68.6	25%	0.247	39%	0.39	C	S	.	.	S	Bend	trans	-77.3	146.4	177.1	0	0	0	0	0	113.5	P15 A21	P15-G19 PolarHBondContact O-N 3.27Å; G19-A21 PolarHBondContact O-N 3.2Å
20	S	52.7	Low	53.4	Low	81 Å²	81	68 Å²	68	57%	0.566	39%	0.385	S	S	*	.	S	Bend	trans	-67.5	-16.1	161.7	50.2	0	0	0	0	112.4	F125	S20-F125 VanDerWaalsContact CB-CE1 3.49Å
21	A	53.5	Low	53.7	Low	27 Å²	27	65.2 Å²	65.2	22%	0.223	38%	0.381	C	S	.	.	S	Bend	trans	-60.5	134.2	175.9	0	0	0	0	0	111.4	G19 L25	G19-A21 PolarHBondContact O-N 3.2Å; A21-L25 HydrophobicContact CB-CB 4.02Å; A21-L25 HydrophobicContact CB-CD1 3.41Å; A21-L25 VanDerWaalsContact CB-CD1 3.41Å; A21-L25 HydrophobicContact CB-CG 4.22Å
22	P	54.8	Low	54.4	Low	46 Å²	46	63.6 Å²	63.6	30%	0.299	37%	0.371	S	S	.	.			trans	-54.3	159	161.5	-18.8	31.3	0	0	0	109.5	L24 L25	P22-L24 HydrophobicContact CB-CB 4.23Å; P22-L24 HydrophobicContact CB-CD1 3.74Å; P22-L24 HydrophobicContact CB-CG 3.77Å; P22-L24 HydrophobicContact CG-CD1 3.94Å; P22-L24 HydrophobicContact CG-CG 4.49Å; P22-L24 PolarHBondContact O-N 2.81Å; P22-L25 PolarHBondContact O-N 2.94Å
23	C	54.2	Low	55.6	Low	11 Å²	11	64.6 Å²	64.6	7%	0.074	37%	0.373	C	S	.	.	G	3₁₀ helix	trans	-48	-19.5	177.4	-79.4	0	0	0	0	114.3	L25 C26 C29 V37 I41	C23-L25 PolarHBondContact O-N 3.46Å; C23-C26 PolarHBondContact O-N 3.24Å; C23-C29 VanDerWaalsContact CB-SG 3.51Å; C23-C29 PolarHBondContact O-SG 3.31Å; C23-C29 VanDerWaalsContact O-SG 3.33Å; C23-V37 HydrophobicContact CB-CG1 4.24Å; C23-I41 VanDerWaalsContact SG-CD1 3.54Å
24	L	51.5	Low	56.8	Low	33 Å²	33	59.9 Å²	59.9	17%	0.173	36%	0.355	C	S	.	.	G	3₁₀ helix	trans	-37.6	-30.5	168.7	-61.4	175.1	0	0	0	116	P22 A374	P22-L24 HydrophobicContact CB-CB 4.23Å; P22-L24 HydrophobicContact CB-CD1 3.74Å; P22-L24 HydrophobicContact CB-CG 3.77Å; P22-L24 HydrophobicContact CG-CD1 3.94Å; P22-L24 HydrophobicContact CG-CG 4.49Å; P22-L24 PolarHBondContact O-N 2.81Å; L24-A374 HydrophobicContact CD2-CB 4.09Å; L24-A374 WeakPolarHBondContact CD2-O 3.31Å
25	L	51.3	Low	58.2	Low	117 Å²	117	55 Å²	55	61%	0.613	33%	0.33	S	S	*	.	G	3₁₀ helix	trans	-102.8	-0.5	-174.7	-74.9	164.3	0	0	0	114.7	A21 P22 C23	A21-L25 HydrophobicContact CB-CB 4.02Å; A21-L25 HydrophobicContact CB-CD1 3.41Å; A21-L25 VanDerWaalsContact CB-CD1 3.41Å; A21-L25 HydrophobicContact CB-CG 4.22Å; P22-L25 PolarHBondContact O-N 2.94Å; C23-L25 PolarHBondContact O-N 3.46Å
26	C	54.3	Low	59.6	Low	9 Å²	9	52 Å²	52	6%	0.061	31%	0.31	C	S	.	.			trans	-91.8	121	179.9	-163.1	0	0	0	0	111.8	C16 C23 C28 C29	C16-C26 HydrophobicContact CB-CB 3.45Å; C16-C26 VanDerWaalsContact CB-CB 3.45Å; C16-C26 WeakPolarHBondContact CB-SG 3.08Å; C16-C26 VanDerWaalsContact SG-CA 3.57Å; C16-C26 WeakPolarHBondContact SG-CB 3.41Å; C16-C26 CovalentContact SG-SG 2Å; C16-C26 PolarHBondContact SG-SG 3.31Å; C23-C26 PolarHBondContact O-N 3.24Å; C26-C28 PolarHBondContact O-N 3.25Å; C26-C29 HydrophobicContact CB-CB 4.39Å; C26-C29 PolarHBondContact O-N 3.08Å
27	R	52.1	Low	61	Low	234 Å²	234	50.6 Å²	50.6	88%	0.883	30%	0.3	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56	-19.6	174.4	-89.3	-174.7	171.8	-165.1	-2.6	114.7
28	C	52.4	Low	62.4	Low	40 Å²	40	48.3 Å²	48.3	27%	0.27	29%	0.288	S	S	.	.	T	Hydrogen-bonded Turn	trans	-98.5	0.7	-178.8	-63.6	0	0	0	0	113.5	C26	C26-C28 PolarHBondContact O-N 3.25Å
29	C	55	Low	64.2	Low	14 Å²	14	45.2 Å²	45.2	10%	0.095	27%	0.267	C	S	.	.	S	Bend	trans	-70.5	131.2	177.4	-81.7	0	0	0	0	109.9	C23 C26 S31	C23-C29 VanDerWaalsContact CB-SG 3.51Å; C23-C29 PolarHBondContact O-SG 3.31Å; C23-C29 VanDerWaalsContact O-SG 3.33Å; C26-C29 HydrophobicContact CB-CB 4.39Å; C26-C29 PolarHBondContact O-N 3.08Å; C29-S31 PolarHBondContact O-N 2.82Å
30	P	55.6	Low	65.9	Low	74 Å²	74	46.3 Å²	46.3	48%	0.481	27%	0.267	S	S	.	.			trans	-58.7	138.4	176	24.1	-31.7	0	0	0	109	G32 V37	P30-G32 PolarHBondContact O-N 3.38Å; P30-V37 HydrophobicContact CG-CG2 4.27Å
31	S	57.4	Low	67.7	Low	104 Å²	104	43.6 Å²	43.6	73%	0.727	25%	0.246	S	C	*	.	S	Bend	trans	-58.5	101.9	170.9	56.6	0	0	0	0	108.4	C29	C29-S31 PolarHBondContact O-N 2.82Å
32	G	67.2	Low	69.6	Low	30 Å²	30	42.3 Å²	42.3	31%	0.309	24%	0.236	S	C	.	.	S	Bend	trans	-168.9	166.4	-175.9	0	0	0	0	0	111.6	P30 N34 A374	P30-G32 PolarHBondContact O-N 3.38Å; G32-N34 PolarHBondContact O-N 3.07Å; G32-A374 WeakPolarHBondContact O-CA 3.49Å; G32-A374 VanDerWaalsContact O-CB 3.32Å; G32-A374 WeakPolarHBondContact O-CB 3.32Å
33	N	77	Confident	71.4	Confident	65 Å²	65	40.3 Å²	40.3	35%	0.348	22%	0.223	S	C	.	.	B	Isolated β-bridge	trans	-61.9	132.9	177.2	-68.6	-2.1	0	0	0	109.8	S35 T36 V37	N33-S35 PolarHBondContact O-N 3.32Å; N33-S35 VanDerWaalsContact O-N 3.15Å; N33-T36 PolarHBondContact O-N 3.22Å; N33-V37 PolarHBondContact O-N 3.24Å; N33-V37 VanDerWaalsContact O-N 3.13Å
34	N	79.3	Confident	73.2	Confident	3 Å²	3	43.7 Å²	43.7	2%	0.016	24%	0.239	C	C	.	.	H	α-helix	trans	-52.6	-38.7	179.2	-173.1	31.3	0	0	0	111.4	G32 T36 V37 T38 V375	G32-N34 PolarHBondContact O-N 3.07Å; N34-T36 VanDerWaalsContact C-N 3.32Å; N34-T36 PolarHBondContact O-N 3.14Å; N34-V37 PolarHBondContact O-N 3.29Å; N34-T38 WeakPolarHBondContact O-CB 3.35Å; N34-T38 PolarHBondContact O-N 2.86Å; N34-T38 PolarHBondContact O-OG1 3.43Å; N34-T38 VanDerWaalsContact O-OG1 3.13Å; N34-V375 PolarHBondContact N-O 3.17Å
35	S	82.3	Confident	75.2	Confident	0 Å²	0	43.4 Å²	43.4	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-61.9	-35	179.1	85.9	0	0	0	0	113.3	N33 R39 N377 E378 T383	N33-S35 PolarHBondContact O-N 3.32Å; N33-S35 VanDerWaalsContact O-N 3.15Å; S35-R39 VanDerWaalsContact O-CG 3.27Å; S35-R39 WeakPolarHBondContact O-CG 3.01Å; S35-R39 PolarHBondContact O-N 3.25Å; S35-R39 PolarHBondContact O-NE 3.29Å; S35-R39 VanDerWaalsContact O-NE 3.08Å; S35-N377 PolarHBondContact N-OD1 3.43Å; S35-N377 PolarHBondContact OG-ND2 3.31Å; S35-E378 WeakPolarHBondContact CB-OE1 3.23Å; S35-E378 WeakPolarHBondContact CB-OE2 3.38Å; S35-T383 PolarHBondContact OG-OG1 2.87Å
36	T	83.2	Confident	77.3	Confident	26 Å²	26	38 Å²	38	16%	0.16	21%	0.208	C	C	.	.	H	α-helix	trans	-77.6	-42	176.5	-57.7	0	0	0	0	111.6	N33 N34 R39 L40 S336	N33-T36 PolarHBondContact O-N 3.22Å; N34-T36 VanDerWaalsContact C-N 3.32Å; N34-T36 PolarHBondContact O-N 3.14Å; T36-R39 PolarHBondContact O-N 2.96Å; T36-R39 PolarHBondContact OG1-NH2 3.1Å; T36-L40 HydrophobicContact CG2-CD1 4.06Å; T36-L40 HydrophobicContact CG2-CG 4.46Å; T36-L40 WeakPolarHBondContact O-CB 3.04Å; T36-L40 WeakPolarHBondContact O-CG 3.36Å; T36-L40 PolarHBondContact O-N 3.5Å; T36-S336 PolarHBondContact OG1-OG 3Å
37	V	84	Confident	79.1	Confident	11 Å²	11	39.4 Å²	39.4	7%	0.067	22%	0.216	C	C	.	.	H	α-helix	trans	-61.6	-47.1	178.2	177.7	0	0	0	0	110.5	C23 P30 N33 N34 R39 L40 I41	C23-V37 HydrophobicContact CB-CG1 4.24Å; P30-V37 HydrophobicContact CG-CG2 4.27Å; N33-V37 PolarHBondContact O-N 3.24Å; N33-V37 VanDerWaalsContact O-N 3.13Å; N34-V37 PolarHBondContact O-N 3.29Å; V37-R39 PolarHBondContact O-N 3.14Å; V37-L40 PolarHBondContact O-N 3.1Å; V37-I41 HydrophobicContact CG1-CD1 3.95Å; V37-I41 HydrophobicContact CG1-CG1 4.5Å; V37-I41 WeakPolarHBondContact O-CG1 3.34Å; V37-I41 PolarHBondContact O-N 3.07Å
38	T	88	Confident	81.1	Confident	0 Å²	0	32.4 Å²	32.4	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-58.3	-47	177.7	-65.9	0	0	0	0	112	N34 L40 I41 Y42 H122 N123 W126	N34-T38 WeakPolarHBondContact O-CB 3.35Å; N34-T38 PolarHBondContact O-N 2.86Å; N34-T38 PolarHBondContact O-OG1 3.43Å; N34-T38 VanDerWaalsContact O-OG1 3.13Å; T38-L40 PolarHBondContact O-N 2.96Å; T38-I41 PolarHBondContact O-N 2.62Å; T38-Y42 HydrophobicContact CG2-CD2 3.92Å; T38-Y42 HydrophobicContact CG2-CE2 3.52Å; T38-Y42 WeakPolarHBondContact O-CD2 3.46Å; T38-Y42 PolarHBondContact O-N 3.04Å; T38-Y42 VanDerWaalsContact O-N 3.16Å; T38-H122 WeakPolarHBondContact CG2-O 3.3Å; T38-N123 PolarHBondContact OG1-OD1 2.88Å; T38-N123 VanDerWaalsContact OG1-OD1 3.05Å; T38-W126 HydrophobicContact CG2-CH2 3.89Å; T38-W126 HydrophobicContact CG2-CZ2 3.98Å
39	R	89.5	Confident	83.2	Confident	0 Å²	0	31 Å²	31	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-61.2	-44.1	177.1	-72	-178.9	-65.7	140	3.7	112.3	S35 T36 V37 I41 Y42 A43 S331 S332 I333 T335 S336 Y384 F389	S35-R39 VanDerWaalsContact O-CG 3.27Å; S35-R39 WeakPolarHBondContact O-CG 3.01Å; S35-R39 PolarHBondContact O-N 3.25Å; S35-R39 PolarHBondContact O-NE 3.29Å; S35-R39 VanDerWaalsContact O-NE 3.08Å; T36-R39 PolarHBondContact O-N 2.96Å; T36-R39 PolarHBondContact OG1-NH2 3.1Å; V37-R39 PolarHBondContact O-N 3.14Å; R39-I41 VanDerWaalsContact C-N 3.34Å; R39-I41 PolarHBondContact O-N 2.95Å; R39-Y42 PolarHBondContact O-N 3.03Å; R39-A43 WeakPolarHBondContact O-CB 3.5Å; R39-A43 PolarHBondContact O-N 3.49Å; R39-S331 PolarHBondContact NH1-O 3.44Å; R39-S332 PolarHBondContact NH1-O 3.08Å; R39-S332 PolarHBondContact NH2-O 3.46Å; R39-S332 VanDerWaalsContact NH2-O 3.1Å; R39-I333 PolarHBondContact NH2-O 3.49Å; R39-T335 VanDerWaalsContact NH1-CB 3.33Å; R39-S336 PolarHBondContact NH2-OG 2.86Å; R39-Y384 HydrophobicContact CG-CE1 3.93Å; R39-Y384 HydrophobicContact CG-CE2 4.14Å; R39-Y384 WeakPolarHBondContact CG-OH 3.43Å; R39-F389 HydrophobicContact CB-CE1 4.44Å; R39-F389 HydrophobicContact CB-CE2 3.86Å; R39-F389 HydrophobicContact CB-CZ 3.71Å; R39-F389 HydrophobicContact CG-CD1 4.45Å; R39-F389 HydrophobicContact CG-CD2 4.03Å; R39-F389 HydrophobicContact CG-CE1 4.09Å; R39-F389 HydrophobicContact CG-CE2 3.65Å; R39-F389 HydrophobicContact CG-CG 4.41Å; R39-F389 HydrophobicContact CG-CZ 3.68Å
40	L	89.3	Confident	85	Confident	47 Å²	47	30.5 Å²	30.5	25%	0.246	19%	0.187	C	C	.	.	H	α-helix	trans	-61.3	-40.3	177.1	-74.4	172	0	0	0	112.1	T36 V37 T38 Y42 A43 L44 F329 I333	T36-L40 HydrophobicContact CG2-CD1 4.06Å; T36-L40 HydrophobicContact CG2-CG 4.46Å; T36-L40 WeakPolarHBondContact O-CB 3.04Å; T36-L40 WeakPolarHBondContact O-CG 3.36Å; T36-L40 PolarHBondContact O-N 3.5Å; V37-L40 PolarHBondContact O-N 3.1Å; T38-L40 PolarHBondContact O-N 2.96Å; L40-Y42 PolarHBondContact O-N 3.17Å; L40-A43 PolarHBondContact O-N 2.96Å; L40-L44 WeakPolarHBondContact O-CB 3.41Å; L40-L44 VanDerWaalsContact O-CG 3.25Å; L40-L44 WeakPolarHBondContact O-CG 3.5Å; L40-L44 PolarHBondContact O-N 2.92Å; L40-F329 HydrophobicContact CD2-CD1 4.25Å; L40-I333 HydrophobicContact CD2-CG1 4.33Å
41	I	90.4	Very high	86.8	Confident	25 Å²	25	30.2 Å²	30.2	13%	0.128	19%	0.186	C	C	.	.	H	α-helix	trans	-63.5	-43.2	177	-64.2	164.8	0	0	0	110.8	C23 V37 T38 R39 A43 L44 F45 W126 F130	C23-I41 VanDerWaalsContact SG-CD1 3.54Å; V37-I41 HydrophobicContact CG1-CD1 3.95Å; V37-I41 HydrophobicContact CG1-CG1 4.5Å; V37-I41 WeakPolarHBondContact O-CG1 3.34Å; V37-I41 PolarHBondContact O-N 3.07Å; T38-I41 PolarHBondContact O-N 2.62Å; R39-I41 VanDerWaalsContact C-N 3.34Å; R39-I41 PolarHBondContact O-N 2.95Å; I41-A43 PolarHBondContact O-N 3.3Å; I41-L44 PolarHBondContact O-N 3.28Å; I41-F45 WeakPolarHBondContact O-CB 3.44Å; I41-F45 PolarHBondContact O-N 3.23Å; I41-W126 HydrophobicContact CB-CE3 4.39Å; I41-W126 HydrophobicContact CB-CH2 3.54Å; I41-W126 HydrophobicContact CB-CZ2 4.03Å; I41-W126 HydrophobicContact CB-CZ3 3.76Å; I41-W126 HydrophobicContact CD1-CD2 4.44Å; I41-W126 HydrophobicContact CD1-CH2 4.04Å; I41-W126 HydrophobicContact CD1-CZ2 3.57Å; I41-W126 HydrophobicContact CG1-CH2 4.39Å; I41-W126 HydrophobicContact CG1-CZ2 4.4Å; I41-W126 HydrophobicContact CG2-CD2 4.02Å; I41-W126 HydrophobicContact CG2-CE3 3.46Å; I41-W126 VanDerWaalsContact CG2-CE3 3.46Å; I41-W126 HydrophobicContact CG2-CH2 3.55Å; I41-W126 HydrophobicContact CG2-CZ2 4.09Å; I41-W126 HydrophobicContact CG2-CZ3 3.21Å; I41-F130 HydrophobicContact CG2-CZ 3.9Å
42	Y	93.1	Very high	88.5	Confident	0 Å²	0	28 Å²	28	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-64.3	-38.8	175.7	-74.7	-62.8	0	0	0	113	T38 R39 L40 F45 L46 Y101 L104 H122 W126 K129 F389 H390	T38-Y42 HydrophobicContact CG2-CD2 3.92Å; T38-Y42 HydrophobicContact CG2-CE2 3.52Å; T38-Y42 WeakPolarHBondContact O-CD2 3.46Å; T38-Y42 PolarHBondContact O-N 3.04Å; T38-Y42 VanDerWaalsContact O-N 3.16Å; R39-Y42 PolarHBondContact O-N 3.03Å; L40-Y42 PolarHBondContact O-N 3.17Å; Y42-F45 PolarHBondContact O-N 3.38Å; Y42-L46 PolarHBondContact O-N 3.03Å; Y42-Y101 HydrophobicContact CD1-CE1 4.17Å; Y42-Y101 PolarHBondContact O-OH 3.47Å; Y42-L104 HydrophobicContact CE1-CD1 3.77Å; Y42-H122 AromaticContact CE2-CE1 3.84Å; Y42-H122 PolarHBondContact OH-O 3.08Å; Y42-W126 HydrophobicContact CD1-CZ3 4.04Å; Y42-W126 AromaticContact CD2-CH2 3.99Å; Y42-W126 HydrophobicContact CD2-CH2 3.99Å; Y42-W126 HydrophobicContact CD2-CZ3 4.29Å; Y42-W126 HydrophobicContact CE1-CH2 4.36Å; Y42-W126 AromaticContact CE1-CZ3 3.83Å; Y42-W126 HydrophobicContact CE1-CZ3 3.83Å; Y42-W126 AromaticContact CE2-CH2 3.77Å; Y42-W126 HydrophobicContact CE2-CH2 3.77Å; Y42-W126 HydrophobicContact CE2-CZ3 4.1Å; Y42-W126 HydrophobicContact CG-CH2 4.37Å; Y42-W126 HydrophobicContact CG-CZ3 4.26Å; Y42-W126 AromaticContact CZ-CH2 3.96Å; Y42-W126 AromaticContact CZ-CZ3 3.85Å; Y42-K129 HydrophobicContact CE1-CD 4.29Å; Y42-K129 VanDerWaalsContact OH-CE 3.26Å; Y42-K129 WeakPolarHBondContact OH-CE 3.38Å; Y42-K129 PolarHBondContact OH-NZ 2.9Å; Y42-F389 AromaticContact CD2-CE1 3.82Å; Y42-F389 HydrophobicContact CD2-CE1 3.82Å; Y42-F389 HydrophobicContact CG-CE1 4.17Å; Y42-H390 AromaticContact CD1-CE1 3.91Å; Y42-H390 AromaticContact CD2-CE1 3.85Å; Y42-H390 AromaticContact CE1-CE1 3.65Å; Y42-H390 AromaticContact CE2-CE1 3.59Å; Y42-H390 AromaticContact CE2-NE2 3.89Å; Y42-H390 AromaticContact CZ-CE1 3.49Å; Y42-H390 VanDerWaalsContact CZ-CE1 3.49Å; Y42-H390 AromaticContact CZ-NE2 3.89Å
43	A	92.3	Very high	89.7	Confident	3 Å²	3	26.6 Å²	26.6	3%	0.025	15%	0.153	C	C	.	.	H	α-helix	trans	-64.4	-42.9	174.8	0	0	0	0	0	112.3	R39 L40 I41 F45 L46 L47 V328 S332	R39-A43 WeakPolarHBondContact O-CB 3.5Å; R39-A43 PolarHBondContact O-N 3.49Å; L40-A43 PolarHBondContact O-N 2.96Å; I41-A43 PolarHBondContact O-N 3.3Å; A43-F45 VanDerWaalsContact C-N 3.34Å; A43-L46 WeakPolarHBondContact O-CB 3.14Å; A43-L46 PolarHBondContact O-N 2.71Å; A43-L47 PolarHBondContact O-N 2.8Å; A43-V328 HydrophobicContact CB-CG1 3.6Å; A43-S332 WeakPolarHBondContact CB-OG 3.23Å
44	L	91.8	Very high	90.3	Very high	82 Å²	82	24.3 Å²	24.3	43%	0.429	14%	0.142	S	C	.	.	H	α-helix	trans	-65.1	-38	175	-71.2	172.5	0	0	0	111.7	L40 I41 L47 V48 F329	L40-L44 WeakPolarHBondContact O-CB 3.41Å; L40-L44 VanDerWaalsContact O-CG 3.25Å; L40-L44 WeakPolarHBondContact O-CG 3.5Å; L40-L44 PolarHBondContact O-N 2.92Å; I41-L44 PolarHBondContact O-N 3.28Å; L44-L47 HydrophobicContact CD2-CD2 4.45Å; L44-L47 WeakPolarHBondContact O-CB 3.34Å; L44-L47 PolarHBondContact O-N 3.45Å; L44-V48 WeakPolarHBondContact O-CG2 3.11Å; L44-V48 PolarHBondContact O-N 2.04Å; L44-F329 HydrophobicContact CD2-CE1 4.06Å; L44-F329 HydrophobicContact CD2-CZ 4.06Å
45	F	93.4	Very high	90.7	Very high	28 Å²	28	27.4 Å²	27.4	12%	0.123	16%	0.161	C	C	.	.	H	α-helix	trans	-63.5	-42.9	174.6	-176.2	-111.8	0	0	0	111.9	I41 Y42 A43 L47 V48 G49 L97 F100 Y101 F130 A133	I41-F45 WeakPolarHBondContact O-CB 3.44Å; I41-F45 PolarHBondContact O-N 3.23Å; Y42-F45 PolarHBondContact O-N 3.38Å; A43-F45 VanDerWaalsContact C-N 3.34Å; F45-L47 VanDerWaalsContact C-N 3.3Å; F45-L47 PolarHBondContact O-N 2.98Å; F45-V48 PolarHBondContact O-N 3.08Å; F45-G49 PolarHBondContact O-N 3.37Å; F45-G49 VanDerWaalsContact O-N 3.08Å; F45-L97 HydrophobicContact CE1-CD2 4.13Å; F45-F100 HydrophobicContact CD1-CE1 4.16Å; F45-F100 HydrophobicContact CE1-CD1 4.16Å; F45-F100 AromaticContact CE1-CE1 3.93Å; F45-F100 HydrophobicContact CE1-CE1 3.93Å; F45-Y101 WeakPolarHBondContact CD1-OH 3.44Å; F45-F130 HydrophobicContact CB-CE1 3.83Å; F45-F130 HydrophobicContact CB-CZ 4.38Å; F45-F130 HydrophobicContact CD1-CD1 4.29Å; F45-F130 HydrophobicContact CD1-CE1 4.18Å; F45-F130 AromaticContact CD2-CD1 3.48Å; F45-F130 HydrophobicContact CD2-CD1 3.48Å; F45-F130 VanDerWaalsContact CD2-CD1 3.48Å; F45-F130 AromaticContact CD2-CE1 3.43Å; F45-F130 HydrophobicContact CD2-CE1 3.43Å; F45-F130 VanDerWaalsContact CD2-CE1 3.43Å; F45-F130 HydrophobicContact CD2-CG 4.28Å; F45-F130 HydrophobicContact CD2-CZ 4.17Å; F45-F130 HydrophobicContact CE1-CD1 4.36Å; F45-F130 HydrophobicContact CE2-CB 4.45Å; F45-F130 AromaticContact CE2-CD1 3.56Å; F45-F130 HydrophobicContact CE2-CD1 3.56Å; F45-F130 HydrophobicContact CE2-CE1 4.03Å; F45-F130 HydrophobicContact CE2-CG 4.16Å; F45-F130 AromaticContact CG-CD1 3.88Å; F45-F130 HydrophobicContact CG-CD1 3.88Å; F45-F130 AromaticContact CG-CE1 3.53Å; F45-F130 HydrophobicContact CG-CE1 3.53Å; F45-F130 HydrophobicContact CG-CZ 4.41Å; F45-F130 HydrophobicContact CZ-CD1 4.03Å; F45-A133 HydrophobicContact CE1-CB 3.64Å; F45-A133 HydrophobicContact CZ-CB 3.46Å; F45-A133 VanDerWaalsContact CZ-CB 3.46Å
46	L	94.9	Very high	90.9	Very high	2 Å²	2	28.5 Å²	28.5	1%	0.01	17%	0.166	C	C	.	.	H	α-helix	trans	-58.6	-45.5	172.5	-178.7	60.2	0	0	0	110.4	Y42 A43 V48 G49 V50 Y101 F324 L393 A396	Y42-L46 PolarHBondContact O-N 3.03Å; A43-L46 WeakPolarHBondContact O-CB 3.14Å; A43-L46 PolarHBondContact O-N 2.71Å; L46-V48 PolarHBondContact O-N 3.46Å; L46-G49 CarbonylContact O-C 3.6Å; L46-G49 WeakPolarHBondContact O-CA 3.48Å; L46-G49 PolarHBondContact O-N 3.05Å; L46-V50 VanDerWaalsContact O-CG2 3.3Å; L46-V50 WeakPolarHBondContact O-CG2 3.48Å; L46-V50 PolarHBondContact O-N 2.84Å; L46-Y101 HydrophobicContact CB-CE2 4.31Å; L46-Y101 WeakPolarHBondContact CB-OH 3.41Å; L46-Y101 HydrophobicContact CD1-CE2 3.9Å; L46-Y101 PolarHBondContact N-OH 3.44Å; L46-F324 HydrophobicContact CD2-CZ 3.74Å; L46-F324 HydrophobicContact CG-CZ 4.23Å; L46-L393 HydrophobicContact CD2-CD2 3.87Å; L46-A396 HydrophobicContact CD2-CB 3.77Å
47	L	93.7	Very high	90.9	Very high	40 Å²	40	28 Å²	28	21%	0.209	16%	0.163	C	C	.	.	H	α-helix	trans	-59.6	-42.8	178	178.9	53.8	0	0	0	112.7	A43 L44 F45 G49 V50 C51 L325 F329	A43-L47 PolarHBondContact O-N 2.8Å; L44-L47 HydrophobicContact CD2-CD2 4.45Å; L44-L47 WeakPolarHBondContact O-CB 3.34Å; L44-L47 PolarHBondContact O-N 3.45Å; F45-L47 VanDerWaalsContact C-N 3.3Å; F45-L47 PolarHBondContact O-N 2.98Å; L47-G49 VanDerWaalsContact C-N 3.26Å; L47-G49 PolarHBondContact O-N 3.24Å; L47-V50 CarbonylContact O-C 3.53Å; L47-V50 WeakPolarHBondContact O-CB 3.46Å; L47-V50 PolarHBondContact O-N 2.97Å; L47-V50 VanDerWaalsContact O-N 3.08Å; L47-C51 PolarHBondContact O-N 3.17Å; L47-C51 PolarHBondContact O-SG 3.05Å; L47-C51 VanDerWaalsContact O-SG 3.35Å; L47-L325 HydrophobicContact CD1-CD1 4.49Å; L47-L325 HydrophobicContact CD1-CD2 3.27Å; L47-L325 HydrophobicContact CD2-CD2 4.44Å; L47-L325 HydrophobicContact CG-CD2 4.35Å; L47-F329 HydrophobicContact CD2-CE2 4.27Å; L47-F329 HydrophobicContact CD2-CZ 4Å
48	V	94.1	Very high	90.8	Very high	87 Å²	87	31.3 Å²	31.3	53%	0.527	18%	0.179	S	C	.	.	H	α-helix	trans	-58.1	-43.7	172.9	170.9	0	0	0	0	110.3	L44 F45 L46 V50 C51 V52	L44-V48 WeakPolarHBondContact O-CG2 3.11Å; L44-V48 PolarHBondContact O-N 2.04Å; F45-V48 PolarHBondContact O-N 3.08Å; L46-V48 PolarHBondContact O-N 3.46Å; V48-V50 VanDerWaalsContact C-N 3.34Å; V48-V50 PolarHBondContact O-N 2.94Å; V48-C51 PolarHBondContact O-N 3.48Å; V48-V52 WeakPolarHBondContact O-CG2 3.31Å; V48-V52 PolarHBondContact O-N 3.16Å
49	G	94.8	Very high	90	Very high	9 Å²	9	34.6 Å²	34.6	9%	0.093	20%	0.2	C	C	.	.	H	α-helix	trans	-56.8	-44.5	172.1	0	0	0	0	0	113	F45 L46 L47 V52 A53 L93	F45-G49 PolarHBondContact O-N 3.37Å; F45-G49 VanDerWaalsContact O-N 3.08Å; L46-G49 CarbonylContact O-C 3.6Å; L46-G49 WeakPolarHBondContact O-CA 3.48Å; L46-G49 PolarHBondContact O-N 3.05Å; L47-G49 VanDerWaalsContact C-N 3.26Å; L47-G49 PolarHBondContact O-N 3.24Å; G49-V52 PolarHBondContact O-N 2.9Å; G49-A53 PolarHBondContact O-N 2.82Å; G49-L93 WeakPolarHBondContact O-CD2 3.39Å
50	V	94.1	Very high	89.2	Confident	4 Å²	4	37.2 Å²	37.2	2%	0.024	23%	0.228	C	C	.	.	H	α-helix	trans	-63.4	-42.9	175.8	-174.8	0	0	0	0	111.7	L46 L47 V48 V52 A53 C54 L321 F324 I400	L46-V50 VanDerWaalsContact O-CG2 3.3Å; L46-V50 WeakPolarHBondContact O-CG2 3.48Å; L46-V50 PolarHBondContact O-N 2.84Å; L47-V50 CarbonylContact O-C 3.53Å; L47-V50 WeakPolarHBondContact O-CB 3.46Å; L47-V50 PolarHBondContact O-N 2.97Å; L47-V50 VanDerWaalsContact O-N 3.08Å; V48-V50 VanDerWaalsContact C-N 3.34Å; V48-V50 PolarHBondContact O-N 2.94Å; V50-V52 VanDerWaalsContact C-N 3.33Å; V50-V52 PolarHBondContact O-N 3.38Å; V50-A53 WeakPolarHBondContact O-CB 3.49Å; V50-A53 PolarHBondContact O-N 3.3Å; V50-C54 PolarHBondContact O-N 2.86Å; V50-C54 PolarHBondContact O-SG 3.41Å; V50-L321 HydrophobicContact CG1-CD1 3.58Å; V50-F324 HydrophobicContact CG2-CE1 4.08Å; V50-F324 HydrophobicContact CG2-CZ 4.44Å; V50-I400 HydrophobicContact CB-CG2 4.43Å; V50-I400 HydrophobicContact CG1-CD1 4.45Å; V50-I400 HydrophobicContact CG1-CG2 3.97Å; V50-I400 HydrophobicContact CG2-CB 4.47Å; V50-I400 HydrophobicContact CG2-CG1 4.02Å; V50-I400 HydrophobicContact CG2-CG2 3.91Å
51	C	93.1	Very high	88.7	Confident	68 Å²	68	37.6 Å²	37.6	46%	0.459	23%	0.229	S	C	.	.	H	α-helix	trans	-60.1	-43.9	176.3	-69	0	0	0	0	111.5	L47 V48 A53 C54 V55	L47-C51 PolarHBondContact O-N 3.17Å; L47-C51 PolarHBondContact O-SG 3.05Å; L47-C51 VanDerWaalsContact O-SG 3.35Å; V48-C51 PolarHBondContact O-N 3.48Å; C51-A53 VanDerWaalsContact C-N 3.33Å; C51-A53 PolarHBondContact O-N 3.23Å; C51-C54 PolarHBondContact O-N 3.48Å; C51-V55 WeakPolarHBondContact O-CB 2.84Å; C51-V55 VanDerWaalsContact O-CG2 3.23Å; C51-V55 WeakPolarHBondContact O-CG2 3.31Å; C51-V55 PolarHBondContact O-N 2.94Å
52	V	93.1	Very high	87.8	Confident	59 Å²	59	39 Å²	39	36%	0.358	24%	0.235	S	C	.	.	H	α-helix	trans	-62	-42	175.4	174.2	0	0	0	0	110.9	V48 G49 V50 V55 M56 L93	V48-V52 WeakPolarHBondContact O-CG2 3.31Å; V48-V52 PolarHBondContact O-N 3.16Å; G49-V52 PolarHBondContact O-N 2.9Å; V50-V52 VanDerWaalsContact C-N 3.33Å; V50-V52 PolarHBondContact O-N 3.38Å; V52-V55 PolarHBondContact O-N 3.16Å; V52-M56 HydrophobicContact CG1-CE 3.74Å; V52-M56 HydrophobicContact CG1-SD 4.36Å; V52-M56 WeakPolarHBondContact O-CG 3.28Å; V52-M56 PolarHBondContact O-N 2.9Å; V52-L93 HydrophobicContact CB-CD2 4.37Å; V52-L93 HydrophobicContact CG1-CD1 3.82Å; V52-L93 HydrophobicContact CG1-CD2 4.21Å
53	A	92.4	Very high	86.8	Confident	0 Å²	0	45.5 Å²	45.5	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-61.3	-44.9	175.7	0	0	0	0	0	112.3	G49 V50 C51 V55 M56 L57 V90 L93 L404	G49-A53 PolarHBondContact O-N 2.82Å; V50-A53 WeakPolarHBondContact O-CB 3.49Å; V50-A53 PolarHBondContact O-N 3.3Å; C51-A53 VanDerWaalsContact C-N 3.33Å; C51-A53 PolarHBondContact O-N 3.23Å; A53-V55 VanDerWaalsContact C-N 3.31Å; A53-V55 PolarHBondContact O-N 2.88Å; A53-M56 WeakPolarHBondContact O-CB 3.42Å; A53-M56 PolarHBondContact O-N 3.44Å; A53-L57 PolarHBondContact O-N 3.31Å; A53-V90 HydrophobicContact CB-CG2 4.31Å; A53-L93 HydrophobicContact CB-CD2 3.56Å; A53-L404 HydrophobicContact CB-CD1 3.46Å; A53-L404 VanDerWaalsContact CB-CD1 3.46Å
54	C	89.7	Confident	86.1	Confident	17 Å²	17	50.5 Å²	50.5	12%	0.115	29%	0.288	C	S	.	.	H	α-helix	trans	-60.8	-42.1	175.6	-71.3	0	0	0	0	111.6	V50 C51 L57 I58 W313	V50-C54 PolarHBondContact O-N 2.86Å; V50-C54 PolarHBondContact O-SG 3.41Å; C51-C54 PolarHBondContact O-N 3.48Å; C54-L57 PolarHBondContact O-N 3.21Å; C54-L57 VanDerWaalsContact O-N 3.16Å; C54-I58 PolarHBondContact O-N 3.35Å; C54-W313 HydrophobicContact CB-CZ2 3.98Å
55	V	88.6	Confident	85.3	Confident	67 Å²	67	47 Å²	47	41%	0.406	27%	0.27	S	S	.	.	H	α-helix	trans	-61.6	-44.4	177.5	165.5	0	0	0	0	110.3	C51 V52 A53 L57 I58 M61	C51-V55 WeakPolarHBondContact O-CB 2.84Å; C51-V55 VanDerWaalsContact O-CG2 3.23Å; C51-V55 WeakPolarHBondContact O-CG2 3.31Å; C51-V55 PolarHBondContact O-N 2.94Å; V52-V55 PolarHBondContact O-N 3.16Å; A53-V55 VanDerWaalsContact C-N 3.31Å; A53-V55 PolarHBondContact O-N 2.88Å; V55-L57 PolarHBondContact O-N 3.39Å; V55-L57 VanDerWaalsContact O-N 3.08Å; V55-I58 HydrophobicContact CB-CD1 4.5Å; V55-I58 HydrophobicContact CG2-CD1 4.26Å; V55-I58 WeakPolarHBondContact O-CB 3.36Å; V55-I58 PolarHBondContact O-N 3.43Å; V55-M61 HydrophobicContact CB-SD 4.21Å; V55-M61 HydrophobicContact CG1-CE 4.07Å; V55-M61 HydrophobicContact CG1-SD 3.14Å; V55-M61 WeakPolarHBondContact CG1-SD 2.9Å
56	M	86.1	Confident	84.3	Confident	23 Å²	23	47.8 Å²	47.8	11%	0.113	28%	0.276	C	S	.	.	H	α-helix	trans	-59.3	-20	175	-70.3	174.2	173.7	0	0	114.8	V52 A53 M61 L65 G86 A89 L93 F141	V52-M56 HydrophobicContact CG1-CE 3.74Å; V52-M56 HydrophobicContact CG1-SD 4.36Å; V52-M56 WeakPolarHBondContact O-CG 3.28Å; V52-M56 PolarHBondContact O-N 2.9Å; A53-M56 WeakPolarHBondContact O-CB 3.42Å; A53-M56 PolarHBondContact O-N 3.44Å; M56-M61 HydrophobicContact CG-CE 4.46Å; M56-L65 HydrophobicContact CB-CD1 4.26Å; M56-G86 WeakPolarHBondContact O-CA 3.26Å; M56-A89 HydrophobicContact CB-CB 4.41Å; M56-A89 HydrophobicContact SD-CB 3.94Å; M56-L93 HydrophobicContact CE-CD1 3.96Å; M56-L93 HydrophobicContact SD-CB 4.32Å; M56-L93 HydrophobicContact SD-CD1 4.38Å; M56-L93 HydrophobicContact SD-CD2 4.42Å; M56-F141 HydrophobicContact CE-CE2 4.47Å; M56-F141 HydrophobicContact CE-CZ 3.73Å; M56-F141 HydrophobicContact SD-CZ 4.24Å
57	L	82.7	Confident	83.3	Confident	16 Å²	16	54.1 Å²	54.1	8%	0.084	30%	0.303	C	S	.	.	T	Hydrogen-bonded Turn	trans	-93.2	-5.7	176.3	-68.3	172.8	0	0	0	113.8	A53 C54 V55 Y87 V90 L404	A53-L57 PolarHBondContact O-N 3.31Å; C54-L57 PolarHBondContact O-N 3.21Å; C54-L57 VanDerWaalsContact O-N 3.16Å; V55-L57 PolarHBondContact O-N 3.39Å; V55-L57 VanDerWaalsContact O-N 3.08Å; L57-Y87 HydrophobicContact CD2-CD2 4.02Å; L57-Y87 HydrophobicContact CD2-CE2 4.27Å; L57-Y87 HydrophobicContact CD2-CG 4.47Å; L57-V90 HydrophobicContact CD1-CG2 3.98Å; L57-V90 HydrophobicContact CD2-CG2 3.9Å; L57-V90 HydrophobicContact CG-CG2 3.71Å; L57-L404 HydrophobicContact CD1-CB 3.9Å; L57-L404 HydrophobicContact CD1-CD2 4.49Å
58	I	80.9	Confident	82.3	Confident	80 Å²	80	54.9 Å²	54.9	41%	0.41	31%	0.307	S	S	.	.	S	Bend	trans	-69.2	131.5	-179.7	-65	175.5	0	0	0	109.6	C54 V55 G60 M61	C54-I58 PolarHBondContact O-N 3.35Å; V55-I58 HydrophobicContact CB-CD1 4.5Å; V55-I58 HydrophobicContact CG2-CD1 4.26Å; V55-I58 WeakPolarHBondContact O-CB 3.36Å; V55-I58 PolarHBondContact O-N 3.43Å; I58-G60 PolarHBondContact O-N 3.45Å; I58-G60 VanDerWaalsContact O-N 3.17Å; I58-M61 PolarHBondContact O-N 3.06Å; I58-M61 VanDerWaalsContact O-N 3.08Å
59	P	71.4	Confident	80.9	Confident	69 Å²	69	54.9 Å²	54.9	45%	0.448	31%	0.308	S	S	.	.	T	Hydrogen-bonded Turn	trans	-57.4	122.8	174.5	23.9	-33.5	0	0	0	110	W312	P59-W312 HydrophobicContact CG-CD2 4.39Å
60	G	74.4	Confident	79.5	Confident	56 Å²	56	56 Å²	56	58%	0.577	32%	0.32	S	S	*	.	T	Hydrogen-bonded Turn	trans	115.3	-24.4	-174.4	0	0	0	0	0	114.3	I58 E62	I58-G60 PolarHBondContact O-N 3.45Å; I58-G60 VanDerWaalsContact O-N 3.17Å; G60-E62 VanDerWaalsContact C-N 3.27Å; G60-E62 PolarHBondContact O-N 3.33Å
61	M	78.5	Confident	78.2	Confident	54 Å²	54	55.9 Å²	55.9	27%	0.266	32%	0.319	S	S	.	.	S	Bend	trans	-75.3	-18.6	171.6	-77.1	-154.1	56.2	0	0	113.7	V55 M56 I58 E63 Q64 L65	V55-M61 HydrophobicContact CB-SD 4.21Å; V55-M61 HydrophobicContact CG1-CE 4.07Å; V55-M61 HydrophobicContact CG1-SD 3.14Å; V55-M61 WeakPolarHBondContact CG1-SD 2.9Å; M56-M61 HydrophobicContact CG-CE 4.46Å; I58-M61 PolarHBondContact O-N 3.06Å; I58-M61 VanDerWaalsContact O-N 3.08Å; M61-E63 PolarHBondContact O-N 3.25Å; M61-Q64 PolarHBondContact O-N 2.97Å; M61-L65 HydrophobicContact CB-CD1 4.45Å; M61-L65 WeakPolarHBondContact O-CG 3.49Å; M61-L65 PolarHBondContact O-N 3.49Å
62	E	71.6	Confident	76.9	Confident	55 Å²	55	54.4 Å²	54.4	26%	0.257	31%	0.309	S	S	.	.	H	α-helix	trans	-52.2	-41.7	175.9	-61.1	177.3	-170.5	0	0	111.8	G60 Q64 L65 N66 N82	G60-E62 VanDerWaalsContact C-N 3.27Å; G60-E62 PolarHBondContact O-N 3.33Å; E62-Q64 VanDerWaalsContact C-N 3.32Å; E62-Q64 PolarHBondContact O-N 2.96Å; E62-L65 PolarHBondContact O-N 3.18Å; E62-N66 WeakPolarHBondContact O-CB 3.38Å; E62-N66 PolarHBondContact O-N 3.28Å; E62-N66 PolarHBondContact O-ND2 3.45Å; E62-N82 WeakPolarHBondContact CG-O 3.4Å
63	E	71.3	Confident	75.2	Confident	136 Å²	136	57.8 Å²	57.8	64%	0.636	32%	0.321	S	S	*	.	H	α-helix	trans	-65.1	-35.1	-179.8	-168.8	-178.1	175.8	0	0	112.5	M61	M61-E63 PolarHBondContact O-N 3.25Å
64	Q	76.8	Confident	73.4	Confident	108 Å²	108	65.5 Å²	65.5	51%	0.505	36%	0.362	S	S	.	.	H	α-helix	trans	-77.1	-39.2	176.9	-59.4	-59.9	-21.9	0	0	111.4	M61 E62 N66 K67	M61-Q64 PolarHBondContact O-N 2.97Å; E62-Q64 VanDerWaalsContact C-N 3.32Å; E62-Q64 PolarHBondContact O-N 2.96Å; Q64-N66 VanDerWaalsContact C-N 3.33Å; Q64-K67 WeakPolarHBondContact O-CB 3.38Å; Q64-K67 PolarHBondContact O-N 2.96Å
65	L	76	Confident	71.7	Confident	9 Å²	9	67.2 Å²	67.2	5%	0.047	37%	0.369	C	S	.	.	H	α-helix	trans	-69.3	-33	178.2	-68.3	170.4	0	0	0	111.9	M56 M61 E62 K67 I68 V85 A89	M56-L65 HydrophobicContact CB-CD1 4.26Å; M61-L65 HydrophobicContact CB-CD1 4.45Å; M61-L65 WeakPolarHBondContact O-CG 3.49Å; M61-L65 PolarHBondContact O-N 3.49Å; E62-L65 PolarHBondContact O-N 3.18Å; L65-K67 PolarHBondContact O-N 3.2Å; L65-I68 HydrophobicContact CD2-CD1 3.97Å; L65-I68 WeakPolarHBondContact O-CB 3.31Å; L65-I68 WeakPolarHBondContact O-CG1 3.32Å; L65-I68 PolarHBondContact O-N 3.4Å; L65-V85 HydrophobicContact CB-CG1 3.28Å; L65-V85 HydrophobicContact CD1-CG1 4.17Å; L65-V85 HydrophobicContact CG-CG1 4.35Å; L65-A89 HydrophobicContact CD1-CB 4.03Å; L65-A89 HydrophobicContact CD2-CB 4.08Å
66	N	71.1	Confident	69.7	Low	45 Å²	45	74.3 Å²	74.3	24%	0.241	39%	0.394	C	S	.	.	T	Hydrogen-bonded Turn	trans	-61.7	-21.6	174.1	-82.7	-19.4	0	0	0	113.6	E62 Q64 I68 C72 N82 V85	E62-N66 WeakPolarHBondContact O-CB 3.38Å; E62-N66 PolarHBondContact O-N 3.28Å; E62-N66 PolarHBondContact O-ND2 3.45Å; Q64-N66 VanDerWaalsContact C-N 3.33Å; N66-I68 PolarHBondContact O-N 3.34Å; N66-C72 PolarHBondContact OD1-SG 3.44Å; N66-C72 VanDerWaalsContact OD1-SG 3.38Å; N66-N82 VanDerWaalsContact ND2-CG 3.33Å; N66-N82 PolarHBondContact ND2-OD1 3Å; N66-V85 WeakPolarHBondContact OD1-CG2 3.4Å
67	K	75	Confident	68.1	Low	135 Å²	135	75.2 Å²	75.2	59%	0.587	41%	0.409	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.3	-13.2	175.5	-64.3	172.9	-173.5	169.7	0	112.7	Q64 L65	Q64-K67 WeakPolarHBondContact O-CB 3.38Å; Q64-K67 PolarHBondContact O-N 2.96Å; L65-K67 PolarHBondContact O-N 3.2Å
68	I	72.7	Confident	66.5	Low	56 Å²	56	81.4 Å²	81.4	29%	0.287	45%	0.447	S	S	.	.	S	Bend	trans	-77.2	120	178.9	-56.3	174.5	0	0	0	108.1	L65 N66 G70 F71 F141	L65-I68 HydrophobicContact CD2-CD1 3.97Å; L65-I68 WeakPolarHBondContact O-CB 3.31Å; L65-I68 WeakPolarHBondContact O-CG1 3.32Å; L65-I68 PolarHBondContact O-N 3.4Å; N66-I68 PolarHBondContact O-N 3.34Å; I68-G70 PolarHBondContact O-N 3.2Å; I68-F71 HydrophobicContact CB-CD2 3.89Å; I68-F71 HydrophobicContact CB-CE2 4.18Å; I68-F71 HydrophobicContact CG2-CD2 3.78Å; I68-F71 HydrophobicContact CG2-CE2 3.77Å; I68-F141 HydrophobicContact CD1-CD1 4.26Å; I68-F141 HydrophobicContact CD1-CE1 4.41Å
69	P	64.9	Low	65.3	Low	87 Å²	87	80 Å²	80	57%	0.565	44%	0.443	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.8	140.5	-179.8	25.1	-33.3	0	0	0	110.5
70	G	65.1	Low	64.7	Low	33 Å²	33	79.6 Å²	79.6	34%	0.34	44%	0.44	S	S	.	.	T	Hydrogen-bonded Turn	trans	93.4	-8.3	179.6	0	0	0	0	0	117.3	I68	I68-G70 PolarHBondContact O-N 3.2Å
71	F	66.7	Low	64.3	Low	1 Å²	1	77.7 Å²	77.7	0%	0.004	42%	0.417	C	S	.	.	S	Bend	trans	-83.1	-34.7	177.6	-87.2	-104.5	0	0	0	114.3	I68 C81 V85 K88 A89 F141 E145	I68-F71 HydrophobicContact CB-CD2 3.89Å; I68-F71 HydrophobicContact CB-CE2 4.18Å; I68-F71 HydrophobicContact CG2-CD2 3.78Å; I68-F71 HydrophobicContact CG2-CE2 3.77Å; F71-C81 PolarHBondContact O-SG 2.87Å; F71-V85 HydrophobicContact CD1-CG1 3.95Å; F71-K88 HydrophobicContact CD1-CB 3.93Å; F71-K88 HydrophobicContact CE1-CB 3.8Å; F71-K88 PolarHBondContact O-NZ 3.02Å; F71-A89 HydrophobicContact CE1-CB 3.99Å; F71-A89 HydrophobicContact CZ-CB 4.35Å; F71-F141 AromaticContact CE2-CD1 3.76Å; F71-F141 HydrophobicContact CE2-CD1 3.76Å; F71-F141 HydrophobicContact CE2-CE1 4.32Å; F71-F141 AromaticContact CZ-CD1 3.61Å; F71-F141 HydrophobicContact CZ-CD1 3.61Å; F71-F141 AromaticContact CZ-CE1 3.75Å; F71-F141 HydrophobicContact CZ-CE1 3.75Å; F71-E145 WeakPolarHBondContact CA-OE1 3.35Å
72	C	65.3	Low	63.6	Low	36 Å²	36	78.8 Å²	78.8	24%	0.243	42%	0.424	C	S	.	.	S	Bend	trans	-139.6	12.2	-177.5	-62.9	0	0	0	0	113.8	N66 N74 C81 V85	N66-C72 PolarHBondContact OD1-SG 3.44Å; N66-C72 VanDerWaalsContact OD1-SG 3.38Å; C72-N74 PolarHBondContact O-N 3.25Å; C72-C81 VanDerWaalsContact CA-SG 3.52Å; C72-C81 HydrophobicContact CB-CB 3.81Å; C72-C81 WeakPolarHBondContact CB-SG 3.2Å; C72-C81 WeakPolarHBondContact SG-CB 3.41Å; C72-C81 CovalentContact SG-SG 2.04Å; C72-C81 PolarHBondContact SG-SG 3.09Å; C72-V85 WeakPolarHBondContact SG-CG2 3.48Å
73	E	57.2	Low	63.1	Low	131 Å²	131	77.7 Å²	77.7	61%	0.612	42%	0.42	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.3	118.6	178.8	-73.2	-179.5	161.1	0	0	110.3
74	N	55	Low	63.1	Low	162 Å²	162	72.3 Å²	72.3	87%	0.866	40%	0.395	S	S	*	.	T	Hydrogen-bonded Turn	trans	81.6	14.5	177.4	-49.9	-59.5	0	0	0	117.9	C72 K76	C72-N74 PolarHBondContact O-N 3.25Å; N74-K76 PolarHBondContact O-N 2.83Å; N74-K76 VanDerWaalsContact O-N 3.07Å
75	E	54.5	Low	63.3	Low	53 Å²	53	67.1 Å²	67.1	25%	0.248	37%	0.371	C	S	.	.			trans	-85.9	75.7	-173.5	-70.5	-127.6	100	0	0	114.5	G77 C81 K88 R414	E75-G77 PolarHBondContact O-N 3.21Å; E75-C81 PolarHBondContact OE2-SG 3.23Å; E75-C81 VanDerWaalsContact OE2-SG 3.38Å; E75-K88 IonicContact OE2-NZ 3.03Å; E75-K88 PolarHBondContact OE2-NZ 3.18Å; E75-R414 VanDerWaalsContact CB-NH2 3.28Å; E75-R414 VanDerWaalsContact CD-NH2 3.26Å; E75-R414 PolarHBondContact O-NH1 3.14Å; E75-R414 IonicContact OE1-CZ 3.64Å; E75-R414 IonicContact OE1-NE 2.74Å; E75-R414 IonicContact OE1-NH2 3.3Å; E75-R414 PolarHBondContact OE1-NH2 3.35Å; E75-R414 IonicContact OE2-NH2 3.02Å
76	K	47	Very low	63.5	Low	216 Å²	216	67 Å²	67	94%	0.939	37%	0.371	S	S	*	.			trans	-76.8	97.7	166.3	-67.8	-175.4	-177.5	179.7	0	110.9	N74	N74-K76 PolarHBondContact O-N 2.83Å; N74-K76 VanDerWaalsContact O-N 3.07Å
77	G	51.4	Low	64	Low	42 Å²	42	65.7 Å²	65.7	43%	0.433	36%	0.363	S	S	.	.	S	Bend	trans	-157.3	169	174.3	0	0	0	0	0	112.4	E75 V79	E75-G77 PolarHBondContact O-N 3.21Å; G77-V79 VanDerWaalsContact C-N 3.28Å; G77-V79 PolarHBondContact O-N 3.31Å
78	V	49.3	Very low	64.4	Low	145 Å²	145	59.7 Å²	59.7	88%	0.879	34%	0.337	S	S	*	.	S	Bend	trans	-65.8	-27.6	-166.2	-176.7	0	0	0	0	113.2
79	V	56	Low	65.2	Low	52 Å²	52	57 Å²	57	32%	0.315	32%	0.324	S	S	.	.	S	Bend	trans	-100.3	127.9	178	-175.4	0	0	0	0	109.6	G77 C81 R414	G77-V79 VanDerWaalsContact C-N 3.28Å; G77-V79 PolarHBondContact O-N 3.31Å; V79-C81 PolarHBondContact O-N 3.32Å; V79-R414 HydrophobicContact CB-CB 4.19Å; V79-R414 HydrophobicContact CG2-CB 4.15Å
80	P	59.1	Low	66.4	Low	59 Å²	59	52.9 Å²	52.9	38%	0.383	30%	0.297	S	S	.	.			trans	-63	122.1	177	24.2	-31.6	0	0	0	109.9	N82 I83	P80-N82 PolarHBondContact O-N 3.03Å; P80-I83 HydrophobicContact CG-CD1 3.73Å; P80-I83 HydrophobicContact CG-CG1 4.11Å; P80-I83 PolarHBondContact O-N 3.02Å; P80-I83 VanDerWaalsContact O-N 3.14Å
81	C	67	Low	67.6	Low	16 Å²	16	52.1 Å²	52.1	11%	0.108	28%	0.284	C	S	.	.	T	Hydrogen-bonded Turn	trans	-49.9	-32.4	-178.7	-178.2	0	0	0	0	112.7	F71 C72 E75 V79 I83 L84 V85	F71-C81 PolarHBondContact O-SG 2.87Å; C72-C81 VanDerWaalsContact CA-SG 3.52Å; C72-C81 HydrophobicContact CB-CB 3.81Å; C72-C81 WeakPolarHBondContact CB-SG 3.2Å; C72-C81 WeakPolarHBondContact SG-CB 3.41Å; C72-C81 CovalentContact SG-SG 2.04Å; C72-C81 PolarHBondContact SG-SG 3.09Å; E75-C81 PolarHBondContact OE2-SG 3.23Å; E75-C81 VanDerWaalsContact OE2-SG 3.38Å; V79-C81 PolarHBondContact O-N 3.32Å; C81-I83 PolarHBondContact O-N 3.46Å; C81-I83 VanDerWaalsContact O-N 3.1Å; C81-L84 PolarHBondContact O-N 3.11Å; C81-V85 WeakPolarHBondContact O-CG2 3.42Å; C81-V85 PolarHBondContact O-N 3.25Å
82	N	62.5	Low	68.8	Low	77 Å²	77	52.1 Å²	52.1	41%	0.412	28%	0.284	S	S	.	.	H	α-helix	trans	-42.9	-45.9	176.8	-60.9	-1.3	0	0	0	113.2	E62 N66 P80 L84 V85	E62-N82 WeakPolarHBondContact CG-O 3.4Å; N66-N82 VanDerWaalsContact ND2-CG 3.33Å; N66-N82 PolarHBondContact ND2-OD1 3Å; P80-N82 PolarHBondContact O-N 3.03Å; N82-L84 VanDerWaalsContact C-N 3.25Å; N82-L84 PolarHBondContact O-N 3.43Å; N82-V85 PolarHBondContact O-N 3.1Å
83	I	62.1	Low	70.2	Confident	32 Å²	32	50.8 Å²	50.8	16%	0.164	27%	0.274	C	S	.	.	H	α-helix	trans	-68.2	-27.8	-175.3	-60.5	179.3	0	0	0	111.9	P80 C81 V310	P80-I83 HydrophobicContact CG-CD1 3.73Å; P80-I83 HydrophobicContact CG-CG1 4.11Å; P80-I83 PolarHBondContact O-N 3.02Å; P80-I83 VanDerWaalsContact O-N 3.14Å; C81-I83 PolarHBondContact O-N 3.46Å; C81-I83 VanDerWaalsContact O-N 3.1Å; I83-V310 HydrophobicContact CG2-CG2 3.14Å
84	L	71.4	Confident	72	Confident	23 Å²	23	44.6 Å²	44.6	12%	0.12	25%	0.245	C	C	.	.	H	α-helix	trans	-95.7	-16.8	-174.3	-171.7	62.8	0	0	0	113	C81 N82 G86 Y87 K88 Y410 M416	C81-L84 PolarHBondContact O-N 3.11Å; N82-L84 VanDerWaalsContact C-N 3.25Å; N82-L84 PolarHBondContact O-N 3.43Å; L84-G86 VanDerWaalsContact C-N 3.27Å; L84-G86 PolarHBondContact O-N 2.87Å; L84-Y87 HydrophobicContact CD1-CG 4.44Å; L84-Y87 WeakPolarHBondContact O-CB 3.38Å; L84-Y87 PolarHBondContact O-N 2.84Å; L84-K88 HydrophobicContact CD2-CG 4.49Å; L84-K88 HydrophobicContact CG-CG 4.07Å; L84-K88 WeakPolarHBondContact O-CG 3.2Å; L84-K88 PolarHBondContact O-N 2.96Å; L84-Y410 HydrophobicContact CD1-CD2 4.47Å; L84-Y410 HydrophobicContact CD2-CD2 3.45Å; L84-Y410 VanDerWaalsContact CD2-CD2 3.45Å; L84-Y410 HydrophobicContact CD2-CE2 3.1Å; L84-Y410 HydrophobicContact CG-CE2 4.5Å; L84-M416 HydrophobicContact CD1-CE 3.21Å; L84-M416 HydrophobicContact CD1-SD 4.41Å
85	V	79.1	Confident	74	Confident	0 Å²	0	38.9 Å²	38.9	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-57.9	-38.9	-173.5	170.4	0	0	0	0	112.3	L65 N66 F71 C72 C81 N82 Y87 K88 A89	L65-V85 HydrophobicContact CB-CG1 3.28Å; L65-V85 HydrophobicContact CD1-CG1 4.17Å; L65-V85 HydrophobicContact CG-CG1 4.35Å; N66-V85 WeakPolarHBondContact OD1-CG2 3.4Å; F71-V85 HydrophobicContact CD1-CG1 3.95Å; C72-V85 WeakPolarHBondContact SG-CG2 3.48Å; C81-V85 WeakPolarHBondContact O-CG2 3.42Å; C81-V85 PolarHBondContact O-N 3.25Å; N82-V85 PolarHBondContact O-N 3.1Å; V85-Y87 PolarHBondContact O-N 3.47Å; V85-K88 PolarHBondContact O-N 3.41Å; V85-A89 WeakPolarHBondContact O-CB 3.42Å; V85-A89 PolarHBondContact O-N 3.36Å
86	G	81.6	Confident	76	Confident	5 Å²	5	36.4 Å²	36.4	5%	0.052	20%	0.201	C	C	.	.	H	α-helix	trans	-58.3	-46.2	175.4	0	0	0	0	0	112.5	M56 L84 A89 V90	M56-G86 WeakPolarHBondContact O-CA 3.26Å; L84-G86 VanDerWaalsContact C-N 3.27Å; L84-G86 PolarHBondContact O-N 2.87Å; G86-A89 WeakPolarHBondContact O-CB 3.33Å; G86-A89 PolarHBondContact O-N 3.21Å; G86-V90 WeakPolarHBondContact O-CG2 3.14Å; G86-V90 PolarHBondContact O-N 3.5Å
87	Y	82	Confident	78.3	Confident	18 Å²	18	26.3 Å²	26.3	7%	0.071	16%	0.157	C	C	.	.	H	α-helix	trans	-63.8	-45.7	177.4	-72.7	-114.7	0	0	0	110.8	L57 L84 V85 A89 V90 Y91 T405 N406 Y408 M416	L57-Y87 HydrophobicContact CD2-CD2 4.02Å; L57-Y87 HydrophobicContact CD2-CE2 4.27Å; L57-Y87 HydrophobicContact CD2-CG 4.47Å; L84-Y87 HydrophobicContact CD1-CG 4.44Å; L84-Y87 WeakPolarHBondContact O-CB 3.38Å; L84-Y87 PolarHBondContact O-N 2.84Å; V85-Y87 PolarHBondContact O-N 3.47Å; Y87-A89 PolarHBondContact O-N 3.02Å; Y87-V90 PolarHBondContact O-N 3.18Å; Y87-Y91 VanDerWaalsContact O-CD2 3.31Å; Y87-Y91 WeakPolarHBondContact O-CD2 3.38Å; Y87-Y91 PolarHBondContact O-N 3.42Å; Y87-Y91 VanDerWaalsContact O-N 3.09Å; Y87-T405 HydrophobicContact CD1-CG2 3.95Å; Y87-T405 WeakPolarHBondContact CE1-O 3.34Å; Y87-N406 PolarHBondContact OH-ND2 3.05Å; Y87-Y408 HydrophobicContact CE1-CD2 4.17Å; Y87-M416 HydrophobicContact CD1-CE 3.2Å; Y87-M416 HydrophobicContact CD2-CE 3.75Å; Y87-M416 HydrophobicContact CE1-CE 3.31Å; Y87-M416 HydrophobicContact CE1-SD 4.08Å; Y87-M416 HydrophobicContact CE2-CE 3.87Å; Y87-M416 HydrophobicContact CE2-SD 4.4Å; Y87-M416 HydrophobicContact CG-CE 3.42Å; Y87-M416 VanDerWaalsContact CG-CE 3.42Å
88	K	83.2	Confident	80.5	Confident	10 Å²	10	24.3 Å²	24.3	4%	0.043	14%	0.137	C	C	.	.	H	α-helix	trans	-58.8	-34	177.1	-63.6	-164.1	-159.8	173	0	112.2	F71 E75 L84 V85 R92 E145	F71-K88 HydrophobicContact CD1-CB 3.93Å; F71-K88 HydrophobicContact CE1-CB 3.8Å; F71-K88 PolarHBondContact O-NZ 3.02Å; E75-K88 IonicContact OE2-NZ 3.03Å; E75-K88 PolarHBondContact OE2-NZ 3.18Å; L84-K88 HydrophobicContact CD2-CG 4.49Å; L84-K88 HydrophobicContact CG-CG 4.07Å; L84-K88 WeakPolarHBondContact O-CG 3.2Å; L84-K88 PolarHBondContact O-N 2.96Å; V85-K88 PolarHBondContact O-N 3.41Å; K88-R92 PolarHBondContact O-NH1 3.21Å; K88-R92 VanDerWaalsContact O-NH1 3.14Å; K88-E145 WeakPolarHBondContact CD-OE1 3.37Å; K88-E145 WeakPolarHBondContact CE-OE1 3.09Å; K88-E145 IonicContact NZ-OE1 2.84Å; K88-E145 PolarHBondContact NZ-OE1 3.42Å; K88-E145 IonicContact NZ-OE2 2.71Å; K88-E145 PolarHBondContact NZ-OE2 3.17Å
89	A	88.1	Confident	82.8	Confident	0 Å²	0	20.6 Å²	20.6	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-72.8	-43	178.3	0	0	0	0	0	111.4	M56 L65 F71 V85 G86 Y87 Y91 R92 L93 F141	M56-A89 HydrophobicContact CB-CB 4.41Å; M56-A89 HydrophobicContact SD-CB 3.94Å; L65-A89 HydrophobicContact CD1-CB 4.03Å; L65-A89 HydrophobicContact CD2-CB 4.08Å; F71-A89 HydrophobicContact CE1-CB 3.99Å; F71-A89 HydrophobicContact CZ-CB 4.35Å; V85-A89 WeakPolarHBondContact O-CB 3.42Å; V85-A89 PolarHBondContact O-N 3.36Å; G86-A89 WeakPolarHBondContact O-CB 3.33Å; G86-A89 PolarHBondContact O-N 3.21Å; Y87-A89 PolarHBondContact O-N 3.02Å; A89-Y91 VanDerWaalsContact C-N 3.33Å; A89-Y91 PolarHBondContact O-N 3.43Å; A89-R92 PolarHBondContact O-N 2.75Å; A89-L93 PolarHBondContact O-N 2.55Å; A89-F141 HydrophobicContact CB-CE1 4.19Å
90	V	90.6	Very high	84.7	Confident	0 Å²	0	18.4 Å²	18.4	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-58.2	-43.8	175.5	172.6	0	0	0	0	111.4	A53 L57 G86 Y87 R92 L93 C94 M401 L404 T405	A53-V90 HydrophobicContact CB-CG2 4.31Å; L57-V90 HydrophobicContact CD1-CG2 3.98Å; L57-V90 HydrophobicContact CD2-CG2 3.9Å; L57-V90 HydrophobicContact CG-CG2 3.71Å; G86-V90 WeakPolarHBondContact O-CG2 3.14Å; G86-V90 PolarHBondContact O-N 3.5Å; Y87-V90 PolarHBondContact O-N 3.18Å; V90-R92 VanDerWaalsContact C-N 3.31Å; V90-R92 PolarHBondContact O-N 2.95Å; V90-L93 PolarHBondContact O-N 2.95Å; V90-C94 VanDerWaalsContact O-CB 3.28Å; V90-C94 WeakPolarHBondContact O-CB 3.47Å; V90-C94 PolarHBondContact O-N 3.45Å; V90-C94 PolarHBondContact O-SG 3.26Å; V90-C94 VanDerWaalsContact O-SG 3.4Å; V90-M401 HydrophobicContact CG1-CG 4.48Å; V90-L404 HydrophobicContact CG1-CB 4.21Å; V90-L404 HydrophobicContact CG1-CD1 4.42Å; V90-T405 HydrophobicContact CB-CG2 4.29Å; V90-T405 HydrophobicContact CG1-CG2 3.93Å
91	Y	91.1	Very high	86.5	Confident	16 Å²	16	15.6 Å²	15.6	6%	0.063	8%	0.079	C	C	.	.	H	α-helix	trans	-56	-43.7	177.2	-92.3	-106	0	0	0	112.7	Y87 A89 F95 W152 F153 M401 T405	Y87-Y91 VanDerWaalsContact O-CD2 3.31Å; Y87-Y91 WeakPolarHBondContact O-CD2 3.38Å; Y87-Y91 PolarHBondContact O-N 3.42Å; Y87-Y91 VanDerWaalsContact O-N 3.09Å; A89-Y91 VanDerWaalsContact C-N 3.33Å; A89-Y91 PolarHBondContact O-N 3.43Å; Y91-F95 VanDerWaalsContact O-CB 3.22Å; Y91-F95 WeakPolarHBondContact O-CB 3.38Å; Y91-F95 PolarHBondContact O-N 2.85Å; Y91-W152 HydrophobicContact CD1-CB 4.35Å; Y91-W152 AromaticContact CD1-CD1 3.66Å; Y91-W152 HydrophobicContact CD1-CG 4.4Å; Y91-F153 HydrophobicContact CE1-CB 4.27Å; Y91-F153 WeakPolarHBondContact OH-CD2 3.35Å; Y91-M401 HydrophobicContact CD1-CE 4.47Å; Y91-M401 HydrophobicContact CD1-SD 3.81Å; Y91-M401 HydrophobicContact CD2-CG 4.45Å; Y91-M401 HydrophobicContact CE1-CE 4.09Å; Y91-M401 HydrophobicContact CE1-SD 3.97Å; Y91-M401 HydrophobicContact CG-CG 4.47Å; Y91-M401 HydrophobicContact CG-SD 4.07Å; Y91-T405 HydrophobicContact CD2-CG2 3.78Å; Y91-T405 HydrophobicContact CE2-CG2 3.42Å; Y91-T405 VanDerWaalsContact CE2-CG2 3.42Å
92	R	92	Very high	87.9	Confident	2 Å²	2	16.9 Å²	16.9	1%	0.008	8%	0.084	C	C	.	.	H	α-helix	trans	-74.2	-42.9	-178.2	-71.7	164.2	168.4	99.3	-8.5	112.3	K88 A89 V90 F95 G96 A140 F141 I143 E145 F148	K88-R92 PolarHBondContact O-NH1 3.21Å; K88-R92 VanDerWaalsContact O-NH1 3.14Å; A89-R92 PolarHBondContact O-N 2.75Å; V90-R92 VanDerWaalsContact C-N 3.31Å; V90-R92 PolarHBondContact O-N 2.95Å; R92-F95 PolarHBondContact O-N 3.03Å; R92-G96 PolarHBondContact O-N 3.13Å; R92-A140 HydrophobicContact CB-CB 4.44Å; R92-A140 WeakPolarHBondContact CG-O 3.45Å; R92-A140 VanDerWaalsContact O-CB 3.3Å; R92-A140 WeakPolarHBondContact O-CB 3.5Å; R92-F141 HydrophobicContact CB-CD2 4.49Å; R92-F141 HydrophobicContact CB-CE2 4.45Å; R92-F141 HydrophobicContact CB-CZ 4.46Å; R92-I143 PolarHBondContact NE-O 3.36Å; R92-I143 PolarHBondContact NH2-O 2.78Å; R92-E145 VanDerWaalsContact NH2-CG 3.32Å; R92-F148 HydrophobicContact CG-CE1 4.38Å
93	L	94.3	Very high	89.5	Confident	7 Å²	7	17.5 Å²	17.5	4%	0.037	9%	0.087	C	C	.	.	H	α-helix	trans	-59.5	-50.9	174.8	-175.4	94.7	0	0	0	110.9	G49 V52 A53 M56 A89 V90 F95 G96 L97 I137 F141	G49-L93 WeakPolarHBondContact O-CD2 3.39Å; V52-L93 HydrophobicContact CB-CD2 4.37Å; V52-L93 HydrophobicContact CG1-CD1 3.82Å; V52-L93 HydrophobicContact CG1-CD2 4.21Å; A53-L93 HydrophobicContact CB-CD2 3.56Å; M56-L93 HydrophobicContact CE-CD1 3.96Å; M56-L93 HydrophobicContact SD-CB 4.32Å; M56-L93 HydrophobicContact SD-CD1 4.38Å; M56-L93 HydrophobicContact SD-CD2 4.42Å; A89-L93 PolarHBondContact O-N 2.55Å; V90-L93 PolarHBondContact O-N 2.95Å; L93-F95 VanDerWaalsContact C-N 3.34Å; L93-F95 PolarHBondContact O-N 3.02Å; L93-G96 PolarHBondContact O-N 2.94Å; L93-L97 HydrophobicContact CD2-CD1 4.46Å; L93-L97 HydrophobicContact CG-CD1 4.45Å; L93-L97 PolarHBondContact O-N 3.12Å; L93-I137 HydrophobicContact CD1-CG2 3.83Å; L93-F141 HydrophobicContact CB-CE2 4.45Å; L93-F141 HydrophobicContact CB-CZ 4.46Å
94	C	95.5	Very high	91.1	Very high	2 Å²	2	16.3 Å²	16.3	1%	0.014	8%	0.081	C	C	.	.	H	α-helix	trans	-66.7	-34.5	179.5	-70.3	0	0	0	0	112.3	V90 G96 L97 A98 M401	V90-C94 VanDerWaalsContact O-CB 3.28Å; V90-C94 WeakPolarHBondContact O-CB 3.47Å; V90-C94 PolarHBondContact O-N 3.45Å; V90-C94 PolarHBondContact O-SG 3.26Å; V90-C94 VanDerWaalsContact O-SG 3.4Å; C94-G96 VanDerWaalsContact C-N 3.34Å; C94-L97 PolarHBondContact O-N 2.03Å; C94-A98 WeakPolarHBondContact O-CB 3.45Å; C94-A98 PolarHBondContact O-N 2.95Å; C94-M401 HydrophobicContact CB-CB 3.62Å; C94-M401 HydrophobicContact CB-CG 3.84Å; C94-M401 HydrophobicContact CB-SD 4.11Å
95	F	95.6	Very high	92.2	Very high	42 Å²	42	15.5 Å²	15.5	18%	0.184	8%	0.078	C	C	.	.	H	α-helix	trans	-57.9	-47.4	169.9	174.3	-92.7	0	0	0	111.3	Y91 R92 L93 L97 A98 M99 A140 I143 F148 W152	Y91-F95 VanDerWaalsContact O-CB 3.22Å; Y91-F95 WeakPolarHBondContact O-CB 3.38Å; Y91-F95 PolarHBondContact O-N 2.85Å; R92-F95 PolarHBondContact O-N 3.03Å; L93-F95 VanDerWaalsContact C-N 3.34Å; L93-F95 PolarHBondContact O-N 3.02Å; F95-L97 PolarHBondContact O-N 3.45Å; F95-A98 PolarHBondContact O-N 3.5Å; F95-M99 HydrophobicContact CD1-CG 4.18Å; F95-M99 HydrophobicContact CD2-CG 4.23Å; F95-M99 HydrophobicContact CE1-CG 3.79Å; F95-M99 HydrophobicContact CE2-CG 3.83Å; F95-M99 HydrophobicContact CE2-SD 4.11Å; F95-M99 HydrophobicContact CG-CG 4.4Å; F95-M99 HydrophobicContact CZ-CG 3.6Å; F95-M99 HydrophobicContact CZ-SD 4.2Å; F95-M99 WeakPolarHBondContact O-CB 3.3Å; F95-M99 VanDerWaalsContact O-CG 3.32Å; F95-M99 WeakPolarHBondContact O-CG 2.98Å; F95-M99 PolarHBondContact O-N 2.94Å; F95-A140 HydrophobicContact CD1-CB 3.67Å; F95-A140 HydrophobicContact CE1-CB 4.35Å; F95-I143 HydrophobicContact CD1-CD1 3.99Å; F95-I143 HydrophobicContact CE1-CD1 3.71Å; F95-I143 HydrophobicContact CZ-CD1 4.27Å; F95-F148 HydrophobicContact CB-CZ 3.99Å; F95-F148 HydrophobicContact CD1-CZ 4.36Å; F95-F148 AromaticContact CD2-CE2 3.72Å; F95-F148 HydrophobicContact CD2-CE2 3.72Å; F95-F148 AromaticContact CD2-CZ 3.76Å; F95-F148 HydrophobicContact CD2-CZ 3.76Å; F95-F148 AromaticContact CE2-CE2 3.87Å; F95-F148 HydrophobicContact CE2-CE2 3.87Å; F95-F148 HydrophobicContact CE2-CZ 4.35Å; F95-F148 HydrophobicContact CG-CE2 4.13Å; F95-F148 AromaticContact CG-CZ 3.77Å; F95-F148 HydrophobicContact CG-CZ 3.77Å; F95-F148 HydrophobicContact CZ-CE2 4.38Å; F95-W152 HydrophobicContact CB-CZ2 4.05Å; F95-W152 AromaticContact CD2-CD2 3.75Å; F95-W152 HydrophobicContact CD2-CD2 3.75Å; F95-W152 AromaticContact CD2-CE2 3.58Å; F95-W152 AromaticContact CD2-CE3 3.77Å; F95-W152 HydrophobicContact CD2-CE3 3.77Å; F95-W152 AromaticContact CD2-CH2 3.54Å; F95-W152 HydrophobicContact CD2-CH2 3.54Å; F95-W152 AromaticContact CD2-CZ2 3.51Å; F95-W152 HydrophobicContact CD2-CZ2 3.51Å; F95-W152 AromaticContact CD2-CZ3 3.67Å; F95-W152 HydrophobicContact CD2-CZ3 3.67Å; F95-W152 HydrophobicContact CE2-CE3 4.12Å; F95-W152 AromaticContact CE2-CH2 4Å; F95-W152 HydrophobicContact CE2-CH2 4Å; F95-W152 HydrophobicContact CE2-CZ2 4.4Å; F95-W152 AromaticContact CE2-CZ3 3.83Å; F95-W152 HydrophobicContact CE2-CZ3 3.83Å; F95-W152 HydrophobicContact CG-CZ2 4.2Å
96	G	96.3	Very high	93	Very high	0 Å²	0	20.5 Å²	20.5	0%	0	10%	0.104	C	C	.	.	H	α-helix	trans	-61.3	-44.6	178.8	0	0	0	0	0	113.1	R92 L93 C94 F100	R92-G96 PolarHBondContact O-N 3.13Å; L93-G96 PolarHBondContact O-N 2.94Å; C94-G96 VanDerWaalsContact C-N 3.34Å; G96-F100 WeakPolarHBondContact O-CB 3.01Å; G96-F100 PolarHBondContact O-N 2.91Å
97	L	96.6	Very high	93.6	Very high	4 Å²	4	24.5 Å²	24.5	2%	0.021	12%	0.124	C	C	.	.	H	α-helix	trans	-61.8	-45.9	174.3	-70.7	169.1	0	0	0	111.9	F45 L93 C94 F95 M99 F100 Y101 I137	F45-L97 HydrophobicContact CE1-CD2 4.13Å; L93-L97 HydrophobicContact CD2-CD1 4.46Å; L93-L97 HydrophobicContact CG-CD1 4.45Å; L93-L97 PolarHBondContact O-N 3.12Å; C94-L97 PolarHBondContact O-N 2.03Å; F95-L97 PolarHBondContact O-N 3.45Å; L97-M99 PolarHBondContact O-N 3.32Å; L97-F100 WeakPolarHBondContact O-CB 3.5Å; L97-F100 PolarHBondContact O-N 3.34Å; L97-Y101 WeakPolarHBondContact O-CD2 3Å; L97-Y101 PolarHBondContact O-N 3.22Å; L97-I137 HydrophobicContact CD2-CD1 3.91Å; L97-I137 HydrophobicContact CG-CD1 4.09Å
98	A	97.2	Very high	94	Very high	0 Å²	0	23.8 Å²	23.8	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-58.8	-50.2	178.5	0	0	0	0	0	111	C94 F95 F100 Y101 L102 W152 F394 S397 L398	C94-A98 WeakPolarHBondContact O-CB 3.45Å; C94-A98 PolarHBondContact O-N 2.95Å; F95-A98 PolarHBondContact O-N 3.5Å; A98-F100 VanDerWaalsContact C-N 3.29Å; A98-F100 PolarHBondContact O-N 3.4Å; A98-Y101 PolarHBondContact O-N 2.85Å; A98-L102 VanDerWaalsContact O-CB 3.29Å; A98-L102 WeakPolarHBondContact O-CB 3.31Å; A98-L102 PolarHBondContact O-N 3.34Å; A98-W152 HydrophobicContact CB-CH2 4.27Å; A98-W152 HydrophobicContact CB-CZ2 3.92Å; A98-F394 HydrophobicContact CB-CD2 3.77Å; A98-F394 HydrophobicContact CB-CE2 3.89Å; A98-F394 VanDerWaalsContact O-CD2 3.3Å; A98-F394 WeakPolarHBondContact O-CD2 3.24Å; A98-S397 WeakPolarHBondContact CA-OG 3.08Å; A98-S397 WeakPolarHBondContact CB-OG 3.43Å; A98-L398 HydrophobicContact CB-CD2 4.14Å
99	M	96.8	Very high	94.4	Very high	68 Å²	68	27.1 Å²	27.1	34%	0.335	14%	0.138	S	C	.	.	H	α-helix	trans	-62.8	-35.9	179.8	-68.6	-51.5	-58.9	0	0	112.5	F95 L97 L102 L103 I136	F95-M99 HydrophobicContact CD1-CG 4.18Å; F95-M99 HydrophobicContact CD2-CG 4.23Å; F95-M99 HydrophobicContact CE1-CG 3.79Å; F95-M99 HydrophobicContact CE2-CG 3.83Å; F95-M99 HydrophobicContact CE2-SD 4.11Å; F95-M99 HydrophobicContact CG-CG 4.4Å; F95-M99 HydrophobicContact CZ-CG 3.6Å; F95-M99 HydrophobicContact CZ-SD 4.2Å; F95-M99 WeakPolarHBondContact O-CB 3.3Å; F95-M99 VanDerWaalsContact O-CG 3.32Å; F95-M99 WeakPolarHBondContact O-CG 2.98Å; F95-M99 PolarHBondContact O-N 2.94Å; L97-M99 PolarHBondContact O-N 3.32Å; M99-L102 HydrophobicContact CE-CD2 4.26Å; M99-L102 HydrophobicContact SD-CD2 4.25Å; M99-L103 WeakPolarHBondContact O-CB 3.27Å; M99-L103 PolarHBondContact O-N 3.04Å; M99-I136 HydrophobicContact CB-CG2 4.14Å
100	F	97.1	Very high	94.4	Very high	5 Å²	5	35.7 Å²	35.7	2%	0.022	18%	0.176	C	C	.	.	H	α-helix	trans	-62.1	-51.1	174.2	170.4	-103.4	0	0	0	112.3	F45 G96 L97 A98 L102 L103 L104 K129 A133 I136	F45-F100 HydrophobicContact CD1-CE1 4.16Å; F45-F100 HydrophobicContact CE1-CD1 4.16Å; F45-F100 AromaticContact CE1-CE1 3.93Å; F45-F100 HydrophobicContact CE1-CE1 3.93Å; G96-F100 WeakPolarHBondContact O-CB 3.01Å; G96-F100 PolarHBondContact O-N 2.91Å; L97-F100 WeakPolarHBondContact O-CB 3.5Å; L97-F100 PolarHBondContact O-N 3.34Å; A98-F100 VanDerWaalsContact C-N 3.29Å; A98-F100 PolarHBondContact O-N 3.4Å; F100-L102 VanDerWaalsContact C-N 3.33Å; F100-L102 PolarHBondContact O-N 3.4Å; F100-L103 PolarHBondContact O-N 3.3Å; F100-L104 HydrophobicContact CD1-CD1 4.42Å; F100-L104 HydrophobicContact CE1-CD1 3.71Å; F100-L104 HydrophobicContact CE2-CD1 4.01Å; F100-L104 HydrophobicContact CE2-CG 4.37Å; F100-L104 HydrophobicContact CZ-CD1 3.48Å; F100-L104 VanDerWaalsContact CZ-CD1 3.48Å; F100-L104 HydrophobicContact CZ-CG 4.31Å; F100-L104 PolarHBondContact O-N 3.05Å; F100-K129 HydrophobicContact CE2-CB 4.35Å; F100-K129 WeakPolarHBondContact CE2-O 3.4Å; F100-K129 HydrophobicContact CZ-CB 4.15Å; F100-A133 HydrophobicContact CB-CB 4.37Å; F100-A133 HydrophobicContact CD1-CB 4.09Å; F100-A133 HydrophobicContact CD2-CB 3.61Å; F100-A133 HydrophobicContact CE1-CB 4.25Å; F100-A133 HydrophobicContact CE2-CB 3.8Å; F100-A133 HydrophobicContact CG-CB 3.75Å; F100-A133 HydrophobicContact CZ-CB 4.11Å; F100-I136 HydrophobicContact CB-CD1 4.25Å; F100-I136 HydrophobicContact CD2-CD1 4.42Å
101	Y	96.9	Very high	94.2	Very high	0 Å²	0	36.2 Å²	36.2	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-67.4	-34.7	178.3	-72.7	-65.6	0	0	0	112.4	Y42 F45 L46 L97 A98 L104 S105 H390 L393	Y42-Y101 HydrophobicContact CD1-CE1 4.17Å; Y42-Y101 PolarHBondContact O-OH 3.47Å; F45-Y101 WeakPolarHBondContact CD1-OH 3.44Å; L46-Y101 HydrophobicContact CB-CE2 4.31Å; L46-Y101 WeakPolarHBondContact CB-OH 3.41Å; L46-Y101 HydrophobicContact CD1-CE2 3.9Å; L46-Y101 PolarHBondContact N-OH 3.44Å; L97-Y101 WeakPolarHBondContact O-CD2 3Å; L97-Y101 PolarHBondContact O-N 3.22Å; A98-Y101 PolarHBondContact O-N 2.85Å; Y101-L104 PolarHBondContact O-N 3.38Å; Y101-S105 WeakPolarHBondContact O-CB 3.25Å; Y101-S105 PolarHBondContact O-N 3.35Å; Y101-H390 AromaticContact CD1-ND1 3.83Å; Y101-L393 HydrophobicContact CD1-CB 3.62Å; Y101-L393 HydrophobicContact CD1-CD1 3.77Å; Y101-L393 HydrophobicContact CD1-CG 4.37Å; Y101-L393 HydrophobicContact CD2-CB 4.18Å; Y101-L393 HydrophobicContact CE1-CB 3.9Å; Y101-L393 HydrophobicContact CE1-CD1 3.41Å; Y101-L393 VanDerWaalsContact CE1-CD1 3.41Å; Y101-L393 HydrophobicContact CE1-CG 4.3Å; Y101-L393 HydrophobicContact CE2-CB 4.45Å; Y101-L393 HydrophobicContact CG-CB 3.78Å
102	L	96.8	Very high	93.9	Very high	43 Å²	43	41.7 Å²	41.7	23%	0.225	20%	0.203	C	C	.	.	H	α-helix	trans	-63.6	-44.6	174.1	-175.7	62.2	0	0	0	111.3	A98 M99 F100 L104 S105 L106 F394	A98-L102 VanDerWaalsContact O-CB 3.29Å; A98-L102 WeakPolarHBondContact O-CB 3.31Å; A98-L102 PolarHBondContact O-N 3.34Å; M99-L102 HydrophobicContact CE-CD2 4.26Å; M99-L102 HydrophobicContact SD-CD2 4.25Å; F100-L102 VanDerWaalsContact C-N 3.33Å; F100-L102 PolarHBondContact O-N 3.4Å; L102-L104 VanDerWaalsContact C-N 3.35Å; L102-L104 PolarHBondContact O-N 3.19Å; L102-S105 WeakPolarHBondContact O-CB 3.47Å; L102-S105 PolarHBondContact O-N 3.38Å; L102-L106 HydrophobicContact CG-CD1 4.47Å; L102-L106 WeakPolarHBondContact O-CG 3.26Å; L102-L106 PolarHBondContact O-N 2.66Å; L102-F394 HydrophobicContact CB-CD2 3.85Å; L102-F394 HydrophobicContact CB-CE2 4.21Å; L102-F394 HydrophobicContact CB-CG 4.27Å; L102-F394 HydrophobicContact CD1-CD1 4.42Å; L102-F394 HydrophobicContact CD1-CE1 4.5Å; L102-F394 HydrophobicContact CD1-CG 4.43Å; L102-F394 HydrophobicContact CD2-CE2 4.18Å; L102-F394 HydrophobicContact CD2-CZ 4.45Å
103	L	96.2	Very high	93.6	Very high	90 Å²	90	42.4 Å²	42.4	47%	0.471	21%	0.208	S	C	.	.	H	α-helix	trans	-59	-46.5	175.8	-174.1	80.3	0	0	0	111.1	M99 F100 S105 L106 L107	M99-L103 WeakPolarHBondContact O-CB 3.27Å; M99-L103 PolarHBondContact O-N 3.04Å; F100-L103 PolarHBondContact O-N 3.3Å; L103-S105 VanDerWaalsContact C-N 3.34Å; L103-S105 PolarHBondContact O-N 3.05Å; L103-L106 PolarHBondContact O-N 3.23Å; L103-L107 HydrophobicContact CD2-CD1 4.5Å; L103-L107 HydrophobicContact CG-CD1 4.19Å; L103-L107 WeakPolarHBondContact O-CG 3.28Å; L103-L107 PolarHBondContact O-N 3.43Å
104	L	95.1	Very high	93	Very high	7 Å²	7	42.9 Å²	42.9	4%	0.037	21%	0.212	C	C	.	.	H	α-helix	trans	-63.2	-39.5	175.8	-72	-178.3	0	0	0	112.1	Y42 F100 Y101 L102 L106 L107 M108 H390	Y42-L104 HydrophobicContact CE1-CD1 3.77Å; F100-L104 HydrophobicContact CD1-CD1 4.42Å; F100-L104 HydrophobicContact CE1-CD1 3.71Å; F100-L104 HydrophobicContact CE2-CD1 4.01Å; F100-L104 HydrophobicContact CE2-CG 4.37Å; F100-L104 HydrophobicContact CZ-CD1 3.48Å; F100-L104 VanDerWaalsContact CZ-CD1 3.48Å; F100-L104 HydrophobicContact CZ-CG 4.31Å; F100-L104 PolarHBondContact O-N 3.05Å; Y101-L104 PolarHBondContact O-N 3.38Å; L102-L104 VanDerWaalsContact C-N 3.35Å; L102-L104 PolarHBondContact O-N 3.19Å; L104-L106 VanDerWaalsContact C-N 3.32Å; L104-L106 PolarHBondContact O-N 2.93Å; L104-L107 PolarHBondContact O-N 2.72Å; L104-M108 WeakPolarHBondContact O-CB 3.47Å; L104-M108 WeakPolarHBondContact O-CG 3.31Å; L104-M108 PolarHBondContact O-N 3.07Å; L104-H390 HydrophobicContact CB-CB 4.31Å
105	S	94.1	Very high	92.3	Very high	7 Å²	7	47.1 Å²	47.1	5%	0.049	24%	0.242	C	C	.	.	H	α-helix	trans	-57	-47.4	173.6	180	0	0	0	0	111.1	Y101 L102 L103 M108 S387	Y101-S105 WeakPolarHBondContact O-CB 3.25Å; Y101-S105 PolarHBondContact O-N 3.35Å; L102-S105 WeakPolarHBondContact O-CB 3.47Å; L102-S105 PolarHBondContact O-N 3.38Å; L103-S105 VanDerWaalsContact C-N 3.34Å; L103-S105 PolarHBondContact O-N 3.05Å; S105-M108 PolarHBondContact O-N 3.19Å; S105-S387 PolarHBondContact O-OG 3.42Å; S105-S387 VanDerWaalsContact O-OG 3.12Å; S105-S387 PolarHBondContact OG-O 2.93Å; S105-S387 PolarHBondContact OG-OG 2.81Å
106	L	95.4	Very high	91.9	Very high	104 Å²	104	47.3 Å²	47.3	55%	0.545	24%	0.244	S	C	.	.	H	α-helix	trans	-66.2	-39.6	-179.6	-66.1	175.1	0	0	0	112.3	L102 L103 L104 M108 I109	L102-L106 HydrophobicContact CG-CD1 4.47Å; L102-L106 WeakPolarHBondContact O-CG 3.26Å; L102-L106 PolarHBondContact O-N 2.66Å; L103-L106 PolarHBondContact O-N 3.23Å; L104-L106 VanDerWaalsContact C-N 3.32Å; L104-L106 PolarHBondContact O-N 2.93Å; L106-M108 VanDerWaalsContact C-N 3.28Å; L106-M108 PolarHBondContact O-N 2.94Å; L106-I109 HydrophobicContact CD2-CD1 4.05Å; L106-I109 WeakPolarHBondContact O-CG1 3.41Å
107	L	93.9	Very high	91.4	Very high	90 Å²	90	52.7 Å²	52.7	47%	0.471	28%	0.28	S	S	.	.	H	α-helix	trans	-66.5	-30	177.6	-72.5	172.7	0	0	0	113	L103 L104	L103-L107 HydrophobicContact CD2-CD1 4.5Å; L103-L107 HydrophobicContact CG-CD1 4.19Å; L103-L107 WeakPolarHBondContact O-CG 3.28Å; L103-L107 PolarHBondContact O-N 3.43Å; L104-L107 PolarHBondContact O-N 2.72Å
108	M	92.1	Very high	91	Very high	3 Å²	3	57.5 Å²	57.5	2%	0.015	30%	0.297	C	S	.	.	T	Hydrogen-bonded Turn	trans	-92.9	10.1	-176.2	-61.3	-57	140.2	0	0	114.1	L104 S105 L106 K110 V111 R118 V121 H122 Y386	L104-M108 WeakPolarHBondContact O-CB 3.47Å; L104-M108 WeakPolarHBondContact O-CG 3.31Å; L104-M108 PolarHBondContact O-N 3.07Å; S105-M108 PolarHBondContact O-N 3.19Å; L106-M108 VanDerWaalsContact C-N 3.28Å; L106-M108 PolarHBondContact O-N 2.94Å; M108-K110 PolarHBondContact O-N 3Å; M108-V111 PolarHBondContact O-N 3.14Å; M108-V111 HydrophobicContact SD-CG2 4.18Å; M108-R118 WeakPolarHBondContact CE-O 3.3Å; M108-V121 HydrophobicContact CE-CB 3.96Å; M108-V121 HydrophobicContact CE-CG1 3.96Å; M108-H122 HydrophobicContact CE-CB 4.37Å; M108-H122 HydrophobicContact SD-CB 3.87Å; M108-Y386 HydrophobicContact SD-CD2 4.4Å
109	I	90.2	Very high	90.5	Very high	79 Å²	79	57.5 Å²	57.5	41%	0.405	30%	0.297	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.2	128	176.4	-67.2	173.1	0	0	0	110.2	L106 V111 R118	L106-I109 HydrophobicContact CD2-CD1 4.05Å; L106-I109 WeakPolarHBondContact O-CG1 3.41Å; I109-V111 VanDerWaalsContact C-N 3.32Å; I109-V111 PolarHBondContact O-N 2.86Å; I109-R118 PolarHBondContact O-NH1 3.36Å
110	K	88.2	Confident	90	Very high	181 Å²	181	56.4 Å²	56.4	79%	0.787	30%	0.299	S	S	*	.	T	Hydrogen-bonded Turn	trans	56.8	37.8	178.1	-62.4	177.2	175.4	-176.5	0	113.9	M108 R118	M108-K110 PolarHBondContact O-N 3Å; K110-R118 PolarHBondContact O-NH2 3.08Å; K110-R118 VanDerWaalsContact O-NH2 3.09Å
111	V	87.4	Confident	89.6	Confident	10 Å²	10	58.9 Å²	58.9	6%	0.061	32%	0.315	C	S	.	.			trans	-78.6	123.8	162.3	175.4	0	0	0	0	107.6	M108 I109 D116 R118 A119 V382 Y386	M108-V111 PolarHBondContact O-N 3.14Å; M108-V111 HydrophobicContact SD-CG2 4.18Å; I109-V111 VanDerWaalsContact C-N 3.32Å; I109-V111 PolarHBondContact O-N 2.86Å; V111-D116 HydrophobicContact CG1-CB 4.19Å; V111-R118 HydrophobicContact CG2-CB 3.97Å; V111-A119 HydrophobicContact CG1-CB 4.05Å; V111-V382 HydrophobicContact CG1-CG1 4.4Å; V111-Y386 HydrophobicContact CB-CD2 4.16Å; V111-Y386 HydrophobicContact CG1-CD2 3.77Å; V111-Y386 HydrophobicContact CG1-CE2 3.88Å
112	K	84.8	Confident	89.3	Confident	132 Å²	132	58.9 Å²	58.9	57%	0.574	32%	0.315	S	S	*	.			trans	-108	-23.4	-175	-72.2	-165.5	172.9	-165.1	0	113.5	D116 E350 G381 V382	K112-D116 PolarHBondContact N-OD2 3.35Å; K112-E350 IonicContact NZ-OE1 2.77Å; K112-E350 PolarHBondContact NZ-OE1 3.07Å; K112-G381 WeakPolarHBondContact O-CA 3.3Å; K112-V382 PolarHBondContact O-N 2.87Å
113	S	84.4	Confident	88.7	Confident	16 Å²	16	57.2 Å²	57.2	11%	0.112	31%	0.306	C	S	.	.	S	Bend	trans	-145	155.2	-178.1	158.5	0	0	0	0	111.3	S115 D116 R379	S113-S115 PolarHBondContact O-N 3.49Å; S113-S115 PolarHBondContact OG-N 3.27Å; S113-S115 PolarHBondContact OG-OG 3.18Å; S113-D116 WeakPolarHBondContact O-CB 3.46Å; S113-D116 PolarHBondContact O-N 3.37Å; S113-R379 PolarHBondContact OG-O 3.43Å
114	S	82.6	Confident	88.1	Confident	18 Å²	18	53 Å²	53	13%	0.126	28%	0.284	C	S	.	.	T	Hydrogen-bonded Turn	trans	-63.1	-15.9	172.6	78.4	0	0	0	0	113.4	D116 A119 D376 E378 R379	S114-D116 VanDerWaalsContact C-N 3.3Å; S114-A119 WeakPolarHBondContact O-CB 3.5Å; S114-D376 PolarHBondContact OG-OD1 3.41Å; S114-D376 PolarHBondContact OG-OD2 3.19Å; S114-E378 WeakPolarHBondContact CB-O 3.28Å; S114-E378 PolarHBondContact N-O 2.92Å; S114-E378 PolarHBondContact OG-O 2.91Å; S114-R379 VanDerWaalsContact OG-CA 3.28Å; S114-R379 WeakPolarHBondContact OG-CA 3.38Å; S114-R379 PolarHBondContact OG-N 3.42Å
115	S	80.8	Confident	87.7	Confident	91 Å²	91	56.3 Å²	56.3	64%	0.636	30%	0.299	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.6	-15.5	176.3	69.4	0	0	0	0	113.7	S113	S113-S115 PolarHBondContact O-N 3.49Å; S113-S115 PolarHBondContact OG-N 3.27Å; S113-S115 PolarHBondContact OG-OG 3.18Å
116	D	86.5	Confident	87.3	Confident	45 Å²	45	56 Å²	56	24%	0.241	30%	0.297	C	S	.	.	S	Bend	trans	-61.9	135.8	175.8	-80.4	-26.8	0	0	0	109.8	V111 K112 S113 S114 R118 A119 A120	V111-D116 HydrophobicContact CG1-CB 4.19Å; K112-D116 PolarHBondContact N-OD2 3.35Å; S113-D116 WeakPolarHBondContact O-CB 3.46Å; S113-D116 PolarHBondContact O-N 3.37Å; S114-D116 VanDerWaalsContact C-N 3.3Å; D116-R118 PolarHBondContact O-N 2.9Å; D116-R118 IonicContact OD2-NH2 3.86Å; D116-A119 HydrophobicContact CB-CB 4.34Å; D116-A119 WeakPolarHBondContact O-CA 3.4Å; D116-A119 VanDerWaalsContact O-CB 3.28Å; D116-A119 WeakPolarHBondContact O-CB 3.45Å; D116-A119 PolarHBondContact O-N 3.34Å; D116-A120 PolarHBondContact O-N 3.27Å
117	P	85.7	Confident	86.9	Confident	114 Å²	114	56.1 Å²	56.1	74%	0.74	29%	0.293	S	S	*	.	H	α-helix	trans	-55.8	-27.9	177.4	-27	34.1	0	0	0	113.5	A120	P117-A120 WeakPolarHBondContact O-CB 3.42Å; P117-A120 PolarHBondContact O-N 3.02Å
118	R	89.7	Confident	86.7	Confident	104 Å²	104	58 Å²	58	39%	0.392	30%	0.297	S	S	.	.	H	α-helix	trans	-70.7	-31.6	175.4	-63.7	176.3	-67.4	159.3	6	112.2	M108 I109 K110 V111 D116 A120 V121 H122	M108-R118 WeakPolarHBondContact CE-O 3.3Å; I109-R118 PolarHBondContact O-NH1 3.36Å; K110-R118 PolarHBondContact O-NH2 3.08Å; K110-R118 VanDerWaalsContact O-NH2 3.09Å; V111-R118 HydrophobicContact CG2-CB 3.97Å; D116-R118 PolarHBondContact O-N 2.9Å; D116-R118 IonicContact OD2-NH2 3.86Å; R118-A120 VanDerWaalsContact C-N 3.26Å; R118-A120 PolarHBondContact O-N 3.25Å; R118-V121 WeakPolarHBondContact O-CA 3.4Å; R118-V121 WeakPolarHBondContact O-CB 3.36Å; R118-V121 PolarHBondContact O-N 2.91Å; R118-V121 VanDerWaalsContact O-N 3.07Å; R118-H122 PolarHBondContact O-N 3.31Å; R118-H122 VanDerWaalsContact O-N 3.07Å
119	A	86.7	Confident	86.7	Confident	0 Å²	0	58.4 Å²	58.4	0%	0	30%	0.299	C	S	.	.	H	α-helix	trans	-67.3	-28.1	174.4	0	0	0	0	0	112.1	V111 S114 D116 V121 H122 N123 Y386	V111-A119 HydrophobicContact CG1-CB 4.05Å; S114-A119 WeakPolarHBondContact O-CB 3.5Å; D116-A119 HydrophobicContact CB-CB 4.34Å; D116-A119 WeakPolarHBondContact O-CA 3.4Å; D116-A119 VanDerWaalsContact O-CB 3.28Å; D116-A119 WeakPolarHBondContact O-CB 3.45Å; D116-A119 PolarHBondContact O-N 3.34Å; A119-V121 VanDerWaalsContact C-N 3.27Å; A119-V121 PolarHBondContact O-N 2.9Å; A119-H122 WeakPolarHBondContact O-CA 3.34Å; A119-H122 WeakPolarHBondContact O-CB 3.22Å; A119-H122 PolarHBondContact O-N 2.9Å; A119-N123 PolarHBondContact O-N 3.3Å; A119-N123 PolarHBondContact O-ND2 3.45Å; A119-Y386 HydrophobicContact CB-CE2 3.94Å
120	A	85.3	Confident	86.7	Confident	46 Å²	46	56.5 Å²	56.5	38%	0.38	29%	0.288	S	S	.	.	H	α-helix	trans	-61.8	-37.5	169.7	0	0	0	0	0	111.6	D116 P117 R118 G124 F125	D116-A120 PolarHBondContact O-N 3.27Å; P117-A120 WeakPolarHBondContact O-CB 3.42Å; P117-A120 PolarHBondContact O-N 3.02Å; R118-A120 VanDerWaalsContact C-N 3.26Å; R118-A120 PolarHBondContact O-N 3.25Å; A120-G124 WeakPolarHBondContact O-CA 3.47Å; A120-G124 PolarHBondContact O-N 3.03Å; A120-F125 HydrophobicContact CB-CE2 4.42Å
121	V	88.8	Confident	86.9	Confident	57 Å²	57	50 Å²	50	35%	0.345	27%	0.268	S	S	.	.	H	α-helix	trans	-66.8	-36.4	169.4	-179.2	0	0	0	0	110.4	M108 R118 A119 K129	M108-V121 HydrophobicContact CE-CB 3.96Å; M108-V121 HydrophobicContact CE-CG1 3.96Å; R118-V121 WeakPolarHBondContact O-CA 3.4Å; R118-V121 WeakPolarHBondContact O-CB 3.36Å; R118-V121 PolarHBondContact O-N 2.91Å; R118-V121 VanDerWaalsContact O-N 3.07Å; A119-V121 VanDerWaalsContact C-N 3.27Å; A119-V121 PolarHBondContact O-N 2.9Å; V121-K129 WeakPolarHBondContact O-CE 3.31Å; V121-K129 PolarHBondContact O-NZ 3.22Å
122	H	90	Very high	87.2	Confident	0 Å²	0	51.7 Å²	51.7	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-65.3	-48.2	176.5	-172.5	78.8	0	0	0	113.3	T38 Y42 M108 R118 A119 K129 Y384 Y386 H390	T38-H122 WeakPolarHBondContact CG2-O 3.3Å; Y42-H122 AromaticContact CE2-CE1 3.84Å; Y42-H122 PolarHBondContact OH-O 3.08Å; M108-H122 HydrophobicContact CE-CB 4.37Å; M108-H122 HydrophobicContact SD-CB 3.87Å; R118-H122 PolarHBondContact O-N 3.31Å; R118-H122 VanDerWaalsContact O-N 3.07Å; A119-H122 WeakPolarHBondContact O-CA 3.34Å; A119-H122 WeakPolarHBondContact O-CB 3.22Å; A119-H122 PolarHBondContact O-N 2.9Å; H122-K129 PolarHBondContact O-NZ 3.47Å; H122-Y384 AromaticContact NE2-CZ 3.85Å; H122-Y384 PolarHBondContact NE2-OH 2.87Å; H122-Y386 HydrophobicContact CB-CD2 3.81Å; H122-Y386 HydrophobicContact CB-CE2 3.85Å; H122-Y386 AromaticContact CD2-CD2 3.81Å; H122-Y386 AromaticContact CD2-CE1 3.88Å; H122-Y386 AromaticContact CD2-CE2 3.69Å; H122-Y386 AromaticContact CD2-CG 3.95Å; H122-Y386 AromaticContact CD2-CZ 3.71Å; H122-Y386 AromaticContact CE1-CG 3.98Å; H122-Y386 AromaticContact CG-CD2 3.6Å; H122-Y386 AromaticContact CG-CE2 3.8Å; H122-Y386 AromaticContact CG-CG 3.95Å; H122-Y386 AromaticContact ND1-CD2 3.98Å; H122-Y386 AromaticContact ND1-CG 3.95Å; H122-Y386 AromaticContact NE2-CD1 3.86Å; H122-H390 AromaticContact CE1-CD2 3.87Å; H122-H390 AromaticContact CE1-NE2 3.21Å; H122-H390 PolarHBondContact CE1-NE2 3.04Å; H122-H390 AromaticContact ND1-CD2 3.77Å; H122-H390 AromaticContact ND1-NE2 3.09Å; H122-H390 PolarHBondContact ND1-NE2 3.4Å
123	N	85.8	Confident	87.7	Confident	7 Å²	7	45.4 Å²	45.4	4%	0.037	26%	0.256	C	S	.	.	H	α-helix	trans	-92.7	-17.3	-169.4	-69.5	-46.9	0	0	0	114.8	T38 A119 W126 Y386	T38-N123 PolarHBondContact OG1-OD1 2.88Å; T38-N123 VanDerWaalsContact OG1-OD1 3.05Å; A119-N123 PolarHBondContact O-N 3.3Å; A119-N123 PolarHBondContact O-ND2 3.45Å; N123-W126 PolarHBondContact O-NE1 3.32Å; N123-Y386 PolarHBondContact ND2-OH 3.44Å
124	G	83.4	Confident	88.1	Confident	2 Å²	2	49 Å²	49	2%	0.021	27%	0.273	C	S	.	.	S	Bend	trans	-126.8	-160.8	-175.3	0	0	0	0	0	114.2	A120 W126 K129	A120-G124 WeakPolarHBondContact O-CA 3.47Å; A120-G124 PolarHBondContact O-N 3.03Å; G124-W126 VanDerWaalsContact C-N 3.28Å; G124-W126 PolarHBondContact O-N 3.41Å; G124-W126 VanDerWaalsContact O-N 3.17Å; G124-K129 WeakPolarHBondContact O-CE 3.02Å; G124-K129 PolarHBondContact O-NZ 3.17Å
125	F	86	Confident	88.7	Confident	77 Å²	77	51 Å²	51	34%	0.338	29%	0.29	S	S	.	.			trans	50.6	39.7	175.3	-60.1	-80.9	0	0	0	115	S20 A120 F127 F128 K129	S20-F125 VanDerWaalsContact CB-CE1 3.49Å; A120-F125 HydrophobicContact CB-CE2 4.42Å; F125-F127 PolarHBondContact O-N 3.17Å; F125-F128 HydrophobicContact CB-CD2 4.33Å; F125-F128 AromaticContact CD1-CD2 3.94Å; F125-F128 HydrophobicContact CD1-CD2 3.94Å; F125-F128 HydrophobicContact CD1-CE2 4.28Å; F125-F128 PolarHBondContact O-N 3.08Å; F125-K129 WeakPolarHBondContact O-CG 3.4Å; F125-K129 PolarHBondContact O-N 3.48Å; F125-K129 VanDerWaalsContact O-N 3.16Å
126	W	86.2	Confident	89.4	Confident	1 Å²	1	49.1 Å²	49.1	0%	0.004	27%	0.272	C	S	.	.	H	α-helix	trans	-58.4	-44.2	-173.9	-67.5	103.4	0	0	0	113.5	L17 T38 I41 Y42 N123 G124 F128 K129 F130	L17-W126 HydrophobicContact CD2-CB 3.62Å; L17-W126 HydrophobicContact CD2-CG 4.07Å; T38-W126 HydrophobicContact CG2-CH2 3.89Å; T38-W126 HydrophobicContact CG2-CZ2 3.98Å; I41-W126 HydrophobicContact CB-CE3 4.39Å; I41-W126 HydrophobicContact CB-CH2 3.54Å; I41-W126 HydrophobicContact CB-CZ2 4.03Å; I41-W126 HydrophobicContact CB-CZ3 3.76Å; I41-W126 HydrophobicContact CD1-CD2 4.44Å; I41-W126 HydrophobicContact CD1-CH2 4.04Å; I41-W126 HydrophobicContact CD1-CZ2 3.57Å; I41-W126 HydrophobicContact CG1-CH2 4.39Å; I41-W126 HydrophobicContact CG1-CZ2 4.4Å; I41-W126 HydrophobicContact CG2-CD2 4.02Å; I41-W126 HydrophobicContact CG2-CE3 3.46Å; I41-W126 VanDerWaalsContact CG2-CE3 3.46Å; I41-W126 HydrophobicContact CG2-CH2 3.55Å; I41-W126 HydrophobicContact CG2-CZ2 4.09Å; I41-W126 HydrophobicContact CG2-CZ3 3.21Å; Y42-W126 HydrophobicContact CD1-CZ3 4.04Å; Y42-W126 AromaticContact CD2-CH2 3.99Å; Y42-W126 HydrophobicContact CD2-CH2 3.99Å; Y42-W126 HydrophobicContact CD2-CZ3 4.29Å; Y42-W126 HydrophobicContact CE1-CH2 4.36Å; Y42-W126 AromaticContact CE1-CZ3 3.83Å; Y42-W126 HydrophobicContact CE1-CZ3 3.83Å; Y42-W126 AromaticContact CE2-CH2 3.77Å; Y42-W126 HydrophobicContact CE2-CH2 3.77Å; Y42-W126 HydrophobicContact CE2-CZ3 4.1Å; Y42-W126 HydrophobicContact CG-CH2 4.37Å; Y42-W126 HydrophobicContact CG-CZ3 4.26Å; Y42-W126 AromaticContact CZ-CH2 3.96Å; Y42-W126 AromaticContact CZ-CZ3 3.85Å; N123-W126 PolarHBondContact O-NE1 3.32Å; G124-W126 VanDerWaalsContact C-N 3.28Å; G124-W126 PolarHBondContact O-N 3.41Å; G124-W126 VanDerWaalsContact O-N 3.17Å; W126-F128 PolarHBondContact O-N 2.94Å; W126-K129 HydrophobicContact CE3-CD 4.26Å; W126-K129 WeakPolarHBondContact O-CB 3.28Å; W126-K129 PolarHBondContact O-N 3Å; W126-F130 HydrophobicContact CB-CE2 4.36Å; W126-F130 HydrophobicContact CE3-CE1 4.17Å; W126-F130 AromaticContact CE3-CZ 3.85Å; W126-F130 HydrophobicContact CE3-CZ 3.85Å; W126-F130 HydrophobicContact CZ3-CZ 4.48Å; W126-F130 WeakPolarHBondContact O-CD2 3.44Å; W126-F130 WeakPolarHBondContact O-CG 3.24Å; W126-F130 PolarHBondContact O-N 3.38Å
127	F	86.3	Confident	89.8	Confident	105 Å²	105	48.1 Å²	48.1	46%	0.461	27%	0.267	S	S	.	.	H	α-helix	trans	-57.2	-49	177.8	175.2	-95.4	0	0	0	112.6	L17 F125 K129 F130 A131	L17-F127 WeakPolarHBondContact O-CB 3.28Å; L17-F127 PolarHBondContact O-N 2.92Å; F125-F127 PolarHBondContact O-N 3.17Å; F127-K129 VanDerWaalsContact C-N 3.3Å; F127-K129 PolarHBondContact O-N 3.21Å; F127-F130 PolarHBondContact O-N 3.34Å; F127-A131 WeakPolarHBondContact O-CB 3.44Å; F127-A131 PolarHBondContact O-N 2.86Å
128	F	89.5	Confident	90.2	Very high	129 Å²	129	47.2 Å²	47.2	57%	0.566	26%	0.255	S	S	*	.	H	α-helix	trans	-64.7	-36	-179.7	-66.4	-72.2	0	0	0	112.1	F125 W126 A132	F125-F128 HydrophobicContact CB-CD2 4.33Å; F125-F128 AromaticContact CD1-CD2 3.94Å; F125-F128 HydrophobicContact CD1-CD2 3.94Å; F125-F128 HydrophobicContact CD1-CE2 4.28Å; F125-F128 PolarHBondContact O-N 3.08Å; W126-F128 PolarHBondContact O-N 2.94Å; F128-A132 VanDerWaalsContact O-CB 3.29Å; F128-A132 WeakPolarHBondContact O-CB 3.27Å; F128-A132 PolarHBondContact O-N 3.42Å
129	K	91.5	Very high	90.3	Very high	12 Å²	12	44.1 Å²	44.1	5%	0.052	26%	0.256	C	S	.	.	H	α-helix	trans	-64.7	-48.1	174.4	-69.3	170.8	-176.1	165.4	0	112.5	Y42 F100 V121 H122 G124 F125 W126 F127 A131 A132 A133	Y42-K129 HydrophobicContact CE1-CD 4.29Å; Y42-K129 VanDerWaalsContact OH-CE 3.26Å; Y42-K129 WeakPolarHBondContact OH-CE 3.38Å; Y42-K129 PolarHBondContact OH-NZ 2.9Å; F100-K129 HydrophobicContact CE2-CB 4.35Å; F100-K129 WeakPolarHBondContact CE2-O 3.4Å; F100-K129 HydrophobicContact CZ-CB 4.15Å; V121-K129 WeakPolarHBondContact O-CE 3.31Å; V121-K129 PolarHBondContact O-NZ 3.22Å; H122-K129 PolarHBondContact O-NZ 3.47Å; G124-K129 WeakPolarHBondContact O-CE 3.02Å; G124-K129 PolarHBondContact O-NZ 3.17Å; F125-K129 WeakPolarHBondContact O-CG 3.4Å; F125-K129 PolarHBondContact O-N 3.48Å; F125-K129 VanDerWaalsContact O-N 3.16Å; W126-K129 HydrophobicContact CE3-CD 4.26Å; W126-K129 WeakPolarHBondContact O-CB 3.28Å; W126-K129 PolarHBondContact O-N 3Å; F127-K129 VanDerWaalsContact C-N 3.3Å; F127-K129 PolarHBondContact O-N 3.21Å; K129-A131 VanDerWaalsContact C-N 3.33Å; K129-A132 PolarHBondContact O-N 2.88Å; K129-A133 WeakPolarHBondContact O-CB 3.34Å; K129-A133 PolarHBondContact O-N 3.4Å
130	F	90.2	Very high	90.6	Very high	39 Å²	39	44.3 Å²	44.3	17%	0.171	26%	0.257	C	S	.	.	H	α-helix	trans	-66.2	-38.9	-179.7	-64.1	-26.3	0	0	0	111.3	L17 I41 F45 W126 F127 A133 I134	L17-F130 HydrophobicContact CD2-CD2 4.46Å; L17-F130 HydrophobicContact CD2-CE2 3.67Å; L17-F130 HydrophobicContact CD2-CZ 4.5Å; I41-F130 HydrophobicContact CG2-CZ 3.9Å; F45-F130 HydrophobicContact CB-CE1 3.83Å; F45-F130 HydrophobicContact CB-CZ 4.38Å; F45-F130 HydrophobicContact CD1-CD1 4.29Å; F45-F130 HydrophobicContact CD1-CE1 4.18Å; F45-F130 AromaticContact CD2-CD1 3.48Å; F45-F130 HydrophobicContact CD2-CD1 3.48Å; F45-F130 VanDerWaalsContact CD2-CD1 3.48Å; F45-F130 AromaticContact CD2-CE1 3.43Å; F45-F130 HydrophobicContact CD2-CE1 3.43Å; F45-F130 VanDerWaalsContact CD2-CE1 3.43Å; F45-F130 HydrophobicContact CD2-CG 4.28Å; F45-F130 HydrophobicContact CD2-CZ 4.17Å; F45-F130 HydrophobicContact CE1-CD1 4.36Å; F45-F130 HydrophobicContact CE2-CB 4.45Å; F45-F130 AromaticContact CE2-CD1 3.56Å; F45-F130 HydrophobicContact CE2-CD1 3.56Å; F45-F130 HydrophobicContact CE2-CE1 4.03Å; F45-F130 HydrophobicContact CE2-CG 4.16Å; F45-F130 AromaticContact CG-CD1 3.88Å; F45-F130 HydrophobicContact CG-CD1 3.88Å; F45-F130 AromaticContact CG-CE1 3.53Å; F45-F130 HydrophobicContact CG-CE1 3.53Å; F45-F130 HydrophobicContact CG-CZ 4.41Å; F45-F130 HydrophobicContact CZ-CD1 4.03Å; W126-F130 HydrophobicContact CB-CE2 4.36Å; W126-F130 HydrophobicContact CE3-CE1 4.17Å; W126-F130 AromaticContact CE3-CZ 3.85Å; W126-F130 HydrophobicContact CE3-CZ 3.85Å; W126-F130 HydrophobicContact CZ3-CZ 4.48Å; W126-F130 WeakPolarHBondContact O-CD2 3.44Å; W126-F130 WeakPolarHBondContact O-CG 3.24Å; W126-F130 PolarHBondContact O-N 3.38Å; F127-F130 PolarHBondContact O-N 3.34Å; F130-A133 PolarHBondContact O-N 3.36Å; F130-I134 WeakPolarHBondContact O-CB 3.24Å; F130-I134 VanDerWaalsContact O-CG1 3.26Å; F130-I134 WeakPolarHBondContact O-CG1 3.5Å; F130-I134 PolarHBondContact O-N 3.48Å
131	A	92.4	Very high	90.8	Very high	45 Å²	45	43.6 Å²	43.6	37%	0.372	25%	0.245	S	C	.	.	H	α-helix	trans	-60.5	-45.4	171.8	0	0	0	0	0	111.8	F127 K129 I134 A135	F127-A131 WeakPolarHBondContact O-CB 3.44Å; F127-A131 PolarHBondContact O-N 2.86Å; K129-A131 VanDerWaalsContact C-N 3.33Å; A131-I134 PolarHBondContact O-N 2.89Å; A131-A135 WeakPolarHBondContact O-CB 3.43Å; A131-A135 PolarHBondContact O-N 3.42Å
132	A	94.1	Very high	90.7	Very high	45 Å²	45	48.5 Å²	48.5	37%	0.372	26%	0.262	S	S	.	.	H	α-helix	trans	-62.2	-43.7	176.2	0	0	0	0	0	112.1	F128 K129 A135 I136	F128-A132 VanDerWaalsContact O-CB 3.29Å; F128-A132 WeakPolarHBondContact O-CB 3.27Å; F128-A132 PolarHBondContact O-N 3.42Å; K129-A132 PolarHBondContact O-N 2.88Å; A132-A135 PolarHBondContact O-N 3.32Å; A132-I136 VanDerWaalsContact O-CG1 3.27Å; A132-I136 WeakPolarHBondContact O-CG1 3.44Å; A132-I136 PolarHBondContact O-N 3.26Å
133	A	94.9	Very high	90.6	Very high	1 Å²	1	50.5 Å²	50.5	1%	0.008	27%	0.272	C	S	.	.	H	α-helix	trans	-61	-46.7	176.9	0	0	0	0	0	111.9	F45 F100 K129 F130 A135 I136 I137	F45-A133 HydrophobicContact CE1-CB 3.64Å; F45-A133 HydrophobicContact CZ-CB 3.46Å; F45-A133 VanDerWaalsContact CZ-CB 3.46Å; F100-A133 HydrophobicContact CB-CB 4.37Å; F100-A133 HydrophobicContact CD1-CB 4.09Å; F100-A133 HydrophobicContact CD2-CB 3.61Å; F100-A133 HydrophobicContact CE1-CB 4.25Å; F100-A133 HydrophobicContact CE2-CB 3.8Å; F100-A133 HydrophobicContact CG-CB 3.75Å; F100-A133 HydrophobicContact CZ-CB 4.11Å; K129-A133 WeakPolarHBondContact O-CB 3.34Å; K129-A133 PolarHBondContact O-N 3.4Å; F130-A133 PolarHBondContact O-N 3.36Å; A133-A135 VanDerWaalsContact C-N 3.33Å; A133-A135 PolarHBondContact O-N 3.13Å; A133-I136 PolarHBondContact O-N 2.87Å; A133-I137 VanDerWaalsContact O-CG1 3.28Å; A133-I137 WeakPolarHBondContact O-CG1 3.47Å; A133-I137 PolarHBondContact O-N 2.92Å
134	I	93.9	Very high	90.2	Very high	92 Å²	92	54.9 Å²	54.9	47%	0.472	30%	0.301	S	S	.	.	H	α-helix	trans	-62	-41.9	176.7	-68.9	166.1	0	0	0	110.7	F130 A131 I136 I137 I138	F130-I134 WeakPolarHBondContact O-CB 3.24Å; F130-I134 VanDerWaalsContact O-CG1 3.26Å; F130-I134 WeakPolarHBondContact O-CG1 3.5Å; F130-I134 PolarHBondContact O-N 3.48Å; A131-I134 PolarHBondContact O-N 2.89Å; I134-I136 PolarHBondContact O-N 3.25Å; I134-I137 PolarHBondContact O-N 3.35Å; I134-I138 HydrophobicContact CG2-CD1 3.75Å; I134-I138 HydrophobicContact CG2-CG1 4.34Å; I134-I138 VanDerWaalsContact O-CG1 3.31Å; I134-I138 WeakPolarHBondContact O-CG1 3.36Å; I134-I138 PolarHBondContact O-N 2.99Å
135	A	95.5	Very high	89.6	Confident	58 Å²	58	57.4 Å²	57.4	48%	0.479	31%	0.313	S	S	.	.	H	α-helix	trans	-62.4	-42.6	177.1	0	0	0	0	0	112.3	A131 A132 A133 I138 G139	A131-A135 WeakPolarHBondContact O-CB 3.43Å; A131-A135 PolarHBondContact O-N 3.42Å; A132-A135 PolarHBondContact O-N 3.32Å; A133-A135 VanDerWaalsContact C-N 3.33Å; A133-A135 PolarHBondContact O-N 3.13Å; A135-I138 PolarHBondContact O-N 3.38Å; A135-G139 PolarHBondContact O-N 2.95Å
136	I	96.1	Very high	89.1	Confident	52 Å²	52	55.8 Å²	55.8	27%	0.267	32%	0.318	S	S	.	.	H	α-helix	trans	-63.4	-43.2	175.2	-65.9	165.6	0	0	0	110.5	M99 F100 A132 A133 I134 G139 A140	M99-I136 HydrophobicContact CB-CG2 4.14Å; F100-I136 HydrophobicContact CB-CD1 4.25Å; F100-I136 HydrophobicContact CD2-CD1 4.42Å; A132-I136 VanDerWaalsContact O-CG1 3.27Å; A132-I136 WeakPolarHBondContact O-CG1 3.44Å; A132-I136 PolarHBondContact O-N 3.26Å; A133-I136 PolarHBondContact O-N 2.87Å; I134-I136 PolarHBondContact O-N 3.25Å; I136-G139 PolarHBondContact O-N 3.26Å; I136-A140 PolarHBondContact O-N 3.45Å
137	I	94.7	Very high	88.9	Confident	24 Å²	24	61.5 Å²	61.5	12%	0.123	35%	0.353	C	S	.	.	H	α-helix	trans	-60.1	-50.9	176.4	-70.7	165.5	0	0	0	110.4	L93 L97 A133 I134 G139 A140 F141	L93-I137 HydrophobicContact CD1-CG2 3.83Å; L97-I137 HydrophobicContact CD2-CD1 3.91Å; L97-I137 HydrophobicContact CG-CD1 4.09Å; A133-I137 VanDerWaalsContact O-CG1 3.28Å; A133-I137 WeakPolarHBondContact O-CG1 3.47Å; A133-I137 PolarHBondContact O-N 2.92Å; I134-I137 PolarHBondContact O-N 3.35Å; I137-G139 VanDerWaalsContact C-N 3.28Å; I137-G139 PolarHBondContact O-N 3.26Å; I137-A140 WeakPolarHBondContact O-CA 3.44Å; I137-A140 VanDerWaalsContact O-CB 3.28Å; I137-A140 WeakPolarHBondContact O-CB 3.23Å; I137-A140 PolarHBondContact O-N 3.49Å; I137-F141 HydrophobicContact CG2-CD2 4.25Å; I137-F141 HydrophobicContact CG2-CE2 3.91Å; I137-F141 VanDerWaalsContact O-CD2 3.28Å; I137-F141 WeakPolarHBondContact O-CD2 3.29Å; I137-F141 PolarHBondContact O-N 3.35Å
138	I	92.8	Very high	88.9	Confident	95 Å²	95	58.1 Å²	58.1	49%	0.487	34%	0.338	S	S	.	.	H	α-helix	trans	-57.8	-44.3	177.6	-68.7	168	0	0	0	110.3	I134 A135 A140 F141 F142	I134-I138 HydrophobicContact CG2-CD1 3.75Å; I134-I138 HydrophobicContact CG2-CG1 4.34Å; I134-I138 VanDerWaalsContact O-CG1 3.31Å; I134-I138 WeakPolarHBondContact O-CG1 3.36Å; I134-I138 PolarHBondContact O-N 2.99Å; A135-I138 PolarHBondContact O-N 3.38Å; I138-A140 VanDerWaalsContact C-N 3.28Å; I138-A140 PolarHBondContact O-N 3.48Å; I138-F141 WeakPolarHBondContact O-CB 3.4Å; I138-F141 PolarHBondContact O-N 3.43Å; I138-F141 VanDerWaalsContact O-N 3.08Å; I138-F142 HydrophobicContact CG2-CE2 3.96Å; I138-F142 VanDerWaalsContact O-CD2 3.25Å; I138-F142 WeakPolarHBondContact O-CD2 3.27Å
139	G	92.8	Very high	88.6	Confident	40 Å²	40	52.5 Å²	52.5	41%	0.412	31%	0.314	S	S	.	.	H	α-helix	trans	-57.6	-38.1	174.5	0	0	0	0	0	113.2	A135 I136 I137 F141 F142	A135-G139 PolarHBondContact O-N 2.95Å; I136-G139 PolarHBondContact O-N 3.26Å; I137-G139 VanDerWaalsContact C-N 3.28Å; I137-G139 PolarHBondContact O-N 3.26Å; G139-F141 VanDerWaalsContact C-N 3.26Å; G139-F141 PolarHBondContact O-N 2.88Å; G139-F142 PolarHBondContact O-N 2.82Å
140	A	92.6	Very high	88.2	Confident	3 Å²	3	53.9 Å²	53.9	3%	0.025	32%	0.324	C	S	.	.	H	α-helix	trans	-65	-28.1	176.8	0	0	0	0	0	113.2	R92 F95 I136 I137 I138 F142 I143	R92-A140 HydrophobicContact CB-CB 4.44Å; R92-A140 WeakPolarHBondContact CG-O 3.45Å; R92-A140 VanDerWaalsContact O-CB 3.3Å; R92-A140 WeakPolarHBondContact O-CB 3.5Å; F95-A140 HydrophobicContact CD1-CB 3.67Å; F95-A140 HydrophobicContact CE1-CB 4.35Å; I136-A140 PolarHBondContact O-N 3.45Å; I137-A140 WeakPolarHBondContact O-CA 3.44Å; I137-A140 VanDerWaalsContact O-CB 3.28Å; I137-A140 WeakPolarHBondContact O-CB 3.23Å; I137-A140 PolarHBondContact O-N 3.49Å; I138-A140 VanDerWaalsContact C-N 3.28Å; I138-A140 PolarHBondContact O-N 3.48Å; A140-F142 PolarHBondContact O-N 2.78Å; A140-I143 HydrophobicContact CB-CD1 4.34Å; A140-I143 WeakPolarHBondContact O-CB 3.37Å; A140-I143 WeakPolarHBondContact O-CG1 3.47Å; A140-I143 PolarHBondContact O-N 3.25Å
141	F	89.3	Confident	88.2	Confident	31 Å²	31	56.2 Å²	56.2	14%	0.136	34%	0.341	C	S	.	.	H	α-helix	trans	-67.7	-23.1	175.7	-83	-92.8	0	0	0	113.4	M56 I68 F71 A89 R92 L93 I137 I138 G139 I143	M56-F141 HydrophobicContact CE-CE2 4.47Å; M56-F141 HydrophobicContact CE-CZ 3.73Å; M56-F141 HydrophobicContact SD-CZ 4.24Å; I68-F141 HydrophobicContact CD1-CD1 4.26Å; I68-F141 HydrophobicContact CD1-CE1 4.41Å; F71-F141 AromaticContact CE2-CD1 3.76Å; F71-F141 HydrophobicContact CE2-CD1 3.76Å; F71-F141 HydrophobicContact CE2-CE1 4.32Å; F71-F141 AromaticContact CZ-CD1 3.61Å; F71-F141 HydrophobicContact CZ-CD1 3.61Å; F71-F141 AromaticContact CZ-CE1 3.75Å; F71-F141 HydrophobicContact CZ-CE1 3.75Å; A89-F141 HydrophobicContact CB-CE1 4.19Å; R92-F141 HydrophobicContact CB-CD2 4.49Å; R92-F141 HydrophobicContact CB-CE2 4.45Å; R92-F141 HydrophobicContact CB-CZ 4.46Å; L93-F141 HydrophobicContact CB-CE2 4.45Å; L93-F141 HydrophobicContact CB-CZ 4.46Å; I137-F141 HydrophobicContact CG2-CD2 4.25Å; I137-F141 HydrophobicContact CG2-CE2 3.91Å; I137-F141 VanDerWaalsContact O-CD2 3.28Å; I137-F141 WeakPolarHBondContact O-CD2 3.29Å; I137-F141 PolarHBondContact O-N 3.35Å; I138-F141 WeakPolarHBondContact O-CB 3.4Å; I138-F141 PolarHBondContact O-N 3.43Å; I138-F141 VanDerWaalsContact O-N 3.08Å; G139-F141 VanDerWaalsContact C-N 3.26Å; G139-F141 PolarHBondContact O-N 2.88Å; F141-I143 VanDerWaalsContact C-N 3.28Å; F141-I143 PolarHBondContact O-N 2.92Å
142	F	87.9	Confident	88.2	Confident	161 Å²	161	55.1 Å²	55.1	71%	0.706	33%	0.327	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.1	-2.1	175.9	-69.3	-83.8	0	0	0	114	I138 G139 A140 P144	I138-F142 HydrophobicContact CG2-CE2 3.96Å; I138-F142 VanDerWaalsContact O-CD2 3.25Å; I138-F142 WeakPolarHBondContact O-CD2 3.27Å; G139-F142 PolarHBondContact O-N 2.82Å; A140-F142 PolarHBondContact O-N 2.78Å; F142-P144 WeakPolarHBondContact O-CD 3.23Å
143	I	86.4	Confident	88	Confident	41 Å²	41	53 Å²	53	21%	0.21	31%	0.31	C	S	.	.	P	Polyproline II helix	trans	-72	119.9	179.1	-60.2	172.9	0	0	0	109.2	R92 F95 A140 F141 F148	R92-I143 PolarHBondContact NE-O 3.36Å; R92-I143 PolarHBondContact NH2-O 2.78Å; F95-I143 HydrophobicContact CD1-CD1 3.99Å; F95-I143 HydrophobicContact CE1-CD1 3.71Å; F95-I143 HydrophobicContact CZ-CD1 4.27Å; A140-I143 HydrophobicContact CB-CD1 4.34Å; A140-I143 WeakPolarHBondContact O-CB 3.37Å; A140-I143 WeakPolarHBondContact O-CG1 3.47Å; A140-I143 PolarHBondContact O-N 3.25Å; F141-I143 VanDerWaalsContact C-N 3.28Å; F141-I143 PolarHBondContact O-N 2.92Å; I143-F148 HydrophobicContact CD1-CD2 4.48Å; I143-F148 HydrophobicContact CD1-CE2 3.94Å; I143-F148 HydrophobicContact CD1-CZ 4.04Å; I143-F148 HydrophobicContact CG2-CB 4.03Å; I143-F148 HydrophobicContact CG2-CD1 3.94Å; I143-F148 HydrophobicContact CG2-CD2 3.86Å; I143-F148 HydrophobicContact CG2-CE1 4.39Å; I143-F148 HydrophobicContact CG2-CE2 4.31Å; I143-F148 HydrophobicContact CG2-CG 3.65Å
144	P	78.6	Confident	87.8	Confident	99 Å²	99	58 Å²	58	64%	0.643	33%	0.329	S	S	*	.	P	Polyproline II helix	trans	-68	156.9	-178.7	29	-35.1	0	0	0	111.5	F142	F142-P144 WeakPolarHBondContact O-CD 3.23Å
145	E	70.6	Confident	87.8	Confident	56 Å²	56	56.3 Å²	56.3	26%	0.262	32%	0.323	S	S	.	.	S	Bend	trans	-71.8	153.5	178.3	-62	-170.3	172.4	0	0	112.6	F71 K88 R92	F71-E145 WeakPolarHBondContact CA-OE1 3.35Å; K88-E145 WeakPolarHBondContact CD-OE1 3.37Å; K88-E145 WeakPolarHBondContact CE-OE1 3.09Å; K88-E145 IonicContact NZ-OE1 2.84Å; K88-E145 PolarHBondContact NZ-OE1 3.42Å; K88-E145 IonicContact NZ-OE2 2.71Å; K88-E145 PolarHBondContact NZ-OE2 3.17Å; R92-E145 VanDerWaalsContact NH2-CG 3.32Å
146	G	75.2	Confident	87.7	Confident	43 Å²	43	53.6 Å²	53.6	44%	0.443	30%	0.3	S	S	.	.	S	Bend	trans	141.1	-126.5	177.4	0	0	0	0	0	111.5	F148 T149	G146-F148 PolarHBondContact O-N 2.9Å; G146-T149 PolarHBondContact O-OG1 2.94Å
147	T	82.4	Confident	87.5	Confident	120 Å²	120	51.5 Å²	51.5	74%	0.736	29%	0.289	S	S	*	.	H	α-helix	trans	-62.3	-23.9	-176.8	52.4	0	0	0	0	113.4	T149 T150 V151	T147-T149 PolarHBondContact O-N 3Å; T147-T150 PolarHBondContact O-N 3.41Å; T147-V151 WeakPolarHBondContact O-CB 3.49Å; T147-V151 VanDerWaalsContact O-CG2 3.31Å; T147-V151 WeakPolarHBondContact O-CG2 3.47Å; T147-V151 PolarHBondContact O-N 3.46Å
148	F	86.2	Confident	87.5	Confident	34 Å²	34	53.1 Å²	53.1	15%	0.149	31%	0.306	C	S	.	.	H	α-helix	trans	-55.5	-51.9	-179.8	174.1	-104.4	0	0	0	112.7	R92 F95 I143 G146 T150 V151 W152	R92-F148 HydrophobicContact CG-CE1 4.38Å; F95-F148 HydrophobicContact CB-CZ 3.99Å; F95-F148 HydrophobicContact CD1-CZ 4.36Å; F95-F148 AromaticContact CD2-CE2 3.72Å; F95-F148 HydrophobicContact CD2-CE2 3.72Å; F95-F148 AromaticContact CD2-CZ 3.76Å; F95-F148 HydrophobicContact CD2-CZ 3.76Å; F95-F148 AromaticContact CE2-CE2 3.87Å; F95-F148 HydrophobicContact CE2-CE2 3.87Å; F95-F148 HydrophobicContact CE2-CZ 4.35Å; F95-F148 HydrophobicContact CG-CE2 4.13Å; F95-F148 AromaticContact CG-CZ 3.77Å; F95-F148 HydrophobicContact CG-CZ 3.77Å; F95-F148 HydrophobicContact CZ-CE2 4.38Å; I143-F148 HydrophobicContact CD1-CD2 4.48Å; I143-F148 HydrophobicContact CD1-CE2 3.94Å; I143-F148 HydrophobicContact CD1-CZ 4.04Å; I143-F148 HydrophobicContact CG2-CB 4.03Å; I143-F148 HydrophobicContact CG2-CD1 3.94Å; I143-F148 HydrophobicContact CG2-CD2 3.86Å; I143-F148 HydrophobicContact CG2-CE1 4.39Å; I143-F148 HydrophobicContact CG2-CE2 4.31Å; I143-F148 HydrophobicContact CG2-CG 3.65Å; G146-F148 PolarHBondContact O-N 2.9Å; F148-T150 VanDerWaalsContact C-N 3.3Å; F148-T150 PolarHBondContact O-N 2.89Å; F148-V151 PolarHBondContact O-N 3.17Å; F148-W152 HydrophobicContact CE2-CB 4.44Å; F148-W152 HydrophobicContact CE2-CG 4.49Å; F148-W152 HydrophobicContact CZ-CB 4.41Å; F148-W152 HydrophobicContact CZ-CG 4.26Å; F148-W152 WeakPolarHBondContact O-CB 3.29Å; F148-W152 PolarHBondContact O-N 3.36Å
149	T	82.3	Confident	87.6	Confident	12 Å²	12	48.8 Å²	48.8	7%	0.074	29%	0.285	C	S	.	.	H	α-helix	trans	-64.7	-37.2	-176.6	51.1	0	0	0	0	111.9	G146 T147 F153	G146-T149 PolarHBondContact O-OG1 2.94Å; T147-T149 PolarHBondContact O-N 3Å; T149-F153 VanDerWaalsContact O-CB 3.24Å; T149-F153 WeakPolarHBondContact O-CB 3.44Å; T149-F153 PolarHBondContact O-N 3.07Å
150	T	84.2	Confident	87.6	Confident	41 Å²	41	46.9 Å²	46.9	25%	0.252	27%	0.266	S	S	.	.	H	α-helix	trans	-69	-47.4	178.4	-56.2	0	0	0	0	111.5	T147 F148 F153 Y154	T147-T150 PolarHBondContact O-N 3.41Å; F148-T150 VanDerWaalsContact C-N 3.3Å; F148-T150 PolarHBondContact O-N 2.89Å; T150-F153 WeakPolarHBondContact O-CB 3.33Å; T150-F153 PolarHBondContact O-N 3.17Å; T150-Y154 HydrophobicContact CG2-CD2 4.41Å; T150-Y154 HydrophobicContact CG2-CE2 3.87Å; T150-Y154 WeakPolarHBondContact O-CD2 3.38Å; T150-Y154 PolarHBondContact O-N 3.34Å
151	V	89.7	Confident	87.7	Confident	87 Å²	87	49.4 Å²	49.4	53%	0.527	28%	0.276	S	S	.	.	H	α-helix	trans	-64.1	-45.9	177.6	173.2	0	0	0	0	110.1	T147 F148 F153 Y154 V155	T147-V151 WeakPolarHBondContact O-CB 3.49Å; T147-V151 VanDerWaalsContact O-CG2 3.31Å; T147-V151 WeakPolarHBondContact O-CG2 3.47Å; T147-V151 PolarHBondContact O-N 3.46Å; F148-V151 PolarHBondContact O-N 3.17Å; V151-F153 VanDerWaalsContact C-N 3.28Å; V151-F153 PolarHBondContact O-N 2.89Å; V151-Y154 PolarHBondContact O-N 3.21Å; V151-Y154 VanDerWaalsContact O-N 3.13Å; V151-V155 WeakPolarHBondContact O-CG2 3.02Å; V151-V155 PolarHBondContact O-N 2.98Å
152	W	91.8	Very high	87.9	Confident	22 Å²	22	50.5 Å²	50.5	8%	0.083	29%	0.287	C	S	.	.	H	α-helix	trans	-67.1	-28.7	-179.3	-160.8	-116.9	0	0	0	112.7	Y91 F95 A98 F148 V155 G156 L398 M401	Y91-W152 HydrophobicContact CD1-CB 4.35Å; Y91-W152 AromaticContact CD1-CD1 3.66Å; Y91-W152 HydrophobicContact CD1-CG 4.4Å; F95-W152 HydrophobicContact CB-CZ2 4.05Å; F95-W152 AromaticContact CD2-CD2 3.75Å; F95-W152 HydrophobicContact CD2-CD2 3.75Å; F95-W152 AromaticContact CD2-CE2 3.58Å; F95-W152 AromaticContact CD2-CE3 3.77Å; F95-W152 HydrophobicContact CD2-CE3 3.77Å; F95-W152 AromaticContact CD2-CH2 3.54Å; F95-W152 HydrophobicContact CD2-CH2 3.54Å; F95-W152 AromaticContact CD2-CZ2 3.51Å; F95-W152 HydrophobicContact CD2-CZ2 3.51Å; F95-W152 AromaticContact CD2-CZ3 3.67Å; F95-W152 HydrophobicContact CD2-CZ3 3.67Å; F95-W152 HydrophobicContact CE2-CE3 4.12Å; F95-W152 AromaticContact CE2-CH2 4Å; F95-W152 HydrophobicContact CE2-CH2 4Å; F95-W152 HydrophobicContact CE2-CZ2 4.4Å; F95-W152 AromaticContact CE2-CZ3 3.83Å; F95-W152 HydrophobicContact CE2-CZ3 3.83Å; F95-W152 HydrophobicContact CG-CZ2 4.2Å; A98-W152 HydrophobicContact CB-CH2 4.27Å; A98-W152 HydrophobicContact CB-CZ2 3.92Å; F148-W152 HydrophobicContact CE2-CB 4.44Å; F148-W152 HydrophobicContact CE2-CG 4.49Å; F148-W152 HydrophobicContact CZ-CB 4.41Å; F148-W152 HydrophobicContact CZ-CG 4.26Å; F148-W152 WeakPolarHBondContact O-CB 3.29Å; F148-W152 PolarHBondContact O-N 3.36Å; W152-V155 HydrophobicContact CE3-CB 4.02Å; W152-V155 HydrophobicContact CE3-CG1 4.01Å; W152-V155 HydrophobicContact CE3-CG2 4.35Å; W152-V155 HydrophobicContact CH2-CG1 4.2Å; W152-V155 HydrophobicContact CZ3-CB 4.26Å; W152-V155 HydrophobicContact CZ3-CG1 3.74Å; W152-V155 PolarHBondContact O-N 2.95Å; W152-G156 WeakPolarHBondContact O-CA 3.25Å; W152-G156 PolarHBondContact O-N 3.37Å; W152-L398 HydrophobicContact CH2-CD2 3.94Å; W152-L398 HydrophobicContact CZ2-CD2 3.37Å; W152-M401 HydrophobicContact CG-CE 4.46Å; W152-M401 HydrophobicContact CG-SD 4.44Å; W152-M401 PolarHBondContact NE1-SD 3.22Å
153	F	89.7	Confident	88.1	Confident	2 Å²	2	43.2 Å²	43.2	1%	0.009	26%	0.255	C	S	.	.	H	α-helix	trans	-60.7	-46.5	169.3	171.8	-95.9	0	0	0	111.7	Y91 T149 T150 V151 G156 M157 M402 Y408 R409	Y91-F153 HydrophobicContact CE1-CB 4.27Å; Y91-F153 WeakPolarHBondContact OH-CD2 3.35Å; T149-F153 VanDerWaalsContact O-CB 3.24Å; T149-F153 WeakPolarHBondContact O-CB 3.44Å; T149-F153 PolarHBondContact O-N 3.07Å; T150-F153 WeakPolarHBondContact O-CB 3.33Å; T150-F153 PolarHBondContact O-N 3.17Å; V151-F153 VanDerWaalsContact C-N 3.28Å; V151-F153 PolarHBondContact O-N 2.89Å; F153-G156 PolarHBondContact O-N 3.45Å; F153-M157 HydrophobicContact CD1-CE 3.51Å; F153-M157 HydrophobicContact CD1-SD 4.12Å; F153-M157 HydrophobicContact CE1-CE 3.17Å; F153-M157 HydrophobicContact CE1-CG 4.24Å; F153-M157 HydrophobicContact CE1-SD 3.39Å; F153-M157 WeakPolarHBondContact CE1-SD 3.39Å; F153-M157 HydrophobicContact CE2-CG 4.4Å; F153-M157 HydrophobicContact CE2-SD 4.25Å; F153-M157 HydrophobicContact CG-CE 4.49Å; F153-M157 HydrophobicContact CZ-CE 3.92Å; F153-M157 HydrophobicContact CZ-CG 4.15Å; F153-M157 HydrophobicContact CZ-SD 3.44Å; F153-M157 WeakPolarHBondContact CZ-SD 3.29Å; F153-M157 WeakPolarHBondContact O-CG 3.38Å; F153-M157 PolarHBondContact O-N 2.99Å; F153-M402 HydrophobicContact CD2-CE 3.68Å; F153-M402 HydrophobicContact CD2-SD 4.38Å; F153-M402 HydrophobicContact CE2-CE 3.59Å; F153-M402 HydrophobicContact CZ-CE 4.44Å; F153-Y408 WeakPolarHBondContact CE2-O 3.43Å; F153-R409 HydrophobicContact CD1-CG 4.21Å; F153-R409 HydrophobicContact CE1-CB 3.98Å; F153-R409 HydrophobicContact CE1-CG 4.03Å; F153-R409 HydrophobicContact CE2-CB 4.06Å; F153-R409 HydrophobicContact CZ-CB 3.75Å; F153-R409 HydrophobicContact CZ-CG 4.3Å
154	Y	91.4	Very high	88.4	Confident	106 Å²	106	41.4 Å²	41.4	42%	0.416	25%	0.246	S	C	.	.	H	α-helix	trans	-65.9	-41.3	177	-69.4	-71.4	0	0	0	112.8	T150 V151 G156 M157 A158 R409	T150-Y154 HydrophobicContact CG2-CD2 4.41Å; T150-Y154 HydrophobicContact CG2-CE2 3.87Å; T150-Y154 WeakPolarHBondContact O-CD2 3.38Å; T150-Y154 PolarHBondContact O-N 3.34Å; V151-Y154 PolarHBondContact O-N 3.21Å; V151-Y154 VanDerWaalsContact O-N 3.13Å; Y154-G156 VanDerWaalsContact C-N 3.33Å; Y154-M157 HydrophobicContact CD1-CE 3.21Å; Y154-M157 HydrophobicContact CE1-CE 3.65Å; Y154-M157 HydrophobicContact CG-CE 4.03Å; Y154-M157 PolarHBondContact O-N 3.46Å; Y154-A158 PolarHBondContact O-N 2.73Å; Y154-R409 PolarHBondContact OH-NH2 3.35Å; Y154-R409 VanDerWaalsContact OH-NH2 3.15Å
155	V	93.9	Very high	89.1	Confident	56 Å²	56	38.5 Å²	38.5	34%	0.339	23%	0.225	S	C	.	.	H	α-helix	trans	-61.8	-44.5	174	176	0	0	0	0	110.6	V151 W152 A158 G159 L398	V151-V155 WeakPolarHBondContact O-CG2 3.02Å; V151-V155 PolarHBondContact O-N 2.98Å; W152-V155 HydrophobicContact CE3-CB 4.02Å; W152-V155 HydrophobicContact CE3-CG1 4.01Å; W152-V155 HydrophobicContact CE3-CG2 4.35Å; W152-V155 HydrophobicContact CH2-CG1 4.2Å; W152-V155 HydrophobicContact CZ3-CB 4.26Å; W152-V155 HydrophobicContact CZ3-CG1 3.74Å; W152-V155 PolarHBondContact O-N 2.95Å; V155-A158 PolarHBondContact O-N 3.22Å; V155-G159 PolarHBondContact O-N 2.81Å; V155-L398 HydrophobicContact CG1-CD1 4.26Å
156	G	94.2	Very high	90	Very high	0 Å²	0	37.4 Å²	37.4	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-58.8	-46	175.8	0	0	0	0	0	112.6	W152 F153 Y154 G159 A160 M402	W152-G156 WeakPolarHBondContact O-CA 3.25Å; W152-G156 PolarHBondContact O-N 3.37Å; F153-G156 PolarHBondContact O-N 3.45Å; Y154-G156 VanDerWaalsContact C-N 3.33Å; G156-G159 PolarHBondContact O-N 3.41Å; G156-A160 WeakPolarHBondContact O-CB 3.37Å; G156-A160 PolarHBondContact O-N 3.36Å; G156-M402 VanDerWaalsContact C-CG 3.45Å; G156-M402 WeakPolarHBondContact O-CG 3.38Å
157	M	91.6	Very high	90.8	Very high	9 Å²	9	35.8 Å²	35.8	4%	0.044	20%	0.201	C	C	.	.	H	α-helix	trans	-61.3	-46.8	176.5	-76.1	-168.5	-61	0	0	112.4	F153 Y154 A160 F161 M402 W407 T421	F153-M157 HydrophobicContact CD1-CE 3.51Å; F153-M157 HydrophobicContact CD1-SD 4.12Å; F153-M157 HydrophobicContact CE1-CE 3.17Å; F153-M157 HydrophobicContact CE1-CG 4.24Å; F153-M157 HydrophobicContact CE1-SD 3.39Å; F153-M157 WeakPolarHBondContact CE1-SD 3.39Å; F153-M157 HydrophobicContact CE2-CG 4.4Å; F153-M157 HydrophobicContact CE2-SD 4.25Å; F153-M157 HydrophobicContact CG-CE 4.49Å; F153-M157 HydrophobicContact CZ-CE 3.92Å; F153-M157 HydrophobicContact CZ-CG 4.15Å; F153-M157 HydrophobicContact CZ-SD 3.44Å; F153-M157 WeakPolarHBondContact CZ-SD 3.29Å; F153-M157 WeakPolarHBondContact O-CG 3.38Å; F153-M157 PolarHBondContact O-N 2.99Å; Y154-M157 HydrophobicContact CD1-CE 3.21Å; Y154-M157 HydrophobicContact CE1-CE 3.65Å; Y154-M157 HydrophobicContact CG-CE 4.03Å; Y154-M157 PolarHBondContact O-N 3.46Å; M157-A160 PolarHBondContact O-N 3.36Å; M157-F161 WeakPolarHBondContact O-CB 3.33Å; M157-F161 PolarHBondContact O-N 2.89Å; M157-M402 HydrophobicContact CG-CE 3.5Å; M157-M402 HydrophobicContact CG-SD 4.4Å; M157-W407 HydrophobicContact CB-CZ3 4.41Å; M157-W407 HydrophobicContact CG-CE3 4.19Å; M157-W407 HydrophobicContact CG-CZ3 4.08Å; M157-T421 HydrophobicContact CE-CG2 4Å; M157-T421 HydrophobicContact SD-CG2 3.63Å
158	A	93.8	Very high	91.2	Very high	57 Å²	57	30.1 Å²	30.1	47%	0.471	17%	0.166	S	C	.	.	H	α-helix	trans	-63	-45.1	178.2	0	0	0	0	0	111.2	Y154 V155 F161 C162	Y154-A158 PolarHBondContact O-N 2.73Å; V155-A158 PolarHBondContact O-N 3.22Å; A158-F161 PolarHBondContact O-N 3.47Å; A158-C162 PolarHBondContact O-N 2.93Å; A158-C162 VanDerWaalsContact O-N 3.09Å; A158-C162 PolarHBondContact O-SG 3.48Å; A158-C162 VanDerWaalsContact O-SG 3.37Å
159	G	94.8	Very high	91.4	Very high	5 Å²	5	30.6 Å²	30.6	5%	0.052	17%	0.172	C	C	.	.	H	α-helix	trans	-64.3	-41.1	177	0	0	0	0	0	113.2	V155 G156 C162 F163	V155-G159 PolarHBondContact O-N 2.81Å; G156-G159 PolarHBondContact O-N 3.41Å; G159-C162 PolarHBondContact O-N 2.97Å; G159-F163 WeakPolarHBondContact O-CB 3.2Å; G159-F163 PolarHBondContact O-N 3.05Å
160	A	93.6	Very high	91.8	Very high	0 Å²	0	30.7 Å²	30.7	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-64.7	-40.5	176.3	0	0	0	0	0	111.9	G156 M157 F163 I164 Y399 M402 W407	G156-A160 WeakPolarHBondContact O-CB 3.37Å; G156-A160 PolarHBondContact O-N 3.36Å; M157-A160 PolarHBondContact O-N 3.36Å; A160-F163 PolarHBondContact O-N 3.35Å; A160-I164 VanDerWaalsContact O-CG1 3.22Å; A160-I164 WeakPolarHBondContact O-CG1 3.49Å; A160-I164 PolarHBondContact O-N 3.48Å; A160-Y399 HydrophobicContact CB-CD2 4.16Å; A160-M402 HydrophobicContact CB-CB 4.19Å; A160-M402 HydrophobicContact CB-CG 3.96Å; A160-W407 HydrophobicContact CB-CH2 3.39Å; A160-W407 HydrophobicContact CB-CZ2 3.78Å; A160-W407 HydrophobicContact CB-CZ3 4.26Å
161	F	93.3	Very high	92.1	Very high	56 Å²	56	30.2 Å²	30.2	25%	0.246	17%	0.167	C	C	.	.	H	α-helix	trans	-57.6	-51.1	172.1	174.1	-107.1	0	0	0	111.2	M157 A158 F163 I164 L165 V425 S429 I432	M157-F161 WeakPolarHBondContact O-CB 3.33Å; M157-F161 PolarHBondContact O-N 2.89Å; A158-F161 PolarHBondContact O-N 3.47Å; F161-F163 VanDerWaalsContact C-N 3.3Å; F161-F163 PolarHBondContact O-N 3.43Å; F161-I164 PolarHBondContact O-N 2.9Å; F161-L165 HydrophobicContact CD1-CD1 4.39Å; F161-L165 HydrophobicContact CE1-CD1 3.79Å; F161-L165 HydrophobicContact CZ-CD1 3.87Å; F161-L165 HydrophobicContact CZ-CG 4.36Å; F161-L165 PolarHBondContact O-N 3.04Å; F161-L165 VanDerWaalsContact O-N 3.11Å; F161-V425 HydrophobicContact CB-CG1 3.87Å; F161-V425 HydrophobicContact CD2-CG1 4.01Å; F161-V425 HydrophobicContact CG-CG1 4.42Å; F161-S429 VanDerWaalsContact CD2-OG 3.25Å; F161-S429 WeakPolarHBondContact CD2-OG 3.07Å; F161-S429 WeakPolarHBondContact CE2-OG 3.46Å; F161-I432 HydrophobicContact CE2-CD1 4.25Å; F161-I432 HydrophobicContact CZ-CD1 3.83Å
162	C	93.5	Very high	92.2	Very high	54 Å²	54	26.5 Å²	26.5	37%	0.365	14%	0.144	S	C	.	.	H	α-helix	trans	-59.4	-40.9	176.9	-65.4	0	0	0	0	112.3	A158 G159 L165 I166 L395	A158-C162 PolarHBondContact O-N 2.93Å; A158-C162 VanDerWaalsContact O-N 3.09Å; A158-C162 PolarHBondContact O-SG 3.48Å; A158-C162 VanDerWaalsContact O-SG 3.37Å; G159-C162 PolarHBondContact O-N 2.97Å; C162-L165 PolarHBondContact O-N 2.67Å; C162-I166 WeakPolarHBondContact O-CG1 2.92Å; C162-I166 PolarHBondContact O-N 2.91Å; C162-I166 VanDerWaalsContact O-N 3.07Å; C162-L395 HydrophobicContact CB-CD1 3.88Å; C162-L395 HydrophobicContact CB-CD2 4.13Å
163	F	93.9	Very high	92	Very high	7 Å²	7	26.7 Å²	26.7	3%	0.031	15%	0.147	C	C	.	.	H	α-helix	trans	-66	-39.5	177	-170.6	-97.6	0	0	0	112.6	G159 A160 F161 L165 I166 Q167 F324 V328 L395 A396 Y399	G159-F163 WeakPolarHBondContact O-CB 3.2Å; G159-F163 PolarHBondContact O-N 3.05Å; A160-F163 PolarHBondContact O-N 3.35Å; F161-F163 VanDerWaalsContact C-N 3.3Å; F161-F163 PolarHBondContact O-N 3.43Å; F163-L165 VanDerWaalsContact C-N 3.26Å; F163-L165 PolarHBondContact O-N 3.41Å; F163-I166 PolarHBondContact O-N 3.28Å; F163-Q167 HydrophobicContact CE1-CB 4.46Å; F163-Q167 VanDerWaalsContact O-CB 3.32Å; F163-Q167 WeakPolarHBondContact O-CB 2.92Å; F163-Q167 PolarHBondContact O-N 2.85Å; F163-F324 AromaticContact CE1-CD2 3.62Å; F163-F324 HydrophobicContact CE1-CD2 3.62Å; F163-F324 HydrophobicContact CE1-CE2 4.12Å; F163-F324 AromaticContact CZ-CD2 3.76Å; F163-F324 HydrophobicContact CZ-CD2 3.76Å; F163-F324 AromaticContact CZ-CE2 3.91Å; F163-F324 HydrophobicContact CZ-CE2 3.91Å; F163-V328 HydrophobicContact CZ-CG2 4.37Å; F163-L395 HydrophobicContact CB-CB 4.1Å; F163-L395 HydrophobicContact CD2-CB 4.13Å; F163-A396 VanDerWaalsContact CD2-CA 3.47Å; F163-A396 HydrophobicContact CD2-CB 3.85Å; F163-A396 HydrophobicContact CE2-CB 3.38Å; F163-A396 HydrophobicContact CZ-CB 3.92Å; F163-Y399 HydrophobicContact CB-CG 4.4Å; F163-Y399 AromaticContact CD1-CD1 3.83Å; F163-Y399 HydrophobicContact CD1-CD1 3.83Å; F163-Y399 AromaticContact CD1-CD2 3.82Å; F163-Y399 HydrophobicContact CD1-CD2 3.82Å; F163-Y399 HydrophobicContact CD1-CE2 4.48Å; F163-Y399 AromaticContact CD1-CG 3.43Å; F163-Y399 HydrophobicContact CD1-CG 3.43Å; F163-Y399 VanDerWaalsContact CD1-CG 3.43Å; F163-Y399 AromaticContact CE1-CD1 3.96Å; F163-Y399 HydrophobicContact CE1-CD1 3.96Å; F163-Y399 HydrophobicContact CE1-CE1 4.48Å; F163-Y399 HydrophobicContact CE1-CG 4.06Å; F163-Y399 HydrophobicContact CG-CG 4.19Å
164	I	92.3	Very high	92	Very high	3 Å²	3	30.2 Å²	30.2	2%	0.015	16%	0.163	C	C	.	.	H	α-helix	trans	-60.7	-38.6	175.3	-68.7	163.4	0	0	0	110.4	A160 F161 Q167 L168 L274 Y399 W407 V425	A160-I164 VanDerWaalsContact O-CG1 3.22Å; A160-I164 WeakPolarHBondContact O-CG1 3.49Å; A160-I164 PolarHBondContact O-N 3.48Å; F161-I164 PolarHBondContact O-N 2.9Å; I164-Q167 PolarHBondContact O-N 3.31Å; I164-L168 HydrophobicContact CG2-CD1 4.15Å; I164-L168 WeakPolarHBondContact O-CB 3.49Å; I164-L168 WeakPolarHBondContact O-CG 3.37Å; I164-L168 PolarHBondContact O-N 3.36Å; I164-L274 HydrophobicContact CG2-CD1 4.48Å; I164-L274 HydrophobicContact CG2-CD2 4.4Å; I164-Y399 HydrophobicContact CD1-CD2 4.37Å; I164-Y399 HydrophobicContact CD1-CE2 4.05Å; I164-Y399 HydrophobicContact CG1-CD2 3.88Å; I164-Y399 HydrophobicContact CG1-CE2 3.59Å; I164-W407 HydrophobicContact CD1-CH2 4.28Å; I164-W407 HydrophobicContact CD1-CZ2 4.2Å; I164-V425 HydrophobicContact CD1-CG1 4.44Å
165	L	91.9	Very high	92.1	Very high	39 Å²	39	25.2 Å²	25.2	20%	0.204	14%	0.143	C	C	.	.	H	α-helix	trans	-64.6	-43.1	174.5	-63.5	-176.8	0	0	0	112.3	F161 C162 F163 Q167 L168 V169 I432	F161-L165 HydrophobicContact CD1-CD1 4.39Å; F161-L165 HydrophobicContact CE1-CD1 3.79Å; F161-L165 HydrophobicContact CZ-CD1 3.87Å; F161-L165 HydrophobicContact CZ-CG 4.36Å; F161-L165 PolarHBondContact O-N 3.04Å; F161-L165 VanDerWaalsContact O-N 3.11Å; C162-L165 PolarHBondContact O-N 2.67Å; F163-L165 VanDerWaalsContact C-N 3.26Å; F163-L165 PolarHBondContact O-N 3.41Å; L165-Q167 VanDerWaalsContact C-N 3.34Å; L165-L168 HydrophobicContact CD2-CD1 4.23Å; L165-L168 WeakPolarHBondContact O-CB 3.22Å; L165-L168 PolarHBondContact O-N 3.48Å; L165-V169 WeakPolarHBondContact O-CG2 3.34Å; L165-V169 PolarHBondContact O-N 3.46Å; L165-I432 HydrophobicContact CD2-CB 3.99Å; L165-I432 HydrophobicContact CD2-CD1 4.18Å; L165-I432 HydrophobicContact CD2-CG2 3.64Å
166	I	90.5	Very high	91.8	Very high	33 Å²	33	23.7 Å²	23.7	17%	0.169	13%	0.133	C	C	.	.	H	α-helix	trans	-62.5	-44.2	174.7	-67.3	164	0	0	0	110.4	C162 F163 L168 V169 L170 M392 L395	C162-I166 WeakPolarHBondContact O-CG1 2.92Å; C162-I166 PolarHBondContact O-N 2.91Å; C162-I166 VanDerWaalsContact O-N 3.07Å; F163-I166 PolarHBondContact O-N 3.28Å; I166-L168 VanDerWaalsContact C-N 3.29Å; I166-L168 PolarHBondContact O-N 2.94Å; I166-V169 PolarHBondContact O-N 3.3Å; I166-L170 HydrophobicContact CG2-CD1 3.91Å; I166-L170 HydrophobicContact CG2-CG 4.4Å; I166-L170 WeakPolarHBondContact O-CG 3.44Å; I166-L170 PolarHBondContact O-N 3.23Å; I166-M392 HydrophobicContact CD1-CG 4.21Å; I166-M392 HydrophobicContact CG2-SD 4.01Å; I166-L395 HydrophobicContact CD1-CD1 3.57Å
167	Q	92.1	Very high	91.6	Very high	8 Å²	8	24.9 Å²	24.9	4%	0.037	14%	0.141	C	C	.	.	H	α-helix	trans	-60.4	-38.4	176.5	-177.8	175.6	28.3	0	0	111.7	F163 I164 L165 L170 L171 Y270 L323 C327	F163-Q167 HydrophobicContact CE1-CB 4.46Å; F163-Q167 VanDerWaalsContact O-CB 3.32Å; F163-Q167 WeakPolarHBondContact O-CB 2.92Å; F163-Q167 PolarHBondContact O-N 2.85Å; I164-Q167 PolarHBondContact O-N 3.31Å; L165-Q167 VanDerWaalsContact C-N 3.34Å; Q167-L170 PolarHBondContact O-N 3.38Å; Q167-L171 VanDerWaalsContact O-CB 3.27Å; Q167-L171 WeakPolarHBondContact O-CB 3.27Å; Q167-L171 PolarHBondContact O-N 3.37Å; Q167-Y270 PolarHBondContact OE1-OH 2.96Å; Q167-L323 VanDerWaalsContact NE2-C 3.33Å; Q167-L323 PolarHBondContact NE2-O 2.67Å; Q167-C327 HydrophobicContact CG-CB 4.16Å
168	L	91.4	Very high	91.5	Very high	2 Å²	2	28 Å²	28	1%	0.01	15%	0.152	C	C	.	.	H	α-helix	trans	-63.2	-46.5	173.7	-85.1	161.8	0	0	0	112.1	I164 L165 I166 L171 I172 Y270 S429	I164-L168 HydrophobicContact CG2-CD1 4.15Å; I164-L168 WeakPolarHBondContact O-CB 3.49Å; I164-L168 WeakPolarHBondContact O-CG 3.37Å; I164-L168 PolarHBondContact O-N 3.36Å; L165-L168 HydrophobicContact CD2-CD1 4.23Å; L165-L168 WeakPolarHBondContact O-CB 3.22Å; L165-L168 PolarHBondContact O-N 3.48Å; I166-L168 VanDerWaalsContact C-N 3.29Å; I166-L168 PolarHBondContact O-N 2.94Å; L168-L171 PolarHBondContact O-N 3.25Å; L168-I172 VanDerWaalsContact O-CG1 3.32Å; L168-I172 WeakPolarHBondContact O-CG1 3.47Å; L168-I172 PolarHBondContact O-N 3.44Å; L168-Y270 HydrophobicContact CD2-CD1 3.57Å; L168-Y270 HydrophobicContact CD2-CE1 3.27Å; L168-Y270 HydrophobicContact CG-CE1 3.76Å; L168-S429 WeakPolarHBondContact CD1-O 3.4Å
169	V	90	Very high	91.4	Very high	43 Å²	43	25.4 Å²	25.4	26%	0.261	13%	0.13	S	C	.	.	H	α-helix	trans	-61.5	-45.3	176.9	173.5	0	0	0	0	110.8	L165 I166 L171 I172 D173 L436	L165-V169 WeakPolarHBondContact O-CG2 3.34Å; L165-V169 PolarHBondContact O-N 3.46Å; I166-V169 PolarHBondContact O-N 3.3Å; V169-L171 VanDerWaalsContact C-N 3.31Å; V169-L171 PolarHBondContact O-N 3.35Å; V169-I172 PolarHBondContact O-N 2Å; V169-D173 WeakPolarHBondContact O-CB 3.47Å; V169-D173 PolarHBondContact O-N 3.25Å; V169-L436 HydrophobicContact CG2-CD1 4.1Å
170	L	89.9	Confident	91.1	Very high	15 Å²	15	28.1 Å²	28.1	8%	0.079	14%	0.141	C	C	.	.	H	α-helix	trans	-64.2	-35.5	177	-70.5	171.9	0	0	0	112.4	I166 Q167 F174 C327 Y330	I166-L170 HydrophobicContact CG2-CD1 3.91Å; I166-L170 HydrophobicContact CG2-CG 4.4Å; I166-L170 WeakPolarHBondContact O-CG 3.44Å; I166-L170 PolarHBondContact O-N 3.23Å; Q167-L170 PolarHBondContact O-N 3.38Å; L170-F174 VanDerWaalsContact O-CB 3.3Å; L170-F174 WeakPolarHBondContact O-CB 3.25Å; L170-F174 PolarHBondContact O-N 2.99Å; L170-C327 WeakPolarHBondContact CD1-SG 3.34Å; L170-Y330 HydrophobicContact CB-CD1 4.34Å; L170-Y330 HydrophobicContact CD2-CD1 4.25Å; L170-Y330 HydrophobicContact CD2-CE1 4.34Å
171	L	91.4	Very high	90.9	Very high	30 Å²	30	30 Å²	30	16%	0.157	16%	0.155	C	C	.	.	H	α-helix	trans	-68.2	-42.5	175.2	-176	76.9	0	0	0	112	Q167 L168 V169 F174 A175 V266 I267 Y270	Q167-L171 VanDerWaalsContact O-CB 3.27Å; Q167-L171 WeakPolarHBondContact O-CB 3.27Å; Q167-L171 PolarHBondContact O-N 3.37Å; L168-L171 PolarHBondContact O-N 3.25Å; V169-L171 VanDerWaalsContact C-N 3.31Å; V169-L171 PolarHBondContact O-N 3.35Å; L171-F174 WeakPolarHBondContact O-CB 3.34Å; L171-F174 PolarHBondContact O-N 3.29Å; L171-A175 WeakPolarHBondContact O-CB 3.38Å; L171-A175 PolarHBondContact O-N 3.31Å; L171-V266 HydrophobicContact CD1-CG1 4.23Å; L171-V266 HydrophobicContact CG-CG1 4.39Å; L171-I267 HydrophobicContact CD2-CD1 4.13Å; L171-I267 HydrophobicContact CG-CD1 4.4Å; L171-Y270 VanDerWaalsContact CD2-CB 3.45Å; L171-Y270 HydrophobicContact CD2-CD1 3.64Å; L171-Y270 HydrophobicContact CD2-CD2 3.62Å; L171-Y270 HydrophobicContact CD2-CE1 4.25Å; L171-Y270 HydrophobicContact CD2-CE2 4.22Å; L171-Y270 HydrophobicContact CD2-CG 3.27Å
172	I	90.8	Very high	90.8	Very high	9 Å²	9	29.9 Å²	29.9	5%	0.046	15%	0.153	C	C	.	.	H	α-helix	trans	-60.1	-50.1	175.9	-71	163.7	0	0	0	109.5	L168 V169 F174 A175 H176 I267 L436 Y437 T440	L168-I172 VanDerWaalsContact O-CG1 3.32Å; L168-I172 WeakPolarHBondContact O-CG1 3.47Å; L168-I172 PolarHBondContact O-N 3.44Å; V169-I172 PolarHBondContact O-N 2Å; I172-F174 VanDerWaalsContact C-N 3.33Å; I172-F174 PolarHBondContact O-N 2.93Å; I172-A175 WeakPolarHBondContact O-CB 3.46Å; I172-A175 PolarHBondContact O-N 2.85Å; I172-A175 VanDerWaalsContact O-N 3.12Å; I172-H176 PolarHBondContact O-CD2 3.37Å; I172-H176 PolarHBondContact O-N 2.84Å; I172-I267 HydrophobicContact CB-CD1 4.44Å; I172-I267 HydrophobicContact CG1-CD1 3.53Å; I172-I267 HydrophobicContact CG1-CG1 4.38Å; I172-L436 HydrophobicContact CD1-CB 4.07Å; I172-Y437 HydrophobicContact CG1-CD2 4.48Å; I172-Y437 HydrophobicContact CG2-CD2 4.33Å; I172-T440 HydrophobicContact CG2-CG2 4.1Å
173	D	88.2	Confident	90.6	Very high	26 Å²	26	28.2 Å²	28.2	14%	0.139	14%	0.141	C	C	.	.	H	α-helix	trans	-59.9	-40.7	177.3	169.6	81.5	0	0	0	112.4	V169 H176 S177 Y330 R334	V169-D173 WeakPolarHBondContact O-CB 3.47Å; V169-D173 PolarHBondContact O-N 3.25Å; D173-H176 PolarHBondContact O-N 2.96Å; D173-S177 PolarHBondContact O-N 3.25Å; D173-Y330 WeakPolarHBondContact OD2-CE1 3.44Å; D173-Y330 PolarHBondContact OD2-OH 3.04Å; D173-R334 VanDerWaalsContact CG-CZ 3.42Å; D173-R334 VanDerWaalsContact CG-NH2 3.3Å; D173-R334 IonicContact OD1-CZ 2.8Å; D173-R334 IonicContact OD1-NE 3.69Å; D173-R334 PolarHBondContact OD1-NE 2.94Å; D173-R334 IonicContact OD1-NH2 3.21Å; D173-R334 PolarHBondContact OD1-NH2 3.28Å; D173-R334 WeakPolarHBondContact OD2-CD 3.15Å; D173-R334 IonicContact OD2-CZ 3.83Å; D173-R334 IonicContact OD2-NE 2.82Å; D173-R334 PolarHBondContact OD2-NE 3.29Å; D173-R334 IonicContact OD2-NH1 2.86Å; D173-R334 IonicContact OD2-NH2 2.68Å; D173-R334 PolarHBondContact OD2-NH2 2.89Å
174	F	90.4	Very high	90.4	Very high	77 Å²	77	31.7 Å²	31.7	34%	0.338	16%	0.157	S	C	.	.	H	α-helix	trans	-60.5	-46.3	171.3	170	-103.3	0	0	0	112.4	L170 L171 I172 S177 W178 Y330	L170-F174 VanDerWaalsContact O-CB 3.3Å; L170-F174 WeakPolarHBondContact O-CB 3.25Å; L170-F174 PolarHBondContact O-N 2.99Å; L171-F174 WeakPolarHBondContact O-CB 3.34Å; L171-F174 PolarHBondContact O-N 3.29Å; I172-F174 VanDerWaalsContact C-N 3.33Å; I172-F174 PolarHBondContact O-N 2.93Å; F174-S177 PolarHBondContact O-N 3.36Å; F174-W178 HydrophobicContact CD1-CE3 4.46Å; F174-W178 AromaticContact CE1-CE3 3.44Å; F174-W178 HydrophobicContact CE1-CE3 3.44Å; F174-W178 VanDerWaalsContact CE1-CE3 3.44Å; F174-W178 AromaticContact CE1-CZ3 3.85Å; F174-W178 HydrophobicContact CE1-CZ3 3.85Å; F174-W178 HydrophobicContact CE2-CE3 4.49Å; F174-W178 HydrophobicContact CZ-CD2 4.29Å; F174-W178 AromaticContact CZ-CE3 3.45Å; F174-W178 HydrophobicContact CZ-CE3 3.45Å; F174-W178 VanDerWaalsContact CZ-CE3 3.45Å; F174-W178 AromaticContact CZ-CZ3 3.91Å; F174-W178 HydrophobicContact CZ-CZ3 3.91Å; F174-W178 WeakPolarHBondContact O-CB 3.41Å; F174-W178 PolarHBondContact O-N 3.3Å; F174-Y330 WeakPolarHBondContact CA-OH 3.37Å; F174-Y330 HydrophobicContact CB-CE1 4.07Å; F174-Y330 HydrophobicContact CB-CE2 4.06Å; F174-Y330 HydrophobicContact CD2-CD2 4.13Å; F174-Y330 AromaticContact CD2-CE2 3.71Å; F174-Y330 HydrophobicContact CD2-CE2 3.71Å; F174-Y330 HydrophobicContact CG-CE2 4.37Å; F174-Y330 PolarHBondContact N-OH 2.99Å
175	A	92.1	Very high	90.3	Very high	1 Å²	1	35.5 Å²	35.5	1%	0.008	17%	0.173	C	C	.	.	H	α-helix	trans	-63.9	-42.9	-179.3	0	0	0	0	0	111.5	L171 I172 N179 Q263 V266	L171-A175 WeakPolarHBondContact O-CB 3.38Å; L171-A175 PolarHBondContact O-N 3.31Å; I172-A175 WeakPolarHBondContact O-CB 3.46Å; I172-A175 PolarHBondContact O-N 2.85Å; I172-A175 VanDerWaalsContact O-N 3.12Å; A175-N179 PolarHBondContact O-N 2.96Å; A175-Q263 HydrophobicContact CB-CB 4.33Å; A175-Q263 HydrophobicContact CB-CG 4.39Å; A175-V266 HydrophobicContact CB-CB 4.16Å; A175-V266 HydrophobicContact CB-CG1 4.11Å
176	H	89	Confident	90.1	Very high	24 Å²	24	35.7 Å²	35.7	11%	0.111	17%	0.174	C	C	.	.	H	α-helix	trans	-58.6	-54.8	173.9	-80.4	-76.8	0	0	0	110.9	I172 D173 W178 N179 E180 T440	I172-H176 PolarHBondContact O-CD2 3.37Å; I172-H176 PolarHBondContact O-N 2.84Å; D173-H176 PolarHBondContact O-N 2.96Å; H176-W178 VanDerWaalsContact C-N 3.34Å; H176-W178 PolarHBondContact O-N 2.92Å; H176-N179 WeakPolarHBondContact O-CA 3.4Å; H176-N179 WeakPolarHBondContact O-CB 3.16Å; H176-N179 PolarHBondContact O-N 2.91Å; H176-E180 VanDerWaalsContact O-CG 3.3Å; H176-E180 WeakPolarHBondContact O-CG 3.47Å; H176-E180 PolarHBondContact O-N 3.06Å; H176-T440 PolarHBondContact NE2-OG1 3.11Å
177	S	88.3	Confident	90	Very high	24 Å²	24	40.9 Å²	40.9	17%	0.168	20%	0.198	C	C	.	.	H	α-helix	trans	-71.9	-25.7	-176.7	-66.7	0	0	0	0	115.6	D173 F174 N179 S181 R334	D173-S177 PolarHBondContact O-N 3.25Å; F174-S177 PolarHBondContact O-N 3.36Å; S177-N179 VanDerWaalsContact C-N 3.35Å; S177-S181 VanDerWaalsContact O-CB 3.26Å; S177-S181 WeakPolarHBondContact O-CB 3.36Å; S177-S181 PolarHBondContact O-N 3.39Å; S177-R334 PolarHBondContact OG-NH1 3.02Å; S177-R334 PolarHBondContact OG-NH2 2.92Å
178	W	90.2	Very high	89.8	Confident	75 Å²	75	47.9 Å²	47.9	28%	0.284	23%	0.23	S	C	.	.	H	α-helix	trans	-60.4	-51.2	166.9	-176.2	-6.2	0	0	0	109.2	F174 H176 E180 S181 W182 L262	F174-W178 HydrophobicContact CD1-CE3 4.46Å; F174-W178 AromaticContact CE1-CE3 3.44Å; F174-W178 HydrophobicContact CE1-CE3 3.44Å; F174-W178 VanDerWaalsContact CE1-CE3 3.44Å; F174-W178 AromaticContact CE1-CZ3 3.85Å; F174-W178 HydrophobicContact CE1-CZ3 3.85Å; F174-W178 HydrophobicContact CE2-CE3 4.49Å; F174-W178 HydrophobicContact CZ-CD2 4.29Å; F174-W178 AromaticContact CZ-CE3 3.45Å; F174-W178 HydrophobicContact CZ-CE3 3.45Å; F174-W178 VanDerWaalsContact CZ-CE3 3.45Å; F174-W178 AromaticContact CZ-CZ3 3.91Å; F174-W178 HydrophobicContact CZ-CZ3 3.91Å; F174-W178 WeakPolarHBondContact O-CB 3.41Å; F174-W178 PolarHBondContact O-N 3.3Å; H176-W178 VanDerWaalsContact C-N 3.34Å; H176-W178 PolarHBondContact O-N 2.92Å; W178-E180 PolarHBondContact O-N 3.46Å; W178-S181 PolarHBondContact O-N 3.41Å; W178-W182 AromaticContact CD1-CD1 3.64Å; W178-W182 AromaticContact CD1-CD2 3.69Å; W178-W182 AromaticContact CD1-CE2 3.61Å; W178-W182 AromaticContact CD1-CG 3.77Å; W178-W182 AromaticContact CD1-NE1 3.53Å; W178-W182 AromaticContact CE2-CZ2 3.83Å; W178-W182 AromaticContact CZ2-CH2 3.83Å; W178-W182 HydrophobicContact CZ2-CH2 3.83Å; W178-W182 AromaticContact CZ2-CZ2 3.94Å; W178-W182 HydrophobicContact CZ2-CZ2 3.94Å; W178-W182 HydrophobicContact CZ2-CZ3 4.42Å; W178-W182 AromaticContact NE1-CD1 3.85Å; W178-W182 AromaticContact NE1-CD2 3.24Å; W178-W182 AromaticContact NE1-CE2 2.96Å; W178-W182 AromaticContact NE1-CE3 3.61Å; W178-W182 AromaticContact NE1-CG 3.84Å; W178-W182 AromaticContact NE1-CH2 3.52Å; W178-W182 AromaticContact NE1-CZ2 3.14Å; W178-W182 AromaticContact NE1-CZ3 3.73Å; W178-W182 AromaticContact NE1-NE1 3.34Å; W178-W182 PolarHBondContact O-N 3.39Å; W178-L262 HydrophobicContact CB-CD2 4.47Å; W178-L262 HydrophobicContact CD2-CD2 4.18Å; W178-L262 HydrophobicContact CG-CD2 3.97Å
179	N	91.5	Very high	89.3	Confident	3 Å²	3	49.9 Å²	49.9	2%	0.016	25%	0.251	C	S	.	.	H	α-helix	trans	-57.9	-49.4	178.4	-170.4	74.3	0	0	0	111.8	A175 H176 S177 S181 W182 V183 R258 L262 Q263	A175-N179 PolarHBondContact O-N 2.96Å; H176-N179 WeakPolarHBondContact O-CA 3.4Å; H176-N179 WeakPolarHBondContact O-CB 3.16Å; H176-N179 PolarHBondContact O-N 2.91Å; S177-N179 VanDerWaalsContact C-N 3.35Å; N179-S181 PolarHBondContact O-N 2.9Å; N179-W182 PolarHBondContact O-N 3.37Å; N179-V183 WeakPolarHBondContact O-CB 3.2Å; N179-V183 VanDerWaalsContact O-CG2 3.23Å; N179-V183 WeakPolarHBondContact O-CG2 3.49Å; N179-V183 PolarHBondContact O-N 3.3Å; N179-R258 PolarHBondContact ND2-O 3.3Å; N179-L262 HydrophobicContact CB-CB 4.48Å; N179-L262 HydrophobicContact CB-CD2 4.11Å; N179-Q263 VanDerWaalsContact CB-CD 3.44Å; N179-Q263 HydrophobicContact CB-CG 4.01Å; N179-Q263 PolarHBondContact ND2-NE2 2.94Å; N179-Q263 VanDerWaalsContact ND2-NE2 3.16Å
180	E	89	Confident	88.9	Confident	61 Å²	61	53 Å²	53	29%	0.285	27%	0.267	S	S	.	.	H	α-helix	trans	-57.8	-47.6	178.7	-63.2	178.3	157.8	0	0	112.2	H176 W178 W182 V183 E184 R258	H176-E180 VanDerWaalsContact O-CG 3.3Å; H176-E180 WeakPolarHBondContact O-CG 3.47Å; H176-E180 PolarHBondContact O-N 3.06Å; W178-E180 PolarHBondContact O-N 3.46Å; E180-W182 VanDerWaalsContact C-N 3.3Å; E180-W182 PolarHBondContact O-N 2.86Å; E180-V183 PolarHBondContact O-N 2.95Å; E180-E184 VanDerWaalsContact O-CB 3.31Å; E180-E184 WeakPolarHBondContact O-CB 3.31Å; E180-E184 PolarHBondContact O-N 3.5Å; E180-R258 HydrophobicContact CG-CB 4.09Å
181	S	89.1	Confident	88.7	Confident	40 Å²	40	55.4 Å²	55.4	28%	0.28	29%	0.285	S	S	.	.	H	α-helix	trans	-63	-36	-179.9	-177.3	0	0	0	0	112.8	S177 W178 N179 K185	S177-S181 VanDerWaalsContact O-CB 3.26Å; S177-S181 WeakPolarHBondContact O-CB 3.36Å; S177-S181 PolarHBondContact O-N 3.39Å; W178-S181 PolarHBondContact O-N 3.41Å; N179-S181 PolarHBondContact O-N 2.9Å; S181-K185 WeakPolarHBondContact O-CB 3.49Å; S181-K185 WeakPolarHBondContact O-CD 3.47Å; S181-K185 VanDerWaalsContact O-CG 3.23Å; S181-K185 WeakPolarHBondContact O-CG 3.09Å; S181-K185 PolarHBondContact O-N 3.02Å; S181-K185 PolarHBondContact OG-NZ 3.5Å
182	W	91.9	Very high	88.6	Confident	54 Å²	54	64 Å²	64	21%	0.205	32%	0.315	C	S	.	.	H	α-helix	trans	-79.8	-33.8	179.3	-80	27	0	0	0	112.3	W178 N179 E180 M186 W194 A197 L198 A201	W178-W182 AromaticContact CD1-CD1 3.64Å; W178-W182 AromaticContact CD1-CD2 3.69Å; W178-W182 AromaticContact CD1-CE2 3.61Å; W178-W182 AromaticContact CD1-CG 3.77Å; W178-W182 AromaticContact CD1-NE1 3.53Å; W178-W182 AromaticContact CE2-CZ2 3.83Å; W178-W182 AromaticContact CZ2-CH2 3.83Å; W178-W182 HydrophobicContact CZ2-CH2 3.83Å; W178-W182 AromaticContact CZ2-CZ2 3.94Å; W178-W182 HydrophobicContact CZ2-CZ2 3.94Å; W178-W182 HydrophobicContact CZ2-CZ3 4.42Å; W178-W182 AromaticContact NE1-CD1 3.85Å; W178-W182 AromaticContact NE1-CD2 3.24Å; W178-W182 AromaticContact NE1-CE2 2.96Å; W178-W182 AromaticContact NE1-CE3 3.61Å; W178-W182 AromaticContact NE1-CG 3.84Å; W178-W182 AromaticContact NE1-CH2 3.52Å; W178-W182 AromaticContact NE1-CZ2 3.14Å; W178-W182 AromaticContact NE1-CZ3 3.73Å; W178-W182 AromaticContact NE1-NE1 3.34Å; W178-W182 PolarHBondContact O-N 3.39Å; N179-W182 PolarHBondContact O-N 3.37Å; E180-W182 VanDerWaalsContact C-N 3.3Å; E180-W182 PolarHBondContact O-N 2.86Å; W182-M186 WeakPolarHBondContact O-CB 3.49Å; W182-M186 PolarHBondContact O-N 3.49Å; W182-W194 HydrophobicContact CB-CE3 4.41Å; W182-W194 AromaticContact CD1-CZ3 3.74Å; W182-W194 HydrophobicContact CD2-CE3 4.1Å; W182-W194 AromaticContact CD2-CZ3 3.97Å; W182-W194 HydrophobicContact CD2-CZ3 3.97Å; W182-W194 AromaticContact CE2-CZ3 3.77Å; W182-W194 AromaticContact CG-CE3 3.99Å; W182-W194 HydrophobicContact CG-CE3 3.99Å; W182-W194 AromaticContact CG-CZ3 3.93Å; W182-W194 HydrophobicContact CG-CZ3 3.93Å; W182-W194 HydrophobicContact CZ2-CZ3 4.45Å; W182-W194 AromaticContact NE1-CZ3 3.64Å; W182-A197 HydrophobicContact CE3-CB 4.17Å; W182-A197 HydrophobicContact CH2-CB 4.24Å; W182-A197 HydrophobicContact CZ3-CB 3.8Å; W182-A197 WeakPolarHBondContact CZ3-O 3.14Å; W182-L198 HydrophobicContact CB-CD1 4.4Å; W182-L198 HydrophobicContact CE3-CB 4.31Å; W182-L198 HydrophobicContact CE3-CD1 4.16Å; W182-A201 HydrophobicContact CH2-CB 4.39Å; W182-A201 HydrophobicContact CZ3-CB 3.95Å
183	V	89.6	Confident	88.7	Confident	19 Å²	19	67.3 Å²	67.3	12%	0.115	34%	0.338	C	S	.	.	H	α-helix	trans	-66	-46	172.9	170.1	0	0	0	0	110.4	N179 E180 K185 M186 E187 L198	N179-V183 WeakPolarHBondContact O-CB 3.2Å; N179-V183 VanDerWaalsContact O-CG2 3.23Å; N179-V183 WeakPolarHBondContact O-CG2 3.49Å; N179-V183 PolarHBondContact O-N 3.3Å; E180-V183 PolarHBondContact O-N 2.95Å; V183-K185 PolarHBondContact O-N 3.34Å; V183-M186 HydrophobicContact CG1-CE 4.42Å; V183-M186 WeakPolarHBondContact O-CA 3.12Å; V183-M186 VanDerWaalsContact O-CB 3.29Å; V183-M186 WeakPolarHBondContact O-CB 3.37Å; V183-M186 PolarHBondContact O-N 3.28Å; V183-E187 WeakPolarHBondContact O-CG 3.49Å; V183-E187 PolarHBondContact O-N 2.84Å; V183-L198 HydrophobicContact CG2-CD2 4.35Å
184	E	88.9	Confident	88.8	Confident	80 Å²	80	69.6 Å²	69.6	37%	0.374	35%	0.345	S	S	.	.	H	α-helix	trans	-59	-46.2	175.9	-176.6	176.2	-148.3	0	0	111.6	E180 M186 E187 E188	E180-E184 VanDerWaalsContact O-CB 3.31Å; E180-E184 WeakPolarHBondContact O-CB 3.31Å; E180-E184 PolarHBondContact O-N 3.5Å; E184-M186 PolarHBondContact O-N 3.19Å; E184-E187 PolarHBondContact O-N 2.88Å; E184-E187 VanDerWaalsContact O-N 3.11Å; E184-E188 PolarHBondContact O-N 3.47Å
185	K	89.4	Confident	88.8	Confident	82 Å²	82	72.5 Å²	72.5	36%	0.357	35%	0.354	S	S	.	.	H	α-helix	trans	-65.8	-25.4	175.1	-72.7	172	-175.3	160.4	0	114	S181 V183 G189 W194	S181-K185 WeakPolarHBondContact O-CB 3.49Å; S181-K185 WeakPolarHBondContact O-CD 3.47Å; S181-K185 VanDerWaalsContact O-CG 3.23Å; S181-K185 WeakPolarHBondContact O-CG 3.09Å; S181-K185 PolarHBondContact O-N 3.02Å; S181-K185 PolarHBondContact OG-NZ 3.5Å; V183-K185 PolarHBondContact O-N 3.34Å; K185-G189 VanDerWaalsContact O-CA 3.22Å; K185-G189 WeakPolarHBondContact O-CA 3.37Å; K185-G189 PolarHBondContact O-N 3.07Å; K185-W194 HydrophobicContact CB-CD2 3.82Å; K185-W194 HydrophobicContact CB-CE3 4.37Å; K185-W194 HydrophobicContact CB-CG 4.05Å; K185-W194 HydrophobicContact CB-CZ2 4.18Å; K185-W194 HydrophobicContact CD-CD2 4.46Å; K185-W194 HydrophobicContact CD-CE3 4.49Å; K185-W194 HydrophobicContact CD-CH2 3.64Å; K185-W194 HydrophobicContact CD-CZ2 3.56Å; K185-W194 HydrophobicContact CD-CZ3 4.12Å; K185-W194 HydrophobicContact CG-CZ2 4.39Å
186	M	89.2	Confident	88.9	Confident	44 Å²	44	75.1 Å²	75.1	22%	0.217	38%	0.376	C	S	.	.	H	α-helix	trans	-73.6	-37.5	173.2	-179.5	-167.2	68.8	0	0	111.1	W182 V183 E184 S191 W194 Y195	W182-M186 WeakPolarHBondContact O-CB 3.49Å; W182-M186 PolarHBondContact O-N 3.49Å; V183-M186 HydrophobicContact CG1-CE 4.42Å; V183-M186 WeakPolarHBondContact O-CA 3.12Å; V183-M186 VanDerWaalsContact O-CB 3.29Å; V183-M186 WeakPolarHBondContact O-CB 3.37Å; V183-M186 PolarHBondContact O-N 3.28Å; E184-M186 PolarHBondContact O-N 3.19Å; M186-S191 WeakPolarHBondContact O-CA 3.3Å; M186-S191 WeakPolarHBondContact O-CB 3.44Å; M186-W194 HydrophobicContact CB-CB 3.73Å; M186-W194 HydrophobicContact CG-CB 4.29Å; M186-Y195 HydrophobicContact SD-CD2 3.96Å
187	E	88	Confident	89.1	Confident	142 Å²	142	75.1 Å²	75.1	66%	0.664	38%	0.38	S	S	*	.	H	α-helix	trans	-73.2	-41.9	178.2	-70.4	176	172.9	0	0	112.2	V183 E184	V183-E187 WeakPolarHBondContact O-CG 3.49Å; V183-E187 PolarHBondContact O-N 2.84Å; E184-E187 PolarHBondContact O-N 2.88Å; E184-E187 VanDerWaalsContact O-N 3.11Å
188	E	88.7	Confident	89.3	Confident	155 Å²	155	75.3 Å²	75.3	72%	0.724	38%	0.379	S	S	*	.	H	α-helix	trans	-87.9	-27.5	-178.2	-63.3	-177.2	161.2	0	0	113.9	E184	E184-E188 PolarHBondContact O-N 3.47Å
189	G	80.4	Confident	89.5	Confident	44 Å²	44	76.5 Å²	76.5	45%	0.454	39%	0.391	S	S	.	.	S	Bend	trans	-108.3	-153	-168.3	0	0	0	0	0	114.6	K185 S191	K185-G189 VanDerWaalsContact O-CA 3.22Å; K185-G189 WeakPolarHBondContact O-CA 3.37Å; K185-G189 PolarHBondContact O-N 3.07Å; G189-S191 PolarHBondContact O-N 3.44Å
190	N	81.2	Confident	89.7	Confident	109 Å²	109	79.7 Å²	79.7	58%	0.583	41%	0.413	S	S	*	.			trans	-73.6	91.5	173.3	-174.6	-4.1	0	0	0	110.1	R192 C193 W194	N190-R192 PolarHBondContact O-N 2.9Å; N190-R192 VanDerWaalsContact O-N 3.11Å; N190-C193 HydrophobicContact CB-CB 4.47Å; N190-C193 PolarHBondContact O-N 3.21Å; N190-C193 VanDerWaalsContact O-N 3.09Å; N190-W194 PolarHBondContact O-N 3.19Å
191	S	85.9	Confident	90	Very high	65 Å²	65	77.5 Å²	77.5	46%	0.455	41%	0.406	S	S	.	.	H	α-helix	trans	-49	-40.3	-174.8	60.8	0	0	0	0	113.8	M186 G189 C193 Y195	M186-S191 WeakPolarHBondContact O-CA 3.3Å; M186-S191 WeakPolarHBondContact O-CB 3.44Å; G189-S191 PolarHBondContact O-N 3.44Å; S191-C193 PolarHBondContact O-N 3.42Å; S191-Y195 WeakPolarHBondContact O-CB 3.37Å; S191-Y195 PolarHBondContact O-N 3.5Å
192	R	89.9	Confident	90.3	Very high	209 Å²	209	76.1 Å²	76.1	79%	0.789	40%	0.395	S	S	*	.	H	α-helix	trans	-66	-40.3	-177.9	-66.3	-174.3	-179.9	179.6	1	113.2	N190 A196	N190-R192 PolarHBondContact O-N 2.9Å; N190-R192 VanDerWaalsContact O-N 3.11Å; R192-A196 VanDerWaalsContact O-CB 3.32Å; R192-A196 WeakPolarHBondContact O-CB 3.4Å; R192-A196 PolarHBondContact O-N 2.97Å
193	C	91.8	Very high	90.5	Very high	79 Å²	79	76.2 Å²	76.2	53%	0.534	41%	0.408	S	S	.	.	H	α-helix	trans	-69.8	-45.9	-177.5	-174.2	0	0	0	0	111	N190 S191 A196 A197	N190-C193 HydrophobicContact CB-CB 4.47Å; N190-C193 PolarHBondContact O-N 3.21Å; N190-C193 VanDerWaalsContact O-N 3.09Å; S191-C193 PolarHBondContact O-N 3.42Å; C193-A196 PolarHBondContact O-N 3.25Å; C193-A197 WeakPolarHBondContact O-CB 3.39Å; C193-A197 PolarHBondContact O-N 3.09Å
194	W	91.1	Very high	90.9	Very high	74 Å²	74	80.6 Å²	80.6	28%	0.28	43%	0.43	S	S	.	.	H	α-helix	trans	-71.4	-35.9	179.7	-72.2	109	0	0	0	112.5	W182 K185 M186 N190 A197 L198	W182-W194 HydrophobicContact CB-CE3 4.41Å; W182-W194 AromaticContact CD1-CZ3 3.74Å; W182-W194 HydrophobicContact CD2-CE3 4.1Å; W182-W194 AromaticContact CD2-CZ3 3.97Å; W182-W194 HydrophobicContact CD2-CZ3 3.97Å; W182-W194 AromaticContact CE2-CZ3 3.77Å; W182-W194 AromaticContact CG-CE3 3.99Å; W182-W194 HydrophobicContact CG-CE3 3.99Å; W182-W194 AromaticContact CG-CZ3 3.93Å; W182-W194 HydrophobicContact CG-CZ3 3.93Å; W182-W194 HydrophobicContact CZ2-CZ3 4.45Å; W182-W194 AromaticContact NE1-CZ3 3.64Å; K185-W194 HydrophobicContact CB-CD2 3.82Å; K185-W194 HydrophobicContact CB-CE3 4.37Å; K185-W194 HydrophobicContact CB-CG 4.05Å; K185-W194 HydrophobicContact CB-CZ2 4.18Å; K185-W194 HydrophobicContact CD-CD2 4.46Å; K185-W194 HydrophobicContact CD-CE3 4.49Å; K185-W194 HydrophobicContact CD-CH2 3.64Å; K185-W194 HydrophobicContact CD-CZ2 3.56Å; K185-W194 HydrophobicContact CD-CZ3 4.12Å; K185-W194 HydrophobicContact CG-CZ2 4.39Å; M186-W194 HydrophobicContact CB-CB 3.73Å; M186-W194 HydrophobicContact CG-CB 4.29Å; N190-W194 PolarHBondContact O-N 3.19Å; W194-A197 PolarHBondContact O-N 2.78Å; W194-L198 WeakPolarHBondContact O-CB 3.14Å; W194-L198 PolarHBondContact O-N 2.82Å
195	Y	90.8	Very high	91.2	Very high	138 Å²	138	78.1 Å²	78.1	54%	0.541	42%	0.419	S	S	.	.	H	α-helix	trans	-60.9	-46.5	170.9	-176.2	-96.5	0	0	0	111.8	M186 S191 A197 L198 L199	M186-Y195 HydrophobicContact SD-CD2 3.96Å; S191-Y195 WeakPolarHBondContact O-CB 3.37Å; S191-Y195 PolarHBondContact O-N 3.5Å; Y195-A197 VanDerWaalsContact C-N 3.34Å; Y195-A197 PolarHBondContact O-N 3.49Å; Y195-L198 PolarHBondContact O-N 3.06Å; Y195-L199 HydrophobicContact CE1-CD2 4.44Å; Y195-L199 WeakPolarHBondContact O-CB 3.43Å; Y195-L199 PolarHBondContact O-N 2.63Å
196	A	93.4	Very high	91.6	Very high	57 Å²	57	77 Å²	77	47%	0.471	41%	0.413	S	S	.	.	H	α-helix	trans	-62.2	-40.7	175.7	0	0	0	0	0	111.9	R192 C193 S200	R192-A196 VanDerWaalsContact O-CB 3.32Å; R192-A196 WeakPolarHBondContact O-CB 3.4Å; R192-A196 PolarHBondContact O-N 2.97Å; C193-A196 PolarHBondContact O-N 3.25Å; A196-S200 VanDerWaalsContact O-CB 3.23Å; A196-S200 WeakPolarHBondContact O-CB 3.09Å; A196-S200 PolarHBondContact O-N 3.12Å; A196-S200 PolarHBondContact O-OG 3.31Å
197	A	93.3	Very high	92	Very high	23 Å²	23	79.9 Å²	79.9	19%	0.19	43%	0.429	C	S	.	.	H	α-helix	trans	-60.9	-50.6	175.5	0	0	0	0	0	111.3	W182 C193 W194 Y195 L199 S200 A201	W182-A197 HydrophobicContact CE3-CB 4.17Å; W182-A197 HydrophobicContact CH2-CB 4.24Å; W182-A197 HydrophobicContact CZ3-CB 3.8Å; W182-A197 WeakPolarHBondContact CZ3-O 3.14Å; C193-A197 WeakPolarHBondContact O-CB 3.39Å; C193-A197 PolarHBondContact O-N 3.09Å; W194-A197 PolarHBondContact O-N 2.78Å; Y195-A197 VanDerWaalsContact C-N 3.34Å; Y195-A197 PolarHBondContact O-N 3.49Å; A197-L199 PolarHBondContact O-N 3.36Å; A197-S200 PolarHBondContact O-N 3.39Å; A197-S200 PolarHBondContact O-OG 2.89Å; A197-A201 PolarHBondContact O-N 3.37Å
198	L	92.9	Very high	92.4	Very high	29 Å²	29	77.8 Å²	77.8	15%	0.152	42%	0.422	C	S	.	.	H	α-helix	trans	-58.9	-46.4	179.5	-172.1	69.5	0	0	0	112	W182 V183 W194 Y195 T202 L262	W182-L198 HydrophobicContact CB-CD1 4.4Å; W182-L198 HydrophobicContact CE3-CB 4.31Å; W182-L198 HydrophobicContact CE3-CD1 4.16Å; V183-L198 HydrophobicContact CG2-CD2 4.35Å; W194-L198 WeakPolarHBondContact O-CB 3.14Å; W194-L198 PolarHBondContact O-N 2.82Å; Y195-L198 PolarHBondContact O-N 3.06Å; L198-T202 WeakPolarHBondContact O-CB 3.36Å; L198-T202 PolarHBondContact O-N 3.13Å; L198-T202 VanDerWaalsContact O-N 3.07Å; L198-T202 PolarHBondContact O-OG1 3.38Å; L198-L262 HydrophobicContact CD1-CB 3.96Å; L198-L262 HydrophobicContact CD1-CD1 4.49Å; L198-L262 HydrophobicContact CD1-CD2 3.76Å; L198-L262 HydrophobicContact CD1-CG 4.27Å
199	L	93.4	Very high	92.8	Very high	99 Å²	99	70.5 Å²	70.5	52%	0.518	39%	0.388	S	S	.	.	H	α-helix	trans	-64	-42.6	177.3	-176.4	62.8	0	0	0	111.4	Y195 A197 T202 A203	Y195-L199 HydrophobicContact CE1-CD2 4.44Å; Y195-L199 WeakPolarHBondContact O-CB 3.43Å; Y195-L199 PolarHBondContact O-N 2.63Å; A197-L199 PolarHBondContact O-N 3.36Å; L199-T202 PolarHBondContact O-N 3.17Å; L199-A203 VanDerWaalsContact O-CB 3.25Å; L199-A203 WeakPolarHBondContact O-CB 3.42Å; L199-A203 PolarHBondContact O-N 2.94Å
200	S	95.1	Very high	93.5	Very high	71 Å²	71	73.5 Å²	73.5	50%	0.497	39%	0.393	S	S	.	.	H	α-helix	trans	-64.8	-43.2	179.9	72.1	0	0	0	0	112.6	A196 A197 A203 L204	A196-S200 VanDerWaalsContact O-CB 3.23Å; A196-S200 WeakPolarHBondContact O-CB 3.09Å; A196-S200 PolarHBondContact O-N 3.12Å; A196-S200 PolarHBondContact O-OG 3.31Å; A197-S200 PolarHBondContact O-N 3.39Å; A197-S200 PolarHBondContact O-OG 2.89Å; S200-A203 PolarHBondContact O-N 3.36Å; S200-L204 VanDerWaalsContact O-CB 3.27Å; S200-L204 WeakPolarHBondContact O-CB 3.36Å; S200-L204 PolarHBondContact O-N 2.96Å
201	A	95.5	Very high	94.3	Very high	15 Å²	15	71.6 Å²	71.6	12%	0.124	39%	0.386	C	S	.	.	H	α-helix	trans	-64.4	-44.1	177.5	0	0	0	0	0	111.2	W182 A197 L204 N205 L262	W182-A201 HydrophobicContact CH2-CB 4.39Å; W182-A201 HydrophobicContact CZ3-CB 3.95Å; A197-A201 PolarHBondContact O-N 3.37Å; A201-L204 PolarHBondContact O-N 2.93Å; A201-N205 VanDerWaalsContact O-CG 3.31Å; A201-N205 PolarHBondContact O-N 3.38Å; A201-N205 PolarHBondContact O-ND2 3.15Å; A201-L262 HydrophobicContact CB-CD1 3.76Å
202	T	95.6	Very high	94.7	Very high	10 Å²	10	69.3 Å²	69.3	6%	0.061	37%	0.371	C	S	.	.	H	α-helix	trans	-63.3	-47.1	177.5	-54.9	0	0	0	0	111.5	L198 L199 L204 N205 Y206 L261	L198-T202 WeakPolarHBondContact O-CB 3.36Å; L198-T202 PolarHBondContact O-N 3.13Å; L198-T202 VanDerWaalsContact O-N 3.07Å; L198-T202 PolarHBondContact O-OG1 3.38Å; L199-T202 PolarHBondContact O-N 3.17Å; T202-L204 PolarHBondContact O-N 3.34Å; T202-N205 PolarHBondContact O-N 2.86Å; T202-Y206 HydrophobicContact CG2-CD2 3.93Å; T202-Y206 HydrophobicContact CG2-CE2 3.69Å; T202-Y206 VanDerWaalsContact O-CD2 3.27Å; T202-Y206 WeakPolarHBondContact O-CD2 3.2Å; T202-Y206 PolarHBondContact O-N 3.23Å; T202-Y206 VanDerWaalsContact O-N 3.12Å; T202-L261 HydrophobicContact CG2-CB 3.94Å; T202-L261 HydrophobicContact CG2-CD2 3.66Å; T202-L261 HydrophobicContact CG2-CG 3.77Å
203	A	96.5	Very high	95	Very high	56 Å²	56	60.4 Å²	60.4	46%	0.463	34%	0.338	S	S	.	.	H	α-helix	trans	-63.1	-41.7	178.7	0	0	0	0	0	112	L199 S200 Y206 L207	L199-A203 VanDerWaalsContact O-CB 3.25Å; L199-A203 WeakPolarHBondContact O-CB 3.42Å; L199-A203 PolarHBondContact O-N 2.94Å; S200-A203 PolarHBondContact O-N 3.36Å; A203-Y206 PolarHBondContact O-N 3.48Å; A203-L207 VanDerWaalsContact O-CB 3.29Å; A203-L207 WeakPolarHBondContact O-CB 3.48Å; A203-L207 PolarHBondContact O-N 2.99Å
204	L	97.1	Very high	95.2	Very high	111 Å²	111	60.5 Å²	60.5	58%	0.581	34%	0.336	S	S	*	.	H	α-helix	trans	-61.4	-45.2	177	-179.4	64.8	0	0	0	111.6	S200 A201 T202 L207 L208	S200-L204 VanDerWaalsContact O-CB 3.27Å; S200-L204 WeakPolarHBondContact O-CB 3.36Å; S200-L204 PolarHBondContact O-N 2.96Å; A201-L204 PolarHBondContact O-N 2.93Å; T202-L204 PolarHBondContact O-N 3.34Å; L204-L207 PolarHBondContact O-N 2.86Å; L204-L208 WeakPolarHBondContact O-CB 3.44Å; L204-L208 PolarHBondContact O-N 2.9Å
205	N	96.9	Very high	95.3	Very high	29 Å²	29	60.7 Å²	60.7	16%	0.155	34%	0.342	C	S	.	.	H	α-helix	trans	-62.7	-44.3	179.1	-75.7	-24.8	0	0	0	112.2	A201 T202 L208 S209 S265 V269	A201-N205 VanDerWaalsContact O-CG 3.31Å; A201-N205 PolarHBondContact O-N 3.38Å; A201-N205 PolarHBondContact O-ND2 3.15Å; T202-N205 PolarHBondContact O-N 2.86Å; N205-L208 PolarHBondContact O-N 3.41Å; N205-S209 WeakPolarHBondContact O-CB 3.49Å; N205-S209 PolarHBondContact O-N 2.8Å; N205-S209 PolarHBondContact O-OG 3.33Å; N205-S265 WeakPolarHBondContact CB-OG 3.34Å; N205-S265 PolarHBondContact ND2-OG 2.99Å; N205-S265 VanDerWaalsContact ND2-OG 3.09Å; N205-V269 HydrophobicContact CB-CG2 3.69Å; N205-V269 WeakPolarHBondContact O-CG2 3.49Å
206	Y	97.4	Very high	95.4	Very high	58 Å²	58	54.8 Å²	54.8	23%	0.227	32%	0.319	C	S	.	.	H	α-helix	trans	-68.6	-38.1	175.9	-77.1	-61	0	0	0	113.1	T202 A203 L208 S209 L210 S244 L261 S264 S265	T202-Y206 HydrophobicContact CG2-CD2 3.93Å; T202-Y206 HydrophobicContact CG2-CE2 3.69Å; T202-Y206 VanDerWaalsContact O-CD2 3.27Å; T202-Y206 WeakPolarHBondContact O-CD2 3.2Å; T202-Y206 PolarHBondContact O-N 3.23Å; T202-Y206 VanDerWaalsContact O-N 3.12Å; A203-Y206 PolarHBondContact O-N 3.48Å; Y206-L208 VanDerWaalsContact C-N 3.35Å; Y206-S209 PolarHBondContact O-N 2.87Å; Y206-L210 WeakPolarHBondContact O-CB 3.45Å; Y206-L210 PolarHBondContact O-N 3.27Å; Y206-S244 WeakPolarHBondContact OH-CB 3.37Å; Y206-S244 PolarHBondContact OH-OG 3.33Å; Y206-L261 HydrophobicContact CD2-CD2 4.46Å; Y206-L261 HydrophobicContact CE2-CD1 4.13Å; Y206-L261 HydrophobicContact CE2-CD2 3.66Å; Y206-L261 HydrophobicContact CE2-CG 3.61Å; Y206-L261 VanDerWaalsContact OH-CD1 3.26Å; Y206-L261 WeakPolarHBondContact OH-CD1 3.38Å; Y206-S264 PolarHBondContact OH-OG 3.1Å; Y206-S264 VanDerWaalsContact OH-OG 3.13Å; Y206-S265 VanDerWaalsContact CE2-CB 3.47Å
207	L	97	Very high	95.4	Very high	105 Å²	105	55.4 Å²	55.4	55%	0.55	31%	0.312	S	S	.	.	H	α-helix	trans	-61.4	-46.3	175.4	-179.6	62.6	0	0	0	110.7	A203 L204 S209 L210 V211	A203-L207 VanDerWaalsContact O-CB 3.29Å; A203-L207 WeakPolarHBondContact O-CB 3.48Å; A203-L207 PolarHBondContact O-N 2.99Å; L204-L207 PolarHBondContact O-N 2.86Å; L207-S209 VanDerWaalsContact C-N 3.31Å; L207-S209 PolarHBondContact O-N 3.5Å; L207-L210 PolarHBondContact O-N 3.26Å; L207-V211 HydrophobicContact CD1-CG2 4.42Å; L207-V211 VanDerWaalsContact O-CG2 3.31Å; L207-V211 WeakPolarHBondContact O-CG2 3.17Å; L207-V211 PolarHBondContact O-N 3.44Å
208	L	96.5	Very high	95.3	Very high	97 Å²	97	58.8 Å²	58.8	51%	0.508	33%	0.33	S	S	.	.	H	α-helix	trans	-60	-42.7	176	179.2	61.5	0	0	0	111.5	L204 N205 Y206 V211 A212 V269	L204-L208 WeakPolarHBondContact O-CB 3.44Å; L204-L208 PolarHBondContact O-N 2.9Å; N205-L208 PolarHBondContact O-N 3.41Å; Y206-L208 VanDerWaalsContact C-N 3.35Å; L208-V211 PolarHBondContact O-N 3.14Å; L208-A212 WeakPolarHBondContact O-CB 3.44Å; L208-A212 PolarHBondContact O-N 3.42Å; L208-V269 HydrophobicContact CD2-CG1 3.94Å; L208-V269 HydrophobicContact CD2-CG2 4.48Å
209	S	96.7	Very high	95.1	Very high	3 Å²	3	61.9 Å²	61.9	2%	0.021	34%	0.34	C	S	.	.	H	α-helix	trans	-64.4	-42.7	177.4	-58.2	0	0	0	0	112.3	N205 Y206 L207 A212 I213 T268 V269	N205-S209 WeakPolarHBondContact O-CB 3.49Å; N205-S209 PolarHBondContact O-N 2.8Å; N205-S209 PolarHBondContact O-OG 3.33Å; Y206-S209 PolarHBondContact O-N 2.87Å; L207-S209 VanDerWaalsContact C-N 3.31Å; L207-S209 PolarHBondContact O-N 3.5Å; S209-A212 WeakPolarHBondContact O-CB 3.42Å; S209-A212 PolarHBondContact O-N 3.04Å; S209-I213 VanDerWaalsContact O-CG1 3.29Å; S209-I213 WeakPolarHBondContact O-CG1 3.39Å; S209-I213 PolarHBondContact O-N 3.15Å; S209-T268 WeakPolarHBondContact OG-CG2 3.43Å; S209-V269 WeakPolarHBondContact OG-CA 3.38Å; S209-V269 WeakPolarHBondContact OG-CG2 3.29Å; S209-V269 PolarHBondContact OG-N 3.32Å
210	L	96.4	Very high	94.8	Very high	106 Å²	106	57.7 Å²	57.7	56%	0.555	32%	0.317	S	S	*	.	H	α-helix	trans	-63.7	-46.5	177.5	-177	68.3	0	0	0	111.2	Y206 L207 A212 I213 V214	Y206-L210 WeakPolarHBondContact O-CB 3.45Å; Y206-L210 PolarHBondContact O-N 3.27Å; L207-L210 PolarHBondContact O-N 3.26Å; L210-A212 VanDerWaalsContact C-N 3.31Å; L210-A212 PolarHBondContact O-N 3.44Å; L210-I213 PolarHBondContact O-N 3.37Å; L210-V214 WeakPolarHBondContact O-CG2 3.43Å; L210-V214 PolarHBondContact O-N 3.21Å
211	V	96.5	Very high	94.6	Very high	70 Å²	70	55.2 Å²	55.2	42%	0.424	30%	0.3	S	S	.	.	H	α-helix	trans	-59.2	-45	175.2	171.3	0	0	0	0	110.2	L207 L208 I213 V214 L215	L207-V211 HydrophobicContact CD1-CG2 4.42Å; L207-V211 VanDerWaalsContact O-CG2 3.31Å; L207-V211 WeakPolarHBondContact O-CG2 3.17Å; L207-V211 PolarHBondContact O-N 3.44Å; L208-V211 PolarHBondContact O-N 3.14Å; V211-I213 PolarHBondContact O-N 2.97Å; V211-V214 PolarHBondContact O-N 3.49Å; V211-L215 HydrophobicContact CG1-CD1 3.79Å; V211-L215 HydrophobicContact CG1-CG 4.27Å; V211-L215 VanDerWaalsContact O-CG 3.24Å; V211-L215 WeakPolarHBondContact O-CG 3.5Å; V211-L215 PolarHBondContact O-N 2.68Å
212	A	95.1	Very high	94.1	Very high	17 Å²	17	58.8 Å²	58.8	14%	0.14	31%	0.313	C	S	.	.	H	α-helix	trans	-58.4	-48	177.1	0	0	0	0	0	112	L208 S209 L210 V214 L215 F216 M272	L208-A212 WeakPolarHBondContact O-CB 3.44Å; L208-A212 PolarHBondContact O-N 3.42Å; S209-A212 WeakPolarHBondContact O-CB 3.42Å; S209-A212 PolarHBondContact O-N 3.04Å; L210-A212 VanDerWaalsContact C-N 3.31Å; L210-A212 PolarHBondContact O-N 3.44Å; A212-V214 PolarHBondContact O-N 3.41Å; A212-L215 PolarHBondContact O-N 2.89Å; A212-F216 HydrophobicContact CB-CE1 4.25Å; A212-F216 HydrophobicContact CB-CE2 4.06Å; A212-F216 HydrophobicContact CB-CZ 3.72Å; A212-F216 WeakPolarHBondContact O-CD1 3.49Å; A212-F216 WeakPolarHBondContact O-CD2 3.37Å; A212-F216 WeakPolarHBondContact O-CG 3.41Å; A212-F216 PolarHBondContact O-N 3.37Å; A212-M272 HydrophobicContact CB-CB 4.15Å; A212-M272 HydrophobicContact CB-CG 4.44Å
213	I	95.9	Very high	93.5	Very high	22 Å²	22	64.3 Å²	64.3	11%	0.113	35%	0.349	C	S	.	.	H	α-helix	trans	-57.8	-46.2	177.2	-68.4	164.7	0	0	0	111.5	S209 L210 V211 L215 F216 F217 I233 M237 M272	S209-I213 VanDerWaalsContact O-CG1 3.29Å; S209-I213 WeakPolarHBondContact O-CG1 3.39Å; S209-I213 PolarHBondContact O-N 3.15Å; L210-I213 PolarHBondContact O-N 3.37Å; V211-I213 PolarHBondContact O-N 2.97Å; I213-L215 PolarHBondContact O-N 2.9Å; I213-F216 PolarHBondContact O-N 3.21Å; I213-F217 HydrophobicContact CG2-CD2 3.82Å; I213-F217 HydrophobicContact CG2-CE2 3.72Å; I213-F217 WeakPolarHBondContact O-CD2 3.34Å; I213-F217 PolarHBondContact O-N 3.48Å; I213-I233 HydrophobicContact CG2-CG2 4.18Å; I213-M237 HydrophobicContact CD1-CB 4.3Å; I213-M237 HydrophobicContact CD1-CG 4.14Å; I213-M237 HydrophobicContact CG2-SD 4.32Å; I213-M272 HydrophobicContact CD1-SD 3.89Å; I213-M272 HydrophobicContact CG1-CG 4.4Å; I213-M272 HydrophobicContact CG1-SD 3.38Å; I213-M272 WeakPolarHBondContact CG1-SD 3.42Å
214	V	95.4	Very high	92.8	Very high	80 Å²	80	66.7 Å²	66.7	49%	0.485	37%	0.369	S	S	.	.	H	α-helix	trans	-61	-46.7	178.2	172.8	0	0	0	0	110.6	L210 V211 A212 F216 F217 V218	L210-V214 WeakPolarHBondContact O-CG2 3.43Å; L210-V214 PolarHBondContact O-N 3.21Å; V211-V214 PolarHBondContact O-N 3.49Å; A212-V214 PolarHBondContact O-N 3.41Å; V214-F216 VanDerWaalsContact C-N 3.3Å; V214-F216 PolarHBondContact O-N 3.33Å; V214-F217 PolarHBondContact O-N 3.29Å; V214-V218 HydrophobicContact CG1-CG2 4.46Å; V214-V218 VanDerWaalsContact O-CG2 3.3Å; V214-V218 WeakPolarHBondContact O-CG2 3.45Å; V214-V218 PolarHBondContact O-N 2.91Å
215	L	93.2	Very high	92.2	Very high	79 Å²	79	64 Å²	64	41%	0.414	36%	0.36	S	S	.	.	H	α-helix	trans	-62.5	-37.2	177.4	-65.4	171.6	0	0	0	111.8	V211 A212 I213 V218 Y219	V211-L215 HydrophobicContact CG1-CD1 3.79Å; V211-L215 HydrophobicContact CG1-CG 4.27Å; V211-L215 VanDerWaalsContact O-CG 3.24Å; V211-L215 WeakPolarHBondContact O-CG 3.5Å; V211-L215 PolarHBondContact O-N 2.68Å; A212-L215 PolarHBondContact O-N 2.89Å; I213-L215 PolarHBondContact O-N 2.9Å; L215-V218 PolarHBondContact O-N 3.38Å; L215-Y219 HydrophobicContact CB-CD2 4.31Å; L215-Y219 HydrophobicContact CD2-CD2 4.26Å; L215-Y219 HydrophobicContact CD2-CE2 3.71Å; L215-Y219 VanDerWaalsContact O-CD2 3.31Å; L215-Y219 WeakPolarHBondContact O-CD2 3.38Å; L215-Y219 PolarHBondContact O-N 3.47Å
216	F	93.8	Very high	91.8	Very high	13 Å²	13	63.1 Å²	63.1	6%	0.057	36%	0.356	C	S	.	.	H	α-helix	trans	-63.9	-46.1	177.2	-59.7	-18.2	0	0	0	111.8	A212 I213 V214 V218 Y220 I233 M272 W276 M279	A212-F216 HydrophobicContact CB-CE1 4.25Å; A212-F216 HydrophobicContact CB-CE2 4.06Å; A212-F216 HydrophobicContact CB-CZ 3.72Å; A212-F216 WeakPolarHBondContact O-CD1 3.49Å; A212-F216 WeakPolarHBondContact O-CD2 3.37Å; A212-F216 WeakPolarHBondContact O-CG 3.41Å; A212-F216 PolarHBondContact O-N 3.37Å; I213-F216 PolarHBondContact O-N 3.21Å; V214-F216 VanDerWaalsContact C-N 3.3Å; V214-F216 PolarHBondContact O-N 3.33Å; F216-V218 VanDerWaalsContact C-N 3.32Å; F216-V218 PolarHBondContact O-N 3.09Å; F216-Y220 HydrophobicContact CD1-CD2 4.48Å; F216-Y220 WeakPolarHBondContact O-CA 3.33Å; F216-Y220 WeakPolarHBondContact O-CB 3.37Å; F216-Y220 PolarHBondContact O-N 2.92Å; F216-I233 HydrophobicContact CB-CD1 3.54Å; F216-I233 HydrophobicContact CB-CG1 3.89Å; F216-I233 HydrophobicContact CB-CG2 4.41Å; F216-I233 HydrophobicContact CD2-CG1 4.41Å; F216-M272 HydrophobicContact CE2-CB 4.02Å; F216-M272 WeakPolarHBondContact CE2-O 3.23Å; F216-M272 HydrophobicContact CE2-SD 4.04Å; F216-M272 HydrophobicContact CZ-CB 4.31Å; F216-M272 WeakPolarHBondContact CZ-O 3.47Å; F216-W276 HydrophobicContact CE1-CB 3.59Å; F216-W276 AromaticContact CE1-CD1 3.92Å; F216-W276 AromaticContact CE1-CG 3.87Å; F216-W276 HydrophobicContact CE1-CG 3.87Å; F216-W276 HydrophobicContact CE2-CB 4.45Å; F216-W276 HydrophobicContact CZ-CB 3.54Å; F216-W276 HydrophobicContact CZ-CG 4.28Å; F216-M279 HydrophobicContact CB-CE 3.88Å; F216-M279 HydrophobicContact CD1-CE 3.85Å; F216-M279 HydrophobicContact CD2-CE 3.9Å; F216-M279 HydrophobicContact CE1-CE 4.41Å; F216-M279 HydrophobicContact CE2-CE 4.43Å; F216-M279 HydrophobicContact CG-CE 3.6Å
217	F	93.4	Very high	91.4	Very high	71 Å²	71	64.1 Å²	64.1	31%	0.311	37%	0.371	S	S	.	.	H	α-helix	trans	-63.7	-37.1	175.8	-80.8	-64	0	0	0	112.6	I213 V214 T221 I233	I213-F217 HydrophobicContact CG2-CD2 3.82Å; I213-F217 HydrophobicContact CG2-CE2 3.72Å; I213-F217 WeakPolarHBondContact O-CD2 3.34Å; I213-F217 PolarHBondContact O-N 3.48Å; V214-F217 PolarHBondContact O-N 3.29Å; F217-T221 HydrophobicContact CD1-CG2 4.1Å; F217-T221 PolarHBondContact O-OG1 2.89Å; F217-I233 HydrophobicContact CD1-CD1 4.36Å; F217-I233 HydrophobicContact CD2-CG2 3.91Å; F217-I233 HydrophobicContact CE1-CB 4.34Å; F217-I233 HydrophobicContact CE1-CG2 4.14Å; F217-I233 HydrophobicContact CE2-CB 4.42Å; F217-I233 HydrophobicContact CE2-CG2 3.41Å; F217-I233 VanDerWaalsContact CE2-CG2 3.41Å; F217-I233 HydrophobicContact CG-CG2 4.47Å; F217-I233 HydrophobicContact CZ-CB 4.08Å; F217-I233 HydrophobicContact CZ-CG2 3.54Å
218	V	91.3	Very high	91.1	Very high	94 Å²	94	63 Å²	63	57%	0.57	36%	0.363	S	S	*	.	H	α-helix	trans	-71.7	-43.3	-179.2	171.5	0	0	0	0	112.5	V214 L215 F216	V214-V218 HydrophobicContact CG1-CG2 4.46Å; V214-V218 VanDerWaalsContact O-CG2 3.3Å; V214-V218 WeakPolarHBondContact O-CG2 3.45Å; V214-V218 PolarHBondContact O-N 2.91Å; L215-V218 PolarHBondContact O-N 3.38Å; F216-V218 VanDerWaalsContact C-N 3.32Å; F216-V218 PolarHBondContact O-N 3.09Å
219	Y	87.8	Confident	91	Very high	94 Å²	94	58.3 Å²	58.3	37%	0.369	34%	0.339	S	S	.	.	H	α-helix	trans	-101.7	-32	-170.5	-66.3	-64.6	0	0	0	114.8	L215 P289 I294	L215-Y219 HydrophobicContact CB-CD2 4.31Å; L215-Y219 HydrophobicContact CD2-CD2 4.26Å; L215-Y219 HydrophobicContact CD2-CE2 3.71Å; L215-Y219 VanDerWaalsContact O-CD2 3.31Å; L215-Y219 WeakPolarHBondContact O-CD2 3.38Å; L215-Y219 PolarHBondContact O-N 3.47Å; Y219-P289 VanDerWaalsContact O-CG 3.26Å; Y219-P289 WeakPolarHBondContact O-CG 3.36Å; Y219-I294 HydrophobicContact CD1-CB 4.42Å; Y219-I294 HydrophobicContact CD1-CD1 4.39Å; Y219-I294 HydrophobicContact CD1-CG1 3.93Å; Y219-I294 HydrophobicContact CD1-CG2 3.8Å; Y219-I294 HydrophobicContact CD2-CG2 4.16Å; Y219-I294 HydrophobicContact CE1-CB 4.47Å; Y219-I294 HydrophobicContact CE1-CG1 4.46Å; Y219-I294 HydrophobicContact CE1-CG2 3.55Å; Y219-I294 HydrophobicContact CE2-CG2 3.93Å; Y219-I294 HydrophobicContact CG-CD1 4.14Å; Y219-I294 HydrophobicContact CG-CG1 4.19Å; Y219-I294 HydrophobicContact CG-CG2 4.1Å
220	Y	88.4	Confident	90.8	Very high	10 Å²	10	61.2 Å²	61.2	4%	0.039	35%	0.351	C	S	.	.	S	Bend	trans	-102.9	2.8	-174.5	-69.9	-93	0	0	0	113.2	F216 N229 W276 M279 T280 C287	F216-Y220 HydrophobicContact CD1-CD2 4.48Å; F216-Y220 WeakPolarHBondContact O-CA 3.33Å; F216-Y220 WeakPolarHBondContact O-CB 3.37Å; F216-Y220 PolarHBondContact O-N 2.92Å; Y220-N229 WeakPolarHBondContact O-CB 3.28Å; Y220-N229 PolarHBondContact O-ND2 3.3Å; Y220-W276 AromaticContact CE2-CD1 3.84Å; Y220-W276 AromaticContact CZ-CD1 3.75Å; Y220-W276 AromaticContact CZ-NE1 3.74Å; Y220-W276 PolarHBondContact OH-NE1 2.87Å; Y220-M279 HydrophobicContact CD1-CB 3.68Å; Y220-M279 HydrophobicContact CD2-CE 4.38Å; Y220-M279 HydrophobicContact CE1-CB 4.08Å; Y220-M279 HydrophobicContact CG-CB 4.28Å; Y220-M279 HydrophobicContact CG-CE 4.21Å; Y220-M279 HydrophobicContact CG-SD 4.34Å; Y220-T280 PolarHBondContact OH-OG1 3.35Å; Y220-C287 WeakPolarHBondContact CD1-O 3.27Å
221	T	89.6	Confident	90.7	Very high	20 Å²	20	58.1 Å²	58.1	12%	0.123	34%	0.341	C	S	.	.			trans	-129.9	143.2	177.4	85.5	0	0	0	0	112	F217 N229 K230 I233	F217-T221 HydrophobicContact CD1-CG2 4.1Å; F217-T221 PolarHBondContact O-OG1 2.89Å; T221-N229 HydrophobicContact CG2-CB 4.22Å; T221-K230 HydrophobicContact CG2-CG 3.7Å; T221-I233 HydrophobicContact CG2-CD1 3.63Å
222	H	86.2	Confident	90.7	Very high	89 Å²	89	55 Å²	55	41%	0.412	32%	0.322	S	S	.	.	B	Isolated β-bridge	trans	-120.5	148.1	174.5	-81.6	-66.5	0	0	0	110.2	A224 S225 K230 N286	H222-A224 VanDerWaalsContact C-N 3.29Å; H222-A224 PolarHBondContact O-N 2.95Å; H222-S225 VanDerWaalsContact CB-OG 3.27Å; H222-S225 WeakPolarHBondContact CB-OG 3.49Å; H222-S225 PolarHBondContact O-N 2.77Å; H222-K230 WeakPolarHBondContact O-CE 3.41Å; H222-K230 PolarHBondContact O-NZ 3.46Å; H222-N286 PolarHBondContact CD2-O 3.21Å; H222-N286 PolarHBondContact NE2-O 2.64Å
223	P	82.1	Confident	90.7	Very high	126 Å²	126	54.3 Å²	54.3	82%	0.818	32%	0.315	S	S	*	.	T	Hydrogen-bonded Turn	trans	-53.4	-42.1	-178.1	-29.4	35.9	0	0	0	114.2	K230	P223-K230 PolarHBondContact O-NZ 3.4Å
224	A	82.7	Confident	90.7	Very high	106 Å²	106	55.9 Å²	55.9	88%	0.876	33%	0.329	S	S	*	.	T	Hydrogen-bonded Turn	trans	-100.1	-6.3	-175.7	0	0	0	0	0	115.5	H222	H222-A224 VanDerWaalsContact C-N 3.29Å; H222-A224 PolarHBondContact O-N 2.95Å
225	S	84.2	Confident	90.8	Very high	56 Å²	56	55 Å²	55	39%	0.392	32%	0.323	S	S	.	.	B	Isolated β-bridge	trans	-142.6	-177	-175.1	56.6	0	0	0	0	111.8	H222 S227	H222-S225 VanDerWaalsContact CB-OG 3.27Å; H222-S225 WeakPolarHBondContact CB-OG 3.49Å; H222-S225 PolarHBondContact O-N 2.77Å; S225-S227 PolarHBondContact O-N 3.07Å
226	C	87.1	Confident	90.9	Very high	10 Å²	10	51.2 Å²	51.2	7%	0.068	30%	0.303	C	S	.	.			trans	59.6	43.3	179	-40.9	0	0	0	0	113.4	E228 N229 K230 C287	C226-E228 PolarHBondContact O-N 2.87Å; C226-N229 HydrophobicContact CB-CB 4.5Å; C226-N229 PolarHBondContact O-N 3.44Å; C226-K230 PolarHBondContact O-N 2.7Å; C226-C287 WeakPolarHBondContact CA-SG 3.46Å; C226-C287 HydrophobicContact CB-CB 3.72Å; C226-C287 WeakPolarHBondContact CB-SG 3.39Å; C226-C287 WeakPolarHBondContact SG-CA 3.39Å; C226-C287 WeakPolarHBondContact SG-CB 3.45Å; C226-C287 CovalentContact SG-SG 2.03Å; C226-C287 PolarHBondContact SG-SG 2.87Å
227	S	90.9	Very high	91	Very high	79 Å²	79	54.5 Å²	54.5	55%	0.552	32%	0.32	S	S	*	.	H	α-helix	trans	-60.6	-34.7	179.2	49.2	0	0	0	0	112.6	S225 K230 A231	S225-S227 PolarHBondContact O-N 3.07Å; S227-K230 WeakPolarHBondContact O-CB 3.27Å; S227-K230 PolarHBondContact O-N 3.36Å; S227-A231 PolarHBondContact O-N 3.4Å
228	E	90.8	Very high	91.2	Very high	80 Å²	80	57.1 Å²	57.1	37%	0.374	34%	0.336	S	S	.	.	H	α-helix	trans	-64.3	-47.8	179	-59.5	-56.3	155.1	0	0	111.6	C226 K230 A231 F232 W420	C226-E228 PolarHBondContact O-N 2.87Å; E228-K230 VanDerWaalsContact C-N 3.32Å; E228-K230 PolarHBondContact O-N 3.37Å; E228-A231 WeakPolarHBondContact O-CA 3.32Å; E228-A231 WeakPolarHBondContact O-CB 3.38Å; E228-A231 PolarHBondContact O-N 3.21Å; E228-F232 HydrophobicContact CB-CE2 4.05Å; E228-F232 HydrophobicContact CB-CZ 4.23Å; E228-F232 WeakPolarHBondContact O-CD2 3.39Å; E228-F232 VanDerWaalsContact O-CG 3.28Å; E228-F232 WeakPolarHBondContact O-CG 3.28Å; E228-F232 PolarHBondContact O-N 2.81Å; E228-W420 HydrophobicContact CB-CH2 3.84Å; E228-W420 HydrophobicContact CB-CZ3 4.13Å; E228-W420 HydrophobicContact CG-CH2 3.75Å; E228-W420 HydrophobicContact CG-CZ3 4.21Å
229	N	92.6	Very high	91.4	Very high	0 Å²	0	55.9 Å²	55.9	0%	0	33%	0.326	C	S	.	.	H	α-helix	trans	-60.4	-41.5	175.4	-71.2	-8.6	0	0	0	112.1	Y220 T221 C226 A231 F232 I233 M279 E282 C287	Y220-N229 WeakPolarHBondContact O-CB 3.28Å; Y220-N229 PolarHBondContact O-ND2 3.3Å; T221-N229 HydrophobicContact CG2-CB 4.22Å; C226-N229 HydrophobicContact CB-CB 4.5Å; C226-N229 PolarHBondContact O-N 3.44Å; N229-A231 VanDerWaalsContact C-N 3.28Å; N229-A231 PolarHBondContact O-N 3.29Å; N229-F232 PolarHBondContact O-N 3.04Å; N229-I233 WeakPolarHBondContact O-CD1 2.64Å; N229-I233 WeakPolarHBondContact O-CG1 3.07Å; N229-I233 PolarHBondContact O-N 3.09Å; N229-M279 HydrophobicContact CB-CG 4.42Å; N229-M279 HydrophobicContact CB-SD 4Å; N229-M279 WeakPolarHBondContact OD1-CG 3.41Å; N229-E282 PolarHBondContact ND2-OE2 3.44Å; N229-E282 PolarHBondContact OD1-OE2 3.45Å; N229-C287 PolarHBondContact ND2-O 3.41Å
230	K	93.5	Very high	91.8	Very high	63 Å²	63	51.7 Å²	51.7	27%	0.274	31%	0.311	S	S	.	.	H	α-helix	trans	-58.1	-43.3	174	-67.9	177.9	-172.1	172.2	0	111.3	T221 H222 P223 C226 S227 E228 S234	T221-K230 HydrophobicContact CG2-CG 3.7Å; H222-K230 WeakPolarHBondContact O-CE 3.41Å; H222-K230 PolarHBondContact O-NZ 3.46Å; P223-K230 PolarHBondContact O-NZ 3.4Å; C226-K230 PolarHBondContact O-N 2.7Å; S227-K230 WeakPolarHBondContact O-CB 3.27Å; S227-K230 PolarHBondContact O-N 3.36Å; E228-K230 VanDerWaalsContact C-N 3.32Å; E228-K230 PolarHBondContact O-N 3.37Å; K230-S234 VanDerWaalsContact O-CB 3.25Å; K230-S234 WeakPolarHBondContact O-CB 3.26Å; K230-S234 PolarHBondContact O-N 3.06Å; K230-S234 PolarHBondContact O-OG 3.06Å
231	A	94.5	Very high	92.2	Very high	42 Å²	42	54.9 Å²	54.9	35%	0.347	33%	0.331	S	S	.	.	H	α-helix	trans	-65.2	-48.3	178.1	0	0	0	0	0	111.5	S227 E228 N229 I233 S234 V235	S227-A231 PolarHBondContact O-N 3.4Å; E228-A231 WeakPolarHBondContact O-CA 3.32Å; E228-A231 WeakPolarHBondContact O-CB 3.38Å; E228-A231 PolarHBondContact O-N 3.21Å; N229-A231 VanDerWaalsContact C-N 3.28Å; N229-A231 PolarHBondContact O-N 3.29Å; A231-I233 PolarHBondContact O-N 3.33Å; A231-S234 PolarHBondContact O-N 3.37Å; A231-V235 WeakPolarHBondContact O-CB 3.22Å; A231-V235 VanDerWaalsContact O-CG2 3.28Å; A231-V235 WeakPolarHBondContact O-CG2 3.25Å; A231-V235 PolarHBondContact O-N 2.97Å
232	F	95.2	Very high	92.4	Very high	5 Å²	5	55.3 Å²	55.3	2%	0.022	34%	0.339	C	S	.	.	H	α-helix	trans	-58.8	-48	179.4	-61.8	-30.2	0	0	0	112.5	E228 N229 N236 W420 V423 W424 I427	E228-F232 HydrophobicContact CB-CE2 4.05Å; E228-F232 HydrophobicContact CB-CZ 4.23Å; E228-F232 WeakPolarHBondContact O-CD2 3.39Å; E228-F232 VanDerWaalsContact O-CG 3.28Å; E228-F232 WeakPolarHBondContact O-CG 3.28Å; E228-F232 PolarHBondContact O-N 2.81Å; N229-F232 PolarHBondContact O-N 3.04Å; F232-N236 WeakPolarHBondContact O-CB 3.48Å; F232-N236 PolarHBondContact O-N 2.85Å; F232-W420 HydrophobicContact CE2-CZ3 4.23Å; F232-W420 HydrophobicContact CZ-CZ3 4.38Å; F232-V423 HydrophobicContact CD2-CG1 4.46Å; F232-V423 HydrophobicContact CE2-CG1 3.7Å; F232-V423 HydrophobicContact CZ-CG1 4.22Å; F232-W424 HydrophobicContact CE1-CH2 4.08Å; F232-W424 HydrophobicContact CE1-CZ2 4.44Å; F232-W424 HydrophobicContact CE1-CZ3 4.33Å; F232-W424 HydrophobicContact CZ-CH2 4.45Å; F232-W424 HydrophobicContact CZ-CZ2 4.36Å; F232-I427 HydrophobicContact CB-CD1 3.99Å; F232-I427 HydrophobicContact CD1-CD1 4.31Å; F232-I427 HydrophobicContact CD1-CG1 4.12Å; F232-I427 HydrophobicContact CD1-CG2 3.96Å; F232-I427 HydrophobicContact CD2-CD1 4.22Å; F232-I427 HydrophobicContact CD2-CG1 4.17Å; F232-I427 HydrophobicContact CE1-CG1 4.3Å; F232-I427 HydrophobicContact CE1-CG2 4.15Å; F232-I427 HydrophobicContact CE2-CG1 4.34Å; F232-I427 HydrophobicContact CG-CD1 3.93Å; F232-I427 HydrophobicContact CG-CG1 4.07Å; F232-I427 HydrophobicContact CZ-CG1 4.41Å
233	I	96	Very high	92.8	Very high	1 Å²	1	51.3 Å²	51.3	1%	0.005	32%	0.321	C	S	.	.	H	α-helix	trans	-62.5	-47	178.8	-60.1	158.6	0	0	0	110.2	I213 F216 F217 T221 N229 A231 M237 T275 M279	I213-I233 HydrophobicContact CG2-CG2 4.18Å; F216-I233 HydrophobicContact CB-CD1 3.54Å; F216-I233 HydrophobicContact CB-CG1 3.89Å; F216-I233 HydrophobicContact CB-CG2 4.41Å; F216-I233 HydrophobicContact CD2-CG1 4.41Å; F217-I233 HydrophobicContact CD1-CD1 4.36Å; F217-I233 HydrophobicContact CD2-CG2 3.91Å; F217-I233 HydrophobicContact CE1-CB 4.34Å; F217-I233 HydrophobicContact CE1-CG2 4.14Å; F217-I233 HydrophobicContact CE2-CB 4.42Å; F217-I233 HydrophobicContact CE2-CG2 3.41Å; F217-I233 VanDerWaalsContact CE2-CG2 3.41Å; F217-I233 HydrophobicContact CG-CG2 4.47Å; F217-I233 HydrophobicContact CZ-CB 4.08Å; F217-I233 HydrophobicContact CZ-CG2 3.54Å; T221-I233 HydrophobicContact CG2-CD1 3.63Å; N229-I233 WeakPolarHBondContact O-CD1 2.64Å; N229-I233 WeakPolarHBondContact O-CG1 3.07Å; N229-I233 PolarHBondContact O-N 3.09Å; A231-I233 PolarHBondContact O-N 3.33Å; I233-M237 VanDerWaalsContact O-CB 3.22Å; I233-M237 WeakPolarHBondContact O-CB 3.33Å; I233-M237 PolarHBondContact O-N 3.02Å; I233-T275 HydrophobicContact CG1-CG2 4.36Å; I233-M279 HydrophobicContact CD1-CE 4.4Å; I233-M279 HydrophobicContact CD1-SD 3.77Å; I233-M279 HydrophobicContact CG1-CE 4.17Å; I233-M279 HydrophobicContact CG1-SD 3.67Å
234	S	95.8	Very high	93.4	Very high	56 Å²	56	46 Å²	46	39%	0.392	29%	0.288	S	S	.	.	H	α-helix	trans	-66.3	-43.5	-176.1	-56.6	0	0	0	0	112.5	K230 A231 L238	K230-S234 VanDerWaalsContact O-CB 3.25Å; K230-S234 WeakPolarHBondContact O-CB 3.26Å; K230-S234 PolarHBondContact O-N 3.06Å; K230-S234 PolarHBondContact O-OG 3.06Å; A231-S234 PolarHBondContact O-N 3.37Å; S234-L238 WeakPolarHBondContact O-CB 3.45Å; S234-L238 PolarHBondContact O-N 2.96Å
235	V	96.6	Very high	94	Very high	61 Å²	61	44.6 Å²	44.6	37%	0.37	27%	0.268	S	S	.	.	H	α-helix	trans	-65.2	-48.6	178.1	171.2	0	0	0	0	110.2	A231 M237 L238 L239 W431	A231-V235 WeakPolarHBondContact O-CB 3.22Å; A231-V235 VanDerWaalsContact O-CG2 3.28Å; A231-V235 WeakPolarHBondContact O-CG2 3.25Å; A231-V235 PolarHBondContact O-N 2.97Å; V235-M237 VanDerWaalsContact C-N 3.33Å; V235-M237 PolarHBondContact O-N 2.88Å; V235-L238 PolarHBondContact O-N 2.87Å; V235-L239 HydrophobicContact CG1-CD1 3.8Å; V235-L239 HydrophobicContact CG1-CG 4.23Å; V235-L239 WeakPolarHBondContact O-CB 3.32Å; V235-L239 VanDerWaalsContact O-CG 3.27Å; V235-L239 WeakPolarHBondContact O-CG 3.29Å; V235-L239 PolarHBondContact O-N 3.42Å; V235-W431 HydrophobicContact CG1-CZ2 4.23Å
236	N	96.7	Very high	94.3	Very high	0 Å²	0	44.4 Å²	44.4	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-65	-37.7	-179.6	-76.9	-3	0	0	0	112.3	F232 C240 T271 M272 T275 S430 W431	F232-N236 WeakPolarHBondContact O-CB 3.48Å; F232-N236 PolarHBondContact O-N 2.85Å; N236-C240 WeakPolarHBondContact O-CB 3.33Å; N236-C240 PolarHBondContact O-N 3.3Å; N236-C240 PolarHBondContact O-SG 2.97Å; N236-T271 HydrophobicContact CB-CG2 3.94Å; N236-M272 HydrophobicContact CB-CE 4.16Å; N236-T275 PolarHBondContact ND2-OG1 3.11Å; N236-S430 PolarHBondContact ND2-OG 2.63Å; N236-W431 PolarHBondContact OD1-NE1 3.37Å
237	M	95.8	Very high	94.5	Very high	82 Å²	82	44 Å²	44	40%	0.404	26%	0.258	S	S	.	.	H	α-helix	trans	-58.5	-51.2	171.6	174.6	-175	157.5	0	0	111.2	I213 I233 V235 L239 C240 V241	I213-M237 HydrophobicContact CD1-CB 4.3Å; I213-M237 HydrophobicContact CD1-CG 4.14Å; I213-M237 HydrophobicContact CG2-SD 4.32Å; I233-M237 VanDerWaalsContact O-CB 3.22Å; I233-M237 WeakPolarHBondContact O-CB 3.33Å; I233-M237 PolarHBondContact O-N 3.02Å; V235-M237 VanDerWaalsContact C-N 3.33Å; V235-M237 PolarHBondContact O-N 2.88Å; M237-L239 PolarHBondContact O-N 2.91Å; M237-C240 PolarHBondContact O-N 3.07Å; M237-V241 WeakPolarHBondContact O-CG2 3.5Å; M237-V241 PolarHBondContact O-N 2.67Å
238	L	96.5	Very high	94.5	Very high	126 Å²	126	44.5 Å²	44.5	66%	0.66	25%	0.254	S	S	*	.	H	α-helix	trans	-62.2	-42.9	-179	-178.5	61.7	0	0	0	111.9	S234 V235 V241 G242	S234-L238 WeakPolarHBondContact O-CB 3.45Å; S234-L238 PolarHBondContact O-N 2.96Å; V235-L238 PolarHBondContact O-N 2.87Å; L238-V241 PolarHBondContact O-N 3.4Å; L238-G242 PolarHBondContact O-N 3.12Å
239	L	96.3	Very high	94.5	Very high	67 Å²	67	44.4 Å²	44.4	35%	0.351	26%	0.256	S	S	.	.	H	α-helix	trans	-62.4	-42.2	176.8	-70.3	175.9	0	0	0	111.9	V235 M237 G242 A243 W431 I434	V235-L239 HydrophobicContact CG1-CD1 3.8Å; V235-L239 HydrophobicContact CG1-CG 4.23Å; V235-L239 WeakPolarHBondContact O-CB 3.32Å; V235-L239 VanDerWaalsContact O-CG 3.27Å; V235-L239 WeakPolarHBondContact O-CG 3.29Å; V235-L239 PolarHBondContact O-N 3.42Å; M237-L239 PolarHBondContact O-N 2.91Å; L239-G242 PolarHBondContact O-N 3.29Å; L239-A243 WeakPolarHBondContact O-CB 3.29Å; L239-A243 PolarHBondContact O-N 3.04Å; L239-W431 HydrophobicContact CD1-CG 4.34Å; L239-I434 HydrophobicContact CB-CD1 3.58Å; L239-I434 HydrophobicContact CB-CG2 4.23Å; L239-I434 HydrophobicContact CD1-CD1 4.06Å; L239-I434 HydrophobicContact CG-CD1 4.48Å
240	C	96.4	Very high	94.3	Very high	7 Å²	7	48.5 Å²	48.5	5%	0.047	28%	0.282	C	S	.	.	H	α-helix	trans	-67.3	-39.1	177.3	-68.3	0	0	0	0	112.7	N236 M237 A243 S244 T268	N236-C240 WeakPolarHBondContact O-CB 3.33Å; N236-C240 PolarHBondContact O-N 3.3Å; N236-C240 PolarHBondContact O-SG 2.97Å; M237-C240 PolarHBondContact O-N 3.07Å; C240-A243 PolarHBondContact O-N 3.46Å; C240-S244 WeakPolarHBondContact O-CB 3.3Å; C240-S244 PolarHBondContact O-N 2.89Å; C240-S244 PolarHBondContact O-OG 3.24Å; C240-T268 HydrophobicContact CB-CG2 3.75Å
241	V	95.7	Very high	94	Very high	77 Å²	77	51.8 Å²	51.8	47%	0.467	30%	0.296	S	S	.	.	H	α-helix	trans	-62.8	-47.3	173.6	171.4	0	0	0	0	110	M237 L238 A243 S244 V245	M237-V241 WeakPolarHBondContact O-CG2 3.5Å; M237-V241 PolarHBondContact O-N 2.67Å; L238-V241 PolarHBondContact O-N 3.4Å; V241-A243 PolarHBondContact O-N 3.01Å; V241-S244 PolarHBondContact O-N 3.05Å; V241-V245 HydrophobicContact CG1-CG2 4.46Å; V241-V245 WeakPolarHBondContact O-CG2 3.47Å; V241-V245 PolarHBondContact O-N 3.33Å
242	G	95.3	Very high	93.7	Very high	29 Å²	29	50 Å²	50	30%	0.299	28%	0.281	S	S	.	.	H	α-helix	trans	-58	-46.6	175.9	0	0	0	0	0	112.7	L238 L239 S244 V245 M246	L238-G242 PolarHBondContact O-N 3.12Å; L239-G242 PolarHBondContact O-N 3.29Å; G242-S244 VanDerWaalsContact C-N 3.33Å; G242-S244 PolarHBondContact O-N 2.94Å; G242-V245 PolarHBondContact O-N 2.75Å; G242-M246 WeakPolarHBondContact O-CE 3.49Å; G242-M246 WeakPolarHBondContact O-CG 3.19Å; G242-M246 PolarHBondContact O-N 3.16Å
243	A	94.5	Very high	93.2	Very high	4 Å²	4	53.6 Å²	53.6	3%	0.033	30%	0.298	C	S	.	.	H	α-helix	trans	-61	-39.3	176.4	0	0	0	0	0	112.8	L239 C240 V241 S247 I434 Y437 V438	L239-A243 WeakPolarHBondContact O-CB 3.29Å; L239-A243 PolarHBondContact O-N 3.04Å; C240-A243 PolarHBondContact O-N 3.46Å; V241-A243 PolarHBondContact O-N 3.01Å; A243-S247 PolarHBondContact O-N 3.19Å; A243-S247 VanDerWaalsContact O-N 3.08Å; A243-S247 PolarHBondContact O-OG 2.79Å; A243-I434 HydrophobicContact CB-CG2 4.23Å; A243-Y437 HydrophobicContact CB-CD1 4.12Å; A243-Y437 HydrophobicContact CB-CE1 4.15Å; A243-V438 HydrophobicContact CB-CG2 4Å
244	S	94.7	Very high	92.7	Very high	16 Å²	16	59.9 Å²	59.9	11%	0.112	33%	0.327	C	S	.	.	H	α-helix	trans	-67.9	-42.3	176.5	-58.7	0	0	0	0	111.9	Y206 C240 V241 G242 S247	Y206-S244 WeakPolarHBondContact OH-CB 3.37Å; Y206-S244 PolarHBondContact OH-OG 3.33Å; C240-S244 WeakPolarHBondContact O-CB 3.3Å; C240-S244 PolarHBondContact O-N 2.89Å; C240-S244 PolarHBondContact O-OG 3.24Å; V241-S244 PolarHBondContact O-N 3.05Å; G242-S244 VanDerWaalsContact C-N 3.33Å; G242-S244 PolarHBondContact O-N 2.94Å; S244-S247 WeakPolarHBondContact O-CB 3.2Å; S244-S247 PolarHBondContact O-N 3.41Å
245	V	93.9	Very high	92	Very high	75 Å²	75	59.1 Å²	59.1	46%	0.455	32%	0.322	S	S	.	.	H	α-helix	trans	-62.7	-44.5	175.1	171.9	0	0	0	0	110.8	V241 G242 S247 I248 L249	V241-V245 HydrophobicContact CG1-CG2 4.46Å; V241-V245 WeakPolarHBondContact O-CG2 3.47Å; V241-V245 PolarHBondContact O-N 3.33Å; G242-V245 PolarHBondContact O-N 2.75Å; V245-S247 VanDerWaalsContact C-N 3.27Å; V245-S247 PolarHBondContact O-N 3.28Å; V245-I248 WeakPolarHBondContact O-CG1 3.18Å; V245-I248 PolarHBondContact O-N 2.82Å; V245-L249 PolarHBondContact O-N 3.17Å
246	M	92	Very high	91.2	Very high	53 Å²	53	58.4 Å²	58.4	26%	0.261	32%	0.315	S	S	.	.	H	α-helix	trans	-60.8	-37.6	176.6	-73.6	-176	-69.6	0	0	112.1	G242 I248 L249 I252 V438	G242-M246 WeakPolarHBondContact O-CE 3.49Å; G242-M246 WeakPolarHBondContact O-CG 3.19Å; G242-M246 PolarHBondContact O-N 3.16Å; M246-I248 PolarHBondContact O-N 3.07Å; M246-I248 VanDerWaalsContact O-N 3.11Å; M246-L249 HydrophobicContact CG-CD1 4.25Å; M246-L249 PolarHBondContact O-N 2.65Å; M246-L249 VanDerWaalsContact O-N 3.16Å; M246-I252 HydrophobicContact CB-CD1 4.02Å; M246-I252 WeakPolarHBondContact O-CD1 3.37Å; M246-V438 HydrophobicContact CE-CB 4.05Å; M246-V438 HydrophobicContact CE-CG1 3.44Å; M246-V438 VanDerWaalsContact CE-CG1 3.44Å; M246-V438 HydrophobicContact CE-CG2 3.36Å; M246-V438 HydrophobicContact SD-CG1 3.75Å
247	S	90.7	Very high	90.2	Very high	0 Å²	0	63.8 Å²	63.8	0%	0	35%	0.35	C	S	.	.	H	α-helix	trans	-63	-18.8	179.6	-54.1	0	0	0	0	114.1	A243 S244 V245 S264 Y437 L441	A243-S247 PolarHBondContact O-N 3.19Å; A243-S247 VanDerWaalsContact O-N 3.08Å; A243-S247 PolarHBondContact O-OG 2.79Å; S244-S247 WeakPolarHBondContact O-CB 3.2Å; S244-S247 PolarHBondContact O-N 3.41Å; V245-S247 VanDerWaalsContact C-N 3.27Å; V245-S247 PolarHBondContact O-N 3.28Å; S247-S264 WeakPolarHBondContact OG-CB 3.22Å; S247-Y437 PolarHBondContact OG-OH 3.22Å; S247-L441 WeakPolarHBondContact OG-CD1 3.47Å
248	I	91.1	Very high	89.4	Confident	91 Å²	91	64.9 Å²	64.9	47%	0.467	35%	0.349	S	S	.	.	T	Hydrogen-bonded Turn	trans	-108.7	1.7	179.7	63.7	166	0	0	0	113.6	V245 M246 L261	V245-I248 WeakPolarHBondContact O-CG1 3.18Å; V245-I248 PolarHBondContact O-N 2.82Å; M246-I248 PolarHBondContact O-N 3.07Å; M246-I248 VanDerWaalsContact O-N 3.11Å; I248-L261 HydrophobicContact CG2-CD1 3.87Å
249	L	91.2	Very high	88.5	Confident	77 Å²	77	59.2 Å²	59.2	40%	0.403	32%	0.321	S	S	.	.			trans	-66.9	130.2	179.1	-74.1	174.1	0	0	0	109.7	V245 M246 K251 I252 Q253	V245-L249 PolarHBondContact O-N 3.17Å; M246-L249 HydrophobicContact CG-CD1 4.25Å; M246-L249 PolarHBondContact O-N 2.65Å; M246-L249 VanDerWaalsContact O-N 3.16Å; L249-K251 PolarHBondContact O-N 3.48Å; L249-K251 VanDerWaalsContact O-N 3.11Å; L249-I252 HydrophobicContact CB-CD1 4.35Å; L249-I252 HydrophobicContact CD1-CD1 4.38Å; L249-I252 PolarHBondContact O-N 3.32Å; L249-Q253 PolarHBondContact O-N 3.35Å; L249-Q253 VanDerWaalsContact O-N 3.13Å
250	P	87.7	Confident	87.8	Confident	86 Å²	86	56.6 Å²	56.6	56%	0.558	31%	0.31	S	S	*	.	H	α-helix	trans	-54.6	-36.9	-177.9	-28.2	34.5	0	0	0	113.2	I252 Q253 E254	P250-I252 VanDerWaalsContact C-N 3.33Å; P250-I252 PolarHBondContact O-N 3.28Å; P250-Q253 PolarHBondContact O-N 2.91Å; P250-E254 WeakPolarHBondContact O-CB 3.29Å; P250-E254 VanDerWaalsContact O-CG 3.28Å; P250-E254 WeakPolarHBondContact O-CG 3.36Å; P250-E254 PolarHBondContact O-N 2.9Å
251	K	87.9	Confident	87.7	Confident	132 Å²	132	59.5 Å²	59.5	57%	0.574	32%	0.324	S	S	*	.	H	α-helix	trans	-60.3	-39.7	177.2	-73.5	-74.9	153.5	-144.1	0	113.1	L249 E254 S255 L445	L249-K251 PolarHBondContact O-N 3.48Å; L249-K251 VanDerWaalsContact O-N 3.11Å; K251-E254 IonicContact NZ-OE1 3.71Å; K251-E254 IonicContact NZ-OE2 2.77Å; K251-E254 PolarHBondContact NZ-OE2 3.44Å; K251-S255 PolarHBondContact O-N 3.29Å; K251-L445 WeakPolarHBondContact O-CD2 3.34Å
252	I	87	Confident	87.5	Confident	6 Å²	6	55.9 Å²	55.9	3%	0.031	30%	0.302	C	S	.	.	H	α-helix	trans	-72.7	-43.1	178	-72.6	168.6	0	0	0	109.7	M246 L249 P250 E254 S255 Q256 L441 V442 L445	M246-I252 HydrophobicContact CB-CD1 4.02Å; M246-I252 WeakPolarHBondContact O-CD1 3.37Å; L249-I252 HydrophobicContact CB-CD1 4.35Å; L249-I252 HydrophobicContact CD1-CD1 4.38Å; L249-I252 PolarHBondContact O-N 3.32Å; P250-I252 VanDerWaalsContact C-N 3.33Å; P250-I252 PolarHBondContact O-N 3.28Å; I252-E254 VanDerWaalsContact C-N 3.3Å; I252-E254 PolarHBondContact O-N 2.98Å; I252-S255 PolarHBondContact O-N 3.27Å; I252-S255 VanDerWaalsContact O-N 3.08Å; I252-S255 PolarHBondContact O-OG 2.98Å; I252-Q256 PolarHBondContact O-N 3.48Å; I252-L441 HydrophobicContact CD1-CB 4.47Å; I252-L441 HydrophobicContact CG2-CB 4.13Å; I252-L441 HydrophobicContact CG2-CD2 4.43Å; I252-V442 HydrophobicContact CD1-CG2 4.41Å; I252-L445 HydrophobicContact CG1-CD1 3.59Å
253	Q	86.6	Confident	87.4	Confident	80 Å²	80	54.5 Å²	54.5	37%	0.374	29%	0.288	S	S	.	.	H	α-helix	trans	-65.2	-31.4	178	-68.1	-176	-19.2	0	0	113.2	L249 P250 S255 Q256 P257	L249-Q253 PolarHBondContact O-N 3.35Å; L249-Q253 VanDerWaalsContact O-N 3.13Å; P250-Q253 PolarHBondContact O-N 2.91Å; Q253-S255 VanDerWaalsContact C-N 3.32Å; Q253-Q256 CarbonylContact O-C 3.24Å; Q253-Q256 VanDerWaalsContact O-C 3.24Å; Q253-P257 VanDerWaalsContact O-CA 3.32Å; Q253-P257 WeakPolarHBondContact O-CA 3.34Å
254	E	84.7	Confident	87.5	Confident	132 Å²	132	54.4 Å²	54.4	62%	0.617	29%	0.287	S	S	*	.	H	α-helix	trans	-61.2	-40.2	170.9	-77.9	167.5	-166.4	0	0	111.5	P250 K251 I252	P250-E254 WeakPolarHBondContact O-CB 3.29Å; P250-E254 VanDerWaalsContact O-CG 3.28Å; P250-E254 WeakPolarHBondContact O-CG 3.36Å; P250-E254 PolarHBondContact O-N 2.9Å; K251-E254 IonicContact NZ-OE1 3.71Å; K251-E254 IonicContact NZ-OE2 2.77Å; K251-E254 PolarHBondContact NZ-OE2 3.44Å; I252-E254 VanDerWaalsContact C-N 3.3Å; I252-E254 PolarHBondContact O-N 2.98Å
255	S	81.6	Confident	87.5	Confident	41 Å²	41	53.6 Å²	53.6	29%	0.287	28%	0.282	S	S	.	.	H	α-helix	trans	-84.1	-26.4	179.2	64.5	0	0	0	0	114.4	K251 I252 Q253 L445	K251-S255 PolarHBondContact O-N 3.29Å; I252-S255 PolarHBondContact O-N 3.27Å; I252-S255 VanDerWaalsContact O-N 3.08Å; I252-S255 PolarHBondContact O-OG 2.98Å; Q253-S255 VanDerWaalsContact C-N 3.32Å; S255-L445 WeakPolarHBondContact OG-CD2 3.34Å
256	Q	79	Confident	87.6	Confident	46 Å²	46	50.8 Å²	50.8	22%	0.215	27%	0.265	C	S	.	.			trans	-137.4	88	177.4	-74.7	-150.9	-20.9	0	0	109.4	I252 Q253 R258 S259 P444	I252-Q256 PolarHBondContact O-N 3.48Å; Q253-Q256 CarbonylContact O-C 3.24Å; Q253-Q256 VanDerWaalsContact O-C 3.24Å; Q256-R258 PolarHBondContact O-N 3.44Å; Q256-R258 VanDerWaalsContact O-N 3.12Å; Q256-S259 WeakPolarHBondContact CB-OG 3.5Å; Q256-S259 VanDerWaalsContact O-CB 3.26Å; Q256-S259 WeakPolarHBondContact O-CB 3.45Å; Q256-S259 PolarHBondContact O-N 3.38Å; Q256-S259 PolarHBondContact OE1-OG 3.37Å; Q256-P444 HydrophobicContact CG-CB 4.36Å; Q256-P444 HydrophobicContact CG-CG 3.88Å
257	P	76.3	Confident	87.8	Confident	113 Å²	113	48.5 Å²	48.5	73%	0.734	25%	0.253	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.2	-23	-177.8	23.9	-33.7	0	0	0	112.6	Q253 S259	Q253-P257 VanDerWaalsContact O-CA 3.32Å; Q253-P257 WeakPolarHBondContact O-CA 3.34Å; P257-S259 VanDerWaalsContact C-N 3.32Å
258	R	77.7	Confident	88	Confident	104 Å²	104	48.9 Å²	48.9	39%	0.392	26%	0.256	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.1	3.4	175.2	-58.1	-169.5	177.1	-173.4	-10.5	113.8	N179 E180 Q256 Q263	N179-R258 PolarHBondContact ND2-O 3.3Å; E180-R258 HydrophobicContact CG-CB 4.09Å; Q256-R258 PolarHBondContact O-N 3.44Å; Q256-R258 VanDerWaalsContact O-N 3.12Å; R258-Q263 PolarHBondContact O-NE2 3.29Å
259	S	77.7	Confident	88.3	Confident	8 Å²	8	46 Å²	46	6%	0.056	24%	0.243	C	C	.	.			trans	-71.1	131	169.9	-80.6	0	0	0	0	110.5	Q256 P257 L441	Q256-S259 WeakPolarHBondContact CB-OG 3.5Å; Q256-S259 VanDerWaalsContact O-CB 3.26Å; Q256-S259 WeakPolarHBondContact O-CB 3.45Å; Q256-S259 PolarHBondContact O-N 3.38Å; Q256-S259 PolarHBondContact OE1-OG 3.37Å; P257-S259 VanDerWaalsContact C-N 3.32Å; S259-L441 WeakPolarHBondContact OG-CD2 3.33Å
260	G	83.1	Confident	88.4	Confident	12 Å²	12	42.9 Å²	42.9	12%	0.124	23%	0.225	C	C	.	.			trans	-141.8	175.7	-174.9	0	0	0	0	0	113.1	L262 Q263	G260-L262 VanDerWaalsContact C-N 3.32Å; G260-Q263 PolarHBondContact O-OE1 3.13Å
261	L	92.7	Very high	88.8	Confident	68 Å²	68	38.8 Å²	38.8	36%	0.356	20%	0.199	S	C	.	.	H	α-helix	trans	-80.6	-18.1	178	-162.3	74.4	0	0	0	111.8	T202 Y206 I248 S264 S265	T202-L261 HydrophobicContact CG2-CB 3.94Å; T202-L261 HydrophobicContact CG2-CD2 3.66Å; T202-L261 HydrophobicContact CG2-CG 3.77Å; Y206-L261 HydrophobicContact CD2-CD2 4.46Å; Y206-L261 HydrophobicContact CE2-CD1 4.13Å; Y206-L261 HydrophobicContact CE2-CD2 3.66Å; Y206-L261 HydrophobicContact CE2-CG 3.61Å; Y206-L261 VanDerWaalsContact OH-CD1 3.26Å; Y206-L261 WeakPolarHBondContact OH-CD1 3.38Å; I248-L261 HydrophobicContact CG2-CD1 3.87Å; L261-S264 PolarHBondContact O-OG 2.92Å; L261-S265 WeakPolarHBondContact O-CB 3.47Å; L261-S265 PolarHBondContact O-N 2.9Å
262	L	93.1	Very high	89.2	Confident	1 Å²	1	32.8 Å²	32.8	1%	0.005	17%	0.173	C	C	.	.	H	α-helix	trans	-61.4	-47.5	176.2	-175.4	72.9	0	0	0	110.5	W178 N179 L198 A201 G260 S264 S265 V266	W178-L262 HydrophobicContact CB-CD2 4.47Å; W178-L262 HydrophobicContact CD2-CD2 4.18Å; W178-L262 HydrophobicContact CG-CD2 3.97Å; N179-L262 HydrophobicContact CB-CB 4.48Å; N179-L262 HydrophobicContact CB-CD2 4.11Å; L198-L262 HydrophobicContact CD1-CB 3.96Å; L198-L262 HydrophobicContact CD1-CD1 4.49Å; L198-L262 HydrophobicContact CD1-CD2 3.76Å; L198-L262 HydrophobicContact CD1-CG 4.27Å; A201-L262 HydrophobicContact CB-CD1 3.76Å; G260-L262 VanDerWaalsContact C-N 3.32Å; L262-S264 PolarHBondContact O-N 3.26Å; L262-S265 PolarHBondContact O-N 2.73Å; L262-S265 PolarHBondContact O-OG 2.89Å; L262-V266 WeakPolarHBondContact O-CG2 3.5Å; L262-V266 PolarHBondContact O-N 3.38Å; L262-V266 VanDerWaalsContact O-N 3.08Å
263	Q	93.1	Very high	89.5	Confident	0 Å²	0	33.7 Å²	33.7	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-58.8	-51.5	-178.4	-60.2	97.1	-39.3	0	0	111.3	A175 N179 R258 G260 S265 V266 I267 Y437	A175-Q263 HydrophobicContact CB-CB 4.33Å; A175-Q263 HydrophobicContact CB-CG 4.39Å; N179-Q263 VanDerWaalsContact CB-CD 3.44Å; N179-Q263 HydrophobicContact CB-CG 4.01Å; N179-Q263 PolarHBondContact ND2-NE2 2.94Å; N179-Q263 VanDerWaalsContact ND2-NE2 3.16Å; R258-Q263 PolarHBondContact O-NE2 3.29Å; G260-Q263 PolarHBondContact O-OE1 3.13Å; Q263-S265 VanDerWaalsContact C-N 3.3Å; Q263-S265 PolarHBondContact O-N 3.27Å; Q263-V266 PolarHBondContact O-N 3.48Å; Q263-I267 WeakPolarHBondContact O-CG1 3.38Å; Q263-I267 PolarHBondContact O-N 2.83Å; Q263-I267 VanDerWaalsContact O-N 3.1Å; Q263-Y437 HydrophobicContact CB-CE2 3.82Å
264	S	94.8	Very high	89.9	Confident	1 Å²	1	30.1 Å²	30.1	1%	0.007	16%	0.159	C	C	.	.	H	α-helix	trans	-63.3	-34.3	179	46.3	0	0	0	0	112.8	Y206 S247 L261 L262 I267 T268 Y437	Y206-S264 PolarHBondContact OH-OG 3.1Å; Y206-S264 VanDerWaalsContact OH-OG 3.13Å; S247-S264 WeakPolarHBondContact OG-CB 3.22Å; L261-S264 PolarHBondContact O-OG 2.92Å; L262-S264 PolarHBondContact O-N 3.26Å; S264-I267 PolarHBondContact O-N 3.38Å; S264-T268 WeakPolarHBondContact O-CB 3.27Å; S264-T268 PolarHBondContact O-N 2.85Å; S264-T268 PolarHBondContact O-OG1 3.28Å; S264-Y437 WeakPolarHBondContact CA-OH 3.32Å; S264-Y437 WeakPolarHBondContact CB-OH 3.26Å; S264-Y437 PolarHBondContact N-OH 3.16Å; S264-Y437 VanDerWaalsContact N-OH 3.15Å
265	S	96.4	Very high	90.4	Very high	0 Å²	0	23.8 Å²	23.8	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-63.4	-41.1	174.8	80.6	0	0	0	0	112.8	N205 Y206 L261 L262 Q263 T268 V269	N205-S265 WeakPolarHBondContact CB-OG 3.34Å; N205-S265 PolarHBondContact ND2-OG 2.99Å; N205-S265 VanDerWaalsContact ND2-OG 3.09Å; Y206-S265 VanDerWaalsContact CE2-CB 3.47Å; L261-S265 WeakPolarHBondContact O-CB 3.47Å; L261-S265 PolarHBondContact O-N 2.9Å; L262-S265 PolarHBondContact O-N 2.73Å; L262-S265 PolarHBondContact O-OG 2.89Å; Q263-S265 VanDerWaalsContact C-N 3.3Å; Q263-S265 PolarHBondContact O-N 3.27Å; S265-T268 PolarHBondContact O-N 3Å; S265-V269 WeakPolarHBondContact O-CG2 3.2Å; S265-V269 PolarHBondContact O-N 3.27Å
266	V	95.7	Very high	90.9	Very high	16 Å²	16	23.8 Å²	23.8	10%	0.097	12%	0.124	C	C	.	.	H	α-helix	trans	-66.7	-45	177.7	172.6	0	0	0	0	110.7	L171 A175 L262 Q263 T268 V269 Y270	L171-V266 HydrophobicContact CD1-CG1 4.23Å; L171-V266 HydrophobicContact CG-CG1 4.39Å; A175-V266 HydrophobicContact CB-CB 4.16Å; A175-V266 HydrophobicContact CB-CG1 4.11Å; L262-V266 WeakPolarHBondContact O-CG2 3.5Å; L262-V266 PolarHBondContact O-N 3.38Å; L262-V266 VanDerWaalsContact O-N 3.08Å; Q263-V266 PolarHBondContact O-N 3.48Å; V266-T268 VanDerWaalsContact C-N 3.28Å; V266-T268 PolarHBondContact O-N 3.23Å; V266-V269 PolarHBondContact O-N 3.12Å; V266-Y270 PolarHBondContact O-N 3.17Å
267	I	95	Very high	91.4	Very high	4 Å²	4	21.9 Å²	21.9	2%	0.021	12%	0.116	C	C	.	.	H	α-helix	trans	-63.1	-36.7	176.6	-59.7	-52.5	0	0	0	111.4	L171 I172 Q263 S264 Y270 T271 Y437	L171-I267 HydrophobicContact CD2-CD1 4.13Å; L171-I267 HydrophobicContact CG-CD1 4.4Å; I172-I267 HydrophobicContact CB-CD1 4.44Å; I172-I267 HydrophobicContact CG1-CD1 3.53Å; I172-I267 HydrophobicContact CG1-CG1 4.38Å; Q263-I267 WeakPolarHBondContact O-CG1 3.38Å; Q263-I267 PolarHBondContact O-N 2.83Å; Q263-I267 VanDerWaalsContact O-N 3.1Å; S264-I267 PolarHBondContact O-N 3.38Å; I267-Y270 PolarHBondContact O-N 3.49Å; I267-T271 WeakPolarHBondContact O-CB 3.3Å; I267-T271 PolarHBondContact O-N 3.32Å; I267-T271 PolarHBondContact O-OG1 3.22Å; I267-Y437 HydrophobicContact CB-CG 4.5Å; I267-Y437 HydrophobicContact CG1-CD1 4.47Å; I267-Y437 HydrophobicContact CG1-CD2 3.8Å; I267-Y437 HydrophobicContact CG1-CE2 4.21Å; I267-Y437 HydrophobicContact CG1-CG 3.94Å; I267-Y437 HydrophobicContact CG2-CD1 4.44Å; I267-Y437 HydrophobicContact CG2-CG 4.32Å
268	T	96.5	Very high	92.2	Very high	8 Å²	8	16.5 Å²	16.5	5%	0.049	8%	0.081	C	C	.	.	H	α-helix	trans	-62.8	-49.5	175.8	-58.6	0	0	0	0	111.1	S209 C240 S264 S265 V266 Y270 T271 M272	S209-T268 WeakPolarHBondContact OG-CG2 3.43Å; C240-T268 HydrophobicContact CB-CG2 3.75Å; S264-T268 WeakPolarHBondContact O-CB 3.27Å; S264-T268 PolarHBondContact O-N 2.85Å; S264-T268 PolarHBondContact O-OG1 3.28Å; S265-T268 PolarHBondContact O-N 3Å; V266-T268 VanDerWaalsContact C-N 3.28Å; V266-T268 PolarHBondContact O-N 3.23Å; T268-Y270 VanDerWaalsContact C-N 3.31Å; T268-Y270 PolarHBondContact O-N 3Å; T268-T271 WeakPolarHBondContact O-CB 3.16Å; T268-T271 PolarHBondContact O-N 2.86Å; T268-M272 WeakPolarHBondContact O-CG 3.38Å; T268-M272 PolarHBondContact O-N 2.98Å
269	V	95.9	Very high	92.8	Very high	32 Å²	32	11.6 Å²	11.6	19%	0.194	6%	0.062	C	C	.	.	H	α-helix	trans	-58.5	-45	177.9	172	0	0	0	0	111	N205 L208 S209 S265 V266 T271 M272 Y273	N205-V269 HydrophobicContact CB-CG2 3.69Å; N205-V269 WeakPolarHBondContact O-CG2 3.49Å; L208-V269 HydrophobicContact CD2-CG1 3.94Å; L208-V269 HydrophobicContact CD2-CG2 4.48Å; S209-V269 WeakPolarHBondContact OG-CA 3.38Å; S209-V269 WeakPolarHBondContact OG-CG2 3.29Å; S209-V269 PolarHBondContact OG-N 3.32Å; S265-V269 WeakPolarHBondContact O-CG2 3.2Å; S265-V269 PolarHBondContact O-N 3.27Å; V266-V269 PolarHBondContact O-N 3.12Å; V269-T271 PolarHBondContact O-N 2.79Å; V269-M272 WeakPolarHBondContact O-CB 3.25Å; V269-M272 PolarHBondContact O-N 3.42Å; V269-Y273 PolarHBondContact O-N 3.37Å
270	Y	94.6	Very high	93.1	Very high	10 Å²	10	11.9 Å²	11.9	4%	0.039	6%	0.063	C	C	.	.	H	α-helix	trans	-66.7	-37	179.8	-174.9	-99.6	0	0	0	112.7	Q167 L168 L171 V266 I267 T268 M272 Y273 L274 L323	Q167-Y270 PolarHBondContact OE1-OH 2.96Å; L168-Y270 HydrophobicContact CD2-CD1 3.57Å; L168-Y270 HydrophobicContact CD2-CE1 3.27Å; L168-Y270 HydrophobicContact CG-CE1 3.76Å; L171-Y270 VanDerWaalsContact CD2-CB 3.45Å; L171-Y270 HydrophobicContact CD2-CD1 3.64Å; L171-Y270 HydrophobicContact CD2-CD2 3.62Å; L171-Y270 HydrophobicContact CD2-CE1 4.25Å; L171-Y270 HydrophobicContact CD2-CE2 4.22Å; L171-Y270 HydrophobicContact CD2-CG 3.27Å; V266-Y270 PolarHBondContact O-N 3.17Å; I267-Y270 PolarHBondContact O-N 3.49Å; T268-Y270 VanDerWaalsContact C-N 3.31Å; T268-Y270 PolarHBondContact O-N 3Å; Y270-M272 VanDerWaalsContact C-N 3.32Å; Y270-M272 PolarHBondContact O-N 2.88Å; Y270-Y273 HydrophobicContact CD2-CD1 4.15Å; Y270-Y273 HydrophobicContact CE2-CD1 4.03Å; Y270-Y273 HydrophobicContact CE2-CE1 4.35Å; Y270-Y273 WeakPolarHBondContact O-CB 3.35Å; Y270-Y273 PolarHBondContact O-N 3.09Å; Y270-L274 HydrophobicContact CD1-CD1 4.06Å; Y270-L274 HydrophobicContact CD1-CG 4.22Å; Y270-L274 HydrophobicContact CE1-CD1 3.5Å; Y270-L274 HydrophobicContact CE1-CD2 4.33Å; Y270-L274 HydrophobicContact CE1-CG 3.76Å; Y270-L274 PolarHBondContact O-N 2.79Å; Y270-L323 HydrophobicContact CD2-CD1 4.33Å; Y270-L323 HydrophobicContact CE2-CD1 4.01Å
271	T	95.9	Very high	93.1	Very high	1 Å²	1	11.3 Å²	11.3	1%	0.006	6%	0.057	C	C	.	.	H	α-helix	trans	-61.9	-41.9	172.9	-58.1	0	0	0	0	110.6	N236 I267 T268 V269 Y273 L274 T275 I434	N236-T271 HydrophobicContact CB-CG2 3.94Å; I267-T271 WeakPolarHBondContact O-CB 3.3Å; I267-T271 PolarHBondContact O-N 3.32Å; I267-T271 PolarHBondContact O-OG1 3.22Å; T268-T271 WeakPolarHBondContact O-CB 3.16Å; T268-T271 PolarHBondContact O-N 2.86Å; V269-T271 PolarHBondContact O-N 2.79Å; T271-Y273 VanDerWaalsContact C-N 3.32Å; T271-Y273 PolarHBondContact O-N 3.37Å; T271-L274 PolarHBondContact O-N 3.38Å; T271-T275 WeakPolarHBondContact O-CB 3.22Å; T271-T275 PolarHBondContact O-N 3.42Å; T271-T275 PolarHBondContact O-OG1 2.88Å; T271-I434 HydrophobicContact CG2-CD1 3.81Å; T271-I434 HydrophobicContact CG2-CG1 4.48Å
272	M	95.7	Very high	92.8	Very high	5 Å²	5	8.4 Å²	8.4	3%	0.025	4%	0.042	C	C	.	.	H	α-helix	trans	-62.8	-39.6	175.1	-65.2	-51.5	106.6	0	0	111.7	A212 I213 F216 N236 T268 V269 Y270 T275 W276	A212-M272 HydrophobicContact CB-CB 4.15Å; A212-M272 HydrophobicContact CB-CG 4.44Å; I213-M272 HydrophobicContact CD1-SD 3.89Å; I213-M272 HydrophobicContact CG1-CG 4.4Å; I213-M272 HydrophobicContact CG1-SD 3.38Å; I213-M272 WeakPolarHBondContact CG1-SD 3.42Å; F216-M272 HydrophobicContact CE2-CB 4.02Å; F216-M272 WeakPolarHBondContact CE2-O 3.23Å; F216-M272 HydrophobicContact CE2-SD 4.04Å; F216-M272 HydrophobicContact CZ-CB 4.31Å; F216-M272 WeakPolarHBondContact CZ-O 3.47Å; N236-M272 HydrophobicContact CB-CE 4.16Å; T268-M272 WeakPolarHBondContact O-CG 3.38Å; T268-M272 PolarHBondContact O-N 2.98Å; V269-M272 WeakPolarHBondContact O-CB 3.25Å; V269-M272 PolarHBondContact O-N 3.42Å; Y270-M272 VanDerWaalsContact C-N 3.32Å; Y270-M272 PolarHBondContact O-N 2.88Å; M272-T275 PolarHBondContact O-N 3.33Å; M272-W276 WeakPolarHBondContact O-CB 3.4Å; M272-W276 PolarHBondContact O-N 2.9Å
273	Y	94.2	Very high	92.1	Very high	25 Å²	25	10.4 Å²	10.4	10%	0.098	6%	0.055	C	C	.	.	H	α-helix	trans	-60.2	-48.6	172.4	162.9	-102.8	0	0	0	112.5	V269 Y270 T271 T275 W276 S277 I319 G320 L323	V269-Y273 PolarHBondContact O-N 3.37Å; Y270-Y273 HydrophobicContact CD2-CD1 4.15Å; Y270-Y273 HydrophobicContact CE2-CD1 4.03Å; Y270-Y273 HydrophobicContact CE2-CE1 4.35Å; Y270-Y273 WeakPolarHBondContact O-CB 3.35Å; Y270-Y273 PolarHBondContact O-N 3.09Å; T271-Y273 VanDerWaalsContact C-N 3.32Å; T271-Y273 PolarHBondContact O-N 3.37Å; Y273-T275 VanDerWaalsContact C-N 3.3Å; Y273-T275 PolarHBondContact O-N 3.37Å; Y273-W276 HydrophobicContact CD2-CE3 4.18Å; Y273-W276 HydrophobicContact CD2-CZ3 4.45Å; Y273-W276 PolarHBondContact O-N 3.05Å; Y273-S277 VanDerWaalsContact O-CB 3.24Å; Y273-S277 WeakPolarHBondContact O-CB 3.4Å; Y273-S277 PolarHBondContact O-N 3.38Å; Y273-I319 HydrophobicContact CD2-CB 4.38Å; Y273-I319 HydrophobicContact CD2-CG2 3.58Å; Y273-I319 HydrophobicContact CE2-CB 3.88Å; Y273-I319 HydrophobicContact CE2-CG2 3.41Å; Y273-I319 VanDerWaalsContact CE2-CG2 3.41Å; Y273-I319 HydrophobicContact CG-CG2 4.45Å; Y273-G320 WeakPolarHBondContact OH-CA 3.5Å; Y273-G320 PolarHBondContact OH-N 2.96Å; Y273-L323 HydrophobicContact CD1-CD1 3.6Å; Y273-L323 HydrophobicContact CD2-CD1 4.38Å; Y273-L323 HydrophobicContact CE1-CD1 3.38Å; Y273-L323 HydrophobicContact CE2-CD1 4.22Å; Y273-L323 HydrophobicContact CG-CD1 4.11Å
274	L	93.8	Very high	91.4	Very high	5 Å²	5	15.2 Å²	15.2	3%	0.026	8%	0.078	C	C	.	.	H	α-helix	trans	-62.4	-38.3	177.5	-75.6	-176.3	0	0	0	112.1	I164 Y270 T271 S277 A278	I164-L274 HydrophobicContact CG2-CD1 4.48Å; I164-L274 HydrophobicContact CG2-CD2 4.4Å; Y270-L274 HydrophobicContact CD1-CD1 4.06Å; Y270-L274 HydrophobicContact CD1-CG 4.22Å; Y270-L274 HydrophobicContact CE1-CD1 3.5Å; Y270-L274 HydrophobicContact CE1-CD2 4.33Å; Y270-L274 HydrophobicContact CE1-CG 3.76Å; Y270-L274 PolarHBondContact O-N 2.79Å; T271-L274 PolarHBondContact O-N 3.38Å; L274-S277 PolarHBondContact O-N 3.18Å; L274-A278 WeakPolarHBondContact O-CB 3.45Å; L274-A278 PolarHBondContact O-N 3.3Å
275	T	95	Very high	90.3	Very high	0 Å²	0	20.4 Å²	20.4	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-61.9	-49.8	176.7	-49.8	0	0	0	0	110.5	I233 N236 T271 M272 Y273 S277 A278 M279	I233-T275 HydrophobicContact CG1-CG2 4.36Å; N236-T275 PolarHBondContact ND2-OG1 3.11Å; T271-T275 WeakPolarHBondContact O-CB 3.22Å; T271-T275 PolarHBondContact O-N 3.42Å; T271-T275 PolarHBondContact O-OG1 2.88Å; M272-T275 PolarHBondContact O-N 3.33Å; Y273-T275 VanDerWaalsContact C-N 3.3Å; Y273-T275 PolarHBondContact O-N 3.37Å; T275-S277 VanDerWaalsContact C-N 3.35Å; T275-S277 PolarHBondContact O-N 3.36Å; T275-A278 WeakPolarHBondContact O-CB 3.4Å; T275-A278 PolarHBondContact O-N 2.93Å; T275-M279 HydrophobicContact CG2-CE 4.01Å; T275-M279 HydrophobicContact CG2-SD 4.32Å; T275-M279 WeakPolarHBondContact O-CG 3.4Å; T275-M279 PolarHBondContact O-N 3.3Å
276	W	92.4	Very high	89.4	Confident	41 Å²	41	25.7 Å²	25.7	16%	0.155	14%	0.138	C	C	.	.	H	α-helix	trans	-60.3	-44	176.2	177.5	48.8	0	0	0	113	F216 Y220 M272 Y273 A278 M279 T280 L291 A315 Q316 I319	F216-W276 HydrophobicContact CE1-CB 3.59Å; F216-W276 AromaticContact CE1-CD1 3.92Å; F216-W276 AromaticContact CE1-CG 3.87Å; F216-W276 HydrophobicContact CE1-CG 3.87Å; F216-W276 HydrophobicContact CE2-CB 4.45Å; F216-W276 HydrophobicContact CZ-CB 3.54Å; F216-W276 HydrophobicContact CZ-CG 4.28Å; Y220-W276 AromaticContact CE2-CD1 3.84Å; Y220-W276 AromaticContact CZ-CD1 3.75Å; Y220-W276 AromaticContact CZ-NE1 3.74Å; Y220-W276 PolarHBondContact OH-NE1 2.87Å; M272-W276 WeakPolarHBondContact O-CB 3.4Å; M272-W276 PolarHBondContact O-N 2.9Å; Y273-W276 HydrophobicContact CD2-CE3 4.18Å; Y273-W276 HydrophobicContact CD2-CZ3 4.45Å; Y273-W276 PolarHBondContact O-N 3.05Å; W276-A278 PolarHBondContact O-N 3.37Å; W276-M279 PolarHBondContact O-N 3.2Å; W276-T280 PolarHBondContact NE1-OG1 2.88Å; W276-T280 WeakPolarHBondContact O-CB 3.47Å; W276-T280 PolarHBondContact O-N 3.36Å; W276-T280 PolarHBondContact O-OG1 2.9Å; W276-L291 HydrophobicContact CZ2-CD1 4.4Å; W276-A315 HydrophobicContact CH2-CB 3.75Å; W276-A315 HydrophobicContact CZ2-CB 4.26Å; W276-Q316 HydrophobicContact CH2-CB 4.48Å; W276-Q316 HydrophobicContact CZ3-CB 4.42Å; W276-I319 HydrophobicContact CH2-CD1 3.98Å; W276-I319 HydrophobicContact CZ3-CD1 3.59Å
277	S	90.7	Very high	88.7	Confident	6 Å²	6	25.3 Å²	25.3	4%	0.042	14%	0.136	C	C	.	.	H	α-helix	trans	-63.5	-32	177.5	-164.1	0	0	0	0	111.7	Y273 L274 T275 Q316 K426	Y273-S277 VanDerWaalsContact O-CB 3.24Å; Y273-S277 WeakPolarHBondContact O-CB 3.4Å; Y273-S277 PolarHBondContact O-N 3.38Å; L274-S277 PolarHBondContact O-N 3.18Å; T275-S277 VanDerWaalsContact C-N 3.35Å; T275-S277 PolarHBondContact O-N 3.36Å; S277-Q316 PolarHBondContact O-OE1 3.47Å; S277-K426 WeakPolarHBondContact O-CD 3.37Å; S277-K426 PolarHBondContact O-NZ 3.12Å; S277-K426 WeakPolarHBondContact OG-CE 3.39Å; S277-K426 PolarHBondContact OG-NZ 3.15Å
278	A	91.4	Very high	87.9	Confident	0 Å²	0	26.6 Å²	26.6	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-72.5	-49.4	174.5	0	0	0	0	0	111.8	L274 T275 W276 T280 N281 E282 V423 K426 I427	L274-A278 WeakPolarHBondContact O-CB 3.45Å; L274-A278 PolarHBondContact O-N 3.3Å; T275-A278 WeakPolarHBondContact O-CB 3.4Å; T275-A278 PolarHBondContact O-N 2.93Å; W276-A278 PolarHBondContact O-N 3.37Å; A278-T280 VanDerWaalsContact C-N 3.28Å; A278-T280 PolarHBondContact O-N 3.41Å; A278-N281 CarbonylContact O-C 3.55Å; A278-N281 WeakPolarHBondContact O-CA 3.11Å; A278-N281 WeakPolarHBondContact O-CB 3.26Å; A278-N281 PolarHBondContact O-N 3.43Å; A278-E282 PolarHBondContact O-N 2.86Å; A278-V423 HydrophobicContact CB-CG1 4.03Å; A278-V423 WeakPolarHBondContact O-CG2 3.38Å; A278-K426 HydrophobicContact CB-CB 3.78Å; A278-K426 HydrophobicContact CB-CD 4.33Å; A278-I427 HydrophobicContact CB-CD1 3.58Å; A278-I427 HydrophobicContact CB-CG1 3.67Å
279	M	90.1	Very high	86.7	Confident	0 Å²	0	27.6 Å²	27.6	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-64.2	-33.2	-179.5	-63.3	-178.4	-60.4	0	0	112.3	F216 Y220 N229 I233 T275 W276 N281 E282	F216-M279 HydrophobicContact CB-CE 3.88Å; F216-M279 HydrophobicContact CD1-CE 3.85Å; F216-M279 HydrophobicContact CD2-CE 3.9Å; F216-M279 HydrophobicContact CE1-CE 4.41Å; F216-M279 HydrophobicContact CE2-CE 4.43Å; F216-M279 HydrophobicContact CG-CE 3.6Å; Y220-M279 HydrophobicContact CD1-CB 3.68Å; Y220-M279 HydrophobicContact CD2-CE 4.38Å; Y220-M279 HydrophobicContact CE1-CB 4.08Å; Y220-M279 HydrophobicContact CG-CB 4.28Å; Y220-M279 HydrophobicContact CG-CE 4.21Å; Y220-M279 HydrophobicContact CG-SD 4.34Å; N229-M279 HydrophobicContact CB-CG 4.42Å; N229-M279 HydrophobicContact CB-SD 4Å; N229-M279 WeakPolarHBondContact OD1-CG 3.41Å; I233-M279 HydrophobicContact CD1-CE 4.4Å; I233-M279 HydrophobicContact CD1-SD 3.77Å; I233-M279 HydrophobicContact CG1-CE 4.17Å; I233-M279 HydrophobicContact CG1-SD 3.67Å; T275-M279 HydrophobicContact CG2-CE 4.01Å; T275-M279 HydrophobicContact CG2-SD 4.32Å; T275-M279 WeakPolarHBondContact O-CG 3.4Å; T275-M279 PolarHBondContact O-N 3.3Å; W276-M279 PolarHBondContact O-N 3.2Å; M279-N281 PolarHBondContact O-N 3.26Å; M279-N281 VanDerWaalsContact O-N 3.17Å; M279-E282 WeakPolarHBondContact O-CB 3.38Å; M279-E282 PolarHBondContact O-N 2.87Å
280	T	85.4	Confident	85.2	Confident	14 Å²	14	28.3 Å²	28.3	9%	0.086	16%	0.156	C	C	.	.	T	Hydrogen-bonded Turn	trans	-67.4	-12.3	173.8	-54.6	0	0	0	0	112.9	Y220 W276 A278 N288 Q316	Y220-T280 PolarHBondContact OH-OG1 3.35Å; W276-T280 PolarHBondContact NE1-OG1 2.88Å; W276-T280 WeakPolarHBondContact O-CB 3.47Å; W276-T280 PolarHBondContact O-N 3.36Å; W276-T280 PolarHBondContact O-OG1 2.9Å; A278-T280 VanDerWaalsContact C-N 3.28Å; A278-T280 PolarHBondContact O-N 3.41Å; T280-N288 VanDerWaalsContact C-ND2 3.27Å; T280-N288 WeakPolarHBondContact CA-OD1 3.46Å; T280-N288 PolarHBondContact O-ND2 2.86Å; T280-N288 PolarHBondContact O-OD1 3.12Å; T280-Q316 HydrophobicContact CG2-CG 4.34Å
281	N	83.6	Confident	83.4	Confident	0 Å²	0	31 Å²	31	0%	0	17%	0.171	C	C	.	.	T	Hydrogen-bonded Turn	trans	-106.4	13.5	173	-74.3	-2.4	0	0	0	112.5	A278 M279 Q316 S418 A422 V423 K426	A278-N281 CarbonylContact O-C 3.55Å; A278-N281 WeakPolarHBondContact O-CA 3.11Å; A278-N281 WeakPolarHBondContact O-CB 3.26Å; A278-N281 PolarHBondContact O-N 3.43Å; M279-N281 PolarHBondContact O-N 3.26Å; M279-N281 VanDerWaalsContact O-N 3.17Å; N281-Q316 PolarHBondContact OD1-NE2 2.91Å; N281-S418 WeakPolarHBondContact CA-OG 3.4Å; N281-S418 WeakPolarHBondContact O-CB 3.28Å; N281-S418 PolarHBondContact O-OG 3.21Å; N281-A422 HydrophobicContact CB-CB 4.29Å; N281-V423 HydrophobicContact CB-CG2 4.24Å; N281-V423 VanDerWaalsContact O-CG2 3.23Å; N281-V423 WeakPolarHBondContact O-CG2 3.4Å; N281-K426 PolarHBondContact ND2-NZ 2.91Å
282	E	84.9	Confident	81.4	Confident	7 Å²	7	34.2 Å²	34.2	3%	0.033	19%	0.187	C	C	.	.			trans	-69.8	134.6	172.2	-167.9	-179.4	-173.1	0	0	110.3	N229 A278 M279 E284 C287 N288 W420	N229-E282 PolarHBondContact ND2-OE2 3.44Å; N229-E282 PolarHBondContact OD1-OE2 3.45Å; A278-E282 PolarHBondContact O-N 2.86Å; M279-E282 WeakPolarHBondContact O-CB 3.38Å; M279-E282 PolarHBondContact O-N 2.87Å; E282-E284 VanDerWaalsContact C-N 3.3Å; E282-E284 HydrophobicContact CG-CB 4.37Å; E282-E284 PolarHBondContact O-N 2.65Å; E282-C287 WeakPolarHBondContact OE2-CB 3.35Å; E282-N288 HydrophobicContact CB-CB 4.32Å; E282-N288 PolarHBondContact O-ND2 3Å; E282-W420 HydrophobicContact CG-CH2 3.72Å; E282-W420 HydrophobicContact CG-CZ2 3.97Å; E282-W420 HydrophobicContact CG-CZ3 4.25Å; E282-W420 VanDerWaalsContact OE1-CH2 3.29Å; E282-W420 WeakPolarHBondContact OE1-CH2 3.26Å
283	P	79	Confident	79.6	Confident	44 Å²	44	37.1 Å²	37.1	29%	0.286	21%	0.208	S	C	.	.	S	Bend	trans	-68.1	-25.4	179.8	23	-31.6	0	0	0	114.3	T285 S418 W420	P283-T285 PolarHBondContact O-N 3.13Å; P283-S418 WeakPolarHBondContact CB-O 3.42Å; P283-W420 HydrophobicContact CG-CD2 4.19Å; P283-W420 HydrophobicContact CG-CG 4.09Å; P283-W420 HydrophobicContact CG-CZ2 4.29Å
284	E	78.2	Confident	78	Confident	100 Å²	100	38 Å²	38	47%	0.467	21%	0.214	S	C	.	.			trans	-75.1	106.4	-178.9	-69.8	-62.4	152	0	0	110.4	E282 N286 C287 N288	E282-E284 VanDerWaalsContact C-N 3.3Å; E282-E284 HydrophobicContact CG-CB 4.37Å; E282-E284 PolarHBondContact O-N 2.65Å; E284-N286 PolarHBondContact O-N 3.4Å; E284-N286 VanDerWaalsContact O-N 3.12Å; E284-C287 HydrophobicContact CB-CB 4.22Å; E284-C287 PolarHBondContact O-N 3.45Å; E284-N288 PolarHBondContact O-N 2.97Å; E284-N288 VanDerWaalsContact O-N 3.13Å
285	T	71.3	Confident	76.4	Confident	111 Å²	111	43 Å²	43	68%	0.681	24%	0.24	S	C	*	.	T	Hydrogen-bonded Turn	trans	-61.2	-25.4	-175.6	55.3	0	0	0	0	113.5	P283 C287	P283-T285 PolarHBondContact O-N 3.13Å; T285-C287 VanDerWaalsContact C-N 3.29Å
286	N	78.1	Confident	74	Confident	111 Å²	111	45.6 Å²	45.6	59%	0.594	27%	0.266	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.3	-24.6	176.4	-66.5	-25.1	0	0	0	112.6	H222 E284	H222-N286 PolarHBondContact CD2-O 3.21Å; H222-N286 PolarHBondContact NE2-O 2.64Å; E284-N286 PolarHBondContact O-N 3.4Å; E284-N286 VanDerWaalsContact O-N 3.12Å
287	C	80.5	Confident	71.8	Confident	8 Å²	8	51.5 Å²	51.5	5%	0.054	29%	0.29	C	S	.	.	T	Hydrogen-bonded Turn	trans	-101.6	-11.5	-177.7	-58.7	0	0	0	0	112.6	Y220 C226 N229 E282 E284 T285 P289	Y220-C287 WeakPolarHBondContact CD1-O 3.27Å; C226-C287 WeakPolarHBondContact CA-SG 3.46Å; C226-C287 HydrophobicContact CB-CB 3.72Å; C226-C287 WeakPolarHBondContact CB-SG 3.39Å; C226-C287 WeakPolarHBondContact SG-CA 3.39Å; C226-C287 WeakPolarHBondContact SG-CB 3.45Å; C226-C287 CovalentContact SG-SG 2.03Å; C226-C287 PolarHBondContact SG-SG 2.87Å; N229-C287 PolarHBondContact ND2-O 3.41Å; E282-C287 WeakPolarHBondContact OE2-CB 3.35Å; E284-C287 HydrophobicContact CB-CB 4.22Å; E284-C287 PolarHBondContact O-N 3.45Å; T285-C287 VanDerWaalsContact C-N 3.29Å; C287-P289 VanDerWaalsContact C-CD 3.47Å; C287-P289 WeakPolarHBondContact O-CD 2.86Å
288	N	78	Confident	69.3	Low	31 Å²	31	58 Å²	58	17%	0.166	32%	0.324	C	S	.	.	S	Bend	trans	-123.2	73.7	178.9	178.8	11	0	0	0	110.7	T280 E282 E284 S290	T280-N288 VanDerWaalsContact C-ND2 3.27Å; T280-N288 WeakPolarHBondContact CA-OD1 3.46Å; T280-N288 PolarHBondContact O-ND2 2.86Å; T280-N288 PolarHBondContact O-OD1 3.12Å; E282-N288 HydrophobicContact CB-CB 4.32Å; E282-N288 PolarHBondContact O-ND2 3Å; E284-N288 PolarHBondContact O-N 2.97Å; E284-N288 VanDerWaalsContact O-N 3.13Å; N288-S290 PolarHBondContact O-N 3.34Å
289	P	71.4	Confident	66.7	Low	29 Å²	29	62.7 Å²	62.7	19%	0.188	35%	0.352	C	S	.	.			trans	-68.1	132.9	173.5	27.2	-32.1	0	0	0	110.2	Y219 C287 I294	Y219-P289 VanDerWaalsContact O-CG 3.26Å; Y219-P289 WeakPolarHBondContact O-CG 3.36Å; C287-P289 VanDerWaalsContact C-CD 3.47Å; C287-P289 WeakPolarHBondContact O-CD 2.86Å; P289-I294 HydrophobicContact CB-CD1 4.39Å; P289-I294 HydrophobicContact CB-CG1 4.11Å; P289-I294 HydrophobicContact CG-CD1 4.03Å; P289-I294 HydrophobicContact CG-CG1 4.13Å
290	S	65.6	Low	64	Low	46 Å²	46	68.3 Å²	68.3	32%	0.322	39%	0.387	S	S	.	.			trans	-58.4	146.2	171.9	72.7	0	0	0	0	110.6	N288 L292 S293 I294	N288-S290 PolarHBondContact O-N 3.34Å; S290-L292 PolarHBondContact O-N 3.33Å; S290-L292 VanDerWaalsContact O-N 3.1Å; S290-S293 PolarHBondContact N-OG 3.34Å; S290-S293 WeakPolarHBondContact O-CA 3.49Å; S290-S293 PolarHBondContact O-N 2.77Å; S290-S293 PolarHBondContact O-OG 3.25Å; S290-S293 PolarHBondContact OG-N 3.05Å; S290-S293 VanDerWaalsContact OG-N 3.14Å; S290-S293 PolarHBondContact OG-OG 3.49Å; S290-I294 PolarHBondContact O-N 3.06Å
291	L	56.2	Low	61.4	Low	68 Å²	68	70.8 Å²	70.8	36%	0.356	41%	0.405	S	S	.	.	H	α-helix	trans	-55.1	-33.6	176.5	-156.4	168.7	0	0	0	111.3	W276 I294 I295 A315	W276-L291 HydrophobicContact CZ2-CD1 4.4Å; L291-I294 PolarHBondContact O-N 3.04Å; L291-I295 HydrophobicContact CD2-CD1 3.14Å; L291-I295 HydrophobicContact CD2-CG1 3.72Å; L291-I295 PolarHBondContact O-N 3.07Å; L291-A315 HydrophobicContact CD1-CB 3.43Å; L291-A315 VanDerWaalsContact CD1-CB 3.43Å
292	L	53.3	Low	58.8	Low	68 Å²	68	77.4 Å²	77.4	36%	0.356	45%	0.446	S	S	.	.	H	α-helix	trans	-66	-40.1	176.6	-165.1	70.2	0	0	0	112.5	S290 I294 I295 G296 Y297	S290-L292 PolarHBondContact O-N 3.33Å; S290-L292 VanDerWaalsContact O-N 3.1Å; L292-I294 VanDerWaalsContact C-N 3.3Å; L292-I294 PolarHBondContact O-N 3.43Å; L292-I295 PolarHBondContact O-N 3.48Å; L292-G296 PolarHBondContact O-N 3.1Å; L292-Y297 HydrophobicContact CD1-CD2 4.03Å; L292-Y297 HydrophobicContact CD1-CG 4.2Å; L292-Y297 PolarHBondContact O-N 2.62Å
293	S	59.6	Low	56.3	Low	65 Å²	65	82.4 Å²	82.4	46%	0.455	48%	0.477	S	S	.	.	H	α-helix	trans	-65.6	-32.5	171.8	49.2	0	0	0	0	112.7	S290 G296	S290-S293 PolarHBondContact N-OG 3.34Å; S290-S293 WeakPolarHBondContact O-CA 3.49Å; S290-S293 PolarHBondContact O-N 2.77Å; S290-S293 PolarHBondContact O-OG 3.25Å; S290-S293 PolarHBondContact OG-N 3.05Å; S290-S293 VanDerWaalsContact OG-N 3.14Å; S290-S293 PolarHBondContact OG-OG 3.49Å; S293-G296 PolarHBondContact O-N 3.08Å
294	I	59.5	Low	54.2	Low	45 Å²	45	85.6 Å²	85.6	23%	0.231	50%	0.497	C	S	.	.	H	α-helix	trans	-71.3	-39.3	176.9	-66.1	165.5	0	0	0	111.7	Y219 P289 S290 L291 L292 G296	Y219-I294 HydrophobicContact CD1-CB 4.42Å; Y219-I294 HydrophobicContact CD1-CD1 4.39Å; Y219-I294 HydrophobicContact CD1-CG1 3.93Å; Y219-I294 HydrophobicContact CD1-CG2 3.8Å; Y219-I294 HydrophobicContact CD2-CG2 4.16Å; Y219-I294 HydrophobicContact CE1-CB 4.47Å; Y219-I294 HydrophobicContact CE1-CG1 4.46Å; Y219-I294 HydrophobicContact CE1-CG2 3.55Å; Y219-I294 HydrophobicContact CE2-CG2 3.93Å; Y219-I294 HydrophobicContact CG-CD1 4.14Å; Y219-I294 HydrophobicContact CG-CG1 4.19Å; Y219-I294 HydrophobicContact CG-CG2 4.1Å; P289-I294 HydrophobicContact CB-CD1 4.39Å; P289-I294 HydrophobicContact CB-CG1 4.11Å; P289-I294 HydrophobicContact CG-CD1 4.03Å; P289-I294 HydrophobicContact CG-CG1 4.13Å; S290-I294 PolarHBondContact O-N 3.06Å; L291-I294 PolarHBondContact O-N 3.04Å; L292-I294 VanDerWaalsContact C-N 3.3Å; L292-I294 PolarHBondContact O-N 3.43Å; I294-G296 PolarHBondContact O-N 3.24Å
295	I	60.5	Low	51.8	Low	109 Å²	109	87.5 Å²	87.5	56%	0.559	50%	0.504	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.5	-3.3	179.2	-69.5	177.9	0	0	0	112.4	L291 L292 Y297	L291-I295 HydrophobicContact CD2-CD1 3.14Å; L291-I295 HydrophobicContact CD2-CG1 3.72Å; L291-I295 PolarHBondContact O-N 3.07Å; L292-I295 PolarHBondContact O-N 3.48Å; I295-Y297 HydrophobicContact CG2-CD2 3.92Å; I295-Y297 HydrophobicContact CG2-CE2 4.05Å
296	G	45.2	Very low	49.9	Very low	54 Å²	54	91.6 Å²	91.6	56%	0.557	52%	0.515	S	S	*	.	T	Hydrogen-bonded Turn	trans	81.9	16.3	173.6	0	0	0	0	0	114.2	L292 S293 I294 N298	L292-G296 PolarHBondContact O-N 3.1Å; S293-G296 PolarHBondContact O-N 3.08Å; I294-G296 PolarHBondContact O-N 3.24Å; G296-N298 VanDerWaalsContact C-N 3.25Å; G296-N298 PolarHBondContact O-N 3.04Å
297	Y	46.2	Very low	48.2	Very low	166 Å²	166	89.1 Å²	89.1	65%	0.651	52%	0.516	S	S	*	.			trans	-74.8	87.4	162.5	-79.9	-80.1	0	0	0	108.2	L292 I295 T299	L292-Y297 HydrophobicContact CD1-CD2 4.03Å; L292-Y297 HydrophobicContact CD1-CG 4.2Å; L292-Y297 PolarHBondContact O-N 2.62Å; I295-Y297 HydrophobicContact CG2-CD2 3.92Å; I295-Y297 HydrophobicContact CG2-CE2 4.05Å; Y297-T299 VanDerWaalsContact C-N 3.3Å; Y297-T299 PolarHBondContact O-N 3.23Å
298	N	37.8	Very low	46.1	Very low	141 Å²	141	94.4 Å²	94.4	75%	0.754	54%	0.54	S	S	*	.			trans	-61.8	86	173.4	-101	-11.3	0	0	0	110.3	G296 T300	G296-N298 VanDerWaalsContact C-N 3.25Å; G296-N298 PolarHBondContact O-N 3.04Å; N298-T300 PolarHBondContact O-N 3.39Å; N298-T300 VanDerWaalsContact O-N 3.16Å
299	T	37.3	Very low	44.3	Very low	99 Å²	99	95.9 Å²	95.9	61%	0.607	55%	0.553	S	S	*	*			trans	-79.2	82.9	150.6	43.8	0	0	0	0	107.5	Y297 S301	Y297-T299 VanDerWaalsContact C-N 3.3Å; Y297-T299 PolarHBondContact O-N 3.23Å; T299-S301 PolarHBondContact O-N 2.97Å
300	T	32.6	Very low	43.3	Very low	118 Å²	118	97.1 Å²	97.1	72%	0.724	56%	0.56	S	S	*	*			trans	-63.3	81.6	160.8	40.8	0	0	0	0	108.6	N298	N298-T300 PolarHBondContact O-N 3.39Å; N298-T300 VanDerWaalsContact O-N 3.16Å
301	S	30.3	Very low	42.7	Very low	67 Å²	67	98.3 Å²	98.3	47%	0.469	56%	0.56	S	S	.	*			trans	-162.6	94	160.9	-74.7	0	0	0	0	108.4	T299	T299-S301 PolarHBondContact O-N 2.97Å
302	T	29.5	Very low	42.5	Very low	139 Å²	139	101.2 Å²	101.2	85%	0.853	57%	0.566	S	S	*	*	S	Bend	trans	-49.4	138.7	144.8	38.8	0	0	0	0	108.6
303	V	33	Very low	42.8	Very low	112 Å²	112	102 Å²	102	68%	0.679	57%	0.565	S	S	*	*	S	Bend	trans	81.4	114.5	-168.9	-166.9	0	0	0	0	112.9	K305	V303-K305 PolarHBondContact O-N 3.44Å
304	P	33.5	Very low	43.3	Very low	111 Å²	111	100.4 Å²	100.4	72%	0.721	55%	0.55	S	S	*	.			trans	-60.9	111.3	165.7	27	-30.4	0	0	0	106.7	E306	P304-E306 PolarHBondContact O-N 2.84Å
305	K	28.9	Very low	44.1	Very low	140 Å²	140	99.6 Å²	99.6	61%	0.609	55%	0.55	S	S	*	.			trans	-55.3	134.7	165.5	-75.1	-178	176.9	176.1	0	107	V303 G307 Q308	V303-K305 PolarHBondContact O-N 3.44Å; K305-G307 PolarHBondContact O-N 2.95Å; K305-G307 VanDerWaalsContact O-N 3.07Å; K305-Q308 PolarHBondContact O-N 3.11Å; K305-Q308 VanDerWaalsContact O-N 3.1Å
306	E	30.6	Very low	45.2	Very low	197 Å²	197	94.7 Å²	94.7	92%	0.921	53%	0.525	S	S	*	.	T	Hydrogen-bonded Turn	trans	-38.9	117.9	174.9	-77.4	-176.7	138.6	0	0	110.3	P304	P304-E306 PolarHBondContact O-N 2.84Å
307	G	41.9	Very low	47	Very low	59 Å²	59	92.6 Å²	92.6	61%	0.608	50%	0.503	S	S	*	.	T	Hydrogen-bonded Turn	trans	96.3	4.8	175.5	0	0	0	0	0	117.2	K305 S309	K305-G307 PolarHBondContact O-N 2.95Å; K305-G307 VanDerWaalsContact O-N 3.07Å; G307-S309 PolarHBondContact O-N 2.92Å
308	Q	37.4	Very low	48.9	Very low	118 Å²	118	88.2 Å²	88.2	55%	0.551	49%	0.49	S	S	*	.			trans	-85.1	106.7	174.8	-147.3	160.4	-7.6	0	0	110.8	K305 V310	K305-Q308 PolarHBondContact O-N 3.11Å; K305-Q308 VanDerWaalsContact O-N 3.1Å; Q308-V310 PolarHBondContact O-N 3.19Å
309	S	39.6	Very low	51.4	Low	63 Å²	63	84.7 Å²	84.7	44%	0.441	47%	0.47	S	S	.	.			trans	-40.6	126.7	-178.8	55.5	0	0	0	0	113.1	G307 Q311	G307-S309 PolarHBondContact O-N 2.92Å; S309-Q311 PolarHBondContact O-N 3.34Å
310	V	50.1	Low	53.9	Low	55 Å²	55	80 Å²	80	33%	0.333	44%	0.442	S	S	.	.			trans	-48.5	128.3	157.9	-111	0	0	0	0	107.1	I83 Q308 W312 M416	I83-V310 HydrophobicContact CG2-CG2 3.14Å; Q308-V310 PolarHBondContact O-N 3.19Å; V310-W312 PolarHBondContact O-N 3.08Å; V310-M416 HydrophobicContact CG1-SD 4.2Å; V310-M416 HydrophobicContact CG2-SD 4.5Å
311	Q	52.8	Low	56.8	Low	70 Å²	70	75.4 Å²	75.4	33%	0.327	41%	0.413	S	S	.	.			trans	-50.4	108.6	178.3	-91.7	-174.4	-55.3	0	0	109	S309 W313	S309-Q311 PolarHBondContact O-N 3.34Å; Q311-W313 PolarHBondContact O-N 3.22Å
312	W	52	Low	59.8	Low	129 Å²	129	76.5 Å²	76.5	49%	0.489	41%	0.412	S	S	.	.	S	Bend	trans	-67.2	-27.4	-169.3	63.1	109	0	0	0	111.5	P59 V310	P59-W312 HydrophobicContact CG-CD2 4.39Å; V310-W312 PolarHBondContact O-N 3.08Å
313	W	61.3	Low	62.7	Low	86 Å²	86	71.8 Å²	71.8	33%	0.326	38%	0.382	S	S	.	.			trans	-135.1	107	-178.5	-80.4	56.7	0	0	0	111.2	C54 Q311 I318 L321	C54-W313 HydrophobicContact CB-CZ2 3.98Å; Q311-W313 PolarHBondContact O-N 3.22Å; W313-I318 HydrophobicContact CE3-CB 4.47Å; W313-I318 HydrophobicContact CE3-CD1 4.11Å; W313-I318 HydrophobicContact CE3-CG1 3.33Å; W313-I318 HydrophobicContact CZ3-CB 4.47Å; W313-I318 HydrophobicContact CZ3-CG1 3.69Å; W313-L321 HydrophobicContact CH2-CD2 3.88Å; W313-L321 HydrophobicContact CZ3-CD2 4.29Å
314	H	69.7	Low	65.6	Low	30 Å²	30	66.5 Å²	66.5	14%	0.139	35%	0.35	C	S	.	.			trans	-80.8	143.5	165.4	-65.1	-87	0	0	0	109.6	Q316 G317 I318 N406	H314-Q316 HydrophobicContact CB-CG 3.67Å; H314-Q316 PolarHBondContact O-N 2.99Å; H314-G317 PolarHBondContact O-N 3.15Å; H314-I318 PolarHBondContact O-N 2.86Å; H314-N406 PolarHBondContact CD2-OD1 2.72Å; H314-N406 VanDerWaalsContact CD2-OD1 3.3Å
315	A	76.7	Confident	68.5	Low	28 Å²	28	63.5 Å²	63.5	23%	0.231	33%	0.327	C	S	.	.	H	α-helix	trans	-55.3	-28.8	177.9	0	0	0	0	0	112.8	W276 L291 G317 I318 I319	W276-A315 HydrophobicContact CH2-CB 3.75Å; W276-A315 HydrophobicContact CZ2-CB 4.26Å; L291-A315 HydrophobicContact CD1-CB 3.43Å; L291-A315 VanDerWaalsContact CD1-CB 3.43Å; A315-G317 VanDerWaalsContact C-N 3.31Å; A315-G317 PolarHBondContact O-N 3.15Å; A315-I318 PolarHBondContact O-N 3.13Å; A315-I319 PolarHBondContact O-N 3.46Å; A315-I319 VanDerWaalsContact O-N 3.11Å
316	Q	82.6	Confident	71.5	Confident	7 Å²	7	62.2 Å²	62.2	3%	0.033	33%	0.326	C	S	.	.	H	α-helix	trans	-57.8	-40.5	171.7	65.4	170.8	-11.6	0	0	113	W276 S277 T280 N281 H314 G320	W276-Q316 HydrophobicContact CH2-CB 4.48Å; W276-Q316 HydrophobicContact CZ3-CB 4.42Å; S277-Q316 PolarHBondContact O-OE1 3.47Å; T280-Q316 HydrophobicContact CG2-CG 4.34Å; N281-Q316 PolarHBondContact OD1-NE2 2.91Å; H314-Q316 HydrophobicContact CB-CG 3.67Å; H314-Q316 PolarHBondContact O-N 2.99Å; Q316-G320 PolarHBondContact O-N 3.28Å
317	G	83.2	Confident	74.4	Confident	10 Å²	10	53.3 Å²	53.3	10%	0.103	29%	0.286	C	S	.	.	H	α-helix	trans	-71.4	-36.8	-178.9	0	0	0	0	0	111.9	H314 A315 L321	H314-G317 PolarHBondContact O-N 3.15Å; A315-G317 VanDerWaalsContact C-N 3.31Å; A315-G317 PolarHBondContact O-N 3.15Å; G317-L321 VanDerWaalsContact O-CB 3.27Å; G317-L321 WeakPolarHBondContact O-CB 3.41Å; G317-L321 PolarHBondContact O-N 3.1Å
318	I	86.3	Confident	76.7	Confident	73 Å²	73	51 Å²	51	37%	0.374	26%	0.26	S	S	.	.	H	α-helix	trans	-61.2	-53.3	174.5	-61	171.4	0	0	0	110.2	W313 H314 A315 G320 L321 I322	W313-I318 HydrophobicContact CE3-CB 4.47Å; W313-I318 HydrophobicContact CE3-CD1 4.11Å; W313-I318 HydrophobicContact CE3-CG1 3.33Å; W313-I318 HydrophobicContact CZ3-CB 4.47Å; W313-I318 HydrophobicContact CZ3-CG1 3.69Å; H314-I318 PolarHBondContact O-N 2.86Å; A315-I318 PolarHBondContact O-N 3.13Å; I318-G320 VanDerWaalsContact C-N 3.32Å; I318-G320 PolarHBondContact O-N 2.9Å; I318-L321 PolarHBondContact O-N 2.85Å; I318-I322 HydrophobicContact CG2-CD1 3.98Å; I318-I322 WeakPolarHBondContact O-CG1 3.17Å; I318-I322 PolarHBondContact O-N 2.95Å
319	I	89.9	Confident	79.2	Confident	67 Å²	67	48.6 Å²	48.6	34%	0.344	25%	0.248	S	C	.	.	H	α-helix	trans	-65.8	-40.9	-176.8	-66.8	164.4	0	0	0	109.8	Y273 W276 A315 L321 I322 L323	Y273-I319 HydrophobicContact CD2-CB 4.38Å; Y273-I319 HydrophobicContact CD2-CG2 3.58Å; Y273-I319 HydrophobicContact CE2-CB 3.88Å; Y273-I319 HydrophobicContact CE2-CG2 3.41Å; Y273-I319 VanDerWaalsContact CE2-CG2 3.41Å; Y273-I319 HydrophobicContact CG-CG2 4.45Å; W276-I319 HydrophobicContact CH2-CD1 3.98Å; W276-I319 HydrophobicContact CZ3-CD1 3.59Å; A315-I319 PolarHBondContact O-N 3.46Å; A315-I319 VanDerWaalsContact O-N 3.11Å; I319-L321 PolarHBondContact O-N 3.39Å; I319-I322 PolarHBondContact O-N 2.9Å; I319-L323 HydrophobicContact CG2-CD1 3.9Å; I319-L323 HydrophobicContact CG2-CG 4.39Å; I319-L323 VanDerWaalsContact O-CG 3.31Å; I319-L323 WeakPolarHBondContact O-CG 3.32Å; I319-L323 PolarHBondContact O-N 3.01Å
320	G	90.6	Very high	81.6	Confident	0 Å²	0	47.7 Å²	47.7	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-59.6	-42.4	173.8	0	0	0	0	0	113.3	Y273 Q316 I318 L323 F324	Y273-G320 WeakPolarHBondContact OH-CA 3.5Å; Y273-G320 PolarHBondContact OH-N 2.96Å; Q316-G320 PolarHBondContact O-N 3.28Å; I318-G320 VanDerWaalsContact C-N 3.32Å; I318-G320 PolarHBondContact O-N 2.9Å; G320-L323 PolarHBondContact O-N 3.09Å; G320-F324 VanDerWaalsContact O-CB 3.3Å; G320-F324 WeakPolarHBondContact O-CB 3.4Å; G320-F324 PolarHBondContact O-N 2.95Å
321	L	92.2	Very high	83.3	Confident	23 Å²	23	45.5 Å²	45.5	12%	0.12	22%	0.222	C	C	.	.	H	α-helix	trans	-63.3	-44.6	175.1	178.4	60.2	0	0	0	111.6	V50 W313 G317 I318 I319 L323 F324 L325 I400	V50-L321 HydrophobicContact CG1-CD1 3.58Å; W313-L321 HydrophobicContact CH2-CD2 3.88Å; W313-L321 HydrophobicContact CZ3-CD2 4.29Å; G317-L321 VanDerWaalsContact O-CB 3.27Å; G317-L321 WeakPolarHBondContact O-CB 3.41Å; G317-L321 PolarHBondContact O-N 3.1Å; I318-L321 PolarHBondContact O-N 2.85Å; I319-L321 PolarHBondContact O-N 3.39Å; L321-L323 PolarHBondContact O-N 2.92Å; L321-F324 HydrophobicContact CD1-CD1 4.3Å; L321-F324 WeakPolarHBondContact O-CB 3.44Å; L321-F324 PolarHBondContact O-N 3.45Å; L321-L325 HydrophobicContact CD1-CG 4.36Å; L321-L325 HydrophobicContact CG-CD1 4.48Å; L321-L325 VanDerWaalsContact O-CG 3.28Å; L321-L325 WeakPolarHBondContact O-CG 3.32Å; L321-L325 PolarHBondContact O-N 2.88Å; L321-I400 HydrophobicContact CD1-CD1 3.91Å
322	I	93	Very high	84.9	Confident	89 Å²	89	42.2 Å²	42.2	46%	0.456	21%	0.207	S	C	.	.	H	α-helix	trans	-60.2	-48.2	177	-67.6	166.7	0	0	0	110.6	I318 I319 F324 L325 L326	I318-I322 HydrophobicContact CG2-CD1 3.98Å; I318-I322 WeakPolarHBondContact O-CG1 3.17Å; I318-I322 PolarHBondContact O-N 2.95Å; I319-I322 PolarHBondContact O-N 2.9Å; I322-F324 VanDerWaalsContact C-N 3.28Å; I322-F324 PolarHBondContact O-N 2.9Å; I322-L325 PolarHBondContact O-N 3.09Å; I322-L326 HydrophobicContact CG2-CD1 4.14Å; I322-L326 HydrophobicContact CG2-CG 4.48Å; I322-L326 WeakPolarHBondContact O-CG 3.45Å; I322-L326 PolarHBondContact O-N 3.21Å
323	L	92.4	Very high	86.4	Confident	40 Å²	40	40.8 Å²	40.8	21%	0.209	21%	0.208	C	C	.	.	H	α-helix	trans	-62.4	-37.1	178.7	-69.9	168.4	0	0	0	112	Q167 Y270 Y273 I319 G320 L321 C327	Q167-L323 VanDerWaalsContact NE2-C 3.33Å; Q167-L323 PolarHBondContact NE2-O 2.67Å; Y270-L323 HydrophobicContact CD2-CD1 4.33Å; Y270-L323 HydrophobicContact CE2-CD1 4.01Å; Y273-L323 HydrophobicContact CD1-CD1 3.6Å; Y273-L323 HydrophobicContact CD2-CD1 4.38Å; Y273-L323 HydrophobicContact CE1-CD1 3.38Å; Y273-L323 HydrophobicContact CE2-CD1 4.22Å; Y273-L323 HydrophobicContact CG-CD1 4.11Å; I319-L323 HydrophobicContact CG2-CD1 3.9Å; I319-L323 HydrophobicContact CG2-CG 4.39Å; I319-L323 VanDerWaalsContact O-CG 3.31Å; I319-L323 WeakPolarHBondContact O-CG 3.32Å; I319-L323 PolarHBondContact O-N 3.01Å; G320-L323 PolarHBondContact O-N 3.09Å; L321-L323 PolarHBondContact O-N 2.92Å; L323-C327 WeakPolarHBondContact O-CB 3.36Å; L323-C327 PolarHBondContact O-N 2.98Å
324	F	93.6	Very high	87	Confident	2 Å²	2	38.3 Å²	38.3	1%	0.009	20%	0.199	C	C	.	.	H	α-helix	trans	-61.3	-48.3	172.5	167.1	-89.8	0	0	0	111.9	L46 V50 F163 G320 L321 I322 L326 C327 V328 A396 Y399 I400	L46-F324 HydrophobicContact CD2-CZ 3.74Å; L46-F324 HydrophobicContact CG-CZ 4.23Å; V50-F324 HydrophobicContact CG2-CE1 4.08Å; V50-F324 HydrophobicContact CG2-CZ 4.44Å; F163-F324 AromaticContact CE1-CD2 3.62Å; F163-F324 HydrophobicContact CE1-CD2 3.62Å; F163-F324 HydrophobicContact CE1-CE2 4.12Å; F163-F324 AromaticContact CZ-CD2 3.76Å; F163-F324 HydrophobicContact CZ-CD2 3.76Å; F163-F324 AromaticContact CZ-CE2 3.91Å; F163-F324 HydrophobicContact CZ-CE2 3.91Å; G320-F324 VanDerWaalsContact O-CB 3.3Å; G320-F324 WeakPolarHBondContact O-CB 3.4Å; G320-F324 PolarHBondContact O-N 2.95Å; L321-F324 HydrophobicContact CD1-CD1 4.3Å; L321-F324 WeakPolarHBondContact O-CB 3.44Å; L321-F324 PolarHBondContact O-N 3.45Å; I322-F324 VanDerWaalsContact C-N 3.28Å; I322-F324 PolarHBondContact O-N 2.9Å; F324-L326 PolarHBondContact O-N 3.05Å; F324-C327 WeakPolarHBondContact O-CB 3.27Å; F324-C327 PolarHBondContact O-N 3.13Å; F324-V328 HydrophobicContact CD1-CG2 4.34Å; F324-V328 HydrophobicContact CD2-CG2 4.18Å; F324-V328 HydrophobicContact CE1-CG2 3.98Å; F324-V328 HydrophobicContact CE2-CG2 3.82Å; F324-V328 HydrophobicContact CG-CG2 4.44Å; F324-V328 HydrophobicContact CZ-CG2 3.71Å; F324-V328 WeakPolarHBondContact O-CG2 3.46Å; F324-V328 PolarHBondContact O-N 3.05Å; F324-A396 HydrophobicContact CE2-CB 3.69Å; F324-A396 HydrophobicContact CZ-CB 4.18Å; F324-Y399 HydrophobicContact CB-CD1 4.44Å; F324-Y399 HydrophobicContact CB-CE1 3.95Å; F324-Y399 AromaticContact CD2-CD1 3.65Å; F324-Y399 HydrophobicContact CD2-CD1 3.65Å; F324-Y399 HydrophobicContact CD2-CE1 4.03Å; F324-Y399 HydrophobicContact CE2-CD1 4.32Å; F324-Y399 HydrophobicContact CG-CD1 4.4Å; F324-Y399 HydrophobicContact CG-CE1 4.39Å; F324-I400 HydrophobicContact CB-CD1 4.1Å; F324-I400 HydrophobicContact CD1-CD1 3.55Å; F324-I400 HydrophobicContact CD1-CG1 3.98Å; F324-I400 HydrophobicContact CD2-CD1 3.66Å; F324-I400 HydrophobicContact CD2-CG1 3.73Å; F324-I400 HydrophobicContact CE1-CD1 3.76Å; F324-I400 HydrophobicContact CE1-CG1 3.65Å; F324-I400 HydrophobicContact CE2-CD1 3.83Å; F324-I400 HydrophobicContact CE2-CG1 3.36Å; F324-I400 HydrophobicContact CG-CD1 3.49Å; F324-I400 VanDerWaalsContact CG-CD1 3.49Å; F324-I400 HydrophobicContact CG-CG1 4.01Å; F324-I400 HydrophobicContact CZ-CD1 3.89Å; F324-I400 HydrophobicContact CZ-CG1 3.31Å
325	L	93.3	Very high	86.7	Confident	47 Å²	47	37.8 Å²	37.8	25%	0.246	20%	0.197	C	C	.	.	H	α-helix	trans	-60.8	-48.3	-180	-66	177.1	0	0	0	110.9	L47 L321 I322 C327 V328 F329	L47-L325 HydrophobicContact CD1-CD1 4.49Å; L47-L325 HydrophobicContact CD1-CD2 3.27Å; L47-L325 HydrophobicContact CD2-CD2 4.44Å; L47-L325 HydrophobicContact CG-CD2 4.35Å; L321-L325 HydrophobicContact CD1-CG 4.36Å; L321-L325 HydrophobicContact CG-CD1 4.48Å; L321-L325 VanDerWaalsContact O-CG 3.28Å; L321-L325 WeakPolarHBondContact O-CG 3.32Å; L321-L325 PolarHBondContact O-N 2.88Å; I322-L325 PolarHBondContact O-N 3.09Å; L325-C327 VanDerWaalsContact C-N 3.29Å; L325-C327 PolarHBondContact O-N 2.83Å; L325-V328 PolarHBondContact O-N 3.34Å; L325-F329 HydrophobicContact CB-CD2 4.49Å; L325-F329 WeakPolarHBondContact O-CD2 3.38Å; L325-F329 PolarHBondContact O-N 3.43Å
326	L	92.5	Very high	85.5	Confident	113 Å²	113	37.5 Å²	37.5	59%	0.592	19%	0.194	S	C	*	.	H	α-helix	trans	-57.6	-44.2	177	-67	176.5	0	0	0	111.3	I322 F324 Y330	I322-L326 HydrophobicContact CG2-CD1 4.14Å; I322-L326 HydrophobicContact CG2-CG 4.48Å; I322-L326 WeakPolarHBondContact O-CG 3.45Å; I322-L326 PolarHBondContact O-N 3.21Å; F324-L326 PolarHBondContact O-N 3.05Å; L326-Y330 WeakPolarHBondContact O-CB 3.45Å; L326-Y330 PolarHBondContact O-N 2.95Å
327	C	91.8	Very high	83.9	Confident	11 Å²	11	43 Å²	43	7%	0.074	22%	0.223	C	C	.	.	H	α-helix	trans	-61.9	-48.5	177.8	-179	0	0	0	0	112.6	Q167 L170 L323 F324 L325 Y330 S331	Q167-C327 HydrophobicContact CG-CB 4.16Å; L170-C327 WeakPolarHBondContact CD1-SG 3.34Å; L323-C327 WeakPolarHBondContact O-CB 3.36Å; L323-C327 PolarHBondContact O-N 2.98Å; F324-C327 WeakPolarHBondContact O-CB 3.27Å; F324-C327 PolarHBondContact O-N 3.13Å; L325-C327 VanDerWaalsContact C-N 3.29Å; L325-C327 PolarHBondContact O-N 2.83Å; C327-Y330 PolarHBondContact O-N 3.24Å; C327-S331 WeakPolarHBondContact O-CB 3.42Å; C327-S331 PolarHBondContact O-N 3.15Å
328	V	90.6	Very high	82.2	Confident	11 Å²	11	45.5 Å²	45.5	7%	0.067	24%	0.235	C	C	.	.	H	α-helix	trans	-64.7	-43.3	-179.2	170.6	0	0	0	0	111.2	A43 F163 F324 L325 S332	A43-V328 HydrophobicContact CB-CG1 3.6Å; F163-V328 HydrophobicContact CZ-CG2 4.37Å; F324-V328 HydrophobicContact CD1-CG2 4.34Å; F324-V328 HydrophobicContact CD2-CG2 4.18Å; F324-V328 HydrophobicContact CE1-CG2 3.98Å; F324-V328 HydrophobicContact CE2-CG2 3.82Å; F324-V328 HydrophobicContact CG-CG2 4.44Å; F324-V328 HydrophobicContact CZ-CG2 3.71Å; F324-V328 WeakPolarHBondContact O-CG2 3.46Å; F324-V328 PolarHBondContact O-N 3.05Å; L325-V328 PolarHBondContact O-N 3.34Å; V328-S332 WeakPolarHBondContact O-CB 2.89Å; V328-S332 PolarHBondContact O-N 3.34Å; V328-S332 PolarHBondContact O-OG 2.83Å
329	F	90.1	Very high	80.1	Confident	66 Å²	66	44.9 Å²	44.9	29%	0.289	24%	0.237	S	C	.	.	H	α-helix	trans	-65.8	-43.5	175.2	-78.7	-63.2	0	0	0	111.7	L40 L44 L47 L325 S331 S332 I333	L40-F329 HydrophobicContact CD2-CD1 4.25Å; L44-F329 HydrophobicContact CD2-CE1 4.06Å; L44-F329 HydrophobicContact CD2-CZ 4.06Å; L47-F329 HydrophobicContact CD2-CE2 4.27Å; L47-F329 HydrophobicContact CD2-CZ 4Å; L325-F329 HydrophobicContact CB-CD2 4.49Å; L325-F329 WeakPolarHBondContact O-CD2 3.38Å; L325-F329 PolarHBondContact O-N 3.43Å; F329-S331 PolarHBondContact O-N 3.39Å; F329-S332 PolarHBondContact O-N 3.46Å; F329-I333 WeakPolarHBondContact O-CG1 3.11Å; F329-I333 PolarHBondContact O-N 3.21Å
330	Y	88.9	Confident	77.8	Confident	44 Å²	44	45.5 Å²	45.5	17%	0.173	24%	0.238	C	C	.	.	H	α-helix	trans	-60.6	-46.6	178.4	-178.5	-102.3	0	0	0	111.8	L170 D173 F174 L326 C327 S332 I333 R334	L170-Y330 HydrophobicContact CB-CD1 4.34Å; L170-Y330 HydrophobicContact CD2-CD1 4.25Å; L170-Y330 HydrophobicContact CD2-CE1 4.34Å; D173-Y330 WeakPolarHBondContact OD2-CE1 3.44Å; D173-Y330 PolarHBondContact OD2-OH 3.04Å; F174-Y330 WeakPolarHBondContact CA-OH 3.37Å; F174-Y330 HydrophobicContact CB-CE1 4.07Å; F174-Y330 HydrophobicContact CB-CE2 4.06Å; F174-Y330 HydrophobicContact CD2-CD2 4.13Å; F174-Y330 AromaticContact CD2-CE2 3.71Å; F174-Y330 HydrophobicContact CD2-CE2 3.71Å; F174-Y330 HydrophobicContact CG-CE2 4.37Å; F174-Y330 PolarHBondContact N-OH 2.99Å; L326-Y330 WeakPolarHBondContact O-CB 3.45Å; L326-Y330 PolarHBondContact O-N 2.95Å; C327-Y330 PolarHBondContact O-N 3.24Å; Y330-S332 VanDerWaalsContact C-N 3.32Å; Y330-S332 PolarHBondContact O-N 3.48Å; Y330-I333 PolarHBondContact O-N 3.23Å; Y330-R334 HydrophobicContact CE1-CB 4.37Å; Y330-R334 HydrophobicContact CE2-CB 4.4Å; Y330-R334 WeakPolarHBondContact O-CB 3.46Å; Y330-R334 PolarHBondContact O-N 3.44Å; Y330-R334 WeakPolarHBondContact OH-CD 3.38Å; Y330-R334 PolarHBondContact OH-NE 2.95Å; Y330-R334 PolarHBondContact OH-NH1 2.93Å
331	S	86.5	Confident	75.7	Confident	10 Å²	10	46.2 Å²	46.2	7%	0.07	24%	0.242	C	C	.	.	H	α-helix	trans	-60.8	-40.6	173.9	175.9	0	0	0	0	112.1	R39 C327 F329 I333 T335	R39-S331 PolarHBondContact NH1-O 3.44Å; C327-S331 WeakPolarHBondContact O-CB 3.42Å; C327-S331 PolarHBondContact O-N 3.15Å; F329-S331 PolarHBondContact O-N 3.39Å; S331-I333 PolarHBondContact O-N 2.84Å; S331-T335 WeakPolarHBondContact O-CB 3.45Å; S331-T335 PolarHBondContact O-N 3.47Å; S331-T335 PolarHBondContact O-OG1 3.45Å; S331-T335 VanDerWaalsContact O-OG1 3.11Å
332	S	86	Confident	73.4	Confident	1 Å²	1	46.4 Å²	46.4	1%	0.007	24%	0.243	C	C	.	.	H	α-helix	trans	-69	-21.1	179.2	-58.1	0	0	0	0	113.7	R39 A43 V328 F329 Y330	R39-S332 PolarHBondContact NH1-O 3.08Å; R39-S332 PolarHBondContact NH2-O 3.46Å; R39-S332 VanDerWaalsContact NH2-O 3.1Å; A43-S332 WeakPolarHBondContact CB-OG 3.23Å; V328-S332 WeakPolarHBondContact O-CB 2.89Å; V328-S332 PolarHBondContact O-N 3.34Å; V328-S332 PolarHBondContact O-OG 2.83Å; F329-S332 PolarHBondContact O-N 3.46Å; Y330-S332 VanDerWaalsContact C-N 3.32Å; Y330-S332 PolarHBondContact O-N 3.48Å
333	I	83.1	Confident	71.1	Confident	98 Å²	98	47.9 Å²	47.9	50%	0.503	25%	0.246	S	C	.	.	H	α-helix	trans	-94	-58	175.5	-64	166	0	0	0	109.3	R39 L40 F329 Y330 S331 T335 S336	R39-I333 PolarHBondContact NH2-O 3.49Å; L40-I333 HydrophobicContact CD2-CG1 4.33Å; F329-I333 WeakPolarHBondContact O-CG1 3.11Å; F329-I333 PolarHBondContact O-N 3.21Å; Y330-I333 PolarHBondContact O-N 3.23Å; S331-I333 PolarHBondContact O-N 2.84Å; I333-T335 PolarHBondContact O-N 3.22Å; I333-S336 PolarHBondContact O-OG 3.22Å
334	R	74.8	Confident	68.6	Low	35 Å²	35	51.9 Å²	51.9	13%	0.132	27%	0.267	C	S	.	.	H	α-helix	trans	-71.6	-32.5	-166.3	-175.3	168.2	175.8	134.7	-6.8	115.5	D173 S177 Y330 S336 N337	D173-R334 VanDerWaalsContact CG-CZ 3.42Å; D173-R334 VanDerWaalsContact CG-NH2 3.3Å; D173-R334 IonicContact OD1-CZ 2.8Å; D173-R334 IonicContact OD1-NE 3.69Å; D173-R334 PolarHBondContact OD1-NE 2.94Å; D173-R334 IonicContact OD1-NH2 3.21Å; D173-R334 PolarHBondContact OD1-NH2 3.28Å; D173-R334 WeakPolarHBondContact OD2-CD 3.15Å; D173-R334 IonicContact OD2-CZ 3.83Å; D173-R334 IonicContact OD2-NE 2.82Å; D173-R334 PolarHBondContact OD2-NE 3.29Å; D173-R334 IonicContact OD2-NH1 2.86Å; D173-R334 IonicContact OD2-NH2 2.68Å; D173-R334 PolarHBondContact OD2-NH2 2.89Å; S177-R334 PolarHBondContact OG-NH1 3.02Å; S177-R334 PolarHBondContact OG-NH2 2.92Å; Y330-R334 HydrophobicContact CE1-CB 4.37Å; Y330-R334 HydrophobicContact CE2-CB 4.4Å; Y330-R334 WeakPolarHBondContact O-CB 3.46Å; Y330-R334 PolarHBondContact O-N 3.44Å; Y330-R334 WeakPolarHBondContact OH-CD 3.38Å; Y330-R334 PolarHBondContact OH-NE 2.95Å; Y330-R334 PolarHBondContact OH-NH1 2.93Å; R334-S336 PolarHBondContact O-N 3.01Å; R334-N337 PolarHBondContact O-N 3.19Å
335	T	62.8	Low	66	Low	18 Å²	18	53.3 Å²	53.3	11%	0.11	28%	0.277	C	S	.	.	T	Hydrogen-bonded Turn	trans	-60.1	-13.4	-176.5	-61	0	0	0	0	113.7	R39 S331 I333 Y384	R39-T335 VanDerWaalsContact NH1-CB 3.33Å; S331-T335 WeakPolarHBondContact O-CB 3.45Å; S331-T335 PolarHBondContact O-N 3.47Å; S331-T335 PolarHBondContact O-OG1 3.45Å; S331-T335 VanDerWaalsContact O-OG1 3.11Å; I333-T335 PolarHBondContact O-N 3.22Å; T335-Y384 HydrophobicContact CG2-CG 4.13Å
336	S	51.7	Low	63.4	Low	23 Å²	23	59.6 Å²	59.6	16%	0.161	31%	0.31	C	S	.	.	T	Hydrogen-bonded Turn	trans	-80.2	-16.6	170.8	50.8	0	0	0	0	115.1	T36 R39 I333 R334	T36-S336 PolarHBondContact OG1-OG 3Å; R39-S336 PolarHBondContact NH2-OG 2.86Å; I333-S336 PolarHBondContact O-OG 3.22Å; R334-S336 PolarHBondContact O-N 3.01Å
337	N	48.9	Very low	60.8	Low	122 Å²	122	56 Å²	56	65%	0.652	29%	0.292	S	S	*	.	T	Hydrogen-bonded Turn	trans	-113.6	-5	-163.7	-78.7	35.5	0	0	0	114.6	R334	R334-N337 PolarHBondContact O-N 3.19Å
338	N	47.7	Very low	58	Low	63 Å²	63	60 Å²	60	34%	0.337	32%	0.321	S	S	.	.			trans	-145.7	116.1	-177.4	-100.5	-56.6	0	0	0	113.7	Q340 V341	N338-Q340 PolarHBondContact O-N 2.93Å; N338-V341 HydrophobicContact CB-CG2 4.43Å; N338-V341 PolarHBondContact O-N 3.45Å
339	S	41.4	Very low	55.6	Low	60 Å²	60	65.3 Å²	65.3	42%	0.42	35%	0.348	S	S	.	.	H	α-helix	trans	-61.2	-20.1	170.2	58.7	0	0	0	0	113.2	V341 N342 K343	S339-V341 VanDerWaalsContact C-N 3.32Å; S339-V341 PolarHBondContact O-N 2.86Å; S339-N342 WeakPolarHBondContact O-CB 3.39Å; S339-N342 PolarHBondContact O-N 3.22Å; S339-K343 PolarHBondContact O-N 3.22Å
340	Q	41.8	Very low	53.3	Low	80 Å²	80	68.6 Å²	68.6	37%	0.374	37%	0.365	S	S	.	.	H	α-helix	trans	-66.1	-29	-179	-65.8	-168.2	-7.9	0	0	113.5	N338 K343 D453	N338-Q340 PolarHBondContact O-N 2.93Å; Q340-K343 WeakPolarHBondContact O-CB 3.45Å; Q340-K343 PolarHBondContact O-N 2.64Å; Q340-D453 PolarHBondContact NE2-O 3.29Å
341	V	47.1	Very low	50.9	Low	15 Å²	15	70 Å²	70	9%	0.091	38%	0.381	C	S	.	.	H	α-helix	trans	-75.9	-34.4	176.2	-150.6	0	0	0	0	111	N338 S339 K343 L344 T345	N338-V341 HydrophobicContact CB-CG2 4.43Å; N338-V341 PolarHBondContact O-N 3.45Å; S339-V341 VanDerWaalsContact C-N 3.32Å; S339-V341 PolarHBondContact O-N 2.86Å; V341-K343 VanDerWaalsContact C-N 3.25Å; V341-K343 PolarHBondContact O-N 3.11Å; V341-L344 PolarHBondContact O-N 2.74Å; V341-T345 WeakPolarHBondContact O-CG2 3.26Å; V341-T345 PolarHBondContact O-N 2.76Å; V341-T345 PolarHBondContact O-OG1 3.38Å
342	N	44.3	Very low	48.7	Very low	26 Å²	26	72.9 Å²	72.9	14%	0.139	40%	0.398	C	S	.	.	H	α-helix	trans	-62.2	-33.1	171.9	-80.9	-16	0	0	0	111.8	S339 L344 T345 T347 T383	S339-N342 WeakPolarHBondContact O-CB 3.39Å; S339-N342 PolarHBondContact O-N 3.22Å; N342-L344 PolarHBondContact O-N 3.3Å; N342-T345 WeakPolarHBondContact CA-OG1 3.4Å; N342-T345 PolarHBondContact O-N 2.74Å; N342-T345 PolarHBondContact O-OG1 2.92Å; N342-T347 PolarHBondContact O-OG1 3.21Å; N342-T383 PolarHBondContact ND2-O 3.32Å
343	K	43.3	Very low	46.3	Very low	120 Å²	120	80 Å²	80	52%	0.522	44%	0.435	S	S	.	.	H	α-helix	trans	-65.7	-22	173.4	-77.9	-176.9	175.7	176.4	0	113.5	S339 Q340 V341	S339-K343 PolarHBondContact O-N 3.22Å; Q340-K343 WeakPolarHBondContact O-CB 3.45Å; Q340-K343 PolarHBondContact O-N 2.64Å; V341-K343 VanDerWaalsContact C-N 3.25Å; V341-K343 PolarHBondContact O-N 3.11Å
344	L	41.5	Very low	44.3	Very low	124 Å²	124	81.2 Å²	81.2	65%	0.649	44%	0.441	S	S	*	.	H	α-helix	trans	-95.9	-16.9	178.3	-80.6	147.4	0	0	0	113.2	V341 N342	V341-L344 PolarHBondContact O-N 2.74Å; N342-L344 PolarHBondContact O-N 3.3Å
345	T	38.8	Very low	42.8	Very low	33 Å²	33	89 Å²	89	20%	0.202	48%	0.479	C	S	.	.	T	Hydrogen-bonded Turn	trans	-99.3	23.8	-174.1	54.1	0	0	0	0	115.1	V341 N342 T347 F388	V341-T345 WeakPolarHBondContact O-CG2 3.26Å; V341-T345 PolarHBondContact O-N 2.76Å; V341-T345 PolarHBondContact O-OG1 3.38Å; N342-T345 WeakPolarHBondContact CA-OG1 3.4Å; N342-T345 PolarHBondContact O-N 2.74Å; N342-T345 PolarHBondContact O-OG1 2.92Å; T345-T347 PolarHBondContact O-N 3.5Å; T345-T347 VanDerWaalsContact O-N 3.15Å; T345-F388 HydrophobicContact CG2-CD1 4.46Å; T345-F388 HydrophobicContact CG2-CE1 3.52Å; T345-F388 HydrophobicContact CG2-CZ 3.64Å
346	L	37.8	Very low	41.6	Very low	179 Å²	179	96.2 Å²	96.2	94%	0.937	52%	0.517	S	S	*	.	T	Hydrogen-bonded Turn	trans	55.3	30.1	178.7	-72.2	163.9	0	0	0	113.8
347	T	37	Very low	40.5	Very low	37 Å²	37	98.2 Å²	98.2	23%	0.227	54%	0.541	C	S	.	.			trans	-95.4	109.3	169.3	52.7	0	0	0	0	108.8	N342 T345	N342-T347 PolarHBondContact O-OG1 3.21Å; T345-T347 PolarHBondContact O-N 3.5Å; T345-T347 VanDerWaalsContact O-N 3.15Å
348	S	34.8	Very low	39.5	Very low	96 Å²	96	95.3 Å²	95.3	67%	0.671	54%	0.541	S	S	*	.			trans	-43.8	139.5	178.7	45.8	0	0	0	0	114.5	E350	S348-E350 PolarHBondContact O-N 3.39Å
349	D	39.5	Very low	38.6	Very low	121 Å²	121	97.7 Å²	97.7	65%	0.647	57%	0.569	S	S	*	*	T	Hydrogen-bonded Turn	trans	-50.9	18.1	-179.6	-70.5	-47.2	0	0	0	118.2
350	E	41.3	Very low	38	Very low	136 Å²	136	106.1 Å²	106.1	64%	0.636	59%	0.592	S	S	*	*	T	Hydrogen-bonded Turn	trans	-93.9	-9.2	-175.6	-152.4	-179.3	106.6	0	0	113.8	K112 S348	K112-E350 IonicContact NZ-OE1 2.77Å; K112-E350 PolarHBondContact NZ-OE1 3.07Å; S348-E350 PolarHBondContact O-N 3.39Å
351	S	39.5	Very low	37.4	Very low	73 Å²	73	108 Å²	108	51%	0.51	61%	0.614	S	S	.	*	S	Bend	trans	-99	-5	-178.2	40.9	0	0	0	0	114.4
352	T	39.4	Very low	36.6	Very low	71 Å²	71	115.1 Å²	115.1	44%	0.436	65%	0.651	S	S	.	*	S	Bend	trans	-105	12.3	-174.9	47.1	0	0	0	0	114.4
353	L	35.6	Very low	35.9	Very low	149 Å²	149	116.1 Å²	116.1	78%	0.78	67%	0.667	S	S	*	*	S	Bend	trans	-100.3	13.7	-178.1	-77.9	171.1	0	0	0	115
354	I	41.2	Very low	35.2	Very low	124 Å²	124	116 Å²	116	64%	0.636	68%	0.682	S	S	*	*	S	Bend	trans	-115.4	-10.5	-174.7	-55.4	179.6	0	0	0	113.6	D356	I354-D356 VanDerWaalsContact C-N 3.34Å; I354-D356 PolarHBondContact O-N 3.03Å
355	E	44.3	Very low	34.8	Very low	198 Å²	198	118.7 Å²	118.7	93%	0.925	70%	0.696	S	S	*	*	T	Hydrogen-bonded Turn	trans	-81.2	-6.2	-176.4	-131.9	174.5	150.3	0	0	115.1
356	D	36.1	Very low	34.5	Very low	170 Å²	170	126.4 Å²	126.4	91%	0.909	73%	0.73	S	S	*	*	T	Hydrogen-bonded Turn	trans	-104.5	18.8	178.4	-150.5	17.9	0	0	0	113.3	I354	I354-D356 VanDerWaalsContact C-N 3.34Å; I354-D356 PolarHBondContact O-N 3.03Å
357	G	29.6	Very low	34.3	Very low	65 Å²	65	125.5 Å²	125.5	67%	0.67	73%	0.726	S	S	*	*	S	Bend	trans	-111.9	49.4	-168.3	0	0	0	0	0	115.6
358	G	28	Very low	34.2	Very low	62 Å²	62	127.5 Å²	127.5	64%	0.639	75%	0.754	S	S	*	*			trans	70.2	113.1	155	0	0	0	0	0	117.3	R360	G358-R360 PolarHBondContact O-N 3.27Å
359	A	28.5	Very low	34.3	Very low	113 Å²	113	130.1 Å²	130.1	93%	0.934	76%	0.76	S	S	*	*			trans	-46.2	94.9	156.1	0	0	0	0	0	111.4
360	R	29.3	Very low	34.5	Very low	237 Å²	237	130.1 Å²	130.1	89%	0.894	76%	0.76	S	S	*	*			trans	-93.4	100	164.5	-84.7	-175.7	169.4	166.1	-0.6	108.3	G358 D362	G358-R360 PolarHBondContact O-N 3.27Å; R360-D362 PolarHBondContact O-N 2.95Å; R360-D362 VanDerWaalsContact O-N 3.11Å
361	S	27.9	Very low	35	Very low	119 Å²	119	129.2 Å²	129.2	83%	0.832	76%	0.764	S	S	*	*			trans	-35	105.6	153.5	167.5	0	0	0	0	111.3
362	D	31.8	Very low	35.5	Very low	165 Å²	165	131.8 Å²	131.8	88%	0.882	77%	0.767	S	S	*	*			trans	-110.1	110.3	152.6	-151.7	12.6	0	0	0	107.5	R360	R360-D362 PolarHBondContact O-N 2.95Å; R360-D362 VanDerWaalsContact O-N 3.11Å
363	G	29.4	Very low	36.3	Very low	46 Å²	46	134.5 Å²	134.5	47%	0.474	77%	0.77	S	S	.	*			trans	-80.3	163.2	-178	0	0	0	0	0	111.5
364	S	27.9	Very low	37.5	Very low	118 Å²	118	127.8 Å²	127.8	83%	0.825	74%	0.735	S	S	*	*			trans	65.9	96.6	163	63	0	0	0	0	116.6
365	L	32.7	Very low	38.8	Very low	180 Å²	180	126.3 Å²	126.3	94%	0.942	73%	0.732	S	S	*	*				-153.6	92.2	120.1	-90.6	172.1	0	0	0	107.2	D367	L365-D367 PolarHBondContact O-N 2.71Å
366	E	33	Very low	40.3	Very low	196 Å²	196	119.7 Å²	119.7	92%	0.916	70%	0.703	S	S	*	*			trans	-67.7	114.8	159.7	-69.1	174.6	117	0	0	108.1
367	D	34.5	Very low	42.2	Very low	160 Å²	160	113.8 Å²	113.8	86%	0.856	67%	0.672	S	S	*	*			trans	-165.8	98.3	139.6	-147.8	7.4	0	0	0	112.5	L365 D369	L365-D367 PolarHBondContact O-N 2.71Å; D367-D369 PolarHBondContact O-N 2.68Å; D367-D369 VanDerWaalsContact O-N 3.09Å
368	G	33.6	Very low	44.6	Very low	79 Å²	79	110.7 Å²	110.7	81%	0.814	64%	0.64	S	S	*	*	S	Bend		77.6	-16.5	115.9	0	0	0	0	0	124.6
369	D	37.6	Very low	47	Very low	151 Å²	151	116.2 Å²	116.2	81%	0.807	64%	0.641	S	S	*	*			trans	-147	12	-171.5	-147.2	20.4	0	0	0	118.3	D367 V371	D367-D369 PolarHBondContact O-N 2.68Å; D367-D369 VanDerWaalsContact O-N 3.09Å; D369-V371 PolarHBondContact O-N 3.04Å
370	D	44.3	Very low	49.2	Very low	120 Å²	120	117.7 Å²	117.7	64%	0.642	63%	0.633	S	S	*	*			trans	-94.7	35.3	-166.3	-107.4	-23	0	0	0	116.3	H372	D370-H372 VanDerWaalsContact C-N 3.26Å; D370-H372 PolarHBondContact O-N 3.5Å
371	V	50.4	Low	51.6	Low	118 Å²	118	108 Å²	108	72%	0.715	61%	0.607	S	S	*	*	T	Hydrogen-bonded Turn	trans	-73.2	-9.5	-172.8	-175.7	0	0	0	0	114.2	D369	D369-V371 PolarHBondContact O-N 3.04Å
372	H	50.4	Low	54.2	Low	126 Å²	126	103.5 Å²	103.5	58%	0.583	57%	0.574	S	S	*	*	T	Hydrogen-bonded Turn	trans	-136.1	22.8	-173.2	-68.1	-54.2	0	0	0	116	D370	D370-H372 VanDerWaalsContact C-N 3.26Å; D370-H372 PolarHBondContact O-N 3.5Å
373	R	56	Low	56.5	Low	129 Å²	129	97.6 Å²	97.6	49%	0.487	54%	0.544	S	S	.	.	P	Polyproline II helix	trans	-92.5	122.6	178.4	-154.1	170.5	-176.5	133.6	-0.6	110.9
374	A	61.3	Low	59	Low	7 Å²	7	95.6 Å²	95.6	6%	0.058	52%	0.523	C	S	.	.	P	Polyproline II helix	trans	-57.7	142.1	169.2	0	0	0	0	0	109.6	L24 G32	L24-A374 HydrophobicContact CD2-CB 4.09Å; L24-A374 WeakPolarHBondContact CD2-O 3.31Å; G32-A374 WeakPolarHBondContact O-CA 3.49Å; G32-A374 VanDerWaalsContact O-CB 3.32Å; G32-A374 WeakPolarHBondContact O-CB 3.32Å
375	V	68.7	Low	61.8	Low	93 Å²	93	92 Å²	92	56%	0.564	50%	0.497	S	S	*	.	B	Isolated β-bridge	trans	-91	128.8	-177.9	-178.9	0	0	0	0	108.8	N34 N377	N34-V375 PolarHBondContact N-O 3.17Å; V375-N377 PolarHBondContact O-N 2.9Å
376	D	74.5	Confident	64.5	Low	60 Å²	60	83.4 Å²	83.4	32%	0.321	45%	0.452	S	S	.	.			trans	-78.2	98.8	170.8	-174.5	13.9	0	0	0	109.6	S114 E378	S114-D376 PolarHBondContact OG-OD1 3.41Å; S114-D376 PolarHBondContact OG-OD2 3.19Å; D376-E378 VanDerWaalsContact C-N 3.35Å; D376-E378 PolarHBondContact OD1-N 2.99Å
377	N	77.7	Confident	67.2	Low	46 Å²	46	75.1 Å²	75.1	25%	0.246	42%	0.416	C	S	.	.			trans	-91.9	9.6	-178.2	65.6	-51.7	0	0	0	113.4	S35 V375	S35-N377 PolarHBondContact N-OD1 3.43Å; S35-N377 PolarHBondContact OG-ND2 3.31Å; V375-N377 PolarHBondContact O-N 2.9Å
378	E	79.9	Confident	69.9	Low	0 Å²	0	70.2 Å²	70.2	0%	0	39%	0.387	C	S	.	.			trans	-120.6	14.8	-174.4	-65.3	-170.2	130.6	0	0	113.6	S35 S114 D376 G381 T383 Y386	S35-E378 WeakPolarHBondContact CB-OE1 3.23Å; S35-E378 WeakPolarHBondContact CB-OE2 3.38Å; S114-E378 WeakPolarHBondContact CB-O 3.28Å; S114-E378 PolarHBondContact N-O 2.92Å; S114-E378 PolarHBondContact OG-O 2.91Å; D376-E378 VanDerWaalsContact C-N 3.35Å; D376-E378 PolarHBondContact OD1-N 2.99Å; E378-G381 CarbonylContact C-O 3.54Å; E378-G381 VanDerWaalsContact CA-O 3.28Å; E378-G381 WeakPolarHBondContact CA-O 3.42Å; E378-G381 CarbonylContact O-C 3.6Å; E378-T383 HydrophobicContact CG-CG2 4.09Å; E378-T383 PolarHBondContact OE1-N 3.11Å; E378-T383 PolarHBondContact OE1-OG1 3.28Å; E378-Y386 WeakPolarHBondContact OE2-CE1 3.47Å; E378-Y386 VanDerWaalsContact OE2-CZ 3.32Å; E378-Y386 PolarHBondContact OE2-OH 3.22Å
379	R	76.6	Confident	72.6	Confident	178 Å²	178	66.6 Å²	66.6	67%	0.672	35%	0.349	S	S	*	.	S	Bend	trans	-64	-43.9	-177.3	-171.8	176.3	179.9	170.8	-1.5	112.9	S113 S114	S113-R379 PolarHBondContact OG-O 3.43Å; S114-R379 VanDerWaalsContact OG-CA 3.28Å; S114-R379 WeakPolarHBondContact OG-CA 3.38Å; S114-R379 PolarHBondContact OG-N 3.42Å
380	D	74.8	Confident	75.3	Confident	143 Å²	143	59.4 Å²	59.4	77%	0.765	31%	0.311	S	S	*	.	S	Bend	trans	-91	-14.5	-177.9	-59.1	-40.2	0	0	0	112.8
381	G	80.8	Confident	77.6	Confident	33 Å²	33	57.5 Å²	57.5	34%	0.34	30%	0.297	S	S	.	.	S	Bend	trans	178.1	144	177.9	0	0	0	0	0	111.4	K112 E378	K112-G381 WeakPolarHBondContact O-CA 3.3Å; E378-G381 CarbonylContact C-O 3.54Å; E378-G381 VanDerWaalsContact CA-O 3.28Å; E378-G381 WeakPolarHBondContact CA-O 3.42Å; E378-G381 CarbonylContact O-C 3.6Å
382	V	82.2	Confident	79.7	Confident	25 Å²	25	52.7 Å²	52.7	15%	0.152	27%	0.266	C	S	.	.			trans	-68.5	136	175.4	-66.7	0	0	0	0	111.1	V111 K112 Y384 Y386	V111-V382 HydrophobicContact CG1-CG1 4.4Å; K112-V382 PolarHBondContact O-N 2.87Å; V382-Y384 VanDerWaalsContact C-N 3.27Å; V382-Y384 WeakPolarHBondContact CB-O 3.28Å; V382-Y384 WeakPolarHBondContact CG2-O 3.34Å; V382-Y384 PolarHBondContact O-N 3.43Å; V382-Y386 HydrophobicContact CB-CE1 4.15Å; V382-Y386 HydrophobicContact CG1-CD1 4.34Å; V382-Y386 HydrophobicContact CG1-CE1 3.81Å; V382-Y386 HydrophobicContact CG1-CE2 4.02Å
383	T	79.7	Confident	81.8	Confident	41 Å²	41	47 Å²	47	25%	0.252	24%	0.241	S	C	.	.	S	Bend	trans	-73	-23.4	178.1	54.4	0	0	0	0	112.4	S35 N342 E378	S35-T383 PolarHBondContact OG-OG1 2.87Å; N342-T383 PolarHBondContact ND2-O 3.32Å; E378-T383 HydrophobicContact CG-CG2 4.09Å; E378-T383 PolarHBondContact OE1-N 3.11Å; E378-T383 PolarHBondContact OE1-OG1 3.28Å
384	Y	82	Confident	83.7	Confident	5 Å²	5	41.9 Å²	41.9	2%	0.02	22%	0.222	C	C	.	.	S	Bend	trans	-146	157.5	176.5	65.3	-86.1	0	0	0	111.2	R39 H122 T335 V382 Y386 F389	R39-Y384 HydrophobicContact CG-CE1 3.93Å; R39-Y384 HydrophobicContact CG-CE2 4.14Å; R39-Y384 WeakPolarHBondContact CG-OH 3.43Å; H122-Y384 AromaticContact NE2-CZ 3.85Å; H122-Y384 PolarHBondContact NE2-OH 2.87Å; T335-Y384 HydrophobicContact CG2-CG 4.13Å; V382-Y384 VanDerWaalsContact C-N 3.27Å; V382-Y384 WeakPolarHBondContact CB-O 3.28Å; V382-Y384 WeakPolarHBondContact CG2-O 3.34Å; V382-Y384 PolarHBondContact O-N 3.43Å; Y384-Y386 HydrophobicContact CD2-CD1 4Å; Y384-Y386 HydrophobicContact CE1-CD1 4.35Å; Y384-Y386 HydrophobicContact CE1-CE1 4.11Å; Y384-Y386 AromaticContact CE2-CD1 3.47Å; Y384-Y386 HydrophobicContact CE2-CD1 3.47Å; Y384-Y386 VanDerWaalsContact CE2-CD1 3.47Å; Y384-Y386 HydrophobicContact CE2-CE1 4.04Å; Y384-Y386 HydrophobicContact CE2-CG 4.47Å; Y384-Y386 AromaticContact CZ-CD1 3.65Å; Y384-Y386 AromaticContact CZ-CE1 3.72Å; Y384-Y386 PolarHBondContact O-N 3.23Å; Y384-Y386 VanDerWaalsContact O-N 3.09Å; Y384-F389 HydrophobicContact CD2-CB 3.76Å; Y384-F389 HydrophobicContact CD2-CG 4.37Å; Y384-F389 HydrophobicContact CE2-CB 3.64Å; Y384-F389 HydrophobicContact CE2-CD1 4.27Å; Y384-F389 HydrophobicContact CE2-CD2 4.5Å; Y384-F389 AromaticContact CE2-CG 3.89Å; Y384-F389 HydrophobicContact CE2-CG 3.89Å
385	S	86.4	Confident	85.3	Confident	41 Å²	41	42 Å²	42	29%	0.287	22%	0.221	S	C	.	.			trans	-69	109.1	172.7	173.7	0	0	0	0	110.5	S387 F388 F389	S385-S387 PolarHBondContact O-N 3.24Å; S385-F388 PolarHBondContact O-N 2.94Å; S385-F388 VanDerWaalsContact O-N 3.09Å; S385-F388 PolarHBondContact OG-N 2.97Å; S385-F389 PolarHBondContact O-N 3.16Å
386	Y	89.3	Confident	86.6	Confident	1 Å²	1	37.5 Å²	37.5	0%	0.004	19%	0.194	C	C	.	.	H	α-helix	trans	-55.9	-38.7	176.9	-68.8	-2.7	0	0	0	112.4	M108 V111 A119 H122 N123 E378 V382 Y384 H390	M108-Y386 HydrophobicContact SD-CD2 4.4Å; V111-Y386 HydrophobicContact CB-CD2 4.16Å; V111-Y386 HydrophobicContact CG1-CD2 3.77Å; V111-Y386 HydrophobicContact CG1-CE2 3.88Å; A119-Y386 HydrophobicContact CB-CE2 3.94Å; H122-Y386 HydrophobicContact CB-CD2 3.81Å; H122-Y386 HydrophobicContact CB-CE2 3.85Å; H122-Y386 AromaticContact CD2-CD2 3.81Å; H122-Y386 AromaticContact CD2-CE1 3.88Å; H122-Y386 AromaticContact CD2-CE2 3.69Å; H122-Y386 AromaticContact CD2-CG 3.95Å; H122-Y386 AromaticContact CD2-CZ 3.71Å; H122-Y386 AromaticContact CE1-CG 3.98Å; H122-Y386 AromaticContact CG-CD2 3.6Å; H122-Y386 AromaticContact CG-CE2 3.8Å; H122-Y386 AromaticContact CG-CG 3.95Å; H122-Y386 AromaticContact ND1-CD2 3.98Å; H122-Y386 AromaticContact ND1-CG 3.95Å; H122-Y386 AromaticContact NE2-CD1 3.86Å; N123-Y386 PolarHBondContact ND2-OH 3.44Å; E378-Y386 WeakPolarHBondContact OE2-CE1 3.47Å; E378-Y386 VanDerWaalsContact OE2-CZ 3.32Å; E378-Y386 PolarHBondContact OE2-OH 3.22Å; V382-Y386 HydrophobicContact CB-CE1 4.15Å; V382-Y386 HydrophobicContact CG1-CD1 4.34Å; V382-Y386 HydrophobicContact CG1-CE1 3.81Å; V382-Y386 HydrophobicContact CG1-CE2 4.02Å; Y384-Y386 HydrophobicContact CD2-CD1 4Å; Y384-Y386 HydrophobicContact CE1-CD1 4.35Å; Y384-Y386 HydrophobicContact CE1-CE1 4.11Å; Y384-Y386 AromaticContact CE2-CD1 3.47Å; Y384-Y386 HydrophobicContact CE2-CD1 3.47Å; Y384-Y386 VanDerWaalsContact CE2-CD1 3.47Å; Y384-Y386 HydrophobicContact CE2-CE1 4.04Å; Y384-Y386 HydrophobicContact CE2-CG 4.47Å; Y384-Y386 AromaticContact CZ-CD1 3.65Å; Y384-Y386 AromaticContact CZ-CE1 3.72Å; Y384-Y386 PolarHBondContact O-N 3.23Å; Y384-Y386 VanDerWaalsContact O-N 3.09Å; Y386-H390 PolarHBondContact O-CD2 2.83Å; Y386-H390 VanDerWaalsContact O-CD2 3.23Å; Y386-H390 PolarHBondContact O-N 2.99Å
387	S	90.9	Very high	87.6	Confident	22 Å²	22	34.8 Å²	34.8	15%	0.154	18%	0.18	C	C	.	.	H	α-helix	trans	-62.2	-47.9	175.7	178.4	0	0	0	0	111.2	S105 S385 F389 H390 F391	S105-S387 PolarHBondContact O-OG 3.42Å; S105-S387 VanDerWaalsContact O-OG 3.12Å; S105-S387 PolarHBondContact OG-O 2.93Å; S105-S387 PolarHBondContact OG-OG 2.81Å; S385-S387 PolarHBondContact O-N 3.24Å; S387-F389 VanDerWaalsContact C-N 3.34Å; S387-F389 PolarHBondContact O-N 3.46Å; S387-H390 PolarHBondContact O-N 3.29Å; S387-F391 WeakPolarHBondContact O-CB 3.47Å; S387-F391 PolarHBondContact O-N 3.43Å
388	F	89.9	Confident	88.5	Confident	56 Å²	56	32.7 Å²	32.7	25%	0.246	17%	0.168	C	C	.	.	H	α-helix	trans	-65.6	-39.7	-177.7	-176	-106.4	0	0	0	111.5	T345 S385 H390 F391 M392	T345-F388 HydrophobicContact CG2-CD1 4.46Å; T345-F388 HydrophobicContact CG2-CE1 3.52Å; T345-F388 HydrophobicContact CG2-CZ 3.64Å; S385-F388 PolarHBondContact O-N 2.94Å; S385-F388 VanDerWaalsContact O-N 3.09Å; S385-F388 PolarHBondContact OG-N 2.97Å; F388-H390 PolarHBondContact O-N 2.81Å; F388-F391 WeakPolarHBondContact O-CB 3.29Å; F388-F391 PolarHBondContact O-N 3.05Å; F388-M392 HydrophobicContact CD1-CE 3.81Å; F388-M392 HydrophobicContact CD1-CG 4.16Å; F388-M392 HydrophobicContact CD1-SD 4.05Å; F388-M392 HydrophobicContact CE1-CE 3.76Å; F388-M392 HydrophobicContact CE1-CG 3.77Å; F388-M392 HydrophobicContact CE1-SD 3.42Å; F388-M392 WeakPolarHBondContact CE1-SD 3.5Å; F388-M392 HydrophobicContact CE2-CG 4.49Å; F388-M392 HydrophobicContact CZ-CG 3.95Å; F388-M392 HydrophobicContact CZ-SD 3.99Å; F388-M392 WeakPolarHBondContact O-CG 3.47Å; F388-M392 PolarHBondContact O-N 2.75Å
389	F	91.5	Very high	89.2	Confident	4 Å²	4	33.1 Å²	33.1	2%	0.018	17%	0.17	C	C	.	.	H	α-helix	trans	-56.9	-49.4	174.4	174.1	-101.5	0	0	0	112.5	R39 Y42 Y384 S385 S387 F391 M392 L393	R39-F389 HydrophobicContact CB-CE1 4.44Å; R39-F389 HydrophobicContact CB-CE2 3.86Å; R39-F389 HydrophobicContact CB-CZ 3.71Å; R39-F389 HydrophobicContact CG-CD1 4.45Å; R39-F389 HydrophobicContact CG-CD2 4.03Å; R39-F389 HydrophobicContact CG-CE1 4.09Å; R39-F389 HydrophobicContact CG-CE2 3.65Å; R39-F389 HydrophobicContact CG-CG 4.41Å; R39-F389 HydrophobicContact CG-CZ 3.68Å; Y42-F389 AromaticContact CD2-CE1 3.82Å; Y42-F389 HydrophobicContact CD2-CE1 3.82Å; Y42-F389 HydrophobicContact CG-CE1 4.17Å; Y384-F389 HydrophobicContact CD2-CB 3.76Å; Y384-F389 HydrophobicContact CD2-CG 4.37Å; Y384-F389 HydrophobicContact CE2-CB 3.64Å; Y384-F389 HydrophobicContact CE2-CD1 4.27Å; Y384-F389 HydrophobicContact CE2-CD2 4.5Å; Y384-F389 AromaticContact CE2-CG 3.89Å; Y384-F389 HydrophobicContact CE2-CG 3.89Å; S385-F389 PolarHBondContact O-N 3.16Å; S387-F389 VanDerWaalsContact C-N 3.34Å; S387-F389 PolarHBondContact O-N 3.46Å; F389-F391 VanDerWaalsContact C-N 3.32Å; F389-F391 PolarHBondContact O-N 2.9Å; F389-M392 HydrophobicContact CD2-CE 4.38Å; F389-M392 WeakPolarHBondContact O-CB 3.28Å; F389-M392 PolarHBondContact O-N 2.99Å; F389-L393 HydrophobicContact CD1-CD1 4.26Å; F389-L393 HydrophobicContact CE1-CD1 3.54Å; F389-L393 HydrophobicContact CE1-CG 4.37Å; F389-L393 HydrophobicContact CE2-CD1 4.41Å; F389-L393 HydrophobicContact CZ-CD1 3.64Å; F389-L393 HydrophobicContact CZ-CG 4.24Å; F389-L393 PolarHBondContact O-N 3.2Å; F389-L393 VanDerWaalsContact O-N 3.12Å
390	H	93.8	Very high	90.1	Very high	0 Å²	0	24.8 Å²	24.8	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-65.6	-35.8	177	-78.5	-55.9	0	0	0	112.6	Y42 Y101 L104 H122 Y386 S387 F388 M392 L393 F394	Y42-H390 AromaticContact CD1-CE1 3.91Å; Y42-H390 AromaticContact CD2-CE1 3.85Å; Y42-H390 AromaticContact CE1-CE1 3.65Å; Y42-H390 AromaticContact CE2-CE1 3.59Å; Y42-H390 AromaticContact CE2-NE2 3.89Å; Y42-H390 AromaticContact CZ-CE1 3.49Å; Y42-H390 VanDerWaalsContact CZ-CE1 3.49Å; Y42-H390 AromaticContact CZ-NE2 3.89Å; Y101-H390 AromaticContact CD1-ND1 3.83Å; L104-H390 HydrophobicContact CB-CB 4.31Å; H122-H390 AromaticContact CE1-CD2 3.87Å; H122-H390 AromaticContact CE1-NE2 3.21Å; H122-H390 PolarHBondContact CE1-NE2 3.04Å; H122-H390 AromaticContact ND1-CD2 3.77Å; H122-H390 AromaticContact ND1-NE2 3.09Å; H122-H390 PolarHBondContact ND1-NE2 3.4Å; Y386-H390 PolarHBondContact O-CD2 2.83Å; Y386-H390 VanDerWaalsContact O-CD2 3.23Å; Y386-H390 PolarHBondContact O-N 2.99Å; S387-H390 PolarHBondContact O-N 3.29Å; F388-H390 PolarHBondContact O-N 2.81Å; H390-M392 VanDerWaalsContact C-N 3.34Å; H390-L393 PolarHBondContact O-N 2.74Å; H390-F394 PolarHBondContact O-N 3.08Å
391	F	93.8	Very high	90.9	Very high	79 Å²	79	18 Å²	18	35%	0.346	10%	0.102	S	C	.	.	H	α-helix	trans	-63.3	-39.4	173.4	-172.9	-107.5	0	0	0	112.3	S387 F388 F389 L393 F394 L395	S387-F391 WeakPolarHBondContact O-CB 3.47Å; S387-F391 PolarHBondContact O-N 3.43Å; F388-F391 WeakPolarHBondContact O-CB 3.29Å; F388-F391 PolarHBondContact O-N 3.05Å; F389-F391 VanDerWaalsContact C-N 3.32Å; F389-F391 PolarHBondContact O-N 2.9Å; F391-L393 VanDerWaalsContact C-N 3.34Å; F391-L393 PolarHBondContact O-N 3.26Å; F391-F394 AromaticContact CD2-CD1 3.96Å; F391-F394 HydrophobicContact CD2-CD1 3.96Å; F391-F394 AromaticContact CE2-CD1 3.85Å; F391-F394 HydrophobicContact CE2-CD1 3.85Å; F391-F394 HydrophobicContact CE2-CE1 4.07Å; F391-F394 WeakPolarHBondContact O-CB 3.48Å; F391-F394 PolarHBondContact O-N 2.92Å; F391-L395 HydrophobicContact CD1-CD1 4.08Å; F391-L395 HydrophobicContact CD1-CG 4.45Å; F391-L395 HydrophobicContact CE1-CD1 3.68Å; F391-L395 HydrophobicContact CE1-CD2 4.49Å; F391-L395 HydrophobicContact CE1-CG 4.13Å; F391-L395 HydrophobicContact CZ-CD1 4.28Å; F391-L395 HydrophobicContact CZ-CD2 4.28Å; F391-L395 HydrophobicContact CZ-CG 4.33Å; F391-L395 WeakPolarHBondContact O-CG 3.38Å; F391-L395 PolarHBondContact O-N 2.91Å
392	M	92.8	Very high	91.4	Very high	17 Å²	17	16.4 Å²	16.4	8%	0.084	9%	0.086	C	C	.	.	H	α-helix	trans	-61.4	-42.1	172.7	-69.7	-167	-71.5	0	0	111.6	I166 F388 F389 H390 F394 L395 A396	I166-M392 HydrophobicContact CD1-CG 4.21Å; I166-M392 HydrophobicContact CG2-SD 4.01Å; F388-M392 HydrophobicContact CD1-CE 3.81Å; F388-M392 HydrophobicContact CD1-CG 4.16Å; F388-M392 HydrophobicContact CD1-SD 4.05Å; F388-M392 HydrophobicContact CE1-CE 3.76Å; F388-M392 HydrophobicContact CE1-CG 3.77Å; F388-M392 HydrophobicContact CE1-SD 3.42Å; F388-M392 WeakPolarHBondContact CE1-SD 3.5Å; F388-M392 HydrophobicContact CE2-CG 4.49Å; F388-M392 HydrophobicContact CZ-CG 3.95Å; F388-M392 HydrophobicContact CZ-SD 3.99Å; F388-M392 WeakPolarHBondContact O-CG 3.47Å; F388-M392 PolarHBondContact O-N 2.75Å; F389-M392 HydrophobicContact CD2-CE 4.38Å; F389-M392 WeakPolarHBondContact O-CB 3.28Å; F389-M392 PolarHBondContact O-N 2.99Å; H390-M392 VanDerWaalsContact C-N 3.34Å; M392-F394 VanDerWaalsContact C-N 3.35Å; M392-L395 PolarHBondContact O-N 3.43Å; M392-A396 VanDerWaalsContact O-CB 3.29Å; M392-A396 WeakPolarHBondContact O-CB 3.44Å; M392-A396 PolarHBondContact O-N 3.11Å
393	L	94.7	Very high	91.8	Very high	8 Å²	8	15.6 Å²	15.6	4%	0.042	8%	0.081	C	C	.	.	H	α-helix	trans	-67.8	-33.1	176.2	-64	-179.5	0	0	0	112.8	L46 Y101 F389 H390 F391 A396 S397	L46-L393 HydrophobicContact CD2-CD2 3.87Å; Y101-L393 HydrophobicContact CD1-CB 3.62Å; Y101-L393 HydrophobicContact CD1-CD1 3.77Å; Y101-L393 HydrophobicContact CD1-CG 4.37Å; Y101-L393 HydrophobicContact CD2-CB 4.18Å; Y101-L393 HydrophobicContact CE1-CB 3.9Å; Y101-L393 HydrophobicContact CE1-CD1 3.41Å; Y101-L393 VanDerWaalsContact CE1-CD1 3.41Å; Y101-L393 HydrophobicContact CE1-CG 4.3Å; Y101-L393 HydrophobicContact CE2-CB 4.45Å; Y101-L393 HydrophobicContact CG-CB 3.78Å; F389-L393 HydrophobicContact CD1-CD1 4.26Å; F389-L393 HydrophobicContact CE1-CD1 3.54Å; F389-L393 HydrophobicContact CE1-CG 4.37Å; F389-L393 HydrophobicContact CE2-CD1 4.41Å; F389-L393 HydrophobicContact CZ-CD1 3.64Å; F389-L393 HydrophobicContact CZ-CG 4.24Å; F389-L393 PolarHBondContact O-N 3.2Å; F389-L393 VanDerWaalsContact O-N 3.12Å; H390-L393 PolarHBondContact O-N 2.74Å; F391-L393 VanDerWaalsContact C-N 3.34Å; F391-L393 PolarHBondContact O-N 3.26Å; L393-A396 WeakPolarHBondContact O-CB 3.42Å; L393-A396 PolarHBondContact O-N 3.36Å; L393-S397 PolarHBondContact O-N 3.46Å
394	F	96.3	Very high	92.2	Very high	21 Å²	21	14.2 Å²	14.2	9%	0.092	7%	0.072	C	C	.	.	H	α-helix	trans	-59.2	-51.3	168.9	160.8	-105.9	0	0	0	110.9	A98 L102 H390 F391 M392 A396 S397 L398	A98-F394 HydrophobicContact CB-CD2 3.77Å; A98-F394 HydrophobicContact CB-CE2 3.89Å; A98-F394 VanDerWaalsContact O-CD2 3.3Å; A98-F394 WeakPolarHBondContact O-CD2 3.24Å; L102-F394 HydrophobicContact CB-CD2 3.85Å; L102-F394 HydrophobicContact CB-CE2 4.21Å; L102-F394 HydrophobicContact CB-CG 4.27Å; L102-F394 HydrophobicContact CD1-CD1 4.42Å; L102-F394 HydrophobicContact CD1-CE1 4.5Å; L102-F394 HydrophobicContact CD1-CG 4.43Å; L102-F394 HydrophobicContact CD2-CE2 4.18Å; L102-F394 HydrophobicContact CD2-CZ 4.45Å; H390-F394 PolarHBondContact O-N 3.08Å; F391-F394 AromaticContact CD2-CD1 3.96Å; F391-F394 HydrophobicContact CD2-CD1 3.96Å; F391-F394 AromaticContact CE2-CD1 3.85Å; F391-F394 HydrophobicContact CE2-CD1 3.85Å; F391-F394 HydrophobicContact CE2-CE1 4.07Å; F391-F394 WeakPolarHBondContact O-CB 3.48Å; F391-F394 PolarHBondContact O-N 2.92Å; M392-F394 VanDerWaalsContact C-N 3.35Å; F394-A396 VanDerWaalsContact C-N 3.3Å; F394-A396 PolarHBondContact O-N 3.3Å; F394-S397 PolarHBondContact O-N 2.89Å; F394-S397 PolarHBondContact O-OG 3.49Å; F394-L398 HydrophobicContact CE1-CD1 3.96Å; F394-L398 HydrophobicContact CE2-CD1 3.98Å; F394-L398 HydrophobicContact CE2-CG 4.36Å; F394-L398 HydrophobicContact CZ-CD1 3.61Å; F394-L398 HydrophobicContact CZ-CG 4.46Å; F394-L398 PolarHBondContact O-N 3.42Å
395	L	96	Very high	92.4	Very high	8 Å²	8	14 Å²	14	4%	0.042	7%	0.071	C	C	.	.	H	α-helix	trans	-62	-38.2	176.2	-64.3	178	0	0	0	112.2	C162 F163 I166 F391 M392 S397 L398 Y399	C162-L395 HydrophobicContact CB-CD1 3.88Å; C162-L395 HydrophobicContact CB-CD2 4.13Å; F163-L395 HydrophobicContact CB-CB 4.1Å; F163-L395 HydrophobicContact CD2-CB 4.13Å; I166-L395 HydrophobicContact CD1-CD1 3.57Å; F391-L395 HydrophobicContact CD1-CD1 4.08Å; F391-L395 HydrophobicContact CD1-CG 4.45Å; F391-L395 HydrophobicContact CE1-CD1 3.68Å; F391-L395 HydrophobicContact CE1-CD2 4.49Å; F391-L395 HydrophobicContact CE1-CG 4.13Å; F391-L395 HydrophobicContact CZ-CD1 4.28Å; F391-L395 HydrophobicContact CZ-CD2 4.28Å; F391-L395 HydrophobicContact CZ-CG 4.33Å; F391-L395 WeakPolarHBondContact O-CG 3.38Å; F391-L395 PolarHBondContact O-N 2.91Å; M392-L395 PolarHBondContact O-N 3.43Å; L395-S397 VanDerWaalsContact C-N 3.32Å; L395-S397 PolarHBondContact O-N 3.39Å; L395-L398 PolarHBondContact O-N 3.07Å; L395-Y399 PolarHBondContact O-N 3.49Å
396	A	95.4	Very high	92.1	Very high	0 Å²	0	12.2 Å²	12.2	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-58.2	-42.9	175.7	0	0	0	0	0	111.7	L46 F163 F324 M392 L393 F394 L398 Y399 I400	L46-A396 HydrophobicContact CD2-CB 3.77Å; F163-A396 VanDerWaalsContact CD2-CA 3.47Å; F163-A396 HydrophobicContact CD2-CB 3.85Å; F163-A396 HydrophobicContact CE2-CB 3.38Å; F163-A396 HydrophobicContact CZ-CB 3.92Å; F324-A396 HydrophobicContact CE2-CB 3.69Å; F324-A396 HydrophobicContact CZ-CB 4.18Å; M392-A396 VanDerWaalsContact O-CB 3.29Å; M392-A396 WeakPolarHBondContact O-CB 3.44Å; M392-A396 PolarHBondContact O-N 3.11Å; L393-A396 WeakPolarHBondContact O-CB 3.42Å; L393-A396 PolarHBondContact O-N 3.36Å; F394-A396 VanDerWaalsContact C-N 3.3Å; F394-A396 PolarHBondContact O-N 3.3Å; A396-L398 PolarHBondContact O-N 3.37Å; A396-Y399 PolarHBondContact O-N 3.22Å; A396-I400 PolarHBondContact O-N 2.81Å
397	S	96.3	Very high	91.9	Very high	2 Å²	2	12.5 Å²	12.5	1%	0.014	6%	0.06	C	C	.	.	H	α-helix	trans	-65.6	-36.3	177.2	73.3	0	0	0	0	113	A98 L393 F394 L395 M401	A98-S397 WeakPolarHBondContact CA-OG 3.08Å; A98-S397 WeakPolarHBondContact CB-OG 3.43Å; L393-S397 PolarHBondContact O-N 3.46Å; F394-S397 PolarHBondContact O-N 2.89Å; F394-S397 PolarHBondContact O-OG 3.49Å; L395-S397 VanDerWaalsContact C-N 3.32Å; L395-S397 PolarHBondContact O-N 3.39Å; S397-M401 PolarHBondContact O-N 3.4Å; S397-M401 VanDerWaalsContact O-N 3.12Å
398	L	96.3	Very high	91.3	Very high	2 Å²	2	13.3 Å²	13.3	1%	0.01	6%	0.06	C	C	.	.	H	α-helix	trans	-68.9	-41.4	173.9	-64.8	179.9	0	0	0	111.6	A98 W152 V155 F394 L395 A396 M401 M402	A98-L398 HydrophobicContact CB-CD2 4.14Å; W152-L398 HydrophobicContact CH2-CD2 3.94Å; W152-L398 HydrophobicContact CZ2-CD2 3.37Å; V155-L398 HydrophobicContact CG1-CD1 4.26Å; F394-L398 HydrophobicContact CE1-CD1 3.96Å; F394-L398 HydrophobicContact CE2-CD1 3.98Å; F394-L398 HydrophobicContact CE2-CG 4.36Å; F394-L398 HydrophobicContact CZ-CD1 3.61Å; F394-L398 HydrophobicContact CZ-CG 4.46Å; F394-L398 PolarHBondContact O-N 3.42Å; L395-L398 PolarHBondContact O-N 3.07Å; A396-L398 PolarHBondContact O-N 3.37Å; L398-M401 HydrophobicContact CD2-CE 4.47Å; L398-M401 WeakPolarHBondContact O-CB 3.36Å; L398-M401 PolarHBondContact O-N 3.07Å; L398-M402 WeakPolarHBondContact O-CG 3.37Å; L398-M402 PolarHBondContact O-N 3.44Å; L398-M402 VanDerWaalsContact O-N 3.13Å
399	Y	94.9	Very high	90.5	Very high	9 Å²	9	13.2 Å²	13.2	4%	0.035	6%	0.058	C	C	.	.	H	α-helix	trans	-59.9	-46.2	175.2	173.6	-93.4	0	0	0	112.4	A160 F163 I164 F324 L395 A396 M401 M402 T403	A160-Y399 HydrophobicContact CB-CD2 4.16Å; F163-Y399 HydrophobicContact CB-CG 4.4Å; F163-Y399 AromaticContact CD1-CD1 3.83Å; F163-Y399 HydrophobicContact CD1-CD1 3.83Å; F163-Y399 AromaticContact CD1-CD2 3.82Å; F163-Y399 HydrophobicContact CD1-CD2 3.82Å; F163-Y399 HydrophobicContact CD1-CE2 4.48Å; F163-Y399 AromaticContact CD1-CG 3.43Å; F163-Y399 HydrophobicContact CD1-CG 3.43Å; F163-Y399 VanDerWaalsContact CD1-CG 3.43Å; F163-Y399 AromaticContact CE1-CD1 3.96Å; F163-Y399 HydrophobicContact CE1-CD1 3.96Å; F163-Y399 HydrophobicContact CE1-CE1 4.48Å; F163-Y399 HydrophobicContact CE1-CG 4.06Å; F163-Y399 HydrophobicContact CG-CG 4.19Å; I164-Y399 HydrophobicContact CD1-CD2 4.37Å; I164-Y399 HydrophobicContact CD1-CE2 4.05Å; I164-Y399 HydrophobicContact CG1-CD2 3.88Å; I164-Y399 HydrophobicContact CG1-CE2 3.59Å; F324-Y399 HydrophobicContact CB-CD1 4.44Å; F324-Y399 HydrophobicContact CB-CE1 3.95Å; F324-Y399 AromaticContact CD2-CD1 3.65Å; F324-Y399 HydrophobicContact CD2-CD1 3.65Å; F324-Y399 HydrophobicContact CD2-CE1 4.03Å; F324-Y399 HydrophobicContact CE2-CD1 4.32Å; F324-Y399 HydrophobicContact CG-CD1 4.4Å; F324-Y399 HydrophobicContact CG-CE1 4.39Å; L395-Y399 PolarHBondContact O-N 3.49Å; A396-Y399 PolarHBondContact O-N 3.22Å; Y399-M401 VanDerWaalsContact C-N 3.33Å; Y399-M401 PolarHBondContact O-N 2.99Å; Y399-M402 PolarHBondContact O-N 3.25Å; Y399-T403 WeakPolarHBondContact CE1-OG1 3.34Å; Y399-T403 WeakPolarHBondContact O-CB 3.1Å; Y399-T403 PolarHBondContact O-N 3.21Å; Y399-T403 PolarHBondContact O-OG1 3.42Å
400	I	93.6	Very high	89.4	Confident	3 Å²	3	15.8 Å²	15.8	2%	0.015	7%	0.068	C	C	.	.	H	α-helix	trans	-63.2	-41.9	178.2	-76.1	-56.8	0	0	0	111.4	V50 L321 F324 A396 M402 T403 L404	V50-I400 HydrophobicContact CB-CG2 4.43Å; V50-I400 HydrophobicContact CG1-CD1 4.45Å; V50-I400 HydrophobicContact CG1-CG2 3.97Å; V50-I400 HydrophobicContact CG2-CB 4.47Å; V50-I400 HydrophobicContact CG2-CG1 4.02Å; V50-I400 HydrophobicContact CG2-CG2 3.91Å; L321-I400 HydrophobicContact CD1-CD1 3.91Å; F324-I400 HydrophobicContact CB-CD1 4.1Å; F324-I400 HydrophobicContact CD1-CD1 3.55Å; F324-I400 HydrophobicContact CD1-CG1 3.98Å; F324-I400 HydrophobicContact CD2-CD1 3.66Å; F324-I400 HydrophobicContact CD2-CG1 3.73Å; F324-I400 HydrophobicContact CE1-CD1 3.76Å; F324-I400 HydrophobicContact CE1-CG1 3.65Å; F324-I400 HydrophobicContact CE2-CD1 3.83Å; F324-I400 HydrophobicContact CE2-CG1 3.36Å; F324-I400 HydrophobicContact CG-CD1 3.49Å; F324-I400 VanDerWaalsContact CG-CD1 3.49Å; F324-I400 HydrophobicContact CG-CG1 4.01Å; F324-I400 HydrophobicContact CZ-CD1 3.89Å; F324-I400 HydrophobicContact CZ-CG1 3.31Å; A396-I400 PolarHBondContact O-N 2.81Å; I400-M402 VanDerWaalsContact C-N 3.34Å; I400-M402 PolarHBondContact O-N 3.41Å; I400-T403 PolarHBondContact O-N 2.52Å; I400-L404 HydrophobicContact CG2-CD1 3.57Å; I400-L404 HydrophobicContact CG2-CG 3.98Å; I400-L404 WeakPolarHBondContact O-CB 3.38Å; I400-L404 VanDerWaalsContact O-CG 3.32Å; I400-L404 WeakPolarHBondContact O-CG 3.38Å; I400-L404 PolarHBondContact O-N 3.27Å
401	M	93.2	Very high	87.9	Confident	0 Å²	0	18.3 Å²	18.3	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-53.5	-53.7	174.9	-175	-175.3	67.7	0	0	111.1	V90 Y91 C94 W152 S397 L398 Y399 T403 L404 T405	V90-M401 HydrophobicContact CG1-CG 4.48Å; Y91-M401 HydrophobicContact CD1-CE 4.47Å; Y91-M401 HydrophobicContact CD1-SD 3.81Å; Y91-M401 HydrophobicContact CD2-CG 4.45Å; Y91-M401 HydrophobicContact CE1-CE 4.09Å; Y91-M401 HydrophobicContact CE1-SD 3.97Å; Y91-M401 HydrophobicContact CG-CG 4.47Å; Y91-M401 HydrophobicContact CG-SD 4.07Å; C94-M401 HydrophobicContact CB-CB 3.62Å; C94-M401 HydrophobicContact CB-CG 3.84Å; C94-M401 HydrophobicContact CB-SD 4.11Å; W152-M401 HydrophobicContact CG-CE 4.46Å; W152-M401 HydrophobicContact CG-SD 4.44Å; W152-M401 PolarHBondContact NE1-SD 3.22Å; S397-M401 PolarHBondContact O-N 3.4Å; S397-M401 VanDerWaalsContact O-N 3.12Å; L398-M401 HydrophobicContact CD2-CE 4.47Å; L398-M401 WeakPolarHBondContact O-CB 3.36Å; L398-M401 PolarHBondContact O-N 3.07Å; Y399-M401 VanDerWaalsContact C-N 3.33Å; Y399-M401 PolarHBondContact O-N 2.99Å; M401-T403 VanDerWaalsContact C-N 3.32Å; M401-T403 PolarHBondContact O-N 2.88Å; M401-L404 PolarHBondContact O-N 3.19Å; M401-T405 WeakPolarHBondContact O-CB 3.4Å; M401-T405 WeakPolarHBondContact O-CG2 3.49Å; M401-T405 PolarHBondContact O-N 3.09Å; M401-T405 PolarHBondContact O-OG1 2.77Å
402	M	91.5	Very high	86.2	Confident	0 Å²	0	20.1 Å²	20.1	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-64.5	-36.7	-178.4	-63	-54.4	-57.4	0	0	112.6	F153 G156 M157 A160 L398 Y399 I400 T405 N406 W407	F153-M402 HydrophobicContact CD2-CE 3.68Å; F153-M402 HydrophobicContact CD2-SD 4.38Å; F153-M402 HydrophobicContact CE2-CE 3.59Å; F153-M402 HydrophobicContact CZ-CE 4.44Å; G156-M402 VanDerWaalsContact C-CG 3.45Å; G156-M402 WeakPolarHBondContact O-CG 3.38Å; M157-M402 HydrophobicContact CG-CE 3.5Å; M157-M402 HydrophobicContact CG-SD 4.4Å; A160-M402 HydrophobicContact CB-CB 4.19Å; A160-M402 HydrophobicContact CB-CG 3.96Å; L398-M402 WeakPolarHBondContact O-CG 3.37Å; L398-M402 PolarHBondContact O-N 3.44Å; L398-M402 VanDerWaalsContact O-N 3.13Å; Y399-M402 PolarHBondContact O-N 3.25Å; I400-M402 VanDerWaalsContact C-N 3.34Å; I400-M402 PolarHBondContact O-N 3.41Å; M402-T405 PolarHBondContact O-OG1 3.41Å; M402-N406 PolarHBondContact O-N 3.35Å; M402-W407 HydrophobicContact CB-CD2 4.03Å; M402-W407 HydrophobicContact CB-CE3 4.39Å; M402-W407 HydrophobicContact CB-CG 4.48Å; M402-W407 HydrophobicContact CB-CH2 4.43Å; M402-W407 HydrophobicContact CB-CZ2 4.04Å; M402-W407 HydrophobicContact CE-CB 4.49Å; M402-W407 HydrophobicContact CE-CD2 4.19Å; M402-W407 HydrophobicContact CE-CE3 3.86Å; M402-W407 HydrophobicContact CE-CG 4.5Å; M402-W407 HydrophobicContact CE-CZ3 4.44Å; M402-W407 PolarHBondContact O-N 3.21Å
403	T	90.6	Very high	84.4	Confident	8 Å²	8	22.4 Å²	22.4	5%	0.049	12%	0.117	C	C	.	.	H	α-helix	trans	-70	-45.3	-179.7	-59.9	0	0	0	0	111.6	Y399 I400 M401 T405 N406	Y399-T403 WeakPolarHBondContact CE1-OG1 3.34Å; Y399-T403 WeakPolarHBondContact O-CB 3.1Å; Y399-T403 PolarHBondContact O-N 3.21Å; Y399-T403 PolarHBondContact O-OG1 3.42Å; I400-T403 PolarHBondContact O-N 2.52Å; M401-T403 VanDerWaalsContact C-N 3.32Å; M401-T403 PolarHBondContact O-N 2.88Å; T403-T405 VanDerWaalsContact C-N 3.27Å; T403-T405 PolarHBondContact O-N 3.32Å; T403-N406 PolarHBondContact O-N 2.65Å
404	L	88.2	Confident	82.5	Confident	12 Å²	12	24.2 Å²	24.2	6%	0.063	12%	0.123	C	C	.	.	H	α-helix	trans	-68.8	-27.7	177.7	-69.1	-177.9	0	0	0	112.4	A53 L57 V90 I400 M401 N406	A53-L404 HydrophobicContact CB-CD1 3.46Å; A53-L404 VanDerWaalsContact CB-CD1 3.46Å; L57-L404 HydrophobicContact CD1-CB 3.9Å; L57-L404 HydrophobicContact CD1-CD2 4.49Å; V90-L404 HydrophobicContact CG1-CB 4.21Å; V90-L404 HydrophobicContact CG1-CD1 4.42Å; I400-L404 HydrophobicContact CG2-CD1 3.57Å; I400-L404 HydrophobicContact CG2-CG 3.98Å; I400-L404 WeakPolarHBondContact O-CB 3.38Å; I400-L404 VanDerWaalsContact O-CG 3.32Å; I400-L404 WeakPolarHBondContact O-CG 3.38Å; I400-L404 PolarHBondContact O-N 3.27Å; M401-L404 PolarHBondContact O-N 3.19Å; L404-N406 VanDerWaalsContact C-N 3.28Å
405	T	84.5	Confident	80.6	Confident	0 Å²	0	28 Å²	28	0%	0	14%	0.141	C	C	.	.	T	Hydrogen-bonded Turn	trans	-92.6	13.6	176.6	65.7	0	0	0	0	112.8	Y87 V90 Y91 M401 M402 T403 W407 Y408	Y87-T405 HydrophobicContact CD1-CG2 3.95Å; Y87-T405 WeakPolarHBondContact CE1-O 3.34Å; V90-T405 HydrophobicContact CB-CG2 4.29Å; V90-T405 HydrophobicContact CG1-CG2 3.93Å; Y91-T405 HydrophobicContact CD2-CG2 3.78Å; Y91-T405 HydrophobicContact CE2-CG2 3.42Å; Y91-T405 VanDerWaalsContact CE2-CG2 3.42Å; M401-T405 WeakPolarHBondContact O-CB 3.4Å; M401-T405 WeakPolarHBondContact O-CG2 3.49Å; M401-T405 PolarHBondContact O-N 3.09Å; M401-T405 PolarHBondContact O-OG1 2.77Å; M402-T405 PolarHBondContact O-OG1 3.41Å; T403-T405 VanDerWaalsContact C-N 3.27Å; T403-T405 PolarHBondContact O-N 3.32Å; T405-W407 PolarHBondContact O-N 3.33Å; T405-Y408 PolarHBondContact O-N 3.12Å; T405-Y408 VanDerWaalsContact O-N 3.1Å
406	N	80.8	Confident	78.9	Confident	5 Å²	5	30 Å²	30	3%	0.027	15%	0.151	C	C	.	.	T	Hydrogen-bonded Turn	trans	52.9	23.6	177.9	-66.2	-65	0	0	0	114.5	Y87 H314 M402 T403 L404 Y408	Y87-N406 PolarHBondContact OH-ND2 3.05Å; H314-N406 PolarHBondContact CD2-OD1 2.72Å; H314-N406 VanDerWaalsContact CD2-OD1 3.3Å; M402-N406 PolarHBondContact O-N 3.35Å; T403-N406 PolarHBondContact O-N 2.65Å; L404-N406 VanDerWaalsContact C-N 3.28Å; N406-Y408 HydrophobicContact CB-CD2 3.69Å; N406-Y408 HydrophobicContact CB-CE2 3.52Å; N406-Y408 HydrophobicContact CB-CG 4.45Å; N406-Y408 PolarHBondContact O-N 3.04Å
407	W	85.2	Confident	77.4	Confident	7 Å²	7	34.3 Å²	34.3	3%	0.027	17%	0.17	C	C	.	.	T	Hydrogen-bonded Turn	trans	58.2	21.3	-176.1	-59.7	67.7	0	0	0	114.8	M157 A160 I164 M402 T405 A422 V425	M157-W407 HydrophobicContact CB-CZ3 4.41Å; M157-W407 HydrophobicContact CG-CE3 4.19Å; M157-W407 HydrophobicContact CG-CZ3 4.08Å; A160-W407 HydrophobicContact CB-CH2 3.39Å; A160-W407 HydrophobicContact CB-CZ2 3.78Å; A160-W407 HydrophobicContact CB-CZ3 4.26Å; I164-W407 HydrophobicContact CD1-CH2 4.28Å; I164-W407 HydrophobicContact CD1-CZ2 4.2Å; M402-W407 HydrophobicContact CB-CD2 4.03Å; M402-W407 HydrophobicContact CB-CE3 4.39Å; M402-W407 HydrophobicContact CB-CG 4.48Å; M402-W407 HydrophobicContact CB-CH2 4.43Å; M402-W407 HydrophobicContact CB-CZ2 4.04Å; M402-W407 HydrophobicContact CE-CB 4.49Å; M402-W407 HydrophobicContact CE-CD2 4.19Å; M402-W407 HydrophobicContact CE-CE3 3.86Å; M402-W407 HydrophobicContact CE-CG 4.5Å; M402-W407 HydrophobicContact CE-CZ3 4.44Å; M402-W407 PolarHBondContact O-N 3.21Å; T405-W407 PolarHBondContact O-N 3.33Å; W407-A422 HydrophobicContact CB-CB 3.65Å; W407-A422 HydrophobicContact CD2-CB 4.13Å; W407-A422 HydrophobicContact CE3-CB 3.79Å; W407-A422 HydrophobicContact CG-CB 4.13Å; W407-V425 HydrophobicContact CH2-CG1 3.65Å; W407-V425 HydrophobicContact CZ3-CB 4.24Å; W407-V425 HydrophobicContact CZ3-CG1 3.74Å
408	Y	77.4	Confident	76.1	Confident	38 Å²	38	35 Å²	35	15%	0.149	18%	0.175	C	C	.	.			trans	-74.1	137.4	176.5	-67.8	-48.3	0	0	0	111.4	Y87 F153 T405 N406 M416	Y87-Y408 HydrophobicContact CE1-CD2 4.17Å; F153-Y408 WeakPolarHBondContact CE2-O 3.43Å; T405-Y408 PolarHBondContact O-N 3.12Å; T405-Y408 VanDerWaalsContact O-N 3.1Å; N406-Y408 HydrophobicContact CB-CD2 3.69Å; N406-Y408 HydrophobicContact CB-CE2 3.52Å; N406-Y408 HydrophobicContact CB-CG 4.45Å; N406-Y408 PolarHBondContact O-N 3.04Å; Y408-M416 HydrophobicContact CD1-CB 4.38Å; Y408-M416 HydrophobicContact CD2-CB 4.18Å; Y408-M416 HydrophobicContact CD2-CG 4.48Å; Y408-M416 HydrophobicContact CD2-SD 3.93Å; Y408-M416 HydrophobicContact CG-CB 4Å; Y408-M416 HydrophobicContact CG-CG 4.5Å; Y408-M416 HydrophobicContact CG-SD 4.49Å
409	R	74.4	Confident	75.1	Confident	55 Å²	55	36.6 Å²	36.6	21%	0.208	18%	0.182	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-85.6	133.4	169	-174.2	-179.8	-177.7	-155.4	14.6	109.2	F153 Y154 E411 K417 Q419	F153-R409 HydrophobicContact CD1-CG 4.21Å; F153-R409 HydrophobicContact CE1-CB 3.98Å; F153-R409 HydrophobicContact CE1-CG 4.03Å; F153-R409 HydrophobicContact CE2-CB 4.06Å; F153-R409 HydrophobicContact CZ-CB 3.75Å; F153-R409 HydrophobicContact CZ-CG 4.3Å; Y154-R409 PolarHBondContact OH-NH2 3.35Å; Y154-R409 VanDerWaalsContact OH-NH2 3.15Å; R409-E411 IonicContact CZ-OE1 3.91Å; R409-E411 IonicContact NH1-OE1 3.5Å; R409-E411 PolarHBondContact NH1-OE1 2.93Å; R409-E411 PolarHBondContact O-N 3.47Å; R409-K417 PolarHBondContact N-O 3.38Å; R409-Q419 HydrophobicContact CB-CG 4.11Å
410	Y	67.1	Low	74.7	Confident	57 Å²	57	40.4 Å²	40.4	22%	0.224	20%	0.197	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-78.3	115.8	165.7	-177.4	-117.8	0	0	0	109.5	L84	L84-Y410 HydrophobicContact CD1-CD2 4.47Å; L84-Y410 HydrophobicContact CD2-CD2 3.45Å; L84-Y410 VanDerWaalsContact CD2-CD2 3.45Å; L84-Y410 HydrophobicContact CD2-CE2 3.1Å; L84-Y410 HydrophobicContact CG-CE2 4.5Å
411	E	63.9	Low	74.3	Confident	53 Å²	53	43.3 Å²	43.3	25%	0.248	21%	0.214	C	C	.	.			trans	-106.6	148.5	174.3	-151.2	140.5	-116.5	0	0	109.6	R409 S413 R414	R409-E411 IonicContact CZ-OE1 3.91Å; R409-E411 IonicContact NH1-OE1 3.5Å; R409-E411 PolarHBondContact NH1-OE1 2.93Å; R409-E411 PolarHBondContact O-N 3.47Å; E411-S413 PolarHBondContact O-N 3.43Å; E411-R414 WeakPolarHBondContact O-CA 3.43Å; E411-R414 PolarHBondContact O-N 3.09Å
412	P	56.4	Low	74	Confident	117 Å²	117	43.3 Å²	43.3	76%	0.76	21%	0.214	S	C	*	.	T	Hydrogen-bonded Turn	trans	-57.5	-21.5	179.4	-25.9	35.2	0	0	0	114	R414	P412-R414 PolarHBondContact O-N 3.46Å
413	S	55	Low	73.9	Confident	65 Å²	65	43.3 Å²	43.3	46%	0.455	21%	0.214	S	C	.	.	T	Hydrogen-bonded Turn	trans	-70	-1	171.4	55.3	0	0	0	0	114.1	E411 E415	E411-S413 PolarHBondContact O-N 3.43Å; S413-E415 PolarHBondContact O-N 3.3Å; S413-E415 VanDerWaalsContact O-N 3.16Å
414	R	55.8	Low	74	Confident	46 Å²	46	48.5 Å²	48.5	17%	0.174	23%	0.233	C	C	.	.			trans	61.1	16.4	178.4	-54.8	-175	177	-174	-1.9	115.1	E75 V79 E411 P412	E75-R414 VanDerWaalsContact CB-NH2 3.28Å; E75-R414 VanDerWaalsContact CD-NH2 3.26Å; E75-R414 PolarHBondContact O-NH1 3.14Å; E75-R414 IonicContact OE1-CZ 3.64Å; E75-R414 IonicContact OE1-NE 2.74Å; E75-R414 IonicContact OE1-NH2 3.3Å; E75-R414 PolarHBondContact OE1-NH2 3.35Å; E75-R414 IonicContact OE2-NH2 3.02Å; V79-R414 HydrophobicContact CB-CB 4.19Å; V79-R414 HydrophobicContact CG2-CB 4.15Å; E411-R414 WeakPolarHBondContact O-CA 3.43Å; E411-R414 PolarHBondContact O-N 3.09Å; P412-R414 PolarHBondContact O-N 3.46Å
415	E	56.6	Low	74.2	Confident	101 Å²	101	48.8 Å²	48.8	47%	0.472	24%	0.236	S	C	.	.			trans	-92.1	126.6	172.2	-67.9	178.5	164.4	0	0	109.2	S413 K417	S413-E415 PolarHBondContact O-N 3.3Å; S413-E415 VanDerWaalsContact O-N 3.16Å; E415-K417 HydrophobicContact CB-CG 4.24Å; E415-K417 PolarHBondContact O-N 3.49Å; E415-K417 VanDerWaalsContact O-N 3.17Å; E415-K417 WeakPolarHBondContact OE2-CE 3.44Å; E415-K417 IonicContact OE2-NZ 3.38Å; E415-K417 PolarHBondContact OE2-NZ 3.25Å
416	M	60.9	Low	74.6	Confident	51 Å²	51	49 Å²	49	25%	0.251	24%	0.237	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-74.6	102.2	166.9	-74.4	-173.7	145.1	0	0	108.4	L84 Y87 V310 Y408	L84-M416 HydrophobicContact CD1-CE 3.21Å; L84-M416 HydrophobicContact CD1-SD 4.41Å; Y87-M416 HydrophobicContact CD1-CE 3.2Å; Y87-M416 HydrophobicContact CD2-CE 3.75Å; Y87-M416 HydrophobicContact CE1-CE 3.31Å; Y87-M416 HydrophobicContact CE1-SD 4.08Å; Y87-M416 HydrophobicContact CE2-CE 3.87Å; Y87-M416 HydrophobicContact CE2-SD 4.4Å; Y87-M416 HydrophobicContact CG-CE 3.42Å; Y87-M416 VanDerWaalsContact CG-CE 3.42Å; V310-M416 HydrophobicContact CG1-SD 4.2Å; V310-M416 HydrophobicContact CG2-SD 4.5Å; Y408-M416 HydrophobicContact CD1-CB 4.38Å; Y408-M416 HydrophobicContact CD2-CB 4.18Å; Y408-M416 HydrophobicContact CD2-CG 4.48Å; Y408-M416 HydrophobicContact CD2-SD 3.93Å; Y408-M416 HydrophobicContact CG-CB 4Å; Y408-M416 HydrophobicContact CG-CG 4.5Å; Y408-M416 HydrophobicContact CG-SD 4.49Å
417	K	63.6	Low	75.3	Confident	90 Å²	90	48.8 Å²	48.8	39%	0.391	24%	0.235	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-100	129.8	176.5	-68.7	-171.7	177.8	169.6	0	110.1	R409 E415	R409-K417 PolarHBondContact N-O 3.38Å; E415-K417 HydrophobicContact CB-CG 4.24Å; E415-K417 PolarHBondContact O-N 3.49Å; E415-K417 VanDerWaalsContact O-N 3.17Å; E415-K417 WeakPolarHBondContact OE2-CE 3.44Å; E415-K417 IonicContact OE2-NZ 3.38Å; E415-K417 PolarHBondContact OE2-NZ 3.25Å
418	S	67.9	Low	75.7	Confident	17 Å²	17	50.1 Å²	50.1	12%	0.119	25%	0.245	C	C	.	.			trans	-65.2	144	162.5	-150.9	0	0	0	0	109	N281 P283	N281-S418 WeakPolarHBondContact CA-OG 3.4Å; N281-S418 WeakPolarHBondContact O-CB 3.28Å; N281-S418 PolarHBondContact O-OG 3.21Å; P283-S418 WeakPolarHBondContact CB-O 3.42Å
419	Q	76.7	Confident	76.5	Confident	35 Å²	35	48.3 Å²	48.3	16%	0.164	24%	0.238	C	C	.	.			trans	-122.2	140.8	-178	-65.3	-157.7	-48.8	0	0	111.3	R409 T421 A422	R409-Q419 HydrophobicContact CB-CG 4.11Å; Q419-T421 PolarHBondContact O-N 3.37Å; Q419-A422 PolarHBondContact O-N 3.19Å
420	W	85.8	Confident	77.5	Confident	89 Å²	89	45.7 Å²	45.7	34%	0.337	23%	0.229	S	C	.	.	H	α-helix	trans	-51	-30.7	168.3	-77.3	109.2	0	0	0	112.6	E228 F232 E282 P283 A422 V423 W424	E228-W420 HydrophobicContact CB-CH2 3.84Å; E228-W420 HydrophobicContact CB-CZ3 4.13Å; E228-W420 HydrophobicContact CG-CH2 3.75Å; E228-W420 HydrophobicContact CG-CZ3 4.21Å; F232-W420 HydrophobicContact CE2-CZ3 4.23Å; F232-W420 HydrophobicContact CZ-CZ3 4.38Å; E282-W420 HydrophobicContact CG-CH2 3.72Å; E282-W420 HydrophobicContact CG-CZ2 3.97Å; E282-W420 HydrophobicContact CG-CZ3 4.25Å; E282-W420 VanDerWaalsContact OE1-CH2 3.29Å; E282-W420 WeakPolarHBondContact OE1-CH2 3.26Å; P283-W420 HydrophobicContact CG-CD2 4.19Å; P283-W420 HydrophobicContact CG-CG 4.09Å; P283-W420 HydrophobicContact CG-CZ2 4.29Å; W420-A422 VanDerWaalsContact C-N 3.32Å; W420-A422 PolarHBondContact O-N 3.36Å; W420-V423 HydrophobicContact CE3-CB 4.28Å; W420-V423 HydrophobicContact CE3-CG1 4.35Å; W420-V423 HydrophobicContact CE3-CG2 4.32Å; W420-V423 HydrophobicContact CZ3-CG1 4.39Å; W420-V423 WeakPolarHBondContact O-CB 3.44Å; W420-V423 PolarHBondContact O-N 3.25Å; W420-V423 VanDerWaalsContact O-N 3.15Å; W420-W424 PolarHBondContact O-N 2.98Å
421	T	85.6	Confident	78.8	Confident	63 Å²	63	47.1 Å²	47.1	39%	0.387	23%	0.234	S	C	.	.	H	α-helix	trans	-57.5	-42.9	176.5	-48.2	0	0	0	0	112.4	M157 Q419 V423 W424 V425	M157-T421 HydrophobicContact CE-CG2 4Å; M157-T421 HydrophobicContact SD-CG2 3.63Å; Q419-T421 PolarHBondContact O-N 3.37Å; T421-V423 VanDerWaalsContact C-N 3.34Å; T421-V423 PolarHBondContact O-N 2.8Å; T421-W424 PolarHBondContact O-N 3.5Å; T421-V425 WeakPolarHBondContact O-CB 3.32Å; T421-V425 VanDerWaalsContact O-CG2 3.26Å; T421-V425 WeakPolarHBondContact O-CG2 3.44Å; T421-V425 PolarHBondContact O-N 3.04Å
422	A	85.6	Confident	80.3	Confident	0 Å²	0	47.6 Å²	47.6	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-67.1	-37.3	177.6	0	0	0	0	0	111.8	N281 W407 Q419 W420 K426	N281-A422 HydrophobicContact CB-CB 4.29Å; W407-A422 HydrophobicContact CB-CB 3.65Å; W407-A422 HydrophobicContact CD2-CB 4.13Å; W407-A422 HydrophobicContact CE3-CB 3.79Å; W407-A422 HydrophobicContact CG-CB 4.13Å; Q419-A422 PolarHBondContact O-N 3.19Å; W420-A422 VanDerWaalsContact C-N 3.32Å; W420-A422 PolarHBondContact O-N 3.36Å; A422-K426 WeakPolarHBondContact O-CG 3.26Å; A422-K426 PolarHBondContact O-N 3.43Å
423	V	90.8	Very high	82	Confident	0 Å²	0	42.1 Å²	42.1	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-60.8	-52.8	174.6	-173.5	0	0	0	0	109.9	F232 A278 N281 W420 T421 V425 K426 I427	F232-V423 HydrophobicContact CD2-CG1 4.46Å; F232-V423 HydrophobicContact CE2-CG1 3.7Å; F232-V423 HydrophobicContact CZ-CG1 4.22Å; A278-V423 HydrophobicContact CB-CG1 4.03Å; A278-V423 WeakPolarHBondContact O-CG2 3.38Å; N281-V423 HydrophobicContact CB-CG2 4.24Å; N281-V423 VanDerWaalsContact O-CG2 3.23Å; N281-V423 WeakPolarHBondContact O-CG2 3.4Å; W420-V423 HydrophobicContact CE3-CB 4.28Å; W420-V423 HydrophobicContact CE3-CG1 4.35Å; W420-V423 HydrophobicContact CE3-CG2 4.32Å; W420-V423 HydrophobicContact CZ3-CG1 4.39Å; W420-V423 WeakPolarHBondContact O-CB 3.44Å; W420-V423 PolarHBondContact O-N 3.25Å; W420-V423 VanDerWaalsContact O-N 3.15Å; T421-V423 VanDerWaalsContact C-N 3.34Å; T421-V423 PolarHBondContact O-N 2.8Å; V423-V425 PolarHBondContact O-N 3.28Å; V423-K426 PolarHBondContact O-N 2.83Å; V423-K426 VanDerWaalsContact O-N 3.14Å; V423-I427 HydrophobicContact CG1-CG1 4.23Å; V423-I427 WeakPolarHBondContact O-CG1 3.36Å; V423-I427 PolarHBondContact O-N 3.23Å
424	W	92.8	Very high	83.9	Confident	117 Å²	117	39.3 Å²	39.3	44%	0.443	18%	0.182	S	C	.	.	H	α-helix	trans	-64.1	-37.3	-178.3	-79.4	111.6	0	0	0	113.1	F232 W420 T421 K426 S428 W431	F232-W424 HydrophobicContact CE1-CH2 4.08Å; F232-W424 HydrophobicContact CE1-CZ2 4.44Å; F232-W424 HydrophobicContact CE1-CZ3 4.33Å; F232-W424 HydrophobicContact CZ-CH2 4.45Å; F232-W424 HydrophobicContact CZ-CZ2 4.36Å; W420-W424 PolarHBondContact O-N 2.98Å; T421-W424 PolarHBondContact O-N 3.5Å; W424-K426 VanDerWaalsContact C-N 3.31Å; W424-K426 PolarHBondContact O-N 3.39Å; W424-S428 WeakPolarHBondContact O-CB 3.35Å; W424-S428 PolarHBondContact O-N 3.12Å; W424-S428 PolarHBondContact O-OG 3.32Å; W424-W431 HydrophobicContact CZ3-CH2 4.03Å; W424-W431 HydrophobicContact CZ3-CZ3 4.31Å
425	V	91.9	Very high	85.7	Confident	19 Å²	19	41.7 Å²	41.7	12%	0.115	20%	0.201	C	C	.	.	H	α-helix	trans	-57.7	-45.7	173.3	163.2	0	0	0	0	110.7	F161 I164 W407 T421 V423 S428 S429	F161-V425 HydrophobicContact CB-CG1 3.87Å; F161-V425 HydrophobicContact CD2-CG1 4.01Å; F161-V425 HydrophobicContact CG-CG1 4.42Å; I164-V425 HydrophobicContact CD1-CG1 4.44Å; W407-V425 HydrophobicContact CH2-CG1 3.65Å; W407-V425 HydrophobicContact CZ3-CB 4.24Å; W407-V425 HydrophobicContact CZ3-CG1 3.74Å; T421-V425 WeakPolarHBondContact O-CB 3.32Å; T421-V425 VanDerWaalsContact O-CG2 3.26Å; T421-V425 WeakPolarHBondContact O-CG2 3.44Å; T421-V425 PolarHBondContact O-N 3.04Å; V423-V425 PolarHBondContact O-N 3.28Å; V425-S428 PolarHBondContact O-OG 3.34Å; V425-S429 VanDerWaalsContact O-CB 3.29Å; V425-S429 WeakPolarHBondContact O-CB 3.5Å; V425-S429 PolarHBondContact O-N 3Å; V425-S429 VanDerWaalsContact O-N 3.13Å; V425-S429 PolarHBondContact O-OG 3.2Å
426	K	92.8	Very high	87.4	Confident	5 Å²	5	39.8 Å²	39.8	2%	0.022	19%	0.194	C	C	.	.	H	α-helix	trans	-73.2	-43.6	-179.2	-67.5	175.7	-178.3	-175.6	0	112.7	S277 A278 N281 A422 V423 W424 S429 S430	S277-K426 WeakPolarHBondContact O-CD 3.37Å; S277-K426 PolarHBondContact O-NZ 3.12Å; S277-K426 WeakPolarHBondContact OG-CE 3.39Å; S277-K426 PolarHBondContact OG-NZ 3.15Å; A278-K426 HydrophobicContact CB-CB 3.78Å; A278-K426 HydrophobicContact CB-CD 4.33Å; N281-K426 PolarHBondContact ND2-NZ 2.91Å; A422-K426 WeakPolarHBondContact O-CG 3.26Å; A422-K426 PolarHBondContact O-N 3.43Å; V423-K426 PolarHBondContact O-N 2.83Å; V423-K426 VanDerWaalsContact O-N 3.14Å; W424-K426 VanDerWaalsContact C-N 3.31Å; W424-K426 PolarHBondContact O-N 3.39Å; K426-S429 PolarHBondContact O-N 2.95Å; K426-S430 PolarHBondContact O-N 3.35Å
427	I	94.9	Very high	88.9	Confident	0 Å²	0	37.4 Å²	37.4	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-66.1	-47.8	178.7	-67	-58.5	0	0	0	111.4	F232 A278 V423 S429 S430 W431	F232-I427 HydrophobicContact CB-CD1 3.99Å; F232-I427 HydrophobicContact CD1-CD1 4.31Å; F232-I427 HydrophobicContact CD1-CG1 4.12Å; F232-I427 HydrophobicContact CD1-CG2 3.96Å; F232-I427 HydrophobicContact CD2-CD1 4.22Å; F232-I427 HydrophobicContact CD2-CG1 4.17Å; F232-I427 HydrophobicContact CE1-CG1 4.3Å; F232-I427 HydrophobicContact CE1-CG2 4.15Å; F232-I427 HydrophobicContact CE2-CG1 4.34Å; F232-I427 HydrophobicContact CG-CD1 3.93Å; F232-I427 HydrophobicContact CG-CG1 4.07Å; F232-I427 HydrophobicContact CZ-CG1 4.41Å; A278-I427 HydrophobicContact CB-CD1 3.58Å; A278-I427 HydrophobicContact CB-CG1 3.67Å; V423-I427 HydrophobicContact CG1-CG1 4.23Å; V423-I427 WeakPolarHBondContact O-CG1 3.36Å; V423-I427 PolarHBondContact O-N 3.23Å; I427-S429 VanDerWaalsContact C-N 3.31Å; I427-S429 PolarHBondContact O-N 3.11Å; I427-S430 WeakPolarHBondContact O-CB 3.28Å; I427-S430 PolarHBondContact O-N 3.36Å; I427-S430 PolarHBondContact O-OG 3.25Å; I427-W431 HydrophobicContact CG2-CD2 4.16Å; I427-W431 HydrophobicContact CG2-CH2 4.01Å; I427-W431 HydrophobicContact CG2-CZ2 3.46Å; I427-W431 VanDerWaalsContact CG2-CZ2 3.46Å; I427-W431 PolarHBondContact O-N 3.09Å; I427-W431 VanDerWaalsContact O-N 3.08Å
428	S	94.5	Very high	90.2	Very high	34 Å²	34	34.5 Å²	34.5	24%	0.238	17%	0.172	C	C	.	.	H	α-helix	trans	-61.6	-40.4	176.7	60.6	0	0	0	0	111.8	W424 V425 S430 W431 I432	W424-S428 WeakPolarHBondContact O-CB 3.35Å; W424-S428 PolarHBondContact O-N 3.12Å; W424-S428 PolarHBondContact O-OG 3.32Å; V425-S428 PolarHBondContact O-OG 3.34Å; S428-S430 VanDerWaalsContact C-N 3.29Å; S428-S430 PolarHBondContact O-N 2.83Å; S428-W431 PolarHBondContact O-N 2.84Å; S428-I432 VanDerWaalsContact O-CG1 3.28Å; S428-I432 WeakPolarHBondContact O-CG1 3.28Å; S428-I432 PolarHBondContact O-N 2.96Å
429	S	93.5	Very high	91.3	Very high	0 Å²	0	40.3 Å²	40.3	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-59.1	-40.3	172.4	-60.1	0	0	0	0	111.9	F161 L168 V425 K426 I427 W431 I432 G433	F161-S429 VanDerWaalsContact CD2-OG 3.25Å; F161-S429 WeakPolarHBondContact CD2-OG 3.07Å; F161-S429 WeakPolarHBondContact CE2-OG 3.46Å; L168-S429 WeakPolarHBondContact CD1-O 3.4Å; V425-S429 VanDerWaalsContact O-CB 3.29Å; V425-S429 WeakPolarHBondContact O-CB 3.5Å; V425-S429 PolarHBondContact O-N 3Å; V425-S429 VanDerWaalsContact O-N 3.13Å; V425-S429 PolarHBondContact O-OG 3.2Å; K426-S429 PolarHBondContact O-N 2.95Å; I427-S429 VanDerWaalsContact C-N 3.31Å; I427-S429 PolarHBondContact O-N 3.11Å; S429-W431 PolarHBondContact O-N 3.44Å; S429-I432 PolarHBondContact O-N 3.13Å; S429-G433 PolarHBondContact O-N 3.16Å
430	S	94.7	Very high	91.8	Very high	1 Å²	1	40.7 Å²	40.7	1%	0.007	20%	0.196	C	C	.	.	H	α-helix	trans	-62.1	-42.8	177.2	79.4	0	0	0	0	112.2	N236 K426 I427 S428 G433 I434	N236-S430 PolarHBondContact ND2-OG 2.63Å; K426-S430 PolarHBondContact O-N 3.35Å; I427-S430 WeakPolarHBondContact O-CB 3.28Å; I427-S430 PolarHBondContact O-N 3.36Å; I427-S430 PolarHBondContact O-OG 3.25Å; S428-S430 VanDerWaalsContact C-N 3.29Å; S428-S430 PolarHBondContact O-N 2.83Å; S430-G433 PolarHBondContact O-N 3.06Å; S430-I434 WeakPolarHBondContact O-CG1 3.46Å; S430-I434 PolarHBondContact O-N 3.22Å
431	W	95.9	Very high	91.8	Very high	86 Å²	86	36.4 Å²	36.4	33%	0.326	18%	0.18	S	C	.	.	H	α-helix	trans	-66.9	-45	177.5	-61.4	-14.6	0	0	0	112	V235 N236 L239 W424 I427 S428 S429 G433 I434 V435	V235-W431 HydrophobicContact CG1-CZ2 4.23Å; N236-W431 PolarHBondContact OD1-NE1 3.37Å; L239-W431 HydrophobicContact CD1-CG 4.34Å; W424-W431 HydrophobicContact CZ3-CH2 4.03Å; W424-W431 HydrophobicContact CZ3-CZ3 4.31Å; I427-W431 HydrophobicContact CG2-CD2 4.16Å; I427-W431 HydrophobicContact CG2-CH2 4.01Å; I427-W431 HydrophobicContact CG2-CZ2 3.46Å; I427-W431 VanDerWaalsContact CG2-CZ2 3.46Å; I427-W431 PolarHBondContact O-N 3.09Å; I427-W431 VanDerWaalsContact O-N 3.08Å; S428-W431 PolarHBondContact O-N 2.84Å; S429-W431 PolarHBondContact O-N 3.44Å; W431-G433 VanDerWaalsContact C-N 3.28Å; W431-G433 PolarHBondContact O-N 3.23Å; W431-I434 PolarHBondContact O-N 3.15Å; W431-V435 WeakPolarHBondContact O-CG2 3.47Å; W431-V435 PolarHBondContact O-N 3.39Å
432	I	94.7	Very high	91.9	Very high	64 Å²	64	35.2 Å²	35.2	33%	0.328	17%	0.172	S	C	.	.	H	α-helix	trans	-60.3	-42.4	175.6	-65.7	165.5	0	0	0	110	F161 L165 S428 S429 I434 V435 L436	F161-I432 HydrophobicContact CE2-CD1 4.25Å; F161-I432 HydrophobicContact CZ-CD1 3.83Å; L165-I432 HydrophobicContact CD2-CB 3.99Å; L165-I432 HydrophobicContact CD2-CD1 4.18Å; L165-I432 HydrophobicContact CD2-CG2 3.64Å; S428-I432 VanDerWaalsContact O-CG1 3.28Å; S428-I432 WeakPolarHBondContact O-CG1 3.28Å; S428-I432 PolarHBondContact O-N 2.96Å; S429-I432 PolarHBondContact O-N 3.13Å; I432-I434 PolarHBondContact O-N 3.37Å; I432-V435 PolarHBondContact O-N 3.18Å; I432-L436 HydrophobicContact CG2-CD1 3.89Å; I432-L436 HydrophobicContact CG2-CG 4.15Å; I432-L436 WeakPolarHBondContact O-CB 3.28Å; I432-L436 VanDerWaalsContact O-CG 3.28Å; I432-L436 WeakPolarHBondContact O-CG 3.48Å; I432-L436 PolarHBondContact O-N 3.42Å
433	G	92.3	Very high	91.9	Very high	1 Å²	1	35.4 Å²	35.4	1%	0.01	17%	0.174	C	C	.	.	H	α-helix	trans	-58.5	-45.5	176.8	0	0	0	0	0	113.3	S429 S430 W431 L436 Y437	S429-G433 PolarHBondContact O-N 3.16Å; S430-G433 PolarHBondContact O-N 3.06Å; W431-G433 VanDerWaalsContact C-N 3.28Å; W431-G433 PolarHBondContact O-N 3.23Å; G433-L436 PolarHBondContact O-N 2.97Å; G433-Y437 PolarHBondContact O-N 2.83Å
434	I	94.3	Very high	91.5	Very high	6 Å²	6	36.3 Å²	36.3	3%	0.031	18%	0.18	C	C	.	.	H	α-helix	trans	-65.3	-44.1	175.7	-62.4	168.1	0	0	0	110.6	L239 A243 T271 S430 W431 I432 L436 Y437 V438	L239-I434 HydrophobicContact CB-CD1 3.58Å; L239-I434 HydrophobicContact CB-CG2 4.23Å; L239-I434 HydrophobicContact CD1-CD1 4.06Å; L239-I434 HydrophobicContact CG-CD1 4.48Å; A243-I434 HydrophobicContact CB-CG2 4.23Å; T271-I434 HydrophobicContact CG2-CD1 3.81Å; T271-I434 HydrophobicContact CG2-CG1 4.48Å; S430-I434 WeakPolarHBondContact O-CG1 3.46Å; S430-I434 PolarHBondContact O-N 3.22Å; W431-I434 PolarHBondContact O-N 3.15Å; I432-I434 PolarHBondContact O-N 3.37Å; I434-L436 VanDerWaalsContact C-N 3.32Å; I434-L436 PolarHBondContact O-N 3.31Å; I434-Y437 PolarHBondContact O-N 2.79Å; I434-V438 HydrophobicContact CG2-CG2 4.14Å; I434-V438 WeakPolarHBondContact O-CB 3.39Å; I434-V438 VanDerWaalsContact O-CG2 3.28Å; I434-V438 WeakPolarHBondContact O-CG2 3.47Å; I434-V438 PolarHBondContact O-N 3.33Å
435	V	94.2	Very high	90.9	Very high	97 Å²	97	34.1 Å²	34.1	59%	0.588	18%	0.176	S	C	*	.	H	α-helix	trans	-60.4	-43.1	177.5	169.8	0	0	0	0	111.2	W431 I432 V438 W439	W431-V435 WeakPolarHBondContact O-CG2 3.47Å; W431-V435 PolarHBondContact O-N 3.39Å; I432-V435 PolarHBondContact O-N 3.18Å; V435-V438 PolarHBondContact O-N 3.49Å; V435-W439 VanDerWaalsContact O-CB 3.26Å; V435-W439 WeakPolarHBondContact O-CB 3.46Å; V435-W439 PolarHBondContact O-N 2.82Å
436	L	92	Very high	90.5	Very high	60 Å²	60	37.4 Å²	37.4	31%	0.314	20%	0.197	S	C	.	.	H	α-helix	trans	-61.5	-44.8	175.8	-73.2	173.5	0	0	0	111.4	V169 I172 I432 G433 I434 W439 T440	V169-L436 HydrophobicContact CG2-CD1 4.1Å; I172-L436 HydrophobicContact CD1-CB 4.07Å; I432-L436 HydrophobicContact CG2-CD1 3.89Å; I432-L436 HydrophobicContact CG2-CG 4.15Å; I432-L436 WeakPolarHBondContact O-CB 3.28Å; I432-L436 VanDerWaalsContact O-CG 3.28Å; I432-L436 WeakPolarHBondContact O-CG 3.48Å; I432-L436 PolarHBondContact O-N 3.42Å; G433-L436 PolarHBondContact O-N 2.97Å; I434-L436 VanDerWaalsContact C-N 3.32Å; I434-L436 PolarHBondContact O-N 3.31Å; L436-W439 WeakPolarHBondContact O-CB 3.49Å; L436-W439 PolarHBondContact O-N 3.34Å; L436-T440 WeakPolarHBondContact O-CG2 3.4Å; L436-T440 PolarHBondContact O-N 3.28Å
437	Y	91.7	Very high	89.9	Confident	1 Å²	1	40.5 Å²	40.5	0%	0.004	21%	0.213	C	C	.	.	H	α-helix	trans	-62.9	-45.9	175.6	173	-107.1	0	0	0	112.4	I172 A243 S247 Q263 S264 I267 G433 I434 W439 T440 L441	I172-Y437 HydrophobicContact CG1-CD2 4.48Å; I172-Y437 HydrophobicContact CG2-CD2 4.33Å; A243-Y437 HydrophobicContact CB-CD1 4.12Å; A243-Y437 HydrophobicContact CB-CE1 4.15Å; S247-Y437 PolarHBondContact OG-OH 3.22Å; Q263-Y437 HydrophobicContact CB-CE2 3.82Å; S264-Y437 WeakPolarHBondContact CA-OH 3.32Å; S264-Y437 WeakPolarHBondContact CB-OH 3.26Å; S264-Y437 PolarHBondContact N-OH 3.16Å; S264-Y437 VanDerWaalsContact N-OH 3.15Å; I267-Y437 HydrophobicContact CB-CG 4.5Å; I267-Y437 HydrophobicContact CG1-CD1 4.47Å; I267-Y437 HydrophobicContact CG1-CD2 3.8Å; I267-Y437 HydrophobicContact CG1-CE2 4.21Å; I267-Y437 HydrophobicContact CG1-CG 3.94Å; I267-Y437 HydrophobicContact CG2-CD1 4.44Å; I267-Y437 HydrophobicContact CG2-CG 4.32Å; G433-Y437 PolarHBondContact O-N 2.83Å; I434-Y437 PolarHBondContact O-N 2.79Å; Y437-W439 PolarHBondContact O-N 3.08Å; Y437-T440 PolarHBondContact O-N 3.39Å; Y437-T440 VanDerWaalsContact O-N 3.12Å; Y437-T440 PolarHBondContact O-OG1 3.45Å; Y437-L441 HydrophobicContact CD1-CD1 4.39Å; Y437-L441 HydrophobicContact CE1-CD1 3.69Å; Y437-L441 HydrophobicContact CE1-CG 4.44Å; Y437-L441 HydrophobicContact CE2-CG 4.48Å; Y437-L441 PolarHBondContact O-N 3.29Å
438	V	91.8	Very high	88.5	Confident	30 Å²	30	45.8 Å²	45.8	18%	0.182	25%	0.245	C	C	.	.	H	α-helix	trans	-62.2	-37.6	176.6	171.5	0	0	0	0	110.6	A243 M246 I434 V435 T440 L441 V442	A243-V438 HydrophobicContact CB-CG2 4Å; M246-V438 HydrophobicContact CE-CB 4.05Å; M246-V438 HydrophobicContact CE-CG1 3.44Å; M246-V438 VanDerWaalsContact CE-CG1 3.44Å; M246-V438 HydrophobicContact CE-CG2 3.36Å; M246-V438 HydrophobicContact SD-CG1 3.75Å; I434-V438 HydrophobicContact CG2-CG2 4.14Å; I434-V438 WeakPolarHBondContact O-CB 3.39Å; I434-V438 VanDerWaalsContact O-CG2 3.28Å; I434-V438 WeakPolarHBondContact O-CG2 3.47Å; I434-V438 PolarHBondContact O-N 3.33Å; V435-V438 PolarHBondContact O-N 3.49Å; V438-T440 PolarHBondContact O-N 3Å; V438-L441 PolarHBondContact O-N 2.89Å; V438-V442 HydrophobicContact CG1-CG2 4.18Å; V438-V442 WeakPolarHBondContact O-CB 3.48Å; V438-V442 WeakPolarHBondContact O-CG2 3.09Å; V438-V442 PolarHBondContact O-N 2.96Å
439	W	90.6	Very high	86.9	Confident	138 Å²	138	52 Å²	52	52%	0.523	28%	0.276	S	S	.	.	H	α-helix	trans	-63.9	-37	174.9	-173.9	-102.5	0	0	0	112.4	V435 L436 Y437 L441 V442 A443	V435-W439 VanDerWaalsContact O-CB 3.26Å; V435-W439 WeakPolarHBondContact O-CB 3.46Å; V435-W439 PolarHBondContact O-N 2.82Å; L436-W439 WeakPolarHBondContact O-CB 3.49Å; L436-W439 PolarHBondContact O-N 3.34Å; Y437-W439 PolarHBondContact O-N 3.08Å; W439-L441 PolarHBondContact O-N 3.48Å; W439-V442 PolarHBondContact O-N 3.39Å; W439-A443 HydrophobicContact CD2-CB 4.44Å; W439-A443 HydrophobicContact CZ2-CB 4.45Å; W439-A443 WeakPolarHBondContact O-CB 3.28Å; W439-A443 PolarHBondContact O-N 2.85Å
440	T	86.9	Confident	85.2	Confident	43 Å²	43	58.2 Å²	58.2	26%	0.264	30%	0.299	S	S	.	.	H	α-helix	trans	-63.4	-31.8	175.2	65.4	0	0	0	0	112.5	I172 H176 L436 Y437 V438	I172-T440 HydrophobicContact CG2-CG2 4.1Å; H176-T440 PolarHBondContact NE2-OG1 3.11Å; L436-T440 WeakPolarHBondContact O-CG2 3.4Å; L436-T440 PolarHBondContact O-N 3.28Å; Y437-T440 PolarHBondContact O-N 3.39Å; Y437-T440 VanDerWaalsContact O-N 3.12Å; Y437-T440 PolarHBondContact O-OG1 3.45Å; V438-T440 PolarHBondContact O-N 3Å
441	L	86.3	Confident	83.3	Confident	0 Å²	0	65 Å²	65	0%	0	34%	0.336	C	S	.	.	H	α-helix	trans	-76.3	-37.9	175.6	-59.9	176.4	0	0	0	113.2	S247 I252 S259 Y437 V438 W439	S247-L441 WeakPolarHBondContact OG-CD1 3.47Å; I252-L441 HydrophobicContact CD1-CB 4.47Å; I252-L441 HydrophobicContact CG2-CB 4.13Å; I252-L441 HydrophobicContact CG2-CD2 4.43Å; S259-L441 WeakPolarHBondContact OG-CD2 3.33Å; Y437-L441 HydrophobicContact CD1-CD1 4.39Å; Y437-L441 HydrophobicContact CE1-CD1 3.69Å; Y437-L441 HydrophobicContact CE1-CG 4.44Å; Y437-L441 HydrophobicContact CE2-CG 4.48Å; Y437-L441 PolarHBondContact O-N 3.29Å; V438-L441 PolarHBondContact O-N 2.89Å; W439-L441 PolarHBondContact O-N 3.48Å
442	V	87.1	Confident	81.4	Confident	37 Å²	37	63.8 Å²	63.8	22%	0.224	33%	0.333	C	S	.	.	H	α-helix	trans	-92.4	-27.7	-171.5	175.3	0	0	0	0	112.7	I252 V438 W439 P444 L445 V446	I252-V442 HydrophobicContact CD1-CG2 4.41Å; V438-V442 HydrophobicContact CG1-CG2 4.18Å; V438-V442 WeakPolarHBondContact O-CB 3.48Å; V438-V442 WeakPolarHBondContact O-CG2 3.09Å; V438-V442 PolarHBondContact O-N 2.96Å; W439-V442 PolarHBondContact O-N 3.39Å; V442-P444 VanDerWaalsContact C-CD 3.46Å; V442-P444 VanDerWaalsContact C-N 3.34Å; V442-L445 WeakPolarHBondContact O-CB 3.45Å; V442-L445 PolarHBondContact O-N 3.27Å; V442-V446 HydrophobicContact CG1-CG2 3.7Å; V442-V446 PolarHBondContact O-N 2.77Å
443	A	86.7	Confident	78.8	Confident	5 Å²	5	70.4 Å²	70.4	4%	0.041	37%	0.369	C	S	.	.	H	α-helix	trans	-53.9	-41.2	-177.4	0	0	0	0	0	113.9	W439 L445 V446 L447 F452	W439-A443 HydrophobicContact CD2-CB 4.44Å; W439-A443 HydrophobicContact CZ2-CB 4.45Å; W439-A443 WeakPolarHBondContact O-CB 3.28Å; W439-A443 PolarHBondContact O-N 2.85Å; A443-L445 PolarHBondContact O-N 2.79Å; A443-V446 PolarHBondContact O-N 2.77Å; A443-L447 HydrophobicContact CB-CD1 4.48Å; A443-L447 WeakPolarHBondContact O-CB 3.31Å; A443-L447 PolarHBondContact O-N 3.36Å; A443-F452 HydrophobicContact CB-CE1 4.2Å; A443-F452 HydrophobicContact CB-CZ 4.22Å
444	P	81.2	Confident	78.1	Confident	18 Å²	18	73.9 Å²	73.9	12%	0.117	39%	0.387	C	S	.	.	H	α-helix	trans	-61.4	-28	175.4	-24.8	36.5	0	0	0	114.5	Q256 V442 F452	Q256-P444 HydrophobicContact CG-CB 4.36Å; Q256-P444 HydrophobicContact CG-CG 3.88Å; V442-P444 VanDerWaalsContact C-CD 3.46Å; V442-P444 VanDerWaalsContact C-N 3.34Å; P444-F452 HydrophobicContact CB-CD2 4.07Å; P444-F452 HydrophobicContact CB-CE2 4.31Å; P444-F452 HydrophobicContact CB-CG 4.3Å; P444-F452 HydrophobicContact CG-CD1 4.14Å; P444-F452 HydrophobicContact CG-CD2 4.36Å; P444-F452 HydrophobicContact CG-CE1 4.3Å; P444-F452 HydrophobicContact CG-CG 4.15Å
445	L	81.8	Confident	77.3	Confident	71 Å²	71	77.5 Å²	77.5	37%	0.372	41%	0.405	S	S	.	.	H	α-helix	trans	-79.6	-35	177.7	-65.9	173.5	0	0	0	112.8	K251 I252 S255 V442 A443	K251-L445 WeakPolarHBondContact O-CD2 3.34Å; I252-L445 HydrophobicContact CG1-CD1 3.59Å; S255-L445 WeakPolarHBondContact OG-CD2 3.34Å; V442-L445 WeakPolarHBondContact O-CB 3.45Å; V442-L445 PolarHBondContact O-N 3.27Å; A443-L445 PolarHBondContact O-N 2.79Å
446	V	82.9	Confident	76.3	Confident	89 Å²	89	76.4 Å²	76.4	54%	0.539	40%	0.395	S	S	.	.	H	α-helix	trans	-85.8	-38.4	-175.8	177.6	0	0	0	0	111.2	V442 A443 T448	V442-V446 HydrophobicContact CG1-CG2 3.7Å; V442-V446 PolarHBondContact O-N 2.77Å; A443-V446 PolarHBondContact O-N 2.77Å; V446-T448 PolarHBondContact O-N 2.77Å
447	L	79.8	Confident	75.4	Confident	70 Å²	70	77.4 Å²	77.4	37%	0.366	40%	0.4	S	S	.	.			trans	-98.6	67	-176.2	-60.3	175.6	0	0	0	110.3	A443 N449 R450 F452	A443-L447 HydrophobicContact CB-CD1 4.48Å; A443-L447 WeakPolarHBondContact O-CB 3.31Å; A443-L447 PolarHBondContact O-N 3.36Å; L447-N449 PolarHBondContact O-N 3.27Å; L447-R450 PolarHBondContact O-N 3.01Å; L447-F452 HydrophobicContact CB-CE2 3.98Å; L447-F452 HydrophobicContact CB-CZ 3.87Å; L447-F452 HydrophobicContact CD1-CZ 4.08Å; L447-F452 WeakPolarHBondContact O-CE2 2.99Å
448	T	65.7	Low	74.4	Confident	111 Å²	111	82.1 Å²	82.1	68%	0.681	43%	0.425	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.5	-10.6	-179	58.9	0	0	0	0	114.6	V446	V446-T448 PolarHBondContact O-N 2.77Å
449	N	60.6	Low	73.2	Confident	163 Å²	163	85.6 Å²	85.6	87%	0.872	44%	0.441	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.8	17.8	-178.2	-65.1	-21.2	0	0	0	113.3	L447	L447-N449 PolarHBondContact O-N 3.27Å
450	R	57.6	Low	72	Confident	132 Å²	132	81.9 Å²	81.9	50%	0.498	44%	0.435	S	S	.	.	S	Bend	trans	-129.8	128.7	178.2	-164.3	171.9	84.8	143	6.9	109.7	L447 F452	L447-R450 PolarHBondContact O-N 3.01Å; R450-F452 HydrophobicContact CB-CD2 4.5Å; R450-F452 HydrophobicContact CB-CE2 3.93Å; R450-F452 HydrophobicContact CB-CZ 4.31Å; R450-F452 WeakPolarHBondContact O-CD2 3.44Å; R450-F452 VanDerWaalsContact O-CE2 3.31Å; R450-F452 WeakPolarHBondContact O-CE2 3.35Å; R450-F452 PolarHBondContact O-N 3.38Å
451	D	54.8	Low	70.8	Confident	144 Å²	144	84.8 Å²	84.8	77%	0.77	45%	0.448	S	S	*	.			trans	-70.4	125.9	172.6	-57.6	-35.4	0	0	0	109.1
452	F	55.7	Low	69.6	Low	60 Å²	60	91.9 Å²	91.9	26%	0.263	49%	0.486	S	S	.	.			trans	-109.4	10.5	-179.1	-73.6	-87.9	0	0	0	113.2	A443 P444 L447 R450	A443-F452 HydrophobicContact CB-CE1 4.2Å; A443-F452 HydrophobicContact CB-CZ 4.22Å; P444-F452 HydrophobicContact CB-CD2 4.07Å; P444-F452 HydrophobicContact CB-CE2 4.31Å; P444-F452 HydrophobicContact CB-CG 4.3Å; P444-F452 HydrophobicContact CG-CD1 4.14Å; P444-F452 HydrophobicContact CG-CD2 4.36Å; P444-F452 HydrophobicContact CG-CE1 4.3Å; P444-F452 HydrophobicContact CG-CG 4.15Å; L447-F452 HydrophobicContact CB-CE2 3.98Å; L447-F452 HydrophobicContact CB-CZ 3.87Å; L447-F452 HydrophobicContact CD1-CZ 4.08Å; L447-F452 WeakPolarHBondContact O-CE2 2.99Å; R450-F452 HydrophobicContact CB-CD2 4.5Å; R450-F452 HydrophobicContact CB-CE2 3.93Å; R450-F452 HydrophobicContact CB-CZ 4.31Å; R450-F452 WeakPolarHBondContact O-CD2 3.44Å; R450-F452 VanDerWaalsContact O-CE2 3.31Å; R450-F452 WeakPolarHBondContact O-CE2 3.35Å; R450-F452 PolarHBondContact O-N 3.38Å
453	D	40.9	Very low	68	Low	203 Å²	203	96.9 Å²	96.9	100%	1.086	51%	0.51	S	S	*	.			trans	-72.1	0	179	-64.5	-26.6	0	0	0	113.1	Q340	Q340-D453 PolarHBondContact NE2-O 3.29Å

Retrieved 453 of 453 residues in 838.2 ms (Link to these results)

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