A0A096N5Q6_PAPAN Loading...

Uracil nucleotide/cysteinyl leukotriene receptor

Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.

AlphaFold DB (A0A2K5L9R6), UniProt , Accession A0A096N5Q6, Species PAPAN (Papio anubis, Olive baboon), Gene GPR17, Length 371 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	36.9	Very low	33	Very low	250 Å²	250	177.8 Å²	177.8	100%	1.232	89%	0.894	S	S	*	*				0	128.1	0	-66.7	163.1	93.4	0	0	107.8
2	S	34	Very low	33.1	Very low	120 Å²	120	178.8 Å²	178.8	84%	0.839	89%	0.893	S	S	*	*			cis	-159.2	140.7	-18	179	0	0	0	0	104.9
3	K	32.7	Very low	33.6	Very low	198 Å²	198	174.3 Å²	174.3	86%	0.861	89%	0.885	S	S	*	*			trans	-73.2	150.9	176.4	-69.3	172.3	174.3	178.4	0	111
4	R	35.9	Very low	34	Very low	240 Å²	240	170.9 Å²	170.9	91%	0.906	88%	0.88	S	S	*	*			trans	-139	101.5	154.5	-73	-170.3	-166.9	-151.1	3.1	107.2
5	S	32.9	Very low	33.7	Very low	107 Å²	107	175.9 Å²	175.9	75%	0.748	88%	0.883	S	S	*	*				80.9	102.6	74.8	70.9	0	0	0	0	113.1
6	W	29.6	Very low	33.6	Very low	245 Å²	245	176.1 Å²	176.1	93%	0.928	88%	0.88	S	S	*	*			trans	-72.6	156.7	161.7	-77.6	73.9	0	0	0	111.6
7	W	31.5	Very low	33.4	Very low	254 Å²	254	173.5 Å²	173.5	96%	0.962	88%	0.876	S	S	*	*			trans	153.3	146.6	154.7	-80.3	115.7	0	0	0	106.3
8	A	33.3	Very low	33.1	Very low	88 Å²	88	172.4 Å²	172.4	73%	0.727	87%	0.872	S	S	*	*			cis	-170.6	154.4	-7.9	0	0	0	0	0	104.2
9	G	29.7	Very low	32.9	Very low	80 Å²	80	174.6 Å²	174.6	83%	0.825	88%	0.875	S	S	*	*			trans	167.3	71	170.6	0	0	0	0	0	116.3
10	S	31.2	Very low	32.7	Very low	122 Å²	122	173.8 Å²	173.8	85%	0.853	87%	0.873	S	S	*	*			trans	-72.3	133.9	166.3	26.4	0	0	0	0	111.8
11	R	34.8	Very low	32.5	Very low	252 Å²	252	171.4 Å²	171.4	95%	0.951	87%	0.873	S	S	*	*			trans	-144.9	116.8	157.8	-71	-169.3	-160.7	-161.4	4.4	110.9
12	Q	35	Very low	32	Very low	190 Å²	190	162.7 Å²	162.7	89%	0.888	85%	0.847	S	S	*	*			trans	-81	159.4	157.4	-82.2	178.5	-33	0	0	110
13	P	38.6	Very low	31.6	Very low	120 Å²	120	162.6 Å²	162.6	78%	0.779	85%	0.846	S	S	*	*				-145.1	-170.2	119.6	43.2	-27	0	0	0	112.1
14	P	39.3	Very low	31.3	Very low	126 Å²	126	164.1 Å²	164.1	82%	0.818	85%	0.848	S	S	*	*				-116.1	174.2	-98.1	27.4	-5.3	0	0	0	115.1
15	R	30.6	Very low	31.3	Very low	246 Å²	246	158.6 Å²	158.6	93%	0.928	84%	0.844	S	S	*	*			trans	-82.5	136.6	170	-71.2	179	-177.2	-169.9	0.1	111.3
16	E	32.1	Very low	31	Very low	179 Å²	179	157 Å²	157	84%	0.836	84%	0.844	S	S	*	*			trans	-138.5	101.5	157.7	-76.9	-172.5	160.2	0	0	107.8
17	T	30.3	Very low	31	Very low	133 Å²	133	150.8 Å²	150.8	82%	0.816	84%	0.838	S	S	*	*				64.9	109.4	103.7	48	0	0	0	0	116.7
18	L	28	Very low	30.7	Very low	154 Å²	154	146.2 Å²	146.2	81%	0.806	83%	0.832	S	S	*	*			trans	-48.7	138.3	161.4	-85.9	80.4	0	0	0	112.3	L20	L18-L20 HydrophobicContact CD2-CD1 4.03Å
19	K	28.8	Very low	30.4	Very low	213 Å²	213	146.3 Å²	146.3	93%	0.926	83%	0.828	S	S	*	*			trans	-128.7	110.3	145	-84.7	-174.8	178.2	177.1	0	109.4
20	L	27.7	Very low	30.2	Very low	159 Å²	159	147.6 Å²	147.6	83%	0.832	82%	0.824	S	S	*	*			trans	-73.5	130.9	157.2	-86.2	119.6	0	0	0	108.4	L18	L18-L20 HydrophobicContact CD2-CD1 4.03Å
21	S	28.7	Very low	30	Very low	124 Å²	124	150.6 Å²	150.6	87%	0.867	82%	0.824	S	S	*	*			trans	-148.6	118.9	150.6	-160.4	0	0	0	0	107.7
22	G	26.8	Very low	29.6	Very low	67 Å²	67	143.7 Å²	143.7	69%	0.691	82%	0.815	S	S	*	*			trans	-89.9	157	-177.9	0	0	0	0	0	112.1
23	S	26.1	Very low	29.3	Very low	118 Å²	118	142.6 Å²	142.6	83%	0.825	81%	0.812	S	S	*	*			trans	-161.4	118.1	152.9	-43.4	0	0	0	0	108.4
24	Y	26.8	Very low	28.8	Very low	230 Å²	230	144.3 Å²	144.3	90%	0.902	81%	0.814	S	S	*	*			trans	-77.3	147.3	156.8	-86.4	-90.6	0	0	0	108.4
25	P	35.8	Very low	28.2	Very low	124 Å²	124	141.9 Å²	141.9	81%	0.805	81%	0.812	S	S	*	*				-140.7	152.1	100.6	29.1	-9.5	0	0	0	111.3
26	G	26.6	Very low	28.1	Very low	73 Å²	73	138 Å²	138	75%	0.753	81%	0.809	S	S	*	*				103	109.6	74.1	0	0	0	0	0	108.7
27	S	29.5	Very low	27.9	Very low	114 Å²	114	138.6 Å²	138.6	80%	0.797	81%	0.812	S	S	*	*			trans	-65.7	132.2	176.2	46.8	0	0	0	0	112.5
28	D	25.6	Very low	28.2	Very low	159 Å²	159	138.2 Å²	138.2	85%	0.85	81%	0.809	S	S	*	*			trans	-164.4	175.9	140.6	-117.1	-31.4	0	0	0	112.5
29	S	26.8	Very low	28.5	Very low	90 Å²	90	133.4 Å²	133.4	63%	0.629	79%	0.791	S	S	*	*			trans	-107.4	156.1	-132.9	29.5	0	0	0	0	116.1
30	S	25.4	Very low	28.9	Very low	106 Å²	106	127.3 Å²	127.3	74%	0.741	77%	0.774	S	S	*	*			trans	63.5	117.2	150.3	56.8	0	0	0	0	122.4
31	Q	27.2	Very low	29.5	Very low	185 Å²	185	125.4 Å²	125.4	86%	0.864	77%	0.771	S	S	*	*				169.8	133.7	112.6	-94	-179.6	-1.2	0	0	115.8
32	S	25	Very low	29.9	Very low	108 Å²	108	121.6 Å²	121.6	76%	0.755	75%	0.751	S	S	*	*			trans	50	118	147.4	82.3	0	0	0	0	125.3
33	M	28.9	Very low	30.4	Very low	167 Å²	167	124.2 Å²	124.2	82%	0.823	75%	0.748	S	S	*	*				38.7	113.9	122.3	-86.3	-168	149.1	0	0	121.5
34	N	28.4	Very low	31.2	Very low	155 Å²	155	124.2 Å²	124.2	83%	0.829	74%	0.738	S	S	*	*				152.9	123.5	109	-82	-28.6	0	0	0	111.4
35	G	26.6	Very low	32.1	Very low	75 Å²	75	117.5 Å²	117.5	77%	0.773	72%	0.721	S	S	*	*			trans	172.6	67	175.3	0	0	0	0	0	111.5	E37	G35-E37 VanDerWaalsContact C-N 3.3Å; G35-E37 PolarHBondContact O-N 3.02Å
36	L	29	Very low	32.3	Very low	164 Å²	164	117.3 Å²	117.3	86%	0.859	71%	0.714	S	S	*	*			trans	-76.8	84.1	171.5	-155.2	86.1	0	0	0	108	V38	L36-V38 HydrophobicContact CD2-CG2 4.45Å; L36-V38 PolarHBondContact O-N 3.45Å; L36-V38 VanDerWaalsContact O-N 3.1Å
37	E	28.8	Very low	32.9	Very low	192 Å²	192	121.3 Å²	121.3	90%	0.897	71%	0.71	S	S	*	*			trans	-66.9	105.5	163	-96.4	-173.9	125.7	0	0	108.1	G35 A39	G35-E37 VanDerWaalsContact C-N 3.3Å; G35-E37 PolarHBondContact O-N 3.02Å; E37-A39 PolarHBondContact O-N 3.41Å
38	V	35.7	Very low	33.8	Very low	125 Å²	125	118 Å²	118	76%	0.758	69%	0.688	S	S	*	*			trans	-68.6	100.9	170.9	177.9	0	0	0	0	107.5	L36	L36-V38 HydrophobicContact CD2-CG2 4.45Å; L36-V38 PolarHBondContact O-N 3.45Å; L36-V38 VanDerWaalsContact O-N 3.1Å
39	A	34.5	Very low	34.8	Very low	53 Å²	53	113.1 Å²	113.1	44%	0.438	66%	0.661	S	S	.	*			trans	-59	142.2	170.8	0	0	0	0	0	110.4	E37	E37-A39 PolarHBondContact O-N 3.41Å
40	P	36.6	Very low	35.4	Very low	86 Å²	86	110.9 Å²	110.9	56%	0.558	65%	0.648	S	S	*	*			trans	-65.5	154.2	-176	25.1	-32.4	0	0	0	111.9	G42 L43	P40-G42 PolarHBondContact O-N 3.04Å; P40-L43 PolarHBondContact O-N 3.25Å
41	P	40.9	Very low	36.3	Very low	119 Å²	119	109.4 Å²	109.4	77%	0.773	63%	0.634	S	S	*	*	T	Hydrogen-bonded Turn	trans	-62.8	-6.7	-169.6	-20.1	31.2	0	0	0	115.9
42	G	37.6	Very low	37.3	Very low	44 Å²	44	102.4 Å²	102.4	45%	0.454	61%	0.609	S	S	.	*	T	Hydrogen-bonded Turn	trans	-86.4	-16.9	-179.5	0	0	0	0	0	115.4	P40 T45	P40-G42 PolarHBondContact O-N 3.04Å; G42-T45 PolarHBondContact O-OG1 3.4Å
43	L	35.8	Very low	38.5	Very low	121 Å²	121	99.9 Å²	99.9	63%	0.634	59%	0.585	S	S	*	*	H	α-helix	trans	-85.7	-28.2	-175.9	-122.8	81.7	0	0	0	113.4	P40 F47	P40-L43 PolarHBondContact O-N 3.25Å; L43-F47 PolarHBondContact O-N 2.92Å
44	I	43.4	Very low	39.7	Very low	118 Å²	118	99.8 Å²	99.8	61%	0.605	58%	0.582	S	S	*	*	H	α-helix	trans	-74.2	-28.5	-175.4	-57.1	176.6	0	0	0	111.4	S48	I44-S48 PolarHBondContact O-OG 3.26Å
45	T	45.3	Very low	41.4	Very low	90 Å²	90	93.2 Å²	93.2	55%	0.552	55%	0.548	S	S	*	.	H	α-helix	trans	-76.7	-27.5	179	42.2	0	0	0	0	113.9	G42	G42-T45 PolarHBondContact O-OG1 3.4Å
46	N	41	Very low	43	Very low	120 Å²	120	91.4 Å²	91.4	64%	0.642	53%	0.529	S	S	*	.	H	α-helix	trans	-79.7	-33.7	177	-74	-11.8	0	0	0	111.8	S48 A50	N46-S48 PolarHBondContact O-N 3.4Å; N46-A50 WeakPolarHBondContact O-CB 3.43Å; N46-A50 PolarHBondContact O-N 3.47Å
47	F	39.4	Very low	44.7	Very low	156 Å²	156	91.5 Å²	91.5	68%	0.684	53%	0.525	S	S	*	.	H	α-helix	trans	-70.5	-32.8	-177.3	-156.2	-96.4	0	0	0	113.2	L43 T51	L43-F47 PolarHBondContact O-N 2.92Å; F47-T51 HydrophobicContact CD1-CG2 4.34Å; F47-T51 HydrophobicContact CE1-CG2 4.18Å; F47-T51 WeakPolarHBondContact O-CG2 3.4Å; F47-T51 PolarHBondContact O-N 3.45Å; F47-T51 PolarHBondContact O-OG1 3.41Å
48	S	47.3	Very low	46.9	Very low	46 Å²	46	84.2 Å²	84.2	32%	0.322	49%	0.491	S	S	.	.	H	α-helix	trans	-83.5	-18.5	-177.7	35	0	0	0	0	114.1	I44 N46 T51	I44-S48 PolarHBondContact O-OG 3.26Å; N46-S48 PolarHBondContact O-N 3.4Å; S48-T51 WeakPolarHBondContact CA-OG1 3.36Å; S48-T51 PolarHBondContact O-OG1 3.23Å
49	L	46.4	Very low	49.1	Very low	56 Å²	56	80.7 Å²	80.7	29%	0.293	47%	0.47	S	S	.	.	H	α-helix	trans	-85.6	-39	169.8	-141.4	91	0	0	0	111.5	T51 A52 V205	L49-T51 VanDerWaalsContact C-N 3.34Å; L49-T51 PolarHBondContact O-N 3.11Å; L49-A52 PolarHBondContact O-N 3.16Å; L49-V205 HydrophobicContact CD2-CB 4.43Å; L49-V205 HydrophobicContact CD2-CG1 3.73Å
50	A	40.8	Very low	51.6	Low	43 Å²	43	83.5 Å²	83.5	36%	0.355	48%	0.484	S	S	.	.	H	α-helix	trans	-64.9	-34.9	178.5	0	0	0	0	0	112.8	N46 A52 E53	N46-A50 WeakPolarHBondContact O-CB 3.43Å; N46-A50 PolarHBondContact O-N 3.47Å; A50-A52 VanDerWaalsContact C-N 3.31Å; A50-A52 PolarHBondContact O-N 3.39Å; A50-E53 WeakPolarHBondContact O-CB 3.35Å; A50-E53 PolarHBondContact O-N 3.15Å
51	T	43.2	Very low	54.2	Low	74 Å²	74	85 Å²	85	45%	0.454	49%	0.486	S	S	.	.	T	Hydrogen-bonded Turn	trans	-70.8	-23.4	179.2	38.3	0	0	0	0	113.9	F47 S48 L49 E53	F47-T51 HydrophobicContact CD1-CG2 4.34Å; F47-T51 HydrophobicContact CE1-CG2 4.18Å; F47-T51 WeakPolarHBondContact O-CG2 3.4Å; F47-T51 PolarHBondContact O-N 3.45Å; F47-T51 PolarHBondContact O-OG1 3.41Å; S48-T51 WeakPolarHBondContact CA-OG1 3.36Å; S48-T51 PolarHBondContact O-OG1 3.23Å; L49-T51 VanDerWaalsContact C-N 3.34Å; L49-T51 PolarHBondContact O-N 3.11Å; T51-E53 VanDerWaalsContact C-N 3.32Å
52	A	49.1	Very low	56.5	Low	39 Å²	39	81.2 Å²	81.2	32%	0.322	46%	0.458	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.6	-16.8	173.2	0	0	0	0	0	113	L49 A50	L49-A52 PolarHBondContact O-N 3.16Å; A50-A52 VanDerWaalsContact C-N 3.31Å; A50-A52 PolarHBondContact O-N 3.39Å
53	E	50.8	Low	59	Low	54 Å²	54	80 Å²	80	25%	0.252	44%	0.441	S	S	.	.	T	Hydrogen-bonded Turn	trans	-79.7	-23.5	-175.9	-73.4	-169.3	80.1	0	0	114.7	A50 T51 C55 T207 N208	A50-E53 WeakPolarHBondContact O-CB 3.35Å; A50-E53 PolarHBondContact O-N 3.15Å; T51-E53 VanDerWaalsContact C-N 3.32Å; E53-C55 PolarHBondContact O-N 2.96Å; E53-T207 HydrophobicContact CG-CG2 4.25Å; E53-T207 WeakPolarHBondContact OE1-CG2 3.29Å; E53-N208 PolarHBondContact OE1-ND2 3.33Å
54	Q	53.7	Low	61.7	Low	166 Å²	166	80 Å²	80	78%	0.776	44%	0.44	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.8	-4.4	176.5	-110.8	84.2	10.8	0	0	113.1	G56	Q54-G56 PolarHBondContact O-N 3.29Å; Q54-G56 VanDerWaalsContact O-N 3.15Å
55	C	63.6	Low	64.1	Low	17 Å²	17	79.6 Å²	79.6	12%	0.115	44%	0.438	C	S	.	.	S	Bend	trans	-94.1	61.7	-168.2	-70.3	0	0	0	0	115.9	E53 C301	E53-C55 PolarHBondContact O-N 2.96Å; C55-C301 WeakPolarHBondContact CA-SG 3.31Å; C55-C301 HydrophobicContact CB-CB 4.08Å; C55-C301 WeakPolarHBondContact CB-SG 3.44Å; C55-C301 WeakPolarHBondContact SG-CA 3.37Å; C55-C301 WeakPolarHBondContact SG-CB 3.46Å; C55-C301 CovalentContact SG-SG 2.03Å; C55-C301 PolarHBondContact SG-SG 3.2Å
56	G	59.7	Low	66.5	Low	36 Å²	36	76.3 Å²	76.3	37%	0.371	42%	0.417	S	S	.	.			trans	78.7	120.7	171.8	0	0	0	0	0	112.8	Q54	Q54-G56 PolarHBondContact O-N 3.29Å; Q54-G56 VanDerWaalsContact O-N 3.15Å
57	Q	64.9	Low	69	Low	166 Å²	166	70.6 Å²	70.6	78%	0.776	39%	0.386	S	S	*	.	P	Polyproline II helix	trans	-68.9	139.9	175.1	-67.9	-81.7	-43.4	0	0	110.2	R305	Q57-R305 PolarHBondContact O-NH2 2.66Å
58	E	74.6	Confident	71.6	Confident	40 Å²	40	66.1 Å²	66.1	19%	0.187	37%	0.374	C	S	.	.	P	Polyproline II helix	trans	-67.8	138.2	175.3	-57.6	179	-170.6	0	0	109.5	N127 R312	E58-N127 PolarHBondContact OE2-ND2 3.22Å; E58-N127 PolarHBondContact OE2-OD1 2.93Å; E58-N127 VanDerWaalsContact OE2-OD1 3.12Å; E58-R312 IonicContact OE1-CZ 3.3Å; E58-R312 IonicContact OE1-NH1 2.9Å; E58-R312 PolarHBondContact OE1-NH1 3.23Å; E58-R312 IonicContact OE1-NH2 3.93Å; E58-R312 PolarHBondContact OE1-NH2 3.27Å; E58-R312 IonicContact OE2-CZ 2.8Å; E58-R312 IonicContact OE2-NH1 2.72Å; E58-R312 PolarHBondContact OE2-NH1 3.14Å; E58-R312 IonicContact OE2-NH2 3.25Å
59	T	83.3	Confident	74	Confident	50 Å²	50	66.7 Å²	66.7	31%	0.307	37%	0.371	S	S	.	.	P	Polyproline II helix	trans	-83.7	147.4	-175.4	63.7	0	0	0	0	111.2	L61 E62 N63	T59-L61 PolarHBondContact O-N 2.94Å; T59-E62 WeakPolarHBondContact O-CB 3.29Å; T59-E62 PolarHBondContact O-N 3.42Å; T59-E62 VanDerWaalsContact O-N 3.08Å; T59-E62 WeakPolarHBondContact OG1-CB 3.38Å; T59-E62 VanDerWaalsContact OG1-CD 3.28Å; T59-E62 WeakPolarHBondContact OG1-CG 3.5Å; T59-E62 PolarHBondContact OG1-N 3.21Å; T59-E62 PolarHBondContact OG1-OE1 3.41Å; T59-N63 PolarHBondContact O-N 2.92Å
60	P	86.5	Confident	76.3	Confident	113 Å²	113	64.1 Å²	64.1	73%	0.734	36%	0.357	S	S	*	.	H	α-helix	trans	-55.8	-32.7	173.1	-26.2	34.6	0	0	0	112.8	N63 M64	P60-N63 PolarHBondContact O-N 3.05Å; P60-M64 WeakPolarHBondContact O-CB 3.35Å; P60-M64 PolarHBondContact O-N 3.27Å
61	L	90.1	Very high	79	Confident	116 Å²	116	65.9 Å²	65.9	61%	0.607	36%	0.36	S	S	*	.	H	α-helix	trans	-64.8	-46.2	175.5	-179	62.4	0	0	0	112	T59 N63 M64 L65	T59-L61 PolarHBondContact O-N 2.94Å; L61-N63 VanDerWaalsContact C-N 3.33Å; L61-N63 PolarHBondContact O-N 3.23Å; L61-M64 PolarHBondContact O-N 2.79Å; L61-L65 HydrophobicContact CD1-CG 4.45Å; L61-L65 HydrophobicContact CG-CD1 4.3Å; L61-L65 WeakPolarHBondContact O-CG 3.29Å; L61-L65 PolarHBondContact O-N 3.34Å
62	E	90	Very high	81.5	Confident	40 Å²	40	67.2 Å²	67.2	19%	0.187	36%	0.364	C	S	.	.	H	α-helix	trans	-55.7	-48.6	175.3	-78.7	163	-129.9	0	0	111	T59 M64 L65 F66 R305	T59-E62 WeakPolarHBondContact O-CB 3.29Å; T59-E62 PolarHBondContact O-N 3.42Å; T59-E62 VanDerWaalsContact O-N 3.08Å; T59-E62 WeakPolarHBondContact OG1-CB 3.38Å; T59-E62 VanDerWaalsContact OG1-CD 3.28Å; T59-E62 WeakPolarHBondContact OG1-CG 3.5Å; T59-E62 PolarHBondContact OG1-N 3.21Å; T59-E62 PolarHBondContact OG1-OE1 3.41Å; E62-M64 VanDerWaalsContact C-N 3.34Å; E62-M64 PolarHBondContact O-N 2.93Å; E62-L65 PolarHBondContact O-N 2.95Å; E62-F66 HydrophobicContact CB-CE2 4.37Å; E62-F66 WeakPolarHBondContact O-CD2 3.14Å; E62-F66 PolarHBondContact O-N 3.24Å; E62-R305 IonicContact OE1-NH2 3.14Å
63	N	90.5	Very high	83.8	Confident	18 Å²	18	65.4 Å²	65.4	10%	0.096	35%	0.349	C	S	.	.	H	α-helix	trans	-60.7	-42	179	-72.4	-11.2	0	0	0	112.2	T59 P60 L61 L65 F66 A67	T59-N63 PolarHBondContact O-N 2.92Å; P60-N63 PolarHBondContact O-N 3.05Å; L61-N63 VanDerWaalsContact C-N 3.33Å; L61-N63 PolarHBondContact O-N 3.23Å; N63-L65 VanDerWaalsContact C-N 3.35Å; N63-L65 PolarHBondContact O-N 3.39Å; N63-F66 PolarHBondContact O-N 3.38Å; N63-A67 WeakPolarHBondContact O-CB 3.39Å; N63-A67 PolarHBondContact O-N 3.11Å
64	M	92.4	Very high	86	Confident	122 Å²	122	65.9 Å²	65.9	60%	0.601	35%	0.35	S	S	*	.	H	α-helix	trans	-65	-37.3	177.3	-175.8	168.1	157.5	0	0	112.5	P60 L61 E62 S68	P60-M64 WeakPolarHBondContact O-CB 3.35Å; P60-M64 PolarHBondContact O-N 3.27Å; L61-M64 PolarHBondContact O-N 2.79Å; E62-M64 VanDerWaalsContact C-N 3.34Å; E62-M64 PolarHBondContact O-N 2.93Å; M64-S68 WeakPolarHBondContact O-CB 3.49Å; M64-S68 PolarHBondContact O-N 3.42Å; M64-S68 PolarHBondContact O-OG 3.27Å
65	L	94.3	Very high	88	Confident	109 Å²	109	62 Å²	62	57%	0.571	33%	0.334	S	S	*	.	H	α-helix	trans	-66.9	-46.8	175.6	-69.5	173.1	0	0	0	111.6	L61 E62 N63 S68 F69	L61-L65 HydrophobicContact CD1-CG 4.45Å; L61-L65 HydrophobicContact CG-CD1 4.3Å; L61-L65 WeakPolarHBondContact O-CG 3.29Å; L61-L65 PolarHBondContact O-N 3.34Å; E62-L65 PolarHBondContact O-N 2.95Å; N63-L65 VanDerWaalsContact C-N 3.35Å; N63-L65 PolarHBondContact O-N 3.39Å; L65-S68 PolarHBondContact O-N 3.34Å; L65-F69 WeakPolarHBondContact O-CB 3.42Å; L65-F69 PolarHBondContact O-N 3.3Å
66	F	94	Very high	89.5	Confident	22 Å²	22	65.2 Å²	65.2	10%	0.096	35%	0.35	C	S	.	.	H	α-helix	trans	-65	-41	177.4	-72.9	-60.7	0	0	0	112.3	E62 N63 F69 Y70 H123 L309 R312 I313 C316	E62-F66 HydrophobicContact CB-CE2 4.37Å; E62-F66 WeakPolarHBondContact O-CD2 3.14Å; E62-F66 PolarHBondContact O-N 3.24Å; N63-F66 PolarHBondContact O-N 3.38Å; F66-F69 PolarHBondContact O-N 2.86Å; F66-Y70 WeakPolarHBondContact O-CD2 3.37Å; F66-Y70 PolarHBondContact O-N 3.27Å; F66-H123 AromaticContact CG-CE1 3.97Å; F66-L309 HydrophobicContact CE2-CD1 4.24Å; F66-L309 HydrophobicContact CZ-CD1 3.99Å; F66-R312 HydrophobicContact CD1-CB 4.49Å; F66-R312 HydrophobicContact CE1-CB 3.75Å; F66-R312 HydrophobicContact CE2-CB 4.11Å; F66-R312 HydrophobicContact CZ-CB 3.54Å; F66-R312 HydrophobicContact CZ-CG 4.39Å; F66-I313 HydrophobicContact CE1-CG1 4.3Å; F66-I313 HydrophobicContact CZ-CG1 4.14Å; F66-C316 VanDerWaalsContact CD1-SG 3.54Å
67	A	93.9	Very high	91.2	Very high	0 Å²	0	63.7 Å²	63.7	0%	0	33%	0.333	C	S	.	.	H	α-helix	trans	-58.3	-51	173.3	0	0	0	0	0	111.3	N63 F69 Y70 L71 L120 H123 F124	N63-A67 WeakPolarHBondContact O-CB 3.39Å; N63-A67 PolarHBondContact O-N 3.11Å; A67-F69 VanDerWaalsContact C-N 3.28Å; A67-F69 PolarHBondContact O-N 3.47Å; A67-Y70 PolarHBondContact O-N 3.04Å; A67-L71 PolarHBondContact O-N 3.5Å; A67-L120 HydrophobicContact CB-CD1 3.71Å; A67-L120 WeakPolarHBondContact O-CD1 3.28Å; A67-H123 HydrophobicContact CB-CB 4.13Å; A67-F124 HydrophobicContact CB-CD2 4Å; A67-F124 HydrophobicContact CB-CE1 4.45Å; A67-F124 HydrophobicContact CB-CE2 3.83Å; A67-F124 HydrophobicContact CB-CG 4.4Å; A67-F124 HydrophobicContact CB-CZ 4.06Å
68	S	95.4	Very high	92.7	Very high	62 Å²	62	60.5 Å²	60.5	43%	0.434	32%	0.317	S	S	.	.	H	α-helix	trans	-59.2	-40.2	178.9	-58	0	0	0	0	112.2	M64 L65 L72	M64-S68 WeakPolarHBondContact O-CB 3.49Å; M64-S68 PolarHBondContact O-N 3.42Å; M64-S68 PolarHBondContact O-OG 3.27Å; L65-S68 PolarHBondContact O-N 3.34Å; S68-L72 PolarHBondContact O-N 3.31Å; S68-L72 VanDerWaalsContact O-N 3.11Å
69	F	96.1	Very high	93.6	Very high	58 Å²	58	62.9 Å²	62.9	25%	0.254	33%	0.334	S	S	.	.	H	α-helix	trans	-60.1	-53.3	174.8	175.3	-87.4	0	0	0	111.9	L65 F66 A67 L71 L72 D73 C316 L320	L65-F69 WeakPolarHBondContact O-CB 3.42Å; L65-F69 PolarHBondContact O-N 3.3Å; F66-F69 PolarHBondContact O-N 2.86Å; A67-F69 VanDerWaalsContact C-N 3.28Å; A67-F69 PolarHBondContact O-N 3.47Å; F69-L71 VanDerWaalsContact C-N 3.27Å; F69-L71 PolarHBondContact O-N 3.02Å; F69-L72 PolarHBondContact O-N 2.86Å; F69-L72 VanDerWaalsContact O-N 3.16Å; F69-D73 HydrophobicContact CE1-CB 4.2Å; F69-D73 WeakPolarHBondContact O-CB 3.49Å; F69-D73 PolarHBondContact O-N 2.92Å; F69-C316 HydrophobicContact CD1-CB 3.74Å; F69-C316 HydrophobicContact CE1-CB 3.38Å; F69-C316 WeakPolarHBondContact CE1-O 3.39Å; F69-C316 HydrophobicContact CE2-CB 4.34Å; F69-C316 HydrophobicContact CG-CB 4.38Å; F69-C316 HydrophobicContact CZ-CB 3.72Å; F69-C316 WeakPolarHBondContact CZ-O 3.49Å; F69-L320 HydrophobicContact CE2-CD1 4.24Å; F69-L320 HydrophobicContact CZ-CB 4.25Å; F69-L320 HydrophobicContact CZ-CD1 4.14Å
70	Y	95.9	Very high	94.1	Very high	1 Å²	1	61 Å²	61	0%	0.004	32%	0.324	C	S	.	.	H	α-helix	trans	-65.8	-29.9	-177.7	-74.3	-57.7	0	0	0	113	F66 A67 F74 L116 R119 H123 Y217 C316	F66-Y70 WeakPolarHBondContact O-CD2 3.37Å; F66-Y70 PolarHBondContact O-N 3.27Å; A67-Y70 PolarHBondContact O-N 3.04Å; Y70-F74 WeakPolarHBondContact O-CB 3.41Å; Y70-F74 PolarHBondContact O-N 3.4Å; Y70-L116 HydrophobicContact CD1-CD2 3.99Å; Y70-L116 HydrophobicContact CE1-CD2 4.38Å; Y70-R119 HydrophobicContact CD1-CB 4.3Å; Y70-R119 HydrophobicContact CD2-CB 3.86Å; Y70-R119 HydrophobicContact CE1-CB 4.37Å; Y70-R119 HydrophobicContact CE2-CB 3.93Å; Y70-R119 HydrophobicContact CG-CB 4.06Å; Y70-H123 AromaticContact CD2-CD2 3.87Å; Y70-H123 AromaticContact CE2-CD2 3.76Å; Y70-H123 AromaticContact CE2-NE2 3.66Å; Y70-Y217 VanDerWaalsContact CE2-OH 3.28Å; Y70-Y217 WeakPolarHBondContact CE2-OH 3.36Å; Y70-Y217 PolarHBondContact OH-OH 2.97Å; Y70-C316 PolarHBondContact OH-SG 2.98Å; Y70-C316 VanDerWaalsContact OH-SG 3.34Å
71	L	96.6	Very high	94.5	Very high	81 Å²	81	55.6 Å²	55.6	42%	0.424	29%	0.289	S	S	.	.	H	α-helix	trans	-65	-47.1	172.1	178.5	62.1	0	0	0	111.5	A67 F69 F74 I75 L120	A67-L71 PolarHBondContact O-N 3.5Å; F69-L71 VanDerWaalsContact C-N 3.27Å; F69-L71 PolarHBondContact O-N 3.02Å; L71-F74 PolarHBondContact O-N 3.49Å; L71-I75 HydrophobicContact CD1-CD1 4.3Å; L71-I75 HydrophobicContact CG-CD1 4.31Å; L71-I75 WeakPolarHBondContact O-CG1 3.21Å; L71-I75 PolarHBondContact O-N 2.9Å; L71-I75 VanDerWaalsContact O-N 3.14Å; L71-L120 HydrophobicContact CB-CD1 4.16Å; L71-L120 HydrophobicContact CB-CD2 4.37Å; L71-L120 HydrophobicContact CD1-CD2 4.2Å
72	L	96.5	Very high	94.7	Very high	101 Å²	101	52.8 Å²	52.8	53%	0.529	28%	0.277	S	S	.	.	H	α-helix	trans	-64.2	-45.9	177.8	179.6	62.6	0	0	0	111.3	S68 F69 F74 I75 L76	S68-L72 PolarHBondContact O-N 3.31Å; S68-L72 VanDerWaalsContact O-N 3.11Å; F69-L72 PolarHBondContact O-N 2.86Å; F69-L72 VanDerWaalsContact O-N 3.16Å; L72-F74 VanDerWaalsContact C-N 3.31Å; L72-F74 PolarHBondContact O-N 3.43Å; L72-I75 PolarHBondContact O-N 3.26Å; L72-L76 HydrophobicContact CD1-CD1 4.03Å; L72-L76 HydrophobicContact CD1-CG 4.14Å; L72-L76 HydrophobicContact CG-CD1 3.94Å; L72-L76 HydrophobicContact CG-CG 4.42Å; L72-L76 WeakPolarHBondContact O-CG 3.4Å; L72-L76 PolarHBondContact O-N 3.4Å
73	D	96.1	Very high	94.8	Very high	2 Å²	2	52.8 Å²	52.8	1%	0.011	28%	0.278	C	S	.	.	H	α-helix	trans	-58.6	-44.4	178	-165.2	24.9	0	0	0	110.9	F69 I75 L76 A77 L116 S319 A323	F69-D73 HydrophobicContact CE1-CB 4.2Å; F69-D73 WeakPolarHBondContact O-CB 3.49Å; F69-D73 PolarHBondContact O-N 2.92Å; D73-I75 PolarHBondContact O-N 3.38Å; D73-L76 PolarHBondContact O-N 2.92Å; D73-A77 WeakPolarHBondContact O-CB 3.41Å; D73-A77 PolarHBondContact O-N 3.16Å; D73-L116 HydrophobicContact CB-CD1 4.35Å; D73-S319 WeakPolarHBondContact OD2-CB 3.33Å; D73-S319 PolarHBondContact OD2-OG 3.34Å; D73-A323 WeakPolarHBondContact OD1-CB 3.3Å
74	F	97.2	Very high	94.8	Very high	63 Å²	63	51.9 Å²	51.9	28%	0.276	27%	0.274	S	S	.	.	H	α-helix	trans	-56.1	-50.3	174.4	169.7	-99.4	0	0	0	112.6	Y70 L71 L72 F78 V113 L116 P117	Y70-F74 WeakPolarHBondContact O-CB 3.41Å; Y70-F74 PolarHBondContact O-N 3.4Å; L71-F74 PolarHBondContact O-N 3.49Å; L72-F74 VanDerWaalsContact C-N 3.31Å; L72-F74 PolarHBondContact O-N 3.43Å; F74-F78 WeakPolarHBondContact O-CB 3.22Å; F74-F78 PolarHBondContact O-N 3.4Å; F74-V113 HydrophobicContact CD2-CG1 3.65Å; F74-V113 HydrophobicContact CE2-CG1 3.53Å; F74-L116 HydrophobicContact CB-CB 4.08Å; F74-L116 HydrophobicContact CB-CD1 4.16Å; F74-L116 HydrophobicContact CD2-CB 4.49Å; F74-P117 HydrophobicContact CD2-CG 3.76Å; F74-P117 HydrophobicContact CE2-CG 3.79Å
75	I	96.3	Very high	94.8	Very high	85 Å²	85	47.6 Å²	47.6	44%	0.436	25%	0.253	S	S	.	.	H	α-helix	trans	-62.2	-48.8	-178.2	-66.1	165.9	0	0	0	110.3	L71 L72 D73 V79	L71-I75 HydrophobicContact CD1-CD1 4.3Å; L71-I75 HydrophobicContact CG-CD1 4.31Å; L71-I75 WeakPolarHBondContact O-CG1 3.21Å; L71-I75 PolarHBondContact O-N 2.9Å; L71-I75 VanDerWaalsContact O-N 3.14Å; L72-I75 PolarHBondContact O-N 3.26Å; D73-I75 PolarHBondContact O-N 3.38Å; I75-V79 WeakPolarHBondContact O-CB 3.38Å; I75-V79 VanDerWaalsContact O-CG2 3.28Å; I75-V79 WeakPolarHBondContact O-CG2 3.21Å; I75-V79 PolarHBondContact O-N 2.7Å; I75-V79 VanDerWaalsContact O-N 3.07Å
76	L	94.9	Very high	94.7	Very high	85 Å²	85	48.9 Å²	48.9	45%	0.445	25%	0.25	S	S	.	.	H	α-helix	trans	-65.1	-49.6	-177.3	-67.1	177.1	0	0	0	111.7	L72 D73 G80 A323	L72-L76 HydrophobicContact CD1-CD1 4.03Å; L72-L76 HydrophobicContact CD1-CG 4.14Å; L72-L76 HydrophobicContact CG-CD1 3.94Å; L72-L76 HydrophobicContact CG-CG 4.42Å; L72-L76 WeakPolarHBondContact O-CG 3.4Å; L72-L76 PolarHBondContact O-N 3.4Å; D73-L76 PolarHBondContact O-N 2.92Å; L76-G80 PolarHBondContact O-N 3.41Å; L76-A323 HydrophobicContact CB-CB 3.84Å; L76-A323 HydrophobicContact CD1-CB 4.46Å
77	A	95.7	Very high	94.5	Very high	3 Å²	3	49 Å²	49	3%	0.025	25%	0.251	C	S	.	.	H	α-helix	trans	-65.4	-43	-179.3	0	0	0	0	0	111.6	D73 N81 V113 A323	D73-A77 WeakPolarHBondContact O-CB 3.41Å; D73-A77 PolarHBondContact O-N 3.16Å; A77-N81 VanDerWaalsContact O-CB 3.26Å; A77-N81 WeakPolarHBondContact O-CB 3.35Å; A77-N81 PolarHBondContact O-N 3.03Å; A77-N81 PolarHBondContact O-ND2 3.03Å; A77-V113 HydrophobicContact CB-CG2 3.73Å; A77-A323 HydrophobicContact CB-CB 4.48Å
78	F	96.3	Very high	94.1	Very high	100 Å²	100	49.9 Å²	49.9	44%	0.439	26%	0.256	S	S	.	.	H	α-helix	trans	-63.6	-53.4	179.2	179.9	-110.9	0	0	0	111.8	F74 T82 L110 V113	F74-F78 WeakPolarHBondContact O-CB 3.22Å; F74-F78 PolarHBondContact O-N 3.4Å; F78-T82 WeakPolarHBondContact O-CB 3.41Å; F78-T82 PolarHBondContact O-N 3.34Å; F78-T82 PolarHBondContact O-OG1 3.14Å; F78-L110 HydrophobicContact CD2-CD2 4.35Å; F78-V113 HydrophobicContact CB-CG1 3.89Å; F78-V113 HydrophobicContact CB-CG2 4.45Å; F78-V113 HydrophobicContact CD2-CG1 3.9Å; F78-V113 HydrophobicContact CG-CG1 4.31Å
79	V	94.2	Very high	93.8	Very high	89 Å²	89	51.4 Å²	51.4	54%	0.539	26%	0.258	S	S	.	.	H	α-helix	trans	-64.3	-47.3	-177.5	174.3	0	0	0	0	110.6	I75 L83	I75-V79 WeakPolarHBondContact O-CB 3.38Å; I75-V79 VanDerWaalsContact O-CG2 3.28Å; I75-V79 WeakPolarHBondContact O-CG2 3.21Å; I75-V79 PolarHBondContact O-N 2.7Å; I75-V79 VanDerWaalsContact O-N 3.07Å; V79-L83 WeakPolarHBondContact O-CB 3.41Å; V79-L83 PolarHBondContact O-N 3.42Å; V79-L83 VanDerWaalsContact O-N 3.1Å
80	G	92.6	Very high	93.2	Very high	10 Å²	10	57.1 Å²	57.1	10%	0.103	28%	0.278	C	S	.	.	H	α-helix	trans	-63.4	-51.2	-177	0	0	0	0	0	113	L76 A84	L76-G80 PolarHBondContact O-N 3.41Å; G80-A84 WeakPolarHBondContact O-CB 3.34Å; G80-A84 PolarHBondContact O-N 3.46Å
81	N	95.2	Very high	92.4	Very high	0 Å²	0	57.8 Å²	57.8	0%	0	28%	0.281	C	S	.	.	H	α-helix	trans	-74.8	-32.4	-176.9	-68	-70	0	0	0	112.7	A77 A84 L85 A106 D109 L110 G322 Y329	A77-N81 VanDerWaalsContact O-CB 3.26Å; A77-N81 WeakPolarHBondContact O-CB 3.35Å; A77-N81 PolarHBondContact O-N 3.03Å; A77-N81 PolarHBondContact O-ND2 3.03Å; N81-A84 PolarHBondContact O-N 3.33Å; N81-L85 VanDerWaalsContact O-CB 3.28Å; N81-L85 WeakPolarHBondContact O-CB 3.36Å; N81-L85 PolarHBondContact O-N 2.87Å; N81-A106 HydrophobicContact CB-CB 4.4Å; N81-D109 HydrophobicContact CB-CB 4.39Å; N81-D109 PolarHBondContact OD1-OD2 2.91Å; N81-L110 HydrophobicContact CB-CD2 3.92Å; N81-L110 HydrophobicContact CB-CG 3.86Å; N81-G322 PolarHBondContact ND2-O 3.11Å; N81-Y329 VanDerWaalsContact OD1-CE2 3.25Å; N81-Y329 WeakPolarHBondContact OD1-CE2 3.43Å; N81-Y329 PolarHBondContact OD1-OH 3.06Å
82	T	94.8	Very high	90.8	Very high	57 Å²	57	62.2 Å²	62.2	35%	0.35	30%	0.299	S	S	.	.	H	α-helix	trans	-64.9	-46.1	174.2	-58.4	0	0	0	0	111	F78 A84 L85 W86 L110	F78-T82 WeakPolarHBondContact O-CB 3.41Å; F78-T82 PolarHBondContact O-N 3.34Å; F78-T82 PolarHBondContact O-OG1 3.14Å; T82-A84 VanDerWaalsContact C-N 3.32Å; T82-A84 PolarHBondContact O-N 3Å; T82-L85 PolarHBondContact O-N 3.33Å; T82-W86 WeakPolarHBondContact O-CB 3.44Å; T82-W86 PolarHBondContact O-N 3.25Å; T82-L110 WeakPolarHBondContact OG1-CD2 3.34Å
83	L	92.1	Very high	88.9	Confident	40 Å²	40	67.1 Å²	67.1	21%	0.209	32%	0.316	C	S	.	.	H	α-helix	trans	-61.2	-42.9	176	178	61.8	0	0	0	111.2	V79 W86 L87 F336 L343	V79-L83 WeakPolarHBondContact O-CB 3.41Å; V79-L83 PolarHBondContact O-N 3.42Å; V79-L83 VanDerWaalsContact O-N 3.1Å; L83-W86 HydrophobicContact CD1-CE3 4.32Å; L83-L87 HydrophobicContact CD1-CD1 4.1Å; L83-L87 HydrophobicContact CD1-CG 4.31Å; L83-L87 HydrophobicContact CG-CD1 4.15Å; L83-L87 VanDerWaalsContact O-CG 3.31Å; L83-L87 WeakPolarHBondContact O-CG 3.27Å; L83-L87 PolarHBondContact O-N 3.24Å; L83-F336 HydrophobicContact CB-CE2 4.47Å; L83-F336 HydrophobicContact CD2-CE2 4.27Å; L83-F336 HydrophobicContact CG-CE2 4.16Å; L83-L343 HydrophobicContact CD2-CD1 3.9Å
84	A	91.2	Very high	87.1	Confident	0 Å²	0	68.5 Å²	68.5	0%	0	33%	0.326	C	S	.	.	H	α-helix	trans	-61.4	-52.2	178.3	0	0	0	0	0	111.8	G80 N81 T82 W86 L87 F88 Y329 F336	G80-A84 WeakPolarHBondContact O-CB 3.34Å; G80-A84 PolarHBondContact O-N 3.46Å; N81-A84 PolarHBondContact O-N 3.33Å; T82-A84 VanDerWaalsContact C-N 3.32Å; T82-A84 PolarHBondContact O-N 3Å; A84-W86 VanDerWaalsContact C-N 3.32Å; A84-W86 PolarHBondContact O-N 3.35Å; A84-L87 PolarHBondContact O-N 2.9Å; A84-F88 HydrophobicContact CB-CD2 4.37Å; A84-F88 HydrophobicContact CB-CE2 3.98Å; A84-F88 WeakPolarHBondContact O-CD2 3.38Å; A84-F88 WeakPolarHBondContact O-CG 3.48Å; A84-F88 PolarHBondContact O-N 3.43Å; A84-Y329 HydrophobicContact CB-CD2 3.27Å; A84-Y329 HydrophobicContact CB-CE2 3.47Å; A84-Y329 VanDerWaalsContact CB-CE2 3.47Å; A84-Y329 HydrophobicContact CB-CG 4.05Å; A84-F336 HydrophobicContact CB-CD2 3.84Å; A84-F336 HydrophobicContact CB-CE2 3.6Å
85	L	92.6	Very high	85.7	Confident	32 Å²	32	67.3 Å²	67.3	17%	0.168	33%	0.332	C	S	.	.	H	α-helix	trans	-59.9	-43.5	179.9	-175.5	58.7	0	0	0	111.4	N81 T82 L87 F88 I89 M103 A106 V107 L110	N81-L85 VanDerWaalsContact O-CB 3.28Å; N81-L85 WeakPolarHBondContact O-CB 3.36Å; N81-L85 PolarHBondContact O-N 2.87Å; T82-L85 PolarHBondContact O-N 3.33Å; L85-L87 VanDerWaalsContact C-N 3.35Å; L85-L87 PolarHBondContact O-N 3.44Å; L85-F88 PolarHBondContact O-N 3.41Å; L85-I89 HydrophobicContact CD1-CD1 3.94Å; L85-I89 HydrophobicContact CD1-CG1 4.2Å; L85-I89 HydrophobicContact CG-CD1 3.83Å; L85-I89 HydrophobicContact CG-CG1 4.49Å; L85-I89 VanDerWaalsContact O-CG1 3.29Å; L85-I89 WeakPolarHBondContact O-CG1 3.09Å; L85-I89 PolarHBondContact O-N 2.84Å; L85-M103 HydrophobicContact CD1-CG 3.58Å; L85-A106 HydrophobicContact CB-CB 4.32Å; L85-V107 HydrophobicContact CD1-CG2 4Å; L85-V107 HydrophobicContact CD2-CG2 4.09Å; L85-L110 HydrophobicContact CB-CD1 4.35Å; L85-L110 HydrophobicContact CD2-CD1 3.55Å
86	W	91.3	Very high	85.1	Confident	136 Å²	136	66.2 Å²	66.2	52%	0.515	33%	0.329	S	S	.	.	H	α-helix	trans	-59	-44.2	175.9	179.9	78.9	0	0	0	112.6	T82 L83 A84 R90	T82-W86 WeakPolarHBondContact O-CB 3.44Å; T82-W86 PolarHBondContact O-N 3.25Å; L83-W86 HydrophobicContact CD1-CE3 4.32Å; A84-W86 VanDerWaalsContact C-N 3.32Å; A84-W86 PolarHBondContact O-N 3.35Å; W86-R90 WeakPolarHBondContact O-CB 3.4Å; W86-R90 PolarHBondContact O-N 2.93Å; W86-R90 VanDerWaalsContact O-N 3.08Å
87	L	88.8	Confident	84.7	Confident	23 Å²	23	62.7 Å²	62.7	12%	0.12	31%	0.312	C	S	.	.	H	α-helix	trans	-68.2	-37.7	177.8	-71.1	173.8	0	0	0	112.6	L83 A84 L85 D91 F336 A339	L83-L87 HydrophobicContact CD1-CD1 4.1Å; L83-L87 HydrophobicContact CD1-CG 4.31Å; L83-L87 HydrophobicContact CG-CD1 4.15Å; L83-L87 VanDerWaalsContact O-CG 3.31Å; L83-L87 WeakPolarHBondContact O-CG 3.27Å; L83-L87 PolarHBondContact O-N 3.24Å; A84-L87 PolarHBondContact O-N 2.9Å; L85-L87 VanDerWaalsContact C-N 3.35Å; L85-L87 PolarHBondContact O-N 3.44Å; L87-D91 VanDerWaalsContact O-CB 3.28Å; L87-D91 WeakPolarHBondContact O-CB 3.2Å; L87-D91 PolarHBondContact O-N 3.28Å; L87-D91 VanDerWaalsContact O-N 3.11Å; L87-F336 HydrophobicContact CD1-CB 4.35Å; L87-F336 HydrophobicContact CD1-CD2 3.88Å; L87-F336 HydrophobicContact CD1-CG 4.46Å; L87-A339 HydrophobicContact CD1-CB 3.45Å; L87-A339 VanDerWaalsContact CD1-CB 3.45Å; L87-A339 HydrophobicContact CD2-CB 4.1Å; L87-A339 HydrophobicContact CG-CB 4.45Å
88	F	87.3	Confident	84.3	Confident	20 Å²	20	62.5 Å²	62.5	9%	0.088	31%	0.31	C	S	.	.	H	α-helix	trans	-66.3	-44.8	176.9	-68.5	-45.2	0	0	0	112.1	A84 L85 R90 D91 L102 M103 Y329 A333	A84-F88 HydrophobicContact CB-CD2 4.37Å; A84-F88 HydrophobicContact CB-CE2 3.98Å; A84-F88 WeakPolarHBondContact O-CD2 3.38Å; A84-F88 WeakPolarHBondContact O-CG 3.48Å; A84-F88 PolarHBondContact O-N 3.43Å; L85-F88 PolarHBondContact O-N 3.41Å; F88-R90 PolarHBondContact O-N 2.96Å; F88-D91 PolarHBondContact O-N 3.39Å; F88-L102 HydrophobicContact CE2-CB 3.94Å; F88-L102 HydrophobicContact CZ-CB 3.82Å; F88-L102 HydrophobicContact CZ-CD1 4.1Å; F88-M103 HydrophobicContact CB-CB 4.38Å; F88-M103 HydrophobicContact CB-CG 4.27Å; F88-M103 HydrophobicContact CD2-CB 4.37Å; F88-Y329 HydrophobicContact CE2-CD1 4.14Å; F88-Y329 HydrophobicContact CE2-CE1 4.33Å; F88-Y329 HydrophobicContact CE2-CG 4.44Å; F88-Y329 HydrophobicContact CZ-CD1 4.09Å; F88-Y329 HydrophobicContact CZ-CG 4.39Å; F88-A333 HydrophobicContact CE1-CB 3.51Å; F88-A333 HydrophobicContact CZ-CB 3.86Å
89	I	87.4	Confident	83.9	Confident	93 Å²	93	58.9 Å²	58.9	48%	0.477	30%	0.295	S	S	.	.	H	α-helix	trans	-63	-43.7	177.8	-67.9	168.3	0	0	0	110.6	L85 D91 H92	L85-I89 HydrophobicContact CD1-CD1 3.94Å; L85-I89 HydrophobicContact CD1-CG1 4.2Å; L85-I89 HydrophobicContact CG-CD1 3.83Å; L85-I89 HydrophobicContact CG-CG1 4.49Å; L85-I89 VanDerWaalsContact O-CG1 3.29Å; L85-I89 WeakPolarHBondContact O-CG1 3.09Å; L85-I89 PolarHBondContact O-N 2.84Å; I89-D91 PolarHBondContact O-N 2.94Å; I89-H92 PolarHBondContact O-NE2 2.74Å
90	R	85.3	Confident	83.8	Confident	178 Å²	178	55 Å²	55	67%	0.672	27%	0.272	S	S	*	.	H	α-helix	trans	-68.7	-22.2	-179.9	-167.9	171.7	178.9	154.4	3.6	112.9	W86 F88 H92	W86-R90 WeakPolarHBondContact O-CB 3.4Å; W86-R90 PolarHBondContact O-N 2.93Å; W86-R90 VanDerWaalsContact O-N 3.08Å; F88-R90 PolarHBondContact O-N 2.96Å; R90-H92 PolarHBondContact O-N 3.3Å
91	D	77.2	Confident	83.8	Confident	16 Å²	16	55.2 Å²	55.2	9%	0.086	27%	0.27	C	S	.	.			trans	-92.9	63.2	-179.6	-169.2	14.8	0	0	0	113.6	L87 F88 I89 K93 S94 K335	L87-D91 VanDerWaalsContact O-CB 3.28Å; L87-D91 WeakPolarHBondContact O-CB 3.2Å; L87-D91 PolarHBondContact O-N 3.28Å; L87-D91 VanDerWaalsContact O-N 3.11Å; F88-D91 PolarHBondContact O-N 3.39Å; I89-D91 PolarHBondContact O-N 2.94Å; D91-K93 PolarHBondContact O-N 2.97Å; D91-K93 PolarHBondContact OD1-N 3.48Å; D91-S94 PolarHBondContact O-N 3.13Å; D91-S94 WeakPolarHBondContact OD2-CB 3.47Å; D91-S94 PolarHBondContact OD2-OG 2.92Å; D91-K335 HydrophobicContact CB-CD 3.98Å; D91-K335 VanDerWaalsContact CG-CD 3.46Å; D91-K335 VanDerWaalsContact OD1-CE 3.28Å; D91-K335 WeakPolarHBondContact OD1-CE 3.49Å; D91-K335 IonicContact OD1-NZ 2.7Å; D91-K335 PolarHBondContact OD1-NZ 3.12Å; D91-K335 WeakPolarHBondContact OD2-CD 3.14Å; D91-K335 WeakPolarHBondContact OD2-CE 3.28Å; D91-K335 IonicContact OD2-NZ 3.67Å; D91-K335 PolarHBondContact OD2-NZ 3.42Å
92	H	63.1	Low	83.6	Confident	173 Å²	173	55.2 Å²	55.2	80%	0.801	27%	0.27	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.3	-15.6	175.9	-70.4	-77.7	0	0	0	114.6	I89 R90	I89-H92 PolarHBondContact O-NE2 2.74Å; R90-H92 PolarHBondContact O-N 3.3Å
93	K	56.7	Low	83.5	Confident	204 Å²	204	54.8 Å²	54.8	89%	0.887	27%	0.265	S	S	*	.	T	Hydrogen-bonded Turn	trans	-92.1	-9.5	-176.3	-66.1	-170.4	178.9	-174.3	0	114.1	D91	D91-K93 PolarHBondContact O-N 2.97Å; D91-K93 PolarHBondContact OD1-N 3.48Å
94	S	59.9	Low	83.7	Confident	31 Å²	31	54.5 Å²	54.5	22%	0.217	26%	0.262	C	S	.	.			trans	-109.1	43.8	-177	75.7	0	0	0	0	114	D91 T96 N99	D91-S94 PolarHBondContact O-N 3.13Å; D91-S94 WeakPolarHBondContact OD2-CB 3.47Å; D91-S94 PolarHBondContact OD2-OG 2.92Å; S94-T96 PolarHBondContact O-N 3.43Å; S94-N99 WeakPolarHBondContact CB-ND2 3.02Å; S94-N99 WeakPolarHBondContact O-CB 3.23Å; S94-N99 PolarHBondContact O-ND2 3.37Å; S94-N99 PolarHBondContact OG-ND2 2.92Å
95	G	66.6	Low	83.9	Confident	39 Å²	39	54.5 Å²	54.5	40%	0.402	26%	0.262	S	S	.	.			trans	-65.5	33.7	-178.3	0	0	0	0	0	116.5	P177	G95-P177 WeakPolarHBondContact O-CB 3.33Å; G95-P177 WeakPolarHBondContact O-CG 3.43Å
96	T	83.3	Confident	84	Confident	61 Å²	61	53 Å²	53	37%	0.374	25%	0.254	S	S	.	.			trans	-62	146.5	174.4	71	0	0	0	0	110.6	S94 A98 N99 V100	S94-T96 PolarHBondContact O-N 3.43Å; T96-A98 PolarHBondContact O-N 3.33Å; T96-A98 VanDerWaalsContact O-N 3.13Å; T96-N99 WeakPolarHBondContact O-CB 3.04Å; T96-N99 PolarHBondContact O-N 3.4Å; T96-N99 PolarHBondContact OG1-N 3.15Å; T96-V100 PolarHBondContact O-N 3.2Å
97	P	87.9	Confident	84.3	Confident	11 Å²	11	49.3 Å²	49.3	7%	0.071	25%	0.247	C	C	.	.	H	α-helix	trans	-49.5	-40	177	-31.1	36	0	0	0	113.9	N99 V100 F101 R175 A180	P97-N99 PolarHBondContact O-N 3.14Å; P97-V100 WeakPolarHBondContact O-CB 3.34Å; P97-V100 PolarHBondContact O-N 2.87Å; P97-F101 HydrophobicContact CB-CE2 4.29Å; P97-F101 WeakPolarHBondContact O-CD2 3.48Å; P97-F101 PolarHBondContact O-N 2.85Å; P97-R175 HydrophobicContact CG-CB 4Å; P97-R175 WeakPolarHBondContact CG-O 3.34Å; P97-A180 HydrophobicContact CB-CB 3.9Å
98	A	86.1	Confident	84.6	Confident	0 Å²	0	48.2 Å²	48.2	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-62.8	-39.5	176.3	0	0	0	0	0	113.2	T96 V100 F101 L102 V332	T96-A98 PolarHBondContact O-N 3.33Å; T96-A98 VanDerWaalsContact O-N 3.13Å; A98-V100 VanDerWaalsContact C-N 3.28Å; A98-V100 PolarHBondContact O-N 2.86Å; A98-F101 PolarHBondContact O-N 3.32Å; A98-L102 VanDerWaalsContact O-CG 3.26Å; A98-L102 WeakPolarHBondContact O-CG 3.32Å; A98-L102 PolarHBondContact O-N 2.95Å; A98-V332 HydrophobicContact CB-CG1 4.42Å
99	N	87.5	Confident	85.1	Confident	23 Å²	23	47.3 Å²	47.3	12%	0.123	24%	0.237	C	C	.	.	H	α-helix	trans	-66.5	-33.9	176.8	-71.6	-2.5	0	0	0	111.4	S94 T96 P97 L102 M103	S94-N99 WeakPolarHBondContact CB-ND2 3.02Å; S94-N99 WeakPolarHBondContact O-CB 3.23Å; S94-N99 PolarHBondContact O-ND2 3.37Å; S94-N99 PolarHBondContact OG-ND2 2.92Å; T96-N99 WeakPolarHBondContact O-CB 3.04Å; T96-N99 PolarHBondContact O-N 3.4Å; T96-N99 PolarHBondContact OG1-N 3.15Å; P97-N99 PolarHBondContact O-N 3.14Å; N99-L102 PolarHBondContact O-N 3.31Å; N99-M103 WeakPolarHBondContact O-CB 3.19Å; N99-M103 PolarHBondContact O-N 3.02Å
100	V	92.3	Very high	85.5	Confident	8 Å²	8	44.6 Å²	44.6	5%	0.048	22%	0.223	C	C	.	.	H	α-helix	trans	-62.1	-49.4	172.4	176.8	0	0	0	0	110.5	T96 P97 A98 L102 M103 H104 A180 H181	T96-V100 PolarHBondContact O-N 3.2Å; P97-V100 WeakPolarHBondContact O-CB 3.34Å; P97-V100 PolarHBondContact O-N 2.87Å; A98-V100 VanDerWaalsContact C-N 3.28Å; A98-V100 PolarHBondContact O-N 2.86Å; V100-L102 VanDerWaalsContact C-N 3.35Å; V100-L102 PolarHBondContact O-N 3.17Å; V100-M103 PolarHBondContact O-N 3.45Å; V100-H104 PolarHBondContact O-CD2 2.81Å; V100-H104 VanDerWaalsContact O-CD2 3.27Å; V100-H104 PolarHBondContact O-N 3.42Å; V100-H104 VanDerWaalsContact O-N 3.12Å; V100-A180 HydrophobicContact CB-CB 3.84Å; V100-A180 HydrophobicContact CG1-CB 3.86Å; V100-A180 HydrophobicContact CG2-CB 4.29Å; V100-H181 WeakPolarHBondContact CG1-ND1 3.25Å
101	F	93.4	Very high	86	Confident	15 Å²	15	37.1 Å²	37.1	7%	0.066	20%	0.198	C	C	.	.	H	α-helix	trans	-60.8	-41.6	177.2	-61.8	-50	0	0	0	112.5	P97 A98 M103 H104 L105 F153 C156 I157 D160 A180 A183 C184	P97-F101 HydrophobicContact CB-CE2 4.29Å; P97-F101 WeakPolarHBondContact O-CD2 3.48Å; P97-F101 PolarHBondContact O-N 2.85Å; A98-F101 PolarHBondContact O-N 3.32Å; F101-M103 VanDerWaalsContact C-N 3.35Å; F101-M103 PolarHBondContact O-N 3.09Å; F101-H104 PolarHBondContact O-N 2.93Å; F101-L105 WeakPolarHBondContact O-CB 3.49Å; F101-L105 PolarHBondContact O-N 3.49Å; F101-F153 HydrophobicContact CD1-CD1 4.21Å; F101-C156 HydrophobicContact CD1-CB 3.8Å; F101-C156 HydrophobicContact CD2-CB 4Å; F101-C156 HydrophobicContact CE1-CB 3.73Å; F101-C156 HydrophobicContact CE2-CB 3.92Å; F101-C156 HydrophobicContact CG-CB 3.97Å; F101-C156 HydrophobicContact CZ-CB 3.8Å; F101-I157 HydrophobicContact CB-CD1 4.12Å; F101-I157 HydrophobicContact CB-CG1 3.6Å; F101-I157 HydrophobicContact CD2-CG1 4.34Å; F101-I157 HydrophobicContact CG-CG1 4.34Å; F101-D160 HydrophobicContact CE2-CB 4.43Å; F101-A180 HydrophobicContact CE1-CB 4Å; F101-A180 HydrophobicContact CE2-CB 4.21Å; F101-A180 HydrophobicContact CZ-CB 3.76Å; F101-A183 HydrophobicContact CE1-CB 4.2Å; F101-C184 WeakPolarHBondContact CD1-SG 3.23Å
102	L	91.8	Very high	86.8	Confident	0 Å²	0	36.6 Å²	36.6	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-65.5	-35.8	176.7	-68	174	0	0	0	113	F88 A98 N99 V100 L105 A106 I157 M328 Y329 V332	F88-L102 HydrophobicContact CE2-CB 3.94Å; F88-L102 HydrophobicContact CZ-CB 3.82Å; F88-L102 HydrophobicContact CZ-CD1 4.1Å; A98-L102 VanDerWaalsContact O-CG 3.26Å; A98-L102 WeakPolarHBondContact O-CG 3.32Å; A98-L102 PolarHBondContact O-N 2.95Å; N99-L102 PolarHBondContact O-N 3.31Å; V100-L102 VanDerWaalsContact C-N 3.35Å; V100-L102 PolarHBondContact O-N 3.17Å; L102-L105 HydrophobicContact CD2-CD2 4.32Å; L102-L105 PolarHBondContact O-N 3.44Å; L102-A106 PolarHBondContact O-N 3.43Å; L102-I157 HydrophobicContact CD2-CD1 3.57Å; L102-I157 HydrophobicContact CG-CD1 4.21Å; L102-M328 HydrophobicContact CD2-CG 4.06Å; L102-M328 HydrophobicContact CD2-SD 3.67Å; L102-Y329 HydrophobicContact CB-CD1 4.24Å; L102-Y329 HydrophobicContact CB-CE1 4.09Å; L102-Y329 HydrophobicContact CD1-CD1 4.33Å; L102-Y329 HydrophobicContact CD2-CD1 3.82Å; L102-Y329 HydrophobicContact CD2-CE1 3.79Å; L102-Y329 HydrophobicContact CG-CD1 4.35Å; L102-Y329 HydrophobicContact CG-CE1 4.43Å; L102-V332 HydrophobicContact CD1-CB 3.7Å; L102-V332 HydrophobicContact CD1-CG1 3.49Å; L102-V332 VanDerWaalsContact CD1-CG1 3.49Å
103	M	92.6	Very high	88.3	Confident	48 Å²	48	28.7 Å²	28.7	24%	0.236	16%	0.16	C	C	.	.	H	α-helix	trans	-64	-44.2	175.4	-172.7	-177.2	74.6	0	0	110.9	L85 F88 N99 V100 F101 A106 V107	L85-M103 HydrophobicContact CD1-CG 3.58Å; F88-M103 HydrophobicContact CB-CB 4.38Å; F88-M103 HydrophobicContact CB-CG 4.27Å; F88-M103 HydrophobicContact CD2-CB 4.37Å; N99-M103 WeakPolarHBondContact O-CB 3.19Å; N99-M103 PolarHBondContact O-N 3.02Å; V100-M103 PolarHBondContact O-N 3.45Å; F101-M103 VanDerWaalsContact C-N 3.35Å; F101-M103 PolarHBondContact O-N 3.09Å; M103-A106 PolarHBondContact O-N 3.42Å; M103-V107 WeakPolarHBondContact O-CG2 3.41Å; M103-V107 PolarHBondContact O-N 2.87Å; M103-V107 VanDerWaalsContact O-N 3.07Å
104	H	95.4	Very high	90.1	Very high	33 Å²	33	24.8 Å²	24.8	15%	0.153	15%	0.148	C	C	.	.	H	α-helix	trans	-70.6	-31.9	176.7	-75.7	-79.2	0	0	0	113	V100 F101 V107 A108 F153 H181 C184 W188	V100-H104 PolarHBondContact O-CD2 2.81Å; V100-H104 VanDerWaalsContact O-CD2 3.27Å; V100-H104 PolarHBondContact O-N 3.42Å; V100-H104 VanDerWaalsContact O-N 3.12Å; F101-H104 PolarHBondContact O-N 2.93Å; H104-V107 PolarHBondContact O-N 3.34Å; H104-A108 PolarHBondContact O-N 2.88Å; H104-F153 HydrophobicContact CB-CD1 4.33Å; H104-F153 HydrophobicContact CB-CD2 4.32Å; H104-F153 HydrophobicContact CB-CE1 3.79Å; H104-F153 HydrophobicContact CB-CE2 3.76Å; H104-F153 HydrophobicContact CB-CZ 3.5Å; H104-F153 VanDerWaalsContact CB-CZ 3.5Å; H104-H181 AromaticContact NE2-ND1 3.99Å; H104-C184 VanDerWaalsContact CD2-CB 3.5Å; H104-C184 WeakPolarHBondContact CD2-CB 3.11Å; H104-C184 PolarHBondContact CD2-SG 3.29Å; H104-W188 AromaticContact CE1-NE1 3.85Å; H104-W188 AromaticContact CG-NE1 3.75Å; H104-W188 AromaticContact ND1-CD1 3.8Å; H104-W188 AromaticContact ND1-NE1 3.03Å; H104-W188 PolarHBondContact ND1-NE1 2.97Å
105	L	95	Very high	91.8	Very high	0 Å²	0	23.4 Å²	23.4	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-59.3	-50.7	169.9	-175.1	62.7	0	0	0	110.5	F101 L102 V107 A108 D109 S150 F153 L154 I157 D325 M328 Y329	F101-L105 WeakPolarHBondContact O-CB 3.49Å; F101-L105 PolarHBondContact O-N 3.49Å; L102-L105 HydrophobicContact CD2-CD2 4.32Å; L102-L105 PolarHBondContact O-N 3.44Å; L105-V107 VanDerWaalsContact C-N 3.28Å; L105-V107 PolarHBondContact O-N 3.43Å; L105-A108 WeakPolarHBondContact O-CA 3.36Å; L105-A108 WeakPolarHBondContact O-CB 3.36Å; L105-A108 PolarHBondContact O-N 3.49Å; L105-D109 PolarHBondContact O-N 2.91Å; L105-D109 VanDerWaalsContact O-OD2 3.14Å; L105-S150 WeakPolarHBondContact CD1-OG 3.18Å; L105-F153 HydrophobicContact CB-CB 4.34Å; L105-F153 HydrophobicContact CD1-CB 4.23Å; L105-L154 HydrophobicContact CD2-CD2 4.19Å; L105-I157 HydrophobicContact CD2-CD1 4.37Å; L105-D325 HydrophobicContact CD2-CB 4.38Å; L105-M328 HydrophobicContact CD2-SD 4.43Å; L105-Y329 HydrophobicContact CD2-CE1 4.4Å
106	A	95.4	Very high	93.2	Very high	0 Å²	0	21.7 Å²	21.7	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-58.7	-37	176	0	0	0	0	0	113	N81 L85 L102 M103 D109 L110 Y329	N81-A106 HydrophobicContact CB-CB 4.4Å; L85-A106 HydrophobicContact CB-CB 4.32Å; L102-A106 PolarHBondContact O-N 3.43Å; M103-A106 PolarHBondContact O-N 3.42Å; A106-D109 PolarHBondContact O-N 3.02Å; A106-L110 WeakPolarHBondContact O-CB 3.32Å; A106-L110 VanDerWaalsContact O-CG 3.24Å; A106-L110 WeakPolarHBondContact O-CG 3.27Å; A106-L110 PolarHBondContact O-N 3.43Å; A106-Y329 WeakPolarHBondContact CA-OH 3.22Å; A106-Y329 PolarHBondContact N-OH 3.45Å
107	V	96.4	Very high	93.7	Very high	59 Å²	59	21 Å²	21	36%	0.358	12%	0.117	S	C	.	.	H	α-helix	trans	-65	-42.6	173.6	170.9	0	0	0	0	111.3	L85 M103 H104 L105 L110 S111 W188	L85-V107 HydrophobicContact CD1-CG2 4Å; L85-V107 HydrophobicContact CD2-CG2 4.09Å; M103-V107 WeakPolarHBondContact O-CG2 3.41Å; M103-V107 PolarHBondContact O-N 2.87Å; M103-V107 VanDerWaalsContact O-N 3.07Å; H104-V107 PolarHBondContact O-N 3.34Å; L105-V107 VanDerWaalsContact C-N 3.28Å; L105-V107 PolarHBondContact O-N 3.43Å; V107-L110 PolarHBondContact O-N 3.3Å; V107-S111 PolarHBondContact O-N 3.4Å; V107-S111 VanDerWaalsContact O-N 3.07Å; V107-W188 HydrophobicContact CB-CZ2 4.49Å; V107-W188 HydrophobicContact CG1-CH2 4.41Å; V107-W188 HydrophobicContact CG1-CZ2 4.12Å
108	A	96.6	Very high	94.1	Very high	0 Å²	0	21.6 Å²	21.6	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-62	-43.2	175.5	0	0	0	0	0	111.4	H104 L105 S111 C112 N146 A149 W188	H104-A108 PolarHBondContact O-N 2.88Å; L105-A108 WeakPolarHBondContact O-CA 3.36Å; L105-A108 WeakPolarHBondContact O-CB 3.36Å; L105-A108 PolarHBondContact O-N 3.49Å; A108-S111 WeakPolarHBondContact O-CB 3.35Å; A108-S111 PolarHBondContact O-N 2.93Å; A108-S111 PolarHBondContact O-OG 3.47Å; A108-C112 PolarHBondContact O-N 3.31Å; A108-N146 PolarHBondContact O-ND2 3.07Å; A108-A149 HydrophobicContact CB-CB 3.89Å; A108-W188 HydrophobicContact CB-CH2 3.77Å; A108-W188 HydrophobicContact CB-CZ2 4.21Å
109	D	96.4	Very high	94.4	Very high	2 Å²	2	21.6 Å²	21.6	1%	0.011	12%	0.12	C	C	.	.	H	α-helix	trans	-66.8	-41.8	179	-61	-40.5	0	0	0	112.3	N81 L105 A106 S111 C112 V113 N146 S150 N321	N81-D109 HydrophobicContact CB-CB 4.39Å; N81-D109 PolarHBondContact OD1-OD2 2.91Å; L105-D109 PolarHBondContact O-N 2.91Å; L105-D109 VanDerWaalsContact O-OD2 3.14Å; A106-D109 PolarHBondContact O-N 3.02Å; D109-S111 PolarHBondContact O-N 2.93Å; D109-C112 CarbonylContact O-C 3.59Å; D109-C112 WeakPolarHBondContact O-CA 3.35Å; D109-C112 WeakPolarHBondContact O-CB 3.31Å; D109-C112 PolarHBondContact O-N 2.97Å; D109-V113 WeakPolarHBondContact O-CG2 3.43Å; D109-V113 PolarHBondContact O-N 3.19Å; D109-N146 VanDerWaalsContact CA-ND2 3.33Å; D109-N146 WeakPolarHBondContact CA-ND2 3.35Å; D109-N146 PolarHBondContact N-ND2 3.38Å; D109-N146 PolarHBondContact OD1-ND2 3.09Å; D109-S150 PolarHBondContact OD1-OG 3.3Å; D109-N321 PolarHBondContact OD1-ND2 2.92Å
110	L	96.4	Very high	94.8	Very high	36 Å²	36	21.9 Å²	21.9	19%	0.188	12%	0.121	C	C	.	.	H	α-helix	trans	-62.6	-29.4	174.1	-71.3	171.4	0	0	0	112.6	F78 N81 T82 L85 A106 V107 C112 V113	F78-L110 HydrophobicContact CD2-CD2 4.35Å; N81-L110 HydrophobicContact CB-CD2 3.92Å; N81-L110 HydrophobicContact CB-CG 3.86Å; T82-L110 WeakPolarHBondContact OG1-CD2 3.34Å; L85-L110 HydrophobicContact CB-CD1 4.35Å; L85-L110 HydrophobicContact CD2-CD1 3.55Å; A106-L110 WeakPolarHBondContact O-CB 3.32Å; A106-L110 VanDerWaalsContact O-CG 3.24Å; A106-L110 WeakPolarHBondContact O-CG 3.27Å; A106-L110 PolarHBondContact O-N 3.43Å; V107-L110 PolarHBondContact O-N 3.3Å; L110-C112 VanDerWaalsContact C-N 3.34Å; L110-V113 WeakPolarHBondContact O-CB 3.5Å; L110-V113 PolarHBondContact O-N 2.88Å
111	S	95.3	Very high	94.9	Very high	21 Å²	21	24 Å²	24	15%	0.147	13%	0.134	C	C	.	.	H	α-helix	trans	-67.5	-35.9	171.8	82.6	0	0	0	0	112.2	V107 A108 D109 L114	V107-S111 PolarHBondContact O-N 3.4Å; V107-S111 VanDerWaalsContact O-N 3.07Å; A108-S111 WeakPolarHBondContact O-CB 3.35Å; A108-S111 PolarHBondContact O-N 2.93Å; A108-S111 PolarHBondContact O-OG 3.47Å; D109-S111 PolarHBondContact O-N 2.93Å; S111-L114 PolarHBondContact O-N 2.89Å
112	C	94.6	Very high	94.9	Very high	5 Å²	5	23.6 Å²	23.6	3%	0.034	13%	0.132	C	C	.	.	H	α-helix	trans	-72.6	-31.2	175.2	-158.8	0	0	0	0	112.4	A108 D109 L110 L114 V115 L116 N146	A108-C112 PolarHBondContact O-N 3.31Å; D109-C112 CarbonylContact O-C 3.59Å; D109-C112 WeakPolarHBondContact O-CA 3.35Å; D109-C112 WeakPolarHBondContact O-CB 3.31Å; D109-C112 PolarHBondContact O-N 2.97Å; L110-C112 VanDerWaalsContact C-N 3.34Å; C112-L114 PolarHBondContact O-N 3Å; C112-L114 VanDerWaalsContact O-N 3.15Å; C112-V115 WeakPolarHBondContact O-CA 3.26Å; C112-V115 WeakPolarHBondContact O-CB 3.49Å; C112-V115 PolarHBondContact O-N 3.26Å; C112-L116 PolarHBondContact O-N 2.9Å; C112-N146 HydrophobicContact CB-CB 3.6Å; C112-N146 VanDerWaalsContact CB-CG 3.4Å; C112-N146 PolarHBondContact SG-OD1 3.42Å
113	V	95.8	Very high	94.8	Very high	6 Å²	6	23.7 Å²	23.7	4%	0.036	13%	0.132	C	C	.	.	H	α-helix	trans	-55.8	-31.5	175	168	0	0	0	0	111.9	F74 A77 F78 D109 L110 V115 L116 P117	F74-V113 HydrophobicContact CD2-CG1 3.65Å; F74-V113 HydrophobicContact CE2-CG1 3.53Å; A77-V113 HydrophobicContact CB-CG2 3.73Å; F78-V113 HydrophobicContact CB-CG1 3.89Å; F78-V113 HydrophobicContact CB-CG2 4.45Å; F78-V113 HydrophobicContact CD2-CG1 3.9Å; F78-V113 HydrophobicContact CG-CG1 4.31Å; D109-V113 WeakPolarHBondContact O-CG2 3.43Å; D109-V113 PolarHBondContact O-N 3.19Å; L110-V113 WeakPolarHBondContact O-CB 3.5Å; L110-V113 PolarHBondContact O-N 2.88Å; V113-V115 PolarHBondContact O-N 3.08Å; V113-L116 PolarHBondContact O-N 3.06Å; V113-P117 WeakPolarHBondContact O-CD 3.38Å
114	L	94.4	Very high	94.8	Very high	123 Å²	123	28.2 Å²	28.2	64%	0.644	15%	0.151	S	C	*	.	T	Hydrogen-bonded Turn	trans	-66.2	-25.4	174.3	-58.6	178.6	0	0	0	113	S111 C112 L142	S111-L114 PolarHBondContact O-N 2.89Å; C112-L114 PolarHBondContact O-N 3Å; C112-L114 VanDerWaalsContact O-N 3.15Å; L114-L142 HydrophobicContact CB-CD1 4.48Å
115	V	94.9	Very high	94.5	Very high	1 Å²	1	29.2 Å²	29.2	1%	0.006	16%	0.162	C	C	.	.	T	Hydrogen-bonded Turn	trans	-80.1	-37.7	-179.3	179.7	0	0	0	0	111.7	C112 V113 T118 R119 T139 L142	C112-V115 WeakPolarHBondContact O-CA 3.26Å; C112-V115 WeakPolarHBondContact O-CB 3.49Å; C112-V115 PolarHBondContact O-N 3.26Å; V113-V115 PolarHBondContact O-N 3.08Å; V115-T118 WeakPolarHBondContact O-CB 3.47Å; V115-T118 PolarHBondContact O-N 3.25Å; V115-T118 PolarHBondContact O-OG1 3.37Å; V115-R119 HydrophobicContact CG1-CG 4.18Å; V115-R119 PolarHBondContact O-N 3.31Å; V115-T139 HydrophobicContact CG1-CG2 3.64Å; V115-L142 HydrophobicContact CG2-CB 3.48Å; V115-L142 VanDerWaalsContact CG2-CB 3.48Å; V115-L142 HydrophobicContact CG2-CD1 4.17Å; V115-L142 HydrophobicContact CG2-CG 4.48Å
116	L	95.1	Very high	94.1	Very high	4 Å²	4	31.1 Å²	31.1	2%	0.021	18%	0.182	C	C	.	.	H	α-helix	trans	-57.6	-42.4	-171.5	-52.6	176.3	0	0	0	113.9	Y70 D73 F74 C112 V113 T118 R119 L120	Y70-L116 HydrophobicContact CD1-CD2 3.99Å; Y70-L116 HydrophobicContact CE1-CD2 4.38Å; D73-L116 HydrophobicContact CB-CD1 4.35Å; F74-L116 HydrophobicContact CB-CB 4.08Å; F74-L116 HydrophobicContact CB-CD1 4.16Å; F74-L116 HydrophobicContact CD2-CB 4.49Å; C112-L116 PolarHBondContact O-N 2.9Å; V113-L116 PolarHBondContact O-N 3.06Å; L116-T118 VanDerWaalsContact C-N 3.28Å; L116-T118 PolarHBondContact O-N 2.92Å; L116-R119 PolarHBondContact O-N 2.93Å; L116-L120 PolarHBondContact O-N 3.44Å
117	P	95.3	Very high	93.6	Very high	47 Å²	47	32 Å²	32	31%	0.305	19%	0.186	S	C	.	.	H	α-helix	trans	-62.4	-33.1	174.9	-24.3	34.6	0	0	0	113.4	F74 V113 R119 L120 V121	F74-P117 HydrophobicContact CD2-CG 3.76Å; F74-P117 HydrophobicContact CE2-CG 3.79Å; V113-P117 WeakPolarHBondContact O-CD 3.38Å; P117-R119 VanDerWaalsContact C-N 3.35Å; P117-L120 WeakPolarHBondContact O-CB 3.46Å; P117-L120 PolarHBondContact O-N 3.45Å; P117-V121 WeakPolarHBondContact O-CG2 3.25Å; P117-V121 PolarHBondContact O-N 3.42Å
118	T	94.6	Very high	93.3	Very high	23 Å²	23	32 Å²	32	14%	0.141	18%	0.182	C	C	.	.	H	α-helix	trans	-69.1	-37.2	177.7	72.8	0	0	0	0	111.3	V115 L116 Y122 W129 F131 T139	V115-T118 WeakPolarHBondContact O-CB 3.47Å; V115-T118 PolarHBondContact O-N 3.25Å; V115-T118 PolarHBondContact O-OG1 3.37Å; L116-T118 VanDerWaalsContact C-N 3.28Å; L116-T118 PolarHBondContact O-N 2.92Å; T118-Y122 WeakPolarHBondContact O-CB 3.1Å; T118-Y122 PolarHBondContact O-N 3.49Å; T118-Y122 VanDerWaalsContact O-N 3.07Å; T118-W129 HydrophobicContact CG2-CH2 4.32Å; T118-F131 HydrophobicContact CG2-CE2 4.4Å; T118-T139 PolarHBondContact OG1-OG1 3.37Å; T118-T139 VanDerWaalsContact OG1-OG1 3.09Å
119	R	93.8	Very high	93.1	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-66.2	-41.8	173	-63.3	-169.7	171	-104.1	6.5	111.4	Y70 V115 L116 P117 Y122 H123 L216 Y217	Y70-R119 HydrophobicContact CD1-CB 4.3Å; Y70-R119 HydrophobicContact CD2-CB 3.86Å; Y70-R119 HydrophobicContact CE1-CB 4.37Å; Y70-R119 HydrophobicContact CE2-CB 3.93Å; Y70-R119 HydrophobicContact CG-CB 4.06Å; V115-R119 HydrophobicContact CG1-CG 4.18Å; V115-R119 PolarHBondContact O-N 3.31Å; L116-R119 PolarHBondContact O-N 2.93Å; P117-R119 VanDerWaalsContact C-N 3.35Å; R119-Y122 WeakPolarHBondContact O-CB 3.26Å; R119-Y122 PolarHBondContact O-N 3.03Å; R119-H123 PolarHBondContact O-CD2 2.97Å; R119-H123 PolarHBondContact O-N 3.26Å; R119-H123 VanDerWaalsContact O-N 3.13Å; R119-L216 HydrophobicContact CG-CD2 3.67Å; R119-L216 PolarHBondContact NH1-O 3.07Å; R119-Y217 VanDerWaalsContact NH1-CE1 3.34Å; R119-Y217 VanDerWaalsContact NH1-CZ 3.33Å; R119-Y217 PolarHBondContact NH1-OH 3.29Å
120	L	94.8	Very high	93	Very high	28 Å²	28	35.2 Å²	35.2	15%	0.147	20%	0.203	C	C	.	.	H	α-helix	trans	-55.3	-53	175	177.3	65.1	0	0	0	111.6	A67 L71 L116 P117 Y122 H123 F124	A67-L120 HydrophobicContact CB-CD1 3.71Å; A67-L120 WeakPolarHBondContact O-CD1 3.28Å; L71-L120 HydrophobicContact CB-CD1 4.16Å; L71-L120 HydrophobicContact CB-CD2 4.37Å; L71-L120 HydrophobicContact CD1-CD2 4.2Å; L116-L120 PolarHBondContact O-N 3.44Å; P117-L120 WeakPolarHBondContact O-CB 3.46Å; P117-L120 PolarHBondContact O-N 3.45Å; L120-Y122 VanDerWaalsContact C-N 3.31Å; L120-Y122 PolarHBondContact O-N 3.32Å; L120-H123 PolarHBondContact O-N 2.91Å; L120-F124 HydrophobicContact CD1-CD2 3.76Å; L120-F124 HydrophobicContact CD1-CE2 3.51Å; L120-F124 HydrophobicContact CG-CD2 3.94Å; L120-F124 HydrophobicContact CG-CE2 4.01Å; L120-F124 WeakPolarHBondContact O-CD2 3.44Å; L120-F124 PolarHBondContact O-N 2.9Å
121	V	94.9	Very high	92.9	Very high	52 Å²	52	37.7 Å²	37.7	32%	0.315	21%	0.212	S	C	.	.	H	α-helix	trans	-63.9	-37.7	-179.7	171.7	0	0	0	0	111.5	P117 H123 F124 S125 P130 F131	P117-V121 WeakPolarHBondContact O-CG2 3.25Å; P117-V121 PolarHBondContact O-N 3.42Å; V121-H123 PolarHBondContact O-N 2.91Å; V121-F124 PolarHBondContact O-N 3.46Å; V121-S125 VanDerWaalsContact O-CB 3.27Å; V121-S125 WeakPolarHBondContact O-CB 3.44Å; V121-S125 PolarHBondContact O-N 2.89Å; V121-S125 PolarHBondContact O-OG 2.89Å; V121-P130 HydrophobicContact CG1-CG 3.96Å; V121-F131 HydrophobicContact CB-CE2 3.93Å; V121-F131 HydrophobicContact CB-CZ 3.71Å; V121-F131 HydrophobicContact CG1-CE2 3.87Å; V121-F131 HydrophobicContact CG1-CZ 3.63Å; V121-F131 HydrophobicContact CG2-CZ 4.01Å
122	Y	92.9	Very high	92.8	Very high	7 Å²	7	38.3 Å²	38.3	3%	0.027	22%	0.222	C	C	.	.	H	α-helix	trans	-58.6	-46.4	176.1	174.6	-94.6	0	0	0	112.4	T118 R119 L120 S125 N127 W129 L216 Y217	T118-Y122 WeakPolarHBondContact O-CB 3.1Å; T118-Y122 PolarHBondContact O-N 3.49Å; T118-Y122 VanDerWaalsContact O-N 3.07Å; R119-Y122 WeakPolarHBondContact O-CB 3.26Å; R119-Y122 PolarHBondContact O-N 3.03Å; L120-Y122 VanDerWaalsContact C-N 3.31Å; L120-Y122 PolarHBondContact O-N 3.32Å; Y122-S125 PolarHBondContact O-N 3.27Å; Y122-N127 HydrophobicContact CE1-CB 3.91Å; Y122-N127 WeakPolarHBondContact CE1-OD1 3.5Å; Y122-N127 VanDerWaalsContact CE2-C 3.44Å; Y122-N127 HydrophobicContact CE2-CB 4.13Å; Y122-N127 WeakPolarHBondContact CE2-O 3.42Å; Y122-N127 VanDerWaalsContact O-CA 3.29Å; Y122-N127 WeakPolarHBondContact O-CA 3.45Å; Y122-N127 PolarHBondContact O-N 3.12Å; Y122-N127 WeakPolarHBondContact OH-CB 3.42Å; Y122-W129 HydrophobicContact CD2-CB 4.23Å; Y122-W129 HydrophobicContact CD2-CE3 4.17Å; Y122-L216 HydrophobicContact CD1-CD1 3.77Å; Y122-L216 HydrophobicContact CD2-CD1 3.37Å; Y122-L216 HydrophobicContact CE1-CD1 3.96Å; Y122-L216 HydrophobicContact CE2-CD1 3.56Å; Y122-L216 HydrophobicContact CG-CD1 3.46Å; Y122-L216 VanDerWaalsContact CG-CD1 3.46Å; Y122-Y217 HydrophobicContact CD1-CE2 4.18Å; Y122-Y217 HydrophobicContact CE1-CD2 4.04Å; Y122-Y217 AromaticContact CE1-CE2 3.86Å; Y122-Y217 HydrophobicContact CE1-CE2 3.86Å
123	H	91.1	Very high	92.7	Very high	2 Å²	2	40 Å²	40	1%	0.009	23%	0.23	C	C	.	.	H	α-helix	trans	-67.7	-42	177.3	-75.5	-67.4	0	0	0	112.3	F66 A67 Y70 R119 L120 V121 S125 G126 Y217	F66-H123 AromaticContact CG-CE1 3.97Å; A67-H123 HydrophobicContact CB-CB 4.13Å; Y70-H123 AromaticContact CD2-CD2 3.87Å; Y70-H123 AromaticContact CE2-CD2 3.76Å; Y70-H123 AromaticContact CE2-NE2 3.66Å; R119-H123 PolarHBondContact O-CD2 2.97Å; R119-H123 PolarHBondContact O-N 3.26Å; R119-H123 VanDerWaalsContact O-N 3.13Å; L120-H123 PolarHBondContact O-N 2.91Å; V121-H123 PolarHBondContact O-N 2.91Å; H123-S125 VanDerWaalsContact C-N 3.27Å; H123-S125 PolarHBondContact O-N 3.24Å; H123-G126 PolarHBondContact O-N 3.2Å; H123-Y217 AromaticContact CE1-CE2 3.85Å; H123-Y217 AromaticContact NE2-CE2 3.61Å; H123-Y217 AromaticContact NE2-CZ 3.57Å; H123-Y217 PolarHBondContact NE2-OH 2.98Å
124	F	91.1	Very high	92.6	Very high	143 Å²	143	46 Å²	46	63%	0.627	26%	0.26	S	S	*	.	H	α-helix	trans	-63.2	-32.2	175.6	-90.2	-59.2	0	0	0	113.5	A67 L120 V121 G126	A67-F124 HydrophobicContact CB-CD2 4Å; A67-F124 HydrophobicContact CB-CE1 4.45Å; A67-F124 HydrophobicContact CB-CE2 3.83Å; A67-F124 HydrophobicContact CB-CG 4.4Å; A67-F124 HydrophobicContact CB-CZ 4.06Å; L120-F124 HydrophobicContact CD1-CD2 3.76Å; L120-F124 HydrophobicContact CD1-CE2 3.51Å; L120-F124 HydrophobicContact CG-CD2 3.94Å; L120-F124 HydrophobicContact CG-CE2 4.01Å; L120-F124 WeakPolarHBondContact O-CD2 3.44Å; L120-F124 PolarHBondContact O-N 2.9Å; V121-F124 PolarHBondContact O-N 3.46Å; F124-G126 PolarHBondContact O-N 3.45Å
125	S	90.1	Very high	92.6	Very high	55 Å²	55	41.4 Å²	41.4	39%	0.385	24%	0.24	S	C	.	.	T	Hydrogen-bonded Turn	trans	-85.2	17.8	-179.5	-50.2	0	0	0	0	112.7	V121 Y122 H123 N127 H128	V121-S125 VanDerWaalsContact O-CB 3.27Å; V121-S125 WeakPolarHBondContact O-CB 3.44Å; V121-S125 PolarHBondContact O-N 2.89Å; V121-S125 PolarHBondContact O-OG 2.89Å; Y122-S125 PolarHBondContact O-N 3.27Å; H123-S125 VanDerWaalsContact C-N 3.27Å; H123-S125 PolarHBondContact O-N 3.24Å; S125-N127 VanDerWaalsContact C-N 3.34Å; S125-N127 PolarHBondContact O-N 3.43Å; S125-H128 VanDerWaalsContact O-CB 3.27Å; S125-H128 WeakPolarHBondContact O-CB 3.5Å; S125-H128 PolarHBondContact O-N 3.45Å
126	G	85.6	Confident	92.6	Very high	40 Å²	40	41.3 Å²	41.3	41%	0.412	24%	0.239	S	C	.	.	T	Hydrogen-bonded Turn	trans	62.2	39.6	-179.5	0	0	0	0	0	113	H123 F124 H128	H123-G126 PolarHBondContact O-N 3.2Å; F124-G126 PolarHBondContact O-N 3.45Å; G126-H128 VanDerWaalsContact C-N 3.29Å; G126-H128 PolarHBondContact O-N 2.91Å
127	N	85.1	Confident	92.5	Very high	19 Å²	19	44.1 Å²	44.1	10%	0.102	25%	0.25	C	C	.	.	T	Hydrogen-bonded Turn	trans	70.3	17.9	-176.1	-54.9	-70.8	0	0	0	115.3	E58 Y122 S125	E58-N127 PolarHBondContact OE2-ND2 3.22Å; E58-N127 PolarHBondContact OE2-OD1 2.93Å; E58-N127 VanDerWaalsContact OE2-OD1 3.12Å; Y122-N127 HydrophobicContact CE1-CB 3.91Å; Y122-N127 WeakPolarHBondContact CE1-OD1 3.5Å; Y122-N127 VanDerWaalsContact CE2-C 3.44Å; Y122-N127 HydrophobicContact CE2-CB 4.13Å; Y122-N127 WeakPolarHBondContact CE2-O 3.42Å; Y122-N127 VanDerWaalsContact O-CA 3.29Å; Y122-N127 WeakPolarHBondContact O-CA 3.45Å; Y122-N127 PolarHBondContact O-N 3.12Å; Y122-N127 WeakPolarHBondContact OH-CB 3.42Å; S125-N127 VanDerWaalsContact C-N 3.34Å; S125-N127 PolarHBondContact O-N 3.43Å
128	H	89.9	Confident	92.5	Very high	59 Å²	59	45.8 Å²	45.8	27%	0.273	26%	0.255	S	S	.	.			trans	-82.4	134.6	168.2	-177.8	83.4	0	0	0	110.8	S125 G126 P130 T210 V211	S125-H128 VanDerWaalsContact O-CB 3.27Å; S125-H128 WeakPolarHBondContact O-CB 3.5Å; S125-H128 PolarHBondContact O-N 3.45Å; G126-H128 VanDerWaalsContact C-N 3.29Å; G126-H128 PolarHBondContact O-N 2.91Å; H128-P130 VanDerWaalsContact O-CD 3.28Å; H128-P130 WeakPolarHBondContact O-CD 3.05Å; H128-T210 HydrophobicContact CB-CG2 4.29Å; H128-V211 PolarHBondContact ND1-N 3.39Å
129	W	93.4	Very high	92.4	Very high	2 Å²	2	45 Å²	45	1%	0.008	25%	0.251	C	S	.	.			trans	-101.6	102.1	175.9	179.9	-97	0	0	0	111.5	T118 Y122 F131 G132 A135 C136 T139 V211 C213 L216	T118-W129 HydrophobicContact CG2-CH2 4.32Å; Y122-W129 HydrophobicContact CD2-CB 4.23Å; Y122-W129 HydrophobicContact CD2-CE3 4.17Å; W129-F131 HydrophobicContact CD2-CD2 4.04Å; W129-F131 AromaticContact CE2-CD2 3.91Å; W129-F131 AromaticContact CE3-CD2 3.95Å; W129-F131 HydrophobicContact CE3-CD2 3.95Å; W129-F131 HydrophobicContact CH2-CB 4.44Å; W129-F131 AromaticContact CH2-CD2 3.68Å; W129-F131 HydrophobicContact CH2-CD2 3.68Å; W129-F131 HydrophobicContact CH2-CE2 4.43Å; W129-F131 HydrophobicContact CH2-CG 4.44Å; W129-F131 HydrophobicContact CZ2-CB 3.69Å; W129-F131 AromaticContact CZ2-CD2 3.73Å; W129-F131 HydrophobicContact CZ2-CD2 3.73Å; W129-F131 HydrophobicContact CZ2-CG 4.14Å; W129-F131 AromaticContact CZ3-CD2 3.79Å; W129-F131 HydrophobicContact CZ3-CD2 3.79Å; W129-F131 HydrophobicContact CZ3-CE2 4.26Å; W129-G132 PolarHBondContact NE1-O 2.71Å; W129-A135 HydrophobicContact CZ2-CB 3.79Å; W129-C136 HydrophobicContact CZ2-CB 4.01Å; W129-C136 VanDerWaalsContact CZ2-N 3.34Å; W129-T139 HydrophobicContact CH2-CG2 4.29Å; W129-V211 HydrophobicContact CB-CB 4.48Å; W129-V211 HydrophobicContact CB-CG1 4.23Å; W129-V211 WeakPolarHBondContact CB-O 3.48Å; W129-V211 PolarHBondContact N-O 3.24Å; W129-C213 HydrophobicContact CB-CB 4.19Å; W129-C213 HydrophobicContact CD2-CB 3.73Å; W129-C213 HydrophobicContact CE3-CB 4Å; W129-C213 HydrophobicContact CG-CB 3.8Å; W129-L216 HydrophobicContact CE3-CD1 3.81Å; W129-L216 HydrophobicContact CZ3-CD1 4.04Å
130	P	94.2	Very high	92.3	Very high	67 Å²	67	45 Å²	45	44%	0.435	25%	0.251	S	S	.	.			trans	-88.2	-10.7	-174	34.4	-36.9	0	0	0	114.4	V121 H128 G132	V121-P130 HydrophobicContact CG1-CG 3.96Å; H128-P130 VanDerWaalsContact O-CD 3.28Å; H128-P130 WeakPolarHBondContact O-CD 3.05Å; P130-G132 VanDerWaalsContact C-N 3.32Å; P130-G132 PolarHBondContact O-N 3.13Å
131	F	93.8	Very high	92.3	Very high	88 Å²	88	45 Å²	45	39%	0.386	25%	0.25	S	C	.	.	S	Bend	trans	-86.1	0.6	-167.8	-53.1	-76.3	0	0	0	114.7	T118 V121 W129 A135	T118-F131 HydrophobicContact CG2-CE2 4.4Å; V121-F131 HydrophobicContact CB-CE2 3.93Å; V121-F131 HydrophobicContact CB-CZ 3.71Å; V121-F131 HydrophobicContact CG1-CE2 3.87Å; V121-F131 HydrophobicContact CG1-CZ 3.63Å; V121-F131 HydrophobicContact CG2-CZ 4.01Å; W129-F131 HydrophobicContact CD2-CD2 4.04Å; W129-F131 AromaticContact CE2-CD2 3.91Å; W129-F131 AromaticContact CE3-CD2 3.95Å; W129-F131 HydrophobicContact CE3-CD2 3.95Å; W129-F131 HydrophobicContact CH2-CB 4.44Å; W129-F131 AromaticContact CH2-CD2 3.68Å; W129-F131 HydrophobicContact CH2-CD2 3.68Å; W129-F131 HydrophobicContact CH2-CE2 4.43Å; W129-F131 HydrophobicContact CH2-CG 4.44Å; W129-F131 HydrophobicContact CZ2-CB 3.69Å; W129-F131 AromaticContact CZ2-CD2 3.73Å; W129-F131 HydrophobicContact CZ2-CD2 3.73Å; W129-F131 HydrophobicContact CZ2-CG 4.14Å; W129-F131 AromaticContact CZ3-CD2 3.79Å; W129-F131 HydrophobicContact CZ3-CD2 3.79Å; W129-F131 HydrophobicContact CZ3-CE2 4.26Å; F131-A135 HydrophobicContact CB-CB 3.51Å; F131-A135 WeakPolarHBondContact O-CB 3.48Å
132	G	93.4	Very high	92.3	Very high	34 Å²	34	44.3 Å²	44.3	35%	0.351	24%	0.244	S	C	.	.	H	α-helix	trans	74.3	178.6	-178.9	0	0	0	0	0	114.6	W129 P130 C136	W129-G132 PolarHBondContact NE1-O 2.71Å; P130-G132 VanDerWaalsContact C-N 3.32Å; P130-G132 PolarHBondContact O-N 3.13Å; G132-C136 PolarHBondContact O-N 2.73Å
133	E	92.5	Very high	92.3	Very high	41 Å²	41	44 Å²	44	19%	0.192	24%	0.243	C	C	.	.	H	α-helix	trans	-64.2	-45.4	-169.3	175.1	62.7	-174.4	0	0	113.7	A135 C136 R137 Q202 Q203 T204	E133-A135 VanDerWaalsContact C-N 3.35Å; E133-A135 PolarHBondContact O-N 2.88Å; E133-C136 WeakPolarHBondContact O-CB 3Å; E133-C136 PolarHBondContact O-N 3.32Å; E133-C136 VanDerWaalsContact O-N 3.13Å; E133-R137 WeakPolarHBondContact O-CG 3.02Å; E133-R137 PolarHBondContact O-N 2.86Å; E133-R137 VanDerWaalsContact O-N 3.1Å; E133-R137 IonicContact OE1-CZ 2.93Å; E133-R137 VanDerWaalsContact OE1-CZ 3.25Å; E133-R137 IonicContact OE1-NE 2.61Å; E133-R137 PolarHBondContact OE1-NE 3.44Å; E133-R137 IonicContact OE1-NH2 3.29Å; E133-R137 PolarHBondContact OE1-NH2 3.43Å; E133-Q202 WeakPolarHBondContact OE1-CA 3.36Å; E133-Q203 PolarHBondContact OE1-N 3.39Å; E133-T204 WeakPolarHBondContact OE2-CA 3.07Å; E133-T204 WeakPolarHBondContact OE2-CB 3.44Å; E133-T204 WeakPolarHBondContact OE2-CG2 3.41Å; E133-T204 PolarHBondContact OE2-N 3.08Å; E133-T204 PolarHBondContact OE2-OG1 3.3Å
134	I	94.4	Very high	92.4	Very high	130 Å²	130	44.5 Å²	44.5	67%	0.667	25%	0.245	S	C	*	.	H	α-helix	trans	-61.2	-45.7	-175.7	-62.8	172.7	0	0	0	110.6	C136 R137 L138	I134-C136 VanDerWaalsContact C-N 3.31Å; I134-C136 PolarHBondContact O-N 2.95Å; I134-R137 PolarHBondContact O-N 3.31Å; I134-L138 HydrophobicContact CG2-CD1 4.02Å; I134-L138 HydrophobicContact CG2-CG 4.5Å; I134-L138 WeakPolarHBondContact O-CG 3.26Å; I134-L138 PolarHBondContact O-N 2.92Å
135	A	94.3	Very high	92.5	Very high	27 Å²	27	38.3 Å²	38.3	22%	0.223	22%	0.218	C	C	.	.	H	α-helix	trans	-63.2	-38	177.7	0	0	0	0	0	111.7	W129 F131 E133 R137 L138 T139	W129-A135 HydrophobicContact CZ2-CB 3.79Å; F131-A135 HydrophobicContact CB-CB 3.51Å; F131-A135 WeakPolarHBondContact O-CB 3.48Å; E133-A135 VanDerWaalsContact C-N 3.35Å; E133-A135 PolarHBondContact O-N 2.88Å; A135-R137 VanDerWaalsContact C-N 3.34Å; A135-R137 PolarHBondContact O-N 3.47Å; A135-L138 PolarHBondContact O-N 3Å; A135-T139 VanDerWaalsContact O-CB 3.29Å; A135-T139 WeakPolarHBondContact O-CB 3.46Å; A135-T139 PolarHBondContact O-N 2.89Å; A135-T139 PolarHBondContact O-OG1 3.1Å
136	C	93.7	Very high	92.8	Very high	0 Å²	0	35.8 Å²	35.8	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-61.3	-43.8	177.4	173.3	0	0	0	0	111.4	W129 G132 E133 I134 G140 Q203 T204 C213	W129-C136 HydrophobicContact CZ2-CB 4.01Å; W129-C136 VanDerWaalsContact CZ2-N 3.34Å; G132-C136 PolarHBondContact O-N 2.73Å; E133-C136 WeakPolarHBondContact O-CB 3Å; E133-C136 PolarHBondContact O-N 3.32Å; E133-C136 VanDerWaalsContact O-N 3.13Å; I134-C136 VanDerWaalsContact C-N 3.31Å; I134-C136 PolarHBondContact O-N 2.95Å; C136-G140 PolarHBondContact O-N 3.06Å; C136-G140 VanDerWaalsContact O-N 3.16Å; C136-Q203 WeakPolarHBondContact SG-CB 3.28Å; C136-T204 HydrophobicContact CB-CG2 3.79Å; C136-C213 VanDerWaalsContact CA-SG 3.5Å; C136-C213 HydrophobicContact CB-CB 3.84Å; C136-C213 WeakPolarHBondContact CB-SG 3.5Å; C136-C213 WeakPolarHBondContact SG-CA 3.4Å; C136-C213 WeakPolarHBondContact SG-CB 3.25Å; C136-C213 CovalentContact SG-SG 2.03Å; C136-C213 PolarHBondContact SG-SG 3.29Å
137	R	93.6	Very high	93.2	Very high	63 Å²	63	33.9 Å²	33.9	24%	0.238	18%	0.18	C	C	.	.	H	α-helix	trans	-63.9	-45.9	176.3	-63.2	-173.1	-165	178.1	-2.4	112.3	E133 I134 A135 G140 F141 L199 V200 S201 Q203	E133-R137 WeakPolarHBondContact O-CG 3.02Å; E133-R137 PolarHBondContact O-N 2.86Å; E133-R137 VanDerWaalsContact O-N 3.1Å; E133-R137 IonicContact OE1-CZ 2.93Å; E133-R137 VanDerWaalsContact OE1-CZ 3.25Å; E133-R137 IonicContact OE1-NE 2.61Å; E133-R137 PolarHBondContact OE1-NE 3.44Å; E133-R137 IonicContact OE1-NH2 3.29Å; E133-R137 PolarHBondContact OE1-NH2 3.43Å; I134-R137 PolarHBondContact O-N 3.31Å; A135-R137 VanDerWaalsContact C-N 3.34Å; A135-R137 PolarHBondContact O-N 3.47Å; R137-G140 PolarHBondContact O-N 3.42Å; R137-F141 WeakPolarHBondContact O-CB 3.34Å; R137-F141 PolarHBondContact O-N 3.03Å; R137-L199 WeakPolarHBondContact CD-O 3.31Å; R137-L199 PolarHBondContact NH1-O 3.43Å; R137-V200 PolarHBondContact NH1-O 3.22Å; R137-S201 WeakPolarHBondContact CD-O 3.14Å; R137-S201 PolarHBondContact NE-O 3.19Å; R137-Q203 HydrophobicContact CG-CB 4.29Å; R137-Q203 HydrophobicContact CG-CG 4.05Å
138	L	94.7	Very high	93.7	Very high	81 Å²	81	33.5 Å²	33.5	42%	0.424	18%	0.178	S	C	.	.	H	α-helix	trans	-62.9	-44.5	178	-74.3	173	0	0	0	111.9	I134 A135 G140 F141 L142 L199	I134-L138 HydrophobicContact CG2-CD1 4.02Å; I134-L138 HydrophobicContact CG2-CG 4.5Å; I134-L138 WeakPolarHBondContact O-CG 3.26Å; I134-L138 PolarHBondContact O-N 2.92Å; A135-L138 PolarHBondContact O-N 3Å; L138-G140 VanDerWaalsContact C-N 3.25Å; L138-G140 PolarHBondContact O-N 3.27Å; L138-F141 PolarHBondContact O-N 3.48Å; L138-L142 WeakPolarHBondContact O-CB 3.14Å; L138-L142 WeakPolarHBondContact O-CG 2.99Å; L138-L142 PolarHBondContact O-N 2.99Å; L138-L199 HydrophobicContact CD2-CD2 3.88Å
139	T	93.7	Very high	94	Very high	8 Å²	8	30.8 Å²	30.8	5%	0.049	17%	0.166	C	C	.	.	H	α-helix	trans	-55	-44.6	176	-83.2	0	0	0	0	111.2	V115 T118 W129 A135 F143 L216	V115-T139 HydrophobicContact CG1-CG2 3.64Å; T118-T139 PolarHBondContact OG1-OG1 3.37Å; T118-T139 VanDerWaalsContact OG1-OG1 3.09Å; W129-T139 HydrophobicContact CH2-CG2 4.29Å; A135-T139 VanDerWaalsContact O-CB 3.29Å; A135-T139 WeakPolarHBondContact O-CB 3.46Å; A135-T139 PolarHBondContact O-N 2.89Å; A135-T139 PolarHBondContact O-OG1 3.1Å; T139-F143 VanDerWaalsContact O-CB 3.3Å; T139-F143 WeakPolarHBondContact O-CB 3.23Å; T139-F143 PolarHBondContact O-N 2.9Å; T139-F143 VanDerWaalsContact O-N 3.08Å; T139-L216 HydrophobicContact CG2-CD2 4.05Å
140	G	91.6	Very high	94.1	Very high	0 Å²	0	30.7 Å²	30.7	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-62.6	-54	173.8	0	0	0	0	0	114.8	C136 R137 L138 L142 F143 Y144	C136-G140 PolarHBondContact O-N 3.06Å; C136-G140 VanDerWaalsContact O-N 3.16Å; R137-G140 PolarHBondContact O-N 3.42Å; L138-G140 VanDerWaalsContact C-N 3.25Å; L138-G140 PolarHBondContact O-N 3.27Å; G140-L142 VanDerWaalsContact C-N 3.31Å; G140-L142 PolarHBondContact O-N 2.73Å; G140-F143 PolarHBondContact O-N 3.3Å; G140-Y144 WeakPolarHBondContact O-CD2 3.23Å; G140-Y144 PolarHBondContact O-N 3.33Å; G140-Y144 VanDerWaalsContact O-N 3.07Å
141	F	93.6	Very high	94.1	Very high	28 Å²	28	27.5 Å²	27.5	12%	0.123	15%	0.145	C	C	.	.	H	α-helix	trans	-53.5	-50.1	179.9	172	-98.5	0	0	0	111.1	R137 L138 Y144 L145 A192 M195 L199	R137-F141 WeakPolarHBondContact O-CB 3.34Å; R137-F141 PolarHBondContact O-N 3.03Å; L138-F141 PolarHBondContact O-N 3.48Å; F141-Y144 PolarHBondContact O-N 3.45Å; F141-L145 HydrophobicContact CE1-CD1 4.47Å; F141-L145 HydrophobicContact CE1-CD2 3.89Å; F141-L145 HydrophobicContact CZ-CD1 4.01Å; F141-L145 HydrophobicContact CZ-CD2 4.24Å; F141-L145 WeakPolarHBondContact O-CB 3.45Å; F141-L145 PolarHBondContact O-N 3.24Å; F141-A192 HydrophobicContact CZ-CB 4.42Å; F141-M195 HydrophobicContact CD2-CB 3.72Å; F141-M195 HydrophobicContact CE2-CB 3.79Å; F141-L199 HydrophobicContact CB-CD2 3.55Å; F141-L199 HydrophobicContact CB-CG 3.99Å; F141-L199 HydrophobicContact CD1-CD1 4.46Å; F141-L199 HydrophobicContact CD1-CD2 4.32Å; F141-L199 HydrophobicContact CD2-CD1 3.82Å; F141-L199 HydrophobicContact CD2-CD2 4.26Å; F141-L199 HydrophobicContact CD2-CG 3.85Å; F141-L199 HydrophobicContact CE2-CD1 4.03Å; F141-L199 HydrophobicContact CG-CD1 4.05Å; F141-L199 HydrophobicContact CG-CD2 3.79Å; F141-L199 HydrophobicContact CG-CG 3.92Å; F141-L199 HydrophobicContact CZ-CD1 4.44Å
142	L	95.6	Very high	94.2	Very high	36 Å²	36	25.2 Å²	25.2	19%	0.188	13%	0.134	C	C	.	.	H	α-helix	trans	-66.4	-39.3	-178.7	-69.4	176.9	0	0	0	112.9	L114 V115 L138 G140 Y144 L145 N146	L114-L142 HydrophobicContact CB-CD1 4.48Å; V115-L142 HydrophobicContact CG2-CB 3.48Å; V115-L142 VanDerWaalsContact CG2-CB 3.48Å; V115-L142 HydrophobicContact CG2-CD1 4.17Å; V115-L142 HydrophobicContact CG2-CG 4.48Å; L138-L142 WeakPolarHBondContact O-CB 3.14Å; L138-L142 WeakPolarHBondContact O-CG 2.99Å; L138-L142 PolarHBondContact O-N 2.99Å; G140-L142 VanDerWaalsContact C-N 3.31Å; G140-L142 PolarHBondContact O-N 2.73Å; L142-Y144 PolarHBondContact O-N 2.9Å; L142-L145 HydrophobicContact CD2-CD2 4.2Å; L142-N146 WeakPolarHBondContact O-CB 3.44Å; L142-N146 PolarHBondContact O-N 2.87Å
143	F	93.9	Very high	94.3	Very high	1 Å²	1	23.6 Å²	23.6	0%	0.004	12%	0.117	C	C	.	.	H	α-helix	trans	-60.3	-47.4	176.6	177.9	-103	0	0	0	111.5	T139 G140 M147 Y283 T318	T139-F143 VanDerWaalsContact O-CB 3.3Å; T139-F143 WeakPolarHBondContact O-CB 3.23Å; T139-F143 PolarHBondContact O-N 2.9Å; T139-F143 VanDerWaalsContact O-N 3.08Å; G140-F143 PolarHBondContact O-N 3.3Å; F143-M147 PolarHBondContact O-N 3.25Å; F143-Y283 HydrophobicContact CE1-CE2 4.5Å; F143-T318 HydrophobicContact CE2-CG2 4.39Å; F143-T318 HydrophobicContact CZ-CG2 3.97Å
144	Y	92.1	Very high	94.3	Very high	13 Å²	13	21.7 Å²	21.7	5%	0.051	11%	0.108	C	C	.	.	H	α-helix	trans	-73.2	-38.9	179.2	-85.8	-74.5	0	0	0	113.5	G140 F141 L142 N146 M147 Y148 M195 L198 E219 Y283	G140-Y144 WeakPolarHBondContact O-CD2 3.23Å; G140-Y144 PolarHBondContact O-N 3.33Å; G140-Y144 VanDerWaalsContact O-N 3.07Å; F141-Y144 PolarHBondContact O-N 3.45Å; L142-Y144 PolarHBondContact O-N 2.9Å; Y144-N146 VanDerWaalsContact C-N 3.3Å; Y144-N146 PolarHBondContact O-N 2.97Å; Y144-M147 HydrophobicContact CD1-CE 3.57Å; Y144-M147 HydrophobicContact CE1-CE 3.7Å; Y144-M147 PolarHBondContact O-N 2.94Å; Y144-Y148 HydrophobicContact CD1-CD2 4.29Å; Y144-Y148 AromaticContact CD1-CE2 3.71Å; Y144-Y148 HydrophobicContact CD1-CE2 3.71Å; Y144-Y148 HydrophobicContact CE1-CE2 4.38Å; Y144-Y148 WeakPolarHBondContact O-CD2 3.27Å; Y144-Y148 PolarHBondContact O-N 2.96Å; Y144-M195 HydrophobicContact CD1-SD 4.45Å; Y144-M195 HydrophobicContact CG-SD 4.35Å; Y144-L198 HydrophobicContact CD2-CD1 3.68Å; Y144-L198 HydrophobicContact CE2-CD1 4.43Å; Y144-L198 HydrophobicContact CG-CD1 4.06Å; Y144-E219 WeakPolarHBondContact CE2-OE1 3.42Å; Y144-E219 VanDerWaalsContact CZ-OE1 3.23Å; Y144-E219 PolarHBondContact OH-OE1 2.87Å; Y144-E219 PolarHBondContact OH-OE2 2.91Å; Y144-Y283 HydrophobicContact CE1-CE1 4.28Å; Y144-Y283 PolarHBondContact OH-OH 3.44Å
145	L	94.3	Very high	94.3	Very high	13 Å²	13	16 Å²	16	7%	0.068	8%	0.079	C	C	.	.	H	α-helix	trans	-55.5	-48.7	172.9	-176.3	81.4	0	0	0	109.7	F141 L142 A149 W188 V191 A192	F141-L145 HydrophobicContact CE1-CD1 4.47Å; F141-L145 HydrophobicContact CE1-CD2 3.89Å; F141-L145 HydrophobicContact CZ-CD1 4.01Å; F141-L145 HydrophobicContact CZ-CD2 4.24Å; F141-L145 WeakPolarHBondContact O-CB 3.45Å; F141-L145 PolarHBondContact O-N 3.24Å; L142-L145 HydrophobicContact CD2-CD2 4.2Å; L145-A149 WeakPolarHBondContact O-CB 3.2Å; L145-A149 PolarHBondContact O-N 2.89Å; L145-W188 HydrophobicContact CD1-CE3 4.42Å; L145-W188 HydrophobicContact CD1-CZ3 4.24Å; L145-W188 HydrophobicContact CD2-CZ3 3.93Å; L145-W188 HydrophobicContact CG-CZ3 4Å; L145-V191 HydrophobicContact CD1-CB 4.5Å; L145-V191 HydrophobicContact CD1-CG1 3.99Å; L145-A192 HydrophobicContact CD1-CB 4.08Å
146	N	95.6	Very high	94.3	Very high	1 Å²	1	16.1 Å²	16.1	1%	0.005	8%	0.078	C	C	.	.	H	α-helix	trans	-60.2	-55.2	175.1	170	-106.1	0	0	0	111.9	A108 D109 C112 L142 Y144 Y148 A149 S150	A108-N146 PolarHBondContact O-ND2 3.07Å; D109-N146 VanDerWaalsContact CA-ND2 3.33Å; D109-N146 WeakPolarHBondContact CA-ND2 3.35Å; D109-N146 PolarHBondContact N-ND2 3.38Å; D109-N146 PolarHBondContact OD1-ND2 3.09Å; C112-N146 HydrophobicContact CB-CB 3.6Å; C112-N146 VanDerWaalsContact CB-CG 3.4Å; C112-N146 PolarHBondContact SG-OD1 3.42Å; L142-N146 WeakPolarHBondContact O-CB 3.44Å; L142-N146 PolarHBondContact O-N 2.87Å; Y144-N146 VanDerWaalsContact C-N 3.3Å; Y144-N146 PolarHBondContact O-N 2.97Å; N146-Y148 VanDerWaalsContact C-N 3.32Å; N146-Y148 PolarHBondContact O-N 3.49Å; N146-A149 PolarHBondContact O-N 3.42Å; N146-S150 PolarHBondContact ND2-OG 3.46Å; N146-S150 WeakPolarHBondContact O-CB 3.08Å; N146-S150 PolarHBondContact O-N 2.86Å; N146-S150 PolarHBondContact O-OG 3.11Å; N146-S150 VanDerWaalsContact O-OG 3.08Å
147	M	94.4	Very high	94.2	Very high	0 Å²	0	16.1 Å²	16.1	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-51	-51.6	-177.3	-179.2	-178.8	74.2	0	0	111.9	F143 Y144 I151 F280 Y283 T318	F143-M147 PolarHBondContact O-N 3.25Å; Y144-M147 HydrophobicContact CD1-CE 3.57Å; Y144-M147 HydrophobicContact CE1-CE 3.7Å; Y144-M147 PolarHBondContact O-N 2.94Å; M147-I151 HydrophobicContact CG-CD1 4.02Å; M147-I151 WeakPolarHBondContact O-CD1 3.47Å; M147-I151 VanDerWaalsContact O-CG1 3.25Å; M147-I151 WeakPolarHBondContact O-CG1 3.41Å; M147-I151 PolarHBondContact O-N 3.07Å; M147-F280 HydrophobicContact CG-CD1 3.94Å; M147-F280 HydrophobicContact CG-CE1 4Å; M147-Y283 HydrophobicContact CE-CD1 4.36Å; M147-Y283 HydrophobicContact CE-CE1 4.11Å; M147-Y283 HydrophobicContact SD-CD1 3.66Å; M147-Y283 HydrophobicContact SD-CE1 3.83Å; M147-Y283 HydrophobicContact SD-CG 4.46Å; M147-T318 HydrophobicContact CB-CG2 4.02Å; M147-T318 HydrophobicContact CG-CG2 3.66Å; M147-T318 HydrophobicContact SD-CG2 3.76Å
148	Y	94.8	Very high	94.1	Very high	11 Å²	11	13.1 Å²	13.1	4%	0.043	7%	0.067	C	C	.	.	H	α-helix	trans	-75.2	-40.5	-178.1	-70.6	-64.1	0	0	0	113	Y144 N146 S150 I151 Y152 M195 L229 A232	Y144-Y148 HydrophobicContact CD1-CD2 4.29Å; Y144-Y148 AromaticContact CD1-CE2 3.71Å; Y144-Y148 HydrophobicContact CD1-CE2 3.71Å; Y144-Y148 HydrophobicContact CE1-CE2 4.38Å; Y144-Y148 WeakPolarHBondContact O-CD2 3.27Å; Y144-Y148 PolarHBondContact O-N 2.96Å; N146-Y148 VanDerWaalsContact C-N 3.32Å; N146-Y148 PolarHBondContact O-N 3.49Å; Y148-S150 VanDerWaalsContact C-N 3.28Å; Y148-S150 PolarHBondContact O-N 2.69Å; Y148-I151 HydrophobicContact CD1-CD1 4.3Å; Y148-I151 PolarHBondContact O-N 3.32Å; Y148-Y152 WeakPolarHBondContact O-CD2 3.32Å; Y148-Y152 PolarHBondContact O-N 3.01Å; Y148-M195 HydrophobicContact CD2-CE 3.23Å; Y148-M195 HydrophobicContact CD2-SD 3.63Å; Y148-M195 HydrophobicContact CE2-CE 3.35Å; Y148-M195 HydrophobicContact CE2-SD 3.64Å; Y148-M195 HydrophobicContact CG-CE 4.1Å; Y148-L229 WeakPolarHBondContact OH-CD1 3.32Å; Y148-A232 HydrophobicContact CD1-CB 4.06Å; Y148-A232 HydrophobicContact CE1-CB 3.49Å; Y148-A232 VanDerWaalsContact CE1-CB 3.49Å
149	A	96.1	Very high	94	Very high	3 Å²	3	10.8 Å²	10.8	3%	0.025	6%	0.059	C	C	.	.	H	α-helix	trans	-57.2	-45.4	174.7	0	0	0	0	0	110.7	A108 L145 N146 Y152 F153 W188	A108-A149 HydrophobicContact CB-CB 3.89Å; L145-A149 WeakPolarHBondContact O-CB 3.2Å; L145-A149 PolarHBondContact O-N 2.89Å; N146-A149 PolarHBondContact O-N 3.42Å; A149-Y152 PolarHBondContact O-N 2.94Å; A149-F153 HydrophobicContact CB-CD2 4.23Å; A149-F153 HydrophobicContact CB-CE2 3.95Å; A149-F153 WeakPolarHBondContact O-CB 3.34Å; A149-F153 WeakPolarHBondContact O-CD2 3.29Å; A149-F153 WeakPolarHBondContact O-CG 3.3Å; A149-F153 PolarHBondContact O-N 3.39Å; A149-W188 HydrophobicContact CB-CH2 4.39Å; A149-W188 HydrophobicContact CB-CZ3 4.38Å
150	S	95.9	Very high	93.8	Very high	0 Å²	0	10.7 Å²	10.7	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-61.9	-48.2	177	-61.6	0	0	0	0	111.8	L105 D109 N146 Y148 Y152 F153 L154 N321	L105-S150 WeakPolarHBondContact CD1-OG 3.18Å; D109-S150 PolarHBondContact OD1-OG 3.3Å; N146-S150 PolarHBondContact ND2-OG 3.46Å; N146-S150 WeakPolarHBondContact O-CB 3.08Å; N146-S150 PolarHBondContact O-N 2.86Å; N146-S150 PolarHBondContact O-OG 3.11Å; N146-S150 VanDerWaalsContact O-OG 3.08Å; Y148-S150 VanDerWaalsContact C-N 3.28Å; Y148-S150 PolarHBondContact O-N 2.69Å; S150-Y152 VanDerWaalsContact C-N 3.33Å; S150-Y152 PolarHBondContact O-N 3.38Å; S150-F153 PolarHBondContact O-N 2.92Å; S150-L154 WeakPolarHBondContact O-CB 3.35Å; S150-L154 WeakPolarHBondContact O-CD1 3.45Å; S150-L154 WeakPolarHBondContact O-CG 3.43Å; S150-L154 PolarHBondContact O-N 3.05Å; S150-N321 WeakPolarHBondContact CB-ND2 3.49Å; S150-N321 PolarHBondContact OG-ND2 2.98Å
151	I	95.1	Very high	93.7	Very high	0 Å²	0	11.8 Å²	11.8	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-52.3	-50.4	174.2	-74.4	162.3	0	0	0	111.4	M147 Y148 L154 T155 F233 P236 F276 F280	M147-I151 HydrophobicContact CG-CD1 4.02Å; M147-I151 WeakPolarHBondContact O-CD1 3.47Å; M147-I151 VanDerWaalsContact O-CG1 3.25Å; M147-I151 WeakPolarHBondContact O-CG1 3.41Å; M147-I151 PolarHBondContact O-N 3.07Å; Y148-I151 HydrophobicContact CD1-CD1 4.3Å; Y148-I151 PolarHBondContact O-N 3.32Å; I151-L154 PolarHBondContact O-N 3.5Å; I151-T155 PolarHBondContact O-N 2.96Å; I151-T155 PolarHBondContact O-OG1 3Å; I151-F233 HydrophobicContact CD1-CD2 4.06Å; I151-P236 HydrophobicContact CG2-CB 3.5Å; I151-P236 VanDerWaalsContact CG2-CB 3.5Å; I151-P236 HydrophobicContact CG2-CG 3.31Å; I151-F276 HydrophobicContact CB-CE1 4.5Å; I151-F276 HydrophobicContact CG1-CE1 4.26Å; I151-F276 HydrophobicContact CG2-CE1 3.94Å; I151-F276 HydrophobicContact CG2-CZ 4.16Å; I151-F280 HydrophobicContact CD1-CB 4.28Å; I151-F280 HydrophobicContact CD1-CD1 3.85Å; I151-F280 HydrophobicContact CD1-CD2 4.39Å; I151-F280 HydrophobicContact CD1-CE1 4.27Å; I151-F280 HydrophobicContact CD1-CG 3.92Å; I151-F280 HydrophobicContact CG1-CB 4.43Å; I151-F280 HydrophobicContact CG1-CD1 3.84Å; I151-F280 HydrophobicContact CG1-CD2 3.67Å; I151-F280 HydrophobicContact CG1-CE1 3.95Å; I151-F280 HydrophobicContact CG1-CE2 3.8Å; I151-F280 HydrophobicContact CG1-CG 3.72Å; I151-F280 HydrophobicContact CG1-CZ 3.93Å
152	Y	95.9	Very high	93.6	Very high	39 Å²	39	12 Å²	12	15%	0.153	6%	0.063	C	C	.	.	H	α-helix	trans	-70.1	-39.3	-177.4	-71	-63.4	0	0	0	112.7	Y148 A149 S150 T155 C156 L187 V191 A232 F235 P236	Y148-Y152 WeakPolarHBondContact O-CD2 3.32Å; Y148-Y152 PolarHBondContact O-N 3.01Å; A149-Y152 PolarHBondContact O-N 2.94Å; S150-Y152 VanDerWaalsContact C-N 3.33Å; S150-Y152 PolarHBondContact O-N 3.38Å; Y152-T155 WeakPolarHBondContact O-CB 3.43Å; Y152-T155 PolarHBondContact O-N 3.23Å; Y152-C156 PolarHBondContact O-N 3.09Å; Y152-C156 PolarHBondContact O-SG 3.32Å; Y152-C156 VanDerWaalsContact O-SG 3.42Å; Y152-L187 HydrophobicContact CD1-CD2 4.28Å; Y152-L187 HydrophobicContact CG-CD2 3.99Å; Y152-V191 HydrophobicContact CD2-CG2 3.68Å; Y152-V191 HydrophobicContact CE2-CG2 3.92Å; Y152-A232 PolarHBondContact OH-O 3.38Å; Y152-A232 VanDerWaalsContact OH-O 3.14Å; Y152-F235 HydrophobicContact CE1-CD1 4.44Å; Y152-P236 HydrophobicContact CD1-CB 4.21Å; Y152-P236 HydrophobicContact CD1-CG 4.32Å; Y152-P236 HydrophobicContact CE1-CB 4.22Å; Y152-P236 HydrophobicContact CE1-CG 3.91Å
153	F	95.2	Very high	93.3	Very high	1 Å²	1	11.9 Å²	11.9	0%	0.004	6%	0.063	C	C	.	.	H	α-helix	trans	-65.2	-39.9	175.8	-71.4	-47.6	0	0	0	111.9	F101 H104 L105 A149 S150 T155 C156 I157 C184 L187 W188	F101-F153 HydrophobicContact CD1-CD1 4.21Å; H104-F153 HydrophobicContact CB-CD1 4.33Å; H104-F153 HydrophobicContact CB-CD2 4.32Å; H104-F153 HydrophobicContact CB-CE1 3.79Å; H104-F153 HydrophobicContact CB-CE2 3.76Å; H104-F153 HydrophobicContact CB-CZ 3.5Å; H104-F153 VanDerWaalsContact CB-CZ 3.5Å; L105-F153 HydrophobicContact CB-CB 4.34Å; L105-F153 HydrophobicContact CD1-CB 4.23Å; A149-F153 HydrophobicContact CB-CD2 4.23Å; A149-F153 HydrophobicContact CB-CE2 3.95Å; A149-F153 WeakPolarHBondContact O-CB 3.34Å; A149-F153 WeakPolarHBondContact O-CD2 3.29Å; A149-F153 WeakPolarHBondContact O-CG 3.3Å; A149-F153 PolarHBondContact O-N 3.39Å; S150-F153 PolarHBondContact O-N 2.92Å; F153-T155 VanDerWaalsContact C-N 3.32Å; F153-T155 PolarHBondContact O-N 3.29Å; F153-C156 WeakPolarHBondContact O-CB 3.39Å; F153-C156 PolarHBondContact O-N 2.94Å; F153-I157 WeakPolarHBondContact O-CD1 3.32Å; F153-I157 VanDerWaalsContact O-CG1 3.23Å; F153-I157 WeakPolarHBondContact O-CG1 3.32Å; F153-I157 PolarHBondContact O-N 3.33Å; F153-C184 HydrophobicContact CE1-CB 4.01Å; F153-C184 HydrophobicContact CZ-CB 4.5Å; F153-L187 HydrophobicContact CD1-CD1 4.15Å; F153-L187 HydrophobicContact CE1-CB 4.5Å; F153-L187 HydrophobicContact CE1-CD1 4Å; F153-W188 AromaticContact CE2-CZ2 3.95Å; F153-W188 HydrophobicContact CE2-CZ2 3.95Å; F153-W188 AromaticContact CZ-CE2 3.91Å; F153-W188 HydrophobicContact CZ-CZ2 4.28Å; F153-W188 AromaticContact CZ-NE1 3.55Å
154	L	92.6	Very high	93	Very high	0 Å²	0	12.5 Å²	12.5	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-61.4	-40.1	173.1	-68.2	169.8	0	0	0	111.7	L105 S150 I151 I157 S158 V272 I275 F276 F280 M328	L105-L154 HydrophobicContact CD2-CD2 4.19Å; S150-L154 WeakPolarHBondContact O-CB 3.35Å; S150-L154 WeakPolarHBondContact O-CD1 3.45Å; S150-L154 WeakPolarHBondContact O-CG 3.43Å; S150-L154 PolarHBondContact O-N 3.05Å; I151-L154 PolarHBondContact O-N 3.5Å; L154-I157 PolarHBondContact O-N 3.07Å; L154-S158 WeakPolarHBondContact O-CB 3.21Å; L154-S158 PolarHBondContact O-N 3.48Å; L154-S158 PolarHBondContact O-OG 3.48Å; L154-V272 HydrophobicContact CB-CG1 4.43Å; L154-V272 HydrophobicContact CD2-CG2 4.33Å; L154-I275 HydrophobicContact CD1-CG2 3.87Å; L154-F276 HydrophobicContact CB-CE2 3.99Å; L154-F276 HydrophobicContact CB-CZ 4.36Å; L154-F276 HydrophobicContact CD1-CE2 4.44Å; L154-F280 HydrophobicContact CD1-CE2 3.71Å; L154-F280 HydrophobicContact CD1-CZ 4.35Å; L154-M328 HydrophobicContact CD2-CE 3.17Å; L154-M328 HydrophobicContact CD2-SD 3.92Å
155	T	94.1	Very high	92.8	Very high	11 Å²	11	12.1 Å²	12.1	7%	0.067	7%	0.067	C	C	.	.	H	α-helix	trans	-64.6	-43	173	-64	0	0	0	0	111.7	I151 Y152 F153 I157 S158 A159 P236 T239 T240	I151-T155 PolarHBondContact O-N 2.96Å; I151-T155 PolarHBondContact O-OG1 3Å; Y152-T155 WeakPolarHBondContact O-CB 3.43Å; Y152-T155 PolarHBondContact O-N 3.23Å; F153-T155 VanDerWaalsContact C-N 3.32Å; F153-T155 PolarHBondContact O-N 3.29Å; T155-I157 VanDerWaalsContact C-N 3.35Å; T155-I157 PolarHBondContact O-N 3.19Å; T155-S158 WeakPolarHBondContact O-CB 3.36Å; T155-S158 PolarHBondContact O-N 3.3Å; T155-A159 WeakPolarHBondContact O-CB 3.31Å; T155-A159 PolarHBondContact O-N 3.11Å; T155-P236 HydrophobicContact CG2-CB 4.33Å; T155-P236 WeakPolarHBondContact OG1-CB 3.07Å; T155-P236 PolarHBondContact OG1-O 3.32Å; T155-T239 HydrophobicContact CG2-CG2 3.65Å; T155-T240 PolarHBondContact OG1-OG1 3.39Å
156	C	94.4	Very high	92.5	Very high	30 Å²	30	13 Å²	13	20%	0.203	7%	0.073	C	C	.	.	H	α-helix	trans	-61.8	-40.5	175.1	-74	0	0	0	0	112.6	F101 Y152 F153 S158 A159 D160	F101-C156 HydrophobicContact CD1-CB 3.8Å; F101-C156 HydrophobicContact CD2-CB 4Å; F101-C156 HydrophobicContact CE1-CB 3.73Å; F101-C156 HydrophobicContact CE2-CB 3.92Å; F101-C156 HydrophobicContact CG-CB 3.97Å; F101-C156 HydrophobicContact CZ-CB 3.8Å; Y152-C156 PolarHBondContact O-N 3.09Å; Y152-C156 PolarHBondContact O-SG 3.32Å; Y152-C156 VanDerWaalsContact O-SG 3.42Å; F153-C156 WeakPolarHBondContact O-CB 3.39Å; F153-C156 PolarHBondContact O-N 2.94Å; C156-S158 VanDerWaalsContact C-N 3.31Å; C156-S158 PolarHBondContact O-N 2.55Å; C156-A159 PolarHBondContact O-N 3.29Å; C156-D160 WeakPolarHBondContact O-CB 3.38Å; C156-D160 PolarHBondContact O-N 3.35Å
157	I	91.7	Very high	92.2	Very high	0 Å²	0	16.3 Å²	16.3	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-62.6	-41.4	174.3	-69.1	161.4	0	0	0	110.5	F101 L102 L105 F153 L154 T155 D160 R161 M268 M328	F101-I157 HydrophobicContact CB-CD1 4.12Å; F101-I157 HydrophobicContact CB-CG1 3.6Å; F101-I157 HydrophobicContact CD2-CG1 4.34Å; F101-I157 HydrophobicContact CG-CG1 4.34Å; L102-I157 HydrophobicContact CD2-CD1 3.57Å; L102-I157 HydrophobicContact CG-CD1 4.21Å; L105-I157 HydrophobicContact CD2-CD1 4.37Å; F153-I157 WeakPolarHBondContact O-CD1 3.32Å; F153-I157 VanDerWaalsContact O-CG1 3.23Å; F153-I157 WeakPolarHBondContact O-CG1 3.32Å; F153-I157 PolarHBondContact O-N 3.33Å; L154-I157 PolarHBondContact O-N 3.07Å; T155-I157 VanDerWaalsContact C-N 3.35Å; T155-I157 PolarHBondContact O-N 3.19Å; I157-D160 PolarHBondContact O-N 3Å; I157-R161 PolarHBondContact O-N 3.4Å; I157-R161 VanDerWaalsContact O-N 3.09Å; I157-M268 HydrophobicContact CG2-CE 3.48Å; I157-M268 VanDerWaalsContact CG2-CE 3.48Å; I157-M268 HydrophobicContact CG2-SD 3.79Å; I157-M328 HydrophobicContact CD1-SD 4.02Å
158	S	90.9	Very high	91.7	Very high	0 Å²	0	19.6 Å²	19.6	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-62.7	-44.1	175.7	-54.6	0	0	0	0	111.7	L154 T155 C156 R161 F162 Y244	L154-S158 WeakPolarHBondContact O-CB 3.21Å; L154-S158 PolarHBondContact O-N 3.48Å; L154-S158 PolarHBondContact O-OG 3.48Å; T155-S158 WeakPolarHBondContact O-CB 3.36Å; T155-S158 PolarHBondContact O-N 3.3Å; C156-S158 VanDerWaalsContact C-N 3.31Å; C156-S158 PolarHBondContact O-N 2.55Å; S158-R161 PolarHBondContact O-N 2.89Å; S158-F162 WeakPolarHBondContact O-CB 3.09Å; S158-F162 PolarHBondContact O-N 3.08Å; S158-Y244 VanDerWaalsContact OG-CZ 3.24Å; S158-Y244 PolarHBondContact OG-OH 3.06Å
159	A	92.1	Very high	91.3	Very high	31 Å²	31	24.6 Å²	24.6	26%	0.256	14%	0.141	S	C	.	.	H	α-helix	trans	-66	-41	176.4	0	0	0	0	0	112.4	T155 C156 R161 F162 L163	T155-A159 WeakPolarHBondContact O-CB 3.31Å; T155-A159 PolarHBondContact O-N 3.11Å; C156-A159 PolarHBondContact O-N 3.29Å; A159-R161 VanDerWaalsContact C-N 3.3Å; A159-R161 PolarHBondContact O-N 2.61Å; A159-F162 WeakPolarHBondContact O-CB 3.09Å; A159-F162 PolarHBondContact O-N 3.03Å; A159-L163 WeakPolarHBondContact O-CG 3.33Å; A159-L163 PolarHBondContact O-N 3.25Å
160	D	90.8	Very high	90.9	Very high	7 Å²	7	31 Å²	31	4%	0.037	17%	0.168	C	C	.	.	H	α-helix	trans	-57.6	-43.8	173.6	176.3	69.7	0	0	0	111.2	F101 C156 I157 A164 R175	F101-D160 HydrophobicContact CE2-CB 4.43Å; C156-D160 WeakPolarHBondContact O-CB 3.38Å; C156-D160 PolarHBondContact O-N 3.35Å; I157-D160 PolarHBondContact O-N 3Å; D160-A164 WeakPolarHBondContact O-CB 2.94Å; D160-A164 PolarHBondContact O-N 2.82Å; D160-R175 IonicContact OD1-CZ 3.12Å; D160-R175 IonicContact OD1-NE 2.72Å; D160-R175 PolarHBondContact OD1-NE 3.46Å; D160-R175 IonicContact OD1-NH2 3.46Å; D160-R175 PolarHBondContact OD1-NH2 2.91Å; D160-R175 IonicContact OD2-CZ 3.47Å; D160-R175 IonicContact OD2-NE 3.67Å; D160-R175 IonicContact OD2-NH2 3.3Å; D160-R175 PolarHBondContact OD2-NH2 2.8Å
161	R	88.8	Confident	90.5	Very high	22 Å²	22	31.7 Å²	31.7	8%	0.083	17%	0.173	C	C	.	.	H	α-helix	trans	-67.8	-42.2	176	-71.1	-50.8	108.3	177.8	11.4	112.8	I157 S158 A159 L163 A164 I165 R175 I247 M268	I157-R161 PolarHBondContact O-N 3.4Å; I157-R161 VanDerWaalsContact O-N 3.09Å; S158-R161 PolarHBondContact O-N 2.89Å; A159-R161 VanDerWaalsContact C-N 3.3Å; A159-R161 PolarHBondContact O-N 2.61Å; R161-L163 VanDerWaalsContact C-N 3.33Å; R161-L163 PolarHBondContact O-N 3.44Å; R161-A164 PolarHBondContact O-N 3.26Å; R161-I165 WeakPolarHBondContact O-CG1 3.04Å; R161-I165 PolarHBondContact O-N 2.96Å; R161-I165 VanDerWaalsContact O-N 3.11Å; R161-R175 VanDerWaalsContact NH2-NH2 3.15Å; R161-I247 HydrophobicContact CB-CD1 4.25Å; R161-M268 HydrophobicContact CB-CE 4.1Å; R161-M268 HydrophobicContact CG-CE 3.17Å; R161-M268 HydrophobicContact CG-SD 3.53Å; R161-M268 VanDerWaalsContact CG-SD 3.53Å
162	F	90.6	Very high	90	Very high	32 Å²	32	38.3 Å²	38.3	14%	0.14	21%	0.208	C	C	.	.	H	α-helix	trans	-56	-49.5	175.6	164.8	-100.8	0	0	0	110.9	S158 A159 A164 I165 V166 H167 C243 L246 I247	S158-F162 WeakPolarHBondContact O-CB 3.09Å; S158-F162 PolarHBondContact O-N 3.08Å; A159-F162 WeakPolarHBondContact O-CB 3.09Å; A159-F162 PolarHBondContact O-N 3.03Å; F162-A164 VanDerWaalsContact C-N 3.33Å; F162-A164 PolarHBondContact O-N 3.31Å; F162-I165 PolarHBondContact O-N 2.9Å; F162-V166 HydrophobicContact CD2-CB 3.9Å; F162-V166 HydrophobicContact CD2-CG1 4.47Å; F162-V166 HydrophobicContact CD2-CG2 3.57Å; F162-V166 HydrophobicContact CE2-CB 3.61Å; F162-V166 HydrophobicContact CE2-CG1 3.71Å; F162-V166 HydrophobicContact CE2-CG2 3.63Å; F162-V166 HydrophobicContact CZ-CB 4.2Å; F162-V166 HydrophobicContact CZ-CG1 4.15Å; F162-V166 WeakPolarHBondContact O-CB 3.28Å; F162-V166 PolarHBondContact O-N 3.4Å; F162-H167 AromaticContact CE1-CD2 3.72Å; F162-H167 AromaticContact CZ-CD2 3.64Å; F162-H167 AromaticContact CZ-NE2 3.64Å; F162-C243 HydrophobicContact CB-CB 4.03Å; F162-C243 HydrophobicContact CG-CB 4.42Å; F162-L246 HydrophobicContact CD2-CB 4.05Å; F162-L246 HydrophobicContact CD2-CD1 4.42Å; F162-L246 HydrophobicContact CE2-CB 3.66Å; F162-L246 HydrophobicContact CE2-CD1 3.58Å; F162-L246 HydrophobicContact CE2-CG 4.28Å; F162-L246 HydrophobicContact CZ-CD1 4.01Å; F162-I247 HydrophobicContact CB-CD1 4.04Å; F162-I247 HydrophobicContact CB-CG1 4.23Å; F162-I247 HydrophobicContact CD2-CG1 4.26Å
163	L	90.3	Very high	89.7	Confident	35 Å²	35	44.1 Å²	44.1	18%	0.183	23%	0.234	C	C	.	.	H	α-helix	trans	-60.2	-42.2	177.3	-71.9	171	0	0	0	112.2	A159 R161 I165 H167 S171 L174	A159-L163 WeakPolarHBondContact O-CG 3.33Å; A159-L163 PolarHBondContact O-N 3.25Å; R161-L163 VanDerWaalsContact C-N 3.33Å; R161-L163 PolarHBondContact O-N 3.44Å; L163-I165 VanDerWaalsContact C-N 3.3Å; L163-I165 PolarHBondContact O-N 3.41Å; L163-H167 CarbonylContact O-C 3.17Å; L163-H167 PolarHBondContact O-N 3.36Å; L163-H167 VanDerWaalsContact O-O 3.13Å; L163-S171 WeakPolarHBondContact O-CB 3.02Å; L163-L174 HydrophobicContact CD1-CD2 3.78Å; L163-L174 HydrophobicContact CD1-CG 4.4Å; L163-L174 HydrophobicContact CD2-CD2 4.18Å
164	A	87.9	Confident	89.3	Confident	14 Å²	14	48.4 Å²	48.4	12%	0.116	26%	0.256	C	S	.	.	H	α-helix	trans	-62.7	-33.8	-179.8	0	0	0	0	0	113.6	D160 R161 F162	D160-A164 WeakPolarHBondContact O-CB 2.94Å; D160-A164 PolarHBondContact O-N 2.82Å; R161-A164 PolarHBondContact O-N 3.26Å; F162-A164 VanDerWaalsContact C-N 3.33Å; F162-A164 PolarHBondContact O-N 3.31Å
165	I	87.1	Confident	89.3	Confident	4 Å²	4	51.6 Å²	51.6	2%	0.021	27%	0.268	C	S	.	.	H	α-helix	trans	-100	-47.8	-171.6	-62.8	167.7	0	0	0	111.6	R161 F162 L163 I247 L251 V257 A265	R161-I165 WeakPolarHBondContact O-CG1 3.04Å; R161-I165 PolarHBondContact O-N 2.96Å; R161-I165 VanDerWaalsContact O-N 3.11Å; F162-I165 PolarHBondContact O-N 2.9Å; L163-I165 VanDerWaalsContact C-N 3.3Å; L163-I165 PolarHBondContact O-N 3.41Å; I165-I247 HydrophobicContact CD1-CG2 3.9Å; I165-I247 HydrophobicContact CG2-CG2 4.38Å; I165-L251 HydrophobicContact CG2-CD2 4.09Å; I165-L251 HydrophobicContact CG2-CG 4.48Å; I165-V257 HydrophobicContact CG2-CG2 4.47Å; I165-A265 HydrophobicContact CD1-CB 3.33Å
166	V	89.1	Confident	89.1	Confident	33 Å²	33	57.6 Å²	57.6	20%	0.2	29%	0.29	C	S	.	.	H	α-helix	trans	-86.4	-29.2	-171.7	-175.3	0	0	0	0	111.6	F162 I247	F162-V166 HydrophobicContact CD2-CB 3.9Å; F162-V166 HydrophobicContact CD2-CG1 4.47Å; F162-V166 HydrophobicContact CD2-CG2 3.57Å; F162-V166 HydrophobicContact CE2-CB 3.61Å; F162-V166 HydrophobicContact CE2-CG1 3.71Å; F162-V166 HydrophobicContact CE2-CG2 3.63Å; F162-V166 HydrophobicContact CZ-CB 4.2Å; F162-V166 HydrophobicContact CZ-CG1 4.15Å; F162-V166 WeakPolarHBondContact O-CB 3.28Å; F162-V166 PolarHBondContact O-N 3.4Å; V166-I247 HydrophobicContact CG2-CG1 4.08Å
167	H	88.1	Confident	88.8	Confident	70 Å²	70	59 Å²	59	32%	0.324	30%	0.298	S	S	.	.			trans	-129.8	61.8	-177.9	-64.3	-52.5	0	0	0	112.9	F162 L163 V169 K170 S171	F162-H167 AromaticContact CE1-CD2 3.72Å; F162-H167 AromaticContact CZ-CD2 3.64Å; F162-H167 AromaticContact CZ-NE2 3.64Å; L163-H167 CarbonylContact O-C 3.17Å; L163-H167 PolarHBondContact O-N 3.36Å; L163-H167 VanDerWaalsContact O-O 3.13Å; H167-V169 VanDerWaalsContact C-N 3.28Å; H167-V169 PolarHBondContact O-N 3.06Å; H167-V169 VanDerWaalsContact O-N 3.16Å; H167-K170 HydrophobicContact CB-CB 4.15Å; H167-K170 HydrophobicContact CB-CD 4.39Å; H167-K170 HydrophobicContact CB-CG 4.48Å; H167-K170 PolarHBondContact O-N 3.1Å; H167-K170 VanDerWaalsContact O-N 3.11Å; H167-S171 WeakPolarHBondContact O-CB 3.28Å; H167-S171 PolarHBondContact O-N 3.35Å
168	P	84.4	Confident	88.8	Confident	68 Å²	68	64.3 Å²	64.3	44%	0.442	33%	0.326	S	S	.	.	H	α-helix	trans	-56.9	-37.5	-172.3	22.3	-33.8	0	0	0	113.6	S171 L172	P168-S171 WeakPolarHBondContact O-CB 3.22Å; P168-S171 PolarHBondContact O-N 2.69Å; P168-L172 PolarHBondContact O-N 3.05Å
169	V	86.6	Confident	89	Confident	116 Å²	116	69.7 Å²	69.7	70%	0.703	35%	0.347	S	S	*	.	H	α-helix	trans	-67.8	-45.5	178.3	-178.1	0	0	0	0	112	H167 S171 L172	H167-V169 VanDerWaalsContact C-N 3.28Å; H167-V169 PolarHBondContact O-N 3.06Å; H167-V169 VanDerWaalsContact O-N 3.16Å; V169-S171 VanDerWaalsContact C-N 3.28Å; V169-S171 PolarHBondContact O-N 3.3Å; V169-L172 PolarHBondContact O-N 2.96Å
170	K	87.8	Confident	89.1	Confident	137 Å²	137	68.3 Å²	68.3	60%	0.596	34%	0.336	S	S	*	.	H	α-helix	trans	-66.2	-34.5	176.1	-66.2	-175.1	177.7	179.8	0	111.2	H167 L172 K173 L174	H167-K170 HydrophobicContact CB-CB 4.15Å; H167-K170 HydrophobicContact CB-CD 4.39Å; H167-K170 HydrophobicContact CB-CG 4.48Å; H167-K170 PolarHBondContact O-N 3.1Å; H167-K170 VanDerWaalsContact O-N 3.11Å; K170-L172 PolarHBondContact O-N 3.06Å; K170-K173 PolarHBondContact O-N 3.46Å; K170-L174 PolarHBondContact O-N 3.08Å
171	S	86.6	Confident	89.2	Confident	15 Å²	15	72 Å²	72	11%	0.105	35%	0.353	C	S	.	.	H	α-helix	trans	-55.3	-35.9	178	145.1	0	0	0	0	112.6	L163 H167 P168 V169 K173 L174 R175	L163-S171 WeakPolarHBondContact O-CB 3.02Å; H167-S171 WeakPolarHBondContact O-CB 3.28Å; H167-S171 PolarHBondContact O-N 3.35Å; P168-S171 WeakPolarHBondContact O-CB 3.22Å; P168-S171 PolarHBondContact O-N 2.69Å; V169-S171 VanDerWaalsContact C-N 3.28Å; V169-S171 PolarHBondContact O-N 3.3Å; S171-K173 VanDerWaalsContact C-N 3.25Å; S171-K173 PolarHBondContact O-N 3.38Å; S171-L174 PolarHBondContact O-N 3.33Å; S171-R175 VanDerWaalsContact O-CB 3.29Å; S171-R175 WeakPolarHBondContact O-CB 3.42Å; S171-R175 PolarHBondContact O-N 2.84Å; S171-R175 WeakPolarHBondContact OG-CD 3.36Å
172	L	84.7	Confident	89.6	Confident	139 Å²	139	75.8 Å²	75.8	73%	0.728	37%	0.374	S	S	*	.	H	α-helix	trans	-59.6	-33.3	176.4	-64.4	173.4	0	0	0	113.5	P168 V169 K170	P168-L172 PolarHBondContact O-N 3.05Å; V169-L172 PolarHBondContact O-N 2.96Å; K170-L172 PolarHBondContact O-N 3.06Å
173	K	88.9	Confident	89.9	Confident	162 Å²	162	75.8 Å²	75.8	70%	0.704	38%	0.38	S	S	*	.	H	α-helix	trans	-90.1	-38	179.7	-65.1	-174.7	179.8	-177.3	0	112.2	K170 S171 R176	K170-K173 PolarHBondContact O-N 3.46Å; S171-K173 VanDerWaalsContact C-N 3.25Å; S171-K173 PolarHBondContact O-N 3.38Å; K173-R176 PolarHBondContact O-NE 3.07Å
174	L	88.8	Confident	90.2	Very high	91 Å²	91	74.1 Å²	74.1	48%	0.476	37%	0.372	S	S	.	.	H	α-helix	trans	-95.2	-25.2	-167.2	-159.9	62.9	0	0	0	114.2	L163 K170 S171 R176 Y179	L163-L174 HydrophobicContact CD1-CD2 3.78Å; L163-L174 HydrophobicContact CD1-CG 4.4Å; L163-L174 HydrophobicContact CD2-CD2 4.18Å; K170-L174 PolarHBondContact O-N 3.08Å; S171-L174 PolarHBondContact O-N 3.33Å; L174-R176 PolarHBondContact O-N 3.43Å; L174-Y179 HydrophobicContact CD1-CD2 4.35Å; L174-Y179 HydrophobicContact CD1-CE2 4.46Å; L174-Y179 WeakPolarHBondContact O-CD2 3.5Å
175	R	91.3	Very high	90.6	Very high	67 Å²	67	76 Å²	76	25%	0.253	39%	0.387	S	S	.	.			trans	-83.8	58.2	179.5	-65.5	-178.7	74.3	-139.7	-2.2	111.7	P97 D160 R161 S171	P97-R175 HydrophobicContact CG-CB 4Å; P97-R175 WeakPolarHBondContact CG-O 3.34Å; D160-R175 IonicContact OD1-CZ 3.12Å; D160-R175 IonicContact OD1-NE 2.72Å; D160-R175 PolarHBondContact OD1-NE 3.46Å; D160-R175 IonicContact OD1-NH2 3.46Å; D160-R175 PolarHBondContact OD1-NH2 2.91Å; D160-R175 IonicContact OD2-CZ 3.47Å; D160-R175 IonicContact OD2-NE 3.67Å; D160-R175 IonicContact OD2-NH2 3.3Å; D160-R175 PolarHBondContact OD2-NH2 2.8Å; R161-R175 VanDerWaalsContact NH2-NH2 3.15Å; S171-R175 VanDerWaalsContact O-CB 3.29Å; S171-R175 WeakPolarHBondContact O-CB 3.42Å; S171-R175 PolarHBondContact O-N 2.84Å; S171-R175 WeakPolarHBondContact OG-CD 3.36Å
176	R	90.3	Very high	91.1	Very high	137 Å²	137	82.3 Å²	82.3	52%	0.517	42%	0.415	S	S	.	.			trans	-100	142.2	176.2	-65.9	-174.1	176.8	-161.7	-2.4	111.4	K173 L174 L178 Y179 A180	K173-R176 PolarHBondContact O-NE 3.07Å; L174-R176 PolarHBondContact O-N 3.43Å; R176-L178 PolarHBondContact O-N 3.42Å; R176-Y179 HydrophobicContact CB-CD2 3.82Å; R176-Y179 HydrophobicContact CB-CE2 4.22Å; R176-Y179 HydrophobicContact CB-CG 4.49Å; R176-Y179 HydrophobicContact CG-CD2 4.36Å; R176-Y179 HydrophobicContact CG-CE2 4.34Å; R176-Y179 PolarHBondContact O-N 3.12Å; R176-A180 PolarHBondContact O-N 3.4Å
177	P	89.1	Confident	91.4	Very high	59 Å²	59	81.8 Å²	81.8	38%	0.383	41%	0.41	S	S	.	.	H	α-helix	trans	-60	-36.4	179.8	-8.4	17.3	0	0	0	112.1	G95 Y179 A180 H181	G95-P177 WeakPolarHBondContact O-CB 3.33Å; G95-P177 WeakPolarHBondContact O-CG 3.43Å; P177-Y179 PolarHBondContact O-N 3.35Å; P177-A180 WeakPolarHBondContact O-CB 3.39Å; P177-A180 PolarHBondContact O-N 3.09Å; P177-A180 VanDerWaalsContact O-N 3.12Å; P177-H181 PolarHBondContact O-CD2 2.95Å; P177-H181 VanDerWaalsContact O-CD2 3.25Å; P177-H181 PolarHBondContact O-N 3.26Å
178	L	91.5	Very high	91.9	Very high	111 Å²	111	80.9 Å²	80.9	58%	0.581	40%	0.404	S	S	*	.	H	α-helix	trans	-56.3	-47.7	177.2	179	62.8	0	0	0	112.1	R176 A180 H181 L182	R176-L178 PolarHBondContact O-N 3.42Å; L178-A180 VanDerWaalsContact C-N 3.27Å; L178-A180 PolarHBondContact O-N 3.36Å; L178-H181 PolarHBondContact O-N 2.84Å; L178-L182 HydrophobicContact CD1-CD1 4.49Å; L178-L182 HydrophobicContact CD1-CG 4.46Å; L178-L182 HydrophobicContact CG-CD1 4.27Å; L178-L182 WeakPolarHBondContact O-CG 3.44Å; L178-L182 PolarHBondContact O-N 3.32Å
179	Y	93.9	Very high	92.5	Very high	113 Å²	113	82.1 Å²	82.1	44%	0.443	41%	0.411	S	S	.	.	H	α-helix	trans	-66.2	-31.9	178.7	-62	-40.6	0	0	0	112.1	L174 R176 P177 L182 A183	L174-Y179 HydrophobicContact CD1-CD2 4.35Å; L174-Y179 HydrophobicContact CD1-CE2 4.46Å; L174-Y179 WeakPolarHBondContact O-CD2 3.5Å; R176-Y179 HydrophobicContact CB-CD2 3.82Å; R176-Y179 HydrophobicContact CB-CE2 4.22Å; R176-Y179 HydrophobicContact CB-CG 4.49Å; R176-Y179 HydrophobicContact CG-CD2 4.36Å; R176-Y179 HydrophobicContact CG-CE2 4.34Å; R176-Y179 PolarHBondContact O-N 3.12Å; P177-Y179 PolarHBondContact O-N 3.35Å; Y179-L182 HydrophobicContact CD1-CD1 4.39Å; Y179-A183 VanDerWaalsContact O-CB 3.29Å; Y179-A183 WeakPolarHBondContact O-CB 3.18Å; Y179-A183 PolarHBondContact O-N 3.41Å
180	A	94.1	Very high	92.8	Very high	2 Å²	2	79.4 Å²	79.4	2%	0.017	39%	0.394	C	S	.	.	H	α-helix	trans	-65.6	-45.9	172.6	0	0	0	0	0	111.5	P97 V100 F101 R176 P177 L178 L182 A183 C184	P97-A180 HydrophobicContact CB-CB 3.9Å; V100-A180 HydrophobicContact CB-CB 3.84Å; V100-A180 HydrophobicContact CG1-CB 3.86Å; V100-A180 HydrophobicContact CG2-CB 4.29Å; F101-A180 HydrophobicContact CE1-CB 4Å; F101-A180 HydrophobicContact CE2-CB 4.21Å; F101-A180 HydrophobicContact CZ-CB 3.76Å; R176-A180 PolarHBondContact O-N 3.4Å; P177-A180 WeakPolarHBondContact O-CB 3.39Å; P177-A180 PolarHBondContact O-N 3.09Å; P177-A180 VanDerWaalsContact O-N 3.12Å; L178-A180 VanDerWaalsContact C-N 3.27Å; L178-A180 PolarHBondContact O-N 3.36Å; A180-L182 PolarHBondContact O-N 2.81Å; A180-A183 PolarHBondContact O-N 3.47Å; A180-C184 WeakPolarHBondContact O-CB 3.25Å; A180-C184 PolarHBondContact O-N 3.42Å; A180-C184 PolarHBondContact O-SG 3.17Å
181	H	94.3	Very high	93.1	Very high	84 Å²	84	73 Å²	73	39%	0.389	37%	0.366	S	S	.	.	H	α-helix	trans	-61.9	-42.2	176.3	-75.9	-63.3	0	0	0	112.7	V100 H104 P177 L178 C184 A185	V100-H181 WeakPolarHBondContact CG1-ND1 3.25Å; H104-H181 AromaticContact NE2-ND1 3.99Å; P177-H181 PolarHBondContact O-CD2 2.95Å; P177-H181 VanDerWaalsContact O-CD2 3.25Å; P177-H181 PolarHBondContact O-N 3.26Å; L178-H181 PolarHBondContact O-N 2.84Å; H181-C184 PolarHBondContact O-N 3.49Å; H181-A185 WeakPolarHBondContact O-CB 3.41Å; H181-A185 PolarHBondContact O-N 3.3Å
182	L	96	Very high	93.4	Very high	102 Å²	102	73.9 Å²	73.9	53%	0.534	38%	0.375	S	S	.	.	H	α-helix	trans	-62.6	-44.4	175.5	-68.8	175	0	0	0	111.6	L178 Y179 A180 A185 F186	L178-L182 HydrophobicContact CD1-CD1 4.49Å; L178-L182 HydrophobicContact CD1-CG 4.46Å; L178-L182 HydrophobicContact CG-CD1 4.27Å; L178-L182 WeakPolarHBondContact O-CG 3.44Å; L178-L182 PolarHBondContact O-N 3.32Å; Y179-L182 HydrophobicContact CD1-CD1 4.39Å; A180-L182 PolarHBondContact O-N 2.81Å; L182-A185 PolarHBondContact O-N 3.47Å; L182-F186 WeakPolarHBondContact O-CB 3.49Å; L182-F186 PolarHBondContact O-N 3.43Å
183	A	96.1	Very high	93.8	Very high	33 Å²	33	72 Å²	72	27%	0.273	37%	0.369	S	S	.	.	H	α-helix	trans	-61.7	-43.5	175.2	0	0	0	0	0	111.6	F101 Y179 A180 F186 L187	F101-A183 HydrophobicContact CE1-CB 4.2Å; Y179-A183 VanDerWaalsContact O-CB 3.29Å; Y179-A183 WeakPolarHBondContact O-CB 3.18Å; Y179-A183 PolarHBondContact O-N 3.41Å; A180-A183 PolarHBondContact O-N 3.47Å; A183-F186 PolarHBondContact O-N 3.45Å; A183-L187 WeakPolarHBondContact O-CB 3.38Å; A183-L187 VanDerWaalsContact O-CG 3.27Å; A183-L187 WeakPolarHBondContact O-CG 3.46Å; A183-L187 PolarHBondContact O-N 3.2Å
184	C	96.9	Very high	93.8	Very high	0 Å²	0	67 Å²	67	0%	0	36%	0.357	C	S	.	.	H	α-helix	trans	-61.6	-47.6	175.9	-66.6	0	0	0	0	112	F101 H104 F153 A180 H181 F186 L187 W188	F101-C184 WeakPolarHBondContact CD1-SG 3.23Å; H104-C184 VanDerWaalsContact CD2-CB 3.5Å; H104-C184 WeakPolarHBondContact CD2-CB 3.11Å; H104-C184 PolarHBondContact CD2-SG 3.29Å; F153-C184 HydrophobicContact CE1-CB 4.01Å; F153-C184 HydrophobicContact CZ-CB 4.5Å; A180-C184 WeakPolarHBondContact O-CB 3.25Å; A180-C184 PolarHBondContact O-N 3.42Å; A180-C184 PolarHBondContact O-SG 3.17Å; H181-C184 PolarHBondContact O-N 3.49Å; C184-F186 VanDerWaalsContact C-N 3.32Å; C184-F186 PolarHBondContact O-N 3.33Å; C184-L187 PolarHBondContact O-N 3.04Å; C184-W188 PolarHBondContact O-N 3.5Å
185	A	97.3	Very high	93.8	Very high	54 Å²	54	63.5 Å²	63.5	45%	0.446	34%	0.339	S	S	.	.	H	α-helix	trans	-59.3	-44.6	178.3	0	0	0	0	0	111.3	H181 L182 W188 V189	H181-A185 WeakPolarHBondContact O-CB 3.41Å; H181-A185 PolarHBondContact O-N 3.3Å; L182-A185 PolarHBondContact O-N 3.47Å; A185-W188 PolarHBondContact O-N 2.9Å; A185-V189 WeakPolarHBondContact O-CG2 3.21Å; A185-V189 PolarHBondContact O-N 3.2Å; A185-V189 VanDerWaalsContact O-N 3.14Å
186	F	97.4	Very high	93.7	Very high	136 Å²	136	62.2 Å²	62.2	60%	0.596	34%	0.342	S	S	*	.	H	α-helix	trans	-59.6	-48.6	174.4	174.6	-102.3	0	0	0	112.1	L182 A183 C184 W188 V189 V190	L182-F186 WeakPolarHBondContact O-CB 3.49Å; L182-F186 PolarHBondContact O-N 3.43Å; A183-F186 PolarHBondContact O-N 3.45Å; C184-F186 VanDerWaalsContact C-N 3.32Å; C184-F186 PolarHBondContact O-N 3.33Å; F186-W188 PolarHBondContact O-N 3.15Å; F186-V189 PolarHBondContact O-N 3.48Å; F186-V190 HydrophobicContact CD1-CG2 4.23Å; F186-V190 HydrophobicContact CD2-CG2 4.15Å; F186-V190 HydrophobicContact CE1-CG2 3.8Å; F186-V190 HydrophobicContact CE2-CG2 3.7Å; F186-V190 HydrophobicContact CG-CG2 4.4Å; F186-V190 HydrophobicContact CZ-CG2 3.52Å; F186-V190 WeakPolarHBondContact O-CG2 3.36Å; F186-V190 PolarHBondContact O-N 3.11Å
187	L	96.4	Very high	93.6	Very high	21 Å²	21	59.4 Å²	59.4	11%	0.11	34%	0.342	C	S	.	.	H	α-helix	trans	-61.3	-42.1	179.1	-73.6	175.3	0	0	0	112.2	Y152 F153 A183 C184 V189 V190 V191	Y152-L187 HydrophobicContact CD1-CD2 4.28Å; Y152-L187 HydrophobicContact CG-CD2 3.99Å; F153-L187 HydrophobicContact CD1-CD1 4.15Å; F153-L187 HydrophobicContact CE1-CB 4.5Å; F153-L187 HydrophobicContact CE1-CD1 4Å; A183-L187 WeakPolarHBondContact O-CB 3.38Å; A183-L187 VanDerWaalsContact O-CG 3.27Å; A183-L187 WeakPolarHBondContact O-CG 3.46Å; A183-L187 PolarHBondContact O-N 3.2Å; C184-L187 PolarHBondContact O-N 3.04Å; L187-V189 VanDerWaalsContact C-N 3.34Å; L187-V189 PolarHBondContact O-N 3.28Å; L187-V190 PolarHBondContact O-N 3.39Å; L187-V191 WeakPolarHBondContact O-CB 3.36Å; L187-V191 VanDerWaalsContact O-CG2 3.26Å; L187-V191 WeakPolarHBondContact O-CG2 3.18Å; L187-V191 PolarHBondContact O-N 3.49Å
188	W	97.4	Very high	93.4	Very high	51 Å²	51	58.2 Å²	58.2	19%	0.193	33%	0.332	C	S	.	.	H	α-helix	trans	-58.1	-46.6	175.6	-82.3	114.7	0	0	0	112.1	H104 V107 A108 L145 A149 F153 C184 A185 F186 A192	H104-W188 AromaticContact CE1-NE1 3.85Å; H104-W188 AromaticContact CG-NE1 3.75Å; H104-W188 AromaticContact ND1-CD1 3.8Å; H104-W188 AromaticContact ND1-NE1 3.03Å; H104-W188 PolarHBondContact ND1-NE1 2.97Å; V107-W188 HydrophobicContact CB-CZ2 4.49Å; V107-W188 HydrophobicContact CG1-CH2 4.41Å; V107-W188 HydrophobicContact CG1-CZ2 4.12Å; A108-W188 HydrophobicContact CB-CH2 3.77Å; A108-W188 HydrophobicContact CB-CZ2 4.21Å; L145-W188 HydrophobicContact CD1-CE3 4.42Å; L145-W188 HydrophobicContact CD1-CZ3 4.24Å; L145-W188 HydrophobicContact CD2-CZ3 3.93Å; L145-W188 HydrophobicContact CG-CZ3 4Å; A149-W188 HydrophobicContact CB-CH2 4.39Å; A149-W188 HydrophobicContact CB-CZ3 4.38Å; F153-W188 AromaticContact CE2-CZ2 3.95Å; F153-W188 HydrophobicContact CE2-CZ2 3.95Å; F153-W188 AromaticContact CZ-CE2 3.91Å; F153-W188 HydrophobicContact CZ-CZ2 4.28Å; F153-W188 AromaticContact CZ-NE1 3.55Å; C184-W188 PolarHBondContact O-N 3.5Å; A185-W188 PolarHBondContact O-N 2.9Å; F186-W188 PolarHBondContact O-N 3.15Å; W188-A192 WeakPolarHBondContact O-CB 3.35Å; W188-A192 PolarHBondContact O-N 2.97Å
189	V	96.8	Very high	93.3	Very high	95 Å²	95	55.9 Å²	55.9	58%	0.576	32%	0.32	S	S	*	.	H	α-helix	trans	-62.7	-49.9	177.8	173.1	0	0	0	0	110.6	A185 F186 L187 V191 A192 V193	A185-V189 WeakPolarHBondContact O-CG2 3.21Å; A185-V189 PolarHBondContact O-N 3.2Å; A185-V189 VanDerWaalsContact O-N 3.14Å; F186-V189 PolarHBondContact O-N 3.48Å; L187-V189 VanDerWaalsContact C-N 3.34Å; L187-V189 PolarHBondContact O-N 3.28Å; V189-V191 PolarHBondContact O-N 2.84Å; V189-A192 PolarHBondContact O-N 3.37Å; V189-V193 HydrophobicContact CG1-CG2 4.24Å; V189-V193 WeakPolarHBondContact O-CB 3.27Å; V189-V193 VanDerWaalsContact O-CG2 3.22Å; V189-V193 WeakPolarHBondContact O-CG2 3.45Å; V189-V193 PolarHBondContact O-N 3.48Å
190	V	93.9	Very high	93	Very high	59 Å²	59	55.9 Å²	55.9	36%	0.358	33%	0.332	S	S	.	.	H	α-helix	trans	-59.2	-49.5	-178.3	169.4	0	0	0	0	111.3	F186 L187 A194	F186-V190 HydrophobicContact CD1-CG2 4.23Å; F186-V190 HydrophobicContact CD2-CG2 4.15Å; F186-V190 HydrophobicContact CE1-CG2 3.8Å; F186-V190 HydrophobicContact CE2-CG2 3.7Å; F186-V190 HydrophobicContact CG-CG2 4.4Å; F186-V190 HydrophobicContact CZ-CG2 3.52Å; F186-V190 WeakPolarHBondContact O-CG2 3.36Å; F186-V190 PolarHBondContact O-N 3.11Å; L187-V190 PolarHBondContact O-N 3.39Å; V190-A194 VanDerWaalsContact O-CB 3.25Å; V190-A194 WeakPolarHBondContact O-CB 3.46Å; V190-A194 PolarHBondContact O-N 2.95Å
191	V	93.7	Very high	92.4	Very high	2 Å²	2	58.6 Å²	58.6	1%	0.012	35%	0.35	C	S	.	.	H	α-helix	trans	-68.2	-44.4	-178.4	-177.8	0	0	0	0	110.5	L145 Y152 L187 V189 V193 A194 M195	L145-V191 HydrophobicContact CD1-CB 4.5Å; L145-V191 HydrophobicContact CD1-CG1 3.99Å; Y152-V191 HydrophobicContact CD2-CG2 3.68Å; Y152-V191 HydrophobicContact CE2-CG2 3.92Å; L187-V191 WeakPolarHBondContact O-CB 3.36Å; L187-V191 VanDerWaalsContact O-CG2 3.26Å; L187-V191 WeakPolarHBondContact O-CG2 3.18Å; L187-V191 PolarHBondContact O-N 3.49Å; V189-V191 PolarHBondContact O-N 2.84Å; V191-V193 PolarHBondContact O-N 2.98Å; V191-A194 PolarHBondContact O-N 3.32Å; V191-M195 HydrophobicContact CG1-CG 4.21Å; V191-M195 VanDerWaalsContact O-CG 3.28Å; V191-M195 WeakPolarHBondContact O-CG 3.32Å; V191-M195 PolarHBondContact O-N 2.88Å
192	A	93.3	Very high	91.9	Very high	34 Å²	34	61 Å²	61	28%	0.281	36%	0.362	S	S	.	.	H	α-helix	trans	-61.6	-44.4	179.3	0	0	0	0	0	112.1	F141 L145 W188 V189 M195 A196	F141-A192 HydrophobicContact CZ-CB 4.42Å; L145-A192 HydrophobicContact CD1-CB 4.08Å; W188-A192 WeakPolarHBondContact O-CB 3.35Å; W188-A192 PolarHBondContact O-N 2.97Å; V189-A192 PolarHBondContact O-N 3.37Å; A192-M195 PolarHBondContact O-N 3.31Å; A192-A196 WeakPolarHBondContact O-CB 3.32Å; A192-A196 PolarHBondContact O-N 3.17Å
193	V	92	Very high	91.5	Very high	100 Å²	100	56.8 Å²	56.8	61%	0.606	34%	0.339	S	S	*	.	H	α-helix	trans	-63.3	-44	176.4	170.4	0	0	0	0	110.7	V189 V191 M195 A196	V189-V193 HydrophobicContact CG1-CG2 4.24Å; V189-V193 WeakPolarHBondContact O-CB 3.27Å; V189-V193 VanDerWaalsContact O-CG2 3.22Å; V189-V193 WeakPolarHBondContact O-CG2 3.45Å; V189-V193 PolarHBondContact O-N 3.48Å; V191-V193 PolarHBondContact O-N 2.98Å; V193-M195 VanDerWaalsContact C-N 3.28Å; V193-M195 PolarHBondContact O-N 2.93Å; V193-A196 WeakPolarHBondContact O-CB 3.24Å; V193-A196 PolarHBondContact O-N 2.9Å
194	A	88.8	Confident	91	Very high	55 Å²	55	56.3 Å²	56.3	46%	0.455	33%	0.333	S	S	.	.	H	α-helix	trans	-64.4	-32.2	178.6	0	0	0	0	0	112.7	V190 V191 P197	V190-A194 VanDerWaalsContact O-CB 3.25Å; V190-A194 WeakPolarHBondContact O-CB 3.46Å; V190-A194 PolarHBondContact O-N 2.95Å; V191-A194 PolarHBondContact O-N 3.32Å; A194-P197 WeakPolarHBondContact O-CD 3.27Å
195	M	89	Confident	90.5	Very high	19 Å²	19	58.4 Å²	58.4	9%	0.094	35%	0.345	C	S	.	.	H	α-helix	trans	-88.7	-14.1	177.7	-59.1	-44.3	121.6	0	0	114	F141 Y144 Y148 V191 A192 V193 P197 L198	F141-M195 HydrophobicContact CD2-CB 3.72Å; F141-M195 HydrophobicContact CE2-CB 3.79Å; Y144-M195 HydrophobicContact CD1-SD 4.45Å; Y144-M195 HydrophobicContact CG-SD 4.35Å; Y148-M195 HydrophobicContact CD2-CE 3.23Å; Y148-M195 HydrophobicContact CD2-SD 3.63Å; Y148-M195 HydrophobicContact CE2-CE 3.35Å; Y148-M195 HydrophobicContact CE2-SD 3.64Å; Y148-M195 HydrophobicContact CG-CE 4.1Å; V191-M195 HydrophobicContact CG1-CG 4.21Å; V191-M195 VanDerWaalsContact O-CG 3.28Å; V191-M195 WeakPolarHBondContact O-CG 3.32Å; V191-M195 PolarHBondContact O-N 2.88Å; A192-M195 PolarHBondContact O-N 3.31Å; V193-M195 VanDerWaalsContact C-N 3.28Å; V193-M195 PolarHBondContact O-N 2.93Å; M195-P197 VanDerWaalsContact C-N 3.33Å; M195-L198 VanDerWaalsContact O-CB 3.31Å; M195-L198 WeakPolarHBondContact O-CB 3.44Å; M195-L198 WeakPolarHBondContact O-CG 3.42Å; M195-L198 PolarHBondContact O-N 3.08Å; M195-L198 VanDerWaalsContact O-N 3.09Å
196	A	89.4	Confident	89.9	Confident	39 Å²	39	62.4 Å²	62.4	32%	0.322	36%	0.355	S	S	.	.	T	Hydrogen-bonded Turn	trans	-53.2	-34	-177.7	0	0	0	0	0	115.7	A192 V193 L198 L199	A192-A196 WeakPolarHBondContact O-CB 3.32Å; A192-A196 PolarHBondContact O-N 3.17Å; V193-A196 WeakPolarHBondContact O-CB 3.24Å; V193-A196 PolarHBondContact O-N 2.9Å; A196-L198 PolarHBondContact O-N 2.88Å; A196-L199 WeakPolarHBondContact O-CB 3.31Å; A196-L199 PolarHBondContact O-N 2.94Å
197	P	87.5	Confident	89.1	Confident	79 Å²	79	56.3 Å²	56.3	51%	0.513	33%	0.329	S	S	.	.	H	α-helix	trans	-57.1	-24.2	177.2	-27.7	36.8	0	0	0	114.5	A194 M195 L199 V200 S201	A194-P197 WeakPolarHBondContact O-CD 3.27Å; M195-P197 VanDerWaalsContact C-N 3.33Å; P197-L199 PolarHBondContact O-N 3.31Å; P197-V200 PolarHBondContact O-N 2.9Å; P197-S201 PolarHBondContact O-N 2.72Å; P197-S201 PolarHBondContact O-OG 2.94Å
198	L	85.6	Confident	88.1	Confident	33 Å²	33	61.9 Å²	61.9	17%	0.173	36%	0.359	C	S	.	.	H	α-helix	trans	-67.6	-23.1	176	-58.8	178.5	0	0	0	112.8	Y144 M195 A196	Y144-L198 HydrophobicContact CD2-CD1 3.68Å; Y144-L198 HydrophobicContact CE2-CD1 4.43Å; Y144-L198 HydrophobicContact CG-CD1 4.06Å; M195-L198 VanDerWaalsContact O-CB 3.31Å; M195-L198 WeakPolarHBondContact O-CB 3.44Å; M195-L198 WeakPolarHBondContact O-CG 3.42Å; M195-L198 PolarHBondContact O-N 3.08Å; M195-L198 VanDerWaalsContact O-N 3.09Å; A196-L198 PolarHBondContact O-N 2.88Å
199	L	89.3	Confident	87.2	Confident	62 Å²	62	68.2 Å²	68.2	33%	0.325	39%	0.39	S	S	.	.	H	α-helix	trans	-81.6	-20.4	179.1	-64.4	173.9	0	0	0	113.5	R137 L138 F141 A196 P197	R137-L199 WeakPolarHBondContact CD-O 3.31Å; R137-L199 PolarHBondContact NH1-O 3.43Å; L138-L199 HydrophobicContact CD2-CD2 3.88Å; F141-L199 HydrophobicContact CB-CD2 3.55Å; F141-L199 HydrophobicContact CB-CG 3.99Å; F141-L199 HydrophobicContact CD1-CD1 4.46Å; F141-L199 HydrophobicContact CD1-CD2 4.32Å; F141-L199 HydrophobicContact CD2-CD1 3.82Å; F141-L199 HydrophobicContact CD2-CD2 4.26Å; F141-L199 HydrophobicContact CD2-CG 3.85Å; F141-L199 HydrophobicContact CE2-CD1 4.03Å; F141-L199 HydrophobicContact CG-CD1 4.05Å; F141-L199 HydrophobicContact CG-CD2 3.79Å; F141-L199 HydrophobicContact CG-CG 3.92Å; F141-L199 HydrophobicContact CZ-CD1 4.44Å; A196-L199 WeakPolarHBondContact O-CB 3.31Å; A196-L199 PolarHBondContact O-N 2.94Å; P197-L199 PolarHBondContact O-N 3.31Å
200	V	87	Confident	86.6	Confident	114 Å²	114	66 Å²	66	69%	0.691	38%	0.377	S	S	*	.	H	α-helix	trans	-100	-36.4	-173.5	-174.7	0	0	0	0	111.6	R137 P197	R137-V200 PolarHBondContact NH1-O 3.22Å; P197-V200 PolarHBondContact O-N 2.9Å
201	S	81.6	Confident	86.3	Confident	58 Å²	58	64.3 Å²	64.3	41%	0.406	37%	0.367	S	S	.	.	S	Bend	trans	-71.7	144.8	-175.3	-55.8	0	0	0	0	111.9	R137 P197 Q203	R137-S201 WeakPolarHBondContact CD-O 3.14Å; R137-S201 PolarHBondContact NE-O 3.19Å; P197-S201 PolarHBondContact O-N 2.72Å; P197-S201 PolarHBondContact O-OG 2.94Å; S201-Q203 WeakPolarHBondContact O-CG 3.36Å; S201-Q203 PolarHBondContact O-N 3.05Å
202	Q	84.3	Confident	85.9	Confident	135 Å²	135	64.5 Å²	64.5	63%	0.631	37%	0.368	S	S	*	.			trans	-69.6	126.5	173	-173.1	174.7	-11.7	0	0	111.1	E133	E133-Q202 WeakPolarHBondContact OE1-CA 3.36Å
203	Q	87.1	Confident	85.6	Confident	13 Å²	13	63 Å²	63	6%	0.061	36%	0.355	C	S	.	.			trans	-122.9	-11.1	-171.5	-63.4	-59.7	-20.2	0	0	114.9	E133 C136 R137 S201 L214 Q215	E133-Q203 PolarHBondContact OE1-N 3.39Å; C136-Q203 WeakPolarHBondContact SG-CB 3.28Å; R137-Q203 HydrophobicContact CG-CB 4.29Å; R137-Q203 HydrophobicContact CG-CG 4.05Å; S201-Q203 WeakPolarHBondContact O-CG 3.36Å; S201-Q203 PolarHBondContact O-N 3.05Å; Q203-L214 VanDerWaalsContact O-CB 3.32Å; Q203-L214 WeakPolarHBondContact O-CB 3.36Å; Q203-L214 WeakPolarHBondContact O-CG 3.47Å; Q203-L214 PolarHBondContact O-N 2.99Å; Q203-Q215 HydrophobicContact CB-CB 4.5Å; Q203-Q215 HydrophobicContact CG-CB 4.49Å
204	T	86.6	Confident	85	Confident	23 Å²	23	58.5 Å²	58.5	14%	0.141	33%	0.328	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-94.8	139.1	169.9	57.4	0	0	0	0	111.5	E133 C136 V211 V212	E133-T204 WeakPolarHBondContact OE2-CA 3.07Å; E133-T204 WeakPolarHBondContact OE2-CB 3.44Å; E133-T204 WeakPolarHBondContact OE2-CG2 3.41Å; E133-T204 PolarHBondContact OE2-N 3.08Å; E133-T204 PolarHBondContact OE2-OG1 3.3Å; C136-T204 HydrophobicContact CB-CG2 3.79Å; T204-V211 HydrophobicContact CG2-CG1 4Å; T204-V212 WeakPolarHBondContact CA-O 3.48Å
205	V	86.3	Confident	84.5	Confident	44 Å²	44	56.1 Å²	56.1	27%	0.267	31%	0.307	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.2	138.2	173.5	177.9	0	0	0	0	108.7	L49 V212 L214	L49-V205 HydrophobicContact CD2-CB 4.43Å; L49-V205 HydrophobicContact CD2-CG1 3.73Å; V205-V212 PolarHBondContact N-O 3.44Å; V205-V212 PolarHBondContact O-N 3.42Å; V205-L214 HydrophobicContact CG2-CD1 3.72Å; V205-L214 HydrophobicContact CG2-CD2 4Å; V205-L214 HydrophobicContact CG2-CG 3.89Å
206	Q	85.4	Confident	83.8	Confident	139 Å²	139	55.2 Å²	55.2	65%	0.65	30%	0.303	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-83.4	128.5	170.4	-69.4	-70.5	9.6	0	0	109.3	T210 V211	Q206-T210 PolarHBondContact OE1-O 2.79Å; Q206-V211 VanDerWaalsContact NE2-CG2 3.31Å; Q206-V211 VanDerWaalsContact OE1-CG2 3.24Å
207	T	79.2	Confident	82.8	Confident	8 Å²	8	54 Å²	54	5%	0.049	29%	0.29	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.5	105.1	-174.5	-64.3	0	0	0	0	108.3	E53 H209 T210	E53-T207 HydrophobicContact CG-CG2 4.25Å; E53-T207 WeakPolarHBondContact OE1-CG2 3.29Å; T207-H209 PolarHBondContact O-N 3.24Å; T207-T210 PolarHBondContact N-O 3.33Å; T207-T210 PolarHBondContact O-N 2.87Å; T207-T210 PolarHBondContact O-OG1 2.93Å
208	N	76.4	Confident	81.6	Confident	138 Å²	138	54.1 Å²	54.1	74%	0.738	28%	0.28	S	S	*	.	T	Hydrogen-bonded Turn	trans	54	-95.1	-168.8	-56.9	-48.7	0	0	0	113	E53	E53-N208 PolarHBondContact OE1-ND2 3.33Å
209	H	78	Confident	80.7	Confident	183 Å²	183	53.2 Å²	53.2	85%	0.847	28%	0.275	S	S	*	.	T	Hydrogen-bonded Turn	trans	-122.7	8.8	179.6	-64.3	-37.7	0	0	0	113.2	T207	T207-H209 PolarHBondContact O-N 3.24Å
210	T	84.4	Confident	79.6	Confident	49 Å²	49	57.5 Å²	57.5	30%	0.301	29%	0.291	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.9	143	179.2	56.6	0	0	0	0	111.5	H128 Q206 T207	H128-T210 HydrophobicContact CB-CG2 4.29Å; Q206-T210 PolarHBondContact OE1-O 2.79Å; T207-T210 PolarHBondContact N-O 3.33Å; T207-T210 PolarHBondContact O-N 2.87Å; T207-T210 PolarHBondContact O-OG1 2.93Å
211	V	86.6	Confident	78.6	Confident	23 Å²	23	53.6 Å²	53.6	14%	0.139	27%	0.271	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-87.4	127.1	168.7	-179.3	0	0	0	0	107.1	H128 W129 T204 Q206	H128-V211 PolarHBondContact ND1-N 3.39Å; W129-V211 HydrophobicContact CB-CB 4.48Å; W129-V211 HydrophobicContact CB-CG1 4.23Å; W129-V211 WeakPolarHBondContact CB-O 3.48Å; W129-V211 PolarHBondContact N-O 3.24Å; T204-V211 HydrophobicContact CG2-CG1 4Å; Q206-V211 VanDerWaalsContact NE2-CG2 3.31Å; Q206-V211 VanDerWaalsContact OE1-CG2 3.24Å
212	V	86.8	Confident	78.1	Confident	7 Å²	7	53.1 Å²	53.1	4%	0.042	27%	0.267	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.4	133.9	174.8	-178.9	0	0	0	0	109.3	T204 V205	T204-V212 WeakPolarHBondContact CA-O 3.48Å; V205-V212 PolarHBondContact N-O 3.44Å; V205-V212 PolarHBondContact O-N 3.42Å
213	C	86.3	Confident	77.3	Confident	1 Å²	1	51.6 Å²	51.6	1%	0.007	26%	0.26	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-87.9	110	169.7	176.6	0	0	0	0	109.4	W129 C136 Q215 L216	W129-C213 HydrophobicContact CB-CB 4.19Å; W129-C213 HydrophobicContact CD2-CB 3.73Å; W129-C213 HydrophobicContact CE3-CB 4Å; W129-C213 HydrophobicContact CG-CB 3.8Å; C136-C213 VanDerWaalsContact CA-SG 3.5Å; C136-C213 HydrophobicContact CB-CB 3.84Å; C136-C213 WeakPolarHBondContact CB-SG 3.5Å; C136-C213 WeakPolarHBondContact SG-CA 3.4Å; C136-C213 WeakPolarHBondContact SG-CB 3.25Å; C136-C213 CovalentContact SG-SG 2.03Å; C136-C213 PolarHBondContact SG-SG 3.29Å; C213-Q215 PolarHBondContact O-N 2.62Å; C213-L216 HydrophobicContact CB-CD1 3.8Å; C213-L216 HydrophobicContact CB-CG 4.1Å; C213-L216 PolarHBondContact O-N 3.22Å
214	L	79.5	Confident	76.5	Confident	7 Å²	7	58.4 Å²	58.4	4%	0.037	29%	0.292	C	S	.	.	H	α-helix	trans	-57.2	-33.6	-178.5	-66.8	178.6	0	0	0	112	Q203 V205 L216 Y217 R218 E219	Q203-L214 VanDerWaalsContact O-CB 3.32Å; Q203-L214 WeakPolarHBondContact O-CB 3.36Å; Q203-L214 WeakPolarHBondContact O-CG 3.47Å; Q203-L214 PolarHBondContact O-N 2.99Å; V205-L214 HydrophobicContact CG2-CD1 3.72Å; V205-L214 HydrophobicContact CG2-CD2 4Å; V205-L214 HydrophobicContact CG2-CG 3.89Å; L214-L216 PolarHBondContact O-N 3.29Å; L214-Y217 PolarHBondContact O-N 2.97Å; L214-R218 HydrophobicContact CD2-CB 3.95Å; L214-R218 CarbonylContact O-C 3.11Å; L214-R218 WeakPolarHBondContact O-CA 3.41Å; L214-R218 PolarHBondContact O-N 3.24Å; L214-E219 PolarHBondContact O-N 3.45Å; L214-E219 VanDerWaalsContact O-N 3.15Å
215	Q	78.5	Confident	75.7	Confident	4 Å²	4	59.4 Å²	59.4	2%	0.019	30%	0.302	C	S	.	.	H	α-helix	trans	-74.1	-6	-173.8	-157.6	57.1	26.1	0	0	114.3	Q203 C213	Q203-Q215 HydrophobicContact CB-CB 4.5Å; Q203-Q215 HydrophobicContact CG-CB 4.49Å; C213-Q215 PolarHBondContact O-N 2.62Å
216	L	73.3	Confident	75	Confident	1 Å²	1	58.7 Å²	58.7	1%	0.005	30%	0.297	C	S	.	.	H	α-helix	trans	-77.9	-50.3	173.1	-74.5	168.2	0	0	0	112	R119 Y122 W129 T139 C213 L214	R119-L216 HydrophobicContact CG-CD2 3.67Å; R119-L216 PolarHBondContact NH1-O 3.07Å; Y122-L216 HydrophobicContact CD1-CD1 3.77Å; Y122-L216 HydrophobicContact CD2-CD1 3.37Å; Y122-L216 HydrophobicContact CE1-CD1 3.96Å; Y122-L216 HydrophobicContact CE2-CD1 3.56Å; Y122-L216 HydrophobicContact CG-CD1 3.46Å; Y122-L216 VanDerWaalsContact CG-CD1 3.46Å; W129-L216 HydrophobicContact CE3-CD1 3.81Å; W129-L216 HydrophobicContact CZ3-CD1 4.04Å; T139-L216 HydrophobicContact CG2-CD2 4.05Å; C213-L216 HydrophobicContact CB-CD1 3.8Å; C213-L216 HydrophobicContact CB-CG 4.1Å; C213-L216 PolarHBondContact O-N 3.22Å; L214-L216 PolarHBondContact O-N 3.29Å
217	Y	68.5	Low	74.4	Confident	12 Å²	12	55.5 Å²	55.5	5%	0.047	29%	0.286	C	S	.	.	H	α-helix	trans	-152.8	-1.5	-171.4	-52.5	-67.7	0	0	0	115.4	Y70 R119 Y122 H123 L214 N311 R312	Y70-Y217 VanDerWaalsContact CE2-OH 3.28Å; Y70-Y217 WeakPolarHBondContact CE2-OH 3.36Å; Y70-Y217 PolarHBondContact OH-OH 2.97Å; R119-Y217 VanDerWaalsContact NH1-CE1 3.34Å; R119-Y217 VanDerWaalsContact NH1-CZ 3.33Å; R119-Y217 PolarHBondContact NH1-OH 3.29Å; Y122-Y217 HydrophobicContact CD1-CE2 4.18Å; Y122-Y217 HydrophobicContact CE1-CD2 4.04Å; Y122-Y217 AromaticContact CE1-CE2 3.86Å; Y122-Y217 HydrophobicContact CE1-CE2 3.86Å; H123-Y217 AromaticContact CE1-CE2 3.85Å; H123-Y217 AromaticContact NE2-CE2 3.61Å; H123-Y217 AromaticContact NE2-CZ 3.57Å; H123-Y217 PolarHBondContact NE2-OH 2.98Å; L214-Y217 PolarHBondContact O-N 2.97Å; Y217-N311 VanDerWaalsContact C-ND2 3.29Å; Y217-N311 VanDerWaalsContact CA-ND2 3.35Å; Y217-N311 WeakPolarHBondContact CA-ND2 3.47Å; Y217-N311 PolarHBondContact O-ND2 3.48Å; Y217-R312 HydrophobicContact CD1-CB 4.14Å; Y217-R312 HydrophobicContact CD1-CG 3.59Å; Y217-R312 HydrophobicContact CD2-CG 4.24Å; Y217-R312 HydrophobicContact CE1-CB 4.08Å; Y217-R312 HydrophobicContact CE1-CG 3.82Å; Y217-R312 HydrophobicContact CE2-CG 4.43Å; Y217-R312 HydrophobicContact CG-CG 3.84Å
218	R	62.4	Low	74.1	Confident	83 Å²	83	58.4 Å²	58.4	31%	0.313	31%	0.307	S	S	.	.			trans	-128.6	40.3	-171.9	-68.1	-171.2	178.7	179.7	-0.1	112.7	L214	L214-R218 HydrophobicContact CD2-CB 3.95Å; L214-R218 CarbonylContact O-C 3.11Å; L214-R218 WeakPolarHBondContact O-CA 3.41Å; L214-R218 PolarHBondContact O-N 3.24Å
219	E	67.3	Low	74.2	Confident	14 Å²	14	52.4 Å²	52.4	7%	0.065	28%	0.275	C	S	.	.	P	Polyproline II helix	trans	-68.3	140.5	-178.2	-65.4	170.5	-143.4	0	0	112.7	Y144 L214 A221 Y283 R287	Y144-E219 WeakPolarHBondContact CE2-OE1 3.42Å; Y144-E219 VanDerWaalsContact CZ-OE1 3.23Å; Y144-E219 PolarHBondContact OH-OE1 2.87Å; Y144-E219 PolarHBondContact OH-OE2 2.91Å; L214-E219 PolarHBondContact O-N 3.45Å; L214-E219 VanDerWaalsContact O-N 3.15Å; E219-A221 PolarHBondContact O-N 3.17Å; E219-Y283 PolarHBondContact OE1-OH 3.27Å; E219-R287 VanDerWaalsContact CB-CZ 3.49Å; E219-R287 PolarHBondContact O-NH1 3.46Å; E219-R287 IonicContact OE2-CZ 2.69Å; E219-R287 IonicContact OE2-NE 3.72Å; E219-R287 PolarHBondContact OE2-NE 3.24Å; E219-R287 IonicContact OE2-NH2 2.74Å; E219-R287 PolarHBondContact OE2-NH2 3.28Å
220	K	65.4	Low	74.1	Confident	151 Å²	151	45.6 Å²	45.6	66%	0.657	25%	0.251	S	S	*	.	P	Polyproline II helix	trans	-56.9	135	-179.4	-64.7	-179.8	-179.2	176	0	111.7	R287	K220-R287 PolarHBondContact O-NH2 3.42Å
221	A	66.4	Low	73.8	Confident	32 Å²	32	47.8 Å²	47.8	26%	0.264	26%	0.264	S	S	.	.	P	Polyproline II helix	trans	-81.1	122	173.1	0	0	0	0	0	109.8	E219 V291 Y294	E219-A221 PolarHBondContact O-N 3.17Å; A221-V291 HydrophobicContact CB-CB 4.39Å; A221-V291 HydrophobicContact CB-CG1 4.19Å; A221-V291 HydrophobicContact CB-CG2 4.13Å; A221-Y294 HydrophobicContact CB-CD1 3.8Å; A221-Y294 HydrophobicContact CB-CG 4.2Å
222	S	71.4	Confident	73.6	Confident	48 Å²	48	47.4 Å²	47.4	34%	0.336	26%	0.263	S	S	.	.			trans	-140.2	143.7	175.7	173.7	0	0	0	0	110.4	H224 A225 L226	S222-H224 VanDerWaalsContact C-N 3.29Å; S222-H224 PolarHBondContact O-N 3.4Å; S222-H224 PolarHBondContact OG-N 3.25Å; S222-A225 WeakPolarHBondContact O-CB 3.44Å; S222-A225 PolarHBondContact O-N 2.85Å; S222-L226 PolarHBondContact O-N 3.05Å
223	H	68.6	Low	73.7	Confident	104 Å²	104	48.1 Å²	48.1	48%	0.481	27%	0.265	S	S	.	.	H	α-helix	trans	-60.8	-40.8	177.1	-172.2	-91.2	0	0	0	111.5	A225 L226 V227	H223-A225 VanDerWaalsContact C-N 3.31Å; H223-A225 PolarHBondContact O-N 3.23Å; H223-L226 PolarHBondContact O-N 3.4Å; H223-V227 WeakPolarHBondContact O-CG2 3.44Å; H223-V227 PolarHBondContact O-N 2.95Å
224	H	70.1	Confident	73.7	Confident	155 Å²	155	51.6 Å²	51.6	72%	0.718	29%	0.287	S	S	*	.	H	α-helix	trans	-63.9	-38.4	176.9	-63.6	-69.9	0	0	0	111.8	S222 S228	S222-H224 VanDerWaalsContact C-N 3.29Å; S222-H224 PolarHBondContact O-N 3.4Å; S222-H224 PolarHBondContact OG-N 3.25Å; H224-S228 VanDerWaalsContact O-CB 3.25Å; H224-S228 WeakPolarHBondContact O-CB 3.31Å; H224-S228 PolarHBondContact O-N 3.5Å
225	A	69	Low	74.2	Confident	44 Å²	44	57.7 Å²	57.7	36%	0.364	31%	0.313	S	S	.	.	H	α-helix	trans	-66.5	-40.6	176	0	0	0	0	0	111.7	S222 H223 L229	S222-A225 WeakPolarHBondContact O-CB 3.44Å; S222-A225 PolarHBondContact O-N 2.85Å; H223-A225 VanDerWaalsContact C-N 3.31Å; H223-A225 PolarHBondContact O-N 3.23Å; A225-L229 WeakPolarHBondContact O-CB 3.24Å; A225-L229 PolarHBondContact O-N 2.97Å
226	L	71.9	Confident	74.7	Confident	30 Å²	30	57.5 Å²	57.5	16%	0.157	31%	0.312	C	S	.	.	H	α-helix	trans	-63.9	-48	177.1	-177.6	64.8	0	0	0	112.1	S222 H223 L229 A230 V291 L292	S222-L226 PolarHBondContact O-N 3.05Å; H223-L226 PolarHBondContact O-N 3.4Å; L226-L229 PolarHBondContact O-N 3.35Å; L226-A230 WeakPolarHBondContact O-CB 3.33Å; L226-A230 PolarHBondContact O-N 3.07Å; L226-V291 HydrophobicContact CB-CG1 4.01Å; L226-V291 HydrophobicContact CD1-CB 4.27Å; L226-V291 HydrophobicContact CD1-CG1 4.5Å; L226-V291 HydrophobicContact CD2-CG1 4.09Å; L226-V291 HydrophobicContact CG-CG1 4.44Å; L226-L292 HydrophobicContact CD2-CD2 4.33Å
227	V	71.4	Confident	75.5	Confident	71 Å²	71	60.6 Å²	60.6	43%	0.43	33%	0.326	S	S	.	.	H	α-helix	trans	-63.3	-44.5	178.8	174.1	0	0	0	0	110.3	H223 L229 A230 V231	H223-V227 WeakPolarHBondContact O-CG2 3.44Å; H223-V227 PolarHBondContact O-N 2.95Å; V227-L229 PolarHBondContact O-N 3.29Å; V227-A230 PolarHBondContact O-N 3.5Å; V227-V231 HydrophobicContact CG1-CG2 4.35Å; V227-V231 WeakPolarHBondContact O-CB 3.44Å; V227-V231 VanDerWaalsContact O-CG2 3.28Å; V227-V231 WeakPolarHBondContact O-CG2 3.28Å; V227-V231 PolarHBondContact O-N 3.08Å
228	S	74.4	Confident	76.5	Confident	70 Å²	70	63.6 Å²	63.6	49%	0.49	35%	0.345	S	S	.	.	H	α-helix	trans	-62.6	-43	177.7	-169.8	0	0	0	0	112.1	H224 A232	H224-S228 VanDerWaalsContact O-CB 3.25Å; H224-S228 WeakPolarHBondContact O-CB 3.31Å; H224-S228 PolarHBondContact O-N 3.5Å; S228-A232 WeakPolarHBondContact O-CB 3.34Å; S228-A232 PolarHBondContact O-N 3.19Å
229	L	77	Confident	77.9	Confident	11 Å²	11	61.5 Å²	61.5	6%	0.058	34%	0.342	C	S	.	.	H	α-helix	trans	-62.9	-45.1	177.2	179.9	72.1	0	0	0	111.5	Y148 A225 L226 V227 F233 H284 R287	Y148-L229 WeakPolarHBondContact OH-CD1 3.32Å; A225-L229 WeakPolarHBondContact O-CB 3.24Å; A225-L229 PolarHBondContact O-N 2.97Å; L226-L229 PolarHBondContact O-N 3.35Å; V227-L229 PolarHBondContact O-N 3.29Å; L229-F233 WeakPolarHBondContact O-CB 3.19Å; L229-F233 PolarHBondContact O-N 3.3Å; L229-F233 VanDerWaalsContact O-N 3.1Å; L229-H284 VanDerWaalsContact CD1-CE1 3.5Å; L229-H284 WeakPolarHBondContact CD1-CE1 3.3Å; L229-H284 WeakPolarHBondContact CD1-ND1 3.36Å; L229-R287 HydrophobicContact CD2-CB 3.77Å; L229-R287 HydrophobicContact CD2-CG 3.35Å
230	A	77.2	Confident	79	Confident	41 Å²	41	60.9 Å²	60.9	34%	0.339	34%	0.339	S	S	.	.	H	α-helix	trans	-62.9	-50.5	178.2	0	0	0	0	0	110.7	L226 V227 A232 F233 T234	L226-A230 WeakPolarHBondContact O-CB 3.33Å; L226-A230 PolarHBondContact O-N 3.07Å; V227-A230 PolarHBondContact O-N 3.5Å; A230-A232 PolarHBondContact O-N 2.87Å; A230-F233 PolarHBondContact O-N 3.26Å; A230-T234 WeakPolarHBondContact O-CB 3.33Å; A230-T234 PolarHBondContact O-N 3.34Å; A230-T234 PolarHBondContact O-OG1 3.42Å
231	V	77.1	Confident	80.1	Confident	95 Å²	95	55.9 Å²	55.9	58%	0.576	32%	0.321	S	S	*	.	H	α-helix	trans	-61.5	-45.3	179.4	172.6	0	0	0	0	111.3	V227 F233 F235	V227-V231 HydrophobicContact CG1-CG2 4.35Å; V227-V231 WeakPolarHBondContact O-CB 3.44Å; V227-V231 VanDerWaalsContact O-CG2 3.28Å; V227-V231 WeakPolarHBondContact O-CG2 3.28Å; V227-V231 PolarHBondContact O-N 3.08Å; V231-F233 VanDerWaalsContact C-N 3.27Å; V231-F233 PolarHBondContact O-N 3.39Å; V231-F235 PolarHBondContact O-N 2.9Å
232	A	83.6	Confident	81.3	Confident	14 Å²	14	57.5 Å²	57.5	12%	0.116	33%	0.328	C	S	.	.	H	α-helix	trans	-62.7	-33.6	-178.5	0	0	0	0	0	112.7	Y148 Y152 S228 A230 P236	Y148-A232 HydrophobicContact CD1-CB 4.06Å; Y148-A232 HydrophobicContact CE1-CB 3.49Å; Y148-A232 VanDerWaalsContact CE1-CB 3.49Å; Y152-A232 PolarHBondContact OH-O 3.38Å; Y152-A232 VanDerWaalsContact OH-O 3.14Å; S228-A232 WeakPolarHBondContact O-CB 3.34Å; S228-A232 PolarHBondContact O-N 3.19Å; A230-A232 PolarHBondContact O-N 2.87Å; A232-P236 WeakPolarHBondContact O-CD 3.36Å; A232-P236 WeakPolarHBondContact O-CG 3.4Å
233	F	87.3	Confident	82.2	Confident	22 Å²	22	55.8 Å²	55.8	10%	0.096	32%	0.316	C	S	.	.	H	α-helix	trans	-90.1	-41.9	179.5	-179.7	-108.7	0	0	0	114.1	I151 L229 A230 V231 F235 P236 F237 F276 F280 V281 H284	I151-F233 HydrophobicContact CD1-CD2 4.06Å; L229-F233 WeakPolarHBondContact O-CB 3.19Å; L229-F233 PolarHBondContact O-N 3.3Å; L229-F233 VanDerWaalsContact O-N 3.1Å; A230-F233 PolarHBondContact O-N 3.26Å; V231-F233 VanDerWaalsContact C-N 3.27Å; V231-F233 PolarHBondContact O-N 3.39Å; F233-F235 PolarHBondContact O-N 2.81Å; F233-P236 VanDerWaalsContact O-CD 3.23Å; F233-P236 WeakPolarHBondContact O-CD 3.35Å; F233-P236 WeakPolarHBondContact O-CG 3.47Å; F233-F237 HydrophobicContact CE1-CB 4.22Å; F233-F237 HydrophobicContact CE1-CD2 4.43Å; F233-F237 HydrophobicContact CE1-CG 4.3Å; F233-F237 HydrophobicContact CZ-CB 4.19Å; F233-F237 HydrophobicContact CZ-CD2 4.02Å; F233-F237 HydrophobicContact CZ-CG 4.26Å; F233-F237 VanDerWaalsContact O-CB 3.27Å; F233-F237 WeakPolarHBondContact O-CB 3.38Å; F233-F237 PolarHBondContact O-N 2.63Å; F233-F237 VanDerWaalsContact O-N 3.07Å; F233-F276 HydrophobicContact CE2-CD1 4.08Å; F233-F276 HydrophobicContact CE2-CE1 4.31Å; F233-F280 HydrophobicContact CE2-CB 3.77Å; F233-F280 HydrophobicContact CZ-CB 4.5Å; F233-V281 HydrophobicContact CE1-CG2 4.22Å; F233-V281 HydrophobicContact CZ-CB 4.47Å; F233-V281 HydrophobicContact CZ-CG2 3.63Å; F233-H284 HydrophobicContact CD1-CB 4.04Å; F233-H284 AromaticContact CD1-CD2 3.92Å; F233-H284 AromaticContact CD1-CG 3.94Å; F233-H284 AromaticContact CD2-CD2 3.08Å; F233-H284 WeakPolarHBondContact CD2-CD2 3.47Å; F233-H284 AromaticContact CD2-CE1 3.98Å; F233-H284 AromaticContact CD2-CG 3.85Å; F233-H284 AromaticContact CD2-NE2 3.2Å; F233-H284 WeakPolarHBondContact CD2-NE2 3.39Å; F233-H284 HydrophobicContact CE1-CB 4.37Å; F233-H284 AromaticContact CE2-CD2 3.45Å; F233-H284 VanDerWaalsContact CE2-CD2 3.45Å; F233-H284 WeakPolarHBondContact CE2-CD2 3.38Å; F233-H284 AromaticContact CE2-NE2 3.89Å; F233-H284 HydrophobicContact CG-CB 4.22Å; F233-H284 AromaticContact CG-CD2 3.35Å; F233-H284 WeakPolarHBondContact CG-CD2 3.25Å; F233-H284 AromaticContact CG-CG 3.6Å; F233-H284 AromaticContact CG-ND1 3.99Å; F233-H284 AromaticContact CG-NE2 3.63Å
234	T	87.1	Confident	83	Confident	74 Å²	74	51 Å²	51	45%	0.454	29%	0.294	S	S	.	.	H	α-helix	trans	-64.6	-41.9	-173.9	-61	0	0	0	0	111.8	A230 F237 V238	A230-T234 WeakPolarHBondContact O-CB 3.33Å; A230-T234 PolarHBondContact O-N 3.34Å; A230-T234 PolarHBondContact O-OG1 3.42Å; T234-F237 PolarHBondContact O-N 3.07Å; T234-V238 HydrophobicContact CG2-CG2 4.03Å; T234-V238 WeakPolarHBondContact O-CB 3.4Å; T234-V238 VanDerWaalsContact O-CG2 3.27Å; T234-V238 WeakPolarHBondContact O-CG2 3.31Å; T234-V238 PolarHBondContact O-N 2.97Å
235	F	89.5	Confident	84	Confident	136 Å²	136	48.9 Å²	48.9	60%	0.596	29%	0.287	S	S	*	.	H	α-helix	trans	-58.4	-55.2	178.7	173.7	-98.8	0	0	0	113.6	Y152 V231 F233 F237 T239	Y152-F235 HydrophobicContact CE1-CD1 4.44Å; V231-F235 PolarHBondContact O-N 2.9Å; F233-F235 PolarHBondContact O-N 2.81Å; F235-F237 PolarHBondContact O-N 3.4Å; F235-T239 WeakPolarHBondContact O-CB 3.33Å; F235-T239 PolarHBondContact O-N 3.24Å; F235-T239 PolarHBondContact O-OG1 3.19Å
236	P	90.4	Very high	85	Confident	0 Å²	0	50.3 Å²	50.3	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-66.2	-35.8	178	21.7	-29.6	0	0	0	112.6	I151 Y152 T155 A232 F233 T239 T240	I151-P236 HydrophobicContact CG2-CB 3.5Å; I151-P236 VanDerWaalsContact CG2-CB 3.5Å; I151-P236 HydrophobicContact CG2-CG 3.31Å; Y152-P236 HydrophobicContact CD1-CB 4.21Å; Y152-P236 HydrophobicContact CD1-CG 4.32Å; Y152-P236 HydrophobicContact CE1-CB 4.22Å; Y152-P236 HydrophobicContact CE1-CG 3.91Å; T155-P236 HydrophobicContact CG2-CB 4.33Å; T155-P236 WeakPolarHBondContact OG1-CB 3.07Å; T155-P236 PolarHBondContact OG1-O 3.32Å; A232-P236 WeakPolarHBondContact O-CD 3.36Å; A232-P236 WeakPolarHBondContact O-CG 3.4Å; F233-P236 VanDerWaalsContact O-CD 3.23Å; F233-P236 WeakPolarHBondContact O-CD 3.35Å; F233-P236 WeakPolarHBondContact O-CG 3.47Å; P236-T239 PolarHBondContact O-N 3.02Å; P236-T240 WeakPolarHBondContact O-CB 3.35Å; P236-T240 PolarHBondContact O-N 3.05Å; P236-T240 PolarHBondContact O-OG1 3.15Å
237	F	88.9	Confident	85.7	Confident	65 Å²	65	48.9 Å²	48.9	29%	0.285	28%	0.28	S	S	.	.	H	α-helix	trans	-61.1	-52.5	176.2	179.7	-101.7	0	0	0	112.1	F233 T234 F235 T239 T240 V241 F276 V281	F233-F237 HydrophobicContact CE1-CB 4.22Å; F233-F237 HydrophobicContact CE1-CD2 4.43Å; F233-F237 HydrophobicContact CE1-CG 4.3Å; F233-F237 HydrophobicContact CZ-CB 4.19Å; F233-F237 HydrophobicContact CZ-CD2 4.02Å; F233-F237 HydrophobicContact CZ-CG 4.26Å; F233-F237 VanDerWaalsContact O-CB 3.27Å; F233-F237 WeakPolarHBondContact O-CB 3.38Å; F233-F237 PolarHBondContact O-N 2.63Å; F233-F237 VanDerWaalsContact O-N 3.07Å; T234-F237 PolarHBondContact O-N 3.07Å; F235-F237 PolarHBondContact O-N 3.4Å; F237-T239 VanDerWaalsContact C-N 3.33Å; F237-T239 PolarHBondContact O-N 3.37Å; F237-T240 PolarHBondContact O-N 2.98Å; F237-V241 HydrophobicContact CD1-CG2 4.45Å; F237-V241 HydrophobicContact CE1-CG2 4.09Å; F237-V241 HydrophobicContact CE2-CG2 4.16Å; F237-V241 HydrophobicContact CZ-CG2 3.93Å; F237-V241 WeakPolarHBondContact O-CG2 3.5Å; F237-V241 PolarHBondContact O-N 2.56Å; F237-F276 HydrophobicContact CD2-CD1 4.28Å; F237-V281 HydrophobicContact CE2-CG2 4.2Å
238	V	90.6	Very high	86.4	Confident	76 Å²	76	48.4 Å²	48.4	46%	0.461	28%	0.275	S	S	.	.	H	α-helix	trans	-60	-45.2	178.1	171.3	0	0	0	0	110.4	T234 T240 V241 T242	T234-V238 HydrophobicContact CG2-CG2 4.03Å; T234-V238 WeakPolarHBondContact O-CB 3.4Å; T234-V238 VanDerWaalsContact O-CG2 3.27Å; T234-V238 WeakPolarHBondContact O-CG2 3.31Å; T234-V238 PolarHBondContact O-N 2.97Å; V238-T240 PolarHBondContact O-N 3.27Å; V238-V241 PolarHBondContact O-N 2.66Å; V238-T242 WeakPolarHBondContact O-CB 3.23Å; V238-T242 PolarHBondContact O-N 2.94Å; V238-T242 PolarHBondContact O-OG1 3Å
239	T	91.3	Very high	87.1	Confident	39 Å²	39	52.7 Å²	52.7	24%	0.239	28%	0.28	C	S	.	.	H	α-helix	trans	-57.6	-49.2	178.1	-58.8	0	0	0	0	111.5	T155 F235 P236 F237 T242 C243	T155-T239 HydrophobicContact CG2-CG2 3.65Å; F235-T239 WeakPolarHBondContact O-CB 3.33Å; F235-T239 PolarHBondContact O-N 3.24Å; F235-T239 PolarHBondContact O-OG1 3.19Å; P236-T239 PolarHBondContact O-N 3.02Å; F237-T239 VanDerWaalsContact C-N 3.33Å; F237-T239 PolarHBondContact O-N 3.37Å; T239-T242 PolarHBondContact O-N 2.8Å; T239-C243 WeakPolarHBondContact O-CB 3.38Å; T239-C243 PolarHBondContact O-N 3.28Å; T239-C243 PolarHBondContact O-SG 3.06Å
240	T	89.9	Confident	87.5	Confident	1 Å²	1	52.5 Å²	52.5	1%	0.006	28%	0.28	C	S	.	.	H	α-helix	trans	-60.2	-47.5	178.6	-62.5	0	0	0	0	111.5	T155 P236 F237 V238 C243 Y244 V272 F276	T155-T240 PolarHBondContact OG1-OG1 3.39Å; P236-T240 WeakPolarHBondContact O-CB 3.35Å; P236-T240 PolarHBondContact O-N 3.05Å; P236-T240 PolarHBondContact O-OG1 3.15Å; F237-T240 PolarHBondContact O-N 2.98Å; V238-T240 PolarHBondContact O-N 3.27Å; T240-C243 PolarHBondContact O-N 3.41Å; T240-Y244 HydrophobicContact CG2-CD2 3.71Å; T240-Y244 HydrophobicContact CG2-CE2 3.35Å; T240-Y244 WeakPolarHBondContact O-CB 3.34Å; T240-Y244 VanDerWaalsContact O-CD2 3.31Å; T240-Y244 WeakPolarHBondContact O-CD2 3.29Å; T240-Y244 VanDerWaalsContact O-CG 3.25Å; T240-Y244 PolarHBondContact O-N 3.04Å; T240-V272 HydrophobicContact CG2-CG1 3.97Å; T240-F276 HydrophobicContact CG2-CD2 4.17Å; T240-F276 HydrophobicContact CG2-CE2 3.92Å
241	V	89.3	Confident	87.8	Confident	45 Å²	45	51.2 Å²	51.2	27%	0.273	27%	0.267	S	S	.	.	H	α-helix	trans	-60.7	-48.8	178.3	171.5	0	0	0	0	110.9	F237 V238 C243 Y244 L245	F237-V241 HydrophobicContact CD1-CG2 4.45Å; F237-V241 HydrophobicContact CE1-CG2 4.09Å; F237-V241 HydrophobicContact CE2-CG2 4.16Å; F237-V241 HydrophobicContact CZ-CG2 3.93Å; F237-V241 WeakPolarHBondContact O-CG2 3.5Å; F237-V241 PolarHBondContact O-N 2.56Å; V238-V241 PolarHBondContact O-N 2.66Å; V241-C243 PolarHBondContact O-N 3.37Å; V241-Y244 PolarHBondContact O-N 2.89Å; V241-L245 HydrophobicContact CG1-CD1 3.94Å; V241-L245 HydrophobicContact CG1-CG 4.28Å; V241-L245 WeakPolarHBondContact O-CG 3.19Å; V241-L245 PolarHBondContact O-N 3.15Å
242	T	90.9	Very high	88.1	Confident	67 Å²	67	56.7 Å²	56.7	41%	0.411	28%	0.277	S	S	.	.	H	α-helix	trans	-61.9	-45.9	178.9	-60.1	0	0	0	0	111.8	V238 T239 Y244 L245 L246	V238-T242 WeakPolarHBondContact O-CB 3.23Å; V238-T242 PolarHBondContact O-N 2.94Å; V238-T242 PolarHBondContact O-OG1 3Å; T239-T242 PolarHBondContact O-N 2.8Å; T242-Y244 PolarHBondContact O-N 2.92Å; T242-L245 PolarHBondContact O-N 3.2Å; T242-L246 HydrophobicContact CG2-CD1 4.01Å; T242-L246 HydrophobicContact CG2-CG 4.4Å; T242-L246 VanDerWaalsContact O-CG 3.3Å; T242-L246 WeakPolarHBondContact O-CG 3.3Å; T242-L246 PolarHBondContact O-N 3.47Å
243	C	90.1	Very high	88.1	Confident	12 Å²	12	62 Å²	62	8%	0.081	30%	0.3	C	S	.	.	H	α-helix	trans	-53.2	-44.3	174.9	-78.4	0	0	0	0	111.2	F162 T239 T240 V241 L246 I247	F162-C243 HydrophobicContact CB-CB 4.03Å; F162-C243 HydrophobicContact CG-CB 4.42Å; T239-C243 WeakPolarHBondContact O-CB 3.38Å; T239-C243 PolarHBondContact O-N 3.28Å; T239-C243 PolarHBondContact O-SG 3.06Å; T240-C243 PolarHBondContact O-N 3.41Å; V241-C243 PolarHBondContact O-N 3.37Å; C243-L246 PolarHBondContact O-N 2.81Å; C243-I247 WeakPolarHBondContact O-CG1 3.18Å; C243-I247 PolarHBondContact O-N 3.25Å
244	Y	86.8	Confident	87.2	Confident	4 Å²	4	63.7 Å²	63.7	2%	0.016	32%	0.324	C	S	.	.	H	α-helix	trans	-75	-38	-177.4	-65.9	-22	0	0	0	114.1	S158 T240 V241 T242 L246 I247 I248 I269 V272 L273	S158-Y244 VanDerWaalsContact OG-CZ 3.24Å; S158-Y244 PolarHBondContact OG-OH 3.06Å; T240-Y244 HydrophobicContact CG2-CD2 3.71Å; T240-Y244 HydrophobicContact CG2-CE2 3.35Å; T240-Y244 WeakPolarHBondContact O-CB 3.34Å; T240-Y244 VanDerWaalsContact O-CD2 3.31Å; T240-Y244 WeakPolarHBondContact O-CD2 3.29Å; T240-Y244 VanDerWaalsContact O-CG 3.25Å; T240-Y244 PolarHBondContact O-N 3.04Å; V241-Y244 PolarHBondContact O-N 2.89Å; T242-Y244 PolarHBondContact O-N 2.92Å; Y244-L246 VanDerWaalsContact C-N 3.29Å; Y244-L246 PolarHBondContact O-N 2.93Å; Y244-I247 HydrophobicContact CD1-CD1 3.93Å; Y244-I247 HydrophobicContact CE1-CD1 4.36Å; Y244-I247 PolarHBondContact O-N 3.19Å; Y244-I248 WeakPolarHBondContact O-CB 3.45Å; Y244-I248 VanDerWaalsContact O-CG1 3.26Å; Y244-I248 WeakPolarHBondContact O-CG1 3.03Å; Y244-I248 PolarHBondContact O-N 3.34Å; Y244-I269 HydrophobicContact CD1-CB 4.29Å; Y244-I269 HydrophobicContact CD1-CD1 4.06Å; Y244-I269 HydrophobicContact CD1-CG1 3.48Å; Y244-I269 VanDerWaalsContact CD1-CG1 3.48Å; Y244-I269 HydrophobicContact CD1-CG2 4.18Å; Y244-I269 HydrophobicContact CD2-CB 4.43Å; Y244-I269 HydrophobicContact CD2-CG1 4.47Å; Y244-I269 HydrophobicContact CD2-CG2 3.75Å; Y244-I269 HydrophobicContact CE1-CB 4.26Å; Y244-I269 HydrophobicContact CE1-CD1 4.48Å; Y244-I269 HydrophobicContact CE1-CG1 3.51Å; Y244-I269 HydrophobicContact CE2-CB 4.42Å; Y244-I269 HydrophobicContact CE2-CG2 4.13Å; Y244-I269 HydrophobicContact CG-CB 4.31Å; Y244-I269 HydrophobicContact CG-CD1 4.46Å; Y244-I269 HydrophobicContact CG-CG1 3.93Å; Y244-I269 HydrophobicContact CG-CG2 3.71Å; Y244-V272 HydrophobicContact CE2-CB 4.02Å; Y244-V272 HydrophobicContact CE2-CG1 3.84Å; Y244-V272 WeakPolarHBondContact OH-CB 3.06Å; Y244-V272 WeakPolarHBondContact OH-CG1 3.41Å; Y244-V272 VanDerWaalsContact OH-CG2 3.29Å; Y244-V272 WeakPolarHBondContact OH-CG2 3.48Å; Y244-L273 HydrophobicContact CD2-CD1 4.04Å; Y244-L273 HydrophobicContact CD2-CD2 3.82Å; Y244-L273 HydrophobicContact CD2-CG 3.72Å; Y244-L273 HydrophobicContact CE2-CD2 4.21Å; Y244-L273 HydrophobicContact CE2-CG 3.92Å
245	L	89.5	Confident	86.4	Confident	109 Å²	109	64.1 Å²	64.1	57%	0.571	32%	0.323	S	S	*	.	H	α-helix	trans	-59.4	-42.8	171.7	-69.7	175.8	0	0	0	111.4	V241 T242 I248 R249	V241-L245 HydrophobicContact CG1-CD1 3.94Å; V241-L245 HydrophobicContact CG1-CG 4.28Å; V241-L245 WeakPolarHBondContact O-CG 3.19Å; V241-L245 PolarHBondContact O-N 3.15Å; T242-L245 PolarHBondContact O-N 3.2Å; L245-I248 PolarHBondContact O-N 2.71Å; L245-R249 WeakPolarHBondContact O-CB 3.38Å; L245-R249 PolarHBondContact O-N 3.05Å
246	L	90.4	Very high	85.5	Confident	74 Å²	74	69.9 Å²	69.9	39%	0.387	34%	0.34	S	S	.	.	H	α-helix	trans	-68.6	-39.3	178	-66.2	175.5	0	0	0	112.4	F162 T242 C243 Y244 R249 S250	F162-L246 HydrophobicContact CD2-CB 4.05Å; F162-L246 HydrophobicContact CD2-CD1 4.42Å; F162-L246 HydrophobicContact CE2-CB 3.66Å; F162-L246 HydrophobicContact CE2-CD1 3.58Å; F162-L246 HydrophobicContact CE2-CG 4.28Å; F162-L246 HydrophobicContact CZ-CD1 4.01Å; T242-L246 HydrophobicContact CG2-CD1 4.01Å; T242-L246 HydrophobicContact CG2-CG 4.4Å; T242-L246 VanDerWaalsContact O-CG 3.3Å; T242-L246 WeakPolarHBondContact O-CG 3.3Å; T242-L246 PolarHBondContact O-N 3.47Å; C243-L246 PolarHBondContact O-N 2.81Å; Y244-L246 VanDerWaalsContact C-N 3.29Å; Y244-L246 PolarHBondContact O-N 2.93Å; L246-R249 PolarHBondContact O-N 3.37Å; L246-S250 WeakPolarHBondContact O-CB 3.32Å; L246-S250 PolarHBondContact O-N 3.37Å
247	I	87.3	Confident	84.6	Confident	0 Å²	0	71.6 Å²	71.6	0%	0	35%	0.351	C	S	.	.	H	α-helix	trans	-60.9	-48.9	172.8	-68.8	167.4	0	0	0	110.1	R161 F162 I165 V166 C243 Y244 R249 S250 L251 I269	R161-I247 HydrophobicContact CB-CD1 4.25Å; F162-I247 HydrophobicContact CB-CD1 4.04Å; F162-I247 HydrophobicContact CB-CG1 4.23Å; F162-I247 HydrophobicContact CD2-CG1 4.26Å; I165-I247 HydrophobicContact CD1-CG2 3.9Å; I165-I247 HydrophobicContact CG2-CG2 4.38Å; V166-I247 HydrophobicContact CG2-CG1 4.08Å; C243-I247 WeakPolarHBondContact O-CG1 3.18Å; C243-I247 PolarHBondContact O-N 3.25Å; Y244-I247 HydrophobicContact CD1-CD1 3.93Å; Y244-I247 HydrophobicContact CE1-CD1 4.36Å; Y244-I247 PolarHBondContact O-N 3.19Å; I247-R249 VanDerWaalsContact C-N 3.31Å; I247-R249 PolarHBondContact O-N 2.87Å; I247-S250 PolarHBondContact O-N 3.12Å; I247-L251 HydrophobicContact CG2-CD1 3.73Å; I247-L251 HydrophobicContact CG2-CG 4.13Å; I247-L251 WeakPolarHBondContact O-CB 3.48Å; I247-L251 WeakPolarHBondContact O-CG 3.26Å; I247-L251 PolarHBondContact O-N 3.28Å; I247-I269 HydrophobicContact CB-CD1 4.19Å; I247-I269 HydrophobicContact CD1-CD1 4.38Å; I247-I269 HydrophobicContact CG2-CD1 3.73Å
248	I	86.3	Confident	84.1	Confident	61 Å²	61	75.4 Å²	75.4	31%	0.313	37%	0.369	S	S	.	.	H	α-helix	trans	-58.6	-44.8	178.7	-69.4	165.4	0	0	0	110.7	Y244 L245 L251 R252	Y244-I248 WeakPolarHBondContact O-CB 3.45Å; Y244-I248 VanDerWaalsContact O-CG1 3.26Å; Y244-I248 WeakPolarHBondContact O-CG1 3.03Å; Y244-I248 PolarHBondContact O-N 3.34Å; L245-I248 PolarHBondContact O-N 2.71Å; I248-L251 PolarHBondContact O-N 2.83Å; I248-R252 WeakPolarHBondContact O-CG 3.24Å; I248-R252 PolarHBondContact O-N 3.43Å
249	R	88.2	Confident	83.5	Confident	161 Å²	161	80.8 Å²	80.8	61%	0.608	39%	0.386	S	S	*	.	H	α-helix	trans	-60.4	-48.5	177.4	-171.8	178.9	178.8	117.9	-2.2	111.6	L245 L246 I247 L251 R252 Q253	L245-R249 WeakPolarHBondContact O-CB 3.38Å; L245-R249 PolarHBondContact O-N 3.05Å; L246-R249 PolarHBondContact O-N 3.37Å; I247-R249 VanDerWaalsContact C-N 3.31Å; I247-R249 PolarHBondContact O-N 2.87Å; R249-L251 VanDerWaalsContact C-N 3.32Å; R249-L251 PolarHBondContact O-N 3.4Å; R249-R252 PolarHBondContact O-N 3.01Å; R249-R252 VanDerWaalsContact O-N 3.16Å; R249-Q253 WeakPolarHBondContact O-CG 3.2Å; R249-Q253 PolarHBondContact O-N 3.47Å
250	S	85.4	Confident	82.8	Confident	7 Å²	7	86.9 Å²	86.9	5%	0.049	41%	0.405	C	S	.	.	H	α-helix	trans	-59.8	-41.3	177.3	-179.3	0	0	0	0	112.1	L246 I247 R252 Q253	L246-S250 WeakPolarHBondContact O-CB 3.32Å; L246-S250 PolarHBondContact O-N 3.37Å; I247-S250 PolarHBondContact O-N 3.12Å; S250-R252 VanDerWaalsContact C-N 3.31Å; S250-R252 PolarHBondContact O-N 3.1Å; S250-Q253 PolarHBondContact O-N 3.13Å
251	L	83.3	Confident	82.1	Confident	14 Å²	14	89.6 Å²	89.6	7%	0.073	42%	0.419	C	S	.	.	H	α-helix	trans	-69.4	-24.1	178	-70.3	178.2	0	0	0	114.1	I165 I247 I248 R249 K262 V266	I165-L251 HydrophobicContact CG2-CD2 4.09Å; I165-L251 HydrophobicContact CG2-CG 4.48Å; I247-L251 HydrophobicContact CG2-CD1 3.73Å; I247-L251 HydrophobicContact CG2-CG 4.13Å; I247-L251 WeakPolarHBondContact O-CB 3.48Å; I247-L251 WeakPolarHBondContact O-CG 3.26Å; I247-L251 PolarHBondContact O-N 3.28Å; I248-L251 PolarHBondContact O-N 2.83Å; R249-L251 VanDerWaalsContact C-N 3.32Å; R249-L251 PolarHBondContact O-N 3.4Å; L251-K262 HydrophobicContact CD1-CG 4.01Å; L251-K262 HydrophobicContact CD2-CB 4.01Å; L251-K262 HydrophobicContact CD2-CD 3.88Å; L251-K262 HydrophobicContact CD2-CG 3.67Å; L251-K262 HydrophobicContact CG-CG 4.34Å; L251-K262 PolarHBondContact O-NZ 3.3Å; L251-V266 HydrophobicContact CD1-CG2 3.95Å
252	R	83.7	Confident	81.6	Confident	210 Å²	210	91.6 Å²	91.6	79%	0.792	42%	0.424	S	S	*	.	H	α-helix	trans	-82.9	-32.8	174.4	-74.3	178.8	-176.6	-172.8	2.1	112.2	I248 R249 S250 G254	I248-R252 WeakPolarHBondContact O-CG 3.24Å; I248-R252 PolarHBondContact O-N 3.43Å; R249-R252 PolarHBondContact O-N 3.01Å; R249-R252 VanDerWaalsContact O-N 3.16Å; S250-R252 VanDerWaalsContact C-N 3.31Å; S250-R252 PolarHBondContact O-N 3.1Å; R252-G254 PolarHBondContact O-N 2.77Å; R252-G254 VanDerWaalsContact O-N 3.11Å
253	Q	83.8	Confident	81	Confident	125 Å²	125	91.6 Å²	91.6	58%	0.584	43%	0.427	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.2	6.4	179.6	-73.2	177.5	-27.3	0	0	114.3	R249 S250 L255	R249-Q253 WeakPolarHBondContact O-CG 3.2Å; R249-Q253 PolarHBondContact O-N 3.47Å; S250-Q253 PolarHBondContact O-N 3.13Å; Q253-L255 VanDerWaalsContact C-N 3.35Å; Q253-L255 PolarHBondContact O-N 2.52Å
254	G	68.5	Low	80.6	Confident	58 Å²	58	93.2 Å²	93.2	60%	0.598	43%	0.433	S	S	*	.	T	Hydrogen-bonded Turn	trans	74.6	19.9	171.6	0	0	0	0	0	114.8	R252 R256	R252-G254 PolarHBondContact O-N 2.77Å; R252-G254 VanDerWaalsContact O-N 3.11Å; G254-R256 PolarHBondContact O-N 3.46Å; G254-R256 VanDerWaalsContact O-N 3.15Å
255	L	70.5	Confident	80.2	Confident	82 Å²	82	93.1 Å²	93.1	43%	0.429	43%	0.433	S	S	.	.			trans	-50.9	125.8	167.8	-121.8	97.2	0	0	0	108	Q253 V257	Q253-L255 VanDerWaalsContact C-N 3.35Å; Q253-L255 PolarHBondContact O-N 2.52Å; L255-V257 HydrophobicContact CB-CG2 4.1Å; L255-V257 HydrophobicContact CD2-CG2 4.38Å; L255-V257 PolarHBondContact O-N 2.03Å
256	R	70.3	Confident	79.8	Confident	258 Å²	258	91.5 Å²	91.5	97%	0.974	43%	0.427	S	S	*	.			trans	-65.9	76.6	177	-81.5	-175.7	175.5	-179.5	-0.7	109.6	G254	G254-R256 PolarHBondContact O-N 3.46Å; G254-R256 VanDerWaalsContact O-N 3.15Å
257	V	72.8	Confident	79.4	Confident	35 Å²	35	92.7 Å²	92.7	21%	0.212	43%	0.427	C	S	.	.			trans	-99.9	135.9	173.5	178.6	0	0	0	0	107.4	I165 L255 K259 L261 K262	I165-V257 HydrophobicContact CG2-CG2 4.47Å; L255-V257 HydrophobicContact CB-CG2 4.1Å; L255-V257 HydrophobicContact CD2-CG2 4.38Å; L255-V257 PolarHBondContact O-N 2.03Å; V257-K259 PolarHBondContact O-N 3.27Å; V257-L261 HydrophobicContact CG1-CB 4.1Å; V257-L261 HydrophobicContact CG1-CD2 4.09Å; V257-L261 HydrophobicContact CG1-CG 4.3Å; V257-K262 HydrophobicContact CG1-CB 4.45Å
258	E	78.3	Confident	79.1	Confident	145 Å²	145	92.9 Å²	92.9	68%	0.678	43%	0.428	S	S	*	.			trans	-51.2	129.8	174.3	-67.6	-175	166.8	0	0	111.1	R260 L261 K262	E258-R260 PolarHBondContact O-N 3.16Å; E258-R260 VanDerWaalsContact O-N 3.08Å; E258-L261 HydrophobicContact CB-CB 4.24Å; E258-L261 PolarHBondContact O-N 3.35Å; E258-K262 PolarHBondContact O-N 3.46Å
259	K	77.2	Confident	78.9	Confident	189 Å²	189	90.5 Å²	90.5	82%	0.822	42%	0.415	S	S	*	.	H	α-helix	trans	-52.6	-36.3	-178.9	-171.8	177.1	179.1	-179.9	0	112.2	V257 S263	V257-K259 PolarHBondContact O-N 3.27Å; K259-S263 WeakPolarHBondContact O-CB 3.48Å; K259-S263 PolarHBondContact O-N 3.15Å
260	R	76.9	Confident	78.7	Confident	168 Å²	168	85.5 Å²	85.5	63%	0.634	41%	0.409	S	S	*	.	H	α-helix	trans	-64.5	-45.3	176.2	-175.8	176.6	173.1	174.9	-5	112.2	E258 S263 K264 E334	E258-R260 PolarHBondContact O-N 3.16Å; E258-R260 VanDerWaalsContact O-N 3.08Å; R260-S263 PolarHBondContact O-N 3.09Å; R260-K264 WeakPolarHBondContact O-CB 3.32Å; R260-K264 PolarHBondContact O-N 2.85Å; R260-E334 IonicContact CZ-OE1 3.81Å; R260-E334 IonicContact NH2-OE1 2.76Å; R260-E334 PolarHBondContact NH2-OE1 2.97Å
261	L	75.3	Confident	78.9	Confident	57 Å²	57	86.5 Å²	86.5	30%	0.298	41%	0.413	S	S	.	.	H	α-helix	trans	-67	-40.6	178.6	-171.9	62.9	0	0	0	111.2	V257 E258 K264 A265	V257-L261 HydrophobicContact CG1-CB 4.1Å; V257-L261 HydrophobicContact CG1-CD2 4.09Å; V257-L261 HydrophobicContact CG1-CG 4.3Å; E258-L261 HydrophobicContact CB-CB 4.24Å; E258-L261 PolarHBondContact O-N 3.35Å; L261-K264 PolarHBondContact O-N 3.35Å; L261-A265 WeakPolarHBondContact O-CB 3.46Å; L261-A265 PolarHBondContact O-N 2.82Å
262	K	78.1	Confident	79.1	Confident	87 Å²	87	85.8 Å²	85.8	38%	0.378	41%	0.41	S	S	.	.	H	α-helix	trans	-58.8	-51.9	173.3	175.4	170.5	-176.7	167.3	0	112.1	L251 V257 E258 K264 A265 V266	L251-K262 HydrophobicContact CD1-CG 4.01Å; L251-K262 HydrophobicContact CD2-CB 4.01Å; L251-K262 HydrophobicContact CD2-CD 3.88Å; L251-K262 HydrophobicContact CD2-CG 3.67Å; L251-K262 HydrophobicContact CG-CG 4.34Å; L251-K262 PolarHBondContact O-NZ 3.3Å; V257-K262 HydrophobicContact CG1-CB 4.45Å; E258-K262 PolarHBondContact O-N 3.46Å; K262-K264 PolarHBondContact O-N 3.43Å; K262-A265 PolarHBondContact O-N 3.01Å; K262-V266 WeakPolarHBondContact O-CG2 3.42Å; K262-V266 PolarHBondContact O-N 3.1Å
263	S	79.1	Confident	79.3	Confident	67 Å²	67	78.3 Å²	78.3	47%	0.469	39%	0.385	S	S	.	.	H	α-helix	trans	-63.1	-42.4	179.4	177.6	0	0	0	0	112	K259 R260 A265 V266 R267	K259-S263 WeakPolarHBondContact O-CB 3.48Å; K259-S263 PolarHBondContact O-N 3.15Å; R260-S263 PolarHBondContact O-N 3.09Å; S263-A265 VanDerWaalsContact C-N 3.31Å; S263-A265 PolarHBondContact O-N 3.38Å; S263-V266 PolarHBondContact O-N 3.45Å; S263-R267 PolarHBondContact O-N 3Å; S263-R267 VanDerWaalsContact O-N 3.11Å
264	K	81.3	Confident	79.6	Confident	46 Å²	46	74.7 Å²	74.7	20%	0.2	38%	0.376	C	S	.	.	H	α-helix	trans	-58.5	-44	174.6	-176.7	172.6	179.6	166.5	0	111.3	R260 L261 K262 M268 F331 V332	R260-K264 WeakPolarHBondContact O-CB 3.32Å; R260-K264 PolarHBondContact O-N 2.85Å; L261-K264 PolarHBondContact O-N 3.35Å; K262-K264 PolarHBondContact O-N 3.43Å; K264-M268 WeakPolarHBondContact O-CB 3.38Å; K264-M268 PolarHBondContact O-N 2.68Å; K264-M268 VanDerWaalsContact O-N 3.09Å; K264-F331 VanDerWaalsContact CE-O 3.23Å; K264-F331 WeakPolarHBondContact CE-O 3.46Å; K264-V332 PolarHBondContact NZ-O 3.45Å
265	A	78.4	Confident	80.7	Confident	3 Å²	3	72.1 Å²	72.1	3%	0.025	35%	0.349	C	S	.	.	H	α-helix	trans	-64.2	-51.8	178.7	0	0	0	0	0	112.3	I165 L261 K262 S263 R267 M268 I269	I165-A265 HydrophobicContact CD1-CB 3.33Å; L261-A265 WeakPolarHBondContact O-CB 3.46Å; L261-A265 PolarHBondContact O-N 2.82Å; K262-A265 PolarHBondContact O-N 3.01Å; S263-A265 VanDerWaalsContact C-N 3.31Å; S263-A265 PolarHBondContact O-N 3.38Å; A265-R267 VanDerWaalsContact C-N 3.29Å; A265-R267 PolarHBondContact O-N 2.8Å; A265-M268 WeakPolarHBondContact O-CB 3.47Å; A265-M268 PolarHBondContact O-N 3.03Å; A265-M268 VanDerWaalsContact O-N 3.07Å; A265-I269 WeakPolarHBondContact O-CG1 3.13Å; A265-I269 PolarHBondContact O-N 3.18Å
266	V	80.1	Confident	81.6	Confident	74 Å²	74	68.2 Å²	68.2	45%	0.448	33%	0.328	S	S	.	.	H	α-helix	trans	-57.1	-42.5	-179.8	171.7	0	0	0	0	111.9	L251 K262 S263 I269 A270	L251-V266 HydrophobicContact CD1-CG2 3.95Å; K262-V266 WeakPolarHBondContact O-CG2 3.42Å; K262-V266 PolarHBondContact O-N 3.1Å; S263-V266 PolarHBondContact O-N 3.45Å; V266-I269 WeakPolarHBondContact O-CB 3.15Å; V266-I269 PolarHBondContact O-N 2.92Å; V266-A270 PolarHBondContact O-N 2.8Å
267	R	82.9	Confident	82.7	Confident	99 Å²	99	61 Å²	61	37%	0.374	31%	0.308	S	S	.	.	H	α-helix	trans	-65.7	-41.1	177	-175.7	172.4	59.6	-147.8	1.4	112.3	S263 A265 I269 A270 I271 F331	S263-R267 PolarHBondContact O-N 3Å; S263-R267 VanDerWaalsContact O-N 3.11Å; A265-R267 VanDerWaalsContact C-N 3.29Å; A265-R267 PolarHBondContact O-N 2.8Å; R267-I269 VanDerWaalsContact C-N 3.34Å; R267-A270 PolarHBondContact O-N 3.01Å; R267-I271 HydrophobicContact CG-CD1 4.04Å; R267-I271 WeakPolarHBondContact O-CG1 3.46Å; R267-I271 PolarHBondContact O-N 2.95Å; R267-I271 VanDerWaalsContact O-N 3.08Å; R267-F331 VanDerWaalsContact CD-CE1 3.48Å; R267-F331 HydrophobicContact CG-CD2 4.41Å; R267-F331 HydrophobicContact CG-CG 4.42Å; R267-F331 VanDerWaalsContact NE-CG 3.3Å
268	M	81.4	Confident	83.6	Confident	5 Å²	5	62.6 Å²	62.6	3%	0.025	32%	0.318	C	S	.	.	H	α-helix	trans	-64.8	-40.4	177.1	-155.7	-163.9	86.5	0	0	111.4	I157 R161 K264 A265 I271 V272 V332	I157-M268 HydrophobicContact CG2-CE 3.48Å; I157-M268 VanDerWaalsContact CG2-CE 3.48Å; I157-M268 HydrophobicContact CG2-SD 3.79Å; R161-M268 HydrophobicContact CB-CE 4.1Å; R161-M268 HydrophobicContact CG-CE 3.17Å; R161-M268 HydrophobicContact CG-SD 3.53Å; R161-M268 VanDerWaalsContact CG-SD 3.53Å; K264-M268 WeakPolarHBondContact O-CB 3.38Å; K264-M268 PolarHBondContact O-N 2.68Å; K264-M268 VanDerWaalsContact O-N 3.09Å; A265-M268 WeakPolarHBondContact O-CB 3.47Å; A265-M268 PolarHBondContact O-N 3.03Å; A265-M268 VanDerWaalsContact O-N 3.07Å; M268-I271 PolarHBondContact O-N 3.21Å; M268-V272 WeakPolarHBondContact O-CB 3.29Å; M268-V272 VanDerWaalsContact O-CG2 3.3Å; M268-V272 WeakPolarHBondContact O-CG2 3.45Å; M268-V272 PolarHBondContact O-N 3.19Å; M268-V332 HydrophobicContact CG-CG2 3.94Å; M268-V332 HydrophobicContact SD-CG2 3.87Å
269	I	81.4	Confident	84.4	Confident	10 Å²	10	55.7 Å²	55.7	5%	0.051	29%	0.286	C	S	.	.	H	α-helix	trans	-55.5	-51.4	172.5	-67.1	170.2	0	0	0	110.3	Y244 I247 A265 V266 R267 I271 V272 L273	Y244-I269 HydrophobicContact CD1-CB 4.29Å; Y244-I269 HydrophobicContact CD1-CD1 4.06Å; Y244-I269 HydrophobicContact CD1-CG1 3.48Å; Y244-I269 VanDerWaalsContact CD1-CG1 3.48Å; Y244-I269 HydrophobicContact CD1-CG2 4.18Å; Y244-I269 HydrophobicContact CD2-CB 4.43Å; Y244-I269 HydrophobicContact CD2-CG1 4.47Å; Y244-I269 HydrophobicContact CD2-CG2 3.75Å; Y244-I269 HydrophobicContact CE1-CB 4.26Å; Y244-I269 HydrophobicContact CE1-CD1 4.48Å; Y244-I269 HydrophobicContact CE1-CG1 3.51Å; Y244-I269 HydrophobicContact CE2-CB 4.42Å; Y244-I269 HydrophobicContact CE2-CG2 4.13Å; Y244-I269 HydrophobicContact CG-CB 4.31Å; Y244-I269 HydrophobicContact CG-CD1 4.46Å; Y244-I269 HydrophobicContact CG-CG1 3.93Å; Y244-I269 HydrophobicContact CG-CG2 3.71Å; I247-I269 HydrophobicContact CB-CD1 4.19Å; I247-I269 HydrophobicContact CD1-CD1 4.38Å; I247-I269 HydrophobicContact CG2-CD1 3.73Å; A265-I269 WeakPolarHBondContact O-CG1 3.13Å; A265-I269 PolarHBondContact O-N 3.18Å; V266-I269 WeakPolarHBondContact O-CB 3.15Å; V266-I269 PolarHBondContact O-N 2.92Å; R267-I269 VanDerWaalsContact C-N 3.34Å; I269-I271 VanDerWaalsContact C-N 3.34Å; I269-I271 PolarHBondContact O-N 3.35Å; I269-V272 PolarHBondContact O-N 3.23Å; I269-L273 HydrophobicContact CG2-CD1 3.68Å; I269-L273 HydrophobicContact CG2-CG 4.34Å; I269-L273 WeakPolarHBondContact O-CB 3.12Å; I269-L273 WeakPolarHBondContact O-CG 3.33Å; I269-L273 PolarHBondContact O-N 2.86Å
270	A	84.7	Confident	85.1	Confident	57 Å²	57	46.7 Å²	46.7	47%	0.471	25%	0.247	S	C	.	.	H	α-helix	trans	-60.2	-43.4	-178.2	0	0	0	0	0	112.2	V266 R267 A274	V266-A270 PolarHBondContact O-N 2.8Å; R267-A270 PolarHBondContact O-N 3.01Å; A270-A274 VanDerWaalsContact O-CB 3.28Å; A270-A274 WeakPolarHBondContact O-CB 3.32Å; A270-A274 PolarHBondContact O-N 3.44Å
271	I	88.8	Confident	85.9	Confident	27 Å²	27	40.3 Å²	40.3	14%	0.138	23%	0.226	C	C	.	.	H	α-helix	trans	-66.7	-49.7	179.8	-67.4	163.9	0	0	0	111	R267 M268 I269 L273 A274 I275 I327 M328 F331	R267-I271 HydrophobicContact CG-CD1 4.04Å; R267-I271 WeakPolarHBondContact O-CG1 3.46Å; R267-I271 PolarHBondContact O-N 2.95Å; R267-I271 VanDerWaalsContact O-N 3.08Å; M268-I271 PolarHBondContact O-N 3.21Å; I269-I271 VanDerWaalsContact C-N 3.34Å; I269-I271 PolarHBondContact O-N 3.35Å; I271-L273 VanDerWaalsContact C-N 3.34Å; I271-L273 PolarHBondContact O-N 2.9Å; I271-A274 PolarHBondContact O-N 3.45Å; I271-I275 HydrophobicContact CG2-CD1 3.88Å; I271-I275 HydrophobicContact CG2-CG1 4.49Å; I271-I275 WeakPolarHBondContact O-CG1 3.01Å; I271-I275 PolarHBondContact O-N 2.91Å; I271-I327 HydrophobicContact CD1-CG2 4.15Å; I271-M328 HydrophobicContact CG2-CE 4.39Å; I271-F331 HydrophobicContact CD1-CD2 3.22Å; I271-F331 HydrophobicContact CD1-CE2 3.5Å; I271-F331 VanDerWaalsContact CD1-CE2 3.5Å; I271-F331 HydrophobicContact CD1-CG 4.26Å
272	V	88.4	Confident	86.8	Confident	0 Å²	0	39.3 Å²	39.3	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-60.6	-45.3	179.7	171.4	0	0	0	0	110.7	L154 T240 Y244 M268 I269 A274 I275 F276 M328	L154-V272 HydrophobicContact CB-CG1 4.43Å; L154-V272 HydrophobicContact CD2-CG2 4.33Å; T240-V272 HydrophobicContact CG2-CG1 3.97Å; Y244-V272 HydrophobicContact CE2-CB 4.02Å; Y244-V272 HydrophobicContact CE2-CG1 3.84Å; Y244-V272 WeakPolarHBondContact OH-CB 3.06Å; Y244-V272 WeakPolarHBondContact OH-CG1 3.41Å; Y244-V272 VanDerWaalsContact OH-CG2 3.29Å; Y244-V272 WeakPolarHBondContact OH-CG2 3.48Å; M268-V272 WeakPolarHBondContact O-CB 3.29Å; M268-V272 VanDerWaalsContact O-CG2 3.3Å; M268-V272 WeakPolarHBondContact O-CG2 3.45Å; M268-V272 PolarHBondContact O-N 3.19Å; I269-V272 PolarHBondContact O-N 3.23Å; V272-A274 VanDerWaalsContact C-N 3.34Å; V272-A274 PolarHBondContact O-N 3.41Å; V272-I275 PolarHBondContact O-N 3.31Å; V272-F276 HydrophobicContact CG1-CD2 3.76Å; V272-F276 HydrophobicContact CG1-CE2 3.77Å; V272-F276 VanDerWaalsContact O-CD2 3.32Å; V272-F276 WeakPolarHBondContact O-CD2 3.18Å; V272-F276 PolarHBondContact O-N 3.49Å; V272-M328 HydrophobicContact CG2-CE 3.57Å
273	L	87.4	Confident	87.4	Confident	53 Å²	53	35.2 Å²	35.2	28%	0.277	21%	0.205	S	C	.	.	H	α-helix	trans	-62	-41.8	176.6	-74.4	175.1	0	0	0	112	Y244 I269 I271 F276 L277	Y244-L273 HydrophobicContact CD2-CD1 4.04Å; Y244-L273 HydrophobicContact CD2-CD2 3.82Å; Y244-L273 HydrophobicContact CD2-CG 3.72Å; Y244-L273 HydrophobicContact CE2-CD2 4.21Å; Y244-L273 HydrophobicContact CE2-CG 3.92Å; I269-L273 HydrophobicContact CG2-CD1 3.68Å; I269-L273 HydrophobicContact CG2-CG 4.34Å; I269-L273 WeakPolarHBondContact O-CB 3.12Å; I269-L273 WeakPolarHBondContact O-CG 3.33Å; I269-L273 PolarHBondContact O-N 2.86Å; I271-L273 VanDerWaalsContact C-N 3.34Å; I271-L273 PolarHBondContact O-N 2.9Å; L273-F276 PolarHBondContact O-N 3.2Å; L273-L277 WeakPolarHBondContact O-CB 3.33Å; L273-L277 VanDerWaalsContact O-CG 3.24Å; L273-L277 WeakPolarHBondContact O-CG 3.4Å; L273-L277 PolarHBondContact O-N 2.83Å
274	A	90.1	Very high	88	Confident	48 Å²	48	32.4 Å²	32.4	40%	0.397	19%	0.185	S	C	.	.	H	α-helix	trans	-61.2	-44.3	176	0	0	0	0	0	111.6	A270 I271 V272 F276 L277 V278	A270-A274 VanDerWaalsContact O-CB 3.28Å; A270-A274 WeakPolarHBondContact O-CB 3.32Å; A270-A274 PolarHBondContact O-N 3.44Å; I271-A274 PolarHBondContact O-N 3.45Å; V272-A274 VanDerWaalsContact C-N 3.34Å; V272-A274 PolarHBondContact O-N 3.41Å; A274-F276 PolarHBondContact O-N 2.8Å; A274-L277 PolarHBondContact O-N 3.45Å; A274-V278 VanDerWaalsContact O-CB 3.31Å; A274-V278 WeakPolarHBondContact O-CB 3.22Å; A274-V278 VanDerWaalsContact O-CG2 3.31Å; A274-V278 WeakPolarHBondContact O-CG2 3.46Å; A274-V278 PolarHBondContact O-N 3.31Å
275	I	91.5	Very high	88.4	Confident	4 Å²	4	34.2 Å²	34.2	2%	0.021	20%	0.2	C	C	.	.	H	α-helix	trans	-59	-47.6	175	-69.9	169.4	0	0	0	110.5	L154 I271 V272 L277 V278 C279 F280 N321 L324 M328	L154-I275 HydrophobicContact CD1-CG2 3.87Å; I271-I275 HydrophobicContact CG2-CD1 3.88Å; I271-I275 HydrophobicContact CG2-CG1 4.49Å; I271-I275 WeakPolarHBondContact O-CG1 3.01Å; I271-I275 PolarHBondContact O-N 2.91Å; V272-I275 PolarHBondContact O-N 3.31Å; I275-L277 PolarHBondContact O-N 2.89Å; I275-V278 PolarHBondContact O-N 3.49Å; I275-C279 HydrophobicContact CG2-CB 4.4Å; I275-C279 WeakPolarHBondContact O-CA 3.42Å; I275-C279 WeakPolarHBondContact O-CB 3.26Å; I275-C279 PolarHBondContact O-N 3.49Å; I275-F280 HydrophobicContact CG2-CD2 4.27Å; I275-F280 HydrophobicContact CG2-CE2 3.65Å; I275-F280 HydrophobicContact CG2-CZ 4.38Å; I275-N321 WeakPolarHBondContact CG2-OD1 3.44Å; I275-L324 HydrophobicContact CG1-CB 4.45Å; I275-M328 HydrophobicContact CD1-CE 3.96Å
276	F	90.4	Very high	88.8	Confident	1 Å²	1	35.2 Å²	35.2	0%	0.004	20%	0.204	C	C	.	.	I	π-helix	trans	-57.7	-48.9	176.3	-90.2	-78.4	0	0	0	112.6	I151 L154 F233 F237 T240 V272 L273 A274 F280 V281	I151-F276 HydrophobicContact CB-CE1 4.5Å; I151-F276 HydrophobicContact CG1-CE1 4.26Å; I151-F276 HydrophobicContact CG2-CE1 3.94Å; I151-F276 HydrophobicContact CG2-CZ 4.16Å; L154-F276 HydrophobicContact CB-CE2 3.99Å; L154-F276 HydrophobicContact CB-CZ 4.36Å; L154-F276 HydrophobicContact CD1-CE2 4.44Å; F233-F276 HydrophobicContact CE2-CD1 4.08Å; F233-F276 HydrophobicContact CE2-CE1 4.31Å; F237-F276 HydrophobicContact CD2-CD1 4.28Å; T240-F276 HydrophobicContact CG2-CD2 4.17Å; T240-F276 HydrophobicContact CG2-CE2 3.92Å; V272-F276 HydrophobicContact CG1-CD2 3.76Å; V272-F276 HydrophobicContact CG1-CE2 3.77Å; V272-F276 VanDerWaalsContact O-CD2 3.32Å; V272-F276 WeakPolarHBondContact O-CD2 3.18Å; V272-F276 PolarHBondContact O-N 3.49Å; L273-F276 PolarHBondContact O-N 3.2Å; A274-F276 PolarHBondContact O-N 2.8Å; F276-F280 AromaticContact CD1-CD2 3.97Å; F276-F280 HydrophobicContact CD1-CD2 3.97Å; F276-F280 HydrophobicContact CE1-CD2 4.29Å; F276-F280 HydrophobicContact CG-CD2 4.35Å; F276-F280 PolarHBondContact O-N 3.28Å; F276-V281 VanDerWaalsContact O-CG2 3.32Å; F276-V281 WeakPolarHBondContact O-CG2 3.35Å; F276-V281 PolarHBondContact O-N 3.06Å
277	L	91.3	Very high	89	Confident	105 Å²	105	32.1 Å²	32.1	55%	0.55	19%	0.185	S	C	.	.	I	π-helix	trans	-69.8	-34.2	-175.6	-69.8	171.3	0	0	0	113.3	L273 A274 I275 V281 P282	L273-L277 WeakPolarHBondContact O-CB 3.33Å; L273-L277 VanDerWaalsContact O-CG 3.24Å; L273-L277 WeakPolarHBondContact O-CG 3.4Å; L273-L277 PolarHBondContact O-N 2.83Å; A274-L277 PolarHBondContact O-N 3.45Å; I275-L277 PolarHBondContact O-N 2.89Å; L277-V281 HydrophobicContact CD2-CG2 4.43Å; L277-P282 VanDerWaalsContact O-CD 3.27Å; L277-P282 WeakPolarHBondContact O-CD 3.47Å; L277-P282 WeakPolarHBondContact O-CG 3.33Å
278	V	92.8	Very high	89.1	Confident	69 Å²	69	29.1 Å²	29.1	42%	0.418	18%	0.179	S	C	.	.	I	π-helix	trans	-92.3	-44	-176.1	176.8	0	0	0	0	111.6	A274 I275 P282 L317	A274-V278 VanDerWaalsContact O-CB 3.31Å; A274-V278 WeakPolarHBondContact O-CB 3.22Å; A274-V278 VanDerWaalsContact O-CG2 3.31Å; A274-V278 WeakPolarHBondContact O-CG2 3.46Å; A274-V278 PolarHBondContact O-N 3.31Å; I275-V278 PolarHBondContact O-N 3.49Å; V278-P282 WeakPolarHBondContact O-CG 3.34Å; V278-L317 HydrophobicContact CG1-CD2 4.34Å; V278-L317 WeakPolarHBondContact O-CB 3.05Å
279	C	94.3	Very high	89.3	Confident	0 Å²	0	31.5 Å²	31.5	0%	0	19%	0.194	C	C	.	.	I	π-helix	trans	-92.9	-36.5	-170.3	-60.9	0	0	0	0	113.8	I275 L317 T318 N321	I275-C279 HydrophobicContact CG2-CB 4.4Å; I275-C279 WeakPolarHBondContact O-CA 3.42Å; I275-C279 WeakPolarHBondContact O-CB 3.26Å; I275-C279 PolarHBondContact O-N 3.49Å; C279-L317 VanDerWaalsContact CA-O 3.3Å; C279-L317 WeakPolarHBondContact CA-O 3.28Å; C279-L317 VanDerWaalsContact CB-O 3.23Å; C279-L317 WeakPolarHBondContact CB-O 3.12Å; C279-L317 PolarHBondContact SG-O 2.8Å; C279-T318 WeakPolarHBondContact O-CA 3.36Å; C279-T318 PolarHBondContact O-N 3.37Å; C279-T318 PolarHBondContact O-OG1 2.7Å; C279-N321 HydrophobicContact CB-CB 4.24Å
280	F	93.2	Very high	89.2	Confident	0 Å²	0	33 Å²	33	0%	0	20%	0.199	C	C	.	.	I	π-helix	trans	-107.4	-50.1	-170.4	-57.1	-54	0	0	0	113.5	M147 I151 L154 F233 I275 F276 P282 Y283 H284 T318 N321	M147-F280 HydrophobicContact CG-CD1 3.94Å; M147-F280 HydrophobicContact CG-CE1 4Å; I151-F280 HydrophobicContact CD1-CB 4.28Å; I151-F280 HydrophobicContact CD1-CD1 3.85Å; I151-F280 HydrophobicContact CD1-CD2 4.39Å; I151-F280 HydrophobicContact CD1-CE1 4.27Å; I151-F280 HydrophobicContact CD1-CG 3.92Å; I151-F280 HydrophobicContact CG1-CB 4.43Å; I151-F280 HydrophobicContact CG1-CD1 3.84Å; I151-F280 HydrophobicContact CG1-CD2 3.67Å; I151-F280 HydrophobicContact CG1-CE1 3.95Å; I151-F280 HydrophobicContact CG1-CE2 3.8Å; I151-F280 HydrophobicContact CG1-CG 3.72Å; I151-F280 HydrophobicContact CG1-CZ 3.93Å; L154-F280 HydrophobicContact CD1-CE2 3.71Å; L154-F280 HydrophobicContact CD1-CZ 4.35Å; F233-F280 HydrophobicContact CE2-CB 3.77Å; F233-F280 HydrophobicContact CZ-CB 4.5Å; I275-F280 HydrophobicContact CG2-CD2 4.27Å; I275-F280 HydrophobicContact CG2-CE2 3.65Å; I275-F280 HydrophobicContact CG2-CZ 4.38Å; F276-F280 AromaticContact CD1-CD2 3.97Å; F276-F280 HydrophobicContact CD1-CD2 3.97Å; F276-F280 HydrophobicContact CE1-CD2 4.29Å; F276-F280 HydrophobicContact CG-CD2 4.35Å; F276-F280 PolarHBondContact O-N 3.28Å; F280-P282 VanDerWaalsContact C-CD 3.48Å; F280-Y283 PolarHBondContact O-N 3.21Å; F280-H284 PolarHBondContact O-CD2 3.08Å; F280-H284 PolarHBondContact O-N 2.62Å; F280-H284 VanDerWaalsContact O-N 3.12Å; F280-T318 HydrophobicContact CD1-CG2 4.24Å; F280-T318 HydrophobicContact CE1-CG2 4.26Å; F280-N321 HydrophobicContact CE1-CB 4.23Å; F280-N321 HydrophobicContact CZ-CB 3.87Å; F280-N321 VanDerWaalsContact CZ-OD1 3.25Å; F280-N321 WeakPolarHBondContact CZ-OD1 3.34Å
281	V	92.3	Very high	88.8	Confident	34 Å²	34	30.5 Å²	30.5	21%	0.206	18%	0.178	C	C	.	.	H	α-helix	trans	-52.5	-47.2	-178.4	170.7	0	0	0	0	112.4	F233 F237 F276 L277 Y283 H284 V285	F233-V281 HydrophobicContact CE1-CG2 4.22Å; F233-V281 HydrophobicContact CZ-CB 4.47Å; F233-V281 HydrophobicContact CZ-CG2 3.63Å; F237-V281 HydrophobicContact CE2-CG2 4.2Å; F276-V281 VanDerWaalsContact O-CG2 3.32Å; F276-V281 WeakPolarHBondContact O-CG2 3.35Å; F276-V281 PolarHBondContact O-N 3.06Å; L277-V281 HydrophobicContact CD2-CG2 4.43Å; V281-Y283 VanDerWaalsContact C-N 3.3Å; V281-Y283 PolarHBondContact O-N 3.27Å; V281-H284 PolarHBondContact O-N 3.04Å; V281-V285 HydrophobicContact CG1-CG2 4.02Å; V281-V285 WeakPolarHBondContact O-CB 3.35Å; V281-V285 VanDerWaalsContact O-CG2 3.27Å; V281-V285 WeakPolarHBondContact O-CG2 3.34Å; V281-V285 PolarHBondContact O-N 3.1Å
282	P	94.3	Very high	88.4	Confident	36 Å²	36	34.2 Å²	34.2	23%	0.234	20%	0.197	C	C	.	.	H	α-helix	trans	-61.9	-39.5	-176.8	-25.9	38.9	0	0	0	112.3	L277 V278 F280 N286 T314 L317	L277-P282 VanDerWaalsContact O-CD 3.27Å; L277-P282 WeakPolarHBondContact O-CD 3.47Å; L277-P282 WeakPolarHBondContact O-CG 3.33Å; V278-P282 WeakPolarHBondContact O-CG 3.34Å; F280-P282 VanDerWaalsContact C-CD 3.48Å; P282-N286 VanDerWaalsContact O-CB 3.24Å; P282-N286 WeakPolarHBondContact O-CB 3.41Å; P282-N286 PolarHBondContact O-N 2.9Å; P282-T314 HydrophobicContact CB-CG2 3.74Å; P282-T314 WeakPolarHBondContact O-CG2 3.1Å; P282-L317 HydrophobicContact CB-CD1 4.16Å; P282-L317 HydrophobicContact CG-CD1 4.26Å
283	Y	91.7	Very high	87.8	Confident	1 Å²	1	38.4 Å²	38.4	0%	0.004	22%	0.217	C	C	.	.	H	α-helix	trans	-63.9	-50.6	177.7	-177.4	-95.1	0	0	0	112	F143 Y144 M147 E219 F280 V281 V285 N286 R287 T318	F143-Y283 HydrophobicContact CE1-CE2 4.5Å; Y144-Y283 HydrophobicContact CE1-CE1 4.28Å; Y144-Y283 PolarHBondContact OH-OH 3.44Å; M147-Y283 HydrophobicContact CE-CD1 4.36Å; M147-Y283 HydrophobicContact CE-CE1 4.11Å; M147-Y283 HydrophobicContact SD-CD1 3.66Å; M147-Y283 HydrophobicContact SD-CE1 3.83Å; M147-Y283 HydrophobicContact SD-CG 4.46Å; E219-Y283 PolarHBondContact OE1-OH 3.27Å; F280-Y283 PolarHBondContact O-N 3.21Å; V281-Y283 VanDerWaalsContact C-N 3.3Å; V281-Y283 PolarHBondContact O-N 3.27Å; Y283-V285 VanDerWaalsContact C-N 3.33Å; Y283-V285 PolarHBondContact O-N 3.4Å; Y283-N286 PolarHBondContact O-N 3.08Å; Y283-R287 WeakPolarHBondContact O-CB 3.35Å; Y283-R287 PolarHBondContact O-N 3.42Å; Y283-T318 VanDerWaalsContact CB-OG1 3.29Å; Y283-T318 WeakPolarHBondContact CB-OG1 3.28Å
284	H	90.8	Very high	86.9	Confident	8 Å²	8	40.4 Å²	40.4	4%	0.037	22%	0.221	C	C	.	.	H	α-helix	trans	-64.5	-37.8	179.9	-68.6	-69.6	0	0	0	112.5	L229 F233 F280 V281 S288	L229-H284 VanDerWaalsContact CD1-CE1 3.5Å; L229-H284 WeakPolarHBondContact CD1-CE1 3.3Å; L229-H284 WeakPolarHBondContact CD1-ND1 3.36Å; F233-H284 HydrophobicContact CD1-CB 4.04Å; F233-H284 AromaticContact CD1-CD2 3.92Å; F233-H284 AromaticContact CD1-CG 3.94Å; F233-H284 AromaticContact CD2-CD2 3.08Å; F233-H284 WeakPolarHBondContact CD2-CD2 3.47Å; F233-H284 AromaticContact CD2-CE1 3.98Å; F233-H284 AromaticContact CD2-CG 3.85Å; F233-H284 AromaticContact CD2-NE2 3.2Å; F233-H284 WeakPolarHBondContact CD2-NE2 3.39Å; F233-H284 HydrophobicContact CE1-CB 4.37Å; F233-H284 AromaticContact CE2-CD2 3.45Å; F233-H284 VanDerWaalsContact CE2-CD2 3.45Å; F233-H284 WeakPolarHBondContact CE2-CD2 3.38Å; F233-H284 AromaticContact CE2-NE2 3.89Å; F233-H284 HydrophobicContact CG-CB 4.22Å; F233-H284 AromaticContact CG-CD2 3.35Å; F233-H284 WeakPolarHBondContact CG-CD2 3.25Å; F233-H284 AromaticContact CG-CG 3.6Å; F233-H284 AromaticContact CG-ND1 3.99Å; F233-H284 AromaticContact CG-NE2 3.63Å; F280-H284 PolarHBondContact O-CD2 3.08Å; F280-H284 PolarHBondContact O-N 2.62Å; F280-H284 VanDerWaalsContact O-N 3.12Å; V281-H284 PolarHBondContact O-N 3.04Å; H284-S288 WeakPolarHBondContact O-CB 3.46Å; H284-S288 PolarHBondContact O-N 3.18Å; H284-S288 PolarHBondContact O-OG 2.97Å
285	V	89.9	Confident	85.6	Confident	85 Å²	85	45.9 Å²	45.9	52%	0.515	23%	0.232	S	C	.	.	H	α-helix	trans	-64.7	-52.9	174.5	172	0	0	0	0	110.4	V281 Y283 R287 S288 V289	V281-V285 HydrophobicContact CG1-CG2 4.02Å; V281-V285 WeakPolarHBondContact O-CB 3.35Å; V281-V285 VanDerWaalsContact O-CG2 3.27Å; V281-V285 WeakPolarHBondContact O-CG2 3.34Å; V281-V285 PolarHBondContact O-N 3.1Å; Y283-V285 VanDerWaalsContact C-N 3.33Å; Y283-V285 PolarHBondContact O-N 3.4Å; V285-R287 VanDerWaalsContact C-N 3.31Å; V285-R287 PolarHBondContact O-N 3.45Å; V285-S288 PolarHBondContact O-N 2.68Å; V285-S288 VanDerWaalsContact O-N 3.17Å; V285-V289 WeakPolarHBondContact O-CG2 3.18Å; V285-V289 PolarHBondContact O-N 3.41Å
286	N	88.1	Confident	84.2	Confident	23 Å²	23	50.1 Å²	50.1	12%	0.123	26%	0.261	C	S	.	.	H	α-helix	trans	-59.3	-43.2	-179.9	-178.9	75	0	0	0	111.7	P282 Y283 S288 V289 Y290 N311 T314	P282-N286 VanDerWaalsContact O-CB 3.24Å; P282-N286 WeakPolarHBondContact O-CB 3.41Å; P282-N286 PolarHBondContact O-N 2.9Å; Y283-N286 PolarHBondContact O-N 3.08Å; N286-S288 PolarHBondContact O-N 3.24Å; N286-V289 PolarHBondContact O-N 3.47Å; N286-Y290 WeakPolarHBondContact O-CB 3.39Å; N286-Y290 PolarHBondContact O-N 3.45Å; N286-N311 VanDerWaalsContact ND2-CA 3.31Å; N286-N311 WeakPolarHBondContact ND2-CA 3.36Å; N286-N311 PolarHBondContact ND2-N 3.27Å; N286-T314 HydrophobicContact CB-CG2 3.98Å
287	R	84.1	Confident	82.6	Confident	10 Å²	10	54 Å²	54	4%	0.038	30%	0.301	C	S	.	.	H	α-helix	trans	-65.1	-38.6	178.1	-169.3	66.5	171.9	136.3	12.1	112	E219 K220 L229 Y283 V285 Y290 V291	E219-R287 VanDerWaalsContact CB-CZ 3.49Å; E219-R287 PolarHBondContact O-NH1 3.46Å; E219-R287 IonicContact OE2-CZ 2.69Å; E219-R287 IonicContact OE2-NE 3.72Å; E219-R287 PolarHBondContact OE2-NE 3.24Å; E219-R287 IonicContact OE2-NH2 2.74Å; E219-R287 PolarHBondContact OE2-NH2 3.28Å; K220-R287 PolarHBondContact O-NH2 3.42Å; L229-R287 HydrophobicContact CD2-CB 3.77Å; L229-R287 HydrophobicContact CD2-CG 3.35Å; Y283-R287 WeakPolarHBondContact O-CB 3.35Å; Y283-R287 PolarHBondContact O-N 3.42Å; V285-R287 VanDerWaalsContact C-N 3.31Å; V285-R287 PolarHBondContact O-N 3.45Å; R287-Y290 PolarHBondContact O-N 2.8Å; R287-V291 WeakPolarHBondContact O-CG2 3.5Å; R287-V291 PolarHBondContact O-N 3.38Å; R287-V291 VanDerWaalsContact O-N 3.07Å
288	S	84.3	Confident	81.4	Confident	35 Å²	35	52.2 Å²	52.2	25%	0.245	31%	0.309	C	S	.	.	H	α-helix	trans	-64.2	-46.4	175.4	-59.4	0	0	0	0	111.6	H284 V285 N286 Y290 V291 L292	H284-S288 WeakPolarHBondContact O-CB 3.46Å; H284-S288 PolarHBondContact O-N 3.18Å; H284-S288 PolarHBondContact O-OG 2.97Å; V285-S288 PolarHBondContact O-N 2.68Å; V285-S288 VanDerWaalsContact O-N 3.17Å; N286-S288 PolarHBondContact O-N 3.24Å; S288-Y290 PolarHBondContact O-N 2.96Å; S288-V291 PolarHBondContact O-N 2.97Å; S288-L292 WeakPolarHBondContact O-CG 3.4Å; S288-L292 PolarHBondContact O-N 3.14Å; S288-L292 VanDerWaalsContact O-N 3.11Å
289	V	84.6	Confident	80.4	Confident	56 Å²	56	50.6 Å²	50.6	34%	0.339	30%	0.299	S	S	.	.	H	α-helix	trans	-61.2	-44.6	175.7	175.1	0	0	0	0	110.7	V285 N286 V291 L292 H293 L307	V285-V289 WeakPolarHBondContact O-CG2 3.18Å; V285-V289 PolarHBondContact O-N 3.41Å; N286-V289 PolarHBondContact O-N 3.47Å; V289-V291 PolarHBondContact O-N 3.5Å; V289-L292 PolarHBondContact O-N 2.97Å; V289-H293 PolarHBondContact O-CD2 2.88Å; V289-H293 PolarHBondContact O-N 2.93Å; V289-L307 HydrophobicContact CG1-CD2 3.88Å
290	Y	80	Confident	79.8	Confident	42 Å²	42	53.6 Å²	53.6	17%	0.165	32%	0.32	C	S	.	.	H	α-helix	trans	-56.2	-49.2	178	-178.3	-95.5	0	0	0	112	N286 R287 S288 L292 H293 Y294 L307	N286-Y290 WeakPolarHBondContact O-CB 3.39Å; N286-Y290 PolarHBondContact O-N 3.45Å; R287-Y290 PolarHBondContact O-N 2.8Å; S288-Y290 PolarHBondContact O-N 2.96Å; Y290-L292 PolarHBondContact O-N 3.15Å; Y290-H293 PolarHBondContact O-N 3.41Å; Y290-Y294 WeakPolarHBondContact O-CB 3.46Å; Y290-Y294 PolarHBondContact O-N 3.42Å; Y290-L307 HydrophobicContact CD2-CB 4.07Å; Y290-L307 HydrophobicContact CD2-CD1 4.38Å
291	V	77.4	Confident	79.3	Confident	3 Å²	3	56.4 Å²	56.4	2%	0.018	34%	0.339	C	S	.	.	H	α-helix	trans	-66.5	-37.7	-179.2	175.3	0	0	0	0	112	A221 L226 R287 S288 V289 R295	A221-V291 HydrophobicContact CB-CB 4.39Å; A221-V291 HydrophobicContact CB-CG1 4.19Å; A221-V291 HydrophobicContact CB-CG2 4.13Å; L226-V291 HydrophobicContact CB-CG1 4.01Å; L226-V291 HydrophobicContact CD1-CB 4.27Å; L226-V291 HydrophobicContact CD1-CG1 4.5Å; L226-V291 HydrophobicContact CD2-CG1 4.09Å; L226-V291 HydrophobicContact CG-CG1 4.44Å; R287-V291 WeakPolarHBondContact O-CG2 3.5Å; R287-V291 PolarHBondContact O-N 3.38Å; R287-V291 VanDerWaalsContact O-N 3.07Å; S288-V291 PolarHBondContact O-N 2.97Å; V289-V291 PolarHBondContact O-N 3.5Å; V291-R295 WeakPolarHBondContact O-CG 3.48Å
292	L	79.2	Confident	78.8	Confident	106 Å²	106	58 Å²	58	56%	0.555	36%	0.356	S	S	*	.	H	α-helix	trans	-67.2	-44.9	178.4	-71.8	169.5	0	0	0	111.9	L226 S288 V289 Y290	L226-L292 HydrophobicContact CD2-CD2 4.33Å; S288-L292 WeakPolarHBondContact O-CG 3.4Å; S288-L292 PolarHBondContact O-N 3.14Å; S288-L292 VanDerWaalsContact O-N 3.11Å; V289-L292 PolarHBondContact O-N 2.97Å; Y290-L292 PolarHBondContact O-N 3.15Å
293	H	75.8	Confident	78.3	Confident	87 Å²	87	58.9 Å²	58.9	40%	0.403	36%	0.361	S	S	.	.	H	α-helix	trans	-74.1	-34.2	-177.9	-84.9	-83.9	0	0	0	113.7	V289 Y290 R295 S296 T299 L307	V289-H293 PolarHBondContact O-CD2 2.88Å; V289-H293 PolarHBondContact O-N 2.93Å; Y290-H293 PolarHBondContact O-N 3.41Å; H293-R295 PolarHBondContact O-N 3.07Å; H293-S296 PolarHBondContact O-N 2.9Å; H293-S296 VanDerWaalsContact O-N 3.15Å; H293-T299 HydrophobicContact CB-CG2 4.04Å; H293-T299 WeakPolarHBondContact O-CG2 3.36Å; H293-L307 HydrophobicContact CB-CD1 4.26Å
294	Y	68.1	Low	77.8	Confident	95 Å²	95	61 Å²	61	37%	0.373	37%	0.371	S	S	.	.	H	α-helix	trans	-62.7	-24.4	178.1	-167.2	-96.7	0	0	0	112.6	A221 Y290	A221-Y294 HydrophobicContact CB-CD1 3.8Å; A221-Y294 HydrophobicContact CB-CG 4.2Å; Y290-Y294 WeakPolarHBondContact O-CB 3.46Å; Y290-Y294 PolarHBondContact O-N 3.42Å
295	R	63.3	Low	77.4	Confident	164 Å²	164	65.7 Å²	65.7	62%	0.619	39%	0.388	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.3	-20.6	177.5	-69.7	-179.1	75.9	109.5	-0.2	114.2	V291 H293 G297	V291-R295 WeakPolarHBondContact O-CG 3.48Å; H293-R295 PolarHBondContact O-N 3.07Å; R295-G297 VanDerWaalsContact C-N 3.29Å; R295-G297 PolarHBondContact O-N 3.33Å
296	S	61.8	Low	77.2	Confident	92 Å²	92	66.5 Å²	66.5	64%	0.643	39%	0.393	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85	6.2	-170	-56.3	0	0	0	0	114.5	H293 G298	H293-S296 PolarHBondContact O-N 2.9Å; H293-S296 VanDerWaalsContact O-N 3.15Å; S296-G298 PolarHBondContact O-N 3.45Å
297	G	57	Low	77	Confident	82 Å²	82	66.3 Å²	66.3	85%	0.845	39%	0.392	S	S	*	.	S	Bend	trans	63.1	2.6	165.6	0	0	0	0	0	117.8	R295	R295-G297 VanDerWaalsContact C-N 3.29Å; R295-G297 PolarHBondContact O-N 3.33Å
298	G	65.6	Low	77	Confident	69 Å²	69	67.5 Å²	67.5	71%	0.711	40%	0.404	S	S	*	.			trans	-146.8	29.7	-172.1	0	0	0	0	0	114.5	S296 S300	S296-G298 PolarHBondContact O-N 3.45Å; G298-S300 PolarHBondContact O-N 2.81Å
299	T	72.8	Confident	77.2	Confident	35 Å²	35	68.8 Å²	68.8	22%	0.215	41%	0.407	C	S	.	.			trans	-69.9	129.6	179.6	47.9	0	0	0	0	111.6	H293 Q304	H293-T299 HydrophobicContact CB-CG2 4.04Å; H293-T299 WeakPolarHBondContact O-CG2 3.36Å; T299-Q304 PolarHBondContact OG1-NE2 3.36Å; T299-Q304 VanDerWaalsContact OG1-NE2 3.12Å
300	S	82.6	Confident	77.4	Confident	62 Å²	62	66.9 Å²	66.9	43%	0.434	40%	0.399	S	S	.	.			trans	-61.4	154.6	174.3	85.6	0	0	0	0	111.9	G298 A302 T303 Q304	G298-S300 PolarHBondContact O-N 2.81Å; S300-A302 VanDerWaalsContact C-N 3.29Å; S300-A302 PolarHBondContact O-N 2.96Å; S300-T303 WeakPolarHBondContact O-CB 3.22Å; S300-T303 PolarHBondContact O-N 3.44Å; S300-T303 PolarHBondContact OG-N 2.81Å; S300-T303 PolarHBondContact OG-OG1 3.35Å; S300-Q304 PolarHBondContact O-N 3.06Å
301	C	81.3	Confident	77.8	Confident	60 Å²	60	65 Å²	65	41%	0.405	39%	0.392	S	S	.	.	H	α-helix	trans	-59.7	-38.3	179	-161.2	0	0	0	0	113.2	C55 Q304 R305	C55-C301 WeakPolarHBondContact CA-SG 3.31Å; C55-C301 HydrophobicContact CB-CB 4.08Å; C55-C301 WeakPolarHBondContact CB-SG 3.44Å; C55-C301 WeakPolarHBondContact SG-CA 3.37Å; C55-C301 WeakPolarHBondContact SG-CB 3.46Å; C55-C301 CovalentContact SG-SG 2.03Å; C55-C301 PolarHBondContact SG-SG 3.2Å; C301-Q304 PolarHBondContact O-N 3.33Å; C301-R305 PolarHBondContact O-N 3.29Å; C301-R305 VanDerWaalsContact O-N 3.12Å
302	A	82.9	Confident	78.4	Confident	68 Å²	68	65.7 Å²	65.7	56%	0.562	39%	0.394	S	S	*	.	H	α-helix	trans	-63.2	-41.8	173.9	0	0	0	0	0	111.8	S300 R305 V306	S300-A302 VanDerWaalsContact C-N 3.29Å; S300-A302 PolarHBondContact O-N 2.96Å; A302-R305 PolarHBondContact O-N 3.38Å; A302-V306 WeakPolarHBondContact O-CG2 3.33Å; A302-V306 PolarHBondContact O-N 3.34Å
303	T	83.1	Confident	79.1	Confident	53 Å²	53	64.3 Å²	64.3	33%	0.325	39%	0.387	S	S	.	.	H	α-helix	trans	-63.4	-43.6	177.9	-51.1	0	0	0	0	111.5	S300 R305 V306 L307	S300-T303 WeakPolarHBondContact O-CB 3.22Å; S300-T303 PolarHBondContact O-N 3.44Å; S300-T303 PolarHBondContact OG-N 2.81Å; S300-T303 PolarHBondContact OG-OG1 3.35Å; T303-R305 VanDerWaalsContact C-N 3.34Å; T303-R305 PolarHBondContact O-N 2.99Å; T303-V306 PolarHBondContact O-N 3Å; T303-L307 HydrophobicContact CG2-CD1 4.08Å; T303-L307 HydrophobicContact CG2-CG 4.46Å; T303-L307 WeakPolarHBondContact O-CB 3.43Å; T303-L307 WeakPolarHBondContact O-CG 3.19Å; T303-L307 PolarHBondContact O-N 3.29Å
304	Q	80.3	Confident	80	Confident	47 Å²	47	60.8 Å²	60.8	22%	0.22	37%	0.371	C	S	.	.	H	α-helix	trans	-62	-41.9	177.1	-70	-176.5	-13.8	0	0	111.9	T299 S300 C301 L307 A308	T299-Q304 PolarHBondContact OG1-NE2 3.36Å; T299-Q304 VanDerWaalsContact OG1-NE2 3.12Å; S300-Q304 PolarHBondContact O-N 3.06Å; C301-Q304 PolarHBondContact O-N 3.33Å; Q304-L307 PolarHBondContact O-N 3Å; Q304-A308 WeakPolarHBondContact O-CB 3.46Å; Q304-A308 PolarHBondContact O-N 2.79Å
305	R	83.1	Confident	81.2	Confident	106 Å²	106	56.4 Å²	56.4	40%	0.4	35%	0.354	S	S	.	.	H	α-helix	trans	-62.2	-45.2	175.6	-173.6	173.9	-178.2	157.6	7.6	112.4	Q57 E62 C301 A302 T303 A308 L309	Q57-R305 PolarHBondContact O-NH2 2.66Å; E62-R305 IonicContact OE1-NH2 3.14Å; C301-R305 PolarHBondContact O-N 3.29Å; C301-R305 VanDerWaalsContact O-N 3.12Å; A302-R305 PolarHBondContact O-N 3.38Å; T303-R305 VanDerWaalsContact C-N 3.34Å; T303-R305 PolarHBondContact O-N 2.99Å; R305-A308 PolarHBondContact O-N 2.89Å; R305-L309 WeakPolarHBondContact O-CB 3.48Å; R305-L309 PolarHBondContact O-N 3.07Å
306	V	86.3	Confident	82.7	Confident	102 Å²	102	49 Å²	49	62%	0.618	33%	0.327	S	S	*	.	H	α-helix	trans	-61.8	-44.6	177.6	169.5	0	0	0	0	111.1	A302 T303 L309 G310	A302-V306 WeakPolarHBondContact O-CG2 3.33Å; A302-V306 PolarHBondContact O-N 3.34Å; T303-V306 PolarHBondContact O-N 3Å; V306-L309 PolarHBondContact O-N 3.49Å; V306-G310 PolarHBondContact O-N 2.94Å
307	L	84.4	Confident	84.4	Confident	19 Å²	19	46.9 Å²	46.9	10%	0.099	31%	0.309	C	S	.	.	H	α-helix	trans	-66.1	-38.8	178.4	-72	172.9	0	0	0	112.5	V289 Y290 H293 T303 Q304 G310 N311	V289-L307 HydrophobicContact CG1-CD2 3.88Å; Y290-L307 HydrophobicContact CD2-CB 4.07Å; Y290-L307 HydrophobicContact CD2-CD1 4.38Å; H293-L307 HydrophobicContact CB-CD1 4.26Å; T303-L307 HydrophobicContact CG2-CD1 4.08Å; T303-L307 HydrophobicContact CG2-CG 4.46Å; T303-L307 WeakPolarHBondContact O-CB 3.43Å; T303-L307 WeakPolarHBondContact O-CG 3.19Å; T303-L307 PolarHBondContact O-N 3.29Å; Q304-L307 PolarHBondContact O-N 3Å; L307-G310 PolarHBondContact O-N 3.44Å; L307-N311 WeakPolarHBondContact O-CB 3.37Å; L307-N311 PolarHBondContact O-N 2.93Å
308	A	83.1	Confident	86.2	Confident	34 Å²	34	43 Å²	43	28%	0.281	27%	0.268	S	S	.	.	H	α-helix	trans	-65.3	-45.3	175.9	0	0	0	0	0	111.8	Q304 R305 N311 R312	Q304-A308 WeakPolarHBondContact O-CB 3.46Å; Q304-A308 PolarHBondContact O-N 2.79Å; R305-A308 PolarHBondContact O-N 2.89Å; A308-N311 PolarHBondContact O-N 3.2Å; A308-R312 PolarHBondContact O-N 3.21Å
309	L	87.6	Confident	87.5	Confident	62 Å²	62	39.9 Å²	39.9	33%	0.325	24%	0.236	S	C	.	.	H	α-helix	trans	-62.9	-44.7	174.1	179.8	61.3	0	0	0	111.5	F66 R305 V306 N311 R312 I313	F66-L309 HydrophobicContact CE2-CD1 4.24Å; F66-L309 HydrophobicContact CZ-CD1 3.99Å; R305-L309 WeakPolarHBondContact O-CB 3.48Å; R305-L309 PolarHBondContact O-N 3.07Å; V306-L309 PolarHBondContact O-N 3.49Å; L309-N311 VanDerWaalsContact C-N 3.26Å; L309-N311 PolarHBondContact O-N 3.43Å; L309-R312 WeakPolarHBondContact O-CB 3.39Å; L309-R312 PolarHBondContact O-N 2.91Å; L309-R312 VanDerWaalsContact O-N 3.14Å; L309-I313 HydrophobicContact CD1-CD1 4.07Å; L309-I313 HydrophobicContact CD1-CG1 4.27Å; L309-I313 HydrophobicContact CD2-CD1 4.45Å; L309-I313 HydrophobicContact CG-CD1 3.85Å; L309-I313 HydrophobicContact CG-CG1 4.45Å; L309-I313 WeakPolarHBondContact O-CG1 3.41Å; L309-I313 PolarHBondContact O-N 2.96Å
310	G	90.3	Very high	88.6	Confident	16 Å²	16	40.2 Å²	40.2	17%	0.165	24%	0.236	C	C	.	.	H	α-helix	trans	-56.7	-39.9	174.6	0	0	0	0	0	112.1	V306 L307 R312 I313 T314	V306-G310 PolarHBondContact O-N 2.94Å; L307-G310 PolarHBondContact O-N 3.44Å; G310-R312 PolarHBondContact O-N 2.86Å; G310-I313 PolarHBondContact O-N 3.1Å; G310-T314 WeakPolarHBondContact O-CB 3.48Å; G310-T314 VanDerWaalsContact O-CG2 3.26Å; G310-T314 WeakPolarHBondContact O-CG2 3.01Å; G310-T314 PolarHBondContact O-N 3.35Å; G310-T314 PolarHBondContact O-OG1 2.85Å
311	N	87.9	Confident	89.1	Confident	2 Å²	2	37.3 Å²	37.3	1%	0.011	22%	0.216	C	C	.	.	H	α-helix	trans	-65.6	-39.5	177.1	-160	36.4	0	0	0	112.5	Y217 N286 L307 A308 L309 T314 S315	Y217-N311 VanDerWaalsContact C-ND2 3.29Å; Y217-N311 VanDerWaalsContact CA-ND2 3.35Å; Y217-N311 WeakPolarHBondContact CA-ND2 3.47Å; Y217-N311 PolarHBondContact O-ND2 3.48Å; N286-N311 VanDerWaalsContact ND2-CA 3.31Å; N286-N311 WeakPolarHBondContact ND2-CA 3.36Å; N286-N311 PolarHBondContact ND2-N 3.27Å; L307-N311 WeakPolarHBondContact O-CB 3.37Å; L307-N311 PolarHBondContact O-N 2.93Å; A308-N311 PolarHBondContact O-N 3.2Å; L309-N311 VanDerWaalsContact C-N 3.26Å; L309-N311 PolarHBondContact O-N 3.43Å; N311-T314 PolarHBondContact O-OG1 3.34Å; N311-S315 VanDerWaalsContact O-CB 3.22Å; N311-S315 WeakPolarHBondContact O-CB 3.42Å; N311-S315 PolarHBondContact O-N 2.88Å; N311-S315 PolarHBondContact O-OG 3.01Å
312	R	90.4	Very high	89.6	Confident	18 Å²	18	34.6 Å²	34.6	7%	0.068	20%	0.198	C	C	.	.	H	α-helix	trans	-63.7	-51.4	174	-67.9	177.3	-119.1	-101.4	0.5	112	E58 F66 Y217 A308 L309 G310 T314 S315 C316	E58-R312 IonicContact OE1-CZ 3.3Å; E58-R312 IonicContact OE1-NH1 2.9Å; E58-R312 PolarHBondContact OE1-NH1 3.23Å; E58-R312 IonicContact OE1-NH2 3.93Å; E58-R312 PolarHBondContact OE1-NH2 3.27Å; E58-R312 IonicContact OE2-CZ 2.8Å; E58-R312 IonicContact OE2-NH1 2.72Å; E58-R312 PolarHBondContact OE2-NH1 3.14Å; E58-R312 IonicContact OE2-NH2 3.25Å; F66-R312 HydrophobicContact CD1-CB 4.49Å; F66-R312 HydrophobicContact CE1-CB 3.75Å; F66-R312 HydrophobicContact CE2-CB 4.11Å; F66-R312 HydrophobicContact CZ-CB 3.54Å; F66-R312 HydrophobicContact CZ-CG 4.39Å; Y217-R312 HydrophobicContact CD1-CB 4.14Å; Y217-R312 HydrophobicContact CD1-CG 3.59Å; Y217-R312 HydrophobicContact CD2-CG 4.24Å; Y217-R312 HydrophobicContact CE1-CB 4.08Å; Y217-R312 HydrophobicContact CE1-CG 3.82Å; Y217-R312 HydrophobicContact CE2-CG 4.43Å; Y217-R312 HydrophobicContact CG-CG 3.84Å; A308-R312 PolarHBondContact O-N 3.21Å; L309-R312 WeakPolarHBondContact O-CB 3.39Å; L309-R312 PolarHBondContact O-N 2.91Å; L309-R312 VanDerWaalsContact O-N 3.14Å; G310-R312 PolarHBondContact O-N 2.86Å; R312-T314 PolarHBondContact O-N 3.46Å; R312-S315 WeakPolarHBondContact O-CB 3.21Å; R312-S315 PolarHBondContact O-N 3.16Å; R312-C316 PolarHBondContact O-N 3.07Å; R312-C316 PolarHBondContact O-SG 3.44Å; R312-C316 VanDerWaalsContact O-SG 3.38Å
313	I	93.9	Very high	90.1	Very high	78 Å²	78	32.1 Å²	32.1	40%	0.4	18%	0.178	S	C	.	.	H	α-helix	trans	-59.3	-50.1	-178.5	-67.9	171.9	0	0	0	110	F66 L309 G310 S315 C316 L317	F66-I313 HydrophobicContact CE1-CG1 4.3Å; F66-I313 HydrophobicContact CZ-CG1 4.14Å; L309-I313 HydrophobicContact CD1-CD1 4.07Å; L309-I313 HydrophobicContact CD1-CG1 4.27Å; L309-I313 HydrophobicContact CD2-CD1 4.45Å; L309-I313 HydrophobicContact CG-CD1 3.85Å; L309-I313 HydrophobicContact CG-CG1 4.45Å; L309-I313 WeakPolarHBondContact O-CG1 3.41Å; L309-I313 PolarHBondContact O-N 2.96Å; G310-I313 PolarHBondContact O-N 3.1Å; I313-S315 VanDerWaalsContact C-N 3.31Å; I313-S315 PolarHBondContact O-N 3.32Å; I313-C316 WeakPolarHBondContact O-CB 3.28Å; I313-C316 PolarHBondContact O-N 2.85Å; I313-C316 VanDerWaalsContact O-N 3.15Å; I313-L317 HydrophobicContact CG2-CD1 4.4Å; I313-L317 WeakPolarHBondContact O-CG 3.37Å; I313-L317 PolarHBondContact O-N 3.49Å
314	T	94.8	Very high	90.5	Very high	13 Å²	13	31.8 Å²	31.8	8%	0.08	17%	0.174	C	C	.	.	H	α-helix	trans	-66.9	-33.2	-179.3	55.6	0	0	0	0	112.4	P282 N286 G310 N311 R312 L317 T318	P282-T314 HydrophobicContact CB-CG2 3.74Å; P282-T314 WeakPolarHBondContact O-CG2 3.1Å; N286-T314 HydrophobicContact CB-CG2 3.98Å; G310-T314 WeakPolarHBondContact O-CB 3.48Å; G310-T314 VanDerWaalsContact O-CG2 3.26Å; G310-T314 WeakPolarHBondContact O-CG2 3.01Å; G310-T314 PolarHBondContact O-N 3.35Å; G310-T314 PolarHBondContact O-OG1 2.85Å; N311-T314 PolarHBondContact O-OG1 3.34Å; R312-T314 PolarHBondContact O-N 3.46Å; T314-L317 WeakPolarHBondContact O-CB 3.04Å; T314-L317 PolarHBondContact O-N 2.94Å; T314-T318 PolarHBondContact O-N 3.41Å; T314-T318 PolarHBondContact O-OG1 2.76Å; T314-T318 VanDerWaalsContact O-OG1 3.05Å
315	S	93.1	Very high	90.8	Very high	2 Å²	2	29.6 Å²	29.6	1%	0.014	16%	0.163	C	C	.	.	H	α-helix	trans	-64.2	-38.1	171.5	-62.5	0	0	0	0	112.7	N311 R312 I313 T318 S319	N311-S315 VanDerWaalsContact O-CB 3.22Å; N311-S315 WeakPolarHBondContact O-CB 3.42Å; N311-S315 PolarHBondContact O-N 2.88Å; N311-S315 PolarHBondContact O-OG 3.01Å; R312-S315 WeakPolarHBondContact O-CB 3.21Å; R312-S315 PolarHBondContact O-N 3.16Å; I313-S315 VanDerWaalsContact C-N 3.31Å; I313-S315 PolarHBondContact O-N 3.32Å; S315-T318 PolarHBondContact O-N 3.4Å; S315-S319 PolarHBondContact O-N 2.03Å
316	C	95.1	Very high	91	Very high	8 Å²	8	25.6 Å²	25.6	5%	0.054	15%	0.151	C	C	.	.	H	α-helix	trans	-62.9	-44.3	171.6	-70.5	0	0	0	0	111.3	F66 F69 Y70 R312 I313 T318 S319 L320	F66-C316 VanDerWaalsContact CD1-SG 3.54Å; F69-C316 HydrophobicContact CD1-CB 3.74Å; F69-C316 HydrophobicContact CE1-CB 3.38Å; F69-C316 WeakPolarHBondContact CE1-O 3.39Å; F69-C316 HydrophobicContact CE2-CB 4.34Å; F69-C316 HydrophobicContact CG-CB 4.38Å; F69-C316 HydrophobicContact CZ-CB 3.72Å; F69-C316 WeakPolarHBondContact CZ-O 3.49Å; Y70-C316 PolarHBondContact OH-SG 2.98Å; Y70-C316 VanDerWaalsContact OH-SG 3.34Å; R312-C316 PolarHBondContact O-N 3.07Å; R312-C316 PolarHBondContact O-SG 3.44Å; R312-C316 VanDerWaalsContact O-SG 3.38Å; I313-C316 WeakPolarHBondContact O-CB 3.28Å; I313-C316 PolarHBondContact O-N 2.85Å; I313-C316 VanDerWaalsContact O-N 3.15Å; C316-T318 VanDerWaalsContact C-N 3.28Å; C316-T318 PolarHBondContact O-N 3.19Å; C316-S319 PolarHBondContact O-N 3.46Å; C316-S319 PolarHBondContact O-OG 3.12Å; C316-L320 PolarHBondContact O-N 2.95Å; C316-L320 VanDerWaalsContact O-N 3.08Å
317	L	96.1	Very high	90.9	Very high	48 Å²	48	24.5 Å²	24.5	25%	0.251	14%	0.141	S	C	.	.	H	α-helix	trans	-60.9	-38.7	176.3	-65.6	176.8	0	0	0	111.9	V278 C279 P282 I313 T314 L320	V278-L317 HydrophobicContact CG1-CD2 4.34Å; V278-L317 WeakPolarHBondContact O-CB 3.05Å; C279-L317 VanDerWaalsContact CA-O 3.3Å; C279-L317 WeakPolarHBondContact CA-O 3.28Å; C279-L317 VanDerWaalsContact CB-O 3.23Å; C279-L317 WeakPolarHBondContact CB-O 3.12Å; C279-L317 PolarHBondContact SG-O 2.8Å; P282-L317 HydrophobicContact CB-CD1 4.16Å; P282-L317 HydrophobicContact CG-CD1 4.26Å; I313-L317 HydrophobicContact CG2-CD1 4.4Å; I313-L317 WeakPolarHBondContact O-CG 3.37Å; I313-L317 PolarHBondContact O-N 3.49Å; T314-L317 WeakPolarHBondContact O-CB 3.04Å; T314-L317 PolarHBondContact O-N 2.94Å; L317-L320 WeakPolarHBondContact O-CB 3.37Å; L317-L320 PolarHBondContact O-N 3.43Å
318	T	95.3	Very high	90.9	Very high	0 Å²	0	23.7 Å²	23.7	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-65.4	-43.3	175.7	-58.7	0	0	0	0	112.5	F143 M147 C279 F280 Y283 T314 S315 C316 L320 N321	F143-T318 HydrophobicContact CE2-CG2 4.39Å; F143-T318 HydrophobicContact CZ-CG2 3.97Å; M147-T318 HydrophobicContact CB-CG2 4.02Å; M147-T318 HydrophobicContact CG-CG2 3.66Å; M147-T318 HydrophobicContact SD-CG2 3.76Å; C279-T318 WeakPolarHBondContact O-CA 3.36Å; C279-T318 PolarHBondContact O-N 3.37Å; C279-T318 PolarHBondContact O-OG1 2.7Å; F280-T318 HydrophobicContact CD1-CG2 4.24Å; F280-T318 HydrophobicContact CE1-CG2 4.26Å; Y283-T318 VanDerWaalsContact CB-OG1 3.29Å; Y283-T318 WeakPolarHBondContact CB-OG1 3.28Å; T314-T318 PolarHBondContact O-N 3.41Å; T314-T318 PolarHBondContact O-OG1 2.76Å; T314-T318 VanDerWaalsContact O-OG1 3.05Å; S315-T318 PolarHBondContact O-N 3.4Å; C316-T318 VanDerWaalsContact C-N 3.28Å; C316-T318 PolarHBondContact O-N 3.19Å; T318-L320 VanDerWaalsContact C-N 3.26Å; T318-L320 PolarHBondContact O-N 2.72Å; T318-N321 VanDerWaalsContact O-CB 3.31Å; T318-N321 WeakPolarHBondContact O-CB 3.48Å; T318-N321 PolarHBondContact O-N 2.85Å
319	S	94.3	Very high	90.9	Very high	4 Å²	4	22 Å²	22	3%	0.028	12%	0.123	C	C	.	.	H	α-helix	trans	-66.2	-30.8	178.7	70.9	0	0	0	0	112.7	D73 S315 C316 N321 G322	D73-S319 WeakPolarHBondContact OD2-CB 3.33Å; D73-S319 PolarHBondContact OD2-OG 3.34Å; S315-S319 PolarHBondContact O-N 2.03Å; C316-S319 PolarHBondContact O-N 3.46Å; C316-S319 PolarHBondContact O-OG 3.12Å; S319-N321 PolarHBondContact O-N 2.93Å; S319-G322 PolarHBondContact O-N 3.36Å
320	L	94.2	Very high	90.7	Very high	43 Å²	43	21.8 Å²	21.8	23%	0.225	12%	0.12	C	C	.	.	H	α-helix	trans	-58	-20	176.5	-163.6	66	0	0	0	113.6	F69 C316 L317 T318 G322 A323 L324	F69-L320 HydrophobicContact CE2-CD1 4.24Å; F69-L320 HydrophobicContact CZ-CB 4.25Å; F69-L320 HydrophobicContact CZ-CD1 4.14Å; C316-L320 PolarHBondContact O-N 2.95Å; C316-L320 VanDerWaalsContact O-N 3.08Å; L317-L320 WeakPolarHBondContact O-CB 3.37Å; L317-L320 PolarHBondContact O-N 3.43Å; T318-L320 VanDerWaalsContact C-N 3.26Å; T318-L320 PolarHBondContact O-N 2.72Å; L320-G322 VanDerWaalsContact C-N 3.25Å; L320-G322 PolarHBondContact O-N 3.18Å; L320-A323 HydrophobicContact CD1-CB 4.17Å; L320-A323 PolarHBondContact O-N 3.47Å; L320-A323 VanDerWaalsContact O-N 3.1Å; L320-L324 HydrophobicContact CD2-CD1 4.24Å; L320-L324 HydrophobicContact CG-CD1 4.11Å; L320-L324 HydrophobicContact CG-CG 4.16Å; L320-L324 WeakPolarHBondContact O-CG 3.1Å; L320-L324 PolarHBondContact O-N 2.91Å; L320-L324 VanDerWaalsContact O-N 3.08Å
321	N	93.6	Very high	90	Very high	0 Å²	0	23.4 Å²	23.4	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-47.9	-50.5	173.5	175.3	83	0	0	0	111.3	D109 S150 I275 C279 F280 T318 S319 A323 L324 D325	D109-N321 PolarHBondContact OD1-ND2 2.92Å; S150-N321 WeakPolarHBondContact CB-ND2 3.49Å; S150-N321 PolarHBondContact OG-ND2 2.98Å; I275-N321 WeakPolarHBondContact CG2-OD1 3.44Å; C279-N321 HydrophobicContact CB-CB 4.24Å; F280-N321 HydrophobicContact CE1-CB 4.23Å; F280-N321 HydrophobicContact CZ-CB 3.87Å; F280-N321 VanDerWaalsContact CZ-OD1 3.25Å; F280-N321 WeakPolarHBondContact CZ-OD1 3.34Å; T318-N321 VanDerWaalsContact O-CB 3.31Å; T318-N321 WeakPolarHBondContact O-CB 3.48Å; T318-N321 PolarHBondContact O-N 2.85Å; S319-N321 PolarHBondContact O-N 2.93Å; N321-A323 VanDerWaalsContact C-N 3.27Å; N321-A323 PolarHBondContact O-N 2.89Å; N321-L324 PolarHBondContact O-N 3.19Å; N321-D325 PolarHBondContact ND2-OD2 3.43Å; N321-D325 PolarHBondContact O-N 2.77Å
322	G	92.2	Very high	89.3	Confident	4 Å²	4	23.7 Å²	23.7	4%	0.041	12%	0.124	C	C	.	.	H	α-helix	trans	-64.2	-30.7	-176.5	0	0	0	0	0	113.2	N81 S319 L320 P326	N81-G322 PolarHBondContact ND2-O 3.11Å; S319-G322 PolarHBondContact O-N 3.36Å; L320-G322 VanDerWaalsContact C-N 3.25Å; L320-G322 PolarHBondContact O-N 3.18Å; G322-P326 WeakPolarHBondContact O-CD 3.49Å
323	A	92.5	Very high	88.6	Confident	15 Å²	15	23.1 Å²	23.1	12%	0.124	12%	0.123	C	C	.	.	H	α-helix	trans	-77.2	-22.3	174.3	0	0	0	0	0	113.3	D73 L76 A77 L320 N321 P326	D73-A323 WeakPolarHBondContact OD1-CB 3.3Å; L76-A323 HydrophobicContact CB-CB 3.84Å; L76-A323 HydrophobicContact CD1-CB 4.46Å; A77-A323 HydrophobicContact CB-CB 4.48Å; L320-A323 HydrophobicContact CD1-CB 4.17Å; L320-A323 PolarHBondContact O-N 3.47Å; L320-A323 VanDerWaalsContact O-N 3.1Å; N321-A323 VanDerWaalsContact C-N 3.27Å; N321-A323 PolarHBondContact O-N 2.89Å; A323-P326 WeakPolarHBondContact O-CD 3.14Å
324	L	91.4	Very high	87.7	Confident	47 Å²	47	23.9 Å²	23.9	25%	0.246	13%	0.125	C	C	.	.	H	α-helix	trans	-88	-23.5	178.3	-65.7	173.7	0	0	0	113	I275 L320 N321 P326 I327	I275-L324 HydrophobicContact CG1-CB 4.45Å; L320-L324 HydrophobicContact CD2-CD1 4.24Å; L320-L324 HydrophobicContact CG-CD1 4.11Å; L320-L324 HydrophobicContact CG-CG 4.16Å; L320-L324 WeakPolarHBondContact O-CG 3.1Å; L320-L324 PolarHBondContact O-N 2.91Å; L320-L324 VanDerWaalsContact O-N 3.08Å; N321-L324 PolarHBondContact O-N 3.19Å; L324-P326 VanDerWaalsContact C-CD 3.47Å; L324-I327 HydrophobicContact CD2-CD1 3.88Å; L324-I327 WeakPolarHBondContact O-CB 2.98Å; L324-I327 WeakPolarHBondContact O-CG1 3.47Å; L324-I327 PolarHBondContact O-N 3.32Å
325	D	88.4	Confident	86.8	Confident	0 Å²	0	28.5 Å²	28.5	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-59.4	-31.8	-179.8	-74.9	-34.3	0	0	0	115.2	L105 N321 I327 M328 Y329	L105-D325 HydrophobicContact CD2-CB 4.38Å; N321-D325 PolarHBondContact ND2-OD2 3.43Å; N321-D325 PolarHBondContact O-N 2.77Å; D325-I327 PolarHBondContact O-N 2.89Å; D325-I327 VanDerWaalsContact O-N 3.15Å; D325-M328 CarbonylContact O-C 3.59Å; D325-M328 WeakPolarHBondContact O-CA 3.21Å; D325-M328 VanDerWaalsContact O-CB 3.23Å; D325-M328 WeakPolarHBondContact O-CB 3.45Å; D325-M328 PolarHBondContact O-N 3.37Å; D325-Y329 HydrophobicContact CB-CE1 4.37Å; D325-Y329 HydrophobicContact CB-CE2 4.14Å; D325-Y329 WeakPolarHBondContact O-CD2 3.28Å; D325-Y329 PolarHBondContact O-N 3.39Å
326	P	85.8	Confident	86.1	Confident	23 Å²	23	28.6 Å²	28.6	15%	0.149	14%	0.144	C	C	.	.	H	α-helix	trans	-52.6	-31.7	166.7	-30.4	37.4	0	0	0	115.4	G322 A323 L324 M328 Y329 F330 F336	G322-P326 WeakPolarHBondContact O-CD 3.49Å; A323-P326 WeakPolarHBondContact O-CD 3.14Å; L324-P326 VanDerWaalsContact C-CD 3.47Å; P326-M328 VanDerWaalsContact C-N 3.34Å; P326-Y329 VanDerWaalsContact CA-CD2 3.44Å; P326-Y329 HydrophobicContact CB-CD2 4.36Å; P326-Y329 HydrophobicContact CG-CD2 4.42Å; P326-Y329 HydrophobicContact CG-CE2 4.4Å; P326-Y329 PolarHBondContact O-N 3.03Å; P326-F330 PolarHBondContact O-N 3.31Å; P326-F336 HydrophobicContact CB-CZ 4.17Å; P326-F336 WeakPolarHBondContact O-CE1 2.91Å
327	I	85.3	Confident	85.5	Confident	79 Å²	79	31.7 Å²	31.7	41%	0.405	16%	0.155	S	C	.	.	H	α-helix	trans	-65.9	-42.4	173.9	-56.7	174.8	0	0	0	109.4	I271 L324 D325 F330 F331	I271-I327 HydrophobicContact CD1-CG2 4.15Å; L324-I327 HydrophobicContact CD2-CD1 3.88Å; L324-I327 WeakPolarHBondContact O-CB 2.98Å; L324-I327 WeakPolarHBondContact O-CG1 3.47Å; L324-I327 PolarHBondContact O-N 3.32Å; D325-I327 PolarHBondContact O-N 2.89Å; D325-I327 VanDerWaalsContact O-N 3.15Å; I327-F330 PolarHBondContact O-N 3.17Å; I327-F331 HydrophobicContact CG2-CD2 4.17Å; I327-F331 HydrophobicContact CG2-CE2 3.68Å; I327-F331 WeakPolarHBondContact O-CD2 3.27Å; I327-F331 PolarHBondContact O-N 3.13Å
328	M	82.8	Confident	84.9	Confident	1 Å²	1	34 Å²	34	1%	0.005	16%	0.164	C	C	.	.	H	α-helix	trans	-62.1	-46	173.9	-174.4	176.8	-55.4	0	0	111.7	L102 L105 L154 I157 I271 V272 I275 D325 P326 F330 F331 V332	L102-M328 HydrophobicContact CD2-CG 4.06Å; L102-M328 HydrophobicContact CD2-SD 3.67Å; L105-M328 HydrophobicContact CD2-SD 4.43Å; L154-M328 HydrophobicContact CD2-CE 3.17Å; L154-M328 HydrophobicContact CD2-SD 3.92Å; I157-M328 HydrophobicContact CD1-SD 4.02Å; I271-M328 HydrophobicContact CG2-CE 4.39Å; V272-M328 HydrophobicContact CG2-CE 3.57Å; I275-M328 HydrophobicContact CD1-CE 3.96Å; D325-M328 CarbonylContact O-C 3.59Å; D325-M328 WeakPolarHBondContact O-CA 3.21Å; D325-M328 VanDerWaalsContact O-CB 3.23Å; D325-M328 WeakPolarHBondContact O-CB 3.45Å; D325-M328 PolarHBondContact O-N 3.37Å; P326-M328 VanDerWaalsContact C-N 3.34Å; M328-F330 VanDerWaalsContact C-N 3.28Å; M328-F330 PolarHBondContact O-N 3.48Å; M328-F331 PolarHBondContact O-N 2.72Å; M328-F331 VanDerWaalsContact O-N 3.08Å; M328-V332 HydrophobicContact CG-CG2 3.95Å; M328-V332 WeakPolarHBondContact O-CG2 3.29Å; M328-V332 PolarHBondContact O-N 2.82Å
329	Y	85	Confident	84.2	Confident	0 Å²	0	34.9 Å²	34.9	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-57.9	-42.1	178.5	-54	-31.6	0	0	0	111.6	N81 A84 F88 L102 L105 A106 D325 P326 F331 V332 A333 F336	N81-Y329 VanDerWaalsContact OD1-CE2 3.25Å; N81-Y329 WeakPolarHBondContact OD1-CE2 3.43Å; N81-Y329 PolarHBondContact OD1-OH 3.06Å; A84-Y329 HydrophobicContact CB-CD2 3.27Å; A84-Y329 HydrophobicContact CB-CE2 3.47Å; A84-Y329 VanDerWaalsContact CB-CE2 3.47Å; A84-Y329 HydrophobicContact CB-CG 4.05Å; F88-Y329 HydrophobicContact CE2-CD1 4.14Å; F88-Y329 HydrophobicContact CE2-CE1 4.33Å; F88-Y329 HydrophobicContact CE2-CG 4.44Å; F88-Y329 HydrophobicContact CZ-CD1 4.09Å; F88-Y329 HydrophobicContact CZ-CG 4.39Å; L102-Y329 HydrophobicContact CB-CD1 4.24Å; L102-Y329 HydrophobicContact CB-CE1 4.09Å; L102-Y329 HydrophobicContact CD1-CD1 4.33Å; L102-Y329 HydrophobicContact CD2-CD1 3.82Å; L102-Y329 HydrophobicContact CD2-CE1 3.79Å; L102-Y329 HydrophobicContact CG-CD1 4.35Å; L102-Y329 HydrophobicContact CG-CE1 4.43Å; L105-Y329 HydrophobicContact CD2-CE1 4.4Å; A106-Y329 WeakPolarHBondContact CA-OH 3.22Å; A106-Y329 PolarHBondContact N-OH 3.45Å; D325-Y329 HydrophobicContact CB-CE1 4.37Å; D325-Y329 HydrophobicContact CB-CE2 4.14Å; D325-Y329 WeakPolarHBondContact O-CD2 3.28Å; D325-Y329 PolarHBondContact O-N 3.39Å; P326-Y329 VanDerWaalsContact CA-CD2 3.44Å; P326-Y329 HydrophobicContact CB-CD2 4.36Å; P326-Y329 HydrophobicContact CG-CD2 4.42Å; P326-Y329 HydrophobicContact CG-CE2 4.4Å; P326-Y329 PolarHBondContact O-N 3.03Å; Y329-F331 PolarHBondContact O-N 3.37Å; Y329-V332 PolarHBondContact O-N 2.98Å; Y329-A333 WeakPolarHBondContact O-CA 3.47Å; Y329-A333 WeakPolarHBondContact O-CB 3.27Å; Y329-A333 PolarHBondContact O-N 3.3Å; Y329-F336 HydrophobicContact CD2-CE2 4.25Å; Y329-F336 HydrophobicContact CD2-CZ 4.25Å
330	F	82.3	Confident	83.7	Confident	56 Å²	56	37 Å²	37	25%	0.246	18%	0.182	C	C	.	.	H	α-helix	trans	-56.7	-34.5	177.2	-176.4	-93.5	0	0	0	113.3	P326 I327 M328 F336 R337 L340	P326-F330 PolarHBondContact O-N 3.31Å; I327-F330 PolarHBondContact O-N 3.17Å; M328-F330 VanDerWaalsContact C-N 3.28Å; M328-F330 PolarHBondContact O-N 3.48Å; F330-F336 HydrophobicContact CB-CD1 4.26Å; F330-F336 HydrophobicContact CB-CE1 4.37Å; F330-R337 HydrophobicContact CD1-CG 4.33Å; F330-R337 HydrophobicContact CD2-CB 4.13Å; F330-R337 HydrophobicContact CD2-CG 3.75Å; F330-R337 HydrophobicContact CE1-CG 4.06Å; F330-R337 HydrophobicContact CE2-CB 4.3Å; F330-R337 HydrophobicContact CE2-CG 3.48Å; F330-R337 VanDerWaalsContact CE2-CG 3.48Å; F330-R337 HydrophobicContact CG-CG 4.19Å; F330-R337 HydrophobicContact CZ-CG 3.64Å; F330-R337 WeakPolarHBondContact O-CB 2.73Å; F330-R337 WeakPolarHBondContact O-CD 3.21Å; F330-L340 HydrophobicContact CD2-CB 4.45Å; F330-L340 HydrophobicContact CD2-CD2 3.69Å; F330-L340 HydrophobicContact CE2-CD2 4.18Å
331	F	76.4	Confident	83.2	Confident	51 Å²	51	36.9 Å²	36.9	22%	0.224	19%	0.185	C	C	.	.	H	α-helix	trans	-93.4	-28.3	-178.3	-63.7	-58.6	0	0	0	114.3	K264 R267 I271 I327 M328 Y329	K264-F331 VanDerWaalsContact CE-O 3.23Å; K264-F331 WeakPolarHBondContact CE-O 3.46Å; R267-F331 VanDerWaalsContact CD-CE1 3.48Å; R267-F331 HydrophobicContact CG-CD2 4.41Å; R267-F331 HydrophobicContact CG-CG 4.42Å; R267-F331 VanDerWaalsContact NE-CG 3.3Å; I271-F331 HydrophobicContact CD1-CD2 3.22Å; I271-F331 HydrophobicContact CD1-CE2 3.5Å; I271-F331 VanDerWaalsContact CD1-CE2 3.5Å; I271-F331 HydrophobicContact CD1-CG 4.26Å; I327-F331 HydrophobicContact CG2-CD2 4.17Å; I327-F331 HydrophobicContact CG2-CE2 3.68Å; I327-F331 WeakPolarHBondContact O-CD2 3.27Å; I327-F331 PolarHBondContact O-N 3.13Å; M328-F331 PolarHBondContact O-N 2.72Å; M328-F331 VanDerWaalsContact O-N 3.08Å; Y329-F331 PolarHBondContact O-N 3.37Å
332	V	73.4	Confident	82.7	Confident	8 Å²	8	42 Å²	42	5%	0.048	21%	0.212	C	C	.	.	H	α-helix	trans	-90.3	-43.4	-177.8	-175.9	0	0	0	0	111.3	A98 L102 K264 M268 M328 Y329	A98-V332 HydrophobicContact CB-CG1 4.42Å; L102-V332 HydrophobicContact CD1-CB 3.7Å; L102-V332 HydrophobicContact CD1-CG1 3.49Å; L102-V332 VanDerWaalsContact CD1-CG1 3.49Å; K264-V332 PolarHBondContact NZ-O 3.45Å; M268-V332 HydrophobicContact CG-CG2 3.94Å; M268-V332 HydrophobicContact SD-CG2 3.87Å; M328-V332 HydrophobicContact CG-CG2 3.95Å; M328-V332 WeakPolarHBondContact O-CG2 3.29Å; M328-V332 PolarHBondContact O-N 2.82Å; Y329-V332 PolarHBondContact O-N 2.98Å
333	A	75.8	Confident	82.3	Confident	6 Å²	6	47.6 Å²	47.6	5%	0.05	24%	0.24	C	C	.	.			trans	-100.9	105.6	-173.5	0	0	0	0	0	111.9	F88 Y329 K335 F336 R337	F88-A333 HydrophobicContact CE1-CB 3.51Å; F88-A333 HydrophobicContact CZ-CB 3.86Å; Y329-A333 WeakPolarHBondContact O-CA 3.47Å; Y329-A333 WeakPolarHBondContact O-CB 3.27Å; Y329-A333 PolarHBondContact O-N 3.3Å; A333-K335 VanDerWaalsContact C-N 3.27Å; A333-K335 PolarHBondContact O-N 3.36Å; A333-F336 HydrophobicContact CB-CB 3.83Å; A333-F336 PolarHBondContact O-N 3.22Å; A333-R337 PolarHBondContact O-N 3Å
334	E	74.8	Confident	81.8	Confident	93 Å²	93	53.2 Å²	53.2	44%	0.435	27%	0.268	S	S	.	.	H	α-helix	trans	-61.1	-35.6	-176.6	-63.3	-168.9	159	0	0	112.7	R260 R337 H338	R260-E334 IonicContact CZ-OE1 3.81Å; R260-E334 IonicContact NH2-OE1 2.76Å; R260-E334 PolarHBondContact NH2-OE1 2.97Å; E334-R337 WeakPolarHBondContact O-CB 3.48Å; E334-R337 PolarHBondContact O-N 3.12Å; E334-H338 PolarHBondContact O-CD2 3.44Å; E334-H338 PolarHBondContact O-N 2.64Å
335	K	75.1	Confident	81.3	Confident	110 Å²	110	55.8 Å²	55.8	48%	0.478	29%	0.288	S	S	.	.	H	α-helix	trans	-69.3	-39.5	177.2	-62.4	-155.9	-174.1	179.5	0	113.1	D91 A333 R337 H338 A339	D91-K335 HydrophobicContact CB-CD 3.98Å; D91-K335 VanDerWaalsContact CG-CD 3.46Å; D91-K335 VanDerWaalsContact OD1-CE 3.28Å; D91-K335 WeakPolarHBondContact OD1-CE 3.49Å; D91-K335 IonicContact OD1-NZ 2.7Å; D91-K335 PolarHBondContact OD1-NZ 3.12Å; D91-K335 WeakPolarHBondContact OD2-CD 3.14Å; D91-K335 WeakPolarHBondContact OD2-CE 3.28Å; D91-K335 IonicContact OD2-NZ 3.67Å; D91-K335 PolarHBondContact OD2-NZ 3.42Å; A333-K335 VanDerWaalsContact C-N 3.27Å; A333-K335 PolarHBondContact O-N 3.36Å; K335-R337 VanDerWaalsContact C-N 3.33Å; K335-H338 PolarHBondContact O-N 3.31Å; K335-A339 WeakPolarHBondContact O-CB 3.39Å; K335-A339 PolarHBondContact O-N 2.99Å
336	F	78.2	Confident	80	Confident	4 Å²	4	57.8 Å²	57.8	2%	0.018	31%	0.309	C	S	.	.	H	α-helix	trans	-59.4	-47.3	173	-173.2	-90.4	0	0	0	110.7	L83 A84 L87 P326 Y329 F330 A333 H338 A339 L340	L83-F336 HydrophobicContact CB-CE2 4.47Å; L83-F336 HydrophobicContact CD2-CE2 4.27Å; L83-F336 HydrophobicContact CG-CE2 4.16Å; A84-F336 HydrophobicContact CB-CD2 3.84Å; A84-F336 HydrophobicContact CB-CE2 3.6Å; L87-F336 HydrophobicContact CD1-CB 4.35Å; L87-F336 HydrophobicContact CD1-CD2 3.88Å; L87-F336 HydrophobicContact CD1-CG 4.46Å; P326-F336 HydrophobicContact CB-CZ 4.17Å; P326-F336 WeakPolarHBondContact O-CE1 2.91Å; Y329-F336 HydrophobicContact CD2-CE2 4.25Å; Y329-F336 HydrophobicContact CD2-CZ 4.25Å; F330-F336 HydrophobicContact CB-CD1 4.26Å; F330-F336 HydrophobicContact CB-CE1 4.37Å; A333-F336 HydrophobicContact CB-CB 3.83Å; A333-F336 PolarHBondContact O-N 3.22Å; F336-H338 PolarHBondContact O-N 2.89Å; F336-A339 PolarHBondContact O-N 3.35Å; F336-L340 HydrophobicContact CE1-CD2 4.28Å; F336-L340 WeakPolarHBondContact O-CB 3.35Å; F336-L340 PolarHBondContact O-N 3.21Å
337	R	82.3	Confident	78.7	Confident	74 Å²	74	66.2 Å²	66.2	28%	0.279	34%	0.344	S	S	.	.	H	α-helix	trans	-54.8	-49.9	174.3	-168.3	175.3	56.3	73.9	8.8	112.4	F330 A333 E334 K335 L340 C341	F330-R337 HydrophobicContact CD1-CG 4.33Å; F330-R337 HydrophobicContact CD2-CB 4.13Å; F330-R337 HydrophobicContact CD2-CG 3.75Å; F330-R337 HydrophobicContact CE1-CG 4.06Å; F330-R337 HydrophobicContact CE2-CB 4.3Å; F330-R337 HydrophobicContact CE2-CG 3.48Å; F330-R337 VanDerWaalsContact CE2-CG 3.48Å; F330-R337 HydrophobicContact CG-CG 4.19Å; F330-R337 HydrophobicContact CZ-CG 3.64Å; F330-R337 WeakPolarHBondContact O-CB 2.73Å; F330-R337 WeakPolarHBondContact O-CD 3.21Å; A333-R337 PolarHBondContact O-N 3Å; E334-R337 WeakPolarHBondContact O-CB 3.48Å; E334-R337 PolarHBondContact O-N 3.12Å; K335-R337 VanDerWaalsContact C-N 3.33Å; R337-L340 PolarHBondContact O-N 3.4Å; R337-C341 WeakPolarHBondContact O-CB 3.05Å; R337-C341 PolarHBondContact O-N 3.2Å; R337-C341 PolarHBondContact O-SG 3.11Å
338	H	83.1	Confident	76.8	Confident	95 Å²	95	73.9 Å²	73.9	44%	0.44	37%	0.367	S	S	.	.	H	α-helix	trans	-65	-42.1	-179.9	-81.2	-67.6	0	0	0	112.6	E334 K335 F336 C341 N342	E334-H338 PolarHBondContact O-CD2 3.44Å; E334-H338 PolarHBondContact O-N 2.64Å; K335-H338 PolarHBondContact O-N 3.31Å; F336-H338 PolarHBondContact O-N 2.89Å; H338-C341 PolarHBondContact O-N 3.22Å; H338-N342 WeakPolarHBondContact O-CB 3.09Å; H338-N342 PolarHBondContact O-N 3.48Å; H338-N342 PolarHBondContact O-ND2 3.15Å; H338-N342 PolarHBondContact O-OD1 3.41Å
339	A	82	Confident	75.1	Confident	20 Å²	20	81.8 Å²	81.8	17%	0.165	41%	0.409	C	S	.	.	H	α-helix	trans	-62.9	-45.6	176.5	0	0	0	0	0	111.5	L87 K335 F336 N342 L343	L87-A339 HydrophobicContact CD1-CB 3.45Å; L87-A339 VanDerWaalsContact CD1-CB 3.45Å; L87-A339 HydrophobicContact CD2-CB 4.1Å; L87-A339 HydrophobicContact CG-CB 4.45Å; K335-A339 WeakPolarHBondContact O-CB 3.39Å; K335-A339 PolarHBondContact O-N 2.99Å; F336-A339 PolarHBondContact O-N 3.35Å; A339-N342 PolarHBondContact O-N 3.43Å; A339-L343 WeakPolarHBondContact O-CB 3.19Å; A339-L343 WeakPolarHBondContact O-CG 3.48Å; A339-L343 PolarHBondContact O-N 3.49Å
340	L	82.4	Confident	73.1	Confident	48 Å²	48	91.6 Å²	91.6	25%	0.251	45%	0.451	S	S	.	.	H	α-helix	trans	-64.7	-44.2	178	-168.9	67.5	0	0	0	111.5	F330 F336 R337 N342 L343 L344	F330-L340 HydrophobicContact CD2-CB 4.45Å; F330-L340 HydrophobicContact CD2-CD2 3.69Å; F330-L340 HydrophobicContact CE2-CD2 4.18Å; F336-L340 HydrophobicContact CE1-CD2 4.28Å; F336-L340 WeakPolarHBondContact O-CB 3.35Å; F336-L340 PolarHBondContact O-N 3.21Å; R337-L340 PolarHBondContact O-N 3.4Å; L340-N342 VanDerWaalsContact C-N 3.32Å; L340-N342 PolarHBondContact O-N 2.96Å; L340-L343 PolarHBondContact O-N 2.95Å; L340-L344 HydrophobicContact CD1-CD1 4.1Å; L340-L344 HydrophobicContact CD1-CG 4.28Å; L340-L344 HydrophobicContact CD2-CD1 4.23Å; L340-L344 HydrophobicContact CG-CD1 3.73Å; L340-L344 HydrophobicContact CG-CG 4.25Å; L340-L344 WeakPolarHBondContact O-CB 3.46Å; L340-L344 VanDerWaalsContact O-CG 3.28Å; L340-L344 WeakPolarHBondContact O-CG 3.34Å; L340-L344 PolarHBondContact O-N 3.41Å
341	C	84.1	Confident	71.1	Confident	41 Å²	41	91.5 Å²	91.5	28%	0.277	47%	0.467	S	S	.	.	H	α-helix	trans	-61.1	-39.3	173.4	-71.1	0	0	0	0	112	R337 H338 L344 C345	R337-C341 WeakPolarHBondContact O-CB 3.05Å; R337-C341 PolarHBondContact O-N 3.2Å; R337-C341 PolarHBondContact O-SG 3.11Å; H338-C341 PolarHBondContact O-N 3.22Å; C341-L344 PolarHBondContact O-N 3.35Å; C341-C345 WeakPolarHBondContact O-CA 3.46Å; C341-C345 WeakPolarHBondContact O-CB 3.35Å; C341-C345 PolarHBondContact O-N 3.27Å; C341-C345 PolarHBondContact O-SG 2.99Å; C341-C345 VanDerWaalsContact O-SG 3.37Å
342	N	84.6	Confident	69.4	Low	108 Å²	108	94.9 Å²	94.9	58%	0.578	49%	0.494	S	S	*	.	H	α-helix	trans	-68.5	-34.9	177.7	-70.9	-15.1	0	0	0	112.6	H338 A339 L340	H338-N342 WeakPolarHBondContact O-CB 3.09Å; H338-N342 PolarHBondContact O-N 3.48Å; H338-N342 PolarHBondContact O-ND2 3.15Å; H338-N342 PolarHBondContact O-OD1 3.41Å; A339-N342 PolarHBondContact O-N 3.43Å; L340-N342 VanDerWaalsContact C-N 3.32Å; L340-N342 PolarHBondContact O-N 2.96Å
343	L	82.4	Confident	68	Low	120 Å²	120	100.1 Å²	100.1	63%	0.628	53%	0.528	S	S	*	.	H	α-helix	trans	-70.4	-43.8	175	-74.7	161.9	0	0	0	111.4	L83 A339 L340	L83-L343 HydrophobicContact CD2-CD1 3.9Å; A339-L343 WeakPolarHBondContact O-CB 3.19Å; A339-L343 WeakPolarHBondContact O-CG 3.48Å; A339-L343 PolarHBondContact O-N 3.49Å; L340-L343 PolarHBondContact O-N 2.95Å
344	L	81.7	Confident	66.4	Low	134 Å²	134	105.6 Å²	105.6	70%	0.702	56%	0.563	S	S	*	*	H	α-helix	trans	-80.7	-35.5	-176.6	-67.4	176	0	0	0	113.8	L340 C341 G346	L340-L344 HydrophobicContact CD1-CD1 4.1Å; L340-L344 HydrophobicContact CD1-CG 4.28Å; L340-L344 HydrophobicContact CD2-CD1 4.23Å; L340-L344 HydrophobicContact CG-CD1 3.73Å; L340-L344 HydrophobicContact CG-CG 4.25Å; L340-L344 WeakPolarHBondContact O-CB 3.46Å; L340-L344 VanDerWaalsContact O-CG 3.28Å; L340-L344 WeakPolarHBondContact O-CG 3.34Å; L340-L344 PolarHBondContact O-N 3.41Å; C341-L344 PolarHBondContact O-N 3.35Å; L344-G346 VanDerWaalsContact C-N 3.35Å
345	C	81.7	Confident	64.6	Low	100 Å²	100	106.2 Å²	106.2	68%	0.676	58%	0.578	S	S	*	*	S	Bend	trans	-87.8	-2.2	-177.6	-62.4	0	0	0	0	113.7	C341	C341-C345 WeakPolarHBondContact O-CA 3.46Å; C341-C345 WeakPolarHBondContact O-CB 3.35Å; C341-C345 PolarHBondContact O-N 3.27Å; C341-C345 PolarHBondContact O-SG 2.99Å; C341-C345 VanDerWaalsContact O-SG 3.37Å
346	G	61.6	Low	63	Low	43 Å²	43	111.1 Å²	111.1	44%	0.443	60%	0.599	S	S	.	*			trans	65	145.8	-172.6	0	0	0	0	0	112	L344 R348	L344-G346 VanDerWaalsContact C-N 3.35Å; G346-R348 PolarHBondContact O-N 3.08Å
347	K	57.4	Low	61.1	Low	200 Å²	200	119.6 Å²	119.6	87%	0.87	64%	0.639	S	S	*	*			trans	-60.8	99.6	169	-67.7	178.8	-177.7	176	0	108.2	L349	K347-L349 VanDerWaalsContact C-N 3.32Å; K347-L349 PolarHBondContact O-N 3.25Å
348	R	46.2	Very low	58.9	Low	239 Å²	239	119.2 Å²	119.2	90%	0.902	66%	0.658	S	S	*	*			trans	-61.3	107	151.2	-74.6	-167.7	-162.8	-142	3.9	105.1	G346 K350	G346-R348 PolarHBondContact O-N 3.08Å; R348-K350 PolarHBondContact O-N 3.17Å
349	L	46.3	Very low	56.6	Low	168 Å²	168	124.5 Å²	124.5	88%	0.88	68%	0.68	S	S	*	*			trans	-43.3	110	170.1	-80.4	141.7	0	0	0	107.8	K347 G351	K347-L349 VanDerWaalsContact C-N 3.32Å; K347-L349 PolarHBondContact O-N 3.25Å; L349-G351 PolarHBondContact O-N 3.25Å; L349-G351 VanDerWaalsContact O-N 3.1Å
350	K	44	Very low	54.5	Low	205 Å²	205	130.2 Å²	130.2	89%	0.891	71%	0.713	S	S	*	*			trans	-63.7	111.8	160.9	-83.1	-176.4	173.5	-175.9	0	104.9	R348	R348-K350 PolarHBondContact O-N 3.17Å
351	G	40.7	Very low	52.4	Low	55 Å²	55	135.3 Å²	135.3	57%	0.567	74%	0.74	S	S	*	*	P	Polyproline II helix	trans	-54.5	162.9	168	0	0	0	0	0	110.8	L349	L349-G351 PolarHBondContact O-N 3.25Å; L349-G351 VanDerWaalsContact O-N 3.1Å
352	P	40	Very low	50.2	Low	122 Å²	122	142.5 Å²	142.5	79%	0.792	77%	0.77	S	S	*	*	P	Polyproline II helix	trans	-57	151.2	-176.2	-15.2	27.9	0	0	0	111
353	P	43.2	Very low	48.2	Very low	117 Å²	117	142.5 Å²	142.5	76%	0.76	78%	0.778	S	S	*	*	P	Polyproline II helix	trans	-61.3	143.2	175.9	27.1	-32.1	0	0	0	109.8	S355	P353-S355 PolarHBondContact O-N 3.02Å
354	P	42.3	Very low	46	Very low	122 Å²	122	142.6 Å²	142.6	79%	0.792	79%	0.789	S	S	*	*	P	Polyproline II helix	trans	-60.7	129.4	174.2	24.3	-30.4	0	0	0	109.2	F356	P354-F356 PolarHBondContact O-N 2.73Å
355	S	38	Very low	43.9	Very low	106 Å²	106	144.6 Å²	144.6	74%	0.741	80%	0.8	S	S	*	*	P	Polyproline II helix	trans	-53.9	131.8	170.7	43.3	0	0	0	0	110.1	P353 E357	P353-S355 PolarHBondContact O-N 3.02Å; S355-E357 PolarHBondContact O-N 2.98Å
356	F	40.3	Very low	41.7	Very low	212 Å²	212	145.6 Å²	145.6	93%	0.93	81%	0.808	S	S	*	*			trans	-63.4	95.3	168.4	-118.6	-100.7	0	0	0	108.4	P354	P354-F356 PolarHBondContact O-N 2.73Å
357	E	38.4	Very low	40.7	Very low	182 Å²	182	148.1 Å²	148.1	85%	0.85	82%	0.824	S	S	*	*			trans	-82.8	114.6	157.5	-96	-174.7	153.5	0	0	108	S355 K359	S355-E357 PolarHBondContact O-N 2.98Å; E357-K359 PolarHBondContact O-N 3.21Å
358	G	36.4	Very low	39.8	Very low	67 Å²	67	148 Å²	148	69%	0.691	82%	0.824	S	S	*	*			trans	-61.8	125.9	178.1	0	0	0	0	0	111.3
359	K	35.4	Very low	39.5	Very low	205 Å²	205	142.5 Å²	142.5	89%	0.891	82%	0.822	S	S	*	*			trans	-95.6	104.5	158.1	-86.4	-177.4	173.9	178.7	0	108.3	E357	E357-K359 PolarHBondContact O-N 3.21Å
360	T	37.3	Very low	39.5	Very low	141 Å²	141	142.1 Å²	142.1	87%	0.865	82%	0.816	S	S	*	*			trans	-62.1	138.2	164	-20	0	0	0	0	109.1
361	N	39.1	Very low	39.2	Very low	154 Å²	154	144.1 Å²	144.1	82%	0.824	84%	0.835	S	S	*	*			trans	-57.1	137.8	177.6	-66.2	-34	0	0	0	112.3
362	E	37.6	Very low	39.1	Very low	193 Å²	193	148.6 Å²	148.6	90%	0.902	85%	0.848	S	S	*	*			trans	-131.8	120.4	139.7	-105.2	-158	132.1	0	0	110.2
363	S	41.9	Very low	39	Very low	107 Å²	107	150 Å²	150	75%	0.748	85%	0.851	S	S	*	*			trans	-78.1	133.2	174.1	42.7	0	0	0	0	111.2
364	S	36.2	Very low	38.8	Very low	123 Å²	123	151.8 Å²	151.8	86%	0.86	86%	0.856	S	S	*	*			trans	-148.9	96.1	146.8	33.2	0	0	0	0	109.6
365	L	37.3	Very low	38.6	Very low	175 Å²	175	153.6 Å²	153.6	92%	0.916	86%	0.86	S	S	*	*			trans	-67.9	123.7	162.9	-88.4	140.1	0	0	0	108.6
366	S	37.2	Very low	38.6	Very low	122 Å²	122	156.6 Å²	156.6	85%	0.853	87%	0.867	S	S	*	*			trans	-122.3	106.1	159.2	-179.2	0	0	0	0	107.5
367	A	38.8	Very low	38.5	Very low	95 Å²	95	152.9 Å²	152.9	79%	0.785	86%	0.863	S	S	*	*			trans	-157.6	112.6	158.4	0	0	0	0	0	109.7
368	K	39.5	Very low	38.5	Very low	199 Å²	199	150.8 Å²	150.8	87%	0.865	86%	0.864	S	S	*	*			trans	-42.6	144.9	168.2	-73.3	167.7	161.5	-177.3	0	114.2
369	S	40.2	Very low	38.7	Very low	122 Å²	122	157.2 Å²	157.2	85%	0.853	88%	0.878	S	S	*	*			trans	-146.6	123.2	138.8	-175.7	0	0	0	0	108
370	E	46.5	Very low	39	Very low	161 Å²	161	153.3 Å²	153.3	75%	0.752	88%	0.876	S	S	*	*			trans	-77.5	155.7	170.9	-63.2	-175.2	140.1	0	0	110.7
371	L	36.2	Very low	39.1	Very low	247 Å²	247	154.4 Å²	154.4	100%	1.293	88%	0.877	S	S	*	*			trans	64.2	0	164.7	-86.1	131.1	0	0	0	119.2

Retrieved 371 of 371 residues in 167.1 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).