A0A096N694_PAPAN Loading...

Phosphatidate cytidylyltransferase

Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.

AlphaFold DB (A0A2K6C5F8), UniProt , Accession A0A096N694, Species PAPAN (Papio anubis, Olive baboon), Gene n/a, Length 461 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	35.4	Very low	29.5	Very low	241 Å²	241	169 Å²	169	100%	1.187	86%	0.863	S	S	*	*				0	111.2	0	-68.2	-170.2	-148.5	0	0	106
2	L	29.3	Very low	29.4	Very low	179 Å²	179	160.8 Å²	160.8	94%	0.937	85%	0.852	S	S	*	*			cis	-118.3	160.6	28.8	-97.2	78.5	0	0	0	113.4
3	E	28	Very low	30.2	Very low	154 Å²	154	159.2 Å²	159.2	72%	0.72	86%	0.856	S	S	*	*			trans	-68.4	138.6	-163.9	-68	-169.4	135.9	0	0	117	R5	E3-R5 IonicContact OE2-NH2 3.52Å
4	L	28.6	Very low	30	Very low	177 Å²	177	152.9 Å²	152.9	93%	0.927	85%	0.847	S	S	*	*			trans	-71.2	130.6	147.7	-75.4	150.2	0	0	0	109
5	R	28.6	Very low	29.8	Very low	207 Å²	207	156.1 Å²	156.1	78%	0.781	85%	0.853	S	S	*	*			trans	-127.2	103.8	163.2	-156.7	174.7	-82.5	-157.3	-1.9	111.7	E3	E3-R5 IonicContact OE2-NH2 3.52Å
6	Y	29.1	Very low	29.8	Very low	217 Å²	217	152.4 Å²	152.4	85%	0.851	85%	0.85	S	S	*	*			trans	-59.9	137.7	162.9	-141.2	-103.2	0	0	0	110.5
7	R	28.9	Very low	29.9	Very low	246 Å²	246	151.9 Å²	151.9	93%	0.928	85%	0.851	S	S	*	*			trans	-150	102.4	150.1	-103.8	-171.4	179.9	-178.3	-0.8	109
8	G	25.7	Very low	30	Very low	57 Å²	57	149.6 Å²	149.6	59%	0.588	85%	0.847	S	S	*	*			trans	-88.7	150.8	158.4	0	0	0	0	0	109.9
9	S	26.1	Very low	30.6	Very low	123 Å²	123	148.1 Å²	148.1	86%	0.86	84%	0.843	S	S	*	*			trans	-163.8	108.4	154.8	-73.2	0	0	0	0	108.6
10	C	29.7	Very low	31	Very low	129 Å²	129	146.6 Å²	146.6	87%	0.872	84%	0.839	S	S	*	*			trans	-79.5	159.2	157	-66.2	0	0	0	0	109.3
11	P	34.8	Very low	31.4	Very low	129 Å²	129	145.7 Å²	145.7	84%	0.838	84%	0.839	S	S	*	*			trans	-127.4	145.9	133.8	20.6	-2	0	0	0	112.3
12	G	29.1	Very low	31.5	Very low	71 Å²	71	145.9 Å²	145.9	73%	0.732	83%	0.827	S	S	*	*			trans	-84.6	-163.6	172.4	0	0	0	0	0	113.3
13	P	39.2	Very low	31.5	Very low	140 Å²	140	147.1 Å²	147.1	91%	0.909	83%	0.828	S	S	*	*				-111.3	162.6	-122.1	39	-32.1	0	0	0	115.2
14	G	27	Very low	31.5	Very low	71 Å²	71	143.4 Å²	143.4	73%	0.732	83%	0.83	S	S	*	*			trans	127.8	108.4	156.7	0	0	0	0	0	114.6
15	E	27	Very low	31.4	Very low	201 Å²	201	144.2 Å²	144.2	94%	0.939	83%	0.829	S	S	*	*				165.6	136.4	116.6	-91	-176.7	163.4	0	0	111
16	A	30	Very low	31.3	Very low	97 Å²	97	138.9 Å²	138.9	80%	0.802	83%	0.83	S	S	*	*			trans	-90	133.1	-177.9	0	0	0	0	0	110.7
17	V	31.7	Very low	31.1	Very low	144 Å²	144	133.5 Å²	133.5	87%	0.873	83%	0.83	S	S	*	*			trans	-147.8	134.9	158.4	-177	0	0	0	0	110.3
18	S	31.5	Very low	30.9	Very low	109 Å²	109	125.9 Å²	125.9	76%	0.762	83%	0.828	S	S	*	*			trans	-74.5	169.2	-173.8	-44.2	0	0	0	0	114.8
19	P	41.3	Very low	30.9	Very low	121 Å²	121	126.9 Å²	126.9	79%	0.786	84%	0.838	S	S	*	*			trans	-97.2	168.2	-171.9	38.9	-32.3	0	0	0	113.3
20	P	39.7	Very low	30.9	Very low	118 Å²	118	128.8 Å²	128.8	77%	0.766	84%	0.839	S	S	*	*			trans	-131.5	178	158	45.6	-31.5	0	0	0	111.4
21	P	38.1	Very low	30.8	Very low	128 Å²	128	131.5 Å²	131.5	83%	0.831	84%	0.838	S	S	*	*				-119.4	175.2	-105.1	18.2	7.1	0	0	0	113.8
22	R	37.1	Very low	30.6	Very low	245 Å²	245	134.4 Å²	134.4	93%	0.925	84%	0.841	S	S	*	*			trans	-84.1	139.5	163.7	-83.1	178.5	166.9	171.6	-4.1	110.9
23	E	29.7	Very low	30.5	Very low	206 Å²	206	137.3 Å²	137.3	96%	0.963	84%	0.844	S	S	*	*			trans	-169.3	144.2	153.1	-100.2	171.4	-162.6	0	0	104.9
24	G	28.1	Very low	30.1	Very low	75 Å²	75	140.3 Å²	140.3	77%	0.773	85%	0.846	S	S	*	*			cis	-176.7	177.3	7.2	0	0	0	0	0	108.6
25	E	26.7	Very low	30	Very low	194 Å²	194	142.2 Å²	142.2	91%	0.907	85%	0.849	S	S	*	*			trans	-63.6	162.7	-165.2	-70.7	161.1	122.3	0	0	119.8
26	A	26.1	Very low	30.5	Very low	95 Å²	95	139.8 Å²	139.8	79%	0.785	85%	0.848	S	S	*	*				111	116.8	129.5	0	0	0	0	0	121
27	A	26.2	Very low	30.7	Very low	104 Å²	104	139.6 Å²	139.6	86%	0.86	84%	0.84	S	S	*	*				75.6	113.2	129.3	0	0	0	0	0	122.3
28	G	24	Very low	30.8	Very low	86 Å²	86	139.2 Å²	139.2	89%	0.887	83%	0.834	S	S	*	*				95.6	123.4	118.3	0	0	0	0	0	118.5
29	G	25.5	Very low	30.8	Very low	78 Å²	78	142.9 Å²	142.9	80%	0.804	84%	0.836	S	S	*	*			trans	145.5	96.6	156.5	0	0	0	0	0	114.5
30	D	26	Very low	30.4	Very low	164 Å²	164	145.5 Å²	145.5	88%	0.877	84%	0.838	S	S	*	*			trans	-63.8	132	166.9	-63.9	-47.6	0	0	0	110.9
31	H	28.8	Very low	30.1	Very low	185 Å²	185	145.3 Å²	145.3	86%	0.856	83%	0.834	S	S	*	*			trans	-153.2	112.3	149	-116.9	-52.1	0	0	0	110.1	T33	H31-T33 PolarHBondContact O-N 3.03Å
32	E	29.6	Very low	29.9	Very low	190 Å²	190	145.1 Å²	145.1	89%	0.888	83%	0.826	S	S	*	*			trans	-58.9	127.5	166.3	-69.6	177.3	143.8	0	0	110.2
33	T	26.9	Very low	29.9	Very low	132 Å²	132	138.5 Å²	138.5	81%	0.81	81%	0.808	S	S	*	*			trans	-145.3	119.7	153	13.2	0	0	0	0	108.3	H31 S35	H31-T33 PolarHBondContact O-N 3.03Å; T33-S35 PolarHBondContact O-N 3.27Å
34	E	30.7	Very low	30.3	Very low	203 Å²	203	135 Å²	135	95%	0.949	80%	0.796	S	S	*	*			trans	-54.4	125.4	169.3	-73	174.8	130.7	0	0	110.3
35	S	25.2	Very low	30.7	Very low	112 Å²	112	138.3 Å²	138.3	78%	0.783	80%	0.796	S	S	*	*			trans	-145	114.2	149.4	62.2	0	0	0	0	109.8	T33 S37	T33-S35 PolarHBondContact O-N 3.27Å; S35-S37 PolarHBondContact O-N 3.42Å
36	T	38	Very low	31.2	Very low	149 Å²	149	139.2 Å²	139.2	91%	0.914	79%	0.791	S	S	*	*			trans	-71.1	98.8	167	41.2	0	0	0	0	109.3
37	S	34.7	Very low	32	Very low	93 Å²	93	140.9 Å²	140.9	65%	0.65	78%	0.778	S	S	*	*			trans	-173.9	148.8	157.8	-167.2	0	0	0	0	107.2	S35	S35-S37 PolarHBondContact O-N 3.42Å
38	D	32.5	Very low	32.3	Very low	137 Å²	137	138.2 Å²	138.2	73%	0.733	76%	0.761	S	S	*	*			trans	86.4	66.4	166.1	-45	-17	0	0	0	116.2
39	K	31.2	Very low	33	Very low	185 Å²	185	140.1 Å²	140.1	80%	0.804	75%	0.751	S	S	*	*			trans	-135.5	32.6	157	-93.2	-169.7	-178.8	173.1	0	113
40	E	34.7	Very low	33.9	Very low	177 Å²	177	141 Å²	141	83%	0.827	74%	0.737	S	S	*	*	S	Bend	trans	-100.3	-10.9	171.5	-84.3	-172.2	152.4	0	0	113.8
41	T	33.5	Very low	34.5	Very low	114 Å²	114	141 Å²	141	70%	0.699	74%	0.737	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91.5	-9	-176.6	37.7	0	0	0	0	115.4
42	D	32.8	Very low	34.9	Very low	123 Å²	123	135.6 Å²	135.6	66%	0.658	72%	0.72	S	S	*	*	T	Hydrogen-bonded Turn	trans	-93	-1	-179.4	-97.7	-23.6	0	0	0	114.5
43	I	37.9	Very low	35.4	Very low	107 Å²	107	132.8 Å²	132.8	55%	0.549	70%	0.701	S	S	.	*	T	Hydrogen-bonded Turn	trans	-90.1	-28.2	-176.3	-59.8	179.6	0	0	0	111.7	Y47	I43-Y47 HydrophobicContact CG2-CD2 4.47Å; I43-Y47 WeakPolarHBondContact O-CD2 3.43Å
44	D	37.2	Very low	36.1	Very low	132 Å²	132	131.4 Å²	131.4	71%	0.706	69%	0.693	S	S	*	*	T	Hydrogen-bonded Turn	trans	-79.2	-38.3	-175.4	-114.1	-4.8	0	0	0	113	R46 Y47	D44-R46 PolarHBondContact O-N 3.42Å; D44-Y47 PolarHBondContact O-N 2.94Å; D44-Y47 VanDerWaalsContact O-N 3.08Å
45	D	37.3	Very low	36.8	Very low	145 Å²	145	127.9 Å²	127.9	78%	0.775	68%	0.68	S	S	*	*	T	Hydrogen-bonded Turn	trans	-70.4	-17.8	-178.6	-78.5	-27	0	0	0	113.7
46	R	36.9	Very low	37.6	Very low	212 Å²	212	126.5 Å²	126.5	80%	0.8	67%	0.671	S	S	*	*	T	Hydrogen-bonded Turn	trans	-95.1	-4.8	175.6	-149.9	178	-69.7	-124.5	0.9	113	D44	D44-R46 PolarHBondContact O-N 3.42Å
47	Y	42.4	Very low	38	Very low	130 Å²	130	123.2 Å²	123.2	51%	0.51	65%	0.648	S	S	.	*	T	Hydrogen-bonded Turn	trans	-89	-24	177.4	-104.2	-112.9	0	0	0	113.1	I43 D44 R208	I43-Y47 HydrophobicContact CG2-CD2 4.47Å; I43-Y47 WeakPolarHBondContact O-CD2 3.43Å; D44-Y47 PolarHBondContact O-N 2.94Å; D44-Y47 VanDerWaalsContact O-N 3.08Å; Y47-R208 VanDerWaalsContact CE1-CZ 3.45Å; Y47-R208 VanDerWaalsContact CE1-NE 3.27Å; Y47-R208 PolarHBondContact O-NH2 3.34Å
48	G	32.6	Very low	38.9	Very low	49 Å²	49	121 Å²	121	51%	0.505	63%	0.628	S	S	.	*	G	3₁₀ helix	trans	-75.1	-15.2	-178.1	0	0	0	0	0	116.4	L50	G48-L50 VanDerWaalsContact C-N 3.26Å; G48-L50 PolarHBondContact O-N 3.24Å
49	D	38.3	Very low	39.8	Very low	125 Å²	125	118.2 Å²	118.2	67%	0.668	62%	0.617	S	S	*	*	G	3₁₀ helix	trans	-86	11.3	-171.6	-154	27.9	0	0	0	114.8	S52	D49-S52 PolarHBondContact O-OG 3.46Å; D49-S52 PolarHBondContact OD1-OG 3.37Å
50	L	44.3	Very low	40.7	Very low	97 Å²	97	117.7 Å²	117.7	51%	0.508	62%	0.618	S	S	.	*	G	3₁₀ helix	trans	-115.5	-15.2	173.3	-103.7	128.5	0	0	0	113.8	G48 S52	G48-L50 VanDerWaalsContact C-N 3.26Å; G48-L50 PolarHBondContact O-N 3.24Å; L50-S52 VanDerWaalsContact C-N 3.28Å
51	D	40	Very low	41.7	Very low	164 Å²	164	111 Å²	111	88%	0.877	59%	0.587	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84.2	-6.1	168.9	-92.6	-12.6	0	0	0	112.1	R53	D51-R53 VanDerWaalsContact C-N 3.33Å
52	S	36.6	Very low	42.5	Very low	72 Å²	72	110.7 Å²	110.7	50%	0.503	59%	0.587	S	S	.	*	T	Hydrogen-bonded Turn	trans	-85.3	-1.8	172.6	59.6	0	0	0	0	113.6	D49 L50 T54	D49-S52 PolarHBondContact O-OG 3.46Å; D49-S52 PolarHBondContact OD1-OG 3.37Å; L50-S52 VanDerWaalsContact C-N 3.28Å; S52-T54 PolarHBondContact O-N 3.09Å; S52-T54 VanDerWaalsContact O-N 3.1Å
53	R	40.6	Very low	43.3	Very low	130 Å²	130	109.7 Å²	109.7	49%	0.491	60%	0.596	S	S	.	*			trans	-78.3	98.4	178	-70	-168.9	160.2	-176.1	-5.8	110.6	D51 D57	D51-R53 VanDerWaalsContact C-N 3.33Å; R53-D57 HydrophobicContact CB-CB 4.21Å; R53-D57 WeakPolarHBondContact CB-OD2 2.91Å; R53-D57 WeakPolarHBondContact CD-OD2 3.27Å; R53-D57 WeakPolarHBondContact CG-OD2 3.39Å; R53-D57 IonicContact CZ-OD2 3.93Å; R53-D57 IonicContact NE-OD2 3.23Å; R53-D57 PolarHBondContact NE-OD2 2.8Å
54	T	41.7	Very low	44	Very low	104 Å²	104	106.6 Å²	106.6	64%	0.638	58%	0.584	S	S	*	*			trans	-47.2	149.4	166.2	-27.2	0	0	0	0	110.4	S52 S56 D57	S52-T54 PolarHBondContact O-N 3.09Å; S52-T54 VanDerWaalsContact O-N 3.1Å; T54-S56 PolarHBondContact O-N 3.09Å; T54-S56 PolarHBondContact O-OG 2.86Å; T54-D57 PolarHBondContact O-N 3.02Å; T54-D57 VanDerWaalsContact O-N 3.11Å
55	D	43.7	Very low	44.5	Very low	128 Å²	128	104.7 Å²	104.7	68%	0.684	58%	0.581	S	S	*	*	G	3₁₀ helix	trans	-45.7	-8.2	175.9	-104.7	-29	0	0	0	115.7	D57 K382	D55-D57 VanDerWaalsContact C-N 3.34Å; D55-K382 PolarHBondContact O-NZ 3.01Å
56	S	42.2	Very low	45.5	Very low	83 Å²	83	102.6 Å²	102.6	58%	0.58	57%	0.569	S	S	*	*	G	3₁₀ helix	trans	-69.4	-17.9	173.3	51.3	0	0	0	0	115.4	T54	T54-S56 PolarHBondContact O-N 3.09Å; T54-S56 PolarHBondContact O-OG 2.86Å
57	D	47.8	Very low	46.6	Very low	81 Å²	81	100.5 Å²	100.5	43%	0.433	56%	0.561	S	S	.	*	G	3₁₀ helix	trans	-90.6	-1.9	-171.4	-76	5.1	0	0	0	115.1	R53 T54 D55 P59	R53-D57 HydrophobicContact CB-CB 4.21Å; R53-D57 WeakPolarHBondContact CB-OD2 2.91Å; R53-D57 WeakPolarHBondContact CD-OD2 3.27Å; R53-D57 WeakPolarHBondContact CG-OD2 3.39Å; R53-D57 IonicContact CZ-OD2 3.93Å; R53-D57 IonicContact NE-OD2 3.23Å; R53-D57 PolarHBondContact NE-OD2 2.8Å; T54-D57 PolarHBondContact O-N 3.02Å; T54-D57 VanDerWaalsContact O-N 3.11Å; D55-D57 VanDerWaalsContact C-N 3.34Å; D57-P59 VanDerWaalsContact O-CD 3.28Å; D57-P59 WeakPolarHBondContact O-CD 3.4Å
58	I	52.2	Low	47.7	Very low	46 Å²	46	95 Å²	95	24%	0.236	54%	0.541	C	S	.	.	S	Bend	trans	-78.8	114	167.5	-56.6	175.5	0	0	0	107.5	E60	I58-E60 PolarHBondContact O-N 3.12Å
59	P	52.9	Low	49.6	Very low	78 Å²	78	95.9 Å²	95.9	51%	0.506	54%	0.538	S	S	.	.	P	Polyproline II helix	trans	-57.5	134.2	178.6	-21.4	32.8	0	0	0	110.6	D57 I61	D57-P59 VanDerWaalsContact O-CD 3.28Å; D57-P59 WeakPolarHBondContact O-CD 3.4Å; P59-I61 PolarHBondContact O-N 3.01Å; P59-I61 VanDerWaalsContact O-N 3.09Å
60	E	50	Low	51.1	Low	174 Å²	174	97.8 Å²	97.8	81%	0.813	54%	0.543	S	S	*	.	P	Polyproline II helix	trans	-59.9	116.9	172.5	-77.6	-170.5	163	0	0	109.5	I58 P62	I58-E60 PolarHBondContact O-N 3.12Å; E60-P62 WeakPolarHBondContact O-CD 3.33Å
61	I	54.9	Low	52.4	Low	37 Å²	37	100.2 Å²	100.2	19%	0.19	56%	0.555	C	S	.	*	P	Polyproline II helix	trans	-73.3	119.9	-179.4	-65	165.3	0	0	0	108	P59 A63 V133 I383	P59-I61 PolarHBondContact O-N 3.01Å; P59-I61 VanDerWaalsContact O-N 3.09Å; I61-A63 PolarHBondContact O-N 2.86Å; I61-V133 HydrophobicContact CD1-CG2 3.85Å; I61-I383 HydrophobicContact CB-CG2 4.13Å; I61-I383 HydrophobicContact CD1-CG2 3.4Å; I61-I383 HydrophobicContact CG1-CG2 4.32Å; I61-I383 HydrophobicContact CG2-CG2 4.38Å
62	P	50.2	Low	53.6	Low	108 Å²	108	94.3 Å²	94.3	70%	0.701	52%	0.523	S	S	*	.	P	Polyproline II helix	trans	-61.1	137.5	179.1	21.3	-30.1	0	0	0	110.9	E60 S64	E60-P62 WeakPolarHBondContact O-CD 3.33Å; P62-S64 PolarHBondContact O-N 3.28Å
63	A	50.3	Low	55	Low	101 Å²	101	94 Å²	94	84%	0.835	51%	0.513	S	S	*	.	P	Polyproline II helix	trans	-57.7	131.1	179.1	0	0	0	0	0	110.7	I61	I61-A63 PolarHBondContact O-N 2.86Å
64	S	52.1	Low	56.6	Low	43 Å²	43	96 Å²	96	30%	0.301	53%	0.525	S	S	.	.	P	Polyproline II helix	trans	-64.6	138.8	-178.9	30.5	0	0	0	0	112.4	P62 N388	P62-S64 PolarHBondContact O-N 3.28Å; S64-N388 WeakPolarHBondContact CB-ND2 3.37Å; S64-N388 PolarHBondContact O-ND2 3.4Å; S64-N388 WeakPolarHBondContact OG-CB 3.48Å; S64-N388 PolarHBondContact OG-ND2 3.31Å; S64-N388 PolarHBondContact OG-OD1 3.39Å
65	S	48.5	Very low	58.1	Low	91 Å²	91	95.1 Å²	95.1	64%	0.636	53%	0.528	S	S	*	.	P	Polyproline II helix	trans	-62.5	148.4	-179.8	52	0	0	0	0	113.4	R67	S65-R67 PolarHBondContact O-N 3.38Å
66	D	57.5	Low	59.4	Low	101 Å²	101	89.8 Å²	89.8	54%	0.54	50%	0.5	S	S	.	.			trans	-70.1	108.6	-179.3	170	28.3	0	0	0	112	T68 K73	D66-T68 PolarHBondContact O-N 3.13Å; D66-T68 WeakPolarHBondContact OD1-CB 3.45Å; D66-T68 PolarHBondContact OD1-N 3.38Å; D66-T68 VanDerWaalsContact OD1-N 3.09Å; D66-T68 PolarHBondContact OD1-OG1 2.71Å; D66-K73 VanDerWaalsContact OD2-CE 3.23Å; D66-K73 WeakPolarHBondContact OD2-CE 3.38Å; D66-K73 IonicContact OD2-NZ 2.85Å; D66-K73 PolarHBondContact OD2-NZ 2.94Å
67	R	59.5	Low	60.7	Low	168 Å²	168	90.3 Å²	90.3	63%	0.634	50%	0.503	S	S	*	.			trans	-90.4	18.7	-178.7	-68.2	-175	174.5	-179.2	-3.1	114.8	S65	S65-R67 PolarHBondContact O-N 3.38Å
68	T	66.4	Low	61.9	Low	14 Å²	14	90.3 Å²	90.3	9%	0.086	52%	0.522	C	S	.	.			trans	-60.9	130.9	-180	-54.5	0	0	0	0	111.3	D66 L72 K73 I88	D66-T68 PolarHBondContact O-N 3.13Å; D66-T68 WeakPolarHBondContact OD1-CB 3.45Å; D66-T68 PolarHBondContact OD1-N 3.38Å; D66-T68 VanDerWaalsContact OD1-N 3.09Å; D66-T68 PolarHBondContact OD1-OG1 2.71Å; T68-L72 HydrophobicContact CG2-CB 4.38Å; T68-L72 HydrophobicContact CG2-CD2 4.19Å; T68-K73 HydrophobicContact CG2-CG 4.09Å; T68-K73 VanDerWaalsContact O-CE 3.3Å; T68-K73 WeakPolarHBondContact O-CE 3.5Å; T68-I88 HydrophobicContact CG2-CD1 3.96Å; T68-I88 HydrophobicContact CG2-CG1 4.48Å; T68-I88 HydrophobicContact CG2-CG2 4.37Å
69	P	71.8	Confident	62.9	Low	68 Å²	68	91.5 Å²	91.5	44%	0.442	53%	0.529	S	S	.	.			trans	-55.6	137.2	-178.9	-24.9	32	0	0	0	113	I71 L72 K73	P69-I71 VanDerWaalsContact C-N 3.27Å; P69-I71 PolarHBondContact O-N 3.23Å; P69-L72 HydrophobicContact CB-CB 4.4Å; P69-L72 WeakPolarHBondContact O-CB 3.48Å; P69-L72 PolarHBondContact O-N 3.03Å; P69-K73 PolarHBondContact O-N 3.27Å
70	E	70.4	Confident	64.1	Low	166 Å²	166	91.1 Å²	91.1	78%	0.776	53%	0.528	S	S	*	.	H	α-helix	trans	-61.5	-34.4	-175.8	-68	-171	164.2	0	0	113.3	L72 K73 K74	E70-L72 VanDerWaalsContact C-N 3.28Å; E70-L72 PolarHBondContact O-N 3.36Å; E70-K73 PolarHBondContact O-N 3.2Å; E70-K73 VanDerWaalsContact O-N 3.15Å; E70-K74 WeakPolarHBondContact O-CB 3.35Å; E70-K74 PolarHBondContact O-N 3.44Å
71	I	70.9	Confident	65.1	Low	147 Å²	147	87 Å²	87	75%	0.754	52%	0.519	S	S	*	.	H	α-helix	trans	-58.6	-44.1	175.7	-57.6	165.9	0	0	0	110.2	P69 K74 A75	P69-I71 VanDerWaalsContact C-N 3.27Å; P69-I71 PolarHBondContact O-N 3.23Å; I71-K74 PolarHBondContact O-N 2.95Å; I71-A75 WeakPolarHBondContact O-CB 3.44Å; I71-A75 PolarHBondContact O-N 2.96Å
72	L	64.5	Low	65.9	Low	40 Å²	40	95.4 Å²	95.4	21%	0.209	55%	0.548	C	S	.	.	H	α-helix	trans	-69.6	-38.3	177.9	-142.1	81.1	0	0	0	111	T68 P69 E70 L76 I88	T68-L72 HydrophobicContact CG2-CB 4.38Å; T68-L72 HydrophobicContact CG2-CD2 4.19Å; P69-L72 HydrophobicContact CB-CB 4.4Å; P69-L72 WeakPolarHBondContact O-CB 3.48Å; P69-L72 PolarHBondContact O-N 3.03Å; E70-L72 VanDerWaalsContact C-N 3.28Å; E70-L72 PolarHBondContact O-N 3.36Å; L72-L76 HydrophobicContact CG-CD1 4.19Å; L72-L76 WeakPolarHBondContact O-CB 3.29Å; L72-L76 PolarHBondContact O-N 3.47Å; L72-L76 VanDerWaalsContact O-N 3.13Å; L72-I88 HydrophobicContact CD2-CB 4.22Å; L72-I88 HydrophobicContact CD2-CG1 3.78Å; L72-I88 HydrophobicContact CD2-CG2 3.96Å
73	K	67.4	Low	67.2	Low	67 Å²	67	97.2 Å²	97.2	29%	0.291	54%	0.541	S	S	.	.	H	α-helix	trans	-64.3	-38.6	175.8	-72.1	-172.7	179.3	-173.8	0	112.3	D66 T68 P69 E70 S77 K84	D66-K73 VanDerWaalsContact OD2-CE 3.23Å; D66-K73 WeakPolarHBondContact OD2-CE 3.38Å; D66-K73 IonicContact OD2-NZ 2.85Å; D66-K73 PolarHBondContact OD2-NZ 2.94Å; T68-K73 HydrophobicContact CG2-CG 4.09Å; T68-K73 VanDerWaalsContact O-CE 3.3Å; T68-K73 WeakPolarHBondContact O-CE 3.5Å; P69-K73 PolarHBondContact O-N 3.27Å; E70-K73 PolarHBondContact O-N 3.2Å; E70-K73 VanDerWaalsContact O-N 3.15Å; K73-S77 PolarHBondContact O-N 3.28Å; K73-K84 PolarHBondContact O-NZ 3.08Å
74	K	74.3	Confident	68.5	Low	172 Å²	172	94.7 Å²	94.7	75%	0.748	51%	0.511	S	S	*	.	H	α-helix	trans	-72.5	-44.3	179.2	-168.4	176.5	-177.9	179	0	111.5	E70 I71 L76 S77	E70-K74 WeakPolarHBondContact O-CB 3.35Å; E70-K74 PolarHBondContact O-N 3.44Å; I71-K74 PolarHBondContact O-N 2.95Å; K74-L76 VanDerWaalsContact C-N 3.28Å; K74-L76 PolarHBondContact O-N 3.48Å; K74-S77 WeakPolarHBondContact O-CB 3.33Å; K74-S77 PolarHBondContact O-N 3.31Å; K74-S77 PolarHBondContact O-OG 3.1Å
75	A	72.9	Confident	69.6	Low	84 Å²	84	96.9 Å²	96.9	69%	0.694	52%	0.519	S	S	*	.	H	α-helix	trans	-63.1	-32.8	177.4	0	0	0	0	0	113.1	I71	I71-A75 WeakPolarHBondContact O-CB 3.44Å; I71-A75 PolarHBondContact O-N 2.96Å
76	L	69.8	Low	71.2	Confident	17 Å²	17	100 Å²	100	9%	0.089	52%	0.517	C	S	.	.	T	Hydrogen-bonded Turn	trans	-102.7	20.4	-179.2	-63.4	163.5	0	0	0	113	L72 K74 G78 L79 K84 W87 I88	L72-L76 HydrophobicContact CG-CD1 4.19Å; L72-L76 WeakPolarHBondContact O-CB 3.29Å; L72-L76 PolarHBondContact O-N 3.47Å; L72-L76 VanDerWaalsContact O-N 3.13Å; K74-L76 VanDerWaalsContact C-N 3.28Å; K74-L76 PolarHBondContact O-N 3.48Å; L76-G78 VanDerWaalsContact C-N 3.3Å; L76-G78 PolarHBondContact O-N 3.48Å; L76-L79 HydrophobicContact CD2-CD1 3.54Å; L76-L79 PolarHBondContact O-N 3.46Å; L76-K84 HydrophobicContact CB-CD 4.24Å; L76-K84 HydrophobicContact CB-CG 3.97Å; L76-K84 HydrophobicContact CD1-CG 4.42Å; L76-W87 HydrophobicContact CD1-CB 4.34Å; L76-W87 HydrophobicContact CD2-CB 3.92Å; L76-W87 HydrophobicContact CD2-CG 4.28Å; L76-I88 HydrophobicContact CD1-CD1 4.34Å; L76-I88 HydrophobicContact CD1-CG1 3.59Å
77	S	69.6	Low	72.4	Confident	93 Å²	93	100.7 Å²	100.7	65%	0.65	51%	0.512	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.9	-24.6	-174.9	56.2	0	0	0	0	114.1	K73 K74	K73-S77 PolarHBondContact O-N 3.28Å; K74-S77 WeakPolarHBondContact O-CB 3.33Å; K74-S77 PolarHBondContact O-N 3.31Å; K74-S77 PolarHBondContact O-OG 3.1Å
78	G	73.4	Confident	73.4	Confident	81 Å²	81	92.9 Å²	92.9	84%	0.835	48%	0.483	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.8	-1.4	178.7	0	0	0	0	0	115.9	L76	L76-G78 VanDerWaalsContact C-N 3.3Å; L76-G78 PolarHBondContact O-N 3.48Å
79	L	72.6	Confident	74.1	Confident	72 Å²	72	98.4 Å²	98.4	38%	0.377	50%	0.502	S	S	.	.	S	Bend	trans	-101.8	144.2	-176.6	-77.9	153.4	0	0	0	111.5	L76 W83	L76-L79 HydrophobicContact CD2-CD1 3.54Å; L76-L79 PolarHBondContact O-N 3.46Å; L79-W83 HydrophobicContact CB-CB 4.4Å; L79-W83 HydrophobicContact CD2-CB 3.97Å
80	S	78.9	Confident	74.7	Confident	70 Å²	70	96.5 Å²	96.5	49%	0.49	50%	0.495	S	S	.	.			trans	-59.8	152.2	172.2	66.1	0	0	0	0	111.5	R82 W83 K84	S80-R82 PolarHBondContact O-N 2.7Å; S80-W83 PolarHBondContact O-N 3.37Å; S80-W83 VanDerWaalsContact OG-CD1 3.31Å; S80-K84 PolarHBondContact O-N 2.97Å
81	S	71.6	Confident	75.5	Confident	88 Å²	88	91.5 Å²	91.5	62%	0.615	47%	0.473	S	S	*	.	H	α-helix	trans	-53.8	-33.3	-172.1	58.8	0	0	0	0	114.2	N85	S81-N85 PolarHBondContact O-N 2.94Å; S81-N85 VanDerWaalsContact O-N 3.11Å; S81-N85 PolarHBondContact O-ND2 2.96Å
82	R	71.4	Confident	76.2	Confident	213 Å²	213	86.2 Å²	86.2	80%	0.804	45%	0.446	S	S	*	.	H	α-helix	trans	-66.9	-50.3	176	-70.5	-172.7	172.3	-170.1	-0.9	112.4	S80 K84 N85 W86	S80-R82 PolarHBondContact O-N 2.7Å; R82-K84 VanDerWaalsContact C-N 3.34Å; R82-N85 PolarHBondContact O-N 2.94Å; R82-W86 PolarHBondContact O-N 3.41Å
83	W	77.7	Confident	77.2	Confident	146 Å²	146	86.9 Å²	86.9	55%	0.553	45%	0.452	S	S	*	.	H	α-helix	trans	-68.2	-36.5	179.7	-76.2	97.1	0	0	0	111.7	L79 S80 N85 W86 W87	L79-W83 HydrophobicContact CB-CB 4.4Å; L79-W83 HydrophobicContact CD2-CB 3.97Å; S80-W83 PolarHBondContact O-N 3.37Å; S80-W83 VanDerWaalsContact OG-CD1 3.31Å; W83-N85 PolarHBondContact O-N 3.1Å; W83-W86 PolarHBondContact O-N 2.9Å; W83-W87 WeakPolarHBondContact O-CB 3.47Å; W83-W87 VanDerWaalsContact O-CD1 3.3Å; W83-W87 PolarHBondContact O-N 3.45Å
84	K	76.4	Confident	78.3	Confident	48 Å²	48	89.4 Å²	89.4	21%	0.209	47%	0.468	C	S	.	.	H	α-helix	trans	-57.1	-49.4	171.9	-177.5	166.7	-176	168.4	0	111.4	K73 L76 S80 R82 W86 W87 I88	K73-K84 PolarHBondContact O-NZ 3.08Å; L76-K84 HydrophobicContact CB-CD 4.24Å; L76-K84 HydrophobicContact CB-CG 3.97Å; L76-K84 HydrophobicContact CD1-CG 4.42Å; S80-K84 PolarHBondContact O-N 2.97Å; R82-K84 VanDerWaalsContact C-N 3.34Å; K84-W86 PolarHBondContact O-N 2.99Å; K84-W87 PolarHBondContact O-N 2.89Å; K84-I88 HydrophobicContact CG-CD1 3.65Å; K84-I88 HydrophobicContact CG-CG1 4.41Å; K84-I88 WeakPolarHBondContact O-CB 3.42Å; K84-I88 WeakPolarHBondContact O-CD1 3.33Å; K84-I88 WeakPolarHBondContact O-CG1 3.41Å; K84-I88 PolarHBondContact O-N 3.26Å
85	N	76.6	Confident	79	Confident	89 Å²	89	85.1 Å²	85.1	48%	0.476	46%	0.456	S	S	.	.	H	α-helix	trans	-64.9	-37.5	178.3	-75.5	-16.2	0	0	0	113.4	S81 R82 W83 R89	S81-N85 PolarHBondContact O-N 2.94Å; S81-N85 VanDerWaalsContact O-N 3.11Å; S81-N85 PolarHBondContact O-ND2 2.96Å; R82-N85 PolarHBondContact O-N 2.94Å; W83-N85 PolarHBondContact O-N 3.1Å; N85-R89 WeakPolarHBondContact O-CB 3.44Å; N85-R89 WeakPolarHBondContact O-CD 3.32Å; N85-R89 WeakPolarHBondContact O-CG 3.43Å; N85-R89 PolarHBondContact O-N 3.17Å
86	W	80.6	Confident	79.8	Confident	157 Å²	157	85.2 Å²	85.2	60%	0.595	44%	0.443	S	S	*	.	H	α-helix	trans	-63.9	-47.4	176.1	-174.2	90.3	0	0	0	111.4	R82 W83 K84 R89 G90	R82-W86 PolarHBondContact O-N 3.41Å; W83-W86 PolarHBondContact O-N 2.9Å; K84-W86 PolarHBondContact O-N 2.99Å; W86-R89 PolarHBondContact O-N 3.43Å; W86-G90 PolarHBondContact O-N 3.34Å
87	W	83	Confident	80.8	Confident	114 Å²	114	88.6 Å²	88.6	43%	0.432	46%	0.461	S	S	.	.	H	α-helix	trans	-64.5	-44.3	176.9	-86.9	107.4	0	0	0	113	L76 W83 K84 R89 G90 I91	L76-W87 HydrophobicContact CD1-CB 4.34Å; L76-W87 HydrophobicContact CD2-CB 3.92Å; L76-W87 HydrophobicContact CD2-CG 4.28Å; W83-W87 WeakPolarHBondContact O-CB 3.47Å; W83-W87 VanDerWaalsContact O-CD1 3.3Å; W83-W87 PolarHBondContact O-N 3.45Å; K84-W87 PolarHBondContact O-N 2.89Å; W87-R89 VanDerWaalsContact C-N 3.28Å; W87-R89 PolarHBondContact O-N 3.04Å; W87-G90 PolarHBondContact O-N 3.49Å; W87-I91 HydrophobicContact CE3-CD1 4.1Å; W87-I91 HydrophobicContact CE3-CG1 4.18Å; W87-I91 WeakPolarHBondContact O-CB 3.18Å; W87-I91 VanDerWaalsContact O-CG1 3.3Å; W87-I91 WeakPolarHBondContact O-CG1 3.13Å; W87-I91 PolarHBondContact O-N 3.46Å
88	I	80	Confident	81.9	Confident	5 Å²	5	87.7 Å²	87.7	3%	0.026	46%	0.455	C	S	.	.	H	α-helix	trans	-57.3	-45.9	176.2	-68.7	164.9	0	0	0	110.1	T68 L72 L76 K84 L92	T68-I88 HydrophobicContact CG2-CD1 3.96Å; T68-I88 HydrophobicContact CG2-CG1 4.48Å; T68-I88 HydrophobicContact CG2-CG2 4.37Å; L72-I88 HydrophobicContact CD2-CB 4.22Å; L72-I88 HydrophobicContact CD2-CG1 3.78Å; L72-I88 HydrophobicContact CD2-CG2 3.96Å; L76-I88 HydrophobicContact CD1-CD1 4.34Å; L76-I88 HydrophobicContact CD1-CG1 3.59Å; K84-I88 HydrophobicContact CG-CD1 3.65Å; K84-I88 HydrophobicContact CG-CG1 4.41Å; K84-I88 WeakPolarHBondContact O-CB 3.42Å; K84-I88 WeakPolarHBondContact O-CD1 3.33Å; K84-I88 WeakPolarHBondContact O-CG1 3.41Å; K84-I88 PolarHBondContact O-N 3.26Å; I88-L92 HydrophobicContact CG2-CD1 3.77Å; I88-L92 WeakPolarHBondContact O-CB 3.37Å; I88-L92 WeakPolarHBondContact O-CG 3.39Å; I88-L92 PolarHBondContact O-N 3.01Å; I88-L92 VanDerWaalsContact O-N 3.07Å
89	R	81.4	Confident	82.8	Confident	129 Å²	129	88.3 Å²	88.3	49%	0.487	44%	0.438	S	S	.	.	H	α-helix	trans	-63.3	-50.7	178.3	-72.8	169.4	-173.7	-114.8	-1.7	110.9	N85 W86 W87 I91 L92 T93 G392 H393	N85-R89 WeakPolarHBondContact O-CB 3.44Å; N85-R89 WeakPolarHBondContact O-CD 3.32Å; N85-R89 WeakPolarHBondContact O-CG 3.43Å; N85-R89 PolarHBondContact O-N 3.17Å; W86-R89 PolarHBondContact O-N 3.43Å; W87-R89 VanDerWaalsContact C-N 3.28Å; W87-R89 PolarHBondContact O-N 3.04Å; R89-I91 PolarHBondContact O-N 2.83Å; R89-L92 PolarHBondContact O-N 3.07Å; R89-T93 WeakPolarHBondContact O-CB 3.49Å; R89-T93 PolarHBondContact O-N 3.45Å; R89-T93 PolarHBondContact O-OG1 2.87Å; R89-G392 PolarHBondContact NE-O 2.86Å; R89-G392 PolarHBondContact NH1-O 3.13Å; R89-G392 PolarHBondContact NH2-O 3.37Å; R89-H393 PolarHBondContact O-CE1 3.09Å
90	G	85.5	Confident	83.8	Confident	28 Å²	28	87.5 Å²	87.5	29%	0.289	43%	0.432	S	S	.	.	H	α-helix	trans	-58.6	-47.8	-179.1	0	0	0	0	0	113.4	W86 W87 T93 L94	W86-G90 PolarHBondContact O-N 3.34Å; W87-G90 PolarHBondContact O-N 3.49Å; G90-T93 PolarHBondContact O-N 3.07Å; G90-L94 WeakPolarHBondContact O-CD1 3.39Å; G90-L94 PolarHBondContact O-N 3.02Å
91	I	86.6	Confident	84.5	Confident	62 Å²	62	90.6 Å²	90.6	32%	0.318	44%	0.437	S	S	.	.	H	α-helix	trans	-62.3	-49.6	178.7	-67	166.9	0	0	0	110.2	W87 R89 T93 L94 T95	W87-I91 HydrophobicContact CE3-CD1 4.1Å; W87-I91 HydrophobicContact CE3-CG1 4.18Å; W87-I91 WeakPolarHBondContact O-CB 3.18Å; W87-I91 VanDerWaalsContact O-CG1 3.3Å; W87-I91 WeakPolarHBondContact O-CG1 3.13Å; W87-I91 PolarHBondContact O-N 3.46Å; R89-I91 PolarHBondContact O-N 2.83Å; I91-T93 VanDerWaalsContact C-N 3.31Å; I91-T93 PolarHBondContact O-N 3.38Å; I91-L94 PolarHBondContact O-N 3.11Å; I91-T95 PolarHBondContact O-N 3Å; I91-T95 PolarHBondContact O-OG1 3.4Å
92	L	85.6	Confident	85.7	Confident	35 Å²	35	90.8 Å²	90.8	18%	0.183	43%	0.43	C	S	.	.	H	α-helix	trans	-61.7	-39.2	179.3	-78	169.6	0	0	0	112.1	I88 R89 T95 M96 P391	I88-L92 HydrophobicContact CG2-CD1 3.77Å; I88-L92 WeakPolarHBondContact O-CB 3.37Å; I88-L92 WeakPolarHBondContact O-CG 3.39Å; I88-L92 PolarHBondContact O-N 3.01Å; I88-L92 VanDerWaalsContact O-N 3.07Å; R89-L92 PolarHBondContact O-N 3.07Å; L92-T95 PolarHBondContact O-N 3.45Å; L92-M96 WeakPolarHBondContact O-CB 3.41Å; L92-M96 VanDerWaalsContact O-CG 3.25Å; L92-M96 WeakPolarHBondContact O-CG 3.38Å; L92-M96 PolarHBondContact O-N 3.19Å; L92-P391 HydrophobicContact CD1-CB 3.98Å; L92-P391 HydrophobicContact CD1-CG 4.44Å; L92-P391 VanDerWaalsContact CD1-O 3.24Å; L92-P391 WeakPolarHBondContact CD1-O 3.42Å
93	T	86	Confident	86.8	Confident	55 Å²	55	81.8 Å²	81.8	34%	0.337	40%	0.398	S	S	.	.	H	α-helix	trans	-62.1	-47	175.4	-55.7	0	0	0	0	111.3	R89 G90 I91 T95 M96 I97 H393	R89-T93 WeakPolarHBondContact O-CB 3.49Å; R89-T93 PolarHBondContact O-N 3.45Å; R89-T93 PolarHBondContact O-OG1 2.87Å; G90-T93 PolarHBondContact O-N 3.07Å; I91-T93 VanDerWaalsContact C-N 3.31Å; I91-T93 PolarHBondContact O-N 3.38Å; T93-T95 PolarHBondContact O-N 3.19Å; T93-M96 PolarHBondContact O-N 2.84Å; T93-I97 HydrophobicContact CG2-CD1 3.89Å; T93-I97 VanDerWaalsContact O-CG1 3.31Å; T93-I97 WeakPolarHBondContact O-CG1 3.42Å; T93-I97 PolarHBondContact O-N 2.93Å; T93-H393 PolarHBondContact OG1-NE2 3.5Å; T93-H393 VanDerWaalsContact OG1-NE2 3.11Å
94	L	89.6	Confident	87.5	Confident	120 Å²	120	75.5 Å²	75.5	63%	0.628	38%	0.375	S	S	*	.	H	α-helix	trans	-60.7	-45.7	175.7	-99.7	92	0	0	0	111.4	G90 I91 M96 I97 S98	G90-L94 WeakPolarHBondContact O-CD1 3.39Å; G90-L94 PolarHBondContact O-N 3.02Å; I91-L94 PolarHBondContact O-N 3.11Å; L94-M96 VanDerWaalsContact C-N 3.33Å; L94-M96 PolarHBondContact O-N 3.47Å; L94-I97 PolarHBondContact O-N 3.33Å; L94-S98 WeakPolarHBondContact O-CB 3.26Å; L94-S98 PolarHBondContact O-N 2.81Å; L94-S98 PolarHBondContact O-OG 2.93Å
95	T	89.5	Confident	88.3	Confident	81 Å²	81	82.2 Å²	82.2	50%	0.497	40%	0.4	S	S	.	.	H	α-helix	trans	-59.4	-43.6	178.1	-55.9	0	0	0	0	111.6	I91 L92 T93 L99	I91-T95 PolarHBondContact O-N 3Å; I91-T95 PolarHBondContact O-OG1 3.4Å; L92-T95 PolarHBondContact O-N 3.45Å; T93-T95 PolarHBondContact O-N 3.19Å; T95-L99 VanDerWaalsContact O-CB 3.22Å; T95-L99 WeakPolarHBondContact O-CB 3.21Å; T95-L99 PolarHBondContact O-N 3.37Å
96	M	89.1	Confident	89	Confident	86 Å²	86	83.3 Å²	83.3	42%	0.424	40%	0.404	S	S	.	.	H	α-helix	trans	-63.6	-43.1	177.4	-73.7	177	67.7	0	0	112.1	L92 T93 L94 F100 I390	L92-M96 WeakPolarHBondContact O-CB 3.41Å; L92-M96 VanDerWaalsContact O-CG 3.25Å; L92-M96 WeakPolarHBondContact O-CG 3.38Å; L92-M96 PolarHBondContact O-N 3.19Å; T93-M96 PolarHBondContact O-N 2.84Å; L94-M96 VanDerWaalsContact C-N 3.33Å; L94-M96 PolarHBondContact O-N 3.47Å; M96-F100 WeakPolarHBondContact O-CB 3.12Å; M96-F100 PolarHBondContact O-N 2.76Å; M96-I390 HydrophobicContact CE-CD1 3.98Å; M96-I390 HydrophobicContact SD-CD1 4.28Å; M96-I390 HydrophobicContact SD-CG2 4.24Å
97	I	90.8	Very high	89.4	Confident	88 Å²	88	76.3 Å²	76.3	45%	0.451	38%	0.381	S	S	.	.	H	α-helix	trans	-64.5	-49.1	177.9	-68.7	169.4	0	0	0	110.5	T93 L94 L99 F100 F101	T93-I97 HydrophobicContact CG2-CD1 3.89Å; T93-I97 VanDerWaalsContact O-CG1 3.31Å; T93-I97 WeakPolarHBondContact O-CG1 3.42Å; T93-I97 PolarHBondContact O-N 2.93Å; L94-I97 PolarHBondContact O-N 3.33Å; I97-L99 VanDerWaalsContact C-N 3.34Å; I97-L99 PolarHBondContact O-N 3.22Å; I97-F100 PolarHBondContact O-N 3.46Å; I97-F101 HydrophobicContact CG2-CD2 3.72Å; I97-F101 HydrophobicContact CG2-CE2 3.57Å; I97-F101 VanDerWaalsContact O-CD2 3.27Å; I97-F101 WeakPolarHBondContact O-CD2 3.36Å; I97-F101 PolarHBondContact O-N 3.25Å
98	S	92.8	Very high	89.6	Confident	75 Å²	75	71.3 Å²	71.3	52%	0.524	36%	0.363	S	S	.	.	H	α-helix	trans	-60.8	-42.4	178.4	-64.5	0	0	0	0	112	L94 F100 F101 L102	L94-S98 WeakPolarHBondContact O-CB 3.26Å; L94-S98 PolarHBondContact O-N 2.81Å; L94-S98 PolarHBondContact O-OG 2.93Å; S98-F100 VanDerWaalsContact C-N 3.34Å; S98-F100 PolarHBondContact O-N 3.45Å; S98-F101 PolarHBondContact O-N 2.73Å; S98-L102 WeakPolarHBondContact O-CB 3.27Å; S98-L102 PolarHBondContact O-N 3.19Å
99	L	93.2	Very high	90	Very high	93 Å²	93	75 Å²	75	49%	0.487	38%	0.379	S	S	.	.	H	α-helix	trans	-63.2	-40.5	175.6	-179.9	62.7	0	0	0	111.6	T95 I97 L102 I103	T95-L99 VanDerWaalsContact O-CB 3.22Å; T95-L99 WeakPolarHBondContact O-CB 3.21Å; T95-L99 PolarHBondContact O-N 3.37Å; I97-L99 VanDerWaalsContact C-N 3.34Å; I97-L99 PolarHBondContact O-N 3.22Å; L99-L102 WeakPolarHBondContact O-CB 3.43Å; L99-L102 PolarHBondContact O-N 3.34Å; L99-I103 HydrophobicContact CD1-CD1 4.14Å; L99-I103 HydrophobicContact CD1-CG1 4.31Å; L99-I103 HydrophobicContact CG-CD1 3.92Å; L99-I103 HydrophobicContact CG-CG1 4.49Å; L99-I103 VanDerWaalsContact O-CG1 3.26Å; L99-I103 WeakPolarHBondContact O-CG1 3.26Å; L99-I103 PolarHBondContact O-N 2.86Å
100	F	93.5	Very high	90.4	Very high	56 Å²	56	71.8 Å²	71.8	25%	0.246	37%	0.37	C	S	.	.	H	α-helix	trans	-63.9	-45.2	178.5	-175.6	-120.8	0	0	0	112	M96 I97 S98 L102 I103 I104 L111 L114 F242 L243	M96-F100 WeakPolarHBondContact O-CB 3.12Å; M96-F100 PolarHBondContact O-N 2.76Å; I97-F100 PolarHBondContact O-N 3.46Å; S98-F100 VanDerWaalsContact C-N 3.34Å; S98-F100 PolarHBondContact O-N 3.45Å; F100-L102 VanDerWaalsContact C-N 3.33Å; F100-L102 PolarHBondContact O-N 3.08Å; F100-I103 PolarHBondContact O-N 3.04Å; F100-I104 HydrophobicContact CD1-CD1 3.84Å; F100-I104 HydrophobicContact CE1-CD1 3.56Å; F100-I104 HydrophobicContact CE1-CG1 4.47Å; F100-I104 HydrophobicContact CE2-CD1 4.37Å; F100-I104 HydrophobicContact CE2-CG1 4.46Å; F100-I104 HydrophobicContact CG-CD1 4.38Å; F100-I104 HydrophobicContact CZ-CD1 3.85Å; F100-I104 HydrophobicContact CZ-CG1 4.35Å; F100-I104 WeakPolarHBondContact O-CG1 3.49Å; F100-I104 PolarHBondContact O-N 3.05Å; F100-L111 HydrophobicContact CE2-CD2 4.15Å; F100-L114 HydrophobicContact CD2-CD2 4.04Å; F100-L114 HydrophobicContact CE2-CD2 4.23Å; F100-F242 HydrophobicContact CE2-CE1 4.22Å; F100-F242 HydrophobicContact CZ-CE1 4.11Å; F100-L243 HydrophobicContact CE1-CD2 4.35Å; F100-L243 HydrophobicContact CZ-CD2 3.98Å
101	F	94.3	Very high	90.8	Very high	134 Å²	134	70.4 Å²	70.4	59%	0.588	36%	0.356	S	S	*	.	H	α-helix	trans	-63.9	-37.5	174.4	-78.1	-66.9	0	0	0	112.8	I97 S98 I104 Y105	I97-F101 HydrophobicContact CG2-CD2 3.72Å; I97-F101 HydrophobicContact CG2-CE2 3.57Å; I97-F101 VanDerWaalsContact O-CD2 3.27Å; I97-F101 WeakPolarHBondContact O-CD2 3.36Å; I97-F101 PolarHBondContact O-N 3.25Å; S98-F101 PolarHBondContact O-N 2.73Å; F101-I104 HydrophobicContact CD1-CD1 4.35Å; F101-I104 PolarHBondContact O-N 2.95Å; F101-Y105 WeakPolarHBondContact O-CB 3.35Å; F101-Y105 PolarHBondContact O-N 3.47Å
102	L	95.3	Very high	91.1	Very high	93 Å²	93	68.6 Å²	68.6	49%	0.487	35%	0.346	S	S	.	.	H	α-helix	trans	-61.4	-44.8	173.4	-179.8	66.8	0	0	0	111.3	S98 L99 F100 Y105 M106	S98-L102 WeakPolarHBondContact O-CB 3.27Å; S98-L102 PolarHBondContact O-N 3.19Å; L99-L102 WeakPolarHBondContact O-CB 3.43Å; L99-L102 PolarHBondContact O-N 3.34Å; F100-L102 VanDerWaalsContact C-N 3.33Å; F100-L102 PolarHBondContact O-N 3.08Å; L102-Y105 WeakPolarHBondContact O-CB 3.25Å; L102-Y105 PolarHBondContact O-N 3.41Å; L102-M106 HydrophobicContact CG-SD 4.5Å; L102-M106 WeakPolarHBondContact O-CG 3.34Å; L102-M106 PolarHBondContact O-N 3.11Å
103	I	94.8	Very high	91.4	Very high	23 Å²	23	70.6 Å²	70.6	12%	0.118	36%	0.357	C	S	.	.	H	α-helix	trans	-64.1	-41.8	178.1	-68.9	168.2	0	0	0	110.9	L99 F100 Y105 M106 G107 M110 L111 L114	L99-I103 HydrophobicContact CD1-CD1 4.14Å; L99-I103 HydrophobicContact CD1-CG1 4.31Å; L99-I103 HydrophobicContact CG-CD1 3.92Å; L99-I103 HydrophobicContact CG-CG1 4.49Å; L99-I103 VanDerWaalsContact O-CG1 3.26Å; L99-I103 WeakPolarHBondContact O-CG1 3.26Å; L99-I103 PolarHBondContact O-N 2.86Å; F100-I103 PolarHBondContact O-N 3.04Å; I103-Y105 VanDerWaalsContact C-N 3.28Å; I103-Y105 PolarHBondContact O-N 3.48Å; I103-M106 PolarHBondContact O-N 3.26Å; I103-G107 PolarHBondContact O-N 3.35Å; I103-M110 HydrophobicContact CG2-CB 4.02Å; I103-L111 HydrophobicContact CG2-CD2 3.71Å; I103-L111 HydrophobicContact CG2-CG 4.01Å; I103-L114 HydrophobicContact CD1-CB 4.47Å; I103-L114 HydrophobicContact CD1-CD1 4.08Å; I103-L114 HydrophobicContact CD1-CD2 3.95Å; I103-L114 HydrophobicContact CD1-CG 4.38Å; I103-L114 HydrophobicContact CG2-CB 4.33Å; I103-L114 HydrophobicContact CG2-CD2 4.14Å
104	I	93.6	Very high	91.8	Very high	14 Å²	14	70.4 Å²	70.4	7%	0.072	35%	0.354	C	S	.	.	H	α-helix	trans	-57.6	-45.3	173.6	-68.4	166.8	0	0	0	110	F100 F101 M106 G107 L111 L243 Y303 F304	F100-I104 HydrophobicContact CD1-CD1 3.84Å; F100-I104 HydrophobicContact CE1-CD1 3.56Å; F100-I104 HydrophobicContact CE1-CG1 4.47Å; F100-I104 HydrophobicContact CE2-CD1 4.37Å; F100-I104 HydrophobicContact CE2-CG1 4.46Å; F100-I104 HydrophobicContact CG-CD1 4.38Å; F100-I104 HydrophobicContact CZ-CD1 3.85Å; F100-I104 HydrophobicContact CZ-CG1 4.35Å; F100-I104 WeakPolarHBondContact O-CG1 3.49Å; F100-I104 PolarHBondContact O-N 3.05Å; F101-I104 HydrophobicContact CD1-CD1 4.35Å; F101-I104 PolarHBondContact O-N 2.95Å; I104-M106 VanDerWaalsContact C-N 3.3Å; I104-M106 PolarHBondContact O-N 3.42Å; I104-G107 PolarHBondContact O-N 2.83Å; I104-L111 HydrophobicContact CG1-CD1 4.38Å; I104-L111 HydrophobicContact CG1-CD2 4.07Å; I104-L243 HydrophobicContact CD1-CD1 4.48Å; I104-L243 HydrophobicContact CD1-CD2 3.56Å; I104-L243 HydrophobicContact CG1-CD2 4.02Å; I104-L243 HydrophobicContact CG2-CD1 4.41Å; I104-Y303 PolarHBondContact O-OH 3.01Å; I104-F304 HydrophobicContact CG2-CE1 3.84Å
105	Y	92.3	Very high	92.1	Very high	190 Å²	190	65.3 Å²	65.3	75%	0.745	33%	0.327	S	S	*	.	H	α-helix	trans	-63	-34.5	178.5	175.7	-97.9	0	0	0	113	F101 L102 I103 G107 Y303	F101-Y105 WeakPolarHBondContact O-CB 3.35Å; F101-Y105 PolarHBondContact O-N 3.47Å; L102-Y105 WeakPolarHBondContact O-CB 3.25Å; L102-Y105 PolarHBondContact O-N 3.41Å; I103-Y105 VanDerWaalsContact C-N 3.28Å; I103-Y105 PolarHBondContact O-N 3.48Å; Y105-G107 PolarHBondContact O-N 2.84Å; Y105-Y303 PolarHBondContact O-OH 3.45Å; Y105-Y303 VanDerWaalsContact O-OH 3.08Å
106	M	90.7	Very high	92.3	Very high	112 Å²	112	63.2 Å²	63.2	55%	0.552	31%	0.313	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.9	-6.4	175.2	-61.8	179.4	84.5	0	0	113.6	L102 I103 I104 M110	L102-M106 HydrophobicContact CG-SD 4.5Å; L102-M106 WeakPolarHBondContact O-CG 3.34Å; L102-M106 PolarHBondContact O-N 3.11Å; I103-M106 PolarHBondContact O-N 3.26Å; I104-M106 VanDerWaalsContact C-N 3.3Å; I104-M106 PolarHBondContact O-N 3.42Å; M106-M110 HydrophobicContact CB-CB 3.98Å; M106-M110 HydrophobicContact CB-CG 3.6Å; M106-M110 HydrophobicContact CE-CG 4.39Å; M106-M110 HydrophobicContact CE-SD 4.41Å; M106-M110 HydrophobicContact SD-CG 4.35Å
107	G	89.4	Confident	92.6	Very high	10 Å²	10	61 Å²	61	10%	0.103	31%	0.312	C	S	.	.			trans	95	178.2	170.1	0	0	0	0	0	116.3	I103 I104 Y105 F109 M110 L111 Y303	I103-G107 PolarHBondContact O-N 3.35Å; I104-G107 PolarHBondContact O-N 2.83Å; Y105-G107 PolarHBondContact O-N 2.84Å; G107-F109 VanDerWaalsContact C-N 3.27Å; G107-F109 PolarHBondContact O-N 3.38Å; G107-M110 PolarHBondContact O-N 3.45Å; G107-M110 VanDerWaalsContact O-N 3.11Å; G107-L111 PolarHBondContact O-N 3.29Å; G107-Y303 WeakPolarHBondContact CA-OH 3.39Å; G107-Y303 PolarHBondContact N-OH 3.43Å
108	S	88.3	Confident	92.8	Very high	8 Å²	8	58.2 Å²	58.2	6%	0.056	30%	0.298	C	S	.	.	H	α-helix	trans	-59.8	-32.4	-170.3	-48.7	0	0	0	0	113.9	L111 M112 M239 V308	S108-L111 PolarHBondContact O-N 3.17Å; S108-M112 PolarHBondContact O-N 2.94Å; S108-M239 WeakPolarHBondContact OG-CG 3.42Å; S108-V308 VanDerWaalsContact CB-CG2 3.47Å; S108-V308 WeakPolarHBondContact OG-CG2 3.34Å
109	F	86.9	Confident	92.9	Very high	82 Å²	82	54.7 Å²	54.7	36%	0.36	27%	0.273	S	S	.	.	H	α-helix	trans	-65.3	-41.3	177.7	-178.7	-100.8	0	0	0	112	G107 L111 M112 L113 F317	G107-F109 VanDerWaalsContact C-N 3.27Å; G107-F109 PolarHBondContact O-N 3.38Å; F109-L111 VanDerWaalsContact C-N 3.35Å; F109-M112 HydrophobicContact CD2-CE 3.53Å; F109-M112 HydrophobicContact CE2-CE 3.43Å; F109-M112 VanDerWaalsContact CE2-CE 3.43Å; F109-M112 HydrophobicContact CG-CE 4.49Å; F109-M112 HydrophobicContact CZ-CE 4.32Å; F109-M112 WeakPolarHBondContact O-CB 3.22Å; F109-M112 PolarHBondContact O-N 3.4Å; F109-L113 HydrophobicContact CD1-CD1 4.28Å; F109-L113 HydrophobicContact CE1-CD1 3.71Å; F109-L113 HydrophobicContact CE1-CG 4.19Å; F109-L113 HydrophobicContact CZ-CD1 4.22Å; F109-L113 HydrophobicContact CZ-CD2 4.42Å; F109-L113 HydrophobicContact CZ-CG 4.37Å; F109-L113 PolarHBondContact O-N 3.05Å; F109-F317 HydrophobicContact CB-CD2 4.49Å; F109-F317 HydrophobicContact CD2-CE2 4.3Å
110	M	91.5	Very high	93	Very high	62 Å²	62	52.7 Å²	52.7	31%	0.305	27%	0.265	S	S	.	.	H	α-helix	trans	-69.3	-34.9	175.9	-70.2	-68.6	132.3	0	0	111.8	I103 M106 G107 L113 L114	I103-M110 HydrophobicContact CG2-CB 4.02Å; M106-M110 HydrophobicContact CB-CB 3.98Å; M106-M110 HydrophobicContact CB-CG 3.6Å; M106-M110 HydrophobicContact CE-CG 4.39Å; M106-M110 HydrophobicContact CE-SD 4.41Å; M106-M110 HydrophobicContact SD-CG 4.35Å; G107-M110 PolarHBondContact O-N 3.45Å; G107-M110 VanDerWaalsContact O-N 3.11Å; M110-L113 HydrophobicContact CE-CD1 3.88Å; M110-L113 PolarHBondContact O-N 2.86Å; M110-L113 HydrophobicContact SD-CD1 4.17Å; M110-L114 WeakPolarHBondContact O-CB 3.13Å; M110-L114 PolarHBondContact O-N 3.03Å
111	L	93.1	Very high	93	Very high	0 Å²	0	55.5 Å²	55.5	0%	0	28%	0.276	C	S	.	.	H	α-helix	trans	-63.1	-40	171.2	-74.9	170.2	0	0	0	112.2	F100 I103 I104 G107 S108 F109 L114 V115 L235 M239 F242	F100-L111 HydrophobicContact CE2-CD2 4.15Å; I103-L111 HydrophobicContact CG2-CD2 3.71Å; I103-L111 HydrophobicContact CG2-CG 4.01Å; I104-L111 HydrophobicContact CG1-CD1 4.38Å; I104-L111 HydrophobicContact CG1-CD2 4.07Å; G107-L111 PolarHBondContact O-N 3.29Å; S108-L111 PolarHBondContact O-N 3.17Å; F109-L111 VanDerWaalsContact C-N 3.35Å; L111-L114 HydrophobicContact CD2-CD2 4.4Å; L111-L114 WeakPolarHBondContact O-CB 3.06Å; L111-L114 PolarHBondContact O-N 2.91Å; L111-V115 WeakPolarHBondContact O-CG2 3.31Å; L111-V115 PolarHBondContact O-N 3.41Å; L111-L235 HydrophobicContact CB-CD1 4.19Å; L111-L235 HydrophobicContact CB-CD2 3.78Å; L111-L235 HydrophobicContact CD1-CD1 3.88Å; L111-M239 HydrophobicContact CD1-CG 4.21Å; L111-M239 HydrophobicContact CD1-SD 3.76Å; L111-F242 HydrophobicContact CD1-CE1 4.45Å; L111-F242 HydrophobicContact CD2-CE1 3.87Å; L111-F242 HydrophobicContact CD2-CZ 4.32Å
112	M	92.3	Very high	93	Very high	23 Å²	23	49.1 Å²	49.1	11%	0.113	25%	0.248	C	C	.	.	H	α-helix	trans	-60.2	-47	173.5	-179.7	-168	67.1	0	0	111.2	S108 F109 L114 V115 L116 I232 L235 F236	S108-M112 PolarHBondContact O-N 2.94Å; F109-M112 HydrophobicContact CD2-CE 3.53Å; F109-M112 HydrophobicContact CE2-CE 3.43Å; F109-M112 VanDerWaalsContact CE2-CE 3.43Å; F109-M112 HydrophobicContact CG-CE 4.49Å; F109-M112 HydrophobicContact CZ-CE 4.32Å; F109-M112 WeakPolarHBondContact O-CB 3.22Å; F109-M112 PolarHBondContact O-N 3.4Å; M112-L114 VanDerWaalsContact C-N 3.3Å; M112-L114 PolarHBondContact O-N 3.41Å; M112-V115 PolarHBondContact O-N 3.46Å; M112-L116 HydrophobicContact CG-CD1 4.2Å; M112-L116 WeakPolarHBondContact O-CG 3.4Å; M112-L116 PolarHBondContact O-N 3.08Å; M112-I232 HydrophobicContact CG-CD1 3.72Å; M112-I232 HydrophobicContact CG-CG1 4.01Å; M112-I232 HydrophobicContact CG-CG2 4.06Å; M112-I232 HydrophobicContact SD-CG2 4.45Å; M112-L235 HydrophobicContact CB-CD2 4.36Å; M112-F236 HydrophobicContact CB-CE1 4.49Å; M112-F236 HydrophobicContact CG-CZ 4.33Å; M112-F236 HydrophobicContact SD-CE1 4.43Å; M112-F236 HydrophobicContact SD-CE2 4.42Å; M112-F236 HydrophobicContact SD-CZ 3.61Å
113	L	93.3	Very high	93	Very high	78 Å²	78	44.7 Å²	44.7	41%	0.408	23%	0.225	S	C	.	.	H	α-helix	trans	-61.8	-38.2	176.3	-67	-177	0	0	0	112.2	F109 M110 L116 G117	F109-L113 HydrophobicContact CD1-CD1 4.28Å; F109-L113 HydrophobicContact CE1-CD1 3.71Å; F109-L113 HydrophobicContact CE1-CG 4.19Å; F109-L113 HydrophobicContact CZ-CD1 4.22Å; F109-L113 HydrophobicContact CZ-CD2 4.42Å; F109-L113 HydrophobicContact CZ-CG 4.37Å; F109-L113 PolarHBondContact O-N 3.05Å; M110-L113 HydrophobicContact CE-CD1 3.88Å; M110-L113 PolarHBondContact O-N 2.86Å; M110-L113 HydrophobicContact SD-CD1 4.17Å; L113-L116 HydrophobicContact CD2-CD1 4.44Å; L113-L116 PolarHBondContact O-N 3.2Å; L113-G117 PolarHBondContact O-N 3.34Å
114	L	94.6	Very high	92.9	Very high	50 Å²	50	47.5 Å²	47.5	26%	0.262	24%	0.238	S	C	.	.	H	α-helix	trans	-60.8	-47.7	174	175.2	65.1	0	0	0	111.2	F100 I103 M110 L111 M112 L116 G117 I118	F100-L114 HydrophobicContact CD2-CD2 4.04Å; F100-L114 HydrophobicContact CE2-CD2 4.23Å; I103-L114 HydrophobicContact CD1-CB 4.47Å; I103-L114 HydrophobicContact CD1-CD1 4.08Å; I103-L114 HydrophobicContact CD1-CD2 3.95Å; I103-L114 HydrophobicContact CD1-CG 4.38Å; I103-L114 HydrophobicContact CG2-CB 4.33Å; I103-L114 HydrophobicContact CG2-CD2 4.14Å; M110-L114 WeakPolarHBondContact O-CB 3.13Å; M110-L114 PolarHBondContact O-N 3.03Å; L111-L114 HydrophobicContact CD2-CD2 4.4Å; L111-L114 WeakPolarHBondContact O-CB 3.06Å; L111-L114 PolarHBondContact O-N 2.91Å; M112-L114 VanDerWaalsContact C-N 3.3Å; M112-L114 PolarHBondContact O-N 3.41Å; L114-L116 PolarHBondContact O-N 2.89Å; L114-G117 PolarHBondContact O-N 3.49Å; L114-I118 HydrophobicContact CD1-CD1 3.87Å; L114-I118 HydrophobicContact CD1-CG1 4.29Å; L114-I118 HydrophobicContact CD2-CD1 4.49Å; L114-I118 HydrophobicContact CG-CD1 3.79Å; L114-I118 WeakPolarHBondContact O-CD1 3.38Å; L114-I118 WeakPolarHBondContact O-CG1 3.21Å; L114-I118 PolarHBondContact O-N 3.45Å
115	V	94.9	Very high	92.8	Very high	13 Å²	13	47 Å²	47	8%	0.079	24%	0.235	C	C	.	.	H	α-helix	trans	-61.9	-44	178.9	171.7	0	0	0	0	111.2	L111 M112 G117 I118 Q119 V231 I232 F242	L111-V115 WeakPolarHBondContact O-CG2 3.31Å; L111-V115 PolarHBondContact O-N 3.41Å; M112-V115 PolarHBondContact O-N 3.46Å; V115-G117 PolarHBondContact O-N 2.82Å; V115-I118 PolarHBondContact O-N 3.37Å; V115-Q119 WeakPolarHBondContact O-CB 3.48Å; V115-Q119 PolarHBondContact O-N 3.21Å; V115-V231 HydrophobicContact CG1-CB 4.25Å; V115-V231 HydrophobicContact CG1-CG1 4.02Å; V115-V231 HydrophobicContact CG2-CG1 3.79Å; V115-I232 HydrophobicContact CB-CD1 4.13Å; V115-I232 HydrophobicContact CB-CG1 4.14Å; V115-I232 HydrophobicContact CG1-CD1 3.82Å; V115-I232 HydrophobicContact CG1-CG1 3.88Å; V115-F242 HydrophobicContact CG2-CE2 3.87Å; V115-F242 HydrophobicContact CG2-CZ 4.32Å
116	L	94.6	Very high	92.7	Very high	38 Å²	38	38.4 Å²	38.4	20%	0.199	20%	0.202	C	C	.	.	H	α-helix	trans	-60.6	-43.8	173.9	-74.2	169.2	0	0	0	111.9	M112 L113 L114 Q119 V120 Y158 I232	M112-L116 HydrophobicContact CG-CD1 4.2Å; M112-L116 WeakPolarHBondContact O-CG 3.4Å; M112-L116 PolarHBondContact O-N 3.08Å; L113-L116 HydrophobicContact CD2-CD1 4.44Å; L113-L116 PolarHBondContact O-N 3.2Å; L114-L116 PolarHBondContact O-N 2.89Å; L116-Q119 WeakPolarHBondContact O-CB 3.32Å; L116-Q119 PolarHBondContact O-N 2.64Å; L116-V120 WeakPolarHBondContact O-CG2 3.38Å; L116-V120 PolarHBondContact O-N 3.35Å; L116-Y158 HydrophobicContact CD2-CD1 4.2Å; L116-Y158 HydrophobicContact CD2-CD2 3.85Å; L116-Y158 HydrophobicContact CD2-CE1 3.73Å; L116-Y158 HydrophobicContact CD2-CE2 3.3Å; L116-Y158 HydrophobicContact CD2-CG 4.27Å; L116-Y158 WeakPolarHBondContact CD2-OH 3.43Å; L116-I232 HydrophobicContact CD2-CD1 4.32Å; L116-I232 HydrophobicContact CG-CD1 4.06Å
117	G	95.2	Very high	92.7	Very high	38 Å²	38	33.6 Å²	33.6	39%	0.392	18%	0.178	S	C	.	.	H	α-helix	trans	-61.8	-44.7	176.9	0	0	0	0	0	112.6	L113 L114 V115 V120 K121	L113-G117 PolarHBondContact O-N 3.34Å; L114-G117 PolarHBondContact O-N 3.49Å; V115-G117 PolarHBondContact O-N 2.82Å; G117-V120 PolarHBondContact O-N 3.27Å; G117-K121 WeakPolarHBondContact O-CG 3.49Å; G117-K121 PolarHBondContact O-N 2.88Å; G117-K121 VanDerWaalsContact O-N 3.11Å
118	I	94.1	Very high	92.6	Very high	30 Å²	30	34.8 Å²	34.8	15%	0.154	18%	0.184	C	C	.	.	H	α-helix	trans	-61.6	-46.6	175	-70.8	159.7	0	0	0	110.4	L114 V115 V120 K121 C122 I396 F400	L114-I118 HydrophobicContact CD1-CD1 3.87Å; L114-I118 HydrophobicContact CD1-CG1 4.29Å; L114-I118 HydrophobicContact CD2-CD1 4.49Å; L114-I118 HydrophobicContact CG-CD1 3.79Å; L114-I118 WeakPolarHBondContact O-CD1 3.38Å; L114-I118 WeakPolarHBondContact O-CG1 3.21Å; L114-I118 PolarHBondContact O-N 3.45Å; V115-I118 PolarHBondContact O-N 3.37Å; I118-V120 PolarHBondContact O-N 3.23Å; I118-K121 PolarHBondContact O-N 3.17Å; I118-C122 PolarHBondContact O-N 2.83Å; I118-C122 PolarHBondContact O-SG 3.22Å; I118-C122 VanDerWaalsContact O-SG 3.4Å; I118-I396 HydrophobicContact CG2-CG2 3.88Å; I118-F400 HydrophobicContact CD1-CE1 4.11Å; I118-F400 HydrophobicContact CD1-CE2 3.97Å; I118-F400 HydrophobicContact CD1-CZ 3.48Å; I118-F400 VanDerWaalsContact CD1-CZ 3.48Å; I118-F400 HydrophobicContact CG1-CE2 4.22Å; I118-F400 HydrophobicContact CG1-CZ 4.22Å; I118-F400 HydrophobicContact CG2-CD1 4.27Å; I118-F400 HydrophobicContact CG2-CD2 3.72Å; I118-F400 HydrophobicContact CG2-CE1 4.25Å; I118-F400 HydrophobicContact CG2-CE2 3.7Å; I118-F400 HydrophobicContact CG2-CG 4.04Å; I118-F400 HydrophobicContact CG2-CZ 3.99Å
119	Q	95.5	Very high	92.5	Very high	2 Å²	2	34.8 Å²	34.8	1%	0.009	18%	0.183	C	C	.	.	H	α-helix	trans	-55.6	-52.5	177.6	175.1	-139.4	-60	0	0	111.8	V115 L116 K121 C122 F123 N154 Y158 V225 S228	V115-Q119 WeakPolarHBondContact O-CB 3.48Å; V115-Q119 PolarHBondContact O-N 3.21Å; L116-Q119 WeakPolarHBondContact O-CB 3.32Å; L116-Q119 PolarHBondContact O-N 2.64Å; Q119-K121 PolarHBondContact O-N 3.14Å; Q119-C122 PolarHBondContact O-N 3.24Å; Q119-F123 WeakPolarHBondContact O-CB 3.42Å; Q119-F123 PolarHBondContact O-N 3.22Å; Q119-N154 PolarHBondContact NE2-ND2 2.9Å; Q119-N154 PolarHBondContact NE2-OD1 3.27Å; Q119-N154 PolarHBondContact OE1-OD1 2.81Å; Q119-Y158 PolarHBondContact OE1-OH 2.9Å; Q119-Y158 VanDerWaalsContact OE1-OH 3.04Å; Q119-V225 HydrophobicContact CG-CG2 4.43Å; Q119-S228 WeakPolarHBondContact CG-OG 3.27Å; Q119-S228 PolarHBondContact OE1-OG 3.28Å
120	V	95.6	Very high	92.2	Very high	51 Å²	51	31 Å²	31	31%	0.309	17%	0.167	S	C	.	.	H	α-helix	trans	-59.4	-38.7	-179.9	171.3	0	0	0	0	110.8	L116 G117 I118 H124 W147 L150	L116-V120 WeakPolarHBondContact O-CG2 3.38Å; L116-V120 PolarHBondContact O-N 3.35Å; G117-V120 PolarHBondContact O-N 3.27Å; I118-V120 PolarHBondContact O-N 3.23Å; V120-H124 WeakPolarHBondContact O-CB 3.11Å; V120-H124 PolarHBondContact O-N 2.87Å; V120-W147 HydrophobicContact CG1-CH2 4Å; V120-W147 HydrophobicContact CG1-CZ3 3.9Å; V120-L150 HydrophobicContact CG2-CD2 4.46Å
121	K	93.8	Very high	91.8	Very high	114 Å²	114	32.7 Å²	32.7	50%	0.496	17%	0.171	S	C	.	.	H	α-helix	trans	-69.5	-44.5	176.7	-69.3	-65	-177.9	-176	0	113	G117 I118 Q119 F123 H124 E125 I396	G117-K121 WeakPolarHBondContact O-CG 3.49Å; G117-K121 PolarHBondContact O-N 2.88Å; G117-K121 VanDerWaalsContact O-N 3.11Å; I118-K121 PolarHBondContact O-N 3.17Å; Q119-K121 PolarHBondContact O-N 3.14Å; K121-F123 VanDerWaalsContact C-N 3.35Å; K121-F123 PolarHBondContact O-N 3.1Å; K121-H124 PolarHBondContact O-N 3.03Å; K121-E125 WeakPolarHBondContact O-CG 3.15Å; K121-E125 PolarHBondContact O-N 3.44Å; K121-I396 HydrophobicContact CB-CD1 3.63Å; K121-I396 HydrophobicContact CG-CD1 3.96Å
122	C	93.8	Very high	91.1	Very high	0 Å²	0	37.9 Å²	37.9	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-59	-46.2	174.6	-71.3	0	0	0	0	111.5	I118 Q119 H124 E125 I126 T224 M397 Y404	I118-C122 PolarHBondContact O-N 2.83Å; I118-C122 PolarHBondContact O-SG 3.22Å; I118-C122 VanDerWaalsContact O-SG 3.4Å; Q119-C122 PolarHBondContact O-N 3.24Å; C122-H124 VanDerWaalsContact C-N 3.34Å; C122-H124 PolarHBondContact O-N 3.38Å; C122-E125 PolarHBondContact O-N 3.26Å; C122-I126 WeakPolarHBondContact O-CG1 3.17Å; C122-I126 PolarHBondContact O-N 2.98Å; C122-T224 HydrophobicContact CB-CG2 4.22Å; C122-M397 HydrophobicContact CB-SD 4.39Å; C122-Y404 WeakPolarHBondContact CB-OH 3.44Å; C122-Y404 PolarHBondContact SG-OH 3.02Å; C122-Y404 VanDerWaalsContact SG-OH 3.4Å
123	F	94.7	Very high	90.3	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-57	-48.8	175.8	178	-96	0	0	0	111.1	Q119 K121 E125 I126 I127 S146 L150 T217 T220 L221	Q119-F123 WeakPolarHBondContact O-CB 3.42Å; Q119-F123 PolarHBondContact O-N 3.22Å; K121-F123 VanDerWaalsContact C-N 3.35Å; K121-F123 PolarHBondContact O-N 3.1Å; F123-E125 VanDerWaalsContact C-N 3.35Å; F123-E125 PolarHBondContact O-N 3.43Å; F123-I126 PolarHBondContact O-N 2.91Å; F123-I127 HydrophobicContact CD1-CG1 4.05Å; F123-I127 HydrophobicContact CD2-CG1 4.11Å; F123-I127 HydrophobicContact CE1-CG1 3.67Å; F123-I127 HydrophobicContact CE2-CD1 3.91Å; F123-I127 HydrophobicContact CE2-CG1 3.68Å; F123-I127 HydrophobicContact CG-CG1 4.27Å; F123-I127 HydrophobicContact CZ-CD1 3.92Å; F123-I127 HydrophobicContact CZ-CG1 3.47Å; F123-I127 VanDerWaalsContact CZ-CG1 3.47Å; F123-I127 WeakPolarHBondContact O-CB 3.41Å; F123-I127 VanDerWaalsContact O-CG1 3.31Å; F123-I127 WeakPolarHBondContact O-CG1 3.41Å; F123-I127 PolarHBondContact O-N 3.27Å; F123-S146 WeakPolarHBondContact CZ-O 3.36Å; F123-L150 HydrophobicContact CB-CD1 4.24Å; F123-L150 HydrophobicContact CD1-CB 4.35Å; F123-L150 HydrophobicContact CD1-CD1 3.96Å; F123-L150 HydrophobicContact CD1-CD2 3.66Å; F123-L150 HydrophobicContact CD1-CG 4.2Å; F123-L150 HydrophobicContact CD2-CD1 3.9Å; F123-L150 HydrophobicContact CE1-CB 3.89Å; F123-L150 HydrophobicContact CE1-CD1 4.26Å; F123-L150 HydrophobicContact CE1-CD2 3.95Å; F123-L150 HydrophobicContact CE1-CG 4.25Å; F123-L150 HydrophobicContact CE2-CD1 4.25Å; F123-L150 HydrophobicContact CG-CD1 3.75Å; F123-L150 HydrophobicContact CG-CD2 4.24Å; F123-L150 HydrophobicContact CG-CG 4.49Å; F123-L150 HydrophobicContact CZ-CB 4.02Å; F123-L150 HydrophobicContact CZ-CD1 4.39Å; F123-T217 HydrophobicContact CZ-CG2 4.43Å; F123-T220 HydrophobicContact CD2-CG2 3.56Å; F123-T220 HydrophobicContact CE2-CG2 4.01Å; F123-T220 HydrophobicContact CG-CG2 4.43Å; F123-L221 HydrophobicContact CD2-CD2 3.87Å; F123-L221 HydrophobicContact CD2-CG 4.44Å; F123-L221 HydrophobicContact CE2-CD2 3.42Å; F123-L221 VanDerWaalsContact CE2-CD2 3.42Å; F123-L221 HydrophobicContact CE2-CG 3.76Å; F123-L221 HydrophobicContact CZ-CD2 4.08Å
124	H	92.4	Very high	89.3	Confident	82 Å²	82	36.7 Å²	36.7	38%	0.38	18%	0.181	S	C	.	.	H	α-helix	trans	-59.2	-42.6	177.1	172	-96	0	0	0	112.6	V120 K121 C122 T128 W147	V120-H124 WeakPolarHBondContact O-CB 3.11Å; V120-H124 PolarHBondContact O-N 2.87Å; K121-H124 PolarHBondContact O-N 3.03Å; C122-H124 VanDerWaalsContact C-N 3.34Å; C122-H124 PolarHBondContact O-N 3.38Å; H124-T128 WeakPolarHBondContact O-CB 3.3Å; H124-T128 PolarHBondContact O-N 3.29Å; H124-T128 PolarHBondContact O-OG1 3.47Å; H124-W147 HydrophobicContact CB-CH2 4.18Å; H124-W147 HydrophobicContact CB-CZ2 4.2Å; H124-W147 AromaticContact CD2-CZ2 3.78Å
125	E	91.5	Very high	88	Confident	4 Å²	4	39.1 Å²	39.1	2%	0.019	19%	0.191	C	C	.	.	H	α-helix	trans	-61	-48.3	177.4	-70.6	-179.7	179.5	0	0	111.7	K121 C122 F123 T128 I129 A387 T389 I396 M397	K121-E125 WeakPolarHBondContact O-CG 3.15Å; K121-E125 PolarHBondContact O-N 3.44Å; C122-E125 PolarHBondContact O-N 3.26Å; F123-E125 VanDerWaalsContact C-N 3.35Å; F123-E125 PolarHBondContact O-N 3.43Å; E125-T128 PolarHBondContact O-N 2.85Å; E125-I129 WeakPolarHBondContact O-CG1 3.13Å; E125-I129 PolarHBondContact O-N 3.49Å; E125-A387 HydrophobicContact CB-CB 4.29Å; E125-A387 HydrophobicContact CG-CB 3.62Å; E125-T389 WeakPolarHBondContact OE1-CB 3.2Å; E125-T389 PolarHBondContact OE1-OG1 3.3Å; E125-I396 VanDerWaalsContact CD-N 3.34Å; E125-I396 PolarHBondContact OE1-N 3.44Å; E125-I396 PolarHBondContact OE2-N 2.97Å; E125-M397 PolarHBondContact OE2-N 2.92Å
126	I	89.9	Confident	86.3	Confident	10 Å²	10	42.6 Å²	42.6	5%	0.051	22%	0.216	C	C	.	.	H	α-helix	trans	-67.4	-45.1	-178.6	-62.1	166.9	0	0	0	111.7	C122 F123 T128 I129 G130 W216 T220 T224 F386 M397	C122-I126 WeakPolarHBondContact O-CG1 3.17Å; C122-I126 PolarHBondContact O-N 2.98Å; F123-I126 PolarHBondContact O-N 2.91Å; I126-T128 VanDerWaalsContact C-N 3.3Å; I126-T128 PolarHBondContact O-N 3.4Å; I126-I129 PolarHBondContact O-N 3.33Å; I126-G130 PolarHBondContact O-N 3.28Å; I126-W216 HydrophobicContact CG2-CZ2 4.03Å; I126-W216 PolarHBondContact O-NE1 2.92Å; I126-W216 VanDerWaalsContact O-NE1 3.15Å; I126-T220 HydrophobicContact CB-CG2 3.77Å; I126-T220 HydrophobicContact CD1-CG2 3.93Å; I126-T220 HydrophobicContact CG1-CG2 4.48Å; I126-T220 HydrophobicContact CG2-CG2 3.68Å; I126-T220 WeakPolarHBondContact CG2-OG1 3.33Å; I126-T224 HydrophobicContact CD1-CG2 3.95Å; I126-F386 HydrophobicContact CG1-CD1 4.21Å; I126-F386 HydrophobicContact CG1-CE1 4.32Å; I126-M397 HydrophobicContact CD1-CE 3.83Å; I126-M397 HydrophobicContact CD1-CG 4.2Å; I126-M397 HydrophobicContact CD1-SD 3.84Å; I126-M397 HydrophobicContact CG1-CG 4.24Å
127	I	90.6	Very high	84.7	Confident	10 Å²	10	45.1 Å²	45.1	5%	0.051	22%	0.224	C	C	.	.	H	α-helix	trans	-63.9	-37.3	177.2	-65.4	-56.2	0	0	0	111.2	F123 I129 G130 Y131 F142 T220	F123-I127 HydrophobicContact CD1-CG1 4.05Å; F123-I127 HydrophobicContact CD2-CG1 4.11Å; F123-I127 HydrophobicContact CE1-CG1 3.67Å; F123-I127 HydrophobicContact CE2-CD1 3.91Å; F123-I127 HydrophobicContact CE2-CG1 3.68Å; F123-I127 HydrophobicContact CG-CG1 4.27Å; F123-I127 HydrophobicContact CZ-CD1 3.92Å; F123-I127 HydrophobicContact CZ-CG1 3.47Å; F123-I127 VanDerWaalsContact CZ-CG1 3.47Å; F123-I127 WeakPolarHBondContact O-CB 3.41Å; F123-I127 VanDerWaalsContact O-CG1 3.31Å; F123-I127 WeakPolarHBondContact O-CG1 3.41Å; F123-I127 PolarHBondContact O-N 3.27Å; I127-I129 VanDerWaalsContact C-N 3.31Å; I127-I129 PolarHBondContact O-N 3.05Å; I127-G130 PolarHBondContact O-N 3.08Å; I127-Y131 PolarHBondContact O-N 3.01Å; I127-F142 HydrophobicContact CG2-CE1 4.43Å; I127-T220 HydrophobicContact CD1-CG2 4.31Å; I127-T220 HydrophobicContact CG1-CG2 4.49Å
128	T	88.3	Confident	83.1	Confident	36 Å²	36	49.9 Å²	49.9	22%	0.221	24%	0.24	C	C	.	.	H	α-helix	trans	-64.2	-35.9	178	-61.6	0	0	0	0	111.9	H124 E125 I126 Y131 R132	H124-T128 WeakPolarHBondContact O-CB 3.3Å; H124-T128 PolarHBondContact O-N 3.29Å; H124-T128 PolarHBondContact O-OG1 3.47Å; E125-T128 PolarHBondContact O-N 2.85Å; I126-T128 VanDerWaalsContact C-N 3.3Å; I126-T128 PolarHBondContact O-N 3.4Å; T128-Y131 PolarHBondContact O-N 3.04Å; T128-R132 WeakPolarHBondContact O-CG 3.14Å; T128-R132 PolarHBondContact O-N 3.48Å
129	I	85.3	Confident	81.8	Confident	8 Å²	8	49.7 Å²	49.7	4%	0.041	24%	0.24	C	C	.	.	H	α-helix	trans	-64	-50.2	174.3	-66.1	161.7	0	0	0	110.2	E125 I126 I127 Y131 R132 V133 W216 I383 F386	E125-I129 WeakPolarHBondContact O-CG1 3.13Å; E125-I129 PolarHBondContact O-N 3.49Å; I126-I129 PolarHBondContact O-N 3.33Å; I127-I129 VanDerWaalsContact C-N 3.31Å; I127-I129 PolarHBondContact O-N 3.05Å; I129-Y131 PolarHBondContact O-N 2.94Å; I129-R132 PolarHBondContact O-N 3.03Å; I129-V133 HydrophobicContact CG2-CG2 4.27Å; I129-V133 WeakPolarHBondContact O-CG2 3.27Å; I129-V133 PolarHBondContact O-N 2.96Å; I129-W216 HydrophobicContact CG2-CZ2 4.5Å; I129-I383 HydrophobicContact CD1-CD1 3.77Å; I129-I383 HydrophobicContact CG1-CD1 4.3Å; I129-I383 HydrophobicContact CG2-CD1 4.1Å; I129-F386 HydrophobicContact CD1-CB 3.99Å; I129-F386 HydrophobicContact CD1-CD1 3.38Å; I129-F386 HydrophobicContact CD1-CE1 4.25Å; I129-F386 HydrophobicContact CD1-CG 4.05Å; I129-F386 WeakPolarHBondContact CD1-O 3.38Å
130	G	82.3	Confident	80.2	Confident	2 Å²	2	53.4 Å²	53.4	2%	0.021	26%	0.264	C	S	.	.	H	α-helix	trans	-54.1	-45.5	176.7	0	0	0	0	0	111.2	I126 I127 R132 V133 Y134	I126-G130 PolarHBondContact O-N 3.28Å; I127-G130 PolarHBondContact O-N 3.08Å; G130-R132 PolarHBondContact O-N 3.35Å; G130-V133 PolarHBondContact O-N 2.82Å; G130-Y134 WeakPolarHBondContact O-CD2 3.24Å; G130-Y134 PolarHBondContact O-N 3.39Å; G130-Y134 VanDerWaalsContact O-N 3.16Å
131	Y	81.4	Confident	79.1	Confident	97 Å²	97	59.6 Å²	59.6	38%	0.38	28%	0.281	S	S	.	.	H	α-helix	trans	-61.3	-42.4	176.3	-179.9	-107.5	0	0	0	113.5	I127 T128 I129 Y134 H135 F142	I127-Y131 PolarHBondContact O-N 3.01Å; T128-Y131 PolarHBondContact O-N 3.04Å; I129-Y131 PolarHBondContact O-N 2.94Å; Y131-Y134 CarbonylContact O-C 3.46Å; Y131-Y134 PolarHBondContact O-N 3.47Å; Y131-H135 AromaticContact CE1-CD2 3.48Å; Y131-H135 VanDerWaalsContact CE1-CD2 3.48Å; Y131-H135 WeakPolarHBondContact CE1-CD2 3.44Å; Y131-H135 AromaticContact CZ-CD2 3.68Å; Y131-H135 VanDerWaalsContact O-CA 3.31Å; Y131-H135 WeakPolarHBondContact O-CA 3.42Å; Y131-H135 WeakPolarHBondContact O-CB 3.48Å; Y131-H135 PolarHBondContact O-N 2.7Å; Y131-F142 HydrophobicContact CD2-CD1 4.44Å
132	R	80	Confident	78.4	Confident	109 Å²	109	55.2 Å²	55.2	41%	0.411	26%	0.262	S	S	.	.	H	α-helix	trans	-65.6	-40	178.4	-75.3	179.5	-175.8	-177.9	2.8	112.7	T128 I129 G130 Y134	T128-R132 WeakPolarHBondContact O-CG 3.14Å; T128-R132 PolarHBondContact O-N 3.48Å; I129-R132 PolarHBondContact O-N 3.03Å; G130-R132 PolarHBondContact O-N 3.35Å; R132-Y134 PolarHBondContact O-N 3.17Å
133	V	75.4	Confident	77.9	Confident	17 Å²	17	63.7 Å²	63.7	10%	0.103	29%	0.294	C	S	.	.	H	α-helix	trans	-62.8	-35.7	177.7	173.3	0	0	0	0	110.8	I61 I129 G130 F381	I61-V133 HydrophobicContact CD1-CG2 3.85Å; I129-V133 HydrophobicContact CG2-CG2 4.27Å; I129-V133 WeakPolarHBondContact O-CG2 3.27Å; I129-V133 PolarHBondContact O-N 2.96Å; G130-V133 PolarHBondContact O-N 2.82Å; V133-F381 HydrophobicContact CG1-CD1 4.41Å; V133-F381 HydrophobicContact CG1-CE1 4.49Å; V133-F381 HydrophobicContact CG2-CD1 3.89Å; V133-F381 HydrophobicContact CG2-CE1 4.5Å
134	Y	71.9	Confident	77.7	Confident	59 Å²	59	67.4 Å²	67.4	23%	0.231	32%	0.318	C	S	.	.	T	Hydrogen-bonded Turn	trans	-110.3	18.6	-174	-61	-61.7	0	0	0	114.1	G130 Y131 R132 S136 L209 M213	G130-Y134 WeakPolarHBondContact O-CD2 3.24Å; G130-Y134 PolarHBondContact O-N 3.39Å; G130-Y134 VanDerWaalsContact O-N 3.16Å; Y131-Y134 CarbonylContact O-C 3.46Å; Y131-Y134 PolarHBondContact O-N 3.47Å; R132-Y134 PolarHBondContact O-N 3.17Å; Y134-S136 PolarHBondContact O-N 3.44Å; Y134-S136 VanDerWaalsContact O-N 3.15Å; Y134-L209 HydrophobicContact CD1-CD1 3.18Å; Y134-L209 HydrophobicContact CD2-CD1 4.2Å; Y134-L209 HydrophobicContact CE1-CD1 3.67Å; Y134-L209 HydrophobicContact CG-CD1 3.49Å; Y134-L209 VanDerWaalsContact CG-CD1 3.49Å; Y134-M213 HydrophobicContact CD2-CE 4.13Å; Y134-M213 HydrophobicContact CD2-CG 4.39Å; Y134-M213 HydrophobicContact CG-CE 3.94Å
135	H	66.7	Low	77.6	Confident	101 Å²	101	64.4 Å²	64.4	47%	0.468	30%	0.304	S	S	.	.	G	3₁₀ helix	trans	-62.4	-23.6	-172.9	-175.1	-75.4	0	0	0	113.4	Y131 Y137	Y131-H135 AromaticContact CE1-CD2 3.48Å; Y131-H135 VanDerWaalsContact CE1-CD2 3.48Å; Y131-H135 WeakPolarHBondContact CE1-CD2 3.44Å; Y131-H135 AromaticContact CZ-CD2 3.68Å; Y131-H135 VanDerWaalsContact O-CA 3.31Å; Y131-H135 WeakPolarHBondContact O-CA 3.42Å; Y131-H135 WeakPolarHBondContact O-CB 3.48Å; Y131-H135 PolarHBondContact O-N 2.7Å; H135-Y137 PolarHBondContact O-N 2.87Å
136	S	58.7	Low	77.7	Confident	87 Å²	87	64.3 Å²	64.3	61%	0.608	30%	0.304	S	S	*	.	G	3₁₀ helix	trans	-66.6	-3.4	-173.3	53.5	0	0	0	0	115.5	Y134	Y134-S136 PolarHBondContact O-N 3.44Å; Y134-S136 VanDerWaalsContact O-N 3.15Å
137	Y	61.8	Low	78	Confident	91 Å²	91	68.4 Å²	68.4	36%	0.357	32%	0.319	S	S	.	.	G	3₁₀ helix	trans	-116.7	8.9	-168.1	-64.7	-74.4	0	0	0	115.5	H135 L139 H206 L209	H135-Y137 PolarHBondContact O-N 2.87Å; Y137-L139 PolarHBondContact O-N 3.39Å; Y137-H206 AromaticContact CD1-CE1 3.53Å; Y137-H206 AromaticContact CD1-ND1 3.67Å; Y137-L209 HydrophobicContact CD1-CD2 4.4Å; Y137-L209 HydrophobicContact CD2-CD2 3.27Å; Y137-L209 HydrophobicContact CE2-CD2 4.03Å; Y137-L209 HydrophobicContact CG-CD2 3.48Å; Y137-L209 VanDerWaalsContact CG-CD2 3.48Å
138	D	61.3	Low	78.3	Confident	137 Å²	137	70.7 Å²	70.7	73%	0.733	33%	0.327	S	S	*	.			trans	33.8	54	175.6	-83.1	-26	0	0	0	114	P140	D138-P140 WeakPolarHBondContact O-CD 3.49Å
139	L	67.1	Low	78.7	Confident	27 Å²	27	69 Å²	69	14%	0.141	32%	0.317	C	S	.	.			trans	-78.9	113.7	179.8	-69.6	171.1	0	0	0	109.5	Y137 H206 L209 Q210 M213	Y137-L139 PolarHBondContact O-N 3.39Å; L139-H206 HydrophobicContact CD2-CB 3.98Å; L139-L209 HydrophobicContact CD1-CD2 3.71Å; L139-L209 HydrophobicContact CD1-CG 3.93Å; L139-Q210 HydrophobicContact CD1-CG 4.06Å; L139-Q210 HydrophobicContact CD2-CG 4.04Å; L139-M213 HydrophobicContact CD1-CE 3.78Å; L139-M213 HydrophobicContact CD1-SD 3.59Å; L139-M213 VanDerWaalsContact CD1-SD 3.59Å
140	P	62.3	Low	79.3	Confident	79 Å²	79	69 Å²	69	51%	0.513	32%	0.317	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.4	150.4	176.3	30.4	-34.4	0	0	0	109.7	D138 F142	D138-P140 WeakPolarHBondContact O-CD 3.49Å; P140-F142 VanDerWaalsContact C-N 3.32Å; P140-F142 PolarHBondContact O-N 3.33Å; P140-F142 VanDerWaalsContact O-N 3.14Å
141	W	71.7	Confident	79.9	Confident	181 Å²	181	74.3 Å²	74.3	69%	0.686	34%	0.344	S	S	*	.	T	Hydrogen-bonded Turn	trans	72.3	-12.5	172.7	-55.9	97.1	0	0	0	119.4	R143 T144 L145	W141-R143 VanDerWaalsContact C-N 3.3Å; W141-R143 PolarHBondContact O-N 3.12Å; W141-T144 HydrophobicContact CE3-CG2 4.1Å; W141-T144 HydrophobicContact CZ3-CG2 4.25Å; W141-T144 PolarHBondContact O-N 3.25Å; W141-T144 VanDerWaalsContact O-N 3.12Å; W141-L145 WeakPolarHBondContact O-CB 3.47Å; W141-L145 PolarHBondContact O-N 3.09Å
142	F	78.3	Confident	80.7	Confident	22 Å²	22	70 Å²	70	10%	0.096	33%	0.328	C	S	.	.	H	α-helix	trans	-54.2	-44.4	-177.7	172.8	-114.4	0	0	0	113.6	I127 Y131 P140 L145 S146 M213	I127-F142 HydrophobicContact CG2-CE1 4.43Å; Y131-F142 HydrophobicContact CD2-CD1 4.44Å; P140-F142 VanDerWaalsContact C-N 3.32Å; P140-F142 PolarHBondContact O-N 3.33Å; P140-F142 VanDerWaalsContact O-N 3.14Å; F142-L145 PolarHBondContact O-N 3.02Å; F142-S146 VanDerWaalsContact CE2-OG 3.29Å; F142-S146 WeakPolarHBondContact CE2-OG 3.24Å; F142-S146 WeakPolarHBondContact O-CB 3.46Å; F142-S146 PolarHBondContact O-N 3.32Å; F142-S146 PolarHBondContact O-OG 2.9Å; F142-M213 HydrophobicContact CB-SD 4.25Å; F142-M213 HydrophobicContact CD1-CE 4.49Å; F142-M213 HydrophobicContact CD1-SD 3.77Å; F142-M213 HydrophobicContact CD2-CB 3.8Å; F142-M213 HydrophobicContact CD2-CG 4.24Å; F142-M213 HydrophobicContact CD2-SD 3.76Å; F142-M213 HydrophobicContact CE1-CG 4.31Å; F142-M213 HydrophobicContact CE1-SD 4.04Å; F142-M213 HydrophobicContact CE2-CB 3.43Å; F142-M213 VanDerWaalsContact CE2-CB 3.43Å; F142-M213 HydrophobicContact CE2-CG 3.98Å; F142-M213 HydrophobicContact CE2-SD 4.08Å; F142-M213 HydrophobicContact CG-SD 3.61Å; F142-M213 HydrophobicContact CZ-CB 3.87Å; F142-M213 HydrophobicContact CZ-CG 3.98Å; F142-M213 HydrophobicContact CZ-SD 4.18Å
143	R	84.6	Confident	81.5	Confident	178 Å²	178	66 Å²	66	67%	0.672	32%	0.316	S	S	*	.	H	α-helix	trans	-63	-49.6	178.4	-173.2	175.4	70.2	-171.1	0.2	111.1	W141 L145 S146 W147	W141-R143 VanDerWaalsContact C-N 3.3Å; W141-R143 PolarHBondContact O-N 3.12Å; R143-L145 VanDerWaalsContact C-N 3.31Å; R143-L145 PolarHBondContact O-N 3.29Å; R143-S146 PolarHBondContact O-N 2.86Å; R143-W147 PolarHBondContact O-N 2.81Å
144	T	89.4	Confident	82.4	Confident	79 Å²	79	66.4 Å²	66.4	49%	0.485	32%	0.317	S	S	.	.	H	α-helix	trans	-60	-44.2	-179.6	-51	0	0	0	0	111	W141 S146 W147 Y148	W141-T144 HydrophobicContact CE3-CG2 4.1Å; W141-T144 HydrophobicContact CZ3-CG2 4.25Å; W141-T144 PolarHBondContact O-N 3.25Å; W141-T144 VanDerWaalsContact O-N 3.12Å; T144-S146 PolarHBondContact O-N 3.13Å; T144-W147 PolarHBondContact O-N 2.96Å; T144-Y148 WeakPolarHBondContact O-CB 3.26Å; T144-Y148 PolarHBondContact O-N 3.31Å
145	L	91.9	Very high	83.5	Confident	19 Å²	19	66.4 Å²	66.4	10%	0.099	32%	0.317	C	S	.	.	H	α-helix	trans	-65.5	-38.7	178.8	-172.7	66.5	0	0	0	112	W141 F142 R143 Y148 F149 M197 F198	W141-L145 WeakPolarHBondContact O-CB 3.47Å; W141-L145 PolarHBondContact O-N 3.09Å; F142-L145 PolarHBondContact O-N 3.02Å; R143-L145 VanDerWaalsContact C-N 3.31Å; R143-L145 PolarHBondContact O-N 3.29Å; L145-Y148 WeakPolarHBondContact O-CB 3.32Å; L145-Y148 PolarHBondContact O-N 3.05Å; L145-F149 HydrophobicContact CD1-CD2 4.25Å; L145-F149 HydrophobicContact CD1-CE2 3.74Å; L145-F149 HydrophobicContact CD1-CZ 4.43Å; L145-F149 HydrophobicContact CD2-CE2 4.14Å; L145-F149 HydrophobicContact CG-CD2 3.98Å; L145-F149 HydrophobicContact CG-CE2 3.66Å; L145-F149 WeakPolarHBondContact O-CD2 3.35Å; L145-F149 PolarHBondContact O-N 2.76Å; L145-M197 HydrophobicContact CD1-CB 4.12Å; L145-F198 HydrophobicContact CD2-CB 3.81Å; L145-F198 HydrophobicContact CD2-CD2 3.77Å; L145-F198 HydrophobicContact CD2-CG 4.26Å
146	S	93.4	Very high	84.9	Confident	2 Å²	2	65 Å²	65	1%	0.014	31%	0.31	C	S	.	.	H	α-helix	trans	-65	-41.3	175.9	-61.1	0	0	0	0	112.4	F123 F142 R143 T144 F149 L150 T217	F123-S146 WeakPolarHBondContact CZ-O 3.36Å; F142-S146 VanDerWaalsContact CE2-OG 3.29Å; F142-S146 WeakPolarHBondContact CE2-OG 3.24Å; F142-S146 WeakPolarHBondContact O-CB 3.46Å; F142-S146 PolarHBondContact O-N 3.32Å; F142-S146 PolarHBondContact O-OG 2.9Å; R143-S146 PolarHBondContact O-N 2.86Å; T144-S146 PolarHBondContact O-N 3.13Å; S146-F149 PolarHBondContact O-N 3.42Å; S146-L150 PolarHBondContact O-N 3.14Å; S146-T217 PolarHBondContact OG-OG1 3.43Å
147	W	95.1	Very high	86.5	Confident	95 Å²	95	62.9 Å²	62.9	36%	0.36	29%	0.29	S	S	.	.	H	α-helix	trans	-67.3	-35	173.1	-76.6	109.3	0	0	0	112.8	V120 H124 R143 T144 L150 L151	V120-W147 HydrophobicContact CG1-CH2 4Å; V120-W147 HydrophobicContact CG1-CZ3 3.9Å; H124-W147 HydrophobicContact CB-CH2 4.18Å; H124-W147 HydrophobicContact CB-CZ2 4.2Å; H124-W147 AromaticContact CD2-CZ2 3.78Å; R143-W147 PolarHBondContact O-N 2.81Å; T144-W147 PolarHBondContact O-N 2.96Å; W147-L150 HydrophobicContact CE3-CD2 3.53Å; W147-L150 HydrophobicContact CZ3-CD2 3.46Å; W147-L150 VanDerWaalsContact CZ3-CD2 3.46Å; W147-L150 WeakPolarHBondContact O-CB 3.06Å; W147-L150 PolarHBondContact O-N 3.48Å; W147-L151 PolarHBondContact O-N 3.34Å
148	Y	96.6	Very high	87.9	Confident	58 Å²	58	59.8 Å²	59.8	23%	0.227	28%	0.278	C	S	.	.	H	α-helix	trans	-60.6	-49.3	173.3	177.7	-91.7	0	0	0	111.3	T144 L145 L150 L151 C152 L190 M197	T144-Y148 WeakPolarHBondContact O-CB 3.26Å; T144-Y148 PolarHBondContact O-N 3.31Å; L145-Y148 WeakPolarHBondContact O-CB 3.32Å; L145-Y148 PolarHBondContact O-N 3.05Å; Y148-L150 VanDerWaalsContact C-N 3.31Å; Y148-L150 PolarHBondContact O-N 3.46Å; Y148-L151 PolarHBondContact O-N 3.12Å; Y148-L151 VanDerWaalsContact O-N 3.16Å; Y148-C152 WeakPolarHBondContact CE1-SG 3.18Å; Y148-C152 VanDerWaalsContact CZ-SG 3.53Å; Y148-C152 PolarHBondContact O-N 3Å; Y148-C152 PolarHBondContact O-SG 3.39Å; Y148-L190 WeakPolarHBondContact CE1-O 3.48Å; Y148-L190 PolarHBondContact OH-O 2.93Å; Y148-M197 HydrophobicContact CD1-CE 3.79Å; Y148-M197 HydrophobicContact CD2-CE 3.93Å; Y148-M197 HydrophobicContact CE1-CE 3.59Å; Y148-M197 HydrophobicContact CE2-CE 3.73Å; Y148-M197 HydrophobicContact CG-CE 3.95Å
149	F	97.4	Very high	89.1	Confident	2 Å²	2	54 Å²	54	1%	0.009	25%	0.251	C	S	.	.	H	α-helix	trans	-63.7	-35.5	176.6	-77	-64.1	0	0	0	112.5	L145 S146 L151 C152 V153 Y191 G194 F214 T217 L221	L145-F149 HydrophobicContact CD1-CD2 4.25Å; L145-F149 HydrophobicContact CD1-CE2 3.74Å; L145-F149 HydrophobicContact CD1-CZ 4.43Å; L145-F149 HydrophobicContact CD2-CE2 4.14Å; L145-F149 HydrophobicContact CG-CD2 3.98Å; L145-F149 HydrophobicContact CG-CE2 3.66Å; L145-F149 WeakPolarHBondContact O-CD2 3.35Å; L145-F149 PolarHBondContact O-N 2.76Å; S146-F149 PolarHBondContact O-N 3.42Å; F149-L151 PolarHBondContact O-N 3.02Å; F149-C152 PolarHBondContact O-N 3.41Å; F149-V153 WeakPolarHBondContact O-CB 3.44Å; F149-V153 WeakPolarHBondContact O-CG2 3.44Å; F149-V153 PolarHBondContact O-N 3.12Å; F149-Y191 HydrophobicContact CD1-CD2 4.16Å; F149-Y191 HydrophobicContact CD1-CE2 4.22Å; F149-Y191 AromaticContact CE1-CD2 3.98Å; F149-Y191 HydrophobicContact CE1-CD2 3.98Å; F149-Y191 AromaticContact CE1-CE2 3.92Å; F149-Y191 HydrophobicContact CE1-CE2 3.92Å; F149-G194 VanDerWaalsContact CZ-C 3.48Å; F149-F214 HydrophobicContact CE2-CD2 4.29Å; F149-F214 AromaticContact CE2-CE2 3.77Å; F149-F214 HydrophobicContact CE2-CE2 3.77Å; F149-F214 AromaticContact CZ-CE2 3.73Å; F149-F214 HydrophobicContact CZ-CE2 3.73Å; F149-F214 HydrophobicContact CZ-CZ 4.43Å; F149-T217 HydrophobicContact CB-CG2 4.3Å; F149-T217 HydrophobicContact CD2-CG2 4.49Å; F149-L221 HydrophobicContact CB-CD1 3.62Å
150	L	97	Very high	89.9	Confident	8 Å²	8	55.1 Å²	55.1	4%	0.042	26%	0.255	C	S	.	.	H	α-helix	trans	-56.5	-50.3	171.3	-176.5	71.6	0	0	0	111.1	V120 F123 S146 W147 Y148 C152 V153 N154 L221 V225	V120-L150 HydrophobicContact CG2-CD2 4.46Å; F123-L150 HydrophobicContact CB-CD1 4.24Å; F123-L150 HydrophobicContact CD1-CB 4.35Å; F123-L150 HydrophobicContact CD1-CD1 3.96Å; F123-L150 HydrophobicContact CD1-CD2 3.66Å; F123-L150 HydrophobicContact CD1-CG 4.2Å; F123-L150 HydrophobicContact CD2-CD1 3.9Å; F123-L150 HydrophobicContact CE1-CB 3.89Å; F123-L150 HydrophobicContact CE1-CD1 4.26Å; F123-L150 HydrophobicContact CE1-CD2 3.95Å; F123-L150 HydrophobicContact CE1-CG 4.25Å; F123-L150 HydrophobicContact CE2-CD1 4.25Å; F123-L150 HydrophobicContact CG-CD1 3.75Å; F123-L150 HydrophobicContact CG-CD2 4.24Å; F123-L150 HydrophobicContact CG-CG 4.49Å; F123-L150 HydrophobicContact CZ-CB 4.02Å; F123-L150 HydrophobicContact CZ-CD1 4.39Å; S146-L150 PolarHBondContact O-N 3.14Å; W147-L150 HydrophobicContact CE3-CD2 3.53Å; W147-L150 HydrophobicContact CZ3-CD2 3.46Å; W147-L150 VanDerWaalsContact CZ3-CD2 3.46Å; W147-L150 WeakPolarHBondContact O-CB 3.06Å; W147-L150 PolarHBondContact O-N 3.48Å; Y148-L150 VanDerWaalsContact C-N 3.31Å; Y148-L150 PolarHBondContact O-N 3.46Å; L150-C152 VanDerWaalsContact C-N 3.34Å; L150-C152 PolarHBondContact O-N 3.01Å; L150-V153 PolarHBondContact O-N 3.34Å; L150-N154 VanDerWaalsContact CD1-ND2 3.34Å; L150-N154 WeakPolarHBondContact CD1-ND2 3.32Å; L150-N154 WeakPolarHBondContact O-CB 3.31Å; L150-N154 PolarHBondContact O-N 2.89Å; L150-N154 PolarHBondContact O-ND2 2.94Å; L150-L221 HydrophobicContact CB-CD2 4.06Å; L150-L221 HydrophobicContact CD1-CD2 3.58Å; L150-L221 HydrophobicContact CG-CD2 4.44Å; L150-V225 HydrophobicContact CD1-CG2 3.8Å
151	L	96.5	Very high	90.9	Very high	113 Å²	113	51.6 Å²	51.6	59%	0.592	23%	0.232	S	C	*	.	H	α-helix	trans	-60.7	-43.6	178.6	-174.4	149.4	0	0	0	111.6	W147 Y148 F149 N154 Y155	W147-L151 PolarHBondContact O-N 3.34Å; Y148-L151 PolarHBondContact O-N 3.12Å; Y148-L151 VanDerWaalsContact O-N 3.16Å; F149-L151 PolarHBondContact O-N 3.02Å; L151-N154 PolarHBondContact O-N 2.98Å; L151-Y155 WeakPolarHBondContact O-CB 3.36Å; L151-Y155 PolarHBondContact O-N 3.45Å
152	C	96.6	Very high	91.3	Very high	5 Å²	5	45.8 Å²	45.8	3%	0.034	22%	0.216	C	C	.	.	H	α-helix	trans	-61.6	-47.4	179.4	-64.7	0	0	0	0	112.3	Y148 F149 L150 Y155 F156	Y148-C152 WeakPolarHBondContact CE1-SG 3.18Å; Y148-C152 VanDerWaalsContact CZ-SG 3.53Å; Y148-C152 PolarHBondContact O-N 3Å; Y148-C152 PolarHBondContact O-SG 3.39Å; F149-C152 PolarHBondContact O-N 3.41Å; L150-C152 VanDerWaalsContact C-N 3.34Å; L150-C152 PolarHBondContact O-N 3.01Å; C152-Y155 PolarHBondContact O-N 3.35Å; C152-F156 PolarHBondContact O-N 3.49Å
153	V	96.6	Very high	91.2	Very high	26 Å²	26	45.9 Å²	45.9	16%	0.158	22%	0.221	C	C	.	.	H	α-helix	trans	-70.8	-36.6	-178.8	178	0	0	0	0	111.2	F149 L150 F156 F157 L221 V225	F149-V153 WeakPolarHBondContact O-CB 3.44Å; F149-V153 WeakPolarHBondContact O-CG2 3.44Å; F149-V153 PolarHBondContact O-N 3.12Å; L150-V153 PolarHBondContact O-N 3.34Å; V153-F156 PolarHBondContact O-N 2.98Å; V153-F157 HydrophobicContact CG1-CD2 3.61Å; V153-F157 HydrophobicContact CG1-CE2 3.66Å; V153-F157 WeakPolarHBondContact O-CD2 3.31Å; V153-F157 PolarHBondContact O-N 2.9Å; V153-F157 VanDerWaalsContact O-N 3.09Å; V153-L221 HydrophobicContact CG2-CD1 4.03Å; V153-V225 HydrophobicContact CG1-CB 3.98Å; V153-V225 HydrophobicContact CG1-CG1 3.8Å; V153-V225 HydrophobicContact CG1-CG2 4.33Å
154	N	96.1	Very high	90.8	Very high	26 Å²	26	42.2 Å²	42.2	14%	0.139	22%	0.215	C	C	.	.	H	α-helix	trans	-63.6	-45.3	172.6	-83.3	-104.4	0	0	0	110.9	Q119 L150 L151 F156 Y158	Q119-N154 PolarHBondContact NE2-ND2 2.9Å; Q119-N154 PolarHBondContact NE2-OD1 3.27Å; Q119-N154 PolarHBondContact OE1-OD1 2.81Å; L150-N154 VanDerWaalsContact CD1-ND2 3.34Å; L150-N154 WeakPolarHBondContact CD1-ND2 3.32Å; L150-N154 WeakPolarHBondContact O-CB 3.31Å; L150-N154 PolarHBondContact O-N 2.89Å; L150-N154 PolarHBondContact O-ND2 2.94Å; L151-N154 PolarHBondContact O-N 2.98Å; N154-F156 VanDerWaalsContact C-N 3.33Å; N154-F156 PolarHBondContact O-N 3.09Å; N154-Y158 HydrophobicContact CB-CD2 3.95Å; N154-Y158 HydrophobicContact CB-CE2 4.36Å; N154-Y158 VanDerWaalsContact O-CB 3.26Å; N154-Y158 WeakPolarHBondContact O-CB 3.27Å; N154-Y158 VanDerWaalsContact O-CD2 3.26Å; N154-Y158 WeakPolarHBondContact O-CD2 3.36Å; N154-Y158 PolarHBondContact O-N 3.5Å; N154-Y158 WeakPolarHBondContact OD1-CE2 3.36Å
155	Y	94.7	Very high	90	Very high	58 Å²	58	41 Å²	41	23%	0.227	20%	0.202	C	C	.	.	H	α-helix	trans	-55.2	-51	175.1	177.4	-104.4	0	0	0	110.2	L151 C152 G159 L179 H183 I186 S187 L190	L151-Y155 WeakPolarHBondContact O-CB 3.36Å; L151-Y155 PolarHBondContact O-N 3.45Å; C152-Y155 PolarHBondContact O-N 3.35Å; Y155-G159 VanDerWaalsContact O-CA 3.26Å; Y155-G159 WeakPolarHBondContact O-CA 3.44Å; Y155-G159 PolarHBondContact O-N 3.32Å; Y155-L179 PolarHBondContact OH-O 2.86Å; Y155-H183 AromaticContact CD1-CE1 3.84Å; Y155-H183 AromaticContact CE1-CE1 3.66Å; Y155-H183 AromaticContact CE1-ND1 3.43Å; Y155-H183 WeakPolarHBondContact CE1-ND1 3.29Å; Y155-H183 AromaticContact CZ-CE1 3.95Å; Y155-H183 AromaticContact CZ-ND1 3.41Å; Y155-H183 PolarHBondContact O-CE1 2.98Å; Y155-I186 HydrophobicContact CE1-CB 4.11Å; Y155-I186 HydrophobicContact CE1-CG2 3.7Å; Y155-S187 VanDerWaalsContact CD1-OG 3.23Å; Y155-S187 WeakPolarHBondContact CD1-OG 3.33Å; Y155-S187 VanDerWaalsContact CE1-OG 3.28Å; Y155-S187 WeakPolarHBondContact CE1-OG 3.27Å; Y155-L190 HydrophobicContact CD1-CD1 3.99Å; Y155-L190 HydrophobicContact CE1-CD1 4.3Å
156	F	95	Very high	89.1	Confident	73 Å²	73	41 Å²	41	32%	0.32	20%	0.201	S	C	.	.	H	α-helix	trans	-54.5	-58.8	179.1	179.2	-105.6	0	0	0	113.3	C152 V153 N154 E160 H183	C152-F156 PolarHBondContact O-N 3.49Å; V153-F156 PolarHBondContact O-N 2.98Å; N154-F156 VanDerWaalsContact C-N 3.33Å; N154-F156 PolarHBondContact O-N 3.09Å; F156-E160 PolarHBondContact O-N 3.36Å; F156-H183 PolarHBondContact O-NE2 3.42Å
157	F	93.4	Very high	88	Confident	42 Å²	42	42.5 Å²	42.5	18%	0.184	21%	0.214	C	C	.	.	H	α-helix	trans	-71.5	-44.1	-174.8	-79.1	-68.1	0	0	0	113.5	V153 T161 V225 H229	V153-F157 HydrophobicContact CG1-CD2 3.61Å; V153-F157 HydrophobicContact CG1-CE2 3.66Å; V153-F157 WeakPolarHBondContact O-CD2 3.31Å; V153-F157 PolarHBondContact O-N 2.9Å; V153-F157 VanDerWaalsContact O-N 3.09Å; F157-T161 PolarHBondContact O-N 3.45Å; F157-T161 PolarHBondContact O-OG1 3.36Å; F157-V225 HydrophobicContact CD2-CG1 4.05Å; F157-H229 HydrophobicContact CB-CB 4.14Å; F157-H229 HydrophobicContact CD1-CB 4.34Å; F157-H229 AromaticContact CD1-CD2 3.5Å; F157-H229 VanDerWaalsContact CD1-CD2 3.5Å; F157-H229 WeakPolarHBondContact CD1-CD2 3.39Å; F157-H229 AromaticContact CD1-CG 3.79Å; F157-H229 AromaticContact CD1-NE2 3.72Å; F157-H229 HydrophobicContact CG-CB 4.31Å; F157-H229 PolarHBondContact O-CE1 3.16Å; F157-H229 VanDerWaalsContact O-CE1 3.3Å; F157-H229 PolarHBondContact O-ND1 3.46Å
158	Y	90	Very high	86.7	Confident	26 Å²	26	41.4 Å²	41.4	10%	0.102	22%	0.217	C	C	.	.	H	α-helix	trans	-78.8	-28.9	-178.1	-65.5	-65.1	0	0	0	112.3	L116 Q119 N154 E160 T161 V162 V225 S228 H229 I232	L116-Y158 HydrophobicContact CD2-CD1 4.2Å; L116-Y158 HydrophobicContact CD2-CD2 3.85Å; L116-Y158 HydrophobicContact CD2-CE1 3.73Å; L116-Y158 HydrophobicContact CD2-CE2 3.3Å; L116-Y158 HydrophobicContact CD2-CG 4.27Å; L116-Y158 WeakPolarHBondContact CD2-OH 3.43Å; Q119-Y158 PolarHBondContact OE1-OH 2.9Å; Q119-Y158 VanDerWaalsContact OE1-OH 3.04Å; N154-Y158 HydrophobicContact CB-CD2 3.95Å; N154-Y158 HydrophobicContact CB-CE2 4.36Å; N154-Y158 VanDerWaalsContact O-CB 3.26Å; N154-Y158 WeakPolarHBondContact O-CB 3.27Å; N154-Y158 VanDerWaalsContact O-CD2 3.26Å; N154-Y158 WeakPolarHBondContact O-CD2 3.36Å; N154-Y158 PolarHBondContact O-N 3.5Å; N154-Y158 WeakPolarHBondContact OD1-CE2 3.36Å; Y158-E160 VanDerWaalsContact C-N 3.35Å; Y158-T161 PolarHBondContact O-N 3.4Å; Y158-V162 WeakPolarHBondContact O-CB 3.48Å; Y158-V162 VanDerWaalsContact O-CG2 3.25Å; Y158-V162 WeakPolarHBondContact O-CG2 3.36Å; Y158-V162 PolarHBondContact O-N 2.8Å; Y158-V225 HydrophobicContact CE2-CG1 4.31Å; Y158-S228 VanDerWaalsContact OH-CB 3.3Å; Y158-S228 WeakPolarHBondContact OH-CB 3.31Å; Y158-S228 PolarHBondContact OH-OG 3.44Å; Y158-H229 PolarHBondContact OH-N 3.28Å; Y158-I232 HydrophobicContact CD1-CD1 4.36Å; Y158-I232 HydrophobicContact CE1-CD1 3.37Å; Y158-I232 HydrophobicContact CE1-CG1 4.5Å
159	G	86.5	Confident	85.4	Confident	16 Å²	16	42.8 Å²	42.8	17%	0.165	23%	0.225	C	C	.	.	H	α-helix	trans	-62.5	-40.1	170.9	0	0	0	0	0	112.3	Y155 V162 A163	Y155-G159 VanDerWaalsContact O-CA 3.26Å; Y155-G159 WeakPolarHBondContact O-CA 3.44Å; Y155-G159 PolarHBondContact O-N 3.32Å; G159-V162 PolarHBondContact O-N 2.98Å; G159-A163 WeakPolarHBondContact O-CB 3.29Å; G159-A163 PolarHBondContact O-N 3.34Å
160	E	83.8	Confident	84	Confident	50 Å²	50	43.1 Å²	43.1	23%	0.234	23%	0.227	C	C	.	.	H	α-helix	trans	-65.1	-41.1	172.2	-73.4	-162.1	145	0	0	111.7	F156 Y158 V162 A163 D164 H183 R184	F156-E160 PolarHBondContact O-N 3.36Å; Y158-E160 VanDerWaalsContact C-N 3.35Å; E160-V162 PolarHBondContact O-N 3.07Å; E160-A163 PolarHBondContact O-N 2.68Å; E160-D164 WeakPolarHBondContact O-CB 3.45Å; E160-D164 PolarHBondContact O-N 2.88Å; E160-H183 PolarHBondContact N-NE2 3.28Å; E160-R184 IonicContact OE1-CZ 3.59Å; E160-R184 IonicContact OE1-NE 3.06Å; E160-R184 PolarHBondContact OE1-NE 3.34Å; E160-R184 IonicContact OE1-NH2 3.19Å; E160-R184 PolarHBondContact OE1-NH2 3.04Å
161	T	83.4	Confident	82.7	Confident	5 Å²	5	48.8 Å²	48.8	3%	0.031	25%	0.253	C	S	.	.	H	α-helix	trans	-63.4	-43.3	176.8	-49.3	0	0	0	0	111.7	F157 Y158 A163 D164 Y165 H229 I232 F236	F157-T161 PolarHBondContact O-N 3.45Å; F157-T161 PolarHBondContact O-OG1 3.36Å; Y158-T161 PolarHBondContact O-N 3.4Å; T161-A163 VanDerWaalsContact C-N 3.34Å; T161-D164 PolarHBondContact O-N 3.32Å; T161-Y165 HydrophobicContact CG2-CD2 3.9Å; T161-Y165 HydrophobicContact CG2-CE2 4.28Å; T161-Y165 WeakPolarHBondContact O-CD2 3.44Å; T161-Y165 PolarHBondContact O-N 2.96Å; T161-H229 PolarHBondContact OG1-CE1 3.4Å; T161-H229 PolarHBondContact OG1-ND1 3.44Å; T161-I232 HydrophobicContact CG2-CG2 4.34Å; T161-F236 HydrophobicContact CG2-CD2 3.92Å; T161-F236 HydrophobicContact CG2-CE2 3.62Å
162	V	80.3	Confident	81.5	Confident	58 Å²	58	50.3 Å²	50.3	35%	0.352	25%	0.251	S	S	.	.	H	α-helix	trans	-63.6	-42.8	176.3	169.7	0	0	0	0	110.2	Y158 G159 E160 D164 F166 V170	Y158-V162 WeakPolarHBondContact O-CB 3.48Å; Y158-V162 VanDerWaalsContact O-CG2 3.25Å; Y158-V162 WeakPolarHBondContact O-CG2 3.36Å; Y158-V162 PolarHBondContact O-N 2.8Å; G159-V162 PolarHBondContact O-N 2.98Å; E160-V162 PolarHBondContact O-N 3.07Å; V162-D164 VanDerWaalsContact C-N 3.34Å; V162-D164 PolarHBondContact O-N 2.86Å; V162-F166 HydrophobicContact CB-CD2 4.45Å; V162-F166 HydrophobicContact CG1-CB 4.24Å; V162-F166 CarbonylContact O-C 3.26Å; V162-F166 VanDerWaalsContact O-CA 3.26Å; V162-F166 WeakPolarHBondContact O-CA 3.27Å; V162-F166 WeakPolarHBondContact O-CB 3.37Å; V162-F166 PolarHBondContact O-N 2.89Å; V162-V170 HydrophobicContact CG1-CG2 3.98Å
163	A	77.6	Confident	80.6	Confident	24 Å²	24	55.2 Å²	55.2	20%	0.198	27%	0.274	C	S	.	.	H	α-helix	trans	-61.9	-41.2	176.2	0	0	0	0	0	112.2	G159 E160 T161 A167 I180	G159-A163 WeakPolarHBondContact O-CB 3.29Å; G159-A163 PolarHBondContact O-N 3.34Å; E160-A163 PolarHBondContact O-N 2.68Å; T161-A163 VanDerWaalsContact C-N 3.34Å; A163-A167 VanDerWaalsContact O-CB 3.31Å; A163-A167 WeakPolarHBondContact O-CB 3.48Å; A163-A167 PolarHBondContact O-N 3.47Å; A163-I180 HydrophobicContact CB-CD1 4.36Å; A163-I180 HydrophobicContact CB-CG2 3.9Å
164	D	74.8	Confident	79.6	Confident	101 Å²	101	61.9 Å²	61.9	54%	0.54	30%	0.303	S	S	.	.	H	α-helix	trans	-73.2	-44.5	-177.6	-82.2	-10.2	0	0	0	113.3	E160 T161 V162	E160-D164 WeakPolarHBondContact O-CB 3.45Å; E160-D164 PolarHBondContact O-N 2.88Å; T161-D164 PolarHBondContact O-N 3.32Å; V162-D164 VanDerWaalsContact C-N 3.34Å; V162-D164 PolarHBondContact O-N 2.86Å
165	Y	74.2	Confident	78.7	Confident	54 Å²	54	68.5 Å²	68.5	21%	0.212	33%	0.333	C	S	.	.	H	α-helix	trans	-96.9	-19.3	-172.9	-70.8	-90.4	0	0	0	113.7	T161 F236 E237 R419	T161-Y165 HydrophobicContact CG2-CD2 3.9Å; T161-Y165 HydrophobicContact CG2-CE2 4.28Å; T161-Y165 WeakPolarHBondContact O-CD2 3.44Å; T161-Y165 PolarHBondContact O-N 2.96Å; Y165-F236 HydrophobicContact CD1-CB 4.11Å; Y165-F236 HydrophobicContact CD1-CD2 4.12Å; Y165-F236 HydrophobicContact CD1-CG 4.44Å; Y165-F236 AromaticContact CD2-CD2 3.78Å; Y165-F236 HydrophobicContact CD2-CD2 3.78Å; Y165-F236 HydrophobicContact CD2-CE2 4.4Å; Y165-F236 HydrophobicContact CE1-CB 3.62Å; Y165-F236 HydrophobicContact CE1-CD2 4.27Å; Y165-F236 HydrophobicContact CE1-CG 4.38Å; Y165-F236 HydrophobicContact CE2-CB 4.35Å; Y165-F236 AromaticContact CE2-CD2 3.93Å; Y165-F236 HydrophobicContact CE2-CD2 3.93Å; Y165-F236 AromaticContact CG-CD2 3.88Å; Y165-F236 HydrophobicContact CG-CD2 3.88Å; Y165-F236 HydrophobicContact CG-CE2 4.46Å; Y165-E237 PolarHBondContact OH-OE1 3.01Å; Y165-R419 PolarHBondContact OH-NH2 3.4Å
166	F	72.8	Confident	78	Confident	20 Å²	20	68.9 Å²	68.9	9%	0.088	34%	0.339	C	S	.	.	H	α-helix	trans	-124.1	15.8	-172.3	-49.7	-116	0	0	0	112.3	V162 T168 F169 V170 F236 F317	V162-F166 HydrophobicContact CB-CD2 4.45Å; V162-F166 HydrophobicContact CG1-CB 4.24Å; V162-F166 CarbonylContact O-C 3.26Å; V162-F166 VanDerWaalsContact O-CA 3.26Å; V162-F166 WeakPolarHBondContact O-CA 3.27Å; V162-F166 WeakPolarHBondContact O-CB 3.37Å; V162-F166 PolarHBondContact O-N 2.89Å; F166-T168 PolarHBondContact O-N 3.4Å; F166-T168 VanDerWaalsContact O-N 3.14Å; F166-F169 HydrophobicContact CB-CB 4.47Å; F166-F169 PolarHBondContact O-N 3.13Å; F166-F169 VanDerWaalsContact O-N 3.08Å; F166-V170 HydrophobicContact CB-CG2 4.23Å; F166-V170 WeakPolarHBondContact O-CG2 3.33Å; F166-V170 PolarHBondContact O-N 3.47Å; F166-F236 HydrophobicContact CE2-CE2 4.01Å; F166-F236 HydrophobicContact CE2-CZ 4.26Å; F166-F236 HydrophobicContact CZ-CE2 4.36Å; F166-F236 HydrophobicContact CZ-CZ 4.15Å; F166-F317 AromaticContact CD1-CE1 3.56Å; F166-F317 HydrophobicContact CD1-CE1 3.56Å; F166-F317 AromaticContact CD1-CZ 3.67Å; F166-F317 HydrophobicContact CD1-CZ 3.67Å; F166-F317 HydrophobicContact CE1-CD1 4.27Å; F166-F317 AromaticContact CE1-CE1 3.1Å; F166-F317 HydrophobicContact CE1-CE1 3.1Å; F166-F317 HydrophobicContact CE1-CE2 4.39Å; F166-F317 AromaticContact CE1-CZ 3.2Å; F166-F317 HydrophobicContact CE1-CZ 3.2Å; F166-F317 AromaticContact CZ-CE1 3.93Å; F166-F317 HydrophobicContact CZ-CE1 3.93Å; F166-F317 HydrophobicContact CZ-CZ 4.29Å
167	A	69.6	Low	77.3	Confident	33 Å²	33	69.7 Å²	69.7	27%	0.273	34%	0.343	S	S	.	.	H	α-helix	trans	-47.2	-45.6	179.3	0	0	0	0	0	113	A163 V170 Q171	A163-A167 VanDerWaalsContact O-CB 3.31Å; A163-A167 WeakPolarHBondContact O-CB 3.48Å; A163-A167 PolarHBondContact O-N 3.47Å; A167-V170 PolarHBondContact O-N 3.15Å; A167-Q171 VanDerWaalsContact O-CB 3.25Å; A167-Q171 WeakPolarHBondContact O-CB 3.35Å; A167-Q171 WeakPolarHBondContact O-CG 3.19Å; A167-Q171 PolarHBondContact O-N 2.92Å
168	T	67.5	Low	76.9	Confident	71 Å²	71	73.3 Å²	73.3	44%	0.436	36%	0.359	S	S	.	.	H	α-helix	trans	-66.5	-38.8	-177.7	48.6	0	0	0	0	113.1	F166	F166-T168 PolarHBondContact O-N 3.4Å; F166-T168 VanDerWaalsContact O-N 3.14Å
169	F	68.8	Low	76.7	Confident	87 Å²	87	75.5 Å²	75.5	38%	0.382	37%	0.372	S	S	.	.	H	α-helix	trans	-66.3	-49.2	174.7	175.6	-109.4	0	0	0	110.5	F166 Q171 R172 Y310	F166-F169 HydrophobicContact CB-CB 4.47Å; F166-F169 PolarHBondContact O-N 3.13Å; F166-F169 VanDerWaalsContact O-N 3.08Å; F169-Q171 PolarHBondContact O-N 3Å; F169-R172 PolarHBondContact O-N 3.49Å; F169-Y310 HydrophobicContact CB-CD1 3.86Å; F169-Y310 HydrophobicContact CB-CE1 3.69Å; F169-Y310 HydrophobicContact CB-CE2 4.44Å; F169-Y310 HydrophobicContact CB-CG 4.32Å; F169-Y310 AromaticContact CD2-CE1 3.94Å; F169-Y310 HydrophobicContact CD2-CE1 3.94Å; F169-Y310 HydrophobicContact CD2-CE2 4.05Å; F169-Y310 AromaticContact CD2-CZ 3.48Å; F169-Y310 VanDerWaalsContact CD2-CZ 3.48Å; F169-Y310 VanDerWaalsContact CD2-OH 3.26Å; F169-Y310 WeakPolarHBondContact CD2-OH 3.48Å; F169-Y310 HydrophobicContact CG-CE1 4.25Å; F169-Y310 HydrophobicContact CG-CE2 4.42Å
170	V	69.4	Low	76.5	Confident	9 Å²	9	77.4 Å²	77.4	6%	0.055	38%	0.378	C	S	.	.	H	α-helix	trans	-75	-27.5	-171.6	-173.6	0	0	0	0	112.4	V162 F166 A167 R172 E173 L176 I180	V162-V170 HydrophobicContact CG1-CG2 3.98Å; F166-V170 HydrophobicContact CB-CG2 4.23Å; F166-V170 WeakPolarHBondContact O-CG2 3.33Å; F166-V170 PolarHBondContact O-N 3.47Å; A167-V170 PolarHBondContact O-N 3.15Å; V170-R172 PolarHBondContact O-N 3.45Å; V170-E173 PolarHBondContact O-N 3.4Å; V170-L176 HydrophobicContact CG1-CB 3.26Å; V170-L176 HydrophobicContact CG1-CD1 4Å; V170-L176 HydrophobicContact CG1-CG 4.25Å; V170-I180 HydrophobicContact CB-CD1 3.45Å; V170-I180 VanDerWaalsContact CB-CD1 3.45Å; V170-I180 HydrophobicContact CG1-CD1 3.2Å; V170-I180 HydrophobicContact CG1-CG1 3.92Å; V170-I180 HydrophobicContact CG2-CD1 3.96Å
171	Q	69.3	Low	76.6	Confident	127 Å²	127	84.3 Å²	84.3	59%	0.593	40%	0.402	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.8	-13.9	173	-79.3	175.7	5.6	0	0	114	A167 F169 E173 Q177	A167-Q171 VanDerWaalsContact O-CB 3.25Å; A167-Q171 WeakPolarHBondContact O-CB 3.35Å; A167-Q171 WeakPolarHBondContact O-CG 3.19Å; A167-Q171 PolarHBondContact O-N 2.92Å; F169-Q171 PolarHBondContact O-N 3Å; Q171-E173 VanDerWaalsContact C-N 3.35Å; Q171-Q177 PolarHBondContact O-NE2 2.81Å
172	R	71.1	Confident	76.8	Confident	145 Å²	145	88.6 Å²	88.6	55%	0.547	42%	0.418	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.5	-25	173.9	-74	-178.4	167.2	165.5	-3.1	113.1	F169 V170 S312 N315	F169-R172 PolarHBondContact O-N 3.49Å; V170-R172 PolarHBondContact O-N 3.45Å; R172-S312 PolarHBondContact NH1-O 2.82Å; R172-S312 PolarHBondContact NH2-O 3Å; R172-N315 PolarHBondContact NH1-OD1 3.09Å
173	E	77.1	Confident	77.3	Confident	109 Å²	109	86.3 Å²	86.3	51%	0.509	40%	0.404	S	S	.	.			trans	-105	110.2	-174.2	-70	-66.1	164.6	0	0	110.8	V170 Q171 Q175 L176 Q177	V170-E173 PolarHBondContact O-N 3.4Å; Q171-E173 VanDerWaalsContact C-N 3.35Å; E173-Q175 PolarHBondContact O-N 3.05Å; E173-L176 HydrophobicContact CB-CB 4.17Å; E173-L176 HydrophobicContact CB-CD1 3.85Å; E173-L176 HydrophobicContact CB-CG 3.98Å; E173-L176 HydrophobicContact CG-CD1 4.23Å; E173-L176 PolarHBondContact O-N 3.43Å; E173-Q177 PolarHBondContact O-N 3.42Å; E173-Q177 VanDerWaalsContact O-N 3.12Å
174	E	77.4	Confident	78	Confident	165 Å²	165	93.7 Å²	93.7	77%	0.771	43%	0.427	S	S	*	.	H	α-helix	trans	-56.4	-37.3	-174.6	-167.7	177.8	-176.9	0	0	112.8	L176 Q177	E174-L176 VanDerWaalsContact C-N 3.34Å; E174-L176 PolarHBondContact O-N 2.96Å; E174-Q177 PolarHBondContact O-N 3.1Å
175	Q	77.2	Confident	79	Confident	166 Å²	166	95.8 Å²	95.8	78%	0.776	43%	0.431	S	S	*	.	H	α-helix	trans	-65.5	-36.2	178	-65	-175.3	-14.4	0	0	112.8	E173	E173-Q175 PolarHBondContact O-N 3.05Å
176	L	79	Confident	80	Confident	66 Å²	66	94.9 Å²	94.9	35%	0.346	43%	0.43	S	S	.	.	H	α-helix	trans	-82.4	-24.3	-178.2	-59.6	177.8	0	0	0	112.2	V170 E173 E174 F178 L179 I180	V170-L176 HydrophobicContact CG1-CB 3.26Å; V170-L176 HydrophobicContact CG1-CD1 4Å; V170-L176 HydrophobicContact CG1-CG 4.25Å; E173-L176 HydrophobicContact CB-CB 4.17Å; E173-L176 HydrophobicContact CB-CD1 3.85Å; E173-L176 HydrophobicContact CB-CG 3.98Å; E173-L176 HydrophobicContact CG-CD1 4.23Å; E173-L176 PolarHBondContact O-N 3.43Å; E174-L176 VanDerWaalsContact C-N 3.34Å; E174-L176 PolarHBondContact O-N 2.96Å; L176-F178 VanDerWaalsContact C-N 3.3Å; L176-F178 PolarHBondContact O-N 3.39Å; L176-L179 HydrophobicContact CD2-CD1 4.18Å; L176-L179 PolarHBondContact O-N 2.69Å; L176-I180 PolarHBondContact O-N 2.87Å; L176-I180 VanDerWaalsContact O-N 3.08Å
177	Q	79.4	Confident	81.1	Confident	89 Å²	89	94.3 Å²	94.3	42%	0.416	43%	0.428	S	S	.	.	H	α-helix	trans	-58.1	-42	173.7	-70.5	-175.7	6.7	0	0	112.2	Q171 E173 E174 L179 I180 R181	Q171-Q177 PolarHBondContact O-NE2 2.81Å; E173-Q177 PolarHBondContact O-N 3.42Å; E173-Q177 VanDerWaalsContact O-N 3.12Å; E174-Q177 PolarHBondContact O-N 3.1Å; Q177-L179 VanDerWaalsContact C-N 3.34Å; Q177-L179 PolarHBondContact O-N 3.33Å; Q177-I180 PolarHBondContact O-N 2.87Å; Q177-R181 VanDerWaalsContact O-CB 3.26Å; Q177-R181 WeakPolarHBondContact O-CB 3.29Å; Q177-R181 PolarHBondContact O-N 3.48Å
178	F	85.5	Confident	82.4	Confident	119 Å²	119	98.9 Å²	98.9	52%	0.522	44%	0.442	S	S	.	.	H	α-helix	trans	-59.4	-46.2	176.6	174.5	-96.5	0	0	0	111.4	L176 I180 R181 Y182 I186	L176-F178 VanDerWaalsContact C-N 3.3Å; L176-F178 PolarHBondContact O-N 3.39Å; F178-I180 PolarHBondContact O-N 3.33Å; F178-R181 PolarHBondContact O-N 2.95Å; F178-Y182 AromaticContact CD2-CD2 3.45Å; F178-Y182 HydrophobicContact CD2-CD2 3.45Å; F178-Y182 VanDerWaalsContact CD2-CD2 3.45Å; F178-Y182 AromaticContact CD2-CE2 3.66Å; F178-Y182 HydrophobicContact CD2-CE2 3.66Å; F178-Y182 AromaticContact CE2-CD2 3.37Å; F178-Y182 HydrophobicContact CE2-CD2 3.37Å; F178-Y182 AromaticContact CE2-CE2 3.64Å; F178-Y182 HydrophobicContact CE2-CE2 3.64Å; F178-Y182 HydrophobicContact CE2-CG 4.26Å; F178-Y182 HydrophobicContact CG-CD2 4.2Å; F178-Y182 HydrophobicContact CZ-CD2 4.07Å; F178-Y182 WeakPolarHBondContact O-CD2 3.35Å; F178-Y182 PolarHBondContact O-N 3.06Å; F178-I186 HydrophobicContact CD1-CD1 4.49Å; F178-I186 HydrophobicContact CE1-CD1 3.96Å
179	L	85.8	Confident	83.8	Confident	72 Å²	72	97.6 Å²	97.6	38%	0.377	44%	0.439	S	S	.	.	H	α-helix	trans	-63	-40.9	-179.3	-68.3	175.4	0	0	0	112.2	Y155 L176 Q177 H183 I186	Y155-L179 PolarHBondContact OH-O 2.86Å; L176-L179 HydrophobicContact CD2-CD1 4.18Å; L176-L179 PolarHBondContact O-N 2.69Å; Q177-L179 VanDerWaalsContact C-N 3.34Å; Q177-L179 PolarHBondContact O-N 3.33Å; L179-H183 WeakPolarHBondContact O-CA 3.37Å; L179-H183 VanDerWaalsContact O-CB 3.31Å; L179-H183 WeakPolarHBondContact O-CB 3.43Å; L179-H183 PolarHBondContact O-N 3.02Å; L179-I186 HydrophobicContact CD2-CD1 4.06Å
180	I	83.6	Confident	85.2	Confident	56 Å²	56	95.9 Å²	95.9	29%	0.287	43%	0.433	S	S	.	.	H	α-helix	trans	-69.9	-47	176.5	-70.2	-171.9	0	0	0	111.3	A163 V170 L176 Q177 F178 Y182 H183	A163-I180 HydrophobicContact CB-CD1 4.36Å; A163-I180 HydrophobicContact CB-CG2 3.9Å; V170-I180 HydrophobicContact CB-CD1 3.45Å; V170-I180 VanDerWaalsContact CB-CD1 3.45Å; V170-I180 HydrophobicContact CG1-CD1 3.2Å; V170-I180 HydrophobicContact CG1-CG1 3.92Å; V170-I180 HydrophobicContact CG2-CD1 3.96Å; L176-I180 PolarHBondContact O-N 2.87Å; L176-I180 VanDerWaalsContact O-N 3.08Å; Q177-I180 PolarHBondContact O-N 2.87Å; F178-I180 PolarHBondContact O-N 3.33Å; I180-Y182 VanDerWaalsContact C-N 3.3Å; I180-Y182 PolarHBondContact O-N 3.31Å; I180-H183 WeakPolarHBondContact O-CB 3.21Å; I180-H183 PolarHBondContact O-N 2.92Å
181	R	84.1	Confident	86.5	Confident	195 Å²	195	99.8 Å²	99.8	74%	0.736	45%	0.448	S	S	*	.	H	α-helix	trans	-60.1	-41.1	-176	178.1	174.8	172.3	174.5	-2.2	112.2	Q177 F178	Q177-R181 VanDerWaalsContact O-CB 3.26Å; Q177-R181 WeakPolarHBondContact O-CB 3.29Å; Q177-R181 PolarHBondContact O-N 3.48Å; F178-R181 PolarHBondContact O-N 2.95Å
182	Y	89.5	Confident	87.8	Confident	94 Å²	94	97.7 Å²	97.7	37%	0.369	44%	0.44	S	S	.	.	T	Hydrogen-bonded Turn	trans	-102.5	13.6	-179.6	-61.7	-75.8	0	0	0	113.1	F178 I180 R184 F185 I186	F178-Y182 AromaticContact CD2-CD2 3.45Å; F178-Y182 HydrophobicContact CD2-CD2 3.45Å; F178-Y182 VanDerWaalsContact CD2-CD2 3.45Å; F178-Y182 AromaticContact CD2-CE2 3.66Å; F178-Y182 HydrophobicContact CD2-CE2 3.66Å; F178-Y182 AromaticContact CE2-CD2 3.37Å; F178-Y182 HydrophobicContact CE2-CD2 3.37Å; F178-Y182 AromaticContact CE2-CE2 3.64Å; F178-Y182 HydrophobicContact CE2-CE2 3.64Å; F178-Y182 HydrophobicContact CE2-CG 4.26Å; F178-Y182 HydrophobicContact CG-CD2 4.2Å; F178-Y182 HydrophobicContact CZ-CD2 4.07Å; F178-Y182 WeakPolarHBondContact O-CD2 3.35Å; F178-Y182 PolarHBondContact O-N 3.06Å; I180-Y182 VanDerWaalsContact C-N 3.3Å; I180-Y182 PolarHBondContact O-N 3.31Å; Y182-R184 PolarHBondContact O-N 3.11Å; Y182-F185 PolarHBondContact O-N 3.36Å; Y182-I186 WeakPolarHBondContact O-CG1 3.23Å; Y182-I186 PolarHBondContact O-N 3.04Å
183	H	90.6	Very high	89.1	Confident	11 Å²	11	92.8 Å²	92.8	5%	0.051	43%	0.431	C	S	.	.	H	α-helix	trans	-46.8	-52.2	-173.6	177.2	54	0	0	0	113.9	Y155 F156 E160 L179 I180 F185 I186 S187	Y155-H183 AromaticContact CD1-CE1 3.84Å; Y155-H183 AromaticContact CE1-CE1 3.66Å; Y155-H183 AromaticContact CE1-ND1 3.43Å; Y155-H183 WeakPolarHBondContact CE1-ND1 3.29Å; Y155-H183 AromaticContact CZ-CE1 3.95Å; Y155-H183 AromaticContact CZ-ND1 3.41Å; Y155-H183 PolarHBondContact O-CE1 2.98Å; F156-H183 PolarHBondContact O-NE2 3.42Å; E160-H183 PolarHBondContact N-NE2 3.28Å; L179-H183 WeakPolarHBondContact O-CA 3.37Å; L179-H183 VanDerWaalsContact O-CB 3.31Å; L179-H183 WeakPolarHBondContact O-CB 3.43Å; L179-H183 PolarHBondContact O-N 3.02Å; I180-H183 WeakPolarHBondContact O-CB 3.21Å; I180-H183 PolarHBondContact O-N 2.92Å; H183-F185 PolarHBondContact O-N 2.79Å; H183-I186 PolarHBondContact O-N 3.03Å; H183-S187 PolarHBondContact CE1-OG 3.09Å; H183-S187 VanDerWaalsContact O-CB 3.3Å; H183-S187 WeakPolarHBondContact O-CB 3.29Å; H183-S187 PolarHBondContact O-N 3Å; H183-S187 PolarHBondContact O-OG 2.89Å
184	R	91.9	Very high	90	Very high	179 Å²	179	87.6 Å²	87.6	68%	0.675	41%	0.406	S	S	*	.	H	α-helix	trans	-64.3	-40.7	-178.9	-68.8	-177.1	174.7	163.4	1.8	112.4	E160 Y182 F188	E160-R184 IonicContact OE1-CZ 3.59Å; E160-R184 IonicContact OE1-NE 3.06Å; E160-R184 PolarHBondContact OE1-NE 3.34Å; E160-R184 IonicContact OE1-NH2 3.19Å; E160-R184 PolarHBondContact OE1-NH2 3.04Å; Y182-R184 PolarHBondContact O-N 3.11Å; R184-F188 WeakPolarHBondContact O-CB 3.33Å; R184-F188 PolarHBondContact O-N 2.84Å
185	F	95.1	Very high	90.8	Very high	144 Å²	144	84 Å²	84	63%	0.632	39%	0.388	S	S	*	.	H	α-helix	trans	-69.4	-44.8	179	-177.1	-98.6	0	0	0	111.5	Y182 H183 S187 F188 A189	Y182-F185 PolarHBondContact O-N 3.36Å; H183-F185 PolarHBondContact O-N 2.79Å; F185-S187 VanDerWaalsContact C-N 3.33Å; F185-S187 PolarHBondContact O-N 3.14Å; F185-F188 PolarHBondContact O-N 3.18Å; F185-A189 WeakPolarHBondContact O-CB 3.14Å; F185-A189 PolarHBondContact O-N 3.38Å
186	I	94.9	Very high	91.7	Very high	36 Å²	36	79 Å²	79	19%	0.185	37%	0.371	C	S	.	.	H	α-helix	trans	-60.3	-45.6	175.3	-65.2	168.5	0	0	0	110	Y155 F178 L179 Y182 H183 F188 A189 L190	Y155-I186 HydrophobicContact CE1-CB 4.11Å; Y155-I186 HydrophobicContact CE1-CG2 3.7Å; F178-I186 HydrophobicContact CD1-CD1 4.49Å; F178-I186 HydrophobicContact CE1-CD1 3.96Å; L179-I186 HydrophobicContact CD2-CD1 4.06Å; Y182-I186 WeakPolarHBondContact O-CG1 3.23Å; Y182-I186 PolarHBondContact O-N 3.04Å; H183-I186 PolarHBondContact O-N 3.03Å; I186-F188 VanDerWaalsContact C-N 3.34Å; I186-F188 PolarHBondContact O-N 3.17Å; I186-A189 PolarHBondContact O-N 2.92Å; I186-L190 HydrophobicContact CG2-CD1 3.94Å; I186-L190 HydrophobicContact CG2-CG 4.27Å; I186-L190 WeakPolarHBondContact O-CB 3.4Å; I186-L190 VanDerWaalsContact O-CG 3.31Å; I186-L190 WeakPolarHBondContact O-CG 3.39Å; I186-L190 PolarHBondContact O-N 3.25Å
187	S	95.6	Very high	92.4	Very high	8 Å²	8	79.7 Å²	79.7	6%	0.056	37%	0.373	C	S	.	.	H	α-helix	trans	-58.7	-45	177.1	-62.5	0	0	0	0	112.1	Y155 H183 F185 L190 Y191	Y155-S187 VanDerWaalsContact CD1-OG 3.23Å; Y155-S187 WeakPolarHBondContact CD1-OG 3.33Å; Y155-S187 VanDerWaalsContact CE1-OG 3.28Å; Y155-S187 WeakPolarHBondContact CE1-OG 3.27Å; H183-S187 PolarHBondContact CE1-OG 3.09Å; H183-S187 VanDerWaalsContact O-CB 3.3Å; H183-S187 WeakPolarHBondContact O-CB 3.29Å; H183-S187 PolarHBondContact O-N 3Å; H183-S187 PolarHBondContact O-OG 2.89Å; F185-S187 VanDerWaalsContact C-N 3.33Å; F185-S187 PolarHBondContact O-N 3.14Å; S187-L190 PolarHBondContact O-N 3.43Å; S187-Y191 PolarHBondContact O-N 2.8Å
188	F	96.6	Very high	93.1	Very high	129 Å²	129	75.9 Å²	75.9	57%	0.566	36%	0.355	S	S	*	.	H	α-helix	trans	-63.1	-44.3	176.2	179	-104.8	0	0	0	112	R184 F185 I186 Y191 L192	R184-F188 WeakPolarHBondContact O-CB 3.33Å; R184-F188 PolarHBondContact O-N 2.84Å; F185-F188 PolarHBondContact O-N 3.18Å; I186-F188 VanDerWaalsContact C-N 3.34Å; I186-F188 PolarHBondContact O-N 3.17Å; F188-Y191 PolarHBondContact O-N 3.49Å; F188-L192 WeakPolarHBondContact O-CB 3.45Å; F188-L192 PolarHBondContact O-N 2.04Å
189	A	97.8	Very high	93.5	Very high	44 Å²	44	73.4 Å²	73.4	36%	0.364	35%	0.35	S	S	.	.	H	α-helix	trans	-63.6	-42	177.9	0	0	0	0	0	112.4	F185 I186 L192 A193	F185-A189 WeakPolarHBondContact O-CB 3.14Å; F185-A189 PolarHBondContact O-N 3.38Å; I186-A189 PolarHBondContact O-N 2.92Å; A189-L192 PolarHBondContact O-N 3.48Å; A189-A193 WeakPolarHBondContact O-CB 3.41Å; A189-A193 PolarHBondContact O-N 2.85Å
190	L	97.4	Very high	93.8	Very high	51 Å²	51	77.2 Å²	77.2	27%	0.267	37%	0.37	S	S	.	.	H	α-helix	trans	-62.1	-46.1	174.6	-72.8	173.3	0	0	0	111.2	Y148 Y155 I186 S187 L192 A193 G194	Y148-L190 WeakPolarHBondContact CE1-O 3.48Å; Y148-L190 PolarHBondContact OH-O 2.93Å; Y155-L190 HydrophobicContact CD1-CD1 3.99Å; Y155-L190 HydrophobicContact CE1-CD1 4.3Å; I186-L190 HydrophobicContact CG2-CD1 3.94Å; I186-L190 HydrophobicContact CG2-CG 4.27Å; I186-L190 WeakPolarHBondContact O-CB 3.4Å; I186-L190 VanDerWaalsContact O-CG 3.31Å; I186-L190 WeakPolarHBondContact O-CG 3.39Å; I186-L190 PolarHBondContact O-N 3.25Å; S187-L190 PolarHBondContact O-N 3.43Å; L190-L192 VanDerWaalsContact C-N 3.34Å; L190-L192 PolarHBondContact O-N 3.39Å; L190-A193 PolarHBondContact O-N 3.21Å; L190-G194 PolarHBondContact O-N 3.16Å
191	Y	97	Very high	94.1	Very high	91 Å²	91	75.9 Å²	75.9	36%	0.357	37%	0.366	S	S	.	.	H	α-helix	trans	-60	-45.3	175.9	-178.7	-93.8	0	0	0	111.9	F149 S187 F188 A193 G194 F195 H218	F149-Y191 HydrophobicContact CD1-CD2 4.16Å; F149-Y191 HydrophobicContact CD1-CE2 4.22Å; F149-Y191 AromaticContact CE1-CD2 3.98Å; F149-Y191 HydrophobicContact CE1-CD2 3.98Å; F149-Y191 AromaticContact CE1-CE2 3.92Å; F149-Y191 HydrophobicContact CE1-CE2 3.92Å; S187-Y191 PolarHBondContact O-N 2.8Å; F188-Y191 PolarHBondContact O-N 3.49Å; Y191-A193 VanDerWaalsContact C-N 3.35Å; Y191-A193 PolarHBondContact O-N 3Å; Y191-G194 PolarHBondContact O-N 3.28Å; Y191-F195 PolarHBondContact O-N 3.12Å; Y191-H218 AromaticContact CE2-NE2 3.6Å; Y191-H218 AromaticContact CZ-NE2 3.96Å; Y191-H218 PolarHBondContact OH-NE2 3.38Å
192	L	97.4	Very high	94.4	Very high	82 Å²	82	69 Å²	69	43%	0.429	34%	0.344	S	S	.	.	H	α-helix	trans	-63.5	-39.5	178.6	-173.3	62.8	0	0	0	112	F188 A189 L190 G194 F195 C196	F188-L192 WeakPolarHBondContact O-CB 3.45Å; F188-L192 PolarHBondContact O-N 2.04Å; A189-L192 PolarHBondContact O-N 3.48Å; L190-L192 VanDerWaalsContact C-N 3.34Å; L190-L192 PolarHBondContact O-N 3.39Å; L192-G194 VanDerWaalsContact C-N 3.34Å; L192-G194 PolarHBondContact O-N 3.19Å; L192-F195 WeakPolarHBondContact O-CB 3.48Å; L192-F195 PolarHBondContact O-N 3.36Å; L192-C196 PolarHBondContact O-N 3.23Å; L192-C196 PolarHBondContact O-SG 2.65Å; L192-C196 VanDerWaalsContact O-SG 3.33Å
193	A	97.4	Very high	94.3	Very high	43 Å²	43	67.5 Å²	67.5	36%	0.355	34%	0.344	S	S	.	.	H	α-helix	trans	-61.2	-43.4	173.5	0	0	0	0	0	111.5	A189 L190 Y191 F195 C196 M197	A189-A193 WeakPolarHBondContact O-CB 3.41Å; A189-A193 PolarHBondContact O-N 2.85Å; L190-A193 PolarHBondContact O-N 3.21Å; Y191-A193 VanDerWaalsContact C-N 3.35Å; Y191-A193 PolarHBondContact O-N 3Å; A193-F195 VanDerWaalsContact C-N 3.35Å; A193-F195 PolarHBondContact O-N 3.17Å; A193-C196 PolarHBondContact O-N 3.5Å; A193-M197 WeakPolarHBondContact O-CG 3.43Å; A193-M197 PolarHBondContact O-N 3.01Å
194	G	95.8	Very high	94	Very high	0 Å²	0	74.8 Å²	74.8	0%	0	38%	0.375	C	S	.	.	H	α-helix	trans	-58.6	-43.9	172.1	0	0	0	0	0	113.3	F149 L190 Y191 L192 M197 F198	F149-G194 VanDerWaalsContact CZ-C 3.48Å; L190-G194 PolarHBondContact O-N 3.16Å; Y191-G194 PolarHBondContact O-N 3.28Å; L192-G194 VanDerWaalsContact C-N 3.34Å; L192-G194 PolarHBondContact O-N 3.19Å; G194-M197 PolarHBondContact O-N 3.43Å; G194-F198 PolarHBondContact O-N 2.67Å
195	F	95.9	Very high	93.7	Very high	88 Å²	88	75.8 Å²	75.8	39%	0.386	38%	0.384	S	S	.	.	H	α-helix	trans	-63.2	-45.6	176.5	-177.1	-96.9	0	0	0	111.8	Y191 L192 A193 M197 F198 V199 F214	Y191-F195 PolarHBondContact O-N 3.12Å; L192-F195 WeakPolarHBondContact O-CB 3.48Å; L192-F195 PolarHBondContact O-N 3.36Å; A193-F195 VanDerWaalsContact C-N 3.35Å; A193-F195 PolarHBondContact O-N 3.17Å; F195-M197 VanDerWaalsContact C-N 3.35Å; F195-M197 PolarHBondContact O-N 3.17Å; F195-F198 WeakPolarHBondContact O-CB 3.39Å; F195-F198 PolarHBondContact O-N 3.48Å; F195-V199 HydrophobicContact CD1-CG2 4.26Å; F195-V199 HydrophobicContact CE1-CG2 3.88Å; F195-V199 HydrophobicContact CZ-CG2 4.1Å; F195-V199 WeakPolarHBondContact O-CG2 3.4Å; F195-V199 PolarHBondContact O-N 2.89Å; F195-F214 HydrophobicContact CD2-CZ 4.08Å; F195-F214 HydrophobicContact CE2-CZ 4.49Å
196	C	96.1	Very high	93.2	Very high	61 Å²	61	71.4 Å²	71.4	41%	0.412	37%	0.366	S	S	.	.	H	α-helix	trans	-60.3	-43.4	173.8	-69.2	0	0	0	0	111.6	L192 A193 F198 V199 L200	L192-C196 PolarHBondContact O-N 3.23Å; L192-C196 PolarHBondContact O-SG 2.65Å; L192-C196 VanDerWaalsContact O-SG 3.33Å; A193-C196 PolarHBondContact O-N 3.5Å; C196-F198 VanDerWaalsContact C-N 3.31Å; C196-F198 PolarHBondContact O-N 2.98Å; C196-V199 PolarHBondContact O-N 3.14Å; C196-L200 WeakPolarHBondContact O-CB 3.38Å; C196-L200 VanDerWaalsContact O-CG 3.25Å; C196-L200 WeakPolarHBondContact O-CG 3.36Å; C196-L200 PolarHBondContact O-N 2.94Å
197	M	93.8	Very high	92.9	Very high	81 Å²	81	74.6 Å²	74.6	40%	0.399	38%	0.376	S	S	.	.	H	α-helix	trans	-60.6	-39.3	175	-74.3	-172.1	-67.3	0	0	112.3	L145 Y148 A193 G194 F195 S201	L145-M197 HydrophobicContact CD1-CB 4.12Å; Y148-M197 HydrophobicContact CD1-CE 3.79Å; Y148-M197 HydrophobicContact CD2-CE 3.93Å; Y148-M197 HydrophobicContact CE1-CE 3.59Å; Y148-M197 HydrophobicContact CE2-CE 3.73Å; Y148-M197 HydrophobicContact CG-CE 3.95Å; A193-M197 WeakPolarHBondContact O-CG 3.43Å; A193-M197 PolarHBondContact O-N 3.01Å; G194-M197 PolarHBondContact O-N 3.43Å; F195-M197 VanDerWaalsContact C-N 3.35Å; F195-M197 PolarHBondContact O-N 3.17Å; M197-S201 WeakPolarHBondContact O-CB 3.46Å; M197-S201 PolarHBondContact O-N 3.04Å
198	F	93.8	Very high	92.5	Very high	9 Å²	9	77.7 Å²	77.7	4%	0.039	39%	0.387	C	S	.	.	H	α-helix	trans	-60.3	-50.9	173	175.1	-112.2	0	0	0	111.4	L145 G194 F195 C196 L200 S201 L202 Q210 F211 F214	L145-F198 HydrophobicContact CD2-CB 3.81Å; L145-F198 HydrophobicContact CD2-CD2 3.77Å; L145-F198 HydrophobicContact CD2-CG 4.26Å; G194-F198 PolarHBondContact O-N 2.67Å; F195-F198 WeakPolarHBondContact O-CB 3.39Å; F195-F198 PolarHBondContact O-N 3.48Å; C196-F198 VanDerWaalsContact C-N 3.31Å; C196-F198 PolarHBondContact O-N 2.98Å; F198-L200 VanDerWaalsContact C-N 3.31Å; F198-L200 PolarHBondContact O-N 3.39Å; F198-S201 WeakPolarHBondContact O-CA 3.24Å; F198-S201 WeakPolarHBondContact O-CB 3.48Å; F198-S201 PolarHBondContact O-N 3.22Å; F198-S201 PolarHBondContact O-OG 2.83Å; F198-L202 HydrophobicContact CE1-CD2 4.2Å; F198-L202 HydrophobicContact CE2-CD2 4.33Å; F198-L202 HydrophobicContact CZ-CD2 3.91Å; F198-L202 PolarHBondContact O-N 3.47Å; F198-Q210 HydrophobicContact CE2-CB 4.22Å; F198-Q210 HydrophobicContact CZ-CB 4.4Å; F198-F211 HydrophobicContact CE1-CD1 4.22Å; F198-F211 AromaticContact CE1-CE1 3.94Å; F198-F211 HydrophobicContact CE1-CE1 3.94Å; F198-F211 HydrophobicContact CE1-CZ 4.32Å; F198-F211 HydrophobicContact CZ-CD1 4.26Å; F198-F211 HydrophobicContact CZ-CE1 4.37Å; F198-F211 HydrophobicContact CZ-CG 4.5Å; F198-F214 HydrophobicContact CB-CD2 4.22Å; F198-F214 HydrophobicContact CB-CE2 4.05Å; F198-F214 AromaticContact CD1-CD2 3.72Å; F198-F214 HydrophobicContact CD1-CD2 3.72Å; F198-F214 AromaticContact CD1-CE2 3.83Å; F198-F214 HydrophobicContact CD1-CE2 3.83Å; F198-F214 HydrophobicContact CD1-CG 4.18Å; F198-F214 HydrophobicContact CD1-CZ 4.4Å; F198-F214 HydrophobicContact CD2-CB 4.31Å; F198-F214 AromaticContact CD2-CD2 3.61Å; F198-F214 HydrophobicContact CD2-CD2 3.61Å; F198-F214 HydrophobicContact CD2-CE2 4.29Å; F198-F214 HydrophobicContact CD2-CG 4.26Å; F198-F214 HydrophobicContact CE1-CB 4.19Å; F198-F214 HydrophobicContact CE1-CD1 4.37Å; F198-F214 AromaticContact CE1-CD2 3.94Å; F198-F214 HydrophobicContact CE1-CD2 3.94Å; F198-F214 HydrophobicContact CE1-CE2 4.38Å; F198-F214 AromaticContact CE1-CG 3.92Å; F198-F214 HydrophobicContact CE1-CG 3.92Å; F198-F214 HydrophobicContact CE2-CB 3.67Å; F198-F214 AromaticContact CE2-CD2 3.83Å; F198-F214 HydrophobicContact CE2-CD2 3.83Å; F198-F214 HydrophobicContact CE2-CG 4.01Å; F198-F214 AromaticContact CG-CD2 3.55Å; F198-F214 HydrophobicContact CG-CD2 3.55Å; F198-F214 AromaticContact CG-CE2 3.77Å; F198-F214 HydrophobicContact CG-CE2 3.77Å; F198-F214 HydrophobicContact CG-CG 4.34Å; F198-F214 HydrophobicContact CZ-CB 3.6Å; F198-F214 AromaticContact CZ-CD2 3.99Å; F198-F214 HydrophobicContact CZ-CD2 3.99Å; F198-F214 AromaticContact CZ-CG 3.83Å; F198-F214 HydrophobicContact CZ-CG 3.83Å
199	V	93.7	Very high	91.9	Very high	68 Å²	68	72.4 Å²	72.4	41%	0.412	36%	0.364	S	S	.	.	H	α-helix	trans	-59.9	-42	-179.8	174	0	0	0	0	111.3	F195 C196 S201 L202	F195-V199 HydrophobicContact CD1-CG2 4.26Å; F195-V199 HydrophobicContact CE1-CG2 3.88Å; F195-V199 HydrophobicContact CZ-CG2 4.1Å; F195-V199 WeakPolarHBondContact O-CG2 3.4Å; F195-V199 PolarHBondContact O-N 2.89Å; C196-V199 PolarHBondContact O-N 3.14Å; V199-S201 VanDerWaalsContact C-N 3.26Å; V199-S201 PolarHBondContact O-N 3.36Å; V199-L202 HydrophobicContact CG1-CD1 4.44Å; V199-L202 WeakPolarHBondContact O-CB 3.28Å; V199-L202 VanDerWaalsContact O-CG 3.28Å; V199-L202 WeakPolarHBondContact O-CG 3.43Å; V199-L202 PolarHBondContact O-N 2.94Å
200	L	92.1	Very high	91.5	Very high	151 Å²	151	70.8 Å²	70.8	79%	0.791	35%	0.349	S	S	*	.	H	α-helix	trans	-68.7	-23.5	176.4	-67	173.7	0	0	0	113.1	C196 F198 L202	C196-L200 WeakPolarHBondContact O-CB 3.38Å; C196-L200 VanDerWaalsContact O-CG 3.25Å; C196-L200 WeakPolarHBondContact O-CG 3.36Å; C196-L200 PolarHBondContact O-N 2.94Å; F198-L200 VanDerWaalsContact C-N 3.31Å; F198-L200 PolarHBondContact O-N 3.39Å; L200-L202 VanDerWaalsContact C-N 3.27Å; L200-L202 PolarHBondContact O-N 2.92Å
201	S	89.8	Confident	91.2	Very high	29 Å²	29	73.6 Å²	73.6	20%	0.203	36%	0.359	C	S	.	.	T	Hydrogen-bonded Turn	trans	-81.3	-2.1	176.2	77.3	0	0	0	0	113.9	M197 F198 V199 V203 Q210	M197-S201 WeakPolarHBondContact O-CB 3.46Å; M197-S201 PolarHBondContact O-N 3.04Å; F198-S201 WeakPolarHBondContact O-CA 3.24Å; F198-S201 WeakPolarHBondContact O-CB 3.48Å; F198-S201 PolarHBondContact O-N 3.22Å; F198-S201 PolarHBondContact O-OG 2.83Å; V199-S201 VanDerWaalsContact C-N 3.26Å; V199-S201 PolarHBondContact O-N 3.36Å; S201-V203 PolarHBondContact O-N 3.38Å; S201-Q210 PolarHBondContact O-NE2 2.68Å
202	L	90	Very high	90.8	Very high	51 Å²	51	75.8 Å²	75.8	27%	0.267	37%	0.368	S	S	.	.			trans	-67.2	123.9	-175.2	-69.6	175.4	0	0	0	111.8	F198 V199 L200 Y207 Q210 F211	F198-L202 HydrophobicContact CE1-CD2 4.2Å; F198-L202 HydrophobicContact CE2-CD2 4.33Å; F198-L202 HydrophobicContact CZ-CD2 3.91Å; F198-L202 PolarHBondContact O-N 3.47Å; V199-L202 HydrophobicContact CG1-CD1 4.44Å; V199-L202 WeakPolarHBondContact O-CB 3.28Å; V199-L202 VanDerWaalsContact O-CG 3.28Å; V199-L202 WeakPolarHBondContact O-CG 3.43Å; V199-L202 PolarHBondContact O-N 2.94Å; L200-L202 VanDerWaalsContact C-N 3.27Å; L200-L202 PolarHBondContact O-N 2.92Å; L202-Y207 HydrophobicContact CB-CD1 4.27Å; L202-Y207 HydrophobicContact CB-CE1 3.99Å; L202-Y207 HydrophobicContact CD2-CD1 4.38Å; L202-Q210 VanDerWaalsContact CA-OE1 3.26Å; L202-Q210 HydrophobicContact CD2-CB 4.17Å; L202-F211 HydrophobicContact CD2-CE2 4.34Å
203	V	87.7	Confident	90.4	Very high	61 Å²	61	72.1 Å²	72.1	37%	0.37	35%	0.349	S	S	.	.			trans	-110.2	129.2	-179.6	-176.6	0	0	0	0	109.6	S201 H206 Y207	S201-V203 PolarHBondContact O-N 3.38Å; V203-H206 PolarHBondContact O-N 3.46Å; V203-H206 VanDerWaalsContact O-N 3.15Å; V203-Y207 WeakPolarHBondContact O-CD1 2.98Å; V203-Y207 WeakPolarHBondContact O-CE1 3.1Å
204	K	85.1	Confident	90.1	Very high	165 Å²	165	71.6 Å²	71.6	72%	0.717	34%	0.339	S	S	*	.	T	Hydrogen-bonded Turn	trans	-51.5	142.3	174.6	-73.6	-180	-179.2	-176.5	0	110	H206 Y207	K204-H206 VanDerWaalsContact C-N 3.28Å; K204-H206 PolarHBondContact O-N 3.38Å; K204-Y207 VanDerWaalsContact CG-OH 3.24Å; K204-Y207 WeakPolarHBondContact CG-OH 3.43Å
205	K	85	Confident	90	Very high	199 Å²	199	73.9 Å²	73.9	87%	0.865	36%	0.358	S	S	*	.	T	Hydrogen-bonded Turn	trans	77.4	-14.5	-175.2	-49.6	179.8	177.7	-179.1	0	116.4
206	H	84.9	Confident	89.8	Confident	53 Å²	53	71.5 Å²	71.5	25%	0.245	35%	0.346	C	S	.	.			trans	-117.1	14.9	-178.6	-59.9	-62.3	0	0	0	114.5	Y137 L139 V203 K204 R208 L209 Q210	Y137-H206 AromaticContact CD1-CE1 3.53Å; Y137-H206 AromaticContact CD1-ND1 3.67Å; L139-H206 HydrophobicContact CD2-CB 3.98Å; V203-H206 PolarHBondContact O-N 3.46Å; V203-H206 VanDerWaalsContact O-N 3.15Å; K204-H206 VanDerWaalsContact C-N 3.28Å; K204-H206 PolarHBondContact O-N 3.38Å; H206-R208 PolarHBondContact O-N 2.97Å; H206-L209 PolarHBondContact O-N 3.43Å; H206-Q210 WeakPolarHBondContact O-CG 3.41Å; H206-Q210 PolarHBondContact O-N 3.31Å
207	Y	88	Confident	89.7	Confident	102 Å²	102	68.7 Å²	68.7	40%	0.4	33%	0.327	S	S	.	.	H	α-helix	trans	-55.2	-52.9	-175.9	-60	-42.2	0	0	0	113.5	L202 V203 K204 L209 Q210 F211	L202-Y207 HydrophobicContact CB-CD1 4.27Å; L202-Y207 HydrophobicContact CB-CE1 3.99Å; L202-Y207 HydrophobicContact CD2-CD1 4.38Å; V203-Y207 WeakPolarHBondContact O-CD1 2.98Å; V203-Y207 WeakPolarHBondContact O-CE1 3.1Å; K204-Y207 VanDerWaalsContact CG-OH 3.24Å; K204-Y207 WeakPolarHBondContact CG-OH 3.43Å; Y207-L209 PolarHBondContact O-N 2.97Å; Y207-Q210 PolarHBondContact O-N 3.45Å; Y207-Q210 VanDerWaalsContact O-N 3.11Å; Y207-F211 VanDerWaalsContact O-CD2 3.24Å; Y207-F211 WeakPolarHBondContact O-CD2 3.38Å; Y207-F211 PolarHBondContact O-N 2.96Å
208	R	86.9	Confident	89.8	Confident	74 Å²	74	67 Å²	67	28%	0.279	32%	0.318	S	S	.	.	H	α-helix	trans	-53.8	-45.3	-179.9	-66.4	-167.2	-169.3	169.6	8.9	111.3	Y47 H206 F211 Y212	Y47-R208 VanDerWaalsContact CE1-CZ 3.45Å; Y47-R208 VanDerWaalsContact CE1-NE 3.27Å; Y47-R208 PolarHBondContact O-NH2 3.34Å; H206-R208 PolarHBondContact O-N 2.97Å; R208-F211 PolarHBondContact O-N 3.47Å; R208-Y212 HydrophobicContact CB-CE2 4.11Å; R208-Y212 WeakPolarHBondContact O-CD2 3.3Å; R208-Y212 PolarHBondContact O-N 2.99Å
209	L	84.9	Confident	89.8	Confident	17 Å²	17	70.4 Å²	70.4	9%	0.089	34%	0.339	C	S	.	.	H	α-helix	trans	-63.7	-45.7	179.1	-178.9	59.3	0	0	0	112.5	Y134 Y137 L139 H206 Y207 F211 Y212 M213	Y134-L209 HydrophobicContact CD1-CD1 3.18Å; Y134-L209 HydrophobicContact CD2-CD1 4.2Å; Y134-L209 HydrophobicContact CE1-CD1 3.67Å; Y134-L209 HydrophobicContact CG-CD1 3.49Å; Y134-L209 VanDerWaalsContact CG-CD1 3.49Å; Y137-L209 HydrophobicContact CD1-CD2 4.4Å; Y137-L209 HydrophobicContact CD2-CD2 3.27Å; Y137-L209 HydrophobicContact CE2-CD2 4.03Å; Y137-L209 HydrophobicContact CG-CD2 3.48Å; Y137-L209 VanDerWaalsContact CG-CD2 3.48Å; L139-L209 HydrophobicContact CD1-CD2 3.71Å; L139-L209 HydrophobicContact CD1-CG 3.93Å; H206-L209 PolarHBondContact O-N 3.43Å; Y207-L209 PolarHBondContact O-N 2.97Å; L209-F211 VanDerWaalsContact C-N 3.32Å; L209-F211 PolarHBondContact O-N 3.06Å; L209-Y212 PolarHBondContact O-N 3.19Å; L209-M213 HydrophobicContact CD1-CE 4.1Å; L209-M213 HydrophobicContact CD1-CG 4.5Å; L209-M213 HydrophobicContact CD2-CE 4.36Å; L209-M213 HydrophobicContact CG-CE 4.14Å; L209-M213 WeakPolarHBondContact O-CB 3.19Å; L209-M213 WeakPolarHBondContact O-CG 3.31Å; L209-M213 PolarHBondContact O-N 3.13Å
210	Q	88.5	Confident	89.8	Confident	10 Å²	10	67.4 Å²	67.4	5%	0.047	32%	0.321	C	S	.	.	H	α-helix	trans	-62.6	-38.7	177.4	-71.3	-179.8	-43.5	0	0	111.8	L139 F198 S201 L202 H206 Y207 M213 F214	L139-Q210 HydrophobicContact CD1-CG 4.06Å; L139-Q210 HydrophobicContact CD2-CG 4.04Å; F198-Q210 HydrophobicContact CE2-CB 4.22Å; F198-Q210 HydrophobicContact CZ-CB 4.4Å; S201-Q210 PolarHBondContact O-NE2 2.68Å; L202-Q210 VanDerWaalsContact CA-OE1 3.26Å; L202-Q210 HydrophobicContact CD2-CB 4.17Å; H206-Q210 WeakPolarHBondContact O-CG 3.41Å; H206-Q210 PolarHBondContact O-N 3.31Å; Y207-Q210 PolarHBondContact O-N 3.45Å; Y207-Q210 VanDerWaalsContact O-N 3.11Å; Q210-M213 PolarHBondContact O-N 3.08Å; Q210-F214 VanDerWaalsContact O-CB 3.3Å; Q210-F214 WeakPolarHBondContact O-CB 3.44Å; Q210-F214 PolarHBondContact O-N 3.4Å
211	F	91.1	Very high	90	Very high	110 Å²	110	60.4 Å²	60.4	48%	0.482	29%	0.285	S	S	.	.	H	α-helix	trans	-68.8	-39.4	173.9	-82.3	-75.9	0	0	0	112.8	F198 L202 Y207 R208 L209 M213 F214 A215	F198-F211 HydrophobicContact CE1-CD1 4.22Å; F198-F211 AromaticContact CE1-CE1 3.94Å; F198-F211 HydrophobicContact CE1-CE1 3.94Å; F198-F211 HydrophobicContact CE1-CZ 4.32Å; F198-F211 HydrophobicContact CZ-CD1 4.26Å; F198-F211 HydrophobicContact CZ-CE1 4.37Å; F198-F211 HydrophobicContact CZ-CG 4.5Å; L202-F211 HydrophobicContact CD2-CE2 4.34Å; Y207-F211 VanDerWaalsContact O-CD2 3.24Å; Y207-F211 WeakPolarHBondContact O-CD2 3.38Å; Y207-F211 PolarHBondContact O-N 2.96Å; R208-F211 PolarHBondContact O-N 3.47Å; L209-F211 VanDerWaalsContact C-N 3.32Å; L209-F211 PolarHBondContact O-N 3.06Å; F211-M213 VanDerWaalsContact C-N 3.34Å; F211-M213 PolarHBondContact O-N 3.27Å; F211-F214 PolarHBondContact O-N 3.07Å; F211-A215 WeakPolarHBondContact O-CB 3.26Å; F211-A215 PolarHBondContact O-N 3.34Å
212	Y	89.6	Confident	90.2	Very high	137 Å²	137	64.3 Å²	64.3	54%	0.537	30%	0.303	S	S	.	.	H	α-helix	trans	-61.7	-43.4	173.1	-70.5	-45.9	0	0	0	111.9	R208 L209 A215 W216	R208-Y212 HydrophobicContact CB-CE2 4.11Å; R208-Y212 WeakPolarHBondContact O-CD2 3.3Å; R208-Y212 PolarHBondContact O-N 2.99Å; L209-Y212 PolarHBondContact O-N 3.19Å; Y212-A215 PolarHBondContact O-N 2.99Å; Y212-W216 VanDerWaalsContact O-CB 3.26Å; Y212-W216 WeakPolarHBondContact O-CB 3.4Å; Y212-W216 PolarHBondContact O-N 3.33Å
213	M	87.7	Confident	90.3	Very high	6 Å²	6	64.7 Å²	64.7	3%	0.03	30%	0.304	C	S	.	.	H	α-helix	trans	-63.5	-42.1	175.1	-83.3	-170.3	-177.2	0	0	112.5	Y134 L139 F142 L209 Q210 F211 W216 T217	Y134-M213 HydrophobicContact CD2-CE 4.13Å; Y134-M213 HydrophobicContact CD2-CG 4.39Å; Y134-M213 HydrophobicContact CG-CE 3.94Å; L139-M213 HydrophobicContact CD1-CE 3.78Å; L139-M213 HydrophobicContact CD1-SD 3.59Å; L139-M213 VanDerWaalsContact CD1-SD 3.59Å; F142-M213 HydrophobicContact CB-SD 4.25Å; F142-M213 HydrophobicContact CD1-CE 4.49Å; F142-M213 HydrophobicContact CD1-SD 3.77Å; F142-M213 HydrophobicContact CD2-CB 3.8Å; F142-M213 HydrophobicContact CD2-CG 4.24Å; F142-M213 HydrophobicContact CD2-SD 3.76Å; F142-M213 HydrophobicContact CE1-CG 4.31Å; F142-M213 HydrophobicContact CE1-SD 4.04Å; F142-M213 HydrophobicContact CE2-CB 3.43Å; F142-M213 VanDerWaalsContact CE2-CB 3.43Å; F142-M213 HydrophobicContact CE2-CG 3.98Å; F142-M213 HydrophobicContact CE2-SD 4.08Å; F142-M213 HydrophobicContact CG-SD 3.61Å; F142-M213 HydrophobicContact CZ-CB 3.87Å; F142-M213 HydrophobicContact CZ-CG 3.98Å; F142-M213 HydrophobicContact CZ-SD 4.18Å; L209-M213 HydrophobicContact CD1-CE 4.1Å; L209-M213 HydrophobicContact CD1-CG 4.5Å; L209-M213 HydrophobicContact CD2-CE 4.36Å; L209-M213 HydrophobicContact CG-CE 4.14Å; L209-M213 WeakPolarHBondContact O-CB 3.19Å; L209-M213 WeakPolarHBondContact O-CG 3.31Å; L209-M213 PolarHBondContact O-N 3.13Å; Q210-M213 PolarHBondContact O-N 3.08Å; F211-M213 VanDerWaalsContact C-N 3.34Å; F211-M213 PolarHBondContact O-N 3.27Å; M213-W216 WeakPolarHBondContact O-CB 3.3Å; M213-W216 PolarHBondContact O-N 3.19Å; M213-T217 PolarHBondContact O-N 3.46Å; M213-T217 PolarHBondContact O-OG1 3.38Å
214	F	92.3	Very high	90.6	Very high	32 Å²	32	61.8 Å²	61.8	14%	0.14	29%	0.286	C	S	.	.	H	α-helix	trans	-62	-47.3	175.2	-175.8	-100	0	0	0	111.5	F149 F195 F198 Q210 F211 W216 T217 H218	F149-F214 HydrophobicContact CE2-CD2 4.29Å; F149-F214 AromaticContact CE2-CE2 3.77Å; F149-F214 HydrophobicContact CE2-CE2 3.77Å; F149-F214 AromaticContact CZ-CE2 3.73Å; F149-F214 HydrophobicContact CZ-CE2 3.73Å; F149-F214 HydrophobicContact CZ-CZ 4.43Å; F195-F214 HydrophobicContact CD2-CZ 4.08Å; F195-F214 HydrophobicContact CE2-CZ 4.49Å; F198-F214 HydrophobicContact CB-CD2 4.22Å; F198-F214 HydrophobicContact CB-CE2 4.05Å; F198-F214 AromaticContact CD1-CD2 3.72Å; F198-F214 HydrophobicContact CD1-CD2 3.72Å; F198-F214 AromaticContact CD1-CE2 3.83Å; F198-F214 HydrophobicContact CD1-CE2 3.83Å; F198-F214 HydrophobicContact CD1-CG 4.18Å; F198-F214 HydrophobicContact CD1-CZ 4.4Å; F198-F214 HydrophobicContact CD2-CB 4.31Å; F198-F214 AromaticContact CD2-CD2 3.61Å; F198-F214 HydrophobicContact CD2-CD2 3.61Å; F198-F214 HydrophobicContact CD2-CE2 4.29Å; F198-F214 HydrophobicContact CD2-CG 4.26Å; F198-F214 HydrophobicContact CE1-CB 4.19Å; F198-F214 HydrophobicContact CE1-CD1 4.37Å; F198-F214 AromaticContact CE1-CD2 3.94Å; F198-F214 HydrophobicContact CE1-CD2 3.94Å; F198-F214 HydrophobicContact CE1-CE2 4.38Å; F198-F214 AromaticContact CE1-CG 3.92Å; F198-F214 HydrophobicContact CE1-CG 3.92Å; F198-F214 HydrophobicContact CE2-CB 3.67Å; F198-F214 AromaticContact CE2-CD2 3.83Å; F198-F214 HydrophobicContact CE2-CD2 3.83Å; F198-F214 HydrophobicContact CE2-CG 4.01Å; F198-F214 AromaticContact CG-CD2 3.55Å; F198-F214 HydrophobicContact CG-CD2 3.55Å; F198-F214 AromaticContact CG-CE2 3.77Å; F198-F214 HydrophobicContact CG-CE2 3.77Å; F198-F214 HydrophobicContact CG-CG 4.34Å; F198-F214 HydrophobicContact CZ-CB 3.6Å; F198-F214 AromaticContact CZ-CD2 3.99Å; F198-F214 HydrophobicContact CZ-CD2 3.99Å; F198-F214 AromaticContact CZ-CG 3.83Å; F198-F214 HydrophobicContact CZ-CG 3.83Å; Q210-F214 VanDerWaalsContact O-CB 3.3Å; Q210-F214 WeakPolarHBondContact O-CB 3.44Å; Q210-F214 PolarHBondContact O-N 3.4Å; F211-F214 PolarHBondContact O-N 3.07Å; F214-W216 VanDerWaalsContact C-N 3.35Å; F214-W216 PolarHBondContact O-N 3.18Å; F214-T217 PolarHBondContact O-N 3.26Å; F214-H218 AromaticContact CD1-ND1 3.87Å; F214-H218 AromaticContact CD2-CE1 3.72Å; F214-H218 AromaticContact CE1-CE1 3.58Å; F214-H218 AromaticContact CE1-ND1 3.73Å; F214-H218 AromaticContact CE2-CE1 3.22Å; F214-H218 WeakPolarHBondContact CE2-CE1 3.42Å; F214-H218 AromaticContact CE2-ND1 3.92Å; F214-H218 AromaticContact CZ-CE1 3.12Å; F214-H218 WeakPolarHBondContact CZ-CE1 3.28Å; F214-H218 AromaticContact CZ-ND1 3.75Å; F214-H218 AromaticContact CZ-NE2 3.69Å; F214-H218 PolarHBondContact O-N 3.3Å; F214-H218 VanDerWaalsContact O-N 3.08Å; F214-H218 PolarHBondContact O-ND1 3.02Å
215	A	93.4	Very high	91.1	Very high	48 Å²	48	53.9 Å²	53.9	40%	0.397	25%	0.252	S	S	.	.	H	α-helix	trans	-61.5	-43	175	0	0	0	0	0	111.6	F211 Y212 T217 H218 V219	F211-A215 WeakPolarHBondContact O-CB 3.26Å; F211-A215 PolarHBondContact O-N 3.34Å; Y212-A215 PolarHBondContact O-N 2.99Å; A215-T217 VanDerWaalsContact C-N 3.34Å; A215-T217 PolarHBondContact O-N 3.35Å; A215-H218 PolarHBondContact O-N 2.9Å; A215-V219 WeakPolarHBondContact O-CB 3.31Å; A215-V219 WeakPolarHBondContact O-CG2 3.27Å; A215-V219 PolarHBondContact O-N 3.37Å
216	W	91	Very high	91.5	Very high	37 Å²	37	45.9 Å²	45.9	14%	0.14	22%	0.22	C	C	.	.	H	α-helix	trans	-56.2	-47.1	175.8	-175.4	-88.6	0	0	0	111.9	I126 I129 Y212 M213 F214 T220 F377 F381	I126-W216 HydrophobicContact CG2-CZ2 4.03Å; I126-W216 PolarHBondContact O-NE1 2.92Å; I126-W216 VanDerWaalsContact O-NE1 3.15Å; I129-W216 HydrophobicContact CG2-CZ2 4.5Å; Y212-W216 VanDerWaalsContact O-CB 3.26Å; Y212-W216 WeakPolarHBondContact O-CB 3.4Å; Y212-W216 PolarHBondContact O-N 3.33Å; M213-W216 WeakPolarHBondContact O-CB 3.3Å; M213-W216 PolarHBondContact O-N 3.19Å; F214-W216 VanDerWaalsContact C-N 3.35Å; F214-W216 PolarHBondContact O-N 3.18Å; W216-T220 VanDerWaalsContact O-CB 3.3Å; W216-T220 WeakPolarHBondContact O-CB 3.43Å; W216-T220 PolarHBondContact O-N 3.27Å; W216-T220 PolarHBondContact O-OG1 3.24Å; W216-F377 HydrophobicContact CH2-CE1 4.22Å; W216-F377 AromaticContact CH2-CE2 3.56Å; W216-F377 HydrophobicContact CH2-CE2 3.56Å; W216-F377 AromaticContact CH2-CZ 3.15Å; W216-F377 HydrophobicContact CH2-CZ 3.15Å; W216-F377 HydrophobicContact CZ2-CE2 4.34Å; W216-F377 AromaticContact CZ2-CZ 3.63Å; W216-F377 HydrophobicContact CZ2-CZ 3.63Å; W216-F377 AromaticContact CZ3-CE2 3.87Å; W216-F377 HydrophobicContact CZ3-CE2 3.87Å; W216-F377 AromaticContact CZ3-CZ 3.95Å; W216-F377 HydrophobicContact CZ3-CZ 3.95Å; W216-F381 HydrophobicContact CH2-CD2 4.41Å; W216-F381 HydrophobicContact CH2-CE1 4.32Å; W216-F381 AromaticContact CH2-CE2 3.72Å; W216-F381 HydrophobicContact CH2-CE2 3.72Å; W216-F381 AromaticContact CH2-CZ 3.68Å; W216-F381 HydrophobicContact CH2-CZ 3.68Å; W216-F381 HydrophobicContact CZ3-CE1 4.32Å; W216-F381 AromaticContact CZ3-CE2 3.87Å; W216-F381 HydrophobicContact CZ3-CE2 3.87Å; W216-F381 AromaticContact CZ3-CZ 3.52Å; W216-F381 HydrophobicContact CZ3-CZ 3.52Å
217	T	94.1	Very high	91.9	Very high	2 Å²	2	44.7 Å²	44.7	1%	0.012	22%	0.215	C	C	.	.	H	α-helix	trans	-61	-46.8	176.5	-64.6	0	0	0	0	111.3	F123 S146 F149 M213 F214 A215 T220 L221	F123-T217 HydrophobicContact CZ-CG2 4.43Å; S146-T217 PolarHBondContact OG-OG1 3.43Å; F149-T217 HydrophobicContact CB-CG2 4.3Å; F149-T217 HydrophobicContact CD2-CG2 4.49Å; M213-T217 PolarHBondContact O-N 3.46Å; M213-T217 PolarHBondContact O-OG1 3.38Å; F214-T217 PolarHBondContact O-N 3.26Å; A215-T217 VanDerWaalsContact C-N 3.34Å; A215-T217 PolarHBondContact O-N 3.35Å; T217-T220 PolarHBondContact O-N 3.42Å; T217-L221 HydrophobicContact CG2-CD1 3.93Å; T217-L221 HydrophobicContact CG2-CG 4.46Å; T217-L221 VanDerWaalsContact O-CG 3.23Å; T217-L221 WeakPolarHBondContact O-CG 3.46Å; T217-L221 PolarHBondContact O-N 3.42Å
218	H	95.6	Very high	92.3	Very high	45 Å²	45	40.1 Å²	40.1	21%	0.208	20%	0.198	C	C	.	.	H	α-helix	trans	-67.4	-41.8	-178.8	-74	74.5	0	0	0	113.2	Y191 F214 A215 T220 L221 L222	Y191-H218 AromaticContact CE2-NE2 3.6Å; Y191-H218 AromaticContact CZ-NE2 3.96Å; Y191-H218 PolarHBondContact OH-NE2 3.38Å; F214-H218 AromaticContact CD1-ND1 3.87Å; F214-H218 AromaticContact CD2-CE1 3.72Å; F214-H218 AromaticContact CE1-CE1 3.58Å; F214-H218 AromaticContact CE1-ND1 3.73Å; F214-H218 AromaticContact CE2-CE1 3.22Å; F214-H218 WeakPolarHBondContact CE2-CE1 3.42Å; F214-H218 AromaticContact CE2-ND1 3.92Å; F214-H218 AromaticContact CZ-CE1 3.12Å; F214-H218 WeakPolarHBondContact CZ-CE1 3.28Å; F214-H218 AromaticContact CZ-ND1 3.75Å; F214-H218 AromaticContact CZ-NE2 3.69Å; F214-H218 PolarHBondContact O-N 3.3Å; F214-H218 VanDerWaalsContact O-N 3.08Å; F214-H218 PolarHBondContact O-ND1 3.02Å; A215-H218 PolarHBondContact O-N 2.9Å; H218-T220 VanDerWaalsContact C-N 3.33Å; H218-L221 PolarHBondContact O-N 3.15Å; H218-L222 WeakPolarHBondContact O-CB 3.34Å; H218-L222 PolarHBondContact O-N 3.16Å
219	V	94.1	Very high	92.7	Very high	81 Å²	81	37.1 Å²	37.1	49%	0.491	19%	0.187	S	C	.	.	H	α-helix	trans	-63.5	-41.5	174.3	171.6	0	0	0	0	110.5	A215 L222 I223	A215-V219 WeakPolarHBondContact O-CB 3.31Å; A215-V219 WeakPolarHBondContact O-CG2 3.27Å; A215-V219 PolarHBondContact O-N 3.37Å; V219-L222 PolarHBondContact O-N 3.4Å; V219-I223 HydrophobicContact CG1-CD1 3.81Å; V219-I223 WeakPolarHBondContact O-CG1 3.48Å; V219-I223 PolarHBondContact O-N 2.96Å
220	T	93.7	Very high	93.1	Very high	5 Å²	5	37.4 Å²	37.4	3%	0.031	19%	0.188	C	C	.	.	H	α-helix	trans	-61.9	-45.5	175.6	-55.3	0	0	0	0	110.6	F123 I126 I127 W216 T217 H218 L222 I223 T224	F123-T220 HydrophobicContact CD2-CG2 3.56Å; F123-T220 HydrophobicContact CE2-CG2 4.01Å; F123-T220 HydrophobicContact CG-CG2 4.43Å; I126-T220 HydrophobicContact CB-CG2 3.77Å; I126-T220 HydrophobicContact CD1-CG2 3.93Å; I126-T220 HydrophobicContact CG1-CG2 4.48Å; I126-T220 HydrophobicContact CG2-CG2 3.68Å; I126-T220 WeakPolarHBondContact CG2-OG1 3.33Å; I127-T220 HydrophobicContact CD1-CG2 4.31Å; I127-T220 HydrophobicContact CG1-CG2 4.49Å; W216-T220 VanDerWaalsContact O-CB 3.3Å; W216-T220 WeakPolarHBondContact O-CB 3.43Å; W216-T220 PolarHBondContact O-N 3.27Å; W216-T220 PolarHBondContact O-OG1 3.24Å; T217-T220 PolarHBondContact O-N 3.42Å; H218-T220 VanDerWaalsContact C-N 3.33Å; T220-L222 PolarHBondContact O-N 3.35Å; T220-I223 PolarHBondContact O-N 3.43Å; T220-T224 HydrophobicContact CG2-CG2 4.08Å; T220-T224 WeakPolarHBondContact O-CB 3.3Å; T220-T224 WeakPolarHBondContact O-CG2 3.43Å; T220-T224 PolarHBondContact O-N 2.95Å; T220-T224 PolarHBondContact O-OG1 3Å
221	L	95.9	Very high	93.4	Very high	5 Å²	5	38 Å²	38	3%	0.026	19%	0.193	C	C	.	.	H	α-helix	trans	-61.5	-43.4	177.8	-69.8	167.9	0	0	0	112.2	F123 F149 L150 V153 T217 H218 I223 T224 V225	F123-L221 HydrophobicContact CD2-CD2 3.87Å; F123-L221 HydrophobicContact CD2-CG 4.44Å; F123-L221 HydrophobicContact CE2-CD2 3.42Å; F123-L221 VanDerWaalsContact CE2-CD2 3.42Å; F123-L221 HydrophobicContact CE2-CG 3.76Å; F123-L221 HydrophobicContact CZ-CD2 4.08Å; F149-L221 HydrophobicContact CB-CD1 3.62Å; L150-L221 HydrophobicContact CB-CD2 4.06Å; L150-L221 HydrophobicContact CD1-CD2 3.58Å; L150-L221 HydrophobicContact CG-CD2 4.44Å; V153-L221 HydrophobicContact CG2-CD1 4.03Å; T217-L221 HydrophobicContact CG2-CD1 3.93Å; T217-L221 HydrophobicContact CG2-CG 4.46Å; T217-L221 VanDerWaalsContact O-CG 3.23Å; T217-L221 WeakPolarHBondContact O-CG 3.46Å; T217-L221 PolarHBondContact O-N 3.42Å; H218-L221 PolarHBondContact O-N 3.15Å; L221-I223 VanDerWaalsContact C-N 3.32Å; L221-I223 PolarHBondContact O-N 3.48Å; L221-T224 PolarHBondContact O-N 3.34Å; L221-V225 HydrophobicContact CD2-CG2 3.79Å; L221-V225 WeakPolarHBondContact O-CA 3.37Å; L221-V225 VanDerWaalsContact O-CB 3.32Å; L221-V225 WeakPolarHBondContact O-CB 3.45Å; L221-V225 PolarHBondContact O-N 2.93Å
222	L	94.1	Very high	93.6	Very high	111 Å²	111	32.8 Å²	32.8	58%	0.581	17%	0.17	S	C	*	.	H	α-helix	trans	-59	-44.2	175.4	178.9	64.9	0	0	0	111.3	H218 V219 T220 T226	H218-L222 WeakPolarHBondContact O-CB 3.34Å; H218-L222 PolarHBondContact O-N 3.16Å; V219-L222 PolarHBondContact O-N 3.4Å; T220-L222 PolarHBondContact O-N 3.35Å; L222-T226 WeakPolarHBondContact O-CB 3.29Å; L222-T226 PolarHBondContact O-OG1 3.07Å
223	I	92.1	Very high	93.6	Very high	58 Å²	58	27.9 Å²	27.9	30%	0.297	15%	0.151	S	C	.	.	H	α-helix	trans	-75	-41.1	-179.2	-66.1	169.7	0	0	0	111.5	V219 T220 L221 Q227 Y404	V219-I223 HydrophobicContact CG1-CD1 3.81Å; V219-I223 WeakPolarHBondContact O-CG1 3.48Å; V219-I223 PolarHBondContact O-N 2.96Å; T220-I223 PolarHBondContact O-N 3.43Å; L221-I223 VanDerWaalsContact C-N 3.32Å; L221-I223 PolarHBondContact O-N 3.48Å; I223-Q227 VanDerWaalsContact O-CB 3.27Å; I223-Q227 WeakPolarHBondContact O-CB 3.44Å; I223-Q227 WeakPolarHBondContact O-CG 3.46Å; I223-Y404 HydrophobicContact CG2-CD2 3.76Å; I223-Y404 HydrophobicContact CG2-CE2 3.92Å
224	T	94	Very high	93.9	Very high	0 Å²	0	27.8 Å²	27.8	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-87.8	-47.8	-172.9	61.5	0	0	0	0	112.7	C122 I126 T220 L221 S228	C122-T224 HydrophobicContact CB-CG2 4.22Å; I126-T224 HydrophobicContact CD1-CG2 3.95Å; T220-T224 HydrophobicContact CG2-CG2 4.08Å; T220-T224 WeakPolarHBondContact O-CB 3.3Å; T220-T224 WeakPolarHBondContact O-CG2 3.43Å; T220-T224 PolarHBondContact O-N 2.95Å; T220-T224 PolarHBondContact O-OG1 3Å; L221-T224 PolarHBondContact O-N 3.34Å; T224-S228 WeakPolarHBondContact O-CB 3.37Å; T224-S228 PolarHBondContact O-N 2.95Å; T224-S228 VanDerWaalsContact O-N 3.11Å; T224-S228 PolarHBondContact O-OG 3.39Å; T224-S228 VanDerWaalsContact O-OG 3.09Å
225	V	95.5	Very high	93.9	Very high	0 Å²	0	26.3 Å²	26.3	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-81.4	-41.6	-170.7	-171.8	0	0	0	0	111.5	Q119 L150 V153 F157 Y158 L221 Q227 S228 H229	Q119-V225 HydrophobicContact CG-CG2 4.43Å; L150-V225 HydrophobicContact CD1-CG2 3.8Å; V153-V225 HydrophobicContact CG1-CB 3.98Å; V153-V225 HydrophobicContact CG1-CG1 3.8Å; V153-V225 HydrophobicContact CG1-CG2 4.33Å; F157-V225 HydrophobicContact CD2-CG1 4.05Å; Y158-V225 HydrophobicContact CE2-CG1 4.31Å; L221-V225 HydrophobicContact CD2-CG2 3.79Å; L221-V225 WeakPolarHBondContact O-CA 3.37Å; L221-V225 VanDerWaalsContact O-CB 3.32Å; L221-V225 WeakPolarHBondContact O-CB 3.45Å; L221-V225 PolarHBondContact O-N 2.93Å; V225-Q227 VanDerWaalsContact C-N 3.29Å; V225-Q227 PolarHBondContact O-N 3.02Å; V225-S228 WeakPolarHBondContact CA-OG 3.4Å; V225-S228 PolarHBondContact O-N 2.98Å; V225-S228 PolarHBondContact O-OG 2.86Å; V225-H229 VanDerWaalsContact O-CB 3.3Å; V225-H229 WeakPolarHBondContact O-CB 3.42Å; V225-H229 PolarHBondContact O-N 3.47Å
226	T	93.8	Very high	93.7	Very high	30 Å²	30	24.2 Å²	24.2	18%	0.184	13%	0.127	C	C	.	.	H	α-helix	trans	-62.4	-41.9	175.7	-53	0	0	0	0	110.3	L222 H229 L230	L222-T226 WeakPolarHBondContact O-CB 3.29Å; L222-T226 PolarHBondContact O-OG1 3.07Å; T226-H229 WeakPolarHBondContact O-CB 2.9Å; T226-H229 PolarHBondContact O-N 3.3Å; T226-L230 HydrophobicContact CG2-CD1 4.48Å; T226-L230 VanDerWaalsContact O-CG 3.31Å; T226-L230 WeakPolarHBondContact O-CG 3.21Å; T226-L230 PolarHBondContact O-N 3.27Å
227	Q	94.3	Very high	93.6	Very high	29 Å²	29	24.8 Å²	24.8	14%	0.136	13%	0.131	C	C	.	.	H	α-helix	trans	-67.4	-43.9	179.5	-59.6	-58	-30.9	0	0	112.4	I223 V225 H229 L230 V231 Y404 T408	I223-Q227 VanDerWaalsContact O-CB 3.27Å; I223-Q227 WeakPolarHBondContact O-CB 3.44Å; I223-Q227 WeakPolarHBondContact O-CG 3.46Å; V225-Q227 VanDerWaalsContact C-N 3.29Å; V225-Q227 PolarHBondContact O-N 3.02Å; Q227-H229 VanDerWaalsContact C-N 3.29Å; Q227-H229 PolarHBondContact O-N 2.98Å; Q227-L230 PolarHBondContact O-N 3.01Å; Q227-V231 VanDerWaalsContact O-CG2 3.31Å; Q227-V231 WeakPolarHBondContact O-CG2 3.34Å; Q227-V231 PolarHBondContact O-N 3.29Å; Q227-Y404 HydrophobicContact CB-CD1 3.69Å; Q227-Y404 HydrophobicContact CB-CE1 4.21Å; Q227-Y404 HydrophobicContact CB-CG 4.15Å; Q227-Y404 HydrophobicContact CG-CD1 4.19Å; Q227-Y404 HydrophobicContact CG-CG 4.13Å; Q227-Y404 PolarHBondContact OE1-O 3.34Å; Q227-T408 PolarHBondContact NE2-OG1 2.97Å; Q227-T408 PolarHBondContact OE1-OG1 3.45Å
228	S	95.1	Very high	93.4	Very high	6 Å²	6	24.7 Å²	24.7	4%	0.042	13%	0.13	C	C	.	.	H	α-helix	trans	-63.3	-35.3	175.5	59.6	0	0	0	0	112.6	Q119 Y158 T224 V225 V231 I232	Q119-S228 WeakPolarHBondContact CG-OG 3.27Å; Q119-S228 PolarHBondContact OE1-OG 3.28Å; Y158-S228 VanDerWaalsContact OH-CB 3.3Å; Y158-S228 WeakPolarHBondContact OH-CB 3.31Å; Y158-S228 PolarHBondContact OH-OG 3.44Å; T224-S228 WeakPolarHBondContact O-CB 3.37Å; T224-S228 PolarHBondContact O-N 2.95Å; T224-S228 VanDerWaalsContact O-N 3.11Å; T224-S228 PolarHBondContact O-OG 3.39Å; T224-S228 VanDerWaalsContact O-OG 3.09Å; V225-S228 WeakPolarHBondContact CA-OG 3.4Å; V225-S228 PolarHBondContact O-N 2.98Å; V225-S228 PolarHBondContact O-OG 2.86Å; S228-V231 PolarHBondContact O-N 2.88Å; S228-I232 WeakPolarHBondContact O-CG1 3.31Å; S228-I232 PolarHBondContact O-N 2.79Å; S228-I232 VanDerWaalsContact O-N 3.07Å
229	H	94.9	Very high	93.3	Very high	11 Å²	11	22.6 Å²	22.6	5%	0.051	12%	0.121	C	C	.	.	H	α-helix	trans	-62.8	-47.6	173.1	173.5	70.7	0	0	0	111.8	F157 Y158 T161 V225 T226 Q227 V231 I232 Q233	F157-H229 HydrophobicContact CB-CB 4.14Å; F157-H229 HydrophobicContact CD1-CB 4.34Å; F157-H229 AromaticContact CD1-CD2 3.5Å; F157-H229 VanDerWaalsContact CD1-CD2 3.5Å; F157-H229 WeakPolarHBondContact CD1-CD2 3.39Å; F157-H229 AromaticContact CD1-CG 3.79Å; F157-H229 AromaticContact CD1-NE2 3.72Å; F157-H229 HydrophobicContact CG-CB 4.31Å; F157-H229 PolarHBondContact O-CE1 3.16Å; F157-H229 VanDerWaalsContact O-CE1 3.3Å; F157-H229 PolarHBondContact O-ND1 3.46Å; Y158-H229 PolarHBondContact OH-N 3.28Å; T161-H229 PolarHBondContact OG1-CE1 3.4Å; T161-H229 PolarHBondContact OG1-ND1 3.44Å; V225-H229 VanDerWaalsContact O-CB 3.3Å; V225-H229 WeakPolarHBondContact O-CB 3.42Å; V225-H229 PolarHBondContact O-N 3.47Å; T226-H229 WeakPolarHBondContact O-CB 2.9Å; T226-H229 PolarHBondContact O-N 3.3Å; Q227-H229 VanDerWaalsContact C-N 3.29Å; Q227-H229 PolarHBondContact O-N 2.98Å; H229-V231 VanDerWaalsContact C-N 3.34Å; H229-V231 PolarHBondContact O-N 3.01Å; H229-I232 PolarHBondContact O-N 2.94Å; H229-I232 VanDerWaalsContact O-N 3.15Å; H229-Q233 PolarHBondContact CE1-NE2 3.39Å; H229-Q233 VanDerWaalsContact CE1-NE2 3.29Å; H229-Q233 PolarHBondContact NE2-NE2 3.32Å; H229-Q233 PolarHBondContact O-N 3.1Å
230	L	95	Very high	93.4	Very high	22 Å²	22	18.8 Å²	18.8	12%	0.115	10%	0.097	C	C	.	.	H	α-helix	trans	-62.2	-40.2	176.8	-64.2	179.9	0	0	0	112.1	T226 Q227 I232 Q233 N234 T408 H411	T226-L230 HydrophobicContact CG2-CD1 4.48Å; T226-L230 VanDerWaalsContact O-CG 3.31Å; T226-L230 WeakPolarHBondContact O-CG 3.21Å; T226-L230 PolarHBondContact O-N 3.27Å; Q227-L230 PolarHBondContact O-N 3.01Å; L230-I232 VanDerWaalsContact C-N 3.31Å; L230-I232 PolarHBondContact O-N 3.09Å; L230-Q233 PolarHBondContact O-N 3.21Å; L230-N234 PolarHBondContact O-N 3.22Å; L230-N234 PolarHBondContact O-ND2 3.35Å; L230-N234 PolarHBondContact O-OD1 3.06Å; L230-T408 HydrophobicContact CD1-CG2 4.3Å; L230-H411 HydrophobicContact CB-CB 4.29Å; L230-H411 HydrophobicContact CD2-CB 4.19Å
231	V	95.1	Very high	93.5	Very high	24 Å²	24	18.9 Å²	18.9	15%	0.145	10%	0.097	C	C	.	.	H	α-helix	trans	-57.6	-44.6	173.6	172.6	0	0	0	0	111.2	V115 Q227 S228 H229 N234 L235 F242 A407	V115-V231 HydrophobicContact CG1-CB 4.25Å; V115-V231 HydrophobicContact CG1-CG1 4.02Å; V115-V231 HydrophobicContact CG2-CG1 3.79Å; Q227-V231 VanDerWaalsContact O-CG2 3.31Å; Q227-V231 WeakPolarHBondContact O-CG2 3.34Å; Q227-V231 PolarHBondContact O-N 3.29Å; S228-V231 PolarHBondContact O-N 2.88Å; H229-V231 VanDerWaalsContact C-N 3.34Å; H229-V231 PolarHBondContact O-N 3.01Å; V231-N234 PolarHBondContact O-N 3.42Å; V231-L235 WeakPolarHBondContact O-CB 3.27Å; V231-L235 PolarHBondContact O-N 2.9Å; V231-F242 HydrophobicContact CG1-CD2 3.54Å; V231-F242 HydrophobicContact CG1-CE2 3.48Å; V231-F242 VanDerWaalsContact CG1-CE2 3.48Å; V231-A407 HydrophobicContact CG2-CB 3.35Å
232	I	93.4	Very high	93.4	Very high	0 Å²	0	19.2 Å²	19.2	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-69.4	-39.3	-179.5	-74.7	164.1	0	0	0	111.4	M112 V115 L116 Y158 T161 S228 H229 L230 N234 L235 F236	M112-I232 HydrophobicContact CG-CD1 3.72Å; M112-I232 HydrophobicContact CG-CG1 4.01Å; M112-I232 HydrophobicContact CG-CG2 4.06Å; M112-I232 HydrophobicContact SD-CG2 4.45Å; V115-I232 HydrophobicContact CB-CD1 4.13Å; V115-I232 HydrophobicContact CB-CG1 4.14Å; V115-I232 HydrophobicContact CG1-CD1 3.82Å; V115-I232 HydrophobicContact CG1-CG1 3.88Å; L116-I232 HydrophobicContact CD2-CD1 4.32Å; L116-I232 HydrophobicContact CG-CD1 4.06Å; Y158-I232 HydrophobicContact CD1-CD1 4.36Å; Y158-I232 HydrophobicContact CE1-CD1 3.37Å; Y158-I232 HydrophobicContact CE1-CG1 4.5Å; T161-I232 HydrophobicContact CG2-CG2 4.34Å; S228-I232 WeakPolarHBondContact O-CG1 3.31Å; S228-I232 PolarHBondContact O-N 2.79Å; S228-I232 VanDerWaalsContact O-N 3.07Å; H229-I232 PolarHBondContact O-N 2.94Å; H229-I232 VanDerWaalsContact O-N 3.15Å; L230-I232 VanDerWaalsContact C-N 3.31Å; L230-I232 PolarHBondContact O-N 3.09Å; I232-N234 VanDerWaalsContact C-N 3.34Å; I232-N234 PolarHBondContact O-N 3.45Å; I232-L235 WeakPolarHBondContact O-CB 3.5Å; I232-L235 PolarHBondContact O-N 2.89Å; I232-F236 HydrophobicContact CG2-CD2 4.13Å; I232-F236 HydrophobicContact CG2-CE1 4.4Å; I232-F236 HydrophobicContact CG2-CE2 3.74Å; I232-F236 HydrophobicContact CG2-CZ 3.91Å; I232-F236 WeakPolarHBondContact O-CG 2.88Å; I232-F236 PolarHBondContact O-N 3.33Å
233	Q	91.3	Very high	93.5	Very high	33 Å²	33	14.4 Å²	14.4	15%	0.154	7%	0.073	C	C	.	.	H	α-helix	trans	-60.8	-44.1	172.9	-72.8	-173.8	-23.7	0	0	111.6	H229 L230 L235 F236 E237 H411	H229-Q233 PolarHBondContact CE1-NE2 3.39Å; H229-Q233 VanDerWaalsContact CE1-NE2 3.29Å; H229-Q233 PolarHBondContact NE2-NE2 3.32Å; H229-Q233 PolarHBondContact O-N 3.1Å; L230-Q233 PolarHBondContact O-N 3.21Å; Q233-L235 VanDerWaalsContact C-N 3.33Å; Q233-L235 PolarHBondContact O-N 3.46Å; Q233-F236 PolarHBondContact O-N 3.06Å; Q233-E237 PolarHBondContact O-N 2.94Å; Q233-H411 PolarHBondContact OE1-CE1 3.4Å; Q233-H411 PolarHBondContact OE1-ND1 3.16Å
234	N	93.4	Very high	93.7	Very high	5 Å²	5	11.6 Å²	11.6	3%	0.027	6%	0.059	C	C	.	.	H	α-helix	trans	-63.6	-40	176.5	-60.9	-20.7	0	0	0	111.5	L230 V231 I232 F236 E237 W241 A407 V410 H411 I414	L230-N234 PolarHBondContact O-N 3.22Å; L230-N234 PolarHBondContact O-ND2 3.35Å; L230-N234 PolarHBondContact O-OD1 3.06Å; V231-N234 PolarHBondContact O-N 3.42Å; I232-N234 VanDerWaalsContact C-N 3.34Å; I232-N234 PolarHBondContact O-N 3.45Å; N234-F236 VanDerWaalsContact C-N 3.31Å; N234-F236 PolarHBondContact O-N 3.5Å; N234-E237 PolarHBondContact O-N 3.49Å; N234-W241 WeakPolarHBondContact O-CB 3.3Å; N234-A407 PolarHBondContact ND2-O 3.23Å; N234-A407 VanDerWaalsContact ND2-O 3.12Å; N234-V410 HydrophobicContact CB-CG1 4.1Å; N234-V410 WeakPolarHBondContact ND2-CG1 3.46Å; N234-H411 PolarHBondContact ND2-N 3.26Å; N234-H411 WeakPolarHBondContact OD1-CA 3.21Å; N234-H411 VanDerWaalsContact OD1-CB 3.3Å; N234-H411 WeakPolarHBondContact OD1-CB 3.39Å; N234-H411 PolarHBondContact OD1-ND1 3.38Å; N234-I414 HydrophobicContact CB-CD1 4.28Å
235	L	93.1	Very high	93.8	Very high	0 Å²	0	11.8 Å²	11.8	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-59.7	-39.5	175.9	173.5	68	0	0	0	112.2	L111 M112 V231 I232 Q233 G238 M239 F242	L111-L235 HydrophobicContact CB-CD1 4.19Å; L111-L235 HydrophobicContact CB-CD2 3.78Å; L111-L235 HydrophobicContact CD1-CD1 3.88Å; M112-L235 HydrophobicContact CB-CD2 4.36Å; V231-L235 WeakPolarHBondContact O-CB 3.27Å; V231-L235 PolarHBondContact O-N 2.9Å; I232-L235 WeakPolarHBondContact O-CB 3.5Å; I232-L235 PolarHBondContact O-N 2.89Å; Q233-L235 VanDerWaalsContact C-N 3.33Å; Q233-L235 PolarHBondContact O-N 3.46Å; L235-G238 CarbonylContact O-C 3.45Å; L235-G238 VanDerWaalsContact O-C 3.26Å; L235-G238 PolarHBondContact O-N 3.29Å; L235-G238 VanDerWaalsContact O-N 3.16Å; L235-M239 HydrophobicContact CD1-CB 4.43Å; L235-M239 HydrophobicContact CD1-CG 3.77Å; L235-F242 HydrophobicContact CB-CB 4.24Å; L235-F242 HydrophobicContact CD1-CB 3.91Å; L235-F242 HydrophobicContact CD1-CD1 4.27Å; L235-F242 HydrophobicContact CD1-CG 4.02Å
236	F	89.4	Confident	93.8	Very high	4 Å²	4	13 Å²	13	2%	0.018	7%	0.066	C	C	.	.	H	α-helix	trans	-75.5	-21.9	-178.8	-70.2	-13.7	0	0	0	114.2	M112 T161 Y165 F166 I232 Q233 N234 G238 P307 V308	M112-F236 HydrophobicContact CB-CE1 4.49Å; M112-F236 HydrophobicContact CG-CZ 4.33Å; M112-F236 HydrophobicContact SD-CE1 4.43Å; M112-F236 HydrophobicContact SD-CE2 4.42Å; M112-F236 HydrophobicContact SD-CZ 3.61Å; T161-F236 HydrophobicContact CG2-CD2 3.92Å; T161-F236 HydrophobicContact CG2-CE2 3.62Å; Y165-F236 HydrophobicContact CD1-CB 4.11Å; Y165-F236 HydrophobicContact CD1-CD2 4.12Å; Y165-F236 HydrophobicContact CD1-CG 4.44Å; Y165-F236 AromaticContact CD2-CD2 3.78Å; Y165-F236 HydrophobicContact CD2-CD2 3.78Å; Y165-F236 HydrophobicContact CD2-CE2 4.4Å; Y165-F236 HydrophobicContact CE1-CB 3.62Å; Y165-F236 HydrophobicContact CE1-CD2 4.27Å; Y165-F236 HydrophobicContact CE1-CG 4.38Å; Y165-F236 HydrophobicContact CE2-CB 4.35Å; Y165-F236 AromaticContact CE2-CD2 3.93Å; Y165-F236 HydrophobicContact CE2-CD2 3.93Å; Y165-F236 AromaticContact CG-CD2 3.88Å; Y165-F236 HydrophobicContact CG-CD2 3.88Å; Y165-F236 HydrophobicContact CG-CE2 4.46Å; F166-F236 HydrophobicContact CE2-CE2 4.01Å; F166-F236 HydrophobicContact CE2-CZ 4.26Å; F166-F236 HydrophobicContact CZ-CE2 4.36Å; F166-F236 HydrophobicContact CZ-CZ 4.15Å; I232-F236 HydrophobicContact CG2-CD2 4.13Å; I232-F236 HydrophobicContact CG2-CE1 4.4Å; I232-F236 HydrophobicContact CG2-CE2 3.74Å; I232-F236 HydrophobicContact CG2-CZ 3.91Å; I232-F236 WeakPolarHBondContact O-CG 2.88Å; I232-F236 PolarHBondContact O-N 3.33Å; Q233-F236 PolarHBondContact O-N 3.06Å; N234-F236 VanDerWaalsContact C-N 3.31Å; N234-F236 PolarHBondContact O-N 3.5Å; F236-G238 PolarHBondContact O-N 3.34Å; F236-P307 WeakPolarHBondContact O-CA 3.44Å; F236-P307 WeakPolarHBondContact O-CB 3.46Å; F236-V308 HydrophobicContact CD1-CB 4.19Å; F236-V308 HydrophobicContact CD1-CG2 4.05Å; F236-V308 PolarHBondContact O-N 3.36Å
237	E	88	Confident	93.9	Very high	50 Å²	50	13 Å²	13	23%	0.234	7%	0.068	C	C	.	.	T	Hydrogen-bonded Turn	trans	-72	-12.5	168	-62.9	-64.2	119	0	0	112.9	Y165 Q233 N234 I414 R419	Y165-E237 PolarHBondContact OH-OE1 3.01Å; Q233-E237 PolarHBondContact O-N 2.94Å; N234-E237 PolarHBondContact O-N 3.49Å; E237-I414 HydrophobicContact CG-CG2 4.49Å; E237-R419 IonicContact OE1-CZ 3.55Å; E237-R419 IonicContact OE1-NE 3.64Å; E237-R419 IonicContact OE1-NH2 2.67Å; E237-R419 PolarHBondContact OE1-NH2 3.21Å; E237-R419 IonicContact OE2-CZ 3.65Å; E237-R419 IonicContact OE2-NE 2.98Å; E237-R419 PolarHBondContact OE2-NE 3.49Å; E237-R419 IonicContact OE2-NH2 3.53Å
238	G	90.5	Very high	94	Very high	0 Å²	0	11.7 Å²	11.7	0%	0	6%	0.062	C	C	.	.			trans	143.9	136.5	178.3	0	0	0	0	0	110.6	L235 F236 I240 W241 F304	L235-G238 CarbonylContact O-C 3.45Å; L235-G238 VanDerWaalsContact O-C 3.26Å; L235-G238 PolarHBondContact O-N 3.29Å; L235-G238 VanDerWaalsContact O-N 3.16Å; F236-G238 PolarHBondContact O-N 3.34Å; G238-I240 PolarHBondContact O-N 3.45Å; G238-W241 WeakPolarHBondContact O-CB 3.41Å; G238-W241 PolarHBondContact O-N 3.46Å; G238-F304 CarbonylContact C-O 3.58Å
239	M	93.6	Very high	94	Very high	1 Å²	1	11.6 Å²	11.6	1%	0.005	6%	0.061	C	C	.	.	H	α-helix	trans	-58	-25.2	-178.2	-73.4	-173.1	-78.8	0	0	113.3	S108 L111 L235 W241 F242 L243 Y303 F304	S108-M239 WeakPolarHBondContact OG-CG 3.42Å; L111-M239 HydrophobicContact CD1-CG 4.21Å; L111-M239 HydrophobicContact CD1-SD 3.76Å; L235-M239 HydrophobicContact CD1-CB 4.43Å; L235-M239 HydrophobicContact CD1-CG 3.77Å; M239-W241 VanDerWaalsContact C-N 3.27Å; M239-W241 PolarHBondContact O-N 3.18Å; M239-F242 WeakPolarHBondContact O-CB 3.32Å; M239-F242 PolarHBondContact O-N 3.11Å; M239-L243 HydrophobicContact CB-CD1 4.36Å; M239-L243 WeakPolarHBondContact O-CB 3.5Å; M239-L243 WeakPolarHBondContact O-CG 3.34Å; M239-L243 PolarHBondContact O-N 3.18Å; M239-Y303 HydrophobicContact CE-CD1 3.46Å; M239-Y303 VanDerWaalsContact CE-CD1 3.46Å; M239-Y303 HydrophobicContact CE-CD2 4.06Å; M239-Y303 HydrophobicContact CE-CE1 3.28Å; M239-Y303 HydrophobicContact CE-CE2 3.92Å; M239-Y303 HydrophobicContact CE-CG 3.86Å; M239-Y303 WeakPolarHBondContact CE-O 3.32Å; M239-Y303 HydrophobicContact SD-CE1 4.19Å; M239-F304 CarbonylContact C-O 3.57Å; M239-F304 HydrophobicContact CB-CD1 4.27Å; M239-F304 HydrophobicContact CE-CD1 4.26Å; M239-F304 PolarHBondContact N-O 3.23Å
240	I	95.3	Very high	94	Very high	0 Å²	0	14.9 Å²	14.9	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-61.4	-34.6	176.9	-160.6	169.7	0	0	0	112.5	G238 F242 V244 L298 F304 V305 F327 F352	G238-I240 PolarHBondContact O-N 3.45Å; I240-F242 PolarHBondContact O-N 3.18Å; I240-V244 HydrophobicContact CG1-CG2 3.81Å; I240-V244 WeakPolarHBondContact O-CB 3.43Å; I240-V244 PolarHBondContact O-N 2.93Å; I240-V244 VanDerWaalsContact O-N 3.11Å; I240-L298 HydrophobicContact CD1-CB 3.74Å; I240-L298 HydrophobicContact CG1-CB 3.98Å; I240-L298 HydrophobicContact CG1-CD1 4.29Å; I240-F304 HydrophobicContact CB-CB 4.47Å; I240-F304 WeakPolarHBondContact CB-O 3.35Å; I240-F304 PolarHBondContact N-O 2.99Å; I240-V305 HydrophobicContact CD1-CG2 4.33Å; I240-F327 HydrophobicContact CD1-CE1 4.06Å; I240-F327 HydrophobicContact CG2-CE1 3.8Å; I240-F327 HydrophobicContact CG2-CZ 3.82Å; I240-F352 HydrophobicContact CB-CZ 4.48Å; I240-F352 HydrophobicContact CD1-CD1 3.59Å; I240-F352 HydrophobicContact CD1-CE1 3.35Å; I240-F352 HydrophobicContact CD1-CG 4.39Å; I240-F352 HydrophobicContact CD1-CZ 3.94Å; I240-F352 HydrophobicContact CG1-CD1 4.27Å; I240-F352 HydrophobicContact CG1-CE1 3.52Å; I240-F352 HydrophobicContact CG1-CZ 3.7Å; I240-F352 HydrophobicContact CG2-CE2 4.32Å; I240-F352 HydrophobicContact CG2-CZ 4.19Å
241	W	95	Very high	94	Very high	7 Å²	7	14.7 Å²	14.7	3%	0.027	8%	0.078	C	C	.	.	H	α-helix	trans	-70.7	-16.3	175.5	-68.1	111.9	0	0	0	113.2	N234 G238 M239 P245 L326 F352 L359 V410 Y413 I414 I418	N234-W241 WeakPolarHBondContact O-CB 3.3Å; G238-W241 WeakPolarHBondContact O-CB 3.41Å; G238-W241 PolarHBondContact O-N 3.46Å; M239-W241 VanDerWaalsContact C-N 3.27Å; M239-W241 PolarHBondContact O-N 3.18Å; W241-P245 WeakPolarHBondContact O-CD 3.45Å; W241-P245 VanDerWaalsContact O-CG 3.28Å; W241-P245 WeakPolarHBondContact O-CG 3.48Å; W241-L326 HydrophobicContact CH2-CD2 4.24Å; W241-L326 HydrophobicContact CZ2-CD2 3.57Å; W241-F352 AromaticContact CD2-CE2 3.96Å; W241-F352 HydrophobicContact CD2-CE2 3.96Å; W241-F352 AromaticContact CE2-CE2 3.85Å; W241-F352 AromaticContact CE3-CE2 3.85Å; W241-F352 HydrophobicContact CE3-CE2 3.85Å; W241-F352 HydrophobicContact CE3-CZ 4.49Å; W241-F352 AromaticContact CH2-CD2 3.87Å; W241-F352 HydrophobicContact CH2-CD2 3.87Å; W241-F352 AromaticContact CH2-CE2 3.52Å; W241-F352 HydrophobicContact CH2-CE2 3.52Å; W241-F352 AromaticContact CZ2-CD2 3.89Å; W241-F352 HydrophobicContact CZ2-CD2 3.89Å; W241-F352 AromaticContact CZ2-CE2 3.65Å; W241-F352 HydrophobicContact CZ2-CE2 3.65Å; W241-F352 HydrophobicContact CZ3-CD2 4.43Å; W241-F352 AromaticContact CZ3-CE2 3.65Å; W241-F352 HydrophobicContact CZ3-CE2 3.65Å; W241-L359 HydrophobicContact CE3-CD1 4.22Å; W241-L359 HydrophobicContact CZ3-CD1 3.97Å; W241-V410 HydrophobicContact CE3-CG1 4.3Å; W241-Y413 HydrophobicContact CZ3-CD1 4.38Å; W241-I414 HydrophobicContact CB-CD1 3.88Å; W241-I414 HydrophobicContact CD2-CD1 3.53Å; W241-I414 HydrophobicContact CD2-CG1 3.74Å; W241-I414 HydrophobicContact CE3-CD1 3.61Å; W241-I414 HydrophobicContact CE3-CG1 3.52Å; W241-I414 HydrophobicContact CG-CD1 3.65Å; W241-I414 HydrophobicContact CG-CG1 4.38Å; W241-I414 HydrophobicContact CH2-CG1 4.16Å; W241-I414 HydrophobicContact CZ2-CG1 4.32Å; W241-I414 HydrophobicContact CZ3-CD1 4.34Å; W241-I414 HydrophobicContact CZ3-CG1 3.74Å; W241-I418 HydrophobicContact CH2-CB 4.5Å; W241-I418 HydrophobicContact CH2-CD1 3.76Å; W241-I418 HydrophobicContact CH2-CG1 3.55Å; W241-I418 HydrophobicContact CH2-CG2 4.37Å; W241-I418 HydrophobicContact CZ2-CB 4.43Å; W241-I418 HydrophobicContact CZ2-CD1 4.24Å; W241-I418 HydrophobicContact CZ2-CG1 3.94Å; W241-I418 HydrophobicContact CZ2-CG2 3.87Å; W241-I418 HydrophobicContact CZ3-CG1 4.43Å
242	F	95.3	Very high	94	Very high	12 Å²	12	13.7 Å²	13.7	5%	0.053	7%	0.072	C	C	.	.	H	α-helix	trans	-93.8	-49.7	172.2	171.1	-95.2	0	0	0	111.3	F100 L111 V115 V231 L235 M239 I240 I246	F100-F242 HydrophobicContact CE2-CE1 4.22Å; F100-F242 HydrophobicContact CZ-CE1 4.11Å; L111-F242 HydrophobicContact CD1-CE1 4.45Å; L111-F242 HydrophobicContact CD2-CE1 3.87Å; L111-F242 HydrophobicContact CD2-CZ 4.32Å; V115-F242 HydrophobicContact CG2-CE2 3.87Å; V115-F242 HydrophobicContact CG2-CZ 4.32Å; V231-F242 HydrophobicContact CG1-CD2 3.54Å; V231-F242 HydrophobicContact CG1-CE2 3.48Å; V231-F242 VanDerWaalsContact CG1-CE2 3.48Å; L235-F242 HydrophobicContact CB-CB 4.24Å; L235-F242 HydrophobicContact CD1-CB 3.91Å; L235-F242 HydrophobicContact CD1-CD1 4.27Å; L235-F242 HydrophobicContact CD1-CG 4.02Å; M239-F242 WeakPolarHBondContact O-CB 3.32Å; M239-F242 PolarHBondContact O-N 3.11Å; I240-F242 PolarHBondContact O-N 3.18Å; F242-I246 HydrophobicContact CD1-CD1 4.13Å; F242-I246 HydrophobicContact CD2-CD1 3.49Å; F242-I246 VanDerWaalsContact CD2-CD1 3.49Å; F242-I246 HydrophobicContact CE1-CD1 3.8Å; F242-I246 HydrophobicContact CE2-CD1 3.12Å; F242-I246 HydrophobicContact CG-CD1 3.98Å; F242-I246 HydrophobicContact CZ-CD1 3.29Å; F242-I246 WeakPolarHBondContact O-CB 3.2Å; F242-I246 WeakPolarHBondContact O-CG1 3.27Å; F242-I246 PolarHBondContact O-N 2.88Å
243	L	96.1	Very high	94	Very high	10 Å²	10	16.4 Å²	16.4	5%	0.052	9%	0.087	C	C	.	.	H	α-helix	trans	-71.2	-43.9	-170.5	-68.1	176.7	0	0	0	113.3	F100 I104 M239 S247 L298 F304	F100-L243 HydrophobicContact CE1-CD2 4.35Å; F100-L243 HydrophobicContact CZ-CD2 3.98Å; I104-L243 HydrophobicContact CD1-CD1 4.48Å; I104-L243 HydrophobicContact CD1-CD2 3.56Å; I104-L243 HydrophobicContact CG1-CD2 4.02Å; I104-L243 HydrophobicContact CG2-CD1 4.41Å; M239-L243 HydrophobicContact CB-CD1 4.36Å; M239-L243 WeakPolarHBondContact O-CB 3.5Å; M239-L243 WeakPolarHBondContact O-CG 3.34Å; M239-L243 PolarHBondContact O-N 3.18Å; L243-S247 WeakPolarHBondContact O-CB 3.4Å; L243-S247 PolarHBondContact O-N 3.38Å; L243-S247 PolarHBondContact O-OG 3.38Å; L243-L298 HydrophobicContact CB-CD1 4.23Å; L243-F304 HydrophobicContact CD1-CD1 3.73Å; L243-F304 HydrophobicContact CD1-CE1 3.87Å
244	V	96.6	Very high	94	Very high	0 Å²	0	19.4 Å²	19.4	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-66	-48.1	-177.2	171.3	0	0	0	0	111.6	I240 S248 L298 F352	I240-V244 HydrophobicContact CG1-CG2 3.81Å; I240-V244 WeakPolarHBondContact O-CB 3.43Å; I240-V244 PolarHBondContact O-N 2.93Å; I240-V244 VanDerWaalsContact O-N 3.11Å; V244-S248 VanDerWaalsContact O-CB 3.31Å; V244-S248 WeakPolarHBondContact O-CB 3.43Å; V244-S248 PolarHBondContact O-N 3.36Å; V244-S248 PolarHBondContact O-OG 3.48Å; V244-L298 HydrophobicContact CG2-CD1 3.67Å; V244-F352 HydrophobicContact CG2-CE1 4.11Å; V244-F352 HydrophobicContact CG2-CZ 4.46Å
245	P	96.3	Very high	94.1	Very high	4 Å²	4	20.1 Å²	20.1	3%	0.026	11%	0.108	C	C	.	.	H	α-helix	trans	-57.6	-51.3	174	-34.1	43.4	0	0	0	114.6	W241 S247 S248 V249 L359 M406 V410	W241-P245 WeakPolarHBondContact O-CD 3.45Å; W241-P245 VanDerWaalsContact O-CG 3.28Å; W241-P245 WeakPolarHBondContact O-CG 3.48Å; P245-S247 VanDerWaalsContact C-N 3.34Å; P245-S247 PolarHBondContact O-N 2.89Å; P245-S248 WeakPolarHBondContact O-CB 3.46Å; P245-S248 PolarHBondContact O-N 3.41Å; P245-S248 VanDerWaalsContact O-N 3.14Å; P245-V249 PolarHBondContact O-N 3.26Å; P245-L359 HydrophobicContact CG-CD1 4.14Å; P245-M406 HydrophobicContact CB-CE 3.52Å; P245-M406 HydrophobicContact CB-CG 3.79Å; P245-M406 HydrophobicContact CB-SD 4.48Å; P245-M406 HydrophobicContact CG-CE 4.04Å; P245-V410 HydrophobicContact CB-CG2 3.63Å; P245-V410 HydrophobicContact CG-CG1 4.32Å; P245-V410 HydrophobicContact CG-CG2 3.41Å; P245-V410 VanDerWaalsContact CG-CG2 3.41Å
246	I	94.7	Very high	94.1	Very high	24 Å²	24	20.8 Å²	20.8	12%	0.123	11%	0.113	C	C	.	.	H	α-helix	trans	-62.9	-44.6	-177.4	-73.2	172.8	0	0	0	110.5	F242 S248 V249 I250 Q403	F242-I246 HydrophobicContact CD1-CD1 4.13Å; F242-I246 HydrophobicContact CD2-CD1 3.49Å; F242-I246 VanDerWaalsContact CD2-CD1 3.49Å; F242-I246 HydrophobicContact CE1-CD1 3.8Å; F242-I246 HydrophobicContact CE2-CD1 3.12Å; F242-I246 HydrophobicContact CG-CD1 3.98Å; F242-I246 HydrophobicContact CZ-CD1 3.29Å; F242-I246 WeakPolarHBondContact O-CB 3.2Å; F242-I246 WeakPolarHBondContact O-CG1 3.27Å; F242-I246 PolarHBondContact O-N 2.88Å; I246-S248 VanDerWaalsContact C-N 3.28Å; I246-S248 PolarHBondContact O-N 3.33Å; I246-V249 PolarHBondContact O-N 3.16Å; I246-I250 HydrophobicContact CG2-CD1 3.84Å; I246-I250 WeakPolarHBondContact O-CG1 3.25Å; I246-I250 PolarHBondContact O-N 2.87Å; I246-Q403 PolarHBondContact O-NE2 2.89Å
247	S	95.3	Very high	94.1	Very high	32 Å²	32	28 Å²	28	22%	0.224	14%	0.141	C	C	.	.	H	α-helix	trans	-65.5	-33.5	177.6	-55.2	0	0	0	0	111.8	L243 P245 I250 C251	L243-S247 WeakPolarHBondContact O-CB 3.4Å; L243-S247 PolarHBondContact O-N 3.38Å; L243-S247 PolarHBondContact O-OG 3.38Å; P245-S247 VanDerWaalsContact C-N 3.34Å; P245-S247 PolarHBondContact O-N 2.89Å; S247-I250 PolarHBondContact O-N 3.23Å; S247-C251 WeakPolarHBondContact O-CB 3.43Å; S247-C251 PolarHBondContact O-N 3.2Å
248	S	96.8	Very high	94.3	Very high	0 Å²	0	29.3 Å²	29.3	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-64.4	-43.6	175.2	-65.2	0	0	0	0	111.8	V244 P245 I246 C251 N252 T287 S360	V244-S248 VanDerWaalsContact O-CB 3.31Å; V244-S248 WeakPolarHBondContact O-CB 3.43Å; V244-S248 PolarHBondContact O-N 3.36Å; V244-S248 PolarHBondContact O-OG 3.48Å; P245-S248 WeakPolarHBondContact O-CB 3.46Å; P245-S248 PolarHBondContact O-N 3.41Å; P245-S248 VanDerWaalsContact O-N 3.14Å; I246-S248 VanDerWaalsContact C-N 3.28Å; I246-S248 PolarHBondContact O-N 3.33Å; S248-C251 PolarHBondContact O-N 2.8Å; S248-N252 WeakPolarHBondContact O-CB 3.44Å; S248-N252 PolarHBondContact O-N 2.94Å; S248-T287 VanDerWaalsContact O-CG2 3.31Å; S248-T287 WeakPolarHBondContact O-CG2 3.43Å; S248-S360 PolarHBondContact OG-OG 2.88Å; S248-S360 VanDerWaalsContact OG-OG 3.13Å
249	V	95.6	Very high	94.5	Very high	4 Å²	4	32.8 Å²	32.8	2%	0.024	17%	0.165	C	C	.	.	H	α-helix	trans	-63.2	-45	175.3	174.3	0	0	0	0	110.9	P245 I246 C251 N252 D253 A363 C402 Q403 M406	P245-V249 PolarHBondContact O-N 3.26Å; I246-V249 PolarHBondContact O-N 3.16Å; V249-C251 PolarHBondContact O-N 3.13Å; V249-N252 WeakPolarHBondContact O-CB 3.39Å; V249-N252 PolarHBondContact O-N 3.46Å; V249-D253 PolarHBondContact O-N 3.43Å; V249-A363 HydrophobicContact CG2-CB 3.89Å; V249-C402 HydrophobicContact CG1-CB 3.71Å; V249-Q403 HydrophobicContact CG1-CG 4.5Å; V249-M406 HydrophobicContact CG2-CB 4.06Å; V249-M406 HydrophobicContact CG2-CG 3.96Å; V249-M406 HydrophobicContact CG2-SD 4.42Å
250	I	94	Very high	94.4	Very high	80 Å²	80	33.6 Å²	33.6	41%	0.41	17%	0.173	S	C	.	.	H	α-helix	trans	-61.4	-46.1	176.9	-65.9	166.3	0	0	0	110.8	I246 S247 N252 D253 I254	I246-I250 HydrophobicContact CG2-CD1 3.84Å; I246-I250 WeakPolarHBondContact O-CG1 3.25Å; I246-I250 PolarHBondContact O-N 2.87Å; S247-I250 PolarHBondContact O-N 3.23Å; I250-N252 VanDerWaalsContact C-N 3.31Å; I250-N252 PolarHBondContact O-N 3Å; I250-D253 PolarHBondContact O-N 2.9Å; I250-I254 HydrophobicContact CG2-CD1 3.81Å; I250-I254 WeakPolarHBondContact O-CG1 3.36Å; I250-I254 PolarHBondContact O-N 2.97Å; I250-I254 VanDerWaalsContact O-N 3.09Å
251	C	95.7	Very high	94.1	Very high	18 Å²	18	40.2 Å²	40.2	12%	0.122	20%	0.202	C	C	.	.	H	α-helix	trans	-60	-43	176.9	-178.9	0	0	0	0	111.1	S247 S248 V249 I254 T255 F290	S247-C251 WeakPolarHBondContact O-CB 3.43Å; S247-C251 PolarHBondContact O-N 3.2Å; S248-C251 PolarHBondContact O-N 2.8Å; V249-C251 PolarHBondContact O-N 3.13Å; C251-I254 PolarHBondContact O-N 3.31Å; C251-T255 WeakPolarHBondContact O-CB 3.5Å; C251-T255 VanDerWaalsContact O-CG2 3.32Å; C251-T255 WeakPolarHBondContact O-CG2 3.3Å; C251-T255 PolarHBondContact O-N 2.96Å; C251-T255 PolarHBondContact O-OG1 2.92Å; C251-F290 HydrophobicContact CB-CB 4.46Å; C251-F290 HydrophobicContact CB-CD1 3.71Å; C251-F290 HydrophobicContact CB-CD2 4.47Å; C251-F290 HydrophobicContact CB-CE1 4.06Å; C251-F290 HydrophobicContact CB-CG 3.94Å; C251-F290 VanDerWaalsContact SG-CB 3.56Å; C251-F290 VanDerWaalsContact SG-CG 3.55Å
252	N	95.8	Very high	94	Very high	4 Å²	4	46.5 Å²	46.5	2%	0.021	23%	0.23	C	C	.	.	H	α-helix	trans	-60	-47.3	177.1	-174.3	60.4	0	0	0	111.8	S248 V249 I250 I254 T255 A256 T287 S364 P368	S248-N252 WeakPolarHBondContact O-CB 3.44Å; S248-N252 PolarHBondContact O-N 2.94Å; V249-N252 WeakPolarHBondContact O-CB 3.39Å; V249-N252 PolarHBondContact O-N 3.46Å; I250-N252 VanDerWaalsContact C-N 3.31Å; I250-N252 PolarHBondContact O-N 3Å; N252-I254 PolarHBondContact O-N 3.03Å; N252-T255 PolarHBondContact O-N 3.5Å; N252-T255 PolarHBondContact O-OG1 3.18Å; N252-A256 WeakPolarHBondContact O-CB 3.47Å; N252-A256 PolarHBondContact O-N 2.93Å; N252-T287 WeakPolarHBondContact CA-OG1 3.47Å; N252-T287 HydrophobicContact CB-CG2 4.22Å; N252-T287 WeakPolarHBondContact CB-OG1 3.41Å; N252-T287 PolarHBondContact N-OG1 2.79Å; N252-T287 PolarHBondContact OD1-OG1 3.45Å; N252-S364 VanDerWaalsContact OD1-CB 3.31Å; N252-S364 WeakPolarHBondContact OD1-CB 3.41Å; N252-S364 PolarHBondContact OD1-OG 3.27Å; N252-P368 WeakPolarHBondContact ND2-CG 3.43Å
253	D	91.7	Very high	93.9	Very high	57 Å²	57	52 Å²	52	31%	0.305	25%	0.254	S	S	.	.	H	α-helix	trans	-63.8	-40.4	179.6	-90.7	-31	0	0	0	112.8	V249 I250 Y257 K275	V249-D253 PolarHBondContact O-N 3.43Å; I250-D253 PolarHBondContact O-N 2.9Å; D253-Y257 WeakPolarHBondContact O-CB 3.43Å; D253-Y257 PolarHBondContact O-N 3.46Å; D253-K275 IonicContact OD1-NZ 3.35Å; D253-K275 PolarHBondContact OD1-NZ 2.95Å
254	I	92	Very high	93.6	Very high	95 Å²	95	52.9 Å²	52.9	49%	0.487	27%	0.265	S	S	.	.	H	α-helix	trans	-66.3	-51.8	177.5	-66	168.2	0	0	0	110.3	I250 C251 N252 Y257 L258	I250-I254 HydrophobicContact CG2-CD1 3.81Å; I250-I254 WeakPolarHBondContact O-CG1 3.36Å; I250-I254 PolarHBondContact O-N 2.97Å; I250-I254 VanDerWaalsContact O-N 3.09Å; C251-I254 PolarHBondContact O-N 3.31Å; N252-I254 PolarHBondContact O-N 3.03Å; I254-Y257 WeakPolarHBondContact O-CB 3.41Å; I254-Y257 PolarHBondContact O-N 3.46Å; I254-L258 HydrophobicContact CG2-CD1 4.03Å; I254-L258 HydrophobicContact CG2-CG 4.48Å; I254-L258 WeakPolarHBondContact O-CG 3.48Å; I254-L258 PolarHBondContact O-N 2.98Å
255	T	94.6	Very high	93.3	Very high	21 Å²	21	63.6 Å²	63.6	13%	0.129	31%	0.306	C	S	.	.	H	α-helix	trans	-70.7	-39.4	-174.6	54.8	0	0	0	0	111.4	C251 N252 Y257 L258 F259 G283	C251-T255 WeakPolarHBondContact O-CB 3.5Å; C251-T255 VanDerWaalsContact O-CG2 3.32Å; C251-T255 WeakPolarHBondContact O-CG2 3.3Å; C251-T255 PolarHBondContact O-N 2.96Å; C251-T255 PolarHBondContact O-OG1 2.92Å; N252-T255 PolarHBondContact O-N 3.5Å; N252-T255 PolarHBondContact O-OG1 3.18Å; T255-Y257 VanDerWaalsContact C-N 3.26Å; T255-Y257 PolarHBondContact O-N 3.38Å; T255-L258 PolarHBondContact O-N 3.07Å; T255-L258 VanDerWaalsContact O-N 3.11Å; T255-F259 VanDerWaalsContact O-CD2 3.26Å; T255-F259 WeakPolarHBondContact O-CD2 3.38Å; T255-F259 PolarHBondContact O-N 3.27Å; T255-G283 WeakPolarHBondContact OG1-CA 3.27Å
256	A	93.4	Very high	93	Very high	14 Å²	14	66.5 Å²	66.5	12%	0.116	32%	0.324	C	S	.	.	H	α-helix	trans	-61.5	-35.8	173.5	0	0	0	0	0	112.3	N252 G260 G279	N252-A256 WeakPolarHBondContact O-CB 3.47Å; N252-A256 PolarHBondContact O-N 2.93Å; A256-G260 WeakPolarHBondContact O-CA 3.33Å; A256-G260 PolarHBondContact O-N 2.88Å; A256-G279 VanDerWaalsContact CA-O 3.26Å; A256-G279 WeakPolarHBondContact CA-O 3.32Å; A256-G279 WeakPolarHBondContact CB-O 3.48Å; A256-G279 WeakPolarHBondContact O-CA 3.17Å
257	Y	90.3	Very high	92.8	Very high	156 Å²	156	69.3 Å²	69.3	61%	0.612	34%	0.344	S	S	*	.	H	α-helix	trans	-66.2	-45.7	171.3	172.5	-97.2	0	0	0	112.1	D253 I254 T255 G260 F261	D253-Y257 WeakPolarHBondContact O-CB 3.43Å; D253-Y257 PolarHBondContact O-N 3.46Å; I254-Y257 WeakPolarHBondContact O-CB 3.41Å; I254-Y257 PolarHBondContact O-N 3.46Å; T255-Y257 VanDerWaalsContact C-N 3.26Å; T255-Y257 PolarHBondContact O-N 3.38Å; Y257-G260 PolarHBondContact O-N 3.41Å; Y257-F261 WeakPolarHBondContact O-CB 3.44Å; Y257-F261 PolarHBondContact O-N 3.24Å
258	L	92.4	Very high	92.4	Very high	77 Å²	77	69.6 Å²	69.6	40%	0.403	34%	0.342	S	S	.	.	H	α-helix	trans	-61.8	-51.7	179.6	-69.4	173	0	0	0	111.7	I254 T255 G260 F261 F262	I254-L258 HydrophobicContact CG2-CD1 4.03Å; I254-L258 HydrophobicContact CG2-CG 4.48Å; I254-L258 WeakPolarHBondContact O-CG 3.48Å; I254-L258 PolarHBondContact O-N 2.98Å; T255-L258 PolarHBondContact O-N 3.07Å; T255-L258 VanDerWaalsContact O-N 3.11Å; L258-G260 VanDerWaalsContact C-N 3.32Å; L258-G260 PolarHBondContact O-N 2.94Å; L258-F261 PolarHBondContact O-N 3.41Å; L258-F262 WeakPolarHBondContact O-CD2 3.36Å; L258-F262 PolarHBondContact O-N 2.98Å
259	F	94.1	Very high	91.8	Very high	73 Å²	73	72.7 Å²	72.7	32%	0.32	36%	0.358	S	S	.	.	H	α-helix	trans	-64.4	-37.9	177.2	-78	-78.4	0	0	0	111.9	T255 F261 F262 F263 G264 S286	T255-F259 VanDerWaalsContact O-CD2 3.26Å; T255-F259 WeakPolarHBondContact O-CD2 3.38Å; T255-F259 PolarHBondContact O-N 3.27Å; F259-F261 VanDerWaalsContact C-N 3.31Å; F259-F261 PolarHBondContact O-N 3.19Å; F259-F262 PolarHBondContact O-N 3.43Å; F259-F263 AromaticContact CD1-CD2 3.77Å; F259-F263 HydrophobicContact CD1-CD2 3.77Å; F259-F263 AromaticContact CD1-CE2 3.93Å; F259-F263 HydrophobicContact CD1-CE2 3.93Å; F259-F263 HydrophobicContact CE1-CD2 4.49Å; F259-F263 HydrophobicContact CE1-CE2 4.22Å; F259-F263 WeakPolarHBondContact O-CA 3.16Å; F259-F263 WeakPolarHBondContact O-CB 3.39Å; F259-F263 PolarHBondContact O-N 3.18Å; F259-G264 PolarHBondContact O-N 3.06Å; F259-S286 WeakPolarHBondContact CE2-OG 3.29Å
260	G	91.4	Very high	91.1	Very high	18 Å²	18	82.4 Å²	82.4	19%	0.186	40%	0.4	C	S	.	.	H	α-helix	trans	-64.2	-34.8	174.3	0	0	0	0	0	113.1	A256 Y257 L258 G264 T276	A256-G260 WeakPolarHBondContact O-CA 3.33Å; A256-G260 PolarHBondContact O-N 2.88Å; Y257-G260 PolarHBondContact O-N 3.41Å; L258-G260 VanDerWaalsContact C-N 3.32Å; L258-G260 PolarHBondContact O-N 2.94Å; G260-G264 WeakPolarHBondContact O-CA 3.42Å; G260-G264 PolarHBondContact O-N 2.81Å; G260-T276 WeakPolarHBondContact CA-OG1 3.49Å
261	F	89.5	Confident	90.4	Very high	139 Å²	139	82 Å²	82	61%	0.61	40%	0.398	S	S	*	.	H	α-helix	trans	-71.5	-43.8	177.2	179.6	-97.2	0	0	0	112.5	Y257 L258 F259	Y257-F261 WeakPolarHBondContact O-CB 3.44Å; Y257-F261 PolarHBondContact O-N 3.24Å; L258-F261 PolarHBondContact O-N 3.41Å; F259-F261 VanDerWaalsContact C-N 3.31Å; F259-F261 PolarHBondContact O-N 3.19Å
262	F	92.8	Very high	89.3	Confident	139 Å²	139	82.3 Å²	82.3	61%	0.61	40%	0.401	S	S	*	.	H	α-helix	trans	-82.9	-36.3	-176.8	-71.8	-67.5	0	0	0	114	L258 F259	L258-F262 WeakPolarHBondContact O-CD2 3.36Å; L258-F262 PolarHBondContact O-N 2.98Å; F259-F262 PolarHBondContact O-N 3.43Å
263	F	93.4	Very high	88.2	Confident	127 Å²	127	86.8 Å²	86.8	56%	0.557	43%	0.43	S	S	*	.	H	α-helix	trans	-121.6	-5.1	-170.9	-55.9	-78.3	0	0	0	113.7	F259 R265 E278	F259-F263 AromaticContact CD1-CD2 3.77Å; F259-F263 HydrophobicContact CD1-CD2 3.77Å; F259-F263 AromaticContact CD1-CE2 3.93Å; F259-F263 HydrophobicContact CD1-CE2 3.93Å; F259-F263 HydrophobicContact CE1-CD2 4.49Å; F259-F263 HydrophobicContact CE1-CE2 4.22Å; F259-F263 WeakPolarHBondContact O-CA 3.16Å; F259-F263 WeakPolarHBondContact O-CB 3.39Å; F259-F263 PolarHBondContact O-N 3.18Å; F263-R265 PolarHBondContact O-N 3.31Å; F263-E278 HydrophobicContact CB-CB 4.32Å; F263-E278 WeakPolarHBondContact O-CG 3.33Å
264	G	88.6	Confident	87.6	Confident	28 Å²	28	93.4 Å²	93.4	29%	0.289	46%	0.456	S	S	.	.			trans	-68	123.4	-174	0	0	0	0	0	113.1	F259 G260 E278	F259-G264 PolarHBondContact O-N 3.06Å; G260-G264 WeakPolarHBondContact O-CA 3.42Å; G260-G264 PolarHBondContact O-N 2.81Å; G264-E278 WeakPolarHBondContact CA-OE2 3.33Å
265	R	90.1	Very high	87.3	Confident	225 Å²	225	92.3 Å²	92.3	85%	0.849	45%	0.448	S	S	*	.			trans	-131	-33.5	175.1	-62.8	-178.7	-177	178.6	0.7	111.7	F263 E278	F263-R265 PolarHBondContact O-N 3.31Å; R265-E278 PolarHBondContact N-OE1 3.11Å; R265-E278 PolarHBondContact N-OE2 3.08Å
266	T	91.2	Very high	87.2	Confident	65 Å²	65	92.3 Å²	92.3	40%	0.399	45%	0.448	S	S	.	.	S	Bend	trans	-107.9	117.3	-172.8	53.1	0	0	0	0	111.4	T276 W277 E278	T266-T276 CarbonylContact O-C 3.5Å; T266-T276 WeakPolarHBondContact O-CA 3.46Å; T266-T276 VanDerWaalsContact O-CB 3.27Å; T266-T276 WeakPolarHBondContact O-CB 3.46Å; T266-W277 PolarHBondContact O-N 3.3Å; T266-E278 PolarHBondContact N-OE1 3.2Å; T266-E278 VanDerWaalsContact N-OE1 3.13Å; T266-E278 PolarHBondContact N-OE2 3.31Å; T266-E278 PolarHBondContact OG1-OE1 3.24Å; T266-E278 PolarHBondContact OG1-OE2 2.67Å
267	P	89.5	Confident	87.3	Confident	84 Å²	84	97.7 Å²	97.7	55%	0.545	47%	0.465	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-68	139	179.4	28.1	-33.6	0	0	0	110.9
268	L	87.1	Confident	87.5	Confident	38 Å²	38	92.7 Å²	92.7	20%	0.199	45%	0.447	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-78.5	-46.3	-177	-178	63.9	0	0	0	112	K275 W277 F280 F372	L268-K275 HydrophobicContact CB-CB 4.47Å; L268-K275 WeakPolarHBondContact CB-O 3.49Å; L268-K275 PolarHBondContact N-O 3.4Å; L268-W277 HydrophobicContact CD1-CD2 3.49Å; L268-W277 VanDerWaalsContact CD1-CD2 3.49Å; L268-W277 HydrophobicContact CD1-CE3 3.97Å; L268-W277 HydrophobicContact CD1-CG 3.87Å; L268-W277 HydrophobicContact CD1-CH2 4.17Å; L268-W277 HydrophobicContact CD1-CZ2 3.71Å; L268-W277 HydrophobicContact CD1-CZ3 4.29Å; L268-F280 HydrophobicContact CD2-CB 4.26Å; L268-F280 HydrophobicContact CD2-CD2 4.07Å; L268-F280 HydrophobicContact CD2-CG 4.25Å; L268-F372 HydrophobicContact CD2-CE2 4.17Å; L268-F372 HydrophobicContact CD2-CZ 3.74Å
269	I	84.9	Confident	87.5	Confident	65 Å²	65	89.1 Å²	89.1	33%	0.333	43%	0.429	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-144.4	142	-177.2	-162.7	169.9	0	0	0	111.3	L271 S272 F372	I269-L271 VanDerWaalsContact C-N 3.25Å; I269-L271 HydrophobicContact CD1-CB 4.5Å; I269-L271 HydrophobicContact CG1-CB 4.37Å; I269-L271 HydrophobicContact CG2-CB 4.45Å; I269-L271 PolarHBondContact O-N 2.7Å; I269-S272 CarbonylContact O-C 3.07Å; I269-S272 VanDerWaalsContact O-C 3.23Å; I269-S272 PolarHBondContact O-N 3.23Å; I269-S272 VanDerWaalsContact O-N 3.12Å; I269-F372 HydrophobicContact CG2-CD1 4.46Å; I269-F372 HydrophobicContact CG2-CE1 4.43Å
270	K	80.4	Confident	87.5	Confident	207 Å²	207	87.3 Å²	87.3	90%	0.9	42%	0.421	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61	-33.5	179.8	-69	-174.5	179	-179.7	0	113.1	S272	K270-S272 PolarHBondContact O-N 3.39Å
271	L	79	Confident	87.7	Confident	72 Å²	72	90.5 Å²	90.5	38%	0.377	43%	0.433	S	S	.	.	T	Hydrogen-bonded Turn	trans	-64.3	-26.4	178.6	-175.9	65.1	0	0	0	112.9	I269 R379	I269-L271 VanDerWaalsContact C-N 3.25Å; I269-L271 HydrophobicContact CD1-CB 4.5Å; I269-L271 HydrophobicContact CG1-CB 4.37Å; I269-L271 HydrophobicContact CG2-CB 4.45Å; I269-L271 PolarHBondContact O-N 2.7Å; L271-R379 HydrophobicContact CD1-CB 4.41Å; L271-R379 HydrophobicContact CD1-CG 3.94Å
272	S	73.9	Confident	88	Confident	25 Å²	25	84.4 Å²	84.4	18%	0.175	41%	0.409	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.2	78.1	-178.4	-167.5	0	0	0	0	110.5	I269 K270 K274 K275	I269-S272 CarbonylContact O-C 3.07Å; I269-S272 VanDerWaalsContact O-C 3.23Å; I269-S272 PolarHBondContact O-N 3.23Å; I269-S272 VanDerWaalsContact O-N 3.12Å; K270-S272 PolarHBondContact O-N 3.39Å; S272-K274 PolarHBondContact O-N 2.94Å; S272-K275 PolarHBondContact O-N 3.4Å; S272-K275 VanDerWaalsContact O-N 3.08Å
273	P	71.6	Confident	88.1	Confident	97 Å²	97	77.8 Å²	77.8	63%	0.63	38%	0.38	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-65.4	-13.4	-171.2	25	-34.5	0	0	0	114
274	K	79.4	Confident	88.3	Confident	197 Å²	197	74 Å²	74	86%	0.857	36%	0.364	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-84	-15	177.9	-66.5	-174.6	177.7	-176	0	113.9	S272	S272-K274 PolarHBondContact O-N 2.94Å
275	K	86.2	Confident	88.7	Confident	72 Å²	72	79 Å²	79	31%	0.313	38%	0.377	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-88.9	129.4	178	-68.2	-83.5	-171.3	171.6	0	107.9	D253 L268 S272 F372	D253-K275 IonicContact OD1-NZ 3.35Å; D253-K275 PolarHBondContact OD1-NZ 2.95Å; L268-K275 HydrophobicContact CB-CB 4.47Å; L268-K275 WeakPolarHBondContact CB-O 3.49Å; L268-K275 PolarHBondContact N-O 3.4Å; S272-K275 PolarHBondContact O-N 3.4Å; S272-K275 VanDerWaalsContact O-N 3.08Å; K275-F372 HydrophobicContact CG-CE1 4.18Å
276	T	93.2	Very high	89	Confident	20 Å²	20	69.7 Å²	69.7	12%	0.123	35%	0.347	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.3	155.6	-174.6	62.6	0	0	0	0	112.1	G260 T266 E278 G279 F280	G260-T276 WeakPolarHBondContact CA-OG1 3.49Å; T266-T276 CarbonylContact O-C 3.5Å; T266-T276 WeakPolarHBondContact O-CA 3.46Å; T266-T276 VanDerWaalsContact O-CB 3.27Å; T266-T276 WeakPolarHBondContact O-CB 3.46Å; T276-E278 VanDerWaalsContact C-N 3.34Å; T276-E278 WeakPolarHBondContact CB-OE2 3.44Å; T276-G279 PolarHBondContact O-N 3.1Å; T276-G279 PolarHBondContact OG1-N 3.28Å; T276-F280 PolarHBondContact O-N 2.9Å
277	W	93.8	Very high	89.3	Confident	128 Å²	128	66.6 Å²	66.6	49%	0.485	33%	0.328	S	S	.	.	H	α-helix	trans	-63.8	-39.6	175.3	-88.5	100.4	0	0	0	111.9	T266 L268 G279 F280 I281	T266-W277 PolarHBondContact O-N 3.3Å; L268-W277 HydrophobicContact CD1-CD2 3.49Å; L268-W277 VanDerWaalsContact CD1-CD2 3.49Å; L268-W277 HydrophobicContact CD1-CE3 3.97Å; L268-W277 HydrophobicContact CD1-CG 3.87Å; L268-W277 HydrophobicContact CD1-CH2 4.17Å; L268-W277 HydrophobicContact CD1-CZ2 3.71Å; L268-W277 HydrophobicContact CD1-CZ3 4.29Å; W277-G279 VanDerWaalsContact C-N 3.31Å; W277-G279 PolarHBondContact O-N 3.28Å; W277-F280 HydrophobicContact CE3-CD1 4.46Å; W277-F280 HydrophobicContact CZ3-CD1 4.41Å; W277-F280 WeakPolarHBondContact O-CB 3.3Å; W277-F280 PolarHBondContact O-N 3.34Å; W277-I281 HydrophobicContact CE3-CD1 4.5Å; W277-I281 WeakPolarHBondContact O-CG1 3.43Å; W277-I281 PolarHBondContact O-N 3.22Å
278	E	94.4	Very high	89.7	Confident	51 Å²	51	64 Å²	64	24%	0.238	31%	0.31	C	S	.	.	H	α-helix	trans	-65.1	-38.9	178.9	-54.5	85.8	175.6	0	0	111	F263 G264 R265 T266 T276 G282	F263-E278 HydrophobicContact CB-CB 4.32Å; F263-E278 WeakPolarHBondContact O-CG 3.33Å; G264-E278 WeakPolarHBondContact CA-OE2 3.33Å; R265-E278 PolarHBondContact N-OE1 3.11Å; R265-E278 PolarHBondContact N-OE2 3.08Å; T266-E278 PolarHBondContact N-OE1 3.2Å; T266-E278 VanDerWaalsContact N-OE1 3.13Å; T266-E278 PolarHBondContact N-OE2 3.31Å; T266-E278 PolarHBondContact OG1-OE1 3.24Å; T266-E278 PolarHBondContact OG1-OE2 2.67Å; T276-E278 VanDerWaalsContact C-N 3.34Å; T276-E278 WeakPolarHBondContact CB-OE2 3.44Å; E278-G282 PolarHBondContact O-N 2.89Å
279	G	94.1	Very high	90.2	Very high	1 Å²	1	66.3 Å²	66.3	1%	0.01	33%	0.326	C	S	.	.	H	α-helix	trans	-63	-44.5	172.2	0	0	0	0	0	112.1	A256 T276 W277 G282 G283	A256-G279 VanDerWaalsContact CA-O 3.26Å; A256-G279 WeakPolarHBondContact CA-O 3.32Å; A256-G279 WeakPolarHBondContact CB-O 3.48Å; A256-G279 WeakPolarHBondContact O-CA 3.17Å; T276-G279 PolarHBondContact O-N 3.1Å; T276-G279 PolarHBondContact OG1-N 3.28Å; W277-G279 VanDerWaalsContact C-N 3.31Å; W277-G279 PolarHBondContact O-N 3.28Å; G279-G282 PolarHBondContact O-N 3.3Å; G279-G283 PolarHBondContact O-N 3.31Å
280	F	93.9	Very high	90.8	Very high	35 Å²	35	66.9 Å²	66.9	15%	0.154	33%	0.326	C	S	.	.	H	α-helix	trans	-61.1	-46.3	178.6	-174.4	-102.5	0	0	0	112.5	L268 T276 W277 G283 F284 S364 L365 P368	L268-F280 HydrophobicContact CD2-CB 4.26Å; L268-F280 HydrophobicContact CD2-CD2 4.07Å; L268-F280 HydrophobicContact CD2-CG 4.25Å; T276-F280 PolarHBondContact O-N 2.9Å; W277-F280 HydrophobicContact CE3-CD1 4.46Å; W277-F280 HydrophobicContact CZ3-CD1 4.41Å; W277-F280 WeakPolarHBondContact O-CB 3.3Å; W277-F280 PolarHBondContact O-N 3.34Å; F280-G283 PolarHBondContact O-N 2.91Å; F280-F284 PolarHBondContact O-N 3.35Å; F280-S364 WeakPolarHBondContact CE2-O 3.4Å; F280-L365 HydrophobicContact CE1-CD2 3.82Å; F280-L365 HydrophobicContact CZ-CD2 3.86Å; F280-P368 HydrophobicContact CE2-CG 4.28Å
281	I	95.4	Very high	91.6	Very high	86 Å²	86	57 Å²	57	44%	0.441	28%	0.283	S	S	.	.	H	α-helix	trans	-67.9	-44	178.8	-63.7	166	0	0	0	111.2	W277 G283 F284 F285	W277-I281 HydrophobicContact CE3-CD1 4.5Å; W277-I281 WeakPolarHBondContact O-CG1 3.43Å; W277-I281 PolarHBondContact O-N 3.22Å; I281-G283 VanDerWaalsContact C-N 3.33Å; I281-G283 PolarHBondContact O-N 3.04Å; I281-F284 WeakPolarHBondContact O-CB 3.3Å; I281-F284 PolarHBondContact O-N 3.42Å; I281-F285 HydrophobicContact CG2-CD2 4.04Å; I281-F285 HydrophobicContact CG2-CE2 3.72Å; I281-F285 VanDerWaalsContact O-CD2 3.29Å; I281-F285 WeakPolarHBondContact O-CD2 3.45Å; I281-F285 PolarHBondContact O-N 3.32Å
282	G	94.6	Very high	92.5	Very high	11 Å²	11	56.7 Å²	56.7	11%	0.113	28%	0.279	C	S	.	.	H	α-helix	trans	-64.5	-37.7	177.3	0	0	0	0	0	112.8	E278 G279 S286	E278-G282 PolarHBondContact O-N 2.89Å; G279-G282 PolarHBondContact O-N 3.3Å; G282-S286 WeakPolarHBondContact O-CB 3.37Å; G282-S286 PolarHBondContact O-N 3.23Å; G282-S286 PolarHBondContact O-OG 2.93Å
283	G	95.7	Very high	93.6	Very high	0 Å²	0	60 Å²	60	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-59.1	-47.9	172	0	0	0	0	0	111.6	T255 G279 F280 I281 F285 S286 T287	T255-G283 WeakPolarHBondContact OG1-CA 3.27Å; G279-G283 PolarHBondContact O-N 3.31Å; F280-G283 PolarHBondContact O-N 2.91Å; I281-G283 VanDerWaalsContact C-N 3.33Å; I281-G283 PolarHBondContact O-N 3.04Å; G283-F285 PolarHBondContact O-N 3.48Å; G283-S286 PolarHBondContact O-N 3.23Å; G283-T287 WeakPolarHBondContact O-CB 3.4Å; G283-T287 PolarHBondContact O-N 3.37Å; G283-T287 PolarHBondContact O-OG1 3.11Å
284	F	96.8	Very high	94.8	Very high	47 Å²	47	56.1 Å²	56.1	21%	0.206	27%	0.27	C	S	.	.	H	α-helix	trans	-52.9	-56.9	178.4	173.3	-101.9	0	0	0	114	F280 I281 S286 T287 V288 T361 S364 L365	F280-F284 PolarHBondContact O-N 3.35Å; I281-F284 WeakPolarHBondContact O-CB 3.3Å; I281-F284 PolarHBondContact O-N 3.42Å; F284-S286 VanDerWaalsContact C-N 3.29Å; F284-S286 PolarHBondContact O-N 2.94Å; F284-T287 PolarHBondContact O-N 2.97Å; F284-V288 HydrophobicContact CD2-CG2 4.4Å; F284-V288 HydrophobicContact CE2-CG2 3.98Å; F284-V288 HydrophobicContact CZ-CG2 4.12Å; F284-V288 WeakPolarHBondContact O-CG2 3.44Å; F284-V288 PolarHBondContact O-N 2.84Å; F284-V288 VanDerWaalsContact O-N 3.08Å; F284-T361 HydrophobicContact CE2-CG2 3.98Å; F284-S364 WeakPolarHBondContact CA-OG 3.37Å; F284-S364 WeakPolarHBondContact CB-OG 3.32Å; F284-S364 PolarHBondContact N-OG 2.88Å; F284-L365 HydrophobicContact CD2-CD1 4.39Å; F284-L365 HydrophobicContact CD2-CD2 3.78Å; F284-L365 HydrophobicContact CD2-CG 3.84Å; F284-L365 HydrophobicContact CE2-CD1 4.07Å; F284-L365 HydrophobicContact CE2-CD2 4.27Å; F284-L365 HydrophobicContact CE2-CG 4.01Å; F284-L365 HydrophobicContact CG-CD2 4.33Å
285	F	96.8	Very high	95.6	Very high	132 Å²	132	46.8 Å²	46.8	58%	0.579	23%	0.229	S	C	*	.	H	α-helix	trans	-62.4	-40.1	-179.5	-71.7	-70.1	0	0	0	111.9	I281 G283 V288 V289	I281-F285 HydrophobicContact CG2-CD2 4.04Å; I281-F285 HydrophobicContact CG2-CE2 3.72Å; I281-F285 VanDerWaalsContact O-CD2 3.29Å; I281-F285 WeakPolarHBondContact O-CD2 3.45Å; I281-F285 PolarHBondContact O-N 3.32Å; G283-F285 PolarHBondContact O-N 3.48Å; F285-V288 PolarHBondContact O-N 2.79Å; F285-V289 WeakPolarHBondContact O-CG2 3.3Å; F285-V289 PolarHBondContact O-N 3.46Å; F285-V289 VanDerWaalsContact O-N 3.1Å
286	S	97	Very high	96	Very high	30 Å²	30	47.7 Å²	47.7	21%	0.21	23%	0.232	C	C	.	.	H	α-helix	trans	-66	-41.6	-179.8	-56.5	0	0	0	0	112.2	F259 G282 G283 F284 V289 F290	F259-S286 WeakPolarHBondContact CE2-OG 3.29Å; G282-S286 WeakPolarHBondContact O-CB 3.37Å; G282-S286 PolarHBondContact O-N 3.23Å; G282-S286 PolarHBondContact O-OG 2.93Å; G283-S286 PolarHBondContact O-N 3.23Å; F284-S286 VanDerWaalsContact C-N 3.29Å; F284-S286 PolarHBondContact O-N 2.94Å; S286-V289 PolarHBondContact O-N 3.47Å; S286-F290 VanDerWaalsContact O-CB 3.25Å; S286-F290 WeakPolarHBondContact O-CB 3.43Å; S286-F290 PolarHBondContact O-N 3.04Å
287	T	97.4	Very high	96.2	Very high	0 Å²	0	50.1 Å²	50.1	0%	0	25%	0.246	C	C	.	.	H	α-helix	trans	-67.5	-39.2	179	-60.7	0	0	0	0	112	S248 N252 G283 F284 F290 G291 S360	S248-T287 VanDerWaalsContact O-CG2 3.31Å; S248-T287 WeakPolarHBondContact O-CG2 3.43Å; N252-T287 WeakPolarHBondContact CA-OG1 3.47Å; N252-T287 HydrophobicContact CB-CG2 4.22Å; N252-T287 WeakPolarHBondContact CB-OG1 3.41Å; N252-T287 PolarHBondContact N-OG1 2.79Å; N252-T287 PolarHBondContact OD1-OG1 3.45Å; G283-T287 WeakPolarHBondContact O-CB 3.4Å; G283-T287 PolarHBondContact O-N 3.37Å; G283-T287 PolarHBondContact O-OG1 3.11Å; F284-T287 PolarHBondContact O-N 2.97Å; T287-F290 PolarHBondContact O-N 3.23Å; T287-G291 PolarHBondContact O-N 3.09Å; T287-S360 WeakPolarHBondContact O-CB 3.5Å; T287-S360 PolarHBondContact O-OG 2.87Å
288	V	98	Very high	96.3	Very high	29 Å²	29	45.5 Å²	45.5	18%	0.176	23%	0.231	C	C	.	.	H	α-helix	trans	-64.5	-46	175.5	172	0	0	0	0	111	F284 F285 G291 F292 I357	F284-V288 HydrophobicContact CD2-CG2 4.4Å; F284-V288 HydrophobicContact CE2-CG2 3.98Å; F284-V288 HydrophobicContact CZ-CG2 4.12Å; F284-V288 WeakPolarHBondContact O-CG2 3.44Å; F284-V288 PolarHBondContact O-N 2.84Å; F284-V288 VanDerWaalsContact O-N 3.08Å; F285-V288 PolarHBondContact O-N 2.79Å; V288-G291 PolarHBondContact O-N 2.94Å; V288-F292 WeakPolarHBondContact O-CB 3.13Å; V288-F292 PolarHBondContact O-N 3.43Å; V288-I357 HydrophobicContact CG1-CG2 4.21Å
289	V	97.6	Very high	96.2	Very high	88 Å²	88	43.4 Å²	43.4	53%	0.533	22%	0.222	S	C	.	.	H	α-helix	trans	-62	-45.5	176.3	172.1	0	0	0	0	110.8	F285 S286 F292 I293	F285-V289 WeakPolarHBondContact O-CG2 3.3Å; F285-V289 PolarHBondContact O-N 3.46Å; F285-V289 VanDerWaalsContact O-N 3.1Å; S286-V289 PolarHBondContact O-N 3.47Å; V289-F292 PolarHBondContact O-N 2.91Å; V289-I293 HydrophobicContact CG1-CD1 3.87Å; V289-I293 WeakPolarHBondContact O-CG1 3.32Å; V289-I293 PolarHBondContact O-N 3.11Å; V289-I293 VanDerWaalsContact O-N 3.11Å
290	F	98.1	Very high	96.2	Very high	76 Å²	76	48.4 Å²	48.4	33%	0.333	24%	0.243	S	C	.	.	H	α-helix	trans	-59.5	-48.9	176.9	172.2	-94.8	0	0	0	112	C251 S286 T287 F292 I293 A294	C251-F290 HydrophobicContact CB-CB 4.46Å; C251-F290 HydrophobicContact CB-CD1 3.71Å; C251-F290 HydrophobicContact CB-CD2 4.47Å; C251-F290 HydrophobicContact CB-CE1 4.06Å; C251-F290 HydrophobicContact CB-CG 3.94Å; C251-F290 VanDerWaalsContact SG-CB 3.56Å; C251-F290 VanDerWaalsContact SG-CG 3.55Å; S286-F290 VanDerWaalsContact O-CB 3.25Å; S286-F290 WeakPolarHBondContact O-CB 3.43Å; S286-F290 PolarHBondContact O-N 3.04Å; T287-F290 PolarHBondContact O-N 3.23Å; F290-F292 VanDerWaalsContact C-N 3.34Å; F290-F292 PolarHBondContact O-N 3.3Å; F290-I293 PolarHBondContact O-N 3.43Å; F290-A294 HydrophobicContact CE1-CB 4.25Å; F290-A294 HydrophobicContact CZ-CB 4.3Å; F290-A294 VanDerWaalsContact O-CB 3.27Å; F290-A294 WeakPolarHBondContact O-CB 3.24Å; F290-A294 PolarHBondContact O-N 2.95Å
291	G	97.2	Very high	96.1	Very high	0 Å²	0	53.1 Å²	53.1	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-60.5	-42.5	179.7	0	0	0	0	0	112.7	T287 V288 I293 A294 A295 S356 S360	T287-G291 PolarHBondContact O-N 3.09Å; V288-G291 PolarHBondContact O-N 2.94Å; G291-I293 PolarHBondContact O-N 3.24Å; G291-A294 PolarHBondContact O-N 3.18Å; G291-A295 WeakPolarHBondContact O-CB 3.37Å; G291-A295 PolarHBondContact O-N 3.2Å; G291-S356 PolarHBondContact O-OG 2.85Å; G291-S360 WeakPolarHBondContact CA-OG 3.44Å
292	F	96.8	Very high	95.9	Very high	65 Å²	65	54 Å²	54	29%	0.285	26%	0.263	S	S	.	.	H	α-helix	trans	-62	-41	177.3	-171.5	-94.8	0	0	0	112.6	V288 V289 F290 Y296 L349 Q353 I357	V288-F292 WeakPolarHBondContact O-CB 3.13Å; V288-F292 PolarHBondContact O-N 3.43Å; V289-F292 PolarHBondContact O-N 2.91Å; F290-F292 VanDerWaalsContact C-N 3.34Å; F290-F292 PolarHBondContact O-N 3.3Å; F292-Y296 PolarHBondContact O-N 3.24Å; F292-L349 HydrophobicContact CE1-CD2 4.38Å; F292-L349 HydrophobicContact CZ-CD1 4.43Å; F292-L349 HydrophobicContact CZ-CD2 3.7Å; F292-Q353 HydrophobicContact CD2-CB 3.97Å; F292-Q353 HydrophobicContact CE2-CB 3.78Å; F292-Q353 HydrophobicContact CZ-CB 4.41Å; F292-I357 HydrophobicContact CD2-CD1 3.99Å; F292-I357 HydrophobicContact CD2-CG1 4.04Å; F292-I357 HydrophobicContact CE2-CD1 4.27Å
293	I	97.1	Very high	95.8	Very high	96 Å²	96	57 Å²	57	49%	0.492	27%	0.272	S	S	.	.	H	α-helix	trans	-71.6	-46	176.5	-65.5	168.4	0	0	0	110.8	V289 F290 G291 A295 Y296 V297	V289-I293 HydrophobicContact CG1-CD1 3.87Å; V289-I293 WeakPolarHBondContact O-CG1 3.32Å; V289-I293 PolarHBondContact O-N 3.11Å; V289-I293 VanDerWaalsContact O-N 3.11Å; F290-I293 PolarHBondContact O-N 3.43Å; G291-I293 PolarHBondContact O-N 3.24Å; I293-A295 VanDerWaalsContact C-N 3.31Å; I293-A295 PolarHBondContact O-N 3.21Å; I293-Y296 WeakPolarHBondContact O-CB 3.26Å; I293-Y296 PolarHBondContact O-N 3.2Å; I293-V297 HydrophobicContact CG2-CG2 4.41Å; I293-V297 WeakPolarHBondContact O-CG2 3.48Å; I293-V297 PolarHBondContact O-N 3.08Å
294	A	96.9	Very high	95.7	Very high	15 Å²	15	58.8 Å²	58.8	12%	0.124	28%	0.279	C	S	.	.	H	α-helix	trans	-60.6	-42	179.8	0	0	0	0	0	111.5	F290 G291 V297 L298	F290-A294 HydrophobicContact CE1-CB 4.25Å; F290-A294 HydrophobicContact CZ-CB 4.3Å; F290-A294 VanDerWaalsContact O-CB 3.27Å; F290-A294 WeakPolarHBondContact O-CB 3.24Å; F290-A294 PolarHBondContact O-N 2.95Å; G291-A294 PolarHBondContact O-N 3.18Å; A294-V297 PolarHBondContact O-N 3.27Å; A294-L298 WeakPolarHBondContact O-CB 3.35Å; A294-L298 WeakPolarHBondContact O-CG 3.5Å; A294-L298 PolarHBondContact O-N 3.06Å
295	A	96.5	Very high	95.4	Very high	0 Å²	0	56.7 Å²	56.7	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-56.7	-50.3	172.9	0	0	0	0	0	111.4	G291 I293 V297 L298 S299 F352 Q353	G291-A295 WeakPolarHBondContact O-CB 3.37Å; G291-A295 PolarHBondContact O-N 3.2Å; I293-A295 VanDerWaalsContact C-N 3.31Å; I293-A295 PolarHBondContact O-N 3.21Å; A295-V297 PolarHBondContact O-N 2.9Å; A295-L298 PolarHBondContact O-N 3.03Å; A295-S299 VanDerWaalsContact O-CB 3.27Å; A295-S299 WeakPolarHBondContact O-CB 3.22Å; A295-S299 PolarHBondContact O-N 3.35Å; A295-S299 PolarHBondContact O-OG 3Å; A295-F352 HydrophobicContact CB-CD1 3.67Å; A295-F352 HydrophobicContact CB-CE1 3.81Å; A295-Q353 HydrophobicContact CB-CB 4.5Å; A295-Q353 HydrophobicContact CB-CG 3.97Å
296	Y	95.8	Very high	95	Very high	92 Å²	92	50.5 Å²	50.5	36%	0.361	24%	0.243	S	C	.	.	H	α-helix	trans	-59.4	-42.5	178	176.6	-102.6	0	0	0	113.3	F292 I293 K300 Y350	F292-Y296 PolarHBondContact O-N 3.24Å; I293-Y296 WeakPolarHBondContact O-CB 3.26Å; I293-Y296 PolarHBondContact O-N 3.2Å; Y296-K300 VanDerWaalsContact OH-CE 3.32Å; Y296-K300 WeakPolarHBondContact OH-CE 3.39Å; Y296-K300 PolarHBondContact OH-NZ 3.05Å; Y296-Y350 AromaticContact CD2-CD2 3.82Å; Y296-Y350 HydrophobicContact CD2-CD2 3.82Å; Y296-Y350 AromaticContact CD2-CE2 3.74Å; Y296-Y350 HydrophobicContact CD2-CE2 3.74Å; Y296-Y350 HydrophobicContact CE2-CD2 4.36Å; Y296-Y350 AromaticContact CE2-CE2 3.9Å; Y296-Y350 HydrophobicContact CE2-CE2 3.9Å
297	V	96.3	Very high	94.5	Very high	71 Å²	71	51.3 Å²	51.3	43%	0.43	25%	0.248	S	C	.	.	H	α-helix	trans	-69.1	-47.3	-178.4	173.1	0	0	0	0	111.1	I293 A294 A295 K300 Y301	I293-V297 HydrophobicContact CG2-CG2 4.41Å; I293-V297 WeakPolarHBondContact O-CG2 3.48Å; I293-V297 PolarHBondContact O-N 3.08Å; A294-V297 PolarHBondContact O-N 3.27Å; A295-V297 PolarHBondContact O-N 2.9Å; V297-K300 PolarHBondContact O-N 3.19Å; V297-Y301 WeakPolarHBondContact O-CD2 3.49Å
298	L	95.3	Very high	93.9	Very high	30 Å²	30	51.9 Å²	51.9	16%	0.157	25%	0.251	C	S	.	.	H	α-helix	trans	-72.6	-33.5	-176.1	-66.1	175.1	0	0	0	112.4	I240 L243 V244 A294 A295 K300 Y301 F304	I240-L298 HydrophobicContact CD1-CB 3.74Å; I240-L298 HydrophobicContact CG1-CB 3.98Å; I240-L298 HydrophobicContact CG1-CD1 4.29Å; L243-L298 HydrophobicContact CB-CD1 4.23Å; V244-L298 HydrophobicContact CG2-CD1 3.67Å; A294-L298 WeakPolarHBondContact O-CB 3.35Å; A294-L298 WeakPolarHBondContact O-CG 3.5Å; A294-L298 PolarHBondContact O-N 3.06Å; A295-L298 PolarHBondContact O-N 3.03Å; L298-K300 PolarHBondContact O-N 3.03Å; L298-K300 VanDerWaalsContact O-N 3.09Å; L298-Y301 PolarHBondContact O-N 2.92Å; L298-Y301 VanDerWaalsContact O-N 3.17Å; L298-F304 HydrophobicContact CB-CB 4.47Å; L298-F304 HydrophobicContact CB-CD2 4.38Å; L298-F304 HydrophobicContact CD2-CD1 4.42Å; L298-F304 HydrophobicContact CD2-CD2 3.56Å; L298-F304 HydrophobicContact CD2-CE2 3.7Å; L298-F304 HydrophobicContact CD2-CG 3.97Å; L298-F304 HydrophobicContact CD2-CZ 4.19Å
299	S	94.3	Very high	92.9	Very high	8 Å²	8	56 Å²	56	6%	0.056	27%	0.269	C	S	.	.	T	Hydrogen-bonded Turn	trans	-63.1	-14.4	177.8	-65.4	0	0	0	0	114.2	A295 Y301	A295-S299 VanDerWaalsContact O-CB 3.27Å; A295-S299 WeakPolarHBondContact O-CB 3.22Å; A295-S299 PolarHBondContact O-N 3.35Å; A295-S299 PolarHBondContact O-OG 3Å; S299-Y301 VanDerWaalsContact C-N 3.32Å
300	K	92.9	Very high	91.8	Very high	105 Å²	105	53 Å²	53	46%	0.457	25%	0.248	S	C	.	.	T	Hydrogen-bonded Turn	trans	-73.2	-22.7	176	-67.5	-179.1	-180	-171	0	113.9	Y296 V297 L298	Y296-K300 VanDerWaalsContact OH-CE 3.32Å; Y296-K300 WeakPolarHBondContact OH-CE 3.39Å; Y296-K300 PolarHBondContact OH-NZ 3.05Å; V297-K300 PolarHBondContact O-N 3.19Å; L298-K300 PolarHBondContact O-N 3.03Å; L298-K300 VanDerWaalsContact O-N 3.09Å
301	Y	93	Very high	90.5	Very high	135 Å²	135	54.4 Å²	54.4	53%	0.529	25%	0.251	S	S	.	.			trans	-111.4	119.8	-172.2	-57	-84.4	0	0	0	110.2	V297 L298 S299 Y303 F304	V297-Y301 WeakPolarHBondContact O-CD2 3.49Å; L298-Y301 PolarHBondContact O-N 2.92Å; L298-Y301 VanDerWaalsContact O-N 3.17Å; S299-Y301 VanDerWaalsContact C-N 3.32Å; Y301-Y303 PolarHBondContact O-N 3.11Å; Y301-F304 HydrophobicContact CD2-CD2 4.28Å; Y301-F304 HydrophobicContact CD2-CE2 4.24Å; Y301-F304 HydrophobicContact CG-CD2 4.39Å; Y301-F304 HydrophobicContact CG-CE2 4.39Å; Y301-F304 PolarHBondContact O-N 3.45Å; Y301-F304 VanDerWaalsContact O-N 3.09Å
302	Q	91.1	Very high	89.2	Confident	103 Å²	103	56.3 Å²	56.3	48%	0.481	27%	0.265	S	S	.	.	H	α-helix	trans	-54.6	-37.2	178.7	-67.4	-179.5	-28	0	0	112.2	F304 V305 C306 P323	Q302-F304 PolarHBondContact O-N 2.9Å; Q302-F304 VanDerWaalsContact O-N 3.14Å; Q302-V305 PolarHBondContact O-N 2.72Å; Q302-C306 WeakPolarHBondContact O-CB 3.46Å; Q302-C306 PolarHBondContact O-N 3.07Å; Q302-P323 HydrophobicContact CG-CG 3.96Å
303	Y	90.9	Very high	87.9	Confident	76 Å²	76	59.1 Å²	59.1	30%	0.298	28%	0.282	S	S	.	.	H	α-helix	trans	-48.5	-42.2	176.3	-175.2	-109.4	0	0	0	113.5	I104 Y105 G107 M239 Y301 T319	I104-Y303 PolarHBondContact O-OH 3.01Å; Y105-Y303 PolarHBondContact O-OH 3.45Å; Y105-Y303 VanDerWaalsContact O-OH 3.08Å; G107-Y303 WeakPolarHBondContact CA-OH 3.39Å; G107-Y303 PolarHBondContact N-OH 3.43Å; M239-Y303 HydrophobicContact CE-CD1 3.46Å; M239-Y303 VanDerWaalsContact CE-CD1 3.46Å; M239-Y303 HydrophobicContact CE-CD2 4.06Å; M239-Y303 HydrophobicContact CE-CE1 3.28Å; M239-Y303 HydrophobicContact CE-CE2 3.92Å; M239-Y303 HydrophobicContact CE-CG 3.86Å; M239-Y303 WeakPolarHBondContact CE-O 3.32Å; M239-Y303 HydrophobicContact SD-CE1 4.19Å; Y301-Y303 PolarHBondContact O-N 3.11Å; Y303-T319 WeakPolarHBondContact CD2-OG1 3.17Å
304	F	93.5	Very high	86.7	Confident	36 Å²	36	58.9 Å²	58.9	16%	0.158	29%	0.285	C	S	.	.	H	α-helix	trans	-84.4	-23.5	-179	-61.9	-58.6	0	0	0	113.6	I104 G238 M239 I240 L243 L298 Y301 Q302	I104-F304 HydrophobicContact CG2-CE1 3.84Å; G238-F304 CarbonylContact C-O 3.58Å; M239-F304 CarbonylContact C-O 3.57Å; M239-F304 HydrophobicContact CB-CD1 4.27Å; M239-F304 HydrophobicContact CE-CD1 4.26Å; M239-F304 PolarHBondContact N-O 3.23Å; I240-F304 HydrophobicContact CB-CB 4.47Å; I240-F304 WeakPolarHBondContact CB-O 3.35Å; I240-F304 PolarHBondContact N-O 2.99Å; L243-F304 HydrophobicContact CD1-CD1 3.73Å; L243-F304 HydrophobicContact CD1-CE1 3.87Å; L298-F304 HydrophobicContact CB-CB 4.47Å; L298-F304 HydrophobicContact CB-CD2 4.38Å; L298-F304 HydrophobicContact CD2-CD1 4.42Å; L298-F304 HydrophobicContact CD2-CD2 3.56Å; L298-F304 HydrophobicContact CD2-CE2 3.7Å; L298-F304 HydrophobicContact CD2-CG 3.97Å; L298-F304 HydrophobicContact CD2-CZ 4.19Å; Y301-F304 HydrophobicContact CD2-CD2 4.28Å; Y301-F304 HydrophobicContact CD2-CE2 4.24Å; Y301-F304 HydrophobicContact CG-CD2 4.39Å; Y301-F304 HydrophobicContact CG-CE2 4.39Å; Y301-F304 PolarHBondContact O-N 3.45Å; Y301-F304 VanDerWaalsContact O-N 3.09Å; Q302-F304 PolarHBondContact O-N 2.9Å; Q302-F304 VanDerWaalsContact O-N 3.14Å
305	V	91.9	Very high	85.5	Confident	4 Å²	4	63 Å²	63	2%	0.024	31%	0.305	C	S	.	.	H	α-helix	trans	-95.3	-38.2	-167.1	165	0	0	0	0	111.9	I240 Q302 P323 F327	I240-V305 HydrophobicContact CD1-CG2 4.33Å; Q302-V305 PolarHBondContact O-N 2.72Å; V305-P323 HydrophobicContact CG1-CB 4.39Å; V305-F327 HydrophobicContact CB-CD1 4.4Å; V305-F327 HydrophobicContact CB-CD2 4.42Å; V305-F327 HydrophobicContact CB-CG 4.25Å; V305-F327 HydrophobicContact CG1-CB 3.6Å; V305-F327 HydrophobicContact CG1-CD1 3.77Å; V305-F327 HydrophobicContact CG1-CD2 3.13Å; V305-F327 HydrophobicContact CG1-CE1 4.14Å; V305-F327 HydrophobicContact CG1-CE2 3.55Å; V305-F327 HydrophobicContact CG1-CG 3.21Å; V305-F327 HydrophobicContact CG1-CZ 4.02Å; V305-F327 HydrophobicContact CG2-CB 4.36Å; V305-F327 HydrophobicContact CG2-CD1 3.79Å; V305-F327 HydrophobicContact CG2-CE1 4.15Å; V305-F327 HydrophobicContact CG2-CG 4.04Å
306	C	88.4	Confident	84.2	Confident	1 Å²	1	65.9 Å²	65.9	1%	0.007	33%	0.325	C	S	.	.	S	Bend	trans	-71.8	139.9	-173.5	-74.7	0	0	0	0	111.9	Q302 T319 C321	Q302-C306 WeakPolarHBondContact O-CB 3.46Å; Q302-C306 PolarHBondContact O-N 3.07Å; C306-T319 WeakPolarHBondContact CB-O 3.41Å; C306-C321 WeakPolarHBondContact CA-SG 3.28Å; C306-C321 HydrophobicContact CB-CB 3.78Å; C306-C321 WeakPolarHBondContact CB-SG 3.35Å; C306-C321 VanDerWaalsContact SG-CA 3.53Å; C306-C321 WeakPolarHBondContact SG-CB 3.38Å; C306-C321 PolarHBondContact SG-N 2.82Å; C306-C321 PolarHBondContact SG-O 3.42Å; C306-C321 CovalentContact SG-SG 2.04Å; C306-C321 PolarHBondContact SG-SG 3.27Å
307	P	86.7	Confident	83	Confident	47 Å²	47	65 Å²	65	31%	0.305	32%	0.324	S	S	.	.	P	Polyproline II helix	trans	-65.4	156.9	173	29.6	-34.4	0	0	0	110.5	F236	F236-P307 WeakPolarHBondContact O-CA 3.44Å; F236-P307 WeakPolarHBondContact O-CB 3.46Å
308	V	83.9	Confident	82.1	Confident	12 Å²	12	62.8 Å²	62.8	7%	0.073	31%	0.31	C	S	.	.	P	Polyproline II helix	trans	-82.8	121.1	180	-179.3	0	0	0	0	109.2	S108 F236 F317 T319	S108-V308 VanDerWaalsContact CB-CG2 3.47Å; S108-V308 WeakPolarHBondContact OG-CG2 3.34Å; F236-V308 HydrophobicContact CD1-CB 4.19Å; F236-V308 HydrophobicContact CD1-CG2 4.05Å; F236-V308 PolarHBondContact O-N 3.36Å; V308-F317 HydrophobicContact CG1-CB 4.47Å; V308-F317 HydrophobicContact CG1-CD1 4.09Å; V308-T319 HydrophobicContact CG2-CG2 4.34Å
309	E	77.1	Confident	81.4	Confident	116 Å²	116	62.5 Å²	62.5	54%	0.542	31%	0.309	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.6	141.2	174.1	-67.4	-174.6	176.4	0	0	111	V318	E309-V318 PolarHBondContact N-O 3.11Å; E309-V318 PolarHBondContact O-N 2.56Å
310	Y	74.6	Confident	80.8	Confident	26 Å²	26	68.5 Å²	68.5	10%	0.102	34%	0.337	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-87.2	118.2	171.7	-177.6	-95.9	0	0	0	110	F169 N315 F317	F169-Y310 HydrophobicContact CB-CD1 3.86Å; F169-Y310 HydrophobicContact CB-CE1 3.69Å; F169-Y310 HydrophobicContact CB-CE2 4.44Å; F169-Y310 HydrophobicContact CB-CG 4.32Å; F169-Y310 AromaticContact CD2-CE1 3.94Å; F169-Y310 HydrophobicContact CD2-CE1 3.94Å; F169-Y310 HydrophobicContact CD2-CE2 4.05Å; F169-Y310 AromaticContact CD2-CZ 3.48Å; F169-Y310 VanDerWaalsContact CD2-CZ 3.48Å; F169-Y310 VanDerWaalsContact CD2-OH 3.26Å; F169-Y310 WeakPolarHBondContact CD2-OH 3.48Å; F169-Y310 HydrophobicContact CG-CE1 4.25Å; F169-Y310 HydrophobicContact CG-CE2 4.42Å; Y310-N315 VanDerWaalsContact OH-CA 3.32Å; Y310-N315 WeakPolarHBondContact OH-CA 3.06Å; Y310-N315 PolarHBondContact OH-OD1 3.38Å; Y310-F317 HydrophobicContact CD2-CD1 4.12Å; Y310-F317 AromaticContact CD2-CE1 3.61Å; Y310-F317 HydrophobicContact CD2-CE1 3.61Å; Y310-F317 HydrophobicContact CD2-CE2 4.47Å; Y310-F317 AromaticContact CD2-CZ 3.77Å; Y310-F317 HydrophobicContact CD2-CZ 3.77Å; Y310-F317 HydrophobicContact CE2-CZ 4.34Å; Y310-F317 HydrophobicContact CG-CE1 4.31Å
311	R	70.8	Confident	80.2	Confident	105 Å²	105	65.4 Å²	65.4	40%	0.396	33%	0.328	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-100	114.8	178	-78.1	-147.9	-173.1	-166.1	7.8	111	D313 V314 N315 S316 V318	R311-D313 VanDerWaalsContact C-N 3.28Å; R311-D313 VanDerWaalsContact CB-OD1 3.27Å; R311-D313 WeakPolarHBondContact CB-OD1 3.05Å; R311-D313 PolarHBondContact O-N 3.49Å; R311-V314 HydrophobicContact CB-CG2 3.84Å; R311-N315 PolarHBondContact O-N 3.3Å; R311-S316 PolarHBondContact N-O 2.95Å; R311-V318 HydrophobicContact CB-CG2 3.81Å; R311-V318 HydrophobicContact CG-CB 4.21Å; R311-V318 HydrophobicContact CG-CG2 3.86Å
312	S	69	Low	79.7	Confident	40 Å²	40	67.1 Å²	67.1	28%	0.28	34%	0.341	S	S	.	.	T	Hydrogen-bonded Turn	trans	-72.6	-13.1	-172.2	-60.2	0	0	0	0	115.5	R172 N315	R172-S312 PolarHBondContact NH1-O 2.82Å; R172-S312 PolarHBondContact NH2-O 3Å; S312-N315 PolarHBondContact O-OD1 2.93Å
313	D	71	Confident	79.4	Confident	123 Å²	123	63.7 Å²	63.7	66%	0.658	33%	0.327	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.2	-43.1	177.3	56.2	-33.2	0	0	0	111.9	R311	R311-D313 VanDerWaalsContact C-N 3.28Å; R311-D313 VanDerWaalsContact CB-OD1 3.27Å; R311-D313 WeakPolarHBondContact CB-OD1 3.05Å; R311-D313 PolarHBondContact O-N 3.49Å
314	V	71.4	Confident	79.1	Confident	91 Å²	91	63.1 Å²	63.1	55%	0.552	34%	0.335	S	S	*	.	T	Hydrogen-bonded Turn	trans	-97.1	-3.3	177.5	-96.1	0	0	0	0	113.8	R311 S316 V318	R311-V314 HydrophobicContact CB-CG2 3.84Å; V314-S316 PolarHBondContact O-N 2.91Å; V314-S316 VanDerWaalsContact O-N 3.16Å; V314-V318 HydrophobicContact CG2-CG2 4.15Å
315	N	70.9	Confident	78.8	Confident	102 Å²	102	68.2 Å²	68.2	55%	0.545	36%	0.359	S	S	.	.	T	Hydrogen-bonded Turn	trans	47	40	-174.5	-83.8	-10.3	0	0	0	112.8	R172 Y310 R311 S312	R172-N315 PolarHBondContact NH1-OD1 3.09Å; Y310-N315 VanDerWaalsContact OH-CA 3.32Å; Y310-N315 WeakPolarHBondContact OH-CA 3.06Å; Y310-N315 PolarHBondContact OH-OD1 3.38Å; R311-N315 PolarHBondContact O-N 3.3Å; S312-N315 PolarHBondContact O-OD1 2.93Å
316	S	69.7	Low	78.7	Confident	60 Å²	60	69.3 Å²	69.3	42%	0.42	36%	0.364	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-140.3	157.1	-175.1	-170.9	0	0	0	0	111.2	R311 V314	R311-S316 PolarHBondContact N-O 2.95Å; V314-S316 PolarHBondContact O-N 2.91Å; V314-S316 VanDerWaalsContact O-N 3.16Å
317	F	71.5	Confident	78.8	Confident	75 Å²	75	69.9 Å²	69.9	33%	0.329	37%	0.367	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-79.3	121.1	171.4	-63.1	-74.5	0	0	0	109	F109 F166 V308 Y310	F109-F317 HydrophobicContact CB-CD2 4.49Å; F109-F317 HydrophobicContact CD2-CE2 4.3Å; F166-F317 AromaticContact CD1-CE1 3.56Å; F166-F317 HydrophobicContact CD1-CE1 3.56Å; F166-F317 AromaticContact CD1-CZ 3.67Å; F166-F317 HydrophobicContact CD1-CZ 3.67Å; F166-F317 HydrophobicContact CE1-CD1 4.27Å; F166-F317 AromaticContact CE1-CE1 3.1Å; F166-F317 HydrophobicContact CE1-CE1 3.1Å; F166-F317 HydrophobicContact CE1-CE2 4.39Å; F166-F317 AromaticContact CE1-CZ 3.2Å; F166-F317 HydrophobicContact CE1-CZ 3.2Å; F166-F317 AromaticContact CZ-CE1 3.93Å; F166-F317 HydrophobicContact CZ-CE1 3.93Å; F166-F317 HydrophobicContact CZ-CZ 4.29Å; V308-F317 HydrophobicContact CG1-CB 4.47Å; V308-F317 HydrophobicContact CG1-CD1 4.09Å; Y310-F317 HydrophobicContact CD2-CD1 4.12Å; Y310-F317 AromaticContact CD2-CE1 3.61Å; Y310-F317 HydrophobicContact CD2-CE1 3.61Å; Y310-F317 HydrophobicContact CD2-CE2 4.47Å; Y310-F317 AromaticContact CD2-CZ 3.77Å; Y310-F317 HydrophobicContact CD2-CZ 3.77Å; Y310-F317 HydrophobicContact CE2-CZ 4.34Å; Y310-F317 HydrophobicContact CG-CE1 4.31Å
318	V	77.3	Confident	79	Confident	23 Å²	23	71.8 Å²	71.8	14%	0.139	37%	0.372	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.8	139.8	-177.7	-163.6	0	0	0	0	108.5	E309 R311 V314 E320	E309-V318 PolarHBondContact N-O 3.11Å; E309-V318 PolarHBondContact O-N 2.56Å; R311-V318 HydrophobicContact CB-CG2 3.81Å; R311-V318 HydrophobicContact CG-CB 4.21Å; R311-V318 HydrophobicContact CG-CG2 3.86Å; V314-V318 HydrophobicContact CG2-CG2 4.15Å; V318-E320 HydrophobicContact CG1-CB 3.74Å; V318-E320 HydrophobicContact CG1-CG 3.7Å
319	T	79.2	Confident	79.4	Confident	24 Å²	24	75.6 Å²	75.6	15%	0.147	39%	0.391	C	S	.	.			trans	-116.5	36.6	177.1	47.1	0	0	0	0	110.1	Y303 C306 V308	Y303-T319 WeakPolarHBondContact CD2-OG1 3.17Å; C306-T319 WeakPolarHBondContact CB-O 3.41Å; V308-T319 HydrophobicContact CG2-CG2 4.34Å
320	E	81.7	Confident	80.1	Confident	135 Å²	135	73.5 Å²	73.5	63%	0.631	38%	0.381	S	S	*	.			trans	-108.8	112.3	-179.1	-65.2	177.6	-173.9	0	0	109.1	V318	V318-E320 HydrophobicContact CG1-CB 3.74Å; V318-E320 HydrophobicContact CG1-CG 3.7Å
321	C	80.9	Confident	80.8	Confident	40 Å²	40	76.5 Å²	76.5	27%	0.27	40%	0.402	S	S	.	.			trans	-144.4	162.3	-179.9	80.1	0	0	0	0	109.7	C306 P323	C306-C321 WeakPolarHBondContact CA-SG 3.28Å; C306-C321 HydrophobicContact CB-CB 3.78Å; C306-C321 WeakPolarHBondContact CB-SG 3.35Å; C306-C321 VanDerWaalsContact SG-CA 3.53Å; C306-C321 WeakPolarHBondContact SG-CB 3.38Å; C306-C321 PolarHBondContact SG-N 2.82Å; C306-C321 PolarHBondContact SG-O 3.42Å; C306-C321 CovalentContact SG-SG 2.04Å; C306-C321 PolarHBondContact SG-SG 3.27Å; C321-P323 WeakPolarHBondContact O-CD 3.33Å
322	E	82.4	Confident	81.7	Confident	171 Å²	171	74.8 Å²	74.8	80%	0.799	40%	0.396	S	S	*	.	P	Polyproline II helix	trans	-74	119.1	161.8	-169	175.8	175.5	0	0	108.2	S324	E322-S324 PolarHBondContact O-N 3.18Å
323	P	85.1	Confident	82.6	Confident	30 Å²	30	77.6 Å²	77.6	20%	0.195	42%	0.416	C	S	.	.	P	Polyproline II helix	trans	-58.4	131.9	-177.7	-25.8	35.9	0	0	0	111.1	Q302 V305 C321 F327 Q328	Q302-P323 HydrophobicContact CG-CG 3.96Å; V305-P323 HydrophobicContact CG1-CB 4.39Å; C321-P323 WeakPolarHBondContact O-CD 3.33Å; P323-F327 HydrophobicContact CB-CB 4.2Å; P323-Q328 PolarHBondContact O-NE2 3.27Å
324	S	84.8	Confident	83.2	Confident	65 Å²	65	72.6 Å²	72.6	46%	0.455	39%	0.389	S	S	.	.	P	Polyproline II helix	trans	-62.2	163.1	176.9	69.9	0	0	0	0	111.6	E322 L326 F327 Q328	E322-S324 PolarHBondContact O-N 3.18Å; S324-L326 PolarHBondContact O-N 3.38Å; S324-F327 PolarHBondContact O-N 2.94Å; S324-F327 WeakPolarHBondContact OG-CD2 3.45Å; S324-Q328 PolarHBondContact O-N 2.84Å
325	E	87	Confident	83.8	Confident	142 Å²	142	71.6 Å²	71.6	66%	0.664	39%	0.385	S	S	*	.	G	3₁₀ helix	trans	-51.9	-27.5	179.2	-62.9	-175	169.1	0	0	113.2	F327 Q328 Q330 P351	E325-F327 PolarHBondContact O-N 3.25Å; E325-Q328 PolarHBondContact O-N 3.4Å; E325-Q330 PolarHBondContact O-NE2 3.21Å; E325-P351 WeakPolarHBondContact O-CG 3.26Å
326	L	88.3	Confident	84.3	Confident	27 Å²	27	72 Å²	72	14%	0.141	39%	0.393	C	S	.	.	G	3₁₀ helix	trans	-59.3	-28.5	176.7	-161.6	77.8	0	0	0	113.5	W241 S324 P351 F352 I418	W241-L326 HydrophobicContact CH2-CD2 4.24Å; W241-L326 HydrophobicContact CZ2-CD2 3.57Å; S324-L326 PolarHBondContact O-N 3.38Å; L326-P351 HydrophobicContact CD1-CB 4.14Å; L326-P351 VanDerWaalsContact O-CD 3.27Å; L326-P351 WeakPolarHBondContact O-CD 3.23Å; L326-F352 HydrophobicContact CD2-CB 4.48Å; L326-F352 HydrophobicContact CD2-CD2 3.94Å; L326-F352 HydrophobicContact CG-CB 4.2Å; L326-F352 PolarHBondContact O-N 3.29Å; L326-I418 HydrophobicContact CD1-CD1 4.13Å; L326-I418 HydrophobicContact CD2-CD1 4.38Å; L326-I418 HydrophobicContact CD2-CG2 4.08Å
327	F	91.9	Very high	85	Confident	14 Å²	14	76.7 Å²	76.7	6%	0.061	41%	0.406	C	S	.	.	G	3₁₀ helix	trans	-116.4	14.7	-175	-53.4	-74.7	0	0	0	112.2	I240 V305 P323 S324 E325 Y350 F352	I240-F327 HydrophobicContact CD1-CE1 4.06Å; I240-F327 HydrophobicContact CG2-CE1 3.8Å; I240-F327 HydrophobicContact CG2-CZ 3.82Å; V305-F327 HydrophobicContact CB-CD1 4.4Å; V305-F327 HydrophobicContact CB-CD2 4.42Å; V305-F327 HydrophobicContact CB-CG 4.25Å; V305-F327 HydrophobicContact CG1-CB 3.6Å; V305-F327 HydrophobicContact CG1-CD1 3.77Å; V305-F327 HydrophobicContact CG1-CD2 3.13Å; V305-F327 HydrophobicContact CG1-CE1 4.14Å; V305-F327 HydrophobicContact CG1-CE2 3.55Å; V305-F327 HydrophobicContact CG1-CG 3.21Å; V305-F327 HydrophobicContact CG1-CZ 4.02Å; V305-F327 HydrophobicContact CG2-CB 4.36Å; V305-F327 HydrophobicContact CG2-CD1 3.79Å; V305-F327 HydrophobicContact CG2-CE1 4.15Å; V305-F327 HydrophobicContact CG2-CG 4.04Å; P323-F327 HydrophobicContact CB-CB 4.2Å; S324-F327 PolarHBondContact O-N 2.94Å; S324-F327 WeakPolarHBondContact OG-CD2 3.45Å; E325-F327 PolarHBondContact O-N 3.25Å; F327-Y350 VanDerWaalsContact C-CD1 3.48Å; F327-Y350 VanDerWaalsContact O-CD1 3.24Å; F327-Y350 WeakPolarHBondContact O-CD1 3.3Å; F327-Y350 WeakPolarHBondContact O-CE1 3.41Å; F327-F352 HydrophobicContact CD1-CB 3.84Å; F327-F352 HydrophobicContact CD1-CD2 4.47Å; F327-F352 HydrophobicContact CD1-CG 4.1Å; F327-F352 HydrophobicContact CE1-CB 3.77Å; F327-F352 HydrophobicContact CE1-CD1 4.19Å; F327-F352 AromaticContact CE1-CD2 3.55Å; F327-F352 HydrophobicContact CE1-CD2 3.55Å; F327-F352 HydrophobicContact CE1-CE2 4.19Å; F327-F352 AromaticContact CE1-CG 3.55Å; F327-F352 HydrophobicContact CE1-CG 3.55Å; F327-F352 HydrophobicContact CZ-CD2 4.07Å; F327-F352 HydrophobicContact CZ-CG 4.49Å
328	Q	90.9	Very high	85.4	Confident	87 Å²	87	76.3 Å²	76.3	41%	0.407	41%	0.407	S	S	.	.	S	Bend	trans	-99.3	146.1	169	-64	-177.6	6.7	0	0	109.9	P323 S324 E325 Q330 P351	P323-Q328 PolarHBondContact O-NE2 3.27Å; S324-Q328 PolarHBondContact O-N 2.84Å; E325-Q328 PolarHBondContact O-N 3.4Å; Q328-Q330 PolarHBondContact O-N 3.48Å; Q328-P351 WeakPolarHBondContact O-CD 3.34Å
329	L	92.4	Very high	85.7	Confident	92 Å²	92	79.3 Å²	79.3	48%	0.482	42%	0.418	S	S	.	.			trans	-72.1	117.2	-176.5	-152	95.8	0	0	0	109.3	Y350	L329-Y350 HydrophobicContact CB-CE1 4.32Å; L329-Y350 HydrophobicContact CD1-CD1 4.36Å; L329-Y350 HydrophobicContact CD1-CD2 4.19Å; L329-Y350 HydrophobicContact CD1-CE1 3.97Å; L329-Y350 HydrophobicContact CD1-CE2 3.77Å; L329-Y350 HydrophobicContact CD1-CG 4.47Å
330	Q	90.5	Very high	85.8	Confident	71 Å²	71	82.1 Å²	82.1	33%	0.332	44%	0.444	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-111.1	148.5	178.1	-64.6	-171.8	7.9	0	0	110.7	E325 Q328 Y332 S348 L349 P351	E325-Q330 PolarHBondContact O-NE2 3.21Å; Q328-Q330 PolarHBondContact O-N 3.48Å; Q330-Y332 HydrophobicContact CB-CD2 4.5Å; Q330-Y332 HydrophobicContact CB-CE2 3.76Å; Q330-Y332 PolarHBondContact OE1-OH 3.19Å; Q330-Y332 VanDerWaalsContact OE1-OH 3.1Å; Q330-S348 WeakPolarHBondContact O-CA 3.42Å; Q330-L349 PolarHBondContact N-O 3.15Å; Q330-L349 PolarHBondContact O-N 3.29Å; Q330-P351 HydrophobicContact CB-CG 4.5Å; Q330-P351 HydrophobicContact CG-CG 4.01Å
331	T	90.9	Very high	86	Confident	89 Å²	89	80.3 Å²	80.3	55%	0.546	44%	0.442	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-97.8	118.2	179.2	-55.8	0	0	0	0	109.8	R346	T331-R346 HydrophobicContact CG2-CB 3.79Å; T331-R346 HydrophobicContact CG2-CG 4.28Å
332	Y	88	Confident	86	Confident	69 Å²	69	82.9 Å²	82.9	27%	0.271	45%	0.452	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-106.2	143.5	178.9	-63.9	-83.9	0	0	0	111.2	Q330 R346 V347 L349 P351 I354	Q330-Y332 HydrophobicContact CB-CD2 4.5Å; Q330-Y332 HydrophobicContact CB-CE2 3.76Å; Q330-Y332 PolarHBondContact OE1-OH 3.19Å; Q330-Y332 VanDerWaalsContact OE1-OH 3.1Å; Y332-R346 WeakPolarHBondContact O-CA 3.4Å; Y332-V347 PolarHBondContact N-O 3.05Å; Y332-V347 PolarHBondContact O-N 3.31Å; Y332-L349 HydrophobicContact CD2-CB 4.1Å; Y332-L349 HydrophobicContact CE2-CB 4.2Å; Y332-P351 WeakPolarHBondContact OH-CG 3.31Å; Y332-I354 HydrophobicContact CE1-CD1 4.24Å; Y332-I354 HydrophobicContact CE2-CD1 4.26Å
333	S	88.1	Confident	86	Confident	100 Å²	100	86.2 Å²	86.2	70%	0.699	46%	0.458	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-83.6	129.6	170.5	67.8	0	0	0	0	110
334	L	83.4	Confident	85.8	Confident	17 Å²	17	90.1 Å²	90.1	9%	0.089	47%	0.473	C	S	.	.	P	Polyproline II helix	trans	-74.3	140.7	-177.8	-75.6	173.8	0	0	0	111.1	L338 K339 L342 Q344 E345 V347	L334-L338 HydrophobicContact CB-CB 4.26Å; L334-L338 HydrophobicContact CD2-CB 4.06Å; L334-L338 HydrophobicContact CD2-CD1 4.01Å; L334-K339 HydrophobicContact CB-CG 3.87Å; L334-K339 WeakPolarHBondContact O-CE 3.42Å; L334-L342 HydrophobicContact CD1-CB 4.32Å; L334-L342 HydrophobicContact CD1-CD1 3.87Å; L334-L342 HydrophobicContact CD2-CD1 4.44Å; L334-Q344 VanDerWaalsContact CD1-O 3.27Å; L334-Q344 WeakPolarHBondContact CD1-O 3.37Å; L334-E345 PolarHBondContact N-O 3.23Å; L334-E345 VanDerWaalsContact N-O 3.12Å; L334-V347 HydrophobicContact CD1-CG1 3.69Å; L334-V347 HydrophobicContact CD2-CG1 4.08Å; L334-V347 HydrophobicContact CD2-CG2 3.65Å; L334-V347 HydrophobicContact CG-CG1 3.99Å; L334-V347 HydrophobicContact CG-CG2 4Å
335	P	85.1	Confident	85.6	Confident	70 Å²	70	93.2 Å²	93.2	46%	0.455	48%	0.48	S	S	.	.	P	Polyproline II helix	trans	-63.5	155.5	170.7	24.4	-31.6	0	0	0	111.2	F337 L338 K339	P335-F337 PolarHBondContact O-N 3.11Å; P335-F337 VanDerWaalsContact O-N 3.09Å; P335-L338 HydrophobicContact CG-CB 4.21Å; P335-L338 HydrophobicContact CG-CD1 3.76Å; P335-L338 HydrophobicContact CG-CG 4.09Å; P335-L338 PolarHBondContact O-N 3.37Å; P335-K339 PolarHBondContact O-N 2.89Å; P335-K339 VanDerWaalsContact O-N 3.09Å
336	P	81.8	Confident	85.7	Confident	110 Å²	110	94.5 Å²	94.5	71%	0.714	48%	0.479	S	S	*	.	H	α-helix	trans	-54.1	-38	-170.2	-25.7	33	0	0	0	114.3	K339 A340	P336-K339 PolarHBondContact O-N 3.5Å; P336-A340 PolarHBondContact O-N 3.22Å
337	F	83.3	Confident	85.7	Confident	160 Å²	160	94.5 Å²	94.5	70%	0.702	48%	0.48	S	S	*	.	H	α-helix	trans	-61.4	-45	176.5	174.6	-100.4	0	0	0	112.6	P335 A340 V341	P335-F337 PolarHBondContact O-N 3.11Å; P335-F337 VanDerWaalsContact O-N 3.09Å; F337-A340 PolarHBondContact O-N 3.47Å; F337-V341 HydrophobicContact CZ-CG2 4.47Å; F337-V341 PolarHBondContact O-N 3.5Å
338	L	81.1	Confident	85.7	Confident	66 Å²	66	96.9 Å²	96.9	35%	0.346	50%	0.499	S	S	.	.	H	α-helix	trans	-72.5	-29.9	179.6	-72.6	177.6	0	0	0	112.1	L334 P335 A340 V341 L342	L334-L338 HydrophobicContact CB-CB 4.26Å; L334-L338 HydrophobicContact CD2-CB 4.06Å; L334-L338 HydrophobicContact CD2-CD1 4.01Å; P335-L338 HydrophobicContact CG-CB 4.21Å; P335-L338 HydrophobicContact CG-CD1 3.76Å; P335-L338 HydrophobicContact CG-CG 4.09Å; P335-L338 PolarHBondContact O-N 3.37Å; L338-A340 VanDerWaalsContact C-N 3.31Å; L338-A340 PolarHBondContact O-N 3.23Å; L338-V341 PolarHBondContact O-N 3.41Å; L338-L342 HydrophobicContact CB-CD1 4.4Å; L338-L342 WeakPolarHBondContact O-CB 3.46Å; L338-L342 PolarHBondContact O-N 2.87Å
339	K	83.9	Confident	85.8	Confident	86 Å²	86	94.6 Å²	94.6	37%	0.374	49%	0.489	S	S	.	.	H	α-helix	trans	-60.4	-41.5	172.3	-65.2	-172.5	-176	-168.8	0	111.7	L334 P335 P336 V341 R343	L334-K339 HydrophobicContact CB-CG 3.87Å; L334-K339 WeakPolarHBondContact O-CE 3.42Å; P335-K339 PolarHBondContact O-N 2.89Å; P335-K339 VanDerWaalsContact O-N 3.09Å; P336-K339 PolarHBondContact O-N 3.5Å; K339-V341 VanDerWaalsContact C-N 3.29Å; K339-V341 PolarHBondContact O-N 2.92Å; K339-R343 WeakPolarHBondContact O-CA 3.42Å; K339-R343 PolarHBondContact O-N 3.34Å
340	A	80.2	Confident	85.8	Confident	83 Å²	83	91.7 Å²	91.7	69%	0.686	47%	0.472	S	S	*	.	H	α-helix	trans	-64.2	-34.6	178.6	0	0	0	0	0	112.5	P336 F337 L338	P336-A340 PolarHBondContact O-N 3.22Å; F337-A340 PolarHBondContact O-N 3.47Å; L338-A340 VanDerWaalsContact C-N 3.31Å; L338-A340 PolarHBondContact O-N 3.23Å
341	V	86.1	Confident	86	Confident	97 Å²	97	88.8 Å²	88.8	59%	0.588	46%	0.459	S	S	*	.	H	α-helix	trans	-82.2	-48.8	-179.4	178	0	0	0	0	112.2	F337 L338 K339	F337-V341 HydrophobicContact CZ-CG2 4.47Å; F337-V341 PolarHBondContact O-N 3.5Å; L338-V341 PolarHBondContact O-N 3.41Å; K339-V341 VanDerWaalsContact C-N 3.29Å; K339-V341 PolarHBondContact O-N 2.92Å
342	L	81.4	Confident	86.1	Confident	95 Å²	95	84.6 Å²	84.6	50%	0.497	43%	0.433	S	S	.	.	H	α-helix	trans	-89.1	-10.1	-171.1	-71.3	162.7	0	0	0	113.9	L334 L338 Q344	L334-L342 HydrophobicContact CD1-CB 4.32Å; L334-L342 HydrophobicContact CD1-CD1 3.87Å; L334-L342 HydrophobicContact CD2-CD1 4.44Å; L338-L342 HydrophobicContact CB-CD1 4.4Å; L338-L342 WeakPolarHBondContact O-CB 3.46Å; L338-L342 PolarHBondContact O-N 2.87Å; L342-Q344 PolarHBondContact O-N 3.47Å
343	R	81	Confident	86.5	Confident	241 Å²	241	81.5 Å²	81.5	91%	0.909	42%	0.421	S	S	*	.			trans	50.8	25.9	-175.1	-62.1	-173.7	176.7	-176.7	-0.6	114.1	K339	K339-R343 WeakPolarHBondContact O-CA 3.42Å; K339-R343 PolarHBondContact O-N 3.34Å
344	Q	80.7	Confident	86.7	Confident	112 Å²	112	80.6 Å²	80.6	52%	0.523	41%	0.408	S	S	.	.			trans	-129.7	143	-178.8	-164.5	171.2	-29.4	0	0	108.8	L334 L342 R346	L334-Q344 VanDerWaalsContact CD1-O 3.27Å; L334-Q344 WeakPolarHBondContact CD1-O 3.37Å; L342-Q344 PolarHBondContact O-N 3.47Å; Q344-R346 WeakPolarHBondContact CG-O 3.42Å; Q344-R346 PolarHBondContact NE2-O 2.96Å
345	E	81.8	Confident	87.3	Confident	129 Å²	129	81.6 Å²	81.6	60%	0.603	41%	0.412	S	S	*	.	S	Bend	trans	-90.8	-29.1	-177.2	-64.4	-163.9	148.3	0	0	113.5	L334	L334-E345 PolarHBondContact N-O 3.23Å; L334-E345 VanDerWaalsContact N-O 3.12Å
346	R	88.1	Confident	87.8	Confident	170 Å²	170	78.2 Å²	78.2	64%	0.642	39%	0.39	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-133.8	138.1	-173	-61.3	-176.4	-172.7	178	1.1	110.4	T331 Y332 Q344	T331-R346 HydrophobicContact CG2-CB 3.79Å; T331-R346 HydrophobicContact CG2-CG 4.28Å; Y332-R346 WeakPolarHBondContact O-CA 3.4Å; Q344-R346 WeakPolarHBondContact CG-O 3.42Å; Q344-R346 PolarHBondContact NE2-O 2.96Å
347	V	89.2	Confident	88.5	Confident	26 Å²	26	76.1 Å²	76.1	16%	0.158	37%	0.372	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-126.1	139.7	174.5	-69.3	0	0	0	0	109.8	Y332 L334 L349	Y332-V347 PolarHBondContact N-O 3.05Å; Y332-V347 PolarHBondContact O-N 3.31Å; L334-V347 HydrophobicContact CD1-CG1 3.69Å; L334-V347 HydrophobicContact CD2-CG1 4.08Å; L334-V347 HydrophobicContact CD2-CG2 3.65Å; L334-V347 HydrophobicContact CG-CG1 3.99Å; L334-V347 HydrophobicContact CG-CG2 4Å; V347-L349 HydrophobicContact CB-CG 4.46Å; V347-L349 HydrophobicContact CG2-CD1 3.81Å; V347-L349 HydrophobicContact CG2-CG 4.2Å
348	S	91	Very high	89.2	Confident	65 Å²	65	70 Å²	70	46%	0.455	35%	0.351	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.8	118.2	177	-49.9	0	0	0	0	109.3	Q330	Q330-S348 WeakPolarHBondContact O-CA 3.42Å
349	L	92.9	Very high	89.9	Confident	39 Å²	39	66.9 Å²	66.9	20%	0.204	34%	0.335	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.6	149.8	-174.4	-62.7	170.5	0	0	0	109.3	F292 Q330 Y332 V347	F292-L349 HydrophobicContact CE1-CD2 4.38Å; F292-L349 HydrophobicContact CZ-CD1 4.43Å; F292-L349 HydrophobicContact CZ-CD2 3.7Å; Q330-L349 PolarHBondContact N-O 3.15Å; Q330-L349 PolarHBondContact O-N 3.29Å; Y332-L349 HydrophobicContact CD2-CB 4.1Å; Y332-L349 HydrophobicContact CE2-CB 4.2Å; V347-L349 HydrophobicContact CB-CG 4.46Å; V347-L349 HydrophobicContact CG2-CD1 3.81Å; V347-L349 HydrophobicContact CG2-CG 4.2Å
350	Y	93.6	Very high	90.6	Very high	30 Å²	30	62.8 Å²	62.8	12%	0.118	32%	0.317	C	S	.	.			trans	-73.8	134.6	164.9	-64.2	-75.7	0	0	0	108.9	Y296 F327 L329 F352 Q353	Y296-Y350 AromaticContact CD2-CD2 3.82Å; Y296-Y350 HydrophobicContact CD2-CD2 3.82Å; Y296-Y350 AromaticContact CD2-CE2 3.74Å; Y296-Y350 HydrophobicContact CD2-CE2 3.74Å; Y296-Y350 HydrophobicContact CE2-CD2 4.36Å; Y296-Y350 AromaticContact CE2-CE2 3.9Å; Y296-Y350 HydrophobicContact CE2-CE2 3.9Å; F327-Y350 VanDerWaalsContact C-CD1 3.48Å; F327-Y350 VanDerWaalsContact O-CD1 3.24Å; F327-Y350 WeakPolarHBondContact O-CD1 3.3Å; F327-Y350 WeakPolarHBondContact O-CE1 3.41Å; L329-Y350 HydrophobicContact CB-CE1 4.32Å; L329-Y350 HydrophobicContact CD1-CD1 4.36Å; L329-Y350 HydrophobicContact CD1-CD2 4.19Å; L329-Y350 HydrophobicContact CD1-CE1 3.97Å; L329-Y350 HydrophobicContact CD1-CE2 3.77Å; L329-Y350 HydrophobicContact CD1-CG 4.47Å; Y350-F352 PolarHBondContact O-N 3.21Å; Y350-F352 VanDerWaalsContact O-N 3.14Å; Y350-Q353 VanDerWaalsContact O-CB 3.3Å; Y350-Q353 WeakPolarHBondContact O-CB 3.19Å; Y350-Q353 PolarHBondContact O-N 3.42Å
351	P	93.4	Very high	91.4	Very high	11 Å²	11	60.8 Å²	60.8	7%	0.071	30%	0.297	C	S	.	.	H	α-helix	trans	-51.6	-36.6	172.6	-25.4	30	0	0	0	112.5	E325 L326 Q328 Q330 Y332 Q353 I354 H355	E325-P351 WeakPolarHBondContact O-CG 3.26Å; L326-P351 HydrophobicContact CD1-CB 4.14Å; L326-P351 VanDerWaalsContact O-CD 3.27Å; L326-P351 WeakPolarHBondContact O-CD 3.23Å; Q328-P351 WeakPolarHBondContact O-CD 3.34Å; Q330-P351 HydrophobicContact CB-CG 4.5Å; Q330-P351 HydrophobicContact CG-CG 4.01Å; Y332-P351 WeakPolarHBondContact OH-CG 3.31Å; P351-Q353 PolarHBondContact O-N 2.93Å; P351-Q353 VanDerWaalsContact O-N 3.17Å; P351-I354 WeakPolarHBondContact O-CB 3.26Å; P351-I354 PolarHBondContact O-N 3.03Å; P351-H355 PolarHBondContact O-CD2 3.33Å; P351-H355 PolarHBondContact O-N 2.9Å
352	F	94.6	Very high	91.9	Very high	0 Å²	0	58.1 Å²	58.1	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-55.9	-30.1	174.5	-172.6	-101.6	0	0	0	114.1	I240 W241 V244 A295 L326 F327 Y350 I354 H355 S356	I240-F352 HydrophobicContact CB-CZ 4.48Å; I240-F352 HydrophobicContact CD1-CD1 3.59Å; I240-F352 HydrophobicContact CD1-CE1 3.35Å; I240-F352 HydrophobicContact CD1-CG 4.39Å; I240-F352 HydrophobicContact CD1-CZ 3.94Å; I240-F352 HydrophobicContact CG1-CD1 4.27Å; I240-F352 HydrophobicContact CG1-CE1 3.52Å; I240-F352 HydrophobicContact CG1-CZ 3.7Å; I240-F352 HydrophobicContact CG2-CE2 4.32Å; I240-F352 HydrophobicContact CG2-CZ 4.19Å; W241-F352 AromaticContact CD2-CE2 3.96Å; W241-F352 HydrophobicContact CD2-CE2 3.96Å; W241-F352 AromaticContact CE2-CE2 3.85Å; W241-F352 AromaticContact CE3-CE2 3.85Å; W241-F352 HydrophobicContact CE3-CE2 3.85Å; W241-F352 HydrophobicContact CE3-CZ 4.49Å; W241-F352 AromaticContact CH2-CD2 3.87Å; W241-F352 HydrophobicContact CH2-CD2 3.87Å; W241-F352 AromaticContact CH2-CE2 3.52Å; W241-F352 HydrophobicContact CH2-CE2 3.52Å; W241-F352 AromaticContact CZ2-CD2 3.89Å; W241-F352 HydrophobicContact CZ2-CD2 3.89Å; W241-F352 AromaticContact CZ2-CE2 3.65Å; W241-F352 HydrophobicContact CZ2-CE2 3.65Å; W241-F352 HydrophobicContact CZ3-CD2 4.43Å; W241-F352 AromaticContact CZ3-CE2 3.65Å; W241-F352 HydrophobicContact CZ3-CE2 3.65Å; V244-F352 HydrophobicContact CG2-CE1 4.11Å; V244-F352 HydrophobicContact CG2-CZ 4.46Å; A295-F352 HydrophobicContact CB-CD1 3.67Å; A295-F352 HydrophobicContact CB-CE1 3.81Å; L326-F352 HydrophobicContact CD2-CB 4.48Å; L326-F352 HydrophobicContact CD2-CD2 3.94Å; L326-F352 HydrophobicContact CG-CB 4.2Å; L326-F352 PolarHBondContact O-N 3.29Å; F327-F352 HydrophobicContact CD1-CB 3.84Å; F327-F352 HydrophobicContact CD1-CD2 4.47Å; F327-F352 HydrophobicContact CD1-CG 4.1Å; F327-F352 HydrophobicContact CE1-CB 3.77Å; F327-F352 HydrophobicContact CE1-CD1 4.19Å; F327-F352 AromaticContact CE1-CD2 3.55Å; F327-F352 HydrophobicContact CE1-CD2 3.55Å; F327-F352 HydrophobicContact CE1-CE2 4.19Å; F327-F352 AromaticContact CE1-CG 3.55Å; F327-F352 HydrophobicContact CE1-CG 3.55Å; F327-F352 HydrophobicContact CZ-CD2 4.07Å; F327-F352 HydrophobicContact CZ-CG 4.49Å; Y350-F352 PolarHBondContact O-N 3.21Å; Y350-F352 VanDerWaalsContact O-N 3.14Å; F352-I354 VanDerWaalsContact C-N 3.27Å; F352-I354 PolarHBondContact O-N 3.43Å; F352-H355 PolarHBondContact O-N 2.99Å; F352-S356 PolarHBondContact O-N 2.9Å
353	Q	95.2	Very high	92.7	Very high	4 Å²	4	53.6 Å²	53.6	2%	0.019	25%	0.253	C	S	.	.	H	α-helix	trans	-62.7	-35.7	174.9	-69.9	176.6	-102.1	0	0	111.9	F292 A295 Y350 P351 S356 I357	F292-Q353 HydrophobicContact CD2-CB 3.97Å; F292-Q353 HydrophobicContact CE2-CB 3.78Å; F292-Q353 HydrophobicContact CZ-CB 4.41Å; A295-Q353 HydrophobicContact CB-CB 4.5Å; A295-Q353 HydrophobicContact CB-CG 3.97Å; Y350-Q353 VanDerWaalsContact O-CB 3.3Å; Y350-Q353 WeakPolarHBondContact O-CB 3.19Å; Y350-Q353 PolarHBondContact O-N 3.42Å; P351-Q353 PolarHBondContact O-N 2.93Å; P351-Q353 VanDerWaalsContact O-N 3.17Å; Q353-S356 PolarHBondContact O-N 3.33Å; Q353-S356 PolarHBondContact O-OG 3.07Å; Q353-I357 PolarHBondContact O-N 3.33Å
354	I	93.3	Very high	93.4	Very high	81 Å²	81	42.1 Å²	42.1	42%	0.415	21%	0.21	S	C	.	.	H	α-helix	trans	-66.8	-44.8	176.7	-56.5	173.5	0	0	0	109.5	Y332 P351 F352 S356 I357	Y332-I354 HydrophobicContact CE1-CD1 4.24Å; Y332-I354 HydrophobicContact CE2-CD1 4.26Å; P351-I354 WeakPolarHBondContact O-CB 3.26Å; P351-I354 PolarHBondContact O-N 3.03Å; F352-I354 VanDerWaalsContact C-N 3.27Å; F352-I354 PolarHBondContact O-N 3.43Å; I354-S356 VanDerWaalsContact C-N 3.3Å; I354-S356 PolarHBondContact O-N 3Å; I354-I357 WeakPolarHBondContact O-CB 3.3Å; I354-I357 PolarHBondContact O-N 2.98Å
355	H	95.2	Very high	94	Very high	38 Å²	38	39.7 Å²	39.7	18%	0.176	20%	0.201	C	C	.	.	H	α-helix	trans	-62.9	-36.7	175.4	-64.4	-69	0	0	0	112.4	P351 F352 I357 A358 L359 Y413 I418	P351-H355 PolarHBondContact O-CD2 3.33Å; P351-H355 PolarHBondContact O-N 2.9Å; F352-H355 PolarHBondContact O-N 2.99Å; H355-I357 PolarHBondContact O-N 3.41Å; H355-A358 WeakPolarHBondContact O-CB 3.33Å; H355-A358 PolarHBondContact O-N 2.68Å; H355-L359 WeakPolarHBondContact O-CG 3.08Å; H355-L359 PolarHBondContact O-N 3.25Å; H355-L359 VanDerWaalsContact O-N 3.1Å; H355-Y413 HydrophobicContact CB-CE1 3.97Å; H355-Y413 AromaticContact ND1-CE1 3.54Å; H355-Y413 AromaticContact ND1-CZ 3.62Å; H355-Y413 PolarHBondContact ND1-OH 3.49Å; H355-I418 VanDerWaalsContact CE1-CD1 3.49Å; H355-I418 WeakPolarHBondContact CE1-CD1 3.43Å
356	S	96.6	Very high	94.6	Very high	0 Å²	0	37.2 Å²	37.2	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-59.9	-31.5	177.1	81.4	0	0	0	0	112.8	G291 F352 Q353 I354 A358 L359 S360	G291-S356 PolarHBondContact O-OG 2.85Å; F352-S356 PolarHBondContact O-N 2.9Å; Q353-S356 PolarHBondContact O-N 3.33Å; Q353-S356 PolarHBondContact O-OG 3.07Å; I354-S356 VanDerWaalsContact C-N 3.3Å; I354-S356 PolarHBondContact O-N 3Å; S356-A358 VanDerWaalsContact C-N 3.33Å; S356-A358 PolarHBondContact O-N 3.5Å; S356-L359 PolarHBondContact O-N 2.95Å; S356-S360 WeakPolarHBondContact O-CB 3.26Å; S356-S360 PolarHBondContact O-N 2.91Å; S356-S360 PolarHBondContact O-OG 2.76Å; S356-S360 VanDerWaalsContact O-OG 3.08Å
357	I	96.6	Very high	94.8	Very high	65 Å²	65	29.1 Å²	29.1	33%	0.333	16%	0.16	S	C	.	.	H	α-helix	trans	-62.2	-43	175.1	-63.5	168.5	0	0	0	110.3	V288 F292 Q353 I354 H355 T361	V288-I357 HydrophobicContact CG1-CG2 4.21Å; F292-I357 HydrophobicContact CD2-CD1 3.99Å; F292-I357 HydrophobicContact CD2-CG1 4.04Å; F292-I357 HydrophobicContact CE2-CD1 4.27Å; Q353-I357 PolarHBondContact O-N 3.33Å; I354-I357 WeakPolarHBondContact O-CB 3.3Å; I354-I357 PolarHBondContact O-N 2.98Å; H355-I357 PolarHBondContact O-N 3.41Å; I357-T361 WeakPolarHBondContact O-CB 3.26Å; I357-T361 PolarHBondContact O-N 3.2Å; I357-T361 PolarHBondContact O-OG1 3.35Å
358	A	96.7	Very high	94.9	Very high	32 Å²	32	28.3 Å²	28.3	26%	0.264	16%	0.156	S	C	.	.	H	α-helix	trans	-65.2	-43	176.6	0	0	0	0	0	111.5	H355 S356 T361 F362 Y413	H355-A358 WeakPolarHBondContact O-CB 3.33Å; H355-A358 PolarHBondContact O-N 2.68Å; S356-A358 VanDerWaalsContact C-N 3.33Å; S356-A358 PolarHBondContact O-N 3.5Å; A358-T361 PolarHBondContact O-N 3.05Å; A358-F362 PolarHBondContact O-N 2.9Å; A358-Y413 HydrophobicContact CB-CE2 3.71Å
359	L	97.3	Very high	94.9	Very high	0 Å²	0	30.6 Å²	30.6	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-60.5	-50.1	176.3	-60.5	178.8	0	0	0	111.8	W241 P245 H355 S356 T361 F362 A363 M406 F409 V410 Y413	W241-L359 HydrophobicContact CE3-CD1 4.22Å; W241-L359 HydrophobicContact CZ3-CD1 3.97Å; P245-L359 HydrophobicContact CG-CD1 4.14Å; H355-L359 WeakPolarHBondContact O-CG 3.08Å; H355-L359 PolarHBondContact O-N 3.25Å; H355-L359 VanDerWaalsContact O-N 3.1Å; S356-L359 PolarHBondContact O-N 2.95Å; L359-T361 PolarHBondContact O-N 3.34Å; L359-F362 PolarHBondContact O-N 3.5Å; L359-A363 WeakPolarHBondContact O-CB 3.25Å; L359-A363 PolarHBondContact O-N 3.49Å; L359-M406 HydrophobicContact CB-CE 3.95Å; L359-M406 HydrophobicContact CD2-CE 4.35Å; L359-M406 VanDerWaalsContact O-CE 3.29Å; L359-M406 WeakPolarHBondContact O-CE 3.5Å; L359-F409 HydrophobicContact CD2-CD1 4.26Å; L359-F409 HydrophobicContact CD2-CE1 3.87Å; L359-V410 HydrophobicContact CD2-CG2 4.16Å; L359-Y413 HydrophobicContact CD2-CD1 4.15Å; L359-Y413 HydrophobicContact CD2-CG 4.21Å
360	S	97.6	Very high	94.8	Very high	0 Å²	0	29 Å²	29	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-68.2	-34.6	-179.6	-63.6	0	0	0	0	112.8	S248 T287 G291 S356 A363 S364	S248-S360 PolarHBondContact OG-OG 2.88Å; S248-S360 VanDerWaalsContact OG-OG 3.13Å; T287-S360 WeakPolarHBondContact O-CB 3.5Å; T287-S360 PolarHBondContact O-OG 2.87Å; G291-S360 WeakPolarHBondContact CA-OG 3.44Å; S356-S360 WeakPolarHBondContact O-CB 3.26Å; S356-S360 PolarHBondContact O-N 2.91Å; S356-S360 PolarHBondContact O-OG 2.76Å; S356-S360 VanDerWaalsContact O-OG 3.08Å; S360-A363 PolarHBondContact O-N 3.09Å; S360-S364 PolarHBondContact O-N 2.92Å
361	T	97.4	Very high	94.5	Very high	42 Å²	42	28 Å²	28	26%	0.258	15%	0.15	S	C	.	.	H	α-helix	trans	-61	-48.5	172.9	-66.6	0	0	0	0	110.8	F284 I357 A358 L359 S364 L365	F284-T361 HydrophobicContact CE2-CG2 3.98Å; I357-T361 WeakPolarHBondContact O-CB 3.26Å; I357-T361 PolarHBondContact O-N 3.2Å; I357-T361 PolarHBondContact O-OG1 3.35Å; A358-T361 PolarHBondContact O-N 3.05Å; L359-T361 PolarHBondContact O-N 3.34Å; T361-S364 PolarHBondContact O-N 2.82Å; T361-L365 HydrophobicContact CG2-CD1 3.82Å; T361-L365 WeakPolarHBondContact O-CB 3.46Å; T361-L365 WeakPolarHBondContact O-CG 3.12Å; T361-L365 PolarHBondContact O-N 3.33Å
362	F	97.2	Very high	94.3	Very high	40 Å²	40	28.5 Å²	28.5	18%	0.175	15%	0.151	C	C	.	.	H	α-helix	trans	-63.8	-45.3	176.3	-175.8	-84.5	0	0	0	111.9	A358 L359 S364 L365 I366 G367 L405 M406 F409	A358-F362 PolarHBondContact O-N 2.9Å; L359-F362 PolarHBondContact O-N 3.5Å; F362-S364 PolarHBondContact O-N 3.43Å; F362-L365 PolarHBondContact O-N 3.5Å; F362-I366 HydrophobicContact CD1-CB 4.44Å; F362-I366 HydrophobicContact CD2-CB 3.93Å; F362-I366 HydrophobicContact CD2-CG1 4Å; F362-I366 HydrophobicContact CD2-CG2 4.39Å; F362-I366 HydrophobicContact CE1-CB 4.22Å; F362-I366 HydrophobicContact CE1-CG2 4.27Å; F362-I366 HydrophobicContact CE2-CB 3.69Å; F362-I366 HydrophobicContact CE2-CG1 4.01Å; F362-I366 HydrophobicContact CE2-CG2 3.64Å; F362-I366 HydrophobicContact CG-CB 4.3Å; F362-I366 HydrophobicContact CZ-CB 3.85Å; F362-I366 HydrophobicContact CZ-CG2 3.57Å; F362-I366 PolarHBondContact O-N 3.36Å; F362-G367 PolarHBondContact O-N 2.81Å; F362-L405 HydrophobicContact CE1-CB 4.5Å; F362-M406 HydrophobicContact CD1-SD 3.68Å; F362-M406 HydrophobicContact CE1-SD 4.3Å; F362-F409 HydrophobicContact CB-CD1 3.58Å; F362-F409 HydrophobicContact CB-CE1 3.33Å; F362-F409 HydrophobicContact CB-CE2 4.31Å; F362-F409 HydrophobicContact CB-CG 4.17Å; F362-F409 HydrophobicContact CB-CZ 3.73Å; F362-F409 HydrophobicContact CD1-CB 3.71Å; F362-F409 AromaticContact CD1-CD1 3.49Å; F362-F409 HydrophobicContact CD1-CD1 3.49Å; F362-F409 VanDerWaalsContact CD1-CD1 3.49Å; F362-F409 HydrophobicContact CD1-CD2 4.3Å; F362-F409 HydrophobicContact CD1-CE1 4.18Å; F362-F409 AromaticContact CD1-CG 3.55Å; F362-F409 HydrophobicContact CD1-CG 3.55Å; F362-F409 HydrophobicContact CD2-CB 4.25Å; F362-F409 AromaticContact CD2-CD1 3.91Å; F362-F409 HydrophobicContact CD2-CD1 3.91Å; F362-F409 AromaticContact CD2-CD2 3.43Å; F362-F409 HydrophobicContact CD2-CD2 3.43Å; F362-F409 VanDerWaalsContact CD2-CD2 3.43Å; F362-F409 HydrophobicContact CD2-CE1 4.08Å; F362-F409 AromaticContact CD2-CE2 3.64Å; F362-F409 HydrophobicContact CD2-CE2 3.64Å; F362-F409 AromaticContact CD2-CG 3.57Å; F362-F409 HydrophobicContact CD2-CG 3.57Å; F362-F409 AromaticContact CD2-CZ 3.96Å; F362-F409 HydrophobicContact CD2-CZ 3.96Å; F362-F409 HydrophobicContact CE1-CB 3.4Å; F362-F409 VanDerWaalsContact CE1-CB 3.4Å; F362-F409 HydrophobicContact CE1-CD1 4.13Å; F362-F409 HydrophobicContact CE1-CD2 4.42Å; F362-F409 AromaticContact CE1-CG 3.74Å; F362-F409 HydrophobicContact CE1-CG 3.74Å; F362-F409 HydrophobicContact CE2-CB 3.97Å; F362-F409 HydrophobicContact CE2-CD1 4.48Å; F362-F409 AromaticContact CE2-CD2 3.57Å; F362-F409 HydrophobicContact CE2-CD2 3.57Å; F362-F409 HydrophobicContact CE2-CE2 4.18Å; F362-F409 AromaticContact CE2-CG 3.74Å; F362-F409 HydrophobicContact CE2-CG 3.74Å; F362-F409 HydrophobicContact CG-CB 4.13Å; F362-F409 AromaticContact CG-CD1 3.36Å; F362-F409 HydrophobicContact CG-CD1 3.36Å; F362-F409 AromaticContact CG-CD2 3.82Å; F362-F409 HydrophobicContact CG-CD2 3.82Å; F362-F409 AromaticContact CG-CE1 3.61Å; F362-F409 HydrophobicContact CG-CE1 3.61Å; F362-F409 HydrophobicContact CG-CE2 4.05Å; F362-F409 AromaticContact CG-CG 3.47Å; F362-F409 HydrophobicContact CG-CG 3.47Å; F362-F409 VanDerWaalsContact CG-CG 3.47Å; F362-F409 AromaticContact CG-CZ 3.94Å; F362-F409 HydrophobicContact CG-CZ 3.94Å; F362-F409 HydrophobicContact CZ-CB 3.54Å; F362-F409 HydrophobicContact CZ-CD2 4.08Å; F362-F409 AromaticContact CZ-CG 3.82Å; F362-F409 HydrophobicContact CZ-CG 3.82Å
363	A	96.6	Very high	94.1	Very high	0 Å²	0	35.3 Å²	35.3	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-56.6	-34.7	179.7	0	0	0	0	0	112.6	V249 L359 S360 P368 M406	V249-A363 HydrophobicContact CG2-CB 3.89Å; L359-A363 WeakPolarHBondContact O-CB 3.25Å; L359-A363 PolarHBondContact O-N 3.49Å; S360-A363 PolarHBondContact O-N 3.09Å; A363-P368 WeakPolarHBondContact O-CD 3.22Å; A363-M406 HydrophobicContact CB-CE 4.1Å; A363-M406 HydrophobicContact CB-SD 3.83Å
364	S	95.9	Very high	93.7	Very high	0 Å²	0	35.3 Å²	35.3	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-88.2	-42.4	179.4	-176.8	0	0	0	0	113.9	N252 F280 F284 S360 T361 F362 P368	N252-S364 VanDerWaalsContact OD1-CB 3.31Å; N252-S364 WeakPolarHBondContact OD1-CB 3.41Å; N252-S364 PolarHBondContact OD1-OG 3.27Å; F280-S364 WeakPolarHBondContact CE2-O 3.4Å; F284-S364 WeakPolarHBondContact CA-OG 3.37Å; F284-S364 WeakPolarHBondContact CB-OG 3.32Å; F284-S364 PolarHBondContact N-OG 2.88Å; S360-S364 PolarHBondContact O-N 2.92Å; T361-S364 PolarHBondContact O-N 2.82Å; F362-S364 PolarHBondContact O-N 3.43Å; S364-P368 WeakPolarHBondContact O-CD 3.26Å; S364-P368 WeakPolarHBondContact O-CG 3.19Å
365	L	94.4	Very high	93.4	Very high	62 Å²	62	32.8 Å²	32.8	33%	0.325	17%	0.171	S	C	.	.	H	α-helix	trans	-80.7	-46.5	-175	-64.6	-179.6	0	0	0	112.6	F280 F284 T361 F362 F369	F280-L365 HydrophobicContact CE1-CD2 3.82Å; F280-L365 HydrophobicContact CZ-CD2 3.86Å; F284-L365 HydrophobicContact CD2-CD1 4.39Å; F284-L365 HydrophobicContact CD2-CD2 3.78Å; F284-L365 HydrophobicContact CD2-CG 3.84Å; F284-L365 HydrophobicContact CE2-CD1 4.07Å; F284-L365 HydrophobicContact CE2-CD2 4.27Å; F284-L365 HydrophobicContact CE2-CG 4.01Å; F284-L365 HydrophobicContact CG-CD2 4.33Å; T361-L365 HydrophobicContact CG2-CD1 3.82Å; T361-L365 WeakPolarHBondContact O-CB 3.46Å; T361-L365 WeakPolarHBondContact O-CG 3.12Å; T361-L365 PolarHBondContact O-N 3.33Å; F362-L365 PolarHBondContact O-N 3.5Å; L365-F369 WeakPolarHBondContact O-CD2 3.24Å; L365-F369 VanDerWaalsContact O-CE2 3.27Å; L365-F369 WeakPolarHBondContact O-CE2 3.23Å
366	I	94.3	Very high	93	Very high	77 Å²	77	32 Å²	32	40%	0.395	17%	0.174	S	C	.	.	T	Hydrogen-bonded Turn	trans	-103.8	-35.8	-170.8	-53.6	-64	0	0	0	111.2	F362 P368 F369	F362-I366 HydrophobicContact CD1-CB 4.44Å; F362-I366 HydrophobicContact CD2-CB 3.93Å; F362-I366 HydrophobicContact CD2-CG1 4Å; F362-I366 HydrophobicContact CD2-CG2 4.39Å; F362-I366 HydrophobicContact CE1-CB 4.22Å; F362-I366 HydrophobicContact CE1-CG2 4.27Å; F362-I366 HydrophobicContact CE2-CB 3.69Å; F362-I366 HydrophobicContact CE2-CG1 4.01Å; F362-I366 HydrophobicContact CE2-CG2 3.64Å; F362-I366 HydrophobicContact CG-CB 4.3Å; F362-I366 HydrophobicContact CZ-CB 3.85Å; F362-I366 HydrophobicContact CZ-CG2 3.57Å; F362-I366 PolarHBondContact O-N 3.36Å; I366-P368 VanDerWaalsContact C-CD 3.47Å; I366-P368 VanDerWaalsContact C-N 3.34Å; I366-F369 WeakPolarHBondContact O-CB 3.3Å; I366-F369 PolarHBondContact O-N 2.92Å
367	G	92.5	Very high	92.6	Very high	0 Å²	0	34.3 Å²	34.3	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-45.9	-47.7	176.7	0	0	0	0	0	114.6	F362 F369 G370	F362-G367 PolarHBondContact O-N 2.81Å; G367-F369 PolarHBondContact O-N 3.4Å; G367-F369 VanDerWaalsContact O-N 3.12Å; G367-G370 PolarHBondContact O-N 3.09Å
368	P	91.5	Very high	92.1	Very high	9 Å²	9	32.1 Å²	32.1	6%	0.058	17%	0.171	C	C	.	.	H	α-helix	trans	-62.3	-20.9	-178.8	-27.6	38.7	0	0	0	115.2	N252 F280 A363 S364 I366 G370 G371 F372	N252-P368 WeakPolarHBondContact ND2-CG 3.43Å; F280-P368 HydrophobicContact CE2-CG 4.28Å; A363-P368 WeakPolarHBondContact O-CD 3.22Å; S364-P368 WeakPolarHBondContact O-CD 3.26Å; S364-P368 WeakPolarHBondContact O-CG 3.19Å; I366-P368 VanDerWaalsContact C-CD 3.47Å; I366-P368 VanDerWaalsContact C-N 3.34Å; P368-G370 PolarHBondContact O-N 3.08Å; P368-G371 PolarHBondContact O-N 2.87Å; P368-G371 VanDerWaalsContact O-N 3.12Å; P368-F372 HydrophobicContact CB-CE2 4.21Å; P368-F372 HydrophobicContact CB-CZ 4.19Å; P368-F372 WeakPolarHBondContact O-CG 3.25Å; P368-F372 PolarHBondContact O-N 3.44Å
369	F	90.1	Very high	91.6	Very high	112 Å²	112	37.5 Å²	37.5	49%	0.491	19%	0.185	S	C	.	.	H	α-helix	trans	-65	-26.8	175.7	-74.6	-93.6	0	0	0	112.2	L365 I366 G367 F372 F373	L365-F369 WeakPolarHBondContact O-CD2 3.24Å; L365-F369 VanDerWaalsContact O-CE2 3.27Å; L365-F369 WeakPolarHBondContact O-CE2 3.23Å; I366-F369 WeakPolarHBondContact O-CB 3.3Å; I366-F369 PolarHBondContact O-N 2.92Å; G367-F369 PolarHBondContact O-N 3.4Å; G367-F369 VanDerWaalsContact O-N 3.12Å; F369-F372 HydrophobicContact CD1-CD2 4.05Å; F369-F372 HydrophobicContact CE1-CD2 4.46Å; F369-F372 HydrophobicContact CG-CD2 4.22Å; F369-F372 PolarHBondContact O-N 2.9Å; F369-F373 WeakPolarHBondContact O-CB 3.28Å; F369-F373 PolarHBondContact O-N 3.43Å
370	G	89.9	Confident	91	Very high	7 Å²	7	40.4 Å²	40.4	7%	0.072	21%	0.209	C	C	.	.	H	α-helix	trans	-61	-45	170.4	0	0	0	0	0	111.7	G367 P368 F373 A374	G367-G370 PolarHBondContact O-N 3.09Å; P368-G370 PolarHBondContact O-N 3.08Å; G370-F373 PolarHBondContact O-N 2.8Å; G370-A374 WeakPolarHBondContact O-CB 3.33Å; G370-A374 PolarHBondContact O-N 3.43Å
371	G	88.5	Confident	90.3	Very high	9 Å²	9	42.1 Å²	42.1	9%	0.093	22%	0.217	C	C	.	.	H	α-helix	trans	-67.6	-33.5	174.7	0	0	0	0	0	113.9	P368 S375 D401 C402	P368-G371 PolarHBondContact O-N 2.87Å; P368-G371 VanDerWaalsContact O-N 3.12Å; G371-S375 VanDerWaalsContact O-CB 3.27Å; G371-S375 WeakPolarHBondContact O-CB 3.45Å; G371-S375 PolarHBondContact O-N 2.79Å; G371-S375 PolarHBondContact O-OG 3.48Å; G371-D401 WeakPolarHBondContact CA-OD2 3.31Å; G371-C402 PolarHBondContact N-SG 2.94Å
372	F	89.3	Confident	89.6	Confident	20 Å²	20	45.1 Å²	45.1	9%	0.088	23%	0.226	C	C	.	.	H	α-helix	trans	-67.1	-42	172.2	-59.5	-30.8	0	0	0	111.9	L268 I269 K275 P368 F369 S375 G376	L268-F372 HydrophobicContact CD2-CE2 4.17Å; L268-F372 HydrophobicContact CD2-CZ 3.74Å; I269-F372 HydrophobicContact CG2-CD1 4.46Å; I269-F372 HydrophobicContact CG2-CE1 4.43Å; K275-F372 HydrophobicContact CG-CE1 4.18Å; P368-F372 HydrophobicContact CB-CE2 4.21Å; P368-F372 HydrophobicContact CB-CZ 4.19Å; P368-F372 WeakPolarHBondContact O-CG 3.25Å; P368-F372 PolarHBondContact O-N 3.44Å; F369-F372 HydrophobicContact CD1-CD2 4.05Å; F369-F372 HydrophobicContact CE1-CD2 4.46Å; F369-F372 HydrophobicContact CG-CD2 4.22Å; F369-F372 PolarHBondContact O-N 2.9Å; F372-S375 PolarHBondContact O-N 3.06Å; F372-G376 PolarHBondContact O-N 2.87Å
373	F	89.3	Confident	88.8	Confident	143 Å²	143	44 Å²	44	63%	0.627	22%	0.222	S	C	*	.	H	α-helix	trans	-60.9	-50	175.3	177.3	-96	0	0	0	111.3	F369 G370 S375 G376 F377	F369-F373 WeakPolarHBondContact O-CB 3.28Å; F369-F373 PolarHBondContact O-N 3.43Å; G370-F373 PolarHBondContact O-N 2.8Å; F373-S375 VanDerWaalsContact C-N 3.29Å; F373-S375 PolarHBondContact O-N 3.43Å; F373-G376 PolarHBondContact O-N 3.46Å; F373-G376 VanDerWaalsContact O-N 3.1Å; F373-F377 PolarHBondContact O-N 2.97Å
374	A	88	Confident	87.7	Confident	4 Å²	4	51 Å²	51	3%	0.033	25%	0.253	C	S	.	.	H	α-helix	trans	-61.1	-38.7	176.7	0	0	0	0	0	112.1	G370 K378 F386 D401	G370-A374 WeakPolarHBondContact O-CB 3.33Å; G370-A374 PolarHBondContact O-N 3.43Å; A374-K378 WeakPolarHBondContact O-CE 3.37Å; A374-K378 VanDerWaalsContact O-CG 3.3Å; A374-K378 WeakPolarHBondContact O-CG 3.15Å; A374-K378 PolarHBondContact O-N 3.47Å; A374-F386 HydrophobicContact CB-CE2 4.07Å; A374-F386 HydrophobicContact CB-CZ 4.24Å; A374-D401 HydrophobicContact CB-CB 3.52Å; A374-D401 WeakPolarHBondContact CB-OD2 3.44Å
375	S	86.3	Confident	86.8	Confident	28 Å²	28	54 Å²	54	20%	0.196	27%	0.268	C	S	.	.	H	α-helix	trans	-63	-43.2	172.8	-65.1	0	0	0	0	112.1	G371 F372 F373 K378 R379	G371-S375 VanDerWaalsContact O-CB 3.27Å; G371-S375 WeakPolarHBondContact O-CB 3.45Å; G371-S375 PolarHBondContact O-N 2.79Å; G371-S375 PolarHBondContact O-OG 3.48Å; F372-S375 PolarHBondContact O-N 3.06Å; F373-S375 VanDerWaalsContact C-N 3.29Å; F373-S375 PolarHBondContact O-N 3.43Å; S375-K378 PolarHBondContact O-N 3Å; S375-R379 WeakPolarHBondContact O-CG 3.23Å; S375-R379 PolarHBondContact O-N 2.87Å; S375-R379 VanDerWaalsContact O-N 3.08Å
376	G	87.3	Confident	86	Confident	23 Å²	23	51.6 Å²	51.6	24%	0.237	26%	0.255	C	S	.	.	H	α-helix	trans	-61.4	-47	176.9	0	0	0	0	0	112.2	F372 F373 K378 R379 A380	F372-G376 PolarHBondContact O-N 2.87Å; F373-G376 PolarHBondContact O-N 3.46Å; F373-G376 VanDerWaalsContact O-N 3.1Å; G376-K378 VanDerWaalsContact C-N 3.33Å; G376-K378 PolarHBondContact O-N 3.08Å; G376-R379 PolarHBondContact O-N 3.45Å; G376-R379 VanDerWaalsContact O-N 3.13Å; G376-A380 PolarHBondContact O-N 2.89Å
377	F	87.6	Confident	85.3	Confident	47 Å²	47	48.7 Å²	48.7	21%	0.206	24%	0.243	C	C	.	.	H	α-helix	trans	-54.1	-48.9	173.4	177.7	-86.5	0	0	0	111.6	W216 F373 R379 A380 F381 F386	W216-F377 HydrophobicContact CH2-CE1 4.22Å; W216-F377 AromaticContact CH2-CE2 3.56Å; W216-F377 HydrophobicContact CH2-CE2 3.56Å; W216-F377 AromaticContact CH2-CZ 3.15Å; W216-F377 HydrophobicContact CH2-CZ 3.15Å; W216-F377 HydrophobicContact CZ2-CE2 4.34Å; W216-F377 AromaticContact CZ2-CZ 3.63Å; W216-F377 HydrophobicContact CZ2-CZ 3.63Å; W216-F377 AromaticContact CZ3-CE2 3.87Å; W216-F377 HydrophobicContact CZ3-CE2 3.87Å; W216-F377 AromaticContact CZ3-CZ 3.95Å; W216-F377 HydrophobicContact CZ3-CZ 3.95Å; F373-F377 PolarHBondContact O-N 2.97Å; F377-R379 VanDerWaalsContact C-N 3.3Å; F377-R379 PolarHBondContact O-N 3.31Å; F377-A380 WeakPolarHBondContact O-CB 3.18Å; F377-A380 PolarHBondContact O-N 3.4Å; F377-F381 HydrophobicContact CD1-CD2 4.11Å; F377-F381 HydrophobicContact CD1-CE2 4.44Å; F377-F381 HydrophobicContact CD2-CD2 4.28Å; F377-F381 AromaticContact CD2-CE2 3.84Å; F377-F381 HydrophobicContact CD2-CE2 3.84Å; F377-F381 AromaticContact CE1-CD2 3.91Å; F377-F381 HydrophobicContact CE1-CD2 3.91Å; F377-F381 HydrophobicContact CE1-CE2 4.14Å; F377-F381 HydrophobicContact CE2-CD2 4.12Å; F377-F381 AromaticContact CE2-CE2 3.52Å; F377-F381 HydrophobicContact CE2-CE2 3.52Å; F377-F381 HydrophobicContact CE2-CZ 4.48Å; F377-F381 HydrophobicContact CG-CD2 4.31Å; F377-F381 HydrophobicContact CG-CE2 4.32Å; F377-F381 AromaticContact CZ-CD2 3.97Å; F377-F381 HydrophobicContact CZ-CD2 3.97Å; F377-F381 AromaticContact CZ-CE2 3.73Å; F377-F381 HydrophobicContact CZ-CE2 3.73Å; F377-F381 VanDerWaalsContact O-CD2 3.29Å; F377-F381 WeakPolarHBondContact O-CD2 3.31Å; F377-F381 PolarHBondContact O-N 3.14Å; F377-F386 AromaticContact CD1-CE1 3.58Å; F377-F386 HydrophobicContact CD1-CE1 3.58Å; F377-F386 AromaticContact CD1-CZ 3.71Å; F377-F386 HydrophobicContact CD1-CZ 3.71Å; F377-F386 HydrophobicContact CE1-CD1 4.3Å; F377-F386 AromaticContact CE1-CE1 3.44Å; F377-F386 HydrophobicContact CE1-CE1 3.44Å; F377-F386 VanDerWaalsContact CE1-CE1 3.44Å; F377-F386 HydrophobicContact CE1-CZ 4.08Å; F377-F386 HydrophobicContact CZ-CE1 4.4Å
378	K	86.8	Confident	84.6	Confident	19 Å²	19	51 Å²	51	8%	0.083	26%	0.255	C	S	.	.	H	α-helix	trans	-59.6	-39.9	178.3	-73.2	-178.2	-64.1	-177.2	0	112.6	A374 S375 G376 F381 K382 I383 K384 F386 D398	A374-K378 WeakPolarHBondContact O-CE 3.37Å; A374-K378 VanDerWaalsContact O-CG 3.3Å; A374-K378 WeakPolarHBondContact O-CG 3.15Å; A374-K378 PolarHBondContact O-N 3.47Å; S375-K378 PolarHBondContact O-N 3Å; G376-K378 VanDerWaalsContact C-N 3.33Å; G376-K378 PolarHBondContact O-N 3.08Å; K378-F381 PolarHBondContact O-N 3Å; K378-K382 PolarHBondContact O-N 3.47Å; K378-I383 CarbonylContact C-O 3.58Å; K378-I383 HydrophobicContact CB-CD1 4.47Å; K378-I383 HydrophobicContact CB-CG1 3.92Å; K378-I383 HydrophobicContact CG-CD1 4.09Å; K378-I383 HydrophobicContact CG-CG1 4.06Å; K378-I383 VanDerWaalsContact O-CG1 3.29Å; K378-I383 WeakPolarHBondContact O-CG1 3.3Å; K378-I383 PolarHBondContact O-N 3.21Å; K378-K384 WeakPolarHBondContact CD-O 3.37Å; K378-K384 PolarHBondContact NZ-O 3.33Å; K378-F386 HydrophobicContact CD-CD2 3.7Å; K378-F386 HydrophobicContact CD-CE2 3.59Å; K378-F386 HydrophobicContact CD-CZ 4.36Å; K378-F386 HydrophobicContact CG-CD2 4.1Å; K378-F386 HydrophobicContact CG-CE2 3.72Å; K378-F386 HydrophobicContact CG-CZ 3.98Å; K378-D398 WeakPolarHBondContact CD-OD1 3.41Å; K378-D398 IonicContact NZ-OD1 2.68Å; K378-D398 PolarHBondContact NZ-OD1 2.79Å
379	R	85.8	Confident	84	Confident	145 Å²	145	52.7 Å²	52.7	55%	0.547	27%	0.266	S	S	.	.	H	α-helix	trans	-67.1	-38.3	176.9	-61.9	-53.7	171.4	-159.6	-6.4	112.8	L271 S375 G376 F377 F381 K382	L271-R379 HydrophobicContact CD1-CB 4.41Å; L271-R379 HydrophobicContact CD1-CG 3.94Å; S375-R379 WeakPolarHBondContact O-CG 3.23Å; S375-R379 PolarHBondContact O-N 2.87Å; S375-R379 VanDerWaalsContact O-N 3.08Å; G376-R379 PolarHBondContact O-N 3.45Å; G376-R379 VanDerWaalsContact O-N 3.13Å; F377-R379 VanDerWaalsContact C-N 3.3Å; F377-R379 PolarHBondContact O-N 3.31Å; R379-F381 PolarHBondContact O-N 2.88Å; R379-K382 PolarHBondContact O-N 3.43Å
380	A	85.3	Confident	83.1	Confident	62 Å²	62	48.9 Å²	48.9	51%	0.512	25%	0.25	S	C	.	.	H	α-helix	trans	-60.1	-35.8	176.4	0	0	0	0	0	112.3	G376 F377	G376-A380 PolarHBondContact O-N 2.89Å; F377-A380 WeakPolarHBondContact O-CB 3.18Å; F377-A380 PolarHBondContact O-N 3.4Å
381	F	82.6	Confident	82	Confident	36 Å²	36	49.6 Å²	49.6	16%	0.158	25%	0.253	C	S	.	.	T	Hydrogen-bonded Turn	trans	-93.6	11.7	176.4	-66	-73.3	0	0	0	114.3	V133 W216 F377 K378 R379 I383	V133-F381 HydrophobicContact CG1-CD1 4.41Å; V133-F381 HydrophobicContact CG1-CE1 4.49Å; V133-F381 HydrophobicContact CG2-CD1 3.89Å; V133-F381 HydrophobicContact CG2-CE1 4.5Å; W216-F381 HydrophobicContact CH2-CD2 4.41Å; W216-F381 HydrophobicContact CH2-CE1 4.32Å; W216-F381 AromaticContact CH2-CE2 3.72Å; W216-F381 HydrophobicContact CH2-CE2 3.72Å; W216-F381 AromaticContact CH2-CZ 3.68Å; W216-F381 HydrophobicContact CH2-CZ 3.68Å; W216-F381 HydrophobicContact CZ3-CE1 4.32Å; W216-F381 AromaticContact CZ3-CE2 3.87Å; W216-F381 HydrophobicContact CZ3-CE2 3.87Å; W216-F381 AromaticContact CZ3-CZ 3.52Å; W216-F381 HydrophobicContact CZ3-CZ 3.52Å; F377-F381 HydrophobicContact CD1-CD2 4.11Å; F377-F381 HydrophobicContact CD1-CE2 4.44Å; F377-F381 HydrophobicContact CD2-CD2 4.28Å; F377-F381 AromaticContact CD2-CE2 3.84Å; F377-F381 HydrophobicContact CD2-CE2 3.84Å; F377-F381 AromaticContact CE1-CD2 3.91Å; F377-F381 HydrophobicContact CE1-CD2 3.91Å; F377-F381 HydrophobicContact CE1-CE2 4.14Å; F377-F381 HydrophobicContact CE2-CD2 4.12Å; F377-F381 AromaticContact CE2-CE2 3.52Å; F377-F381 HydrophobicContact CE2-CE2 3.52Å; F377-F381 HydrophobicContact CE2-CZ 4.48Å; F377-F381 HydrophobicContact CG-CD2 4.31Å; F377-F381 HydrophobicContact CG-CE2 4.32Å; F377-F381 AromaticContact CZ-CD2 3.97Å; F377-F381 HydrophobicContact CZ-CD2 3.97Å; F377-F381 AromaticContact CZ-CE2 3.73Å; F377-F381 HydrophobicContact CZ-CE2 3.73Å; F377-F381 VanDerWaalsContact O-CD2 3.29Å; F377-F381 WeakPolarHBondContact O-CD2 3.31Å; F377-F381 PolarHBondContact O-N 3.14Å; K378-F381 PolarHBondContact O-N 3Å; R379-F381 PolarHBondContact O-N 2.88Å; F381-I383 HydrophobicContact CB-CD1 4.44Å; F381-I383 HydrophobicContact CB-CG1 4.14Å; F381-I383 PolarHBondContact O-N 3.2Å
382	K	82.3	Confident	80.7	Confident	104 Å²	104	50.9 Å²	50.9	45%	0.452	27%	0.267	S	S	.	.	T	Hydrogen-bonded Turn	trans	52.7	28.1	-177.4	-56.8	-179.8	-175.2	172	0	114.2	D55 K378 R379	D55-K382 PolarHBondContact O-NZ 3.01Å; K378-K382 PolarHBondContact O-N 3.47Å; R379-K382 PolarHBondContact O-N 3.43Å
383	I	80.3	Confident	79.7	Confident	18 Å²	18	51.2 Å²	51.2	9%	0.092	27%	0.269	C	S	.	.			trans	-102.1	158.3	174.4	57	172.6	0	0	0	111.2	I61 I129 K378 F381	I61-I383 HydrophobicContact CB-CG2 4.13Å; I61-I383 HydrophobicContact CD1-CG2 3.4Å; I61-I383 HydrophobicContact CG1-CG2 4.32Å; I61-I383 HydrophobicContact CG2-CG2 4.38Å; I129-I383 HydrophobicContact CD1-CD1 3.77Å; I129-I383 HydrophobicContact CG1-CD1 4.3Å; I129-I383 HydrophobicContact CG2-CD1 4.1Å; K378-I383 CarbonylContact C-O 3.58Å; K378-I383 HydrophobicContact CB-CD1 4.47Å; K378-I383 HydrophobicContact CB-CG1 3.92Å; K378-I383 HydrophobicContact CG-CD1 4.09Å; K378-I383 HydrophobicContact CG-CG1 4.06Å; K378-I383 VanDerWaalsContact O-CG1 3.29Å; K378-I383 WeakPolarHBondContact O-CG1 3.3Å; K378-I383 PolarHBondContact O-N 3.21Å; F381-I383 HydrophobicContact CB-CD1 4.44Å; F381-I383 HydrophobicContact CB-CG1 4.14Å; F381-I383 PolarHBondContact O-N 3.2Å
384	K	74.8	Confident	79.2	Confident	147 Å²	147	44.8 Å²	44.8	64%	0.639	24%	0.243	S	C	*	.	S	Bend	trans	-100.1	-42.5	177.7	-173.9	-179.8	173.6	-175.5	0	113.1	K378	K378-K384 WeakPolarHBondContact CD-O 3.37Å; K378-K384 PolarHBondContact NZ-O 3.33Å
385	D	76.9	Confident	79	Confident	62 Å²	62	44.6 Å²	44.6	33%	0.332	24%	0.241	S	C	.	.	S	Bend	trans	-133.2	149.1	-176.4	-57.4	-52.1	0	0	0	107.8	A387	D385-A387 VanDerWaalsContact C-N 3.29Å; D385-A387 PolarHBondContact O-N 3.34Å
386	F	77.1	Confident	79	Confident	11 Å²	11	44.4 Å²	44.4	5%	0.048	24%	0.238	C	C	.	.	S	Bend	trans	-66.9	-34.3	-179.7	-77.4	-93.7	0	0	0	111.5	I126 I129 A374 F377 K378 M397 D398	I126-F386 HydrophobicContact CG1-CD1 4.21Å; I126-F386 HydrophobicContact CG1-CE1 4.32Å; I129-F386 HydrophobicContact CD1-CB 3.99Å; I129-F386 HydrophobicContact CD1-CD1 3.38Å; I129-F386 HydrophobicContact CD1-CE1 4.25Å; I129-F386 HydrophobicContact CD1-CG 4.05Å; I129-F386 WeakPolarHBondContact CD1-O 3.38Å; A374-F386 HydrophobicContact CB-CE2 4.07Å; A374-F386 HydrophobicContact CB-CZ 4.24Å; F377-F386 AromaticContact CD1-CE1 3.58Å; F377-F386 HydrophobicContact CD1-CE1 3.58Å; F377-F386 AromaticContact CD1-CZ 3.71Å; F377-F386 HydrophobicContact CD1-CZ 3.71Å; F377-F386 HydrophobicContact CE1-CD1 4.3Å; F377-F386 AromaticContact CE1-CE1 3.44Å; F377-F386 HydrophobicContact CE1-CE1 3.44Å; F377-F386 VanDerWaalsContact CE1-CE1 3.44Å; F377-F386 HydrophobicContact CE1-CZ 4.08Å; F377-F386 HydrophobicContact CZ-CE1 4.4Å; K378-F386 HydrophobicContact CD-CD2 3.7Å; K378-F386 HydrophobicContact CD-CE2 3.59Å; K378-F386 HydrophobicContact CD-CZ 4.36Å; K378-F386 HydrophobicContact CG-CD2 4.1Å; K378-F386 HydrophobicContact CG-CE2 3.72Å; K378-F386 HydrophobicContact CG-CZ 3.98Å; F386-M397 HydrophobicContact CB-CB 4Å; F386-M397 HydrophobicContact CB-CG 4.49Å; F386-M397 HydrophobicContact CD1-CB 4.23Å; F386-M397 HydrophobicContact CD1-CG 3.83Å; F386-M397 HydrophobicContact CD2-CB 3.93Å; F386-M397 HydrophobicContact CD2-CG 3.7Å; F386-M397 HydrophobicContact CE1-CG 3.92Å; F386-M397 HydrophobicContact CE2-CG 3.8Å; F386-M397 HydrophobicContact CG-CB 3.81Å; F386-M397 HydrophobicContact CG-CG 3.76Å; F386-M397 HydrophobicContact CZ-CE 4.48Å; F386-M397 HydrophobicContact CZ-CG 3.93Å; F386-D398 VanDerWaalsContact CD2-OD1 3.3Å; F386-D398 WeakPolarHBondContact CD2-OD1 3.38Å; F386-D398 PolarHBondContact N-OD2 3.45Å
387	A	79.1	Confident	79	Confident	17 Å²	17	44 Å²	44	14%	0.14	23%	0.23	C	C	.	.			trans	-159.4	173.7	175.6	0	0	0	0	0	111.5	E125 D385 T389 G394 G395	E125-A387 HydrophobicContact CB-CB 4.29Å; E125-A387 HydrophobicContact CG-CB 3.62Å; D385-A387 VanDerWaalsContact C-N 3.29Å; D385-A387 PolarHBondContact O-N 3.34Å; A387-T389 WeakPolarHBondContact CB-OG1 3.34Å; A387-G394 CarbonylContact O-C 3.49Å; A387-G395 WeakPolarHBondContact O-CA 3.31Å; A387-G395 PolarHBondContact O-N 3.4Å
388	N	77.6	Confident	78.8	Confident	48 Å²	48	42.9 Å²	42.9	26%	0.257	23%	0.226	S	C	.	.			trans	-106.5	55.1	166.7	-76.5	-12.6	0	0	0	110.1	S64	S64-N388 WeakPolarHBondContact CB-ND2 3.37Å; S64-N388 PolarHBondContact O-ND2 3.4Å; S64-N388 WeakPolarHBondContact OG-CB 3.48Å; S64-N388 PolarHBondContact OG-ND2 3.31Å; S64-N388 PolarHBondContact OG-OD1 3.39Å
389	T	78.5	Confident	78.8	Confident	45 Å²	45	48 Å²	48	28%	0.276	24%	0.244	S	C	.	.			trans	-77.8	-41.3	-175.8	-60.2	0	0	0	0	111.8	E125 A387 G394 I396	E125-T389 WeakPolarHBondContact OE1-CB 3.2Å; E125-T389 PolarHBondContact OE1-OG1 3.3Å; A387-T389 WeakPolarHBondContact CB-OG1 3.34Å; T389-G394 PolarHBondContact N-O 3.43Å; T389-I396 HydrophobicContact CG2-CD1 3.69Å; T389-I396 HydrophobicContact CG2-CG1 3.91Å
390	I	72	Confident	78.9	Confident	31 Å²	31	43.8 Å²	43.8	16%	0.159	23%	0.23	C	C	.	.	B	Isolated β-bridge	trans	-107.4	114.8	176.6	-52.8	176.8	0	0	0	108.4	M96 G392 H393 G394 I396	M96-I390 HydrophobicContact CE-CD1 3.98Å; M96-I390 HydrophobicContact SD-CD1 4.28Å; M96-I390 HydrophobicContact SD-CG2 4.24Å; I390-G392 PolarHBondContact O-N 3.29Å; I390-H393 HydrophobicContact CB-CB 3.83Å; I390-H393 HydrophobicContact CG2-CB 3.6Å; I390-H393 PolarHBondContact O-N 2.85Å; I390-G394 PolarHBondContact N-O 3.37Å; I390-G394 PolarHBondContact O-N 3.25Å; I390-I396 HydrophobicContact CD1-CG1 4.19Å; I390-I396 HydrophobicContact CG1-CG1 4.33Å
391	P	66.1	Low	78.8	Confident	22 Å²	22	41.8 Å²	41.8	14%	0.143	21%	0.211	C	C	.	.	T	Hydrogen-bonded Turn	trans	-53.6	126.7	-179.2	-25.7	33.2	0	0	0	112.2	L92 H393	L92-P391 HydrophobicContact CD1-CB 3.98Å; L92-P391 HydrophobicContact CD1-CG 4.44Å; L92-P391 VanDerWaalsContact CD1-O 3.24Å; L92-P391 WeakPolarHBondContact CD1-O 3.42Å; P391-H393 PolarHBondContact O-N 3.15Å; P391-H393 PolarHBondContact O-ND1 2.62Å
392	G	62.7	Low	79	Confident	36 Å²	36	40.5 Å²	40.5	37%	0.371	21%	0.206	S	C	.	.	T	Hydrogen-bonded Turn	trans	72.4	-1.8	-178.2	0	0	0	0	0	116	R89 I390	R89-G392 PolarHBondContact NE-O 2.86Å; R89-G392 PolarHBondContact NH1-O 3.13Å; R89-G392 PolarHBondContact NH2-O 3.37Å; I390-G392 PolarHBondContact O-N 3.29Å
393	H	67.8	Low	79.4	Confident	28 Å²	28	36.4 Å²	36.4	13%	0.13	19%	0.189	C	C	.	.	T	Hydrogen-bonded Turn	trans	-122.5	-8.9	-174.5	-73	82.1	0	0	0	115	R89 T93 I390 P391 R399	R89-H393 PolarHBondContact O-CE1 3.09Å; T93-H393 PolarHBondContact OG1-NE2 3.5Å; T93-H393 VanDerWaalsContact OG1-NE2 3.11Å; I390-H393 HydrophobicContact CB-CB 3.83Å; I390-H393 HydrophobicContact CG2-CB 3.6Å; I390-H393 PolarHBondContact O-N 2.85Å; P391-H393 PolarHBondContact O-N 3.15Å; P391-H393 PolarHBondContact O-ND1 2.62Å; H393-R399 PolarHBondContact CD2-NH2 3.03Å; H393-R399 PolarHBondContact O-NE 3.43Å; H393-R399 VanDerWaalsContact O-NE 3.13Å; H393-R399 PolarHBondContact O-NH2 2.94Å
394	G	79	Confident	79.7	Confident	8 Å²	8	36.8 Å²	36.8	8%	0.082	19%	0.189	C	C	.	.	B	Isolated β-bridge	trans	91.2	-153.2	177	0	0	0	0	0	113.3	A387 T389 I390	A387-G394 CarbonylContact O-C 3.49Å; T389-G394 PolarHBondContact N-O 3.43Å; I390-G394 PolarHBondContact N-O 3.37Å; I390-G394 PolarHBondContact O-N 3.25Å
395	G	82.9	Confident	80.5	Confident	0 Å²	0	33.2 Å²	33.2	0%	0	18%	0.176	C	C	.	.			trans	-79.5	163.2	176.9	0	0	0	0	0	111.8	A387 M397 D398	A387-G395 WeakPolarHBondContact O-CA 3.31Å; A387-G395 PolarHBondContact O-N 3.4Å; G395-M397 VanDerWaalsContact C-N 3.34Å; G395-D398 WeakPolarHBondContact CA-OD2 3.41Å; G395-D398 PolarHBondContact N-OD2 3.34Å
396	I	86.9	Confident	81.4	Confident	24 Å²	24	30.3 Å²	30.3	12%	0.123	16%	0.161	C	C	.	.	S	Bend	trans	-69.8	-38.9	169.8	-67	174.5	0	0	0	109.2	I118 K121 E125 T389 I390 D398 R399 F400	I118-I396 HydrophobicContact CG2-CG2 3.88Å; K121-I396 HydrophobicContact CB-CD1 3.63Å; K121-I396 HydrophobicContact CG-CD1 3.96Å; E125-I396 VanDerWaalsContact CD-N 3.34Å; E125-I396 PolarHBondContact OE1-N 3.44Å; E125-I396 PolarHBondContact OE2-N 2.97Å; T389-I396 HydrophobicContact CG2-CD1 3.69Å; T389-I396 HydrophobicContact CG2-CG1 3.91Å; I390-I396 HydrophobicContact CD1-CG1 4.19Å; I390-I396 HydrophobicContact CG1-CG1 4.33Å; I396-D398 PolarHBondContact O-N 3.15Å; I396-R399 WeakPolarHBondContact O-CB 3.37Å; I396-R399 PolarHBondContact O-N 3.16Å; I396-F400 HydrophobicContact CG2-CD2 3.85Å; I396-F400 HydrophobicContact CG2-CE2 4.08Å; I396-F400 WeakPolarHBondContact O-CD2 3.06Å; I396-F400 PolarHBondContact O-N 2.65Å
397	M	86.6	Confident	82.1	Confident	15 Å²	15	30.1 Å²	30.1	7%	0.074	16%	0.162	C	C	.	.	H	α-helix	trans	-58.8	-36.3	176.7	-177.7	60.7	179.9	0	0	112.3	C122 E125 I126 F386 G395 R399 F400 D401 Y404	C122-M397 HydrophobicContact CB-SD 4.39Å; E125-M397 PolarHBondContact OE2-N 2.92Å; I126-M397 HydrophobicContact CD1-CE 3.83Å; I126-M397 HydrophobicContact CD1-CG 4.2Å; I126-M397 HydrophobicContact CD1-SD 3.84Å; I126-M397 HydrophobicContact CG1-CG 4.24Å; F386-M397 HydrophobicContact CB-CB 4Å; F386-M397 HydrophobicContact CB-CG 4.49Å; F386-M397 HydrophobicContact CD1-CB 4.23Å; F386-M397 HydrophobicContact CD1-CG 3.83Å; F386-M397 HydrophobicContact CD2-CB 3.93Å; F386-M397 HydrophobicContact CD2-CG 3.7Å; F386-M397 HydrophobicContact CE1-CG 3.92Å; F386-M397 HydrophobicContact CE2-CG 3.8Å; F386-M397 HydrophobicContact CG-CB 3.81Å; F386-M397 HydrophobicContact CG-CG 3.76Å; F386-M397 HydrophobicContact CZ-CE 4.48Å; F386-M397 HydrophobicContact CZ-CG 3.93Å; G395-M397 VanDerWaalsContact C-N 3.34Å; M397-R399 PolarHBondContact O-N 3.37Å; M397-F400 PolarHBondContact O-N 2.96Å; M397-D401 PolarHBondContact O-N 3.22Å; M397-Y404 HydrophobicContact CE-CD2 4.2Å; M397-Y404 HydrophobicContact CE-CE2 3.73Å; M397-Y404 HydrophobicContact SD-CD2 4.48Å; M397-Y404 HydrophobicContact SD-CE2 3.57Å; M397-Y404 VanDerWaalsContact SD-CE2 3.57Å
398	D	84.6	Confident	82.8	Confident	22 Å²	22	31.5 Å²	31.5	12%	0.118	17%	0.168	C	C	.	.	H	α-helix	trans	-62.7	-12.1	175.6	-67.2	-66.3	0	0	0	114.1	K378 F386 G395 I396	K378-D398 WeakPolarHBondContact CD-OD1 3.41Å; K378-D398 IonicContact NZ-OD1 2.68Å; K378-D398 PolarHBondContact NZ-OD1 2.79Å; F386-D398 VanDerWaalsContact CD2-OD1 3.3Å; F386-D398 WeakPolarHBondContact CD2-OD1 3.38Å; F386-D398 PolarHBondContact N-OD2 3.45Å; G395-D398 WeakPolarHBondContact CA-OD2 3.41Å; G395-D398 PolarHBondContact N-OD2 3.34Å; I396-D398 PolarHBondContact O-N 3.15Å
399	R	86.4	Confident	83.7	Confident	127 Å²	127	31.6 Å²	31.6	48%	0.479	17%	0.166	S	C	.	.	H	α-helix	trans	-106.6	-17.1	-179	-58.9	-62.1	-179.9	164.3	-3.8	113.4	H393 I396 M397	H393-R399 PolarHBondContact CD2-NH2 3.03Å; H393-R399 PolarHBondContact O-NE 3.43Å; H393-R399 VanDerWaalsContact O-NE 3.13Å; H393-R399 PolarHBondContact O-NH2 2.94Å; I396-R399 WeakPolarHBondContact O-CB 3.37Å; I396-R399 PolarHBondContact O-N 3.16Å; M397-R399 PolarHBondContact O-N 3.37Å
400	F	86.8	Confident	84.5	Confident	57 Å²	57	29.5 Å²	29.5	25%	0.25	15%	0.154	C	C	.	.	H	α-helix	trans	-115	0.5	-174.6	-76.5	-84.6	0	0	0	113.4	I118 I396 M397 C402 Q403 Y404	I118-F400 HydrophobicContact CD1-CE1 4.11Å; I118-F400 HydrophobicContact CD1-CE2 3.97Å; I118-F400 HydrophobicContact CD1-CZ 3.48Å; I118-F400 VanDerWaalsContact CD1-CZ 3.48Å; I118-F400 HydrophobicContact CG1-CE2 4.22Å; I118-F400 HydrophobicContact CG1-CZ 4.22Å; I118-F400 HydrophobicContact CG2-CD1 4.27Å; I118-F400 HydrophobicContact CG2-CD2 3.72Å; I118-F400 HydrophobicContact CG2-CE1 4.25Å; I118-F400 HydrophobicContact CG2-CE2 3.7Å; I118-F400 HydrophobicContact CG2-CG 4.04Å; I118-F400 HydrophobicContact CG2-CZ 3.99Å; I396-F400 HydrophobicContact CG2-CD2 3.85Å; I396-F400 HydrophobicContact CG2-CE2 4.08Å; I396-F400 WeakPolarHBondContact O-CD2 3.06Å; I396-F400 PolarHBondContact O-N 2.65Å; M397-F400 PolarHBondContact O-N 2.96Å; F400-C402 PolarHBondContact O-N 2.94Å; F400-Q403 HydrophobicContact CB-CB 4.49Å; F400-Q403 HydrophobicContact CD1-CB 3.98Å; F400-Q403 HydrophobicContact CD1-CG 3.91Å; F400-Q403 WeakPolarHBondContact O-CB 3.29Å; F400-Q403 PolarHBondContact O-N 3.07Å; F400-Y404 HydrophobicContact CB-CE1 4.42Å; F400-Y404 PolarHBondContact O-N 3.16Å
401	D	84.3	Confident	85.6	Confident	20 Å²	20	29.5 Å²	29.5	11%	0.107	15%	0.153	C	C	.	.	H	α-helix	trans	-56.9	-44.4	178.4	54.4	3.8	0	0	0	113.7	G371 A374 M397 Q403	G371-D401 WeakPolarHBondContact CA-OD2 3.31Å; A374-D401 HydrophobicContact CB-CB 3.52Å; A374-D401 WeakPolarHBondContact CB-OD2 3.44Å; M397-D401 PolarHBondContact O-N 3.22Å; D401-Q403 VanDerWaalsContact C-N 3.34Å
402	C	86.5	Confident	87	Confident	8 Å²	8	32 Å²	32	5%	0.054	17%	0.168	C	C	.	.	H	α-helix	trans	-71.6	-28	173.3	-64.4	0	0	0	0	112.9	V249 G371 F400	V249-C402 HydrophobicContact CG1-CB 3.71Å; G371-C402 PolarHBondContact N-SG 2.94Å; F400-C402 PolarHBondContact O-N 2.94Å
403	Q	90.1	Very high	88.5	Confident	18 Å²	18	31.6 Å²	31.6	8%	0.084	16%	0.155	C	C	.	.	H	α-helix	trans	-73.7	-28	-175.4	-60.7	-68.7	-4	0	0	112.3	I246 V249 F400 D401 M406 A407	I246-Q403 PolarHBondContact O-NE2 2.89Å; V249-Q403 HydrophobicContact CG1-CG 4.5Å; F400-Q403 HydrophobicContact CB-CB 4.49Å; F400-Q403 HydrophobicContact CD1-CB 3.98Å; F400-Q403 HydrophobicContact CD1-CG 3.91Å; F400-Q403 WeakPolarHBondContact O-CB 3.29Å; F400-Q403 PolarHBondContact O-N 3.07Å; D401-Q403 VanDerWaalsContact C-N 3.34Å; Q403-M406 WeakPolarHBondContact O-CB 3.43Å; Q403-M406 PolarHBondContact O-N 3.46Å; Q403-A407 PolarHBondContact O-N 3.42Å
404	Y	87.8	Confident	89.7	Confident	27 Å²	27	30.3 Å²	30.3	11%	0.106	15%	0.149	C	C	.	.	H	α-helix	trans	-63.2	-44.7	178.4	-71.6	-18.8	0	0	0	113	C122 I223 Q227 M397 F400 M406 A407 T408	C122-Y404 WeakPolarHBondContact CB-OH 3.44Å; C122-Y404 PolarHBondContact SG-OH 3.02Å; C122-Y404 VanDerWaalsContact SG-OH 3.4Å; I223-Y404 HydrophobicContact CG2-CD2 3.76Å; I223-Y404 HydrophobicContact CG2-CE2 3.92Å; Q227-Y404 HydrophobicContact CB-CD1 3.69Å; Q227-Y404 HydrophobicContact CB-CE1 4.21Å; Q227-Y404 HydrophobicContact CB-CG 4.15Å; Q227-Y404 HydrophobicContact CG-CD1 4.19Å; Q227-Y404 HydrophobicContact CG-CG 4.13Å; Q227-Y404 PolarHBondContact OE1-O 3.34Å; M397-Y404 HydrophobicContact CE-CD2 4.2Å; M397-Y404 HydrophobicContact CE-CE2 3.73Å; M397-Y404 HydrophobicContact SD-CD2 4.48Å; M397-Y404 HydrophobicContact SD-CE2 3.57Å; M397-Y404 VanDerWaalsContact SD-CE2 3.57Å; F400-Y404 HydrophobicContact CB-CE1 4.42Å; F400-Y404 PolarHBondContact O-N 3.16Å; Y404-M406 VanDerWaalsContact C-N 3.27Å; Y404-M406 PolarHBondContact O-N 3.04Å; Y404-A407 PolarHBondContact O-N 3.19Å; Y404-T408 PolarHBondContact O-N 2.9Å
405	L	91.3	Very high	90.2	Very high	71 Å²	71	33 Å²	33	37%	0.372	16%	0.164	S	C	.	.	H	α-helix	trans	-64.6	-36.1	174.2	-69.8	-179.7	0	0	0	111.8	F362 F409	F362-L405 HydrophobicContact CE1-CB 4.5Å; L405-F409 PolarHBondContact O-N 3.04Å; L405-F409 VanDerWaalsContact O-N 3.16Å
406	M	94.6	Very high	90.5	Very high	2 Å²	2	36.6 Å²	36.6	1%	0.01	19%	0.189	C	C	.	.	H	α-helix	trans	-64.6	-42.1	178.7	-166.5	63.3	-167.3	0	0	112	P245 V249 L359 F362 A363 Q403 Y404 T408 F409 V410	P245-M406 HydrophobicContact CB-CE 3.52Å; P245-M406 HydrophobicContact CB-CG 3.79Å; P245-M406 HydrophobicContact CB-SD 4.48Å; P245-M406 HydrophobicContact CG-CE 4.04Å; V249-M406 HydrophobicContact CG2-CB 4.06Å; V249-M406 HydrophobicContact CG2-CG 3.96Å; V249-M406 HydrophobicContact CG2-SD 4.42Å; L359-M406 HydrophobicContact CB-CE 3.95Å; L359-M406 HydrophobicContact CD2-CE 4.35Å; L359-M406 VanDerWaalsContact O-CE 3.29Å; L359-M406 WeakPolarHBondContact O-CE 3.5Å; F362-M406 HydrophobicContact CD1-SD 3.68Å; F362-M406 HydrophobicContact CE1-SD 4.3Å; A363-M406 HydrophobicContact CB-CE 4.1Å; A363-M406 HydrophobicContact CB-SD 3.83Å; Q403-M406 WeakPolarHBondContact O-CB 3.43Å; Q403-M406 PolarHBondContact O-N 3.46Å; Y404-M406 VanDerWaalsContact C-N 3.27Å; Y404-M406 PolarHBondContact O-N 3.04Å; M406-T408 PolarHBondContact O-N 3.34Å; M406-F409 HydrophobicContact CE-CD1 4.25Å; M406-F409 PolarHBondContact O-N 2.94Å; M406-F409 HydrophobicContact SD-CD1 4.4Å; M406-V410 HydrophobicContact CE-CG2 3.72Å; M406-V410 HydrophobicContact CG-CG2 4.22Å; M406-V410 VanDerWaalsContact O-CG2 3.24Å; M406-V410 WeakPolarHBondContact O-CG2 3.34Å; M406-V410 PolarHBondContact O-N 3Å; M406-V410 HydrophobicContact SD-CG2 4.49Å
407	A	92.7	Very high	90.6	Very high	7 Å²	7	42.1 Å²	42.1	6%	0.058	21%	0.213	C	C	.	.	H	α-helix	trans	-56.6	-48.5	179.2	0	0	0	0	0	112.8	V231 N234 Q403 Y404 H411	V231-A407 HydrophobicContact CG2-CB 3.35Å; N234-A407 PolarHBondContact ND2-O 3.23Å; N234-A407 VanDerWaalsContact ND2-O 3.12Å; Q403-A407 PolarHBondContact O-N 3.42Å; Y404-A407 PolarHBondContact O-N 3.19Å; A407-H411 PolarHBondContact O-N 2.97Å
408	T	94	Very high	90.7	Very high	46 Å²	46	43.6 Å²	43.6	28%	0.282	22%	0.22	S	C	.	.	H	α-helix	trans	-64.3	-44.4	178	-63.3	0	0	0	0	110.9	Q227 L230 Y404 M406 V410 H411 V412	Q227-T408 PolarHBondContact NE2-OG1 2.97Å; Q227-T408 PolarHBondContact OE1-OG1 3.45Å; L230-T408 HydrophobicContact CD1-CG2 4.3Å; Y404-T408 PolarHBondContact O-N 2.9Å; M406-T408 PolarHBondContact O-N 3.34Å; T408-V410 PolarHBondContact O-N 3.11Å; T408-H411 PolarHBondContact O-N 3.41Å; T408-V412 HydrophobicContact CG2-CG2 4.33Å; T408-V412 WeakPolarHBondContact O-CG2 3.32Å; T408-V412 PolarHBondContact O-N 3.31Å
409	F	96.1	Very high	90.3	Very high	49 Å²	49	47 Å²	47	22%	0.215	23%	0.232	C	C	.	.	H	α-helix	trans	-61.1	-47.2	-179.8	176.4	-108.2	0	0	0	112.5	L359 F362 L405 M406 H411 V412 Y413	L359-F409 HydrophobicContact CD2-CD1 4.26Å; L359-F409 HydrophobicContact CD2-CE1 3.87Å; F362-F409 HydrophobicContact CB-CD1 3.58Å; F362-F409 HydrophobicContact CB-CE1 3.33Å; F362-F409 HydrophobicContact CB-CE2 4.31Å; F362-F409 HydrophobicContact CB-CG 4.17Å; F362-F409 HydrophobicContact CB-CZ 3.73Å; F362-F409 HydrophobicContact CD1-CB 3.71Å; F362-F409 AromaticContact CD1-CD1 3.49Å; F362-F409 HydrophobicContact CD1-CD1 3.49Å; F362-F409 VanDerWaalsContact CD1-CD1 3.49Å; F362-F409 HydrophobicContact CD1-CD2 4.3Å; F362-F409 HydrophobicContact CD1-CE1 4.18Å; F362-F409 AromaticContact CD1-CG 3.55Å; F362-F409 HydrophobicContact CD1-CG 3.55Å; F362-F409 HydrophobicContact CD2-CB 4.25Å; F362-F409 AromaticContact CD2-CD1 3.91Å; F362-F409 HydrophobicContact CD2-CD1 3.91Å; F362-F409 AromaticContact CD2-CD2 3.43Å; F362-F409 HydrophobicContact CD2-CD2 3.43Å; F362-F409 VanDerWaalsContact CD2-CD2 3.43Å; F362-F409 HydrophobicContact CD2-CE1 4.08Å; F362-F409 AromaticContact CD2-CE2 3.64Å; F362-F409 HydrophobicContact CD2-CE2 3.64Å; F362-F409 AromaticContact CD2-CG 3.57Å; F362-F409 HydrophobicContact CD2-CG 3.57Å; F362-F409 AromaticContact CD2-CZ 3.96Å; F362-F409 HydrophobicContact CD2-CZ 3.96Å; F362-F409 HydrophobicContact CE1-CB 3.4Å; F362-F409 VanDerWaalsContact CE1-CB 3.4Å; F362-F409 HydrophobicContact CE1-CD1 4.13Å; F362-F409 HydrophobicContact CE1-CD2 4.42Å; F362-F409 AromaticContact CE1-CG 3.74Å; F362-F409 HydrophobicContact CE1-CG 3.74Å; F362-F409 HydrophobicContact CE2-CB 3.97Å; F362-F409 HydrophobicContact CE2-CD1 4.48Å; F362-F409 AromaticContact CE2-CD2 3.57Å; F362-F409 HydrophobicContact CE2-CD2 3.57Å; F362-F409 HydrophobicContact CE2-CE2 4.18Å; F362-F409 AromaticContact CE2-CG 3.74Å; F362-F409 HydrophobicContact CE2-CG 3.74Å; F362-F409 HydrophobicContact CG-CB 4.13Å; F362-F409 AromaticContact CG-CD1 3.36Å; F362-F409 HydrophobicContact CG-CD1 3.36Å; F362-F409 AromaticContact CG-CD2 3.82Å; F362-F409 HydrophobicContact CG-CD2 3.82Å; F362-F409 AromaticContact CG-CE1 3.61Å; F362-F409 HydrophobicContact CG-CE1 3.61Å; F362-F409 HydrophobicContact CG-CE2 4.05Å; F362-F409 AromaticContact CG-CG 3.47Å; F362-F409 HydrophobicContact CG-CG 3.47Å; F362-F409 VanDerWaalsContact CG-CG 3.47Å; F362-F409 AromaticContact CG-CZ 3.94Å; F362-F409 HydrophobicContact CG-CZ 3.94Å; F362-F409 HydrophobicContact CZ-CB 3.54Å; F362-F409 HydrophobicContact CZ-CD2 4.08Å; F362-F409 AromaticContact CZ-CG 3.82Å; F362-F409 HydrophobicContact CZ-CG 3.82Å; L405-F409 PolarHBondContact O-N 3.04Å; L405-F409 VanDerWaalsContact O-N 3.16Å; M406-F409 HydrophobicContact CE-CD1 4.25Å; M406-F409 PolarHBondContact O-N 2.94Å; M406-F409 HydrophobicContact SD-CD1 4.4Å; F409-H411 VanDerWaalsContact C-N 3.27Å; F409-H411 PolarHBondContact O-N 2.9Å; F409-V412 PolarHBondContact O-N 3.18Å; F409-Y413 HydrophobicContact CE1-CD2 4.38Å; F409-Y413 HydrophobicContact CE2-CD2 4.42Å; F409-Y413 AromaticContact CZ-CD2 3.86Å; F409-Y413 HydrophobicContact CZ-CD2 3.86Å; F409-Y413 WeakPolarHBondContact O-CB 3.36Å; F409-Y413 PolarHBondContact O-N 3.37Å
410	V	96.4	Very high	89.3	Confident	2 Å²	2	43.5 Å²	43.5	1%	0.012	24%	0.235	C	C	.	.	H	α-helix	trans	-58.2	-43.8	178.1	174.4	0	0	0	0	110.5	N234 W241 P245 L359 M406 T408 Y413 I414	N234-V410 HydrophobicContact CB-CG1 4.1Å; N234-V410 WeakPolarHBondContact ND2-CG1 3.46Å; W241-V410 HydrophobicContact CE3-CG1 4.3Å; P245-V410 HydrophobicContact CB-CG2 3.63Å; P245-V410 HydrophobicContact CG-CG1 4.32Å; P245-V410 HydrophobicContact CG-CG2 3.41Å; P245-V410 VanDerWaalsContact CG-CG2 3.41Å; L359-V410 HydrophobicContact CD2-CG2 4.16Å; M406-V410 HydrophobicContact CE-CG2 3.72Å; M406-V410 HydrophobicContact CG-CG2 4.22Å; M406-V410 VanDerWaalsContact O-CG2 3.24Å; M406-V410 WeakPolarHBondContact O-CG2 3.34Å; M406-V410 PolarHBondContact O-N 3Å; M406-V410 HydrophobicContact SD-CG2 4.49Å; T408-V410 PolarHBondContact O-N 3.11Å; V410-Y413 PolarHBondContact O-N 3.45Å; V410-I414 HydrophobicContact CG1-CD1 3.71Å; V410-I414 HydrophobicContact CG1-CG1 4.33Å; V410-I414 VanDerWaalsContact O-CG1 3.29Å; V410-I414 WeakPolarHBondContact O-CG1 3.26Å; V410-I414 PolarHBondContact O-N 3.49Å
411	H	94.9	Very high	88	Confident	31 Å²	31	46.4 Å²	46.4	14%	0.144	26%	0.26	C	S	.	.	H	α-helix	trans	-64.5	-47	-179.3	-173.6	78	0	0	0	112.7	L230 Q233 N234 A407 T408 F409 Y413 I414 T415	L230-H411 HydrophobicContact CB-CB 4.29Å; L230-H411 HydrophobicContact CD2-CB 4.19Å; Q233-H411 PolarHBondContact OE1-CE1 3.4Å; Q233-H411 PolarHBondContact OE1-ND1 3.16Å; N234-H411 PolarHBondContact ND2-N 3.26Å; N234-H411 WeakPolarHBondContact OD1-CA 3.21Å; N234-H411 VanDerWaalsContact OD1-CB 3.3Å; N234-H411 WeakPolarHBondContact OD1-CB 3.39Å; N234-H411 PolarHBondContact OD1-ND1 3.38Å; A407-H411 PolarHBondContact O-N 2.97Å; T408-H411 PolarHBondContact O-N 3.41Å; F409-H411 VanDerWaalsContact C-N 3.27Å; F409-H411 PolarHBondContact O-N 2.9Å; H411-Y413 VanDerWaalsContact C-N 3.28Å; H411-Y413 PolarHBondContact O-N 3.24Å; H411-I414 PolarHBondContact O-N 3.24Å; H411-T415 WeakPolarHBondContact O-CB 3.37Å; H411-T415 PolarHBondContact O-N 2.84Å; H411-T415 PolarHBondContact O-OG1 3.48Å
412	V	94.8	Very high	87	Confident	75 Å²	75	49.8 Å²	49.8	46%	0.455	28%	0.277	S	S	.	.	H	α-helix	trans	-61.4	-41.3	175.2	172.1	0	0	0	0	110.2	T408 F409 T415 S416	T408-V412 HydrophobicContact CG2-CG2 4.33Å; T408-V412 WeakPolarHBondContact O-CG2 3.32Å; T408-V412 PolarHBondContact O-N 3.31Å; F409-V412 PolarHBondContact O-N 3.18Å; V412-T415 PolarHBondContact O-N 2.95Å; V412-S416 VanDerWaalsContact O-CB 3.24Å; V412-S416 WeakPolarHBondContact O-CB 3.43Å; V412-S416 PolarHBondContact O-N 2.85Å; V412-S416 PolarHBondContact O-OG 3.43Å
413	Y	95.2	Very high	86	Confident	26 Å²	26	54.2 Å²	54.2	10%	0.102	31%	0.306	C	S	.	.	H	α-helix	trans	-63.3	-48.2	179.4	-169.6	-87.4	0	0	0	111.9	W241 H355 A358 L359 F409 V410 H411 T415 S416 F417 I418	W241-Y413 HydrophobicContact CZ3-CD1 4.38Å; H355-Y413 HydrophobicContact CB-CE1 3.97Å; H355-Y413 AromaticContact ND1-CE1 3.54Å; H355-Y413 AromaticContact ND1-CZ 3.62Å; H355-Y413 PolarHBondContact ND1-OH 3.49Å; A358-Y413 HydrophobicContact CB-CE2 3.71Å; L359-Y413 HydrophobicContact CD2-CD1 4.15Å; L359-Y413 HydrophobicContact CD2-CG 4.21Å; F409-Y413 HydrophobicContact CE1-CD2 4.38Å; F409-Y413 HydrophobicContact CE2-CD2 4.42Å; F409-Y413 AromaticContact CZ-CD2 3.86Å; F409-Y413 HydrophobicContact CZ-CD2 3.86Å; F409-Y413 WeakPolarHBondContact O-CB 3.36Å; F409-Y413 PolarHBondContact O-N 3.37Å; V410-Y413 PolarHBondContact O-N 3.45Å; H411-Y413 VanDerWaalsContact C-N 3.28Å; H411-Y413 PolarHBondContact O-N 3.24Å; Y413-T415 PolarHBondContact O-N 3.46Å; Y413-S416 PolarHBondContact O-N 3.35Å; Y413-F417 HydrophobicContact CD1-CD2 4.41Å; Y413-F417 AromaticContact CD2-CD2 3.52Å; Y413-F417 HydrophobicContact CD2-CD2 3.52Å; Y413-F417 AromaticContact CD2-CE2 3.86Å; Y413-F417 HydrophobicContact CD2-CE2 3.86Å; Y413-F417 HydrophobicContact CE1-CB 4.4Å; Y413-F417 HydrophobicContact CE1-CD2 4.49Å; Y413-F417 AromaticContact CE2-CD2 3.61Å; Y413-F417 HydrophobicContact CE2-CD2 3.61Å; Y413-F417 AromaticContact CE2-CE2 4Å; Y413-F417 HydrophobicContact CE2-CE2 4Å; Y413-F417 HydrophobicContact CE2-CG 4.36Å; Y413-F417 AromaticContact CG-CD2 3.94Å; Y413-F417 HydrophobicContact CG-CD2 3.94Å; Y413-F417 WeakPolarHBondContact O-CB 3.28Å; Y413-F417 PolarHBondContact O-N 3.2Å; Y413-I418 HydrophobicContact CD1-CG1 4.36Å; Y413-I418 HydrophobicContact CE1-CD1 4.24Å; Y413-I418 HydrophobicContact CE1-CG1 4.36Å
414	I	91.8	Very high	84.5	Confident	2 Å²	2	57 Å²	57	1%	0.01	33%	0.328	C	S	.	.	I	π-helix	trans	-58.5	-50.8	175.5	-69.3	167	0	0	0	109.7	N234 E237 W241 V410 H411 S416 I418 R419	N234-I414 HydrophobicContact CB-CD1 4.28Å; E237-I414 HydrophobicContact CG-CG2 4.49Å; W241-I414 HydrophobicContact CB-CD1 3.88Å; W241-I414 HydrophobicContact CD2-CD1 3.53Å; W241-I414 HydrophobicContact CD2-CG1 3.74Å; W241-I414 HydrophobicContact CE3-CD1 3.61Å; W241-I414 HydrophobicContact CE3-CG1 3.52Å; W241-I414 HydrophobicContact CG-CD1 3.65Å; W241-I414 HydrophobicContact CG-CG1 4.38Å; W241-I414 HydrophobicContact CH2-CG1 4.16Å; W241-I414 HydrophobicContact CZ2-CG1 4.32Å; W241-I414 HydrophobicContact CZ3-CD1 4.34Å; W241-I414 HydrophobicContact CZ3-CG1 3.74Å; V410-I414 HydrophobicContact CG1-CD1 3.71Å; V410-I414 HydrophobicContact CG1-CG1 4.33Å; V410-I414 VanDerWaalsContact O-CG1 3.29Å; V410-I414 WeakPolarHBondContact O-CG1 3.26Å; V410-I414 PolarHBondContact O-N 3.49Å; H411-I414 PolarHBondContact O-N 3.24Å; I414-S416 VanDerWaalsContact C-N 3.28Å; I414-S416 PolarHBondContact O-N 3.31Å; I414-I418 HydrophobicContact CG2-CB 4.35Å; I414-I418 CarbonylContact O-C 3.23Å; I414-I418 WeakPolarHBondContact O-CA 3.46Å; I414-I418 WeakPolarHBondContact O-CB 3.46Å; I414-I418 PolarHBondContact O-N 2.99Å; I414-R419 HydrophobicContact CG2-CG 3.92Å; I414-R419 PolarHBondContact O-N 2.89Å
415	T	89.5	Confident	83.3	Confident	65 Å²	65	60.8 Å²	60.8	40%	0.399	35%	0.345	S	S	.	.	I	π-helix	trans	-65.5	-30.6	-176.8	-60	0	0	0	0	113	H411 V412 Y413	H411-T415 WeakPolarHBondContact O-CB 3.37Å; H411-T415 PolarHBondContact O-N 2.84Å; H411-T415 PolarHBondContact O-OG1 3.48Å; V412-T415 PolarHBondContact O-N 2.95Å; Y413-T415 PolarHBondContact O-N 3.46Å
416	S	90.3	Very high	82.5	Confident	75 Å²	75	60.5 Å²	60.5	52%	0.524	35%	0.346	S	S	.	.	I	π-helix	trans	-88.7	-39	-177.1	-51	0	0	0	0	113.6	V412 Y413 I414	V412-S416 VanDerWaalsContact O-CB 3.24Å; V412-S416 WeakPolarHBondContact O-CB 3.43Å; V412-S416 PolarHBondContact O-N 2.85Å; V412-S416 PolarHBondContact O-OG 3.43Å; Y413-S416 PolarHBondContact O-N 3.35Å; I414-S416 VanDerWaalsContact C-N 3.28Å; I414-S416 PolarHBondContact O-N 3.31Å
417	F	89.2	Confident	81.7	Confident	140 Å²	140	65.1 Å²	65.1	61%	0.614	37%	0.37	S	S	*	.	I	π-helix	trans	-115.3	-18.5	-168	-60.4	-70.4	0	0	0	114.2	Y413	Y413-F417 HydrophobicContact CD1-CD2 4.41Å; Y413-F417 AromaticContact CD2-CD2 3.52Å; Y413-F417 HydrophobicContact CD2-CD2 3.52Å; Y413-F417 AromaticContact CD2-CE2 3.86Å; Y413-F417 HydrophobicContact CD2-CE2 3.86Å; Y413-F417 HydrophobicContact CE1-CB 4.4Å; Y413-F417 HydrophobicContact CE1-CD2 4.49Å; Y413-F417 AromaticContact CE2-CD2 3.61Å; Y413-F417 HydrophobicContact CE2-CD2 3.61Å; Y413-F417 AromaticContact CE2-CE2 4Å; Y413-F417 HydrophobicContact CE2-CE2 4Å; Y413-F417 HydrophobicContact CE2-CG 4.36Å; Y413-F417 AromaticContact CG-CD2 3.94Å; Y413-F417 HydrophobicContact CG-CD2 3.94Å; Y413-F417 WeakPolarHBondContact O-CB 3.28Å; Y413-F417 PolarHBondContact O-N 3.2Å
418	I	87.6	Confident	80.6	Confident	45 Å²	45	71.1 Å²	71.1	23%	0.231	40%	0.397	C	S	.	.	I	π-helix	trans	-113.8	-50.7	-171.7	-50.9	-64.3	0	0	0	111.4	W241 L326 H355 Y413 I414 G420	W241-I418 HydrophobicContact CH2-CB 4.5Å; W241-I418 HydrophobicContact CH2-CD1 3.76Å; W241-I418 HydrophobicContact CH2-CG1 3.55Å; W241-I418 HydrophobicContact CH2-CG2 4.37Å; W241-I418 HydrophobicContact CZ2-CB 4.43Å; W241-I418 HydrophobicContact CZ2-CD1 4.24Å; W241-I418 HydrophobicContact CZ2-CG1 3.94Å; W241-I418 HydrophobicContact CZ2-CG2 3.87Å; W241-I418 HydrophobicContact CZ3-CG1 4.43Å; L326-I418 HydrophobicContact CD1-CD1 4.13Å; L326-I418 HydrophobicContact CD2-CD1 4.38Å; L326-I418 HydrophobicContact CD2-CG2 4.08Å; H355-I418 VanDerWaalsContact CE1-CD1 3.49Å; H355-I418 WeakPolarHBondContact CE1-CD1 3.43Å; Y413-I418 HydrophobicContact CD1-CG1 4.36Å; Y413-I418 HydrophobicContact CE1-CD1 4.24Å; Y413-I418 HydrophobicContact CE1-CG1 4.36Å; I414-I418 HydrophobicContact CG2-CB 4.35Å; I414-I418 CarbonylContact O-C 3.23Å; I414-I418 WeakPolarHBondContact O-CA 3.46Å; I414-I418 WeakPolarHBondContact O-CB 3.46Å; I414-I418 PolarHBondContact O-N 2.99Å; I418-G420 PolarHBondContact O-N 3.08Å
419	R	76.4	Confident	79.8	Confident	94 Å²	94	74.7 Å²	74.7	36%	0.355	41%	0.41	S	S	.	.			trans	-70.2	100.7	-179.9	-85.2	-179.9	174.5	171.4	-8.9	109.6	Y165 E237 I414	Y165-R419 PolarHBondContact OH-NH2 3.4Å; E237-R419 IonicContact OE1-CZ 3.55Å; E237-R419 IonicContact OE1-NE 3.64Å; E237-R419 IonicContact OE1-NH2 2.67Å; E237-R419 PolarHBondContact OE1-NH2 3.21Å; E237-R419 IonicContact OE2-CZ 3.65Å; E237-R419 IonicContact OE2-NE 2.98Å; E237-R419 PolarHBondContact OE2-NE 3.49Å; E237-R419 IonicContact OE2-NH2 3.53Å; I414-R419 HydrophobicContact CG2-CG 3.92Å; I414-R419 PolarHBondContact O-N 2.89Å
420	G	66.3	Low	79.2	Confident	53 Å²	53	74.7 Å²	74.7	55%	0.546	41%	0.412	S	S	.	.			trans	-74.4	164	156	0	0	0	0	0	111.2	I418 N422	I418-G420 PolarHBondContact O-N 3.08Å; G420-N422 PolarHBondContact O-N 3.22Å; G420-N422 VanDerWaalsContact O-N 3.07Å
421	P	59.2	Low	78.5	Confident	119 Å²	119	79.9 Å²	79.9	77%	0.773	44%	0.44	S	S	*	.			trans	-60.4	113.3	172.3	23.4	-30.7	0	0	0	109.9	P423	P421-P423 WeakPolarHBondContact O-CD 3.43Å
422	N	61.6	Low	77.9	Confident	90 Å²	90	84.6 Å²	84.6	48%	0.481	47%	0.47	S	S	.	.			trans	-69.9	113.1	177.9	-178.3	-29.1	0	0	0	109.4	G420 S424 K425 V426	G420-N422 PolarHBondContact O-N 3.22Å; G420-N422 VanDerWaalsContact O-N 3.07Å; N422-S424 PolarHBondContact O-N 2.73Å; N422-S424 VanDerWaalsContact OD1-CB 3.31Å; N422-S424 WeakPolarHBondContact OD1-CB 3.49Å; N422-S424 PolarHBondContact OD1-N 2.98Å; N422-K425 HydrophobicContact CB-CB 4.07Å; N422-K425 PolarHBondContact O-N 3.45Å; N422-K425 VanDerWaalsContact O-N 3.14Å; N422-K425 PolarHBondContact OD1-N 3.33Å; N422-V426 WeakPolarHBondContact O-CG2 3.4Å; N422-V426 PolarHBondContact O-N 3.21Å
423	P	67	Low	77.4	Confident	101 Å²	101	84 Å²	84	66%	0.656	46%	0.464	S	S	*	.	H	α-helix	trans	-59.5	-34.2	-176.2	-22.7	34	0	0	0	112.9	P421 V426 L427	P421-P423 WeakPolarHBondContact O-CD 3.43Å; P423-V426 PolarHBondContact O-N 2.87Å; P423-L427 VanDerWaalsContact O-CB 3.28Å; P423-L427 WeakPolarHBondContact O-CB 3.38Å; P423-L427 PolarHBondContact O-N 3.37Å
424	S	58.8	Low	77.2	Confident	77 Å²	77	89 Å²	89	54%	0.538	49%	0.488	S	S	.	.	H	α-helix	trans	-69	-39.7	179.3	-52	0	0	0	0	111.8	N422 L427 Q428	N422-S424 PolarHBondContact O-N 2.73Å; N422-S424 VanDerWaalsContact OD1-CB 3.31Å; N422-S424 WeakPolarHBondContact OD1-CB 3.49Å; N422-S424 PolarHBondContact OD1-N 2.98Å; S424-L427 PolarHBondContact O-N 3.46Å; S424-Q428 WeakPolarHBondContact O-CG 3.44Å; S424-Q428 PolarHBondContact O-N 3.35Å
425	K	61.2	Low	77.2	Confident	106 Å²	106	93.8 Å²	93.8	46%	0.461	52%	0.52	S	S	.	.	H	α-helix	trans	-68.7	-40.9	175.7	-169	172	-176.2	169.3	0	111.2	N422 L427 Q428 Q429	N422-K425 HydrophobicContact CB-CB 4.07Å; N422-K425 PolarHBondContact O-N 3.45Å; N422-K425 VanDerWaalsContact O-N 3.14Å; N422-K425 PolarHBondContact OD1-N 3.33Å; K425-L427 VanDerWaalsContact C-N 3.33Å; K425-Q428 PolarHBondContact O-N 3Å; K425-Q429 WeakPolarHBondContact O-CG 3.44Å; K425-Q429 PolarHBondContact O-N 3.23Å
426	V	74.9	Confident	77.3	Confident	65 Å²	65	98.2 Å²	98.2	39%	0.394	54%	0.535	S	S	.	.	H	α-helix	trans	-60.2	-45.9	172.5	175	0	0	0	0	109.9	N422 P423 Q429 L430	N422-V426 WeakPolarHBondContact O-CG2 3.4Å; N422-V426 PolarHBondContact O-N 3.21Å; P423-V426 PolarHBondContact O-N 2.87Å; V426-Q429 PolarHBondContact O-N 2.9Å; V426-L430 HydrophobicContact CG1-CD1 4.16Å; V426-L430 HydrophobicContact CG1-CG 4.48Å; V426-L430 VanDerWaalsContact O-CG 3.26Å; V426-L430 WeakPolarHBondContact O-CG 3.48Å; V426-L430 PolarHBondContact O-N 2.93Å
427	L	77.7	Confident	77.4	Confident	99 Å²	99	99.2 Å²	99.2	52%	0.518	53%	0.532	S	S	.	.	H	α-helix	trans	-62.4	-44.6	177.8	-175.8	63.5	0	0	0	112.2	P423 S424 K425 Q429 L430 L431	P423-L427 VanDerWaalsContact O-CB 3.28Å; P423-L427 WeakPolarHBondContact O-CB 3.38Å; P423-L427 PolarHBondContact O-N 3.37Å; S424-L427 PolarHBondContact O-N 3.46Å; K425-L427 VanDerWaalsContact C-N 3.33Å; L427-Q429 VanDerWaalsContact C-N 3.33Å; L427-Q429 PolarHBondContact O-N 3.43Å; L427-L430 WeakPolarHBondContact O-CB 3.26Å; L427-L430 PolarHBondContact O-N 3.47Å; L427-L430 VanDerWaalsContact O-N 3.16Å; L427-L431 HydrophobicContact CD1-CG 4.48Å; L427-L431 HydrophobicContact CG-CD1 4.14Å; L427-L431 HydrophobicContact CG-CG 4.44Å; L427-L431 VanDerWaalsContact O-CG 3.27Å; L427-L431 WeakPolarHBondContact O-CG 3.36Å; L427-L431 PolarHBondContact O-N 3.06Å
428	Q	70.6	Confident	77.5	Confident	133 Å²	133	95.5 Å²	95.5	62%	0.621	52%	0.517	S	S	*	.	H	α-helix	trans	-60.3	-42.5	175.4	-78.1	179.3	-7.6	0	0	112	S424 K425 L430 L431 V432	S424-Q428 WeakPolarHBondContact O-CG 3.44Å; S424-Q428 PolarHBondContact O-N 3.35Å; K425-Q428 PolarHBondContact O-N 3Å; Q428-L430 VanDerWaalsContact C-N 3.3Å; Q428-L430 PolarHBondContact O-N 2.87Å; Q428-L431 PolarHBondContact O-N 3.47Å; Q428-V432 WeakPolarHBondContact O-CG2 3.13Å; Q428-V432 PolarHBondContact O-N 2.87Å
429	Q	75.8	Confident	77.7	Confident	122 Å²	122	97.9 Å²	97.9	57%	0.57	53%	0.529	S	S	*	.	H	α-helix	trans	-61.4	-40.4	174.6	-73.6	177	-15.7	0	0	111.8	K425 V426 L427 V432	K425-Q429 WeakPolarHBondContact O-CG 3.44Å; K425-Q429 PolarHBondContact O-N 3.23Å; V426-Q429 PolarHBondContact O-N 2.9Å; L427-Q429 VanDerWaalsContact C-N 3.33Å; L427-Q429 PolarHBondContact O-N 3.43Å; Q429-V432 PolarHBondContact O-N 3.28Å
430	L	83.2	Confident	78.6	Confident	49 Å²	49	98.3 Å²	98.3	26%	0.257	54%	0.539	S	S	.	.	H	α-helix	trans	-63.3	-42.3	174.9	-68.5	173.4	0	0	0	111.7	V426 L427 Q428 V432 L433 Q438 I441	V426-L430 HydrophobicContact CG1-CD1 4.16Å; V426-L430 HydrophobicContact CG1-CG 4.48Å; V426-L430 VanDerWaalsContact O-CG 3.26Å; V426-L430 WeakPolarHBondContact O-CG 3.48Å; V426-L430 PolarHBondContact O-N 2.93Å; L427-L430 WeakPolarHBondContact O-CB 3.26Å; L427-L430 PolarHBondContact O-N 3.47Å; L427-L430 VanDerWaalsContact O-N 3.16Å; Q428-L430 VanDerWaalsContact C-N 3.3Å; Q428-L430 PolarHBondContact O-N 2.87Å; L430-V432 PolarHBondContact O-N 3.45Å; L430-L433 HydrophobicContact CD2-CD1 4.02Å; L430-L433 WeakPolarHBondContact O-CB 3.35Å; L430-L433 PolarHBondContact O-N 2.86Å; L430-L433 VanDerWaalsContact O-N 3.1Å; L430-Q438 VanDerWaalsContact O-CG 3.3Å; L430-Q438 WeakPolarHBondContact O-CG 3.41Å; L430-Q438 PolarHBondContact O-NE2 3.01Å; L430-I441 HydrophobicContact CD1-CG2 4.41Å; L430-I441 HydrophobicContact CD2-CB 4.39Å; L430-I441 HydrophobicContact CD2-CD1 3.41Å; L430-I441 VanDerWaalsContact CD2-CD1 3.41Å; L430-I441 HydrophobicContact CD2-CG1 4.43Å; L430-I441 HydrophobicContact CD2-CG2 3.8Å
431	L	82.2	Confident	79.9	Confident	111 Å²	111	98.9 Å²	98.9	58%	0.581	53%	0.529	S	S	*	.	H	α-helix	trans	-67.6	-19.7	-178.9	-69.8	172.4	0	0	0	113.7	L427 Q428 Q438	L427-L431 HydrophobicContact CD1-CG 4.48Å; L427-L431 HydrophobicContact CG-CD1 4.14Å; L427-L431 HydrophobicContact CG-CG 4.44Å; L427-L431 VanDerWaalsContact O-CG 3.27Å; L427-L431 WeakPolarHBondContact O-CG 3.36Å; L427-L431 PolarHBondContact O-N 3.06Å; Q428-L431 PolarHBondContact O-N 3.47Å; L431-Q438 PolarHBondContact O-NE2 3.4Å
432	V	82.4	Confident	81.5	Confident	129 Å²	129	100 Å²	100	78%	0.782	52%	0.518	S	S	*	.	H	α-helix	trans	-79.9	-19.1	174	174.3	0	0	0	0	112.3	Q428 Q429 L430	Q428-V432 WeakPolarHBondContact O-CG2 3.13Å; Q428-V432 PolarHBondContact O-N 2.87Å; Q429-V432 PolarHBondContact O-N 3.28Å; L430-V432 PolarHBondContact O-N 3.45Å
433	L	84.6	Confident	83	Confident	62 Å²	62	101.2 Å²	101.2	33%	0.325	52%	0.519	S	S	.	.	S	Bend	trans	-69.1	164	-179.4	-63	175	0	0	0	112.3	L430 Q437 Q438 I441	L430-L433 HydrophobicContact CD2-CD1 4.02Å; L430-L433 WeakPolarHBondContact O-CB 3.35Å; L430-L433 PolarHBondContact O-N 2.86Å; L430-L433 VanDerWaalsContact O-N 3.1Å; L433-Q437 HydrophobicContact CB-CB 4.1Å; L433-Q437 HydrophobicContact CD1-CB 4.44Å; L433-Q438 HydrophobicContact CB-CG 4.11Å; L433-Q438 PolarHBondContact O-NE2 3Å; L433-I441 HydrophobicContact CD1-CD1 3.53Å
434	Q	90.8	Very high	84.3	Confident	133 Å²	133	100.2 Å²	100.2	62%	0.621	51%	0.512	S	S	*	.			trans	-64.2	148.3	173.7	-67.4	-166.3	-4.2	0	0	111.3	E436 Q437 Q438	Q434-E436 PolarHBondContact O-N 2.93Å; Q434-E436 VanDerWaalsContact O-N 3.09Å; Q434-Q437 HydrophobicContact CB-CG 4.44Å; Q434-Q437 WeakPolarHBondContact O-CB 3.45Å; Q434-Q437 PolarHBondContact O-N 3.46Å; Q434-Q438 WeakPolarHBondContact O-CG 3.41Å; Q434-Q438 PolarHBondContact O-N 3.3Å
435	P	91.5	Very high	85.9	Confident	102 Å²	102	101.2 Å²	101.2	66%	0.662	51%	0.51	S	S	*	.	H	α-helix	trans	-52.9	-36	-177.2	-28.5	35.2	0	0	0	114.3	Q438 L439	P435-Q438 PolarHBondContact O-N 2.78Å; P435-L439 WeakPolarHBondContact O-CB 3.28Å; P435-L439 PolarHBondContact O-N 3.39Å
436	E	92.6	Very high	87.3	Confident	157 Å²	157	99.7 Å²	99.7	73%	0.734	50%	0.504	S	S	*	.	H	α-helix	trans	-64.5	-41.7	176.9	-62.3	-176	178.8	0	0	112.5	Q434 L439 N440	Q434-E436 PolarHBondContact O-N 2.93Å; Q434-E436 VanDerWaalsContact O-N 3.09Å; E436-L439 PolarHBondContact O-N 3.06Å; E436-N440 WeakPolarHBondContact O-CB 3.34Å; E436-N440 PolarHBondContact O-N 3.28Å
437	Q	91	Very high	88.2	Confident	96 Å²	96	100.1 Å²	100.1	45%	0.449	51%	0.506	S	S	.	.	H	α-helix	trans	-68.3	-41.4	177.3	-63.7	178.5	-47.8	0	0	110.9	L433 Q434 L439 N440 I441	L433-Q437 HydrophobicContact CB-CB 4.1Å; L433-Q437 HydrophobicContact CD1-CB 4.44Å; Q434-Q437 HydrophobicContact CB-CG 4.44Å; Q434-Q437 WeakPolarHBondContact O-CB 3.45Å; Q434-Q437 PolarHBondContact O-N 3.46Å; Q437-L439 VanDerWaalsContact C-N 3.34Å; Q437-L439 PolarHBondContact O-N 3.41Å; Q437-N440 PolarHBondContact O-N 3.48Å; Q437-I441 VanDerWaalsContact O-CG1 3.3Å; Q437-I441 WeakPolarHBondContact O-CG1 3.49Å; Q437-I441 PolarHBondContact O-N 3Å
438	Q	91.6	Very high	88.9	Confident	63 Å²	63	100.5 Å²	100.5	29%	0.294	51%	0.505	S	S	.	.	H	α-helix	trans	-57.8	-47.6	174.1	-64.6	-177.3	14.4	0	0	111.2	L430 L431 L433 Q434 P435 N440 I441 Y442	L430-Q438 VanDerWaalsContact O-CG 3.3Å; L430-Q438 WeakPolarHBondContact O-CG 3.41Å; L430-Q438 PolarHBondContact O-NE2 3.01Å; L431-Q438 PolarHBondContact O-NE2 3.4Å; L433-Q438 HydrophobicContact CB-CG 4.11Å; L433-Q438 PolarHBondContact O-NE2 3Å; Q434-Q438 WeakPolarHBondContact O-CG 3.41Å; Q434-Q438 PolarHBondContact O-N 3.3Å; P435-Q438 PolarHBondContact O-N 2.78Å; Q438-N440 VanDerWaalsContact C-N 3.34Å; Q438-N440 PolarHBondContact O-N 2.84Å; Q438-I441 PolarHBondContact O-N 3.44Å; Q438-Y442 WeakPolarHBondContact O-CB 3.46Å; Q438-Y442 PolarHBondContact O-N 3.49Å
439	L	92.4	Very high	90	Very high	95 Å²	95	96.6 Å²	96.6	50%	0.497	49%	0.488	S	S	.	.	H	α-helix	trans	-64.2	-39.3	-179.9	-158.6	91	0	0	0	111.8	P435 E436 Q437 K443	P435-L439 WeakPolarHBondContact O-CB 3.28Å; P435-L439 PolarHBondContact O-N 3.39Å; E436-L439 PolarHBondContact O-N 3.06Å; Q437-L439 VanDerWaalsContact C-N 3.34Å; Q437-L439 PolarHBondContact O-N 3.41Å; L439-K443 VanDerWaalsContact O-CG 3.29Å; L439-K443 WeakPolarHBondContact O-CG 3.34Å; L439-K443 PolarHBondContact O-N 3.14Å
440	N	94.4	Very high	90.8	Very high	103 Å²	103	93.5 Å²	93.5	55%	0.551	48%	0.475	S	S	*	.	H	α-helix	trans	-63.7	-49.5	176.7	-167.8	18.5	0	0	0	111	E436 Q437 Q438 Y442 K443 T444	E436-N440 WeakPolarHBondContact O-CB 3.34Å; E436-N440 PolarHBondContact O-N 3.28Å; Q437-N440 PolarHBondContact O-N 3.48Å; Q438-N440 VanDerWaalsContact C-N 3.34Å; Q438-N440 PolarHBondContact O-N 2.84Å; N440-Y442 VanDerWaalsContact C-N 3.32Å; N440-Y442 PolarHBondContact O-N 2.96Å; N440-K443 PolarHBondContact O-N 3.12Å; N440-K443 VanDerWaalsContact O-N 3.13Å; N440-T444 PolarHBondContact O-N 3.44Å; N440-T444 PolarHBondContact O-OG1 3.15Å
441	I	93.6	Very high	91.2	Very high	65 Å²	65	97.6 Å²	97.6	33%	0.333	49%	0.493	S	S	.	.	H	α-helix	trans	-60.3	-43	178.2	-66.7	168.9	0	0	0	111	L430 L433 Q437 Q438 K443 T444 L445	L430-I441 HydrophobicContact CD1-CG2 4.41Å; L430-I441 HydrophobicContact CD2-CB 4.39Å; L430-I441 HydrophobicContact CD2-CD1 3.41Å; L430-I441 VanDerWaalsContact CD2-CD1 3.41Å; L430-I441 HydrophobicContact CD2-CG1 4.43Å; L430-I441 HydrophobicContact CD2-CG2 3.8Å; L433-I441 HydrophobicContact CD1-CD1 3.53Å; Q437-I441 VanDerWaalsContact O-CG1 3.3Å; Q437-I441 WeakPolarHBondContact O-CG1 3.49Å; Q437-I441 PolarHBondContact O-N 3Å; Q438-I441 PolarHBondContact O-N 3.44Å; I441-K443 PolarHBondContact O-N 2.99Å; I441-T444 PolarHBondContact O-N 3.2Å; I441-L445 VanDerWaalsContact O-CB 3.29Å; I441-L445 WeakPolarHBondContact O-CB 3.31Å; I441-L445 PolarHBondContact O-N 2.89Å
442	Y	92.9	Very high	91.6	Very high	141 Å²	141	99.9 Å²	99.9	55%	0.553	50%	0.498	S	S	*	.	H	α-helix	trans	-58.6	-46	174.7	171.6	-99.9	0	0	0	112.2	Q438 N440 L445 K446	Q438-Y442 WeakPolarHBondContact O-CB 3.46Å; Q438-Y442 PolarHBondContact O-N 3.49Å; N440-Y442 VanDerWaalsContact C-N 3.32Å; N440-Y442 PolarHBondContact O-N 2.96Å; Y442-L445 PolarHBondContact O-N 2.87Å; Y442-K446 HydrophobicContact CE1-CD 4.22Å; Y442-K446 VanDerWaalsContact O-CB 3.23Å; Y442-K446 WeakPolarHBondContact O-CB 3.37Å; Y442-K446 PolarHBondContact O-N 3.33Å
443	K	93.8	Very high	91.9	Very high	117 Å²	117	96.9 Å²	96.9	51%	0.509	49%	0.493	S	S	.	.	H	α-helix	trans	-62.8	-46.8	178.1	-74.3	172.5	-177.8	178	0	111.5	L439 N440 I441 K446 T447	L439-K443 VanDerWaalsContact O-CG 3.29Å; L439-K443 WeakPolarHBondContact O-CG 3.34Å; L439-K443 PolarHBondContact O-N 3.14Å; N440-K443 PolarHBondContact O-N 3.12Å; N440-K443 VanDerWaalsContact O-N 3.13Å; I441-K443 PolarHBondContact O-N 2.99Å; K443-K446 PolarHBondContact O-N 3.48Å; K443-T447 PolarHBondContact O-N 3.26Å; K443-T447 PolarHBondContact O-OG1 3.44Å; K443-T447 VanDerWaalsContact O-OG1 3.05Å
444	T	93.4	Very high	92.1	Very high	80 Å²	80	99.6 Å²	99.6	49%	0.491	51%	0.507	S	S	.	.	H	α-helix	trans	-60.7	-46.8	177.3	-56.3	0	0	0	0	111.5	N440 I441 K446 T447 H448	N440-T444 PolarHBondContact O-N 3.44Å; N440-T444 PolarHBondContact O-OG1 3.15Å; I441-T444 PolarHBondContact O-N 3.2Å; T444-K446 PolarHBondContact O-N 3.26Å; T444-T447 PolarHBondContact O-N 3.4Å; T444-H448 PolarHBondContact O-N 2.65Å
445	L	92.8	Very high	92	Very high	97 Å²	97	96.9 Å²	96.9	51%	0.508	50%	0.496	S	S	.	.	H	α-helix	trans	-61.6	-45.3	177.7	-177.6	63.8	0	0	0	111	I441 Y442 T447 H448 L449	I441-L445 VanDerWaalsContact O-CB 3.29Å; I441-L445 WeakPolarHBondContact O-CB 3.31Å; I441-L445 PolarHBondContact O-N 2.89Å; Y442-L445 PolarHBondContact O-N 2.87Å; L445-T447 PolarHBondContact O-N 2.89Å; L445-H448 PolarHBondContact O-N 3.01Å; L445-L449 HydrophobicContact CD1-CD1 4.36Å; L445-L449 HydrophobicContact CD1-CG 4.36Å; L445-L449 HydrophobicContact CG-CD1 4.01Å; L445-L449 HydrophobicContact CG-CG 4.41Å; L445-L449 VanDerWaalsContact O-CG 3.26Å; L445-L449 WeakPolarHBondContact O-CG 3.24Å; L445-L449 PolarHBondContact O-N 3.38Å
446	K	91.8	Very high	91.5	Very high	75 Å²	75	99.8 Å²	99.8	33%	0.326	50%	0.501	S	S	.	.	H	α-helix	trans	-57.7	-47.7	176.4	-179.6	178.7	179	176.1	0	111.6	Y442 K443 T444 H448 L449 I450 L455	Y442-K446 HydrophobicContact CE1-CD 4.22Å; Y442-K446 VanDerWaalsContact O-CB 3.23Å; Y442-K446 WeakPolarHBondContact O-CB 3.37Å; Y442-K446 PolarHBondContact O-N 3.33Å; K443-K446 PolarHBondContact O-N 3.48Å; T444-K446 PolarHBondContact O-N 3.26Å; K446-H448 PolarHBondContact O-N 3.01Å; K446-L449 PolarHBondContact O-N 3.42Å; K446-I450 HydrophobicContact CG-CD1 3.98Å; K446-I450 VanDerWaalsContact O-CG1 3.32Å; K446-I450 WeakPolarHBondContact O-CG1 3.25Å; K446-I450 PolarHBondContact O-N 2.9Å; K446-L455 HydrophobicContact CG-CD2 4.46Å
447	T	93.4	Very high	90.8	Very high	73 Å²	73	96.8 Å²	96.8	45%	0.448	50%	0.495	S	S	.	.	H	α-helix	trans	-58.9	-47.4	177.6	-58.6	0	0	0	0	111.1	K443 T444 L445 L449 I450 E451	K443-T447 PolarHBondContact O-N 3.26Å; K443-T447 PolarHBondContact O-OG1 3.44Å; K443-T447 VanDerWaalsContact O-OG1 3.05Å; T444-T447 PolarHBondContact O-N 3.4Å; L445-T447 PolarHBondContact O-N 2.89Å; T447-L449 VanDerWaalsContact C-N 3.34Å; T447-L449 PolarHBondContact O-N 3.19Å; T447-I450 PolarHBondContact O-N 3.32Å; T447-E451 HydrophobicContact CG2-CG 4.46Å; T447-E451 WeakPolarHBondContact O-CG 3.46Å; T447-E451 PolarHBondContact O-N 3.5Å
448	H	93.1	Very high	89.7	Confident	107 Å²	107	96 Å²	96	50%	0.495	51%	0.505	S	S	.	.	H	α-helix	trans	-62.4	-38	177.2	-103.5	9.6	0	0	0	113.7	T444 L445 K446 I450 E451 K452	T444-H448 PolarHBondContact O-N 2.65Å; L445-H448 PolarHBondContact O-N 3.01Å; K446-H448 PolarHBondContact O-N 3.01Å; H448-I450 VanDerWaalsContact C-N 3.32Å; H448-E451 IonicContact CE1-OE2 3.65Å; H448-E451 IonicContact CG-OE2 4Å; H448-E451 IonicContact ND1-OE2 2.9Å; H448-E451 PolarHBondContact ND1-OE2 3.39Å; H448-E451 PolarHBondContact O-N 3.18Å; H448-K452 WeakPolarHBondContact O-CB 3.41Å; H448-K452 WeakPolarHBondContact O-CG 3.22Å; H448-K452 PolarHBondContact O-N 3.01Å
449	L	92.5	Very high	88.1	Confident	51 Å²	51	100.2 Å²	100.2	27%	0.267	53%	0.529	S	S	.	.	H	α-helix	trans	-68.6	-32.7	176.9	-68.9	173.2	0	0	0	111.9	L445 K446 T447 G453 I454 L455	L445-L449 HydrophobicContact CD1-CD1 4.36Å; L445-L449 HydrophobicContact CD1-CG 4.36Å; L445-L449 HydrophobicContact CG-CD1 4.01Å; L445-L449 HydrophobicContact CG-CG 4.41Å; L445-L449 VanDerWaalsContact O-CG 3.26Å; L445-L449 WeakPolarHBondContact O-CG 3.24Å; L445-L449 PolarHBondContact O-N 3.38Å; K446-L449 PolarHBondContact O-N 3.42Å; T447-L449 VanDerWaalsContact C-N 3.34Å; T447-L449 PolarHBondContact O-N 3.19Å; L449-G453 PolarHBondContact O-N 2.9Å; L449-I454 HydrophobicContact CD2-CB 4.31Å; L449-I454 HydrophobicContact CD2-CD1 3.94Å; L449-I454 HydrophobicContact CD2-CG2 4.36Å; L449-I454 PolarHBondContact O-N 2.89Å; L449-L455 HydrophobicContact CB-CB 4.02Å; L449-L455 HydrophobicContact CD1-CD1 4.42Å; L449-L455 PolarHBondContact O-N 3.35Å; L449-L455 VanDerWaalsContact O-N 3.08Å
450	I	92.2	Very high	86.3	Confident	57 Å²	57	105.7 Å²	105.7	29%	0.292	55%	0.549	S	S	.	.	H	α-helix	trans	-70.4	-45.9	172.9	-66.9	167.9	0	0	0	110.6	K446 T447 H448 K452 G453 L455 P457	K446-I450 HydrophobicContact CG-CD1 3.98Å; K446-I450 VanDerWaalsContact O-CG1 3.32Å; K446-I450 WeakPolarHBondContact O-CG1 3.25Å; K446-I450 PolarHBondContact O-N 2.9Å; T447-I450 PolarHBondContact O-N 3.32Å; H448-I450 VanDerWaalsContact C-N 3.32Å; I450-K452 VanDerWaalsContact C-N 3.27Å; I450-K452 PolarHBondContact O-N 3.19Å; I450-G453 PolarHBondContact O-N 3.23Å; I450-L455 HydrophobicContact CG1-CB 4.06Å; I450-L455 HydrophobicContact CG1-CD2 4.28Å; I450-P457 HydrophobicContact CG2-CB 4.47Å
451	E	92.3	Very high	83.8	Confident	135 Å²	135	110.4 Å²	110.4	63%	0.631	58%	0.581	S	S	*	*	H	α-helix	trans	-59.7	-36.9	177	-73.6	170.9	166.3	0	0	112.4	T447 H448 G453	T447-E451 HydrophobicContact CG2-CG 4.46Å; T447-E451 WeakPolarHBondContact O-CG 3.46Å; T447-E451 PolarHBondContact O-N 3.5Å; H448-E451 IonicContact CE1-OE2 3.65Å; H448-E451 IonicContact CG-OE2 4Å; H448-E451 IonicContact ND1-OE2 2.9Å; H448-E451 PolarHBondContact ND1-OE2 3.39Å; H448-E451 PolarHBondContact O-N 3.18Å; E451-G453 PolarHBondContact O-N 3.44Å
452	K	90.6	Very high	83.4	Confident	159 Å²	159	112.7 Å²	112.7	69%	0.691	59%	0.593	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.7	-2.2	174.4	-73.5	-171.3	173.9	-173.9	0	114.1	H448 I450 I454	H448-K452 WeakPolarHBondContact O-CB 3.41Å; H448-K452 WeakPolarHBondContact O-CG 3.22Å; H448-K452 PolarHBondContact O-N 3.01Å; I450-K452 VanDerWaalsContact C-N 3.27Å; I450-K452 PolarHBondContact O-N 3.19Å; K452-I454 HydrophobicContact CB-CD1 3.92Å; K452-I454 HydrophobicContact CB-CG1 3.94Å; K452-I454 HydrophobicContact CD-CD1 4.26Å; K452-I454 PolarHBondContact O-N 3.12Å
453	G	88.1	Confident	82.9	Confident	66 Å²	66	111.2 Å²	111.2	68%	0.68	60%	0.596	S	S	*	*	T	Hydrogen-bonded Turn	trans	68.6	15.2	-178.7	0	0	0	0	0	114.5	L449 I450 E451	L449-G453 PolarHBondContact O-N 2.9Å; I450-G453 PolarHBondContact O-N 3.23Å; E451-G453 PolarHBondContact O-N 3.44Å
454	I	90.4	Very high	82.2	Confident	120 Å²	120	110.9 Å²	110.9	62%	0.615	60%	0.6	S	S	*	*	S	Bend	trans	-80.4	-36	178.8	-56.5	173.5	0	0	0	109.9	L449 K452	L449-I454 HydrophobicContact CD2-CB 4.31Å; L449-I454 HydrophobicContact CD2-CD1 3.94Å; L449-I454 HydrophobicContact CD2-CG2 4.36Å; L449-I454 PolarHBondContact O-N 2.89Å; K452-I454 HydrophobicContact CB-CD1 3.92Å; K452-I454 HydrophobicContact CB-CG1 3.94Å; K452-I454 HydrophobicContact CD-CD1 4.26Å; K452-I454 PolarHBondContact O-N 3.12Å
455	L	87.3	Confident	81.6	Confident	75 Å²	75	112.7 Å²	112.7	39%	0.393	61%	0.607	S	S	.	*	S	Bend	trans	-111.1	131.6	177.2	-142.8	110.1	0	0	0	109.8	K446 L449 I450	K446-L455 HydrophobicContact CG-CD2 4.46Å; L449-L455 HydrophobicContact CB-CB 4.02Å; L449-L455 HydrophobicContact CD1-CD1 4.42Å; L449-L455 PolarHBondContact O-N 3.35Å; L449-L455 VanDerWaalsContact O-N 3.08Å; I450-L455 HydrophobicContact CG1-CB 4.06Å; I450-L455 HydrophobicContact CG1-CD2 4.28Å
456	Q	82.3	Confident	80.9	Confident	164 Å²	164	113.7 Å²	113.7	77%	0.766	61%	0.613	S	S	*	*	P	Polyproline II helix	trans	-71.4	139.3	173.7	-66.3	-173.9	1.6	0	0	110.2	A458	Q456-A458 PolarHBondContact O-N 2.89Å
457	P	76.1	Confident	80.2	Confident	93 Å²	93	116.3 Å²	116.3	60%	0.604	63%	0.632	S	S	*	*	P	Polyproline II helix	trans	-60.4	136.9	171.5	24.7	-30.7	0	0	0	108.8	I450 L459	I450-P457 HydrophobicContact CG2-CB 4.47Å; P457-L459 PolarHBondContact O-N 3.42Å
458	A	69.4	Low	79.2	Confident	81 Å²	81	119.4 Å²	119.4	67%	0.669	65%	0.645	S	S	*	*	P	Polyproline II helix	trans	-56.5	119.8	178.9	0	0	0	0	0	109.2	Q456 K460	Q456-A458 PolarHBondContact O-N 2.89Å; A458-K460 PolarHBondContact O-N 3.37Å
459	L	57.7	Low	78.1	Confident	151 Å²	151	120.3 Å²	120.3	79%	0.791	66%	0.657	S	S	*	*			trans	-54.8	113.3	169.5	-98.4	133.4	0	0	0	107.4	P457 V461	P457-L459 PolarHBondContact O-N 3.42Å; L459-V461 PolarHBondContact O-N 3.47Å
460	K	54.3	Low	77	Confident	209 Å²	209	126.1 Å²	126.1	91%	0.909	69%	0.689	S	S	*	*			trans	-66.7	101.4	166	-72.7	-177.4	177.1	-179.4	0	106.3	A458	A458-K460 PolarHBondContact O-N 3.37Å
461	V	43	Very low	75.6	Confident	203 Å²	203	132.4 Å²	132.4	100%	1.23	73%	0.725	S	S	*	*			trans	-88.6	0	164.5	-179.6	0	0	0	0	108.2	L459	L459-V461 PolarHBondContact O-N 3.47Å

Retrieved 461 of 461 residues in 888.4 ms (Link to these results)

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