A0A096N6I1_PAPAN Loading...

Cullin-5

AlphaFold DB (Q93034), UniProt , Accession A0A096N6I1, Species PAPAN (Papio anubis, Olive baboon), Gene CUL5, Length 780 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M43.3Very low45.1Very low219 Ų219120.6 Ų120.6100%1.07967%0.671SS**  0-18.50-69-172.9-158.300114.2
2A44.2Very low46.4Very low82 Ų82117.8 Ų117.868%0.67867%0.665SS**  trans-80.5-19.2177.800000115.5
3T43.2Very low48.3Very low118 Ų118111.8 Ų111.872%0.72463%0.631SS**THydrogen-bonded Turntrans-79.4-14.6-178.834.20000114.5
4S43.3Very low50.4Low76 Ų76111.2 Ų111.253%0.53162%0.62SS.*THydrogen-bonded Turntrans-85.2-14.6179.5-170.80000114.1
5N43.1Very low52.8Low111 Ų111105.3 Ų105.359%0.59459%0.585SS**THydrogen-bonded Turntrans-93.7-19.2-178.1-79.8-15.1000113.9L7 K8N5-L7 VanDerWaalsContact C-N 3.3Å; N5-L7 PolarHBondContact O-N 3Å; N5-K8 PolarHBondContact O-N 2.68Å
6L41.5Very low54.8Low133 Ų133104.3 Ų104.370%0.69657%0.574SS**THydrogen-bonded Turntrans-76-17.3175.9-79.9154.2000113.3
7L44.5Very low56.5Low123 Ų123103.4 Ų103.464%0.64457%0.569SS**THydrogen-bonded Turntrans-82.1-12.7174-81153.3000113.3N5N5-L7 VanDerWaalsContact C-N 3.3Å; N5-L7 PolarHBondContact O-N 3Å
8K43.6Very low58.2Low156 Ų156100.8 Ų100.868%0.67855%0.551SS**THydrogen-bonded Turntrans-85.7-7.3-174.2-78-174.7174.6179.80115.5N5N5-K8 PolarHBondContact O-N 2.68Å
9N50Low59.9Low110 Ų11096.6 Ų96.659%0.58853%0.526SS*.THydrogen-bonded Turntrans-108.18.7175.9-82.9-1.5000114.2G11 S12N9-G11 VanDerWaalsContact C-N 3.34Å; N9-G11 PolarHBondContact O-N 3.48Å; N9-S12 PolarHBondContact O-N 3.39Å
10K45.3Very low61.2Low148 Ų14897.8 Ų97.864%0.64353%0.532SS*.THydrogen-bonded Turntrans-6597.2166.2-95.1-172.2166.5-167.60108.4W53K10-W53 HydrophobicContact CG-CE3 4.29Å; K10-W53 HydrophobicContact CG-CZ3 4.23Å
11G53.6Low62.6Low51 Ų5199.9 Ų99.953%0.52654%0.536SS..THydrogen-bonded Turntrans132.8-1.5175.900000117N9N9-G11 VanDerWaalsContact C-N 3.34Å; N9-G11 PolarHBondContact O-N 3.48Å
12S61.5Low64.9Low86 Ų8689.4 Ų89.460%0.60149%0.485SS*.SBendtrans-90.4-18.2-17877.20000115.4N9N9-S12 PolarHBondContact O-N 3.39Å
13L70.4Confident67.1Low41 Ų4190.9 Ų90.922%0.21547%0.473CS..  trans-104.2112.7-179.4-171.6132.4000108.3K18 A49 V50 W53L13-K18 HydrophobicContact CD1-CG 4.47Å; L13-K18 HydrophobicContact CD2-CG 4.31Å; L13-K18 HydrophobicContact CG-CG 4.46Å; L13-A49 HydrophobicContact CD2-CB 4.39Å; L13-V50 HydrophobicContact CD2-CG2 3.94Å; L13-W53 HydrophobicContact CB-CB 4.3Å; L13-W53 HydrophobicContact CD2-CB 4.42Å
14Q78.8Confident69.5Low103 Ų10388.4 Ų88.448%0.48146%0.459SS..  trans-101.9151.7177.4-59.8-162.75.200110.6E16 D17Q14-E16 PolarHBondContact O-N 3.47Å; Q14-D17 PolarHBondContact N-OD2 2.9Å; Q14-D17 WeakPolarHBondContact O-CB 3.22Å; Q14-D17 PolarHBondContact O-N 2.9Å
15F86.2Confident71.8Confident23 Ų2385.4 Ų85.410%0.10144%0.437CS..Hα-helixtrans-45.2-43.7171.6164.3-97.4000112.8D17 K18 W19 V50 D54 K60 I61 A64F15-D17 PolarHBondContact O-N 3.15Å; F15-K18 PolarHBondContact O-N 3.06Å; F15-K18 VanDerWaalsContact O-N 3.13Å; F15-W19 HydrophobicContact CD1-CB 4.38Å; F15-W19 HydrophobicContact CD2-CB 4.16Å; F15-W19 HydrophobicContact CE1-CB 3.93Å; F15-W19 HydrophobicContact CE1-CG 4.01Å; F15-W19 HydrophobicContact CE2-CB 3.69Å; F15-W19 AromaticContact CE2-CD2 3.58Å; F15-W19 HydrophobicContact CE2-CD2 3.58Å; F15-W19 AromaticContact CE2-CE3 3.6Å; F15-W19 HydrophobicContact CE2-CE3 3.6Å; F15-W19 AromaticContact CE2-CG 3.63Å; F15-W19 HydrophobicContact CE2-CG 3.63Å; F15-W19 HydrophobicContact CE2-CZ3 4.46Å; F15-W19 HydrophobicContact CG-CB 4.5Å; F15-W19 HydrophobicContact CZ-CB 3.57Å; F15-W19 AromaticContact CZ-CD1 3.7Å; F15-W19 AromaticContact CZ-CD2 3.57Å; F15-W19 HydrophobicContact CZ-CD2 3.57Å; F15-W19 HydrophobicContact CZ-CE3 4.09Å; F15-W19 AromaticContact CZ-CG 3.3Å; F15-W19 HydrophobicContact CZ-CG 3.3Å; F15-W19 WeakPolarHBondContact O-CB 3.49Å; F15-W19 PolarHBondContact O-N 3.04Å; F15-V50 HydrophobicContact CB-CG1 4.33Å; F15-V50 HydrophobicContact CD2-CG1 4.43Å; F15-D54 WeakPolarHBondContact CB-OD2 3.32Å; F15-D54 PolarHBondContact N-OD2 3.27Å; F15-K60 HydrophobicContact CB-CB 4.31Å; F15-K60 HydrophobicContact CB-CD 3.68Å; F15-K60 HydrophobicContact CD1-CB 3.89Å; F15-K60 HydrophobicContact CD1-CD 3.61Å; F15-K60 HydrophobicContact CD1-CG 4.36Å; F15-K60 HydrophobicContact CD2-CB 3.75Å; F15-K60 HydrophobicContact CE1-CB 4.09Å; F15-K60 HydrophobicContact CE1-CD 4.39Å; F15-K60 HydrophobicContact CE2-CB 3.95Å; F15-K60 HydrophobicContact CG-CB 3.7Å; F15-K60 HydrophobicContact CG-CD 3.7Å; F15-K60 HydrophobicContact CG-CG 4.4Å; F15-K60 HydrophobicContact CZ-CB 4.12Å; F15-I61 HydrophobicContact CD2-CG1 3.78Å; F15-I61 HydrophobicContact CE2-CB 4.48Å; F15-I61 HydrophobicContact CE2-CG1 3.81Å; F15-A64 HydrophobicContact CZ-CB 3.98Å
16E85.1Confident74.1Confident88 Ų8880.1 Ų80.141%0.41141%0.409SS..Hα-helixtrans-57.7-34.5-178.5-70.875.8-172.600112.5Q14 K18 K60Q14-E16 PolarHBondContact O-N 3.47Å; E16-K18 VanDerWaalsContact C-N 3.26Å; E16-K18 PolarHBondContact O-N 3.14Å; E16-K60 VanDerWaalsContact CD-NZ 3.26Å; E16-K60 IonicContact OE1-NZ 2.68Å; E16-K60 PolarHBondContact OE1-NZ 3.01Å; E16-K60 IonicContact OE2-NZ 3Å; E16-K60 PolarHBondContact OE2-NZ 3.01Å
17D82.5Confident76.5Confident89 Ų8975.8 Ų75.848%0.47639%0.386SS..Hα-helixtrans-72.4-20.2-178.2-56.7-44.6000113.2Q14 F15 F21Q14-D17 PolarHBondContact N-OD2 2.9Å; Q14-D17 WeakPolarHBondContact O-CB 3.22Å; Q14-D17 PolarHBondContact O-N 2.9Å; F15-D17 PolarHBondContact O-N 3.15Å; D17-F21 WeakPolarHBondContact O-CD2 3.48Å; D17-F21 WeakPolarHBondContact O-CE2 3.45Å
18K87.5Confident78.8Confident57 Ų5772.8 Ų72.825%0.24837%0.367CS..Hα-helixtrans-116.1-30.2-172.1-67.8-62.4-164.3158.80113.5L13 F15 E16 D20 F21 M22 D46 V50L13-K18 HydrophobicContact CD1-CG 4.47Å; L13-K18 HydrophobicContact CD2-CG 4.31Å; L13-K18 HydrophobicContact CG-CG 4.46Å; F15-K18 PolarHBondContact O-N 3.06Å; F15-K18 VanDerWaalsContact O-N 3.13Å; E16-K18 VanDerWaalsContact C-N 3.26Å; E16-K18 PolarHBondContact O-N 3.14Å; K18-D20 VanDerWaalsContact C-N 3.3Å; K18-D20 PolarHBondContact O-N 3.11Å; K18-F21 PolarHBondContact O-N 3.19Å; K18-F21 VanDerWaalsContact O-N 3.1Å; K18-M22 HydrophobicContact CB-CE 3.71Å; K18-M22 WeakPolarHBondContact O-CG 3.48Å; K18-M22 PolarHBondContact O-N 2.91Å; K18-D46 WeakPolarHBondContact CE-OD1 3.19Å; K18-D46 IonicContact NZ-OD1 3.52Å; K18-D46 PolarHBondContact NZ-OD1 2.99Å; K18-D46 IonicContact NZ-OD2 3.25Å; K18-V50 HydrophobicContact CB-CG2 3.77Å; K18-V50 HydrophobicContact CG-CG2 4.03Å
19W89.9Confident81Confident21 Ų2165.9 Ų65.98%0.0834%0.338CS..Hα-helixtrans-62.4-35.7-177.3-170.7-110.5000113.3F15 F21 M22 R23 I61 A64 L65F15-W19 HydrophobicContact CD1-CB 4.38Å; F15-W19 HydrophobicContact CD2-CB 4.16Å; F15-W19 HydrophobicContact CE1-CB 3.93Å; F15-W19 HydrophobicContact CE1-CG 4.01Å; F15-W19 HydrophobicContact CE2-CB 3.69Å; F15-W19 AromaticContact CE2-CD2 3.58Å; F15-W19 HydrophobicContact CE2-CD2 3.58Å; F15-W19 AromaticContact CE2-CE3 3.6Å; F15-W19 HydrophobicContact CE2-CE3 3.6Å; F15-W19 AromaticContact CE2-CG 3.63Å; F15-W19 HydrophobicContact CE2-CG 3.63Å; F15-W19 HydrophobicContact CE2-CZ3 4.46Å; F15-W19 HydrophobicContact CG-CB 4.5Å; F15-W19 HydrophobicContact CZ-CB 3.57Å; F15-W19 AromaticContact CZ-CD1 3.7Å; F15-W19 AromaticContact CZ-CD2 3.57Å; F15-W19 HydrophobicContact CZ-CD2 3.57Å; F15-W19 HydrophobicContact CZ-CE3 4.09Å; F15-W19 AromaticContact CZ-CG 3.3Å; F15-W19 HydrophobicContact CZ-CG 3.3Å; F15-W19 WeakPolarHBondContact O-CB 3.49Å; F15-W19 PolarHBondContact O-N 3.04Å; W19-F21 PolarHBondContact O-N 3.31Å; W19-M22 HydrophobicContact CE3-CB 4.16Å; W19-M22 HydrophobicContact CE3-CE 3.92Å; W19-M22 HydrophobicContact CE3-SD 4.5Å; W19-M22 HydrophobicContact CZ3-CB 4.49Å; W19-M22 PolarHBondContact O-N 2.9Å; W19-M22 VanDerWaalsContact O-N 3.15Å; W19-R23 HydrophobicContact CD2-CB 4.47Å; W19-R23 HydrophobicContact CZ2-CB 4.38Å; W19-R23 HydrophobicContact CZ2-CG 4.48Å; W19-R23 VanDerWaalsContact O-CB 3.23Å; W19-R23 WeakPolarHBondContact O-CB 3.34Å; W19-R23 PolarHBondContact O-N 3.12Å; W19-I61 HydrophobicContact CZ3-CG2 4.16Å; W19-A64 HydrophobicContact CD2-CB 4.24Å; W19-A64 VanDerWaalsContact CE2-CB 3.47Å; W19-A64 HydrophobicContact CH2-CB 3.93Å; W19-A64 HydrophobicContact CZ2-CB 3.31Å; W19-L65 HydrophobicContact CH2-CD2 3.98Å; W19-L65 HydrophobicContact CH2-CG 4.04Å
20D87.5Confident82.8Confident121 Ų12160.8 Ų60.865%0.64731%0.311SS*.Hα-helixtrans-61.9-26.6176.8-74-17.8000113K18 P24K18-D20 VanDerWaalsContact C-N 3.3Å; K18-D20 PolarHBondContact O-N 3.11Å; D20-P24 WeakPolarHBondContact O-CD 3.34Å; D20-P24 WeakPolarHBondContact O-CG 3.37Å
21F88.9Confident84.9Confident141 Ų14159.6 Ų59.662%0.61830%0.302SS*.Hα-helixtrans-87.8-35.9174.1-59.5-78.5000112.6D17 K18 W19D17-F21 WeakPolarHBondContact O-CD2 3.48Å; D17-F21 WeakPolarHBondContact O-CE2 3.45Å; K18-F21 PolarHBondContact O-N 3.19Å; K18-F21 VanDerWaalsContact O-N 3.1Å; W19-F21 PolarHBondContact O-N 3.31Å
22M91.3Very high86.4Confident0 Ų061.3 Ų61.30%030%0.297CS..Hα-helixtrans-71.6-43.6178.9-69.1-170.7-85.100112.5K18 W19 I25 V26 L43 D46 V47 V50K18-M22 HydrophobicContact CB-CE 3.71Å; K18-M22 WeakPolarHBondContact O-CG 3.48Å; K18-M22 PolarHBondContact O-N 2.91Å; W19-M22 HydrophobicContact CE3-CB 4.16Å; W19-M22 HydrophobicContact CE3-CE 3.92Å; W19-M22 HydrophobicContact CE3-SD 4.5Å; W19-M22 HydrophobicContact CZ3-CB 4.49Å; W19-M22 PolarHBondContact O-N 2.9Å; W19-M22 VanDerWaalsContact O-N 3.15Å; M22-I25 WeakPolarHBondContact O-CB 3.43Å; M22-I25 PolarHBondContact O-N 3.27Å; M22-V26 PolarHBondContact O-N 3.33Å; M22-L43 HydrophobicContact CB-CD1 3.85Å; M22-L43 HydrophobicContact CG-CD1 3.88Å; M22-L43 HydrophobicContact SD-CD1 4.23Å; M22-D46 HydrophobicContact CE-CB 4.48Å; M22-D46 HydrophobicContact CG-CB 3.8Å; M22-D46 HydrophobicContact SD-CB 3.76Å; M22-V47 HydrophobicContact SD-CG2 3.67Å; M22-V50 HydrophobicContact CE-CG2 3.88Å
23R92.3Very high87.8Confident112 Ų11261.5 Ų61.542%0.42329%0.288SS..Hα-helixtrans-57.2-45.4-171.8-176.1-178.3-172.2-147-0.5113.7W19 I25 V26 L27 D68W19-R23 HydrophobicContact CD2-CB 4.47Å; W19-R23 HydrophobicContact CZ2-CB 4.38Å; W19-R23 HydrophobicContact CZ2-CG 4.48Å; W19-R23 VanDerWaalsContact O-CB 3.23Å; W19-R23 WeakPolarHBondContact O-CB 3.34Å; W19-R23 PolarHBondContact O-N 3.12Å; R23-I25 PolarHBondContact O-N 3.47Å; R23-V26 PolarHBondContact O-N 3Å; R23-L27 HydrophobicContact CG-CD1 4.18Å; R23-L27 HydrophobicContact CG-CG 4.34Å; R23-L27 WeakPolarHBondContact O-CG 3.46Å; R23-L27 PolarHBondContact O-N 3.5Å; R23-D68 IonicContact CZ-OD1 2.83Å; R23-D68 IonicContact NE-OD1 3.24Å; R23-D68 PolarHBondContact NE-OD1 2.98Å; R23-D68 VanDerWaalsContact NE-OD1 3.15Å; R23-D68 IonicContact NE-OD2 3.24Å; R23-D68 PolarHBondContact NE-OD2 3.41Å; R23-D68 IonicContact NH2-OD1 2.62Å; R23-D68 PolarHBondContact NH2-OD1 3.24Å
24P92Very high88.6Confident67 Ų6764.7 Ų64.744%0.43531%0.314SS..Hα-helixtrans-58.8-34.3175.3-25.235.1000113.4D20 K28D20-P24 WeakPolarHBondContact O-CD 3.34Å; D20-P24 WeakPolarHBondContact O-CG 3.37Å; P24-K28 VanDerWaalsContact O-CG 3.29Å; P24-K28 WeakPolarHBondContact O-CG 3.26Å; P24-K28 PolarHBondContact O-N 3.3Å
25I92.7Very high89Confident12 Ų1261.7 Ų61.76%0.06230%0.302CS..Hα-helixtrans-71.9-44.4177.7-54.5168000109.5M22 R23 L27 K28 L29 V35 Q39 L43M22-I25 WeakPolarHBondContact O-CB 3.43Å; M22-I25 PolarHBondContact O-N 3.27Å; R23-I25 PolarHBondContact O-N 3.47Å; I25-L27 VanDerWaalsContact C-N 3.35Å; I25-L27 PolarHBondContact O-N 2.87Å; I25-K28 WeakPolarHBondContact O-CB 3.47Å; I25-K28 PolarHBondContact O-N 3.2Å; I25-L29 HydrophobicContact CG2-CD1 4.38Å; I25-L29 VanDerWaalsContact O-CG 3.31Å; I25-L29 WeakPolarHBondContact O-CG 3.4Å; I25-L29 PolarHBondContact O-N 2.91Å; I25-V35 HydrophobicContact CG2-CG1 3.79Å; I25-V35 HydrophobicContact CG2-CG2 4.39Å; I25-Q39 HydrophobicContact CD1-CB 3.92Å; I25-Q39 HydrophobicContact CD1-CG 4.16Å; I25-Q39 HydrophobicContact CG1-CB 4.16Å; I25-Q39 HydrophobicContact CG1-CG 4.28Å; I25-Q39 HydrophobicContact CG2-CB 4.34Å; I25-L43 HydrophobicContact CD1-CB 4.49Å; I25-L43 HydrophobicContact CG2-CB 4.34Å; I25-L43 HydrophobicContact CG2-CD2 3.93Å
26V91.7Very high89.3Confident1 Ų164.2 Ų64.21%0.00632%0.32CS..Hα-helixtrans-57.5-46.2174.5172.50000111.6M22 R23 K28 L29 L30 L43 L65 L107 F111M22-V26 PolarHBondContact O-N 3.33Å; R23-V26 PolarHBondContact O-N 3Å; V26-K28 PolarHBondContact O-N 3.11Å; V26-L29 WeakPolarHBondContact O-CB 3.36Å; V26-L29 PolarHBondContact O-N 3.33Å; V26-L30 HydrophobicContact CG1-CD1 4.19Å; V26-L30 PolarHBondContact O-N 2.87Å; V26-L43 HydrophobicContact CG2-CD1 4.16Å; V26-L43 HydrophobicContact CG2-CD2 4.5Å; V26-L65 HydrophobicContact CG1-CD2 3.89Å; V26-L65 HydrophobicContact CG2-CD2 4.44Å; V26-L107 HydrophobicContact CG1-CD1 4.23Å; V26-F111 HydrophobicContact CG2-CE2 4.41Å; V26-F111 HydrophobicContact CG2-CZ 3.85Å
27L91.9Very high89.6Confident41 Ų4169.4 Ų69.422%0.21534%0.341CS..Hα-helixtrans-63.7-39.3177.6-69176.1000112.2R23 I25 L29 L30 R31 D68R23-L27 HydrophobicContact CG-CD1 4.18Å; R23-L27 HydrophobicContact CG-CG 4.34Å; R23-L27 WeakPolarHBondContact O-CG 3.46Å; R23-L27 PolarHBondContact O-N 3.5Å; I25-L27 VanDerWaalsContact C-N 3.35Å; I25-L27 PolarHBondContact O-N 2.87Å; L27-L29 VanDerWaalsContact C-N 3.34Å; L27-L30 PolarHBondContact O-N 3.19Å; L27-R31 WeakPolarHBondContact O-CB 3.44Å; L27-R31 VanDerWaalsContact O-CG 3.28Å; L27-R31 WeakPolarHBondContact O-CG 3.38Å; L27-R31 PolarHBondContact O-N 2.99Å; L27-D68 HydrophobicContact CD2-CB 4.29Å
28K91.5Very high89.9Confident60 Ų6070.6 Ų70.626%0.26134%0.343SS..Hα-helixtrans-60.1-43.9173.3-79.5178.3173.5-169.10111.9P24 I25 V26 R31 Q32 E33 V35P24-K28 VanDerWaalsContact O-CG 3.29Å; P24-K28 WeakPolarHBondContact O-CG 3.26Å; P24-K28 PolarHBondContact O-N 3.3Å; I25-K28 WeakPolarHBondContact O-CB 3.47Å; I25-K28 PolarHBondContact O-N 3.2Å; V26-K28 PolarHBondContact O-N 3.11Å; K28-R31 CarbonylContact O-C 3.55Å; K28-R31 PolarHBondContact O-N 3.47Å; K28-Q32 PolarHBondContact O-N 2.9Å; K28-E33 HydrophobicContact CB-CB 3.99Å; K28-E33 HydrophobicContact CG-CB 3.99Å; K28-E33 WeakPolarHBondContact CG-OE2 3.41Å; K28-E33 PolarHBondContact O-N 3.46Å; K28-V35 HydrophobicContact CB-CG2 3.73Å; K28-V35 HydrophobicContact CD-CG2 4.36Å
29L90.8Very high90.2Very high12 Ų1270.2 Ų70.26%0.06334%0.343CS..Hα-helixtrans-62.7-50.9177.7-65.3167.3000111.3I25 V26 L27 R31 Q32 V35 W40 L43 Q103 I106 L107I25-L29 HydrophobicContact CG2-CD1 4.38Å; I25-L29 VanDerWaalsContact O-CG 3.31Å; I25-L29 WeakPolarHBondContact O-CG 3.4Å; I25-L29 PolarHBondContact O-N 2.91Å; V26-L29 WeakPolarHBondContact O-CB 3.36Å; V26-L29 PolarHBondContact O-N 3.33Å; L27-L29 VanDerWaalsContact C-N 3.34Å; L29-R31 PolarHBondContact O-N 3.34Å; L29-Q32 PolarHBondContact O-N 2.99Å; L29-V35 HydrophobicContact CD2-CB 4.29Å; L29-V35 HydrophobicContact CD2-CG2 3.68Å; L29-V35 HydrophobicContact CG-CG2 4.06Å; L29-W40 HydrophobicContact CD1-CE3 4.15Å; L29-W40 HydrophobicContact CD1-CH2 4.39Å; L29-W40 HydrophobicContact CD1-CZ3 3.46Å; L29-W40 VanDerWaalsContact CD1-CZ3 3.46Å; L29-W40 HydrophobicContact CD2-CE3 3.94Å; L29-W40 HydrophobicContact CD2-CH2 4.38Å; L29-W40 HydrophobicContact CD2-CZ3 3.37Å; L29-W40 HydrophobicContact CG-CZ3 4Å; L29-L43 HydrophobicContact CD1-CD2 3.8Å; L29-Q103 PolarHBondContact O-OE1 3.02Å; L29-I106 HydrophobicContact CD2-CG2 4.32Å; L29-L107 HydrophobicContact CB-CD1 4.28Å; L29-L107 HydrophobicContact CD1-CD1 4.16Å
30L88.3Confident90.2Very high2 Ų272.8 Ų72.81%0.0135%0.352CS..Hα-helixtrans-53.5-39.5176.2-76.8170.1000112.2V26 L27 Q32 D68 I69 F72 L107 M139V26-L30 HydrophobicContact CG1-CD1 4.19Å; V26-L30 PolarHBondContact O-N 2.87Å; L27-L30 PolarHBondContact O-N 3.19Å; L30-Q32 VanDerWaalsContact C-N 3.34Å; L30-D68 HydrophobicContact CD1-CB 4.48Å; L30-I69 HydrophobicContact CD2-CG1 4.33Å; L30-F72 HydrophobicContact CB-CD2 4.09Å; L30-F72 HydrophobicContact CB-CE2 4.45Å; L30-F72 HydrophobicContact CB-CG 4.28Å; L30-F72 HydrophobicContact CD1-CB 4.4Å; L30-F72 HydrophobicContact CD2-CD1 4.35Å; L30-F72 HydrophobicContact CD2-CG 4.41Å; L30-F72 WeakPolarHBondContact O-CE2 3.32Å; L30-F72 VanDerWaalsContact O-CZ 3.22Å; L30-F72 WeakPolarHBondContact O-CZ 3.46Å; L30-L107 HydrophobicContact CD2-CD2 3.63Å; L30-L107 HydrophobicContact CG-CD2 4.07Å; L30-M139 HydrophobicContact CD2-CE 4.22Å
31R87.7Confident90.3Very high124 Ų12473.5 Ų73.547%0.46835%0.35SS..THydrogen-bonded Turntrans-85.40.1-179.9-66174.8-174.9175.12.4114.8L27 K28 L29 E33 F72L27-R31 WeakPolarHBondContact O-CB 3.44Å; L27-R31 VanDerWaalsContact O-CG 3.28Å; L27-R31 WeakPolarHBondContact O-CG 3.38Å; L27-R31 PolarHBondContact O-N 2.99Å; K28-R31 CarbonylContact O-C 3.55Å; K28-R31 PolarHBondContact O-N 3.47Å; L29-R31 PolarHBondContact O-N 3.34Å; R31-E33 HydrophobicContact CB-CG 3.89Å; R31-E33 WeakPolarHBondContact CD-OE1 3.37Å; R31-E33 IonicContact NH1-OE1 2.69Å; R31-E33 PolarHBondContact O-N 2.9Å; R31-F72 HydrophobicContact CG-CE2 4.49Å
32Q86.3Confident90.5Very high87 Ų8769.5 Ų69.541%0.40734%0.335SS..THydrogen-bonded Turntrans57.531-173.4-43.9-160.2-37.900113.8K28 L29 L30 K99 Q103K28-Q32 PolarHBondContact O-N 2.9Å; L29-Q32 PolarHBondContact O-N 2.99Å; L30-Q32 VanDerWaalsContact C-N 3.34Å; Q32-K99 PolarHBondContact NE2-O 3.34Å; Q32-Q103 HydrophobicContact CG-CG 4.03Å
33E89.6Confident90.5Very high89 Ų8969.5 Ų69.542%0.41634%0.335SS..  trans-79.2159.1173-65.2175.1-156.800110.6K28 R31 V35K28-E33 HydrophobicContact CB-CB 3.99Å; K28-E33 HydrophobicContact CG-CB 3.99Å; K28-E33 WeakPolarHBondContact CG-OE2 3.41Å; K28-E33 PolarHBondContact O-N 3.46Å; R31-E33 HydrophobicContact CB-CG 3.89Å; R31-E33 WeakPolarHBondContact CD-OE1 3.37Å; R31-E33 IonicContact NH1-OE1 2.69Å; R31-E33 PolarHBondContact O-N 2.9Å; E33-V35 PolarHBondContact O-N 3.13Å
34S87.8Confident90.5Very high109 Ų10967.9 Ų67.976%0.76233%0.331SS*.  trans-67.9127.4-178.654.60000112.1
35V88.1Confident90.3Very high39 Ų3967.5 Ų67.524%0.23633%0.33CS..  trans-115.8126.4174.3-179.70000108.6I25 K28 L29 E33 Q39 W40I25-V35 HydrophobicContact CG2-CG1 3.79Å; I25-V35 HydrophobicContact CG2-CG2 4.39Å; K28-V35 HydrophobicContact CB-CG2 3.73Å; K28-V35 HydrophobicContact CD-CG2 4.36Å; L29-V35 HydrophobicContact CD2-CB 4.29Å; L29-V35 HydrophobicContact CD2-CG2 3.68Å; L29-V35 HydrophobicContact CG-CG2 4.06Å; E33-V35 PolarHBondContact O-N 3.13Å; V35-Q39 HydrophobicContact CG1-CB 3.6Å; V35-W40 HydrophobicContact CG1-CB 4.42Å; V35-W40 HydrophobicContact CG1-CE3 4.42Å
36T92.2Very high90.3Very high77 Ų7767.9 Ų67.947%0.47233%0.332SS..  trans-70.9156.2178.662.60000111Q38 Q39 W40T36-Q38 PolarHBondContact O-N 3.01Å; T36-Q39 PolarHBondContact O-N 3.49Å; T36-Q39 WeakPolarHBondContact OG1-CB 3.23Å; T36-Q39 VanDerWaalsContact OG1-CG 3.31Å; T36-Q39 WeakPolarHBondContact OG1-CG 3.49Å; T36-Q39 PolarHBondContact OG1-N 3.41Å; T36-Q39 PolarHBondContact OG1-OE1 2.91Å; T36-W40 PolarHBondContact O-N 2.89Å
37K90.1Very high90.2Very high196 Ų19667.8 Ų67.885%0.85233%0.332SS*.Hα-helixtrans-55.1-35.9174.9-70.2-177.4179.21790112.5W40 F41K37-W40 PolarHBondContact O-N 3.32Å; K37-F41 PolarHBondContact O-N 2.91Å
38Q90.9Very high90Very high114 Ų11469.9 Ų69.953%0.53334%0.341SS..Hα-helixtrans-65.5-51.5177.6-171.659.541.400111.2T36 W40 F41 D42T36-Q38 PolarHBondContact O-N 3.01Å; Q38-W40 PolarHBondContact O-N 3.43Å; Q38-F41 WeakPolarHBondContact O-CB 3.39Å; Q38-F41 PolarHBondContact O-N 3.35Å; Q38-D42 PolarHBondContact NE2-OD1 3.04Å; Q38-D42 WeakPolarHBondContact O-CB 3.22Å; Q38-D42 PolarHBondContact O-N 3.48Å
39Q92.1Very high89.9Confident50 Ų5067.9 Ų67.923%0.23434%0.335CS..Hα-helixtrans-56.9-39175.8-76.6164.2-33.600112.4I25 V35 T36 D42 L43I25-Q39 HydrophobicContact CD1-CB 3.92Å; I25-Q39 HydrophobicContact CD1-CG 4.16Å; I25-Q39 HydrophobicContact CG1-CB 4.16Å; I25-Q39 HydrophobicContact CG1-CG 4.28Å; I25-Q39 HydrophobicContact CG2-CB 4.34Å; V35-Q39 HydrophobicContact CG1-CB 3.6Å; T36-Q39 PolarHBondContact O-N 3.49Å; T36-Q39 WeakPolarHBondContact OG1-CB 3.23Å; T36-Q39 VanDerWaalsContact OG1-CG 3.31Å; T36-Q39 WeakPolarHBondContact OG1-CG 3.49Å; T36-Q39 PolarHBondContact OG1-N 3.41Å; T36-Q39 PolarHBondContact OG1-OE1 2.91Å; Q39-D42 PolarHBondContact O-N 3.21Å; Q39-L43 WeakPolarHBondContact O-CB 3.35Å; Q39-L43 PolarHBondContact O-N 3.29Å
40W90.1Very high89.8Confident74 Ų7467.3 Ų67.328%0.2833%0.332SS..Hα-helixtrans-63.1-47176-167.7-104.2000111.5L29 V35 T36 K37 Q38 L43 F44 I106 K109 P110L29-W40 HydrophobicContact CD1-CE3 4.15Å; L29-W40 HydrophobicContact CD1-CH2 4.39Å; L29-W40 HydrophobicContact CD1-CZ3 3.46Å; L29-W40 VanDerWaalsContact CD1-CZ3 3.46Å; L29-W40 HydrophobicContact CD2-CE3 3.94Å; L29-W40 HydrophobicContact CD2-CH2 4.38Å; L29-W40 HydrophobicContact CD2-CZ3 3.37Å; L29-W40 HydrophobicContact CG-CZ3 4Å; V35-W40 HydrophobicContact CG1-CB 4.42Å; V35-W40 HydrophobicContact CG1-CE3 4.42Å; T36-W40 PolarHBondContact O-N 2.89Å; K37-W40 PolarHBondContact O-N 3.32Å; Q38-W40 PolarHBondContact O-N 3.43Å; W40-L43 PolarHBondContact O-N 3.1Å; W40-F44 AromaticContact CD1-CE2 3.9Å; W40-F44 HydrophobicContact CD2-CE2 4.25Å; W40-F44 AromaticContact CE2-CE2 3.52Å; W40-F44 HydrophobicContact CG-CE2 4.48Å; W40-F44 AromaticContact CZ2-CE2 3.78Å; W40-F44 HydrophobicContact CZ2-CE2 3.78Å; W40-F44 HydrophobicContact CZ2-CZ 4.39Å; W40-F44 AromaticContact NE1-CD2 4Å; W40-F44 AromaticContact NE1-CE2 3.28Å; W40-F44 VanDerWaalsContact NE1-CE2 3.28Å; W40-F44 WeakPolarHBondContact O-CD2 3.38Å; W40-F44 PolarHBondContact O-N 3.25Å; W40-I106 HydrophobicContact CH2-CG2 3.71Å; W40-I106 HydrophobicContact CZ3-CG2 4.18Å; W40-K109 HydrophobicContact CZ2-CB 4.18Å; W40-K109 HydrophobicContact CZ2-CD 4.43Å; W40-P110 HydrophobicContact CH2-CG 3.71Å; W40-P110 HydrophobicContact CZ2-CG 4.01Å; W40-P110 HydrophobicContact CZ3-CG 3.99Å
41F90.6Very high89.7Confident136 Ų13667.7 Ų67.760%0.59634%0.335SS*.Hα-helixtrans-62.1-44.6175.7-179.3-92.3000112.5K37 Q38 L43 F44 S45K37-F41 PolarHBondContact O-N 2.91Å; Q38-F41 WeakPolarHBondContact O-CB 3.39Å; Q38-F41 PolarHBondContact O-N 3.35Å; F41-L43 VanDerWaalsContact C-N 3.3Å; F41-L43 PolarHBondContact O-N 2.8Å; F41-F44 PolarHBondContact O-N 3.05Å; F41-S45 WeakPolarHBondContact O-CB 3.46Å; F41-S45 PolarHBondContact O-N 3.15Å
42D91.7Very high89.6Confident57 Ų5766 Ų6631%0.30534%0.335SS..Hα-helixtrans-58.9-43.4178.9-63-23.1000110.6Q38 Q39 F44 S45 D46Q38-D42 PolarHBondContact NE2-OD1 3.04Å; Q38-D42 WeakPolarHBondContact O-CB 3.22Å; Q38-D42 PolarHBondContact O-N 3.48Å; Q39-D42 PolarHBondContact O-N 3.21Å; D42-F44 PolarHBondContact O-N 2.88Å; D42-S45 PolarHBondContact O-N 3.41Å; D42-D46 VanDerWaalsContact O-CB 3.31Å; D42-D46 WeakPolarHBondContact O-CB 3.37Å; D42-D46 PolarHBondContact O-N 3.4Å
43L92.2Very high89.5Confident0 Ų066.4 Ų66.40%033%0.332CS..Hα-helixtrans-61.1-45.8177.1-177.162.6000112.3M22 I25 V26 L29 Q39 W40 F41 S45 V47 P110 F111M22-L43 HydrophobicContact CB-CD1 3.85Å; M22-L43 HydrophobicContact CG-CD1 3.88Å; M22-L43 HydrophobicContact SD-CD1 4.23Å; I25-L43 HydrophobicContact CD1-CB 4.49Å; I25-L43 HydrophobicContact CG2-CB 4.34Å; I25-L43 HydrophobicContact CG2-CD2 3.93Å; V26-L43 HydrophobicContact CG2-CD1 4.16Å; V26-L43 HydrophobicContact CG2-CD2 4.5Å; L29-L43 HydrophobicContact CD1-CD2 3.8Å; Q39-L43 WeakPolarHBondContact O-CB 3.35Å; Q39-L43 PolarHBondContact O-N 3.29Å; W40-L43 PolarHBondContact O-N 3.1Å; F41-L43 VanDerWaalsContact C-N 3.3Å; F41-L43 PolarHBondContact O-N 2.8Å; L43-S45 VanDerWaalsContact C-N 3.34Å; L43-S45 PolarHBondContact O-N 3.32Å; L43-V47 HydrophobicContact CD1-CG2 4.08Å; L43-V47 WeakPolarHBondContact O-CB 3.31Å; L43-V47 WeakPolarHBondContact O-CG2 3.25Å; L43-V47 PolarHBondContact O-N 3.48Å; L43-P110 HydrophobicContact CD2-CB 3.75Å; L43-P110 HydrophobicContact CD2-CG 3.64Å; L43-P110 HydrophobicContact CG-CB 3.74Å; L43-P110 HydrophobicContact CG-CG 4.2Å; L43-F111 HydrophobicContact CD1-CZ 4.41Å
44F91.3Very high89.3Confident78 Ų7863.2 Ų63.234%0.34232%0.318SS..Hα-helixtrans-60.5-45174.9-89.3-99.1000111.8W40 F41 D42 H48 K109 P110W40-F44 AromaticContact CD1-CE2 3.9Å; W40-F44 HydrophobicContact CD2-CE2 4.25Å; W40-F44 AromaticContact CE2-CE2 3.52Å; W40-F44 HydrophobicContact CG-CE2 4.48Å; W40-F44 AromaticContact CZ2-CE2 3.78Å; W40-F44 HydrophobicContact CZ2-CE2 3.78Å; W40-F44 HydrophobicContact CZ2-CZ 4.39Å; W40-F44 AromaticContact NE1-CD2 4Å; W40-F44 AromaticContact NE1-CE2 3.28Å; W40-F44 VanDerWaalsContact NE1-CE2 3.28Å; W40-F44 WeakPolarHBondContact O-CD2 3.38Å; W40-F44 PolarHBondContact O-N 3.25Å; F41-F44 PolarHBondContact O-N 3.05Å; D42-F44 PolarHBondContact O-N 2.88Å; F44-H48 VanDerWaalsContact O-CB 3.3Å; F44-H48 WeakPolarHBondContact O-CB 3.32Å; F44-H48 PolarHBondContact O-N 3.1Å; F44-K109 WeakPolarHBondContact CE1-O 3.39Å; F44-K109 HydrophobicContact CZ-CB 3.94Å; F44-K109 VanDerWaalsContact CZ-O 3.25Å; F44-K109 WeakPolarHBondContact CZ-O 3.37Å; F44-P110 HydrophobicContact CD2-CB 3.74Å; F44-P110 HydrophobicContact CD2-CG 4.03Å; F44-P110 HydrophobicContact CE2-CB 3.73Å; F44-P110 HydrophobicContact CE2-CG 3.61Å; F44-P110 HydrophobicContact CG-CB 4.21Å; F44-P110 VanDerWaalsContact CZ-CA 3.5Å; F44-P110 HydrophobicContact CZ-CB 4.22Å; F44-P110 HydrophobicContact CZ-CG 4.2Å
45S89.8Confident89Confident59 Ų5965.6 Ų65.641%0.41332%0.322SS..Hα-helixtrans-65.5-45.2-178.3-179.40000111.8F41 D42 L43 H48 A49F41-S45 WeakPolarHBondContact O-CB 3.46Å; F41-S45 PolarHBondContact O-N 3.15Å; D42-S45 PolarHBondContact O-N 3.41Å; L43-S45 VanDerWaalsContact C-N 3.34Å; L43-S45 PolarHBondContact O-N 3.32Å; S45-H48 PolarHBondContact O-N 2.98Å; S45-A49 WeakPolarHBondContact O-CB 3.21Å; S45-A49 PolarHBondContact O-N 3.47Å
46D91Very high88.9Confident20 Ų2070.9 Ų70.911%0.10734%0.342CS..Hα-helixtrans-70.8-41.5-178-74.9-24.1000111.7K18 M22 D42 H48 A49 V50K18-D46 WeakPolarHBondContact CE-OD1 3.19Å; K18-D46 IonicContact NZ-OD1 3.52Å; K18-D46 PolarHBondContact NZ-OD1 2.99Å; K18-D46 IonicContact NZ-OD2 3.25Å; M22-D46 HydrophobicContact CE-CB 4.48Å; M22-D46 HydrophobicContact CG-CB 3.8Å; M22-D46 HydrophobicContact SD-CB 3.76Å; D42-D46 VanDerWaalsContact O-CB 3.31Å; D42-D46 WeakPolarHBondContact O-CB 3.37Å; D42-D46 PolarHBondContact O-N 3.4Å; D46-H48 VanDerWaalsContact C-N 3.31Å; D46-H48 PolarHBondContact O-N 3.11Å; D46-A49 PolarHBondContact O-N 3.26Å; D46-V50 WeakPolarHBondContact O-CG2 3.4Å; D46-V50 PolarHBondContact O-N 3.46Å
47V90.1Very high88.6Confident0 Ų067.2 Ų67.20%032%0.32CS..Hα-helixtrans-59.6-45172.7172.10000110.4M22 L43 C51 P110 F111M22-V47 HydrophobicContact SD-CG2 3.67Å; L43-V47 HydrophobicContact CD1-CG2 4.08Å; L43-V47 WeakPolarHBondContact O-CB 3.31Å; L43-V47 WeakPolarHBondContact O-CG2 3.25Å; L43-V47 PolarHBondContact O-N 3.48Å; V47-C51 WeakPolarHBondContact O-CB 3.15Å; V47-C51 PolarHBondContact O-N 3.4Å; V47-C51 PolarHBondContact O-SG 2.74Å; V47-P110 WeakPolarHBondContact CG1-O 3.44Å; V47-F111 HydrophobicContact CG1-CD1 3.88Å; V47-F111 HydrophobicContact CG1-CE1 4.41Å; V47-F111 HydrophobicContact CG2-CD1 3.79Å; V47-F111 HydrophobicContact CG2-CE1 3.5Å; V47-F111 VanDerWaalsContact CG2-CE1 3.5Å; V47-F111 HydrophobicContact CG2-CZ 4.21Å
48H88.7Confident88.5Confident85 Ų8558.4 Ų58.439%0.39428%0.282SS..Hα-helixtrans-62.2-43.9177-179.9-82.1000112F44 S45 D46 C51 L52 Q113F44-H48 VanDerWaalsContact O-CB 3.3Å; F44-H48 WeakPolarHBondContact O-CB 3.32Å; F44-H48 PolarHBondContact O-N 3.1Å; S45-H48 PolarHBondContact O-N 2.98Å; D46-H48 VanDerWaalsContact C-N 3.31Å; D46-H48 PolarHBondContact O-N 3.11Å; H48-C51 PolarHBondContact O-N 3.34Å; H48-L52 WeakPolarHBondContact O-CB 3.48Å; H48-L52 PolarHBondContact O-N 3.15Å; H48-L52 VanDerWaalsContact O-N 3.11Å; H48-Q113 HydrophobicContact CB-CG 4.37Å
49A88.1Confident88.3Confident17 Ų1756 Ų5614%0.1428%0.282CS..Hα-helixtrans-63.1-47.5178.600000112.2L13 S45 D46 C51 L52 W53L13-A49 HydrophobicContact CD2-CB 4.39Å; S45-A49 WeakPolarHBondContact O-CB 3.21Å; S45-A49 PolarHBondContact O-N 3.47Å; D46-A49 PolarHBondContact O-N 3.26Å; A49-C51 VanDerWaalsContact C-N 3.35Å; A49-C51 PolarHBondContact O-N 2.87Å; A49-L52 PolarHBondContact O-N 2.86Å; A49-W53 WeakPolarHBondContact O-CB 3.34Å; A49-W53 PolarHBondContact O-N 3.47Å
50V88.3Confident88.2Confident0 Ų056.4 Ų56.40%028%0.283CS..Hα-helixtrans-64.2-41178.71750000110.9L13 F15 K18 M22 D46 L52 D54 I61L13-V50 HydrophobicContact CD2-CG2 3.94Å; F15-V50 HydrophobicContact CB-CG1 4.33Å; F15-V50 HydrophobicContact CD2-CG1 4.43Å; K18-V50 HydrophobicContact CB-CG2 3.77Å; K18-V50 HydrophobicContact CG-CG2 4.03Å; M22-V50 HydrophobicContact CE-CG2 3.88Å; D46-V50 WeakPolarHBondContact O-CG2 3.4Å; D46-V50 PolarHBondContact O-N 3.46Å; V50-L52 PolarHBondContact O-N 3.2Å; V50-D54 HydrophobicContact CG1-CB 4.35Å; V50-D54 PolarHBondContact O-N 2.71Å; V50-D54 VanDerWaalsContact O-N 3.15Å; V50-I61 HydrophobicContact CB-CD1 3.82Å; V50-I61 HydrophobicContact CG1-CD1 3.49Å; V50-I61 VanDerWaalsContact CG1-CD1 3.49Å; V50-I61 HydrophobicContact CG1-CG1 4.11Å
51C87Confident88.2Confident10 Ų1052.9 Ų52.97%0.06827%0.27CS..Hα-helixtrans-65.5-25.7177.3-67.30000113.6V47 H48 A49 P58 Q113V47-C51 WeakPolarHBondContact O-CB 3.15Å; V47-C51 PolarHBondContact O-N 3.4Å; V47-C51 PolarHBondContact O-SG 2.74Å; H48-C51 PolarHBondContact O-N 3.34Å; A49-C51 VanDerWaalsContact C-N 3.35Å; A49-C51 PolarHBondContact O-N 2.87Å; C51-P58 HydrophobicContact CB-CG 4.39Å; C51-Q113 HydrophobicContact CB-CG 3.92Å
52L85Confident88.2Confident90 Ų9048.8 Ų48.847%0.47125%0.252SS..Hα-helixtrans-90.7-34.8-177.5-170.667.6000113.3H48 A49 V50H48-L52 WeakPolarHBondContact O-CB 3.48Å; H48-L52 PolarHBondContact O-N 3.15Å; H48-L52 VanDerWaalsContact O-N 3.11Å; A49-L52 PolarHBondContact O-N 2.86Å; V50-L52 PolarHBondContact O-N 3.2Å
53W84.7Confident88.1Confident95 Ų9550.4 Ų50.436%0.3626%0.258SS..Hα-helixtrans-111.6-20.3-167-59.5114.8000115.3K10 L13 A49K10-W53 HydrophobicContact CG-CE3 4.29Å; K10-W53 HydrophobicContact CG-CZ3 4.23Å; L13-W53 HydrophobicContact CB-CB 4.3Å; L13-W53 HydrophobicContact CD2-CB 4.42Å; A49-W53 WeakPolarHBondContact O-CB 3.34Å; A49-W53 PolarHBondContact O-N 3.47Å
54D84.6Confident88.1Confident21 Ų2151 Ų5111%0.11226%0.263CS..  trans-107.4110.1175-177.3-8.2000109.7F15 V50 K56 G57 P58F15-D54 WeakPolarHBondContact CB-OD2 3.32Å; F15-D54 PolarHBondContact N-OD2 3.27Å; V50-D54 HydrophobicContact CG1-CB 4.35Å; V50-D54 PolarHBondContact O-N 2.71Å; V50-D54 VanDerWaalsContact O-N 3.15Å; D54-K56 PolarHBondContact O-N 3.09Å; D54-K56 VanDerWaalsContact O-N 3.14Å; D54-K56 PolarHBondContact OD1-N 3.48Å; D54-G57 WeakPolarHBondContact O-CA 3.37Å; D54-G57 PolarHBondContact O-N 3.25Å; D54-G57 PolarHBondContact OD1-N 3.11Å; D54-G57 VanDerWaalsContact OD1-N 3.12Å; D54-P58 VanDerWaalsContact O-CD 3.22Å; D54-P58 WeakPolarHBondContact O-CD 3.34Å
55D81.8Confident88.1Confident160 Ų16047.3 Ų47.386%0.85625%0.247SC*.THydrogen-bonded Turntrans-58.2-27.7179.9-69.7-28.6000112.9
56K86.3Confident88.1Confident150 Ų15049.2 Ų49.265%0.65225%0.248SC*.THydrogen-bonded Turntrans-98.4-8.2175.2-65.4-177.8-179.5178.20112.7D54 A59 K60D54-K56 PolarHBondContact O-N 3.09Å; D54-K56 VanDerWaalsContact O-N 3.14Å; D54-K56 PolarHBondContact OD1-N 3.48Å; K56-A59 PolarHBondContact O-N 2.98Å; K56-K60 WeakPolarHBondContact O-CG 3.41Å; K56-K60 PolarHBondContact O-N 3.46Å; K56-K60 VanDerWaalsContact O-N 3.11Å
57G86.7Confident88.2Confident0 Ų053.5 Ų53.50%027%0.267CS..Hα-helixtrans-54.6-52-175.300000113.8D54 A59 K60 I61D54-G57 WeakPolarHBondContact O-CA 3.37Å; D54-G57 PolarHBondContact O-N 3.25Å; D54-G57 PolarHBondContact OD1-N 3.11Å; D54-G57 VanDerWaalsContact OD1-N 3.12Å; G57-A59 PolarHBondContact O-N 3.05Å; G57-K60 PolarHBondContact O-N 3.44Å; G57-I61 WeakPolarHBondContact O-CG1 3.31Å; G57-I61 PolarHBondContact O-N 3.01Å
58P87.1Confident88.3Confident10 Ų1054 Ų547%0.06527%0.27CS..Hα-helixtrans-53.3-47.2177.5-29.534.9000113.8C51 D54 K60 I61 H62 L114 T117 L118C51-P58 HydrophobicContact CB-CG 4.39Å; D54-P58 VanDerWaalsContact O-CD 3.22Å; D54-P58 WeakPolarHBondContact O-CD 3.34Å; P58-K60 PolarHBondContact O-N 3.1Å; P58-I61 PolarHBondContact O-N 3.24Å; P58-H62 WeakPolarHBondContact O-CB 3.36Å; P58-H62 PolarHBondContact O-N 3.43Å; P58-L114 VanDerWaalsContact CA-CD1 3.49Å; P58-L114 HydrophobicContact CB-CD1 3.77Å; P58-L114 VanDerWaalsContact O-CD1 3.26Å; P58-L114 WeakPolarHBondContact O-CD1 3.49Å; P58-T117 HydrophobicContact CB-CG2 4.27Å; P58-T117 HydrophobicContact CG-CG2 3.59Å; P58-L118 HydrophobicContact CB-CD2 3.92Å; P58-L118 HydrophobicContact CB-CG 4.28Å
59A87.6Confident88.4Confident63 Ų6350 Ų5052%0.52125%0.251SS..Hα-helixtrans-66.3-40-179.800000111.9K56 G57 H62 Q63K56-A59 PolarHBondContact O-N 2.98Å; G57-A59 PolarHBondContact O-N 3.05Å; A59-H62 PolarHBondContact O-N 3.02Å; A59-Q63 WeakPolarHBondContact O-CB 3.15Å; A59-Q63 PolarHBondContact O-N 3.15Å
60K90.6Very high88.6Confident60 Ų6052.1 Ų52.126%0.26126%0.26SS..Hα-helixtrans-65.1-44.3175.8-70-178.9-179.3-178.70112.2F15 E16 K56 G57 P58 H62 Q63 A64F15-K60 HydrophobicContact CB-CB 4.31Å; F15-K60 HydrophobicContact CB-CD 3.68Å; F15-K60 HydrophobicContact CD1-CB 3.89Å; F15-K60 HydrophobicContact CD1-CD 3.61Å; F15-K60 HydrophobicContact CD1-CG 4.36Å; F15-K60 HydrophobicContact CD2-CB 3.75Å; F15-K60 HydrophobicContact CE1-CB 4.09Å; F15-K60 HydrophobicContact CE1-CD 4.39Å; F15-K60 HydrophobicContact CE2-CB 3.95Å; F15-K60 HydrophobicContact CG-CB 3.7Å; F15-K60 HydrophobicContact CG-CD 3.7Å; F15-K60 HydrophobicContact CG-CG 4.4Å; F15-K60 HydrophobicContact CZ-CB 4.12Å; E16-K60 VanDerWaalsContact CD-NZ 3.26Å; E16-K60 IonicContact OE1-NZ 2.68Å; E16-K60 PolarHBondContact OE1-NZ 3.01Å; E16-K60 IonicContact OE2-NZ 3Å; E16-K60 PolarHBondContact OE2-NZ 3.01Å; K56-K60 WeakPolarHBondContact O-CG 3.41Å; K56-K60 PolarHBondContact O-N 3.46Å; K56-K60 VanDerWaalsContact O-N 3.11Å; G57-K60 PolarHBondContact O-N 3.44Å; P58-K60 PolarHBondContact O-N 3.1Å; K60-H62 PolarHBondContact O-N 2.89Å; K60-Q63 PolarHBondContact O-N 3.2Å; K60-A64 WeakPolarHBondContact O-CB 3.25Å; K60-A64 PolarHBondContact O-N 3.3Å
61I89.9Confident88.8Confident0 Ų056.5 Ų56.50%028%0.28CS..Hα-helixtrans-58.5-49.3174.9-69.2171.2000110.2F15 W19 V50 G57 P58 Q63 A64 L65 F111 L114F15-I61 HydrophobicContact CD2-CG1 3.78Å; F15-I61 HydrophobicContact CE2-CB 4.48Å; F15-I61 HydrophobicContact CE2-CG1 3.81Å; W19-I61 HydrophobicContact CZ3-CG2 4.16Å; V50-I61 HydrophobicContact CB-CD1 3.82Å; V50-I61 HydrophobicContact CG1-CD1 3.49Å; V50-I61 VanDerWaalsContact CG1-CD1 3.49Å; V50-I61 HydrophobicContact CG1-CG1 4.11Å; G57-I61 WeakPolarHBondContact O-CG1 3.31Å; G57-I61 PolarHBondContact O-N 3.01Å; P58-I61 PolarHBondContact O-N 3.24Å; I61-Q63 VanDerWaalsContact C-N 3.33Å; I61-Q63 PolarHBondContact O-N 3.44Å; I61-A64 PolarHBondContact O-N 3.45Å; I61-L65 HydrophobicContact CG2-CD1 3.89Å; I61-L65 HydrophobicContact CG2-CG 4.26Å; I61-L65 WeakPolarHBondContact O-CB 3.47Å; I61-L65 VanDerWaalsContact O-CG 3.32Å; I61-L65 WeakPolarHBondContact O-CG 3.28Å; I61-L65 PolarHBondContact O-N 2.93Å; I61-F111 HydrophobicContact CG2-CD1 3.96Å; I61-F111 HydrophobicContact CG2-CE1 3.79Å; I61-L114 HydrophobicContact CB-CD1 4.22Å; I61-L114 HydrophobicContact CG2-CD1 4.27Å; I61-L114 HydrophobicContact CG2-CD2 3.82Å
62H89.2Confident89.1Confident49 Ų4957 Ų5723%0.22728%0.281CS..Hα-helixtrans-60.8-42.3-179.3-179.1-90000112.2P58 A59 K60 K66 L114 L118P58-H62 WeakPolarHBondContact O-CB 3.36Å; P58-H62 PolarHBondContact O-N 3.43Å; A59-H62 PolarHBondContact O-N 3.02Å; K60-H62 PolarHBondContact O-N 2.89Å; H62-K66 WeakPolarHBondContact O-CB 3.48Å; H62-K66 PolarHBondContact O-N 3.35Å; H62-L114 HydrophobicContact CB-CD2 4.45Å; H62-L118 HydrophobicContact CB-CD1 4.2Å
63Q90.5Very high89.4Confident91 Ų9152.7 Ų52.743%0.42526%0.259SS..Hα-helixtrans-65.9-44.4176.8-179.159.12900112.2A59 K60 I61 K66 E67A59-Q63 WeakPolarHBondContact O-CB 3.15Å; A59-Q63 PolarHBondContact O-N 3.15Å; K60-Q63 PolarHBondContact O-N 3.2Å; I61-Q63 VanDerWaalsContact C-N 3.33Å; I61-Q63 PolarHBondContact O-N 3.44Å; Q63-K66 WeakPolarHBondContact O-CB 3.45Å; Q63-K66 PolarHBondContact O-N 2.97Å; Q63-E67 PolarHBondContact NE2-OE1 3.41Å; Q63-E67 PolarHBondContact O-N 3.33Å; Q63-E67 VanDerWaalsContact O-N 3.1Å
64A91.5Very high89.8Confident13 Ų1352.9 Ų52.911%0.10726%0.262CS..Hα-helixtrans-66.3-39.117900000112.1F15 W19 K60 I61 K66 E67 D68F15-A64 HydrophobicContact CZ-CB 3.98Å; W19-A64 HydrophobicContact CD2-CB 4.24Å; W19-A64 VanDerWaalsContact CE2-CB 3.47Å; W19-A64 HydrophobicContact CH2-CB 3.93Å; W19-A64 HydrophobicContact CZ2-CB 3.31Å; K60-A64 WeakPolarHBondContact O-CB 3.25Å; K60-A64 PolarHBondContact O-N 3.3Å; I61-A64 PolarHBondContact O-N 3.45Å; A64-K66 VanDerWaalsContact C-N 3.34Å; A64-K66 PolarHBondContact O-N 3.32Å; A64-E67 PolarHBondContact O-N 3.23Å; A64-D68 PolarHBondContact O-N 2.88Å
65L91.1Very high90.1Very high1 Ų155.3 Ų55.31%0.00527%0.273CS..Hα-helixtrans-59.3-44.2171.1-76.4174.4000111.8W19 V26 I61 E67 D68 I69 F111 L114 V135W19-L65 HydrophobicContact CH2-CD2 3.98Å; W19-L65 HydrophobicContact CH2-CG 4.04Å; V26-L65 HydrophobicContact CG1-CD2 3.89Å; V26-L65 HydrophobicContact CG2-CD2 4.44Å; I61-L65 HydrophobicContact CG2-CD1 3.89Å; I61-L65 HydrophobicContact CG2-CG 4.26Å; I61-L65 WeakPolarHBondContact O-CB 3.47Å; I61-L65 VanDerWaalsContact O-CG 3.32Å; I61-L65 WeakPolarHBondContact O-CG 3.28Å; I61-L65 PolarHBondContact O-N 2.93Å; L65-E67 VanDerWaalsContact C-N 3.29Å; L65-E67 PolarHBondContact O-N 3.05Å; L65-D68 PolarHBondContact O-N 2.9Å; L65-I69 HydrophobicContact CB-CD1 4.36Å; L65-I69 VanDerWaalsContact O-CB 3.25Å; L65-I69 WeakPolarHBondContact O-CB 3.3Å; L65-I69 WeakPolarHBondContact O-CD1 3.36Å; L65-I69 WeakPolarHBondContact O-CG1 3.49Å; L65-I69 PolarHBondContact O-N 2.99Å; L65-F111 HydrophobicContact CD1-CD1 3.72Å; L65-F111 HydrophobicContact CD1-CD2 4.35Å; L65-F111 HydrophobicContact CD1-CE1 3.66Å; L65-F111 HydrophobicContact CD1-CE2 4.31Å; L65-F111 HydrophobicContact CD1-CG 4.08Å; L65-F111 HydrophobicContact CD1-CZ 3.98Å; L65-F111 HydrophobicContact CD2-CE1 4.1Å; L65-F111 HydrophobicContact CD2-CE2 4.06Å; L65-F111 HydrophobicContact CD2-CZ 3.67Å; L65-F111 HydrophobicContact CG-CE1 4.24Å; L65-F111 HydrophobicContact CG-CZ 4.3Å; L65-L114 HydrophobicContact CD1-CD2 4.13Å; L65-V135 HydrophobicContact CD1-CG2 4.18Å
66K91.1Very high90.6Very high99 Ų9947.7 Ų47.743%0.4323%0.232SC..Hα-helixtrans-58-42.7177.3179172.8-175.1-176.90112H62 Q63 A64 L70 L138H62-K66 WeakPolarHBondContact O-CB 3.48Å; H62-K66 PolarHBondContact O-N 3.35Å; Q63-K66 WeakPolarHBondContact O-CB 3.45Å; Q63-K66 PolarHBondContact O-N 2.97Å; A64-K66 VanDerWaalsContact C-N 3.34Å; A64-K66 PolarHBondContact O-N 3.32Å; K66-L70 VanDerWaalsContact O-CB 3.22Å; K66-L70 WeakPolarHBondContact O-CB 3.2Å; K66-L70 PolarHBondContact O-N 2.66Å; K66-L138 HydrophobicContact CB-CD1 4.33Å; K66-L138 HydrophobicContact CB-CD2 3.93Å; K66-L138 HydrophobicContact CD-CD1 4.21Å; K66-L138 HydrophobicContact CG-CD1 4.02Å
67E92.2Very high90.9Very high109 Ų10943 Ų4351%0.50921%0.213SC..Hα-helixtrans-66.5-48.7178.7-71.4170.3-164.400112.2Q63 A64 L65 L70 E71Q63-E67 PolarHBondContact NE2-OE1 3.41Å; Q63-E67 PolarHBondContact O-N 3.33Å; Q63-E67 VanDerWaalsContact O-N 3.1Å; A64-E67 PolarHBondContact O-N 3.23Å; L65-E67 VanDerWaalsContact C-N 3.29Å; L65-E67 PolarHBondContact O-N 3.05Å; E67-L70 PolarHBondContact O-N 2.87Å; E67-E71 PolarHBondContact O-N 3.04Å
68D92Very high91.2Very high12 Ų1246.1 Ų46.16%0.06424%0.238CC..Hα-helixtrans-67.5-36.5179.9-75.7-33.8000112.1R23 L27 L30 A64 L65 F72R23-D68 IonicContact CZ-OD1 2.83Å; R23-D68 IonicContact NE-OD1 3.24Å; R23-D68 PolarHBondContact NE-OD1 2.98Å; R23-D68 VanDerWaalsContact NE-OD1 3.15Å; R23-D68 IonicContact NE-OD2 3.24Å; R23-D68 PolarHBondContact NE-OD2 3.41Å; R23-D68 IonicContact NH2-OD1 2.62Å; R23-D68 PolarHBondContact NH2-OD1 3.24Å; L27-D68 HydrophobicContact CD2-CB 4.29Å; L30-D68 HydrophobicContact CD1-CB 4.48Å; A64-D68 PolarHBondContact O-N 2.88Å; L65-D68 PolarHBondContact O-N 2.9Å; D68-F72 WeakPolarHBondContact O-CB 3.33Å; D68-F72 PolarHBondContact O-N 2.95Å
69I92.1Very high91.5Very high1 Ų150.3 Ų50.31%0.00525%0.253CS..Hα-helixtrans-64.5-45.5173.4-71.5164000110.6L30 L65 E71 F72 I73 L107 L138 M139L30-I69 HydrophobicContact CD2-CG1 4.33Å; L65-I69 HydrophobicContact CB-CD1 4.36Å; L65-I69 VanDerWaalsContact O-CB 3.25Å; L65-I69 WeakPolarHBondContact O-CB 3.3Å; L65-I69 WeakPolarHBondContact O-CD1 3.36Å; L65-I69 WeakPolarHBondContact O-CG1 3.49Å; L65-I69 PolarHBondContact O-N 2.99Å; I69-E71 VanDerWaalsContact C-N 3.34Å; I69-E71 PolarHBondContact O-N 2.79Å; I69-F72 PolarHBondContact O-N 3.26Å; I69-I73 HydrophobicContact CG2-CD1 3.67Å; I69-I73 HydrophobicContact CG2-CG1 4.44Å; I69-I73 WeakPolarHBondContact O-CB 3.16Å; I69-I73 VanDerWaalsContact O-CG1 3.3Å; I69-I73 WeakPolarHBondContact O-CG1 3.35Å; I69-I73 PolarHBondContact O-N 3.31Å; I69-L107 HydrophobicContact CD1-CD2 4.36Å; I69-L107 HydrophobicContact CG1-CD2 4.37Å; I69-L138 HydrophobicContact CD1-CD2 4.02Å; I69-L138 HydrophobicContact CD1-CG 4.41Å; I69-M139 HydrophobicContact CD1-CG 3.71Å; I69-M139 HydrophobicContact CG1-CG 4.26Å; I69-M139 HydrophobicContact CG2-CG 4.2Å
70L92.2Very high91.7Very high61 Ų6147.3 Ų47.332%0.31923%0.228SC..Hα-helixtrans-62.2-42.9179-179.266.4000111.4K66 E67 I73 K74 T142K66-L70 VanDerWaalsContact O-CB 3.22Å; K66-L70 WeakPolarHBondContact O-CB 3.2Å; K66-L70 PolarHBondContact O-N 2.66Å; E67-L70 PolarHBondContact O-N 2.87Å; L70-I73 PolarHBondContact O-N 3.32Å; L70-K74 WeakPolarHBondContact O-CG 3.43Å; L70-K74 PolarHBondContact O-N 3.05Å; L70-T142 HydrophobicContact CB-CG2 4.43Å; L70-T142 HydrophobicContact CD1-CG2 3.67Å
71E92Very high91.7Very high91 Ų9148.4 Ų48.443%0.42524%0.236SC..Hα-helixtrans-63.9-43.5177.4-177.752.9-146.400111.8E67 I69 I73 K74 Q75E67-E71 PolarHBondContact O-N 3.04Å; I69-E71 VanDerWaalsContact C-N 3.34Å; I69-E71 PolarHBondContact O-N 2.79Å; E71-I73 VanDerWaalsContact C-N 3.34Å; E71-I73 PolarHBondContact O-N 2.95Å; E71-K74 PolarHBondContact O-N 3.25Å; E71-Q75 WeakPolarHBondContact O-CG 3.42Å; E71-Q75 PolarHBondContact O-N 3.03Å; E71-Q75 VanDerWaalsContact O-N 3.13Å; E71-Q75 PolarHBondContact OE1-NE2 3.31Å; E71-Q75 VanDerWaalsContact OE1-NE2 3.1Å
72F92.3Very high91.7Very high20 Ų2052.2 Ų52.29%0.08826%0.263CS..Hα-helixtrans-58.9-44.9173.7175.5-96.8000112.2L30 R31 D68 I69 Q75 A76 F100L30-F72 HydrophobicContact CB-CD2 4.09Å; L30-F72 HydrophobicContact CB-CE2 4.45Å; L30-F72 HydrophobicContact CB-CG 4.28Å; L30-F72 HydrophobicContact CD1-CB 4.4Å; L30-F72 HydrophobicContact CD2-CD1 4.35Å; L30-F72 HydrophobicContact CD2-CG 4.41Å; L30-F72 WeakPolarHBondContact O-CE2 3.32Å; L30-F72 VanDerWaalsContact O-CZ 3.22Å; L30-F72 WeakPolarHBondContact O-CZ 3.46Å; R31-F72 HydrophobicContact CG-CE2 4.49Å; D68-F72 WeakPolarHBondContact O-CB 3.33Å; D68-F72 PolarHBondContact O-N 2.95Å; I69-F72 PolarHBondContact O-N 3.26Å; F72-Q75 PolarHBondContact O-N 3.45Å; F72-A76 PolarHBondContact O-N 2.9Å; F72-F100 HydrophobicContact CE1-CD2 4.1Å
73I92.3Very high91.7Very high0 Ų053.6 Ų53.60%027%0.27CS..Hα-helixtrans-67-37.2179.6-70171000111.2I69 L70 E71 Q75 A76 Q77 F100 T142 W143 I147I69-I73 HydrophobicContact CG2-CD1 3.67Å; I69-I73 HydrophobicContact CG2-CG1 4.44Å; I69-I73 WeakPolarHBondContact O-CB 3.16Å; I69-I73 VanDerWaalsContact O-CG1 3.3Å; I69-I73 WeakPolarHBondContact O-CG1 3.35Å; I69-I73 PolarHBondContact O-N 3.31Å; L70-I73 PolarHBondContact O-N 3.32Å; E71-I73 VanDerWaalsContact C-N 3.34Å; E71-I73 PolarHBondContact O-N 2.95Å; I73-Q75 VanDerWaalsContact C-N 3.31Å; I73-Q75 PolarHBondContact O-N 3.44Å; I73-A76 PolarHBondContact O-N 3.34Å; I73-Q77 WeakPolarHBondContact O-CB 3.36Å; I73-Q77 PolarHBondContact O-N 3.45Å; I73-F100 HydrophobicContact CD1-CE2 3.95Å; I73-F100 HydrophobicContact CD1-CZ 4.34Å; I73-F100 HydrophobicContact CG1-CE2 4.17Å; I73-T142 HydrophobicContact CD1-CG2 3.52Å; I73-W143 HydrophobicContact CD1-CB 4.34Å; I73-W143 HydrophobicContact CG1-CE3 4.23Å; I73-I147 HydrophobicContact CG2-CD1 4Å; I73-I147 HydrophobicContact CG2-CG1 4.15Å
74K92.1Very high91.4Very high99 Ų9957.9 Ų57.943%0.4329%0.289SS..Hα-helixtrans-60.8-39.4173-77176.1179.7175.80112.4L70 E71 Q77 A78L70-K74 WeakPolarHBondContact O-CG 3.43Å; L70-K74 PolarHBondContact O-N 3.05Å; E71-K74 PolarHBondContact O-N 3.25Å; K74-Q77 WeakPolarHBondContact O-CB 3.37Å; K74-Q77 PolarHBondContact O-N 3.47Å; K74-A78 PolarHBondContact O-N 3.35Å
75Q92.2Very high91.4Very high72 Ų7261.8 Ų61.834%0.33631%0.308SS..Hα-helixtrans-66.7-40175.4-66.5173.218.100111.7E71 F72 I73 A78 R79E71-Q75 WeakPolarHBondContact O-CG 3.42Å; E71-Q75 PolarHBondContact O-N 3.03Å; E71-Q75 VanDerWaalsContact O-N 3.13Å; E71-Q75 PolarHBondContact OE1-NE2 3.31Å; E71-Q75 VanDerWaalsContact OE1-NE2 3.1Å; F72-Q75 PolarHBondContact O-N 3.45Å; I73-Q75 VanDerWaalsContact C-N 3.31Å; I73-Q75 PolarHBondContact O-N 3.44Å; Q75-A78 PolarHBondContact O-N 3.21Å; Q75-R79 PolarHBondContact O-N 3.13Å; Q75-R79 PolarHBondContact O-NH1 3.1Å
76A92.2Very high91.3Very high0 Ų064 Ų640%032%0.32CS..Hα-helixtrans-64.3-42.9172.700000111.7F72 I73 A78 R79 V80 W143 I147F72-A76 PolarHBondContact O-N 2.9Å; I73-A76 PolarHBondContact O-N 3.34Å; A76-A78 VanDerWaalsContact C-N 3.33Å; A76-A78 PolarHBondContact O-N 3.42Å; A76-R79 PolarHBondContact O-N 3.01Å; A76-R79 VanDerWaalsContact O-N 3.14Å; A76-V80 WeakPolarHBondContact O-CG2 3.47Å; A76-V80 PolarHBondContact O-N 2.86Å; A76-W143 HydrophobicContact CB-CH2 4.37Å; A76-W143 HydrophobicContact CB-CZ3 4.05Å; A76-I147 HydrophobicContact CB-CD1 4.11Å
77Q93.2Very high91.3Very high52 Ų5262.7 Ų62.724%0.24332%0.321CS..Hα-helixtrans-56.2-46.6176-174.2-17036.500111.2I73 K74 R79 V80 L81 S146 I147I73-Q77 WeakPolarHBondContact O-CB 3.36Å; I73-Q77 PolarHBondContact O-N 3.45Å; K74-Q77 WeakPolarHBondContact O-CB 3.37Å; K74-Q77 PolarHBondContact O-N 3.47Å; Q77-R79 VanDerWaalsContact C-N 3.33Å; Q77-R79 PolarHBondContact O-N 2.96Å; Q77-V80 PolarHBondContact O-N 3.23Å; Q77-L81 HydrophobicContact CG-CD1 3.64Å; Q77-L81 HydrophobicContact CG-CG 4.18Å; Q77-L81 WeakPolarHBondContact O-CB 3.46Å; Q77-L81 WeakPolarHBondContact O-CG 3.42Å; Q77-L81 PolarHBondContact O-N 2.77Å; Q77-S146 PolarHBondContact NE2-O 2.79Å; Q77-I147 HydrophobicContact CB-CD1 4.02Å; Q77-I147 HydrophobicContact CB-CG1 3.76Å; Q77-I147 HydrophobicContact CG-CG1 4.05Å
78A92.5Very high91.2Very high66 Ų6659 Ų5955%0.54531%0.309SS..Hα-helixtrans-60.8-40.1177.400000112.6K74 Q75 A76 S82K74-A78 PolarHBondContact O-N 3.35Å; Q75-A78 PolarHBondContact O-N 3.21Å; A76-A78 VanDerWaalsContact C-N 3.33Å; A76-A78 PolarHBondContact O-N 3.42Å; A78-S82 PolarHBondContact O-N 2.98Å
79R92.2Very high91.3Very high98 Ų9858.5 Ų58.537%0.3731%0.307SS..Hα-helixtrans-67.9-35.3176-69.9-170.4-66.5-822113.1Q75 A76 Q77 S82 H83 E96Q75-R79 PolarHBondContact O-N 3.13Å; Q75-R79 PolarHBondContact O-NH1 3.1Å; A76-R79 PolarHBondContact O-N 3.01Å; A76-R79 VanDerWaalsContact O-N 3.14Å; Q77-R79 VanDerWaalsContact C-N 3.33Å; Q77-R79 PolarHBondContact O-N 2.96Å; R79-S82 PolarHBondContact O-OG 3.4Å; R79-H83 PolarHBondContact O-CD2 3.5Å; R79-E96 IonicContact CZ-OE2 2.88Å; R79-E96 VanDerWaalsContact NE-CD 3.3Å; R79-E96 IonicContact NE-OE1 2.74Å; R79-E96 PolarHBondContact NE-OE1 3.4Å; R79-E96 IonicContact NE-OE2 3.15Å; R79-E96 PolarHBondContact NE-OE2 3.33Å; R79-E96 IonicContact NH2-OE2 3.47Å; R79-E96 PolarHBondContact NH2-OE2 2.77Å
80V91.5Very high91.4Very high0 Ų058.7 Ų58.70%031%0.307CS..Hα-helixtrans-74.3-49.6178.2174.20000110.2A76 Q77 S82 H83 L89 Y93 E96 I147 I151A76-V80 WeakPolarHBondContact O-CG2 3.47Å; A76-V80 PolarHBondContact O-N 2.86Å; Q77-V80 PolarHBondContact O-N 3.23Å; V80-S82 VanDerWaalsContact C-N 3.25Å; V80-S82 PolarHBondContact O-N 3.18Å; V80-H83 PolarHBondContact O-N 2.87Å; V80-L89 HydrophobicContact CG1-CD1 3.75Å; V80-L89 WeakPolarHBondContact O-CD1 3.3Å; V80-Y93 HydrophobicContact CG1-CD2 4.38Å; V80-E96 HydrophobicContact CG2-CB 4.14Å; V80-E96 HydrophobicContact CG2-CG 4.06Å; V80-I147 HydrophobicContact CG1-CG2 4.5Å; V80-I151 HydrophobicContact CG1-CD1 3.82Å
81L90.4Very high91.5Very high82 Ų8261.3 Ų61.343%0.42932%0.316SS..Hα-helixtrans-76.3-6.3-174.2-62.2-176.7000114.2Q77 H83 I151Q77-L81 HydrophobicContact CG-CD1 3.64Å; Q77-L81 HydrophobicContact CG-CG 4.18Å; Q77-L81 WeakPolarHBondContact O-CB 3.46Å; Q77-L81 WeakPolarHBondContact O-CG 3.42Å; Q77-L81 PolarHBondContact O-N 2.77Å; L81-H83 PolarHBondContact O-N 3.24Å; L81-I151 HydrophobicContact CD2-CG2 3.76Å
82S90.8Very high91.6Very high81 Ų8157.8 Ų57.857%0.56630%0.303SS*.THydrogen-bonded Turntrans-67.4-16.5170.460.20000113.2A78 R79 V80A78-S82 PolarHBondContact O-N 2.98Å; R79-S82 PolarHBondContact O-OG 3.4Å; V80-S82 VanDerWaalsContact C-N 3.25Å; V80-S82 PolarHBondContact O-N 3.18Å
83H89.1Confident91.7Very high78 Ų7856.9 Ų56.936%0.36130%0.299SS..  trans-96.7116.2179.6-64-77.3000111.3R79 V80 L81 A88 L89 A92R79-H83 PolarHBondContact O-CD2 3.5Å; V80-H83 PolarHBondContact O-N 2.87Å; L81-H83 PolarHBondContact O-N 3.24Å; H83-A88 HydrophobicContact CB-CB 4.02Å; H83-L89 HydrophobicContact CB-CB 4.45Å; H83-A92 VanDerWaalsContact CD2-CB 3.48Å; H83-A92 WeakPolarHBondContact CD2-CB 3.17Å
84Q84.7Confident91.8Very high180 Ų18057.1 Ų57.184%0.84130%0.3SS*.  trans-82.2-35.1176.3-67.5-171.6-3.300113.1R154Q84-R154 PolarHBondContact O-NH2 3.08Å
85D90.8Very high91.8Very high95 Ų9556.1 Ų56.151%0.50830%0.302SS..SBendtrans-67.8134.9177172.270.8000111.4T87 A88 L89D85-T87 VanDerWaalsContact C-N 3.3Å; D85-T87 PolarHBondContact O-N 3.41Å; D85-T87 WeakPolarHBondContact OD2-CA 3.44Å; D85-T87 WeakPolarHBondContact OD2-CB 3.5Å; D85-T87 PolarHBondContact OD2-N 3.31Å; D85-A88 HydrophobicContact CB-CB 4.18Å; D85-A88 PolarHBondContact O-N 2.8Å; D85-A88 PolarHBondContact OD2-N 2.95Å; D85-L89 VanDerWaalsContact O-CB 3.23Å; D85-L89 WeakPolarHBondContact O-CB 3.05Å; D85-L89 PolarHBondContact O-N 3.24Å
86D90.1Very high91.9Very high48 Ų4853.3 Ų53.326%0.25729%0.289SS..Hα-helixtrans-61.9-34.2-176-80.8-15.3000113.3L90 R154 S158D86-L90 WeakPolarHBondContact O-CB 3.09Å; D86-L90 PolarHBondContact O-N 3.24Å; D86-R154 IonicContact OD1-CZ 3.92Å; D86-R154 VanDerWaalsContact OD1-CZ 3.24Å; D86-R154 IonicContact OD1-NE 3.96Å; D86-R154 PolarHBondContact OD1-NE 3.15Å; D86-R154 IonicContact OD1-NH2 2.7Å; D86-R154 PolarHBondContact OD1-NH2 3.34Å; D86-S158 WeakPolarHBondContact CB-OG 3.34Å
87T89.4Confident92Very high72 Ų7253.3 Ų53.344%0.44229%0.289SS..Hα-helixtrans-74.9-44.4-179.5-51.90000110.7D85 L90 K91D85-T87 VanDerWaalsContact C-N 3.3Å; D85-T87 PolarHBondContact O-N 3.41Å; D85-T87 WeakPolarHBondContact OD2-CA 3.44Å; D85-T87 WeakPolarHBondContact OD2-CB 3.5Å; D85-T87 PolarHBondContact OD2-N 3.31Å; T87-L90 PolarHBondContact O-N 3.4Å; T87-K91 WeakPolarHBondContact O-CG 3.47Å; T87-K91 PolarHBondContact O-N 2.78Å; T87-K91 VanDerWaalsContact O-N 3.13Å
88A91.8Very high91.9Very high32 Ų3256.7 Ų56.726%0.26430%0.299SS..Hα-helixtrans-64.2-41.5174.900000111.5H83 D85 K91 A92H83-A88 HydrophobicContact CB-CB 4.02Å; D85-A88 HydrophobicContact CB-CB 4.18Å; D85-A88 PolarHBondContact O-N 2.8Å; D85-A88 PolarHBondContact OD2-N 2.95Å; A88-K91 PolarHBondContact O-N 3.49Å; A88-A92 WeakPolarHBondContact O-CB 3.36Å; A88-A92 PolarHBondContact O-N 3.42Å
89L93.5Very high91.8Very high1 Ų157.5 Ų57.51%0.00529%0.291CS..Hα-helixtrans-57.4-48.8175-179.573.5000111.4V80 H83 D85 A92 Y93 R154 L155V80-L89 HydrophobicContact CG1-CD1 3.75Å; V80-L89 WeakPolarHBondContact O-CD1 3.3Å; H83-L89 HydrophobicContact CB-CB 4.45Å; D85-L89 VanDerWaalsContact O-CB 3.23Å; D85-L89 WeakPolarHBondContact O-CB 3.05Å; D85-L89 PolarHBondContact O-N 3.24Å; L89-A92 PolarHBondContact O-N 3.05Å; L89-Y93 WeakPolarHBondContact O-CB 3.42Å; L89-Y93 PolarHBondContact O-N 3.3Å; L89-R154 HydrophobicContact CD2-CB 4.23Å; L89-L155 HydrophobicContact CG-CD2 4.48Å
90L93.7Very high91.8Very high4 Ų452.9 Ų52.92%0.02127%0.273CS..Hα-helixtrans-59.9-47.9178.1176.760.6000111.6D86 T87 A92 Y93 I94 L155 L162 L176 V180D86-L90 WeakPolarHBondContact O-CB 3.09Å; D86-L90 PolarHBondContact O-N 3.24Å; T87-L90 PolarHBondContact O-N 3.4Å; L90-A92 PolarHBondContact O-N 3.15Å; L90-Y93 PolarHBondContact O-N 3.48Å; L90-I94 HydrophobicContact CD1-CD1 4.37Å; L90-I94 HydrophobicContact CD1-CG1 3.9Å; L90-I94 HydrophobicContact CG-CG1 4.47Å; L90-I94 WeakPolarHBondContact O-CG1 3.23Å; L90-I94 PolarHBondContact O-N 3Å; L90-L155 HydrophobicContact CB-CD2 4.31Å; L90-L155 HydrophobicContact CD1-CD2 3.89Å; L90-L162 HydrophobicContact CD2-CD1 3.73Å; L90-L176 HydrophobicContact CD2-CB 4.06Å; L90-L176 HydrophobicContact CG-CB 4.37Å; L90-L176 HydrophobicContact CG-CD2 4.35Å; L90-V180 HydrophobicContact CD1-CG2 3.47Å; L90-V180 VanDerWaalsContact CD1-CG2 3.47Å
91K93.9Very high91.7Very high117 Ų11754.7 Ų54.751%0.50928%0.281SS..Hα-helixtrans-60.6-46.4178.4-72.2177.4-179.9178.80111.8T87 A88 I94 V95 L176T87-K91 WeakPolarHBondContact O-CG 3.47Å; T87-K91 PolarHBondContact O-N 2.78Å; T87-K91 VanDerWaalsContact O-N 3.13Å; A88-K91 PolarHBondContact O-N 3.49Å; K91-I94 PolarHBondContact O-N 3.41Å; K91-V95 WeakPolarHBondContact O-CG2 3.18Å; K91-V95 PolarHBondContact O-N 3.06Å; K91-V95 VanDerWaalsContact O-N 3.09Å; K91-L176 HydrophobicContact CG-CD1 4.34Å; K91-L176 HydrophobicContact CG-CD2 3.92Å
92A94Very high91.7Very high17 Ų1754 Ų5414%0.1428%0.28CS..Hα-helixtrans-62.2-45.5178.600000111.7H83 A88 L89 L90 I94 V95 E96H83-A92 VanDerWaalsContact CD2-CB 3.48Å; H83-A92 WeakPolarHBondContact CD2-CB 3.17Å; A88-A92 WeakPolarHBondContact O-CB 3.36Å; A88-A92 PolarHBondContact O-N 3.42Å; L89-A92 PolarHBondContact O-N 3.05Å; L90-A92 PolarHBondContact O-N 3.15Å; A92-I94 PolarHBondContact O-N 2.5Å; A92-V95 PolarHBondContact O-N 3.49Å; A92-E96 PolarHBondContact O-N 2.94Å; A92-E96 VanDerWaalsContact O-N 3.13Å
93Y95.3Very high91.6Very high0 Ų050.5 Ų50.50%026%0.255CS..Hα-helixtrans-57.5-48.3176.1176-97.7000111.8V80 L89 L90 V95 E96 W97 W143 I147 F148 I151 L155 S183V80-Y93 HydrophobicContact CG1-CD2 4.38Å; L89-Y93 WeakPolarHBondContact O-CB 3.42Å; L89-Y93 PolarHBondContact O-N 3.3Å; L90-Y93 PolarHBondContact O-N 3.48Å; Y93-V95 VanDerWaalsContact C-N 3.35Å; Y93-V95 PolarHBondContact O-N 3.25Å; Y93-E96 PolarHBondContact O-N 3.26Å; Y93-W97 HydrophobicContact CD1-CB 4.42Å; Y93-W97 HydrophobicContact CE1-CB 4.03Å; Y93-W97 HydrophobicContact CE1-CG 4.25Å; Y93-W97 WeakPolarHBondContact O-CB 3.32Å; Y93-W97 PolarHBondContact O-N 3.27Å; Y93-W143 HydrophobicContact CD2-CZ2 4.22Å; Y93-W143 AromaticContact CE2-CE2 3.91Å; Y93-W143 AromaticContact CE2-CZ2 3.7Å; Y93-W143 HydrophobicContact CE2-CZ2 3.7Å; Y93-W143 AromaticContact CE2-NE1 3.54Å; Y93-W143 AromaticContact CZ-NE1 3.73Å; Y93-W143 PolarHBondContact OH-NE1 3.42Å; Y93-W143 VanDerWaalsContact OH-NE1 3.13Å; Y93-I147 HydrophobicContact CD2-CG2 3.91Å; Y93-I147 HydrophobicContact CE2-CG2 3.85Å; Y93-F148 HydrophobicContact CE2-CD2 4.38Å; Y93-F148 AromaticContact CZ-CD2 3.87Å; Y93-F148 WeakPolarHBondContact OH-CD2 3.27Å; Y93-I151 HydrophobicContact CD2-CD1 3.76Å; Y93-I151 HydrophobicContact CE2-CD1 4.32Å; Y93-I151 HydrophobicContact CG-CD1 4.37Å; Y93-L155 HydrophobicContact CD1-CD1 3.51Å; Y93-L155 HydrophobicContact CD1-CD2 4.14Å; Y93-L155 HydrophobicContact CD1-CG 4.47Å; Y93-L155 HydrophobicContact CD2-CD1 3.9Å; Y93-L155 HydrophobicContact CE1-CD1 3.66Å; Y93-L155 HydrophobicContact CE2-CD1 4.01Å; Y93-L155 HydrophobicContact CG-CD1 3.64Å; Y93-L155 HydrophobicContact CG-CD2 4.03Å; Y93-S183 WeakPolarHBondContact CE1-OG 3.34Å; Y93-S183 WeakPolarHBondContact OH-CB 3.47Å; Y93-S183 PolarHBondContact OH-OG 2.95Å
94I94.4Very high91.6Very high6 Ų646.8 Ų46.83%0.03124%0.238CC..Hα-helixtrans-66.8-36.9-176.4-64.5-69.8000111.8L90 K91 A92 R98 L176 V180L90-I94 HydrophobicContact CD1-CD1 4.37Å; L90-I94 HydrophobicContact CD1-CG1 3.9Å; L90-I94 HydrophobicContact CG-CG1 4.47Å; L90-I94 WeakPolarHBondContact O-CG1 3.23Å; L90-I94 PolarHBondContact O-N 3Å; K91-I94 PolarHBondContact O-N 3.41Å; A92-I94 PolarHBondContact O-N 2.5Å; I94-R98 HydrophobicContact CG2-CG 4.33Å; I94-R98 WeakPolarHBondContact O-CB 3.28Å; I94-R98 VanDerWaalsContact O-CG 3.25Å; I94-R98 WeakPolarHBondContact O-CG 3.39Å; I94-R98 PolarHBondContact O-N 3.31Å; I94-L176 HydrophobicContact CB-CD2 4.25Å; I94-L176 HydrophobicContact CG1-CD2 4.17Å; I94-L176 HydrophobicContact CG2-CD2 4.41Å; I94-V180 HydrophobicContact CD1-CG2 4.15Å
95V93Very high91.7Very high77 Ų7741.3 Ų41.347%0.46721%0.214SC..Hα-helixtrans-61.1-47.7174.1169.10000110.8K91 A92 Y93 K99K91-V95 WeakPolarHBondContact O-CG2 3.18Å; K91-V95 PolarHBondContact O-N 3.06Å; K91-V95 VanDerWaalsContact O-N 3.09Å; A92-V95 PolarHBondContact O-N 3.49Å; Y93-V95 VanDerWaalsContact C-N 3.35Å; Y93-V95 PolarHBondContact O-N 3.25Å; V95-K99 WeakPolarHBondContact O-CG 3.5Å; V95-K99 PolarHBondContact O-N 3.01Å
96E93.2Very high91.6Very high13 Ų1339.2 Ų39.26%0.06120%0.202CC..Hα-helixtrans-71.5-39.8-179.8-65.6-60.5132.200112R79 V80 A92 Y93 K99 F100 W143R79-E96 IonicContact CZ-OE2 2.88Å; R79-E96 VanDerWaalsContact NE-CD 3.3Å; R79-E96 IonicContact NE-OE1 2.74Å; R79-E96 PolarHBondContact NE-OE1 3.4Å; R79-E96 IonicContact NE-OE2 3.15Å; R79-E96 PolarHBondContact NE-OE2 3.33Å; R79-E96 IonicContact NH2-OE2 3.47Å; R79-E96 PolarHBondContact NH2-OE2 2.77Å; V80-E96 HydrophobicContact CG2-CB 4.14Å; V80-E96 HydrophobicContact CG2-CG 4.06Å; A92-E96 PolarHBondContact O-N 2.94Å; A92-E96 VanDerWaalsContact O-N 3.13Å; Y93-E96 PolarHBondContact O-N 3.26Å; E96-K99 PolarHBondContact O-N 3.19Å; E96-K99 IonicContact OE1-NZ 3.4Å; E96-K99 PolarHBondContact OE1-NZ 3.31Å; E96-F100 VanDerWaalsContact O-CB 3.3Å; E96-F100 WeakPolarHBondContact O-CB 3.31Å; E96-F100 PolarHBondContact O-N 2.9Å; E96-W143 HydrophobicContact CB-CH2 3.92Å
97W93.9Very high91.6Very high0 Ų036.9 Ų36.90%019%0.19CC..Hα-helixtrans-59.7-47175.7174.9-113.1000111.8Y93 K99 F100 F101 L140 W143 N186 L187Y93-W97 HydrophobicContact CD1-CB 4.42Å; Y93-W97 HydrophobicContact CE1-CB 4.03Å; Y93-W97 HydrophobicContact CE1-CG 4.25Å; Y93-W97 WeakPolarHBondContact O-CB 3.32Å; Y93-W97 PolarHBondContact O-N 3.27Å; W97-K99 VanDerWaalsContact C-N 3.33Å; W97-K99 PolarHBondContact O-N 3.29Å; W97-F100 AromaticContact CE3-CD1 3.8Å; W97-F100 HydrophobicContact CE3-CD1 3.8Å; W97-F100 HydrophobicContact CE3-CE1 4.38Å; W97-F100 AromaticContact CZ3-CD1 3.68Å; W97-F100 HydrophobicContact CZ3-CD1 3.68Å; W97-F100 AromaticContact CZ3-CE1 3.81Å; W97-F100 HydrophobicContact CZ3-CE1 3.81Å; W97-F100 PolarHBondContact O-N 2.96Å; W97-F101 HydrophobicContact CD2-CB 4.5Å; W97-F101 AromaticContact CH2-CD2 3.95Å; W97-F101 HydrophobicContact CH2-CD2 3.95Å; W97-F101 HydrophobicContact CZ2-CB 4.45Å; W97-F101 AromaticContact CZ2-CD2 3.62Å; W97-F101 HydrophobicContact CZ2-CD2 3.62Å; W97-F101 HydrophobicContact CZ2-CE2 4.19Å; W97-F101 HydrophobicContact CZ2-CG 4.24Å; W97-F101 WeakPolarHBondContact O-CB 3.46Å; W97-F101 PolarHBondContact O-N 3.22Å; W97-L140 HydrophobicContact CH2-CD2 4.06Å; W97-W143 HydrophobicContact CB-CZ2 4.03Å; W97-W143 AromaticContact CE3-CD1 3.73Å; W97-W143 AromaticContact CE3-CD2 3.99Å; W97-W143 HydrophobicContact CE3-CD2 3.99Å; W97-W143 AromaticContact CE3-CE2 3.44Å; W97-W143 VanDerWaalsContact CE3-CE2 3.44Å; W97-W143 HydrophobicContact CE3-CG 4.17Å; W97-W143 AromaticContact CE3-CZ2 3.84Å; W97-W143 HydrophobicContact CE3-CZ2 3.84Å; W97-W143 AromaticContact CE3-NE1 3.23Å; W97-W143 AromaticContact CZ3-CD1 3.44Å; W97-W143 VanDerWaalsContact CZ3-CD1 3.44Å; W97-W143 HydrophobicContact CZ3-CD2 4.13Å; W97-W143 AromaticContact CZ3-CE2 3.95Å; W97-W143 AromaticContact CZ3-CG 3.85Å; W97-W143 HydrophobicContact CZ3-CG 3.85Å; W97-W143 AromaticContact CZ3-NE1 3.48Å; W97-N186 HydrophobicContact CZ2-CB 4.45Å; W97-L187 HydrophobicContact CH2-CD1 4.04Å; W97-L187 HydrophobicContact CH2-CD2 3.63Å; W97-L187 HydrophobicContact CH2-CG 3.72Å; W97-L187 HydrophobicContact CZ3-CD1 4.09Å; W97-L187 HydrophobicContact CZ3-CD2 3.79Å; W97-L187 HydrophobicContact CZ3-CG 4.14Å
98R91.6Very high91.6Very high123 Ų12333.6 Ų33.646%0.46417%0.17SC..Hα-helixtrans-62.9-40179.6-74178.970.1-172.62.6112.4I94 T102I94-R98 HydrophobicContact CG2-CG 4.33Å; I94-R98 WeakPolarHBondContact O-CB 3.28Å; I94-R98 VanDerWaalsContact O-CG 3.25Å; I94-R98 WeakPolarHBondContact O-CG 3.39Å; I94-R98 PolarHBondContact O-N 3.31Å; R98-T102 PolarHBondContact O-N 3.47Å; R98-T102 PolarHBondContact O-OG1 3.22Å
99K90.2Very high91.5Very high84 Ų8436.9 Ų36.937%0.36518%0.178SC..Hα-helixtrans-62.2-49.3174.7-69.6172.6-171.1170.40110.5Q32 V95 E96 W97 Q103Q32-K99 PolarHBondContact NE2-O 3.34Å; V95-K99 WeakPolarHBondContact O-CG 3.5Å; V95-K99 PolarHBondContact O-N 3.01Å; E96-K99 PolarHBondContact O-N 3.19Å; E96-K99 IonicContact OE1-NZ 3.4Å; E96-K99 PolarHBondContact OE1-NZ 3.31Å; W97-K99 VanDerWaalsContact C-N 3.33Å; W97-K99 PolarHBondContact O-N 3.29Å; K99-Q103 PolarHBondContact O-N 3.06Å
100F92.2Very high91.2Very high1 Ų137 Ų370%0.00418%0.179CC..Hα-helixtrans-64.3-45.8-179.2172.2-100.9000112.9F72 I73 E96 W97 T102 Q103 C104 M139 L140 W143F72-F100 HydrophobicContact CE1-CD2 4.1Å; I73-F100 HydrophobicContact CD1-CE2 3.95Å; I73-F100 HydrophobicContact CD1-CZ 4.34Å; I73-F100 HydrophobicContact CG1-CE2 4.17Å; E96-F100 VanDerWaalsContact O-CB 3.3Å; E96-F100 WeakPolarHBondContact O-CB 3.31Å; E96-F100 PolarHBondContact O-N 2.9Å; W97-F100 AromaticContact CE3-CD1 3.8Å; W97-F100 HydrophobicContact CE3-CD1 3.8Å; W97-F100 HydrophobicContact CE3-CE1 4.38Å; W97-F100 AromaticContact CZ3-CD1 3.68Å; W97-F100 HydrophobicContact CZ3-CD1 3.68Å; W97-F100 AromaticContact CZ3-CE1 3.81Å; W97-F100 HydrophobicContact CZ3-CE1 3.81Å; W97-F100 PolarHBondContact O-N 2.96Å; F100-T102 VanDerWaalsContact C-N 3.34Å; F100-T102 PolarHBondContact O-N 3.46Å; F100-Q103 CarbonylContact O-C 3.6Å; F100-Q103 WeakPolarHBondContact O-CA 3.43Å; F100-Q103 WeakPolarHBondContact O-CB 3.29Å; F100-Q103 PolarHBondContact O-N 2.97Å; F100-C104 WeakPolarHBondContact CE1-SG 3.5Å; F100-C104 VanDerWaalsContact CZ-SG 3.54Å; F100-C104 PolarHBondContact O-N 3.44Å; F100-C104 PolarHBondContact O-SG 3.02Å; F100-C104 VanDerWaalsContact O-SG 3.39Å; F100-M139 HydrophobicContact CD2-CE 4.28Å; F100-M139 HydrophobicContact CE2-CB 4.11Å; F100-M139 HydrophobicContact CE2-CE 3.79Å; F100-M139 HydrophobicContact CZ-CB 3.76Å; F100-M139 HydrophobicContact CZ-CE 4.38Å; F100-M139 WeakPolarHBondContact CZ-O 3.42Å; F100-L140 HydrophobicContact CE1-CD2 4.3Å; F100-W143 HydrophobicContact CB-CE3 3.92Å; F100-W143 HydrophobicContact CB-CH2 4.07Å; F100-W143 HydrophobicContact CB-CZ3 3.56Å; F100-W143 HydrophobicContact CD1-CB 4.38Å; F100-W143 AromaticContact CD1-CD2 3.71Å; F100-W143 HydrophobicContact CD1-CD2 3.71Å; F100-W143 AromaticContact CD1-CE3 3.49Å; F100-W143 HydrophobicContact CD1-CE3 3.49Å; F100-W143 VanDerWaalsContact CD1-CE3 3.49Å; F100-W143 HydrophobicContact CD1-CG 4.09Å; F100-W143 HydrophobicContact CD1-CZ3 4.03Å; F100-W143 AromaticContact CD2-CE3 3.65Å; F100-W143 HydrophobicContact CD2-CE3 3.65Å; F100-W143 AromaticContact CD2-CZ3 3.98Å; F100-W143 HydrophobicContact CD2-CZ3 3.98Å; F100-W143 HydrophobicContact CE1-CB 3.61Å; F100-W143 AromaticContact CE1-CD2 3.86Å; F100-W143 HydrophobicContact CE1-CD2 3.86Å; F100-W143 AromaticContact CE1-CE3 3.84Å; F100-W143 HydrophobicContact CE1-CE3 3.84Å; F100-W143 AromaticContact CE1-CG 3.78Å; F100-W143 HydrophobicContact CE1-CG 3.78Å; F100-W143 AromaticContact CE2-CE3 3.98Å; F100-W143 HydrophobicContact CE2-CE3 3.98Å; F100-W143 HydrophobicContact CG-CD2 4.09Å; F100-W143 AromaticContact CG-CE3 3.38Å; F100-W143 HydrophobicContact CG-CE3 3.38Å; F100-W143 HydrophobicContact CG-CH2 4.4Å; F100-W143 AromaticContact CG-CZ3 3.57Å; F100-W143 HydrophobicContact CG-CZ3 3.57Å; F100-W143 HydrophobicContact CZ-CB 3.7Å; F100-W143 HydrophobicContact CZ-CD2 4.37Å; F100-W143 HydrophobicContact CZ-CE3 4.06Å; F100-W143 HydrophobicContact CZ-CG 4.26Å
101F90.5Very high91.1Very high37 Ų3736.8 Ų36.816%0.16218%0.178CC..Hα-helixtrans-63.4-40.2-178.8-168.2-108.1000111.5W97 Q103 C104 N186W97-F101 HydrophobicContact CD2-CB 4.5Å; W97-F101 AromaticContact CH2-CD2 3.95Å; W97-F101 HydrophobicContact CH2-CD2 3.95Å; W97-F101 HydrophobicContact CZ2-CB 4.45Å; W97-F101 AromaticContact CZ2-CD2 3.62Å; W97-F101 HydrophobicContact CZ2-CD2 3.62Å; W97-F101 HydrophobicContact CZ2-CE2 4.19Å; W97-F101 HydrophobicContact CZ2-CG 4.24Å; W97-F101 WeakPolarHBondContact O-CB 3.46Å; W97-F101 PolarHBondContact O-N 3.22Å; F101-Q103 PolarHBondContact O-N 2.99Å; F101-C104 VanDerWaalsContact O-CB 3.31Å; F101-C104 WeakPolarHBondContact O-CB 3.36Å; F101-C104 PolarHBondContact O-N 3.47Å; F101-C104 VanDerWaalsContact O-N 3.08Å; F101-N186 HydrophobicContact CE2-CB 3.8Å; F101-N186 WeakPolarHBondContact CE2-ND2 3.33Å; F101-N186 HydrophobicContact CZ-CB 4.46Å; F101-N186 WeakPolarHBondContact CZ-ND2 3.41Å
102T89.2Confident90.6Very high68 Ų6833.6 Ų33.642%0.41717%0.17SC..Hα-helixtrans-56.8-39.5170.5-570000111.8R98 F100 C104 D105 I106R98-T102 PolarHBondContact O-N 3.47Å; R98-T102 PolarHBondContact O-OG1 3.22Å; F100-T102 VanDerWaalsContact C-N 3.34Å; F100-T102 PolarHBondContact O-N 3.46Å; T102-C104 VanDerWaalsContact C-N 3.35Å; T102-D105 PolarHBondContact O-N 3.39Å; T102-I106 HydrophobicContact CG2-CD1 3.91Å; T102-I106 WeakPolarHBondContact O-CG1 3.29Å; T102-I106 PolarHBondContact O-N 3.34Å
103Q89.6Confident90.1Very high8 Ų835.3 Ų35.34%0.03718%0.175CC..Hα-helixtrans-73-25.7178.1-66.7-49.7-45.800113.3L29 Q32 K99 F100 F101 D105 I106 L107 M139L29-Q103 PolarHBondContact O-OE1 3.02Å; Q32-Q103 HydrophobicContact CG-CG 4.03Å; K99-Q103 PolarHBondContact O-N 3.06Å; F100-Q103 CarbonylContact O-C 3.6Å; F100-Q103 WeakPolarHBondContact O-CA 3.43Å; F100-Q103 WeakPolarHBondContact O-CB 3.29Å; F100-Q103 PolarHBondContact O-N 2.97Å; F101-Q103 PolarHBondContact O-N 2.99Å; Q103-D105 PolarHBondContact O-N 3.18Å; Q103-I106 PolarHBondContact O-N 2.94Å; Q103-I106 VanDerWaalsContact O-N 3.16Å; Q103-L107 VanDerWaalsContact O-CB 3.32Å; Q103-L107 WeakPolarHBondContact O-CB 3.44Å; Q103-L107 PolarHBondContact O-N 2.7Å; Q103-M139 HydrophobicContact CB-CE 4.14Å
104C89.4Confident89.6Confident0 Ų035.4 Ų35.40%018%0.176CC..Hα-helixtrans-62.5-20.5172.9-66.50000113F100 F101 T102 P108 R136F100-C104 WeakPolarHBondContact CE1-SG 3.5Å; F100-C104 VanDerWaalsContact CZ-SG 3.54Å; F100-C104 PolarHBondContact O-N 3.44Å; F100-C104 PolarHBondContact O-SG 3.02Å; F100-C104 VanDerWaalsContact O-SG 3.39Å; F101-C104 VanDerWaalsContact O-CB 3.31Å; F101-C104 WeakPolarHBondContact O-CB 3.36Å; F101-C104 PolarHBondContact O-N 3.47Å; F101-C104 VanDerWaalsContact O-N 3.08Å; T102-C104 VanDerWaalsContact C-N 3.35Å; C104-P108 VanDerWaalsContact O-CD 3.24Å; C104-P108 WeakPolarHBondContact O-CD 3.15Å; C104-P108 WeakPolarHBondContact O-CG 3.22Å; C104-R136 HydrophobicContact CB-CG 4.28Å
105D86.6Confident88.8Confident64 Ų6436 Ų3634%0.34218%0.178SC..Hα-helixtrans-96.7-21.5175.9-64.3-26.3000112.9T102 Q103 K109 R136T102-D105 PolarHBondContact O-N 3.39Å; Q103-D105 PolarHBondContact O-N 3.18Å; D105-K109 WeakPolarHBondContact O-CE 3.17Å; D105-R136 IonicContact OD1-NE 3.17Å
106I88.4Confident88.2Confident51 Ų5137.1 Ų37.126%0.26218%0.181SC..Hα-helixtrans-94.2-51.9-176.6-63.8172.1000111L29 W40 T102 Q103 K109L29-I106 HydrophobicContact CD2-CG2 4.32Å; W40-I106 HydrophobicContact CH2-CG2 3.71Å; W40-I106 HydrophobicContact CZ3-CG2 4.18Å; T102-I106 HydrophobicContact CG2-CD1 3.91Å; T102-I106 WeakPolarHBondContact O-CG1 3.29Å; T102-I106 PolarHBondContact O-N 3.34Å; Q103-I106 PolarHBondContact O-N 2.94Å; Q103-I106 VanDerWaalsContact O-N 3.16Å; I106-K109 PolarHBondContact O-N 2.77Å
107L90Very high87.7Confident0 Ų039 Ų390%019%0.193CC..THydrogen-bonded Turntrans-60.5-36.9-172.5-177.763.3000113.3V26 L29 L30 I69 Q103 K109 P110 F111 V135 M139V26-L107 HydrophobicContact CG1-CD1 4.23Å; L29-L107 HydrophobicContact CB-CD1 4.28Å; L29-L107 HydrophobicContact CD1-CD1 4.16Å; L30-L107 HydrophobicContact CD2-CD2 3.63Å; L30-L107 HydrophobicContact CG-CD2 4.07Å; I69-L107 HydrophobicContact CD1-CD2 4.36Å; I69-L107 HydrophobicContact CG1-CD2 4.37Å; Q103-L107 VanDerWaalsContact O-CB 3.32Å; Q103-L107 WeakPolarHBondContact O-CB 3.44Å; Q103-L107 PolarHBondContact O-N 2.7Å; L107-K109 VanDerWaalsContact C-N 3.28Å; L107-K109 PolarHBondContact O-N 3.3Å; L107-P110 WeakPolarHBondContact O-CD 3.28Å; L107-F111 HydrophobicContact CD1-CE2 3.98Å; L107-F111 VanDerWaalsContact O-CD2 3.23Å; L107-F111 WeakPolarHBondContact O-CD2 3.47Å; L107-V135 HydrophobicContact CD2-CG1 4.49Å; L107-V135 HydrophobicContact CG-CG1 4.38Å; L107-M139 HydrophobicContact CB-CE 4.49Å; L107-M139 HydrophobicContact CB-SD 4.14Å; L107-M139 HydrophobicContact CD2-CE 4.05Å; L107-M139 HydrophobicContact CD2-SD 3.78Å; L107-M139 HydrophobicContact CG-SD 4.4Å
108P89.8Confident87.1Confident3 Ų342.7 Ų42.72%0.01921%0.212CC..THydrogen-bonded Turntrans-63-26.4177.8-31.240000116C104 F111 C112 S133 V135 R136C104-P108 VanDerWaalsContact O-CD 3.24Å; C104-P108 WeakPolarHBondContact O-CD 3.15Å; C104-P108 WeakPolarHBondContact O-CG 3.22Å; P108-F111 WeakPolarHBondContact O-CA 3.48Å; P108-F111 PolarHBondContact O-N 3.24Å; P108-C112 PolarHBondContact O-N 3.45Å; P108-S133 WeakPolarHBondContact CB-OG 3.25Å; P108-V135 HydrophobicContact CB-CB 4.37Å; P108-V135 HydrophobicContact CG-CB 4.33Å; P108-V135 HydrophobicContact CG-CG1 4.3Å; P108-R136 HydrophobicContact CG-CB 3.88Å
109K88.8Confident86.1Confident100 Ų10042.3 Ų42.344%0.43522%0.217SC..G310 helixtrans-58-45.8-168.5-62.1179174.4174.20114W40 F44 D105 I106 L107 F111 C112W40-K109 HydrophobicContact CZ2-CB 4.18Å; W40-K109 HydrophobicContact CZ2-CD 4.43Å; F44-K109 WeakPolarHBondContact CE1-O 3.39Å; F44-K109 HydrophobicContact CZ-CB 3.94Å; F44-K109 VanDerWaalsContact CZ-O 3.25Å; F44-K109 WeakPolarHBondContact CZ-O 3.37Å; D105-K109 WeakPolarHBondContact O-CE 3.17Å; I106-K109 PolarHBondContact O-N 2.77Å; L107-K109 VanDerWaalsContact C-N 3.28Å; L107-K109 PolarHBondContact O-N 3.3Å; K109-F111 PolarHBondContact O-N 3.02Å; K109-C112 PolarHBondContact O-SG 3.13Å
110P88.6Confident84.9Confident3 Ų340.1 Ų40.12%0.01922%0.219CC..G310 helixtrans-67.4-16.1176.5-16.231.9000113.8W40 L43 F44 V47 L107W40-P110 HydrophobicContact CH2-CG 3.71Å; W40-P110 HydrophobicContact CZ2-CG 4.01Å; W40-P110 HydrophobicContact CZ3-CG 3.99Å; L43-P110 HydrophobicContact CD2-CB 3.75Å; L43-P110 HydrophobicContact CD2-CG 3.64Å; L43-P110 HydrophobicContact CG-CB 3.74Å; L43-P110 HydrophobicContact CG-CG 4.2Å; F44-P110 HydrophobicContact CD2-CB 3.74Å; F44-P110 HydrophobicContact CD2-CG 4.03Å; F44-P110 HydrophobicContact CE2-CB 3.73Å; F44-P110 HydrophobicContact CE2-CG 3.61Å; F44-P110 HydrophobicContact CG-CB 4.21Å; F44-P110 VanDerWaalsContact CZ-CA 3.5Å; F44-P110 HydrophobicContact CZ-CB 4.22Å; F44-P110 HydrophobicContact CZ-CG 4.2Å; V47-P110 WeakPolarHBondContact CG1-O 3.44Å; L107-P110 WeakPolarHBondContact O-CD 3.28Å
111F90.1Very high82.9Confident0 Ų050 Ų500%026%0.262CS..G310 helixtrans-101.510.7-174.8-60.4-80.9000114.2V26 L43 V47 I61 L65 L107 P108 K109 Q113 L114 E115 V135V26-F111 HydrophobicContact CG2-CE2 4.41Å; V26-F111 HydrophobicContact CG2-CZ 3.85Å; L43-F111 HydrophobicContact CD1-CZ 4.41Å; V47-F111 HydrophobicContact CG1-CD1 3.88Å; V47-F111 HydrophobicContact CG1-CE1 4.41Å; V47-F111 HydrophobicContact CG2-CD1 3.79Å; V47-F111 HydrophobicContact CG2-CE1 3.5Å; V47-F111 VanDerWaalsContact CG2-CE1 3.5Å; V47-F111 HydrophobicContact CG2-CZ 4.21Å; I61-F111 HydrophobicContact CG2-CD1 3.96Å; I61-F111 HydrophobicContact CG2-CE1 3.79Å; L65-F111 HydrophobicContact CD1-CD1 3.72Å; L65-F111 HydrophobicContact CD1-CD2 4.35Å; L65-F111 HydrophobicContact CD1-CE1 3.66Å; L65-F111 HydrophobicContact CD1-CE2 4.31Å; L65-F111 HydrophobicContact CD1-CG 4.08Å; L65-F111 HydrophobicContact CD1-CZ 3.98Å; L65-F111 HydrophobicContact CD2-CE1 4.1Å; L65-F111 HydrophobicContact CD2-CE2 4.06Å; L65-F111 HydrophobicContact CD2-CZ 3.67Å; L65-F111 HydrophobicContact CG-CE1 4.24Å; L65-F111 HydrophobicContact CG-CZ 4.3Å; L107-F111 HydrophobicContact CD1-CE2 3.98Å; L107-F111 VanDerWaalsContact O-CD2 3.23Å; L107-F111 WeakPolarHBondContact O-CD2 3.47Å; P108-F111 WeakPolarHBondContact O-CA 3.48Å; P108-F111 PolarHBondContact O-N 3.24Å; K109-F111 PolarHBondContact O-N 3.02Å; F111-Q113 PolarHBondContact O-N 3.24Å; F111-Q113 VanDerWaalsContact O-N 3.15Å; F111-L114 HydrophobicContact CB-CB 4.25Å; F111-L114 HydrophobicContact CB-CD2 4.36Å; F111-L114 HydrophobicContact CD1-CD2 4.17Å; F111-L114 WeakPolarHBondContact O-CB 3.08Å; F111-L114 PolarHBondContact O-N 2.95Å; F111-E115 PolarHBondContact O-N 3.27Å; F111-V135 HydrophobicContact CB-CG2 3.84Å; F111-V135 HydrophobicContact CG-CG2 4.29Å
112C83.9Confident80.9Confident51 Ų5157.6 Ų57.635%0.34530%0.298SS..Hα-helixtrans-55.4-35.2175.6-65.20000112.9P108 K109 L114 E115 I116P108-C112 PolarHBondContact O-N 3.45Å; K109-C112 PolarHBondContact O-SG 3.13Å; C112-L114 VanDerWaalsContact C-N 3.34Å; C112-L114 PolarHBondContact O-N 3.14Å; C112-E115 PolarHBondContact O-N 2.98Å; C112-I116 WeakPolarHBondContact O-CG1 3.39Å; C112-I116 PolarHBondContact O-N 3.37Å
113Q83.1Confident79Confident53 Ų5356 Ų5625%0.24830%0.295CS..Hα-helixtrans-67.8-33.8177.2-172.858.441.700112.7H48 C51 F111 E115 I116 T117H48-Q113 HydrophobicContact CB-CG 4.37Å; C51-Q113 HydrophobicContact CB-CG 3.92Å; F111-Q113 PolarHBondContact O-N 3.24Å; F111-Q113 VanDerWaalsContact O-N 3.15Å; Q113-E115 VanDerWaalsContact C-N 3.28Å; Q113-E115 PolarHBondContact O-N 3.17Å; Q113-I116 PolarHBondContact O-N 2.82Å; Q113-T117 PolarHBondContact NE2-OG1 3.26Å; Q113-T117 WeakPolarHBondContact O-CB 3.47Å; Q113-T117 PolarHBondContact O-N 3.24Å; Q113-T117 VanDerWaalsContact O-N 3.09Å; Q113-T117 PolarHBondContact O-OG1 3.35Å
114L84.8Confident76.9Confident2 Ų260.1 Ų60.11%0.0132%0.324CS..Hα-helixtrans-60-43.4174.517768.4000110.3P58 I61 H62 L65 F111 C112 T117 L118 V135P58-L114 VanDerWaalsContact CA-CD1 3.49Å; P58-L114 HydrophobicContact CB-CD1 3.77Å; P58-L114 VanDerWaalsContact O-CD1 3.26Å; P58-L114 WeakPolarHBondContact O-CD1 3.49Å; I61-L114 HydrophobicContact CB-CD1 4.22Å; I61-L114 HydrophobicContact CG2-CD1 4.27Å; I61-L114 HydrophobicContact CG2-CD2 3.82Å; H62-L114 HydrophobicContact CB-CD2 4.45Å; L65-L114 HydrophobicContact CD1-CD2 4.13Å; F111-L114 HydrophobicContact CB-CB 4.25Å; F111-L114 HydrophobicContact CB-CD2 4.36Å; F111-L114 HydrophobicContact CD1-CD2 4.17Å; F111-L114 WeakPolarHBondContact O-CB 3.08Å; F111-L114 PolarHBondContact O-N 2.95Å; C112-L114 VanDerWaalsContact C-N 3.34Å; C112-L114 PolarHBondContact O-N 3.14Å; L114-T117 PolarHBondContact O-N 2.79Å; L114-L118 HydrophobicContact CD1-CD1 3.9Å; L114-L118 HydrophobicContact CD1-CG 4.18Å; L114-L118 HydrophobicContact CG-CD1 3.88Å; L114-L118 HydrophobicContact CG-CG 4.45Å; L114-L118 WeakPolarHBondContact O-CB 3.38Å; L114-L118 WeakPolarHBondContact O-CG 3.28Å; L114-L118 PolarHBondContact O-N 3.28Å; L114-V135 HydrophobicContact CD2-CG2 4.47Å
115E78.6Confident74.8Confident17 Ų1767.8 Ų67.88%0.07937%0.365CS..Hα-helixtrans-64.7-46.7-179.6-61.9176.3169.100112F111 C112 Q113 T117 L118 M119 S133 I134F111-E115 PolarHBondContact O-N 3.27Å; C112-E115 PolarHBondContact O-N 2.98Å; Q113-E115 VanDerWaalsContact C-N 3.28Å; Q113-E115 PolarHBondContact O-N 3.17Å; E115-T117 PolarHBondContact O-N 3.07Å; E115-L118 PolarHBondContact O-N 3.44Å; E115-M119 WeakPolarHBondContact O-CB 3.46Å; E115-M119 VanDerWaalsContact O-CG 3.25Å; E115-M119 WeakPolarHBondContact O-CG 3.34Å; E115-M119 PolarHBondContact O-N 2.94Å; E115-S133 WeakPolarHBondContact OE1-CA 3.18Å; E115-S133 WeakPolarHBondContact OE1-CB 3.13Å; E115-S133 PolarHBondContact OE1-OG 2.92Å; E115-I134 HydrophobicContact CG-CB 4.26Å; E115-I134 HydrophobicContact CG-CD1 4.44Å; E115-I134 HydrophobicContact CG-CG1 4.33Å; E115-I134 PolarHBondContact OE1-N 3.18Å
116I80.1Confident72.9Confident102 Ų10273.4 Ų73.452%0.52339%0.387SS..Hα-helixtrans-57.1-39.9175.9-65.3166.7000110.7C112 Q113 G120C112-I116 WeakPolarHBondContact O-CG1 3.39Å; C112-I116 PolarHBondContact O-N 3.37Å; Q113-I116 PolarHBondContact O-N 2.82Å; I116-G120 PolarHBondContact O-N 3.47Å
117T82.1Confident70.9Confident53 Ų5380.9 Ų80.933%0.32542%0.417SS..Hα-helixtrans-74.2-42.3-176.7-49.30000111.6P58 Q113 L114 E115P58-T117 HydrophobicContact CB-CG2 4.27Å; P58-T117 HydrophobicContact CG-CG2 3.59Å; Q113-T117 PolarHBondContact NE2-OG1 3.26Å; Q113-T117 WeakPolarHBondContact O-CB 3.47Å; Q113-T117 PolarHBondContact O-N 3.24Å; Q113-T117 VanDerWaalsContact O-N 3.09Å; Q113-T117 PolarHBondContact O-OG1 3.35Å; L114-T117 PolarHBondContact O-N 2.79Å; E115-T117 PolarHBondContact O-N 3.07Å
118L80.7Confident68.9Low76 Ų7685 Ų8540%0.39845%0.446SS..Hα-helixtrans-73-32.5178.9-71.1176.6000113.4P58 H62 L114 E115 I134P58-L118 HydrophobicContact CB-CD2 3.92Å; P58-L118 HydrophobicContact CB-CG 4.28Å; H62-L118 HydrophobicContact CB-CD1 4.2Å; L114-L118 HydrophobicContact CD1-CD1 3.9Å; L114-L118 HydrophobicContact CD1-CG 4.18Å; L114-L118 HydrophobicContact CG-CD1 3.88Å; L114-L118 HydrophobicContact CG-CG 4.45Å; L114-L118 WeakPolarHBondContact O-CB 3.38Å; L114-L118 WeakPolarHBondContact O-CG 3.28Å; L114-L118 PolarHBondContact O-N 3.28Å; E115-L118 PolarHBondContact O-N 3.44Å; L118-I134 HydrophobicContact CB-CD1 4.17Å; L118-I134 HydrophobicContact CD1-CD1 4.42Å
119M70.7Confident67.3Low115 Ų11589.8 Ų89.857%0.56747%0.472SS*.Hα-helixtrans-82.3-10.2-179-65.9-177.177.400114E115 I134E115-M119 WeakPolarHBondContact O-CB 3.46Å; E115-M119 VanDerWaalsContact O-CG 3.25Å; E115-M119 WeakPolarHBondContact O-CG 3.34Å; E115-M119 PolarHBondContact O-N 2.94Å; M119-I134 HydrophobicContact CG-CD1 3.92Å; M119-I134 HydrophobicContact SD-CD1 4.43Å
120G65.1Low65.8Low39 Ų3988.2 Ų88.240%0.40247%0.47SS..G310 helixtrans65.3179.517900000114.6I116 Q122 G123I116-G120 PolarHBondContact O-N 3.47Å; G120-Q122 PolarHBondContact O-N 2.79Å; G120-G123 PolarHBondContact O-N 3.13Å; G120-G123 VanDerWaalsContact O-N 3.15Å
121K50.1Low64.4Low209 Ų20992.2 Ų92.291%0.90949%0.489SS*.G310 helixtrans-60.6-1.8-174.1-76.7-175.6178.5179.40115.8
122Q49.2Very low63.2Low196 Ų19697.4 Ų97.492%0.91652%0.517SS*.G310 helixtrans-85-11.5175-69.3-168.5-4.900113.6G120G120-Q122 PolarHBondContact O-N 2.79Å
123G50Low63Low34 Ų3495.1 Ų95.135%0.35150%0.501SS..SBendtrans-92.3-9.9-179.600000116.5G120 N125 K126G120-G123 PolarHBondContact O-N 3.13Å; G120-G123 VanDerWaalsContact O-N 3.15Å; G123-N125 VanDerWaalsContact C-N 3.26Å; G123-N125 PolarHBondContact O-N 2.89Å; G123-K126 PolarHBondContact O-N 3.4Å
124S45.8Very low63Low95 Ų9594.8 Ų94.866%0.66450%0.5SS*.THydrogen-bonded Turntrans-71.3-8.3-161.766.60000116.6
125N44.1Very low63.1Low160 Ų16094.7 Ų94.786%0.85650%0.5SS*.THydrogen-bonded Turntrans-109.60.6-177.5-85-0.4000114.9G123G123-N125 VanDerWaalsContact C-N 3.26Å; G123-N125 PolarHBondContact O-N 2.89Å
126K47.1Very low63.6Low182 Ų18295 Ų9579%0.79150%0.5SS*.SBendtrans-98.9121.7171.6-78.6-176.9175.4-179.30108.7G123 S128G123-K126 PolarHBondContact O-N 3.4Å; K126-S128 PolarHBondContact O-N 3.02Å
127K45.7Very low63.9Low209 Ų20996.2 Ų96.291%0.90950%0.502SS*.  trans-49.8109.7163.5-78.7-180174.9176.80106.8N129K127-N129 PolarHBondContact O-N 3.01Å
128S48.5Very low64.2Low87 Ų8794.7 Ų94.761%0.60849%0.492SS*.  trans-62.5101.7-17855.50000108.4K126K126-S128 PolarHBondContact O-N 3.02Å
129N56Low64.7Low103 Ų10391.1 Ų91.155%0.55147%0.473SS*.  trans-74.1135.7172.2-151.38.7000107K127 E131 D132K127-N129 PolarHBondContact O-N 3.01Å; N129-E131 PolarHBondContact O-N 2.93Å; N129-D132 PolarHBondContact O-N 2.69Å
130V57.3Low65.7Low67 Ų6786.2 Ų86.241%0.40645%0.449SS..G310 helixtrans-55.9-25.9-176177.90000111.8D132 S133 R136V130-D132 VanDerWaalsContact C-N 3.26Å; V130-D132 PolarHBondContact O-N 2.77Å; V130-S133 VanDerWaalsContact O-CB 3.27Å; V130-S133 WeakPolarHBondContact O-CB 3.49Å; V130-S133 PolarHBondContact O-N 2.91Å; V130-R136 WeakPolarHBondContact O-CD 3.31Å
131E59.7Low66.8Low87 Ų8786.3 Ų86.341%0.40744%0.44SS..G310 helixtrans-62.1-26.6176.5-65.7-165.8166.700114.8N129 S133 K194N129-E131 PolarHBondContact O-N 2.93Å; E131-S133 VanDerWaalsContact C-N 3.34Å; E131-K194 IonicContact OE2-NZ 3.35Å
132D65.1Low68.7Low109 Ų10977 Ų7758%0.58340%0.401SS*.G310 helixtrans-93.97.5-177.6-66.3-23.8000112.8N129 V130 I134N129-D132 PolarHBondContact O-N 2.69Å; V130-D132 VanDerWaalsContact C-N 3.26Å; V130-D132 PolarHBondContact O-N 2.77Å; D132-I134 PolarHBondContact O-N 2.82Å
133S78.7Confident70.9Confident2 Ų267.6 Ų67.61%0.01436%0.357CS..  trans-61.5130.5-179.6163.50000112.2P108 E115 V130 E131 V135 R136 K137P108-S133 WeakPolarHBondContact CB-OG 3.25Å; E115-S133 WeakPolarHBondContact OE1-CA 3.18Å; E115-S133 WeakPolarHBondContact OE1-CB 3.13Å; E115-S133 PolarHBondContact OE1-OG 2.92Å; V130-S133 VanDerWaalsContact O-CB 3.27Å; V130-S133 WeakPolarHBondContact O-CB 3.49Å; V130-S133 PolarHBondContact O-N 2.91Å; E131-S133 VanDerWaalsContact C-N 3.34Å; S133-V135 VanDerWaalsContact C-N 3.28Å; S133-V135 PolarHBondContact O-N 3.25Å; S133-V135 PolarHBondContact OG-N 3.46Å; S133-R136 PolarHBondContact O-N 2.98Å; S133-R136 PolarHBondContact OG-N 3.19Å; S133-K137 WeakPolarHBondContact O-CB 3.48Å; S133-K137 PolarHBondContact O-N 3.48Å
134I84.3Confident72.8Confident46 Ų4667.5 Ų67.524%0.23635%0.348CS..Hα-helixtrans-62.2-40.6174.8-62.3175.1000110E115 L118 M119 D132 K137 L138E115-I134 HydrophobicContact CG-CB 4.26Å; E115-I134 HydrophobicContact CG-CD1 4.44Å; E115-I134 HydrophobicContact CG-CG1 4.33Å; E115-I134 PolarHBondContact OE1-N 3.18Å; L118-I134 HydrophobicContact CB-CD1 4.17Å; L118-I134 HydrophobicContact CD1-CD1 4.42Å; M119-I134 HydrophobicContact CG-CD1 3.92Å; M119-I134 HydrophobicContact SD-CD1 4.43Å; D132-I134 PolarHBondContact O-N 2.82Å; I134-K137 PolarHBondContact O-N 3.07Å; I134-L138 WeakPolarHBondContact O-CB 3.12Å; I134-L138 PolarHBondContact O-N 3.02Å
135V87.3Confident74.9Confident0 Ų069.6 Ų69.60%035%0.348CS..Hα-helixtrans-65.6-45.3178-179.90000110.4L65 L107 P108 F111 L114 S133 K137 L138 M139L65-V135 HydrophobicContact CD1-CG2 4.18Å; L107-V135 HydrophobicContact CD2-CG1 4.49Å; L107-V135 HydrophobicContact CG-CG1 4.38Å; P108-V135 HydrophobicContact CB-CB 4.37Å; P108-V135 HydrophobicContact CG-CB 4.33Å; P108-V135 HydrophobicContact CG-CG1 4.3Å; F111-V135 HydrophobicContact CB-CG2 3.84Å; F111-V135 HydrophobicContact CG-CG2 4.29Å; L114-V135 HydrophobicContact CD2-CG2 4.47Å; S133-V135 VanDerWaalsContact C-N 3.28Å; S133-V135 PolarHBondContact O-N 3.25Å; S133-V135 PolarHBondContact OG-N 3.46Å; V135-K137 PolarHBondContact O-N 3.19Å; V135-L138 PolarHBondContact O-N 3.22Å; V135-M139 HydrophobicContact CG1-SD 4.4Å; V135-M139 VanDerWaalsContact O-CG 3.29Å; V135-M139 WeakPolarHBondContact O-CG 3.41Å; V135-M139 PolarHBondContact O-N 2.99Å
136R88.8Confident77.1Confident23 Ų2363 Ų639%0.08731%0.314CS..Hα-helixtrans-61-44.7177.1-170.2172.4-176.2-85.9-1.2111.6C104 D105 P108 V130 S133 M139 L140C104-R136 HydrophobicContact CB-CG 4.28Å; D105-R136 IonicContact OD1-NE 3.17Å; P108-R136 HydrophobicContact CG-CB 3.88Å; V130-R136 WeakPolarHBondContact O-CD 3.31Å; S133-R136 PolarHBondContact O-N 2.98Å; S133-R136 PolarHBondContact OG-N 3.19Å; R136-M139 WeakPolarHBondContact O-CB 3.33Å; R136-M139 PolarHBondContact O-N 2.85Å; R136-L140 HydrophobicContact CG-CD1 4.09Å; R136-L140 WeakPolarHBondContact O-CG 3.48Å; R136-L140 PolarHBondContact O-N 3.25Å
137K86.5Confident79.3Confident128 Ų12854.4 Ų54.456%0.55728%0.276SS*.Hα-helixtrans-59.7-48.9176.3-178.1175.4-179.71800111.5S133 I134 V135 M139 L140 D141S133-K137 WeakPolarHBondContact O-CB 3.48Å; S133-K137 PolarHBondContact O-N 3.48Å; I134-K137 PolarHBondContact O-N 3.07Å; V135-K137 PolarHBondContact O-N 3.19Å; K137-M139 VanDerWaalsContact C-N 3.3Å; K137-M139 PolarHBondContact O-N 2.96Å; K137-L140 PolarHBondContact O-N 2.92Å; K137-D141 WeakPolarHBondContact CE-OD2 3.24Å; K137-D141 VanDerWaalsContact CG-OD2 3.32Å; K137-D141 WeakPolarHBondContact CG-OD2 3.32Å; K137-D141 WeakPolarHBondContact O-CB 3.31Å; K137-D141 PolarHBondContact O-N 3.31Å
138L88.3Confident81.5Confident22 Ų2244.6 Ų44.612%0.11523%0.234CC..Hα-helixtrans-55.9-44.9176.7175.164.7000112K66 I69 I134 V135 T142K66-L138 HydrophobicContact CB-CD1 4.33Å; K66-L138 HydrophobicContact CB-CD2 3.93Å; K66-L138 HydrophobicContact CD-CD1 4.21Å; K66-L138 HydrophobicContact CG-CD1 4.02Å; I69-L138 HydrophobicContact CD1-CD2 4.02Å; I69-L138 HydrophobicContact CD1-CG 4.41Å; I134-L138 WeakPolarHBondContact O-CB 3.12Å; I134-L138 PolarHBondContact O-N 3.02Å; V135-L138 PolarHBondContact O-N 3.22Å; L138-T142 VanDerWaalsContact O-CB 3.31Å; L138-T142 WeakPolarHBondContact O-CB 3.31Å; L138-T142 PolarHBondContact O-N 3.29Å; L138-T142 PolarHBondContact O-OG1 3.36Å
139M91.5Very high83.5Confident0 Ų042.7 Ų42.70%022%0.22CC..Hα-helixtrans-58.6-55.8176.2-70.7179.279.800110.8L30 I69 F100 Q103 L107 V135 R136 K137 T142 W143L30-M139 HydrophobicContact CD2-CE 4.22Å; I69-M139 HydrophobicContact CD1-CG 3.71Å; I69-M139 HydrophobicContact CG1-CG 4.26Å; I69-M139 HydrophobicContact CG2-CG 4.2Å; F100-M139 HydrophobicContact CD2-CE 4.28Å; F100-M139 HydrophobicContact CE2-CB 4.11Å; F100-M139 HydrophobicContact CE2-CE 3.79Å; F100-M139 HydrophobicContact CZ-CB 3.76Å; F100-M139 HydrophobicContact CZ-CE 4.38Å; F100-M139 WeakPolarHBondContact CZ-O 3.42Å; Q103-M139 HydrophobicContact CB-CE 4.14Å; L107-M139 HydrophobicContact CB-CE 4.49Å; L107-M139 HydrophobicContact CB-SD 4.14Å; L107-M139 HydrophobicContact CD2-CE 4.05Å; L107-M139 HydrophobicContact CD2-SD 3.78Å; L107-M139 HydrophobicContact CG-SD 4.4Å; V135-M139 HydrophobicContact CG1-SD 4.4Å; V135-M139 VanDerWaalsContact O-CG 3.29Å; V135-M139 WeakPolarHBondContact O-CG 3.41Å; V135-M139 PolarHBondContact O-N 2.99Å; R136-M139 WeakPolarHBondContact O-CB 3.33Å; R136-M139 PolarHBondContact O-N 2.85Å; K137-M139 VanDerWaalsContact C-N 3.3Å; K137-M139 PolarHBondContact O-N 2.96Å; M139-T142 PolarHBondContact O-N 3.04Å; M139-W143 PolarHBondContact O-N 3.08Å
140L90.9Very high85.1Confident12 Ų1243.1 Ų43.16%0.06322%0.223CC..Hα-helixtrans-61.8-45.6-176.1-67.5170.8000112.2W97 F100 R136 K137 T142 W143 N144 L187W97-L140 HydrophobicContact CH2-CD2 4.06Å; F100-L140 HydrophobicContact CE1-CD2 4.3Å; R136-L140 HydrophobicContact CG-CD1 4.09Å; R136-L140 WeakPolarHBondContact O-CG 3.48Å; R136-L140 PolarHBondContact O-N 3.25Å; K137-L140 PolarHBondContact O-N 2.92Å; L140-T142 VanDerWaalsContact C-N 3.35Å; L140-T142 PolarHBondContact O-N 3.31Å; L140-W143 PolarHBondContact O-N 2.99Å; L140-N144 WeakPolarHBondContact O-CB 3.47Å; L140-N144 PolarHBondContact O-N 3.16Å; L140-L187 HydrophobicContact CB-CD2 4.13Å; L140-L187 HydrophobicContact CD2-CD2 3.96Å; L140-L187 VanDerWaalsContact O-CD2 3.28Å; L140-L187 WeakPolarHBondContact O-CD2 3.27Å
141D88.2Confident86.8Confident41 Ų4140.2 Ų40.222%0.21921%0.205CC..Hα-helixtrans-61.6-43.7178.1-72.9-24.4000110.7K137 W143 N144 E145 S189K137-D141 WeakPolarHBondContact CE-OD2 3.24Å; K137-D141 VanDerWaalsContact CG-OD2 3.32Å; K137-D141 WeakPolarHBondContact CG-OD2 3.32Å; K137-D141 WeakPolarHBondContact O-CB 3.31Å; K137-D141 PolarHBondContact O-N 3.31Å; D141-W143 VanDerWaalsContact C-N 3.34Å; D141-W143 PolarHBondContact O-N 3.46Å; D141-N144 WeakPolarHBondContact O-CB 3.43Å; D141-N144 PolarHBondContact O-N 2.85Å; D141-E145 WeakPolarHBondContact O-CG 3.31Å; D141-E145 PolarHBondContact O-N 2.82Å; D141-S189 PolarHBondContact OD1-OG 2.8Å
142T90.4Very high88.3Confident13 Ų1339.1 Ų39.18%0.0820%0.199CC..Hα-helixtrans-64.5-38.2178.4-520000111.9L70 I73 L138 M139 L140 S146L70-T142 HydrophobicContact CB-CG2 4.43Å; L70-T142 HydrophobicContact CD1-CG2 3.67Å; I73-T142 HydrophobicContact CD1-CG2 3.52Å; L138-T142 VanDerWaalsContact O-CB 3.31Å; L138-T142 WeakPolarHBondContact O-CB 3.31Å; L138-T142 PolarHBondContact O-N 3.29Å; L138-T142 PolarHBondContact O-OG1 3.36Å; M139-T142 PolarHBondContact O-N 3.04Å; L140-T142 VanDerWaalsContact C-N 3.35Å; L140-T142 PolarHBondContact O-N 3.31Å; T142-S146 WeakPolarHBondContact O-CB 3.21Å; T142-S146 PolarHBondContact O-N 3.19Å; T142-S146 PolarHBondContact O-OG 3.34Å
143W93.8Very high89.6Confident0 Ų038.2 Ų38.20%019%0.194CC..Hα-helixtrans-66-42.4175.8-177.5-82.4000111.7I73 A76 Y93 E96 W97 F100 M139 L140 D141 I147 F148 L187I73-W143 HydrophobicContact CD1-CB 4.34Å; I73-W143 HydrophobicContact CG1-CE3 4.23Å; A76-W143 HydrophobicContact CB-CH2 4.37Å; A76-W143 HydrophobicContact CB-CZ3 4.05Å; Y93-W143 HydrophobicContact CD2-CZ2 4.22Å; Y93-W143 AromaticContact CE2-CE2 3.91Å; Y93-W143 AromaticContact CE2-CZ2 3.7Å; Y93-W143 HydrophobicContact CE2-CZ2 3.7Å; Y93-W143 AromaticContact CE2-NE1 3.54Å; Y93-W143 AromaticContact CZ-NE1 3.73Å; Y93-W143 PolarHBondContact OH-NE1 3.42Å; Y93-W143 VanDerWaalsContact OH-NE1 3.13Å; E96-W143 HydrophobicContact CB-CH2 3.92Å; W97-W143 HydrophobicContact CB-CZ2 4.03Å; W97-W143 AromaticContact CE3-CD1 3.73Å; W97-W143 AromaticContact CE3-CD2 3.99Å; W97-W143 HydrophobicContact CE3-CD2 3.99Å; W97-W143 AromaticContact CE3-CE2 3.44Å; W97-W143 VanDerWaalsContact CE3-CE2 3.44Å; W97-W143 HydrophobicContact CE3-CG 4.17Å; W97-W143 AromaticContact CE3-CZ2 3.84Å; W97-W143 HydrophobicContact CE3-CZ2 3.84Å; W97-W143 AromaticContact CE3-NE1 3.23Å; W97-W143 AromaticContact CZ3-CD1 3.44Å; W97-W143 VanDerWaalsContact CZ3-CD1 3.44Å; W97-W143 HydrophobicContact CZ3-CD2 4.13Å; W97-W143 AromaticContact CZ3-CE2 3.95Å; W97-W143 AromaticContact CZ3-CG 3.85Å; W97-W143 HydrophobicContact CZ3-CG 3.85Å; W97-W143 AromaticContact CZ3-NE1 3.48Å; F100-W143 HydrophobicContact CB-CE3 3.92Å; F100-W143 HydrophobicContact CB-CH2 4.07Å; F100-W143 HydrophobicContact CB-CZ3 3.56Å; F100-W143 HydrophobicContact CD1-CB 4.38Å; F100-W143 AromaticContact CD1-CD2 3.71Å; F100-W143 HydrophobicContact CD1-CD2 3.71Å; F100-W143 AromaticContact CD1-CE3 3.49Å; F100-W143 HydrophobicContact CD1-CE3 3.49Å; F100-W143 VanDerWaalsContact CD1-CE3 3.49Å; F100-W143 HydrophobicContact CD1-CG 4.09Å; F100-W143 HydrophobicContact CD1-CZ3 4.03Å; F100-W143 AromaticContact CD2-CE3 3.65Å; F100-W143 HydrophobicContact CD2-CE3 3.65Å; F100-W143 AromaticContact CD2-CZ3 3.98Å; F100-W143 HydrophobicContact CD2-CZ3 3.98Å; F100-W143 HydrophobicContact CE1-CB 3.61Å; F100-W143 AromaticContact CE1-CD2 3.86Å; F100-W143 HydrophobicContact CE1-CD2 3.86Å; F100-W143 AromaticContact CE1-CE3 3.84Å; F100-W143 HydrophobicContact CE1-CE3 3.84Å; F100-W143 AromaticContact CE1-CG 3.78Å; F100-W143 HydrophobicContact CE1-CG 3.78Å; F100-W143 AromaticContact CE2-CE3 3.98Å; F100-W143 HydrophobicContact CE2-CE3 3.98Å; F100-W143 HydrophobicContact CG-CD2 4.09Å; F100-W143 AromaticContact CG-CE3 3.38Å; F100-W143 HydrophobicContact CG-CE3 3.38Å; F100-W143 HydrophobicContact CG-CH2 4.4Å; F100-W143 AromaticContact CG-CZ3 3.57Å; F100-W143 HydrophobicContact CG-CZ3 3.57Å; F100-W143 HydrophobicContact CZ-CB 3.7Å; F100-W143 HydrophobicContact CZ-CD2 4.37Å; F100-W143 HydrophobicContact CZ-CE3 4.06Å; F100-W143 HydrophobicContact CZ-CG 4.26Å; M139-W143 PolarHBondContact O-N 3.08Å; L140-W143 PolarHBondContact O-N 2.99Å; D141-W143 VanDerWaalsContact C-N 3.34Å; D141-W143 PolarHBondContact O-N 3.46Å; W143-I147 HydrophobicContact CD2-CD1 4.1Å; W143-I147 HydrophobicContact CE3-CD1 3.94Å; W143-I147 HydrophobicContact CH2-CD1 3.82Å; W143-I147 HydrophobicContact CZ2-CD1 3.98Å; W143-I147 HydrophobicContact CZ3-CD1 3.8Å; W143-I147 PolarHBondContact O-N 2.75Å; W143-F148 PolarHBondContact O-N 3.3Å; W143-L187 HydrophobicContact CB-CD2 4.32Å; W143-L187 HydrophobicContact CG-CD2 4.45Å
144N91.5Very high90.3Very high31 Ų3142.6 Ų42.617%0.16621%0.21CC..Iπ-helixtrans-59.9-53.5177.8-172.927.7000111.3L140 D141 S146 F148 S149 L187L140-N144 WeakPolarHBondContact O-CB 3.47Å; L140-N144 PolarHBondContact O-N 3.16Å; D141-N144 WeakPolarHBondContact O-CB 3.43Å; D141-N144 PolarHBondContact O-N 2.85Å; N144-S146 PolarHBondContact O-N 2.97Å; N144-F148 PolarHBondContact O-N 3.31Å; N144-S149 WeakPolarHBondContact O-CB 3.3Å; N144-S149 PolarHBondContact O-N 3.34Å; N144-S149 PolarHBondContact O-OG 2.96Å; N144-L187 HydrophobicContact CB-CB 4.2Å; N144-L187 HydrophobicContact CB-CD2 4.23Å
145E89.7Confident90.8Very high140 Ų14040.4 Ų40.465%0.65420%0.199SC*.Iπ-helixtrans-63.8-40.9-178.7-70.5178.6179.100112.4D141 S149D141-E145 WeakPolarHBondContact O-CG 3.31Å; D141-E145 PolarHBondContact O-N 2.82Å; E145-S149 PolarHBondContact O-OG 3.36Å; E145-S149 VanDerWaalsContact O-OG 3.11Å
146S90.5Very high91.2Very high20 Ų2041.4 Ų41.414%0.1420%0.203CC..Iπ-helixtrans-81.7-43.4-173.1-55.50000113.2Q77 T142 N144 N150Q77-S146 PolarHBondContact NE2-O 2.79Å; T142-S146 WeakPolarHBondContact O-CB 3.21Å; T142-S146 PolarHBondContact O-N 3.19Å; T142-S146 PolarHBondContact O-OG 3.34Å; N144-S146 PolarHBondContact O-N 2.97Å; S146-N150 PolarHBondContact O-ND2 3.31Å
147I92.5Very high91.4Very high2 Ų244.4 Ų44.41%0.0122%0.221CC..Iπ-helixtrans-114.3-66.8-169.9-56.4179.4000110.2I73 A76 Q77 V80 Y93 W143 S149 N150 I151I73-I147 HydrophobicContact CG2-CD1 4Å; I73-I147 HydrophobicContact CG2-CG1 4.15Å; A76-I147 HydrophobicContact CB-CD1 4.11Å; Q77-I147 HydrophobicContact CB-CD1 4.02Å; Q77-I147 HydrophobicContact CB-CG1 3.76Å; Q77-I147 HydrophobicContact CG-CG1 4.05Å; V80-I147 HydrophobicContact CG1-CG2 4.5Å; Y93-I147 HydrophobicContact CD2-CG2 3.91Å; Y93-I147 HydrophobicContact CE2-CG2 3.85Å; W143-I147 HydrophobicContact CD2-CD1 4.1Å; W143-I147 HydrophobicContact CE3-CD1 3.94Å; W143-I147 HydrophobicContact CH2-CD1 3.82Å; W143-I147 HydrophobicContact CZ2-CD1 3.98Å; W143-I147 HydrophobicContact CZ3-CD1 3.8Å; W143-I147 PolarHBondContact O-N 2.75Å; I147-S149 PolarHBondContact O-N 2.93Å; I147-N150 PolarHBondContact O-N 3.35Å; I147-I151 HydrophobicContact CG2-CD1 3.81Å; I147-I151 WeakPolarHBondContact O-CG1 3.36Å
148F92.4Very high91.8Very high4 Ų438.6 Ų38.62%0.01820%0.197CC..Iπ-helixtrans-63.2-45-163.5-177-110.5000112.9Y93 W143 N144 N150 I151 K152 L155 S183 Y184 L187Y93-F148 HydrophobicContact CE2-CD2 4.38Å; Y93-F148 AromaticContact CZ-CD2 3.87Å; Y93-F148 WeakPolarHBondContact OH-CD2 3.27Å; W143-F148 PolarHBondContact O-N 3.3Å; N144-F148 PolarHBondContact O-N 3.31Å; F148-N150 PolarHBondContact O-N 2.62Å; F148-N150 VanDerWaalsContact O-N 3.1Å; F148-I151 PolarHBondContact O-N 3.4Å; F148-K152 HydrophobicContact CD1-CB 4.21Å; F148-K152 HydrophobicContact CD2-CB 4.28Å; F148-K152 HydrophobicContact CE1-CB 3.92Å; F148-K152 HydrophobicContact CE2-CB 3.98Å; F148-K152 HydrophobicContact CG-CB 4.4Å; F148-K152 HydrophobicContact CZ-CB 3.79Å; F148-K152 WeakPolarHBondContact O-CA 3.43Å; F148-K152 VanDerWaalsContact O-CB 3.28Å; F148-K152 WeakPolarHBondContact O-CB 3.46Å; F148-K152 PolarHBondContact O-N 3.24Å; F148-L155 HydrophobicContact CD2-CD1 4.12Å; F148-L155 HydrophobicContact CE2-CD1 4.28Å; F148-S183 VanDerWaalsContact CE2-CB 3.47Å; F148-Y184 HydrophobicContact CE1-CD1 4.02Å; F148-Y184 HydrophobicContact CE1-CE1 4.04Å; F148-Y184 HydrophobicContact CE1-CG 4.4Å; F148-Y184 HydrophobicContact CE2-CD2 4.48Å; F148-Y184 HydrophobicContact CE2-CE2 4.44Å; F148-Y184 AromaticContact CZ-CD1 3.76Å; F148-Y184 HydrophobicContact CZ-CD1 3.76Å; F148-Y184 AromaticContact CZ-CD2 3.77Å; F148-Y184 HydrophobicContact CZ-CD2 3.77Å; F148-Y184 AromaticContact CZ-CE1 3.76Å; F148-Y184 HydrophobicContact CZ-CE1 3.76Å; F148-Y184 AromaticContact CZ-CE2 3.81Å; F148-Y184 HydrophobicContact CZ-CE2 3.81Å; F148-Y184 AromaticContact CZ-CG 3.77Å; F148-Y184 HydrophobicContact CZ-CG 3.77Å; F148-Y184 AromaticContact CZ-CZ 3.81Å; F148-L187 HydrophobicContact CB-CD1 3.6Å; F148-L187 HydrophobicContact CD1-CD1 3.55Å; F148-L187 HydrophobicContact CD2-CD1 4.09Å; F148-L187 HydrophobicContact CE1-CD1 4.2Å; F148-L187 HydrophobicContact CG-CD1 3.48Å; F148-L187 VanDerWaalsContact CG-CD1 3.48Å
149S90Very high92.1Very high46 Ų4637.6 Ų37.632%0.32219%0.192SC..Hα-helixtrans-53.8-35-177.9640000113.7N144 E145 I147N144-S149 WeakPolarHBondContact O-CB 3.3Å; N144-S149 PolarHBondContact O-N 3.34Å; N144-S149 PolarHBondContact O-OG 2.96Å; E145-S149 PolarHBondContact O-OG 3.36Å; E145-S149 VanDerWaalsContact O-OG 3.11Å; I147-S149 PolarHBondContact O-N 2.93Å
150N89.5Confident92.3Very high113 Ų11338.4 Ų38.460%0.60420%0.196SC*.Hα-helixtrans-81.7-24.6-177.3-65.3-44.6000113.6S146 I147 F148S146-N150 PolarHBondContact O-ND2 3.31Å; I147-N150 PolarHBondContact O-N 3.35Å; F148-N150 PolarHBondContact O-N 2.62Å; F148-N150 VanDerWaalsContact O-N 3.1Å
151I92.7Very high92.5Very high6 Ų643.8 Ų43.83%0.03122%0.219CC..Hα-helixtrans-121.2-3.6-173.467177.4000114.2V80 L81 Y93 I147 F148 N153 R154 L155V80-I151 HydrophobicContact CG1-CD1 3.82Å; L81-I151 HydrophobicContact CD2-CG2 3.76Å; Y93-I151 HydrophobicContact CD2-CD1 3.76Å; Y93-I151 HydrophobicContact CE2-CD1 4.32Å; Y93-I151 HydrophobicContact CG-CD1 4.37Å; I147-I151 HydrophobicContact CG2-CD1 3.81Å; I147-I151 WeakPolarHBondContact O-CG1 3.36Å; F148-I151 PolarHBondContact O-N 3.4Å; I151-N153 VanDerWaalsContact C-N 3.27Å; I151-N153 PolarHBondContact O-N 2.93Å; I151-N153 VanDerWaalsContact O-N 3.13Å; I151-R154 PolarHBondContact O-N 2.95Å; I151-L155 HydrophobicContact CB-CG 4.5Å; I151-L155 HydrophobicContact CD1-CD1 3.83Å; I151-L155 HydrophobicContact CD1-CD2 4.37Å; I151-L155 HydrophobicContact CD1-CG 4.18Å; I151-L155 HydrophobicContact CG1-CD1 3.73Å; I151-L155 HydrophobicContact CG1-CG 4.04Å; I151-L155 WeakPolarHBondContact O-CG 3.37Å; I151-L155 PolarHBondContact O-N 2.98Å
152K92Very high92.8Very high64 Ų6443.6 Ų43.628%0.27822%0.217SC..Hα-helixtrans-50-42.5-173.964.5-178.4-174.9174.20113.8F148 L155 Q156 Y184F148-K152 HydrophobicContact CD1-CB 4.21Å; F148-K152 HydrophobicContact CD2-CB 4.28Å; F148-K152 HydrophobicContact CE1-CB 3.92Å; F148-K152 HydrophobicContact CE2-CB 3.98Å; F148-K152 HydrophobicContact CG-CB 4.4Å; F148-K152 HydrophobicContact CZ-CB 3.79Å; F148-K152 WeakPolarHBondContact O-CA 3.43Å; F148-K152 VanDerWaalsContact O-CB 3.28Å; F148-K152 WeakPolarHBondContact O-CB 3.46Å; F148-K152 PolarHBondContact O-N 3.24Å; K152-L155 PolarHBondContact O-N 3.2Å; K152-Q156 VanDerWaalsContact O-CB 3.31Å; K152-Q156 WeakPolarHBondContact O-CB 3.37Å; K152-Q156 PolarHBondContact O-N 3.02Å; K152-Y184 PolarHBondContact O-OH 3.19Å
153N92.4Very high93Very high90 Ų9043 Ų4348%0.48121%0.213SC..Hα-helixtrans-67.1-43.5-179.4-65.6-15.2000111.3I151 L155 Q156 D157I151-N153 VanDerWaalsContact C-N 3.27Å; I151-N153 PolarHBondContact O-N 2.93Å; I151-N153 VanDerWaalsContact O-N 3.13Å; N153-L155 PolarHBondContact O-N 3.09Å; N153-Q156 PolarHBondContact O-N 2.75Å; N153-D157 WeakPolarHBondContact O-CB 3.33Å; N153-D157 VanDerWaalsContact O-CG 3.23Å; N153-D157 PolarHBondContact O-N 2.9Å
154R93.6Very high93.1Very high93 Ų9346.9 Ų46.935%0.35123%0.232SC..Hα-helixtrans-64-41.2177.1-64.9-179.765.2-170.90.4111.6Q84 D86 L89 I151 S158Q84-R154 PolarHBondContact O-NH2 3.08Å; D86-R154 IonicContact OD1-CZ 3.92Å; D86-R154 VanDerWaalsContact OD1-CZ 3.24Å; D86-R154 IonicContact OD1-NE 3.96Å; D86-R154 PolarHBondContact OD1-NE 3.15Å; D86-R154 IonicContact OD1-NH2 2.7Å; D86-R154 PolarHBondContact OD1-NH2 3.34Å; L89-R154 HydrophobicContact CD2-CB 4.23Å; I151-R154 PolarHBondContact O-N 2.95Å; R154-S158 WeakPolarHBondContact O-CB 3.22Å; R154-S158 PolarHBondContact O-N 3.39Å; R154-S158 VanDerWaalsContact O-N 3.07Å; R154-S158 PolarHBondContact O-OG 3.49Å; R154-S158 VanDerWaalsContact O-OG 3.12Å
155L94.6Very high93.2Very high0 Ų046.2 Ų46.20%023%0.231CC..Hα-helixtrans-64.3-44.2176.1-64.7178.5000111.5L89 L90 Y93 F148 I151 K152 N153 S158 A159 V180L89-L155 HydrophobicContact CG-CD2 4.48Å; L90-L155 HydrophobicContact CB-CD2 4.31Å; L90-L155 HydrophobicContact CD1-CD2 3.89Å; Y93-L155 HydrophobicContact CD1-CD1 3.51Å; Y93-L155 HydrophobicContact CD1-CD2 4.14Å; Y93-L155 HydrophobicContact CD1-CG 4.47Å; Y93-L155 HydrophobicContact CD2-CD1 3.9Å; Y93-L155 HydrophobicContact CE1-CD1 3.66Å; Y93-L155 HydrophobicContact CE2-CD1 4.01Å; Y93-L155 HydrophobicContact CG-CD1 3.64Å; Y93-L155 HydrophobicContact CG-CD2 4.03Å; F148-L155 HydrophobicContact CD2-CD1 4.12Å; F148-L155 HydrophobicContact CE2-CD1 4.28Å; I151-L155 HydrophobicContact CB-CG 4.5Å; I151-L155 HydrophobicContact CD1-CD1 3.83Å; I151-L155 HydrophobicContact CD1-CD2 4.37Å; I151-L155 HydrophobicContact CD1-CG 4.18Å; I151-L155 HydrophobicContact CG1-CD1 3.73Å; I151-L155 HydrophobicContact CG1-CG 4.04Å; I151-L155 WeakPolarHBondContact O-CG 3.37Å; I151-L155 PolarHBondContact O-N 2.98Å; K152-L155 PolarHBondContact O-N 3.2Å; N153-L155 PolarHBondContact O-N 3.09Å; L155-S158 PolarHBondContact O-N 2.97Å; L155-A159 WeakPolarHBondContact O-CB 3.33Å; L155-A159 PolarHBondContact O-N 3.18Å; L155-V180 HydrophobicContact CB-CG1 4.45Å; L155-V180 HydrophobicContact CB-CG2 4.13Å
156Q95.2Very high93.4Very high21 Ų2141.3 Ų41.310%0.09821%0.208CC..Hα-helixtrans-60.7-50.3176.5-178.7-178.8-65.700111.4K152 N153 S158 A159 M160 Y184 N201 A205K152-Q156 VanDerWaalsContact O-CB 3.31Å; K152-Q156 WeakPolarHBondContact O-CB 3.37Å; K152-Q156 PolarHBondContact O-N 3.02Å; N153-Q156 PolarHBondContact O-N 2.75Å; Q156-S158 VanDerWaalsContact C-N 3.31Å; Q156-S158 PolarHBondContact O-N 2.74Å; Q156-A159 WeakPolarHBondContact O-CB 3.22Å; Q156-A159 PolarHBondContact O-N 2.76Å; Q156-A159 VanDerWaalsContact O-N 3.13Å; Q156-M160 HydrophobicContact CG-CE 4.45Å; Q156-M160 WeakPolarHBondContact O-CG 3.32Å; Q156-M160 PolarHBondContact O-N 3.26Å; Q156-Y184 HydrophobicContact CB-CE2 4.25Å; Q156-Y184 PolarHBondContact OE1-OH 3.39Å; Q156-N201 PolarHBondContact OE1-O 3.01Å; Q156-A205 HydrophobicContact CG-CB 4.03Å
157D94.1Very high93.5Very high86 Ų8640.9 Ų40.946%0.4620%0.203SC..Hα-helixtrans-60.4-42.1-179.6-70-18000111.6N153 M160 K161N153-D157 WeakPolarHBondContact O-CB 3.33Å; N153-D157 VanDerWaalsContact O-CG 3.23Å; N153-D157 PolarHBondContact O-N 2.9Å; D157-M160 PolarHBondContact O-N 3Å; D157-K161 WeakPolarHBondContact O-CG 3.11Å; D157-K161 PolarHBondContact O-N 2.99Å
158S94.5Very high93.5Very high7 Ų745.8 Ų45.85%0.04923%0.229CC..Hα-helixtrans-62.9-43.1173.7-68.30000112.7D86 R154 L155 Q156 M160 K161 L162D86-S158 WeakPolarHBondContact CB-OG 3.34Å; R154-S158 WeakPolarHBondContact O-CB 3.22Å; R154-S158 PolarHBondContact O-N 3.39Å; R154-S158 VanDerWaalsContact O-N 3.07Å; R154-S158 PolarHBondContact O-OG 3.49Å; R154-S158 VanDerWaalsContact O-OG 3.12Å; L155-S158 PolarHBondContact O-N 2.97Å; Q156-S158 VanDerWaalsContact C-N 3.31Å; Q156-S158 PolarHBondContact O-N 2.74Å; S158-M160 VanDerWaalsContact C-N 3.34Å; S158-M160 PolarHBondContact O-N 3.46Å; S158-K161 PolarHBondContact O-N 3.39Å; S158-L162 WeakPolarHBondContact O-CG 3.37Å; S158-L162 PolarHBondContact O-N 3.13Å; S158-L162 VanDerWaalsContact O-N 3.12Å
159A95.2Very high93.5Very high0 Ų048.8 Ų48.80%026%0.261CS..Hα-helixtrans-62-41.1175.600000111.7L155 Q156 K161 L162 V163 V177 V180 F202L155-A159 WeakPolarHBondContact O-CB 3.33Å; L155-A159 PolarHBondContact O-N 3.18Å; Q156-A159 WeakPolarHBondContact O-CB 3.22Å; Q156-A159 PolarHBondContact O-N 2.76Å; Q156-A159 VanDerWaalsContact O-N 3.13Å; A159-K161 PolarHBondContact O-N 3.44Å; A159-L162 PolarHBondContact O-N 3.06Å; A159-V163 VanDerWaalsContact O-CG2 3.28Å; A159-V163 WeakPolarHBondContact O-CG2 3.4Å; A159-V163 PolarHBondContact O-N 2.95Å; A159-V177 HydrophobicContact CB-CG2 4.19Å; A159-V180 HydrophobicContact CB-CB 4.38Å; A159-V180 HydrophobicContact CB-CG1 4.42Å; A159-V180 HydrophobicContact CB-CG2 4.29Å; A159-F202 HydrophobicContact CB-CE2 4.44Å
160M95.2Very high93.6Very high17 Ų1752.7 Ų52.78%0.08427%0.274CS..Hα-helixtrans-65.5-36.3176.4-64.7-49.3118.500112.5Q156 D157 S158 V163 H164 F202 A205 Y206Q156-M160 HydrophobicContact CG-CE 4.45Å; Q156-M160 WeakPolarHBondContact O-CG 3.32Å; Q156-M160 PolarHBondContact O-N 3.26Å; D157-M160 PolarHBondContact O-N 3Å; S158-M160 VanDerWaalsContact C-N 3.34Å; S158-M160 PolarHBondContact O-N 3.46Å; M160-V163 PolarHBondContact O-N 2.88Å; M160-H164 WeakPolarHBondContact O-CB 3.34Å; M160-H164 PolarHBondContact O-N 2.92Å; M160-F202 HydrophobicContact CE-CD2 3.95Å; M160-F202 HydrophobicContact CE-CE1 4.43Å; M160-F202 HydrophobicContact CE-CE2 3.57Å; M160-F202 HydrophobicContact CE-CZ 3.85Å; M160-A205 HydrophobicContact CG-CB 4.35Å; M160-Y206 HydrophobicContact CE-CD2 4.12Å; M160-Y206 HydrophobicContact SD-CD2 4.16Å; M160-Y206 HydrophobicContact SD-CG 4.45Å
161K94.3Very high93.6Very high126 Ų12652.3 Ų52.355%0.54829%0.286SS..Hα-helixtrans-62.8-40.7173.2-71.4172-170.41700112D157 S158 A159 H164 A165D157-K161 WeakPolarHBondContact O-CG 3.11Å; D157-K161 PolarHBondContact O-N 2.99Å; S158-K161 PolarHBondContact O-N 3.39Å; A159-K161 PolarHBondContact O-N 3.44Å; K161-H164 WeakPolarHBondContact O-CB 3.18Å; K161-H164 PolarHBondContact O-N 3.36Å; K161-A165 PolarHBondContact O-N 2.94Å
162L95.2Very high93.6Very high36 Ų3653.8 Ų53.819%0.18829%0.293CS..Hα-helixtrans-63.9-44.7175.8-67175000111.6L90 S158 A159 H164 A165 E166 F172 L176 V177L90-L162 HydrophobicContact CD2-CD1 3.73Å; S158-L162 WeakPolarHBondContact O-CG 3.37Å; S158-L162 PolarHBondContact O-N 3.13Å; S158-L162 VanDerWaalsContact O-N 3.12Å; A159-L162 PolarHBondContact O-N 3.06Å; L162-H164 VanDerWaalsContact C-N 3.3Å; L162-H164 PolarHBondContact O-N 3.41Å; L162-A165 PolarHBondContact O-N 3.12Å; L162-E166 PolarHBondContact O-N 3.38Å; L162-F172 HydrophobicContact CB-CD1 3.98Å; L162-F172 HydrophobicContact CB-CD2 3.99Å; L162-F172 HydrophobicContact CB-CE1 3.92Å; L162-F172 HydrophobicContact CB-CE2 3.98Å; L162-F172 HydrophobicContact CB-CG 4.03Å; L162-F172 HydrophobicContact CB-CZ 3.95Å; L162-F172 HydrophobicContact CD1-CD2 4Å; L162-F172 HydrophobicContact CD1-CE2 4.31Å; L162-F172 HydrophobicContact CD2-CB 4.09Å; L162-F172 HydrophobicContact CD2-CD2 4.41Å; L162-F172 HydrophobicContact CD2-CG 4.14Å; L162-F172 HydrophobicContact CG-CD2 4.37Å; L162-F172 HydrophobicContact CG-CG 4.47Å; L162-F172 WeakPolarHBondContact O-CD1 3.46Å; L162-F172 WeakPolarHBondContact O-CE1 3.45Å; L162-L176 HydrophobicContact CD1-CB 3.76Å; L162-L176 HydrophobicContact CD1-CD1 3.78Å; L162-L176 HydrophobicContact CD1-CG 4.44Å; L162-V177 HydrophobicContact CB-CG2 4.23Å; L162-V177 HydrophobicContact CD1-CG2 4.4Å
163V95.1Very high93.6Very high0 Ų055 Ų550%030%0.302CS..Hα-helixtrans-61.2-41175.9177.90000111A159 M160 E166 R167 V177 Y206 Y248A159-V163 VanDerWaalsContact O-CG2 3.28Å; A159-V163 WeakPolarHBondContact O-CG2 3.4Å; A159-V163 PolarHBondContact O-N 2.95Å; M160-V163 PolarHBondContact O-N 2.88Å; V163-E166 PolarHBondContact O-N 3.48Å; V163-R167 WeakPolarHBondContact O-CG 3.48Å; V163-R167 PolarHBondContact O-N 3.39Å; V163-V177 HydrophobicContact CG2-CG1 4.06Å; V163-V177 HydrophobicContact CG2-CG2 3.96Å; V163-Y206 HydrophobicContact CG1-CE2 3.93Å; V163-Y206 HydrophobicContact CG2-CE2 3.97Å; V163-Y248 HydrophobicContact CG2-CD2 4.5Å
164H94.5Very high93.6Very high82 Ų8251.6 Ų51.638%0.3829%0.285SS..Hα-helixtrans-60.9-44.7174.4-178.387.2000112.4M160 K161 L162 R167 L168 F213M160-H164 WeakPolarHBondContact O-CB 3.34Å; M160-H164 PolarHBondContact O-N 2.92Å; K161-H164 WeakPolarHBondContact O-CB 3.18Å; K161-H164 PolarHBondContact O-N 3.36Å; L162-H164 VanDerWaalsContact C-N 3.3Å; L162-H164 PolarHBondContact O-N 3.41Å; H164-R167 WeakPolarHBondContact O-CB 3.34Å; H164-R167 PolarHBondContact O-N 3.38Å; H164-L168 PolarHBondContact O-N 3.48Å; H164-F213 AromaticContact CE1-CD2 3.59Å; H164-F213 AromaticContact CE1-CE2 3.93Å; H164-F213 AromaticContact ND1-CD2 3.56Å
165A93.5Very high93.6Very high18 Ų1849.8 Ų49.815%0.14928%0.281CS..Hα-helixtrans-64-39.4178.200000112.5K161 L162 R167 L168 G169 E170K161-A165 PolarHBondContact O-N 2.94Å; L162-A165 PolarHBondContact O-N 3.12Å; A165-R167 VanDerWaalsContact C-N 3.33Å; A165-R167 PolarHBondContact O-N 3.32Å; A165-L168 CarbonylContact O-C 3.56Å; A165-L168 WeakPolarHBondContact O-CA 3.38Å; A165-L168 WeakPolarHBondContact O-CB 3.22Å; A165-L168 PolarHBondContact O-N 3.21Å; A165-G169 PolarHBondContact O-N 3.43Å; A165-E170 HydrophobicContact CB-CB 4.06Å; A165-E170 PolarHBondContact O-N 2.94Å
166E94.5Very high93.6Very high36 Ų3650.4 Ų50.417%0.16828%0.284CS..Hα-helixtrans-66.5-31.8175.9-176.7-164.6-126.500112.9L162 V163 L168 G169 E170 F172 R244 R247 Y248L162-E166 PolarHBondContact O-N 3.38Å; V163-E166 PolarHBondContact O-N 3.48Å; E166-L168 PolarHBondContact O-N 2.88Å; E166-G169 PolarHBondContact O-N 3.13Å; E166-E170 WeakPolarHBondContact CA-O 3.47Å; E166-F172 HydrophobicContact CB-CD1 3.92Å; E166-F172 HydrophobicContact CB-CE1 3.52Å; E166-F172 HydrophobicContact CG-CE1 4.19Å; E166-R244 WeakPolarHBondContact OE2-CD 3.46Å; E166-R244 IonicContact OE2-CZ 2.8Å; E166-R244 IonicContact OE2-NE 3.81Å; E166-R244 PolarHBondContact OE2-NE 3Å; E166-R244 IonicContact OE2-NH2 3.08Å; E166-R247 IonicContact OE1-NH1 3.99Å; E166-R247 PolarHBondContact OE1-NH1 2.93Å; E166-Y248 PolarHBondContact OE1-OH 3.1Å; E166-Y248 WeakPolarHBondContact OE2-CE2 3.14Å
167R93.5Very high93.6Very high12 Ų1249.4 Ų49.45%0.04528%0.28CS..Hα-helixtrans-63.4-25.1170.9-70.6175.3175.5132.36.9113V163 H164 A165 T210 F213 E241V163-R167 WeakPolarHBondContact O-CG 3.48Å; V163-R167 PolarHBondContact O-N 3.39Å; H164-R167 WeakPolarHBondContact O-CB 3.34Å; H164-R167 PolarHBondContact O-N 3.38Å; A165-R167 VanDerWaalsContact C-N 3.33Å; A165-R167 PolarHBondContact O-N 3.32Å; R167-T210 PolarHBondContact NH2-OG1 2.99Å; R167-F213 HydrophobicContact CB-CE1 3.94Å; R167-F213 HydrophobicContact CB-CE2 3.99Å; R167-F213 HydrophobicContact CB-CZ 3.61Å; R167-F213 HydrophobicContact CG-CE1 4.42Å; R167-E241 IonicContact CZ-OE1 3.06Å; R167-E241 IonicContact CZ-OE2 2.98Å; R167-E241 IonicContact NE-OE1 2.79Å; R167-E241 PolarHBondContact NE-OE1 2.87Å; R167-E241 IonicContact NE-OE2 2.81Å; R167-E241 IonicContact NH2-OE1 3.59Å; R167-E241 IonicContact NH2-OE2 3.44Å; R167-E241 PolarHBondContact NH2-OE2 2.88Å
168L92.5Very high93.7Very high105 Ų10546.3 Ų46.355%0.5526%0.263SS..THydrogen-bonded Turntrans-89.9-2.8174.1-61.9174.7000113.2H164 A165 E166 F213H164-L168 PolarHBondContact O-N 3.48Å; A165-L168 CarbonylContact O-C 3.56Å; A165-L168 WeakPolarHBondContact O-CA 3.38Å; A165-L168 WeakPolarHBondContact O-CB 3.22Å; A165-L168 PolarHBondContact O-N 3.21Å; E166-L168 PolarHBondContact O-N 2.88Å; L168-F213 HydrophobicContact CD2-CE2 4.05Å; L168-F213 HydrophobicContact CD2-CZ 4.25Å; L168-F213 HydrophobicContact CG-CE2 4.38Å
169G91Very high93.6Very high67 Ų6746 Ų4669%0.69126%0.261SS*.THydrogen-bonded Turntrans102.75.4175.900000115.3A165 E166A165-G169 PolarHBondContact O-N 3.43Å; E166-G169 PolarHBondContact O-N 3.13Å
170E91.7Very high93.6Very high128 Ų12846 Ų4660%0.59826%0.261SS*.  trans-83.5127.4178.1-62.4-173.7-175.400111.9A165 E166A165-E170 HydrophobicContact CB-CB 4.06Å; A165-E170 PolarHBondContact O-N 2.94Å; E166-E170 WeakPolarHBondContact CA-O 3.47Å
171A89.9Confident93.5Very high104 Ų10446.5 Ų46.586%0.8626%0.262SS*.  trans-82.3139176.900000111.4
172F92.4Very high93.4Very high38 Ų3842.6 Ų42.617%0.16725%0.245CC..  trans-140.4168.2172.971.4-94.5000110.9L162 E166 S174 V177 Y248L162-F172 HydrophobicContact CB-CD1 3.98Å; L162-F172 HydrophobicContact CB-CD2 3.99Å; L162-F172 HydrophobicContact CB-CE1 3.92Å; L162-F172 HydrophobicContact CB-CE2 3.98Å; L162-F172 HydrophobicContact CB-CG 4.03Å; L162-F172 HydrophobicContact CB-CZ 3.95Å; L162-F172 HydrophobicContact CD1-CD2 4Å; L162-F172 HydrophobicContact CD1-CE2 4.31Å; L162-F172 HydrophobicContact CD2-CB 4.09Å; L162-F172 HydrophobicContact CD2-CD2 4.41Å; L162-F172 HydrophobicContact CD2-CG 4.14Å; L162-F172 HydrophobicContact CG-CD2 4.37Å; L162-F172 HydrophobicContact CG-CG 4.47Å; L162-F172 WeakPolarHBondContact O-CD1 3.46Å; L162-F172 WeakPolarHBondContact O-CE1 3.45Å; E166-F172 HydrophobicContact CB-CD1 3.92Å; E166-F172 HydrophobicContact CB-CE1 3.52Å; E166-F172 HydrophobicContact CG-CE1 4.19Å; F172-S174 PolarHBondContact O-N 3.49Å; F172-V177 HydrophobicContact CE2-CB 4.3Å; F172-V177 HydrophobicContact CE2-CG2 3.49Å; F172-V177 VanDerWaalsContact CE2-CG2 3.49Å; F172-V177 HydrophobicContact CZ-CG2 3.66Å; F172-Y248 HydrophobicContact CZ-CE1 4.35Å; F172-Y248 HydrophobicContact CZ-CE2 4.19Å; F172-Y248 AromaticContact CZ-CZ 3.71Å; F172-Y248 WeakPolarHBondContact CZ-OH 3.4Å
173D92.3Very high93.3Very high89 Ų8940.9 Ų40.948%0.47624%0.236SC..  trans-72.7108.6174.4179.46.7000111.1Q175 L176D173-Q175 PolarHBondContact O-N 3.12Å; D173-Q175 WeakPolarHBondContact OD1-CB 3.23Å; D173-Q175 WeakPolarHBondContact OD1-CG 3.46Å; D173-Q175 PolarHBondContact OD1-N 3.07Å; D173-L176 HydrophobicContact CB-CD1 4.41Å; D173-L176 HydrophobicContact CB-CG 4.28Å; D173-L176 WeakPolarHBondContact O-CB 3.21Å; D173-L176 WeakPolarHBondContact O-CG 3.47Å; D173-L176 PolarHBondContact O-N 3.07Å
174S93Very high93.2Very high19 Ų1941 Ų4113%0.13324%0.237CC..THydrogen-bonded Turntrans-53.2-26.1178.241.10000115.6F172 L176 V177 I178 R247F172-S174 PolarHBondContact O-N 3.49Å; S174-L176 PolarHBondContact O-N 3.46Å; S174-V177 PolarHBondContact O-N 2.85Å; S174-V177 VanDerWaalsContact O-N 3.16Å; S174-I178 WeakPolarHBondContact O-CB 3.39Å; S174-I178 VanDerWaalsContact O-CG1 3.3Å; S174-I178 WeakPolarHBondContact O-CG1 3.46Å; S174-I178 PolarHBondContact O-N 3.34Å; S174-R247 VanDerWaalsContact CB-NE 3.32Å; S174-R247 PolarHBondContact OG-NH2 2.82Å
175Q93.7Very high93Very high54 Ų5437.5 Ų37.525%0.25222%0.221SC..Hα-helixtrans-61.2-24.7178.6-65.7-64-57.700112D173 G179D173-Q175 PolarHBondContact O-N 3.12Å; D173-Q175 WeakPolarHBondContact OD1-CB 3.23Å; D173-Q175 WeakPolarHBondContact OD1-CG 3.46Å; D173-Q175 PolarHBondContact OD1-N 3.07Å; Q175-G179 PolarHBondContact O-N 3.33Å
176L94.9Very high92.8Very high14 Ų1437.6 Ų37.67%0.07322%0.219CC..Hα-helixtrans-65.3-40177-60.5179.3000112.4L90 K91 I94 L162 D173 S174 V180L90-L176 HydrophobicContact CD2-CB 4.06Å; L90-L176 HydrophobicContact CG-CB 4.37Å; L90-L176 HydrophobicContact CG-CD2 4.35Å; K91-L176 HydrophobicContact CG-CD1 4.34Å; K91-L176 HydrophobicContact CG-CD2 3.92Å; I94-L176 HydrophobicContact CB-CD2 4.25Å; I94-L176 HydrophobicContact CG1-CD2 4.17Å; I94-L176 HydrophobicContact CG2-CD2 4.41Å; L162-L176 HydrophobicContact CD1-CB 3.76Å; L162-L176 HydrophobicContact CD1-CD1 3.78Å; L162-L176 HydrophobicContact CD1-CG 4.44Å; D173-L176 HydrophobicContact CB-CD1 4.41Å; D173-L176 HydrophobicContact CB-CG 4.28Å; D173-L176 WeakPolarHBondContact O-CB 3.21Å; D173-L176 WeakPolarHBondContact O-CG 3.47Å; D173-L176 PolarHBondContact O-N 3.07Å; S174-L176 PolarHBondContact O-N 3.46Å; L176-V180 WeakPolarHBondContact O-CG2 3.39Å
177V95.3Very high92.4Very high0 Ų036 Ų360%021%0.212CC..Hα-helixtrans-82.7-42.7177.7176.20000110.5A159 L162 V163 F172 S174 G179 V180 R181 F202 Y248A159-V177 HydrophobicContact CB-CG2 4.19Å; L162-V177 HydrophobicContact CB-CG2 4.23Å; L162-V177 HydrophobicContact CD1-CG2 4.4Å; V163-V177 HydrophobicContact CG2-CG1 4.06Å; V163-V177 HydrophobicContact CG2-CG2 3.96Å; F172-V177 HydrophobicContact CE2-CB 4.3Å; F172-V177 HydrophobicContact CE2-CG2 3.49Å; F172-V177 VanDerWaalsContact CE2-CG2 3.49Å; F172-V177 HydrophobicContact CZ-CG2 3.66Å; S174-V177 PolarHBondContact O-N 2.85Å; S174-V177 VanDerWaalsContact O-N 3.16Å; V177-G179 PolarHBondContact O-N 2.96Å; V177-V180 PolarHBondContact O-N 3.18Å; V177-R181 PolarHBondContact O-N 2.83Å; V177-F202 HydrophobicContact CG1-CZ 3.93Å; V177-Y248 HydrophobicContact CB-CD1 3.98Å; V177-Y248 HydrophobicContact CB-CE1 4.21Å; V177-Y248 HydrophobicContact CB-CG 4.44Å; V177-Y248 HydrophobicContact CG1-CD1 3.78Å; V177-Y248 HydrophobicContact CG1-CD2 4.4Å; V177-Y248 HydrophobicContact CG1-CE1 4.43Å; V177-Y248 HydrophobicContact CG1-CG 3.78Å
178I94.7Very high91.8Very high20 Ų2036.3 Ų36.310%0.10322%0.216CC..Hα-helixtrans-57.9-47.9178.7-69168.4000110.8S174 V180 R181 E182 Y248S174-I178 WeakPolarHBondContact O-CB 3.39Å; S174-I178 VanDerWaalsContact O-CG1 3.3Å; S174-I178 WeakPolarHBondContact O-CG1 3.46Å; S174-I178 PolarHBondContact O-N 3.34Å; I178-V180 VanDerWaalsContact C-N 3.33Å; I178-V180 PolarHBondContact O-N 2.91Å; I178-R181 WeakPolarHBondContact O-CB 3.18Å; I178-R181 PolarHBondContact O-N 3.36Å; I178-E182 HydrophobicContact CG2-CG 4.2Å; I178-E182 WeakPolarHBondContact O-CG 3.36Å; I178-E182 PolarHBondContact O-N 3.5Å; I178-Y248 HydrophobicContact CG1-CD1 4.08Å
179G93.3Very high90.8Very high1 Ų134.3 Ų34.31%0.0121%0.21CC..Hα-helixtrans-70.3-27-177.300000113.6Q175 V177 S183Q175-G179 PolarHBondContact O-N 3.33Å; V177-G179 PolarHBondContact O-N 2.96Å; G179-S183 WeakPolarHBondContact O-CB 3.25Å; G179-S183 PolarHBondContact O-N 3.36Å; G179-S183 PolarHBondContact O-OG 3.33Å
180V94.9Very high90Very high0 Ų033.1 Ų33.10%019%0.188CC..Hα-helixtrans-67.5-46.3169.9176.10000110.2L90 I94 L155 A159 L176 V177 I178 E182 S183 Y184 F202L90-V180 HydrophobicContact CD1-CG2 3.47Å; L90-V180 VanDerWaalsContact CD1-CG2 3.47Å; I94-V180 HydrophobicContact CD1-CG2 4.15Å; L155-V180 HydrophobicContact CB-CG1 4.45Å; L155-V180 HydrophobicContact CB-CG2 4.13Å; A159-V180 HydrophobicContact CB-CB 4.38Å; A159-V180 HydrophobicContact CB-CG1 4.42Å; A159-V180 HydrophobicContact CB-CG2 4.29Å; L176-V180 WeakPolarHBondContact O-CG2 3.39Å; V177-V180 PolarHBondContact O-N 3.18Å; I178-V180 VanDerWaalsContact C-N 3.33Å; I178-V180 PolarHBondContact O-N 2.91Å; V180-E182 PolarHBondContact O-N 3.44Å; V180-S183 WeakPolarHBondContact O-CB 3.32Å; V180-S183 PolarHBondContact O-N 3.49Å; V180-Y184 HydrophobicContact CG1-CD2 3.97Å; V180-Y184 HydrophobicContact CG1-CE2 3.95Å; V180-Y184 WeakPolarHBondContact O-CD2 3.08Å; V180-Y184 PolarHBondContact O-N 2.82Å; V180-Y184 VanDerWaalsContact O-N 3.08Å; V180-F202 HydrophobicContact CB-CE2 4.22Å; V180-F202 HydrophobicContact CG1-CD2 3.84Å; V180-F202 HydrophobicContact CG1-CE2 3.83Å
181R94Very high89Confident27 Ų2732.5 Ų32.510%0.10220%0.195CC..Hα-helixtrans-58.1-47.6174.3177.6-94.7-60.6-175.65.3111.6V177 I178 S183 Y184 V185 Y198 F202 Y248 E250V177-R181 PolarHBondContact O-N 2.83Å; I178-R181 WeakPolarHBondContact O-CB 3.18Å; I178-R181 PolarHBondContact O-N 3.36Å; R181-S183 VanDerWaalsContact C-N 3.25Å; R181-S183 PolarHBondContact O-N 3.13Å; R181-Y184 PolarHBondContact O-N 3.48Å; R181-Y184 VanDerWaalsContact O-N 3.15Å; R181-V185 HydrophobicContact CG-CG2 4.4Å; R181-V185 WeakPolarHBondContact O-CG2 3.14Å; R181-V185 PolarHBondContact O-N 2.89Å; R181-Y198 HydrophobicContact CG-CD2 4.17Å; R181-Y198 HydrophobicContact CG-CE2 3.62Å; R181-F202 HydrophobicContact CB-CD1 4.26Å; R181-F202 HydrophobicContact CB-CE1 3.82Å; R181-F202 HydrophobicContact CB-CE2 4.22Å; R181-F202 HydrophobicContact CB-CZ 3.8Å; R181-F202 HydrophobicContact CG-CD1 4.31Å; R181-F202 HydrophobicContact CG-CE1 4.08Å; R181-Y248 WeakPolarHBondContact CG-O 3.39Å; R181-Y248 PolarHBondContact NE-O 2.87Å; R181-E250 IonicContact CZ-OE2 3.76Å; R181-E250 IonicContact NH1-OE1 2.8Å; R181-E250 IonicContact NH1-OE2 3.36Å; R181-E250 PolarHBondContact NH1-OE2 3.42Å
182E92.3Very high88.4Confident45 Ų4536.5 Ų36.521%0.2120%0.196CC..Hα-helixtrans-61-34.6177.3-73.9175.4163.300112.4I178 V180 V185 N186I178-E182 HydrophobicContact CG2-CG 4.2Å; I178-E182 WeakPolarHBondContact O-CG 3.36Å; I178-E182 PolarHBondContact O-N 3.5Å; V180-E182 PolarHBondContact O-N 3.44Å; E182-V185 PolarHBondContact O-N 3.43Å; E182-N186 VanDerWaalsContact O-CB 3.31Å; E182-N186 WeakPolarHBondContact O-CB 3.42Å; E182-N186 PolarHBondContact O-N 3.09Å; E182-N186 PolarHBondContact O-ND2 3.39Å
183S92.6Very high87.9Confident0 Ų037.2 Ų37.20%020%0.202CC..Hα-helixtrans-63.1-48.6173.9-59.20000110.5Y93 F148 G179 V180 R181 V185 L187Y93-S183 WeakPolarHBondContact CE1-OG 3.34Å; Y93-S183 WeakPolarHBondContact OH-CB 3.47Å; Y93-S183 PolarHBondContact OH-OG 2.95Å; F148-S183 VanDerWaalsContact CE2-CB 3.47Å; G179-S183 WeakPolarHBondContact O-CB 3.25Å; G179-S183 PolarHBondContact O-N 3.36Å; G179-S183 PolarHBondContact O-OG 3.33Å; V180-S183 WeakPolarHBondContact O-CB 3.32Å; V180-S183 PolarHBondContact O-N 3.49Å; R181-S183 VanDerWaalsContact C-N 3.25Å; R181-S183 PolarHBondContact O-N 3.13Å; S183-V185 VanDerWaalsContact C-N 3.34Å; S183-V185 PolarHBondContact O-N 2.96Å; S183-L187 WeakPolarHBondContact O-CB 3.33Å; S183-L187 WeakPolarHBondContact O-CD1 3.46Å; S183-L187 WeakPolarHBondContact O-CG 3.32Å; S183-L187 PolarHBondContact O-N 3.39Å
184Y92.6Very high87.3Confident1 Ų138 Ų380%0.00420%0.201CC..Hα-helixtrans-61.3-38177.1-86.7-69.2000113.8F148 K152 Q156 V180 R181 I197 N201 F202F148-Y184 HydrophobicContact CE1-CD1 4.02Å; F148-Y184 HydrophobicContact CE1-CE1 4.04Å; F148-Y184 HydrophobicContact CE1-CG 4.4Å; F148-Y184 HydrophobicContact CE2-CD2 4.48Å; F148-Y184 HydrophobicContact CE2-CE2 4.44Å; F148-Y184 AromaticContact CZ-CD1 3.76Å; F148-Y184 HydrophobicContact CZ-CD1 3.76Å; F148-Y184 AromaticContact CZ-CD2 3.77Å; F148-Y184 HydrophobicContact CZ-CD2 3.77Å; F148-Y184 AromaticContact CZ-CE1 3.76Å; F148-Y184 HydrophobicContact CZ-CE1 3.76Å; F148-Y184 AromaticContact CZ-CE2 3.81Å; F148-Y184 HydrophobicContact CZ-CE2 3.81Å; F148-Y184 AromaticContact CZ-CG 3.77Å; F148-Y184 HydrophobicContact CZ-CG 3.77Å; F148-Y184 AromaticContact CZ-CZ 3.81Å; K152-Y184 PolarHBondContact O-OH 3.19Å; Q156-Y184 HydrophobicContact CB-CE2 4.25Å; Q156-Y184 PolarHBondContact OE1-OH 3.39Å; V180-Y184 HydrophobicContact CG1-CD2 3.97Å; V180-Y184 HydrophobicContact CG1-CE2 3.95Å; V180-Y184 WeakPolarHBondContact O-CD2 3.08Å; V180-Y184 PolarHBondContact O-N 2.82Å; V180-Y184 VanDerWaalsContact O-N 3.08Å; R181-Y184 PolarHBondContact O-N 3.48Å; R181-Y184 VanDerWaalsContact O-N 3.15Å; Y184-I197 HydrophobicContact CD1-CG2 3.98Å; Y184-I197 HydrophobicContact CE1-CG2 4.33Å; Y184-N201 HydrophobicContact CD1-CB 4.11Å; Y184-N201 HydrophobicContact CE1-CB 3.45Å; Y184-N201 VanDerWaalsContact CE1-CB 3.45Å; Y184-F202 HydrophobicContact CD2-CB 3.6Å; Y184-F202 AromaticContact CD2-CD2 3.87Å; Y184-F202 HydrophobicContact CD2-CD2 3.87Å; Y184-F202 HydrophobicContact CD2-CG 4.11Å; Y184-F202 HydrophobicContact CE2-CB 3.99Å; Y184-F202 HydrophobicContact CE2-CD2 4.14Å; Y184-F202 HydrophobicContact CG-CB 3.92Å
185V90.5Very high87.1Confident9 Ų938.4 Ų38.46%0.05520%0.202CC..Hα-helixtrans-74.9-45.21801710000111.9R181 E182 S183 L195 Y198 E250R181-V185 HydrophobicContact CG-CG2 4.4Å; R181-V185 WeakPolarHBondContact O-CG2 3.14Å; R181-V185 PolarHBondContact O-N 2.89Å; E182-V185 PolarHBondContact O-N 3.43Å; S183-V185 VanDerWaalsContact C-N 3.34Å; S183-V185 PolarHBondContact O-N 2.96Å; V185-L195 HydrophobicContact CG1-CD2 3.92Å; V185-L195 HydrophobicContact CG2-CD2 4.11Å; V185-Y198 HydrophobicContact CG2-CD1 4.41Å; V185-Y198 HydrophobicContact CG2-CD2 3.74Å; V185-Y198 HydrophobicContact CG2-CE2 4.36Å; V185-Y198 HydrophobicContact CG2-CG 3.78Å; V185-E250 HydrophobicContact CG2-CB 4.28Å; V185-E250 HydrophobicContact CG2-CG 4.16Å
186N88.4Confident86.8Confident20 Ų2039.5 Ų39.511%0.10721%0.207CC..Hα-helixtrans-89.3-20.6-171.6-62.5-68.3000113.9W97 F101 E182 C188 R252W97-N186 HydrophobicContact CZ2-CB 4.45Å; F101-N186 HydrophobicContact CE2-CB 3.8Å; F101-N186 WeakPolarHBondContact CE2-ND2 3.33Å; F101-N186 HydrophobicContact CZ-CB 4.46Å; F101-N186 WeakPolarHBondContact CZ-ND2 3.41Å; E182-N186 VanDerWaalsContact O-CB 3.31Å; E182-N186 WeakPolarHBondContact O-CB 3.42Å; E182-N186 PolarHBondContact O-N 3.09Å; E182-N186 PolarHBondContact O-ND2 3.39Å; N186-C188 VanDerWaalsContact C-N 3.29Å; N186-R252 PolarHBondContact OD1-NH2 2.57Å
187L88Confident86.4Confident4 Ų441.4 Ų41.42%0.02122%0.216CC..THydrogen-bonded Turntrans-90.39.4178.1-59.2171.9000112.9W97 L140 W143 N144 F148 S183 S189W97-L187 HydrophobicContact CH2-CD1 4.04Å; W97-L187 HydrophobicContact CH2-CD2 3.63Å; W97-L187 HydrophobicContact CH2-CG 3.72Å; W97-L187 HydrophobicContact CZ3-CD1 4.09Å; W97-L187 HydrophobicContact CZ3-CD2 3.79Å; W97-L187 HydrophobicContact CZ3-CG 4.14Å; L140-L187 HydrophobicContact CB-CD2 4.13Å; L140-L187 HydrophobicContact CD2-CD2 3.96Å; L140-L187 VanDerWaalsContact O-CD2 3.28Å; L140-L187 WeakPolarHBondContact O-CD2 3.27Å; W143-L187 HydrophobicContact CB-CD2 4.32Å; W143-L187 HydrophobicContact CG-CD2 4.45Å; N144-L187 HydrophobicContact CB-CB 4.2Å; N144-L187 HydrophobicContact CB-CD2 4.23Å; F148-L187 HydrophobicContact CB-CD1 3.6Å; F148-L187 HydrophobicContact CD1-CD1 3.55Å; F148-L187 HydrophobicContact CD2-CD1 4.09Å; F148-L187 HydrophobicContact CE1-CD1 4.2Å; F148-L187 HydrophobicContact CG-CD1 3.48Å; F148-L187 VanDerWaalsContact CG-CD1 3.48Å; S183-L187 WeakPolarHBondContact O-CB 3.33Å; S183-L187 WeakPolarHBondContact O-CD1 3.46Å; S183-L187 WeakPolarHBondContact O-CG 3.32Å; S183-L187 PolarHBondContact O-N 3.39Å; L187-S189 PolarHBondContact O-N 3.28Å
188C79.1Confident86.3Confident18 Ų1841.4 Ų41.412%0.12222%0.216CC..  trans-74.2115.6175-171.40000110.7N186 N190 K194 I197N186-C188 VanDerWaalsContact C-N 3.29Å; C188-N190 VanDerWaalsContact C-N 3.31Å; C188-K194 WeakPolarHBondContact CB-O 3.28Å; C188-K194 PolarHBondContact SG-O 3.05Å; C188-I197 HydrophobicContact CB-CD1 4.32Å; C188-I197 HydrophobicContact CB-CG1 4.47Å
189S72.3Confident86.2Confident62 Ų6243.8 Ų43.843%0.43422%0.224SC..  trans-86.52.8177.9-46.10000113.4D141 L187 P191D141-S189 PolarHBondContact OD1-OG 2.8Å; L187-S189 PolarHBondContact O-N 3.28Å; S189-P191 VanDerWaalsContact O-CD 3.28Å; S189-P191 WeakPolarHBondContact O-CD 3.45Å
190N74.3Confident86.1Confident42 Ų4248.1 Ų48.123%0.22525%0.247CC..  trans-76.9115.6178.5-174.6-12.2000110.5C188 E192 D193 Q196C188-N190 VanDerWaalsContact C-N 3.31Å; N190-E192 PolarHBondContact OD1-N 3.43Å; N190-D193 PolarHBondContact OD1-N 2.82Å; N190-Q196 PolarHBondContact ND2-OE1 3.13Å
191P71.3Confident86Confident115 Ų11550.1 Ų50.175%0.74726%0.258SS*.SBendtrans-74.1-22.8-179.429.3-33.5000114.2S189S189-P191 VanDerWaalsContact O-CD 3.28Å; S189-P191 WeakPolarHBondContact O-CD 3.45Å
192E77.5Confident86Confident188 Ų18848.8 Ų48.888%0.87925%0.253SS*.SBendtrans-84.7-36.1-179.6-63.1-173.5167.300111.9N190N190-E192 PolarHBondContact OD1-N 3.43Å
193D81.5Confident86.1Confident54 Ų5447.4 Ų47.429%0.28925%0.246SC..  trans-142.491.4-178.3-170.1-20.6000111.2N190 L195 Q196 R199N190-D193 PolarHBondContact OD1-N 2.82Å; D193-L195 PolarHBondContact O-N 2.59Å; D193-L195 PolarHBondContact OD1-N 3.29Å; D193-Q196 HydrophobicContact CB-CB 4.27Å; D193-Q196 PolarHBondContact O-N 2.84Å; D193-Q196 PolarHBondContact OD1-N 3.05Å; D193-R199 IonicContact OD1-CZ 2.93Å; D193-R199 IonicContact OD1-NH1 3.6Å; D193-R199 PolarHBondContact OD1-NH1 3.49Å; D193-R199 IonicContact OD1-NH2 2.69Å; D193-R199 IonicContact OD2-CZ 3.26Å; D193-R199 IonicContact OD2-NH1 3.62Å; D193-R199 PolarHBondContact OD2-NH1 3Å; D193-R199 IonicContact OD2-NH2 3.24Å; D193-R199 PolarHBondContact OD2-NH2 2.63Å
194K80.4Confident86.3Confident104 Ų10453.1 Ų53.145%0.45227%0.271SS..THydrogen-bonded Turntrans-62.6-12.2-179.1-62.9-172.9-176.8-176.80113.2E131 C188E131-K194 IonicContact OE2-NZ 3.35Å; C188-K194 WeakPolarHBondContact CB-O 3.28Å; C188-K194 PolarHBondContact SG-O 3.05Å
195L86.9Confident86.4Confident29 Ų2954 Ų5415%0.15228%0.278CS..THydrogen-bonded Turntrans-105.9-5.5-177.2-67.5176.7000113.6V185 D193 I197 Y198 R199 E250 C255V185-L195 HydrophobicContact CG1-CD2 3.92Å; V185-L195 HydrophobicContact CG2-CD2 4.11Å; D193-L195 PolarHBondContact O-N 2.59Å; D193-L195 PolarHBondContact OD1-N 3.29Å; L195-I197 PolarHBondContact O-N 2.88Å; L195-Y198 HydrophobicContact CD2-CD1 4.32Å; L195-Y198 WeakPolarHBondContact O-CB 3.4Å; L195-Y198 PolarHBondContact O-N 2.9Å; L195-Y198 VanDerWaalsContact O-N 3.09Å; L195-R199 VanDerWaalsContact CB-NH1 3.31Å; L195-R199 WeakPolarHBondContact O-CG 3.37Å; L195-R199 PolarHBondContact O-N 3.37Å; L195-E250 HydrophobicContact CD2-CG 4.13Å; L195-C255 HydrophobicContact CD1-CB 3.9Å
196Q87.3Confident86.7Confident76 Ų7653.6 Ų53.636%0.35528%0.276SS..Hα-helixtrans-52.6-51.2-176.3-175.6-178.31700113.2N190 D193 Y198 R199 D200N190-Q196 PolarHBondContact ND2-OE1 3.13Å; D193-Q196 HydrophobicContact CB-CB 4.27Å; D193-Q196 PolarHBondContact O-N 2.84Å; D193-Q196 PolarHBondContact OD1-N 3.05Å; Q196-Y198 VanDerWaalsContact C-N 3.29Å; Q196-Y198 PolarHBondContact O-N 3.06Å; Q196-R199 PolarHBondContact O-N 3.49Å; Q196-D200 WeakPolarHBondContact CG-OD2 3.5Å; Q196-D200 WeakPolarHBondContact O-CB 3.35Å; Q196-D200 PolarHBondContact O-N 3.27Å
197I88.3Confident87.1Confident55 Ų5554.2 Ų54.228%0.28228%0.279SS..Hα-helixtrans-65-37-178.1-56.7-176.6000110.9Y184 C188 L195 N201Y184-I197 HydrophobicContact CD1-CG2 3.98Å; Y184-I197 HydrophobicContact CE1-CG2 4.33Å; C188-I197 HydrophobicContact CB-CD1 4.32Å; C188-I197 HydrophobicContact CB-CG1 4.47Å; L195-I197 PolarHBondContact O-N 2.88Å; I197-N201 WeakPolarHBondContact O-CB 3.17Å; I197-N201 PolarHBondContact O-N 2.84Å; I197-N201 PolarHBondContact O-ND2 3.28Å
198Y92.5Very high87.5Confident0 Ų058 Ų580%030%0.299CS..Iπ-helixtrans-60.9-47.1174.3162.3-102.4000111.4R181 V185 L195 Q196 F202 E203 E250 S257R181-Y198 HydrophobicContact CG-CD2 4.17Å; R181-Y198 HydrophobicContact CG-CE2 3.62Å; V185-Y198 HydrophobicContact CG2-CD1 4.41Å; V185-Y198 HydrophobicContact CG2-CD2 3.74Å; V185-Y198 HydrophobicContact CG2-CE2 4.36Å; V185-Y198 HydrophobicContact CG2-CG 3.78Å; L195-Y198 HydrophobicContact CD2-CD1 4.32Å; L195-Y198 WeakPolarHBondContact O-CB 3.4Å; L195-Y198 PolarHBondContact O-N 2.9Å; L195-Y198 VanDerWaalsContact O-N 3.09Å; Q196-Y198 VanDerWaalsContact C-N 3.29Å; Q196-Y198 PolarHBondContact O-N 3.06Å; Y198-F202 HydrophobicContact CD2-CB 3.96Å; Y198-F202 HydrophobicContact CD2-CD1 4.11Å; Y198-F202 HydrophobicContact CD2-CG 4.36Å; Y198-F202 HydrophobicContact CE2-CB 4.2Å; Y198-F202 AromaticContact CE2-CD1 3.5Å; Y198-F202 HydrophobicContact CE2-CD1 3.5Å; Y198-F202 HydrophobicContact CE2-CE1 4.28Å; Y198-F202 HydrophobicContact CE2-CG 4.19Å; Y198-F202 PolarHBondContact O-N 3.05Å; Y198-E203 HydrophobicContact CE1-CB 4.08Å; Y198-E203 PolarHBondContact O-N 3.3Å; Y198-E250 HydrophobicContact CD1-CB 4.49Å; Y198-E250 HydrophobicContact CE1-CB 3.81Å; Y198-E250 HydrophobicContact CE2-CB 4.39Å; Y198-E250 PolarHBondContact OH-N 3.28Å; Y198-S257 WeakPolarHBondContact CE1-OG 3.38Å; Y198-S257 PolarHBondContact OH-OG 2.8Å
199R92.3Very high88.2Confident69 Ų6958.5 Ų58.526%0.2630%0.303SS..Iπ-helixtrans-65.2-47.9-179.7-63.7-161.4-56.1-83.1-14.2112.4D193 L195 Q196 N201 E203 K204D193-R199 IonicContact OD1-CZ 2.93Å; D193-R199 IonicContact OD1-NH1 3.6Å; D193-R199 PolarHBondContact OD1-NH1 3.49Å; D193-R199 IonicContact OD1-NH2 2.69Å; D193-R199 IonicContact OD2-CZ 3.26Å; D193-R199 IonicContact OD2-NH1 3.62Å; D193-R199 PolarHBondContact OD2-NH1 3Å; D193-R199 IonicContact OD2-NH2 3.24Å; D193-R199 PolarHBondContact OD2-NH2 2.63Å; L195-R199 VanDerWaalsContact CB-NH1 3.31Å; L195-R199 WeakPolarHBondContact O-CG 3.37Å; L195-R199 PolarHBondContact O-N 3.37Å; Q196-R199 PolarHBondContact O-N 3.49Å; R199-N201 PolarHBondContact O-N 3.02Å; R199-E203 WeakPolarHBondContact CA-OE2 3.42Å; R199-E203 VanDerWaalsContact CB-OE2 3.22Å; R199-E203 WeakPolarHBondContact CB-OE2 3.36Å; R199-E203 WeakPolarHBondContact CG-OE2 3.26Å; R199-K204 WeakPolarHBondContact O-CB 3.45Å; R199-K204 PolarHBondContact O-N 3.48Å; R199-K204 VanDerWaalsContact O-N 3.12Å
200D90.9Very high89.3Confident93 Ų9355.5 Ų55.550%0.49728%0.282SS..Iπ-helixtrans-69-18.1-176.2-69.6-17.9000114.1Q196Q196-D200 WeakPolarHBondContact CG-OD2 3.5Å; Q196-D200 WeakPolarHBondContact O-CB 3.35Å; Q196-D200 PolarHBondContact O-N 3.27Å
201N92.5Very high90.3Very high41 Ų4157.4 Ų57.422%0.21929%0.29CS..Iπ-helixtrans-121.9-74.6-174.5-60.1-93.7000112.1Q156 Y184 I197 R199 A205Q156-N201 PolarHBondContact OE1-O 3.01Å; Y184-N201 HydrophobicContact CD1-CB 4.11Å; Y184-N201 HydrophobicContact CE1-CB 3.45Å; Y184-N201 VanDerWaalsContact CE1-CB 3.45Å; I197-N201 WeakPolarHBondContact O-CB 3.17Å; I197-N201 PolarHBondContact O-N 2.84Å; I197-N201 PolarHBondContact O-ND2 3.28Å; R199-N201 PolarHBondContact O-N 3.02Å; N201-A205 VanDerWaalsContact O-CB 3.22Å; N201-A205 WeakPolarHBondContact O-CB 3.38Å; N201-A205 PolarHBondContact O-N 3.12Å
202F94.8Very high91.5Very high0 Ų061.3 Ų61.30%029%0.289CS..Iπ-helixtrans-69.4-51-171.6-175.1-86.6000112.2A159 M160 V177 V180 R181 Y184 Y198 A205 Y206 L249A159-F202 HydrophobicContact CB-CE2 4.44Å; M160-F202 HydrophobicContact CE-CD2 3.95Å; M160-F202 HydrophobicContact CE-CE1 4.43Å; M160-F202 HydrophobicContact CE-CE2 3.57Å; M160-F202 HydrophobicContact CE-CZ 3.85Å; V177-F202 HydrophobicContact CG1-CZ 3.93Å; V180-F202 HydrophobicContact CB-CE2 4.22Å; V180-F202 HydrophobicContact CG1-CD2 3.84Å; V180-F202 HydrophobicContact CG1-CE2 3.83Å; R181-F202 HydrophobicContact CB-CD1 4.26Å; R181-F202 HydrophobicContact CB-CE1 3.82Å; R181-F202 HydrophobicContact CB-CE2 4.22Å; R181-F202 HydrophobicContact CB-CZ 3.8Å; R181-F202 HydrophobicContact CG-CD1 4.31Å; R181-F202 HydrophobicContact CG-CE1 4.08Å; Y184-F202 HydrophobicContact CD2-CB 3.6Å; Y184-F202 AromaticContact CD2-CD2 3.87Å; Y184-F202 HydrophobicContact CD2-CD2 3.87Å; Y184-F202 HydrophobicContact CD2-CG 4.11Å; Y184-F202 HydrophobicContact CE2-CB 3.99Å; Y184-F202 HydrophobicContact CE2-CD2 4.14Å; Y184-F202 HydrophobicContact CG-CB 3.92Å; Y198-F202 HydrophobicContact CD2-CB 3.96Å; Y198-F202 HydrophobicContact CD2-CD1 4.11Å; Y198-F202 HydrophobicContact CD2-CG 4.36Å; Y198-F202 HydrophobicContact CE2-CB 4.2Å; Y198-F202 AromaticContact CE2-CD1 3.5Å; Y198-F202 HydrophobicContact CE2-CD1 3.5Å; Y198-F202 HydrophobicContact CE2-CE1 4.28Å; Y198-F202 HydrophobicContact CE2-CG 4.19Å; Y198-F202 PolarHBondContact O-N 3.05Å; F202-A205 PolarHBondContact O-N 3.01Å; F202-Y206 HydrophobicContact CE1-CD2 4.14Å; F202-Y206 HydrophobicContact CZ-CD2 4.41Å; F202-Y206 VanDerWaalsContact O-CB 3.27Å; F202-Y206 WeakPolarHBondContact O-CB 3.16Å; F202-Y206 PolarHBondContact O-N 3.16Å; F202-L249 HydrophobicContact CE1-CD2 4.22Å
203E95Very high92.3Very high16 Ų1653.1 Ų53.18%0.07525%0.251CS..Iπ-helixtrans-60.4-50.8178.5-177.2-176.1-13100110Y198 R199 A205 Y206 L207 S257Y198-E203 HydrophobicContact CE1-CB 4.08Å; Y198-E203 PolarHBondContact O-N 3.3Å; R199-E203 WeakPolarHBondContact CA-OE2 3.42Å; R199-E203 VanDerWaalsContact CB-OE2 3.22Å; R199-E203 WeakPolarHBondContact CB-OE2 3.36Å; R199-E203 WeakPolarHBondContact CG-OE2 3.26Å; E203-A205 PolarHBondContact O-N 3.46Å; E203-Y206 CarbonylContact O-C 3.56Å; E203-Y206 WeakPolarHBondContact O-CA 3.38Å; E203-Y206 WeakPolarHBondContact O-CB 3.11Å; E203-Y206 PolarHBondContact O-N 3.35Å; E203-L207 HydrophobicContact CG-CD1 4.08Å; E203-L207 HydrophobicContact CG-CG 4.31Å; E203-L207 WeakPolarHBondContact O-CG 3.35Å; E203-L207 PolarHBondContact O-N 2.91Å; E203-S257 WeakPolarHBondContact OE1-CA 3.13Å; E203-S257 WeakPolarHBondContact OE1-CB 3.48Å; E203-S257 PolarHBondContact OE1-OG 2.86Å
204K95.3Very high93Very high120 Ų12050.6 Ų50.652%0.52224%0.237SC..Hα-helixtrans-53-50.5176.4-176.5175.7-178.5177.30112.7R199 Y206 L207 D208R199-K204 WeakPolarHBondContact O-CB 3.45Å; R199-K204 PolarHBondContact O-N 3.48Å; R199-K204 VanDerWaalsContact O-N 3.12Å; K204-Y206 VanDerWaalsContact C-N 3.28Å; K204-Y206 PolarHBondContact O-N 2.96Å; K204-L207 PolarHBondContact O-N 3.27Å; K204-D208 WeakPolarHBondContact O-CB 3.37Å; K204-D208 PolarHBondContact O-N 3.18Å
205A95.9Very high93.6Very high18 Ų1854.1 Ų54.115%0.14925%0.248CC..Hα-helixtrans-64.6-33.5178.400000112.9Q156 M160 N201 F202 E203 S209Q156-A205 HydrophobicContact CG-CB 4.03Å; M160-A205 HydrophobicContact CG-CB 4.35Å; N201-A205 VanDerWaalsContact O-CB 3.22Å; N201-A205 WeakPolarHBondContact O-CB 3.38Å; N201-A205 PolarHBondContact O-N 3.12Å; F202-A205 PolarHBondContact O-N 3.01Å; E203-A205 PolarHBondContact O-N 3.46Å; A205-S209 WeakPolarHBondContact O-CB 3.5Å; A205-S209 PolarHBondContact O-N 2.97Å
206Y96.7Very high93.9Very high1 Ų157.7 Ų57.70%0.00427%0.271CS..Hα-helixtrans-65.3-48.2174.8-165.4-75.2000111.1M160 V163 F202 E203 K204 S209 T210 R244 Y248 L249 L261M160-Y206 HydrophobicContact CE-CD2 4.12Å; M160-Y206 HydrophobicContact SD-CD2 4.16Å; M160-Y206 HydrophobicContact SD-CG 4.45Å; V163-Y206 HydrophobicContact CG1-CE2 3.93Å; V163-Y206 HydrophobicContact CG2-CE2 3.97Å; F202-Y206 HydrophobicContact CE1-CD2 4.14Å; F202-Y206 HydrophobicContact CZ-CD2 4.41Å; F202-Y206 VanDerWaalsContact O-CB 3.27Å; F202-Y206 WeakPolarHBondContact O-CB 3.16Å; F202-Y206 PolarHBondContact O-N 3.16Å; E203-Y206 CarbonylContact O-C 3.56Å; E203-Y206 WeakPolarHBondContact O-CA 3.38Å; E203-Y206 WeakPolarHBondContact O-CB 3.11Å; E203-Y206 PolarHBondContact O-N 3.35Å; K204-Y206 VanDerWaalsContact C-N 3.28Å; K204-Y206 PolarHBondContact O-N 2.96Å; Y206-S209 PolarHBondContact O-N 3.16Å; Y206-T210 WeakPolarHBondContact O-CB 3.5Å; Y206-T210 PolarHBondContact O-N 3.07Å; Y206-T210 PolarHBondContact O-OG1 2.65Å; Y206-R244 WeakPolarHBondContact OH-CD 3.5Å; Y206-R244 WeakPolarHBondContact OH-CG 3.34Å; Y206-Y248 HydrophobicContact CE2-CD2 4.48Å; Y206-L249 HydrophobicContact CD1-CD1 4.44Å; Y206-L249 HydrophobicContact CD1-CD2 3.91Å; Y206-L249 HydrophobicContact CD2-CD2 3.94Å; Y206-L249 HydrophobicContact CE1-CD1 4.42Å; Y206-L249 HydrophobicContact CE1-CD2 4.24Å; Y206-L249 HydrophobicContact CE1-CG 4.45Å; Y206-L249 HydrophobicContact CE2-CD2 4.25Å; Y206-L249 HydrophobicContact CG-CD2 3.76Å; Y206-L261 HydrophobicContact CD1-CD1 3.81Å; Y206-L261 HydrophobicContact CE1-CD1 3.71Å; Y206-L261 HydrophobicContact CE1-CD2 3.74Å; Y206-L261 HydrophobicContact CE1-CG 4.37Å
207L96.2Very high94.2Very high33 Ų3357 Ų5717%0.17327%0.268CS..Hα-helixtrans-60.9-52.1176.5-64.1178.3000110.9E203 K204 S209 T210 E211 A260 L261 C264E203-L207 HydrophobicContact CG-CD1 4.08Å; E203-L207 HydrophobicContact CG-CG 4.31Å; E203-L207 WeakPolarHBondContact O-CG 3.35Å; E203-L207 PolarHBondContact O-N 2.91Å; K204-L207 PolarHBondContact O-N 3.27Å; L207-S209 VanDerWaalsContact C-N 3.3Å; L207-S209 PolarHBondContact O-N 3.41Å; L207-T210 WeakPolarHBondContact O-CA 3.37Å; L207-T210 WeakPolarHBondContact O-CB 3.3Å; L207-T210 PolarHBondContact O-N 2.99Å; L207-E211 PolarHBondContact O-N 2.85Å; L207-A260 HydrophobicContact CD1-CB 4.4Å; L207-L261 VanDerWaalsContact CD2-CA 3.4Å; L207-L261 HydrophobicContact CD2-CB 3.87Å; L207-L261 HydrophobicContact CD2-CD1 3.69Å; L207-L261 HydrophobicContact CD2-CG 4.41Å; L207-C264 HydrophobicContact CD2-CB 4.21Å
208D95.9Very high94.5Very high84 Ų8454.4 Ų54.445%0.44925%0.254SS..Hα-helixtrans-57.9-41.8-180-70.3-12.9000111.9K204 R212K204-D208 WeakPolarHBondContact O-CB 3.37Å; K204-D208 PolarHBondContact O-N 3.18Å; D208-R212 VanDerWaalsContact O-CB 3.26Å; D208-R212 WeakPolarHBondContact O-CB 3.44Å; D208-R212 PolarHBondContact O-N 3.04Å
209S95Very high94.6Very high28 Ų2857.1 Ų57.120%0.19627%0.272CS..Hα-helixtrans-65-40.9176.4-177.50000112.1A205 Y206 L207 F213A205-S209 WeakPolarHBondContact O-CB 3.5Å; A205-S209 PolarHBondContact O-N 2.97Å; Y206-S209 PolarHBondContact O-N 3.16Å; L207-S209 VanDerWaalsContact C-N 3.3Å; L207-S209 PolarHBondContact O-N 3.41Å; S209-F213 WeakPolarHBondContact O-CB 3.49Å; S209-F213 PolarHBondContact O-N 3.44Å
210T95.5Very high94.7Very high0 Ų056.4 Ų56.40%028%0.277CS..Hα-helixtrans-65.9-48.9177.9-52.40000111.2R167 Y206 L207 R212 F213 Y214 L261 C265R167-T210 PolarHBondContact NH2-OG1 2.99Å; Y206-T210 WeakPolarHBondContact O-CB 3.5Å; Y206-T210 PolarHBondContact O-N 3.07Å; Y206-T210 PolarHBondContact O-OG1 2.65Å; L207-T210 WeakPolarHBondContact O-CA 3.37Å; L207-T210 WeakPolarHBondContact O-CB 3.3Å; L207-T210 PolarHBondContact O-N 2.99Å; T210-R212 PolarHBondContact O-N 2.97Å; T210-F213 WeakPolarHBondContact O-CB 3.39Å; T210-F213 PolarHBondContact O-N 3.17Å; T210-Y214 HydrophobicContact CG2-CD2 3.88Å; T210-Y214 HydrophobicContact CG2-CE2 3.78Å; T210-Y214 WeakPolarHBondContact O-CD2 3.36Å; T210-Y214 PolarHBondContact O-N 3.34Å; T210-Y214 VanDerWaalsContact O-N 3.11Å; T210-L261 HydrophobicContact CG2-CD1 3.78Å; T210-C265 VanDerWaalsContact CG2-SG 3.56Å
211E95.4Very high94.9Very high82 Ų8255.2 Ų55.238%0.38327%0.267SS..Hα-helixtrans-59-49.3178.1-164.8-164.9152.400110.5L207 F213 Y214 R215L207-E211 PolarHBondContact O-N 2.85Å; E211-F213 VanDerWaalsContact C-N 3.3Å; E211-F213 PolarHBondContact O-N 3.02Å; E211-Y214 PolarHBondContact O-N 3.47Å; E211-R215 WeakPolarHBondContact O-CB 3.46Å; E211-R215 PolarHBondContact O-N 2.87Å; E211-R215 IonicContact OE1-NH1 3.78Å
212R95Very high95Very high196 Ų19654.5 Ų54.574%0.7426%0.262SS*.Hα-helixtrans-60.4-39.6179.8-174.4176.7-179.4178.11112.5D208 T210 T216D208-R212 VanDerWaalsContact O-CB 3.26Å; D208-R212 WeakPolarHBondContact O-CB 3.44Å; D208-R212 PolarHBondContact O-N 3.04Å; T210-R212 PolarHBondContact O-N 2.97Å; R212-T216 PolarHBondContact O-N 2.83Å; R212-T216 PolarHBondContact O-OG1 2.66Å
213F95.6Very high95Very high17 Ų1762.6 Ų62.68%0.07530%0.3CS..Hα-helixtrans-60-55.3176.7-179.7-96.4000111.1H164 R167 L168 S209 T210 E211 T216 Q217H164-F213 AromaticContact CE1-CD2 3.59Å; H164-F213 AromaticContact CE1-CE2 3.93Å; H164-F213 AromaticContact ND1-CD2 3.56Å; R167-F213 HydrophobicContact CB-CE1 3.94Å; R167-F213 HydrophobicContact CB-CE2 3.99Å; R167-F213 HydrophobicContact CB-CZ 3.61Å; R167-F213 HydrophobicContact CG-CE1 4.42Å; L168-F213 HydrophobicContact CD2-CE2 4.05Å; L168-F213 HydrophobicContact CD2-CZ 4.25Å; L168-F213 HydrophobicContact CG-CE2 4.38Å; S209-F213 WeakPolarHBondContact O-CB 3.49Å; S209-F213 PolarHBondContact O-N 3.44Å; T210-F213 WeakPolarHBondContact O-CB 3.39Å; T210-F213 PolarHBondContact O-N 3.17Å; E211-F213 VanDerWaalsContact C-N 3.3Å; E211-F213 PolarHBondContact O-N 3.02Å; F213-T216 PolarHBondContact O-N 2.84Å; F213-Q217 PolarHBondContact O-N 3.21Å
214Y95.8Very high95Very high1 Ų168.6 Ų68.60%0.00433%0.328CS..Hα-helixtrans-72.1-32.5-177.5-71.2-58000113.5T210 E211 T216 Q217 A218 K237 E241 L269T210-Y214 HydrophobicContact CG2-CD2 3.88Å; T210-Y214 HydrophobicContact CG2-CE2 3.78Å; T210-Y214 WeakPolarHBondContact O-CD2 3.36Å; T210-Y214 PolarHBondContact O-N 3.34Å; T210-Y214 VanDerWaalsContact O-N 3.11Å; E211-Y214 PolarHBondContact O-N 3.47Å; Y214-T216 PolarHBondContact O-N 3.2Å; Y214-Q217 PolarHBondContact O-N 3.03Å; Y214-A218 WeakPolarHBondContact O-CB 3.38Å; Y214-A218 PolarHBondContact O-N 3.04Å; Y214-K237 HydrophobicContact CE1-CB 4.1Å; Y214-K237 HydrophobicContact CE1-CD 4.19Å; Y214-K237 HydrophobicContact CE1-CG 4.18Å; Y214-E241 HydrophobicContact CE2-CG 3.7Å; Y214-E241 WeakPolarHBondContact OH-CG 3.34Å; Y214-E241 PolarHBondContact OH-OE1 2.95Å; Y214-E241 VanDerWaalsContact OH-OE1 3.1Å; Y214-L269 HydrophobicContact CD1-CD1 4.13Å; Y214-L269 HydrophobicContact CD1-CD2 3.6Å; Y214-L269 HydrophobicContact CD1-CG 4.08Å; Y214-L269 HydrophobicContact CD2-CD1 4.25Å; Y214-L269 HydrophobicContact CD2-CG 4.44Å; Y214-L269 HydrophobicContact CE1-CD1 4.14Å; Y214-L269 HydrophobicContact CE1-CD2 4.17Å; Y214-L269 HydrophobicContact CE2-CD1 4.28Å; Y214-L269 HydrophobicContact CG-CD1 4.17Å; Y214-L269 HydrophobicContact CG-CD2 3.96Å; Y214-L269 HydrophobicContact CG-CG 3.99Å
215R93.4Very high95Very high178 Ų17865.9 Ų65.967%0.67232%0.32SS*.Hα-helixtrans-60.5-26.2173.8-170.6171.1-178.8164.3-0.5112.8E211 P219E211-R215 WeakPolarHBondContact O-CB 3.46Å; E211-R215 PolarHBondContact O-N 2.87Å; E211-R215 IonicContact OE1-NH1 3.78Å; R215-P219 WeakPolarHBondContact O-CD 3.47Å; R215-P219 WeakPolarHBondContact O-CG 3.33Å
216T92.5Very high94.9Very high104 Ų10466.6 Ų66.664%0.63833%0.329SS*.Hα-helixtrans-89.5-46.2175.7-51.70000111.6R212 F213 Y214R212-T216 PolarHBondContact O-N 2.83Å; R212-T216 PolarHBondContact O-OG1 2.66Å; F213-T216 PolarHBondContact O-N 2.84Å; Y214-T216 PolarHBondContact O-N 3.2Å
217Q93.4Very high94.8Very high61 Ų6167.6 Ų67.629%0.28534%0.335SS..Hα-helixtrans-77.6-39.1-172.6-165.9176.93700113.2F213 Y214 S220 Y221 Y233F213-Q217 PolarHBondContact O-N 3.21Å; Y214-Q217 PolarHBondContact O-N 3.03Å; Q217-S220 PolarHBondContact O-N 3.12Å; Q217-Y221 PolarHBondContact O-N 2.94Å; Q217-Y233 VanDerWaalsContact CD-OH 3.24Å; Q217-Y233 PolarHBondContact OE1-OH 3.42Å
218A94.9Very high94.6Very high0 Ų068.9 Ų68.90%034%0.34CS..Hα-helixtrans-63.4-46.7-172.800000113.8Y214 S220 Y221 L222 Y230 L269 F273Y214-A218 WeakPolarHBondContact O-CB 3.38Å; Y214-A218 PolarHBondContact O-N 3.04Å; A218-S220 VanDerWaalsContact C-N 3.33Å; A218-S220 PolarHBondContact O-N 3.28Å; A218-Y221 PolarHBondContact O-N 3.35Å; A218-L222 WeakPolarHBondContact O-CB 3.45Å; A218-L222 PolarHBondContact O-N 3.34Å; A218-Y230 HydrophobicContact CB-CE2 3.94Å; A218-L269 HydrophobicContact CB-CD2 4.08Å; A218-F273 HydrophobicContact CB-CE2 3.6Å; A218-F273 HydrophobicContact CB-CZ 3.76Å
219P94.8Very high94.6Very high58 Ų5868.5 Ų68.538%0.37734%0.338SS..Hα-helixtrans-60.9-41.3176.8-19.229000112.7R215 L222 Q223 F273R215-P219 WeakPolarHBondContact O-CD 3.47Å; R215-P219 WeakPolarHBondContact O-CG 3.33Å; P219-L222 PolarHBondContact O-N 3.44Å; P219-Q223 WeakPolarHBondContact O-CB 3.47Å; P219-Q223 PolarHBondContact O-N 2.72Å; P219-F273 HydrophobicContact CB-CE1 4.37Å; P219-F273 HydrophobicContact CB-CZ 4.32Å; P219-F273 HydrophobicContact CG-CE1 4.29Å; P219-F273 HydrophobicContact CG-CZ 3.81Å
220S94.3Very high94.7Very high53 Ų5367.1 Ų67.137%0.37133%0.329SS..Hα-helixtrans-64.5-41.6178.7-174.30000111.8Q217 A218 Q224Q217-S220 PolarHBondContact O-N 3.12Å; A218-S220 VanDerWaalsContact C-N 3.33Å; A218-S220 PolarHBondContact O-N 3.28Å; S220-Q224 VanDerWaalsContact O-CG 3.31Å; S220-Q224 WeakPolarHBondContact O-CG 3.41Å; S220-Q224 PolarHBondContact O-N 2.98Å; S220-Q224 PolarHBondContact OG-NE2 2.97Å
221Y95.3Very high94.7Very high69 Ų6967.2 Ų67.227%0.27133%0.329SS..Hα-helixtrans-65.7-43.6178.1-168.6-82.9000111.4Q217 A218 Q224 N225 Y230 Y233Q217-Y221 PolarHBondContact O-N 2.94Å; A218-Y221 PolarHBondContact O-N 3.35Å; Y221-Q224 PolarHBondContact O-N 2.83Å; Y221-N225 HydrophobicContact CD1-CB 4.28Å; Y221-N225 HydrophobicContact CE1-CB 3.92Å; Y221-N225 WeakPolarHBondContact O-CB 3.43Å; Y221-N225 PolarHBondContact O-N 2.93Å; Y221-N225 PolarHBondContact O-ND2 2.9Å; Y221-Y230 HydrophobicContact CD1-CD2 4.1Å; Y221-Y233 AromaticContact CD1-CD1 3.95Å; Y221-Y233 HydrophobicContact CD1-CD1 3.95Å; Y221-Y233 HydrophobicContact CD1-CD2 4.17Å; Y221-Y233 AromaticContact CD1-CG 3.72Å; Y221-Y233 HydrophobicContact CD1-CG 3.72Å; Y221-Y233 AromaticContact CD2-CD2 3.83Å; Y221-Y233 HydrophobicContact CD2-CD2 3.83Å; Y221-Y233 AromaticContact CD2-CE2 3.95Å; Y221-Y233 HydrophobicContact CD2-CE2 3.95Å; Y221-Y233 HydrophobicContact CD2-CG 4.23Å; Y221-Y233 HydrophobicContact CE1-CD1 4.32Å; Y221-Y233 HydrophobicContact CE1-CD2 4.03Å; Y221-Y233 AromaticContact CE1-CG 3.65Å; Y221-Y233 HydrophobicContact CE1-CG 3.65Å; Y221-Y233 AromaticContact CE2-CD2 3.67Å; Y221-Y233 HydrophobicContact CE2-CD2 3.67Å; Y221-Y233 HydrophobicContact CE2-CE2 4.17Å; Y221-Y233 HydrophobicContact CE2-CG 4.17Å; Y221-Y233 HydrophobicContact CG-CD1 4.15Å; Y221-Y233 HydrophobicContact CG-CD2 4.07Å; Y221-Y233 HydrophobicContact CG-CE1 4.36Å; Y221-Y233 HydrophobicContact CG-CE2 4.27Å; Y221-Y233 HydrophobicContact CG-CG 4.01Å; Y221-Y233 AromaticContact CZ-CD2 3.77Å; Y221-Y233 AromaticContact CZ-CG 3.88Å
222L95.2Very high94.7Very high25 Ų2569.5 Ų69.513%0.13134%0.338CS..Hα-helixtrans-59.4-46.7177.3177.663000111.6A218 P219 Q224 G226 V227 Y230 F273 T276A218-L222 WeakPolarHBondContact O-CB 3.45Å; A218-L222 PolarHBondContact O-N 3.34Å; P219-L222 PolarHBondContact O-N 3.44Å; L222-Q224 VanDerWaalsContact C-N 3.33Å; L222-Q224 PolarHBondContact O-N 3.21Å; L222-G226 WeakPolarHBondContact O-CA 3.47Å; L222-G226 PolarHBondContact O-N 3.43Å; L222-V227 HydrophobicContact CD1-CB 4.47Å; L222-V227 HydrophobicContact CD1-CG2 4.14Å; L222-Y230 HydrophobicContact CB-CD2 3.7Å; L222-Y230 HydrophobicContact CB-CE2 4.19Å; L222-Y230 HydrophobicContact CB-CG 4.11Å; L222-Y230 HydrophobicContact CD1-CD1 4.15Å; L222-Y230 HydrophobicContact CD1-CD2 4.2Å; L222-Y230 HydrophobicContact CD1-CG 3.7Å; L222-Y230 HydrophobicContact CG-CD2 4.48Å; L222-Y230 HydrophobicContact CG-CG 4.43Å; L222-F273 HydrophobicContact CD2-CD1 3.4Å; L222-F273 HydrophobicContact CD2-CE1 3.78Å; L222-F273 HydrophobicContact CD2-CG 4.31Å; L222-T276 HydrophobicContact CD2-CG2 4.24Å
223Q94.1Very high94.8Very high170 Ų17061 Ų6179%0.79431%0.306SS*.Hα-helixtrans-62.7-38-179.4-172.2-179.52300112.7P219P219-Q223 WeakPolarHBondContact O-CB 3.47Å; P219-Q223 PolarHBondContact O-N 2.72Å
224Q94.8Very high94.8Very high142 Ų14260.2 Ų60.266%0.66430%0.302SS*.Hα-helixtrans-81-34.1-176.4-69.3171.712.500113.3S220 Y221 L222S220-Q224 VanDerWaalsContact O-CG 3.31Å; S220-Q224 WeakPolarHBondContact O-CG 3.41Å; S220-Q224 PolarHBondContact O-N 2.98Å; S220-Q224 PolarHBondContact OG-NE2 2.97Å; Y221-Q224 PolarHBondContact O-N 2.83Å; L222-Q224 VanDerWaalsContact C-N 3.33Å; L222-Q224 PolarHBondContact O-N 3.21Å
225N95.1Very high94.8Very high64 Ų6461.5 Ų61.534%0.34231%0.309SS..Hα-helixtrans-114.2-10.6-168-58.7-79.4000114.3Y221 N229Y221-N225 HydrophobicContact CD1-CB 4.28Å; Y221-N225 HydrophobicContact CE1-CB 3.92Å; Y221-N225 WeakPolarHBondContact O-CB 3.43Å; Y221-N225 PolarHBondContact O-N 2.93Å; Y221-N225 PolarHBondContact O-ND2 2.9Å; N225-N229 HydrophobicContact CB-CB 3.83Å; N225-N229 PolarHBondContact O-ND2 3.01Å
226G94.3Very high94.9Very high33 Ų3354.9 Ų54.934%0.3429%0.293SS..Hα-helixtrans77.3170.4-176.800000114.3L222 Q228 Y230L222-G226 WeakPolarHBondContact O-CA 3.47Å; L222-G226 PolarHBondContact O-N 3.43Å; G226-Q228 PolarHBondContact O-N 3.35Å; G226-Y230 WeakPolarHBondContact O-CB 3.16Å; G226-Y230 PolarHBondContact O-N 3.18Å
227V94.6Very high95.1Very high22 Ų2251.5 Ų51.513%0.13327%0.269CS..Hα-helixtrans-61.8-42.7-169.8-175.70000113.1L222 N229 Y230 M231 T276 I277 E280L222-V227 HydrophobicContact CD1-CB 4.47Å; L222-V227 HydrophobicContact CD1-CG2 4.14Å; V227-N229 PolarHBondContact O-N 3.43Å; V227-Y230 WeakPolarHBondContact O-CB 3.47Å; V227-Y230 PolarHBondContact O-N 3.4Å; V227-M231 PolarHBondContact O-N 3.11Å; V227-T276 HydrophobicContact CG2-CG2 3.9Å; V227-I277 HydrophobicContact CG1-CG1 4.3Å; V227-E280 HydrophobicContact CB-CG 3.93Å; V227-E280 HydrophobicContact CG1-CG 3.87Å; V227-E280 HydrophobicContact CG2-CG 4.1Å
228Q92Very high95.2Very high59 Ų5948.8 Ų48.828%0.27626%0.257SS..Hα-helixtrans-67-41.7-174.4-54.6-170.45.400112.3G226 Y230 M231 K232 M284 K292G226-Q228 PolarHBondContact O-N 3.35Å; Q228-Y230 VanDerWaalsContact C-N 3.34Å; Q228-M231 PolarHBondContact O-N 3.33Å; Q228-K232 PolarHBondContact O-N 3.29Å; Q228-M284 HydrophobicContact CG-CE 3.73Å; Q228-K292 VanDerWaalsContact OE1-CD 3.31Å; Q228-K292 VanDerWaalsContact OE1-CE 3.22Å
229N94.6Very high95.2Very high76 Ų7653.9 Ų53.941%0.40628%0.279SS..Hα-helixtrans-71.2-34.8174.5-69.1-39.5000111N225 V227 M231 K232 Y233N225-N229 HydrophobicContact CB-CB 3.83Å; N225-N229 PolarHBondContact O-ND2 3.01Å; V227-N229 PolarHBondContact O-N 3.43Å; N229-M231 VanDerWaalsContact C-N 3.35Å; N229-M231 PolarHBondContact O-N 2.96Å; N229-K232 PolarHBondContact O-N 3.04Å; N229-Y233 WeakPolarHBondContact O-CB 3.13Å; N229-Y233 PolarHBondContact O-N 2.88Å
230Y97.1Very high95.3Very high0 Ų054.6 Ų54.60%028%0.277CS..Hα-helixtrans-58.9-42.6173.4-179.3-96.7000112.6A218 Y221 L222 G226 V227 Q228 K232 Y233 A234 L269 F273 I277A218-Y230 HydrophobicContact CB-CE2 3.94Å; Y221-Y230 HydrophobicContact CD1-CD2 4.1Å; L222-Y230 HydrophobicContact CB-CD2 3.7Å; L222-Y230 HydrophobicContact CB-CE2 4.19Å; L222-Y230 HydrophobicContact CB-CG 4.11Å; L222-Y230 HydrophobicContact CD1-CD1 4.15Å; L222-Y230 HydrophobicContact CD1-CD2 4.2Å; L222-Y230 HydrophobicContact CD1-CG 3.7Å; L222-Y230 HydrophobicContact CG-CD2 4.48Å; L222-Y230 HydrophobicContact CG-CG 4.43Å; G226-Y230 WeakPolarHBondContact O-CB 3.16Å; G226-Y230 PolarHBondContact O-N 3.18Å; V227-Y230 WeakPolarHBondContact O-CB 3.47Å; V227-Y230 PolarHBondContact O-N 3.4Å; Q228-Y230 VanDerWaalsContact C-N 3.34Å; Y230-K232 VanDerWaalsContact C-N 3.32Å; Y230-K232 PolarHBondContact O-N 3.18Å; Y230-Y233 HydrophobicContact CD2-CD1 4.19Å; Y230-Y233 HydrophobicContact CE2-CD1 4.14Å; Y230-Y233 HydrophobicContact CE2-CE1 4.43Å; Y230-Y233 CarbonylContact O-C 3.49Å; Y230-Y233 WeakPolarHBondContact O-CB 3.33Å; Y230-Y233 PolarHBondContact O-N 2.83Å; Y230-A234 HydrophobicContact CE1-CB 4.34Å; Y230-A234 WeakPolarHBondContact O-CB 3.44Å; Y230-A234 PolarHBondContact O-N 3.32Å; Y230-L269 WeakPolarHBondContact CE1-O 3.14Å; Y230-L269 PolarHBondContact OH-O 3.36Å; Y230-F273 HydrophobicContact CE1-CB 4.01Å; Y230-F273 HydrophobicContact CE1-CD2 4.05Å; Y230-F273 HydrophobicContact CE1-CG 4.05Å; Y230-F273 AromaticContact CZ-CD2 3.64Å; Y230-F273 AromaticContact CZ-CE2 3.97Å; Y230-F273 AromaticContact CZ-CG 3.98Å; Y230-F273 WeakPolarHBondContact OH-CD2 3.33Å; Y230-F273 WeakPolarHBondContact OH-CE2 3.37Å; Y230-I277 HydrophobicContact CD1-CD1 4.37Å; Y230-I277 HydrophobicContact CD1-CG1 4.49Å; Y230-I277 HydrophobicContact CE1-CD1 4.18Å
231M96.2Very high95.3Very high1 Ų152.1 Ų52.11%0.00526%0.259CS..Hα-helixtrans-59.4-42.8175.8-69.9-167.3-66.400112.2V227 Q228 N229 Y233 A234 D235 I277 M284 L295 M296 L299V227-M231 PolarHBondContact O-N 3.11Å; Q228-M231 PolarHBondContact O-N 3.33Å; N229-M231 VanDerWaalsContact C-N 3.35Å; N229-M231 PolarHBondContact O-N 2.96Å; M231-Y233 VanDerWaalsContact C-N 3.33Å; M231-Y233 PolarHBondContact O-N 3.47Å; M231-A234 PolarHBondContact O-N 3.34Å; M231-D235 PolarHBondContact O-N 2.9Å; M231-I277 HydrophobicContact CG-CG1 4.4Å; M231-I277 HydrophobicContact CG-CG2 4.1Å; M231-I277 HydrophobicContact SD-CG2 3.68Å; M231-M284 HydrophobicContact CE-CE 3.51Å; M231-M284 HydrophobicContact CE-SD 4.17Å; M231-L295 HydrophobicContact CB-CD2 3.77Å; M231-L295 HydrophobicContact CB-CG 4.08Å; M231-M296 HydrophobicContact CE-CB 4.47Å; M231-M296 HydrophobicContact CE-CE 4.2Å; M231-M296 HydrophobicContact SD-CB 3.73Å; M231-M296 HydrophobicContact SD-CE 3.93Å; M231-M296 HydrophobicContact SD-CG 4.09Å; M231-L299 HydrophobicContact CB-CD1 3.7Å; M231-L299 HydrophobicContact CG-CD1 3.88Å; M231-L299 HydrophobicContact SD-CD1 4.49Å
232K96.4Very high95.4Very high130 Ų13053.2 Ų53.257%0.56527%0.267SS*.Hα-helixtrans-63.7-41.8176.3-68.7-179.5178-1790111.3Q228 N229 Y230 A236 L295Q228-K232 PolarHBondContact O-N 3.29Å; N229-K232 PolarHBondContact O-N 3.04Å; Y230-K232 VanDerWaalsContact C-N 3.32Å; Y230-K232 PolarHBondContact O-N 3.18Å; K232-A236 WeakPolarHBondContact O-CB 3.31Å; K232-A236 PolarHBondContact O-N 2.84Å; K232-L295 HydrophobicContact CB-CD2 4.3Å; K232-L295 HydrophobicContact CG-CD2 3.5Å; K232-L295 VanDerWaalsContact CG-CD2 3.5Å
233Y95.8Very high95.4Very high18 Ų1859.5 Ų59.57%0.07129%0.293CS..Hα-helixtrans-61.8-46.9175.2168.2-93.3000111.7Q217 Y221 N229 Y230 M231 A236 K237 L269Q217-Y233 VanDerWaalsContact CD-OH 3.24Å; Q217-Y233 PolarHBondContact OE1-OH 3.42Å; Y221-Y233 AromaticContact CD1-CD1 3.95Å; Y221-Y233 HydrophobicContact CD1-CD1 3.95Å; Y221-Y233 HydrophobicContact CD1-CD2 4.17Å; Y221-Y233 AromaticContact CD1-CG 3.72Å; Y221-Y233 HydrophobicContact CD1-CG 3.72Å; Y221-Y233 AromaticContact CD2-CD2 3.83Å; Y221-Y233 HydrophobicContact CD2-CD2 3.83Å; Y221-Y233 AromaticContact CD2-CE2 3.95Å; Y221-Y233 HydrophobicContact CD2-CE2 3.95Å; Y221-Y233 HydrophobicContact CD2-CG 4.23Å; Y221-Y233 HydrophobicContact CE1-CD1 4.32Å; Y221-Y233 HydrophobicContact CE1-CD2 4.03Å; Y221-Y233 AromaticContact CE1-CG 3.65Å; Y221-Y233 HydrophobicContact CE1-CG 3.65Å; Y221-Y233 AromaticContact CE2-CD2 3.67Å; Y221-Y233 HydrophobicContact CE2-CD2 3.67Å; Y221-Y233 HydrophobicContact CE2-CE2 4.17Å; Y221-Y233 HydrophobicContact CE2-CG 4.17Å; Y221-Y233 HydrophobicContact CG-CD1 4.15Å; Y221-Y233 HydrophobicContact CG-CD2 4.07Å; Y221-Y233 HydrophobicContact CG-CE1 4.36Å; Y221-Y233 HydrophobicContact CG-CE2 4.27Å; Y221-Y233 HydrophobicContact CG-CG 4.01Å; Y221-Y233 AromaticContact CZ-CD2 3.77Å; Y221-Y233 AromaticContact CZ-CG 3.88Å; N229-Y233 WeakPolarHBondContact O-CB 3.13Å; N229-Y233 PolarHBondContact O-N 2.88Å; Y230-Y233 HydrophobicContact CD2-CD1 4.19Å; Y230-Y233 HydrophobicContact CE2-CD1 4.14Å; Y230-Y233 HydrophobicContact CE2-CE1 4.43Å; Y230-Y233 CarbonylContact O-C 3.49Å; Y230-Y233 WeakPolarHBondContact O-CB 3.33Å; Y230-Y233 PolarHBondContact O-N 2.83Å; M231-Y233 VanDerWaalsContact C-N 3.33Å; M231-Y233 PolarHBondContact O-N 3.47Å; Y233-A236 PolarHBondContact O-N 2.79Å; Y233-K237 HydrophobicContact CD1-CG 4.41Å; Y233-K237 HydrophobicContact CD2-CG 4.03Å; Y233-K237 HydrophobicContact CE1-CG 4.07Å; Y233-K237 HydrophobicContact CE2-CD 4.1Å; Y233-K237 HydrophobicContact CE2-CG 3.68Å; Y233-K237 HydrophobicContact CG-CG 4.38Å; Y233-K237 WeakPolarHBondContact O-CB 3.27Å; Y233-K237 VanDerWaalsContact O-CG 3.25Å; Y233-K237 WeakPolarHBondContact O-CG 3.4Å; Y233-K237 PolarHBondContact O-N 3.04Å; Y233-L269 HydrophobicContact CE1-CD2 4.04Å
234A96.6Very high95.4Very high0 Ų052.7 Ų52.70%026%0.26CS..Hα-helixtrans-61.3-47.7178.900000111.6Y230 M231 A236 K237 L238 L269 L299Y230-A234 HydrophobicContact CE1-CB 4.34Å; Y230-A234 WeakPolarHBondContact O-CB 3.44Å; Y230-A234 PolarHBondContact O-N 3.32Å; M231-A234 PolarHBondContact O-N 3.34Å; A234-A236 PolarHBondContact O-N 2.78Å; A234-K237 PolarHBondContact O-N 2.88Å; A234-L238 WeakPolarHBondContact O-CB 3.31Å; A234-L238 VanDerWaalsContact O-CG 3.27Å; A234-L238 WeakPolarHBondContact O-CG 3.27Å; A234-L238 PolarHBondContact O-N 2.9Å; A234-L269 HydrophobicContact CB-CB 4.42Å; A234-L299 HydrophobicContact CB-CD1 4.39Å; A234-L299 HydrophobicContact CB-CD2 4.3Å
235D95.8Very high95.5Very high29 Ų2945.9 Ų45.916%0.15523%0.229CC..Hα-helixtrans-61.1-44.2176.9176.470.3000112.2M231 K239 L295 L299M231-D235 PolarHBondContact O-N 2.9Å; D235-K239 WeakPolarHBondContact O-CG 3.38Å; D235-K239 PolarHBondContact O-N 3.04Å; D235-K239 VanDerWaalsContact O-N 3.16Å; D235-K239 WeakPolarHBondContact OD1-CE 3.48Å; D235-K239 IonicContact OD1-NZ 2.67Å; D235-K239 PolarHBondContact OD1-NZ 3.1Å; D235-K239 WeakPolarHBondContact OD2-CE 3.38Å; D235-K239 IonicContact OD2-NZ 2.84Å; D235-K239 PolarHBondContact OD2-NZ 3.17Å; D235-L295 HydrophobicContact CB-CD1 3.65Å; D235-L299 HydrophobicContact CB-CD2 4.11Å
236A96Very high95.5Very high39 Ų3947.8 Ų47.832%0.32224%0.238SC..Hα-helixtrans-62.3-45.2176.200000111.8K232 Y233 A234 K239 E240K232-A236 WeakPolarHBondContact O-CB 3.31Å; K232-A236 PolarHBondContact O-N 2.84Å; Y233-A236 PolarHBondContact O-N 2.79Å; A234-A236 PolarHBondContact O-N 2.78Å; A236-K239 PolarHBondContact O-N 3.3Å; A236-E240 WeakPolarHBondContact O-CG 3.45Å; A236-E240 PolarHBondContact O-N 3.36Å
237K95.2Very high95.5Very high32 Ų3251.3 Ų51.314%0.13924%0.241CC..Hα-helixtrans-68.4-36.1-179.1-69.3-67160.6-160.80112.8Y214 Y233 A234 E240 E241 L269Y214-K237 HydrophobicContact CE1-CB 4.1Å; Y214-K237 HydrophobicContact CE1-CD 4.19Å; Y214-K237 HydrophobicContact CE1-CG 4.18Å; Y233-K237 HydrophobicContact CD1-CG 4.41Å; Y233-K237 HydrophobicContact CD2-CG 4.03Å; Y233-K237 HydrophobicContact CE1-CG 4.07Å; Y233-K237 HydrophobicContact CE2-CD 4.1Å; Y233-K237 HydrophobicContact CE2-CG 3.68Å; Y233-K237 HydrophobicContact CG-CG 4.38Å; Y233-K237 WeakPolarHBondContact O-CB 3.27Å; Y233-K237 VanDerWaalsContact O-CG 3.25Å; Y233-K237 WeakPolarHBondContact O-CG 3.4Å; Y233-K237 PolarHBondContact O-N 3.04Å; A234-K237 PolarHBondContact O-N 2.88Å; K237-E240 WeakPolarHBondContact CD-OE2 3.46Å; K237-E240 IonicContact NZ-OE1 3.21Å; K237-E240 PolarHBondContact NZ-OE1 3.19Å; K237-E240 IonicContact NZ-OE2 3.93Å; K237-E240 PolarHBondContact NZ-OE2 2.87Å; K237-E240 PolarHBondContact O-N 2.75Å; K237-E241 WeakPolarHBondContact O-CG 3.45Å; K237-E241 PolarHBondContact O-N 3.2Å; K237-L269 HydrophobicContact CB-CD1 3.97Å
238L96Very high95.5Very high5 Ų550.3 Ų50.33%0.02624%0.235CC..Hα-helixtrans-59.6-46.2171.4-73170.3000111.4A234 E240 E241 E242 M262 C265 V266 L269 V270 L299 K302A234-L238 WeakPolarHBondContact O-CB 3.31Å; A234-L238 VanDerWaalsContact O-CG 3.27Å; A234-L238 WeakPolarHBondContact O-CG 3.27Å; A234-L238 PolarHBondContact O-N 2.9Å; L238-E240 VanDerWaalsContact C-N 3.34Å; L238-E240 PolarHBondContact O-N 3.3Å; L238-E241 PolarHBondContact O-N 3.37Å; L238-E242 WeakPolarHBondContact O-CB 3.45Å; L238-E242 PolarHBondContact O-N 3.49Å; L238-M262 HydrophobicContact CB-CE 4.21Å; L238-M262 HydrophobicContact CD2-CE 4.04Å; L238-C265 HydrophobicContact CD2-CB 3.69Å; L238-V266 HydrophobicContact CD1-CG2 4.47Å; L238-V266 HydrophobicContact CD2-CG2 3.89Å; L238-L269 HydrophobicContact CD2-CD1 4.24Å; L238-L269 HydrophobicContact CG-CD1 4.31Å; L238-V270 HydrophobicContact CD1-CG2 4.03Å; L238-L299 HydrophobicContact CD1-CD2 3.91Å; L238-K302 HydrophobicContact CD1-CD 4.16Å
239K95.6Very high95.6Very high107 Ų10747.5 Ų47.547%0.46522%0.222SC..Hα-helixtrans-64.7-36.6176.9-71.1167.8180164.20112.9D235 A236 K243D235-K239 WeakPolarHBondContact O-CG 3.38Å; D235-K239 PolarHBondContact O-N 3.04Å; D235-K239 VanDerWaalsContact O-N 3.16Å; D235-K239 WeakPolarHBondContact OD1-CE 3.48Å; D235-K239 IonicContact OD1-NZ 2.67Å; D235-K239 PolarHBondContact OD1-NZ 3.1Å; D235-K239 WeakPolarHBondContact OD2-CE 3.38Å; D235-K239 IonicContact OD2-NZ 2.84Å; D235-K239 PolarHBondContact OD2-NZ 3.17Å; A236-K239 PolarHBondContact O-N 3.3Å; K239-K243 WeakPolarHBondContact O-CG 3.29Å; K239-K243 PolarHBondContact O-N 3.25Å
240E95.4Very high95.5Very high73 Ų7344 Ų4434%0.34120%0.203SC..Hα-helixtrans-66-47.2174.9-74.3174.9-153.900111.7A236 K237 L238 K243 R244A236-E240 WeakPolarHBondContact O-CG 3.45Å; A236-E240 PolarHBondContact O-N 3.36Å; K237-E240 WeakPolarHBondContact CD-OE2 3.46Å; K237-E240 IonicContact NZ-OE1 3.21Å; K237-E240 PolarHBondContact NZ-OE1 3.19Å; K237-E240 IonicContact NZ-OE2 3.93Å; K237-E240 PolarHBondContact NZ-OE2 2.87Å; K237-E240 PolarHBondContact O-N 2.75Å; L238-E240 VanDerWaalsContact C-N 3.34Å; L238-E240 PolarHBondContact O-N 3.3Å; E240-K243 PolarHBondContact O-N 3.39Å; E240-R244 WeakPolarHBondContact O-CB 3.43Å; E240-R244 PolarHBondContact O-N 3.35Å
241E95.9Very high95.3Very high0 Ų047.9 Ų47.90%023%0.227CC..Hα-helixtrans-66.3-37.2178.8-73-64.913400112.2R167 Y214 K237 L238 K243 R244 A245R167-E241 IonicContact CZ-OE1 3.06Å; R167-E241 IonicContact CZ-OE2 2.98Å; R167-E241 IonicContact NE-OE1 2.79Å; R167-E241 PolarHBondContact NE-OE1 2.87Å; R167-E241 IonicContact NE-OE2 2.81Å; R167-E241 IonicContact NH2-OE1 3.59Å; R167-E241 IonicContact NH2-OE2 3.44Å; R167-E241 PolarHBondContact NH2-OE2 2.88Å; Y214-E241 HydrophobicContact CE2-CG 3.7Å; Y214-E241 WeakPolarHBondContact OH-CG 3.34Å; Y214-E241 PolarHBondContact OH-OE1 2.95Å; Y214-E241 VanDerWaalsContact OH-OE1 3.1Å; K237-E241 WeakPolarHBondContact O-CG 3.45Å; K237-E241 PolarHBondContact O-N 3.2Å; L238-E241 PolarHBondContact O-N 3.37Å; E241-K243 PolarHBondContact O-N 2.84Å; E241-R244 CarbonylContact O-C 3.52Å; E241-R244 WeakPolarHBondContact O-CB 3.23Å; E241-R244 PolarHBondContact O-N 3.15Å; E241-R244 VanDerWaalsContact O-N 3.15Å; E241-R244 IonicContact OE1-CZ 2.95Å; E241-R244 IonicContact OE1-NH1 3.65Å; E241-R244 PolarHBondContact OE1-NH1 2.77Å; E241-A245 WeakPolarHBondContact O-CB 3.47Å; E241-A245 PolarHBondContact O-N 2.8Å
242E95.9Very high94.8Very high93 Ų9353 Ų5344%0.43525%0.246SC..Hα-helixtrans-58.7-48.6174.7-174.3176.7-154.500111.5L238 R244 A245 L246 M262L238-E242 WeakPolarHBondContact O-CB 3.45Å; L238-E242 PolarHBondContact O-N 3.49Å; E242-R244 VanDerWaalsContact C-N 3.27Å; E242-R244 PolarHBondContact O-N 2.73Å; E242-A245 WeakPolarHBondContact O-CB 3.37Å; E242-A245 PolarHBondContact O-N 2.89Å; E242-L246 WeakPolarHBondContact O-CG 3.32Å; E242-L246 PolarHBondContact O-N 3.32Å; E242-M262 HydrophobicContact CB-CE 4.05Å; E242-M262 HydrophobicContact CB-SD 3.68Å; E242-M262 HydrophobicContact CG-SD 4.26Å
243K95.6Very high93.8Very high157 Ų15758.1 Ų58.168%0.68326%0.262SS*.Hα-helixtrans-61.2-38.2175.6-71.7177.2-177.2-179.60112K239 E240 E241 R247K239-K243 WeakPolarHBondContact O-CG 3.29Å; K239-K243 PolarHBondContact O-N 3.25Å; E240-K243 PolarHBondContact O-N 3.39Å; E241-K243 PolarHBondContact O-N 2.84Å; K243-R247 PolarHBondContact O-N 3.11Å
244R95.4Very high92.9Very high26 Ų2666.9 Ų66.910%0.09830%0.303CS..Hα-helixtrans-69.5-40.8178.8-170-178.7-77.698.18.3111.7E166 Y206 E240 E241 E242 R247 Y248E166-R244 WeakPolarHBondContact OE2-CD 3.46Å; E166-R244 IonicContact OE2-CZ 2.8Å; E166-R244 IonicContact OE2-NE 3.81Å; E166-R244 PolarHBondContact OE2-NE 3Å; E166-R244 IonicContact OE2-NH2 3.08Å; Y206-R244 WeakPolarHBondContact OH-CD 3.5Å; Y206-R244 WeakPolarHBondContact OH-CG 3.34Å; E240-R244 WeakPolarHBondContact O-CB 3.43Å; E240-R244 PolarHBondContact O-N 3.35Å; E241-R244 CarbonylContact O-C 3.52Å; E241-R244 WeakPolarHBondContact O-CB 3.23Å; E241-R244 PolarHBondContact O-N 3.15Å; E241-R244 VanDerWaalsContact O-N 3.15Å; E241-R244 IonicContact OE1-CZ 2.95Å; E241-R244 IonicContact OE1-NH1 3.65Å; E241-R244 PolarHBondContact OE1-NH1 2.77Å; E242-R244 VanDerWaalsContact C-N 3.27Å; E242-R244 PolarHBondContact O-N 2.73Å; R244-R247 WeakPolarHBondContact O-CB 3.4Å; R244-R247 PolarHBondContact O-N 3.46Å; R244-R247 VanDerWaalsContact O-N 3.17Å; R244-Y248 HydrophobicContact CG-CD2 3.56Å; R244-Y248 HydrophobicContact CG-CE2 3.61Å; R244-Y248 PolarHBondContact O-N 3.32Å
245A95.2Very high92.4Very high0 Ų067.7 Ų67.70%031%0.309CS..Hα-helixtrans-58.8-50.3174.600000110.8E241 E242 R247 Y248 L249 V258 L261E241-A245 WeakPolarHBondContact O-CB 3.47Å; E241-A245 PolarHBondContact O-N 2.8Å; E242-A245 WeakPolarHBondContact O-CB 3.37Å; E242-A245 PolarHBondContact O-N 2.89Å; A245-R247 PolarHBondContact O-N 2.82Å; A245-R247 VanDerWaalsContact O-N 3.1Å; A245-Y248 PolarHBondContact O-N 2.66Å; A245-L249 HydrophobicContact CB-CD1 3.93Å; A245-L249 HydrophobicContact CB-CG 4.41Å; A245-L249 WeakPolarHBondContact O-CB 3.42Å; A245-L249 PolarHBondContact O-N 2.82Å; A245-V258 HydrophobicContact CB-CB 4.37Å; A245-V258 HydrophobicContact CB-CG1 4.02Å; A245-V258 HydrophobicContact CB-CG2 4.11Å; A245-L261 HydrophobicContact CB-CD2 3.4Å
246L95Very high92.2Very high103 Ų10370.8 Ų70.854%0.53933%0.326SS..Hα-helixtrans-58.1-26.3178.4-72.1170.1000113E242 T251 V258E242-L246 WeakPolarHBondContact O-CG 3.32Å; E242-L246 PolarHBondContact O-N 3.32Å; L246-T251 HydrophobicContact CD2-CG2 4.33Å; L246-V258 HydrophobicContact CD2-CG2 4.29Å
247R94.4Very high92.1Very high108 Ų10869 Ų6941%0.40831%0.31SS..Hα-helixtrans-83.4-41.3178.1-169.9-179.1-175.9-174.76.1113E166 S174 K243 R244 A245E166-R247 IonicContact OE1-NH1 3.99Å; E166-R247 PolarHBondContact OE1-NH1 2.93Å; S174-R247 VanDerWaalsContact CB-NE 3.32Å; S174-R247 PolarHBondContact OG-NH2 2.82Å; K243-R247 PolarHBondContact O-N 3.11Å; R244-R247 WeakPolarHBondContact O-CB 3.4Å; R244-R247 PolarHBondContact O-N 3.46Å; R244-R247 VanDerWaalsContact O-N 3.17Å; A245-R247 PolarHBondContact O-N 2.82Å; A245-R247 VanDerWaalsContact O-N 3.1Å
248Y95.2Very high92.1Very high0 Ų068.3 Ų68.30%031%0.309CS..Hα-helixtrans-109.7-31.3-166.7-61.4-41.1000115.1V163 E166 F172 V177 I178 R181 Y206 R244 A245V163-Y248 HydrophobicContact CG2-CD2 4.5Å; E166-Y248 PolarHBondContact OE1-OH 3.1Å; E166-Y248 WeakPolarHBondContact OE2-CE2 3.14Å; F172-Y248 HydrophobicContact CZ-CE1 4.35Å; F172-Y248 HydrophobicContact CZ-CE2 4.19Å; F172-Y248 AromaticContact CZ-CZ 3.71Å; F172-Y248 WeakPolarHBondContact CZ-OH 3.4Å; V177-Y248 HydrophobicContact CB-CD1 3.98Å; V177-Y248 HydrophobicContact CB-CE1 4.21Å; V177-Y248 HydrophobicContact CB-CG 4.44Å; V177-Y248 HydrophobicContact CG1-CD1 3.78Å; V177-Y248 HydrophobicContact CG1-CD2 4.4Å; V177-Y248 HydrophobicContact CG1-CE1 4.43Å; V177-Y248 HydrophobicContact CG1-CG 3.78Å; I178-Y248 HydrophobicContact CG1-CD1 4.08Å; R181-Y248 WeakPolarHBondContact CG-O 3.39Å; R181-Y248 PolarHBondContact NE-O 2.87Å; Y206-Y248 HydrophobicContact CE2-CD2 4.48Å; R244-Y248 HydrophobicContact CG-CD2 3.56Å; R244-Y248 HydrophobicContact CG-CE2 3.61Å; R244-Y248 PolarHBondContact O-N 3.32Å; A245-Y248 PolarHBondContact O-N 2.66Å
249L94.8Very high92Very high0 Ų073.7 Ų73.70%033%0.334CS..SBendtrans-82.4167178.5-59.5-177.2000111.3F202 Y206 A245 S257 L261F202-L249 HydrophobicContact CE1-CD2 4.22Å; Y206-L249 HydrophobicContact CD1-CD1 4.44Å; Y206-L249 HydrophobicContact CD1-CD2 3.91Å; Y206-L249 HydrophobicContact CD2-CD2 3.94Å; Y206-L249 HydrophobicContact CE1-CD1 4.42Å; Y206-L249 HydrophobicContact CE1-CD2 4.24Å; Y206-L249 HydrophobicContact CE1-CG 4.45Å; Y206-L249 HydrophobicContact CE2-CD2 4.25Å; Y206-L249 HydrophobicContact CG-CD2 3.76Å; A245-L249 HydrophobicContact CB-CD1 3.93Å; A245-L249 HydrophobicContact CB-CG 4.41Å; A245-L249 WeakPolarHBondContact O-CB 3.42Å; A245-L249 PolarHBondContact O-N 2.82Å; L249-S257 WeakPolarHBondContact CD1-O 3.49Å; L249-L261 HydrophobicContact CD1-CB 3.86Å; L249-L261 HydrophobicContact CD1-CD2 4.05Å; L249-L261 HydrophobicContact CD1-CG 4.46Å
250E92.9Very high92Very high4 Ų469.8 Ų69.82%0.01932%0.321CS..  trans-78.1130.6177.9-173.551.4-105.400110.5R181 V185 L195 Y198 R252 C255R181-E250 IonicContact CZ-OE2 3.76Å; R181-E250 IonicContact NH1-OE1 2.8Å; R181-E250 IonicContact NH1-OE2 3.36Å; R181-E250 PolarHBondContact NH1-OE2 3.42Å; V185-E250 HydrophobicContact CG2-CB 4.28Å; V185-E250 HydrophobicContact CG2-CG 4.16Å; L195-E250 HydrophobicContact CD2-CG 4.13Å; Y198-E250 HydrophobicContact CD1-CB 4.49Å; Y198-E250 HydrophobicContact CE1-CB 3.81Å; Y198-E250 HydrophobicContact CE2-CB 4.39Å; Y198-E250 PolarHBondContact OH-N 3.28Å; E250-R252 HydrophobicContact CG-CB 4.43Å; E250-R252 WeakPolarHBondContact OE1-CB 3.41Å; E250-R252 WeakPolarHBondContact OE1-CG 3.32Å; E250-R252 PolarHBondContact OE1-N 3.29Å; E250-R252 IonicContact OE1-NE 3.72Å; E250-R252 PolarHBondContact OE1-NE 3.03Å; E250-R252 IonicContact OE2-NE 2.62Å; E250-C255 HydrophobicContact CG-CB 4.25Å; E250-C255 PolarHBondContact O-SG 3.29Å
251T91.8Very high92Very high80 Ų8066.3 Ų66.349%0.49131%0.305SS..  trans-125.25.4-17356.40000112.8L246 V258L246-T251 HydrophobicContact CD2-CG2 4.33Å; T251-V258 HydrophobicContact CG2-CG2 3.96Å
252R85.7Confident92Very high108 Ų10867.8 Ų67.841%0.40831%0.312SS..SBendtrans-54153.4168.5-77.8171.6-144.1-158.48.1110.7N186 E250 E254 C255N186-R252 PolarHBondContact OD1-NH2 2.57Å; E250-R252 HydrophobicContact CG-CB 4.43Å; E250-R252 WeakPolarHBondContact OE1-CB 3.41Å; E250-R252 WeakPolarHBondContact OE1-CG 3.32Å; E250-R252 PolarHBondContact OE1-N 3.29Å; E250-R252 IonicContact OE1-NE 3.72Å; E250-R252 PolarHBondContact OE1-NE 3.03Å; E250-R252 IonicContact OE2-NE 2.62Å; R252-E254 PolarHBondContact O-N 3.02Å; R252-C255 WeakPolarHBondContact O-CB 3.29Å; R252-C255 PolarHBondContact O-N 3.02Å; R252-C255 VanDerWaalsContact O-N 3.16Å
253R75.9Confident92Very high239 Ų23969.6 Ų69.690%0.90232%0.321SS*.THydrogen-bonded Turntrans-51.7141.5174-69.8-174.4-178.1-162.6-0.1109.6C255R253-C255 VanDerWaalsContact C-N 3.3Å; R253-C255 PolarHBondContact O-N 3.19Å
254E76.5Confident92Very high201 Ų20163 Ų6394%0.93930%0.295SS*.THydrogen-bonded Turntrans77.22.5-178.6-50.5167.8-174.500115.5R252R252-E254 PolarHBondContact O-N 3.02Å
255C85.9Confident92Very high18 Ų1861.8 Ų61.812%0.12229%0.29CS..  trans-101.5128.5171.7-162.60000110.8L195 E250 R252 R253 S257L195-C255 HydrophobicContact CD1-CB 3.9Å; E250-C255 HydrophobicContact CG-CB 4.25Å; E250-C255 PolarHBondContact O-SG 3.29Å; R252-C255 WeakPolarHBondContact O-CB 3.29Å; R252-C255 PolarHBondContact O-N 3.02Å; R252-C255 VanDerWaalsContact O-N 3.16Å; R253-C255 VanDerWaalsContact C-N 3.3Å; R253-C255 PolarHBondContact O-N 3.19Å; C255-S257 PolarHBondContact SG-OG 3.04Å
256N92Very high92Very high94 Ų9462.4 Ų62.450%0.50329%0.294SS..  trans-111.326-178.366.6-29.8000113.2V258 E259 A260N256-V258 VanDerWaalsContact C-N 3.31Å; N256-V258 PolarHBondContact O-N 3.23Å; N256-E259 WeakPolarHBondContact CA-OE2 3.24Å; N256-E259 HydrophobicContact CB-CB 4.5Å; N256-E259 PolarHBondContact O-N 3.43Å; N256-A260 WeakPolarHBondContact O-CB 3.22Å; N256-A260 PolarHBondContact O-N 3.36Å
257S93.6Very high92.1Very high0 Ų060.7 Ų60.70%029%0.285CS..Hα-helixtrans-66.3-32.8-174.2-60.20000113.8Y198 E203 L249 C255 L261Y198-S257 WeakPolarHBondContact CE1-OG 3.38Å; Y198-S257 PolarHBondContact OH-OG 2.8Å; E203-S257 WeakPolarHBondContact OE1-CA 3.13Å; E203-S257 WeakPolarHBondContact OE1-CB 3.48Å; E203-S257 PolarHBondContact OE1-OG 2.86Å; L249-S257 WeakPolarHBondContact CD1-O 3.49Å; C255-S257 PolarHBondContact SG-OG 3.04Å; S257-L261 WeakPolarHBondContact O-CB 3.11Å; S257-L261 PolarHBondContact O-N 3.18Å
258V95.1Very high92.1Very high19 Ų1955.9 Ų55.912%0.11527%0.269CS..Hα-helixtrans-66.6-45.9175.7177.70000109.2A245 L246 T251 N256 L261 M262A245-V258 HydrophobicContact CB-CB 4.37Å; A245-V258 HydrophobicContact CB-CG1 4.02Å; A245-V258 HydrophobicContact CB-CG2 4.11Å; L246-V258 HydrophobicContact CD2-CG2 4.29Å; T251-V258 HydrophobicContact CG2-CG2 3.96Å; N256-V258 VanDerWaalsContact C-N 3.31Å; N256-V258 PolarHBondContact O-N 3.23Å; V258-L261 PolarHBondContact O-N 2.99Å; V258-M262 HydrophobicContact CG1-CG 4.46Å; V258-M262 VanDerWaalsContact O-CG 3.27Å; V258-M262 WeakPolarHBondContact O-CG 3.47Å; V258-M262 PolarHBondContact O-N 3.24Å
259E94.1Very high92.1Very high118 Ų11855.9 Ų55.955%0.55127%0.269SS*.Hα-helixtrans-61.5-44.3176.7-64.282.3173.500111.5N256 L261 M262 E263N256-E259 WeakPolarHBondContact CA-OE2 3.24Å; N256-E259 HydrophobicContact CB-CB 4.5Å; N256-E259 PolarHBondContact O-N 3.43Å; E259-L261 PolarHBondContact O-N 3.32Å; E259-M262 PolarHBondContact O-N 2.85Å; E259-E263 WeakPolarHBondContact O-CB 2.77Å; E259-E263 PolarHBondContact O-N 2.99Å
260A95.1Very high92.1Very high24 Ų2455.9 Ų55.920%0.19827%0.269CS..Hα-helixtrans-61.3-41.5176.400000112.3L207 N256 C264L207-A260 HydrophobicContact CD1-CB 4.4Å; N256-A260 WeakPolarHBondContact O-CB 3.22Å; N256-A260 PolarHBondContact O-N 3.36Å; A260-C264 WeakPolarHBondContact O-CB 3.42Å; A260-C264 PolarHBondContact O-N 3.33Å
261L96.2Very high92.2Very high0 Ų058.1 Ų58.10%028%0.283CS..Hα-helixtrans-63.9-45.3173.2-177.471.9000111.4Y206 L207 T210 A245 L249 S257 V258 E259 E263 C264 C265Y206-L261 HydrophobicContact CD1-CD1 3.81Å; Y206-L261 HydrophobicContact CE1-CD1 3.71Å; Y206-L261 HydrophobicContact CE1-CD2 3.74Å; Y206-L261 HydrophobicContact CE1-CG 4.37Å; L207-L261 VanDerWaalsContact CD2-CA 3.4Å; L207-L261 HydrophobicContact CD2-CB 3.87Å; L207-L261 HydrophobicContact CD2-CD1 3.69Å; L207-L261 HydrophobicContact CD2-CG 4.41Å; T210-L261 HydrophobicContact CG2-CD1 3.78Å; A245-L261 HydrophobicContact CB-CD2 3.4Å; L249-L261 HydrophobicContact CD1-CB 3.86Å; L249-L261 HydrophobicContact CD1-CD2 4.05Å; L249-L261 HydrophobicContact CD1-CG 4.46Å; S257-L261 WeakPolarHBondContact O-CB 3.11Å; S257-L261 PolarHBondContact O-N 3.18Å; V258-L261 PolarHBondContact O-N 2.99Å; E259-L261 PolarHBondContact O-N 3.32Å; L261-E263 VanDerWaalsContact C-N 3.32Å; L261-E263 PolarHBondContact O-N 3.41Å; L261-C264 WeakPolarHBondContact O-CB 3.43Å; L261-C264 PolarHBondContact O-N 3.22Å; L261-C265 WeakPolarHBondContact O-CB 3.28Å; L261-C265 PolarHBondContact O-N 3.12Å; L261-C265 PolarHBondContact O-SG 2.84Å; L261-C265 VanDerWaalsContact O-SG 3.34Å
262M95.9Very high92.3Very high31 Ų3158.4 Ų58.415%0.15329%0.288CS..Hα-helixtrans-63.6-39.6-179.3-69.7-49.5-64.900111.6L238 E242 V258 E259 C265 V266L238-M262 HydrophobicContact CB-CE 4.21Å; L238-M262 HydrophobicContact CD2-CE 4.04Å; E242-M262 HydrophobicContact CB-CE 4.05Å; E242-M262 HydrophobicContact CB-SD 3.68Å; E242-M262 HydrophobicContact CG-SD 4.26Å; V258-M262 HydrophobicContact CG1-CG 4.46Å; V258-M262 VanDerWaalsContact O-CG 3.27Å; V258-M262 WeakPolarHBondContact O-CG 3.47Å; V258-M262 PolarHBondContact O-N 3.24Å; E259-M262 PolarHBondContact O-N 2.85Å; M262-C265 PolarHBondContact O-N 3.39Å; M262-V266 WeakPolarHBondContact O-CB 3.36Å; M262-V266 VanDerWaalsContact O-CG2 3.23Å; M262-V266 WeakPolarHBondContact O-CG2 3.06Å; M262-V266 PolarHBondContact O-N 3.31Å
263E95.2Very high92.7Very high131 Ų13154.4 Ų54.461%0.61227%0.273SS*.Hα-helixtrans-61.2-46.2172.6-173.6178.5176.400111.5E259 L261 C265 V266 N267E259-E263 WeakPolarHBondContact O-CB 2.77Å; E259-E263 PolarHBondContact O-N 2.99Å; L261-E263 VanDerWaalsContact C-N 3.32Å; L261-E263 PolarHBondContact O-N 3.41Å; E263-C265 PolarHBondContact O-N 2.96Å; E263-V266 PolarHBondContact O-N 2.88Å; E263-N267 WeakPolarHBondContact O-CB 3.42Å; E263-N267 PolarHBondContact O-N 2.75Å; E263-N267 PolarHBondContact O-ND2 3.39Å
264C95.6Very high93.6Very high20 Ų2045.4 Ų45.414%0.13524%0.241CC..Hα-helixtrans-57.8-46.3174.7-178.80000112.1L207 A260 L261 N267 A268L207-C264 HydrophobicContact CD2-CB 4.21Å; A260-C264 WeakPolarHBondContact O-CB 3.42Å; A260-C264 PolarHBondContact O-N 3.33Å; L261-C264 WeakPolarHBondContact O-CB 3.43Å; L261-C264 PolarHBondContact O-N 3.22Å; C264-N267 PolarHBondContact O-N 3.28Å; C264-A268 WeakPolarHBondContact O-CB 2.92Å; C264-A268 PolarHBondContact O-N 2.94Å
265C96.1Very high94.5Very high0 Ų043.9 Ų43.90%023%0.234CC..Hα-helixtrans-65.6-43.3178.5-72.30000111.9T210 L238 L261 M262 E263 N267 A268 L269T210-C265 VanDerWaalsContact CG2-SG 3.56Å; L238-C265 HydrophobicContact CD2-CB 3.69Å; L261-C265 WeakPolarHBondContact O-CB 3.28Å; L261-C265 PolarHBondContact O-N 3.12Å; L261-C265 PolarHBondContact O-SG 2.84Å; L261-C265 VanDerWaalsContact O-SG 3.34Å; M262-C265 PolarHBondContact O-N 3.39Å; E263-C265 PolarHBondContact O-N 2.96Å; C265-N267 VanDerWaalsContact C-N 3.3Å; C265-N267 PolarHBondContact O-N 3.47Å; C265-A268 PolarHBondContact O-N 3Å; C265-L269 VanDerWaalsContact O-CB 3.24Å; C265-L269 WeakPolarHBondContact O-CB 3.42Å; C265-L269 PolarHBondContact O-N 2.89Å
266V95.9Very high94.9Very high13 Ų1346.1 Ų46.18%0.07925%0.247CC..Hα-helixtrans-61.3-41.6175.5168.70000110.3L238 M262 E263 V270 T271 K302 V303L238-V266 HydrophobicContact CD1-CG2 4.47Å; L238-V266 HydrophobicContact CD2-CG2 3.89Å; M262-V266 WeakPolarHBondContact O-CB 3.36Å; M262-V266 VanDerWaalsContact O-CG2 3.23Å; M262-V266 WeakPolarHBondContact O-CG2 3.06Å; M262-V266 PolarHBondContact O-N 3.31Å; E263-V266 PolarHBondContact O-N 2.88Å; V266-V270 HydrophobicContact CG1-CB 4.31Å; V266-V270 CarbonylContact O-C 3.5Å; V266-V270 WeakPolarHBondContact O-CA 3.46Å; V266-V270 VanDerWaalsContact O-CB 3.29Å; V266-V270 WeakPolarHBondContact O-CB 3.23Å; V266-V270 PolarHBondContact O-N 3.4Å; V266-T271 PolarHBondContact O-N 3.3Å; V266-K302 HydrophobicContact CG1-CB 4.09Å; V266-K302 HydrophobicContact CG2-CB 4.06Å; V266-K302 HydrophobicContact CG2-CD 4.16Å; V266-V303 HydrophobicContact CG1-CG2 3.85Å
267N95.4Very high95Very high66 Ų6641.7 Ų41.735%0.35322%0.223SC..Hα-helixtrans-63.6-44.3176.8-75.8-30.3000112.6E263 C264 C265 T271 S272E263-N267 WeakPolarHBondContact O-CB 3.42Å; E263-N267 PolarHBondContact O-N 2.75Å; E263-N267 PolarHBondContact O-ND2 3.39Å; C264-N267 PolarHBondContact O-N 3.28Å; C265-N267 VanDerWaalsContact C-N 3.3Å; C265-N267 PolarHBondContact O-N 3.47Å; N267-T271 PolarHBondContact OD1-OG1 3.02Å; N267-S272 PolarHBondContact O-N 3.45Å; N267-S272 PolarHBondContact O-OG 3.46Å
268A95.1Very high95.1Very high8 Ų842.5 Ų42.57%0.06623%0.228CC..Hα-helixtrans-73.1-38.4-179.700000113.7C264 C265 F273C264-A268 WeakPolarHBondContact O-CB 2.92Å; C264-A268 PolarHBondContact O-N 2.94Å; C265-A268 PolarHBondContact O-N 3Å; A268-F273 WeakPolarHBondContact O-CE2 3.36Å
269L95.6Very high95.1Very high0 Ų045.3 Ų45.30%025%0.253CS..Hα-helixtrans-99.1-19.7-173.2-71.1166000114.5Y214 A218 Y230 Y233 A234 K237 L238 C265Y214-L269 HydrophobicContact CD1-CD1 4.13Å; Y214-L269 HydrophobicContact CD1-CD2 3.6Å; Y214-L269 HydrophobicContact CD1-CG 4.08Å; Y214-L269 HydrophobicContact CD2-CD1 4.25Å; Y214-L269 HydrophobicContact CD2-CG 4.44Å; Y214-L269 HydrophobicContact CE1-CD1 4.14Å; Y214-L269 HydrophobicContact CE1-CD2 4.17Å; Y214-L269 HydrophobicContact CE2-CD1 4.28Å; Y214-L269 HydrophobicContact CG-CD1 4.17Å; Y214-L269 HydrophobicContact CG-CD2 3.96Å; Y214-L269 HydrophobicContact CG-CG 3.99Å; A218-L269 HydrophobicContact CB-CD2 4.08Å; Y230-L269 WeakPolarHBondContact CE1-O 3.14Å; Y230-L269 PolarHBondContact OH-O 3.36Å; Y233-L269 HydrophobicContact CE1-CD2 4.04Å; A234-L269 HydrophobicContact CB-CB 4.42Å; K237-L269 HydrophobicContact CB-CD1 3.97Å; L238-L269 HydrophobicContact CD2-CD1 4.24Å; L238-L269 HydrophobicContact CG-CD1 4.31Å; C265-L269 VanDerWaalsContact O-CB 3.24Å; C265-L269 WeakPolarHBondContact O-CB 3.42Å; C265-L269 PolarHBondContact O-N 2.89Å
270V95.5Very high95.1Very high0 Ų042.9 Ų42.90%024%0.241CC..THydrogen-bonded Turntrans-125.4-59.2-173.4-167.60000110.4L238 V266 S272 F273 K274 L299 M300 V303L238-V270 HydrophobicContact CD1-CG2 4.03Å; V266-V270 HydrophobicContact CG1-CB 4.31Å; V266-V270 CarbonylContact O-C 3.5Å; V266-V270 WeakPolarHBondContact O-CA 3.46Å; V266-V270 VanDerWaalsContact O-CB 3.29Å; V266-V270 WeakPolarHBondContact O-CB 3.23Å; V266-V270 PolarHBondContact O-N 3.4Å; V270-S272 VanDerWaalsContact C-N 3.31Å; V270-S272 PolarHBondContact O-N 3Å; V270-F273 CarbonylContact O-C 3.54Å; V270-F273 PolarHBondContact O-N 3.32Å; V270-K274 PolarHBondContact O-N 3.44Å; V270-L299 HydrophobicContact CG1-CB 4.09Å; V270-L299 HydrophobicContact CG2-CD2 4.15Å; V270-M300 HydrophobicContact CG1-CE 3.31Å; V270-V303 HydrophobicContact CB-CG2 3.98Å; V270-V303 HydrophobicContact CG1-CG2 3.55Å
271T95Very high95.2Very high51 Ų5141.8 Ų41.831%0.31323%0.232SC..G310 helixtrans-57.9-43-177.1-51.90000111.7V266 N267 F273 K274 V303V266-T271 PolarHBondContact O-N 3.3Å; N267-T271 PolarHBondContact OD1-OG1 3.02Å; T271-F273 PolarHBondContact O-N 3.16Å; T271-K274 VanDerWaalsContact O-CB 3.28Å; T271-K274 WeakPolarHBondContact O-CB 3.3Å; T271-K274 PolarHBondContact O-N 2.97Å; T271-V303 HydrophobicContact CG2-CG1 4.4Å
272S93.6Very high95.1Very high85 Ų8545.5 Ų45.559%0.59425%0.249SC*.G310 helixtrans-62.6-21.5179-62.90000114.3N267 V270N267-S272 PolarHBondContact O-N 3.45Å; N267-S272 PolarHBondContact O-OG 3.46Å; V270-S272 VanDerWaalsContact C-N 3.31Å; V270-S272 PolarHBondContact O-N 3Å
273F94.6Very high95.1Very high24 Ų2444.9 Ų44.911%0.10525%0.251CS..G310 helixtrans-11913.3-178.5-57-83.4000112.4A218 P219 L222 Y230 A268 V270 T271 E275 T276 I277A218-F273 HydrophobicContact CB-CE2 3.6Å; A218-F273 HydrophobicContact CB-CZ 3.76Å; P219-F273 HydrophobicContact CB-CE1 4.37Å; P219-F273 HydrophobicContact CB-CZ 4.32Å; P219-F273 HydrophobicContact CG-CE1 4.29Å; P219-F273 HydrophobicContact CG-CZ 3.81Å; L222-F273 HydrophobicContact CD2-CD1 3.4Å; L222-F273 HydrophobicContact CD2-CE1 3.78Å; L222-F273 HydrophobicContact CD2-CG 4.31Å; Y230-F273 HydrophobicContact CE1-CB 4.01Å; Y230-F273 HydrophobicContact CE1-CD2 4.05Å; Y230-F273 HydrophobicContact CE1-CG 4.05Å; Y230-F273 AromaticContact CZ-CD2 3.64Å; Y230-F273 AromaticContact CZ-CE2 3.97Å; Y230-F273 AromaticContact CZ-CG 3.98Å; Y230-F273 WeakPolarHBondContact OH-CD2 3.33Å; Y230-F273 WeakPolarHBondContact OH-CE2 3.37Å; A268-F273 WeakPolarHBondContact O-CE2 3.36Å; V270-F273 CarbonylContact O-C 3.54Å; V270-F273 PolarHBondContact O-N 3.32Å; T271-F273 PolarHBondContact O-N 3.16Å; F273-E275 VanDerWaalsContact C-N 3.35Å; F273-E275 PolarHBondContact O-N 3.27Å; F273-T276 PolarHBondContact O-N 3.22Å; F273-T276 VanDerWaalsContact O-N 3.17Å; F273-I277 HydrophobicContact CB-CD1 4.25Å; F273-I277 HydrophobicContact CB-CG1 4.49Å; F273-I277 WeakPolarHBondContact O-CG1 3.38Å; F273-I277 PolarHBondContact O-N 3.32Å
274K94.1Very high95.1Very high51 Ų5138.6 Ų38.622%0.22222%0.222CC..Hα-helixtrans-51.3-51.8-175.5172.5179.6178175.50111.7V270 T271 T276 I277 L278 M300 V303 N305V270-K274 PolarHBondContact O-N 3.44Å; T271-K274 VanDerWaalsContact O-CB 3.28Å; T271-K274 WeakPolarHBondContact O-CB 3.3Å; T271-K274 PolarHBondContact O-N 2.97Å; K274-T276 PolarHBondContact O-N 3.47Å; K274-I277 PolarHBondContact O-N 3.5Å; K274-L278 HydrophobicContact CD-CD1 4.34Å; K274-L278 HydrophobicContact CG-CD1 3.6Å; K274-L278 HydrophobicContact CG-CG 4.38Å; K274-L278 WeakPolarHBondContact O-CB 3.4Å; K274-L278 VanDerWaalsContact O-CG 3.24Å; K274-L278 WeakPolarHBondContact O-CG 3.44Å; K274-L278 PolarHBondContact O-N 3.15Å; K274-M300 HydrophobicContact CG-SD 4.33Å; K274-V303 HydrophobicContact CD-CG1 4.34Å; K274-N305 PolarHBondContact NZ-O 2.6Å
275E94.7Very high95.1Very high169 Ų16937.7 Ų37.779%0.7922%0.216SC*.Hα-helixtrans-62.3-42.8-177.7-63.8-175.8169.600112F273 L278 A279F273-E275 VanDerWaalsContact C-N 3.35Å; F273-E275 PolarHBondContact O-N 3.27Å; E275-L278 PolarHBondContact O-N 3.06Å; E275-A279 WeakPolarHBondContact O-CB 3.32Å; E275-A279 PolarHBondContact O-N 2.92Å
276T94.7Very high95Very high64 Ų6443.2 Ų43.239%0.39324%0.24SC..Hα-helixtrans-66.2-38.8178.6-47.10000112.4L222 V227 F273 K274L222-T276 HydrophobicContact CD2-CG2 4.24Å; V227-T276 HydrophobicContact CG2-CG2 3.9Å; F273-T276 PolarHBondContact O-N 3.22Å; F273-T276 VanDerWaalsContact O-N 3.17Å; K274-T276 PolarHBondContact O-N 3.47Å
277I95.1Very high95Very high1 Ų148.9 Ų48.91%0.00526%0.26CS..Hα-helixtrans-66.6-48.4175.9-66.4166.5000110V227 Y230 M231 F273 K274 A279 E280 M296 M300V227-I277 HydrophobicContact CG1-CG1 4.3Å; Y230-I277 HydrophobicContact CD1-CD1 4.37Å; Y230-I277 HydrophobicContact CD1-CG1 4.49Å; Y230-I277 HydrophobicContact CE1-CD1 4.18Å; M231-I277 HydrophobicContact CG-CG1 4.4Å; M231-I277 HydrophobicContact CG-CG2 4.1Å; M231-I277 HydrophobicContact SD-CG2 3.68Å; F273-I277 HydrophobicContact CB-CD1 4.25Å; F273-I277 HydrophobicContact CB-CG1 4.49Å; F273-I277 WeakPolarHBondContact O-CG1 3.38Å; F273-I277 PolarHBondContact O-N 3.32Å; K274-I277 PolarHBondContact O-N 3.5Å; I277-A279 VanDerWaalsContact C-N 3.29Å; I277-A279 PolarHBondContact O-N 2.94Å; I277-E280 PolarHBondContact O-N 3.27Å; I277-M296 HydrophobicContact CG2-CE 3.93Å; I277-M296 HydrophobicContact CG2-CG 3.95Å; I277-M296 HydrophobicContact CG2-SD 4.44Å; I277-M296 WeakPolarHBondContact O-CE 3.46Å; I277-M300 HydrophobicContact CB-CE 4.29Å; I277-M300 HydrophobicContact CD1-CE 3.95Å; I277-M300 HydrophobicContact CG2-CE 3.98Å
278L94.9Very high94.9Very high18 Ų1849.8 Ų49.89%0.09426%0.264CS..Hα-helixtrans-66.6-28.1-177.7-70.7172.4000113.1K274 E275 E280 C281 M300 P309 M310K274-L278 HydrophobicContact CD-CD1 4.34Å; K274-L278 HydrophobicContact CG-CD1 3.6Å; K274-L278 HydrophobicContact CG-CG 4.38Å; K274-L278 WeakPolarHBondContact O-CB 3.4Å; K274-L278 VanDerWaalsContact O-CG 3.24Å; K274-L278 WeakPolarHBondContact O-CG 3.44Å; K274-L278 PolarHBondContact O-N 3.15Å; E275-L278 PolarHBondContact O-N 3.06Å; L278-E280 PolarHBondContact O-N 3.16Å; L278-E280 VanDerWaalsContact O-N 3.13Å; L278-C281 WeakPolarHBondContact O-CB 3.36Å; L278-C281 PolarHBondContact O-N 3.31Å; L278-M300 HydrophobicContact CD1-SD 4.4Å; L278-M300 HydrophobicContact CD2-CG 4.01Å; L278-M300 HydrophobicContact CD2-SD 3.93Å; L278-M300 HydrophobicContact CG-SD 4.02Å; L278-P309 HydrophobicContact CD1-CB 3.91Å; L278-P309 HydrophobicContact CD1-CG 3.73Å; L278-P309 HydrophobicContact CD2-CB 4.26Å; L278-M310 HydrophobicContact CD2-CG 3.62Å; L278-M310 HydrophobicContact CD2-SD 4.45Å
279A95Very high94.9Very high78 Ų7851.5 Ų51.565%0.64527%0.271SS*.THydrogen-bonded Turntrans-57.9-26.1175.400000113.5E275 I277E275-A279 WeakPolarHBondContact O-CB 3.32Å; E275-A279 PolarHBondContact O-N 2.92Å; I277-A279 VanDerWaalsContact C-N 3.29Å; I277-A279 PolarHBondContact O-N 2.94Å
280E94.6Very high94.9Very high67 Ų6752.7 Ų52.731%0.31328%0.278SS..THydrogen-bonded Turntrans-84.2-15.8176-68.4-67.6144.600113.4V227 I277 L278 Q282 G283 M284 M296V227-E280 HydrophobicContact CB-CG 3.93Å; V227-E280 HydrophobicContact CG1-CG 3.87Å; V227-E280 HydrophobicContact CG2-CG 4.1Å; I277-E280 PolarHBondContact O-N 3.27Å; L278-E280 PolarHBondContact O-N 3.16Å; L278-E280 VanDerWaalsContact O-N 3.13Å; E280-Q282 PolarHBondContact O-N 2.94Å; E280-G283 PolarHBondContact O-N 3.31Å; E280-G283 VanDerWaalsContact O-N 3.17Å; E280-M284 HydrophobicContact CB-CE 3.73Å; E280-M284 HydrophobicContact CG-CE 4.48Å; E280-M284 WeakPolarHBondContact O-CG 3.42Å; E280-M284 PolarHBondContact O-N 3.38Å; E280-M296 HydrophobicContact CB-CE 4.28Å
281C96Very high94.9Very high0 Ų060.9 Ų60.90%032%0.316CS..Hα-helixtrans-58.5-54.2-170.1-169.60000111.8L278 G283 M284 I285 M296 D313L278-C281 WeakPolarHBondContact O-CB 3.36Å; L278-C281 PolarHBondContact O-N 3.31Å; C281-G283 PolarHBondContact O-N 2.9Å; C281-M284 PolarHBondContact O-N 3.47Å; C281-M284 VanDerWaalsContact O-N 3.08Å; C281-I285 WeakPolarHBondContact O-CG1 3.33Å; C281-I285 PolarHBondContact O-N 2.9Å; C281-M296 HydrophobicContact CB-CE 4.21Å; C281-M296 HydrophobicContact CB-SD 3.56Å; C281-M296 VanDerWaalsContact CB-SD 3.56Å; C281-M296 VanDerWaalsContact SG-SD 3.68Å; C281-D313 WeakPolarHBondContact CB-OD2 3.4Å
282Q95Very high94.9Very high78 Ų7861.6 Ų61.636%0.36432%0.315SS..Hα-helixtrans-54.2-40.1178.2-163-165.447.600112.7E280 K286 D313E280-Q282 PolarHBondContact O-N 2.94Å; Q282-K286 WeakPolarHBondContact O-CG 3.47Å; Q282-K286 PolarHBondContact O-N 2.74Å; Q282-K286 VanDerWaalsContact O-N 3.11Å; Q282-D313 PolarHBondContact N-OD2 2.79Å
283G94.9Very high95Very high18 Ų1857.5 Ų57.519%0.18629%0.287CS..Hα-helixtrans-67.5-43.6177.600000112.7E280 C281 K286 R287E280-G283 PolarHBondContact O-N 3.31Å; E280-G283 VanDerWaalsContact O-N 3.17Å; C281-G283 PolarHBondContact O-N 2.9Å; G283-K286 PolarHBondContact O-N 2.88Å; G283-R287 VanDerWaalsContact C-CZ 3.5Å; G283-R287 WeakPolarHBondContact O-CG 3.44Å; G283-R287 VanDerWaalsContact O-CZ 3.3Å; G283-R287 PolarHBondContact O-N 2.84Å; G283-R287 VanDerWaalsContact O-N 3.07Å
284M95.7Very high95.1Very high0 Ų059.1 Ų59.10%030%0.295CS..Hα-helixtrans-64.5-40.1177.3-68.4-174.9-172.600112.2Q228 M231 E280 C281 R287 N288 E289 K292 L293 M296Q228-M284 HydrophobicContact CG-CE 3.73Å; M231-M284 HydrophobicContact CE-CE 3.51Å; M231-M284 HydrophobicContact CE-SD 4.17Å; E280-M284 HydrophobicContact CB-CE 3.73Å; E280-M284 HydrophobicContact CG-CE 4.48Å; E280-M284 WeakPolarHBondContact O-CG 3.42Å; E280-M284 PolarHBondContact O-N 3.38Å; C281-M284 PolarHBondContact O-N 3.47Å; C281-M284 VanDerWaalsContact O-N 3.08Å; M284-R287 PolarHBondContact O-N 2.67Å; M284-N288 PolarHBondContact O-N 3.43Å; M284-N288 VanDerWaalsContact O-N 3.09Å; M284-E289 HydrophobicContact CB-CB 4.33Å; M284-E289 WeakPolarHBondContact CG-OE2 3.27Å; M284-E289 PolarHBondContact O-N 3.09Å; M284-K292 HydrophobicContact CE-CB 4.37Å; M284-K292 HydrophobicContact SD-CB 3.75Å; M284-L293 HydrophobicContact CB-CD2 3.62Å; M284-L293 HydrophobicContact CB-CG 3.94Å; M284-M296 HydrophobicContact CE-CE 3.97Å; M284-M296 HydrophobicContact SD-CE 3.65Å
285I96.1Very high95.2Very high1 Ų158 Ų581%0.00529%0.291CS..Hα-helixtrans-60.5-51.5174.2-67.3176.5000109.9C281 R287 N288 L293 D313 L314 H317 L354C281-I285 WeakPolarHBondContact O-CG1 3.33Å; C281-I285 PolarHBondContact O-N 2.9Å; I285-R287 VanDerWaalsContact C-N 3.26Å; I285-R287 PolarHBondContact O-N 3.19Å; I285-N288 PolarHBondContact O-N 2.88Å; I285-L293 HydrophobicContact CG1-CD1 4.05Å; I285-L293 HydrophobicContact CG1-CD2 3.74Å; I285-D313 HydrophobicContact CD1-CB 3.84Å; I285-L314 HydrophobicContact CD1-CB 4.15Å; I285-L314 HydrophobicContact CG2-CD1 4.31Å; I285-H317 HydrophobicContact CG2-CB 3.59Å; I285-H317 WeakPolarHBondContact CG2-CD2 3.47Å; I285-H317 VanDerWaalsContact CG2-CG 3.41Å; I285-L354 HydrophobicContact CG2-CD2 4.23Å
286K94.3Very high95.3Very high116 Ų11650 Ų5050%0.50425%0.253SS..Hα-helixtrans-59.5-34.5180-75.4172.7-178.2169.80113.4Q282 G283Q282-K286 WeakPolarHBondContact O-CG 3.47Å; Q282-K286 PolarHBondContact O-N 2.74Å; Q282-K286 VanDerWaalsContact O-N 3.11Å; G283-K286 PolarHBondContact O-N 2.88Å
287R95Very high95.4Very high132 Ų13247.8 Ų47.850%0.49824%0.239SC..THydrogen-bonded Turntrans-880.1178.7-68-175.4-60.2-94.2-1.6113.9G283 M284 I285 E289G283-R287 VanDerWaalsContact C-CZ 3.5Å; G283-R287 WeakPolarHBondContact O-CG 3.44Å; G283-R287 VanDerWaalsContact O-CZ 3.3Å; G283-R287 PolarHBondContact O-N 2.84Å; G283-R287 VanDerWaalsContact O-N 3.07Å; M284-R287 PolarHBondContact O-N 2.67Å; I285-R287 VanDerWaalsContact C-N 3.26Å; I285-R287 PolarHBondContact O-N 3.19Å; R287-E289 VanDerWaalsContact C-N 3.3Å; R287-E289 HydrophobicContact CB-CG 3.84Å; R287-E289 IonicContact CZ-OE2 3.8Å; R287-E289 IonicContact NE-OE1 2.7Å; R287-E289 IonicContact NE-OE2 3.33Å; R287-E289 PolarHBondContact NE-OE2 3.3Å; R287-E289 IonicContact NH2-OE2 3.13Å; R287-E289 PolarHBondContact NH2-OE2 2.87Å; R287-E289 PolarHBondContact O-N 3.43Å
288N93.4Very high95.5Very high85 Ų8549.3 Ų49.346%0.45525%0.249SC..THydrogen-bonded Turntrans56.539.9-177.7-163.261.2000113.2M284 I285 T290M284-N288 PolarHBondContact O-N 3.43Å; M284-N288 VanDerWaalsContact O-N 3.09Å; I285-N288 PolarHBondContact O-N 2.88Å; N288-T290 VanDerWaalsContact C-N 3.26Å; N288-T290 PolarHBondContact O-N 3.47Å
289E95.1Very high95.5Very high43 Ų4348.5 Ų48.520%0.20125%0.245CC..  trans-82.364.3-179.5-63.2-178.3120.700111.4M284 R287 E291 K292 L293M284-E289 HydrophobicContact CB-CB 4.33Å; M284-E289 WeakPolarHBondContact CG-OE2 3.27Å; M284-E289 PolarHBondContact O-N 3.09Å; R287-E289 VanDerWaalsContact C-N 3.3Å; R287-E289 HydrophobicContact CB-CG 3.84Å; R287-E289 IonicContact CZ-OE2 3.8Å; R287-E289 IonicContact NE-OE1 2.7Å; R287-E289 IonicContact NE-OE2 3.33Å; R287-E289 PolarHBondContact NE-OE2 3.3Å; R287-E289 IonicContact NH2-OE2 3.13Å; R287-E289 PolarHBondContact NH2-OE2 2.87Å; R287-E289 PolarHBondContact O-N 3.43Å; E289-E291 PolarHBondContact O-N 3.03Å; E289-K292 HydrophobicContact CB-CB 4.25Å; E289-K292 HydrophobicContact CB-CD 4.03Å; E289-K292 HydrophobicContact CB-CG 4.3Å; E289-K292 HydrophobicContact CG-CD 4.43Å; E289-K292 PolarHBondContact O-N 2.74Å; E289-K292 IonicContact OE1-NZ 3.91Å; E289-K292 PolarHBondContact OE1-NZ 2.91Å; E289-L293 PolarHBondContact O-N 2.94Å
290T95.5Very high95.6Very high26 Ų2644.8 Ų44.816%0.1621%0.214CC..Hα-helixtrans-56.3-42.2-168.5540000114.3N288 K292 L293 H294 L354 E357 A358N288-T290 VanDerWaalsContact C-N 3.26Å; N288-T290 PolarHBondContact O-N 3.47Å; T290-K292 VanDerWaalsContact C-N 3.31Å; T290-K292 PolarHBondContact O-N 2.7Å; T290-L293 PolarHBondContact O-N 2.96Å; T290-H294 WeakPolarHBondContact O-CB 3.39Å; T290-H294 PolarHBondContact O-N 3.32Å; T290-L354 HydrophobicContact CG2-CD1 4.09Å; T290-E357 HydrophobicContact CG2-CB 3.73Å; T290-A358 HydrophobicContact CG2-CB 4.29Å
291E95.5Very high95.7Very high171 Ų17145.2 Ų45.280%0.79922%0.219SC*.Hα-helixtrans-61.3-38.4176.8-64.6-177.5174.700112.8E289 H294 L295E289-E291 PolarHBondContact O-N 3.03Å; E291-H294 PolarHBondContact O-N 2.92Å; E291-L295 PolarHBondContact O-N 2.94Å
292K94.9Very high95.5Very high66 Ų6650.5 Ų50.529%0.28724%0.242SC..Hα-helixtrans-74.4-37.9179.9-57.4-178.3-170.21740110.9Q228 M284 E289 T290 H294 L295 M296Q228-K292 VanDerWaalsContact OE1-CD 3.31Å; Q228-K292 VanDerWaalsContact OE1-CE 3.22Å; M284-K292 HydrophobicContact CE-CB 4.37Å; M284-K292 HydrophobicContact SD-CB 3.75Å; E289-K292 HydrophobicContact CB-CB 4.25Å; E289-K292 HydrophobicContact CB-CD 4.03Å; E289-K292 HydrophobicContact CB-CG 4.3Å; E289-K292 HydrophobicContact CG-CD 4.43Å; E289-K292 PolarHBondContact O-N 2.74Å; E289-K292 IonicContact OE1-NZ 3.91Å; E289-K292 PolarHBondContact OE1-NZ 2.91Å; T290-K292 VanDerWaalsContact C-N 3.31Å; T290-K292 PolarHBondContact O-N 2.7Å; K292-H294 VanDerWaalsContact C-N 3.32Å; K292-L295 PolarHBondContact O-N 3.01Å; K292-M296 WeakPolarHBondContact O-CB 3.48Å; K292-M296 PolarHBondContact O-N 3.41Å
293L96.7Very high95.5Very high0 Ų047.3 Ų47.30%023%0.227CC..Hα-helixtrans-64.2-38.3173.2-70.7169.1000111.7M284 I285 E289 T290 L295 M296 F297 L354 A358 F359M284-L293 HydrophobicContact CB-CD2 3.62Å; M284-L293 HydrophobicContact CB-CG 3.94Å; I285-L293 HydrophobicContact CG1-CD1 4.05Å; I285-L293 HydrophobicContact CG1-CD2 3.74Å; E289-L293 PolarHBondContact O-N 2.94Å; T290-L293 PolarHBondContact O-N 2.96Å; L293-L295 VanDerWaalsContact C-N 3.35Å; L293-M296 PolarHBondContact O-N 3.41Å; L293-F297 WeakPolarHBondContact O-CB 3.42Å; L293-F297 PolarHBondContact O-N 3.3Å; L293-L354 HydrophobicContact CD1-CD1 4.12Å; L293-A358 HydrophobicContact CB-CB 3.71Å; L293-A358 HydrophobicContact CD1-CB 3.94Å; L293-A358 HydrophobicContact CG-CB 4.5Å; L293-F359 HydrophobicContact CB-CE1 4.18Å; L293-F359 HydrophobicContact CB-CZ 4.27Å; L293-F359 HydrophobicContact CD1-CZ 4.44Å; L293-F359 HydrophobicContact CD2-CZ 4.42Å
294H96.6Very high95.3Very high58 Ų5851.4 Ų51.427%0.26925%0.251SS..Hα-helixtrans-62-43.7175.7-174.460.7000112T290 E291 K292 F297 S298 A358 Q360T290-H294 WeakPolarHBondContact O-CB 3.39Å; T290-H294 PolarHBondContact O-N 3.32Å; E291-H294 PolarHBondContact O-N 2.92Å; K292-H294 VanDerWaalsContact C-N 3.32Å; H294-F297 PolarHBondContact O-N 3.41Å; H294-S298 PolarHBondContact O-N 3.23Å; H294-A358 WeakPolarHBondContact CA-O 3.47Å; H294-A358 WeakPolarHBondContact CB-O 3.28Å; H294-A358 PolarHBondContact N-O 3.11Å; H294-A358 PolarHBondContact ND1-O 3.33Å; H294-Q360 PolarHBondContact CE1-NE2 3.45Å; H294-Q360 PolarHBondContact NE2-NE2 3.17Å
295L96.1Very high95Very high28 Ų2856.2 Ų56.215%0.14728%0.277CS..Hα-helixtrans-65.5-40.8173.7-179.463.5000112.5M231 K232 D235 E291 K292 L293 F297 S298 L299M231-L295 HydrophobicContact CB-CD2 3.77Å; M231-L295 HydrophobicContact CB-CG 4.08Å; K232-L295 HydrophobicContact CB-CD2 4.3Å; K232-L295 HydrophobicContact CG-CD2 3.5Å; K232-L295 VanDerWaalsContact CG-CD2 3.5Å; D235-L295 HydrophobicContact CB-CD1 3.65Å; E291-L295 PolarHBondContact O-N 2.94Å; K292-L295 PolarHBondContact O-N 3.01Å; L293-L295 VanDerWaalsContact C-N 3.35Å; L295-F297 VanDerWaalsContact C-N 3.32Å; L295-F297 PolarHBondContact O-N 3.02Å; L295-S298 PolarHBondContact O-N 3.25Å; L295-S298 PolarHBondContact O-OG 3.4Å; L295-L299 WeakPolarHBondContact O-CG 3.44Å; L295-L299 PolarHBondContact O-N 3.33Å
296M97Very high94.9Very high0 Ų056.2 Ų56.20%028%0.276CS..Hα-helixtrans-61.4-44.1175-175.9179.3-72.800110.9M231 I277 E280 C281 M284 K292 L293 L299 M300 M310M231-M296 HydrophobicContact CE-CB 4.47Å; M231-M296 HydrophobicContact CE-CE 4.2Å; M231-M296 HydrophobicContact SD-CB 3.73Å; M231-M296 HydrophobicContact SD-CE 3.93Å; M231-M296 HydrophobicContact SD-CG 4.09Å; I277-M296 HydrophobicContact CG2-CE 3.93Å; I277-M296 HydrophobicContact CG2-CG 3.95Å; I277-M296 HydrophobicContact CG2-SD 4.44Å; I277-M296 WeakPolarHBondContact O-CE 3.46Å; E280-M296 HydrophobicContact CB-CE 4.28Å; C281-M296 HydrophobicContact CB-CE 4.21Å; C281-M296 HydrophobicContact CB-SD 3.56Å; C281-M296 VanDerWaalsContact CB-SD 3.56Å; C281-M296 VanDerWaalsContact SG-SD 3.68Å; M284-M296 HydrophobicContact CE-CE 3.97Å; M284-M296 HydrophobicContact SD-CE 3.65Å; K292-M296 WeakPolarHBondContact O-CB 3.48Å; K292-M296 PolarHBondContact O-N 3.41Å; L293-M296 PolarHBondContact O-N 3.41Å; M296-L299 PolarHBondContact O-N 3.02Å; M296-M300 HydrophobicContact CG-CG 4.18Å; M296-M300 WeakPolarHBondContact O-CB 3.1Å; M296-M300 VanDerWaalsContact O-CG 3.3Å; M296-M300 WeakPolarHBondContact O-CG 3.39Å; M296-M300 PolarHBondContact O-N 3.33Å; M296-M310 HydrophobicContact CB-CE 4.1Å; M296-M310 HydrophobicContact CG-CE 3.78Å; M296-M310 HydrophobicContact CG-SD 3.98Å; M296-M310 HydrophobicContact SD-CE 3.92Å; M296-M310 HydrophobicContact SD-SD 4.32Å
297F96.9Very high94.9Very high18 Ų1851.5 Ų51.58%0.07926%0.257CS..Hα-helixtrans-60.7-46.8177169.8-121.9000111.5L293 H294 L295 L299 M300 D301 I307 M310 F359 D362 F365L293-F297 WeakPolarHBondContact O-CB 3.42Å; L293-F297 PolarHBondContact O-N 3.3Å; H294-F297 PolarHBondContact O-N 3.41Å; L295-F297 VanDerWaalsContact C-N 3.32Å; L295-F297 PolarHBondContact O-N 3.02Å; F297-L299 PolarHBondContact O-N 3.4Å; F297-M300 PolarHBondContact O-N 3.27Å; F297-D301 HydrophobicContact CD2-CB 4.42Å; F297-D301 HydrophobicContact CE2-CB 4.12Å; F297-D301 VanDerWaalsContact O-CB 3.29Å; F297-D301 WeakPolarHBondContact O-CB 2.9Å; F297-D301 PolarHBondContact O-N 2.97Å; F297-I307 HydrophobicContact CD2-CG2 4.2Å; F297-I307 HydrophobicContact CE2-CG2 4.28Å; F297-M310 HydrophobicContact CB-CE 4.09Å; F297-F359 HydrophobicContact CB-CD1 3.94Å; F297-F359 HydrophobicContact CB-CE1 4.27Å; F297-F359 HydrophobicContact CG-CD1 4.1Å; F297-D362 HydrophobicContact CZ-CB 4.12Å; F297-D362 WeakPolarHBondContact CZ-OD2 3.13Å; F297-F365 AromaticContact CD2-CE2 3.65Å; F297-F365 HydrophobicContact CD2-CE2 3.65Å; F297-F365 HydrophobicContact CD2-CZ 4.14Å; F297-F365 HydrophobicContact CE2-CD2 4.45Å; F297-F365 AromaticContact CE2-CE2 3.7Å; F297-F365 HydrophobicContact CE2-CE2 3.7Å; F297-F365 HydrophobicContact CG-CE2 4.47Å
298S95.5Very high94.9Very high33 Ų3350.5 Ų50.523%0.23126%0.258CS..Hα-helixtrans-62.5-28.618074.60000113.7H294 L295 K302H294-S298 PolarHBondContact O-N 3.23Å; L295-S298 PolarHBondContact O-N 3.25Å; L295-S298 PolarHBondContact O-OG 3.4Å; S298-K302 WeakPolarHBondContact O-CE 3.45Å
299L96.5Very high95.1Very high0 Ų048.6 Ų48.60%025%0.25CC..Hα-helixtrans-79.8-47.9173.7-66.7175000111.8M231 A234 D235 L238 V270 L295 M296 F297 D301 K302M231-L299 HydrophobicContact CB-CD1 3.7Å; M231-L299 HydrophobicContact CG-CD1 3.88Å; M231-L299 HydrophobicContact SD-CD1 4.49Å; A234-L299 HydrophobicContact CB-CD1 4.39Å; A234-L299 HydrophobicContact CB-CD2 4.3Å; D235-L299 HydrophobicContact CB-CD2 4.11Å; L238-L299 HydrophobicContact CD1-CD2 3.91Å; V270-L299 HydrophobicContact CG1-CB 4.09Å; V270-L299 HydrophobicContact CG2-CD2 4.15Å; L295-L299 WeakPolarHBondContact O-CG 3.44Å; L295-L299 PolarHBondContact O-N 3.33Å; M296-L299 PolarHBondContact O-N 3.02Å; F297-L299 PolarHBondContact O-N 3.4Å; L299-D301 VanDerWaalsContact C-N 3.32Å; L299-D301 PolarHBondContact O-N 2.91Å; L299-K302 WeakPolarHBondContact O-CB 3.25Å; L299-K302 PolarHBondContact O-N 3.49Å
300M96.3Very high95.2Very high0 Ų046.5 Ų46.50%024%0.24CC..Hα-helixtrans-69.4-28-176.5-70.5-57104.400113V270 K274 I277 L278 M296 F297 K302 V303 G306 I307 M310V270-M300 HydrophobicContact CG1-CE 3.31Å; K274-M300 HydrophobicContact CG-SD 4.33Å; I277-M300 HydrophobicContact CB-CE 4.29Å; I277-M300 HydrophobicContact CD1-CE 3.95Å; I277-M300 HydrophobicContact CG2-CE 3.98Å; L278-M300 HydrophobicContact CD1-SD 4.4Å; L278-M300 HydrophobicContact CD2-CG 4.01Å; L278-M300 HydrophobicContact CD2-SD 3.93Å; L278-M300 HydrophobicContact CG-SD 4.02Å; M296-M300 HydrophobicContact CG-CG 4.18Å; M296-M300 WeakPolarHBondContact O-CB 3.1Å; M296-M300 VanDerWaalsContact O-CG 3.3Å; M296-M300 WeakPolarHBondContact O-CG 3.39Å; M296-M300 PolarHBondContact O-N 3.33Å; F297-M300 PolarHBondContact O-N 3.27Å; M300-K302 PolarHBondContact O-N 3.35Å; M300-V303 PolarHBondContact O-N 3.02Å; M300-V303 VanDerWaalsContact O-N 3.09Å; M300-V303 VanDerWaalsContact O-O 3.12Å; M300-G306 WeakPolarHBondContact O-CA 3.36Å; M300-I307 HydrophobicContact CB-CG2 4.14Å; M300-M310 HydrophobicContact CB-SD 3.77Å; M300-M310 HydrophobicContact CG-SD 3.73Å
301D95.7Very high95.3Very high77 Ų7746.8 Ų46.841%0.41224%0.241SC..THydrogen-bonded Turntrans-67.4-19.9175.7-163.153000112.5F297 L299 V303 I307 R364F297-D301 HydrophobicContact CD2-CB 4.42Å; F297-D301 HydrophobicContact CE2-CB 4.12Å; F297-D301 VanDerWaalsContact O-CB 3.29Å; F297-D301 WeakPolarHBondContact O-CB 2.9Å; F297-D301 PolarHBondContact O-N 2.97Å; L299-D301 VanDerWaalsContact C-N 3.32Å; L299-D301 PolarHBondContact O-N 2.91Å; D301-V303 VanDerWaalsContact C-N 3.33Å; D301-I307 HydrophobicContact CB-CG2 4.32Å; D301-R364 IonicContact OD1-CZ 3.52Å; D301-R364 VanDerWaalsContact OD1-CZ 3.25Å; D301-R364 IonicContact OD1-NH1 2.66Å; D301-R364 PolarHBondContact OD1-NH1 3.49Å; D301-R364 IonicContact OD1-NH2 2.96Å; D301-R364 PolarHBondContact OD1-NH2 3.23Å; D301-R364 IonicContact OD2-NH2 3.31Å
302K93.7Very high95.3Very high111 Ų11144.5 Ų44.548%0.48323%0.228SC..THydrogen-bonded Turntrans-80.5-13.5173.2-59.1178-173.3-63.20113.2L238 V266 S298 L299 M300L238-K302 HydrophobicContact CD1-CD 4.16Å; V266-K302 HydrophobicContact CG1-CB 4.09Å; V266-K302 HydrophobicContact CG2-CB 4.06Å; V266-K302 HydrophobicContact CG2-CD 4.16Å; S298-K302 WeakPolarHBondContact O-CE 3.45Å; L299-K302 WeakPolarHBondContact O-CB 3.25Å; L299-K302 PolarHBondContact O-N 3.49Å; M300-K302 PolarHBondContact O-N 3.35Å
303V93.5Very high95.4Very high10 Ų1042.7 Ų42.76%0.06122%0.221CC..SBendtrans-103.9130.1-177.2-1790000109.3V266 V270 T271 K274 M300 D301 N305 G306V266-V303 HydrophobicContact CG1-CG2 3.85Å; V270-V303 HydrophobicContact CB-CG2 3.98Å; V270-V303 HydrophobicContact CG1-CG2 3.55Å; T271-V303 HydrophobicContact CG2-CG1 4.4Å; K274-V303 HydrophobicContact CD-CG1 4.34Å; M300-V303 PolarHBondContact O-N 3.02Å; M300-V303 VanDerWaalsContact O-N 3.09Å; M300-V303 VanDerWaalsContact O-O 3.12Å; D301-V303 VanDerWaalsContact C-N 3.33Å; V303-N305 PolarHBondContact O-N 3.32Å; V303-G306 PolarHBondContact O-N 2.8Å
304P90.5Very high95.4Very high105 Ų10542.7 Ų42.768%0.68222%0.221SC*.THydrogen-bonded Turntrans-52.8125.8172.3-2634.5000111.3G306P304-G306 PolarHBondContact O-N 3.06Å; P304-G306 VanDerWaalsContact O-N 3.11Å
305N90.4Very high95.5Very high101 Ų10141.8 Ų41.854%0.5422%0.217SC..THydrogen-bonded Turntrans54.926.3-176-50.4-26.3000113.5K274 V303 I307 E308K274-N305 PolarHBondContact NZ-O 2.6Å; V303-N305 PolarHBondContact O-N 3.32Å; N305-I307 VanDerWaalsContact C-N 3.35Å; N305-E308 HydrophobicContact CB-CG 4.22Å
306G92.8Very high95.5Very high0 Ų044.4 Ų44.40%023%0.229CC..  trans-69.6-33.8177.900000112.5M300 V303 P304 P309M300-G306 WeakPolarHBondContact O-CA 3.36Å; V303-G306 PolarHBondContact O-N 2.8Å; P304-G306 PolarHBondContact O-N 3.06Å; P304-G306 VanDerWaalsContact O-N 3.11Å; G306-P309 WeakPolarHBondContact O-CD 3.31Å
307I95.4Very high95.5Very high17 Ų1745.7 Ų45.79%0.08724%0.235CC..SBendtrans-84.3-19.6-175.359.6156.8000114.6F297 M300 D301 N305 M310 L311 R364F297-I307 HydrophobicContact CD2-CG2 4.2Å; F297-I307 HydrophobicContact CE2-CG2 4.28Å; M300-I307 HydrophobicContact CB-CG2 4.14Å; D301-I307 HydrophobicContact CB-CG2 4.32Å; N305-I307 VanDerWaalsContact C-N 3.35Å; I307-M310 WeakPolarHBondContact O-CA 3.38Å; I307-M310 WeakPolarHBondContact O-CB 3.47Å; I307-M310 PolarHBondContact O-N 3Å; I307-L311 HydrophobicContact CD1-CD1 4.26Å; I307-L311 PolarHBondContact O-N 3.38Å; I307-R364 VanDerWaalsContact CD1-CD 3.45Å
308E95.7Very high95.5Very high112 Ų11244.9 Ų44.952%0.52323%0.231SC..Hα-helixtrans-57-42.1-174.6-61.2-178.4156.700112.9N305 M310 L311 K312N305-E308 HydrophobicContact CB-CG 4.22Å; E308-M310 VanDerWaalsContact C-N 3.33Å; E308-M310 PolarHBondContact O-N 2.96Å; E308-L311 PolarHBondContact O-N 3.22Å; E308-K312 PolarHBondContact O-N 3.1Å; E308-K312 VanDerWaalsContact O-N 3.09Å
309P95.8Very high95.5Very high44 Ų4446 Ų4629%0.28623%0.234SC..Hα-helixtrans-66.4-34.2175.9-24.139.7000112.5L278 G306 K312 D313L278-P309 HydrophobicContact CD1-CB 3.91Å; L278-P309 HydrophobicContact CD1-CG 3.73Å; L278-P309 HydrophobicContact CD2-CB 4.26Å; G306-P309 WeakPolarHBondContact O-CD 3.31Å; P309-K312 PolarHBondContact O-N 3.4Å; P309-D313 WeakPolarHBondContact O-CB 3.49Å; P309-D313 PolarHBondContact O-N 3.41Å
310M97.4Very high95.4Very high0 Ų049 Ų490%026%0.255CS..Hα-helixtrans-65.9-39.6175.8-56.6-179.265.600111.8L278 M296 F297 M300 I307 E308 K312 D313 L314 F359 F365L278-M310 HydrophobicContact CD2-CG 3.62Å; L278-M310 HydrophobicContact CD2-SD 4.45Å; M296-M310 HydrophobicContact CB-CE 4.1Å; M296-M310 HydrophobicContact CG-CE 3.78Å; M296-M310 HydrophobicContact CG-SD 3.98Å; M296-M310 HydrophobicContact SD-CE 3.92Å; M296-M310 HydrophobicContact SD-SD 4.32Å; F297-M310 HydrophobicContact CB-CE 4.09Å; M300-M310 HydrophobicContact CB-SD 3.77Å; M300-M310 HydrophobicContact CG-SD 3.73Å; I307-M310 WeakPolarHBondContact O-CA 3.38Å; I307-M310 WeakPolarHBondContact O-CB 3.47Å; I307-M310 PolarHBondContact O-N 3Å; E308-M310 VanDerWaalsContact C-N 3.33Å; E308-M310 PolarHBondContact O-N 2.96Å; M310-K312 VanDerWaalsContact C-N 3.34Å; M310-D313 PolarHBondContact O-N 3.43Å; M310-L314 WeakPolarHBondContact O-CB 3.41Å; M310-L314 PolarHBondContact O-N 2.99Å; M310-F359 HydrophobicContact CE-CE1 3.69Å; M310-F359 HydrophobicContact CE-CZ 4.41Å; M310-F365 HydrophobicContact CB-CE1 4.08Å; M310-F365 HydrophobicContact CB-CZ 4.02Å; M310-F365 HydrophobicContact CE-CZ 4.37Å
311L97.5Very high95.3Very high32 Ų3249.9 Ų49.917%0.16826%0.263CS..Hα-helixtrans-61-46.1174.2-65.8172.7000110.4I307 E308 L314 E315 R364 F365 A368I307-L311 HydrophobicContact CD1-CD1 4.26Å; I307-L311 PolarHBondContact O-N 3.38Å; E308-L311 PolarHBondContact O-N 3.22Å; L311-L314 PolarHBondContact O-N 2.88Å; L311-E315 WeakPolarHBondContact O-CG 3.41Å; L311-E315 PolarHBondContact O-N 2.79Å; L311-R364 HydrophobicContact CD1-CB 4.32Å; L311-R364 HydrophobicContact CD2-CB 4.06Å; L311-F365 HydrophobicContact CD2-CB 4.44Å; L311-F365 HydrophobicContact CD2-CD1 3.7Å; L311-F365 HydrophobicContact CD2-CD2 3.97Å; L311-F365 HydrophobicContact CD2-CE1 3.87Å; L311-F365 HydrophobicContact CD2-CE2 4.13Å; L311-F365 HydrophobicContact CD2-CG 3.78Å; L311-F365 HydrophobicContact CD2-CZ 4.09Å; L311-A368 HydrophobicContact CD2-CB 4.03Å
312K96.6Very high95.2Very high123 Ų12346.2 Ų46.254%0.53524%0.243SC..Hα-helixtrans-61.9-45.9177.5-174.1-177.9170.6-171.10112.1E308 P309 M310 L314 E315 E316E308-K312 PolarHBondContact O-N 3.1Å; E308-K312 VanDerWaalsContact O-N 3.09Å; P309-K312 PolarHBondContact O-N 3.4Å; M310-K312 VanDerWaalsContact C-N 3.34Å; K312-L314 VanDerWaalsContact C-N 3.32Å; K312-L314 PolarHBondContact O-N 3Å; K312-E315 PolarHBondContact O-N 2.75Å; K312-E316 WeakPolarHBondContact CE-OE1 3.35Å; K312-E316 IonicContact NZ-OE1 3.58Å; K312-E316 WeakPolarHBondContact O-CB 3.23Å; K312-E316 WeakPolarHBondContact O-CG 3.49Å; K312-E316 PolarHBondContact O-N 3.48Å
313D96.6Very high95.1Very high28 Ų2842.7 Ų42.715%0.1523%0.229CC..Hα-helixtrans-63.2-37.8178.5-76-8.6000111.9C281 Q282 I285 P309 M310 H317C281-D313 WeakPolarHBondContact CB-OD2 3.4Å; Q282-D313 PolarHBondContact N-OD2 2.79Å; I285-D313 HydrophobicContact CD1-CB 3.84Å; P309-D313 WeakPolarHBondContact O-CB 3.49Å; P309-D313 PolarHBondContact O-N 3.41Å; M310-D313 PolarHBondContact O-N 3.43Å; D313-H317 VanDerWaalsContact O-CB 3.27Å; D313-H317 WeakPolarHBondContact O-CB 3.32Å; D313-H317 PolarHBondContact O-N 3.46Å
314L97.3Very high95Very high0 Ų044.8 Ų44.80%025%0.248CC..Hα-helixtrans-65.7-46.8173.3-179.167.2000111.3I285 M310 L311 K312 E316 H317 I318 L354 V355 F359 F365I285-L314 HydrophobicContact CD1-CB 4.15Å; I285-L314 HydrophobicContact CG2-CD1 4.31Å; M310-L314 WeakPolarHBondContact O-CB 3.41Å; M310-L314 PolarHBondContact O-N 2.99Å; L311-L314 PolarHBondContact O-N 2.88Å; K312-L314 VanDerWaalsContact C-N 3.32Å; K312-L314 PolarHBondContact O-N 3Å; L314-E316 PolarHBondContact O-N 2.99Å; L314-H317 PolarHBondContact O-N 3.33Å; L314-I318 HydrophobicContact CD1-CD1 3.89Å; L314-I318 HydrophobicContact CD1-CG1 4.14Å; L314-I318 HydrophobicContact CD2-CD1 4.31Å; L314-I318 HydrophobicContact CG-CD1 3.77Å; L314-I318 HydrophobicContact CG-CG1 4.36Å; L314-I318 WeakPolarHBondContact O-CB 3.2Å; L314-I318 VanDerWaalsContact O-CG1 3.27Å; L314-I318 WeakPolarHBondContact O-CG1 3.25Å; L314-I318 PolarHBondContact O-N 3.03Å; L314-L354 HydrophobicContact CD1-CD2 3.8Å; L314-L354 HydrophobicContact CD1-CG 4.47Å; L314-V355 HydrophobicContact CD2-CG2 3.84Å; L314-F359 HydrophobicContact CD2-CE2 4.19Å; L314-F365 HydrophobicContact CD2-CB 4.36Å; L314-F365 HydrophobicContact CD2-CD1 3.73Å
315E97.2Very high95.1Very high39 Ų3941.9 Ų41.918%0.18223%0.226CC..Hα-helixtrans-57.7-49.4177.5-73.7-176-167.800111.2L311 K312 H317 I318 I319 A368 K371 A372L311-E315 WeakPolarHBondContact O-CG 3.41Å; L311-E315 PolarHBondContact O-N 2.79Å; K312-E315 PolarHBondContact O-N 2.75Å; E315-H317 PolarHBondContact O-N 3.12Å; E315-I318 PolarHBondContact O-N 3.24Å; E315-I319 VanDerWaalsContact O-CG1 3.3Å; E315-I319 WeakPolarHBondContact O-CG1 3.08Å; E315-I319 PolarHBondContact O-N 3.41Å; E315-A368 HydrophobicContact CG-CB 3.81Å; E315-K371 VanDerWaalsContact CD-NZ 3.33Å; E315-K371 WeakPolarHBondContact OE1-CD 3.37Å; E315-K371 IonicContact OE1-NZ 2.6Å; E315-K371 PolarHBondContact OE1-NZ 3.24Å; E315-K371 VanDerWaalsContact OE1-NZ 3.11Å; E315-K371 WeakPolarHBondContact OE2-CE 3.39Å; E315-K371 IonicContact OE2-NZ 2.7Å; E315-K371 PolarHBondContact OE2-NZ 2.9Å; E315-A372 HydrophobicContact CB-CB 4.25Å; E315-A372 HydrophobicContact CG-CB 4.35Å
316E96.7Very high95Very high83 Ų8337.3 Ų37.339%0.38820%0.202SC..Hα-helixtrans-62.9-40.3178.5-72.9-177.3-175.700112K312 L314 S320K312-E316 WeakPolarHBondContact CE-OE1 3.35Å; K312-E316 IonicContact NZ-OE1 3.58Å; K312-E316 WeakPolarHBondContact O-CB 3.23Å; K312-E316 WeakPolarHBondContact O-CG 3.49Å; K312-E316 PolarHBondContact O-N 3.48Å; L314-E316 PolarHBondContact O-N 2.99Å; E316-S320 VanDerWaalsContact O-CB 3.23Å; E316-S320 WeakPolarHBondContact O-CB 3.32Å; E316-S320 PolarHBondContact O-N 3.42Å; E316-S320 PolarHBondContact O-OG 3Å
317H97Very high94.7Very high26 Ų2641.4 Ų41.412%0.1223%0.227CC..Hα-helixtrans-63.7-47.7175.6176.665.9000112.1I285 D313 L314 E315 I319 S320 A321 F351I285-H317 HydrophobicContact CG2-CB 3.59Å; I285-H317 WeakPolarHBondContact CG2-CD2 3.47Å; I285-H317 VanDerWaalsContact CG2-CG 3.41Å; D313-H317 VanDerWaalsContact O-CB 3.27Å; D313-H317 WeakPolarHBondContact O-CB 3.32Å; D313-H317 PolarHBondContact O-N 3.46Å; L314-H317 PolarHBondContact O-N 3.33Å; E315-H317 PolarHBondContact O-N 3.12Å; H317-I319 VanDerWaalsContact C-N 3.32Å; H317-I319 PolarHBondContact O-N 3.35Å; H317-S320 WeakPolarHBondContact CA-OG 3.15Å; H317-S320 PolarHBondContact O-N 3.25Å; H317-S320 PolarHBondContact O-OG 3Å; H317-A321 WeakPolarHBondContact O-CB 3.46Å; H317-A321 PolarHBondContact O-N 3.43Å; H317-F351 AromaticContact CD2-CE1 3.84Å; H317-F351 AromaticContact NE2-CE1 3.76Å
318I96.7Very high94.4Very high1 Ų144.8 Ų44.81%0.00526%0.257CS..Hα-helixtrans-60.4-44.3180-70.3172.5000110.6L314 E315 G322 F351 R369 A372L314-I318 HydrophobicContact CD1-CD1 3.89Å; L314-I318 HydrophobicContact CD1-CG1 4.14Å; L314-I318 HydrophobicContact CD2-CD1 4.31Å; L314-I318 HydrophobicContact CG-CD1 3.77Å; L314-I318 HydrophobicContact CG-CG1 4.36Å; L314-I318 WeakPolarHBondContact O-CB 3.2Å; L314-I318 VanDerWaalsContact O-CG1 3.27Å; L314-I318 WeakPolarHBondContact O-CG1 3.25Å; L314-I318 PolarHBondContact O-N 3.03Å; E315-I318 PolarHBondContact O-N 3.24Å; I318-G322 WeakPolarHBondContact O-CA 3.42Å; I318-G322 PolarHBondContact O-N 2.96Å; I318-F351 HydrophobicContact CB-CD2 4.31Å; I318-F351 HydrophobicContact CB-CE1 4.49Å; I318-F351 HydrophobicContact CB-CE2 4.24Å; I318-F351 HydrophobicContact CB-CG 4.46Å; I318-F351 HydrophobicContact CB-CZ 4.31Å; I318-F351 HydrophobicContact CD1-CB 4.12Å; I318-F351 HydrophobicContact CD1-CD1 4.49Å; I318-F351 HydrophobicContact CD1-CG 4.24Å; I318-F351 HydrophobicContact CG1-CB 4.14Å; I318-F351 HydrophobicContact CG1-CD1 3.67Å; I318-F351 HydrophobicContact CG1-CD2 4.06Å; I318-F351 HydrophobicContact CG1-CE1 3.97Å; I318-F351 HydrophobicContact CG1-CE2 4.32Å; I318-F351 HydrophobicContact CG1-CG 3.71Å; I318-F351 HydrophobicContact CG1-CZ 4.27Å; I318-F351 HydrophobicContact CG2-CD2 3.74Å; I318-F351 HydrophobicContact CG2-CE2 3.81Å; I318-F351 HydrophobicContact CG2-CG 4.26Å; I318-F351 HydrophobicContact CG2-CZ 4.37Å; I318-R369 HydrophobicContact CD1-CB 3.99Å; I318-R369 HydrophobicContact CD1-CG 4.01Å; I318-A372 HydrophobicContact CB-CB 3.65Å; I318-A372 HydrophobicContact CD1-CB 4.23Å; I318-A372 HydrophobicContact CG2-CB 3.48Å; I318-A372 VanDerWaalsContact CG2-CB 3.48Å
319I95.4Very high94Very high56 Ų5640.5 Ų40.529%0.28724%0.241SC..Hα-helixtrans-65-53.8178-66.6168.4000110.3E315 H317 G322 L323 A372 A375E315-I319 VanDerWaalsContact O-CG1 3.3Å; E315-I319 WeakPolarHBondContact O-CG1 3.08Å; E315-I319 PolarHBondContact O-N 3.41Å; H317-I319 VanDerWaalsContact C-N 3.32Å; H317-I319 PolarHBondContact O-N 3.35Å; I319-G322 PolarHBondContact O-N 2.91Å; I319-L323 HydrophobicContact CG2-CD1 3.85Å; I319-L323 HydrophobicContact CG2-CG 4.43Å; I319-L323 WeakPolarHBondContact O-CB 3.42Å; I319-L323 VanDerWaalsContact O-CG 3.25Å; I319-L323 WeakPolarHBondContact O-CG 3.49Å; I319-L323 PolarHBondContact O-N 2.89Å; I319-A372 HydrophobicContact CD1-CB 4.41Å; I319-A372 HydrophobicContact CG1-CB 3.99Å; I319-A375 HydrophobicContact CD1-CB 3.9Å; I319-A375 HydrophobicContact CG1-CB 4.01Å
320S94.8Very high93.4Very high63 Ų6339.7 Ų39.744%0.44124%0.238SC..Hα-helixtrans-63.5-47.9-175.158.80000112.7E316 H317 A324E316-S320 VanDerWaalsContact O-CB 3.23Å; E316-S320 WeakPolarHBondContact O-CB 3.32Å; E316-S320 PolarHBondContact O-N 3.42Å; E316-S320 PolarHBondContact O-OG 3Å; H317-S320 WeakPolarHBondContact CA-OG 3.15Å; H317-S320 PolarHBondContact O-N 3.25Å; H317-S320 PolarHBondContact O-OG 3Å; S320-A324 VanDerWaalsContact O-CB 3.31Å; S320-A324 WeakPolarHBondContact O-CB 3.43Å; S320-A324 PolarHBondContact O-N 3.09Å
321A94.4Very high92.6Very high20 Ų2048.1 Ų48.117%0.16528%0.277CS..Hα-helixtrans-71.4-37.3178.300000111.9H317 A324 D325 F351H317-A321 WeakPolarHBondContact O-CB 3.46Å; H317-A321 PolarHBondContact O-N 3.43Å; A321-A324 PolarHBondContact O-N 2.88Å; A321-D325 WeakPolarHBondContact O-CB 3.29Å; A321-D325 VanDerWaalsContact O-CG 3.24Å; A321-D325 PolarHBondContact O-N 3.25Å; A321-F351 HydrophobicContact CB-CZ 4.08Å
322G93.3Very high92Very high0 Ų049.6 Ų49.60%029%0.287CS..Hα-helixtrans-61.5-47.4175.500000112.4I318 I319 D325 M326I318-G322 WeakPolarHBondContact O-CA 3.42Å; I318-G322 PolarHBondContact O-N 2.96Å; I319-G322 PolarHBondContact O-N 2.91Å; G322-D325 PolarHBondContact O-N 3.32Å; G322-M326 WeakPolarHBondContact O-CG 3.31Å; G322-M326 PolarHBondContact O-N 2.96Å; G322-M326 VanDerWaalsContact O-N 3.08Å
323L92.1Very high91.3Very high36 Ų3643.9 Ų43.919%0.18826%0.263CS..Hα-helixtrans-66.1-41.5176.2-67.4177.1000112.2I319 D325 M326 V327 V376 D379 I382I319-L323 HydrophobicContact CG2-CD1 3.85Å; I319-L323 HydrophobicContact CG2-CG 4.43Å; I319-L323 WeakPolarHBondContact O-CB 3.42Å; I319-L323 VanDerWaalsContact O-CG 3.25Å; I319-L323 WeakPolarHBondContact O-CG 3.49Å; I319-L323 PolarHBondContact O-N 2.89Å; L323-D325 VanDerWaalsContact C-N 3.35Å; L323-D325 PolarHBondContact O-N 3.23Å; L323-M326 PolarHBondContact O-N 3.37Å; L323-V327 WeakPolarHBondContact O-CB 3.44Å; L323-V327 VanDerWaalsContact O-CG2 3.3Å; L323-V327 WeakPolarHBondContact O-CG2 3.41Å; L323-V327 PolarHBondContact O-N 3.23Å; L323-V376 HydrophobicContact CD2-CG1 4.43Å; L323-D379 HydrophobicContact CD2-CB 3.54Å; L323-D379 VanDerWaalsContact CD2-CG 3.44Å; L323-I382 HydrophobicContact CD2-CD1 4.26Å
324A92.2Very high90.1Very high55 Ų5546 Ų4646%0.45528%0.277SS..Hα-helixtrans-59.5-44.5176.900000112.1S320 A321 V327 A328S320-A324 VanDerWaalsContact O-CB 3.31Å; S320-A324 WeakPolarHBondContact O-CB 3.43Å; S320-A324 PolarHBondContact O-N 3.09Å; A321-A324 PolarHBondContact O-N 2.88Å; A324-V327 PolarHBondContact O-N 3.23Å; A324-A328 WeakPolarHBondContact O-CB 3.43Å; A324-A328 PolarHBondContact O-N 3Å
325D91Very high89.1Confident43 Ų4351.9 Ų51.923%0.2331%0.313CS..Hα-helixtrans-65-40.5177.3-72.2-11000112.1A321 G322 L323 A328 A329 L347 R350A321-D325 WeakPolarHBondContact O-CB 3.29Å; A321-D325 VanDerWaalsContact O-CG 3.24Å; A321-D325 PolarHBondContact O-N 3.25Å; G322-D325 PolarHBondContact O-N 3.32Å; L323-D325 VanDerWaalsContact C-N 3.35Å; L323-D325 PolarHBondContact O-N 3.23Å; D325-A328 PolarHBondContact O-N 2.94Å; D325-A329 WeakPolarHBondContact O-CB 3.48Å; D325-A329 PolarHBondContact O-N 3.41Å; D325-L347 HydrophobicContact CB-CD2 3.99Å; D325-L347 WeakPolarHBondContact OD2-CD2 3.4Å; D325-R350 IonicContact OD2-CZ 3.87Å; D325-R350 IonicContact OD2-NH1 3.02Å; D325-R350 PolarHBondContact OD2-NH1 3.41Å; D325-R350 IonicContact OD2-NH2 2.86Å; D325-R350 PolarHBondContact OD2-NH2 2.84Å
326M89Confident88.6Confident5 Ų552 Ų523%0.02531%0.314CS..Hα-helixtrans-64.8-39.9176.3-65.7-8774.800111.9G322 L323 A329 A330 I333 Y340 Q343 L344 L347 V376 I382G322-M326 WeakPolarHBondContact O-CG 3.31Å; G322-M326 PolarHBondContact O-N 2.96Å; G322-M326 VanDerWaalsContact O-N 3.08Å; L323-M326 PolarHBondContact O-N 3.37Å; M326-A329 PolarHBondContact O-N 3.02Å; M326-A330 PolarHBondContact O-N 3Å; M326-I333 HydrophobicContact CE-CD1 3.87Å; M326-I333 WeakPolarHBondContact O-CD1 3.4Å; M326-Y340 HydrophobicContact SD-CE2 4.46Å; M326-Q343 HydrophobicContact CE-CB 3.55Å; M326-Q343 HydrophobicContact CE-CG 3.01Å; M326-L344 HydrophobicContact CE-CD2 4.49Å; M326-L344 HydrophobicContact SD-CD2 3.53Å; M326-L344 VanDerWaalsContact SD-CD2 3.53Å; M326-L344 HydrophobicContact SD-CG 4.07Å; M326-L347 HydrophobicContact CE-CD1 4.19Å; M326-L347 HydrophobicContact CG-CD1 3.95Å; M326-L347 HydrophobicContact SD-CD1 4.22Å; M326-V376 HydrophobicContact CG-CG1 4.31Å; M326-I382 HydrophobicContact CB-CD1 3.1Å; M326-I382 HydrophobicContact CG-CD1 4.11Å
327V87.4Confident88.1Confident87 Ų8748.9 Ų48.953%0.52730%0.302SS..Hα-helixtrans-66.8-43.8175.5170.40000110.8L323 A324 A329 A330 I382L323-V327 WeakPolarHBondContact O-CB 3.44Å; L323-V327 VanDerWaalsContact O-CG2 3.3Å; L323-V327 WeakPolarHBondContact O-CG2 3.41Å; L323-V327 PolarHBondContact O-N 3.23Å; A324-V327 PolarHBondContact O-N 3.23Å; V327-A329 PolarHBondContact O-N 3.09Å; V327-A330 WeakPolarHBondContact O-CB 3.36Å; V327-A330 PolarHBondContact O-N 3.46Å; V327-A330 VanDerWaalsContact O-N 3.13Å; V327-I382 HydrophobicContact CG2-CD1 3.75Å; V327-I382 HydrophobicContact CG2-CG1 3.85Å
328A88.5Confident87.8Confident87 Ų8749.3 Ų49.372%0.71930%0.304SS*.Hα-helixtrans-61.7-32.617800000112.5A324 D325A324-A328 WeakPolarHBondContact O-CB 3.43Å; A324-A328 PolarHBondContact O-N 3Å; D325-A328 PolarHBondContact O-N 2.94Å
329A87.2Confident87.5Confident23 Ų2353.9 Ų53.919%0.1932%0.324CS..THydrogen-bonded Turntrans-89.50.8178.300000114.2D325 M326 V327 E331 T332 I333 Q343D325-A329 WeakPolarHBondContact O-CB 3.48Å; D325-A329 PolarHBondContact O-N 3.41Å; M326-A329 PolarHBondContact O-N 3.02Å; V327-A329 PolarHBondContact O-N 3.09Å; A329-E331 PolarHBondContact O-N 3.29Å; A329-T332 PolarHBondContact O-N 3.09Å; A329-I333 HydrophobicContact CB-CD1 4.1Å; A329-I333 HydrophobicContact CB-CG2 4.02Å; A329-I333 WeakPolarHBondContact O-CG1 3.49Å; A329-I333 PolarHBondContact O-N 3.33Å; A329-Q343 HydrophobicContact CB-CG 4.47Å
330A83.8Confident87.3Confident26 Ų2651.6 Ų51.622%0.21531%0.312CS..Hα-helixtrans-54.2-43.5-169.700000113.7M326 V327 T332 I333 T334M326-A330 PolarHBondContact O-N 3Å; V327-A330 WeakPolarHBondContact O-CB 3.36Å; V327-A330 PolarHBondContact O-N 3.46Å; V327-A330 VanDerWaalsContact O-N 3.13Å; A330-T332 PolarHBondContact O-N 2.87Å; A330-T332 VanDerWaalsContact O-N 3.11Å; A330-I333 PolarHBondContact O-N 3.24Å; A330-T334 VanDerWaalsContact O-CB 3.25Å; A330-T334 WeakPolarHBondContact O-CB 3.3Å; A330-T334 WeakPolarHBondContact O-CG2 3.39Å; A330-T334 PolarHBondContact O-N 3.35Å; A330-T334 PolarHBondContact O-OG1 3.39Å
331E80.6Confident87.1Confident178 Ų17848.6 Ų48.683%0.83229%0.291SS*.Hα-helixtrans-55.9-33.5-179.4-66.2-172.7167.800113A329 T334A329-E331 PolarHBondContact O-N 3.29Å; E331-T334 PolarHBondContact O-OG1 3.49Å
332T83.3Confident87Confident62 Ų6251.3 Ų51.338%0.3830%0.3SS..Hα-helixtrans-91.2-49.2-177-65.40000111.3A329 A330 T334 T335 D336 K339A329-T332 PolarHBondContact O-N 3.09Å; A330-T332 PolarHBondContact O-N 2.87Å; A330-T332 VanDerWaalsContact O-N 3.11Å; T332-T334 VanDerWaalsContact C-N 3.26Å; T332-T334 PolarHBondContact O-N 3.49Å; T332-T335 PolarHBondContact O-N 2.95Å; T332-T335 PolarHBondContact O-OG1 3.5Å; T332-D336 PolarHBondContact O-N 2.78Å; T332-K339 HydrophobicContact CG2-CB 4.23Å; T332-K339 HydrophobicContact CG2-CD 3.12Å; T332-K339 HydrophobicContact CG2-CG 4.32Å
333I82.4Confident87Confident3 Ų353.8 Ų53.82%0.01531%0.312CS..Hα-helixtrans-75.1-15.3-172.971.2-174.9000113M326 A329 A330 T335 K339 Y340 F383M326-I333 HydrophobicContact CE-CD1 3.87Å; M326-I333 WeakPolarHBondContact O-CD1 3.4Å; A329-I333 HydrophobicContact CB-CD1 4.1Å; A329-I333 HydrophobicContact CB-CG2 4.02Å; A329-I333 WeakPolarHBondContact O-CG1 3.49Å; A329-I333 PolarHBondContact O-N 3.33Å; A330-I333 PolarHBondContact O-N 3.24Å; I333-T335 VanDerWaalsContact C-N 3.28Å; I333-T335 PolarHBondContact O-N 3.46Å; I333-K339 HydrophobicContact CG2-CB 4.19Å; I333-Y340 HydrophobicContact CB-CD2 3.98Å; I333-Y340 HydrophobicContact CB-CG 4.45Å; I333-Y340 HydrophobicContact CD1-CD2 3.87Å; I333-Y340 HydrophobicContact CD1-CE2 4.36Å; I333-Y340 HydrophobicContact CG1-CD2 3.98Å; I333-F383 HydrophobicContact CD1-CE2 3.87Å; I333-F383 HydrophobicContact CD1-CZ 4.37Å; I333-F383 HydrophobicContact CG1-CE2 3.78Å; I333-F383 HydrophobicContact CG1-CZ 3.77Å
334T72.8Confident87.1Confident72 Ų7252 Ų5244%0.44230%0.303SS..THydrogen-bonded Turntrans-67.9-26.4174.348.30000113.5A330 E331 T332 F383A330-T334 VanDerWaalsContact O-CB 3.25Å; A330-T334 WeakPolarHBondContact O-CB 3.3Å; A330-T334 WeakPolarHBondContact O-CG2 3.39Å; A330-T334 PolarHBondContact O-N 3.35Å; A330-T334 PolarHBondContact O-OG1 3.39Å; E331-T334 PolarHBondContact O-OG1 3.49Å; T332-T334 VanDerWaalsContact C-N 3.26Å; T332-T334 PolarHBondContact O-N 3.49Å; T334-F383 HydrophobicContact CG2-CD1 4.49Å; T334-F383 HydrophobicContact CG2-CE1 3.3Å; T334-F383 HydrophobicContact CG2-CZ 3.41Å; T334-F383 VanDerWaalsContact CG2-CZ 3.41Å
335T76.3Confident87.2Confident124 Ų12450 Ų5076%0.76128%0.284SS*.THydrogen-bonded Turntrans-109.9-12.8-175.660.70000113T332 I333T332-T335 PolarHBondContact O-N 2.95Å; T332-T335 PolarHBondContact O-OG1 3.5Å; I333-T335 VanDerWaalsContact C-N 3.28Å; I333-T335 PolarHBondContact O-N 3.46Å
336D85.4Confident87.4Confident41 Ų4151.7 Ų51.722%0.21930%0.296CS..  trans-131.4105.1-171.9-166.3-20.4000111.2T332 E338 K339 Y340T332-D336 PolarHBondContact O-N 2.78Å; D336-E338 VanDerWaalsContact C-N 3.26Å; D336-E338 PolarHBondContact O-N 3.17Å; D336-E338 WeakPolarHBondContact OD1-CB 3.5Å; D336-E338 PolarHBondContact OD1-N 2.94Å; D336-K339 HydrophobicContact CB-CB 4.22Å; D336-K339 HydrophobicContact CB-CD 4.17Å; D336-K339 HydrophobicContact CB-CG 4.24Å; D336-K339 PolarHBondContact O-N 3.13Å; D336-K339 WeakPolarHBondContact OD2-CD 3.32Å; D336-K339 WeakPolarHBondContact OD2-CE 3.4Å; D336-K339 WeakPolarHBondContact OD2-CG 3.24Å; D336-Y340 PolarHBondContact O-N 3.24Å; D336-Y340 VanDerWaalsContact O-N 3.13Å
337S86.9Confident87.7Confident18 Ų1851.5 Ų51.513%0.12630%0.295CS..Hα-helixtrans-65-28.3179.3-55.20000112.8V341S337-V341 WeakPolarHBondContact O-CG2 3.41Å; S337-V341 PolarHBondContact O-N 3.21Å
338E89.6Confident88.1Confident35 Ų3548.3 Ų48.316%0.16427%0.274CS..Hα-helixtrans-65.1-54.4176.9172.8161.6-138.200110.2D336 Y340 V341 E342 Y411D336-E338 VanDerWaalsContact C-N 3.26Å; D336-E338 PolarHBondContact O-N 3.17Å; D336-E338 WeakPolarHBondContact OD1-CB 3.5Å; D336-E338 PolarHBondContact OD1-N 2.94Å; E338-Y340 VanDerWaalsContact C-N 3.26Å; E338-Y340 PolarHBondContact O-N 3.36Å; E338-V341 PolarHBondContact O-N 3.4Å; E338-V341 VanDerWaalsContact O-N 3.1Å; E338-E342 HydrophobicContact CG-CG 4.48Å; E338-E342 WeakPolarHBondContact O-CG 2.96Å; E338-E342 PolarHBondContact O-N 3.04Å; E338-Y411 HydrophobicContact CB-CD2 3.73Å; E338-Y411 HydrophobicContact CB-CE2 3.4Å; E338-Y411 HydrophobicContact CG-CD2 4.31Å; E338-Y411 HydrophobicContact CG-CE2 3.48Å; E338-Y411 VanDerWaalsContact CG-CE2 3.48Å; E338-Y411 PolarHBondContact OE1-OH 3.47Å
339K90.9Very high88.5Confident97 Ų9748.7 Ų48.742%0.42226%0.264SS..Hα-helixtrans-63.8-32.6-179.1-64.2-177.6-176.5178.70112.9T332 I333 D336 Q343T332-K339 HydrophobicContact CG2-CB 4.23Å; T332-K339 HydrophobicContact CG2-CD 3.12Å; T332-K339 HydrophobicContact CG2-CG 4.32Å; I333-K339 HydrophobicContact CG2-CB 4.19Å; D336-K339 HydrophobicContact CB-CB 4.22Å; D336-K339 HydrophobicContact CB-CD 4.17Å; D336-K339 HydrophobicContact CB-CG 4.24Å; D336-K339 PolarHBondContact O-N 3.13Å; D336-K339 WeakPolarHBondContact OD2-CD 3.32Å; D336-K339 WeakPolarHBondContact OD2-CE 3.4Å; D336-K339 WeakPolarHBondContact OD2-CG 3.24Å; K339-Q343 WeakPolarHBondContact O-CB 3.14Å; K339-Q343 PolarHBondContact O-N 3.39Å
340Y90.4Very high88.9Confident8 Ų852.3 Ų52.33%0.03127%0.273CS..Hα-helixtrans-59.1-49172.9-179.4-97.1000111.9M326 I333 D336 E338 Q343 L344 F383 C404 L407M326-Y340 HydrophobicContact SD-CE2 4.46Å; I333-Y340 HydrophobicContact CB-CD2 3.98Å; I333-Y340 HydrophobicContact CB-CG 4.45Å; I333-Y340 HydrophobicContact CD1-CD2 3.87Å; I333-Y340 HydrophobicContact CD1-CE2 4.36Å; I333-Y340 HydrophobicContact CG1-CD2 3.98Å; D336-Y340 PolarHBondContact O-N 3.24Å; D336-Y340 VanDerWaalsContact O-N 3.13Å; E338-Y340 VanDerWaalsContact C-N 3.26Å; E338-Y340 PolarHBondContact O-N 3.36Å; Y340-Q343 PolarHBondContact O-N 2.93Å; Y340-L344 HydrophobicContact CD1-CD1 4.13Å; Y340-L344 HydrophobicContact CE1-CD1 3.49Å; Y340-L344 VanDerWaalsContact CE1-CD1 3.49Å; Y340-L344 HydrophobicContact CE1-CG 4.39Å; Y340-L344 PolarHBondContact O-N 3.48Å; Y340-F383 HydrophobicContact CD2-CD2 4.16Å; Y340-F383 AromaticContact CD2-CE2 3.7Å; Y340-F383 HydrophobicContact CD2-CE2 3.7Å; Y340-F383 HydrophobicContact CD2-CZ 4.35Å; Y340-F383 AromaticContact CE2-CD2 3.51Å; Y340-F383 HydrophobicContact CE2-CD2 3.51Å; Y340-F383 AromaticContact CE2-CE2 3.49Å; Y340-F383 HydrophobicContact CE2-CE2 3.49Å; Y340-F383 VanDerWaalsContact CE2-CE2 3.49Å; Y340-F383 HydrophobicContact CE2-CZ 4.49Å; Y340-C404 HydrophobicContact CE1-CB 4.22Å; Y340-C404 WeakPolarHBondContact OH-CB 3.4Å; Y340-L407 HydrophobicContact CD1-CB 3.79Å; Y340-L407 HydrophobicContact CD1-CD1 3.58Å; Y340-L407 HydrophobicContact CD1-CG 4.32Å; Y340-L407 HydrophobicContact CD2-CD1 3.78Å; Y340-L407 HydrophobicContact CE1-CB 4.06Å; Y340-L407 HydrophobicContact CE1-CD1 3.64Å; Y340-L407 HydrophobicContact CE1-CG 4.5Å; Y340-L407 HydrophobicContact CE2-CD1 3.88Å; Y340-L407 HydrophobicContact CG-CB 4.47Å; Y340-L407 HydrophobicContact CG-CD1 3.65Å
341V91.7Very high89.5Confident0 Ų051.3 Ų51.30%026%0.263CS..Hα-helixtrans-69.7-41.8-179.3178.10000111.2S337 E338 Q343 L344 L345 L408 Y411 V437S337-V341 WeakPolarHBondContact O-CG2 3.41Å; S337-V341 PolarHBondContact O-N 3.21Å; E338-V341 PolarHBondContact O-N 3.4Å; E338-V341 VanDerWaalsContact O-N 3.1Å; V341-Q343 VanDerWaalsContact C-N 3.27Å; V341-Q343 PolarHBondContact O-N 3.01Å; V341-L344 PolarHBondContact O-N 2.94Å; V341-L344 VanDerWaalsContact O-N 3.15Å; V341-L345 HydrophobicContact CG1-CD1 3.91Å; V341-L345 HydrophobicContact CG1-CG 4.32Å; V341-L345 WeakPolarHBondContact O-CG 3.35Å; V341-L345 PolarHBondContact O-N 2.98Å; V341-L408 HydrophobicContact CG1-CD2 4.22Å; V341-L408 HydrophobicContact CG2-CD2 3.65Å; V341-Y411 HydrophobicContact CB-CD1 3.93Å; V341-Y411 HydrophobicContact CB-CE1 4.32Å; V341-Y411 HydrophobicContact CG1-CD1 4.01Å; V341-Y411 HydrophobicContact CG1-CE1 4.24Å; V341-Y411 HydrophobicContact CG2-CD1 3.97Å; V341-Y411 HydrophobicContact CG2-CG 4.33Å; V341-V437 HydrophobicContact CG1-CG2 4.24Å
342E92.6Very high90.3Very high77 Ų7743.8 Ų43.836%0.3623%0.231SC..Hα-helixtrans-58.8-38.5176.1-72.3-177.1161.800112.4E338 L345 T346 K433E338-E342 HydrophobicContact CG-CG 4.48Å; E338-E342 WeakPolarHBondContact O-CG 2.96Å; E338-E342 PolarHBondContact O-N 3.04Å; E342-L345 PolarHBondContact O-N 3.48Å; E342-T346 WeakPolarHBondContact O-CB 3.47Å; E342-T346 PolarHBondContact O-N 3.43Å; E342-T346 PolarHBondContact O-OG1 3.41Å; E342-K433 IonicContact OE1-NZ 3.6Å
343Q93.1Very high90.9Very high52 Ų5246.6 Ų46.624%0.24324%0.237CC..Hα-helixtrans-68.3-40.7176.5-172.66726.700111.7M326 A329 K339 Y340 V341 L345 T346 L347M326-Q343 HydrophobicContact CE-CB 3.55Å; M326-Q343 HydrophobicContact CE-CG 3.01Å; A329-Q343 HydrophobicContact CB-CG 4.47Å; K339-Q343 WeakPolarHBondContact O-CB 3.14Å; K339-Q343 PolarHBondContact O-N 3.39Å; Y340-Q343 PolarHBondContact O-N 2.93Å; V341-Q343 VanDerWaalsContact C-N 3.27Å; V341-Q343 PolarHBondContact O-N 3.01Å; Q343-L345 VanDerWaalsContact C-N 3.34Å; Q343-L345 PolarHBondContact O-N 2.92Å; Q343-T346 PolarHBondContact O-N 3.4Å; Q343-L347 WeakPolarHBondContact O-CG 3.45Å; Q343-L347 PolarHBondContact O-N 2.79Å
344L93.8Very high91.6Very high0 Ų046.6 Ų46.60%024%0.238CC..Hα-helixtrans-63-38.4173.7-75.9177.6000112.5M326 Y340 V341 L347 F348 Y373 V377 V440M326-L344 HydrophobicContact CE-CD2 4.49Å; M326-L344 HydrophobicContact SD-CD2 3.53Å; M326-L344 VanDerWaalsContact SD-CD2 3.53Å; M326-L344 HydrophobicContact SD-CG 4.07Å; Y340-L344 HydrophobicContact CD1-CD1 4.13Å; Y340-L344 HydrophobicContact CE1-CD1 3.49Å; Y340-L344 VanDerWaalsContact CE1-CD1 3.49Å; Y340-L344 HydrophobicContact CE1-CG 4.39Å; Y340-L344 PolarHBondContact O-N 3.48Å; V341-L344 PolarHBondContact O-N 2.94Å; V341-L344 VanDerWaalsContact O-N 3.15Å; L344-L347 HydrophobicContact CD2-CD1 4.49Å; L344-L347 PolarHBondContact O-N 2.97Å; L344-F348 PolarHBondContact O-N 3.48Å; L344-Y373 WeakPolarHBondContact O-CE2 3.28Å; L344-Y373 PolarHBondContact O-OH 2.79Å; L344-V377 HydrophobicContact CD2-CG2 4.23Å; L344-V440 HydrophobicContact CD1-CG1 3.96Å
345L94.8Very high92.8Very high13 Ų1343.2 Ų43.27%0.06822%0.217CC..Hα-helixtrans-67.9-40.9175.5-70.5167.5000111.6V341 E342 Q343 L347 F348 N349 E436 V440V341-L345 HydrophobicContact CG1-CD1 3.91Å; V341-L345 HydrophobicContact CG1-CG 4.32Å; V341-L345 WeakPolarHBondContact O-CG 3.35Å; V341-L345 PolarHBondContact O-N 2.98Å; E342-L345 PolarHBondContact O-N 3.48Å; Q343-L345 VanDerWaalsContact C-N 3.34Å; Q343-L345 PolarHBondContact O-N 2.92Å; L345-L347 VanDerWaalsContact C-N 3.32Å; L345-L347 PolarHBondContact O-N 3.32Å; L345-F348 WeakPolarHBondContact O-CB 3.3Å; L345-F348 PolarHBondContact O-N 3.32Å; L345-N349 WeakPolarHBondContact O-CB 3.39Å; L345-N349 PolarHBondContact O-N 2.69Å; L345-N349 PolarHBondContact O-ND2 3.02Å; L345-E436 HydrophobicContact CD1-CB 3.72Å; L345-E436 HydrophobicContact CD1-CG 4.45Å; L345-E436 HydrophobicContact CD2-CB 3.85Å; L345-E436 HydrophobicContact CG-CB 4.45Å; L345-V440 HydrophobicContact CD2-CG2 3.67Å; L345-V440 HydrophobicContact CG-CG2 4.11Å
346T95.5Very high93.8Very high78 Ų7843.6 Ų43.648%0.47921%0.208SC..Hα-helixtrans-59.2-44.3175-61.80000111.1E342 Q343 N349 R350E342-T346 WeakPolarHBondContact O-CB 3.47Å; E342-T346 PolarHBondContact O-N 3.43Å; E342-T346 PolarHBondContact O-OG1 3.41Å; Q343-T346 PolarHBondContact O-N 3.4Å; T346-N349 PolarHBondContact O-N 3.19Å; T346-R350 WeakPolarHBondContact O-CB 3.36Å; T346-R350 PolarHBondContact O-N 2.93Å
347L94.8Very high94.3Very high1 Ų145.8 Ų45.81%0.00522%0.217CC..Hα-helixtrans-60-47.8173.9-71.3174.9000111.8D325 M326 Q343 L344 L345 N349 R350 F351 Y373 V376D325-L347 HydrophobicContact CB-CD2 3.99Å; D325-L347 WeakPolarHBondContact OD2-CD2 3.4Å; M326-L347 HydrophobicContact CE-CD1 4.19Å; M326-L347 HydrophobicContact CG-CD1 3.95Å; M326-L347 HydrophobicContact SD-CD1 4.22Å; Q343-L347 WeakPolarHBondContact O-CG 3.45Å; Q343-L347 PolarHBondContact O-N 2.79Å; L344-L347 HydrophobicContact CD2-CD1 4.49Å; L344-L347 PolarHBondContact O-N 2.97Å; L345-L347 VanDerWaalsContact C-N 3.32Å; L345-L347 PolarHBondContact O-N 3.32Å; L347-N349 PolarHBondContact O-N 3.48Å; L347-R350 PolarHBondContact O-N 3Å; L347-F351 HydrophobicContact CB-CE2 4.41Å; L347-F351 HydrophobicContact CD2-CE2 4.08Å; L347-F351 WeakPolarHBondContact O-CD2 3.39Å; L347-F351 PolarHBondContact O-N 2.81Å; L347-F351 VanDerWaalsContact O-N 3.07Å; L347-Y373 HydrophobicContact CB-CE2 4.33Å; L347-V376 HydrophobicContact CD1-CG1 4.4Å
348F96.1Very high94.8Very high20 Ų2044.9 Ų44.99%0.08821%0.211CC..Hα-helixtrans-58.8-47.5178.9-175.7-96.3000112L344 L345 S352 Y373 L439 Y443L344-F348 PolarHBondContact O-N 3.48Å; L345-F348 WeakPolarHBondContact O-CB 3.3Å; L345-F348 PolarHBondContact O-N 3.32Å; F348-S352 VanDerWaalsContact O-CB 3.24Å; F348-S352 WeakPolarHBondContact O-CB 3.24Å; F348-S352 PolarHBondContact O-N 3.45Å; F348-S352 PolarHBondContact O-OG 2.84Å; F348-Y373 HydrophobicContact CB-CD2 4.3Å; F348-Y373 HydrophobicContact CB-CE1 4.44Å; F348-Y373 HydrophobicContact CB-CE2 3.64Å; F348-Y373 AromaticContact CD2-CD1 3.89Å; F348-Y373 HydrophobicContact CD2-CD1 3.89Å; F348-Y373 HydrophobicContact CD2-CD2 4.16Å; F348-Y373 AromaticContact CD2-CE1 3.85Å; F348-Y373 HydrophobicContact CD2-CE1 3.85Å; F348-Y373 HydrophobicContact CD2-CE2 4.13Å; F348-Y373 HydrophobicContact CD2-CG 4.05Å; F348-Y373 AromaticContact CD2-CZ 3.97Å; F348-Y373 HydrophobicContact CG-CE2 4.4Å; F348-L439 HydrophobicContact CD1-CD2 3.86Å; F348-L439 HydrophobicContact CE1-CD2 3.73Å; F348-L439 HydrophobicContact CZ-CD1 4.32Å; F348-L439 HydrophobicContact CZ-CD2 4.31Å; F348-Y443 HydrophobicContact CD2-CE2 4.38Å; F348-Y443 AromaticContact CE2-CE2 3.94Å; F348-Y443 HydrophobicContact CE2-CE2 3.94Å; F348-Y443 AromaticContact CE2-CZ 3.87Å; F348-Y443 WeakPolarHBondContact CE2-OH 3.33Å
349N96.2Very high95.1Very high95 Ų9543.2 Ų43.251%0.50820%0.203SC..Hα-helixtrans-65.6-42.5-179.4-72.2-26.7000111.7L345 T346 L347 S352 K353L345-N349 WeakPolarHBondContact O-CB 3.39Å; L345-N349 PolarHBondContact O-N 2.69Å; L345-N349 PolarHBondContact O-ND2 3.02Å; T346-N349 PolarHBondContact O-N 3.19Å; L347-N349 PolarHBondContact O-N 3.48Å; N349-S352 PolarHBondContact O-N 3.02Å; N349-K353 WeakPolarHBondContact O-CB 3.44Å; N349-K353 PolarHBondContact O-N 3.08Å
350R96Very high95.3Very high99 Ų9945 Ų4537%0.37421%0.213SC..Hα-helixtrans-58.8-50.8177-177.6178.470.9-167.4-1.6111.7D325 T346 L347 K353 L354D325-R350 IonicContact OD2-CZ 3.87Å; D325-R350 IonicContact OD2-NH1 3.02Å; D325-R350 PolarHBondContact OD2-NH1 3.41Å; D325-R350 IonicContact OD2-NH2 2.86Å; D325-R350 PolarHBondContact OD2-NH2 2.84Å; T346-R350 WeakPolarHBondContact O-CB 3.36Å; T346-R350 PolarHBondContact O-N 2.93Å; L347-R350 PolarHBondContact O-N 3Å; R350-K353 PolarHBondContact O-N 2.98Å; R350-L354 PolarHBondContact O-N 3.42Å; R350-L354 VanDerWaalsContact O-N 3.08Å
351F96.7Very high95.6Very high4 Ų447.9 Ų47.92%0.01823%0.228CC..Hα-helixtrans-74.9-29.7-177.5-62.8-52.4000112.9H317 I318 A321 L347 L354 V355 R369H317-F351 AromaticContact CD2-CE1 3.84Å; H317-F351 AromaticContact NE2-CE1 3.76Å; I318-F351 HydrophobicContact CB-CD2 4.31Å; I318-F351 HydrophobicContact CB-CE1 4.49Å; I318-F351 HydrophobicContact CB-CE2 4.24Å; I318-F351 HydrophobicContact CB-CG 4.46Å; I318-F351 HydrophobicContact CB-CZ 4.31Å; I318-F351 HydrophobicContact CD1-CB 4.12Å; I318-F351 HydrophobicContact CD1-CD1 4.49Å; I318-F351 HydrophobicContact CD1-CG 4.24Å; I318-F351 HydrophobicContact CG1-CB 4.14Å; I318-F351 HydrophobicContact CG1-CD1 3.67Å; I318-F351 HydrophobicContact CG1-CD2 4.06Å; I318-F351 HydrophobicContact CG1-CE1 3.97Å; I318-F351 HydrophobicContact CG1-CE2 4.32Å; I318-F351 HydrophobicContact CG1-CG 3.71Å; I318-F351 HydrophobicContact CG1-CZ 4.27Å; I318-F351 HydrophobicContact CG2-CD2 3.74Å; I318-F351 HydrophobicContact CG2-CE2 3.81Å; I318-F351 HydrophobicContact CG2-CG 4.26Å; I318-F351 HydrophobicContact CG2-CZ 4.37Å; A321-F351 HydrophobicContact CB-CZ 4.08Å; L347-F351 HydrophobicContact CB-CE2 4.41Å; L347-F351 HydrophobicContact CD2-CE2 4.08Å; L347-F351 WeakPolarHBondContact O-CD2 3.39Å; L347-F351 PolarHBondContact O-N 2.81Å; L347-F351 VanDerWaalsContact O-N 3.07Å; F351-L354 HydrophobicContact CD1-CD2 4.46Å; F351-L354 PolarHBondContact O-N 3.1Å; F351-V355 WeakPolarHBondContact O-CG2 3.19Å; F351-V355 PolarHBondContact O-N 2.68Å; F351-R369 HydrophobicContact CB-CG 4.3Å
352S96.5Very high95.9Very high20 Ų2049 Ų4914%0.1424%0.235CC..Hα-helixtrans-65.3-40.2170.7-63.30000111.8F348 N349 V355 K356 R369F348-S352 VanDerWaalsContact O-CB 3.24Å; F348-S352 WeakPolarHBondContact O-CB 3.24Å; F348-S352 PolarHBondContact O-N 3.45Å; F348-S352 PolarHBondContact O-OG 2.84Å; N349-S352 PolarHBondContact O-N 3.02Å; S352-V355 PolarHBondContact O-N 3.04Å; S352-K356 WeakPolarHBondContact O-CB 3.47Å; S352-K356 PolarHBondContact O-N 3.04Å; S352-R369 WeakPolarHBondContact OG-CD 3.32Å; S352-R369 PolarHBondContact OG-NH1 2.91Å
353K96.8Very high96.1Very high121 Ų12149.7 Ų49.753%0.52625%0.246SC..Hα-helixtrans-61.9-45173.6-176.1179.6177.8-177.30111.8N349 R350 V355 K356 E357N349-K353 WeakPolarHBondContact O-CB 3.44Å; N349-K353 PolarHBondContact O-N 3.08Å; R350-K353 PolarHBondContact O-N 2.98Å; K353-V355 PolarHBondContact O-N 3.38Å; K353-K356 PolarHBondContact O-N 3.01Å; K353-E357 VanDerWaalsContact CE-CD 3.47Å; K353-E357 WeakPolarHBondContact CE-OE1 3.25Å; K353-E357 HydrophobicContact CG-CG 4.33Å; K353-E357 IonicContact NZ-OE1 3.64Å; K353-E357 WeakPolarHBondContact O-CB 3.45Å; K353-E357 WeakPolarHBondContact O-CG 3.47Å; K353-E357 PolarHBondContact O-N 3.45Å
354L96.8Very high96.3Very high4 Ų451.5 Ų51.52%0.02125%0.25CS..Hα-helixtrans-56.4-48.2175171.159.9000111.5I285 T290 L293 L314 R350 F351 K356 E357 A358I285-L354 HydrophobicContact CG2-CD2 4.23Å; T290-L354 HydrophobicContact CG2-CD1 4.09Å; L293-L354 HydrophobicContact CD1-CD1 4.12Å; L314-L354 HydrophobicContact CD1-CD2 3.8Å; L314-L354 HydrophobicContact CD1-CG 4.47Å; R350-L354 PolarHBondContact O-N 3.42Å; R350-L354 VanDerWaalsContact O-N 3.08Å; F351-L354 HydrophobicContact CD1-CD2 4.46Å; F351-L354 PolarHBondContact O-N 3.1Å; L354-K356 PolarHBondContact O-N 3.46Å; L354-E357 PolarHBondContact O-N 3.32Å; L354-A358 HydrophobicContact CD1-CB 4.16Å; L354-A358 WeakPolarHBondContact O-CB 3.46Å; L354-A358 PolarHBondContact O-N 2.71Å
355V97.5Very high96.5Very high0 Ų051.5 Ų51.50%025%0.25CS..Hα-helixtrans-63.1-43.1179.3172.70000111.9L314 F351 S352 K353 F359 Q360 F365 L366 R369L314-V355 HydrophobicContact CD2-CG2 3.84Å; F351-V355 WeakPolarHBondContact O-CG2 3.19Å; F351-V355 PolarHBondContact O-N 2.68Å; S352-V355 PolarHBondContact O-N 3.04Å; K353-V355 PolarHBondContact O-N 3.38Å; V355-F359 CarbonylContact O-C 3.15Å; V355-F359 WeakPolarHBondContact O-CA 3.44Å; V355-F359 WeakPolarHBondContact O-CB 3.44Å; V355-F359 PolarHBondContact O-N 3.3Å; V355-Q360 PolarHBondContact O-N 2.94Å; V355-F365 HydrophobicContact CG1-CB 3.93Å; V355-L366 HydrophobicContact CG1-CD2 3.81Å; V355-L366 HydrophobicContact CG1-CG 4.17Å; V355-R369 HydrophobicContact CG2-CB 4.1Å
356K97.4Very high96.6Very high133 Ų13353 Ų5358%0.57826%0.258SS*.Hα-helixtrans-60.2-48.9177-178.5173.5-175.8179.40112.4S352 K353 L354 Q360 D361S352-K356 WeakPolarHBondContact O-CB 3.47Å; S352-K356 PolarHBondContact O-N 3.04Å; K353-K356 PolarHBondContact O-N 3.01Å; L354-K356 PolarHBondContact O-N 3.46Å; K356-Q360 VanDerWaalsContact O-CA 3.29Å; K356-Q360 WeakPolarHBondContact O-CA 3.41Å; K356-Q360 PolarHBondContact O-N 3.31Å; K356-Q360 VanDerWaalsContact O-N 3.15Å; K356-D361 WeakPolarHBondContact CA-OD1 3.46Å; K356-D361 WeakPolarHBondContact CB-OD1 3.36Å
357E96.8Very high96.7Very high86 Ų8653.7 Ų53.740%0.40226%0.262SS..Hα-helixtrans-77.3-39.2-173.9-69.9179.1174.900112.9T290 K353 L354T290-E357 HydrophobicContact CG2-CB 3.73Å; K353-E357 VanDerWaalsContact CE-CD 3.47Å; K353-E357 WeakPolarHBondContact CE-OE1 3.25Å; K353-E357 HydrophobicContact CG-CG 4.33Å; K353-E357 IonicContact NZ-OE1 3.64Å; K353-E357 WeakPolarHBondContact O-CB 3.45Å; K353-E357 WeakPolarHBondContact O-CG 3.47Å; K353-E357 PolarHBondContact O-N 3.45Å; L354-E357 PolarHBondContact O-N 3.32Å
358A96.3Very high96.8Very high0 Ų053.7 Ų53.70%026%0.263CS..Hα-helixtrans-85-37.2-178.400000113.2T290 L293 H294 L354T290-A358 HydrophobicContact CG2-CB 4.29Å; L293-A358 HydrophobicContact CB-CB 3.71Å; L293-A358 HydrophobicContact CD1-CB 3.94Å; L293-A358 HydrophobicContact CG-CB 4.5Å; H294-A358 WeakPolarHBondContact CA-O 3.47Å; H294-A358 WeakPolarHBondContact CB-O 3.28Å; H294-A358 PolarHBondContact N-O 3.11Å; H294-A358 PolarHBondContact ND1-O 3.33Å; L354-A358 HydrophobicContact CD1-CB 4.16Å; L354-A358 WeakPolarHBondContact O-CB 3.46Å; L354-A358 PolarHBondContact O-N 2.71Å
359F96.8Very high96.9Very high0 Ų054 Ų540%026%0.263CS..Hα-helixtrans-123.210-168.1-49.8-61.2000113.3L293 F297 M310 L314 V355 D361 D362 F365L293-F359 HydrophobicContact CB-CE1 4.18Å; L293-F359 HydrophobicContact CB-CZ 4.27Å; L293-F359 HydrophobicContact CD1-CZ 4.44Å; L293-F359 HydrophobicContact CD2-CZ 4.42Å; F297-F359 HydrophobicContact CB-CD1 3.94Å; F297-F359 HydrophobicContact CB-CE1 4.27Å; F297-F359 HydrophobicContact CG-CD1 4.1Å; M310-F359 HydrophobicContact CE-CE1 3.69Å; M310-F359 HydrophobicContact CE-CZ 4.41Å; L314-F359 HydrophobicContact CD2-CE2 4.19Å; V355-F359 CarbonylContact O-C 3.15Å; V355-F359 WeakPolarHBondContact O-CA 3.44Å; V355-F359 WeakPolarHBondContact O-CB 3.44Å; V355-F359 PolarHBondContact O-N 3.3Å; F359-D361 VanDerWaalsContact C-N 3.26Å; F359-D361 PolarHBondContact O-N 3.49Å; F359-D362 HydrophobicContact CB-CB 4.49Å; F359-D362 VanDerWaalsContact O-CB 3.25Å; F359-D362 WeakPolarHBondContact O-CB 3.33Å; F359-D362 PolarHBondContact O-N 3.38Å; F359-F365 HydrophobicContact CB-CB 4.05Å; F359-F365 HydrophobicContact CB-CD1 4.32Å; F359-F365 HydrophobicContact CB-CD2 3.81Å; F359-F365 HydrophobicContact CB-CE2 4.31Å; F359-F365 HydrophobicContact CB-CG 3.79Å; F359-F365 AromaticContact CD1-CD1 3.98Å; F359-F365 HydrophobicContact CD1-CD1 3.98Å; F359-F365 HydrophobicContact CD1-CD2 4.16Å; F359-F365 AromaticContact CD1-CE1 3.69Å; F359-F365 HydrophobicContact CD1-CE1 3.69Å; F359-F365 AromaticContact CD1-CE2 3.88Å; F359-F365 HydrophobicContact CD1-CE2 3.88Å; F359-F365 HydrophobicContact CD1-CG 4.19Å; F359-F365 AromaticContact CD1-CZ 3.62Å; F359-F365 HydrophobicContact CD1-CZ 3.62Å; F359-F365 HydrophobicContact CD2-CB 4.03Å; F359-F365 AromaticContact CD2-CD1 3.37Å; F359-F365 HydrophobicContact CD2-CD1 3.37Å; F359-F365 HydrophobicContact CD2-CD2 4.4Å; F359-F365 AromaticContact CD2-CE1 3.84Å; F359-F365 HydrophobicContact CD2-CE1 3.84Å; F359-F365 AromaticContact CD2-CG 3.68Å; F359-F365 HydrophobicContact CD2-CG 3.68Å; F359-F365 HydrophobicContact CE1-CD1 4.14Å; F359-F365 AromaticContact CE1-CE1 3.57Å; F359-F365 HydrophobicContact CE1-CE1 3.57Å; F359-F365 HydrophobicContact CE1-CE2 4.45Å; F359-F365 AromaticContact CE1-CZ 3.74Å; F359-F365 HydrophobicContact CE1-CZ 3.74Å; F359-F365 AromaticContact CE2-CD1 3.56Å; F359-F365 HydrophobicContact CE2-CD1 3.56Å; F359-F365 AromaticContact CE2-CE1 3.73Å; F359-F365 HydrophobicContact CE2-CE1 3.73Å; F359-F365 HydrophobicContact CE2-CG 4.34Å; F359-F365 HydrophobicContact CG-CB 4.19Å; F359-F365 AromaticContact CG-CD1 3.61Å; F359-F365 HydrophobicContact CG-CD1 3.61Å; F359-F365 AromaticContact CG-CD2 3.86Å; F359-F365 HydrophobicContact CG-CD2 3.86Å; F359-F365 AromaticContact CG-CE1 3.84Å; F359-F365 HydrophobicContact CG-CE1 3.84Å; F359-F365 HydrophobicContact CG-CE2 4.07Å; F359-F365 AromaticContact CG-CG 3.61Å; F359-F365 HydrophobicContact CG-CG 3.61Å; F359-F365 HydrophobicContact CG-CZ 4.06Å; F359-F365 AromaticContact CZ-CD1 3.95Å; F359-F365 HydrophobicContact CZ-CD1 3.95Å; F359-F365 AromaticContact CZ-CE1 3.58Å; F359-F365 HydrophobicContact CZ-CE1 3.58Å; F359-F365 HydrophobicContact CZ-CZ 4.24Å
360Q95.7Very high96.9Very high134 Ų13451.8 Ų51.863%0.62625%0.251SS*.THydrogen-bonded Turntrans53.538.8176.4-62.9-176.2-19.900114H294 V355 K356 D362H294-Q360 PolarHBondContact CE1-NE2 3.45Å; H294-Q360 PolarHBondContact NE2-NE2 3.17Å; V355-Q360 PolarHBondContact O-N 2.94Å; K356-Q360 VanDerWaalsContact O-CA 3.29Å; K356-Q360 WeakPolarHBondContact O-CA 3.41Å; K356-Q360 PolarHBondContact O-N 3.31Å; K356-Q360 VanDerWaalsContact O-N 3.15Å; Q360-D362 PolarHBondContact O-N 3.39Å
361D96.4Very high96.9Very high68 Ų6853.1 Ų53.136%0.36426%0.26SS..THydrogen-bonded Turntrans56.731.7-176.8-67.4-41.2000113.3K356 F359 L366K356-D361 WeakPolarHBondContact CA-OD1 3.46Å; K356-D361 WeakPolarHBondContact CB-OD1 3.36Å; F359-D361 VanDerWaalsContact C-N 3.26Å; F359-D361 PolarHBondContact O-N 3.49Å; D361-L366 HydrophobicContact CB-CD1 4.3Å; D361-L366 VanDerWaalsContact O-CD1 3.28Å; D361-L366 WeakPolarHBondContact O-CD1 3.41Å
362D97.1Very high96.9Very high24 Ų2452.9 Ų52.913%0.12826%0.259CS..  trans-54.4129175-179.6-75.2000110.7F297 F359 Q360 R364 F365 L366F297-D362 HydrophobicContact CZ-CB 4.12Å; F297-D362 WeakPolarHBondContact CZ-OD2 3.13Å; F359-D362 HydrophobicContact CB-CB 4.49Å; F359-D362 VanDerWaalsContact O-CB 3.25Å; F359-D362 WeakPolarHBondContact O-CB 3.33Å; F359-D362 PolarHBondContact O-N 3.38Å; Q360-D362 PolarHBondContact O-N 3.39Å; D362-R364 PolarHBondContact O-N 3.2Å; D362-R364 VanDerWaalsContact O-N 3.08Å; D362-R364 WeakPolarHBondContact OD1-CA 3.41Å; D362-R364 WeakPolarHBondContact OD1-CB 2.97Å; D362-R364 WeakPolarHBondContact OD1-CG 3.38Å; D362-R364 IonicContact OD1-CZ 3.62Å; D362-R364 PolarHBondContact OD1-N 3.38Å; D362-R364 IonicContact OD1-NE 3.57Å; D362-R364 PolarHBondContact OD1-NE 2.95Å; D362-R364 IonicContact OD1-NH2 3.22Å; D362-R364 IonicContact OD2-CZ 3.93Å; D362-R364 IonicContact OD2-NE 2.82Å; D362-R364 PolarHBondContact OD2-NE 2.89Å; D362-R364 IonicContact OD2-NH2 3.9Å; D362-R364 PolarHBondContact OD2-NH2 2.93Å; D362-F365 HydrophobicContact CB-CD2 3.94Å; D362-F365 PolarHBondContact O-N 3.43Å; D362-L366 PolarHBondContact O-N 2.82Å
363P97.3Very high96.9Very high91 Ų9152.1 Ų52.159%0.59125%0.253SS*.Hα-helixtrans-55.9-29.9-175.3-28.735.3000114.8T367P363-T367 WeakPolarHBondContact O-CB 3.48Å; P363-T367 PolarHBondContact O-N 3.46Å; P363-T367 PolarHBondContact O-OG1 3.19Å
364R97.2Very high96.8Very high91 Ų9150.5 Ų50.534%0.34325%0.246SC..Hα-helixtrans-70.2-41.7179.9-57166.7-73.9-173-2.8110D301 I307 L311 D362 T367 A368D301-R364 IonicContact OD1-CZ 3.52Å; D301-R364 VanDerWaalsContact OD1-CZ 3.25Å; D301-R364 IonicContact OD1-NH1 2.66Å; D301-R364 PolarHBondContact OD1-NH1 3.49Å; D301-R364 IonicContact OD1-NH2 2.96Å; D301-R364 PolarHBondContact OD1-NH2 3.23Å; D301-R364 IonicContact OD2-NH2 3.31Å; I307-R364 VanDerWaalsContact CD1-CD 3.45Å; L311-R364 HydrophobicContact CD1-CB 4.32Å; L311-R364 HydrophobicContact CD2-CB 4.06Å; D362-R364 PolarHBondContact O-N 3.2Å; D362-R364 VanDerWaalsContact O-N 3.08Å; D362-R364 WeakPolarHBondContact OD1-CA 3.41Å; D362-R364 WeakPolarHBondContact OD1-CB 2.97Å; D362-R364 WeakPolarHBondContact OD1-CG 3.38Å; D362-R364 IonicContact OD1-CZ 3.62Å; D362-R364 PolarHBondContact OD1-N 3.38Å; D362-R364 IonicContact OD1-NE 3.57Å; D362-R364 PolarHBondContact OD1-NE 2.95Å; D362-R364 IonicContact OD1-NH2 3.22Å; D362-R364 IonicContact OD2-CZ 3.93Å; D362-R364 IonicContact OD2-NE 2.82Å; D362-R364 PolarHBondContact OD2-NE 2.89Å; D362-R364 IonicContact OD2-NH2 3.9Å; D362-R364 PolarHBondContact OD2-NH2 2.93Å; R364-T367 PolarHBondContact O-N 2.9Å; R364-A368 PolarHBondContact O-N 3.26Å
365F97.7Very high96.6Very high0 Ų052.3 Ų52.30%026%0.262CS..Hα-helixtrans-74.2-33.4176.2-72-88.7000113F297 M310 L311 L314 V355 F359 D362 T367 A368 R369F297-F365 AromaticContact CD2-CE2 3.65Å; F297-F365 HydrophobicContact CD2-CE2 3.65Å; F297-F365 HydrophobicContact CD2-CZ 4.14Å; F297-F365 HydrophobicContact CE2-CD2 4.45Å; F297-F365 AromaticContact CE2-CE2 3.7Å; F297-F365 HydrophobicContact CE2-CE2 3.7Å; F297-F365 HydrophobicContact CG-CE2 4.47Å; M310-F365 HydrophobicContact CB-CE1 4.08Å; M310-F365 HydrophobicContact CB-CZ 4.02Å; M310-F365 HydrophobicContact CE-CZ 4.37Å; L311-F365 HydrophobicContact CD2-CB 4.44Å; L311-F365 HydrophobicContact CD2-CD1 3.7Å; L311-F365 HydrophobicContact CD2-CD2 3.97Å; L311-F365 HydrophobicContact CD2-CE1 3.87Å; L311-F365 HydrophobicContact CD2-CE2 4.13Å; L311-F365 HydrophobicContact CD2-CG 3.78Å; L311-F365 HydrophobicContact CD2-CZ 4.09Å; L314-F365 HydrophobicContact CD2-CB 4.36Å; L314-F365 HydrophobicContact CD2-CD1 3.73Å; V355-F365 HydrophobicContact CG1-CB 3.93Å; F359-F365 HydrophobicContact CB-CB 4.05Å; F359-F365 HydrophobicContact CB-CD1 4.32Å; F359-F365 HydrophobicContact CB-CD2 3.81Å; F359-F365 HydrophobicContact CB-CE2 4.31Å; F359-F365 HydrophobicContact CB-CG 3.79Å; F359-F365 AromaticContact CD1-CD1 3.98Å; F359-F365 HydrophobicContact CD1-CD1 3.98Å; F359-F365 HydrophobicContact CD1-CD2 4.16Å; F359-F365 AromaticContact CD1-CE1 3.69Å; F359-F365 HydrophobicContact CD1-CE1 3.69Å; F359-F365 AromaticContact CD1-CE2 3.88Å; F359-F365 HydrophobicContact CD1-CE2 3.88Å; F359-F365 HydrophobicContact CD1-CG 4.19Å; F359-F365 AromaticContact CD1-CZ 3.62Å; F359-F365 HydrophobicContact CD1-CZ 3.62Å; F359-F365 HydrophobicContact CD2-CB 4.03Å; F359-F365 AromaticContact CD2-CD1 3.37Å; F359-F365 HydrophobicContact CD2-CD1 3.37Å; F359-F365 HydrophobicContact CD2-CD2 4.4Å; F359-F365 AromaticContact CD2-CE1 3.84Å; F359-F365 HydrophobicContact CD2-CE1 3.84Å; F359-F365 AromaticContact CD2-CG 3.68Å; F359-F365 HydrophobicContact CD2-CG 3.68Å; F359-F365 HydrophobicContact CE1-CD1 4.14Å; F359-F365 AromaticContact CE1-CE1 3.57Å; F359-F365 HydrophobicContact CE1-CE1 3.57Å; F359-F365 HydrophobicContact CE1-CE2 4.45Å; F359-F365 AromaticContact CE1-CZ 3.74Å; F359-F365 HydrophobicContact CE1-CZ 3.74Å; F359-F365 AromaticContact CE2-CD1 3.56Å; F359-F365 HydrophobicContact CE2-CD1 3.56Å; F359-F365 AromaticContact CE2-CE1 3.73Å; F359-F365 HydrophobicContact CE2-CE1 3.73Å; F359-F365 HydrophobicContact CE2-CG 4.34Å; F359-F365 HydrophobicContact CG-CB 4.19Å; F359-F365 AromaticContact CG-CD1 3.61Å; F359-F365 HydrophobicContact CG-CD1 3.61Å; F359-F365 AromaticContact CG-CD2 3.86Å; F359-F365 HydrophobicContact CG-CD2 3.86Å; F359-F365 AromaticContact CG-CE1 3.84Å; F359-F365 HydrophobicContact CG-CE1 3.84Å; F359-F365 HydrophobicContact CG-CE2 4.07Å; F359-F365 AromaticContact CG-CG 3.61Å; F359-F365 HydrophobicContact CG-CG 3.61Å; F359-F365 HydrophobicContact CG-CZ 4.06Å; F359-F365 AromaticContact CZ-CD1 3.95Å; F359-F365 HydrophobicContact CZ-CD1 3.95Å; F359-F365 AromaticContact CZ-CE1 3.58Å; F359-F365 HydrophobicContact CZ-CE1 3.58Å; F359-F365 HydrophobicContact CZ-CZ 4.24Å; D362-F365 HydrophobicContact CB-CD2 3.94Å; D362-F365 PolarHBondContact O-N 3.43Å; F365-T367 VanDerWaalsContact C-N 3.34Å; F365-A368 PolarHBondContact O-N 3.17Å; F365-R369 WeakPolarHBondContact O-CB 3.17Å; F365-R369 PolarHBondContact O-N 3.47Å
366L97.3Very high96.4Very high44 Ų4452.7 Ų52.723%0.2326%0.264CS..Hα-helixtrans-61.5-43.6170.3-70173.9000111.3V355 D361 D362 R369 D370V355-L366 HydrophobicContact CG1-CD2 3.81Å; V355-L366 HydrophobicContact CG1-CG 4.17Å; D361-L366 HydrophobicContact CB-CD1 4.3Å; D361-L366 VanDerWaalsContact O-CD1 3.28Å; D361-L366 WeakPolarHBondContact O-CD1 3.41Å; D362-L366 PolarHBondContact O-N 2.82Å; L366-R369 PolarHBondContact O-N 3.36Å; L366-D370 WeakPolarHBondContact O-CB 3.43Å; L366-D370 VanDerWaalsContact O-CG 3.23Å; L366-D370 PolarHBondContact O-N 2.99Å
367T97.4Very high96.2Very high92 Ų9246.4 Ų46.456%0.56424%0.236SC*.Hα-helixtrans-63.2-43.3176.2-57.40000111.7P363 R364 F365 D370 K371P363-T367 WeakPolarHBondContact O-CB 3.48Å; P363-T367 PolarHBondContact O-N 3.46Å; P363-T367 PolarHBondContact O-OG1 3.19Å; R364-T367 PolarHBondContact O-N 2.9Å; F365-T367 VanDerWaalsContact C-N 3.34Å; T367-D370 PolarHBondContact O-N 3.35Å; T367-K371 WeakPolarHBondContact O-CB 3.27Å; T367-K371 PolarHBondContact O-N 2.93Å
368A97.2Very high96Very high2 Ų243.5 Ų43.52%0.01722%0.224CC..Hα-helixtrans-60.1-46.6174.900000111.7L311 E315 R364 F365 D370 K371 A372L311-A368 HydrophobicContact CD2-CB 4.03Å; E315-A368 HydrophobicContact CG-CB 3.81Å; R364-A368 PolarHBondContact O-N 3.26Å; F365-A368 PolarHBondContact O-N 3.17Å; A368-D370 PolarHBondContact O-N 3.08Å; A368-K371 PolarHBondContact O-N 2.91Å; A368-A372 VanDerWaalsContact O-CB 3.3Å; A368-A372 WeakPolarHBondContact O-CB 3.47Å; A368-A372 PolarHBondContact O-N 3.32Å
369R97.5Very high95.5Very high27 Ų2745.5 Ų45.510%0.10224%0.235CC..Hα-helixtrans-57-48.1173.7178.9-150.563.6-158.5-14111.5I318 F351 S352 V355 F365 L366 K371 A372 Y373I318-R369 HydrophobicContact CD1-CB 3.99Å; I318-R369 HydrophobicContact CD1-CG 4.01Å; F351-R369 HydrophobicContact CB-CG 4.3Å; S352-R369 WeakPolarHBondContact OG-CD 3.32Å; S352-R369 PolarHBondContact OG-NH1 2.91Å; V355-R369 HydrophobicContact CG2-CB 4.1Å; F365-R369 WeakPolarHBondContact O-CB 3.17Å; F365-R369 PolarHBondContact O-N 3.47Å; L366-R369 PolarHBondContact O-N 3.36Å; R369-K371 PolarHBondContact O-N 2.7Å; R369-A372 PolarHBondContact O-N 3.09Å; R369-Y373 VanDerWaalsContact O-CB 3.22Å; R369-Y373 WeakPolarHBondContact O-CB 3.49Å; R369-Y373 PolarHBondContact O-N 3.23Å
370D96.9Very high94.8Very high48 Ų4846.5 Ų46.526%0.25724%0.243SC..Hα-helixtrans-65.4-40.3-176.9-72-9.2000112.1L366 T367 A368 K374 Y443L366-D370 WeakPolarHBondContact O-CB 3.43Å; L366-D370 VanDerWaalsContact O-CG 3.23Å; L366-D370 PolarHBondContact O-N 2.99Å; T367-D370 PolarHBondContact O-N 3.35Å; A368-D370 PolarHBondContact O-N 3.08Å; D370-K374 WeakPolarHBondContact O-CB 3.42Å; D370-K374 PolarHBondContact O-N 3.31Å; D370-Y443 HydrophobicContact CB-CE1 3.88Å; D370-Y443 PolarHBondContact OD1-OH 2.97Å
371K95.8Very high93.8Very high126 Ų12644.6 Ų44.655%0.54824%0.24SC..Hα-helixtrans-63.3-45.8174-178.9-179.3164.9-1480111.6E315 T367 A368 R369 K374 A375E315-K371 VanDerWaalsContact CD-NZ 3.33Å; E315-K371 WeakPolarHBondContact OE1-CD 3.37Å; E315-K371 IonicContact OE1-NZ 2.6Å; E315-K371 PolarHBondContact OE1-NZ 3.24Å; E315-K371 VanDerWaalsContact OE1-NZ 3.11Å; E315-K371 WeakPolarHBondContact OE2-CE 3.39Å; E315-K371 IonicContact OE2-NZ 2.7Å; E315-K371 PolarHBondContact OE2-NZ 2.9Å; T367-K371 WeakPolarHBondContact O-CB 3.27Å; T367-K371 PolarHBondContact O-N 2.93Å; A368-K371 PolarHBondContact O-N 2.91Å; R369-K371 PolarHBondContact O-N 2.7Å; K371-K374 PolarHBondContact O-N 3.24Å; K371-A375 PolarHBondContact O-N 2.97Å
372A96.7Very high92.4Very high0 Ų043.3 Ų43.30%023%0.233CC..Hα-helixtrans-69-42.8179.500000112.4E315 I318 I319 A368 R369 K374 A375 V376E315-A372 HydrophobicContact CB-CB 4.25Å; E315-A372 HydrophobicContact CG-CB 4.35Å; I318-A372 HydrophobicContact CB-CB 3.65Å; I318-A372 HydrophobicContact CD1-CB 4.23Å; I318-A372 HydrophobicContact CG2-CB 3.48Å; I318-A372 VanDerWaalsContact CG2-CB 3.48Å; I319-A372 HydrophobicContact CD1-CB 4.41Å; I319-A372 HydrophobicContact CG1-CB 3.99Å; A368-A372 VanDerWaalsContact O-CB 3.3Å; A368-A372 WeakPolarHBondContact O-CB 3.47Å; A368-A372 PolarHBondContact O-N 3.32Å; R369-A372 PolarHBondContact O-N 3.09Å; A372-K374 VanDerWaalsContact C-N 3.34Å; A372-K374 PolarHBondContact O-N 2.92Å; A372-A375 WeakPolarHBondContact O-CB 3.3Å; A372-A375 PolarHBondContact O-N 3.22Å; A372-A375 VanDerWaalsContact O-N 3.08Å; A372-V376 PolarHBondContact O-N 2.95Å
373Y96.7Very high91Very high3 Ų343.1 Ų43.11%0.01223%0.231CC..Hα-helixtrans-62.7-41.3174.8-173.2-103.1000111.4L344 L347 F348 R369 A375 V376 V377 Y443L344-Y373 WeakPolarHBondContact O-CE2 3.28Å; L344-Y373 PolarHBondContact O-OH 2.79Å; L347-Y373 HydrophobicContact CB-CE2 4.33Å; F348-Y373 HydrophobicContact CB-CD2 4.3Å; F348-Y373 HydrophobicContact CB-CE1 4.44Å; F348-Y373 HydrophobicContact CB-CE2 3.64Å; F348-Y373 AromaticContact CD2-CD1 3.89Å; F348-Y373 HydrophobicContact CD2-CD1 3.89Å; F348-Y373 HydrophobicContact CD2-CD2 4.16Å; F348-Y373 AromaticContact CD2-CE1 3.85Å; F348-Y373 HydrophobicContact CD2-CE1 3.85Å; F348-Y373 HydrophobicContact CD2-CE2 4.13Å; F348-Y373 HydrophobicContact CD2-CG 4.05Å; F348-Y373 AromaticContact CD2-CZ 3.97Å; F348-Y373 HydrophobicContact CG-CE2 4.4Å; R369-Y373 VanDerWaalsContact O-CB 3.22Å; R369-Y373 WeakPolarHBondContact O-CB 3.49Å; R369-Y373 PolarHBondContact O-N 3.23Å; Y373-A375 VanDerWaalsContact C-N 3.28Å; Y373-A375 PolarHBondContact O-N 3.45Å; Y373-V376 PolarHBondContact O-N 3.32Å; Y373-V376 VanDerWaalsContact O-N 3.16Å; Y373-V377 HydrophobicContact CD1-CG2 3.91Å; Y373-V377 HydrophobicContact CE1-CG2 3.51Å; Y373-V377 HydrophobicContact CE2-CG2 4.37Å; Y373-V377 HydrophobicContact CG-CG2 4.48Å; Y373-V377 WeakPolarHBondContact O-CG2 3.48Å; Y373-V377 PolarHBondContact O-N 2.97Å; Y373-Y443 HydrophobicContact CD1-CD1 4Å; Y373-Y443 AromaticContact CD1-CD2 3.6Å; Y373-Y443 HydrophobicContact CD1-CD2 3.6Å; Y373-Y443 HydrophobicContact CD1-CE1 4.34Å; Y373-Y443 AromaticContact CD1-CE2 3.96Å; Y373-Y443 HydrophobicContact CD1-CE2 3.96Å; Y373-Y443 AromaticContact CD1-CG 3.62Å; Y373-Y443 HydrophobicContact CD1-CG 3.62Å; Y373-Y443 AromaticContact CE1-CD2 3.56Å; Y373-Y443 HydrophobicContact CE1-CD2 3.56Å; Y373-Y443 HydrophobicContact CE1-CE2 4.03Å; Y373-Y443 AromaticContact CE1-CG 3.97Å; Y373-Y443 HydrophobicContact CE1-CG 3.97Å
374K94.4Very high89.5Confident87 Ų8744.6 Ų44.638%0.37823%0.228SC..Hα-helixtrans-58-39.3171.1-177.3169.6-170.9177.40112D370 K371 A372 N378 Y443D370-K374 WeakPolarHBondContact O-CB 3.42Å; D370-K374 PolarHBondContact O-N 3.31Å; K371-K374 PolarHBondContact O-N 3.24Å; A372-K374 VanDerWaalsContact C-N 3.34Å; A372-K374 PolarHBondContact O-N 2.92Å; K374-N378 WeakPolarHBondContact CG-ND2 3.38Å; K374-N378 WeakPolarHBondContact O-CB 3.22Å; K374-N378 PolarHBondContact O-N 3.34Å; K374-N378 VanDerWaalsContact O-N 3.15Å; K374-N378 PolarHBondContact O-ND2 2.99Å; K374-Y443 HydrophobicContact CB-CD1 4.3Å; K374-Y443 WeakPolarHBondContact CG-O 3.45Å
375A93.4Very high87.9Confident43 Ų4340.7 Ų40.736%0.35521%0.214SC..Hα-helixtrans-64-43.2175.300000111.7I319 K371 A372 Y373 D379I319-A375 HydrophobicContact CD1-CB 3.9Å; I319-A375 HydrophobicContact CG1-CB 4.01Å; K371-A375 PolarHBondContact O-N 2.97Å; A372-A375 WeakPolarHBondContact O-CB 3.3Å; A372-A375 PolarHBondContact O-N 3.22Å; A372-A375 VanDerWaalsContact O-N 3.08Å; Y373-A375 VanDerWaalsContact C-N 3.28Å; Y373-A375 PolarHBondContact O-N 3.45Å; A375-D379 WeakPolarHBondContact O-CB 3.43Å; A375-D379 PolarHBondContact O-N 3.33Å
376V93.1Very high86.2Confident8 Ų847 Ų475%0.04824%0.243CC..Hα-helixtrans-63.3-47176.6178.30000112L323 M326 L347 A372 Y373 N378 D379L323-V376 HydrophobicContact CD2-CG1 4.43Å; M326-V376 HydrophobicContact CG-CG1 4.31Å; L347-V376 HydrophobicContact CD1-CG1 4.4Å; A372-V376 PolarHBondContact O-N 2.95Å; Y373-V376 PolarHBondContact O-N 3.32Å; Y373-V376 VanDerWaalsContact O-N 3.16Å; V376-N378 VanDerWaalsContact C-N 3.3Å; V376-N378 PolarHBondContact O-N 2.92Å; V376-D379 WeakPolarHBondContact O-CB 3.41Å; V376-D379 PolarHBondContact O-N 3Å
377V92.8Very high84.6Confident0 Ų044.9 Ų44.90%023%0.233CC..Hα-helixtrans-62.4-36.8-178.7168.80000112.3L344 Y373 S402 C404 V440 V444L344-V377 HydrophobicContact CD2-CG2 4.23Å; Y373-V377 HydrophobicContact CD1-CG2 3.91Å; Y373-V377 HydrophobicContact CE1-CG2 3.51Å; Y373-V377 HydrophobicContact CE2-CG2 4.37Å; Y373-V377 HydrophobicContact CG-CG2 4.48Å; Y373-V377 WeakPolarHBondContact O-CG2 3.48Å; Y373-V377 PolarHBondContact O-N 2.97Å; V377-S402 PolarHBondContact O-OG 3.15Å; V377-C404 WeakPolarHBondContact O-CB 3.43Å; V377-V440 HydrophobicContact CG1-CG1 4.41Å; V377-V440 HydrophobicContact CG2-CG1 4.29Å; V377-V444 HydrophobicContact CG1-CG2 3.83Å
378N91.2Very high82.7Confident26 Ų2642.8 Ų42.814%0.13922%0.22CC..THydrogen-bonded Turntrans-95.96.2-179.1-61.6-78.5000113.3K374 V376 A380 Y443 Q445K374-N378 WeakPolarHBondContact CG-ND2 3.38Å; K374-N378 WeakPolarHBondContact O-CB 3.22Å; K374-N378 PolarHBondContact O-N 3.34Å; K374-N378 VanDerWaalsContact O-N 3.15Å; K374-N378 PolarHBondContact O-ND2 2.99Å; V376-N378 VanDerWaalsContact C-N 3.3Å; V376-N378 PolarHBondContact O-N 2.92Å; N378-A380 PolarHBondContact O-N 3.39Å; N378-Y443 PolarHBondContact ND2-O 3.35Å; N378-Q445 HydrophobicContact CB-CG 4.35Å; N378-Q445 WeakPolarHBondContact OD1-CB 3.47Å; N378-Q445 PolarHBondContact OD1-N 2.92Å
379D87.1Confident80.6Confident42 Ų4245 Ų4523%0.22523%0.231CC..  trans-68129.8176.6-173.9-94000110.6L323 A375 V376 T381L323-D379 HydrophobicContact CD2-CB 3.54Å; L323-D379 VanDerWaalsContact CD2-CG 3.44Å; A375-D379 WeakPolarHBondContact O-CB 3.43Å; A375-D379 PolarHBondContact O-N 3.33Å; V376-D379 WeakPolarHBondContact O-CB 3.41Å; V376-D379 PolarHBondContact O-N 3Å; D379-T381 WeakPolarHBondContact OD1-CA 3.29Å; D379-T381 WeakPolarHBondContact OD1-CB 3.36Å; D379-T381 WeakPolarHBondContact OD1-CG2 3.44Å; D379-T381 PolarHBondContact OD1-N 2.74Å; D379-T381 PolarHBondContact OD1-OG1 3.17Å
380A82.7Confident78.5Confident20 Ų2050.2 Ų50.217%0.16526%0.255CS..  trans-99.56.3-179.300000112.3N378 K384 P400N378-A380 PolarHBondContact O-N 3.39Å; A380-K384 HydrophobicContact CB-CG 4.46Å; A380-K384 WeakPolarHBondContact O-CE 3.4Å; A380-K384 WeakPolarHBondContact O-CG 3.49Å; A380-P400 HydrophobicContact CB-CB 4.27Å
381T73.3Confident76.3Confident94 Ų9453.7 Ų53.758%0.57727%0.27SS*.SBendtrans-73-32.5-177680000112.3D379D379-T381 WeakPolarHBondContact OD1-CA 3.29Å; D379-T381 WeakPolarHBondContact OD1-CB 3.36Å; D379-T381 WeakPolarHBondContact OD1-CG2 3.44Å; D379-T381 PolarHBondContact OD1-N 2.74Å; D379-T381 PolarHBondContact OD1-OG1 3.17Å
382I67.7Low73.8Confident41 Ų4158.3 Ų58.321%0.2129%0.29CS..SBendtrans-90.2-48.9-176.5-49.1179.8000110.7L323 M326 V327L323-I382 HydrophobicContact CD2-CD1 4.26Å; M326-I382 HydrophobicContact CB-CD1 3.1Å; M326-I382 HydrophobicContact CG-CD1 4.11Å; V327-I382 HydrophobicContact CG2-CD1 3.75Å; V327-I382 HydrophobicContact CG2-CG1 3.85Å
383F66.7Low71.3Confident20 Ų2062 Ų629%0.08833%0.328CS..SBendtrans-127.4104.1-178.4-70.8-73.8000111.5I333 T334 Y340 K403I333-F383 HydrophobicContact CD1-CE2 3.87Å; I333-F383 HydrophobicContact CD1-CZ 4.37Å; I333-F383 HydrophobicContact CG1-CE2 3.78Å; I333-F383 HydrophobicContact CG1-CZ 3.77Å; T334-F383 HydrophobicContact CG2-CD1 4.49Å; T334-F383 HydrophobicContact CG2-CE1 3.3Å; T334-F383 HydrophobicContact CG2-CZ 3.41Å; T334-F383 VanDerWaalsContact CG2-CZ 3.41Å; Y340-F383 HydrophobicContact CD2-CD2 4.16Å; Y340-F383 AromaticContact CD2-CE2 3.7Å; Y340-F383 HydrophobicContact CD2-CE2 3.7Å; Y340-F383 HydrophobicContact CD2-CZ 4.35Å; Y340-F383 AromaticContact CE2-CD2 3.51Å; Y340-F383 HydrophobicContact CE2-CD2 3.51Å; Y340-F383 AromaticContact CE2-CE2 3.49Å; Y340-F383 HydrophobicContact CE2-CE2 3.49Å; Y340-F383 VanDerWaalsContact CE2-CE2 3.49Å; Y340-F383 HydrophobicContact CE2-CZ 4.49Å; F383-K403 HydrophobicContact CB-CB 3.68Å; F383-K403 PolarHBondContact O-N 2.87Å; F383-K403 VanDerWaalsContact O-N 3.12Å
384K67.2Low68.7Low122 Ų12266.3 Ų66.353%0.5335%0.354SS..EExtended strand (participates in β ladder)trans-92.7124.6176.8-65.8179.2-175.81770110.2A380 P400 E401A380-K384 HydrophobicContact CB-CG 4.46Å; A380-K384 WeakPolarHBondContact O-CE 3.4Å; A380-K384 WeakPolarHBondContact O-CG 3.49Å; K384-P400 HydrophobicContact CB-CB 4.07Å; K384-P400 HydrophobicContact CD-CB 3.87Å; K384-P400 HydrophobicContact CD-CG 4.15Å; K384-P400 HydrophobicContact CG-CB 3.79Å; K384-E401 CarbonylContact C-O 3.51Å
385L63.1Low66.1Low10 Ų1066.2 Ų66.25%0.05238%0.378CS..EExtended strand (participates in β ladder)trans-95.2116.1158.5-176.669.6000107.2L387 E401 V449L385-L387 HydrophobicContact CD2-CD2 3.99Å; L385-L387 HydrophobicContact CD2-CG 4.23Å; L385-L387 HydrophobicContact CG-CD2 4.17Å; L385-L387 HydrophobicContact CG-CG 4.3Å; L385-E401 HydrophobicContact CB-CB 4.44Å; L385-E401 PolarHBondContact N-O 2.9Å; L385-E401 PolarHBondContact O-N 3.45Å; L385-V449 HydrophobicContact CD2-CG1 3.75Å; L385-V449 HydrophobicContact CD2-CG2 4.32Å
386E62.7Low63.8Low131 Ų13166.1 Ų66.161%0.61237%0.371SS*.PPolyproline II helixtrans-96.3119.8168.5-65.4-170.3162.200108.1P388E386-P388 WeakPolarHBondContact O-CD 3.4Å
387L62.2Low61.9Low1 Ų175.2 Ų75.21%0.00541%0.41CS..  trans-97.988.6174.9-67174.1000108.1L385 L389 T398 N704 I707 V708L385-L387 HydrophobicContact CD2-CD2 3.99Å; L385-L387 HydrophobicContact CD2-CG 4.23Å; L385-L387 HydrophobicContact CG-CD2 4.17Å; L385-L387 HydrophobicContact CG-CG 4.3Å; L387-L389 PolarHBondContact O-N 3.15Å; L387-T398 PolarHBondContact N-OG1 3.45Å; L387-T398 WeakPolarHBondContact O-CG2 3.39Å; L387-T398 PolarHBondContact O-OG1 3.48Å; L387-N704 HydrophobicContact CD2-CB 3.64Å; L387-N704 VanDerWaalsContact CD2-CG 3.49Å; L387-N704 WeakPolarHBondContact CD2-OD1 3.41Å; L387-I707 HydrophobicContact CD1-CG2 4.25Å; L387-I707 HydrophobicContact CD2-CD1 4.34Å; L387-V708 HydrophobicContact CB-CG2 3.84Å; L387-V708 HydrophobicContact CD1-CG2 4.31Å
388P59.3Low60.3Low47 Ų4776.4 Ų76.431%0.30542%0.417SS..  trans-59.9133.8-174.923.6-33.4000111.7E386E386-P388 WeakPolarHBondContact O-CD 3.4Å
389L52.6Low59Low48 Ų4881.4 Ų81.425%0.25144%0.44SS..  trans-100.695168.3-89.8164.9000108.5L387 Q391 T398 V708L387-L389 PolarHBondContact O-N 3.15Å; L389-Q391 PolarHBondContact O-N 2.77Å; L389-Q391 VanDerWaalsContact O-N 3.08Å; L389-T398 HydrophobicContact CB-CG2 4.44Å; L389-T398 HydrophobicContact CD1-CG2 3.57Å; L389-T398 HydrophobicContact CG-CG2 3.93Å; L389-V708 HydrophobicContact CD1-CG1 4.11Å; L389-V708 HydrophobicContact CD2-CB 4.15Å; L389-V708 HydrophobicContact CD2-CG1 3.38Å; L389-V708 HydrophobicContact CG-CG1 3.81Å
390K52.4Low58.2Low137 Ų13781.5 Ų81.560%0.59644%0.443SS*.  trans-8267.6165.5-71.3-178.3-172.4157.20110.1K392 E701K390-K392 PolarHBondContact O-N 2.91Å; K390-E701 IonicContact NZ-OE2 3.39Å; K390-E701 PolarHBondContact NZ-OE2 3.47Å
391Q50.7Low58.1Low121 Ų12181.2 Ų81.257%0.56544%0.438SS*.  trans-80.1114.9157.1-80-173.4-7.100107.9L389 G393 V394L389-Q391 PolarHBondContact O-N 2.77Å; L389-Q391 VanDerWaalsContact O-N 3.08Å; Q391-G393 PolarHBondContact O-N 3.31Å; Q391-V394 PolarHBondContact O-N 2.93Å
392K43.7Very low58.6Low224 Ų22477.2 Ų77.297%0.97441%0.414SS*.THydrogen-bonded Turntrans-49.9107.2172.5-78.1-178.3173.9178.90109K390K390-K392 PolarHBondContact O-N 2.91Å
393G45Very low59.4Low77 Ų7778.3 Ų78.379%0.79442%0.417SS*.THydrogen-bonded Turntrans126.4-15.6168.200000117Q391Q391-G393 PolarHBondContact O-N 3.31Å
394V40.7Very low60.5Low93 Ų9377.4 Ų77.456%0.56441%0.413SS*.  trans-144115.8177-156.40000109.8Q391 L396Q391-V394 PolarHBondContact O-N 2.93Å; V394-L396 HydrophobicContact CB-CD1 3.43Å; V394-L396 VanDerWaalsContact CB-CD1 3.43Å; V394-L396 HydrophobicContact CG1-CD1 3.25Å; V394-L396 PolarHBondContact O-N 3.05Å
395G39.7Very low61.7Low85 Ų8571.7 Ų71.788%0.87639%0.388SS*.  trans-68.662-179.200000113.8K397G395-K397 PolarHBondContact O-N 3.49Å
396L46.7Very low62.9Low42 Ų4272.6 Ų72.622%0.2239%0.392CS..  trans-76.8102.8177.4-88.481.6000110V394 T398V394-L396 HydrophobicContact CB-CD1 3.43Å; V394-L396 VanDerWaalsContact CB-CD1 3.43Å; V394-L396 HydrophobicContact CG1-CD1 3.25Å; V394-L396 PolarHBondContact O-N 3.05Å; L396-T398 PolarHBondContact O-N 3.41Å
397K52.4Low64.2Low199 Ų19966.7 Ų66.787%0.86537%0.365SS*.PPolyproline II helixtrans-66125.6158.2-63.6-174.7178.2-173.80108.5G395G395-K397 PolarHBondContact O-N 3.49Å
398T59.1Low65.7Low24 Ų2466.7 Ų66.715%0.14737%0.365CS..PPolyproline II helixtrans-70.3153.3168.251.90000110.1L387 L389 L396L387-T398 PolarHBondContact N-OG1 3.45Å; L387-T398 WeakPolarHBondContact O-CG2 3.39Å; L387-T398 PolarHBondContact O-OG1 3.48Å; L389-T398 HydrophobicContact CB-CG2 4.44Å; L389-T398 HydrophobicContact CD1-CG2 3.57Å; L389-T398 HydrophobicContact CG-CG2 3.93Å; L396-T398 PolarHBondContact O-N 3.41Å
399Q64.1Low67.3Low132 Ų13264.4 Ų64.462%0.61735%0.35SS*.PPolyproline II helixtrans-59.2136.9167.8-75.8-69.5-13.800109.7E401Q399-E401 PolarHBondContact O-N 2.9Å
400P71.1Confident69.1Low43 Ų4363.9 Ų63.928%0.27935%0.347SS..PPolyproline II helixtrans-58.9132.6173.4-20.731.6000110.5A380 K384A380-P400 HydrophobicContact CB-CB 4.27Å; K384-P400 HydrophobicContact CB-CB 4.07Å; K384-P400 HydrophobicContact CD-CB 3.87Å; K384-P400 HydrophobicContact CD-CG 4.15Å; K384-P400 HydrophobicContact CG-CB 3.79Å
401E80.7Confident71.1Confident15 Ų1557.5 Ų57.57%0.0732%0.32CS..EExtended strand (participates in β ladder)trans-107.4160.5174.8-61-172.4178.300110K384 L385 Q399 N446 R711 Q749K384-E401 CarbonylContact C-O 3.51Å; L385-E401 HydrophobicContact CB-CB 4.44Å; L385-E401 PolarHBondContact N-O 2.9Å; L385-E401 PolarHBondContact O-N 3.45Å; Q399-E401 PolarHBondContact O-N 2.9Å; E401-N446 PolarHBondContact OE2-ND2 3.36Å; E401-R711 IonicContact OE1-CZ 2.79Å; E401-R711 IonicContact OE1-NH1 3.23Å; E401-R711 PolarHBondContact OE1-NH1 3.38Å; E401-R711 IonicContact OE1-NH2 2.79Å; E401-R711 IonicContact OE2-CZ 2.99Å; E401-R711 IonicContact OE2-NH1 3.88Å; E401-R711 PolarHBondContact OE2-NH1 2.92Å; E401-R711 IonicContact OE2-NH2 2.75Å; E401-R711 PolarHBondContact OE2-NH2 3.43Å; E401-Q749 PolarHBondContact OE1-NE2 3.1Å
402S83.1Confident73.2Confident9 Ų951.8 Ų51.86%0.06329%0.293CS..EExtended strand (participates in β ladder)trans-66.8136174.7171.80000110.6V377 C404 P405V377-S402 PolarHBondContact O-OG 3.15Å; S402-C404 PolarHBondContact O-N 3.49Å; S402-C404 WeakPolarHBondContact OG-CB 3.46Å; S402-C404 PolarHBondContact OG-N 3.31Å; S402-C404 VanDerWaalsContact OG-N 3.13Å; S402-P405 WeakPolarHBondContact O-CD 3.49Å
403K85.1Confident75.6Confident65 Ų6541.4 Ų41.428%0.28325%0.248SC..SBendtrans-76.5-5172.1-154.2177.8179.4179.40113.4F383 E406 L407F383-K403 HydrophobicContact CB-CB 3.68Å; F383-K403 PolarHBondContact O-N 2.87Å; F383-K403 VanDerWaalsContact O-N 3.12Å; K403-E406 VanDerWaalsContact CE-OE1 3.24Å; K403-E406 WeakPolarHBondContact CE-OE1 3.22Å; K403-E406 WeakPolarHBondContact CE-OE2 3.3Å; K403-E406 HydrophobicContact CG-CB 4.22Å; K403-E406 WeakPolarHBondContact CG-OE2 3.46Å; K403-E406 IonicContact NZ-OE1 2.73Å; K403-E406 PolarHBondContact O-N 3.05Å; K403-E406 VanDerWaalsContact O-N 3.11Å; K403-L407 HydrophobicContact CG-CG 4.45Å; K403-L407 PolarHBondContact O-N 3.47Å; K403-L407 VanDerWaalsContact O-N 3.15Å
404C89.9Confident77.8Confident0 Ų040.2 Ų40.20%022%0.222CC..Hα-helixtrans-47.2-46.5179.3-174.70000114.1Y340 V377 S402 E406 L407 L408Y340-C404 HydrophobicContact CE1-CB 4.22Å; Y340-C404 WeakPolarHBondContact OH-CB 3.4Å; V377-C404 WeakPolarHBondContact O-CB 3.43Å; S402-C404 PolarHBondContact O-N 3.49Å; S402-C404 WeakPolarHBondContact OG-CB 3.46Å; S402-C404 PolarHBondContact OG-N 3.31Å; S402-C404 VanDerWaalsContact OG-N 3.13Å; C404-E406 VanDerWaalsContact C-N 3.32Å; C404-E406 PolarHBondContact O-N 3.38Å; C404-L407 PolarHBondContact O-N 3.45Å; C404-L407 VanDerWaalsContact O-N 3.17Å; C404-L408 VanDerWaalsContact O-CG 3.28Å; C404-L408 WeakPolarHBondContact O-CG 3.5Å; C404-L408 PolarHBondContact O-N 3.03Å
405P91.6Very high80.3Confident2 Ų235.8 Ų35.81%0.01320%0.196CC..Hα-helixtrans-59.8-38.6-179.4-14.925.2000113.5S402 A409 V444 V449 F450S402-P405 WeakPolarHBondContact O-CD 3.49Å; P405-A409 WeakPolarHBondContact O-CB 3.4Å; P405-A409 PolarHBondContact O-N 3.08Å; P405-A409 VanDerWaalsContact O-N 3.13Å; P405-V444 HydrophobicContact CB-CG1 4.14Å; P405-V444 HydrophobicContact CG-CG1 3.66Å; P405-V449 HydrophobicContact CB-CB 3.88Å; P405-V449 HydrophobicContact CB-CG1 3.99Å; P405-V449 HydrophobicContact CG-CB 4.23Å; P405-V449 HydrophobicContact CG-CG1 4.42Å; P405-F450 HydrophobicContact CB-CB 3.88Å; P405-F450 WeakPolarHBondContact O-CD2 3.5Å
406E88.2Confident83Confident29 Ų2931.9 Ų31.914%0.13616%0.155CC..Hα-helixtrans-67.3-45.7176.3-178.2-164.4144.900110.7K403 C404 L408 A409 N410 Y453K403-E406 VanDerWaalsContact CE-OE1 3.24Å; K403-E406 WeakPolarHBondContact CE-OE1 3.22Å; K403-E406 WeakPolarHBondContact CE-OE2 3.3Å; K403-E406 HydrophobicContact CG-CB 4.22Å; K403-E406 WeakPolarHBondContact CG-OE2 3.46Å; K403-E406 IonicContact NZ-OE1 2.73Å; K403-E406 PolarHBondContact O-N 3.05Å; K403-E406 VanDerWaalsContact O-N 3.11Å; C404-E406 VanDerWaalsContact C-N 3.32Å; C404-E406 PolarHBondContact O-N 3.38Å; E406-L408 PolarHBondContact O-N 3.02Å; E406-A409 PolarHBondContact O-N 3.42Å; E406-N410 WeakPolarHBondContact O-CB 3.16Å; E406-N410 PolarHBondContact O-N 3.37Å; E406-N410 PolarHBondContact O-ND2 2.91Å; E406-Y453 HydrophobicContact CB-CD2 3.86Å; E406-Y453 HydrophobicContact CB-CE2 3.76Å; E406-Y453 HydrophobicContact CB-CG 4.49Å; E406-Y453 HydrophobicContact CG-CD1 4.15Å; E406-Y453 HydrophobicContact CG-CD2 3.87Å; E406-Y453 HydrophobicContact CG-CE1 4Å; E406-Y453 HydrophobicContact CG-CE2 3.69Å; E406-Y453 HydrophobicContact CG-CG 4.1Å
407L89.7Confident85.1Confident8 Ų832.1 Ų32.14%0.04215%0.153CC..Hα-helixtrans-64.1-40.3-179.3-65.4174000111.8Y340 K403 C404 N410 Y411Y340-L407 HydrophobicContact CD1-CB 3.79Å; Y340-L407 HydrophobicContact CD1-CD1 3.58Å; Y340-L407 HydrophobicContact CD1-CG 4.32Å; Y340-L407 HydrophobicContact CD2-CD1 3.78Å; Y340-L407 HydrophobicContact CE1-CB 4.06Å; Y340-L407 HydrophobicContact CE1-CD1 3.64Å; Y340-L407 HydrophobicContact CE1-CG 4.5Å; Y340-L407 HydrophobicContact CE2-CD1 3.88Å; Y340-L407 HydrophobicContact CG-CB 4.47Å; Y340-L407 HydrophobicContact CG-CD1 3.65Å; K403-L407 HydrophobicContact CG-CG 4.45Å; K403-L407 PolarHBondContact O-N 3.47Å; K403-L407 VanDerWaalsContact O-N 3.15Å; C404-L407 PolarHBondContact O-N 3.45Å; C404-L407 VanDerWaalsContact O-N 3.17Å; L407-N410 PolarHBondContact O-N 3.31Å; L407-Y411 PolarHBondContact O-N 3.03Å
408L94.3Very high86.8Confident0 Ų028 Ų280%014%0.135CC..Hα-helixtrans-60.9-46.2172.6-66.3170.9000111.1V341 C404 E406 N410 Y411 C412 V437 V440 L441 V444 F450V341-L408 HydrophobicContact CG1-CD2 4.22Å; V341-L408 HydrophobicContact CG2-CD2 3.65Å; C404-L408 VanDerWaalsContact O-CG 3.28Å; C404-L408 WeakPolarHBondContact O-CG 3.5Å; C404-L408 PolarHBondContact O-N 3.03Å; E406-L408 PolarHBondContact O-N 3.02Å; L408-N410 VanDerWaalsContact C-N 3.34Å; L408-N410 PolarHBondContact O-N 3.05Å; L408-Y411 PolarHBondContact O-N 3.3Å; L408-C412 PolarHBondContact O-N 3.16Å; L408-C412 PolarHBondContact O-SG 2.86Å; L408-V437 HydrophobicContact CB-CG1 3.99Å; L408-V437 HydrophobicContact CD2-CG1 3.68Å; L408-V437 HydrophobicContact CG-CG1 4.37Å; L408-V440 HydrophobicContact CD1-CG1 4.19Å; L408-V440 HydrophobicContact CD2-CB 4.06Å; L408-V440 HydrophobicContact CD2-CG1 3.96Å; L408-L441 HydrophobicContact CD1-CB 4.46Å; L408-L441 HydrophobicContact CD1-CD1 4.3Å; L408-V444 HydrophobicContact CD1-CG2 3.65Å; L408-F450 HydrophobicContact CB-CD2 3.96Å; L408-F450 HydrophobicContact CB-CE2 4.07Å
409A93.3Very high87.9Confident0 Ų027.6 Ų27.60%013%0.132CC..Hα-helixtrans-63.6-38.3178.300000112.5P405 E406 D413 F450 H454P405-A409 WeakPolarHBondContact O-CB 3.4Å; P405-A409 PolarHBondContact O-N 3.08Å; P405-A409 VanDerWaalsContact O-N 3.13Å; E406-A409 PolarHBondContact O-N 3.42Å; A409-D413 PolarHBondContact O-N 3.48Å; A409-F450 HydrophobicContact CB-CD2 3.82Å; A409-F450 HydrophobicContact CB-CE2 4.01Å; A409-H454 HydrophobicContact CB-CB 4.41Å
410N90.6Very high88.9Confident36 Ų3626.3 Ų26.319%0.19314%0.135CC..Hα-helixtrans-66.4-40.5175.7-70.5-21.9000112.1E406 L407 L408 D413 M414 H457E406-N410 WeakPolarHBondContact O-CB 3.16Å; E406-N410 PolarHBondContact O-N 3.37Å; E406-N410 PolarHBondContact O-ND2 2.91Å; L407-N410 PolarHBondContact O-N 3.31Å; L408-N410 VanDerWaalsContact C-N 3.34Å; L408-N410 PolarHBondContact O-N 3.05Å; N410-D413 PolarHBondContact O-N 3.39Å; N410-M414 WeakPolarHBondContact O-CG 3.35Å; N410-M414 PolarHBondContact O-N 3.09Å; N410-H457 PolarHBondContact OD1-NE2 2.72Å
411Y93.7Very high89.6Confident4 Ų425.9 Ų25.92%0.01613%0.131CC..Hα-helixtrans-67-42.8176.6-173.4-133.3000111.6E338 V341 L407 L408 D413 M414 L415 L421 K433 V437E338-Y411 HydrophobicContact CB-CD2 3.73Å; E338-Y411 HydrophobicContact CB-CE2 3.4Å; E338-Y411 HydrophobicContact CG-CD2 4.31Å; E338-Y411 HydrophobicContact CG-CE2 3.48Å; E338-Y411 VanDerWaalsContact CG-CE2 3.48Å; E338-Y411 PolarHBondContact OE1-OH 3.47Å; V341-Y411 HydrophobicContact CB-CD1 3.93Å; V341-Y411 HydrophobicContact CB-CE1 4.32Å; V341-Y411 HydrophobicContact CG1-CD1 4.01Å; V341-Y411 HydrophobicContact CG1-CE1 4.24Å; V341-Y411 HydrophobicContact CG2-CD1 3.97Å; V341-Y411 HydrophobicContact CG2-CG 4.33Å; L407-Y411 PolarHBondContact O-N 3.03Å; L408-Y411 PolarHBondContact O-N 3.3Å; Y411-D413 VanDerWaalsContact C-N 3.3Å; Y411-D413 PolarHBondContact O-N 3.11Å; Y411-M414 WeakPolarHBondContact O-CB 3.22Å; Y411-M414 PolarHBondContact O-N 2.92Å; Y411-M414 VanDerWaalsContact O-N 3.11Å; Y411-L415 HydrophobicContact CD1-CD1 4.26Å; Y411-L415 HydrophobicContact CE1-CD1 3.93Å; Y411-L415 HydrophobicContact CE2-CD1 4.34Å; Y411-L415 HydrophobicContact CE2-CD2 4.3Å; Y411-L415 HydrophobicContact CE2-CG 4.21Å; Y411-L415 PolarHBondContact O-N 2.75Å; Y411-L415 VanDerWaalsContact O-N 3.14Å; Y411-L421 HydrophobicContact CE2-CD2 4.31Å; Y411-K433 PolarHBondContact OH-NZ 3.42Å; Y411-V437 HydrophobicContact CD1-CG2 3.53Å; Y411-V437 HydrophobicContact CE1-CG2 3.9Å
412C95Very high89.9Confident0 Ų025.6 Ų25.60%013%0.13CC..Hα-helixtrans-54.9-44.3169.8-720000112L408 M414 L415 L416 L434L408-C412 PolarHBondContact O-N 3.16Å; L408-C412 PolarHBondContact O-SG 2.86Å; C412-M414 VanDerWaalsContact C-N 3.32Å; C412-M414 PolarHBondContact O-N 2.73Å; C412-L415 PolarHBondContact O-N 3.4Å; C412-L416 HydrophobicContact CB-CD1 4.48Å; C412-L416 WeakPolarHBondContact O-CB 3.01Å; C412-L416 VanDerWaalsContact O-CG 3.32Å; C412-L416 WeakPolarHBondContact O-CG 3.35Å; C412-L416 PolarHBondContact O-N 2.89Å; C412-L434 HydrophobicContact CB-CD2 4.18Å
413D92.6Very high90.3Very high6 Ų633.1 Ų33.13%0.03216%0.162CC..Hα-helixtrans-61.5-38.3176.7178.764.7000112.7A409 N410 Y411 L415 R417 H457 R461A409-D413 PolarHBondContact O-N 3.48Å; N410-D413 PolarHBondContact O-N 3.39Å; Y411-D413 VanDerWaalsContact C-N 3.3Å; Y411-D413 PolarHBondContact O-N 3.11Å; D413-L415 VanDerWaalsContact C-N 3.33Å; D413-L415 PolarHBondContact O-N 3.07Å; D413-R417 WeakPolarHBondContact O-CB 3.3Å; D413-R417 PolarHBondContact O-N 3.02Å; D413-R417 IonicContact OD2-CZ 3.32Å; D413-R417 IonicContact OD2-NE 3.91Å; D413-R417 IonicContact OD2-NH1 2.76Å; D413-R417 PolarHBondContact OD2-NH1 2.7Å; D413-R417 IonicContact OD2-NH2 3.16Å; D413-R417 PolarHBondContact OD2-NH2 3.2Å; D413-H457 HydrophobicContact CB-CB 3.92Å; D413-H457 IonicContact OD1-CG 3Å; D413-R461 IonicContact OD1-CZ 3.7Å; D413-R461 IonicContact OD1-NH1 2.94Å; D413-R461 PolarHBondContact OD1-NH1 3.24Å
414M91.4Very high90.6Very high52 Ų5238.3 Ų38.326%0.25618%0.184SC..Hα-helixtrans-64.5-38177.7-73.6176.454.100112.9N410 Y411 C412 T419 L421N410-M414 WeakPolarHBondContact O-CG 3.35Å; N410-M414 PolarHBondContact O-N 3.09Å; Y411-M414 WeakPolarHBondContact O-CB 3.22Å; Y411-M414 PolarHBondContact O-N 2.92Å; Y411-M414 VanDerWaalsContact O-N 3.11Å; C412-M414 VanDerWaalsContact C-N 3.32Å; C412-M414 PolarHBondContact O-N 2.73Å; M414-T419 PolarHBondContact O-OG1 3.41Å; M414-L421 HydrophobicContact CB-CD2 4.5Å; M414-L421 HydrophobicContact CE-CD2 4.14Å
415L94.2Very high90.7Very high0 Ų040.1 Ų40.10%019%0.194CC..Hα-helixtrans-73.6-43.7177.3-65.8173000111.9Y411 C412 D413 L421 S422 L425 I430 K433 L434Y411-L415 HydrophobicContact CD1-CD1 4.26Å; Y411-L415 HydrophobicContact CE1-CD1 3.93Å; Y411-L415 HydrophobicContact CE2-CD1 4.34Å; Y411-L415 HydrophobicContact CE2-CD2 4.3Å; Y411-L415 HydrophobicContact CE2-CG 4.21Å; Y411-L415 PolarHBondContact O-N 2.75Å; Y411-L415 VanDerWaalsContact O-N 3.14Å; C412-L415 PolarHBondContact O-N 3.4Å; D413-L415 VanDerWaalsContact C-N 3.33Å; D413-L415 PolarHBondContact O-N 3.07Å; L415-L421 HydrophobicContact CD2-CD2 4.1Å; L415-S422 VanDerWaalsContact O-CB 3.29Å; L415-S422 WeakPolarHBondContact O-CB 3.44Å; L415-L425 HydrophobicContact CD2-CD1 3.92Å; L415-I430 HydrophobicContact CB-CG2 4.35Å; L415-K433 HydrophobicContact CD1-CB 3.88Å; L415-K433 HydrophobicContact CD2-CD 4.12Å; L415-L434 HydrophobicContact CB-CD2 4.32Å; L415-L434 HydrophobicContact CD1-CD2 3.96Å; L415-L434 HydrophobicContact CD1-CG 4.2Å
416L95.3Very high90.8Very high3 Ų343.6 Ų43.62%0.01622%0.215CC..Hα-helixtrans-81.9-16.9-175.4-68.5169.8000114.1C412 L434 S467 A468 I472 E473 M476C412-L416 HydrophobicContact CB-CD1 4.48Å; C412-L416 WeakPolarHBondContact O-CB 3.01Å; C412-L416 VanDerWaalsContact O-CG 3.32Å; C412-L416 WeakPolarHBondContact O-CG 3.35Å; C412-L416 PolarHBondContact O-N 2.89Å; L416-L434 HydrophobicContact CD1-CD2 4.44Å; L416-L434 HydrophobicContact CD2-CD1 3.69Å; L416-L434 HydrophobicContact CG-CD1 4.22Å; L416-L434 HydrophobicContact CG-CD2 4.29Å; L416-S467 CarbonylContact O-C 3.42Å; L416-S467 WeakPolarHBondContact O-CA 3.46Å; L416-A468 PolarHBondContact O-N 2.86Å; L416-I472 HydrophobicContact CD2-CG2 3.73Å; L416-E473 HydrophobicContact CD2-CG 4.44Å; L416-M476 HydrophobicContact CD1-CG 4.28Å
417R91.7Very high91.1Very high48 Ų4845 Ų4518%0.18123%0.228CC..BIsolated β-bridgetrans-92.9147.7175.3-178.7175.962.5-143-9.6110.6D413 T419 S422 R461 I466D413-R417 WeakPolarHBondContact O-CB 3.3Å; D413-R417 PolarHBondContact O-N 3.02Å; D413-R417 IonicContact OD2-CZ 3.32Å; D413-R417 IonicContact OD2-NE 3.91Å; D413-R417 IonicContact OD2-NH1 2.76Å; D413-R417 PolarHBondContact OD2-NH1 2.7Å; D413-R417 IonicContact OD2-NH2 3.16Å; D413-R417 PolarHBondContact OD2-NH2 3.2Å; R417-T419 VanDerWaalsContact C-N 3.33Å; R417-T419 HydrophobicContact CB-CG2 4.06Å; R417-T419 HydrophobicContact CG-CG2 4.14Å; R417-T419 WeakPolarHBondContact O-CG2 3.27Å; R417-T419 PolarHBondContact O-N 3.19Å; R417-S422 WeakPolarHBondContact O-CB 3.49Å; R417-S422 PolarHBondContact O-OG 3.21Å; R417-R461 HydrophobicContact CB-CG 4.39Å; R417-I466 CarbonylContact C-O 3.58Å; R417-I466 WeakPolarHBondContact CA-O 3.43Å; R417-I466 HydrophobicContact CG-CB 4.38Å; R417-I466 HydrophobicContact CG-CD1 3.98Å; R417-I466 HydrophobicContact CG-CG1 4.16Å
418K87.5Confident91.3Very high111 Ų11152.3 Ų52.348%0.48326%0.262SS..SBendtrans-56.488.3166.3-66.5175.5-170.1163.80111D465 I466 S467K418-D465 PolarHBondContact NZ-O 3Å; K418-I466 WeakPolarHBondContact CG-O 3.43Å; K418-I466 PolarHBondContact N-O 3.24Å; K418-S467 WeakPolarHBondContact CE-O 3.34Å
419T82.7Confident91.4Very high17 Ų1756.7 Ų56.710%0.10428%0.282CS..  trans-120.3166.2178.865.40000110.6M414 R417 L421 S422 K423M414-T419 PolarHBondContact O-OG1 3.41Å; R417-T419 VanDerWaalsContact C-N 3.33Å; R417-T419 HydrophobicContact CB-CG2 4.06Å; R417-T419 HydrophobicContact CG-CG2 4.14Å; R417-T419 WeakPolarHBondContact O-CG2 3.27Å; R417-T419 PolarHBondContact O-N 3.19Å; T419-L421 PolarHBondContact O-N 3.38Å; T419-L421 PolarHBondContact OG1-N 3.06Å; T419-S422 PolarHBondContact N-OG 3.02Å; T419-S422 PolarHBondContact O-N 3.23Å; T419-S422 PolarHBondContact O-OG 3.42Å; T419-S422 PolarHBondContact OG1-N 3.21Å; T419-K423 WeakPolarHBondContact O-CB 3.34Å; T419-K423 VanDerWaalsContact O-CG 3.25Å; T419-K423 WeakPolarHBondContact O-CG 3.37Å; T419-K423 PolarHBondContact O-N 3.07Å
420P84.8Confident91.5Very high104 Ų10457 Ų5768%0.67528%0.284SS*.THydrogen-bonded Turntrans-58.8-25170-24.535.2000113.7K424P420-K424 WeakPolarHBondContact O-CD 3.49Å; P420-K424 VanDerWaalsContact O-CG 3.31Å; P420-K424 WeakPolarHBondContact O-CG 3.22Å
421L85.6Confident91.7Very high35 Ų3558.1 Ų58.118%0.18329%0.288CS..THydrogen-bonded Turntrans-74.3-54.8175.4177.763.9000110.5Y411 M414 L415 T419 K423 K424 L425Y411-L421 HydrophobicContact CE2-CD2 4.31Å; M414-L421 HydrophobicContact CB-CD2 4.5Å; M414-L421 HydrophobicContact CE-CD2 4.14Å; L415-L421 HydrophobicContact CD2-CD2 4.1Å; T419-L421 PolarHBondContact O-N 3.38Å; T419-L421 PolarHBondContact OG1-N 3.06Å; L421-K423 PolarHBondContact O-N 2.97Å; L421-K424 WeakPolarHBondContact O-CB 3.23Å; L421-K424 PolarHBondContact O-N 3.39Å; L421-L425 HydrophobicContact CD1-CD1 4.23Å; L421-L425 HydrophobicContact CG-CD1 4.25Å
422S88.3Confident91.8Very high8 Ų860.4 Ų60.46%0.05631%0.308CS..G310 helixtrans-61.4-30.5-178.977.30000112.6L415 R417 T419 K424 L425L415-S422 VanDerWaalsContact O-CB 3.29Å; L415-S422 WeakPolarHBondContact O-CB 3.44Å; R417-S422 WeakPolarHBondContact O-CB 3.49Å; R417-S422 PolarHBondContact O-OG 3.21Å; T419-S422 PolarHBondContact N-OG 3.02Å; T419-S422 PolarHBondContact O-N 3.23Å; T419-S422 PolarHBondContact O-OG 3.42Å; T419-S422 PolarHBondContact OG1-N 3.21Å; S422-K424 VanDerWaalsContact C-N 3.26Å; S422-K424 PolarHBondContact O-N 2.7Å; S422-L425 PolarHBondContact O-N 3.45Å
423K89.7Confident91.8Very high167 Ų16762.4 Ų62.473%0.72632%0.316SS*.G310 helixtrans-70.9-15.8175.6-73.6-179.7-178.8-168.50114.8T419 L421T419-K423 WeakPolarHBondContact O-CB 3.34Å; T419-K423 VanDerWaalsContact O-CG 3.25Å; T419-K423 WeakPolarHBondContact O-CG 3.37Å; T419-K423 PolarHBondContact O-N 3.07Å; L421-K423 PolarHBondContact O-N 2.97Å
424K92.2Very high92Very high174 Ų17462.1 Ų62.176%0.75732%0.315SS*.G310 helixtrans-94.6-10.7178.1-72.3174.9-179-1740112.8P420 L421 S422P420-K424 WeakPolarHBondContact O-CD 3.49Å; P420-K424 VanDerWaalsContact O-CG 3.31Å; P420-K424 WeakPolarHBondContact O-CG 3.22Å; L421-K424 WeakPolarHBondContact O-CB 3.23Å; L421-K424 PolarHBondContact O-N 3.39Å; S422-K424 VanDerWaalsContact C-N 3.26Å; S422-K424 PolarHBondContact O-N 2.7Å
425L92.4Very high92.2Very high38 Ų3864.5 Ų64.520%0.19932%0.324CS..SBendtrans-108.6146.7-176.7-61.4170000109.1L415 L421 S422 E429 I430 K433L415-L425 HydrophobicContact CD2-CD1 3.92Å; L421-L425 HydrophobicContact CD1-CD1 4.23Å; L421-L425 HydrophobicContact CG-CD1 4.25Å; S422-L425 PolarHBondContact O-N 3.45Å; L425-E429 WeakPolarHBondContact CA-OE2 3.45Å; L425-E429 HydrophobicContact CB-CB 4.21Å; L425-E429 HydrophobicContact CD2-CB 4.18Å; L425-I430 HydrophobicContact CB-CD1 4.3Å; L425-I430 HydrophobicContact CB-CG1 3.77Å; L425-I430 HydrophobicContact CD1-CG1 4.22Å; L425-K433 HydrophobicContact CD1-CD 4.09Å
426T94.2Very high92.3Very high75 Ų7568.5 Ų68.546%0.4634%0.343SS..  trans-74.2160.5167.159.90000110.8E428 E429 I430T426-E428 PolarHBondContact O-N 3.19Å; T426-E429 PolarHBondContact N-OE2 3.17Å; T426-E429 PolarHBondContact O-N 3.27Å; T426-E429 VanDerWaalsContact OG1-CG 3.25Å; T426-E429 WeakPolarHBondContact OG1-CG 3.34Å; T426-E429 PolarHBondContact OG1-N 2.96Å; T426-E429 PolarHBondContact OG1-OE2 3.32Å; T426-I430 WeakPolarHBondContact O-CG1 3.47Å; T426-I430 PolarHBondContact O-N 3.23Å
427S93.4Very high92.3Very high58 Ų5868.4 Ų68.441%0.40634%0.342SS..Hα-helixtrans-55.2-38.1174.1-66.80000111.8I430 E431 D469 I472S427-I430 PolarHBondContact O-N 2.98Å; S427-E431 WeakPolarHBondContact O-CB 3.13Å; S427-E431 PolarHBondContact O-N 3.4Å; S427-D469 PolarHBondContact OG-OD2 3.36Å; S427-I472 WeakPolarHBondContact O-CD1 3.46Å
428E94.7Very high92.5Very high163 Ų16366.4 Ų66.476%0.76234%0.335SS*.Hα-helixtrans-65.7-42.6176.6-65.1177.9-17300112.9T426 E431 A432T426-E428 PolarHBondContact O-N 3.19Å; E428-E431 PolarHBondContact O-N 3.36Å; E428-A432 WeakPolarHBondContact O-CB 3.5Å; E428-A432 PolarHBondContact O-N 2.97Å
429E95.7Very high92.8Very high91 Ų9163.5 Ų63.543%0.42532%0.324SS..Hα-helixtrans-67.3-36.8176.3-72.8167.1137.100112.1L425 T426 A432 K433L425-E429 WeakPolarHBondContact CA-OE2 3.45Å; L425-E429 HydrophobicContact CB-CB 4.21Å; L425-E429 HydrophobicContact CD2-CB 4.18Å; T426-E429 PolarHBondContact N-OE2 3.17Å; T426-E429 PolarHBondContact O-N 3.27Å; T426-E429 VanDerWaalsContact OG1-CG 3.25Å; T426-E429 WeakPolarHBondContact OG1-CG 3.34Å; T426-E429 PolarHBondContact OG1-N 2.96Å; T426-E429 PolarHBondContact OG1-OE2 3.32Å; E429-A432 PolarHBondContact O-N 3.43Å; E429-K433 PolarHBondContact O-N 2.93Å
430I95Very high93.4Very high8 Ų862.7 Ų62.74%0.04132%0.319CS..Hα-helixtrans-63-47.8174-69.5171.8000109.8L415 L425 T426 S427 A432 K433 L434 I472L415-I430 HydrophobicContact CB-CG2 4.35Å; L425-I430 HydrophobicContact CB-CD1 4.3Å; L425-I430 HydrophobicContact CB-CG1 3.77Å; L425-I430 HydrophobicContact CD1-CG1 4.22Å; T426-I430 WeakPolarHBondContact O-CG1 3.47Å; T426-I430 PolarHBondContact O-N 3.23Å; S427-I430 PolarHBondContact O-N 2.98Å; I430-A432 PolarHBondContact O-N 2.96Å; I430-K433 PolarHBondContact O-N 2.8Å; I430-L434 HydrophobicContact CG2-CD1 3.84Å; I430-L434 HydrophobicContact CG2-CG 4.38Å; I430-L434 WeakPolarHBondContact O-CB 3.33Å; I430-L434 VanDerWaalsContact O-CG 3.28Å; I430-L434 WeakPolarHBondContact O-CG 3.38Å; I430-L434 PolarHBondContact O-N 3.31Å; I430-I472 HydrophobicContact CB-CD1 4.22Å; I430-I472 HydrophobicContact CG2-CD1 4.03Å; I430-I472 HydrophobicContact CG2-CG2 4.31Å
431E95.9Very high93.9Very high59 Ų5957.8 Ų57.828%0.27629%0.287SS..Hα-helixtrans-58.4-46.7176.2169.7170.4163.600112S427 E428 K433 L434 K435 W479S427-E431 WeakPolarHBondContact O-CB 3.13Å; S427-E431 PolarHBondContact O-N 3.4Å; E428-E431 PolarHBondContact O-N 3.36Å; E431-K433 PolarHBondContact O-N 3.49Å; E431-L434 PolarHBondContact O-N 3.47Å; E431-K435 HydrophobicContact CG-CD 4.17Å; E431-K435 WeakPolarHBondContact O-CG 3.49Å; E431-K435 PolarHBondContact O-N 3.47Å; E431-K435 WeakPolarHBondContact OE1-CE 3.42Å; E431-K435 IonicContact OE1-NZ 2.7Å; E431-K435 PolarHBondContact OE1-NZ 2.71Å; E431-W479 HydrophobicContact CB-CH2 4.07Å; E431-W479 HydrophobicContact CG-CH2 3.51Å; E431-W479 HydrophobicContact CG-CZ2 3.86Å; E431-W479 HydrophobicContact CG-CZ3 4.43Å
432A95.8Very high94.3Very high51 Ų5161.7 Ų61.742%0.42130%0.303SS..Hα-helixtrans-58.9-48.5178.400000111.7E428 E429 I430 L434 K435 E436E428-A432 WeakPolarHBondContact O-CB 3.5Å; E428-A432 PolarHBondContact O-N 2.97Å; E429-A432 PolarHBondContact O-N 3.43Å; I430-A432 PolarHBondContact O-N 2.96Å; A432-L434 PolarHBondContact O-N 2.87Å; A432-K435 PolarHBondContact O-N 2.94Å; A432-E436 WeakPolarHBondContact O-CG 3.3Å; A432-E436 PolarHBondContact O-N 2.78Å; A432-E436 VanDerWaalsContact O-N 3.09Å
433K95.1Very high94.5Very high42 Ų4262.7 Ų62.718%0.18331%0.306CS..Hα-helixtrans-61.6-41.9176.4-77.7179.9168.8-73.80111.9E342 Y411 L415 L425 E429 I430 E431 K435 E436 V437E342-K433 IonicContact OE1-NZ 3.6Å; Y411-K433 PolarHBondContact OH-NZ 3.42Å; L415-K433 HydrophobicContact CD1-CB 3.88Å; L415-K433 HydrophobicContact CD2-CD 4.12Å; L425-K433 HydrophobicContact CD1-CD 4.09Å; E429-K433 PolarHBondContact O-N 2.93Å; I430-K433 PolarHBondContact O-N 2.8Å; E431-K433 PolarHBondContact O-N 3.49Å; K433-K435 VanDerWaalsContact C-N 3.34Å; K433-K435 PolarHBondContact O-N 3Å; K433-E436 WeakPolarHBondContact O-CB 3.42Å; K433-E436 PolarHBondContact O-N 3.34Å; K433-V437 WeakPolarHBondContact O-CG2 3.38Å; K433-V437 PolarHBondContact O-N 2.82Å
434L96.8Very high94.7Very high0 Ų055 Ų550%027%0.272CS..Hα-helixtrans-61.7-41.1176.6-72.7169.7000111.9C412 L415 L416 I430 E431 A432 E436 V437 L438 I472 M476 W479C412-L434 HydrophobicContact CB-CD2 4.18Å; L415-L434 HydrophobicContact CB-CD2 4.32Å; L415-L434 HydrophobicContact CD1-CD2 3.96Å; L415-L434 HydrophobicContact CD1-CG 4.2Å; L416-L434 HydrophobicContact CD1-CD2 4.44Å; L416-L434 HydrophobicContact CD2-CD1 3.69Å; L416-L434 HydrophobicContact CG-CD1 4.22Å; L416-L434 HydrophobicContact CG-CD2 4.29Å; I430-L434 HydrophobicContact CG2-CD1 3.84Å; I430-L434 HydrophobicContact CG2-CG 4.38Å; I430-L434 WeakPolarHBondContact O-CB 3.33Å; I430-L434 VanDerWaalsContact O-CG 3.28Å; I430-L434 WeakPolarHBondContact O-CG 3.38Å; I430-L434 PolarHBondContact O-N 3.31Å; E431-L434 PolarHBondContact O-N 3.47Å; A432-L434 PolarHBondContact O-N 2.87Å; L434-E436 VanDerWaalsContact C-N 3.31Å; L434-E436 PolarHBondContact O-N 3.23Å; L434-V437 WeakPolarHBondContact O-CB 3.34Å; L434-V437 PolarHBondContact O-N 3.12Å; L434-L438 WeakPolarHBondContact O-CG 3.23Å; L434-L438 PolarHBondContact O-N 3.46Å; L434-I472 HydrophobicContact CD1-CG2 3.53Å; L434-M476 HydrophobicContact CD2-SD 4.34Å; L434-W479 HydrophobicContact CB-CZ3 4.18Å; L434-W479 HydrophobicContact CD1-CZ3 4.13Å
435K96.2Very high94.5Very high103 Ų10349.6 Ų49.645%0.44825%0.25SC..Hα-helixtrans-62.4-36.3174.9-75.4174.4171.31710112.5E431 A432 K433 L438 L439E431-K435 HydrophobicContact CG-CD 4.17Å; E431-K435 WeakPolarHBondContact O-CG 3.49Å; E431-K435 PolarHBondContact O-N 3.47Å; E431-K435 WeakPolarHBondContact OE1-CE 3.42Å; E431-K435 IonicContact OE1-NZ 2.7Å; E431-K435 PolarHBondContact OE1-NZ 2.71Å; A432-K435 PolarHBondContact O-N 2.94Å; K433-K435 VanDerWaalsContact C-N 3.34Å; K433-K435 PolarHBondContact O-N 3Å; K435-L438 PolarHBondContact O-N 2.66Å; K435-L439 PolarHBondContact O-N 3.02Å
436E95.3Very high94.4Very high84 Ų8448.6 Ų48.639%0.39325%0.245SC..Hα-helixtrans-65.1-42.2171.9-67.5178.3157.200112.1L345 A432 K433 L434 L438 L439 V440L345-E436 HydrophobicContact CD1-CB 3.72Å; L345-E436 HydrophobicContact CD1-CG 4.45Å; L345-E436 HydrophobicContact CD2-CB 3.85Å; L345-E436 HydrophobicContact CG-CB 4.45Å; A432-E436 WeakPolarHBondContact O-CG 3.3Å; A432-E436 PolarHBondContact O-N 2.78Å; A432-E436 VanDerWaalsContact O-N 3.09Å; K433-E436 WeakPolarHBondContact O-CB 3.42Å; K433-E436 PolarHBondContact O-N 3.34Å; L434-E436 VanDerWaalsContact C-N 3.31Å; L434-E436 PolarHBondContact O-N 3.23Å; E436-L438 VanDerWaalsContact C-N 3.27Å; E436-L438 PolarHBondContact O-N 2.75Å; E436-L439 WeakPolarHBondContact O-CB 3.46Å; E436-L439 PolarHBondContact O-N 2.92Å; E436-L439 VanDerWaalsContact O-N 3.17Å; E436-V440 PolarHBondContact O-N 3.37Å
437V95.7Very high94.3Very high0 Ų045.8 Ų45.80%023%0.226CC..Hα-helixtrans-58.7-42.8173.1-175.40000110.8V341 L408 Y411 K433 L434 L439 V440 L441V341-V437 HydrophobicContact CG1-CG2 4.24Å; L408-V437 HydrophobicContact CB-CG1 3.99Å; L408-V437 HydrophobicContact CD2-CG1 3.68Å; L408-V437 HydrophobicContact CG-CG1 4.37Å; Y411-V437 HydrophobicContact CD1-CG2 3.53Å; Y411-V437 HydrophobicContact CE1-CG2 3.9Å; K433-V437 WeakPolarHBondContact O-CG2 3.38Å; K433-V437 PolarHBondContact O-N 2.82Å; L434-V437 WeakPolarHBondContact O-CB 3.34Å; L434-V437 PolarHBondContact O-N 3.12Å; V437-L439 VanDerWaalsContact C-N 3.31Å; V437-L439 PolarHBondContact O-N 3.16Å; V437-V440 PolarHBondContact O-N 3.02Å; V437-L441 PolarHBondContact O-N 3.46Å
438L95.6Very high94.2Very high7 Ų743.4 Ų43.44%0.03721%0.209CC..Hα-helixtrans-65.6-31.2178.7-70.5-179.6000113L434 K435 E436 L441 K442 M476 W479 L480 V483L434-L438 WeakPolarHBondContact O-CG 3.23Å; L434-L438 PolarHBondContact O-N 3.46Å; K435-L438 PolarHBondContact O-N 2.66Å; E436-L438 VanDerWaalsContact C-N 3.27Å; E436-L438 PolarHBondContact O-N 2.75Å; L438-L441 HydrophobicContact CD2-CD2 3.83Å; L438-L441 PolarHBondContact O-N 3.41Å; L438-K442 PolarHBondContact O-N 3.46Å; L438-M476 HydrophobicContact CD1-SD 4.45Å; L438-M476 HydrophobicContact CD2-CE 3.84Å; L438-M476 HydrophobicContact CG-CE 4.43Å; L438-W479 HydrophobicContact CD1-CB 3.41Å; L438-W479 VanDerWaalsContact CD1-CB 3.41Å; L438-W479 HydrophobicContact CD1-CD2 4.48Å; L438-W479 HydrophobicContact CD1-CE3 4.24Å; L438-W479 HydrophobicContact CD1-CG 4.21Å; L438-L480 HydrophobicContact CD2-CD2 3.83Å; L438-V483 HydrophobicContact CB-CG2 4.01Å; L438-V483 HydrophobicContact CD1-CG2 4.42Å; L438-V483 HydrophobicContact CD2-CG2 4.27Å; L438-V483 HydrophobicContact CG-CG2 4.47Å
439L94.3Very high94Very high50 Ų5035.7 Ų35.726%0.26217%0.173SC..Hα-helixtrans-60.6-47.6170.5174.866.3000111F348 K435 E436 V437 L441 K442 Y443F348-L439 HydrophobicContact CD1-CD2 3.86Å; F348-L439 HydrophobicContact CE1-CD2 3.73Å; F348-L439 HydrophobicContact CZ-CD1 4.32Å; F348-L439 HydrophobicContact CZ-CD2 4.31Å; K435-L439 PolarHBondContact O-N 3.02Å; E436-L439 WeakPolarHBondContact O-CB 3.46Å; E436-L439 PolarHBondContact O-N 2.92Å; E436-L439 VanDerWaalsContact O-N 3.17Å; V437-L439 VanDerWaalsContact C-N 3.31Å; V437-L439 PolarHBondContact O-N 3.16Å; L439-L441 VanDerWaalsContact C-N 3.33Å; L439-L441 PolarHBondContact O-N 3.08Å; L439-K442 WeakPolarHBondContact O-CB 3.33Å; L439-K442 PolarHBondContact O-N 2.9Å; L439-Y443 HydrophobicContact CD1-CE2 4.23Å; L439-Y443 VanDerWaalsContact O-CD2 3.23Å; L439-Y443 WeakPolarHBondContact O-CD2 3.41Å; L439-Y443 WeakPolarHBondContact O-CE2 3.24Å
440V95.2Very high93.9Very high0 Ų031.3 Ų31.30%015%0.153CC..Hα-helixtrans-64.2-40.7176.8-175.70000110.7L344 L345 V377 L408 E436 V437 K442 Y443L344-V440 HydrophobicContact CD1-CG1 3.96Å; L345-V440 HydrophobicContact CD2-CG2 3.67Å; L345-V440 HydrophobicContact CG-CG2 4.11Å; V377-V440 HydrophobicContact CG1-CG1 4.41Å; V377-V440 HydrophobicContact CG2-CG1 4.29Å; L408-V440 HydrophobicContact CD1-CG1 4.19Å; L408-V440 HydrophobicContact CD2-CB 4.06Å; L408-V440 HydrophobicContact CD2-CG1 3.96Å; E436-V440 PolarHBondContact O-N 3.37Å; V437-V440 PolarHBondContact O-N 3.02Å; V440-K442 PolarHBondContact O-N 3.07Å; V440-K442 VanDerWaalsContact O-N 3.17Å; V440-Y443 PolarHBondContact O-N 3.46Å
441L94.8Very high93.8Very high0 Ų031.3 Ų31.30%015%0.152CC..Hα-helixtrans-58.9-28.2179.1-174.761.8000113.2L408 V437 L438 L439 Y443 V444 K447 F450 L480 V483 M485L408-L441 HydrophobicContact CD1-CB 4.46Å; L408-L441 HydrophobicContact CD1-CD1 4.3Å; V437-L441 PolarHBondContact O-N 3.46Å; L438-L441 HydrophobicContact CD2-CD2 3.83Å; L438-L441 PolarHBondContact O-N 3.41Å; L439-L441 VanDerWaalsContact C-N 3.33Å; L439-L441 PolarHBondContact O-N 3.08Å; L441-Y443 PolarHBondContact O-N 3.38Å; L441-V444 HydrophobicContact CD1-CB 4.19Å; L441-V444 HydrophobicContact CD1-CG2 4.25Å; L441-V444 WeakPolarHBondContact O-CB 3.4Å; L441-V444 PolarHBondContact O-N 2.93Å; L441-K447 WeakPolarHBondContact O-CE 3.38Å; L441-F450 HydrophobicContact CD1-CB 3.97Å; L441-F450 HydrophobicContact CD1-CD1 4.06Å; L441-F450 HydrophobicContact CD1-CD2 3.86Å; L441-F450 HydrophobicContact CD1-CE2 4.39Å; L441-F450 HydrophobicContact CD1-CG 3.68Å; L441-F450 HydrophobicContact CD2-CD1 3.91Å; L441-F450 HydrophobicContact CD2-CD2 4.4Å; L441-F450 HydrophobicContact CD2-CE1 3.71Å; L441-F450 HydrophobicContact CD2-CE2 4.19Å; L441-F450 HydrophobicContact CD2-CG 4.27Å; L441-F450 HydrophobicContact CD2-CZ 3.85Å; L441-L480 HydrophobicContact CD2-CD2 3.88Å; L441-V483 HydrophobicContact CD2-CG1 4.39Å; L441-V483 HydrophobicContact CG-CG1 4.39Å; L441-M485 HydrophobicContact CD1-CE 4.28Å; L441-M485 HydrophobicContact CD2-CE 3.69Å; L441-M485 HydrophobicContact CG-CE 3.79Å
442K93.5Very high93.4Very high117 Ų11732.4 Ų32.451%0.50915%0.154SC..THydrogen-bonded Turntrans-59.4-31.3173.9-71175.7-175.8-175.30112.6L438 L439 V440 V483L438-K442 PolarHBondContact O-N 3.46Å; L439-K442 WeakPolarHBondContact O-CB 3.33Å; L439-K442 PolarHBondContact O-N 2.9Å; V440-K442 PolarHBondContact O-N 3.07Å; V440-K442 VanDerWaalsContact O-N 3.17Å; K442-V483 HydrophobicContact CG-CG1 3.8Å
443Y93.6Very high93Very high30 Ų3030.8 Ų30.812%0.11814%0.137CC..THydrogen-bonded Turntrans-90.5-7.3-178.9-57.6-80.5000113.1F348 D370 Y373 K374 N378 L439 V440 L441F348-Y443 HydrophobicContact CD2-CE2 4.38Å; F348-Y443 AromaticContact CE2-CE2 3.94Å; F348-Y443 HydrophobicContact CE2-CE2 3.94Å; F348-Y443 AromaticContact CE2-CZ 3.87Å; F348-Y443 WeakPolarHBondContact CE2-OH 3.33Å; D370-Y443 HydrophobicContact CB-CE1 3.88Å; D370-Y443 PolarHBondContact OD1-OH 2.97Å; Y373-Y443 HydrophobicContact CD1-CD1 4Å; Y373-Y443 AromaticContact CD1-CD2 3.6Å; Y373-Y443 HydrophobicContact CD1-CD2 3.6Å; Y373-Y443 HydrophobicContact CD1-CE1 4.34Å; Y373-Y443 AromaticContact CD1-CE2 3.96Å; Y373-Y443 HydrophobicContact CD1-CE2 3.96Å; Y373-Y443 AromaticContact CD1-CG 3.62Å; Y373-Y443 HydrophobicContact CD1-CG 3.62Å; Y373-Y443 AromaticContact CE1-CD2 3.56Å; Y373-Y443 HydrophobicContact CE1-CD2 3.56Å; Y373-Y443 HydrophobicContact CE1-CE2 4.03Å; Y373-Y443 AromaticContact CE1-CG 3.97Å; Y373-Y443 HydrophobicContact CE1-CG 3.97Å; K374-Y443 HydrophobicContact CB-CD1 4.3Å; K374-Y443 WeakPolarHBondContact CG-O 3.45Å; N378-Y443 PolarHBondContact ND2-O 3.35Å; L439-Y443 HydrophobicContact CD1-CE2 4.23Å; L439-Y443 VanDerWaalsContact O-CD2 3.23Å; L439-Y443 WeakPolarHBondContact O-CD2 3.41Å; L439-Y443 WeakPolarHBondContact O-CE2 3.24Å; V440-Y443 PolarHBondContact O-N 3.46Å; L441-Y443 PolarHBondContact O-N 3.38Å
444V92.8Very high92.9Very high4 Ų429 Ų292%0.02413%0.129CC..  trans-73.8131.8176.5172.90000110.8V377 P405 L408 L441 K447V377-V444 HydrophobicContact CG1-CG2 3.83Å; P405-V444 HydrophobicContact CB-CG1 4.14Å; P405-V444 HydrophobicContact CG-CG1 3.66Å; L408-V444 HydrophobicContact CD1-CG2 3.65Å; L441-V444 HydrophobicContact CD1-CB 4.19Å; L441-V444 HydrophobicContact CD1-CG2 4.25Å; L441-V444 WeakPolarHBondContact O-CB 3.4Å; L441-V444 PolarHBondContact O-N 2.93Å; V444-K447 HydrophobicContact CG1-CG 4.37Å
445Q89.8Confident92.6Very high61 Ų6130.4 Ų30.429%0.28514%0.135SC..SBendtrans-78.7-45.8177.1-71.7175.77.700112.4N378 K447 F746N378-Q445 HydrophobicContact CB-CG 4.35Å; N378-Q445 WeakPolarHBondContact OD1-CB 3.47Å; N378-Q445 PolarHBondContact OD1-N 2.92Å; Q445-K447 PolarHBondContact O-N 3.43Å; Q445-F746 WeakPolarHBondContact O-CA 3.5Å
446N89.1Confident92.1Very high17 Ų1726.9 Ų26.99%0.09113%0.126CC..  trans-99.369.2-174-65.3-18.5000110.9E401 D448 V449 L747E401-N446 PolarHBondContact OE2-ND2 3.36Å; N446-D448 PolarHBondContact O-N 3Å; N446-V449 HydrophobicContact CB-CG2 4.13Å; N446-V449 WeakPolarHBondContact O-CB 3.5Å; N446-V449 PolarHBondContact O-N 3.23Å; N446-L747 PolarHBondContact OD1-N 2.98Å; N446-L747 VanDerWaalsContact OD1-N 3.17Å
447K92.3Very high91.8Very high16 Ų1624.5 Ų24.57%0.0711%0.114CC..Hα-helixtrans-67.5-24.8-177.7-68.9170.9164.3-171.80112.5L441 V444 Q445 V449 F450 M451 V483 M485 N744 M745L441-K447 WeakPolarHBondContact O-CE 3.38Å; V444-K447 HydrophobicContact CG1-CG 4.37Å; Q445-K447 PolarHBondContact O-N 3.43Å; K447-V449 VanDerWaalsContact C-N 3.28Å; K447-V449 PolarHBondContact O-N 2.98Å; K447-F450 WeakPolarHBondContact O-CB 3.45Å; K447-F450 PolarHBondContact O-N 2.88Å; K447-M451 WeakPolarHBondContact O-CG 3.41Å; K447-M451 PolarHBondContact O-N 3.01Å; K447-V483 PolarHBondContact NZ-O 3.41Å; K447-M485 HydrophobicContact CB-CE 3.95Å; K447-M485 HydrophobicContact CB-SD 3.92Å; K447-M485 HydrophobicContact CD-CE 3.39Å; K447-M485 HydrophobicContact CD-SD 4.21Å; K447-M485 HydrophobicContact CG-CE 3.71Å; K447-M485 HydrophobicContact CG-SD 4.37Å; K447-N744 VanDerWaalsContact CD-O 3.3Å; K447-N744 WeakPolarHBondContact CD-O 3.42Å; K447-M745 PolarHBondContact N-O 2.82Å
448D91.4Very high91.7Very high8 Ų824.6 Ų24.64%0.04312%0.115CC..Hα-helixtrans-58.9-36.9173.966.1-25.6000113.3N446 M451 R452 Y489 R711 M745N446-D448 PolarHBondContact O-N 3Å; D448-M451 PolarHBondContact O-N 3.4Å; D448-R452 PolarHBondContact O-N 3.47Å; D448-Y489 HydrophobicContact CB-CE2 4.5Å; D448-R711 IonicContact OD1-CZ 3.33Å; D448-R711 IonicContact OD1-NE 2.68Å; D448-R711 IonicContact OD1-NH2 3.82Å; D448-R711 PolarHBondContact OD1-NH2 3.24Å; D448-R711 WeakPolarHBondContact OD2-CG 3.31Å; D448-R711 IonicContact OD2-CZ 3.25Å; D448-R711 IonicContact OD2-NE 2.79Å; D448-R711 PolarHBondContact OD2-NE 3.43Å; D448-R711 IonicContact OD2-NH2 3.9Å; D448-R711 PolarHBondContact OD2-NH2 3.37Å; D448-M745 PolarHBondContact N-O 3.22Å
449V90.8Very high91.4Very high1 Ų125 Ų251%0.00612%0.118CC..Hα-helixtrans-61.9-49.6173.2-178.20000110.2L385 P405 N446 K447 M451 R452 Y453 I707L385-V449 HydrophobicContact CD2-CG1 3.75Å; L385-V449 HydrophobicContact CD2-CG2 4.32Å; P405-V449 HydrophobicContact CB-CB 3.88Å; P405-V449 HydrophobicContact CB-CG1 3.99Å; P405-V449 HydrophobicContact CG-CB 4.23Å; P405-V449 HydrophobicContact CG-CG1 4.42Å; N446-V449 HydrophobicContact CB-CG2 4.13Å; N446-V449 WeakPolarHBondContact O-CB 3.5Å; N446-V449 PolarHBondContact O-N 3.23Å; K447-V449 VanDerWaalsContact C-N 3.28Å; K447-V449 PolarHBondContact O-N 2.98Å; V449-M451 VanDerWaalsContact C-N 3.33Å; V449-M451 PolarHBondContact O-N 3.08Å; V449-R452 PolarHBondContact O-N 2.74Å; V449-Y453 HydrophobicContact CG1-CD2 3.87Å; V449-Y453 HydrophobicContact CG1-CE2 3.69Å; V449-Y453 VanDerWaalsContact O-CD2 3.26Å; V449-Y453 WeakPolarHBondContact O-CD2 3.43Å; V449-Y453 PolarHBondContact O-N 2.53Å; V449-I707 HydrophobicContact CG2-CD1 4.37Å; V449-I707 HydrophobicContact CG2-CG2 4.4Å
450F93.2Very high90.9Very high0 Ų023.8 Ų23.80%011%0.11CC..Hα-helixtrans-55.7-48.7175.3171.2-86.9000110.8P405 L408 A409 L441 K447 R452 Y453 H454 M476 L480P405-F450 HydrophobicContact CB-CB 3.88Å; P405-F450 WeakPolarHBondContact O-CD2 3.5Å; L408-F450 HydrophobicContact CB-CD2 3.96Å; L408-F450 HydrophobicContact CB-CE2 4.07Å; A409-F450 HydrophobicContact CB-CD2 3.82Å; A409-F450 HydrophobicContact CB-CE2 4.01Å; L441-F450 HydrophobicContact CD1-CB 3.97Å; L441-F450 HydrophobicContact CD1-CD1 4.06Å; L441-F450 HydrophobicContact CD1-CD2 3.86Å; L441-F450 HydrophobicContact CD1-CE2 4.39Å; L441-F450 HydrophobicContact CD1-CG 3.68Å; L441-F450 HydrophobicContact CD2-CD1 3.91Å; L441-F450 HydrophobicContact CD2-CD2 4.4Å; L441-F450 HydrophobicContact CD2-CE1 3.71Å; L441-F450 HydrophobicContact CD2-CE2 4.19Å; L441-F450 HydrophobicContact CD2-CG 4.27Å; L441-F450 HydrophobicContact CD2-CZ 3.85Å; K447-F450 WeakPolarHBondContact O-CB 3.45Å; K447-F450 PolarHBondContact O-N 2.88Å; F450-R452 VanDerWaalsContact C-N 3.3Å; F450-R452 PolarHBondContact O-N 2.94Å; F450-Y453 PolarHBondContact O-N 2.92Å; F450-H454 HydrophobicContact CD1-CB 4.33Å; F450-H454 HydrophobicContact CE1-CB 3.96Å; F450-H454 HydrophobicContact CZ-CB 4.23Å; F450-H454 AromaticContact CZ-ND1 3.83Å; F450-H454 WeakPolarHBondContact O-CB 3.33Å; F450-H454 PolarHBondContact O-N 2.99Å; F450-M476 HydrophobicContact CZ-CE 4.3Å; F450-L480 HydrophobicContact CE1-CD1 4.5Å; F450-L480 HydrophobicContact CE1-CD2 3.58Å; F450-L480 HydrophobicContact CZ-CD2 4.14Å
451M92.5Very high90.7Very high7 Ų723.8 Ų23.83%0.03411%0.11CC..Hα-helixtrans-62.9-35.3-178-70.1-54.4-71.200112.6K447 D448 V449 K455 L480 M485 Y489 L493K447-M451 WeakPolarHBondContact O-CG 3.41Å; K447-M451 PolarHBondContact O-N 3.01Å; D448-M451 PolarHBondContact O-N 3.4Å; V449-M451 VanDerWaalsContact C-N 3.33Å; V449-M451 PolarHBondContact O-N 3.08Å; M451-K455 WeakPolarHBondContact O-CB 2.84Å; M451-K455 PolarHBondContact O-N 3.43Å; M451-L480 HydrophobicContact CE-CD1 4.35Å; M451-L480 HydrophobicContact SD-CD1 4.3Å; M451-L480 HydrophobicContact SD-CD2 4.43Å; M451-M485 HydrophobicContact CG-SD 3.89Å; M451-M485 HydrophobicContact SD-CB 4.48Å; M451-M485 HydrophobicContact SD-CG 3.94Å; M451-M485 HydrophobicContact SD-SD 3.8Å; M451-Y489 HydrophobicContact CB-CD2 4.16Å; M451-Y489 HydrophobicContact CB-CE2 4.49Å; M451-Y489 HydrophobicContact CB-CG 4.38Å; M451-Y489 HydrophobicContact CE-CG 4.4Å; M451-Y489 HydrophobicContact CG-CD2 3.92Å; M451-Y489 HydrophobicContact CG-CE2 4.5Å; M451-Y489 HydrophobicContact CG-CG 4.37Å; M451-L493 HydrophobicContact CE-CD1 3.75Å; M451-L493 HydrophobicContact CE-CG 4.46Å
452R87.9Confident90.6Very high82 Ų8224.4 Ų24.431%0.30911%0.113SC..Hα-helixtrans-63.7-53.2176.1-177.367.2178.1-170.92.3111.3D448 V449 F450 K455 A456 I707D448-R452 PolarHBondContact O-N 3.47Å; V449-R452 PolarHBondContact O-N 2.74Å; F450-R452 VanDerWaalsContact C-N 3.3Å; F450-R452 PolarHBondContact O-N 2.94Å; R452-K455 PolarHBondContact O-N 3.02Å; R452-A456 PolarHBondContact O-N 2.79Å; R452-I707 HydrophobicContact CB-CD1 4.11Å; R452-I707 HydrophobicContact CB-CG1 4.15Å; R452-I707 HydrophobicContact CG-CD1 4.04Å; R452-I707 HydrophobicContact CG-CG1 4.01Å
453Y88.1Confident90.4Very high17 Ų1719.9 Ų19.97%0.0679%0.094CC..Hα-helixtrans-65.1-43.7178.9-75.4-71.3000111.9E406 V449 F450 K455 A456 H457E406-Y453 HydrophobicContact CB-CD2 3.86Å; E406-Y453 HydrophobicContact CB-CE2 3.76Å; E406-Y453 HydrophobicContact CB-CG 4.49Å; E406-Y453 HydrophobicContact CG-CD1 4.15Å; E406-Y453 HydrophobicContact CG-CD2 3.87Å; E406-Y453 HydrophobicContact CG-CE1 4Å; E406-Y453 HydrophobicContact CG-CE2 3.69Å; E406-Y453 HydrophobicContact CG-CG 4.1Å; V449-Y453 HydrophobicContact CG1-CD2 3.87Å; V449-Y453 HydrophobicContact CG1-CE2 3.69Å; V449-Y453 VanDerWaalsContact O-CD2 3.26Å; V449-Y453 WeakPolarHBondContact O-CD2 3.43Å; V449-Y453 PolarHBondContact O-N 2.53Å; F450-Y453 PolarHBondContact O-N 2.92Å; Y453-K455 VanDerWaalsContact C-N 3.31Å; Y453-K455 PolarHBondContact O-N 3.05Å; Y453-A456 PolarHBondContact O-N 3.2Å; Y453-H457 PolarHBondContact O-CD2 3.43Å; Y453-H457 PolarHBondContact O-N 3.46Å
454H92.3Very high90Very high4 Ų419.5 Ų19.52%0.0199%0.094CC..Hα-helixtrans-58.7-43.7177.5-173.388.6000111.4A409 F450 H457 L458A409-H454 HydrophobicContact CB-CB 4.41Å; F450-H454 HydrophobicContact CD1-CB 4.33Å; F450-H454 HydrophobicContact CE1-CB 3.96Å; F450-H454 HydrophobicContact CZ-CB 4.23Å; F450-H454 AromaticContact CZ-ND1 3.83Å; F450-H454 WeakPolarHBondContact O-CB 3.33Å; F450-H454 PolarHBondContact O-N 2.99Å; H454-H457 PolarHBondContact O-N 3.27Å; H454-L458 WeakPolarHBondContact O-CB 3.44Å; H454-L458 PolarHBondContact O-N 3.17Å
455K91Very high89.8Confident30 Ų3024.6 Ų24.613%0.1312%0.121CC..Hα-helixtrans-63.7-41.8175.7-178.3-179.6178179.10112.7M451 R452 Y453 H457 L458 T459 L493 M496 A535M451-K455 WeakPolarHBondContact O-CB 2.84Å; M451-K455 PolarHBondContact O-N 3.43Å; R452-K455 PolarHBondContact O-N 3.02Å; Y453-K455 VanDerWaalsContact C-N 3.31Å; Y453-K455 PolarHBondContact O-N 3.05Å; K455-H457 VanDerWaalsContact C-N 3.33Å; K455-L458 PolarHBondContact O-N 3.26Å; K455-T459 WeakPolarHBondContact O-CB 3.45Å; K455-T459 PolarHBondContact O-N 3.32Å; K455-T459 PolarHBondContact O-OG1 3.38Å; K455-L493 HydrophobicContact CB-CD2 3.98Å; K455-L493 HydrophobicContact CG-CD2 3.94Å; K455-M496 HydrophobicContact CG-SD 4.2Å; K455-A535 WeakPolarHBondContact CE-O 3.42Å; K455-A535 PolarHBondContact NZ-O 3.05Å
456A85.9Confident89.8Confident30 Ų3023.4 Ų23.425%0.24812%0.117CC..Hα-helixtrans-62.7-42.8177.100000111.2R452 Y453 T459 R460R452-A456 PolarHBondContact O-N 2.79Å; Y453-A456 PolarHBondContact O-N 3.2Å; A456-T459 WeakPolarHBondContact O-CB 3.25Å; A456-T459 PolarHBondContact O-N 3.42Å; A456-R460 PolarHBondContact O-N 2.76Å; A456-R460 VanDerWaalsContact O-N 3.11Å
457H88.6Confident89.9Confident33 Ų3323 Ų2315%0.15312%0.115CC..Hα-helixtrans-65.7-44.5175.1-67.6-43.8000112.4N410 D413 Y453 H454 K455 T459 R460 R461N410-H457 PolarHBondContact OD1-NE2 2.72Å; D413-H457 HydrophobicContact CB-CB 3.92Å; D413-H457 IonicContact OD1-CG 3Å; Y453-H457 PolarHBondContact O-CD2 3.43Å; Y453-H457 PolarHBondContact O-N 3.46Å; H454-H457 PolarHBondContact O-N 3.27Å; K455-H457 VanDerWaalsContact C-N 3.33Å; H457-T459 VanDerWaalsContact C-N 3.35Å; H457-T459 PolarHBondContact O-N 2.85Å; H457-R460 WeakPolarHBondContact O-CB 3.47Å; H457-R460 PolarHBondContact O-N 3.2Å; H457-R461 WeakPolarHBondContact O-CG 2.97Å; H457-R461 PolarHBondContact O-N 3.42Å
458L92.7Very high89.9Confident2 Ų224.1 Ų24.11%0.0113%0.127CC..Hα-helixtrans-58.6-47174.6178.564.5000111.3H454 K455 R460 R461 L462 E473 L493 M496 F497H454-L458 WeakPolarHBondContact O-CB 3.44Å; H454-L458 PolarHBondContact O-N 3.17Å; K455-L458 PolarHBondContact O-N 3.26Å; L458-R460 VanDerWaalsContact C-N 3.27Å; L458-R460 PolarHBondContact O-N 3.45Å; L458-R461 PolarHBondContact O-N 3.49Å; L458-L462 HydrophobicContact CD1-CD1 3.84Å; L458-L462 HydrophobicContact CD1-CD2 4.25Å; L458-L462 HydrophobicContact CD1-CG 3.77Å; L458-L462 HydrophobicContact CD2-CD1 4.36Å; L458-L462 HydrophobicContact CG-CD1 3.84Å; L458-L462 HydrophobicContact CG-CG 4.14Å; L458-L462 WeakPolarHBondContact O-CB 3.37Å; L458-L462 WeakPolarHBondContact O-CG 3.27Å; L458-L462 PolarHBondContact O-N 3.43Å; L458-E473 HydrophobicContact CD1-CG 4.09Å; L458-E473 WeakPolarHBondContact CD1-OE1 3.21Å; L458-L493 HydrophobicContact CD2-CB 4.06Å; L458-L493 HydrophobicContact CD2-CD2 3.74Å; L458-L493 HydrophobicContact CD2-CG 4.31Å; L458-M496 HydrophobicContact CD2-CE 4.06Å; L458-M496 HydrophobicContact CD2-SD 4.2Å; L458-M496 HydrophobicContact CG-CE 4.06Å; L458-F497 HydrophobicContact CD1-CE2 4.07Å; L458-F497 HydrophobicContact CD1-CZ 3.74Å; L458-F497 HydrophobicContact CD2-CE2 4.04Å
459T89.6Confident89.9Confident17 Ų1725.6 Ų25.610%0.10414%0.135CC..Hα-helixtrans-51.8-50.1176.5-64.20000110.3K455 A456 H457 R461 I463 M496 W536 M577K455-T459 WeakPolarHBondContact O-CB 3.45Å; K455-T459 PolarHBondContact O-N 3.32Å; K455-T459 PolarHBondContact O-OG1 3.38Å; A456-T459 WeakPolarHBondContact O-CB 3.25Å; A456-T459 PolarHBondContact O-N 3.42Å; H457-T459 VanDerWaalsContact C-N 3.35Å; H457-T459 PolarHBondContact O-N 2.85Å; T459-R461 PolarHBondContact O-N 3.07Å; T459-I463 HydrophobicContact CG2-CG1 4.42Å; T459-I463 WeakPolarHBondContact O-CB 3.47Å; T459-I463 WeakPolarHBondContact O-CG1 3.18Å; T459-I463 PolarHBondContact O-N 3.01Å; T459-M496 WeakPolarHBondContact OG1-CE 3.39Å; T459-W536 HydrophobicContact CG2-CE3 3.76Å; T459-W536 HydrophobicContact CG2-CZ3 3.85Å; T459-M577 HydrophobicContact CG2-CE 3.44Å; T459-M577 VanDerWaalsContact CG2-CE 3.44Å
460R85Confident90Very high23 Ų2329.1 Ų29.19%0.08716%0.16CC..Hα-helixtrans-59.4-48.2177-179.8-172-167.3107.418.1112.4A456 H457 L458 I463 L464 I466 G690 R691 L692 L694A456-R460 PolarHBondContact O-N 2.76Å; A456-R460 VanDerWaalsContact O-N 3.11Å; H457-R460 WeakPolarHBondContact O-CB 3.47Å; H457-R460 PolarHBondContact O-N 3.2Å; L458-R460 VanDerWaalsContact C-N 3.27Å; L458-R460 PolarHBondContact O-N 3.45Å; R460-I463 PolarHBondContact O-N 3.27Å; R460-L464 HydrophobicContact CG-CD1 3.77Å; R460-L464 HydrophobicContact CG-CG 4.49Å; R460-L464 WeakPolarHBondContact O-CB 3.31Å; R460-L464 WeakPolarHBondContact O-CG 3.22Å; R460-L464 PolarHBondContact O-N 3.1Å; R460-I466 HydrophobicContact CG-CD1 4.36Å; R460-G690 PolarHBondContact NH2-O 3.41Å; R460-R691 VanDerWaalsContact NH2-CA 3.27Å; R460-L692 PolarHBondContact NH1-O 2.74Å; R460-L692 PolarHBondContact NH2-O 2.87Å; R460-L694 HydrophobicContact CB-CD1 3.53Å; R460-L694 HydrophobicContact CG-CD1 3.5Å; R460-L694 VanDerWaalsContact CG-CD1 3.5Å
461R91Very high90Very high0 Ų035.8 Ų35.80%019%0.191CC..Hα-helixtrans-64.1-43.9-175.5-70.1-169.4-54.6-92.9-1.9111.8D413 R417 H457 L458 T459 D465 I466 E473D413-R461 IonicContact OD1-CZ 3.7Å; D413-R461 IonicContact OD1-NH1 2.94Å; D413-R461 PolarHBondContact OD1-NH1 3.24Å; R417-R461 HydrophobicContact CB-CG 4.39Å; H457-R461 WeakPolarHBondContact O-CG 2.97Å; H457-R461 PolarHBondContact O-N 3.42Å; L458-R461 PolarHBondContact O-N 3.49Å; T459-R461 PolarHBondContact O-N 3.07Å; R461-D465 WeakPolarHBondContact O-CA 3.37Å; R461-D465 PolarHBondContact O-N 3.34Å; R461-I466 HydrophobicContact CB-CG1 4.22Å; R461-I466 HydrophobicContact CG-CD1 4.46Å; R461-I466 HydrophobicContact CG-CG1 4.11Å; R461-I466 PolarHBondContact O-N 2.96Å; R461-I466 VanDerWaalsContact O-N 3.15Å; R461-E473 IonicContact CZ-OE1 2.7Å; R461-E473 IonicContact NE-OE1 2.87Å; R461-E473 PolarHBondContact NE-OE1 3.38Å; R461-E473 IonicContact NH2-OE1 3.95Å; R461-E473 PolarHBondContact NH2-OE1 3.1Å
462L92Very high90.1Very high14 Ų1435.9 Ų35.97%0.07319%0.191CC..Hα-helixtrans-68.1-39177.6-67.1-177.3000113.3L458 M496 F497 I500 K529 W536L458-L462 HydrophobicContact CD1-CD1 3.84Å; L458-L462 HydrophobicContact CD1-CD2 4.25Å; L458-L462 HydrophobicContact CD1-CG 3.77Å; L458-L462 HydrophobicContact CD2-CD1 4.36Å; L458-L462 HydrophobicContact CG-CD1 3.84Å; L458-L462 HydrophobicContact CG-CG 4.14Å; L458-L462 WeakPolarHBondContact O-CB 3.37Å; L458-L462 WeakPolarHBondContact O-CG 3.27Å; L458-L462 PolarHBondContact O-N 3.43Å; L462-M496 HydrophobicContact CD1-CB 3.99Å; L462-M496 HydrophobicContact CD1-CE 4.26Å; L462-F497 HydrophobicContact CD2-CD1 4.09Å; L462-F497 HydrophobicContact CD2-CE1 3.78Å; L462-F497 HydrophobicContact CD2-CZ 4.39Å; L462-I500 HydrophobicContact CB-CD1 4.24Å; L462-I500 HydrophobicContact CB-CG1 4.12Å; L462-I500 HydrophobicContact CD1-CG1 4.21Å; L462-I500 HydrophobicContact CD2-CG1 4.48Å; L462-K529 PolarHBondContact O-NZ 3.26Å; L462-W536 HydrophobicContact CB-CH2 3.73Å; L462-W536 HydrophobicContact CB-CZ3 4.39Å; L462-W536 HydrophobicContact CD1-CH2 3.85Å; L462-W536 HydrophobicContact CD1-CZ2 4.24Å; L462-W536 HydrophobicContact CG-CH2 4.47Å
463I88.5Confident90.3Very high22 Ų2232.1 Ų32.111%0.11318%0.178CC..Hα-helixtrans-69.3-43.6178.7-66.9-67.1000111.3T459 R460 K529 L531 W536 M577T459-I463 HydrophobicContact CG2-CG1 4.42Å; T459-I463 WeakPolarHBondContact O-CB 3.47Å; T459-I463 WeakPolarHBondContact O-CG1 3.18Å; T459-I463 PolarHBondContact O-N 3.01Å; R460-I463 PolarHBondContact O-N 3.27Å; I463-K529 HydrophobicContact CD1-CD 4.18Å; I463-K529 PolarHBondContact O-NZ 3.21Å; I463-L531 HydrophobicContact CD1-CD1 3.49Å; I463-L531 VanDerWaalsContact CD1-CD1 3.49Å; I463-W536 HydrophobicContact CD1-CE3 4.39Å; I463-W536 HydrophobicContact CD1-CH2 4.07Å; I463-W536 HydrophobicContact CD1-CZ3 3.71Å; I463-W536 HydrophobicContact CG1-CH2 4.31Å; I463-W536 HydrophobicContact CG1-CZ3 3.71Å; I463-M577 HydrophobicContact CD1-CE 3.87Å; I463-M577 HydrophobicContact CG1-CE 3.65Å; I463-M577 WeakPolarHBondContact CG2-O 3.44Å
464L85.6Confident90.6Very high22 Ų2234.9 Ų34.912%0.11519%0.191CC..Hα-helixtrans-88-5.4-175.5-57.8179000113.9R460 I466 N579 I689 L692R460-L464 HydrophobicContact CG-CD1 3.77Å; R460-L464 HydrophobicContact CG-CG 4.49Å; R460-L464 WeakPolarHBondContact O-CB 3.31Å; R460-L464 WeakPolarHBondContact O-CG 3.22Å; R460-L464 PolarHBondContact O-N 3.1Å; L464-I466 VanDerWaalsContact C-N 3.34Å; L464-I466 HydrophobicContact CB-CD1 4.09Å; L464-I466 HydrophobicContact CB-CG1 4.06Å; L464-I466 HydrophobicContact CB-CG2 3.9Å; L464-I466 HydrophobicContact CD1-CD1 4.07Å; L464-I466 WeakPolarHBondContact O-CG2 3.19Å; L464-I466 PolarHBondContact O-N 3.33Å; L464-N579 WeakPolarHBondContact CD2-ND2 3.16Å; L464-I689 HydrophobicContact CD1-CG2 4.4Å; L464-I689 HydrophobicContact CD2-CD1 4.33Å; L464-L692 HydrophobicContact CD1-CD1 3.9Å; L464-L692 HydrophobicContact CD2-CD1 3.82Å; L464-L692 HydrophobicContact CG-CD1 4.39Å
465D88.6Confident90.7Very high110 Ų11037.3 Ų37.359%0.58820%0.204SC*.THydrogen-bonded Turntrans55.246.5-176.5-170.731.3000113.3K418 R461K418-D465 PolarHBondContact NZ-O 3Å; R461-D465 WeakPolarHBondContact O-CA 3.37Å; R461-D465 PolarHBondContact O-N 3.34Å
466I89.4Confident91Very high37 Ų3735.9 Ų35.919%0.1920%0.198CC..  trans-112.415.5-174.860.9175.7000113.5R417 K418 R460 R461 L464R417-I466 CarbonylContact C-O 3.58Å; R417-I466 WeakPolarHBondContact CA-O 3.43Å; R417-I466 HydrophobicContact CG-CB 4.38Å; R417-I466 HydrophobicContact CG-CD1 3.98Å; R417-I466 HydrophobicContact CG-CG1 4.16Å; K418-I466 WeakPolarHBondContact CG-O 3.43Å; K418-I466 PolarHBondContact N-O 3.24Å; R460-I466 HydrophobicContact CG-CD1 4.36Å; R461-I466 HydrophobicContact CB-CG1 4.22Å; R461-I466 HydrophobicContact CG-CD1 4.46Å; R461-I466 HydrophobicContact CG-CG1 4.11Å; R461-I466 PolarHBondContact O-N 2.96Å; R461-I466 VanDerWaalsContact O-N 3.15Å; L464-I466 VanDerWaalsContact C-N 3.34Å; L464-I466 HydrophobicContact CB-CD1 4.09Å; L464-I466 HydrophobicContact CB-CG1 4.06Å; L464-I466 HydrophobicContact CB-CG2 3.9Å; L464-I466 HydrophobicContact CD1-CD1 4.07Å; L464-I466 WeakPolarHBondContact O-CG2 3.19Å; L464-I466 PolarHBondContact O-N 3.33Å
467S92.3Very high91.4Very high8 Ų834.7 Ų34.76%0.05619%0.188CC..BIsolated β-bridgetrans-67.3134.4175.9-57.70000111.5L416 K418 E473L416-S467 CarbonylContact O-C 3.42Å; L416-S467 WeakPolarHBondContact O-CA 3.46Å; K418-S467 WeakPolarHBondContact CE-O 3.34Å; S467-E473 WeakPolarHBondContact CB-OE2 3.39Å; S467-E473 PolarHBondContact OG-OE2 2.93Å
468A91.3Very high91.7Very high39 Ų3936.9 Ų36.932%0.32220%0.198SC..SBendtrans-68.3-42.2-179.300000111.6L416L416-A468 PolarHBondContact O-N 2.86Å
469D92.4Very high91.9Very high39 Ų3938.1 Ų38.121%0.20920%0.202CC..  trans-149.3118.7-178.5-172.3-37000108.3S427 E471 I472 E473S427-D469 PolarHBondContact OG-OD2 3.36Å; D469-E471 PolarHBondContact OD1-N 2.94Å; D469-I472 HydrophobicContact CB-CB 4.14Å; D469-I472 HydrophobicContact CB-CD1 3.97Å; D469-I472 HydrophobicContact CB-CG1 4.07Å; D469-I472 PolarHBondContact OD1-N 3.19Å; D469-E473 PolarHBondContact O-N 3.39Å
470S91.1Very high92.2Very high76 Ų7637.3 Ų37.353%0.53120%0.197SC..Hα-helixtrans-72.4-30.6-176.1-56.50000112.6E473 E474S470-E473 PolarHBondContact O-N 3.49Å; S470-E474 PolarHBondContact O-N 3.19Å; S470-E474 VanDerWaalsContact O-N 3.11Å
471E93.4Very high92.6Very high140 Ų14041.3 Ų41.365%0.65421%0.212SC*.Hα-helixtrans-71.2-44.7-179.6-174.8175.817900110.3D469 E473 E474 N475D469-E471 PolarHBondContact OD1-N 2.94Å; E471-E473 PolarHBondContact O-N 3.4Å; E471-E474 PolarHBondContact O-N 3.27Å; E471-N475 WeakPolarHBondContact O-CB 3.26Å; E471-N475 VanDerWaalsContact O-CG 3.31Å; E471-N475 PolarHBondContact O-N 3.17Å; E471-N475 PolarHBondContact O-ND2 3.19Å
472I95.3Very high92.6Very high8 Ų848.6 Ų48.64%0.04125%0.247CC..Hα-helixtrans-59.9-36.5173.2-63.6-179.3000110.8L416 S427 I430 L434 D469 N475 M476 W479L416-I472 HydrophobicContact CD2-CG2 3.73Å; S427-I472 WeakPolarHBondContact O-CD1 3.46Å; I430-I472 HydrophobicContact CB-CD1 4.22Å; I430-I472 HydrophobicContact CG2-CD1 4.03Å; I430-I472 HydrophobicContact CG2-CG2 4.31Å; L434-I472 HydrophobicContact CD1-CG2 3.53Å; D469-I472 HydrophobicContact CB-CB 4.14Å; D469-I472 HydrophobicContact CB-CD1 3.97Å; D469-I472 HydrophobicContact CB-CG1 4.07Å; D469-I472 PolarHBondContact OD1-N 3.19Å; I472-N475 PolarHBondContact O-N 2.87Å; I472-M476 WeakPolarHBondContact O-CB 3.49Å; I472-M476 PolarHBondContact O-N 2.97Å; I472-W479 HydrophobicContact CG2-CH2 4.4Å; I472-W479 HydrophobicContact CG2-CZ3 4.37Å
473E92.3Very high92.6Very high4 Ų448.8 Ų48.82%0.01925%0.248CC..Hα-helixtrans-69-36.3180-142.5174.5-177.300113.1L416 L458 R461 S467 D469 S470 E471 F497L416-E473 HydrophobicContact CD2-CG 4.44Å; L458-E473 HydrophobicContact CD1-CG 4.09Å; L458-E473 WeakPolarHBondContact CD1-OE1 3.21Å; R461-E473 IonicContact CZ-OE1 2.7Å; R461-E473 IonicContact NE-OE1 2.87Å; R461-E473 PolarHBondContact NE-OE1 3.38Å; R461-E473 IonicContact NH2-OE1 3.95Å; R461-E473 PolarHBondContact NH2-OE1 3.1Å; S467-E473 WeakPolarHBondContact CB-OE2 3.39Å; S467-E473 PolarHBondContact OG-OE2 2.93Å; D469-E473 PolarHBondContact O-N 3.39Å; S470-E473 PolarHBondContact O-N 3.49Å; E471-E473 PolarHBondContact O-N 3.4Å; E473-F497 HydrophobicContact CB-CE1 4.15Å; E473-F497 HydrophobicContact CB-CZ 3.97Å; E473-F497 HydrophobicContact CG-CE1 4.35Å; E473-F497 HydrophobicContact CG-CZ 3.85Å; E473-F497 WeakPolarHBondContact O-CZ 3.09Å
474E93.9Very high92.6Very high74 Ų7449.5 Ų49.535%0.34626%0.261SS..Hα-helixtrans-67.9-43.6170.4-71-171.7-15500111.1S470 E471 M476 V477 F497 K501S470-E474 PolarHBondContact O-N 3.19Å; S470-E474 VanDerWaalsContact O-N 3.11Å; E471-E474 PolarHBondContact O-N 3.27Å; E474-M476 VanDerWaalsContact C-N 3.28Å; E474-M476 PolarHBondContact O-N 3.41Å; E474-V477 WeakPolarHBondContact O-CB 3.38Å; E474-V477 PolarHBondContact O-N 3.27Å; E474-V477 VanDerWaalsContact O-N 3.08Å; E474-F497 HydrophobicContact CG-CD1 3.81Å; E474-F497 HydrophobicContact CG-CE1 3.91Å; E474-F497 HydrophobicContact CG-CG 4.24Å; E474-F497 HydrophobicContact CG-CZ 4.43Å; E474-K501 VanDerWaalsContact CD-NZ 3.31Å; E474-K501 WeakPolarHBondContact OE1-CE 3.3Å; E474-K501 IonicContact OE1-NZ 2.71Å; E474-K501 PolarHBondContact OE1-NZ 3.2Å; E474-K501 IonicContact OE2-NZ 3.66Å; E474-K501 PolarHBondContact OE2-NZ 3.43Å; E474-K501 VanDerWaalsContact OE2-NZ 3.08Å
475N95.6Very high92.8Very high55 Ų5548.8 Ų48.829%0.29426%0.257SS..Hα-helixtrans-60.5-35.7176.7-72.3-21.1000112.7E471 I472 V477 E478 W479E471-N475 WeakPolarHBondContact O-CB 3.26Å; E471-N475 VanDerWaalsContact O-CG 3.31Å; E471-N475 PolarHBondContact O-N 3.17Å; E471-N475 PolarHBondContact O-ND2 3.19Å; I472-N475 PolarHBondContact O-N 2.87Å; N475-V477 PolarHBondContact O-N 2.91Å; N475-E478 PolarHBondContact O-N 3.17Å; N475-W479 HydrophobicContact CB-CD2 4.42Å; N475-W479 HydrophobicContact CB-CH2 3.98Å; N475-W479 HydrophobicContact CB-CZ2 3.69Å; N475-W479 HydrophobicContact CB-CZ3 4.49Å; N475-W479 VanDerWaalsContact O-CG 3.3Å; N475-W479 PolarHBondContact O-N 3.3Å
476M95.8Very high92.8Very high1 Ų144.6 Ų44.61%0.00524%0.236CC..Hα-helixtrans-57.1-34.1176-174.365.3-174.700112.2L416 L434 L438 F450 I472 E474 W479 L480L416-M476 HydrophobicContact CD1-CG 4.28Å; L434-M476 HydrophobicContact CD2-SD 4.34Å; L438-M476 HydrophobicContact CD1-SD 4.45Å; L438-M476 HydrophobicContact CD2-CE 3.84Å; L438-M476 HydrophobicContact CG-CE 4.43Å; F450-M476 HydrophobicContact CZ-CE 4.3Å; I472-M476 WeakPolarHBondContact O-CB 3.49Å; I472-M476 PolarHBondContact O-N 2.97Å; E474-M476 VanDerWaalsContact C-N 3.28Å; E474-M476 PolarHBondContact O-N 3.41Å; M476-W479 HydrophobicContact CB-CE3 4.47Å; M476-W479 HydrophobicContact SD-CE3 4.07Å; M476-L480 HydrophobicContact CE-CD1 4.4Å; M476-L480 HydrophobicContact CE-CD2 4.14Å; M476-L480 HydrophobicContact CE-CG 4.18Å; M476-L480 HydrophobicContact CG-CD1 4.46Å; M476-L480 WeakPolarHBondContact O-CB 3.13Å; M476-L480 VanDerWaalsContact O-CG 3.23Å; M476-L480 WeakPolarHBondContact O-CG 3.28Å; M476-L480 PolarHBondContact O-N 2.78Å
477V95.3Very high92.8Very high5 Ų545.8 Ų45.83%0.0325%0.251CS..Hα-helixtrans-67.3-41.2177-179.10000111.2E474 N475 R481 V490 L493 A494 F497E474-V477 WeakPolarHBondContact O-CB 3.38Å; E474-V477 PolarHBondContact O-N 3.27Å; E474-V477 VanDerWaalsContact O-N 3.08Å; N475-V477 PolarHBondContact O-N 2.91Å; V477-R481 PolarHBondContact O-N 3.46Å; V477-V490 HydrophobicContact CG1-CG1 3.63Å; V477-L493 HydrophobicContact CG1-CB 4.28Å; V477-L493 HydrophobicContact CG2-CB 4.09Å; V477-A494 HydrophobicContact CG1-CB 4.24Å; V477-F497 HydrophobicContact CG2-CD2 4.16Å; V477-F497 HydrophobicContact CG2-CE2 3.57Å; V477-F497 HydrophobicContact CG2-CZ 4.48Å
478E94.7Very high92.7Very high79 Ų7947.6 Ų47.637%0.36926%0.26SS..Hα-helixtrans-68.7-43176.7-66.5-58.7140.500111.2N475 L480 R481 E482N475-E478 PolarHBondContact O-N 3.17Å; E478-L480 VanDerWaalsContact C-N 3.31Å; E478-L480 PolarHBondContact O-N 3.49Å; E478-R481 WeakPolarHBondContact O-CA 3.38Å; E478-R481 WeakPolarHBondContact O-CB 2.77Å; E478-R481 PolarHBondContact O-N 2.9Å; E478-R481 IonicContact OE1-CZ 3.38Å; E478-R481 VanDerWaalsContact OE1-CZ 3.32Å; E478-R481 IonicContact OE1-NH1 3.7Å; E478-R481 PolarHBondContact OE1-NH1 3.39Å; E478-R481 IonicContact OE1-NH2 3.11Å; E478-R481 PolarHBondContact OE1-NH2 3.44Å; E478-R481 IonicContact OE2-CZ 2.71Å; E478-R481 IonicContact OE2-NE 3.97Å; E478-R481 IonicContact OE2-NH1 2.7Å; E478-R481 PolarHBondContact OE2-NH1 3.34Å; E478-R481 IonicContact OE2-NH2 3.53Å; E478-R481 PolarHBondContact OE2-NH2 2.94Å; E478-E482 PolarHBondContact O-N 2.83Å; E478-E482 VanDerWaalsContact O-N 3.1Å
479W96.4Very high92.6Very high27 Ų2747 Ų4710%0.10225%0.25CC..Hα-helixtrans-63.8-34.6176.1-56.7-29.4000113E431 L434 L438 I472 N475 M476 R481 E482 V483E431-W479 HydrophobicContact CB-CH2 4.07Å; E431-W479 HydrophobicContact CG-CH2 3.51Å; E431-W479 HydrophobicContact CG-CZ2 3.86Å; E431-W479 HydrophobicContact CG-CZ3 4.43Å; L434-W479 HydrophobicContact CB-CZ3 4.18Å; L434-W479 HydrophobicContact CD1-CZ3 4.13Å; L438-W479 HydrophobicContact CD1-CB 3.41Å; L438-W479 VanDerWaalsContact CD1-CB 3.41Å; L438-W479 HydrophobicContact CD1-CD2 4.48Å; L438-W479 HydrophobicContact CD1-CE3 4.24Å; L438-W479 HydrophobicContact CD1-CG 4.21Å; I472-W479 HydrophobicContact CG2-CH2 4.4Å; I472-W479 HydrophobicContact CG2-CZ3 4.37Å; N475-W479 HydrophobicContact CB-CD2 4.42Å; N475-W479 HydrophobicContact CB-CH2 3.98Å; N475-W479 HydrophobicContact CB-CZ2 3.69Å; N475-W479 HydrophobicContact CB-CZ3 4.49Å; N475-W479 VanDerWaalsContact O-CG 3.3Å; N475-W479 PolarHBondContact O-N 3.3Å; M476-W479 HydrophobicContact CB-CE3 4.47Å; M476-W479 HydrophobicContact SD-CE3 4.07Å; W479-R481 VanDerWaalsContact C-N 3.28Å; W479-R481 PolarHBondContact O-N 3.47Å; W479-E482 PolarHBondContact O-N 3.18Å; W479-V483 WeakPolarHBondContact O-CG2 3.45Å; W479-V483 PolarHBondContact O-N 2.93Å; W479-V483 VanDerWaalsContact O-N 3.07Å
480L95.6Very high92.6Very high0 Ų045.1 Ų45.10%024%0.24CC..Hα-helixtrans-62.7-36172.4-75.3171.9000111.8L438 L441 F450 M451 M476 E478 V483 M485 L493L438-L480 HydrophobicContact CD2-CD2 3.83Å; L441-L480 HydrophobicContact CD2-CD2 3.88Å; F450-L480 HydrophobicContact CE1-CD1 4.5Å; F450-L480 HydrophobicContact CE1-CD2 3.58Å; F450-L480 HydrophobicContact CZ-CD2 4.14Å; M451-L480 HydrophobicContact CE-CD1 4.35Å; M451-L480 HydrophobicContact SD-CD1 4.3Å; M451-L480 HydrophobicContact SD-CD2 4.43Å; M476-L480 HydrophobicContact CE-CD1 4.4Å; M476-L480 HydrophobicContact CE-CD2 4.14Å; M476-L480 HydrophobicContact CE-CG 4.18Å; M476-L480 HydrophobicContact CG-CD1 4.46Å; M476-L480 WeakPolarHBondContact O-CB 3.13Å; M476-L480 VanDerWaalsContact O-CG 3.23Å; M476-L480 WeakPolarHBondContact O-CG 3.28Å; M476-L480 PolarHBondContact O-N 2.78Å; E478-L480 VanDerWaalsContact C-N 3.31Å; E478-L480 PolarHBondContact O-N 3.49Å; L480-V483 PolarHBondContact O-N 3.47Å; L480-M485 HydrophobicContact CB-CB 4.43Å; L480-M485 HydrophobicContact CB-CG 4.01Å; L480-M485 HydrophobicContact CD2-CG 3.97Å; L480-M485 WeakPolarHBondContact O-CB 3.5Å; L480-M485 WeakPolarHBondContact O-CG 3.09Å; L480-M485 PolarHBondContact O-N 3.04Å; L480-M485 VanDerWaalsContact O-N 3.1Å; L480-L493 HydrophobicContact CD1-CD1 4.06Å
481R93.5Very high92.8Very high107 Ų10746 Ų4640%0.40424%0.238SC..Hα-helixtrans-62-46.1172.9-164.6-176.6-67149.314.5111.1V477 E478 W479 V483 G484 V490V477-R481 PolarHBondContact O-N 3.46Å; E478-R481 WeakPolarHBondContact O-CA 3.38Å; E478-R481 WeakPolarHBondContact O-CB 2.77Å; E478-R481 PolarHBondContact O-N 2.9Å; E478-R481 IonicContact OE1-CZ 3.38Å; E478-R481 VanDerWaalsContact OE1-CZ 3.32Å; E478-R481 IonicContact OE1-NH1 3.7Å; E478-R481 PolarHBondContact OE1-NH1 3.39Å; E478-R481 IonicContact OE1-NH2 3.11Å; E478-R481 PolarHBondContact OE1-NH2 3.44Å; E478-R481 IonicContact OE2-CZ 2.71Å; E478-R481 IonicContact OE2-NE 3.97Å; E478-R481 IonicContact OE2-NH1 2.7Å; E478-R481 PolarHBondContact OE2-NH1 3.34Å; E478-R481 IonicContact OE2-NH2 3.53Å; E478-R481 PolarHBondContact OE2-NH2 2.94Å; W479-R481 VanDerWaalsContact C-N 3.28Å; W479-R481 PolarHBondContact O-N 3.47Å; R481-V483 VanDerWaalsContact C-N 3.32Å; R481-V483 PolarHBondContact O-N 3.2Å; R481-G484 PolarHBondContact O-N 3.13Å; R481-V490 HydrophobicContact CB-CG1 4.19Å; R481-V490 HydrophobicContact CB-CG2 4.47Å
482E92.3Very high92.8Very high154 Ų15442.8 Ų42.872%0.7222%0.222SC*.Hα-helixtrans-63.6-32.7-179.7-66.6177.5172.800113.5E478 W479 G484E478-E482 PolarHBondContact O-N 2.83Å; E478-E482 VanDerWaalsContact O-N 3.1Å; W479-E482 PolarHBondContact O-N 3.18Å; E482-G484 PolarHBondContact O-N 3.12Å
483V90.5Very high92.8Very high18 Ų1842.5 Ų42.511%0.10922%0.221CC..THydrogen-bonded Turntrans-75.20.3176.1173.60000112.6L438 L441 K442 K447 W479 L480 R481 M485L438-V483 HydrophobicContact CB-CG2 4.01Å; L438-V483 HydrophobicContact CD1-CG2 4.42Å; L438-V483 HydrophobicContact CD2-CG2 4.27Å; L438-V483 HydrophobicContact CG-CG2 4.47Å; L441-V483 HydrophobicContact CD2-CG1 4.39Å; L441-V483 HydrophobicContact CG-CG1 4.39Å; K442-V483 HydrophobicContact CG-CG1 3.8Å; K447-V483 PolarHBondContact NZ-O 3.41Å; W479-V483 WeakPolarHBondContact O-CG2 3.45Å; W479-V483 PolarHBondContact O-N 2.93Å; W479-V483 VanDerWaalsContact O-N 3.07Å; L480-V483 PolarHBondContact O-N 3.47Å; R481-V483 VanDerWaalsContact C-N 3.32Å; R481-V483 PolarHBondContact O-N 3.2Å; V483-M485 HydrophobicContact CG1-CE 4Å
484G88.8Confident92.9Very high36 Ų3644 Ų4437%0.37123%0.234SC..THydrogen-bonded Turntrans80.530178.100000113.1R481 E482R481-G484 PolarHBondContact O-N 3.13Å; E482-G484 PolarHBondContact O-N 3.12Å
485M91.1Very high93Very high8 Ų844.7 Ų44.74%0.03923%0.234CC..  trans-66.1143167.6-67.3-62.3129.700110.2L441 K447 M451 L480 V483 A487 V490L441-M485 HydrophobicContact CD1-CE 4.28Å; L441-M485 HydrophobicContact CD2-CE 3.69Å; L441-M485 HydrophobicContact CG-CE 3.79Å; K447-M485 HydrophobicContact CB-CE 3.95Å; K447-M485 HydrophobicContact CB-SD 3.92Å; K447-M485 HydrophobicContact CD-CE 3.39Å; K447-M485 HydrophobicContact CD-SD 4.21Å; K447-M485 HydrophobicContact CG-CE 3.71Å; K447-M485 HydrophobicContact CG-SD 4.37Å; M451-M485 HydrophobicContact CG-SD 3.89Å; M451-M485 HydrophobicContact SD-CB 4.48Å; M451-M485 HydrophobicContact SD-CG 3.94Å; M451-M485 HydrophobicContact SD-SD 3.8Å; L480-M485 HydrophobicContact CB-CB 4.43Å; L480-M485 HydrophobicContact CB-CG 4.01Å; L480-M485 HydrophobicContact CD2-CG 3.97Å; L480-M485 WeakPolarHBondContact O-CB 3.5Å; L480-M485 WeakPolarHBondContact O-CG 3.09Å; L480-M485 PolarHBondContact O-N 3.04Å; L480-M485 VanDerWaalsContact O-N 3.1Å; V483-M485 HydrophobicContact CG1-CE 4Å; M485-A487 PolarHBondContact O-N 3.27Å; M485-V490 HydrophobicContact CB-CG2 3.89Å
486P87.7Confident93Very high21 Ų2142.1 Ų42.114%0.13622%0.22CC..  trans-52.6132.7175.9-25.831.2000112.9D488 Y489 V490 M745P486-D488 WeakPolarHBondContact CB-OD1 3.38Å; P486-D488 PolarHBondContact O-N 3.08Å; P486-Y489 HydrophobicContact CB-CD2 3.79Å; P486-Y489 HydrophobicContact CB-CE2 4.28Å; P486-Y489 HydrophobicContact CB-CG 4.46Å; P486-Y489 HydrophobicContact CG-CD2 3.68Å; P486-Y489 HydrophobicContact CG-CE2 3.9Å; P486-Y489 PolarHBondContact O-N 3Å; P486-V490 PolarHBondContact O-N 2.73Å; P486-M745 HydrophobicContact CB-CG 4.41Å; P486-M745 HydrophobicContact CG-CB 4.48Å; P486-M745 HydrophobicContact CG-CG 3.46Å; P486-M745 VanDerWaalsContact CG-CG 3.46Å; P486-M745 HydrophobicContact CG-SD 4.39Å
487A90.2Very high92.9Very high62 Ų6243 Ų4351%0.51222%0.224SC..Hα-helixtrans-58.8-32.9-177.100000112.8M485 Y489 V490 N491M485-A487 PolarHBondContact O-N 3.27Å; A487-Y489 VanDerWaalsContact C-N 3.32Å; A487-Y489 PolarHBondContact O-N 3.45Å; A487-V490 PolarHBondContact O-N 2.89Å; A487-N491 VanDerWaalsContact O-CB 3.22Å; A487-N491 WeakPolarHBondContact O-CB 3.48Å; A487-N491 PolarHBondContact O-N 2.7Å; A487-N491 PolarHBondContact O-ND2 2.89Å
488D88.6Confident92.9Very high47 Ų4747.5 Ų47.525%0.25125%0.245SC..Hα-helixtrans-66.7-31.8178.772.3-59.9000112.9P486 K492 R714P486-D488 WeakPolarHBondContact CB-OD1 3.38Å; P486-D488 PolarHBondContact O-N 3.08Å; D488-K492 WeakPolarHBondContact O-CD 3.48Å; D488-K492 VanDerWaalsContact O-CG 3.27Å; D488-K492 WeakPolarHBondContact O-CG 3.16Å; D488-K492 PolarHBondContact O-N 3.33Å; D488-K492 IonicContact OD2-NZ 2.64Å; D488-R714 IonicContact OD2-CZ 3.84Å; D488-R714 IonicContact OD2-NH2 3.45Å; D488-R714 PolarHBondContact OD2-NH2 3.33Å
489Y89.9Confident92.9Very high25 Ų2544 Ų4410%0.09823%0.228CC..Hα-helixtrans-73.2-48.5172.9-65.7-40.5000111.2D448 M451 P486 A487 N491 K492 L493 L710 M745D448-Y489 HydrophobicContact CB-CE2 4.5Å; M451-Y489 HydrophobicContact CB-CD2 4.16Å; M451-Y489 HydrophobicContact CB-CE2 4.49Å; M451-Y489 HydrophobicContact CB-CG 4.38Å; M451-Y489 HydrophobicContact CE-CG 4.4Å; M451-Y489 HydrophobicContact CG-CD2 3.92Å; M451-Y489 HydrophobicContact CG-CE2 4.5Å; M451-Y489 HydrophobicContact CG-CG 4.37Å; P486-Y489 HydrophobicContact CB-CD2 3.79Å; P486-Y489 HydrophobicContact CB-CE2 4.28Å; P486-Y489 HydrophobicContact CB-CG 4.46Å; P486-Y489 HydrophobicContact CG-CD2 3.68Å; P486-Y489 HydrophobicContact CG-CE2 3.9Å; P486-Y489 PolarHBondContact O-N 3Å; A487-Y489 VanDerWaalsContact C-N 3.32Å; A487-Y489 PolarHBondContact O-N 3.45Å; Y489-N491 VanDerWaalsContact C-N 3.34Å; Y489-N491 PolarHBondContact O-N 2.66Å; Y489-K492 WeakPolarHBondContact O-CB 3.43Å; Y489-K492 PolarHBondContact O-N 2.83Å; Y489-K492 VanDerWaalsContact O-N 3.17Å; Y489-L493 PolarHBondContact O-N 3.48Å; Y489-L710 HydrophobicContact CE1-CD2 4.16Å; Y489-L710 WeakPolarHBondContact OH-CD2 3.35Å; Y489-M745 HydrophobicContact CE2-CE 4.15Å; Y489-M745 WeakPolarHBondContact OH-CE 3.48Å
490V93.7Very high92.8Very high0 Ų043.6 Ų43.60%023%0.228CC..Hα-helixtrans-59.8-44.7-179.6177.60000111V477 R481 M485 P486 A487 K492 L493 A494V477-V490 HydrophobicContact CG1-CG1 3.63Å; R481-V490 HydrophobicContact CB-CG1 4.19Å; R481-V490 HydrophobicContact CB-CG2 4.47Å; M485-V490 HydrophobicContact CB-CG2 3.89Å; P486-V490 PolarHBondContact O-N 2.73Å; A487-V490 PolarHBondContact O-N 2.89Å; V490-K492 VanDerWaalsContact C-N 3.28Å; V490-K492 PolarHBondContact O-N 3.3Å; V490-L493 PolarHBondContact O-N 2.94Å; V490-L493 VanDerWaalsContact O-N 3.08Å; V490-A494 PolarHBondContact O-N 3.31Å
491N94.1Very high92.8Very high94 Ų9448.2 Ų48.250%0.50325%0.248SC..Hα-helixtrans-62.7-33.9178.8-70.7-17.2000112.6A487 Y489 R495A487-N491 VanDerWaalsContact O-CB 3.22Å; A487-N491 WeakPolarHBondContact O-CB 3.48Å; A487-N491 PolarHBondContact O-N 2.7Å; A487-N491 PolarHBondContact O-ND2 2.89Å; Y489-N491 VanDerWaalsContact C-N 3.34Å; Y489-N491 PolarHBondContact O-N 2.66Å; N491-R495 VanDerWaalsContact O-CB 3.29Å; N491-R495 WeakPolarHBondContact O-CB 3.33Å; N491-R495 PolarHBondContact O-N 3.01Å
492K93.3Very high92.8Very high73 Ų7345.9 Ų45.932%0.31725%0.246SC..Hα-helixtrans-66-41.9173.7-73.8166.9-175.3161.40111.2D488 Y489 V490 R495 M496D488-K492 WeakPolarHBondContact O-CD 3.48Å; D488-K492 VanDerWaalsContact O-CG 3.27Å; D488-K492 WeakPolarHBondContact O-CG 3.16Å; D488-K492 PolarHBondContact O-N 3.33Å; D488-K492 IonicContact OD2-NZ 2.64Å; Y489-K492 WeakPolarHBondContact O-CB 3.43Å; Y489-K492 PolarHBondContact O-N 2.83Å; Y489-K492 VanDerWaalsContact O-N 3.17Å; V490-K492 VanDerWaalsContact C-N 3.28Å; V490-K492 PolarHBondContact O-N 3.3Å; K492-R495 PolarHBondContact O-N 2.93Å; K492-M496 VanDerWaalsContact O-CG 3.32Å; K492-M496 WeakPolarHBondContact O-CG 3.48Å; K492-M496 PolarHBondContact O-N 3.38Å; K492-M496 VanDerWaalsContact O-N 3.07Å
493L95.1Very high92.8Very high2 Ų238.7 Ų38.71%0.0121%0.212CC..Hα-helixtrans-64.6-47.5176.4-55.3-175.4000111.1M451 K455 L458 V477 L480 Y489 V490 R495 M496 F497M451-L493 HydrophobicContact CE-CD1 3.75Å; M451-L493 HydrophobicContact CE-CG 4.46Å; K455-L493 HydrophobicContact CB-CD2 3.98Å; K455-L493 HydrophobicContact CG-CD2 3.94Å; L458-L493 HydrophobicContact CD2-CB 4.06Å; L458-L493 HydrophobicContact CD2-CD2 3.74Å; L458-L493 HydrophobicContact CD2-CG 4.31Å; V477-L493 HydrophobicContact CG1-CB 4.28Å; V477-L493 HydrophobicContact CG2-CB 4.09Å; L480-L493 HydrophobicContact CD1-CD1 4.06Å; Y489-L493 PolarHBondContact O-N 3.48Å; V490-L493 PolarHBondContact O-N 2.94Å; V490-L493 VanDerWaalsContact O-N 3.08Å; L493-R495 VanDerWaalsContact C-N 3.26Å; L493-R495 PolarHBondContact O-N 3.32Å; L493-M496 HydrophobicContact CD2-SD 4.08Å; L493-M496 VanDerWaalsContact O-CB 3.32Å; L493-M496 WeakPolarHBondContact O-CB 3.21Å; L493-M496 PolarHBondContact O-N 2.8Å; L493-F497 VanDerWaalsContact O-CD2 3.32Å; L493-F497 WeakPolarHBondContact O-CD2 3.33Å; L493-F497 PolarHBondContact O-N 3.1Å
494A95Very high92.9Very high37 Ų3743 Ų4331%0.30623%0.231SC..Hα-helixtrans-56.9-40.8175.600000111.9V477 V490 M496 F497 Q498V477-A494 HydrophobicContact CG1-CB 4.24Å; V490-A494 PolarHBondContact O-N 3.31Å; A494-M496 VanDerWaalsContact C-N 3.31Å; A494-M496 PolarHBondContact O-N 3.42Å; A494-F497 PolarHBondContact O-N 3.08Å; A494-Q498 PolarHBondContact O-N 3.07Å; A494-Q498 VanDerWaalsContact O-N 3.15Å
495R95.5Very high93.1Very high88 Ų8846.2 Ų46.233%0.33224%0.24SC..Hα-helixtrans-64.4-33.7175.5-173.166-144.7-172.91.4112.8N491 K492 L493 Q498 D499 A535N491-R495 VanDerWaalsContact O-CB 3.29Å; N491-R495 WeakPolarHBondContact O-CB 3.33Å; N491-R495 PolarHBondContact O-N 3.01Å; K492-R495 PolarHBondContact O-N 2.93Å; L493-R495 VanDerWaalsContact C-N 3.26Å; L493-R495 PolarHBondContact O-N 3.32Å; R495-Q498 PolarHBondContact O-N 2.99Å; R495-D499 IonicContact CZ-OD1 3.82Å; R495-D499 VanDerWaalsContact CZ-OD1 3.24Å; R495-D499 IonicContact NE-OD1 2.7Å; R495-D499 PolarHBondContact NE-OD1 3.08Å; R495-D499 IonicContact NH2-OD1 3.73Å; R495-D499 PolarHBondContact NH2-OD1 2.68Å; R495-D499 VanDerWaalsContact O-CG 3.24Å; R495-D499 PolarHBondContact O-N 3.08Å; R495-A535 HydrophobicContact CB-CB 3.93Å; R495-A535 HydrophobicContact CG-CB 3.74Å
496M95.4Very high93.2Very high0 Ų047 Ų470%024%0.244CC..Hα-helixtrans-61.7-43.6175.1-67.2166.96400111.5K455 L458 T459 L462 K492 L493 A494 D499 I500 A535 W536K455-M496 HydrophobicContact CG-SD 4.2Å; L458-M496 HydrophobicContact CD2-CE 4.06Å; L458-M496 HydrophobicContact CD2-SD 4.2Å; L458-M496 HydrophobicContact CG-CE 4.06Å; T459-M496 WeakPolarHBondContact OG1-CE 3.39Å; L462-M496 HydrophobicContact CD1-CB 3.99Å; L462-M496 HydrophobicContact CD1-CE 4.26Å; K492-M496 VanDerWaalsContact O-CG 3.32Å; K492-M496 WeakPolarHBondContact O-CG 3.48Å; K492-M496 PolarHBondContact O-N 3.38Å; K492-M496 VanDerWaalsContact O-N 3.07Å; L493-M496 HydrophobicContact CD2-SD 4.08Å; L493-M496 VanDerWaalsContact O-CB 3.32Å; L493-M496 WeakPolarHBondContact O-CB 3.21Å; L493-M496 PolarHBondContact O-N 2.8Å; A494-M496 VanDerWaalsContact C-N 3.31Å; A494-M496 PolarHBondContact O-N 3.42Å; M496-D499 PolarHBondContact O-N 2.62Å; M496-I500 WeakPolarHBondContact O-CG1 3.08Å; M496-I500 PolarHBondContact O-N 3.45Å; M496-I500 VanDerWaalsContact O-N 3.12Å; M496-A535 HydrophobicContact CG-CB 4.28Å; M496-W536 HydrophobicContact CB-CD2 4.48Å; M496-W536 HydrophobicContact CB-CH2 4.41Å; M496-W536 HydrophobicContact CB-CZ2 3.71Å; M496-W536 HydrophobicContact CE-CD2 3.98Å; M496-W536 HydrophobicContact CE-CE3 3.71Å; M496-W536 HydrophobicContact CE-CH2 4.04Å; M496-W536 HydrophobicContact CE-CZ2 4.29Å; M496-W536 HydrophobicContact CE-CZ3 3.74Å; M496-W536 HydrophobicContact CG-CD2 3.93Å; M496-W536 HydrophobicContact CG-CG 4.13Å; M496-W536 HydrophobicContact CG-CZ2 4.09Å
497F94.9Very high93.4Very high20 Ų2046.6 Ų46.69%0.08824%0.241CC..Hα-helixtrans-62.2-43.3174.2-73.7-82.7000112.3L458 L462 E473 E474 V477 L493 A494 D499 I500 K501L458-F497 HydrophobicContact CD1-CE2 4.07Å; L458-F497 HydrophobicContact CD1-CZ 3.74Å; L458-F497 HydrophobicContact CD2-CE2 4.04Å; L462-F497 HydrophobicContact CD2-CD1 4.09Å; L462-F497 HydrophobicContact CD2-CE1 3.78Å; L462-F497 HydrophobicContact CD2-CZ 4.39Å; E473-F497 HydrophobicContact CB-CE1 4.15Å; E473-F497 HydrophobicContact CB-CZ 3.97Å; E473-F497 HydrophobicContact CG-CE1 4.35Å; E473-F497 HydrophobicContact CG-CZ 3.85Å; E473-F497 WeakPolarHBondContact O-CZ 3.09Å; E474-F497 HydrophobicContact CG-CD1 3.81Å; E474-F497 HydrophobicContact CG-CE1 3.91Å; E474-F497 HydrophobicContact CG-CG 4.24Å; E474-F497 HydrophobicContact CG-CZ 4.43Å; V477-F497 HydrophobicContact CG2-CD2 4.16Å; V477-F497 HydrophobicContact CG2-CE2 3.57Å; V477-F497 HydrophobicContact CG2-CZ 4.48Å; L493-F497 VanDerWaalsContact O-CD2 3.32Å; L493-F497 WeakPolarHBondContact O-CD2 3.33Å; L493-F497 PolarHBondContact O-N 3.1Å; A494-F497 PolarHBondContact O-N 3.08Å; F497-D499 VanDerWaalsContact C-N 3.31Å; F497-D499 PolarHBondContact O-N 3.25Å; F497-I500 PolarHBondContact O-N 3.24Å; F497-K501 PolarHBondContact O-N 2.96Å
498Q95.1Very high93.6Very high100 Ų10049.4 Ų49.447%0.46724%0.243SC..Hα-helixtrans-60.8-41.1176.3-171177.716.400112A494 R495 I500 K501 V502A494-Q498 PolarHBondContact O-N 3.07Å; A494-Q498 VanDerWaalsContact O-N 3.15Å; R495-Q498 PolarHBondContact O-N 2.99Å; Q498-I500 VanDerWaalsContact C-N 3.31Å; Q498-I500 PolarHBondContact O-N 2.91Å; Q498-K501 PolarHBondContact O-N 3.06Å; Q498-V502 HydrophobicContact CG-CG2 4.45Å; Q498-V502 WeakPolarHBondContact O-CB 3.39Å; Q498-V502 VanDerWaalsContact O-CG2 3.28Å; Q498-V502 WeakPolarHBondContact O-CG2 3.29Å; Q498-V502 PolarHBondContact O-N 3.22Å
499D95.1Very high93.7Very high5 Ų549 Ų493%0.02725%0.246CC..Hα-helixtrans-65-33.8177.4-69-16.6000112.2R495 M496 F497 S503 L531 N532 W536R495-D499 IonicContact CZ-OD1 3.82Å; R495-D499 VanDerWaalsContact CZ-OD1 3.24Å; R495-D499 IonicContact NE-OD1 2.7Å; R495-D499 PolarHBondContact NE-OD1 3.08Å; R495-D499 IonicContact NH2-OD1 3.73Å; R495-D499 PolarHBondContact NH2-OD1 2.68Å; R495-D499 VanDerWaalsContact O-CG 3.24Å; R495-D499 PolarHBondContact O-N 3.08Å; M496-D499 PolarHBondContact O-N 2.62Å; F497-D499 VanDerWaalsContact C-N 3.31Å; F497-D499 PolarHBondContact O-N 3.25Å; D499-S503 WeakPolarHBondContact O-CB 3.13Å; D499-S503 PolarHBondContact O-N 3.24Å; D499-S503 PolarHBondContact O-OG 2.95Å; D499-L531 HydrophobicContact CB-CD2 4.17Å; D499-N532 WeakPolarHBondContact OD2-CB 3.45Å; D499-N532 PolarHBondContact OD2-N 3.03Å; D499-W536 PolarHBondContact OD2-NE1 3.42Å; D499-W536 VanDerWaalsContact OD2-NE1 3.13Å
500I94.4Very high93.8Very high19 Ų1947.8 Ų47.810%0.09724%0.242CC..Hα-helixtrans-66-49.9173.4-65.6-59.6000110.9L462 M496 F497 Q498 V502 S503 E504 K529 L531 W536L462-I500 HydrophobicContact CB-CD1 4.24Å; L462-I500 HydrophobicContact CB-CG1 4.12Å; L462-I500 HydrophobicContact CD1-CG1 4.21Å; L462-I500 HydrophobicContact CD2-CG1 4.48Å; M496-I500 WeakPolarHBondContact O-CG1 3.08Å; M496-I500 PolarHBondContact O-N 3.45Å; M496-I500 VanDerWaalsContact O-N 3.12Å; F497-I500 PolarHBondContact O-N 3.24Å; Q498-I500 VanDerWaalsContact C-N 3.31Å; Q498-I500 PolarHBondContact O-N 2.91Å; I500-V502 VanDerWaalsContact C-N 3.34Å; I500-V502 PolarHBondContact O-N 3.33Å; I500-S503 WeakPolarHBondContact O-CA 3.36Å; I500-S503 WeakPolarHBondContact O-CB 3.32Å; I500-S503 PolarHBondContact O-N 3.4Å; I500-E504 PolarHBondContact O-N 2.95Å; I500-K529 HydrophobicContact CD1-CD 4.15Å; I500-L531 HydrophobicContact CD1-CD2 4.16Å; I500-W536 HydrophobicContact CD1-CH2 3.85Å; I500-W536 HydrophobicContact CD1-CZ2 3.9Å; I500-W536 HydrophobicContact CG1-CH2 4.18Å; I500-W536 HydrophobicContact CG1-CZ2 4Å
501K93.8Very high93.6Very high97 Ų9750.7 Ų50.742%0.42225%0.254SS..Hα-helixtrans-57.7-46.1177.7-67.1178.8-177.4176.70111.6E474 F497 Q498 S503 E504 D505E474-K501 VanDerWaalsContact CD-NZ 3.31Å; E474-K501 WeakPolarHBondContact OE1-CE 3.3Å; E474-K501 IonicContact OE1-NZ 2.71Å; E474-K501 PolarHBondContact OE1-NZ 3.2Å; E474-K501 IonicContact OE2-NZ 3.66Å; E474-K501 PolarHBondContact OE2-NZ 3.43Å; E474-K501 VanDerWaalsContact OE2-NZ 3.08Å; F497-K501 PolarHBondContact O-N 2.96Å; Q498-K501 PolarHBondContact O-N 3.06Å; K501-S503 VanDerWaalsContact C-N 3.3Å; K501-S503 PolarHBondContact O-N 3.17Å; K501-E504 WeakPolarHBondContact O-CB 3.5Å; K501-E504 PolarHBondContact O-N 3.43Å; K501-E504 VanDerWaalsContact O-N 3.17Å; K501-D505 PolarHBondContact O-N 3.09Å
502V93.8Very high93.4Very high58 Ų5853.3 Ų53.335%0.35226%0.263SS..Hα-helixtrans-63.2-35.7175.7171.70000112Q498 I500 E504 D505 L506Q498-V502 HydrophobicContact CG-CG2 4.45Å; Q498-V502 WeakPolarHBondContact O-CB 3.39Å; Q498-V502 VanDerWaalsContact O-CG2 3.28Å; Q498-V502 WeakPolarHBondContact O-CG2 3.29Å; Q498-V502 PolarHBondContact O-N 3.22Å; I500-V502 VanDerWaalsContact C-N 3.34Å; I500-V502 PolarHBondContact O-N 3.33Å; V502-E504 VanDerWaalsContact C-N 3.33Å; V502-D505 PolarHBondContact O-N 3Å; V502-L506 HydrophobicContact CG1-CD1 4.07Å; V502-L506 HydrophobicContact CG1-CG 4.45Å; V502-L506 WeakPolarHBondContact O-CG 3.23Å; V502-L506 PolarHBondContact O-N 3.25Å
503S93.1Very high93.1Very high2 Ų253.5 Ų53.51%0.01427%0.266CS..Hα-helixtrans-66.1-36.2176.1-64.50000111.9D499 I500 K501 L506 N507 I530D499-S503 WeakPolarHBondContact O-CB 3.13Å; D499-S503 PolarHBondContact O-N 3.24Å; D499-S503 PolarHBondContact O-OG 2.95Å; I500-S503 WeakPolarHBondContact O-CA 3.36Å; I500-S503 WeakPolarHBondContact O-CB 3.32Å; I500-S503 PolarHBondContact O-N 3.4Å; K501-S503 VanDerWaalsContact C-N 3.3Å; K501-S503 PolarHBondContact O-N 3.17Å; S503-L506 PolarHBondContact O-N 3.37Å; S503-N507 PolarHBondContact O-N 3.42Å; S503-N507 PolarHBondContact O-ND2 3.37Å; S503-I530 PolarHBondContact OG-N 3.38Å; S503-I530 PolarHBondContact OG-O 3.45Å
504E92.5Very high92.7Very high109 Ų10954 Ų5451%0.50927%0.269SS..Hα-helixtrans-62-44.8175.8-69.3170.6177.800111.5I500 K501 V502 L506 N507 Q508I500-E504 PolarHBondContact O-N 2.95Å; K501-E504 WeakPolarHBondContact O-CB 3.5Å; K501-E504 PolarHBondContact O-N 3.43Å; K501-E504 VanDerWaalsContact O-N 3.17Å; V502-E504 VanDerWaalsContact C-N 3.33Å; E504-L506 PolarHBondContact O-N 3.02Å; E504-N507 WeakPolarHBondContact O-CB 3.32Å; E504-N507 PolarHBondContact O-N 3.19Å; E504-Q508 WeakPolarHBondContact O-CG 3.32Å; E504-Q508 PolarHBondContact O-N 3.34Å; E504-Q508 VanDerWaalsContact O-N 3.12Å
505D93.5Very high91.9Very high103 Ų10360.4 Ų60.455%0.55129%0.29SS*.Hα-helixtrans-61.5-44.2175.3-63.3-27.1000111.7K501 V502 N507 Q508 A509K501-D505 PolarHBondContact O-N 3.09Å; V502-D505 PolarHBondContact O-N 3Å; D505-N507 VanDerWaalsContact C-N 3.3Å; D505-N507 PolarHBondContact O-N 3.05Å; D505-Q508 PolarHBondContact O-N 2.81Å; D505-A509 PolarHBondContact O-N 3.45Å; D505-A509 VanDerWaalsContact O-N 3.08Å
506L92.8Very high91Very high26 Ų2663.4 Ų63.414%0.13631%0.312CS..Hα-helixtrans-63-36.6177.2-73172.1000112.2V502 S503 E504 A509 F510 I530 F561 Y562V502-L506 HydrophobicContact CG1-CD1 4.07Å; V502-L506 HydrophobicContact CG1-CG 4.45Å; V502-L506 WeakPolarHBondContact O-CG 3.23Å; V502-L506 PolarHBondContact O-N 3.25Å; S503-L506 PolarHBondContact O-N 3.37Å; E504-L506 PolarHBondContact O-N 3.02Å; L506-A509 PolarHBondContact O-N 3.4Å; L506-F510 WeakPolarHBondContact O-CB 3.38Å; L506-F510 PolarHBondContact O-N 2.8Å; L506-I530 HydrophobicContact CD1-CB 4.39Å; L506-I530 HydrophobicContact CD1-CD1 4.15Å; L506-F561 HydrophobicContact CD2-CE1 4.27Å; L506-F561 HydrophobicContact CD2-CZ 4.45Å; L506-F561 WeakPolarHBondContact O-CZ 3.46Å; L506-Y562 HydrophobicContact CD1-CE2 4.26Å
507N92.5Very high90Very high11 Ų1168 Ų686%0.05934%0.337CS..Hα-helixtrans-64.5-41.8174.8-84-71.3000112.2S503 E504 D505 F510 K511 N527 I528S503-N507 PolarHBondContact O-N 3.42Å; S503-N507 PolarHBondContact O-ND2 3.37Å; E504-N507 WeakPolarHBondContact O-CB 3.32Å; E504-N507 PolarHBondContact O-N 3.19Å; D505-N507 VanDerWaalsContact C-N 3.3Å; D505-N507 PolarHBondContact O-N 3.05Å; N507-F510 PolarHBondContact O-N 3.13Å; N507-K511 WeakPolarHBondContact O-CB 3.47Å; N507-K511 VanDerWaalsContact O-CG 3.25Å; N507-K511 WeakPolarHBondContact O-CG 3.34Å; N507-K511 PolarHBondContact O-N 3.37Å; N507-N527 PolarHBondContact ND2-OD1 2.87Å; N507-N527 WeakPolarHBondContact OD1-CA 3.03Å; N507-I528 PolarHBondContact ND2-O 3.2Å; N507-I528 PolarHBondContact OD1-N 3.48Å
508Q92.6Very high89Confident121 Ų12177.4 Ų77.457%0.56538%0.378SS*.Hα-helixtrans-61.8-48.4177.1-67.5176.92100110.5E504 D505 F510 K511 E512E504-Q508 WeakPolarHBondContact O-CG 3.32Å; E504-Q508 PolarHBondContact O-N 3.34Å; E504-Q508 VanDerWaalsContact O-N 3.12Å; D505-Q508 PolarHBondContact O-N 2.81Å; Q508-F510 VanDerWaalsContact C-N 3.34Å; Q508-F510 PolarHBondContact O-N 3.3Å; Q508-K511 PolarHBondContact O-N 3.15Å; Q508-E512 WeakPolarHBondContact O-CG 3.33Å; Q508-E512 PolarHBondContact O-N 3.11Å
509A91.9Very high88.2Confident39 Ų3974 Ų7432%0.32236%0.363SS..Hα-helixtrans-61.6-38.5177.100000113.1D505 L506 M513 F561D505-A509 PolarHBondContact O-N 3.45Å; D505-A509 VanDerWaalsContact O-N 3.08Å; L506-A509 PolarHBondContact O-N 3.4Å; A509-M513 WeakPolarHBondContact O-CB 3.44Å; A509-M513 PolarHBondContact O-N 2.94Å; A509-F561 HydrophobicContact CB-CE2 4.27Å; A509-F561 HydrophobicContact CB-CZ 3.98Å
510F91.4Very high87.4Confident0 Ų076.3 Ų76.30%038%0.382CS..Hα-helixtrans-64-46.3175.4-179.2-99.1000111.6L506 N507 Q508 E512 M513 H514 L519 I528 L554 V558 F561L506-F510 WeakPolarHBondContact O-CB 3.38Å; L506-F510 PolarHBondContact O-N 2.8Å; N507-F510 PolarHBondContact O-N 3.13Å; Q508-F510 VanDerWaalsContact C-N 3.34Å; Q508-F510 PolarHBondContact O-N 3.3Å; F510-E512 VanDerWaalsContact C-N 3.34Å; F510-E512 PolarHBondContact O-N 3.44Å; F510-M513 PolarHBondContact O-N 3.15Å; F510-H514 AromaticContact CD2-CD2 3.88Å; F510-H514 AromaticContact CE2-CD2 3.6Å; F510-H514 AromaticContact CE2-NE2 3.7Å; F510-H514 AromaticContact CZ-CD2 3.94Å; F510-H514 PolarHBondContact O-CD2 2.69Å; F510-H514 PolarHBondContact O-N 2.95Å; F510-H514 VanDerWaalsContact O-N 3.1Å; F510-L519 HydrophobicContact CE1-CD1 4.1Å; F510-L519 HydrophobicContact CZ-CD1 4.01Å; F510-I528 HydrophobicContact CB-CD1 4.5Å; F510-I528 HydrophobicContact CD1-CD1 3.83Å; F510-I528 HydrophobicContact CD2-CD1 4.16Å; F510-I528 HydrophobicContact CE1-CD1 4.05Å; F510-I528 HydrophobicContact CE2-CD1 4.37Å; F510-I528 HydrophobicContact CG-CD1 3.89Å; F510-I528 HydrophobicContact CZ-CD1 4.31Å; F510-L554 HydrophobicContact CZ-CD1 4.13Å; F510-V558 HydrophobicContact CE2-CG2 3.93Å; F510-V558 HydrophobicContact CZ-CG2 3.88Å; F510-F561 HydrophobicContact CB-CD1 4.36Å; F510-F561 HydrophobicContact CB-CD2 4.44Å; F510-F561 HydrophobicContact CB-CE1 4.01Å; F510-F561 HydrophobicContact CB-CE2 4.12Å; F510-F561 HydrophobicContact CB-CZ 3.89Å; F510-F561 HydrophobicContact CD2-CB 3.93Å; F510-F561 AromaticContact CD2-CD1 3.85Å; F510-F561 HydrophobicContact CD2-CD1 3.85Å; F510-F561 AromaticContact CD2-CD2 3.96Å; F510-F561 HydrophobicContact CD2-CD2 3.96Å; F510-F561 HydrophobicContact CD2-CE1 4.35Å; F510-F561 HydrophobicContact CD2-CE2 4.47Å; F510-F561 AromaticContact CD2-CG 3.64Å; F510-F561 HydrophobicContact CD2-CG 3.64Å; F510-F561 HydrophobicContact CE2-CB 4.2Å; F510-F561 HydrophobicContact CE2-CG 4.4Å
511K90.6Very high86.8Confident61 Ų6177.7 Ų77.727%0.26539%0.39SS..Hα-helixtrans-62-40.9178.1-72.8174.9-178.4-165.10112.2N507 Q508 H514 K515 A523 D524 V526N507-K511 WeakPolarHBondContact O-CB 3.47Å; N507-K511 VanDerWaalsContact O-CG 3.25Å; N507-K511 WeakPolarHBondContact O-CG 3.34Å; N507-K511 PolarHBondContact O-N 3.37Å; Q508-K511 PolarHBondContact O-N 3.15Å; K511-H514 PolarHBondContact O-N 3.33Å; K511-K515 PolarHBondContact O-N 2.88Å; K511-A523 WeakPolarHBondContact CE-O 3.19Å; K511-A523 HydrophobicContact CG-CB 4.34Å; K511-D524 PolarHBondContact NZ-O 2.93Å; K511-V526 WeakPolarHBondContact CE-O 3.16Å
512E89.1Confident86.4Confident148 Ų14877.4 Ų77.469%0.69240%0.397SS*.Hα-helixtrans-64.3-44.5176.1-73.5-178.9169.900112.3Q508 F510 H514 K515Q508-E512 WeakPolarHBondContact O-CG 3.33Å; Q508-E512 PolarHBondContact O-N 3.11Å; F510-E512 VanDerWaalsContact C-N 3.34Å; F510-E512 PolarHBondContact O-N 3.44Å; E512-H514 VanDerWaalsContact C-N 3.3Å; E512-H514 PolarHBondContact O-N 3.47Å; E512-K515 PolarHBondContact O-N 3.39Å
513M87.3Confident85.8Confident77 Ų7775.2 Ų75.238%0.37939%0.385SS..Hα-helixtrans-62-38.1179-173-177.2-59.100112.3A509 F510 F561A509-M513 WeakPolarHBondContact O-CB 3.44Å; A509-M513 PolarHBondContact O-N 2.94Å; F510-M513 PolarHBondContact O-N 3.15Å; M513-F561 HydrophobicContact CE-CD2 3.37Å; M513-F561 HydrophobicContact CE-CE2 3.66Å; M513-F561 HydrophobicContact SD-CD2 3.83Å
514H85.6Confident85.3Confident12 Ų1281.1 Ų81.16%0.05642%0.417CS..Hα-helixtrans-100.39.3-176.2-70.1-90.4000114.6F510 K511 E512 N516 N517 L519 A523 E557F510-H514 AromaticContact CD2-CD2 3.88Å; F510-H514 AromaticContact CE2-CD2 3.6Å; F510-H514 AromaticContact CE2-NE2 3.7Å; F510-H514 AromaticContact CZ-CD2 3.94Å; F510-H514 PolarHBondContact O-CD2 2.69Å; F510-H514 PolarHBondContact O-N 2.95Å; F510-H514 VanDerWaalsContact O-N 3.1Å; K511-H514 PolarHBondContact O-N 3.33Å; E512-H514 VanDerWaalsContact C-N 3.3Å; E512-H514 PolarHBondContact O-N 3.47Å; H514-N516 PolarHBondContact O-N 3.32Å; H514-N516 VanDerWaalsContact O-N 3.12Å; H514-N517 HydrophobicContact CB-CB 4.43Å; H514-N517 PolarHBondContact O-N 2.87Å; H514-N517 VanDerWaalsContact O-N 3.12Å; H514-L519 HydrophobicContact CB-CD1 3.56Å; H514-L519 HydrophobicContact CB-CG 4.08Å; H514-A523 HydrophobicContact CB-CB 4.18Å; H514-E557 IonicContact CE1-OE2 3.09Å; H514-E557 PolarHBondContact CE1-OE2 3.36Å
515K79.7Confident85.1Confident173 Ų17379.9 Ų79.975%0.75242%0.42SS*.THydrogen-bonded Turntrans-55.1-34-179.9-170.8174.6-178.8176.20113.7K511 E512K511-K515 PolarHBondContact O-N 2.88Å; E512-K515 PolarHBondContact O-N 3.39Å
516N76.6Confident84.8Confident151 Ų15175.7 Ų75.781%0.80740%0.399SS*.THydrogen-bonded Turntrans-106.8-5.5-179.3-63.1-25.1000113.4H514H514-N516 PolarHBondContact O-N 3.32Å; H514-N516 VanDerWaalsContact O-N 3.12Å
517N73.7Confident84.8Confident97 Ų9779.8 Ų79.852%0.51942%0.421SS..SBendtrans-90.6141.8-178.1-74.4-12.5000110.3H514 L519H514-N517 HydrophobicContact CB-CB 4.43Å; H514-N517 PolarHBondContact O-N 2.87Å; H514-N517 VanDerWaalsContact O-N 3.12Å; N517-L519 PolarHBondContact O-N 2.88Å
518K73.4Confident84.7Confident216 Ų21680.4 Ų80.494%0.93942%0.423SS*.  trans-79.984.4173.6-70.7-175.9178.2-178.80109.6
519L79.4Confident84.7Confident30 Ų3077.6 Ų77.616%0.15741%0.41CS..  trans-72.4157.9162.6-71.8176.4000110.3F510 H514 N517 L521 A523 L554 E557F510-L519 HydrophobicContact CE1-CD1 4.1Å; F510-L519 HydrophobicContact CZ-CD1 4.01Å; H514-L519 HydrophobicContact CB-CD1 3.56Å; H514-L519 HydrophobicContact CB-CG 4.08Å; N517-L519 PolarHBondContact O-N 2.88Å; L519-L521 WeakPolarHBondContact CB-O 3.47Å; L519-L521 PolarHBondContact O-N 3.42Å; L519-A523 HydrophobicContact CD1-CB 4.11Å; L519-L554 HydrophobicContact CD1-CD1 4.4Å; L519-E557 HydrophobicContact CD2-CB 3.99Å; L519-E557 HydrophobicContact CD2-CG 3.69Å
520A78.4Confident84.7Confident52 Ų5277 Ų7743%0.4340%0.401SS..SBendtrans-61.5-28.7173.300000112.7E550 D553A520-E550 HydrophobicContact CB-CB 4.44Å; A520-D553 HydrophobicContact CB-CB 3.97Å
521L82Confident84.8Confident49 Ų4979.5 Ų79.526%0.25741%0.413SS..SBendtrans-123.1146.7174.2-67.7171.6000110.4L519 A523 V526 E550 L551 L554L519-L521 WeakPolarHBondContact CB-O 3.47Å; L519-L521 PolarHBondContact O-N 3.42Å; L521-A523 PolarHBondContact O-N 3.2Å; L521-V526 HydrophobicContact CB-CG2 4.23Å; L521-E550 HydrophobicContact CD1-CB 4.47Å; L521-E550 HydrophobicContact CD2-CB 4.2Å; L521-E550 HydrophobicContact CG-CB 4.16Å; L521-L551 HydrophobicContact CD1-CD2 3.71Å; L521-L554 HydrophobicContact CD1-CD2 4.4Å
522P83.8Confident84.8Confident90 Ų9080.2 Ų80.258%0.58442%0.42SS*.  trans-54.3129.5172-23.333.1000110.8D524 S525P522-D524 PolarHBondContact O-N 3.28Å; P522-S525 PolarHBondContact O-N 2.89Å; P522-S525 PolarHBondContact O-OG 3.1Å
523A81.2Confident84.8Confident12 Ų1276.1 Ų76.110%0.09941%0.412CS..G310 helixtrans-54.9-33.3-178.500000112.1K511 H514 L519 L521 S525 V526K511-A523 WeakPolarHBondContact CE-O 3.19Å; K511-A523 HydrophobicContact CG-CB 4.34Å; H514-A523 HydrophobicContact CB-CB 4.18Å; L519-A523 HydrophobicContact CD1-CB 4.11Å; L521-A523 PolarHBondContact O-N 3.2Å; A523-S525 VanDerWaalsContact C-N 3.29Å; A523-S525 PolarHBondContact O-N 3.43Å; A523-V526 PolarHBondContact O-N 3Å
524D84.4Confident84.7Confident127 Ų12775 Ų7568%0.67942%0.42SS*.G310 helixtrans-66-25.7178.2-71.9-31.7000114.5K511 P522 V526K511-D524 PolarHBondContact NZ-O 2.93Å; P522-D524 PolarHBondContact O-N 3.28Å; D524-V526 VanDerWaalsContact C-N 3.3Å
525S86.7Confident85Confident83 Ų8374.6 Ų74.658%0.5842%0.419SS*.G310 helixtrans-85.8-3.1178.267.50000113.5P522 A523P522-S525 PolarHBondContact O-N 2.89Å; P522-S525 PolarHBondContact O-OG 3.1Å; A523-S525 VanDerWaalsContact C-N 3.29Å; A523-S525 PolarHBondContact O-N 3.43Å
526V88.7Confident85.4Confident15 Ų1567 Ų679%0.09139%0.385CS..  trans-100.9133.4179.8-1800000109.6K511 L521 A523 D524 I528 L554K511-V526 WeakPolarHBondContact CE-O 3.16Å; L521-V526 HydrophobicContact CB-CG2 4.23Å; A523-V526 PolarHBondContact O-N 3Å; D524-V526 VanDerWaalsContact C-N 3.3Å; V526-I528 HydrophobicContact CG1-CD1 4.17Å; V526-I528 HydrophobicContact CG1-CG1 3.75Å; V526-L554 HydrophobicContact CB-CD2 4.34Å; V526-L554 HydrophobicContact CG1-CD2 3.73Å; V526-L554 HydrophobicContact CG2-CD1 4.22Å; V526-L554 HydrophobicContact CG2-CD2 3.6Å
527N91.2Very high84.9Confident112 Ų11262.5 Ų62.560%0.59937%0.366SS*.  trans-130.9112.5172.5-174.9-13.1000109.5N507N507-N527 PolarHBondContact ND2-OD1 2.87Å; N507-N527 WeakPolarHBondContact OD1-CA 3.03Å
528I91.9Very high84.2Confident23 Ų2368.2 Ų68.212%0.11838%0.38CS..  trans-103.5122.3-173.3-52.9160.8000108.6N507 F510 V526 I530 V558N507-I528 PolarHBondContact ND2-O 3.2Å; N507-I528 PolarHBondContact OD1-N 3.48Å; F510-I528 HydrophobicContact CB-CD1 4.5Å; F510-I528 HydrophobicContact CD1-CD1 3.83Å; F510-I528 HydrophobicContact CD2-CD1 4.16Å; F510-I528 HydrophobicContact CE1-CD1 4.05Å; F510-I528 HydrophobicContact CE2-CD1 4.37Å; F510-I528 HydrophobicContact CG-CD1 3.89Å; F510-I528 HydrophobicContact CZ-CD1 4.31Å; V526-I528 HydrophobicContact CG1-CD1 4.17Å; V526-I528 HydrophobicContact CG1-CG1 3.75Å; I528-I530 HydrophobicContact CG2-CD1 4.17Å; I528-I530 HydrophobicContact CG2-CG1 3.78Å; I528-V558 HydrophobicContact CD1-CB 4.29Å; I528-V558 HydrophobicContact CD1-CG1 3.83Å; I528-V558 HydrophobicContact CD1-CG2 3.48Å; I528-V558 VanDerWaalsContact CD1-CG2 3.48Å; I528-V558 HydrophobicContact CG1-CG1 4.4Å; I528-V558 HydrophobicContact CG1-CG2 4.21Å; I528-V558 HydrophobicContact CG2-CG1 3.95Å
529K92.2Very high83.4Confident63 Ų6360.5 Ų60.527%0.27435%0.353SS..  trans-108109.7174.6-66.7-172.9174.6-175.10109.7L462 I463 I500 L531L462-K529 PolarHBondContact O-NZ 3.26Å; I463-K529 HydrophobicContact CD1-CD 4.18Å; I463-K529 PolarHBondContact O-NZ 3.21Å; I500-K529 HydrophobicContact CD1-CD 4.15Å; K529-L531 HydrophobicContact CB-CD2 4.16Å; K529-L531 HydrophobicContact CB-CG 4.34Å
530I92.3Very high82.3Confident26 Ų2664 Ų6413%0.13338%0.38CS..  trans-102.5111.5-179.6-55-170.5000108.9S503 L506 I528 Y562 L571S503-I530 PolarHBondContact OG-N 3.38Å; S503-I530 PolarHBondContact OG-O 3.45Å; L506-I530 HydrophobicContact CD1-CB 4.39Å; L506-I530 HydrophobicContact CD1-CD1 4.15Å; I528-I530 HydrophobicContact CG2-CD1 4.17Å; I528-I530 HydrophobicContact CG2-CG1 3.78Å; I530-Y562 HydrophobicContact CB-CE2 4.46Å; I530-Y562 HydrophobicContact CD1-CD2 3.22Å; I530-Y562 HydrophobicContact CD1-CE2 3.52Å; I530-Y562 HydrophobicContact CD1-CG 4.01Å; I530-Y562 HydrophobicContact CG2-CD2 4.43Å; I530-Y562 HydrophobicContact CG2-CE2 3.72Å; I530-L571 HydrophobicContact CG2-CD2 3.99Å
531L92.3Very high81.7Confident52 Ų5266.5 Ų66.527%0.27238%0.383SS..  trans-119.6143.4-163.1-52.4177.2000111.6I463 D499 I500 K529 A533 W536I463-L531 HydrophobicContact CD1-CD1 3.49Å; I463-L531 VanDerWaalsContact CD1-CD1 3.49Å; D499-L531 HydrophobicContact CB-CD2 4.17Å; I500-L531 HydrophobicContact CD1-CD2 4.16Å; K529-L531 HydrophobicContact CB-CD2 4.16Å; K529-L531 HydrophobicContact CB-CG 4.34Å; L531-A533 PolarHBondContact O-N 3.23Å; L531-W536 HydrophobicContact CB-CD2 4.21Å; L531-W536 HydrophobicContact CB-CG 4.02Å; L531-W536 HydrophobicContact CD1-CD2 3.83Å; L531-W536 HydrophobicContact CD1-CE3 3.92Å; L531-W536 HydrophobicContact CD1-CG 4.36Å; L531-W536 HydrophobicContact CD1-CH2 4.29Å; L531-W536 HydrophobicContact CD1-CZ2 4.21Å; L531-W536 HydrophobicContact CD1-CZ3 4.15Å; L531-W536 HydrophobicContact CD2-CD2 4.45Å; L531-W536 HydrophobicContact CD2-CH2 4.31Å; L531-W536 HydrophobicContact CD2-CZ2 3.67Å; L531-W536 HydrophobicContact CG-CD2 4.38Å; L531-W536 HydrophobicContact CG-CZ2 4.43Å
532N91.5Very high81.2Confident76 Ų7671.9 Ų71.941%0.40640%0.404SS..  trans-74.4116.6176.5-174.5-53.3000110.7D499 G534 A535 W536D499-N532 WeakPolarHBondContact OD2-CB 3.45Å; D499-N532 PolarHBondContact OD2-N 3.03Å; N532-G534 PolarHBondContact O-N 3.44Å; N532-G534 VanDerWaalsContact O-N 3.1Å; N532-G534 WeakPolarHBondContact OD1-CA 3.38Å; N532-G534 PolarHBondContact OD1-N 3.21Å; N532-A535 HydrophobicContact CB-CB 4.26Å; N532-A535 PolarHBondContact O-N 2.8Å; N532-A535 PolarHBondContact OD1-N 3.05Å; N532-W536 PolarHBondContact O-N 3.05Å; N532-W536 VanDerWaalsContact O-N 3.08Å
533A87.8Confident81Confident62 Ų6268.9 Ų68.951%0.51239%0.385SS..Hα-helixtrans-56-30.8-179.700000114.1L531 S537L531-A533 PolarHBondContact O-N 3.23Å; A533-S537 PolarHBondContact O-N 3.11Å
534G87.1Confident81.2Confident53 Ų5374.1 Ų74.155%0.54641%0.405SS..Hα-helixtrans-71.3-34.1176.900000113.6N532N532-G534 PolarHBondContact O-N 3.44Å; N532-G534 VanDerWaalsContact O-N 3.1Å; N532-G534 WeakPolarHBondContact OD1-CA 3.38Å; N532-G534 PolarHBondContact OD1-N 3.21Å
535A90.4Very high81.5Confident4 Ų469 Ų693%0.03338%0.378CS..Hα-helixtrans-81-43.617900000112K455 R495 M496 N532K455-A535 WeakPolarHBondContact CE-O 3.42Å; K455-A535 PolarHBondContact NZ-O 3.05Å; R495-A535 HydrophobicContact CB-CB 3.93Å; R495-A535 HydrophobicContact CG-CB 3.74Å; M496-A535 HydrophobicContact CG-CB 4.28Å; N532-A535 HydrophobicContact CB-CB 4.26Å; N532-A535 PolarHBondContact O-N 2.8Å; N532-A535 PolarHBondContact OD1-N 3.05Å
536W87.7Confident81.7Confident15 Ų1566.5 Ų66.56%0.05736%0.361CS..Hα-helixtrans-85.5-12.8-173.1-68.175.3000114.5T459 L462 I463 M496 D499 I500 L531 N532 M577T459-W536 HydrophobicContact CG2-CE3 3.76Å; T459-W536 HydrophobicContact CG2-CZ3 3.85Å; L462-W536 HydrophobicContact CB-CH2 3.73Å; L462-W536 HydrophobicContact CB-CZ3 4.39Å; L462-W536 HydrophobicContact CD1-CH2 3.85Å; L462-W536 HydrophobicContact CD1-CZ2 4.24Å; L462-W536 HydrophobicContact CG-CH2 4.47Å; I463-W536 HydrophobicContact CD1-CE3 4.39Å; I463-W536 HydrophobicContact CD1-CH2 4.07Å; I463-W536 HydrophobicContact CD1-CZ3 3.71Å; I463-W536 HydrophobicContact CG1-CH2 4.31Å; I463-W536 HydrophobicContact CG1-CZ3 3.71Å; M496-W536 HydrophobicContact CB-CD2 4.48Å; M496-W536 HydrophobicContact CB-CH2 4.41Å; M496-W536 HydrophobicContact CB-CZ2 3.71Å; M496-W536 HydrophobicContact CE-CD2 3.98Å; M496-W536 HydrophobicContact CE-CE3 3.71Å; M496-W536 HydrophobicContact CE-CH2 4.04Å; M496-W536 HydrophobicContact CE-CZ2 4.29Å; M496-W536 HydrophobicContact CE-CZ3 3.74Å; M496-W536 HydrophobicContact CG-CD2 3.93Å; M496-W536 HydrophobicContact CG-CG 4.13Å; M496-W536 HydrophobicContact CG-CZ2 4.09Å; D499-W536 PolarHBondContact OD2-NE1 3.42Å; D499-W536 VanDerWaalsContact OD2-NE1 3.13Å; I500-W536 HydrophobicContact CD1-CH2 3.85Å; I500-W536 HydrophobicContact CD1-CZ2 3.9Å; I500-W536 HydrophobicContact CG1-CH2 4.18Å; I500-W536 HydrophobicContact CG1-CZ2 4Å; L531-W536 HydrophobicContact CB-CD2 4.21Å; L531-W536 HydrophobicContact CB-CG 4.02Å; L531-W536 HydrophobicContact CD1-CD2 3.83Å; L531-W536 HydrophobicContact CD1-CE3 3.92Å; L531-W536 HydrophobicContact CD1-CG 4.36Å; L531-W536 HydrophobicContact CD1-CH2 4.29Å; L531-W536 HydrophobicContact CD1-CZ2 4.21Å; L531-W536 HydrophobicContact CD1-CZ3 4.15Å; L531-W536 HydrophobicContact CD2-CD2 4.45Å; L531-W536 HydrophobicContact CD2-CH2 4.31Å; L531-W536 HydrophobicContact CD2-CZ2 3.67Å; L531-W536 HydrophobicContact CG-CD2 4.38Å; L531-W536 HydrophobicContact CG-CZ2 4.43Å; N532-W536 PolarHBondContact O-N 3.05Å; N532-W536 VanDerWaalsContact O-N 3.08Å; W536-M577 HydrophobicContact CE3-CE 4.36Å
537S67.7Low81.8Confident56 Ų5666.7 Ų66.739%0.39236%0.362SS..  trans70.9151.2-175.388.90000115A533A533-S537 PolarHBondContact O-N 3.11Å
538R59.1Low81.8Confident216 Ų21662.1 Ų62.182%0.81534%0.338SS*.  trans-83.6115.6-175.9-55.7178.8-168.1-129.62.7108.9S540R538-S540 PolarHBondContact O-N 3.13Å
539S56.4Low81.6Confident54 Ų5465.2 Ų65.238%0.37836%0.358SS..  trans-64.5115.2151.556.90000106.3E541 H574S539-E541 PolarHBondContact O-N 2.79Å; S539-H574 PolarHBondContact OG-CE1 3.48Å; S539-H574 PolarHBondContact OG-ND1 3.49Å
540S56.5Low81.3Confident105 Ų10566.2 Ų66.273%0.73436%0.363SS*.SBendtrans-68.5-15-170.542.20000113.9R538R538-S540 PolarHBondContact O-N 3.13Å
541E64Low81.2Confident104 Ų10467.3 Ų67.349%0.48637%0.369SS..SBendtrans-117.4121.3-175.6-155.7165.7-156.400111.4S539 V543 R698S539-E541 PolarHBondContact O-N 2.79Å; E541-V543 PolarHBondContact O-N 3.31Å; E541-R698 IonicContact OE1-NH2 3.43Å; E541-R698 IonicContact OE2-CZ 3.9Å; E541-R698 VanDerWaalsContact OE2-CZ 3.24Å; E541-R698 IonicContact OE2-NH1 2.66Å; E541-R698 PolarHBondContact OE2-NH1 3.15Å; E541-R698 IonicContact OE2-NH2 3.72Å; E541-R698 PolarHBondContact OE2-NH2 3.32Å
542K71.7Confident81.1Confident161 Ų16169.2 Ų69.270%0.738%0.377SS*.  trans-73.7109.7169.4-174.9-177179-172.10107.3F544K542-F544 HydrophobicContact CD-CE1 4.33Å; K542-F544 HydrophobicContact CD-CZ 4.33Å
543V80.1Confident81.1Confident28 Ų2869.7 Ų69.717%0.1738%0.38CS..  trans-83.5119172.2-1770000108.2E541 F598 L625 P626 E629E541-V543 PolarHBondContact O-N 3.31Å; V543-F598 HydrophobicContact CB-CZ 3.96Å; V543-F598 HydrophobicContact CG1-CE1 4.21Å; V543-F598 HydrophobicContact CG1-CE2 4.13Å; V543-F598 HydrophobicContact CG1-CZ 3.53Å; V543-L625 HydrophobicContact CG1-CD2 4.31Å; V543-P626 HydrophobicContact CG1-CG 4Å; V543-E629 HydrophobicContact CG1-CG 4.22Å
544F85.2Confident81.2Confident122 Ų12267.6 Ų67.654%0.53536%0.36SS..  trans-74.1141.2172.8-64.8-86.9000109.9K542K542-F544 HydrophobicContact CD-CE1 4.33Å; K542-F544 HydrophobicContact CD-CZ 4.33Å
545V90.1Very high81.4Confident18 Ų1866.7 Ų66.711%0.10934%0.342CS..  trans-155.7133.6175.659.50000108.5L547 H575 F598 A601 T623 L625V545-L547 HydrophobicContact CG1-CD2 3.95Å; V545-H575 HydrophobicContact CG1-CB 3.86Å; V545-F598 HydrophobicContact CB-CD1 4.34Å; V545-F598 HydrophobicContact CB-CE1 4.18Å; V545-F598 HydrophobicContact CG1-CD1 4.44Å; V545-F598 HydrophobicContact CG1-CE1 4.08Å; V545-F598 HydrophobicContact CG2-CD1 4.16Å; V545-A601 HydrophobicContact CG2-CB 3.76Å; V545-T623 WeakPolarHBondContact CA-O 3.4Å; V545-L625 HydrophobicContact CB-CD2 3.89Å; V545-L625 HydrophobicContact CG2-CD2 3.87Å; V545-L625 HydrophobicContact CG2-CG 4.18Å
546S92.5Very high81.4Confident32 Ų3269.8 Ų69.822%0.22436%0.362CS..PPolyproline II helixtrans-79.3122.6169.3-53.90000108.9T623 E624S546-T623 PolarHBondContact N-O 2.96Å; S546-E624 VanDerWaalsContact OG-CG 3.29Å; S546-E624 WeakPolarHBondContact OG-CG 3.39Å
547L91.1Very high81.6Confident19 Ų1972.5 Ų72.510%0.09938%0.375CS..PPolyproline II helixtrans-93.7157.5-178.5-59.9175.5000109.7V545 L551 E552 I555 T597V545-L547 HydrophobicContact CG1-CD2 3.95Å; L547-L551 HydrophobicContact CB-CB 4.28Å; L547-L551 HydrophobicContact CD1-CB 4.47Å; L547-E552 HydrophobicContact CB-CG 3.7Å; L547-E552 PolarHBondContact N-OE1 2.95Å; L547-I555 HydrophobicContact CD1-CD1 3.72Å; L547-T597 HydrophobicContact CD2-CG2 3.46Å; L547-T597 VanDerWaalsContact CD2-CG2 3.46Å
548P89.4Confident82.7Confident15 Ų1569.9 Ų69.910%0.09736%0.357CS..PPolyproline II helixtrans-58.8146165.8-25.837.4000111.7E550 L551 E552 L600 F604P548-E550 WeakPolarHBondContact CB-OE2 3.47Å; P548-E550 PolarHBondContact O-N 3.05Å; P548-E550 VanDerWaalsContact O-N 3.11Å; P548-L551 PolarHBondContact O-N 2.8Å; P548-E552 PolarHBondContact O-N 3.41Å; P548-L600 HydrophobicContact CG-CD2 3.4Å; P548-L600 VanDerWaalsContact CG-CD2 3.4Å; P548-F604 HydrophobicContact CB-CD1 3.44Å; P548-F604 VanDerWaalsContact CB-CD1 3.44Å; P548-F604 HydrophobicContact CB-CE1 3.6Å; P548-F604 HydrophobicContact CB-CG 4.23Å; P548-F604 HydrophobicContact CB-CZ 4.49Å; P548-F604 HydrophobicContact CG-CB 4.05Å; P548-F604 HydrophobicContact CG-CD1 3.31Å; P548-F604 HydrophobicContact CG-CD2 4.19Å; P548-F604 HydrophobicContact CG-CE1 3.7Å; P548-F604 HydrophobicContact CG-CG 3.59Å; P548-F604 HydrophobicContact CG-CZ 4.28Å
549T88.3Confident84.3Confident88 Ų8863.5 Ų63.554%0.5434%0.336SS..Hα-helixtrans-50.4-40.2-177.7-50.10000112.3L551 E552 D553T549-L551 PolarHBondContact O-N 2.91Å; T549-E552 PolarHBondContact O-N 3.3Å; T549-E552 VanDerWaalsContact O-N 3.15Å; T549-D553 WeakPolarHBondContact O-CB 3.15Å; T549-D553 VanDerWaalsContact O-CG 3.29Å; T549-D553 PolarHBondContact O-N 3.46Å
550E86.7Confident85.9Confident84 Ų8467.5 Ų67.539%0.39335%0.349SS..Hα-helixtrans-63.8-28.5-179.5-55.288.716200113.3A520 L521 P548A520-E550 HydrophobicContact CB-CB 4.44Å; L521-E550 HydrophobicContact CD1-CB 4.47Å; L521-E550 HydrophobicContact CD2-CB 4.2Å; L521-E550 HydrophobicContact CG-CB 4.16Å; P548-E550 WeakPolarHBondContact CB-OE2 3.47Å; P548-E550 PolarHBondContact O-N 3.05Å; P548-E550 VanDerWaalsContact O-N 3.11Å
551L89.7Confident87.5Confident49 Ų4962.9 Ų62.926%0.25732%0.315SS..Hα-helixtrans-85.7-35.3173.8-66.1-177.2000111.9L521 L547 P548 T549 D553 L554 I555 L600L521-L551 HydrophobicContact CD1-CD2 3.71Å; L547-L551 HydrophobicContact CB-CB 4.28Å; L547-L551 HydrophobicContact CD1-CB 4.47Å; P548-L551 PolarHBondContact O-N 2.8Å; T549-L551 PolarHBondContact O-N 2.91Å; L551-D553 VanDerWaalsContact C-N 3.35Å; L551-L554 PolarHBondContact O-N 3.38Å; L551-I555 PolarHBondContact O-N 3.15Å; L551-L600 HydrophobicContact CD1-CD1 4.49Å; L551-L600 HydrophobicContact CD1-CD2 4.05Å
552E90.2Very high88.9Confident92 Ų9258.8 Ų58.843%0.4330%0.296SS..Hα-helixtrans-62.8-42.3175.2-66.1-170.2159.100111.6L547 P548 T549 L554 I555 P556L547-E552 HydrophobicContact CB-CG 3.7Å; L547-E552 PolarHBondContact N-OE1 2.95Å; P548-E552 PolarHBondContact O-N 3.41Å; T549-E552 PolarHBondContact O-N 3.3Å; T549-E552 VanDerWaalsContact O-N 3.15Å; E552-L554 PolarHBondContact O-N 3.3Å; E552-I555 PolarHBondContact O-N 3.29Å; E552-P556 WeakPolarHBondContact O-CD 3.48Å
553D90.7Very high89.9Confident87 Ų8759 Ų5947%0.46530%0.296SS..THydrogen-bonded Turntrans-65.9-26.5177.6-71-17.5000112.5A520 T549 L551 P556A520-D553 HydrophobicContact CB-CB 3.97Å; T549-D553 WeakPolarHBondContact O-CB 3.15Å; T549-D553 VanDerWaalsContact O-CG 3.29Å; T549-D553 PolarHBondContact O-N 3.46Å; L551-D553 VanDerWaalsContact C-N 3.35Å; D553-P556 WeakPolarHBondContact O-CD 3.47Å; D553-P556 WeakPolarHBondContact O-CG 3.27Å
554L90.1Very high90.3Very high18 Ų1865.2 Ų65.29%0.09432%0.321CS..Hα-helixtrans-78.1-32179.8-179.267.2000112.8F510 L519 L521 V526 L551 E552 E557 V558F510-L554 HydrophobicContact CZ-CD1 4.13Å; L519-L554 HydrophobicContact CD1-CD1 4.4Å; L521-L554 HydrophobicContact CD1-CD2 4.4Å; V526-L554 HydrophobicContact CB-CD2 4.34Å; V526-L554 HydrophobicContact CG1-CD2 3.73Å; V526-L554 HydrophobicContact CG2-CD1 4.22Å; V526-L554 HydrophobicContact CG2-CD2 3.6Å; L551-L554 PolarHBondContact O-N 3.38Å; E552-L554 PolarHBondContact O-N 3.3Å; L554-E557 PolarHBondContact O-N 3.42Å; L554-V558 HydrophobicContact CD1-CG2 4.27Å; L554-V558 HydrophobicContact CG-CG2 4.18Å; L554-V558 WeakPolarHBondContact O-CG2 3.34Å; L554-V558 PolarHBondContact O-N 3.46Å; L554-V558 VanDerWaalsContact O-N 3.14Å
555I91.4Very high90.4Very high34 Ų3463 Ų6317%0.17432%0.315CS..Hα-helixtrans-54-53.7-178.4-74.3170.6000113L547 L551 E552 E557 V558 E559 W573L547-I555 HydrophobicContact CD1-CD1 3.72Å; L551-I555 PolarHBondContact O-N 3.15Å; E552-I555 PolarHBondContact O-N 3.29Å; I555-E557 VanDerWaalsContact C-N 3.31Å; I555-E557 PolarHBondContact O-N 3.08Å; I555-V558 PolarHBondContact O-N 2.93Å; I555-E559 HydrophobicContact CG2-CG 4.43Å; I555-E559 WeakPolarHBondContact O-CG 3.36Å; I555-E559 PolarHBondContact O-N 3.32Å; I555-W573 HydrophobicContact CB-CZ2 4.07Å; I555-W573 HydrophobicContact CG1-CD2 4.25Å; I555-W573 HydrophobicContact CG1-CE3 4.49Å; I555-W573 HydrophobicContact CG1-CH2 4.11Å; I555-W573 HydrophobicContact CG1-CZ2 3.86Å; I555-W573 HydrophobicContact CG1-CZ3 4.43Å; I555-W573 HydrophobicContact CG2-CZ2 3.87Å
556P91.8Very high90.4Very high69 Ų6964.6 Ų64.645%0.44832%0.321SS..Hα-helixtrans-63.3-35.9-177.723.7-33.4000112.7E552 D553 V558 E559 E560E552-P556 WeakPolarHBondContact O-CD 3.48Å; D553-P556 WeakPolarHBondContact O-CD 3.47Å; D553-P556 WeakPolarHBondContact O-CG 3.27Å; P556-V558 VanDerWaalsContact C-N 3.35Å; P556-V558 PolarHBondContact O-N 3.13Å; P556-E559 PolarHBondContact O-N 2.87Å; P556-E560 WeakPolarHBondContact O-CB 3.44Å; P556-E560 PolarHBondContact O-N 2.91Å
557E90.4Very high90.1Very high72 Ų7268.4 Ų68.434%0.33635%0.348SS..Hα-helixtrans-61.8-42.9176.7-62.1-70154.800111.4H514 L519 L554 I555 F561H514-E557 IonicContact CE1-OE2 3.09Å; H514-E557 PolarHBondContact CE1-OE2 3.36Å; L519-E557 HydrophobicContact CD2-CB 3.99Å; L519-E557 HydrophobicContact CD2-CG 3.69Å; L554-E557 PolarHBondContact O-N 3.42Å; I555-E557 VanDerWaalsContact C-N 3.31Å; I555-E557 PolarHBondContact O-N 3.08Å; E557-F561 WeakPolarHBondContact O-CB 3.34Å; E557-F561 PolarHBondContact O-N 3.24Å
558V91Very high90.1Very high1 Ų171.9 Ų71.91%0.00639%0.388CS..Hα-helixtrans-67.5-40.9176173.80000111.7F510 I528 L554 I555 P556 Y562 W573F510-V558 HydrophobicContact CE2-CG2 3.93Å; F510-V558 HydrophobicContact CZ-CG2 3.88Å; I528-V558 HydrophobicContact CD1-CB 4.29Å; I528-V558 HydrophobicContact CD1-CG1 3.83Å; I528-V558 HydrophobicContact CD1-CG2 3.48Å; I528-V558 VanDerWaalsContact CD1-CG2 3.48Å; I528-V558 HydrophobicContact CG1-CG1 4.4Å; I528-V558 HydrophobicContact CG1-CG2 4.21Å; I528-V558 HydrophobicContact CG2-CG1 3.95Å; L554-V558 HydrophobicContact CD1-CG2 4.27Å; L554-V558 HydrophobicContact CG-CG2 4.18Å; L554-V558 WeakPolarHBondContact O-CG2 3.34Å; L554-V558 PolarHBondContact O-N 3.46Å; L554-V558 VanDerWaalsContact O-N 3.14Å; I555-V558 PolarHBondContact O-N 2.93Å; P556-V558 VanDerWaalsContact C-N 3.35Å; P556-V558 PolarHBondContact O-N 3.13Å; V558-Y562 WeakPolarHBondContact O-CB 2.93Å; V558-Y562 PolarHBondContact O-N 3.3Å; V558-W573 HydrophobicContact CB-CH2 4.01Å; V558-W573 HydrophobicContact CB-CZ2 4.09Å; V558-W573 HydrophobicContact CG1-CH2 3.84Å; V558-W573 HydrophobicContact CG1-CZ2 4.02Å; V558-W573 HydrophobicContact CG2-CH2 4.37Å
559E92.5Very high90.1Very high81 Ų8178.5 Ų78.538%0.37941%0.411SS..Hα-helixtrans-65.8-40.6178.1-71.1-171.5174.700112.2I555 P556 Y562 K563 L571 W573I555-E559 HydrophobicContact CG2-CG 4.43Å; I555-E559 WeakPolarHBondContact O-CG 3.36Å; I555-E559 PolarHBondContact O-N 3.32Å; P556-E559 PolarHBondContact O-N 2.87Å; E559-Y562 PolarHBondContact O-N 3.44Å; E559-K563 VanDerWaalsContact O-CB 3.24Å; E559-K563 WeakPolarHBondContact O-CB 3.44Å; E559-K563 PolarHBondContact O-N 2.79Å; E559-L571 HydrophobicContact CG-CD1 4.16Å; E559-W573 HydrophobicContact CG-CZ2 4.38Å; E559-W573 PolarHBondContact OE1-NE1 3.35Å
560E90.9Very high90.1Very high138 Ų13882.3 Ų82.365%0.64542%0.42SS*.Hα-helixtrans-65.7-47.2175.8-175.3170-179.900111.5P556 Y562 K563 K564P556-E560 WeakPolarHBondContact O-CB 3.44Å; P556-E560 PolarHBondContact O-N 2.91Å; E560-Y562 VanDerWaalsContact C-N 3.3Å; E560-Y562 PolarHBondContact O-N 3.28Å; E560-K563 PolarHBondContact O-N 2.87Å; E560-K564 PolarHBondContact O-N 3.46Å
561F90.8Very high90.2Very high8 Ų880.3 Ų80.34%0.03541%0.412CS..Hα-helixtrans-52.1-49.6173.2166.6-99.8000111.4L506 A509 F510 M513 E557 K564 N565L506-F561 HydrophobicContact CD2-CE1 4.27Å; L506-F561 HydrophobicContact CD2-CZ 4.45Å; L506-F561 WeakPolarHBondContact O-CZ 3.46Å; A509-F561 HydrophobicContact CB-CE2 4.27Å; A509-F561 HydrophobicContact CB-CZ 3.98Å; F510-F561 HydrophobicContact CB-CD1 4.36Å; F510-F561 HydrophobicContact CB-CD2 4.44Å; F510-F561 HydrophobicContact CB-CE1 4.01Å; F510-F561 HydrophobicContact CB-CE2 4.12Å; F510-F561 HydrophobicContact CB-CZ 3.89Å; F510-F561 HydrophobicContact CD2-CB 3.93Å; F510-F561 AromaticContact CD2-CD1 3.85Å; F510-F561 HydrophobicContact CD2-CD1 3.85Å; F510-F561 AromaticContact CD2-CD2 3.96Å; F510-F561 HydrophobicContact CD2-CD2 3.96Å; F510-F561 HydrophobicContact CD2-CE1 4.35Å; F510-F561 HydrophobicContact CD2-CE2 4.47Å; F510-F561 AromaticContact CD2-CG 3.64Å; F510-F561 HydrophobicContact CD2-CG 3.64Å; F510-F561 HydrophobicContact CE2-CB 4.2Å; F510-F561 HydrophobicContact CE2-CG 4.4Å; M513-F561 HydrophobicContact CE-CD2 3.37Å; M513-F561 HydrophobicContact CE-CE2 3.66Å; M513-F561 HydrophobicContact SD-CD2 3.83Å; E557-F561 WeakPolarHBondContact O-CB 3.34Å; E557-F561 PolarHBondContact O-N 3.24Å; F561-K564 PolarHBondContact O-N 3.44Å; F561-N565 WeakPolarHBondContact CE2-ND2 3.24Å; F561-N565 PolarHBondContact O-N 2.81Å; F561-N565 PolarHBondContact O-ND2 3.11Å
562Y92.4Very high90.1Very high18 Ų1884.2 Ų84.27%0.07143%0.429CS..Hα-helixtrans-67.6-42.4-178-169.6-102.8000112.3L506 I530 V558 E559 E560 K564 N565 H566 R569 L571L506-Y562 HydrophobicContact CD1-CE2 4.26Å; I530-Y562 HydrophobicContact CB-CE2 4.46Å; I530-Y562 HydrophobicContact CD1-CD2 3.22Å; I530-Y562 HydrophobicContact CD1-CE2 3.52Å; I530-Y562 HydrophobicContact CD1-CG 4.01Å; I530-Y562 HydrophobicContact CG2-CD2 4.43Å; I530-Y562 HydrophobicContact CG2-CE2 3.72Å; V558-Y562 WeakPolarHBondContact O-CB 2.93Å; V558-Y562 PolarHBondContact O-N 3.3Å; E559-Y562 PolarHBondContact O-N 3.44Å; E560-Y562 VanDerWaalsContact C-N 3.3Å; E560-Y562 PolarHBondContact O-N 3.28Å; Y562-K564 VanDerWaalsContact C-N 3.3Å; Y562-K564 PolarHBondContact O-N 3.42Å; Y562-N565 PolarHBondContact O-N 2.92Å; Y562-H566 HydrophobicContact CD1-CB 4.4Å; Y562-H566 AromaticContact CD2-CD2 3.6Å; Y562-H566 HydrophobicContact CE1-CB 3.99Å; Y562-H566 AromaticContact CE2-CD2 3.23Å; Y562-H566 WeakPolarHBondContact CE2-CD2 3.38Å; Y562-H566 AromaticContact CE2-NE2 3.89Å; Y562-H566 AromaticContact CZ-CD2 3.57Å; Y562-H566 AromaticContact CZ-CG 3.98Å; Y562-H566 PolarHBondContact O-N 3.3Å; Y562-R569 HydrophobicContact CE1-CB 3.92Å; Y562-R569 WeakPolarHBondContact OH-CD 3.38Å; Y562-R569 PolarHBondContact OH-NH1 3.25Å; Y562-L571 HydrophobicContact CD1-CD1 3.82Å; Y562-L571 HydrophobicContact CD1-CD2 3.75Å; Y562-L571 HydrophobicContact CD1-CG 3.78Å; Y562-L571 HydrophobicContact CE1-CD2 3.74Å; Y562-L571 HydrophobicContact CE1-CG 4.21Å; Y562-L571 HydrophobicContact CG-CD1 3.88Å; Y562-L571 HydrophobicContact CG-CD2 4.24Å; Y562-L571 HydrophobicContact CG-CG 4.32Å
563K92.2Very high90Very high165 Ų16584 Ų8472%0.71742%0.424SS*.Hα-helixtrans-62.5-35.8179.8-176.5-179.2177.1-173.80112.2E559 E560 N565E559-K563 VanDerWaalsContact O-CB 3.24Å; E559-K563 WeakPolarHBondContact O-CB 3.44Å; E559-K563 PolarHBondContact O-N 2.79Å; E560-K563 PolarHBondContact O-N 2.87Å; K563-N565 VanDerWaalsContact C-N 3.32Å; K563-N565 PolarHBondContact O-N 3.45Å
564K89.9Confident89.8Confident160 Ų16083.8 Ų83.870%0.69642%0.42SS*.Hα-helixtrans-64.1-36.7176.6-173.9175.4178.1179.10112.4E560 F561 Y562E560-K564 PolarHBondContact O-N 3.46Å; F561-K564 PolarHBondContact O-N 3.44Å; Y562-K564 VanDerWaalsContact C-N 3.3Å; Y562-K564 PolarHBondContact O-N 3.42Å
565N86.8Confident89.6Confident76 Ų7684.7 Ų84.741%0.40642%0.424SS..Hα-helixtrans-90.1-23.9-178.4-64.9-27.9000113.2F561 Y562 K563F561-N565 WeakPolarHBondContact CE2-ND2 3.24Å; F561-N565 PolarHBondContact O-N 2.81Å; F561-N565 PolarHBondContact O-ND2 3.11Å; Y562-N565 PolarHBondContact O-N 2.92Å; K563-N565 VanDerWaalsContact C-N 3.32Å; K563-N565 PolarHBondContact O-N 3.45Å
566H89.3Confident89.1Confident51 Ų5185 Ų8524%0.23643%0.425CS..  trans-137.697.2-175.2-59-65.4000112.5Y562Y562-H566 HydrophobicContact CD1-CB 4.4Å; Y562-H566 AromaticContact CD2-CD2 3.6Å; Y562-H566 HydrophobicContact CE1-CB 3.99Å; Y562-H566 AromaticContact CE2-CD2 3.23Å; Y562-H566 WeakPolarHBondContact CE2-CD2 3.38Å; Y562-H566 AromaticContact CE2-NE2 3.89Å; Y562-H566 AromaticContact CZ-CD2 3.57Å; Y562-H566 AromaticContact CZ-CG 3.98Å; Y562-H566 PolarHBondContact O-N 3.3Å
567S87.4Confident88.6Confident111 Ų11184 Ų8478%0.77642%0.415SS*.THydrogen-bonded Turntrans-72.4142.9173.658.90000112.6
568G89.7Confident88.5Confident92 Ų9282.6 Ų82.695%0.94841%0.414SS*.THydrogen-bonded Turntrans82.88.6172.600000115.5
569R90.6Very high88.5Confident155 Ų15585.6 Ų85.659%0.58543%0.429SS*.  trans-108152.4176.6-59.6-173.3-173.8172.30.9111Y562Y562-R569 HydrophobicContact CE1-CB 3.92Å; Y562-R569 WeakPolarHBondContact OH-CD 3.38Å; Y562-R569 PolarHBondContact OH-NH1 3.25Å
570K87Confident88.4Confident168 Ų16882.5 Ų82.573%0.7342%0.42SS*.  trans-122134.2174.7-174.8174.7-177.8175.10109.4
571L89.9Confident88.6Confident41 Ų4180.7 Ų80.722%0.21541%0.413CS..  trans-90.4146.5174.4-65.6178.5000110.7I530 E559 Y562I530-L571 HydrophobicContact CG2-CD2 3.99Å; E559-L571 HydrophobicContact CG-CD1 4.16Å; Y562-L571 HydrophobicContact CD1-CD1 3.82Å; Y562-L571 HydrophobicContact CD1-CD2 3.75Å; Y562-L571 HydrophobicContact CD1-CG 3.78Å; Y562-L571 HydrophobicContact CE1-CD2 3.74Å; Y562-L571 HydrophobicContact CE1-CG 4.21Å; Y562-L571 HydrophobicContact CG-CD1 3.88Å; Y562-L571 HydrophobicContact CG-CD2 4.24Å; Y562-L571 HydrophobicContact CG-CG 4.32Å
572H88.1Confident88.7Confident131 Ų13181.3 Ų81.361%0.60642%0.417SS*.  trans-133.1118.6173.6-71.3-67.1000107.9H574H572-H574 PolarHBondContact O-CD2 3.39Å; H572-H574 VanDerWaalsContact O-CD2 3.3Å
573W87.7Confident88.9Confident89 Ų8984.2 Ų84.234%0.33744%0.437SS..  trans-79132.7-178.2-66.990000111.6I555 V558 E559I555-W573 HydrophobicContact CB-CZ2 4.07Å; I555-W573 HydrophobicContact CG1-CD2 4.25Å; I555-W573 HydrophobicContact CG1-CE3 4.49Å; I555-W573 HydrophobicContact CG1-CH2 4.11Å; I555-W573 HydrophobicContact CG1-CZ2 3.86Å; I555-W573 HydrophobicContact CG1-CZ3 4.43Å; I555-W573 HydrophobicContact CG2-CZ2 3.87Å; V558-W573 HydrophobicContact CB-CH2 4.01Å; V558-W573 HydrophobicContact CB-CZ2 4.09Å; V558-W573 HydrophobicContact CG1-CH2 3.84Å; V558-W573 HydrophobicContact CG1-CZ2 4.02Å; V558-W573 HydrophobicContact CG2-CH2 4.37Å; E559-W573 HydrophobicContact CG-CZ2 4.38Å; E559-W573 PolarHBondContact OE1-NE1 3.35Å
574H85.7Confident89Confident81 Ų8177.2 Ų77.238%0.37541%0.406SS..  trans-117.179.7179.3-74-91000110.5S539 H572 L576 M577 S578S539-H574 PolarHBondContact OG-CE1 3.48Å; S539-H574 PolarHBondContact OG-ND1 3.49Å; H572-H574 PolarHBondContact O-CD2 3.39Å; H572-H574 VanDerWaalsContact O-CD2 3.3Å; H574-L576 PolarHBondContact O-N 3.03Å; H574-M577 PolarHBondContact O-N 3.48Å; H574-M577 VanDerWaalsContact O-N 3.15Å; H574-S578 PolarHBondContact O-OG 3.37Å
575H86.1Confident89.2Confident38 Ų3876.5 Ų76.518%0.17640%0.403CS..G310 helixtrans-62.1-28.7-176.9-56.5-56000113.6V545 M577 S578 T597 F598V545-H575 HydrophobicContact CG1-CB 3.86Å; H575-M577 PolarHBondContact O-N 2.93Å; H575-S578 WeakPolarHBondContact O-CB 3.42Å; H575-S578 PolarHBondContact O-N 2.83Å; H575-T597 HydrophobicContact CB-CG2 4.02Å; H575-T597 WeakPolarHBondContact O-CB 3.35Å; H575-F598 HydrophobicContact CB-CE1 4.2Å
576L80.8Confident89.6Confident40 Ų4074 Ų7421%0.20939%0.389CS..G310 helixtrans-58.7-31.8175.9179.165.9000113.3H574 F598 M699H574-L576 PolarHBondContact O-N 3.03Å; L576-F598 HydrophobicContact CB-CZ 4.16Å; L576-F598 HydrophobicContact CD1-CD2 4.4Å; L576-F598 HydrophobicContact CD1-CE2 3.66Å; L576-F598 HydrophobicContact CD1-CZ 4.16Å; L576-M699 HydrophobicContact CD2-CE 4.34Å
577M82.1Confident89.8Confident47 Ų4777.3 Ų77.323%0.23241%0.405CS..G310 helixtrans-93.2-1.8-179.5-63.5177.265.600112.4T459 I463 W536 H574 H575T459-M577 HydrophobicContact CG2-CE 3.44Å; T459-M577 VanDerWaalsContact CG2-CE 3.44Å; I463-M577 HydrophobicContact CD1-CE 3.87Å; I463-M577 HydrophobicContact CG1-CE 3.65Å; I463-M577 WeakPolarHBondContact CG2-O 3.44Å; W536-M577 HydrophobicContact CE3-CE 4.36Å; H574-M577 PolarHBondContact O-N 3.48Å; H574-M577 VanDerWaalsContact O-N 3.15Å; H575-M577 PolarHBondContact O-N 2.93Å
578S87.7Confident90.2Very high44 Ų4474 Ų7431%0.30838%0.38SS..  trans-94.5152.2-175.1-60.30000111.2H574 H575 T597H574-S578 PolarHBondContact O-OG 3.37Å; H575-S578 WeakPolarHBondContact O-CB 3.42Å; H575-S578 PolarHBondContact O-N 2.83Å; S578-T597 WeakPolarHBondContact CB-OG1 3.37Å; S578-T597 PolarHBondContact O-N 2.93Å; S578-T597 PolarHBondContact O-OG1 2.97Å
579N90.2Very high90.4Very high63 Ų6370.3 Ų70.334%0.33734%0.343SS..EExtended strand (participates in β ladder)trans-142.4169.1178.170.149.2000110.6L464 V595 I689L464-N579 WeakPolarHBondContact CD2-ND2 3.16Å; N579-V595 CarbonylContact C-O 3.44Å; N579-V595 VanDerWaalsContact CA-O 3.29Å; N579-V595 WeakPolarHBondContact CA-O 3.22Å; N579-V595 WeakPolarHBondContact CB-O 3.43Å; N579-I689 HydrophobicContact CB-CD1 3.57Å; N579-I689 HydrophobicContact CB-CG1 4.39Å
580G91.7Very high90.6Very high17 Ų1766.4 Ų66.418%0.17533%0.331CS..EExtended strand (participates in β ladder)trans-157.1164.817500000111.8E594 V595G580-E594 WeakPolarHBondContact O-CA 3.41Å; G580-V595 PolarHBondContact N-O 3.21Å; G580-V595 PolarHBondContact O-N 3.11Å
581I93.7Very high91.1Very high99 Ų9958.4 Ų58.451%0.50830%0.296SS..EExtended strand (participates in β ladder)trans-107.2122172-59.1171.4000107.3D592 L593 E594I581-D592 HydrophobicContact CG2-CB 4.01Å; I581-L593 CarbonylContact C-O 3.55Å; I581-L593 WeakPolarHBondContact CA-O 3.48Å; I581-E594 HydrophobicContact CG1-CB 4.22Å; I581-E594 HydrophobicContact CG1-CG 4.14Å
582I94.5Very high91.3Very high22 Ų2259.4 Ų59.411%0.11330%0.302CS..EExtended strand (participates in β ladder)trans-114.6147.2177.765.9171.9000110.1D592 L593 V595 L600 L603 F604I582-D592 WeakPolarHBondContact O-CA 2.96Å; I582-L593 HydrophobicContact CD1-CB 4.47Å; I582-L593 HydrophobicContact CG1-CB 3.87Å; I582-L593 PolarHBondContact N-O 3.18Å; I582-L593 PolarHBondContact O-N 3.17Å; I582-V595 HydrophobicContact CD1-CG1 4.45Å; I582-V595 HydrophobicContact CD1-CG2 4.06Å; I582-V595 HydrophobicContact CG1-CG2 4.04Å; I582-V595 HydrophobicContact CG2-CG2 4.13Å; I582-L600 HydrophobicContact CG2-CD1 3.66Å; I582-L600 HydrophobicContact CG2-CG 3.96Å; I582-L603 HydrophobicContact CD1-CB 4.27Å; I582-L603 HydrophobicContact CD1-CD1 3.58Å; I582-F604 HydrophobicContact CG2-CE2 4.01Å
583T95Very high91.7Very high79 Ų7953.2 Ų53.249%0.48527%0.273SS..EExtended strand (participates in β ladder)trans-89.7109.3172.4-62.20000109.7K585 Q590T583-K585 HydrophobicContact CG2-CG 4.22Å; T583-Q590 HydrophobicContact CG2-CG 3.5Å; T583-Q590 VanDerWaalsContact CG2-CG 3.5Å; T583-Q590 VanDerWaalsContact CG2-NE2 3.27Å
584F95.3Very high91.9Very high18 Ų1850.4 Ų50.48%0.07926%0.264CS..EExtended strand (participates in β ladder)trans-93.9119.7176.3179.5-93.2000110.5N586 Q590 Y591 L593 V647 V668 F672F584-N586 HydrophobicContact CE1-CB 4.01Å; F584-N586 HydrophobicContact CZ-CB 4.45Å; F584-Q590 CarbonylContact O-C 3.58Å; F584-Q590 WeakPolarHBondContact O-CA 3.16Å; F584-Y591 HydrophobicContact CD1-CD2 4.06Å; F584-Y591 PolarHBondContact N-O 2.79Å; F584-Y591 PolarHBondContact O-N 3.01Å; F584-L593 HydrophobicContact CB-CD1 3.41Å; F584-L593 VanDerWaalsContact CB-CD1 3.41Å; F584-L593 HydrophobicContact CB-CD2 4.45Å; F584-L593 HydrophobicContact CB-CG 3.63Å; F584-L593 HydrophobicContact CD1-CD1 4.4Å; F584-L593 HydrophobicContact CD2-CD1 3.92Å; F584-L593 HydrophobicContact CG-CD1 3.67Å; F584-L593 HydrophobicContact CG-CG 4.34Å; F584-V647 HydrophobicContact CD2-CG1 4.33Å; F584-V647 HydrophobicContact CE2-CG1 3.85Å; F584-V647 HydrophobicContact CZ-CG1 4.09Å; F584-V668 HydrophobicContact CE2-CG1 3.67Å; F584-V668 HydrophobicContact CZ-CG1 3.53Å; F584-F672 HydrophobicContact CD1-CD1 4.04Å; F584-F672 HydrophobicContact CD1-CE1 4.39Å; F584-F672 HydrophobicContact CE1-CB 4.23Å; F584-F672 AromaticContact CE1-CD1 3.65Å; F584-F672 HydrophobicContact CE1-CD1 3.65Å; F584-F672 HydrophobicContact CE1-CE1 4.38Å; F584-F672 HydrophobicContact CE1-CG 4.21Å
585K95Very high92.3Very high144 Ų14446.6 Ų46.663%0.62625%0.246SC*.EExtended strand (participates in β ladder)trans-115.2134.4177.7-68.5178.9-179.31770110.1T583 Q590T583-K585 HydrophobicContact CG2-CG 4.22Å; K585-Q590 HydrophobicContact CG-CB 4.12Å; K585-Q590 HydrophobicContact CG-CG 3.86Å
586N93.8Very high92.5Very high23 Ų2345.6 Ų45.612%0.12324%0.243CC..  trans-138.4-169.6172.471.9-4.7000110.5F584 V588 G589 N669 Q670 F672F584-N586 HydrophobicContact CE1-CB 4.01Å; F584-N586 HydrophobicContact CZ-CB 4.45Å; N586-V588 PolarHBondContact O-N 3.35Å; N586-V588 PolarHBondContact OD1-N 3.43Å; N586-G589 PolarHBondContact N-O 3.11Å; N586-G589 VanDerWaalsContact N-O 3.09Å; N586-G589 PolarHBondContact OD1-N 2.98Å; N586-G589 PolarHBondContact OD1-O 3.28Å; N586-N669 PolarHBondContact ND2-O 3.26Å; N586-Q670 PolarHBondContact ND2-O 2.91Å; N586-F672 WeakPolarHBondContact ND2-CB 3.42Å; N586-F672 PolarHBondContact ND2-N 3.31Å; N586-F672 PolarHBondContact ND2-O 3.06Å
587E94.9Very high93Very high121 Ų12144 Ų4457%0.56524%0.235SC*.SBendtrans-67.6-21.9-179-63.6-177.2173.400113.8R611 Q670E587-R611 IonicContact OE1-CZ 2.73Å; E587-R611 IonicContact OE1-NE 2.66Å; E587-R611 IonicContact OE1-NH2 2.7Å; E587-R611 PolarHBondContact OE1-NH2 3.46Å; E587-Q670 HydrophobicContact CG-CB 4.1Å; E587-Q670 PolarHBondContact N-O 3.14Å
588V94Very high93.4Very high41 Ų4142.2 Ų42.225%0.24823%0.226CC..SBendtrans-89.8-40.2-178.3-176.40000112.5N586 V680N586-V588 PolarHBondContact O-N 3.35Å; N586-V588 PolarHBondContact OD1-N 3.43Å; V588-V680 HydrophobicContact CG1-CG1 3.91Å
589G93.6Very high93.7Very high16 Ų1640.3 Ų40.317%0.16521%0.212CC..  trans-176.3-169-170.300000115.6N586 K682N586-G589 PolarHBondContact N-O 3.11Å; N586-G589 VanDerWaalsContact N-O 3.09Å; N586-G589 PolarHBondContact OD1-N 2.98Å; N586-G589 PolarHBondContact OD1-O 3.28Å; G589-K682 CarbonylContact C-O 3.47Å; G589-K682 VanDerWaalsContact CA-O 3.23Å; G589-K682 WeakPolarHBondContact CA-O 3.16Å
590Q96.1Very high93.8Very high72 Ų7237.9 Ų37.934%0.33620%0.199SC..EExtended strand (participates in β ladder)trans-127.4124.4-179177.2-179.5-30.300109.8T583 F584 K585 K682 R683T583-Q590 HydrophobicContact CG2-CG 3.5Å; T583-Q590 VanDerWaalsContact CG2-CG 3.5Å; T583-Q590 VanDerWaalsContact CG2-NE2 3.27Å; F584-Q590 CarbonylContact O-C 3.58Å; F584-Q590 WeakPolarHBondContact O-CA 3.16Å; K585-Q590 HydrophobicContact CG-CB 4.12Å; K585-Q590 HydrophobicContact CG-CG 3.86Å; Q590-K682 PolarHBondContact N-O 3.19Å; Q590-R683 VanDerWaalsContact O-CA 3.25Å; Q590-R683 WeakPolarHBondContact O-CA 3.34Å
591Y96.2Very high93.9Very high0 Ų037.4 Ų37.40%019%0.193CC..EExtended strand (participates in β ladder)trans-128.2144.2-173.9-49.8-89000110.8F584 F672 S673 L674 Q681 G684F584-Y591 HydrophobicContact CD1-CD2 4.06Å; F584-Y591 PolarHBondContact N-O 2.79Å; F584-Y591 PolarHBondContact O-N 3.01Å; Y591-F672 HydrophobicContact CD1-CE1 4.3Å; Y591-F672 AromaticContact CD2-CD1 3.85Å; Y591-F672 HydrophobicContact CD2-CD1 3.85Å; Y591-F672 AromaticContact CD2-CE1 3.78Å; Y591-F672 HydrophobicContact CD2-CE1 3.78Å; Y591-F672 AromaticContact CE2-CD1 3.8Å; Y591-F672 HydrophobicContact CE2-CD1 3.8Å; Y591-F672 HydrophobicContact CE2-CE1 4.06Å; Y591-F672 HydrophobicContact CG-CD1 4.43Å; Y591-F672 AromaticContact CG-CE1 3.9Å; Y591-F672 HydrophobicContact CG-CE1 3.9Å; Y591-F672 PolarHBondContact OH-O 3.28Å; Y591-S673 VanDerWaalsContact OH-CA 3.25Å; Y591-S673 WeakPolarHBondContact OH-CA 3.5Å; Y591-S673 VanDerWaalsContact OH-CB 3.24Å; Y591-S673 WeakPolarHBondContact OH-CB 3.49Å; Y591-L674 HydrophobicContact CD1-CD1 3.97Å; Y591-L674 HydrophobicContact CD1-CG 4.07Å; Y591-L674 HydrophobicContact CE1-CB 4.25Å; Y591-L674 HydrophobicContact CE1-CD1 4.34Å; Y591-L674 HydrophobicContact CE1-CG 4.13Å; Y591-Q681 VanDerWaalsContact CE1-O 3.27Å; Y591-Q681 WeakPolarHBondContact CE1-O 3.47Å; Y591-Q681 PolarHBondContact OH-O 3.1Å; Y591-G684 CarbonylContact C-O 3.59Å; Y591-G684 WeakPolarHBondContact CA-O 3.34Å
592D96.1Very high94Very high63 Ų6332.7 Ų32.734%0.33717%0.169SC..EExtended strand (participates in β ladder)trans-94.1110.8172.8-64.1-25.7000108.3I581 I582 G684 K685 I686I581-D592 HydrophobicContact CG2-CB 4.01Å; I582-D592 WeakPolarHBondContact O-CA 2.96Å; D592-G684 PolarHBondContact N-O 2.8Å; D592-K685 HydrophobicContact CB-CB 4.35Å; D592-K685 HydrophobicContact CB-CG 4.23Å; D592-K685 CarbonylContact O-C 3.55Å; D592-K685 VanDerWaalsContact O-CA 3.28Å; D592-K685 WeakPolarHBondContact O-CA 3.46Å; D592-I686 PolarHBondContact O-N 3.3Å
593L95.1Very high94Very high0 Ų032.2 Ų32.20%017%0.167CC..EExtended strand (participates in β ladder)trans-99.1116.7179.8-51.5-174.7000108.8I581 I582 F584 V595 V647 I686 L688I581-L593 CarbonylContact C-O 3.55Å; I581-L593 WeakPolarHBondContact CA-O 3.48Å; I582-L593 HydrophobicContact CD1-CB 4.47Å; I582-L593 HydrophobicContact CG1-CB 3.87Å; I582-L593 PolarHBondContact N-O 3.18Å; I582-L593 PolarHBondContact O-N 3.17Å; F584-L593 HydrophobicContact CB-CD1 3.41Å; F584-L593 VanDerWaalsContact CB-CD1 3.41Å; F584-L593 HydrophobicContact CB-CD2 4.45Å; F584-L593 HydrophobicContact CB-CG 3.63Å; F584-L593 HydrophobicContact CD1-CD1 4.4Å; F584-L593 HydrophobicContact CD2-CD1 3.92Å; F584-L593 HydrophobicContact CG-CD1 3.67Å; F584-L593 HydrophobicContact CG-CG 4.34Å; L593-V595 HydrophobicContact CB-CG1 3.93Å; L593-V647 HydrophobicContact CD1-CG1 4.19Å; L593-V647 HydrophobicContact CD1-CG2 4.49Å; L593-I686 HydrophobicContact CD2-CB 3.93Å; L593-I686 HydrophobicContact CD2-CD1 3.73Å; L593-I686 HydrophobicContact CD2-CG1 4.07Å; L593-L688 HydrophobicContact CB-CD1 4.07Å; L593-L688 HydrophobicContact CD1-CD1 3.88Å; L593-L688 HydrophobicContact CD2-CD1 4.11Å; L593-L688 HydrophobicContact CG-CD1 4.24Å
594E93.1Very high94Very high31 Ų3131.4 Ų31.415%0.14516%0.157CC..EExtended strand (participates in β ladder)trans-86.4113.5168.6-172.5-170.6166.300107.9G580 I581 I686 N687 L688 I689G580-E594 WeakPolarHBondContact O-CA 3.41Å; I581-E594 HydrophobicContact CG1-CB 4.22Å; I581-E594 HydrophobicContact CG1-CG 4.14Å; E594-I686 PolarHBondContact N-O 3.25Å; E594-N687 PolarHBondContact OE1-ND2 3.37Å; E594-N687 PolarHBondContact OE2-ND2 3.4Å; E594-L688 WeakPolarHBondContact O-CA 3.43Å; E594-L688 PolarHBondContact O-N 2.97Å; E594-I689 HydrophobicContact CG-CD1 3.67Å; E594-I689 HydrophobicContact CG-CG1 4.19Å; E594-I689 PolarHBondContact O-N 2.79Å; E594-I689 VanDerWaalsContact O-N 3.17Å; E594-I689 WeakPolarHBondContact OE1-CD1 3.47Å
595V92.5Very high93.9Very high0 Ų031.4 Ų31.40%016%0.16CC..EExtended strand (participates in β ladder)trans-131.1155.2-166.9-69.90000110.9N579 G580 I582 L593 Q599 L600 L603 L688N579-V595 CarbonylContact C-O 3.44Å; N579-V595 VanDerWaalsContact CA-O 3.29Å; N579-V595 WeakPolarHBondContact CA-O 3.22Å; N579-V595 WeakPolarHBondContact CB-O 3.43Å; G580-V595 PolarHBondContact N-O 3.21Å; G580-V595 PolarHBondContact O-N 3.11Å; I582-V595 HydrophobicContact CD1-CG1 4.45Å; I582-V595 HydrophobicContact CD1-CG2 4.06Å; I582-V595 HydrophobicContact CG1-CG2 4.04Å; I582-V595 HydrophobicContact CG2-CG2 4.13Å; L593-V595 HydrophobicContact CB-CG1 3.93Å; V595-Q599 HydrophobicContact CB-CB 3.89Å; V595-Q599 HydrophobicContact CG1-CB 4.27Å; V595-L600 HydrophobicContact CG2-CB 3.94Å; V595-L600 HydrophobicContact CG2-CD1 4.37Å; V595-L600 HydrophobicContact CG2-CG 4.48Å; V595-L603 HydrophobicContact CG1-CD1 4.21Å; V595-L688 HydrophobicContact CG1-CB 4.05Å; V595-L688 HydrophobicContact CG1-CD1 3.99Å
596T90.7Very high93.9Very high18 Ų1824.9 Ų24.911%0.1113%0.131CC..EExtended strand (participates in β ladder)trans-70.2159.9167.261.50000110.7F598 Q599 L600 I689 L692T596-F598 PolarHBondContact O-N 3.21Å; T596-Q599 PolarHBondContact O-N 3.28Å; T596-Q599 WeakPolarHBondContact OG1-CB 3.04Å; T596-Q599 VanDerWaalsContact OG1-CG 3.29Å; T596-Q599 WeakPolarHBondContact OG1-CG 3.28Å; T596-Q599 PolarHBondContact OG1-N 3.13Å; T596-Q599 PolarHBondContact OG1-OE1 3.46Å; T596-L600 WeakPolarHBondContact O-CB 3.48Å; T596-L600 PolarHBondContact O-N 3.38Å; T596-I689 HydrophobicContact CG2-CG1 4.39Å; T596-I689 HydrophobicContact CG2-CG2 4.26Å; T596-L692 HydrophobicContact CG2-CD1 4.21Å; T596-L692 HydrophobicContact CG2-CD2 4.05Å; T596-L692 HydrophobicContact CG2-CG 3.75Å
597T91Very high93.9Very high7 Ų728.7 Ų28.74%0.04315%0.152CC..Hα-helixtrans-58.7-32.9176.4-59.50000113.1L547 H575 S578 L600 A601L547-T597 HydrophobicContact CD2-CG2 3.46Å; L547-T597 VanDerWaalsContact CD2-CG2 3.46Å; H575-T597 HydrophobicContact CB-CG2 4.02Å; H575-T597 WeakPolarHBondContact O-CB 3.35Å; S578-T597 WeakPolarHBondContact CB-OG1 3.37Å; S578-T597 PolarHBondContact O-N 2.93Å; S578-T597 PolarHBondContact O-OG1 2.97Å; T597-L600 WeakPolarHBondContact O-CB 3.49Å; T597-L600 PolarHBondContact O-N 3.01Å; T597-A601 PolarHBondContact O-N 3.03Å
598F91.2Very high93.6Very high8 Ų832.3 Ų32.34%0.03517%0.169CC..Hα-helixtrans-70.1-42.7176.3-62.6-12000112.4V543 V545 H575 L576 T596 L600 A601 V602 L625 E629 T633V543-F598 HydrophobicContact CB-CZ 3.96Å; V543-F598 HydrophobicContact CG1-CE1 4.21Å; V543-F598 HydrophobicContact CG1-CE2 4.13Å; V543-F598 HydrophobicContact CG1-CZ 3.53Å; V545-F598 HydrophobicContact CB-CD1 4.34Å; V545-F598 HydrophobicContact CB-CE1 4.18Å; V545-F598 HydrophobicContact CG1-CD1 4.44Å; V545-F598 HydrophobicContact CG1-CE1 4.08Å; V545-F598 HydrophobicContact CG2-CD1 4.16Å; H575-F598 HydrophobicContact CB-CE1 4.2Å; L576-F598 HydrophobicContact CB-CZ 4.16Å; L576-F598 HydrophobicContact CD1-CD2 4.4Å; L576-F598 HydrophobicContact CD1-CE2 3.66Å; L576-F598 HydrophobicContact CD1-CZ 4.16Å; T596-F598 PolarHBondContact O-N 3.21Å; F598-L600 VanDerWaalsContact C-N 3.26Å; F598-L600 PolarHBondContact O-N 3.28Å; F598-A601 PolarHBondContact O-N 3.22Å; F598-V602 WeakPolarHBondContact O-CG2 3.37Å; F598-V602 PolarHBondContact O-N 3.38Å; F598-L625 HydrophobicContact CB-CD1 4.06Å; F598-L625 HydrophobicContact CB-CD2 4.34Å; F598-L625 HydrophobicContact CD1-CD2 3.62Å; F598-L625 HydrophobicContact CD2-CD2 4.1Å; F598-L625 HydrophobicContact CE1-CD2 3.83Å; F598-L625 HydrophobicContact CE2-CD2 4.28Å; F598-L625 HydrophobicContact CG-CD1 4.38Å; F598-L625 HydrophobicContact CG-CD2 3.77Å; F598-L625 HydrophobicContact CZ-CD2 4.17Å; F598-E629 HydrophobicContact CE2-CG 4.46Å; F598-T633 HydrophobicContact CB-CG2 4Å
599Q93.1Very high93.5Very high5 Ų534 Ų342%0.02317%0.171CC..Hα-helixtrans-61.5-38.8172.6-73.9167.9-3000111.1V595 T596 V602 L603 T633 S636 L637 L688V595-Q599 HydrophobicContact CB-CB 3.89Å; V595-Q599 HydrophobicContact CG1-CB 4.27Å; T596-Q599 PolarHBondContact O-N 3.28Å; T596-Q599 WeakPolarHBondContact OG1-CB 3.04Å; T596-Q599 VanDerWaalsContact OG1-CG 3.29Å; T596-Q599 WeakPolarHBondContact OG1-CG 3.28Å; T596-Q599 PolarHBondContact OG1-N 3.13Å; T596-Q599 PolarHBondContact OG1-OE1 3.46Å; Q599-V602 PolarHBondContact O-N 3.45Å; Q599-L603 WeakPolarHBondContact O-CB 3.48Å; Q599-L603 VanDerWaalsContact O-CG 3.25Å; Q599-L603 WeakPolarHBondContact O-CG 3.32Å; Q599-L603 PolarHBondContact O-N 3.32Å; Q599-T633 HydrophobicContact CB-CG2 4.4Å; Q599-T633 HydrophobicContact CG-CG2 3.92Å; Q599-S636 PolarHBondContact NE2-OG 2.87Å; Q599-L637 HydrophobicContact CB-CD2 4.28Å; Q599-L637 HydrophobicContact CG-CD1 4.42Å; Q599-L637 HydrophobicContact CG-CD2 4.05Å; Q599-L637 HydrophobicContact CG-CG 4.22Å; Q599-L688 PolarHBondContact NE2-O 2.92Å
600L93.9Very high93.4Very high12 Ų1236.8 Ų36.86%0.06319%0.186CC..Hα-helixtrans-61.7-50.3176.4-171.6155.3000111P548 L551 I582 V595 T596 T597 F598 V602 L603 F604P548-L600 HydrophobicContact CG-CD2 3.4Å; P548-L600 VanDerWaalsContact CG-CD2 3.4Å; L551-L600 HydrophobicContact CD1-CD1 4.49Å; L551-L600 HydrophobicContact CD1-CD2 4.05Å; I582-L600 HydrophobicContact CG2-CD1 3.66Å; I582-L600 HydrophobicContact CG2-CG 3.96Å; V595-L600 HydrophobicContact CG2-CB 3.94Å; V595-L600 HydrophobicContact CG2-CD1 4.37Å; V595-L600 HydrophobicContact CG2-CG 4.48Å; T596-L600 WeakPolarHBondContact O-CB 3.48Å; T596-L600 PolarHBondContact O-N 3.38Å; T597-L600 WeakPolarHBondContact O-CB 3.49Å; T597-L600 PolarHBondContact O-N 3.01Å; F598-L600 VanDerWaalsContact C-N 3.26Å; F598-L600 PolarHBondContact O-N 3.28Å; L600-V602 VanDerWaalsContact C-N 3.32Å; L600-V602 PolarHBondContact O-N 3.35Å; L600-L603 PolarHBondContact O-N 3.03Å; L600-F604 HydrophobicContact CD2-CD2 3.93Å; L600-F604 HydrophobicContact CD2-CE2 3.89Å; L600-F604 HydrophobicContact CD2-CG 4.47Å; L600-F604 HydrophobicContact CD2-CZ 4.4Å; L600-F604 HydrophobicContact CG-CD2 4.13Å; L600-F604 HydrophobicContact CG-CE2 3.93Å; L600-F604 VanDerWaalsContact O-CD2 3.22Å; L600-F604 WeakPolarHBondContact O-CD2 3.04Å; L600-F604 PolarHBondContact O-N 3.26Å
601A93.5Very high93.2Very high7 Ų742.6 Ų42.66%0.05820%0.204CC..Hα-helixtrans-56.9-44176.300000112.2V545 T597 F598 T623V545-A601 HydrophobicContact CG2-CB 3.76Å; T597-A601 PolarHBondContact O-N 3.03Å; F598-A601 PolarHBondContact O-N 3.22Å; A601-T623 HydrophobicContact CB-CG2 4.34Å
602V94.6Very high93.1Very high0 Ų047.5 Ų47.50%023%0.228CC..Hα-helixtrans-62.5-49.4176.3168.70000111.7F598 Q599 L600 F604 A605 W606 T623 L625 L630 T633 L634 L637 L648F598-V602 WeakPolarHBondContact O-CG2 3.37Å; F598-V602 PolarHBondContact O-N 3.38Å; Q599-V602 PolarHBondContact O-N 3.45Å; L600-V602 VanDerWaalsContact C-N 3.32Å; L600-V602 PolarHBondContact O-N 3.35Å; V602-F604 VanDerWaalsContact C-N 3.3Å; V602-F604 PolarHBondContact O-N 3.3Å; V602-A605 VanDerWaalsContact O-CB 3.24Å; V602-A605 WeakPolarHBondContact O-CB 3.33Å; V602-A605 PolarHBondContact O-N 3.2Å; V602-W606 HydrophobicContact CG1-CZ3 3.95Å; V602-W606 WeakPolarHBondContact O-CZ3 3.47Å; V602-T623 HydrophobicContact CG2-CG2 4.01Å; V602-L625 HydrophobicContact CG2-CD1 4.13Å; V602-L630 HydrophobicContact CG2-CD1 3.78Å; V602-T633 HydrophobicContact CB-CG2 4.4Å; V602-T633 HydrophobicContact CG2-CG2 3.78Å; V602-L634 HydrophobicContact CG1-CD2 3.67Å; V602-L637 HydrophobicContact CB-CD1 4.33Å; V602-L637 HydrophobicContact CG1-CD1 3.83Å; V602-L648 HydrophobicContact CG1-CD1 4.42Å
603L95.4Very high93.1Very high12 Ų1249.7 Ų49.76%0.06323%0.234CC..Hα-helixtrans-66.2-33.1-176.1-71.5170.4000112.5I582 V595 Q599 L600 A605 W606 L637 V647 L648I582-L603 HydrophobicContact CD1-CB 4.27Å; I582-L603 HydrophobicContact CD1-CD1 3.58Å; V595-L603 HydrophobicContact CG1-CD1 4.21Å; Q599-L603 WeakPolarHBondContact O-CB 3.48Å; Q599-L603 VanDerWaalsContact O-CG 3.25Å; Q599-L603 WeakPolarHBondContact O-CG 3.32Å; Q599-L603 PolarHBondContact O-N 3.32Å; L600-L603 PolarHBondContact O-N 3.03Å; L603-A605 PolarHBondContact O-N 3.48Å; L603-W606 PolarHBondContact O-N 3.47Å; L603-L637 HydrophobicContact CD1-CD2 4.15Å; L603-L637 HydrophobicContact CD2-CD1 4.16Å; L603-L637 HydrophobicContact CD2-CD2 4.5Å; L603-L637 HydrophobicContact CG-CD1 4.11Å; L603-L637 HydrophobicContact CG-CD2 4.47Å; L603-V647 HydrophobicContact CD2-CG1 4Å; L603-L648 HydrophobicContact CD2-CD1 4.43Å; L603-L648 HydrophobicContact CD2-CD2 4.07Å; L603-L648 HydrophobicContact CD2-CG 4.28Å
604F94.3Very high93.2Very high62 Ų6249.9 Ų49.927%0.27224%0.235SC..Hα-helixtrans-65.6-19177.9-90.9-119.8000113.3P548 I582 L600 V602 W606 N607P548-F604 HydrophobicContact CB-CD1 3.44Å; P548-F604 VanDerWaalsContact CB-CD1 3.44Å; P548-F604 HydrophobicContact CB-CE1 3.6Å; P548-F604 HydrophobicContact CB-CG 4.23Å; P548-F604 HydrophobicContact CB-CZ 4.49Å; P548-F604 HydrophobicContact CG-CB 4.05Å; P548-F604 HydrophobicContact CG-CD1 3.31Å; P548-F604 HydrophobicContact CG-CD2 4.19Å; P548-F604 HydrophobicContact CG-CE1 3.7Å; P548-F604 HydrophobicContact CG-CG 3.59Å; P548-F604 HydrophobicContact CG-CZ 4.28Å; I582-F604 HydrophobicContact CG2-CE2 4.01Å; L600-F604 HydrophobicContact CD2-CD2 3.93Å; L600-F604 HydrophobicContact CD2-CE2 3.89Å; L600-F604 HydrophobicContact CD2-CG 4.47Å; L600-F604 HydrophobicContact CD2-CZ 4.4Å; L600-F604 HydrophobicContact CG-CD2 4.13Å; L600-F604 HydrophobicContact CG-CE2 3.93Å; L600-F604 VanDerWaalsContact O-CD2 3.22Å; L600-F604 WeakPolarHBondContact O-CD2 3.04Å; L600-F604 PolarHBondContact O-N 3.26Å; V602-F604 VanDerWaalsContact C-N 3.3Å; V602-F604 PolarHBondContact O-N 3.3Å; F604-W606 PolarHBondContact O-N 3.5Å; F604-N607 WeakPolarHBondContact CD1-ND2 3.49Å; F604-N607 PolarHBondContact O-N 3.48Å; F604-N607 VanDerWaalsContact O-N 3.08Å
605A94.4Very high93.4Very high18 Ų1849.1 Ų49.115%0.14923%0.233CC..THydrogen-bonded Turntrans-59.7-18.5174.900000113.8V602 L603 R609 I614 L619V602-A605 VanDerWaalsContact O-CB 3.24Å; V602-A605 WeakPolarHBondContact O-CB 3.33Å; V602-A605 PolarHBondContact O-N 3.2Å; L603-A605 PolarHBondContact O-N 3.48Å; A605-R609 WeakPolarHBondContact O-CG 3.25Å; A605-R609 PolarHBondContact O-NE 2.86Å; A605-I614 HydrophobicContact CB-CD1 4.21Å; A605-L619 HydrophobicContact CB-CD2 3.78Å
606W95.2Very high93.6Very high6 Ų649.1 Ų49.12%0.02323%0.233CC..THydrogen-bonded Turntrans-98.3-4.2177.6-75.6-86.4000115V602 L603 F604 Q608 R609 P610 E612 I614 L619 L648 F666 V668V602-W606 HydrophobicContact CG1-CZ3 3.95Å; V602-W606 WeakPolarHBondContact O-CZ3 3.47Å; L603-W606 PolarHBondContact O-N 3.47Å; F604-W606 PolarHBondContact O-N 3.5Å; W606-Q608 VanDerWaalsContact C-N 3.3Å; W606-Q608 PolarHBondContact O-N 3.02Å; W606-R609 CarbonylContact O-C 3.58Å; W606-R609 PolarHBondContact O-N 3.39Å; W606-P610 WeakPolarHBondContact O-CA 3.46Å; W606-P610 VanDerWaalsContact O-N 3.14Å; W606-E612 PolarHBondContact NE1-O 3.07Å; W606-I614 HydrophobicContact CD2-CD1 3.87Å; W606-I614 HydrophobicContact CG-CD1 4.1Å; W606-I614 HydrophobicContact CZ2-CB 4.12Å; W606-I614 HydrophobicContact CZ2-CD1 3.94Å; W606-I614 HydrophobicContact CZ2-CG1 4.11Å; W606-L619 HydrophobicContact CH2-CD1 3.78Å; W606-L619 HydrophobicContact CH2-CD2 3.7Å; W606-L619 HydrophobicContact CH2-CG 4.37Å; W606-L619 HydrophobicContact CZ2-CD1 4.37Å; W606-L619 HydrophobicContact CZ2-CD2 4.32Å; W606-L619 HydrophobicContact CZ3-CD2 3.91Å; W606-L648 HydrophobicContact CE3-CD2 4.46Å; W606-L648 HydrophobicContact CH2-CD1 3.97Å; W606-L648 HydrophobicContact CH2-CD2 4.21Å; W606-L648 HydrophobicContact CZ3-CD1 4.06Å; W606-L648 HydrophobicContact CZ3-CD2 4.17Å; W606-F666 HydrophobicContact CH2-CB 3.98Å; W606-F666 HydrophobicContact CZ2-CB 3.85Å; W606-F666 WeakPolarHBondContact CZ2-O 3.44Å; W606-V668 HydrophobicContact CB-CG2 3.7Å; W606-V668 HydrophobicContact CD2-CG2 3.81Å; W606-V668 HydrophobicContact CE3-CG2 4.43Å; W606-V668 HydrophobicContact CG-CG2 3.46Å; W606-V668 VanDerWaalsContact CG-CG2 3.46Å
607N92.2Very high93.9Very high104 Ų10453.2 Ų53.256%0.55625%0.251SS*.THydrogen-bonded Turntrans-59.3-39.2-176-81.3-9.7000113F604F604-N607 WeakPolarHBondContact CD1-ND2 3.49Å; F604-N607 PolarHBondContact O-N 3.48Å; F604-N607 VanDerWaalsContact O-N 3.08Å
608Q88.7Confident94.2Very high196 Ų19656.5 Ų56.592%0.91627%0.268SS*.THydrogen-bonded Turntrans-88.1-12.3177.8-64.2179.4-1.700113.3W606W606-Q608 VanDerWaalsContact C-N 3.3Å; W606-Q608 PolarHBondContact O-N 3.02Å
609R92.5Very high94.4Very high78 Ų7856.1 Ų56.129%0.29427%0.267SS..  trans-140.964.2-174.252179.3163.4-171.5-4.6112.3A605 W606 R611 E612 I614A605-R609 WeakPolarHBondContact O-CG 3.25Å; A605-R609 PolarHBondContact O-NE 2.86Å; W606-R609 CarbonylContact O-C 3.58Å; W606-R609 PolarHBondContact O-N 3.39Å; R609-R611 PolarHBondContact O-N 3.28Å; R609-E612 HydrophobicContact CB-CB 4.06Å; R609-E612 HydrophobicContact CB-CG 3.88Å; R609-E612 WeakPolarHBondContact CD-OE2 3.24Å; R609-E612 HydrophobicContact CG-CB 4.43Å; R609-E612 PolarHBondContact O-N 2.92Å; R609-I614 HydrophobicContact CG-CD1 4.4Å; R609-I614 VanDerWaalsContact NE-CD1 3.35Å
610P90.9Very high94.5Very high73 Ų7359.2 Ų59.247%0.47428%0.28SS..THydrogen-bonded Turntrans-64.9-19.5-165.6-23.935.5000115.6W606 Q670W606-P610 WeakPolarHBondContact O-CA 3.46Å; W606-P610 VanDerWaalsContact O-N 3.14Å; P610-Q670 PolarHBondContact O-NE2 2.94Å
611R92.4Very high94.5Very high194 Ų19464.4 Ų64.473%0.73231%0.307SS*.THydrogen-bonded Turntrans-112.22.4-176-67-172.9170.6-176.4-2.5114E587 R609E587-R611 IonicContact OE1-CZ 2.73Å; E587-R611 IonicContact OE1-NE 2.66Å; E587-R611 IonicContact OE1-NH2 2.7Å; E587-R611 PolarHBondContact OE1-NH2 3.46Å; R609-R611 PolarHBondContact O-N 3.28Å
612E94.5Very high94.5Very high104 Ų10466.2 Ų66.249%0.48632%0.323SS..  trans-81.3150.6-179.1-72.3-175.5-165.500112.8W606 R609W606-E612 PolarHBondContact NE1-O 3.07Å; R609-E612 HydrophobicContact CB-CB 4.06Å; R609-E612 HydrophobicContact CB-CG 3.88Å; R609-E612 WeakPolarHBondContact CD-OE2 3.24Å; R609-E612 HydrophobicContact CG-CB 4.43Å; R609-E612 PolarHBondContact O-N 2.92Å
613K96.4Very high94.4Very high109 Ų10966.3 Ų66.347%0.47432%0.323SS..  trans-92.2121.5167.1-67.1-175.3176.3-176.70108.4E651 L665 F666K613-E651 VanDerWaalsContact CD-OE1 3.28Å; K613-E651 WeakPolarHBondContact CD-OE1 3.23Å; K613-E651 WeakPolarHBondContact CE-OE1 3.32Å; K613-E651 IonicContact NZ-OE1 3.64Å; K613-E651 PolarHBondContact NZ-OE1 2.91Å; K613-E651 IonicContact NZ-OE2 2.66Å; K613-E651 PolarHBondContact NZ-OE2 3.49Å; K613-L665 HydrophobicContact CB-CB 4.28Å; K613-L665 HydrophobicContact CB-CD1 4.46Å; K613-L665 HydrophobicContact CD-CD1 4.34Å; K613-F666 CarbonylContact C-O 3.57Å; K613-F666 VanDerWaalsContact CA-O 3.3Å; K613-F666 WeakPolarHBondContact CA-O 3.44Å
614I96.7Very high94.4Very high3 Ų371.4 Ų71.42%0.01535%0.347CS..EExtended strand (participates in β ladder)trans-109.9129.8-178.2-49.6176.8000108.6A605 W606 R609 N618 L619 F666A605-I614 HydrophobicContact CB-CD1 4.21Å; W606-I614 HydrophobicContact CD2-CD1 3.87Å; W606-I614 HydrophobicContact CG-CD1 4.1Å; W606-I614 HydrophobicContact CZ2-CB 4.12Å; W606-I614 HydrophobicContact CZ2-CD1 3.94Å; W606-I614 HydrophobicContact CZ2-CG1 4.11Å; R609-I614 HydrophobicContact CG-CD1 4.4Å; R609-I614 VanDerWaalsContact NE-CD1 3.35Å; I614-N618 HydrophobicContact CG2-CB 3.63Å; I614-L619 HydrophobicContact CB-CD2 4.21Å; I614-L619 HydrophobicContact CB-CG 4.13Å; I614-L619 HydrophobicContact CD1-CD2 4.22Å; I614-L619 HydrophobicContact CG2-CD2 3.87Å; I614-L619 HydrophobicContact CG2-CG 3.67Å; I614-F666 PolarHBondContact N-O 3.29Å; I614-F666 PolarHBondContact O-N 3.17Å
615S97.2Very high94.3Very high16 Ų1668.6 Ų68.611%0.11233%0.334CS..EExtended strand (participates in β ladder)trans-68.8156.9175.762.80000112.2E617 N618 L619 T664S615-E617 VanDerWaalsContact C-N 3.25Å; S615-E617 PolarHBondContact O-N 3.2Å; S615-N618 PolarHBondContact O-N 2.95Å; S615-N618 WeakPolarHBondContact OG-CB 3.45Å; S615-N618 PolarHBondContact OG-N 3.4Å; S615-N618 PolarHBondContact OG-ND2 3.12Å; S615-L619 WeakPolarHBondContact O-CG 3.28Å; S615-L619 PolarHBondContact O-N 3.19Å; S615-T664 CarbonylContact C-O 3.52Å; S615-T664 WeakPolarHBondContact CA-O 3.43Å
616F97.4Very high94Very high0 Ų070.6 Ų70.60%035%0.346CS..Hα-helixtrans-52.9-45.5172-177.7-90.9000111.5N618 L619 K620 D627 L630 R631 L634 F660 T661 E662 T664 F666F616-N618 PolarHBondContact O-N 3.01Å; F616-L619 PolarHBondContact O-N 3.06Å; F616-K620 HydrophobicContact CE1-CD 4.29Å; F616-K620 WeakPolarHBondContact O-CB 3.44Å; F616-K620 PolarHBondContact O-N 2.71Å; F616-D627 WeakPolarHBondContact CE1-OD1 3.02Å; F616-L630 HydrophobicContact CD2-CD2 4.21Å; F616-L630 HydrophobicContact CD2-CG 4.47Å; F616-L630 HydrophobicContact CE1-CD2 4.24Å; F616-L630 HydrophobicContact CE2-CB 4.36Å; F616-L630 HydrophobicContact CE2-CD2 3.77Å; F616-L630 HydrophobicContact CE2-CG 3.82Å; F616-L630 HydrophobicContact CZ-CB 4.33Å; F616-L630 HydrophobicContact CZ-CD2 3.78Å; F616-L630 HydrophobicContact CZ-CG 4.13Å; F616-R631 HydrophobicContact CE2-CB 4.5Å; F616-R631 HydrophobicContact CE2-CG 3.56Å; F616-R631 HydrophobicContact CZ-CG 3.61Å; F616-L634 HydrophobicContact CD2-CD1 3.68Å; F616-L634 HydrophobicContact CE2-CD1 3.93Å; F616-F660 HydrophobicContact CD2-CB 4.37Å; F616-T661 VanDerWaalsContact CB-O 3.25Å; F616-T661 WeakPolarHBondContact CB-O 3.44Å; F616-E662 WeakPolarHBondContact CD1-OE2 3.46Å; F616-E662 PolarHBondContact N-O 3.24Å; F616-T664 PolarHBondContact N-O 3.37Å; F616-F666 HydrophobicContact CB-CE2 4.07Å; F616-F666 HydrophobicContact CD2-CE2 4.23Å
617E96.7Very high93.8Very high103 Ų10372.8 Ų72.848%0.48136%0.358SS..Hα-helixtrans-56.5-47.5177.5-175.6178.9-165.600112S615 L619 K620 L621 E662S615-E617 VanDerWaalsContact C-N 3.25Å; S615-E617 PolarHBondContact O-N 3.2Å; E617-L619 PolarHBondContact O-N 2.98Å; E617-K620 WeakPolarHBondContact O-CB 3.36Å; E617-K620 PolarHBondContact O-N 3.04Å; E617-L621 WeakPolarHBondContact O-CG 3.33Å; E617-L621 PolarHBondContact O-N 3.35Å; E617-E662 WeakPolarHBondContact CA-OE2 3.48Å; E617-E662 HydrophobicContact CB-CB 4.27Å; E617-E662 WeakPolarHBondContact CB-OE2 3.14Å; E617-E662 PolarHBondContact N-O 2.76Å
618N96.2Very high93.6Very high77 Ų7770.3 Ų70.341%0.41235%0.352SS..Hα-helixtrans-69-34.8-179.5-76.8-24.4000112.4I614 S615 F616 K620 L621 A622I614-N618 HydrophobicContact CG2-CB 3.63Å; S615-N618 PolarHBondContact O-N 2.95Å; S615-N618 WeakPolarHBondContact OG-CB 3.45Å; S615-N618 PolarHBondContact OG-N 3.4Å; S615-N618 PolarHBondContact OG-ND2 3.12Å; F616-N618 PolarHBondContact O-N 3.01Å; N618-K620 VanDerWaalsContact C-N 3.35Å; N618-L621 PolarHBondContact O-N 3.26Å; N618-A622 VanDerWaalsContact O-CB 3.3Å; N618-A622 WeakPolarHBondContact O-CB 3.48Å; N618-A622 PolarHBondContact O-N 2.96Å
619L96Very high93.5Very high0 Ų062.5 Ų62.50%032%0.315CS..Hα-helixtrans-67.6-37173.7-71.7168.6000111.7A605 W606 I614 S615 F616 E617 A622 T623 L630 L634 F666A605-L619 HydrophobicContact CB-CD2 3.78Å; W606-L619 HydrophobicContact CH2-CD1 3.78Å; W606-L619 HydrophobicContact CH2-CD2 3.7Å; W606-L619 HydrophobicContact CH2-CG 4.37Å; W606-L619 HydrophobicContact CZ2-CD1 4.37Å; W606-L619 HydrophobicContact CZ2-CD2 4.32Å; W606-L619 HydrophobicContact CZ3-CD2 3.91Å; I614-L619 HydrophobicContact CB-CD2 4.21Å; I614-L619 HydrophobicContact CB-CG 4.13Å; I614-L619 HydrophobicContact CD1-CD2 4.22Å; I614-L619 HydrophobicContact CG2-CD2 3.87Å; I614-L619 HydrophobicContact CG2-CG 3.67Å; S615-L619 WeakPolarHBondContact O-CG 3.28Å; S615-L619 PolarHBondContact O-N 3.19Å; F616-L619 PolarHBondContact O-N 3.06Å; E617-L619 PolarHBondContact O-N 2.98Å; L619-A622 PolarHBondContact O-N 3.28Å; L619-T623 WeakPolarHBondContact O-CB 3.14Å; L619-T623 WeakPolarHBondContact O-CG2 3.33Å; L619-T623 PolarHBondContact O-N 3.4Å; L619-T623 PolarHBondContact O-OG1 3.48Å; L619-L630 HydrophobicContact CB-CD2 4.4Å; L619-L634 HydrophobicContact CD1-CD1 4.26Å; L619-L634 HydrophobicContact CD1-CD2 3.9Å; L619-F666 HydrophobicContact CD1-CB 4.05Å; L619-F666 HydrophobicContact CD1-CD2 3.76Å; L619-F666 HydrophobicContact CD1-CG 4.07Å
620K95.3Very high93.5Very high69 Ų6958.8 Ų58.830%0.330%0.301SS..Hα-helixtrans-62.9-44.4174.7-173-179178.1178.10111.8F616 E617 N618 E624 D627 L630 E662F616-K620 HydrophobicContact CE1-CD 4.29Å; F616-K620 WeakPolarHBondContact O-CB 3.44Å; F616-K620 PolarHBondContact O-N 2.71Å; E617-K620 WeakPolarHBondContact O-CB 3.36Å; E617-K620 PolarHBondContact O-N 3.04Å; N618-K620 VanDerWaalsContact C-N 3.35Å; K620-E624 WeakPolarHBondContact O-CA 3.12Å; K620-E624 PolarHBondContact O-N 2.83Å; K620-D627 IonicContact NZ-OD1 2.93Å; K620-L630 VanDerWaalsContact CA-CD2 3.47Å; K620-L630 HydrophobicContact CB-CD2 3.54Å; K620-L630 HydrophobicContact CG-CD2 4.17Å; K620-E662 IonicContact NZ-OE1 3.79Å
621L94.5Very high93.5Very high121 Ų12157 Ų5763%0.63429%0.285SS*.Hα-helixtrans-64.7-44174.3-68.6172.2000112E617 N618 T623E617-L621 WeakPolarHBondContact O-CG 3.33Å; E617-L621 PolarHBondContact O-N 3.35Å; N618-L621 PolarHBondContact O-N 3.26Å; L621-T623 PolarHBondContact O-N 3.3Å
622A93.1Very high93.3Very high46 Ų4650.6 Ų50.638%0.3826%0.261SS..Hα-helixtrans-69.3-32.2-176.700000113.7N618 L619N618-A622 VanDerWaalsContact O-CB 3.3Å; N618-A622 WeakPolarHBondContact O-CB 3.48Å; N618-A622 PolarHBondContact O-N 2.96Å; L619-A622 PolarHBondContact O-N 3.28Å
623T93.4Very high93.1Very high2 Ų246.1 Ų46.11%0.01224%0.241CC..Hα-helixtrans-102-14.7-17661.20000113.8V545 S546 A601 V602 L619 L621 L625V545-T623 WeakPolarHBondContact CA-O 3.4Å; S546-T623 PolarHBondContact N-O 2.96Å; A601-T623 HydrophobicContact CB-CG2 4.34Å; V602-T623 HydrophobicContact CG2-CG2 4.01Å; L619-T623 WeakPolarHBondContact O-CB 3.14Å; L619-T623 WeakPolarHBondContact O-CG2 3.33Å; L619-T623 PolarHBondContact O-N 3.4Å; L619-T623 PolarHBondContact O-OG1 3.48Å; L621-T623 PolarHBondContact O-N 3.3Å; T623-L625 PolarHBondContact O-N 3.01Å
624E94.3Very high93Very high119 Ų11941 Ų4156%0.55622%0.218SC*.  trans54.515-172.6-64.6-173.6176.600115S546 K620S546-E624 VanDerWaalsContact OG-CG 3.29Å; S546-E624 WeakPolarHBondContact OG-CG 3.39Å; K620-E624 WeakPolarHBondContact O-CA 3.12Å; K620-E624 PolarHBondContact O-N 2.83Å
625L91.5Very high92.8Very high3 Ų343.9 Ų43.92%0.01623%0.229CC..  trans-69.2138.4179.2-74.5171.6000110.7V543 V545 F598 V602 T623 L630V543-L625 HydrophobicContact CG1-CD2 4.31Å; V545-L625 HydrophobicContact CB-CD2 3.89Å; V545-L625 HydrophobicContact CG2-CD2 3.87Å; V545-L625 HydrophobicContact CG2-CG 4.18Å; F598-L625 HydrophobicContact CB-CD1 4.06Å; F598-L625 HydrophobicContact CB-CD2 4.34Å; F598-L625 HydrophobicContact CD1-CD2 3.62Å; F598-L625 HydrophobicContact CD2-CD2 4.1Å; F598-L625 HydrophobicContact CE1-CD2 3.83Å; F598-L625 HydrophobicContact CE2-CD2 4.28Å; F598-L625 HydrophobicContact CG-CD1 4.38Å; F598-L625 HydrophobicContact CG-CD2 3.77Å; F598-L625 HydrophobicContact CZ-CD2 4.17Å; V602-L625 HydrophobicContact CG2-CD1 4.13Å; T623-L625 PolarHBondContact O-N 3.01Å; L625-L630 HydrophobicContact CB-CB 4.06Å; L625-L630 HydrophobicContact CD1-CD1 4.25Å
626P90Very high92.4Very high59 Ų5944.6 Ų44.638%0.38323%0.234SC..  trans-55.4144170.1-24.833.9000111.2V543 A628 E629 L630V543-P626 HydrophobicContact CG1-CG 4Å; P626-A628 VanDerWaalsContact C-N 3.27Å; P626-A628 PolarHBondContact O-N 2.91Å; P626-A628 VanDerWaalsContact O-N 3.12Å; P626-E629 HydrophobicContact CB-CB 4.5Å; P626-E629 HydrophobicContact CB-CG 4.25Å; P626-E629 HydrophobicContact CG-CG 4.28Å; P626-E629 WeakPolarHBondContact O-CA 3.4Å; P626-E629 WeakPolarHBondContact O-CB 3.25Å; P626-E629 PolarHBondContact O-N 2.76Å; P626-L630 PolarHBondContact O-N 3.49Å
627D90.5Very high92.2Very high53 Ų5344.7 Ų44.728%0.28324%0.235SC..Hα-helixtrans-48.1-46.6-175.4175.893.8000113.1F616 K620 E629 L630 R631F616-D627 WeakPolarHBondContact CE1-OD1 3.02Å; K620-D627 IonicContact NZ-OD1 2.93Å; D627-E629 PolarHBondContact O-N 3.38Å; D627-L630 PolarHBondContact O-N 3.15Å; D627-R631 VanDerWaalsContact CG-NE 3.26Å; D627-R631 VanDerWaalsContact O-CG 3.25Å; D627-R631 WeakPolarHBondContact O-CG 3.49Å; D627-R631 PolarHBondContact O-N 3.07Å; D627-R631 IonicContact OD1-CZ 2.66Å; D627-R631 IonicContact OD1-NE 3.42Å; D627-R631 PolarHBondContact OD1-NE 2.95Å; D627-R631 IonicContact OD1-NH2 3.33Å; D627-R631 PolarHBondContact OD1-NH2 3.3Å; D627-R631 WeakPolarHBondContact OD2-CD 3.44Å; D627-R631 IonicContact OD2-CZ 3.97Å; D627-R631 IonicContact OD2-NE 3.57Å; D627-R631 PolarHBondContact OD2-NE 2.5Å; D627-R631 IonicContact OD2-NH2 3.22Å
628A86.8Confident92Very high52 Ų5240.2 Ų40.243%0.4321%0.214SC..Hα-helixtrans-64.3-37.2178.200000113.5P626 R632P626-A628 VanDerWaalsContact C-N 3.27Å; P626-A628 PolarHBondContact O-N 2.91Å; P626-A628 VanDerWaalsContact O-N 3.12Å; A628-R632 WeakPolarHBondContact O-CG 3.33Å; A628-R632 PolarHBondContact O-N 2.7Å; A628-R632 PolarHBondContact O-NE 3.03Å
629E86.5Confident91.7Very high32 Ų3238 Ų3815%0.1521%0.207CC..Hα-helixtrans-71.8-44177.4-65.2-60.3160.600111.2V543 F598 P626 D627 R632 T633V543-E629 HydrophobicContact CG1-CG 4.22Å; F598-E629 HydrophobicContact CE2-CG 4.46Å; P626-E629 HydrophobicContact CB-CB 4.5Å; P626-E629 HydrophobicContact CB-CG 4.25Å; P626-E629 HydrophobicContact CG-CG 4.28Å; P626-E629 WeakPolarHBondContact O-CA 3.4Å; P626-E629 WeakPolarHBondContact O-CB 3.25Å; P626-E629 PolarHBondContact O-N 2.76Å; D627-E629 PolarHBondContact O-N 3.38Å; E629-R632 PolarHBondContact O-N 2.99Å; E629-R632 IonicContact OE1-CZ 3.91Å; E629-R632 IonicContact OE1-NH2 3.45Å; E629-R632 PolarHBondContact OE1-NH2 3.24Å; E629-R632 IonicContact OE2-CZ 3.46Å; E629-R632 IonicContact OE2-NE 2.72Å; E629-R632 IonicContact OE2-NH2 3.27Å; E629-R632 PolarHBondContact OE2-NH2 2.67Å; E629-T633 VanDerWaalsContact O-CB 3.32Å; E629-T633 WeakPolarHBondContact O-CB 3.35Å; E629-T633 PolarHBondContact O-N 3.24Å; E629-T633 PolarHBondContact O-OG1 3.18Å
630L92.7Very high91.3Very high0 Ų039.2 Ų39.20%021%0.212CC..Hα-helixtrans-62.2-46.3179.5-179.361.3000111.5V602 F616 L619 K620 L625 P626 D627 R632 T633 L634V602-L630 HydrophobicContact CG2-CD1 3.78Å; F616-L630 HydrophobicContact CD2-CD2 4.21Å; F616-L630 HydrophobicContact CD2-CG 4.47Å; F616-L630 HydrophobicContact CE1-CD2 4.24Å; F616-L630 HydrophobicContact CE2-CB 4.36Å; F616-L630 HydrophobicContact CE2-CD2 3.77Å; F616-L630 HydrophobicContact CE2-CG 3.82Å; F616-L630 HydrophobicContact CZ-CB 4.33Å; F616-L630 HydrophobicContact CZ-CD2 3.78Å; F616-L630 HydrophobicContact CZ-CG 4.13Å; L619-L630 HydrophobicContact CB-CD2 4.4Å; K620-L630 VanDerWaalsContact CA-CD2 3.47Å; K620-L630 HydrophobicContact CB-CD2 3.54Å; K620-L630 HydrophobicContact CG-CD2 4.17Å; L625-L630 HydrophobicContact CB-CB 4.06Å; L625-L630 HydrophobicContact CD1-CD1 4.25Å; P626-L630 PolarHBondContact O-N 3.49Å; D627-L630 PolarHBondContact O-N 3.15Å; L630-R632 VanDerWaalsContact C-N 3.33Å; L630-R632 PolarHBondContact O-N 3.24Å; L630-T633 PolarHBondContact O-N 2.85Å; L630-L634 HydrophobicContact CD1-CD1 3.83Å; L630-L634 HydrophobicContact CD1-CG 3.99Å; L630-L634 HydrophobicContact CD2-CD1 4.42Å; L630-L634 HydrophobicContact CG-CD1 3.77Å; L630-L634 HydrophobicContact CG-CG 4.36Å; L630-L634 WeakPolarHBondContact O-CB 3.38Å; L630-L634 WeakPolarHBondContact O-CG 3.37Å; L630-L634 PolarHBondContact O-N 3.24Å
631R92.3Very high90.7Very high35 Ų3542 Ų4213%0.13224%0.237CC..Hα-helixtrans-55.5-46.7177-73.6171.8-169.3-72.8-13.1112.2F616 D627 W635 P657 F660F616-R631 HydrophobicContact CE2-CB 4.5Å; F616-R631 HydrophobicContact CE2-CG 3.56Å; F616-R631 HydrophobicContact CZ-CG 3.61Å; D627-R631 VanDerWaalsContact CG-NE 3.26Å; D627-R631 VanDerWaalsContact O-CG 3.25Å; D627-R631 WeakPolarHBondContact O-CG 3.49Å; D627-R631 PolarHBondContact O-N 3.07Å; D627-R631 IonicContact OD1-CZ 2.66Å; D627-R631 IonicContact OD1-NE 3.42Å; D627-R631 PolarHBondContact OD1-NE 2.95Å; D627-R631 IonicContact OD1-NH2 3.33Å; D627-R631 PolarHBondContact OD1-NH2 3.3Å; D627-R631 WeakPolarHBondContact OD2-CD 3.44Å; D627-R631 IonicContact OD2-CZ 3.97Å; D627-R631 IonicContact OD2-NE 3.57Å; D627-R631 PolarHBondContact OD2-NE 2.5Å; D627-R631 IonicContact OD2-NH2 3.22Å; R631-W635 VanDerWaalsContact O-CB 3.3Å; R631-W635 WeakPolarHBondContact O-CB 3.29Å; R631-W635 PolarHBondContact O-N 2.94Å; R631-P657 HydrophobicContact CB-CB 4.19Å; R631-P657 WeakPolarHBondContact CD-O 3.45Å; R631-P657 WeakPolarHBondContact CG-O 3.41Å; R631-F660 HydrophobicContact CG-CD2 4.48Å; R631-F660 PolarHBondContact NH1-O 2.88Å
632R87Confident90Very high60 Ų6045.2 Ų45.223%0.22625%0.246CC..Hα-helixtrans-67.3-41.2178.1-71.6-172.1-61.6-141.67.2112A628 E629 L630 W635 S636A628-R632 WeakPolarHBondContact O-CG 3.33Å; A628-R632 PolarHBondContact O-N 2.7Å; A628-R632 PolarHBondContact O-NE 3.03Å; E629-R632 PolarHBondContact O-N 2.99Å; E629-R632 IonicContact OE1-CZ 3.91Å; E629-R632 IonicContact OE1-NH2 3.45Å; E629-R632 PolarHBondContact OE1-NH2 3.24Å; E629-R632 IonicContact OE2-CZ 3.46Å; E629-R632 IonicContact OE2-NE 2.72Å; E629-R632 IonicContact OE2-NH2 3.27Å; E629-R632 PolarHBondContact OE2-NH2 2.67Å; L630-R632 VanDerWaalsContact C-N 3.33Å; L630-R632 PolarHBondContact O-N 3.24Å; R632-W635 PolarHBondContact O-N 3.48Å; R632-S636 PolarHBondContact O-N 2.89Å
633T91.1Very high89.7Confident10 Ų1044 Ų446%0.06123%0.233CC..Hα-helixtrans-61.4-49.1178.2-590000110.4F598 Q599 V602 E629 L630 W635 S636 L637F598-T633 HydrophobicContact CB-CG2 4Å; Q599-T633 HydrophobicContact CB-CG2 4.4Å; Q599-T633 HydrophobicContact CG-CG2 3.92Å; V602-T633 HydrophobicContact CB-CG2 4.4Å; V602-T633 HydrophobicContact CG2-CG2 3.78Å; E629-T633 VanDerWaalsContact O-CB 3.32Å; E629-T633 WeakPolarHBondContact O-CB 3.35Å; E629-T633 PolarHBondContact O-N 3.24Å; E629-T633 PolarHBondContact O-OG1 3.18Å; L630-T633 PolarHBondContact O-N 2.85Å; T633-W635 PolarHBondContact O-N 3.23Å; T633-S636 WeakPolarHBondContact O-CB 3.09Å; T633-S636 PolarHBondContact O-N 2.67Å; T633-S636 PolarHBondContact O-OG 3.44Å; T633-L637 PolarHBondContact O-N 2.91Å
634L94.4Very high89.4Confident0 Ų051.8 Ų51.80%027%0.267CS..Hα-helixtrans-62.5-44.6176.4-72.5167.3000111.9V602 F616 L619 L630 S636 L637 V638 L648 F660 F666V602-L634 HydrophobicContact CG1-CD2 3.67Å; F616-L634 HydrophobicContact CD2-CD1 3.68Å; F616-L634 HydrophobicContact CE2-CD1 3.93Å; L619-L634 HydrophobicContact CD1-CD1 4.26Å; L619-L634 HydrophobicContact CD1-CD2 3.9Å; L630-L634 HydrophobicContact CD1-CD1 3.83Å; L630-L634 HydrophobicContact CD1-CG 3.99Å; L630-L634 HydrophobicContact CD2-CD1 4.42Å; L630-L634 HydrophobicContact CG-CD1 3.77Å; L630-L634 HydrophobicContact CG-CG 4.36Å; L630-L634 WeakPolarHBondContact O-CB 3.38Å; L630-L634 WeakPolarHBondContact O-CG 3.37Å; L630-L634 PolarHBondContact O-N 3.24Å; L634-S636 PolarHBondContact O-N 2.64Å; L634-L637 WeakPolarHBondContact O-CA 3.45Å; L634-L637 WeakPolarHBondContact O-CB 3.33Å; L634-L637 PolarHBondContact O-N 3.12Å; L634-V638 WeakPolarHBondContact O-CG2 3.41Å; L634-V638 PolarHBondContact O-N 3.33Å; L634-L648 HydrophobicContact CD2-CD1 4.19Å; L634-F660 HydrophobicContact CB-CE2 4.17Å; L634-F666 HydrophobicContact CB-CE1 4Å; L634-F666 HydrophobicContact CB-CZ 4.27Å; L634-F666 HydrophobicContact CD1-CD2 4.31Å; L634-F666 HydrophobicContact CD1-CE1 4.16Å; L634-F666 HydrophobicContact CD1-CE2 3.82Å; L634-F666 HydrophobicContact CD1-CZ 3.74Å; L634-F666 HydrophobicContact CD2-CD1 4.01Å; L634-F666 HydrophobicContact CD2-CE1 4.18Å; L634-F666 HydrophobicContact CD2-CG 4.22Å; L634-F666 HydrophobicContact CG-CE1 4.35Å; L634-F666 HydrophobicContact CG-CZ 4.41Å
635W92.3Very high89.3Confident64 Ų6450.4 Ų50.424%0.24226%0.257CS..Hα-helixtrans-56.4-40.2176-167.3-99.7000112.4R631 R632 T633 L637 V638 A639 V654 N655 P657 F660R631-W635 VanDerWaalsContact O-CB 3.3Å; R631-W635 WeakPolarHBondContact O-CB 3.29Å; R631-W635 PolarHBondContact O-N 2.94Å; R632-W635 PolarHBondContact O-N 3.48Å; T633-W635 PolarHBondContact O-N 3.23Å; W635-L637 PolarHBondContact O-N 2.73Å; W635-V638 HydrophobicContact CE3-CG2 4.26Å; W635-V638 PolarHBondContact O-N 2.7Å; W635-A639 HydrophobicContact CD2-CB 3.99Å; W635-A639 HydrophobicContact CG-CB 4.38Å; W635-A639 HydrophobicContact CH2-CB 4.34Å; W635-A639 HydrophobicContact CZ2-CB 3.8Å; W635-A639 WeakPolarHBondContact O-CA 3.45Å; W635-A639 WeakPolarHBondContact O-CB 3.35Å; W635-A639 PolarHBondContact O-N 2.7Å; W635-V654 HydrophobicContact CZ3-CG2 4.18Å; W635-N655 VanDerWaalsContact CH2-C 3.41Å; W635-N655 WeakPolarHBondContact CH2-O 3.45Å; W635-P657 HydrophobicContact CB-CB 3.88Å; W635-P657 HydrophobicContact CB-CG 4.48Å; W635-P657 HydrophobicContact CD2-CB 4.21Å; W635-P657 HydrophobicContact CD2-CG 4.36Å; W635-P657 HydrophobicContact CE3-CB 4.3Å; W635-P657 HydrophobicContact CG-CB 4.03Å; W635-P657 HydrophobicContact CG-CG 4.2Å; W635-F660 HydrophobicContact CB-CE2 4.46Å; W635-F660 HydrophobicContact CE3-CE1 4.26Å; W635-F660 AromaticContact CE3-CE2 3.92Å; W635-F660 HydrophobicContact CE3-CE2 3.92Å; W635-F660 AromaticContact CE3-CZ 3.51Å; W635-F660 HydrophobicContact CE3-CZ 3.51Å; W635-F660 HydrophobicContact CZ3-CE1 4.29Å; W635-F660 AromaticContact CZ3-CZ 3.97Å; W635-F660 HydrophobicContact CZ3-CZ 3.97Å
636S89.1Confident89.4Confident32 Ų3252 Ų5222%0.22426%0.264CS..Hα-helixtrans-64.3-21.1176.880.10000114.1Q599 R632 T633 L634Q599-S636 PolarHBondContact NE2-OG 2.87Å; R632-S636 PolarHBondContact O-N 2.89Å; T633-S636 WeakPolarHBondContact O-CB 3.09Å; T633-S636 PolarHBondContact O-N 2.67Å; T633-S636 PolarHBondContact O-OG 3.44Å; L634-S636 PolarHBondContact O-N 2.64Å
637L92.7Very high89.6Confident1 Ų149.2 Ų49.21%0.00525%0.246CC..Hα-helixtrans-96.9-25179.9-64.4172.4000113.2Q599 V602 L603 T633 L634 W635 V647 L648 L688Q599-L637 HydrophobicContact CB-CD2 4.28Å; Q599-L637 HydrophobicContact CG-CD1 4.42Å; Q599-L637 HydrophobicContact CG-CD2 4.05Å; Q599-L637 HydrophobicContact CG-CG 4.22Å; V602-L637 HydrophobicContact CB-CD1 4.33Å; V602-L637 HydrophobicContact CG1-CD1 3.83Å; L603-L637 HydrophobicContact CD1-CD2 4.15Å; L603-L637 HydrophobicContact CD2-CD1 4.16Å; L603-L637 HydrophobicContact CD2-CD2 4.5Å; L603-L637 HydrophobicContact CG-CD1 4.11Å; L603-L637 HydrophobicContact CG-CD2 4.47Å; T633-L637 PolarHBondContact O-N 2.91Å; L634-L637 WeakPolarHBondContact O-CA 3.45Å; L634-L637 WeakPolarHBondContact O-CB 3.33Å; L634-L637 PolarHBondContact O-N 3.12Å; W635-L637 PolarHBondContact O-N 2.73Å; L637-V647 PolarHBondContact O-N 3.46Å; L637-L648 HydrophobicContact CB-CB 4.41Å; L637-L648 HydrophobicContact CB-CD1 3.8Å; L637-L648 HydrophobicContact CB-CG 4.04Å; L637-L648 HydrophobicContact CD1-CD1 3.79Å; L637-L648 HydrophobicContact CG-CD1 4.44Å; L637-L648 PolarHBondContact O-N 3.36Å; L637-L688 HydrophobicContact CD2-CD1 4.37Å
638V93.4Very high89.8Confident9 Ų946.7 Ų46.76%0.05523%0.233CC..Hα-helixtrans-101.2-17.2178.8-57.20000114.5L634 W635 Q646 L648 Y650 F660 F666L634-V638 WeakPolarHBondContact O-CG2 3.41Å; L634-V638 PolarHBondContact O-N 3.33Å; W635-V638 HydrophobicContact CE3-CG2 4.26Å; W635-V638 PolarHBondContact O-N 2.7Å; V638-Q646 WeakPolarHBondContact O-CG 3.43Å; V638-L648 HydrophobicContact CG1-CB 3.65Å; V638-Y650 HydrophobicContact CB-CD1 3.59Å; V638-Y650 HydrophobicContact CB-CE1 3.89Å; V638-Y650 HydrophobicContact CG1-CD1 3.75Å; V638-Y650 HydrophobicContact CG1-CG 4.34Å; V638-Y650 HydrophobicContact CG2-CD1 3.84Å; V638-Y650 HydrophobicContact CG2-CE1 3.86Å; V638-F660 HydrophobicContact CG2-CZ 4.03Å; V638-F666 HydrophobicContact CG1-CD1 4.02Å; V638-F666 HydrophobicContact CG1-CE1 4.16Å
639A88.9Confident90.3Very high31 Ų3148 Ų4826%0.25623%0.232SC..  trans-139.646.7-17300000112.1W635 P641W635-A639 HydrophobicContact CD2-CB 3.99Å; W635-A639 HydrophobicContact CG-CB 4.38Å; W635-A639 HydrophobicContact CH2-CB 4.34Å; W635-A639 HydrophobicContact CZ2-CB 3.8Å; W635-A639 WeakPolarHBondContact O-CA 3.45Å; W635-A639 WeakPolarHBondContact O-CB 3.35Å; W635-A639 PolarHBondContact O-N 2.7Å; A639-P641 VanDerWaalsContact O-CD 3.31Å; A639-P641 WeakPolarHBondContact O-CD 3.42Å
640F87.4Confident90.8Very high25 Ų2547.7 Ų47.711%0.1123%0.229CC..  trans-77.6115.9177.5-163.5-95.5000111.1K642 L643 Q646 N687 L688F640-K642 VanDerWaalsContact C-N 3.27Å; F640-K642 HydrophobicContact CD1-CB 4.06Å; F640-K642 HydrophobicContact CE1-CB 3.8Å; F640-K642 HydrophobicContact CE1-CD 4.36Å; F640-K642 HydrophobicContact CE1-CG 4.22Å; F640-K642 PolarHBondContact O-N 2.87Å; F640-K642 VanDerWaalsContact O-N 3.09Å; F640-L643 HydrophobicContact CB-CB 4.46Å; F640-L643 HydrophobicContact CB-CD1 4.14Å; F640-L643 HydrophobicContact CB-CG 4.49Å; F640-L643 HydrophobicContact CD1-CB 4.3Å; F640-L643 HydrophobicContact CD1-CD1 3.91Å; F640-L643 HydrophobicContact CD1-CG 3.75Å; F640-L643 HydrophobicContact CE1-CG 4.45Å; F640-L643 HydrophobicContact CG-CD1 4.25Å; F640-L643 HydrophobicContact CG-CG 4.49Å; F640-L643 PolarHBondContact O-N 3.22Å; F640-L643 VanDerWaalsContact O-N 3.1Å; F640-Q646 PolarHBondContact O-NE2 3.42Å; F640-N687 WeakPolarHBondContact CZ-O 3.32Å; F640-L688 HydrophobicContact CD1-CD2 4.44Å; F640-L688 HydrophobicContact CD2-CD2 4.26Å; F640-L688 HydrophobicContact CE2-CD2 4.38Å; F640-L688 HydrophobicContact CG-CD2 4.28Å
641P82.2Confident90.9Very high127 Ų12751.6 Ų51.683%0.82525%0.248SC*.THydrogen-bonded Turntrans-62.4-26.8-167.8-2735.4000115.6A639 L643A639-P641 VanDerWaalsContact O-CD 3.31Å; A639-P641 WeakPolarHBondContact O-CD 3.42Å; P641-L643 VanDerWaalsContact C-N 3.34Å
642K80.3Confident91Very high189 Ų18953.9 Ų53.982%0.82227%0.267SS*.THydrogen-bonded Turntrans-87.2-2.7-177.4-56.7-177.5177179.80113.6F640F640-K642 VanDerWaalsContact C-N 3.27Å; F640-K642 HydrophobicContact CD1-CB 4.06Å; F640-K642 HydrophobicContact CE1-CB 3.8Å; F640-K642 HydrophobicContact CE1-CD 4.36Å; F640-K642 HydrophobicContact CE1-CG 4.22Å; F640-K642 PolarHBondContact O-N 2.87Å; F640-K642 VanDerWaalsContact O-N 3.09Å
643L86.2Confident91.3Very high21 Ų2157.7 Ų57.711%0.1129%0.287CS..  trans-109.3128.3-177.7-71.5176.3000110.6F640 P641 Q646 F672 L674 I686 L688F640-L643 HydrophobicContact CB-CB 4.46Å; F640-L643 HydrophobicContact CB-CD1 4.14Å; F640-L643 HydrophobicContact CB-CG 4.49Å; F640-L643 HydrophobicContact CD1-CB 4.3Å; F640-L643 HydrophobicContact CD1-CD1 3.91Å; F640-L643 HydrophobicContact CD1-CG 3.75Å; F640-L643 HydrophobicContact CE1-CG 4.45Å; F640-L643 HydrophobicContact CG-CD1 4.25Å; F640-L643 HydrophobicContact CG-CG 4.49Å; F640-L643 PolarHBondContact O-N 3.22Å; F640-L643 VanDerWaalsContact O-N 3.1Å; P641-L643 VanDerWaalsContact C-N 3.34Å; L643-Q646 PolarHBondContact O-NE2 3.01Å; L643-F672 HydrophobicContact CD1-CE2 4.2Å; L643-L674 HydrophobicContact CD2-CD2 3.92Å; L643-I686 HydrophobicContact CD1-CG2 4.4Å; L643-I686 HydrophobicContact CD2-CG2 4.33Å; L643-L688 HydrophobicContact CD1-CD2 3.65Å
644K87.6Confident91.4Very high166 Ų16658.4 Ų58.472%0.72229%0.291SS*.SBendtrans-72.9-32.8173.9-69.1-170.9177.2-172.30112.4I675K644-I675 HydrophobicContact CB-CD1 4.05Å; K644-I675 HydrophobicContact CD-CB 4.21Å; K644-I675 HydrophobicContact CD-CD1 4.06Å; K644-I675 HydrophobicContact CD-CG2 4.28Å
645R92.1Very high91.1Very high89 Ų8965.9 Ų65.934%0.33633%0.331SS..SBendtrans-120.4129.3175.2-64.8-174.8-179.5-160.6-2.3107.8E671 F672 I675R645-E671 WeakPolarHBondContact CD-O 3.25Å; R645-E671 PolarHBondContact NH1-O 3.18Å; R645-F672 HydrophobicContact CB-CD2 4.3Å; R645-F672 VanDerWaalsContact O-CD2 3.28Å; R645-F672 WeakPolarHBondContact O-CD2 3.35Å; R645-F672 WeakPolarHBondContact O-CE2 3.29Å; R645-I675 HydrophobicContact CG-CD1 4.4Å
646Q93.7Very high90.9Very high37 Ų3764.4 Ų64.417%0.17333%0.331CS..  trans-87.3155.2-173.1-58.4-65.8-21.900110.5V638 F640 L643 L648 N669 F672V638-Q646 WeakPolarHBondContact O-CG 3.43Å; F640-Q646 PolarHBondContact O-NE2 3.42Å; L643-Q646 PolarHBondContact O-NE2 3.01Å; Q646-L648 WeakPolarHBondContact CB-O 3.49Å; Q646-N669 WeakPolarHBondContact O-CB 3.45Å; Q646-N669 PolarHBondContact O-ND2 3.03Å; Q646-F672 WeakPolarHBondContact O-CD2 3.49Å
647V94.2Very high90.8Very high0 Ų064.4 Ų64.40%033%0.33CS..SBendtrans-71.2-41.4-176.6178.80000110.3F584 L593 L603 L637 N669 F672 L688F584-V647 HydrophobicContact CD2-CG1 4.33Å; F584-V647 HydrophobicContact CE2-CG1 3.85Å; F584-V647 HydrophobicContact CZ-CG1 4.09Å; L593-V647 HydrophobicContact CD1-CG1 4.19Å; L593-V647 HydrophobicContact CD1-CG2 4.49Å; L603-V647 HydrophobicContact CD2-CG1 4Å; L637-V647 PolarHBondContact O-N 3.46Å; V647-N669 VanDerWaalsContact O-CB 3.29Å; V647-N669 WeakPolarHBondContact O-CB 3.12Å; V647-N669 PolarHBondContact O-N 3.15Å; V647-F672 HydrophobicContact CG2-CD2 4.39Å; V647-F672 HydrophobicContact CG2-CE2 3.94Å; V647-F672 HydrophobicContact CG2-CZ 4.14Å; V647-L688 HydrophobicContact CG2-CD1 3.79Å; V647-L688 HydrophobicContact CG2-CD2 4.45Å
648L95.9Very high90.6Very high1 Ų172.4 Ų72.41%0.00537%0.365CS..EExtended strand (participates in β ladder)trans-111.2150.3174.2-62.9-177.8000110.5V602 L603 W606 L634 L637 V638 Q646 S667 V668V602-L648 HydrophobicContact CG1-CD1 4.42Å; L603-L648 HydrophobicContact CD2-CD1 4.43Å; L603-L648 HydrophobicContact CD2-CD2 4.07Å; L603-L648 HydrophobicContact CD2-CG 4.28Å; W606-L648 HydrophobicContact CE3-CD2 4.46Å; W606-L648 HydrophobicContact CH2-CD1 3.97Å; W606-L648 HydrophobicContact CH2-CD2 4.21Å; W606-L648 HydrophobicContact CZ3-CD1 4.06Å; W606-L648 HydrophobicContact CZ3-CD2 4.17Å; L634-L648 HydrophobicContact CD2-CD1 4.19Å; L637-L648 HydrophobicContact CB-CB 4.41Å; L637-L648 HydrophobicContact CB-CD1 3.8Å; L637-L648 HydrophobicContact CB-CG 4.04Å; L637-L648 HydrophobicContact CD1-CD1 3.79Å; L637-L648 HydrophobicContact CG-CD1 4.44Å; L637-L648 PolarHBondContact O-N 3.36Å; V638-L648 HydrophobicContact CG1-CB 3.65Å; Q646-L648 WeakPolarHBondContact CB-O 3.49Å; L648-S667 CarbonylContact C-O 3.58Å; L648-S667 VanDerWaalsContact CA-O 3.32Å; L648-S667 WeakPolarHBondContact CA-O 3.25Å; L648-V668 HydrophobicContact CD2-CG2 4.08Å
649L96.2Very high90.6Very high78 Ų7875.9 Ų75.941%0.40838%0.383SS..EExtended strand (participates in β ladder)trans-106.7160.3166.6-57.2177.3000108.8F666 S667 N669L649-F666 WeakPolarHBondContact O-CA 3Å; L649-S667 PolarHBondContact N-O 3.2Å; L649-S667 PolarHBondContact O-N 2.77Å; L649-N669 HydrophobicContact CD1-CB 4.27Å; L649-N669 HydrophobicContact CD2-CB 4.15Å; L649-N669 HydrophobicContact CG-CB 3.82Å
650Y96.4Very high90.8Very high27 Ų2774.7 Ų74.711%0.10637%0.372CS..EExtended strand (participates in β ladder)trans-151.1156.3178.770.9-76.2000112.6V638 P652 Q653 V654 F660 T664 L665 F666V638-Y650 HydrophobicContact CB-CD1 3.59Å; V638-Y650 HydrophobicContact CB-CE1 3.89Å; V638-Y650 HydrophobicContact CG1-CD1 3.75Å; V638-Y650 HydrophobicContact CG1-CG 4.34Å; V638-Y650 HydrophobicContact CG2-CD1 3.84Å; V638-Y650 HydrophobicContact CG2-CE1 3.86Å; Y650-P652 WeakPolarHBondContact CD2-O 3.48Å; Y650-P652 WeakPolarHBondContact CE2-O 3.35Å; Y650-Q653 PolarHBondContact O-NE2 2.98Å; Y650-Q653 PolarHBondContact OH-OE1 3.44Å; Y650-Q653 VanDerWaalsContact OH-OE1 3.07Å; Y650-V654 HydrophobicContact CE2-CG2 3.92Å; Y650-V654 PolarHBondContact OH-N 3.4Å; Y650-V654 PolarHBondContact OH-O 3Å; Y650-F660 HydrophobicContact CD2-CD1 4.48Å; Y650-F660 AromaticContact CD2-CE1 3.69Å; Y650-F660 HydrophobicContact CD2-CE1 3.69Å; Y650-F660 AromaticContact CE2-CE1 3.78Å; Y650-F660 HydrophobicContact CE2-CE1 3.78Å; Y650-F660 HydrophobicContact CG-CE1 4.34Å; Y650-T664 HydrophobicContact CD2-CG2 4.35Å; Y650-L665 CarbonylContact C-O 3.59Å; Y650-L665 WeakPolarHBondContact CA-O 3.44Å; Y650-F666 HydrophobicContact CG-CE1 4.35Å
651E94.9Very high91.2Very high82 Ų8277.2 Ų77.238%0.38339%0.39SS..EExtended strand (participates in β ladder)trans-147.5140.7176.461.8-172.1-168.600110.9K613 L665K613-E651 VanDerWaalsContact CD-OE1 3.28Å; K613-E651 WeakPolarHBondContact CD-OE1 3.23Å; K613-E651 WeakPolarHBondContact CE-OE1 3.32Å; K613-E651 IonicContact NZ-OE1 3.64Å; K613-E651 PolarHBondContact NZ-OE1 2.91Å; K613-E651 IonicContact NZ-OE2 2.66Å; K613-E651 PolarHBondContact NZ-OE2 3.49Å; E651-L665 HydrophobicContact CG-CB 3.9Å; E651-L665 HydrophobicContact CG-CD1 4.46Å; E651-L665 PolarHBondContact N-O 2.74Å; E651-L665 PolarHBondContact O-N 2.93Å
652P94.7Very high91.8Very high83 Ų8374.5 Ų74.554%0.53937%0.366SS..SBendcis-70160.2-7.131.3-35.8000112.9Y650Y650-P652 WeakPolarHBondContact CD2-O 3.48Å; Y650-P652 WeakPolarHBondContact CE2-O 3.35Å
653Q93.3Very high92.5Very high139 Ų13968 Ų6865%0.6535%0.353SS*.  trans-69.5137.4177.3-69.6-66.7-57.800111.1Y650Y650-Q653 PolarHBondContact O-NE2 2.98Å; Y650-Q653 PolarHBondContact OH-OE1 3.44Å; Y650-Q653 VanDerWaalsContact OH-OE1 3.07Å
654V92.8Very high93Very high25 Ų2567 Ų6715%0.15235%0.348CS..  trans-140.8159.6-179.1-57.80000110.6W635 Y650 S656 D659 F660W635-V654 HydrophobicContact CZ3-CG2 4.18Å; Y650-V654 HydrophobicContact CE2-CG2 3.92Å; Y650-V654 PolarHBondContact OH-N 3.4Å; Y650-V654 PolarHBondContact OH-O 3Å; V654-S656 WeakPolarHBondContact CG2-O 3.5Å; V654-D659 HydrophobicContact CB-CB 3.69Å; V654-D659 HydrophobicContact CG1-CB 3.98Å; V654-D659 HydrophobicContact CG2-CB 4.01Å; V654-F660 HydrophobicContact CG2-CD1 3.48Å; V654-F660 VanDerWaalsContact CG2-CD1 3.48Å; V654-F660 HydrophobicContact CG2-CE1 3.47Å; V654-F660 VanDerWaalsContact CG2-CE1 3.47Å; V654-F660 HydrophobicContact CG2-CZ 4.48Å
655N88.9Confident93.5Very high157 Ų15761.9 Ų61.984%0.8433%0.328SS*.SBendtrans-95.7-12.2-173.2-65.5-38000113.7W635W635-N655 VanDerWaalsContact CH2-C 3.41Å; W635-N655 WeakPolarHBondContact CH2-O 3.45Å
656S88Confident93.7Very high33 Ų3357.6 Ų57.623%0.23131%0.312CS..SBendtrans-144.2155.7-179.7900000112.8V654 K658 D659V654-S656 WeakPolarHBondContact CG2-O 3.5Å; S656-K658 PolarHBondContact O-N 3.08Å; S656-K658 VanDerWaalsContact O-N 3.15Å; S656-K658 PolarHBondContact OG-N 3.23Å; S656-D659 VanDerWaalsContact CB-OD2 3.26Å; S656-D659 WeakPolarHBondContact CB-OD2 3.35Å; S656-D659 PolarHBondContact N-OD2 3.12Å; S656-D659 VanDerWaalsContact N-OD2 3.13Å; S656-D659 PolarHBondContact O-N 3.36Å; S656-D659 VanDerWaalsContact O-N 3.12Å; S656-D659 PolarHBondContact OG-OD1 3.41Å; S656-D659 PolarHBondContact OG-OD2 3.25Å
657P87Confident93.9Very high33 Ų3356.9 Ų56.921%0.21431%0.311CS..G310 helixtrans-59.6-24.5174.621.2-32.3000113.8R631 W635 D659 F660R631-P657 HydrophobicContact CB-CB 4.19Å; R631-P657 WeakPolarHBondContact CD-O 3.45Å; R631-P657 WeakPolarHBondContact CG-O 3.41Å; W635-P657 HydrophobicContact CB-CB 3.88Å; W635-P657 HydrophobicContact CB-CG 4.48Å; W635-P657 HydrophobicContact CD2-CB 4.21Å; W635-P657 HydrophobicContact CD2-CG 4.36Å; W635-P657 HydrophobicContact CE3-CB 4.3Å; W635-P657 HydrophobicContact CG-CB 4.03Å; W635-P657 HydrophobicContact CG-CG 4.2Å; P657-D659 VanDerWaalsContact C-N 3.26Å; P657-D659 PolarHBondContact O-N 3.49Å; P657-F660 WeakPolarHBondContact O-CD2 3.42Å
658K89Confident94Very high169 Ų16957.8 Ų57.874%0.73532%0.316SS*.G310 helixtrans-73.3-23.4-178.9-61.5-177.5-177.7178.20111.8S656 F660S656-K658 PolarHBondContact O-N 3.08Å; S656-K658 VanDerWaalsContact O-N 3.15Å; S656-K658 PolarHBondContact OG-N 3.23Å; K658-F660 VanDerWaalsContact C-N 3.34Å
659D92.9Very high94Very high81 Ų8158.4 Ų58.443%0.43332%0.319SS..G310 helixtrans-86.2-5.6-174.7-55.3-39.4000113V654 S656 P657 T661V654-D659 HydrophobicContact CB-CB 3.69Å; V654-D659 HydrophobicContact CG1-CB 3.98Å; V654-D659 HydrophobicContact CG2-CB 4.01Å; S656-D659 VanDerWaalsContact CB-OD2 3.26Å; S656-D659 WeakPolarHBondContact CB-OD2 3.35Å; S656-D659 PolarHBondContact N-OD2 3.12Å; S656-D659 VanDerWaalsContact N-OD2 3.13Å; S656-D659 PolarHBondContact O-N 3.36Å; S656-D659 VanDerWaalsContact O-N 3.12Å; S656-D659 PolarHBondContact OG-OD1 3.41Å; S656-D659 PolarHBondContact OG-OD2 3.25Å; P657-D659 VanDerWaalsContact C-N 3.26Å; P657-D659 PolarHBondContact O-N 3.49Å; D659-T661 PolarHBondContact O-N 3.28Å
660F93.4Very high94Very high6 Ų656.5 Ų56.53%0.02631%0.308CS..  trans-59.3141.1170.4-64.5-37.7000110.2F616 R631 L634 W635 V638 Y650 V654 P657 K658 T664 F666F616-F660 HydrophobicContact CD2-CB 4.37Å; R631-F660 HydrophobicContact CG-CD2 4.48Å; R631-F660 PolarHBondContact NH1-O 2.88Å; L634-F660 HydrophobicContact CB-CE2 4.17Å; W635-F660 HydrophobicContact CB-CE2 4.46Å; W635-F660 HydrophobicContact CE3-CE1 4.26Å; W635-F660 AromaticContact CE3-CE2 3.92Å; W635-F660 HydrophobicContact CE3-CE2 3.92Å; W635-F660 AromaticContact CE3-CZ 3.51Å; W635-F660 HydrophobicContact CE3-CZ 3.51Å; W635-F660 HydrophobicContact CZ3-CE1 4.29Å; W635-F660 AromaticContact CZ3-CZ 3.97Å; W635-F660 HydrophobicContact CZ3-CZ 3.97Å; V638-F660 HydrophobicContact CG2-CZ 4.03Å; Y650-F660 HydrophobicContact CD2-CD1 4.48Å; Y650-F660 AromaticContact CD2-CE1 3.69Å; Y650-F660 HydrophobicContact CD2-CE1 3.69Å; Y650-F660 AromaticContact CE2-CE1 3.78Å; Y650-F660 HydrophobicContact CE2-CE1 3.78Å; Y650-F660 HydrophobicContact CG-CE1 4.34Å; V654-F660 HydrophobicContact CG2-CD1 3.48Å; V654-F660 VanDerWaalsContact CG2-CD1 3.48Å; V654-F660 HydrophobicContact CG2-CE1 3.47Å; V654-F660 VanDerWaalsContact CG2-CE1 3.47Å; V654-F660 HydrophobicContact CG2-CZ 4.48Å; P657-F660 WeakPolarHBondContact O-CD2 3.42Å; K658-F660 VanDerWaalsContact C-N 3.34Å; F660-T664 HydrophobicContact CD1-CG2 3.85Å; F660-T664 HydrophobicContact CE1-CG2 4.38Å; F660-F666 HydrophobicContact CD1-CZ 4.02Å; F660-F666 HydrophobicContact CD2-CZ 4.08Å; F660-F666 HydrophobicContact CE1-CE1 4.1Å; F660-F666 AromaticContact CE1-CZ 3.96Å; F660-F666 HydrophobicContact CE1-CZ 3.96Å; F660-F666 HydrophobicContact CE2-CE1 4.22Å; F660-F666 HydrophobicContact CE2-CZ 4.03Å; F660-F666 HydrophobicContact CG-CZ 4.07Å; F660-F666 AromaticContact CZ-CE1 3.88Å; F660-F666 HydrophobicContact CZ-CE1 3.88Å; F660-F666 AromaticContact CZ-CZ 3.95Å; F660-F666 HydrophobicContact CZ-CZ 3.95Å
661T94.9Very high93.9Very high78 Ų7861.2 Ų61.248%0.47933%0.332SS..  trans-110.6163.3175.3650000108.8F616 D659 G663 T664F616-T661 VanDerWaalsContact CB-O 3.25Å; F616-T661 WeakPolarHBondContact CB-O 3.44Å; D659-T661 PolarHBondContact O-N 3.28Å; T661-G663 PolarHBondContact O-N 2.73Å; T661-G663 VanDerWaalsContact O-N 3.12Å; T661-T664 PolarHBondContact N-OG1 2.99Å; T661-T664 WeakPolarHBondContact O-CB 3.13Å; T661-T664 PolarHBondContact O-N 3.21Å; T661-T664 PolarHBondContact O-OG1 3.47Å; T661-T664 PolarHBondContact OG1-N 2.75Å; T661-T664 PolarHBondContact OG1-OG1 3.14Å
662E95Very high93.8Very high70 Ų7057.3 Ų57.333%0.32731%0.313SS..THydrogen-bonded Turntrans-55.2-30.8175.7-64.8-65.1161.800111.8F616 E617 K620F616-E662 WeakPolarHBondContact CD1-OE2 3.46Å; F616-E662 PolarHBondContact N-O 3.24Å; E617-E662 WeakPolarHBondContact CA-OE2 3.48Å; E617-E662 HydrophobicContact CB-CB 4.27Å; E617-E662 WeakPolarHBondContact CB-OE2 3.14Å; E617-E662 PolarHBondContact N-O 2.76Å; K620-E662 IonicContact NZ-OE1 3.79Å
663G95.4Very high93.8Very high52 Ų5253.5 Ų53.554%0.53629%0.289SS..THydrogen-bonded Turntrans-86.5-0.817600000116T661 L665T661-G663 PolarHBondContact O-N 2.73Å; T661-G663 VanDerWaalsContact O-N 3.12Å; G663-L665 PolarHBondContact O-N 2.79Å
664T96.6Very high93.6Very high1 Ų147.9 Ų47.91%0.00626%0.263CS..  trans-63.7124175.7-63.60000109.2S615 F616 Y650 F660 T661 F666S615-T664 CarbonylContact C-O 3.52Å; S615-T664 WeakPolarHBondContact CA-O 3.43Å; F616-T664 PolarHBondContact N-O 3.37Å; Y650-T664 HydrophobicContact CD2-CG2 4.35Å; F660-T664 HydrophobicContact CD1-CG2 3.85Å; F660-T664 HydrophobicContact CE1-CG2 4.38Å; T661-T664 PolarHBondContact N-OG1 2.99Å; T661-T664 WeakPolarHBondContact O-CB 3.13Å; T661-T664 PolarHBondContact O-N 3.21Å; T661-T664 PolarHBondContact O-OG1 3.47Å; T661-T664 PolarHBondContact OG1-N 2.75Å; T661-T664 PolarHBondContact OG1-OG1 3.14Å; T664-F666 HydrophobicContact CG2-CD2 4.44Å; T664-F666 HydrophobicContact CG2-CE1 4.44Å; T664-F666 HydrophobicContact CG2-CE2 3.68Å; T664-F666 HydrophobicContact CG2-CZ 3.67Å; T664-F666 WeakPolarHBondContact O-CD2 3.48Å; T664-F666 WeakPolarHBondContact O-CE2 3.41Å
665L97.5Very high93.5Very high58 Ų5849.1 Ų49.130%0.30427%0.268SS..EExtended strand (participates in β ladder)trans-95.3136.1-177-64.9176.1000110.2K613 Y650 E651 G663K613-L665 HydrophobicContact CB-CB 4.28Å; K613-L665 HydrophobicContact CB-CD1 4.46Å; K613-L665 HydrophobicContact CD-CD1 4.34Å; Y650-L665 CarbonylContact C-O 3.59Å; Y650-L665 WeakPolarHBondContact CA-O 3.44Å; E651-L665 HydrophobicContact CG-CB 3.9Å; E651-L665 HydrophobicContact CG-CD1 4.46Å; E651-L665 PolarHBondContact N-O 2.74Å; E651-L665 PolarHBondContact O-N 2.93Å; G663-L665 PolarHBondContact O-N 2.79Å
666F97.7Very high93.3Very high0 Ų048 Ų480%026%0.256CS..EExtended strand (participates in β ladder)trans-118.4146.3176.9-62.2-93000110.3W606 K613 I614 F616 L619 L634 V638 L649 Y650 F660 T664W606-F666 HydrophobicContact CH2-CB 3.98Å; W606-F666 HydrophobicContact CZ2-CB 3.85Å; W606-F666 WeakPolarHBondContact CZ2-O 3.44Å; K613-F666 CarbonylContact C-O 3.57Å; K613-F666 VanDerWaalsContact CA-O 3.3Å; K613-F666 WeakPolarHBondContact CA-O 3.44Å; I614-F666 PolarHBondContact N-O 3.29Å; I614-F666 PolarHBondContact O-N 3.17Å; F616-F666 HydrophobicContact CB-CE2 4.07Å; F616-F666 HydrophobicContact CD2-CE2 4.23Å; L619-F666 HydrophobicContact CD1-CB 4.05Å; L619-F666 HydrophobicContact CD1-CD2 3.76Å; L619-F666 HydrophobicContact CD1-CG 4.07Å; L634-F666 HydrophobicContact CB-CE1 4Å; L634-F666 HydrophobicContact CB-CZ 4.27Å; L634-F666 HydrophobicContact CD1-CD2 4.31Å; L634-F666 HydrophobicContact CD1-CE1 4.16Å; L634-F666 HydrophobicContact CD1-CE2 3.82Å; L634-F666 HydrophobicContact CD1-CZ 3.74Å; L634-F666 HydrophobicContact CD2-CD1 4.01Å; L634-F666 HydrophobicContact CD2-CE1 4.18Å; L634-F666 HydrophobicContact CD2-CG 4.22Å; L634-F666 HydrophobicContact CG-CE1 4.35Å; L634-F666 HydrophobicContact CG-CZ 4.41Å; V638-F666 HydrophobicContact CG1-CD1 4.02Å; V638-F666 HydrophobicContact CG1-CE1 4.16Å; L649-F666 WeakPolarHBondContact O-CA 3Å; Y650-F666 HydrophobicContact CG-CE1 4.35Å; F660-F666 HydrophobicContact CD1-CZ 4.02Å; F660-F666 HydrophobicContact CD2-CZ 4.08Å; F660-F666 HydrophobicContact CE1-CE1 4.1Å; F660-F666 AromaticContact CE1-CZ 3.96Å; F660-F666 HydrophobicContact CE1-CZ 3.96Å; F660-F666 HydrophobicContact CE2-CE1 4.22Å; F660-F666 HydrophobicContact CE2-CZ 4.03Å; F660-F666 HydrophobicContact CG-CZ 4.07Å; F660-F666 AromaticContact CZ-CE1 3.88Å; F660-F666 HydrophobicContact CZ-CE1 3.88Å; F660-F666 AromaticContact CZ-CZ 3.95Å; F660-F666 HydrophobicContact CZ-CZ 3.95Å; T664-F666 HydrophobicContact CG2-CD2 4.44Å; T664-F666 HydrophobicContact CG2-CE1 4.44Å; T664-F666 HydrophobicContact CG2-CE2 3.68Å; T664-F666 HydrophobicContact CG2-CZ 3.67Å; T664-F666 WeakPolarHBondContact O-CD2 3.48Å; T664-F666 WeakPolarHBondContact O-CE2 3.41Å
667S97.1Very high93.1Very high22 Ų2254.1 Ų54.115%0.15429%0.286CS..EExtended strand (participates in β ladder)trans-145.9155.8175580000112.5L648 L649 N669L648-S667 CarbonylContact C-O 3.58Å; L648-S667 VanDerWaalsContact CA-O 3.32Å; L648-S667 WeakPolarHBondContact CA-O 3.25Å; L649-S667 PolarHBondContact N-O 3.2Å; L649-S667 PolarHBondContact O-N 2.77Å; S667-N669 PolarHBondContact O-N 3.45Å
668V97.1Very high93Very high19 Ų1957 Ų5712%0.11531%0.312CS..EExtended strand (participates in β ladder)trans-68.4128.8174.1176.60000110F584 W606 L648 Q670F584-V668 HydrophobicContact CE2-CG1 3.67Å; F584-V668 HydrophobicContact CZ-CG1 3.53Å; W606-V668 HydrophobicContact CB-CG2 3.7Å; W606-V668 HydrophobicContact CD2-CG2 3.81Å; W606-V668 HydrophobicContact CE3-CG2 4.43Å; W606-V668 HydrophobicContact CG-CG2 3.46Å; W606-V668 VanDerWaalsContact CG-CG2 3.46Å; L648-V668 HydrophobicContact CD2-CG2 4.08Å; V668-Q670 PolarHBondContact O-N 3.35Å
669N96Very high93Very high13 Ų1356 Ų567%0.0731%0.308CS..  trans-73.697.9176.1-174-0.5000110.8N586 Q646 V647 L649 S667 E671 F672N586-N669 PolarHBondContact ND2-O 3.26Å; Q646-N669 WeakPolarHBondContact O-CB 3.45Å; Q646-N669 PolarHBondContact O-ND2 3.03Å; V647-N669 VanDerWaalsContact O-CB 3.29Å; V647-N669 WeakPolarHBondContact O-CB 3.12Å; V647-N669 PolarHBondContact O-N 3.15Å; L649-N669 HydrophobicContact CD1-CB 4.27Å; L649-N669 HydrophobicContact CD2-CB 4.15Å; L649-N669 HydrophobicContact CG-CB 3.82Å; S667-N669 PolarHBondContact O-N 3.45Å; N669-E671 PolarHBondContact O-N 2.77Å; N669-E671 PolarHBondContact OD1-N 3.27Å; N669-E671 VanDerWaalsContact OD1-N 3.08Å; N669-F672 HydrophobicContact CB-CB 3.98Å; N669-F672 WeakPolarHBondContact O-CB 3.49Å; N669-F672 PolarHBondContact O-N 2.94Å; N669-F672 PolarHBondContact OD1-N 2.83Å
670Q95.2Very high92.9Very high38 Ų3855.7 Ų55.718%0.17831%0.309CS..THydrogen-bonded Turntrans-65.6-20.5179.6-63.2-57.2-26.700113.3N586 E587 P610 V668N586-Q670 PolarHBondContact ND2-O 2.91Å; E587-Q670 HydrophobicContact CG-CB 4.1Å; E587-Q670 PolarHBondContact N-O 3.14Å; P610-Q670 PolarHBondContact O-NE2 2.94Å; V668-Q670 PolarHBondContact O-N 3.35Å
671E93.8Very high92.9Very high127 Ų12758.7 Ų58.759%0.59332%0.323SS*.THydrogen-bonded Turntrans-94.65.1175.5-58.5-170.2172.400113.7R645 N669 S673R645-E671 WeakPolarHBondContact CD-O 3.25Å; R645-E671 PolarHBondContact NH1-O 3.18Å; N669-E671 PolarHBondContact O-N 2.77Å; N669-E671 PolarHBondContact OD1-N 3.27Å; N669-E671 VanDerWaalsContact OD1-N 3.08Å; E671-S673 PolarHBondContact O-N 2.99Å
672F94.2Very high92.7Very high0 Ų062 Ų620%033%0.331CS..  trans-55.2131.5179.4170.9-98.6000111.2F584 N586 Y591 L643 R645 Q646 V647 N669 I686F584-F672 HydrophobicContact CD1-CD1 4.04Å; F584-F672 HydrophobicContact CD1-CE1 4.39Å; F584-F672 HydrophobicContact CE1-CB 4.23Å; F584-F672 AromaticContact CE1-CD1 3.65Å; F584-F672 HydrophobicContact CE1-CD1 3.65Å; F584-F672 HydrophobicContact CE1-CE1 4.38Å; F584-F672 HydrophobicContact CE1-CG 4.21Å; N586-F672 WeakPolarHBondContact ND2-CB 3.42Å; N586-F672 PolarHBondContact ND2-N 3.31Å; N586-F672 PolarHBondContact ND2-O 3.06Å; Y591-F672 HydrophobicContact CD1-CE1 4.3Å; Y591-F672 AromaticContact CD2-CD1 3.85Å; Y591-F672 HydrophobicContact CD2-CD1 3.85Å; Y591-F672 AromaticContact CD2-CE1 3.78Å; Y591-F672 HydrophobicContact CD2-CE1 3.78Å; Y591-F672 AromaticContact CE2-CD1 3.8Å; Y591-F672 HydrophobicContact CE2-CD1 3.8Å; Y591-F672 HydrophobicContact CE2-CE1 4.06Å; Y591-F672 HydrophobicContact CG-CD1 4.43Å; Y591-F672 AromaticContact CG-CE1 3.9Å; Y591-F672 HydrophobicContact CG-CE1 3.9Å; Y591-F672 PolarHBondContact OH-O 3.28Å; L643-F672 HydrophobicContact CD1-CE2 4.2Å; R645-F672 HydrophobicContact CB-CD2 4.3Å; R645-F672 VanDerWaalsContact O-CD2 3.28Å; R645-F672 WeakPolarHBondContact O-CD2 3.35Å; R645-F672 WeakPolarHBondContact O-CE2 3.29Å; Q646-F672 WeakPolarHBondContact O-CD2 3.49Å; V647-F672 HydrophobicContact CG2-CD2 4.39Å; V647-F672 HydrophobicContact CG2-CE2 3.94Å; V647-F672 HydrophobicContact CG2-CZ 4.14Å; N669-F672 HydrophobicContact CB-CB 3.98Å; N669-F672 WeakPolarHBondContact O-CB 3.49Å; N669-F672 PolarHBondContact O-N 2.94Å; N669-F672 PolarHBondContact OD1-N 2.83Å; F672-I686 HydrophobicContact CE1-CD1 3.87Å; F672-I686 HydrophobicContact CZ-CD1 3.4Å
673S93.2Very high92.7Very high3 Ų368 Ų682%0.02135%0.35CS..  trans-157.7152.2172.855.20000113.2Y591 E671Y591-S673 VanDerWaalsContact OH-CA 3.25Å; Y591-S673 WeakPolarHBondContact OH-CA 3.5Å; Y591-S673 VanDerWaalsContact OH-CB 3.24Å; Y591-S673 WeakPolarHBondContact OH-CB 3.49Å; E671-S673 PolarHBondContact O-N 2.99Å
674L90.5Very high92.5Very high20 Ų2066.7 Ų66.711%0.10534%0.337CS..EExtended strand (participates in β ladder)trans-76.6125.7171.9-76.8176.6000109.9Y591 L643 Q681 I686Y591-L674 HydrophobicContact CD1-CD1 3.97Å; Y591-L674 HydrophobicContact CD1-CG 4.07Å; Y591-L674 HydrophobicContact CE1-CB 4.25Å; Y591-L674 HydrophobicContact CE1-CD1 4.34Å; Y591-L674 HydrophobicContact CE1-CG 4.13Å; L643-L674 HydrophobicContact CD2-CD2 3.92Å; L674-Q681 HydrophobicContact CB-CB 3.99Å; L674-Q681 HydrophobicContact CB-CG 4.35Å; L674-Q681 WeakPolarHBondContact O-CB 3.34Å; L674-Q681 PolarHBondContact O-N 2.87Å; L674-I686 HydrophobicContact CD1-CD1 3.82Å; L674-I686 HydrophobicContact CD1-CG1 3.72Å; L674-I686 HydrophobicContact CD2-CD1 3.37Å; L674-I686 HydrophobicContact CD2-CG1 3.77Å; L674-I686 HydrophobicContact CG-CD1 3.58Å; L674-I686 HydrophobicContact CG-CG1 4.03Å
675I89.6Confident92.3Very high51 Ų5172.7 Ų72.726%0.26236%0.363SS..EExtended strand (participates in β ladder)trans-108108.2177.1-55.6178000108.1K644 R645K644-I675 HydrophobicContact CB-CD1 4.05Å; K644-I675 HydrophobicContact CD-CB 4.21Å; K644-I675 HydrophobicContact CD-CD1 4.06Å; K644-I675 HydrophobicContact CD-CG2 4.28Å; R645-I675 HydrophobicContact CG-CD1 4.4Å
676K84.6Confident91.9Very high133 Ų13370.5 Ų70.558%0.57835%0.352SS*.EExtended strand (participates in β ladder)trans-116.5128.3173.1-70.9-174.3178.2179.60108.8A678 K679 Q681K676-A678 VanDerWaalsContact C-N 3.28Å; K676-A678 PolarHBondContact O-N 3.37Å; K676-K679 PolarHBondContact N-O 3.06Å; K676-K679 PolarHBondContact O-N 3.07Å; K676-Q681 HydrophobicContact CB-CG 4.2Å; K676-Q681 HydrophobicContact CD-CG 4.46Å; K676-Q681 HydrophobicContact CG-CG 4.33Å
677N84.8Confident91.5Very high162 Ų16273.8 Ų73.887%0.86637%0.37SS*.THydrogen-bonded Turntrans49.846.8-179.1-57.8-16.2000113K679N677-K679 PolarHBondContact O-N 3.24Å
678A84.3Confident91.1Very high93 Ų9372.9 Ų72.977%0.76936%0.363SS*.THydrogen-bonded Turntrans59.67.9-175.500000116.2K676K676-A678 VanDerWaalsContact C-N 3.28Å; K676-A678 PolarHBondContact O-N 3.37Å
679K90Very high90.3Very high150 Ų15072.4 Ų72.465%0.65236%0.359SS*.EExtended strand (participates in β ladder)trans-105.8133.1176.4-65.1-177.1-178.5-178.40111.4K676 N677 Q681K676-K679 PolarHBondContact N-O 3.06Å; K676-K679 PolarHBondContact O-N 3.07Å; N677-K679 PolarHBondContact O-N 3.24Å; K679-Q681 PolarHBondContact O-N 3.41Å; K679-Q681 PolarHBondContact O-NE2 2.77Å
680V90.7Very high88.8Confident74 Ų7473.1 Ų73.145%0.44837%0.37SS..EExtended strand (participates in β ladder)trans-67.9124.5172.51730000109.3V588V588-V680 HydrophobicContact CG1-CG1 3.91Å
681Q92.1Very high86.7Confident68 Ų6881.5 Ų81.532%0.31840%0.4SS..EExtended strand (participates in β ladder)trans-98.4126.9173.8-52.9-61-52.900108.4Y591 L674 K676 K679 R683Y591-Q681 VanDerWaalsContact CE1-O 3.27Å; Y591-Q681 WeakPolarHBondContact CE1-O 3.47Å; Y591-Q681 PolarHBondContact OH-O 3.1Å; L674-Q681 HydrophobicContact CB-CB 3.99Å; L674-Q681 HydrophobicContact CB-CG 4.35Å; L674-Q681 WeakPolarHBondContact O-CB 3.34Å; L674-Q681 PolarHBondContact O-N 2.87Å; K676-Q681 HydrophobicContact CB-CG 4.2Å; K676-Q681 HydrophobicContact CD-CG 4.46Å; K676-Q681 HydrophobicContact CG-CG 4.33Å; K679-Q681 PolarHBondContact O-N 3.41Å; K679-Q681 PolarHBondContact O-NE2 2.77Å; Q681-R683 VanDerWaalsContact C-N 3.3Å
682K92.3Very high84.5Confident149 Ų14976 Ų7665%0.64838%0.375SS*.SBendtrans-82.3-8.5176.7-62.5-171.5176.5-173.90113.6G589 Q590G589-K682 CarbonylContact C-O 3.47Å; G589-K682 VanDerWaalsContact CA-O 3.23Å; G589-K682 WeakPolarHBondContact CA-O 3.16Å; Q590-K682 PolarHBondContact N-O 3.19Å
683R93.7Very high82.3Confident194 Ų19481.8 Ų81.873%0.73240%0.402SS*.EExtended strand (participates in β ladder)trans-143.2154.4177.5-64.8-174.5178.7178.1-1111.1Q590 Q681Q590-R683 VanDerWaalsContact O-CA 3.25Å; Q590-R683 WeakPolarHBondContact O-CA 3.34Å; Q681-R683 VanDerWaalsContact C-N 3.3Å
684G92Very high80.1Confident26 Ų2683.1 Ų83.127%0.26841%0.408SS..EExtended strand (participates in β ladder)trans161.2164.3170.800000113Y591 D592Y591-G684 CarbonylContact C-O 3.59Å; Y591-G684 WeakPolarHBondContact CA-O 3.34Å; D592-G684 PolarHBondContact N-O 2.8Å
685K91.4Very high78.3Confident126 Ų12684.5 Ų84.555%0.54842%0.418SS..EExtended strand (participates in β ladder)trans-98.8139.2175.5-172.5175.4-180179.60110.9D592D592-K685 HydrophobicContact CB-CB 4.35Å; D592-K685 HydrophobicContact CB-CG 4.23Å; D592-K685 CarbonylContact O-C 3.55Å; D592-K685 VanDerWaalsContact O-CA 3.28Å; D592-K685 WeakPolarHBondContact O-CA 3.46Å
686I90.5Very high76.8Confident13 Ų1382.4 Ų82.47%0.06741%0.408CS..EExtended strand (participates in β ladder)trans-134.4127.9-177.2-47.6179.8000108.8D592 L593 E594 L643 F672 L674 L688D592-I686 PolarHBondContact O-N 3.3Å; L593-I686 HydrophobicContact CD2-CB 3.93Å; L593-I686 HydrophobicContact CD2-CD1 3.73Å; L593-I686 HydrophobicContact CD2-CG1 4.07Å; E594-I686 PolarHBondContact N-O 3.25Å; L643-I686 HydrophobicContact CD1-CG2 4.4Å; L643-I686 HydrophobicContact CD2-CG2 4.33Å; F672-I686 HydrophobicContact CE1-CD1 3.87Å; F672-I686 HydrophobicContact CZ-CD1 3.4Å; L674-I686 HydrophobicContact CD1-CD1 3.82Å; L674-I686 HydrophobicContact CD1-CG1 3.72Å; L674-I686 HydrophobicContact CD2-CD1 3.37Å; L674-I686 HydrophobicContact CD2-CG1 3.77Å; L674-I686 HydrophobicContact CG-CD1 3.58Å; L674-I686 HydrophobicContact CG-CG1 4.03Å; I686-L688 HydrophobicContact CG2-CD2 3.75Å; I686-L688 HydrophobicContact CG2-CG 4.01Å
687N88.7Confident75.7Confident69 Ų6982 Ų8237%0.36941%0.408SS..EExtended strand (participates in β ladder)trans-93.3104.1171.3-174.9-51000109.7E594 F640 I689 G690E594-N687 PolarHBondContact OE1-ND2 3.37Å; E594-N687 PolarHBondContact OE2-ND2 3.4Å; F640-N687 WeakPolarHBondContact CZ-O 3.32Å; N687-I689 WeakPolarHBondContact OD1-CB 3.37Å; N687-I689 PolarHBondContact OD1-N 2.95Å; N687-G690 PolarHBondContact OD1-N 2.94Å
688L88.1Confident74.8Confident2 Ų280.1 Ų80.11%0.0139%0.388CS..  trans-97-8.7177.5-64.8179.3000112.9L593 E594 V595 Q599 L637 F640 L643 V647 I686 G690L593-L688 HydrophobicContact CB-CD1 4.07Å; L593-L688 HydrophobicContact CD1-CD1 3.88Å; L593-L688 HydrophobicContact CD2-CD1 4.11Å; L593-L688 HydrophobicContact CG-CD1 4.24Å; E594-L688 WeakPolarHBondContact O-CA 3.43Å; E594-L688 PolarHBondContact O-N 2.97Å; V595-L688 HydrophobicContact CG1-CB 4.05Å; V595-L688 HydrophobicContact CG1-CD1 3.99Å; Q599-L688 PolarHBondContact NE2-O 2.92Å; L637-L688 HydrophobicContact CD2-CD1 4.37Å; F640-L688 HydrophobicContact CD1-CD2 4.44Å; F640-L688 HydrophobicContact CD2-CD2 4.26Å; F640-L688 HydrophobicContact CE2-CD2 4.38Å; F640-L688 HydrophobicContact CG-CD2 4.28Å; L643-L688 HydrophobicContact CD1-CD2 3.65Å; V647-L688 HydrophobicContact CG2-CD1 3.79Å; V647-L688 HydrophobicContact CG2-CD2 4.45Å; I686-L688 HydrophobicContact CG2-CD2 3.75Å; I686-L688 HydrophobicContact CG2-CG 4.01Å; L688-G690 PolarHBondContact O-N 3Å; L688-G690 VanDerWaalsContact O-N 3.14Å
689I80.6Confident73.9Confident9 Ų977.7 Ų77.75%0.04636%0.362CS..SBendtrans-49.6-36.9164.7-62.3-179.2000109.1L464 N579 E594 T596 N687 R691 L692L464-I689 HydrophobicContact CD1-CG2 4.4Å; L464-I689 HydrophobicContact CD2-CD1 4.33Å; N579-I689 HydrophobicContact CB-CD1 3.57Å; N579-I689 HydrophobicContact CB-CG1 4.39Å; E594-I689 HydrophobicContact CG-CD1 3.67Å; E594-I689 HydrophobicContact CG-CG1 4.19Å; E594-I689 PolarHBondContact O-N 2.79Å; E594-I689 VanDerWaalsContact O-N 3.17Å; E594-I689 WeakPolarHBondContact OE1-CD1 3.47Å; T596-I689 HydrophobicContact CG2-CG1 4.39Å; T596-I689 HydrophobicContact CG2-CG2 4.26Å; N687-I689 WeakPolarHBondContact OD1-CB 3.37Å; N687-I689 PolarHBondContact OD1-N 2.95Å; I689-R691 CarbonylContact O-C 3.28Å; I689-L692 HydrophobicContact CG2-CB 3.58Å; I689-L692 HydrophobicContact CG2-CD1 3.3Å; I689-L692 HydrophobicContact CG2-CG 3.45Å; I689-L692 VanDerWaalsContact CG2-CG 3.45Å; I689-L692 WeakPolarHBondContact O-CA 3.44Å; I689-L692 PolarHBondContact O-N 3.47Å
690G64.1Low72.9Confident29 Ų2975 Ų7530%0.29935%0.348SS..  trans65.2-151.5176.400000111.5R460 N687 L688 L692R460-G690 PolarHBondContact NH2-O 3.41Å; N687-G690 PolarHBondContact OD1-N 2.94Å; L688-G690 PolarHBondContact O-N 3Å; L688-G690 VanDerWaalsContact O-N 3.14Å; G690-L692 PolarHBondContact O-N 3.35Å
691R52Low72Confident213 Ų21374.8 Ų74.880%0.80434%0.341SS*.SBendtrans-72.977.9149.9-70-173.5-166.7179.33.8105.5R460 I689 Q693R460-R691 VanDerWaalsContact NH2-CA 3.27Å; I689-R691 CarbonylContact O-C 3.28Å; R691-Q693 PolarHBondContact O-N 3.18Å
692L46.9Very low71.1Confident11 Ų1174.5 Ų74.56%0.05834%0.34CS..  trans-22.9107.9161.1-140.7164.9000105.6R460 L464 T596 I689 G690 L694R460-L692 PolarHBondContact NH1-O 2.74Å; R460-L692 PolarHBondContact NH2-O 2.87Å; L464-L692 HydrophobicContact CD1-CD1 3.9Å; L464-L692 HydrophobicContact CD2-CD1 3.82Å; L464-L692 HydrophobicContact CG-CD1 4.39Å; T596-L692 HydrophobicContact CG2-CD1 4.21Å; T596-L692 HydrophobicContact CG2-CD2 4.05Å; T596-L692 HydrophobicContact CG2-CG 3.75Å; I689-L692 HydrophobicContact CG2-CB 3.58Å; I689-L692 HydrophobicContact CG2-CD1 3.3Å; I689-L692 HydrophobicContact CG2-CG 3.45Å; I689-L692 VanDerWaalsContact CG2-CG 3.45Å; I689-L692 WeakPolarHBondContact O-CA 3.44Å; I689-L692 PolarHBondContact O-N 3.47Å; G690-L692 PolarHBondContact O-N 3.35Å; L692-L694 HydrophobicContact CB-CG 4.19Å; L692-L694 HydrophobicContact CD2-CD2 3.68Å; L692-L694 HydrophobicContact CD2-CG 3.73Å; L692-L694 HydrophobicContact CG-CG 4.38Å; L692-L694 PolarHBondContact O-N 2.83Å
693Q47.9Very low70.1Confident123 Ų12368.1 Ų68.158%0.57531%0.313SS*.  trans-74.266.1-176.8-75.4-171.6-7.300107.1R691 T695 T696R691-Q693 PolarHBondContact O-N 3.18Å; Q693-T695 PolarHBondContact O-N 3.36Å; Q693-T695 VanDerWaalsContact O-N 3.1Å; Q693-T696 HydrophobicContact CB-CG2 4.5Å
694L47.7Very low69.4Low30 Ų3059.7 Ų59.716%0.15728%0.282CS..SBendtrans-60.7-10.5166.5-70169.8000110.5R460 L692 M699R460-L694 HydrophobicContact CB-CD1 3.53Å; R460-L694 HydrophobicContact CG-CD1 3.5Å; R460-L694 VanDerWaalsContact CG-CD1 3.5Å; L692-L694 HydrophobicContact CB-CG 4.19Å; L692-L694 HydrophobicContact CD2-CD2 3.68Å; L692-L694 HydrophobicContact CD2-CG 3.73Å; L692-L694 HydrophobicContact CG-CG 4.38Å; L692-L694 PolarHBondContact O-N 2.83Å; L694-M699 WeakPolarHBondContact O-CE 3.39Å
695T53Low68.9Low50 Ų5060.7 Ų60.731%0.30728%0.28SS..SBendtrans-13082.8171.743.60000109.4Q693 R700 E703Q693-T695 PolarHBondContact O-N 3.36Å; Q693-T695 VanDerWaalsContact O-N 3.1Å; T695-R700 HydrophobicContact CG2-CG 4.46Å; T695-R700 PolarHBondContact O-NH1 2.96Å; T695-E703 WeakPolarHBondContact CG2-OE2 3.48Å
696T57.6Low68.4Low7 Ų755.8 Ų55.84%0.04327%0.265CS..  trans-63.6160161.170.90000109Q693 R698 M699 R700Q693-T696 HydrophobicContact CB-CG2 4.5Å; T696-R698 PolarHBondContact O-N 3.38Å; T696-M699 HydrophobicContact CG2-SD 4.23Å; T696-M699 PolarHBondContact O-N 3.5Å; T696-M699 WeakPolarHBondContact OG1-CG 3.3Å; T696-M699 PolarHBondContact OG1-N 2.9Å; T696-R700 PolarHBondContact O-N 2.64Å
697E62.1Low68.2Low123 Ų12355.4 Ų55.458%0.57526%0.263SS*.Hα-helixtrans-53.8-39.4175.1-172.5142.7-118.400111.9R700 E701E697-R700 PolarHBondContact O-N 3.13Å; E697-R700 IonicContact OE1-NH2 3.02Å; E697-R700 PolarHBondContact OE1-NH2 3.47Å; E697-E701 PolarHBondContact O-N 3.33Å
698R66.1Low68.1Low123 Ų12352.7 Ų52.746%0.46425%0.249SC..Hα-helixtrans-60.8-45.8171.7-177.1178171.9-169.8-3.4112.9E541 T696 R700 E701 E702E541-R698 IonicContact OE1-NH2 3.43Å; E541-R698 IonicContact OE2-CZ 3.9Å; E541-R698 VanDerWaalsContact OE2-CZ 3.24Å; E541-R698 IonicContact OE2-NH1 2.66Å; E541-R698 PolarHBondContact OE2-NH1 3.15Å; E541-R698 IonicContact OE2-NH2 3.72Å; E541-R698 PolarHBondContact OE2-NH2 3.32Å; T696-R698 PolarHBondContact O-N 3.38Å; R698-R700 VanDerWaalsContact C-N 3.31Å; R698-R700 PolarHBondContact O-N 2.96Å; R698-E701 WeakPolarHBondContact O-CB 3.46Å; R698-E701 PolarHBondContact O-N 2.66Å; R698-E702 WeakPolarHBondContact CG-OE1 3.45Å; R698-E702 IonicContact CZ-OE1 3.49Å; R698-E702 IonicContact NE-OE1 3.47Å; R698-E702 PolarHBondContact NE-OE1 3.49Å; R698-E702 IonicContact NH2-OE1 3.77Å; R698-E702 PolarHBondContact NH2-OE1 3.12Å; R698-E702 WeakPolarHBondContact O-CG 3.45Å; R698-E702 PolarHBondContact O-N 3.46Å
699M64.9Low68.1Low42 Ų4258.2 Ų58.221%0.20728%0.275CS..Hα-helixtrans-65.8-33.8177.2-72.8176.986.300112.1L576 L694 T696 E702 E703L576-M699 HydrophobicContact CD2-CE 4.34Å; L694-M699 WeakPolarHBondContact O-CE 3.39Å; T696-M699 HydrophobicContact CG2-SD 4.23Å; T696-M699 PolarHBondContact O-N 3.5Å; T696-M699 WeakPolarHBondContact OG1-CG 3.3Å; T696-M699 PolarHBondContact OG1-N 2.9Å; M699-E702 PolarHBondContact O-N 3.31Å; M699-E703 VanDerWaalsContact O-CB 3.27Å; M699-E703 WeakPolarHBondContact O-CB 3.44Å; M699-E703 WeakPolarHBondContact O-CG 3.26Å; M699-E703 PolarHBondContact O-N 3.1Å
700R68.2Low68.4Low95 Ų9560.6 Ų60.636%0.35829%0.287SS..Hα-helixtrans-64.3-42.5172.1-67.3-169.7-61.8-93.46.2111.6T695 T696 E697 R698 E703 N704T695-R700 HydrophobicContact CG2-CG 4.46Å; T695-R700 PolarHBondContact O-NH1 2.96Å; T696-R700 PolarHBondContact O-N 2.64Å; E697-R700 PolarHBondContact O-N 3.13Å; E697-R700 IonicContact OE1-NH2 3.02Å; E697-R700 PolarHBondContact OE1-NH2 3.47Å; R698-R700 VanDerWaalsContact C-N 3.31Å; R698-R700 PolarHBondContact O-N 2.96Å; R700-E703 PolarHBondContact O-N 3.45Å; R700-N704 WeakPolarHBondContact O-CB 3.45Å; R700-N704 PolarHBondContact O-N 2.96Å; R700-N704 PolarHBondContact O-OD1 3.38Å
701E71.6Confident69.8Low68 Ų6859.8 Ų59.832%0.31828%0.275SS..Hα-helixtrans-60.9-47.7173.6-72.2-179.8-163.100111.3K390 E697 R698 E703 N704 E705K390-E701 IonicContact NZ-OE2 3.39Å; K390-E701 PolarHBondContact NZ-OE2 3.47Å; E697-E701 PolarHBondContact O-N 3.33Å; R698-E701 WeakPolarHBondContact O-CB 3.46Å; R698-E701 PolarHBondContact O-N 2.66Å; E701-E703 VanDerWaalsContact C-N 3.32Å; E701-E703 PolarHBondContact O-N 3.24Å; E701-N704 PolarHBondContact O-N 3.38Å; E701-E705 WeakPolarHBondContact O-CB 3.09Å; E701-E705 WeakPolarHBondContact O-CG 3.45Å; E701-E705 PolarHBondContact O-N 2.96Å
702E72.7Confident71.7Confident62 Ų6251.1 Ų51.129%0.2924%0.244SC..Hα-helixtrans-63.7-35.8177.6-70.9170.1-17700112.2R698 M699 G706R698-E702 WeakPolarHBondContact CG-OE1 3.45Å; R698-E702 IonicContact CZ-OE1 3.49Å; R698-E702 IonicContact NE-OE1 3.47Å; R698-E702 PolarHBondContact NE-OE1 3.49Å; R698-E702 IonicContact NH2-OE1 3.77Å; R698-E702 PolarHBondContact NH2-OE1 3.12Å; R698-E702 WeakPolarHBondContact O-CG 3.45Å; R698-E702 PolarHBondContact O-N 3.46Å; M699-E702 PolarHBondContact O-N 3.31Å; E702-G706 PolarHBondContact O-N 3.07Å
703E73Confident73.9Confident16 Ų1655.4 Ų55.48%0.07527%0.267CS..Hα-helixtrans-63.6-45.8172.2-78.9173.1164.800111.4T695 M699 R700 E701 G706 I707T695-E703 WeakPolarHBondContact CG2-OE2 3.48Å; M699-E703 VanDerWaalsContact O-CB 3.27Å; M699-E703 WeakPolarHBondContact O-CB 3.44Å; M699-E703 WeakPolarHBondContact O-CG 3.26Å; M699-E703 PolarHBondContact O-N 3.1Å; R700-E703 PolarHBondContact O-N 3.45Å; E701-E703 VanDerWaalsContact C-N 3.32Å; E701-E703 PolarHBondContact O-N 3.24Å; E703-G706 PolarHBondContact O-N 3.37Å; E703-I707 WeakPolarHBondContact O-CG1 3.47Å; E703-I707 PolarHBondContact O-N 3.36Å
704N79Confident76.1Confident16 Ų1652 Ų529%0.08625%0.248CC..Hα-helixtrans-64.3-45.7177.5-72.1-8.4000111.5L387 R700 E701 G706 I707 V708L387-N704 HydrophobicContact CD2-CB 3.64Å; L387-N704 VanDerWaalsContact CD2-CG 3.49Å; L387-N704 WeakPolarHBondContact CD2-OD1 3.41Å; R700-N704 WeakPolarHBondContact O-CB 3.45Å; R700-N704 PolarHBondContact O-N 2.96Å; R700-N704 PolarHBondContact O-OD1 3.38Å; E701-N704 PolarHBondContact O-N 3.38Å; N704-G706 VanDerWaalsContact C-N 3.28Å; N704-G706 PolarHBondContact O-N 2.77Å; N704-I707 WeakPolarHBondContact O-CB 3.25Å; N704-I707 PolarHBondContact O-N 3.34Å; N704-V708 WeakPolarHBondContact O-CG2 3.43Å; N704-V708 PolarHBondContact O-N 3.33Å; N704-V708 VanDerWaalsContact O-N 3.12Å
705E80.3Confident78.3Confident48 Ų4850.6 Ų50.622%0.22424%0.241CC..Hα-helixtrans-59.7-41.1174-74179.8-17700111.1E701 I707 V708 Q709E701-E705 WeakPolarHBondContact O-CB 3.09Å; E701-E705 WeakPolarHBondContact O-CG 3.45Å; E701-E705 PolarHBondContact O-N 2.96Å; E705-I707 VanDerWaalsContact C-N 3.35Å; E705-I707 PolarHBondContact O-N 3.34Å; E705-V708 PolarHBondContact O-N 3.29Å; E705-Q709 WeakPolarHBondContact O-CB 3.47Å; E705-Q709 WeakPolarHBondContact O-CG 3.39Å; E705-Q709 PolarHBondContact O-N 2.88Å
706G82.4Confident80.3Confident22 Ų2249.3 Ų49.323%0.22723%0.232CC..Hα-helixtrans-61.8-38175.500000113.4E702 E703 N704 L710E702-G706 PolarHBondContact O-N 3.07Å; E703-G706 PolarHBondContact O-N 3.37Å; N704-G706 VanDerWaalsContact C-N 3.28Å; N704-G706 PolarHBondContact O-N 2.77Å; G706-L710 WeakPolarHBondContact O-CB 3.29Å; G706-L710 PolarHBondContact O-N 3.39Å
707I85.3Confident82.1Confident6 Ų653.7 Ų53.73%0.03125%0.252CS..Hα-helixtrans-61.6-50.3172.9-67.7164.7000109.5L387 V449 R452 E703 N704 E705 Q709 L710 R711L387-I707 HydrophobicContact CD1-CG2 4.25Å; L387-I707 HydrophobicContact CD2-CD1 4.34Å; V449-I707 HydrophobicContact CG2-CD1 4.37Å; V449-I707 HydrophobicContact CG2-CG2 4.4Å; R452-I707 HydrophobicContact CB-CD1 4.11Å; R452-I707 HydrophobicContact CB-CG1 4.15Å; R452-I707 HydrophobicContact CG-CD1 4.04Å; R452-I707 HydrophobicContact CG-CG1 4.01Å; E703-I707 WeakPolarHBondContact O-CG1 3.47Å; E703-I707 PolarHBondContact O-N 3.36Å; N704-I707 WeakPolarHBondContact O-CB 3.25Å; N704-I707 PolarHBondContact O-N 3.34Å; E705-I707 VanDerWaalsContact C-N 3.35Å; E705-I707 PolarHBondContact O-N 3.34Å; I707-Q709 PolarHBondContact O-N 3.15Å; I707-L710 PolarHBondContact O-N 2.91Å; I707-R711 WeakPolarHBondContact O-CG 3.4Å; I707-R711 PolarHBondContact O-N 3.04Å
708V86.8Confident83.7Confident11 Ų1148 Ų487%0.06723%0.226CC..Hα-helixtrans-65.3-42.5-176.9-1750000111.8L387 L389 N704 E705 L710 R711 I712L387-V708 HydrophobicContact CB-CG2 3.84Å; L387-V708 HydrophobicContact CD1-CG2 4.31Å; L389-V708 HydrophobicContact CD1-CG1 4.11Å; L389-V708 HydrophobicContact CD2-CB 4.15Å; L389-V708 HydrophobicContact CD2-CG1 3.38Å; L389-V708 HydrophobicContact CG-CG1 3.81Å; N704-V708 WeakPolarHBondContact O-CG2 3.43Å; N704-V708 PolarHBondContact O-N 3.33Å; N704-V708 VanDerWaalsContact O-N 3.12Å; E705-V708 PolarHBondContact O-N 3.29Å; V708-L710 VanDerWaalsContact C-N 3.31Å; V708-L710 PolarHBondContact O-N 3.2Å; V708-R711 WeakPolarHBondContact O-CB 3.48Å; V708-R711 PolarHBondContact O-N 3.38Å; V708-I712 HydrophobicContact CG1-CD1 4.32Å; V708-I712 WeakPolarHBondContact O-CG1 3.29Å; V708-I712 PolarHBondContact O-N 2.89Å
709Q87.5Confident85.1Confident119 Ų11942.2 Ų42.256%0.55620%0.204SC*.Hα-helixtrans-59.7-41.8174.4-73.2179.210.700111.8E705 I707 I712 L713E705-Q709 WeakPolarHBondContact O-CB 3.47Å; E705-Q709 WeakPolarHBondContact O-CG 3.39Å; E705-Q709 PolarHBondContact O-N 2.88Å; I707-Q709 PolarHBondContact O-N 3.15Å; Q709-I712 WeakPolarHBondContact O-CB 3.43Å; Q709-I712 PolarHBondContact O-N 3.05Å; Q709-L713 WeakPolarHBondContact O-CG 3.5Å; Q709-L713 PolarHBondContact O-N 3.29Å; Q709-L713 VanDerWaalsContact O-N 3.09Å
710L88.4Confident86.6Confident59 Ų5942.3 Ų42.331%0.30921%0.205SC..Hα-helixtrans-65.9-39.9177.3-173.860.1000111.6Y489 G706 I707 V708 I712 L713 R714Y489-L710 HydrophobicContact CE1-CD2 4.16Å; Y489-L710 WeakPolarHBondContact OH-CD2 3.35Å; G706-L710 WeakPolarHBondContact O-CB 3.29Å; G706-L710 PolarHBondContact O-N 3.39Å; I707-L710 PolarHBondContact O-N 2.91Å; V708-L710 VanDerWaalsContact C-N 3.31Å; V708-L710 PolarHBondContact O-N 3.2Å; L710-I712 VanDerWaalsContact C-N 3.32Å; L710-I712 PolarHBondContact O-N 2.91Å; L710-L713 PolarHBondContact O-N 3.19Å; L710-R714 HydrophobicContact CD1-CG 4.21Å; L710-R714 HydrophobicContact CG-CG 4.27Å; L710-R714 WeakPolarHBondContact O-CB 3.32Å; L710-R714 WeakPolarHBondContact O-CG 3.46Å; L710-R714 PolarHBondContact O-N 3.17Å
711R92Very high87.9Confident12 Ų1243.5 Ų43.55%0.04522%0.215CC..Hα-helixtrans-60.5-40.7174.4-71.2-179.9177.8177.20.3112.3E401 D448 I707 V708 T715 F746 M752E401-R711 IonicContact OE1-CZ 2.79Å; E401-R711 IonicContact OE1-NH1 3.23Å; E401-R711 PolarHBondContact OE1-NH1 3.38Å; E401-R711 IonicContact OE1-NH2 2.79Å; E401-R711 IonicContact OE2-CZ 2.99Å; E401-R711 IonicContact OE2-NH1 3.88Å; E401-R711 PolarHBondContact OE2-NH1 2.92Å; E401-R711 IonicContact OE2-NH2 2.75Å; E401-R711 PolarHBondContact OE2-NH2 3.43Å; D448-R711 IonicContact OD1-CZ 3.33Å; D448-R711 IonicContact OD1-NE 2.68Å; D448-R711 IonicContact OD1-NH2 3.82Å; D448-R711 PolarHBondContact OD1-NH2 3.24Å; D448-R711 WeakPolarHBondContact OD2-CG 3.31Å; D448-R711 IonicContact OD2-CZ 3.25Å; D448-R711 IonicContact OD2-NE 2.79Å; D448-R711 PolarHBondContact OD2-NE 3.43Å; D448-R711 IonicContact OD2-NH2 3.9Å; D448-R711 PolarHBondContact OD2-NH2 3.37Å; I707-R711 WeakPolarHBondContact O-CG 3.4Å; I707-R711 PolarHBondContact O-N 3.04Å; V708-R711 WeakPolarHBondContact O-CB 3.48Å; V708-R711 PolarHBondContact O-N 3.38Å; R711-T715 WeakPolarHBondContact O-CB 3.49Å; R711-T715 PolarHBondContact O-N 2.96Å; R711-T715 PolarHBondContact O-OG1 2.94Å; R711-F746 HydrophobicContact CB-CD2 4.45Å; R711-F746 HydrophobicContact CB-CE1 4.12Å; R711-F746 HydrophobicContact CB-CE2 4.02Å; R711-F746 HydrophobicContact CB-CZ 3.83Å; R711-F746 HydrophobicContact CG-CD1 3.79Å; R711-F746 HydrophobicContact CG-CD2 3.97Å; R711-F746 HydrophobicContact CG-CE1 3.83Å; R711-F746 HydrophobicContact CG-CE2 4.02Å; R711-F746 HydrophobicContact CG-CG 3.87Å; R711-F746 HydrophobicContact CG-CZ 3.94Å; R711-M752 HydrophobicContact CB-CE 4.12Å; R711-M752 HydrophobicContact CB-SD 4.08Å
712I93Very high89.1Confident31 Ų3140.6 Ų40.616%0.15920%0.201CC..Hα-helixtrans-57.8-54.9174.2-73.1168000110.1V708 Q709 L710 R714 T715 Q716 M752V708-I712 HydrophobicContact CG1-CD1 4.32Å; V708-I712 WeakPolarHBondContact O-CG1 3.29Å; V708-I712 PolarHBondContact O-N 2.89Å; Q709-I712 WeakPolarHBondContact O-CB 3.43Å; Q709-I712 PolarHBondContact O-N 3.05Å; L710-I712 VanDerWaalsContact C-N 3.32Å; L710-I712 PolarHBondContact O-N 2.91Å; I712-R714 PolarHBondContact O-N 3.16Å; I712-T715 WeakPolarHBondContact O-CB 3.3Å; I712-T715 PolarHBondContact O-N 3.14Å; I712-Q716 WeakPolarHBondContact O-CG 3.41Å; I712-Q716 PolarHBondContact O-N 3.39Å; I712-M752 HydrophobicContact CG1-SD 4.27Å
713L92.8Very high90.2Very high101 Ų10137.6 Ų37.653%0.52919%0.187SC..Hα-helixtrans-61.2-42.5-178.5-66.6172.8000112.4Q709 L710 T715 Q716 E717Q709-L713 WeakPolarHBondContact O-CG 3.5Å; Q709-L713 PolarHBondContact O-N 3.29Å; Q709-L713 VanDerWaalsContact O-N 3.09Å; L710-L713 PolarHBondContact O-N 3.19Å; L713-T715 VanDerWaalsContact C-N 3.33Å; L713-T715 PolarHBondContact O-N 3.25Å; L713-Q716 PolarHBondContact O-N 3.47Å; L713-E717 WeakPolarHBondContact O-CB 3.49Å; L713-E717 PolarHBondContact O-N 3.5Å
714R93.4Very high91.2Very high51 Ų5143 Ų4319%0.19221%0.21CC..Hα-helixtrans-65.9-35.9177.4-70-66.2-170.9-166.57.2112.5D488 L710 I712 E717 A718 L742 M745 F746D488-R714 IonicContact OD2-CZ 3.84Å; D488-R714 IonicContact OD2-NH2 3.45Å; D488-R714 PolarHBondContact OD2-NH2 3.33Å; L710-R714 HydrophobicContact CD1-CG 4.21Å; L710-R714 HydrophobicContact CG-CG 4.27Å; L710-R714 WeakPolarHBondContact O-CB 3.32Å; L710-R714 WeakPolarHBondContact O-CG 3.46Å; L710-R714 PolarHBondContact O-N 3.17Å; I712-R714 PolarHBondContact O-N 3.16Å; R714-E717 WeakPolarHBondContact CD-OE2 3.46Å; R714-E717 IonicContact CZ-OE2 2.71Å; R714-E717 IonicContact NE-OE2 2.7Å; R714-E717 IonicContact NH1-OE1 3.22Å; R714-E717 IonicContact NH1-OE2 3.19Å; R714-E717 PolarHBondContact NH1-OE2 3.02Å; R714-A718 VanDerWaalsContact O-CB 3.3Å; R714-A718 WeakPolarHBondContact O-CB 3.46Å; R714-A718 PolarHBondContact O-N 2.72Å; R714-L742 HydrophobicContact CB-CD2 4.37Å; R714-M745 HydrophobicContact CB-CE 4.4Å; R714-M745 HydrophobicContact CG-CE 3.73Å; R714-F746 HydrophobicContact CB-CE1 4.06Å; R714-F746 HydrophobicContact CB-CZ 4.39Å
715T95Very high92Very high0 Ų049.2 Ų49.20%024%0.24CC..Hα-helixtrans-65.2-45.6174.3-57.30000110.8R711 I712 L713 A718 I719 L738 M752 Q756R711-T715 WeakPolarHBondContact O-CB 3.49Å; R711-T715 PolarHBondContact O-N 2.96Å; R711-T715 PolarHBondContact O-OG1 2.94Å; I712-T715 WeakPolarHBondContact O-CB 3.3Å; I712-T715 PolarHBondContact O-N 3.14Å; L713-T715 VanDerWaalsContact C-N 3.33Å; L713-T715 PolarHBondContact O-N 3.25Å; T715-A718 PolarHBondContact O-N 2.97Å; T715-I719 HydrophobicContact CG2-CD1 3.92Å; T715-I719 VanDerWaalsContact O-CG1 3.25Å; T715-I719 WeakPolarHBondContact O-CG1 3.33Å; T715-I719 PolarHBondContact O-N 2.93Å; T715-L738 HydrophobicContact CG2-CD2 4.22Å; T715-M752 VanDerWaalsContact OG1-CE 3.24Å; T715-M752 WeakPolarHBondContact OG1-CE 3.41Å; T715-Q756 HydrophobicContact CG2-CB 4.01Å; T715-Q756 HydrophobicContact CG2-CG 3.83Å
716Q95Very high92.7Very high23 Ų2352.9 Ų52.911%0.10725%0.252CS..Hα-helixtrans-60.8-48.6176.2-67.6170.7-6.300111.7I712 L713 A718 I719 I720 Q756 W759I712-Q716 WeakPolarHBondContact O-CG 3.41Å; I712-Q716 PolarHBondContact O-N 3.39Å; L713-Q716 PolarHBondContact O-N 3.47Å; Q716-A718 PolarHBondContact O-N 3.42Å; Q716-I719 PolarHBondContact O-N 3.21Å; Q716-I720 WeakPolarHBondContact O-CG1 3.48Å; Q716-I720 PolarHBondContact O-N 2.86Å; Q716-Q756 HydrophobicContact CG-CB 4.27Å; Q716-Q756 HydrophobicContact CG-CG 4.23Å; Q716-W759 HydrophobicContact CG-CE3 4.26Å; Q716-W759 HydrophobicContact CG-CZ3 4.44Å
717E94.5Very high93.3Very high100 Ų10056.9 Ų56.947%0.46726%0.263SS..Hα-helixtrans-56.6-49.5177.6-178.6-175.3-169.100111.8L713 R714 I719 I720 Q721L713-E717 WeakPolarHBondContact O-CB 3.49Å; L713-E717 PolarHBondContact O-N 3.5Å; R714-E717 WeakPolarHBondContact CD-OE2 3.46Å; R714-E717 IonicContact CZ-OE2 2.71Å; R714-E717 IonicContact NE-OE2 2.7Å; R714-E717 IonicContact NH1-OE1 3.22Å; R714-E717 IonicContact NH1-OE2 3.19Å; R714-E717 PolarHBondContact NH1-OE2 3.02Å; E717-I719 PolarHBondContact O-N 2.62Å; E717-I720 PolarHBondContact O-N 3.23Å; E717-Q721 WeakPolarHBondContact O-CB 3.47Å; E717-Q721 PolarHBondContact O-N 3.26Å
718A95.5Very high93.8Very high4 Ų462.1 Ų62.13%0.03329%0.286CS..Hα-helixtrans-63.9-41.7-179.800000112.3R714 T715 Q716 Q721 I722 L738 I741 L742R714-A718 VanDerWaalsContact O-CB 3.3Å; R714-A718 WeakPolarHBondContact O-CB 3.46Å; R714-A718 PolarHBondContact O-N 2.72Å; T715-A718 PolarHBondContact O-N 2.97Å; Q716-A718 PolarHBondContact O-N 3.42Å; A718-Q721 PolarHBondContact O-N 3.42Å; A718-I722 WeakPolarHBondContact O-CG1 3.31Å; A718-I722 PolarHBondContact O-N 3.25Å; A718-L738 HydrophobicContact CB-CD1 3.51Å; A718-I741 HydrophobicContact CB-CG2 4.11Å; A718-L742 HydrophobicContact CB-CD1 4.42Å; A718-L742 HydrophobicContact CB-CD2 4.1Å; A718-L742 HydrophobicContact CB-CG 4.25Å
719I96.4Very high94.3Very high0 Ų061.9 Ų61.90%028%0.284CS..Hα-helixtrans-61.2-47.2174.7-67.1165.2000110.2T715 Q716 E717 Q721 I722 M723 L734 L738 Q756 I757 L760T715-I719 HydrophobicContact CG2-CD1 3.92Å; T715-I719 VanDerWaalsContact O-CG1 3.25Å; T715-I719 WeakPolarHBondContact O-CG1 3.33Å; T715-I719 PolarHBondContact O-N 2.93Å; Q716-I719 PolarHBondContact O-N 3.21Å; E717-I719 PolarHBondContact O-N 2.62Å; I719-Q721 VanDerWaalsContact C-N 3.31Å; I719-Q721 PolarHBondContact O-N 3.2Å; I719-I722 PolarHBondContact O-N 3.48Å; I719-M723 HydrophobicContact CG2-CG 3.99Å; I719-M723 VanDerWaalsContact O-CB 3.3Å; I719-M723 WeakPolarHBondContact O-CB 3.49Å; I719-M723 WeakPolarHBondContact O-CG 3.25Å; I719-M723 PolarHBondContact O-N 2.91Å; I719-L734 HydrophobicContact CG2-CD1 4.35Å; I719-L734 HydrophobicContact CG2-CD2 4.35Å; I719-L738 HydrophobicContact CD1-CD2 4.18Å; I719-L738 HydrophobicContact CG1-CD1 3.95Å; I719-L738 HydrophobicContact CG1-CD2 3.91Å; I719-Q756 HydrophobicContact CD1-CB 4.17Å; I719-I757 HydrophobicContact CD1-CG1 4.03Å; I719-L760 HydrophobicContact CB-CD1 3.68Å; I719-L760 HydrophobicContact CD1-CD1 4Å; I719-L760 HydrophobicContact CG1-CD1 4.46Å; I719-L760 HydrophobicContact CG2-CD1 3.38Å
720I95.8Very high94.7Very high44 Ų4457.8 Ų57.823%0.22627%0.269CS..Hα-helixtrans-60.6-42178.7-69.6169.9000110.9Q716 E717 M723 K724 L760 Y765 Y778Q716-I720 WeakPolarHBondContact O-CG1 3.48Å; Q716-I720 PolarHBondContact O-N 2.86Å; E717-I720 PolarHBondContact O-N 3.23Å; I720-M723 PolarHBondContact O-N 3.5Å; I720-K724 VanDerWaalsContact O-CB 3.23Å; I720-K724 WeakPolarHBondContact O-CB 3.47Å; I720-K724 PolarHBondContact O-N 3.25Å; I720-L760 HydrophobicContact CD1-CD2 3.74Å; I720-L760 HydrophobicContact CG1-CD1 4.46Å; I720-L760 HydrophobicContact CG1-CD2 3.82Å; I720-Y765 HydrophobicContact CD1-CD1 4.21Å; I720-Y765 HydrophobicContact CD1-CE1 4.44Å; I720-Y765 HydrophobicContact CD1-CG 4.35Å; I720-Y778 HydrophobicContact CG2-CE2 4.42Å
721Q95Very high95Very high121 Ų12157 Ų5757%0.56527%0.265SS*.Hα-helixtrans-61.2-47.3178-175.6178.8-13.300111.9E717 A718 I719 M725E717-Q721 WeakPolarHBondContact O-CB 3.47Å; E717-Q721 PolarHBondContact O-N 3.26Å; A718-Q721 PolarHBondContact O-N 3.42Å; I719-Q721 VanDerWaalsContact C-N 3.31Å; I719-Q721 PolarHBondContact O-N 3.2Å; Q721-M725 PolarHBondContact O-N 3.36Å
722I96.4Very high95.2Very high6 Ų659.6 Ų59.63%0.03129%0.289CS..Hα-helixtrans-60.9-49.8176.1-66.1163.4000110.2A718 I719 K724 M725 R726 I729 L734 E737 L738 I741A718-I722 WeakPolarHBondContact O-CG1 3.31Å; A718-I722 PolarHBondContact O-N 3.25Å; I719-I722 PolarHBondContact O-N 3.48Å; I722-K724 VanDerWaalsContact C-N 3.33Å; I722-K724 PolarHBondContact O-N 3Å; I722-M725 PolarHBondContact O-N 3.18Å; I722-M725 VanDerWaalsContact O-N 3.12Å; I722-R726 HydrophobicContact CG2-CG 4.14Å; I722-R726 WeakPolarHBondContact O-CG 3.41Å; I722-R726 PolarHBondContact O-N 3Å; I722-I729 HydrophobicContact CG2-CD1 3.82Å; I722-L734 HydrophobicContact CB-CD1 4.12Å; I722-L734 HydrophobicContact CD1-CD1 4.03Å; I722-L734 HydrophobicContact CG2-CD1 3.77Å; I722-E737 HydrophobicContact CD1-CB 3.81Å; I722-E737 HydrophobicContact CG1-CB 4.29Å; I722-E737 HydrophobicContact CG2-CB 4.45Å; I722-L738 HydrophobicContact CD1-CB 4.11Å; I722-L738 HydrophobicContact CD1-CD1 4.5Å; I722-I741 HydrophobicContact CD1-CD1 3.8Å; I722-I741 HydrophobicContact CG1-CD1 3.64Å
723M95.8Very high95.3Very high0 Ų063.5 Ų63.50%031%0.306CS..Hα-helixtrans-62.6-39.6-177.3-71.6-65.6-56.400112.1I719 I720 M725 K727 I729 I766 F776 I777 Y778I719-M723 HydrophobicContact CG2-CG 3.99Å; I719-M723 VanDerWaalsContact O-CB 3.3Å; I719-M723 WeakPolarHBondContact O-CB 3.49Å; I719-M723 WeakPolarHBondContact O-CG 3.25Å; I719-M723 PolarHBondContact O-N 2.91Å; I720-M723 PolarHBondContact O-N 3.5Å; M723-M725 VanDerWaalsContact C-N 3.29Å; M723-M725 PolarHBondContact O-N 3.27Å; M723-K727 VanDerWaalsContact O-CA 3.31Å; M723-K727 WeakPolarHBondContact O-CA 3.4Å; M723-K727 PolarHBondContact O-N 3.12Å; M723-I729 HydrophobicContact CE-CG2 4.44Å; M723-I729 HydrophobicContact SD-CG2 3.36Å; M723-I729 WeakPolarHBondContact SD-CG2 3.35Å; M723-I766 HydrophobicContact CB-CG2 4.04Å; M723-I766 HydrophobicContact CE-CB 4.06Å; M723-I766 HydrophobicContact CE-CG2 3.58Å; M723-I766 HydrophobicContact CG-CG2 3.77Å; M723-I766 HydrophobicContact SD-CG2 4.31Å; M723-F776 HydrophobicContact CE-CB 3.65Å; M723-F776 HydrophobicContact SD-CB 4.01Å; M723-I777 VanDerWaalsContact CE-C 3.43Å; M723-Y778 HydrophobicContact CB-CD2 3.73Å; M723-Y778 HydrophobicContact CB-CE2 4.49Å; M723-Y778 HydrophobicContact CB-CG 4.25Å; M723-Y778 WeakPolarHBondContact O-CB 3.49Å
724K95.5Very high95.4Very high128 Ų12858.7 Ų58.756%0.55728%0.281SS*.Hα-helixtrans-63.2-36.2176-174.3173.2-180177.70112.2I720 I722 K727 Y778I720-K724 VanDerWaalsContact O-CB 3.23Å; I720-K724 WeakPolarHBondContact O-CB 3.47Å; I720-K724 PolarHBondContact O-N 3.25Å; I722-K724 VanDerWaalsContact C-N 3.33Å; I722-K724 PolarHBondContact O-N 3Å; K724-K727 WeakPolarHBondContact O-CD 3.4Å; K724-K727 WeakPolarHBondContact O-CE 3.15Å; K724-K727 PolarHBondContact O-NZ 3.43Å; K724-Y778 HydrophobicContact CB-CD1 4.48Å; K724-Y778 HydrophobicContact CB-CE1 3.89Å; K724-Y778 HydrophobicContact CB-CE2 4.36Å; K724-Y778 HydrophobicContact CG-CE1 3.88Å
725M95.6Very high95.5Very high147 Ų14759 Ų5972%0.72429%0.285SS*.Hα-helixtrans-77.6-46.1179.2-174.9177.8-179.700112.6Q721 I722 M723Q721-M725 PolarHBondContact O-N 3.36Å; I722-M725 PolarHBondContact O-N 3.18Å; I722-M725 VanDerWaalsContact O-N 3.12Å; M723-M725 VanDerWaalsContact C-N 3.29Å; M723-M725 PolarHBondContact O-N 3.27Å
726R95.4Very high95.5Very high126 Ų12663.4 Ų63.448%0.47531%0.312SS..Hα-helixtrans-85.1-27.3-173.2-62-67.9-168-167.52.6113.5I722 K728 I729 E737I722-R726 HydrophobicContact CG2-CG 4.14Å; I722-R726 WeakPolarHBondContact O-CG 3.41Å; I722-R726 PolarHBondContact O-N 3Å; R726-K728 PolarHBondContact O-N 2.87Å; R726-I729 HydrophobicContact CB-CB 4.31Å; R726-I729 HydrophobicContact CG-CD1 4.2Å; R726-E737 IonicContact CZ-OE1 3.19Å; R726-E737 IonicContact CZ-OE2 3.57Å; R726-E737 IonicContact NE-OE1 2.83Å; R726-E737 PolarHBondContact NE-OE1 3.35Å; R726-E737 IonicContact NE-OE2 3.65Å; R726-E737 PolarHBondContact NE-OE2 2.93Å; R726-E737 IonicContact NH2-OE1 3.75Å; R726-E737 PolarHBondContact NH2-OE1 3.36Å; R726-E737 IonicContact NH2-OE2 3.61Å
727K94.6Very high95.6Very high105 Ų10564.7 Ų64.746%0.45732%0.318SS..SBendtrans62.4-38.1-173.7-55.9-59.4-171.5179.90115.5M723 K724 I777 Y778M723-K727 VanDerWaalsContact O-CA 3.31Å; M723-K727 WeakPolarHBondContact O-CA 3.4Å; M723-K727 PolarHBondContact O-N 3.12Å; K724-K727 WeakPolarHBondContact O-CD 3.4Å; K724-K727 WeakPolarHBondContact O-CE 3.15Å; K724-K727 PolarHBondContact O-NZ 3.43Å; K727-I777 WeakPolarHBondContact O-CA 3.19Å; K727-Y778 HydrophobicContact CD-CD1 4.01Å; K727-Y778 PolarHBondContact O-N 3.32Å
728K96Very high95.6Very high117 Ų11759.9 Ų59.951%0.50930%0.296SS..EExtended strand (participates in β ladder)trans-139.1129.1173.4-176.6169.6174165.90109.2R726 D769 T775 F776 I777R726-K728 PolarHBondContact O-N 2.87Å; K728-D769 WeakPolarHBondContact CE-OD2 3.41Å; K728-D769 IonicContact NZ-OD2 3.31Å; K728-D769 PolarHBondContact NZ-OD2 3.31Å; K728-T775 HydrophobicContact CD-CG2 4.17Å; K728-T775 VanDerWaalsContact CE-CG2 3.47Å; K728-T775 HydrophobicContact CG-CG2 3.61Å; K728-F776 VanDerWaalsContact CA-O 3.31Å; K728-F776 WeakPolarHBondContact CA-O 3.27Å; K728-I777 HydrophobicContact CG-CG1 4.37Å
729I96.6Very high95.6Very high6 Ų661.8 Ų61.83%0.03131%0.307CS..EExtended strand (participates in β ladder)trans-150.8145.2-177.7-167.9170.1000111.1I722 M723 R726 Q733 L734 F776I722-I729 HydrophobicContact CG2-CD1 3.82Å; M723-I729 HydrophobicContact CE-CG2 4.44Å; M723-I729 HydrophobicContact SD-CG2 3.36Å; M723-I729 WeakPolarHBondContact SD-CG2 3.35Å; R726-I729 HydrophobicContact CB-CB 4.31Å; R726-I729 HydrophobicContact CG-CD1 4.2Å; I729-Q733 HydrophobicContact CD1-CB 3.86Å; I729-Q733 HydrophobicContact CG1-CB 3.62Å; I729-L734 HydrophobicContact CD1-CB 4.15Å; I729-L734 HydrophobicContact CG1-CB 4.41Å; I729-L734 HydrophobicContact CG2-CB 4.13Å; I729-L734 HydrophobicContact CG2-CD1 4.47Å; I729-F776 PolarHBondContact N-O 3.15Å; I729-F776 PolarHBondContact O-N 2.93Å
730S96.6Very high95.4Very high33 Ų3366.8 Ų66.823%0.23133%0.33CS..EExtended strand (participates in β ladder)trans-76.1155.8172.567.90000111.8A732 Q733 L734 N774S730-A732 VanDerWaalsContact C-N 3.29Å; S730-A732 PolarHBondContact O-N 2.85Å; S730-Q733 PolarHBondContact O-N 3.07Å; S730-Q733 WeakPolarHBondContact OG-CB 3.4Å; S730-Q733 VanDerWaalsContact OG-CD 3.31Å; S730-Q733 VanDerWaalsContact OG-CG 3.29Å; S730-Q733 WeakPolarHBondContact OG-CG 3.41Å; S730-Q733 PolarHBondContact OG-N 3.18Å; S730-Q733 PolarHBondContact OG-OE1 3.39Å; S730-L734 WeakPolarHBondContact O-CB 3.44Å; S730-L734 PolarHBondContact O-N 2.96Å; S730-N774 CarbonylContact C-O 3.6Å; S730-N774 WeakPolarHBondContact CA-O 3.38Å
731N94.5Very high95.2Very high42 Ų4268.1 Ų68.123%0.22534%0.337CS..Hα-helixtrans-59.3-39.4179.9-177.1-85.2000112.2L734 Q735 N774 F776N731-L734 PolarHBondContact O-N 3.02Å; N731-Q735 WeakPolarHBondContact O-CG 3.17Å; N731-Q735 PolarHBondContact O-N 3.48Å; N731-Q735 PolarHBondContact OD1-NE2 3.22Å; N731-N774 WeakPolarHBondContact CB-O 3.25Å; N731-N774 PolarHBondContact N-O 3.4Å; N731-F776 HydrophobicContact CB-CE2 3.82Å; N731-F776 HydrophobicContact CB-CZ 4.36Å; N731-F776 VanDerWaalsContact ND2-CE2 3.32Å; N731-F776 WeakPolarHBondContact ND2-CE2 3.48Å; N731-F776 WeakPolarHBondContact ND2-CZ 3.37Å
732A94.8Very high95.1Very high67 Ų6762.5 Ų62.555%0.55431%0.311SS*.Hα-helixtrans-63.6-48.2177.400000111.6S730 L734 Q735 T736S730-A732 VanDerWaalsContact C-N 3.29Å; S730-A732 PolarHBondContact O-N 2.85Å; A732-L734 PolarHBondContact O-N 3.12Å; A732-Q735 PolarHBondContact O-N 3.28Å; A732-T736 PolarHBondContact O-N 3.35Å; A732-T736 PolarHBondContact O-OG1 3.31Å
733Q95.7Very high94.8Very high112 Ų11266.2 Ų66.252%0.52333%0.327SS..Hα-helixtrans-64.5-40.7177.8-72.1169.6-3800111.9I729 S730 Q735 T736 E737I729-Q733 HydrophobicContact CD1-CB 3.86Å; I729-Q733 HydrophobicContact CG1-CB 3.62Å; S730-Q733 PolarHBondContact O-N 3.07Å; S730-Q733 WeakPolarHBondContact OG-CB 3.4Å; S730-Q733 VanDerWaalsContact OG-CD 3.31Å; S730-Q733 VanDerWaalsContact OG-CG 3.29Å; S730-Q733 WeakPolarHBondContact OG-CG 3.41Å; S730-Q733 PolarHBondContact OG-N 3.18Å; S730-Q733 PolarHBondContact OG-OE1 3.39Å; Q733-Q735 VanDerWaalsContact C-N 3.34Å; Q733-Q735 PolarHBondContact O-N 3.06Å; Q733-T736 PolarHBondContact O-N 3.3Å; Q733-E737 PolarHBondContact O-N 3.44Å
734L96Very high94.3Very high0 Ų070.2 Ų70.20%035%0.348CS..Hα-helixtrans-59.6-45.5175.917862.8000111.1I719 I722 I729 S730 N731 A732 L738 I757 F776I719-L734 HydrophobicContact CG2-CD1 4.35Å; I719-L734 HydrophobicContact CG2-CD2 4.35Å; I722-L734 HydrophobicContact CB-CD1 4.12Å; I722-L734 HydrophobicContact CD1-CD1 4.03Å; I722-L734 HydrophobicContact CG2-CD1 3.77Å; I729-L734 HydrophobicContact CD1-CB 4.15Å; I729-L734 HydrophobicContact CG1-CB 4.41Å; I729-L734 HydrophobicContact CG2-CB 4.13Å; I729-L734 HydrophobicContact CG2-CD1 4.47Å; S730-L734 WeakPolarHBondContact O-CB 3.44Å; S730-L734 PolarHBondContact O-N 2.96Å; N731-L734 PolarHBondContact O-N 3.02Å; A732-L734 PolarHBondContact O-N 3.12Å; L734-L738 WeakPolarHBondContact O-CB 3.22Å; L734-L738 PolarHBondContact O-N 3.12Å; L734-I757 HydrophobicContact CD2-CD1 3.89Å; L734-I757 HydrophobicContact CD2-CG1 4.32Å; L734-F776 HydrophobicContact CD2-CD2 3.75Å; L734-F776 HydrophobicContact CD2-CE2 3.94Å
735Q94.9Very high94.1Very high58 Ų5865 Ų6527%0.27133%0.326SS..Hα-helixtrans-62.5-42.4177.4-74.2-17245.100112N731 A732 Q733 L738 V739 I753N731-Q735 WeakPolarHBondContact O-CG 3.17Å; N731-Q735 PolarHBondContact O-N 3.48Å; N731-Q735 PolarHBondContact OD1-NE2 3.22Å; A732-Q735 PolarHBondContact O-N 3.28Å; Q733-Q735 VanDerWaalsContact C-N 3.34Å; Q733-Q735 PolarHBondContact O-N 3.06Å; Q735-L738 PolarHBondContact O-N 3.23Å; Q735-V739 WeakPolarHBondContact O-CG2 3.25Å; Q735-V739 PolarHBondContact O-N 3.11Å; Q735-I753 HydrophobicContact CG-CG2 4.29Å
736T95.5Very high93.9Very high93 Ų9358.1 Ų58.157%0.57129%0.292SS*.Hα-helixtrans-62.4-50.7177.2-58.60000111.7A732 Q733 L738 V739 E740A732-T736 PolarHBondContact O-N 3.35Å; A732-T736 PolarHBondContact O-OG1 3.31Å; Q733-T736 PolarHBondContact O-N 3.3Å; T736-L738 VanDerWaalsContact C-N 3.32Å; T736-L738 PolarHBondContact O-N 2.89Å; T736-V739 PolarHBondContact O-N 2.86Å; T736-E740 WeakPolarHBondContact O-CG 3.24Å; T736-E740 PolarHBondContact O-N 2.87Å; T736-E740 VanDerWaalsContact O-N 3.1Å
737E96.1Very high93.6Very high49 Ų4955.6 Ų55.623%0.22929%0.288CS..Hα-helixtrans-64-37.9178.7-70.2-169.3-158.900111.7I722 R726 Q733 E740 I741I722-E737 HydrophobicContact CD1-CB 3.81Å; I722-E737 HydrophobicContact CG1-CB 4.29Å; I722-E737 HydrophobicContact CG2-CB 4.45Å; R726-E737 IonicContact CZ-OE1 3.19Å; R726-E737 IonicContact CZ-OE2 3.57Å; R726-E737 IonicContact NE-OE1 2.83Å; R726-E737 PolarHBondContact NE-OE1 3.35Å; R726-E737 IonicContact NE-OE2 3.65Å; R726-E737 PolarHBondContact NE-OE2 2.93Å; R726-E737 IonicContact NH2-OE1 3.75Å; R726-E737 PolarHBondContact NH2-OE1 3.36Å; R726-E737 IonicContact NH2-OE2 3.61Å; Q733-E737 PolarHBondContact O-N 3.44Å; E737-E740 PolarHBondContact O-N 2.87Å; E737-I741 WeakPolarHBondContact O-CG1 3.38Å; E737-I741 PolarHBondContact O-N 2.92Å
738L96.1Very high93.3Very high0 Ų051 Ų510%027%0.268CS..Hα-helixtrans-64.2-44.3178.3-178.662.9000112.4T715 A718 I719 I722 L734 Q735 T736 E740 I741 L742 I753T715-L738 HydrophobicContact CG2-CD2 4.22Å; A718-L738 HydrophobicContact CB-CD1 3.51Å; I719-L738 HydrophobicContact CD1-CD2 4.18Å; I719-L738 HydrophobicContact CG1-CD1 3.95Å; I719-L738 HydrophobicContact CG1-CD2 3.91Å; I722-L738 HydrophobicContact CD1-CB 4.11Å; I722-L738 HydrophobicContact CD1-CD1 4.5Å; L734-L738 WeakPolarHBondContact O-CB 3.22Å; L734-L738 PolarHBondContact O-N 3.12Å; Q735-L738 PolarHBondContact O-N 3.23Å; T736-L738 VanDerWaalsContact C-N 3.32Å; T736-L738 PolarHBondContact O-N 2.89Å; L738-E740 VanDerWaalsContact C-N 3.32Å; L738-I741 PolarHBondContact O-N 3.23Å; L738-L742 HydrophobicContact CD1-CD1 3.53Å; L738-L742 HydrophobicContact CD1-CG 4.13Å; L738-L742 HydrophobicContact CG-CD1 3.96Å; L738-L742 WeakPolarHBondContact O-CB 3.49Å; L738-L742 WeakPolarHBondContact O-CG 3.48Å; L738-L742 PolarHBondContact O-N 3.02Å; L738-I753 HydrophobicContact CD2-CB 4.4Å; L738-I753 HydrophobicContact CD2-CD1 4.05Å; L738-I753 HydrophobicContact CD2-CG1 3.79Å; L738-I753 HydrophobicContact CD2-CG2 3.84Å
739V93.5Very high92.9Very high44 Ų4448.2 Ų48.227%0.26726%0.257SS..Hα-helixtrans-63.7-40.8176.1169.90000110.4Q735 T736 I741 L742 K743 L747 P748Q735-V739 WeakPolarHBondContact O-CG2 3.25Å; Q735-V739 PolarHBondContact O-N 3.11Å; T736-V739 PolarHBondContact O-N 2.86Å; V739-I741 VanDerWaalsContact C-N 3.34Å; V739-I741 PolarHBondContact O-N 3.2Å; V739-L742 PolarHBondContact O-N 3.38Å; V739-K743 WeakPolarHBondContact O-CB 3.42Å; V739-K743 PolarHBondContact O-N 3.25Å; V739-L747 HydrophobicContact CG1-CD1 3.91Å; V739-P748 HydrophobicContact CG2-CG 4.12Å
740E92.6Very high92.6Very high104 Ų10456.1 Ų56.149%0.48629%0.291SS..Hα-helixtrans-63-37.1178.2-75.9-65.1112.200113.2T736 E737 L738 K743T736-E740 WeakPolarHBondContact O-CG 3.24Å; T736-E740 PolarHBondContact O-N 2.87Å; T736-E740 VanDerWaalsContact O-N 3.1Å; E737-E740 PolarHBondContact O-N 2.87Å; L738-E740 VanDerWaalsContact C-N 3.32Å; E740-K743 IonicContact OE1-NZ 2.75Å; E740-K743 PolarHBondContact OE1-NZ 2.92Å; E740-K743 WeakPolarHBondContact OE2-CE 3.22Å; E740-K743 IonicContact OE2-NZ 3.57Å; E740-K743 PolarHBondContact OE2-NZ 2.81Å
741I92.3Very high92.2Very high72 Ų7259.7 Ų59.737%0.36930%0.303SS..Hα-helixtrans-70.8-44.5174.9-66.9176.3000111.1A718 I722 E737 L738 V739A718-I741 HydrophobicContact CB-CG2 4.11Å; I722-I741 HydrophobicContact CD1-CD1 3.8Å; I722-I741 HydrophobicContact CG1-CD1 3.64Å; E737-I741 WeakPolarHBondContact O-CG1 3.38Å; E737-I741 PolarHBondContact O-N 2.92Å; L738-I741 PolarHBondContact O-N 3.23Å; V739-I741 VanDerWaalsContact C-N 3.34Å; V739-I741 PolarHBondContact O-N 3.2Å
742L93Very high92Very high3 Ų358.6 Ų58.62%0.01630%0.297CS..Hα-helixtrans-88.5-20-169.6-65.6177.6000114.6R714 A718 L738 V739 N744 M745 F746 P748R714-L742 HydrophobicContact CB-CD2 4.37Å; A718-L742 HydrophobicContact CB-CD1 4.42Å; A718-L742 HydrophobicContact CB-CD2 4.1Å; A718-L742 HydrophobicContact CB-CG 4.25Å; L738-L742 HydrophobicContact CD1-CD1 3.53Å; L738-L742 HydrophobicContact CD1-CG 4.13Å; L738-L742 HydrophobicContact CG-CD1 3.96Å; L738-L742 WeakPolarHBondContact O-CB 3.49Å; L738-L742 WeakPolarHBondContact O-CG 3.48Å; L738-L742 PolarHBondContact O-N 3.02Å; V739-L742 PolarHBondContact O-N 3.38Å; L742-N744 PolarHBondContact O-N 2.81Å; L742-M745 HydrophobicContact CD2-SD 4.48Å; L742-M745 WeakPolarHBondContact O-CA 3.5Å; L742-M745 WeakPolarHBondContact O-CB 3.33Å; L742-M745 PolarHBondContact O-N 3.21Å; L742-F746 CarbonylContact C-O 3.58Å; L742-F746 VanDerWaalsContact C-O 3.28Å; L742-F746 HydrophobicContact CD1-CE2 4.23Å; L742-F746 HydrophobicContact CD1-CZ 3.87Å; L742-F746 HydrophobicContact CD2-CE1 4.19Å; L742-F746 HydrophobicContact CD2-CZ 4.2Å; L742-F746 HydrophobicContact CG-CZ 4.44Å; L742-F746 PolarHBondContact O-N 3.25Å; L742-P748 HydrophobicContact CB-CG 4.33Å; L742-P748 HydrophobicContact CD1-CB 4.14Å; L742-P748 HydrophobicContact CD1-CG 3.97Å
743K89.1Confident91.9Very high85 Ų8555.6 Ų55.637%0.3727%0.271SS..THydrogen-bonded Turntrans-56-23.2-173.565.4-178.3176.6-174.50115.5V739 E740 M745V739-K743 WeakPolarHBondContact O-CB 3.42Å; V739-K743 PolarHBondContact O-N 3.25Å; E740-K743 IonicContact OE1-NZ 2.75Å; E740-K743 PolarHBondContact OE1-NZ 2.92Å; E740-K743 WeakPolarHBondContact OE2-CE 3.22Å; E740-K743 IonicContact OE2-NZ 3.57Å; E740-K743 PolarHBondContact OE2-NZ 2.81Å; K743-M745 VanDerWaalsContact C-N 3.31Å
744N86.1Confident91.8Very high83 Ų8357 Ų5744%0.44428%0.275SS..THydrogen-bonded Turntrans-80.7-13.8176.6-66.8-27.7000112.8K447 L742K447-N744 VanDerWaalsContact CD-O 3.3Å; K447-N744 WeakPolarHBondContact CD-O 3.42Å; L742-N744 PolarHBondContact O-N 2.81Å
745M91Very high91.6Very high20 Ų2060.8 Ų60.810%0.09929%0.293CS..THydrogen-bonded Turntrans-103.2-58.8175.7-61.2-177.257.800111.5K447 D448 P486 Y489 R714 L742 K743K447-M745 PolarHBondContact N-O 2.82Å; D448-M745 PolarHBondContact N-O 3.22Å; P486-M745 HydrophobicContact CB-CG 4.41Å; P486-M745 HydrophobicContact CG-CB 4.48Å; P486-M745 HydrophobicContact CG-CG 3.46Å; P486-M745 VanDerWaalsContact CG-CG 3.46Å; P486-M745 HydrophobicContact CG-SD 4.39Å; Y489-M745 HydrophobicContact CE2-CE 4.15Å; Y489-M745 WeakPolarHBondContact OH-CE 3.48Å; R714-M745 HydrophobicContact CB-CE 4.4Å; R714-M745 HydrophobicContact CG-CE 3.73Å; L742-M745 HydrophobicContact CD2-SD 4.48Å; L742-M745 WeakPolarHBondContact O-CA 3.5Å; L742-M745 WeakPolarHBondContact O-CB 3.33Å; L742-M745 PolarHBondContact O-N 3.21Å; K743-M745 VanDerWaalsContact C-N 3.31Å
746F92.1Very high91.6Very high1 Ų158.6 Ų58.60%0.00428%0.283CS..  trans-162.2159.7-177.165.7-88.8000109.7Q445 R711 R714 L742 P748 M752Q445-F746 WeakPolarHBondContact O-CA 3.5Å; R711-F746 HydrophobicContact CB-CD2 4.45Å; R711-F746 HydrophobicContact CB-CE1 4.12Å; R711-F746 HydrophobicContact CB-CE2 4.02Å; R711-F746 HydrophobicContact CB-CZ 3.83Å; R711-F746 HydrophobicContact CG-CD1 3.79Å; R711-F746 HydrophobicContact CG-CD2 3.97Å; R711-F746 HydrophobicContact CG-CE1 3.83Å; R711-F746 HydrophobicContact CG-CE2 4.02Å; R711-F746 HydrophobicContact CG-CG 3.87Å; R711-F746 HydrophobicContact CG-CZ 3.94Å; R714-F746 HydrophobicContact CB-CE1 4.06Å; R714-F746 HydrophobicContact CB-CZ 4.39Å; L742-F746 CarbonylContact C-O 3.58Å; L742-F746 VanDerWaalsContact C-O 3.28Å; L742-F746 HydrophobicContact CD1-CE2 4.23Å; L742-F746 HydrophobicContact CD1-CZ 3.87Å; L742-F746 HydrophobicContact CD2-CE1 4.19Å; L742-F746 HydrophobicContact CD2-CZ 4.2Å; L742-F746 HydrophobicContact CG-CZ 4.44Å; L742-F746 PolarHBondContact O-N 3.25Å; F746-P748 HydrophobicContact CD2-CB 4.46Å; F746-P748 HydrophobicContact CE2-CB 3.86Å; F746-P748 VanDerWaalsContact O-CD 3.3Å; F746-P748 WeakPolarHBondContact O-CD 3.32Å; F746-M752 HydrophobicContact CD2-CE 4.35Å; F746-M752 HydrophobicContact CE2-CE 3.47Å; F746-M752 VanDerWaalsContact CE2-CE 3.47Å; F746-M752 HydrophobicContact CZ-CE 4.14Å
747L89.2Confident91.6Very high74 Ų7454.4 Ų54.439%0.38726%0.257SS..  trans-90.3110173.5-171.365.8000110.1N446 V739 Q749N446-L747 PolarHBondContact OD1-N 2.98Å; N446-L747 VanDerWaalsContact OD1-N 3.17Å; V739-L747 HydrophobicContact CG1-CD1 3.91Å; L747-Q749 PolarHBondContact O-N 3Å
748P88.5Confident91.5Very high8 Ų855.5 Ų55.55%0.05226%0.262CS..  trans-65.2126.6-178.826.7-35.9000111.3V739 L742 F746 M752 I753V739-P748 HydrophobicContact CG2-CG 4.12Å; L742-P748 HydrophobicContact CB-CG 4.33Å; L742-P748 HydrophobicContact CD1-CB 4.14Å; L742-P748 HydrophobicContact CD1-CG 3.97Å; F746-P748 HydrophobicContact CD2-CB 4.46Å; F746-P748 HydrophobicContact CE2-CB 3.86Å; F746-P748 VanDerWaalsContact O-CD 3.3Å; F746-P748 WeakPolarHBondContact O-CD 3.32Å; P748-M752 HydrophobicContact CB-CE 3.96Å; P748-I753 HydrophobicContact CB-CD1 4.02Å; P748-I753 HydrophobicContact CB-CG1 3.9Å; P748-I753 HydrophobicContact CG-CD1 4.08Å; P748-I753 HydrophobicContact CG-CG1 4.45Å
749Q87.4Confident91.5Very high59 Ų5959.6 Ų59.628%0.27628%0.278SS..  trans-69139.7177.2-61.4-178.612.100110.5E401 L747 K751 M752 I753E401-Q749 PolarHBondContact OE1-NE2 3.1Å; L747-Q749 PolarHBondContact O-N 3Å; Q749-K751 PolarHBondContact O-N 3.09Å; Q749-K751 VanDerWaalsContact O-N 3.09Å; Q749-M752 HydrophobicContact CB-CB 4.4Å; Q749-M752 WeakPolarHBondContact O-CB 3.34Å; Q749-M752 PolarHBondContact O-N 3.26Å; Q749-I753 PolarHBondContact O-N 2.93Å
750K89Confident91.6Very high172 Ų17257.5 Ų57.575%0.74827%0.265SS*.Hα-helixtrans-51.1-38.6178.9-68.9-173.2178.6-1780113.1I753 K754K750-I753 PolarHBondContact O-N 2.78Å; K750-K754 PolarHBondContact O-N 2.83Å; K750-K754 VanDerWaalsContact O-N 3.09Å
751K89.8Confident91.7Very high107 Ų10754.3 Ų54.347%0.46525%0.251SS..Hα-helixtrans-62.2-48.5176.4-178.5174.8176.7176.70111.9Q749 I753 K754 E755Q749-K751 PolarHBondContact O-N 3.09Å; Q749-K751 VanDerWaalsContact O-N 3.09Å; K751-I753 VanDerWaalsContact C-N 3.34Å; K751-I753 PolarHBondContact O-N 3.05Å; K751-K754 PolarHBondContact O-N 2.83Å; K751-E755 WeakPolarHBondContact CE-OE1 3.48Å; K751-E755 WeakPolarHBondContact CG-OE1 3.34Å; K751-E755 WeakPolarHBondContact O-CG 3.1Å; K751-E755 PolarHBondContact O-N 3.26Å
752M89.9Confident91.8Very high20 Ų2057.9 Ų57.910%0.09927%0.266CS..Hα-helixtrans-61.4-42.9177.4-174.917272.500111.4R711 I712 T715 F746 P748 Q749 K754 E755 Q756R711-M752 HydrophobicContact CB-CE 4.12Å; R711-M752 HydrophobicContact CB-SD 4.08Å; I712-M752 HydrophobicContact CG1-SD 4.27Å; T715-M752 VanDerWaalsContact OG1-CE 3.24Å; T715-M752 WeakPolarHBondContact OG1-CE 3.41Å; F746-M752 HydrophobicContact CD2-CE 4.35Å; F746-M752 HydrophobicContact CE2-CE 3.47Å; F746-M752 VanDerWaalsContact CE2-CE 3.47Å; F746-M752 HydrophobicContact CZ-CE 4.14Å; P748-M752 HydrophobicContact CB-CE 3.96Å; Q749-M752 HydrophobicContact CB-CB 4.4Å; Q749-M752 WeakPolarHBondContact O-CB 3.34Å; Q749-M752 PolarHBondContact O-N 3.26Å; M752-K754 VanDerWaalsContact C-N 3.33Å; M752-K754 PolarHBondContact O-N 2.93Å; M752-E755 PolarHBondContact O-N 2.91Å; M752-Q756 HydrophobicContact CG-CG 4.25Å; M752-Q756 VanDerWaalsContact O-CG 3.28Å; M752-Q756 WeakPolarHBondContact O-CG 3.28Å; M752-Q756 PolarHBondContact O-N 3.08Å
753I92.7Very high91.9Very high4 Ų462 Ų622%0.02129%0.285CS..Hα-helixtrans-57.5-48.2176.6-62169.8000110.5Q735 L738 P748 Q749 K750 K751 Q756 I757Q735-I753 HydrophobicContact CG-CG2 4.29Å; L738-I753 HydrophobicContact CD2-CB 4.4Å; L738-I753 HydrophobicContact CD2-CD1 4.05Å; L738-I753 HydrophobicContact CD2-CG1 3.79Å; L738-I753 HydrophobicContact CD2-CG2 3.84Å; P748-I753 HydrophobicContact CB-CD1 4.02Å; P748-I753 HydrophobicContact CB-CG1 3.9Å; P748-I753 HydrophobicContact CG-CD1 4.08Å; P748-I753 HydrophobicContact CG-CG1 4.45Å; Q749-I753 PolarHBondContact O-N 2.93Å; K750-I753 PolarHBondContact O-N 2.78Å; K751-I753 VanDerWaalsContact C-N 3.34Å; K751-I753 PolarHBondContact O-N 3.05Å; I753-Q756 PolarHBondContact O-N 3.06Å; I753-I757 HydrophobicContact CG2-CD1 3.8Å; I753-I757 HydrophobicContact CG2-CG1 4.44Å; I753-I757 VanDerWaalsContact O-CG1 3.31Å; I753-I757 WeakPolarHBondContact O-CG1 3.33Å; I753-I757 PolarHBondContact O-N 2.78Å
754K92.6Very high92.1Very high141 Ų14165.4 Ų65.461%0.61330%0.3SS*.Hα-helixtrans-59.7-48.8178.4-173.1-178.7178.6-177.20111.5K750 K751 M752 Q756 I757 E758K750-K754 PolarHBondContact O-N 2.83Å; K750-K754 VanDerWaalsContact O-N 3.09Å; K751-K754 PolarHBondContact O-N 2.83Å; M752-K754 VanDerWaalsContact C-N 3.33Å; M752-K754 PolarHBondContact O-N 2.93Å; K754-Q756 VanDerWaalsContact C-N 3.33Å; K754-Q756 PolarHBondContact O-N 3.27Å; K754-I757 PolarHBondContact O-N 2.93Å; K754-E758 WeakPolarHBondContact O-CG 3.13Å; K754-E758 PolarHBondContact O-N 2.85Å
755E93.4Very high92.5Very high79 Ų7965.9 Ų65.937%0.36930%0.296SS..Hα-helixtrans-59.7-41.9179.2-72.1168.4-17900112K751 M752 E758 W759K751-E755 WeakPolarHBondContact CE-OE1 3.48Å; K751-E755 WeakPolarHBondContact CG-OE1 3.34Å; K751-E755 WeakPolarHBondContact O-CG 3.1Å; K751-E755 PolarHBondContact O-N 3.26Å; M752-E755 PolarHBondContact O-N 2.91Å; E755-E758 PolarHBondContact O-N 3.04Å; E755-W759 WeakPolarHBondContact O-CB 3.11Å; E755-W759 PolarHBondContact O-N 3.46Å
756Q94.6Very high92.7Very high13 Ų1364.9 Ų64.96%0.06129%0.291CS..Hα-helixtrans-71.2-33178.3-61.9-32.6-61.100112.9T715 Q716 I719 M752 I753 K754 W759 L760T715-Q756 HydrophobicContact CG2-CB 4.01Å; T715-Q756 HydrophobicContact CG2-CG 3.83Å; Q716-Q756 HydrophobicContact CG-CB 4.27Å; Q716-Q756 HydrophobicContact CG-CG 4.23Å; I719-Q756 HydrophobicContact CD1-CB 4.17Å; M752-Q756 HydrophobicContact CG-CG 4.25Å; M752-Q756 VanDerWaalsContact O-CG 3.28Å; M752-Q756 WeakPolarHBondContact O-CG 3.28Å; M752-Q756 PolarHBondContact O-N 3.08Å; I753-Q756 PolarHBondContact O-N 3.06Å; K754-Q756 VanDerWaalsContact C-N 3.33Å; K754-Q756 PolarHBondContact O-N 3.27Å; Q756-W759 PolarHBondContact O-N 2.82Å; Q756-L760 WeakPolarHBondContact O-CB 3.43Å; Q756-L760 WeakPolarHBondContact O-CG 3.34Å; Q756-L760 PolarHBondContact O-N 2.98Å
757I94.4Very high92.8Very high5 Ų569.2 Ų69.23%0.02631%0.307CS..Hα-helixtrans-64.3-47.3172.5-71.4169.8000110.5I719 L734 I753 K754 W759 L760 I761 I766 F776I719-I757 HydrophobicContact CD1-CG1 4.03Å; L734-I757 HydrophobicContact CD2-CD1 3.89Å; L734-I757 HydrophobicContact CD2-CG1 4.32Å; I753-I757 HydrophobicContact CG2-CD1 3.8Å; I753-I757 HydrophobicContact CG2-CG1 4.44Å; I753-I757 VanDerWaalsContact O-CG1 3.31Å; I753-I757 WeakPolarHBondContact O-CG1 3.33Å; I753-I757 PolarHBondContact O-N 2.78Å; K754-I757 PolarHBondContact O-N 2.93Å; I757-W759 VanDerWaalsContact C-N 3.31Å; I757-W759 PolarHBondContact O-N 3.04Å; I757-L760 PolarHBondContact O-N 2.82Å; I757-I761 HydrophobicContact CG2-CD1 3.88Å; I757-I761 WeakPolarHBondContact O-CG1 3.19Å; I757-I761 PolarHBondContact O-N 2.66Å; I757-I766 HydrophobicContact CG2-CD1 4.25Å; I757-F776 HydrophobicContact CD1-CE2 4.11Å; I757-F776 HydrophobicContact CD1-CZ 4.27Å; I757-F776 HydrophobicContact CG2-CD1 4.47Å; I757-F776 HydrophobicContact CG2-CE1 3.73Å; I757-F776 HydrophobicContact CG2-CE2 4.28Å; I757-F776 HydrophobicContact CG2-CZ 3.62Å
758E94.7Very high93.1Very high72 Ų7269.6 Ų69.634%0.33630%0.304SS..Hα-helixtrans-60.6-43.2177.2-61.1-51.9153.400111.2K754 E755 L760 I761 E762 R768K754-E758 WeakPolarHBondContact O-CG 3.13Å; K754-E758 PolarHBondContact O-N 2.85Å; E755-E758 PolarHBondContact O-N 3.04Å; E758-L760 VanDerWaalsContact C-N 3.33Å; E758-L760 PolarHBondContact O-N 2.93Å; E758-I761 PolarHBondContact O-N 2.84Å; E758-I761 VanDerWaalsContact O-N 3.16Å; E758-E762 WeakPolarHBondContact O-CB 3.39Å; E758-E762 PolarHBondContact O-N 3.05Å; E758-R768 IonicContact OE1-CZ 3.84Å; E758-R768 IonicContact OE1-NH2 3.84Å; E758-R768 PolarHBondContact OE1-NH2 2.79Å; E758-R768 IonicContact OE2-CZ 3.94Å; E758-R768 IonicContact OE2-NH1 2.65Å; E758-R768 IonicContact OE2-NH2 2.8Å; E758-R768 PolarHBondContact OE2-NH2 3.07Å
759W95.3Very high93.3Very high86 Ų8670.2 Ų70.233%0.32631%0.307SS..Hα-helixtrans-58.8-44176.4-172.889.8000111.8Q716 E755 Q756 I757 I761 E762 H763 Y765Q716-W759 HydrophobicContact CG-CE3 4.26Å; Q716-W759 HydrophobicContact CG-CZ3 4.44Å; E755-W759 WeakPolarHBondContact O-CB 3.11Å; E755-W759 PolarHBondContact O-N 3.46Å; Q756-W759 PolarHBondContact O-N 2.82Å; I757-W759 VanDerWaalsContact C-N 3.31Å; I757-W759 PolarHBondContact O-N 3.04Å; W759-I761 VanDerWaalsContact C-N 3.33Å; W759-I761 PolarHBondContact O-N 3.23Å; W759-E762 PolarHBondContact O-N 2.95Å; W759-H763 AromaticContact CD1-CE1 3.57Å; W759-H763 AromaticContact CD1-ND1 3.85Å; W759-H763 AromaticContact CD2-CE1 3.94Å; W759-H763 AromaticContact CD2-ND1 3.65Å; W759-H763 AromaticContact CE2-CE1 3.36Å; W759-H763 AromaticContact CE2-CG 3.96Å; W759-H763 AromaticContact CE2-ND1 3.49Å; W759-H763 AromaticContact CE2-NE2 3.71Å; W759-H763 AromaticContact CG-ND1 3.89Å; W759-H763 AromaticContact CZ2-CD2 3.76Å; W759-H763 AromaticContact CZ2-CE1 3.81Å; W759-H763 AromaticContact CZ2-CG 3.93Å; W759-H763 AromaticContact CZ2-ND1 3.93Å; W759-H763 AromaticContact CZ2-NE2 3.68Å; W759-H763 AromaticContact NE1-CE1 3.12Å; W759-H763 PolarHBondContact NE1-CE1 2.84Å; W759-H763 AromaticContact NE1-ND1 3.63Å; W759-H763 AromaticContact NE1-NE2 3.68Å; W759-H763 WeakPolarHBondContact O-CB 3.28Å; W759-H763 PolarHBondContact O-N 3.3Å; W759-H763 PolarHBondContact O-ND1 3.29Å; W759-Y765 HydrophobicContact CH2-CE2 4.22Å; W759-Y765 HydrophobicContact CZ3-CD2 4.34Å; W759-Y765 AromaticContact CZ3-CE2 3.94Å; W759-Y765 HydrophobicContact CZ3-CE2 3.94Å
760L95.7Very high93.5Very high0 Ų075.5 Ų75.50%033%0.331CS..Hα-helixtrans-67.6-30.4177.6-71.8170.4000113.2I719 I720 Q756 I757 E758 K764 Y765 I766I719-L760 HydrophobicContact CB-CD1 3.68Å; I719-L760 HydrophobicContact CD1-CD1 4Å; I719-L760 HydrophobicContact CG1-CD1 4.46Å; I719-L760 HydrophobicContact CG2-CD1 3.38Å; I720-L760 HydrophobicContact CD1-CD2 3.74Å; I720-L760 HydrophobicContact CG1-CD1 4.46Å; I720-L760 HydrophobicContact CG1-CD2 3.82Å; Q756-L760 WeakPolarHBondContact O-CB 3.43Å; Q756-L760 WeakPolarHBondContact O-CG 3.34Å; Q756-L760 PolarHBondContact O-N 2.98Å; I757-L760 PolarHBondContact O-N 2.82Å; E758-L760 VanDerWaalsContact C-N 3.33Å; E758-L760 PolarHBondContact O-N 2.93Å; L760-K764 PolarHBondContact O-N 2.98Å; L760-Y765 HydrophobicContact CD2-CD2 3.62Å; L760-Y765 HydrophobicContact CD2-CE2 4.35Å; L760-Y765 HydrophobicContact CD2-CG 3.99Å; L760-Y765 PolarHBondContact O-N 3.21Å; L760-I766 HydrophobicContact CB-CD1 3.92Å; L760-I766 HydrophobicContact CB-CG1 3.92Å; L760-I766 PolarHBondContact O-N 3.24Å
761I94.8Very high93.6Very high36 Ų3672.2 Ų72.219%0.18533%0.33CS..Hα-helixtrans-69.9-48.9173-67.7166.4000110.3I757 E758 W759 H763 K764 I766 R768 F776I757-I761 HydrophobicContact CG2-CD1 3.88Å; I757-I761 WeakPolarHBondContact O-CG1 3.19Å; I757-I761 PolarHBondContact O-N 2.66Å; E758-I761 PolarHBondContact O-N 2.84Å; E758-I761 VanDerWaalsContact O-N 3.16Å; W759-I761 VanDerWaalsContact C-N 3.33Å; W759-I761 PolarHBondContact O-N 3.23Å; I761-H763 VanDerWaalsContact C-N 3.25Å; I761-H763 PolarHBondContact O-N 3.03Å; I761-K764 PolarHBondContact O-N 2.91Å; I761-I766 WeakPolarHBondContact CA-O 3.29Å; I761-I766 HydrophobicContact CG1-CD1 4.07Å; I761-I766 HydrophobicContact CG1-CG1 3.68Å; I761-R768 HydrophobicContact CD1-CG 4.03Å; I761-F776 HydrophobicContact CD1-CD1 4.48Å; I761-F776 HydrophobicContact CD1-CE1 4.16Å
762E95Very high93.7Very high148 Ų14869.9 Ų69.969%0.69232%0.322SS*.Hα-helixtrans-58.3-38.9178.8-173.4178.5-169.700111.7E758 W759 K764E758-E762 WeakPolarHBondContact O-CB 3.39Å; E758-E762 PolarHBondContact O-N 3.05Å; W759-E762 PolarHBondContact O-N 2.95Å; E762-K764 VanDerWaalsContact C-N 3.26Å; E762-K764 PolarHBondContact O-N 3.04Å
763H94.8Very high93.7Very high88 Ų8874.3 Ų74.341%0.40735%0.346SS..THydrogen-bonded Turntrans-86.911.2178.7-66.171.8000113.9W759 I761 Y765W759-H763 AromaticContact CD1-CE1 3.57Å; W759-H763 AromaticContact CD1-ND1 3.85Å; W759-H763 AromaticContact CD2-CE1 3.94Å; W759-H763 AromaticContact CD2-ND1 3.65Å; W759-H763 AromaticContact CE2-CE1 3.36Å; W759-H763 AromaticContact CE2-CG 3.96Å; W759-H763 AromaticContact CE2-ND1 3.49Å; W759-H763 AromaticContact CE2-NE2 3.71Å; W759-H763 AromaticContact CG-ND1 3.89Å; W759-H763 AromaticContact CZ2-CD2 3.76Å; W759-H763 AromaticContact CZ2-CE1 3.81Å; W759-H763 AromaticContact CZ2-CG 3.93Å; W759-H763 AromaticContact CZ2-ND1 3.93Å; W759-H763 AromaticContact CZ2-NE2 3.68Å; W759-H763 AromaticContact NE1-CE1 3.12Å; W759-H763 PolarHBondContact NE1-CE1 2.84Å; W759-H763 AromaticContact NE1-ND1 3.63Å; W759-H763 AromaticContact NE1-NE2 3.68Å; W759-H763 WeakPolarHBondContact O-CB 3.28Å; W759-H763 PolarHBondContact O-N 3.3Å; W759-H763 PolarHBondContact O-ND1 3.29Å; I761-H763 VanDerWaalsContact C-N 3.25Å; I761-H763 PolarHBondContact O-N 3.03Å; H763-Y765 VanDerWaalsContact C-N 3.3Å; H763-Y765 HydrophobicContact CB-CD2 3.73Å; H763-Y765 HydrophobicContact CB-CE2 3.62Å; H763-Y765 PolarHBondContact O-N 3.18Å
764K93.1Very high93.7Very high158 Ų15878.6 Ų78.669%0.68737%0.369SS*.THydrogen-bonded Turntrans6128.4173.1-57179.6-179.2178.70115.3L760 I761 E762 M779L760-K764 PolarHBondContact O-N 2.98Å; I761-K764 PolarHBondContact O-N 2.91Å; E762-K764 VanDerWaalsContact C-N 3.26Å; E762-K764 PolarHBondContact O-N 3.04Å; K764-M779 VanDerWaalsContact C-CE 3.4Å; K764-M779 HydrophobicContact CB-CE 3.54Å; K764-M779 HydrophobicContact CG-CE 4.14Å; K764-M779 VanDerWaalsContact O-CE 3.23Å; K764-M779 WeakPolarHBondContact O-CE 3.3Å
765Y94Very high93.8Very high92 Ų9272.7 Ų72.736%0.36134%0.344SS..SBendtrans-80.4-35.5170.6-68-75.2000112I720 W759 L760 H763 Y778 M779I720-Y765 HydrophobicContact CD1-CD1 4.21Å; I720-Y765 HydrophobicContact CD1-CE1 4.44Å; I720-Y765 HydrophobicContact CD1-CG 4.35Å; W759-Y765 HydrophobicContact CH2-CE2 4.22Å; W759-Y765 HydrophobicContact CZ3-CD2 4.34Å; W759-Y765 AromaticContact CZ3-CE2 3.94Å; W759-Y765 HydrophobicContact CZ3-CE2 3.94Å; L760-Y765 HydrophobicContact CD2-CD2 3.62Å; L760-Y765 HydrophobicContact CD2-CE2 4.35Å; L760-Y765 HydrophobicContact CD2-CG 3.99Å; L760-Y765 PolarHBondContact O-N 3.21Å; H763-Y765 VanDerWaalsContact C-N 3.3Å; H763-Y765 HydrophobicContact CB-CD2 3.73Å; H763-Y765 HydrophobicContact CB-CE2 3.62Å; H763-Y765 PolarHBondContact O-N 3.18Å; Y765-Y778 WeakPolarHBondContact O-CD2 3.25Å; Y765-M779 PolarHBondContact O-N 2.66Å
766I95Very high94Very high0 Ų069.2 Ų69.20%033%0.328CS..EExtended strand (participates in β ladder)trans-137.3159.3179.663.7177.9000109.6M723 I757 L760 I761 I777 Y778M723-I766 HydrophobicContact CB-CG2 4.04Å; M723-I766 HydrophobicContact CE-CB 4.06Å; M723-I766 HydrophobicContact CE-CG2 3.58Å; M723-I766 HydrophobicContact CG-CG2 3.77Å; M723-I766 HydrophobicContact SD-CG2 4.31Å; I757-I766 HydrophobicContact CG2-CD1 4.25Å; L760-I766 HydrophobicContact CB-CD1 3.92Å; L760-I766 HydrophobicContact CB-CG1 3.92Å; L760-I766 PolarHBondContact O-N 3.24Å; I761-I766 WeakPolarHBondContact CA-O 3.29Å; I761-I766 HydrophobicContact CG1-CD1 4.07Å; I761-I766 HydrophobicContact CG1-CG1 3.68Å; I766-I777 CarbonylContact C-O 3.6Å; I766-I777 VanDerWaalsContact CA-O 3.27Å; I766-I777 WeakPolarHBondContact CA-O 3.24Å; I766-Y778 HydrophobicContact CG2-CD2 4.24Å
767R95.1Very high94Very high91 Ų9170 Ų7034%0.34333%0.332SS..EExtended strand (participates in β ladder)trans-132.4161.617064.1177.8-173.5121.5-8.5110.6E770 F776 I777 M779R767-E770 IonicContact CZ-OE1 3.57Å; R767-E770 IonicContact NH1-OE1 2.88Å; R767-E770 PolarHBondContact NH1-OE1 3.47Å; R767-F776 CarbonylContact O-C 3.6Å; R767-F776 WeakPolarHBondContact O-CA 3.2Å; R767-I777 HydrophobicContact CG-CB 3.96Å; R767-I777 PolarHBondContact N-O 3.46Å; R767-I777 PolarHBondContact O-N 3.09Å; R767-M779 HydrophobicContact CB-CE 4.3Å; R767-M779 HydrophobicContact CB-CG 4.04Å; R767-M779 HydrophobicContact CB-SD 3.6Å; R767-M779 VanDerWaalsContact CD-SD 3.6Å; R767-M779 HydrophobicContact CG-CG 3.77Å; R767-M779 HydrophobicContact CG-SD 3.72Å
768R95.3Very high94Very high83 Ų8371.4 Ų71.431%0.31334%0.337SS..EExtended strand (participates in β ladder)trans-76.3145.1167.3-60.3-171.2173.794.71.7109.7E758 I761 I773 T775 F776E758-R768 IonicContact OE1-CZ 3.84Å; E758-R768 IonicContact OE1-NH2 3.84Å; E758-R768 PolarHBondContact OE1-NH2 2.79Å; E758-R768 IonicContact OE2-CZ 3.94Å; E758-R768 IonicContact OE2-NH1 2.65Å; E758-R768 IonicContact OE2-NH2 2.8Å; E758-R768 PolarHBondContact OE2-NH2 3.07Å; I761-R768 HydrophobicContact CD1-CG 4.03Å; R768-I773 VanDerWaalsContact CD-CG1 3.41Å; R768-T775 CarbonylContact C-O 3.5Å; R768-T775 WeakPolarHBondContact CA-O 3.28Å; R768-F776 HydrophobicContact CG-CD1 4.17Å; R768-F776 HydrophobicContact CG-CE1 4.08Å
769D93.3Very high93.9Very high21 Ų2171.9 Ų71.911%0.11234%0.341CS..  trans-64.8142.3170.1-167.3-65.6000109.3K728 S771 T775 I777K728-D769 WeakPolarHBondContact CE-OD2 3.41Å; K728-D769 IonicContact NZ-OD2 3.31Å; K728-D769 PolarHBondContact NZ-OD2 3.31Å; D769-S771 VanDerWaalsContact C-N 3.25Å; D769-S771 PolarHBondContact O-N 3.27Å; D769-S771 WeakPolarHBondContact OD1-CB 3.43Å; D769-S771 PolarHBondContact OD1-N 2.92Å; D769-S771 PolarHBondContact OD1-OG 3.08Å; D769-T775 HydrophobicContact CB-CG2 4.04Å; D769-T775 PolarHBondContact N-O 3.35Å; D769-I777 HydrophobicContact CB-CD1 3.97Å; D769-I777 HydrophobicContact CB-CG1 4.28Å
770E90.8Very high93Very high169 Ų16972.4 Ų72.479%0.7936%0.363SS*.SBendtrans-69.2-26.5-178.9-71.5161-140.600112.2R767R767-E770 IonicContact CZ-OE1 3.57Å; R767-E770 IonicContact NH1-OE1 2.88Å; R767-E770 PolarHBondContact NH1-OE1 3.47Å
771S91.4Very high92.9Very high104 Ų10476 Ų7673%0.72738%0.381SS*.SBendtrans-91.5-26.9179.965.60000113.8D769D769-S771 VanDerWaalsContact C-N 3.25Å; D769-S771 PolarHBondContact O-N 3.27Å; D769-S771 WeakPolarHBondContact OD1-CB 3.43Å; D769-S771 PolarHBondContact OD1-N 2.92Å; D769-S771 PolarHBondContact OD1-OG 3.08Å
772D91.6Very high92.8Very high57 Ų5778.1 Ų78.131%0.30539%0.392SS..  trans-144111.6-178.817525.3000112N774 T775D772-N774 PolarHBondContact O-N 3.21Å; D772-N774 VanDerWaalsContact O-N 3.12Å; D772-N774 WeakPolarHBondContact OD1-CB 3.41Å; D772-N774 PolarHBondContact OD1-N 3.03Å; D772-N774 PolarHBondContact OD1-ND2 3.31Å; D772-T775 PolarHBondContact O-N 3.04Å; D772-T775 PolarHBondContact OD2-N 2.8Å; D772-T775 PolarHBondContact OD2-OG1 3.03Å
773I90.8Very high92.7Very high114 Ų11474.2 Ų74.259%0.58538%0.375SS*.THydrogen-bonded Turntrans-61.2-21.7178.9-157.5175.1000113.1R768 T775R768-I773 VanDerWaalsContact CD-CG1 3.41Å; I773-T775 VanDerWaalsContact C-N 3.29Å
774N92.8Very high92.5Very high94 Ų9473.4 Ų73.450%0.50337%0.373SS..THydrogen-bonded Turntrans-86.1-0.7177.5-60.4-59.1000112.9S730 N731 D772S730-N774 CarbonylContact C-O 3.6Å; S730-N774 WeakPolarHBondContact CA-O 3.38Å; N731-N774 WeakPolarHBondContact CB-O 3.25Å; N731-N774 PolarHBondContact N-O 3.4Å; D772-N774 PolarHBondContact O-N 3.21Å; D772-N774 VanDerWaalsContact O-N 3.12Å; D772-N774 WeakPolarHBondContact OD1-CB 3.41Å; D772-N774 PolarHBondContact OD1-N 3.03Å; D772-N774 PolarHBondContact OD1-ND2 3.31Å
775T94.9Very high92.5Very high17 Ų1768.1 Ų68.110%0.10435%0.353CS..EExtended strand (participates in β ladder)trans-109.8132.2177.6-66.50000110.1K728 R768 D769 D772 I773K728-T775 HydrophobicContact CD-CG2 4.17Å; K728-T775 VanDerWaalsContact CE-CG2 3.47Å; K728-T775 HydrophobicContact CG-CG2 3.61Å; R768-T775 CarbonylContact C-O 3.5Å; R768-T775 WeakPolarHBondContact CA-O 3.28Å; D769-T775 HydrophobicContact CB-CG2 4.04Å; D769-T775 PolarHBondContact N-O 3.35Å; D772-T775 PolarHBondContact O-N 3.04Å; D772-T775 PolarHBondContact OD2-N 2.8Å; D772-T775 PolarHBondContact OD2-OG1 3.03Å; I773-T775 VanDerWaalsContact C-N 3.29Å
776F96.2Very high92.4Very high5 Ų566.5 Ų66.52%0.02235%0.353CS..EExtended strand (participates in β ladder)trans-107.3142.6178.3-55.4-63.6000110.7M723 K728 I729 N731 L734 I757 I761 R767 R768M723-F776 HydrophobicContact CE-CB 3.65Å; M723-F776 HydrophobicContact SD-CB 4.01Å; K728-F776 VanDerWaalsContact CA-O 3.31Å; K728-F776 WeakPolarHBondContact CA-O 3.27Å; I729-F776 PolarHBondContact N-O 3.15Å; I729-F776 PolarHBondContact O-N 2.93Å; N731-F776 HydrophobicContact CB-CE2 3.82Å; N731-F776 HydrophobicContact CB-CZ 4.36Å; N731-F776 VanDerWaalsContact ND2-CE2 3.32Å; N731-F776 WeakPolarHBondContact ND2-CE2 3.48Å; N731-F776 WeakPolarHBondContact ND2-CZ 3.37Å; L734-F776 HydrophobicContact CD2-CD2 3.75Å; L734-F776 HydrophobicContact CD2-CE2 3.94Å; I757-F776 HydrophobicContact CD1-CE2 4.11Å; I757-F776 HydrophobicContact CD1-CZ 4.27Å; I757-F776 HydrophobicContact CG2-CD1 4.47Å; I757-F776 HydrophobicContact CG2-CE1 3.73Å; I757-F776 HydrophobicContact CG2-CE2 4.28Å; I757-F776 HydrophobicContact CG2-CZ 3.62Å; I761-F776 HydrophobicContact CD1-CD1 4.48Å; I761-F776 HydrophobicContact CD1-CE1 4.16Å; R767-F776 CarbonylContact O-C 3.6Å; R767-F776 WeakPolarHBondContact O-CA 3.2Å; R768-F776 HydrophobicContact CG-CD1 4.17Å; R768-F776 HydrophobicContact CG-CE1 4.08Å
777I94.9Very high92.2Very high31 Ų3171.3 Ų71.316%0.15938%0.378CS..EExtended strand (participates in β ladder)trans-119.7133.3176.9-57.4170.7000108.7M723 K727 K728 I766 R767 D769M723-I777 VanDerWaalsContact CE-C 3.43Å; K727-I777 WeakPolarHBondContact O-CA 3.19Å; K728-I777 HydrophobicContact CG-CG1 4.37Å; I766-I777 CarbonylContact C-O 3.6Å; I766-I777 VanDerWaalsContact CA-O 3.27Å; I766-I777 WeakPolarHBondContact CA-O 3.24Å; R767-I777 HydrophobicContact CG-CB 3.96Å; R767-I777 PolarHBondContact N-O 3.46Å; R767-I777 PolarHBondContact O-N 3.09Å; D769-I777 HydrophobicContact CB-CD1 3.97Å; D769-I777 HydrophobicContact CB-CG1 4.28Å
778Y95.8Very high92Very high33 Ų3369.8 Ų69.813%0.12938%0.381CS..EExtended strand (participates in β ladder)trans-75.3134.6175.6-172.9-121.1000110.9I720 M723 K724 K727 Y765 I766 A780I720-Y778 HydrophobicContact CG2-CE2 4.42Å; M723-Y778 HydrophobicContact CB-CD2 3.73Å; M723-Y778 HydrophobicContact CB-CE2 4.49Å; M723-Y778 HydrophobicContact CB-CG 4.25Å; M723-Y778 WeakPolarHBondContact O-CB 3.49Å; K724-Y778 HydrophobicContact CB-CD1 4.48Å; K724-Y778 HydrophobicContact CB-CE1 3.89Å; K724-Y778 HydrophobicContact CB-CE2 4.36Å; K724-Y778 HydrophobicContact CG-CE1 3.88Å; K727-Y778 HydrophobicContact CD-CD1 4.01Å; K727-Y778 PolarHBondContact O-N 3.32Å; Y765-Y778 WeakPolarHBondContact O-CD2 3.25Å; I766-Y778 HydrophobicContact CG2-CD2 4.24Å; Y778-A780 WeakPolarHBondContact CD1-OXT 3.38Å; Y778-A780 HydrophobicContact CE1-CB 4.14Å; Y778-A780 WeakPolarHBondContact CE1-OXT 3.23Å; Y778-A780 HydrophobicContact CE2-CB 4.26Å
779M90.8Very high91.7Very high83 Ų8368.7 Ų68.741%0.40939%0.387SS..  trans-105.9-13.3-174.1-66.6-151.9-61.700115.4K764 Y765 R767K764-M779 VanDerWaalsContact C-CE 3.4Å; K764-M779 HydrophobicContact CB-CE 3.54Å; K764-M779 HydrophobicContact CG-CE 4.14Å; K764-M779 VanDerWaalsContact O-CE 3.23Å; K764-M779 WeakPolarHBondContact O-CE 3.3Å; Y765-M779 PolarHBondContact O-N 2.66Å; R767-M779 HydrophobicContact CB-CE 4.3Å; R767-M779 HydrophobicContact CB-CG 4.04Å; R767-M779 HydrophobicContact CB-SD 3.6Å; R767-M779 VanDerWaalsContact CD-SD 3.6Å; R767-M779 HydrophobicContact CG-CG 3.77Å; R767-M779 HydrophobicContact CG-SD 3.72Å
780A77.5Confident91.6Very high96 Ų9673 Ų7379%0.79341%0.411SS*.  trans-100.10176.300000112.1Y778Y778-A780 WeakPolarHBondContact CD1-OXT 3.38Å; Y778-A780 HydrophobicContact CE1-CB 4.14Å; Y778-A780 WeakPolarHBondContact CE1-OXT 3.23Å; Y778-A780 HydrophobicContact CE2-CB 4.26Å

Retrieved 780 of 780 residues in 174.1 ms (Link to these results)