A0A096NBF5_PAPAN Loading...

V-type proton ATPase subunit H

Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit H is essential for V-ATPase activity, but not for the assembly of the complex. Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes.

AlphaFold DB (A0A2K5V7B1), UniProt , Accession A0A096NBF5, Species PAPAN (Papio anubis, Olive baboon), Gene ATP6V1H, Length 483 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	28.7	Very low	31.6	Very low	250 Å²	250	136.3 Å²	136.3	100%	1.232	73%	0.728	S	S	*	*				0	73	0	-82.5	170.3	141.2	0	0	108.9
2	T	25.6	Very low	31.3	Very low	136 Å²	136	132.9 Å²	132.9	83%	0.834	73%	0.733	S	S	*	*			trans	-89.8	118.3	176.5	9.8	0	0	0	0	107.5	M4	T2-M4 VanDerWaalsContact C-N 3.25Å; T2-M4 PolarHBondContact O-N 3.33Å
3	K	27.6	Very low	31.1	Very low	213 Å²	213	129.8 Å²	129.8	93%	0.926	74%	0.736	S	S	*	*			trans	-63.5	91.6	165.6	-89.2	179.3	172.7	174.4	0	107	D5	K3-D5 PolarHBondContact O-N 3.04Å
4	M	30.1	Very low	31.4	Very low	160 Å²	160	129.1 Å²	129.1	79%	0.788	74%	0.735	S	S	*	*			trans	-67.6	116.3	169.4	-123.9	173.1	167.6	0	0	107.2	T2 I6	T2-M4 VanDerWaalsContact C-N 3.25Å; T2-M4 PolarHBondContact O-N 3.33Å; M4-I6 PolarHBondContact O-N 3.23Å; M4-I6 VanDerWaalsContact O-N 3.14Å
5	D	32.7	Very low	31.8	Very low	106 Å²	106	128.5 Å²	128.5	57%	0.567	74%	0.738	S	S	*	*			trans	-77.3	99.2	-172.6	-158	7.7	0	0	0	109.8	K3 R7	K3-D5 PolarHBondContact O-N 3.04Å; D5-R7 PolarHBondContact O-N 3.39Å; D5-R7 WeakPolarHBondContact OD1-CB 3.35Å; D5-R7 WeakPolarHBondContact OD1-CD 3.4Å; D5-R7 WeakPolarHBondContact OD1-CG 2.98Å; D5-R7 IonicContact OD1-CZ 3.08Å; D5-R7 IonicContact OD1-NE 3.59Å; D5-R7 PolarHBondContact OD1-NE 3.42Å; D5-R7 IonicContact OD2-NE 3.55Å
6	I	36.3	Very low	32.7	Very low	76 Å²	76	126.4 Å²	126.4	39%	0.39	73%	0.729	S	S	.	*	G	3₁₀ helix	trans	-64.6	1.2	177.4	-49.3	175.2	0	0	0	111.4	M4	M4-I6 PolarHBondContact O-N 3.23Å; M4-I6 VanDerWaalsContact O-N 3.14Å
7	R	35	Very low	34.7	Very low	202 Å²	202	121.8 Å²	121.8	76%	0.762	70%	0.701	S	S	*	*	G	3₁₀ helix	trans	-79.9	-19.3	-173.8	-65.9	176.4	-136.6	-158.1	-4	114.3	D5	D5-R7 PolarHBondContact O-N 3.39Å; D5-R7 WeakPolarHBondContact OD1-CB 3.35Å; D5-R7 WeakPolarHBondContact OD1-CD 3.4Å; D5-R7 WeakPolarHBondContact OD1-CG 2.98Å; D5-R7 IonicContact OD1-CZ 3.08Å; D5-R7 IonicContact OD1-NE 3.59Å; D5-R7 PolarHBondContact OD1-NE 3.42Å; D5-R7 IonicContact OD2-NE 3.55Å
8	G	27.8	Very low	36.9	Very low	72 Å²	72	117.6 Å²	117.6	74%	0.742	68%	0.675	S	S	*	*	G	3₁₀ helix	trans	-83.5	-10.4	-170.7	0	0	0	0	0	117.2	V10	G8-V10 PolarHBondContact O-N 2.98Å
9	A	30.2	Very low	39.3	Very low	68 Å²	68	111.6 Å²	111.6	56%	0.562	64%	0.641	S	S	*	*	S	Bend	trans	-93.7	18	-167.8	0	0	0	0	0	115.6
10	V	36.8	Very low	41.4	Very low	70 Å²	70	108.7 Å²	108.7	42%	0.424	63%	0.631	S	S	.	*	S	Bend	trans	-112.4	-19.5	-169.1	-164.7	0	0	0	0	114.6	G8	G8-V10 PolarHBondContact O-N 2.98Å
11	D	37.2	Very low	43.4	Very low	146 Å²	146	106.1 Å²	106.1	78%	0.781	62%	0.622	S	S	*	*			trans	-116	91.1	-168.7	-69.6	-33	0	0	0	112.2
12	A	27.3	Very low	46.2	Very low	96 Å²	96	97.3 Å²	97.3	79%	0.793	58%	0.577	S	S	*	*	S	Bend	trans	180	106.8	142.7	0	0	0	0	0	110.3
13	A	29.3	Very low	49.1	Very low	93 Å²	93	91.2 Å²	91.2	77%	0.769	54%	0.54	S	S	*	.			trans	35.2	117.4	151.6	0	0	0	0	0	120.1
14	V	35	Very low	52	Low	119 Å²	119	83.2 Å²	83.2	72%	0.721	51%	0.514	S	S	*	.				-149.9	124.6	109.2	-179.5	0	0	0	0	109.6	T16	V14-T16 PolarHBondContact O-N 2.96Å; V14-T16 VanDerWaalsContact O-N 3.15Å
15	P	37.9	Very low	54.8	Low	121 Å²	121	81.7 Å²	81.7	79%	0.786	51%	0.505	S	S	*	.			trans	-75.7	97.6	172.7	32	-32.9	0	0	0	110.3
16	T	45.7	Very low	57.5	Low	95 Å²	95	77 Å²	77	58%	0.583	48%	0.48	S	S	*	.			trans	-136.5	7.4	163.2	11.8	0	0	0	0	112.2	V14 I18	V14-T16 PolarHBondContact O-N 2.96Å; V14-T16 VanDerWaalsContact O-N 3.15Å; T16-I18 PolarHBondContact O-N 2.94Å
17	N	66.4	Low	60	Low	48 Å²	48	79.6 Å²	79.6	26%	0.257	49%	0.485	S	S	.	.			trans	-88.3	108.5	-176.7	-163.6	-11.2	0	0	0	109.3	I19 A20 A21	N17-I19 PolarHBondContact O-N 3.48Å; N17-I19 PolarHBondContact OD1-N 3.09Å; N17-A20 HydrophobicContact CB-CB 4.32Å; N17-A20 WeakPolarHBondContact O-CB 3.44Å; N17-A20 PolarHBondContact O-N 3.27Å; N17-A21 PolarHBondContact O-N 3.11Å
18	I	74.9	Confident	62.4	Low	46 Å²	46	73.8 Å²	73.8	24%	0.236	48%	0.48	C	S	.	.	H	α-helix	trans	-52.3	-30.2	176.9	-81.8	85	0	0	0	111.8	T16 A20 A21 K22 Q196 Y197	T16-I18 PolarHBondContact O-N 2.94Å; I18-A20 VanDerWaalsContact C-N 3.34Å; I18-A20 PolarHBondContact O-N 3.14Å; I18-A21 PolarHBondContact O-N 3.34Å; I18-K22 HydrophobicContact CG2-CD 4.02Å; I18-K22 HydrophobicContact CG2-CG 4.11Å; I18-K22 WeakPolarHBondContact O-CB 3.43Å; I18-K22 WeakPolarHBondContact O-CG 3.37Å; I18-K22 PolarHBondContact O-N 3.1Å; I18-Q196 HydrophobicContact CB-CB 4.38Å; I18-Q196 HydrophobicContact CD1-CB 3.71Å; I18-Q196 VanDerWaalsContact CD1-CD 3.42Å; I18-Q196 HydrophobicContact CD1-CG 3.45Å; I18-Q196 VanDerWaalsContact CD1-CG 3.45Å; I18-Q196 HydrophobicContact CG1-CB 4.23Å; I18-Q196 HydrophobicContact CG1-CG 4.21Å; I18-Q196 VanDerWaalsContact CG1-OE1 3.24Å; I18-Y197 HydrophobicContact CG2-CE1 4.46Å
19	I	81.9	Confident	65.2	Low	4 Å²	4	74 Å²	74	2%	0.021	46%	0.464	C	S	.	.	H	α-helix	trans	-61.8	-42.1	174.1	-62	-171.1	0	0	0	111.5	N17 A23 F136 M140 Y197 C200	N17-I19 PolarHBondContact O-N 3.48Å; N17-I19 PolarHBondContact OD1-N 3.09Å; I19-A23 WeakPolarHBondContact O-CB 3.47Å; I19-A23 PolarHBondContact O-N 2.66Å; I19-F136 HydrophobicContact CG2-CE2 4.11Å; I19-M140 HydrophobicContact CG2-CE 3.69Å; I19-Y197 HydrophobicContact CD1-CD1 3.84Å; I19-Y197 HydrophobicContact CD1-CE1 4.34Å; I19-Y197 HydrophobicContact CG1-CD1 3.61Å; I19-Y197 HydrophobicContact CG1-CE1 3.73Å; I19-C200 HydrophobicContact CD1-CB 3.29Å; I19-C200 WeakPolarHBondContact CD1-SG 3.33Å; I19-C200 HydrophobicContact CG1-CB 4.41Å
20	A	82.1	Confident	67.8	Low	53 Å²	53	80.6 Å²	80.6	44%	0.438	48%	0.48	S	S	.	.	H	α-helix	trans	-67.8	-38.9	179.7	0	0	0	0	0	111.5	N17 I18 A23 A24	N17-A20 HydrophobicContact CB-CB 4.32Å; N17-A20 WeakPolarHBondContact O-CB 3.44Å; N17-A20 PolarHBondContact O-N 3.27Å; I18-A20 VanDerWaalsContact C-N 3.34Å; I18-A20 PolarHBondContact O-N 3.14Å; A20-A23 PolarHBondContact O-N 3.35Å; A20-A24 PolarHBondContact O-N 2.71Å; A20-A24 VanDerWaalsContact O-N 3.1Å
21	A	83.8	Confident	70.3	Confident	55 Å²	55	78.3 Å²	78.3	46%	0.455	47%	0.466	S	S	.	.	H	α-helix	trans	-64.3	-51.1	174.7	0	0	0	0	0	111.4	N17 I18 A23 A24 E25	N17-A21 PolarHBondContact O-N 3.11Å; I18-A21 PolarHBondContact O-N 3.34Å; A21-A23 VanDerWaalsContact C-N 3.3Å; A21-A23 PolarHBondContact O-N 3.49Å; A21-A24 WeakPolarHBondContact O-CB 3.43Å; A21-A24 PolarHBondContact O-N 3.12Å; A21-E25 PolarHBondContact O-N 2.98Å; A21-E25 VanDerWaalsContact O-N 3.1Å
22	K	86.4	Confident	72.9	Confident	65 Å²	65	76.3 Å²	76.3	28%	0.283	46%	0.455	S	S	.	.	H	α-helix	trans	-61.3	-37.1	175.8	-74.9	-168.9	175.8	-162.6	0	112.5	I18 A24 E25 V26 F136 Y197	I18-K22 HydrophobicContact CG2-CD 4.02Å; I18-K22 HydrophobicContact CG2-CG 4.11Å; I18-K22 WeakPolarHBondContact O-CB 3.43Å; I18-K22 WeakPolarHBondContact O-CG 3.37Å; I18-K22 PolarHBondContact O-N 3.1Å; K22-A24 VanDerWaalsContact C-N 3.27Å; K22-A24 PolarHBondContact O-N 3.49Å; K22-E25 PolarHBondContact O-N 3.21Å; K22-V26 WeakPolarHBondContact O-CB 3.2Å; K22-V26 VanDerWaalsContact O-CG2 3.23Å; K22-V26 WeakPolarHBondContact O-CG2 3.33Å; K22-V26 PolarHBondContact O-N 3.2Å; K22-F136 HydrophobicContact CB-CD2 3.49Å; K22-F136 VanDerWaalsContact CB-CD2 3.49Å; K22-F136 HydrophobicContact CB-CE2 3.54Å; K22-F136 HydrophobicContact CB-CG 4.48Å; K22-F136 HydrophobicContact CD-CB 4.39Å; K22-F136 HydrophobicContact CD-CD2 3.99Å; K22-F136 HydrophobicContact CG-CD2 4.39Å; K22-Y197 WeakPolarHBondContact CD-OH 3.47Å; K22-Y197 VanDerWaalsContact CE-OH 3.3Å; K22-Y197 WeakPolarHBondContact CE-OH 3.41Å; K22-Y197 PolarHBondContact NZ-OH 3.22Å
23	A	87.6	Confident	76	Confident	8 Å²	8	72 Å²	72	7%	0.066	42%	0.419	C	S	.	.	H	α-helix	trans	-63.1	-35.3	174.7	0	0	0	0	0	111.6	I19 A20 A21 R27 T95 F136 M140	I19-A23 WeakPolarHBondContact O-CB 3.47Å; I19-A23 PolarHBondContact O-N 2.66Å; A20-A23 PolarHBondContact O-N 3.35Å; A21-A23 VanDerWaalsContact C-N 3.3Å; A21-A23 PolarHBondContact O-N 3.49Å; A23-R27 WeakPolarHBondContact O-CB 3.27Å; A23-R27 VanDerWaalsContact O-CG 3.28Å; A23-R27 WeakPolarHBondContact O-CG 3.41Å; A23-R27 PolarHBondContact O-N 2.73Å; A23-R27 PolarHBondContact O-NE 3.14Å; A23-T95 HydrophobicContact CB-CG2 4.02Å; A23-F136 HydrophobicContact CB-CE2 4.21Å; A23-F136 HydrophobicContact CB-CZ 4.05Å; A23-M140 HydrophobicContact CB-CE 4.16Å
24	A	88	Confident	79	Confident	44 Å²	44	71.5 Å²	71.5	36%	0.364	40%	0.4	S	S	.	.	H	α-helix	trans	-67.2	-40.7	173.9	0	0	0	0	0	112.4	A20 A21 K22 R27 A28	A20-A24 PolarHBondContact O-N 2.71Å; A20-A24 VanDerWaalsContact O-N 3.1Å; A21-A24 WeakPolarHBondContact O-CB 3.43Å; A21-A24 PolarHBondContact O-N 3.12Å; K22-A24 VanDerWaalsContact C-N 3.27Å; K22-A24 PolarHBondContact O-N 3.49Å; A24-R27 PolarHBondContact O-N 3.08Å; A24-A28 PolarHBondContact O-N 2.87Å
25	E	88.7	Confident	81.7	Confident	128 Å²	128	68.3 Å²	68.3	60%	0.598	38%	0.383	S	S	*	.	H	α-helix	trans	-63.7	-46.1	173.9	-66.6	173.1	-174.4	0	0	111.6	A21 K22 R27 A28	A21-E25 PolarHBondContact O-N 2.98Å; A21-E25 VanDerWaalsContact O-N 3.1Å; K22-E25 PolarHBondContact O-N 3.21Å; E25-R27 VanDerWaalsContact C-N 3.3Å; E25-R27 PolarHBondContact O-N 2.97Å; E25-A28 WeakPolarHBondContact O-CB 3.23Å; E25-A28 PolarHBondContact O-N 3.47Å; E25-A28 VanDerWaalsContact O-N 3.08Å
26	V	89.9	Confident	84.2	Confident	8 Å²	8	63.9 Å²	63.9	5%	0.048	35%	0.351	C	S	.	.	H	α-helix	trans	-60.3	-41.7	177.2	170.2	0	0	0	0	110.6	K22 A28 N29 Q91 Y92 F136	K22-V26 WeakPolarHBondContact O-CB 3.2Å; K22-V26 VanDerWaalsContact O-CG2 3.23Å; K22-V26 WeakPolarHBondContact O-CG2 3.33Å; K22-V26 PolarHBondContact O-N 3.2Å; V26-A28 PolarHBondContact O-N 3.18Å; V26-N29 WeakPolarHBondContact O-CB 3.41Å; V26-N29 PolarHBondContact O-N 3.45Å; V26-Q91 HydrophobicContact CG1-CB 4.13Å; V26-Q91 HydrophobicContact CG2-CB 4.14Å; V26-Y92 VanDerWaalsContact CG1-CA 3.46Å; V26-Y92 HydrophobicContact CG1-CD2 4.13Å; V26-Y92 WeakPolarHBondContact O-CD2 3.33Å; V26-F136 HydrophobicContact CG2-CE1 4.04Å; V26-F136 HydrophobicContact CG2-CZ 4.18Å
27	R	87.6	Confident	86.4	Confident	131 Å²	131	61.6 Å²	61.6	49%	0.494	34%	0.335	S	S	.	.	H	α-helix	trans	-60.4	-28	175.6	-82.4	-177.4	-82.2	127.3	-8	113.8	A23 A24 E25 N29 T95	A23-R27 WeakPolarHBondContact O-CB 3.27Å; A23-R27 VanDerWaalsContact O-CG 3.28Å; A23-R27 WeakPolarHBondContact O-CG 3.41Å; A23-R27 PolarHBondContact O-N 2.73Å; A23-R27 PolarHBondContact O-NE 3.14Å; A24-R27 PolarHBondContact O-N 3.08Å; E25-R27 VanDerWaalsContact C-N 3.3Å; E25-R27 PolarHBondContact O-N 2.97Å; R27-N29 VanDerWaalsContact C-N 3.27Å; R27-N29 PolarHBondContact O-N 3.33Å; R27-T95 HydrophobicContact CG-CG2 3.95Å
28	A	86.9	Confident	87.6	Confident	79 Å²	79	66.6 Å²	66.6	65%	0.653	36%	0.357	S	S	*	.	H	α-helix	trans	-75	-18.3	177.9	0	0	0	0	0	112.9	A24 E25 V26	A24-A28 PolarHBondContact O-N 2.87Å; E25-A28 WeakPolarHBondContact O-CB 3.23Å; E25-A28 PolarHBondContact O-N 3.47Å; E25-A28 VanDerWaalsContact O-N 3.08Å; V26-A28 PolarHBondContact O-N 3.18Å
29	N	86.6	Confident	88.4	Confident	76 Å²	76	66.6 Å²	66.6	41%	0.406	37%	0.368	S	S	.	.	P	Polyproline II helix	trans	-76.2	131.7	179.4	-66.3	-32.8	0	0	0	111.1	V26 R27 Y92	V26-N29 WeakPolarHBondContact O-CB 3.41Å; V26-N29 PolarHBondContact O-N 3.45Å; R27-N29 VanDerWaalsContact C-N 3.27Å; R27-N29 PolarHBondContact O-N 3.33Å; N29-Y92 WeakPolarHBondContact O-CE2 3.45Å
30	K	83.7	Confident	88.7	Confident	207 Å²	207	74.9 Å²	74.9	90%	0.9	41%	0.407	S	S	*	.	P	Polyproline II helix	trans	-92.6	123	171.8	-69.4	-172.4	178.9	-177.7	0	110.3
31	V	89.8	Confident	89	Confident	22 Å²	22	76.3 Å²	76.3	13%	0.133	41%	0.405	C	S	.	.	P	Polyproline II helix	trans	-88.4	129.3	175.3	-176	0	0	0	0	109.6	W33 Y36 T89 Y92	V31-W33 HydrophobicContact CB-CD2 4.28Å; V31-W33 HydrophobicContact CB-CH2 4.34Å; V31-W33 HydrophobicContact CB-CZ2 3.8Å; V31-W33 HydrophobicContact CG1-CD2 3.77Å; V31-W33 HydrophobicContact CG1-CE3 3.85Å; V31-W33 HydrophobicContact CG1-CG 4.45Å; V31-W33 HydrophobicContact CG1-CH2 3.88Å; V31-W33 HydrophobicContact CG1-CZ2 3.79Å; V31-W33 HydrophobicContact CG1-CZ3 3.9Å; V31-W33 HydrophobicContact CG2-CZ2 4.2Å; V31-W33 PolarHBondContact O-N 3.41Å; V31-Y36 HydrophobicContact CG1-CD2 4.37Å; V31-Y36 HydrophobicContact CG1-CE2 3.78Å; V31-T89 HydrophobicContact CG1-CG2 3.83Å; V31-Y92 HydrophobicContact CG2-CD1 3.57Å; V31-Y92 HydrophobicContact CG2-CD2 4.31Å; V31-Y92 HydrophobicContact CG2-CE1 4.13Å; V31-Y92 HydrophobicContact CG2-CG 3.7Å
32	N	91.6	Very high	89.4	Confident	105 Å²	105	74.4 Å²	74.4	56%	0.561	39%	0.387	S	S	*	.			trans	-87.7	82.5	174.1	-176	-0.8	0	0	0	110.5	Q34 S35	N32-Q34 PolarHBondContact O-N 3.4Å; N32-Q34 WeakPolarHBondContact OD1-CB 3.08Å; N32-Q34 PolarHBondContact OD1-N 3.49Å; N32-S35 PolarHBondContact O-N 2.93Å; N32-S35 VanDerWaalsContact O-N 3.14Å; N32-S35 PolarHBondContact O-OG 3.14Å; N32-S35 PolarHBondContact OD1-N 3.32Å
33	W	92.6	Very high	89.7	Confident	6 Å²	6	73.5 Å²	73.5	2%	0.023	39%	0.389	C	S	.	.	H	α-helix	trans	-57	-32	-179.8	-58.5	112.8	0	0	0	113.6	V31 S35 Y36 L37 I42 I50 Q51 E54 L80 I84 T89 Y92 I93 M96	V31-W33 HydrophobicContact CB-CD2 4.28Å; V31-W33 HydrophobicContact CB-CH2 4.34Å; V31-W33 HydrophobicContact CB-CZ2 3.8Å; V31-W33 HydrophobicContact CG1-CD2 3.77Å; V31-W33 HydrophobicContact CG1-CE3 3.85Å; V31-W33 HydrophobicContact CG1-CG 4.45Å; V31-W33 HydrophobicContact CG1-CH2 3.88Å; V31-W33 HydrophobicContact CG1-CZ2 3.79Å; V31-W33 HydrophobicContact CG1-CZ3 3.9Å; V31-W33 HydrophobicContact CG2-CZ2 4.2Å; V31-W33 PolarHBondContact O-N 3.41Å; W33-S35 VanDerWaalsContact C-N 3.25Å; W33-S35 PolarHBondContact O-N 2.89Å; W33-Y36 HydrophobicContact CE3-CD2 4.21Å; W33-Y36 PolarHBondContact O-N 3.49Å; W33-Y36 VanDerWaalsContact O-N 3.09Å; W33-L37 PolarHBondContact O-N 3.02Å; W33-L37 VanDerWaalsContact O-N 3.1Å; W33-I42 HydrophobicContact CE3-CD1 4.44Å; W33-I50 HydrophobicContact CB-CG2 4.31Å; W33-I50 HydrophobicContact CD2-CG1 4.33Å; W33-I50 HydrophobicContact CD2-CG2 3.63Å; W33-I50 HydrophobicContact CE3-CG2 4.1Å; W33-I50 HydrophobicContact CG-CG2 3.71Å; W33-I50 HydrophobicContact CH2-CG1 4.14Å; W33-I50 HydrophobicContact CZ2-CG1 3.67Å; W33-I50 HydrophobicContact CZ2-CG2 4.5Å; W33-Q51 HydrophobicContact CB-CG 4.44Å; W33-E54 WeakPolarHBondContact CZ2-OE1 3.11Å; W33-E54 PolarHBondContact NE1-OE1 3.24Å; W33-E54 PolarHBondContact NE1-OE2 3.22Å; W33-L80 HydrophobicContact CE3-CD2 4.49Å; W33-L80 HydrophobicContact CH2-CD1 4.17Å; W33-L80 HydrophobicContact CZ3-CD1 4Å; W33-L80 HydrophobicContact CZ3-CD2 4.08Å; W33-I84 HydrophobicContact CZ3-CD1 4.12Å; W33-T89 HydrophobicContact CH2-CG2 3.98Å; W33-T89 HydrophobicContact CZ3-CG2 3.87Å; W33-Y92 HydrophobicContact CH2-CD1 4.49Å; W33-Y92 HydrophobicContact CZ2-CD1 4.02Å; W33-Y92 HydrophobicContact CZ2-CE1 4.09Å; W33-I93 HydrophobicContact CH2-CD1 4.26Å; W33-I93 HydrophobicContact CH2-CG1 3.88Å; W33-I93 HydrophobicContact CZ3-CD1 4.48Å; W33-M96 HydrophobicContact CH2-CE 4.36Å; W33-M96 HydrophobicContact CZ2-CE 4.09Å
34	Q	91.6	Very high	89.9	Confident	82 Å²	82	76.2 Å²	76.2	38%	0.383	41%	0.412	S	S	.	.	H	α-helix	trans	-61.8	-34.3	179.5	-164.2	63.9	23.5	0	0	112.5	N32 Y36 L37 Q38	N32-Q34 PolarHBondContact O-N 3.4Å; N32-Q34 WeakPolarHBondContact OD1-CB 3.08Å; N32-Q34 PolarHBondContact OD1-N 3.49Å; Q34-Y36 VanDerWaalsContact C-N 3.32Å; Q34-Y36 PolarHBondContact O-N 3.31Å; Q34-L37 PolarHBondContact O-N 3.08Å; Q34-Q38 WeakPolarHBondContact O-CG 3.47Å; Q34-Q38 PolarHBondContact O-N 3.31Å
35	S	91.6	Very high	90.1	Very high	51 Å²	51	78.8 Å²	78.8	36%	0.357	42%	0.416	S	S	.	.	H	α-helix	trans	-65.5	-36.1	176.9	68.3	0	0	0	0	112.4	N32 W33 G39	N32-S35 PolarHBondContact O-N 2.93Å; N32-S35 VanDerWaalsContact O-N 3.14Å; N32-S35 PolarHBondContact O-OG 3.14Å; N32-S35 PolarHBondContact OD1-N 3.32Å; W33-S35 VanDerWaalsContact C-N 3.25Å; W33-S35 PolarHBondContact O-N 2.89Å; S35-G39 PolarHBondContact O-N 3.13Å
36	Y	91.9	Very high	90.3	Very high	29 Å²	29	72.9 Å²	72.9	11%	0.114	39%	0.389	C	S	.	.	H	α-helix	trans	-72.5	-34.9	176	-66.5	-64.2	0	0	0	112.4	V31 W33 Q34 G39 Q40 M41 I84 K86 T89	V31-Y36 HydrophobicContact CG1-CD2 4.37Å; V31-Y36 HydrophobicContact CG1-CE2 3.78Å; W33-Y36 HydrophobicContact CE3-CD2 4.21Å; W33-Y36 PolarHBondContact O-N 3.49Å; W33-Y36 VanDerWaalsContact O-N 3.09Å; Q34-Y36 VanDerWaalsContact C-N 3.32Å; Q34-Y36 PolarHBondContact O-N 3.31Å; Y36-G39 CarbonylContact O-C 3.55Å; Y36-G39 PolarHBondContact O-N 2.71Å; Y36-Q40 PolarHBondContact O-N 3.32Å; Y36-M41 HydrophobicContact CD1-CB 4.33Å; Y36-M41 HydrophobicContact CD1-CG 4.5Å; Y36-M41 PolarHBondContact O-N 2.89Å; Y36-I84 HydrophobicContact CD2-CD1 4.42Å; Y36-I84 HydrophobicContact CE1-CG2 4.08Å; Y36-I84 HydrophobicContact CG-CD1 4.39Å; Y36-K86 WeakPolarHBondContact OH-CB 2.96Å; Y36-K86 WeakPolarHBondContact OH-CD 3.24Å; Y36-T89 HydrophobicContact CE2-CG2 3.9Å; Y36-T89 WeakPolarHBondContact OH-CB 3.46Å; Y36-T89 PolarHBondContact OH-OG1 3.36Å
37	L	91.1	Very high	90.5	Very high	47 Å²	47	72.7 Å²	72.7	25%	0.246	39%	0.388	C	S	.	.	H	α-helix	trans	-65.8	-46.7	174.1	179.4	61.5	0	0	0	111.2	W33 Q34 G39 Q40 I42 A44 C47	W33-L37 PolarHBondContact O-N 3.02Å; W33-L37 VanDerWaalsContact O-N 3.1Å; Q34-L37 PolarHBondContact O-N 3.08Å; L37-G39 VanDerWaalsContact C-N 3.26Å; L37-G39 PolarHBondContact O-N 3.24Å; L37-Q40 PolarHBondContact O-N 3.17Å; L37-I42 HydrophobicContact CB-CD1 4.49Å; L37-I42 HydrophobicContact CB-CG1 4.2Å; L37-A44 HydrophobicContact CD1-CB 4.13Å; L37-C47 HydrophobicContact CB-CB 4.34Å; L37-C47 HydrophobicContact CD1-CB 4.45Å; L37-C47 HydrophobicContact CD2-CB 4.16Å
38	Q	92.3	Very high	90.8	Very high	152 Å²	152	72 Å²	72	71%	0.71	39%	0.39	S	S	*	.	H	α-helix	trans	-62.2	-35.9	175.6	-72.7	174.7	-9.8	0	0	112	Q34 Q40	Q34-Q38 WeakPolarHBondContact O-CG 3.47Å; Q34-Q38 PolarHBondContact O-N 3.31Å; Q38-Q40 PolarHBondContact O-N 2.72Å
39	G	89.6	Confident	91.1	Very high	47 Å²	47	68.3 Å²	68.3	49%	0.485	36%	0.359	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76.5	4.2	173.9	0	0	0	0	0	115.1	S35 Y36 L37 M41	S35-G39 PolarHBondContact O-N 3.13Å; Y36-G39 CarbonylContact O-C 3.55Å; Y36-G39 PolarHBondContact O-N 2.71Å; L37-G39 VanDerWaalsContact C-N 3.26Å; L37-G39 PolarHBondContact O-N 3.24Å; G39-M41 PolarHBondContact O-N 3.44Å; G39-M41 VanDerWaalsContact O-N 3.11Å
40	Q	88.6	Confident	91.4	Very high	178 Å²	178	64.7 Å²	64.7	83%	0.832	34%	0.34	S	S	*	.	T	Hydrogen-bonded Turn	trans	56.3	22.4	-177.8	-58.2	-177.4	-15.6	0	0	114.6	Y36 L37 Q38	Y36-Q40 PolarHBondContact O-N 3.32Å; L37-Q40 PolarHBondContact O-N 3.17Å; Q38-Q40 PolarHBondContact O-N 2.72Å
41	M	88	Confident	91.9	Very high	82 Å²	82	58 Å²	58	40%	0.404	31%	0.312	S	S	.	.	S	Bend	trans	-82.7	-21.9	178.9	-61.9	-60	-61.9	0	0	112.3	Y36 G39 H83	Y36-M41 HydrophobicContact CD1-CB 4.33Å; Y36-M41 HydrophobicContact CD1-CG 4.5Å; Y36-M41 PolarHBondContact O-N 2.89Å; G39-M41 PolarHBondContact O-N 3.44Å; G39-M41 VanDerWaalsContact O-N 3.11Å; M41-H83 WeakPolarHBondContact CE-O 3.22Å; M41-H83 WeakPolarHBondContact O-CB 3.03Å
42	I	92.3	Very high	92	Very high	15 Å²	15	61.1 Å²	61.1	8%	0.077	32%	0.321	C	S	.	.	S	Bend	trans	-136.6	152.9	-179.6	69.1	174.3	0	0	0	109.6	W33 L37 C47 L80 I84	W33-I42 HydrophobicContact CE3-CD1 4.44Å; L37-I42 HydrophobicContact CB-CD1 4.49Å; L37-I42 HydrophobicContact CB-CG1 4.2Å; I42-C47 HydrophobicContact CD1-CB 3.66Å; I42-C47 HydrophobicContact CG1-CB 4.28Å; I42-L80 HydrophobicContact CB-CD2 4.07Å; I42-L80 HydrophobicContact CD1-CD2 4.39Å; I42-L80 HydrophobicContact CG2-CD2 3.35Å; I42-I84 HydrophobicContact CG2-CD1 3.99Å; I42-I84 HydrophobicContact CG2-CG1 4.24Å
43	S	92.9	Very high	92	Very high	46 Å²	46	56.3 Å²	56.3	32%	0.322	30%	0.296	S	S	.	.			trans	-76.9	159.8	176.3	73.6	0	0	0	0	111.9	E45 D46 C47	S43-E45 VanDerWaalsContact C-N 3.25Å; S43-E45 PolarHBondContact O-N 3.28Å; S43-D46 PolarHBondContact O-N 3Å; S43-D46 WeakPolarHBondContact OG-CB 3.27Å; S43-D46 PolarHBondContact OG-N 2.89Å; S43-D46 VanDerWaalsContact OG-N 3.08Å; S43-D46 PolarHBondContact OG-OD2 3Å; S43-C47 WeakPolarHBondContact O-CB 3.27Å; S43-C47 PolarHBondContact O-N 3.13Å
44	A	92.3	Very high	91.8	Very high	65 Å²	65	59 Å²	59	54%	0.537	31%	0.309	S	S	.	.	H	α-helix	trans	-60.9	-37.9	174.7	0	0	0	0	0	111.7	L37 C47 E48	L37-A44 HydrophobicContact CD1-CB 4.13Å; A44-C47 PolarHBondContact O-N 3.14Å; A44-E48 WeakPolarHBondContact O-CB 3.34Å; A44-E48 PolarHBondContact O-N 3.11Å
45	E	93.5	Very high	91.6	Very high	99 Å²	99	62.1 Å²	62.1	46%	0.463	33%	0.325	S	S	.	.	H	α-helix	trans	-62.5	-46.9	176.3	-169.2	-174.6	-158.1	0	0	111.6	S43 C47 E48 F49 Q72 K75	S43-E45 VanDerWaalsContact C-N 3.25Å; S43-E45 PolarHBondContact O-N 3.28Å; E45-C47 VanDerWaalsContact C-N 3.35Å; E45-C47 PolarHBondContact O-N 3.39Å; E45-E48 PolarHBondContact O-N 3.12Å; E45-F49 WeakPolarHBondContact O-CB 3.49Å; E45-F49 PolarHBondContact O-N 3.29Å; E45-Q72 PolarHBondContact OE1-OE1 3.31Å; E45-K75 IonicContact OE2-NZ 2.71Å; E45-K75 PolarHBondContact OE2-NZ 3.49Å
46	D	92.9	Very high	91.3	Very high	4 Å²	4	62.2 Å²	62.2	2%	0.021	32%	0.319	C	S	.	.	H	α-helix	trans	-66.1	-38.1	178.3	-64.4	-31.3	0	0	0	111.4	S43 I50 Q72 T76 N79	S43-D46 PolarHBondContact O-N 3Å; S43-D46 WeakPolarHBondContact OG-CB 3.27Å; S43-D46 PolarHBondContact OG-N 2.89Å; S43-D46 VanDerWaalsContact OG-N 3.08Å; S43-D46 PolarHBondContact OG-OD2 3Å; D46-I50 WeakPolarHBondContact O-CG2 3.37Å; D46-I50 PolarHBondContact O-N 3.24Å; D46-Q72 PolarHBondContact OD1-NE2 3.25Å; D46-Q72 VanDerWaalsContact OD1-NE2 3.13Å; D46-T76 HydrophobicContact CB-CG2 3.96Å; D46-T76 PolarHBondContact OD1-OG1 3.17Å; D46-N79 PolarHBondContact OD2-ND2 2.99Å; D46-N79 VanDerWaalsContact OD2-ND2 3.14Å
47	C	92.8	Very high	90.6	Very high	3 Å²	3	71.6 Å²	71.6	2%	0.02	35%	0.354	C	S	.	.	H	α-helix	trans	-67.1	-42.6	177.3	-171.7	0	0	0	0	112.4	L37 I42 S43 A44 E45 I50 Q51	L37-C47 HydrophobicContact CB-CB 4.34Å; L37-C47 HydrophobicContact CD1-CB 4.45Å; L37-C47 HydrophobicContact CD2-CB 4.16Å; I42-C47 HydrophobicContact CD1-CB 3.66Å; I42-C47 HydrophobicContact CG1-CB 4.28Å; S43-C47 WeakPolarHBondContact O-CB 3.27Å; S43-C47 PolarHBondContact O-N 3.13Å; A44-C47 PolarHBondContact O-N 3.14Å; E45-C47 VanDerWaalsContact C-N 3.35Å; E45-C47 PolarHBondContact O-N 3.39Å; C47-I50 WeakPolarHBondContact O-CG2 3.41Å; C47-Q51 VanDerWaalsContact O-CG 3.27Å; C47-Q51 WeakPolarHBondContact O-CG 3.27Å; C47-Q51 PolarHBondContact O-N 2.98Å; C47-Q51 PolarHBondContact SG-NE2 3.46Å
48	E	93.8	Very high	90.3	Very high	118 Å²	118	70.9 Å²	70.9	55%	0.551	35%	0.353	S	S	*	.	H	α-helix	trans	-67.2	-43.4	177.2	-175.7	-179.4	173.7	0	0	111	A44 E45 R52	A44-E48 WeakPolarHBondContact O-CB 3.34Å; A44-E48 PolarHBondContact O-N 3.11Å; E45-E48 PolarHBondContact O-N 3.12Å; E48-R52 WeakPolarHBondContact O-CG 3.48Å; E48-R52 PolarHBondContact O-N 2.98Å
49	F	94.4	Very high	89.8	Confident	0 Å²	0	66.7 Å²	66.7	0%	0	34%	0.339	C	S	.	.	H	α-helix	trans	-60.4	-50.2	178.7	-178.4	-86.3	0	0	0	111.8	E45 Q51 R52 F53 M65 E69 Q72 C73 T76	E45-F49 WeakPolarHBondContact O-CB 3.49Å; E45-F49 PolarHBondContact O-N 3.29Å; F49-Q51 VanDerWaalsContact C-N 3.32Å; F49-Q51 PolarHBondContact O-N 3Å; F49-R52 PolarHBondContact O-N 3.45Å; F49-F53 HydrophobicContact CE1-CB 4.22Å; F49-F53 HydrophobicContact CE1-CD2 4.45Å; F49-F53 HydrophobicContact CE1-CG 4.48Å; F49-F53 WeakPolarHBondContact O-CB 3.15Å; F49-F53 PolarHBondContact O-N 2.87Å; F49-M65 HydrophobicContact CD1-CE 4.47Å; F49-M65 HydrophobicContact CD2-CE 3.54Å; F49-M65 HydrophobicContact CE1-CE 4.23Å; F49-M65 HydrophobicContact CE2-CE 3.25Å; F49-M65 HydrophobicContact CG-CE 4.15Å; F49-M65 HydrophobicContact CZ-CE 3.61Å; F49-E69 HydrophobicContact CE2-CB 3.91Å; F49-Q72 HydrophobicContact CB-CG 4.34Å; F49-Q72 HydrophobicContact CD2-CB 4.25Å; F49-Q72 HydrophobicContact CD2-CG 3.65Å; F49-Q72 HydrophobicContact CE2-CB 4.34Å; F49-Q72 HydrophobicContact CE2-CG 4.22Å; F49-Q72 HydrophobicContact CG-CG 4.07Å; F49-C73 HydrophobicContact CE1-CB 3.94Å; F49-C73 HydrophobicContact CE2-CB 4.32Å; F49-C73 VanDerWaalsContact CZ-CA 3.43Å; F49-C73 HydrophobicContact CZ-CB 3.46Å; F49-C73 VanDerWaalsContact CZ-CB 3.46Å; F49-T76 HydrophobicContact CD1-CG2 3.93Å
50	I	92.9	Very high	89.6	Confident	0 Å²	0	70.7 Å²	70.7	0%	0	35%	0.345	C	S	.	.	H	α-helix	trans	-64.9	-37.7	-175.7	-163.1	63.5	0	0	0	111.9	W33 D46 C47 F53 E54 T76 F77 L80 M96	W33-I50 HydrophobicContact CB-CG2 4.31Å; W33-I50 HydrophobicContact CD2-CG1 4.33Å; W33-I50 HydrophobicContact CD2-CG2 3.63Å; W33-I50 HydrophobicContact CE3-CG2 4.1Å; W33-I50 HydrophobicContact CG-CG2 3.71Å; W33-I50 HydrophobicContact CH2-CG1 4.14Å; W33-I50 HydrophobicContact CZ2-CG1 3.67Å; W33-I50 HydrophobicContact CZ2-CG2 4.5Å; D46-I50 WeakPolarHBondContact O-CG2 3.37Å; D46-I50 PolarHBondContact O-N 3.24Å; C47-I50 WeakPolarHBondContact O-CG2 3.41Å; I50-F53 PolarHBondContact O-N 3.28Å; I50-E54 WeakPolarHBondContact O-CG 3.38Å; I50-E54 PolarHBondContact O-N 3.35Å; I50-T76 HydrophobicContact CB-CG2 4.33Å; I50-F77 HydrophobicContact CD1-CD1 4.43Å; I50-F77 HydrophobicContact CD1-CE1 3.71Å; I50-F77 HydrophobicContact CD1-CZ 4.24Å; I50-L80 HydrophobicContact CB-CD1 4.34Å; I50-L80 HydrophobicContact CD1-CD1 4.13Å; I50-L80 HydrophobicContact CG1-CD1 4.07Å; I50-M96 HydrophobicContact CD1-CE 3.79Å; I50-M96 HydrophobicContact CD1-SD 4.14Å; I50-M96 HydrophobicContact CG1-CE 4.37Å
51	Q	92.5	Very high	89.5	Confident	67 Å²	67	66.4 Å²	66.4	31%	0.313	33%	0.325	S	S	.	.	H	α-helix	trans	-64.3	-44	175.1	-71.8	176.7	6.9	0	0	111.7	W33 C47 F49 F53 E54 M55	W33-Q51 HydrophobicContact CB-CG 4.44Å; C47-Q51 VanDerWaalsContact O-CG 3.27Å; C47-Q51 WeakPolarHBondContact O-CG 3.27Å; C47-Q51 PolarHBondContact O-N 2.98Å; C47-Q51 PolarHBondContact SG-NE2 3.46Å; F49-Q51 VanDerWaalsContact C-N 3.32Å; F49-Q51 PolarHBondContact O-N 3Å; Q51-F53 VanDerWaalsContact C-N 3.32Å; Q51-F53 PolarHBondContact O-N 3.38Å; Q51-E54 PolarHBondContact O-N 3.33Å; Q51-M55 VanDerWaalsContact O-CG 3.3Å; Q51-M55 WeakPolarHBondContact O-CG 3.45Å; Q51-M55 PolarHBondContact O-N 3.32Å; Q51-M55 VanDerWaalsContact O-N 3.09Å
52	R	92.3	Very high	89.4	Confident	87 Å²	87	64.1 Å²	64.1	33%	0.328	31%	0.313	S	S	.	.	H	α-helix	trans	-63	-39.6	174.9	-73.4	-167.6	-65	126.2	0.7	111.8	E48 F49 M55 K56 M65 E69	E48-R52 WeakPolarHBondContact O-CG 3.48Å; E48-R52 PolarHBondContact O-N 2.98Å; F49-R52 PolarHBondContact O-N 3.45Å; R52-M55 PolarHBondContact O-N 2.74Å; R52-K56 PolarHBondContact O-N 3.5Å; R52-M65 HydrophobicContact CB-CE 3.98Å; R52-E69 IonicContact CZ-OE1 3.82Å; R52-E69 IonicContact CZ-OE2 3.07Å; R52-E69 IonicContact NH1-OE1 2.59Å; R52-E69 PolarHBondContact NH1-OE1 2.95Å; R52-E69 IonicContact NH1-OE2 3.89Å; R52-E69 PolarHBondContact NH1-OE2 3.06Å; R52-E69 IonicContact NH2-OE1 3.5Å; R52-E69 PolarHBondContact NH2-OE1 3.27Å; R52-E69 IonicContact NH2-OE2 2.74Å; R52-E69 PolarHBondContact NH2-OE2 2.89Å
53	F	91	Very high	89.2	Confident	5 Å²	5	65.7 Å²	65.7	2%	0.022	32%	0.319	C	S	.	.	H	α-helix	trans	-64.6	-41.2	178.2	-172.7	-98.9	0	0	0	112.1	F49 I50 Q51 K62 M65 L66 F77 M100	F49-F53 HydrophobicContact CE1-CB 4.22Å; F49-F53 HydrophobicContact CE1-CD2 4.45Å; F49-F53 HydrophobicContact CE1-CG 4.48Å; F49-F53 WeakPolarHBondContact O-CB 3.15Å; F49-F53 PolarHBondContact O-N 2.87Å; I50-F53 PolarHBondContact O-N 3.28Å; Q51-F53 VanDerWaalsContact C-N 3.32Å; Q51-F53 PolarHBondContact O-N 3.38Å; F53-K62 HydrophobicContact CE2-CD 4.4Å; F53-K62 HydrophobicContact CE2-CG 4.4Å; F53-K62 HydrophobicContact CZ-CD 4.24Å; F53-M65 HydrophobicContact CB-CE 4.21Å; F53-M65 HydrophobicContact CD2-SD 4.44Å; F53-L66 HydrophobicContact CE2-CD1 4.29Å; F53-L66 HydrophobicContact CE2-CD2 3.99Å; F53-L66 HydrophobicContact CE2-CG 4.24Å; F53-F77 HydrophobicContact CD1-CZ 4.13Å; F53-F77 AromaticContact CE1-CZ 3.88Å; F53-F77 HydrophobicContact CE1-CZ 3.88Å; F53-F77 HydrophobicContact CZ-CZ 4.37Å; F53-M100 HydrophobicContact CZ-CB 4.49Å; F53-M100 HydrophobicContact CZ-CG 4.39Å; F53-M100 HydrophobicContact CZ-SD 4.32Å
54	E	88.9	Confident	89	Confident	63 Å²	63	69.3 Å²	69.3	29%	0.294	33%	0.331	S	S	.	.	H	α-helix	trans	-67.9	-32.4	175.7	-75.5	179	170.3	0	0	113.4	W33 I50 Q51 K56 Y92 M96	W33-E54 WeakPolarHBondContact CZ2-OE1 3.11Å; W33-E54 PolarHBondContact NE1-OE1 3.24Å; W33-E54 PolarHBondContact NE1-OE2 3.22Å; I50-E54 WeakPolarHBondContact O-CG 3.38Å; I50-E54 PolarHBondContact O-N 3.35Å; Q51-E54 PolarHBondContact O-N 3.33Å; E54-K56 VanDerWaalsContact C-N 3.33Å; E54-Y92 WeakPolarHBondContact OE1-CE1 3.34Å; E54-Y92 PolarHBondContact OE1-OH 3.06Å; E54-M96 HydrophobicContact CG-SD 4.29Å
55	M	87.8	Confident	88.9	Confident	147 Å²	147	66.4 Å²	66.4	72%	0.724	31%	0.307	S	S	*	.	H	α-helix	trans	-68.8	-31.9	179.1	-75	-178.1	-174	0	0	112.7	Q51 R52 R57	Q51-M55 VanDerWaalsContact O-CG 3.3Å; Q51-M55 WeakPolarHBondContact O-CG 3.45Å; Q51-M55 PolarHBondContact O-N 3.32Å; Q51-M55 VanDerWaalsContact O-N 3.09Å; R52-M55 PolarHBondContact O-N 2.74Å; M55-R57 PolarHBondContact O-N 3.07Å
56	K	85.4	Confident	88.7	Confident	52 Å²	52	62 Å²	62	23%	0.226	29%	0.287	C	S	.	.			trans	-74.8	107.7	178.6	-71.9	-178.6	173	-121.4	0	110.6	R52 E54 E61 K62 M65	R52-K56 PolarHBondContact O-N 3.5Å; E54-K56 VanDerWaalsContact C-N 3.33Å; K56-E61 HydrophobicContact CB-CB 4.07Å; K56-E61 HydrophobicContact CD-CB 3.98Å; K56-E61 WeakPolarHBondContact CD-O 3.31Å; K56-E61 HydrophobicContact CG-CB 4.02Å; K56-E61 PolarHBondContact NZ-O 2.87Å; K56-K62 HydrophobicContact CB-CG 4.01Å; K56-K62 WeakPolarHBondContact O-CE 3.41Å; K56-M65 HydrophobicContact CD-CB 4.03Å; K56-M65 HydrophobicContact CD-CG 4.49Å; K56-M65 HydrophobicContact CD-SD 3.63Å
57	R	77.4	Confident	88.6	Confident	227 Å²	227	68.7 Å²	68.7	86%	0.857	32%	0.318	S	S	*	.			trans	-92.4	-27.1	-176.8	-67.8	-172.2	-178.4	176.9	2	113.3	M55	M55-R57 PolarHBondContact O-N 3.07Å
58	S	83.8	Confident	88.4	Confident	32 Å²	32	73.8 Å²	73.8	22%	0.224	35%	0.348	C	S	.	.	S	Bend	trans	-82.8	139.3	-179.6	72.6	0	0	0	0	111.1	E60 E61 K62	S58-E60 WeakPolarHBondContact CB-OE2 3.4Å; S58-E60 PolarHBondContact O-N 3.39Å; S58-E61 PolarHBondContact O-N 3.3Å; S58-E61 VanDerWaalsContact OG-CB 3.22Å; S58-E61 WeakPolarHBondContact OG-CB 3.4Å; S58-E61 WeakPolarHBondContact OG-CG 3.21Å; S58-E61 PolarHBondContact OG-N 2.95Å; S58-E61 VanDerWaalsContact OG-N 3.13Å; S58-E61 PolarHBondContact OG-OE2 3.21Å; S58-K62 PolarHBondContact O-N 3.36Å
59	P	82.8	Confident	88.3	Confident	63 Å²	63	70.9 Å²	70.9	41%	0.409	34%	0.335	S	S	.	.	H	α-helix	trans	-55.2	-32.7	173.3	-26.3	35.1	0	0	0	112.9	Q63	P59-Q63 VanDerWaalsContact O-CB 3.27Å; P59-Q63 WeakPolarHBondContact O-CB 3.42Å; P59-Q63 PolarHBondContact O-N 3.36Å
60	E	85.4	Confident	88.2	Confident	132 Å²	132	71.4 Å²	71.4	62%	0.617	34%	0.341	S	S	*	.	H	α-helix	trans	-69.6	-45.9	-179.6	-61.6	72.2	-155.3	0	0	111.9	S58 K62 Q63 E64	S58-E60 WeakPolarHBondContact CB-OE2 3.4Å; S58-E60 PolarHBondContact O-N 3.39Å; E60-K62 VanDerWaalsContact C-N 3.32Å; E60-K62 PolarHBondContact O-N 3.4Å; E60-Q63 WeakPolarHBondContact O-CB 3.42Å; E60-Q63 PolarHBondContact O-N 2.86Å; E60-Q63 VanDerWaalsContact O-N 3.16Å; E60-E64 PolarHBondContact O-N 3.2Å
61	E	86.6	Confident	88.1	Confident	88 Å²	88	74 Å²	74	41%	0.411	36%	0.358	S	S	.	.	H	α-helix	trans	-63.3	-40.4	176.9	-76.9	165.6	-170.5	0	0	111.6	K56 S58 Q63 M65	K56-E61 HydrophobicContact CB-CB 4.07Å; K56-E61 HydrophobicContact CD-CB 3.98Å; K56-E61 WeakPolarHBondContact CD-O 3.31Å; K56-E61 HydrophobicContact CG-CB 4.02Å; K56-E61 PolarHBondContact NZ-O 2.87Å; S58-E61 PolarHBondContact O-N 3.3Å; S58-E61 VanDerWaalsContact OG-CB 3.22Å; S58-E61 WeakPolarHBondContact OG-CB 3.4Å; S58-E61 WeakPolarHBondContact OG-CG 3.21Å; S58-E61 PolarHBondContact OG-N 2.95Å; S58-E61 VanDerWaalsContact OG-N 3.13Å; S58-E61 PolarHBondContact OG-OE2 3.21Å; E61-Q63 VanDerWaalsContact C-N 3.34Å; E61-M65 PolarHBondContact O-N 2.83Å; E61-M65 VanDerWaalsContact O-N 3.12Å
62	K	86.3	Confident	88.2	Confident	34 Å²	34	72 Å²	72	15%	0.148	35%	0.35	C	S	.	.	H	α-helix	trans	-63.7	-43	173.8	-71.3	-174.8	-172.7	174.6	0	110.4	F53 K56 S58 E60 E64 M65 L66 E103	F53-K62 HydrophobicContact CE2-CD 4.4Å; F53-K62 HydrophobicContact CE2-CG 4.4Å; F53-K62 HydrophobicContact CZ-CD 4.24Å; K56-K62 HydrophobicContact CB-CG 4.01Å; K56-K62 WeakPolarHBondContact O-CE 3.41Å; S58-K62 PolarHBondContact O-N 3.36Å; E60-K62 VanDerWaalsContact C-N 3.32Å; E60-K62 PolarHBondContact O-N 3.4Å; K62-E64 PolarHBondContact O-N 3.24Å; K62-M65 PolarHBondContact O-N 2.98Å; K62-L66 WeakPolarHBondContact O-CB 3.44Å; K62-L66 WeakPolarHBondContact O-CG 3.34Å; K62-L66 PolarHBondContact O-N 2.77Å; K62-E103 IonicContact NZ-OE1 3.49Å; K62-E103 PolarHBondContact NZ-OE1 3.07Å; K62-E103 VanDerWaalsContact NZ-OE1 3.09Å
63	Q	87.6	Confident	88.3	Confident	47 Å²	47	67.9 Å²	67.9	22%	0.22	33%	0.334	C	S	.	.	H	α-helix	trans	-60.1	-45.5	178.4	-177.1	64.2	26.1	0	0	111.9	P59 E60 E61 L66 Q67 N104 R107	P59-Q63 VanDerWaalsContact O-CB 3.27Å; P59-Q63 WeakPolarHBondContact O-CB 3.42Å; P59-Q63 PolarHBondContact O-N 3.36Å; E60-Q63 WeakPolarHBondContact O-CB 3.42Å; E60-Q63 PolarHBondContact O-N 2.86Å; E60-Q63 VanDerWaalsContact O-N 3.16Å; E61-Q63 VanDerWaalsContact C-N 3.34Å; Q63-L66 PolarHBondContact O-N 3.42Å; Q63-Q67 WeakPolarHBondContact O-CB 3.35Å; Q63-Q67 VanDerWaalsContact O-CG 3.31Å; Q63-Q67 WeakPolarHBondContact O-CG 3.42Å; Q63-Q67 PolarHBondContact O-N 3.09Å; Q63-N104 PolarHBondContact OE1-ND2 2.8Å; Q63-R107 VanDerWaalsContact OE1-NE 3.07Å
64	E	88.6	Confident	88.4	Confident	123 Å²	123	67.7 Å²	67.7	58%	0.575	33%	0.333	S	S	*	.	H	α-helix	trans	-60.9	-44.8	177	-174.4	-175.1	-168.7	0	0	111.8	E60 K62 Q67 T68	E60-E64 PolarHBondContact O-N 3.2Å; K62-E64 PolarHBondContact O-N 3.24Å; E64-Q67 PolarHBondContact O-N 3.17Å; E64-T68 PolarHBondContact O-N 3.39Å; E64-T68 PolarHBondContact O-OG1 3.29Å
65	M	90.1	Very high	88.7	Confident	3 Å²	3	67.6 Å²	67.6	2%	0.015	33%	0.332	C	S	.	.	H	α-helix	trans	-64	-41.5	176.9	-177.4	171.7	173.5	0	0	112	F49 R52 F53 K56 E61 K62 Q67 T68 E69	F49-M65 HydrophobicContact CD1-CE 4.47Å; F49-M65 HydrophobicContact CD2-CE 3.54Å; F49-M65 HydrophobicContact CE1-CE 4.23Å; F49-M65 HydrophobicContact CE2-CE 3.25Å; F49-M65 HydrophobicContact CG-CE 4.15Å; F49-M65 HydrophobicContact CZ-CE 3.61Å; R52-M65 HydrophobicContact CB-CE 3.98Å; F53-M65 HydrophobicContact CB-CE 4.21Å; F53-M65 HydrophobicContact CD2-SD 4.44Å; K56-M65 HydrophobicContact CD-CB 4.03Å; K56-M65 HydrophobicContact CD-CG 4.49Å; K56-M65 HydrophobicContact CD-SD 3.63Å; E61-M65 PolarHBondContact O-N 2.83Å; E61-M65 VanDerWaalsContact O-N 3.12Å; K62-M65 PolarHBondContact O-N 2.98Å; M65-Q67 VanDerWaalsContact C-N 3.33Å; M65-Q67 PolarHBondContact O-N 2.9Å; M65-T68 PolarHBondContact O-N 2.94Å; M65-T68 PolarHBondContact O-OG1 3.18Å; M65-E69 WeakPolarHBondContact O-CA 3.43Å; M65-E69 WeakPolarHBondContact O-CB 3.29Å; M65-E69 PolarHBondContact O-N 3.14Å
66	L	90.4	Very high	89.1	Confident	8 Å²	8	60.6 Å²	60.6	4%	0.042	30%	0.297	C	S	.	.	H	α-helix	trans	-71.2	-28.4	179.6	-69	173.1	0	0	0	112.6	F53 K62 Q63 G70 C73 M100 R107 I110	F53-L66 HydrophobicContact CE2-CD1 4.29Å; F53-L66 HydrophobicContact CE2-CD2 3.99Å; F53-L66 HydrophobicContact CE2-CG 4.24Å; K62-L66 WeakPolarHBondContact O-CB 3.44Å; K62-L66 WeakPolarHBondContact O-CG 3.34Å; K62-L66 PolarHBondContact O-N 2.77Å; Q63-L66 PolarHBondContact O-N 3.42Å; L66-G70 WeakPolarHBondContact O-CA 3.43Å; L66-G70 PolarHBondContact O-N 3.17Å; L66-G70 VanDerWaalsContact O-N 3.08Å; L66-C73 HydrophobicContact CD2-CB 3.76Å; L66-C73 WeakPolarHBondContact CD2-SG 3.49Å; L66-M100 HydrophobicContact CD1-CG 3.9Å; L66-M100 HydrophobicContact CD1-SD 3.86Å; L66-M100 HydrophobicContact CD2-SD 3.89Å; L66-R107 HydrophobicContact CD1-CG 4.37Å; L66-I110 HydrophobicContact CB-CD1 4.06Å; L66-I110 HydrophobicContact CD2-CD1 4.15Å; L66-I110 HydrophobicContact CG-CD1 4.47Å
67	Q	89.3	Confident	89.6	Confident	144 Å²	144	58.1 Å²	58.1	67%	0.673	29%	0.286	S	S	*	.	H	α-helix	trans	-69.7	-36	173.6	-78.1	174.1	-8.7	0	0	112.5	Q63 E64 M65	Q63-Q67 WeakPolarHBondContact O-CB 3.35Å; Q63-Q67 VanDerWaalsContact O-CG 3.31Å; Q63-Q67 WeakPolarHBondContact O-CG 3.42Å; Q63-Q67 PolarHBondContact O-N 3.09Å; E64-Q67 PolarHBondContact O-N 3.17Å; M65-Q67 VanDerWaalsContact C-N 3.33Å; M65-Q67 PolarHBondContact O-N 2.9Å
68	T	89.4	Confident	90.3	Very high	109 Å²	109	47.6 Å²	47.6	67%	0.669	25%	0.247	S	C	*	.	H	α-helix	trans	-86.8	-42.7	179.8	33.2	0	0	0	0	112.7	E64 M65	E64-T68 PolarHBondContact O-N 3.39Å; E64-T68 PolarHBondContact O-OG1 3.29Å; M65-T68 PolarHBondContact O-N 2.94Å; M65-T68 PolarHBondContact O-OG1 3.18Å
69	E	92	Very high	90.8	Very high	57 Å²	57	47.8 Å²	47.8	27%	0.266	25%	0.245	S	C	.	.	H	α-helix	trans	-115.3	23.3	-170.5	-59.9	-177.1	-128.2	0	0	113.3	F49 R52 M65 S71 Q72 C73	F49-E69 HydrophobicContact CE2-CB 3.91Å; R52-E69 IonicContact CZ-OE1 3.82Å; R52-E69 IonicContact CZ-OE2 3.07Å; R52-E69 IonicContact NH1-OE1 2.59Å; R52-E69 PolarHBondContact NH1-OE1 2.95Å; R52-E69 IonicContact NH1-OE2 3.89Å; R52-E69 PolarHBondContact NH1-OE2 3.06Å; R52-E69 IonicContact NH2-OE1 3.5Å; R52-E69 PolarHBondContact NH2-OE1 3.27Å; R52-E69 IonicContact NH2-OE2 2.74Å; R52-E69 PolarHBondContact NH2-OE2 2.89Å; M65-E69 WeakPolarHBondContact O-CA 3.43Å; M65-E69 WeakPolarHBondContact O-CB 3.29Å; M65-E69 PolarHBondContact O-N 3.14Å; E69-S71 VanDerWaalsContact C-N 3.32Å; E69-S71 PolarHBondContact O-N 3.38Å; E69-Q72 HydrophobicContact CB-CB 4.49Å; E69-Q72 PolarHBondContact O-N 3.03Å; E69-C73 PolarHBondContact O-N 3.26Å
70	G	91.2	Very high	91.3	Very high	12 Å²	12	44.8 Å²	44.8	12%	0.124	23%	0.226	C	C	.	.	H	α-helix	trans	-53.6	-42.2	-176.5	0	0	0	0	0	114.2	L66 Q72 C73 A74 I110	L66-G70 WeakPolarHBondContact O-CA 3.43Å; L66-G70 PolarHBondContact O-N 3.17Å; L66-G70 VanDerWaalsContact O-N 3.08Å; G70-Q72 VanDerWaalsContact C-N 3.29Å; G70-Q72 PolarHBondContact O-N 3.3Å; G70-C73 VanDerWaalsContact O-CB 3.24Å; G70-C73 WeakPolarHBondContact O-CB 3.47Å; G70-C73 PolarHBondContact O-N 2.93Å; G70-C73 VanDerWaalsContact O-N 3.17Å; G70-A74 PolarHBondContact O-N 2.94Å; G70-A74 VanDerWaalsContact O-N 3.08Å; G70-I110 WeakPolarHBondContact O-CG2 3.4Å
71	S	91.9	Very high	91.6	Very high	53 Å²	53	38.5 Å²	38.5	37%	0.371	20%	0.196	S	C	.	.	H	α-helix	trans	-63.8	-35.2	178	-170.5	0	0	0	0	112.7	E69 K75 Y114	E69-S71 VanDerWaalsContact C-N 3.32Å; E69-S71 PolarHBondContact O-N 3.38Å; S71-K75 WeakPolarHBondContact O-CB 3.3Å; S71-K75 PolarHBondContact O-N 2.95Å; S71-K75 VanDerWaalsContact O-N 3.17Å; S71-Y114 WeakPolarHBondContact O-CD2 3.24Å
72	Q	93.4	Very high	91.8	Very high	27 Å²	27	38.2 Å²	38.2	13%	0.126	20%	0.201	C	C	.	.	H	α-helix	trans	-72.8	-35.1	176.4	-177.6	54.1	28.6	0	0	110.8	E45 D46 F49 E69 G70 K75 T76	E45-Q72 PolarHBondContact OE1-OE1 3.31Å; D46-Q72 PolarHBondContact OD1-NE2 3.25Å; D46-Q72 VanDerWaalsContact OD1-NE2 3.13Å; F49-Q72 HydrophobicContact CB-CG 4.34Å; F49-Q72 HydrophobicContact CD2-CB 4.25Å; F49-Q72 HydrophobicContact CD2-CG 3.65Å; F49-Q72 HydrophobicContact CE2-CB 4.34Å; F49-Q72 HydrophobicContact CE2-CG 4.22Å; F49-Q72 HydrophobicContact CG-CG 4.07Å; E69-Q72 HydrophobicContact CB-CB 4.49Å; E69-Q72 PolarHBondContact O-N 3.03Å; G70-Q72 VanDerWaalsContact C-N 3.29Å; G70-Q72 PolarHBondContact O-N 3.3Å; Q72-K75 PolarHBondContact O-N 3.42Å; Q72-T76 PolarHBondContact NE2-OG1 2.84Å; Q72-T76 VanDerWaalsContact O-CB 3.29Å; Q72-T76 WeakPolarHBondContact O-CB 3.17Å; Q72-T76 PolarHBondContact O-N 3.35Å; Q72-T76 PolarHBondContact O-OG1 3.22Å
73	C	94.6	Very high	92	Very high	0 Å²	0	41.2 Å²	41.2	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-56.6	-54.4	172.9	-176.4	0	0	0	0	112.3	F49 L66 E69 G70 K75 T76 F77 I110	F49-C73 HydrophobicContact CE1-CB 3.94Å; F49-C73 HydrophobicContact CE2-CB 4.32Å; F49-C73 VanDerWaalsContact CZ-CA 3.43Å; F49-C73 HydrophobicContact CZ-CB 3.46Å; F49-C73 VanDerWaalsContact CZ-CB 3.46Å; L66-C73 HydrophobicContact CD2-CB 3.76Å; L66-C73 WeakPolarHBondContact CD2-SG 3.49Å; E69-C73 PolarHBondContact O-N 3.26Å; G70-C73 VanDerWaalsContact O-CB 3.24Å; G70-C73 WeakPolarHBondContact O-CB 3.47Å; G70-C73 PolarHBondContact O-N 2.93Å; G70-C73 VanDerWaalsContact O-N 3.17Å; C73-K75 PolarHBondContact O-N 3.43Å; C73-T76 PolarHBondContact O-N 3.08Å; C73-F77 WeakPolarHBondContact O-CD2 3.35Å; C73-F77 PolarHBondContact O-N 2.97Å; C73-F77 VanDerWaalsContact SG-CD2 3.55Å; C73-F77 WeakPolarHBondContact SG-CE2 3.19Å; C73-I110 HydrophobicContact CB-CG2 4.46Å
74	A	94.2	Very high	92.1	Very high	0 Å²	0	39 Å²	39	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-60.7	-46.8	178.2	0	0	0	0	0	112	G70 T76 F77 I78 I110 F111 Y114	G70-A74 PolarHBondContact O-N 2.94Å; G70-A74 VanDerWaalsContact O-N 3.08Å; A74-T76 VanDerWaalsContact C-N 3.34Å; A74-T76 PolarHBondContact O-N 2.98Å; A74-F77 PolarHBondContact O-N 3.03Å; A74-I78 WeakPolarHBondContact O-CB 3.45Å; A74-I78 WeakPolarHBondContact O-CD1 3.32Å; A74-I78 VanDerWaalsContact O-CG1 3.22Å; A74-I78 WeakPolarHBondContact O-CG1 3.47Å; A74-I78 PolarHBondContact O-N 3.39Å; A74-I110 HydrophobicContact CB-CG2 4.06Å; A74-F111 HydrophobicContact CB-CD1 3.87Å; A74-F111 HydrophobicContact CB-CE1 4.22Å; A74-Y114 HydrophobicContact CB-CD1 4.02Å; A74-Y114 HydrophobicContact CB-CD2 4.18Å; A74-Y114 HydrophobicContact CB-CG 3.62Å
75	K	94.8	Very high	92.1	Very high	62 Å²	62	37.8 Å²	37.8	27%	0.27	21%	0.209	S	C	.	.	H	α-helix	trans	-54.3	-50.6	176.1	-177.6	-176.2	166.5	-162.2	0	111.3	E45 S71 Q72 C73 I78 N79 Y114	E45-K75 IonicContact OE2-NZ 2.71Å; E45-K75 PolarHBondContact OE2-NZ 3.49Å; S71-K75 WeakPolarHBondContact O-CB 3.3Å; S71-K75 PolarHBondContact O-N 2.95Å; S71-K75 VanDerWaalsContact O-N 3.17Å; Q72-K75 PolarHBondContact O-N 3.42Å; C73-K75 PolarHBondContact O-N 3.43Å; K75-I78 PolarHBondContact O-N 3.44Å; K75-N79 VanDerWaalsContact O-CB 3.27Å; K75-N79 WeakPolarHBondContact O-CB 3.39Å; K75-N79 PolarHBondContact O-N 3.17Å; K75-N79 PolarHBondContact O-OD1 3.21Å; K75-Y114 HydrophobicContact CB-CD2 4.35Å; K75-Y114 HydrophobicContact CB-CE2 3.58Å; K75-Y114 HydrophobicContact CG-CE2 4.21Å
76	T	95.1	Very high	92.1	Very high	0 Å²	0	43 Å²	43	0%	0	23%	0.231	C	C	.	.	H	α-helix	trans	-59.1	-55.7	-178.9	-57.9	0	0	0	0	109.9	D46 F49 I50 Q72 C73 A74 I78 N79 L80	D46-T76 HydrophobicContact CB-CG2 3.96Å; D46-T76 PolarHBondContact OD1-OG1 3.17Å; F49-T76 HydrophobicContact CD1-CG2 3.93Å; I50-T76 HydrophobicContact CB-CG2 4.33Å; Q72-T76 PolarHBondContact NE2-OG1 2.84Å; Q72-T76 VanDerWaalsContact O-CB 3.29Å; Q72-T76 WeakPolarHBondContact O-CB 3.17Å; Q72-T76 PolarHBondContact O-N 3.35Å; Q72-T76 PolarHBondContact O-OG1 3.22Å; C73-T76 PolarHBondContact O-N 3.08Å; A74-T76 VanDerWaalsContact C-N 3.34Å; A74-T76 PolarHBondContact O-N 2.98Å; T76-I78 PolarHBondContact O-N 2.74Å; T76-N79 PolarHBondContact O-N 2.84Å; T76-L80 HydrophobicContact CG2-CD1 3.71Å; T76-L80 HydrophobicContact CG2-CG 4.09Å; T76-L80 WeakPolarHBondContact O-CB 3.37Å; T76-L80 WeakPolarHBondContact O-CG 3.38Å; T76-L80 PolarHBondContact O-N 3.08Å
77	F	95.7	Very high	92.1	Very high	0 Å²	0	45.3 Å²	45.3	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-60.8	-41.9	-178.4	-74.8	-52.7	0	0	0	113.2	I50 F53 C73 A74 L80 M81 I93 M96 V97 M100 F111	I50-F77 HydrophobicContact CD1-CD1 4.43Å; I50-F77 HydrophobicContact CD1-CE1 3.71Å; I50-F77 HydrophobicContact CD1-CZ 4.24Å; F53-F77 HydrophobicContact CD1-CZ 4.13Å; F53-F77 AromaticContact CE1-CZ 3.88Å; F53-F77 HydrophobicContact CE1-CZ 3.88Å; F53-F77 HydrophobicContact CZ-CZ 4.37Å; C73-F77 WeakPolarHBondContact O-CD2 3.35Å; C73-F77 PolarHBondContact O-N 2.97Å; C73-F77 VanDerWaalsContact SG-CD2 3.55Å; C73-F77 WeakPolarHBondContact SG-CE2 3.19Å; A74-F77 PolarHBondContact O-N 3.03Å; F77-L80 PolarHBondContact O-N 3.49Å; F77-M81 WeakPolarHBondContact O-CB 3.35Å; F77-M81 WeakPolarHBondContact O-CE 3.46Å; F77-M81 VanDerWaalsContact O-CG 3.27Å; F77-M81 WeakPolarHBondContact O-CG 3.37Å; F77-M81 PolarHBondContact O-N 2.77Å; F77-I93 HydrophobicContact CD1-CG2 3.93Å; F77-M96 HydrophobicContact CE1-CB 4.12Å; F77-M96 HydrophobicContact CE1-CE 4Å; F77-M96 HydrophobicContact CE1-SD 4.49Å; F77-M96 HydrophobicContact CZ-CB 4.31Å; F77-V97 HydrophobicContact CB-CG2 4.03Å; F77-V97 HydrophobicContact CD1-CG2 3.78Å; F77-V97 HydrophobicContact CD2-CG2 4Å; F77-V97 HydrophobicContact CE1-CG2 4.18Å; F77-V97 HydrophobicContact CE2-CG2 4.37Å; F77-V97 HydrophobicContact CG-CG2 3.68Å; F77-V97 HydrophobicContact CZ-CG2 4.46Å; F77-M100 HydrophobicContact CE2-CE 4.49Å; F77-M100 HydrophobicContact CE2-SD 4.06Å; F77-F111 HydrophobicContact CB-CE1 4.33Å; F77-F111 HydrophobicContact CD2-CZ 4.34Å
78	I	94.1	Very high	92.2	Very high	6 Å²	6	43.7 Å²	43.7	3%	0.031	23%	0.234	C	C	.	.	H	α-helix	trans	-64.4	-46.3	178.2	-69.1	166.6	0	0	0	110.9	A74 K75 T76 M81 T82 F111 Y114 Y125	A74-I78 WeakPolarHBondContact O-CB 3.45Å; A74-I78 WeakPolarHBondContact O-CD1 3.32Å; A74-I78 VanDerWaalsContact O-CG1 3.22Å; A74-I78 WeakPolarHBondContact O-CG1 3.47Å; A74-I78 PolarHBondContact O-N 3.39Å; K75-I78 PolarHBondContact O-N 3.44Å; T76-I78 PolarHBondContact O-N 2.74Å; I78-M81 HydrophobicContact CG1-CE 4.33Å; I78-M81 PolarHBondContact O-N 2.95Å; I78-T82 WeakPolarHBondContact O-CB 3.43Å; I78-T82 PolarHBondContact O-N 3.44Å; I78-T82 PolarHBondContact O-OG1 3.25Å; I78-F111 HydrophobicContact CD1-CD1 4.32Å; I78-Y114 HydrophobicContact CD1-CD1 3.57Å; I78-Y114 HydrophobicContact CD1-CE1 3.58Å; I78-Y125 HydrophobicContact CD1-CD1 4.18Å; I78-Y125 HydrophobicContact CD1-CD2 3.68Å; I78-Y125 HydrophobicContact CD1-CE1 4.49Å; I78-Y125 HydrophobicContact CD1-CE2 4.04Å; I78-Y125 HydrophobicContact CD1-CG 3.77Å; I78-Y125 HydrophobicContact CG1-CD1 4.42Å; I78-Y125 HydrophobicContact CG1-CD2 4.47Å; I78-Y125 HydrophobicContact CG1-CG 4.09Å; I78-Y125 HydrophobicContact CG2-CD1 3.47Å; I78-Y125 VanDerWaalsContact CG2-CD1 3.47Å; I78-Y125 HydrophobicContact CG2-CE1 3.95Å; I78-Y125 HydrophobicContact CG2-CG 3.99Å
79	N	92.9	Very high	92.4	Very high	35 Å²	35	38.7 Å²	38.7	19%	0.187	20%	0.204	C	C	.	.	H	α-helix	trans	-60.9	-47	177.2	-74.9	-4.5	0	0	0	111.2	D46 K75 T76 M81 T82 H83	D46-N79 PolarHBondContact OD2-ND2 2.99Å; D46-N79 VanDerWaalsContact OD2-ND2 3.14Å; K75-N79 VanDerWaalsContact O-CB 3.27Å; K75-N79 WeakPolarHBondContact O-CB 3.39Å; K75-N79 PolarHBondContact O-N 3.17Å; K75-N79 PolarHBondContact O-OD1 3.21Å; T76-N79 PolarHBondContact O-N 2.84Å; N79-M81 PolarHBondContact O-N 3.35Å; N79-T82 PolarHBondContact O-N 2.98Å; N79-H83 WeakPolarHBondContact O-CB 3.45Å; N79-H83 PolarHBondContact O-CD2 3.45Å; N79-H83 PolarHBondContact O-N 3.09Å
80	L	93.1	Very high	92.5	Very high	0 Å²	0	36 Å²	36	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-60.5	-44.4	179.4	-67.3	179.6	0	0	0	111.4	W33 I42 I50 T76 F77 T82 I84 I93	W33-L80 HydrophobicContact CE3-CD2 4.49Å; W33-L80 HydrophobicContact CH2-CD1 4.17Å; W33-L80 HydrophobicContact CZ3-CD1 4Å; W33-L80 HydrophobicContact CZ3-CD2 4.08Å; I42-L80 HydrophobicContact CB-CD2 4.07Å; I42-L80 HydrophobicContact CD1-CD2 4.39Å; I42-L80 HydrophobicContact CG2-CD2 3.35Å; I50-L80 HydrophobicContact CB-CD1 4.34Å; I50-L80 HydrophobicContact CD1-CD1 4.13Å; I50-L80 HydrophobicContact CG1-CD1 4.07Å; T76-L80 HydrophobicContact CG2-CD1 3.71Å; T76-L80 HydrophobicContact CG2-CG 4.09Å; T76-L80 WeakPolarHBondContact O-CB 3.37Å; T76-L80 WeakPolarHBondContact O-CG 3.38Å; T76-L80 PolarHBondContact O-N 3.08Å; F77-L80 PolarHBondContact O-N 3.49Å; L80-T82 VanDerWaalsContact C-N 3.33Å; L80-T82 PolarHBondContact O-N 3.42Å; L80-I84 HydrophobicContact CB-CD1 4.28Å; L80-I84 HydrophobicContact CD2-CD1 3.84Å; L80-I84 WeakPolarHBondContact O-CB 3.29Å; L80-I84 WeakPolarHBondContact O-CG1 3.48Å; L80-I84 PolarHBondContact O-N 2.91Å; L80-I84 VanDerWaalsContact O-N 3.12Å; L80-I93 HydrophobicContact CB-CD1 3.61Å; L80-I93 HydrophobicContact CB-CG1 4.27Å; L80-I93 HydrophobicContact CD1-CG1 4.46Å
81	M	93	Very high	92.6	Very high	0 Å²	0	36.7 Å²	36.7	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-66.1	-34	176.8	-70.7	-175	-61.7	0	0	113	F77 I78 N79 I93 L94 F126 M129	F77-M81 WeakPolarHBondContact O-CB 3.35Å; F77-M81 WeakPolarHBondContact O-CE 3.46Å; F77-M81 VanDerWaalsContact O-CG 3.27Å; F77-M81 WeakPolarHBondContact O-CG 3.37Å; F77-M81 PolarHBondContact O-N 2.77Å; I78-M81 HydrophobicContact CG1-CE 4.33Å; I78-M81 PolarHBondContact O-N 2.95Å; N79-M81 PolarHBondContact O-N 3.35Å; M81-I93 HydrophobicContact CG-CB 4.43Å; M81-I93 HydrophobicContact CG-CG2 3.49Å; M81-I93 VanDerWaalsContact CG-CG2 3.49Å; M81-I93 HydrophobicContact SD-CG2 4.32Å; M81-L94 HydrophobicContact SD-CD2 3.48Å; M81-L94 WeakPolarHBondContact SD-CD2 3.43Å; M81-L94 HydrophobicContact SD-CG 4.37Å; M81-F126 HydrophobicContact CE-CD1 4.09Å; M81-F126 HydrophobicContact CE-CE1 3.58Å; M81-F126 HydrophobicContact CE-CZ 4.06Å; M81-F126 HydrophobicContact SD-CD1 4.36Å; M81-F126 HydrophobicContact SD-CE1 4.1Å; M81-M129 HydrophobicContact CB-CE 3.93Å; M81-M129 WeakPolarHBondContact O-CE 3.49Å
82	T	89.7	Confident	92.8	Very high	82 Å²	82	35.7 Å²	35.7	50%	0.503	18%	0.18	S	C	.	.	H	α-helix	trans	-80.2	-42.9	-175.5	-55.7	0	0	0	0	112	I78 N79 L80	I78-T82 WeakPolarHBondContact O-CB 3.43Å; I78-T82 PolarHBondContact O-N 3.44Å; I78-T82 PolarHBondContact O-OG1 3.25Å; N79-T82 PolarHBondContact O-N 2.98Å; L80-T82 VanDerWaalsContact C-N 3.33Å; L80-T82 PolarHBondContact O-N 3.42Å
83	H	90.1	Very high	92.8	Very high	98 Å²	98	34.4 Å²	34.4	45%	0.454	17%	0.174	S	C	.	.	H	α-helix	trans	-89.9	-27.3	-173.6	-64	-58.9	0	0	0	113.3	M41 N79	M41-H83 WeakPolarHBondContact CE-O 3.22Å; M41-H83 WeakPolarHBondContact O-CB 3.03Å; N79-H83 WeakPolarHBondContact O-CB 3.45Å; N79-H83 PolarHBondContact O-CD2 3.45Å; N79-H83 PolarHBondContact O-N 3.09Å
84	I	90.6	Very high	92.8	Very high	1 Å²	1	34.4 Å²	34.4	1%	0.005	17%	0.174	C	C	.	.			trans	-86.4	119.8	-177.9	-58.8	176.5	0	0	0	110.7	W33 Y36 I42 L80 K86 T89 V90 I93 R132	W33-I84 HydrophobicContact CZ3-CD1 4.12Å; Y36-I84 HydrophobicContact CD2-CD1 4.42Å; Y36-I84 HydrophobicContact CE1-CG2 4.08Å; Y36-I84 HydrophobicContact CG-CD1 4.39Å; I42-I84 HydrophobicContact CG2-CD1 3.99Å; I42-I84 HydrophobicContact CG2-CG1 4.24Å; L80-I84 HydrophobicContact CB-CD1 4.28Å; L80-I84 HydrophobicContact CD2-CD1 3.84Å; L80-I84 WeakPolarHBondContact O-CB 3.29Å; L80-I84 WeakPolarHBondContact O-CG1 3.48Å; L80-I84 PolarHBondContact O-N 2.91Å; L80-I84 VanDerWaalsContact O-N 3.12Å; I84-K86 HydrophobicContact CG2-CB 4.15Å; I84-T89 HydrophobicContact CD1-CG2 3.85Å; I84-T89 HydrophobicContact CG2-CG2 3.93Å; I84-V90 HydrophobicContact CG2-CG2 4.43Å; I84-V90 VanDerWaalsContact O-CG2 3.23Å; I84-V90 WeakPolarHBondContact O-CG2 3.25Å; I84-I93 HydrophobicContact CD1-CD1 4.15Å; I84-R132 PolarHBondContact O-NH2 3.49Å
85	C	87.6	Confident	92.8	Very high	96 Å²	96	34.5 Å²	34.5	65%	0.649	17%	0.174	S	C	*	.			trans	-89.4	-18.8	175.3	-56.7	0	0	0	0	113.5	E87	C85-E87 PolarHBondContact O-N 3.47Å; C85-E87 VanDerWaalsContact O-N 3.14Å
86	K	91.4	Very high	92.8	Very high	112 Å²	112	32.5 Å²	32.5	49%	0.487	17%	0.166	S	C	.	.			trans	-68	111.9	-177.8	-169.9	-172.5	-174.8	-177.4	0	110.8	Y36 I84 Q88 T89 V90	Y36-K86 WeakPolarHBondContact OH-CB 2.96Å; Y36-K86 WeakPolarHBondContact OH-CD 3.24Å; I84-K86 HydrophobicContact CG2-CB 4.15Å; K86-Q88 PolarHBondContact O-N 3.2Å; K86-T89 PolarHBondContact O-N 3.38Å; K86-V90 PolarHBondContact O-N 2.97Å; K86-V90 VanDerWaalsContact O-N 3.13Å
87	E	90.7	Very high	92.8	Very high	58 Å²	58	32.5 Å²	32.5	27%	0.271	17%	0.166	S	C	.	.	H	α-helix	trans	-51.7	-51.5	-175	-71.2	-60.5	147	0	0	113.4	C85 T89 V90 Q91 R132 D134 T137	C85-E87 PolarHBondContact O-N 3.47Å; C85-E87 VanDerWaalsContact O-N 3.14Å; E87-T89 PolarHBondContact O-N 3.48Å; E87-T89 VanDerWaalsContact O-N 3.08Å; E87-V90 PolarHBondContact O-N 3.47Å; E87-Q91 VanDerWaalsContact O-CG 3.29Å; E87-Q91 WeakPolarHBondContact O-CG 3.48Å; E87-Q91 PolarHBondContact O-N 2.95Å; E87-R132 IonicContact OE1-CZ 3.93Å; E87-R132 IonicContact OE1-NH1 2.89Å; E87-R132 PolarHBondContact OE1-NH1 2.86Å; E87-D134 WeakPolarHBondContact OE2-CB 3.45Å; E87-T137 PolarHBondContact OE2-OG1 3Å
88	Q	91.7	Very high	92.7	Very high	109 Å²	109	33.1 Å²	33.1	51%	0.509	17%	0.169	S	C	.	.	H	α-helix	trans	-53.5	-35.8	179	-70.8	175.5	-15.3	0	0	113.7	K86 Y92	K86-Q88 PolarHBondContact O-N 3.2Å; Q88-Y92 WeakPolarHBondContact O-CB 3.41Å; Q88-Y92 PolarHBondContact O-N 3.24Å; Q88-Y92 VanDerWaalsContact O-N 3.17Å
89	T	92.6	Very high	92.6	Very high	4 Å²	4	35.3 Å²	35.3	3%	0.025	18%	0.181	C	C	.	.	H	α-helix	trans	-77.3	-38.5	178.5	-62.9	0	0	0	0	111.2	V31 W33 Y36 I84 K86 E87 Y92 I93	V31-T89 HydrophobicContact CG1-CG2 3.83Å; W33-T89 HydrophobicContact CH2-CG2 3.98Å; W33-T89 HydrophobicContact CZ3-CG2 3.87Å; Y36-T89 HydrophobicContact CE2-CG2 3.9Å; Y36-T89 WeakPolarHBondContact OH-CB 3.46Å; Y36-T89 PolarHBondContact OH-OG1 3.36Å; I84-T89 HydrophobicContact CD1-CG2 3.85Å; I84-T89 HydrophobicContact CG2-CG2 3.93Å; K86-T89 PolarHBondContact O-N 3.38Å; E87-T89 PolarHBondContact O-N 3.48Å; E87-T89 VanDerWaalsContact O-N 3.08Å; T89-Y92 WeakPolarHBondContact O-CB 3.47Å; T89-Y92 PolarHBondContact O-N 3.11Å; T89-I93 HydrophobicContact CG2-CD1 3.84Å; T89-I93 HydrophobicContact CG2-CG1 4.44Å; T89-I93 VanDerWaalsContact O-CD1 3.31Å; T89-I93 WeakPolarHBondContact O-CD1 3.29Å; T89-I93 WeakPolarHBondContact O-CG1 3.35Å; T89-I93 PolarHBondContact O-N 3.37Å
90	V	93.8	Very high	92.6	Very high	0 Å²	0	33.7 Å²	33.7	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-62.9	-43	173.5	-178.7	0	0	0	0	111.1	I84 K86 E87 Y92 I93 L94 T137	I84-V90 HydrophobicContact CG2-CG2 4.43Å; I84-V90 VanDerWaalsContact O-CG2 3.23Å; I84-V90 WeakPolarHBondContact O-CG2 3.25Å; K86-V90 PolarHBondContact O-N 2.97Å; K86-V90 VanDerWaalsContact O-N 3.13Å; E87-V90 PolarHBondContact O-N 3.47Å; V90-Y92 VanDerWaalsContact C-N 3.29Å; V90-Y92 PolarHBondContact O-N 2.74Å; V90-I93 PolarHBondContact O-N 2.95Å; V90-L94 HydrophobicContact CG1-CD1 4.05Å; V90-L94 HydrophobicContact CG1-CG 4.37Å; V90-L94 WeakPolarHBondContact O-CG 3.37Å; V90-L94 PolarHBondContact O-N 3.26Å; V90-T137 HydrophobicContact CG1-CG2 3.91Å
91	Q	94.2	Very high	92.6	Very high	27 Å²	27	33.7 Å²	33.7	13%	0.126	17%	0.172	C	C	.	.	H	α-helix	trans	-56.5	-44.8	173.5	-65.9	176.1	-18.8	0	0	111.2	V26 E87 T95 D134 F136 T137	V26-Q91 HydrophobicContact CG1-CB 4.13Å; V26-Q91 HydrophobicContact CG2-CB 4.14Å; E87-Q91 VanDerWaalsContact O-CG 3.29Å; E87-Q91 WeakPolarHBondContact O-CG 3.48Å; E87-Q91 PolarHBondContact O-N 2.95Å; Q91-T95 WeakPolarHBondContact O-CB 3.41Å; Q91-T95 PolarHBondContact O-N 3.22Å; Q91-T95 PolarHBondContact O-OG1 2.94Å; Q91-D134 PolarHBondContact NE2-OD1 3.12Å; Q91-D134 PolarHBondContact NE2-OD2 3.31Å; Q91-F136 HydrophobicContact CB-CD1 3.87Å; Q91-F136 HydrophobicContact CB-CE1 3.94Å; Q91-F136 HydrophobicContact CG-CD1 3.75Å; Q91-F136 HydrophobicContact CG-CE1 4.36Å; Q91-T137 WeakPolarHBondContact CG-OG1 3.24Å
92	Y	94.7	Very high	92.5	Very high	33 Å²	33	37.8 Å²	37.8	13%	0.129	19%	0.191	C	C	.	.	H	α-helix	trans	-63	-45.9	177.5	-171.7	-97.5	0	0	0	112	V26 N29 V31 W33 E54 Q88 T89 V90 T95 M96	V26-Y92 VanDerWaalsContact CG1-CA 3.46Å; V26-Y92 HydrophobicContact CG1-CD2 4.13Å; V26-Y92 WeakPolarHBondContact O-CD2 3.33Å; N29-Y92 WeakPolarHBondContact O-CE2 3.45Å; V31-Y92 HydrophobicContact CG2-CD1 3.57Å; V31-Y92 HydrophobicContact CG2-CD2 4.31Å; V31-Y92 HydrophobicContact CG2-CE1 4.13Å; V31-Y92 HydrophobicContact CG2-CG 3.7Å; W33-Y92 HydrophobicContact CH2-CD1 4.49Å; W33-Y92 HydrophobicContact CZ2-CD1 4.02Å; W33-Y92 HydrophobicContact CZ2-CE1 4.09Å; E54-Y92 WeakPolarHBondContact OE1-CE1 3.34Å; E54-Y92 PolarHBondContact OE1-OH 3.06Å; Q88-Y92 WeakPolarHBondContact O-CB 3.41Å; Q88-Y92 PolarHBondContact O-N 3.24Å; Q88-Y92 VanDerWaalsContact O-N 3.17Å; T89-Y92 WeakPolarHBondContact O-CB 3.47Å; T89-Y92 PolarHBondContact O-N 3.11Å; V90-Y92 VanDerWaalsContact C-N 3.29Å; V90-Y92 PolarHBondContact O-N 2.74Å; Y92-T95 PolarHBondContact O-N 3.5Å; Y92-M96 HydrophobicContact CD1-CE 3.41Å; Y92-M96 VanDerWaalsContact CD1-CE 3.41Å; Y92-M96 HydrophobicContact CD1-CG 4.33Å; Y92-M96 HydrophobicContact CD1-SD 4.01Å; Y92-M96 HydrophobicContact CE1-CE 3.41Å; Y92-M96 VanDerWaalsContact CE1-CE 3.41Å; Y92-M96 HydrophobicContact CE1-CG 3.97Å; Y92-M96 HydrophobicContact CE1-SD 3.4Å; Y92-M96 WeakPolarHBondContact CE1-SD 3.33Å; Y92-M96 WeakPolarHBondContact O-CG 2.96Å; Y92-M96 PolarHBondContact O-N 3.4Å
93	I	94.8	Very high	92.5	Very high	0 Å²	0	37.8 Å²	37.8	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-59.9	-49.9	176.8	-66.9	155.8	0	0	0	111.3	W33 F77 L80 M81 I84 T89 V90 T95 M96 V97	W33-I93 HydrophobicContact CH2-CD1 4.26Å; W33-I93 HydrophobicContact CH2-CG1 3.88Å; W33-I93 HydrophobicContact CZ3-CD1 4.48Å; F77-I93 HydrophobicContact CD1-CG2 3.93Å; L80-I93 HydrophobicContact CB-CD1 3.61Å; L80-I93 HydrophobicContact CB-CG1 4.27Å; L80-I93 HydrophobicContact CD1-CG1 4.46Å; M81-I93 HydrophobicContact CG-CB 4.43Å; M81-I93 HydrophobicContact CG-CG2 3.49Å; M81-I93 VanDerWaalsContact CG-CG2 3.49Å; M81-I93 HydrophobicContact SD-CG2 4.32Å; I84-I93 HydrophobicContact CD1-CD1 4.15Å; T89-I93 HydrophobicContact CG2-CD1 3.84Å; T89-I93 HydrophobicContact CG2-CG1 4.44Å; T89-I93 VanDerWaalsContact O-CD1 3.31Å; T89-I93 WeakPolarHBondContact O-CD1 3.29Å; T89-I93 WeakPolarHBondContact O-CG1 3.35Å; T89-I93 PolarHBondContact O-N 3.37Å; V90-I93 PolarHBondContact O-N 2.95Å; I93-T95 VanDerWaalsContact C-N 3.28Å; I93-T95 PolarHBondContact O-N 3.35Å; I93-M96 HydrophobicContact CG1-CE 4.23Å; I93-M96 PolarHBondContact O-N 2.89Å; I93-V97 WeakPolarHBondContact O-CG2 3.2Å; I93-V97 PolarHBondContact O-N 2.83Å
94	L	94.9	Very high	92.5	Very high	0 Å²	0	35.1 Å²	35.1	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-62.2	-37.6	178.6	-70.3	172.4	0	0	0	111.6	M81 V90 V97 D98 T137 M140 A141 I144	M81-L94 HydrophobicContact SD-CD2 3.48Å; M81-L94 WeakPolarHBondContact SD-CD2 3.43Å; M81-L94 HydrophobicContact SD-CG 4.37Å; V90-L94 HydrophobicContact CG1-CD1 4.05Å; V90-L94 HydrophobicContact CG1-CG 4.37Å; V90-L94 WeakPolarHBondContact O-CG 3.37Å; V90-L94 PolarHBondContact O-N 3.26Å; L94-V97 PolarHBondContact O-N 3.39Å; L94-D98 WeakPolarHBondContact O-CB 3.41Å; L94-D98 PolarHBondContact O-N 3.07Å; L94-T137 HydrophobicContact CD1-CG2 3.52Å; L94-M140 HydrophobicContact CB-CB 4.29Å; L94-M140 HydrophobicContact CB-CG 3.77Å; L94-A141 HydrophobicContact CD1-CB 4.45Å; L94-A141 HydrophobicContact CD2-CB 4.47Å; L94-I144 HydrophobicContact CB-CD1 4.22Å; L94-I144 HydrophobicContact CD2-CD1 3.78Å; L94-I144 WeakPolarHBondContact O-CD1 3.28Å
95	T	94.3	Very high	92.6	Very high	2 Å²	2	39.1 Å²	39.1	1%	0.012	19%	0.193	C	C	.	.	H	α-helix	trans	-64.3	-43.8	175.7	-55	0	0	0	0	111.3	A23 R27 Q91 Y92 I93 V97 D98 D99	A23-T95 HydrophobicContact CB-CG2 4.02Å; R27-T95 HydrophobicContact CG-CG2 3.95Å; Q91-T95 WeakPolarHBondContact O-CB 3.41Å; Q91-T95 PolarHBondContact O-N 3.22Å; Q91-T95 PolarHBondContact O-OG1 2.94Å; Y92-T95 PolarHBondContact O-N 3.5Å; I93-T95 VanDerWaalsContact C-N 3.28Å; I93-T95 PolarHBondContact O-N 3.35Å; T95-V97 VanDerWaalsContact C-N 3.33Å; T95-V97 PolarHBondContact O-N 3.42Å; T95-D98 PolarHBondContact O-N 2.95Å; T95-D99 WeakPolarHBondContact O-CB 3.3Å; T95-D99 VanDerWaalsContact O-CG 3.28Å; T95-D99 PolarHBondContact O-N 3.44Å
96	M	93.4	Very high	92.8	Very high	20 Å²	20	41.6 Å²	41.6	10%	0.099	20%	0.196	C	C	.	.	H	α-helix	trans	-61.1	-40.2	174.8	-73.5	-170.9	-69.4	0	0	112.7	W33 I50 E54 F77 Y92 I93 M100	W33-M96 HydrophobicContact CH2-CE 4.36Å; W33-M96 HydrophobicContact CZ2-CE 4.09Å; I50-M96 HydrophobicContact CD1-CE 3.79Å; I50-M96 HydrophobicContact CD1-SD 4.14Å; I50-M96 HydrophobicContact CG1-CE 4.37Å; E54-M96 HydrophobicContact CG-SD 4.29Å; F77-M96 HydrophobicContact CE1-CB 4.12Å; F77-M96 HydrophobicContact CE1-CE 4Å; F77-M96 HydrophobicContact CE1-SD 4.49Å; F77-M96 HydrophobicContact CZ-CB 4.31Å; Y92-M96 HydrophobicContact CD1-CE 3.41Å; Y92-M96 VanDerWaalsContact CD1-CE 3.41Å; Y92-M96 HydrophobicContact CD1-CG 4.33Å; Y92-M96 HydrophobicContact CD1-SD 4.01Å; Y92-M96 HydrophobicContact CE1-CE 3.41Å; Y92-M96 VanDerWaalsContact CE1-CE 3.41Å; Y92-M96 HydrophobicContact CE1-CG 3.97Å; Y92-M96 HydrophobicContact CE1-SD 3.4Å; Y92-M96 WeakPolarHBondContact CE1-SD 3.33Å; Y92-M96 WeakPolarHBondContact O-CG 2.96Å; Y92-M96 PolarHBondContact O-N 3.4Å; I93-M96 HydrophobicContact CG1-CE 4.23Å; I93-M96 PolarHBondContact O-N 2.89Å; M96-M100 VanDerWaalsContact O-CB 3.24Å; M96-M100 WeakPolarHBondContact O-CB 3.31Å; M96-M100 PolarHBondContact O-N 3.1Å
97	V	95.3	Very high	92.9	Very high	0 Å²	0	36.8 Å²	36.8	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-65.6	-46.1	175.6	174.3	0	0	0	0	110.5	F77 I93 L94 T95 D99 M100 L101 F111 F126 I144	F77-V97 HydrophobicContact CB-CG2 4.03Å; F77-V97 HydrophobicContact CD1-CG2 3.78Å; F77-V97 HydrophobicContact CD2-CG2 4Å; F77-V97 HydrophobicContact CE1-CG2 4.18Å; F77-V97 HydrophobicContact CE2-CG2 4.37Å; F77-V97 HydrophobicContact CG-CG2 3.68Å; F77-V97 HydrophobicContact CZ-CG2 4.46Å; I93-V97 WeakPolarHBondContact O-CG2 3.2Å; I93-V97 PolarHBondContact O-N 2.83Å; L94-V97 PolarHBondContact O-N 3.39Å; T95-V97 VanDerWaalsContact C-N 3.33Å; T95-V97 PolarHBondContact O-N 3.42Å; V97-D99 PolarHBondContact O-N 3.08Å; V97-M100 PolarHBondContact O-N 3.3Å; V97-L101 HydrophobicContact CG1-CD1 4.15Å; V97-L101 HydrophobicContact CG1-CG 4.44Å; V97-L101 VanDerWaalsContact O-CG 3.28Å; V97-L101 WeakPolarHBondContact O-CG 3.43Å; V97-L101 PolarHBondContact O-N 3.25Å; V97-F111 HydrophobicContact CG1-CE2 4.09Å; V97-F111 HydrophobicContact CG1-CZ 3.86Å; V97-F111 HydrophobicContact CG2-CZ 4.35Å; V97-F126 HydrophobicContact CG1-CE1 4.36Å; V97-I144 HydrophobicContact CB-CD1 4.06Å; V97-I144 HydrophobicContact CG1-CD1 3.9Å; V97-I144 HydrophobicContact CG1-CG1 4.27Å; V97-I144 HydrophobicContact CG1-CG2 4.03Å
98	D	94.2	Very high	93.1	Very high	12 Å²	12	34.2 Å²	34.2	6%	0.064	16%	0.162	C	C	.	.	H	α-helix	trans	-60.8	-43.8	179	-164.8	63.6	0	0	0	112	L94 T95 L101 Q102 M140 R143 I144 K147	L94-D98 WeakPolarHBondContact O-CB 3.41Å; L94-D98 PolarHBondContact O-N 3.07Å; T95-D98 PolarHBondContact O-N 2.95Å; D98-L101 PolarHBondContact O-N 3.09Å; D98-Q102 VanDerWaalsContact O-CB 3.3Å; D98-Q102 WeakPolarHBondContact O-CB 3.48Å; D98-Q102 PolarHBondContact O-N 3.15Å; D98-M140 HydrophobicContact CB-CG 4.42Å; D98-M140 HydrophobicContact CB-SD 3.57Å; D98-M140 VanDerWaalsContact CB-SD 3.57Å; D98-M140 VanDerWaalsContact CG-SD 3.58Å; D98-R143 IonicContact OD2-NE 2.69Å; D98-R143 IonicContact OD2-NH2 3.91Å; D98-I144 HydrophobicContact CB-CD1 4.38Å; D98-I144 HydrophobicContact CB-CG1 4.12Å; D98-K147 PolarHBondContact O-NZ 3.47Å; D98-K147 VanDerWaalsContact O-NZ 3.16Å; D98-K147 WeakPolarHBondContact OD1-CD 3.36Å; D98-K147 VanDerWaalsContact OD1-CE 3.28Å; D98-K147 WeakPolarHBondContact OD1-CE 3.37Å; D98-K147 IonicContact OD1-NZ 2.77Å; D98-K147 PolarHBondContact OD1-NZ 3.48Å; D98-K147 IonicContact OD2-NZ 3.3Å; D98-K147 PolarHBondContact OD2-NZ 3.35Å; D98-K147 VanDerWaalsContact OD2-NZ 3.08Å
99	D	91.5	Very high	93.2	Very high	53 Å²	53	31 Å²	31	28%	0.283	15%	0.152	S	C	.	.	H	α-helix	trans	-63.3	-48	176.5	-73.5	-17.3	0	0	0	110.9	T95 V97 L101 Q102 E103	T95-D99 WeakPolarHBondContact O-CB 3.3Å; T95-D99 VanDerWaalsContact O-CG 3.28Å; T95-D99 PolarHBondContact O-N 3.44Å; V97-D99 PolarHBondContact O-N 3.08Å; D99-L101 VanDerWaalsContact C-N 3.27Å; D99-L101 PolarHBondContact O-N 3.3Å; D99-Q102 PolarHBondContact O-N 2.83Å; D99-Q102 VanDerWaalsContact O-N 3.1Å; D99-E103 WeakPolarHBondContact O-CG 3.46Å; D99-E103 PolarHBondContact O-N 3.41Å
100	M	93.1	Very high	93.3	Very high	1 Å²	1	31.7 Å²	31.7	1%	0.005	16%	0.156	C	C	.	.	H	α-helix	trans	-56.3	-43.7	177.8	179.7	-172.1	74.3	0	0	111.4	F53 L66 F77 M96 V97 R107 F111	F53-M100 HydrophobicContact CZ-CB 4.49Å; F53-M100 HydrophobicContact CZ-CG 4.39Å; F53-M100 HydrophobicContact CZ-SD 4.32Å; L66-M100 HydrophobicContact CD1-CG 3.9Å; L66-M100 HydrophobicContact CD1-SD 3.86Å; L66-M100 HydrophobicContact CD2-SD 3.89Å; F77-M100 HydrophobicContact CE2-CE 4.49Å; F77-M100 HydrophobicContact CE2-SD 4.06Å; M96-M100 VanDerWaalsContact O-CB 3.24Å; M96-M100 WeakPolarHBondContact O-CB 3.31Å; M96-M100 PolarHBondContact O-N 3.1Å; V97-M100 PolarHBondContact O-N 3.3Å; M100-R107 WeakPolarHBondContact O-CD 3.37Å; M100-R107 PolarHBondContact O-NH1 3.45Å; M100-F111 HydrophobicContact CE-CE2 3.42Å; M100-F111 VanDerWaalsContact CE-CE2 3.42Å; M100-F111 HydrophobicContact CE-CZ 3.72Å
101	L	93	Very high	93.3	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-72.4	-33.7	178.5	-65.8	-177.1	0	0	0	112.3	V97 D98 D99 N104 H105 R107 V108 F111 I144 K147 L148 W151	V97-L101 HydrophobicContact CG1-CD1 4.15Å; V97-L101 HydrophobicContact CG1-CG 4.44Å; V97-L101 VanDerWaalsContact O-CG 3.28Å; V97-L101 WeakPolarHBondContact O-CG 3.43Å; V97-L101 PolarHBondContact O-N 3.25Å; D98-L101 PolarHBondContact O-N 3.09Å; D99-L101 VanDerWaalsContact C-N 3.27Å; D99-L101 PolarHBondContact O-N 3.3Å; L101-N104 CarbonylContact O-C 3.6Å; L101-N104 VanDerWaalsContact O-C 3.27Å; L101-H105 PolarHBondContact O-N 3.11Å; L101-R107 HydrophobicContact CD2-CB 4.14Å; L101-V108 HydrophobicContact CD1-CG1 4.32Å; L101-V108 HydrophobicContact CD2-CB 4.37Å; L101-V108 HydrophobicContact CD2-CG1 3.71Å; L101-V108 HydrophobicContact CG-CG1 4.48Å; L101-F111 HydrophobicContact CD2-CD2 4.43Å; L101-F111 HydrophobicContact CD2-CE2 4.09Å; L101-I144 HydrophobicContact CD1-CG2 4.02Å; L101-K147 HydrophobicContact CB-CD 4.34Å; L101-K147 HydrophobicContact CD1-CB 4.49Å; L101-L148 HydrophobicContact CD1-CD2 4.32Å; L101-W151 HydrophobicContact CB-CZ3 4.16Å; L101-W151 WeakPolarHBondContact O-CZ3 3.31Å
102	Q	90.5	Very high	93.3	Very high	85 Å²	85	30.7 Å²	30.7	40%	0.397	15%	0.151	S	C	.	.	H	α-helix	trans	-69.6	-38.2	177.7	-168.4	65.3	38.2	0	0	112.1	D98 D99 N104	D98-Q102 VanDerWaalsContact O-CB 3.3Å; D98-Q102 WeakPolarHBondContact O-CB 3.48Å; D98-Q102 PolarHBondContact O-N 3.15Å; D99-Q102 PolarHBondContact O-N 2.83Å; D99-Q102 VanDerWaalsContact O-N 3.1Å; Q102-N104 VanDerWaalsContact C-N 3.3Å; Q102-N104 PolarHBondContact O-N 3.25Å
103	E	90.6	Very high	93.2	Very high	83 Å²	83	32.7 Å²	32.7	39%	0.388	16%	0.164	S	C	.	.	H	α-helix	trans	-61.5	-37	177.1	-76.4	175.6	-166.8	0	0	112	K62 D99 R107	K62-E103 IonicContact NZ-OE1 3.49Å; K62-E103 PolarHBondContact NZ-OE1 3.07Å; K62-E103 VanDerWaalsContact NZ-OE1 3.09Å; D99-E103 WeakPolarHBondContact O-CG 3.46Å; D99-E103 PolarHBondContact O-N 3.41Å; E103-R107 VanDerWaalsContact CB-NH1 3.33Å; E103-R107 IonicContact OE2-CZ 3.09Å; E103-R107 IonicContact OE2-NH1 2.67Å; E103-R107 PolarHBondContact OE2-NH1 2.79Å; E103-R107 IonicContact OE2-NH2 3.39Å
104	N	90.4	Very high	93.2	Very high	42 Å²	42	34.8 Å²	34.8	23%	0.225	17%	0.172	C	C	.	.			trans	-153	111.6	175.9	179.4	-7	0	0	0	111.2	Q63 L101 Q102 Q106 R107	Q63-N104 PolarHBondContact OE1-ND2 2.8Å; L101-N104 CarbonylContact O-C 3.6Å; L101-N104 VanDerWaalsContact O-C 3.27Å; Q102-N104 VanDerWaalsContact C-N 3.3Å; Q102-N104 PolarHBondContact O-N 3.25Å; N104-Q106 PolarHBondContact O-N 3.49Å; N104-Q106 VanDerWaalsContact O-N 3.08Å; N104-Q106 WeakPolarHBondContact OD1-CB 3.42Å; N104-Q106 PolarHBondContact OD1-N 2.88Å; N104-R107 HydrophobicContact CB-CG 4.01Å; N104-R107 VanDerWaalsContact O-CB 3.31Å; N104-R107 WeakPolarHBondContact O-CB 3.37Å; N104-R107 WeakPolarHBondContact O-CG 3.23Å; N104-R107 PolarHBondContact O-N 3.4Å
105	H	92.4	Very high	93	Very high	85 Å²	85	34.8 Å²	34.8	39%	0.394	17%	0.172	S	C	.	.	G	3₁₀ helix	trans	-58.9	-25	-178.1	-58.1	166.6	0	0	0	113.6	L101 R107 V108 W151	L101-H105 PolarHBondContact O-N 3.11Å; H105-R107 PolarHBondContact O-N 3.13Å; H105-V108 WeakPolarHBondContact O-CG2 3.38Å; H105-V108 PolarHBondContact O-N 3.23Å; H105-W151 HydrophobicContact CB-CB 4.3Å; H105-W151 HydrophobicContact CB-CD2 3.85Å; H105-W151 HydrophobicContact CB-CE3 3.92Å; H105-W151 HydrophobicContact CB-CG 4.03Å; H105-W151 HydrophobicContact CB-CZ3 4.48Å; H105-W151 AromaticContact CD2-CD2 3.9Å; H105-W151 AromaticContact CD2-CE2 3.78Å; H105-W151 AromaticContact CD2-CE3 3.74Å; H105-W151 AromaticContact CD2-CH2 3.32Å; H105-W151 WeakPolarHBondContact CD2-CH2 3.44Å; H105-W151 AromaticContact CD2-CZ2 3.53Å; H105-W151 AromaticContact CD2-CZ3 3.44Å; H105-W151 VanDerWaalsContact CD2-CZ3 3.44Å; H105-W151 WeakPolarHBondContact CD2-CZ3 3.5Å; H105-W151 AromaticContact CE1-CZ2 3.84Å; H105-W151 AromaticContact CG-CD2 3.75Å; H105-W151 AromaticContact CG-CE2 3.81Å; H105-W151 AromaticContact CG-CE3 3.91Å; H105-W151 AromaticContact ND1-CE2 3.95Å; H105-W151 AromaticContact NE2-CE2 3.92Å; H105-W151 AromaticContact NE2-CH2 3.47Å; H105-W151 WeakPolarHBondContact NE2-CH2 3.21Å; H105-W151 AromaticContact NE2-CZ2 3.4Å; H105-W151 WeakPolarHBondContact NE2-CZ2 3.43Å
106	Q	91.4	Very high	92.9	Very high	148 Å²	148	41.4 Å²	41.4	69%	0.692	20%	0.197	S	C	*	.	G	3₁₀ helix	trans	-68.4	-20.8	178.6	-60.4	-177	3.9	0	0	112.6	N104 V108 S109	N104-Q106 PolarHBondContact O-N 3.49Å; N104-Q106 VanDerWaalsContact O-N 3.08Å; N104-Q106 WeakPolarHBondContact OD1-CB 3.42Å; N104-Q106 PolarHBondContact OD1-N 2.88Å; Q106-V108 PolarHBondContact O-N 3.49Å; Q106-V108 VanDerWaalsContact O-N 3.13Å; Q106-S109 WeakPolarHBondContact O-CB 3.31Å; Q106-S109 PolarHBondContact O-N 3.36Å; Q106-S109 PolarHBondContact O-OG 3.42Å
107	R	93.9	Very high	92.7	Very high	10 Å²	10	50 Å²	50	4%	0.038	23%	0.228	C	C	.	.	G	3₁₀ helix	trans	-66.4	-13	-179	-67.1	170.8	179.1	174.9	-0.3	113.6	Q63 L66 M100 L101 E103 N104 H105 S109 I110	Q63-R107 VanDerWaalsContact OE1-NE 3.07Å; L66-R107 HydrophobicContact CD1-CG 4.37Å; M100-R107 WeakPolarHBondContact O-CD 3.37Å; M100-R107 PolarHBondContact O-NH1 3.45Å; L101-R107 HydrophobicContact CD2-CB 4.14Å; E103-R107 VanDerWaalsContact CB-NH1 3.33Å; E103-R107 IonicContact OE2-CZ 3.09Å; E103-R107 IonicContact OE2-NH1 2.67Å; E103-R107 PolarHBondContact OE2-NH1 2.79Å; E103-R107 IonicContact OE2-NH2 3.39Å; N104-R107 HydrophobicContact CB-CG 4.01Å; N104-R107 VanDerWaalsContact O-CB 3.31Å; N104-R107 WeakPolarHBondContact O-CB 3.37Å; N104-R107 WeakPolarHBondContact O-CG 3.23Å; N104-R107 PolarHBondContact O-N 3.4Å; H105-R107 PolarHBondContact O-N 3.13Å; R107-S109 PolarHBondContact O-N 3.03Å; R107-I110 HydrophobicContact CB-CD1 4.03Å; R107-I110 HydrophobicContact CG-CD1 4.23Å; R107-I110 VanDerWaalsContact O-CB 3.27Å; R107-I110 WeakPolarHBondContact O-CB 3.28Å; R107-I110 VanDerWaalsContact O-CG1 3.31Å; R107-I110 WeakPolarHBondContact O-CG1 3.42Å; R107-I110 PolarHBondContact O-N 3.37Å; R107-I110 VanDerWaalsContact O-N 3.13Å
108	V	93.9	Very high	92.3	Very high	4 Å²	4	52.7 Å²	52.7	2%	0.024	25%	0.247	C	C	.	.	H	α-helix	trans	-55.8	-30.8	168.3	-61.5	0	0	0	0	112	L101 H105 Q106 I110 F111 F112 L148 W151	L101-V108 HydrophobicContact CD1-CG1 4.32Å; L101-V108 HydrophobicContact CD2-CB 4.37Å; L101-V108 HydrophobicContact CD2-CG1 3.71Å; L101-V108 HydrophobicContact CG-CG1 4.48Å; H105-V108 WeakPolarHBondContact O-CG2 3.38Å; H105-V108 PolarHBondContact O-N 3.23Å; Q106-V108 PolarHBondContact O-N 3.49Å; Q106-V108 VanDerWaalsContact O-N 3.13Å; V108-I110 PolarHBondContact O-N 2.93Å; V108-I110 VanDerWaalsContact O-N 3.16Å; V108-F111 PolarHBondContact O-N 2.86Å; V108-F112 HydrophobicContact CB-CE2 4.31Å; V108-F112 WeakPolarHBondContact O-CD2 3.34Å; V108-L148 HydrophobicContact CB-CD2 3.9Å; V108-L148 HydrophobicContact CG1-CD2 4.01Å; V108-W151 HydrophobicContact CG1-CB 4.02Å; V108-W151 HydrophobicContact CG1-CE3 3.96Å; V108-W151 HydrophobicContact CG2-CB 4.05Å; V108-W151 WeakPolarHBondContact CG2-O 3.39Å
109	S	93.4	Very high	92	Very high	43 Å²	43	62 Å²	62	30%	0.301	29%	0.287	S	S	.	.	H	α-helix	trans	-60.8	-27.2	180	76.4	0	0	0	0	112.5	Q106 R107 F111 F112 D113	Q106-S109 WeakPolarHBondContact O-CB 3.31Å; Q106-S109 PolarHBondContact O-N 3.36Å; Q106-S109 PolarHBondContact O-OG 3.42Å; R107-S109 PolarHBondContact O-N 3.03Å; S109-F111 VanDerWaalsContact C-N 3.3Å; S109-F111 PolarHBondContact O-N 3.1Å; S109-F112 PolarHBondContact O-N 3.26Å; S109-D113 WeakPolarHBondContact O-CB 3.47Å; S109-D113 PolarHBondContact O-N 3Å
110	I	94.8	Very high	91.9	Very high	18 Å²	18	62.9 Å²	62.9	9%	0.092	29%	0.292	C	S	.	.	H	α-helix	trans	-58.4	-43.7	179.5	-60.5	175.6	0	0	0	110.8	L66 G70 C73 A74 R107 V108 Y114	L66-I110 HydrophobicContact CB-CD1 4.06Å; L66-I110 HydrophobicContact CD2-CD1 4.15Å; L66-I110 HydrophobicContact CG-CD1 4.47Å; G70-I110 WeakPolarHBondContact O-CG2 3.4Å; C73-I110 HydrophobicContact CB-CG2 4.46Å; A74-I110 HydrophobicContact CB-CG2 4.06Å; R107-I110 HydrophobicContact CB-CD1 4.03Å; R107-I110 HydrophobicContact CG-CD1 4.23Å; R107-I110 VanDerWaalsContact O-CB 3.27Å; R107-I110 WeakPolarHBondContact O-CB 3.28Å; R107-I110 VanDerWaalsContact O-CG1 3.31Å; R107-I110 WeakPolarHBondContact O-CG1 3.42Å; R107-I110 PolarHBondContact O-N 3.37Å; R107-I110 VanDerWaalsContact O-N 3.13Å; V108-I110 PolarHBondContact O-N 2.93Å; V108-I110 VanDerWaalsContact O-N 3.16Å; I110-Y114 WeakPolarHBondContact O-CB 3.09Å; I110-Y114 PolarHBondContact O-N 2.9Å; I110-Y114 VanDerWaalsContact O-N 3.13Å
111	F	95.4	Very high	91.7	Very high	0 Å²	0	65.2 Å²	65.2	0%	0	31%	0.306	C	S	.	.	H	α-helix	trans	-72.1	-38.5	178.9	-65.4	-75.4	0	0	0	112.2	A74 F77 I78 V97 M100 L101 V108 S109 A115 F126 L148	A74-F111 HydrophobicContact CB-CD1 3.87Å; A74-F111 HydrophobicContact CB-CE1 4.22Å; F77-F111 HydrophobicContact CB-CE1 4.33Å; F77-F111 HydrophobicContact CD2-CZ 4.34Å; I78-F111 HydrophobicContact CD1-CD1 4.32Å; V97-F111 HydrophobicContact CG1-CE2 4.09Å; V97-F111 HydrophobicContact CG1-CZ 3.86Å; V97-F111 HydrophobicContact CG2-CZ 4.35Å; M100-F111 HydrophobicContact CE-CE2 3.42Å; M100-F111 VanDerWaalsContact CE-CE2 3.42Å; M100-F111 HydrophobicContact CE-CZ 3.72Å; L101-F111 HydrophobicContact CD2-CD2 4.43Å; L101-F111 HydrophobicContact CD2-CE2 4.09Å; V108-F111 PolarHBondContact O-N 2.86Å; S109-F111 VanDerWaalsContact C-N 3.3Å; S109-F111 PolarHBondContact O-N 3.1Å; F111-A115 WeakPolarHBondContact O-CB 3.44Å; F111-A115 PolarHBondContact O-N 3.4Å; F111-F126 HydrophobicContact CD1-CE2 4.21Å; F111-F126 AromaticContact CD1-CZ 3.9Å; F111-F126 HydrophobicContact CD1-CZ 3.9Å; F111-F126 AromaticContact CE1-CZ 3.9Å; F111-F126 HydrophobicContact CE1-CZ 3.9Å; F111-F126 HydrophobicContact CG-CE2 4.41Å; F111-F126 HydrophobicContact CG-CZ 4.28Å; F111-F126 HydrophobicContact CZ-CZ 4.27Å; F111-L148 HydrophobicContact CB-CD2 4.3Å; F111-L148 HydrophobicContact CD2-CD2 4.02Å; F111-L148 HydrophobicContact CG-CD2 4.48Å
112	F	93.9	Very high	91.7	Very high	6 Å²	6	65.2 Å²	65.2	3%	0.026	31%	0.306	C	S	.	.	H	α-helix	trans	-67.4	-44.1	176	-69.6	-73.2	0	0	0	112.3	V108 S109 Y114 A115 R116 A122 W123 L148 E154	V108-F112 HydrophobicContact CB-CE2 4.31Å; V108-F112 WeakPolarHBondContact O-CD2 3.34Å; S109-F112 PolarHBondContact O-N 3.26Å; F112-Y114 VanDerWaalsContact C-N 3.29Å; F112-Y114 PolarHBondContact O-N 3.42Å; F112-A115 PolarHBondContact O-N 3.21Å; F112-R116 VanDerWaalsContact O-CB 3.31Å; F112-R116 WeakPolarHBondContact O-CB 3.41Å; F112-R116 PolarHBondContact O-N 2.78Å; F112-A122 HydrophobicContact CD1-CB 3.79Å; F112-A122 HydrophobicContact CE1-CB 3.8Å; F112-A122 HydrophobicContact CG-CB 4.42Å; F112-A122 HydrophobicContact CZ-CB 4.42Å; F112-W123 AromaticContact CE1-CH2 3.72Å; F112-W123 HydrophobicContact CE1-CH2 3.72Å; F112-W123 AromaticContact CE1-CZ2 3.69Å; F112-W123 HydrophobicContact CE1-CZ2 3.69Å; F112-W123 HydrophobicContact CE1-CZ3 4.38Å; F112-W123 AromaticContact CZ-CH2 3.47Å; F112-W123 HydrophobicContact CZ-CH2 3.47Å; F112-W123 VanDerWaalsContact CZ-CH2 3.47Å; F112-W123 AromaticContact CZ-CZ2 3.93Å; F112-W123 HydrophobicContact CZ-CZ2 3.93Å; F112-W123 HydrophobicContact CZ-CZ3 4.06Å; F112-L148 HydrophobicContact CE2-CB 4.43Å; F112-L148 HydrophobicContact CE2-CD2 4.23Å; F112-L148 HydrophobicContact CZ-CB 4.27Å; F112-L148 WeakPolarHBondContact CZ-O 3.18Å; F112-E154 HydrophobicContact CD1-CB 3.89Å; F112-E154 HydrophobicContact CD1-CG 4.08Å; F112-E154 WeakPolarHBondContact CD1-OE2 3.39Å; F112-E154 HydrophobicContact CE1-CB 3.82Å
113	D	92.8	Very high	91.9	Very high	74 Å²	74	61.4 Å²	61.4	40%	0.396	29%	0.288	S	S	.	.	H	α-helix	trans	-64.1	-37.3	178.8	-69.3	-28.4	0	0	0	111	S109 R116 R117	S109-D113 WeakPolarHBondContact O-CB 3.47Å; S109-D113 PolarHBondContact O-N 3Å; D113-R116 IonicContact OD1-NH1 3.6Å; D113-R117 WeakPolarHBondContact O-CG 3.3Å; D113-R117 PolarHBondContact O-N 2.75Å
114	Y	93.3	Very high	91.9	Very high	45 Å²	45	59.9 Å²	59.9	18%	0.176	29%	0.285	C	S	.	.	H	α-helix	trans	-66.4	-47.2	172.7	177.7	-98.3	0	0	0	112.6	S71 A74 K75 I78 I110 F112 R116 R117 S118	S71-Y114 WeakPolarHBondContact O-CD2 3.24Å; A74-Y114 HydrophobicContact CB-CD1 4.02Å; A74-Y114 HydrophobicContact CB-CD2 4.18Å; A74-Y114 HydrophobicContact CB-CG 3.62Å; K75-Y114 HydrophobicContact CB-CD2 4.35Å; K75-Y114 HydrophobicContact CB-CE2 3.58Å; K75-Y114 HydrophobicContact CG-CE2 4.21Å; I78-Y114 HydrophobicContact CD1-CD1 3.57Å; I78-Y114 HydrophobicContact CD1-CE1 3.58Å; I110-Y114 WeakPolarHBondContact O-CB 3.09Å; I110-Y114 PolarHBondContact O-N 2.9Å; I110-Y114 VanDerWaalsContact O-N 3.13Å; F112-Y114 VanDerWaalsContact C-N 3.29Å; F112-Y114 PolarHBondContact O-N 3.42Å; Y114-R116 VanDerWaalsContact C-N 3.31Å; Y114-R116 PolarHBondContact O-N 3.22Å; Y114-R117 PolarHBondContact O-N 3.2Å; Y114-S118 PolarHBondContact O-N 3.34Å; Y114-S118 PolarHBondContact O-OG 2.95Å
115	A	92.1	Very high	92.1	Very high	0 Å²	0	59.8 Å²	59.8	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-60.3	-41.9	177.1	0	0	0	0	0	111.7	F111 F112 R117 S118 K119 N120 T121 A122 Y125	F111-A115 WeakPolarHBondContact O-CB 3.44Å; F111-A115 PolarHBondContact O-N 3.4Å; F112-A115 PolarHBondContact O-N 3.21Å; A115-R117 VanDerWaalsContact C-N 3.33Å; A115-R117 PolarHBondContact O-N 2.92Å; A115-S118 WeakPolarHBondContact CA-OG 3.27Å; A115-S118 CarbonylContact O-C 3.27Å; A115-S118 WeakPolarHBondContact O-CA 3.31Å; A115-S118 PolarHBondContact O-N 2.85Å; A115-S118 PolarHBondContact O-OG 3.08Å; A115-K119 PolarHBondContact O-N 3.47Å; A115-N120 CarbonylContact C-O 3.54Å; A115-N120 WeakPolarHBondContact CB-O 3.19Å; A115-N120 PolarHBondContact O-N 3.31Å; A115-T121 VanDerWaalsContact CB-C 3.5Å; A115-A122 HydrophobicContact CB-CB 4.34Å; A115-Y125 HydrophobicContact CB-CE2 3.92Å
116	R	91	Very high	92.2	Very high	141 Å²	141	55.8 Å²	55.8	53%	0.532	26%	0.263	S	S	.	.	H	α-helix	trans	-61.9	-38.6	177.9	-168.4	-179.2	-64.7	158.2	-2.4	112.4	F112 D113 Y114 S118 K119 E154	F112-R116 VanDerWaalsContact O-CB 3.31Å; F112-R116 WeakPolarHBondContact O-CB 3.41Å; F112-R116 PolarHBondContact O-N 2.78Å; D113-R116 IonicContact OD1-NH1 3.6Å; Y114-R116 VanDerWaalsContact C-N 3.31Å; Y114-R116 PolarHBondContact O-N 3.22Å; R116-S118 PolarHBondContact O-N 2.77Å; R116-K119 PolarHBondContact O-N 2.91Å; R116-E154 IonicContact CZ-OE1 3.69Å; R116-E154 IonicContact NE-OE1 3.57Å; R116-E154 PolarHBondContact NE-OE1 3.37Å; R116-E154 IonicContact NH2-OE1 3.01Å; R116-E154 PolarHBondContact NH2-OE1 2.84Å
117	R	90.2	Very high	92.4	Very high	200 Å²	200	49.3 Å²	49.3	76%	0.755	23%	0.233	S	C	*	.	H	α-helix	trans	-62.6	-32.4	174.5	-73	171.6	-173.8	-106.9	2.9	112.5	D113 Y114 A115 K119	D113-R117 WeakPolarHBondContact O-CG 3.3Å; D113-R117 PolarHBondContact O-N 2.75Å; Y114-R117 PolarHBondContact O-N 3.2Å; A115-R117 VanDerWaalsContact C-N 3.33Å; A115-R117 PolarHBondContact O-N 2.92Å; R117-K119 VanDerWaalsContact C-N 3.29Å
118	S	87.3	Confident	92.4	Very high	57 Å²	57	52.1 Å²	52.1	40%	0.399	25%	0.253	S	S	.	.	T	Hydrogen-bonded Turn	trans	-87.7	8.4	175.1	51.6	0	0	0	0	113.7	Y114 A115 R116 N120 Y125	Y114-S118 PolarHBondContact O-N 3.34Å; Y114-S118 PolarHBondContact O-OG 2.95Å; A115-S118 WeakPolarHBondContact CA-OG 3.27Å; A115-S118 CarbonylContact O-C 3.27Å; A115-S118 WeakPolarHBondContact O-CA 3.31Å; A115-S118 PolarHBondContact O-N 2.85Å; A115-S118 PolarHBondContact O-OG 3.08Å; R116-S118 PolarHBondContact O-N 2.77Å; S118-N120 PolarHBondContact O-N 3.42Å; S118-Y125 PolarHBondContact OG-OH 3.28Å
119	K	87.6	Confident	92.5	Very high	207 Å²	207	52.5 Å²	52.5	90%	0.9	26%	0.255	S	S	*	.	T	Hydrogen-bonded Turn	trans	54.4	35.6	-175.4	-58.1	-177.7	178.8	179.8	0	113	A115 R116 R117	A115-K119 PolarHBondContact O-N 3.47Å; R116-K119 PolarHBondContact O-N 2.91Å; R117-K119 VanDerWaalsContact C-N 3.29Å
120	N	88.3	Confident	92.5	Very high	72 Å²	72	50.9 Å²	50.9	39%	0.385	24%	0.242	S	C	.	.	S	Bend	trans	-128.7	170.9	179.6	-154.9	-8.6	0	0	0	110.6	A115 S118	A115-N120 CarbonylContact C-O 3.54Å; A115-N120 WeakPolarHBondContact CB-O 3.19Å; A115-N120 PolarHBondContact O-N 3.31Å; S118-N120 PolarHBondContact O-N 3.42Å
121	T	90.3	Very high	92.4	Very high	49 Å²	49	55.5 Å²	55.5	30%	0.301	27%	0.267	S	S	.	.			trans	-92	165.7	169.6	61.1	0	0	0	0	110.4	A115 W123 P124 Y125	A115-T121 VanDerWaalsContact CB-C 3.5Å; T121-W123 VanDerWaalsContact C-N 3.33Å; T121-P124 WeakPolarHBondContact O-CD 3.34Å; T121-P124 WeakPolarHBondContact OG1-CD 3.16Å; T121-Y125 WeakPolarHBondContact O-CE2 3.43Å
122	A	91.9	Very high	92.3	Very high	0 Å²	0	58.3 Å²	58.3	0%	0	28%	0.278	C	S	.	.	S	Bend	trans	-75.5	-21.8	179.3	0	0	0	0	0	113.1	F112 A115 Y125 F126	F112-A122 HydrophobicContact CD1-CB 3.79Å; F112-A122 HydrophobicContact CE1-CB 3.8Å; F112-A122 HydrophobicContact CG-CB 4.42Å; F112-A122 HydrophobicContact CZ-CB 4.42Å; A115-A122 HydrophobicContact CB-CB 4.34Å; A122-Y125 WeakPolarHBondContact O-CD2 3.31Å; A122-Y125 PolarHBondContact O-N 3.27Å; A122-F126 WeakPolarHBondContact O-CD2 3.44Å
123	W	94.1	Very high	92	Very high	5 Å²	5	67.1 Å²	67.1	2%	0.019	32%	0.319	C	S	.	.	G	3₁₀ helix	trans	-64	-44.3	-170.2	-37.4	123	0	0	0	114.6	F112 T121 Y125 F126 L127 L148 A149 M156 D160	F112-W123 AromaticContact CE1-CH2 3.72Å; F112-W123 HydrophobicContact CE1-CH2 3.72Å; F112-W123 AromaticContact CE1-CZ2 3.69Å; F112-W123 HydrophobicContact CE1-CZ2 3.69Å; F112-W123 HydrophobicContact CE1-CZ3 4.38Å; F112-W123 AromaticContact CZ-CH2 3.47Å; F112-W123 HydrophobicContact CZ-CH2 3.47Å; F112-W123 VanDerWaalsContact CZ-CH2 3.47Å; F112-W123 AromaticContact CZ-CZ2 3.93Å; F112-W123 HydrophobicContact CZ-CZ2 3.93Å; F112-W123 HydrophobicContact CZ-CZ3 4.06Å; T121-W123 VanDerWaalsContact C-N 3.33Å; W123-Y125 PolarHBondContact O-N 3.48Å; W123-F126 PolarHBondContact O-N 2.88Å; W123-L127 HydrophobicContact CB-CD1 3.68Å; W123-L127 HydrophobicContact CB-CG 4.21Å; W123-L127 WeakPolarHBondContact O-CG 3.45Å; W123-L127 PolarHBondContact O-N 3.47Å; W123-L148 HydrophobicContact CH2-CB 4.34Å; W123-L148 HydrophobicContact CZ3-CB 3.66Å; W123-A149 HydrophobicContact CH2-CB 4.08Å; W123-A149 HydrophobicContact CZ3-CB 4.19Å; W123-M156 HydrophobicContact CB-CE 4.4Å; W123-M156 HydrophobicContact CD2-CB 4.23Å; W123-M156 HydrophobicContact CD2-CE 3.57Å; W123-M156 HydrophobicContact CD2-CG 4.14Å; W123-M156 HydrophobicContact CE3-CE 3.29Å; W123-M156 HydrophobicContact CG-CE 4.06Å; W123-M156 HydrophobicContact CG-CG 4.27Å; W123-M156 HydrophobicContact CH2-CB 4.19Å; W123-M156 HydrophobicContact CH2-CE 4.36Å; W123-M156 HydrophobicContact CZ2-CB 3.71Å; W123-M156 HydrophobicContact CZ2-CG 4.49Å; W123-M156 HydrophobicContact CZ3-CE 3.71Å; W123-D160 HydrophobicContact CB-CB 4.41Å
124	P	92.4	Very high	91.9	Very high	51 Å²	51	65.3 Å²	65.3	33%	0.331	31%	0.31	S	S	.	.	G	3₁₀ helix	trans	-60.2	-19.3	-178.5	-26.3	36.5	0	0	0	114.2	T121 P128	T121-P124 WeakPolarHBondContact O-CD 3.34Å; T121-P124 WeakPolarHBondContact OG1-CD 3.16Å; P124-P128 WeakPolarHBondContact O-CD 3.45Å; P124-P128 VanDerWaalsContact O-CG 3.27Å; P124-P128 WeakPolarHBondContact O-CG 3.23Å
125	Y	92.6	Very high	91.7	Very high	41 Å²	41	65.9 Å²	65.9	16%	0.161	32%	0.319	C	S	.	.	G	3₁₀ helix	trans	-75.8	-25.8	176.4	-57.2	-56.6	0	0	0	113.3	I78 A115 S118 T121 A122 W123	I78-Y125 HydrophobicContact CD1-CD1 4.18Å; I78-Y125 HydrophobicContact CD1-CD2 3.68Å; I78-Y125 HydrophobicContact CD1-CE1 4.49Å; I78-Y125 HydrophobicContact CD1-CE2 4.04Å; I78-Y125 HydrophobicContact CD1-CG 3.77Å; I78-Y125 HydrophobicContact CG1-CD1 4.42Å; I78-Y125 HydrophobicContact CG1-CD2 4.47Å; I78-Y125 HydrophobicContact CG1-CG 4.09Å; I78-Y125 HydrophobicContact CG2-CD1 3.47Å; I78-Y125 VanDerWaalsContact CG2-CD1 3.47Å; I78-Y125 HydrophobicContact CG2-CE1 3.95Å; I78-Y125 HydrophobicContact CG2-CG 3.99Å; A115-Y125 HydrophobicContact CB-CE2 3.92Å; S118-Y125 PolarHBondContact OG-OH 3.28Å; T121-Y125 WeakPolarHBondContact O-CE2 3.43Å; A122-Y125 WeakPolarHBondContact O-CD2 3.31Å; A122-Y125 PolarHBondContact O-N 3.27Å; W123-Y125 PolarHBondContact O-N 3.48Å
126	F	95.1	Very high	91.7	Very high	0 Å²	0	66 Å²	66	0%	0	32%	0.319	C	S	.	.	T	Hydrogen-bonded Turn	trans	-112.6	-34.4	-174.8	-62.5	-85.6	0	0	0	113.1	M81 V97 F111 A122 W123 P128 M129 I144 I145 L148	M81-F126 HydrophobicContact CE-CD1 4.09Å; M81-F126 HydrophobicContact CE-CE1 3.58Å; M81-F126 HydrophobicContact CE-CZ 4.06Å; M81-F126 HydrophobicContact SD-CD1 4.36Å; M81-F126 HydrophobicContact SD-CE1 4.1Å; V97-F126 HydrophobicContact CG1-CE1 4.36Å; F111-F126 HydrophobicContact CD1-CE2 4.21Å; F111-F126 AromaticContact CD1-CZ 3.9Å; F111-F126 HydrophobicContact CD1-CZ 3.9Å; F111-F126 AromaticContact CE1-CZ 3.9Å; F111-F126 HydrophobicContact CE1-CZ 3.9Å; F111-F126 HydrophobicContact CG-CE2 4.41Å; F111-F126 HydrophobicContact CG-CZ 4.28Å; F111-F126 HydrophobicContact CZ-CZ 4.27Å; A122-F126 WeakPolarHBondContact O-CD2 3.44Å; W123-F126 PolarHBondContact O-N 2.88Å; F126-P128 VanDerWaalsContact C-CD 3.46Å; F126-M129 VanDerWaalsContact O-CB 3.25Å; F126-M129 WeakPolarHBondContact O-CB 3.17Å; F126-M129 PolarHBondContact O-N 3.44Å; F126-I144 HydrophobicContact CD1-CG2 3.77Å; F126-I144 HydrophobicContact CE1-CG2 3.63Å; F126-I144 HydrophobicContact CG-CG2 4.45Å; F126-I144 HydrophobicContact CZ-CG2 4.22Å; F126-I145 HydrophobicContact CB-CD1 4.05Å; F126-I145 HydrophobicContact CB-CG1 3.59Å; F126-L148 HydrophobicContact CD2-CD1 3.52Å; F126-L148 HydrophobicContact CE2-CD1 3.46Å; F126-L148 VanDerWaalsContact CE2-CD1 3.46Å; F126-L148 HydrophobicContact CG-CD1 4.15Å; F126-L148 HydrophobicContact CZ-CD1 4.03Å
127	L	95.5	Very high	91.8	Very high	12 Å²	12	59.3 Å²	59.3	6%	0.063	29%	0.294	C	S	.	.	G	3₁₀ helix	trans	-56.3	-39.2	-178	-69.1	170.5	0	0	0	114.1	W123 M129 L130 I145 D160 Y163	W123-L127 HydrophobicContact CB-CD1 3.68Å; W123-L127 HydrophobicContact CB-CG 4.21Å; W123-L127 WeakPolarHBondContact O-CG 3.45Å; W123-L127 PolarHBondContact O-N 3.47Å; L127-M129 PolarHBondContact O-N 2.84Å; L127-M129 VanDerWaalsContact O-N 3.14Å; L127-L130 HydrophobicContact CD2-CD1 4.25Å; L127-L130 WeakPolarHBondContact O-CB 3.37Å; L127-L130 PolarHBondContact O-N 2.92Å; L127-L130 VanDerWaalsContact O-N 3.08Å; L127-I145 HydrophobicContact CD2-CD1 3.99Å; L127-I145 HydrophobicContact CD2-CG2 4.41Å; L127-D160 HydrophobicContact CD1-CB 3.85Å; L127-Y163 HydrophobicContact CB-CE1 4.41Å; L127-Y163 HydrophobicContact CD2-CD1 4.03Å; L127-Y163 HydrophobicContact CD2-CE1 4.33Å
128	P	95.1	Very high	92	Very high	70 Å²	70	50.4 Å²	50.4	46%	0.455	26%	0.262	S	S	.	.	G	3₁₀ helix	trans	-59.8	-25.2	176.3	-26.4	36.5	0	0	0	114	P124 F126 L130 N131	P124-P128 WeakPolarHBondContact O-CD 3.45Å; P124-P128 VanDerWaalsContact O-CG 3.27Å; P124-P128 WeakPolarHBondContact O-CG 3.23Å; F126-P128 VanDerWaalsContact C-CD 3.46Å; P128-L130 PolarHBondContact O-N 3.19Å; P128-N131 PolarHBondContact O-N 3.48Å; P128-N131 VanDerWaalsContact O-N 3.12Å
129	M	94.4	Very high	92.2	Very high	12 Å²	12	48.7 Å²	48.7	6%	0.059	25%	0.247	C	C	.	.	G	3₁₀ helix	trans	-66.6	-19.2	178.6	-60	-63.1	150.4	0	0	112.6	M81 F126 L127 N131 R132 A141	M81-M129 HydrophobicContact CB-CE 3.93Å; M81-M129 WeakPolarHBondContact O-CE 3.49Å; F126-M129 VanDerWaalsContact O-CB 3.25Å; F126-M129 WeakPolarHBondContact O-CB 3.17Å; F126-M129 PolarHBondContact O-N 3.44Å; L127-M129 PolarHBondContact O-N 2.84Å; L127-M129 VanDerWaalsContact O-N 3.14Å; M129-N131 PolarHBondContact O-N 2.81Å; M129-R132 WeakPolarHBondContact O-CB 3.49Å; M129-R132 WeakPolarHBondContact O-CG 3.44Å; M129-R132 PolarHBondContact O-N 3.33Å; M129-R132 HydrophobicContact SD-CG 4.33Å; M129-A141 HydrophobicContact CB-CB 3.51Å; M129-A141 HydrophobicContact CG-CB 4.44Å
130	L	94.9	Very high	92.5	Very high	8 Å²	8	39 Å²	39	4%	0.042	21%	0.205	C	C	.	.	G	3₁₀ helix	trans	-69.7	-13.8	174.7	-59.5	-177.1	0	0	0	113.4	L127 P128 V138 A141 A142 I145 Y163 Y164 W167	L127-L130 HydrophobicContact CD2-CD1 4.25Å; L127-L130 WeakPolarHBondContact O-CB 3.37Å; L127-L130 PolarHBondContact O-N 2.92Å; L127-L130 VanDerWaalsContact O-N 3.08Å; P128-L130 PolarHBondContact O-N 3.19Å; L130-V138 HydrophobicContact CD2-CG1 4.48Å; L130-V138 WeakPolarHBondContact CD2-O 3.21Å; L130-A141 HydrophobicContact CD2-CB 4.33Å; L130-A142 HydrophobicContact CD2-CB 3.82Å; L130-I145 HydrophobicContact CD1-CD1 3.88Å; L130-I145 HydrophobicContact CD2-CD1 4.04Å; L130-I145 HydrophobicContact CG-CD1 3.93Å; L130-Y163 HydrophobicContact CD1-CE1 4.07Å; L130-Y164 HydrophobicContact CD1-CD2 3.7Å; L130-Y164 HydrophobicContact CD1-CE2 4.03Å; L130-W167 HydrophobicContact CD1-CD2 4.22Å; L130-W167 HydrophobicContact CD1-CG 4.2Å; L130-W167 HydrophobicContact CD2-CZ2 4.23Å
131	N	92.7	Very high	92.9	Very high	115 Å²	115	35.5 Å²	35.5	62%	0.615	19%	0.186	S	C	*	.	G	3₁₀ helix	trans	-97.3	3.2	177.1	-56.8	-59.9	0	0	0	113.3	P128 M129 Y163	P128-N131 PolarHBondContact O-N 3.48Å; P128-N131 VanDerWaalsContact O-N 3.12Å; M129-N131 PolarHBondContact O-N 2.81Å; N131-Y163 PolarHBondContact ND2-OH 3.2Å; N131-Y163 VanDerWaalsContact ND2-OH 3.11Å; N131-Y163 PolarHBondContact OD1-OH 3.38Å
132	R	92.2	Very high	93.2	Very high	59 Å²	59	33.2 Å²	33.2	22%	0.223	17%	0.172	C	C	.	.			trans	-66.8	155.5	175.6	-72.2	-84.7	-165.3	155.9	0.4	110.4	I84 E87 M129 T137 V138	I84-R132 PolarHBondContact O-NH2 3.49Å; E87-R132 IonicContact OE1-CZ 3.93Å; E87-R132 IonicContact OE1-NH1 2.89Å; E87-R132 PolarHBondContact OE1-NH1 2.86Å; M129-R132 WeakPolarHBondContact O-CB 3.49Å; M129-R132 WeakPolarHBondContact O-CG 3.44Å; M129-R132 PolarHBondContact O-N 3.33Å; M129-R132 HydrophobicContact SD-CG 4.33Å; R132-T137 HydrophobicContact CB-CG2 4.03Å; R132-T137 HydrophobicContact CG-CG2 3.93Å; R132-V138 HydrophobicContact CB-CG2 3.98Å; R132-V138 WeakPolarHBondContact O-CG2 3.35Å
133	Q	88.7	Confident	93.3	Very high	192 Å²	192	36 Å²	36	90%	0.897	18%	0.182	S	C	*	.	S	Bend	trans	-80.4	-29.3	179	-65.7	-178	0.6	0	0	112.5	P135	Q133-P135 WeakPolarHBondContact O-CD 3.43Å
134	D	90.6	Very high	93.4	Very high	36 Å²	36	35.7 Å²	35.7	19%	0.193	18%	0.181	C	C	.	.			trans	-73.9	120.6	-178.8	179.5	66.1	0	0	0	111.6	E87 Q91 F136 T137 V138	E87-D134 WeakPolarHBondContact OE2-CB 3.45Å; Q91-D134 PolarHBondContact NE2-OD1 3.12Å; Q91-D134 PolarHBondContact NE2-OD2 3.31Å; D134-F136 VanDerWaalsContact C-N 3.35Å; D134-F136 PolarHBondContact O-N 3.23Å; D134-F136 WeakPolarHBondContact OD2-CB 3.49Å; D134-F136 PolarHBondContact OD2-N 3.36Å; D134-T137 PolarHBondContact O-N 2.8Å; D134-T137 PolarHBondContact OD2-N 3.41Å; D134-T137 PolarHBondContact OD2-OG1 2.94Å; D134-T137 VanDerWaalsContact OD2-OG1 3.07Å; D134-V138 WeakPolarHBondContact O-CG2 3.44Å; D134-V138 PolarHBondContact O-N 2.71Å; D134-V138 VanDerWaalsContact O-N 3.09Å
135	P	89.4	Confident	93.7	Very high	57 Å²	57	33.3 Å²	33.3	37%	0.37	17%	0.166	S	C	.	.	H	α-helix	trans	-59.5	-42.3	-178.7	-26.1	35.5	0	0	0	113	Q133 T137 V138 Y139 Y197	Q133-P135 WeakPolarHBondContact O-CD 3.43Å; P135-T137 PolarHBondContact O-N 2.99Å; P135-V138 PolarHBondContact O-N 3.24Å; P135-Y139 HydrophobicContact CB-CD2 4.2Å; P135-Y139 HydrophobicContact CB-CE2 4.05Å; P135-Y139 WeakPolarHBondContact O-CD2 3.17Å; P135-Y139 PolarHBondContact O-N 3.02Å; P135-Y197 HydrophobicContact CB-CD2 4.48Å; P135-Y197 HydrophobicContact CB-CE2 3.97Å
136	F	91.2	Very high	93.8	Very high	2 Å²	2	31.4 Å²	31.4	1%	0.009	16%	0.158	C	C	.	.	H	α-helix	trans	-63.1	-46.8	-176.9	177.8	-89.9	0	0	0	111.1	I19 K22 A23 V26 Q91 D134 V138 Y139 M140	I19-F136 HydrophobicContact CG2-CE2 4.11Å; K22-F136 HydrophobicContact CB-CD2 3.49Å; K22-F136 VanDerWaalsContact CB-CD2 3.49Å; K22-F136 HydrophobicContact CB-CE2 3.54Å; K22-F136 HydrophobicContact CB-CG 4.48Å; K22-F136 HydrophobicContact CD-CB 4.39Å; K22-F136 HydrophobicContact CD-CD2 3.99Å; K22-F136 HydrophobicContact CG-CD2 4.39Å; A23-F136 HydrophobicContact CB-CE2 4.21Å; A23-F136 HydrophobicContact CB-CZ 4.05Å; V26-F136 HydrophobicContact CG2-CE1 4.04Å; V26-F136 HydrophobicContact CG2-CZ 4.18Å; Q91-F136 HydrophobicContact CB-CD1 3.87Å; Q91-F136 HydrophobicContact CB-CE1 3.94Å; Q91-F136 HydrophobicContact CG-CD1 3.75Å; Q91-F136 HydrophobicContact CG-CE1 4.36Å; D134-F136 VanDerWaalsContact C-N 3.35Å; D134-F136 PolarHBondContact O-N 3.23Å; D134-F136 WeakPolarHBondContact OD2-CB 3.49Å; D134-F136 PolarHBondContact OD2-N 3.36Å; F136-V138 PolarHBondContact O-N 3.42Å; F136-Y139 PolarHBondContact O-N 3.19Å; F136-M140 HydrophobicContact CE1-CB 4.47Å; F136-M140 HydrophobicContact CE1-CE 4Å; F136-M140 HydrophobicContact CE2-CE 3.74Å; F136-M140 HydrophobicContact CZ-CE 3.3Å; F136-M140 WeakPolarHBondContact O-CB 3.41Å; F136-M140 PolarHBondContact O-N 2.87Å
137	T	92.8	Very high	93.9	Very high	0 Å²	0	31.6 Å²	31.6	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-54.2	-50.2	173.5	-63.8	0	0	0	0	110.9	E87 V90 Q91 L94 R132 D134 P135 M140 A141	E87-T137 PolarHBondContact OE2-OG1 3Å; V90-T137 HydrophobicContact CG1-CG2 3.91Å; Q91-T137 WeakPolarHBondContact CG-OG1 3.24Å; L94-T137 HydrophobicContact CD1-CG2 3.52Å; R132-T137 HydrophobicContact CB-CG2 4.03Å; R132-T137 HydrophobicContact CG-CG2 3.93Å; D134-T137 PolarHBondContact O-N 2.8Å; D134-T137 PolarHBondContact OD2-N 3.41Å; D134-T137 PolarHBondContact OD2-OG1 2.94Å; D134-T137 VanDerWaalsContact OD2-OG1 3.07Å; P135-T137 PolarHBondContact O-N 2.99Å; T137-M140 PolarHBondContact O-N 2.86Å; T137-A141 VanDerWaalsContact O-CB 3.29Å; T137-A141 WeakPolarHBondContact O-CB 3.4Å; T137-A141 PolarHBondContact O-N 2.87Å
138	V	94.1	Very high	93.9	Very high	13 Å²	13	31 Å²	31	8%	0.079	16%	0.156	C	C	.	.	H	α-helix	trans	-60.2	-50.7	-178.6	168.6	0	0	0	0	111.7	L130 R132 D134 P135 F136 A141 A142 W167	L130-V138 HydrophobicContact CD2-CG1 4.48Å; L130-V138 WeakPolarHBondContact CD2-O 3.21Å; R132-V138 HydrophobicContact CB-CG2 3.98Å; R132-V138 WeakPolarHBondContact O-CG2 3.35Å; D134-V138 WeakPolarHBondContact O-CG2 3.44Å; D134-V138 PolarHBondContact O-N 2.71Å; D134-V138 VanDerWaalsContact O-N 3.09Å; P135-V138 PolarHBondContact O-N 3.24Å; F136-V138 PolarHBondContact O-N 3.42Å; V138-A141 PolarHBondContact O-N 2.84Å; V138-A142 PolarHBondContact O-N 3.11Å; V138-W167 HydrophobicContact CG1-CZ2 3.58Å
139	Y	93.3	Very high	93.9	Very high	21 Å²	21	27.7 Å²	27.7	8%	0.082	14%	0.135	C	C	.	.	H	α-helix	trans	-74.7	-29.3	-176.8	-65.5	-68.5	0	0	0	112.9	P135 F136 R143 W167 Q171 Y197 V201	P135-Y139 HydrophobicContact CB-CD2 4.2Å; P135-Y139 HydrophobicContact CB-CE2 4.05Å; P135-Y139 WeakPolarHBondContact O-CD2 3.17Å; P135-Y139 PolarHBondContact O-N 3.02Å; F136-Y139 PolarHBondContact O-N 3.19Å; Y139-R143 WeakPolarHBondContact O-CG 3.22Å; Y139-R143 PolarHBondContact O-N 3.45Å; Y139-R143 VanDerWaalsContact O-N 3.11Å; Y139-W167 AromaticContact CD1-CH2 3.86Å; Y139-W167 HydrophobicContact CD1-CH2 3.86Å; Y139-W167 HydrophobicContact CD1-CZ2 4.26Å; Y139-W167 AromaticContact CE1-CH2 3.98Å; Y139-W167 HydrophobicContact CE1-CH2 3.98Å; Y139-W167 HydrophobicContact CE1-CZ2 4.12Å; Y139-Q171 PolarHBondContact OH-OE1 2.95Å; Y139-Y197 HydrophobicContact CD1-CG 4.49Å; Y139-Y197 AromaticContact CD2-CD1 3.14Å; Y139-Y197 HydrophobicContact CD2-CD1 3.14Å; Y139-Y197 AromaticContact CD2-CD2 3.84Å; Y139-Y197 HydrophobicContact CD2-CD2 3.84Å; Y139-Y197 AromaticContact CD2-CE1 3.83Å; Y139-Y197 HydrophobicContact CD2-CE1 3.83Å; Y139-Y197 HydrophobicContact CD2-CE2 4.45Å; Y139-Y197 AromaticContact CD2-CG 3.16Å; Y139-Y197 HydrophobicContact CD2-CG 3.16Å; Y139-Y197 AromaticContact CE2-CD1 3.78Å; Y139-Y197 HydrophobicContact CE2-CD1 3.78Å; Y139-Y197 AromaticContact CE2-CD2 3.59Å; Y139-Y197 HydrophobicContact CE2-CD2 3.59Å; Y139-Y197 HydrophobicContact CE2-CE2 4.39Å; Y139-Y197 AromaticContact CE2-CG 3.25Å; Y139-Y197 HydrophobicContact CE2-CG 3.25Å; Y139-Y197 AromaticContact CG-CD1 3.66Å; Y139-Y197 HydrophobicContact CG-CD1 3.66Å; Y139-Y197 AromaticContact CG-CG 3.86Å; Y139-Y197 HydrophobicContact CG-CG 3.86Å; Y139-Y197 AromaticContact CZ-CG 4Å; Y139-V201 HydrophobicContact CD1-CG2 3.72Å; Y139-V201 HydrophobicContact CE1-CG2 3.47Å; Y139-V201 VanDerWaalsContact CE1-CG2 3.47Å
140	M	93.9	Very high	93.9	Very high	3 Å²	3	28.1 Å²	28.1	2%	0.015	14%	0.14	C	C	.	.	H	α-helix	trans	-68.2	-43.6	171.8	-169.2	63.1	77.5	0	0	110.9	I19 A23 L94 D98 F136 T137 A142 R143 I144	I19-M140 HydrophobicContact CG2-CE 3.69Å; A23-M140 HydrophobicContact CB-CE 4.16Å; L94-M140 HydrophobicContact CB-CB 4.29Å; L94-M140 HydrophobicContact CB-CG 3.77Å; D98-M140 HydrophobicContact CB-CG 4.42Å; D98-M140 HydrophobicContact CB-SD 3.57Å; D98-M140 VanDerWaalsContact CB-SD 3.57Å; D98-M140 VanDerWaalsContact CG-SD 3.58Å; F136-M140 HydrophobicContact CE1-CB 4.47Å; F136-M140 HydrophobicContact CE1-CE 4Å; F136-M140 HydrophobicContact CE2-CE 3.74Å; F136-M140 HydrophobicContact CZ-CE 3.3Å; F136-M140 WeakPolarHBondContact O-CB 3.41Å; F136-M140 PolarHBondContact O-N 2.87Å; T137-M140 PolarHBondContact O-N 2.86Å; M140-A142 VanDerWaalsContact C-N 3.34Å; M140-A142 PolarHBondContact O-N 3.34Å; M140-R143 WeakPolarHBondContact O-CB 3.1Å; M140-R143 PolarHBondContact O-N 3.01Å; M140-I144 HydrophobicContact CG-CD1 4.27Å; M140-I144 WeakPolarHBondContact O-CG1 3.23Å; M140-I144 PolarHBondContact O-N 3.42Å
141	A	95.8	Very high	93.9	Very high	0 Å²	0	30.3 Å²	30.3	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-60.1	-43.8	174.2	0	0	0	0	0	111.6	L94 M129 L130 T137 V138 R143 I144 I145	L94-A141 HydrophobicContact CD1-CB 4.45Å; L94-A141 HydrophobicContact CD2-CB 4.47Å; M129-A141 HydrophobicContact CB-CB 3.51Å; M129-A141 HydrophobicContact CG-CB 4.44Å; L130-A141 HydrophobicContact CD2-CB 4.33Å; T137-A141 VanDerWaalsContact O-CB 3.29Å; T137-A141 WeakPolarHBondContact O-CB 3.4Å; T137-A141 PolarHBondContact O-N 2.87Å; V138-A141 PolarHBondContact O-N 2.84Å; A141-R143 VanDerWaalsContact C-N 3.32Å; A141-R143 PolarHBondContact O-N 3.26Å; A141-I144 PolarHBondContact O-N 3.33Å; A141-I145 WeakPolarHBondContact O-CD1 3.34Å; A141-I145 VanDerWaalsContact O-CG1 3.23Å; A141-I145 WeakPolarHBondContact O-CG1 3.23Å; A141-I145 PolarHBondContact O-N 3.35Å
142	A	95.9	Very high	93.8	Very high	0 Å²	0	25.8 Å²	25.8	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-56.6	-43.9	174.2	0	0	0	0	0	112.3	L130 V138 M140 I144 I145 A146 Y164 W167	L130-A142 HydrophobicContact CD2-CB 3.82Å; V138-A142 PolarHBondContact O-N 3.11Å; M140-A142 VanDerWaalsContact C-N 3.34Å; M140-A142 PolarHBondContact O-N 3.34Å; A142-I144 PolarHBondContact O-N 2.92Å; A142-I145 PolarHBondContact O-N 3.13Å; A142-A146 PolarHBondContact O-N 3.45Å; A142-Y164 HydrophobicContact CB-CE2 4.21Å; A142-Y164 PolarHBondContact O-OH 2.91Å; A142-W167 HydrophobicContact CB-CH2 3.48Å; A142-W167 VanDerWaalsContact CB-CH2 3.48Å; A142-W167 HydrophobicContact CB-CZ2 4.36Å; A142-W167 HydrophobicContact CB-CZ3 3.56Å
143	R	95	Very high	93.4	Very high	58 Å²	58	32.4 Å²	32.4	22%	0.219	16%	0.159	C	C	.	.	H	α-helix	trans	-60.5	-46.5	175.7	-71.6	171.3	59.2	75.5	1.5	112.2	D98 Y139 M140 A141 I145 A146 K147 C200	D98-R143 IonicContact OD2-NE 2.69Å; D98-R143 IonicContact OD2-NH2 3.91Å; Y139-R143 WeakPolarHBondContact O-CG 3.22Å; Y139-R143 PolarHBondContact O-N 3.45Å; Y139-R143 VanDerWaalsContact O-N 3.11Å; M140-R143 WeakPolarHBondContact O-CB 3.1Å; M140-R143 PolarHBondContact O-N 3.01Å; A141-R143 VanDerWaalsContact C-N 3.32Å; A141-R143 PolarHBondContact O-N 3.26Å; R143-I145 VanDerWaalsContact C-N 3.32Å; R143-I145 PolarHBondContact O-N 3.24Å; R143-A146 PolarHBondContact O-N 3.09Å; R143-K147 VanDerWaalsContact O-CG 3.31Å; R143-K147 WeakPolarHBondContact O-CG 3.04Å; R143-K147 PolarHBondContact O-N 3.47Å; R143-C200 WeakPolarHBondContact CD-SG 3.12Å; R143-C200 WeakPolarHBondContact CG-SG 3.44Å
144	I	96.4	Very high	93.5	Very high	0 Å²	0	25.4 Å²	25.4	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-60.7	-44.4	177.8	-67.2	162.5	0	0	0	110.1	L94 V97 D98 L101 F126 M140 A141 A142 A146 K147 L148	L94-I144 HydrophobicContact CB-CD1 4.22Å; L94-I144 HydrophobicContact CD2-CD1 3.78Å; L94-I144 WeakPolarHBondContact O-CD1 3.28Å; V97-I144 HydrophobicContact CB-CD1 4.06Å; V97-I144 HydrophobicContact CG1-CD1 3.9Å; V97-I144 HydrophobicContact CG1-CG1 4.27Å; V97-I144 HydrophobicContact CG1-CG2 4.03Å; D98-I144 HydrophobicContact CB-CD1 4.38Å; D98-I144 HydrophobicContact CB-CG1 4.12Å; L101-I144 HydrophobicContact CD1-CG2 4.02Å; F126-I144 HydrophobicContact CD1-CG2 3.77Å; F126-I144 HydrophobicContact CE1-CG2 3.63Å; F126-I144 HydrophobicContact CG-CG2 4.45Å; F126-I144 HydrophobicContact CZ-CG2 4.22Å; M140-I144 HydrophobicContact CG-CD1 4.27Å; M140-I144 WeakPolarHBondContact O-CG1 3.23Å; M140-I144 PolarHBondContact O-N 3.42Å; A141-I144 PolarHBondContact O-N 3.33Å; A142-I144 PolarHBondContact O-N 2.92Å; I144-A146 PolarHBondContact O-N 2.89Å; I144-K147 WeakPolarHBondContact O-CB 3.16Å; I144-K147 PolarHBondContact O-N 3.38Å; I144-L148 HydrophobicContact CG2-CD1 3.98Å; I144-L148 HydrophobicContact CG2-CG 4.26Å; I144-L148 VanDerWaalsContact O-CG 3.3Å; I144-L148 WeakPolarHBondContact O-CG 3.45Å; I144-L148 PolarHBondContact O-N 3.28Å
145	I	97.3	Very high	93.7	Very high	1 Å²	1	26.7 Å²	26.7	1%	0.005	13%	0.132	C	C	.	.	H	α-helix	trans	-58.7	-47	176.5	-67.8	160.9	0	0	0	110.9	F126 L127 L130 A141 A142 R143 K147 L148 A149 M156 Y164	F126-I145 HydrophobicContact CB-CD1 4.05Å; F126-I145 HydrophobicContact CB-CG1 3.59Å; L127-I145 HydrophobicContact CD2-CD1 3.99Å; L127-I145 HydrophobicContact CD2-CG2 4.41Å; L130-I145 HydrophobicContact CD1-CD1 3.88Å; L130-I145 HydrophobicContact CD2-CD1 4.04Å; L130-I145 HydrophobicContact CG-CD1 3.93Å; A141-I145 WeakPolarHBondContact O-CD1 3.34Å; A141-I145 VanDerWaalsContact O-CG1 3.23Å; A141-I145 WeakPolarHBondContact O-CG1 3.23Å; A141-I145 PolarHBondContact O-N 3.35Å; A142-I145 PolarHBondContact O-N 3.13Å; R143-I145 VanDerWaalsContact C-N 3.32Å; R143-I145 PolarHBondContact O-N 3.24Å; I145-K147 VanDerWaalsContact C-N 3.33Å; I145-K147 PolarHBondContact O-N 2.77Å; I145-L148 PolarHBondContact O-N 2.91Å; I145-A149 WeakPolarHBondContact O-CB 3.2Å; I145-A149 PolarHBondContact O-N 3.48Å; I145-M156 HydrophobicContact CG2-CE 3.58Å; I145-Y164 HydrophobicContact CB-CE2 4.32Å; I145-Y164 HydrophobicContact CD1-CE2 4.49Å; I145-Y164 HydrophobicContact CG2-CD1 4.02Å; I145-Y164 HydrophobicContact CG2-CD2 4.1Å; I145-Y164 HydrophobicContact CG2-CE1 3.9Å; I145-Y164 HydrophobicContact CG2-CE2 4.01Å; I145-Y164 HydrophobicContact CG2-CG 4.13Å
146	A	96.4	Very high	93.9	Very high	0 Å²	0	24 Å²	24	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-62.9	-38.4	177	0	0	0	0	0	112.5	A142 R143 I144 A149 A150 C204 L207 M208	A142-A146 PolarHBondContact O-N 3.45Å; R143-A146 PolarHBondContact O-N 3.09Å; I144-A146 PolarHBondContact O-N 2.89Å; A146-A149 PolarHBondContact O-N 3.46Å; A146-A150 VanDerWaalsContact O-CB 3.27Å; A146-A150 WeakPolarHBondContact O-CB 3.42Å; A146-A150 PolarHBondContact O-N 2.8Å; A146-C204 HydrophobicContact CB-CB 3.94Å; A146-L207 HydrophobicContact CB-CB 4.38Å; A146-L207 HydrophobicContact CB-CD2 3.98Å; A146-L207 HydrophobicContact CB-CG 4.41Å; A146-M208 HydrophobicContact CB-CG 4.38Å; A146-M208 HydrophobicContact CB-SD 4.41Å
147	K	95.9	Very high	94	Very high	4 Å²	4	30.3 Å²	30.3	2%	0.017	15%	0.145	C	C	.	.	H	α-helix	trans	-63.9	-47.1	174.6	-73.7	175.8	168.2	-175.8	0	111.8	D98 L101 R143 I144 I145 A149 A150 W151 L207	D98-K147 PolarHBondContact O-NZ 3.47Å; D98-K147 VanDerWaalsContact O-NZ 3.16Å; D98-K147 WeakPolarHBondContact OD1-CD 3.36Å; D98-K147 VanDerWaalsContact OD1-CE 3.28Å; D98-K147 WeakPolarHBondContact OD1-CE 3.37Å; D98-K147 IonicContact OD1-NZ 2.77Å; D98-K147 PolarHBondContact OD1-NZ 3.48Å; D98-K147 IonicContact OD2-NZ 3.3Å; D98-K147 PolarHBondContact OD2-NZ 3.35Å; D98-K147 VanDerWaalsContact OD2-NZ 3.08Å; L101-K147 HydrophobicContact CB-CD 4.34Å; L101-K147 HydrophobicContact CD1-CB 4.49Å; R143-K147 VanDerWaalsContact O-CG 3.31Å; R143-K147 WeakPolarHBondContact O-CG 3.04Å; R143-K147 PolarHBondContact O-N 3.47Å; I144-K147 WeakPolarHBondContact O-CB 3.16Å; I144-K147 PolarHBondContact O-N 3.38Å; I145-K147 VanDerWaalsContact C-N 3.33Å; I145-K147 PolarHBondContact O-N 2.77Å; K147-A149 VanDerWaalsContact C-N 3.31Å; K147-A149 PolarHBondContact O-N 2.84Å; K147-A150 PolarHBondContact O-N 3.06Å; K147-W151 HydrophobicContact CB-CD2 4.24Å; K147-W151 HydrophobicContact CB-CE3 3.68Å; K147-W151 HydrophobicContact CB-CH2 4.21Å; K147-W151 HydrophobicContact CB-CZ3 3.67Å; K147-W151 HydrophobicContact CD-CE3 4.38Å; K147-W151 HydrophobicContact CD-CH2 3.64Å; K147-W151 HydrophobicContact CD-CZ3 3.51Å; K147-W151 HydrophobicContact CG-CD2 4.47Å; K147-W151 HydrophobicContact CG-CE3 3.96Å; K147-W151 HydrophobicContact CG-CH2 3.52Å; K147-W151 HydrophobicContact CG-CZ2 4.02Å; K147-W151 HydrophobicContact CG-CZ3 3.47Å; K147-W151 VanDerWaalsContact CG-CZ3 3.47Å; K147-W151 VanDerWaalsContact O-CB 3.3Å; K147-W151 WeakPolarHBondContact O-CB 3.43Å; K147-W151 PolarHBondContact O-N 3.38Å; K147-L207 HydrophobicContact CB-CD2 4.39Å; K147-L207 HydrophobicContact CG-CD2 3.78Å
148	L	95.9	Very high	94.1	Very high	0 Å²	0	32.6 Å²	32.6	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-59.4	-43.4	175.9	-70.2	172.7	0	0	0	111.1	L101 V108 F111 F112 W123 F126 I144 I145 G152	L101-L148 HydrophobicContact CD1-CD2 4.32Å; V108-L148 HydrophobicContact CB-CD2 3.9Å; V108-L148 HydrophobicContact CG1-CD2 4.01Å; F111-L148 HydrophobicContact CB-CD2 4.3Å; F111-L148 HydrophobicContact CD2-CD2 4.02Å; F111-L148 HydrophobicContact CG-CD2 4.48Å; F112-L148 HydrophobicContact CE2-CB 4.43Å; F112-L148 HydrophobicContact CE2-CD2 4.23Å; F112-L148 HydrophobicContact CZ-CB 4.27Å; F112-L148 WeakPolarHBondContact CZ-O 3.18Å; W123-L148 HydrophobicContact CH2-CB 4.34Å; W123-L148 HydrophobicContact CZ3-CB 3.66Å; F126-L148 HydrophobicContact CD2-CD1 3.52Å; F126-L148 HydrophobicContact CE2-CD1 3.46Å; F126-L148 VanDerWaalsContact CE2-CD1 3.46Å; F126-L148 HydrophobicContact CG-CD1 4.15Å; F126-L148 HydrophobicContact CZ-CD1 4.03Å; I144-L148 HydrophobicContact CG2-CD1 3.98Å; I144-L148 HydrophobicContact CG2-CG 4.26Å; I144-L148 VanDerWaalsContact O-CG 3.3Å; I144-L148 WeakPolarHBondContact O-CG 3.45Å; I144-L148 PolarHBondContact O-N 3.28Å; I145-L148 PolarHBondContact O-N 2.91Å; L148-G152 WeakPolarHBondContact O-CA 3.33Å; L148-G152 PolarHBondContact O-N 3.35Å
149	A	95.3	Very high	94.1	Very high	1 Å²	1	36.3 Å²	36.3	1%	0.008	20%	0.195	C	C	.	.	H	α-helix	trans	-68.8	-39.5	179.1	0	0	0	0	0	113.7	W123 I145 A146 K147 M208 Y214	W123-A149 HydrophobicContact CH2-CB 4.08Å; W123-A149 HydrophobicContact CZ3-CB 4.19Å; I145-A149 WeakPolarHBondContact O-CB 3.2Å; I145-A149 PolarHBondContact O-N 3.48Å; A146-A149 PolarHBondContact O-N 3.46Å; K147-A149 VanDerWaalsContact C-N 3.31Å; K147-A149 PolarHBondContact O-N 2.84Å; A149-M208 HydrophobicContact CB-CE 3.87Å; A149-M208 HydrophobicContact CB-SD 3.36Å; A149-M208 WeakPolarHBondContact CB-SD 3.29Å; A149-Y214 HydrophobicContact CB-CE2 3.9Å; A149-Y214 WeakPolarHBondContact O-CE2 3.44Å; A149-Y214 PolarHBondContact O-OH 3.28Å
150	A	94.4	Very high	94.2	Very high	21 Å²	21	37.3 Å²	37.3	17%	0.174	20%	0.201	C	C	.	.	H	α-helix	trans	-86.4	-28.8	-175.7	0	0	0	0	0	114.5	A146 K147 L207 V211	A146-A150 VanDerWaalsContact O-CB 3.27Å; A146-A150 WeakPolarHBondContact O-CB 3.42Å; A146-A150 PolarHBondContact O-N 2.8Å; K147-A150 PolarHBondContact O-N 3.06Å; A150-L207 HydrophobicContact CB-CD1 3.56Å; A150-L207 HydrophobicContact CB-CD2 4.4Å; A150-L207 HydrophobicContact CB-CG 3.53Å; A150-L207 WeakPolarHBondContact CB-O 3.34Å; A150-V211 HydrophobicContact CB-CG2 4.42Å
151	W	94.8	Very high	94.3	Very high	54 Å²	54	37.8 Å²	37.8	21%	0.205	20%	0.204	C	C	.	.	H	α-helix	trans	-103.9	-15.2	-179.3	-53.6	-26	0	0	0	112.7	L101 H105 V108 K147	L101-W151 HydrophobicContact CB-CZ3 4.16Å; L101-W151 WeakPolarHBondContact O-CZ3 3.31Å; H105-W151 HydrophobicContact CB-CB 4.3Å; H105-W151 HydrophobicContact CB-CD2 3.85Å; H105-W151 HydrophobicContact CB-CE3 3.92Å; H105-W151 HydrophobicContact CB-CG 4.03Å; H105-W151 HydrophobicContact CB-CZ3 4.48Å; H105-W151 AromaticContact CD2-CD2 3.9Å; H105-W151 AromaticContact CD2-CE2 3.78Å; H105-W151 AromaticContact CD2-CE3 3.74Å; H105-W151 AromaticContact CD2-CH2 3.32Å; H105-W151 WeakPolarHBondContact CD2-CH2 3.44Å; H105-W151 AromaticContact CD2-CZ2 3.53Å; H105-W151 AromaticContact CD2-CZ3 3.44Å; H105-W151 VanDerWaalsContact CD2-CZ3 3.44Å; H105-W151 WeakPolarHBondContact CD2-CZ3 3.5Å; H105-W151 AromaticContact CE1-CZ2 3.84Å; H105-W151 AromaticContact CG-CD2 3.75Å; H105-W151 AromaticContact CG-CE2 3.81Å; H105-W151 AromaticContact CG-CE3 3.91Å; H105-W151 AromaticContact ND1-CE2 3.95Å; H105-W151 AromaticContact NE2-CE2 3.92Å; H105-W151 AromaticContact NE2-CH2 3.47Å; H105-W151 WeakPolarHBondContact NE2-CH2 3.21Å; H105-W151 AromaticContact NE2-CZ2 3.4Å; H105-W151 WeakPolarHBondContact NE2-CZ2 3.43Å; V108-W151 HydrophobicContact CG1-CB 4.02Å; V108-W151 HydrophobicContact CG1-CE3 3.96Å; V108-W151 HydrophobicContact CG2-CB 4.05Å; V108-W151 WeakPolarHBondContact CG2-O 3.39Å; K147-W151 HydrophobicContact CB-CD2 4.24Å; K147-W151 HydrophobicContact CB-CE3 3.68Å; K147-W151 HydrophobicContact CB-CH2 4.21Å; K147-W151 HydrophobicContact CB-CZ3 3.67Å; K147-W151 HydrophobicContact CD-CE3 4.38Å; K147-W151 HydrophobicContact CD-CH2 3.64Å; K147-W151 HydrophobicContact CD-CZ3 3.51Å; K147-W151 HydrophobicContact CG-CD2 4.47Å; K147-W151 HydrophobicContact CG-CE3 3.96Å; K147-W151 HydrophobicContact CG-CH2 3.52Å; K147-W151 HydrophobicContact CG-CZ2 4.02Å; K147-W151 HydrophobicContact CG-CZ3 3.47Å; K147-W151 VanDerWaalsContact CG-CZ3 3.47Å; K147-W151 VanDerWaalsContact O-CB 3.3Å; K147-W151 WeakPolarHBondContact O-CB 3.43Å; K147-W151 PolarHBondContact O-N 3.38Å
152	G	90.4	Very high	94.4	Very high	19 Å²	19	41.9 Å²	41.9	20%	0.196	23%	0.226	C	C	.	.	S	Bend	trans	-69.9	162.6	177	0	0	0	0	0	113.3	L148	L148-G152 WeakPolarHBondContact O-CA 3.33Å; L148-G152 PolarHBondContact O-N 3.35Å
153	K	84.9	Confident	94.4	Very high	198 Å²	198	45.8 Å²	45.8	86%	0.861	24%	0.241	S	C	*	.	S	Bend	trans	-90	-22.6	173.7	-65.3	-177.5	-179.3	176.4	0	112.8
154	E	90.4	Very high	94.6	Very high	46 Å²	46	43 Å²	43	22%	0.215	23%	0.231	C	C	.	.	S	Bend	trans	-96.1	129.5	179.7	-63.2	-178.8	-175.5	0	0	108.9	F112 R116	F112-E154 HydrophobicContact CD1-CB 3.89Å; F112-E154 HydrophobicContact CD1-CG 4.08Å; F112-E154 WeakPolarHBondContact CD1-OE2 3.39Å; F112-E154 HydrophobicContact CE1-CB 3.82Å; R116-E154 IonicContact CZ-OE1 3.69Å; R116-E154 IonicContact NE-OE1 3.57Å; R116-E154 PolarHBondContact NE-OE1 3.37Å; R116-E154 IonicContact NH2-OE1 3.01Å; R116-E154 PolarHBondContact NH2-OE1 2.84Å
155	L	93.6	Very high	94.6	Very high	62 Å²	62	43.1 Å²	43.1	33%	0.325	23%	0.231	S	C	.	.	P	Polyproline II helix	trans	-78.5	142.2	176.6	-64.3	175.9	0	0	0	110.2	E157 V211 E213 Y214	L155-E157 HydrophobicContact CB-CG 4.18Å; L155-V211 HydrophobicContact CD2-CG1 3.84Å; L155-E213 HydrophobicContact CD1-CB 4.07Å; L155-E213 HydrophobicContact CD1-CG 3.72Å; L155-Y214 WeakPolarHBondContact CA-OH 3.35Å; L155-Y214 HydrophobicContact CD2-CE1 4.32Å; L155-Y214 HydrophobicContact CD2-CE2 4.49Å
156	M	95.1	Very high	94.6	Very high	1 Å²	1	46.8 Å²	46.8	1%	0.005	25%	0.251	C	S	.	.	P	Polyproline II helix	trans	-78.7	123.9	167.2	-173.4	-171.9	-72.1	0	0	108.4	W123 I145 D160 L161 Y214	W123-M156 HydrophobicContact CB-CE 4.4Å; W123-M156 HydrophobicContact CD2-CB 4.23Å; W123-M156 HydrophobicContact CD2-CE 3.57Å; W123-M156 HydrophobicContact CD2-CG 4.14Å; W123-M156 HydrophobicContact CE3-CE 3.29Å; W123-M156 HydrophobicContact CG-CE 4.06Å; W123-M156 HydrophobicContact CG-CG 4.27Å; W123-M156 HydrophobicContact CH2-CB 4.19Å; W123-M156 HydrophobicContact CH2-CE 4.36Å; W123-M156 HydrophobicContact CZ2-CB 3.71Å; W123-M156 HydrophobicContact CZ2-CG 4.49Å; W123-M156 HydrophobicContact CZ3-CE 3.71Å; I145-M156 HydrophobicContact CG2-CE 3.58Å; M156-D160 HydrophobicContact CG-CB 3.84Å; M156-D160 HydrophobicContact SD-CB 4.29Å; M156-L161 HydrophobicContact CB-CD1 4.42Å; M156-L161 HydrophobicContact CG-CB 4.01Å; M156-L161 HydrophobicContact CG-CD1 4.4Å; M156-L161 VanDerWaalsContact SD-CA 3.59Å; M156-L161 HydrophobicContact SD-CB 4.29Å; M156-L161 HydrophobicContact SD-CD1 4.17Å; M156-Y214 HydrophobicContact CB-CE1 4.3Å; M156-Y214 PolarHBondContact N-OH 3.22Å; M156-Y214 WeakPolarHBondContact O-CE1 3.32Å
157	E	93.3	Very high	94.5	Very high	135 Å²	135	47.9 Å²	47.9	63%	0.631	26%	0.255	S	S	*	.			trans	-132.9	167.6	-173.9	-64.8	-178.9	-179.8	0	0	111.3	L155 S159	L155-E157 HydrophobicContact CB-CG 4.18Å; E157-S159 PolarHBondContact O-N 3.03Å
158	G	93.3	Very high	94.6	Very high	48 Å²	48	47.7 Å²	47.7	50%	0.495	25%	0.254	S	S	.	.	H	α-helix	trans	60.8	-132	171	0	0	0	0	0	114.3	D160 L161 N162	G158-D160 VanDerWaalsContact C-N 3.33Å; G158-D160 PolarHBondContact O-N 3.36Å; G158-L161 PolarHBondContact O-N 3.1Å; G158-N162 WeakPolarHBondContact O-CB 3.3Å; G158-N162 VanDerWaalsContact O-CG 3.32Å; G158-N162 PolarHBondContact O-N 3.49Å; G158-N162 VanDerWaalsContact O-N 3.11Å; G158-N162 PolarHBondContact O-ND2 3.39Å
159	S	94.4	Very high	94.5	Very high	91 Å²	91	49.7 Å²	49.7	64%	0.636	26%	0.263	S	S	*	.	H	α-helix	trans	-63.5	-35.9	-174.5	51.7	0	0	0	0	113.4	E157 N162 Y163	E157-S159 PolarHBondContact O-N 3.03Å; S159-N162 PolarHBondContact O-N 3.36Å; S159-Y163 VanDerWaalsContact O-CB 3.28Å; S159-Y163 WeakPolarHBondContact O-CB 3.46Å; S159-Y163 PolarHBondContact O-N 3.3Å
160	D	95.8	Very high	94.4	Very high	41 Å²	41	53.9 Å²	53.9	22%	0.219	29%	0.289	C	S	.	.	H	α-helix	trans	-67.3	-45.7	-177.5	-68.1	-18.1	0	0	0	110.6	W123 L127 M156 G158 Y163 Y164	W123-D160 HydrophobicContact CB-CB 4.41Å; L127-D160 HydrophobicContact CD1-CB 3.85Å; M156-D160 HydrophobicContact CG-CB 3.84Å; M156-D160 HydrophobicContact SD-CB 4.29Å; G158-D160 VanDerWaalsContact C-N 3.33Å; G158-D160 PolarHBondContact O-N 3.36Å; D160-Y163 PolarHBondContact O-N 2.67Å; D160-Y164 PolarHBondContact O-N 3.1Å
161	L	96.9	Very high	94.2	Very high	14 Å²	14	54.9 Å²	54.9	7%	0.073	29%	0.29	C	S	.	.	H	α-helix	trans	-63.4	-46.9	176.6	-175.4	64.3	0	0	0	111.2	M156 G158 Y163 Y164 F165 M208 Y214 A217	M156-L161 HydrophobicContact CB-CD1 4.42Å; M156-L161 HydrophobicContact CG-CB 4.01Å; M156-L161 HydrophobicContact CG-CD1 4.4Å; M156-L161 VanDerWaalsContact SD-CA 3.59Å; M156-L161 HydrophobicContact SD-CB 4.29Å; M156-L161 HydrophobicContact SD-CD1 4.17Å; G158-L161 PolarHBondContact O-N 3.1Å; L161-Y163 VanDerWaalsContact C-N 3.32Å; L161-Y163 PolarHBondContact O-N 2.89Å; L161-Y164 PolarHBondContact O-N 2.81Å; L161-F165 HydrophobicContact CD1-CD1 4.06Å; L161-F165 HydrophobicContact CD1-CD2 4.25Å; L161-F165 HydrophobicContact CD1-CE1 3.71Å; L161-F165 HydrophobicContact CD1-CE2 3.89Å; L161-F165 HydrophobicContact CD1-CG 4.35Å; L161-F165 HydrophobicContact CD1-CZ 3.62Å; L161-F165 HydrophobicContact CD2-CE2 4.22Å; L161-F165 HydrophobicContact CG-CD2 4.14Å; L161-F165 HydrophobicContact CG-CE2 4.01Å; L161-F165 HydrophobicContact CG-CG 4.49Å; L161-F165 HydrophobicContact CG-CZ 4.27Å; L161-F165 WeakPolarHBondContact O-CB 3.27Å; L161-F165 PolarHBondContact O-N 3.26Å; L161-M208 HydrophobicContact CD1-CE 3.87Å; L161-Y214 HydrophobicContact CD1-CD1 3.89Å; L161-Y214 HydrophobicContact CD1-CE1 4.02Å; L161-Y214 HydrophobicContact CD2-CD1 4.24Å; L161-A217 HydrophobicContact CD2-CB 3.72Å
162	N	96.4	Very high	94	Very high	86 Å²	86	52.3 Å²	52.3	46%	0.46	28%	0.28	S	S	.	.	H	α-helix	trans	-61	-42.4	178.8	-75	-25.6	0	0	0	111.8	G158 S159 N166	G158-N162 WeakPolarHBondContact O-CB 3.3Å; G158-N162 VanDerWaalsContact O-CG 3.32Å; G158-N162 PolarHBondContact O-N 3.49Å; G158-N162 VanDerWaalsContact O-N 3.11Å; G158-N162 PolarHBondContact O-ND2 3.39Å; S159-N162 PolarHBondContact O-N 3.36Å; N162-N166 VanDerWaalsContact O-CB 3.24Å; N162-N166 WeakPolarHBondContact O-CB 3.16Å; N162-N166 PolarHBondContact O-N 3.44Å; N162-N166 PolarHBondContact O-ND2 2.93Å; N162-N166 VanDerWaalsContact O-ND2 3.1Å
163	Y	97.1	Very high	93.7	Very high	82 Å²	82	53.9 Å²	53.9	32%	0.322	29%	0.288	S	S	.	.	H	α-helix	trans	-61.1	-48.7	175.9	175.6	-100.2	0	0	0	111.1	L127 L130 N131 S159 D160 L161 N166 W167	L127-Y163 HydrophobicContact CB-CE1 4.41Å; L127-Y163 HydrophobicContact CD2-CD1 4.03Å; L127-Y163 HydrophobicContact CD2-CE1 4.33Å; L130-Y163 HydrophobicContact CD1-CE1 4.07Å; N131-Y163 PolarHBondContact ND2-OH 3.2Å; N131-Y163 VanDerWaalsContact ND2-OH 3.11Å; N131-Y163 PolarHBondContact OD1-OH 3.38Å; S159-Y163 VanDerWaalsContact O-CB 3.28Å; S159-Y163 WeakPolarHBondContact O-CB 3.46Å; S159-Y163 PolarHBondContact O-N 3.3Å; D160-Y163 PolarHBondContact O-N 2.67Å; L161-Y163 VanDerWaalsContact C-N 3.32Å; L161-Y163 PolarHBondContact O-N 2.89Å; Y163-N166 PolarHBondContact O-N 2.93Å; Y163-W167 WeakPolarHBondContact O-CB 3.47Å; Y163-W167 PolarHBondContact O-N 3.39Å
164	Y	97.6	Very high	93.2	Very high	0 Å²	0	47 Å²	47	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-66.8	-41.7	-178.3	-171.4	-126.5	0	0	0	112.9	L130 A142 I145 D160 L161 W167 I168 C204 M208	L130-Y164 HydrophobicContact CD1-CD2 3.7Å; L130-Y164 HydrophobicContact CD1-CE2 4.03Å; A142-Y164 HydrophobicContact CB-CE2 4.21Å; A142-Y164 PolarHBondContact O-OH 2.91Å; I145-Y164 HydrophobicContact CB-CE2 4.32Å; I145-Y164 HydrophobicContact CD1-CE2 4.49Å; I145-Y164 HydrophobicContact CG2-CD1 4.02Å; I145-Y164 HydrophobicContact CG2-CD2 4.1Å; I145-Y164 HydrophobicContact CG2-CE1 3.9Å; I145-Y164 HydrophobicContact CG2-CE2 4.01Å; I145-Y164 HydrophobicContact CG2-CG 4.13Å; D160-Y164 PolarHBondContact O-N 3.1Å; L161-Y164 PolarHBondContact O-N 2.81Å; Y164-W167 HydrophobicContact CD2-CE3 4.34Å; Y164-W167 AromaticContact CE2-CE3 3.96Å; Y164-W167 HydrophobicContact CE2-CE3 3.96Å; Y164-W167 HydrophobicContact CE2-CZ3 4.25Å; Y164-W167 WeakPolarHBondContact O-CB 3.37Å; Y164-W167 PolarHBondContact O-N 3.13Å; Y164-I168 HydrophobicContact CD1-CD1 4.11Å; Y164-I168 HydrophobicContact CE1-CD1 3.72Å; Y164-I168 HydrophobicContact CE1-CG1 4.48Å; Y164-I168 HydrophobicContact CE2-CG1 4.42Å; Y164-I168 WeakPolarHBondContact O-CG1 3.31Å; Y164-I168 PolarHBondContact O-N 3.14Å; Y164-C204 WeakPolarHBondContact OH-CB 3.28Å; Y164-M208 HydrophobicContact CD1-CE 4.26Å; Y164-M208 HydrophobicContact CD1-SD 4.38Å; Y164-M208 HydrophobicContact CE1-CE 4.46Å; Y164-M208 HydrophobicContact CE1-CG 4.08Å; Y164-M208 HydrophobicContact CE1-SD 4Å
165	F	97.4	Very high	91.8	Very high	1 Å²	1	46.6 Å²	46.6	0%	0.004	26%	0.262	C	S	.	.	H	α-helix	trans	-65.2	-40.4	174.7	-79.3	0.4	0	0	0	112.7	L161 W167 I168 K169 M208 A217 W218	L161-F165 HydrophobicContact CD1-CD1 4.06Å; L161-F165 HydrophobicContact CD1-CD2 4.25Å; L161-F165 HydrophobicContact CD1-CE1 3.71Å; L161-F165 HydrophobicContact CD1-CE2 3.89Å; L161-F165 HydrophobicContact CD1-CG 4.35Å; L161-F165 HydrophobicContact CD1-CZ 3.62Å; L161-F165 HydrophobicContact CD2-CE2 4.22Å; L161-F165 HydrophobicContact CG-CD2 4.14Å; L161-F165 HydrophobicContact CG-CE2 4.01Å; L161-F165 HydrophobicContact CG-CG 4.49Å; L161-F165 HydrophobicContact CG-CZ 4.27Å; L161-F165 WeakPolarHBondContact O-CB 3.27Å; L161-F165 PolarHBondContact O-N 3.26Å; F165-W167 VanDerWaalsContact C-N 3.3Å; F165-W167 PolarHBondContact O-N 3.2Å; F165-I168 HydrophobicContact CD1-CD1 4.45Å; F165-I168 PolarHBondContact O-N 2.88Å; F165-K169 WeakPolarHBondContact O-CG 3.32Å; F165-K169 PolarHBondContact O-N 3.44Å; F165-M208 HydrophobicContact CE1-CB 4.44Å; F165-M208 HydrophobicContact CE1-CE 3.71Å; F165-M208 HydrophobicContact CE1-CG 4.45Å; F165-M208 HydrophobicContact CZ-CE 4.3Å; F165-A217 HydrophobicContact CE2-CB 3.84Å; F165-W218 HydrophobicContact CB-CE3 4.28Å; F165-W218 HydrophobicContact CB-CZ3 4.12Å; F165-W218 HydrophobicContact CD1-CE3 4.06Å; F165-W218 HydrophobicContact CD1-CZ3 4.27Å; F165-W218 AromaticContact CD2-CE3 3.88Å; F165-W218 HydrophobicContact CD2-CE3 3.88Å; F165-W218 HydrophobicContact CE1-CE3 4.28Å; F165-W218 HydrophobicContact CE2-CB 4.08Å; F165-W218 HydrophobicContact CE2-CE3 4.13Å; F165-W218 AromaticContact CG-CE3 3.83Å; F165-W218 HydrophobicContact CG-CE3 3.83Å; F165-W218 HydrophobicContact CG-CZ3 4.09Å; F165-W218 HydrophobicContact CZ-CB 4.36Å; F165-W218 HydrophobicContact CZ-CE3 4.31Å
166	N	96.4	Very high	89.8	Confident	79 Å²	79	49.8 Å²	49.8	42%	0.422	27%	0.274	S	S	.	.	H	α-helix	trans	-65	-36.9	174.4	-73.6	-27.1	0	0	0	111.7	N162 Y163 K169 T170	N162-N166 VanDerWaalsContact O-CB 3.24Å; N162-N166 WeakPolarHBondContact O-CB 3.16Å; N162-N166 PolarHBondContact O-N 3.44Å; N162-N166 PolarHBondContact O-ND2 2.93Å; N162-N166 VanDerWaalsContact O-ND2 3.1Å; Y163-N166 PolarHBondContact O-N 2.93Å; N166-K169 PolarHBondContact O-N 3.44Å; N166-K169 WeakPolarHBondContact OD1-CE 3.41Å; N166-K169 PolarHBondContact OD1-NZ 3.16Å; N166-T170 WeakPolarHBondContact O-CB 3.31Å; N166-T170 PolarHBondContact O-N 3.34Å; N166-T170 PolarHBondContact O-OG1 3.08Å
167	W	96.1	Very high	87.4	Confident	23 Å²	23	56.7 Å²	56.7	9%	0.087	31%	0.31	C	S	.	.	H	α-helix	trans	-61.2	-50	172.1	-178	92.6	0	0	0	111.1	L130 V138 Y139 A142 Y163 Y164 F165 K169 T170 Q171 V201	L130-W167 HydrophobicContact CD1-CD2 4.22Å; L130-W167 HydrophobicContact CD1-CG 4.2Å; L130-W167 HydrophobicContact CD2-CZ2 4.23Å; V138-W167 HydrophobicContact CG1-CZ2 3.58Å; Y139-W167 AromaticContact CD1-CH2 3.86Å; Y139-W167 HydrophobicContact CD1-CH2 3.86Å; Y139-W167 HydrophobicContact CD1-CZ2 4.26Å; Y139-W167 AromaticContact CE1-CH2 3.98Å; Y139-W167 HydrophobicContact CE1-CH2 3.98Å; Y139-W167 HydrophobicContact CE1-CZ2 4.12Å; A142-W167 HydrophobicContact CB-CH2 3.48Å; A142-W167 VanDerWaalsContact CB-CH2 3.48Å; A142-W167 HydrophobicContact CB-CZ2 4.36Å; A142-W167 HydrophobicContact CB-CZ3 3.56Å; Y163-W167 WeakPolarHBondContact O-CB 3.47Å; Y163-W167 PolarHBondContact O-N 3.39Å; Y164-W167 HydrophobicContact CD2-CE3 4.34Å; Y164-W167 AromaticContact CE2-CE3 3.96Å; Y164-W167 HydrophobicContact CE2-CE3 3.96Å; Y164-W167 HydrophobicContact CE2-CZ3 4.25Å; Y164-W167 WeakPolarHBondContact O-CB 3.37Å; Y164-W167 PolarHBondContact O-N 3.13Å; F165-W167 VanDerWaalsContact C-N 3.3Å; F165-W167 PolarHBondContact O-N 3.2Å; W167-K169 PolarHBondContact O-N 3.05Å; W167-T170 PolarHBondContact O-N 3.48Å; W167-Q171 HydrophobicContact CD2-CG 3.91Å; W167-Q171 HydrophobicContact CE3-CG 4.19Å; W167-Q171 HydrophobicContact CH2-CG 3.93Å; W167-Q171 HydrophobicContact CZ2-CG 3.62Å; W167-Q171 HydrophobicContact CZ3-CG 4.2Å; W167-Q171 VanDerWaalsContact O-CG 3.31Å; W167-Q171 WeakPolarHBondContact O-CG 3.36Å; W167-Q171 PolarHBondContact O-N 3.13Å; W167-V201 HydrophobicContact CH2-CG2 3.95Å; W167-V201 HydrophobicContact CZ3-CG1 4.39Å; W167-V201 HydrophobicContact CZ3-CG2 4.17Å
168	I	96	Very high	85.1	Confident	0 Å²	0	57.7 Å²	57.7	0%	0	31%	0.308	C	S	.	.	H	α-helix	trans	-55.7	-50.9	175.6	-70.6	175.4	0	0	0	110.9	Y164 F165 T170 Q171 L172 V201 L205 W218	Y164-I168 HydrophobicContact CD1-CD1 4.11Å; Y164-I168 HydrophobicContact CE1-CD1 3.72Å; Y164-I168 HydrophobicContact CE1-CG1 4.48Å; Y164-I168 HydrophobicContact CE2-CG1 4.42Å; Y164-I168 WeakPolarHBondContact O-CG1 3.31Å; Y164-I168 PolarHBondContact O-N 3.14Å; F165-I168 HydrophobicContact CD1-CD1 4.45Å; F165-I168 PolarHBondContact O-N 2.88Å; I168-T170 VanDerWaalsContact C-N 3.29Å; I168-T170 PolarHBondContact O-N 3.01Å; I168-Q171 PolarHBondContact O-N 2.96Å; I168-L172 HydrophobicContact CG2-CD1 3.79Å; I168-L172 HydrophobicContact CG2-CG 4.32Å; I168-L172 WeakPolarHBondContact O-CG 3.44Å; I168-L172 PolarHBondContact O-N 3.47Å; I168-V201 HydrophobicContact CB-CG1 4.34Å; I168-V201 HydrophobicContact CG1-CG1 4.38Å; I168-V201 HydrophobicContact CG2-CG1 3.96Å; I168-L205 HydrophobicContact CG2-CB 4.23Å; I168-L205 HydrophobicContact CG2-CD1 4.48Å; I168-W218 HydrophobicContact CB-CZ3 4.48Å; I168-W218 HydrophobicContact CG2-CH2 3.83Å; I168-W218 HydrophobicContact CG2-CZ3 4.12Å
169	K	95.1	Very high	82.7	Confident	41 Å²	41	58.7 Å²	58.7	18%	0.178	32%	0.318	C	S	.	.	H	α-helix	trans	-57.6	-42.5	179.2	-74.9	-174	-67.3	-179.4	0	112	F165 N166 W167 S173 W218 A221 C226	F165-K169 WeakPolarHBondContact O-CG 3.32Å; F165-K169 PolarHBondContact O-N 3.44Å; N166-K169 PolarHBondContact O-N 3.44Å; N166-K169 WeakPolarHBondContact OD1-CE 3.41Å; N166-K169 PolarHBondContact OD1-NZ 3.16Å; W167-K169 PolarHBondContact O-N 3.05Å; K169-S173 WeakPolarHBondContact O-CB 3.42Å; K169-S173 PolarHBondContact O-N 2.9Å; K169-S173 PolarHBondContact O-OG 3.26Å; K169-W218 HydrophobicContact CD-CH2 4.32Å; K169-W218 HydrophobicContact CD-CZ3 4.48Å; K169-W218 HydrophobicContact CG-CH2 3.47Å; K169-W218 VanDerWaalsContact CG-CH2 3.47Å; K169-W218 HydrophobicContact CG-CZ2 4.33Å; K169-W218 HydrophobicContact CG-CZ3 3.86Å; K169-A221 PolarHBondContact NZ-O 3.16Å; K169-C226 HydrophobicContact CG-CB 4.09Å
170	T	92.5	Very high	80	Confident	90 Å²	90	58.6 Å²	58.6	55%	0.552	32%	0.317	S	S	*	.	H	α-helix	trans	-64.6	-46	179	-59.1	0	0	0	0	111.1	N166 W167 I168 S173 S174	N166-T170 WeakPolarHBondContact O-CB 3.31Å; N166-T170 PolarHBondContact O-N 3.34Å; N166-T170 PolarHBondContact O-OG1 3.08Å; W167-T170 PolarHBondContact O-N 3.48Å; I168-T170 VanDerWaalsContact C-N 3.29Å; I168-T170 PolarHBondContact O-N 3.01Å; T170-S173 PolarHBondContact O-N 3.3Å; T170-S174 WeakPolarHBondContact O-CB 3.28Å; T170-S174 PolarHBondContact O-N 3.43Å
171	Q	91.1	Very high	77.2	Confident	42 Å²	42	60.4 Å²	60.4	20%	0.196	35%	0.346	C	S	.	.	H	α-helix	trans	-64.5	-41.8	179	-65.7	-59.1	-42.1	0	0	112	Y139 W167 I168 S174 V201	Y139-Q171 PolarHBondContact OH-OE1 2.95Å; W167-Q171 HydrophobicContact CD2-CG 3.91Å; W167-Q171 HydrophobicContact CE3-CG 4.19Å; W167-Q171 HydrophobicContact CH2-CG 3.93Å; W167-Q171 HydrophobicContact CZ2-CG 3.62Å; W167-Q171 HydrophobicContact CZ3-CG 4.2Å; W167-Q171 VanDerWaalsContact O-CG 3.31Å; W167-Q171 WeakPolarHBondContact O-CG 3.36Å; W167-Q171 PolarHBondContact O-N 3.13Å; I168-Q171 PolarHBondContact O-N 2.96Å; Q171-S174 PolarHBondContact O-OG 3.31Å; Q171-V201 HydrophobicContact CB-CB 4.46Å; Q171-V201 HydrophobicContact CB-CG1 3.94Å; Q171-V201 HydrophobicContact CB-CG2 3.9Å; Q171-V201 HydrophobicContact CG-CG2 4.35Å
172	L	90.1	Very high	74.1	Confident	0 Å²	0	65.6 Å²	65.6	0%	0	38%	0.378	C	S	.	.	H	α-helix	trans	-68	-42.9	176.1	-69.2	177.6	0	0	0	112.2	I168 S174 Q175 V198 V201 L205 V230 M243	I168-L172 HydrophobicContact CG2-CD1 3.79Å; I168-L172 HydrophobicContact CG2-CG 4.32Å; I168-L172 WeakPolarHBondContact O-CG 3.44Å; I168-L172 PolarHBondContact O-N 3.47Å; L172-S174 VanDerWaalsContact C-N 3.3Å; L172-S174 PolarHBondContact O-N 2.97Å; L172-Q175 PolarHBondContact O-N 3.44Å; L172-V198 HydrophobicContact CD2-CG1 3.99Å; L172-V201 HydrophobicContact CD2-CB 4.31Å; L172-V201 HydrophobicContact CD2-CG1 3.94Å; L172-V201 HydrophobicContact CG-CG1 3.87Å; L172-L205 HydrophobicContact CD1-CD2 4.11Å; L172-V230 HydrophobicContact CB-CG2 3.97Å; L172-M243 HydrophobicContact CD2-CE 4.34Å
173	S	84.4	Confident	71.2	Confident	51 Å²	51	66.2 Å²	66.2	36%	0.357	40%	0.395	S	S	.	.	H	α-helix	trans	-72.9	-20.6	-178	-59.4	0	0	0	0	113.5	K169 T170 Q175 K176	K169-S173 WeakPolarHBondContact O-CB 3.42Å; K169-S173 PolarHBondContact O-N 2.9Å; K169-S173 PolarHBondContact O-OG 3.26Å; T170-S173 PolarHBondContact O-N 3.3Å; S173-Q175 PolarHBondContact O-N 2.89Å; S173-K176 WeakPolarHBondContact O-CB 3.3Å; S173-K176 PolarHBondContact O-N 3.44Å
174	S	74.1	Confident	68.2	Low	53 Å²	53	67.6 Å²	67.6	37%	0.371	41%	0.412	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.5	-15.2	175.2	74.6	0	0	0	0	113.7	T170 Q171 L172	T170-S174 WeakPolarHBondContact O-CB 3.28Å; T170-S174 PolarHBondContact O-N 3.43Å; Q171-S174 PolarHBondContact O-OG 3.31Å; L172-S174 VanDerWaalsContact C-N 3.3Å; L172-S174 PolarHBondContact O-N 2.97Å
175	Q	61.6	Low	65.3	Low	38 Å²	38	76.7 Å²	76.7	18%	0.178	45%	0.454	C	S	.	.	T	Hydrogen-bonded Turn	trans	-73.2	-26.6	170.6	-63.6	-140.1	-36	0	0	114	L172 S173 L177 R178 S195 V198	L172-Q175 PolarHBondContact O-N 3.44Å; S173-Q175 PolarHBondContact O-N 2.89Å; Q175-L177 VanDerWaalsContact C-N 3.32Å; Q175-L177 PolarHBondContact O-N 3.14Å; Q175-R178 PolarHBondContact O-N 3.28Å; Q175-S195 PolarHBondContact NE2-OG 2.72Å; Q175-V198 HydrophobicContact CG-CG1 4.3Å; Q175-V198 HydrophobicContact CG-CG2 4.08Å
176	K	50.9	Low	62.2	Low	129 Å²	129	82.5 Å²	82.5	56%	0.561	49%	0.49	S	S	*	.	G	3₁₀ helix	trans	-66	-30.8	-172.9	-144.4	176.8	-170	-177.7	0	113.3	S173 R178	S173-K176 WeakPolarHBondContact O-CB 3.3Å; S173-K176 PolarHBondContact O-N 3.44Å; K176-R178 VanDerWaalsContact C-N 3.28Å; K176-R178 PolarHBondContact O-N 3.21Å
177	L	45.2	Very low	59.3	Low	147 Å²	147	82 Å²	82	77%	0.77	50%	0.503	S	S	*	.	G	3₁₀ helix	trans	-78.2	-4.7	-179.5	-81.1	154.9	0	0	0	114.4	Q175	Q175-L177 VanDerWaalsContact C-N 3.32Å; Q175-L177 PolarHBondContact O-N 3.14Å
178	R	45.4	Very low	56.5	Low	156 Å²	156	87.8 Å²	87.8	59%	0.589	54%	0.541	S	S	*	.	G	3₁₀ helix	trans	-105.5	-7.8	-174.4	-60.2	-168.3	-172.9	-147.2	2.6	114.4	Q175 K176 S194	Q175-R178 PolarHBondContact O-N 3.28Å; K176-R178 VanDerWaalsContact C-N 3.28Å; K176-R178 PolarHBondContact O-N 3.21Å; R178-S194 PolarHBondContact NH2-OG 2.86Å
179	G	41.3	Very low	53.6	Low	68 Å²	68	93.5 Å²	93.5	70%	0.701	58%	0.576	S	S	*	*	S	Bend	trans	-86	-19.3	177.9	0	0	0	0	0	114.9	G181	G179-G181 PolarHBondContact O-N 3.48Å
180	S	38.3	Very low	50.8	Low	89 Å²	89	94.6 Å²	94.6	62%	0.622	59%	0.589	S	S	*	*	S	Bend	trans	-88.9	101	171.5	57.4	0	0	0	0	109.1	V182	S180-V182 PolarHBondContact O-N 3.06Å
181	G	37	Very low	48.3	Very low	80 Å²	80	94.9 Å²	94.9	83%	0.825	59%	0.594	S	S	*	*	S	Bend	trans	-58.3	78.1	-169	0	0	0	0	0	117.2	G179	G179-G181 PolarHBondContact O-N 3.48Å
182	V	33.3	Very low	46.2	Very low	123 Å²	123	95.6 Å²	95.6	75%	0.745	60%	0.604	S	S	*	*			trans	-135.1	84.6	156.8	-168.3	0	0	0	0	108.1	S180 V184	S180-V182 PolarHBondContact O-N 3.06Å; V182-V184 HydrophobicContact CG1-CG2 4.13Å; V182-V184 PolarHBondContact O-N 2.69Å; V182-V184 VanDerWaalsContact O-N 3.11Å
183	A	35.3	Very low	44.2	Very low	99 Å²	99	98.2 Å²	98.2	82%	0.818	62%	0.618	S	S	*	*			trans	-71.4	98.8	166	0	0	0	0	0	108.1	E185	A183-E185 PolarHBondContact O-N 3.16Å
184	V	32.8	Very low	42.7	Very low	110 Å²	110	97.9 Å²	97.9	67%	0.667	62%	0.616	S	S	*	*			trans	-77.3	105.3	162.6	177.6	0	0	0	0	106.9	V182 T186	V182-V184 HydrophobicContact CG1-CG2 4.13Å; V182-V184 PolarHBondContact O-N 2.69Å; V182-V184 VanDerWaalsContact O-N 3.11Å; V184-T186 HydrophobicContact CG1-CG2 4.29Å; V184-T186 PolarHBondContact O-N 3.08Å
185	E	36.5	Very low	42.1	Very low	191 Å²	191	98.3 Å²	98.3	89%	0.893	62%	0.619	S	S	*	*			trans	-60.9	94.9	169	-67.7	-177.5	160.2	0	0	109.6	A183	A183-E185 PolarHBondContact O-N 3.16Å
186	T	32.7	Very low	42.3	Very low	123 Å²	123	99 Å²	99	76%	0.755	62%	0.622	S	S	*	*			trans	-127.4	124.3	158.1	43.2	0	0	0	0	107.2	V184	V184-T186 HydrophobicContact CG1-CG2 4.29Å; V184-T186 PolarHBondContact O-N 3.08Å
187	G	35.2	Very low	43.7	Very low	68 Å²	68	93.1 Å²	93.1	70%	0.701	60%	0.596	S	S	*	*			trans	-73.9	169.5	-153.3	0	0	0	0	0	116.6
188	T	37.5	Very low	45.7	Very low	145 Å²	145	86.3 Å²	86.3	89%	0.89	56%	0.561	S	S	*	*	S	Bend	trans	88.8	37.4	157.6	67.9	0	0	0	0	120.5
189	V	36.4	Very low	47.7	Very low	121 Å²	121	81.5 Å²	81.5	73%	0.733	55%	0.545	S	S	*	.	S	Bend	trans	-146.5	127.7	137.8	-170.8	0	0	0	0	107.2	S191	V189-S191 PolarHBondContact O-N 2.88Å; V189-S191 VanDerWaalsContact O-N 3.14Å
190	S	36.2	Very low	50	Low	63 Å²	63	78.3 Å²	78.3	44%	0.441	51%	0.512	S	S	.	.			trans	-51.3	122.5	173.7	39.9	0	0	0	0	109.6	S192 D193	S190-S192 PolarHBondContact O-N 2.89Å; S190-D193 PolarHBondContact O-N 3.42Å; S190-D193 VanDerWaalsContact O-N 3.09Å; S190-D193 VanDerWaalsContact OG-CG 3.29Å; S190-D193 PolarHBondContact OG-OD1 3.1Å; S190-D193 PolarHBondContact OG-OD2 3.3Å
191	S	38.8	Very low	52.7	Low	96 Å²	96	74.1 Å²	74.1	67%	0.671	48%	0.483	S	S	*	.	H	α-helix	trans	-56.6	-16.1	-176.7	48.2	0	0	0	0	114	V189	V189-S191 PolarHBondContact O-N 2.88Å; V189-S191 VanDerWaalsContact O-N 3.14Å
192	S	47.9	Very low	55.3	Low	58 Å²	58	70.3 Å²	70.3	41%	0.406	44%	0.444	S	S	.	.	H	α-helix	trans	-71.6	-34.4	175.5	54.1	0	0	0	0	114.6	S190 S195 Q196	S190-S192 PolarHBondContact O-N 2.89Å; S192-S195 PolarHBondContact O-N 3Å; S192-Q196 VanDerWaalsContact O-CG 3.23Å; S192-Q196 WeakPolarHBondContact O-CG 3.27Å; S192-Q196 PolarHBondContact O-N 2.89Å; S192-Q196 PolarHBondContact O-NE2 3.44Å
193	D	48.1	Very low	58.2	Low	54 Å²	54	65.4 Å²	65.4	29%	0.289	42%	0.418	S	S	.	.	H	α-helix	trans	-80.5	-32.7	-160.2	-68.7	9.8	0	0	0	112.5	S190 Q196 Y197	S190-D193 PolarHBondContact O-N 3.42Å; S190-D193 VanDerWaalsContact O-N 3.09Å; S190-D193 VanDerWaalsContact OG-CG 3.29Å; S190-D193 PolarHBondContact OG-OD1 3.1Å; S190-D193 PolarHBondContact OG-OD2 3.3Å; D193-Q196 WeakPolarHBondContact O-CB 3.39Å; D193-Q196 PolarHBondContact O-N 3.16Å; D193-Y197 WeakPolarHBondContact O-CD2 3.45Å; D193-Y197 VanDerWaalsContact O-CE2 3.31Å; D193-Y197 WeakPolarHBondContact O-CE2 3.04Å
194	S	51.9	Low	61.1	Low	44 Å²	44	60.9 Å²	60.9	31%	0.308	38%	0.38	S	S	.	.	H	α-helix	trans	-68.4	-35.4	175.2	57.5	0	0	0	0	113.1	R178 Q196	R178-S194 PolarHBondContact NH2-OG 2.86Å; S194-Q196 PolarHBondContact O-N 3.2Å
195	S	60.9	Low	64.1	Low	62 Å²	62	55.6 Å²	55.6	43%	0.434	35%	0.348	S	S	.	.	H	α-helix	trans	-69.3	-23	176.6	-175	0	0	0	0	112.7	Q175 S192	Q175-S195 PolarHBondContact NE2-OG 2.72Å; S192-S195 PolarHBondContact O-N 3Å
196	Q	66.6	Low	66.9	Low	53 Å²	53	47.6 Å²	47.6	25%	0.248	31%	0.311	C	S	.	.	H	α-helix	trans	-73.7	-32.8	-176.8	-74.3	163.5	11.3	0	0	112.6	I18 S192 D193 S194 V198	I18-Q196 HydrophobicContact CB-CB 4.38Å; I18-Q196 HydrophobicContact CD1-CB 3.71Å; I18-Q196 VanDerWaalsContact CD1-CD 3.42Å; I18-Q196 HydrophobicContact CD1-CG 3.45Å; I18-Q196 VanDerWaalsContact CD1-CG 3.45Å; I18-Q196 HydrophobicContact CG1-CB 4.23Å; I18-Q196 HydrophobicContact CG1-CG 4.21Å; I18-Q196 VanDerWaalsContact CG1-OE1 3.24Å; S192-Q196 VanDerWaalsContact O-CG 3.23Å; S192-Q196 WeakPolarHBondContact O-CG 3.27Å; S192-Q196 PolarHBondContact O-N 2.89Å; S192-Q196 PolarHBondContact O-NE2 3.44Å; D193-Q196 WeakPolarHBondContact O-CB 3.39Å; D193-Q196 PolarHBondContact O-N 3.16Å; S194-Q196 PolarHBondContact O-N 3.2Å; Q196-V198 VanDerWaalsContact C-N 3.35Å
197	Y	81.4	Confident	69.9	Low	5 Å²	5	42.8 Å²	42.8	2%	0.02	28%	0.28	C	S	.	.	H	α-helix	trans	-82	-12.2	178	-61.6	-82.8	0	0	0	113.7	I18 I19 K22 P135 Y139 D193 Q199 C200 V201	I18-Y197 HydrophobicContact CG2-CE1 4.46Å; I19-Y197 HydrophobicContact CD1-CD1 3.84Å; I19-Y197 HydrophobicContact CD1-CE1 4.34Å; I19-Y197 HydrophobicContact CG1-CD1 3.61Å; I19-Y197 HydrophobicContact CG1-CE1 3.73Å; K22-Y197 WeakPolarHBondContact CD-OH 3.47Å; K22-Y197 VanDerWaalsContact CE-OH 3.3Å; K22-Y197 WeakPolarHBondContact CE-OH 3.41Å; K22-Y197 PolarHBondContact NZ-OH 3.22Å; P135-Y197 HydrophobicContact CB-CD2 4.48Å; P135-Y197 HydrophobicContact CB-CE2 3.97Å; Y139-Y197 HydrophobicContact CD1-CG 4.49Å; Y139-Y197 AromaticContact CD2-CD1 3.14Å; Y139-Y197 HydrophobicContact CD2-CD1 3.14Å; Y139-Y197 AromaticContact CD2-CD2 3.84Å; Y139-Y197 HydrophobicContact CD2-CD2 3.84Å; Y139-Y197 AromaticContact CD2-CE1 3.83Å; Y139-Y197 HydrophobicContact CD2-CE1 3.83Å; Y139-Y197 HydrophobicContact CD2-CE2 4.45Å; Y139-Y197 AromaticContact CD2-CG 3.16Å; Y139-Y197 HydrophobicContact CD2-CG 3.16Å; Y139-Y197 AromaticContact CE2-CD1 3.78Å; Y139-Y197 HydrophobicContact CE2-CD1 3.78Å; Y139-Y197 AromaticContact CE2-CD2 3.59Å; Y139-Y197 HydrophobicContact CE2-CD2 3.59Å; Y139-Y197 HydrophobicContact CE2-CE2 4.39Å; Y139-Y197 AromaticContact CE2-CG 3.25Å; Y139-Y197 HydrophobicContact CE2-CG 3.25Å; Y139-Y197 AromaticContact CG-CD1 3.66Å; Y139-Y197 HydrophobicContact CG-CD1 3.66Å; Y139-Y197 AromaticContact CG-CG 3.86Å; Y139-Y197 HydrophobicContact CG-CG 3.86Å; Y139-Y197 AromaticContact CZ-CG 4Å; D193-Y197 WeakPolarHBondContact O-CD2 3.45Å; D193-Y197 VanDerWaalsContact O-CE2 3.31Å; D193-Y197 WeakPolarHBondContact O-CE2 3.04Å; Y197-Q199 PolarHBondContact O-N 3.23Å; Y197-C200 WeakPolarHBondContact O-CA 3.4Å; Y197-C200 WeakPolarHBondContact O-CB 3.42Å; Y197-C200 PolarHBondContact O-N 3.13Å; Y197-V201 PolarHBondContact O-N 3.33Å; Y197-V201 VanDerWaalsContact O-N 3.13Å
198	V	86.8	Confident	72.8	Confident	4 Å²	4	39.6 Å²	39.6	2%	0.024	25%	0.247	C	C	.	.	H	α-helix	trans	-60	-34.5	178	177.8	0	0	0	0	111.4	L172 Q175 Q196 C200 V201 A202 L239	L172-V198 HydrophobicContact CD2-CG1 3.99Å; Q175-V198 HydrophobicContact CG-CG1 4.3Å; Q175-V198 HydrophobicContact CG-CG2 4.08Å; Q196-V198 VanDerWaalsContact C-N 3.35Å; V198-C200 VanDerWaalsContact C-N 3.26Å; V198-C200 PolarHBondContact O-N 3.37Å; V198-V201 PolarHBondContact O-N 3.43Å; V198-A202 WeakPolarHBondContact O-CB 3.43Å; V198-A202 PolarHBondContact O-N 3.01Å; V198-L239 HydrophobicContact CG1-CD1 4.03Å; V198-L239 HydrophobicContact CG1-CD2 3.79Å
199	Q	87.6	Confident	75.6	Confident	56 Å²	56	32.7 Å²	32.7	26%	0.262	21%	0.205	S	C	.	.	H	α-helix	trans	-64.5	-30.9	173.8	-63.9	179.7	7.9	0	0	112.8	Y197 G203 Q238 Q242	Y197-Q199 PolarHBondContact O-N 3.23Å; Q199-G203 PolarHBondContact O-N 3.15Å; Q199-Q238 HydrophobicContact CG-CG 4.16Å; Q199-Q242 PolarHBondContact O-NE2 2.95Å; Q199-Q242 PolarHBondContact O-OE1 3.31Å
200	C	89.8	Confident	78.4	Confident	1 Å²	1	30.8 Å²	30.8	1%	0.007	18%	0.184	C	C	.	.	H	α-helix	trans	-67.7	-46.8	172.7	175.7	0	0	0	0	111.1	I19 R143 Y197 V198 A202 G203 C204	I19-C200 HydrophobicContact CD1-CB 3.29Å; I19-C200 WeakPolarHBondContact CD1-SG 3.33Å; I19-C200 HydrophobicContact CG1-CB 4.41Å; R143-C200 WeakPolarHBondContact CD-SG 3.12Å; R143-C200 WeakPolarHBondContact CG-SG 3.44Å; Y197-C200 WeakPolarHBondContact O-CA 3.4Å; Y197-C200 WeakPolarHBondContact O-CB 3.42Å; Y197-C200 PolarHBondContact O-N 3.13Å; V198-C200 VanDerWaalsContact C-N 3.26Å; V198-C200 PolarHBondContact O-N 3.37Å; C200-A202 VanDerWaalsContact C-N 3.31Å; C200-A202 PolarHBondContact O-N 3.43Å; C200-G203 CarbonylContact O-C 3.11Å; C200-G203 WeakPolarHBondContact O-CA 3.23Å; C200-G203 PolarHBondContact O-N 3.34Å; C200-C204 PolarHBondContact O-N 3.11Å; C200-C204 PolarHBondContact O-SG 3.11Å
201	V	93.3	Very high	81.2	Confident	1 Å²	1	29.1 Å²	29.1	1%	0.006	17%	0.171	C	C	.	.	H	α-helix	trans	-60.7	-43.4	177.6	179	0	0	0	0	110.7	Y139 W167 I168 Q171 L172 Y197 V198 G203 C204 L205	Y139-V201 HydrophobicContact CD1-CG2 3.72Å; Y139-V201 HydrophobicContact CE1-CG2 3.47Å; Y139-V201 VanDerWaalsContact CE1-CG2 3.47Å; W167-V201 HydrophobicContact CH2-CG2 3.95Å; W167-V201 HydrophobicContact CZ3-CG1 4.39Å; W167-V201 HydrophobicContact CZ3-CG2 4.17Å; I168-V201 HydrophobicContact CB-CG1 4.34Å; I168-V201 HydrophobicContact CG1-CG1 4.38Å; I168-V201 HydrophobicContact CG2-CG1 3.96Å; Q171-V201 HydrophobicContact CB-CB 4.46Å; Q171-V201 HydrophobicContact CB-CG1 3.94Å; Q171-V201 HydrophobicContact CB-CG2 3.9Å; Q171-V201 HydrophobicContact CG-CG2 4.35Å; L172-V201 HydrophobicContact CD2-CB 4.31Å; L172-V201 HydrophobicContact CD2-CG1 3.94Å; L172-V201 HydrophobicContact CG-CG1 3.87Å; Y197-V201 PolarHBondContact O-N 3.33Å; Y197-V201 VanDerWaalsContact O-N 3.13Å; V198-V201 PolarHBondContact O-N 3.43Å; V201-G203 VanDerWaalsContact C-N 3.31Å; V201-G203 PolarHBondContact O-N 3.29Å; V201-C204 WeakPolarHBondContact O-CB 3.29Å; V201-C204 PolarHBondContact O-N 3.22Å; V201-C204 VanDerWaalsContact O-N 3.14Å; V201-L205 PolarHBondContact O-N 3.35Å
202	A	93.3	Very high	83.8	Confident	0 Å²	0	27.8 Å²	27.8	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-58.1	-43	172.6	0	0	0	0	0	111.9	V198 C200 C204 L205 Q206 L239 Q242 M243	V198-A202 WeakPolarHBondContact O-CB 3.43Å; V198-A202 PolarHBondContact O-N 3.01Å; C200-A202 VanDerWaalsContact C-N 3.31Å; C200-A202 PolarHBondContact O-N 3.43Å; A202-C204 VanDerWaalsContact C-N 3.34Å; A202-C204 PolarHBondContact O-N 3.25Å; A202-L205 PolarHBondContact O-N 3.37Å; A202-Q206 WeakPolarHBondContact O-CG 3.29Å; A202-Q206 PolarHBondContact O-N 2.91Å; A202-L239 HydrophobicContact CB-CD1 3.72Å; A202-Q242 HydrophobicContact CB-CB 3.82Å; A202-Q242 HydrophobicContact CB-CG 4.41Å; A202-M243 HydrophobicContact CB-CE 3.36Å
203	G	93.3	Very high	86	Confident	20 Å²	20	29.8 Å²	29.8	21%	0.206	16%	0.159	C	C	.	.	H	α-helix	trans	-62.8	-37.4	173.8	0	0	0	0	0	113.6	Q199 C200 V201 Q206 L207	Q199-G203 PolarHBondContact O-N 3.15Å; C200-G203 CarbonylContact O-C 3.11Å; C200-G203 WeakPolarHBondContact O-CA 3.23Å; C200-G203 PolarHBondContact O-N 3.34Å; V201-G203 VanDerWaalsContact C-N 3.31Å; V201-G203 PolarHBondContact O-N 3.29Å; G203-Q206 PolarHBondContact O-N 3.38Å; G203-L207 WeakPolarHBondContact O-CB 3.32Å; G203-L207 PolarHBondContact O-N 3.37Å
204	C	95.5	Very high	88.3	Confident	3 Å²	3	27.3 Å²	27.3	2%	0.02	15%	0.146	C	C	.	.	H	α-helix	trans	-63.1	-45.4	174.1	-63.4	0	0	0	0	110.8	A146 Y164 C200 V201 A202 L207 M208	A146-C204 HydrophobicContact CB-CB 3.94Å; Y164-C204 WeakPolarHBondContact OH-CB 3.28Å; C200-C204 PolarHBondContact O-N 3.11Å; C200-C204 PolarHBondContact O-SG 3.11Å; V201-C204 WeakPolarHBondContact O-CB 3.29Å; V201-C204 PolarHBondContact O-N 3.22Å; V201-C204 VanDerWaalsContact O-N 3.14Å; A202-C204 VanDerWaalsContact C-N 3.34Å; A202-C204 PolarHBondContact O-N 3.25Å; C204-L207 PolarHBondContact O-N 3.39Å; C204-M208 WeakPolarHBondContact O-CG 3.37Å; C204-M208 PolarHBondContact O-N 3.37Å
205	L	97.3	Very high	90.4	Very high	0 Å²	0	26.2 Å²	26.2	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-60.4	-48.1	175.3	178.7	62.4	0	0	0	111.5	I168 L172 V201 A202 L207 M208 L209 W218 I227	I168-L205 HydrophobicContact CG2-CB 4.23Å; I168-L205 HydrophobicContact CG2-CD1 4.48Å; L172-L205 HydrophobicContact CD1-CD2 4.11Å; V201-L205 PolarHBondContact O-N 3.35Å; A202-L205 PolarHBondContact O-N 3.37Å; L205-L207 PolarHBondContact O-N 2.69Å; L205-M208 PolarHBondContact O-N 2.85Å; L205-L209 HydrophobicContact CD1-CD1 3.8Å; L205-L209 HydrophobicContact CD1-CD2 4.3Å; L205-L209 HydrophobicContact CD1-CG 3.83Å; L205-L209 HydrophobicContact CD2-CD1 4.45Å; L205-L209 HydrophobicContact CG-CD1 3.82Å; L205-L209 HydrophobicContact CG-CG 4.21Å; L205-L209 WeakPolarHBondContact O-CB 3.23Å; L205-L209 VanDerWaalsContact O-CG 3.29Å; L205-L209 WeakPolarHBondContact O-CG 3.48Å; L205-L209 PolarHBondContact O-N 3.37Å; L205-W218 HydrophobicContact CD1-CD2 3.75Å; L205-W218 HydrophobicContact CD1-CE3 3.83Å; L205-W218 HydrophobicContact CD1-CG 4.42Å; L205-W218 HydrophobicContact CD1-CH2 3.92Å; L205-W218 HydrophobicContact CD1-CZ2 3.84Å; L205-W218 HydrophobicContact CD1-CZ3 3.92Å; L205-W218 HydrophobicContact CD2-CH2 4.24Å; L205-W218 HydrophobicContact CD2-CZ2 3.75Å; L205-W218 HydrophobicContact CG-CZ2 4.47Å; L205-I227 HydrophobicContact CD2-CD1 4.22Å; L205-I227 HydrophobicContact CD2-CG1 4.14Å
206	Q	95.6	Very high	92.1	Very high	23 Å²	23	25.9 Å²	25.9	11%	0.107	13%	0.126	C	C	.	.	H	α-helix	trans	-56.1	-39.9	177.3	-71.9	176	-66.3	0	0	112.1	A202 G203 R210 Q242 F245 L249	A202-Q206 WeakPolarHBondContact O-CG 3.29Å; A202-Q206 PolarHBondContact O-N 2.91Å; G203-Q206 PolarHBondContact O-N 3.38Å; Q206-R210 WeakPolarHBondContact O-CG 3.42Å; Q206-R210 PolarHBondContact O-N 2.96Å; Q206-Q242 HydrophobicContact CG-CB 4.45Å; Q206-Q242 VanDerWaalsContact OE1-CG 3.3Å; Q206-F245 HydrophobicContact CB-CD1 4.39Å; Q206-F245 HydrophobicContact CG-CD1 4.02Å; Q206-F245 VanDerWaalsContact NE2-CB 3.26Å; Q206-L249 WeakPolarHBondContact O-CD1 3.4Å
207	L	94.8	Very high	93.5	Very high	22 Å²	22	24.4 Å²	24.4	12%	0.115	12%	0.123	C	C	.	.	H	α-helix	trans	-69	-45.1	179.6	-175.6	56	0	0	0	111.6	A146 K147 A150 G203 C204 L205 L209 R210	A146-L207 HydrophobicContact CB-CB 4.38Å; A146-L207 HydrophobicContact CB-CD2 3.98Å; A146-L207 HydrophobicContact CB-CG 4.41Å; K147-L207 HydrophobicContact CB-CD2 4.39Å; K147-L207 HydrophobicContact CG-CD2 3.78Å; A150-L207 HydrophobicContact CB-CD1 3.56Å; A150-L207 HydrophobicContact CB-CD2 4.4Å; A150-L207 HydrophobicContact CB-CG 3.53Å; A150-L207 WeakPolarHBondContact CB-O 3.34Å; G203-L207 WeakPolarHBondContact O-CB 3.32Å; G203-L207 PolarHBondContact O-N 3.37Å; C204-L207 PolarHBondContact O-N 3.39Å; L205-L207 PolarHBondContact O-N 2.69Å; L207-L209 PolarHBondContact O-N 3.08Å; L207-R210 WeakPolarHBondContact O-CB 3.39Å; L207-R210 PolarHBondContact O-N 2.74Å
208	M	96.3	Very high	94.2	Very high	0 Å²	0	24.1 Å²	24.1	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-56.6	-49.5	173.5	-68.3	-64.9	-69.6	0	0	110.9	A146 A149 L161 Y164 F165 C204 L205 R210 V211 Y214	A146-M208 HydrophobicContact CB-CG 4.38Å; A146-M208 HydrophobicContact CB-SD 4.41Å; A149-M208 HydrophobicContact CB-CE 3.87Å; A149-M208 HydrophobicContact CB-SD 3.36Å; A149-M208 WeakPolarHBondContact CB-SD 3.29Å; L161-M208 HydrophobicContact CD1-CE 3.87Å; Y164-M208 HydrophobicContact CD1-CE 4.26Å; Y164-M208 HydrophobicContact CD1-SD 4.38Å; Y164-M208 HydrophobicContact CE1-CE 4.46Å; Y164-M208 HydrophobicContact CE1-CG 4.08Å; Y164-M208 HydrophobicContact CE1-SD 4Å; F165-M208 HydrophobicContact CE1-CB 4.44Å; F165-M208 HydrophobicContact CE1-CE 3.71Å; F165-M208 HydrophobicContact CE1-CG 4.45Å; F165-M208 HydrophobicContact CZ-CE 4.3Å; C204-M208 WeakPolarHBondContact O-CG 3.37Å; C204-M208 PolarHBondContact O-N 3.37Å; L205-M208 PolarHBondContact O-N 2.85Å; M208-R210 PolarHBondContact O-N 3.12Å; M208-V211 PolarHBondContact O-N 2.94Å; M208-V211 VanDerWaalsContact O-N 3.08Å; M208-Y214 HydrophobicContact CB-CD2 4.39Å; M208-Y214 HydrophobicContact CE-CD1 4.09Å; M208-Y214 HydrophobicContact CE-CD2 3.62Å; M208-Y214 HydrophobicContact CE-CE1 4.18Å; M208-Y214 HydrophobicContact CE-CE2 3.75Å; M208-Y214 HydrophobicContact CE-CG 3.85Å; M208-Y214 WeakPolarHBondContact O-CD2 3.45Å; M208-Y214 HydrophobicContact SD-CD2 4.25Å; M208-Y214 HydrophobicContact SD-CE2 4.28Å
209	L	96.3	Very high	94.5	Very high	0 Å²	0	24.8 Å²	24.8	0%	0	13%	0.126	C	C	.	.	T	Hydrogen-bonded Turn	trans	-68.2	-1.5	-176.7	-65	-179	0	0	0	114.1	L205 L207 V211 R215 W218 L249 L250	L205-L209 HydrophobicContact CD1-CD1 3.8Å; L205-L209 HydrophobicContact CD1-CD2 4.3Å; L205-L209 HydrophobicContact CD1-CG 3.83Å; L205-L209 HydrophobicContact CD2-CD1 4.45Å; L205-L209 HydrophobicContact CG-CD1 3.82Å; L205-L209 HydrophobicContact CG-CG 4.21Å; L205-L209 WeakPolarHBondContact O-CB 3.23Å; L205-L209 VanDerWaalsContact O-CG 3.29Å; L205-L209 WeakPolarHBondContact O-CG 3.48Å; L205-L209 PolarHBondContact O-N 3.37Å; L207-L209 PolarHBondContact O-N 3.08Å; L209-V211 VanDerWaalsContact C-N 3.28Å; L209-R215 HydrophobicContact CB-CG 4.46Å; L209-R215 HydrophobicContact CD2-CG 4.27Å; L209-R215 WeakPolarHBondContact O-CG 3.33Å; L209-R215 PolarHBondContact O-NE 2.92Å; L209-W218 HydrophobicContact CD2-CB 3.77Å; L209-W218 HydrophobicContact CD2-CG 3.96Å; L209-L249 HydrophobicContact CB-CB 4.27Å; L209-L249 HydrophobicContact CB-CD1 3.61Å; L209-L250 HydrophobicContact CD1-CD2 4.06Å; L209-L250 HydrophobicContact CD1-CG 4.48Å; L209-L250 HydrophobicContact CD2-CD2 3.84Å; L209-L250 HydrophobicContact CG-CD2 4.48Å
210	R	94.4	Very high	94.8	Very high	82 Å²	82	29.8 Å²	29.8	31%	0.309	15%	0.149	S	C	.	.	T	Hydrogen-bonded Turn	trans	-69.3	-30.3	168.9	-65	-173.9	-176.9	-174.9	-1.7	112	Q206 L207 M208 R215	Q206-R210 WeakPolarHBondContact O-CG 3.42Å; Q206-R210 PolarHBondContact O-N 2.96Å; L207-R210 WeakPolarHBondContact O-CB 3.39Å; L207-R210 PolarHBondContact O-N 2.74Å; M208-R210 PolarHBondContact O-N 3.12Å; R210-R215 PolarHBondContact O-NH2 2.91Å; R210-R215 VanDerWaalsContact O-NH2 3.07Å
211	V	94.6	Very high	95	Very high	27 Å²	27	30.9 Å²	30.9	16%	0.164	16%	0.158	C	C	.	.	S	Bend	trans	-85.5	131.5	177.8	-179.7	0	0	0	0	109.2	A150 L155 M208 L209 E213 Y214 R215	A150-V211 HydrophobicContact CB-CG2 4.42Å; L155-V211 HydrophobicContact CD2-CG1 3.84Å; M208-V211 PolarHBondContact O-N 2.94Å; M208-V211 VanDerWaalsContact O-N 3.08Å; L209-V211 VanDerWaalsContact C-N 3.28Å; V211-E213 HydrophobicContact CG1-CB 4.44Å; V211-E213 WeakPolarHBondContact CG1-OE2 3.38Å; V211-E213 PolarHBondContact O-N 2.9Å; V211-Y214 HydrophobicContact CB-CD2 3.52Å; V211-Y214 HydrophobicContact CB-CE2 3.9Å; V211-Y214 HydrophobicContact CB-CG 4.24Å; V211-Y214 HydrophobicContact CG1-CD2 3.91Å; V211-Y214 HydrophobicContact CG1-CE2 4.01Å; V211-Y214 HydrophobicContact CG1-CG 4.39Å; V211-Y214 HydrophobicContact CG2-CD2 3.98Å; V211-Y214 HydrophobicContact CG2-CE2 3.97Å; V211-Y214 PolarHBondContact O-N 3.08Å; V211-R215 WeakPolarHBondContact O-CG 3.36Å; V211-R215 PolarHBondContact O-N 2.87Å
212	N	93.9	Very high	95	Very high	68 Å²	68	34.5 Å²	34.5	36%	0.364	18%	0.177	S	C	.	.	H	α-helix	trans	-64.4	-42	-170.3	-174.8	58.2	0	0	0	112.2	Y214 R215 F216	N212-Y214 VanDerWaalsContact C-N 3.31Å; N212-Y214 PolarHBondContact O-N 3.21Å; N212-R215 VanDerWaalsContact O-CB 3.25Å; N212-R215 WeakPolarHBondContact O-CB 3.41Å; N212-R215 PolarHBondContact O-N 3.4Å; N212-F216 WeakPolarHBondContact O-CD2 3.4Å; N212-F216 PolarHBondContact O-N 3.21Å
213	E	95.3	Very high	95	Very high	100 Å²	100	34.5 Å²	34.5	47%	0.467	18%	0.177	S	C	.	.	H	α-helix	trans	-59.9	-41.2	-178.8	-64.5	78	-172.8	0	0	111.4	L155 V211 R215 F216 A217	L155-E213 HydrophobicContact CD1-CB 4.07Å; L155-E213 HydrophobicContact CD1-CG 3.72Å; V211-E213 HydrophobicContact CG1-CB 4.44Å; V211-E213 WeakPolarHBondContact CG1-OE2 3.38Å; V211-E213 PolarHBondContact O-N 2.9Å; E213-R215 VanDerWaalsContact C-N 3.28Å; E213-R215 PolarHBondContact O-N 2.91Å; E213-F216 PolarHBondContact O-N 3.24Å; E213-A217 PolarHBondContact O-N 3.21Å; E213-A217 VanDerWaalsContact O-N 3.11Å
214	Y	96.8	Very high	95.1	Very high	3 Å²	3	33.5 Å²	33.5	1%	0.012	17%	0.167	C	C	.	.	H	α-helix	trans	-69.3	-23.9	176.2	-61.5	-30.7	0	0	0	113.3	A149 L155 M156 L161 M208 V211 N212 W218	A149-Y214 HydrophobicContact CB-CE2 3.9Å; A149-Y214 WeakPolarHBondContact O-CE2 3.44Å; A149-Y214 PolarHBondContact O-OH 3.28Å; L155-Y214 WeakPolarHBondContact CA-OH 3.35Å; L155-Y214 HydrophobicContact CD2-CE1 4.32Å; L155-Y214 HydrophobicContact CD2-CE2 4.49Å; M156-Y214 HydrophobicContact CB-CE1 4.3Å; M156-Y214 PolarHBondContact N-OH 3.22Å; M156-Y214 WeakPolarHBondContact O-CE1 3.32Å; L161-Y214 HydrophobicContact CD1-CD1 3.89Å; L161-Y214 HydrophobicContact CD1-CE1 4.02Å; L161-Y214 HydrophobicContact CD2-CD1 4.24Å; M208-Y214 HydrophobicContact CB-CD2 4.39Å; M208-Y214 HydrophobicContact CE-CD1 4.09Å; M208-Y214 HydrophobicContact CE-CD2 3.62Å; M208-Y214 HydrophobicContact CE-CE1 4.18Å; M208-Y214 HydrophobicContact CE-CE2 3.75Å; M208-Y214 HydrophobicContact CE-CG 3.85Å; M208-Y214 WeakPolarHBondContact O-CD2 3.45Å; M208-Y214 HydrophobicContact SD-CD2 4.25Å; M208-Y214 HydrophobicContact SD-CE2 4.28Å; V211-Y214 HydrophobicContact CB-CD2 3.52Å; V211-Y214 HydrophobicContact CB-CE2 3.9Å; V211-Y214 HydrophobicContact CB-CG 4.24Å; V211-Y214 HydrophobicContact CG1-CD2 3.91Å; V211-Y214 HydrophobicContact CG1-CE2 4.01Å; V211-Y214 HydrophobicContact CG1-CG 4.39Å; V211-Y214 HydrophobicContact CG2-CD2 3.98Å; V211-Y214 HydrophobicContact CG2-CE2 3.97Å; V211-Y214 PolarHBondContact O-N 3.08Å; N212-Y214 VanDerWaalsContact C-N 3.31Å; N212-Y214 PolarHBondContact O-N 3.21Å; Y214-W218 VanDerWaalsContact O-CB 3.23Å; Y214-W218 WeakPolarHBondContact O-CB 3.32Å; Y214-W218 PolarHBondContact O-N 2.99Å
215	R	95.8	Very high	95	Very high	20 Å²	20	37.1 Å²	37.1	8%	0.075	19%	0.187	C	C	.	.	H	α-helix	trans	-67.2	-46.3	174.2	-59.4	175.4	-169.3	167.5	3.1	111.2	L209 R210 V211 N212 E213 W218 V219 L250 M256	L209-R215 HydrophobicContact CB-CG 4.46Å; L209-R215 HydrophobicContact CD2-CG 4.27Å; L209-R215 WeakPolarHBondContact O-CG 3.33Å; L209-R215 PolarHBondContact O-NE 2.92Å; R210-R215 PolarHBondContact O-NH2 2.91Å; R210-R215 VanDerWaalsContact O-NH2 3.07Å; V211-R215 WeakPolarHBondContact O-CG 3.36Å; V211-R215 PolarHBondContact O-N 2.87Å; N212-R215 VanDerWaalsContact O-CB 3.25Å; N212-R215 WeakPolarHBondContact O-CB 3.41Å; N212-R215 PolarHBondContact O-N 3.4Å; E213-R215 VanDerWaalsContact C-N 3.28Å; E213-R215 PolarHBondContact O-N 2.91Å; R215-W218 PolarHBondContact O-N 3.25Å; R215-V219 WeakPolarHBondContact O-CG2 3.32Å; R215-V219 PolarHBondContact O-N 3.27Å; R215-V219 VanDerWaalsContact O-N 3.12Å; R215-L250 HydrophobicContact CB-CD2 3.97Å; R215-L250 HydrophobicContact CG-CD2 4.24Å; R215-M256 HydrophobicContact CB-CE 3.52Å; R215-M256 HydrophobicContact CB-SD 3.66Å
216	F	94.9	Very high	94.9	Very high	56 Å²	56	37.7 Å²	37.7	25%	0.246	19%	0.19	C	C	.	.	H	α-helix	trans	-62.9	-49.6	176.4	-74.5	-84.9	0	0	0	110.9	N212 E213 W218 V219 E220 Q255 M256	N212-F216 WeakPolarHBondContact O-CD2 3.4Å; N212-F216 PolarHBondContact O-N 3.21Å; E213-F216 PolarHBondContact O-N 3.24Å; F216-W218 VanDerWaalsContact C-N 3.25Å; F216-W218 PolarHBondContact O-N 2.9Å; F216-V219 PolarHBondContact O-N 3.47Å; F216-V219 VanDerWaalsContact O-N 3.11Å; F216-E220 WeakPolarHBondContact O-CG 3.4Å; F216-E220 PolarHBondContact O-N 3.23Å; F216-Q255 HydrophobicContact CE1-CB 4.32Å; F216-M256 HydrophobicContact CD1-CG 4.46Å; F216-M256 HydrophobicContact CE1-CG 4.09Å; F216-M256 HydrophobicContact CE2-SD 4.44Å; F216-M256 HydrophobicContact CZ-CG 4.24Å
217	A	96.1	Very high	94.8	Very high	21 Å²	21	36.6 Å²	36.6	17%	0.174	19%	0.185	C	C	.	.	H	α-helix	trans	-58.7	-36.6	177.7	0	0	0	0	0	112.7	L161 F165 E213 A221	L161-A217 HydrophobicContact CD2-CB 3.72Å; F165-A217 HydrophobicContact CE2-CB 3.84Å; E213-A217 PolarHBondContact O-N 3.21Å; E213-A217 VanDerWaalsContact O-N 3.11Å; A217-A221 VanDerWaalsContact O-CB 3.23Å; A217-A221 WeakPolarHBondContact O-CB 3.47Å; A217-A221 PolarHBondContact O-N 3.47Å
218	W	96.6	Very high	94.8	Very high	0 Å²	0	36.2 Å²	36.2	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-66.5	-41.8	176.7	-177.9	-105.1	0	0	0	112.4	F165 I168 K169 L205 L209 Y214 R215 F216 A221 G223 C226 I227	F165-W218 HydrophobicContact CB-CE3 4.28Å; F165-W218 HydrophobicContact CB-CZ3 4.12Å; F165-W218 HydrophobicContact CD1-CE3 4.06Å; F165-W218 HydrophobicContact CD1-CZ3 4.27Å; F165-W218 AromaticContact CD2-CE3 3.88Å; F165-W218 HydrophobicContact CD2-CE3 3.88Å; F165-W218 HydrophobicContact CE1-CE3 4.28Å; F165-W218 HydrophobicContact CE2-CB 4.08Å; F165-W218 HydrophobicContact CE2-CE3 4.13Å; F165-W218 AromaticContact CG-CE3 3.83Å; F165-W218 HydrophobicContact CG-CE3 3.83Å; F165-W218 HydrophobicContact CG-CZ3 4.09Å; F165-W218 HydrophobicContact CZ-CB 4.36Å; F165-W218 HydrophobicContact CZ-CE3 4.31Å; I168-W218 HydrophobicContact CB-CZ3 4.48Å; I168-W218 HydrophobicContact CG2-CH2 3.83Å; I168-W218 HydrophobicContact CG2-CZ3 4.12Å; K169-W218 HydrophobicContact CD-CH2 4.32Å; K169-W218 HydrophobicContact CD-CZ3 4.48Å; K169-W218 HydrophobicContact CG-CH2 3.47Å; K169-W218 VanDerWaalsContact CG-CH2 3.47Å; K169-W218 HydrophobicContact CG-CZ2 4.33Å; K169-W218 HydrophobicContact CG-CZ3 3.86Å; L205-W218 HydrophobicContact CD1-CD2 3.75Å; L205-W218 HydrophobicContact CD1-CE3 3.83Å; L205-W218 HydrophobicContact CD1-CG 4.42Å; L205-W218 HydrophobicContact CD1-CH2 3.92Å; L205-W218 HydrophobicContact CD1-CZ2 3.84Å; L205-W218 HydrophobicContact CD1-CZ3 3.92Å; L205-W218 HydrophobicContact CD2-CH2 4.24Å; L205-W218 HydrophobicContact CD2-CZ2 3.75Å; L205-W218 HydrophobicContact CG-CZ2 4.47Å; L209-W218 HydrophobicContact CD2-CB 3.77Å; L209-W218 HydrophobicContact CD2-CG 3.96Å; Y214-W218 VanDerWaalsContact O-CB 3.23Å; Y214-W218 WeakPolarHBondContact O-CB 3.32Å; Y214-W218 PolarHBondContact O-N 2.99Å; R215-W218 PolarHBondContact O-N 3.25Å; F216-W218 VanDerWaalsContact C-N 3.25Å; F216-W218 PolarHBondContact O-N 2.9Å; W218-A221 PolarHBondContact O-N 3.31Å; W218-G223 WeakPolarHBondContact CZ2-O 3.25Å; W218-G223 PolarHBondContact NE1-O 3.15Å; W218-G223 VanDerWaalsContact O-CA 3.29Å; W218-G223 WeakPolarHBondContact O-CA 3.35Å; W218-G223 PolarHBondContact O-N 2.91Å; W218-C226 HydrophobicContact CZ2-CB 4.36Å; W218-I227 HydrophobicContact CZ2-CG1 4.32Å
219	V	94.3	Very high	94.5	Very high	17 Å²	17	36.8 Å²	36.8	10%	0.103	19%	0.189	C	C	.	.	H	α-helix	trans	-67.5	-43.9	177	173.4	0	0	0	0	111	R215 F216 A221 D222 V224 L250 M256 H259	R215-V219 WeakPolarHBondContact O-CG2 3.32Å; R215-V219 PolarHBondContact O-N 3.27Å; R215-V219 VanDerWaalsContact O-N 3.12Å; F216-V219 PolarHBondContact O-N 3.47Å; F216-V219 VanDerWaalsContact O-N 3.11Å; V219-A221 PolarHBondContact O-N 3.12Å; V219-D222 PolarHBondContact O-N 3.04Å; V219-D222 VanDerWaalsContact O-N 3.15Å; V219-V224 HydrophobicContact CG2-CG2 3.91Å; V219-L250 HydrophobicContact CG2-CD1 4.45Å; V219-L250 HydrophobicContact CG2-CD2 4.38Å; V219-M256 HydrophobicContact CG2-CE 3.55Å; V219-H259 HydrophobicContact CG1-CB 4.29Å
220	E	93.6	Very high	94.3	Very high	162 Å²	162	36.9 Å²	36.9	76%	0.757	19%	0.19	S	C	*	.	H	α-helix	trans	-61	-34.3	176.3	-72.3	177.7	175.2	0	0	112.3	F216 D222	F216-E220 WeakPolarHBondContact O-CG 3.4Å; F216-E220 PolarHBondContact O-N 3.23Å; E220-D222 PolarHBondContact O-N 2.94Å
221	A	93.4	Very high	94.1	Very high	23 Å²	23	33.4 Å²	33.4	19%	0.19	18%	0.177	C	C	.	.	T	Hydrogen-bonded Turn	trans	-81.8	18.5	177.3	0	0	0	0	0	114.4	K169 A217 W218 V219 G223	K169-A221 PolarHBondContact NZ-O 3.16Å; A217-A221 VanDerWaalsContact O-CB 3.23Å; A217-A221 WeakPolarHBondContact O-CB 3.47Å; A217-A221 PolarHBondContact O-N 3.47Å; W218-A221 PolarHBondContact O-N 3.31Å; V219-A221 PolarHBondContact O-N 3.12Å; A221-G223 PolarHBondContact O-N 3.09Å
222	D	92.4	Very high	93.8	Very high	77 Å²	77	36 Å²	36	41%	0.412	20%	0.196	S	C	.	.	T	Hydrogen-bonded Turn	trans	55.5	32	-176.3	-165.4	36.5	0	0	0	113.8	V219 E220 V224 N225	V219-D222 PolarHBondContact O-N 3.04Å; V219-D222 VanDerWaalsContact O-N 3.15Å; E220-D222 PolarHBondContact O-N 2.94Å; D222-V224 VanDerWaalsContact C-N 3.29Å; D222-V224 PolarHBondContact O-N 3.41Å; D222-N225 VanDerWaalsContact CG-ND2 3.3Å; D222-N225 PolarHBondContact OD1-ND2 2.93Å; D222-N225 PolarHBondContact OD2-ND2 3.43Å; D222-N225 VanDerWaalsContact OD2-ND2 3.1Å
223	G	94.6	Very high	93.2	Very high	0 Å²	0	34.9 Å²	34.9	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-70	-22.8	-176.1	0	0	0	0	0	114.1	W218 A221 C226 I227	W218-G223 WeakPolarHBondContact CZ2-O 3.25Å; W218-G223 PolarHBondContact NE1-O 3.15Å; W218-G223 VanDerWaalsContact O-CA 3.29Å; W218-G223 WeakPolarHBondContact O-CA 3.35Å; W218-G223 PolarHBondContact O-N 2.91Å; A221-G223 PolarHBondContact O-N 3.09Å; G223-C226 WeakPolarHBondContact O-CB 3.42Å; G223-C226 PolarHBondContact O-N 3.44Å; G223-I227 PolarHBondContact O-N 3.44Å
224	V	95.3	Very high	92.3	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-66.1	-42.4	179.3	-175	0	0	0	0	110.8	V219 D222 C226 I227 M228 L250 L260 Y263 I265	V219-V224 HydrophobicContact CG2-CG2 3.91Å; D222-V224 VanDerWaalsContact C-N 3.29Å; D222-V224 PolarHBondContact O-N 3.41Å; V224-C226 PolarHBondContact O-N 2.98Å; V224-I227 PolarHBondContact O-N 3.41Å; V224-I227 VanDerWaalsContact O-N 3.08Å; V224-M228 HydrophobicContact CG1-CG 4.3Å; V224-M228 WeakPolarHBondContact O-CG 3.34Å; V224-M228 PolarHBondContact O-N 3.06Å; V224-L250 HydrophobicContact CG2-CD1 4.12Å; V224-L260 HydrophobicContact CG1-CD2 3.89Å; V224-L260 HydrophobicContact CG2-CD2 3.77Å; V224-Y263 HydrophobicContact CB-CD1 3.9Å; V224-Y263 HydrophobicContact CB-CD2 4.12Å; V224-Y263 HydrophobicContact CB-CE1 3.78Å; V224-Y263 HydrophobicContact CB-CE2 4Å; V224-Y263 HydrophobicContact CB-CG 4.06Å; V224-Y263 HydrophobicContact CG1-CD1 3.68Å; V224-Y263 HydrophobicContact CG1-CD2 3.67Å; V224-Y263 HydrophobicContact CG1-CE1 4.09Å; V224-Y263 HydrophobicContact CG1-CE2 4.07Å; V224-Y263 HydrophobicContact CG1-CG 3.44Å; V224-Y263 VanDerWaalsContact CG1-CG 3.44Å; V224-Y263 HydrophobicContact CG2-CE2 4.25Å; V224-I265 HydrophobicContact CG1-CD1 4.34Å
225	N	93.2	Very high	91.6	Very high	79 Å²	79	40.2 Å²	40.2	42%	0.422	22%	0.215	S	C	.	.	H	α-helix	trans	-58.9	-34.6	174	-86.4	-32.2	0	0	0	112.5	D222 G229 Y263	D222-N225 VanDerWaalsContact CG-ND2 3.3Å; D222-N225 PolarHBondContact OD1-ND2 2.93Å; D222-N225 PolarHBondContact OD2-ND2 3.43Å; D222-N225 VanDerWaalsContact OD2-ND2 3.1Å; N225-G229 PolarHBondContact O-N 3.02Å; N225-Y263 HydrophobicContact CB-CE1 4.42Å; N225-Y263 VanDerWaalsContact OD1-CD1 3.3Å; N225-Y263 WeakPolarHBondContact OD1-CD1 3.02Å; N225-Y263 WeakPolarHBondContact OD1-CE1 3.23Å
226	C	94.1	Very high	91.2	Very high	12 Å²	12	41.6 Å²	41.6	8%	0.081	23%	0.234	C	C	.	.	H	α-helix	trans	-64.2	-45.6	174.3	-174	0	0	0	0	111.5	K169 W218 G223 V224 G229 V230	K169-C226 HydrophobicContact CG-CB 4.09Å; W218-C226 HydrophobicContact CZ2-CB 4.36Å; G223-C226 WeakPolarHBondContact O-CB 3.42Å; G223-C226 PolarHBondContact O-N 3.44Å; V224-C226 PolarHBondContact O-N 2.98Å; C226-G229 PolarHBondContact O-N 2.69Å; C226-V230 WeakPolarHBondContact O-CG2 3.47Å; C226-V230 PolarHBondContact O-N 3.15Å; C226-V230 VanDerWaalsContact O-N 3.16Å
227	I	95.2	Very high	90.9	Very high	0 Å²	0	43.4 Å²	43.4	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-62.9	-48.2	177.8	-62.8	170.5	0	0	0	110.2	L205 W218 G223 V224 G229 V230 L231 M243 I247 L250	L205-I227 HydrophobicContact CD2-CD1 4.22Å; L205-I227 HydrophobicContact CD2-CG1 4.14Å; W218-I227 HydrophobicContact CZ2-CG1 4.32Å; G223-I227 PolarHBondContact O-N 3.44Å; V224-I227 PolarHBondContact O-N 3.41Å; V224-I227 VanDerWaalsContact O-N 3.08Å; I227-G229 VanDerWaalsContact C-N 3.32Å; I227-G229 PolarHBondContact O-N 3Å; I227-V230 PolarHBondContact O-N 3.15Å; I227-V230 VanDerWaalsContact O-N 3.12Å; I227-L231 HydrophobicContact CG2-CD1 4.16Å; I227-L231 PolarHBondContact O-N 3.25Å; I227-M243 HydrophobicContact CB-SD 4.48Å; I227-M243 HydrophobicContact CG1-SD 4.38Å; I227-M243 HydrophobicContact CG2-CB 3.91Å; I227-M243 HydrophobicContact CG2-CG 4.41Å; I227-M243 HydrophobicContact CG2-SD 4.07Å; I227-I247 HydrophobicContact CG2-CD1 3.95Å; I227-I247 HydrophobicContact CG2-CG1 3.87Å; I227-L250 HydrophobicContact CD1-CD1 4.31Å
228	M	93.9	Very high	90.6	Very high	13 Å²	13	44.7 Å²	44.7	6%	0.064	25%	0.245	C	C	.	.	H	α-helix	trans	-61.6	-41.4	179.3	-65	-48.8	-64.1	0	0	111.5	V224 V230 L231 S232 I247 I265 V268	V224-M228 HydrophobicContact CG1-CG 4.3Å; V224-M228 WeakPolarHBondContact O-CG 3.34Å; V224-M228 PolarHBondContact O-N 3.06Å; M228-V230 VanDerWaalsContact C-N 3.27Å; M228-V230 PolarHBondContact O-N 3.28Å; M228-L231 PolarHBondContact O-N 2.91Å; M228-L231 VanDerWaalsContact O-N 3.15Å; M228-L231 HydrophobicContact SD-CD1 4.26Å; M228-S232 PolarHBondContact O-N 3.2Å; M228-S232 PolarHBondContact O-OG 3.46Å; M228-S232 VanDerWaalsContact O-OG 3.06Å; M228-I247 HydrophobicContact SD-CD1 3.88Å; M228-I265 HydrophobicContact CE-CG1 4.31Å; M228-I265 HydrophobicContact SD-CB 4.45Å; M228-I265 HydrophobicContact SD-CG1 3.81Å; M228-V268 HydrophobicContact CE-CB 3.63Å; M228-V268 HydrophobicContact CE-CG1 3.94Å; M228-V268 HydrophobicContact CE-CG2 3.54Å
229	G	90.9	Very high	90.3	Very high	13 Å²	13	45 Å²	45	13%	0.134	25%	0.247	C	C	.	.	H	α-helix	trans	-61	-32.2	175.4	0	0	0	0	0	113.9	N225 C226 I227 N233	N225-G229 PolarHBondContact O-N 3.02Å; C226-G229 PolarHBondContact O-N 2.69Å; I227-G229 VanDerWaalsContact C-N 3.32Å; I227-G229 PolarHBondContact O-N 3Å; G229-N233 PolarHBondContact O-ND2 2.88Å; G229-N233 VanDerWaalsContact O-ND2 3.09Å
230	V	90.9	Very high	90.2	Very high	2 Å²	2	45.6 Å²	45.6	1%	0.012	25%	0.248	C	C	.	.	H	α-helix	trans	-73.8	-42.1	173.4	175.5	0	0	0	0	111.1	L172 C226 I227 M228 N233 L239 M243	L172-V230 HydrophobicContact CB-CG2 3.97Å; C226-V230 WeakPolarHBondContact O-CG2 3.47Å; C226-V230 PolarHBondContact O-N 3.15Å; C226-V230 VanDerWaalsContact O-N 3.16Å; I227-V230 PolarHBondContact O-N 3.15Å; I227-V230 VanDerWaalsContact O-N 3.12Å; M228-V230 VanDerWaalsContact C-N 3.27Å; M228-V230 PolarHBondContact O-N 3.28Å; V230-N233 PolarHBondContact O-N 3.46Å; V230-L239 HydrophobicContact CG1-CD1 4.39Å; V230-L239 HydrophobicContact CG1-CD2 3.65Å; V230-L239 HydrophobicContact CG1-CG 3.89Å; V230-M243 HydrophobicContact CB-CG 4.18Å; V230-M243 HydrophobicContact CB-SD 4.17Å; V230-M243 HydrophobicContact CG1-CG 3.76Å; V230-M243 HydrophobicContact CG1-SD 4.12Å; V230-M243 HydrophobicContact CG2-SD 4.48Å
231	L	91.5	Very high	90.3	Very high	8 Å²	8	40.4 Å²	40.4	4%	0.042	22%	0.222	C	C	.	.	H	α-helix	trans	-66.5	-35.9	179.6	-73	175.4	0	0	0	113	I227 M228 N233 M243 I244 I247 V268 L269 I272	I227-L231 HydrophobicContact CG2-CD1 4.16Å; I227-L231 PolarHBondContact O-N 3.25Å; M228-L231 PolarHBondContact O-N 2.91Å; M228-L231 VanDerWaalsContact O-N 3.15Å; M228-L231 HydrophobicContact SD-CD1 4.26Å; L231-N233 PolarHBondContact O-N 3.44Å; L231-M243 HydrophobicContact CD1-CB 4.2Å; L231-M243 HydrophobicContact CD2-CB 3.55Å; L231-M243 HydrophobicContact CD2-CG 4.3Å; L231-M243 HydrophobicContact CG-CB 3.76Å; L231-M243 HydrophobicContact CG-CG 4.41Å; L231-I244 HydrophobicContact CD1-CG1 4.28Å; L231-I244 HydrophobicContact CD2-CG1 4.05Å; L231-I247 HydrophobicContact CD1-CD1 3.62Å; L231-V268 HydrophobicContact CB-CG1 3.91Å; L231-L269 HydrophobicContact CD1-CD2 4.16Å; L231-I272 HydrophobicContact CB-CD1 4.38Å; L231-I272 HydrophobicContact CD2-CD1 3.92Å
232	S	86.9	Confident	90.3	Very high	81 Å²	81	40 Å²	40	57%	0.566	22%	0.216	S	C	*	.	H	α-helix	trans	-68.7	-23.5	175.8	-59.1	0	0	0	0	113.1	M228	M228-S232 PolarHBondContact O-N 3.2Å; M228-S232 PolarHBondContact O-OG 3.46Å; M228-S232 VanDerWaalsContact O-OG 3.06Å
233	N	82.1	Confident	90.5	Very high	46 Å²	46	36.3 Å²	36.3	25%	0.246	20%	0.197	C	C	.	.	S	Bend	trans	-81.2	119.8	169.6	-64.2	-31.2	0	0	0	107.6	G229 V230 L231 C235	G229-N233 PolarHBondContact O-ND2 2.88Å; G229-N233 VanDerWaalsContact O-ND2 3.09Å; V230-N233 PolarHBondContact O-N 3.46Å; L231-N233 PolarHBondContact O-N 3.44Å; N233-C235 VanDerWaalsContact C-N 3.33Å; N233-C235 WeakPolarHBondContact O-CB 3.47Å; N233-C235 PolarHBondContact O-N 3.39Å
234	K	75.6	Confident	90.6	Very high	196 Å²	196	36.3 Å²	36.3	85%	0.852	20%	0.197	S	C	*	.			trans	-52.1	93.2	177.8	-66.8	-171.5	176.3	-168.4	0	111
235	C	83.1	Confident	90.7	Very high	19 Å²	19	37 Å²	37	13%	0.128	20%	0.199	C	C	.	.			trans	-110.6	161.3	-173.9	60.6	0	0	0	0	111	N233 L239 Q240	N233-C235 VanDerWaalsContact C-N 3.33Å; N233-C235 WeakPolarHBondContact O-CB 3.47Å; N233-C235 PolarHBondContact O-N 3.39Å; C235-L239 HydrophobicContact CB-CB 4.32Å; C235-L239 HydrophobicContact CB-CD2 3.92Å; C235-L239 HydrophobicContact CB-CG 4.4Å; C235-Q240 VanDerWaalsContact SG-CG 3.54Å
236	G	86.4	Confident	91	Very high	48 Å²	48	33.2 Å²	33.2	50%	0.495	18%	0.179	S	C	.	.			trans	-62.7	150.6	-179.4	0	0	0	0	0	112.5	Q238 L239 Q240	G236-Q238 PolarHBondContact O-N 3.44Å; G236-L239 PolarHBondContact O-N 3.01Å; G236-Q240 PolarHBondContact O-N 3.25Å; G236-Q240 VanDerWaalsContact O-N 3.07Å
237	F	89.1	Confident	91.1	Very high	95 Å²	95	32.6 Å²	32.6	42%	0.417	18%	0.175	S	C	.	.	H	α-helix	trans	-52.9	-29.7	-176.2	68.2	-94	0	0	0	114.5	Y241 K278 V281	F237-Y241 WeakPolarHBondContact O-CB 3.34Å; F237-Y241 PolarHBondContact O-N 2.9Å; F237-K278 HydrophobicContact CB-CG 3.98Å; F237-K278 HydrophobicContact CD1-CG 4.5Å; F237-K278 HydrophobicContact CD2-CG 4.25Å; F237-K278 HydrophobicContact CG-CG 3.99Å; F237-V281 HydrophobicContact CB-CG2 4.14Å; F237-V281 WeakPolarHBondContact O-CG2 3.3Å
238	Q	88.8	Confident	91.3	Very high	47 Å²	47	34.7 Å²	34.7	22%	0.22	18%	0.183	C	C	.	.	H	α-helix	trans	-66.3	-45.2	175.2	-179.5	62.5	32.5	0	0	111.4	Q199 G236 Y241 Q242	Q199-Q238 HydrophobicContact CG-CG 4.16Å; G236-Q238 PolarHBondContact O-N 3.44Å; Q238-Y241 WeakPolarHBondContact O-CB 3.32Å; Q238-Y241 PolarHBondContact O-N 3.46Å; Q238-Q242 VanDerWaalsContact O-CG 3.32Å; Q238-Q242 WeakPolarHBondContact O-CG 3.5Å; Q238-Q242 PolarHBondContact O-N 3.01Å
239	L	90.3	Very high	91.4	Very high	8 Å²	8	34 Å²	34	4%	0.042	18%	0.18	C	C	.	.	H	α-helix	trans	-70.6	-40.1	179.7	-173.2	56.9	0	0	0	110.8	V198 A202 V230 C235 G236 Y241 Q242 M243	V198-L239 HydrophobicContact CG1-CD1 4.03Å; V198-L239 HydrophobicContact CG1-CD2 3.79Å; A202-L239 HydrophobicContact CB-CD1 3.72Å; V230-L239 HydrophobicContact CG1-CD1 4.39Å; V230-L239 HydrophobicContact CG1-CD2 3.65Å; V230-L239 HydrophobicContact CG1-CG 3.89Å; C235-L239 HydrophobicContact CB-CB 4.32Å; C235-L239 HydrophobicContact CB-CD2 3.92Å; C235-L239 HydrophobicContact CB-CG 4.4Å; G236-L239 PolarHBondContact O-N 3.01Å; L239-Y241 VanDerWaalsContact C-N 3.35Å; L239-Y241 PolarHBondContact O-N 3.24Å; L239-Q242 PolarHBondContact O-N 3.41Å; L239-M243 HydrophobicContact CD1-CE 4.12Å; L239-M243 HydrophobicContact CD1-CG 4.21Å; L239-M243 HydrophobicContact CG-CG 4.34Å; L239-M243 WeakPolarHBondContact O-CB 3.36Å; L239-M243 WeakPolarHBondContact O-CG 3.49Å; L239-M243 PolarHBondContact O-N 2.95Å
240	Q	92.9	Very high	91.6	Very high	28 Å²	28	33.4 Å²	33.4	13%	0.131	17%	0.174	C	C	.	.	H	α-helix	trans	-53	-53.1	170.4	-69.1	179.1	-31.2	0	0	110.7	C235 G236 Q242 M243 I244	C235-Q240 VanDerWaalsContact SG-CG 3.54Å; G236-Q240 PolarHBondContact O-N 3.25Å; G236-Q240 VanDerWaalsContact O-N 3.07Å; Q240-Q242 VanDerWaalsContact C-N 3.35Å; Q240-Q242 PolarHBondContact O-N 3.23Å; Q240-M243 PolarHBondContact O-N 3.46Å; Q240-I244 HydrophobicContact CB-CD1 4.42Å; Q240-I244 WeakPolarHBondContact O-CB 3.46Å; Q240-I244 WeakPolarHBondContact O-CD1 3.47Å; Q240-I244 WeakPolarHBondContact O-CG1 3.45Å; Q240-I244 PolarHBondContact O-N 3.42Å
241	Y	94.9	Very high	91.8	Very high	53 Å²	53	33.3 Å²	33.3	21%	0.208	17%	0.173	C	C	.	.	H	α-helix	trans	-54.1	-48.2	176.5	171.3	-95.5	0	0	0	112.3	F237 Q238 L239 M243 I244 F245 K280 I284	F237-Y241 WeakPolarHBondContact O-CB 3.34Å; F237-Y241 PolarHBondContact O-N 2.9Å; Q238-Y241 WeakPolarHBondContact O-CB 3.32Å; Q238-Y241 PolarHBondContact O-N 3.46Å; L239-Y241 VanDerWaalsContact C-N 3.35Å; L239-Y241 PolarHBondContact O-N 3.24Å; Y241-M243 PolarHBondContact O-N 3.42Å; Y241-I244 PolarHBondContact O-N 3.34Å; Y241-F245 HydrophobicContact CE1-CD2 4.28Å; Y241-F245 AromaticContact CZ-CD2 3.87Å; Y241-F245 WeakPolarHBondContact O-CB 3.37Å; Y241-F245 PolarHBondContact O-N 3.05Å; Y241-K280 HydrophobicContact CD2-CB 4.39Å; Y241-K280 HydrophobicContact CD2-CG 4.14Å; Y241-K280 WeakPolarHBondContact CD2-O 3.47Å; Y241-I284 HydrophobicContact CD2-CB 4.03Å; Y241-I284 HydrophobicContact CD2-CG2 3.64Å; Y241-I284 HydrophobicContact CE2-CB 3.96Å; Y241-I284 HydrophobicContact CE2-CG1 4.35Å; Y241-I284 HydrophobicContact CE2-CG2 4.11Å
242	Q	94.6	Very high	91.8	Very high	15 Å²	15	35.4 Å²	35.4	7%	0.07	18%	0.182	C	C	.	.	H	α-helix	trans	-68.3	-36.9	-176.8	-66.5	179.3	-68	0	0	113.4	Q199 A202 Q206 Q238 L239 Q240 S246	Q199-Q242 PolarHBondContact O-NE2 2.95Å; Q199-Q242 PolarHBondContact O-OE1 3.31Å; A202-Q242 HydrophobicContact CB-CB 3.82Å; A202-Q242 HydrophobicContact CB-CG 4.41Å; Q206-Q242 HydrophobicContact CG-CB 4.45Å; Q206-Q242 VanDerWaalsContact OE1-CG 3.3Å; Q238-Q242 VanDerWaalsContact O-CG 3.32Å; Q238-Q242 WeakPolarHBondContact O-CG 3.5Å; Q238-Q242 PolarHBondContact O-N 3.01Å; L239-Q242 PolarHBondContact O-N 3.41Å; Q240-Q242 VanDerWaalsContact C-N 3.35Å; Q240-Q242 PolarHBondContact O-N 3.23Å; Q242-S246 PolarHBondContact O-N 2.96Å; Q242-S246 PolarHBondContact O-OG 2.93Å
243	M	96.1	Very high	92	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-68.7	-44.7	175.3	-71	-55.2	94.1	0	0	111.2	L172 A202 I227 V230 L231 L239 Q240 Y241 F245 S246 I247	L172-M243 HydrophobicContact CD2-CE 4.34Å; A202-M243 HydrophobicContact CB-CE 3.36Å; I227-M243 HydrophobicContact CB-SD 4.48Å; I227-M243 HydrophobicContact CG1-SD 4.38Å; I227-M243 HydrophobicContact CG2-CB 3.91Å; I227-M243 HydrophobicContact CG2-CG 4.41Å; I227-M243 HydrophobicContact CG2-SD 4.07Å; V230-M243 HydrophobicContact CB-CG 4.18Å; V230-M243 HydrophobicContact CB-SD 4.17Å; V230-M243 HydrophobicContact CG1-CG 3.76Å; V230-M243 HydrophobicContact CG1-SD 4.12Å; V230-M243 HydrophobicContact CG2-SD 4.48Å; L231-M243 HydrophobicContact CD1-CB 4.2Å; L231-M243 HydrophobicContact CD2-CB 3.55Å; L231-M243 HydrophobicContact CD2-CG 4.3Å; L231-M243 HydrophobicContact CG-CB 3.76Å; L231-M243 HydrophobicContact CG-CG 4.41Å; L239-M243 HydrophobicContact CD1-CE 4.12Å; L239-M243 HydrophobicContact CD1-CG 4.21Å; L239-M243 HydrophobicContact CG-CG 4.34Å; L239-M243 WeakPolarHBondContact O-CB 3.36Å; L239-M243 WeakPolarHBondContact O-CG 3.49Å; L239-M243 PolarHBondContact O-N 2.95Å; Q240-M243 PolarHBondContact O-N 3.46Å; Y241-M243 PolarHBondContact O-N 3.42Å; M243-F245 VanDerWaalsContact C-N 3.33Å; M243-F245 PolarHBondContact O-N 2.75Å; M243-S246 VanDerWaalsContact O-CB 3.29Å; M243-S246 WeakPolarHBondContact O-CB 3.42Å; M243-S246 PolarHBondContact O-N 3.07Å; M243-S246 VanDerWaalsContact O-N 3.12Å; M243-I247 PolarHBondContact O-N 2.97Å
244	I	97.5	Very high	92.2	Very high	0 Å²	0	32.2 Å²	32.2	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-66.5	-37.5	176.8	-60.3	163.6	0	0	0	110.7	L231 Q240 Y241 S246 I247 W248 L269 I272 V281 I284 I285 A288	L231-I244 HydrophobicContact CD1-CG1 4.28Å; L231-I244 HydrophobicContact CD2-CG1 4.05Å; Q240-I244 HydrophobicContact CB-CD1 4.42Å; Q240-I244 WeakPolarHBondContact O-CB 3.46Å; Q240-I244 WeakPolarHBondContact O-CD1 3.47Å; Q240-I244 WeakPolarHBondContact O-CG1 3.45Å; Q240-I244 PolarHBondContact O-N 3.42Å; Y241-I244 PolarHBondContact O-N 3.34Å; I244-S246 VanDerWaalsContact C-N 3.26Å; I244-S246 PolarHBondContact O-N 3.07Å; I244-I247 CarbonylContact O-C 3.59Å; I244-I247 WeakPolarHBondContact O-CB 3.33Å; I244-I247 PolarHBondContact O-N 2.98Å; I244-I247 VanDerWaalsContact O-N 3.12Å; I244-W248 WeakPolarHBondContact O-CB 3.45Å; I244-W248 PolarHBondContact O-N 3.16Å; I244-L269 HydrophobicContact CD1-CD2 4.16Å; I244-L269 HydrophobicContact CG1-CD2 3.7Å; I244-L269 HydrophobicContact CG2-CD1 4.13Å; I244-L269 HydrophobicContact CG2-CD2 4.31Å; I244-I272 HydrophobicContact CD1-CD1 4.31Å; I244-I272 HydrophobicContact CD1-CG2 4.21Å; I244-V281 HydrophobicContact CD1-CG1 4.18Å; I244-I284 HydrophobicContact CB-CG2 3.97Å; I244-I284 HydrophobicContact CG2-CB 4.42Å; I244-I284 HydrophobicContact CG2-CG1 4.09Å; I244-I284 HydrophobicContact CG2-CG2 3.78Å; I244-I285 HydrophobicContact CD1-CD1 3.85Å; I244-I285 HydrophobicContact CD1-CG1 3.63Å; I244-I285 HydrophobicContact CG2-CG1 3.97Å; I244-A288 HydrophobicContact CG2-CB 4.48Å
245	F	97.6	Very high	92.9	Very high	13 Å²	13	28.6 Å²	28.6	6%	0.057	15%	0.148	C	C	.	.	H	α-helix	trans	-60.1	-39.5	172.3	-169.6	-73.7	0	0	0	111.5	Q206 Y241 M243 I247 W248 L249 I284	Q206-F245 HydrophobicContact CB-CD1 4.39Å; Q206-F245 HydrophobicContact CG-CD1 4.02Å; Q206-F245 VanDerWaalsContact NE2-CB 3.26Å; Y241-F245 HydrophobicContact CE1-CD2 4.28Å; Y241-F245 AromaticContact CZ-CD2 3.87Å; Y241-F245 WeakPolarHBondContact O-CB 3.37Å; Y241-F245 PolarHBondContact O-N 3.05Å; M243-F245 VanDerWaalsContact C-N 3.33Å; M243-F245 PolarHBondContact O-N 2.75Å; F245-I247 VanDerWaalsContact C-N 3.34Å; F245-W248 HydrophobicContact CD1-CE3 4.37Å; F245-W248 HydrophobicContact CD2-CE3 4.45Å; F245-W248 HydrophobicContact CE1-CE3 4.16Å; F245-W248 HydrophobicContact CE1-CZ3 4.1Å; F245-W248 HydrophobicContact CE2-CE3 4.25Å; F245-W248 HydrophobicContact CE2-CZ3 4.07Å; F245-W248 HydrophobicContact CZ-CE3 4.09Å; F245-W248 AromaticContact CZ-CZ3 3.72Å; F245-W248 HydrophobicContact CZ-CZ3 3.72Å; F245-W248 WeakPolarHBondContact O-CB 3.47Å; F245-W248 PolarHBondContact O-N 3.31Å; F245-L249 HydrophobicContact CD1-CD1 3.77Å; F245-L249 HydrophobicContact CD1-CG 3.82Å; F245-L249 HydrophobicContact CE1-CD1 3.62Å; F245-L249 HydrophobicContact CE1-CD2 3.88Å; F245-L249 HydrophobicContact CE1-CG 3.64Å; F245-L249 WeakPolarHBondContact O-CG 3.43Å; F245-L249 PolarHBondContact O-N 3.38Å; F245-I284 HydrophobicContact CB-CD1 4.27Å; F245-I284 HydrophobicContact CB-CG1 4.08Å; F245-I284 HydrophobicContact CD2-CD1 3.76Å; F245-I284 HydrophobicContact CD2-CG1 4.32Å; F245-I284 HydrophobicContact CE2-CD1 4.48Å; F245-I284 HydrophobicContact CG-CD1 4.28Å
246	S	97.8	Very high	93.1	Very high	0 Å²	0	27.8 Å²	27.8	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-61.3	-44.8	174.6	-58.2	0	0	0	0	110.3	Q242 M243 I244 W248 L249 L250	Q242-S246 PolarHBondContact O-N 2.96Å; Q242-S246 PolarHBondContact O-OG 2.93Å; M243-S246 VanDerWaalsContact O-CB 3.29Å; M243-S246 WeakPolarHBondContact O-CB 3.42Å; M243-S246 PolarHBondContact O-N 3.07Å; M243-S246 VanDerWaalsContact O-N 3.12Å; I244-S246 VanDerWaalsContact C-N 3.26Å; I244-S246 PolarHBondContact O-N 3.07Å; S246-W248 PolarHBondContact O-N 3.2Å; S246-L249 WeakPolarHBondContact O-CB 3.4Å; S246-L249 PolarHBondContact O-N 3.13Å; S246-L250 WeakPolarHBondContact O-CG 3.45Å; S246-L250 PolarHBondContact O-N 3.26Å; S246-L250 VanDerWaalsContact O-N 3.13Å
247	I	97.7	Very high	93.3	Very high	0 Å²	0	25.5 Å²	25.5	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-59.8	-45.7	173.8	-65	172.9	0	0	0	111.6	I227 M228 L231 M243 I244 F245 L249 L250 A251 I265 L269 F292	I227-I247 HydrophobicContact CG2-CD1 3.95Å; I227-I247 HydrophobicContact CG2-CG1 3.87Å; M228-I247 HydrophobicContact SD-CD1 3.88Å; L231-I247 HydrophobicContact CD1-CD1 3.62Å; M243-I247 PolarHBondContact O-N 2.97Å; I244-I247 CarbonylContact O-C 3.59Å; I244-I247 WeakPolarHBondContact O-CB 3.33Å; I244-I247 PolarHBondContact O-N 2.98Å; I244-I247 VanDerWaalsContact O-N 3.12Å; F245-I247 VanDerWaalsContact C-N 3.34Å; I247-L249 VanDerWaalsContact C-N 3.3Å; I247-L249 PolarHBondContact O-N 3.17Å; I247-L250 WeakPolarHBondContact O-CB 3.4Å; I247-L250 PolarHBondContact O-N 3.38Å; I247-A251 PolarHBondContact O-N 3.13Å; I247-I265 HydrophobicContact CD1-CG2 4.06Å; I247-I265 HydrophobicContact CG2-CD1 4.38Å; I247-I265 HydrophobicContact CG2-CG2 3.86Å; I247-L269 HydrophobicContact CD1-CD2 4.38Å; I247-F292 HydrophobicContact CG2-CE2 4.09Å; I247-F292 HydrophobicContact CG2-CZ 3.7Å
248	W	97.7	Very high	93.3	Very high	43 Å²	43	23.6 Å²	23.6	16%	0.163	11%	0.112	C	C	.	.	H	α-helix	trans	-58.1	-41.5	177.7	173.4	79	0	0	0	112	I244 F245 S246 L250 A251 F252 I284 A288 N291	I244-W248 WeakPolarHBondContact O-CB 3.45Å; I244-W248 PolarHBondContact O-N 3.16Å; F245-W248 HydrophobicContact CD1-CE3 4.37Å; F245-W248 HydrophobicContact CD2-CE3 4.45Å; F245-W248 HydrophobicContact CE1-CE3 4.16Å; F245-W248 HydrophobicContact CE1-CZ3 4.1Å; F245-W248 HydrophobicContact CE2-CE3 4.25Å; F245-W248 HydrophobicContact CE2-CZ3 4.07Å; F245-W248 HydrophobicContact CZ-CE3 4.09Å; F245-W248 AromaticContact CZ-CZ3 3.72Å; F245-W248 HydrophobicContact CZ-CZ3 3.72Å; F245-W248 WeakPolarHBondContact O-CB 3.47Å; F245-W248 PolarHBondContact O-N 3.31Å; S246-W248 PolarHBondContact O-N 3.2Å; W248-L250 VanDerWaalsContact C-N 3.35Å; W248-L250 PolarHBondContact O-N 2.88Å; W248-A251 PolarHBondContact O-N 3.12Å; W248-F252 AromaticContact CD2-CE2 3.62Å; W248-F252 HydrophobicContact CD2-CE2 3.62Å; W248-F252 HydrophobicContact CD2-CZ 4.36Å; W248-F252 AromaticContact CE2-CE2 3.33Å; W248-F252 AromaticContact CE2-CZ 3.6Å; W248-F252 AromaticContact CE3-CE2 3.82Å; W248-F252 HydrophobicContact CE3-CE2 3.82Å; W248-F252 HydrophobicContact CG-CE2 4.37Å; W248-F252 AromaticContact CH2-CE2 3.55Å; W248-F252 HydrophobicContact CH2-CE2 3.55Å; W248-F252 AromaticContact CH2-CZ 3.71Å; W248-F252 HydrophobicContact CH2-CZ 3.71Å; W248-F252 AromaticContact CZ2-CE2 3.34Å; W248-F252 HydrophobicContact CZ2-CE2 3.34Å; W248-F252 AromaticContact CZ2-CZ 3.27Å; W248-F252 HydrophobicContact CZ2-CZ 3.27Å; W248-F252 AromaticContact CZ3-CE2 3.78Å; W248-F252 HydrophobicContact CZ3-CE2 3.78Å; W248-F252 HydrophobicContact CZ3-CZ 4.41Å; W248-F252 AromaticContact NE1-CE2 3.88Å; W248-F252 WeakPolarHBondContact O-CD2 3.35Å; W248-I284 HydrophobicContact CB-CD1 3.92Å; W248-I284 HydrophobicContact CB-CG1 4.43Å; W248-I284 HydrophobicContact CD2-CD1 3.95Å; W248-I284 HydrophobicContact CE3-CD1 4.25Å; W248-I284 HydrophobicContact CG-CD1 3.83Å; W248-A288 HydrophobicContact CB-CB 4.25Å; W248-N291 PolarHBondContact NE1-ND2 3.06Å; W248-N291 VanDerWaalsContact NE1-ND2 3.15Å; W248-N291 PolarHBondContact O-ND2 3.43Å
249	L	96.4	Very high	93.3	Very high	0 Å²	0	25.7 Å²	25.7	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-61.3	-40.9	173.2	-72.5	175.8	0	0	0	112.3	Q206 L209 F245 S246 I247 A251	Q206-L249 WeakPolarHBondContact O-CD1 3.4Å; L209-L249 HydrophobicContact CB-CB 4.27Å; L209-L249 HydrophobicContact CB-CD1 3.61Å; F245-L249 HydrophobicContact CD1-CD1 3.77Å; F245-L249 HydrophobicContact CD1-CG 3.82Å; F245-L249 HydrophobicContact CE1-CD1 3.62Å; F245-L249 HydrophobicContact CE1-CD2 3.88Å; F245-L249 HydrophobicContact CE1-CG 3.64Å; F245-L249 WeakPolarHBondContact O-CG 3.43Å; F245-L249 PolarHBondContact O-N 3.38Å; S246-L249 WeakPolarHBondContact O-CB 3.4Å; S246-L249 PolarHBondContact O-N 3.13Å; I247-L249 VanDerWaalsContact C-N 3.3Å; I247-L249 PolarHBondContact O-N 3.17Å; L249-A251 VanDerWaalsContact C-N 3.34Å
250	L	96.1	Very high	93.4	Very high	0 Å²	0	25.3 Å²	25.3	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-67.2	-36.7	177.2	-57.1	176.4	0	0	0	111.3	L209 R215 V219 V224 I227 S246 I247 W248 F252 S253 M256 L260	L209-L250 HydrophobicContact CD1-CD2 4.06Å; L209-L250 HydrophobicContact CD1-CG 4.48Å; L209-L250 HydrophobicContact CD2-CD2 3.84Å; L209-L250 HydrophobicContact CG-CD2 4.48Å; R215-L250 HydrophobicContact CB-CD2 3.97Å; R215-L250 HydrophobicContact CG-CD2 4.24Å; V219-L250 HydrophobicContact CG2-CD1 4.45Å; V219-L250 HydrophobicContact CG2-CD2 4.38Å; V224-L250 HydrophobicContact CG2-CD1 4.12Å; I227-L250 HydrophobicContact CD1-CD1 4.31Å; S246-L250 WeakPolarHBondContact O-CG 3.45Å; S246-L250 PolarHBondContact O-N 3.26Å; S246-L250 VanDerWaalsContact O-N 3.13Å; I247-L250 WeakPolarHBondContact O-CB 3.4Å; I247-L250 PolarHBondContact O-N 3.38Å; W248-L250 VanDerWaalsContact C-N 3.35Å; W248-L250 PolarHBondContact O-N 2.88Å; L250-F252 PolarHBondContact O-N 3.05Å; L250-F252 VanDerWaalsContact O-N 3.16Å; L250-S253 PolarHBondContact O-N 3.13Å; L250-M256 HydrophobicContact CB-CE 3.59Å; L250-M256 HydrophobicContact CD2-CE 3.35Å; L250-M256 HydrophobicContact CG-CE 3.96Å; L250-M256 WeakPolarHBondContact O-CB 3.5Å; L250-L260 HydrophobicContact CB-CD1 3.89Å; L250-L260 HydrophobicContact CB-CD2 4.45Å; L250-L260 HydrophobicContact CD1-CD2 4.12Å
251	A	95.2	Very high	93	Very high	0 Å²	0	27.3 Å²	27.3	0%	0	13%	0.125	C	C	.	.	T	Hydrogen-bonded Turn	trans	-71.9	-1.9	-177.7	0	0	0	0	0	114.8	I247 W248 L249 S253 C257 L260 N291 F292	I247-A251 PolarHBondContact O-N 3.13Å; W248-A251 PolarHBondContact O-N 3.12Å; L249-A251 VanDerWaalsContact C-N 3.34Å; A251-S253 VanDerWaalsContact C-N 3.33Å; A251-C257 PolarHBondContact O-SG 3.29Å; A251-L260 HydrophobicContact CB-CD1 4.49Å; A251-N291 HydrophobicContact CB-CB 3.86Å; A251-F292 HydrophobicContact CB-CD1 4.1Å; A251-F292 HydrophobicContact CB-CE1 3.85Å; A251-F292 HydrophobicContact CB-CZ 4.14Å
252	F	91.9	Very high	92.6	Very high	51 Å²	51	34.3 Å²	34.3	22%	0.224	15%	0.152	C	C	.	.	T	Hydrogen-bonded Turn	trans	-74	-22.7	173.4	-87.8	-80.2	0	0	0	114.1	W248 L250 N291	W248-F252 AromaticContact CD2-CE2 3.62Å; W248-F252 HydrophobicContact CD2-CE2 3.62Å; W248-F252 HydrophobicContact CD2-CZ 4.36Å; W248-F252 AromaticContact CE2-CE2 3.33Å; W248-F252 AromaticContact CE2-CZ 3.6Å; W248-F252 AromaticContact CE3-CE2 3.82Å; W248-F252 HydrophobicContact CE3-CE2 3.82Å; W248-F252 HydrophobicContact CG-CE2 4.37Å; W248-F252 AromaticContact CH2-CE2 3.55Å; W248-F252 HydrophobicContact CH2-CE2 3.55Å; W248-F252 AromaticContact CH2-CZ 3.71Å; W248-F252 HydrophobicContact CH2-CZ 3.71Å; W248-F252 AromaticContact CZ2-CE2 3.34Å; W248-F252 HydrophobicContact CZ2-CE2 3.34Å; W248-F252 AromaticContact CZ2-CZ 3.27Å; W248-F252 HydrophobicContact CZ2-CZ 3.27Å; W248-F252 AromaticContact CZ3-CE2 3.78Å; W248-F252 HydrophobicContact CZ3-CE2 3.78Å; W248-F252 HydrophobicContact CZ3-CZ 4.41Å; W248-F252 AromaticContact NE1-CE2 3.88Å; W248-F252 WeakPolarHBondContact O-CD2 3.35Å; L250-F252 PolarHBondContact O-N 3.05Å; L250-F252 VanDerWaalsContact O-N 3.16Å; F252-N291 WeakPolarHBondContact CE2-ND2 3.44Å
253	S	89.2	Confident	92.4	Very high	13 Å²	13	35.8 Å²	35.8	9%	0.091	16%	0.157	C	C	.	.	S	Bend	trans	-97.6	123.7	-177.4	176	0	0	0	0	110.3	L250 A251 Q255 M256 C257	L250-S253 PolarHBondContact O-N 3.13Å; A251-S253 VanDerWaalsContact C-N 3.33Å; S253-Q255 VanDerWaalsContact C-N 3.33Å; S253-Q255 PolarHBondContact O-N 3.48Å; S253-M256 VanDerWaalsContact CB-SD 3.5Å; S253-M256 WeakPolarHBondContact O-CB 3.21Å; S253-M256 PolarHBondContact O-N 3.37Å; S253-C257 PolarHBondContact O-N 3.29Å
254	P	88.1	Confident	92	Very high	47 Å²	47	39.6 Å²	39.6	31%	0.305	18%	0.177	S	C	.	.	H	α-helix	trans	-57	-43.6	179.8	-25.4	32.9	0	0	0	113.6	M256 C257 E258 K295 T297	P254-M256 PolarHBondContact O-N 3.19Å; P254-C257 WeakPolarHBondContact O-CB 3.29Å; P254-C257 PolarHBondContact O-N 3.28Å; P254-C257 VanDerWaalsContact O-N 3.16Å; P254-E258 PolarHBondContact O-N 3.16Å; P254-K295 WeakPolarHBondContact CB-O 3.02Å; P254-K295 WeakPolarHBondContact CG-O 3.43Å; P254-T297 HydrophobicContact CB-CG2 3.65Å; P254-T297 HydrophobicContact CG-CG2 3.97Å
255	Q	88.6	Confident	91.9	Very high	121 Å²	121	39.8 Å²	39.8	57%	0.565	18%	0.178	S	C	*	.	H	α-helix	trans	-59.7	-38.5	177.1	-68.3	175	-15.3	0	0	111.3	F216 S253 E258 H259	F216-Q255 HydrophobicContact CE1-CB 4.32Å; S253-Q255 VanDerWaalsContact C-N 3.33Å; S253-Q255 PolarHBondContact O-N 3.48Å; Q255-E258 PolarHBondContact O-N 3.47Å; Q255-H259 PolarHBondContact O-CD2 2.88Å; Q255-H259 VanDerWaalsContact O-CD2 3.23Å; Q255-H259 PolarHBondContact O-N 3.27Å
256	M	89.3	Confident	91.7	Very high	1 Å²	1	39.4 Å²	39.4	1%	0.005	18%	0.177	C	C	.	.	H	α-helix	trans	-71.5	-37.4	178.7	-64.8	177.3	71.4	0	0	111.9	R215 F216 V219 L250 S253 P254 E258 H259 L260	R215-M256 HydrophobicContact CB-CE 3.52Å; R215-M256 HydrophobicContact CB-SD 3.66Å; F216-M256 HydrophobicContact CD1-CG 4.46Å; F216-M256 HydrophobicContact CE1-CG 4.09Å; F216-M256 HydrophobicContact CE2-SD 4.44Å; F216-M256 HydrophobicContact CZ-CG 4.24Å; V219-M256 HydrophobicContact CG2-CE 3.55Å; L250-M256 HydrophobicContact CB-CE 3.59Å; L250-M256 HydrophobicContact CD2-CE 3.35Å; L250-M256 HydrophobicContact CG-CE 3.96Å; L250-M256 WeakPolarHBondContact O-CB 3.5Å; S253-M256 VanDerWaalsContact CB-SD 3.5Å; S253-M256 WeakPolarHBondContact O-CB 3.21Å; S253-M256 PolarHBondContact O-N 3.37Å; P254-M256 PolarHBondContact O-N 3.19Å; M256-E258 PolarHBondContact O-N 3.48Å; M256-H259 PolarHBondContact O-N 2.97Å; M256-L260 WeakPolarHBondContact O-CB 3.23Å; M256-L260 VanDerWaalsContact O-CG 3.23Å; M256-L260 WeakPolarHBondContact O-CG 3.42Å; M256-L260 PolarHBondContact O-N 3.43Å
257	C	90.4	Very high	91.5	Very high	0 Å²	0	39.8 Å²	39.8	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-55.1	-36.4	173.8	-71.9	0	0	0	0	111.8	A251 S253 P254 L260 Y305	A251-C257 PolarHBondContact O-SG 3.29Å; S253-C257 PolarHBondContact O-N 3.29Å; P254-C257 WeakPolarHBondContact O-CB 3.29Å; P254-C257 PolarHBondContact O-N 3.28Å; P254-C257 VanDerWaalsContact O-N 3.16Å; C257-L260 PolarHBondContact O-N 3.12Å; C257-Y305 HydrophobicContact CB-CE2 4.37Å; C257-Y305 PolarHBondContact O-OH 2.97Å
258	E	88.3	Confident	91.3	Very high	56 Å²	56	41 Å²	41	26%	0.262	19%	0.186	S	C	.	.	H	α-helix	trans	-65.3	-42	175.7	-68.5	168.7	-161.4	0	0	112.4	P254 Q255 M256 R261 E298 T301	P254-E258 PolarHBondContact O-N 3.16Å; Q255-E258 PolarHBondContact O-N 3.47Å; M256-E258 PolarHBondContact O-N 3.48Å; E258-R261 PolarHBondContact O-NE 2.76Å; E258-E298 WeakPolarHBondContact OE1-CG 3.4Å; E258-T301 HydrophobicContact CG-CG2 4.46Å
259	H	89.6	Confident	91.2	Very high	90 Å²	90	38.9 Å²	38.9	42%	0.417	18%	0.178	S	C	.	.	H	α-helix	trans	-69	-39.1	176.6	-74.3	-75.8	0	0	0	112.8	V219 Q255 M256 R261 R262 Y263	V219-H259 HydrophobicContact CG1-CB 4.29Å; Q255-H259 PolarHBondContact O-CD2 2.88Å; Q255-H259 VanDerWaalsContact O-CD2 3.23Å; Q255-H259 PolarHBondContact O-N 3.27Å; M256-H259 PolarHBondContact O-N 2.97Å; H259-R261 PolarHBondContact O-N 2.86Å; H259-R262 PolarHBondContact O-N 3.13Å; H259-Y263 WeakPolarHBondContact O-CE2 3.41Å
260	L	91.5	Very high	91.2	Very high	1 Å²	1	38.9 Å²	38.9	1%	0.005	18%	0.178	C	C	.	.	H	α-helix	trans	-64.4	-22.4	-176.5	-73.7	173.6	0	0	0	113.3	V224 L250 A251 M256 C257 R262 Y263 I265 F292	V224-L260 HydrophobicContact CG1-CD2 3.89Å; V224-L260 HydrophobicContact CG2-CD2 3.77Å; L250-L260 HydrophobicContact CB-CD1 3.89Å; L250-L260 HydrophobicContact CB-CD2 4.45Å; L250-L260 HydrophobicContact CD1-CD2 4.12Å; A251-L260 HydrophobicContact CB-CD1 4.49Å; M256-L260 WeakPolarHBondContact O-CB 3.23Å; M256-L260 VanDerWaalsContact O-CG 3.23Å; M256-L260 WeakPolarHBondContact O-CG 3.42Å; M256-L260 PolarHBondContact O-N 3.43Å; C257-L260 PolarHBondContact O-N 3.12Å; L260-R262 PolarHBondContact O-N 3.11Å; L260-Y263 PolarHBondContact O-N 3.47Å; L260-I265 HydrophobicContact CB-CD1 3.84Å; L260-I265 HydrophobicContact CD2-CD1 3.74Å; L260-I265 HydrophobicContact CG-CD1 4.26Å; L260-F292 HydrophobicContact CB-CE1 4.17Å; L260-F292 HydrophobicContact CD1-CE1 3.83Å; L260-F292 HydrophobicContact CD1-CZ 4.38Å
261	R	85.2	Confident	91	Very high	69 Å²	69	41.8 Å²	41.8	26%	0.26	19%	0.194	S	C	.	.	G	3₁₀ helix	trans	-53.7	-29	177.7	-73.6	-170.5	-78.1	179.7	-12.2	114.2	E258 H259 Y263 E298 T301 E304 Y305	E258-R261 PolarHBondContact O-NE 2.76Å; H259-R261 PolarHBondContact O-N 2.86Å; R261-Y263 VanDerWaalsContact C-N 3.27Å; R261-Y263 PolarHBondContact O-N 3.38Å; R261-E298 IonicContact NH2-OE2 3.86Å; R261-E298 PolarHBondContact NH2-OE2 2.91Å; R261-T301 HydrophobicContact CG-CG2 4.08Å; R261-T301 PolarHBondContact NE-OG1 3.48Å; R261-T301 PolarHBondContact NH1-OG1 2.81Å; R261-T301 PolarHBondContact NH2-OG1 3.44Å; R261-E304 WeakPolarHBondContact CD-OE2 3.4Å; R261-E304 IonicContact CZ-OE2 3.93Å; R261-E304 IonicContact NE-OE2 3.55Å; R261-E304 IonicContact NH1-OE2 3.73Å; R261-E304 PolarHBondContact NH1-OE2 3.17Å; R261-Y305 HydrophobicContact CG-CE1 4.13Å; R261-Y305 HydrophobicContact CG-CE2 3.81Å; R261-Y305 WeakPolarHBondContact CG-OH 3.16Å; R261-Y305 PolarHBondContact N-OH 3.04Å; R261-Y305 VanDerWaalsContact N-OH 3.1Å
262	R	86.4	Confident	91	Very high	201 Å²	201	42.3 Å²	42.3	76%	0.758	20%	0.196	S	C	*	.	G	3₁₀ helix	trans	-77.5	-8.2	-172.8	-59.1	-179.6	-175	175.1	2.3	114.2	H259 L260	H259-R262 PolarHBondContact O-N 3.13Å; L260-R262 PolarHBondContact O-N 3.11Å
263	Y	89	Confident	91.2	Very high	46 Å²	46	40.3 Å²	40.3	18%	0.18	19%	0.188	C	C	.	.	G	3₁₀ helix	trans	-106.2	11.6	-166.4	-65	-86.8	0	0	0	114.7	V224 N225 H259 L260 R261 I265	V224-Y263 HydrophobicContact CB-CD1 3.9Å; V224-Y263 HydrophobicContact CB-CD2 4.12Å; V224-Y263 HydrophobicContact CB-CE1 3.78Å; V224-Y263 HydrophobicContact CB-CE2 4Å; V224-Y263 HydrophobicContact CB-CG 4.06Å; V224-Y263 HydrophobicContact CG1-CD1 3.68Å; V224-Y263 HydrophobicContact CG1-CD2 3.67Å; V224-Y263 HydrophobicContact CG1-CE1 4.09Å; V224-Y263 HydrophobicContact CG1-CE2 4.07Å; V224-Y263 HydrophobicContact CG1-CG 3.44Å; V224-Y263 VanDerWaalsContact CG1-CG 3.44Å; V224-Y263 HydrophobicContact CG2-CE2 4.25Å; N225-Y263 HydrophobicContact CB-CE1 4.42Å; N225-Y263 VanDerWaalsContact OD1-CD1 3.3Å; N225-Y263 WeakPolarHBondContact OD1-CD1 3.02Å; N225-Y263 WeakPolarHBondContact OD1-CE1 3.23Å; H259-Y263 WeakPolarHBondContact O-CE2 3.41Å; L260-Y263 PolarHBondContact O-N 3.47Å; R261-Y263 VanDerWaalsContact C-N 3.27Å; R261-Y263 PolarHBondContact O-N 3.38Å; Y263-I265 PolarHBondContact O-N 3.31Å; Y263-I265 VanDerWaalsContact O-N 3.13Å
264	N	88.8	Confident	91.3	Very high	80 Å²	80	46.4 Å²	46.4	43%	0.428	22%	0.215	S	C	.	.			trans	48.7	42.1	-179.4	-68.3	-26.4	0	0	0	113	P267	N264-P267 HydrophobicContact CB-CG 4.46Å; N264-P267 WeakPolarHBondContact O-CD 3.41Å
265	I	94.7	Very high	91.4	Very high	4 Å²	4	50.7 Å²	50.7	2%	0.021	23%	0.231	C	C	.	.	H	α-helix	trans	-66.2	-47.1	-176.7	-62.8	172.8	0	0	0	110.8	V224 M228 I247 L260 Y263 V268 L269 F292	V224-I265 HydrophobicContact CG1-CD1 4.34Å; M228-I265 HydrophobicContact CE-CG1 4.31Å; M228-I265 HydrophobicContact SD-CB 4.45Å; M228-I265 HydrophobicContact SD-CG1 3.81Å; I247-I265 HydrophobicContact CD1-CG2 4.06Å; I247-I265 HydrophobicContact CG2-CD1 4.38Å; I247-I265 HydrophobicContact CG2-CG2 3.86Å; L260-I265 HydrophobicContact CB-CD1 3.84Å; L260-I265 HydrophobicContact CD2-CD1 3.74Å; L260-I265 HydrophobicContact CG-CD1 4.26Å; Y263-I265 PolarHBondContact O-N 3.31Å; Y263-I265 VanDerWaalsContact O-N 3.13Å; I265-V268 PolarHBondContact O-N 2.97Å; I265-L269 HydrophobicContact CG2-CD1 3.96Å; I265-L269 HydrophobicContact CG2-CG 3.93Å; I265-L269 WeakPolarHBondContact O-CG 3.43Å; I265-L269 PolarHBondContact O-N 3.34Å; I265-F292 HydrophobicContact CD1-CZ 4.17Å; I265-F292 HydrophobicContact CG2-CE2 3.98Å; I265-F292 HydrophobicContact CG2-CZ 3.93Å
266	I	94.8	Very high	91.4	Very high	5 Å²	5	46.1 Å²	46.1	3%	0.026	21%	0.212	C	C	.	.	H	α-helix	trans	-56.2	-52.6	-175.8	-57.3	-56	0	0	0	111.7	V268 L269 S270 F289 F292 Y305 A308 M309	I266-V268 VanDerWaalsContact C-N 3.33Å; I266-V268 PolarHBondContact O-N 3.03Å; I266-L269 PolarHBondContact O-N 3.07Å; I266-L269 VanDerWaalsContact O-N 3.16Å; I266-S270 WeakPolarHBondContact O-CB 3.29Å; I266-S270 PolarHBondContact O-N 3.49Å; I266-S270 PolarHBondContact O-OG 3.03Å; I266-F289 HydrophobicContact CD1-CD1 3.75Å; I266-F289 HydrophobicContact CD1-CE1 3.71Å; I266-F289 HydrophobicContact CG2-CE1 4.22Å; I266-F292 HydrophobicContact CD1-CD2 3.68Å; I266-F292 HydrophobicContact CD1-CE2 4.04Å; I266-F292 HydrophobicContact CD1-CG 4.32Å; I266-Y305 HydrophobicContact CD1-CD1 3.96Å; I266-Y305 HydrophobicContact CD1-CE1 4.45Å; I266-Y305 HydrophobicContact CG1-CD1 3.71Å; I266-Y305 HydrophobicContact CG1-CE1 4.26Å; I266-A308 HydrophobicContact CB-CB 3.98Å; I266-A308 HydrophobicContact CG1-CB 4.24Å; I266-A308 HydrophobicContact CG2-CB 3.91Å; I266-M309 HydrophobicContact CD1-CE 3.65Å; I266-M309 HydrophobicContact CD1-CG 4.41Å; I266-M309 HydrophobicContact CG2-CB 4.27Å; I266-M309 HydrophobicContact CG2-CG 3.56Å
267	P	92.7	Very high	91.3	Very high	7 Å²	7	52.2 Å²	52.2	5%	0.045	25%	0.249	C	C	.	.	H	α-helix	trans	-52.9	-45.3	177.3	-26.2	31.8	0	0	0	114.7	N264 S270 D271 R363	N264-P267 HydrophobicContact CB-CG 4.46Å; N264-P267 WeakPolarHBondContact O-CD 3.41Å; P267-S270 PolarHBondContact O-N 3.4Å; P267-D271 VanDerWaalsContact O-CG 3.25Å; P267-D271 PolarHBondContact O-N 3.48Å; P267-D271 VanDerWaalsContact O-N 3.09Å; P267-R363 VanDerWaalsContact CB-CZ 3.4Å; P267-R363 PolarHBondContact O-NH2 3.47Å
268	V	93.7	Very high	91.4	Very high	25 Å²	25	56.8 Å²	56.8	15%	0.152	27%	0.269	C	S	.	.	H	α-helix	trans	-66.5	-41.4	-179.9	174.4	0	0	0	0	111.4	M228 L231 I265 I266 D271 I272	M228-V268 HydrophobicContact CE-CB 3.63Å; M228-V268 HydrophobicContact CE-CG1 3.94Å; M228-V268 HydrophobicContact CE-CG2 3.54Å; L231-V268 HydrophobicContact CB-CG1 3.91Å; I265-V268 PolarHBondContact O-N 2.97Å; I266-V268 VanDerWaalsContact C-N 3.33Å; I266-V268 PolarHBondContact O-N 3.03Å; V268-D271 PolarHBondContact O-N 2.99Å; V268-I272 HydrophobicContact CG1-CD1 4.01Å; V268-I272 VanDerWaalsContact O-CG1 3.3Å; V268-I272 WeakPolarHBondContact O-CG1 3.47Å; V268-I272 PolarHBondContact O-N 2.97Å; V268-I272 VanDerWaalsContact O-N 3.15Å
269	L	96.5	Very high	91.6	Very high	0 Å²	0	59.5 Å²	59.5	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-68.5	-36.1	177.8	-62.8	-158.4	0	0	0	112.1	L231 I244 I247 I265 I266 I272 L273 I285 A288 F289	L231-L269 HydrophobicContact CD1-CD2 4.16Å; I244-L269 HydrophobicContact CD1-CD2 4.16Å; I244-L269 HydrophobicContact CG1-CD2 3.7Å; I244-L269 HydrophobicContact CG2-CD1 4.13Å; I244-L269 HydrophobicContact CG2-CD2 4.31Å; I247-L269 HydrophobicContact CD1-CD2 4.38Å; I265-L269 HydrophobicContact CG2-CD1 3.96Å; I265-L269 HydrophobicContact CG2-CG 3.93Å; I265-L269 WeakPolarHBondContact O-CG 3.43Å; I265-L269 PolarHBondContact O-N 3.34Å; I266-L269 PolarHBondContact O-N 3.07Å; I266-L269 VanDerWaalsContact O-N 3.16Å; L269-I272 PolarHBondContact O-N 3.5Å; L269-L273 WeakPolarHBondContact O-CB 3.15Å; L269-L273 PolarHBondContact O-N 3.21Å; L269-I285 HydrophobicContact CB-CG2 4.14Å; L269-A288 HydrophobicContact CD1-CB 4.16Å; L269-F289 HydrophobicContact CB-CE1 3.64Å; L269-F289 HydrophobicContact CB-CZ 3.71Å; L269-F289 HydrophobicContact CD1-CE1 4.12Å; L269-F289 HydrophobicContact CG-CE1 4.41Å
270	S	94.7	Very high	91.9	Very high	0 Å²	0	58.6 Å²	58.6	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-64	-39.5	175.9	-62.8	0	0	0	0	112.4	I266 P267 L273 Q274 C312 V314	I266-S270 WeakPolarHBondContact O-CB 3.29Å; I266-S270 PolarHBondContact O-N 3.49Å; I266-S270 PolarHBondContact O-OG 3.03Å; P267-S270 PolarHBondContact O-N 3.4Å; S270-L273 PolarHBondContact O-N 2.78Å; S270-Q274 PolarHBondContact O-N 3.33Å; S270-Q274 VanDerWaalsContact O-N 3.09Å; S270-C312 VanDerWaalsContact OG-CB 3.32Å; S270-C312 WeakPolarHBondContact OG-CB 3.3Å; S270-V314 WeakPolarHBondContact OG-CG2 3.5Å
271	D	92.9	Very high	92.1	Very high	60 Å²	60	58.5 Å²	58.5	32%	0.321	28%	0.276	S	S	.	.	H	α-helix	trans	-65.8	-45.2	175.4	-62.7	-12.2	0	0	0	111	P267 V268 L273 Q274 E275 R363	P267-D271 VanDerWaalsContact O-CG 3.25Å; P267-D271 PolarHBondContact O-N 3.48Å; P267-D271 VanDerWaalsContact O-N 3.09Å; V268-D271 PolarHBondContact O-N 2.99Å; D271-L273 VanDerWaalsContact C-N 3.31Å; D271-L273 PolarHBondContact O-N 3.48Å; D271-Q274 WeakPolarHBondContact O-CB 3.33Å; D271-Q274 PolarHBondContact O-N 3.17Å; D271-E275 PolarHBondContact O-N 2.88Å; D271-E275 VanDerWaalsContact O-N 3.11Å; D271-R363 VanDerWaalsContact CG-NH2 3.32Å; D271-R363 IonicContact OD1-CZ 3.68Å; D271-R363 IonicContact OD1-NH1 2.69Å; D271-R363 PolarHBondContact OD1-NH1 2.97Å; D271-R363 IonicContact OD1-NH2 2.76Å; D271-R363 PolarHBondContact OD1-NH2 3.16Å; D271-R363 IonicContact OD2-CZ 2.72Å; D271-R363 IonicContact OD2-NH1 3.86Å; D271-R363 IonicContact OD2-NH2 2.78Å; D271-R363 PolarHBondContact OD2-NH2 3.33Å
272	I	94.9	Very high	92.5	Very high	11 Å²	11	55.5 Å²	55.5	6%	0.056	27%	0.266	C	S	.	.	H	α-helix	trans	-63.5	-39	177.8	-63.1	167.2	0	0	0	110.6	L231 I244 V268 L269 Q274 E275 S276 V281 I285	L231-I272 HydrophobicContact CB-CD1 4.38Å; L231-I272 HydrophobicContact CD2-CD1 3.92Å; I244-I272 HydrophobicContact CD1-CD1 4.31Å; I244-I272 HydrophobicContact CD1-CG2 4.21Å; V268-I272 HydrophobicContact CG1-CD1 4.01Å; V268-I272 VanDerWaalsContact O-CG1 3.3Å; V268-I272 WeakPolarHBondContact O-CG1 3.47Å; V268-I272 PolarHBondContact O-N 2.97Å; V268-I272 VanDerWaalsContact O-N 3.15Å; L269-I272 PolarHBondContact O-N 3.5Å; I272-Q274 VanDerWaalsContact C-N 3.3Å; I272-Q274 PolarHBondContact O-N 2.97Å; I272-E275 PolarHBondContact O-N 2.99Å; I272-S276 WeakPolarHBondContact O-CB 2.89Å; I272-S276 PolarHBondContact O-N 3.39Å; I272-V281 HydrophobicContact CG2-CG1 3.88Å; I272-I285 HydrophobicContact CB-CD1 4.12Å; I272-I285 HydrophobicContact CG2-CD1 3.82Å
273	L	95.4	Very high	93	Very high	9 Å²	9	50.4 Å²	50.4	5%	0.047	25%	0.246	C	C	.	.	H	α-helix	trans	-61.4	-40.1	176.4	-176.9	60.3	0	0	0	111.6	L269 S270 D271 T282 I285 L286 F289 L321	L269-L273 WeakPolarHBondContact O-CB 3.15Å; L269-L273 PolarHBondContact O-N 3.21Å; S270-L273 PolarHBondContact O-N 2.78Å; D271-L273 VanDerWaalsContact C-N 3.31Å; D271-L273 PolarHBondContact O-N 3.48Å; L273-T282 HydrophobicContact CD1-CG2 3.87Å; L273-I285 HydrophobicContact CB-CD1 4.05Å; L273-I285 HydrophobicContact CB-CG2 4.16Å; L273-I285 HydrophobicContact CD1-CB 4.5Å; L273-I285 HydrophobicContact CD1-CD1 4.48Å; L273-I285 HydrophobicContact CD1-CG2 4.36Å; L273-I285 HydrophobicContact CD2-CG2 4.2Å; L273-I285 HydrophobicContact CG-CG2 4.49Å; L273-L286 HydrophobicContact CD2-CD2 4.44Å; L273-F289 HydrophobicContact CD2-CE2 4.01Å; L273-L321 HydrophobicContact CD1-CD1 4.22Å
274	Q	92.1	Very high	93.4	Very high	141 Å²	141	48.8 Å²	48.8	66%	0.659	24%	0.24	S	C	*	.	H	α-helix	trans	-67.3	-38.3	178.7	-169	174.9	-13.9	0	0	112.9	S270 D271 I272	S270-Q274 PolarHBondContact O-N 3.33Å; S270-Q274 VanDerWaalsContact O-N 3.09Å; D271-Q274 WeakPolarHBondContact O-CB 3.33Å; D271-Q274 PolarHBondContact O-N 3.17Å; I272-Q274 VanDerWaalsContact C-N 3.3Å; I272-Q274 PolarHBondContact O-N 2.97Å
275	E	90.2	Very high	93.9	Very high	138 Å²	138	45 Å²	45	65%	0.645	22%	0.22	S	C	*	.	H	α-helix	trans	-86.9	-21.7	-177.5	-65.2	-175.4	171.8	0	0	113.3	D271 I272	D271-E275 PolarHBondContact O-N 2.88Å; D271-E275 VanDerWaalsContact O-N 3.11Å; I272-E275 PolarHBondContact O-N 2.99Å
276	S	87.8	Confident	94	Very high	24 Å²	24	44.8 Å²	44.8	17%	0.168	22%	0.219	C	C	.	.			trans	-77.4	129.5	-172.7	175.9	0	0	0	0	112.7	I272 K278 V281	I272-S276 WeakPolarHBondContact O-CB 2.89Å; I272-S276 PolarHBondContact O-N 3.39Å; S276-K278 PolarHBondContact OG-N 3.5Å; S276-K278 VanDerWaalsContact OG-N 3.15Å; S276-K278 PolarHBondContact OG-O 3.43Å; S276-V281 WeakPolarHBondContact OG-CB 3.27Å
277	V	87.7	Confident	94.2	Very high	129 Å²	129	45.2 Å²	45.2	78%	0.782	22%	0.224	S	C	*	.			trans	-103.1	5.8	168.7	-59.6	0	0	0	0	112.6
278	K	92.6	Very high	94.4	Very high	97 Å²	97	44.9 Å²	44.9	42%	0.422	22%	0.222	S	C	.	.			trans	-101.6	112.6	-175.1	-61.3	-59.2	-179.2	-170.8	0	109.9	F237 S276 K280 V281 T282	F237-K278 HydrophobicContact CB-CG 3.98Å; F237-K278 HydrophobicContact CD1-CG 4.5Å; F237-K278 HydrophobicContact CD2-CG 4.25Å; F237-K278 HydrophobicContact CG-CG 3.99Å; S276-K278 PolarHBondContact OG-N 3.5Å; S276-K278 VanDerWaalsContact OG-N 3.15Å; S276-K278 PolarHBondContact OG-O 3.43Å; K278-K280 PolarHBondContact O-N 3.05Å; K278-K280 VanDerWaalsContact O-N 3.12Å; K278-V281 HydrophobicContact CB-CB 4.38Å; K278-V281 HydrophobicContact CB-CG2 4.08Å; K278-V281 WeakPolarHBondContact O-CB 3.35Å; K278-V281 PolarHBondContact O-N 3.49Å; K278-T282 PolarHBondContact O-N 3Å; K278-T282 VanDerWaalsContact O-N 3.1Å; K278-T282 PolarHBondContact O-OG1 3.21Å
279	E	93	Very high	94.7	Very high	112 Å²	112	43.7 Å²	43.7	52%	0.523	21%	0.214	S	C	.	.	H	α-helix	trans	-50.6	-40.9	-178.9	-67.8	-177.1	177.4	0	0	113.3	V281 T282 R283 Y326 I331	E279-V281 VanDerWaalsContact C-N 3.28Å; E279-V281 PolarHBondContact O-N 3.21Å; E279-T282 CarbonylContact O-C 3.58Å; E279-T282 WeakPolarHBondContact O-CB 3.3Å; E279-T282 PolarHBondContact O-N 3.06Å; E279-R283 WeakPolarHBondContact O-CB 3.49Å; E279-R283 PolarHBondContact O-N 3.37Å; E279-Y326 HydrophobicContact CG-CD1 4.44Å; E279-Y326 HydrophobicContact CG-CE1 4.25Å; E279-I331 HydrophobicContact CB-CD1 4.48Å
280	K	94.6	Very high	94.7	Very high	71 Å²	71	46.8 Å²	46.8	31%	0.309	23%	0.226	S	C	.	.	H	α-helix	trans	-63.1	-32.6	178.8	80	-175.3	-153.7	-175.4	0	113.9	Y241 K278 I284	Y241-K280 HydrophobicContact CD2-CB 4.39Å; Y241-K280 HydrophobicContact CD2-CG 4.14Å; Y241-K280 WeakPolarHBondContact CD2-O 3.47Å; K278-K280 PolarHBondContact O-N 3.05Å; K278-K280 VanDerWaalsContact O-N 3.12Å; K280-I284 PolarHBondContact O-N 2.86Å
281	V	95.6	Very high	94.8	Very high	0 Å²	0	47.3 Å²	47.3	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-75.2	-43.5	177	176.5	0	0	0	0	108.6	F237 I244 I272 S276 K278 E279 I284 I285	F237-V281 HydrophobicContact CB-CG2 4.14Å; F237-V281 WeakPolarHBondContact O-CG2 3.3Å; I244-V281 HydrophobicContact CD1-CG1 4.18Å; I272-V281 HydrophobicContact CG2-CG1 3.88Å; S276-V281 WeakPolarHBondContact OG-CB 3.27Å; K278-V281 HydrophobicContact CB-CB 4.38Å; K278-V281 HydrophobicContact CB-CG2 4.08Å; K278-V281 WeakPolarHBondContact O-CB 3.35Å; K278-V281 PolarHBondContact O-N 3.49Å; E279-V281 VanDerWaalsContact C-N 3.28Å; E279-V281 PolarHBondContact O-N 3.21Å; V281-I284 VanDerWaalsContact O-CG2 3.28Å; V281-I284 WeakPolarHBondContact O-CG2 3.34Å; V281-I284 PolarHBondContact O-N 3.23Å; V281-I285 HydrophobicContact CG1-CD1 3.83Å; V281-I285 VanDerWaalsContact O-CG1 3.3Å; V281-I285 WeakPolarHBondContact O-CG1 3.46Å; V281-I285 PolarHBondContact O-N 3.31Å; V281-I285 VanDerWaalsContact O-N 3.07Å
282	T	95.6	Very high	95	Very high	6 Å²	6	44.4 Å²	44.4	4%	0.037	21%	0.213	C	C	.	.	H	α-helix	trans	-54.8	-53.2	172.3	-57	0	0	0	0	111.1	L273 K278 E279 I284 I285 L286 L321	L273-T282 HydrophobicContact CD1-CG2 3.87Å; K278-T282 PolarHBondContact O-N 3Å; K278-T282 VanDerWaalsContact O-N 3.1Å; K278-T282 PolarHBondContact O-OG1 3.21Å; E279-T282 CarbonylContact O-C 3.58Å; E279-T282 WeakPolarHBondContact O-CB 3.3Å; E279-T282 PolarHBondContact O-N 3.06Å; T282-I284 PolarHBondContact O-N 3.38Å; T282-I285 PolarHBondContact O-N 3.35Å; T282-I285 VanDerWaalsContact O-N 3.16Å; T282-L286 HydrophobicContact CG2-CD1 3.88Å; T282-L286 HydrophobicContact CG2-CG 4.35Å; T282-L286 VanDerWaalsContact O-CG 3.3Å; T282-L286 WeakPolarHBondContact O-CG 3.39Å; T282-L286 PolarHBondContact O-N 3.41Å; T282-L321 HydrophobicContact CG2-CD1 4.32Å; T282-L321 HydrophobicContact CG2-CD2 4.43Å
283	R	96.4	Very high	94.9	Very high	94 Å²	94	44.2 Å²	44.2	36%	0.355	21%	0.213	S	C	.	.	H	α-helix	trans	-51.5	-50.8	177.8	-175.8	-171.8	169.1	125.1	-3.9	112.3	E279 I285 L286 A287 D328 D330 I331	E279-R283 WeakPolarHBondContact O-CB 3.49Å; E279-R283 PolarHBondContact O-N 3.37Å; R283-I285 VanDerWaalsContact C-N 3.35Å; R283-I285 PolarHBondContact O-N 2.9Å; R283-L286 PolarHBondContact O-N 3.34Å; R283-A287 WeakPolarHBondContact O-CB 3.33Å; R283-A287 PolarHBondContact O-N 3.23Å; R283-D328 WeakPolarHBondContact CD-OD2 3.39Å; R283-D328 IonicContact CZ-OD1 3.65Å; R283-D328 IonicContact CZ-OD2 2.75Å; R283-D328 IonicContact NE-OD2 3.8Å; R283-D328 IonicContact NH1-OD1 3.69Å; R283-D328 PolarHBondContact NH1-OD1 2.78Å; R283-D328 IonicContact NH1-OD2 2.78Å; R283-D328 PolarHBondContact NH1-OD2 2.83Å; R283-D330 IonicContact CZ-OD2 2.65Å; R283-D330 IonicContact NH1-OD2 3.45Å; R283-D330 PolarHBondContact NH1-OD2 3.05Å; R283-D330 IonicContact NH2-OD2 3.3Å; R283-D330 PolarHBondContact NH2-OD2 3.47Å; R283-I331 HydrophobicContact CB-CD1 4Å; R283-I331 HydrophobicContact CB-CG1 3.86Å; R283-I331 HydrophobicContact CG-CG1 4.01Å
284	I	97.8	Very high	94.9	Very high	11 Å²	11	47.7 Å²	47.7	6%	0.056	23%	0.228	C	C	.	.	H	α-helix	trans	-71.5	-29.9	-176.2	-163.9	60.8	0	0	0	112.7	Y241 I244 F245 W248 K280 V281 T282 A288	Y241-I284 HydrophobicContact CD2-CB 4.03Å; Y241-I284 HydrophobicContact CD2-CG2 3.64Å; Y241-I284 HydrophobicContact CE2-CB 3.96Å; Y241-I284 HydrophobicContact CE2-CG1 4.35Å; Y241-I284 HydrophobicContact CE2-CG2 4.11Å; I244-I284 HydrophobicContact CB-CG2 3.97Å; I244-I284 HydrophobicContact CG2-CB 4.42Å; I244-I284 HydrophobicContact CG2-CG1 4.09Å; I244-I284 HydrophobicContact CG2-CG2 3.78Å; F245-I284 HydrophobicContact CB-CD1 4.27Å; F245-I284 HydrophobicContact CB-CG1 4.08Å; F245-I284 HydrophobicContact CD2-CD1 3.76Å; F245-I284 HydrophobicContact CD2-CG1 4.32Å; F245-I284 HydrophobicContact CE2-CD1 4.48Å; F245-I284 HydrophobicContact CG-CD1 4.28Å; W248-I284 HydrophobicContact CB-CD1 3.92Å; W248-I284 HydrophobicContact CB-CG1 4.43Å; W248-I284 HydrophobicContact CD2-CD1 3.95Å; W248-I284 HydrophobicContact CE3-CD1 4.25Å; W248-I284 HydrophobicContact CG-CD1 3.83Å; K280-I284 PolarHBondContact O-N 2.86Å; V281-I284 VanDerWaalsContact O-CG2 3.28Å; V281-I284 WeakPolarHBondContact O-CG2 3.34Å; V281-I284 PolarHBondContact O-N 3.23Å; T282-I284 PolarHBondContact O-N 3.38Å; I284-A288 WeakPolarHBondContact O-CB 3.43Å; I284-A288 PolarHBondContact O-N 3.23Å
285	I	98.1	Very high	95	Very high	0 Å²	0	43.7 Å²	43.7	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-68.4	-47.1	173.9	-68.1	168	0	0	0	110.5	I244 L269 I272 L273 V281 T282 R283 A287 A288 F289	I244-I285 HydrophobicContact CD1-CD1 3.85Å; I244-I285 HydrophobicContact CD1-CG1 3.63Å; I244-I285 HydrophobicContact CG2-CG1 3.97Å; L269-I285 HydrophobicContact CB-CG2 4.14Å; I272-I285 HydrophobicContact CB-CD1 4.12Å; I272-I285 HydrophobicContact CG2-CD1 3.82Å; L273-I285 HydrophobicContact CB-CD1 4.05Å; L273-I285 HydrophobicContact CB-CG2 4.16Å; L273-I285 HydrophobicContact CD1-CB 4.5Å; L273-I285 HydrophobicContact CD1-CD1 4.48Å; L273-I285 HydrophobicContact CD1-CG2 4.36Å; L273-I285 HydrophobicContact CD2-CG2 4.2Å; L273-I285 HydrophobicContact CG-CG2 4.49Å; V281-I285 HydrophobicContact CG1-CD1 3.83Å; V281-I285 VanDerWaalsContact O-CG1 3.3Å; V281-I285 WeakPolarHBondContact O-CG1 3.46Å; V281-I285 PolarHBondContact O-N 3.31Å; V281-I285 VanDerWaalsContact O-N 3.07Å; T282-I285 PolarHBondContact O-N 3.35Å; T282-I285 VanDerWaalsContact O-N 3.16Å; R283-I285 VanDerWaalsContact C-N 3.35Å; R283-I285 PolarHBondContact O-N 2.9Å; I285-A287 VanDerWaalsContact C-N 3.34Å; I285-A287 PolarHBondContact O-N 3.37Å; I285-A288 WeakPolarHBondContact O-CB 3.35Å; I285-A288 PolarHBondContact O-N 3.05Å; I285-A288 VanDerWaalsContact O-N 3.13Å; I285-F289 HydrophobicContact CG2-CD2 3.9Å; I285-F289 HydrophobicContact CG2-CE1 4.27Å; I285-F289 HydrophobicContact CG2-CE2 3.5Å; I285-F289 VanDerWaalsContact CG2-CE2 3.5Å; I285-F289 HydrophobicContact CG2-CG 4.45Å; I285-F289 HydrophobicContact CG2-CZ 3.71Å; I285-F289 WeakPolarHBondContact O-CG 3.19Å; I285-F289 PolarHBondContact O-N 3.44Å
286	L	97.9	Very high	95	Very high	0 Å²	0	37.1 Å²	37.1	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-60	-45.7	178.2	-64.8	174.3	0	0	0	111.2	L273 T282 R283 A288 F289 R290 L318 I331 D334 I335 L338	L273-L286 HydrophobicContact CD2-CD2 4.44Å; T282-L286 HydrophobicContact CG2-CD1 3.88Å; T282-L286 HydrophobicContact CG2-CG 4.35Å; T282-L286 VanDerWaalsContact O-CG 3.3Å; T282-L286 WeakPolarHBondContact O-CG 3.39Å; T282-L286 PolarHBondContact O-N 3.41Å; R283-L286 PolarHBondContact O-N 3.34Å; L286-A288 VanDerWaalsContact C-N 3.3Å; L286-A288 PolarHBondContact O-N 3.49Å; L286-F289 PolarHBondContact O-N 3.16Å; L286-R290 PolarHBondContact O-N 3.18Å; L286-L318 HydrophobicContact CD2-CD2 3.46Å; L286-L318 VanDerWaalsContact CD2-CD2 3.46Å; L286-I331 HydrophobicContact CD1-CG2 3.91Å; L286-D334 HydrophobicContact CB-CB 3.94Å; L286-I335 HydrophobicContact CD1-CD1 4.31Å; L286-I335 HydrophobicContact CD1-CG1 3.83Å; L286-I335 HydrophobicContact CD2-CG1 4.49Å; L286-L338 HydrophobicContact CB-CD1 4.33Å; L286-L338 HydrophobicContact CD2-CD1 3.79Å
287	A	97.9	Very high	95	Very high	15 Å²	15	40.4 Å²	40.4	12%	0.124	20%	0.197	C	C	.	.	H	α-helix	trans	-62.1	-36.2	175.5	0	0	0	0	0	112.5	R283 I285 N291 D334	R283-A287 WeakPolarHBondContact O-CB 3.33Å; R283-A287 PolarHBondContact O-N 3.23Å; I285-A287 VanDerWaalsContact C-N 3.34Å; I285-A287 PolarHBondContact O-N 3.37Å; A287-N291 WeakPolarHBondContact O-CB 3.23Å; A287-N291 PolarHBondContact O-N 3.27Å; A287-D334 WeakPolarHBondContact CA-OD2 3.38Å; A287-D334 PolarHBondContact N-OD2 3.1Å
288	A	97.9	Very high	95	Very high	0 Å²	0	38 Å²	38	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-66.9	-45.8	174.8	0	0	0	0	0	111.8	I244 W248 L269 I284 I285 L286 R290 N291 F292	I244-A288 HydrophobicContact CG2-CB 4.48Å; W248-A288 HydrophobicContact CB-CB 4.25Å; L269-A288 HydrophobicContact CD1-CB 4.16Å; I284-A288 WeakPolarHBondContact O-CB 3.43Å; I284-A288 PolarHBondContact O-N 3.23Å; I285-A288 WeakPolarHBondContact O-CB 3.35Å; I285-A288 PolarHBondContact O-N 3.05Å; I285-A288 VanDerWaalsContact O-N 3.13Å; L286-A288 VanDerWaalsContact C-N 3.3Å; L286-A288 PolarHBondContact O-N 3.49Å; A288-R290 VanDerWaalsContact C-N 3.35Å; A288-R290 PolarHBondContact O-N 2.85Å; A288-N291 PolarHBondContact O-N 3Å; A288-F292 HydrophobicContact CB-CE2 4.44Å; A288-F292 WeakPolarHBondContact O-CD2 3.41Å; A288-F292 PolarHBondContact O-N 3.38Å
289	F	98.1	Very high	94.6	Very high	0 Å²	0	41.4 Å²	41.4	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-59.7	-44.4	174.6	-69.9	-19.3	0	0	0	112	I266 L269 L273 I285 L286 N291 F292 L293 M309 V314 L338	I266-F289 HydrophobicContact CD1-CD1 3.75Å; I266-F289 HydrophobicContact CD1-CE1 3.71Å; I266-F289 HydrophobicContact CG2-CE1 4.22Å; L269-F289 HydrophobicContact CB-CE1 3.64Å; L269-F289 HydrophobicContact CB-CZ 3.71Å; L269-F289 HydrophobicContact CD1-CE1 4.12Å; L269-F289 HydrophobicContact CG-CE1 4.41Å; L273-F289 HydrophobicContact CD2-CE2 4.01Å; I285-F289 HydrophobicContact CG2-CD2 3.9Å; I285-F289 HydrophobicContact CG2-CE1 4.27Å; I285-F289 HydrophobicContact CG2-CE2 3.5Å; I285-F289 VanDerWaalsContact CG2-CE2 3.5Å; I285-F289 HydrophobicContact CG2-CG 4.45Å; I285-F289 HydrophobicContact CG2-CZ 3.71Å; I285-F289 WeakPolarHBondContact O-CG 3.19Å; I285-F289 PolarHBondContact O-N 3.44Å; L286-F289 PolarHBondContact O-N 3.16Å; F289-N291 VanDerWaalsContact C-N 3.34Å; F289-N291 PolarHBondContact O-N 3.17Å; F289-F292 PolarHBondContact O-N 2.94Å; F289-L293 PolarHBondContact O-N 2.82Å; F289-L293 VanDerWaalsContact O-N 3.16Å; F289-M309 HydrophobicContact CB-CE 3.61Å; F289-M309 HydrophobicContact CB-SD 3.97Å; F289-M309 HydrophobicContact CD1-CE 3.65Å; F289-M309 HydrophobicContact CD1-SD 4.33Å; F289-M309 HydrophobicContact CE1-CE 4.49Å; F289-M309 HydrophobicContact CG-CE 3.79Å; F289-M309 HydrophobicContact CG-SD 4.06Å; F289-V314 HydrophobicContact CD2-CG1 4.17Å; F289-V314 HydrophobicContact CE2-CG1 3.98Å; F289-V314 HydrophobicContact CE2-CG2 4.07Å; F289-V314 HydrophobicContact CZ-CG2 4.35Å; F289-L338 HydrophobicContact CB-CD1 4.01Å; F289-L338 HydrophobicContact CB-CD2 3.86Å
290	R	97.5	Very high	94.2	Very high	64 Å²	64	42.3 Å²	42.3	24%	0.242	19%	0.192	C	C	.	.	H	α-helix	trans	-57.6	-47.6	174	175.2	169.8	-178.6	171.8	4.9	111.2	L286 A288 F292 L293 E294 D334 F337	L286-R290 PolarHBondContact O-N 3.18Å; A288-R290 VanDerWaalsContact C-N 3.35Å; A288-R290 PolarHBondContact O-N 2.85Å; R290-F292 PolarHBondContact O-N 3.4Å; R290-L293 PolarHBondContact O-N 3.3Å; R290-L293 VanDerWaalsContact O-N 3.17Å; R290-E294 IonicContact CZ-OE2 2.72Å; R290-E294 IonicContact NE-OE2 2.75Å; R290-E294 PolarHBondContact NE-OE2 2.93Å; R290-E294 VanDerWaalsContact NE-OE2 3.07Å; R290-E294 IonicContact NH2-OE2 3.6Å; R290-E294 VanDerWaalsContact O-CB 3.23Å; R290-E294 WeakPolarHBondContact O-CB 3.44Å; R290-E294 PolarHBondContact O-N 2.76Å; R290-D334 WeakPolarHBondContact CD-OD1 3.42Å; R290-D334 IonicContact CZ-OD1 3.92Å; R290-D334 IonicContact NE-OD1 3.28Å; R290-D334 IonicContact NH1-OD1 3.45Å; R290-D334 PolarHBondContact NH1-OD1 3.32Å; R290-F337 HydrophobicContact CB-CD1 4.17Å; R290-F337 HydrophobicContact CB-CE1 4.27Å; R290-F337 HydrophobicContact CG-CD1 3.71Å; R290-F337 HydrophobicContact CG-CE1 3.69Å; R290-F337 HydrophobicContact CG-CG 4.42Å; R290-F337 HydrophobicContact CG-CZ 4.36Å
291	N	96.4	Very high	93.9	Very high	11 Å²	11	39 Å²	39	6%	0.059	18%	0.178	C	C	.	.	H	α-helix	trans	-59.4	-43.4	177.7	-86.3	0.2	0	0	0	112.5	W248 A251 F252 A287 A288 F289 L293 E294 K295	W248-N291 PolarHBondContact NE1-ND2 3.06Å; W248-N291 VanDerWaalsContact NE1-ND2 3.15Å; W248-N291 PolarHBondContact O-ND2 3.43Å; A251-N291 HydrophobicContact CB-CB 3.86Å; F252-N291 WeakPolarHBondContact CE2-ND2 3.44Å; A287-N291 WeakPolarHBondContact O-CB 3.23Å; A287-N291 PolarHBondContact O-N 3.27Å; A288-N291 PolarHBondContact O-N 3Å; F289-N291 VanDerWaalsContact C-N 3.34Å; F289-N291 PolarHBondContact O-N 3.17Å; N291-L293 VanDerWaalsContact C-N 3.27Å; N291-L293 PolarHBondContact O-N 2.91Å; N291-E294 PolarHBondContact O-N 3.49Å; N291-K295 HydrophobicContact CB-CG 4.37Å; N291-K295 VanDerWaalsContact O-CB 3.26Å; N291-K295 WeakPolarHBondContact O-CB 3.41Å; N291-K295 WeakPolarHBondContact O-CG 3.36Å; N291-K295 PolarHBondContact O-N 3.37Å
292	F	96.5	Very high	93.6	Very high	0 Å²	0	44 Å²	44	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-59.8	-36	177.1	-73.8	-57.5	0	0	0	112.8	I247 A251 L260 I265 I266 A288 F289 R290 S296 Y305 M309	I247-F292 HydrophobicContact CG2-CE2 4.09Å; I247-F292 HydrophobicContact CG2-CZ 3.7Å; A251-F292 HydrophobicContact CB-CD1 4.1Å; A251-F292 HydrophobicContact CB-CE1 3.85Å; A251-F292 HydrophobicContact CB-CZ 4.14Å; L260-F292 HydrophobicContact CB-CE1 4.17Å; L260-F292 HydrophobicContact CD1-CE1 3.83Å; L260-F292 HydrophobicContact CD1-CZ 4.38Å; I265-F292 HydrophobicContact CD1-CZ 4.17Å; I265-F292 HydrophobicContact CG2-CE2 3.98Å; I265-F292 HydrophobicContact CG2-CZ 3.93Å; I266-F292 HydrophobicContact CD1-CD2 3.68Å; I266-F292 HydrophobicContact CD1-CE2 4.04Å; I266-F292 HydrophobicContact CD1-CG 4.32Å; A288-F292 HydrophobicContact CB-CE2 4.44Å; A288-F292 WeakPolarHBondContact O-CD2 3.41Å; A288-F292 PolarHBondContact O-N 3.38Å; F289-F292 PolarHBondContact O-N 2.94Å; R290-F292 PolarHBondContact O-N 3.4Å; F292-S296 VanDerWaalsContact O-CB 3.25Å; F292-S296 WeakPolarHBondContact O-CB 3.41Å; F292-S296 PolarHBondContact O-OG 3.3Å; F292-Y305 HydrophobicContact CB-CD1 4.2Å; F292-Y305 HydrophobicContact CB-CD2 4.02Å; F292-Y305 HydrophobicContact CB-CE1 4.49Å; F292-Y305 HydrophobicContact CB-CE2 4.33Å; F292-Y305 HydrophobicContact CB-CG 3.97Å; F292-Y305 HydrophobicContact CD1-CD1 4.28Å; F292-Y305 HydrophobicContact CD1-CD2 4.36Å; F292-Y305 AromaticContact CD1-CE1 3.73Å; F292-Y305 HydrophobicContact CD1-CE1 3.73Å; F292-Y305 AromaticContact CD1-CE2 3.83Å; F292-Y305 HydrophobicContact CD1-CE2 3.83Å; F292-Y305 AromaticContact CD1-CZ 3.48Å; F292-Y305 VanDerWaalsContact CD1-CZ 3.48Å; F292-Y305 HydrophobicContact CE1-CE1 4.1Å; F292-Y305 AromaticContact CE1-CZ 3.92Å; F292-Y305 HydrophobicContact CG-CD1 4.24Å; F292-Y305 HydrophobicContact CG-CE1 4.12Å; F292-Y305 HydrophobicContact CG-CE2 4.44Å; F292-Y305 HydrophobicContact CG-CG 4.46Å; F292-M309 HydrophobicContact CB-CE 4.19Å
293	L	94.6	Very high	93.1	Very high	7 Å²	7	47.5 Å²	47.5	4%	0.037	21%	0.212	C	C	.	.	H	α-helix	trans	-82	-44.2	177.8	-62.2	-178.6	0	0	0	112.7	F289 R290 N291 R302 A306 M309 F337 L338 K341 L342	F289-L293 PolarHBondContact O-N 2.82Å; F289-L293 VanDerWaalsContact O-N 3.16Å; R290-L293 PolarHBondContact O-N 3.3Å; R290-L293 VanDerWaalsContact O-N 3.17Å; N291-L293 VanDerWaalsContact C-N 3.27Å; N291-L293 PolarHBondContact O-N 2.91Å; L293-R302 HydrophobicContact CD2-CG 4.22Å; L293-R302 WeakPolarHBondContact O-CD 3.23Å; L293-R302 PolarHBondContact O-NE 3.14Å; L293-R302 VanDerWaalsContact O-NE 3.07Å; L293-A306 HydrophobicContact CD2-CB 3.95Å; L293-M309 HydrophobicContact CD1-SD 4.14Å; L293-M309 HydrophobicContact CD2-CE 4.31Å; L293-M309 HydrophobicContact CG-CE 4.1Å; L293-M309 HydrophobicContact CG-SD 4.35Å; L293-F337 HydrophobicContact CB-CE1 4.45Å; L293-L338 HydrophobicContact CD1-CD2 3.86Å; L293-K341 HydrophobicContact CD1-CB 4.17Å; L293-L342 HydrophobicContact CD1-CD2 4.02Å; L293-L342 HydrophobicContact CD1-CG 4.39Å
294	E	94.7	Very high	92.7	Very high	81 Å²	81	46 Å²	46	38%	0.379	21%	0.21	S	C	.	.	H	α-helix	trans	-77.5	-39.4	-172.3	-162.1	-165.5	125.1	0	0	112.6	R290 N291 F337	R290-E294 IonicContact CZ-OE2 2.72Å; R290-E294 IonicContact NE-OE2 2.75Å; R290-E294 PolarHBondContact NE-OE2 2.93Å; R290-E294 VanDerWaalsContact NE-OE2 3.07Å; R290-E294 IonicContact NH2-OE2 3.6Å; R290-E294 VanDerWaalsContact O-CB 3.23Å; R290-E294 WeakPolarHBondContact O-CB 3.44Å; R290-E294 PolarHBondContact O-N 2.76Å; N291-E294 PolarHBondContact O-N 3.49Å; E294-F337 HydrophobicContact CB-CZ 4.09Å; E294-F337 HydrophobicContact CG-CZ 4.3Å
295	K	93.3	Very high	92.4	Very high	57 Å²	57	45.9 Å²	45.9	25%	0.248	21%	0.208	C	C	.	.	S	Bend	trans	-89.9	-15.6	-174.7	-53.4	-52	-178.3	-158.8	0	113.7	P254 N291 T297	P254-K295 WeakPolarHBondContact CB-O 3.02Å; P254-K295 WeakPolarHBondContact CG-O 3.43Å; N291-K295 HydrophobicContact CB-CG 4.37Å; N291-K295 VanDerWaalsContact O-CB 3.26Å; N291-K295 WeakPolarHBondContact O-CB 3.41Å; N291-K295 WeakPolarHBondContact O-CG 3.36Å; N291-K295 PolarHBondContact O-N 3.37Å; K295-T297 PolarHBondContact O-N 2.88Å
296	S	90.5	Very high	92.1	Very high	1 Å²	1	45.9 Å²	45.9	1%	0.007	21%	0.209	C	C	.	.			trans	-67.6	116	175	-67.7	0	0	0	0	110.7	F292 R302	F292-S296 VanDerWaalsContact O-CB 3.25Å; F292-S296 WeakPolarHBondContact O-CB 3.41Å; F292-S296 PolarHBondContact O-OG 3.3Å; S296-R302 PolarHBondContact O-NH2 2.9Å
297	T	87.8	Confident	91.6	Very high	92 Å²	92	47 Å²	47	56%	0.564	21%	0.214	S	C	*	.			trans	-76.8	-41	-179.7	39	0	0	0	0	112.3	P254 K295	P254-T297 HydrophobicContact CB-CG2 3.65Å; P254-T297 HydrophobicContact CG-CG2 3.97Å; K295-T297 PolarHBondContact O-N 2.88Å
298	E	87.5	Confident	91.2	Very high	80 Å²	80	47 Å²	47	37%	0.374	21%	0.214	S	C	.	.	S	Bend	trans	-75	131.9	178.7	-64.9	-173.8	150.2	0	0	111.5	E258 R261 E300 T301 R302	E258-E298 WeakPolarHBondContact OE1-CG 3.4Å; R261-E298 IonicContact NH2-OE2 3.86Å; R261-E298 PolarHBondContact NH2-OE2 2.91Å; E298-E300 VanDerWaalsContact C-N 3.32Å; E298-E300 PolarHBondContact O-N 3.48Å; E298-T301 PolarHBondContact O-N 2.86Å; E298-T301 PolarHBondContact OE2-OG1 3.28Å; E298-R302 PolarHBondContact O-N 3.49Å
299	R	85.8	Confident	90.9	Very high	168 Å²	168	47 Å²	47	63%	0.634	21%	0.214	S	C	*	.	H	α-helix	trans	-59.8	-43.3	176.7	-176.6	-180	178.5	173.9	4.3	111.6	R302 Q303	R299-R302 PolarHBondContact O-N 3.24Å; R299-Q303 HydrophobicContact CG-CG 4.38Å; R299-Q303 WeakPolarHBondContact O-CB 3.43Å; R299-Q303 VanDerWaalsContact O-CG 3.31Å; R299-Q303 WeakPolarHBondContact O-CG 3.08Å; R299-Q303 PolarHBondContact O-N 3.43Å
300	E	83.9	Confident	90.5	Very high	130 Å²	130	48.5 Å²	48.5	61%	0.607	22%	0.222	S	C	*	.	H	α-helix	trans	-61	-47.2	179.6	-62.9	-176	-174.5	0	0	111.2	E298 R302 Q303 E304	E298-E300 VanDerWaalsContact C-N 3.32Å; E298-E300 PolarHBondContact O-N 3.48Å; E300-R302 PolarHBondContact O-N 3.46Å; E300-Q303 PolarHBondContact O-N 3Å; E300-E304 WeakPolarHBondContact O-CG 3.09Å; E300-E304 PolarHBondContact O-N 3.22Å
301	T	87.8	Confident	89.8	Confident	1 Å²	1	47.2 Å²	47.2	1%	0.006	22%	0.219	C	C	.	.	H	α-helix	trans	-58.4	-46.2	176.6	-65.6	0	0	0	0	111.9	E258 R261 E298 E304 Y305	E258-T301 HydrophobicContact CG-CG2 4.46Å; R261-T301 HydrophobicContact CG-CG2 4.08Å; R261-T301 PolarHBondContact NE-OG1 3.48Å; R261-T301 PolarHBondContact NH1-OG1 2.81Å; R261-T301 PolarHBondContact NH2-OG1 3.44Å; E298-T301 PolarHBondContact O-N 2.86Å; E298-T301 PolarHBondContact OE2-OG1 3.28Å; T301-E304 PolarHBondContact O-N 3.36Å; T301-Y305 HydrophobicContact CG2-CD2 3.95Å; T301-Y305 HydrophobicContact CG2-CE2 3.61Å; T301-Y305 WeakPolarHBondContact O-CD2 3.27Å; T301-Y305 PolarHBondContact O-N 3.5Å; T301-Y305 VanDerWaalsContact O-N 3.14Å
302	R	89.8	Confident	89.5	Confident	105 Å²	105	47.2 Å²	47.2	40%	0.396	22%	0.22	S	C	.	.	H	α-helix	trans	-62.7	-43.4	177.6	-172.6	-174.2	-57.6	138.6	10.6	111.7	L293 S296 E298 R299 E300 Y305 A306	L293-R302 HydrophobicContact CD2-CG 4.22Å; L293-R302 WeakPolarHBondContact O-CD 3.23Å; L293-R302 PolarHBondContact O-NE 3.14Å; L293-R302 VanDerWaalsContact O-NE 3.07Å; S296-R302 PolarHBondContact O-NH2 2.9Å; E298-R302 PolarHBondContact O-N 3.49Å; R299-R302 PolarHBondContact O-N 3.24Å; E300-R302 PolarHBondContact O-N 3.46Å; R302-Y305 PolarHBondContact O-N 3.01Å; R302-A306 PolarHBondContact O-N 3.37Å
303	Q	85.8	Confident	89.1	Confident	80 Å²	80	52 Å²	52	37%	0.374	24%	0.241	S	C	.	.	H	α-helix	trans	-61.5	-47.8	177.3	-76.3	175.6	-29.1	0	0	110.6	R299 E300 Y305 A306 L307	R299-Q303 HydrophobicContact CG-CG 4.38Å; R299-Q303 WeakPolarHBondContact O-CB 3.43Å; R299-Q303 VanDerWaalsContact O-CG 3.31Å; R299-Q303 WeakPolarHBondContact O-CG 3.08Å; R299-Q303 PolarHBondContact O-N 3.43Å; E300-Q303 PolarHBondContact O-N 3Å; Q303-Y305 VanDerWaalsContact C-N 3.29Å; Q303-Y305 PolarHBondContact O-N 2.83Å; Q303-A306 PolarHBondContact O-N 2.97Å; Q303-A306 VanDerWaalsContact O-N 3.11Å; Q303-L307 VanDerWaalsContact O-CG 3.26Å; Q303-L307 WeakPolarHBondContact O-CG 3.21Å; Q303-L307 PolarHBondContact O-N 2.91Å
304	E	87.1	Confident	89.1	Confident	63 Å²	63	51.7 Å²	51.7	29%	0.294	24%	0.239	S	C	.	.	H	α-helix	trans	-56.7	-41.4	177.5	-73.4	-175.9	155.8	0	0	112.5	R261 E300 T301 A308 K360	R261-E304 WeakPolarHBondContact CD-OE2 3.4Å; R261-E304 IonicContact CZ-OE2 3.93Å; R261-E304 IonicContact NE-OE2 3.55Å; R261-E304 IonicContact NH1-OE2 3.73Å; R261-E304 PolarHBondContact NH1-OE2 3.17Å; E300-E304 WeakPolarHBondContact O-CG 3.09Å; E300-E304 PolarHBondContact O-N 3.22Å; T301-E304 PolarHBondContact O-N 3.36Å; E304-A308 WeakPolarHBondContact O-CB 3.4Å; E304-A308 PolarHBondContact O-N 3.25Å; E304-K360 IonicContact OE1-NZ 3.45Å; E304-K360 PolarHBondContact OE1-NZ 3Å
305	Y	92.3	Very high	88.9	Confident	8 Å²	8	49.3 Å²	49.3	3%	0.031	23%	0.229	C	C	.	.	H	α-helix	trans	-65.1	-44.8	174.4	-75.6	-54.3	0	0	0	113.1	C257 R261 I266 F292 T301 R302 Q303 A308 M309	C257-Y305 HydrophobicContact CB-CE2 4.37Å; C257-Y305 PolarHBondContact O-OH 2.97Å; R261-Y305 HydrophobicContact CG-CE1 4.13Å; R261-Y305 HydrophobicContact CG-CE2 3.81Å; R261-Y305 WeakPolarHBondContact CG-OH 3.16Å; R261-Y305 PolarHBondContact N-OH 3.04Å; R261-Y305 VanDerWaalsContact N-OH 3.1Å; I266-Y305 HydrophobicContact CD1-CD1 3.96Å; I266-Y305 HydrophobicContact CD1-CE1 4.45Å; I266-Y305 HydrophobicContact CG1-CD1 3.71Å; I266-Y305 HydrophobicContact CG1-CE1 4.26Å; F292-Y305 HydrophobicContact CB-CD1 4.2Å; F292-Y305 HydrophobicContact CB-CD2 4.02Å; F292-Y305 HydrophobicContact CB-CE1 4.49Å; F292-Y305 HydrophobicContact CB-CE2 4.33Å; F292-Y305 HydrophobicContact CB-CG 3.97Å; F292-Y305 HydrophobicContact CD1-CD1 4.28Å; F292-Y305 HydrophobicContact CD1-CD2 4.36Å; F292-Y305 AromaticContact CD1-CE1 3.73Å; F292-Y305 HydrophobicContact CD1-CE1 3.73Å; F292-Y305 AromaticContact CD1-CE2 3.83Å; F292-Y305 HydrophobicContact CD1-CE2 3.83Å; F292-Y305 AromaticContact CD1-CZ 3.48Å; F292-Y305 VanDerWaalsContact CD1-CZ 3.48Å; F292-Y305 HydrophobicContact CE1-CE1 4.1Å; F292-Y305 AromaticContact CE1-CZ 3.92Å; F292-Y305 HydrophobicContact CG-CD1 4.24Å; F292-Y305 HydrophobicContact CG-CE1 4.12Å; F292-Y305 HydrophobicContact CG-CE2 4.44Å; F292-Y305 HydrophobicContact CG-CG 4.46Å; T301-Y305 HydrophobicContact CG2-CD2 3.95Å; T301-Y305 HydrophobicContact CG2-CE2 3.61Å; T301-Y305 WeakPolarHBondContact O-CD2 3.27Å; T301-Y305 PolarHBondContact O-N 3.5Å; T301-Y305 VanDerWaalsContact O-N 3.14Å; R302-Y305 PolarHBondContact O-N 3.01Å; Q303-Y305 VanDerWaalsContact C-N 3.29Å; Q303-Y305 PolarHBondContact O-N 2.83Å; Y305-A308 PolarHBondContact O-N 3.21Å; Y305-M309 WeakPolarHBondContact O-CG 3.19Å; Y305-M309 PolarHBondContact O-N 3.02Å
306	A	91.2	Very high	88.8	Confident	1 Å²	1	53.1 Å²	53.1	1%	0.008	25%	0.245	C	C	.	.	H	α-helix	trans	-61.4	-44.9	178.1	0	0	0	0	0	111.5	L293 R302 Q303 M309 I310 L342	L293-A306 HydrophobicContact CD2-CB 3.95Å; R302-A306 PolarHBondContact O-N 3.37Å; Q303-A306 PolarHBondContact O-N 2.97Å; Q303-A306 VanDerWaalsContact O-N 3.11Å; A306-M309 PolarHBondContact O-N 2.83Å; A306-I310 WeakPolarHBondContact O-CD1 3.41Å; A306-I310 VanDerWaalsContact O-CG1 3.26Å; A306-I310 WeakPolarHBondContact O-CG1 3.4Å; A306-I310 PolarHBondContact O-N 3.3Å; A306-L342 HydrophobicContact CB-CD2 3.88Å
307	L	86.6	Confident	88.9	Confident	22 Å²	22	54 Å²	54	12%	0.115	25%	0.249	C	C	.	.	H	α-helix	trans	-62.2	-44.9	177.4	-63.2	-175.5	0	0	0	112	Q303 M309 I310 Q311 L349 D353	Q303-L307 VanDerWaalsContact O-CG 3.26Å; Q303-L307 WeakPolarHBondContact O-CG 3.21Å; Q303-L307 PolarHBondContact O-N 2.91Å; L307-M309 VanDerWaalsContact C-N 3.29Å; L307-M309 PolarHBondContact O-N 3.24Å; L307-I310 HydrophobicContact CD2-CD1 4.39Å; L307-I310 PolarHBondContact O-N 3.39Å; L307-Q311 WeakPolarHBondContact O-CB 3.23Å; L307-Q311 WeakPolarHBondContact O-CG 3.37Å; L307-Q311 PolarHBondContact O-N 3.09Å; L307-L349 HydrophobicContact CD1-CD1 4.2Å; L307-L349 HydrophobicContact CD2-CB 4.45Å; L307-L349 HydrophobicContact CD2-CD1 3.28Å; L307-L349 HydrophobicContact CD2-CD2 3.74Å; L307-L349 HydrophobicContact CD2-CG 3.99Å; L307-L349 HydrophobicContact CG-CD1 4.36Å; L307-D353 HydrophobicContact CD1-CB 3.86Å
308	A	89.5	Confident	89.3	Confident	15 Å²	15	49.7 Å²	49.7	12%	0.124	22%	0.222	C	C	.	.	H	α-helix	trans	-59.1	-41.1	175.8	0	0	0	0	0	111.9	I266 E304 Y305 C312	I266-A308 HydrophobicContact CB-CB 3.98Å; I266-A308 HydrophobicContact CG1-CB 4.24Å; I266-A308 HydrophobicContact CG2-CB 3.91Å; E304-A308 WeakPolarHBondContact O-CB 3.4Å; E304-A308 PolarHBondContact O-N 3.25Å; Y305-A308 PolarHBondContact O-N 3.21Å; A308-C312 WeakPolarHBondContact O-CB 3.5Å; A308-C312 PolarHBondContact O-N 3.37Å; A308-C312 PolarHBondContact O-SG 3.15Å
309	M	93.3	Very high	89.6	Confident	0 Å²	0	50.6 Å²	50.6	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-66	-43	176.8	-69.8	176.8	-161.1	0	0	111.9	I266 F289 F292 L293 Y305 A306 L307 C312 K313 V314 L342	I266-M309 HydrophobicContact CD1-CE 3.65Å; I266-M309 HydrophobicContact CD1-CG 4.41Å; I266-M309 HydrophobicContact CG2-CB 4.27Å; I266-M309 HydrophobicContact CG2-CG 3.56Å; F289-M309 HydrophobicContact CB-CE 3.61Å; F289-M309 HydrophobicContact CB-SD 3.97Å; F289-M309 HydrophobicContact CD1-CE 3.65Å; F289-M309 HydrophobicContact CD1-SD 4.33Å; F289-M309 HydrophobicContact CE1-CE 4.49Å; F289-M309 HydrophobicContact CG-CE 3.79Å; F289-M309 HydrophobicContact CG-SD 4.06Å; F292-M309 HydrophobicContact CB-CE 4.19Å; L293-M309 HydrophobicContact CD1-SD 4.14Å; L293-M309 HydrophobicContact CD2-CE 4.31Å; L293-M309 HydrophobicContact CG-CE 4.1Å; L293-M309 HydrophobicContact CG-SD 4.35Å; Y305-M309 WeakPolarHBondContact O-CG 3.19Å; Y305-M309 PolarHBondContact O-N 3.02Å; A306-M309 PolarHBondContact O-N 2.83Å; L307-M309 VanDerWaalsContact C-N 3.29Å; L307-M309 PolarHBondContact O-N 3.24Å; M309-C312 PolarHBondContact O-N 2.87Å; M309-K313 PolarHBondContact O-N 2.75Å; M309-V314 HydrophobicContact CB-CB 4.11Å; M309-V314 HydrophobicContact CB-CG2 4.12Å; M309-V314 WeakPolarHBondContact O-CB 3.32Å; M309-V314 VanDerWaalsContact O-CG2 3.26Å; M309-V314 WeakPolarHBondContact O-CG2 3.13Å; M309-V314 PolarHBondContact O-N 2.65Å; M309-L342 HydrophobicContact CB-CD1 4.06Å; M309-L342 HydrophobicContact CB-CD2 3.95Å; M309-L342 HydrophobicContact SD-CD1 4.29Å; M309-L342 HydrophobicContact SD-CD2 4.02Å
310	I	87.8	Confident	89.9	Confident	32 Å²	32	46.4 Å²	46.4	16%	0.164	22%	0.217	C	C	.	.	H	α-helix	trans	-60.1	-47.9	177.7	-69.1	160.5	0	0	0	110.3	A306 L307 C312 K313 L315 L342 V346	A306-I310 WeakPolarHBondContact O-CD1 3.41Å; A306-I310 VanDerWaalsContact O-CG1 3.26Å; A306-I310 WeakPolarHBondContact O-CG1 3.4Å; A306-I310 PolarHBondContact O-N 3.3Å; L307-I310 HydrophobicContact CD2-CD1 4.39Å; L307-I310 PolarHBondContact O-N 3.39Å; I310-C312 VanDerWaalsContact C-N 3.33Å; I310-C312 PolarHBondContact O-N 3.39Å; I310-K313 WeakPolarHBondContact O-CA 3.34Å; I310-K313 PolarHBondContact O-N 3.07Å; I310-L315 HydrophobicContact CG1-CD1 3.94Å; I310-L342 HydrophobicContact CG1-CD2 4.39Å; I310-V346 HydrophobicContact CD1-CG2 3.59Å; I310-V346 HydrophobicContact CG1-CG2 3.93Å; I310-V346 HydrophobicContact CG2-CG2 4.21Å
311	Q	84.6	Confident	90.3	Very high	38 Å²	38	41.2 Å²	41.2	18%	0.178	19%	0.193	C	C	.	.	H	α-helix	trans	-64.9	-37.2	-179.9	-72.9	-179.5	-21.4	0	0	113	L307 K313 E354 S357 E358	L307-Q311 WeakPolarHBondContact O-CB 3.23Å; L307-Q311 WeakPolarHBondContact O-CG 3.37Å; L307-Q311 PolarHBondContact O-N 3.09Å; Q311-K313 PolarHBondContact O-N 3.46Å; Q311-E354 PolarHBondContact NE2-O 3.44Å; Q311-S357 VanDerWaalsContact CD-OG 3.24Å; Q311-S357 VanDerWaalsContact NE2-CB 3.27Å; Q311-S357 PolarHBondContact NE2-OG 3Å; Q311-S357 VanDerWaalsContact OE1-CB 3.29Å; Q311-S357 PolarHBondContact OE1-O 3.07Å; Q311-S357 PolarHBondContact OE1-OG 3.24Å; Q311-E358 HydrophobicContact CG-CG 4.49Å
312	C	89.3	Confident	90.6	Very high	11 Å²	11	46.2 Å²	46.2	7%	0.074	22%	0.216	C	C	.	.	T	Hydrogen-bonded Turn	trans	-76.4	15.2	173.8	-59.7	0	0	0	0	112.9	S270 A308 M309 I310 V314	S270-C312 VanDerWaalsContact OG-CB 3.32Å; S270-C312 WeakPolarHBondContact OG-CB 3.3Å; A308-C312 WeakPolarHBondContact O-CB 3.5Å; A308-C312 PolarHBondContact O-N 3.37Å; A308-C312 PolarHBondContact O-SG 3.15Å; M309-C312 PolarHBondContact O-N 2.87Å; I310-C312 VanDerWaalsContact C-N 3.33Å; I310-C312 PolarHBondContact O-N 3.39Å; C312-V314 HydrophobicContact CB-CG2 4.3Å; C312-V314 PolarHBondContact O-N 3.37Å; C312-V314 VanDerWaalsContact O-N 3.15Å
313	K	88.9	Confident	90.7	Very high	101 Å²	101	48.8 Å²	48.8	44%	0.439	23%	0.233	S	C	.	.	T	Hydrogen-bonded Turn	trans	59.5	25.5	174.9	-61.9	164.7	-178.9	156	0	113.1	M309 I310 Q311 L315 K316 Q317 E365	M309-K313 PolarHBondContact O-N 2.75Å; I310-K313 WeakPolarHBondContact O-CA 3.34Å; I310-K313 PolarHBondContact O-N 3.07Å; Q311-K313 PolarHBondContact O-N 3.46Å; K313-L315 VanDerWaalsContact C-N 3.29Å; K313-L315 PolarHBondContact O-N 3.37Å; K313-K316 PolarHBondContact O-N 3.42Å; K313-Q317 WeakPolarHBondContact O-CG 3.3Å; K313-Q317 PolarHBondContact O-N 2.78Å; K313-E365 IonicContact NZ-OE1 3.57Å; K313-E365 PolarHBondContact NZ-OE1 3.28Å; K313-E365 IonicContact NZ-OE2 2.74Å; K313-E365 PolarHBondContact NZ-OE2 2.58Å
314	V	93.8	Very high	90.9	Very high	0 Å²	0	50.2 Å²	50.2	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-62.2	-37	-179.2	176.2	0	0	0	0	111	S270 F289 M309 C312 K316 Q317 L318 L342	S270-V314 WeakPolarHBondContact OG-CG2 3.5Å; F289-V314 HydrophobicContact CD2-CG1 4.17Å; F289-V314 HydrophobicContact CE2-CG1 3.98Å; F289-V314 HydrophobicContact CE2-CG2 4.07Å; F289-V314 HydrophobicContact CZ-CG2 4.35Å; M309-V314 HydrophobicContact CB-CB 4.11Å; M309-V314 HydrophobicContact CB-CG2 4.12Å; M309-V314 WeakPolarHBondContact O-CB 3.32Å; M309-V314 VanDerWaalsContact O-CG2 3.26Å; M309-V314 WeakPolarHBondContact O-CG2 3.13Å; M309-V314 PolarHBondContact O-N 2.65Å; C312-V314 HydrophobicContact CB-CG2 4.3Å; C312-V314 PolarHBondContact O-N 3.37Å; C312-V314 VanDerWaalsContact O-N 3.15Å; V314-K316 PolarHBondContact O-N 3.11Å; V314-Q317 CarbonylContact O-C 3.43Å; V314-Q317 WeakPolarHBondContact O-CA 3.28Å; V314-Q317 WeakPolarHBondContact O-CB 3.35Å; V314-Q317 PolarHBondContact O-N 3.42Å; V314-L318 HydrophobicContact CG1-CD1 3.89Å; V314-L318 HydrophobicContact CG1-CG 3.99Å; V314-L318 VanDerWaalsContact O-CG 3.29Å; V314-L318 WeakPolarHBondContact O-CG 3.5Å; V314-L318 PolarHBondContact O-N 3.45Å; V314-L342 HydrophobicContact CG1-CD1 4.31Å
315	L	90.9	Very high	90.9	Very high	31 Å²	31	57.1 Å²	57.1	16%	0.162	27%	0.269	C	S	.	.	H	α-helix	trans	-53.5	-51.5	176	-85.4	174.1	0	0	0	112.7	I310 K313 Q317 L318 E319 L339 L342 V346	I310-L315 HydrophobicContact CG1-CD1 3.94Å; K313-L315 VanDerWaalsContact C-N 3.29Å; K313-L315 PolarHBondContact O-N 3.37Å; L315-Q317 VanDerWaalsContact C-N 3.27Å; L315-Q317 PolarHBondContact O-N 2.88Å; L315-L318 WeakPolarHBondContact O-CB 3.47Å; L315-L318 PolarHBondContact O-N 3.2Å; L315-L318 VanDerWaalsContact O-N 3.15Å; L315-E319 WeakPolarHBondContact O-CG 3.36Å; L315-E319 PolarHBondContact O-N 3.15Å; L315-L339 HydrophobicContact CD2-CD2 4.24Å; L315-L342 HydrophobicContact CD1-CB 4.25Å; L315-L342 HydrophobicContact CD2-CB 3.42Å; L315-L342 VanDerWaalsContact CD2-CB 3.42Å; L315-L342 HydrophobicContact CD2-CD1 4.12Å; L315-L342 HydrophobicContact CD2-CG 4.43Å; L315-L342 HydrophobicContact CG-CB 3.85Å; L315-L342 HydrophobicContact CG-CD1 4.18Å; L315-V346 HydrophobicContact CD1-CG2 3.48Å; L315-V346 VanDerWaalsContact CD1-CG2 3.48Å
316	K	90.7	Very high	90.8	Very high	136 Å²	136	58.3 Å²	58.3	59%	0.591	27%	0.273	S	S	*	.	H	α-helix	trans	-62.4	-36.7	177.3	-175.8	178	-179	179.7	0	111.8	K313 V314 N320	K313-K316 PolarHBondContact O-N 3.42Å; V314-K316 PolarHBondContact O-N 3.11Å; K316-N320 PolarHBondContact O-N 3.42Å; K316-N320 PolarHBondContact O-ND2 3.43Å; K316-N320 VanDerWaalsContact O-ND2 3.14Å
317	Q	93.4	Very high	90.8	Very high	21 Å²	21	66.3 Å²	66.3	10%	0.098	32%	0.316	C	S	.	.	H	α-helix	trans	-64.8	-43.8	175.3	-64.3	176.8	12.1	0	0	111	K313 V314 L315 E319 N320 L321	K313-Q317 WeakPolarHBondContact O-CG 3.3Å; K313-Q317 PolarHBondContact O-N 2.78Å; V314-Q317 CarbonylContact O-C 3.43Å; V314-Q317 WeakPolarHBondContact O-CA 3.28Å; V314-Q317 WeakPolarHBondContact O-CB 3.35Å; V314-Q317 PolarHBondContact O-N 3.42Å; L315-Q317 VanDerWaalsContact C-N 3.27Å; L315-Q317 PolarHBondContact O-N 2.88Å; Q317-E319 PolarHBondContact O-N 2.89Å; Q317-N320 WeakPolarHBondContact O-CB 3.31Å; Q317-N320 PolarHBondContact O-N 3.29Å; Q317-L321 VanDerWaalsContact O-CG 3.26Å; Q317-L321 WeakPolarHBondContact O-CG 3.07Å; Q317-L321 PolarHBondContact O-N 3.12Å
318	L	95.4	Very high	91	Very high	0 Å²	0	67.1 Å²	67.1	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-61.9	-42.6	177.5	-67.2	169	0	0	0	112.2	L286 V314 L315 N320 L321 E322 I335 L338 L339 L342	L286-L318 HydrophobicContact CD2-CD2 3.46Å; L286-L318 VanDerWaalsContact CD2-CD2 3.46Å; V314-L318 HydrophobicContact CG1-CD1 3.89Å; V314-L318 HydrophobicContact CG1-CG 3.99Å; V314-L318 VanDerWaalsContact O-CG 3.29Å; V314-L318 WeakPolarHBondContact O-CG 3.5Å; V314-L318 PolarHBondContact O-N 3.45Å; L315-L318 WeakPolarHBondContact O-CB 3.47Å; L315-L318 PolarHBondContact O-N 3.2Å; L315-L318 VanDerWaalsContact O-N 3.15Å; L318-N320 VanDerWaalsContact C-N 3.3Å; L318-N320 PolarHBondContact O-N 3.49Å; L318-L321 PolarHBondContact O-N 3.03Å; L318-L321 VanDerWaalsContact O-N 3.16Å; L318-E322 WeakPolarHBondContact O-CB 3.45Å; L318-E322 PolarHBondContact O-N 3.12Å; L318-I335 HydrophobicContact CD2-CG1 4.22Å; L318-L338 HydrophobicContact CD1-CB 3.54Å; L318-L338 HydrophobicContact CD1-CD1 4.44Å; L318-L338 HydrophobicContact CD2-CB 4.3Å; L318-L338 HydrophobicContact CD2-CD1 4.03Å; L318-L339 HydrophobicContact CB-CD2 3.62Å; L318-L339 HydrophobicContact CB-CG 3.91Å; L318-L339 HydrophobicContact CD1-CD2 4.36Å; L318-L339 HydrophobicContact CD1-CG 4.43Å; L318-L342 HydrophobicContact CD1-CD1 3.95Å
319	E	93.6	Very high	91.2	Very high	100 Å²	100	73.6 Å²	73.6	47%	0.467	35%	0.348	S	S	.	.	H	α-helix	trans	-59.7	-40.3	174.2	-69.3	170.3	170.1	0	0	111.9	L315 Q317 Q323 L339	L315-E319 WeakPolarHBondContact O-CG 3.36Å; L315-E319 PolarHBondContact O-N 3.15Å; Q317-E319 PolarHBondContact O-N 2.89Å; E319-Q323 WeakPolarHBondContact O-CG 3.46Å; E319-Q323 PolarHBondContact O-N 3.1Å; E319-L339 HydrophobicContact CG-CD2 4.02Å
320	N	92.6	Very high	91.2	Very high	79 Å²	79	76.8 Å²	76.8	42%	0.422	37%	0.366	S	S	.	.	H	α-helix	trans	-68.4	-37.6	175.6	-66	-29	0	0	0	112	K316 Q317 L318	K316-N320 PolarHBondContact O-N 3.42Å; K316-N320 PolarHBondContact O-ND2 3.43Å; K316-N320 VanDerWaalsContact O-ND2 3.14Å; Q317-N320 WeakPolarHBondContact O-CB 3.31Å; Q317-N320 PolarHBondContact O-N 3.29Å; L318-N320 VanDerWaalsContact C-N 3.3Å; L318-N320 PolarHBondContact O-N 3.49Å
321	L	92.8	Very high	91.5	Very high	22 Å²	22	75.3 Å²	75.3	12%	0.115	36%	0.358	C	S	.	.	H	α-helix	trans	-69.2	-38.8	176.8	-66.3	169.1	0	0	0	110.8	L273 T282 Q317 L318 Q323 Q324 Y326 I335	L273-L321 HydrophobicContact CD1-CD1 4.22Å; T282-L321 HydrophobicContact CG2-CD1 4.32Å; T282-L321 HydrophobicContact CG2-CD2 4.43Å; Q317-L321 VanDerWaalsContact O-CG 3.26Å; Q317-L321 WeakPolarHBondContact O-CG 3.07Å; Q317-L321 PolarHBondContact O-N 3.12Å; L318-L321 PolarHBondContact O-N 3.03Å; L318-L321 VanDerWaalsContact O-N 3.16Å; L321-Q323 PolarHBondContact O-N 3.33Å; L321-Q324 WeakPolarHBondContact O-CB 3.42Å; L321-Q324 PolarHBondContact O-N 3.14Å; L321-Y326 HydrophobicContact CB-CE2 4.48Å; L321-Y326 WeakPolarHBondContact CD2-OH 3.34Å; L321-Y326 WeakPolarHBondContact O-CE2 3.42Å; L321-I335 HydrophobicContact CB-CD1 3.78Å
322	E	94.1	Very high	92	Very high	105 Å²	105	75.3 Å²	75.3	49%	0.491	36%	0.362	S	S	.	.	H	α-helix	trans	-60.9	-30.7	178.1	-171.6	177.7	-141.7	0	0	112.8	L318 Q324 I335 L339	L318-E322 WeakPolarHBondContact O-CB 3.45Å; L318-E322 PolarHBondContact O-N 3.12Å; E322-Q324 PolarHBondContact O-N 3.27Å; E322-I335 HydrophobicContact CB-CG2 3.95Å; E322-I335 HydrophobicContact CG-CG2 4.43Å; E322-L339 HydrophobicContact CB-CD1 4.36Å; E322-L339 WeakPolarHBondContact OE2-CD1 3.37Å
323	Q	91.8	Very high	92.3	Very high	159 Å²	159	79.8 Å²	79.8	74%	0.743	38%	0.382	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.3	-17.4	175.1	-67.7	172.2	22.6	0	0	113.1	E319 L321	E319-Q323 WeakPolarHBondContact O-CG 3.46Å; E319-Q323 PolarHBondContact O-N 3.1Å; L321-Q323 PolarHBondContact O-N 3.33Å
324	Q	89.3	Confident	92.7	Very high	111 Å²	111	75.5 Å²	75.5	52%	0.519	36%	0.364	S	S	.	.	S	Bend	trans	-86.1	148.5	176.9	-57.5	-178.6	5.4	0	0	110.3	L321 E322 Y326	L321-Q324 WeakPolarHBondContact O-CB 3.42Å; L321-Q324 PolarHBondContact O-N 3.14Å; E322-Q324 PolarHBondContact O-N 3.27Å; Q324-Y326 HydrophobicContact CB-CE2 3.88Å; Q324-Y326 PolarHBondContact OE1-OH 3.13Å
325	K	87.1	Confident	92.9	Very high	208 Å²	208	75.7 Å²	75.7	90%	0.904	37%	0.365	S	S	*	.			trans	-91.6	121.2	174.5	-68.8	-173	178.1	-174.7	0	109.5
326	Y	89.8	Confident	93.2	Very high	32 Å²	32	80.5 Å²	80.5	13%	0.125	38%	0.384	C	S	.	.			trans	-111.4	137.6	171.9	-63.9	-77.9	0	0	0	109.8	E279 L321 Q324 D328 I331 I335	E279-Y326 HydrophobicContact CG-CD1 4.44Å; E279-Y326 HydrophobicContact CG-CE1 4.25Å; L321-Y326 HydrophobicContact CB-CE2 4.48Å; L321-Y326 WeakPolarHBondContact CD2-OH 3.34Å; L321-Y326 WeakPolarHBondContact O-CE2 3.42Å; Q324-Y326 HydrophobicContact CB-CE2 3.88Å; Q324-Y326 PolarHBondContact OE1-OH 3.13Å; Y326-D328 VanDerWaalsContact C-N 3.29Å; Y326-I331 HydrophobicContact CD1-CD1 4.13Å; Y326-I331 HydrophobicContact CD1-CG2 4.21Å; Y326-I331 HydrophobicContact CD2-CG2 3.77Å; Y326-I331 HydrophobicContact CE1-CG2 4.45Å; Y326-I331 HydrophobicContact CE2-CG2 4.03Å; Y326-I331 HydrophobicContact CG-CB 4.48Å; Y326-I331 HydrophobicContact CG-CG2 3.85Å; Y326-I335 HydrophobicContact CD2-CD1 4.44Å; Y326-I335 HydrophobicContact CE2-CD1 4.12Å
327	D	90.8	Very high	93.5	Very high	169 Å²	169	75.9 Å²	75.9	90%	0.904	36%	0.364	S	S	*	.	S	Bend	trans	-78.6	-19.3	169.8	-66	-30.4	0	0	0	111.6	E329	D327-E329 PolarHBondContact O-N 2.58Å
328	D	91.4	Very high	93.7	Very high	40 Å²	40	74.9 Å²	74.9	21%	0.214	36%	0.36	C	S	.	.			trans	-79.7	108.3	178.3	-168.6	-14.6	0	0	0	111.1	R283 Y326 D330 I331 S332	R283-D328 WeakPolarHBondContact CD-OD2 3.39Å; R283-D328 IonicContact CZ-OD1 3.65Å; R283-D328 IonicContact CZ-OD2 2.75Å; R283-D328 IonicContact NE-OD2 3.8Å; R283-D328 IonicContact NH1-OD1 3.69Å; R283-D328 PolarHBondContact NH1-OD1 2.78Å; R283-D328 IonicContact NH1-OD2 2.78Å; R283-D328 PolarHBondContact NH1-OD2 2.83Å; Y326-D328 VanDerWaalsContact C-N 3.29Å; D328-D330 VanDerWaalsContact C-N 3.28Å; D328-D330 PolarHBondContact O-N 3.48Å; D328-D330 PolarHBondContact OD1-N 3.26Å; D328-D330 VanDerWaalsContact OD1-N 3.15Å; D328-I331 HydrophobicContact CB-CB 4.33Å; D328-I331 HydrophobicContact CB-CD1 3.87Å; D328-I331 HydrophobicContact CB-CG1 3.98Å; D328-I331 PolarHBondContact O-N 3.21Å; D328-S332 PolarHBondContact O-N 3.42Å
329	E	93.6	Very high	93.7	Very high	150 Å²	150	76.3 Å²	76.3	70%	0.701	37%	0.367	S	S	*	.	H	α-helix	trans	-61.3	-35.4	-179.5	-66	-175.9	169.6	0	0	112.1	D327 I331 S332 E333	D327-E329 PolarHBondContact O-N 2.58Å; E329-I331 VanDerWaalsContact C-N 3.32Å; E329-I331 PolarHBondContact O-N 2.96Å; E329-S332 WeakPolarHBondContact O-CB 3.48Å; E329-S332 PolarHBondContact O-N 3.42Å; E329-S332 VanDerWaalsContact O-N 3.13Å; E329-E333 WeakPolarHBondContact O-CG 3.44Å; E329-E333 PolarHBondContact O-N 3.23Å
330	D	93.1	Very high	93.7	Very high	68 Å²	68	76.8 Å²	76.8	36%	0.364	37%	0.37	S	S	.	.	H	α-helix	trans	-64.9	-37.8	-178.6	-70.4	-32.3	0	0	0	111.4	R283 D328 S332 E333 D334	R283-D330 IonicContact CZ-OD2 2.65Å; R283-D330 IonicContact NH1-OD2 3.45Å; R283-D330 PolarHBondContact NH1-OD2 3.05Å; R283-D330 IonicContact NH2-OD2 3.3Å; R283-D330 PolarHBondContact NH2-OD2 3.47Å; D328-D330 VanDerWaalsContact C-N 3.28Å; D328-D330 PolarHBondContact O-N 3.48Å; D328-D330 PolarHBondContact OD1-N 3.26Å; D328-D330 VanDerWaalsContact OD1-N 3.15Å; D330-S332 VanDerWaalsContact C-N 3.33Å; D330-E333 PolarHBondContact O-N 2.9Å; D330-D334 WeakPolarHBondContact O-CB 3.39Å; D330-D334 PolarHBondContact O-N 2.78Å
331	I	94.5	Very high	93.8	Very high	0 Å²	0	75.8 Å²	75.8	0%	0	36%	0.361	C	S	.	.	H	α-helix	trans	-61.9	-46.5	175.1	-66.6	-179.7	0	0	0	109.7	E279 R283 L286 Y326 D328 E329 E333 D334 I335	E279-I331 HydrophobicContact CB-CD1 4.48Å; R283-I331 HydrophobicContact CB-CD1 4Å; R283-I331 HydrophobicContact CB-CG1 3.86Å; R283-I331 HydrophobicContact CG-CG1 4.01Å; L286-I331 HydrophobicContact CD1-CG2 3.91Å; Y326-I331 HydrophobicContact CD1-CD1 4.13Å; Y326-I331 HydrophobicContact CD1-CG2 4.21Å; Y326-I331 HydrophobicContact CD2-CG2 3.77Å; Y326-I331 HydrophobicContact CE1-CG2 4.45Å; Y326-I331 HydrophobicContact CE2-CG2 4.03Å; Y326-I331 HydrophobicContact CG-CB 4.48Å; Y326-I331 HydrophobicContact CG-CG2 3.85Å; D328-I331 HydrophobicContact CB-CB 4.33Å; D328-I331 HydrophobicContact CB-CD1 3.87Å; D328-I331 HydrophobicContact CB-CG1 3.98Å; D328-I331 PolarHBondContact O-N 3.21Å; E329-I331 VanDerWaalsContact C-N 3.32Å; E329-I331 PolarHBondContact O-N 2.96Å; I331-E333 VanDerWaalsContact C-N 3.35Å; I331-E333 PolarHBondContact O-N 2.99Å; I331-D334 PolarHBondContact O-N 3.28Å; I331-I335 HydrophobicContact CG2-CD1 3.7Å; I331-I335 HydrophobicContact CG2-CG1 4.39Å; I331-I335 WeakPolarHBondContact O-CB 3.49Å; I331-I335 VanDerWaalsContact O-CG1 3.24Å; I331-I335 WeakPolarHBondContact O-CG1 3.18Å; I331-I335 PolarHBondContact O-N 3.45Å
332	S	95.1	Very high	93.7	Very high	39 Å²	39	74.8 Å²	74.8	27%	0.273	36%	0.356	S	S	.	.	H	α-helix	trans	-64.9	-38.9	-178.7	-62.7	0	0	0	0	112.1	D328 E329 D330 K336	D328-S332 PolarHBondContact O-N 3.42Å; E329-S332 WeakPolarHBondContact O-CB 3.48Å; E329-S332 PolarHBondContact O-N 3.42Å; E329-S332 VanDerWaalsContact O-N 3.13Å; D330-S332 VanDerWaalsContact C-N 3.33Å; S332-K336 VanDerWaalsContact O-CG 3.32Å; S332-K336 WeakPolarHBondContact O-CG 3.07Å; S332-K336 PolarHBondContact O-N 3.16Å
333	E	96.4	Very high	93.3	Very high	105 Å²	105	71 Å²	71	49%	0.491	35%	0.346	S	S	.	.	H	α-helix	trans	-67.7	-45.3	175.3	-72.5	-169.6	178.5	0	0	112.3	E329 D330 I331 I335 K336 F337	E329-E333 WeakPolarHBondContact O-CG 3.44Å; E329-E333 PolarHBondContact O-N 3.23Å; D330-E333 PolarHBondContact O-N 2.9Å; I331-E333 VanDerWaalsContact C-N 3.35Å; I331-E333 PolarHBondContact O-N 2.99Å; E333-I335 PolarHBondContact O-N 3.35Å; E333-K336 PolarHBondContact O-N 2.92Å; E333-F337 WeakPolarHBondContact O-CB 3.16Å; E333-F337 PolarHBondContact O-N 2.62Å
334	D	97.7	Very high	93.1	Very high	11 Å²	11	67.8 Å²	67.8	6%	0.059	33%	0.33	C	S	.	.	H	α-helix	trans	-65.4	-39.2	179.9	-75.8	-13.6	0	0	0	111.6	L286 A287 R290 D330 I331 F337 L338	L286-D334 HydrophobicContact CB-CB 3.94Å; A287-D334 WeakPolarHBondContact CA-OD2 3.38Å; A287-D334 PolarHBondContact N-OD2 3.1Å; R290-D334 WeakPolarHBondContact CD-OD1 3.42Å; R290-D334 IonicContact CZ-OD1 3.92Å; R290-D334 IonicContact NE-OD1 3.28Å; R290-D334 IonicContact NH1-OD1 3.45Å; R290-D334 PolarHBondContact NH1-OD1 3.32Å; D330-D334 WeakPolarHBondContact O-CB 3.39Å; D330-D334 PolarHBondContact O-N 2.78Å; I331-D334 PolarHBondContact O-N 3.28Å; D334-F337 PolarHBondContact O-N 3.28Å; D334-L338 WeakPolarHBondContact O-CB 3.3Å; D334-L338 WeakPolarHBondContact O-CG 3.22Å; D334-L338 PolarHBondContact O-N 2.94Å
335	I	96.9	Very high	92.9	Very high	3 Å²	3	64 Å²	64	2%	0.015	32%	0.317	C	S	.	.	H	α-helix	trans	-59.2	-50.6	174.4	-71.4	167.6	0	0	0	110.4	L286 L318 L321 E322 Y326 I331 E333 F337 L338 L339	L286-I335 HydrophobicContact CD1-CD1 4.31Å; L286-I335 HydrophobicContact CD1-CG1 3.83Å; L286-I335 HydrophobicContact CD2-CG1 4.49Å; L318-I335 HydrophobicContact CD2-CG1 4.22Å; L321-I335 HydrophobicContact CB-CD1 3.78Å; E322-I335 HydrophobicContact CB-CG2 3.95Å; E322-I335 HydrophobicContact CG-CG2 4.43Å; Y326-I335 HydrophobicContact CD2-CD1 4.44Å; Y326-I335 HydrophobicContact CE2-CD1 4.12Å; I331-I335 HydrophobicContact CG2-CD1 3.7Å; I331-I335 HydrophobicContact CG2-CG1 4.39Å; I331-I335 WeakPolarHBondContact O-CB 3.49Å; I331-I335 VanDerWaalsContact O-CG1 3.24Å; I331-I335 WeakPolarHBondContact O-CG1 3.18Å; I331-I335 PolarHBondContact O-N 3.45Å; E333-I335 PolarHBondContact O-N 3.35Å; I335-F337 PolarHBondContact O-N 2.89Å; I335-L338 PolarHBondContact O-N 3.43Å; I335-L339 HydrophobicContact CG2-CD1 3.75Å; I335-L339 HydrophobicContact CG2-CG 4.34Å; I335-L339 WeakPolarHBondContact O-CB 3.41Å; I335-L339 WeakPolarHBondContact O-CG 3.4Å; I335-L339 PolarHBondContact O-N 3.3Å
336	K	96.4	Very high	92.5	Very high	132 Å²	132	57.3 Å²	57.3	57%	0.574	29%	0.293	S	S	*	.	H	α-helix	trans	-60.4	-46.3	179.9	-73	172	-176	172.4	0	111.8	S332 E333 L338 L339 E340	S332-K336 VanDerWaalsContact O-CG 3.32Å; S332-K336 WeakPolarHBondContact O-CG 3.07Å; S332-K336 PolarHBondContact O-N 3.16Å; E333-K336 PolarHBondContact O-N 2.92Å; K336-L338 VanDerWaalsContact C-N 3.35Å; K336-L338 PolarHBondContact O-N 3.14Å; K336-L339 PolarHBondContact O-N 2.81Å; K336-E340 PolarHBondContact O-N 3.03Å
337	F	97.7	Very high	91.9	Very high	39 Å²	39	63.8 Å²	63.8	17%	0.171	32%	0.324	C	S	.	.	H	α-helix	trans	-58.7	-46.7	177.6	175.7	-90	0	0	0	111.7	R290 L293 E294 E333 D334 I335 E340 K341	R290-F337 HydrophobicContact CB-CD1 4.17Å; R290-F337 HydrophobicContact CB-CE1 4.27Å; R290-F337 HydrophobicContact CG-CD1 3.71Å; R290-F337 HydrophobicContact CG-CE1 3.69Å; R290-F337 HydrophobicContact CG-CG 4.42Å; R290-F337 HydrophobicContact CG-CZ 4.36Å; L293-F337 HydrophobicContact CB-CE1 4.45Å; E294-F337 HydrophobicContact CB-CZ 4.09Å; E294-F337 HydrophobicContact CG-CZ 4.3Å; E333-F337 WeakPolarHBondContact O-CB 3.16Å; E333-F337 PolarHBondContact O-N 2.62Å; D334-F337 PolarHBondContact O-N 3.28Å; I335-F337 PolarHBondContact O-N 2.89Å; F337-E340 PolarHBondContact O-N 3.14Å; F337-K341 HydrophobicContact CD1-CG 4.39Å; F337-K341 HydrophobicContact CD2-CG 4.44Å; F337-K341 HydrophobicContact CE1-CG 3.97Å; F337-K341 HydrophobicContact CE2-CG 4.05Å; F337-K341 HydrophobicContact CZ-CD 4.46Å; F337-K341 HydrophobicContact CZ-CG 3.8Å; F337-K341 WeakPolarHBondContact O-CG 3.14Å; F337-K341 PolarHBondContact O-N 3.24Å
338	L	97.4	Very high	91	Very high	0 Å²	0	61.5 Å²	61.5	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-68	-41.4	-178.9	-69.9	170.7	0	0	0	111.9	L286 F289 L293 L318 D334 I335 K336 E340 K341 L342	L286-L338 HydrophobicContact CB-CD1 4.33Å; L286-L338 HydrophobicContact CD2-CD1 3.79Å; F289-L338 HydrophobicContact CB-CD1 4.01Å; F289-L338 HydrophobicContact CB-CD2 3.86Å; L293-L338 HydrophobicContact CD1-CD2 3.86Å; L318-L338 HydrophobicContact CD1-CB 3.54Å; L318-L338 HydrophobicContact CD1-CD1 4.44Å; L318-L338 HydrophobicContact CD2-CB 4.3Å; L318-L338 HydrophobicContact CD2-CD1 4.03Å; D334-L338 WeakPolarHBondContact O-CB 3.3Å; D334-L338 WeakPolarHBondContact O-CG 3.22Å; D334-L338 PolarHBondContact O-N 2.94Å; I335-L338 PolarHBondContact O-N 3.43Å; K336-L338 VanDerWaalsContact C-N 3.35Å; K336-L338 PolarHBondContact O-N 3.14Å; L338-E340 PolarHBondContact O-N 2.96Å; L338-K341 PolarHBondContact O-N 3.4Å; L338-L342 WeakPolarHBondContact O-CB 3.4Å; L338-L342 VanDerWaalsContact O-CG 3.24Å; L338-L342 WeakPolarHBondContact O-CG 3.21Å; L338-L342 PolarHBondContact O-N 2.92Å
339	L	95.9	Very high	90.1	Very high	30 Å²	30	61.7 Å²	61.7	16%	0.157	31%	0.313	C	S	.	.	H	α-helix	trans	-59.3	-45.5	175.4	-77.1	171.1	0	0	0	111.6	L315 L318 E319 E322 I335 K336 G343	L315-L339 HydrophobicContact CD2-CD2 4.24Å; L318-L339 HydrophobicContact CB-CD2 3.62Å; L318-L339 HydrophobicContact CB-CG 3.91Å; L318-L339 HydrophobicContact CD1-CD2 4.36Å; L318-L339 HydrophobicContact CD1-CG 4.43Å; E319-L339 HydrophobicContact CG-CD2 4.02Å; E322-L339 HydrophobicContact CB-CD1 4.36Å; E322-L339 WeakPolarHBondContact OE2-CD1 3.37Å; I335-L339 HydrophobicContact CG2-CD1 3.75Å; I335-L339 HydrophobicContact CG2-CG 4.34Å; I335-L339 WeakPolarHBondContact O-CB 3.41Å; I335-L339 WeakPolarHBondContact O-CG 3.4Å; I335-L339 PolarHBondContact O-N 3.3Å; K336-L339 PolarHBondContact O-N 2.81Å; L339-G343 WeakPolarHBondContact O-CA 3.47Å; L339-G343 PolarHBondContact O-N 3.31Å
340	E	94.3	Very high	89.4	Confident	111 Å²	111	56.8 Å²	56.8	52%	0.519	30%	0.295	S	S	.	.	H	α-helix	trans	-61.2	-54.6	176.9	-173.3	-166.7	129.5	0	0	111.3	K336 F337 L338 L342 G343 E344	K336-E340 PolarHBondContact O-N 3.03Å; F337-E340 PolarHBondContact O-N 3.14Å; L338-E340 PolarHBondContact O-N 2.96Å; E340-L342 PolarHBondContact O-N 3Å; E340-G343 PolarHBondContact O-N 3.37Å; E340-E344 WeakPolarHBondContact O-CG 3.26Å; E340-E344 PolarHBondContact O-N 3.16Å
341	K	92.9	Very high	89	Confident	58 Å²	58	56.9 Å²	56.9	25%	0.252	30%	0.301	S	S	.	.	H	α-helix	trans	-68.8	-38.3	-173.5	-67.4	-68.9	148.1	-123.6	0	113.3	L293 F337 L338 E344 S345	L293-K341 HydrophobicContact CD1-CB 4.17Å; F337-K341 HydrophobicContact CD1-CG 4.39Å; F337-K341 HydrophobicContact CD2-CG 4.44Å; F337-K341 HydrophobicContact CE1-CG 3.97Å; F337-K341 HydrophobicContact CE2-CG 4.05Å; F337-K341 HydrophobicContact CZ-CD 4.46Å; F337-K341 HydrophobicContact CZ-CG 3.8Å; F337-K341 WeakPolarHBondContact O-CG 3.14Å; F337-K341 PolarHBondContact O-N 3.24Å; L338-K341 PolarHBondContact O-N 3.4Å; K341-E344 VanDerWaalsContact NZ-CD 3.33Å; K341-E344 IonicContact NZ-OE1 3.14Å; K341-E344 PolarHBondContact NZ-OE1 3.43Å; K341-E344 VanDerWaalsContact NZ-OE1 3.14Å; K341-E344 IonicContact NZ-OE2 2.79Å; K341-E344 PolarHBondContact NZ-OE2 3.44Å; K341-S345 PolarHBondContact O-N 3.29Å; K341-S345 PolarHBondContact O-OG 3.33Å
342	L	91.4	Very high	88.7	Confident	0 Å²	0	57.4 Å²	57.4	0%	0	30%	0.303	C	S	.	.	H	α-helix	trans	-72.6	-35.9	175.2	-65	179.1	0	0	0	110.8	L293 A306 M309 I310 V314 L315 L318 L338 E340 S345 V346	L293-L342 HydrophobicContact CD1-CD2 4.02Å; L293-L342 HydrophobicContact CD1-CG 4.39Å; A306-L342 HydrophobicContact CB-CD2 3.88Å; M309-L342 HydrophobicContact CB-CD1 4.06Å; M309-L342 HydrophobicContact CB-CD2 3.95Å; M309-L342 HydrophobicContact SD-CD1 4.29Å; M309-L342 HydrophobicContact SD-CD2 4.02Å; I310-L342 HydrophobicContact CG1-CD2 4.39Å; V314-L342 HydrophobicContact CG1-CD1 4.31Å; L315-L342 HydrophobicContact CD1-CB 4.25Å; L315-L342 HydrophobicContact CD2-CB 3.42Å; L315-L342 VanDerWaalsContact CD2-CB 3.42Å; L315-L342 HydrophobicContact CD2-CD1 4.12Å; L315-L342 HydrophobicContact CD2-CG 4.43Å; L315-L342 HydrophobicContact CG-CB 3.85Å; L315-L342 HydrophobicContact CG-CD1 4.18Å; L318-L342 HydrophobicContact CD1-CD1 3.95Å; L338-L342 WeakPolarHBondContact O-CB 3.4Å; L338-L342 VanDerWaalsContact O-CG 3.24Å; L338-L342 WeakPolarHBondContact O-CG 3.21Å; L338-L342 PolarHBondContact O-N 2.92Å; E340-L342 PolarHBondContact O-N 3Å; L342-S345 PolarHBondContact O-N 3.45Å; L342-V346 WeakPolarHBondContact O-CG2 3.31Å; L342-V346 PolarHBondContact O-N 3.42Å
343	G	86.8	Confident	88.1	Confident	27 Å²	27	58.5 Å²	58.5	28%	0.278	31%	0.306	S	S	.	.	H	α-helix	trans	-61.1	-44.8	174	0	0	0	0	0	113.1	L339 E340 S345 V346 Q347	L339-G343 WeakPolarHBondContact O-CA 3.47Å; L339-G343 PolarHBondContact O-N 3.31Å; E340-G343 PolarHBondContact O-N 3.37Å; G343-S345 VanDerWaalsContact C-N 3.32Å; G343-S345 PolarHBondContact O-N 3.15Å; G343-V346 PolarHBondContact O-N 3.19Å; G343-Q347 PolarHBondContact O-N 3.47Å
344	E	86.9	Confident	87.5	Confident	90 Å²	90	56.2 Å²	56.2	42%	0.421	30%	0.296	S	S	.	.	H	α-helix	trans	-57.5	-45.3	171.1	-72	171.9	170.3	0	0	111.1	E340 K341 V346 Q347 D348	E340-E344 WeakPolarHBondContact O-CG 3.26Å; E340-E344 PolarHBondContact O-N 3.16Å; K341-E344 VanDerWaalsContact NZ-CD 3.33Å; K341-E344 IonicContact NZ-OE1 3.14Å; K341-E344 PolarHBondContact NZ-OE1 3.43Å; K341-E344 VanDerWaalsContact NZ-OE1 3.14Å; K341-E344 IonicContact NZ-OE2 2.79Å; K341-E344 PolarHBondContact NZ-OE2 3.44Å; E344-V346 VanDerWaalsContact C-N 3.33Å; E344-V346 PolarHBondContact O-N 3.44Å; E344-Q347 PolarHBondContact O-N 2.93Å; E344-D348 PolarHBondContact O-N 3.45Å
345	S	84.1	Confident	87.2	Confident	33 Å²	33	55.7 Å²	55.7	23%	0.231	29%	0.293	C	S	.	.	H	α-helix	trans	-66.7	-31.6	-178.4	-58.2	0	0	0	0	113.1	K341 L342 G343 D348 L349	K341-S345 PolarHBondContact O-N 3.29Å; K341-S345 PolarHBondContact O-OG 3.33Å; L342-S345 PolarHBondContact O-N 3.45Å; G343-S345 VanDerWaalsContact C-N 3.32Å; G343-S345 PolarHBondContact O-N 3.15Å; S345-D348 PolarHBondContact O-N 2.96Å; S345-L349 WeakPolarHBondContact O-CB 3.44Å; S345-L349 PolarHBondContact O-N 2.96Å; S345-L349 VanDerWaalsContact O-N 3.15Å
346	V	80.3	Confident	86.8	Confident	67 Å²	67	56.6 Å²	56.6	41%	0.406	30%	0.299	S	S	.	.	H	α-helix	trans	-66.1	-37.7	174.5	168	0	0	0	0	111.5	I310 L315 L342 G343 E344 D348 L349	I310-V346 HydrophobicContact CD1-CG2 3.59Å; I310-V346 HydrophobicContact CG1-CG2 3.93Å; I310-V346 HydrophobicContact CG2-CG2 4.21Å; L315-V346 HydrophobicContact CD1-CG2 3.48Å; L315-V346 VanDerWaalsContact CD1-CG2 3.48Å; L342-V346 WeakPolarHBondContact O-CG2 3.31Å; L342-V346 PolarHBondContact O-N 3.42Å; G343-V346 PolarHBondContact O-N 3.19Å; E344-V346 VanDerWaalsContact C-N 3.33Å; E344-V346 PolarHBondContact O-N 3.44Å; V346-D348 VanDerWaalsContact C-N 3.27Å; V346-D348 PolarHBondContact O-N 3.22Å; V346-L349 WeakPolarHBondContact O-CB 3.45Å; V346-L349 PolarHBondContact O-N 3.41Å
347	Q	75.8	Confident	86.1	Confident	168 Å²	168	50.9 Å²	50.9	79%	0.785	28%	0.276	S	S	*	.	H	α-helix	trans	-67.6	-32.2	178.8	-65.8	-179.1	6.7	0	0	112	G343 E344	G343-Q347 PolarHBondContact O-N 3.47Å; E344-Q347 PolarHBondContact O-N 2.93Å
348	D	72.3	Confident	85.7	Confident	121 Å²	121	49.5 Å²	49.5	65%	0.647	27%	0.27	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.7	-5.3	179.2	-74.8	-13.2	0	0	0	113.7	E344 S345 V346 S350	E344-D348 PolarHBondContact O-N 3.45Å; S345-D348 PolarHBondContact O-N 2.96Å; V346-D348 VanDerWaalsContact C-N 3.27Å; V346-D348 PolarHBondContact O-N 3.22Å; D348-S350 PolarHBondContact O-N 3.26Å
349	L	73.3	Confident	85.3	Confident	43 Å²	43	49.5 Å²	49.5	23%	0.225	27%	0.27	C	S	.	.			trans	-76.4	115.5	-173.7	179.8	48.5	0	0	0	111.7	L307 S345 V346 D353 E354	L307-L349 HydrophobicContact CD1-CD1 4.2Å; L307-L349 HydrophobicContact CD2-CB 4.45Å; L307-L349 HydrophobicContact CD2-CD1 3.28Å; L307-L349 HydrophobicContact CD2-CD2 3.74Å; L307-L349 HydrophobicContact CD2-CG 3.99Å; L307-L349 HydrophobicContact CG-CD1 4.36Å; S345-L349 WeakPolarHBondContact O-CB 3.44Å; S345-L349 PolarHBondContact O-N 2.96Å; S345-L349 VanDerWaalsContact O-N 3.15Å; V346-L349 WeakPolarHBondContact O-CB 3.45Å; V346-L349 PolarHBondContact O-N 3.41Å; L349-D353 HydrophobicContact CD1-CB 3.63Å; L349-E354 HydrophobicContact CD1-CB 4.35Å; L349-E354 HydrophobicContact CD2-CB 4.31Å; L349-E354 HydrophobicContact CG-CB 4.43Å
350	S	79.1	Confident	84.8	Confident	47 Å²	47	51.3 Å²	51.3	33%	0.329	28%	0.277	S	S	.	.			trans	-77.6	150.6	168.7	84.9	0	0	0	0	111.2	D348 F352 D353 E354	D348-S350 PolarHBondContact O-N 3.26Å; S350-F352 PolarHBondContact O-N 3.32Å; S350-F352 PolarHBondContact OG-N 3.47Å; S350-D353 WeakPolarHBondContact CB-OD2 3.37Å; S350-D353 PolarHBondContact N-OD2 3.36Å; S350-D353 PolarHBondContact O-N 3.15Å; S350-D353 PolarHBondContact OG-N 3.27Å; S350-D353 PolarHBondContact OG-OD2 2.9Å; S350-E354 PolarHBondContact O-N 3.24Å
351	S	84	Confident	84.2	Confident	70 Å²	70	46.8 Å²	46.8	49%	0.49	26%	0.257	S	S	.	.	H	α-helix	trans	-56.2	-23.5	174.2	-56.2	0	0	0	0	113.3	Y355 V369 F375	S351-Y355 PolarHBondContact O-N 3.07Å; S351-V369 WeakPolarHBondContact O-CG1 3.46Å; S351-F375 VanDerWaalsContact O-CE2 3.27Å; S351-F375 WeakPolarHBondContact O-CE2 3.4Å
352	F	87.1	Confident	83.9	Confident	11 Å²	11	45.1 Å²	45.1	5%	0.048	26%	0.257	C	S	.	.	H	α-helix	trans	-78.7	-36.1	176.2	-172.7	-101.7	0	0	0	113.5	S350 E354 Y355 S356 F375 N379 R382 L383 L390	S350-F352 PolarHBondContact O-N 3.32Å; S350-F352 PolarHBondContact OG-N 3.47Å; F352-E354 VanDerWaalsContact C-N 3.29Å; F352-Y355 PolarHBondContact O-N 3.48Å; F352-S356 WeakPolarHBondContact O-CB 3.47Å; F352-S356 PolarHBondContact O-N 3.22Å; F352-F375 HydrophobicContact CB-CE2 4.41Å; F352-F375 HydrophobicContact CD2-CE2 4.29Å; F352-F375 HydrophobicContact CD2-CZ 4.15Å; F352-N379 HydrophobicContact CD2-CB 3.59Å; F352-N379 HydrophobicContact CE2-CB 4.04Å; F352-R382 VanDerWaalsContact CB-NH1 3.31Å; F352-R382 VanDerWaalsContact CD1-NH1 3.31Å; F352-R382 HydrophobicContact CD2-CB 4.49Å; F352-R382 HydrophobicContact CE1-CB 4.25Å; F352-R382 HydrophobicContact CE2-CB 3.7Å; F352-R382 VanDerWaalsContact CG-NH1 3.26Å; F352-R382 HydrophobicContact CZ-CB 3.53Å; F352-L383 HydrophobicContact CE2-CD1 3.87Å; F352-L390 HydrophobicContact CE1-CD1 4.4Å; F352-L390 HydrophobicContact CZ-CD1 3.84Å
353	D	84.1	Confident	83.6	Confident	62 Å²	62	49.3 Å²	49.3	33%	0.332	27%	0.273	S	S	.	.	H	α-helix	trans	-71.8	-32.3	179.1	-47.3	-51.5	0	0	0	110.3	L307 L349 S350 S356 S357	L307-D353 HydrophobicContact CD1-CB 3.86Å; L349-D353 HydrophobicContact CD1-CB 3.63Å; S350-D353 WeakPolarHBondContact CB-OD2 3.37Å; S350-D353 PolarHBondContact N-OD2 3.36Å; S350-D353 PolarHBondContact O-N 3.15Å; S350-D353 PolarHBondContact OG-N 3.27Å; S350-D353 PolarHBondContact OG-OD2 2.9Å; D353-S356 PolarHBondContact O-N 3.49Å; D353-S357 VanDerWaalsContact O-CB 3.29Å; D353-S357 WeakPolarHBondContact O-CB 3.41Å; D353-S357 PolarHBondContact O-N 3.2Å
354	E	84	Confident	83.8	Confident	58 Å²	58	48.1 Å²	48.1	27%	0.271	26%	0.26	S	S	.	.	H	α-helix	trans	-56.9	-55	167.7	-176.2	178.3	-169.4	0	0	110.4	Q311 L349 S350 F352 S356 S357 E358 V369	Q311-E354 PolarHBondContact NE2-O 3.44Å; L349-E354 HydrophobicContact CD1-CB 4.35Å; L349-E354 HydrophobicContact CD2-CB 4.31Å; L349-E354 HydrophobicContact CG-CB 4.43Å; S350-E354 PolarHBondContact O-N 3.24Å; F352-E354 VanDerWaalsContact C-N 3.29Å; E354-S356 PolarHBondContact O-N 2.92Å; E354-S357 PolarHBondContact O-N 2.92Å; E354-S357 VanDerWaalsContact O-N 3.17Å; E354-E358 PolarHBondContact O-N 3.14Å; E354-V369 HydrophobicContact CB-CG1 4.19Å; E354-V369 HydrophobicContact CG-CG1 4.13Å; E354-V369 HydrophobicContact CG-CG2 4.35Å; E354-V369 WeakPolarHBondContact OE2-CG1 3.49Å
355	Y	90	Very high	83.8	Confident	0 Å²	0	47.8 Å²	47.8	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-55.7	-48	177	-177	-97.3	0	0	0	113.5	S351 F352 S357 E358 L359 V369 H370 F375 W376 L383 D413	S351-Y355 PolarHBondContact O-N 3.07Å; F352-Y355 PolarHBondContact O-N 3.48Å; Y355-S357 VanDerWaalsContact C-N 3.3Å; Y355-S357 PolarHBondContact O-N 3.39Å; Y355-E358 PolarHBondContact O-N 3.02Å; Y355-L359 HydrophobicContact CD1-CD1 3.96Å; Y355-L359 HydrophobicContact CE1-CD1 3.28Å; Y355-L359 HydrophobicContact CE1-CG 4.17Å; Y355-L359 PolarHBondContact O-N 3.13Å; Y355-V369 HydrophobicContact CD2-CB 4.39Å; Y355-V369 HydrophobicContact CD2-CG2 4.1Å; Y355-H370 AromaticContact CD2-CE1 3.57Å; Y355-H370 AromaticContact CD2-ND1 3.94Å; Y355-H370 AromaticContact CE2-CE1 3.33Å; Y355-H370 WeakPolarHBondContact CE2-CE1 3.44Å; Y355-H370 AromaticContact CE2-ND1 3.53Å; Y355-F375 VanDerWaalsContact CB-CZ 3.48Å; Y355-F375 HydrophobicContact CD1-CZ 4.07Å; Y355-F375 AromaticContact CD2-CE1 3.89Å; Y355-F375 HydrophobicContact CD2-CE1 3.89Å; Y355-F375 AromaticContact CD2-CZ 3.86Å; Y355-F375 HydrophobicContact CD2-CZ 3.86Å; Y355-F375 HydrophobicContact CE2-CE1 4.36Å; Y355-F375 HydrophobicContact CG-CE1 4Å; Y355-F375 AromaticContact CG-CZ 3.52Å; Y355-F375 HydrophobicContact CG-CZ 3.52Å; Y355-W376 AromaticContact CE2-CH2 3.87Å; Y355-W376 HydrophobicContact CE2-CH2 3.87Å; Y355-W376 AromaticContact CE2-CZ2 3.91Å; Y355-W376 HydrophobicContact CE2-CZ2 3.91Å; Y355-W376 AromaticContact CZ-CH2 3.73Å; Y355-W376 WeakPolarHBondContact OH-CH2 3.48Å; Y355-L383 HydrophobicContact CE1-CD1 4.16Å; Y355-L383 HydrophobicContact CE1-CD2 3.87Å; Y355-L383 HydrophobicContact CE1-CG 4.14Å; Y355-D413 WeakPolarHBondContact CE2-OD2 3.48Å; Y355-D413 PolarHBondContact OH-OD2 2.95Å
356	S	88.9	Confident	84.1	Confident	21 Å²	21	49.7 Å²	49.7	15%	0.147	26%	0.261	C	S	.	.	H	α-helix	trans	-61.1	-39.2	179.4	172.4	0	0	0	0	112	F352 D353 E354 K360	F352-S356 WeakPolarHBondContact O-CB 3.47Å; F352-S356 PolarHBondContact O-N 3.22Å; D353-S356 PolarHBondContact O-N 3.49Å; E354-S356 PolarHBondContact O-N 2.92Å; S356-K360 WeakPolarHBondContact O-CG 3.06Å; S356-K360 PolarHBondContact O-N 3.36Å; S356-K360 VanDerWaalsContact O-N 3.15Å
357	S	82.5	Confident	84.4	Confident	12 Å²	12	47.3 Å²	47.3	8%	0.084	25%	0.247	C	C	.	.	H	α-helix	trans	-73.4	-36	179.6	-179.1	0	0	0	0	111.9	Q311 D353 E354 Y355 L359 K360 S361	Q311-S357 VanDerWaalsContact CD-OG 3.24Å; Q311-S357 VanDerWaalsContact NE2-CB 3.27Å; Q311-S357 PolarHBondContact NE2-OG 3Å; Q311-S357 VanDerWaalsContact OE1-CB 3.29Å; Q311-S357 PolarHBondContact OE1-O 3.07Å; Q311-S357 PolarHBondContact OE1-OG 3.24Å; D353-S357 VanDerWaalsContact O-CB 3.29Å; D353-S357 WeakPolarHBondContact O-CB 3.41Å; D353-S357 PolarHBondContact O-N 3.2Å; E354-S357 PolarHBondContact O-N 2.92Å; E354-S357 VanDerWaalsContact O-N 3.17Å; Y355-S357 VanDerWaalsContact C-N 3.3Å; Y355-S357 PolarHBondContact O-N 3.39Å; S357-L359 VanDerWaalsContact C-N 3.34Å; S357-L359 PolarHBondContact O-N 3.46Å; S357-K360 PolarHBondContact O-N 3.38Å; S357-S361 WeakPolarHBondContact O-CB 3.38Å; S357-S361 PolarHBondContact O-N 3.31Å; S357-S361 PolarHBondContact O-OG 3.38Å
358	E	88.3	Confident	84.8	Confident	10 Å²	10	43.9 Å²	43.9	5%	0.047	24%	0.239	C	C	.	.	H	α-helix	trans	-60.8	-46.3	176.3	-71.9	-161.9	-143.2	0	0	109.8	Q311 E354 Y355 S361 G362 R363 L364 E365 S367 H370	Q311-E358 HydrophobicContact CG-CG 4.49Å; E354-E358 PolarHBondContact O-N 3.14Å; Y355-E358 PolarHBondContact O-N 3.02Å; E358-S361 PolarHBondContact O-N 2.89Å; E358-S361 PolarHBondContact O-OG 3.16Å; E358-G362 PolarHBondContact O-N 3.09Å; E358-R363 PolarHBondContact O-N 2.9Å; E358-L364 HydrophobicContact CB-CD2 3.83Å; E358-E365 PolarHBondContact OE2-N 3.24Å; E358-E365 VanDerWaalsContact OE2-N 3.11Å; E358-S367 PolarHBondContact OE1-OG 2.7Å; E358-H370 IonicContact OE1-NE2 3.87Å; E358-H370 IonicContact OE2-CD2 3.61Å; E358-H370 IonicContact OE2-NE2 2.84Å; E358-H370 PolarHBondContact OE2-NE2 2.97Å; E358-H370 VanDerWaalsContact OE2-NE2 3.08Å
359	L	90.2	Very high	85.6	Confident	1 Å²	1	38.2 Å²	38.2	1%	0.005	21%	0.209	C	C	.	.	H	α-helix	trans	-59.6	-50.1	175.7	-77.7	174.6	0	0	0	112.9	Y355 S357 S361 G362 L364 L390 I393 L394 L397	Y355-L359 HydrophobicContact CD1-CD1 3.96Å; Y355-L359 HydrophobicContact CE1-CD1 3.28Å; Y355-L359 HydrophobicContact CE1-CG 4.17Å; Y355-L359 PolarHBondContact O-N 3.13Å; S357-L359 VanDerWaalsContact C-N 3.34Å; S357-L359 PolarHBondContact O-N 3.46Å; L359-S361 VanDerWaalsContact C-N 3.31Å; L359-S361 PolarHBondContact O-N 3.02Å; L359-G362 PolarHBondContact O-N 3.43Å; L359-L364 HydrophobicContact CD2-CD1 4.4Å; L359-L364 HydrophobicContact CD2-CD2 4.07Å; L359-L364 HydrophobicContact CG-CD2 4.38Å; L359-L390 HydrophobicContact CD1-CB 3.93Å; L359-L390 HydrophobicContact CD1-CD2 4.21Å; L359-L390 HydrophobicContact CD1-CG 4.48Å; L359-I393 HydrophobicContact CB-CG2 4.22Å; L359-I393 WeakPolarHBondContact O-CG2 3.25Å; L359-L394 HydrophobicContact CD2-CB 3.84Å; L359-L394 HydrophobicContact CD2-CD1 3.73Å; L359-L394 HydrophobicContact CD2-CG 4.35Å; L359-L397 HydrophobicContact CD2-CD1 4.15Å
360	K	85.3	Confident	86.5	Confident	67 Å²	67	36.1 Å²	36.1	29%	0.291	20%	0.198	S	C	.	.	H	α-helix	trans	-64.5	-35.4	-177.2	-77.5	177.3	171.3	-177.2	0	112.6	E304 S356 S357 G362 I393	E304-K360 IonicContact OE1-NZ 3.45Å; E304-K360 PolarHBondContact OE1-NZ 3Å; S356-K360 WeakPolarHBondContact O-CG 3.06Å; S356-K360 PolarHBondContact O-N 3.36Å; S356-K360 VanDerWaalsContact O-N 3.15Å; S357-K360 PolarHBondContact O-N 3.38Å; K360-G362 VanDerWaalsContact C-N 3.28Å; K360-I393 HydrophobicContact CG-CD1 3.96Å
361	S	81.6	Confident	86.9	Confident	16 Å²	16	40 Å²	40	11%	0.112	21%	0.209	C	C	.	.	H	α-helix	trans	-74.1	-20.8	177.2	72.7	0	0	0	0	113.2	S357 E358 L359 R363	S357-S361 WeakPolarHBondContact O-CB 3.38Å; S357-S361 PolarHBondContact O-N 3.31Å; S357-S361 PolarHBondContact O-OG 3.38Å; E358-S361 PolarHBondContact O-N 2.89Å; E358-S361 PolarHBondContact O-OG 3.16Å; L359-S361 VanDerWaalsContact C-N 3.31Å; L359-S361 PolarHBondContact O-N 3.02Å; S361-R363 PolarHBondContact O-N 2.84Å; S361-R363 PolarHBondContact OG-N 3.43Å
362	G	87	Confident	87.1	Confident	24 Å²	24	39 Å²	39	25%	0.247	20%	0.201	C	C	.	.	T	Hydrogen-bonded Turn	trans	74.1	8.7	-174	0	0	0	0	0	114.2	E358 L359 K360	E358-G362 PolarHBondContact O-N 3.09Å; L359-G362 PolarHBondContact O-N 3.43Å; K360-G362 VanDerWaalsContact C-N 3.28Å
363	R	84.6	Confident	87.1	Confident	88 Å²	88	42.1 Å²	42.1	33%	0.332	22%	0.216	S	C	.	.			trans	-107	86.9	177.4	-66.3	-173	178.5	-166.8	-0.3	109.7	P267 D271 E358 S361	P267-R363 VanDerWaalsContact CB-CZ 3.4Å; P267-R363 PolarHBondContact O-NH2 3.47Å; D271-R363 VanDerWaalsContact CG-NH2 3.32Å; D271-R363 IonicContact OD1-CZ 3.68Å; D271-R363 IonicContact OD1-NH1 2.69Å; D271-R363 PolarHBondContact OD1-NH1 2.97Å; D271-R363 IonicContact OD1-NH2 2.76Å; D271-R363 PolarHBondContact OD1-NH2 3.16Å; D271-R363 IonicContact OD2-CZ 2.72Å; D271-R363 IonicContact OD2-NH1 3.86Å; D271-R363 IonicContact OD2-NH2 2.78Å; D271-R363 PolarHBondContact OD2-NH2 3.33Å; E358-R363 PolarHBondContact O-N 2.9Å; S361-R363 PolarHBondContact O-N 2.84Å; S361-R363 PolarHBondContact OG-N 3.43Å
364	L	90.4	Very high	87.1	Confident	2 Å²	2	45.8 Å²	45.8	1%	0.01	23%	0.229	C	C	.	.			trans	-86.3	125.9	176.5	-58.4	-177.8	0	0	0	110.5	E358 L359 L397 Q405 V406 V409 A410	E358-L364 HydrophobicContact CB-CD2 3.83Å; L359-L364 HydrophobicContact CD2-CD1 4.4Å; L359-L364 HydrophobicContact CD2-CD2 4.07Å; L359-L364 HydrophobicContact CG-CD2 4.38Å; L364-L397 HydrophobicContact CD1-CD1 4Å; L364-L397 HydrophobicContact CG-CD1 4.27Å; L364-Q405 PolarHBondContact O-NE2 2.94Å; L364-V406 HydrophobicContact CB-CG1 4.35Å; L364-V406 HydrophobicContact CB-CG2 4.47Å; L364-V406 HydrophobicContact CD1-CG1 4.09Å; L364-V406 HydrophobicContact CG-CG1 4.18Å; L364-V409 HydrophobicContact CB-CB 3.94Å; L364-V409 HydrophobicContact CB-CG1 3.89Å; L364-V409 HydrophobicContact CB-CG2 4.47Å; L364-V409 HydrophobicContact CD1-CB 4.33Å; L364-V409 HydrophobicContact CD1-CG1 4.18Å; L364-A410 HydrophobicContact CD1-CB 3.88Å
365	E	88	Confident	87.4	Confident	83 Å²	83	43.4 Å²	43.4	39%	0.388	22%	0.218	S	C	.	.			trans	-122	158	171.7	-61.5	-164.6	172.2	0	0	111	K313 E358 S367 H370	K313-E365 IonicContact NZ-OE1 3.57Å; K313-E365 PolarHBondContact NZ-OE1 3.28Å; K313-E365 IonicContact NZ-OE2 2.74Å; K313-E365 PolarHBondContact NZ-OE2 2.58Å; E358-E365 PolarHBondContact OE2-N 3.24Å; E358-E365 VanDerWaalsContact OE2-N 3.11Å; E365-S367 VanDerWaalsContact C-N 3.3Å; E365-S367 PolarHBondContact O-N 2.85Å; E365-H370 PolarHBondContact O-CD2 3.02Å
366	W	90.4	Very high	87.6	Confident	73 Å²	73	43.5 Å²	43.5	28%	0.277	22%	0.218	S	C	.	.			trans	-72.9	81.8	178.2	-81.8	118.3	0	0	0	112.2	H370 K371 V409 H412	W366-H370 HydrophobicContact CE3-CB 4.35Å; W366-K371 HydrophobicContact CE3-CD 4.36Å; W366-K371 HydrophobicContact CE3-CG 3.9Å; W366-K371 HydrophobicContact CZ3-CG 4.29Å; W366-V409 HydrophobicContact CD2-CG2 3.72Å; W366-V409 HydrophobicContact CE3-CG2 4.12Å; W366-V409 HydrophobicContact CG-CG2 4.06Å; W366-V409 HydrophobicContact CH2-CG2 4.45Å; W366-V409 HydrophobicContact CZ2-CG2 4.04Å; W366-V409 HydrophobicContact CZ3-CG2 4.48Å; W366-H412 HydrophobicContact CH2-CB 3.63Å; W366-H412 AromaticContact CH2-CD2 3.86Å; W366-H412 AromaticContact CH2-CG 3.59Å; W366-H412 HydrophobicContact CZ3-CB 4.24Å; W366-H412 AromaticContact CZ3-CG 3.81Å; W366-H412 AromaticContact CZ3-ND1 3.87Å
367	S	85.7	Confident	87.6	Confident	16 Å²	16	50.2 Å²	50.2	11%	0.112	24%	0.24	C	C	.	.			trans	-106.1	169.7	-180	68.2	0	0	0	0	112.5	E358 E365 V369 H370 K371	E358-S367 PolarHBondContact OE1-OG 2.7Å; E365-S367 VanDerWaalsContact C-N 3.3Å; E365-S367 PolarHBondContact O-N 2.85Å; S367-V369 PolarHBondContact O-N 3.32Å; S367-V369 WeakPolarHBondContact OG-CG2 3.38Å; S367-H370 PolarHBondContact O-N 2.76Å; S367-H370 VanDerWaalsContact O-N 3.14Å; S367-H370 PolarHBondContact OG-CD2 2.78Å; S367-H370 VanDerWaalsContact OG-CD2 3.3Å; S367-K371 PolarHBondContact O-N 3.15Å
368	P	83.4	Confident	87.9	Confident	96 Å²	96	55.4 Å²	55.4	62%	0.623	26%	0.264	S	S	*	.	H	α-helix	trans	-56.3	-28.8	176.6	-27	36.6	0	0	0	113.9	H370 K371 S372	P368-H370 VanDerWaalsContact C-N 3.29Å; P368-H370 PolarHBondContact O-N 3.21Å; P368-K371 PolarHBondContact O-N 3.33Å; P368-S372 WeakPolarHBondContact O-CA 3.48Å; P368-S372 WeakPolarHBondContact O-CB 3.32Å; P368-S372 PolarHBondContact O-N 3.44Å
369	V	89.7	Confident	88.1	Confident	2 Å²	2	55.8 Å²	55.8	1%	0.012	27%	0.266	C	S	.	.	H	α-helix	trans	-69	-28.9	179.3	-55.8	0	0	0	0	112.2	S351 E354 Y355 S367 F375	S351-V369 WeakPolarHBondContact O-CG1 3.46Å; E354-V369 HydrophobicContact CB-CG1 4.19Å; E354-V369 HydrophobicContact CG-CG1 4.13Å; E354-V369 HydrophobicContact CG-CG2 4.35Å; E354-V369 WeakPolarHBondContact OE2-CG1 3.49Å; Y355-V369 HydrophobicContact CD2-CB 4.39Å; Y355-V369 HydrophobicContact CD2-CG2 4.1Å; S367-V369 PolarHBondContact O-N 3.32Å; S367-V369 WeakPolarHBondContact OG-CG2 3.38Å; V369-F375 HydrophobicContact CB-CD2 4.27Å; V369-F375 HydrophobicContact CB-CE2 4.2Å; V369-F375 HydrophobicContact CB-CZ 4.38Å; V369-F375 HydrophobicContact CG1-CD2 4.43Å; V369-F375 HydrophobicContact CG1-CE2 4.46Å; V369-F375 WeakPolarHBondContact O-CD1 3.39Å; V369-F375 VanDerWaalsContact O-CE1 3.26Å; V369-F375 WeakPolarHBondContact O-CE1 3.39Å; V369-F375 WeakPolarHBondContact O-CG 3.39Å
370	H	92.5	Very high	88.2	Confident	0 Å²	0	55.8 Å²	55.8	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-82.9	-33.8	173.9	-66	-70.9	0	0	0	112.6	Y355 E358 E365 W366 S367 P368 W376 V409 H412 D413	Y355-H370 AromaticContact CD2-CE1 3.57Å; Y355-H370 AromaticContact CD2-ND1 3.94Å; Y355-H370 AromaticContact CE2-CE1 3.33Å; Y355-H370 WeakPolarHBondContact CE2-CE1 3.44Å; Y355-H370 AromaticContact CE2-ND1 3.53Å; E358-H370 IonicContact OE1-NE2 3.87Å; E358-H370 IonicContact OE2-CD2 3.61Å; E358-H370 IonicContact OE2-NE2 2.84Å; E358-H370 PolarHBondContact OE2-NE2 2.97Å; E358-H370 VanDerWaalsContact OE2-NE2 3.08Å; E365-H370 PolarHBondContact O-CD2 3.02Å; W366-H370 HydrophobicContact CE3-CB 4.35Å; S367-H370 PolarHBondContact O-N 2.76Å; S367-H370 VanDerWaalsContact O-N 3.14Å; S367-H370 PolarHBondContact OG-CD2 2.78Å; S367-H370 VanDerWaalsContact OG-CD2 3.3Å; P368-H370 VanDerWaalsContact C-N 3.29Å; P368-H370 PolarHBondContact O-N 3.21Å; H370-W376 PolarHBondContact O-NE1 3.4Å; H370-V409 HydrophobicContact CB-CG1 4.17Å; H370-V409 WeakPolarHBondContact ND1-CG1 3.26Å; H370-H412 PolarHBondContact O-CE1 2.82Å; H370-D413 IonicContact CE1-OD2 3.71Å; H370-D413 PolarHBondContact CE1-OD2 3.48Å; H370-D413 IonicContact CG-OD1 3.01Å; H370-D413 IonicContact ND1-OD1 3.99Å; H370-D413 PolarHBondContact ND1-OD1 3.39Å; H370-D413 IonicContact ND1-OD2 3.62Å; H370-D413 PolarHBondContact ND1-OD2 3.4Å
371	K	87.7	Confident	88.5	Confident	129 Å²	129	56.9 Å²	56.9	56%	0.561	28%	0.278	S	S	*	.	H	α-helix	trans	-94.8	-25.5	-171.7	-67.1	176.5	175.6	167.9	0	115.1	W366 S367 P368 E373	W366-K371 HydrophobicContact CE3-CD 4.36Å; W366-K371 HydrophobicContact CE3-CG 3.9Å; W366-K371 HydrophobicContact CZ3-CG 4.29Å; S367-K371 PolarHBondContact O-N 3.15Å; P368-K371 PolarHBondContact O-N 3.33Å; K371-E373 PolarHBondContact O-N 3.46Å
372	S	88.4	Confident	89	Confident	47 Å²	47	60.1 Å²	60.1	33%	0.329	29%	0.288	S	S	.	.			trans	-76.8	118.7	-170.9	178.2	0	0	0	0	111.6	P368 K374 F375 W376	P368-S372 WeakPolarHBondContact O-CA 3.48Å; P368-S372 WeakPolarHBondContact O-CB 3.32Å; P368-S372 PolarHBondContact O-N 3.44Å; S372-K374 PolarHBondContact O-N 2.98Å; S372-K374 PolarHBondContact OG-N 3.37Å; S372-F375 WeakPolarHBondContact O-CB 3.34Å; S372-F375 PolarHBondContact O-N 3.03Å; S372-F375 VanDerWaalsContact O-N 3.17Å; S372-F375 PolarHBondContact OG-N 3.43Å; S372-W376 VanDerWaalsContact O-CD1 3.28Å; S372-W376 PolarHBondContact O-N 2.85Å
373	E	86.6	Confident	89.3	Confident	78 Å²	78	59 Å²	59	36%	0.364	28%	0.276	S	S	.	.	H	α-helix	trans	-61.6	-33.7	174.1	-165.5	-178.9	169.2	0	0	111.9	K371 F375 W376 R377 R419	K371-E373 PolarHBondContact O-N 3.46Å; E373-F375 VanDerWaalsContact C-N 3.33Å; E373-F375 PolarHBondContact O-N 3.06Å; E373-W376 PolarHBondContact O-N 3.45Å; E373-R377 WeakPolarHBondContact O-CG 3.45Å; E373-R377 PolarHBondContact O-N 3.14Å; E373-R377 IonicContact OE1-CZ 3.32Å; E373-R377 IonicContact OE1-NE 2.75Å; E373-R377 PolarHBondContact OE1-NE 2.9Å; E373-R377 IonicContact OE1-NH2 3.83Å; E373-R377 PolarHBondContact OE1-NH2 3.4Å; E373-R377 IonicContact OE2-NH2 3.09Å; E373-R377 PolarHBondContact OE2-NH2 3.24Å; E373-R419 IonicContact OE1-NH2 3.13Å; E373-R419 PolarHBondContact OE1-NH2 3.44Å; E373-R419 IonicContact OE2-NH2 2.58Å
374	K	83.1	Confident	89.7	Confident	139 Å²	139	56.2 Å²	56.2	60%	0.604	27%	0.268	S	S	*	.	H	α-helix	trans	-61.1	-43.7	176.2	-176.5	-177.8	174.5	-173.4	0	111.1	S372 W376 R377 E378	S372-K374 PolarHBondContact O-N 2.98Å; S372-K374 PolarHBondContact OG-N 3.37Å; K374-W376 PolarHBondContact O-N 3.32Å; K374-R377 PolarHBondContact O-N 3.31Å; K374-E378 WeakPolarHBondContact CE-OE1 3.39Å; K374-E378 WeakPolarHBondContact CG-OE1 3.39Å; K374-E378 WeakPolarHBondContact O-CG 3.34Å; K374-E378 PolarHBondContact O-N 3.43Å; K374-E378 VanDerWaalsContact O-N 3.15Å
375	F	91.6	Very high	89.7	Confident	8 Å²	8	60.7 Å²	60.7	4%	0.035	29%	0.289	C	S	.	.	H	α-helix	trans	-57.2	-50.6	177	170	-92.1	0	0	0	111.1	S351 F352 Y355 V369 S372 E373 E378 N379	S351-F375 VanDerWaalsContact O-CE2 3.27Å; S351-F375 WeakPolarHBondContact O-CE2 3.4Å; F352-F375 HydrophobicContact CB-CE2 4.41Å; F352-F375 HydrophobicContact CD2-CE2 4.29Å; F352-F375 HydrophobicContact CD2-CZ 4.15Å; Y355-F375 VanDerWaalsContact CB-CZ 3.48Å; Y355-F375 HydrophobicContact CD1-CZ 4.07Å; Y355-F375 AromaticContact CD2-CE1 3.89Å; Y355-F375 HydrophobicContact CD2-CE1 3.89Å; Y355-F375 AromaticContact CD2-CZ 3.86Å; Y355-F375 HydrophobicContact CD2-CZ 3.86Å; Y355-F375 HydrophobicContact CE2-CE1 4.36Å; Y355-F375 HydrophobicContact CG-CE1 4Å; Y355-F375 AromaticContact CG-CZ 3.52Å; Y355-F375 HydrophobicContact CG-CZ 3.52Å; V369-F375 HydrophobicContact CB-CD2 4.27Å; V369-F375 HydrophobicContact CB-CE2 4.2Å; V369-F375 HydrophobicContact CB-CZ 4.38Å; V369-F375 HydrophobicContact CG1-CD2 4.43Å; V369-F375 HydrophobicContact CG1-CE2 4.46Å; V369-F375 WeakPolarHBondContact O-CD1 3.39Å; V369-F375 VanDerWaalsContact O-CE1 3.26Å; V369-F375 WeakPolarHBondContact O-CE1 3.39Å; V369-F375 WeakPolarHBondContact O-CG 3.39Å; S372-F375 WeakPolarHBondContact O-CB 3.34Å; S372-F375 PolarHBondContact O-N 3.03Å; S372-F375 VanDerWaalsContact O-N 3.17Å; S372-F375 PolarHBondContact OG-N 3.43Å; E373-F375 VanDerWaalsContact C-N 3.33Å; E373-F375 PolarHBondContact O-N 3.06Å; F375-E378 PolarHBondContact O-N 3.23Å; F375-N379 HydrophobicContact CD2-CB 4.48Å; F375-N379 WeakPolarHBondContact CD2-ND2 3.43Å; F375-N379 HydrophobicContact CE1-CB 4.44Å; F375-N379 HydrophobicContact CE2-CB 4.08Å; F375-N379 HydrophobicContact CZ-CB 4.05Å; F375-N379 WeakPolarHBondContact O-CB 3.12Å; F375-N379 PolarHBondContact O-N 2.92Å; F375-N379 PolarHBondContact O-ND2 3.44Å
376	W	93.4	Very high	89.8	Confident	1 Å²	1	63.8 Å²	63.8	0%	0.004	30%	0.301	C	S	.	.	H	α-helix	trans	-66.9	-38.4	-177.1	-73.9	106.4	0	0	0	113	Y355 H370 S372 E373 K374 E378 A380 L383 D413 E416 H420	Y355-W376 AromaticContact CE2-CH2 3.87Å; Y355-W376 HydrophobicContact CE2-CH2 3.87Å; Y355-W376 AromaticContact CE2-CZ2 3.91Å; Y355-W376 HydrophobicContact CE2-CZ2 3.91Å; Y355-W376 AromaticContact CZ-CH2 3.73Å; Y355-W376 WeakPolarHBondContact OH-CH2 3.48Å; H370-W376 PolarHBondContact O-NE1 3.4Å; S372-W376 VanDerWaalsContact O-CD1 3.28Å; S372-W376 PolarHBondContact O-N 2.85Å; E373-W376 PolarHBondContact O-N 3.45Å; K374-W376 PolarHBondContact O-N 3.32Å; W376-E378 VanDerWaalsContact C-N 3.3Å; W376-E378 PolarHBondContact O-N 3Å; W376-A380 HydrophobicContact CE3-CB 4.41Å; W376-A380 WeakPolarHBondContact O-CB 3.27Å; W376-A380 PolarHBondContact O-N 3.37Å; W376-L383 HydrophobicContact CH2-CD2 4.49Å; W376-L383 HydrophobicContact CZ3-CD2 4.06Å; W376-D413 HydrophobicContact CH2-CB 3.77Å; W376-D413 HydrophobicContact CZ2-CB 3.89Å; W376-D413 WeakPolarHBondContact CZ2-OD1 3.48Å; W376-E416 HydrophobicContact CD2-CB 3.56Å; W376-E416 HydrophobicContact CD2-CG 4.49Å; W376-E416 HydrophobicContact CE3-CB 4.04Å; W376-E416 HydrophobicContact CG-CB 3.86Å; W376-E416 HydrophobicContact CG-CG 4.45Å; W376-E416 HydrophobicContact CH2-CB 4.4Å; W376-E416 HydrophobicContact CZ2-CB 3.99Å; W376-E416 HydrophobicContact CZ3-CB 4.43Å; W376-H420 HydrophobicContact CB-CB 4.4Å
377	R	88.5	Confident	89.8	Confident	162 Å²	162	65.5 Å²	65.5	61%	0.611	32%	0.316	S	S	*	.	H	α-helix	trans	-59.5	-40.9	173.4	-73.7	-179.6	-159.5	174.9	7.2	112.5	E373 K374	E373-R377 WeakPolarHBondContact O-CG 3.45Å; E373-R377 PolarHBondContact O-N 3.14Å; E373-R377 IonicContact OE1-CZ 3.32Å; E373-R377 IonicContact OE1-NE 2.75Å; E373-R377 PolarHBondContact OE1-NE 2.9Å; E373-R377 IonicContact OE1-NH2 3.83Å; E373-R377 PolarHBondContact OE1-NH2 3.4Å; E373-R377 IonicContact OE2-NH2 3.09Å; E373-R377 PolarHBondContact OE2-NH2 3.24Å; K374-R377 PolarHBondContact O-N 3.31Å
378	E	89	Confident	90.2	Very high	122 Å²	122	68.1 Å²	68.1	57%	0.57	32%	0.323	S	S	*	.	H	α-helix	trans	-82.1	-33.3	-175.6	-69.7	172.4	-176.5	0	0	112.4	K374 F375 W376	K374-E378 WeakPolarHBondContact CE-OE1 3.39Å; K374-E378 WeakPolarHBondContact CG-OE1 3.39Å; K374-E378 WeakPolarHBondContact O-CG 3.34Å; K374-E378 PolarHBondContact O-N 3.43Å; K374-E378 VanDerWaalsContact O-N 3.15Å; F375-E378 PolarHBondContact O-N 3.23Å; W376-E378 VanDerWaalsContact C-N 3.3Å; W376-E378 PolarHBondContact O-N 3Å
379	N	92.4	Very high	90.6	Very high	17 Å²	17	67 Å²	67	9%	0.091	31%	0.31	C	S	.	.	H	α-helix	trans	-115.3	-11.7	-166.7	-62.7	-75.2	0	0	0	115.7	F352 F375 V381 R382 L383	F352-N379 HydrophobicContact CD2-CB 3.59Å; F352-N379 HydrophobicContact CE2-CB 4.04Å; F375-N379 HydrophobicContact CD2-CB 4.48Å; F375-N379 WeakPolarHBondContact CD2-ND2 3.43Å; F375-N379 HydrophobicContact CE1-CB 4.44Å; F375-N379 HydrophobicContact CE2-CB 4.08Å; F375-N379 HydrophobicContact CZ-CB 4.05Å; F375-N379 WeakPolarHBondContact O-CB 3.12Å; F375-N379 PolarHBondContact O-N 2.92Å; F375-N379 PolarHBondContact O-ND2 3.44Å; N379-V381 PolarHBondContact O-N 2.59Å; N379-V381 VanDerWaalsContact O-N 3.08Å; N379-R382 WeakPolarHBondContact O-CB 3.4Å; N379-R382 PolarHBondContact O-N 2.88Å; N379-R382 PolarHBondContact OD1-NH1 3Å; N379-L383 WeakPolarHBondContact O-CD1 3.32Å
380	A	92	Very high	90.8	Very high	1 Å²	1	67.5 Å²	67.5	1%	0.008	31%	0.313	C	S	.	.	G	3₁₀ helix	trans	-54.6	-34.8	-177.5	0	0	0	0	0	113.3	W376 R382 L383 Y417 H420	W376-A380 HydrophobicContact CE3-CB 4.41Å; W376-A380 WeakPolarHBondContact O-CB 3.27Å; W376-A380 PolarHBondContact O-N 3.37Å; A380-R382 VanDerWaalsContact C-N 3.32Å; A380-R382 PolarHBondContact O-N 3.34Å; A380-L383 PolarHBondContact O-N 3.14Å; A380-Y417 HydrophobicContact CB-CD2 4.38Å; A380-Y417 VanDerWaalsContact O-CE2 3.28Å; A380-Y417 WeakPolarHBondContact O-CE2 3.35Å; A380-H420 HydrophobicContact CB-CB 3.77Å
381	V	92.4	Very high	90.9	Very high	90 Å²	90	67.6 Å²	67.6	55%	0.545	31%	0.313	S	S	.	.	G	3₁₀ helix	trans	-67.3	-33.4	178.2	-179.4	0	0	0	0	112	N379 L383 N384 Y421	N379-V381 PolarHBondContact O-N 2.59Å; N379-V381 VanDerWaalsContact O-N 3.08Å; V381-L383 PolarHBondContact O-N 2.8Å; V381-N384 VanDerWaalsContact O-CB 3.28Å; V381-N384 WeakPolarHBondContact O-CB 3.05Å; V381-N384 PolarHBondContact O-N 3.07Å; V381-N384 VanDerWaalsContact O-N 3.15Å; V381-N384 PolarHBondContact O-ND2 2.95Å; V381-Y421 HydrophobicContact CG2-CD2 4.1Å; V381-Y421 HydrophobicContact CG2-CE2 4.43Å
382	R	92.5	Very high	91.3	Very high	85 Å²	85	65.4 Å²	65.4	32%	0.321	30%	0.303	S	S	.	.	G	3₁₀ helix	trans	-67.7	-23.2	-178.4	-61	-177.9	64.9	-167.1	-2.7	112.7	F352 N379 A380 N384 E385	F352-R382 VanDerWaalsContact CB-NH1 3.31Å; F352-R382 VanDerWaalsContact CD1-NH1 3.31Å; F352-R382 HydrophobicContact CD2-CB 4.49Å; F352-R382 HydrophobicContact CE1-CB 4.25Å; F352-R382 HydrophobicContact CE2-CB 3.7Å; F352-R382 VanDerWaalsContact CG-NH1 3.26Å; F352-R382 HydrophobicContact CZ-CB 3.53Å; N379-R382 WeakPolarHBondContact O-CB 3.4Å; N379-R382 PolarHBondContact O-N 2.88Å; N379-R382 PolarHBondContact OD1-NH1 3Å; A380-R382 VanDerWaalsContact C-N 3.32Å; A380-R382 PolarHBondContact O-N 3.34Å; R382-N384 PolarHBondContact O-N 2.87Å; R382-E385 WeakPolarHBondContact CB-OE1 3.32Å; R382-E385 WeakPolarHBondContact CG-OE1 3.39Å; R382-E385 IonicContact NE-OE1 3.38Å; R382-E385 VanDerWaalsContact O-CB 3.23Å; R382-E385 WeakPolarHBondContact O-CB 3.38Å; R382-E385 WeakPolarHBondContact O-CG 3.3Å; R382-E385 PolarHBondContact O-N 2.94Å
383	L	92.6	Very high	91.5	Very high	1 Å²	1	65.3 Å²	65.3	1%	0.005	30%	0.299	C	S	.	.	G	3₁₀ helix	trans	-63	-11.8	173.7	-81.7	77	0	0	0	113	F352 Y355 W376 N379 A380 V381 L391 Y417	F352-L383 HydrophobicContact CE2-CD1 3.87Å; Y355-L383 HydrophobicContact CE1-CD1 4.16Å; Y355-L383 HydrophobicContact CE1-CD2 3.87Å; Y355-L383 HydrophobicContact CE1-CG 4.14Å; W376-L383 HydrophobicContact CH2-CD2 4.49Å; W376-L383 HydrophobicContact CZ3-CD2 4.06Å; N379-L383 WeakPolarHBondContact O-CD1 3.32Å; A380-L383 PolarHBondContact O-N 3.14Å; V381-L383 PolarHBondContact O-N 2.8Å; L383-L391 HydrophobicContact CB-CD1 4.4Å; L383-L391 HydrophobicContact CB-CD2 4.17Å; L383-L391 HydrophobicContact CB-CG 4.05Å; L383-L391 HydrophobicContact CD2-CD2 3.68Å; L383-L391 HydrophobicContact CD2-CG 4.37Å; L383-Y417 HydrophobicContact CB-CD2 4.15Å; L383-Y417 HydrophobicContact CB-CE2 4.04Å; L383-Y417 HydrophobicContact CD2-CD2 4.09Å
384	N	92.9	Very high	91.9	Very high	28 Å²	28	61.6 Å²	61.6	15%	0.15	28%	0.281	C	S	.	.	G	3₁₀ helix	trans	-85	-9.5	174.8	-55.2	-42.8	0	0	0	113.8	V381 R382 Y388 Y417	V381-N384 VanDerWaalsContact O-CB 3.28Å; V381-N384 WeakPolarHBondContact O-CB 3.05Å; V381-N384 PolarHBondContact O-N 3.07Å; V381-N384 VanDerWaalsContact O-N 3.15Å; V381-N384 PolarHBondContact O-ND2 2.95Å; R382-N384 PolarHBondContact O-N 2.87Å; N384-Y388 HydrophobicContact CB-CD1 3.99Å; N384-Y388 HydrophobicContact CB-CE1 3.75Å; N384-Y388 PolarHBondContact O-N 3.09Å; N384-Y388 WeakPolarHBondContact OD1-CE1 3.23Å; N384-Y417 PolarHBondContact OD1-OH 2.89Å
385	E	91.4	Very high	92.5	Very high	96 Å²	96	55.6 Å²	55.6	45%	0.449	26%	0.256	S	S	.	.	H	α-helix	trans	-62.8	161.2	178.9	-67.5	169.8	-163.5	0	0	111.4	R382 N387 Y388 E389	R382-E385 WeakPolarHBondContact CB-OE1 3.32Å; R382-E385 WeakPolarHBondContact CG-OE1 3.39Å; R382-E385 IonicContact NE-OE1 3.38Å; R382-E385 VanDerWaalsContact O-CB 3.23Å; R382-E385 WeakPolarHBondContact O-CB 3.38Å; R382-E385 WeakPolarHBondContact O-CG 3.3Å; R382-E385 PolarHBondContact O-N 2.94Å; E385-N387 PolarHBondContact O-N 3.23Å; E385-N387 VanDerWaalsContact O-N 3.12Å; E385-Y388 PolarHBondContact O-N 2.75Å; E385-E389 PolarHBondContact O-N 3.35Å
386	K	89.4	Confident	92.6	Very high	148 Å²	148	60.2 Å²	60.2	64%	0.643	28%	0.276	S	S	*	.	H	α-helix	trans	49.5	41.1	177.7	-60.8	-177.3	178.7	-178.7	0	113.8	E389	K386-E389 HydrophobicContact CB-CB 3.98Å; K386-E389 WeakPolarHBondContact CB-OE2 3.28Å; K386-E389 WeakPolarHBondContact CD-OE2 3.28Å
387	N	90.8	Very high	92.6	Very high	110 Å²	110	61.2 Å²	61.2	59%	0.588	28%	0.282	S	S	*	.	H	α-helix	trans	57.6	50	-178	-172.4	27.2	0	0	0	112.4	E385 E389 K392	E385-N387 PolarHBondContact O-N 3.23Å; E385-N387 VanDerWaalsContact O-N 3.12Å; N387-E389 VanDerWaalsContact C-N 3.27Å; N387-E389 PolarHBondContact O-N 2.91Å; N387-K392 PolarHBondContact ND2-NZ 2.67Å; N387-K392 WeakPolarHBondContact O-CE 3.19Å; N387-K392 PolarHBondContact O-NZ 3.17Å
388	Y	92.9	Very high	92.9	Very high	71 Å²	71	53.6 Å²	53.6	28%	0.278	25%	0.253	S	S	.	.	H	α-helix	trans	60.4	33.6	176.6	-46.8	-82.6	0	0	0	113.3	N384 E385 L390 L391 K392 V427	N384-Y388 HydrophobicContact CB-CD1 3.99Å; N384-Y388 HydrophobicContact CB-CE1 3.75Å; N384-Y388 PolarHBondContact O-N 3.09Å; N384-Y388 WeakPolarHBondContact OD1-CE1 3.23Å; E385-Y388 PolarHBondContact O-N 2.75Å; Y388-L390 PolarHBondContact O-N 2.75Å; Y388-L391 HydrophobicContact CD1-CD1 3.96Å; Y388-L391 PolarHBondContact O-N 3.32Å; Y388-K392 WeakPolarHBondContact O-CG 3.43Å; Y388-K392 PolarHBondContact O-N 2.96Å; Y388-V427 HydrophobicContact CD1-CG1 3.67Å; Y388-V427 HydrophobicContact CE1-CG1 3.74Å; Y388-V427 HydrophobicContact CE1-CG2 4.07Å; Y388-V427 HydrophobicContact CG-CG1 4.32Å
389	E	92.6	Very high	93.1	Very high	71 Å²	71	53.3 Å²	53.3	33%	0.332	25%	0.252	S	S	.	.	H	α-helix	trans	-54.3	-51.7	-176.3	-176.1	-173.7	169.7	0	0	111.8	E385 K386 N387 L391 K392 I393	E385-E389 PolarHBondContact O-N 3.35Å; K386-E389 HydrophobicContact CB-CB 3.98Å; K386-E389 WeakPolarHBondContact CB-OE2 3.28Å; K386-E389 WeakPolarHBondContact CD-OE2 3.28Å; N387-E389 VanDerWaalsContact C-N 3.27Å; N387-E389 PolarHBondContact O-N 2.91Å; E389-L391 PolarHBondContact O-N 3.48Å; E389-K392 WeakPolarHBondContact O-CB 3.35Å; E389-K392 PolarHBondContact O-N 3.39Å; E389-I393 HydrophobicContact CG-CD1 4.22Å; E389-I393 WeakPolarHBondContact O-CG1 3.32Å; E389-I393 PolarHBondContact O-N 3.32Å
390	L	93.8	Very high	93.1	Very high	14 Å²	14	56.4 Å²	56.4	7%	0.073	27%	0.271	C	S	.	.	H	α-helix	trans	-64.2	-38.5	-179.2	-66	-177.6	0	0	0	112.5	F352 L359 Y388 I393 L394	F352-L390 HydrophobicContact CE1-CD1 4.4Å; F352-L390 HydrophobicContact CZ-CD1 3.84Å; L359-L390 HydrophobicContact CD1-CB 3.93Å; L359-L390 HydrophobicContact CD1-CD2 4.21Å; L359-L390 HydrophobicContact CD1-CG 4.48Å; Y388-L390 PolarHBondContact O-N 2.75Å; L390-I393 PolarHBondContact O-N 3.49Å; L390-L394 WeakPolarHBondContact O-CB 3.43Å; L390-L394 PolarHBondContact O-N 2.94Å
391	L	95	Very high	93.1	Very high	1 Å²	1	57.6 Å²	57.6	1%	0.005	28%	0.279	C	S	.	.	H	α-helix	trans	-68.3	-37.1	176	-67.5	173.1	0	0	0	112	L383 Y388 E389 I393 L394 T395 Y417 V427 I428 L431	L383-L391 HydrophobicContact CB-CD1 4.4Å; L383-L391 HydrophobicContact CB-CD2 4.17Å; L383-L391 HydrophobicContact CB-CG 4.05Å; L383-L391 HydrophobicContact CD2-CD2 3.68Å; L383-L391 HydrophobicContact CD2-CG 4.37Å; Y388-L391 HydrophobicContact CD1-CD1 3.96Å; Y388-L391 PolarHBondContact O-N 3.32Å; E389-L391 PolarHBondContact O-N 3.48Å; L391-I393 VanDerWaalsContact C-N 3.34Å; L391-L394 HydrophobicContact CD2-CD2 4.33Å; L391-L394 PolarHBondContact O-N 3.01Å; L391-T395 WeakPolarHBondContact O-CG2 3.47Å; L391-T395 PolarHBondContact O-N 3.39Å; L391-T395 PolarHBondContact O-OG1 3.11Å; L391-T395 VanDerWaalsContact O-OG1 3.05Å; L391-Y417 HydrophobicContact CD1-CE1 3.84Å; L391-Y417 HydrophobicContact CD1-CE2 3.87Å; L391-Y417 VanDerWaalsContact CD1-CZ 3.47Å; L391-Y417 WeakPolarHBondContact CD1-OH 3.48Å; L391-Y417 HydrophobicContact CD2-CD1 4.11Å; L391-Y417 HydrophobicContact CD2-CD2 4.14Å; L391-Y417 HydrophobicContact CD2-CE1 4.24Å; L391-Y417 HydrophobicContact CD2-CE2 4.25Å; L391-Y417 HydrophobicContact CD2-CG 4.05Å; L391-V427 HydrophobicContact CD1-CG1 3.84Å; L391-I428 HydrophobicContact CD2-CD1 4.25Å; L391-L431 HydrophobicContact CB-CD1 3.64Å; L391-L431 HydrophobicContact CD1-CD1 4.45Å
392	K	95.2	Very high	92.9	Very high	84 Å²	84	60.6 Å²	60.6	37%	0.365	29%	0.292	S	S	.	.	H	α-helix	trans	-62.6	-42.6	174.2	-75.2	167	177.8	165.4	0	111.2	N387 Y388 E389 T395 K396 L431	N387-K392 PolarHBondContact ND2-NZ 2.67Å; N387-K392 WeakPolarHBondContact O-CE 3.19Å; N387-K392 PolarHBondContact O-NZ 3.17Å; Y388-K392 WeakPolarHBondContact O-CG 3.43Å; Y388-K392 PolarHBondContact O-N 2.96Å; E389-K392 WeakPolarHBondContact O-CB 3.35Å; E389-K392 PolarHBondContact O-N 3.39Å; K392-T395 WeakPolarHBondContact CA-OG1 3.43Å; K392-T395 PolarHBondContact O-N 2.88Å; K392-T395 PolarHBondContact O-OG1 3.03Å; K392-K396 WeakPolarHBondContact O-CB 3.42Å; K392-K396 PolarHBondContact O-N 2.8Å; K392-L431 HydrophobicContact CG-CD2 3.83Å
393	I	93.3	Very high	92.9	Very high	45 Å²	45	60.4 Å²	60.4	23%	0.231	30%	0.297	C	S	.	.	H	α-helix	trans	-61.7	-49.6	174.2	-65.4	167.4	0	0	0	110.1	L359 K360 E389 L390 L391 T395 K396 L397	L359-I393 HydrophobicContact CB-CG2 4.22Å; L359-I393 WeakPolarHBondContact O-CG2 3.25Å; K360-I393 HydrophobicContact CG-CD1 3.96Å; E389-I393 HydrophobicContact CG-CD1 4.22Å; E389-I393 WeakPolarHBondContact O-CG1 3.32Å; E389-I393 PolarHBondContact O-N 3.32Å; L390-I393 PolarHBondContact O-N 3.49Å; L391-I393 VanDerWaalsContact C-N 3.34Å; I393-T395 PolarHBondContact O-N 3.28Å; I393-K396 WeakPolarHBondContact O-CA 3.32Å; I393-K396 WeakPolarHBondContact O-CB 3.34Å; I393-K396 PolarHBondContact O-N 3.17Å; I393-L397 HydrophobicContact CG2-CD1 4.29Å; I393-L397 HydrophobicContact CG2-CG 4.47Å; I393-L397 WeakPolarHBondContact O-CG 3.45Å; I393-L397 PolarHBondContact O-N 3.44Å
394	L	95.4	Very high	93	Very high	0 Å²	0	62.7 Å²	62.7	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-55.8	-46.4	177.1	179.8	65.3	0	0	0	112.3	L359 L390 L391 K396 L397 L398 A410 D413 V414	L359-L394 HydrophobicContact CD2-CB 3.84Å; L359-L394 HydrophobicContact CD2-CD1 3.73Å; L359-L394 HydrophobicContact CD2-CG 4.35Å; L390-L394 WeakPolarHBondContact O-CB 3.43Å; L390-L394 PolarHBondContact O-N 2.94Å; L391-L394 HydrophobicContact CD2-CD2 4.33Å; L391-L394 PolarHBondContact O-N 3.01Å; L394-K396 VanDerWaalsContact C-N 3.3Å; L394-K396 PolarHBondContact O-N 3.16Å; L394-L397 PolarHBondContact O-N 3.07Å; L394-L398 PolarHBondContact O-N 2.99Å; L394-L398 VanDerWaalsContact O-N 3.17Å; L394-A410 HydrophobicContact CD1-CB 3.6Å; L394-D413 HydrophobicContact CD1-CB 4.12Å; L394-D413 HydrophobicContact CD2-CB 4.04Å; L394-V414 HydrophobicContact CD2-CG2 3.73Å; L394-V414 HydrophobicContact CG-CG2 4.1Å
395	T	94.8	Very high	93	Very high	13 Å²	13	65.1 Å²	65.1	8%	0.08	32%	0.323	C	S	.	.	H	α-helix	trans	-65.9	-33.9	175.5	50.8	0	0	0	0	112.5	L391 K392 I393 L398 E399 L431 L436	L391-T395 WeakPolarHBondContact O-CG2 3.47Å; L391-T395 PolarHBondContact O-N 3.39Å; L391-T395 PolarHBondContact O-OG1 3.11Å; L391-T395 VanDerWaalsContact O-OG1 3.05Å; K392-T395 WeakPolarHBondContact CA-OG1 3.43Å; K392-T395 PolarHBondContact O-N 2.88Å; K392-T395 PolarHBondContact O-OG1 3.03Å; I393-T395 PolarHBondContact O-N 3.28Å; T395-L398 PolarHBondContact O-N 2.59Å; T395-E399 PolarHBondContact O-N 3.15Å; T395-E399 VanDerWaalsContact O-N 3.16Å; T395-L431 HydrophobicContact CG2-CB 4.09Å; T395-L436 WeakPolarHBondContact O-CD1 3.39Å
396	K	94.4	Very high	93.2	Very high	104 Å²	104	60.7 Å²	60.7	45%	0.452	30%	0.303	S	S	.	.	H	α-helix	trans	-68.3	-41.4	177.3	-172.2	60.2	179.4	170.6	0	111.1	K392 I393 L394 L398 E399 V400	K392-K396 WeakPolarHBondContact O-CB 3.42Å; K392-K396 PolarHBondContact O-N 2.8Å; I393-K396 WeakPolarHBondContact O-CA 3.32Å; I393-K396 WeakPolarHBondContact O-CB 3.34Å; I393-K396 PolarHBondContact O-N 3.17Å; L394-K396 VanDerWaalsContact C-N 3.3Å; L394-K396 PolarHBondContact O-N 3.16Å; K396-L398 VanDerWaalsContact C-N 3.3Å; K396-L398 PolarHBondContact O-N 3.01Å; K396-E399 VanDerWaalsContact CD-OE2 3.29Å; K396-E399 WeakPolarHBondContact CD-OE2 3.33Å; K396-E399 IonicContact NZ-OE2 3.79Å; K396-E399 PolarHBondContact NZ-OE2 3.3Å; K396-E399 WeakPolarHBondContact O-CA 3.4Å; K396-E399 WeakPolarHBondContact O-CB 3.16Å; K396-E399 PolarHBondContact O-N 3.08Å; K396-V400 HydrophobicContact CD-CG1 3.96Å; K396-V400 HydrophobicContact CG-CG2 4.41Å; K396-V400 WeakPolarHBondContact O-CG2 3.44Å; K396-V400 PolarHBondContact O-N 2.83Å
397	L	94.2	Very high	93.5	Very high	22 Å²	22	53.8 Å²	53.8	12%	0.115	27%	0.272	C	S	.	.	H	α-helix	trans	-59	-41.6	174.2	-66.8	172.2	0	0	0	111.4	L359 L364 I393 L394 E399 S401 V406	L359-L397 HydrophobicContact CD2-CD1 4.15Å; L364-L397 HydrophobicContact CD1-CD1 4Å; L364-L397 HydrophobicContact CG-CD1 4.27Å; I393-L397 HydrophobicContact CG2-CD1 4.29Å; I393-L397 HydrophobicContact CG2-CG 4.47Å; I393-L397 WeakPolarHBondContact O-CG 3.45Å; I393-L397 PolarHBondContact O-N 3.44Å; L394-L397 PolarHBondContact O-N 3.07Å; L397-E399 PolarHBondContact O-N 3.13Å; L397-S401 WeakPolarHBondContact O-CB 3.29Å; L397-S401 PolarHBondContact O-N 3.11Å; L397-V406 HydrophobicContact CB-CG1 4.38Å
398	L	93.8	Very high	93.7	Very high	2 Å²	2	48.5 Å²	48.5	1%	0.01	24%	0.244	C	C	.	.	H	α-helix	trans	-62.6	-27.1	172.6	-76.5	171.6	0	0	0	113.8	L394 T395 K396 L407 A410 A411 V414 L436 V437 H440	L394-L398 PolarHBondContact O-N 2.99Å; L394-L398 VanDerWaalsContact O-N 3.17Å; T395-L398 PolarHBondContact O-N 2.59Å; K396-L398 VanDerWaalsContact C-N 3.3Å; K396-L398 PolarHBondContact O-N 3.01Å; L398-L407 HydrophobicContact CD2-CD2 4.29Å; L398-A410 HydrophobicContact CD2-CB 3.74Å; L398-A410 HydrophobicContact CG-CB 3.79Å; L398-A411 HydrophobicContact CD2-CB 4.19Å; L398-V414 HydrophobicContact CD1-CG2 3.76Å; L398-L436 HydrophobicContact CB-CB 4.29Å; L398-L436 HydrophobicContact CB-CD1 4.25Å; L398-V437 HydrophobicContact CD1-CG2 3.8Å; L398-H440 PolarHBondContact O-NE2 3.45Å
399	E	94.1	Very high	93.9	Very high	117 Å²	117	45.1 Å²	45.1	55%	0.547	23%	0.231	S	C	.	.	H	α-helix	trans	-84.5	-38.8	-179.4	-172.6	-172.4	-156.9	0	0	112.6	T395 K396 L397 L436	T395-E399 PolarHBondContact O-N 3.15Å; T395-E399 VanDerWaalsContact O-N 3.16Å; K396-E399 VanDerWaalsContact CD-OE2 3.29Å; K396-E399 WeakPolarHBondContact CD-OE2 3.33Å; K396-E399 IonicContact NZ-OE2 3.79Å; K396-E399 PolarHBondContact NZ-OE2 3.3Å; K396-E399 WeakPolarHBondContact O-CA 3.4Å; K396-E399 WeakPolarHBondContact O-CB 3.16Å; K396-E399 PolarHBondContact O-N 3.08Å; L397-E399 PolarHBondContact O-N 3.13Å; E399-L436 HydrophobicContact CB-CD1 4.09Å; E399-L436 HydrophobicContact CB-CD2 4.14Å; E399-L436 HydrophobicContact CG-CD2 4.24Å
400	V	92.5	Very high	94.1	Very high	82 Å²	82	41.8 Å²	41.8	50%	0.497	22%	0.215	S	C	.	.	H	α-helix	trans	-116.2	-11	-167.2	-51.8	0	0	0	0	115.6	K396	K396-V400 HydrophobicContact CD-CG1 3.96Å; K396-V400 HydrophobicContact CG-CG2 4.41Å; K396-V400 WeakPolarHBondContact O-CG2 3.44Å; K396-V400 PolarHBondContact O-N 2.83Å
401	S	90.8	Very high	94.2	Very high	25 Å²	25	41.1 Å²	41.1	18%	0.175	21%	0.212	C	C	.	.			trans	-78.6	133.1	-179.8	-174.6	0	0	0	0	110.8	L397 D403 L407	L397-S401 WeakPolarHBondContact O-CB 3.29Å; L397-S401 PolarHBondContact O-N 3.11Å; S401-D403 PolarHBondContact OG-N 3.37Å; S401-L407 WeakPolarHBondContact O-CD1 3.26Å
402	D	89.2	Confident	94.3	Very high	153 Å²	153	42.4 Å²	42.4	82%	0.818	22%	0.218	S	C	*	.			trans	-96.8	-6.7	170.4	-62.6	-43.5	0	0	0	112.4	P404	D402-P404 VanDerWaalsContact O-CD 3.29Å; D402-P404 WeakPolarHBondContact O-CD 3.33Å
403	D	91.8	Very high	94.3	Very high	81 Å²	81	38.4 Å²	38.4	43%	0.433	20%	0.2	S	C	.	.			trans	-77.4	115.7	178.6	-175.1	-20.8	0	0	0	110.8	S401 Q405 V406 L407	S401-D403 PolarHBondContact OG-N 3.37Å; D403-Q405 PolarHBondContact O-N 3.03Å; D403-Q405 WeakPolarHBondContact OD1-CB 3.16Å; D403-Q405 PolarHBondContact OD1-N 3.43Å; D403-V406 HydrophobicContact CB-CB 4.08Å; D403-V406 HydrophobicContact CB-CG2 3.89Å; D403-V406 PolarHBondContact O-N 3.23Å; D403-L407 WeakPolarHBondContact O-CG 3.34Å; D403-L407 PolarHBondContact O-N 3.36Å
404	P	94	Very high	94.5	Very high	49 Å²	49	36.2 Å²	36.2	32%	0.318	19%	0.189	S	C	.	.	H	α-helix	trans	-58.9	-32.7	179.5	-23.9	34.9	0	0	0	113.7	D402 A408 D445 V448	D402-P404 VanDerWaalsContact O-CD 3.29Å; D402-P404 WeakPolarHBondContact O-CD 3.33Å; P404-A408 VanDerWaalsContact O-CB 3.23Å; P404-A408 WeakPolarHBondContact O-CB 3.23Å; P404-A408 PolarHBondContact O-N 2.83Å; P404-D445 HydrophobicContact CB-CB 3.91Å; P404-D445 HydrophobicContact CG-CB 4.42Å; P404-V448 HydrophobicContact CB-CG2 3.92Å; P404-V448 WeakPolarHBondContact O-CG2 3.2Å
405	Q	94	Very high	94.4	Very high	79 Å²	79	36.2 Å²	36.2	37%	0.369	19%	0.189	S	C	.	.	H	α-helix	trans	-67.9	-47.2	178.7	-175.3	175.7	-62.4	0	0	110.7	L364 D403 L407 A408 V409	L364-Q405 PolarHBondContact O-NE2 2.94Å; D403-Q405 PolarHBondContact O-N 3.03Å; D403-Q405 WeakPolarHBondContact OD1-CB 3.16Å; D403-Q405 PolarHBondContact OD1-N 3.43Å; Q405-L407 VanDerWaalsContact C-N 3.33Å; Q405-L407 PolarHBondContact O-N 3.23Å; Q405-A408 PolarHBondContact O-N 2.72Å; Q405-V409 WeakPolarHBondContact O-CG2 3.21Å; Q405-V409 PolarHBondContact O-N 3.06Å
406	V	94.9	Very high	94.4	Very high	4 Å²	4	36.3 Å²	36.3	2%	0.024	19%	0.189	C	C	.	.	H	α-helix	trans	-61.3	-44.5	177.9	176.1	0	0	0	0	110.4	L364 L397 D403 A408 V409 A410	L364-V406 HydrophobicContact CB-CG1 4.35Å; L364-V406 HydrophobicContact CB-CG2 4.47Å; L364-V406 HydrophobicContact CD1-CG1 4.09Å; L364-V406 HydrophobicContact CG-CG1 4.18Å; L397-V406 HydrophobicContact CB-CG1 4.38Å; D403-V406 HydrophobicContact CB-CB 4.08Å; D403-V406 HydrophobicContact CB-CG2 3.89Å; D403-V406 PolarHBondContact O-N 3.23Å; V406-A408 PolarHBondContact O-N 2.95Å; V406-V409 PolarHBondContact O-N 3.01Å; V406-A410 WeakPolarHBondContact O-CB 3.4Å; V406-A410 PolarHBondContact O-N 3.41Å
407	L	96.2	Very high	94.4	Very high	2 Å²	2	31.3 Å²	31.3	1%	0.01	17%	0.167	C	C	.	.	H	α-helix	trans	-62	-41.7	176.7	-70.1	177.7	0	0	0	112.4	L398 S401 D403 Q405 A410 A411 V448	L398-L407 HydrophobicContact CD2-CD2 4.29Å; S401-L407 WeakPolarHBondContact O-CD1 3.26Å; D403-L407 WeakPolarHBondContact O-CG 3.34Å; D403-L407 PolarHBondContact O-N 3.36Å; Q405-L407 VanDerWaalsContact C-N 3.33Å; Q405-L407 PolarHBondContact O-N 3.23Å; L407-A410 PolarHBondContact O-N 2.88Å; L407-A411 VanDerWaalsContact O-CB 3.27Å; L407-A411 WeakPolarHBondContact O-CB 3.45Å; L407-A411 PolarHBondContact O-N 2.75Å; L407-V448 HydrophobicContact CB-CG1 4.09Å; L407-V448 HydrophobicContact CB-CG2 3.89Å
408	A	96	Very high	94.3	Very high	0 Å²	0	31 Å²	31	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-65.2	-46.4	179.6	0	0	0	0	0	112.1	P404 Q405 V406 H412 Q447 V448 N451	P404-A408 VanDerWaalsContact O-CB 3.23Å; P404-A408 WeakPolarHBondContact O-CB 3.23Å; P404-A408 PolarHBondContact O-N 2.83Å; Q405-A408 PolarHBondContact O-N 2.72Å; V406-A408 PolarHBondContact O-N 2.95Å; A408-H412 WeakPolarHBondContact O-CB 3.26Å; A408-H412 PolarHBondContact O-N 3.21Å; A408-H412 VanDerWaalsContact O-N 3.07Å; A408-Q447 HydrophobicContact CB-CB 4.27Å; A408-V448 HydrophobicContact CB-CG2 4.19Å; A408-N451 WeakPolarHBondContact O-CB 3.49Å
409	V	96.6	Very high	94.2	Very high	0 Å²	0	35.2 Å²	35.2	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-64.8	-45.3	176	178.7	0	0	0	0	110.2	L364 W366 H370 Q405 V406 A411 H412 D413	L364-V409 HydrophobicContact CB-CB 3.94Å; L364-V409 HydrophobicContact CB-CG1 3.89Å; L364-V409 HydrophobicContact CB-CG2 4.47Å; L364-V409 HydrophobicContact CD1-CB 4.33Å; L364-V409 HydrophobicContact CD1-CG1 4.18Å; W366-V409 HydrophobicContact CD2-CG2 3.72Å; W366-V409 HydrophobicContact CE3-CG2 4.12Å; W366-V409 HydrophobicContact CG-CG2 4.06Å; W366-V409 HydrophobicContact CH2-CG2 4.45Å; W366-V409 HydrophobicContact CZ2-CG2 4.04Å; W366-V409 HydrophobicContact CZ3-CG2 4.48Å; H370-V409 HydrophobicContact CB-CG1 4.17Å; H370-V409 WeakPolarHBondContact ND1-CG1 3.26Å; Q405-V409 WeakPolarHBondContact O-CG2 3.21Å; Q405-V409 PolarHBondContact O-N 3.06Å; V406-V409 PolarHBondContact O-N 3.01Å; V409-A411 VanDerWaalsContact C-N 3.34Å; V409-A411 PolarHBondContact O-N 3.29Å; V409-H412 WeakPolarHBondContact O-CB 3.17Å; V409-H412 PolarHBondContact O-N 2.98Å; V409-D413 WeakPolarHBondContact O-CB 2.93Å; V409-D413 PolarHBondContact O-N 3.06Å
410	A	96.7	Very high	94.1	Very high	0 Å²	0	31.3 Å²	31.3	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-62.9	-41.1	-178.9	0	0	0	0	0	112.4	L364 L394 L398 V406 L407 D413 V414	L364-A410 HydrophobicContact CD1-CB 3.88Å; L394-A410 HydrophobicContact CD1-CB 3.6Å; L398-A410 HydrophobicContact CD2-CB 3.74Å; L398-A410 HydrophobicContact CG-CB 3.79Å; V406-A410 WeakPolarHBondContact O-CB 3.4Å; V406-A410 PolarHBondContact O-N 3.41Å; L407-A410 PolarHBondContact O-N 2.88Å; A410-D413 PolarHBondContact O-N 3.15Å; A410-V414 WeakPolarHBondContact O-CG2 3.45Å; A410-V414 PolarHBondContact O-N 3.38Å; A410-V414 VanDerWaalsContact O-N 3.16Å
411	A	95.8	Very high	94	Very high	0 Å²	0	29.5 Å²	29.5	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-64.1	-43.9	176.1	0	0	0	0	0	111.1	L398 L407 V409 D413 V414 G415 N451 A452 A455	L398-A411 HydrophobicContact CD2-CB 4.19Å; L407-A411 VanDerWaalsContact O-CB 3.27Å; L407-A411 WeakPolarHBondContact O-CB 3.45Å; L407-A411 PolarHBondContact O-N 2.75Å; V409-A411 VanDerWaalsContact C-N 3.34Å; V409-A411 PolarHBondContact O-N 3.29Å; A411-D413 PolarHBondContact O-N 3.35Å; A411-V414 PolarHBondContact O-N 3.32Å; A411-G415 PolarHBondContact O-N 2.91Å; A411-N451 HydrophobicContact CB-CB 4.34Å; A411-A452 HydrophobicContact CB-CB 4.38Å; A411-A455 WeakPolarHBondContact O-CB 3.46Å
412	H	96.3	Very high	93.7	Very high	28 Å²	28	34.3 Å²	34.3	13%	0.13	18%	0.179	C	C	.	.	H	α-helix	trans	-57.4	-49	175.9	171.8	-85.3	0	0	0	112.2	W366 H370 A408 V409 V414 G415 E416 N451	W366-H412 HydrophobicContact CH2-CB 3.63Å; W366-H412 AromaticContact CH2-CD2 3.86Å; W366-H412 AromaticContact CH2-CG 3.59Å; W366-H412 HydrophobicContact CZ3-CB 4.24Å; W366-H412 AromaticContact CZ3-CG 3.81Å; W366-H412 AromaticContact CZ3-ND1 3.87Å; H370-H412 PolarHBondContact O-CE1 2.82Å; A408-H412 WeakPolarHBondContact O-CB 3.26Å; A408-H412 PolarHBondContact O-N 3.21Å; A408-H412 VanDerWaalsContact O-N 3.07Å; V409-H412 WeakPolarHBondContact O-CB 3.17Å; V409-H412 PolarHBondContact O-N 2.98Å; H412-V414 PolarHBondContact O-N 3.44Å; H412-G415 WeakPolarHBondContact O-CA 3.29Å; H412-G415 PolarHBondContact O-N 3.15Å; H412-E416 WeakPolarHBondContact CE1-CG 3.4Å; H412-E416 PolarHBondContact O-N 3.2Å; H412-N451 HydrophobicContact CB-CB 4.25Å
413	D	96.7	Very high	93.7	Very high	0 Å²	0	35.4 Å²	35.4	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-61.1	-39.9	-178.7	-78.7	11.6	0	0	0	113.2	Y355 H370 W376 L394 V409 A410 A411 G415 E416 Y417	Y355-D413 WeakPolarHBondContact CE2-OD2 3.48Å; Y355-D413 PolarHBondContact OH-OD2 2.95Å; H370-D413 IonicContact CE1-OD2 3.71Å; H370-D413 PolarHBondContact CE1-OD2 3.48Å; H370-D413 IonicContact CG-OD1 3.01Å; H370-D413 IonicContact ND1-OD1 3.99Å; H370-D413 PolarHBondContact ND1-OD1 3.39Å; H370-D413 IonicContact ND1-OD2 3.62Å; H370-D413 PolarHBondContact ND1-OD2 3.4Å; W376-D413 HydrophobicContact CH2-CB 3.77Å; W376-D413 HydrophobicContact CZ2-CB 3.89Å; W376-D413 WeakPolarHBondContact CZ2-OD1 3.48Å; L394-D413 HydrophobicContact CD1-CB 4.12Å; L394-D413 HydrophobicContact CD2-CB 4.04Å; V409-D413 WeakPolarHBondContact O-CB 2.93Å; V409-D413 PolarHBondContact O-N 3.06Å; A410-D413 PolarHBondContact O-N 3.15Å; A411-D413 PolarHBondContact O-N 3.35Å; D413-G415 PolarHBondContact O-N 3.37Å; D413-E416 PolarHBondContact O-N 3.5Å; D413-Y417 WeakPolarHBondContact O-CB 3.48Å; D413-Y417 PolarHBondContact O-N 3.39Å
414	V	95.7	Very high	93.5	Very high	0 Å²	0	31.5 Å²	31.5	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-57.2	-43.3	172.2	169.1	0	0	0	0	110.4	L394 L398 A410 A411 H412 V418 I428 V437	L394-V414 HydrophobicContact CD2-CG2 3.73Å; L394-V414 HydrophobicContact CG-CG2 4.1Å; L398-V414 HydrophobicContact CD1-CG2 3.76Å; A410-V414 WeakPolarHBondContact O-CG2 3.45Å; A410-V414 PolarHBondContact O-N 3.38Å; A410-V414 VanDerWaalsContact O-N 3.16Å; A411-V414 PolarHBondContact O-N 3.32Å; H412-V414 PolarHBondContact O-N 3.44Å; V414-V418 WeakPolarHBondContact O-CG2 3.26Å; V414-V418 PolarHBondContact O-N 3.08Å; V414-V418 VanDerWaalsContact O-N 3.14Å; V414-I428 HydrophobicContact CG1-CD1 4.14Å; V414-I428 HydrophobicContact CG1-CG1 4.16Å; V414-I428 HydrophobicContact CG1-CG2 3.76Å; V414-I428 HydrophobicContact CG2-CD1 4.5Å; V414-V437 HydrophobicContact CB-CG2 4.3Å; V414-V437 HydrophobicContact CG1-CG2 4.07Å; V414-V437 HydrophobicContact CG2-CG2 4.45Å
415	G	93.7	Very high	93.3	Very high	0 Å²	0	31.5 Å²	31.5	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-63.1	-45.8	176.1	0	0	0	0	0	112.9	A411 H412 D413 V418 R419 K458	A411-G415 PolarHBondContact O-N 2.91Å; H412-G415 WeakPolarHBondContact O-CA 3.29Å; H412-G415 PolarHBondContact O-N 3.15Å; D413-G415 PolarHBondContact O-N 3.37Å; G415-V418 PolarHBondContact O-N 2.9Å; G415-R419 WeakPolarHBondContact O-CB 3.15Å; G415-R419 PolarHBondContact O-N 3.01Å; G415-K458 WeakPolarHBondContact O-CD 3.45Å
416	E	94.4	Very high	93.1	Very high	14 Å²	14	36.3 Å²	36.3	7%	0.065	16%	0.161	C	C	.	.	H	α-helix	trans	-66.3	-39.5	179.3	-73.4	-56.9	132.8	0	0	113.1	W376 H412 D413 R419 H420 K458	W376-E416 HydrophobicContact CD2-CB 3.56Å; W376-E416 HydrophobicContact CD2-CG 4.49Å; W376-E416 HydrophobicContact CE3-CB 4.04Å; W376-E416 HydrophobicContact CG-CB 3.86Å; W376-E416 HydrophobicContact CG-CG 4.45Å; W376-E416 HydrophobicContact CH2-CB 4.4Å; W376-E416 HydrophobicContact CZ2-CB 3.99Å; W376-E416 HydrophobicContact CZ3-CB 4.43Å; H412-E416 WeakPolarHBondContact CE1-CG 3.4Å; H412-E416 PolarHBondContact O-N 3.2Å; D413-E416 PolarHBondContact O-N 3.5Å; E416-R419 PolarHBondContact O-N 2.99Å; E416-R419 IonicContact OE1-NH1 3.17Å; E416-R419 IonicContact OE2-NH1 3.34Å; E416-H420 WeakPolarHBondContact O-CB 3.34Å; E416-H420 PolarHBondContact O-N 2.98Å; E416-H420 PolarHBondContact O-ND1 2.9Å; E416-H420 IonicContact OE2-CE1 2.85Å; E416-H420 PolarHBondContact OE2-CE1 3.25Å; E416-H420 IonicContact OE2-ND1 2.7Å; E416-H420 PolarHBondContact OE2-ND1 3.41Å; E416-K458 IonicContact OE1-NZ 2.81Å; E416-K458 PolarHBondContact OE1-NZ 3.15Å
417	Y	95.1	Very high	93	Very high	0 Å²	0	36.5 Å²	36.5	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-60	-46.1	173.1	170.4	-100.4	0	0	0	111.6	A380 L383 N384 L391 D413 R419 H420 Y421 G424 V427 I428	A380-Y417 HydrophobicContact CB-CD2 4.38Å; A380-Y417 VanDerWaalsContact O-CE2 3.28Å; A380-Y417 WeakPolarHBondContact O-CE2 3.35Å; L383-Y417 HydrophobicContact CB-CD2 4.15Å; L383-Y417 HydrophobicContact CB-CE2 4.04Å; L383-Y417 HydrophobicContact CD2-CD2 4.09Å; N384-Y417 PolarHBondContact OD1-OH 2.89Å; L391-Y417 HydrophobicContact CD1-CE1 3.84Å; L391-Y417 HydrophobicContact CD1-CE2 3.87Å; L391-Y417 VanDerWaalsContact CD1-CZ 3.47Å; L391-Y417 WeakPolarHBondContact CD1-OH 3.48Å; L391-Y417 HydrophobicContact CD2-CD1 4.11Å; L391-Y417 HydrophobicContact CD2-CD2 4.14Å; L391-Y417 HydrophobicContact CD2-CE1 4.24Å; L391-Y417 HydrophobicContact CD2-CE2 4.25Å; L391-Y417 HydrophobicContact CD2-CG 4.05Å; D413-Y417 WeakPolarHBondContact O-CB 3.48Å; D413-Y417 PolarHBondContact O-N 3.39Å; Y417-R419 VanDerWaalsContact C-N 3.32Å; Y417-R419 PolarHBondContact O-N 2.89Å; Y417-H420 PolarHBondContact O-N 3.42Å; Y417-Y421 HydrophobicContact CE1-CD1 4.25Å; Y417-Y421 HydrophobicContact CE2-CD1 4.04Å; Y417-Y421 HydrophobicContact CE2-CG 4.29Å; Y417-Y421 AromaticContact CZ-CD1 3.58Å; Y417-Y421 WeakPolarHBondContact O-CB 3.34Å; Y417-Y421 PolarHBondContact O-N 2.99Å; Y417-Y421 WeakPolarHBondContact OH-CD1 3.24Å; Y417-Y421 WeakPolarHBondContact OH-CE1 3.46Å; Y417-G424 VanDerWaalsContact CE1-CA 3.45Å; Y417-V427 HydrophobicContact CE1-CB 4.44Å; Y417-I428 HydrophobicContact CD1-CD1 3.97Å; Y417-I428 HydrophobicContact CD1-CG1 3.87Å; Y417-I428 HydrophobicContact CE1-CD1 4.15Å; Y417-I428 HydrophobicContact CE1-CG1 3.99Å
418	V	93.1	Very high	92.9	Very high	16 Å²	16	36.4 Å²	36.4	10%	0.097	16%	0.161	C	C	.	.	H	α-helix	trans	-64.6	-38.5	178.7	172.5	0	0	0	0	111.6	V414 G415 H420 K425 I428 L459	V414-V418 WeakPolarHBondContact O-CG2 3.26Å; V414-V418 PolarHBondContact O-N 3.08Å; V414-V418 VanDerWaalsContact O-N 3.14Å; G415-V418 PolarHBondContact O-N 2.9Å; V418-H420 VanDerWaalsContact C-N 3.34Å; V418-K425 HydrophobicContact CG1-CB 4.33Å; V418-I428 HydrophobicContact CG2-CB 4.44Å; V418-I428 HydrophobicContact CG2-CG1 3.84Å; V418-L459 HydrophobicContact CB-CD2 4.35Å; V418-L459 HydrophobicContact CG1-CD2 4.02Å; V418-L459 HydrophobicContact CG1-CG 4.38Å; V418-L459 HydrophobicContact CG2-CD2 3.55Å; V418-L459 HydrophobicContact CG2-CG 4.15Å
419	R	90.9	Very high	92.7	Very high	90 Å²	90	40 Å²	40	34%	0.34	18%	0.178	S	C	.	.	H	α-helix	trans	-63.1	-40.7	176.8	175.6	-179	171.1	-177.2	-1.4	112	E373 G415 E416 Y417	E373-R419 IonicContact OE1-NH2 3.13Å; E373-R419 PolarHBondContact OE1-NH2 3.44Å; E373-R419 IonicContact OE2-NH2 2.58Å; G415-R419 WeakPolarHBondContact O-CB 3.15Å; G415-R419 PolarHBondContact O-N 3.01Å; E416-R419 PolarHBondContact O-N 2.99Å; E416-R419 IonicContact OE1-NH1 3.17Å; E416-R419 IonicContact OE2-NH1 3.34Å; Y417-R419 VanDerWaalsContact C-N 3.32Å; Y417-R419 PolarHBondContact O-N 2.89Å
420	H	91	Very high	92.4	Very high	35 Å²	35	47.5 Å²	47.5	16%	0.162	21%	0.213	C	C	.	.	H	α-helix	trans	-97.2	-11.1	-172.3	-68.8	95.8	0	0	0	114.2	W376 A380 E416 Y417 V418	W376-H420 HydrophobicContact CB-CB 4.4Å; A380-H420 HydrophobicContact CB-CB 3.77Å; E416-H420 WeakPolarHBondContact O-CB 3.34Å; E416-H420 PolarHBondContact O-N 2.98Å; E416-H420 PolarHBondContact O-ND1 2.9Å; E416-H420 IonicContact OE2-CE1 2.85Å; E416-H420 PolarHBondContact OE2-CE1 3.25Å; E416-H420 IonicContact OE2-ND1 2.7Å; E416-H420 PolarHBondContact OE2-ND1 3.41Å; Y417-H420 PolarHBondContact O-N 3.42Å; V418-H420 VanDerWaalsContact C-N 3.34Å
421	Y	91.3	Very high	92.2	Very high	43 Å²	43	49.6 Å²	49.6	17%	0.169	22%	0.224	C	C	.	.			trans	-120.3	109	174.2	-174	-122.1	0	0	0	111	V381 Y417 R423 G424 V427	V381-Y421 HydrophobicContact CG2-CD2 4.1Å; V381-Y421 HydrophobicContact CG2-CE2 4.43Å; Y417-Y421 HydrophobicContact CE1-CD1 4.25Å; Y417-Y421 HydrophobicContact CE2-CD1 4.04Å; Y417-Y421 HydrophobicContact CE2-CG 4.29Å; Y417-Y421 AromaticContact CZ-CD1 3.58Å; Y417-Y421 WeakPolarHBondContact O-CB 3.34Å; Y417-Y421 PolarHBondContact O-N 2.99Å; Y417-Y421 WeakPolarHBondContact OH-CD1 3.24Å; Y417-Y421 WeakPolarHBondContact OH-CE1 3.46Å; Y421-R423 HydrophobicContact CD1-CB 4.3Å; Y421-R423 HydrophobicContact CE1-CB 3.64Å; Y421-R423 PolarHBondContact O-N 3.46Å; Y421-G424 VanDerWaalsContact CD1-CA 3.45Å; Y421-G424 WeakPolarHBondContact O-CA 3.44Å; Y421-G424 PolarHBondContact O-N 3.27Å; Y421-V427 HydrophobicContact CE1-CG2 4.31Å
422	P	85.1	Confident	92	Very high	127 Å²	127	51.2 Å²	51.2	83%	0.825	24%	0.241	S	C	*	.	T	Hydrogen-bonded Turn	trans	-56.9	-26.9	-174.2	-29.3	35.3	0	0	0	115.7
423	R	88.1	Confident	91.8	Very high	175 Å²	175	49.9 Å²	49.9	66%	0.66	24%	0.235	S	C	*	.	T	Hydrogen-bonded Turn	trans	-94.8	-0.2	175.8	-64.8	-177.8	-179.9	-179.6	1.2	113.3	Y421 K425 R426 V427	Y421-R423 HydrophobicContact CD1-CB 4.3Å; Y421-R423 HydrophobicContact CE1-CB 3.64Å; Y421-R423 PolarHBondContact O-N 3.46Å; R423-K425 VanDerWaalsContact C-N 3.28Å; R423-K425 PolarHBondContact O-N 3.03Å; R423-R426 PolarHBondContact O-N 3.49Å; R423-R426 VanDerWaalsContact O-N 3.14Å; R423-V427 PolarHBondContact O-N 3.27Å
424	G	88.4	Confident	91.5	Very high	0 Å²	0	52.7 Å²	52.7	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-61.1	-34.5	-172.9	0	0	0	0	0	113.3	Y417 Y421 R426 V427 I428	Y417-G424 VanDerWaalsContact CE1-CA 3.45Å; Y421-G424 VanDerWaalsContact CD1-CA 3.45Å; Y421-G424 WeakPolarHBondContact O-CA 3.44Å; Y421-G424 PolarHBondContact O-N 3.27Å; G424-R426 VanDerWaalsContact C-N 3.33Å; G424-R426 PolarHBondContact O-N 2.59Å; G424-V427 PolarHBondContact O-N 3.08Å; G424-V427 VanDerWaalsContact O-N 3.13Å; G424-I428 WeakPolarHBondContact O-CG1 3.4Å; G424-I428 PolarHBondContact O-N 3.17Å
425	K	89.1	Confident	91.3	Very high	49 Å²	49	57.8 Å²	57.8	21%	0.213	27%	0.271	C	S	.	.	H	α-helix	trans	-53	-48.5	174.2	-179.2	175.8	-179.1	161.8	0	112.6	V418 R423 V427 E429 L459	V418-K425 HydrophobicContact CG1-CB 4.33Å; R423-K425 VanDerWaalsContact C-N 3.28Å; R423-K425 PolarHBondContact O-N 3.03Å; K425-V427 VanDerWaalsContact C-N 3.33Å; K425-V427 PolarHBondContact O-N 2.89Å; K425-E429 WeakPolarHBondContact O-CB 3.47Å; K425-E429 VanDerWaalsContact O-CG 3.3Å; K425-E429 WeakPolarHBondContact O-CG 3.06Å; K425-E429 PolarHBondContact O-N 3.31Å; K425-L459 VanDerWaalsContact CD-O 3.3Å; K425-L459 WeakPolarHBondContact CD-O 3.44Å; K425-L459 WeakPolarHBondContact CE-O 3.4Å; K425-L459 HydrophobicContact CG-CD2 4.29Å; K425-L459 PolarHBondContact NZ-O 3.34Å
426	R	90.3	Very high	91.3	Very high	180 Å²	180	59.5 Å²	59.5	68%	0.679	28%	0.279	S	S	*	.	H	α-helix	trans	-66	-38.8	-179.8	-66.3	-177.7	-176.9	175.3	0.9	111.5	R423 G424 E429 Q430	R423-R426 PolarHBondContact O-N 3.49Å; R423-R426 VanDerWaalsContact O-N 3.14Å; G424-R426 VanDerWaalsContact C-N 3.33Å; G424-R426 PolarHBondContact O-N 2.59Å; R426-E429 PolarHBondContact O-N 3.01Å; R426-Q430 WeakPolarHBondContact O-CB 3.34Å; R426-Q430 VanDerWaalsContact O-CG 3.27Å; R426-Q430 WeakPolarHBondContact O-CG 3.35Å; R426-Q430 PolarHBondContact O-N 3.3Å
427	V	92.8	Very high	91.2	Very high	8 Å²	8	58.8 Å²	58.8	5%	0.048	28%	0.276	C	S	.	.	H	α-helix	trans	-65.4	-49.6	179.2	179.2	0	0	0	0	110.4	Y388 L391 Y417 Y421 R423 G424 K425 E429 Q430 L431	Y388-V427 HydrophobicContact CD1-CG1 3.67Å; Y388-V427 HydrophobicContact CE1-CG1 3.74Å; Y388-V427 HydrophobicContact CE1-CG2 4.07Å; Y388-V427 HydrophobicContact CG-CG1 4.32Å; L391-V427 HydrophobicContact CD1-CG1 3.84Å; Y417-V427 HydrophobicContact CE1-CB 4.44Å; Y421-V427 HydrophobicContact CE1-CG2 4.31Å; R423-V427 PolarHBondContact O-N 3.27Å; G424-V427 PolarHBondContact O-N 3.08Å; G424-V427 VanDerWaalsContact O-N 3.13Å; K425-V427 VanDerWaalsContact C-N 3.33Å; K425-V427 PolarHBondContact O-N 2.89Å; V427-E429 VanDerWaalsContact C-N 3.3Å; V427-E429 PolarHBondContact O-N 3.28Å; V427-Q430 PolarHBondContact O-N 3.47Å; V427-Q430 VanDerWaalsContact O-N 3.17Å; V427-L431 HydrophobicContact CG1-CD1 4.07Å; V427-L431 WeakPolarHBondContact O-CG 3.34Å; V427-L431 PolarHBondContact O-N 3.49Å
428	I	93.7	Very high	90.9	Very high	0 Å²	0	62.3 Å²	62.3	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-63.5	-35.9	178.1	-65.8	-59.8	0	0	0	111.8	L391 V414 Y417 V418 G424 L431 G432 G433 L459	L391-I428 HydrophobicContact CD2-CD1 4.25Å; V414-I428 HydrophobicContact CG1-CD1 4.14Å; V414-I428 HydrophobicContact CG1-CG1 4.16Å; V414-I428 HydrophobicContact CG1-CG2 3.76Å; V414-I428 HydrophobicContact CG2-CD1 4.5Å; Y417-I428 HydrophobicContact CD1-CD1 3.97Å; Y417-I428 HydrophobicContact CD1-CG1 3.87Å; Y417-I428 HydrophobicContact CE1-CD1 4.15Å; Y417-I428 HydrophobicContact CE1-CG1 3.99Å; V418-I428 HydrophobicContact CG2-CB 4.44Å; V418-I428 HydrophobicContact CG2-CG1 3.84Å; G424-I428 WeakPolarHBondContact O-CG1 3.4Å; G424-I428 PolarHBondContact O-N 3.17Å; I428-L431 PolarHBondContact O-N 3.34Å; I428-G432 PolarHBondContact O-N 3.17Å; I428-G433 PolarHBondContact O-N 3.17Å; I428-L459 HydrophobicContact CB-CD2 4.46Å; I428-L459 HydrophobicContact CG2-CD2 4.22Å
429	E	91.1	Very high	90.9	Very high	76 Å²	76	66 Å²	66	36%	0.355	31%	0.313	S	S	.	.	H	α-helix	trans	-64	-44	172.5	-78.3	176.9	167.4	0	0	112.1	K425 R426 V427 L431 G432 K434	K425-E429 WeakPolarHBondContact O-CB 3.47Å; K425-E429 VanDerWaalsContact O-CG 3.3Å; K425-E429 WeakPolarHBondContact O-CG 3.06Å; K425-E429 PolarHBondContact O-N 3.31Å; R426-E429 PolarHBondContact O-N 3.01Å; V427-E429 VanDerWaalsContact C-N 3.3Å; V427-E429 PolarHBondContact O-N 3.28Å; E429-L431 VanDerWaalsContact C-N 3.32Å; E429-L431 PolarHBondContact O-N 2.94Å; E429-G432 PolarHBondContact O-N 3.3Å; E429-G432 VanDerWaalsContact O-N 3.15Å; E429-K434 HydrophobicContact CG-CB 4.09Å; E429-K434 HydrophobicContact CG-CD 3.58Å; E429-K434 HydrophobicContact CG-CG 4.49Å; E429-K434 WeakPolarHBondContact OE1-CD 3.31Å; E429-K434 IonicContact OE1-NZ 3.08Å; E429-K434 PolarHBondContact OE1-NZ 3.29Å
430	Q	92.1	Very high	91	Very high	156 Å²	156	63 Å²	63	73%	0.729	30%	0.303	S	S	*	.	H	α-helix	trans	-64.7	-34.2	177.2	-75.9	173.8	-6.3	0	0	113.2	R426 V427 G432	R426-Q430 WeakPolarHBondContact O-CB 3.34Å; R426-Q430 VanDerWaalsContact O-CG 3.27Å; R426-Q430 WeakPolarHBondContact O-CG 3.35Å; R426-Q430 PolarHBondContact O-N 3.3Å; V427-Q430 PolarHBondContact O-N 3.47Å; V427-Q430 VanDerWaalsContact O-N 3.17Å; Q430-G432 PolarHBondContact O-N 3.02Å
431	L	92	Very high	91.1	Very high	45 Å²	45	63.9 Å²	63.9	24%	0.236	31%	0.307	C	S	.	.	T	Hydrogen-bonded Turn	trans	-82.1	1.3	176.8	-63	177	0	0	0	113.1	L391 K392 T395 V427 I428 E429 G433	L391-L431 HydrophobicContact CB-CD1 3.64Å; L391-L431 HydrophobicContact CD1-CD1 4.45Å; K392-L431 HydrophobicContact CG-CD2 3.83Å; T395-L431 HydrophobicContact CG2-CB 4.09Å; V427-L431 HydrophobicContact CG1-CD1 4.07Å; V427-L431 WeakPolarHBondContact O-CG 3.34Å; V427-L431 PolarHBondContact O-N 3.49Å; I428-L431 PolarHBondContact O-N 3.34Å; E429-L431 VanDerWaalsContact C-N 3.32Å; E429-L431 PolarHBondContact O-N 2.94Å; L431-G433 PolarHBondContact O-N 3.21Å
432	G	91.8	Very high	91	Very high	34 Å²	34	69.2 Å²	69.2	35%	0.351	33%	0.334	S	S	.	.	T	Hydrogen-bonded Turn	trans	75.2	-0.2	-179.1	0	0	0	0	0	115	I428 E429 Q430 K434 Q435 L436	I428-G432 PolarHBondContact O-N 3.17Å; E429-G432 PolarHBondContact O-N 3.3Å; E429-G432 VanDerWaalsContact O-N 3.15Å; Q430-G432 PolarHBondContact O-N 3.02Å; G432-K434 VanDerWaalsContact C-N 3.27Å; G432-K434 PolarHBondContact O-N 3.22Å; G432-Q435 PolarHBondContact O-N 3.33Å; G432-L436 PolarHBondContact O-N 2.83Å
433	G	91.4	Very high	91.5	Very high	0 Å²	0	65.6 Å²	65.6	0%	0	31%	0.305	C	S	.	.	H	α-helix	trans	-61.3	-31.2	-176.2	0	0	0	0	0	113.8	I428 L431 Q435 L436 V437	I428-G433 PolarHBondContact O-N 3.17Å; L431-G433 PolarHBondContact O-N 3.21Å; G433-Q435 PolarHBondContact O-N 2.84Å; G433-L436 PolarHBondContact O-N 3.2Å; G433-V437 WeakPolarHBondContact O-CG2 3.26Å; G433-V437 PolarHBondContact O-N 3.49Å
434	K	89.8	Confident	91.8	Very high	58 Å²	58	65.9 Å²	65.9	25%	0.252	31%	0.314	S	S	.	.	H	α-helix	trans	-58.4	-45.5	177.3	179.8	178.8	179.5	-177.8	0	112.3	E429 G432 M438	E429-K434 HydrophobicContact CG-CB 4.09Å; E429-K434 HydrophobicContact CG-CD 3.58Å; E429-K434 HydrophobicContact CG-CG 4.49Å; E429-K434 WeakPolarHBondContact OE1-CD 3.31Å; E429-K434 IonicContact OE1-NZ 3.08Å; E429-K434 PolarHBondContact OE1-NZ 3.29Å; G432-K434 VanDerWaalsContact C-N 3.27Å; G432-K434 PolarHBondContact O-N 3.22Å; K434-M438 HydrophobicContact CG-SD 4.28Å; K434-M438 WeakPolarHBondContact O-CB 2.88Å; K434-M438 WeakPolarHBondContact O-CG 3.46Å; K434-M438 PolarHBondContact O-N 2.91Å
435	Q	91.8	Very high	92.1	Very high	108 Å²	108	68.6 Å²	68.6	51%	0.505	33%	0.329	S	S	.	.	H	α-helix	trans	-68.4	-39	-179.7	-172.1	61.8	47.4	0	0	110.8	G432 G433 M438 N439	G432-Q435 PolarHBondContact O-N 3.33Å; G433-Q435 PolarHBondContact O-N 2.84Å; Q435-M438 PolarHBondContact O-N 3.46Å; Q435-N439 PolarHBondContact NE2-OD1 3.36Å; Q435-N439 PolarHBondContact O-N 3.39Å; Q435-N439 PolarHBondContact O-OD1 3.03Å
436	L	93.2	Very high	92.4	Very high	35 Å²	35	73.4 Å²	73.4	18%	0.183	35%	0.352	C	S	.	.	H	α-helix	trans	-61.3	-49.6	177.5	-64.2	172.8	0	0	0	111.5	T395 L398 E399 G432 G433 M438 N439 H440	T395-L436 WeakPolarHBondContact O-CD1 3.39Å; L398-L436 HydrophobicContact CB-CB 4.29Å; L398-L436 HydrophobicContact CB-CD1 4.25Å; E399-L436 HydrophobicContact CB-CD1 4.09Å; E399-L436 HydrophobicContact CB-CD2 4.14Å; E399-L436 HydrophobicContact CG-CD2 4.24Å; G432-L436 PolarHBondContact O-N 2.83Å; G433-L436 PolarHBondContact O-N 3.2Å; L436-M438 VanDerWaalsContact C-N 3.33Å; L436-M438 PolarHBondContact O-N 3.49Å; L436-N439 WeakPolarHBondContact O-CB 3.44Å; L436-N439 PolarHBondContact O-N 3.43Å; L436-H440 PolarHBondContact O-CD2 3.2Å; L436-H440 PolarHBondContact O-N 3.14Å
437	V	92.5	Very high	92.5	Very high	0 Å²	0	70 Å²	70	0%	0	34%	0.344	C	S	.	.	H	α-helix	trans	-64.1	-37.9	178	-178.1	0	0	0	0	111.3	L398 V414 G433 N439 H440 M441 A452 A455 V456	L398-V437 HydrophobicContact CD1-CG2 3.8Å; V414-V437 HydrophobicContact CB-CG2 4.3Å; V414-V437 HydrophobicContact CG1-CG2 4.07Å; V414-V437 HydrophobicContact CG2-CG2 4.45Å; G433-V437 WeakPolarHBondContact O-CG2 3.26Å; G433-V437 PolarHBondContact O-N 3.49Å; V437-N439 PolarHBondContact O-N 3.3Å; V437-H440 PolarHBondContact O-N 3.48Å; V437-M441 PolarHBondContact O-N 2.93Å; V437-A452 HydrophobicContact CG1-CB 4.08Å; V437-A452 WeakPolarHBondContact CG1-O 3.27Å; V437-A455 HydrophobicContact CG1-CB 3.69Å; V437-V456 HydrophobicContact CB-CG2 4.47Å; V437-V456 HydrophobicContact CG1-CG2 3.85Å
438	M	89.9	Confident	92.6	Very high	74 Å²	74	69.6 Å²	69.6	37%	0.365	34%	0.342	S	S	.	.	H	α-helix	trans	-63	-39.1	174.3	-77.9	-178.6	59.5	0	0	112.9	K434 Q435 L436 H440 M441 V456	K434-M438 HydrophobicContact CG-SD 4.28Å; K434-M438 WeakPolarHBondContact O-CB 2.88Å; K434-M438 WeakPolarHBondContact O-CG 3.46Å; K434-M438 PolarHBondContact O-N 2.91Å; Q435-M438 PolarHBondContact O-N 3.46Å; L436-M438 VanDerWaalsContact C-N 3.33Å; L436-M438 PolarHBondContact O-N 3.49Å; M438-H440 VanDerWaalsContact C-N 3.33Å; M438-M441 WeakPolarHBondContact O-CB 3.15Å; M438-M441 PolarHBondContact O-N 3.46Å; M438-V456 HydrophobicContact CG-CG2 3.83Å
439	N	92.8	Very high	92.7	Very high	92 Å²	92	74.8 Å²	74.8	49%	0.492	36%	0.361	S	S	.	.	H	α-helix	trans	-63.7	-42.7	175.8	-67	-9.4	0	0	0	110.5	Q435 L436 V437 M441 H442	Q435-N439 PolarHBondContact NE2-OD1 3.36Å; Q435-N439 PolarHBondContact O-N 3.39Å; Q435-N439 PolarHBondContact O-OD1 3.03Å; L436-N439 WeakPolarHBondContact O-CB 3.44Å; L436-N439 PolarHBondContact O-N 3.43Å; V437-N439 PolarHBondContact O-N 3.3Å; N439-M441 PolarHBondContact O-N 3.47Å; N439-H442 PolarHBondContact O-N 2.93Å; N439-H442 VanDerWaalsContact O-N 3.16Å
440	H	92.9	Very high	92.9	Very high	28 Å²	28	78 Å²	78	13%	0.13	37%	0.371	C	S	.	.	H	α-helix	trans	-67.3	-12.6	179.3	-76.1	-55.8	0	0	0	115.2	L398 L436 V437 M438 H442 H443 V448 A452	L398-H440 PolarHBondContact O-NE2 3.45Å; L436-H440 PolarHBondContact O-CD2 3.2Å; L436-H440 PolarHBondContact O-N 3.14Å; V437-H440 PolarHBondContact O-N 3.48Å; M438-H440 VanDerWaalsContact C-N 3.33Å; H440-H442 PolarHBondContact O-N 3.44Å; H440-H442 VanDerWaalsContact O-N 3.17Å; H440-H443 AromaticContact ND1-CD2 3.77Å; H440-H443 VanDerWaalsContact O-CB 3.23Å; H440-H443 WeakPolarHBondContact O-CB 2.98Å; H440-H443 PolarHBondContact O-N 2.76Å; H440-H443 VanDerWaalsContact O-N 3.13Å; H440-V448 HydrophobicContact CB-CG1 4.01Å; H440-A452 HydrophobicContact CB-CB 3.95Å
441	M	91.9	Very high	93	Very high	54 Å²	54	71.1 Å²	71.1	27%	0.266	34%	0.339	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.7	-19.8	169.7	-70.4	175.3	37.6	0	0	113.5	V437 M438 N439 R449 A452 L453 V456	V437-M441 PolarHBondContact O-N 2.93Å; M438-M441 WeakPolarHBondContact O-CB 3.15Å; M438-M441 PolarHBondContact O-N 3.46Å; N439-M441 PolarHBondContact O-N 3.47Å; M441-R449 WeakPolarHBondContact O-CD 3.42Å; M441-R449 VanDerWaalsContact O-CG 3.23Å; M441-R449 WeakPolarHBondContact O-CG 3.38Å; M441-A452 HydrophobicContact CG-CB 4.07Å; M441-L453 HydrophobicContact CE-CD1 3.86Å; M441-L453 HydrophobicContact SD-CD1 4.34Å; M441-V456 HydrophobicContact CG-CG2 4.29Å; M441-V456 HydrophobicContact SD-CB 3.97Å; M441-V456 HydrophobicContact SD-CG1 4.07Å; M441-V456 HydrophobicContact SD-CG2 3.67Å
442	H	91	Very high	93.1	Very high	155 Å²	155	69 Å²	69	72%	0.718	33%	0.328	S	S	*	.	T	Hydrogen-bonded Turn	trans	-106.9	11.8	179.4	-54.8	88.5	0	0	0	112.4	N439 H440	N439-H442 PolarHBondContact O-N 2.93Å; N439-H442 VanDerWaalsContact O-N 3.16Å; H440-H442 PolarHBondContact O-N 3.44Å; H440-H442 VanDerWaalsContact O-N 3.17Å
443	H	94.8	Very high	93.2	Very high	50 Å²	50	71 Å²	71	23%	0.231	33%	0.33	C	S	.	.			trans	-61.1	153.2	179.1	-166.6	-90.2	0	0	0	111.8	H440 D445 V448 R449	H440-H443 AromaticContact ND1-CD2 3.77Å; H440-H443 VanDerWaalsContact O-CB 3.23Å; H440-H443 WeakPolarHBondContact O-CB 2.98Å; H440-H443 PolarHBondContact O-N 2.76Å; H440-H443 VanDerWaalsContact O-N 3.13Å; H443-D445 WeakPolarHBondContact ND1-CB 3.49Å; H443-D445 PolarHBondContact ND1-N 3.25Å; H443-D445 VanDerWaalsContact ND1-N 3.11Å; H443-V448 HydrophobicContact CB-CB 4.02Å; H443-V448 HydrophobicContact CB-CG1 3.62Å; H443-R449 HydrophobicContact CB-CG 4.16Å; H443-R449 WeakPolarHBondContact O-CD 3.47Å; H443-R449 WeakPolarHBondContact O-CG 3.34Å; H443-R449 PolarHBondContact O-NE 3.26Å
444	E	93.8	Very high	93.2	Very high	181 Å²	181	72.8 Å²	72.8	85%	0.846	34%	0.34	S	S	*	.	S	Bend	trans	-66.1	-43.8	-178.3	-60.4	-173.9	166.1	0	0	111.3	R449	E444-R449 PolarHBondContact O-NH2 2.9Å
445	D	95.1	Very high	93.4	Very high	57 Å²	57	70.1 Å²	70.1	31%	0.305	33%	0.328	S	S	.	.	S	Bend	trans	-63.9	133.3	177.1	-175.2	-91.4	0	0	0	113.3	P404 H443 Q447 V448 R449	P404-D445 HydrophobicContact CB-CB 3.91Å; P404-D445 HydrophobicContact CG-CB 4.42Å; H443-D445 WeakPolarHBondContact ND1-CB 3.49Å; H443-D445 PolarHBondContact ND1-N 3.25Å; H443-D445 VanDerWaalsContact ND1-N 3.11Å; D445-Q447 WeakPolarHBondContact OD1-CA 3.24Å; D445-Q447 VanDerWaalsContact OD1-CB 3.31Å; D445-Q447 WeakPolarHBondContact OD1-CB 3.35Å; D445-Q447 PolarHBondContact OD1-N 3.48Å; D445-V448 HydrophobicContact CB-CB 4.26Å; D445-V448 HydrophobicContact CB-CG2 3.94Å; D445-V448 PolarHBondContact OD1-N 3.35Å; D445-R449 WeakPolarHBondContact O-CG 3.41Å; D445-R449 PolarHBondContact O-N 3.34Å; D445-R449 PolarHBondContact O-NE 3.5Å
446	Q	94.6	Very high	93.4	Very high	151 Å²	151	66 Å²	66	71%	0.706	31%	0.31	S	S	*	.	H	α-helix	trans	-70.4	-35.8	-177	-174.8	178.9	-3	0	0	113	Y450	Q446-Y450 VanDerWaalsContact O-CB 3.27Å; Q446-Y450 WeakPolarHBondContact O-CB 3.46Å; Q446-Y450 PolarHBondContact O-N 3.13Å
447	Q	92.9	Very high	93.2	Very high	108 Å²	108	68.1 Å²	68.1	51%	0.505	32%	0.319	S	S	.	.	H	α-helix	trans	-71.2	-39.5	-179.8	-62	-170.3	4.1	0	0	111.2	A408 D445 Y450 N451	A408-Q447 HydrophobicContact CB-CB 4.27Å; D445-Q447 WeakPolarHBondContact OD1-CA 3.24Å; D445-Q447 VanDerWaalsContact OD1-CB 3.31Å; D445-Q447 WeakPolarHBondContact OD1-CB 3.35Å; D445-Q447 PolarHBondContact OD1-N 3.48Å; Q447-Y450 PolarHBondContact O-N 3.17Å; Q447-N451 PolarHBondContact O-N 3Å; Q447-N451 PolarHBondContact O-ND2 3.15Å
448	V	95.4	Very high	93	Very high	0 Å²	0	69 Å²	69	0%	0	32%	0.323	C	S	.	.	H	α-helix	trans	-59.6	-51.6	174	179.4	0	0	0	0	110.1	P404 L407 A408 H440 H443 D445 Y450 N451 A452	P404-V448 HydrophobicContact CB-CG2 3.92Å; P404-V448 WeakPolarHBondContact O-CG2 3.2Å; L407-V448 HydrophobicContact CB-CG1 4.09Å; L407-V448 HydrophobicContact CB-CG2 3.89Å; A408-V448 HydrophobicContact CB-CG2 4.19Å; H440-V448 HydrophobicContact CB-CG1 4.01Å; H443-V448 HydrophobicContact CB-CB 4.02Å; H443-V448 HydrophobicContact CB-CG1 3.62Å; D445-V448 HydrophobicContact CB-CB 4.26Å; D445-V448 HydrophobicContact CB-CG2 3.94Å; D445-V448 PolarHBondContact OD1-N 3.35Å; V448-Y450 VanDerWaalsContact C-N 3.34Å; V448-Y450 PolarHBondContact O-N 3.41Å; V448-N451 PolarHBondContact O-N 2.9Å; V448-A452 WeakPolarHBondContact O-CB 3.37Å; V448-A452 PolarHBondContact O-N 3.41Å
449	R	96.1	Very high	92.7	Very high	109 Å²	109	65.7 Å²	65.7	41%	0.411	31%	0.307	S	S	.	.	H	α-helix	trans	-57.8	-45.2	178	-73.1	-171.4	-80.3	-179.5	-7.2	113	M441 H443 E444 D445 A452 L453	M441-R449 WeakPolarHBondContact O-CD 3.42Å; M441-R449 VanDerWaalsContact O-CG 3.23Å; M441-R449 WeakPolarHBondContact O-CG 3.38Å; H443-R449 HydrophobicContact CB-CG 4.16Å; H443-R449 WeakPolarHBondContact O-CD 3.47Å; H443-R449 WeakPolarHBondContact O-CG 3.34Å; H443-R449 PolarHBondContact O-NE 3.26Å; E444-R449 PolarHBondContact O-NH2 2.9Å; D445-R449 WeakPolarHBondContact O-CG 3.41Å; D445-R449 PolarHBondContact O-N 3.34Å; D445-R449 PolarHBondContact O-NE 3.5Å; R449-A452 PolarHBondContact O-N 3.14Å; R449-L453 VanDerWaalsContact O-CB 3.32Å; R449-L453 WeakPolarHBondContact O-CB 3.45Å; R449-L453 PolarHBondContact O-N 3.16Å
450	Y	94.6	Very high	92	Very high	143 Å²	143	66.7 Å²	66.7	56%	0.561	31%	0.31	S	S	*	.	H	α-helix	trans	-60.4	-50.8	-179.5	175.1	-101.7	0	0	0	111.5	Q446 Q447 V448 L453 L454	Q446-Y450 VanDerWaalsContact O-CB 3.27Å; Q446-Y450 WeakPolarHBondContact O-CB 3.46Å; Q446-Y450 PolarHBondContact O-N 3.13Å; Q447-Y450 PolarHBondContact O-N 3.17Å; V448-Y450 VanDerWaalsContact C-N 3.34Å; V448-Y450 PolarHBondContact O-N 3.41Å; Y450-L453 PolarHBondContact O-N 2.95Å; Y450-L454 HydrophobicContact CD1-CD1 4.09Å; Y450-L454 HydrophobicContact CE1-CD1 3.46Å; Y450-L454 VanDerWaalsContact CE1-CD1 3.46Å; Y450-L454 HydrophobicContact CE1-CG 4.42Å; Y450-L454 HydrophobicContact CE2-CD1 4.22Å; Y450-L454 HydrophobicContact CE2-CG 4.5Å; Y450-L454 WeakPolarHBondContact O-CG 3.32Å; Y450-L454 PolarHBondContact O-N 3.35Å; Y450-L454 VanDerWaalsContact O-N 3.07Å
451	N	95	Very high	90.7	Very high	12 Å²	12	68 Å²	68	6%	0.064	32%	0.32	C	S	.	.	H	α-helix	trans	-69.3	-37	-179.4	-72.6	-66	0	0	0	112.2	A408 A411 H412 Q447 V448 L454 A455	A408-N451 WeakPolarHBondContact O-CB 3.49Å; A411-N451 HydrophobicContact CB-CB 4.34Å; H412-N451 HydrophobicContact CB-CB 4.25Å; Q447-N451 PolarHBondContact O-N 3Å; Q447-N451 PolarHBondContact O-ND2 3.15Å; V448-N451 PolarHBondContact O-N 2.9Å; N451-L454 PolarHBondContact O-N 3.26Å; N451-A455 WeakPolarHBondContact O-CB 3.49Å; N451-A455 PolarHBondContact O-N 3.15Å
452	A	94	Very high	89.1	Confident	0 Å²	0	73.4 Å²	73.4	0%	0	34%	0.344	C	S	.	.	H	α-helix	trans	-61.4	-44.3	173.6	0	0	0	0	0	112.1	A411 V437 H440 M441 V448 R449 A455 V456	A411-A452 HydrophobicContact CB-CB 4.38Å; V437-A452 HydrophobicContact CG1-CB 4.08Å; V437-A452 WeakPolarHBondContact CG1-O 3.27Å; H440-A452 HydrophobicContact CB-CB 3.95Å; M441-A452 HydrophobicContact CG-CB 4.07Å; V448-A452 WeakPolarHBondContact O-CB 3.37Å; V448-A452 PolarHBondContact O-N 3.41Å; R449-A452 PolarHBondContact O-N 3.14Å; A452-A455 PolarHBondContact O-N 2.81Å; A452-V456 WeakPolarHBondContact O-CG2 3.43Å; A452-V456 PolarHBondContact O-N 3.36Å
453	L	93	Very high	87.2	Confident	75 Å²	75	71.2 Å²	71.2	39%	0.393	34%	0.337	S	S	.	.	H	α-helix	trans	-61.5	-46.4	176.5	-176.3	68.8	0	0	0	111.5	M441 R449 Y450 A455 V456 Q457	M441-L453 HydrophobicContact CE-CD1 3.86Å; M441-L453 HydrophobicContact SD-CD1 4.34Å; R449-L453 VanDerWaalsContact O-CB 3.32Å; R449-L453 WeakPolarHBondContact O-CB 3.45Å; R449-L453 PolarHBondContact O-N 3.16Å; Y450-L453 PolarHBondContact O-N 2.95Å; L453-A455 VanDerWaalsContact C-N 3.32Å; L453-A455 PolarHBondContact O-N 3.41Å; L453-V456 PolarHBondContact O-N 2.74Å; L453-Q457 VanDerWaalsContact O-CG 3.32Å; L453-Q457 WeakPolarHBondContact O-CG 3.36Å; L453-Q457 PolarHBondContact O-N 3.38Å
454	L	92.8	Very high	85.2	Confident	39 Å²	39	72.3 Å²	72.3	20%	0.204	34%	0.34	C	S	.	.	H	α-helix	trans	-61.2	-40.9	176.8	-71.6	-179	0	0	0	112.1	Y450 N451 Q457 K458	Y450-L454 HydrophobicContact CD1-CD1 4.09Å; Y450-L454 HydrophobicContact CE1-CD1 3.46Å; Y450-L454 VanDerWaalsContact CE1-CD1 3.46Å; Y450-L454 HydrophobicContact CE1-CG 4.42Å; Y450-L454 HydrophobicContact CE2-CD1 4.22Å; Y450-L454 HydrophobicContact CE2-CG 4.5Å; Y450-L454 WeakPolarHBondContact O-CG 3.32Å; Y450-L454 PolarHBondContact O-N 3.35Å; Y450-L454 VanDerWaalsContact O-N 3.07Å; N451-L454 PolarHBondContact O-N 3.26Å; L454-Q457 WeakPolarHBondContact O-CB 3.45Å; L454-Q457 PolarHBondContact O-N 3.34Å; L454-K458 VanDerWaalsContact O-CG 3.32Å; L454-K458 WeakPolarHBondContact O-CG 3.41Å; L454-K458 PolarHBondContact O-N 3.4Å
455	A	93.8	Very high	83.2	Confident	1 Å²	1	71.5 Å²	71.5	1%	0.008	34%	0.336	C	S	.	.	H	α-helix	trans	-65.8	-40.9	177.3	0	0	0	0	0	112	A411 V437 N451 A452 L453 K458 L459	A411-A455 WeakPolarHBondContact O-CB 3.46Å; V437-A455 HydrophobicContact CG1-CB 3.69Å; N451-A455 WeakPolarHBondContact O-CB 3.49Å; N451-A455 PolarHBondContact O-N 3.15Å; A452-A455 PolarHBondContact O-N 2.81Å; L453-A455 VanDerWaalsContact C-N 3.32Å; L453-A455 PolarHBondContact O-N 3.41Å; A455-K458 PolarHBondContact O-N 3.43Å; A455-L459 WeakPolarHBondContact O-CG 3.39Å; A455-L459 PolarHBondContact O-N 3.45Å
456	V	91.8	Very high	80.9	Confident	21 Å²	21	77.3 Å²	77.3	13%	0.127	36%	0.355	C	S	.	.	H	α-helix	trans	-64.2	-41.5	173.3	171.5	0	0	0	0	111.5	V437 M438 M441 A452 L453 K458 L459 M460	V437-V456 HydrophobicContact CB-CG2 4.47Å; V437-V456 HydrophobicContact CG1-CG2 3.85Å; M438-V456 HydrophobicContact CG-CG2 3.83Å; M441-V456 HydrophobicContact CG-CG2 4.29Å; M441-V456 HydrophobicContact SD-CB 3.97Å; M441-V456 HydrophobicContact SD-CG1 4.07Å; M441-V456 HydrophobicContact SD-CG2 3.67Å; A452-V456 WeakPolarHBondContact O-CG2 3.43Å; A452-V456 PolarHBondContact O-N 3.36Å; L453-V456 PolarHBondContact O-N 2.74Å; V456-K458 VanDerWaalsContact C-N 3.31Å; V456-K458 PolarHBondContact O-N 3.34Å; V456-L459 WeakPolarHBondContact O-CB 3.5Å; V456-L459 PolarHBondContact O-N 3.42Å; V456-L459 VanDerWaalsContact O-N 3.14Å; V456-M460 HydrophobicContact CG1-CG 4.04Å; V456-M460 WeakPolarHBondContact O-CB 3.47Å; V456-M460 VanDerWaalsContact O-CG 3.23Å; V456-M460 WeakPolarHBondContact O-CG 3.5Å; V456-M460 PolarHBondContact O-N 3.2Å
457	Q	88.2	Confident	78.7	Confident	81 Å²	81	73.5 Å²	73.5	38%	0.379	34%	0.339	S	S	.	.	H	α-helix	trans	-56.8	-46.5	174.3	-73.2	174.2	0.5	0	0	111.2	L453 L454 L459 M460 V461 W464	L453-Q457 VanDerWaalsContact O-CG 3.32Å; L453-Q457 WeakPolarHBondContact O-CG 3.36Å; L453-Q457 PolarHBondContact O-N 3.38Å; L454-Q457 WeakPolarHBondContact O-CB 3.45Å; L454-Q457 PolarHBondContact O-N 3.34Å; Q457-L459 VanDerWaalsContact C-N 3.33Å; Q457-L459 PolarHBondContact O-N 3.46Å; Q457-M460 PolarHBondContact O-N 3.38Å; Q457-V461 VanDerWaalsContact O-CG2 3.31Å; Q457-V461 WeakPolarHBondContact O-CG2 3.42Å; Q457-V461 PolarHBondContact O-N 3.39Å; Q457-V461 VanDerWaalsContact O-N 3.14Å; Q457-W464 HydrophobicContact CB-CZ3 4.43Å
458	K	88.9	Confident	76.6	Confident	19 Å²	19	70.1 Å²	70.1	8%	0.083	33%	0.333	C	S	.	.	H	α-helix	trans	-63.8	-34.6	176.4	-67.6	166.7	-178	173.3	0	112.8	G415 E416 L454 A455 V456 W464	G415-K458 WeakPolarHBondContact O-CD 3.45Å; E416-K458 IonicContact OE1-NZ 2.81Å; E416-K458 PolarHBondContact OE1-NZ 3.15Å; L454-K458 VanDerWaalsContact O-CG 3.32Å; L454-K458 WeakPolarHBondContact O-CG 3.41Å; L454-K458 PolarHBondContact O-N 3.4Å; A455-K458 PolarHBondContact O-N 3.43Å; V456-K458 VanDerWaalsContact C-N 3.31Å; V456-K458 PolarHBondContact O-N 3.34Å; K458-W464 HydrophobicContact CG-CD2 4.31Å; K458-W464 HydrophobicContact CG-CE3 3.96Å; K458-W464 HydrophobicContact CG-CH2 4.02Å; K458-W464 HydrophobicContact CG-CZ2 4.35Å; K458-W464 HydrophobicContact CG-CZ3 3.81Å
459	L	83.8	Confident	74.2	Confident	3 Å²	3	77.8 Å²	77.8	2%	0.016	37%	0.366	C	S	.	.	H	α-helix	trans	-70.3	-31.7	175	-81	161.5	0	0	0	113.5	V418 K425 I428 A455 V456 Q457	V418-L459 HydrophobicContact CB-CD2 4.35Å; V418-L459 HydrophobicContact CG1-CD2 4.02Å; V418-L459 HydrophobicContact CG1-CG 4.38Å; V418-L459 HydrophobicContact CG2-CD2 3.55Å; V418-L459 HydrophobicContact CG2-CG 4.15Å; K425-L459 VanDerWaalsContact CD-O 3.3Å; K425-L459 WeakPolarHBondContact CD-O 3.44Å; K425-L459 WeakPolarHBondContact CE-O 3.4Å; K425-L459 HydrophobicContact CG-CD2 4.29Å; K425-L459 PolarHBondContact NZ-O 3.34Å; I428-L459 HydrophobicContact CB-CD2 4.46Å; I428-L459 HydrophobicContact CG2-CD2 4.22Å; A455-L459 WeakPolarHBondContact O-CG 3.39Å; A455-L459 PolarHBondContact O-N 3.45Å; V456-L459 WeakPolarHBondContact O-CB 3.5Å; V456-L459 PolarHBondContact O-N 3.42Å; V456-L459 VanDerWaalsContact O-N 3.14Å; Q457-L459 VanDerWaalsContact C-N 3.33Å; Q457-L459 PolarHBondContact O-N 3.46Å
460	M	77.8	Confident	71.7	Confident	114 Å²	114	78.2 Å²	78.2	56%	0.562	37%	0.373	S	S	*	.	H	α-helix	trans	-87.5	-27	-174.1	-69.2	-63.5	-73.3	0	0	113.1	V456 Q457	V456-M460 HydrophobicContact CG1-CG 4.04Å; V456-M460 WeakPolarHBondContact O-CB 3.47Å; V456-M460 VanDerWaalsContact O-CG 3.23Å; V456-M460 WeakPolarHBondContact O-CG 3.5Å; V456-M460 PolarHBondContact O-N 3.2Å; Q457-M460 PolarHBondContact O-N 3.38Å
461	V	66.4	Low	69.3	Low	54 Å²	54	77.2 Å²	77.2	33%	0.327	38%	0.376	S	S	.	.			trans	-91.5	124.8	-175.2	177.3	0	0	0	0	111.3	Q457 N463 L467	Q457-V461 VanDerWaalsContact O-CG2 3.31Å; Q457-V461 WeakPolarHBondContact O-CG2 3.42Å; Q457-V461 PolarHBondContact O-N 3.39Å; Q457-V461 VanDerWaalsContact O-N 3.14Å; V461-N463 VanDerWaalsContact C-N 3.3Å; V461-N463 PolarHBondContact O-N 3.35Å; V461-L467 HydrophobicContact CG1-CD1 3.87Å; V461-L467 HydrophobicContact CG2-CD1 4.21Å
462	H	57.2	Low	66.8	Low	169 Å²	169	84.2 Å²	84.2	78%	0.782	41%	0.409	S	S	*	.	S	Bend	trans	-77.4	-8.5	178.8	-88.3	-78.7	0	0	0	114.4
463	N	50.8	Low	64.4	Low	108 Å²	108	88.5 Å²	88.5	58%	0.578	44%	0.439	S	S	*	.			trans	-153.7	89.8	-179.3	-119	4.2	0	0	0	111.9	V461 E465	V461-N463 VanDerWaalsContact C-N 3.3Å; V461-N463 PolarHBondContact O-N 3.35Å; N463-E465 PolarHBondContact O-N 2.94Å
464	W	52.9	Low	61.8	Low	74 Å²	74	92.2 Å²	92.2	28%	0.28	45%	0.454	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.8	-27.7	-176.5	-176.8	-101.2	0	0	0	114	Q457 K458 Y466 L467	Q457-W464 HydrophobicContact CB-CZ3 4.43Å; K458-W464 HydrophobicContact CG-CD2 4.31Å; K458-W464 HydrophobicContact CG-CE3 3.96Å; K458-W464 HydrophobicContact CG-CH2 4.02Å; K458-W464 HydrophobicContact CG-CZ2 4.35Å; K458-W464 HydrophobicContact CG-CZ3 3.81Å; W464-Y466 PolarHBondContact O-N 3.47Å; W464-Y466 VanDerWaalsContact O-N 3.08Å; W464-L467 PolarHBondContact O-N 3.2Å
465	E	52.5	Low	59.1	Low	163 Å²	163	98.1 Å²	98.1	76%	0.762	48%	0.481	S	S	*	.	H	α-helix	trans	-60.1	-21.8	-178.8	-70.5	-173.5	158	0	0	114.2	N463	N463-E465 PolarHBondContact O-N 2.94Å
466	Y	46.9	Very low	56.4	Low	179 Å²	179	103.7 Å²	103.7	70%	0.702	52%	0.517	S	S	*	.	H	α-helix	trans	-81.9	-29.1	-177.5	-113.3	-95.6	0	0	0	113.7	W464	W464-Y466 PolarHBondContact O-N 3.47Å; W464-Y466 VanDerWaalsContact O-N 3.08Å
467	L	47.6	Very low	53.9	Low	72 Å²	72	111.8 Å²	111.8	38%	0.377	55%	0.553	S	S	.	*	H	α-helix	trans	-81.9	-36.1	-176.6	-90.1	133	0	0	0	113	V461 W464 K469 Q470 L471	V461-L467 HydrophobicContact CG1-CD1 3.87Å; V461-L467 HydrophobicContact CG2-CD1 4.21Å; W464-L467 PolarHBondContact O-N 3.2Å; L467-K469 VanDerWaalsContact C-N 3.27Å; L467-K469 PolarHBondContact O-N 2.79Å; L467-Q470 PolarHBondContact O-N 3.14Å; L467-L471 PolarHBondContact O-N 3.29Å
468	G	48.7	Very low	51.4	Low	36 Å²	36	114.6 Å²	114.6	37%	0.371	58%	0.576	S	S	.	*	H	α-helix	trans	-63.5	-31.4	178.5	0	0	0	0	0	113.5	Q472	G468-Q472 PolarHBondContact O-N 3.35Å
469	K	46.3	Very low	48.9	Very low	162 Å²	162	118.1 Å²	118.1	70%	0.704	61%	0.609	S	S	*	*	H	α-helix	trans	-73.3	-30.7	176.2	-77.4	-177.3	176.8	175.7	0	113.3	L467 S473	L467-K469 VanDerWaalsContact C-N 3.27Å; L467-K469 PolarHBondContact O-N 2.79Å; K469-S473 PolarHBondContact O-N 3.39Å; K469-S473 PolarHBondContact O-OG 2.95Å
470	Q	42.2	Very low	46.8	Very low	117 Å²	117	123.1 Å²	123.1	55%	0.547	65%	0.65	S	S	.	*	H	α-helix	trans	-73.4	-38	177.4	-75.9	-178.7	-38.3	0	0	112.1	L467 Q472 S473 E474	L467-Q470 PolarHBondContact O-N 3.14Å; Q470-Q472 PolarHBondContact O-N 3.27Å; Q470-S473 WeakPolarHBondContact CA-OG 3.4Å; Q470-S473 PolarHBondContact O-N 2.91Å; Q470-S473 PolarHBondContact O-OG 3.04Å; Q470-E474 PolarHBondContact O-N 3.42Å
471	L	43.9	Very low	44.8	Very low	122 Å²	122	122.1 Å²	122.1	64%	0.639	66%	0.66	S	S	*	*	H	α-helix	trans	-69.6	-30.3	177.7	-78.8	156.3	0	0	0	113.4	L467	L467-L471 PolarHBondContact O-N 3.29Å
472	Q	43.8	Very low	43.4	Very low	159 Å²	159	131.5 Å²	131.5	74%	0.743	69%	0.69	S	S	*	*	H	α-helix	trans	-75.4	-26.4	172.8	-76.3	-178.4	-8.5	0	0	113	G468 Q470 E474	G468-Q472 PolarHBondContact O-N 3.35Å; Q470-Q472 PolarHBondContact O-N 3.27Å; Q472-E474 VanDerWaalsContact C-N 3.32Å
473	S	42.5	Very low	42.3	Very low	91 Å²	91	132.7 Å²	132.7	64%	0.636	72%	0.717	S	S	*	*	H	α-helix	trans	-78.8	-10.4	177	55.8	0	0	0	0	114.7	K469 Q470	K469-S473 PolarHBondContact O-N 3.39Å; K469-S473 PolarHBondContact O-OG 2.95Å; Q470-S473 WeakPolarHBondContact CA-OG 3.4Å; Q470-S473 PolarHBondContact O-N 2.91Å; Q470-S473 PolarHBondContact O-OG 3.04Å
474	E	39.2	Very low	41.9	Very low	153 Å²	153	133.9 Å²	133.9	72%	0.715	72%	0.724	S	S	*	*	T	Hydrogen-bonded Turn	trans	-100.3	11	-178.6	-73.1	-173.4	162.9	0	0	114.4	Q470 Q472 P476	Q470-E474 PolarHBondContact O-N 3.42Å; Q472-E474 VanDerWaalsContact C-N 3.32Å; E474-P476 WeakPolarHBondContact O-CD 2.89Å
475	Q	35.4	Very low	41.3	Very low	162 Å²	162	137.1 Å²	137.1	76%	0.757	75%	0.747	S	S	*	*	S	Bend	trans	-74.8	122	166.9	-76.1	-172.4	-12.3	0	0	110.2	Q477	Q475-Q477 PolarHBondContact O-N 3.3Å
476	P	37.1	Very low	40.7	Very low	118 Å²	118	135.6 Å²	135.6	77%	0.766	75%	0.747	S	S	*	*			trans	-66.3	125.9	177.4	-13.9	27.5	0	0	0	110	E474 T478	E474-P476 WeakPolarHBondContact O-CD 2.89Å; P476-T478 PolarHBondContact O-N 2.98Å
477	Q	39.2	Very low	40.3	Very low	192 Å²	192	133.1 Å²	133.1	90%	0.897	75%	0.749	S	S	*	*			trans	-57.8	105.7	161.7	-73.4	179	-10.3	0	0	108	Q475 A479	Q475-Q477 PolarHBondContact O-N 3.3Å; Q477-A479 PolarHBondContact O-N 2.94Å
478	T	36.2	Very low	39.8	Very low	140 Å²	140	136.9 Å²	136.9	86%	0.859	77%	0.772	S	S	*	*			trans	-61.8	103.8	167	40.6	0	0	0	0	108.1	P476 A480	P476-T478 PolarHBondContact O-N 2.98Å; T478-A480 PolarHBondContact O-N 3.39Å
479	A	36.1	Very low	39.3	Very low	93 Å²	93	143.6 Å²	143.6	77%	0.769	80%	0.799	S	S	*	*			trans	-57.2	121.7	174.7	0	0	0	0	0	110.3	Q477 A481	Q477-A479 PolarHBondContact O-N 2.94Å; A479-A481 PolarHBondContact O-N 3.3Å
480	A	40.4	Very low	38.8	Very low	107 Å²	107	142.3 Å²	142.3	88%	0.884	81%	0.806	S	S	*	*			trans	-65.4	118	157.6	0	0	0	0	0	108.8	T478	T478-A480 PolarHBondContact O-N 3.39Å
481	A	34.9	Very low	38.5	Very low	93 Å²	93	144.2 Å²	144.2	77%	0.769	83%	0.826	S	S	*	*			trans	-154.2	102.1	160.5	0	0	0	0	0	111.3	A479	A479-A481 PolarHBondContact O-N 3.3Å
482	R	36.9	Very low	38	Very low	251 Å²	251	146.1 Å²	146.1	95%	0.947	84%	0.842	S	S	*	*			trans	1.5	126.6	149.1	-66.1	173.2	174.1	173.9	-2.7	118
483	S	34.8	Very low	37.5	Very low	194 Å²	194	144.9 Å²	144.9	100%	1.357	85%	0.851	S	S	*	*				-147.9	0	121	61.7	0	0	0	0	109

Retrieved 483 of 483 residues in 859 ms (Link to these results)

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