A0A096NFR2_PAPAN Loading...

Y+L amino acid transporter 2

AlphaFold DB (A0A663DC92), UniProt , Accession A0A096NFR2, Species PAPAN (Papio anubis, Olive baboon), Gene SLC7A6, Length 515 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33	Very low	31.2	Very low	229 Å²	229	158.7 Å²	158.7	100%	1.128	85%	0.853	S	S	*	*				0	82.8	0	-72.6	173	167.9	0	0	105.9
2	E	28.2	Very low	30.4	Very low	195 Å²	195	158 Å²	158	91%	0.911	86%	0.859	S	S	*	*				71.8	132.2	93.1	-81.9	180	140.7	0	0	112
3	A	28.7	Very low	30.1	Very low	88 Å²	88	162.2 Å²	162.2	73%	0.727	86%	0.857	S	S	*	*			cis	-161.5	137.4	7.2	0	0	0	0	0	108.8
4	R	27.4	Very low	29.6	Very low	244 Å²	244	163.4 Å²	163.4	92%	0.921	86%	0.855	S	S	*	*				45.6	120.7	102.5	-77.7	-175.4	176.8	177.3	-0.3	115.8
5	E	33.6	Very low	29.5	Very low	188 Å²	188	163 Å²	163	88%	0.879	85%	0.853	S	S	*	*				-154.1	170	75.3	-105.3	-163.5	173.3	0	0	114.3
6	P	39.5	Very low	29.3	Very low	122 Å²	122	161 Å²	161	79%	0.792	85%	0.849	S	S	*	*				-132.7	170.1	-123	40.6	-22.5	0	0	0	118
7	G	25.9	Very low	29.4	Very low	84 Å²	84	157.8 Å²	157.8	87%	0.866	84%	0.84	S	S	*	*			trans	158.2	82.1	159.6	0	0	0	0	0	117.4
8	R	25.3	Very low	29.2	Very low	243 Å²	243	157.1 Å²	157.1	92%	0.917	84%	0.836	S	S	*	*			trans	-66.7	-179.2	179.2	-85.7	-178.7	-176.3	-179.7	0.4	116.3
9	P	30.7	Very low	29.3	Very low	115 Å²	115	156.1 Å²	156.1	75%	0.747	84%	0.837	S	S	*	*			cis	-138.9	173.3	-29.7	34.4	-14	0	0	0	115.6
10	T	24.5	Very low	29.1	Very low	131 Å²	131	154.1 Å²	154.1	80%	0.804	84%	0.835	S	S	*	*			trans	-79.8	-176.4	160.9	43.7	0	0	0	0	112.8
11	P	46.3	Very low	29	Very low	107 Å²	107	156.3 Å²	156.3	70%	0.695	84%	0.841	S	S	*	*				-131.9	167.7	-63	39.1	-22.6	0	0	0	112.8
12	T	22.3	Very low	28.6	Very low	150 Å²	150	150.2 Å²	150.2	92%	0.92	82%	0.82	S	S	*	*			trans	-165	137.8	152.1	-8.9	0	0	0	0	113.1
13	Y	25.9	Very low	28.5	Very low	213 Å²	213	149.8 Å²	149.8	84%	0.835	82%	0.818	S	S	*	*			trans	-81.4	155.9	178.7	-79.9	-95.5	0	0	0	112.9
14	H	23.5	Very low	28.6	Very low	179 Å²	179	152.5 Å²	152.5	83%	0.829	83%	0.826	S	S	*	*				-178.5	107.4	126.7	-90.3	-64.3	0	0	0	113.2
15	L	27.6	Very low	28.6	Very low	157 Å²	157	149.7 Å²	149.7	82%	0.822	82%	0.823	S	S	*	*			trans	41.9	153.5	135.6	-79.9	158.8	0	0	0	126.3
16	V	26.2	Very low	28.6	Very low	131 Å²	131	150 Å²	150	79%	0.794	82%	0.824	S	S	*	*			trans	91.8	147.8	160.3	-116.2	0	0	0	0	119.6
17	P	32	Very low	28	Very low	107 Å²	107	151.4 Å²	151.4	70%	0.695	83%	0.825	S	S	*	*				-129.6	-161.8	-104.9	42.4	-21.6	0	0	0	112.8
18	N	25.9	Very low	28.7	Very low	144 Å²	144	154.1 Å²	154.1	77%	0.77	82%	0.824	S	S	*	*			trans	90.7	94.3	176.9	-72.9	-6.8	0	0	0	115.7
19	T	29.3	Very low	29	Very low	139 Å²	139	147.5 Å²	147.5	85%	0.853	82%	0.816	S	S	*	*				163.1	125.4	114.7	32.6	0	0	0	0	108.4
20	S	25.4	Very low	29	Very low	115 Å²	115	146.9 Å²	146.9	80%	0.804	81%	0.814	S	S	*	*			trans	-153.2	116.4	155.7	-41.3	0	0	0	0	108.9
21	Q	28.3	Very low	29.4	Very low	202 Å²	202	146 Å²	146	94%	0.944	81%	0.81	S	S	*	*			trans	-56.5	131.9	163.2	-67.5	161.1	-35.9	0	0	109.1
22	S	24.2	Very low	28.7	Very low	100 Å²	100	146.5 Å²	146.5	70%	0.699	81%	0.814	S	S	*	*			trans	-131.7	110.6	163.8	52.3	0	0	0	0	108.6
23	Q	25.4	Very low	29.2	Very low	187 Å²	187	148.6 Å²	148.6	87%	0.874	81%	0.813	S	S	*	*			trans	62.6	113.7	135	-66.9	176.7	-32.5	0	0	118.1	E25	Q23-E25 PolarHBondContact O-N 3.5Å
24	V	31.2	Very low	29.4	Very low	145 Å²	145	149.9 Å²	149.9	88%	0.879	82%	0.817	S	S	*	*			trans	-60.7	109.8	165.6	177.6	0	0	0	0	108.9
25	E	27.6	Very low	29.7	Very low	185 Å²	185	145.8 Å²	145.8	86%	0.864	81%	0.808	S	S	*	*			trans	-116.1	130.9	154.5	-89.8	-178.8	160.5	0	0	107.4	Q23 D27	Q23-E25 PolarHBondContact O-N 3.5Å; E25-D27 PolarHBondContact O-N 3.36Å; E25-D27 VanDerWaalsContact O-N 3.16Å
26	E	33.7	Very low	29.9	Very low	195 Å²	195	143 Å²	143	91%	0.911	80%	0.802	S	S	*	*			trans	-61.7	108.5	-179.1	-72.3	174.4	141.1	0	0	110.5
27	D	27.4	Very low	30.2	Very low	150 Å²	150	145 Å²	145	80%	0.802	80%	0.803	S	S	*	*			trans	-97.6	122.5	164.8	-148.7	-4.1	0	0	0	108.7	E25 S29	E25-D27 PolarHBondContact O-N 3.36Å; E25-D27 VanDerWaalsContact O-N 3.16Å; D27-S29 PolarHBondContact O-N 2.93Å
28	V	39.2	Very low	30.2	Very low	141 Å²	141	143.5 Å²	143.5	86%	0.855	79%	0.794	S	S	*	*			trans	-66.8	84.1	177	178.1	0	0	0	0	107.6	S30	V28-S30 PolarHBondContact O-N 3.45Å
29	S	32	Very low	30.5	Very low	105 Å²	105	145.9 Å²	145.9	73%	0.734	80%	0.803	S	S	*	*			trans	-73.9	116.8	174	49.4	0	0	0	0	109.4	D27	D27-S29 PolarHBondContact O-N 2.93Å
30	S	30.8	Very low	31.2	Very low	101 Å²	101	146.3 Å²	146.3	71%	0.706	80%	0.796	S	S	*	*			trans	-38.6	142.9	159.3	36	0	0	0	0	111.3	V28	V28-S30 PolarHBondContact O-N 3.45Å
31	P	33.8	Very low	32.6	Very low	112 Å²	112	145.1 Å²	145.1	73%	0.727	78%	0.779	S	S	*	*			trans	-56.7	142.1	176.8	24.4	-31.4	0	0	0	108.6	Q33	P31-Q33 PolarHBondContact O-N 3.1Å
32	P	32.1	Very low	34.3	Very low	119 Å²	119	143 Å²	143	77%	0.773	77%	0.767	S	S	*	*			trans	-55.7	119	-178.5	22.9	-30.9	0	0	0	107.3	R34	P32-R34 PolarHBondContact O-N 3.25Å
33	Q	31.2	Very low	36.7	Very low	194 Å²	194	144.3 Å²	144.3	91%	0.907	76%	0.76	S	S	*	*			trans	-53.9	101.8	163.4	-88.9	175.9	-29.1	0	0	105.2	P31 S35	P31-Q33 PolarHBondContact O-N 3.1Å; Q33-S35 PolarHBondContact O-N 3.19Å
34	R	30.4	Very low	39.2	Very low	240 Å²	240	141.3 Å²	141.3	91%	0.906	75%	0.746	S	S	*	*			trans	-55.7	102.9	158.2	-84.4	-177.2	178.3	175.5	-0.4	103.6	P32 S36	P32-R34 PolarHBondContact O-N 3.25Å; R34-S36 VanDerWaalsContact C-N 3.34Å; R34-S36 PolarHBondContact O-N 2.89Å
35	S	30.4	Very low	41.5	Very low	93 Å²	93	135.3 Å²	135.3	65%	0.65	71%	0.709	S	S	*	*			trans	-47.8	112.3	158.8	46.8	0	0	0	0	104.7	Q33 E37	Q33-S35 PolarHBondContact O-N 3.19Å; S35-E37 PolarHBondContact O-N 3.36Å
36	S	32	Very low	44.4	Very low	99 Å²	99	128.4 Å²	128.4	69%	0.692	68%	0.681	S	S	*	*			trans	-62.5	86.9	168.3	58.5	0	0	0	0	105	R34 S38	R34-S36 VanDerWaalsContact C-N 3.34Å; R34-S36 PolarHBondContact O-N 2.89Å; S36-S38 PolarHBondContact O-N 3.39Å
37	E	31.6	Very low	47	Very low	173 Å²	173	121.4 Å²	121.4	81%	0.808	65%	0.65	S	S	*	*			trans	-63.6	89.1	166.4	-77.6	-170.4	162	0	0	104.8	S35 M39	S35-E37 PolarHBondContact O-N 3.36Å; E37-M39 PolarHBondContact O-N 3.16Å; E37-M39 VanDerWaalsContact O-N 3.16Å
38	S	31.7	Very low	49.6	Very low	74 Å²	74	120.9 Å²	120.9	52%	0.517	65%	0.646	S	S	.	*			trans	-47.9	123.7	165.3	52.4	0	0	0	0	106.4	S36 Q40	S36-S38 PolarHBondContact O-N 3.39Å; S38-Q40 PolarHBondContact O-N 2.9Å; S38-Q40 PolarHBondContact OG-NE2 3.46Å
39	M	33.4	Very low	51.7	Low	194 Å²	194	118.2 Å²	118.2	96%	0.956	63%	0.627	S	S	*	*			trans	-72.3	78	-179.3	-161.9	179.9	-63	0	0	108	E37	E37-M39 PolarHBondContact O-N 3.16Å; E37-M39 VanDerWaalsContact O-N 3.16Å
40	Q	43.7	Very low	54.1	Low	149 Å²	149	113.4 Å²	113.4	70%	0.696	59%	0.594	S	S	*	*	P	Polyproline II helix	trans	-70.5	137.1	178.3	-66.3	-176.3	3.2	0	0	109.1	S38 K42	S38-Q40 PolarHBondContact O-N 2.9Å; S38-Q40 PolarHBondContact OG-NE2 3.46Å; Q40-K42 PolarHBondContact O-N 2.86Å
41	L	54.4	Low	56.8	Low	89 Å²	89	109.6 Å²	109.6	47%	0.466	57%	0.566	S	S	.	*	P	Polyproline II helix	trans	-53.3	127.6	171.6	-74.2	172.1	0	0	0	109.1	K43 E258 E259	L41-K43 PolarHBondContact O-N 3.48Å; L41-E258 HydrophobicContact CD1-CB 4.33Å; L41-E259 HydrophobicContact CB-CG 4.11Å; L41-E259 HydrophobicContact CD1-CG 4.16Å
42	K	64.3	Low	59.1	Low	157 Å²	157	106.6 Å²	106.6	68%	0.683	55%	0.548	S	S	*	.	P	Polyproline II helix	trans	-67.5	129.3	-177.7	-69.4	-174.5	178.7	-179.9	0	109.5	Q40 E44	Q40-K42 PolarHBondContact O-N 2.86Å; K42-E44 VanDerWaalsContact C-N 3.32Å; K42-E44 HydrophobicContact CB-CG 3.78Å; K42-E44 VanDerWaalsContact CD-OE1 3.3Å; K42-E44 WeakPolarHBondContact CD-OE1 3.35Å; K42-E44 PolarHBondContact O-N 3.27Å
43	K	74.8	Confident	61.4	Low	128 Å²	128	103.1 Å²	103.1	56%	0.557	52%	0.523	S	S	*	.			trans	-73.3	83	174.6	-65.4	-177.3	-177.9	178.1	0	110.5	L41 E258 E259 K261	L41-K43 PolarHBondContact O-N 3.48Å; K43-E258 WeakPolarHBondContact CG-O 3.27Å; K43-E259 CarbonylContact C-O 3.59Å; K43-E259 VanDerWaalsContact CA-O 3.31Å; K43-E259 WeakPolarHBondContact CA-O 3.26Å; K43-K261 HydrophobicContact CB-CG 4.33Å; K43-K261 WeakPolarHBondContact O-CE 3.3Å; K43-K261 VanDerWaalsContact O-CG 3.24Å; K43-K261 WeakPolarHBondContact O-CG 3.17Å
44	E	78.6	Confident	63.9	Low	124 Å²	124	93.9 Å²	93.9	58%	0.579	48%	0.479	S	S	*	.			trans	-106.4	-20.9	-174.8	-65.9	-171.4	176	0	0	113.5	K42 S46 E259	K42-E44 VanDerWaalsContact C-N 3.32Å; K42-E44 HydrophobicContact CB-CG 3.78Å; K42-E44 VanDerWaalsContact CD-OE1 3.3Å; K42-E44 WeakPolarHBondContact CD-OE1 3.35Å; K42-E44 PolarHBondContact O-N 3.27Å; E44-S46 PolarHBondContact O-N 3.12Å; E44-E259 PolarHBondContact N-O 2.9Å
45	I	79.5	Confident	66.5	Low	20 Å²	20	83.4 Å²	83.4	10%	0.103	44%	0.442	C	S	.	.	B	Isolated β-bridge	trans	-77	112.9	-173.9	-55.4	179.4	0	0	0	110.4	N49 V256 E259 I260 K261	I45-N49 HydrophobicContact CG2-CB 3.95Å; I45-V256 HydrophobicContact CD1-CB 3.92Å; I45-V256 HydrophobicContact CD1-CG2 3.8Å; I45-E259 HydrophobicContact CD1-CB 3.7Å; I45-E259 HydrophobicContact CG1-CB 4.04Å; I45-E259 PolarHBondContact N-O 2.94Å; I45-I260 HydrophobicContact CB-CG1 4.23Å; I45-I260 HydrophobicContact CG2-CG1 4.24Å; I45-K261 PolarHBondContact O-N 2.65Å
46	S	88.1	Confident	68.8	Low	39 Å²	39	79.2 Å²	79.2	27%	0.273	41%	0.414	S	S	.	.			trans	-80	169.9	174.1	80.5	0	0	0	0	112.1	E44 L48 N49 G50	E44-S46 PolarHBondContact O-N 3.12Å; S46-L48 PolarHBondContact O-N 3.36Å; S46-N49 PolarHBondContact O-N 2.88Å; S46-N49 PolarHBondContact OG-N 3.48Å; S46-N49 PolarHBondContact OG-OD1 3.38Å; S46-N49 VanDerWaalsContact OG-OD1 3.1Å; S46-G50 PolarHBondContact O-N 3.46Å
47	L	86.8	Confident	71	Confident	49 Å²	49	76.8 Å²	76.8	26%	0.257	39%	0.393	S	S	.	.	H	α-helix	trans	-57.3	-46.2	175.2	176.7	62.2	0	0	0	112.5	N49 G50 V51 N266 L269 A270	L47-N49 VanDerWaalsContact C-N 3.33Å; L47-N49 PolarHBondContact O-N 3.44Å; L47-G50 PolarHBondContact O-N 3.09Å; L47-V51 WeakPolarHBondContact O-CG2 3.49Å; L47-V51 PolarHBondContact O-N 3.49Å; L47-N266 HydrophobicContact CB-CB 4.47Å; L47-N266 HydrophobicContact CD1-CB 4.31Å; L47-N266 WeakPolarHBondContact CD1-O 3.43Å; L47-L269 HydrophobicContact CD1-CB 3.69Å; L47-L269 HydrophobicContact CD2-CB 4.44Å; L47-L269 HydrophobicContact CD2-CD1 4.37Å; L47-A270 HydrophobicContact CD1-CB 4.01Å
48	L	84	Confident	73.6	Confident	138 Å²	138	68.8 Å²	68.8	72%	0.723	36%	0.356	S	S	*	.	H	α-helix	trans	-65.4	-38.9	179.1	-71.3	174.6	0	0	0	111.5	S46 G50 V51 S52	S46-L48 PolarHBondContact O-N 3.36Å; L48-G50 VanDerWaalsContact C-N 3.29Å; L48-G50 PolarHBondContact O-N 2.85Å; L48-V51 PolarHBondContact O-N 2.96Å; L48-S52 WeakPolarHBondContact O-CB 3.29Å; L48-S52 PolarHBondContact O-N 3.06Å
49	N	81.4	Confident	76	Confident	86 Å²	86	65.3 Å²	65.3	46%	0.46	33%	0.332	S	S	.	.	H	α-helix	trans	-62.7	-40.9	174.1	-61.5	4.2	0	0	0	110.2	I45 S46 L47 S52 L53	I45-N49 HydrophobicContact CG2-CB 3.95Å; S46-N49 PolarHBondContact O-N 2.88Å; S46-N49 PolarHBondContact OG-N 3.48Å; S46-N49 PolarHBondContact OG-OD1 3.38Å; S46-N49 VanDerWaalsContact OG-OD1 3.1Å; L47-N49 VanDerWaalsContact C-N 3.33Å; L47-N49 PolarHBondContact O-N 3.44Å; N49-S52 PolarHBondContact O-N 3.21Å; N49-L53 WeakPolarHBondContact O-CB 3.36Å; N49-L53 PolarHBondContact O-N 2.87Å
50	G	83.4	Confident	78.2	Confident	3 Å²	3	56.5 Å²	56.5	3%	0.031	29%	0.29	C	S	.	.	H	α-helix	trans	-62.3	-45.6	175.4	0	0	0	0	0	113.1	S46 L47 L48 L53 V54	S46-G50 PolarHBondContact O-N 3.46Å; L47-G50 PolarHBondContact O-N 3.09Å; L48-G50 VanDerWaalsContact C-N 3.29Å; L48-G50 PolarHBondContact O-N 2.85Å; G50-L53 PolarHBondContact O-N 3.32Å; G50-V54 WeakPolarHBondContact O-CG2 3.39Å; G50-V54 PolarHBondContact O-N 2.8Å
51	V	86.9	Confident	79.8	Confident	21 Å²	21	49.8 Å²	49.8	13%	0.127	26%	0.26	C	S	.	.	H	α-helix	trans	-61.2	-48.1	174.7	173.9	0	0	0	0	110.5	L47 L48 L53 V54 V55 A270 I273	L47-V51 WeakPolarHBondContact O-CG2 3.49Å; L47-V51 PolarHBondContact O-N 3.49Å; L48-V51 PolarHBondContact O-N 2.96Å; V51-L53 VanDerWaalsContact C-N 3.28Å; V51-L53 PolarHBondContact O-N 3.44Å; V51-V54 PolarHBondContact O-N 2.88Å; V51-V55 HydrophobicContact CG1-CG2 4.15Å; V51-V55 WeakPolarHBondContact O-CB 3.38Å; V51-V55 VanDerWaalsContact O-CG2 3.28Å; V51-V55 WeakPolarHBondContact O-CG2 3.31Å; V51-V55 PolarHBondContact O-N 3.45Å; V51-A270 HydrophobicContact CG2-CB 4.16Å; V51-I273 HydrophobicContact CG1-CG2 4.12Å; V51-I273 HydrophobicContact CG2-CB 4.19Å; V51-I273 HydrophobicContact CG2-CD1 4.46Å; V51-I273 HydrophobicContact CG2-CG2 4.18Å
52	S	82.1	Confident	81.4	Confident	49 Å²	49	45.8 Å²	45.8	34%	0.343	24%	0.24	S	C	.	.	H	α-helix	trans	-61	-37.5	178.6	-170.9	0	0	0	0	112.2	L48 N49 G56	L48-S52 WeakPolarHBondContact O-CB 3.29Å; L48-S52 PolarHBondContact O-N 3.06Å; N49-S52 PolarHBondContact O-N 3.21Å; S52-G56 WeakPolarHBondContact O-CA 3.27Å; S52-G56 PolarHBondContact O-N 2.69Å
53	L	79.9	Confident	82.7	Confident	46 Å²	46	38.3 Å²	38.3	24%	0.241	21%	0.207	C	C	.	.	H	α-helix	trans	-67.2	-46.4	177.2	-174.2	159.1	0	0	0	111.1	N49 G50 V51 G56 N57 T252 L253 V256	N49-L53 WeakPolarHBondContact O-CB 3.36Å; N49-L53 PolarHBondContact O-N 2.87Å; G50-L53 PolarHBondContact O-N 3.32Å; V51-L53 VanDerWaalsContact C-N 3.28Å; V51-L53 PolarHBondContact O-N 3.44Å; L53-G56 PolarHBondContact O-N 2.75Å; L53-N57 WeakPolarHBondContact O-CB 3.28Å; L53-N57 VanDerWaalsContact O-CG 3.28Å; L53-N57 PolarHBondContact O-N 3.49Å; L53-T252 HydrophobicContact CD2-CG2 4.02Å; L53-L253 HydrophobicContact CD2-CD1 4.37Å; L53-V256 HydrophobicContact CD1-CG2 4.29Å
54	V	84.1	Confident	83.4	Confident	0 Å²	0	32.3 Å²	32.3	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-66.2	-50.5	178.8	176	0	0	0	0	111	G50 V51 G56 N57 M58 W250 L253 S274	G50-V54 WeakPolarHBondContact O-CG2 3.39Å; G50-V54 PolarHBondContact O-N 2.8Å; V51-V54 PolarHBondContact O-N 2.88Å; V54-G56 VanDerWaalsContact C-N 3.3Å; V54-G56 PolarHBondContact O-N 3.03Å; V54-N57 PolarHBondContact O-N 3.45Å; V54-M58 HydrophobicContact CG1-CG 4.26Å; V54-M58 HydrophobicContact CG1-SD 3.65Å; V54-M58 WeakPolarHBondContact O-CB 3.44Å; V54-M58 WeakPolarHBondContact O-CG 3.27Å; V54-M58 PolarHBondContact O-N 3.5Å; V54-W250 HydrophobicContact CG1-CB 4.33Å; V54-L253 HydrophobicContact CG2-CB 3.82Å; V54-L253 HydrophobicContact CG2-CD2 3.88Å; V54-L253 HydrophobicContact CG2-CG 4.32Å; V54-S274 WeakPolarHBondContact CG1-OG 3.02Å
55	V	84.9	Confident	84	Confident	20 Å²	20	27.2 Å²	27.2	12%	0.121	16%	0.159	C	C	.	.	H	α-helix	trans	-60.2	-43.9	177.7	174.4	0	0	0	0	110.3	V51 I59 V278	V51-V55 HydrophobicContact CG1-CG2 4.15Å; V51-V55 WeakPolarHBondContact O-CB 3.38Å; V51-V55 VanDerWaalsContact O-CG2 3.28Å; V51-V55 WeakPolarHBondContact O-CG2 3.31Å; V51-V55 PolarHBondContact O-N 3.45Å; V55-I59 HydrophobicContact CG1-CD1 3.53Å; V55-I59 HydrophobicContact CG1-CG1 4.17Å; V55-I59 WeakPolarHBondContact O-CB 3.21Å; V55-I59 VanDerWaalsContact O-CG1 3.27Å; V55-I59 WeakPolarHBondContact O-CG1 3.47Å; V55-I59 PolarHBondContact O-N 2.8Å; V55-V278 HydrophobicContact CG1-CG2 4.44Å; V55-V278 HydrophobicContact CG2-CG2 4.22Å
56	G	79	Confident	84.7	Confident	6 Å²	6	26.2 Å²	26.2	6%	0.062	15%	0.154	C	C	.	.	H	α-helix	trans	-64.2	-37.8	177.8	0	0	0	0	0	113	S52 L53 V54 K199	S52-G56 WeakPolarHBondContact O-CA 3.27Å; S52-G56 PolarHBondContact O-N 2.69Å; L53-G56 PolarHBondContact O-N 2.75Å; V54-G56 VanDerWaalsContact C-N 3.3Å; V54-G56 PolarHBondContact O-N 3.03Å; G56-K199 WeakPolarHBondContact O-CE 3.22Å; G56-K199 PolarHBondContact O-NZ 3.02Å
57	N	78.8	Confident	85.1	Confident	48 Å²	48	24.4 Å²	24.4	26%	0.257	14%	0.141	S	C	.	.	H	α-helix	trans	-79.2	-39.8	-179.8	-73.8	-5.7	0	0	0	112.3	L53 V54 T252	L53-N57 WeakPolarHBondContact O-CB 3.28Å; L53-N57 VanDerWaalsContact O-CG 3.28Å; L53-N57 PolarHBondContact O-N 3.49Å; V54-N57 PolarHBondContact O-N 3.45Å; N57-T252 WeakPolarHBondContact ND2-CB 3.43Å; N57-T252 WeakPolarHBondContact ND2-CG2 3.46Å; N57-T252 PolarHBondContact ND2-OG1 3.37Å
58	M	85	Confident	85.4	Confident	5 Å²	5	23.5 Å²	23.5	3%	0.025	14%	0.135	C	C	.	.	H	α-helix	trans	-67.5	-50.2	177.9	-68.4	176.8	77.7	0	0	111.4	V54 G60 Y247 W250 M275 V278 Y282	V54-M58 HydrophobicContact CG1-CG 4.26Å; V54-M58 HydrophobicContact CG1-SD 3.65Å; V54-M58 WeakPolarHBondContact O-CB 3.44Å; V54-M58 WeakPolarHBondContact O-CG 3.27Å; V54-M58 PolarHBondContact O-N 3.5Å; M58-G60 VanDerWaalsContact C-N 3.27Å; M58-G60 PolarHBondContact O-N 3.34Å; M58-Y247 HydrophobicContact CE-CD1 3.88Å; M58-Y247 VanDerWaalsContact CE-O 3.28Å; M58-Y247 WeakPolarHBondContact CE-O 3.17Å; M58-W250 HydrophobicContact CE-CB 4.36Å; M58-W250 HydrophobicContact CG-CB 4.37Å; M58-W250 HydrophobicContact SD-CB 3.83Å; M58-M275 HydrophobicContact CE-CE 3.6Å; M58-M275 HydrophobicContact CE-SD 3.53Å; M58-M275 VanDerWaalsContact CE-SD 3.53Å; M58-M275 HydrophobicContact SD-CE 4.42Å; M58-M275 HydrophobicContact SD-SD 3.54Å; M58-V278 HydrophobicContact CB-CG1 4.22Å; M58-V278 HydrophobicContact CB-CG2 4.26Å; M58-V278 HydrophobicContact CE-CB 4.19Å; M58-V278 HydrophobicContact CE-CG1 3.81Å; M58-V278 HydrophobicContact CE-CG2 4.44Å; M58-V278 HydrophobicContact SD-CB 4.41Å; M58-V278 HydrophobicContact SD-CG1 4.4Å; M58-V278 HydrophobicContact SD-CG2 4.02Å; M58-Y282 VanDerWaalsContact C-OH 3.28Å; M58-Y282 PolarHBondContact O-OH 3.01Å
59	I	84	Confident	85.9	Confident	1 Å²	1	17 Å²	17	1%	0.005	10%	0.101	C	C	.	.	S	Bend	trans	-71.8	86.2	178.2	-59.3	-175.8	0	0	0	108.3	V55 K199 L203 V278 I281 Y282	V55-I59 HydrophobicContact CG1-CD1 3.53Å; V55-I59 HydrophobicContact CG1-CG1 4.17Å; V55-I59 WeakPolarHBondContact O-CB 3.21Å; V55-I59 VanDerWaalsContact O-CG1 3.27Å; V55-I59 WeakPolarHBondContact O-CG1 3.47Å; V55-I59 PolarHBondContact O-N 2.8Å; I59-K199 HydrophobicContact CG2-CD 4.47Å; I59-K199 VanDerWaalsContact O-CD 3.26Å; I59-K199 WeakPolarHBondContact O-CD 3.47Å; I59-K199 WeakPolarHBondContact O-CE 3.22Å; I59-K199 PolarHBondContact O-NZ 3Å; I59-L203 HydrophobicContact CG2-CD1 3.19Å; I59-V278 HydrophobicContact CD1-CG2 4.29Å; I59-V278 HydrophobicContact CG1-CG1 4.32Å; I59-V278 HydrophobicContact CG1-CG2 4.06Å; I59-I281 HydrophobicContact CD1-CD1 3.73Å; I59-I281 HydrophobicContact CD1-CG2 4.33Å; I59-Y282 WeakPolarHBondContact CA-OH 3.45Å; I59-Y282 HydrophobicContact CG1-CE1 4.16Å
60	G	77.8	Confident	86.6	Confident	9 Å²	9	12.9 Å²	12.9	9%	0.093	8%	0.079	C	C	.	.	S	Bend	trans	-126	-144.6	-176.7	0	0	0	0	0	112.7	M58 G62 F64	M58-G60 VanDerWaalsContact C-N 3.27Å; M58-G60 PolarHBondContact O-N 3.34Å; G60-G62 PolarHBondContact O-N 2.88Å; G60-F64 WeakPolarHBondContact O-CD2 3.28Å
61	S	77.8	Confident	87.1	Confident	7 Å²	7	12.7 Å²	12.7	5%	0.049	8%	0.077	C	C	.	.	S	Bend	trans	-67.7	-23.4	173.9	57.1	0	0	0	0	112.9	I63 F64 V65 I143	S61-I63 PolarHBondContact O-N 3.41Å; S61-F64 WeakPolarHBondContact O-CB 3.45Å; S61-F64 PolarHBondContact O-N 3.02Å; S61-V65 PolarHBondContact O-N 3.47Å; S61-I143 VanDerWaalsContact OG-CG1 3.26Å; S61-I143 WeakPolarHBondContact OG-CG1 3.07Å
62	G	87.8	Confident	87.5	Confident	5 Å²	5	15.2 Å²	15.2	5%	0.052	9%	0.092	C	C	.	.	H	α-helix	trans	-53.7	-50.9	-174.4	0	0	0	0	0	113.4	G60 F64 V65 S66 S246	G60-G62 PolarHBondContact O-N 2.88Å; G62-F64 PolarHBondContact O-N 3.33Å; G62-V65 PolarHBondContact O-N 2.87Å; G62-S66 VanDerWaalsContact O-CB 3.27Å; G62-S66 WeakPolarHBondContact O-CB 3.49Å; G62-S66 PolarHBondContact O-N 2.88Å; G62-S66 PolarHBondContact O-OG 2.95Å; G62-S66 VanDerWaalsContact O-OG 3.12Å; G62-S246 WeakPolarHBondContact CA-OG 3.27Å; G62-S246 PolarHBondContact O-OG 2.7Å; G62-S246 VanDerWaalsContact O-OG 3.05Å
63	I	91.8	Very high	88	Confident	0 Å²	0	14.5 Å²	14.5	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-62.9	-15.8	-177.6	-167.8	54.7	0	0	0	113.5	S61 P67 W84 L203 S246 Y282 T285	S61-I63 PolarHBondContact O-N 3.41Å; I63-P67 WeakPolarHBondContact O-CD 3.33Å; I63-P67 WeakPolarHBondContact O-CG 3.41Å; I63-W84 HydrophobicContact CD1-CH2 3.5Å; I63-W84 HydrophobicContact CD1-CZ2 4.01Å; I63-W84 HydrophobicContact CD1-CZ3 3.98Å; I63-L203 HydrophobicContact CG2-CD1 4.36Å; I63-L203 HydrophobicContact CG2-CD2 4.09Å; I63-S246 PolarHBondContact N-OG 2.99Å; I63-Y282 HydrophobicContact CB-CD1 4.07Å; I63-Y282 HydrophobicContact CB-CE1 3.73Å; I63-Y282 HydrophobicContact CD1-CD1 3.59Å; I63-Y282 HydrophobicContact CD1-CE1 4.14Å; I63-Y282 HydrophobicContact CD1-CG 3.82Å; I63-Y282 HydrophobicContact CG1-CD1 3.7Å; I63-Y282 HydrophobicContact CG1-CE1 3.9Å; I63-Y282 HydrophobicContact CG1-CG 4.43Å; I63-Y282 HydrophobicContact CG2-CE1 4.31Å; I63-T285 HydrophobicContact CD1-CG2 4.42Å; I63-T285 HydrophobicContact CG1-CG2 4.04Å
64	F	90.1	Very high	88.7	Confident	2 Å²	2	12.4 Å²	12.4	1%	0.009	7%	0.073	C	C	.	.	H	α-helix	trans	-93.2	-14.7	178.8	-62.5	-59.5	0	0	0	113.1	G60 S61 G62 T146 Y150 L203 I206 A305 V324	G60-F64 WeakPolarHBondContact O-CD2 3.28Å; S61-F64 WeakPolarHBondContact O-CB 3.45Å; S61-F64 PolarHBondContact O-N 3.02Å; G62-F64 PolarHBondContact O-N 3.33Å; F64-T146 HydrophobicContact CB-CG2 4.39Å; F64-Y150 HydrophobicContact CB-CE2 3.88Å; F64-Y150 WeakPolarHBondContact CB-OH 3.48Å; F64-Y150 PolarHBondContact O-OH 3.01Å; F64-Y150 VanDerWaalsContact O-OH 3.13Å; F64-L203 HydrophobicContact CE1-CD2 3.88Å; F64-L203 HydrophobicContact CZ-CD2 3.71Å; F64-L203 HydrophobicContact CZ-CG 4.09Å; F64-I206 HydrophobicContact CE1-CD1 4.33Å; F64-A305 HydrophobicContact CD1-CB 3.81Å; F64-A305 HydrophobicContact CE1-CB 4.09Å; F64-V324 HydrophobicContact CB-CG1 4.13Å; F64-V324 HydrophobicContact CD1-CG1 4.12Å; F64-V324 HydrophobicContact CD1-CG2 3.78Å; F64-V324 HydrophobicContact CD2-CB 4.48Å; F64-V324 HydrophobicContact CD2-CG1 3.55Å; F64-V324 HydrophobicContact CD2-CG2 4.24Å; F64-V324 HydrophobicContact CE1-CG1 4.48Å; F64-V324 HydrophobicContact CE1-CG2 3.49Å; F64-V324 VanDerWaalsContact CE1-CG2 3.49Å; F64-V324 HydrophobicContact CE2-CB 4.45Å; F64-V324 HydrophobicContact CE2-CG1 3.96Å; F64-V324 HydrophobicContact CE2-CG2 3.98Å; F64-V324 HydrophobicContact CG-CG1 3.65Å; F64-V324 HydrophobicContact CG-CG2 4.15Å; F64-V324 HydrophobicContact CZ-CG1 4.41Å; F64-V324 HydrophobicContact CZ-CG2 3.6Å
65	V	91.3	Very high	89.2	Confident	17 Å²	17	14.4 Å²	14.4	10%	0.103	9%	0.089	C	C	.	.	H	α-helix	trans	-112.2	-46	179.3	179.6	0	0	0	0	111.9	S61 G62 K68 T146 V386 F387 I390	S61-V65 PolarHBondContact O-N 3.47Å; G62-V65 PolarHBondContact O-N 2.87Å; V65-K68 PolarHBondContact O-N 3.31Å; V65-T146 HydrophobicContact CG2-CG2 3.58Å; V65-T146 WeakPolarHBondContact CG2-OG1 3.45Å; V65-V386 HydrophobicContact CG1-CG1 4.17Å; V65-F387 HydrophobicContact CG1-CE1 4.12Å; V65-F387 HydrophobicContact CG1-CZ 4.22Å; V65-I390 HydrophobicContact CG1-CD1 4.01Å
66	S	94.4	Very high	89.6	Confident	0 Å²	0	13.5 Å²	13.5	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-58.2	-33.5	-173.6	-65.7	0	0	0	0	115.6	G62 K68 G69 V70 S242 S246	G62-S66 VanDerWaalsContact O-CB 3.27Å; G62-S66 WeakPolarHBondContact O-CB 3.49Å; G62-S66 PolarHBondContact O-N 2.88Å; G62-S66 PolarHBondContact O-OG 2.95Å; G62-S66 VanDerWaalsContact O-OG 3.12Å; S66-K68 VanDerWaalsContact C-N 3.28Å; S66-K68 PolarHBondContact O-N 2.95Å; S66-G69 PolarHBondContact O-N 2.59Å; S66-G69 VanDerWaalsContact O-N 3.12Å; S66-V70 VanDerWaalsContact O-CG2 3.31Å; S66-V70 WeakPolarHBondContact O-CG2 3.23Å; S66-V70 PolarHBondContact O-N 3.42Å; S66-S242 WeakPolarHBondContact CB-O 3.45Å; S66-S242 PolarHBondContact OG-O 3Å; S66-S246 WeakPolarHBondContact CB-OG 3.46Å; S66-S246 PolarHBondContact OG-OG 3.28Å
67	P	95.2	Very high	90.4	Very high	0 Å²	0	14 Å²	14	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-54.3	-42.8	178.4	-28.6	36.1	0	0	0	113.2	I63 L71 W84 Y289	I63-P67 WeakPolarHBondContact O-CD 3.33Å; I63-P67 WeakPolarHBondContact O-CG 3.41Å; P67-L71 VanDerWaalsContact O-CB 3.28Å; P67-L71 WeakPolarHBondContact O-CB 3.46Å; P67-L71 PolarHBondContact O-N 3.24Å; P67-W84 HydrophobicContact CG-CZ2 4.19Å; P67-Y289 HydrophobicContact CB-CD2 4.28Å; P67-Y289 HydrophobicContact CG-CD2 4.16Å; P67-Y289 HydrophobicContact CG-CE2 3.95Å
68	K	94.6	Very high	91.1	Very high	30 Å²	30	12 Å²	12	13%	0.13	7%	0.074	C	C	.	.	H	α-helix	trans	-60.9	-51	174.8	172.8	169.5	177	167.7	0	111.2	V65 S66 V70 L71 V72 V298 L299 S301 D302 V304 F387	V65-K68 PolarHBondContact O-N 3.31Å; S66-K68 VanDerWaalsContact C-N 3.28Å; S66-K68 PolarHBondContact O-N 2.95Å; K68-V70 PolarHBondContact O-N 3.47Å; K68-L71 PolarHBondContact O-N 2.84Å; K68-V72 HydrophobicContact CG-CG2 4.37Å; K68-V72 VanDerWaalsContact O-CG2 3.28Å; K68-V72 WeakPolarHBondContact O-CG2 3.47Å; K68-V72 PolarHBondContact O-N 3.21Å; K68-V298 HydrophobicContact CB-CG1 4.49Å; K68-L299 WeakPolarHBondContact CE-O 3.4Å; K68-L299 PolarHBondContact NZ-O 3.08Å; K68-L299 VanDerWaalsContact NZ-O 3.16Å; K68-S301 WeakPolarHBondContact CD-O 3.48Å; K68-S301 PolarHBondContact NZ-O 3.24Å; K68-S301 VanDerWaalsContact NZ-O 3.11Å; K68-D302 IonicContact NZ-OD1 2.69Å; K68-D302 PolarHBondContact NZ-OD1 3.34Å; K68-V304 HydrophobicContact CB-CG2 4.33Å; K68-F387 HydrophobicContact CB-CZ 4.08Å; K68-F387 HydrophobicContact CD-CE2 4.28Å; K68-F387 HydrophobicContact CD-CZ 4.22Å; K68-F387 HydrophobicContact CG-CE2 4.22Å; K68-F387 HydrophobicContact CG-CZ 3.87Å
69	G	93.3	Very high	91.6	Very high	1 Å²	1	12.1 Å²	12.1	1%	0.01	8%	0.075	C	C	.	.	H	α-helix	trans	-60.8	-42.1	-179.9	0	0	0	0	0	113.7	S66 H73	S66-G69 PolarHBondContact O-N 2.59Å; S66-G69 VanDerWaalsContact O-N 3.12Å; G69-H73 PolarHBondContact O-CD2 3.13Å
70	V	96.2	Very high	92.2	Very high	0 Å²	0	12.1 Å²	12.1	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-63.5	-45.3	175.4	179.3	0	0	0	0	110.1	S66 K68 H73 T74 S80 V83 W84 A239 A243	S66-V70 VanDerWaalsContact O-CG2 3.31Å; S66-V70 WeakPolarHBondContact O-CG2 3.23Å; S66-V70 PolarHBondContact O-N 3.42Å; K68-V70 PolarHBondContact O-N 3.47Å; V70-H73 PolarHBondContact O-N 2.85Å; V70-T74 HydrophobicContact CG1-CG2 4.12Å; V70-T74 WeakPolarHBondContact O-CB 3.42Å; V70-T74 WeakPolarHBondContact O-CG2 3.35Å; V70-T74 PolarHBondContact O-N 3.14Å; V70-T74 PolarHBondContact O-OG1 2.82Å; V70-S80 WeakPolarHBondContact CG1-OG 3.21Å; V70-V83 HydrophobicContact CG1-CB 4.03Å; V70-V83 HydrophobicContact CG1-CG1 3.97Å; V70-W84 HydrophobicContact CG2-CZ2 4.37Å; V70-A239 HydrophobicContact CG1-CB 4.39Å; V70-A243 HydrophobicContact CG2-CB 3.98Å
71	L	94.9	Very high	93.1	Very high	0 Å²	0	13.3 Å²	13.3	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-71.1	-35.6	-175.6	-158.7	67.2	0	0	0	112.8	P67 K68 H73 T74 A75 Y77 Y290 I295 V298 L299	P67-L71 VanDerWaalsContact O-CB 3.28Å; P67-L71 WeakPolarHBondContact O-CB 3.46Å; P67-L71 PolarHBondContact O-N 3.24Å; K68-L71 PolarHBondContact O-N 2.84Å; L71-H73 PolarHBondContact O-N 3.46Å; L71-T74 WeakPolarHBondContact CA-OG1 3.45Å; L71-T74 PolarHBondContact O-N 3.34Å; L71-A75 WeakPolarHBondContact O-CA 3.48Å; L71-A75 PolarHBondContact O-N 3.4Å; L71-Y77 HydrophobicContact CD1-CD1 4.03Å; L71-Y77 HydrophobicContact CD2-CD1 4.48Å; L71-Y77 HydrophobicContact CD2-CE1 4.28Å; L71-Y290 HydrophobicContact CD1-CE1 4.4Å; L71-Y290 HydrophobicContact CD2-CE1 4.2Å; L71-I295 HydrophobicContact CD2-CB 4.32Å; L71-I295 HydrophobicContact CD2-CG1 4.27Å; L71-I295 HydrophobicContact CD2-CG2 4.03Å; L71-I295 HydrophobicContact CG-CG2 4.31Å; L71-V298 HydrophobicContact CD2-CB 3.81Å; L71-V298 HydrophobicContact CD2-CG1 3.75Å; L71-V298 HydrophobicContact CD2-CG2 4.25Å; L71-L299 HydrophobicContact CB-CD2 4.33Å
72	V	94.1	Very high	94	Very high	73 Å²	73	16.1 Å²	16.1	44%	0.442	9%	0.093	S	C	.	.	H	α-helix	trans	-52.1	-45.2	172.6	165.8	0	0	0	0	110.8	K68 L299	K68-V72 HydrophobicContact CG-CG2 4.37Å; K68-V72 VanDerWaalsContact O-CG2 3.28Å; K68-V72 WeakPolarHBondContact O-CG2 3.47Å; K68-V72 PolarHBondContact O-N 3.21Å; V72-L299 HydrophobicContact CB-CD2 4.22Å; V72-L299 HydrophobicContact CG2-CD2 3.4Å; V72-L299 VanDerWaalsContact CG2-CD2 3.4Å
73	H	93.8	Very high	94.4	Very high	35 Å²	35	16 Å²	16	16%	0.162	9%	0.091	C	C	.	.	H	α-helix	trans	-90.3	-27	-173.6	-70.1	-60.3	0	0	0	114	G69 V70 L71 S230 N235 A239	G69-H73 PolarHBondContact O-CD2 3.13Å; V70-H73 PolarHBondContact O-N 2.85Å; L71-H73 PolarHBondContact O-N 3.46Å; H73-S230 WeakPolarHBondContact O-CB 3.36Å; H73-S230 PolarHBondContact O-OG 3.2Å; H73-N235 HydrophobicContact CB-CB 4.24Å; H73-N235 VanDerWaalsContact CB-O 3.32Å; H73-N235 WeakPolarHBondContact CB-O 3.46Å; H73-N235 PolarHBondContact ND1-OD1 3.18Å; H73-N235 WeakPolarHBondContact O-CB 3.32Å; H73-A239 HydrophobicContact CB-CB 3.8Å
74	T	94.8	Very high	94.7	Very high	1 Å²	1	16 Å²	16	1%	0.006	9%	0.091	C	C	.	.	H	α-helix	trans	-87.9	-25.9	179.4	52.1	0	0	0	0	113.2	V70 L71 S76 M79 V83 S230 A239	V70-T74 HydrophobicContact CG1-CG2 4.12Å; V70-T74 WeakPolarHBondContact O-CB 3.42Å; V70-T74 WeakPolarHBondContact O-CG2 3.35Å; V70-T74 PolarHBondContact O-N 3.14Å; V70-T74 PolarHBondContact O-OG1 2.82Å; L71-T74 WeakPolarHBondContact CA-OG1 3.45Å; L71-T74 PolarHBondContact O-N 3.34Å; T74-S76 PolarHBondContact O-N 3.02Å; T74-M79 HydrophobicContact CG2-CB 4.41Å; T74-M79 HydrophobicContact CG2-CG 4.01Å; T74-V83 HydrophobicContact CG2-CB 4.46Å; T74-V83 HydrophobicContact CG2-CG2 3.67Å; T74-S230 PolarHBondContact O-N 2.93Å; T74-A239 HydrophobicContact CG2-CB 3.77Å
75	A	93.4	Very high	95	Very high	42 Å²	42	17.9 Å²	17.9	35%	0.347	11%	0.107	S	C	.	.			trans	58.1	5.7	180	0	0	0	0	0	115.9	L71 G228	L71-A75 WeakPolarHBondContact O-CA 3.48Å; L71-A75 PolarHBondContact O-N 3.4Å; A75-G228 WeakPolarHBondContact CB-O 3.24Å
76	S	94.6	Very high	95.2	Very high	1 Å²	1	21 Å²	21	1%	0.007	12%	0.122	C	C	.	.	S	Bend	trans	-148	150	178.1	78.7	0	0	0	0	111.7	T74 M79 S80 A225 E227 S229	T74-S76 PolarHBondContact O-N 3.02Å; S76-M79 WeakPolarHBondContact OG-CB 3.49Å; S76-M79 PolarHBondContact OG-N 3.19Å; S76-S80 VanDerWaalsContact O-CB 3.3Å; S76-S80 WeakPolarHBondContact O-CB 3.22Å; S76-S80 PolarHBondContact O-N 3.03Å; S76-A225 WeakPolarHBondContact CB-O 3.42Å; S76-E227 VanDerWaalsContact CB-O 3.31Å; S76-E227 WeakPolarHBondContact CB-O 3.44Å; S76-S229 WeakPolarHBondContact CB-OG 3.4Å; S76-S229 PolarHBondContact OG-OG 3.02Å
77	Y	94.6	Very high	95.2	Very high	18 Å²	18	21 Å²	21	7%	0.071	12%	0.122	C	C	.	.	H	α-helix	trans	-66.1	-42.9	-179.8	-55.8	-54.7	0	0	0	112.2	L71 S80 L81 H221 A225 Y290 L293 N294 I295	L71-Y77 HydrophobicContact CD1-CD1 4.03Å; L71-Y77 HydrophobicContact CD2-CD1 4.48Å; L71-Y77 HydrophobicContact CD2-CE1 4.28Å; Y77-S80 WeakPolarHBondContact O-CB 3.28Å; Y77-S80 PolarHBondContact O-N 3.4Å; Y77-L81 WeakPolarHBondContact O-CG 3.29Å; Y77-L81 PolarHBondContact O-N 3.14Å; Y77-H221 HydrophobicContact CD2-CB 4.02Å; Y77-H221 WeakPolarHBondContact CD2-O 3.35Å; Y77-H221 HydrophobicContact CE2-CB 3.59Å; Y77-H221 AromaticContact CE2-CG 3.91Å; Y77-A225 PolarHBondContact N-O 3.12Å; Y77-Y290 AromaticContact CD1-CD1 3.55Å; Y77-Y290 HydrophobicContact CD1-CD1 3.55Å; Y77-Y290 AromaticContact CD1-CD2 3.83Å; Y77-Y290 HydrophobicContact CD1-CD2 3.83Å; Y77-Y290 AromaticContact CD1-CE1 4Å; Y77-Y290 HydrophobicContact CD1-CE1 4Å; Y77-Y290 HydrophobicContact CD1-CE2 4.22Å; Y77-Y290 AromaticContact CD1-CG 3.48Å; Y77-Y290 HydrophobicContact CD1-CG 3.48Å; Y77-Y290 VanDerWaalsContact CD1-CG 3.48Å; Y77-Y290 AromaticContact CE1-CD1 3.82Å; Y77-Y290 HydrophobicContact CE1-CD1 3.82Å; Y77-Y290 HydrophobicContact CE1-CE1 4.4Å; Y77-Y290 HydrophobicContact CE1-CG 4.06Å; Y77-Y290 HydrophobicContact CG-CD2 4.16Å; Y77-Y290 HydrophobicContact CG-CG 4.06Å; Y77-L293 PolarHBondContact OH-O 3.35Å; Y77-N294 VanDerWaalsContact OH-C 3.25Å; Y77-N294 VanDerWaalsContact OH-CA 3.22Å; Y77-N294 WeakPolarHBondContact OH-CA 3.28Å; Y77-I295 HydrophobicContact CD1-CG1 4.13Å; Y77-I295 HydrophobicContact CE1-CB 4.45Å; Y77-I295 HydrophobicContact CE1-CD1 4.28Å; Y77-I295 HydrophobicContact CE1-CG1 3.37Å; Y77-I295 HydrophobicContact CE2-CD1 4.45Å; Y77-I295 HydrophobicContact CE2-CG1 4.05Å; Y77-I295 WeakPolarHBondContact OH-CG1 3.17Å; Y77-I295 PolarHBondContact OH-N 3.34Å
78	G	94.6	Very high	95.2	Very high	5 Å²	5	21 Å²	21	5%	0.052	12%	0.122	C	C	.	.	H	α-helix	trans	-63.4	-46.3	-179.1	0	0	0	0	0	111.7	L81 I82 A225	G78-L81 PolarHBondContact O-N 3.11Å; G78-I82 WeakPolarHBondContact O-CG1 3.45Å; G78-I82 PolarHBondContact O-N 2.86Å; G78-I82 VanDerWaalsContact O-N 3.11Å; G78-A225 WeakPolarHBondContact CA-O 3.11Å; G78-A225 PolarHBondContact N-O 3.43Å
79	M	95.7	Very high	95.2	Very high	8 Å²	8	25.1 Å²	25.1	4%	0.039	15%	0.145	C	C	.	.	H	α-helix	trans	-68.2	-37.2	177.5	-167.5	64.8	-172.1	0	0	111.5	T74 S76 L81 I82 V83 W231 L236	T74-M79 HydrophobicContact CG2-CB 4.41Å; T74-M79 HydrophobicContact CG2-CG 4.01Å; S76-M79 WeakPolarHBondContact OG-CB 3.49Å; S76-M79 PolarHBondContact OG-N 3.19Å; M79-L81 PolarHBondContact O-N 3.27Å; M79-I82 PolarHBondContact O-N 2.77Å; M79-I82 HydrophobicContact SD-CD1 4.44Å; M79-V83 WeakPolarHBondContact O-CG2 3.48Å; M79-V83 PolarHBondContact O-N 2.95Å; M79-W231 HydrophobicContact SD-CZ3 4.5Å; M79-L236 HydrophobicContact CE-CD1 3.46Å; M79-L236 VanDerWaalsContact CE-CD1 3.46Å; M79-L236 HydrophobicContact CE-CD2 3.84Å; M79-L236 HydrophobicContact CE-CG 4.29Å
80	S	96.5	Very high	95.2	Very high	0 Å²	0	25.9 Å²	25.9	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-56.7	-47.9	172.2	-179.6	0	0	0	0	112.4	V70 S76 Y77 I82 V83 W84 Y290	V70-S80 WeakPolarHBondContact CG1-OG 3.21Å; S76-S80 VanDerWaalsContact O-CB 3.3Å; S76-S80 WeakPolarHBondContact O-CB 3.22Å; S76-S80 PolarHBondContact O-N 3.03Å; Y77-S80 WeakPolarHBondContact O-CB 3.28Å; Y77-S80 PolarHBondContact O-N 3.4Å; S80-I82 VanDerWaalsContact C-N 3.32Å; S80-I82 PolarHBondContact O-N 3.37Å; S80-V83 WeakPolarHBondContact O-CB 3.42Å; S80-V83 PolarHBondContact O-N 3.07Å; S80-V83 VanDerWaalsContact O-N 3.13Å; S80-W84 VanDerWaalsContact O-CD1 3.22Å; S80-W84 PolarHBondContact O-N 2.82Å; S80-Y290 PolarHBondContact OG-OH 3.19Å
81	L	96.5	Very high	95.1	Very high	34 Å²	34	25.9 Å²	25.9	18%	0.178	15%	0.148	C	C	.	.	H	α-helix	trans	-63.2	-36.9	177.9	-68.8	174.5	0	0	0	112.5	Y77 G78 M79 W84 A85 F222 N286 V287 Y290	Y77-L81 WeakPolarHBondContact O-CG 3.29Å; Y77-L81 PolarHBondContact O-N 3.14Å; G78-L81 PolarHBondContact O-N 3.11Å; M79-L81 PolarHBondContact O-N 3.27Å; L81-W84 PolarHBondContact O-N 3.29Å; L81-A85 PolarHBondContact O-N 3.15Å; L81-F222 HydrophobicContact CD1-CE1 4.32Å; L81-N286 HydrophobicContact CD2-CB 3.8Å; L81-V287 HydrophobicContact CD1-CG2 4.05Å; L81-V287 HydrophobicContact CD2-CG2 3.92Å; L81-Y290 HydrophobicContact CD2-CD2 4.31Å; L81-Y290 HydrophobicContact CD2-CE2 4.11Å; L81-Y290 HydrophobicContact CG-CD2 4.29Å; L81-Y290 HydrophobicContact CG-CE2 4.14Å
82	I	96.4	Very high	95	Very high	67 Å²	67	27.8 Å²	27.8	34%	0.344	16%	0.16	S	C	.	.	H	α-helix	trans	-61.4	-44.8	172.7	-69.6	178.6	0	0	0	110.6	G78 M79 S80 W84 A85 I86 F226	G78-I82 WeakPolarHBondContact O-CG1 3.45Å; G78-I82 PolarHBondContact O-N 2.86Å; G78-I82 VanDerWaalsContact O-N 3.11Å; M79-I82 PolarHBondContact O-N 2.77Å; M79-I82 HydrophobicContact SD-CD1 4.44Å; S80-I82 VanDerWaalsContact C-N 3.32Å; S80-I82 PolarHBondContact O-N 3.37Å; I82-W84 VanDerWaalsContact C-N 3.33Å; I82-W84 PolarHBondContact O-N 2.84Å; I82-A85 PolarHBondContact O-N 2.89Å; I82-I86 HydrophobicContact CG2-CD1 3.58Å; I82-I86 HydrophobicContact CG2-CG1 4.17Å; I82-I86 WeakPolarHBondContact O-CB 3.42Å; I82-I86 WeakPolarHBondContact O-CG1 3.46Å; I82-I86 PolarHBondContact O-N 3.2Å; I82-F226 HydrophobicContact CD1-CE1 3.56Å; I82-F226 HydrophobicContact CD1-CZ 3.99Å; I82-F226 HydrophobicContact CG1-CE1 4.36Å
83	V	96.6	Very high	95	Very high	2 Å²	2	25.1 Å²	25.1	1%	0.012	14%	0.144	C	C	.	.	H	α-helix	trans	-60.4	-43.1	177.3	172.1	0	0	0	0	111.5	V70 T74 M79 S80 A85 I86 G87 L236 A239 L240 A243	V70-V83 HydrophobicContact CG1-CB 4.03Å; V70-V83 HydrophobicContact CG1-CG1 3.97Å; T74-V83 HydrophobicContact CG2-CB 4.46Å; T74-V83 HydrophobicContact CG2-CG2 3.67Å; M79-V83 WeakPolarHBondContact O-CG2 3.48Å; M79-V83 PolarHBondContact O-N 2.95Å; S80-V83 WeakPolarHBondContact O-CB 3.42Å; S80-V83 PolarHBondContact O-N 3.07Å; S80-V83 VanDerWaalsContact O-N 3.13Å; V83-A85 VanDerWaalsContact C-N 3.34Å; V83-A85 PolarHBondContact O-N 3.42Å; V83-I86 PolarHBondContact O-N 3.49Å; V83-G87 PolarHBondContact O-N 2.99Å; V83-L236 HydrophobicContact CG2-CD1 3.3Å; V83-A239 HydrophobicContact CG1-CB 4.08Å; V83-A239 HydrophobicContact CG2-CB 4.27Å; V83-L240 HydrophobicContact CG1-CB 4.42Å; V83-L240 HydrophobicContact CG1-CD1 4.25Å; V83-A243 HydrophobicContact CG1-CB 3.96Å
84	W	97.1	Very high	94.9	Very high	0 Å²	0	23.5 Å²	23.5	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-61.6	-39.8	175.1	-81.9	104.9	0	0	0	113	I63 P67 V70 S80 L81 I82 G88 A243 S246 Y247 Y282 I283 N286	I63-W84 HydrophobicContact CD1-CH2 3.5Å; I63-W84 HydrophobicContact CD1-CZ2 4.01Å; I63-W84 HydrophobicContact CD1-CZ3 3.98Å; P67-W84 HydrophobicContact CG-CZ2 4.19Å; V70-W84 HydrophobicContact CG2-CZ2 4.37Å; S80-W84 VanDerWaalsContact O-CD1 3.22Å; S80-W84 PolarHBondContact O-N 2.82Å; L81-W84 PolarHBondContact O-N 3.29Å; I82-W84 VanDerWaalsContact C-N 3.33Å; I82-W84 PolarHBondContact O-N 2.84Å; W84-G88 PolarHBondContact O-N 2.72Å; W84-A243 HydrophobicContact CD2-CB 4.35Å; W84-A243 HydrophobicContact CE3-CB 4.33Å; W84-S246 WeakPolarHBondContact CH2-OG 3.15Å; W84-Y247 HydrophobicContact CE3-CD2 4.49Å; W84-Y247 AromaticContact CE3-CE2 3.67Å; W84-Y247 HydrophobicContact CE3-CE2 3.67Å; W84-Y247 HydrophobicContact CZ3-CE2 4.06Å; W84-Y247 WeakPolarHBondContact O-CE2 3.4Å; W84-Y247 PolarHBondContact O-OH 3.47Å; W84-Y282 HydrophobicContact CE3-CD2 4.02Å; W84-Y282 HydrophobicContact CE3-CG 4.31Å; W84-Y282 HydrophobicContact CH2-CD2 4.47Å; W84-Y282 AromaticContact CZ3-CD2 3.47Å; W84-Y282 HydrophobicContact CZ3-CD2 3.47Å; W84-Y282 VanDerWaalsContact CZ3-CD2 3.47Å; W84-Y282 HydrophobicContact CZ3-CE2 4.15Å; W84-Y282 AromaticContact CZ3-CG 3.87Å; W84-Y282 HydrophobicContact CZ3-CG 3.87Å; W84-I283 HydrophobicContact CB-CG1 4.42Å; W84-N286 WeakPolarHBondContact CZ2-ND2 3.25Å; W84-N286 VanDerWaalsContact NE1-CG 3.31Å; W84-N286 PolarHBondContact NE1-ND2 2.94Å; W84-N286 PolarHBondContact NE1-OD1 3.43Å; W84-N286 VanDerWaalsContact NE1-OD1 3.09Å
85	A	96.4	Very high	94.8	Very high	42 Å²	42	23.4 Å²	23.4	35%	0.347	14%	0.136	S	C	.	.	H	α-helix	trans	-68.5	-44.1	176.7	0	0	0	0	0	112.1	L81 I82 V83 G88 L89 I283	L81-A85 PolarHBondContact O-N 3.15Å; I82-A85 PolarHBondContact O-N 2.89Å; V83-A85 VanDerWaalsContact C-N 3.34Å; V83-A85 PolarHBondContact O-N 3.42Å; A85-G88 PolarHBondContact O-N 2.71Å; A85-L89 WeakPolarHBondContact O-CB 3.16Å; A85-L89 PolarHBondContact O-N 3.17Å; A85-I283 HydrophobicContact CB-CD1 4.12Å
86	I	95.3	Very high	94.8	Very high	82 Å²	82	23.5 Å²	23.5	42%	0.421	13%	0.13	S	C	.	.	H	α-helix	trans	-63.2	-44.1	176.3	-69.2	172.9	0	0	0	110.4	I82 V83 G88 L89 F90 L240	I82-I86 HydrophobicContact CG2-CD1 3.58Å; I82-I86 HydrophobicContact CG2-CG1 4.17Å; I82-I86 WeakPolarHBondContact O-CB 3.42Å; I82-I86 WeakPolarHBondContact O-CG1 3.46Å; I82-I86 PolarHBondContact O-N 3.2Å; V83-I86 PolarHBondContact O-N 3.49Å; I86-G88 VanDerWaalsContact C-N 3.34Å; I86-G88 PolarHBondContact O-N 3.21Å; I86-L89 PolarHBondContact O-N 2.95Å; I86-F90 VanDerWaalsContact O-CB 3.32Å; I86-F90 WeakPolarHBondContact O-CB 3.35Å; I86-F90 PolarHBondContact O-N 3.4Å; I86-L240 HydrophobicContact CG2-CD1 4.24Å
87	G	94.9	Very high	94.7	Very high	0 Å²	0	23.4 Å²	23.4	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-60.6	-41.5	176.5	0	0	0	0	0	112.7	V83 S91	V83-G87 PolarHBondContact O-N 2.99Å; G87-S91 WeakPolarHBondContact O-CB 3.39Å; G87-S91 PolarHBondContact O-N 2.93Å; G87-S91 PolarHBondContact O-OG 2.78Å
88	G	94.5	Very high	94.7	Very high	0 Å²	0	22.6 Å²	22.6	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-64.2	-47.4	174.5	0	0	0	0	0	112.3	W84 A85 I86 F90 S91 V92 Y247	W84-G88 PolarHBondContact O-N 2.72Å; A85-G88 PolarHBondContact O-N 2.71Å; I86-G88 VanDerWaalsContact C-N 3.34Å; I86-G88 PolarHBondContact O-N 3.21Å; G88-F90 PolarHBondContact O-N 3.04Å; G88-S91 PolarHBondContact O-N 3.28Å; G88-V92 WeakPolarHBondContact O-CG2 3.32Å; G88-V92 PolarHBondContact O-N 3.12Å; G88-Y247 VanDerWaalsContact CA-CZ 3.43Å; G88-Y247 VanDerWaalsContact N-CE2 3.32Å
89	L	94.6	Very high	94.5	Very high	117 Å²	117	22.3 Å²	22.3	61%	0.613	12%	0.124	S	C	*	.	H	α-helix	trans	-61.5	-45.8	177.7	-179.3	62.3	0	0	0	111.9	A85 I86 S91 V92 V93	A85-L89 WeakPolarHBondContact O-CB 3.16Å; A85-L89 PolarHBondContact O-N 3.17Å; I86-L89 PolarHBondContact O-N 2.95Å; L89-S91 VanDerWaalsContact C-N 3.29Å; L89-S91 PolarHBondContact O-N 3.3Å; L89-V92 PolarHBondContact O-N 3.39Å; L89-V93 WeakPolarHBondContact O-CG2 3.49Å; L89-V93 PolarHBondContact O-N 3.44Å; L89-V93 VanDerWaalsContact O-N 3.1Å
90	F	94.1	Very high	94.4	Very high	17 Å²	17	22 Å²	22	8%	0.075	12%	0.122	C	C	.	.	H	α-helix	trans	-58.5	-43.7	175.8	172.9	-98.8	0	0	0	111.3	I86 G88 V93 G94 L244 W398 F432 C435 L439	I86-F90 VanDerWaalsContact O-CB 3.32Å; I86-F90 WeakPolarHBondContact O-CB 3.35Å; I86-F90 PolarHBondContact O-N 3.4Å; G88-F90 PolarHBondContact O-N 3.04Å; F90-V93 PolarHBondContact O-N 3.32Å; F90-G94 PolarHBondContact O-N 2.78Å; F90-L244 HydrophobicContact CD1-CD1 3.99Å; F90-L244 HydrophobicContact CD1-CD2 3.52Å; F90-L244 HydrophobicContact CD1-CG 4.43Å; F90-L244 HydrophobicContact CE1-CD1 3.95Å; F90-L244 HydrophobicContact CE1-CD2 4.12Å; F90-L244 HydrophobicContact CG-CD2 4.48Å; F90-W398 HydrophobicContact CD1-CH2 4.45Å; F90-W398 HydrophobicContact CD1-CZ3 4.36Å; F90-W398 HydrophobicContact CE1-CD2 4.18Å; F90-W398 AromaticContact CE1-CE3 3.64Å; F90-W398 HydrophobicContact CE1-CE3 3.64Å; F90-W398 AromaticContact CE1-CH2 3.95Å; F90-W398 HydrophobicContact CE1-CH2 3.95Å; F90-W398 HydrophobicContact CE1-CZ2 4.47Å; F90-W398 AromaticContact CE1-CZ3 3.51Å; F90-W398 HydrophobicContact CE1-CZ3 3.51Å; F90-W398 HydrophobicContact CZ-CE3 4.11Å; F90-W398 HydrophobicContact CZ-CZ3 4.26Å; F90-F432 HydrophobicContact CD1-CE2 4.21Å; F90-F432 HydrophobicContact CD2-CD2 4.03Å; F90-F432 HydrophobicContact CD2-CE2 4.09Å; F90-F432 AromaticContact CE1-CE2 3.66Å; F90-F432 HydrophobicContact CE1-CE2 3.66Å; F90-F432 HydrophobicContact CE1-CZ 4.14Å; F90-F432 AromaticContact CE2-CD2 3.53Å; F90-F432 HydrophobicContact CE2-CD2 3.53Å; F90-F432 AromaticContact CE2-CE2 3.45Å; F90-F432 HydrophobicContact CE2-CE2 3.45Å; F90-F432 VanDerWaalsContact CE2-CE2 3.45Å; F90-F432 HydrophobicContact CE2-CG 4.31Å; F90-F432 HydrophobicContact CE2-CZ 4.18Å; F90-F432 HydrophobicContact CG-CE2 4.44Å; F90-F432 AromaticContact CZ-CD2 3.84Å; F90-F432 HydrophobicContact CZ-CD2 3.84Å; F90-F432 AromaticContact CZ-CE2 3.24Å; F90-F432 HydrophobicContact CZ-CE2 3.24Å; F90-F432 AromaticContact CZ-CZ 3.63Å; F90-F432 HydrophobicContact CZ-CZ 3.63Å; F90-C435 HydrophobicContact CD2-CB 3.58Å; F90-C435 HydrophobicContact CE2-CB 3.35Å; F90-C435 HydrophobicContact CZ-CB 4.5Å; F90-L439 HydrophobicContact CD1-CD1 4.48Å; F90-L439 HydrophobicContact CE1-CD1 3.68Å; F90-L439 HydrophobicContact CE2-CD1 4.21Å; F90-L439 HydrophobicContact CZ-CD1 3.51Å
91	S	93.5	Very high	94.2	Very high	0 Å²	0	22.2 Å²	22.2	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-66.8	-37.5	178.6	-56.5	0	0	0	0	112.3	G87 G88 L89 V93 G94 A95 Y247	G87-S91 WeakPolarHBondContact O-CB 3.39Å; G87-S91 PolarHBondContact O-N 2.93Å; G87-S91 PolarHBondContact O-OG 2.78Å; G88-S91 PolarHBondContact O-N 3.28Å; L89-S91 VanDerWaalsContact C-N 3.29Å; L89-S91 PolarHBondContact O-N 3.3Å; S91-V93 VanDerWaalsContact C-N 3.34Å; S91-V93 PolarHBondContact O-N 3.5Å; S91-G94 PolarHBondContact O-N 3.28Å; S91-A95 VanDerWaalsContact O-CB 3.26Å; S91-A95 WeakPolarHBondContact O-CB 3.31Å; S91-A95 PolarHBondContact O-N 3.36Å; S91-Y247 VanDerWaalsContact OG-CB 3.29Å; S91-Y247 WeakPolarHBondContact OG-CB 3.49Å
92	V	92.8	Very high	93.9	Very high	39 Å²	39	20.6 Å²	20.6	24%	0.236	12%	0.115	C	C	.	.	H	α-helix	trans	-59.1	-47	173.5	169.7	0	0	0	0	110.5	G88 L89 G94 A95 L96 M275	G88-V92 WeakPolarHBondContact O-CG2 3.32Å; G88-V92 PolarHBondContact O-N 3.12Å; L89-V92 PolarHBondContact O-N 3.39Å; V92-G94 PolarHBondContact O-N 3.18Å; V92-A95 PolarHBondContact O-N 3.34Å; V92-L96 HydrophobicContact CG1-CD1 4.06Å; V92-L96 VanDerWaalsContact O-CG 3.29Å; V92-L96 WeakPolarHBondContact O-CG 3.21Å; V92-L96 PolarHBondContact O-N 3.19Å; V92-M275 HydrophobicContact CG2-CB 3.64Å; V92-M275 HydrophobicContact CG2-CE 4.4Å; V92-M275 HydrophobicContact CG2-CG 4.48Å
93	V	93.6	Very high	93.6	Very high	18 Å²	18	17.7 Å²	17.7	11%	0.109	10%	0.1	C	C	.	.	H	α-helix	trans	-61.8	-45.9	178.9	178.1	0	0	0	0	110.5	L89 F90 S91 L96 C97 F428 F432	L89-V93 WeakPolarHBondContact O-CG2 3.49Å; L89-V93 PolarHBondContact O-N 3.44Å; L89-V93 VanDerWaalsContact O-N 3.1Å; F90-V93 PolarHBondContact O-N 3.32Å; S91-V93 VanDerWaalsContact C-N 3.34Å; S91-V93 PolarHBondContact O-N 3.5Å; V93-L96 PolarHBondContact O-N 2.82Å; V93-C97 PolarHBondContact O-N 2.91Å; V93-C97 VanDerWaalsContact O-N 3.09Å; V93-C97 PolarHBondContact O-SG 3.02Å; V93-C97 VanDerWaalsContact O-SG 3.37Å; V93-F428 HydrophobicContact CG1-CB 4.12Å; V93-F428 HydrophobicContact CG1-CD1 4.18Å; V93-F428 WeakPolarHBondContact CG1-O 3.2Å; V93-F428 HydrophobicContact CG2-CD1 4.36Å; V93-F432 HydrophobicContact CG1-CB 4.01Å; V93-F432 HydrophobicContact CG1-CD2 4.4Å
94	G	93.2	Very high	93.3	Very high	0 Å²	0	18.6 Å²	18.6	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-60.5	-46	177	0	0	0	0	0	113.1	F90 S91 V92 L96 C97 Y98 F432	F90-G94 PolarHBondContact O-N 2.78Å; S91-G94 PolarHBondContact O-N 3.28Å; V92-G94 PolarHBondContact O-N 3.18Å; G94-L96 VanDerWaalsContact C-N 3.33Å; G94-L96 PolarHBondContact O-N 3.42Å; G94-C97 WeakPolarHBondContact O-CB 3.42Å; G94-C97 PolarHBondContact O-N 3.48Å; G94-Y98 PolarHBondContact O-N 3.35Å; G94-F432 VanDerWaalsContact CA-CD2 3.4Å
95	A	92.6	Very high	92.9	Very high	0 Å²	0	18.7 Å²	18.7	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-64.6	-36.7	179.7	0	0	0	0	0	112.2	S91 V92 Y98 A99 W250 I271 M275	S91-A95 VanDerWaalsContact O-CB 3.26Å; S91-A95 WeakPolarHBondContact O-CB 3.31Å; S91-A95 PolarHBondContact O-N 3.36Å; V92-A95 PolarHBondContact O-N 3.34Å; A95-Y98 PolarHBondContact O-N 3.08Å; A95-A99 WeakPolarHBondContact O-CB 3.43Å; A95-A99 PolarHBondContact O-N 3.16Å; A95-W250 VanDerWaalsContact CA-CE3 3.49Å; A95-W250 HydrophobicContact CB-CB 4.31Å; A95-W250 HydrophobicContact CB-CD2 3.7Å; A95-W250 HydrophobicContact CB-CE3 3.6Å; A95-W250 HydrophobicContact CB-CG 4.01Å; A95-W250 HydrophobicContact CB-CZ3 4.26Å; A95-I271 HydrophobicContact CB-CG2 3.44Å; A95-I271 VanDerWaalsContact CB-CG2 3.44Å; A95-M275 HydrophobicContact CB-CG 4.05Å; A95-M275 HydrophobicContact CB-SD 4.19Å
96	L	92.2	Very high	92.3	Very high	43 Å²	43	20.2 Å²	20.2	23%	0.225	11%	0.111	C	C	.	.	H	α-helix	trans	-63.6	-46.5	172.2	-72.2	172.5	0	0	0	111.4	V92 V93 G94 Y98 A99 E100 L424	V92-L96 HydrophobicContact CG1-CD1 4.06Å; V92-L96 VanDerWaalsContact O-CG 3.29Å; V92-L96 WeakPolarHBondContact O-CG 3.21Å; V92-L96 PolarHBondContact O-N 3.19Å; V93-L96 PolarHBondContact O-N 2.82Å; G94-L96 VanDerWaalsContact C-N 3.33Å; G94-L96 PolarHBondContact O-N 3.42Å; L96-Y98 VanDerWaalsContact C-N 3.26Å; L96-Y98 PolarHBondContact O-N 3.39Å; L96-A99 WeakPolarHBondContact O-CB 3.31Å; L96-A99 PolarHBondContact O-N 3.02Å; L96-E100 PolarHBondContact O-N 3.46Å; L96-E100 VanDerWaalsContact O-N 3.13Å; L96-L424 HydrophobicContact CB-CD1 3.8Å; L96-L424 WeakPolarHBondContact O-CD1 3.27Å
97	C	94.2	Very high	91.5	Very high	0 Å²	0	21 Å²	21	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-57.2	-41.2	175.2	-68.6	0	0	0	0	111.9	V93 G94 E100 L101 V405 Q408 P429	V93-C97 PolarHBondContact O-N 2.91Å; V93-C97 VanDerWaalsContact O-N 3.09Å; V93-C97 PolarHBondContact O-SG 3.02Å; V93-C97 VanDerWaalsContact O-SG 3.37Å; G94-C97 WeakPolarHBondContact O-CB 3.42Å; G94-C97 PolarHBondContact O-N 3.48Å; C97-E100 PolarHBondContact O-N 3.36Å; C97-L101 PolarHBondContact O-N 3.33Å; C97-L101 VanDerWaalsContact O-N 3.09Å; C97-V405 HydrophobicContact CB-CG1 4.18Å; C97-V405 HydrophobicContact CB-CG2 3.95Å; C97-Q408 PolarHBondContact O-OE1 3.46Å; C97-P429 VanDerWaalsContact SG-CA 3.58Å
98	Y	92.8	Very high	90.6	Very high	0 Å²	0	21.9 Å²	21.9	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-70.4	-31	174.5	-94.8	-117.9	0	0	0	113.8	G94 A95 L96 E100 L101 G102 S111 Y114 W250 D251 N254 V401 S404 V405	G94-Y98 PolarHBondContact O-N 3.35Å; A95-Y98 PolarHBondContact O-N 3.08Å; L96-Y98 VanDerWaalsContact C-N 3.26Å; L96-Y98 PolarHBondContact O-N 3.39Å; Y98-E100 VanDerWaalsContact C-N 3.25Å; Y98-E100 PolarHBondContact O-N 2.84Å; Y98-L101 HydrophobicContact CD2-CD1 4.45Å; Y98-L101 PolarHBondContact O-N 3.18Å; Y98-G102 PolarHBondContact O-N 3.24Å; Y98-S111 PolarHBondContact OH-OG 2.93Å; Y98-Y114 HydrophobicContact CD1-CD2 4.36Å; Y98-Y114 AromaticContact CD1-CE2 3.83Å; Y98-Y114 HydrophobicContact CD1-CE2 3.83Å; Y98-Y114 HydrophobicContact CE1-CD2 4.11Å; Y98-Y114 AromaticContact CE1-CE2 3.96Å; Y98-Y114 HydrophobicContact CE1-CE2 3.96Å; Y98-W250 VanDerWaalsContact CB-CZ3 3.46Å; Y98-W250 HydrophobicContact CD1-CH2 4.23Å; Y98-W250 AromaticContact CD1-CZ3 3.71Å; Y98-W250 HydrophobicContact CD1-CZ3 3.71Å; Y98-W250 AromaticContact CD2-CH2 3.55Å; Y98-W250 HydrophobicContact CD2-CH2 3.55Å; Y98-W250 AromaticContact CD2-CZ3 3.68Å; Y98-W250 HydrophobicContact CD2-CZ3 3.68Å; Y98-W250 HydrophobicContact CE1-CZ3 4.33Å; Y98-W250 AromaticContact CE2-CH2 3.88Å; Y98-W250 HydrophobicContact CE2-CH2 3.88Å; Y98-W250 HydrophobicContact CE2-CZ3 4.31Å; Y98-W250 AromaticContact CG-CH2 3.76Å; Y98-W250 HydrophobicContact CG-CH2 3.76Å; Y98-W250 AromaticContact CG-CZ3 3.35Å; Y98-W250 HydrophobicContact CG-CZ3 3.35Å; Y98-D251 HydrophobicContact CD1-CB 4.1Å; Y98-D251 HydrophobicContact CE1-CB 4.13Å; Y98-N254 PolarHBondContact O-ND2 2.72Å; Y98-V401 HydrophobicContact CE2-CG1 3.68Å; Y98-V401 WeakPolarHBondContact OH-CA 3.49Å; Y98-S404 WeakPolarHBondContact OH-CB 3.29Å; Y98-S404 PolarHBondContact OH-OG 3.06Å; Y98-S404 VanDerWaalsContact OH-OG 3.1Å; Y98-V405 HydrophobicContact CD2-CG2 4.2Å; Y98-V405 HydrophobicContact CE2-CG2 3.99Å
99	A	91.8	Very high	89.7	Confident	0 Å²	0	22 Å²	22	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-61.1	-39.6	172.1	0	0	0	0	0	110.5	A95 L96 T103 P268 I271 L422	A95-A99 WeakPolarHBondContact O-CB 3.43Å; A95-A99 PolarHBondContact O-N 3.16Å; L96-A99 WeakPolarHBondContact O-CB 3.31Å; L96-A99 PolarHBondContact O-N 3.02Å; A99-T103 VanDerWaalsContact O-CG2 3.3Å; A99-T103 WeakPolarHBondContact O-CG2 3.46Å; A99-T103 PolarHBondContact O-N 3.33Å; A99-T103 PolarHBondContact O-OG1 3.43Å; A99-P268 HydrophobicContact CB-CB 4.32Å; A99-P268 HydrophobicContact CB-CG 4.37Å; A99-I271 HydrophobicContact CB-CD1 3.83Å; A99-L422 HydrophobicContact CB-CD2 3.81Å
100	E	92.6	Very high	89.2	Confident	1 Å²	1	16.4 Å²	16.4	1%	0.005	9%	0.089	C	C	.	.	H	α-helix	trans	-65.2	-47.4	173.2	171.4	170.7	153	0	0	112	L96 C97 Y98 G102 T103 T104 Q408 R412 L422 L424	L96-E100 PolarHBondContact O-N 3.46Å; L96-E100 VanDerWaalsContact O-N 3.13Å; C97-E100 PolarHBondContact O-N 3.36Å; Y98-E100 VanDerWaalsContact C-N 3.25Å; Y98-E100 PolarHBondContact O-N 2.84Å; E100-G102 VanDerWaalsContact C-N 3.33Å; E100-G102 PolarHBondContact O-N 3.43Å; E100-T103 PolarHBondContact O-N 2.83Å; E100-T103 PolarHBondContact O-OG1 3.44Å; E100-T104 WeakPolarHBondContact O-CB 3.37Å; E100-T104 PolarHBondContact O-N 3.29Å; E100-T104 PolarHBondContact O-OG1 3.4Å; E100-Q408 PolarHBondContact OE1-NE2 2.98Å; E100-Q408 PolarHBondContact OE2-NE2 3.38Å; E100-R412 IonicContact OE1-CZ 3.77Å; E100-R412 IonicContact OE1-NE 3.96Å; E100-R412 PolarHBondContact OE1-NE 2.93Å; E100-R412 IonicContact OE1-NH2 2.69Å; E100-R412 PolarHBondContact OE1-NH2 3.07Å; E100-R412 IonicContact OE2-CZ 2.84Å; E100-R412 IonicContact OE2-NH2 3Å; E100-R412 PolarHBondContact OE2-NH2 3.04Å; E100-L422 HydrophobicContact CB-CD2 4.25Å; E100-L422 WeakPolarHBondContact CG-O 3.35Å; E100-L424 HydrophobicContact CB-CD1 4.3Å; E100-L424 WeakPolarHBondContact OE2-CB 3.36Å; E100-L424 PolarHBondContact OE2-N 3.22Å
101	L	92.6	Very high	89	Confident	4 Å²	4	15.6 Å²	15.6	2%	0.021	9%	0.086	C	C	.	.	H	α-helix	trans	-58.9	-44.3	176.5	-77.9	170.3	0	0	0	112	C97 Y98 T103 T104 I105 Y114 Q408	C97-L101 PolarHBondContact O-N 3.33Å; C97-L101 VanDerWaalsContact O-N 3.09Å; Y98-L101 HydrophobicContact CD2-CD1 4.45Å; Y98-L101 PolarHBondContact O-N 3.18Å; L101-T103 PolarHBondContact O-N 3.45Å; L101-T104 PolarHBondContact O-N 3.07Å; L101-I105 HydrophobicContact CD2-CD1 4.43Å; L101-I105 PolarHBondContact O-N 3.32Å; L101-Y114 HydrophobicContact CB-CD1 4.33Å; L101-Y114 HydrophobicContact CB-CD2 3.88Å; L101-Y114 HydrophobicContact CB-CE1 4.27Å; L101-Y114 HydrophobicContact CB-CE2 3.79Å; L101-Y114 HydrophobicContact CB-CG 4.17Å; L101-Y114 HydrophobicContact CD1-CD2 3.85Å; L101-Y114 HydrophobicContact CD1-CE2 4.41Å; L101-Y114 HydrophobicContact CD1-CG 4.28Å; L101-Y114 HydrophobicContact CD2-CG 4.49Å; L101-Y114 HydrophobicContact CG-CD2 4.39Å; L101-Q408 HydrophobicContact CD1-CB 4.14Å; L101-Q408 HydrophobicContact CD2-CB 3.69Å; L101-Q408 HydrophobicContact CD2-CG 3.89Å; L101-Q408 HydrophobicContact CG-CB 3.93Å; L101-Q408 HydrophobicContact CG-CG 3.99Å
102	G	89.5	Confident	88.8	Confident	0 Å²	0	15.7 Å²	15.7	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-70.2	-28.3	179.8	0	0	0	0	0	114.3	Y98 E100 Y114 T257	Y98-G102 PolarHBondContact O-N 3.24Å; E100-G102 VanDerWaalsContact C-N 3.33Å; E100-G102 PolarHBondContact O-N 3.43Å; G102-Y114 WeakPolarHBondContact CA-OH 3.35Å; G102-Y114 PolarHBondContact N-OH 3.35Å; G102-T257 WeakPolarHBondContact O-CG2 3.33Å
103	T	90.9	Very high	88.7	Confident	7 Å²	7	14.1 Å²	14.1	4%	0.043	8%	0.077	C	C	.	.	H	α-helix	trans	-79.3	-21.7	170.8	54.3	0	0	0	0	113.1	A99 E100 L101 L267 P268 L422	A99-T103 VanDerWaalsContact O-CG2 3.3Å; A99-T103 WeakPolarHBondContact O-CG2 3.46Å; A99-T103 PolarHBondContact O-N 3.33Å; A99-T103 PolarHBondContact O-OG1 3.43Å; E100-T103 PolarHBondContact O-N 2.83Å; E100-T103 PolarHBondContact O-OG1 3.44Å; L101-T103 PolarHBondContact O-N 3.45Å; T103-L267 HydrophobicContact CG2-CD2 4.14Å; T103-P268 HydrophobicContact CG2-CG 4.07Å; T103-L422 HydrophobicContact CG2-CB 4.41Å; T103-L422 WeakPolarHBondContact OG1-CB 3.41Å
104	T	90.9	Very high	88.6	Confident	20 Å²	20	13.4 Å²	13.4	12%	0.123	7%	0.073	C	C	.	.	H	α-helix	trans	-91.1	-37.1	179.6	-54	0	0	0	0	112.7	E100 L101 R418 R420	E100-T104 WeakPolarHBondContact O-CB 3.37Å; E100-T104 PolarHBondContact O-N 3.29Å; E100-T104 PolarHBondContact O-OG1 3.4Å; L101-T104 PolarHBondContact O-N 3.07Å; T104-R418 HydrophobicContact CG2-CG 4.19Å; T104-R420 HydrophobicContact CG2-CG 4.03Å
105	I	88.9	Confident	88.7	Confident	2 Å²	2	13.4 Å²	13.4	1%	0.01	7%	0.073	C	C	.	.			trans	-121.5	92.3	-179.8	-54.8	168.9	0	0	0	106.7	L101 K107 Y114 E117 L411	L101-I105 HydrophobicContact CD2-CD1 4.43Å; L101-I105 PolarHBondContact O-N 3.32Å; I105-K107 HydrophobicContact CG2-CB 4.19Å; I105-K107 HydrophobicContact CG2-CD 4.45Å; I105-K107 HydrophobicContact CG2-CG 4.33Å; I105-K107 PolarHBondContact O-N 3.22Å; I105-Y114 HydrophobicContact CB-CD1 3.87Å; I105-Y114 HydrophobicContact CB-CE1 3.89Å; I105-Y114 HydrophobicContact CD1-CD1 3.86Å; I105-Y114 HydrophobicContact CG1-CD1 4.44Å; I105-Y114 HydrophobicContact CG2-CD1 4.03Å; I105-Y114 HydrophobicContact CG2-CE1 4.19Å; I105-E117 HydrophobicContact CD1-CB 3.99Å; I105-E117 HydrophobicContact CD1-CG 4.02Å; I105-E117 HydrophobicContact CG1-CG 4.48Å; I105-L411 HydrophobicContact CD1-CD1 3.84Å
106	T	82	Confident	88.7	Confident	75 Å²	75	15 Å²	15	46%	0.46	8%	0.081	S	C	.	.			trans	-83.2	18.4	-176.5	57.4	0	0	0	0	113.5	T257 E258	T106-T257 HydrophobicContact CG2-CG2 4.42Å; T106-E258 WeakPolarHBondContact O-CG 3.36Å
107	K	80.4	Confident	88.7	Confident	99 Å²	99	15.9 Å²	15.9	43%	0.43	8%	0.084	S	C	.	.			trans	-77.1	138.7	174.3	-65.9	178.6	179.2	170.6	0	110.1	I105 A113 E117 E258	I105-K107 HydrophobicContact CG2-CB 4.19Å; I105-K107 HydrophobicContact CG2-CD 4.45Å; I105-K107 HydrophobicContact CG2-CG 4.33Å; I105-K107 PolarHBondContact O-N 3.22Å; K107-A113 HydrophobicContact CB-CB 4.21Å; K107-E117 IonicContact NZ-OE2 2.71Å; K107-E117 PolarHBondContact NZ-OE2 2.89Å; K107-E258 WeakPolarHBondContact CA-OE1 3.42Å
108	S	74.3	Confident	88.7	Confident	17 Å²	17	16.2 Å²	16.2	12%	0.119	9%	0.087	C	C	.	.	T	Hydrogen-bonded Turn	trans	-67.1	144	171.5	-85	0	0	0	0	112.1	F255 E258	S108-F255 WeakPolarHBondContact CB-O 3.26Å; S108-F255 PolarHBondContact OG-O 2.83Å; S108-E258 PolarHBondContact N-OE1 2.79Å
109	G	76.3	Confident	88.8	Confident	2 Å²	2	19.5 Å²	19.5	2%	0.021	10%	0.101	C	C	.	.	T	Hydrogen-bonded Turn	trans	123.4	-3.3	-178.3	0	0	0	0	0	115.3	S111 Y112 F255	G109-S111 PolarHBondContact O-N 3.38Å; G109-Y112 WeakPolarHBondContact O-CB 3.18Å; G109-Y112 PolarHBondContact O-N 3.25Å; G109-Y112 VanDerWaalsContact O-N 3.1Å; G109-F255 WeakPolarHBondContact O-CE1 3.31Å
110	A	84.8	Confident	88.8	Confident	0 Å²	0	20.9 Å²	20.9	0%	0	12%	0.115	C	C	.	.	T	Hydrogen-bonded Turn	trans	45.7	-121.5	177.3	0	0	0	0	0	112.7	Y112 A113 Y114 N254 F255	A110-Y112 PolarHBondContact O-N 3.02Å; A110-Y112 VanDerWaalsContact O-N 3.13Å; A110-A113 PolarHBondContact O-N 2.93Å; A110-Y114 HydrophobicContact CB-CE2 4.48Å; A110-Y114 WeakPolarHBondContact O-CD1 3.4Å; A110-Y114 VanDerWaalsContact O-CD2 3.26Å; A110-Y114 WeakPolarHBondContact O-CD2 3.2Å; A110-Y114 PolarHBondContact O-N 2.96Å; A110-N254 HydrophobicContact CB-CB 3.77Å; A110-F255 HydrophobicContact CB-CD1 3.82Å; A110-F255 HydrophobicContact CB-CD2 3.47Å; A110-F255 VanDerWaalsContact CB-CD2 3.47Å; A110-F255 HydrophobicContact CB-CE1 3.77Å; A110-F255 HydrophobicContact CB-CE2 3.45Å; A110-F255 VanDerWaalsContact CB-CE2 3.45Å; A110-F255 HydrophobicContact CB-CG 3.69Å; A110-F255 HydrophobicContact CB-CZ 3.61Å
111	S	88.8	Confident	88.7	Confident	0 Å²	0	21.8 Å²	21.8	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-52.9	-36.5	-177.6	-47.2	0	0	0	0	113.5	Y98 G109 I115 S404	Y98-S111 PolarHBondContact OH-OG 2.93Å; G109-S111 PolarHBondContact O-N 3.38Å; S111-I115 VanDerWaalsContact O-CB 3.28Å; S111-I115 WeakPolarHBondContact O-CB 3.3Å; S111-I115 WeakPolarHBondContact O-CD1 3.15Å; S111-I115 VanDerWaalsContact O-CG1 3.22Å; S111-I115 WeakPolarHBondContact O-CG1 3.46Å; S111-I115 PolarHBondContact O-N 2.92Å; S111-S404 WeakPolarHBondContact CB-OG 3.39Å
112	Y	90.6	Very high	88.7	Confident	3 Å²	3	25 Å²	25	1%	0.012	14%	0.139	C	C	.	.	H	α-helix	trans	-63.4	-49.8	178	168.7	-100.8	0	0	0	111.1	G109 A110 Y114 I115 L116 A124 L128 V345 E349 H351	G109-Y112 WeakPolarHBondContact O-CB 3.18Å; G109-Y112 PolarHBondContact O-N 3.25Å; G109-Y112 VanDerWaalsContact O-N 3.1Å; A110-Y112 PolarHBondContact O-N 3.02Å; A110-Y112 VanDerWaalsContact O-N 3.13Å; Y112-Y114 VanDerWaalsContact C-N 3.34Å; Y112-Y114 PolarHBondContact O-N 3.25Å; Y112-I115 PolarHBondContact O-N 3.15Å; Y112-L116 HydrophobicContact CE1-CD2 4.26Å; Y112-L116 VanDerWaalsContact O-CB 3.28Å; Y112-L116 WeakPolarHBondContact O-CB 3.27Å; Y112-L116 PolarHBondContact O-N 3.24Å; Y112-A124 HydrophobicContact CD2-CB 4.06Å; Y112-A124 VanDerWaalsContact CD2-O 3.29Å; Y112-A124 WeakPolarHBondContact CD2-O 3.47Å; Y112-A124 HydrophobicContact CE2-CB 3.76Å; Y112-A124 WeakPolarHBondContact CE2-O 3.49Å; Y112-L128 HydrophobicContact CD2-CB 3.85Å; Y112-L128 HydrophobicContact CD2-CD1 4.46Å; Y112-L128 HydrophobicContact CE2-CB 3.94Å; Y112-L128 HydrophobicContact CE2-CD2 4.06Å; Y112-L128 HydrophobicContact CE2-CG 4.47Å; Y112-V345 HydrophobicContact CD1-CG1 3.83Å; Y112-V345 HydrophobicContact CE1-CG1 3.75Å; Y112-E349 HydrophobicContact CE1-CG 4.01Å; Y112-E349 VanDerWaalsContact OH-CB 3.24Å; Y112-E349 WeakPolarHBondContact OH-CB 3.44Å; Y112-E349 WeakPolarHBondContact OH-CG 3.41Å; Y112-H351 AromaticContact CE2-ND1 3.74Å; Y112-H351 AromaticContact CZ-ND1 3.7Å; Y112-H351 PolarHBondContact OH-CE1 3.17Å; Y112-H351 PolarHBondContact OH-ND1 3.49Å
113	A	89.4	Confident	89	Confident	6 Å²	6	27.5 Å²	27.5	5%	0.05	15%	0.152	C	C	.	.	H	α-helix	trans	-65	-37.7	178.9	0	0	0	0	0	112.1	K107 A110 L116 E117	K107-A113 HydrophobicContact CB-CB 4.21Å; A110-A113 PolarHBondContact O-N 2.93Å; A113-L116 PolarHBondContact O-N 2.93Å; A113-E117 WeakPolarHBondContact O-CB 3.31Å; A113-E117 PolarHBondContact O-N 3.24Å
114	Y	92.6	Very high	89.1	Confident	2 Å²	2	27.2 Å²	27.2	1%	0.008	15%	0.15	C	C	.	.	H	α-helix	trans	-67.2	-43.1	178.4	-55.4	-25.1	0	0	0	112.2	Y98 L101 G102 I105 A110 Y112 A118 N254	Y98-Y114 HydrophobicContact CD1-CD2 4.36Å; Y98-Y114 AromaticContact CD1-CE2 3.83Å; Y98-Y114 HydrophobicContact CD1-CE2 3.83Å; Y98-Y114 HydrophobicContact CE1-CD2 4.11Å; Y98-Y114 AromaticContact CE1-CE2 3.96Å; Y98-Y114 HydrophobicContact CE1-CE2 3.96Å; L101-Y114 HydrophobicContact CB-CD1 4.33Å; L101-Y114 HydrophobicContact CB-CD2 3.88Å; L101-Y114 HydrophobicContact CB-CE1 4.27Å; L101-Y114 HydrophobicContact CB-CE2 3.79Å; L101-Y114 HydrophobicContact CB-CG 4.17Å; L101-Y114 HydrophobicContact CD1-CD2 3.85Å; L101-Y114 HydrophobicContact CD1-CE2 4.41Å; L101-Y114 HydrophobicContact CD1-CG 4.28Å; L101-Y114 HydrophobicContact CD2-CG 4.49Å; L101-Y114 HydrophobicContact CG-CD2 4.39Å; G102-Y114 WeakPolarHBondContact CA-OH 3.35Å; G102-Y114 PolarHBondContact N-OH 3.35Å; I105-Y114 HydrophobicContact CB-CD1 3.87Å; I105-Y114 HydrophobicContact CB-CE1 3.89Å; I105-Y114 HydrophobicContact CD1-CD1 3.86Å; I105-Y114 HydrophobicContact CG1-CD1 4.44Å; I105-Y114 HydrophobicContact CG2-CD1 4.03Å; I105-Y114 HydrophobicContact CG2-CE1 4.19Å; A110-Y114 HydrophobicContact CB-CE2 4.48Å; A110-Y114 WeakPolarHBondContact O-CD1 3.4Å; A110-Y114 VanDerWaalsContact O-CD2 3.26Å; A110-Y114 WeakPolarHBondContact O-CD2 3.2Å; A110-Y114 PolarHBondContact O-N 2.96Å; Y112-Y114 VanDerWaalsContact C-N 3.34Å; Y112-Y114 PolarHBondContact O-N 3.25Å; Y114-A118 VanDerWaalsContact O-CB 3.29Å; Y114-A118 WeakPolarHBondContact O-CB 3.48Å; Y114-A118 PolarHBondContact O-N 3.38Å; Y114-N254 HydrophobicContact CE2-CB 4.43Å; Y114-N254 WeakPolarHBondContact OH-CB 3.26Å; Y114-N254 PolarHBondContact OH-ND2 2.85Å
115	I	94.6	Very high	89.2	Confident	0 Å²	0	26.5 Å²	26.5	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-68.5	-38.5	176.7	-72.3	169.5	0	0	0	110.7	S111 Y112 A118 F119 G120 I123 A124 R127 F400 L403	S111-I115 VanDerWaalsContact O-CB 3.28Å; S111-I115 WeakPolarHBondContact O-CB 3.3Å; S111-I115 WeakPolarHBondContact O-CD1 3.15Å; S111-I115 VanDerWaalsContact O-CG1 3.22Å; S111-I115 WeakPolarHBondContact O-CG1 3.46Å; S111-I115 PolarHBondContact O-N 2.92Å; Y112-I115 PolarHBondContact O-N 3.15Å; I115-A118 PolarHBondContact O-N 3.39Å; I115-F119 HydrophobicContact CG2-CD2 4.21Å; I115-F119 PolarHBondContact O-N 3.49Å; I115-G120 PolarHBondContact O-N 2.93Å; I115-I123 HydrophobicContact CG2-CB 3.93Å; I115-I123 HydrophobicContact CG2-CG2 3.52Å; I115-A124 HydrophobicContact CG2-CB 4.23Å; I115-R127 HydrophobicContact CD1-CB 4Å; I115-R127 HydrophobicContact CD1-CG 3.83Å; I115-F400 HydrophobicContact CD1-CD1 4.09Å; I115-L403 HydrophobicContact CD1-CD2 4.23Å; I115-L403 HydrophobicContact CD1-CG 4.39Å
116	L	93.1	Very high	89.5	Confident	34 Å²	34	27.4 Å²	27.4	18%	0.178	15%	0.15	C	C	.	.	H	α-helix	trans	-59.7	-47.9	176.2	-178.7	60.8	0	0	0	111.6	Y112 A113 G120 A124 E349	Y112-L116 HydrophobicContact CE1-CD2 4.26Å; Y112-L116 VanDerWaalsContact O-CB 3.28Å; Y112-L116 WeakPolarHBondContact O-CB 3.27Å; Y112-L116 PolarHBondContact O-N 3.24Å; A113-L116 PolarHBondContact O-N 2.93Å; L116-G120 VanDerWaalsContact O-CA 3.24Å; L116-G120 WeakPolarHBondContact O-CA 3.1Å; L116-G120 PolarHBondContact O-N 3.48Å; L116-A124 HydrophobicContact CB-CB 3.7Å; L116-A124 HydrophobicContact CD1-CB 3.78Å; L116-A124 HydrophobicContact CG-CB 4.33Å; L116-E349 HydrophobicContact CD2-CG 4.31Å
117	E	92.3	Very high	90	Very high	62 Å²	62	24.1 Å²	24.1	29%	0.29	13%	0.129	S	C	.	.	H	α-helix	trans	-67.8	-37.5	179.1	-167	85.9	173.5	0	0	112.2	I105 K107 A113 R418	I105-E117 HydrophobicContact CD1-CB 3.99Å; I105-E117 HydrophobicContact CD1-CG 4.02Å; I105-E117 HydrophobicContact CG1-CG 4.48Å; K107-E117 IonicContact NZ-OE2 2.71Å; K107-E117 PolarHBondContact NZ-OE2 2.89Å; A113-E117 WeakPolarHBondContact O-CB 3.31Å; A113-E117 PolarHBondContact O-N 3.24Å; E117-R418 IonicContact OE1-CZ 3.16Å; E117-R418 IonicContact OE1-NH1 2.84Å; E117-R418 PolarHBondContact OE1-NH1 3.44Å; E117-R418 IonicContact OE1-NH2 3.74Å; E117-R418 PolarHBondContact OE1-NH2 3.48Å
118	A	94	Very high	90.6	Very high	6 Å²	6	19.4 Å²	19.4	5%	0.05	11%	0.108	C	C	.	.	H	α-helix	trans	-81.5	-44.5	-176.5	0	0	0	0	0	113.8	Y114 I115 Y410 L411	Y114-A118 VanDerWaalsContact O-CB 3.29Å; Y114-A118 WeakPolarHBondContact O-CB 3.48Å; Y114-A118 PolarHBondContact O-N 3.38Å; I115-A118 PolarHBondContact O-N 3.39Å; A118-Y410 HydrophobicContact CB-CD1 4.39Å; A118-Y410 WeakPolarHBondContact O-CD1 3.35Å; A118-Y410 WeakPolarHBondContact O-CE1 3.17Å; A118-L411 HydrophobicContact CB-CD1 4.17Å; A118-L411 HydrophobicContact CB-CG 4.12Å
119	F	94.8	Very high	91.5	Very high	70 Å²	70	20.5 Å²	20.5	31%	0.307	11%	0.11	S	C	.	.	H	α-helix	trans	-120.1	-5.9	-168.4	-57.3	-65	0	0	0	114.2	I115 I123 L403 V406 Y410	I115-F119 HydrophobicContact CG2-CD2 4.21Å; I115-F119 PolarHBondContact O-N 3.49Å; F119-I123 HydrophobicContact CB-CB 3.97Å; F119-I123 HydrophobicContact CB-CG1 3.98Å; F119-I123 HydrophobicContact CB-CG2 4.37Å; F119-L403 HydrophobicContact CD2-CD1 4.48Å; F119-L403 HydrophobicContact CD2-CG 4.47Å; F119-L403 HydrophobicContact CE2-CD1 3.85Å; F119-L403 HydrophobicContact CE2-CG 4.03Å; F119-L403 WeakPolarHBondContact CE2-O 3.03Å; F119-L403 HydrophobicContact CZ-CD1 4.14Å; F119-V406 HydrophobicContact CZ-CB 4.47Å; F119-V406 HydrophobicContact CZ-CG1 4.11Å; F119-Y410 HydrophobicContact CE1-CG 4.43Å
120	G	91.9	Very high	92.4	Very high	28 Å²	28	20.4 Å²	20.4	29%	0.289	11%	0.109	S	C	.	.			trans	86.1	-177.7	178.6	0	0	0	0	0	114.8	I115 L116 F122 A124	I115-G120 PolarHBondContact O-N 2.93Å; L116-G120 VanDerWaalsContact O-CA 3.24Å; L116-G120 WeakPolarHBondContact O-CA 3.1Å; L116-G120 PolarHBondContact O-N 3.48Å; G120-F122 PolarHBondContact O-N 3.24Å; G120-A124 WeakPolarHBondContact O-CB 3.16Å; G120-A124 PolarHBondContact O-N 3.07Å
121	G	90.7	Very high	92.7	Very high	21 Å²	21	20.4 Å²	20.4	22%	0.216	11%	0.109	C	C	.	.	H	α-helix	trans	-62.5	-35.4	-167.4	0	0	0	0	0	115.3	A124 F125 H351	G121-A124 PolarHBondContact O-N 3.13Å; G121-F125 WeakPolarHBondContact O-CB 3.33Å; G121-F125 PolarHBondContact O-N 3.41Å; G121-H351 PolarHBondContact O-CE1 3.24Å
122	F	93	Very high	92.8	Very high	72 Å²	72	20.6 Å²	20.6	32%	0.316	11%	0.11	S	C	.	.	H	α-helix	trans	-62.3	-54.1	-177.7	175.8	-114.6	0	0	0	112.6	G120 A124 F125 I126 V462 Y465 F466	G120-F122 PolarHBondContact O-N 3.24Å; F122-A124 VanDerWaalsContact C-N 3.29Å; F122-A124 PolarHBondContact O-N 3.17Å; F122-F125 PolarHBondContact O-N 3.21Å; F122-I126 HydrophobicContact CE2-CD1 4.31Å; F122-I126 HydrophobicContact CE2-CG1 4.24Å; F122-I126 HydrophobicContact CZ-CG1 4.28Å; F122-I126 WeakPolarHBondContact O-CG1 3.4Å; F122-I126 PolarHBondContact O-N 3.24Å; F122-V462 HydrophobicContact CE2-CG1 4.27Å; F122-V462 HydrophobicContact CE2-CG2 4.23Å; F122-V462 HydrophobicContact CZ-CG1 4.34Å; F122-V462 HydrophobicContact CZ-CG2 3.95Å; F122-Y465 HydrophobicContact CB-CE1 3.97Å; F122-Y465 HydrophobicContact CB-CE2 4.48Å; F122-Y465 AromaticContact CD2-CD1 3.43Å; F122-Y465 HydrophobicContact CD2-CD1 3.43Å; F122-Y465 VanDerWaalsContact CD2-CD1 3.43Å; F122-Y465 HydrophobicContact CD2-CD2 4.4Å; F122-Y465 AromaticContact CD2-CE1 3.68Å; F122-Y465 HydrophobicContact CD2-CE1 3.68Å; F122-Y465 AromaticContact CD2-CG 3.8Å; F122-Y465 HydrophobicContact CD2-CG 3.8Å; F122-Y465 HydrophobicContact CE2-CD1 4.09Å; F122-Y465 HydrophobicContact CE2-CG 4.37Å; F122-Y465 HydrophobicContact CG-CD1 4.45Å; F122-Y465 HydrophobicContact CG-CE1 4.29Å; F122-Y465 PolarHBondContact N-OH 2.93Å; F122-F466 HydrophobicContact CE2-CE2 4.49Å
123	I	94.4	Very high	92.9	Very high	52 Å²	52	22 Å²	22	27%	0.267	12%	0.117	S	C	.	.	H	α-helix	trans	-68.4	-34.7	-178.5	-54.1	-61.4	0	0	0	110.5	I115 F119 I126 R127 L403	I115-I123 HydrophobicContact CG2-CB 3.93Å; I115-I123 HydrophobicContact CG2-CG2 3.52Å; F119-I123 HydrophobicContact CB-CB 3.97Å; F119-I123 HydrophobicContact CB-CG1 3.98Å; F119-I123 HydrophobicContact CB-CG2 4.37Å; I123-I126 PolarHBondContact O-N 3.21Å; I123-R127 PolarHBondContact O-N 3.45Å; I123-L403 HydrophobicContact CG2-CD2 3.6Å
124	A	93.3	Very high	93.1	Very high	0 Å²	0	21.8 Å²	21.8	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-63.1	-41.4	173.8	0	0	0	0	0	112.3	Y112 I115 L116 G120 G121 F122 R127 L128	Y112-A124 HydrophobicContact CD2-CB 4.06Å; Y112-A124 VanDerWaalsContact CD2-O 3.29Å; Y112-A124 WeakPolarHBondContact CD2-O 3.47Å; Y112-A124 HydrophobicContact CE2-CB 3.76Å; Y112-A124 WeakPolarHBondContact CE2-O 3.49Å; I115-A124 HydrophobicContact CG2-CB 4.23Å; L116-A124 HydrophobicContact CB-CB 3.7Å; L116-A124 HydrophobicContact CD1-CB 3.78Å; L116-A124 HydrophobicContact CG-CB 4.33Å; G120-A124 WeakPolarHBondContact O-CB 3.16Å; G120-A124 PolarHBondContact O-N 3.07Å; G121-A124 PolarHBondContact O-N 3.13Å; F122-A124 VanDerWaalsContact C-N 3.29Å; F122-A124 PolarHBondContact O-N 3.17Å; A124-R127 WeakPolarHBondContact O-CB 3.18Å; A124-R127 PolarHBondContact O-N 3.11Å; A124-L128 WeakPolarHBondContact O-CB 3.41Å; A124-L128 PolarHBondContact O-N 2.89Å
125	F	93.3	Very high	93.1	Very high	6 Å²	6	21.9 Å²	21.9	3%	0.026	12%	0.116	C	C	.	.	H	α-helix	trans	-61.8	-45.8	173.6	175.2	-85.4	0	0	0	111.4	G121 F122 R127 L128 W129 H351 G461 F464 Y465 V469	G121-F125 WeakPolarHBondContact O-CB 3.33Å; G121-F125 PolarHBondContact O-N 3.41Å; F122-F125 PolarHBondContact O-N 3.21Å; F125-R127 VanDerWaalsContact C-N 3.3Å; F125-R127 PolarHBondContact O-N 2.78Å; F125-L128 WeakPolarHBondContact O-CB 3.42Å; F125-L128 PolarHBondContact O-N 3.28Å; F125-L128 VanDerWaalsContact O-N 3.12Å; F125-W129 HydrophobicContact CD1-CB 4.47Å; F125-W129 HydrophobicContact CE1-CB 4.13Å; F125-W129 HydrophobicContact CE1-CD2 4.23Å; F125-W129 HydrophobicContact CE1-CE3 4.03Å; F125-W129 HydrophobicContact CE1-CG 4.31Å; F125-W129 HydrophobicContact CE2-CE3 4.43Å; F125-W129 HydrophobicContact CZ-CD2 4.24Å; F125-W129 AromaticContact CZ-CE3 3.58Å; F125-W129 HydrophobicContact CZ-CE3 3.58Å; F125-W129 HydrophobicContact CZ-CZ3 4.11Å; F125-W129 VanDerWaalsContact O-CB 3.31Å; F125-W129 WeakPolarHBondContact O-CB 3.5Å; F125-W129 PolarHBondContact O-N 3.27Å; F125-H351 HydrophobicContact CD2-CB 3.99Å; F125-H351 WeakPolarHBondContact CD2-O 3.47Å; F125-H351 WeakPolarHBondContact CE2-O 3.49Å; F125-G461 WeakPolarHBondContact CE1-O 3.3Å; F125-F464 HydrophobicContact CE1-CB 4.49Å; F125-F464 HydrophobicContact CZ-CB 4.11Å; F125-Y465 HydrophobicContact CB-CD2 3.44Å; F125-Y465 VanDerWaalsContact CB-CD2 3.44Å; F125-Y465 HydrophobicContact CB-CE2 3.83Å; F125-Y465 HydrophobicContact CB-CG 4.47Å; F125-Y465 AromaticContact CD1-CD2 3.82Å; F125-Y465 HydrophobicContact CD1-CD2 3.82Å; F125-Y465 HydrophobicContact CD1-CG 4.18Å; F125-Y465 AromaticContact CD2-CD2 3.92Å; F125-Y465 HydrophobicContact CD2-CD2 3.92Å; F125-Y465 AromaticContact CG-CD2 3.44Å; F125-Y465 HydrophobicContact CG-CD2 3.44Å; F125-Y465 VanDerWaalsContact CG-CD2 3.44Å; F125-Y465 HydrophobicContact CG-CE2 4.29Å; F125-Y465 HydrophobicContact CG-CG 4.26Å; F125-V469 HydrophobicContact CD2-CG2 4.03Å; F125-V469 HydrophobicContact CE2-CG2 4.23Å
126	I	94.4	Very high	92.9	Very high	20 Å²	20	23.3 Å²	23.3	10%	0.103	12%	0.123	C	C	.	.	H	α-helix	trans	-62.3	-40.2	178.7	-60.1	-64.6	0	0	0	110.8	F122 I123 L128 W129 V130 F400 A458 V462	F122-I126 HydrophobicContact CE2-CD1 4.31Å; F122-I126 HydrophobicContact CE2-CG1 4.24Å; F122-I126 HydrophobicContact CZ-CG1 4.28Å; F122-I126 WeakPolarHBondContact O-CG1 3.4Å; F122-I126 PolarHBondContact O-N 3.24Å; I123-I126 PolarHBondContact O-N 3.21Å; I126-L128 PolarHBondContact O-N 3.24Å; I126-W129 PolarHBondContact O-N 2.98Å; I126-V130 WeakPolarHBondContact O-CG2 3.3Å; I126-V130 PolarHBondContact O-N 2.96Å; I126-F400 HydrophobicContact CG2-CZ 4.07Å; I126-A458 HydrophobicContact CG2-CB 4.33Å; I126-V462 HydrophobicContact CD1-CG2 3.93Å
127	R	93.5	Very high	93	Very high	7 Å²	7	21.7 Å²	21.7	3%	0.026	12%	0.115	C	C	.	.	H	α-helix	trans	-57.5	-47.3	171.8	169.4	67.9	-174.6	81.3	-1.6	111.9	I115 I123 A124 F125 S131 F400	I115-R127 HydrophobicContact CD1-CB 4Å; I115-R127 HydrophobicContact CD1-CG 3.83Å; I123-R127 PolarHBondContact O-N 3.45Å; A124-R127 WeakPolarHBondContact O-CB 3.18Å; A124-R127 PolarHBondContact O-N 3.11Å; F125-R127 VanDerWaalsContact C-N 3.3Å; F125-R127 PolarHBondContact O-N 2.78Å; R127-S131 PolarHBondContact NH1-OG 3.47Å; R127-S131 PolarHBondContact O-N 3.36Å; R127-F400 HydrophobicContact CB-CD1 3.83Å; R127-F400 HydrophobicContact CB-CE1 3.84Å; R127-F400 HydrophobicContact CB-CG 4.48Å; R127-F400 HydrophobicContact CG-CD1 4.17Å; R127-F400 HydrophobicContact CG-CG 4.43Å
128	L	92.4	Very high	93.1	Very high	0 Å²	0	18.8 Å²	18.8	0%	0	10%	0.101	C	C	.	.	H	α-helix	trans	-63.7	-49	179.8	-178.9	65.5	0	0	0	110.5	Y112 A124 F125 I126 V130 S131 L132 L342 H351 L352	Y112-L128 HydrophobicContact CD2-CB 3.85Å; Y112-L128 HydrophobicContact CD2-CD1 4.46Å; Y112-L128 HydrophobicContact CE2-CB 3.94Å; Y112-L128 HydrophobicContact CE2-CD2 4.06Å; Y112-L128 HydrophobicContact CE2-CG 4.47Å; A124-L128 WeakPolarHBondContact O-CB 3.41Å; A124-L128 PolarHBondContact O-N 2.89Å; F125-L128 WeakPolarHBondContact O-CB 3.42Å; F125-L128 PolarHBondContact O-N 3.28Å; F125-L128 VanDerWaalsContact O-N 3.12Å; I126-L128 PolarHBondContact O-N 3.24Å; L128-V130 PolarHBondContact O-N 3.24Å; L128-S131 WeakPolarHBondContact O-CA 3.4Å; L128-S131 VanDerWaalsContact O-CB 3.3Å; L128-S131 WeakPolarHBondContact O-CB 3.35Å; L128-S131 PolarHBondContact O-N 3Å; L128-L132 HydrophobicContact CD1-CD1 3.96Å; L128-L132 HydrophobicContact CD1-CG 4.22Å; L128-L132 HydrophobicContact CG-CD1 3.94Å; L128-L132 HydrophobicContact CG-CG 4.48Å; L128-L132 VanDerWaalsContact O-CG 3.3Å; L128-L132 WeakPolarHBondContact O-CG 3.24Å; L128-L132 PolarHBondContact O-N 3.37Å; L128-L342 HydrophobicContact CD1-CD1 3.77Å; L128-L342 HydrophobicContact CD1-CD2 4.22Å; L128-L342 HydrophobicContact CD1-CG 3.66Å; L128-H351 HydrophobicContact CD2-CB 4.02Å; L128-L352 HydrophobicContact CD2-CD1 3.95Å; L128-L352 HydrophobicContact CD2-CD2 4.23Å; L128-L352 HydrophobicContact CD2-CG 3.81Å; L128-L352 HydrophobicContact CG-CD1 4.47Å
129	W	93.9	Very high	93	Very high	39 Å²	39	19.3 Å²	19.3	15%	0.148	10%	0.104	C	C	.	.	H	α-helix	trans	-52.9	-50.9	177.8	-171.9	-101.6	0	0	0	112	F125 I126 S131 L132 L133 I457 S460 F464	F125-W129 HydrophobicContact CD1-CB 4.47Å; F125-W129 HydrophobicContact CE1-CB 4.13Å; F125-W129 HydrophobicContact CE1-CD2 4.23Å; F125-W129 HydrophobicContact CE1-CE3 4.03Å; F125-W129 HydrophobicContact CE1-CG 4.31Å; F125-W129 HydrophobicContact CE2-CE3 4.43Å; F125-W129 HydrophobicContact CZ-CD2 4.24Å; F125-W129 AromaticContact CZ-CE3 3.58Å; F125-W129 HydrophobicContact CZ-CE3 3.58Å; F125-W129 HydrophobicContact CZ-CZ3 4.11Å; F125-W129 VanDerWaalsContact O-CB 3.31Å; F125-W129 WeakPolarHBondContact O-CB 3.5Å; F125-W129 PolarHBondContact O-N 3.27Å; I126-W129 PolarHBondContact O-N 2.98Å; W129-S131 VanDerWaalsContact C-N 3.32Å; W129-S131 PolarHBondContact O-N 3.43Å; W129-L132 PolarHBondContact O-N 3.2Å; W129-L133 HydrophobicContact CD2-CD1 3.94Å; W129-L133 HydrophobicContact CG-CD1 4.28Å; W129-L133 HydrophobicContact CH2-CD1 4.39Å; W129-L133 HydrophobicContact CZ2-CD1 3.62Å; W129-L133 WeakPolarHBondContact O-CB 3.4Å; W129-L133 WeakPolarHBondContact O-CG 3.29Å; W129-L133 PolarHBondContact O-N 3.48Å; W129-I457 PolarHBondContact NE1-O 2.94Å; W129-S460 PolarHBondContact NE1-OG 3.22Å; W129-S460 VanDerWaalsContact NE1-OG 3.13Å; W129-F464 HydrophobicContact CH2-CB 3.99Å; W129-F464 AromaticContact CH2-CD1 3.75Å; W129-F464 HydrophobicContact CH2-CD1 3.75Å; W129-F464 AromaticContact CH2-CD2 3.71Å; W129-F464 HydrophobicContact CH2-CD2 3.71Å; W129-F464 HydrophobicContact CH2-CE1 4.1Å; W129-F464 HydrophobicContact CH2-CE2 4.07Å; W129-F464 AromaticContact CH2-CG 3.53Å; W129-F464 HydrophobicContact CH2-CG 3.53Å; W129-F464 HydrophobicContact CH2-CZ 4.25Å; W129-F464 HydrophobicContact CZ2-CB 4.43Å; W129-F464 AromaticContact CZ2-CD2 3.7Å; W129-F464 HydrophobicContact CZ2-CD2 3.7Å; W129-F464 HydrophobicContact CZ2-CE2 4.02Å; W129-F464 AromaticContact CZ2-CG 3.98Å; W129-F464 HydrophobicContact CZ2-CG 3.98Å; W129-F464 HydrophobicContact CZ3-CB 4.13Å; W129-F464 HydrophobicContact CZ3-CD1 4.3Å; W129-F464 HydrophobicContact CZ3-CG 4.12Å
130	V	93.7	Very high	93	Very high	0 Å²	0	16 Å²	16	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-67.6	-33.9	178.2	176.8	0	0	0	0	111.9	I126 L128 V134 V135 F400 A458	I126-V130 WeakPolarHBondContact O-CG2 3.3Å; I126-V130 PolarHBondContact O-N 2.96Å; L128-V130 PolarHBondContact O-N 3.24Å; V130-V134 HydrophobicContact CG1-CB 4.15Å; V130-V134 HydrophobicContact CG1-CG2 4.25Å; V130-V134 WeakPolarHBondContact O-CA 3.39Å; V130-V134 WeakPolarHBondContact O-CB 3.38Å; V130-V134 PolarHBondContact O-N 2.97Å; V130-V135 HydrophobicContact CG1-CG2 4.32Å; V130-V135 PolarHBondContact O-N 3.32Å; V130-V135 VanDerWaalsContact O-N 3.11Å; V130-F400 HydrophobicContact CB-CD2 4.41Å; V130-F400 HydrophobicContact CB-CE2 3.59Å; V130-F400 HydrophobicContact CB-CZ 4.22Å; V130-F400 HydrophobicContact CG1-CD2 4.27Å; V130-F400 HydrophobicContact CG1-CE2 3.7Å; V130-F400 HydrophobicContact CG2-CE2 3.77Å; V130-F400 HydrophobicContact CG2-CZ 4.04Å; V130-A458 HydrophobicContact CG2-CB 3.51Å
131	S	91.9	Very high	93.3	Very high	0 Å²	0	14.7 Å²	14.7	0%	0	8%	0.076	C	C	.	.	I	π-helix	trans	-60.2	-49.6	175.1	-128.3	0	0	0	0	111.8	R127 L128 W129 V135 E136	R127-S131 PolarHBondContact NH1-OG 3.47Å; R127-S131 PolarHBondContact O-N 3.36Å; L128-S131 WeakPolarHBondContact O-CA 3.4Å; L128-S131 VanDerWaalsContact O-CB 3.3Å; L128-S131 WeakPolarHBondContact O-CB 3.35Å; L128-S131 PolarHBondContact O-N 3Å; W129-S131 VanDerWaalsContact C-N 3.32Å; W129-S131 PolarHBondContact O-N 3.43Å; S131-V135 PolarHBondContact O-N 3.03Å; S131-E136 WeakPolarHBondContact O-CG 3.37Å; S131-E136 PolarHBondContact O-N 2.88Å
132	L	91.4	Very high	93.5	Very high	5 Å²	5	13.7 Å²	13.7	3%	0.026	7%	0.066	C	C	.	.	I	π-helix	trans	-76.2	-29.8	-172	-59.7	175.7	0	0	0	112.6	L128 W129 P137 L342 F343 L352	L128-L132 HydrophobicContact CD1-CD1 3.96Å; L128-L132 HydrophobicContact CD1-CG 4.22Å; L128-L132 HydrophobicContact CG-CD1 3.94Å; L128-L132 HydrophobicContact CG-CG 4.48Å; L128-L132 VanDerWaalsContact O-CG 3.3Å; L128-L132 WeakPolarHBondContact O-CG 3.24Å; L128-L132 PolarHBondContact O-N 3.37Å; W129-L132 PolarHBondContact O-N 3.2Å; L132-P137 WeakPolarHBondContact O-CD 3.42Å; L132-P137 WeakPolarHBondContact O-CG 3.41Å; L132-L342 HydrophobicContact CD2-CB 4.31Å; L132-L342 HydrophobicContact CD2-CD2 3.8Å; L132-L342 HydrophobicContact CD2-CG 4Å; L132-F343 HydrophobicContact CB-CE1 4.27Å; L132-F343 HydrophobicContact CB-CZ 4.17Å; L132-F343 HydrophobicContact CD1-CD1 3.92Å; L132-F343 HydrophobicContact CD1-CE1 3.71Å; L132-F343 HydrophobicContact CD1-CZ 4.31Å; L132-F343 HydrophobicContact CD2-CD1 4.08Å; L132-F343 HydrophobicContact CD2-CD2 4.02Å; L132-F343 HydrophobicContact CD2-CE1 3.79Å; L132-F343 HydrophobicContact CD2-CE2 3.7Å; L132-F343 HydrophobicContact CD2-CG 4.18Å; L132-F343 HydrophobicContact CD2-CZ 3.57Å; L132-F343 HydrophobicContact CG-CE1 4.11Å; L132-F343 HydrophobicContact CG-CZ 4.2Å; L132-L352 HydrophobicContact CD1-CD1 3.7Å; L132-L352 HydrophobicContact CD1-CD2 3.94Å; L132-L352 HydrophobicContact CD1-CG 4.44Å
133	L	92.9	Very high	93.5	Very high	32 Å²	32	10.9 Å²	10.9	17%	0.168	5%	0.054	C	C	.	.	I	π-helix	trans	-94.6	-29.4	-179.5	-65.1	-174.5	0	0	0	113.8	W129 F372 M376 Y380 I457	W129-L133 HydrophobicContact CD2-CD1 3.94Å; W129-L133 HydrophobicContact CG-CD1 4.28Å; W129-L133 HydrophobicContact CH2-CD1 4.39Å; W129-L133 HydrophobicContact CZ2-CD1 3.62Å; W129-L133 WeakPolarHBondContact O-CB 3.4Å; W129-L133 WeakPolarHBondContact O-CG 3.29Å; W129-L133 PolarHBondContact O-N 3.48Å; L133-F372 HydrophobicContact CD2-CE1 4.26Å; L133-F372 HydrophobicContact CD2-CZ 3.79Å; L133-M376 HydrophobicContact CD2-SD 4.11Å; L133-Y380 WeakPolarHBondContact O-CE2 3.38Å; L133-Y380 PolarHBondContact O-OH 3.18Å; L133-I457 HydrophobicContact CB-CG2 4.2Å; L133-I457 HydrophobicContact CD1-CG2 4.27Å
134	V	92.5	Very high	93.6	Very high	2 Å²	2	8.4 Å²	8.4	1%	0.012	4%	0.041	C	C	.	.	I	π-helix	trans	-118.3	-62.8	-174.1	-173.6	0	0	0	0	110.8	V130 T138 I457	V130-V134 HydrophobicContact CG1-CB 4.15Å; V130-V134 HydrophobicContact CG1-CG2 4.25Å; V130-V134 WeakPolarHBondContact O-CA 3.39Å; V130-V134 WeakPolarHBondContact O-CB 3.38Å; V130-V134 PolarHBondContact O-N 2.97Å; V134-T138 WeakPolarHBondContact O-CB 3.47Å; V134-T138 PolarHBondContact O-N 3.29Å; V134-T138 PolarHBondContact O-OG1 2.97Å; V134-I457 HydrophobicContact CG2-CB 4.18Å; V134-I457 HydrophobicContact CG2-CD1 3.92Å; V134-I457 HydrophobicContact CG2-CG2 3.6Å
135	V	92.1	Very high	93.7	Very high	4 Å²	4	8.6 Å²	8.6	2%	0.024	4%	0.042	C	C	.	.	I	π-helix	trans	-63.8	-54.7	-165.5	-178.4	0	0	0	0	112.1	V130 S131 S139 F393 Y397	V130-V135 HydrophobicContact CG1-CG2 4.32Å; V130-V135 PolarHBondContact O-N 3.32Å; V130-V135 VanDerWaalsContact O-N 3.11Å; S131-V135 PolarHBondContact O-N 3.03Å; V135-S139 VanDerWaalsContact O-CB 3.31Å; V135-S139 WeakPolarHBondContact O-CB 3.44Å; V135-S139 PolarHBondContact O-N 3.44Å; V135-S139 VanDerWaalsContact O-N 3.11Å; V135-F393 HydrophobicContact CB-CD2 4.49Å; V135-F393 HydrophobicContact CG1-CD2 3.77Å; V135-F393 HydrophobicContact CG1-CE2 3.45Å; V135-F393 VanDerWaalsContact CG1-CE2 3.45Å; V135-F393 HydrophobicContact CG1-CZ 4.41Å; V135-F393 WeakPolarHBondContact O-CD2 3.43Å; V135-Y397 HydrophobicContact CG1-CD2 3.99Å
136	E	91.8	Very high	93.7	Very high	30 Å²	30	8.5 Å²	8.5	14%	0.14	4%	0.042	C	C	.	.	H	α-helix	trans	-66.7	-50.8	-177.1	-55.8	-61.1	150.1	0	0	112	S131 T138 S139 Q140	S131-E136 WeakPolarHBondContact O-CG 3.37Å; S131-E136 PolarHBondContact O-N 2.88Å; E136-T138 PolarHBondContact O-N 3.03Å; E136-S139 PolarHBondContact O-N 3.37Å; E136-Q140 VanDerWaalsContact O-CG 3.25Å; E136-Q140 WeakPolarHBondContact O-CG 3.33Å; E136-Q140 PolarHBondContact O-N 3Å
137	P	94.5	Very high	93.6	Very high	0 Å²	0	8.6 Å²	8.6	0%	0	4%	0.042	C	C	.	.	H	α-helix	trans	-65.4	-38.4	-177.3	-23.4	36.8	0	0	0	113.1	L132 Q140 A141 M376 T377 Y380	L132-P137 WeakPolarHBondContact O-CD 3.42Å; L132-P137 WeakPolarHBondContact O-CG 3.41Å; P137-Q140 PolarHBondContact O-N 3.45Å; P137-A141 WeakPolarHBondContact O-CB 3.38Å; P137-A141 PolarHBondContact O-N 2.77Å; P137-M376 HydrophobicContact CB-CB 3.83Å; P137-M376 HydrophobicContact CG-CB 3.65Å; P137-T377 WeakPolarHBondContact CA-OG1 3.45Å; P137-Y380 HydrophobicContact CB-CD2 3.66Å; P137-Y380 HydrophobicContact CB-CE2 3.89Å
138	T	94.3	Very high	93.7	Very high	0 Å²	0	8.2 Å²	8.2	0%	0	4%	0.041	C	C	.	.	H	α-helix	trans	-66.3	-44.5	179	-58.3	0	0	0	0	111	V134 E136 Q140 A141 I142 Y380 L389 F393	V134-T138 WeakPolarHBondContact O-CB 3.47Å; V134-T138 PolarHBondContact O-N 3.29Å; V134-T138 PolarHBondContact O-OG1 2.97Å; E136-T138 PolarHBondContact O-N 3.03Å; T138-Q140 PolarHBondContact O-N 3.46Å; T138-A141 PolarHBondContact O-N 2.73Å; T138-I142 HydrophobicContact CG2-CD1 4.07Å; T138-I142 WeakPolarHBondContact O-CD1 3.46Å; T138-I142 VanDerWaalsContact O-CG1 3.27Å; T138-I142 WeakPolarHBondContact O-CG1 3.28Å; T138-I142 PolarHBondContact O-N 3.05Å; T138-Y380 WeakPolarHBondContact OG1-CE1 3.21Å; T138-L389 HydrophobicContact CG2-CB 3.71Å; T138-L389 HydrophobicContact CG2-CD2 3.99Å; T138-L389 HydrophobicContact CG2-CG 4.43Å; T138-L389 WeakPolarHBondContact CG2-O 3.29Å; T138-F393 HydrophobicContact CG2-CB 3.92Å
139	S	93.2	Very high	93.7	Very high	18 Å²	18	9.2 Å²	9.2	13%	0.126	5%	0.046	C	C	.	.	H	α-helix	trans	-59.5	-46.5	175.9	-176.5	0	0	0	0	111.5	V135 E136 A141 I142 I143	V135-S139 VanDerWaalsContact O-CB 3.31Å; V135-S139 WeakPolarHBondContact O-CB 3.44Å; V135-S139 PolarHBondContact O-N 3.44Å; V135-S139 VanDerWaalsContact O-N 3.11Å; E136-S139 PolarHBondContact O-N 3.37Å; S139-A141 VanDerWaalsContact C-N 3.35Å; S139-A141 PolarHBondContact O-N 3.45Å; S139-I142 PolarHBondContact O-N 3.05Å; S139-I143 WeakPolarHBondContact O-CD1 3.37Å; S139-I143 VanDerWaalsContact O-CG1 3.25Å; S139-I143 WeakPolarHBondContact O-CG1 3.41Å; S139-I143 PolarHBondContact O-N 3.39Å
140	Q	94.9	Very high	93.6	Very high	0 Å²	0	7.3 Å²	7.3	0%	0	4%	0.039	C	C	.	.	H	α-helix	trans	-62.5	-39.9	177.5	-69.2	170.1	26.4	0	0	112.6	E136 P137 T138 I143 A144 L332 S335 N373 T377	E136-Q140 VanDerWaalsContact O-CG 3.25Å; E136-Q140 WeakPolarHBondContact O-CG 3.33Å; E136-Q140 PolarHBondContact O-N 3Å; P137-Q140 PolarHBondContact O-N 3.45Å; T138-Q140 PolarHBondContact O-N 3.46Å; Q140-I143 PolarHBondContact O-N 3.44Å; Q140-A144 WeakPolarHBondContact O-CB 3.31Å; Q140-A144 PolarHBondContact O-N 3.49Å; Q140-L332 HydrophobicContact CB-CD1 3.63Å; Q140-L332 HydrophobicContact CG-CD1 3.89Å; Q140-S335 WeakPolarHBondContact CG-OG 3.41Å; Q140-S335 PolarHBondContact NE2-OG 3.31Å; Q140-N373 VanDerWaalsContact CD-ND2 3.32Å; Q140-N373 PolarHBondContact NE2-ND2 3.24Å; Q140-N373 PolarHBondContact NE2-OD1 2.88Å; Q140-N373 PolarHBondContact OE1-ND2 3.4Å; Q140-N373 PolarHBondContact OE1-OD1 2.94Å; Q140-T377 HydrophobicContact CB-CG2 3.58Å; Q140-T377 PolarHBondContact OE1-OG1 2.76Å
141	A	96.4	Very high	93.6	Very high	0 Å²	0	10.8 Å²	10.8	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-62.8	-46.1	175.9	0	0	0	0	0	111.3	P137 T138 S139 I143 A144 I145 T377 L381 L389	P137-A141 WeakPolarHBondContact O-CB 3.38Å; P137-A141 PolarHBondContact O-N 2.77Å; T138-A141 PolarHBondContact O-N 2.73Å; S139-A141 VanDerWaalsContact C-N 3.35Å; S139-A141 PolarHBondContact O-N 3.45Å; A141-I143 VanDerWaalsContact C-N 3.35Å; A141-I143 PolarHBondContact O-N 2.91Å; A141-A144 PolarHBondContact O-N 3.04Å; A141-I145 VanDerWaalsContact O-CD1 3.32Å; A141-I145 WeakPolarHBondContact O-CD1 3.29Å; A141-I145 WeakPolarHBondContact O-CG1 3.46Å; A141-I145 PolarHBondContact O-N 3.32Å; A141-T377 HydrophobicContact CB-CG2 4.18Å; A141-L381 HydrophobicContact CB-CD2 4.06Å; A141-L389 HydrophobicContact CB-CD1 4.21Å
142	I	94.9	Very high	93.6	Very high	0 Å²	0	11.8 Å²	11.8	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-58.6	-47.1	176.6	-64.5	157.8	0	0	0	110.6	T138 S139 A144 I145 T146 F245 V386 L389 I390	T138-I142 HydrophobicContact CG2-CD1 4.07Å; T138-I142 WeakPolarHBondContact O-CD1 3.46Å; T138-I142 VanDerWaalsContact O-CG1 3.27Å; T138-I142 WeakPolarHBondContact O-CG1 3.28Å; T138-I142 PolarHBondContact O-N 3.05Å; S139-I142 PolarHBondContact O-N 3.05Å; I142-A144 VanDerWaalsContact C-N 3.35Å; I142-A144 PolarHBondContact O-N 3.49Å; I142-I145 PolarHBondContact O-N 3.38Å; I142-T146 WeakPolarHBondContact O-CB 3.24Å; I142-T146 PolarHBondContact O-N 3.11Å; I142-T146 PolarHBondContact O-OG1 3.02Å; I142-F245 HydrophobicContact CB-CZ 3.99Å; I142-F245 HydrophobicContact CD1-CD2 4.44Å; I142-F245 HydrophobicContact CD1-CE2 3.72Å; I142-F245 HydrophobicContact CD1-CZ 3.85Å; I142-F245 HydrophobicContact CG2-CE1 3.67Å; I142-F245 HydrophobicContact CG2-CE2 4.44Å; I142-F245 HydrophobicContact CG2-CZ 3.47Å; I142-F245 VanDerWaalsContact CG2-CZ 3.47Å; I142-V386 HydrophobicContact CB-CG1 4.41Å; I142-V386 HydrophobicContact CG1-CG1 4.2Å; I142-V386 HydrophobicContact CG2-CG1 3.83Å; I142-L389 HydrophobicContact CD1-CB 3.88Å; I142-L389 HydrophobicContact CG1-CB 3.6Å; I142-L389 HydrophobicContact CG1-CD1 4.17Å; I142-I390 HydrophobicContact CD1-CB 4.49Å; I142-I390 HydrophobicContact CD1-CG1 3.73Å; I142-I390 HydrophobicContact CG1-CG1 4.33Å; I142-I390 HydrophobicContact CG2-CG1 4.42Å
143	I	93.8	Very high	93.5	Very high	14 Å²	14	12.5 Å²	12.5	7%	0.072	7%	0.065	C	C	.	.	H	α-helix	trans	-61.3	-43.8	178.5	-61	159.9	0	0	0	110.9	S61 S139 Q140 A141 T146 F147 C328 L332	S61-I143 VanDerWaalsContact OG-CG1 3.26Å; S61-I143 WeakPolarHBondContact OG-CG1 3.07Å; S139-I143 WeakPolarHBondContact O-CD1 3.37Å; S139-I143 VanDerWaalsContact O-CG1 3.25Å; S139-I143 WeakPolarHBondContact O-CG1 3.41Å; S139-I143 PolarHBondContact O-N 3.39Å; Q140-I143 PolarHBondContact O-N 3.44Å; A141-I143 VanDerWaalsContact C-N 3.35Å; A141-I143 PolarHBondContact O-N 2.91Å; I143-T146 WeakPolarHBondContact O-CB 3.43Å; I143-T146 PolarHBondContact O-N 3.48Å; I143-F147 PolarHBondContact O-N 2.9Å; I143-C328 HydrophobicContact CG2-CB 3.93Å; I143-C328 WeakPolarHBondContact CG2-O 3.33Å; I143-L332 HydrophobicContact CG2-CB 3.82Å
144	A	95.8	Very high	93.2	Very high	0 Å²	0	13.8 Å²	13.8	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-67	-39	-179.8	0	0	0	0	0	113	Q140 A141 I142 F147 A148 A170 I174 L332	Q140-A144 WeakPolarHBondContact O-CB 3.31Å; Q140-A144 PolarHBondContact O-N 3.49Å; A141-A144 PolarHBondContact O-N 3.04Å; I142-A144 VanDerWaalsContact C-N 3.35Å; I142-A144 PolarHBondContact O-N 3.49Å; A144-F147 WeakPolarHBondContact O-CB 3.35Å; A144-F147 PolarHBondContact O-N 3.34Å; A144-A148 PolarHBondContact O-N 3.47Å; A144-A170 HydrophobicContact CB-CB 3.98Å; A144-A170 WeakPolarHBondContact O-CB 3.37Å; A144-I174 HydrophobicContact CB-CD1 3.45Å; A144-I174 VanDerWaalsContact CB-CD1 3.45Å; A144-I174 HydrophobicContact CB-CG1 3.63Å; A144-L332 HydrophobicContact CB-CD2 3.94Å
145	I	95.3	Very high	93	Very high	4 Å²	4	18.1 Å²	18.1	2%	0.021	11%	0.105	C	C	.	.	H	α-helix	trans	-66.4	-42.1	175	-63.5	156.6	0	0	0	110	A141 I142 F147 A148 N149 A170 L381 V386 L389	A141-I145 VanDerWaalsContact O-CD1 3.32Å; A141-I145 WeakPolarHBondContact O-CD1 3.29Å; A141-I145 WeakPolarHBondContact O-CG1 3.46Å; A141-I145 PolarHBondContact O-N 3.32Å; I142-I145 PolarHBondContact O-N 3.38Å; I145-F147 PolarHBondContact O-N 2.89Å; I145-A148 PolarHBondContact O-N 3Å; I145-N149 PolarHBondContact O-N 3.27Å; I145-A170 HydrophobicContact CG1-CB 4.44Å; I145-L381 HydrophobicContact CD1-CD2 4.04Å; I145-L381 HydrophobicContact CG1-CD2 3.79Å; I145-V386 HydrophobicContact CB-CG2 4.2Å; I145-V386 HydrophobicContact CD1-CG2 4.03Å; I145-V386 HydrophobicContact CG2-CG2 3.51Å; I145-L389 HydrophobicContact CD1-CD1 3.75Å
146	T	93.3	Very high	92.9	Very high	3 Å²	3	20.9 Å²	20.9	2%	0.018	12%	0.117	C	C	.	.	H	α-helix	trans	-59.1	-47.7	175	-48.7	0	0	0	0	110.8	F64 V65 I142 I143 A148 N149 Y150	F64-T146 HydrophobicContact CB-CG2 4.39Å; V65-T146 HydrophobicContact CG2-CG2 3.58Å; V65-T146 WeakPolarHBondContact CG2-OG1 3.45Å; I142-T146 WeakPolarHBondContact O-CB 3.24Å; I142-T146 PolarHBondContact O-N 3.11Å; I142-T146 PolarHBondContact O-OG1 3.02Å; I143-T146 WeakPolarHBondContact O-CB 3.43Å; I143-T146 PolarHBondContact O-N 3.48Å; T146-A148 VanDerWaalsContact C-N 3.3Å; T146-A148 PolarHBondContact O-N 3.35Å; T146-N149 PolarHBondContact O-N 3.3Å; T146-Y150 HydrophobicContact CG2-CD2 3.75Å; T146-Y150 HydrophobicContact CG2-CE2 3.86Å; T146-Y150 WeakPolarHBondContact O-CB 3.33Å; T146-Y150 VanDerWaalsContact O-CD2 3.27Å; T146-Y150 WeakPolarHBondContact O-CD2 3.39Å; T146-Y150 PolarHBondContact O-N 2.69Å
147	F	93.9	Very high	92.2	Very high	22 Å²	22	23.9 Å²	23.9	10%	0.096	14%	0.139	C	C	.	.	H	α-helix	trans	-52.2	-49.3	174.1	167.1	-94.4	0	0	0	111.8	I143 A144 I145 Y150 I151 L169 C173 A325 C328 F329	I143-F147 PolarHBondContact O-N 2.9Å; A144-F147 WeakPolarHBondContact O-CB 3.35Å; A144-F147 PolarHBondContact O-N 3.34Å; I145-F147 PolarHBondContact O-N 2.89Å; F147-Y150 PolarHBondContact O-N 3.49Å; F147-I151 HydrophobicContact CD1-CD1 4.42Å; F147-I151 HydrophobicContact CD2-CD1 4.1Å; F147-I151 HydrophobicContact CE1-CD1 3.75Å; F147-I151 HydrophobicContact CE2-CD1 3.38Å; F147-I151 HydrophobicContact CE2-CG1 4.29Å; F147-I151 HydrophobicContact CZ-CD1 3.18Å; F147-I151 HydrophobicContact CZ-CG1 4.35Å; F147-I151 PolarHBondContact O-N 3.38Å; F147-I151 VanDerWaalsContact O-N 3.1Å; F147-L169 HydrophobicContact CE1-CG 4.32Å; F147-C173 HydrophobicContact CD1-CB 3.72Å; F147-C173 HydrophobicContact CE1-CB 3.58Å; F147-C173 VanDerWaalsContact CE1-SG 3.57Å; F147-C173 HydrophobicContact CZ-CB 4.34Å; F147-A325 HydrophobicContact CD2-CB 3.99Å; F147-A325 WeakPolarHBondContact CD2-O 3.48Å; F147-A325 HydrophobicContact CE2-CB 4.12Å; F147-C328 HydrophobicContact CB-CB 3.69Å; F147-C328 HydrophobicContact CD2-CB 4.45Å; F147-F329 HydrophobicContact CD2-CB 4.31Å; F147-F329 HydrophobicContact CE2-CB 4.22Å; F147-F329 HydrophobicContact CE2-CD2 4.04Å; F147-F329 HydrophobicContact CZ-CD2 4.37Å
148	A	95.1	Very high	91.6	Very high	0 Å²	0	29.6 Å²	29.6	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-65.2	-47.3	-177	0	0	0	0	0	112.2	A144 I145 T146 Y150 I151 I152 C166 L169 A170	A144-A148 PolarHBondContact O-N 3.47Å; I145-A148 PolarHBondContact O-N 3Å; T146-A148 VanDerWaalsContact C-N 3.3Å; T146-A148 PolarHBondContact O-N 3.35Å; A148-Y150 VanDerWaalsContact C-N 3.3Å; A148-Y150 PolarHBondContact O-N 2.94Å; A148-I151 PolarHBondContact O-N 3.07Å; A148-I152 WeakPolarHBondContact O-CB 3.25Å; A148-I152 VanDerWaalsContact O-CG2 3.22Å; A148-I152 WeakPolarHBondContact O-CG2 3.38Å; A148-I152 PolarHBondContact O-N 2.92Å; A148-C166 HydrophobicContact CB-CB 4.4Å; A148-C166 WeakPolarHBondContact CB-O 3.36Å; A148-L169 HydrophobicContact CB-CB 3.99Å; A148-L169 HydrophobicContact CB-CD2 4.09Å; A148-L169 HydrophobicContact CB-CG 4.1Å; A148-A170 HydrophobicContact CB-CB 4.04Å
149	N	92.3	Very high	91.2	Very high	20 Å²	20	33.1 Å²	33.1	11%	0.107	20%	0.203	C	C	.	.	H	α-helix	trans	-58	-44	178.2	-74.7	-5.7	0	0	0	111.1	I145 T146 I151 I152 Q153 C166	I145-N149 PolarHBondContact O-N 3.27Å; T146-N149 PolarHBondContact O-N 3.3Å; N149-I151 PolarHBondContact O-N 2.87Å; N149-I152 PolarHBondContact O-N 3.46Å; N149-Q153 VanDerWaalsContact O-CB 3.23Å; N149-Q153 WeakPolarHBondContact O-CB 3.44Å; N149-Q153 PolarHBondContact O-N 3.25Å; N149-C166 PolarHBondContact OD1-SG 3.4Å; N149-C166 VanDerWaalsContact OD1-SG 3.37Å
150	Y	91.9	Very high	90.7	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-70.2	-32.5	-179.2	-88.5	-96.4	0	0	0	114.1	F64 T146 F147 A148 P154 A303 V304 A305 V306 P321 V324	F64-Y150 HydrophobicContact CB-CE2 3.88Å; F64-Y150 WeakPolarHBondContact CB-OH 3.48Å; F64-Y150 PolarHBondContact O-OH 3.01Å; F64-Y150 VanDerWaalsContact O-OH 3.13Å; T146-Y150 HydrophobicContact CG2-CD2 3.75Å; T146-Y150 HydrophobicContact CG2-CE2 3.86Å; T146-Y150 WeakPolarHBondContact O-CB 3.33Å; T146-Y150 VanDerWaalsContact O-CD2 3.27Å; T146-Y150 WeakPolarHBondContact O-CD2 3.39Å; T146-Y150 PolarHBondContact O-N 2.69Å; F147-Y150 PolarHBondContact O-N 3.49Å; A148-Y150 VanDerWaalsContact C-N 3.3Å; A148-Y150 PolarHBondContact O-N 2.94Å; Y150-P154 WeakPolarHBondContact O-CD 3.37Å; Y150-A303 HydrophobicContact CD1-CB 4.18Å; Y150-A303 HydrophobicContact CD2-CB 3.98Å; Y150-A303 HydrophobicContact CE1-CB 4.01Å; Y150-A303 HydrophobicContact CE2-CB 3.79Å; Y150-A303 HydrophobicContact CG-CB 4.19Å; Y150-V304 PolarHBondContact OH-N 2.92Å; Y150-A305 HydrophobicContact CE1-CB 3.9Å; Y150-A305 PolarHBondContact OH-N 2.81Å; Y150-V306 HydrophobicContact CD1-CG2 3.59Å; Y150-V306 HydrophobicContact CE1-CG2 3.74Å; Y150-P321 WeakPolarHBondContact O-CB 3.34Å; Y150-V324 HydrophobicContact CD1-CB 3.52Å; Y150-V324 HydrophobicContact CD1-CG1 3.38Å; Y150-V324 HydrophobicContact CD1-CG2 3.99Å; Y150-V324 HydrophobicContact CD2-CG1 3.95Å; Y150-V324 HydrophobicContact CE1-CB 3.86Å; Y150-V324 HydrophobicContact CE1-CG1 3.58Å; Y150-V324 HydrophobicContact CE1-CG2 3.86Å; Y150-V324 HydrophobicContact CE2-CG1 4.13Å; Y150-V324 HydrophobicContact CG-CB 4.08Å; Y150-V324 HydrophobicContact CG-CG1 3.56Å
151	I	92.4	Very high	90.4	Very high	73 Å²	73	38.1 Å²	38.1	37%	0.374	23%	0.229	S	C	.	.	H	α-helix	trans	-73.6	-39.4	174.9	-74.4	-168.5	0	0	0	111.8	F147 A148 N149 P154 L169 A325	F147-I151 HydrophobicContact CD1-CD1 4.42Å; F147-I151 HydrophobicContact CD2-CD1 4.1Å; F147-I151 HydrophobicContact CE1-CD1 3.75Å; F147-I151 HydrophobicContact CE2-CD1 3.38Å; F147-I151 HydrophobicContact CE2-CG1 4.29Å; F147-I151 HydrophobicContact CZ-CD1 3.18Å; F147-I151 HydrophobicContact CZ-CG1 4.35Å; F147-I151 PolarHBondContact O-N 3.38Å; F147-I151 VanDerWaalsContact O-N 3.1Å; A148-I151 PolarHBondContact O-N 3.07Å; N149-I151 PolarHBondContact O-N 2.87Å; I151-P154 WeakPolarHBondContact O-CD 3.36Å; I151-L169 HydrophobicContact CB-CD2 4.12Å; I151-L169 HydrophobicContact CG2-CD2 3.88Å; I151-A325 HydrophobicContact CD1-CB 3.9Å; I151-A325 HydrophobicContact CG1-CB 3.45Å; I151-A325 VanDerWaalsContact CG1-CB 3.45Å
152	I	92.3	Very high	90.2	Very high	21 Å²	21	41.3 Å²	41.3	11%	0.108	25%	0.249	C	C	.	.	H	α-helix	trans	-85.5	-31.1	-171.3	-157.5	167.6	0	0	0	112.3	A148 N149 P154 S155 F156 P161 A165	A148-I152 WeakPolarHBondContact O-CB 3.25Å; A148-I152 VanDerWaalsContact O-CG2 3.22Å; A148-I152 WeakPolarHBondContact O-CG2 3.38Å; A148-I152 PolarHBondContact O-N 2.92Å; N149-I152 PolarHBondContact O-N 3.46Å; I152-P154 VanDerWaalsContact C-CD 3.44Å; I152-S155 WeakPolarHBondContact O-CB 3.42Å; I152-S155 PolarHBondContact O-N 3.3Å; I152-F156 HydrophobicContact CD1-CE2 4.07Å; I152-F156 HydrophobicContact CG1-CD2 3.9Å; I152-F156 HydrophobicContact CG1-CE2 3.69Å; I152-P161 HydrophobicContact CB-CB 4.44Å; I152-P161 HydrophobicContact CD1-CB 4.2Å; I152-P161 HydrophobicContact CG1-CB 4.14Å; I152-P161 HydrophobicContact CG2-CB 3.5Å; I152-P161 HydrophobicContact CG2-CG 3.72Å; I152-A165 HydrophobicContact CD1-CB 3.61Å
153	Q	89.1	Confident	90	Very high	20 Å²	20	46.2 Å²	46.2	9%	0.093	27%	0.268	C	S	.	.	G	3₁₀ helix	trans	-51	-43.6	-176.5	-170.6	67.2	38.4	0	0	113.8	N149 S155 F156 A303 V306	N149-Q153 VanDerWaalsContact O-CB 3.23Å; N149-Q153 WeakPolarHBondContact O-CB 3.44Å; N149-Q153 PolarHBondContact O-N 3.25Å; Q153-S155 PolarHBondContact O-N 3.44Å; Q153-S155 VanDerWaalsContact O-N 3.11Å; Q153-F156 PolarHBondContact NE2-O 3.27Å; Q153-F156 CarbonylContact O-C 3.4Å; Q153-F156 WeakPolarHBondContact O-CA 3.42Å; Q153-F156 PolarHBondContact O-N 2.88Å; Q153-A303 HydrophobicContact CB-CB 4.16Å; Q153-A303 HydrophobicContact CG-CB 4.13Å; Q153-V306 HydrophobicContact CG-CB 4.46Å; Q153-V306 HydrophobicContact CG-CG1 4.15Å
154	P	87.6	Confident	89.9	Confident	59 Å²	59	51.1 Å²	51.1	38%	0.383	29%	0.294	S	S	.	.	G	3₁₀ helix	trans	-62.1	-21.9	179.4	-24.4	36.3	0	0	0	114.3	Y150 I151 I152 F156 P321	Y150-P154 WeakPolarHBondContact O-CD 3.37Å; I151-P154 WeakPolarHBondContact O-CD 3.36Å; I152-P154 VanDerWaalsContact C-CD 3.44Å; P154-F156 VanDerWaalsContact C-N 3.33Å; P154-P321 HydrophobicContact CG-CB 3.74Å; P154-P321 HydrophobicContact CG-CG 3.66Å
155	S	89.1	Confident	89.8	Confident	92 Å²	92	52.9 Å²	52.9	64%	0.643	31%	0.309	S	S	*	.	G	3₁₀ helix	trans	-81.6	-15.5	175.2	-56.2	0	0	0	0	112.7	I152 Q153 P157	I152-S155 WeakPolarHBondContact O-CB 3.42Å; I152-S155 PolarHBondContact O-N 3.3Å; Q153-S155 PolarHBondContact O-N 3.44Å; Q153-S155 VanDerWaalsContact O-N 3.11Å; S155-P157 VanDerWaalsContact C-CD 3.42Å
156	F	88.1	Confident	89.7	Confident	63 Å²	63	53 Å²	53	28%	0.276	31%	0.31	S	S	.	.			trans	-126.6	64.7	179	-61.5	-91.3	0	0	0	109.8	I152 Q153 P154 S158 C159 P161 P162	I152-F156 HydrophobicContact CD1-CE2 4.07Å; I152-F156 HydrophobicContact CG1-CD2 3.9Å; I152-F156 HydrophobicContact CG1-CE2 3.69Å; Q153-F156 PolarHBondContact NE2-O 3.27Å; Q153-F156 CarbonylContact O-C 3.4Å; Q153-F156 WeakPolarHBondContact O-CA 3.42Å; Q153-F156 PolarHBondContact O-N 2.88Å; P154-F156 VanDerWaalsContact C-N 3.33Å; F156-S158 VanDerWaalsContact C-N 3.25Å; F156-S158 PolarHBondContact O-N 2.98Å; F156-C159 WeakPolarHBondContact CB-O 3.47Å; F156-P161 HydrophobicContact CB-CB 4.46Å; F156-P161 HydrophobicContact CD2-CB 3.9Å; F156-P161 HydrophobicContact CE2-CB 4.43Å; F156-P161 HydrophobicContact CG-CB 4.23Å; F156-P162 HydrophobicContact CE1-CG 4.29Å; F156-P162 HydrophobicContact CZ-CG 4.22Å
157	P	78.9	Confident	89.8	Confident	93 Å²	93	53.8 Å²	53.8	60%	0.604	31%	0.312	S	S	*	.	T	Hydrogen-bonded Turn	trans	-70.1	-19.3	-173.2	27.6	-35.5	0	0	0	114	S155	S155-P157 VanDerWaalsContact C-CD 3.42Å
158	S	80.9	Confident	89.9	Confident	120 Å²	120	57.9 Å²	57.9	84%	0.839	34%	0.335	S	S	*	.	T	Hydrogen-bonded Turn	trans	-117.5	1.4	-174.2	-49.1	0	0	0	0	114	F156	F156-S158 VanDerWaalsContact C-N 3.25Å; F156-S158 PolarHBondContact O-N 2.98Å
159	C	85.1	Confident	89.9	Confident	73 Å²	73	60.5 Å²	60.5	49%	0.493	35%	0.349	S	S	.	.	S	Bend	trans	-152	163.5	-178.7	55.5	0	0	0	0	110.8	F156	F156-C159 WeakPolarHBondContact CB-O 3.47Å
160	D	83.4	Confident	90.2	Very high	112 Å²	112	59.6 Å²	59.6	60%	0.599	34%	0.344	S	S	*	.	P	Polyproline II helix	trans	-73.4	136.4	177.5	-58.6	-39.7	0	0	0	110.6
161	P	88	Confident	90.4	Very high	12 Å²	12	60.6 Å²	60.6	8%	0.078	35%	0.352	C	S	.	.	P	Polyproline II helix	trans	-64	146.4	177.2	27	-33.9	0	0	0	110.7	I152 F156 Y163	I152-P161 HydrophobicContact CB-CB 4.44Å; I152-P161 HydrophobicContact CD1-CB 4.2Å; I152-P161 HydrophobicContact CG1-CB 4.14Å; I152-P161 HydrophobicContact CG2-CB 3.5Å; I152-P161 HydrophobicContact CG2-CG 3.72Å; F156-P161 HydrophobicContact CB-CB 4.46Å; F156-P161 HydrophobicContact CD2-CB 3.9Å; F156-P161 HydrophobicContact CE2-CB 4.43Å; F156-P161 HydrophobicContact CG-CB 4.23Å; P161-Y163 PolarHBondContact O-N 3.11Å
162	P	91.9	Very high	90.7	Very high	66 Å²	66	59.8 Å²	59.8	43%	0.429	36%	0.356	S	S	.	.	P	Polyproline II helix	trans	-59.4	126.1	179.7	-23.3	32.6	0	0	0	111.9	F156 L164 A165 C166	F156-P162 HydrophobicContact CE1-CG 4.29Å; F156-P162 HydrophobicContact CZ-CG 4.22Å; P162-L164 VanDerWaalsContact C-N 3.27Å; P162-L164 PolarHBondContact O-N 3.2Å; P162-L164 VanDerWaalsContact O-N 3.14Å; P162-A165 HydrophobicContact CB-CB 4.23Å; P162-A165 WeakPolarHBondContact O-CB 3.49Å; P162-A165 PolarHBondContact O-N 2.93Å; P162-C166 PolarHBondContact O-N 2.86Å
163	Y	90.8	Very high	90.8	Very high	103 Å²	103	59 Å²	59	40%	0.404	35%	0.353	S	S	.	.	H	α-helix	trans	-46.7	-48.4	-178.9	173.2	-100.9	0	0	0	113.3	P161 A165 C166 R167 E384	P161-Y163 PolarHBondContact O-N 3.11Å; Y163-A165 VanDerWaalsContact C-N 3.29Å; Y163-A165 PolarHBondContact O-N 3.35Å; Y163-C166 PolarHBondContact O-N 3.45Å; Y163-R167 HydrophobicContact CD1-CG 4.26Å; Y163-R167 HydrophobicContact CD2-CG 4.25Å; Y163-R167 HydrophobicContact CE1-CG 3.81Å; Y163-R167 HydrophobicContact CE2-CG 3.8Å; Y163-R167 HydrophobicContact CG-CG 4.46Å; Y163-R167 WeakPolarHBondContact O-CG 3.32Å; Y163-R167 PolarHBondContact O-N 3.4Å; Y163-R167 PolarHBondContact OH-NE 2.92Å; Y163-E384 HydrophobicContact CE2-CB 4.32Å; Y163-E384 HydrophobicContact CE2-CG 4.41Å; Y163-E384 WeakPolarHBondContact OH-CA 3.3Å
164	L	93.1	Very high	91.2	Very high	117 Å²	117	58 Å²	58	61%	0.613	35%	0.348	S	S	*	.	H	α-helix	trans	-63.5	-35.2	-178.2	-173.3	63.7	0	0	0	112.4	P162 R167 L168	P162-L164 VanDerWaalsContact C-N 3.27Å; P162-L164 PolarHBondContact O-N 3.2Å; P162-L164 VanDerWaalsContact O-N 3.14Å; L164-R167 PolarHBondContact O-N 3.34Å; L164-L168 HydrophobicContact CD1-CD1 4.28Å; L164-L168 HydrophobicContact CD1-CG 4.21Å; L164-L168 HydrophobicContact CD2-CD1 4.5Å; L164-L168 HydrophobicContact CG-CD1 3.93Å; L164-L168 HydrophobicContact CG-CG 4.29Å; L164-L168 WeakPolarHBondContact O-CB 3.46Å; L164-L168 VanDerWaalsContact O-CG 3.25Å; L164-L168 WeakPolarHBondContact O-CG 3.47Å; L164-L168 PolarHBondContact O-N 3.43Å
165	A	93.6	Very high	91.6	Very high	37 Å²	37	58 Å²	58	31%	0.306	35%	0.349	S	S	.	.	H	α-helix	trans	-66.7	-43.8	177.8	0	0	0	0	0	110.9	I152 P162 Y163 R167 L169	I152-A165 HydrophobicContact CD1-CB 3.61Å; P162-A165 HydrophobicContact CB-CB 4.23Å; P162-A165 WeakPolarHBondContact O-CB 3.49Å; P162-A165 PolarHBondContact O-N 2.93Å; Y163-A165 VanDerWaalsContact C-N 3.29Å; Y163-A165 PolarHBondContact O-N 3.35Å; A165-R167 PolarHBondContact O-N 2.99Å; A165-L169 VanDerWaalsContact O-CB 3.3Å; A165-L169 WeakPolarHBondContact O-CB 3.39Å; A165-L169 PolarHBondContact O-N 2.9Å
166	C	92.6	Very high	91.8	Very high	6 Å²	6	58.1 Å²	58.1	4%	0.041	34%	0.342	C	S	.	.	H	α-helix	trans	-59.5	-46.3	174.4	-58.9	0	0	0	0	111.4	A148 N149 P162 Y163 L169 A170	A148-C166 HydrophobicContact CB-CB 4.4Å; A148-C166 WeakPolarHBondContact CB-O 3.36Å; N149-C166 PolarHBondContact OD1-SG 3.4Å; N149-C166 VanDerWaalsContact OD1-SG 3.37Å; P162-C166 PolarHBondContact O-N 2.86Å; Y163-C166 PolarHBondContact O-N 3.45Å; C166-L169 PolarHBondContact O-N 3.47Å; C166-A170 WeakPolarHBondContact O-CB 3.29Å; C166-A170 PolarHBondContact O-N 3.39Å
167	R	94.7	Very high	92	Very high	20 Å²	20	55.2 Å²	55.2	8%	0.075	33%	0.329	C	S	.	.	H	α-helix	trans	-67.6	-41.4	-178.2	-65	-62.1	174.1	151	-7.9	113.2	Y163 L164 A165 L169 A170 A171 L381 V383 E384	Y163-R167 HydrophobicContact CD1-CG 4.26Å; Y163-R167 HydrophobicContact CD2-CG 4.25Å; Y163-R167 HydrophobicContact CE1-CG 3.81Å; Y163-R167 HydrophobicContact CE2-CG 3.8Å; Y163-R167 HydrophobicContact CG-CG 4.46Å; Y163-R167 WeakPolarHBondContact O-CG 3.32Å; Y163-R167 PolarHBondContact O-N 3.4Å; Y163-R167 PolarHBondContact OH-NE 2.92Å; L164-R167 PolarHBondContact O-N 3.34Å; A165-R167 PolarHBondContact O-N 2.99Å; R167-L169 VanDerWaalsContact C-N 3.34Å; R167-A170 PolarHBondContact O-N 2.9Å; R167-A171 WeakPolarHBondContact O-CB 3.48Å; R167-A171 PolarHBondContact O-N 3.44Å; R167-L381 PolarHBondContact NH1-O 2.87Å; R167-V383 PolarHBondContact NH1-O 2.89Å; R167-V383 PolarHBondContact NH2-O 3.45Å; R167-E384 VanDerWaalsContact NH2-C 3.3Å; R167-E384 PolarHBondContact NH2-O 2.84Å
168	L	96.3	Very high	92.6	Very high	108 Å²	108	51 Å²	51	57%	0.565	30%	0.302	S	S	*	.	H	α-helix	trans	-66	-37.9	175.5	-70.9	174.3	0	0	0	111.7	L164 A171 A172	L164-L168 HydrophobicContact CD1-CD1 4.28Å; L164-L168 HydrophobicContact CD1-CG 4.21Å; L164-L168 HydrophobicContact CD2-CD1 4.5Å; L164-L168 HydrophobicContact CG-CD1 3.93Å; L164-L168 HydrophobicContact CG-CG 4.29Å; L164-L168 WeakPolarHBondContact O-CB 3.46Å; L164-L168 VanDerWaalsContact O-CG 3.25Å; L164-L168 WeakPolarHBondContact O-CG 3.47Å; L164-L168 PolarHBondContact O-N 3.43Å; L168-A171 PolarHBondContact O-N 3.21Å; L168-A172 VanDerWaalsContact O-CB 3.31Å; L168-A172 WeakPolarHBondContact O-CB 3.45Å; L168-A172 PolarHBondContact O-N 2.96Å
169	L	96.5	Very high	93.1	Very high	56 Å²	56	52.2 Å²	52.2	29%	0.293	29%	0.292	S	S	.	.	H	α-helix	trans	-67.6	-41	175.9	-175.4	61.3	0	0	0	111.9	F147 A148 I151 A165 C166 R167 A172 C173	F147-L169 HydrophobicContact CE1-CG 4.32Å; A148-L169 HydrophobicContact CB-CB 3.99Å; A148-L169 HydrophobicContact CB-CD2 4.09Å; A148-L169 HydrophobicContact CB-CG 4.1Å; I151-L169 HydrophobicContact CB-CD2 4.12Å; I151-L169 HydrophobicContact CG2-CD2 3.88Å; A165-L169 VanDerWaalsContact O-CB 3.3Å; A165-L169 WeakPolarHBondContact O-CB 3.39Å; A165-L169 PolarHBondContact O-N 2.9Å; C166-L169 PolarHBondContact O-N 3.47Å; R167-L169 VanDerWaalsContact C-N 3.34Å; L169-A172 PolarHBondContact O-N 3.34Å; L169-C173 WeakPolarHBondContact O-CB 3.36Å; L169-C173 PolarHBondContact O-N 3.22Å
170	A	96.9	Very high	93.3	Very high	0 Å²	0	50.7 Å²	50.7	0%	0	28%	0.281	C	S	.	.	H	α-helix	trans	-60.8	-47.3	173.1	0	0	0	0	0	111.3	A144 I145 A148 C166 R167 A172 C173 I174 L381	A144-A170 HydrophobicContact CB-CB 3.98Å; A144-A170 WeakPolarHBondContact O-CB 3.37Å; I145-A170 HydrophobicContact CG1-CB 4.44Å; A148-A170 HydrophobicContact CB-CB 4.04Å; C166-A170 WeakPolarHBondContact O-CB 3.29Å; C166-A170 PolarHBondContact O-N 3.39Å; R167-A170 PolarHBondContact O-N 2.9Å; A170-A172 PolarHBondContact O-N 3.39Å; A170-C173 WeakPolarHBondContact O-CB 3.46Å; A170-C173 PolarHBondContact O-N 2.98Å; A170-I174 WeakPolarHBondContact O-CG1 3.25Å; A170-I174 PolarHBondContact O-N 2.93Å; A170-L381 HydrophobicContact CB-CD1 4.37Å; A170-L381 HydrophobicContact CB-CD2 4.16Å
171	A	97.6	Very high	93.4	Very high	22 Å²	22	45.5 Å²	45.5	18%	0.182	25%	0.253	C	S	.	.	H	α-helix	trans	-60.6	-43.6	176.3	0	0	0	0	0	111.9	R167 L168 C173 I174 C175 L378 L381	R167-A171 WeakPolarHBondContact O-CB 3.48Å; R167-A171 PolarHBondContact O-N 3.44Å; L168-A171 PolarHBondContact O-N 3.21Å; A171-C173 VanDerWaalsContact C-N 3.32Å; A171-C173 PolarHBondContact O-N 2.84Å; A171-I174 PolarHBondContact O-N 3.35Å; A171-C175 WeakPolarHBondContact O-CB 3.15Å; A171-C175 PolarHBondContact O-N 2.99Å; A171-C175 PolarHBondContact O-SG 2.94Å; A171-L378 HydrophobicContact CB-CD2 3.76Å; A171-L381 HydrophobicContact CB-CD1 3.68Å
172	A	97.5	Very high	93.3	Very high	55 Å²	55	45.8 Å²	45.8	46%	0.455	26%	0.255	S	S	.	.	H	α-helix	trans	-61.2	-41	176.1	0	0	0	0	0	111.7	L168 L169 A170 L176	L168-A172 VanDerWaalsContact O-CB 3.31Å; L168-A172 WeakPolarHBondContact O-CB 3.45Å; L168-A172 PolarHBondContact O-N 2.96Å; L169-A172 PolarHBondContact O-N 3.34Å; A170-A172 PolarHBondContact O-N 3.39Å; A172-L176 WeakPolarHBondContact O-CB 3.44Å; A172-L176 PolarHBondContact O-N 2.89Å
173	C	95.6	Very high	93	Very high	5 Å²	5	43.8 Å²	43.8	3%	0.034	24%	0.244	C	C	.	.	H	α-helix	trans	-62.8	-47.1	176.5	-172	0	0	0	0	112	F147 L169 A170 A171 L176 L177	F147-C173 HydrophobicContact CD1-CB 3.72Å; F147-C173 HydrophobicContact CE1-CB 3.58Å; F147-C173 VanDerWaalsContact CE1-SG 3.57Å; F147-C173 HydrophobicContact CZ-CB 4.34Å; L169-C173 WeakPolarHBondContact O-CB 3.36Å; L169-C173 PolarHBondContact O-N 3.22Å; A170-C173 WeakPolarHBondContact O-CB 3.46Å; A170-C173 PolarHBondContact O-N 2.98Å; A171-C173 VanDerWaalsContact C-N 3.32Å; A171-C173 PolarHBondContact O-N 2.84Å; C173-L176 PolarHBondContact O-N 3.22Å; C173-L177 WeakPolarHBondContact O-CB 3.49Å; C173-L177 PolarHBondContact O-N 3.24Å
174	I	96.1	Very high	92.3	Very high	0 Å²	0	44.1 Å²	44.1	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-59.4	-53	176.2	-69.6	155.6	0	0	0	110.3	A144 A170 A171 L176 L177 T178 L332 T377 L381	A144-I174 HydrophobicContact CB-CD1 3.45Å; A144-I174 VanDerWaalsContact CB-CD1 3.45Å; A144-I174 HydrophobicContact CB-CG1 3.63Å; A170-I174 WeakPolarHBondContact O-CG1 3.25Å; A170-I174 PolarHBondContact O-N 2.93Å; A171-I174 PolarHBondContact O-N 3.35Å; I174-L176 VanDerWaalsContact C-N 3.31Å; I174-L176 PolarHBondContact O-N 3.02Å; I174-L177 PolarHBondContact O-N 3.45Å; I174-T178 WeakPolarHBondContact O-CB 3.24Å; I174-T178 PolarHBondContact O-N 2.89Å; I174-T178 PolarHBondContact O-OG1 3.27Å; I174-L332 HydrophobicContact CG1-CD1 4.48Å; I174-L332 HydrophobicContact CG1-CD2 3.92Å; I174-T377 HydrophobicContact CD1-CG2 3.5Å; I174-T377 HydrophobicContact CG1-CG2 4.08Å; I174-T377 HydrophobicContact CG2-CG2 4.28Å; I174-L381 HydrophobicContact CD1-CD1 3.86Å; I174-L381 HydrophobicContact CD1-CD2 4.17Å; I174-L381 HydrophobicContact CD1-CG 4.21Å
175	C	96.4	Very high	90.9	Very high	59 Å²	59	40.5 Å²	40.5	40%	0.399	23%	0.227	S	C	.	.	H	α-helix	trans	-59.1	-41.6	180	-71.4	0	0	0	0	112.4	A171 F179	A171-C175 WeakPolarHBondContact O-CB 3.15Å; A171-C175 PolarHBondContact O-N 2.99Å; A171-C175 PolarHBondContact O-SG 2.94Å; C175-F179 VanDerWaalsContact O-CB 3.29Å; C175-F179 WeakPolarHBondContact O-CB 3.27Å; C175-F179 PolarHBondContact O-N 2.78Å
176	L	93.7	Very high	89.6	Confident	94 Å²	94	44.9 Å²	44.9	49%	0.492	24%	0.24	S	C	.	.	H	α-helix	trans	-62.3	-48.4	177	177.1	63.9	0	0	0	111.2	A172 C173 I174 F179 V180 F329	A172-L176 WeakPolarHBondContact O-CB 3.44Å; A172-L176 PolarHBondContact O-N 2.89Å; C173-L176 PolarHBondContact O-N 3.22Å; I174-L176 VanDerWaalsContact C-N 3.31Å; I174-L176 PolarHBondContact O-N 3.02Å; L176-F179 WeakPolarHBondContact O-CB 3Å; L176-F179 PolarHBondContact O-N 2.66Å; L176-V180 HydrophobicContact CD1-CG2 4.5Å; L176-V180 WeakPolarHBondContact O-CG2 3.37Å; L176-V180 PolarHBondContact O-N 3.48Å; L176-F329 HydrophobicContact CD2-CE2 4.35Å
177	L	91.4	Very high	88.2	Confident	2 Å²	2	52.6 Å²	52.6	1%	0.01	27%	0.268	C	S	.	.	H	α-helix	trans	-67.1	-41	179.6	-80.1	176.3	0	0	0	112.1	C173 I174 F179 V180 N181 F329 L332 N333 I336	C173-L177 WeakPolarHBondContact O-CB 3.49Å; C173-L177 PolarHBondContact O-N 3.24Å; I174-L177 PolarHBondContact O-N 3.45Å; L177-F179 VanDerWaalsContact C-N 3.31Å; L177-F179 PolarHBondContact O-N 2.72Å; L177-V180 PolarHBondContact O-N 3.29Å; L177-N181 WeakPolarHBondContact O-CB 3.01Å; L177-N181 PolarHBondContact O-N 2.8Å; L177-N181 PolarHBondContact O-ND2 2.78Å; L177-F329 HydrophobicContact CD1-CD2 4.12Å; L177-F329 HydrophobicContact CD1-CE2 4.11Å; L177-F329 HydrophobicContact CD1-CG 4.33Å; L177-F329 HydrophobicContact CD1-CZ 4.33Å; L177-F329 HydrophobicContact CD2-CD1 4.07Å; L177-F329 HydrophobicContact CD2-CD2 4.5Å; L177-F329 HydrophobicContact CD2-CE1 3.39Å; L177-F329 HydrophobicContact CD2-CE2 3.88Å; L177-F329 HydrophobicContact CD2-CZ 3.28Å; L177-F329 HydrophobicContact CG-CD2 4.35Å; L177-F329 HydrophobicContact CG-CE1 4.24Å; L177-F329 HydrophobicContact CG-CE2 3.83Å; L177-F329 HydrophobicContact CG-CZ 3.78Å; L177-L332 HydrophobicContact CD1-CB 3.79Å; L177-L332 HydrophobicContact CD1-CD2 3.67Å; L177-L332 HydrophobicContact CD1-CG 3.6Å; L177-N333 HydrophobicContact CD1-CB 4.33Å; L177-N333 HydrophobicContact CD2-CB 3.96Å; L177-I336 HydrophobicContact CB-CD1 3.84Å
178	T	92.3	Very high	86.5	Confident	5 Å²	5	51.8 Å²	51.8	3%	0.031	27%	0.265	C	S	.	.	H	α-helix	trans	-58.4	-45.6	172.2	-57.1	0	0	0	0	110.5	I174 V180 N181 C182 L370 C374	I174-T178 WeakPolarHBondContact O-CB 3.24Å; I174-T178 PolarHBondContact O-N 2.89Å; I174-T178 PolarHBondContact O-OG1 3.27Å; T178-V180 PolarHBondContact O-N 3.42Å; T178-N181 PolarHBondContact O-N 2.79Å; T178-C182 WeakPolarHBondContact O-CB 3.48Å; T178-C182 PolarHBondContact O-N 3.16Å; T178-C182 PolarHBondContact O-SG 2.93Å; T178-L370 HydrophobicContact CG2-CB 4.18Å; T178-C374 HydrophobicContact CG2-CB 3.72Å; T178-C374 WeakPolarHBondContact OG1-CB 3.43Å
179	F	91.8	Very high	84.8	Confident	144 Å²	144	49.1 Å²	49.1	63%	0.632	25%	0.254	S	S	*	.	H	α-helix	trans	-59.5	-46.3	176.8	174.3	-98.7	0	0	0	112.3	C175 L176 L177 N181 C182 A183	C175-F179 VanDerWaalsContact O-CB 3.29Å; C175-F179 WeakPolarHBondContact O-CB 3.27Å; C175-F179 PolarHBondContact O-N 2.78Å; L176-F179 WeakPolarHBondContact O-CB 3Å; L176-F179 PolarHBondContact O-N 2.66Å; L177-F179 VanDerWaalsContact C-N 3.31Å; L177-F179 PolarHBondContact O-N 2.72Å; F179-N181 VanDerWaalsContact C-N 3.33Å; F179-N181 PolarHBondContact O-N 3.33Å; F179-C182 PolarHBondContact O-N 2.83Å; F179-A183 WeakPolarHBondContact O-CB 3.31Å; F179-A183 PolarHBondContact O-N 2.81Å
180	V	88.2	Confident	83.4	Confident	42 Å²	42	55 Å²	55	26%	0.255	27%	0.272	S	S	.	.	H	α-helix	trans	-60.4	-43.5	177.4	171.2	0	0	0	0	111.1	L176 L177 T178 A183 Y184	L176-V180 HydrophobicContact CD1-CG2 4.5Å; L176-V180 WeakPolarHBondContact O-CG2 3.37Å; L176-V180 PolarHBondContact O-N 3.48Å; L177-V180 PolarHBondContact O-N 3.29Å; T178-V180 PolarHBondContact O-N 3.42Å; V180-A183 PolarHBondContact O-N 3.49Å; V180-Y184 PolarHBondContact O-N 2.77Å
181	N	86.2	Confident	81.8	Confident	3 Å²	3	57.7 Å²	57.7	2%	0.016	29%	0.288	C	S	.	.	H	α-helix	trans	-68.4	-32.1	178.2	-78.2	-77	0	0	0	113.1	L177 T178 F179 N333 I336 L370	L177-N181 WeakPolarHBondContact O-CB 3.01Å; L177-N181 PolarHBondContact O-N 2.8Å; L177-N181 PolarHBondContact O-ND2 2.78Å; T178-N181 PolarHBondContact O-N 2.79Å; F179-N181 VanDerWaalsContact C-N 3.33Å; F179-N181 PolarHBondContact O-N 3.33Å; N181-N333 PolarHBondContact ND2-OD1 3.43Å; N181-I336 HydrophobicContact CB-CG2 4.41Å; N181-L370 HydrophobicContact CB-CD1 4.02Å; N181-L370 HydrophobicContact CB-CD2 4.33Å
182	C	86.7	Confident	80.2	Confident	17 Å²	17	58.3 Å²	58.3	12%	0.115	29%	0.288	C	S	.	.	H	α-helix	trans	-71.4	-33.4	170.8	-69	0	0	0	0	112.4	T178 F179 R363 T365 I367 L370	T178-C182 WeakPolarHBondContact O-CB 3.48Å; T178-C182 PolarHBondContact O-N 3.16Å; T178-C182 PolarHBondContact O-SG 2.93Å; F179-C182 PolarHBondContact O-N 2.83Å; C182-R363 WeakPolarHBondContact O-CD 3.41Å; C182-T365 PolarHBondContact O-OG1 2.92Å; C182-T365 VanDerWaalsContact O-OG1 3.11Å; C182-I367 HydrophobicContact CB-CG1 4.2Å; C182-L370 VanDerWaalsContact SG-CD1 3.6Å
183	A	84.4	Confident	78.6	Confident	24 Å²	24	60.5 Å²	60.5	20%	0.198	29%	0.292	C	S	.	.	H	α-helix	trans	-79.5	-49.9	-175.1	0	0	0	0	0	112.9	F179 V180 R363	F179-A183 WeakPolarHBondContact O-CB 3.31Å; F179-A183 PolarHBondContact O-N 2.81Å; V180-A183 PolarHBondContact O-N 3.49Å; A183-R363 WeakPolarHBondContact O-CD 3.33Å; A183-R363 PolarHBondContact O-NH1 3.14Å
184	Y	76	Confident	77.3	Confident	111 Å²	111	64.7 Å²	64.7	44%	0.435	32%	0.317	S	S	.	.			trans	-160.6	105	-178.4	-158.4	-103.1	0	0	0	113.6	V180 K186 W187	V180-Y184 PolarHBondContact O-N 2.77Å; Y184-K186 VanDerWaalsContact C-N 3.3Å; Y184-K186 HydrophobicContact CD1-CB 3.97Å; Y184-K186 HydrophobicContact CE1-CB 3.59Å; Y184-K186 HydrophobicContact CE1-CD 4.06Å; Y184-K186 HydrophobicContact CE1-CG 4.03Å; Y184-K186 PolarHBondContact O-N 3.43Å; Y184-W187 AromaticContact CD1-CD1 3.28Å; Y184-W187 HydrophobicContact CD1-CG 4.03Å; Y184-W187 AromaticContact CD1-NE1 3.73Å; Y184-W187 AromaticContact CE1-CD1 3.77Å; Y184-W187 PolarHBondContact O-N 3.04Å
185	V	64.4	Low	76.2	Confident	40 Å²	40	66.6 Å²	66.6	24%	0.242	33%	0.326	C	S	.	.	H	α-helix	trans	-58.2	-33.7	-174.6	166.3	0	0	0	0	114.2	W187 G188 F337 T365	V185-W187 PolarHBondContact O-N 3.39Å; V185-G188 PolarHBondContact O-N 3.38Å; V185-F337 HydrophobicContact CG1-CD2 4.44Å; V185-F337 HydrophobicContact CG1-CE2 3.73Å; V185-T365 HydrophobicContact CB-CG2 4.42Å; V185-T365 HydrophobicContact CG2-CG2 3.42Å; V185-T365 VanDerWaalsContact CG2-CG2 3.42Å
186	K	67.1	Low	74.9	Confident	129 Å²	129	64.8 Å²	64.8	56%	0.561	31%	0.313	S	S	*	.	H	α-helix	trans	-72	-16.1	-177.1	-55.5	-179.1	179.2	174.9	0	113.9	Y184 T189	Y184-K186 VanDerWaalsContact C-N 3.3Å; Y184-K186 HydrophobicContact CD1-CB 3.97Å; Y184-K186 HydrophobicContact CE1-CB 3.59Å; Y184-K186 HydrophobicContact CE1-CD 4.06Å; Y184-K186 HydrophobicContact CE1-CG 4.03Å; Y184-K186 PolarHBondContact O-N 3.43Å; K186-T189 PolarHBondContact O-OG1 3.4Å
187	W	63.4	Low	74	Confident	169 Å²	169	68 Å²	68	64%	0.64	32%	0.32	S	S	*	.	H	α-helix	trans	-76.9	-39.6	174.1	-77.5	29.1	0	0	0	110.4	Y184 V185 T189 R190 V191	Y184-W187 AromaticContact CD1-CD1 3.28Å; Y184-W187 HydrophobicContact CD1-CG 4.03Å; Y184-W187 AromaticContact CD1-NE1 3.73Å; Y184-W187 AromaticContact CE1-CD1 3.77Å; Y184-W187 PolarHBondContact O-N 3.04Å; V185-W187 PolarHBondContact O-N 3.39Å; W187-T189 PolarHBondContact O-N 3.26Å; W187-R190 PolarHBondContact O-N 3.31Å; W187-V191 WeakPolarHBondContact O-CB 3.09Å; W187-V191 VanDerWaalsContact O-CG2 3.22Å; W187-V191 WeakPolarHBondContact O-CG2 3.45Å; W187-V191 PolarHBondContact O-N 3.23Å
188	G	58	Low	73.2	Confident	2 Å²	2	69.7 Å²	69.7	2%	0.021	33%	0.333	C	S	.	.	H	α-helix	trans	-58.7	-44.1	177.6	0	0	0	0	0	112.8	V185 Q192 N333	V185-G188 PolarHBondContact O-N 3.38Å; G188-Q192 WeakPolarHBondContact O-CB 3.44Å; G188-Q192 PolarHBondContact O-N 3.06Å; G188-Q192 VanDerWaalsContact O-N 3.13Å; G188-N333 PolarHBondContact O-ND2 3.36Å; G188-N333 VanDerWaalsContact O-ND2 3.15Å
189	T	61.6	Low	72.5	Confident	53 Å²	53	69.9 Å²	69.9	33%	0.325	33%	0.334	S	S	.	.	H	α-helix	trans	-68	-41.3	-178.4	51.7	0	0	0	0	113.4	K186 W187 V191 Q192 D193	K186-T189 PolarHBondContact O-OG1 3.4Å; W187-T189 PolarHBondContact O-N 3.26Å; T189-V191 PolarHBondContact O-N 3.29Å; T189-Q192 PolarHBondContact O-N 2.88Å; T189-D193 PolarHBondContact O-N 3.33Å
190	R	65.7	Low	71.9	Confident	179 Å²	179	65 Å²	65	68%	0.675	32%	0.316	S	S	*	.	H	α-helix	trans	-67.4	-37	178.1	-72.1	-179	178.6	165.7	-1	113.3	W187 T194	W187-R190 PolarHBondContact O-N 3.31Å; R190-T194 PolarHBondContact O-OG1 3.04Å
191	V	63.9	Low	71.7	Confident	56 Å²	56	67.6 Å²	67.6	34%	0.339	33%	0.332	S	S	.	.	H	α-helix	trans	-67.6	-39.9	178.5	170.9	0	0	0	0	110.3	W187 T189 F195 F329	W187-V191 WeakPolarHBondContact O-CB 3.09Å; W187-V191 VanDerWaalsContact O-CG2 3.22Å; W187-V191 WeakPolarHBondContact O-CG2 3.45Å; W187-V191 PolarHBondContact O-N 3.23Å; T189-V191 PolarHBondContact O-N 3.29Å; V191-F195 HydrophobicContact CB-CE2 4.49Å; V191-F195 HydrophobicContact CG1-CD2 3.78Å; V191-F195 HydrophobicContact CG1-CE2 3.13Å; V191-F195 HydrophobicContact CG1-CZ 3.72Å; V191-F195 VanDerWaalsContact O-CD2 3.26Å; V191-F195 WeakPolarHBondContact O-CD2 3.38Å; V191-F195 WeakPolarHBondContact O-CG 3.37Å; V191-F195 PolarHBondContact O-N 3.44Å; V191-F329 HydrophobicContact CG1-CE1 4.26Å
192	Q	63	Low	71.7	Confident	35 Å²	35	67.8 Å²	67.8	16%	0.164	33%	0.334	C	S	.	.	H	α-helix	trans	-63.2	-45.4	177.2	179.1	-178.7	-25.7	0	0	113.5	G188 T189 T194 F195 T196	G188-Q192 WeakPolarHBondContact O-CB 3.44Å; G188-Q192 PolarHBondContact O-N 3.06Å; G188-Q192 VanDerWaalsContact O-N 3.13Å; T189-Q192 PolarHBondContact O-N 2.88Å; Q192-T194 VanDerWaalsContact C-N 3.28Å; Q192-T194 PolarHBondContact O-N 3.14Å; Q192-F195 PolarHBondContact O-N 2.77Å; Q192-T196 PolarHBondContact O-N 3.28Å; Q192-T196 VanDerWaalsContact O-N 3.11Å; Q192-T196 PolarHBondContact O-OG1 2.91Å
193	D	64.5	Low	71.8	Confident	102 Å²	102	67.1 Å²	67.1	55%	0.545	33%	0.329	S	S	.	.	H	α-helix	trans	-60.6	-40.8	-178.2	-75.4	-13.6	0	0	0	111.5	T189 F195 T196 Y197	T189-D193 PolarHBondContact O-N 3.33Å; D193-F195 PolarHBondContact O-N 3.16Å; D193-T196 PolarHBondContact O-N 2.72Å; D193-Y197 WeakPolarHBondContact O-CD2 3.2Å
194	T	68.9	Low	72.1	Confident	93 Å²	93	70.1 Å²	70.1	57%	0.571	34%	0.341	S	S	*	.	H	α-helix	trans	-64.8	-41.1	179.2	-53.5	0	0	0	0	111.8	R190 Q192 T196	R190-T194 PolarHBondContact O-OG1 3.04Å; Q192-T194 VanDerWaalsContact C-N 3.28Å; Q192-T194 PolarHBondContact O-N 3.14Å; T194-T196 VanDerWaalsContact C-N 3.32Å; T194-T196 PolarHBondContact O-N 3.05Å
195	F	72	Confident	72.8	Confident	40 Å²	40	66.3 Å²	66.3	18%	0.175	33%	0.332	C	S	.	.	H	α-helix	trans	-74.9	-21.3	-178.8	-61.3	-27.9	0	0	0	113.9	V191 Q192 D193 Y197 A198 K199 L326 F329	V191-F195 HydrophobicContact CB-CE2 4.49Å; V191-F195 HydrophobicContact CG1-CD2 3.78Å; V191-F195 HydrophobicContact CG1-CE2 3.13Å; V191-F195 HydrophobicContact CG1-CZ 3.72Å; V191-F195 VanDerWaalsContact O-CD2 3.26Å; V191-F195 WeakPolarHBondContact O-CD2 3.38Å; V191-F195 WeakPolarHBondContact O-CG 3.37Å; V191-F195 PolarHBondContact O-N 3.44Å; Q192-F195 PolarHBondContact O-N 2.77Å; D193-F195 PolarHBondContact O-N 3.16Å; F195-Y197 VanDerWaalsContact C-N 3.35Å; F195-Y197 PolarHBondContact O-N 2.83Å; F195-A198 PolarHBondContact O-N 3.41Å; F195-K199 PolarHBondContact O-N 3.38Å; F195-K199 VanDerWaalsContact O-N 3.13Å; F195-L326 HydrophobicContact CD1-CB 4.04Å; F195-L326 HydrophobicContact CD1-CD1 4.32Å; F195-L326 HydrophobicContact CD1-CD2 4.31Å; F195-L326 HydrophobicContact CD1-CG 4.45Å; F195-L326 HydrophobicContact CE1-CB 4.35Å; F195-L326 HydrophobicContact CE1-CD1 4.15Å; F195-L326 HydrophobicContact CE1-CD2 3.75Å; F195-L326 HydrophobicContact CE1-CG 4.3Å; F195-L326 HydrophobicContact CE2-CD2 4.22Å; F195-L326 HydrophobicContact CG-CB 4.22Å; F195-L326 HydrophobicContact CZ-CD2 3.71Å; F195-F329 HydrophobicContact CD2-CD1 4.34Å; F195-F329 AromaticContact CE2-CD1 3.81Å; F195-F329 HydrophobicContact CE2-CD1 3.81Å; F195-F329 HydrophobicContact CE2-CE1 4.36Å
196	T	70.1	Confident	74.1	Confident	21 Å²	21	64.4 Å²	64.4	13%	0.129	32%	0.321	C	S	.	.	H	α-helix	trans	-66	-37.3	176	-59.5	0	0	0	0	112.1	Q192 D193 T194 K199 V200	Q192-T196 PolarHBondContact O-N 3.28Å; Q192-T196 VanDerWaalsContact O-N 3.11Å; Q192-T196 PolarHBondContact O-OG1 2.91Å; D193-T196 PolarHBondContact O-N 2.72Å; T194-T196 VanDerWaalsContact C-N 3.32Å; T194-T196 PolarHBondContact O-N 3.05Å; T196-K199 VanDerWaalsContact O-CG 3.26Å; T196-K199 WeakPolarHBondContact O-CG 3.29Å; T196-V200 WeakPolarHBondContact O-CG2 3.39Å
197	Y	74.2	Confident	75.4	Confident	162 Å²	162	59.1 Å²	59.1	64%	0.635	30%	0.298	S	S	*	.	H	α-helix	trans	-71.5	-41.4	174.1	-64.4	-73	0	0	0	111.9	D193 F195 K199 V200 V201	D193-Y197 WeakPolarHBondContact O-CD2 3.2Å; F195-Y197 VanDerWaalsContact C-N 3.35Å; F195-Y197 PolarHBondContact O-N 2.83Å; Y197-K199 VanDerWaalsContact C-N 3.35Å; Y197-K199 PolarHBondContact O-N 2.63Å; Y197-V200 PolarHBondContact O-N 3.11Å; Y197-V201 WeakPolarHBondContact O-CG2 3.46Å; Y197-V201 PolarHBondContact O-N 3.28Å; Y197-V201 VanDerWaalsContact O-N 3.14Å
198	A	75.1	Confident	76.9	Confident	36 Å²	36	54.7 Å²	54.7	30%	0.298	29%	0.29	S	S	.	.	H	α-helix	trans	-59.8	-41.8	-178.4	0	0	0	0	0	112.7	F195 V201 A202	F195-A198 PolarHBondContact O-N 3.41Å; A198-V201 PolarHBondContact O-N 3.24Å; A198-A202 PolarHBondContact O-N 3.46Å
199	K	77.1	Confident	78.6	Confident	9 Å²	9	56.9 Å²	56.9	4%	0.039	30%	0.3	C	S	.	.	H	α-helix	trans	-69.2	-35.3	179.1	70.9	-177.5	177.5	-169.1	0	113.7	G56 I59 F195 T196 Y197 V201 A202 L203 S327	G56-K199 WeakPolarHBondContact O-CE 3.22Å; G56-K199 PolarHBondContact O-NZ 3.02Å; I59-K199 HydrophobicContact CG2-CD 4.47Å; I59-K199 VanDerWaalsContact O-CD 3.26Å; I59-K199 WeakPolarHBondContact O-CD 3.47Å; I59-K199 WeakPolarHBondContact O-CE 3.22Å; I59-K199 PolarHBondContact O-NZ 3Å; F195-K199 PolarHBondContact O-N 3.38Å; F195-K199 VanDerWaalsContact O-N 3.13Å; T196-K199 VanDerWaalsContact O-CG 3.26Å; T196-K199 WeakPolarHBondContact O-CG 3.29Å; Y197-K199 VanDerWaalsContact C-N 3.35Å; Y197-K199 PolarHBondContact O-N 2.63Å; K199-V201 VanDerWaalsContact C-N 3.32Å; K199-A202 PolarHBondContact O-N 3.19Å; K199-L203 PolarHBondContact O-N 3.11Å; K199-S327 WeakPolarHBondContact CB-OG 3.11Å; K199-S327 WeakPolarHBondContact CD-OG 3.42Å
200	V	80.2	Confident	80.1	Confident	42 Å²	42	54.4 Å²	54.4	26%	0.255	29%	0.285	S	S	.	.	H	α-helix	trans	-65.9	-41.1	176.9	173.7	0	0	0	0	109.5	T196 Y197 A202 L203 I204	T196-V200 WeakPolarHBondContact O-CG2 3.39Å; Y197-V200 PolarHBondContact O-N 3.11Å; V200-A202 PolarHBondContact O-N 3.49Å; V200-L203 PolarHBondContact O-N 3.45Å; V200-I204 HydrophobicContact CG1-CD1 3.79Å; V200-I204 HydrophobicContact CG1-CG1 4.42Å; V200-I204 VanDerWaalsContact O-CG1 3.25Å; V200-I204 WeakPolarHBondContact O-CG1 3.28Å; V200-I204 PolarHBondContact O-N 3.28Å
201	V	84	Confident	81.4	Confident	97 Å²	97	49.7 Å²	49.7	59%	0.588	27%	0.273	S	S	*	.	H	α-helix	trans	-61	-43.3	174.1	173.5	0	0	0	0	111.5	Y197 A198 K199 L203 I204 A205	Y197-V201 WeakPolarHBondContact O-CG2 3.46Å; Y197-V201 PolarHBondContact O-N 3.28Å; Y197-V201 VanDerWaalsContact O-N 3.14Å; A198-V201 PolarHBondContact O-N 3.24Å; K199-V201 VanDerWaalsContact C-N 3.32Å; V201-L203 PolarHBondContact O-N 2.9Å; V201-I204 PolarHBondContact O-N 2.83Å; V201-A205 PolarHBondContact O-N 2.89Å
202	A	84.8	Confident	82.9	Confident	7 Å²	7	49.9 Å²	49.9	6%	0.058	27%	0.274	C	S	.	.	H	α-helix	trans	-61.9	-42.9	178	0	0	0	0	0	112.7	A198 K199 V200 A205 I206 A323	A198-A202 PolarHBondContact O-N 3.46Å; K199-A202 PolarHBondContact O-N 3.19Å; V200-A202 PolarHBondContact O-N 3.49Å; A202-A205 WeakPolarHBondContact O-CB 3.44Å; A202-A205 PolarHBondContact O-N 2.94Å; A202-I206 WeakPolarHBondContact O-CG1 3.34Å; A202-I206 PolarHBondContact O-N 2.94Å; A202-I206 VanDerWaalsContact O-N 3.07Å; A202-A323 HydrophobicContact CB-CB 3.6Å
203	L	88.7	Confident	84.3	Confident	2 Å²	2	50.4 Å²	50.4	1%	0.01	28%	0.276	C	S	.	.	H	α-helix	trans	-66.5	-40.9	175.5	-74.6	172.3	0	0	0	112.4	I59 I63 F64 K199 V200 V201 A205 I206 I207 I281 T285	I59-L203 HydrophobicContact CG2-CD1 3.19Å; I63-L203 HydrophobicContact CG2-CD1 4.36Å; I63-L203 HydrophobicContact CG2-CD2 4.09Å; F64-L203 HydrophobicContact CE1-CD2 3.88Å; F64-L203 HydrophobicContact CZ-CD2 3.71Å; F64-L203 HydrophobicContact CZ-CG 4.09Å; K199-L203 PolarHBondContact O-N 3.11Å; V200-L203 PolarHBondContact O-N 3.45Å; V201-L203 PolarHBondContact O-N 2.9Å; L203-A205 VanDerWaalsContact C-N 3.27Å; L203-A205 PolarHBondContact O-N 3.46Å; L203-I206 PolarHBondContact O-N 3.34Å; L203-I207 VanDerWaalsContact O-CG1 3.3Å; L203-I207 WeakPolarHBondContact O-CG1 3.35Å; L203-I207 PolarHBondContact O-N 3.44Å; L203-I281 HydrophobicContact CB-CG2 4.48Å; L203-I281 HydrophobicContact CD1-CG2 4.09Å; L203-T285 HydrophobicContact CD2-CG2 4.03Å
204	I	90.5	Very high	85.6	Confident	88 Å²	88	48.5 Å²	48.5	45%	0.451	27%	0.266	S	S	.	.	H	α-helix	trans	-59.7	-41.7	174.3	-69.6	167.5	0	0	0	110.1	V200 V201 I206 I207 V208	V200-I204 HydrophobicContact CG1-CD1 3.79Å; V200-I204 HydrophobicContact CG1-CG1 4.42Å; V200-I204 VanDerWaalsContact O-CG1 3.25Å; V200-I204 WeakPolarHBondContact O-CG1 3.28Å; V200-I204 PolarHBondContact O-N 3.28Å; V201-I204 PolarHBondContact O-N 2.83Å; I204-I206 PolarHBondContact O-N 2.84Å; I204-I207 PolarHBondContact O-N 3.48Å; I204-V208 HydrophobicContact CG2-CG2 4.09Å; I204-V208 WeakPolarHBondContact O-CB 3.49Å; I204-V208 VanDerWaalsContact O-CG2 3.25Å; I204-V208 WeakPolarHBondContact O-CG2 3.29Å; I204-V208 PolarHBondContact O-N 2.7Å
205	A	90.9	Very high	86.8	Confident	31 Å²	31	49.6 Å²	49.6	26%	0.256	28%	0.276	S	S	.	.	H	α-helix	trans	-61.1	-44.1	176.9	0	0	0	0	0	112.1	V201 A202 L203 M209 F313	V201-A205 PolarHBondContact O-N 2.89Å; A202-A205 WeakPolarHBondContact O-CB 3.44Å; A202-A205 PolarHBondContact O-N 2.94Å; L203-A205 VanDerWaalsContact C-N 3.27Å; L203-A205 PolarHBondContact O-N 3.46Å; A205-M209 WeakPolarHBondContact O-CB 3.2Å; A205-M209 WeakPolarHBondContact O-CG 3.31Å; A205-M209 PolarHBondContact O-N 3.13Å; A205-F313 HydrophobicContact CB-CE1 4.43Å; A205-F313 HydrophobicContact CB-CZ 4.06Å
206	I	92.4	Very high	87.7	Confident	0 Å²	0	53.2 Å²	53.2	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-60.1	-48.7	175.1	-68.5	167.6	0	0	0	110.7	F64 A202 L203 I204 M209 G210 T285 A288 Y289 A305 F308 I320	F64-I206 HydrophobicContact CE1-CD1 4.33Å; A202-I206 WeakPolarHBondContact O-CG1 3.34Å; A202-I206 PolarHBondContact O-N 2.94Å; A202-I206 VanDerWaalsContact O-N 3.07Å; L203-I206 PolarHBondContact O-N 3.34Å; I204-I206 PolarHBondContact O-N 2.84Å; I206-M209 PolarHBondContact O-N 3.26Å; I206-G210 PolarHBondContact O-N 3.47Å; I206-T285 HydrophobicContact CG2-CG2 4.23Å; I206-A288 HydrophobicContact CG2-CB 4.01Å; I206-Y289 HydrophobicContact CD1-CE1 4.39Å; I206-Y289 HydrophobicContact CG2-CD1 4.28Å; I206-Y289 HydrophobicContact CG2-CE1 3.78Å; I206-A305 HydrophobicContact CD1-CB 4.07Å; I206-F308 HydrophobicContact CB-CE1 4.28Å; I206-F308 HydrophobicContact CG1-CD1 4.29Å; I206-F308 HydrophobicContact CG1-CE1 4.32Å; I206-F308 HydrophobicContact CG2-CD1 4.13Å; I206-F308 HydrophobicContact CG2-CE1 3.87Å; I206-F308 HydrophobicContact CG2-CZ 4.31Å; I206-I320 HydrophobicContact CD1-CD1 4.48Å; I206-I320 HydrophobicContact CG1-CD1 4.19Å
207	I	94.9	Very high	88.6	Confident	18 Å²	18	54.4 Å²	54.4	9%	0.092	31%	0.309	C	S	.	.	H	α-helix	trans	-61.3	-48.6	-179.5	-68.7	166.5	0	0	0	111	L203 I204 M209 G210 L211 I281 L284	L203-I207 VanDerWaalsContact O-CG1 3.3Å; L203-I207 WeakPolarHBondContact O-CG1 3.35Å; L203-I207 PolarHBondContact O-N 3.44Å; I204-I207 PolarHBondContact O-N 3.48Å; I207-M209 VanDerWaalsContact C-N 3.34Å; I207-M209 PolarHBondContact O-N 2.92Å; I207-G210 PolarHBondContact O-N 3.26Å; I207-L211 HydrophobicContact CG2-CD1 4.08Å; I207-L211 HydrophobicContact CG2-CG 4.48Å; I207-L211 WeakPolarHBondContact O-CG 3.43Å; I207-L211 PolarHBondContact O-N 3.24Å; I207-I281 HydrophobicContact CD1-CG2 4.15Å; I207-L284 HydrophobicContact CD1-CB 3.99Å; I207-L284 HydrophobicContact CG1-CB 3.98Å; I207-L284 HydrophobicContact CG2-CB 3.97Å; I207-L284 HydrophobicContact CG2-CD1 4.17Å
208	V	94.8	Very high	89.3	Confident	76 Å²	76	50.8 Å²	50.8	46%	0.461	30%	0.298	S	S	.	.	H	α-helix	trans	-60.9	-44.6	-179.9	169.8	0	0	0	0	110.6	I204 L211 V212	I204-V208 HydrophobicContact CG2-CG2 4.09Å; I204-V208 WeakPolarHBondContact O-CB 3.49Å; I204-V208 VanDerWaalsContact O-CG2 3.25Å; I204-V208 WeakPolarHBondContact O-CG2 3.29Å; I204-V208 PolarHBondContact O-N 2.7Å; V208-L211 PolarHBondContact O-N 3.1Å; V208-V212 WeakPolarHBondContact O-CG2 3.5Å; V208-V212 PolarHBondContact O-N 2.96Å
209	M	93.4	Very high	89.9	Confident	47 Å²	47	51.1 Å²	51.1	23%	0.232	30%	0.299	C	S	.	.	H	α-helix	trans	-64.8	-40.6	177.2	-75	-53.1	-60.3	0	0	112.7	A205 I206 I207 L211 V212 K213 F308 F313	A205-M209 WeakPolarHBondContact O-CB 3.2Å; A205-M209 WeakPolarHBondContact O-CG 3.31Å; A205-M209 PolarHBondContact O-N 3.13Å; I206-M209 PolarHBondContact O-N 3.26Å; I207-M209 VanDerWaalsContact C-N 3.34Å; I207-M209 PolarHBondContact O-N 2.92Å; M209-L211 VanDerWaalsContact C-N 3.34Å; M209-L211 PolarHBondContact O-N 2.96Å; M209-V212 PolarHBondContact O-N 3.14Å; M209-K213 WeakPolarHBondContact O-CG 3.43Å; M209-K213 PolarHBondContact O-N 3.41Å; M209-F308 HydrophobicContact CB-CE1 4.3Å; M209-F308 HydrophobicContact CB-CZ 4.24Å; M209-F313 HydrophobicContact CB-CE2 4.15Å; M209-F313 HydrophobicContact CB-CZ 4.08Å; M209-F313 HydrophobicContact CG-CD1 4.47Å; M209-F313 HydrophobicContact CG-CD2 4.48Å; M209-F313 HydrophobicContact CG-CE1 3.68Å; M209-F313 HydrophobicContact CG-CE2 3.71Å; M209-F313 HydrophobicContact CG-CZ 3.26Å
210	G	93.1	Very high	90.5	Very high	2 Å²	2	57.6 Å²	57.6	2%	0.021	33%	0.329	C	S	.	.	H	α-helix	trans	-60.1	-42.9	174.2	0	0	0	0	0	112.7	I206 I207 K213 L214	I206-G210 PolarHBondContact O-N 3.47Å; I207-G210 PolarHBondContact O-N 3.26Å; G210-K213 PolarHBondContact O-N 3.42Å; G210-L214 WeakPolarHBondContact O-CB 3.38Å; G210-L214 PolarHBondContact O-N 3.49Å
211	L	93.6	Very high	90.8	Very high	79 Å²	79	57.8 Å²	57.8	41%	0.414	33%	0.327	S	S	.	.	H	α-helix	trans	-64.9	-42	175.1	-70.7	173.8	0	0	0	112.1	I207 V208 M209 K213 L214 C215	I207-L211 HydrophobicContact CG2-CD1 4.08Å; I207-L211 HydrophobicContact CG2-CG 4.48Å; I207-L211 WeakPolarHBondContact O-CG 3.43Å; I207-L211 PolarHBondContact O-N 3.24Å; V208-L211 PolarHBondContact O-N 3.1Å; M209-L211 VanDerWaalsContact C-N 3.34Å; M209-L211 PolarHBondContact O-N 2.96Å; L211-K213 VanDerWaalsContact C-N 3.33Å; L211-K213 PolarHBondContact O-N 2.97Å; L211-L214 PolarHBondContact O-N 2.97Å; L211-C215 PolarHBondContact O-N 3.03Å; L211-C215 PolarHBondContact O-SG 2.81Å; L211-C215 VanDerWaalsContact O-SG 3.33Å
212	V	94.4	Very high	90.9	Very high	60 Å²	60	55.8 Å²	55.8	36%	0.364	31%	0.31	S	S	.	.	H	α-helix	trans	-59.7	-44.7	174.9	169	0	0	0	0	110.8	V208 M209 L214 C215 Q216	V208-V212 WeakPolarHBondContact O-CG2 3.5Å; V208-V212 PolarHBondContact O-N 2.96Å; M209-V212 PolarHBondContact O-N 3.14Å; V212-L214 PolarHBondContact O-N 3.4Å; V212-C215 PolarHBondContact O-N 2.9Å; V212-Q216 WeakPolarHBondContact O-CG 3.47Å; V212-Q216 PolarHBondContact O-N 3.44Å
213	K	92.9	Very high	91	Very high	47 Å²	47	62.3 Å²	62.3	20%	0.204	34%	0.34	C	S	.	.	H	α-helix	trans	-63.3	-39.8	177	-75.2	-72.3	-176.8	177.7	0	112.5	M209 G210 L211 Q216 G217 H218 V292	M209-K213 WeakPolarHBondContact O-CG 3.43Å; M209-K213 PolarHBondContact O-N 3.41Å; G210-K213 PolarHBondContact O-N 3.42Å; L211-K213 VanDerWaalsContact C-N 3.33Å; L211-K213 PolarHBondContact O-N 2.97Å; K213-Q216 WeakPolarHBondContact O-CB 3.19Å; K213-Q216 PolarHBondContact O-N 3.46Å; K213-G217 PolarHBondContact O-N 2.89Å; K213-H218 WeakPolarHBondContact O-CB 3.3Å; K213-H218 PolarHBondContact O-N 3.13Å; K213-H218 PolarHBondContact O-ND1 3.15Å; K213-H218 VanDerWaalsContact O-ND1 3.14Å; K213-V292 HydrophobicContact CB-CG2 4.24Å; K213-V292 HydrophobicContact CG-CG2 3.98Å
214	L	92.8	Very high	91	Very high	62 Å²	62	67.7 Å²	67.7	33%	0.325	37%	0.368	S	S	.	.	H	α-helix	trans	-63.2	-44.2	173.9	-171.4	69	0	0	0	111.4	G210 L211 V212 Q216 G217 F222 T291	G210-L214 WeakPolarHBondContact O-CB 3.38Å; G210-L214 PolarHBondContact O-N 3.49Å; L211-L214 PolarHBondContact O-N 2.97Å; V212-L214 PolarHBondContact O-N 3.4Å; L214-Q216 PolarHBondContact O-N 3.06Å; L214-G217 PolarHBondContact O-N 2.82Å; L214-F222 HydrophobicContact CD1-CD2 4.46Å; L214-F222 HydrophobicContact CD1-CE2 4.42Å; L214-T291 HydrophobicContact CB-CG2 4.03Å; L214-T291 HydrophobicContact CD1-CG2 3.95Å; L214-T291 HydrophobicContact CG-CG2 4.47Å
215	C	92.1	Very high	90.9	Very high	116 Å²	116	64.1 Å²	64.1	78%	0.784	35%	0.352	S	S	*	.	H	α-helix	trans	-64.7	-24.3	174.8	-69.5	0	0	0	0	113.5	L211 V212 G217	L211-C215 PolarHBondContact O-N 3.03Å; L211-C215 PolarHBondContact O-SG 2.81Å; L211-C215 VanDerWaalsContact O-SG 3.33Å; V212-C215 PolarHBondContact O-N 2.9Å; C215-G217 PolarHBondContact O-N 3.37Å
216	Q	92.4	Very high	91	Very high	115 Å²	115	67.9 Å²	67.9	54%	0.537	36%	0.363	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.9	-3.2	172.2	-71.3	171.5	2.6	0	0	113.3	V212 K213 L214	V212-Q216 WeakPolarHBondContact O-CG 3.47Å; V212-Q216 PolarHBondContact O-N 3.44Å; K213-Q216 WeakPolarHBondContact O-CB 3.19Å; K213-Q216 PolarHBondContact O-N 3.46Å; L214-Q216 PolarHBondContact O-N 3.06Å
217	G	88.6	Confident	90.9	Very high	46 Å²	46	74.9 Å²	74.9	47%	0.474	40%	0.396	S	S	.	.	T	Hydrogen-bonded Turn	trans	97.7	8	177.4	0	0	0	0	0	115.4	K213 L214 C215 S219	K213-G217 PolarHBondContact O-N 2.89Å; L214-G217 PolarHBondContact O-N 2.82Å; C215-G217 PolarHBondContact O-N 3.37Å; G217-S219 PolarHBondContact O-N 3.29Å
218	H	89.1	Confident	90.6	Very high	86 Å²	86	76.9 Å²	76.9	40%	0.398	42%	0.421	S	S	.	.			trans	-79	65.1	176.4	-59	75.7	0	0	0	110.7	K213	K213-H218 WeakPolarHBondContact O-CB 3.3Å; K213-H218 PolarHBondContact O-N 3.13Å; K213-H218 PolarHBondContact O-ND1 3.15Å; K213-H218 VanDerWaalsContact O-ND1 3.14Å
219	S	87.9	Confident	90.5	Very high	44 Å²	44	74 Å²	74	31%	0.308	40%	0.404	S	S	.	.			trans	-113.1	7.6	179.4	61.2	0	0	0	0	113.6	G217 H221 F222	G217-S219 PolarHBondContact O-N 3.29Å; S219-H221 VanDerWaalsContact C-N 3.28Å; S219-H221 PolarHBondContact O-N 3Å; S219-F222 PolarHBondContact O-N 3.24Å
220	E	88.3	Confident	90.3	Very high	144 Å²	144	72.9 Å²	72.9	67%	0.673	40%	0.401	S	S	*	.	G	3₁₀ helix	trans	-54.3	-43.3	-175.3	-61.5	179.7	179.5	0	0	111.9	F222 Q223	E220-F222 PolarHBondContact O-N 3.25Å; E220-F222 VanDerWaalsContact O-N 3.08Å; E220-Q223 PolarHBondContact O-N 3.21Å; E220-Q223 VanDerWaalsContact O-N 3.11Å
221	H	86.8	Confident	90.1	Very high	47 Å²	47	81.8 Å²	81.8	22%	0.218	43%	0.434	C	S	.	.	G	3₁₀ helix	trans	-62.8	-17.6	178.9	-66.4	-176.5	0	0	0	114.1	Y77 S219 Y290 L293 N294	Y77-H221 HydrophobicContact CD2-CB 4.02Å; Y77-H221 WeakPolarHBondContact CD2-O 3.35Å; Y77-H221 HydrophobicContact CE2-CB 3.59Å; Y77-H221 AromaticContact CE2-CG 3.91Å; S219-H221 VanDerWaalsContact C-N 3.28Å; S219-H221 PolarHBondContact O-N 3Å; H221-Y290 WeakPolarHBondContact CB-O 3.42Å; H221-Y290 PolarHBondContact ND1-O 3.15Å; H221-L293 PolarHBondContact CE1-O 3.34Å; H221-L293 PolarHBondContact ND1-O 2.84Å; H221-N294 PolarHBondContact CE1-OD1 2.9Å; H221-N294 PolarHBondContact NE2-OD1 3.49Å; H221-N294 VanDerWaalsContact NE2-OD1 3.12Å
222	F	87.5	Confident	89.9	Confident	54 Å²	54	82.2 Å²	82.2	24%	0.237	44%	0.437	C	S	.	.	G	3₁₀ helix	trans	-96.5	-6.4	179.4	-59.9	-78.2	0	0	0	113.8	L81 L214 S219 E220 V287 T291	L81-F222 HydrophobicContact CD1-CE1 4.32Å; L214-F222 HydrophobicContact CD1-CD2 4.46Å; L214-F222 HydrophobicContact CD1-CE2 4.42Å; S219-F222 PolarHBondContact O-N 3.24Å; E220-F222 PolarHBondContact O-N 3.25Å; E220-F222 VanDerWaalsContact O-N 3.08Å; F222-V287 HydrophobicContact CZ-CG1 4.12Å; F222-T291 HydrophobicContact CE2-CG2 3.48Å; F222-T291 VanDerWaalsContact CE2-CG2 3.48Å; F222-T291 HydrophobicContact CZ-CG2 3.94Å
223	Q	86.8	Confident	89.5	Confident	144 Å²	144	85.9 Å²	85.9	67%	0.673	45%	0.451	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.7	-46.2	-179.9	-64.9	-176.3	4.8	0	0	111.1	E220	E220-Q223 PolarHBondContact O-N 3.21Å; E220-Q223 VanDerWaalsContact O-N 3.11Å
224	D	87	Confident	89.2	Confident	115 Å²	115	83.9 Å²	83.9	62%	0.615	44%	0.444	S	S	*	.	T	Hydrogen-bonded Turn	trans	-111.4	43.2	176.2	-64	-55.3	0	0	0	111.4	F226 E227	D224-F226 PolarHBondContact O-N 2.88Å; D224-E227 HydrophobicContact CB-CB 4.18Å; D224-E227 WeakPolarHBondContact O-CB 3.37Å; D224-E227 PolarHBondContact O-N 3.47Å
225	A	90.1	Very high	89.1	Confident	13 Å²	13	83.8 Å²	83.8	11%	0.107	44%	0.444	C	S	.	.	T	Hydrogen-bonded Turn	trans	-56.3	-23.2	-169.5	0	0	0	0	0	115	S76 Y77 G78	S76-A225 WeakPolarHBondContact CB-O 3.42Å; Y77-A225 PolarHBondContact N-O 3.12Å; G78-A225 WeakPolarHBondContact CA-O 3.11Å; G78-A225 PolarHBondContact N-O 3.43Å
226	F	93.1	Very high	89	Confident	111 Å²	111	80.5 Å²	80.5	49%	0.487	42%	0.418	S	S	.	.	T	Hydrogen-bonded Turn	trans	-103.5	0.7	-178	-66.5	-80.4	0	0	0	113.8	I82 D224 G228 S229	I82-F226 HydrophobicContact CD1-CE1 3.56Å; I82-F226 HydrophobicContact CD1-CZ 3.99Å; I82-F226 HydrophobicContact CG1-CE1 4.36Å; D224-F226 PolarHBondContact O-N 2.88Å; F226-G228 PolarHBondContact O-N 3.48Å; F226-S229 VanDerWaalsContact C-OG 3.3Å; F226-S229 WeakPolarHBondContact CA-OG 3.44Å; F226-S229 WeakPolarHBondContact O-CB 3.4Å; F226-S229 PolarHBondContact O-N 2.88Å; F226-S229 PolarHBondContact O-OG 2.87Å
227	E	90.5	Very high	88.9	Confident	147 Å²	147	75 Å²	75	69%	0.687	39%	0.393	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.7	137.9	176.9	-168.3	175.1	-171.4	0	0	110.5	S76 D224 S229	S76-E227 VanDerWaalsContact CB-O 3.31Å; S76-E227 WeakPolarHBondContact CB-O 3.44Å; D224-E227 HydrophobicContact CB-CB 4.18Å; D224-E227 WeakPolarHBondContact O-CB 3.37Å; D224-E227 PolarHBondContact O-N 3.47Å; E227-S229 PolarHBondContact O-N 3.3Å
228	G	87.6	Confident	89	Confident	60 Å²	60	73.7 Å²	73.7	62%	0.619	37%	0.374	S	S	*	.	T	Hydrogen-bonded Turn	trans	72	6.5	-179.3	0	0	0	0	0	115.8	A75 F226 S230	A75-G228 WeakPolarHBondContact CB-O 3.24Å; F226-G228 PolarHBondContact O-N 3.48Å; G228-S230 PolarHBondContact O-N 3.07Å
229	S	92.3	Very high	89.2	Confident	16 Å²	16	69.6 Å²	69.6	11%	0.112	36%	0.356	C	S	.	.			trans	-55	129.7	-177.9	-61.3	0	0	0	0	112.6	S76 F226 E227	S76-S229 WeakPolarHBondContact CB-OG 3.4Å; S76-S229 PolarHBondContact OG-OG 3.02Å; F226-S229 VanDerWaalsContact C-OG 3.3Å; F226-S229 WeakPolarHBondContact CA-OG 3.44Å; F226-S229 WeakPolarHBondContact O-CB 3.4Å; F226-S229 PolarHBondContact O-N 2.88Å; F226-S229 PolarHBondContact O-OG 2.87Å; E227-S229 PolarHBondContact O-N 3.3Å
230	S	89.5	Confident	89.5	Confident	23 Å²	23	68.4 Å²	68.4	16%	0.161	35%	0.346	C	S	.	.			trans	-76.9	121.5	169.5	177.5	0	0	0	0	110.2	H73 T74 G228 N235	H73-S230 WeakPolarHBondContact O-CB 3.36Å; H73-S230 PolarHBondContact O-OG 3.2Å; T74-S230 PolarHBondContact O-N 2.93Å; G228-S230 PolarHBondContact O-N 3.07Å; S230-N235 WeakPolarHBondContact OG-CB 3.48Å; S230-N235 PolarHBondContact OG-ND2 2.96Å
231	W	89.2	Confident	89.7	Confident	188 Å²	188	61.7 Å²	61.7	71%	0.712	31%	0.314	S	S	*	.			trans	-103.6	5.3	175.5	-63.9	93	0	0	0	112.9	M79 M233	M79-W231 HydrophobicContact SD-CZ3 4.5Å; W231-M233 PolarHBondContact O-N 2.87Å
232	D	89.4	Confident	90	Very high	89 Å²	89	59.5 Å²	59.5	48%	0.476	30%	0.304	S	S	.	.			trans	-67	127	176	177.6	66.5	0	0	0	110.1	G234 N235 L236	D232-G234 PolarHBondContact O-N 3.08Å; D232-G234 VanDerWaalsContact OD2-CA 3.26Å; D232-G234 WeakPolarHBondContact OD2-CA 3.4Å; D232-G234 PolarHBondContact OD2-N 3.39Å; D232-N235 HydrophobicContact CB-CB 4.26Å; D232-N235 PolarHBondContact O-N 3.48Å; D232-N235 PolarHBondContact OD2-N 2.86Å; D232-L236 WeakPolarHBondContact O-CB 3.33Å; D232-L236 PolarHBondContact O-N 2.76Å
233	M	86.2	Confident	90.4	Very high	137 Å²	137	56.9 Å²	56.9	68%	0.675	29%	0.293	S	S	*	.	H	α-helix	trans	-63.2	-30.3	-176.9	-65.3	-173.5	-173.7	0	0	111.8	W231 S237	W231-M233 PolarHBondContact O-N 2.87Å; M233-S237 WeakPolarHBondContact O-CB 3.47Å; M233-S237 PolarHBondContact O-N 3.27Å
234	G	86.5	Confident	90.7	Very high	5 Å²	5	50 Å²	50	5%	0.052	26%	0.261	C	S	.	.	H	α-helix	trans	-68.4	-52.5	178.3	0	0	0	0	0	112.3	D232 L236 S237 L238	D232-G234 PolarHBondContact O-N 3.08Å; D232-G234 VanDerWaalsContact OD2-CA 3.26Å; D232-G234 WeakPolarHBondContact OD2-CA 3.4Å; D232-G234 PolarHBondContact OD2-N 3.39Å; G234-L236 VanDerWaalsContact C-N 3.29Å; G234-L236 PolarHBondContact O-N 3.17Å; G234-S237 PolarHBondContact O-N 3.18Å; G234-S237 VanDerWaalsContact O-N 3.14Å; G234-S237 PolarHBondContact O-OG 3.24Å; G234-L238 PolarHBondContact O-N 3.25Å; G234-L238 VanDerWaalsContact O-N 3.16Å
235	N	89.6	Confident	91	Very high	59 Å²	59	45 Å²	45	32%	0.316	23%	0.233	S	C	.	.	H	α-helix	trans	-56.7	-44.5	173.1	-77.5	-32.6	0	0	0	111.7	H73 S230 D232 S237 L238 A239	H73-N235 HydrophobicContact CB-CB 4.24Å; H73-N235 VanDerWaalsContact CB-O 3.32Å; H73-N235 WeakPolarHBondContact CB-O 3.46Å; H73-N235 PolarHBondContact ND1-OD1 3.18Å; H73-N235 WeakPolarHBondContact O-CB 3.32Å; S230-N235 WeakPolarHBondContact OG-CB 3.48Å; S230-N235 PolarHBondContact OG-ND2 2.96Å; D232-N235 HydrophobicContact CB-CB 4.26Å; D232-N235 PolarHBondContact O-N 3.48Å; D232-N235 PolarHBondContact OD2-N 2.86Å; N235-S237 VanDerWaalsContact C-N 3.27Å; N235-S237 PolarHBondContact O-N 3.14Å; N235-L238 PolarHBondContact O-N 2.9Å; N235-A239 WeakPolarHBondContact O-CB 3.47Å; N235-A239 PolarHBondContact O-N 2.92Å
236	L	90.9	Very high	91.2	Very high	48 Å²	48	44.4 Å²	44.4	25%	0.251	23%	0.229	S	C	.	.	H	α-helix	trans	-62.2	-35.9	179	-172.7	58.4	0	0	0	112.5	M79 V83 D232 G234 L240	M79-L236 HydrophobicContact CE-CD1 3.46Å; M79-L236 VanDerWaalsContact CE-CD1 3.46Å; M79-L236 HydrophobicContact CE-CD2 3.84Å; M79-L236 HydrophobicContact CE-CG 4.29Å; V83-L236 HydrophobicContact CG2-CD1 3.3Å; D232-L236 WeakPolarHBondContact O-CB 3.33Å; D232-L236 PolarHBondContact O-N 2.76Å; G234-L236 VanDerWaalsContact C-N 3.29Å; G234-L236 PolarHBondContact O-N 3.17Å; L236-L240 WeakPolarHBondContact O-CB 3.26Å; L236-L240 PolarHBondContact O-N 3.46Å
237	S	89.7	Confident	91.1	Very high	0 Å²	0	39.1 Å²	39.1	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-66.3	-40.5	175.9	75.5	0	0	0	0	112.8	M233 G234 N235 L240 Y241 V442	M233-S237 WeakPolarHBondContact O-CB 3.47Å; M233-S237 PolarHBondContact O-N 3.27Å; G234-S237 PolarHBondContact O-N 3.18Å; G234-S237 VanDerWaalsContact O-N 3.14Å; G234-S237 PolarHBondContact O-OG 3.24Å; N235-S237 VanDerWaalsContact C-N 3.27Å; N235-S237 PolarHBondContact O-N 3.14Å; S237-L240 WeakPolarHBondContact O-CB 3.19Å; S237-L240 PolarHBondContact O-N 3.41Å; S237-Y241 PolarHBondContact O-N 3.42Å; S237-V442 VanDerWaalsContact OG-CG1 3.31Å; S237-V442 WeakPolarHBondContact OG-CG1 3.48Å
238	L	90.2	Very high	91	Very high	17 Å²	17	33 Å²	33	9%	0.089	18%	0.179	C	C	.	.	H	α-helix	trans	-71.8	-35.9	177.2	-63.7	176	0	0	0	111.9	G234 N235 L240 Y241 S242 D447	G234-L238 PolarHBondContact O-N 3.25Å; G234-L238 VanDerWaalsContact O-N 3.16Å; N235-L238 PolarHBondContact O-N 2.9Å; L238-L240 VanDerWaalsContact C-N 3.3Å; L238-L240 PolarHBondContact O-N 2.89Å; L238-Y241 WeakPolarHBondContact O-CB 3.25Å; L238-Y241 PolarHBondContact O-N 3.37Å; L238-S242 PolarHBondContact O-N 3.23Å; L238-S242 PolarHBondContact O-OG 3.4Å; L238-D447 HydrophobicContact CD2-CB 4.43Å
239	A	94.4	Very high	90.8	Very high	0 Å²	0	30.8 Å²	30.8	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-59.3	-45.1	168.9	0	0	0	0	0	110.6	V70 H73 T74 V83 N235 Y241 S242 A243	V70-A239 HydrophobicContact CG1-CB 4.39Å; H73-A239 HydrophobicContact CB-CB 3.8Å; T74-A239 HydrophobicContact CG2-CB 3.77Å; V83-A239 HydrophobicContact CG1-CB 4.08Å; V83-A239 HydrophobicContact CG2-CB 4.27Å; N235-A239 WeakPolarHBondContact O-CB 3.47Å; N235-A239 PolarHBondContact O-N 2.92Å; A239-Y241 PolarHBondContact O-N 3.17Å; A239-S242 WeakPolarHBondContact O-CB 3.49Å; A239-S242 PolarHBondContact O-N 2.93Å; A239-A243 PolarHBondContact O-N 3.08Å
240	L	93.8	Very high	90.6	Very high	20 Å²	20	30 Å²	30	11%	0.105	15%	0.151	C	C	.	.	H	α-helix	trans	-65.7	-37.5	178.8	-170.7	58.1	0	0	0	111.5	V83 I86 L236 S237 L238 S242 A243 L244 L439	V83-L240 HydrophobicContact CG1-CB 4.42Å; V83-L240 HydrophobicContact CG1-CD1 4.25Å; I86-L240 HydrophobicContact CG2-CD1 4.24Å; L236-L240 WeakPolarHBondContact O-CB 3.26Å; L236-L240 PolarHBondContact O-N 3.46Å; S237-L240 WeakPolarHBondContact O-CB 3.19Å; S237-L240 PolarHBondContact O-N 3.41Å; L238-L240 VanDerWaalsContact C-N 3.3Å; L238-L240 PolarHBondContact O-N 2.89Å; L240-S242 PolarHBondContact O-N 3.43Å; L240-A243 PolarHBondContact O-N 3.46Å; L240-L244 HydrophobicContact CD1-CD1 4.3Å; L240-L244 HydrophobicContact CD1-CG 4.08Å; L240-L244 HydrophobicContact CG-CD1 3.85Å; L240-L244 HydrophobicContact CG-CG 4.11Å; L240-L244 WeakPolarHBondContact O-CB 3.32Å; L240-L244 WeakPolarHBondContact O-CG 3.49Å; L240-L244 PolarHBondContact O-N 3.33Å; L240-L439 HydrophobicContact CD2-CD2 3.69Å; L240-L439 HydrophobicContact CG-CD2 4.05Å
241	Y	92.4	Very high	90.4	Very high	2 Å²	2	29.3 Å²	29.3	1%	0.008	15%	0.145	C	C	.	.	H	α-helix	trans	-56.8	-47.8	170.1	-86.3	16.2	0	0	0	112.2	S237 L238 A239 A243 L244 F245 N391 F395 L439 P443	S237-Y241 PolarHBondContact O-N 3.42Å; L238-Y241 WeakPolarHBondContact O-CB 3.25Å; L238-Y241 PolarHBondContact O-N 3.37Å; A239-Y241 PolarHBondContact O-N 3.17Å; Y241-A243 VanDerWaalsContact C-N 3.34Å; Y241-A243 PolarHBondContact O-N 2.94Å; Y241-L244 PolarHBondContact O-N 3.03Å; Y241-F245 PolarHBondContact O-N 3.29Å; Y241-N391 HydrophobicContact CD2-CB 4.45Å; Y241-F395 HydrophobicContact CE2-CB 4.3Å; Y241-F395 WeakPolarHBondContact OH-CA 3.14Å; Y241-L439 HydrophobicContact CD1-CD2 3.98Å; Y241-L439 HydrophobicContact CE1-CB 4.08Å; Y241-L439 HydrophobicContact CE1-CD2 3.86Å; Y241-L439 VanDerWaalsContact CE1-O 3.29Å; Y241-L439 WeakPolarHBondContact CE1-O 3.26Å; Y241-L439 VanDerWaalsContact CZ-O 3.24Å; Y241-L439 PolarHBondContact OH-O 3.45Å; Y241-P443 HydrophobicContact CE1-CG 4Å; Y241-P443 HydrophobicContact CE2-CB 4.04Å; Y241-P443 HydrophobicContact CE2-CG 3.85Å; Y241-P443 WeakPolarHBondContact OH-CG 3.42Å
242	S	93.8	Very high	90	Very high	1 Å²	1	21.8 Å²	21.8	1%	0.007	12%	0.12	C	C	.	.	H	α-helix	trans	-58.7	-45.7	177.1	-66.4	0	0	0	0	111.5	S66 L238 A239 L240	S66-S242 WeakPolarHBondContact CB-O 3.45Å; S66-S242 PolarHBondContact OG-O 3Å; L238-S242 PolarHBondContact O-N 3.23Å; L238-S242 PolarHBondContact O-OG 3.4Å; A239-S242 WeakPolarHBondContact O-CB 3.49Å; A239-S242 PolarHBondContact O-N 2.93Å; L240-S242 PolarHBondContact O-N 3.43Å
243	A	95.4	Very high	89.5	Confident	0 Å²	0	17.6 Å²	17.6	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-65.8	-44	176.5	0	0	0	0	0	112.2	V70 V83 W84 A239 L240 Y241 F245 S246 Y247	V70-A243 HydrophobicContact CG2-CB 3.98Å; V83-A243 HydrophobicContact CG1-CB 3.96Å; W84-A243 HydrophobicContact CD2-CB 4.35Å; W84-A243 HydrophobicContact CE3-CB 4.33Å; A239-A243 PolarHBondContact O-N 3.08Å; L240-A243 PolarHBondContact O-N 3.46Å; Y241-A243 VanDerWaalsContact C-N 3.34Å; Y241-A243 PolarHBondContact O-N 2.94Å; A243-F245 VanDerWaalsContact C-N 3.31Å; A243-F245 PolarHBondContact O-N 2.95Å; A243-S246 VanDerWaalsContact O-CB 3.32Å; A243-S246 WeakPolarHBondContact O-CB 3.43Å; A243-S246 PolarHBondContact O-N 3.41Å; A243-S246 VanDerWaalsContact O-N 3.07Å; A243-Y247 VanDerWaalsContact O-CD2 3.27Å; A243-Y247 WeakPolarHBondContact O-CD2 3.43Å; A243-Y247 PolarHBondContact O-N 3.34Å
244	L	93.8	Very high	89.4	Confident	0 Å²	0	11 Å²	11	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-67.6	-28.8	-177.9	-75.8	-179.7	0	0	0	113.3	F90 L240 Y241 S246 Y247 S248 W398 L439	F90-L244 HydrophobicContact CD1-CD1 3.99Å; F90-L244 HydrophobicContact CD1-CD2 3.52Å; F90-L244 HydrophobicContact CD1-CG 4.43Å; F90-L244 HydrophobicContact CE1-CD1 3.95Å; F90-L244 HydrophobicContact CE1-CD2 4.12Å; F90-L244 HydrophobicContact CG-CD2 4.48Å; L240-L244 HydrophobicContact CD1-CD1 4.3Å; L240-L244 HydrophobicContact CD1-CG 4.08Å; L240-L244 HydrophobicContact CG-CD1 3.85Å; L240-L244 HydrophobicContact CG-CG 4.11Å; L240-L244 WeakPolarHBondContact O-CB 3.32Å; L240-L244 WeakPolarHBondContact O-CG 3.49Å; L240-L244 PolarHBondContact O-N 3.33Å; Y241-L244 PolarHBondContact O-N 3.03Å; L244-S246 VanDerWaalsContact C-N 3.29Å; L244-S246 PolarHBondContact O-N 3.01Å; L244-Y247 CarbonylContact O-C 3.57Å; L244-Y247 PolarHBondContact O-N 3.37Å; L244-Y247 VanDerWaalsContact O-N 3.16Å; L244-S248 PolarHBondContact O-N 3.25Å; L244-W398 HydrophobicContact CB-CZ2 3.63Å; L244-W398 HydrophobicContact CD1-CD2 4.44Å; L244-W398 HydrophobicContact CD1-CZ2 4.14Å; L244-W398 HydrophobicContact CD2-CH2 4.28Å; L244-W398 HydrophobicContact CD2-CZ2 3.93Å; L244-W398 HydrophobicContact CG-CZ2 4.11Å; L244-L439 HydrophobicContact CD1-CD1 3.49Å; L244-L439 VanDerWaalsContact CD1-CD1 3.49Å; L244-L439 HydrophobicContact CD1-CD2 3.96Å; L244-L439 HydrophobicContact CD1-CG 4.4Å
245	F	93.1	Very high	89	Confident	9 Å²	9	13.3 Å²	13.3	4%	0.039	7%	0.074	C	C	.	.	H	α-helix	trans	-57.3	-44.8	168.5	176	-106.8	0	0	0	111.4	I142 Y241 A243 Y247 S248 I390 F393	I142-F245 HydrophobicContact CB-CZ 3.99Å; I142-F245 HydrophobicContact CD1-CD2 4.44Å; I142-F245 HydrophobicContact CD1-CE2 3.72Å; I142-F245 HydrophobicContact CD1-CZ 3.85Å; I142-F245 HydrophobicContact CG2-CE1 3.67Å; I142-F245 HydrophobicContact CG2-CE2 4.44Å; I142-F245 HydrophobicContact CG2-CZ 3.47Å; I142-F245 VanDerWaalsContact CG2-CZ 3.47Å; Y241-F245 PolarHBondContact O-N 3.29Å; A243-F245 VanDerWaalsContact C-N 3.31Å; A243-F245 PolarHBondContact O-N 2.95Å; F245-Y247 VanDerWaalsContact C-N 3.28Å; F245-Y247 PolarHBondContact O-N 3.43Å; F245-S248 WeakPolarHBondContact O-CB 3.29Å; F245-S248 PolarHBondContact O-N 2.95Å; F245-S248 VanDerWaalsContact O-N 3.16Å; F245-S248 PolarHBondContact O-OG 2.87Å; F245-I390 HydrophobicContact CB-CG2 3.89Å; F245-I390 HydrophobicContact CD1-CD1 4.14Å; F245-I390 HydrophobicContact CD1-CG1 4.12Å; F245-I390 HydrophobicContact CD2-CG1 4.44Å; F245-I390 HydrophobicContact CE1-CG1 4.4Å; F245-I390 HydrophobicContact CG-CG1 4.15Å; F245-I390 HydrophobicContact CG-CG2 4.22Å; F245-F393 AromaticContact CD2-CD1 3.6Å; F245-F393 HydrophobicContact CD2-CD1 3.6Å; F245-F393 AromaticContact CD2-CE1 3.72Å; F245-F393 HydrophobicContact CD2-CE1 3.72Å; F245-F393 HydrophobicContact CD2-CG 4.28Å; F245-F393 HydrophobicContact CD2-CZ 4.48Å; F245-F393 HydrophobicContact CE2-CD1 4.15Å; F245-F393 HydrophobicContact CE2-CE1 4.28Å; F245-F393 HydrophobicContact CE2-CG 4.44Å
246	S	93.3	Very high	88.2	Confident	1 Å²	1	11 Å²	11	1%	0.007	6%	0.062	C	C	.	.	H	α-helix	trans	-65.6	-30.2	175.8	-73.1	0	0	0	0	113.6	G62 I63 S66 W84 A243 L244 S248 Y282	G62-S246 WeakPolarHBondContact CA-OG 3.27Å; G62-S246 PolarHBondContact O-OG 2.7Å; G62-S246 VanDerWaalsContact O-OG 3.05Å; I63-S246 PolarHBondContact N-OG 2.99Å; S66-S246 WeakPolarHBondContact CB-OG 3.46Å; S66-S246 PolarHBondContact OG-OG 3.28Å; W84-S246 WeakPolarHBondContact CH2-OG 3.15Å; A243-S246 VanDerWaalsContact O-CB 3.32Å; A243-S246 WeakPolarHBondContact O-CB 3.43Å; A243-S246 PolarHBondContact O-N 3.41Å; A243-S246 VanDerWaalsContact O-N 3.07Å; L244-S246 VanDerWaalsContact C-N 3.29Å; L244-S246 PolarHBondContact O-N 3.01Å; S246-S248 VanDerWaalsContact C-N 3.35Å; S246-Y282 WeakPolarHBondContact O-CE2 3.49Å; S246-Y282 PolarHBondContact O-OH 2.84Å
247	Y	91.9	Very high	87.7	Confident	0 Å²	0	8.8 Å²	8.8	0%	0	5%	0.05	C	C	.	.	T	Hydrogen-bonded Turn	trans	-86.4	-1.8	176	-73.6	-71.5	0	0	0	113.6	M58 W84 G88 S91 A243 L244 F245 V278 Y282	M58-Y247 HydrophobicContact CE-CD1 3.88Å; M58-Y247 VanDerWaalsContact CE-O 3.28Å; M58-Y247 WeakPolarHBondContact CE-O 3.17Å; W84-Y247 HydrophobicContact CE3-CD2 4.49Å; W84-Y247 AromaticContact CE3-CE2 3.67Å; W84-Y247 HydrophobicContact CE3-CE2 3.67Å; W84-Y247 HydrophobicContact CZ3-CE2 4.06Å; W84-Y247 WeakPolarHBondContact O-CE2 3.4Å; W84-Y247 PolarHBondContact O-OH 3.47Å; G88-Y247 VanDerWaalsContact CA-CZ 3.43Å; G88-Y247 VanDerWaalsContact N-CE2 3.32Å; S91-Y247 VanDerWaalsContact OG-CB 3.29Å; S91-Y247 WeakPolarHBondContact OG-CB 3.49Å; A243-Y247 VanDerWaalsContact O-CD2 3.27Å; A243-Y247 WeakPolarHBondContact O-CD2 3.43Å; A243-Y247 PolarHBondContact O-N 3.34Å; L244-Y247 CarbonylContact O-C 3.57Å; L244-Y247 PolarHBondContact O-N 3.37Å; L244-Y247 VanDerWaalsContact O-N 3.16Å; F245-Y247 VanDerWaalsContact C-N 3.28Å; F245-Y247 PolarHBondContact O-N 3.43Å; Y247-V278 HydrophobicContact CD1-CG1 4.21Å; Y247-V278 HydrophobicContact CE1-CG1 4.19Å; Y247-Y282 AromaticContact CD1-CD2 3.87Å; Y247-Y282 HydrophobicContact CD1-CD2 3.87Å; Y247-Y282 AromaticContact CD1-CE2 3.85Å; Y247-Y282 HydrophobicContact CD1-CE2 3.85Å; Y247-Y282 HydrophobicContact CD2-CD2 4.41Å; Y247-Y282 AromaticContact CE1-CD2 3.45Å; Y247-Y282 HydrophobicContact CE1-CD2 3.45Å; Y247-Y282 VanDerWaalsContact CE1-CD2 3.45Å; Y247-Y282 AromaticContact CE1-CE2 3.92Å; Y247-Y282 HydrophobicContact CE1-CE2 3.92Å; Y247-Y282 HydrophobicContact CE1-CG 4.44Å; Y247-Y282 HydrophobicContact CE2-CD2 4.05Å; Y247-Y282 HydrophobicContact CG-CD2 4.33Å; Y247-Y282 HydrophobicContact CG-CE2 4.22Å; Y247-Y282 AromaticContact CZ-CD2 3.56Å
248	S	87.8	Confident	87.1	Confident	19 Å²	19	11.8 Å²	11.8	13%	0.133	6%	0.064	C	C	.	.	T	Hydrogen-bonded Turn	trans	-68.2	158	178.2	70.2	0	0	0	0	112	L244 F245 S246	L244-S248 PolarHBondContact O-N 3.25Å; F245-S248 WeakPolarHBondContact O-CB 3.29Å; F245-S248 PolarHBondContact O-N 2.95Å; F245-S248 VanDerWaalsContact O-N 3.16Å; F245-S248 PolarHBondContact O-OG 2.87Å; S246-S248 VanDerWaalsContact C-N 3.35Å
249	G	83.5	Confident	86.7	Confident	13 Å²	13	12.7 Å²	12.7	13%	0.134	7%	0.068	C	C	.	.	T	Hydrogen-bonded Turn	trans	100.2	-2.9	175.5	0	0	0	0	0	115.9	D251 T252	G249-D251 WeakPolarHBondContact CA-OD1 3.43Å; G249-D251 PolarHBondContact O-N 2.84Å; G249-T252 WeakPolarHBondContact O-CB 3.38Å; G249-T252 PolarHBondContact O-N 3.23Å; G249-T252 VanDerWaalsContact O-N 3.08Å; G249-T252 PolarHBondContact O-OG1 2.76Å
250	W	87.3	Confident	86.2	Confident	0 Å²	0	12.9 Å²	12.9	0%	0	7%	0.069	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63	-25.4	171.8	53.1	-106.1	0	0	0	113.1	V54 M58 A95 Y98 T252 M275 W398 V401	V54-W250 HydrophobicContact CG1-CB 4.33Å; M58-W250 HydrophobicContact CE-CB 4.36Å; M58-W250 HydrophobicContact CG-CB 4.37Å; M58-W250 HydrophobicContact SD-CB 3.83Å; A95-W250 VanDerWaalsContact CA-CE3 3.49Å; A95-W250 HydrophobicContact CB-CB 4.31Å; A95-W250 HydrophobicContact CB-CD2 3.7Å; A95-W250 HydrophobicContact CB-CE3 3.6Å; A95-W250 HydrophobicContact CB-CG 4.01Å; A95-W250 HydrophobicContact CB-CZ3 4.26Å; Y98-W250 VanDerWaalsContact CB-CZ3 3.46Å; Y98-W250 HydrophobicContact CD1-CH2 4.23Å; Y98-W250 AromaticContact CD1-CZ3 3.71Å; Y98-W250 HydrophobicContact CD1-CZ3 3.71Å; Y98-W250 AromaticContact CD2-CH2 3.55Å; Y98-W250 HydrophobicContact CD2-CH2 3.55Å; Y98-W250 AromaticContact CD2-CZ3 3.68Å; Y98-W250 HydrophobicContact CD2-CZ3 3.68Å; Y98-W250 HydrophobicContact CE1-CZ3 4.33Å; Y98-W250 AromaticContact CE2-CH2 3.88Å; Y98-W250 HydrophobicContact CE2-CH2 3.88Å; Y98-W250 HydrophobicContact CE2-CZ3 4.31Å; Y98-W250 AromaticContact CG-CH2 3.76Å; Y98-W250 HydrophobicContact CG-CH2 3.76Å; Y98-W250 AromaticContact CG-CZ3 3.35Å; Y98-W250 HydrophobicContact CG-CZ3 3.35Å; W250-T252 PolarHBondContact O-N 2.92Å; W250-M275 HydrophobicContact CB-CE 4.42Å; W250-M275 HydrophobicContact CB-SD 3.54Å; W250-M275 VanDerWaalsContact CB-SD 3.54Å; W250-M275 HydrophobicContact CG-CE 4.33Å; W250-M275 HydrophobicContact CG-SD 4.04Å; W250-W398 HydrophobicContact CZ2-CH2 4.44Å; W250-W398 HydrophobicContact CZ2-CZ3 4.15Å; W250-V401 HydrophobicContact CH2-CG1 3.93Å; W250-V401 HydrophobicContact CZ2-CG1 4.07Å
251	D	86.6	Confident	85.8	Confident	7 Å²	7	16.6 Å²	16.6	4%	0.037	8%	0.084	C	C	.	.	T	Hydrogen-bonded Turn	trans	-74.2	-7.7	175.1	59.7	-22.6	0	0	0	112.9	Y98 G249 L253 N254 F255 Y397	Y98-D251 HydrophobicContact CD1-CB 4.1Å; Y98-D251 HydrophobicContact CE1-CB 4.13Å; G249-D251 WeakPolarHBondContact CA-OD1 3.43Å; G249-D251 PolarHBondContact O-N 2.84Å; D251-L253 PolarHBondContact O-N 2.92Å; D251-N254 VanDerWaalsContact O-CB 3.25Å; D251-N254 WeakPolarHBondContact O-CB 3.25Å; D251-N254 PolarHBondContact O-N 2.84Å; D251-F255 VanDerWaalsContact O-CD2 3.32Å; D251-F255 WeakPolarHBondContact O-CD2 3.27Å; D251-Y397 PolarHBondContact OD1-OH 2.99Å; D251-Y397 PolarHBondContact OD2-OH 2.95Å
252	T	79.6	Confident	85.6	Confident	30 Å²	30	22.2 Å²	22.2	18%	0.184	11%	0.114	C	C	.	.	H	α-helix	trans	-59.5	-36	179.3	-46.8	0	0	0	0	112	L53 N57 G249 W250 N254 F255	L53-T252 HydrophobicContact CD2-CG2 4.02Å; N57-T252 WeakPolarHBondContact ND2-CB 3.43Å; N57-T252 WeakPolarHBondContact ND2-CG2 3.46Å; N57-T252 PolarHBondContact ND2-OG1 3.37Å; G249-T252 WeakPolarHBondContact O-CB 3.38Å; G249-T252 PolarHBondContact O-N 3.23Å; G249-T252 VanDerWaalsContact O-N 3.08Å; G249-T252 PolarHBondContact O-OG1 2.76Å; W250-T252 PolarHBondContact O-N 2.92Å; T252-N254 PolarHBondContact O-N 2.81Å; T252-F255 WeakPolarHBondContact O-CB 3.48Å; T252-F255 PolarHBondContact O-N 3.47Å
253	L	80.3	Confident	85.2	Confident	1 Å²	1	23.1 Å²	23.1	1%	0.005	12%	0.12	C	C	.	.	H	α-helix	trans	-63.6	-28.3	-180	-163.8	63	0	0	0	111.6	L53 V54 D251 F255 V256 T257 I260 L267 A270	L53-L253 HydrophobicContact CD2-CD1 4.37Å; V54-L253 HydrophobicContact CG2-CB 3.82Å; V54-L253 HydrophobicContact CG2-CD2 3.88Å; V54-L253 HydrophobicContact CG2-CG 4.32Å; D251-L253 PolarHBondContact O-N 2.92Å; L253-F255 VanDerWaalsContact C-N 3.32Å; L253-F255 PolarHBondContact O-N 3.31Å; L253-V256 HydrophobicContact CD1-CG2 4.12Å; L253-V256 WeakPolarHBondContact O-CG2 3.16Å; L253-V256 PolarHBondContact O-N 3.18Å; L253-T257 PolarHBondContact O-N 2.93Å; L253-I260 HydrophobicContact CD1-CD1 3.66Å; L253-I260 HydrophobicContact CD1-CG1 4.37Å; L253-I260 HydrophobicContact CD2-CD1 4.38Å; L253-I260 HydrophobicContact CG-CD1 3.67Å; L253-L267 HydrophobicContact CB-CD1 4.06Å; L253-L267 HydrophobicContact CD2-CD1 3.63Å; L253-L267 HydrophobicContact CG-CD1 3.57Å; L253-A270 HydrophobicContact CD2-CB 3.51Å
254	N	84.5	Confident	84.8	Confident	0 Å²	0	29.1 Å²	29.1	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-69.3	-26.9	175.1	-69.6	77.5	0	0	0	113.1	Y98 A110 Y114 D251 T252 V256 T257	Y98-N254 PolarHBondContact O-ND2 2.72Å; A110-N254 HydrophobicContact CB-CB 3.77Å; Y114-N254 HydrophobicContact CE2-CB 4.43Å; Y114-N254 WeakPolarHBondContact OH-CB 3.26Å; Y114-N254 PolarHBondContact OH-ND2 2.85Å; D251-N254 VanDerWaalsContact O-CB 3.25Å; D251-N254 WeakPolarHBondContact O-CB 3.25Å; D251-N254 PolarHBondContact O-N 2.84Å; T252-N254 PolarHBondContact O-N 2.81Å; N254-V256 VanDerWaalsContact C-N 3.31Å; N254-T257 VanDerWaalsContact C-OG1 3.31Å; N254-T257 VanDerWaalsContact CA-OG1 3.31Å; N254-T257 WeakPolarHBondContact CA-OG1 3.21Å; N254-T257 PolarHBondContact O-OG1 3.23Å
255	F	76.4	Confident	84.6	Confident	52 Å²	52	37.8 Å²	37.8	23%	0.228	18%	0.181	C	C	.	.	H	α-helix	trans	-70.8	-29.2	175.6	-71.7	-91.1	0	0	0	112.5	S108 G109 A110 D251 T252 L253 L342	S108-F255 WeakPolarHBondContact CB-O 3.26Å; S108-F255 PolarHBondContact OG-O 2.83Å; G109-F255 WeakPolarHBondContact O-CE1 3.31Å; A110-F255 HydrophobicContact CB-CD1 3.82Å; A110-F255 HydrophobicContact CB-CD2 3.47Å; A110-F255 VanDerWaalsContact CB-CD2 3.47Å; A110-F255 HydrophobicContact CB-CE1 3.77Å; A110-F255 HydrophobicContact CB-CE2 3.45Å; A110-F255 VanDerWaalsContact CB-CE2 3.45Å; A110-F255 HydrophobicContact CB-CG 3.69Å; A110-F255 HydrophobicContact CB-CZ 3.61Å; D251-F255 VanDerWaalsContact O-CD2 3.32Å; D251-F255 WeakPolarHBondContact O-CD2 3.27Å; T252-F255 WeakPolarHBondContact O-CB 3.48Å; T252-F255 PolarHBondContact O-N 3.47Å; L253-F255 VanDerWaalsContact C-N 3.32Å; L253-F255 PolarHBondContact O-N 3.31Å; F255-L342 HydrophobicContact CE1-CD1 4.46Å
256	V	74.6	Confident	84.4	Confident	11 Å²	11	38.5 Å²	38.5	7%	0.067	19%	0.185	C	C	.	.	T	Hydrogen-bonded Turn	trans	-105.2	20.2	-177.9	-62.3	0	0	0	0	112.8	I45 L53 L253 N254 E258 E259 I260	I45-V256 HydrophobicContact CD1-CB 3.92Å; I45-V256 HydrophobicContact CD1-CG2 3.8Å; L53-V256 HydrophobicContact CD1-CG2 4.29Å; L253-V256 HydrophobicContact CD1-CG2 4.12Å; L253-V256 WeakPolarHBondContact O-CG2 3.16Å; L253-V256 PolarHBondContact O-N 3.18Å; N254-V256 VanDerWaalsContact C-N 3.31Å; V256-E258 PolarHBondContact O-N 3.1Å; V256-E258 VanDerWaalsContact O-N 3.16Å; V256-E259 HydrophobicContact CB-CB 4.5Å; V256-E259 WeakPolarHBondContact O-CB 3.45Å; V256-E259 PolarHBondContact O-N 3.38Å; V256-I260 WeakPolarHBondContact O-CG1 3.45Å; V256-I260 PolarHBondContact O-N 2.54Å
257	T	78.5	Confident	84.2	Confident	2 Å²	2	38.4 Å²	38.4	1%	0.012	19%	0.185	C	C	.	.	G	3₁₀ helix	trans	-55.1	-36.6	-177.3	-53.3	0	0	0	0	112.8	G102 T106 L253 N254 E259 I260 P263	G102-T257 WeakPolarHBondContact O-CG2 3.33Å; T106-T257 HydrophobicContact CG2-CG2 4.42Å; L253-T257 PolarHBondContact O-N 2.93Å; N254-T257 VanDerWaalsContact C-OG1 3.31Å; N254-T257 VanDerWaalsContact CA-OG1 3.31Å; N254-T257 WeakPolarHBondContact CA-OG1 3.21Å; N254-T257 PolarHBondContact O-OG1 3.23Å; T257-E259 PolarHBondContact O-N 3.16Å; T257-I260 PolarHBondContact O-N 2.9Å; T257-P263 HydrophobicContact CG2-CB 3.97Å
258	E	77.8	Confident	84.1	Confident	63 Å²	63	39.5 Å²	39.5	29%	0.294	19%	0.192	S	C	.	.	G	3₁₀ helix	trans	-62.4	-27.9	177.4	-66.7	-178.5	-169.9	0	0	113	L41 K43 T106 K107 S108 V256	L41-E258 HydrophobicContact CD1-CB 4.33Å; K43-E258 WeakPolarHBondContact CG-O 3.27Å; T106-E258 WeakPolarHBondContact O-CG 3.36Å; K107-E258 WeakPolarHBondContact CA-OE1 3.42Å; S108-E258 PolarHBondContact N-OE1 2.79Å; V256-E258 PolarHBondContact O-N 3.1Å; V256-E258 VanDerWaalsContact O-N 3.16Å
259	E	81.9	Confident	84.3	Confident	35 Å²	35	42 Å²	42	16%	0.164	20%	0.203	C	C	.	.	G	3₁₀ helix	trans	-90	-7.8	-178.1	-58.3	177.1	-134.1	0	0	112.6	L41 K43 E44 I45 V256 T257 R341	L41-E259 HydrophobicContact CB-CG 4.11Å; L41-E259 HydrophobicContact CD1-CG 4.16Å; K43-E259 CarbonylContact C-O 3.59Å; K43-E259 VanDerWaalsContact CA-O 3.31Å; K43-E259 WeakPolarHBondContact CA-O 3.26Å; E44-E259 PolarHBondContact N-O 2.9Å; I45-E259 HydrophobicContact CD1-CB 3.7Å; I45-E259 HydrophobicContact CG1-CB 4.04Å; I45-E259 PolarHBondContact N-O 2.94Å; V256-E259 HydrophobicContact CB-CB 4.5Å; V256-E259 WeakPolarHBondContact O-CB 3.45Å; V256-E259 PolarHBondContact O-N 3.38Å; T257-E259 PolarHBondContact O-N 3.16Å; E259-R341 IonicContact OE1-CZ 2.89Å; E259-R341 IonicContact OE1-NH1 2.87Å; E259-R341 PolarHBondContact OE1-NH1 2.84Å; E259-R341 IonicContact OE1-NH2 3.38Å
260	I	84.1	Confident	84.7	Confident	4 Å²	4	41.4 Å²	41.4	2%	0.021	20%	0.197	C	C	.	.	B	Isolated β-bridge	trans	-80.9	131.9	-177.2	-62.6	172.7	0	0	0	111.3	I45 L253 V256 T257 N262 P263 N266 L267	I45-I260 HydrophobicContact CB-CG1 4.23Å; I45-I260 HydrophobicContact CG2-CG1 4.24Å; L253-I260 HydrophobicContact CD1-CD1 3.66Å; L253-I260 HydrophobicContact CD1-CG1 4.37Å; L253-I260 HydrophobicContact CD2-CD1 4.38Å; L253-I260 HydrophobicContact CG-CD1 3.67Å; V256-I260 WeakPolarHBondContact O-CG1 3.45Å; V256-I260 PolarHBondContact O-N 2.54Å; T257-I260 PolarHBondContact O-N 2.9Å; I260-N262 PolarHBondContact O-N 3.14Å; I260-P263 HydrophobicContact CB-CB 4.36Å; I260-P263 HydrophobicContact CG2-CB 4.33Å; I260-N266 HydrophobicContact CG2-CB 4Å; I260-L267 HydrophobicContact CD1-CD1 3.94Å
261	K	85.7	Confident	84.8	Confident	99 Å²	99	41.5 Å²	41.5	43%	0.43	20%	0.198	S	C	.	.	S	Bend	trans	-68.9	125.7	168.4	-66.8	-178.9	-179.6	178.1	0	109.1	K43 I45 N266	K43-K261 HydrophobicContact CB-CG 4.33Å; K43-K261 WeakPolarHBondContact O-CE 3.3Å; K43-K261 VanDerWaalsContact O-CG 3.24Å; K43-K261 WeakPolarHBondContact O-CG 3.17Å; I45-K261 PolarHBondContact O-N 2.65Å; K261-N266 WeakPolarHBondContact O-CB 3.41Å; K261-N266 PolarHBondContact O-ND2 2.93Å
262	N	86.9	Confident	85	Confident	119 Å²	119	43.1 Å²	43.1	64%	0.636	22%	0.216	S	C	*	.	S	Bend	trans	48.6	64.4	179.7	-61.4	-24.1	0	0	0	113	I260 E264 R265 N266	I260-N262 PolarHBondContact O-N 3.14Å; N262-E264 PolarHBondContact O-N 2.92Å; N262-R265 PolarHBondContact O-N 2.97Å; N262-R265 VanDerWaalsContact O-N 3.13Å; N262-N266 WeakPolarHBondContact O-CB 3.32Å; N262-N266 PolarHBondContact O-N 3.46Å
263	P	85.5	Confident	85.6	Confident	21 Å²	21	45.3 Å²	45.3	14%	0.136	23%	0.226	C	C	.	.	H	α-helix	trans	-57.9	-35.4	-172.5	23.7	-33.2	0	0	0	112.6	T257 I260 R265 L267	T257-P263 HydrophobicContact CG2-CB 3.97Å; I260-P263 HydrophobicContact CB-CB 4.36Å; I260-P263 HydrophobicContact CG2-CB 4.33Å; P263-R265 PolarHBondContact O-N 3.25Å; P263-R265 VanDerWaalsContact O-N 3.12Å; P263-L267 WeakPolarHBondContact O-CB 3.39Å; P263-L267 PolarHBondContact O-N 3.16Å
264	E	87.1	Confident	86.1	Confident	126 Å²	126	45.2 Å²	45.2	59%	0.589	23%	0.225	S	C	*	.	H	α-helix	trans	-54.2	-34.7	178.7	-58.5	-175.4	175.5	0	0	114	N262 P268 P421	N262-E264 PolarHBondContact O-N 2.92Å; E264-P268 WeakPolarHBondContact O-CD 3.37Å; E264-P268 WeakPolarHBondContact O-CG 3.47Å; E264-P421 HydrophobicContact CB-CB 3.89Å; E264-P421 HydrophobicContact CB-CG 4.5Å; E264-P421 HydrophobicContact CG-CB 3.7Å; E264-P421 HydrophobicContact CG-CG 3.76Å
265	R	89.3	Confident	86.4	Confident	181 Å²	181	45.3 Å²	45.3	68%	0.683	23%	0.226	S	C	*	.	H	α-helix	trans	-102.7	-43.2	-179.5	-179.7	178.2	174.1	-173.3	-0.4	112.1	N262 P263 P268 L269	N262-R265 PolarHBondContact O-N 2.97Å; N262-R265 VanDerWaalsContact O-N 3.13Å; P263-R265 PolarHBondContact O-N 3.25Å; P263-R265 VanDerWaalsContact O-N 3.12Å; R265-P268 WeakPolarHBondContact O-CD 3.3Å; R265-L269 HydrophobicContact CG-CD1 3.68Å; R265-L269 WeakPolarHBondContact O-CB 3.37Å; R265-L269 WeakPolarHBondContact O-CD1 3.43Å; R265-L269 WeakPolarHBondContact O-CG 3.22Å; R265-L269 PolarHBondContact O-N 3.04Å
266	N	90.3	Very high	87.2	Confident	24 Å²	24	46.2 Å²	46.2	13%	0.128	24%	0.237	C	C	.	.	H	α-helix	trans	-79.5	-31.2	-171	-74	-8.2	0	0	0	112.6	L47 I260 K261 N262 A270	L47-N266 HydrophobicContact CB-CB 4.47Å; L47-N266 HydrophobicContact CD1-CB 4.31Å; L47-N266 WeakPolarHBondContact CD1-O 3.43Å; I260-N266 HydrophobicContact CG2-CB 4Å; K261-N266 WeakPolarHBondContact O-CB 3.41Å; K261-N266 PolarHBondContact O-ND2 2.93Å; N262-N266 WeakPolarHBondContact O-CB 3.32Å; N262-N266 PolarHBondContact O-N 3.46Å; N266-A270 WeakPolarHBondContact O-CB 3.22Å; N266-A270 PolarHBondContact O-N 3.08Å
267	L	88.8	Confident	88	Confident	0 Å²	0	49.1 Å²	49.1	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-63.9	-52.2	176.7	-179.6	76.2	0	0	0	111.2	T103 L253 I260 P263 L269 A270 I271	T103-L267 HydrophobicContact CG2-CD2 4.14Å; L253-L267 HydrophobicContact CB-CD1 4.06Å; L253-L267 HydrophobicContact CD2-CD1 3.63Å; L253-L267 HydrophobicContact CG-CD1 3.57Å; I260-L267 HydrophobicContact CD1-CD1 3.94Å; P263-L267 WeakPolarHBondContact O-CB 3.39Å; P263-L267 PolarHBondContact O-N 3.16Å; L267-L269 PolarHBondContact O-N 3.28Å; L267-A270 PolarHBondContact O-N 3.2Å; L267-I271 HydrophobicContact CD1-CD1 4.34Å; L267-I271 HydrophobicContact CG-CD1 4.35Å; L267-I271 PolarHBondContact O-N 3.14Å
268	P	90.3	Very high	88.6	Confident	22 Å²	22	49 Å²	49	14%	0.143	25%	0.251	C	S	.	.	H	α-helix	trans	-67.1	-36.9	-179.9	-20.2	34.8	0	0	0	112.8	A99 T103 E264 R265 G272 L422	A99-P268 HydrophobicContact CB-CB 4.32Å; A99-P268 HydrophobicContact CB-CG 4.37Å; T103-P268 HydrophobicContact CG2-CG 4.07Å; E264-P268 WeakPolarHBondContact O-CD 3.37Å; E264-P268 WeakPolarHBondContact O-CG 3.47Å; R265-P268 WeakPolarHBondContact O-CD 3.3Å; P268-G272 PolarHBondContact O-N 3.2Å; P268-L422 HydrophobicContact CB-CD1 4.41Å; P268-L422 HydrophobicContact CB-CD2 4.07Å; P268-L422 HydrophobicContact CG-CD1 4.37Å; P268-L422 HydrophobicContact CG-CD2 3.9Å
269	L	91.1	Very high	89.4	Confident	72 Å²	72	47 Å²	47	38%	0.377	24%	0.243	S	C	.	.	H	α-helix	trans	-66.9	-41.1	177.3	-72.7	175.8	0	0	0	112.1	L47 R265 L267 I271 G272 I273	L47-L269 HydrophobicContact CD1-CB 3.69Å; L47-L269 HydrophobicContact CD2-CB 4.44Å; L47-L269 HydrophobicContact CD2-CD1 4.37Å; R265-L269 HydrophobicContact CG-CD1 3.68Å; R265-L269 WeakPolarHBondContact O-CB 3.37Å; R265-L269 WeakPolarHBondContact O-CD1 3.43Å; R265-L269 WeakPolarHBondContact O-CG 3.22Å; R265-L269 PolarHBondContact O-N 3.04Å; L267-L269 PolarHBondContact O-N 3.28Å; L269-I271 VanDerWaalsContact C-N 3.34Å; L269-I271 PolarHBondContact O-N 2.99Å; L269-G272 PolarHBondContact O-N 2.76Å; L269-I273 WeakPolarHBondContact O-CB 3.22Å; L269-I273 WeakPolarHBondContact O-CD1 3.48Å; L269-I273 VanDerWaalsContact O-CG1 3.27Å; L269-I273 WeakPolarHBondContact O-CG1 3.39Å; L269-I273 PolarHBondContact O-N 2.89Å
270	A	91.4	Very high	90	Very high	1 Å²	1	50.3 Å²	50.3	1%	0.008	26%	0.261	C	S	.	.	H	α-helix	trans	-61	-45.3	177.7	0	0	0	0	0	111	L47 V51 L253 N266 L267 S274	L47-A270 HydrophobicContact CD1-CB 4.01Å; V51-A270 HydrophobicContact CG2-CB 4.16Å; L253-A270 HydrophobicContact CD2-CB 3.51Å; N266-A270 WeakPolarHBondContact O-CB 3.22Å; N266-A270 PolarHBondContact O-N 3.08Å; L267-A270 PolarHBondContact O-N 3.2Å; A270-S274 VanDerWaalsContact O-CB 3.26Å; A270-S274 WeakPolarHBondContact O-CB 3.4Å; A270-S274 PolarHBondContact O-N 2.89Å; A270-S274 PolarHBondContact O-OG 3Å
271	I	90.4	Very high	90.4	Very high	2 Å²	2	51.5 Å²	51.5	1%	0.01	27%	0.267	C	S	.	.	H	α-helix	trans	-64.5	-47.4	176	-71.3	168.9	0	0	0	111.1	A95 A99 L267 L269 I273 S274 M275	A95-I271 HydrophobicContact CB-CG2 3.44Å; A95-I271 VanDerWaalsContact CB-CG2 3.44Å; A99-I271 HydrophobicContact CB-CD1 3.83Å; L267-I271 HydrophobicContact CD1-CD1 4.34Å; L267-I271 HydrophobicContact CG-CD1 4.35Å; L267-I271 PolarHBondContact O-N 3.14Å; L269-I271 VanDerWaalsContact C-N 3.34Å; L269-I271 PolarHBondContact O-N 2.99Å; I271-I273 PolarHBondContact O-N 3.32Å; I271-S274 WeakPolarHBondContact CA-OG 3.47Å; I271-S274 PolarHBondContact O-N 3Å; I271-S274 PolarHBondContact O-OG 3.27Å; I271-M275 HydrophobicContact CG2-CG 3.99Å; I271-M275 WeakPolarHBondContact O-CB 3.43Å; I271-M275 VanDerWaalsContact O-CG 3.29Å; I271-M275 WeakPolarHBondContact O-CG 3.44Å; I271-M275 PolarHBondContact O-N 3.29Å
272	G	90.1	Very high	90.8	Very high	41 Å²	41	46.8 Å²	46.8	42%	0.423	25%	0.247	S	C	.	.	H	α-helix	trans	-62.4	-27.7	-178.7	0	0	0	0	0	114.2	P268 L269 P276	P268-G272 PolarHBondContact O-N 3.2Å; L269-G272 PolarHBondContact O-N 2.76Å; G272-P276 WeakPolarHBondContact O-CD 3.27Å; G272-P276 WeakPolarHBondContact O-CG 3.23Å
273	I	92.1	Very high	91.3	Very high	75 Å²	75	43.4 Å²	43.4	39%	0.385	23%	0.228	S	C	.	.	H	α-helix	trans	-86.8	-45.6	176.1	-66.1	166.8	0	0	0	111.2	V51 L269 I271 P276 I277	V51-I273 HydrophobicContact CG1-CG2 4.12Å; V51-I273 HydrophobicContact CG2-CB 4.19Å; V51-I273 HydrophobicContact CG2-CD1 4.46Å; V51-I273 HydrophobicContact CG2-CG2 4.18Å; L269-I273 WeakPolarHBondContact O-CB 3.22Å; L269-I273 WeakPolarHBondContact O-CD1 3.48Å; L269-I273 VanDerWaalsContact O-CG1 3.27Å; L269-I273 WeakPolarHBondContact O-CG1 3.39Å; L269-I273 PolarHBondContact O-N 2.89Å; I271-I273 PolarHBondContact O-N 3.32Å; I273-P276 WeakPolarHBondContact O-CD 3.32Å; I273-I277 HydrophobicContact CG2-CD1 3.69Å; I273-I277 VanDerWaalsContact O-CD1 3.31Å; I273-I277 WeakPolarHBondContact O-CD1 3.48Å; I273-I277 VanDerWaalsContact O-CG1 3.25Å; I273-I277 WeakPolarHBondContact O-CG1 3.47Å
274	S	91.4	Very high	91.7	Very high	0 Å²	0	45 Å²	45	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-68.6	-42.2	-173.8	52.7	0	0	0	0	113.1	V54 A270 I271 I277 V278	V54-S274 WeakPolarHBondContact CG1-OG 3.02Å; A270-S274 VanDerWaalsContact O-CB 3.26Å; A270-S274 WeakPolarHBondContact O-CB 3.4Å; A270-S274 PolarHBondContact O-N 2.89Å; A270-S274 PolarHBondContact O-OG 3Å; I271-S274 WeakPolarHBondContact CA-OG 3.47Å; I271-S274 PolarHBondContact O-N 3Å; I271-S274 PolarHBondContact O-OG 3.27Å; S274-I277 PolarHBondContact O-N 3.26Å; S274-V278 WeakPolarHBondContact O-CG2 3.48Å; S274-V278 PolarHBondContact O-N 3.19Å
275	M	91.7	Very high	92.1	Very high	1 Å²	1	39 Å²	39	1%	0.005	21%	0.207	C	C	.	.	H	α-helix	trans	-62.9	-46.1	-174.3	-64.6	-59.6	-61	0	0	113.9	M58 V92 A95 W250 I271 I277 V278 T279	M58-M275 HydrophobicContact CE-CE 3.6Å; M58-M275 HydrophobicContact CE-SD 3.53Å; M58-M275 VanDerWaalsContact CE-SD 3.53Å; M58-M275 HydrophobicContact SD-CE 4.42Å; M58-M275 HydrophobicContact SD-SD 3.54Å; V92-M275 HydrophobicContact CG2-CB 3.64Å; V92-M275 HydrophobicContact CG2-CE 4.4Å; V92-M275 HydrophobicContact CG2-CG 4.48Å; A95-M275 HydrophobicContact CB-CG 4.05Å; A95-M275 HydrophobicContact CB-SD 4.19Å; W250-M275 HydrophobicContact CB-CE 4.42Å; W250-M275 HydrophobicContact CB-SD 3.54Å; W250-M275 VanDerWaalsContact CB-SD 3.54Å; W250-M275 HydrophobicContact CG-CE 4.33Å; W250-M275 HydrophobicContact CG-SD 4.04Å; I271-M275 HydrophobicContact CG2-CG 3.99Å; I271-M275 WeakPolarHBondContact O-CB 3.43Å; I271-M275 VanDerWaalsContact O-CG 3.29Å; I271-M275 WeakPolarHBondContact O-CG 3.44Å; I271-M275 PolarHBondContact O-N 3.29Å; M275-I277 VanDerWaalsContact C-N 3.35Å; M275-I277 PolarHBondContact O-N 2.88Å; M275-V278 PolarHBondContact O-N 3.27Å; M275-T279 WeakPolarHBondContact O-CB 3.48Å; M275-T279 PolarHBondContact O-N 3.15Å; M275-T279 PolarHBondContact O-OG1 3.48Å
276	P	91.8	Very high	92.5	Very high	71 Å²	71	30.4 Å²	30.4	46%	0.461	18%	0.175	S	C	.	.	H	α-helix	trans	-63.7	-38.2	174.4	-23.8	35.6	0	0	0	113.1	G272 I273 T279 L280	G272-P276 WeakPolarHBondContact O-CD 3.27Å; G272-P276 WeakPolarHBondContact O-CG 3.23Å; I273-P276 WeakPolarHBondContact O-CD 3.32Å; P276-T279 PolarHBondContact O-N 3.3Å; P276-L280 WeakPolarHBondContact O-CB 3.5Å; P276-L280 PolarHBondContact O-N 2.87Å
277	I	91.6	Very high	92.7	Very high	72 Å²	72	30.7 Å²	30.7	37%	0.369	18%	0.177	S	C	.	.	H	α-helix	trans	-60.8	-49.4	178.1	-70	171.1	0	0	0	110.3	I273 S274 M275 L280 I281	I273-I277 HydrophobicContact CG2-CD1 3.69Å; I273-I277 VanDerWaalsContact O-CD1 3.31Å; I273-I277 WeakPolarHBondContact O-CD1 3.48Å; I273-I277 VanDerWaalsContact O-CG1 3.25Å; I273-I277 WeakPolarHBondContact O-CG1 3.47Å; S274-I277 PolarHBondContact O-N 3.26Å; M275-I277 VanDerWaalsContact C-N 3.35Å; M275-I277 PolarHBondContact O-N 2.88Å; I277-L280 PolarHBondContact O-N 3.49Å; I277-I281 HydrophobicContact CG2-CD1 3.74Å; I277-I281 VanDerWaalsContact O-CG1 3.29Å; I277-I281 WeakPolarHBondContact O-CG1 3.17Å; I277-I281 PolarHBondContact O-N 3.16Å
278	V	92.5	Very high	93.1	Very high	0 Å²	0	30.8 Å²	30.8	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-63.8	-44	179.9	175.4	0	0	0	0	111	V55 M58 I59 Y247 S274 M275 L280 I281 Y282	V55-V278 HydrophobicContact CG1-CG2 4.44Å; V55-V278 HydrophobicContact CG2-CG2 4.22Å; M58-V278 HydrophobicContact CB-CG1 4.22Å; M58-V278 HydrophobicContact CB-CG2 4.26Å; M58-V278 HydrophobicContact CE-CB 4.19Å; M58-V278 HydrophobicContact CE-CG1 3.81Å; M58-V278 HydrophobicContact CE-CG2 4.44Å; M58-V278 HydrophobicContact SD-CB 4.41Å; M58-V278 HydrophobicContact SD-CG1 4.4Å; M58-V278 HydrophobicContact SD-CG2 4.02Å; I59-V278 HydrophobicContact CD1-CG2 4.29Å; I59-V278 HydrophobicContact CG1-CG1 4.32Å; I59-V278 HydrophobicContact CG1-CG2 4.06Å; Y247-V278 HydrophobicContact CD1-CG1 4.21Å; Y247-V278 HydrophobicContact CE1-CG1 4.19Å; S274-V278 WeakPolarHBondContact O-CG2 3.48Å; S274-V278 PolarHBondContact O-N 3.19Å; M275-V278 PolarHBondContact O-N 3.27Å; V278-L280 VanDerWaalsContact C-N 3.33Å; V278-L280 PolarHBondContact O-N 3.45Å; V278-I281 PolarHBondContact O-N 3.12Å; V278-Y282 HydrophobicContact CG1-CD1 4.32Å; V278-Y282 HydrophobicContact CG1-CD2 3.87Å; V278-Y282 HydrophobicContact CG1-CE1 3.97Å; V278-Y282 HydrophobicContact CG1-CE2 3.48Å; V278-Y282 VanDerWaalsContact CG1-CE2 3.48Å; V278-Y282 HydrophobicContact CG1-CG 4.29Å; V278-Y282 PolarHBondContact O-N 3.46Å
279	T	93.4	Very high	93.3	Very high	22 Å²	22	29.7 Å²	29.7	14%	0.135	17%	0.171	C	C	.	.	H	α-helix	trans	-58.5	-45.4	177.2	-55.6	0	0	0	0	111.6	M275 P276 Y282 I283	M275-T279 WeakPolarHBondContact O-CB 3.48Å; M275-T279 PolarHBondContact O-N 3.15Å; M275-T279 PolarHBondContact O-OG1 3.48Å; P276-T279 PolarHBondContact O-N 3.3Å; T279-Y282 PolarHBondContact O-N 3.41Å; T279-I283 HydrophobicContact CG2-CD1 4Å; T279-I283 WeakPolarHBondContact O-CG1 3.11Å; T279-I283 PolarHBondContact O-N 3.38Å
280	L	93.8	Very high	93.4	Very high	104 Å²	104	26.3 Å²	26.3	55%	0.545	15%	0.153	S	C	.	.	H	α-helix	trans	-63.4	-45.9	177.3	-177.8	63.4	0	0	0	111.5	P276 I277 V278 Y282 I283 L284	P276-L280 WeakPolarHBondContact O-CB 3.5Å; P276-L280 PolarHBondContact O-N 2.87Å; I277-L280 PolarHBondContact O-N 3.49Å; V278-L280 VanDerWaalsContact C-N 3.33Å; V278-L280 PolarHBondContact O-N 3.45Å; L280-Y282 VanDerWaalsContact C-N 3.33Å; L280-Y282 PolarHBondContact O-N 2.85Å; L280-I283 PolarHBondContact O-N 3.33Å; L280-L284 HydrophobicContact CD1-CD1 3.92Å; L280-L284 HydrophobicContact CD1-CG 4.06Å; L280-L284 HydrophobicContact CG-CD1 3.83Å; L280-L284 HydrophobicContact CG-CG 4.34Å; L280-L284 VanDerWaalsContact O-CB 3.32Å; L280-L284 WeakPolarHBondContact O-CB 3.09Å; L280-L284 VanDerWaalsContact O-CG 3.22Å; L280-L284 WeakPolarHBondContact O-CG 3.3Å; L280-L284 PolarHBondContact O-N 3.44Å
281	I	93.6	Very high	93.6	Very high	28 Å²	28	26.5 Å²	26.5	14%	0.144	15%	0.154	C	C	.	.	H	α-helix	trans	-59.4	-44.8	178.1	-71.7	168.8	0	0	0	110.6	I59 L203 I207 I277 V278 L284 T285	I59-I281 HydrophobicContact CD1-CD1 3.73Å; I59-I281 HydrophobicContact CD1-CG2 4.33Å; L203-I281 HydrophobicContact CB-CG2 4.48Å; L203-I281 HydrophobicContact CD1-CG2 4.09Å; I207-I281 HydrophobicContact CD1-CG2 4.15Å; I277-I281 HydrophobicContact CG2-CD1 3.74Å; I277-I281 VanDerWaalsContact O-CG1 3.29Å; I277-I281 WeakPolarHBondContact O-CG1 3.17Å; I277-I281 PolarHBondContact O-N 3.16Å; V278-I281 PolarHBondContact O-N 3.12Å; I281-L284 PolarHBondContact O-N 3.03Å; I281-T285 VanDerWaalsContact O-CB 3.29Å; I281-T285 WeakPolarHBondContact O-CB 3.33Å; I281-T285 PolarHBondContact O-N 3.41Å; I281-T285 PolarHBondContact O-OG1 3.28Å
282	Y	94.9	Very high	93.7	Very high	0 Å²	0	27.6 Å²	27.6	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-67.4	-44.4	-179.1	-70.9	-5.2	0	0	0	112.7	M58 I59 I63 W84 S246 Y247 V278 T279 L280 T285 N286	M58-Y282 VanDerWaalsContact C-OH 3.28Å; M58-Y282 PolarHBondContact O-OH 3.01Å; I59-Y282 WeakPolarHBondContact CA-OH 3.45Å; I59-Y282 HydrophobicContact CG1-CE1 4.16Å; I63-Y282 HydrophobicContact CB-CD1 4.07Å; I63-Y282 HydrophobicContact CB-CE1 3.73Å; I63-Y282 HydrophobicContact CD1-CD1 3.59Å; I63-Y282 HydrophobicContact CD1-CE1 4.14Å; I63-Y282 HydrophobicContact CD1-CG 3.82Å; I63-Y282 HydrophobicContact CG1-CD1 3.7Å; I63-Y282 HydrophobicContact CG1-CE1 3.9Å; I63-Y282 HydrophobicContact CG1-CG 4.43Å; I63-Y282 HydrophobicContact CG2-CE1 4.31Å; W84-Y282 HydrophobicContact CE3-CD2 4.02Å; W84-Y282 HydrophobicContact CE3-CG 4.31Å; W84-Y282 HydrophobicContact CH2-CD2 4.47Å; W84-Y282 AromaticContact CZ3-CD2 3.47Å; W84-Y282 HydrophobicContact CZ3-CD2 3.47Å; W84-Y282 VanDerWaalsContact CZ3-CD2 3.47Å; W84-Y282 HydrophobicContact CZ3-CE2 4.15Å; W84-Y282 AromaticContact CZ3-CG 3.87Å; W84-Y282 HydrophobicContact CZ3-CG 3.87Å; S246-Y282 WeakPolarHBondContact O-CE2 3.49Å; S246-Y282 PolarHBondContact O-OH 2.84Å; Y247-Y282 AromaticContact CD1-CD2 3.87Å; Y247-Y282 HydrophobicContact CD1-CD2 3.87Å; Y247-Y282 AromaticContact CD1-CE2 3.85Å; Y247-Y282 HydrophobicContact CD1-CE2 3.85Å; Y247-Y282 HydrophobicContact CD2-CD2 4.41Å; Y247-Y282 AromaticContact CE1-CD2 3.45Å; Y247-Y282 HydrophobicContact CE1-CD2 3.45Å; Y247-Y282 VanDerWaalsContact CE1-CD2 3.45Å; Y247-Y282 AromaticContact CE1-CE2 3.92Å; Y247-Y282 HydrophobicContact CE1-CE2 3.92Å; Y247-Y282 HydrophobicContact CE1-CG 4.44Å; Y247-Y282 HydrophobicContact CE2-CD2 4.05Å; Y247-Y282 HydrophobicContact CG-CD2 4.33Å; Y247-Y282 HydrophobicContact CG-CE2 4.22Å; Y247-Y282 AromaticContact CZ-CD2 3.56Å; V278-Y282 HydrophobicContact CG1-CD1 4.32Å; V278-Y282 HydrophobicContact CG1-CD2 3.87Å; V278-Y282 HydrophobicContact CG1-CE1 3.97Å; V278-Y282 HydrophobicContact CG1-CE2 3.48Å; V278-Y282 VanDerWaalsContact CG1-CE2 3.48Å; V278-Y282 HydrophobicContact CG1-CG 4.29Å; V278-Y282 PolarHBondContact O-N 3.46Å; T279-Y282 PolarHBondContact O-N 3.41Å; L280-Y282 VanDerWaalsContact C-N 3.33Å; L280-Y282 PolarHBondContact O-N 2.85Å; Y282-T285 PolarHBondContact O-N 3.44Å; Y282-N286 PolarHBondContact O-N 3.3Å; Y282-N286 PolarHBondContact O-ND2 2.93Å
283	I	95.5	Very high	93.8	Very high	49 Å²	49	25.6 Å²	25.6	25%	0.251	14%	0.141	S	C	.	.	H	α-helix	trans	-60.7	-48.7	175.2	-68.8	173	0	0	0	110.1	W84 A85 T279 L280 T285 N286 V287	W84-I283 HydrophobicContact CB-CG1 4.42Å; A85-I283 HydrophobicContact CB-CD1 4.12Å; T279-I283 HydrophobicContact CG2-CD1 4Å; T279-I283 WeakPolarHBondContact O-CG1 3.11Å; T279-I283 PolarHBondContact O-N 3.38Å; L280-I283 PolarHBondContact O-N 3.33Å; I283-T285 VanDerWaalsContact C-N 3.3Å; I283-T285 PolarHBondContact O-N 3.24Å; I283-N286 PolarHBondContact O-N 2.91Å; I283-V287 HydrophobicContact CG2-CG2 4.41Å; I283-V287 WeakPolarHBondContact O-CG2 3.41Å; I283-V287 PolarHBondContact O-N 3Å
284	L	95.8	Very high	93.9	Very high	55 Å²	55	25.4 Å²	25.4	29%	0.288	14%	0.14	S	C	.	.	H	α-helix	trans	-63.5	-35	179.7	-70.5	177.3	0	0	0	112.8	I207 L280 I281 V287 A288	I207-L284 HydrophobicContact CD1-CB 3.99Å; I207-L284 HydrophobicContact CG1-CB 3.98Å; I207-L284 HydrophobicContact CG2-CB 3.97Å; I207-L284 HydrophobicContact CG2-CD1 4.17Å; L280-L284 HydrophobicContact CD1-CD1 3.92Å; L280-L284 HydrophobicContact CD1-CG 4.06Å; L280-L284 HydrophobicContact CG-CD1 3.83Å; L280-L284 HydrophobicContact CG-CG 4.34Å; L280-L284 VanDerWaalsContact O-CB 3.32Å; L280-L284 WeakPolarHBondContact O-CB 3.09Å; L280-L284 VanDerWaalsContact O-CG 3.22Å; L280-L284 WeakPolarHBondContact O-CG 3.3Å; L280-L284 PolarHBondContact O-N 3.44Å; I281-L284 PolarHBondContact O-N 3.03Å; L284-V287 PolarHBondContact O-N 2.92Å; L284-A288 WeakPolarHBondContact O-CB 3.17Å; L284-A288 PolarHBondContact O-N 3.28Å
285	T	95.4	Very high	93.9	Very high	0 Å²	0	27.8 Å²	27.8	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-66.9	-43.2	176.2	-57.6	0	0	0	0	111	I63 L203 I206 I281 Y282 I283 A288 Y289	I63-T285 HydrophobicContact CD1-CG2 4.42Å; I63-T285 HydrophobicContact CG1-CG2 4.04Å; L203-T285 HydrophobicContact CD2-CG2 4.03Å; I206-T285 HydrophobicContact CG2-CG2 4.23Å; I281-T285 VanDerWaalsContact O-CB 3.29Å; I281-T285 WeakPolarHBondContact O-CB 3.33Å; I281-T285 PolarHBondContact O-N 3.41Å; I281-T285 PolarHBondContact O-OG1 3.28Å; Y282-T285 PolarHBondContact O-N 3.44Å; I283-T285 VanDerWaalsContact C-N 3.3Å; I283-T285 PolarHBondContact O-N 3.24Å; T285-A288 WeakPolarHBondContact O-CB 3.36Å; T285-A288 PolarHBondContact O-N 3.1Å; T285-Y289 HydrophobicContact CG2-CD2 4.28Å; T285-Y289 HydrophobicContact CG2-CE1 4.39Å; T285-Y289 HydrophobicContact CG2-CE2 3.65Å; T285-Y289 PolarHBondContact O-N 3.22Å
286	N	96	Very high	93.8	Very high	0 Å²	0	31.2 Å²	31.2	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-67.6	-39.6	176.1	-76	-84.7	0	0	0	111.8	L81 W84 Y282 I283 A288 Y289 Y290	L81-N286 HydrophobicContact CD2-CB 3.8Å; W84-N286 WeakPolarHBondContact CZ2-ND2 3.25Å; W84-N286 VanDerWaalsContact NE1-CG 3.31Å; W84-N286 PolarHBondContact NE1-ND2 2.94Å; W84-N286 PolarHBondContact NE1-OD1 3.43Å; W84-N286 VanDerWaalsContact NE1-OD1 3.09Å; Y282-N286 PolarHBondContact O-N 3.3Å; Y282-N286 PolarHBondContact O-ND2 2.93Å; I283-N286 PolarHBondContact O-N 2.91Å; N286-A288 VanDerWaalsContact C-N 3.28Å; N286-A288 PolarHBondContact O-N 3.49Å; N286-Y289 PolarHBondContact O-N 3.38Å; N286-Y290 HydrophobicContact CB-CE2 4.07Å; N286-Y290 VanDerWaalsContact O-CD2 3.31Å; N286-Y290 WeakPolarHBondContact O-CD2 3.5Å; N286-Y290 PolarHBondContact O-N 3.46Å; N286-Y290 PolarHBondContact OD1-OH 3.46Å
287	V	95.7	Very high	93.8	Very high	30 Å²	30	29.7 Å²	29.7	18%	0.182	17%	0.165	C	C	.	.	H	α-helix	trans	-57.3	-44.9	171	170.8	0	0	0	0	110.3	L81 F222 I283 L284 Y289 Y290 T291	L81-V287 HydrophobicContact CD1-CG2 4.05Å; L81-V287 HydrophobicContact CD2-CG2 3.92Å; F222-V287 HydrophobicContact CZ-CG1 4.12Å; I283-V287 HydrophobicContact CG2-CG2 4.41Å; I283-V287 WeakPolarHBondContact O-CG2 3.41Å; I283-V287 PolarHBondContact O-N 3Å; L284-V287 PolarHBondContact O-N 2.92Å; V287-Y289 PolarHBondContact O-N 2.86Å; V287-Y290 PolarHBondContact O-N 3.41Å; V287-T291 HydrophobicContact CG1-CG2 4.41Å; V287-T291 VanDerWaalsContact O-CG2 3.28Å; V287-T291 WeakPolarHBondContact O-CG2 3.37Å; V287-T291 PolarHBondContact O-N 3.03Å
288	A	95.8	Very high	93.8	Very high	1 Å²	1	26.3 Å²	26.3	1%	0.008	15%	0.147	C	C	.	.	H	α-helix	trans	-61.3	-42	176.1	0	0	0	0	0	112.6	I206 L284 T285 N286 Y290 T291 F308	I206-A288 HydrophobicContact CG2-CB 4.01Å; L284-A288 WeakPolarHBondContact O-CB 3.17Å; L284-A288 PolarHBondContact O-N 3.28Å; T285-A288 WeakPolarHBondContact O-CB 3.36Å; T285-A288 PolarHBondContact O-N 3.1Å; N286-A288 VanDerWaalsContact C-N 3.28Å; N286-A288 PolarHBondContact O-N 3.49Å; A288-Y290 PolarHBondContact O-N 3.13Å; A288-T291 PolarHBondContact O-OG1 3.38Å; A288-F308 WeakPolarHBondContact O-CE2 3.34Å
289	Y	95	Very high	93.8	Very high	0 Å²	0	29.3 Å²	29.3	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-62.4	-43.7	174.7	-66	-30.8	0	0	0	112	P67 I206 T285 N286 V287 T291 V292 L293 V304 A305 F308	P67-Y289 HydrophobicContact CB-CD2 4.28Å; P67-Y289 HydrophobicContact CG-CD2 4.16Å; P67-Y289 HydrophobicContact CG-CE2 3.95Å; I206-Y289 HydrophobicContact CD1-CE1 4.39Å; I206-Y289 HydrophobicContact CG2-CD1 4.28Å; I206-Y289 HydrophobicContact CG2-CE1 3.78Å; T285-Y289 HydrophobicContact CG2-CD2 4.28Å; T285-Y289 HydrophobicContact CG2-CE1 4.39Å; T285-Y289 HydrophobicContact CG2-CE2 3.65Å; T285-Y289 PolarHBondContact O-N 3.22Å; N286-Y289 PolarHBondContact O-N 3.38Å; V287-Y289 PolarHBondContact O-N 2.86Å; Y289-T291 VanDerWaalsContact C-N 3.34Å; Y289-T291 PolarHBondContact O-N 3.38Å; Y289-V292 PolarHBondContact O-N 3.35Å; Y289-L293 WeakPolarHBondContact O-CB 3.5Å; Y289-L293 PolarHBondContact O-N 2.91Å; Y289-V304 HydrophobicContact CD1-CG1 4.33Å; Y289-V304 HydrophobicContact CD2-CG1 3.98Å; Y289-V304 HydrophobicContact CE2-CG1 4.17Å; Y289-V304 HydrophobicContact CG-CG1 4.08Å; Y289-A305 HydrophobicContact CE1-CB 4.18Å; Y289-A305 VanDerWaalsContact OH-CB 3.27Å; Y289-A305 WeakPolarHBondContact OH-CB 3.17Å; Y289-F308 HydrophobicContact CD1-CB 3.89Å; Y289-F308 AromaticContact CD1-CD2 3.9Å; Y289-F308 HydrophobicContact CD1-CD2 3.9Å; Y289-F308 AromaticContact CD1-CG 3.88Å; Y289-F308 HydrophobicContact CD1-CG 3.88Å; Y289-F308 HydrophobicContact CE1-CB 4Å; Y289-F308 HydrophobicContact CE1-CG 4.12Å
290	Y	94.6	Very high	93.6	Very high	0 Å²	0	32 Å²	32	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-76.1	-17.8	-175.7	-55.9	-22.4	0	0	0	114	L71 Y77 S80 L81 H221 N286 V287 A288 V292	L71-Y290 HydrophobicContact CD1-CE1 4.4Å; L71-Y290 HydrophobicContact CD2-CE1 4.2Å; Y77-Y290 AromaticContact CD1-CD1 3.55Å; Y77-Y290 HydrophobicContact CD1-CD1 3.55Å; Y77-Y290 AromaticContact CD1-CD2 3.83Å; Y77-Y290 HydrophobicContact CD1-CD2 3.83Å; Y77-Y290 AromaticContact CD1-CE1 4Å; Y77-Y290 HydrophobicContact CD1-CE1 4Å; Y77-Y290 HydrophobicContact CD1-CE2 4.22Å; Y77-Y290 AromaticContact CD1-CG 3.48Å; Y77-Y290 HydrophobicContact CD1-CG 3.48Å; Y77-Y290 VanDerWaalsContact CD1-CG 3.48Å; Y77-Y290 AromaticContact CE1-CD1 3.82Å; Y77-Y290 HydrophobicContact CE1-CD1 3.82Å; Y77-Y290 HydrophobicContact CE1-CE1 4.4Å; Y77-Y290 HydrophobicContact CE1-CG 4.06Å; Y77-Y290 HydrophobicContact CG-CD2 4.16Å; Y77-Y290 HydrophobicContact CG-CG 4.06Å; S80-Y290 PolarHBondContact OG-OH 3.19Å; L81-Y290 HydrophobicContact CD2-CD2 4.31Å; L81-Y290 HydrophobicContact CD2-CE2 4.11Å; L81-Y290 HydrophobicContact CG-CD2 4.29Å; L81-Y290 HydrophobicContact CG-CE2 4.14Å; H221-Y290 WeakPolarHBondContact CB-O 3.42Å; H221-Y290 PolarHBondContact ND1-O 3.15Å; N286-Y290 HydrophobicContact CB-CE2 4.07Å; N286-Y290 VanDerWaalsContact O-CD2 3.31Å; N286-Y290 WeakPolarHBondContact O-CD2 3.5Å; N286-Y290 PolarHBondContact O-N 3.46Å; N286-Y290 PolarHBondContact OD1-OH 3.46Å; V287-Y290 PolarHBondContact O-N 3.41Å; A288-Y290 PolarHBondContact O-N 3.13Å; Y290-V292 PolarHBondContact O-N 3.23Å
291	T	94	Very high	93.3	Very high	6 Å²	6	27.4 Å²	27.4	4%	0.037	16%	0.159	C	C	.	.	H	α-helix	trans	-70.5	-21.2	171.1	57.1	0	0	0	0	113.1	L214 F222 V287 A288 Y289	L214-T291 HydrophobicContact CB-CG2 4.03Å; L214-T291 HydrophobicContact CD1-CG2 3.95Å; L214-T291 HydrophobicContact CG-CG2 4.47Å; F222-T291 HydrophobicContact CE2-CG2 3.48Å; F222-T291 VanDerWaalsContact CE2-CG2 3.48Å; F222-T291 HydrophobicContact CZ-CG2 3.94Å; V287-T291 HydrophobicContact CG1-CG2 4.41Å; V287-T291 VanDerWaalsContact O-CG2 3.28Å; V287-T291 WeakPolarHBondContact O-CG2 3.37Å; V287-T291 PolarHBondContact O-N 3.03Å; A288-T291 PolarHBondContact O-OG1 3.38Å; Y289-T291 VanDerWaalsContact C-N 3.34Å; Y289-T291 PolarHBondContact O-N 3.38Å
292	V	92.8	Very high	92.8	Very high	24 Å²	24	29.2 Å²	29.2	15%	0.145	17%	0.169	C	C	.	.	H	α-helix	trans	-117.9	-45.1	-172.5	175.8	0	0	0	0	111.9	K213 Y289 Y290 F308 Q311 T312	K213-V292 HydrophobicContact CB-CG2 4.24Å; K213-V292 HydrophobicContact CG-CG2 3.98Å; Y289-V292 PolarHBondContact O-N 3.35Å; Y290-V292 PolarHBondContact O-N 3.23Å; V292-F308 HydrophobicContact CB-CD2 3.88Å; V292-F308 HydrophobicContact CB-CE2 3.76Å; V292-F308 HydrophobicContact CG1-CD2 4.2Å; V292-F308 HydrophobicContact CG1-CE2 4.35Å; V292-F308 HydrophobicContact CG2-CD2 4.13Å; V292-F308 HydrophobicContact CG2-CE2 3.49Å; V292-F308 VanDerWaalsContact CG2-CE2 3.49Å; V292-F308 HydrophobicContact CG2-CZ 4.34Å; V292-Q311 HydrophobicContact CG1-CB 3.93Å; V292-T312 HydrophobicContact CB-CG2 4.33Å; V292-T312 HydrophobicContact CG1-CG2 3.72Å; V292-T312 HydrophobicContact CG2-CG2 3.77Å
293	L	93	Very high	92.6	Very high	0 Å²	0	29.2 Å²	29.2	0%	0	17%	0.169	C	C	.	.			trans	-93.6	141.1	-171.8	-58.3	-179.6	0	0	0	111.5	Y77 H221 Y289 D297 V298 V304 T307 F308	Y77-L293 PolarHBondContact OH-O 3.35Å; H221-L293 PolarHBondContact CE1-O 3.34Å; H221-L293 PolarHBondContact ND1-O 2.84Å; Y289-L293 WeakPolarHBondContact O-CB 3.5Å; Y289-L293 PolarHBondContact O-N 2.91Å; L293-D297 HydrophobicContact CB-CB 4.38Å; L293-D297 HydrophobicContact CD2-CB 4.46Å; L293-V298 HydrophobicContact CB-CG2 3.74Å; L293-V298 HydrophobicContact CD1-CG2 4Å; L293-V304 HydrophobicContact CD1-CG1 3.8Å; L293-T307 HydrophobicContact CD2-CG2 3.89Å; L293-F308 HydrophobicContact CD1-CB 4.13Å
294	N	92.9	Very high	92.4	Very high	70 Å²	70	27 Å²	27	37%	0.374	16%	0.158	S	C	.	.			trans	-76.6	161.1	167.8	-62	-65.8	0	0	0	111.2	Y77 H221 S296 D297 V298	Y77-N294 VanDerWaalsContact OH-C 3.25Å; Y77-N294 VanDerWaalsContact OH-CA 3.22Å; Y77-N294 WeakPolarHBondContact OH-CA 3.28Å; H221-N294 PolarHBondContact CE1-OD1 2.9Å; H221-N294 PolarHBondContact NE2-OD1 3.49Å; H221-N294 VanDerWaalsContact NE2-OD1 3.12Å; N294-S296 PolarHBondContact O-N 3.49Å; N294-D297 WeakPolarHBondContact CB-OD2 3.39Å; N294-D297 PolarHBondContact N-OD2 2.71Å; N294-D297 VanDerWaalsContact N-OD2 3.15Å; N294-D297 PolarHBondContact ND2-OD2 3.35Å; N294-D297 VanDerWaalsContact ND2-OD2 3.09Å; N294-D297 PolarHBondContact O-N 3.3Å; N294-V298 PolarHBondContact O-N 2.91Å
295	I	91.4	Very high	92.2	Very high	51 Å²	51	24.3 Å²	24.3	26%	0.262	14%	0.144	S	C	.	.	H	α-helix	trans	-53.5	-47.2	173.6	-61.4	-176	0	0	0	109.4	L71 Y77 D297 V298 L299	L71-I295 HydrophobicContact CD2-CB 4.32Å; L71-I295 HydrophobicContact CD2-CG1 4.27Å; L71-I295 HydrophobicContact CD2-CG2 4.03Å; L71-I295 HydrophobicContact CG-CG2 4.31Å; Y77-I295 HydrophobicContact CD1-CG1 4.13Å; Y77-I295 HydrophobicContact CE1-CB 4.45Å; Y77-I295 HydrophobicContact CE1-CD1 4.28Å; Y77-I295 HydrophobicContact CE1-CG1 3.37Å; Y77-I295 HydrophobicContact CE2-CD1 4.45Å; Y77-I295 HydrophobicContact CE2-CG1 4.05Å; Y77-I295 WeakPolarHBondContact OH-CG1 3.17Å; Y77-I295 PolarHBondContact OH-N 3.34Å; I295-D297 VanDerWaalsContact C-N 3.28Å; I295-D297 PolarHBondContact O-N 2.96Å; I295-V298 PolarHBondContact O-N 3.16Å; I295-L299 HydrophobicContact CG2-CD1 3.65Å; I295-L299 HydrophobicContact CG2-CG 3.96Å; I295-L299 WeakPolarHBondContact O-CB 3.25Å; I295-L299 WeakPolarHBondContact O-CG 3.44Å; I295-L299 PolarHBondContact O-N 3.33Å
296	S	91.2	Very high	92	Very high	73 Å²	73	24.4 Å²	24.4	51%	0.51	14%	0.144	S	C	.	.	H	α-helix	trans	-54.8	-42.7	177.6	52.6	0	0	0	0	112.8	N294 L299 S300	N294-S296 PolarHBondContact O-N 3.49Å; S296-L299 PolarHBondContact O-N 3.44Å; S296-S300 WeakPolarHBondContact O-CB 3.31Å; S296-S300 PolarHBondContact O-N 2.99Å; S296-S300 PolarHBondContact O-OG 3.3Å; S296-S300 VanDerWaalsContact O-OG 3.05Å
297	D	91.1	Very high	91.7	Very high	39 Å²	39	25.8 Å²	25.8	21%	0.209	15%	0.153	C	C	.	.	H	α-helix	trans	-70	-38.6	-176	-54.2	-24.1	0	0	0	111.1	L293 N294 I295 S300 S301	L293-D297 HydrophobicContact CB-CB 4.38Å; L293-D297 HydrophobicContact CD2-CB 4.46Å; N294-D297 WeakPolarHBondContact CB-OD2 3.39Å; N294-D297 PolarHBondContact N-OD2 2.71Å; N294-D297 VanDerWaalsContact N-OD2 3.15Å; N294-D297 PolarHBondContact ND2-OD2 3.35Å; N294-D297 VanDerWaalsContact ND2-OD2 3.09Å; N294-D297 PolarHBondContact O-N 3.3Å; I295-D297 VanDerWaalsContact C-N 3.28Å; I295-D297 PolarHBondContact O-N 2.96Å; D297-S300 PolarHBondContact O-OG 2.72Å; D297-S301 WeakPolarHBondContact O-CB 3.48Å; D297-S301 PolarHBondContact O-N 3.22Å
298	V	91.8	Very high	91.6	Very high	0 Å²	0	24.3 Å²	24.3	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-67.5	-40.2	174.4	177.9	0	0	0	0	110.8	K68 L71 L293 N294 I295 V304	K68-V298 HydrophobicContact CB-CG1 4.49Å; L71-V298 HydrophobicContact CD2-CB 3.81Å; L71-V298 HydrophobicContact CD2-CG1 3.75Å; L71-V298 HydrophobicContact CD2-CG2 4.25Å; L293-V298 HydrophobicContact CB-CG2 3.74Å; L293-V298 HydrophobicContact CD1-CG2 4Å; N294-V298 PolarHBondContact O-N 2.91Å; I295-V298 PolarHBondContact O-N 3.16Å; V298-V304 HydrophobicContact CG1-CG1 4.34Å; V298-V304 HydrophobicContact CG1-CG2 4.17Å; V298-V304 HydrophobicContact CG2-CG1 4.42Å
299	L	91.7	Very high	91.4	Very high	64 Å²	64	24.3 Å²	24.3	34%	0.335	14%	0.144	S	C	.	.	H	α-helix	trans	-74.2	-34.2	-177.8	-66.9	-172.5	0	0	0	113	K68 L71 V72 I295 S296	K68-L299 WeakPolarHBondContact CE-O 3.4Å; K68-L299 PolarHBondContact NZ-O 3.08Å; K68-L299 VanDerWaalsContact NZ-O 3.16Å; L71-L299 HydrophobicContact CB-CD2 4.33Å; V72-L299 HydrophobicContact CB-CD2 4.22Å; V72-L299 HydrophobicContact CG2-CD2 3.4Å; V72-L299 VanDerWaalsContact CG2-CD2 3.4Å; I295-L299 HydrophobicContact CG2-CD1 3.65Å; I295-L299 HydrophobicContact CG2-CG 3.96Å; I295-L299 WeakPolarHBondContact O-CB 3.25Å; I295-L299 WeakPolarHBondContact O-CG 3.44Å; I295-L299 PolarHBondContact O-N 3.33Å; S296-L299 PolarHBondContact O-N 3.44Å
300	S	89.3	Confident	91.2	Very high	77 Å²	77	28.4 Å²	28.4	54%	0.538	17%	0.166	S	C	.	.	H	α-helix	trans	-80.3	-20.4	177.3	63.1	0	0	0	0	113.3	S296 D297	S296-S300 WeakPolarHBondContact O-CB 3.31Å; S296-S300 PolarHBondContact O-N 2.99Å; S296-S300 PolarHBondContact O-OG 3.3Å; S296-S300 VanDerWaalsContact O-OG 3.05Å; D297-S300 PolarHBondContact O-OG 2.72Å
301	S	88.1	Confident	91	Very high	8 Å²	8	32.8 Å²	32.8	6%	0.056	19%	0.186	C	C	.	.			trans	-86.4	131.6	-176.3	-176.5	0	0	0	0	112.5	K68 D297 A303 V304 T307	K68-S301 WeakPolarHBondContact CD-O 3.48Å; K68-S301 PolarHBondContact NZ-O 3.24Å; K68-S301 VanDerWaalsContact NZ-O 3.11Å; D297-S301 WeakPolarHBondContact O-CB 3.48Å; D297-S301 PolarHBondContact O-N 3.22Å; S301-A303 VanDerWaalsContact C-N 3.33Å; S301-A303 PolarHBondContact OG-N 3.03Å; S301-A303 VanDerWaalsContact OG-N 3.14Å; S301-A303 PolarHBondContact OG-O 3.24Å; S301-V304 PolarHBondContact OG-N 3.16Å; S301-T307 WeakPolarHBondContact CB-OG1 3.5Å; S301-T307 PolarHBondContact OG-OG1 3.3Å
302	D	83.8	Confident	90.8	Very high	66 Å²	66	33.6 Å²	33.6	35%	0.353	19%	0.191	S	C	.	.	S	Bend	trans	-87.2	-5.4	168	-74.8	-23.4	0	0	0	113.1	K68	K68-D302 IonicContact NZ-OD1 2.69Å; K68-D302 PolarHBondContact NZ-OD1 3.34Å
303	A	89.6	Confident	90.5	Very high	0 Å²	0	34.4 Å²	34.4	0%	0	19%	0.193	C	C	.	.	S	Bend	trans	-140.5	72.6	178.7	0	0	0	0	0	110.4	Y150 Q153 S301 A305 V306 T307	Y150-A303 HydrophobicContact CD1-CB 4.18Å; Y150-A303 HydrophobicContact CD2-CB 3.98Å; Y150-A303 HydrophobicContact CE1-CB 4.01Å; Y150-A303 HydrophobicContact CE2-CB 3.79Å; Y150-A303 HydrophobicContact CG-CB 4.19Å; Q153-A303 HydrophobicContact CB-CB 4.16Å; Q153-A303 HydrophobicContact CG-CB 4.13Å; S301-A303 VanDerWaalsContact C-N 3.33Å; S301-A303 PolarHBondContact OG-N 3.03Å; S301-A303 VanDerWaalsContact OG-N 3.14Å; S301-A303 PolarHBondContact OG-O 3.24Å; A303-A305 PolarHBondContact O-N 3.3Å; A303-A305 VanDerWaalsContact O-N 3.08Å; A303-V306 HydrophobicContact CB-CB 4.08Å; A303-V306 HydrophobicContact CB-CG2 3.85Å; A303-V306 WeakPolarHBondContact O-CA 3.47Å; A303-V306 WeakPolarHBondContact O-CB 3.15Å; A303-V306 PolarHBondContact O-N 3.35Å; A303-T307 PolarHBondContact O-N 3.07Å
304	V	91.6	Very high	90.1	Very high	2 Å²	2	36.8 Å²	36.8	1%	0.012	22%	0.217	C	C	.	.	H	α-helix	trans	-51.5	-39.6	-171.8	-178.7	0	0	0	0	112.6	K68 Y150 Y289 L293 V298 S301 V306 T307 F308	K68-V304 HydrophobicContact CB-CG2 4.33Å; Y150-V304 PolarHBondContact OH-N 2.92Å; Y289-V304 HydrophobicContact CD1-CG1 4.33Å; Y289-V304 HydrophobicContact CD2-CG1 3.98Å; Y289-V304 HydrophobicContact CE2-CG1 4.17Å; Y289-V304 HydrophobicContact CG-CG1 4.08Å; L293-V304 HydrophobicContact CD1-CG1 3.8Å; V298-V304 HydrophobicContact CG1-CG1 4.34Å; V298-V304 HydrophobicContact CG1-CG2 4.17Å; V298-V304 HydrophobicContact CG2-CG1 4.42Å; S301-V304 PolarHBondContact OG-N 3.16Å; V304-V306 VanDerWaalsContact C-N 3.34Å; V304-V306 PolarHBondContact O-N 3.46Å; V304-T307 PolarHBondContact O-N 3.47Å; V304-F308 PolarHBondContact O-N 2.99Å
305	A	91.5	Very high	89.6	Confident	0 Å²	0	41.5 Å²	41.5	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-71	-28.2	-179.8	0	0	0	0	0	113.4	F64 Y150 I206 Y289 A303 A309 I320	F64-A305 HydrophobicContact CD1-CB 3.81Å; F64-A305 HydrophobicContact CE1-CB 4.09Å; Y150-A305 HydrophobicContact CE1-CB 3.9Å; Y150-A305 PolarHBondContact OH-N 2.81Å; I206-A305 HydrophobicContact CD1-CB 4.07Å; Y289-A305 HydrophobicContact CE1-CB 4.18Å; Y289-A305 VanDerWaalsContact OH-CB 3.27Å; Y289-A305 WeakPolarHBondContact OH-CB 3.17Å; A303-A305 PolarHBondContact O-N 3.3Å; A303-A305 VanDerWaalsContact O-N 3.08Å; A305-A309 VanDerWaalsContact O-CB 3.31Å; A305-A309 WeakPolarHBondContact O-CB 3.32Å; A305-A309 PolarHBondContact O-N 3.22Å; A305-I320 HydrophobicContact CB-CG2 3.93Å
306	V	90.6	Very high	89.2	Confident	1 Å²	1	45.4 Å²	45.4	1%	0.006	26%	0.255	C	S	.	.	H	α-helix	trans	-69.8	-45.4	173.2	-179.4	0	0	0	0	109.4	Y150 Q153 A303 V304 F308 A309 D310 P321	Y150-V306 HydrophobicContact CD1-CG2 3.59Å; Y150-V306 HydrophobicContact CE1-CG2 3.74Å; Q153-V306 HydrophobicContact CG-CB 4.46Å; Q153-V306 HydrophobicContact CG-CG1 4.15Å; A303-V306 HydrophobicContact CB-CB 4.08Å; A303-V306 HydrophobicContact CB-CG2 3.85Å; A303-V306 WeakPolarHBondContact O-CA 3.47Å; A303-V306 WeakPolarHBondContact O-CB 3.15Å; A303-V306 PolarHBondContact O-N 3.35Å; V304-V306 VanDerWaalsContact C-N 3.34Å; V304-V306 PolarHBondContact O-N 3.46Å; V306-F308 VanDerWaalsContact C-N 3.32Å; V306-F308 PolarHBondContact O-N 3.2Å; V306-A309 CarbonylContact O-C 3.32Å; V306-A309 WeakPolarHBondContact O-CA 3.18Å; V306-A309 WeakPolarHBondContact O-CB 3.13Å; V306-A309 PolarHBondContact O-N 3.12Å; V306-D310 PolarHBondContact O-N 3.33Å; V306-P321 HydrophobicContact CG2-CB 3.78Å; V306-P321 HydrophobicContact CG2-CG 4.35Å
307	T	91.1	Very high	88.8	Confident	29 Å²	29	42.4 Å²	42.4	18%	0.178	23%	0.233	C	C	.	.	H	α-helix	trans	-59.9	-42.6	175.8	-50.2	0	0	0	0	111.8	L293 S301 A303 V304 A309 D310 Q311	L293-T307 HydrophobicContact CD2-CG2 3.89Å; S301-T307 WeakPolarHBondContact CB-OG1 3.5Å; S301-T307 PolarHBondContact OG-OG1 3.3Å; A303-T307 PolarHBondContact O-N 3.07Å; V304-T307 PolarHBondContact O-N 3.47Å; T307-A309 VanDerWaalsContact C-N 3.31Å; T307-A309 PolarHBondContact O-N 2.88Å; T307-D310 PolarHBondContact O-N 3.4Å; T307-Q311 WeakPolarHBondContact O-CG 3.48Å; T307-Q311 PolarHBondContact O-N 3.42Å
308	F	93.1	Very high	88.6	Confident	0 Å²	0	48 Å²	48	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-58.9	-43.6	171.6	178.6	-95.1	0	0	0	111.7	I206 M209 A288 Y289 V292 L293 V304 V306 Q311 T312 F313	I206-F308 HydrophobicContact CB-CE1 4.28Å; I206-F308 HydrophobicContact CG1-CD1 4.29Å; I206-F308 HydrophobicContact CG1-CE1 4.32Å; I206-F308 HydrophobicContact CG2-CD1 4.13Å; I206-F308 HydrophobicContact CG2-CE1 3.87Å; I206-F308 HydrophobicContact CG2-CZ 4.31Å; M209-F308 HydrophobicContact CB-CE1 4.3Å; M209-F308 HydrophobicContact CB-CZ 4.24Å; A288-F308 WeakPolarHBondContact O-CE2 3.34Å; Y289-F308 HydrophobicContact CD1-CB 3.89Å; Y289-F308 AromaticContact CD1-CD2 3.9Å; Y289-F308 HydrophobicContact CD1-CD2 3.9Å; Y289-F308 AromaticContact CD1-CG 3.88Å; Y289-F308 HydrophobicContact CD1-CG 3.88Å; Y289-F308 HydrophobicContact CE1-CB 4Å; Y289-F308 HydrophobicContact CE1-CG 4.12Å; V292-F308 HydrophobicContact CB-CD2 3.88Å; V292-F308 HydrophobicContact CB-CE2 3.76Å; V292-F308 HydrophobicContact CG1-CD2 4.2Å; V292-F308 HydrophobicContact CG1-CE2 4.35Å; V292-F308 HydrophobicContact CG2-CD2 4.13Å; V292-F308 HydrophobicContact CG2-CE2 3.49Å; V292-F308 VanDerWaalsContact CG2-CE2 3.49Å; V292-F308 HydrophobicContact CG2-CZ 4.34Å; L293-F308 HydrophobicContact CD1-CB 4.13Å; V304-F308 PolarHBondContact O-N 2.99Å; V306-F308 VanDerWaalsContact C-N 3.32Å; V306-F308 PolarHBondContact O-N 3.2Å; F308-Q311 PolarHBondContact O-N 3.26Å; F308-T312 HydrophobicContact CD2-CG2 4.41Å; F308-T312 HydrophobicContact CE1-CG2 4.32Å; F308-T312 HydrophobicContact CE2-CG2 4.05Å; F308-T312 HydrophobicContact CZ-CG2 4.01Å; F308-T312 WeakPolarHBondContact O-CB 3.33Å; F308-T312 WeakPolarHBondContact O-CG2 3.44Å; F308-T312 PolarHBondContact O-N 3.16Å; F308-T312 PolarHBondContact O-OG1 3.38Å; F308-F313 HydrophobicContact CD1-CE2 4.4Å; F308-F313 AromaticContact CE1-CE2 3.98Å; F308-F313 HydrophobicContact CE1-CE2 3.98Å
309	A	91.7	Very high	88.4	Confident	0 Å²	0	50.3 Å²	50.3	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-65.6	-41.7	-178.3	0	0	0	0	0	112.7	A305 V306 T307 Q311 T312 F313 S317 I320	A305-A309 VanDerWaalsContact O-CB 3.31Å; A305-A309 WeakPolarHBondContact O-CB 3.32Å; A305-A309 PolarHBondContact O-N 3.22Å; V306-A309 CarbonylContact O-C 3.32Å; V306-A309 WeakPolarHBondContact O-CA 3.18Å; V306-A309 WeakPolarHBondContact O-CB 3.13Å; V306-A309 PolarHBondContact O-N 3.12Å; T307-A309 VanDerWaalsContact C-N 3.31Å; T307-A309 PolarHBondContact O-N 2.88Å; A309-Q311 VanDerWaalsContact C-N 3.29Å; A309-Q311 PolarHBondContact O-N 2.71Å; A309-T312 PolarHBondContact O-N 2.98Å; A309-F313 HydrophobicContact CB-CD2 4.27Å; A309-F313 PolarHBondContact O-N 2.6Å; A309-S317 VanDerWaalsContact C-OG 3.29Å; A309-S317 WeakPolarHBondContact CB-OG 3.36Å; A309-I320 HydrophobicContact CB-CB 3.8Å; A309-I320 HydrophobicContact CB-CG1 3.68Å; A309-I320 HydrophobicContact CB-CG2 4.22Å
310	D	89.9	Confident	88.3	Confident	86 Å²	86	47.4 Å²	47.4	46%	0.46	25%	0.251	S	S	.	.	H	α-helix	trans	-62.5	-36.5	178.8	-72.3	-28.9	0	0	0	111.9	V306 T307 S317	V306-D310 PolarHBondContact O-N 3.33Å; T307-D310 PolarHBondContact O-N 3.4Å; D310-S317 WeakPolarHBondContact CA-OG 3.5Å; D310-S317 PolarHBondContact N-OG 2.76Å; D310-S317 WeakPolarHBondContact OD1-CB 3.43Å; D310-S317 PolarHBondContact OD1-OG 3.42Å
311	Q	90	Very high	88.3	Confident	93 Å²	93	44 Å²	44	44%	0.435	23%	0.227	S	C	.	.	H	α-helix	trans	-81.2	-15.2	178.7	-64.2	-171.6	17.7	0	0	114.1	V292 T307 F308 A309	V292-Q311 HydrophobicContact CG1-CB 3.93Å; T307-Q311 WeakPolarHBondContact O-CG 3.48Å; T307-Q311 PolarHBondContact O-N 3.42Å; F308-Q311 PolarHBondContact O-N 3.26Å; A309-Q311 VanDerWaalsContact C-N 3.29Å; A309-Q311 PolarHBondContact O-N 2.71Å
312	T	91	Very high	88.3	Confident	23 Å²	23	47.7 Å²	47.7	14%	0.141	25%	0.245	C	C	.	.	H	α-helix	trans	-123.1	-45.1	-170.6	56.7	0	0	0	0	115.4	V292 F308 A309	V292-T312 HydrophobicContact CB-CG2 4.33Å; V292-T312 HydrophobicContact CG1-CG2 3.72Å; V292-T312 HydrophobicContact CG2-CG2 3.77Å; F308-T312 HydrophobicContact CD2-CG2 4.41Å; F308-T312 HydrophobicContact CE1-CG2 4.32Å; F308-T312 HydrophobicContact CE2-CG2 4.05Å; F308-T312 HydrophobicContact CZ-CG2 4.01Å; F308-T312 WeakPolarHBondContact O-CB 3.33Å; F308-T312 WeakPolarHBondContact O-CG2 3.44Å; F308-T312 PolarHBondContact O-N 3.16Å; F308-T312 PolarHBondContact O-OG1 3.38Å; A309-T312 PolarHBondContact O-N 2.98Å
313	F	86.1	Confident	88.5	Confident	40 Å²	40	45.3 Å²	45.3	18%	0.175	23%	0.234	C	C	.	.	T	Hydrogen-bonded Turn	trans	-89.4	-10.2	-171.1	-77.8	-92.4	0	0	0	113.5	A205 M209 F308 A309 M315 F316	A205-F313 HydrophobicContact CB-CE1 4.43Å; A205-F313 HydrophobicContact CB-CZ 4.06Å; M209-F313 HydrophobicContact CB-CE2 4.15Å; M209-F313 HydrophobicContact CB-CZ 4.08Å; M209-F313 HydrophobicContact CG-CD1 4.47Å; M209-F313 HydrophobicContact CG-CD2 4.48Å; M209-F313 HydrophobicContact CG-CE1 3.68Å; M209-F313 HydrophobicContact CG-CE2 3.71Å; M209-F313 HydrophobicContact CG-CZ 3.26Å; F308-F313 HydrophobicContact CD1-CE2 4.4Å; F308-F313 AromaticContact CE1-CE2 3.98Å; F308-F313 HydrophobicContact CE1-CE2 3.98Å; A309-F313 HydrophobicContact CB-CD2 4.27Å; A309-F313 PolarHBondContact O-N 2.6Å; F313-M315 PolarHBondContact O-N 3.16Å; F313-M315 VanDerWaalsContact O-N 3.1Å; F313-F316 HydrophobicContact CB-CB 4.16Å; F313-F316 HydrophobicContact CD1-CB 4.33Å; F313-F316 PolarHBondContact O-N 3.38Å
314	G	85.1	Confident	88.5	Confident	50 Å²	50	45.4 Å²	45.4	52%	0.515	24%	0.235	S	C	.	.	G	3₁₀ helix	trans	53.3	-116.3	179.7	0	0	0	0	0	111.5	F316 S317	G314-F316 PolarHBondContact O-N 3.01Å; G314-F316 VanDerWaalsContact O-N 3.13Å; G314-S317 WeakPolarHBondContact O-CB 3.33Å; G314-S317 PolarHBondContact O-N 3.48Å
315	M	82.1	Confident	88.4	Confident	170 Å²	170	45.5 Å²	45.5	84%	0.837	24%	0.236	S	C	*	.	G	3₁₀ helix	trans	-61.8	-20.8	-179.5	-172.4	169.6	-79.8	0	0	114.2	F313 W318	F313-M315 PolarHBondContact O-N 3.16Å; F313-M315 VanDerWaalsContact O-N 3.1Å; M315-W318 PolarHBondContact O-NE1 2.93Å
316	F	82.4	Confident	88.1	Confident	133 Å²	133	48.4 Å²	48.4	58%	0.583	25%	0.251	S	S	*	.	G	3₁₀ helix	trans	-91.5	4	177.3	-65	-74.7	0	0	0	113.7	F313 G314 W318 T319	F313-F316 HydrophobicContact CB-CB 4.16Å; F313-F316 HydrophobicContact CD1-CB 4.33Å; F313-F316 PolarHBondContact O-N 3.38Å; G314-F316 PolarHBondContact O-N 3.01Å; G314-F316 VanDerWaalsContact O-N 3.13Å; F316-W318 PolarHBondContact O-N 3.34Å; F316-T319 WeakPolarHBondContact O-CB 3.46Å; F316-T319 WeakPolarHBondContact O-CG2 3.31Å; F316-T319 PolarHBondContact O-N 3.37Å; F316-T319 PolarHBondContact O-OG1 3.22Å
317	S	84.2	Confident	88	Confident	9 Å²	9	48.4 Å²	48.4	6%	0.063	25%	0.251	C	S	.	.	T	Hydrogen-bonded Turn	trans	-54.9	-38.1	-177.7	-177.1	0	0	0	0	112.9	A309 D310 G314 T319 I320 P321	A309-S317 VanDerWaalsContact C-OG 3.29Å; A309-S317 WeakPolarHBondContact CB-OG 3.36Å; D310-S317 WeakPolarHBondContact CA-OG 3.5Å; D310-S317 PolarHBondContact N-OG 2.76Å; D310-S317 WeakPolarHBondContact OD1-CB 3.43Å; D310-S317 PolarHBondContact OD1-OG 3.42Å; G314-S317 WeakPolarHBondContact O-CB 3.33Å; G314-S317 PolarHBondContact O-N 3.48Å; S317-T319 PolarHBondContact O-N 3.29Å; S317-I320 PolarHBondContact O-N 3.05Å; S317-P321 WeakPolarHBondContact O-CD 3.21Å
318	W	85.2	Confident	87.9	Confident	157 Å²	157	47 Å²	47	60%	0.595	24%	0.243	S	C	*	.	T	Hydrogen-bonded Turn	trans	-59.7	-17.4	179.7	69	-90.9	0	0	0	114.9	M315 F316 P321 I322	M315-W318 PolarHBondContact O-NE1 2.93Å; F316-W318 PolarHBondContact O-N 3.34Å; W318-P321 WeakPolarHBondContact O-CD 3.19Å; W318-P321 WeakPolarHBondContact O-CG 3.41Å; W318-I322 HydrophobicContact CE3-CD1 3.55Å; W318-I322 HydrophobicContact CZ3-CD1 3.75Å; W318-I322 WeakPolarHBondContact O-CG1 3.26Å
319	T	87.9	Confident	87.6	Confident	48 Å²	48	49 Å²	49	29%	0.294	25%	0.251	S	S	.	.	H	α-helix	trans	-73.3	-36.1	-179.2	62.2	0	0	0	0	112.5	F316 S317 A323	F316-T319 WeakPolarHBondContact O-CB 3.46Å; F316-T319 WeakPolarHBondContact O-CG2 3.31Å; F316-T319 PolarHBondContact O-N 3.37Å; F316-T319 PolarHBondContact O-OG1 3.22Å; S317-T319 PolarHBondContact O-N 3.29Å; T319-A323 WeakPolarHBondContact O-CB 3.37Å; T319-A323 PolarHBondContact O-N 2.88Å
320	I	89.4	Confident	87.2	Confident	4 Å²	4	49.3 Å²	49.3	2%	0.021	26%	0.255	C	S	.	.	H	α-helix	trans	-64.9	-52.5	-179.5	-62.7	-61.4	0	0	0	112.9	I206 A305 A309 S317 I322 A323 V324	I206-I320 HydrophobicContact CD1-CD1 4.48Å; I206-I320 HydrophobicContact CG1-CD1 4.19Å; A305-I320 HydrophobicContact CB-CG2 3.93Å; A309-I320 HydrophobicContact CB-CB 3.8Å; A309-I320 HydrophobicContact CB-CG1 3.68Å; A309-I320 HydrophobicContact CB-CG2 4.22Å; S317-I320 PolarHBondContact O-N 3.05Å; I320-I322 VanDerWaalsContact C-N 3.26Å; I320-I322 PolarHBondContact O-N 3.25Å; I320-A323 PolarHBondContact O-N 3.32Å; I320-A323 VanDerWaalsContact O-N 3.12Å; I320-V324 HydrophobicContact CG2-CG2 4.21Å; I320-V324 WeakPolarHBondContact O-CG2 3.35Å; I320-V324 PolarHBondContact O-N 2.9Å
321	P	89.6	Confident	86.9	Confident	6 Å²	6	46.1 Å²	46.1	4%	0.039	24%	0.242	C	C	.	.	H	α-helix	trans	-58.3	-39.1	179.3	18.6	-28.5	0	0	0	112.3	Y150 P154 V306 S317 W318 V324 A325	Y150-P321 WeakPolarHBondContact O-CB 3.34Å; P154-P321 HydrophobicContact CG-CB 3.74Å; P154-P321 HydrophobicContact CG-CG 3.66Å; V306-P321 HydrophobicContact CG2-CB 3.78Å; V306-P321 HydrophobicContact CG2-CG 4.35Å; S317-P321 WeakPolarHBondContact O-CD 3.21Å; W318-P321 WeakPolarHBondContact O-CD 3.19Å; W318-P321 WeakPolarHBondContact O-CG 3.41Å; P321-V324 PolarHBondContact O-N 3.49Å; P321-A325 WeakPolarHBondContact O-CB 3.47Å; P321-A325 PolarHBondContact O-N 3.49Å
322	I	88.8	Confident	86.8	Confident	85 Å²	85	41.7 Å²	41.7	44%	0.436	22%	0.222	S	C	.	.	H	α-helix	trans	-64.6	-47.5	175.9	-64.2	-179.1	0	0	0	110.6	W318 I320 V324 A325 L326	W318-I322 HydrophobicContact CE3-CD1 3.55Å; W318-I322 HydrophobicContact CZ3-CD1 3.75Å; W318-I322 WeakPolarHBondContact O-CG1 3.26Å; I320-I322 VanDerWaalsContact C-N 3.26Å; I320-I322 PolarHBondContact O-N 3.25Å; I322-V324 VanDerWaalsContact C-N 3.32Å; I322-V324 PolarHBondContact O-N 2.93Å; I322-A325 PolarHBondContact O-N 3.49Å; I322-L326 HydrophobicContact CG2-CD1 4.01Å; I322-L326 HydrophobicContact CG2-CG 4.32Å; I322-L326 WeakPolarHBondContact O-CB 3.27Å; I322-L326 VanDerWaalsContact O-CG 3.27Å; I322-L326 WeakPolarHBondContact O-CG 3.49Å; I322-L326 PolarHBondContact O-N 3.43Å
323	A	88.3	Confident	86.6	Confident	16 Å²	16	40.9 Å²	40.9	13%	0.132	22%	0.216	C	C	.	.	H	α-helix	trans	-63	-39.7	-179.7	0	0	0	0	0	112.3	A202 T319 I320 S327	A202-A323 HydrophobicContact CB-CB 3.6Å; T319-A323 WeakPolarHBondContact O-CB 3.37Å; T319-A323 PolarHBondContact O-N 2.88Å; I320-A323 PolarHBondContact O-N 3.32Å; I320-A323 VanDerWaalsContact O-N 3.12Å; A323-S327 WeakPolarHBondContact O-CB 3.39Å; A323-S327 PolarHBondContact O-N 2.79Å
324	V	88.4	Confident	86.3	Confident	1 Å²	1	39.7 Å²	39.7	1%	0.006	21%	0.214	C	C	.	.	H	α-helix	trans	-68.1	-41.7	175.4	178.2	0	0	0	0	111.5	F64 Y150 I320 P321 I322 L326 S327 C328	F64-V324 HydrophobicContact CB-CG1 4.13Å; F64-V324 HydrophobicContact CD1-CG1 4.12Å; F64-V324 HydrophobicContact CD1-CG2 3.78Å; F64-V324 HydrophobicContact CD2-CB 4.48Å; F64-V324 HydrophobicContact CD2-CG1 3.55Å; F64-V324 HydrophobicContact CD2-CG2 4.24Å; F64-V324 HydrophobicContact CE1-CG1 4.48Å; F64-V324 HydrophobicContact CE1-CG2 3.49Å; F64-V324 VanDerWaalsContact CE1-CG2 3.49Å; F64-V324 HydrophobicContact CE2-CB 4.45Å; F64-V324 HydrophobicContact CE2-CG1 3.96Å; F64-V324 HydrophobicContact CE2-CG2 3.98Å; F64-V324 HydrophobicContact CG-CG1 3.65Å; F64-V324 HydrophobicContact CG-CG2 4.15Å; F64-V324 HydrophobicContact CZ-CG1 4.41Å; F64-V324 HydrophobicContact CZ-CG2 3.6Å; Y150-V324 HydrophobicContact CD1-CB 3.52Å; Y150-V324 HydrophobicContact CD1-CG1 3.38Å; Y150-V324 HydrophobicContact CD1-CG2 3.99Å; Y150-V324 HydrophobicContact CD2-CG1 3.95Å; Y150-V324 HydrophobicContact CE1-CB 3.86Å; Y150-V324 HydrophobicContact CE1-CG1 3.58Å; Y150-V324 HydrophobicContact CE1-CG2 3.86Å; Y150-V324 HydrophobicContact CE2-CG1 4.13Å; Y150-V324 HydrophobicContact CG-CB 4.08Å; Y150-V324 HydrophobicContact CG-CG1 3.56Å; I320-V324 HydrophobicContact CG2-CG2 4.21Å; I320-V324 WeakPolarHBondContact O-CG2 3.35Å; I320-V324 PolarHBondContact O-N 2.9Å; P321-V324 PolarHBondContact O-N 3.49Å; I322-V324 VanDerWaalsContact C-N 3.32Å; I322-V324 PolarHBondContact O-N 2.93Å; V324-L326 PolarHBondContact O-N 3.28Å; V324-S327 VanDerWaalsContact O-CB 3.23Å; V324-S327 WeakPolarHBondContact O-CB 3.23Å; V324-S327 PolarHBondContact O-N 2.88Å; V324-C328 PolarHBondContact O-N 2.83Å; V324-C328 PolarHBondContact O-SG 2.78Å
325	A	89.7	Confident	86.3	Confident	4 Å²	4	38 Å²	38	3%	0.033	20%	0.195	C	C	.	.	H	α-helix	trans	-61.1	-45.4	175.5	0	0	0	0	0	111.5	F147 I151 P321 I322 S327 C328 F329	F147-A325 HydrophobicContact CD2-CB 3.99Å; F147-A325 WeakPolarHBondContact CD2-O 3.48Å; F147-A325 HydrophobicContact CE2-CB 4.12Å; I151-A325 HydrophobicContact CD1-CB 3.9Å; I151-A325 HydrophobicContact CG1-CB 3.45Å; I151-A325 VanDerWaalsContact CG1-CB 3.45Å; P321-A325 WeakPolarHBondContact O-CB 3.47Å; P321-A325 PolarHBondContact O-N 3.49Å; I322-A325 PolarHBondContact O-N 3.49Å; A325-S327 VanDerWaalsContact C-N 3.28Å; A325-S327 PolarHBondContact O-N 3.46Å; A325-C328 PolarHBondContact O-N 2.79Å; A325-F329 WeakPolarHBondContact O-CB 3.4Å; A325-F329 PolarHBondContact O-N 3.43Å
326	L	86.6	Confident	86.6	Confident	61 Å²	61	30 Å²	30	32%	0.319	16%	0.155	S	C	.	.	H	α-helix	trans	-62.1	-36.7	174.9	-67.1	177.2	0	0	0	112	F195 I322 V324 F329 G330	F195-L326 HydrophobicContact CD1-CB 4.04Å; F195-L326 HydrophobicContact CD1-CD1 4.32Å; F195-L326 HydrophobicContact CD1-CD2 4.31Å; F195-L326 HydrophobicContact CD1-CG 4.45Å; F195-L326 HydrophobicContact CE1-CB 4.35Å; F195-L326 HydrophobicContact CE1-CD1 4.15Å; F195-L326 HydrophobicContact CE1-CD2 3.75Å; F195-L326 HydrophobicContact CE1-CG 4.3Å; F195-L326 HydrophobicContact CE2-CD2 4.22Å; F195-L326 HydrophobicContact CG-CB 4.22Å; F195-L326 HydrophobicContact CZ-CD2 3.71Å; I322-L326 HydrophobicContact CG2-CD1 4.01Å; I322-L326 HydrophobicContact CG2-CG 4.32Å; I322-L326 WeakPolarHBondContact O-CB 3.27Å; I322-L326 VanDerWaalsContact O-CG 3.27Å; I322-L326 WeakPolarHBondContact O-CG 3.49Å; I322-L326 PolarHBondContact O-N 3.43Å; V324-L326 PolarHBondContact O-N 3.28Å; L326-F329 PolarHBondContact O-N 3.17Å; L326-G330 PolarHBondContact O-N 3.48Å
327	S	86.4	Confident	86.4	Confident	2 Å²	2	26.1 Å²	26.1	1%	0.014	14%	0.138	C	C	.	.	H	α-helix	trans	-59.6	-50	172.6	-173.9	0	0	0	0	111.8	K199 A323 V324 A325 F329 G330 G331	K199-S327 WeakPolarHBondContact CB-OG 3.11Å; K199-S327 WeakPolarHBondContact CD-OG 3.42Å; A323-S327 WeakPolarHBondContact O-CB 3.39Å; A323-S327 PolarHBondContact O-N 2.79Å; V324-S327 VanDerWaalsContact O-CB 3.23Å; V324-S327 WeakPolarHBondContact O-CB 3.23Å; V324-S327 PolarHBondContact O-N 2.88Å; A325-S327 VanDerWaalsContact C-N 3.28Å; A325-S327 PolarHBondContact O-N 3.46Å; S327-F329 VanDerWaalsContact C-N 3.35Å; S327-F329 PolarHBondContact O-N 2.98Å; S327-G330 PolarHBondContact O-N 3.32Å; S327-G331 PolarHBondContact O-N 3.28Å
328	C	89	Confident	86.1	Confident	0 Å²	0	27.6 Å²	27.6	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-64.6	-40.3	179.2	-61.9	0	0	0	0	111.3	I143 F147 V324 A325 G330 G331 L332	I143-C328 HydrophobicContact CG2-CB 3.93Å; I143-C328 WeakPolarHBondContact CG2-O 3.33Å; F147-C328 HydrophobicContact CB-CB 3.69Å; F147-C328 HydrophobicContact CD2-CB 4.45Å; V324-C328 PolarHBondContact O-N 2.83Å; V324-C328 PolarHBondContact O-SG 2.78Å; A325-C328 PolarHBondContact O-N 2.79Å; C328-G330 PolarHBondContact O-N 2.99Å; C328-G331 PolarHBondContact O-N 2.97Å; C328-L332 VanDerWaalsContact O-CB 3.26Å; C328-L332 WeakPolarHBondContact O-CB 3.35Å; C328-L332 PolarHBondContact O-N 3.2Å
329	F	88.1	Confident	86.1	Confident	41 Å²	41	20.1 Å²	20.1	18%	0.18	12%	0.123	C	C	.	.	H	α-helix	trans	-60.9	-45.3	176.1	-168.7	-86.7	0	0	0	111.8	F147 L176 L177 V191 F195 A325 L326 S327 N333	F147-F329 HydrophobicContact CD2-CB 4.31Å; F147-F329 HydrophobicContact CE2-CB 4.22Å; F147-F329 HydrophobicContact CE2-CD2 4.04Å; F147-F329 HydrophobicContact CZ-CD2 4.37Å; L176-F329 HydrophobicContact CD2-CE2 4.35Å; L177-F329 HydrophobicContact CD1-CD2 4.12Å; L177-F329 HydrophobicContact CD1-CE2 4.11Å; L177-F329 HydrophobicContact CD1-CG 4.33Å; L177-F329 HydrophobicContact CD1-CZ 4.33Å; L177-F329 HydrophobicContact CD2-CD1 4.07Å; L177-F329 HydrophobicContact CD2-CD2 4.5Å; L177-F329 HydrophobicContact CD2-CE1 3.39Å; L177-F329 HydrophobicContact CD2-CE2 3.88Å; L177-F329 HydrophobicContact CD2-CZ 3.28Å; L177-F329 HydrophobicContact CG-CD2 4.35Å; L177-F329 HydrophobicContact CG-CE1 4.24Å; L177-F329 HydrophobicContact CG-CE2 3.83Å; L177-F329 HydrophobicContact CG-CZ 3.78Å; V191-F329 HydrophobicContact CG1-CE1 4.26Å; F195-F329 HydrophobicContact CD2-CD1 4.34Å; F195-F329 AromaticContact CE2-CD1 3.81Å; F195-F329 HydrophobicContact CE2-CD1 3.81Å; F195-F329 HydrophobicContact CE2-CE1 4.36Å; A325-F329 WeakPolarHBondContact O-CB 3.4Å; A325-F329 PolarHBondContact O-N 3.43Å; L326-F329 PolarHBondContact O-N 3.17Å; S327-F329 VanDerWaalsContact C-N 3.35Å; S327-F329 PolarHBondContact O-N 2.98Å; F329-N333 WeakPolarHBondContact O-CB 3.2Å; F329-N333 PolarHBondContact O-N 2.94Å; F329-N333 VanDerWaalsContact O-N 3.08Å
330	G	82.9	Confident	85.8	Confident	7 Å²	7	18.2 Å²	18.2	7%	0.072	11%	0.111	C	C	.	.	H	α-helix	trans	-64.4	-43.6	175	0	0	0	0	0	113.1	L326 S327 C328 N333 A334	L326-G330 PolarHBondContact O-N 3.48Å; S327-G330 PolarHBondContact O-N 3.32Å; C328-G330 PolarHBondContact O-N 2.99Å; G330-N333 PolarHBondContact O-N 3.33Å; G330-A334 WeakPolarHBondContact O-CB 3.19Å; G330-A334 PolarHBondContact O-N 3.09Å
331	G	83.4	Confident	85.1	Confident	19 Å²	19	22.6 Å²	22.6	20%	0.196	13%	0.127	C	C	.	.	H	α-helix	trans	-64.6	-40.6	177.4	0	0	0	0	0	113	S327 C328 A334 S335	S327-G331 PolarHBondContact O-N 3.28Å; C328-G331 PolarHBondContact O-N 2.97Å; G331-A334 WeakPolarHBondContact O-CB 3.36Å; G331-A334 PolarHBondContact O-N 3.31Å; G331-S335 PolarHBondContact O-N 2.76Å
332	L	88.9	Confident	84.8	Confident	0 Å²	0	22.7 Å²	22.7	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-63.8	-44	176.1	-178.7	54.1	0	0	0	111	Q140 I143 A144 I174 L177 C328 A334 S335 I336	Q140-L332 HydrophobicContact CB-CD1 3.63Å; Q140-L332 HydrophobicContact CG-CD1 3.89Å; I143-L332 HydrophobicContact CG2-CB 3.82Å; A144-L332 HydrophobicContact CB-CD2 3.94Å; I174-L332 HydrophobicContact CG1-CD1 4.48Å; I174-L332 HydrophobicContact CG1-CD2 3.92Å; L177-L332 HydrophobicContact CD1-CB 3.79Å; L177-L332 HydrophobicContact CD1-CD2 3.67Å; L177-L332 HydrophobicContact CD1-CG 3.6Å; C328-L332 VanDerWaalsContact O-CB 3.26Å; C328-L332 WeakPolarHBondContact O-CB 3.35Å; C328-L332 PolarHBondContact O-N 3.2Å; L332-A334 VanDerWaalsContact C-N 3.34Å; L332-A334 PolarHBondContact O-N 3.31Å; L332-S335 PolarHBondContact O-N 3.38Å; L332-I336 HydrophobicContact CD1-CD1 4.1Å; L332-I336 HydrophobicContact CD1-CG1 4.32Å; L332-I336 HydrophobicContact CG-CD1 4.04Å; L332-I336 VanDerWaalsContact O-CG1 3.29Å; L332-I336 WeakPolarHBondContact O-CG1 3.26Å; L332-I336 PolarHBondContact O-N 3Å
333	N	86.1	Confident	84.6	Confident	5 Å²	5	18.7 Å²	18.7	3%	0.027	11%	0.107	C	C	.	.	H	α-helix	trans	-60.8	-43.1	175	-173.5	76.1	0	0	0	112.1	L177 N181 G188 F329 G330 I336 F337	L177-N333 HydrophobicContact CD1-CB 4.33Å; L177-N333 HydrophobicContact CD2-CB 3.96Å; N181-N333 PolarHBondContact ND2-OD1 3.43Å; G188-N333 PolarHBondContact O-ND2 3.36Å; G188-N333 VanDerWaalsContact O-ND2 3.15Å; F329-N333 WeakPolarHBondContact O-CB 3.2Å; F329-N333 PolarHBondContact O-N 2.94Å; F329-N333 VanDerWaalsContact O-N 3.08Å; G330-N333 PolarHBondContact O-N 3.33Å; N333-I336 PolarHBondContact O-N 3.37Å; N333-F337 WeakPolarHBondContact O-CB 3.38Å; N333-F337 PolarHBondContact O-N 3.18Å
334	A	80.1	Confident	84	Confident	16 Å²	16	20.5 Å²	20.5	13%	0.132	11%	0.112	C	C	.	.	H	α-helix	trans	-61.3	-44.5	177.1	0	0	0	0	0	112.1	G330 G331 L332 F337 A338	G330-A334 WeakPolarHBondContact O-CB 3.19Å; G330-A334 PolarHBondContact O-N 3.09Å; G331-A334 WeakPolarHBondContact O-CB 3.36Å; G331-A334 PolarHBondContact O-N 3.31Å; L332-A334 VanDerWaalsContact C-N 3.34Å; L332-A334 PolarHBondContact O-N 3.31Å; A334-F337 PolarHBondContact O-N 3.41Å; A334-A338 WeakPolarHBondContact O-CB 2.96Å; A334-A338 PolarHBondContact O-N 2.96Å
335	S	85.1	Confident	83.5	Confident	15 Å²	15	21.4 Å²	21.4	11%	0.105	12%	0.117	C	C	.	.	H	α-helix	trans	-67	-41.7	178.1	176.9	0	0	0	0	112.2	Q140 G331 L332 F337 A338 S339	Q140-S335 WeakPolarHBondContact CG-OG 3.41Å; Q140-S335 PolarHBondContact NE2-OG 3.31Å; G331-S335 PolarHBondContact O-N 2.76Å; L332-S335 PolarHBondContact O-N 3.38Å; S335-F337 VanDerWaalsContact C-N 3.28Å; S335-F337 PolarHBondContact O-N 3.41Å; S335-A338 PolarHBondContact O-N 3.21Å; S335-S339 WeakPolarHBondContact O-CB 3.33Å; S335-S339 PolarHBondContact O-N 3.46Å; S335-S339 PolarHBondContact O-OG 2.95Å
336	I	87.6	Confident	83.1	Confident	0 Å²	0	21.2 Å²	21.2	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-58.5	-43.8	173.9	-70.6	167.6	0	0	0	110.2	L177 N181 L332 N333 S339 S340 L370	L177-I336 HydrophobicContact CB-CD1 3.84Å; N181-I336 HydrophobicContact CB-CG2 4.41Å; L332-I336 HydrophobicContact CD1-CD1 4.1Å; L332-I336 HydrophobicContact CD1-CG1 4.32Å; L332-I336 HydrophobicContact CG-CD1 4.04Å; L332-I336 VanDerWaalsContact O-CG1 3.29Å; L332-I336 WeakPolarHBondContact O-CG1 3.26Å; L332-I336 PolarHBondContact O-N 3Å; N333-I336 PolarHBondContact O-N 3.37Å; I336-S339 PolarHBondContact O-OG 3.39Å; I336-S340 PolarHBondContact O-N 2.8Å; I336-L370 HydrophobicContact CG2-CD2 3.49Å; I336-L370 VanDerWaalsContact CG2-CD2 3.49Å
337	F	79.3	Confident	82.8	Confident	52 Å²	52	18.5 Å²	18.5	23%	0.228	10%	0.102	C	C	.	.	H	α-helix	trans	-65.9	-44.1	177.2	-173.4	-103.2	0	0	0	112.6	V185 N333 A334 S335 S340 R341	V185-F337 HydrophobicContact CG1-CD2 4.44Å; V185-F337 HydrophobicContact CG1-CE2 3.73Å; N333-F337 WeakPolarHBondContact O-CB 3.38Å; N333-F337 PolarHBondContact O-N 3.18Å; A334-F337 PolarHBondContact O-N 3.41Å; S335-F337 VanDerWaalsContact C-N 3.28Å; S335-F337 PolarHBondContact O-N 3.41Å; F337-S340 PolarHBondContact O-N 3.41Å; F337-S340 PolarHBondContact O-OG 3.37Å; F337-R341 PolarHBondContact O-N 3.2Å
338	A	78.4	Confident	82.3	Confident	41 Å²	41	24.4 Å²	24.4	34%	0.339	12%	0.124	S	C	.	.	H	α-helix	trans	-61.7	-45.3	178	0	0	0	0	0	112.2	A334 S335 S340 R341 L342	A334-A338 WeakPolarHBondContact O-CB 2.96Å; A334-A338 PolarHBondContact O-N 2.96Å; S335-A338 PolarHBondContact O-N 3.21Å; A338-S340 VanDerWaalsContact C-N 3.28Å; A338-S340 PolarHBondContact O-N 3.47Å; A338-R341 WeakPolarHBondContact O-CB 3.48Å; A338-R341 PolarHBondContact O-N 3.29Å; A338-R341 VanDerWaalsContact O-N 3.14Å; A338-L342 PolarHBondContact O-N 2.96Å
339	S	83.8	Confident	82	Confident	0 Å²	0	28.2 Å²	28.2	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-58.3	-40.8	177.4	70.5	0	0	0	0	111.7	S335 I336 R341 L342 F343 N373	S335-S339 WeakPolarHBondContact O-CB 3.33Å; S335-S339 PolarHBondContact O-N 3.46Å; S335-S339 PolarHBondContact O-OG 2.95Å; I336-S339 PolarHBondContact O-OG 3.39Å; S339-R341 VanDerWaalsContact C-N 3.3Å; S339-R341 PolarHBondContact O-N 3.23Å; S339-L342 WeakPolarHBondContact O-CB 3.22Å; S339-L342 PolarHBondContact O-N 2.91Å; S339-F343 WeakPolarHBondContact O-CD2 3.24Å; S339-F343 PolarHBondContact O-N 2.91Å; S339-N373 PolarHBondContact OG-ND2 3.01Å
340	S	81	Confident	81.6	Confident	7 Å²	7	28.5 Å²	28.5	5%	0.049	16%	0.156	C	C	.	.	H	α-helix	trans	-59.1	-38.1	178.1	78.7	0	0	0	0	113.2	I336 F337 A338 L342 F343 F344	I336-S340 PolarHBondContact O-N 2.8Å; F337-S340 PolarHBondContact O-N 3.41Å; F337-S340 PolarHBondContact O-OG 3.37Å; A338-S340 VanDerWaalsContact C-N 3.28Å; A338-S340 PolarHBondContact O-N 3.47Å; S340-L342 VanDerWaalsContact C-N 3.34Å; S340-F343 PolarHBondContact O-N 3.06Å; S340-F344 VanDerWaalsContact O-CD2 3.24Å; S340-F344 WeakPolarHBondContact O-CD2 3.31Å; S340-F344 PolarHBondContact O-N 3.26Å
341	R	76.6	Confident	81.7	Confident	97 Å²	97	29 Å²	29	37%	0.366	16%	0.156	S	C	.	.	H	α-helix	trans	-66.8	-36.4	175.7	-66.8	-178	175	-153	-3.7	111.8	E259 F337 A338 S339 F343 F344 V345	E259-R341 IonicContact OE1-CZ 2.89Å; E259-R341 IonicContact OE1-NH1 2.87Å; E259-R341 PolarHBondContact OE1-NH1 2.84Å; E259-R341 IonicContact OE1-NH2 3.38Å; F337-R341 PolarHBondContact O-N 3.2Å; A338-R341 WeakPolarHBondContact O-CB 3.48Å; A338-R341 PolarHBondContact O-N 3.29Å; A338-R341 VanDerWaalsContact O-N 3.14Å; S339-R341 VanDerWaalsContact C-N 3.3Å; S339-R341 PolarHBondContact O-N 3.23Å; R341-F343 VanDerWaalsContact C-N 3.32Å; R341-F343 PolarHBondContact O-N 2.69Å; R341-F344 PolarHBondContact O-N 3.23Å; R341-V345 WeakPolarHBondContact O-CG2 2.98Å; R341-V345 PolarHBondContact O-N 3.39Å
342	L	81.8	Confident	81.8	Confident	7 Å²	7	28.8 Å²	28.8	4%	0.037	15%	0.15	C	C	.	.	H	α-helix	trans	-64.6	-36.9	178	-171.5	61.2	0	0	0	111.8	L128 L132 F255 A338 S339 S340 V345 G346	L128-L342 HydrophobicContact CD1-CD1 3.77Å; L128-L342 HydrophobicContact CD1-CD2 4.22Å; L128-L342 HydrophobicContact CD1-CG 3.66Å; L132-L342 HydrophobicContact CD2-CB 4.31Å; L132-L342 HydrophobicContact CD2-CD2 3.8Å; L132-L342 HydrophobicContact CD2-CG 4Å; F255-L342 HydrophobicContact CE1-CD1 4.46Å; A338-L342 PolarHBondContact O-N 2.96Å; S339-L342 WeakPolarHBondContact O-CB 3.22Å; S339-L342 PolarHBondContact O-N 2.91Å; S340-L342 VanDerWaalsContact C-N 3.34Å; L342-V345 PolarHBondContact O-N 3.11Å; L342-G346 PolarHBondContact O-N 3.28Å
343	F	84.7	Confident	81.4	Confident	1 Å²	1	31.5 Å²	31.5	0%	0.004	17%	0.168	C	C	.	.	H	α-helix	trans	-61.9	-42.9	172.6	-73.1	-81.4	0	0	0	112.4	L132 S339 S340 R341 G346 S347 L352 L356 A369 F372 N373	L132-F343 HydrophobicContact CB-CE1 4.27Å; L132-F343 HydrophobicContact CB-CZ 4.17Å; L132-F343 HydrophobicContact CD1-CD1 3.92Å; L132-F343 HydrophobicContact CD1-CE1 3.71Å; L132-F343 HydrophobicContact CD1-CZ 4.31Å; L132-F343 HydrophobicContact CD2-CD1 4.08Å; L132-F343 HydrophobicContact CD2-CD2 4.02Å; L132-F343 HydrophobicContact CD2-CE1 3.79Å; L132-F343 HydrophobicContact CD2-CE2 3.7Å; L132-F343 HydrophobicContact CD2-CG 4.18Å; L132-F343 HydrophobicContact CD2-CZ 3.57Å; L132-F343 HydrophobicContact CG-CE1 4.11Å; L132-F343 HydrophobicContact CG-CZ 4.2Å; S339-F343 WeakPolarHBondContact O-CD2 3.24Å; S339-F343 PolarHBondContact O-N 2.91Å; S340-F343 PolarHBondContact O-N 3.06Å; R341-F343 VanDerWaalsContact C-N 3.32Å; R341-F343 PolarHBondContact O-N 2.69Å; F343-G346 PolarHBondContact O-N 3.22Å; F343-S347 PolarHBondContact O-N 2.96Å; F343-L352 HydrophobicContact CD1-CD1 4.13Å; F343-L356 HydrophobicContact CD1-CB 4.07Å; F343-L356 HydrophobicContact CD1-CD1 3.97Å; F343-L356 HydrophobicContact CD1-CG 4.42Å; F343-L356 HydrophobicContact CE1-CD1 4.13Å; F343-A369 HydrophobicContact CB-CB 3.86Å; F343-A369 HydrophobicContact CD1-CB 4.43Å; F343-A369 HydrophobicContact CD2-CB 3.79Å; F343-A369 HydrophobicContact CE2-CB 4.49Å; F343-A369 HydrophobicContact CG-CB 3.79Å; F343-F372 AromaticContact CE1-CD1 3.63Å; F343-F372 HydrophobicContact CE1-CD1 3.63Å; F343-F372 AromaticContact CE1-CE1 3.97Å; F343-F372 HydrophobicContact CE1-CE1 3.97Å; F343-F372 HydrophobicContact CE1-CG 4.49Å; F343-F372 AromaticContact CZ-CD1 3.48Å; F343-F372 HydrophobicContact CZ-CD1 3.48Å; F343-F372 VanDerWaalsContact CZ-CD1 3.48Å; F343-F372 AromaticContact CZ-CE1 3.94Å; F343-F372 HydrophobicContact CZ-CE1 3.94Å; F343-N373 HydrophobicContact CE2-CB 4.08Å; F343-N373 HydrophobicContact CZ-CB 4.42Å
344	F	76.3	Confident	81.1	Confident	54 Å²	54	34.8 Å²	34.8	24%	0.237	19%	0.186	C	C	.	.	H	α-helix	trans	-61.7	-48	176	-81	-73.2	0	0	0	112.8	S340 R341 G346 S347 R348 S357 I359 P366	S340-F344 VanDerWaalsContact O-CD2 3.24Å; S340-F344 WeakPolarHBondContact O-CD2 3.31Å; S340-F344 PolarHBondContact O-N 3.26Å; R341-F344 PolarHBondContact O-N 3.23Å; F344-G346 VanDerWaalsContact C-N 3.3Å; F344-G346 PolarHBondContact O-N 2.85Å; F344-S347 PolarHBondContact O-N 2.89Å; F344-R348 WeakPolarHBondContact O-CB 3.18Å; F344-R348 PolarHBondContact O-N 3.42Å; F344-S357 WeakPolarHBondContact CE1-O 3.42Å; F344-I359 HydrophobicContact CE1-CD1 3.57Å; F344-I359 HydrophobicContact CE1-CG1 3.62Å; F344-I359 HydrophobicContact CZ-CD1 3.47Å; F344-I359 VanDerWaalsContact CZ-CD1 3.47Å; F344-I359 HydrophobicContact CZ-CG1 3.53Å; F344-P366 HydrophobicContact CE2-CB 3.47Å; F344-P366 VanDerWaalsContact CE2-CB 3.47Å; F344-P366 HydrophobicContact CE2-CG 3.7Å; F344-P366 HydrophobicContact CZ-CB 3.6Å; F344-P366 HydrophobicContact CZ-CG 4.22Å
345	V	77.1	Confident	81.2	Confident	21 Å²	21	34.9 Å²	34.9	13%	0.127	18%	0.184	C	C	.	.	H	α-helix	trans	-62.1	-42.8	179.8	175.1	0	0	0	0	110.4	Y112 R341 L342 S347 R348 E349	Y112-V345 HydrophobicContact CD1-CG1 3.83Å; Y112-V345 HydrophobicContact CE1-CG1 3.75Å; R341-V345 WeakPolarHBondContact O-CG2 2.98Å; R341-V345 PolarHBondContact O-N 3.39Å; L342-V345 PolarHBondContact O-N 3.11Å; V345-S347 PolarHBondContact O-N 3.49Å; V345-R348 PolarHBondContact O-N 3.34Å; V345-E349 WeakPolarHBondContact O-CG 3.42Å; V345-E349 PolarHBondContact O-N 3.24Å
346	G	81.9	Confident	81.1	Confident	0 Å²	0	35.2 Å²	35.2	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-62.6	-38.9	177.5	0	0	0	0	0	114	L342 F343 F344 H351 L352	L342-G346 PolarHBondContact O-N 3.28Å; F343-G346 PolarHBondContact O-N 3.22Å; F344-G346 VanDerWaalsContact C-N 3.3Å; F344-G346 PolarHBondContact O-N 2.85Å; G346-H351 WeakPolarHBondContact O-CB 3.2Å; G346-H351 PolarHBondContact O-N 3.49Å; G346-L352 PolarHBondContact O-N 2.91Å
347	S	80.3	Confident	80.8	Confident	3 Å²	3	35.5 Å²	35.5	2%	0.021	19%	0.186	C	C	.	.	H	α-helix	trans	-74.4	-37.1	177.5	174.5	0	0	0	0	112.5	F343 F344 V345 E349 G350 S357	F343-S347 PolarHBondContact O-N 2.96Å; F344-S347 PolarHBondContact O-N 2.89Å; V345-S347 PolarHBondContact O-N 3.49Å; S347-E349 PolarHBondContact O-N 3.28Å; S347-G350 PolarHBondContact O-N 3.48Å; S347-S357 VanDerWaalsContact CB-CB 3.49Å; S347-S357 VanDerWaalsContact OG-CB 3.25Å; S347-S357 WeakPolarHBondContact OG-CB 3.17Å; S347-S357 PolarHBondContact OG-OG 3.4Å
348	R	76.8	Confident	81	Confident	126 Å²	126	33.2 Å²	33.2	48%	0.475	18%	0.176	S	C	.	.	H	α-helix	trans	-59.5	-34.8	176.9	-171.1	179	70.1	-175.4	0.7	112.5	F344 V345 G350 L502	F344-R348 WeakPolarHBondContact O-CB 3.18Å; F344-R348 PolarHBondContact O-N 3.42Å; V345-R348 PolarHBondContact O-N 3.34Å; R348-G350 PolarHBondContact O-N 3.35Å; R348-L502 HydrophobicContact CB-CD2 4.43Å; R348-L502 HydrophobicContact CG-CD2 4.1Å
349	E	81.6	Confident	81.4	Confident	81 Å²	81	32.7 Å²	32.7	38%	0.379	17%	0.168	S	C	.	.	T	Hydrogen-bonded Turn	trans	-83.3	8.4	176.6	-59.4	-68.3	152.3	0	0	113.1	Y112 L116 V345 S347 H351	Y112-E349 HydrophobicContact CE1-CG 4.01Å; Y112-E349 VanDerWaalsContact OH-CB 3.24Å; Y112-E349 WeakPolarHBondContact OH-CB 3.44Å; Y112-E349 WeakPolarHBondContact OH-CG 3.41Å; L116-E349 HydrophobicContact CD2-CG 4.31Å; V345-E349 WeakPolarHBondContact O-CG 3.42Å; V345-E349 PolarHBondContact O-N 3.24Å; S347-E349 PolarHBondContact O-N 3.28Å; E349-H351 PolarHBondContact O-N 3.41Å
350	G	80.7	Confident	81.5	Confident	46 Å²	46	33.7 Å²	33.7	47%	0.474	17%	0.172	S	C	.	.	T	Hydrogen-bonded Turn	trans	69.6	10.1	-179.8	0	0	0	0	0	114.8	S347 R348	S347-G350 PolarHBondContact O-N 3.48Å; R348-G350 PolarHBondContact O-N 3.35Å
351	H	84.3	Confident	81.6	Confident	17 Å²	17	37.8 Å²	37.8	8%	0.079	19%	0.193	C	C	.	.	S	Bend	trans	-85.6	-21.2	-178.3	-76.8	173.7	0	0	0	113.5	Y112 G121 F125 L128 G346 E349	Y112-H351 AromaticContact CE2-ND1 3.74Å; Y112-H351 AromaticContact CZ-ND1 3.7Å; Y112-H351 PolarHBondContact OH-CE1 3.17Å; Y112-H351 PolarHBondContact OH-ND1 3.49Å; G121-H351 PolarHBondContact O-CE1 3.24Å; F125-H351 HydrophobicContact CD2-CB 3.99Å; F125-H351 WeakPolarHBondContact CD2-O 3.47Å; F125-H351 WeakPolarHBondContact CE2-O 3.49Å; L128-H351 HydrophobicContact CD2-CB 4.02Å; G346-H351 WeakPolarHBondContact O-CB 3.2Å; G346-H351 PolarHBondContact O-N 3.49Å; E349-H351 PolarHBondContact O-N 3.41Å
352	L	84.8	Confident	82	Confident	15 Å²	15	40.6 Å²	40.6	8%	0.079	21%	0.21	C	C	.	.	S	Bend	trans	-119.3	151.6	176.2	-66.4	172.2	0	0	0	110.9	L128 L132 F343 G346 D354 L356	L128-L352 HydrophobicContact CD2-CD1 3.95Å; L128-L352 HydrophobicContact CD2-CD2 4.23Å; L128-L352 HydrophobicContact CD2-CG 3.81Å; L128-L352 HydrophobicContact CG-CD1 4.47Å; L132-L352 HydrophobicContact CD1-CD1 3.7Å; L132-L352 HydrophobicContact CD1-CD2 3.94Å; L132-L352 HydrophobicContact CD1-CG 4.44Å; F343-L352 HydrophobicContact CD1-CD1 4.13Å; G346-L352 PolarHBondContact O-N 2.91Å; L352-D354 PolarHBondContact O-N 3.18Å; L352-L356 HydrophobicContact CD2-CD1 4.49Å
353	P	81.9	Confident	81.8	Confident	58 Å²	58	45.8 Å²	45.8	38%	0.377	23%	0.229	S	C	.	.			trans	-57.8	137.9	171.2	-21.1	32	0	0	0	111.6	L355 L356 L484	P353-L355 PolarHBondContact O-N 2.97Å; P353-L356 PolarHBondContact O-N 2.99Å; P353-L484 HydrophobicContact CB-CD1 4.43Å
354	D	79.8	Confident	81.7	Confident	74 Å²	74	53.4 Å²	53.4	40%	0.396	26%	0.262	S	S	.	.	G	3₁₀ helix	trans	-50.1	-25.9	176.6	-69	-12.1	0	0	0	114.3	L352 L356 S357 M358 L499	L352-D354 PolarHBondContact O-N 3.18Å; D354-L356 PolarHBondContact O-N 3.11Å; D354-S357 PolarHBondContact O-N 3.05Å; D354-S357 VanDerWaalsContact O-N 3.17Å; D354-S357 PolarHBondContact O-OG 2.9Å; D354-M358 VanDerWaalsContact O-CG 3.29Å; D354-M358 WeakPolarHBondContact O-CG 3.27Å; D354-M358 PolarHBondContact O-N 2.7Å; D354-L499 HydrophobicContact CB-CD1 3.62Å; D354-L499 HydrophobicContact CB-CD2 4.38Å; D354-L499 WeakPolarHBondContact O-CD1 3.37Å
355	L	82.1	Confident	82	Confident	17 Å²	17	50.8 Å²	50.8	9%	0.089	25%	0.251	C	S	.	.	G	3₁₀ helix	trans	-51.5	-38.7	172.9	177.6	60.2	0	0	0	113.4	P353 S357 M358 P368 I487 T488 I491	P353-L355 PolarHBondContact O-N 2.97Å; L355-S357 VanDerWaalsContact C-N 3.32Å; L355-M358 HydrophobicContact CD1-SD 4.05Å; L355-M358 WeakPolarHBondContact O-CG 3.47Å; L355-P368 HydrophobicContact CD1-CB 4.49Å; L355-P368 WeakPolarHBondContact O-CB 3.31Å; L355-I487 HydrophobicContact CD2-CG2 3.93Å; L355-T488 HydrophobicContact CD1-CG2 4.41Å; L355-I491 HydrophobicContact CD1-CB 3.72Å; L355-I491 HydrophobicContact CD1-CD1 3.74Å; L355-I491 HydrophobicContact CD1-CG1 4.32Å; L355-I491 HydrophobicContact CD1-CG2 3.59Å; L355-I491 HydrophobicContact CD2-CD1 3.61Å; L355-I491 HydrophobicContact CG-CD1 4.15Å
356	L	82.8	Confident	82.5	Confident	23 Å²	23	50.3 Å²	50.3	12%	0.12	25%	0.248	C	C	.	.	G	3₁₀ helix	trans	-83.6	-7.5	-174.1	-63.4	174.6	0	0	0	113.1	F343 L352 P353 D354 F372	F343-L356 HydrophobicContact CD1-CB 4.07Å; F343-L356 HydrophobicContact CD1-CD1 3.97Å; F343-L356 HydrophobicContact CD1-CG 4.42Å; F343-L356 HydrophobicContact CE1-CD1 4.13Å; L352-L356 HydrophobicContact CD2-CD1 4.49Å; P353-L356 PolarHBondContact O-N 2.99Å; D354-L356 PolarHBondContact O-N 3.11Å; L356-F372 HydrophobicContact CD2-CB 4.15Å; L356-F372 HydrophobicContact CD2-CG 4.37Å
357	S	80.9	Confident	82.8	Confident	5 Å²	5	51.3 Å²	51.3	4%	0.035	25%	0.253	C	S	.	.	G	3₁₀ helix	trans	-105.1	6	172.4	55.2	0	0	0	0	113.5	F344 S347 D354 L355 L499	F344-S357 WeakPolarHBondContact CE1-O 3.42Å; S347-S357 VanDerWaalsContact CB-CB 3.49Å; S347-S357 VanDerWaalsContact OG-CB 3.25Å; S347-S357 WeakPolarHBondContact OG-CB 3.17Å; S347-S357 PolarHBondContact OG-OG 3.4Å; D354-S357 PolarHBondContact O-N 3.05Å; D354-S357 VanDerWaalsContact O-N 3.17Å; D354-S357 PolarHBondContact O-OG 2.9Å; L355-S357 VanDerWaalsContact C-N 3.32Å; S357-L499 WeakPolarHBondContact OG-CD1 3.43Å
358	M	84.4	Confident	83.3	Confident	4 Å²	4	51.5 Å²	51.5	2%	0.02	26%	0.255	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-70.8	143.1	179.5	-58.1	-173	169.3	0	0	112.2	D354 L355 P366 P368 T488 Q492 C497 V498 L499	D354-M358 VanDerWaalsContact O-CG 3.29Å; D354-M358 WeakPolarHBondContact O-CG 3.27Å; D354-M358 PolarHBondContact O-N 2.7Å; L355-M358 HydrophobicContact CD1-SD 4.05Å; L355-M358 WeakPolarHBondContact O-CG 3.47Å; M358-P366 WeakPolarHBondContact O-CA 3.28Å; M358-P368 HydrophobicContact CB-CG 4.32Å; M358-T488 HydrophobicContact CE-CG2 3.3Å; M358-T488 HydrophobicContact SD-CG2 4.3Å; M358-Q492 HydrophobicContact CE-CG 3.99Å; M358-Q492 VanDerWaalsContact CE-NE2 3.31Å; M358-Q492 HydrophobicContact SD-CG 3.49Å; M358-Q492 WeakPolarHBondContact SD-CG 3.43Å; M358-C497 HydrophobicContact CB-CB 3.73Å; M358-V498 CarbonylContact C-O 3.54Å; M358-V498 WeakPolarHBondContact CA-O 3.18Å; M358-L499 HydrophobicContact CE-CD1 4.41Å; M358-L499 HydrophobicContact CG-CD1 4.14Å
359	I	85.2	Confident	83.9	Confident	31 Å²	31	45.5 Å²	45.5	16%	0.159	23%	0.232	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-117.5	138.3	-178.4	-55.3	-164.3	0	0	0	110	F344 F364 C497 V498 T500	F344-I359 HydrophobicContact CE1-CD1 3.57Å; F344-I359 HydrophobicContact CE1-CG1 3.62Å; F344-I359 HydrophobicContact CZ-CD1 3.47Å; F344-I359 VanDerWaalsContact CZ-CD1 3.47Å; F344-I359 HydrophobicContact CZ-CG1 3.53Å; I359-F364 HydrophobicContact CG2-CB 4.34Å; I359-C497 CarbonylContact O-C 3.47Å; I359-C497 VanDerWaalsContact O-CA 3.24Å; I359-C497 WeakPolarHBondContact O-CA 3.48Å; I359-V498 PolarHBondContact N-O 2.99Å; I359-V498 PolarHBondContact O-N 3.46Å; I359-T500 HydrophobicContact CB-CG2 4.44Å; I359-T500 HydrophobicContact CD1-CG2 3.22Å; I359-T500 HydrophobicContact CG1-CG2 3.68Å
360	H	86.4	Confident	84.4	Confident	21 Å²	21	41.8 Å²	41.8	10%	0.097	22%	0.215	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-64.9	133.8	172.2	-175.3	-64.4	0	0	0	111.9	E362 R363 F364 T365 I367 C495	H360-E362 PolarHBondContact ND1-N 3.39Å; H360-E362 PolarHBondContact O-N 3.27Å; H360-R363 HydrophobicContact CB-CB 4.31Å; H360-R363 PolarHBondContact ND1-N 3.46Å; H360-F364 WeakPolarHBondContact O-CA 3.33Å; H360-F364 PolarHBondContact O-N 3.21Å; H360-T365 PolarHBondContact N-O 3.11Å; H360-I367 HydrophobicContact CB-CD1 3.79Å; H360-I367 HydrophobicContact CB-CG1 4.23Å; H360-I367 VanDerWaalsContact CD2-CD1 3.47Å; H360-I367 WeakPolarHBondContact CD2-CD1 3.49Å; H360-C495 PolarHBondContact CD2-O 2.95Å
361	I	83.9	Confident	84.9	Confident	93 Å²	93	43.5 Å²	43.5	48%	0.477	21%	0.212	S	C	.	.	T	Hydrogen-bonded Turn	trans	-57.8	-49.6	-172.2	-61.9	161.7	0	0	0	113.1	F496 V498	I361-F496 WeakPolarHBondContact CG1-O 3.44Å; I361-F496 PolarHBondContact N-O 3.36Å; I361-F496 VanDerWaalsContact N-O 3.15Å; I361-V498 HydrophobicContact CD1-CG1 3.96Å; I361-V498 HydrophobicContact CG1-CG1 3.81Å; I361-V498 HydrophobicContact CG1-CG2 3.95Å
362	E	83.4	Confident	85.3	Confident	155 Å²	155	45.7 Å²	45.7	72%	0.724	22%	0.222	S	C	*	.	T	Hydrogen-bonded Turn	trans	-86.7	-32.7	-176.3	-57.6	-177.1	161.9	0	0	114.4	H360 F364	H360-E362 PolarHBondContact ND1-N 3.39Å; H360-E362 PolarHBondContact O-N 3.27Å; E362-F364 WeakPolarHBondContact O-CD2 3.42Å
363	R	79.1	Confident	85.7	Confident	117 Å²	117	45 Å²	45	44%	0.442	22%	0.218	S	C	.	.	T	Hydrogen-bonded Turn	trans	-95.3	-18.2	-169.7	-59.5	177.5	-174.4	-87.5	-3.5	113.2	C182 A183 H360 T365	C182-R363 WeakPolarHBondContact O-CD 3.41Å; A183-R363 WeakPolarHBondContact O-CD 3.33Å; A183-R363 PolarHBondContact O-NH1 3.14Å; H360-R363 HydrophobicContact CB-CB 4.31Å; H360-R363 PolarHBondContact ND1-N 3.46Å; R363-T365 VanDerWaalsContact C-N 3.27Å; R363-T365 HydrophobicContact CB-CG2 3.97Å; R363-T365 WeakPolarHBondContact O-CG2 3.44Å; R363-T365 PolarHBondContact O-N 3.08Å
364	F	82.2	Confident	86.4	Confident	160 Å²	160	42.7 Å²	42.7	70%	0.702	20%	0.204	S	C	*	.			trans	57.2	38.8	-176.2	-56.1	-84.3	0	0	0	113.2	I359 H360 E362	I359-F364 HydrophobicContact CG2-CB 4.34Å; H360-F364 WeakPolarHBondContact O-CA 3.33Å; H360-F364 PolarHBondContact O-N 3.21Å; E362-F364 WeakPolarHBondContact O-CD2 3.42Å
365	T	83.1	Confident	87.2	Confident	0 Å²	0	42.8 Å²	42.8	0%	0	21%	0.207	C	C	.	.			trans	-119.2	141.9	-177	59.7	0	0	0	0	112.6	C182 V185 H360 R363 I367	C182-T365 PolarHBondContact O-OG1 2.92Å; C182-T365 VanDerWaalsContact O-OG1 3.11Å; V185-T365 HydrophobicContact CB-CG2 4.42Å; V185-T365 HydrophobicContact CG2-CG2 3.42Å; V185-T365 VanDerWaalsContact CG2-CG2 3.42Å; H360-T365 PolarHBondContact N-O 3.11Å; R363-T365 VanDerWaalsContact C-N 3.27Å; R363-T365 HydrophobicContact CB-CG2 3.97Å; R363-T365 WeakPolarHBondContact O-CG2 3.44Å; R363-T365 PolarHBondContact O-N 3.08Å; T365-I367 PolarHBondContact O-N 3.13Å
366	P	87.2	Confident	87.8	Confident	11 Å²	11	44 Å²	44	7%	0.071	21%	0.213	C	C	.	.			trans	-82.1	72.1	-179.8	34.5	-37.5	0	0	0	112.9	F344 M358 A369 L370	F344-P366 HydrophobicContact CE2-CB 3.47Å; F344-P366 VanDerWaalsContact CE2-CB 3.47Å; F344-P366 HydrophobicContact CE2-CG 3.7Å; F344-P366 HydrophobicContact CZ-CB 3.6Å; F344-P366 HydrophobicContact CZ-CG 4.22Å; M358-P366 WeakPolarHBondContact O-CA 3.28Å; P366-A369 HydrophobicContact CB-CB 4.25Å; P366-A369 PolarHBondContact O-N 3.45Å; P366-L370 HydrophobicContact CG-CD1 4.34Å; P366-L370 HydrophobicContact CG-CG 4.32Å; P366-L370 VanDerWaalsContact O-CG 3.3Å; P366-L370 WeakPolarHBondContact O-CG 3.47Å; P366-L370 PolarHBondContact O-N 2.81Å; P366-L370 VanDerWaalsContact O-N 3.13Å
367	I	89	Confident	88.4	Confident	20 Å²	20	43 Å²	43	10%	0.103	21%	0.207	C	C	.	.	H	α-helix	trans	-58	-46.6	-174	-60.1	-179.6	0	0	0	112.7	C182 H360 T365 A369 L370 L371 C495	C182-I367 HydrophobicContact CB-CG1 4.2Å; H360-I367 HydrophobicContact CB-CD1 3.79Å; H360-I367 HydrophobicContact CB-CG1 4.23Å; H360-I367 VanDerWaalsContact CD2-CD1 3.47Å; H360-I367 WeakPolarHBondContact CD2-CD1 3.49Å; T365-I367 PolarHBondContact O-N 3.13Å; I367-A369 PolarHBondContact O-N 3.22Å; I367-L370 PolarHBondContact O-N 3.04Å; I367-L371 HydrophobicContact CG2-CD1 3.78Å; I367-L371 HydrophobicContact CG2-CG 4.04Å; I367-L371 WeakPolarHBondContact O-CG 3.22Å; I367-L371 PolarHBondContact O-N 3.35Å; I367-C495 HydrophobicContact CG2-CB 4.27Å
368	P	89.9	Confident	89.2	Confident	8 Å²	8	45.5 Å²	45.5	5%	0.052	22%	0.22	C	C	.	.	H	α-helix	trans	-62.2	-41	-177.4	-25.6	37.4	0	0	0	113.5	L355 M358 L371 F372 I491	L355-P368 HydrophobicContact CD1-CB 4.49Å; L355-P368 WeakPolarHBondContact O-CB 3.31Å; M358-P368 HydrophobicContact CB-CG 4.32Å; P368-L371 PolarHBondContact O-N 3.4Å; P368-F372 WeakPolarHBondContact O-CB 3.32Å; P368-F372 PolarHBondContact O-N 2.57Å; P368-I491 HydrophobicContact CB-CG2 4.15Å; P368-I491 HydrophobicContact CG-CG2 3.7Å
369	A	89.3	Confident	89.7	Confident	0 Å²	0	49.4 Å²	49.4	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-62.8	-44.5	175.6	0	0	0	0	0	111.9	F343 P366 I367 L371 F372 N373	F343-A369 HydrophobicContact CB-CB 3.86Å; F343-A369 HydrophobicContact CD1-CB 4.43Å; F343-A369 HydrophobicContact CD2-CB 3.79Å; F343-A369 HydrophobicContact CE2-CB 4.49Å; F343-A369 HydrophobicContact CG-CB 3.79Å; P366-A369 HydrophobicContact CB-CB 4.25Å; P366-A369 PolarHBondContact O-N 3.45Å; I367-A369 PolarHBondContact O-N 3.22Å; A369-L371 PolarHBondContact O-N 2.7Å; A369-F372 PolarHBondContact O-N 3.24Å; A369-N373 WeakPolarHBondContact O-CB 3.27Å; A369-N373 PolarHBondContact O-N 2.85Å
370	L	91.1	Very high	90.2	Very high	3 Å²	3	49.4 Å²	49.4	2%	0.016	24%	0.238	C	C	.	.	H	α-helix	trans	-63.2	-40.9	178.5	-69.9	172	0	0	0	111.8	T178 N181 C182 I336 P366 I367 C374	T178-L370 HydrophobicContact CG2-CB 4.18Å; N181-L370 HydrophobicContact CB-CD1 4.02Å; N181-L370 HydrophobicContact CB-CD2 4.33Å; C182-L370 VanDerWaalsContact SG-CD1 3.6Å; I336-L370 HydrophobicContact CG2-CD2 3.49Å; I336-L370 VanDerWaalsContact CG2-CD2 3.49Å; P366-L370 HydrophobicContact CG-CD1 4.34Å; P366-L370 HydrophobicContact CG-CG 4.32Å; P366-L370 VanDerWaalsContact O-CG 3.3Å; P366-L370 WeakPolarHBondContact O-CG 3.47Å; P366-L370 PolarHBondContact O-N 2.81Å; P366-L370 VanDerWaalsContact O-N 3.13Å; I367-L370 PolarHBondContact O-N 3.04Å; L370-C374 WeakPolarHBondContact O-CB 3.28Å; L370-C374 PolarHBondContact O-N 3.31Å
371	L	92.8	Very high	90.6	Very high	81 Å²	81	49 Å²	49	42%	0.424	24%	0.237	S	C	.	.	H	α-helix	trans	-68	-41.4	176.8	-69.4	179.3	0	0	0	112.3	I367 P368 A369 C374 T375	I367-L371 HydrophobicContact CG2-CD1 3.78Å; I367-L371 HydrophobicContact CG2-CG 4.04Å; I367-L371 WeakPolarHBondContact O-CG 3.22Å; I367-L371 PolarHBondContact O-N 3.35Å; P368-L371 PolarHBondContact O-N 3.4Å; A369-L371 PolarHBondContact O-N 2.7Å; L371-C374 PolarHBondContact O-N 2.92Å; L371-T375 WeakPolarHBondContact O-CB 3.29Å; L371-T375 PolarHBondContact O-N 3.28Å; L371-T375 PolarHBondContact O-OG1 3.05Å
372	F	92.8	Very high	91	Very high	64 Å²	64	50.7 Å²	50.7	28%	0.281	25%	0.245	S	C	.	.	H	α-helix	trans	-61.3	-49.8	175.4	177.8	-89.2	0	0	0	111	L133 F343 L356 P368 A369 C374 T375 M376	L133-F372 HydrophobicContact CD2-CE1 4.26Å; L133-F372 HydrophobicContact CD2-CZ 3.79Å; F343-F372 AromaticContact CE1-CD1 3.63Å; F343-F372 HydrophobicContact CE1-CD1 3.63Å; F343-F372 AromaticContact CE1-CE1 3.97Å; F343-F372 HydrophobicContact CE1-CE1 3.97Å; F343-F372 HydrophobicContact CE1-CG 4.49Å; F343-F372 AromaticContact CZ-CD1 3.48Å; F343-F372 HydrophobicContact CZ-CD1 3.48Å; F343-F372 VanDerWaalsContact CZ-CD1 3.48Å; F343-F372 AromaticContact CZ-CE1 3.94Å; F343-F372 HydrophobicContact CZ-CE1 3.94Å; L356-F372 HydrophobicContact CD2-CB 4.15Å; L356-F372 HydrophobicContact CD2-CG 4.37Å; P368-F372 WeakPolarHBondContact O-CB 3.32Å; P368-F372 PolarHBondContact O-N 2.57Å; A369-F372 PolarHBondContact O-N 3.24Å; F372-C374 PolarHBondContact O-N 3.25Å; F372-T375 PolarHBondContact O-N 2.8Å; F372-M376 HydrophobicContact CD1-CG 4.29Å; F372-M376 HydrophobicContact CE1-CG 3.85Å; F372-M376 HydrophobicContact CE2-CE 3.99Å; F372-M376 HydrophobicContact CZ-CE 4.07Å; F372-M376 HydrophobicContact CZ-CG 3.99Å; F372-M376 HydrophobicContact CZ-SD 4.49Å; F372-M376 WeakPolarHBondContact O-CG 3.43Å; F372-M376 PolarHBondContact O-N 2.78Å
373	N	93.4	Very high	91.3	Very high	0 Å²	0	44.7 Å²	44.7	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-61.4	-45.1	178.2	179.7	59.3	0	0	0	111.6	Q140 S339 F343 A369 T375 M376 T377	Q140-N373 VanDerWaalsContact CD-ND2 3.32Å; Q140-N373 PolarHBondContact NE2-ND2 3.24Å; Q140-N373 PolarHBondContact NE2-OD1 2.88Å; Q140-N373 PolarHBondContact OE1-ND2 3.4Å; Q140-N373 PolarHBondContact OE1-OD1 2.94Å; S339-N373 PolarHBondContact OG-ND2 3.01Å; F343-N373 HydrophobicContact CE2-CB 4.08Å; F343-N373 HydrophobicContact CZ-CB 4.42Å; A369-N373 WeakPolarHBondContact O-CB 3.27Å; A369-N373 PolarHBondContact O-N 2.85Å; N373-T375 VanDerWaalsContact C-N 3.34Å; N373-T375 PolarHBondContact O-N 2.96Å; N373-M376 PolarHBondContact O-N 3Å; N373-T377 PolarHBondContact O-N 3.12Å; N373-T377 PolarHBondContact O-OG1 2.95Å
374	C	95.6	Very high	91.7	Very high	10 Å²	10	46.4 Å²	46.4	7%	0.068	23%	0.233	C	C	.	.	H	α-helix	trans	-56.8	-46.4	174.4	178.5	0	0	0	0	112.1	T178 L370 L371 F372 M376 T377 L378	T178-C374 HydrophobicContact CG2-CB 3.72Å; T178-C374 WeakPolarHBondContact OG1-CB 3.43Å; L370-C374 WeakPolarHBondContact O-CB 3.28Å; L370-C374 PolarHBondContact O-N 3.31Å; L371-C374 PolarHBondContact O-N 2.92Å; F372-C374 PolarHBondContact O-N 3.25Å; C374-M376 PolarHBondContact O-N 3.07Å; C374-T377 PolarHBondContact O-N 3.28Å; C374-L378 VanDerWaalsContact O-CG 3.31Å; C374-L378 WeakPolarHBondContact O-CG 3.37Å; C374-L378 PolarHBondContact O-N 2.79Å
375	T	95.8	Very high	92	Very high	76 Å²	76	41.8 Å²	41.8	47%	0.466	22%	0.215	S	C	.	.	H	α-helix	trans	-60.6	-45.2	178.5	-56.1	0	0	0	0	111.3	L371 F372 N373 L378 I379	L371-T375 WeakPolarHBondContact O-CB 3.29Å; L371-T375 PolarHBondContact O-N 3.28Å; L371-T375 PolarHBondContact O-OG1 3.05Å; F372-T375 PolarHBondContact O-N 2.8Å; N373-T375 VanDerWaalsContact C-N 3.34Å; N373-T375 PolarHBondContact O-N 2.96Å; T375-L378 PolarHBondContact O-N 2.92Å; T375-I379 WeakPolarHBondContact O-CG1 3.18Å; T375-I379 PolarHBondContact O-N 3.19Å; T375-I379 VanDerWaalsContact O-N 3.15Å
376	M	95.1	Very high	92.4	Very high	43 Å²	43	42.7 Å²	42.7	21%	0.212	22%	0.221	C	C	.	.	H	α-helix	trans	-62.4	-44.6	176.2	-70.3	-63.5	137.4	0	0	111.6	L133 P137 F372 N373 C374 L378 I379 Y380	L133-M376 HydrophobicContact CD2-SD 4.11Å; P137-M376 HydrophobicContact CB-CB 3.83Å; P137-M376 HydrophobicContact CG-CB 3.65Å; F372-M376 HydrophobicContact CD1-CG 4.29Å; F372-M376 HydrophobicContact CE1-CG 3.85Å; F372-M376 HydrophobicContact CE2-CE 3.99Å; F372-M376 HydrophobicContact CZ-CE 4.07Å; F372-M376 HydrophobicContact CZ-CG 3.99Å; F372-M376 HydrophobicContact CZ-SD 4.49Å; F372-M376 WeakPolarHBondContact O-CG 3.43Å; F372-M376 PolarHBondContact O-N 2.78Å; N373-M376 PolarHBondContact O-N 3Å; C374-M376 PolarHBondContact O-N 3.07Å; M376-L378 VanDerWaalsContact C-N 3.31Å; M376-L378 PolarHBondContact O-N 2.93Å; M376-I379 HydrophobicContact CE-CD1 4.14Å; M376-I379 WeakPolarHBondContact O-CB 3.39Å; M376-I379 PolarHBondContact O-N 3Å; M376-I379 VanDerWaalsContact O-N 3.11Å; M376-I379 HydrophobicContact SD-CD1 4.18Å; M376-Y380 WeakPolarHBondContact O-CD2 3.1Å; M376-Y380 PolarHBondContact O-N 3.43Å
377	T	96.4	Very high	92.5	Very high	0 Å²	0	44 Å²	44	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-61.5	-39.6	178.3	-56.7	0	0	0	0	111.7	P137 Q140 A141 I174 N373 C374 I379 Y380 L381	P137-T377 WeakPolarHBondContact CA-OG1 3.45Å; Q140-T377 HydrophobicContact CB-CG2 3.58Å; Q140-T377 PolarHBondContact OE1-OG1 2.76Å; A141-T377 HydrophobicContact CB-CG2 4.18Å; I174-T377 HydrophobicContact CD1-CG2 3.5Å; I174-T377 HydrophobicContact CG1-CG2 4.08Å; I174-T377 HydrophobicContact CG2-CG2 4.28Å; N373-T377 PolarHBondContact O-N 3.12Å; N373-T377 PolarHBondContact O-OG1 2.95Å; C374-T377 PolarHBondContact O-N 3.28Å; T377-I379 VanDerWaalsContact C-N 3.32Å; T377-I379 PolarHBondContact O-N 2.91Å; T377-Y380 PolarHBondContact O-N 2.87Å; T377-L381 PolarHBondContact O-N 2.98Å
378	L	96.9	Very high	92.6	Very high	59 Å²	59	46.4 Å²	46.4	31%	0.309	24%	0.236	S	C	.	.	H	α-helix	trans	-64.1	-34.6	175.2	-69.5	176	0	0	0	112.7	A171 C374 T375 M376 Y380 L381	A171-L378 HydrophobicContact CB-CD2 3.76Å; C374-L378 VanDerWaalsContact O-CG 3.31Å; C374-L378 WeakPolarHBondContact O-CG 3.37Å; C374-L378 PolarHBondContact O-N 2.79Å; T375-L378 PolarHBondContact O-N 2.92Å; M376-L378 VanDerWaalsContact C-N 3.31Å; M376-L378 PolarHBondContact O-N 2.93Å; L378-Y380 VanDerWaalsContact C-N 3.34Å; L378-L381 HydrophobicContact CD2-CD1 3.89Å; L378-L381 WeakPolarHBondContact O-CB 3.35Å; L378-L381 PolarHBondContact O-N 3.31Å
379	I	95.8	Very high	92.7	Very high	86 Å²	86	46 Å²	46	44%	0.441	23%	0.234	S	C	.	.	H	α-helix	trans	-63.5	-42.1	174.7	-67.5	165.5	0	0	0	110.4	T375 M376 T377 L381 I382	T375-I379 WeakPolarHBondContact O-CG1 3.18Å; T375-I379 PolarHBondContact O-N 3.19Å; T375-I379 VanDerWaalsContact O-N 3.15Å; M376-I379 HydrophobicContact CE-CD1 4.14Å; M376-I379 WeakPolarHBondContact O-CB 3.39Å; M376-I379 PolarHBondContact O-N 3Å; M376-I379 VanDerWaalsContact O-N 3.11Å; M376-I379 HydrophobicContact SD-CD1 4.18Å; T377-I379 VanDerWaalsContact C-N 3.32Å; T377-I379 PolarHBondContact O-N 2.91Å; I379-L381 PolarHBondContact O-N 3.42Å; I379-I382 VanDerWaalsContact O-CB 3.27Å; I379-I382 WeakPolarHBondContact O-CB 3.26Å; I379-I382 VanDerWaalsContact O-CG1 3.28Å; I379-I382 WeakPolarHBondContact O-CG1 3.49Å; I379-I382 PolarHBondContact O-N 3.21Å
380	Y	94.6	Very high	92.8	Very high	30 Å²	30	46 Å²	46	12%	0.118	23%	0.234	C	C	.	.	H	α-helix	trans	-67.7	-19.5	177.6	-81	-76.8	0	0	0	114	L133 P137 T138 M376 T377 L378 I382 V383 L389 Y392	L133-Y380 WeakPolarHBondContact O-CE2 3.38Å; L133-Y380 PolarHBondContact O-OH 3.18Å; P137-Y380 HydrophobicContact CB-CD2 3.66Å; P137-Y380 HydrophobicContact CB-CE2 3.89Å; T138-Y380 WeakPolarHBondContact OG1-CE1 3.21Å; M376-Y380 WeakPolarHBondContact O-CD2 3.1Å; M376-Y380 PolarHBondContact O-N 3.43Å; T377-Y380 PolarHBondContact O-N 2.87Å; L378-Y380 VanDerWaalsContact C-N 3.34Å; Y380-I382 PolarHBondContact O-N 2.99Å; Y380-V383 HydrophobicContact CD1-CG2 4.46Å; Y380-V383 WeakPolarHBondContact O-CB 3.46Å; Y380-V383 PolarHBondContact O-N 3.12Å; Y380-V383 VanDerWaalsContact O-N 3.17Å; Y380-L389 HydrophobicContact CD1-CD2 3.57Å; Y380-L389 HydrophobicContact CE1-CD2 4.46Å; Y380-L389 HydrophobicContact CG-CD2 4.29Å; Y380-Y392 HydrophobicContact CE1-CD2 4.42Å
381	L	94.8	Very high	92.7	Very high	13 Å²	13	46.7 Å²	46.7	7%	0.068	24%	0.237	C	C	.	.	T	Hydrogen-bonded Turn	trans	-66.2	-14.1	171	-64.3	-176.5	0	0	0	113.4	A141 I145 R167 A170 A171 I174 T377 L378 I379 V383	A141-L381 HydrophobicContact CB-CD2 4.06Å; I145-L381 HydrophobicContact CD1-CD2 4.04Å; I145-L381 HydrophobicContact CG1-CD2 3.79Å; R167-L381 PolarHBondContact NH1-O 2.87Å; A170-L381 HydrophobicContact CB-CD1 4.37Å; A170-L381 HydrophobicContact CB-CD2 4.16Å; A171-L381 HydrophobicContact CB-CD1 3.68Å; I174-L381 HydrophobicContact CD1-CD1 3.86Å; I174-L381 HydrophobicContact CD1-CD2 4.17Å; I174-L381 HydrophobicContact CD1-CG 4.21Å; T377-L381 PolarHBondContact O-N 2.98Å; L378-L381 HydrophobicContact CD2-CD1 3.89Å; L378-L381 WeakPolarHBondContact O-CB 3.35Å; L378-L381 PolarHBondContact O-N 3.31Å; I379-L381 PolarHBondContact O-N 3.42Å; L381-V383 VanDerWaalsContact C-N 3.27Å
382	I	92.3	Very high	92.5	Very high	128 Å²	128	44.2 Å²	44.2	66%	0.656	22%	0.222	S	C	*	.	T	Hydrogen-bonded Turn	trans	-70.8	-26.7	175	-58.1	170.4	0	0	0	110.9	I379 Y380 E384	I379-I382 VanDerWaalsContact O-CB 3.27Å; I379-I382 WeakPolarHBondContact O-CB 3.26Å; I379-I382 VanDerWaalsContact O-CG1 3.28Å; I379-I382 WeakPolarHBondContact O-CG1 3.49Å; I379-I382 PolarHBondContact O-N 3.21Å; Y380-I382 PolarHBondContact O-N 2.99Å; I382-E384 PolarHBondContact O-N 2.95Å
383	V	91.1	Very high	92.4	Very high	30 Å²	30	41.5 Å²	41.5	18%	0.182	21%	0.21	C	C	.	.			trans	-69.3	116.5	178.3	-177.3	0	0	0	0	109.5	R167 Y380 L381 D385 Q388 L389 Y392	R167-V383 PolarHBondContact NH1-O 2.89Å; R167-V383 PolarHBondContact NH2-O 3.45Å; Y380-V383 HydrophobicContact CD1-CG2 4.46Å; Y380-V383 WeakPolarHBondContact O-CB 3.46Å; Y380-V383 PolarHBondContact O-N 3.12Å; Y380-V383 VanDerWaalsContact O-N 3.17Å; L381-V383 VanDerWaalsContact C-N 3.27Å; V383-D385 PolarHBondContact O-N 2.67Å; V383-Q388 HydrophobicContact CG1-CB 4.19Å; V383-L389 HydrophobicContact CB-CD2 3.75Å; V383-L389 HydrophobicContact CB-CG 4.11Å; V383-L389 HydrophobicContact CG1-CD2 3.98Å; V383-L389 HydrophobicContact CG1-CG 4.03Å; V383-L389 HydrophobicContact CG2-CD2 3.86Å; V383-Y392 HydrophobicContact CG1-CE2 4.49Å; V383-Y392 HydrophobicContact CG2-CE2 4.49Å
384	E	86.1	Confident	92.4	Very high	153 Å²	153	41.5 Å²	41.5	72%	0.715	21%	0.21	S	C	*	.	S	Bend	trans	-66.2	-38.2	-172.8	-64.6	-174	172.6	0	0	113.2	Y163 R167 I382	Y163-E384 HydrophobicContact CE2-CB 4.32Å; Y163-E384 HydrophobicContact CE2-CG 4.41Å; Y163-E384 WeakPolarHBondContact OH-CA 3.3Å; R167-E384 VanDerWaalsContact NH2-C 3.3Å; R167-E384 PolarHBondContact NH2-O 2.84Å; I382-E384 PolarHBondContact O-N 2.95Å
385	D	89.1	Confident	92.1	Very high	62 Å²	62	41.7 Å²	41.7	33%	0.332	21%	0.21	S	C	.	.			trans	-98.2	122.7	-175.6	-175.1	1.8	0	0	0	112.1	V383 F387 Q388 L389	V383-D385 PolarHBondContact O-N 2.67Å; D385-F387 VanDerWaalsContact C-N 3.29Å; D385-F387 PolarHBondContact O-N 3.45Å; D385-F387 WeakPolarHBondContact OD1-CB 3.33Å; D385-F387 PolarHBondContact OD1-N 2.74Å; D385-Q388 HydrophobicContact CB-CB 4.2Å; D385-Q388 HydrophobicContact CB-CG 3.82Å; D385-Q388 PolarHBondContact O-N 3.39Å; D385-L389 PolarHBondContact O-N 3.26Å
386	V	90.9	Very high	91.9	Very high	20 Å²	20	38.3 Å²	38.3	12%	0.121	19%	0.189	C	C	.	.	H	α-helix	trans	-67.2	-31.1	176.9	-178.1	0	0	0	0	111.5	V65 I142 I145 Q388 L389 I390	V65-V386 HydrophobicContact CG1-CG1 4.17Å; I142-V386 HydrophobicContact CB-CG1 4.41Å; I142-V386 HydrophobicContact CG1-CG1 4.2Å; I142-V386 HydrophobicContact CG2-CG1 3.83Å; I145-V386 HydrophobicContact CB-CG2 4.2Å; I145-V386 HydrophobicContact CD1-CG2 4.03Å; I145-V386 HydrophobicContact CG2-CG2 3.51Å; V386-Q388 VanDerWaalsContact C-N 3.35Å; V386-L389 WeakPolarHBondContact O-CB 3.43Å; V386-L389 PolarHBondContact O-N 2.9Å; V386-I390 HydrophobicContact CG1-CD1 4.41Å; V386-I390 WeakPolarHBondContact O-CG1 3.48Å; V386-I390 PolarHBondContact O-N 2.99Å
387	F	89.9	Confident	91.7	Very high	39 Å²	39	36.7 Å²	36.7	17%	0.171	18%	0.181	C	C	.	.	H	α-helix	trans	-72	-30.6	178.8	-64.5	-72.4	0	0	0	112	V65 K68 D385 L389 I390 N391	V65-F387 HydrophobicContact CG1-CE1 4.12Å; V65-F387 HydrophobicContact CG1-CZ 4.22Å; K68-F387 HydrophobicContact CB-CZ 4.08Å; K68-F387 HydrophobicContact CD-CE2 4.28Å; K68-F387 HydrophobicContact CD-CZ 4.22Å; K68-F387 HydrophobicContact CG-CE2 4.22Å; K68-F387 HydrophobicContact CG-CZ 3.87Å; D385-F387 VanDerWaalsContact C-N 3.29Å; D385-F387 PolarHBondContact O-N 3.45Å; D385-F387 WeakPolarHBondContact OD1-CB 3.33Å; D385-F387 PolarHBondContact OD1-N 2.74Å; F387-L389 VanDerWaalsContact C-N 3.35Å; F387-I390 HydrophobicContact CD1-CD1 3.92Å; F387-I390 HydrophobicContact CE1-CD1 4.25Å; F387-I390 WeakPolarHBondContact O-CB 3.32Å; F387-I390 PolarHBondContact O-N 3.23Å; F387-N391 VanDerWaalsContact O-CG 3.27Å; F387-N391 PolarHBondContact O-N 3.42Å; F387-N391 PolarHBondContact O-OD1 3.49Å
388	Q	90.6	Very high	91.5	Very high	70 Å²	70	36.7 Å²	36.7	33%	0.327	18%	0.181	S	C	.	.	H	α-helix	trans	-63.1	-41.8	169.1	-69.1	175.2	24.3	0	0	111.6	V383 D385 V386 I390 N391 Y392	V383-Q388 HydrophobicContact CG1-CB 4.19Å; D385-Q388 HydrophobicContact CB-CB 4.2Å; D385-Q388 HydrophobicContact CB-CG 3.82Å; D385-Q388 PolarHBondContact O-N 3.39Å; V386-Q388 VanDerWaalsContact C-N 3.35Å; Q388-I390 VanDerWaalsContact C-N 3.34Å; Q388-I390 PolarHBondContact O-N 3.46Å; Q388-N391 PolarHBondContact O-N 3.05Å; Q388-Y392 WeakPolarHBondContact O-CD2 3.46Å; Q388-Y392 PolarHBondContact O-N 3.35Å
389	L	92.1	Very high	91.3	Very high	0 Å²	0	38.3 Å²	38.3	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-60.3	-44.1	172.4	-65.3	175.8	0	0	0	111.2	T138 A141 I142 I145 Y380 V383 D385 V386 F387 N391 Y392 F393	T138-L389 HydrophobicContact CG2-CB 3.71Å; T138-L389 HydrophobicContact CG2-CD2 3.99Å; T138-L389 HydrophobicContact CG2-CG 4.43Å; T138-L389 WeakPolarHBondContact CG2-O 3.29Å; A141-L389 HydrophobicContact CB-CD1 4.21Å; I142-L389 HydrophobicContact CD1-CB 3.88Å; I142-L389 HydrophobicContact CG1-CB 3.6Å; I142-L389 HydrophobicContact CG1-CD1 4.17Å; I145-L389 HydrophobicContact CD1-CD1 3.75Å; Y380-L389 HydrophobicContact CD1-CD2 3.57Å; Y380-L389 HydrophobicContact CE1-CD2 4.46Å; Y380-L389 HydrophobicContact CG-CD2 4.29Å; V383-L389 HydrophobicContact CB-CD2 3.75Å; V383-L389 HydrophobicContact CB-CG 4.11Å; V383-L389 HydrophobicContact CG1-CD2 3.98Å; V383-L389 HydrophobicContact CG1-CG 4.03Å; V383-L389 HydrophobicContact CG2-CD2 3.86Å; D385-L389 PolarHBondContact O-N 3.26Å; V386-L389 WeakPolarHBondContact O-CB 3.43Å; V386-L389 PolarHBondContact O-N 2.9Å; F387-L389 VanDerWaalsContact C-N 3.35Å; L389-N391 VanDerWaalsContact C-N 3.26Å; L389-N391 PolarHBondContact O-N 3.34Å; L389-Y392 HydrophobicContact CD2-CD2 4.23Å; L389-Y392 PolarHBondContact O-N 2.84Å; L389-F393 WeakPolarHBondContact O-CB 3.5Å; L389-F393 PolarHBondContact O-N 2.98Å
390	I	92	Very high	91.2	Very high	0 Å²	0	34.4 Å²	34.4	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-59	-39.6	175.8	-71.3	169	0	0	0	111	V65 I142 F245 V386 F387 Q388 S394	V65-I390 HydrophobicContact CG1-CD1 4.01Å; I142-I390 HydrophobicContact CD1-CB 4.49Å; I142-I390 HydrophobicContact CD1-CG1 3.73Å; I142-I390 HydrophobicContact CG1-CG1 4.33Å; I142-I390 HydrophobicContact CG2-CG1 4.42Å; F245-I390 HydrophobicContact CB-CG2 3.89Å; F245-I390 HydrophobicContact CD1-CD1 4.14Å; F245-I390 HydrophobicContact CD1-CG1 4.12Å; F245-I390 HydrophobicContact CD2-CG1 4.44Å; F245-I390 HydrophobicContact CE1-CG1 4.4Å; F245-I390 HydrophobicContact CG-CG1 4.15Å; F245-I390 HydrophobicContact CG-CG2 4.22Å; V386-I390 HydrophobicContact CG1-CD1 4.41Å; V386-I390 WeakPolarHBondContact O-CG1 3.48Å; V386-I390 PolarHBondContact O-N 2.99Å; F387-I390 HydrophobicContact CD1-CD1 3.92Å; F387-I390 HydrophobicContact CE1-CD1 4.25Å; F387-I390 WeakPolarHBondContact O-CB 3.32Å; F387-I390 PolarHBondContact O-N 3.23Å; Q388-I390 VanDerWaalsContact C-N 3.34Å; Q388-I390 PolarHBondContact O-N 3.46Å; I390-S394 WeakPolarHBondContact O-CB 3.42Å; I390-S394 PolarHBondContact O-N 2.94Å; I390-S394 PolarHBondContact O-OG 3.01Å
391	N	89.3	Confident	91.1	Very high	16 Å²	16	33 Å²	33	9%	0.086	16%	0.16	C	C	.	.	H	α-helix	trans	-67.8	-44.7	177.6	-68	-7.9	0	0	0	112.1	Y241 F387 Q388 L389 F393 S394 F395 D447	Y241-N391 HydrophobicContact CD2-CB 4.45Å; F387-N391 VanDerWaalsContact O-CG 3.27Å; F387-N391 PolarHBondContact O-N 3.42Å; F387-N391 PolarHBondContact O-OD1 3.49Å; Q388-N391 PolarHBondContact O-N 3.05Å; L389-N391 VanDerWaalsContact C-N 3.26Å; L389-N391 PolarHBondContact O-N 3.34Å; N391-F393 VanDerWaalsContact C-N 3.34Å; N391-F393 PolarHBondContact O-N 3.42Å; N391-S394 PolarHBondContact O-N 3.06Å; N391-F395 WeakPolarHBondContact O-CB 3.25Å; N391-F395 PolarHBondContact O-N 3.33Å; N391-D447 PolarHBondContact ND2-OD2 3.38Å
392	Y	87.8	Confident	91.2	Very high	30 Å²	30	32.7 Å²	32.7	12%	0.118	16%	0.16	C	C	.	.	H	α-helix	trans	-57.1	-48.1	174.4	-66.5	-35.6	0	0	0	111.8	Y380 V383 Q388 L389 S396 N450	Y380-Y392 HydrophobicContact CE1-CD2 4.42Å; V383-Y392 HydrophobicContact CG1-CE2 4.49Å; V383-Y392 HydrophobicContact CG2-CE2 4.49Å; Q388-Y392 WeakPolarHBondContact O-CD2 3.46Å; Q388-Y392 PolarHBondContact O-N 3.35Å; L389-Y392 HydrophobicContact CD2-CD2 4.23Å; L389-Y392 PolarHBondContact O-N 2.84Å; Y392-S396 PolarHBondContact O-N 3.37Å; Y392-N450 HydrophobicContact CD1-CB 3.84Å; Y392-N450 HydrophobicContact CE1-CB 3.34Å; Y392-N450 WeakPolarHBondContact CE1-OD1 3.44Å; Y392-N450 VanDerWaalsContact CZ-OD1 3.27Å; Y392-N450 PolarHBondContact OH-OD1 2.99Å
393	F	91.8	Very high	91.3	Very high	7 Å²	7	28.3 Å²	28.3	3%	0.031	14%	0.138	C	C	.	.	H	α-helix	trans	-59.4	-53.7	176.5	170	-90.3	0	0	0	110.7	V135 T138 F245 L389 N391 F395 S396 Y397	V135-F393 HydrophobicContact CB-CD2 4.49Å; V135-F393 HydrophobicContact CG1-CD2 3.77Å; V135-F393 HydrophobicContact CG1-CE2 3.45Å; V135-F393 VanDerWaalsContact CG1-CE2 3.45Å; V135-F393 HydrophobicContact CG1-CZ 4.41Å; V135-F393 WeakPolarHBondContact O-CD2 3.43Å; T138-F393 HydrophobicContact CG2-CB 3.92Å; F245-F393 AromaticContact CD2-CD1 3.6Å; F245-F393 HydrophobicContact CD2-CD1 3.6Å; F245-F393 AromaticContact CD2-CE1 3.72Å; F245-F393 HydrophobicContact CD2-CE1 3.72Å; F245-F393 HydrophobicContact CD2-CG 4.28Å; F245-F393 HydrophobicContact CD2-CZ 4.48Å; F245-F393 HydrophobicContact CE2-CD1 4.15Å; F245-F393 HydrophobicContact CE2-CE1 4.28Å; F245-F393 HydrophobicContact CE2-CG 4.44Å; L389-F393 WeakPolarHBondContact O-CB 3.5Å; L389-F393 PolarHBondContact O-N 2.98Å; N391-F393 VanDerWaalsContact C-N 3.34Å; N391-F393 PolarHBondContact O-N 3.42Å; F393-F395 PolarHBondContact O-N 3.37Å; F393-S396 PolarHBondContact O-N 2.82Å; F393-Y397 HydrophobicContact CE1-CD1 4.2Å; F393-Y397 HydrophobicContact CE1-CG 4.12Å; F393-Y397 HydrophobicContact CE2-CD2 4.43Å; F393-Y397 HydrophobicContact CE2-CG 4.49Å; F393-Y397 HydrophobicContact CZ-CD1 4.24Å; F393-Y397 HydrophobicContact CZ-CD2 4.07Å; F393-Y397 AromaticContact CZ-CG 3.9Å; F393-Y397 HydrophobicContact CZ-CG 3.9Å; F393-Y397 WeakPolarHBondContact O-CB 3.29Å; F393-Y397 PolarHBondContact O-N 3.4Å
394	S	91.4	Very high	91.5	Very high	0 Å²	0	26.9 Å²	26.9	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-65.2	-44.5	-170.2	-63.5	0	0	0	0	111.8	I390 N391 S396 Y397 W398	I390-S394 WeakPolarHBondContact O-CB 3.42Å; I390-S394 PolarHBondContact O-N 2.94Å; I390-S394 PolarHBondContact O-OG 3.01Å; N391-S394 PolarHBondContact O-N 3.06Å; S394-S396 PolarHBondContact O-N 2.96Å; S394-Y397 PolarHBondContact O-N 3.32Å; S394-W398 WeakPolarHBondContact O-CB 3.31Å; S394-W398 PolarHBondContact O-N 3.5Å
395	F	90.4	Very high	91.9	Very high	14 Å²	14	19.6 Å²	19.6	6%	0.061	10%	0.095	C	C	.	.	H	α-helix	trans	-57.1	-54.1	178.7	177.1	-91.3	0	0	0	111.4	Y241 N391 F393 F399 V440 L444 I455	Y241-F395 HydrophobicContact CE2-CB 4.3Å; Y241-F395 WeakPolarHBondContact OH-CA 3.14Å; N391-F395 WeakPolarHBondContact O-CB 3.25Å; N391-F395 PolarHBondContact O-N 3.33Å; F393-F395 PolarHBondContact O-N 3.37Å; F395-F399 VanDerWaalsContact O-CB 3.29Å; F395-F399 WeakPolarHBondContact O-CB 3.22Å; F395-F399 PolarHBondContact O-N 3.29Å; F395-F399 VanDerWaalsContact O-N 3.14Å; F395-V440 HydrophobicContact CE2-CB 4.48Å; F395-V440 HydrophobicContact CE2-CG1 3.75Å; F395-V440 HydrophobicContact CZ-CG1 4.06Å; F395-L444 HydrophobicContact CE2-CD2 4.15Å; F395-L444 HydrophobicContact CE2-CG 4.11Å; F395-L444 HydrophobicContact CZ-CD2 4.25Å; F395-I455 HydrophobicContact CE1-CG1 3.87Å; F395-I455 HydrophobicContact CZ-CD1 4.02Å; F395-I455 HydrophobicContact CZ-CG1 3.88Å
396	S	91.1	Very high	92.3	Very high	4 Å²	4	19.7 Å²	19.7	3%	0.028	10%	0.097	C	C	.	.	H	α-helix	trans	-66.9	-44.4	-179.1	-70.3	0	0	0	0	112.2	Y392 F393 S394 F400	Y392-S396 PolarHBondContact O-N 3.37Å; F393-S396 PolarHBondContact O-N 2.82Å; S394-S396 PolarHBondContact O-N 2.96Å; S396-F400 WeakPolarHBondContact O-CD2 3.39Å; S396-F400 PolarHBondContact O-N 2.85Å
397	Y	91.9	Very high	92.5	Very high	10 Å²	10	18.8 Å²	18.8	4%	0.039	9%	0.092	C	C	.	.	H	α-helix	trans	-61.3	-53.4	-178.6	-178	-104.1	0	0	0	111.2	V135 D251 F393 S394 F399 F400 V401	V135-Y397 HydrophobicContact CG1-CD2 3.99Å; D251-Y397 PolarHBondContact OD1-OH 2.99Å; D251-Y397 PolarHBondContact OD2-OH 2.95Å; F393-Y397 HydrophobicContact CE1-CD1 4.2Å; F393-Y397 HydrophobicContact CE1-CG 4.12Å; F393-Y397 HydrophobicContact CE2-CD2 4.43Å; F393-Y397 HydrophobicContact CE2-CG 4.49Å; F393-Y397 HydrophobicContact CZ-CD1 4.24Å; F393-Y397 HydrophobicContact CZ-CD2 4.07Å; F393-Y397 AromaticContact CZ-CG 3.9Å; F393-Y397 HydrophobicContact CZ-CG 3.9Å; F393-Y397 WeakPolarHBondContact O-CB 3.29Å; F393-Y397 PolarHBondContact O-N 3.4Å; S394-Y397 PolarHBondContact O-N 3.32Å; Y397-F399 PolarHBondContact O-N 3.1Å; Y397-F400 PolarHBondContact O-N 3.13Å; Y397-V401 HydrophobicContact CD1-CG2 4.14Å; Y397-V401 HydrophobicContact CD2-CG2 4.32Å; Y397-V401 HydrophobicContact CE1-CG2 3.87Å; Y397-V401 HydrophobicContact CE2-CG2 4.06Å; Y397-V401 HydrophobicContact CG-CG2 4.36Å; Y397-V401 VanDerWaalsContact O-CG2 3.25Å; Y397-V401 WeakPolarHBondContact O-CG2 3.35Å; Y397-V401 PolarHBondContact O-N 3.26Å
398	W	91.8	Very high	92.7	Very high	0 Å²	0	17.1 Å²	17.1	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-69.5	-30.9	-176.9	-66.6	117.1	0	0	0	113.4	F90 L244 W250 S394 V401 G402 F432 L439	F90-W398 HydrophobicContact CD1-CH2 4.45Å; F90-W398 HydrophobicContact CD1-CZ3 4.36Å; F90-W398 HydrophobicContact CE1-CD2 4.18Å; F90-W398 AromaticContact CE1-CE3 3.64Å; F90-W398 HydrophobicContact CE1-CE3 3.64Å; F90-W398 AromaticContact CE1-CH2 3.95Å; F90-W398 HydrophobicContact CE1-CH2 3.95Å; F90-W398 HydrophobicContact CE1-CZ2 4.47Å; F90-W398 AromaticContact CE1-CZ3 3.51Å; F90-W398 HydrophobicContact CE1-CZ3 3.51Å; F90-W398 HydrophobicContact CZ-CE3 4.11Å; F90-W398 HydrophobicContact CZ-CZ3 4.26Å; L244-W398 HydrophobicContact CB-CZ2 3.63Å; L244-W398 HydrophobicContact CD1-CD2 4.44Å; L244-W398 HydrophobicContact CD1-CZ2 4.14Å; L244-W398 HydrophobicContact CD2-CH2 4.28Å; L244-W398 HydrophobicContact CD2-CZ2 3.93Å; L244-W398 HydrophobicContact CG-CZ2 4.11Å; W250-W398 HydrophobicContact CZ2-CH2 4.44Å; W250-W398 HydrophobicContact CZ2-CZ3 4.15Å; S394-W398 WeakPolarHBondContact O-CB 3.31Å; S394-W398 PolarHBondContact O-N 3.5Å; W398-V401 HydrophobicContact CE3-CB 4.2Å; W398-V401 HydrophobicContact CE3-CG1 4.17Å; W398-V401 HydrophobicContact CZ3-CG1 4.16Å; W398-G402 PolarHBondContact O-N 3.1Å; W398-F432 HydrophobicContact CE3-CZ 4.31Å; W398-F432 HydrophobicContact CZ3-CE2 4.5Å; W398-F432 HydrophobicContact CZ3-CZ 4.13Å; W398-L439 HydrophobicContact CB-CD1 4.46Å; W398-L439 HydrophobicContact CG-CD1 4.26Å
399	F	92.6	Very high	92.9	Very high	92 Å²	92	15.9 Å²	15.9	40%	0.404	8%	0.08	S	C	.	.	H	α-helix	trans	-57.3	-50.7	171.1	174.5	-100.3	0	0	0	111.4	F395 Y397 G402 L403 V440	F395-F399 VanDerWaalsContact O-CB 3.29Å; F395-F399 WeakPolarHBondContact O-CB 3.22Å; F395-F399 PolarHBondContact O-N 3.29Å; F395-F399 VanDerWaalsContact O-N 3.14Å; Y397-F399 PolarHBondContact O-N 3.1Å; F399-G402 PolarHBondContact O-N 3.09Å; F399-L403 HydrophobicContact CE1-CD2 4.42Å; F399-L403 WeakPolarHBondContact O-CB 3.41Å; F399-L403 PolarHBondContact O-N 2.99Å; F399-V440 HydrophobicContact CB-CG2 3.93Å; F399-V440 HydrophobicContact CD2-CG1 4.26Å; F399-V440 HydrophobicContact CD2-CG2 4.17Å
400	F	93.5	Very high	93	Very high	5 Å²	5	19.3 Å²	19.3	2%	0.022	9%	0.094	C	C	.	.	H	α-helix	trans	-76.1	-30.6	-177.7	-79.6	-62.8	0	0	0	113.9	I115 I126 R127 V130 S396 Y397 L403 S404	I115-F400 HydrophobicContact CD1-CD1 4.09Å; I126-F400 HydrophobicContact CG2-CZ 4.07Å; R127-F400 HydrophobicContact CB-CD1 3.83Å; R127-F400 HydrophobicContact CB-CE1 3.84Å; R127-F400 HydrophobicContact CB-CG 4.48Å; R127-F400 HydrophobicContact CG-CD1 4.17Å; R127-F400 HydrophobicContact CG-CG 4.43Å; V130-F400 HydrophobicContact CB-CD2 4.41Å; V130-F400 HydrophobicContact CB-CE2 3.59Å; V130-F400 HydrophobicContact CB-CZ 4.22Å; V130-F400 HydrophobicContact CG1-CD2 4.27Å; V130-F400 HydrophobicContact CG1-CE2 3.7Å; V130-F400 HydrophobicContact CG2-CE2 3.77Å; V130-F400 HydrophobicContact CG2-CZ 4.04Å; S396-F400 WeakPolarHBondContact O-CD2 3.39Å; S396-F400 PolarHBondContact O-N 2.85Å; Y397-F400 PolarHBondContact O-N 3.13Å; F400-L403 HydrophobicContact CD1-CD2 4.02Å; F400-L403 HydrophobicContact CE1-CD2 4.24Å; F400-L403 PolarHBondContact O-N 3.37Å; F400-S404 PolarHBondContact O-N 3.33Å; F400-S404 PolarHBondContact O-OG 3.39Å
401	V	93.6	Very high	93.1	Very high	0 Å²	0	19.7 Å²	19.7	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-63.8	-46.8	171.2	174	0	0	0	0	109.6	Y98 W250 Y397 W398 L403 S404 V405 F432	Y98-V401 HydrophobicContact CE2-CG1 3.68Å; Y98-V401 WeakPolarHBondContact OH-CA 3.49Å; W250-V401 HydrophobicContact CH2-CG1 3.93Å; W250-V401 HydrophobicContact CZ2-CG1 4.07Å; Y397-V401 HydrophobicContact CD1-CG2 4.14Å; Y397-V401 HydrophobicContact CD2-CG2 4.32Å; Y397-V401 HydrophobicContact CE1-CG2 3.87Å; Y397-V401 HydrophobicContact CE2-CG2 4.06Å; Y397-V401 HydrophobicContact CG-CG2 4.36Å; Y397-V401 VanDerWaalsContact O-CG2 3.25Å; Y397-V401 WeakPolarHBondContact O-CG2 3.35Å; Y397-V401 PolarHBondContact O-N 3.26Å; W398-V401 HydrophobicContact CE3-CB 4.2Å; W398-V401 HydrophobicContact CE3-CG1 4.17Å; W398-V401 HydrophobicContact CZ3-CG1 4.16Å; V401-L403 PolarHBondContact O-N 2.84Å; V401-S404 WeakPolarHBondContact O-CB 3.41Å; V401-S404 PolarHBondContact O-N 2.54Å; V401-V405 PolarHBondContact O-N 2.99Å; V401-F432 HydrophobicContact CG1-CE1 3.82Å; V401-F432 HydrophobicContact CG1-CZ 3.63Å
402	G	95.1	Very high	93.2	Very high	6 Å²	6	20.5 Å²	20.5	6%	0.062	10%	0.098	C	C	.	.	H	α-helix	trans	-57.1	-46.4	172.2	0	0	0	0	0	112.3	W398 F399 S404 V405 V406	W398-G402 PolarHBondContact O-N 3.1Å; F399-G402 PolarHBondContact O-N 3.09Å; G402-S404 VanDerWaalsContact C-N 3.28Å; G402-S404 PolarHBondContact O-N 3.19Å; G402-V405 PolarHBondContact O-N 3.12Å; G402-V405 VanDerWaalsContact O-N 3.08Å; G402-V406 WeakPolarHBondContact O-CG2 3.46Å; G402-V406 PolarHBondContact O-N 2.72Å
403	L	95.3	Very high	93.4	Very high	37 Å²	37	29 Å²	29	19%	0.194	13%	0.13	C	C	.	.	H	α-helix	trans	-59.9	-37.4	177.4	-173.1	60	0	0	0	112.5	I115 F119 I123 F399 F400 V401 V405 V406 G407	I115-L403 HydrophobicContact CD1-CD2 4.23Å; I115-L403 HydrophobicContact CD1-CG 4.39Å; F119-L403 HydrophobicContact CD2-CD1 4.48Å; F119-L403 HydrophobicContact CD2-CG 4.47Å; F119-L403 HydrophobicContact CE2-CD1 3.85Å; F119-L403 HydrophobicContact CE2-CG 4.03Å; F119-L403 WeakPolarHBondContact CE2-O 3.03Å; F119-L403 HydrophobicContact CZ-CD1 4.14Å; I123-L403 HydrophobicContact CG2-CD2 3.6Å; F399-L403 HydrophobicContact CE1-CD2 4.42Å; F399-L403 WeakPolarHBondContact O-CB 3.41Å; F399-L403 PolarHBondContact O-N 2.99Å; F400-L403 HydrophobicContact CD1-CD2 4.02Å; F400-L403 HydrophobicContact CE1-CD2 4.24Å; F400-L403 PolarHBondContact O-N 3.37Å; V401-L403 PolarHBondContact O-N 2.84Å; L403-V405 VanDerWaalsContact C-N 3.33Å; L403-V405 PolarHBondContact O-N 2.69Å; L403-V406 WeakPolarHBondContact O-CB 3.41Å; L403-V406 PolarHBondContact O-N 3.46Å; L403-G407 PolarHBondContact O-N 3.18Å
404	S	94.9	Very high	93.5	Very high	0 Å²	0	34.4 Å²	34.4	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-64.1	-39.4	175.8	-54.2	0	0	0	0	111.7	Y98 S111 F400 V401 G402 G407 Q408	Y98-S404 WeakPolarHBondContact OH-CB 3.29Å; Y98-S404 PolarHBondContact OH-OG 3.06Å; Y98-S404 VanDerWaalsContact OH-OG 3.1Å; S111-S404 WeakPolarHBondContact CB-OG 3.39Å; F400-S404 PolarHBondContact O-N 3.33Å; F400-S404 PolarHBondContact O-OG 3.39Å; V401-S404 WeakPolarHBondContact O-CB 3.41Å; V401-S404 PolarHBondContact O-N 2.54Å; G402-S404 VanDerWaalsContact C-N 3.28Å; G402-S404 PolarHBondContact O-N 3.19Å; S404-G407 CarbonylContact O-C 3.58Å; S404-G407 WeakPolarHBondContact O-CA 3.48Å; S404-G407 PolarHBondContact O-N 3.24Å; S404-G407 VanDerWaalsContact O-N 3.14Å; S404-Q408 PolarHBondContact O-N 3Å
405	V	95.6	Very high	93.6	Very high	0 Å²	0	37.9 Å²	37.9	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-71.9	-33.5	175.7	-178.8	0	0	0	0	111.8	C97 Y98 V401 G402 L403 G407 Q408 L409 P429 F432	C97-V405 HydrophobicContact CB-CG1 4.18Å; C97-V405 HydrophobicContact CB-CG2 3.95Å; Y98-V405 HydrophobicContact CD2-CG2 4.2Å; Y98-V405 HydrophobicContact CE2-CG2 3.99Å; V401-V405 PolarHBondContact O-N 2.99Å; G402-V405 PolarHBondContact O-N 3.12Å; G402-V405 VanDerWaalsContact O-N 3.08Å; L403-V405 VanDerWaalsContact C-N 3.33Å; L403-V405 PolarHBondContact O-N 2.69Å; V405-G407 VanDerWaalsContact C-N 3.26Å; V405-G407 PolarHBondContact O-N 3.47Å; V405-Q408 VanDerWaalsContact O-CB 3.22Å; V405-Q408 WeakPolarHBondContact O-CB 3.44Å; V405-Q408 PolarHBondContact O-N 3.46Å; V405-Q408 VanDerWaalsContact O-N 3.15Å; V405-L409 PolarHBondContact O-N 3.29Å; V405-L409 VanDerWaalsContact O-N 3.12Å; V405-P429 HydrophobicContact CG1-CB 3.46Å; V405-P429 VanDerWaalsContact CG1-CB 3.46Å; V405-F432 HydrophobicContact CB-CD1 3.97Å; V405-F432 HydrophobicContact CB-CE1 4.41Å; V405-F432 HydrophobicContact CG1-CD1 4.11Å; V405-F432 HydrophobicContact CG2-CD1 3.63Å; V405-F432 HydrophobicContact CG2-CE1 3.76Å
406	V	96.5	Very high	93.5	Very high	63 Å²	63	41 Å²	41	38%	0.382	19%	0.191	S	C	.	.	H	α-helix	trans	-60.7	-40	166.8	177.9	0	0	0	0	110.3	F119 G402 L403 Q408 L409 Y410	F119-V406 HydrophobicContact CZ-CB 4.47Å; F119-V406 HydrophobicContact CZ-CG1 4.11Å; G402-V406 WeakPolarHBondContact O-CG2 3.46Å; G402-V406 PolarHBondContact O-N 2.72Å; L403-V406 WeakPolarHBondContact O-CB 3.41Å; L403-V406 PolarHBondContact O-N 3.46Å; V406-Q408 VanDerWaalsContact C-N 3.31Å; V406-Q408 PolarHBondContact O-N 3.35Å; V406-L409 PolarHBondContact O-N 2.87Å; V406-L409 VanDerWaalsContact O-N 3.16Å; V406-Y410 WeakPolarHBondContact O-CB 3.42Å; V406-Y410 PolarHBondContact O-N 3.38Å
407	G	94.3	Very high	93.5	Very high	1 Å²	1	49 Å²	49	1%	0.01	23%	0.228	C	C	.	.	H	α-helix	trans	-57.6	-40.4	171.9	0	0	0	0	0	112.8	L403 S404 V405 L409 Y410 L411	L403-G407 PolarHBondContact O-N 3.18Å; S404-G407 CarbonylContact O-C 3.58Å; S404-G407 WeakPolarHBondContact O-CA 3.48Å; S404-G407 PolarHBondContact O-N 3.24Å; S404-G407 VanDerWaalsContact O-N 3.14Å; V405-G407 VanDerWaalsContact C-N 3.26Å; V405-G407 PolarHBondContact O-N 3.47Å; G407-L409 PolarHBondContact O-N 2.98Å; G407-Y410 PolarHBondContact O-N 3.13Å; G407-L411 WeakPolarHBondContact O-CB 3.49Å; G407-L411 VanDerWaalsContact O-CG 3.32Å; G407-L411 WeakPolarHBondContact O-CG 3.31Å; G407-L411 PolarHBondContact O-N 3.45Å
408	Q	94.1	Very high	93.4	Very high	4 Å²	4	51.1 Å²	51.1	2%	0.019	24%	0.236	C	C	.	.	H	α-helix	trans	-58.8	-47	173	-169	-165.2	-20	0	0	112.1	C97 E100 L101 S404 V405 V406 Y410 L411 R412	C97-Q408 PolarHBondContact O-OE1 3.46Å; E100-Q408 PolarHBondContact OE1-NE2 2.98Å; E100-Q408 PolarHBondContact OE2-NE2 3.38Å; L101-Q408 HydrophobicContact CD1-CB 4.14Å; L101-Q408 HydrophobicContact CD2-CB 3.69Å; L101-Q408 HydrophobicContact CD2-CG 3.89Å; L101-Q408 HydrophobicContact CG-CB 3.93Å; L101-Q408 HydrophobicContact CG-CG 3.99Å; S404-Q408 PolarHBondContact O-N 3Å; V405-Q408 VanDerWaalsContact O-CB 3.22Å; V405-Q408 WeakPolarHBondContact O-CB 3.44Å; V405-Q408 PolarHBondContact O-N 3.46Å; V405-Q408 VanDerWaalsContact O-N 3.15Å; V406-Q408 VanDerWaalsContact C-N 3.31Å; V406-Q408 PolarHBondContact O-N 3.35Å; Q408-Y410 VanDerWaalsContact C-N 3.35Å; Q408-L411 PolarHBondContact O-N 3.2Å; Q408-R412 WeakPolarHBondContact O-CG 3.34Å; Q408-R412 PolarHBondContact O-N 2.86Å
409	L	95.1	Very high	93.2	Very high	45 Å²	45	56.4 Å²	56.4	24%	0.236	27%	0.27	C	S	.	.	H	α-helix	trans	-64.3	-41	177.6	-68.9	174.1	0	0	0	111.4	V405 V406 G407 R412 W413 V426 P429 I430	V405-L409 PolarHBondContact O-N 3.29Å; V405-L409 VanDerWaalsContact O-N 3.12Å; V406-L409 PolarHBondContact O-N 2.87Å; V406-L409 VanDerWaalsContact O-N 3.16Å; G407-L409 PolarHBondContact O-N 2.98Å; L409-R412 WeakPolarHBondContact O-CB 3.26Å; L409-R412 PolarHBondContact O-N 3.5Å; L409-W413 PolarHBondContact O-N 3.28Å; L409-V426 HydrophobicContact CD2-CG1 3.9Å; L409-P429 HydrophobicContact CD1-CB 4.45Å; L409-P429 HydrophobicContact CD2-CB 3.97Å; L409-P429 HydrophobicContact CD2-CG 3.78Å; L409-P429 HydrophobicContact CG-CB 4.14Å; L409-P429 HydrophobicContact CG-CG 4.49Å; L409-I430 HydrophobicContact CD1-CG1 4.33Å
410	Y	95.1	Very high	93.1	Very high	72 Å²	72	53.8 Å²	53.8	28%	0.282	26%	0.258	S	S	.	.	H	α-helix	trans	-62.4	-46.7	176.1	175.7	-104.6	0	0	0	112	A118 F119 V406 G407 Q408 R412 W413 K414	A118-Y410 HydrophobicContact CB-CD1 4.39Å; A118-Y410 WeakPolarHBondContact O-CD1 3.35Å; A118-Y410 WeakPolarHBondContact O-CE1 3.17Å; F119-Y410 HydrophobicContact CE1-CG 4.43Å; V406-Y410 WeakPolarHBondContact O-CB 3.42Å; V406-Y410 PolarHBondContact O-N 3.38Å; G407-Y410 PolarHBondContact O-N 3.13Å; Q408-Y410 VanDerWaalsContact C-N 3.35Å; Y410-R412 VanDerWaalsContact C-N 3.29Å; Y410-R412 PolarHBondContact O-N 3.38Å; Y410-W413 HydrophobicContact CD2-CE3 4.47Å; Y410-W413 HydrophobicContact CE2-CE3 4.46Å; Y410-W413 PolarHBondContact O-N 3.07Å; Y410-W413 VanDerWaalsContact O-N 3.08Å; Y410-K414 HydrophobicContact CE1-CB 4.43Å; Y410-K414 HydrophobicContact CE1-CD 3.7Å; Y410-K414 WeakPolarHBondContact O-CB 3.33Å; Y410-K414 PolarHBondContact O-N 3.4Å; Y410-K414 WeakPolarHBondContact OH-CD 3.22Å; Y410-K414 WeakPolarHBondContact OH-CE 3.22Å; Y410-K414 PolarHBondContact OH-NZ 3.5Å; Y410-K414 VanDerWaalsContact OH-NZ 3.07Å
411	L	93	Very high	92.9	Very high	7 Å²	7	56.4 Å²	56.4	4%	0.037	28%	0.275	C	S	.	.	H	α-helix	trans	-64.5	-32.4	177.2	-72.4	172.5	0	0	0	112.2	I105 A118 G407 Q408 W413 E415 R420	I105-L411 HydrophobicContact CD1-CD1 3.84Å; A118-L411 HydrophobicContact CB-CD1 4.17Å; A118-L411 HydrophobicContact CB-CG 4.12Å; G407-L411 WeakPolarHBondContact O-CB 3.49Å; G407-L411 VanDerWaalsContact O-CG 3.32Å; G407-L411 WeakPolarHBondContact O-CG 3.31Å; G407-L411 PolarHBondContact O-N 3.45Å; Q408-L411 PolarHBondContact O-N 3.2Å; L411-W413 VanDerWaalsContact C-N 3.27Å; L411-W413 PolarHBondContact O-N 3.4Å; L411-E415 CarbonylContact O-C 3.18Å; L411-E415 VanDerWaalsContact O-C 3.32Å; L411-E415 WeakPolarHBondContact O-CA 3.27Å; L411-E415 PolarHBondContact O-N 3.35Å; L411-E415 VanDerWaalsContact O-O 3.13Å; L411-R420 PolarHBondContact O-NH2 3.41Å
412	R	92.3	Very high	92.7	Very high	33 Å²	33	58.3 Å²	58.3	13%	0.125	29%	0.285	C	S	.	.	H	α-helix	trans	-62.8	-34.2	172	-79.9	178.7	170.3	-143.4	2.2	113.2	E100 Q408 L409 Y410 R420 L424	E100-R412 IonicContact OE1-CZ 3.77Å; E100-R412 IonicContact OE1-NE 3.96Å; E100-R412 PolarHBondContact OE1-NE 2.93Å; E100-R412 IonicContact OE1-NH2 2.69Å; E100-R412 PolarHBondContact OE1-NH2 3.07Å; E100-R412 IonicContact OE2-CZ 2.84Å; E100-R412 IonicContact OE2-NH2 3Å; E100-R412 PolarHBondContact OE2-NH2 3.04Å; Q408-R412 WeakPolarHBondContact O-CG 3.34Å; Q408-R412 PolarHBondContact O-N 2.86Å; L409-R412 WeakPolarHBondContact O-CB 3.26Å; L409-R412 PolarHBondContact O-N 3.5Å; Y410-R412 VanDerWaalsContact C-N 3.29Å; Y410-R412 PolarHBondContact O-N 3.38Å; R412-R420 VanDerWaalsContact CA-NH2 3.3Å; R412-L424 PolarHBondContact NH1-O 3.36Å; R412-L424 PolarHBondContact NH2-O 3.47Å
413	W	92.9	Very high	92.4	Very high	209 Å²	209	65.2 Å²	65.2	79%	0.792	31%	0.313	S	S	*	.	H	α-helix	trans	-83.4	-45.1	179.5	-179.5	64.8	0	0	0	112.6	L409 Y410 L411	L409-W413 PolarHBondContact O-N 3.28Å; Y410-W413 HydrophobicContact CD2-CE3 4.47Å; Y410-W413 HydrophobicContact CE2-CE3 4.46Å; Y410-W413 PolarHBondContact O-N 3.07Å; Y410-W413 VanDerWaalsContact O-N 3.08Å; L411-W413 VanDerWaalsContact C-N 3.27Å; L411-W413 PolarHBondContact O-N 3.4Å
414	K	93.3	Very high	92.2	Very high	120 Å²	120	64.8 Å²	64.8	52%	0.522	31%	0.311	S	S	.	.	H	α-helix	trans	-75.8	-39.9	-177.4	-166.8	-169.6	-165.4	171.3	0	113.2	Y410 P416	Y410-K414 HydrophobicContact CE1-CB 4.43Å; Y410-K414 HydrophobicContact CE1-CD 3.7Å; Y410-K414 WeakPolarHBondContact O-CB 3.33Å; Y410-K414 PolarHBondContact O-N 3.4Å; Y410-K414 WeakPolarHBondContact OH-CD 3.22Å; Y410-K414 WeakPolarHBondContact OH-CE 3.22Å; Y410-K414 PolarHBondContact OH-NZ 3.5Å; Y410-K414 VanDerWaalsContact OH-NZ 3.07Å; K414-P416 VanDerWaalsContact C-CD 3.49Å; K414-P416 WeakPolarHBondContact O-CD 3.41Å
415	E	92.5	Very high	92.1	Very high	74 Å²	74	68.2 Å²	68.2	35%	0.346	34%	0.335	S	S	.	.			trans	-125.6	71.7	-176	-66	178.3	-174.3	0	0	110.3	L411 E417 R418 R420	L411-E415 CarbonylContact O-C 3.18Å; L411-E415 VanDerWaalsContact O-C 3.32Å; L411-E415 WeakPolarHBondContact O-CA 3.27Å; L411-E415 PolarHBondContact O-N 3.35Å; L411-E415 VanDerWaalsContact O-O 3.13Å; E415-E417 VanDerWaalsContact C-N 3.33Å; E415-E417 PolarHBondContact O-N 2.8Å; E415-R418 HydrophobicContact CB-CB 4.33Å; E415-R418 IonicContact OE2-CZ 2.93Å; E415-R418 IonicContact OE2-NH1 3.73Å; E415-R418 PolarHBondContact OE2-NH1 3.34Å; E415-R420 PolarHBondContact O-NH2 3.49Å
416	P	89.8	Confident	92	Very high	78 Å²	78	71.5 Å²	71.5	51%	0.506	36%	0.355	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.5	-34.9	-176.5	24.9	-32.8	0	0	0	112.7	K414 R418 R420	K414-P416 VanDerWaalsContact C-CD 3.49Å; K414-P416 WeakPolarHBondContact O-CD 3.41Å; P416-R418 VanDerWaalsContact C-N 3.3Å; P416-R418 PolarHBondContact O-N 3.38Å; P416-R420 PolarHBondContact O-NH1 3.1Å
417	E	89.9	Confident	91.9	Very high	174 Å²	174	74.8 Å²	74.8	81%	0.813	36%	0.364	S	S	*	.	T	Hydrogen-bonded Turn	trans	-79.4	-4.6	-175.7	-61.3	-57	147.2	0	0	114.4	E415	E415-E417 VanDerWaalsContact C-N 3.33Å; E415-E417 PolarHBondContact O-N 2.8Å
418	R	90.3	Very high	91.9	Very high	54 Å²	54	78.2 Å²	78.2	20%	0.204	38%	0.379	C	S	.	.	S	Bend	trans	-60.5	131.7	178.4	-169.3	173.9	-175.4	143.6	0.6	109.5	T104 E117 E415 P416 R420	T104-R418 HydrophobicContact CG2-CG 4.19Å; E117-R418 IonicContact OE1-CZ 3.16Å; E117-R418 IonicContact OE1-NH1 2.84Å; E117-R418 PolarHBondContact OE1-NH1 3.44Å; E117-R418 IonicContact OE1-NH2 3.74Å; E117-R418 PolarHBondContact OE1-NH2 3.48Å; E415-R418 HydrophobicContact CB-CB 4.33Å; E415-R418 IonicContact OE2-CZ 2.93Å; E415-R418 IonicContact OE2-NH1 3.73Å; E415-R418 PolarHBondContact OE2-NH1 3.34Å; P416-R418 VanDerWaalsContact C-N 3.3Å; P416-R418 PolarHBondContact O-N 3.38Å; R418-R420 PolarHBondContact O-N 2.84Å
419	P	87.9	Confident	91.9	Very high	110 Å²	110	78 Å²	78	71%	0.714	38%	0.378	S	S	*	.			trans	-62.9	123.4	179.3	25.6	-33.6	0	0	0	109.7
420	R	90.8	Very high	91.9	Very high	38 Å²	38	79.6 Å²	79.6	14%	0.143	39%	0.386	C	S	.	.			trans	-121.6	95.7	178.2	-66.6	-176.2	-176.1	100.3	9.1	108.9	T104 L411 R412 E415 P416 R418 L422	T104-R420 HydrophobicContact CG2-CG 4.03Å; L411-R420 PolarHBondContact O-NH2 3.41Å; R412-R420 VanDerWaalsContact CA-NH2 3.3Å; E415-R420 PolarHBondContact O-NH2 3.49Å; P416-R420 PolarHBondContact O-NH1 3.1Å; R418-R420 PolarHBondContact O-N 2.84Å; R420-L422 VanDerWaalsContact C-N 3.26Å; R420-L422 PolarHBondContact O-N 3.26Å
421	P	88.7	Confident	91.9	Very high	60 Å²	60	78.5 Å²	78.5	39%	0.39	39%	0.387	S	S	.	.	S	Bend	trans	-59	-38.9	-179.8	-25.3	35	0	0	0	112.5	E264	E264-P421 HydrophobicContact CB-CB 3.89Å; E264-P421 HydrophobicContact CB-CG 4.5Å; E264-P421 HydrophobicContact CG-CB 3.7Å; E264-P421 HydrophobicContact CG-CG 3.76Å
422	L	88.9	Confident	92	Very high	40 Å²	40	78.2 Å²	78.2	21%	0.209	39%	0.385	C	S	.	.	S	Bend	trans	-107.2	125.7	167.8	-172.8	75.5	0	0	0	109.1	A99 E100 T103 P268 R420	A99-L422 HydrophobicContact CB-CD2 3.81Å; E100-L422 HydrophobicContact CB-CD2 4.25Å; E100-L422 WeakPolarHBondContact CG-O 3.35Å; T103-L422 HydrophobicContact CG2-CB 4.41Å; T103-L422 WeakPolarHBondContact OG1-CB 3.41Å; P268-L422 HydrophobicContact CB-CD1 4.41Å; P268-L422 HydrophobicContact CB-CD2 4.07Å; P268-L422 HydrophobicContact CG-CD1 4.37Å; P268-L422 HydrophobicContact CG-CD2 3.9Å; R420-L422 VanDerWaalsContact C-N 3.26Å; R420-L422 PolarHBondContact O-N 3.26Å
423	K	89.6	Confident	92.1	Very high	150 Å²	150	77.5 Å²	77.5	65%	0.652	39%	0.385	S	S	*	.			trans	-128.1	107.5	175	-172	178.7	-179.2	177	0	110
424	L	90.5	Very high	92.2	Very high	28 Å²	28	72.8 Å²	72.8	15%	0.147	37%	0.374	C	S	.	.			trans	-80.3	158.9	176.6	-65.4	170.3	0	0	0	111.9	L96 E100 R412	L96-L424 HydrophobicContact CB-CD1 3.8Å; L96-L424 WeakPolarHBondContact O-CD1 3.27Å; E100-L424 HydrophobicContact CB-CD1 4.3Å; E100-L424 WeakPolarHBondContact OE2-CB 3.36Å; E100-L424 PolarHBondContact OE2-N 3.22Å; R412-L424 PolarHBondContact NH1-O 3.36Å; R412-L424 PolarHBondContact NH2-O 3.47Å
425	S	93.6	Very high	92.1	Very high	73 Å²	73	69.3 Å²	69.3	51%	0.51	37%	0.365	S	S	.	.			trans	-60.4	140.4	165.9	179.8	0	0	0	0	109.7	F427 F428 P429	S425-F427 PolarHBondContact O-N 2.89Å; S425-F427 VanDerWaalsContact O-N 3.1Å; S425-F427 PolarHBondContact OG-N 3.09Å; S425-F428 PolarHBondContact O-N 3.15Å; S425-P429 WeakPolarHBondContact O-CD 3.39Å
426	V	93.3	Very high	92.1	Very high	68 Å²	68	66.1 Å²	66.1	41%	0.412	35%	0.35	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.6	-20.2	178.3	-176.7	0	0	0	0	111.7	L409 F428 P429 I430	L409-V426 HydrophobicContact CD2-CG1 3.9Å; V426-F428 VanDerWaalsContact C-N 3.35Å; V426-F428 PolarHBondContact O-N 3.03Å; V426-P429 VanDerWaalsContact O-CD 3.25Å; V426-P429 WeakPolarHBondContact O-CD 3.28Å; V426-P429 VanDerWaalsContact O-CG 3.31Å; V426-P429 WeakPolarHBondContact O-CG 3.18Å; V426-I430 HydrophobicContact CG1-CD1 3.61Å; V426-I430 HydrophobicContact CG1-CG1 4Å; V426-I430 WeakPolarHBondContact O-CG1 3.39Å; V426-I430 PolarHBondContact O-N 2.9Å
427	F	94.1	Very high	92.2	Very high	133 Å²	133	66.1 Å²	66.1	58%	0.583	35%	0.349	S	S	*	.	H	α-helix	trans	-53.3	-47.8	174.5	176.7	-102.4	0	0	0	112.9	S425 I430 V431	S425-F427 PolarHBondContact O-N 2.89Å; S425-F427 VanDerWaalsContact O-N 3.1Å; S425-F427 PolarHBondContact OG-N 3.09Å; F427-I430 PolarHBondContact O-N 2.91Å; F427-V431 HydrophobicContact CD1-CG2 4.35Å; F427-V431 HydrophobicContact CD2-CG2 4.09Å; F427-V431 HydrophobicContact CE1-CG2 3.99Å; F427-V431 HydrophobicContact CE2-CG2 3.71Å; F427-V431 HydrophobicContact CG-CG2 4.4Å; F427-V431 HydrophobicContact CZ-CG2 3.65Å; F427-V431 VanDerWaalsContact O-CG2 3.31Å; F427-V431 WeakPolarHBondContact O-CG2 3.47Å; F427-V431 PolarHBondContact O-N 2.87Å
428	F	94.1	Very high	92.2	Very high	72 Å²	72	61.5 Å²	61.5	32%	0.316	33%	0.326	S	S	.	.	H	α-helix	trans	-60.9	-53.8	-177.2	-66.4	-75.4	0	0	0	113.7	V93 S425 V426 I430 V431 F432	V93-F428 HydrophobicContact CG1-CB 4.12Å; V93-F428 HydrophobicContact CG1-CD1 4.18Å; V93-F428 WeakPolarHBondContact CG1-O 3.2Å; V93-F428 HydrophobicContact CG2-CD1 4.36Å; S425-F428 PolarHBondContact O-N 3.15Å; V426-F428 VanDerWaalsContact C-N 3.35Å; V426-F428 PolarHBondContact O-N 3.03Å; F428-I430 VanDerWaalsContact C-N 3.32Å; F428-I430 PolarHBondContact O-N 3.18Å; F428-V431 PolarHBondContact O-N 3.29Å; F428-F432 WeakPolarHBondContact O-CB 3.44Å; F428-F432 PolarHBondContact O-N 2.71Å
429	P	94.8	Very high	92.1	Very high	0 Å²	0	59 Å²	59	0%	0	32%	0.317	C	S	.	.	H	α-helix	trans	-64.7	-33	177.9	22.9	-32.2	0	0	0	112.8	C97 V405 L409 S425 V426 F432 C433	C97-P429 VanDerWaalsContact SG-CA 3.58Å; V405-P429 HydrophobicContact CG1-CB 3.46Å; V405-P429 VanDerWaalsContact CG1-CB 3.46Å; L409-P429 HydrophobicContact CD1-CB 4.45Å; L409-P429 HydrophobicContact CD2-CB 3.97Å; L409-P429 HydrophobicContact CD2-CG 3.78Å; L409-P429 HydrophobicContact CG-CB 4.14Å; L409-P429 HydrophobicContact CG-CG 4.49Å; S425-P429 WeakPolarHBondContact O-CD 3.39Å; V426-P429 VanDerWaalsContact O-CD 3.25Å; V426-P429 WeakPolarHBondContact O-CD 3.28Å; V426-P429 VanDerWaalsContact O-CG 3.31Å; V426-P429 WeakPolarHBondContact O-CG 3.18Å; P429-F432 PolarHBondContact O-N 3.44Å; P429-C433 WeakPolarHBondContact O-CB 3.44Å; P429-C433 PolarHBondContact O-N 2.68Å; P429-C433 PolarHBondContact O-SG 2.79Å
430	I	95.2	Very high	92.1	Very high	79 Å²	79	54.7 Å²	54.7	41%	0.405	29%	0.288	S	S	.	.	H	α-helix	trans	-64.3	-49.2	174.8	-70.7	176.4	0	0	0	110.9	L409 V426 F427 F428 F432 C433 I434	L409-I430 HydrophobicContact CD1-CG1 4.33Å; V426-I430 HydrophobicContact CG1-CD1 3.61Å; V426-I430 HydrophobicContact CG1-CG1 4Å; V426-I430 WeakPolarHBondContact O-CG1 3.39Å; V426-I430 PolarHBondContact O-N 2.9Å; F427-I430 PolarHBondContact O-N 2.91Å; F428-I430 VanDerWaalsContact C-N 3.32Å; F428-I430 PolarHBondContact O-N 3.18Å; I430-F432 VanDerWaalsContact C-N 3.29Å; I430-F432 PolarHBondContact O-N 2.86Å; I430-C433 PolarHBondContact O-N 3.5Å; I430-I434 HydrophobicContact CG2-CD1 3.81Å; I430-I434 HydrophobicContact CG2-CG1 4.46Å; I430-I434 WeakPolarHBondContact O-CG1 3.45Å; I430-I434 PolarHBondContact O-N 3.43Å
431	V	94.7	Very high	92.1	Very high	48 Å²	48	56.8 Å²	56.8	29%	0.291	30%	0.302	S	S	.	.	H	α-helix	trans	-58.8	-45.1	177.9	169.9	0	0	0	0	110.3	F427 F428 C433 I434 C435	F427-V431 HydrophobicContact CD1-CG2 4.35Å; F427-V431 HydrophobicContact CD2-CG2 4.09Å; F427-V431 HydrophobicContact CE1-CG2 3.99Å; F427-V431 HydrophobicContact CE2-CG2 3.71Å; F427-V431 HydrophobicContact CG-CG2 4.4Å; F427-V431 HydrophobicContact CZ-CG2 3.65Å; F427-V431 VanDerWaalsContact O-CG2 3.31Å; F427-V431 WeakPolarHBondContact O-CG2 3.47Å; F427-V431 PolarHBondContact O-N 2.87Å; F428-V431 PolarHBondContact O-N 3.29Å; V431-C433 PolarHBondContact O-N 3.09Å; V431-I434 PolarHBondContact O-N 3.41Å; V431-C435 WeakPolarHBondContact O-CB 3.45Å; V431-C435 PolarHBondContact O-N 3.42Å; V431-C435 PolarHBondContact O-SG 3.24Å; V431-C435 VanDerWaalsContact O-SG 3.41Å
432	F	94.6	Very high	92	Very high	1 Å²	1	55.1 Å²	55.1	0%	0.004	29%	0.29	C	S	.	.	H	α-helix	trans	-61.2	-43.2	177.5	-171.5	-95	0	0	0	112.7	F90 V93 G94 W398 V401 V405 F428 P429 I430 C435 S436	F90-F432 HydrophobicContact CD1-CE2 4.21Å; F90-F432 HydrophobicContact CD2-CD2 4.03Å; F90-F432 HydrophobicContact CD2-CE2 4.09Å; F90-F432 AromaticContact CE1-CE2 3.66Å; F90-F432 HydrophobicContact CE1-CE2 3.66Å; F90-F432 HydrophobicContact CE1-CZ 4.14Å; F90-F432 AromaticContact CE2-CD2 3.53Å; F90-F432 HydrophobicContact CE2-CD2 3.53Å; F90-F432 AromaticContact CE2-CE2 3.45Å; F90-F432 HydrophobicContact CE2-CE2 3.45Å; F90-F432 VanDerWaalsContact CE2-CE2 3.45Å; F90-F432 HydrophobicContact CE2-CG 4.31Å; F90-F432 HydrophobicContact CE2-CZ 4.18Å; F90-F432 HydrophobicContact CG-CE2 4.44Å; F90-F432 AromaticContact CZ-CD2 3.84Å; F90-F432 HydrophobicContact CZ-CD2 3.84Å; F90-F432 AromaticContact CZ-CE2 3.24Å; F90-F432 HydrophobicContact CZ-CE2 3.24Å; F90-F432 AromaticContact CZ-CZ 3.63Å; F90-F432 HydrophobicContact CZ-CZ 3.63Å; V93-F432 HydrophobicContact CG1-CB 4.01Å; V93-F432 HydrophobicContact CG1-CD2 4.4Å; G94-F432 VanDerWaalsContact CA-CD2 3.4Å; W398-F432 HydrophobicContact CE3-CZ 4.31Å; W398-F432 HydrophobicContact CZ3-CE2 4.5Å; W398-F432 HydrophobicContact CZ3-CZ 4.13Å; V401-F432 HydrophobicContact CG1-CE1 3.82Å; V401-F432 HydrophobicContact CG1-CZ 3.63Å; V405-F432 HydrophobicContact CB-CD1 3.97Å; V405-F432 HydrophobicContact CB-CE1 4.41Å; V405-F432 HydrophobicContact CG1-CD1 4.11Å; V405-F432 HydrophobicContact CG2-CD1 3.63Å; V405-F432 HydrophobicContact CG2-CE1 3.76Å; F428-F432 WeakPolarHBondContact O-CB 3.44Å; F428-F432 PolarHBondContact O-N 2.71Å; P429-F432 PolarHBondContact O-N 3.44Å; I430-F432 VanDerWaalsContact C-N 3.29Å; I430-F432 PolarHBondContact O-N 2.86Å; F432-C435 PolarHBondContact O-N 3.04Å; F432-S436 VanDerWaalsContact CE1-OG 3.27Å; F432-S436 WeakPolarHBondContact CE1-OG 3.29Å; F432-S436 WeakPolarHBondContact O-CB 3.26Å; F432-S436 PolarHBondContact O-N 3.41Å; F432-S436 PolarHBondContact O-OG 2.96Å
433	C	94.7	Very high	91.8	Very high	19 Å²	19	53.2 Å²	53.2	13%	0.128	28%	0.28	C	S	.	.	H	α-helix	trans	-62.2	-43.9	176	-74.1	0	0	0	0	111.9	P429 I430 V431 S436 V437	P429-C433 WeakPolarHBondContact O-CB 3.44Å; P429-C433 PolarHBondContact O-N 2.68Å; P429-C433 PolarHBondContact O-SG 2.79Å; I430-C433 PolarHBondContact O-N 3.5Å; V431-C433 PolarHBondContact O-N 3.09Å; C433-S436 PolarHBondContact O-N 3.25Å; C433-V437 VanDerWaalsContact O-CG2 3.3Å; C433-V437 WeakPolarHBondContact O-CG2 3.49Å; C433-V437 PolarHBondContact O-N 3.47Å
434	I	94.2	Very high	91.6	Very high	110 Å²	110	48.4 Å²	48.4	56%	0.564	26%	0.261	S	S	*	.	H	α-helix	trans	-61	-47.5	177	-67.9	167.3	0	0	0	110.5	I430 V431 S436 V437 F438	I430-I434 HydrophobicContact CG2-CD1 3.81Å; I430-I434 HydrophobicContact CG2-CG1 4.46Å; I430-I434 WeakPolarHBondContact O-CG1 3.45Å; I430-I434 PolarHBondContact O-N 3.43Å; V431-I434 PolarHBondContact O-N 3.41Å; I434-S436 VanDerWaalsContact C-N 3.34Å; I434-S436 PolarHBondContact O-N 2.9Å; I434-V437 PolarHBondContact O-N 2.98Å; I434-F438 PolarHBondContact O-N 3.49Å
435	C	92.2	Very high	91.5	Very high	47 Å²	47	54.8 Å²	54.8	32%	0.318	29%	0.288	S	S	.	.	H	α-helix	trans	-64.4	-38	177	-70.2	0	0	0	0	112.1	F90 V431 F432 F438 L439	F90-C435 HydrophobicContact CD2-CB 3.58Å; F90-C435 HydrophobicContact CE2-CB 3.35Å; F90-C435 HydrophobicContact CZ-CB 4.5Å; V431-C435 WeakPolarHBondContact O-CB 3.45Å; V431-C435 PolarHBondContact O-N 3.42Å; V431-C435 PolarHBondContact O-SG 3.24Å; V431-C435 VanDerWaalsContact O-SG 3.41Å; F432-C435 PolarHBondContact O-N 3.04Å; C435-F438 WeakPolarHBondContact O-CB 3.18Å; C435-F438 PolarHBondContact O-N 2.8Å; C435-L439 WeakPolarHBondContact O-CG 3.5Å; C435-L439 PolarHBondContact O-N 3.06Å
436	S	91.9	Very high	91	Very high	6 Å²	6	54.3 Å²	54.3	4%	0.042	28%	0.282	C	S	.	.	H	α-helix	trans	-64.7	-39.5	175.2	-58.8	0	0	0	0	111.7	F432 C433 I434 L439 V440	F432-S436 VanDerWaalsContact CE1-OG 3.27Å; F432-S436 WeakPolarHBondContact CE1-OG 3.29Å; F432-S436 WeakPolarHBondContact O-CB 3.26Å; F432-S436 PolarHBondContact O-N 3.41Å; F432-S436 PolarHBondContact O-OG 2.96Å; C433-S436 PolarHBondContact O-N 3.25Å; I434-S436 VanDerWaalsContact C-N 3.34Å; I434-S436 PolarHBondContact O-N 2.9Å; S436-L439 PolarHBondContact O-N 3.23Å; S436-V440 WeakPolarHBondContact O-CG2 3.27Å; S436-V440 PolarHBondContact O-N 2.65Å
437	V	92.1	Very high	90.5	Very high	78 Å²	78	52.4 Å²	52.4	47%	0.473	27%	0.27	S	S	.	.	H	α-helix	trans	-62.5	-43.7	173.7	168.5	0	0	0	0	110.7	C433 I434 L439 V440 I441	C433-V437 VanDerWaalsContact O-CG2 3.3Å; C433-V437 WeakPolarHBondContact O-CG2 3.49Å; C433-V437 PolarHBondContact O-N 3.47Å; I434-V437 PolarHBondContact O-N 2.98Å; V437-L439 VanDerWaalsContact C-N 3.34Å; V437-L439 PolarHBondContact O-N 3.26Å; V437-V440 PolarHBondContact O-N 3.36Å; V437-V440 VanDerWaalsContact O-N 3.16Å; V437-I441 HydrophobicContact CG1-CD1 3.38Å; V437-I441 HydrophobicContact CG1-CG1 4.04Å; V437-I441 WeakPolarHBondContact O-CB 3.47Å; V437-I441 VanDerWaalsContact O-CG1 3.31Å; V437-I441 WeakPolarHBondContact O-CG1 3.45Å; V437-I441 PolarHBondContact O-N 3.23Å
438	F	90.7	Very high	90.1	Very high	78 Å²	78	49.1 Å²	49.1	34%	0.342	26%	0.261	S	S	.	.	H	α-helix	trans	-58	-46.3	173.6	171.5	-92.5	0	0	0	111.9	I434 C435 V440 I441 V442	I434-F438 PolarHBondContact O-N 3.49Å; C435-F438 WeakPolarHBondContact O-CB 3.18Å; C435-F438 PolarHBondContact O-N 2.8Å; F438-V440 PolarHBondContact O-N 2.97Å; F438-I441 PolarHBondContact O-N 3.48Å; F438-V442 HydrophobicContact CD2-CG2 3.63Å; F438-V442 HydrophobicContact CE2-CG2 3.44Å; F438-V442 VanDerWaalsContact CE2-CG2 3.44Å; F438-V442 HydrophobicContact CG-CG2 4.29Å; F438-V442 HydrophobicContact CZ-CG2 3.94Å; F438-V442 PolarHBondContact O-N 3.19Å; F438-V442 VanDerWaalsContact O-N 3.07Å
439	L	87.7	Confident	89.8	Confident	1 Å²	1	51.7 Å²	51.7	1%	0.005	28%	0.277	C	S	.	.	H	α-helix	trans	-63	-24.2	177.7	-73.6	175.5	0	0	0	113.2	F90 L240 Y241 L244 W398 C435 S436 V437 P443	F90-L439 HydrophobicContact CD1-CD1 4.48Å; F90-L439 HydrophobicContact CE1-CD1 3.68Å; F90-L439 HydrophobicContact CE2-CD1 4.21Å; F90-L439 HydrophobicContact CZ-CD1 3.51Å; L240-L439 HydrophobicContact CD2-CD2 3.69Å; L240-L439 HydrophobicContact CG-CD2 4.05Å; Y241-L439 HydrophobicContact CD1-CD2 3.98Å; Y241-L439 HydrophobicContact CE1-CB 4.08Å; Y241-L439 HydrophobicContact CE1-CD2 3.86Å; Y241-L439 VanDerWaalsContact CE1-O 3.29Å; Y241-L439 WeakPolarHBondContact CE1-O 3.26Å; Y241-L439 VanDerWaalsContact CZ-O 3.24Å; Y241-L439 PolarHBondContact OH-O 3.45Å; L244-L439 HydrophobicContact CD1-CD1 3.49Å; L244-L439 VanDerWaalsContact CD1-CD1 3.49Å; L244-L439 HydrophobicContact CD1-CD2 3.96Å; L244-L439 HydrophobicContact CD1-CG 4.4Å; W398-L439 HydrophobicContact CB-CD1 4.46Å; W398-L439 HydrophobicContact CG-CD1 4.26Å; C435-L439 WeakPolarHBondContact O-CG 3.5Å; C435-L439 PolarHBondContact O-N 3.06Å; S436-L439 PolarHBondContact O-N 3.23Å; V437-L439 VanDerWaalsContact C-N 3.34Å; V437-L439 PolarHBondContact O-N 3.26Å; L439-P443 WeakPolarHBondContact O-CD 3.41Å; L439-P443 VanDerWaalsContact O-CG 3.27Å; L439-P443 WeakPolarHBondContact O-CG 3.48Å
440	V	88.4	Confident	89.3	Confident	20 Å²	20	52.6 Å²	52.6	12%	0.121	28%	0.281	C	S	.	.	H	α-helix	trans	-91.6	-40.6	177.2	172.5	0	0	0	0	111.2	F395 F399 S436 V437 F438 L444	F395-V440 HydrophobicContact CE2-CB 4.48Å; F395-V440 HydrophobicContact CE2-CG1 3.75Å; F395-V440 HydrophobicContact CZ-CG1 4.06Å; F399-V440 HydrophobicContact CB-CG2 3.93Å; F399-V440 HydrophobicContact CD2-CG1 4.26Å; F399-V440 HydrophobicContact CD2-CG2 4.17Å; S436-V440 WeakPolarHBondContact O-CG2 3.27Å; S436-V440 PolarHBondContact O-N 2.65Å; V437-V440 PolarHBondContact O-N 3.36Å; V437-V440 VanDerWaalsContact O-N 3.16Å; F438-V440 PolarHBondContact O-N 2.97Å; V440-L444 WeakPolarHBondContact O-CG 3.46Å
441	I	89.6	Confident	88.8	Confident	82 Å²	82	49 Å²	49	42%	0.421	26%	0.263	S	S	.	.	H	α-helix	trans	-74.7	-46.3	-173.2	-69	-178.2	0	0	0	112.1	V437 F438 L444 F445	V437-I441 HydrophobicContact CG1-CD1 3.38Å; V437-I441 HydrophobicContact CG1-CG1 4.04Å; V437-I441 WeakPolarHBondContact O-CB 3.47Å; V437-I441 VanDerWaalsContact O-CG1 3.31Å; V437-I441 WeakPolarHBondContact O-CG1 3.45Å; V437-I441 PolarHBondContact O-N 3.23Å; F438-I441 PolarHBondContact O-N 3.48Å; I441-L444 WeakPolarHBondContact O-CB 3.19Å; I441-L444 PolarHBondContact O-N 3.38Å; I441-F445 HydrophobicContact CG2-CD2 4.3Å; I441-F445 HydrophobicContact CG2-CE2 3.71Å; I441-F445 WeakPolarHBondContact O-CD2 3.39Å
442	V	87.6	Confident	88.5	Confident	24 Å²	24	51.3 Å²	51.3	15%	0.145	27%	0.273	C	S	.	.	H	α-helix	trans	-62.6	-44.8	-175.4	177.8	0	0	0	0	111.6	S237 F438 L444 F445 T446	S237-V442 VanDerWaalsContact OG-CG1 3.31Å; S237-V442 WeakPolarHBondContact OG-CG1 3.48Å; F438-V442 HydrophobicContact CD2-CG2 3.63Å; F438-V442 HydrophobicContact CE2-CG2 3.44Å; F438-V442 VanDerWaalsContact CE2-CG2 3.44Å; F438-V442 HydrophobicContact CG-CG2 4.29Å; F438-V442 HydrophobicContact CZ-CG2 3.94Å; F438-V442 PolarHBondContact O-N 3.19Å; F438-V442 VanDerWaalsContact O-N 3.07Å; V442-L444 VanDerWaalsContact C-N 3.25Å; V442-L444 PolarHBondContact O-N 2.91Å; V442-F445 PolarHBondContact O-N 3.02Å; V442-T446 HydrophobicContact CG1-CG2 4.1Å; V442-T446 PolarHBondContact O-N 3.44Å; V442-T446 VanDerWaalsContact O-N 3.13Å; V442-T446 PolarHBondContact O-OG1 3.34Å
443	P	83.6	Confident	88.2	Confident	1 Å²	1	54.5 Å²	54.5	1%	0.006	29%	0.29	C	S	.	.	H	α-helix	trans	-63.8	-24.2	177.1	-30.3	44.5	0	0	0	114.8	Y241 L439 F445 T446 D447 S451	Y241-P443 HydrophobicContact CE1-CG 4Å; Y241-P443 HydrophobicContact CE2-CB 4.04Å; Y241-P443 HydrophobicContact CE2-CG 3.85Å; Y241-P443 WeakPolarHBondContact OH-CG 3.42Å; L439-P443 WeakPolarHBondContact O-CD 3.41Å; L439-P443 VanDerWaalsContact O-CG 3.27Å; L439-P443 WeakPolarHBondContact O-CG 3.48Å; P443-F445 PolarHBondContact O-N 3.37Å; P443-T446 WeakPolarHBondContact CA-OG1 3.41Å; P443-T446 PolarHBondContact O-N 2.91Å; P443-D447 CarbonylContact O-C 3.16Å; P443-D447 WeakPolarHBondContact O-CA 3.34Å; P443-D447 PolarHBondContact O-N 3.19Å; P443-S451 PolarHBondContact O-OG 3.13Å
444	L	86.9	Confident	87.7	Confident	48 Å²	48	53.8 Å²	53.8	25%	0.251	29%	0.286	S	S	.	.	H	α-helix	trans	-62.1	-27.8	172.2	-74	166.2	0	0	0	112.6	F395 V440 I441 V442 T448 I455	F395-L444 HydrophobicContact CE2-CD2 4.15Å; F395-L444 HydrophobicContact CE2-CG 4.11Å; F395-L444 HydrophobicContact CZ-CD2 4.25Å; V440-L444 WeakPolarHBondContact O-CG 3.46Å; I441-L444 WeakPolarHBondContact O-CB 3.19Å; I441-L444 PolarHBondContact O-N 3.38Å; V442-L444 VanDerWaalsContact C-N 3.25Å; V442-L444 PolarHBondContact O-N 2.91Å; L444-T448 WeakPolarHBondContact O-CA 3.43Å; L444-T448 VanDerWaalsContact O-CB 3.29Å; L444-T448 WeakPolarHBondContact O-CB 3.3Å; L444-T448 WeakPolarHBondContact O-CG2 3.37Å; L444-T448 PolarHBondContact O-OG1 3Å; L444-I455 HydrophobicContact CD2-CD1 3.63Å
445	F	87.2	Confident	87.5	Confident	162 Å²	162	51.4 Å²	51.4	71%	0.711	27%	0.273	S	S	*	.	H	α-helix	trans	-94.7	-29.8	177.9	-61.1	-71.5	0	0	0	113	I441 V442 P443	I441-F445 HydrophobicContact CG2-CD2 4.3Å; I441-F445 HydrophobicContact CG2-CE2 3.71Å; I441-F445 WeakPolarHBondContact O-CD2 3.39Å; V442-F445 PolarHBondContact O-N 3.02Å; P443-F445 PolarHBondContact O-N 3.37Å
446	T	83.3	Confident	87.4	Confident	63 Å²	63	51.9 Å²	51.9	39%	0.387	28%	0.281	S	S	.	.	H	α-helix	trans	-94.9	-33.9	-174.1	59.1	0	0	0	0	112.7	V442 P443	V442-T446 HydrophobicContact CG1-CG2 4.1Å; V442-T446 PolarHBondContact O-N 3.44Å; V442-T446 VanDerWaalsContact O-N 3.13Å; V442-T446 PolarHBondContact O-OG1 3.34Å; P443-T446 WeakPolarHBondContact CA-OG1 3.41Å; P443-T446 PolarHBondContact O-N 2.91Å
447	D	82.5	Confident	87.3	Confident	28 Å²	28	53.5 Å²	53.5	15%	0.15	29%	0.288	C	S	.	.	S	Bend	trans	-130	58.2	176.2	-165.7	4.6	0	0	0	110.4	L238 N391 P443 I449 N450 S451	L238-D447 HydrophobicContact CD2-CB 4.43Å; N391-D447 PolarHBondContact ND2-OD2 3.38Å; P443-D447 CarbonylContact O-C 3.16Å; P443-D447 WeakPolarHBondContact O-CA 3.34Å; P443-D447 PolarHBondContact O-N 3.19Å; D447-I449 PolarHBondContact O-N 3.35Å; D447-N450 PolarHBondContact O-N 2.99Å; D447-N450 WeakPolarHBondContact OD1-CB 3.32Å; D447-N450 VanDerWaalsContact OD1-CG 3.32Å; D447-N450 PolarHBondContact OD1-ND2 3.25Å; D447-N450 WeakPolarHBondContact OD2-CB 3.41Å; D447-N450 PolarHBondContact OD2-ND2 3.11Å; D447-S451 WeakPolarHBondContact O-CB 3.31Å; D447-S451 PolarHBondContact O-N 3.36Å; D447-S451 PolarHBondContact O-OG 3.13Å
448	T	87.1	Confident	87.2	Confident	64 Å²	64	50.7 Å²	50.7	39%	0.393	27%	0.273	S	S	.	.	H	α-helix	trans	-58.8	-43.9	-170.5	-53.2	0	0	0	0	112.7	L444 N450 S451 L452	L444-T448 WeakPolarHBondContact O-CA 3.43Å; L444-T448 VanDerWaalsContact O-CB 3.29Å; L444-T448 WeakPolarHBondContact O-CB 3.3Å; L444-T448 WeakPolarHBondContact O-CG2 3.37Å; L444-T448 PolarHBondContact O-OG1 3Å; T448-N450 PolarHBondContact O-N 3.41Å; T448-S451 PolarHBondContact O-N 3.47Å; T448-L452 HydrophobicContact CG2-CD1 3.75Å; T448-L452 HydrophobicContact CG2-CG 4.14Å; T448-L452 VanDerWaalsContact O-CB 3.29Å; T448-L452 WeakPolarHBondContact O-CB 3.4Å; T448-L452 WeakPolarHBondContact O-CG 3.11Å; T448-L452 PolarHBondContact O-N 3.01Å
449	I	87.4	Confident	87.2	Confident	127 Å²	127	52.1 Å²	52.1	65%	0.651	28%	0.284	S	S	*	.	H	α-helix	trans	-62.2	-48.4	-177.1	-64.2	175.5	0	0	0	109.4	D447 S451 L452 I453	D447-I449 PolarHBondContact O-N 3.35Å; I449-S451 PolarHBondContact O-N 3.35Å; I449-L452 PolarHBondContact O-N 3.04Å; I449-I453 HydrophobicContact CG2-CD1 3.96Å; I449-I453 VanDerWaalsContact O-CG1 3.32Å; I449-I453 WeakPolarHBondContact O-CG1 3.44Å; I449-I453 PolarHBondContact O-N 3.43Å
450	N	84	Confident	87.5	Confident	18 Å²	18	54.2 Å²	54.2	10%	0.096	30%	0.299	C	S	.	.	H	α-helix	trans	-68.8	-39.7	-175.9	-69.3	-26.7	0	0	0	112.5	Y392 D447 T448 I453 G454	Y392-N450 HydrophobicContact CD1-CB 3.84Å; Y392-N450 HydrophobicContact CE1-CB 3.34Å; Y392-N450 WeakPolarHBondContact CE1-OD1 3.44Å; Y392-N450 VanDerWaalsContact CZ-OD1 3.27Å; Y392-N450 PolarHBondContact OH-OD1 2.99Å; D447-N450 PolarHBondContact O-N 2.99Å; D447-N450 WeakPolarHBondContact OD1-CB 3.32Å; D447-N450 VanDerWaalsContact OD1-CG 3.32Å; D447-N450 PolarHBondContact OD1-ND2 3.25Å; D447-N450 WeakPolarHBondContact OD2-CB 3.41Å; D447-N450 PolarHBondContact OD2-ND2 3.11Å; T448-N450 PolarHBondContact O-N 3.41Å; N450-I453 PolarHBondContact O-N 3.49Å; N450-G454 PolarHBondContact O-N 2.62Å; N450-G454 VanDerWaalsContact O-N 3.11Å
451	S	85.4	Confident	87.6	Confident	4 Å²	4	53.3 Å²	53.3	3%	0.028	29%	0.293	C	S	.	.	H	α-helix	trans	-63	-41.9	174.9	-55.7	0	0	0	0	112.1	P443 D447 T448 I449 G454 I455	P443-S451 PolarHBondContact O-OG 3.13Å; D447-S451 WeakPolarHBondContact O-CB 3.31Å; D447-S451 PolarHBondContact O-N 3.36Å; D447-S451 PolarHBondContact O-OG 3.13Å; T448-S451 PolarHBondContact O-N 3.47Å; I449-S451 PolarHBondContact O-N 3.35Å; S451-G454 PolarHBondContact O-N 2.67Å; S451-I455 WeakPolarHBondContact O-CG1 3.46Å; S451-I455 PolarHBondContact O-N 3.23Å
452	L	88.4	Confident	87.7	Confident	96 Å²	96	51.3 Å²	51.3	50%	0.503	29%	0.285	S	S	.	.	H	α-helix	trans	-65.5	-37.7	177.3	-75.7	176.1	0	0	0	112.4	T448 I449 G454 I455 A456	T448-L452 HydrophobicContact CG2-CD1 3.75Å; T448-L452 HydrophobicContact CG2-CG 4.14Å; T448-L452 VanDerWaalsContact O-CB 3.29Å; T448-L452 WeakPolarHBondContact O-CB 3.4Å; T448-L452 WeakPolarHBondContact O-CG 3.11Å; T448-L452 PolarHBondContact O-N 3.01Å; I449-L452 PolarHBondContact O-N 3.04Å; L452-G454 VanDerWaalsContact C-N 3.34Å; L452-I455 PolarHBondContact O-N 3.18Å; L452-A456 VanDerWaalsContact O-CB 3.31Å; L452-A456 WeakPolarHBondContact O-CB 3.48Å; L452-A456 PolarHBondContact O-N 3.28Å
453	I	86.5	Confident	87.9	Confident	69 Å²	69	53.7 Å²	53.7	35%	0.354	30%	0.301	S	S	.	.	H	α-helix	trans	-61.3	-45.8	173.6	-68.3	165.1	0	0	0	110	I449 N450 I455 A456 I457	I449-I453 HydrophobicContact CG2-CD1 3.96Å; I449-I453 VanDerWaalsContact O-CG1 3.32Å; I449-I453 WeakPolarHBondContact O-CG1 3.44Å; I449-I453 PolarHBondContact O-N 3.43Å; N450-I453 PolarHBondContact O-N 3.49Å; I453-I455 VanDerWaalsContact C-N 3.35Å; I453-I455 PolarHBondContact O-N 2.86Å; I453-A456 PolarHBondContact O-N 3.2Å; I453-I457 HydrophobicContact CG2-CD1 3.89Å; I453-I457 HydrophobicContact CG2-CG1 4.47Å; I453-I457 WeakPolarHBondContact O-CG1 3.33Å; I453-I457 PolarHBondContact O-N 3.48Å
454	G	85.2	Confident	88.1	Confident	4 Å²	4	59 Å²	59	4%	0.041	32%	0.324	C	S	.	.	H	α-helix	trans	-58.4	-44.2	176	0	0	0	0	0	112.8	N450 S451 L452 I457 A458	N450-G454 PolarHBondContact O-N 2.62Å; N450-G454 VanDerWaalsContact O-N 3.11Å; S451-G454 PolarHBondContact O-N 2.67Å; L452-G454 VanDerWaalsContact C-N 3.34Å; G454-I457 PolarHBondContact O-N 2.97Å; G454-A458 PolarHBondContact O-N 3.13Å
455	I	89.5	Confident	88.1	Confident	59 Å²	59	58.2 Å²	58.2	30%	0.303	32%	0.318	S	S	.	.	H	α-helix	trans	-64.1	-43.9	175	-67.7	168.1	0	0	0	111.1	F395 L444 S451 L452 I453 I457 A458 L459	F395-I455 HydrophobicContact CE1-CG1 3.87Å; F395-I455 HydrophobicContact CZ-CD1 4.02Å; F395-I455 HydrophobicContact CZ-CG1 3.88Å; L444-I455 HydrophobicContact CD2-CD1 3.63Å; S451-I455 WeakPolarHBondContact O-CG1 3.46Å; S451-I455 PolarHBondContact O-N 3.23Å; L452-I455 PolarHBondContact O-N 3.18Å; I453-I455 VanDerWaalsContact C-N 3.35Å; I453-I455 PolarHBondContact O-N 2.86Å; I455-I457 VanDerWaalsContact C-N 3.33Å; I455-I457 PolarHBondContact O-N 2.85Å; I455-A458 WeakPolarHBondContact O-CB 3.48Å; I455-A458 PolarHBondContact O-N 3.01Å; I455-L459 HydrophobicContact CG2-CD1 3.78Å; I455-L459 HydrophobicContact CG2-CG 4.14Å; I455-L459 WeakPolarHBondContact O-CB 3.44Å; I455-L459 WeakPolarHBondContact O-CG 3.33Å; I455-L459 PolarHBondContact O-N 2.69Å
456	A	91.2	Very high	88.1	Confident	57 Å²	57	54.8 Å²	54.8	47%	0.471	30%	0.303	S	S	.	.	H	α-helix	trans	-61.8	-41.3	179.5	0	0	0	0	0	111.5	L452 I453 L459 S460	L452-A456 VanDerWaalsContact O-CB 3.31Å; L452-A456 WeakPolarHBondContact O-CB 3.48Å; L452-A456 PolarHBondContact O-N 3.28Å; I453-A456 PolarHBondContact O-N 3.2Å; A456-L459 PolarHBondContact O-N 3.37Å; A456-S460 WeakPolarHBondContact O-CB 3.47Å; A456-S460 PolarHBondContact O-N 3.42Å
457	I	88.8	Confident	88	Confident	40 Å²	40	55.6 Å²	55.6	21%	0.205	30%	0.303	C	S	.	.	H	α-helix	trans	-65.4	-41.5	174.9	-64.3	167.6	0	0	0	110.5	W129 L133 V134 I453 G454 I455 L459 S460	W129-I457 PolarHBondContact NE1-O 2.94Å; L133-I457 HydrophobicContact CB-CG2 4.2Å; L133-I457 HydrophobicContact CD1-CG2 4.27Å; V134-I457 HydrophobicContact CG2-CB 4.18Å; V134-I457 HydrophobicContact CG2-CD1 3.92Å; V134-I457 HydrophobicContact CG2-CG2 3.6Å; I453-I457 HydrophobicContact CG2-CD1 3.89Å; I453-I457 HydrophobicContact CG2-CG1 4.47Å; I453-I457 WeakPolarHBondContact O-CG1 3.33Å; I453-I457 PolarHBondContact O-N 3.48Å; G454-I457 PolarHBondContact O-N 2.97Å; I455-I457 VanDerWaalsContact C-N 3.33Å; I455-I457 PolarHBondContact O-N 2.85Å; I457-L459 PolarHBondContact O-N 3.27Å; I457-S460 WeakPolarHBondContact O-CB 3.43Å; I457-S460 PolarHBondContact O-N 3.05Å; I457-S460 PolarHBondContact O-OG 2.83Å
458	A	89.6	Confident	87.8	Confident	19 Å²	19	55.6 Å²	55.6	16%	0.157	31%	0.31	C	S	.	.	H	α-helix	trans	-60.7	-47	174.7	0	0	0	0	0	112.1	I126 V130 G454 I455 S460 G461	I126-A458 HydrophobicContact CG2-CB 4.33Å; V130-A458 HydrophobicContact CG2-CB 3.51Å; G454-A458 PolarHBondContact O-N 3.13Å; I455-A458 WeakPolarHBondContact O-CB 3.48Å; I455-A458 PolarHBondContact O-N 3.01Å; A458-S460 VanDerWaalsContact C-N 3.28Å; A458-S460 PolarHBondContact O-N 2.68Å; A458-G461 PolarHBondContact O-N 3.29Å; A458-G461 VanDerWaalsContact O-N 3.12Å
459	L	92.1	Very high	87.5	Confident	109 Å²	109	54.6 Å²	54.6	57%	0.571	30%	0.303	S	S	*	.	H	α-helix	trans	-67.7	-27.8	178.2	-68.6	177.5	0	0	0	112.7	I455 A456 I457 G461 V462 P463	I455-L459 HydrophobicContact CG2-CD1 3.78Å; I455-L459 HydrophobicContact CG2-CG 4.14Å; I455-L459 WeakPolarHBondContact O-CB 3.44Å; I455-L459 WeakPolarHBondContact O-CG 3.33Å; I455-L459 PolarHBondContact O-N 2.69Å; A456-L459 PolarHBondContact O-N 3.37Å; I457-L459 PolarHBondContact O-N 3.27Å; L459-G461 PolarHBondContact O-N 3.07Å; L459-V462 VanDerWaalsContact O-CB 3.32Å; L459-V462 WeakPolarHBondContact O-CB 3.44Å; L459-V462 WeakPolarHBondContact O-CG2 3.11Å; L459-V462 PolarHBondContact O-N 2.91Å; L459-P463 WeakPolarHBondContact O-CD 3.3Å
460	S	93.9	Very high	87.1	Confident	45 Å²	45	56.1 Å²	56.1	32%	0.315	30%	0.302	S	S	.	.	H	α-helix	trans	-61.3	-23.1	173.1	79.8	0	0	0	0	112.3	W129 A456 I457 A458 V462 P463 F464	W129-S460 PolarHBondContact NE1-OG 3.22Å; W129-S460 VanDerWaalsContact NE1-OG 3.13Å; A456-S460 WeakPolarHBondContact O-CB 3.47Å; A456-S460 PolarHBondContact O-N 3.42Å; I457-S460 WeakPolarHBondContact O-CB 3.43Å; I457-S460 PolarHBondContact O-N 3.05Å; I457-S460 PolarHBondContact O-OG 2.83Å; A458-S460 VanDerWaalsContact C-N 3.28Å; A458-S460 PolarHBondContact O-N 2.68Å; S460-V462 VanDerWaalsContact C-N 3.28Å; S460-V462 PolarHBondContact O-N 3.19Å; S460-P463 WeakPolarHBondContact O-CD 3.46Å; S460-P463 VanDerWaalsContact O-CG 3.23Å; S460-P463 WeakPolarHBondContact O-CG 3.47Å; S460-F464 WeakPolarHBondContact O-CD2 3.25Å
461	G	90.4	Very high	86.7	Confident	0 Å²	0	57.8 Å²	57.8	0%	0	31%	0.311	C	S	.	.	H	α-helix	trans	-68.1	-25.1	173.9	0	0	0	0	0	113.5	F125 A458 L459 F464 Y465	F125-G461 WeakPolarHBondContact CE1-O 3.3Å; A458-G461 PolarHBondContact O-N 3.29Å; A458-G461 VanDerWaalsContact O-N 3.12Å; L459-G461 PolarHBondContact O-N 3.07Å; G461-F464 PolarHBondContact O-N 3.48Å; G461-Y465 PolarHBondContact O-N 3.29Å
462	V	92.1	Very high	85.9	Confident	40 Å²	40	60.7 Å²	60.7	24%	0.242	33%	0.329	C	S	.	.	H	α-helix	trans	-58.4	-53.8	-177.7	-179.6	0	0	0	0	112.7	F122 I126 L459 S460 F464 Y465 F466	F122-V462 HydrophobicContact CE2-CG1 4.27Å; F122-V462 HydrophobicContact CE2-CG2 4.23Å; F122-V462 HydrophobicContact CZ-CG1 4.34Å; F122-V462 HydrophobicContact CZ-CG2 3.95Å; I126-V462 HydrophobicContact CD1-CG2 3.93Å; L459-V462 VanDerWaalsContact O-CB 3.32Å; L459-V462 WeakPolarHBondContact O-CB 3.44Å; L459-V462 WeakPolarHBondContact O-CG2 3.11Å; L459-V462 PolarHBondContact O-N 2.91Å; S460-V462 VanDerWaalsContact C-N 3.28Å; S460-V462 PolarHBondContact O-N 3.19Å; V462-F464 VanDerWaalsContact C-N 3.27Å; V462-F464 PolarHBondContact O-N 3.48Å; V462-Y465 PolarHBondContact O-N 3.14Å; V462-F466 HydrophobicContact CG1-CD2 3.86Å; V462-F466 HydrophobicContact CG1-CE2 3.7Å; V462-F466 VanDerWaalsContact O-CD2 3.27Å; V462-F466 WeakPolarHBondContact O-CD2 3.28Å; V462-F466 PolarHBondContact O-N 3.32Å; V462-F466 VanDerWaalsContact O-N 3.14Å
463	P	90	Very high	84.8	Confident	75 Å²	75	61.8 Å²	61.8	49%	0.487	33%	0.332	S	S	.	.	H	α-helix	trans	-61.6	-34.9	177.2	23.5	-34.9	0	0	0	112.8	L459 S460 F466 M467	L459-P463 WeakPolarHBondContact O-CD 3.3Å; S460-P463 WeakPolarHBondContact O-CD 3.46Å; S460-P463 VanDerWaalsContact O-CG 3.23Å; S460-P463 WeakPolarHBondContact O-CG 3.47Å; P463-F466 PolarHBondContact O-N 3.31Å; P463-M467 VanDerWaalsContact O-CB 3.28Å; P463-M467 WeakPolarHBondContact O-CB 3.42Å; P463-M467 PolarHBondContact O-N 3.23Å
464	F	88.1	Confident	83.7	Confident	112 Å²	112	63.2 Å²	63.2	49%	0.491	35%	0.348	S	S	.	.	H	α-helix	trans	-69	-37.1	177	-79.3	-90.2	0	0	0	112.5	F125 W129 S460 G461 V462 M467 G468	F125-F464 HydrophobicContact CE1-CB 4.49Å; F125-F464 HydrophobicContact CZ-CB 4.11Å; W129-F464 HydrophobicContact CH2-CB 3.99Å; W129-F464 AromaticContact CH2-CD1 3.75Å; W129-F464 HydrophobicContact CH2-CD1 3.75Å; W129-F464 AromaticContact CH2-CD2 3.71Å; W129-F464 HydrophobicContact CH2-CD2 3.71Å; W129-F464 HydrophobicContact CH2-CE1 4.1Å; W129-F464 HydrophobicContact CH2-CE2 4.07Å; W129-F464 AromaticContact CH2-CG 3.53Å; W129-F464 HydrophobicContact CH2-CG 3.53Å; W129-F464 HydrophobicContact CH2-CZ 4.25Å; W129-F464 HydrophobicContact CZ2-CB 4.43Å; W129-F464 AromaticContact CZ2-CD2 3.7Å; W129-F464 HydrophobicContact CZ2-CD2 3.7Å; W129-F464 HydrophobicContact CZ2-CE2 4.02Å; W129-F464 AromaticContact CZ2-CG 3.98Å; W129-F464 HydrophobicContact CZ2-CG 3.98Å; W129-F464 HydrophobicContact CZ3-CB 4.13Å; W129-F464 HydrophobicContact CZ3-CD1 4.3Å; W129-F464 HydrophobicContact CZ3-CG 4.12Å; S460-F464 WeakPolarHBondContact O-CD2 3.25Å; G461-F464 PolarHBondContact O-N 3.48Å; V462-F464 VanDerWaalsContact C-N 3.27Å; V462-F464 PolarHBondContact O-N 3.48Å; F464-M467 PolarHBondContact O-N 3.49Å; F464-G468 WeakPolarHBondContact O-CA 3.41Å; F464-G468 PolarHBondContact O-N 3.4Å
465	Y	88.1	Confident	82.9	Confident	31 Å²	31	69.3 Å²	69.3	12%	0.122	38%	0.376	C	S	.	.	H	α-helix	trans	-62.1	-48.5	174.1	-179.9	-98.9	0	0	0	111.4	F122 F125 G461 V462 M467 V469 Y470	F122-Y465 HydrophobicContact CB-CE1 3.97Å; F122-Y465 HydrophobicContact CB-CE2 4.48Å; F122-Y465 AromaticContact CD2-CD1 3.43Å; F122-Y465 HydrophobicContact CD2-CD1 3.43Å; F122-Y465 VanDerWaalsContact CD2-CD1 3.43Å; F122-Y465 HydrophobicContact CD2-CD2 4.4Å; F122-Y465 AromaticContact CD2-CE1 3.68Å; F122-Y465 HydrophobicContact CD2-CE1 3.68Å; F122-Y465 AromaticContact CD2-CG 3.8Å; F122-Y465 HydrophobicContact CD2-CG 3.8Å; F122-Y465 HydrophobicContact CE2-CD1 4.09Å; F122-Y465 HydrophobicContact CE2-CG 4.37Å; F122-Y465 HydrophobicContact CG-CD1 4.45Å; F122-Y465 HydrophobicContact CG-CE1 4.29Å; F122-Y465 PolarHBondContact N-OH 2.93Å; F125-Y465 HydrophobicContact CB-CD2 3.44Å; F125-Y465 VanDerWaalsContact CB-CD2 3.44Å; F125-Y465 HydrophobicContact CB-CE2 3.83Å; F125-Y465 HydrophobicContact CB-CG 4.47Å; F125-Y465 AromaticContact CD1-CD2 3.82Å; F125-Y465 HydrophobicContact CD1-CD2 3.82Å; F125-Y465 HydrophobicContact CD1-CG 4.18Å; F125-Y465 AromaticContact CD2-CD2 3.92Å; F125-Y465 HydrophobicContact CD2-CD2 3.92Å; F125-Y465 AromaticContact CG-CD2 3.44Å; F125-Y465 HydrophobicContact CG-CD2 3.44Å; F125-Y465 VanDerWaalsContact CG-CD2 3.44Å; F125-Y465 HydrophobicContact CG-CE2 4.29Å; F125-Y465 HydrophobicContact CG-CG 4.26Å; G461-Y465 PolarHBondContact O-N 3.29Å; V462-Y465 PolarHBondContact O-N 3.14Å; Y465-M467 VanDerWaalsContact C-N 3.34Å; Y465-M467 PolarHBondContact O-N 2.94Å; Y465-V469 HydrophobicContact CD2-CB 3.78Å; Y465-V469 HydrophobicContact CD2-CG1 4.23Å; Y465-V469 HydrophobicContact CD2-CG2 3.88Å; Y465-V469 HydrophobicContact CE2-CB 3.73Å; Y465-V469 HydrophobicContact CE2-CG1 3.66Å; Y465-V469 HydrophobicContact CE2-CG2 4.14Å; Y465-V469 HydrophobicContact CG-CB 4.44Å; Y465-V469 WeakPolarHBondContact O-CA 3.29Å; Y465-V469 WeakPolarHBondContact O-CB 3.32Å; Y465-V469 PolarHBondContact O-N 3.37Å; Y465-Y470 PolarHBondContact O-N 3.12Å
466	F	86.2	Confident	82.4	Confident	91 Å²	91	69.4 Å²	69.4	40%	0.399	37%	0.372	S	S	.	.	I	π-helix	trans	-63.6	-42.8	-179.5	-79	-70.1	0	0	0	111.4	F122 V462 P463 Y470 L471	F122-F466 HydrophobicContact CE2-CE2 4.49Å; V462-F466 HydrophobicContact CG1-CD2 3.86Å; V462-F466 HydrophobicContact CG1-CE2 3.7Å; V462-F466 VanDerWaalsContact O-CD2 3.27Å; V462-F466 WeakPolarHBondContact O-CD2 3.28Å; V462-F466 PolarHBondContact O-N 3.32Å; V462-F466 VanDerWaalsContact O-N 3.14Å; P463-F466 PolarHBondContact O-N 3.31Å; F466-Y470 AromaticContact CD1-CD1 3.84Å; F466-Y470 HydrophobicContact CD1-CD1 3.84Å; F466-Y470 AromaticContact CD1-CG 3.92Å; F466-Y470 HydrophobicContact CD1-CG 3.92Å; F466-Y470 HydrophobicContact CE1-CD1 4.31Å; F466-Y470 HydrophobicContact CE1-CG 4.29Å; F466-L471 WeakPolarHBondContact O-CD1 3.29Å; F466-L471 PolarHBondContact O-N 3.2Å
467	M	81.9	Confident	81.8	Confident	80 Å²	80	69.8 Å²	69.8	39%	0.394	37%	0.37	S	S	.	.	I	π-helix	trans	-72.3	-38.9	-179.2	-172.1	-176.9	-62.4	0	0	113.7	P463 F464 Y465 I480	P463-M467 VanDerWaalsContact O-CB 3.28Å; P463-M467 WeakPolarHBondContact O-CB 3.42Å; P463-M467 PolarHBondContact O-N 3.23Å; F464-M467 PolarHBondContact O-N 3.49Å; Y465-M467 VanDerWaalsContact C-N 3.34Å; Y465-M467 PolarHBondContact O-N 2.94Å; M467-I480 HydrophobicContact CE-CD1 4.14Å; M467-I480 HydrophobicContact CG-CD1 4.38Å; M467-I480 HydrophobicContact SD-CD1 3.36Å; M467-I480 WeakPolarHBondContact SD-CD1 3.44Å
468	G	79	Confident	81.3	Confident	28 Å²	28	73.5 Å²	73.5	29%	0.289	39%	0.39	S	S	.	.	I	π-helix	trans	-92.4	-43.3	-172.3	0	0	0	0	0	113.7	F464 R476	F464-G468 WeakPolarHBondContact O-CA 3.41Å; F464-G468 PolarHBondContact O-N 3.4Å; G468-R476 PolarHBondContact O-NE 2.84Å; G468-R476 PolarHBondContact O-NH2 3.26Å
469	V	79.5	Confident	80.9	Confident	42 Å²	42	80.2 Å²	80.2	26%	0.255	42%	0.415	S	S	.	.	I	π-helix	trans	-105.6	-46.5	-170.2	-175.1	0	0	0	0	111.8	F125 Y465	F125-V469 HydrophobicContact CD2-CG2 4.03Å; F125-V469 HydrophobicContact CE2-CG2 4.23Å; Y465-V469 HydrophobicContact CD2-CB 3.78Å; Y465-V469 HydrophobicContact CD2-CG1 4.23Å; Y465-V469 HydrophobicContact CD2-CG2 3.88Å; Y465-V469 HydrophobicContact CE2-CB 3.73Å; Y465-V469 HydrophobicContact CE2-CG1 3.66Å; Y465-V469 HydrophobicContact CE2-CG2 4.14Å; Y465-V469 HydrophobicContact CG-CB 4.44Å; Y465-V469 WeakPolarHBondContact O-CA 3.29Å; Y465-V469 WeakPolarHBondContact O-CB 3.32Å; Y465-V469 PolarHBondContact O-N 3.37Å
470	Y	79.8	Confident	80.4	Confident	160 Å²	160	77.9 Å²	77.9	63%	0.627	40%	0.403	S	S	*	.	I	π-helix	trans	-76.2	-40.7	-174.8	-173.6	-100.2	0	0	0	113.1	Y465 F466	Y465-Y470 PolarHBondContact O-N 3.12Å; F466-Y470 AromaticContact CD1-CD1 3.84Å; F466-Y470 HydrophobicContact CD1-CD1 3.84Å; F466-Y470 AromaticContact CD1-CG 3.92Å; F466-Y470 HydrophobicContact CD1-CG 3.92Å; F466-Y470 HydrophobicContact CE1-CD1 4.31Å; F466-Y470 HydrophobicContact CE1-CG 4.29Å
471	L	75.1	Confident	79.6	Confident	53 Å²	53	81.3 Å²	81.3	28%	0.277	41%	0.409	S	S	.	.	S	Bend	trans	-74.6	126.6	176.4	-94.9	91.1	0	0	0	110.8	F466 Q475	F466-L471 WeakPolarHBondContact O-CD1 3.29Å; F466-L471 PolarHBondContact O-N 3.2Å; L471-Q475 HydrophobicContact CD2-CB 4.03Å
472	P	67.7	Low	79.3	Confident	64 Å²	64	86 Å²	86	42%	0.416	43%	0.434	S	S	.	.			trans	-59.7	148.5	173.4	9.7	-11.1	0	0	0	110.7	S474 Q475 R476	P472-S474 PolarHBondContact O-N 3.41Å; P472-Q475 HydrophobicContact CG-CB 4.41Å; P472-Q475 HydrophobicContact CG-CG 4.07Å; P472-Q475 PolarHBondContact O-N 3.27Å; P472-R476 PolarHBondContact O-N 3.25Å
473	E	65.6	Low	79	Confident	120 Å²	120	86.8 Å²	86.8	56%	0.561	44%	0.439	S	S	*	.	T	Hydrogen-bonded Turn	trans	-53.2	-28.9	-175.9	-60.5	-138.9	128.5	0	0	114	R476	E473-R476 IonicContact OE1-CZ 3.6Å; E473-R476 IonicContact OE1-NH1 2.75Å; E473-R476 PolarHBondContact OE1-NH1 3.46Å; E473-R476 IonicContact OE1-NH2 3.72Å
474	S	63.3	Low	78.7	Confident	99 Å²	99	86.3 Å²	86.3	69%	0.692	43%	0.432	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.6	-24.9	178	58.7	0	0	0	0	114	P472	P472-S474 PolarHBondContact O-N 3.41Å
475	Q	70	Confident	78.6	Confident	132 Å²	132	82.6 Å²	82.6	62%	0.617	42%	0.422	S	S	*	.	T	Hydrogen-bonded Turn	trans	-99.2	-7.1	-179.7	-63.4	-174.4	5.6	0	0	112.9	L471 P472	L471-Q475 HydrophobicContact CD2-CB 4.03Å; P472-Q475 HydrophobicContact CG-CB 4.41Å; P472-Q475 HydrophobicContact CG-CG 4.07Å; P472-Q475 PolarHBondContact O-N 3.27Å
476	R	77.6	Confident	78.5	Confident	60 Å²	60	83.8 Å²	83.8	23%	0.226	44%	0.438	C	S	.	.	S	Bend	trans	-64.2	139.6	174.7	-63.1	-175.7	-171.1	149.5	2.1	110	G468 P472 E473 L478	G468-R476 PolarHBondContact O-NE 2.84Å; G468-R476 PolarHBondContact O-NH2 3.26Å; P472-R476 PolarHBondContact O-N 3.25Å; E473-R476 IonicContact OE1-CZ 3.6Å; E473-R476 IonicContact OE1-NH1 2.75Å; E473-R476 PolarHBondContact OE1-NH1 3.46Å; E473-R476 IonicContact OE1-NH2 3.72Å; R476-L478 PolarHBondContact O-N 3.43Å
477	P	78.4	Confident	78.6	Confident	66 Å²	66	83.4 Å²	83.4	43%	0.429	44%	0.439	S	S	.	.			trans	-54.2	128.7	178.3	-24.9	32.8	0	0	0	111.6	F479 I480 R481	P477-F479 PolarHBondContact O-N 3.26Å; P477-F479 VanDerWaalsContact O-N 3.1Å; P477-I480 HydrophobicContact CB-CD1 4.18Å; P477-I480 HydrophobicContact CB-CG1 4.16Å; P477-I480 HydrophobicContact CG-CD1 3.96Å; P477-I480 HydrophobicContact CG-CG1 4.47Å; P477-I480 PolarHBondContact O-N 3.2Å; P477-R481 PolarHBondContact O-N 3.23Å; P477-R481 VanDerWaalsContact O-N 3.12Å
478	L	78.4	Confident	78.9	Confident	118 Å²	118	80.7 Å²	80.7	62%	0.618	43%	0.428	S	S	*	.	H	α-helix	trans	-52.2	-36.8	-177.5	-79.2	159.5	0	0	0	112.8	R476 R481 N482	R476-L478 PolarHBondContact O-N 3.43Å; L478-R481 PolarHBondContact O-N 2.99Å; L478-N482 WeakPolarHBondContact O-CB 3.32Å; L478-N482 PolarHBondContact O-N 3.5Å; L478-N482 PolarHBondContact O-ND2 3.41Å; L478-N482 PolarHBondContact O-OD1 3.24Å
479	F	82.1	Confident	79.2	Confident	159 Å²	159	86.4 Å²	86.4	70%	0.697	44%	0.441	S	S	*	.	H	α-helix	trans	-59.5	-48.5	175.6	176.6	-102.8	0	0	0	112.3	P477 R481 N482 V483	P477-F479 PolarHBondContact O-N 3.26Å; P477-F479 VanDerWaalsContact O-N 3.1Å; F479-R481 VanDerWaalsContact C-N 3.34Å; F479-R481 PolarHBondContact O-N 2.93Å; F479-N482 PolarHBondContact O-N 3.48Å; F479-V483 HydrophobicContact CD1-CG2 4.36Å; F479-V483 HydrophobicContact CD2-CG2 4.24Å; F479-V483 HydrophobicContact CE1-CG2 3.97Å; F479-V483 HydrophobicContact CE2-CG2 3.84Å; F479-V483 HydrophobicContact CG-CG2 4.49Å; F479-V483 HydrophobicContact CZ-CG2 3.69Å; F479-V483 WeakPolarHBondContact O-CB 3.31Å; F479-V483 VanDerWaalsContact O-CG2 3.3Å; F479-V483 WeakPolarHBondContact O-CG2 3.34Å; F479-V483 PolarHBondContact O-N 3.01Å
480	I	80.6	Confident	79.7	Confident	60 Å²	60	86.2 Å²	86.2	31%	0.308	45%	0.447	S	S	.	.	H	α-helix	trans	-65.3	-42	-179	-61	-178.1	0	0	0	110.1	M467 P477 N482 V483 L484	M467-I480 HydrophobicContact CE-CD1 4.14Å; M467-I480 HydrophobicContact CG-CD1 4.38Å; M467-I480 HydrophobicContact SD-CD1 3.36Å; M467-I480 WeakPolarHBondContact SD-CD1 3.44Å; P477-I480 HydrophobicContact CB-CD1 4.18Å; P477-I480 HydrophobicContact CB-CG1 4.16Å; P477-I480 HydrophobicContact CG-CD1 3.96Å; P477-I480 HydrophobicContact CG-CG1 4.47Å; P477-I480 PolarHBondContact O-N 3.2Å; I480-N482 VanDerWaalsContact C-N 3.34Å; I480-N482 PolarHBondContact O-N 2.93Å; I480-V483 PolarHBondContact O-N 3.49Å; I480-L484 VanDerWaalsContact O-CB 3.29Å; I480-L484 WeakPolarHBondContact O-CB 3.31Å; I480-L484 PolarHBondContact O-N 2.84Å
481	R	78.8	Confident	80	Confident	118 Å²	118	80.7 Å²	80.7	45%	0.445	43%	0.428	S	S	.	.	H	α-helix	trans	-61.6	-43	176.2	-162.9	175.4	80	-179.7	7.5	111.8	P477 L478 F479 A485	P477-R481 PolarHBondContact O-N 3.23Å; P477-R481 VanDerWaalsContact O-N 3.12Å; L478-R481 PolarHBondContact O-N 2.99Å; F479-R481 VanDerWaalsContact C-N 3.34Å; F479-R481 PolarHBondContact O-N 2.93Å; R481-A485 WeakPolarHBondContact O-CB 3.22Å; R481-A485 PolarHBondContact O-N 2.89Å
482	N	83.7	Confident	80.6	Confident	97 Å²	97	81.1 Å²	81.1	52%	0.519	43%	0.429	S	S	.	.	H	α-helix	trans	-67.5	-42.2	179	-71.2	-13.2	0	0	0	112.1	L478 F479 I480 A486	L478-N482 WeakPolarHBondContact O-CB 3.32Å; L478-N482 PolarHBondContact O-N 3.5Å; L478-N482 PolarHBondContact O-ND2 3.41Å; L478-N482 PolarHBondContact O-OD1 3.24Å; F479-N482 PolarHBondContact O-N 3.48Å; I480-N482 VanDerWaalsContact C-N 3.34Å; I480-N482 PolarHBondContact O-N 2.93Å; N482-A486 VanDerWaalsContact O-CB 3.26Å; N482-A486 WeakPolarHBondContact O-CB 3.36Å; N482-A486 PolarHBondContact O-N 3.34Å
483	V	85.9	Confident	81.6	Confident	58 Å²	58	84.9 Å²	84.9	35%	0.352	44%	0.44	S	S	.	.	H	α-helix	trans	-64.3	-49.2	176.5	170.4	0	0	0	0	110.5	F479 I480 A485 A486 I487	F479-V483 HydrophobicContact CD1-CG2 4.36Å; F479-V483 HydrophobicContact CD2-CG2 4.24Å; F479-V483 HydrophobicContact CE1-CG2 3.97Å; F479-V483 HydrophobicContact CE2-CG2 3.84Å; F479-V483 HydrophobicContact CG-CG2 4.49Å; F479-V483 HydrophobicContact CZ-CG2 3.69Å; F479-V483 WeakPolarHBondContact O-CB 3.31Å; F479-V483 VanDerWaalsContact O-CG2 3.3Å; F479-V483 WeakPolarHBondContact O-CG2 3.34Å; F479-V483 PolarHBondContact O-N 3.01Å; I480-V483 PolarHBondContact O-N 3.49Å; V483-A485 PolarHBondContact O-N 2.66Å; V483-A486 PolarHBondContact O-N 3.37Å; V483-A486 VanDerWaalsContact O-N 3.16Å; V483-I487 HydrophobicContact CG1-CD1 3.69Å; V483-I487 HydrophobicContact CG1-CG1 4.36Å; V483-I487 VanDerWaalsContact O-CG1 3.31Å; V483-I487 WeakPolarHBondContact O-CG1 3.36Å; V483-I487 PolarHBondContact O-N 2.92Å
484	L	83.5	Confident	82.8	Confident	64 Å²	64	85.8 Å²	85.8	34%	0.335	45%	0.448	S	S	.	.	H	α-helix	trans	-61.1	-45.2	178.5	-171	64.9	0	0	0	110.7	P353 I480 A486 I487 T488	P353-L484 HydrophobicContact CB-CD1 4.43Å; I480-L484 VanDerWaalsContact O-CB 3.29Å; I480-L484 WeakPolarHBondContact O-CB 3.31Å; I480-L484 PolarHBondContact O-N 2.84Å; L484-A486 VanDerWaalsContact C-N 3.3Å; L484-A486 PolarHBondContact O-N 3.46Å; L484-I487 PolarHBondContact O-N 3.44Å; L484-T488 VanDerWaalsContact O-CB 3.27Å; L484-T488 WeakPolarHBondContact O-CB 3.25Å; L484-T488 PolarHBondContact O-N 3.01Å; L484-T488 PolarHBondContact O-OG1 2.85Å
485	A	84.6	Confident	83.9	Confident	35 Å²	35	81.9 Å²	81.9	29%	0.289	42%	0.42	S	S	.	.	H	α-helix	trans	-64.8	-31.2	176.4	0	0	0	0	0	113.5	R481 V483 R489	R481-A485 WeakPolarHBondContact O-CB 3.22Å; R481-A485 PolarHBondContact O-N 2.89Å; V483-A485 PolarHBondContact O-N 2.66Å; A485-R489 WeakPolarHBondContact O-CB 3.49Å; A485-R489 WeakPolarHBondContact O-CG 3.41Å; A485-R489 PolarHBondContact O-N 2.96Å; A485-R489 VanDerWaalsContact O-N 3.09Å; A485-R489 PolarHBondContact O-NE 2.97Å
486	A	87.9	Confident	84.8	Confident	56 Å²	56	82 Å²	82	46%	0.463	42%	0.419	S	S	.	.	H	α-helix	trans	-72.5	-45	174.9	0	0	0	0	0	111.3	N482 V483 L484 R489 G490	N482-A486 VanDerWaalsContact O-CB 3.26Å; N482-A486 WeakPolarHBondContact O-CB 3.36Å; N482-A486 PolarHBondContact O-N 3.34Å; V483-A486 PolarHBondContact O-N 3.37Å; V483-A486 VanDerWaalsContact O-N 3.16Å; L484-A486 VanDerWaalsContact C-N 3.3Å; L484-A486 PolarHBondContact O-N 3.46Å; A486-R489 PolarHBondContact O-N 2.93Å; A486-G490 PolarHBondContact O-N 2.9Å
487	I	88.1	Confident	85.2	Confident	82 Å²	82	79.3 Å²	79.3	42%	0.421	41%	0.41	S	S	.	.	H	α-helix	trans	-61	-47.6	175	-68.6	169.7	0	0	0	109.9	L355 V483 L484 R489 G490 I491	L355-I487 HydrophobicContact CD2-CG2 3.93Å; V483-I487 HydrophobicContact CG1-CD1 3.69Å; V483-I487 HydrophobicContact CG1-CG1 4.36Å; V483-I487 VanDerWaalsContact O-CG1 3.31Å; V483-I487 WeakPolarHBondContact O-CG1 3.36Å; V483-I487 PolarHBondContact O-N 2.92Å; L484-I487 PolarHBondContact O-N 3.44Å; I487-R489 PolarHBondContact O-N 3.35Å; I487-G490 PolarHBondContact O-N 2.92Å; I487-I491 HydrophobicContact CG2-CD1 3.69Å; I487-I491 WeakPolarHBondContact O-CG1 3.15Å; I487-I491 PolarHBondContact O-N 2.91Å
488	T	86.6	Confident	85.5	Confident	24 Å²	24	79.6 Å²	79.6	15%	0.147	41%	0.41	C	S	.	.	H	α-helix	trans	-59.6	-49.3	179.5	-62.1	0	0	0	0	111.4	L355 M358 L484 G490 I491 Q492	L355-T488 HydrophobicContact CD1-CG2 4.41Å; M358-T488 HydrophobicContact CE-CG2 3.3Å; M358-T488 HydrophobicContact SD-CG2 4.3Å; L484-T488 VanDerWaalsContact O-CB 3.27Å; L484-T488 WeakPolarHBondContact O-CB 3.25Å; L484-T488 PolarHBondContact O-N 3.01Å; L484-T488 PolarHBondContact O-OG1 2.85Å; T488-G490 VanDerWaalsContact C-N 3.34Å; T488-G490 PolarHBondContact O-N 3.1Å; T488-I491 PolarHBondContact O-N 3.27Å; T488-Q492 HydrophobicContact CG2-CG 4.48Å; T488-Q492 WeakPolarHBondContact O-CB 3.33Å; T488-Q492 VanDerWaalsContact O-CG 3.27Å; T488-Q492 WeakPolarHBondContact O-CG 3.44Å; T488-Q492 PolarHBondContact O-N 3.29Å
489	R	86.9	Confident	85.5	Confident	148 Å²	148	76.9 Å²	76.9	56%	0.558	40%	0.396	S	S	*	.	H	α-helix	trans	-61.5	-41.8	175.1	-80.2	-176.9	-80.4	177.9	-7.9	112.4	A485 A486 I487 I491 Q492 H493	A485-R489 WeakPolarHBondContact O-CB 3.49Å; A485-R489 WeakPolarHBondContact O-CG 3.41Å; A485-R489 PolarHBondContact O-N 2.96Å; A485-R489 VanDerWaalsContact O-N 3.09Å; A485-R489 PolarHBondContact O-NE 2.97Å; A486-R489 PolarHBondContact O-N 2.93Å; I487-R489 PolarHBondContact O-N 3.35Å; R489-I491 VanDerWaalsContact C-N 3.35Å; R489-I491 PolarHBondContact O-N 2.93Å; R489-Q492 PolarHBondContact O-N 2.77Å; R489-H493 PolarHBondContact O-CD2 2.86Å; R489-H493 PolarHBondContact O-N 3.37Å
490	G	88.9	Confident	84.8	Confident	38 Å²	38	71.9 Å²	71.9	39%	0.392	38%	0.378	S	S	.	.	H	α-helix	trans	-58.5	-45.8	176.7	0	0	0	0	0	112.2	A486 I487 T488 H493 L494	A486-G490 PolarHBondContact O-N 2.9Å; I487-G490 PolarHBondContact O-N 2.92Å; T488-G490 VanDerWaalsContact C-N 3.34Å; T488-G490 PolarHBondContact O-N 3.1Å; G490-H493 PolarHBondContact O-N 3.01Å; G490-L494 WeakPolarHBondContact O-CB 3.25Å; G490-L494 PolarHBondContact O-N 2.95Å
491	I	87.3	Confident	83.6	Confident	43 Å²	43	77.8 Å²	77.8	22%	0.221	41%	0.405	C	S	.	.	H	α-helix	trans	-71.5	-38.7	179	-70.9	167.6	0	0	0	111.7	L355 P368 I487 T488 R489 H493 L494 C495	L355-I491 HydrophobicContact CD1-CB 3.72Å; L355-I491 HydrophobicContact CD1-CD1 3.74Å; L355-I491 HydrophobicContact CD1-CG1 4.32Å; L355-I491 HydrophobicContact CD1-CG2 3.59Å; L355-I491 HydrophobicContact CD2-CD1 3.61Å; L355-I491 HydrophobicContact CG-CD1 4.15Å; P368-I491 HydrophobicContact CB-CG2 4.15Å; P368-I491 HydrophobicContact CG-CG2 3.7Å; I487-I491 HydrophobicContact CG2-CD1 3.69Å; I487-I491 WeakPolarHBondContact O-CG1 3.15Å; I487-I491 PolarHBondContact O-N 2.91Å; T488-I491 PolarHBondContact O-N 3.27Å; R489-I491 VanDerWaalsContact C-N 3.35Å; R489-I491 PolarHBondContact O-N 2.93Å; I491-H493 VanDerWaalsContact C-N 3.31Å; I491-H493 PolarHBondContact O-N 3.45Å; I491-L494 PolarHBondContact O-N 2.94Å; I491-C495 HydrophobicContact CG2-CB 4.46Å; I491-C495 VanDerWaalsContact O-CB 3.28Å; I491-C495 WeakPolarHBondContact O-CB 3.38Å; I491-C495 PolarHBondContact O-N 3.26Å
492	Q	87.6	Confident	82.1	Confident	63 Å²	63	76 Å²	76	29%	0.294	40%	0.404	S	S	.	.	H	α-helix	trans	-56.6	-46.1	173.6	-76.6	176.5	-33.7	0	0	111.5	M358 T488 R489 F496 C497	M358-Q492 HydrophobicContact CE-CG 3.99Å; M358-Q492 VanDerWaalsContact CE-NE2 3.31Å; M358-Q492 HydrophobicContact SD-CG 3.49Å; M358-Q492 WeakPolarHBondContact SD-CG 3.43Å; T488-Q492 HydrophobicContact CG2-CG 4.48Å; T488-Q492 WeakPolarHBondContact O-CB 3.33Å; T488-Q492 VanDerWaalsContact O-CG 3.27Å; T488-Q492 WeakPolarHBondContact O-CG 3.44Å; T488-Q492 PolarHBondContact O-N 3.29Å; R489-Q492 PolarHBondContact O-N 2.77Å; Q492-F496 WeakPolarHBondContact O-CA 3.39Å; Q492-F496 PolarHBondContact O-N 3.48Å; Q492-C497 PolarHBondContact O-N 2.95Å
493	H	87.7	Confident	80.1	Confident	143 Å²	143	77.2 Å²	77.2	66%	0.662	41%	0.41	S	S	*	.	H	α-helix	trans	-71.2	-41.1	177.5	-71.3	-56	0	0	0	113	R489 G490 I491	R489-H493 PolarHBondContact O-CD2 2.86Å; R489-H493 PolarHBondContact O-N 3.37Å; G490-H493 PolarHBondContact O-N 3.01Å; I491-H493 VanDerWaalsContact C-N 3.31Å; I491-H493 PolarHBondContact O-N 3.45Å
494	L	90.1	Very high	77.7	Confident	138 Å²	138	78.8 Å²	78.8	72%	0.723	42%	0.42	S	S	*	.	H	α-helix	trans	-68.6	-40.7	-178.6	-177.1	66.4	0	0	0	112.3	G490 I491	G490-L494 WeakPolarHBondContact O-CB 3.25Å; G490-L494 PolarHBondContact O-N 2.95Å; I491-L494 PolarHBondContact O-N 2.94Å
495	C	87.3	Confident	75.5	Confident	17 Å²	17	79.7 Å²	79.7	12%	0.115	43%	0.428	C	S	.	.	H	α-helix	trans	-104	-1.4	-172.4	-58.9	0	0	0	0	113.5	H360 I367 I491 C497	H360-C495 PolarHBondContact CD2-O 2.95Å; I367-C495 HydrophobicContact CG2-CB 4.27Å; I491-C495 HydrophobicContact CG2-CB 4.46Å; I491-C495 VanDerWaalsContact O-CB 3.28Å; I491-C495 WeakPolarHBondContact O-CB 3.38Å; I491-C495 PolarHBondContact O-N 3.26Å; C495-C497 WeakPolarHBondContact CB-SG 3.4Å; C495-C497 PolarHBondContact O-N 3.11Å; C495-C497 PolarHBondContact O-SG 3.08Å
496	F	88.6	Confident	73.2	Confident	135 Å²	135	85.7 Å²	85.7	59%	0.592	45%	0.45	S	S	*	.	T	Hydrogen-bonded Turn	trans	49.5	45.9	-174.4	-64.4	-88.6	0	0	0	112.5	I361 Q492	I361-F496 WeakPolarHBondContact CG1-O 3.44Å; I361-F496 PolarHBondContact N-O 3.36Å; I361-F496 VanDerWaalsContact N-O 3.15Å; Q492-F496 WeakPolarHBondContact O-CA 3.39Å; Q492-F496 PolarHBondContact O-N 3.48Å
497	C	86.3	Confident	70.5	Confident	4 Å²	4	90.7 Å²	90.7	3%	0.027	46%	0.464	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-104.6	147.1	-178.9	-59.8	0	0	0	0	111.9	M358 I359 Q492 C495	M358-C497 HydrophobicContact CB-CB 3.73Å; I359-C497 CarbonylContact O-C 3.47Å; I359-C497 VanDerWaalsContact O-CA 3.24Å; I359-C497 WeakPolarHBondContact O-CA 3.48Å; Q492-C497 PolarHBondContact O-N 2.95Å; C495-C497 WeakPolarHBondContact CB-SG 3.4Å; C495-C497 PolarHBondContact O-N 3.11Å; C495-C497 PolarHBondContact O-SG 3.08Å
498	V	84.6	Confident	67.7	Low	71 Å²	71	93.4 Å²	93.4	43%	0.43	47%	0.472	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-125.9	151.8	175.9	-68.4	0	0	0	0	109.5	M358 I359 I361	M358-V498 CarbonylContact C-O 3.54Å; M358-V498 WeakPolarHBondContact CA-O 3.18Å; I359-V498 PolarHBondContact N-O 2.99Å; I359-V498 PolarHBondContact O-N 3.46Å; I361-V498 HydrophobicContact CD1-CG1 3.96Å; I361-V498 HydrophobicContact CG1-CG1 3.81Å; I361-V498 HydrophobicContact CG1-CG2 3.95Å
499	L	79.1	Confident	65.1	Low	61 Å²	61	99.4 Å²	99.4	32%	0.319	50%	0.497	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-67.4	136.1	170.2	-158.2	72	0	0	0	108.3	D354 S357 M358	D354-L499 HydrophobicContact CB-CD1 3.62Å; D354-L499 HydrophobicContact CB-CD2 4.38Å; D354-L499 WeakPolarHBondContact O-CD1 3.37Å; S357-L499 WeakPolarHBondContact OG-CD1 3.43Å; M358-L499 HydrophobicContact CE-CD1 4.41Å; M358-L499 HydrophobicContact CG-CD1 4.14Å
500	T	66.1	Low	62.6	Low	54 Å²	54	98 Å²	98	33%	0.331	50%	0.5	S	S	.	.			trans	-62	138	164.6	38	0	0	0	0	109	I359 L502	I359-T500 HydrophobicContact CB-CG2 4.44Å; I359-T500 HydrophobicContact CD1-CG2 3.22Å; I359-T500 HydrophobicContact CG1-CG2 3.68Å; T500-L502 PolarHBondContact O-N 3.27Å
501	E	55.3	Low	60	Low	184 Å²	184	102.7 Å²	102.7	86%	0.86	51%	0.512	S	S	*	.			trans	-54.4	109.4	164.7	-71.8	-175.4	170.6	0	0	107.1	D503	E501-D503 PolarHBondContact O-N 3.5Å
502	L	48.5	Very low	57.4	Low	81 Å²	81	108.3 Å²	108.3	42%	0.424	54%	0.539	S	S	.	.			trans	-56.8	135.8	164.8	-74.1	159.9	0	0	0	105.8	R348 T500 V504	R348-L502 HydrophobicContact CB-CD2 4.43Å; R348-L502 HydrophobicContact CG-CD2 4.1Å; T500-L502 PolarHBondContact O-N 3.27Å; L502-V504 VanDerWaalsContact C-N 3.32Å; L502-V504 WeakPolarHBondContact O-CG2 3.32Å; L502-V504 PolarHBondContact O-N 3.32Å
503	D	40.3	Very low	54.9	Low	122 Å²	122	113.6 Å²	113.6	65%	0.652	56%	0.561	S	S	*	*			trans	-50.5	96	176.3	-78.6	-49.2	0	0	0	109.6	E501 T505	E501-D503 PolarHBondContact O-N 3.5Å; D503-T505 PolarHBondContact O-N 2.93Å
504	V	36.7	Very low	52.5	Low	92 Å²	92	112.3 Å²	112.3	56%	0.558	56%	0.563	S	S	*	*	T	Hydrogen-bonded Turn	trans	-65.8	10.3	-176.1	-169.9	0	0	0	0	112	L502	L502-V504 VanDerWaalsContact C-N 3.32Å; L502-V504 WeakPolarHBondContact O-CG2 3.32Å; L502-V504 PolarHBondContact O-N 3.32Å
505	T	36.9	Very low	49.8	Very low	82 Å²	82	116.2 Å²	116.2	50%	0.503	59%	0.585	S	S	.	*	T	Hydrogen-bonded Turn	trans	-92.4	-15.4	-173.2	9.7	0	0	0	0	114.6	D503	D503-T505 PolarHBondContact O-N 2.93Å
506	E	35.5	Very low	47.9	Very low	161 Å²	161	121.2 Å²	121.2	75%	0.752	61%	0.608	S	S	*	*	T	Hydrogen-bonded Turn	trans	-85.9	-40.9	176.3	-71.7	-151.4	149.4	0	0	113.3	K508 K509	E506-K508 VanDerWaalsContact C-N 3.3Å; E506-K508 PolarHBondContact O-N 3.14Å; E506-K509 PolarHBondContact O-N 3.19Å; E506-K509 VanDerWaalsContact O-N 3.08Å
507	E	31.7	Very low	45.8	Very low	161 Å²	161	120.4 Å²	120.4	75%	0.752	61%	0.609	S	S	*	*	H	α-helix	trans	-62.5	-35.5	178.2	-76.3	-175.5	152.3	0	0	112.7	K509 D510 E511	E507-K509 VanDerWaalsContact C-N 3.29Å; E507-K509 PolarHBondContact O-N 3.46Å; E507-D510 PolarHBondContact O-N 2.98Å; E507-E511 PolarHBondContact O-N 2.89Å
508	K	29.8	Very low	43.5	Very low	140 Å²	140	126.9 Å²	126.9	61%	0.609	64%	0.641	S	S	*	*	H	α-helix	trans	-71.7	-18	176.9	-79.5	-173.6	175.9	-179.5	0	114.4	E506 M512	E506-K508 VanDerWaalsContact C-N 3.3Å; E506-K508 PolarHBondContact O-N 3.14Å; K508-M512 WeakPolarHBondContact O-CB 3.32Å; K508-M512 PolarHBondContact O-N 3.33Å; K508-M512 VanDerWaalsContact O-N 3.16Å
509	K	32.4	Very low	41.1	Very low	150 Å²	150	130.2 Å²	130.2	65%	0.652	65%	0.654	S	S	*	*	H	α-helix	trans	-80.7	-26	178.6	-94.2	-177.9	178	173.7	0	113	E506 E507	E506-K509 PolarHBondContact O-N 3.19Å; E506-K509 VanDerWaalsContact O-N 3.08Å; E507-K509 VanDerWaalsContact C-N 3.29Å; E507-K509 PolarHBondContact O-N 3.46Å
510	D	34.1	Very low	38.7	Very low	118 Å²	118	134.5 Å²	134.5	63%	0.631	68%	0.675	S	S	*	*	H	α-helix	trans	-83	-31.8	175.1	-79	-19.1	0	0	0	111.9	E507 K513 T514	E507-D510 PolarHBondContact O-N 2.98Å; D510-K513 PolarHBondContact O-N 3.45Å; D510-T514 PolarHBondContact O-OG1 2.89Å; D510-T514 VanDerWaalsContact O-OG1 3.07Å
511	E	33.6	Very low	36.9	Very low	137 Å²	137	139.9 Å²	139.9	64%	0.64	70%	0.698	S	S	*	*	H	α-helix	trans	-68.5	-39.3	169.2	-71.1	-174.3	158.1	0	0	112	E507 K513 T514	E507-E511 PolarHBondContact O-N 2.89Å; E511-K513 PolarHBondContact O-N 3.31Å; E511-T514 PolarHBondContact O-N 3.28Å; E511-T514 VanDerWaalsContact O-N 3.14Å; E511-T514 PolarHBondContact O-OG1 3.19Å
512	M	33.8	Very low	35.6	Very low	161 Å²	161	136.7 Å²	136.7	79%	0.793	69%	0.686	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.5	-8.8	177	-103.4	-177.7	67.8	0	0	115.3	K508	K508-M512 WeakPolarHBondContact O-CB 3.32Å; K508-M512 PolarHBondContact O-N 3.33Å; K508-M512 VanDerWaalsContact O-N 3.16Å
513	K	35.5	Very low	34.6	Very low	174 Å²	174	141 Å²	141	76%	0.757	71%	0.706	S	S	*	*	T	Hydrogen-bonded Turn	trans	-93.9	-3.5	172.8	-81.1	-178.9	-179.4	172.7	0	113	D510 E511	D510-K513 PolarHBondContact O-N 3.45Å; E511-K513 PolarHBondContact O-N 3.31Å
514	T	35.9	Very low	34.1	Very low	115 Å²	115	142.6 Å²	142.6	71%	0.706	71%	0.711	S	S	*	*			trans	-112.8	4.7	-179.2	30.9	0	0	0	0	114.8	D510 E511	D510-T514 PolarHBondContact O-OG1 2.89Å; D510-T514 VanDerWaalsContact O-OG1 3.07Å; E511-T514 PolarHBondContact O-N 3.28Å; E511-T514 VanDerWaalsContact O-N 3.14Å; E511-T514 PolarHBondContact O-OG1 3.19Å
515	D	33.8	Very low	33.9	Very low	220 Å²	220	147.2 Å²	147.2	100%	1.176	73%	0.725	S	S	*	*			trans	-111.1	0	170.1	-80.9	-20.7	0	0	0	113.4

Retrieved 515 of 515 residues in 3547.6 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).