A0A096NGZ5_PAPAN Loading...

Syntaxin-5

Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Required for Golgi to endoplasmic reticulum retrogade transport, and for intra-Golgi transport.

AlphaFold DB (G7NCS0), UniProt , Accession A0A096NGZ5, Species PAPAN (Papio anubis, Olive baboon), Gene STX5, Length 355 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	32.8	Very low	36.4	Very low	231 Å²	231	172.5 Å²	172.5	100%	1.138	84%	0.839	S	S	*	*				0	116.3	0	-85.4	162	150	0	0	108.7
2	I	33.1	Very low	36.2	Very low	158 Å²	158	168.7 Å²	168.7	81%	0.81	83%	0.833	S	S	*	*			trans	62.1	142	141.8	-53.6	175.5	0	0	0	118.1
3	P	44.3	Very low	36.1	Very low	111 Å²	111	165.8 Å²	165.8	72%	0.721	82%	0.823	S	S	*	*			cis	-141.1	170.4	-19.4	37	-17.8	0	0	0	117.4
4	R	42.6	Very low	36	Very low	226 Å²	226	166.6 Å²	166.6	85%	0.853	82%	0.824	S	S	*	*			trans	-2.7	148.9	147.4	-70.3	176.4	168.7	164.2	-2.9	120.5
5	K	33.3	Very low	35.8	Very low	186 Å²	186	160.5 Å²	160.5	81%	0.809	82%	0.82	S	S	*	*				-153	114.7	118.2	-116.4	170	-176	175.4	0	113.3
6	R	42	Very low	35.7	Very low	234 Å²	234	158.7 Å²	158.7	88%	0.883	82%	0.818	S	S	*	*			trans	-73	142.7	157.4	-76.5	-176	174.9	-165	-2	107.9
7	Y	34.9	Very low	35.7	Very low	214 Å²	214	162.8 Å²	162.8	84%	0.839	82%	0.823	S	S	*	*			trans	-130.2	133.2	156.9	-110.6	-89.7	0	0	0	109
8	G	32.8	Very low	36.1	Very low	63 Å²	63	163.3 Å²	163.3	65%	0.649	83%	0.827	S	S	*	*			trans	-125.1	156.7	170.3	0	0	0	0	0	110.5
9	S	36.7	Very low	35.9	Very low	115 Å²	115	157.8 Å²	157.8	80%	0.804	82%	0.815	S	S	*	*			trans	67.5	124.6	165.1	-71.4	0	0	0	0	120
10	K	32.8	Very low	35.8	Very low	207 Å²	207	158.9 Å²	158.9	90%	0.9	82%	0.821	S	S	*	*				-179.4	140.2	100.2	-92.2	166.5	-178.1	-177	0	112.6
11	N	34.6	Very low	35.7	Very low	153 Å²	153	156.6 Å²	156.6	82%	0.818	82%	0.82	S	S	*	*			trans	-58.6	143.7	161.8	-83.8	-33.4	0	0	0	111.4
12	T	34.8	Very low	35.8	Very low	126 Å²	126	154.8 Å²	154.8	77%	0.773	81%	0.805	S	S	*	*				176.9	141.1	112.1	27.5	0	0	0	0	112.9
13	D	34.7	Very low	35.8	Very low	131 Å²	131	153.4 Å²	153.4	70%	0.701	80%	0.804	S	S	*	*			trans	84.4	112.6	149.5	-69.3	-44.9	0	0	0	124.2
14	Q	34.6	Very low	35.3	Very low	178 Å²	178	156.6 Å²	156.6	83%	0.832	81%	0.81	S	S	*	*			trans	60.2	104.3	130.7	-65	-178.4	14.8	0	0	120.1
15	G	33.7	Very low	34.8	Very low	74 Å²	74	151.6 Å²	151.6	76%	0.763	80%	0.804	S	S	*	*			trans	-147.5	99	153.5	0	0	0	0	0	109.4	Y17	G15-Y17 PolarHBondContact O-N 3.33Å
16	V	32.9	Very low	34.6	Very low	132 Å²	132	151.1 Å²	151.1	80%	0.8	81%	0.809	S	S	*	*			trans	-65.6	116.7	177.6	173.3	0	0	0	0	109.4	L18	V16-L18 HydrophobicContact CG1-CD1 4.35Å
17	Y	36.3	Very low	34.2	Very low	229 Å²	229	144.6 Å²	144.6	90%	0.898	80%	0.8	S	S	*	*			trans	-96.6	109.9	171.3	-129.8	-92.8	0	0	0	109.1	G15	G15-Y17 PolarHBondContact O-N 3.33Å
18	L	42.4	Very low	34.5	Very low	172 Å²	172	140.5 Å²	140.5	90%	0.901	80%	0.799	S	S	*	*			trans	-93.5	101.4	170.8	-109.2	138.7	0	0	0	108.3	V16	V16-L18 HydrophobicContact CG1-CD1 4.35Å
19	G	33.7	Very low	34.8	Very low	58 Å²	58	142 Å²	142	60%	0.598	81%	0.805	S	S	*	*			trans	-136.8	123.1	171.8	0	0	0	0	0	110	S21	G19-S21 PolarHBondContact O-N 3.2Å
20	L	33.3	Very low	34.8	Very low	179 Å²	179	142.8 Å²	142.8	94%	0.937	81%	0.808	S	S	*	*			trans	-68.5	115.5	-174.6	-80.7	122.8	0	0	0	112.7
21	S	32.5	Very low	35.1	Very low	112 Å²	112	138.2 Å²	138.2	78%	0.783	81%	0.809	S	S	*	*			trans	-89	110.7	163.8	-20.4	0	0	0	0	109.2	G19	G19-S21 PolarHBondContact O-N 3.2Å
22	K	35.8	Very low	34.9	Very low	193 Å²	193	134.7 Å²	134.7	84%	0.839	81%	0.808	S	S	*	*			trans	-118.2	81.8	167.5	-147.6	176.9	-173.2	177.8	0	109.4
23	T	33.1	Very low	34.8	Very low	129 Å²	129	134 Å²	134	79%	0.791	81%	0.809	S	S	*	*			trans	-96.1	106.8	166.5	-30.5	0	0	0	0	106.7
24	Q	32.9	Very low	34.7	Very low	178 Å²	178	132.8 Å²	132.8	83%	0.832	81%	0.811	S	S	*	*			trans	-87.9	115.9	178.7	-166	167.5	-3.8	0	0	109.6
25	V	32.2	Very low	34.6	Very low	121 Å²	121	129.2 Å²	129.2	73%	0.733	81%	0.805	S	S	*	*			trans	-75.3	131.8	175.2	177.4	0	0	0	0	109.1
26	L	30.9	Very low	34.8	Very low	175 Å²	175	130.6 Å²	130.6	92%	0.916	80%	0.803	S	S	*	*			trans	-100.8	121.2	171	-170	73.1	0	0	0	108.9
27	S	33.6	Very low	34.7	Very low	98 Å²	98	132.3 Å²	132.3	69%	0.685	81%	0.808	S	S	*	*			trans	-129.9	157	171.9	-75.3	0	0	0	0	110.2
28	P	40.4	Very low	35	Very low	128 Å²	128	129.5 Å²	129.5	83%	0.831	81%	0.806	S	S	*	*			trans	-95.1	173.3	-148.5	37	-34.6	0	0	0	115.9
29	A	38	Very low	35	Very low	93 Å²	93	125.6 Å²	125.6	77%	0.769	80%	0.799	S	S	*	*			trans	-52.1	170.6	-172.6	0	0	0	0	0	118
30	P	37.3	Very low	35.3	Very low	133 Å²	133	128.8 Å²	128.8	86%	0.864	81%	0.809	S	S	*	*				-135	158.3	126.4	35.2	-21.4	0	0	0	114.8
31	A	39.9	Very low	35.7	Very low	111 Å²	111	128.3 Å²	128.3	92%	0.917	81%	0.807	S	S	*	*			trans	-77.6	156	-175.4	0	0	0	0	0	114.5
32	G	29.8	Very low	36.3	Very low	79 Å²	79	128 Å²	128	81%	0.814	80%	0.802	S	S	*	*			trans	-164.1	135.2	168	0	0	0	0	0	110.9
33	S	32.4	Very low	37.4	Very low	112 Å²	112	124 Å²	124	78%	0.783	80%	0.796	S	S	*	*			trans	-94.3	166.4	-157.5	48.4	0	0	0	0	116.6
34	S	32.3	Very low	38.1	Very low	105 Å²	105	124.1 Å²	124.1	73%	0.734	80%	0.799	S	S	*	*			trans	105.4	115.5	141.8	73.6	0	0	0	0	120.9
35	S	33.2	Very low	38.7	Very low	102 Å²	102	122.2 Å²	122.2	71%	0.713	80%	0.799	S	S	*	*			trans	65.6	113.6	133.5	50.6	0	0	0	0	123.4
36	S	37.5	Very low	39.2	Very low	104 Å²	104	120.4 Å²	120.4	73%	0.727	80%	0.797	S	S	*	*			trans	52.1	114.2	132.5	56.7	0	0	0	0	121.2
37	D	31.6	Very low	40	Very low	168 Å²	168	120 Å²	120	90%	0.898	80%	0.795	S	S	*	*				-166	150.8	122	-109.2	-29.9	0	0	0	113.8
38	I	42.6	Very low	40.8	Very low	169 Å²	169	121.1 Å²	121.1	87%	0.867	80%	0.797	S	S	*	*			trans	-89.4	131.5	-170.3	-68.1	163.2	0	0	0	111.3
39	A	41.1	Very low	41.6	Very low	91 Å²	91	120 Å²	120	75%	0.752	79%	0.79	S	S	*	*			trans	-160.7	153.1	154.2	0	0	0	0	0	111.9
40	P	40.8	Very low	42.4	Very low	124 Å²	124	120.8 Å²	120.8	81%	0.805	79%	0.787	S	S	*	*			trans	-86.4	155.9	-158.3	9.5	8	0	0	0	114.7
41	L	42.3	Very low	43.2	Very low	169 Å²	169	119.4 Å²	119.4	89%	0.885	78%	0.779	S	S	*	*			trans	-42.3	130	174.1	-80.4	140.5	0	0	0	114.5
42	P	45.1	Very low	44	Very low	107 Å²	107	119.3 Å²	119.3	70%	0.695	77%	0.769	S	S	*	*	P	Polyproline II helix	trans	-81.3	152.1	154.6	31.7	-28.9	0	0	0	111.1
43	P	57.8	Low	45	Very low	109 Å²	109	122.8 Å²	122.8	71%	0.708	77%	0.768	S	S	*	*	P	Polyproline II helix	trans	-65.8	161.7	-174.6	28.5	-35	0	0	0	112.4	V45	P43-V45 PolarHBondContact O-N 2.93Å
44	P	47.4	Very low	45.8	Very low	130 Å²	130	123.5 Å²	123.5	84%	0.844	77%	0.768	S	S	*	*	P	Polyproline II helix	trans	-61.6	117.4	179.1	25.7	-31.8	0	0	0	109.1	A46	P44-A46 PolarHBondContact O-N 2.85Å
45	V	45.8	Very low	46.6	Very low	138 Å²	138	125.8 Å²	125.8	84%	0.836	77%	0.769	S	S	*	*			trans	-54.1	111.3	170.6	177.1	0	0	0	0	107	P43 L47	P43-V45 PolarHBondContact O-N 2.93Å; V45-L47 PolarHBondContact O-N 2.92Å; V45-L47 VanDerWaalsContact O-N 3.09Å
46	A	43.2	Very low	47.5	Very low	84 Å²	84	124.5 Å²	124.5	69%	0.694	76%	0.76	S	S	*	*			trans	-53.4	118.4	170.9	0	0	0	0	0	107.8	P44 V48	P44-A46 PolarHBondContact O-N 2.85Å; A46-V48 PolarHBondContact O-N 2.79Å
47	L	47	Very low	48.3	Very low	165 Å²	165	125.7 Å²	125.7	86%	0.864	77%	0.767	S	S	*	*			trans	-59	99.4	178	-154.1	83.9	0	0	0	107.8	V45 P49	V45-L47 PolarHBondContact O-N 2.92Å; V45-L47 VanDerWaalsContact O-N 3.09Å; L47-P49 WeakPolarHBondContact O-CD 3.41Å
48	V	52.4	Low	49.9	Very low	122 Å²	122	129.1 Å²	129.1	74%	0.739	77%	0.767	S	S	*	*	P	Polyproline II helix	trans	-57	122.1	168.4	172.7	0	0	0	0	106.4	A46	A46-V48 PolarHBondContact O-N 2.79Å
49	P	57.1	Low	51.1	Low	106 Å²	106	125.9 Å²	125.9	69%	0.688	75%	0.752	S	S	*	*	P	Polyproline II helix	trans	-62.4	129.1	175.7	24	-30.1	0	0	0	108.2	L47	L47-P49 WeakPolarHBondContact O-CD 3.41Å
50	P	53.9	Low	52.9	Low	109 Å²	109	129.6 Å²	129.6	71%	0.708	75%	0.746	S	S	*	*	P	Polyproline II helix	trans	-62.2	145.3	177.6	25.4	-32.1	0	0	0	109.7
51	P	54.1	Low	55	Low	104 Å²	104	127.4 Å²	127.4	68%	0.675	73%	0.731	S	S	*	*	P	Polyproline II helix	trans	-58	147.9	-178.1	22.7	-32.2	0	0	0	111.5
52	P	56.4	Low	56.9	Low	109 Å²	109	126 Å²	126	71%	0.708	72%	0.72	S	S	*	*	S	Bend	trans	-64.8	150.2	169.7	33.2	-32.5	0	0	0	107.4
53	D	52	Low	58.8	Low	151 Å²	151	125.2 Å²	125.2	81%	0.807	71%	0.707	S	S	*	*			trans	94.8	30.8	174.4	-43	-25.8	0	0	0	116.7	M55	D53-M55 VanDerWaalsContact C-N 3.32Å; D53-M55 PolarHBondContact O-N 2.94Å
54	T	48.1	Very low	60.1	Low	128 Å²	128	126.5 Å²	126.5	79%	0.785	70%	0.701	S	S	*	*			trans	-87.7	85.7	138.3	55	0	0	0	0	107.7	S56	T54-S56 PolarHBondContact O-N 3.03Å
55	M	50	Low	61.8	Low	153 Å²	153	124 Å²	124	75%	0.754	68%	0.68	S	S	*	*			trans	-58.2	92.6	162.7	-77.7	-72.8	-128.8	0	0	107.2	D53 C57	D53-M55 VanDerWaalsContact C-N 3.32Å; D53-M55 PolarHBondContact O-N 2.94Å; M55-C57 PolarHBondContact O-N 3.19Å; M55-C57 PolarHBondContact O-SG 2.72Å
56	S	51.1	Low	63.7	Low	75 Å²	75	120.7 Å²	120.7	52%	0.524	66%	0.664	S	S	.	*			trans	-62	94.8	165.7	178.9	0	0	0	0	105.9	T54 R58 D59	T54-S56 PolarHBondContact O-N 3.03Å; S56-R58 PolarHBondContact O-N 2.94Å; S56-D59 PolarHBondContact O-N 3.46Å
57	C	54.5	Low	65.7	Low	129 Å²	129	119.5 Å²	119.5	87%	0.872	65%	0.654	S	S	*	*	T	Hydrogen-bonded Turn	trans	-58.1	1.5	173.8	-6.3	0	0	0	0	112.7	M55	M55-C57 PolarHBondContact O-N 3.19Å; M55-C57 PolarHBondContact O-SG 2.72Å
58	R	65.2	Low	67.2	Low	240 Å²	240	114.1 Å²	114.1	91%	0.906	63%	0.63	S	S	*	*	T	Hydrogen-bonded Turn	trans	-99.5	-24.8	-176.4	-94.5	-179.7	152.6	102.5	-0.9	114.6	S56	S56-R58 PolarHBondContact O-N 2.94Å
59	D	67.3	Low	68.7	Low	100 Å²	100	115.3 Å²	115.3	54%	0.535	63%	0.625	S	S	.	*			trans	-127.6	90.6	-176.6	-167.2	-7.8	0	0	0	111.7	S56 T61	S56-D59 PolarHBondContact O-N 3.46Å; D59-T61 WeakPolarHBondContact OD1-CB 3.33Å; D59-T61 PolarHBondContact OD1-N 3.44Å; D59-T61 PolarHBondContact OD1-OG1 3.09Å; D59-T61 VanDerWaalsContact OD1-OG1 3.09Å
60	R	80.5	Confident	69.9	Low	169 Å²	169	113.6 Å²	113.6	64%	0.638	62%	0.616	S	S	*	*			trans	-98.6	14.8	173.5	-62.1	-176.7	66.6	-163	-0.9	112	Q62 E63 F64	R60-Q62 PolarHBondContact O-N 3.48Å; R60-E63 IonicContact CZ-OE2 3.76Å; R60-E63 IonicContact NE-OE2 2.83Å; R60-E63 PolarHBondContact NE-OE2 2.88Å; R60-E63 IonicContact NH2-OE2 3.84Å; R60-E63 PolarHBondContact NH2-OE2 2.98Å; R60-E63 PolarHBondContact O-N 3.49Å; R60-F64 PolarHBondContact O-N 3.42Å; R60-F64 VanDerWaalsContact O-N 3.07Å
61	T	83.8	Confident	70.9	Confident	79 Å²	79	113.7 Å²	113.7	49%	0.485	61%	0.61	S	S	.	*	H	α-helix	trans	-62.3	-33.1	-178.1	-62.2	0	0	0	0	111	D59 F64 L65	D59-T61 WeakPolarHBondContact OD1-CB 3.33Å; D59-T61 PolarHBondContact OD1-N 3.44Å; D59-T61 PolarHBondContact OD1-OG1 3.09Å; D59-T61 VanDerWaalsContact OD1-OG1 3.09Å; T61-F64 PolarHBondContact O-N 3.1Å; T61-L65 HydrophobicContact CG2-CD1 4.01Å; T61-L65 HydrophobicContact CG2-CG 4.32Å; T61-L65 WeakPolarHBondContact O-CB 3.01Å; T61-L65 WeakPolarHBondContact O-CG 3.46Å; T61-L65 PolarHBondContact O-N 3.27Å
62	Q	82.3	Confident	71.8	Confident	138 Å²	138	115.2 Å²	115.2	65%	0.645	61%	0.607	S	S	*	*	H	α-helix	trans	-70.2	-39	177.7	-63.5	-62.9	-13.4	0	0	113.4	R60 F64 L65 S66	R60-Q62 PolarHBondContact O-N 3.48Å; Q62-F64 VanDerWaalsContact C-N 3.34Å; Q62-L65 PolarHBondContact O-N 3.17Å; Q62-S66 WeakPolarHBondContact O-CB 3.43Å; Q62-S66 PolarHBondContact O-N 3.38Å; Q62-S66 PolarHBondContact O-OG 3.4Å
63	E	84.8	Confident	72.4	Confident	91 Å²	91	115 Å²	115	43%	0.425	60%	0.604	S	S	.	*	H	α-helix	trans	-63.1	-42.1	172.7	-72.6	178.1	-158.6	0	0	111.1	R60 S66 A67	R60-E63 IonicContact CZ-OE2 3.76Å; R60-E63 IonicContact NE-OE2 2.83Å; R60-E63 PolarHBondContact NE-OE2 2.88Å; R60-E63 IonicContact NH2-OE2 3.84Å; R60-E63 PolarHBondContact NH2-OE2 2.98Å; R60-E63 PolarHBondContact O-N 3.49Å; E63-S66 WeakPolarHBondContact CA-OG 3.47Å; E63-S66 PolarHBondContact O-N 3.47Å; E63-S66 PolarHBondContact O-OG 3.49Å; E63-A67 WeakPolarHBondContact O-CB 3.39Å; E63-A67 PolarHBondContact O-N 2.93Å
64	F	84.4	Confident	73.1	Confident	136 Å²	136	117.8 Å²	117.8	60%	0.596	60%	0.604	S	S	*	*	H	α-helix	trans	-63.7	-46.5	176.2	177.1	-100.2	0	0	0	111.9	R60 T61 Q62 S66 A67 C68	R60-F64 PolarHBondContact O-N 3.42Å; R60-F64 VanDerWaalsContact O-N 3.07Å; T61-F64 PolarHBondContact O-N 3.1Å; Q62-F64 VanDerWaalsContact C-N 3.34Å; F64-S66 VanDerWaalsContact C-N 3.34Å; F64-S66 PolarHBondContact O-N 3.41Å; F64-A67 PolarHBondContact O-N 3.22Å; F64-C68 VanDerWaalsContact CZ-SG 3.54Å; F64-C68 PolarHBondContact O-N 3.48Å; F64-C68 PolarHBondContact O-SG 3.39Å; F64-C68 VanDerWaalsContact O-SG 3.38Å
65	L	84.9	Confident	73.9	Confident	77 Å²	77	117 Å²	117	40%	0.403	59%	0.591	S	S	.	*	H	α-helix	trans	-62.8	-39.4	179.2	-73.5	171.2	0	0	0	112.4	T61 Q62 C68 K69	T61-L65 HydrophobicContact CG2-CD1 4.01Å; T61-L65 HydrophobicContact CG2-CG 4.32Å; T61-L65 WeakPolarHBondContact O-CB 3.01Å; T61-L65 WeakPolarHBondContact O-CG 3.46Å; T61-L65 PolarHBondContact O-N 3.27Å; Q62-L65 PolarHBondContact O-N 3.17Å; L65-C68 PolarHBondContact O-N 3.04Å; L65-K69 WeakPolarHBondContact O-CG 3.36Å; L65-K69 PolarHBondContact O-N 3.21Å
66	S	85.4	Confident	74.1	Confident	69 Å²	69	116.8 Å²	116.8	48%	0.483	59%	0.593	S	S	.	*	H	α-helix	trans	-69.8	-38.7	176.7	45.7	0	0	0	0	112	Q62 E63 F64 K69 S70	Q62-S66 WeakPolarHBondContact O-CB 3.43Å; Q62-S66 PolarHBondContact O-N 3.38Å; Q62-S66 PolarHBondContact O-OG 3.4Å; E63-S66 WeakPolarHBondContact CA-OG 3.47Å; E63-S66 PolarHBondContact O-N 3.47Å; E63-S66 PolarHBondContact O-OG 3.49Å; F64-S66 VanDerWaalsContact C-N 3.34Å; F64-S66 PolarHBondContact O-N 3.41Å; S66-K69 PolarHBondContact O-N 3.43Å; S66-S70 WeakPolarHBondContact O-CB 3.46Å; S66-S70 PolarHBondContact O-N 2.98Å
67	A	84.2	Confident	74.4	Confident	60 Å²	60	116.7 Å²	116.7	50%	0.496	60%	0.603	S	S	.	*	H	α-helix	trans	-63.2	-43.2	171.7	0	0	0	0	0	112.6	E63 F64 S70 L71	E63-A67 WeakPolarHBondContact O-CB 3.39Å; E63-A67 PolarHBondContact O-N 2.93Å; F64-A67 PolarHBondContact O-N 3.22Å; A67-S70 PolarHBondContact O-N 3.16Å; A67-L71 WeakPolarHBondContact O-CB 3.36Å; A67-L71 PolarHBondContact O-N 3.49Å
68	C	79.8	Confident	74.4	Confident	52 Å²	52	116.3 Å²	116.3	35%	0.351	59%	0.592	S	S	.	*	H	α-helix	trans	-61.3	-45.7	175.2	-73.8	0	0	0	0	112.3	F64 L65 S70 L71 Q72	F64-C68 VanDerWaalsContact CZ-SG 3.54Å; F64-C68 PolarHBondContact O-N 3.48Å; F64-C68 PolarHBondContact O-SG 3.39Å; F64-C68 VanDerWaalsContact O-SG 3.38Å; L65-C68 PolarHBondContact O-N 3.04Å; C68-S70 VanDerWaalsContact C-N 3.33Å; C68-S70 PolarHBondContact O-N 3.26Å; C68-L71 PolarHBondContact O-N 2.95Å; C68-Q72 WeakPolarHBondContact O-CB 3.39Å; C68-Q72 PolarHBondContact O-N 3.11Å
69	K	82.8	Confident	74.2	Confident	146 Å²	146	114.1 Å²	114.1	64%	0.635	59%	0.592	S	S	*	*	H	α-helix	trans	-62.3	-39.6	176.7	-77.9	179	179.3	178.3	0	112.4	L65 S66 T73	L65-K69 WeakPolarHBondContact O-CG 3.36Å; L65-K69 PolarHBondContact O-N 3.21Å; S66-K69 PolarHBondContact O-N 3.43Å; K69-T73 WeakPolarHBondContact O-CB 3.43Å; K69-T73 PolarHBondContact O-N 2.7Å; K69-T73 PolarHBondContact O-OG1 3.06Å
70	S	81.6	Confident	73.6	Confident	71 Å²	71	114.5 Å²	114.5	50%	0.497	60%	0.598	S	S	.	*	H	α-helix	trans	-63	-45.4	175.3	177.7	0	0	0	0	111.4	S66 A67 C68 T73 R74	S66-S70 WeakPolarHBondContact O-CB 3.46Å; S66-S70 PolarHBondContact O-N 2.98Å; A67-S70 PolarHBondContact O-N 3.16Å; C68-S70 VanDerWaalsContact C-N 3.33Å; C68-S70 PolarHBondContact O-N 3.26Å; S70-T73 PolarHBondContact O-N 3.45Å; S70-R74 WeakPolarHBondContact O-CG 3.39Å; S70-R74 PolarHBondContact O-N 3.38Å
71	L	76	Confident	72.1	Confident	111 Å²	111	113.2 Å²	113.2	58%	0.581	60%	0.604	S	S	*	*	H	α-helix	trans	-67.2	-39.8	178.7	-163.4	73.8	0	0	0	112.4	A67 C68 R74 Q75	A67-L71 WeakPolarHBondContact O-CB 3.36Å; A67-L71 PolarHBondContact O-N 3.49Å; C68-L71 PolarHBondContact O-N 2.95Å; L71-R74 PolarHBondContact O-N 3.31Å; L71-R74 VanDerWaalsContact O-N 3.15Å; L71-Q75 PolarHBondContact O-N 3.46Å; L71-Q75 VanDerWaalsContact O-N 3.09Å
72	Q	73.6	Confident	70.9	Confident	135 Å²	135	118.1 Å²	118.1	63%	0.631	62%	0.618	S	S	*	*	H	α-helix	trans	-65.2	-39.8	178	-169	169	16.7	0	0	111.9	C68 R74 Q75	C68-Q72 WeakPolarHBondContact O-CB 3.39Å; C68-Q72 PolarHBondContact O-N 3.11Å; Q72-R74 PolarHBondContact O-N 2.99Å; Q72-Q75 PolarHBondContact O-N 3.1Å; Q72-Q75 VanDerWaalsContact O-N 3.12Å
73	T	68.7	Low	69.5	Low	105 Å²	105	116 Å²	116	64%	0.644	62%	0.617	S	S	*	*	H	α-helix	trans	-61.7	-34.5	173.4	-54.3	0	0	0	0	111.8	K69 S70	K69-T73 WeakPolarHBondContact O-CB 3.43Å; K69-T73 PolarHBondContact O-N 2.7Å; K69-T73 PolarHBondContact O-OG1 3.06Å; S70-T73 PolarHBondContact O-N 3.45Å
74	R	66.9	Low	68.2	Low	210 Å²	210	115 Å²	115	79%	0.792	62%	0.623	S	S	*	*	H	α-helix	trans	-76.5	-18.3	176.1	-68	178.5	76.2	-166.7	3.8	113.8	S70 L71 Q72	S70-R74 WeakPolarHBondContact O-CG 3.39Å; S70-R74 PolarHBondContact O-N 3.38Å; L71-R74 PolarHBondContact O-N 3.31Å; L71-R74 VanDerWaalsContact O-N 3.15Å; Q72-R74 PolarHBondContact O-N 2.99Å
75	Q	63	Low	66.8	Low	110 Å²	110	114.5 Å²	114.5	51%	0.514	63%	0.626	S	S	.	*	T	Hydrogen-bonded Turn	trans	-101.9	10.9	-174.2	-150.7	177.7	25.4	0	0	114	L71 Q72 G77 I78	L71-Q75 PolarHBondContact O-N 3.46Å; L71-Q75 VanDerWaalsContact O-N 3.09Å; Q72-Q75 PolarHBondContact O-N 3.1Å; Q72-Q75 VanDerWaalsContact O-N 3.12Å; Q75-G77 PolarHBondContact O-N 3Å; Q75-I78 PolarHBondContact O-N 2.88Å
76	N	56.1	Low	65.3	Low	150 Å²	150	120.4 Å²	120.4	80%	0.802	64%	0.643	S	S	*	*	T	Hydrogen-bonded Turn	trans	-61.2	10.9	179.7	-97.2	-5.5	0	0	0	116.1
77	G	57.4	Low	64	Low	72 Å²	72	120.1 Å²	120.1	74%	0.742	65%	0.645	S	S	*	*	T	Hydrogen-bonded Turn	trans	-122.5	-3.5	-179	0	0	0	0	0	116.5	Q75	Q75-G77 PolarHBondContact O-N 3Å
78	I	54.1	Low	62.8	Low	122 Å²	122	121.7 Å²	121.7	63%	0.626	65%	0.648	S	S	*	*			trans	-126.1	98.5	-176.3	-56.4	171.1	0	0	0	109.2	Q75 T80	Q75-I78 PolarHBondContact O-N 2.88Å; I78-T80 HydrophobicContact CG2-CG2 4.03Å; I78-T80 PolarHBondContact O-N 3.21Å
79	Q	59.6	Low	61.9	Low	194 Å²	194	128.6 Å²	128.6	91%	0.907	67%	0.667	S	S	*	*			trans	-60.6	98.5	166	-66.7	-174.2	46.3	0	0	108.3
80	T	55.2	Low	60.7	Low	107 Å²	107	126.6 Å²	126.6	66%	0.656	66%	0.66	S	S	*	*			trans	-81.2	128.7	170.6	62.8	0	0	0	0	108.6	I78	I78-T80 HydrophobicContact CG2-CG2 4.03Å; I78-T80 PolarHBondContact O-N 3.21Å
81	N	49.7	Very low	59.7	Low	143 Å²	143	129.9 Å²	129.9	77%	0.765	66%	0.661	S	S	*	*			trans	-56	165.2	-166.9	-80.7	-54.1	0	0	0	114.2	P83	N81-P83 HydrophobicContact CB-CG 4.35Å; N81-P83 WeakPolarHBondContact O-CD 3.46Å
82	K	57.5	Low	59.4	Low	182 Å²	182	127.4 Å²	127.4	79%	0.791	65%	0.654	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.2	28.6	178.3	-64.8	172.3	173.3	169	0	118.2
83	P	54.5	Low	59.8	Low	94 Å²	94	125.7 Å²	125.7	61%	0.61	65%	0.646	S	S	*	*	T	Hydrogen-bonded Turn	trans	-74.1	-29.9	170.7	-18.6	32	0	0	0	114.3	N81 L85 R86	N81-P83 HydrophobicContact CB-CG 4.35Å; N81-P83 WeakPolarHBondContact O-CD 3.46Å; P83-L85 VanDerWaalsContact C-N 3.31Å; P83-L85 PolarHBondContact O-N 2.88Å; P83-R86 PolarHBondContact O-N 3.12Å
84	A	56.1	Low	60.7	Low	69 Å²	69	121.2 Å²	121.2	57%	0.57	62%	0.617	S	S	*	*	H	α-helix	trans	-64.1	-33.3	-172.4	0	0	0	0	0	113.4	R86 A87 V88	A84-R86 PolarHBondContact O-N 3.34Å; A84-A87 PolarHBondContact O-N 3.38Å; A84-V88 VanDerWaalsContact O-CG2 3.31Å; A84-V88 WeakPolarHBondContact O-CG2 3.08Å; A84-V88 PolarHBondContact O-N 3.06Å; A84-V88 VanDerWaalsContact O-N 3.08Å
85	L	55	Low	61.6	Low	125 Å²	125	114.9 Å²	114.9	65%	0.654	60%	0.602	S	S	*	*	H	α-helix	trans	-66.2	-34	-179.3	-75.1	166.3	0	0	0	112.9	P83 R89	P83-L85 VanDerWaalsContact C-N 3.31Å; P83-L85 PolarHBondContact O-N 2.88Å; L85-R89 VanDerWaalsContact O-CB 3.23Å; L85-R89 WeakPolarHBondContact O-CB 2.97Å; L85-R89 PolarHBondContact O-N 3.42Å
86	R	54.3	Low	62.9	Low	201 Å²	201	113.9 Å²	113.9	76%	0.758	60%	0.6	S	S	*	*	H	α-helix	trans	-71.8	-40.3	177.8	-77.2	-167.9	173.8	-176.3	-0.5	112	P83 A84 R89 Q90	P83-R86 PolarHBondContact O-N 3.12Å; A84-R86 PolarHBondContact O-N 3.34Å; R86-R89 PolarHBondContact O-N 2.79Å; R86-Q90 WeakPolarHBondContact O-CB 3.42Å; R86-Q90 WeakPolarHBondContact O-CG 3.47Å; R86-Q90 PolarHBondContact O-N 2.77Å
87	A	57.5	Low	64.5	Low	63 Å²	63	111 Å²	111	52%	0.521	58%	0.582	S	S	.	*	H	α-helix	trans	-65.2	-39.8	176.2	0	0	0	0	0	112	A84 R91	A84-A87 PolarHBondContact O-N 3.38Å; A87-R91 WeakPolarHBondContact O-CB 3.35Å; A87-R91 PolarHBondContact O-N 2.88Å; A87-R91 VanDerWaalsContact O-N 3.1Å
88	V	60.1	Low	66.1	Low	94 Å²	94	108 Å²	108	57%	0.57	55%	0.551	S	S	*	*	H	α-helix	trans	-67.2	-43	174.5	173.9	0	0	0	0	111.6	A84 Q90 R91 S92	A84-V88 VanDerWaalsContact O-CG2 3.31Å; A84-V88 WeakPolarHBondContact O-CG2 3.08Å; A84-V88 PolarHBondContact O-N 3.06Å; A84-V88 VanDerWaalsContact O-N 3.08Å; V88-Q90 PolarHBondContact O-N 3.26Å; V88-R91 VanDerWaalsContact O-CB 3.31Å; V88-R91 WeakPolarHBondContact O-CB 3.21Å; V88-R91 PolarHBondContact O-N 2.63Å; V88-S92 PolarHBondContact O-N 3.29Å
89	R	60.5	Low	68	Low	196 Å²	196	109.9 Å²	109.9	74%	0.74	56%	0.555	S	S	*	*	H	α-helix	trans	-65	-39	179.8	-156.8	176.9	-155.4	177.2	5.7	112.3	L85 R86 S92	L85-R89 VanDerWaalsContact O-CB 3.23Å; L85-R89 WeakPolarHBondContact O-CB 2.97Å; L85-R89 PolarHBondContact O-N 3.42Å; R86-R89 PolarHBondContact O-N 2.79Å; R89-S92 WeakPolarHBondContact O-CB 3.01Å; R89-S92 PolarHBondContact O-N 2.85Å
90	Q	58.2	Low	69.6	Low	104 Å²	104	108 Å²	108	49%	0.486	54%	0.539	S	S	.	.	H	α-helix	trans	-73.2	-26.4	174.9	-70.5	-173.4	4.6	0	0	113.8	R86 V88 S92	R86-Q90 WeakPolarHBondContact O-CB 3.42Å; R86-Q90 WeakPolarHBondContact O-CG 3.47Å; R86-Q90 PolarHBondContact O-N 2.77Å; V88-Q90 PolarHBondContact O-N 3.26Å; Q90-S92 VanDerWaalsContact C-N 3.27Å
91	R	60.8	Low	71.5	Confident	140 Å²	140	103 Å²	103	53%	0.528	51%	0.509	S	S	.	.	H	α-helix	trans	-65	-34.9	167.8	-114.7	175.3	162.5	-175.2	-6.1	111	A87 V88 E93 T95 L168	A87-R91 WeakPolarHBondContact O-CB 3.35Å; A87-R91 PolarHBondContact O-N 2.88Å; A87-R91 VanDerWaalsContact O-N 3.1Å; V88-R91 VanDerWaalsContact O-CB 3.31Å; V88-R91 WeakPolarHBondContact O-CB 3.21Å; V88-R91 PolarHBondContact O-N 2.63Å; R91-E93 PolarHBondContact O-N 2.67Å; R91-T95 WeakPolarHBondContact O-CB 3.28Å; R91-T95 PolarHBondContact O-N 3.2Å; R91-T95 PolarHBondContact O-OG1 3.04Å; R91-L168 HydrophobicContact CG-CD1 4.31Å
92	S	69.4	Low	73.6	Confident	60 Å²	60	97.3 Å²	97.3	42%	0.42	48%	0.483	S	S	.	.	H	α-helix	trans	-60.4	-41.1	176.8	-169.3	0	0	0	0	112.5	V88 R89 Q90 T95 L96	V88-S92 PolarHBondContact O-N 3.29Å; R89-S92 WeakPolarHBondContact O-CB 3.01Å; R89-S92 PolarHBondContact O-N 2.85Å; Q90-S92 VanDerWaalsContact C-N 3.27Å; S92-T95 PolarHBondContact O-N 3.05Å; S92-L96 WeakPolarHBondContact O-CB 3.35Å; S92-L96 PolarHBondContact O-N 3.24Å
93	E	81.9	Confident	75.4	Confident	99 Å²	99	95.3 Å²	95.3	46%	0.463	48%	0.475	S	S	.	.	H	α-helix	trans	-65.5	-51.7	-173.5	-66.5	-60.1	133.9	0	0	113	R91 T95 L96 M97	R91-E93 PolarHBondContact O-N 2.67Å; E93-T95 VanDerWaalsContact C-N 3.35Å; E93-T95 PolarHBondContact O-N 3.04Å; E93-L96 PolarHBondContact O-N 3.49Å; E93-M97 PolarHBondContact O-N 2.99Å
94	F	86.6	Confident	77.3	Confident	11 Å²	11	93.3 Å²	93.3	5%	0.048	46%	0.459	C	S	.	.	H	α-helix	trans	-58.9	-47.8	175.2	171.7	-92.2	0	0	0	110.9	L96 M97 A98 L153 F156 V157 S172 I175 V176	F94-L96 VanDerWaalsContact C-N 3.31Å; F94-L96 PolarHBondContact O-N 2.98Å; F94-M97 PolarHBondContact O-N 3.43Å; F94-A98 HydrophobicContact CE1-CB 4.4Å; F94-A98 WeakPolarHBondContact O-CB 3.42Å; F94-A98 PolarHBondContact O-N 2.95Å; F94-L153 HydrophobicContact CD2-CD1 3.32Å; F94-L153 HydrophobicContact CD2-CG 4.02Å; F94-L153 HydrophobicContact CE2-CD1 3.41Å; F94-L153 VanDerWaalsContact CE2-CD1 3.41Å; F94-L153 HydrophobicContact CE2-CD2 3.92Å; F94-L153 HydrophobicContact CE2-CG 3.57Å; F94-L153 HydrophobicContact CG-CD1 4.25Å; F94-L153 HydrophobicContact CZ-CD1 4.38Å; F94-L153 HydrophobicContact CZ-CD2 4.31Å; F94-L153 HydrophobicContact CZ-CG 4.43Å; F94-F156 HydrophobicContact CB-CD1 4.35Å; F94-F156 HydrophobicContact CB-CE1 3.95Å; F94-F156 HydrophobicContact CD2-CD1 4.2Å; F94-V157 HydrophobicContact CD2-CG2 3.75Å; F94-V157 HydrophobicContact CE2-CG2 3.33Å; F94-V157 HydrophobicContact CZ-CG2 4.25Å; F94-S172 WeakPolarHBondContact CZ-O 3.5Å; F94-I175 HydrophobicContact CE1-CB 4.38Å; F94-I175 HydrophobicContact CE1-CD1 3.92Å; F94-I175 HydrophobicContact CE1-CG2 4.35Å; F94-I175 HydrophobicContact CZ-CB 4.14Å; F94-I175 HydrophobicContact CZ-CG2 4.09Å; F94-V176 HydrophobicContact CE2-CG2 4.09Å; F94-V176 HydrophobicContact CZ-CG2 4.29Å
95	T	87.3	Confident	79.1	Confident	77 Å²	77	90.3 Å²	90.3	47%	0.472	43%	0.433	S	S	.	.	H	α-helix	trans	-64.5	-35.4	-179.3	-61.1	0	0	0	0	112	R91 S92 E93 K99	R91-T95 WeakPolarHBondContact O-CB 3.28Å; R91-T95 PolarHBondContact O-N 3.2Å; R91-T95 PolarHBondContact O-OG1 3.04Å; S92-T95 PolarHBondContact O-N 3.05Å; E93-T95 VanDerWaalsContact C-N 3.35Å; E93-T95 PolarHBondContact O-N 3.04Å; T95-K99 WeakPolarHBondContact O-CB 3.26Å; T95-K99 PolarHBondContact O-N 3.03Å
96	L	89.2	Confident	80.9	Confident	89 Å²	89	88 Å²	88	47%	0.466	43%	0.428	S	S	.	.	H	α-helix	trans	-69.1	-44	177.1	-166.3	100.2	0	0	0	111.1	S92 E93 F94 K99 R100	S92-L96 WeakPolarHBondContact O-CB 3.35Å; S92-L96 PolarHBondContact O-N 3.24Å; E93-L96 PolarHBondContact O-N 3.49Å; F94-L96 VanDerWaalsContact C-N 3.31Å; F94-L96 PolarHBondContact O-N 2.98Å; L96-K99 PolarHBondContact O-N 3.09Å; L96-R100 PolarHBondContact O-N 2.88Å
97	M	90.5	Very high	82.8	Confident	88 Å²	88	82.1 Å²	82.1	43%	0.433	41%	0.411	S	S	.	.	H	α-helix	trans	-62	-49.8	174.1	-75	-173.5	164.7	0	0	111.2	E93 F94 K99 R100 I101 L153	E93-M97 PolarHBondContact O-N 2.99Å; F94-M97 PolarHBondContact O-N 3.43Å; M97-K99 VanDerWaalsContact C-N 3.29Å; M97-K99 PolarHBondContact O-N 2.94Å; M97-R100 WeakPolarHBondContact O-CB 3.47Å; M97-R100 PolarHBondContact O-N 3.21Å; M97-R100 VanDerWaalsContact O-N 3.12Å; M97-I101 WeakPolarHBondContact O-CG1 3.47Å; M97-I101 PolarHBondContact O-N 3.33Å; M97-L153 HydrophobicContact CB-CD1 3.97Å
98	A	91.3	Very high	84.5	Confident	11 Å²	11	79.2 Å²	79.2	9%	0.091	39%	0.387	C	S	.	.	H	α-helix	trans	-59	-39.8	176.9	0	0	0	0	0	112.2	F94 G102 L153 I175 L179	F94-A98 HydrophobicContact CE1-CB 4.4Å; F94-A98 WeakPolarHBondContact O-CB 3.42Å; F94-A98 PolarHBondContact O-N 2.95Å; A98-G102 PolarHBondContact O-N 3.44Å; A98-L153 HydrophobicContact CB-CD2 4.17Å; A98-I175 HydrophobicContact CB-CG2 3.93Å; A98-L179 HydrophobicContact CB-CD1 4.45Å
99	K	92.1	Very high	85.9	Confident	161 Å²	161	77.7 Å²	77.7	70%	0.7	37%	0.373	S	S	*	.	H	α-helix	trans	-64.7	-41.7	175.2	-178.6	179.8	178.9	-179.9	0	112.1	T95 L96 M97 G102 K103	T95-K99 WeakPolarHBondContact O-CB 3.26Å; T95-K99 PolarHBondContact O-N 3.03Å; L96-K99 PolarHBondContact O-N 3.09Å; M97-K99 VanDerWaalsContact C-N 3.29Å; M97-K99 PolarHBondContact O-N 2.94Å; K99-G102 PolarHBondContact O-N 3.23Å; K99-K103 PolarHBondContact O-N 2.97Å
100	R	94.3	Very high	87.2	Confident	153 Å²	153	71.1 Å²	71.1	58%	0.577	36%	0.36	S	S	*	.	H	α-helix	trans	-62.7	-50.8	176.7	-175.7	-176.2	-65	-160.3	-0.6	110.7	L96 M97 G102 K103 D104	L96-R100 PolarHBondContact O-N 2.88Å; M97-R100 WeakPolarHBondContact O-CB 3.47Å; M97-R100 PolarHBondContact O-N 3.21Å; M97-R100 VanDerWaalsContact O-N 3.12Å; R100-G102 VanDerWaalsContact C-N 3.27Å; R100-G102 PolarHBondContact O-N 2.93Å; R100-K103 WeakPolarHBondContact O-CB 3.34Å; R100-K103 PolarHBondContact O-N 3.39Å; R100-D104 PolarHBondContact O-N 2.98Å
101	I	95.8	Very high	88.7	Confident	3 Å²	3	69.3 Å²	69.3	2%	0.015	35%	0.351	C	S	.	.	H	α-helix	trans	-56.6	-44.8	176.6	-65.3	163.7	0	0	0	110.2	M97 K103 D104 L105 L146 Q149 I150 L153 L179	M97-I101 WeakPolarHBondContact O-CG1 3.47Å; M97-I101 PolarHBondContact O-N 3.33Å; I101-K103 VanDerWaalsContact C-N 3.33Å; I101-K103 PolarHBondContact O-N 2.99Å; I101-D104 PolarHBondContact O-N 2.9Å; I101-L105 WeakPolarHBondContact O-CB 3.28Å; I101-L105 PolarHBondContact O-N 3.18Å; I101-L146 HydrophobicContact CG2-CD2 3.97Å; I101-Q149 HydrophobicContact CD1-CB 3.89Å; I101-Q149 HydrophobicContact CG1-CB 3.81Å; I101-I150 HydrophobicContact CD1-CG1 4.38Å; I101-I150 HydrophobicContact CG2-CD1 4.1Å; I101-I150 HydrophobicContact CG2-CG1 3.76Å; I101-L153 HydrophobicContact CD1-CB 4.25Å; I101-L153 HydrophobicContact CD1-CD2 3.93Å; I101-L179 HydrophobicContact CB-CD1 4.4Å; I101-L179 HydrophobicContact CG2-CD1 4.05Å; I101-L179 HydrophobicContact CG2-CD2 4.22Å
102	G	93.7	Very high	90.1	Very high	23 Å²	23	62.9 Å²	62.9	24%	0.237	33%	0.327	C	S	.	.	H	α-helix	trans	-59.7	-40.4	176.6	0	0	0	0	0	113.4	A98 K99 R100 S106	A98-G102 PolarHBondContact O-N 3.44Å; K99-G102 PolarHBondContact O-N 3.23Å; R100-G102 VanDerWaalsContact C-N 3.27Å; R100-G102 PolarHBondContact O-N 2.93Å; G102-S106 PolarHBondContact O-N 3.28Å; G102-S106 PolarHBondContact O-OG 2.8Å
103	K	94.1	Very high	90.8	Very high	140 Å²	140	66.1 Å²	66.1	61%	0.609	34%	0.335	S	S	*	.	H	α-helix	trans	-67.1	-46.6	175.8	-175.5	-177.6	178	-176.1	0	111.7	K99 R100 I101 L105 S106 N107	K99-K103 PolarHBondContact O-N 2.97Å; R100-K103 WeakPolarHBondContact O-CB 3.34Å; R100-K103 PolarHBondContact O-N 3.39Å; I101-K103 VanDerWaalsContact C-N 3.33Å; I101-K103 PolarHBondContact O-N 2.99Å; K103-L105 VanDerWaalsContact C-N 3.31Å; K103-L105 PolarHBondContact O-N 3.12Å; K103-S106 PolarHBondContact O-N 3.39Å; K103-N107 VanDerWaalsContact O-CG 3.27Å; K103-N107 PolarHBondContact O-N 3.04Å; K103-N107 PolarHBondContact O-ND2 3.21Å
104	D	95.6	Very high	91	Very high	52 Å²	52	66 Å²	66	28%	0.278	33%	0.333	S	S	.	.	H	α-helix	trans	-62.2	-43	-179.9	-68.2	-12.5	0	0	0	110.2	R100 I101 S106 N107 T108 L146	R100-D104 PolarHBondContact O-N 2.98Å; I101-D104 PolarHBondContact O-N 2.9Å; D104-S106 PolarHBondContact O-N 2.81Å; D104-N107 WeakPolarHBondContact O-CB 3.39Å; D104-N107 PolarHBondContact O-N 3.01Å; D104-T108 PolarHBondContact O-N 2.82Å; D104-T108 PolarHBondContact O-OG1 3.08Å; D104-L146 HydrophobicContact CB-CD2 3.76Å
105	L	93.3	Very high	91	Very high	6 Å²	6	65.5 Å²	65.5	3%	0.031	33%	0.331	C	S	.	.	H	α-helix	trans	-58.4	-47.2	173.7	-173	78	0	0	0	112.1	I101 K103 N107 T108 F109 L146 L179 K182 L183 M186	I101-L105 WeakPolarHBondContact O-CB 3.28Å; I101-L105 PolarHBondContact O-N 3.18Å; K103-L105 VanDerWaalsContact C-N 3.31Å; K103-L105 PolarHBondContact O-N 3.12Å; L105-N107 VanDerWaalsContact C-N 3.32Å; L105-N107 PolarHBondContact O-N 3.38Å; L105-T108 PolarHBondContact O-N 3.05Å; L105-F109 HydrophobicContact CD1-CE2 4.19Å; L105-F109 HydrophobicContact CD2-CE2 4.34Å; L105-F109 HydrophobicContact CG-CD2 4.06Å; L105-F109 HydrophobicContact CG-CE2 3.93Å; L105-F109 WeakPolarHBondContact O-CD2 3.48Å; L105-F109 PolarHBondContact O-N 3.21Å; L105-L146 HydrophobicContact CB-CD1 4.43Å; L105-L146 HydrophobicContact CB-CD2 4.29Å; L105-L146 HydrophobicContact CD1-CD1 4.02Å; L105-L179 HydrophobicContact CD2-CD2 4.35Å; L105-K182 HydrophobicContact CD2-CB 3.65Å; L105-K182 HydrophobicContact CD2-CD 3.88Å; L105-K182 HydrophobicContact CD2-CG 4.43Å; L105-L183 HydrophobicContact CD1-CB 4.35Å; L105-L183 HydrophobicContact CD1-CD1 4.22Å; L105-M186 HydrophobicContact CD1-CE 3.4Å; L105-M186 VanDerWaalsContact CD1-CE 3.4Å; L105-M186 HydrophobicContact CD1-SD 4.2Å; L105-M186 HydrophobicContact CG-CE 3.85Å; L105-M186 WeakPolarHBondContact O-CE 3.33Å
106	S	91.9	Very high	90.8	Very high	77 Å²	77	63.1 Å²	63.1	54%	0.538	32%	0.317	S	S	.	.	H	α-helix	trans	-61.3	-40	175.6	-69.5	0	0	0	0	112.6	G102 K103 D104 F109 A110	G102-S106 PolarHBondContact O-N 3.28Å; G102-S106 PolarHBondContact O-OG 2.8Å; K103-S106 PolarHBondContact O-N 3.39Å; D104-S106 PolarHBondContact O-N 2.81Å; S106-F109 PolarHBondContact O-N 3.44Å; S106-A110 PolarHBondContact O-N 3.44Å; S106-A110 VanDerWaalsContact O-N 3.14Å
107	N	94.3	Very high	90.6	Very high	77 Å²	77	63.8 Å²	63.8	41%	0.412	32%	0.32	S	S	.	.	H	α-helix	trans	-64.9	-42.5	176.9	-67.9	-24.3	0	0	0	111.6	K103 D104 L105 A110 K111	K103-N107 VanDerWaalsContact O-CG 3.27Å; K103-N107 PolarHBondContact O-N 3.04Å; K103-N107 PolarHBondContact O-ND2 3.21Å; D104-N107 WeakPolarHBondContact O-CB 3.39Å; D104-N107 PolarHBondContact O-N 3.01Å; L105-N107 VanDerWaalsContact C-N 3.32Å; L105-N107 PolarHBondContact O-N 3.38Å; N107-A110 PolarHBondContact O-N 2.95Å; N107-K111 WeakPolarHBondContact O-CG 3.32Å; N107-K111 PolarHBondContact O-N 3.26Å; N107-K111 VanDerWaalsContact O-N 3.17Å
108	T	94.1	Very high	90.3	Very high	2 Å²	2	60.8 Å²	60.8	1%	0.012	31%	0.305	C	S	.	.	H	α-helix	trans	-67.7	-36.2	177.7	-50.5	0	0	0	0	111.5	D104 L105 A110 K111 L112 I139 D142 I143 M186	D104-T108 PolarHBondContact O-N 2.82Å; D104-T108 PolarHBondContact O-OG1 3.08Å; L105-T108 PolarHBondContact O-N 3.05Å; T108-A110 VanDerWaalsContact C-N 3.35Å; T108-A110 PolarHBondContact O-N 3.34Å; T108-K111 PolarHBondContact O-N 2.9Å; T108-L112 WeakPolarHBondContact O-CB 3.44Å; T108-L112 PolarHBondContact O-N 3.16Å; T108-I139 HydrophobicContact CG2-CG1 4.38Å; T108-I139 HydrophobicContact CG2-CG2 4.1Å; T108-D142 HydrophobicContact CG2-CB 3.66Å; T108-D142 VanDerWaalsContact OG1-CB 3.29Å; T108-D142 WeakPolarHBondContact OG1-CB 3.45Å; T108-D142 PolarHBondContact OG1-OD2 3.4Å; T108-I143 HydrophobicContact CG2-CG1 4.42Å; T108-M186 HydrophobicContact CG2-CE 4.17Å; T108-M186 HydrophobicContact CG2-SD 3.49Å; T108-M186 WeakPolarHBondContact CG2-SD 3.43Å
109	F	89.4	Confident	89.8	Confident	63 Å²	63	60.4 Å²	60.4	28%	0.276	30%	0.302	S	S	.	.	H	α-helix	trans	-59	-43.9	172	-93.8	-62.9	0	0	0	112	L105 S106 K111 L112 E113 K182 M186	L105-F109 HydrophobicContact CD1-CE2 4.19Å; L105-F109 HydrophobicContact CD2-CE2 4.34Å; L105-F109 HydrophobicContact CG-CD2 4.06Å; L105-F109 HydrophobicContact CG-CE2 3.93Å; L105-F109 WeakPolarHBondContact O-CD2 3.48Å; L105-F109 PolarHBondContact O-N 3.21Å; S106-F109 PolarHBondContact O-N 3.44Å; F109-K111 VanDerWaalsContact C-N 3.34Å; F109-K111 PolarHBondContact O-N 2.97Å; F109-L112 WeakPolarHBondContact O-CB 3.32Å; F109-L112 PolarHBondContact O-N 3.46Å; F109-E113 PolarHBondContact O-N 3.04Å; F109-K182 HydrophobicContact CE2-CB 4.48Å; F109-M186 HydrophobicContact CB-CE 4.04Å; F109-M186 HydrophobicContact CD1-CB 4.42Å; F109-M186 HydrophobicContact CD1-CE 3.92Å; F109-M186 HydrophobicContact CD1-CG 4.28Å; F109-M186 HydrophobicContact CD2-CE 3.12Å; F109-M186 HydrophobicContact CE1-CB 3.73Å; F109-M186 HydrophobicContact CE1-CE 4.15Å; F109-M186 HydrophobicContact CE1-CG 4.06Å; F109-M186 HydrophobicContact CE2-CB 4.17Å; F109-M186 HydrophobicContact CE2-CE 3.4Å; F109-M186 HydrophobicContact CG-CE 3.41Å; F109-M186 VanDerWaalsContact CG-CE 3.41Å; F109-M186 HydrophobicContact CZ-CB 3.58Å; F109-M186 HydrophobicContact CZ-CE 3.91Å; F109-M186 HydrophobicContact CZ-CG 4.25Å
110	A	86.6	Confident	89	Confident	57 Å²	57	59.3 Å²	59.3	47%	0.471	30%	0.298	S	S	.	.	H	α-helix	trans	-63.3	-39.4	177.6	0	0	0	0	0	112.3	S106 N107 T108 E113 K114	S106-A110 PolarHBondContact O-N 3.44Å; S106-A110 VanDerWaalsContact O-N 3.14Å; N107-A110 PolarHBondContact O-N 2.95Å; T108-A110 VanDerWaalsContact C-N 3.35Å; T108-A110 PolarHBondContact O-N 3.34Å; A110-E113 PolarHBondContact O-N 2.86Å; A110-K114 PolarHBondContact O-N 3.08Å; A110-K114 VanDerWaalsContact O-N 3.12Å
111	K	90.9	Very high	87.9	Confident	66 Å²	66	58.3 Å²	58.3	29%	0.287	29%	0.294	S	S	.	.	H	α-helix	trans	-64.6	-41.9	173.5	-65.1	175.3	-165.8	166.5	0	111.5	N107 T108 F109 K114 L115 L135 I138 I139 D142	N107-K111 WeakPolarHBondContact O-CG 3.32Å; N107-K111 PolarHBondContact O-N 3.26Å; N107-K111 VanDerWaalsContact O-N 3.17Å; T108-K111 PolarHBondContact O-N 2.9Å; F109-K111 VanDerWaalsContact C-N 3.34Å; F109-K111 PolarHBondContact O-N 2.97Å; K111-K114 WeakPolarHBondContact O-CB 3.46Å; K111-K114 PolarHBondContact O-N 3.5Å; K111-L115 PolarHBondContact O-N 3.38Å; K111-L135 HydrophobicContact CB-CD2 4.23Å; K111-I138 HydrophobicContact CD-CG2 3.69Å; K111-I138 VanDerWaalsContact NZ-CG2 3.29Å; K111-I139 HydrophobicContact CB-CD1 4.11Å; K111-I139 HydrophobicContact CB-CG1 3.94Å; K111-D142 IonicContact NZ-OD1 3.28Å; K111-D142 IonicContact NZ-OD2 2.9Å; K111-D142 PolarHBondContact NZ-OD2 2.83Å
112	L	89.9	Confident	86.4	Confident	5 Å²	5	66.4 Å²	66.4	3%	0.026	33%	0.329	C	S	.	.	H	α-helix	trans	-64.4	-39.4	177.9	177	59.5	0	0	0	112.1	T108 F109 L115 T116 I139 M186 D189 F190 V193	T108-L112 WeakPolarHBondContact O-CB 3.44Å; T108-L112 PolarHBondContact O-N 3.16Å; F109-L112 WeakPolarHBondContact O-CB 3.32Å; F109-L112 PolarHBondContact O-N 3.46Å; L112-L115 PolarHBondContact O-N 2.91Å; L112-T116 WeakPolarHBondContact O-CB 3.25Å; L112-T116 PolarHBondContact O-N 3.11Å; L112-T116 PolarHBondContact O-OG1 3.27Å; L112-I139 HydrophobicContact CB-CD1 4.17Å; L112-I139 HydrophobicContact CD1-CD1 4.41Å; L112-M186 HydrophobicContact CD2-CG 3.7Å; L112-M186 WeakPolarHBondContact CD2-O 3.18Å; L112-D189 HydrophobicContact CD2-CB 3.77Å; L112-F190 HydrophobicContact CD1-CB 3.78Å; L112-F190 HydrophobicContact CD1-CD2 3.79Å; L112-F190 HydrophobicContact CD1-CG 4.22Å; L112-F190 HydrophobicContact CD2-CB 4.25Å; L112-V193 HydrophobicContact CD1-CG2 4.38Å
113	E	83.4	Confident	84.8	Confident	128 Å²	128	67.1 Å²	67.1	60%	0.598	33%	0.33	S	S	*	.	H	α-helix	trans	-61.7	-45.6	173.7	-174.5	176.6	-165.6	0	0	111	F109 A110 L115 T116 I117	F109-E113 PolarHBondContact O-N 3.04Å; A110-E113 PolarHBondContact O-N 2.86Å; E113-L115 PolarHBondContact O-N 3.5Å; E113-T116 VanDerWaalsContact O-CB 3.31Å; E113-T116 WeakPolarHBondContact O-CB 3.49Å; E113-T116 PolarHBondContact O-N 2.93Å; E113-T116 VanDerWaalsContact O-N 3.15Å; E113-I117 HydrophobicContact CG-CD1 4.42Å; E113-I117 WeakPolarHBondContact O-CG1 3.3Å; E113-I117 PolarHBondContact O-N 3.38Å
114	K	85.8	Confident	83	Confident	97 Å²	97	65.1 Å²	65.1	42%	0.422	33%	0.325	S	S	.	.	H	α-helix	trans	-59	-45.8	174.1	-172.5	-179.3	177.1	-167.1	0	111.9	A110 K111 T116 I117 L118 E131 L135	A110-K114 PolarHBondContact O-N 3.08Å; A110-K114 VanDerWaalsContact O-N 3.12Å; K111-K114 WeakPolarHBondContact O-CB 3.46Å; K111-K114 PolarHBondContact O-N 3.5Å; K114-T116 VanDerWaalsContact C-N 3.31Å; K114-T116 PolarHBondContact O-N 2.88Å; K114-I117 PolarHBondContact O-N 3.44Å; K114-L118 WeakPolarHBondContact O-CG 3.45Å; K114-L118 PolarHBondContact O-N 2.89Å; K114-L118 VanDerWaalsContact O-N 3.08Å; K114-E131 WeakPolarHBondContact CE-OE1 3.47Å; K114-E131 IonicContact NZ-OE1 2.82Å; K114-E131 PolarHBondContact NZ-OE1 3.2Å; K114-L135 HydrophobicContact CD-CD1 4.15Å; K114-L135 HydrophobicContact CG-CD1 4.15Å
115	L	88.3	Confident	81.1	Confident	1 Å²	1	72.2 Å²	72.2	1%	0.005	35%	0.354	C	S	.	.	H	α-helix	trans	-61	-40.7	175.4	-179.2	66.8	0	0	0	111.4	K111 L112 E113 I117 L118 A119 I132 L135 I139 F190 V193	K111-L115 PolarHBondContact O-N 3.38Å; L112-L115 PolarHBondContact O-N 2.91Å; E113-L115 PolarHBondContact O-N 3.5Å; L115-I117 VanDerWaalsContact C-N 3.32Å; L115-I117 PolarHBondContact O-N 2.7Å; L115-L118 PolarHBondContact O-N 3.43Å; L115-A119 VanDerWaalsContact O-CB 3.31Å; L115-A119 WeakPolarHBondContact O-CB 3.23Å; L115-A119 PolarHBondContact O-N 2.89Å; L115-I132 HydrophobicContact CD1-CB 4.1Å; L115-I132 HydrophobicContact CD1-CG1 4.29Å; L115-I132 HydrophobicContact CD1-CG2 3.68Å; L115-L135 HydrophobicContact CB-CB 4.33Å; L115-L135 HydrophobicContact CB-CD1 4.3Å; L115-L135 HydrophobicContact CD1-CB 4Å; L115-I139 HydrophobicContact CB-CD1 4.06Å; L115-I139 HydrophobicContact CD2-CD1 3.8Å; L115-F190 HydrophobicContact CD2-CD2 3.92Å; L115-F190 HydrophobicContact CD2-CE2 3.63Å; L115-V193 HydrophobicContact CD2-CG1 3.98Å; L115-V193 HydrophobicContact CG-CG1 3.82Å
116	T	83.3	Confident	79.6	Confident	27 Å²	27	75.2 Å²	75.2	17%	0.166	37%	0.37	C	S	.	.	H	α-helix	trans	-59.3	-44.3	177.3	-57.5	0	0	0	0	111.2	L112 E113 K114 K120 V193	L112-T116 WeakPolarHBondContact O-CB 3.25Å; L112-T116 PolarHBondContact O-N 3.11Å; L112-T116 PolarHBondContact O-OG1 3.27Å; E113-T116 VanDerWaalsContact O-CB 3.31Å; E113-T116 WeakPolarHBondContact O-CB 3.49Å; E113-T116 PolarHBondContact O-N 2.93Å; E113-T116 VanDerWaalsContact O-N 3.15Å; K114-T116 VanDerWaalsContact C-N 3.31Å; K114-T116 PolarHBondContact O-N 2.88Å; T116-K120 HydrophobicContact CG2-CD 3.97Å; T116-K120 WeakPolarHBondContact O-CB 3.16Å; T116-K120 VanDerWaalsContact O-CG 3.3Å; T116-K120 WeakPolarHBondContact O-CG 3.31Å; T116-K120 PolarHBondContact O-N 3.49Å; T116-V193 HydrophobicContact CG2-CG2 3.98Å; T116-V193 WeakPolarHBondContact OG1-CG2 3.32Å
117	I	84	Confident	78.6	Confident	103 Å²	103	73.3 Å²	73.3	53%	0.528	35%	0.354	S	S	.	.	H	α-helix	trans	-62.6	-44.5	177.2	-66.2	164.7	0	0	0	110.4	E113 K114 L115 R121	E113-I117 HydrophobicContact CG-CD1 4.42Å; E113-I117 WeakPolarHBondContact O-CG1 3.3Å; E113-I117 PolarHBondContact O-N 3.38Å; K114-I117 PolarHBondContact O-N 3.44Å; L115-I117 VanDerWaalsContact C-N 3.32Å; L115-I117 PolarHBondContact O-N 2.7Å; I117-R121 PolarHBondContact O-N 3.28Å
118	L	83.7	Confident	78	Confident	24 Å²	24	74.1 Å²	74.1	13%	0.126	35%	0.354	C	S	.	.	H	α-helix	trans	-66.8	-44.3	178.9	-68	173.9	0	0	0	112.4	K114 L115 K120 R121 K128 E131 I132 L135	K114-L118 WeakPolarHBondContact O-CG 3.45Å; K114-L118 PolarHBondContact O-N 2.89Å; K114-L118 VanDerWaalsContact O-N 3.08Å; L115-L118 PolarHBondContact O-N 3.43Å; L118-K120 VanDerWaalsContact C-N 3.29Å; L118-K120 PolarHBondContact O-N 3.26Å; L118-R121 PolarHBondContact O-N 2.86Å; L118-K128 HydrophobicContact CD2-CD 4.08Å; L118-E131 HydrophobicContact CD1-CB 4.44Å; L118-E131 HydrophobicContact CD1-CG 3.85Å; L118-I132 HydrophobicContact CB-CD1 4.2Å; L118-I132 HydrophobicContact CB-CG1 3.82Å; L118-I132 HydrophobicContact CD1-CG1 4.3Å; L118-L135 HydrophobicContact CD1-CD1 3.77Å
119	A	80.6	Confident	77.3	Confident	4 Å²	4	75.4 Å²	75.4	3%	0.033	37%	0.365	C	S	.	.	H	α-helix	trans	-67.2	-29	179.7	0	0	0	0	0	113	L115 V193 R197 N200	L115-A119 VanDerWaalsContact O-CB 3.31Å; L115-A119 WeakPolarHBondContact O-CB 3.23Å; L115-A119 PolarHBondContact O-N 2.89Å; A119-V193 HydrophobicContact CB-CG1 3.65Å; A119-R197 HydrophobicContact CB-CB 4.46Å; A119-N200 PolarHBondContact O-ND2 2.91Å
120	K	76.1	Confident	77.1	Confident	138 Å²	138	77 Å²	77	60%	0.6	38%	0.38	S	S	*	.	H	α-helix	trans	-83.1	-17.7	176.4	-73.1	179.4	178.4	176.9	0	113.6	T116 L118 K122	T116-K120 HydrophobicContact CG2-CD 3.97Å; T116-K120 WeakPolarHBondContact O-CB 3.16Å; T116-K120 VanDerWaalsContact O-CG 3.3Å; T116-K120 WeakPolarHBondContact O-CG 3.31Å; T116-K120 PolarHBondContact O-N 3.49Å; L118-K120 VanDerWaalsContact C-N 3.29Å; L118-K120 PolarHBondContact O-N 3.26Å; K120-K122 PolarHBondContact O-N 2.67Å; K120-K122 VanDerWaalsContact O-N 3.08Å
121	R	71.3	Confident	77.2	Confident	131 Å²	131	76.6 Å²	76.6	49%	0.494	37%	0.368	S	S	.	.			trans	-66.7	107.9	175	-96.4	178.1	72.4	94.5	-8.9	109.7	I117 L118 S123 D126	I117-R121 PolarHBondContact O-N 3.28Å; L118-R121 PolarHBondContact O-N 2.86Å; R121-S123 PolarHBondContact O-N 3Å; R121-D126 IonicContact CZ-OD2 3.35Å; R121-D126 IonicContact NE-OD2 2.63Å; R121-D126 IonicContact NH2-OD2 2.79Å; R121-D126 PolarHBondContact NH2-OD2 3.05Å
122	K	63.6	Low	77.1	Confident	174 Å²	174	73.8 Å²	73.8	76%	0.757	36%	0.356	S	S	*	.			trans	-81.8	43.5	176.1	-60.7	-172.8	179.8	-175	0	112.9	K120	K120-K122 PolarHBondContact O-N 2.67Å; K120-K122 VanDerWaalsContact O-N 3.08Å
123	S	60.8	Low	77	Confident	37 Å²	37	77.7 Å²	77.7	26%	0.259	37%	0.374	S	S	.	.			trans	-91.8	125	177.8	-170.9	0	0	0	0	110.5	R121 D126	R121-S123 PolarHBondContact O-N 3Å; S123-D126 PolarHBondContact OG-N 3.2Å
124	L	56.9	Low	77.4	Confident	98 Å²	98	77 Å²	77	51%	0.513	37%	0.371	S	S	.	.	S	Bend	trans	-77.9	-20.7	178.1	-67.7	170	0	0	0	113.2	Q204	L124-Q204 HydrophobicContact CD2-CG 3.75Å
125	F	55.6	Low	77.8	Confident	201 Å²	201	73.1 Å²	73.1	88%	0.882	36%	0.355	S	S	*	.	S	Bend	trans	-112.5	-5.6	-171.4	-61.8	-77.7	0	0	0	113.5
126	D	62.2	Low	77.9	Confident	69 Å²	69	73.7 Å²	73.7	37%	0.369	36%	0.358	S	S	.	.			trans	-137.8	47.9	179.1	-176.6	37.2	0	0	0	109.1	R121 S123 K128	R121-D126 IonicContact CZ-OD2 3.35Å; R121-D126 IonicContact NE-OD2 2.63Å; R121-D126 IonicContact NH2-OD2 2.79Å; R121-D126 PolarHBondContact NH2-OD2 3.05Å; S123-D126 PolarHBondContact OG-N 3.2Å; D126-K128 PolarHBondContact O-N 3.32Å
127	D	70.1	Confident	78.4	Confident	38 Å²	38	79.8 Å²	79.8	20%	0.203	38%	0.379	C	S	.	.			trans	-78.7	101.6	170.1	-173.2	1.7	0	0	0	107.5	A129 R197 R269	D127-A129 PolarHBondContact O-N 3.14Å; D127-R197 VanDerWaalsContact CG-NH2 3.27Å; D127-R197 IonicContact OD1-CZ 3.69Å; D127-R197 IonicContact OD1-NH1 3.48Å; D127-R197 IonicContact OD1-NH2 2.77Å; D127-R197 PolarHBondContact OD1-NH2 3.33Å; D127-R197 IonicContact OD2-CZ 4Å; D127-R197 IonicContact OD2-NH1 3.42Å; D127-R197 PolarHBondContact OD2-NH1 3.32Å; D127-R197 IonicContact OD2-NH2 2.63Å; D127-R197 PolarHBondContact OD2-NH2 3.04Å; D127-R269 IonicContact OD2-CZ 2.97Å; D127-R269 VanDerWaalsContact OD2-CZ 3.25Å; D127-R269 IonicContact OD2-NH1 3.87Å; D127-R269 PolarHBondContact OD2-NH1 2.96Å; D127-R269 IonicContact OD2-NH2 2.7Å; D127-R269 PolarHBondContact OD2-NH2 3.5Å
128	K	80.6	Confident	78.9	Confident	93 Å²	93	77.9 Å²	77.9	40%	0.404	37%	0.369	S	S	.	.			trans	-73.9	60.5	176.5	-56.9	-163.8	177.5	-137.8	0	110.6	L118 D126 V130 E131 I132	L118-K128 HydrophobicContact CD2-CD 4.08Å; D126-K128 PolarHBondContact O-N 3.32Å; K128-V130 VanDerWaalsContact C-N 3.32Å; K128-V130 PolarHBondContact O-N 3.45Å; K128-E131 HydrophobicContact CB-CB 4.06Å; K128-E131 WeakPolarHBondContact CD-OE2 3.48Å; K128-E131 PolarHBondContact O-N 3.17Å; K128-I132 WeakPolarHBondContact O-CG1 3.45Å; K128-I132 PolarHBondContact O-N 3.3Å
129	A	81.1	Confident	79.4	Confident	29 Å²	29	76.7 Å²	76.7	24%	0.24	36%	0.363	C	S	.	.	H	α-helix	trans	-58.4	-43.2	-171.4	0	0	0	0	0	112.1	D127 I132 E133	D127-A129 PolarHBondContact O-N 3.14Å; A129-I132 PolarHBondContact O-N 2.9Å; A129-E133 WeakPolarHBondContact O-CB 3.42Å; A129-E133 PolarHBondContact O-N 3.45Å
130	V	85.3	Confident	80	Confident	98 Å²	98	78.7 Å²	78.7	59%	0.594	37%	0.371	S	S	*	.	H	α-helix	trans	-61.2	-47.4	177.1	-177.4	0	0	0	0	111.3	K128 I132 E133 E134	K128-V130 VanDerWaalsContact C-N 3.32Å; K128-V130 PolarHBondContact O-N 3.45Å; V130-I132 VanDerWaalsContact C-N 3.32Å; V130-I132 PolarHBondContact O-N 3.26Å; V130-E133 PolarHBondContact O-N 3.45Å; V130-E134 HydrophobicContact CG1-CG 4.41Å; V130-E134 WeakPolarHBondContact O-CB 3.4Å; V130-E134 WeakPolarHBondContact O-CG 3.17Å; V130-E134 PolarHBondContact O-N 3.32Å
131	E	88.8	Confident	80.9	Confident	48 Å²	48	77.5 Å²	77.5	22%	0.224	37%	0.368	C	S	.	.	H	α-helix	trans	-65.1	-36.2	179.7	-171.6	174.7	-168.2	0	0	111.9	K114 L118 K128 L135	K114-E131 WeakPolarHBondContact CE-OE1 3.47Å; K114-E131 IonicContact NZ-OE1 2.82Å; K114-E131 PolarHBondContact NZ-OE1 3.2Å; L118-E131 HydrophobicContact CD1-CB 4.44Å; L118-E131 HydrophobicContact CD1-CG 3.85Å; K128-E131 HydrophobicContact CB-CB 4.06Å; K128-E131 WeakPolarHBondContact CD-OE2 3.48Å; K128-E131 PolarHBondContact O-N 3.17Å; E131-L135 HydrophobicContact CG-CD1 4.19Å; E131-L135 VanDerWaalsContact O-CB 3.28Å; E131-L135 WeakPolarHBondContact O-CB 3.3Å; E131-L135 VanDerWaalsContact O-CG 3.26Å; E131-L135 WeakPolarHBondContact O-CG 3.31Å; E131-L135 PolarHBondContact O-N 2.88Å
132	I	88.1	Confident	82.1	Confident	7 Å²	7	73 Å²	73	4%	0.036	35%	0.354	C	S	.	.	H	α-helix	trans	-65.9	-44.6	174.8	-67	167.1	0	0	0	110.2	L115 L118 K128 A129 V130 L135 T136 R197	L115-I132 HydrophobicContact CD1-CB 4.1Å; L115-I132 HydrophobicContact CD1-CG1 4.29Å; L115-I132 HydrophobicContact CD1-CG2 3.68Å; L118-I132 HydrophobicContact CB-CD1 4.2Å; L118-I132 HydrophobicContact CB-CG1 3.82Å; L118-I132 HydrophobicContact CD1-CG1 4.3Å; K128-I132 WeakPolarHBondContact O-CG1 3.45Å; K128-I132 PolarHBondContact O-N 3.3Å; A129-I132 PolarHBondContact O-N 2.9Å; V130-I132 VanDerWaalsContact C-N 3.32Å; V130-I132 PolarHBondContact O-N 3.26Å; I132-L135 PolarHBondContact O-N 2.87Å; I132-T136 VanDerWaalsContact O-CB 3.23Å; I132-T136 WeakPolarHBondContact O-CB 3.3Å; I132-T136 PolarHBondContact O-N 3.48Å; I132-T136 PolarHBondContact O-OG1 2.92Å; I132-R197 HydrophobicContact CG2-CG 4.38Å
133	E	88.8	Confident	83.6	Confident	86 Å²	86	64.8 Å²	64.8	40%	0.402	32%	0.318	S	S	.	.	H	α-helix	trans	-65.2	-44.9	178.9	-173	166.2	-157	0	0	112	A129 V130 T136 Y137	A129-E133 WeakPolarHBondContact O-CB 3.42Å; A129-E133 PolarHBondContact O-N 3.45Å; V130-E133 PolarHBondContact O-N 3.45Å; E133-T136 WeakPolarHBondContact O-CB 3.35Å; E133-T136 PolarHBondContact O-N 2.96Å; E133-Y137 WeakPolarHBondContact O-CB 3.49Å; E133-Y137 PolarHBondContact O-N 3.33Å
134	E	91.5	Very high	85.1	Confident	114 Å²	114	65.4 Å²	65.4	53%	0.533	32%	0.319	S	S	.	.	H	α-helix	trans	-59.3	-48.7	174.1	-73.9	177.7	175.4	0	0	111.9	V130 T136 Y137 I138	V130-E134 HydrophobicContact CG1-CG 4.41Å; V130-E134 WeakPolarHBondContact O-CB 3.4Å; V130-E134 WeakPolarHBondContact O-CG 3.17Å; V130-E134 PolarHBondContact O-N 3.32Å; E134-T136 VanDerWaalsContact C-N 3.3Å; E134-T136 PolarHBondContact O-N 3.24Å; E134-Y137 PolarHBondContact O-N 3.12Å; E134-I138 VanDerWaalsContact O-CG1 3.25Å; E134-I138 WeakPolarHBondContact O-CG1 3.48Å; E134-I138 PolarHBondContact O-N 2.86Å
135	L	92.7	Very high	87	Confident	16 Å²	16	63.3 Å²	63.3	8%	0.084	31%	0.312	C	S	.	.	H	α-helix	trans	-63.1	-39	177.3	-77.8	171.9	0	0	0	111.6	K111 K114 L115 L118 E131 I132 I138 I139	K111-L135 HydrophobicContact CB-CD2 4.23Å; K114-L135 HydrophobicContact CD-CD1 4.15Å; K114-L135 HydrophobicContact CG-CD1 4.15Å; L115-L135 HydrophobicContact CB-CB 4.33Å; L115-L135 HydrophobicContact CB-CD1 4.3Å; L115-L135 HydrophobicContact CD1-CB 4Å; L118-L135 HydrophobicContact CD1-CD1 3.77Å; E131-L135 HydrophobicContact CG-CD1 4.19Å; E131-L135 VanDerWaalsContact O-CB 3.28Å; E131-L135 WeakPolarHBondContact O-CB 3.3Å; E131-L135 VanDerWaalsContact O-CG 3.26Å; E131-L135 WeakPolarHBondContact O-CG 3.31Å; E131-L135 PolarHBondContact O-N 2.88Å; I132-L135 PolarHBondContact O-N 2.87Å; L135-I138 PolarHBondContact O-N 2.99Å; L135-I139 VanDerWaalsContact O-CB 3.31Å; L135-I139 WeakPolarHBondContact O-CB 3.31Å; L135-I139 VanDerWaalsContact O-CD1 3.32Å; L135-I139 WeakPolarHBondContact O-CD1 3.38Å; L135-I139 WeakPolarHBondContact O-CG1 3.41Å; L135-I139 PolarHBondContact O-N 3.31Å
136	T	91.6	Very high	88.9	Confident	13 Å²	13	53.8 Å²	53.8	8%	0.08	27%	0.27	C	S	.	.	H	α-helix	trans	-61.4	-46	176.4	-63.3	0	0	0	0	110.4	I132 E133 E134 K140 F190 L194	I132-T136 VanDerWaalsContact O-CB 3.23Å; I132-T136 WeakPolarHBondContact O-CB 3.3Å; I132-T136 PolarHBondContact O-N 3.48Å; I132-T136 PolarHBondContact O-OG1 2.92Å; E133-T136 WeakPolarHBondContact O-CB 3.35Å; E133-T136 PolarHBondContact O-N 2.96Å; E134-T136 VanDerWaalsContact C-N 3.3Å; E134-T136 PolarHBondContact O-N 3.24Å; T136-K140 WeakPolarHBondContact O-CB 3.46Å; T136-K140 PolarHBondContact O-N 2.72Å; T136-F190 HydrophobicContact CG2-CE2 4.31Å; T136-F190 HydrophobicContact CG2-CZ 3.96Å; T136-L194 HydrophobicContact CG2-CD2 3.84Å
137	Y	93.3	Very high	90.4	Very high	154 Å²	154	51 Å²	51	60%	0.604	26%	0.255	S	S	*	.	H	α-helix	trans	-64.1	-46.4	177.6	-176	-92.8	0	0	0	112.2	E133 E134 K140 Q141	E133-Y137 WeakPolarHBondContact O-CB 3.49Å; E133-Y137 PolarHBondContact O-N 3.33Å; E134-Y137 PolarHBondContact O-N 3.12Å; Y137-K140 WeakPolarHBondContact O-CB 3.33Å; Y137-K140 PolarHBondContact O-N 3.48Å; Y137-Q141 PolarHBondContact O-N 3.15Å
138	I	94.9	Very high	91.5	Very high	63 Å²	63	56 Å²	56	32%	0.323	28%	0.275	S	S	.	.	H	α-helix	trans	-62.5	-46.6	179.1	-67.6	164.3	0	0	0	110.7	K111 E134 L135 Q141 D142	K111-I138 HydrophobicContact CD-CG2 3.69Å; K111-I138 VanDerWaalsContact NZ-CG2 3.29Å; E134-I138 VanDerWaalsContact O-CG1 3.25Å; E134-I138 WeakPolarHBondContact O-CG1 3.48Å; E134-I138 PolarHBondContact O-N 2.86Å; L135-I138 PolarHBondContact O-N 2.99Å; I138-Q141 PolarHBondContact O-N 2.81Å; I138-D142 WeakPolarHBondContact O-CB 3.46Å; I138-D142 VanDerWaalsContact O-CG 3.3Å; I138-D142 PolarHBondContact O-N 2.95Å
139	I	94.7	Very high	92.1	Very high	0 Å²	0	53.5 Å²	53.5	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-65.4	-41.2	179.6	-68.1	162.2	0	0	0	110.5	T108 K111 L112 L115 L135 Q141 D142 I143 F190	T108-I139 HydrophobicContact CG2-CG1 4.38Å; T108-I139 HydrophobicContact CG2-CG2 4.1Å; K111-I139 HydrophobicContact CB-CD1 4.11Å; K111-I139 HydrophobicContact CB-CG1 3.94Å; L112-I139 HydrophobicContact CB-CD1 4.17Å; L112-I139 HydrophobicContact CD1-CD1 4.41Å; L115-I139 HydrophobicContact CB-CD1 4.06Å; L115-I139 HydrophobicContact CD2-CD1 3.8Å; L135-I139 VanDerWaalsContact O-CB 3.31Å; L135-I139 WeakPolarHBondContact O-CB 3.31Å; L135-I139 VanDerWaalsContact O-CD1 3.32Å; L135-I139 WeakPolarHBondContact O-CD1 3.38Å; L135-I139 WeakPolarHBondContact O-CG1 3.41Å; L135-I139 PolarHBondContact O-N 3.31Å; I139-Q141 VanDerWaalsContact C-N 3.32Å; I139-Q141 PolarHBondContact O-N 3.05Å; I139-D142 PolarHBondContact O-N 3.06Å; I139-I143 HydrophobicContact CG2-CD1 3.67Å; I139-I143 HydrophobicContact CG2-CG1 4.18Å; I139-I143 WeakPolarHBondContact O-CB 3.42Å; I139-I143 WeakPolarHBondContact O-CG1 3.4Å; I139-I143 PolarHBondContact O-N 3.43Å; I139-F190 HydrophobicContact CB-CE2 4.12Å; I139-F190 HydrophobicContact CB-CZ 4.2Å; I139-F190 HydrophobicContact CD1-CE2 4.46Å; I139-F190 HydrophobicContact CG2-CD1 3.98Å; I139-F190 HydrophobicContact CG2-CD2 3.79Å; I139-F190 HydrophobicContact CG2-CE1 4.03Å; I139-F190 HydrophobicContact CG2-CE2 3.83Å; I139-F190 HydrophobicContact CG2-CG 3.87Å; I139-F190 HydrophobicContact CG2-CZ 3.95Å
140	K	93.2	Very high	92.7	Very high	45 Å²	45	52.1 Å²	52.1	20%	0.196	25%	0.254	C	S	.	.	H	α-helix	trans	-55.3	-48	173.4	174.3	-178.2	177.1	162.2	0	111.2	T136 Y137 N144 T279 E282	T136-K140 WeakPolarHBondContact O-CB 3.46Å; T136-K140 PolarHBondContact O-N 2.72Å; Y137-K140 WeakPolarHBondContact O-CB 3.33Å; Y137-K140 PolarHBondContact O-N 3.48Å; K140-N144 PolarHBondContact O-N 3.48Å; K140-N144 PolarHBondContact O-ND2 3.31Å; K140-T279 HydrophobicContact CB-CG2 4.33Å; K140-T279 HydrophobicContact CD-CG2 4.04Å; K140-T279 HydrophobicContact CG-CG2 4.24Å; K140-E282 WeakPolarHBondContact CE-OE2 3.36Å; K140-E282 IonicContact NZ-OE1 2.86Å; K140-E282 PolarHBondContact NZ-OE1 3.06Å; K140-E282 IonicContact NZ-OE2 2.82Å; K140-E282 PolarHBondContact NZ-OE2 3.37Å
141	Q	94.4	Very high	93	Very high	114 Å²	114	48.5 Å²	48.5	53%	0.533	23%	0.234	S	C	.	.	H	α-helix	trans	-65.9	-44.3	178.9	-174.3	177.5	4	0	0	111.9	Y137 I138 I139 N144 S145	Y137-Q141 PolarHBondContact O-N 3.15Å; I138-Q141 PolarHBondContact O-N 2.81Å; I139-Q141 VanDerWaalsContact C-N 3.32Å; I139-Q141 PolarHBondContact O-N 3.05Å; Q141-N144 PolarHBondContact O-N 2.98Å; Q141-S145 WeakPolarHBondContact O-CB 3.42Å; Q141-S145 PolarHBondContact O-N 3.49Å
142	D	95.8	Very high	93.1	Very high	37 Å²	37	52 Å²	52	20%	0.198	25%	0.25	C	C	.	.	H	α-helix	trans	-61.4	-47	179.2	-76.3	-7	0	0	0	111.4	T108 K111 I138 I139 N144 S145 L146	T108-D142 HydrophobicContact CG2-CB 3.66Å; T108-D142 VanDerWaalsContact OG1-CB 3.29Å; T108-D142 WeakPolarHBondContact OG1-CB 3.45Å; T108-D142 PolarHBondContact OG1-OD2 3.4Å; K111-D142 IonicContact NZ-OD1 3.28Å; K111-D142 IonicContact NZ-OD2 2.9Å; K111-D142 PolarHBondContact NZ-OD2 2.83Å; I138-D142 WeakPolarHBondContact O-CB 3.46Å; I138-D142 VanDerWaalsContact O-CG 3.3Å; I138-D142 PolarHBondContact O-N 2.95Å; I139-D142 PolarHBondContact O-N 3.06Å; D142-N144 VanDerWaalsContact C-N 3.34Å; D142-N144 PolarHBondContact O-N 3.49Å; D142-S145 WeakPolarHBondContact O-CB 3.29Å; D142-S145 PolarHBondContact O-N 2.88Å; D142-L146 WeakPolarHBondContact O-CB 3.49Å; D142-L146 VanDerWaalsContact O-CG 3.24Å; D142-L146 WeakPolarHBondContact O-CG 3.2Å; D142-L146 PolarHBondContact O-N 2.84Å
143	I	94.6	Very high	93.2	Very high	0 Å²	0	51.7 Å²	51.7	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-60.7	-43.5	178.1	-71.8	174.4	0	0	0	110.8	T108 I139 L146 N147 L183 M186 F190 L283 I286	T108-I143 HydrophobicContact CG2-CG1 4.42Å; I139-I143 HydrophobicContact CG2-CD1 3.67Å; I139-I143 HydrophobicContact CG2-CG1 4.18Å; I139-I143 WeakPolarHBondContact O-CB 3.42Å; I139-I143 WeakPolarHBondContact O-CG1 3.4Å; I139-I143 PolarHBondContact O-N 3.43Å; I143-L146 PolarHBondContact O-N 2.88Å; I143-N147 WeakPolarHBondContact O-CB 3.47Å; I143-N147 PolarHBondContact O-N 2.95Å; I143-L183 HydrophobicContact CG1-CD1 4.47Å; I143-L183 HydrophobicContact CG2-CD1 4.22Å; I143-M186 HydrophobicContact CD1-CG 4.46Å; I143-M186 HydrophobicContact CD1-SD 4.41Å; I143-M186 HydrophobicContact CG1-SD 4Å; I143-F190 HydrophobicContact CD1-CB 4.23Å; I143-F190 HydrophobicContact CD1-CD1 3.65Å; I143-F190 HydrophobicContact CD1-CE1 4.33Å; I143-F190 HydrophobicContact CD1-CG 4.18Å; I143-L283 HydrophobicContact CD1-CD2 4.24Å; I143-L283 HydrophobicContact CG2-CD2 4.14Å; I143-I286 HydrophobicContact CG2-CD1 3.86Å
144	N	93.9	Very high	93.2	Very high	51 Å²	51	48.2 Å²	48.2	27%	0.273	23%	0.232	S	C	.	.	H	α-helix	trans	-63.2	-42	176.3	-86.8	-73.4	0	0	0	112.1	K140 Q141 D142 K148	K140-N144 PolarHBondContact O-N 3.48Å; K140-N144 PolarHBondContact O-ND2 3.31Å; Q141-N144 PolarHBondContact O-N 2.98Å; D142-N144 VanDerWaalsContact C-N 3.34Å; D142-N144 PolarHBondContact O-N 3.49Å; N144-K148 WeakPolarHBondContact O-CG 3.33Å; N144-K148 PolarHBondContact O-N 3.42Å; N144-K148 VanDerWaalsContact O-N 3.13Å
145	S	95.4	Very high	93.1	Very high	53 Å²	53	47.5 Å²	47.5	37%	0.371	23%	0.232	S	C	.	.	H	α-helix	trans	-63	-47.4	175.4	-176.7	0	0	0	0	111.3	Q141 D142 N147 K148 Q149	Q141-S145 WeakPolarHBondContact O-CB 3.42Å; Q141-S145 PolarHBondContact O-N 3.49Å; D142-S145 WeakPolarHBondContact O-CB 3.29Å; D142-S145 PolarHBondContact O-N 2.88Å; S145-N147 PolarHBondContact O-N 3.33Å; S145-K148 PolarHBondContact O-N 2.94Å; S145-Q149 WeakPolarHBondContact O-CG 3.46Å; S145-Q149 PolarHBondContact O-N 3.33Å; S145-Q149 PolarHBondContact OG-NE2 3.38Å; S145-Q149 VanDerWaalsContact OG-NE2 3.1Å
146	L	95.6	Very high	92.8	Very high	2 Å²	2	50.5 Å²	50.5	1%	0.01	24%	0.244	C	C	.	.	H	α-helix	trans	-59.9	-44.2	177.6	-74	166.9	0	0	0	111.6	I101 D104 L105 D142 I143 K148 Q149 I150 L183	I101-L146 HydrophobicContact CG2-CD2 3.97Å; D104-L146 HydrophobicContact CB-CD2 3.76Å; L105-L146 HydrophobicContact CB-CD1 4.43Å; L105-L146 HydrophobicContact CB-CD2 4.29Å; L105-L146 HydrophobicContact CD1-CD1 4.02Å; D142-L146 WeakPolarHBondContact O-CB 3.49Å; D142-L146 VanDerWaalsContact O-CG 3.24Å; D142-L146 WeakPolarHBondContact O-CG 3.2Å; D142-L146 PolarHBondContact O-N 2.84Å; I143-L146 PolarHBondContact O-N 2.88Å; L146-K148 PolarHBondContact O-N 3.27Å; L146-Q149 PolarHBondContact O-N 2.91Å; L146-I150 WeakPolarHBondContact O-CB 3.38Å; L146-I150 VanDerWaalsContact O-CG1 3.26Å; L146-I150 WeakPolarHBondContact O-CG1 3.2Å; L146-I150 PolarHBondContact O-N 3.33Å; L146-L183 HydrophobicContact CB-CD1 3.9Å; L146-L183 HydrophobicContact CB-CD2 4.3Å; L146-L183 HydrophobicContact CD1-CD1 4.11Å
147	N	93.6	Very high	92.5	Very high	9 Å²	9	50 Å²	50	5%	0.048	24%	0.242	C	C	.	.	H	α-helix	trans	-59.7	-45.5	177	-171.6	39.7	0	0	0	111.5	I143 S145 I150 A151 L183 I286 Q289	I143-N147 WeakPolarHBondContact O-CB 3.47Å; I143-N147 PolarHBondContact O-N 2.95Å; S145-N147 PolarHBondContact O-N 3.33Å; N147-I150 PolarHBondContact O-N 3.3Å; N147-A151 WeakPolarHBondContact O-CB 3.44Å; N147-A151 PolarHBondContact O-N 2.97Å; N147-L183 HydrophobicContact CB-CD2 3.96Å; N147-I286 HydrophobicContact CB-CG2 4.38Å; N147-Q289 PolarHBondContact ND2-OE1 3.5Å
148	K	93.7	Very high	92	Very high	143 Å²	143	48.3 Å²	48.3	62%	0.622	23%	0.234	S	C	*	.	H	α-helix	trans	-62.7	-44.9	175.9	-71.5	175.4	-177.2	179.3	0	112.3	N144 S145 L146 A151 Q152	N144-K148 WeakPolarHBondContact O-CG 3.33Å; N144-K148 PolarHBondContact O-N 3.42Å; N144-K148 VanDerWaalsContact O-N 3.13Å; S145-K148 PolarHBondContact O-N 2.94Å; L146-K148 PolarHBondContact O-N 3.27Å; K148-A151 PolarHBondContact O-N 3.36Å; K148-Q152 WeakPolarHBondContact O-CG 3.09Å; K148-Q152 PolarHBondContact O-N 3.49Å
149	Q	94.3	Very high	91.5	Very high	42 Å²	42	49.4 Å²	49.4	20%	0.196	25%	0.253	C	S	.	.	H	α-helix	trans	-65	-39	179.3	-70.6	-179.2	54.9	0	0	112	I101 S145 L146 Q152 L153	I101-Q149 HydrophobicContact CD1-CB 3.89Å; I101-Q149 HydrophobicContact CG1-CB 3.81Å; S145-Q149 WeakPolarHBondContact O-CG 3.46Å; S145-Q149 PolarHBondContact O-N 3.33Å; S145-Q149 PolarHBondContact OG-NE2 3.38Å; S145-Q149 VanDerWaalsContact OG-NE2 3.1Å; L146-Q149 PolarHBondContact O-N 2.91Å; Q149-Q152 PolarHBondContact O-N 3.32Å; Q149-L153 WeakPolarHBondContact O-CB 3.45Å; Q149-L153 PolarHBondContact O-N 3.46Å
150	I	92.7	Very high	90.6	Very high	0 Å²	0	52 Å²	52	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-67.6	-40.4	176.5	-72.3	172.8	0	0	0	111.1	I101 L146 N147 L153 Q154 L179 Q180 L183 M293	I101-I150 HydrophobicContact CD1-CG1 4.38Å; I101-I150 HydrophobicContact CG2-CD1 4.1Å; I101-I150 HydrophobicContact CG2-CG1 3.76Å; L146-I150 WeakPolarHBondContact O-CB 3.38Å; L146-I150 VanDerWaalsContact O-CG1 3.26Å; L146-I150 WeakPolarHBondContact O-CG1 3.2Å; L146-I150 PolarHBondContact O-N 3.33Å; N147-I150 PolarHBondContact O-N 3.3Å; I150-L153 WeakPolarHBondContact O-CB 3.38Å; I150-L153 PolarHBondContact O-N 2.98Å; I150-Q154 PolarHBondContact O-N 2.91Å; I150-L179 HydrophobicContact CD1-CB 4.01Å; I150-L179 HydrophobicContact CG1-CB 4.37Å; I150-Q180 HydrophobicContact CG2-CG 3.43Å; I150-Q180 VanDerWaalsContact CG2-CG 3.43Å; I150-L183 HydrophobicContact CD1-CB 4.13Å; I150-L183 HydrophobicContact CD1-CD2 3.8Å; I150-M293 HydrophobicContact CG2-SD 4.26Å
151	A	90.9	Very high	89.4	Confident	21 Å²	21	51.3 Å²	51.3	17%	0.174	27%	0.27	C	S	.	.	H	α-helix	trans	-60.8	-46.4	174.1	0	0	0	0	0	111.5	N147 K148 L153 Q154 D155 M293	N147-A151 WeakPolarHBondContact O-CB 3.44Å; N147-A151 PolarHBondContact O-N 2.97Å; K148-A151 PolarHBondContact O-N 3.36Å; A151-L153 VanDerWaalsContact C-N 3.3Å; A151-L153 PolarHBondContact O-N 3.03Å; A151-Q154 WeakPolarHBondContact O-CB 3.4Å; A151-Q154 PolarHBondContact O-N 2.9Å; A151-Q154 VanDerWaalsContact O-N 3.15Å; A151-D155 PolarHBondContact O-N 2.89Å; A151-M293 HydrophobicContact CB-CE 4.43Å
152	Q	92.1	Very high	88	Confident	121 Å²	121	50.9 Å²	50.9	57%	0.565	28%	0.28	S	S	*	.	H	α-helix	trans	-60.1	-40.3	174.5	-71.2	173.7	-1.2	0	0	112.4	K148 Q149 Q154 D155 F156	K148-Q152 WeakPolarHBondContact O-CG 3.09Å; K148-Q152 PolarHBondContact O-N 3.49Å; Q149-Q152 PolarHBondContact O-N 3.32Å; Q152-Q154 VanDerWaalsContact C-N 3.32Å; Q152-D155 PolarHBondContact O-N 3.18Å; Q152-F156 WeakPolarHBondContact O-CB 3.34Å; Q152-F156 PolarHBondContact O-N 3.47Å
153	L	90.1	Very high	86.5	Confident	1 Å²	1	57.4 Å²	57.4	1%	0.005	31%	0.309	C	S	.	.	H	α-helix	trans	-63.9	-39.8	176.8	-170.2	68.3	0	0	0	111.2	F94 M97 A98 I101 Q149 I150 A151 F156 V157 V176 L179	F94-L153 HydrophobicContact CD2-CD1 3.32Å; F94-L153 HydrophobicContact CD2-CG 4.02Å; F94-L153 HydrophobicContact CE2-CD1 3.41Å; F94-L153 VanDerWaalsContact CE2-CD1 3.41Å; F94-L153 HydrophobicContact CE2-CD2 3.92Å; F94-L153 HydrophobicContact CE2-CG 3.57Å; F94-L153 HydrophobicContact CG-CD1 4.25Å; F94-L153 HydrophobicContact CZ-CD1 4.38Å; F94-L153 HydrophobicContact CZ-CD2 4.31Å; F94-L153 HydrophobicContact CZ-CG 4.43Å; M97-L153 HydrophobicContact CB-CD1 3.97Å; A98-L153 HydrophobicContact CB-CD2 4.17Å; I101-L153 HydrophobicContact CD1-CB 4.25Å; I101-L153 HydrophobicContact CD1-CD2 3.93Å; Q149-L153 WeakPolarHBondContact O-CB 3.45Å; Q149-L153 PolarHBondContact O-N 3.46Å; I150-L153 WeakPolarHBondContact O-CB 3.38Å; I150-L153 PolarHBondContact O-N 2.98Å; A151-L153 VanDerWaalsContact C-N 3.3Å; A151-L153 PolarHBondContact O-N 3.03Å; L153-F156 WeakPolarHBondContact O-CB 3.49Å; L153-F156 PolarHBondContact O-N 2.9Å; L153-V157 WeakPolarHBondContact O-CG2 3.49Å; L153-V157 PolarHBondContact O-N 3.25Å; L153-V157 VanDerWaalsContact O-N 3.11Å; L153-V176 HydrophobicContact CD2-CG2 3.8Å; L153-V176 HydrophobicContact CG-CG2 3.88Å; L153-L179 HydrophobicContact CD2-CD1 4Å
154	Q	88.9	Confident	85.1	Confident	14 Å²	14	58.7 Å²	58.7	7%	0.065	32%	0.318	C	S	.	.	H	α-helix	trans	-65.5	-45.2	175.5	-174.3	179.8	2.2	0	0	111.7	I150 A151 Q152 F156 V157 R158 V176 M293	I150-Q154 PolarHBondContact O-N 2.91Å; A151-Q154 WeakPolarHBondContact O-CB 3.4Å; A151-Q154 PolarHBondContact O-N 2.9Å; A151-Q154 VanDerWaalsContact O-N 3.15Å; Q152-Q154 VanDerWaalsContact C-N 3.32Å; Q154-F156 VanDerWaalsContact C-N 3.28Å; Q154-F156 PolarHBondContact O-N 3.13Å; Q154-V157 PolarHBondContact O-N 3.04Å; Q154-V157 VanDerWaalsContact O-N 3.12Å; Q154-R158 WeakPolarHBondContact O-CG 3.35Å; Q154-R158 PolarHBondContact O-N 2.87Å; Q154-V176 HydrophobicContact CB-CG1 4.03Å; Q154-V176 HydrophobicContact CG-CG1 4.28Å; Q154-M293 PolarHBondContact OE1-SD 2.77Å; Q154-M293 VanDerWaalsContact OE1-SD 3.35Å
155	D	88.3	Confident	83.9	Confident	99 Å²	99	58.8 Å²	58.8	53%	0.529	33%	0.331	S	S	.	.	H	α-helix	trans	-60.5	-40	176.4	-69.7	-25.3	0	0	0	111.4	A151 Q152 V157 R158 A159	A151-D155 PolarHBondContact O-N 2.89Å; Q152-D155 PolarHBondContact O-N 3.18Å; D155-V157 VanDerWaalsContact C-N 3.32Å; D155-V157 PolarHBondContact O-N 3.25Å; D155-R158 PolarHBondContact O-N 2.82Å; D155-A159 VanDerWaalsContact O-CB 3.29Å; D155-A159 WeakPolarHBondContact O-CB 3.19Å; D155-A159 PolarHBondContact O-N 2.92Å
156	F	86.4	Confident	82.8	Confident	78 Å²	78	66.9 Å²	66.9	34%	0.342	35%	0.353	S	S	.	.	H	α-helix	trans	-59.7	-42.4	174.3	-174.7	-90.3	0	0	0	112	F94 Q152 L153 Q154 K160	F94-F156 HydrophobicContact CB-CD1 4.35Å; F94-F156 HydrophobicContact CB-CE1 3.95Å; F94-F156 HydrophobicContact CD2-CD1 4.2Å; Q152-F156 WeakPolarHBondContact O-CB 3.34Å; Q152-F156 PolarHBondContact O-N 3.47Å; L153-F156 WeakPolarHBondContact O-CB 3.49Å; L153-F156 PolarHBondContact O-N 2.9Å; Q154-F156 VanDerWaalsContact C-N 3.28Å; Q154-F156 PolarHBondContact O-N 3.13Å; F156-K160 HydrophobicContact CE1-CD 4.05Å; F156-K160 HydrophobicContact CZ-CD 4.28Å; F156-K160 VanDerWaalsContact O-CB 3.27Å; F156-K160 WeakPolarHBondContact O-CB 3.3Å; F156-K160 PolarHBondContact O-N 3.49Å
157	V	85.4	Confident	81.6	Confident	3 Å²	3	74 Å²	74	2%	0.018	39%	0.386	C	S	.	.	H	α-helix	trans	-69.7	-39.4	177.5	176.5	0	0	0	0	111.4	F94 L153 Q154 D155 K160 G161 Q169 N173 V176	F94-V157 HydrophobicContact CD2-CG2 3.75Å; F94-V157 HydrophobicContact CE2-CG2 3.33Å; F94-V157 HydrophobicContact CZ-CG2 4.25Å; L153-V157 WeakPolarHBondContact O-CG2 3.49Å; L153-V157 PolarHBondContact O-N 3.25Å; L153-V157 VanDerWaalsContact O-N 3.11Å; Q154-V157 PolarHBondContact O-N 3.04Å; Q154-V157 VanDerWaalsContact O-N 3.12Å; D155-V157 VanDerWaalsContact C-N 3.32Å; D155-V157 PolarHBondContact O-N 3.25Å; V157-K160 PolarHBondContact O-N 3.31Å; V157-G161 PolarHBondContact O-N 2.97Å; V157-G161 VanDerWaalsContact O-N 3.1Å; V157-Q169 VanDerWaalsContact CG1-NE2 3.25Å; V157-Q169 PolarHBondContact O-NE2 3.33Å; V157-N173 WeakPolarHBondContact CG1-OD1 3.38Å; V157-V176 HydrophobicContact CG2-CG2 4.24Å
158	R	83.8	Confident	80.6	Confident	119 Å²	119	75.9 Å²	75.9	45%	0.449	40%	0.396	S	S	.	.	H	α-helix	trans	-64.8	-47.8	175.5	-71.2	-174.9	-171.9	-103.9	7.5	112	Q154 D155 K160 G161 E296	Q154-R158 WeakPolarHBondContact O-CG 3.35Å; Q154-R158 PolarHBondContact O-N 2.87Å; D155-R158 PolarHBondContact O-N 2.82Å; R158-K160 PolarHBondContact O-N 3.43Å; R158-G161 PolarHBondContact O-N 3.22Å; R158-E296 IonicContact CZ-OE1 3.01Å; R158-E296 VanDerWaalsContact CZ-OE1 3.28Å; R158-E296 IonicContact CZ-OE2 2.81Å; R158-E296 IonicContact NH1-OE1 2.82Å; R158-E296 PolarHBondContact NH1-OE1 3.47Å; R158-E296 IonicContact NH2-OE1 3.25Å; R158-E296 PolarHBondContact NH2-OE1 2.98Å; R158-E296 IonicContact NH2-OE2 3.61Å; R158-E296 PolarHBondContact NH2-OE2 3.25Å
159	A	83.4	Confident	79.9	Confident	86 Å²	86	70.7 Å²	70.7	71%	0.711	37%	0.374	S	S	*	.	H	α-helix	trans	-60.5	-32.8	179.2	0	0	0	0	0	112.4	D155	D155-A159 VanDerWaalsContact O-CB 3.29Å; D155-A159 WeakPolarHBondContact O-CB 3.19Å; D155-A159 PolarHBondContact O-N 2.92Å
160	K	75.8	Confident	79.2	Confident	53 Å²	53	71 Å²	71	23%	0.23	38%	0.379	C	S	.	.	H	α-helix	trans	-91.2	-9.4	-177.7	-158.5	166.8	-175.5	175.3	0	114.5	F156 V157 R158 S162 Q163 S164	F156-K160 HydrophobicContact CE1-CD 4.05Å; F156-K160 HydrophobicContact CZ-CD 4.28Å; F156-K160 VanDerWaalsContact O-CB 3.27Å; F156-K160 WeakPolarHBondContact O-CB 3.3Å; F156-K160 PolarHBondContact O-N 3.49Å; V157-K160 PolarHBondContact O-N 3.31Å; R158-K160 PolarHBondContact O-N 3.43Å; K160-S162 PolarHBondContact O-N 3.4Å; K160-S162 VanDerWaalsContact O-N 3.09Å; K160-Q163 PolarHBondContact O-N 3.07Å; K160-Q163 VanDerWaalsContact O-N 3.17Å; K160-S164 WeakPolarHBondContact O-CB 3.46Å; K160-S164 PolarHBondContact O-N 2.92Å
161	G	67.4	Low	78.6	Confident	32 Å²	32	75.5 Å²	75.5	33%	0.33	40%	0.4	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.6	-18.4	-176.7	0	0	0	0	0	115.3	V157 R158	V157-G161 PolarHBondContact O-N 2.97Å; V157-G161 VanDerWaalsContact O-N 3.1Å; R158-G161 PolarHBondContact O-N 3.22Å
162	S	65.6	Low	78.3	Confident	105 Å²	105	75 Å²	75	73%	0.734	40%	0.395	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.1	-22.8	178.2	177.6	0	0	0	0	114.1	K160	K160-S162 PolarHBondContact O-N 3.4Å; K160-S162 VanDerWaalsContact O-N 3.09Å
163	Q	65.6	Low	77.9	Confident	173 Å²	173	70.9 Å²	70.9	81%	0.808	38%	0.377	S	S	*	.	T	Hydrogen-bonded Turn	trans	-117.6	0.7	-169.6	-63.3	-65.6	-51.6	0	0	113.5	K160	K160-Q163 PolarHBondContact O-N 3.07Å; K160-Q163 VanDerWaalsContact O-N 3.17Å
164	S	63.9	Low	77.6	Confident	28 Å²	28	72.8 Å²	72.8	20%	0.196	39%	0.388	C	S	.	.	S	Bend	trans	-115.6	139.3	-169	-156.3	0	0	0	0	111	K160 L168	K160-S164 WeakPolarHBondContact O-CB 3.46Å; K160-S164 PolarHBondContact O-N 2.92Å; S164-L168 VanDerWaalsContact OG-CD2 3.29Å; S164-L168 WeakPolarHBondContact OG-CD2 3.44Å
165	G	69.2	Low	77.5	Confident	53 Å²	53	74.2 Å²	74.2	55%	0.546	40%	0.396	S	S	.	.			trans	-59	143.6	-179.5	0	0	0	0	0	112.7	H167 L168 Q169	G165-H167 VanDerWaalsContact C-N 3.29Å; G165-H167 PolarHBondContact O-N 3.48Å; G165-H167 VanDerWaalsContact O-N 3.11Å; G165-L168 PolarHBondContact O-N 3.39Å; G165-Q169 PolarHBondContact O-N 3.44Å
166	R	71.7	Confident	77.6	Confident	222 Å²	222	69.5 Å²	69.5	84%	0.838	37%	0.371	S	S	*	.	H	α-helix	trans	-43.9	-49.2	-174.4	-73.3	175.8	71.3	107.1	-5.2	113.4	L168 Q169 T170	R166-L168 PolarHBondContact O-N 2.96Å; R166-Q169 PolarHBondContact O-N 3.39Å; R166-T170 PolarHBondContact O-N 2.94Å; R166-T170 PolarHBondContact O-OG1 3.24Å; R166-T170 VanDerWaalsContact O-OG1 3.09Å
167	H	70.4	Confident	77.5	Confident	152 Å²	152	66 Å²	66	70%	0.704	36%	0.356	S	S	*	.	H	α-helix	trans	-62.2	-38.3	-178.8	-179.1	-92	0	0	0	113.7	G165 T170 H171	G165-H167 VanDerWaalsContact C-N 3.29Å; G165-H167 PolarHBondContact O-N 3.48Å; G165-H167 VanDerWaalsContact O-N 3.11Å; H167-T170 PolarHBondContact O-N 3.13Å; H167-H171 PolarHBondContact O-N 3.1Å
168	L	73.7	Confident	77.6	Confident	48 Å²	48	68.6 Å²	68.6	25%	0.251	37%	0.374	S	S	.	.	H	α-helix	trans	-70.2	-37.1	179.9	-178.2	57	0	0	0	111.4	R91 S164 G165 R166 S172	R91-L168 HydrophobicContact CG-CD1 4.31Å; S164-L168 VanDerWaalsContact OG-CD2 3.29Å; S164-L168 WeakPolarHBondContact OG-CD2 3.44Å; G165-L168 PolarHBondContact O-N 3.39Å; R166-L168 PolarHBondContact O-N 2.96Å; L168-S172 WeakPolarHBondContact O-CB 3.44Å; L168-S172 PolarHBondContact O-N 3.2Å; L168-S172 VanDerWaalsContact O-N 3.1Å; L168-S172 PolarHBondContact O-OG 3.18Å
169	Q	78.6	Confident	77.9	Confident	35 Å²	35	63.5 Å²	63.5	16%	0.164	36%	0.356	C	S	.	.	H	α-helix	trans	-65	-46.5	175	-170.1	67.1	7.3	0	0	111	V157 G165 R166 H171 S172 N173	V157-Q169 VanDerWaalsContact CG1-NE2 3.25Å; V157-Q169 PolarHBondContact O-NE2 3.33Å; G165-Q169 PolarHBondContact O-N 3.44Å; R166-Q169 PolarHBondContact O-N 3.39Å; Q169-H171 PolarHBondContact O-N 2.8Å; Q169-S172 PolarHBondContact O-N 3.36Å; Q169-N173 WeakPolarHBondContact O-CB 3.46Å; Q169-N173 PolarHBondContact O-N 3.01Å; Q169-N173 PolarHBondContact O-ND2 3.44Å
170	T	78.4	Confident	78.2	Confident	48 Å²	48	59.4 Å²	59.4	29%	0.294	32%	0.322	S	S	.	.	H	α-helix	trans	-57	-50.3	176.8	-57.6	0	0	0	0	111.4	R166 H167 S172 N173 T174	R166-T170 PolarHBondContact O-N 2.94Å; R166-T170 PolarHBondContact O-OG1 3.24Å; R166-T170 VanDerWaalsContact O-OG1 3.09Å; H167-T170 PolarHBondContact O-N 3.13Å; T170-S172 VanDerWaalsContact C-N 3.33Å; T170-S172 PolarHBondContact O-N 3.43Å; T170-N173 PolarHBondContact O-N 2.89Å; T170-T174 PolarHBondContact O-N 3.1Å; T170-T174 PolarHBondContact O-OG1 3.38Å
171	H	80.5	Confident	78.8	Confident	94 Å²	94	60.3 Å²	60.3	44%	0.435	34%	0.335	S	S	.	.	H	α-helix	trans	-59.1	-43	179	178.3	63.6	0	0	0	113	H167 Q169 T174 I175	H167-H171 PolarHBondContact O-N 3.1Å; Q169-H171 PolarHBondContact O-N 2.8Å; H171-T174 PolarHBondContact O-N 2.91Å; H171-I175 VanDerWaalsContact CE1-CD1 3.5Å; H171-I175 WeakPolarHBondContact CE1-CD1 3.5Å; H171-I175 WeakPolarHBondContact NE2-CD1 2.85Å; H171-I175 WeakPolarHBondContact O-CG1 3.18Å; H171-I175 PolarHBondContact O-N 2.95Å
172	S	85.1	Confident	79.8	Confident	11 Å²	11	63.8 Å²	63.8	8%	0.077	34%	0.341	C	S	.	.	H	α-helix	trans	-65.8	-42.2	180	-52	0	0	0	0	111.4	F94 L168 Q169 T170 I175 V176	F94-S172 WeakPolarHBondContact CZ-O 3.5Å; L168-S172 WeakPolarHBondContact O-CB 3.44Å; L168-S172 PolarHBondContact O-N 3.2Å; L168-S172 VanDerWaalsContact O-N 3.1Å; L168-S172 PolarHBondContact O-OG 3.18Å; Q169-S172 PolarHBondContact O-N 3.36Å; T170-S172 VanDerWaalsContact C-N 3.33Å; T170-S172 PolarHBondContact O-N 3.43Å; S172-I175 PolarHBondContact O-N 2.79Å; S172-V176 WeakPolarHBondContact O-CG2 3.38Å; S172-V176 PolarHBondContact O-N 3.42Å; S172-V176 VanDerWaalsContact O-N 3.07Å
173	N	84.3	Confident	81	Confident	34 Å²	34	58.8 Å²	58.8	18%	0.182	31%	0.306	C	S	.	.	H	α-helix	trans	-60.1	-47.3	172.3	-75.1	-24.7	0	0	0	111.4	V157 Q169 T170 I175 V176 V177	V157-N173 WeakPolarHBondContact CG1-OD1 3.38Å; Q169-N173 WeakPolarHBondContact O-CB 3.46Å; Q169-N173 PolarHBondContact O-N 3.01Å; Q169-N173 PolarHBondContact O-ND2 3.44Å; T170-N173 PolarHBondContact O-N 2.89Å; N173-I175 VanDerWaalsContact C-N 3.3Å; N173-I175 PolarHBondContact O-N 2.95Å; N173-V176 WeakPolarHBondContact O-CB 3.24Å; N173-V176 PolarHBondContact O-N 3.4Å; N173-V176 VanDerWaalsContact O-N 3.12Å; N173-V177 WeakPolarHBondContact O-CG2 3.19Å; N173-V177 PolarHBondContact O-N 2.86Å
174	T	83	Confident	82.1	Confident	41 Å²	41	51.6 Å²	51.6	25%	0.252	28%	0.276	S	S	.	.	H	α-helix	trans	-58.1	-41.6	178.6	-55.4	0	0	0	0	112.2	T170 H171 S178	T170-T174 PolarHBondContact O-N 3.1Å; T170-T174 PolarHBondContact O-OG1 3.38Å; H171-T174 PolarHBondContact O-N 2.91Å; T174-S178 WeakPolarHBondContact O-CB 3.36Å; T174-S178 PolarHBondContact O-N 2.86Å
175	I	87.3	Confident	83.2	Confident	44 Å²	44	53 Å²	53	23%	0.226	29%	0.286	C	S	.	.	H	α-helix	trans	-62.9	-46.9	176	-72.4	171.6	0	0	0	110.8	F94 A98 H171 S172 N173 V177 S178 L179	F94-I175 HydrophobicContact CE1-CB 4.38Å; F94-I175 HydrophobicContact CE1-CD1 3.92Å; F94-I175 HydrophobicContact CE1-CG2 4.35Å; F94-I175 HydrophobicContact CZ-CB 4.14Å; F94-I175 HydrophobicContact CZ-CG2 4.09Å; A98-I175 HydrophobicContact CB-CG2 3.93Å; H171-I175 VanDerWaalsContact CE1-CD1 3.5Å; H171-I175 WeakPolarHBondContact CE1-CD1 3.5Å; H171-I175 WeakPolarHBondContact NE2-CD1 2.85Å; H171-I175 WeakPolarHBondContact O-CG1 3.18Å; H171-I175 PolarHBondContact O-N 2.95Å; S172-I175 PolarHBondContact O-N 2.79Å; N173-I175 VanDerWaalsContact C-N 3.3Å; N173-I175 PolarHBondContact O-N 2.95Å; I175-V177 PolarHBondContact O-N 3.12Å; I175-S178 PolarHBondContact O-N 2.99Å; I175-L179 HydrophobicContact CG2-CD1 3.93Å; I175-L179 HydrophobicContact CG2-CG 4.39Å; I175-L179 WeakPolarHBondContact O-CG 3.4Å; I175-L179 PolarHBondContact O-N 2.93Å
176	V	89.1	Confident	84.2	Confident	0 Å²	0	50.5 Å²	50.5	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-58.2	-47.6	179.4	166.8	0	0	0	0	110.6	F94 L153 Q154 V157 S172 N173 S178 L179 Q180	F94-V176 HydrophobicContact CE2-CG2 4.09Å; F94-V176 HydrophobicContact CZ-CG2 4.29Å; L153-V176 HydrophobicContact CD2-CG2 3.8Å; L153-V176 HydrophobicContact CG-CG2 3.88Å; Q154-V176 HydrophobicContact CB-CG1 4.03Å; Q154-V176 HydrophobicContact CG-CG1 4.28Å; V157-V176 HydrophobicContact CG2-CG2 4.24Å; S172-V176 WeakPolarHBondContact O-CG2 3.38Å; S172-V176 PolarHBondContact O-N 3.42Å; S172-V176 VanDerWaalsContact O-N 3.07Å; N173-V176 WeakPolarHBondContact O-CB 3.24Å; N173-V176 PolarHBondContact O-N 3.4Å; N173-V176 VanDerWaalsContact O-N 3.12Å; V176-S178 PolarHBondContact O-N 3.4Å; V176-L179 PolarHBondContact O-N 3.05Å; V176-Q180 HydrophobicContact CG1-CG 4.47Å; V176-Q180 WeakPolarHBondContact O-CG 3.34Å; V176-Q180 PolarHBondContact O-N 3.38Å
177	V	85.6	Confident	85.1	Confident	5 Å²	5	40 Å²	40	3%	0.03	22%	0.22	C	C	.	.	H	α-helix	trans	-65.5	-39.5	177.3	-173.6	0	0	0	0	112.3	N173 I175 L179 Q180 S181 Q297 I301	N173-V177 WeakPolarHBondContact O-CG2 3.19Å; N173-V177 PolarHBondContact O-N 2.86Å; I175-V177 PolarHBondContact O-N 3.12Å; V177-L179 VanDerWaalsContact C-N 3.3Å; V177-L179 PolarHBondContact O-N 3.33Å; V177-Q180 PolarHBondContact O-N 3.49Å; V177-S181 WeakPolarHBondContact O-CB 3.49Å; V177-S181 PolarHBondContact O-N 3.18Å; V177-Q297 HydrophobicContact CG2-CB 3.44Å; V177-Q297 VanDerWaalsContact CG2-CB 3.44Å; V177-Q297 HydrophobicContact CG2-CG 4.07Å; V177-I301 HydrophobicContact CB-CD1 3.78Å; V177-I301 HydrophobicContact CG1-CD1 3.29Å; V177-I301 HydrophobicContact CG1-CG1 4.45Å; V177-I301 HydrophobicContact CG2-CD1 4.28Å
178	S	86.9	Confident	86	Confident	57 Å²	57	36.5 Å²	36.5	40%	0.399	21%	0.207	S	C	.	.	H	α-helix	trans	-60.1	-42.8	176.3	-173.6	0	0	0	0	111.5	T174 I175 V176 K182	T174-S178 WeakPolarHBondContact O-CB 3.36Å; T174-S178 PolarHBondContact O-N 2.86Å; I175-S178 PolarHBondContact O-N 2.99Å; V176-S178 PolarHBondContact O-N 3.4Å; S178-K182 VanDerWaalsContact O-CG 3.31Å; S178-K182 WeakPolarHBondContact O-CG 3.44Å; S178-K182 PolarHBondContact O-N 3.36Å; S178-K182 VanDerWaalsContact O-N 3.09Å
179	L	90.9	Very high	86.7	Confident	13 Å²	13	37.7 Å²	37.7	7%	0.068	21%	0.214	C	C	.	.	H	α-helix	trans	-65.9	-42	175.8	-68	171.9	0	0	0	111.7	A98 I101 L105 I150 L153 I175 V176 V177 K182 L183	A98-L179 HydrophobicContact CB-CD1 4.45Å; I101-L179 HydrophobicContact CB-CD1 4.4Å; I101-L179 HydrophobicContact CG2-CD1 4.05Å; I101-L179 HydrophobicContact CG2-CD2 4.22Å; L105-L179 HydrophobicContact CD2-CD2 4.35Å; I150-L179 HydrophobicContact CD1-CB 4.01Å; I150-L179 HydrophobicContact CG1-CB 4.37Å; L153-L179 HydrophobicContact CD2-CD1 4Å; I175-L179 HydrophobicContact CG2-CD1 3.93Å; I175-L179 HydrophobicContact CG2-CG 4.39Å; I175-L179 WeakPolarHBondContact O-CG 3.4Å; I175-L179 PolarHBondContact O-N 2.93Å; V176-L179 PolarHBondContact O-N 3.05Å; V177-L179 VanDerWaalsContact C-N 3.3Å; V177-L179 PolarHBondContact O-N 3.33Å; L179-K182 PolarHBondContact O-N 2.88Å; L179-L183 WeakPolarHBondContact O-CB 3.27Å; L179-L183 PolarHBondContact O-N 2.95Å
180	Q	89.8	Confident	87.4	Confident	0 Å²	0	36 Å²	36	0%	0	21%	0.206	C	C	.	.	H	α-helix	trans	-61.1	-46.7	176.4	-71.9	162.7	-3.1	0	0	111.9	I150 V176 V177 K182 L183 A184 L290 M293 V294	I150-Q180 HydrophobicContact CG2-CG 3.43Å; I150-Q180 VanDerWaalsContact CG2-CG 3.43Å; V176-Q180 HydrophobicContact CG1-CG 4.47Å; V176-Q180 WeakPolarHBondContact O-CG 3.34Å; V176-Q180 PolarHBondContact O-N 3.38Å; V177-Q180 PolarHBondContact O-N 3.49Å; Q180-K182 VanDerWaalsContact C-N 3.34Å; Q180-K182 PolarHBondContact O-N 3.32Å; Q180-L183 PolarHBondContact O-N 2.99Å; Q180-A184 WeakPolarHBondContact O-CB 3.47Å; Q180-A184 PolarHBondContact O-N 3.34Å; Q180-L290 HydrophobicContact CB-CD2 4.31Å; Q180-L290 HydrophobicContact CG-CD2 4.39Å; Q180-M293 HydrophobicContact CG-CG 4.26Å; Q180-M293 HydrophobicContact CG-SD 3.63Å; Q180-M293 PolarHBondContact NE2-SD 3.01Å; Q180-V294 HydrophobicContact CB-CG2 4.04Å
181	S	87.1	Confident	88.1	Confident	71 Å²	71	36.7 Å²	36.7	50%	0.497	21%	0.205	S	C	.	.	H	α-helix	trans	-60.2	-44.3	177.4	176.5	0	0	0	0	111.4	V177 A184 S185	V177-S181 WeakPolarHBondContact O-CB 3.49Å; V177-S181 PolarHBondContact O-N 3.18Å; S181-A184 PolarHBondContact O-N 2.89Å; S181-S185 PolarHBondContact O-N 2.89Å
182	K	88.2	Confident	88.6	Confident	106 Å²	106	35 Å²	35	46%	0.461	20%	0.204	S	C	.	.	H	α-helix	trans	-66	-39.7	176.2	-68.1	177.5	-177.9	-169.7	0	112.7	L105 F109 S178 L179 Q180 A184 S185 M186	L105-K182 HydrophobicContact CD2-CB 3.65Å; L105-K182 HydrophobicContact CD2-CD 3.88Å; L105-K182 HydrophobicContact CD2-CG 4.43Å; F109-K182 HydrophobicContact CE2-CB 4.48Å; S178-K182 VanDerWaalsContact O-CG 3.31Å; S178-K182 WeakPolarHBondContact O-CG 3.44Å; S178-K182 PolarHBondContact O-N 3.36Å; S178-K182 VanDerWaalsContact O-N 3.09Å; L179-K182 PolarHBondContact O-N 2.88Å; Q180-K182 VanDerWaalsContact C-N 3.34Å; Q180-K182 PolarHBondContact O-N 3.32Å; K182-A184 VanDerWaalsContact C-N 3.34Å; K182-S185 PolarHBondContact O-N 3.41Å; K182-M186 WeakPolarHBondContact O-CB 3.39Å; K182-M186 PolarHBondContact O-N 3.45Å
183	L	92	Very high	88.8	Confident	0 Å²	0	35.1 Å²	35.1	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-64.9	-39	175	-177.3	64.3	0	0	0	111.5	L105 I143 L146 N147 I150 L179 Q180 M186 S187 L290	L105-L183 HydrophobicContact CD1-CB 4.35Å; L105-L183 HydrophobicContact CD1-CD1 4.22Å; I143-L183 HydrophobicContact CG1-CD1 4.47Å; I143-L183 HydrophobicContact CG2-CD1 4.22Å; L146-L183 HydrophobicContact CB-CD1 3.9Å; L146-L183 HydrophobicContact CB-CD2 4.3Å; L146-L183 HydrophobicContact CD1-CD1 4.11Å; N147-L183 HydrophobicContact CB-CD2 3.96Å; I150-L183 HydrophobicContact CD1-CB 4.13Å; I150-L183 HydrophobicContact CD1-CD2 3.8Å; L179-L183 WeakPolarHBondContact O-CB 3.27Å; L179-L183 PolarHBondContact O-N 2.95Å; Q180-L183 PolarHBondContact O-N 2.99Å; L183-M186 PolarHBondContact O-N 2.96Å; L183-S187 WeakPolarHBondContact O-CB 3.41Å; L183-S187 PolarHBondContact O-N 2.93Å; L183-S187 PolarHBondContact O-OG 3.36Å; L183-L290 HydrophobicContact CB-CD1 4.46Å; L183-L290 HydrophobicContact CD2-CD1 4.22Å; L183-L290 HydrophobicContact CD2-CD2 4.17Å; L183-L290 HydrophobicContact CG-CD1 4.09Å
184	A	89.1	Confident	89.2	Confident	21 Å²	21	33.6 Å²	33.6	17%	0.174	20%	0.195	C	C	.	.	H	α-helix	trans	-63.8	-44	175.2	0	0	0	0	0	111.3	Q180 S181 K182 S187 N188 L290	Q180-A184 WeakPolarHBondContact O-CB 3.47Å; Q180-A184 PolarHBondContact O-N 3.34Å; S181-A184 PolarHBondContact O-N 2.89Å; K182-A184 VanDerWaalsContact C-N 3.34Å; A184-S187 PolarHBondContact O-N 3.08Å; A184-N188 PolarHBondContact O-N 2.91Å; A184-L290 HydrophobicContact CB-CB 4.47Å; A184-L290 HydrophobicContact CB-CD1 3.95Å
185	S	86.5	Confident	89.5	Confident	59 Å²	59	35.7 Å²	35.7	41%	0.413	20%	0.202	S	C	.	.	H	α-helix	trans	-59.7	-49.5	173.6	-167.1	0	0	0	0	111.4	S181 K182 S187 N188 D189	S181-S185 PolarHBondContact O-N 2.89Å; K182-S185 PolarHBondContact O-N 3.41Å; S185-S187 VanDerWaalsContact C-N 3.29Å; S185-S187 PolarHBondContact O-N 3.02Å; S185-N188 WeakPolarHBondContact O-CB 3.46Å; S185-N188 PolarHBondContact O-N 2.63Å; S185-N188 VanDerWaalsContact O-N 3.08Å; S185-D189 PolarHBondContact O-N 2.76Å
186	M	89.3	Confident	89.6	Confident	0 Å²	0	36.3 Å²	36.3	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-57.2	-43.2	177.4	-176.1	-172	-73.3	0	0	112.2	L105 T108 F109 L112 I143 K182 L183 N188 D189 F190	L105-M186 HydrophobicContact CD1-CE 3.4Å; L105-M186 VanDerWaalsContact CD1-CE 3.4Å; L105-M186 HydrophobicContact CD1-SD 4.2Å; L105-M186 HydrophobicContact CG-CE 3.85Å; L105-M186 WeakPolarHBondContact O-CE 3.33Å; T108-M186 HydrophobicContact CG2-CE 4.17Å; T108-M186 HydrophobicContact CG2-SD 3.49Å; T108-M186 WeakPolarHBondContact CG2-SD 3.43Å; F109-M186 HydrophobicContact CB-CE 4.04Å; F109-M186 HydrophobicContact CD1-CB 4.42Å; F109-M186 HydrophobicContact CD1-CE 3.92Å; F109-M186 HydrophobicContact CD1-CG 4.28Å; F109-M186 HydrophobicContact CD2-CE 3.12Å; F109-M186 HydrophobicContact CE1-CB 3.73Å; F109-M186 HydrophobicContact CE1-CE 4.15Å; F109-M186 HydrophobicContact CE1-CG 4.06Å; F109-M186 HydrophobicContact CE2-CB 4.17Å; F109-M186 HydrophobicContact CE2-CE 3.4Å; F109-M186 HydrophobicContact CG-CE 3.41Å; F109-M186 VanDerWaalsContact CG-CE 3.41Å; F109-M186 HydrophobicContact CZ-CB 3.58Å; F109-M186 HydrophobicContact CZ-CE 3.91Å; F109-M186 HydrophobicContact CZ-CG 4.25Å; L112-M186 HydrophobicContact CD2-CG 3.7Å; L112-M186 WeakPolarHBondContact CD2-O 3.18Å; I143-M186 HydrophobicContact CD1-CG 4.46Å; I143-M186 HydrophobicContact CD1-SD 4.41Å; I143-M186 HydrophobicContact CG1-SD 4Å; K182-M186 WeakPolarHBondContact O-CB 3.39Å; K182-M186 PolarHBondContact O-N 3.45Å; L183-M186 PolarHBondContact O-N 2.96Å; M186-N188 VanDerWaalsContact C-N 3.28Å; M186-N188 PolarHBondContact O-N 3.22Å; M186-D189 PolarHBondContact O-N 2.92Å; M186-F190 WeakPolarHBondContact O-CB 3.38Å; M186-F190 PolarHBondContact O-N 3.39Å
187	S	92.1	Very high	89.4	Confident	0 Å²	0	36.8 Å²	36.8	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-65.2	-35.5	179.2	-57.6	0	0	0	0	111.2	L183 A184 S185 K191 F287	L183-S187 WeakPolarHBondContact O-CB 3.41Å; L183-S187 PolarHBondContact O-N 2.93Å; L183-S187 PolarHBondContact O-OG 3.36Å; A184-S187 PolarHBondContact O-N 3.08Å; S185-S187 VanDerWaalsContact C-N 3.29Å; S185-S187 PolarHBondContact O-N 3.02Å; S187-K191 WeakPolarHBondContact O-CB 3.09Å; S187-K191 PolarHBondContact O-N 3.28Å; S187-F287 WeakPolarHBondContact O-CZ 3.32Å
188	N	89.4	Confident	89.5	Confident	79 Å²	79	37.6 Å²	37.6	42%	0.422	22%	0.215	S	C	.	.	H	α-helix	trans	-68.5	-47.1	176	-94.1	-44.3	0	0	0	111.2	A184 S185 M186 F190 K191 S192 F287	A184-N188 PolarHBondContact O-N 2.91Å; S185-N188 WeakPolarHBondContact O-CB 3.46Å; S185-N188 PolarHBondContact O-N 2.63Å; S185-N188 VanDerWaalsContact O-N 3.08Å; M186-N188 VanDerWaalsContact C-N 3.28Å; M186-N188 PolarHBondContact O-N 3.22Å; N188-F190 VanDerWaalsContact C-N 3.28Å; N188-F190 PolarHBondContact O-N 2.76Å; N188-K191 PolarHBondContact O-N 3.33Å; N188-S192 PolarHBondContact O-N 3.28Å; N188-S192 PolarHBondContact O-OG 2.93Å; N188-F287 HydrophobicContact CB-CE1 4.2Å; N188-F287 HydrophobicContact CB-CZ 4.09Å; N188-F287 VanDerWaalsContact CG-CE1 3.43Å; N188-F287 VanDerWaalsContact N-CZ 3.32Å; N188-F287 WeakPolarHBondContact ND2-CE1 3.07Å; N188-F287 WeakPolarHBondContact OD1-CE1 3.11Å; N188-F287 VanDerWaalsContact OD1-CZ 3.25Å; N188-F287 WeakPolarHBondContact OD1-CZ 3.49Å
189	D	87.4	Confident	89.6	Confident	74 Å²	74	39.1 Å²	39.1	40%	0.396	22%	0.216	S	C	.	.	H	α-helix	trans	-59.2	-43.1	176.1	-67	-25.4	0	0	0	110.8	L112 S185 M186 S192 V193	L112-D189 HydrophobicContact CD2-CB 3.77Å; S185-D189 PolarHBondContact O-N 2.76Å; M186-D189 PolarHBondContact O-N 2.92Å; D189-S192 PolarHBondContact O-N 3.46Å; D189-V193 WeakPolarHBondContact O-CG2 3.32Å; D189-V193 PolarHBondContact O-N 2.92Å
190	F	93.8	Very high	89.3	Confident	0 Å²	0	39.8 Å²	39.8	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-61.9	-46.5	175.5	-176.5	-134.3	0	0	0	112.5	L112 L115 T136 I139 I143 M186 N188 S192 V193 L194 T279 L283	L112-F190 HydrophobicContact CD1-CB 3.78Å; L112-F190 HydrophobicContact CD1-CD2 3.79Å; L112-F190 HydrophobicContact CD1-CG 4.22Å; L112-F190 HydrophobicContact CD2-CB 4.25Å; L115-F190 HydrophobicContact CD2-CD2 3.92Å; L115-F190 HydrophobicContact CD2-CE2 3.63Å; T136-F190 HydrophobicContact CG2-CE2 4.31Å; T136-F190 HydrophobicContact CG2-CZ 3.96Å; I139-F190 HydrophobicContact CB-CE2 4.12Å; I139-F190 HydrophobicContact CB-CZ 4.2Å; I139-F190 HydrophobicContact CD1-CE2 4.46Å; I139-F190 HydrophobicContact CG2-CD1 3.98Å; I139-F190 HydrophobicContact CG2-CD2 3.79Å; I139-F190 HydrophobicContact CG2-CE1 4.03Å; I139-F190 HydrophobicContact CG2-CE2 3.83Å; I139-F190 HydrophobicContact CG2-CG 3.87Å; I139-F190 HydrophobicContact CG2-CZ 3.95Å; I143-F190 HydrophobicContact CD1-CB 4.23Å; I143-F190 HydrophobicContact CD1-CD1 3.65Å; I143-F190 HydrophobicContact CD1-CE1 4.33Å; I143-F190 HydrophobicContact CD1-CG 4.18Å; M186-F190 WeakPolarHBondContact O-CB 3.38Å; M186-F190 PolarHBondContact O-N 3.39Å; N188-F190 VanDerWaalsContact C-N 3.28Å; N188-F190 PolarHBondContact O-N 2.76Å; F190-S192 PolarHBondContact O-N 3.45Å; F190-V193 PolarHBondContact O-N 2.96Å; F190-L194 HydrophobicContact CD1-CD1 4.36Å; F190-L194 HydrophobicContact CD2-CD1 4.41Å; F190-L194 HydrophobicContact CD2-CG 4.2Å; F190-L194 HydrophobicContact CE1-CD1 3.96Å; F190-L194 HydrophobicContact CE2-CD1 4.02Å; F190-L194 HydrophobicContact CE2-CD2 4Å; F190-L194 HydrophobicContact CE2-CG 3.95Å; F190-L194 HydrophobicContact CZ-CD1 3.78Å; F190-L194 HydrophobicContact CZ-CD2 4.35Å; F190-L194 HydrophobicContact CZ-CG 4.23Å; F190-L194 WeakPolarHBondContact O-CG 3.26Å; F190-L194 PolarHBondContact O-N 3.36Å; F190-T279 HydrophobicContact CE1-CG2 3.83Å; F190-T279 HydrophobicContact CZ-CG2 4.12Å; F190-L283 HydrophobicContact CD1-CD1 3.4Å; F190-L283 VanDerWaalsContact CD1-CD1 3.4Å; F190-L283 HydrophobicContact CD1-CD2 3.93Å; F190-L283 HydrophobicContact CD1-CG 4.24Å; F190-L283 HydrophobicContact CE1-CD1 3.77Å; F190-L283 HydrophobicContact CE1-CD2 4.31Å; F190-L283 HydrophobicContact CE1-CG 4.45Å; F190-L283 HydrophobicContact CG-CD1 4.35Å
191	K	92.9	Very high	89	Confident	61 Å²	61	40.3 Å²	40.3	27%	0.265	22%	0.222	S	C	.	.	H	α-helix	trans	-57	-47.6	173.8	176.4	174.6	177.6	-74.9	0	111.8	S187 N188 V193 L194 E195 I280 L283 F287	S187-K191 WeakPolarHBondContact O-CB 3.09Å; S187-K191 PolarHBondContact O-N 3.28Å; N188-K191 PolarHBondContact O-N 3.33Å; K191-V193 VanDerWaalsContact C-N 3.31Å; K191-V193 PolarHBondContact O-N 3.3Å; K191-L194 WeakPolarHBondContact O-CB 3.34Å; K191-L194 PolarHBondContact O-N 3.46Å; K191-E195 WeakPolarHBondContact CE-OE1 3.46Å; K191-E195 IonicContact NZ-OE1 2.77Å; K191-E195 PolarHBondContact NZ-OE1 2.89Å; K191-E195 WeakPolarHBondContact O-CG 3.38Å; K191-E195 PolarHBondContact O-N 2.97Å; K191-I280 HydrophobicContact CD-CG2 4.43Å; K191-I280 HydrophobicContact CG-CG2 4.31Å; K191-L283 HydrophobicContact CB-CD1 4.41Å; K191-F287 HydrophobicContact CD-CE2 4.04Å
192	S	90.2	Very high	89	Confident	60 Å²	60	43 Å²	43	42%	0.42	23%	0.225	S	C	.	.	H	α-helix	trans	-62.4	-37.6	178.9	-66.4	0	0	0	0	112.7	N188 D189 F190 E195 V196	N188-S192 PolarHBondContact O-N 3.28Å; N188-S192 PolarHBondContact O-OG 2.93Å; D189-S192 PolarHBondContact O-N 3.46Å; F190-S192 PolarHBondContact O-N 3.45Å; S192-E195 PolarHBondContact O-N 3.45Å; S192-V196 VanDerWaalsContact O-CG2 3.3Å; S192-V196 WeakPolarHBondContact O-CG2 3.36Å; S192-V196 PolarHBondContact O-N 3.45Å
193	V	90.6	Very high	88.8	Confident	12 Å²	12	41.2 Å²	41.2	7%	0.073	22%	0.218	C	C	.	.	H	α-helix	trans	-65.5	-42.4	175.5	171.2	0	0	0	0	111.4	L112 L115 T116 A119 D189 F190 K191 V196 R197	L112-V193 HydrophobicContact CD1-CG2 4.38Å; L115-V193 HydrophobicContact CD2-CG1 3.98Å; L115-V193 HydrophobicContact CG-CG1 3.82Å; T116-V193 HydrophobicContact CG2-CG2 3.98Å; T116-V193 WeakPolarHBondContact OG1-CG2 3.32Å; A119-V193 HydrophobicContact CB-CG1 3.65Å; D189-V193 WeakPolarHBondContact O-CG2 3.32Å; D189-V193 PolarHBondContact O-N 2.92Å; F190-V193 PolarHBondContact O-N 2.96Å; K191-V193 VanDerWaalsContact C-N 3.31Å; K191-V193 PolarHBondContact O-N 3.3Å; V193-V196 PolarHBondContact O-N 3.01Å; V193-R197 PolarHBondContact O-N 3.39Å
194	L	91.2	Very high	88.2	Confident	2 Å²	2	43 Å²	43	1%	0.01	23%	0.227	C	C	.	.	H	α-helix	trans	-63.5	-42.5	175.1	-71.2	-175.3	0	0	0	112.1	T136 F190 K191 V196 R197 T198 I276 T279 I280 L283	T136-L194 HydrophobicContact CG2-CD2 3.84Å; F190-L194 HydrophobicContact CD1-CD1 4.36Å; F190-L194 HydrophobicContact CD2-CD1 4.41Å; F190-L194 HydrophobicContact CD2-CG 4.2Å; F190-L194 HydrophobicContact CE1-CD1 3.96Å; F190-L194 HydrophobicContact CE2-CD1 4.02Å; F190-L194 HydrophobicContact CE2-CD2 4Å; F190-L194 HydrophobicContact CE2-CG 3.95Å; F190-L194 HydrophobicContact CZ-CD1 3.78Å; F190-L194 HydrophobicContact CZ-CD2 4.35Å; F190-L194 HydrophobicContact CZ-CG 4.23Å; F190-L194 WeakPolarHBondContact O-CG 3.26Å; F190-L194 PolarHBondContact O-N 3.36Å; K191-L194 WeakPolarHBondContact O-CB 3.34Å; K191-L194 PolarHBondContact O-N 3.46Å; L194-V196 PolarHBondContact O-N 3.25Å; L194-R197 WeakPolarHBondContact O-CB 3.38Å; L194-R197 PolarHBondContact O-N 3.13Å; L194-R197 VanDerWaalsContact O-N 3.13Å; L194-T198 PolarHBondContact O-N 3.39Å; L194-T198 PolarHBondContact O-OG1 3.46Å; L194-T198 VanDerWaalsContact O-OG1 3.1Å; L194-I276 HydrophobicContact CB-CG2 3.76Å; L194-I276 HydrophobicContact CD1-CG2 4.33Å; L194-I276 HydrophobicContact CD2-CG1 4.27Å; L194-I276 HydrophobicContact CD2-CG2 4.03Å; L194-I276 HydrophobicContact CG-CG2 4.25Å; L194-T279 HydrophobicContact CD1-CG2 3.83Å; L194-I280 HydrophobicContact CB-CD1 4.03Å; L194-I280 HydrophobicContact CB-CG1 4.03Å; L194-I280 HydrophobicContact CD1-CG1 4Å; L194-L283 HydrophobicContact CD1-CD1 4.29Å
195	E	91.1	Very high	87.9	Confident	85 Å²	85	47.4 Å²	47.4	40%	0.397	24%	0.239	S	C	.	.	H	α-helix	trans	-60.5	-44.6	174.7	-73.8	171.8	170.3	0	0	111.9	K191 S192 R197 T198 E199 I280	K191-E195 WeakPolarHBondContact CE-OE1 3.46Å; K191-E195 IonicContact NZ-OE1 2.77Å; K191-E195 PolarHBondContact NZ-OE1 2.89Å; K191-E195 WeakPolarHBondContact O-CG 3.38Å; K191-E195 PolarHBondContact O-N 2.97Å; S192-E195 PolarHBondContact O-N 3.45Å; E195-R197 VanDerWaalsContact C-N 3.28Å; E195-R197 PolarHBondContact O-N 3.28Å; E195-T198 PolarHBondContact O-N 3.3Å; E195-E199 WeakPolarHBondContact O-CB 3.37Å; E195-E199 PolarHBondContact O-N 3.42Å; E195-I280 HydrophobicContact CG-CD1 4.29Å
196	V	88.6	Confident	87.8	Confident	58 Å²	58	47 Å²	47	35%	0.352	24%	0.236	S	C	.	.	H	α-helix	trans	-60.2	-40.1	174.2	169.1	0	0	0	0	110.9	S192 V193 L194 E199 N200	S192-V196 VanDerWaalsContact O-CG2 3.3Å; S192-V196 WeakPolarHBondContact O-CG2 3.36Å; S192-V196 PolarHBondContact O-N 3.45Å; V193-V196 PolarHBondContact O-N 3.01Å; L194-V196 PolarHBondContact O-N 3.25Å; V196-E199 PolarHBondContact O-N 3.33Å; V196-N200 WeakPolarHBondContact O-CB 3.48Å; V196-N200 PolarHBondContact O-N 2.85Å; V196-N200 PolarHBondContact O-ND2 3.28Å
197	R	85.2	Confident	87.5	Confident	10 Å²	10	53.4 Å²	53.4	4%	0.038	26%	0.26	C	S	.	.	H	α-helix	trans	-65.7	-45.3	177.5	-179.8	55	172.8	150.2	-17.1	111.9	A119 D127 I132 V193 L194 E195 E199 N200 L201 I276	A119-R197 HydrophobicContact CB-CB 4.46Å; D127-R197 VanDerWaalsContact CG-NH2 3.27Å; D127-R197 IonicContact OD1-CZ 3.69Å; D127-R197 IonicContact OD1-NH1 3.48Å; D127-R197 IonicContact OD1-NH2 2.77Å; D127-R197 PolarHBondContact OD1-NH2 3.33Å; D127-R197 IonicContact OD2-CZ 4Å; D127-R197 IonicContact OD2-NH1 3.42Å; D127-R197 PolarHBondContact OD2-NH1 3.32Å; D127-R197 IonicContact OD2-NH2 2.63Å; D127-R197 PolarHBondContact OD2-NH2 3.04Å; I132-R197 HydrophobicContact CG2-CG 4.38Å; V193-R197 PolarHBondContact O-N 3.39Å; L194-R197 WeakPolarHBondContact O-CB 3.38Å; L194-R197 PolarHBondContact O-N 3.13Å; L194-R197 VanDerWaalsContact O-N 3.13Å; E195-R197 VanDerWaalsContact C-N 3.28Å; E195-R197 PolarHBondContact O-N 3.28Å; R197-E199 VanDerWaalsContact C-N 3.33Å; R197-E199 PolarHBondContact O-N 2.9Å; R197-N200 PolarHBondContact O-N 2.88Å; R197-L201 HydrophobicContact CG-CD1 3.98Å; R197-L201 WeakPolarHBondContact O-CD1 3.04Å; R197-L201 PolarHBondContact O-N 3.09Å; R197-I276 HydrophobicContact CB-CD1 4.44Å; R197-I276 HydrophobicContact CG-CD1 3.75Å
198	T	88.3	Confident	86.7	Confident	22 Å²	22	59.9 Å²	59.9	14%	0.135	29%	0.285	C	S	.	.	H	α-helix	trans	-58.9	-44.5	175.6	-60.4	0	0	0	0	111.3	L194 E195 N200 L201 K202 M273 I276	L194-T198 PolarHBondContact O-N 3.39Å; L194-T198 PolarHBondContact O-OG1 3.46Å; L194-T198 VanDerWaalsContact O-OG1 3.1Å; E195-T198 PolarHBondContact O-N 3.3Å; T198-N200 PolarHBondContact O-N 3.49Å; T198-L201 PolarHBondContact O-N 3.41Å; T198-K202 WeakPolarHBondContact O-CB 3.37Å; T198-K202 PolarHBondContact O-N 3.06Å; T198-M273 HydrophobicContact CG2-CE 3.79Å; T198-M273 HydrophobicContact CG2-CG 4.14Å; T198-M273 HydrophobicContact CG2-SD 4.15Å; T198-I276 WeakPolarHBondContact OG1-CG2 3.4Å
199	E	88.6	Confident	86.3	Confident	89 Å²	89	60.5 Å²	60.5	42%	0.416	29%	0.285	S	S	.	.	H	α-helix	trans	-64.6	-40.8	177.3	-176.6	55.8	-150.1	0	0	111.8	E195 V196 R197 L201 K202 Q203	E195-E199 WeakPolarHBondContact O-CB 3.37Å; E195-E199 PolarHBondContact O-N 3.42Å; V196-E199 PolarHBondContact O-N 3.33Å; R197-E199 VanDerWaalsContact C-N 3.33Å; R197-E199 PolarHBondContact O-N 2.9Å; E199-L201 PolarHBondContact O-N 2.94Å; E199-K202 PolarHBondContact O-N 3.04Å; E199-Q203 WeakPolarHBondContact O-CB 3.35Å; E199-Q203 WeakPolarHBondContact O-CG 3.47Å; E199-Q203 PolarHBondContact O-N 2.85Å; E199-Q203 PolarHBondContact OE1-NE2 3.26Å
200	N	84.6	Confident	85.8	Confident	27 Å²	27	63.3 Å²	63.3	14%	0.144	30%	0.296	C	S	.	.	H	α-helix	trans	-62.7	-41.9	174.8	-80.3	-53.7	0	0	0	112.6	A119 V196 R197 T198 Q203 Q204	A119-N200 PolarHBondContact O-ND2 2.91Å; V196-N200 WeakPolarHBondContact O-CB 3.48Å; V196-N200 PolarHBondContact O-N 2.85Å; V196-N200 PolarHBondContact O-ND2 3.28Å; R197-N200 PolarHBondContact O-N 2.88Å; T198-N200 PolarHBondContact O-N 3.49Å; N200-Q203 PolarHBondContact O-N 3.41Å; N200-Q204 PolarHBondContact O-N 3.37Å
201	L	83.6	Confident	84.8	Confident	10 Å²	10	70.9 Å²	70.9	5%	0.052	33%	0.329	C	S	.	.	H	α-helix	trans	-62	-44.3	175.2	-80.4	151.3	0	0	0	111.2	R197 T198 E199 Q204 R205 R269 I276	R197-L201 HydrophobicContact CG-CD1 3.98Å; R197-L201 WeakPolarHBondContact O-CD1 3.04Å; R197-L201 PolarHBondContact O-N 3.09Å; T198-L201 PolarHBondContact O-N 3.41Å; E199-L201 PolarHBondContact O-N 2.94Å; L201-Q204 PolarHBondContact O-N 2.84Å; L201-R205 PolarHBondContact O-N 3.33Å; L201-R269 HydrophobicContact CD2-CB 4.21Å; L201-R269 HydrophobicContact CD2-CG 4.23Å; L201-I276 HydrophobicContact CD1-CD1 4.1Å
202	K	85.9	Confident	83.6	Confident	127 Å²	127	70.7 Å²	70.7	55%	0.552	34%	0.335	S	S	*	.	H	α-helix	trans	-63.3	-43.4	177.1	-173	-179.8	179.1	-177.1	0	112	T198 E199 R205 S206	T198-K202 WeakPolarHBondContact O-CB 3.37Å; T198-K202 PolarHBondContact O-N 3.06Å; E199-K202 PolarHBondContact O-N 3.04Å; K202-R205 PolarHBondContact O-N 3.09Å; K202-S206 WeakPolarHBondContact O-CB 3.38Å; K202-S206 PolarHBondContact O-N 3.38Å
203	Q	84.9	Confident	82	Confident	70 Å²	70	78 Å²	78	33%	0.327	35%	0.354	S	S	.	.	H	α-helix	trans	-65	-39.8	175.9	-73.3	178.5	23.4	0	0	112.1	E199 N200 S206 R207	E199-Q203 WeakPolarHBondContact O-CB 3.35Å; E199-Q203 WeakPolarHBondContact O-CG 3.47Å; E199-Q203 PolarHBondContact O-N 2.85Å; E199-Q203 PolarHBondContact OE1-NE2 3.26Å; N200-Q203 PolarHBondContact O-N 3.41Å; Q203-S206 PolarHBondContact O-N 3.4Å; Q203-R207 WeakPolarHBondContact O-CB 3.25Å; Q203-R207 WeakPolarHBondContact O-CG 3.39Å; Q203-R207 PolarHBondContact O-N 2.78Å
204	Q	79.6	Confident	79.9	Confident	38 Å²	38	80.4 Å²	80.4	18%	0.178	38%	0.375	C	S	.	.	H	α-helix	trans	-61.6	-46.8	173	-84.8	-174	-4.9	0	0	111.7	L124 N200 L201 R208	L124-Q204 HydrophobicContact CD2-CG 3.75Å; N200-Q204 PolarHBondContact O-N 3.37Å; L201-Q204 PolarHBondContact O-N 2.84Å; Q204-R208 WeakPolarHBondContact O-CB 3.31Å; Q204-R208 PolarHBondContact O-N 3.46Å
205	R	81.8	Confident	77.9	Confident	112 Å²	112	84.7 Å²	84.7	42%	0.423	40%	0.403	S	S	.	.	H	α-helix	trans	-60.5	-48.4	176.5	-176.9	-171.9	-95	-148.2	-1	111.1	L201 K202 R207 R208 E209	L201-R205 PolarHBondContact O-N 3.33Å; K202-R205 PolarHBondContact O-N 3.09Å; R205-R207 PolarHBondContact O-N 2.95Å; R205-R208 WeakPolarHBondContact O-CB 3.33Å; R205-R208 PolarHBondContact O-N 3Å; R205-R208 VanDerWaalsContact O-N 3.16Å; R205-E209 WeakPolarHBondContact CD-OE1 3.2Å; R205-E209 HydrophobicContact CG-CG 4.4Å; R205-E209 VanDerWaalsContact CG-OE1 3.32Å; R205-E209 WeakPolarHBondContact CG-OE1 3.47Å; R205-E209 WeakPolarHBondContact O-CG 3.44Å; R205-E209 PolarHBondContact O-N 3.26Å
206	S	85.4	Confident	76	Confident	51 Å²	51	86.1 Å²	86.1	36%	0.357	42%	0.417	S	S	.	.	H	α-helix	trans	-61.6	-44.5	-179.6	179.6	0	0	0	0	112.6	K202 Q203 E209 Q210	K202-S206 WeakPolarHBondContact O-CB 3.38Å; K202-S206 PolarHBondContact O-N 3.38Å; Q203-S206 PolarHBondContact O-N 3.4Å; S206-E209 PolarHBondContact O-N 3.28Å; S206-Q210 VanDerWaalsContact O-CG 3.3Å; S206-Q210 WeakPolarHBondContact O-CG 3.45Å; S206-Q210 PolarHBondContact O-N 2.93Å
207	R	81.8	Confident	74.2	Confident	134 Å²	134	89 Å²	89	51%	0.506	44%	0.44	S	S	.	.	H	α-helix	trans	-62.2	-44.5	173.6	-72.4	178.8	-172.7	-169	2.6	111	Q203 R205 E209 Q210 F211	Q203-R207 WeakPolarHBondContact O-CB 3.25Å; Q203-R207 WeakPolarHBondContact O-CG 3.39Å; Q203-R207 PolarHBondContact O-N 2.78Å; R205-R207 PolarHBondContact O-N 2.95Å; R207-E209 PolarHBondContact O-N 2.7Å; R207-Q210 WeakPolarHBondContact O-CB 3.38Å; R207-Q210 PolarHBondContact O-N 3.43Å; R207-F211 HydrophobicContact CB-CD2 4.41Å; R207-F211 HydrophobicContact CB-CE2 4.39Å; R207-F211 WeakPolarHBondContact O-CD2 3.42Å; R207-F211 PolarHBondContact O-N 3.5Å
208	R	76.8	Confident	72.2	Confident	137 Å²	137	91.8 Å²	91.8	52%	0.517	47%	0.465	S	S	.	.	H	α-helix	trans	-56.7	-52	176	176.4	67.8	73.2	-163.2	5.1	110.1	Q204 R205 Q210 F211 S212	Q204-R208 WeakPolarHBondContact O-CB 3.31Å; Q204-R208 PolarHBondContact O-N 3.46Å; R205-R208 WeakPolarHBondContact O-CB 3.33Å; R205-R208 PolarHBondContact O-N 3Å; R205-R208 VanDerWaalsContact O-N 3.16Å; R208-Q210 PolarHBondContact O-N 3.43Å; R208-F211 CarbonylContact O-C 3.52Å; R208-F211 PolarHBondContact O-N 2.9Å; R208-S212 WeakPolarHBondContact O-CA 3.43Å; R208-S212 WeakPolarHBondContact O-CB 3.11Å; R208-S212 PolarHBondContact O-N 3.41Å; R208-S212 PolarHBondContact O-OG 3.09Å
209	E	80	Confident	70.1	Confident	91 Å²	91	97.5 Å²	97.5	43%	0.425	49%	0.494	S	S	.	.	H	α-helix	trans	-57.2	-35.2	178.7	-72.5	172.2	-168.2	0	0	112.9	R205 S206 R207 R213	R205-E209 WeakPolarHBondContact CD-OE1 3.2Å; R205-E209 HydrophobicContact CG-CG 4.4Å; R205-E209 VanDerWaalsContact CG-OE1 3.32Å; R205-E209 WeakPolarHBondContact CG-OE1 3.47Å; R205-E209 WeakPolarHBondContact O-CG 3.44Å; R205-E209 PolarHBondContact O-N 3.26Å; S206-E209 PolarHBondContact O-N 3.28Å; R207-E209 PolarHBondContact O-N 2.7Å; E209-R213 VanDerWaalsContact O-CB 3.28Å; E209-R213 WeakPolarHBondContact O-CB 3.35Å; E209-R213 PolarHBondContact O-N 2.98Å
210	Q	77.4	Confident	68	Low	134 Å²	134	98.7 Å²	98.7	63%	0.626	51%	0.509	S	S	*	.	H	α-helix	trans	-70.1	-34.3	175.9	-72.9	171.5	-2.3	0	0	113.1	S206 R207 R208	S206-Q210 VanDerWaalsContact O-CG 3.3Å; S206-Q210 WeakPolarHBondContact O-CG 3.45Å; S206-Q210 PolarHBondContact O-N 2.93Å; R207-Q210 WeakPolarHBondContact O-CB 3.38Å; R207-Q210 PolarHBondContact O-N 3.43Å; R208-Q210 PolarHBondContact O-N 3.43Å
211	F	72.7	Confident	66.3	Low	159 Å²	159	105 Å²	105	70%	0.697	54%	0.542	S	S	*	.	H	α-helix	trans	-99.3	-18.8	-178.1	-64.2	-65.2	0	0	0	114.1	R207 R208	R207-F211 HydrophobicContact CB-CD2 4.41Å; R207-F211 HydrophobicContact CB-CE2 4.39Å; R207-F211 WeakPolarHBondContact O-CD2 3.42Å; R207-F211 PolarHBondContact O-N 3.5Å; R208-F211 CarbonylContact O-C 3.52Å; R208-F211 PolarHBondContact O-N 2.9Å
212	S	67.3	Low	64.2	Low	56 Å²	56	108.9 Å²	108.9	39%	0.392	58%	0.575	S	S	.	*	H	α-helix	trans	-91.3	-18.6	176.7	70	0	0	0	0	112.5	R208 A214	R208-S212 WeakPolarHBondContact O-CA 3.43Å; R208-S212 WeakPolarHBondContact O-CB 3.11Å; R208-S212 PolarHBondContact O-N 3.41Å; R208-S212 PolarHBondContact O-OG 3.09Å; S212-A214 PolarHBondContact O-N 3.07Å
213	R	56.6	Low	62.2	Low	214 Å²	214	108.2 Å²	108.2	81%	0.808	58%	0.584	S	S	*	*			trans	-74.7	33.3	162.6	-88.3	-177.3	144.8	150	-4.2	113.1	E209	E209-R213 VanDerWaalsContact O-CB 3.28Å; E209-R213 WeakPolarHBondContact O-CB 3.35Å; E209-R213 PolarHBondContact O-N 2.98Å
214	A	47.6	Very low	60.4	Low	63 Å²	63	113.3 Å²	113.3	52%	0.521	61%	0.614	S	S	.	*			trans	-66.2	128.2	160	0	0	0	0	0	107.4	S212 V216	S212-A214 PolarHBondContact O-N 3.07Å; A214-V216 PolarHBondContact O-N 3.45Å
215	P	47.6	Very low	58.5	Low	92 Å²	92	118.9 Å²	118.9	60%	0.597	64%	0.639	S	S	*	*			trans	-70.2	103.6	-172.4	28.9	-32.6	0	0	0	109.1	S217 A218	P215-S217 PolarHBondContact O-N 3.24Å; P215-S217 VanDerWaalsContact O-N 3.1Å; P215-A218 HydrophobicContact CB-CB 4.4Å; P215-A218 HydrophobicContact CG-CB 4.11Å; P215-A218 PolarHBondContact O-N 2.77Å; P215-A218 VanDerWaalsContact O-N 3.11Å
216	V	51.8	Low	56.4	Low	114 Å²	114	120.7 Å²	120.7	69%	0.691	66%	0.657	S	S	*	*	T	Hydrogen-bonded Turn	trans	-64	-2	158	-69.2	0	0	0	0	111.9	A214 A218	A214-V216 PolarHBondContact O-N 3.45Å; V216-A218 VanDerWaalsContact C-N 3.32Å
217	S	50.2	Low	54.1	Low	119 Å²	119	122.2 Å²	122.2	83%	0.832	68%	0.68	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.4	6.1	167.2	-60.2	0	0	0	0	114.9	P215	P215-S217 PolarHBondContact O-N 3.24Å; P215-S217 VanDerWaalsContact O-N 3.1Å
218	A	44.3	Very low	51.8	Low	68 Å²	68	119.8 Å²	119.8	56%	0.562	70%	0.698	S	S	*	*			trans	-120	51.1	176	0	0	0	0	0	112.3	P215 V216 P220	P215-A218 HydrophobicContact CB-CB 4.4Å; P215-A218 HydrophobicContact CG-CB 4.11Å; P215-A218 PolarHBondContact O-N 2.77Å; P215-A218 VanDerWaalsContact O-N 3.11Å; V216-A218 VanDerWaalsContact C-N 3.32Å; A218-P220 WeakPolarHBondContact O-CD 3.23Å
219	L	44.7	Very low	49.9	Very low	143 Å²	143	117.1 Å²	117.1	75%	0.749	71%	0.712	S	S	*	*			trans	-85.9	109.1	145.2	-83.3	130.8	0	0	0	106.4	L221	L219-L221 WeakPolarHBondContact O-CD1 3.43Å; L219-L221 PolarHBondContact O-N 2.84Å
220	P	43.3	Very low	47.9	Very low	114 Å²	114	117.7 Å²	117.7	74%	0.74	73%	0.733	S	S	*	*			trans	-64.6	113.3	169.1	27.2	-29	0	0	0	106.6	A218 A222	A218-P220 WeakPolarHBondContact O-CD 3.23Å; P220-A222 VanDerWaalsContact C-N 3.34Å; P220-A222 PolarHBondContact O-N 3.45Å
221	L	48.9	Very low	46.2	Very low	159 Å²	159	117.5 Å²	117.5	83%	0.832	74%	0.741	S	S	*	*			trans	-51.9	109.8	153	-73	51.6	0	0	0	104.1	L219 P223	L219-L221 WeakPolarHBondContact O-CD1 3.43Å; L219-L221 PolarHBondContact O-N 2.84Å; L221-P223 WeakPolarHBondContact O-CD 3.31Å
222	A	39.3	Very low	44.5	Very low	91 Å²	91	116.5 Å²	116.5	75%	0.752	75%	0.747	S	S	*	*			trans	-54.7	124.3	-175.3	0	0	0	0	0	109.4	P220 N224	P220-A222 VanDerWaalsContact C-N 3.34Å; P220-A222 PolarHBondContact O-N 3.45Å; A222-N224 PolarHBondContact O-N 3.42Å
223	P	44.1	Very low	43.4	Very low	114 Å²	114	121.8 Å²	121.8	74%	0.74	77%	0.77	S	S	*	*			trans	-73.4	116.3	168.1	17.6	-8.2	0	0	0	107.2	L221 H225	L221-P223 WeakPolarHBondContact O-CD 3.31Å; P223-H225 PolarHBondContact O-N 3.31Å
224	N	46.6	Very low	42.6	Very low	176 Å²	176	114.9 Å²	114.9	94%	0.941	77%	0.766	S	S	*	*			trans	-61.7	98.7	173.8	-157.6	44.5	0	0	0	108.9	A222	A222-N224 PolarHBondContact O-N 3.42Å
225	H	41.1	Very low	42.1	Very low	155 Å²	155	117.1 Å²	117.1	72%	0.718	78%	0.784	S	S	*	*			trans	-141.5	106.1	167.1	117.7	-84	0	0	0	109	P223	P223-H225 PolarHBondContact O-N 3.31Å
226	L	36.7	Very low	41.7	Very low	150 Å²	150	121.3 Å²	121.3	79%	0.785	80%	0.795	S	S	*	*				-162.7	117.9	127.7	-138.3	66.7	0	0	0	108.4
227	G	37.4	Very low	41.1	Very low	83 Å²	83	120.3 Å²	120.3	86%	0.856	79%	0.794	S	S	*	*			trans	-73.5	163.2	-172.2	0	0	0	0	0	114.7
228	G	34.2	Very low	40.4	Very low	84 Å²	84	123.3 Å²	123.3	87%	0.866	79%	0.794	S	S	*	*			trans	169.6	64.9	170.1	0	0	0	0	0	115.5
229	G	37.1	Very low	40.6	Very low	80 Å²	80	125 Å²	125	83%	0.825	81%	0.808	S	S	*	*			trans	83.9	140.1	142.6	0	0	0	0	0	120.7
230	A	36.3	Very low	40.3	Very low	104 Å²	104	123.4 Å²	123.4	86%	0.86	81%	0.809	S	S	*	*			trans	92.8	101.7	157.2	0	0	0	0	0	119.1
231	V	43.6	Very low	40.4	Very low	130 Å²	130	128 Å²	128	79%	0.788	82%	0.817	S	S	*	*			trans	-20.5	125.7	141.9	165.7	0	0	0	0	113.6
232	V	37.1	Very low	39.8	Very low	137 Å²	137	127.4 Å²	127.4	83%	0.83	82%	0.815	S	S	*	*			trans	-148.4	119.2	137.3	174.6	0	0	0	0	108.7
233	L	43.8	Very low	40.2	Very low	168 Å²	168	129 Å²	129	88%	0.88	82%	0.815	S	S	*	*			trans	-68.3	137.8	159.6	-94.6	112	0	0	0	109.7
234	G	39.5	Very low	40.2	Very low	69 Å²	69	127.4 Å²	127.4	71%	0.711	81%	0.811	S	S	*	*			trans	125.2	147.2	140.5	0	0	0	0	0	117.6
235	A	37	Very low	40.1	Very low	109 Å²	109	125.6 Å²	125.6	90%	0.901	80%	0.8	S	S	*	*			trans	90.9	117.1	156.2	0	0	0	0	0	118.1
236	E	37.9	Very low	40.4	Very low	181 Å²	181	122.9 Å²	122.9	85%	0.846	79%	0.791	S	S	*	*			trans	-66.9	169	170	-52.9	-165.8	116.8	0	0	113.1
237	S	39.6	Very low	41.1	Very low	93 Å²	93	121.6 Å²	121.6	65%	0.65	78%	0.782	S	S	*	*			trans	78.8	117.4	158.7	-55.4	0	0	0	0	116.7
238	H	35.3	Very low	41.7	Very low	181 Å²	181	125.1 Å²	125.1	84%	0.838	78%	0.778	S	S	*	*				-178.1	130.7	99.1	-97.3	-78.8	0	0	0	111	S240	H238-S240 PolarHBondContact O-N 2.95Å
239	A	48.6	Very low	42.6	Very low	105 Å²	105	125.7 Å²	125.7	87%	0.868	76%	0.761	S	S	*	*			trans	-52.7	115.8	170.5	0	0	0	0	0	111.1
240	S	38	Very low	43.4	Very low	108 Å²	108	125.4 Å²	125.4	76%	0.755	75%	0.747	S	S	*	*			trans	-124.4	121.1	161.7	-72	0	0	0	0	107.5	H238 D242	H238-S240 PolarHBondContact O-N 2.95Å; S240-D242 PolarHBondContact O-N 3.46Å
241	K	45.5	Very low	44.4	Very low	211 Å²	211	128.9 Å²	128.9	92%	0.917	74%	0.738	S	S	*	*			trans	-54.6	100	169.2	-97.4	171	168.3	169.3	0	108.1	V243	K241-V243 PolarHBondContact O-N 3.3Å
242	D	37.2	Very low	45.2	Very low	147 Å²	147	125.6 Å²	125.6	79%	0.786	72%	0.718	S	S	*	*			trans	-77.9	108.3	171.7	-152.7	16.7	0	0	0	107	S240 A244	S240-D242 PolarHBondContact O-N 3.46Å; D242-A244 PolarHBondContact O-N 2.99Å
243	V	46.8	Very low	46.4	Very low	125 Å²	125	122.1 Å²	122.1	76%	0.758	70%	0.7	S	S	*	*			trans	-73.8	81.7	162.5	-179.1	0	0	0	0	104.6	K241 I245	K241-V243 PolarHBondContact O-N 3.3Å; V243-I245 VanDerWaalsContact C-N 3.28Å; V243-I245 PolarHBondContact O-N 3.2Å
244	A	44.8	Very low	47.3	Very low	79 Å²	79	120.6 Å²	120.6	65%	0.653	69%	0.688	S	S	*	*			trans	-59.9	99.6	169.5	0	0	0	0	0	106.8	D242 D246	D242-A244 PolarHBondContact O-N 2.99Å; A244-D246 PolarHBondContact O-N 3.39Å
245	I	44.9	Very low	48.5	Very low	138 Å²	138	122 Å²	122	71%	0.708	68%	0.676	S	S	*	*			trans	-53.3	112.2	170.9	-78.1	168.5	0	0	0	106.8	V243 M247	V243-I245 VanDerWaalsContact C-N 3.28Å; V243-I245 PolarHBondContact O-N 3.2Å; I245-M247 HydrophobicContact CG2-CB 3.75Å; I245-M247 PolarHBondContact O-N 3.02Å
246	D	48.2	Very low	49.9	Very low	98 Å²	98	122.1 Å²	122.1	52%	0.524	66%	0.661	S	S	.	*			trans	-69.9	56	176.9	-174.4	31.2	0	0	0	111.6	A244 M248 D249	A244-D246 PolarHBondContact O-N 3.39Å; D246-M248 VanDerWaalsContact C-N 3.29Å; D246-D249 WeakPolarHBondContact OD1-CB 3.5Å; D246-D249 PolarHBondContact OD1-N 3.08Å
247	M	50.4	Low	51.3	Low	123 Å²	123	120.2 Å²	120.2	61%	0.606	65%	0.652	S	S	*	*	T	Hydrogen-bonded Turn	trans	-86.2	-7.4	177.8	-165.6	175	-151.2	0	0	111.6	I245	I245-M247 HydrophobicContact CG2-CB 3.75Å; I245-M247 PolarHBondContact O-N 3.02Å
248	M	50.7	Low	52.6	Low	157 Å²	157	120.9 Å²	120.9	77%	0.773	65%	0.648	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.2	-38.9	174.2	-164.3	160.9	-178.6	0	0	111.3	D246 R251 T252	D246-M248 VanDerWaalsContact C-N 3.29Å; M248-R251 PolarHBondContact O-N 2.95Å; M248-T252 WeakPolarHBondContact O-CB 3.42Å; M248-T252 PolarHBondContact O-N 3.15Å; M248-T252 VanDerWaalsContact O-N 3.1Å; M248-T252 PolarHBondContact O-OG1 3.19Å
249	D	51.7	Low	54.1	Low	96 Å²	96	116.1 Å²	116.1	51%	0.513	63%	0.628	S	S	.	*	H	α-helix	trans	-78.5	-31.4	179.8	-147.3	8.8	0	0	0	112.2	D246 R251 T252 S253	D246-D249 WeakPolarHBondContact OD1-CB 3.5Å; D246-D249 PolarHBondContact OD1-N 3.08Å; D249-R251 VanDerWaalsContact C-N 3.34Å; D249-R251 PolarHBondContact O-N 3.1Å; D249-T252 PolarHBondContact O-N 3.26Å; D249-S253 WeakPolarHBondContact O-CB 3.33Å; D249-S253 PolarHBondContact O-N 3.37Å; D249-S253 PolarHBondContact O-OG 2.93Å
250	S	54.5	Low	55	Low	75 Å²	75	116.7 Å²	116.7	52%	0.524	62%	0.616	S	S	.	*	H	α-helix	trans	-66.7	-28.6	171.3	-69.6	0	0	0	0	114	S253	S250-S253 WeakPolarHBondContact CA-OG 3.35Å; S250-S253 PolarHBondContact O-OG 3.35Å
251	R	57.4	Low	56.5	Low	177 Å²	177	118.5 Å²	118.5	67%	0.668	61%	0.613	S	S	*	*	H	α-helix	trans	-83.8	-37.1	175.3	-79.8	-175.3	166.8	-169	-1.8	112.2	M248 D249 Q254 Q255	M248-R251 PolarHBondContact O-N 2.95Å; D249-R251 VanDerWaalsContact C-N 3.34Å; D249-R251 PolarHBondContact O-N 3.1Å; R251-Q254 PolarHBondContact O-N 3.39Å; R251-Q255 PolarHBondContact O-N 2.92Å; R251-Q255 VanDerWaalsContact O-N 3.09Å
252	T	61.4	Low	57.5	Low	61 Å²	61	112.8 Å²	112.8	37%	0.374	59%	0.59	S	S	.	*	H	α-helix	trans	-66.8	-41.9	176.5	-58.8	0	0	0	0	111.6	M248 D249 Q254 Q255 L256	M248-T252 WeakPolarHBondContact O-CB 3.42Å; M248-T252 PolarHBondContact O-N 3.15Å; M248-T252 VanDerWaalsContact O-N 3.1Å; M248-T252 PolarHBondContact O-OG1 3.19Å; D249-T252 PolarHBondContact O-N 3.26Å; T252-Q254 PolarHBondContact O-N 2.82Å; T252-Q255 PolarHBondContact O-N 3.38Å; T252-L256 HydrophobicContact CG2-CD1 3.89Å; T252-L256 WeakPolarHBondContact O-CD1 3.47Å; T252-L256 PolarHBondContact O-N 3.28Å
253	S	61.8	Low	59.3	Low	64 Å²	64	110.3 Å²	110.3	45%	0.448	58%	0.576	S	S	.	*	H	α-helix	trans	-63.4	-39.2	175.6	50.4	0	0	0	0	112.9	D249 S250 Q255 L256 Q257	D249-S253 WeakPolarHBondContact O-CB 3.33Å; D249-S253 PolarHBondContact O-N 3.37Å; D249-S253 PolarHBondContact O-OG 2.93Å; S250-S253 WeakPolarHBondContact CA-OG 3.35Å; S250-S253 PolarHBondContact O-OG 3.35Å; S253-Q255 VanDerWaalsContact C-N 3.32Å; S253-Q255 PolarHBondContact O-N 2.85Å; S253-L256 PolarHBondContact O-N 3.02Å; S253-Q257 PolarHBondContact O-N 2.91Å
254	Q	63.2	Low	60.8	Low	135 Å²	135	108.2 Å²	108.2	63%	0.631	57%	0.567	S	S	*	*	H	α-helix	trans	-69.6	-29.7	175.8	-154.7	170.5	42.4	0	0	112.6	R251 T252	R251-Q254 PolarHBondContact O-N 3.39Å; T252-Q254 PolarHBondContact O-N 2.82Å
255	Q	63.4	Low	62.3	Low	99 Å²	99	109.5 Å²	109.5	46%	0.463	56%	0.556	S	S	.	*	H	α-helix	trans	-75.3	-36.6	173.8	-169.8	173.8	-8.2	0	0	112.4	R251 T252 S253 Q257 L258 I259	R251-Q255 PolarHBondContact O-N 2.92Å; R251-Q255 VanDerWaalsContact O-N 3.09Å; T252-Q255 PolarHBondContact O-N 3.38Å; S253-Q255 VanDerWaalsContact C-N 3.32Å; S253-Q255 PolarHBondContact O-N 2.85Å; Q255-Q257 VanDerWaalsContact C-N 3.33Å; Q255-Q257 PolarHBondContact O-N 3.46Å; Q255-L258 PolarHBondContact O-N 3.03Å; Q255-I259 HydrophobicContact CG-CD1 4.36Å; Q255-I259 WeakPolarHBondContact O-CG1 3.31Å; Q255-I259 PolarHBondContact O-N 3.38Å
256	L	66.4	Low	63.8	Low	112 Å²	112	105.8 Å²	105.8	59%	0.586	54%	0.537	S	S	*	.	H	α-helix	trans	-62.8	-39	173.6	-102.2	90.9	0	0	0	112.1	T252 S253 L258 I259 D260	T252-L256 HydrophobicContact CG2-CD1 3.89Å; T252-L256 WeakPolarHBondContact O-CD1 3.47Å; T252-L256 PolarHBondContact O-N 3.28Å; S253-L256 PolarHBondContact O-N 3.02Å; L256-L258 VanDerWaalsContact C-N 3.31Å; L256-L258 PolarHBondContact O-N 3.43Å; L256-I259 PolarHBondContact O-N 3.25Å; L256-I259 VanDerWaalsContact O-N 3.16Å; L256-D260 PolarHBondContact O-N 3.21Å
257	Q	67.3	Low	65.4	Low	140 Å²	140	106.4 Å²	106.4	65%	0.654	54%	0.537	S	S	*	.	H	α-helix	trans	-66.2	-33.8	-179.6	-157.2	172.3	1.3	0	0	112.5	S253 Q255 I259 E261	S253-Q257 PolarHBondContact O-N 2.91Å; Q255-Q257 VanDerWaalsContact C-N 3.33Å; Q255-Q257 PolarHBondContact O-N 3.46Å; Q257-I259 VanDerWaalsContact C-N 3.34Å; Q257-E261 PolarHBondContact O-N 3.36Å
258	L	66.4	Low	66.8	Low	108 Å²	108	103.5 Å²	103.5	57%	0.565	53%	0.528	S	S	*	.	H	α-helix	trans	-73.5	-24.4	174.6	-70.5	171.1	0	0	0	113.5	Q255 L256 Q262	Q255-L258 PolarHBondContact O-N 3.03Å; L256-L258 VanDerWaalsContact C-N 3.31Å; L256-L258 PolarHBondContact O-N 3.43Å; L258-Q262 PolarHBondContact O-N 3.04Å
259	I	67.8	Low	68.2	Low	80 Å²	80	97.5 Å²	97.5	41%	0.41	50%	0.497	S	S	.	.	H	α-helix	trans	-77.5	-44.4	174.6	-68.8	164.2	0	0	0	109.5	Q255 L256 Q257 E261 Q262 D263	Q255-I259 HydrophobicContact CG-CD1 4.36Å; Q255-I259 WeakPolarHBondContact O-CG1 3.31Å; Q255-I259 PolarHBondContact O-N 3.38Å; L256-I259 PolarHBondContact O-N 3.25Å; L256-I259 VanDerWaalsContact O-N 3.16Å; Q257-I259 VanDerWaalsContact C-N 3.34Å; I259-E261 PolarHBondContact O-N 2.79Å; I259-Q262 WeakPolarHBondContact O-CB 3.42Å; I259-Q262 PolarHBondContact O-N 3.1Å; I259-Q262 VanDerWaalsContact O-N 3.12Å; I259-D263 PolarHBondContact O-N 2.88Å
260	D	67.6	Low	69.7	Low	117 Å²	117	94.3 Å²	94.3	63%	0.626	48%	0.484	S	S	*	.	H	α-helix	trans	-61.6	-41.6	179.2	-166.8	50.9	0	0	0	112.4	L256 Q262 D263 S264	L256-D260 PolarHBondContact O-N 3.21Å; D260-Q262 VanDerWaalsContact C-N 3.31Å; D260-Q262 PolarHBondContact O-N 3.15Å; D260-D263 PolarHBondContact O-N 3.12Å; D260-S264 WeakPolarHBondContact O-CB 3.34Å; D260-S264 PolarHBondContact O-N 3.46Å
261	E	68.9	Low	71.2	Confident	146 Å²	146	93.9 Å²	93.9	68%	0.682	48%	0.476	S	S	*	.	H	α-helix	trans	-66.1	-33.6	175.6	-157.8	-175.9	124.9	0	0	112.3	Q257 I259 Y265	Q257-E261 PolarHBondContact O-N 3.36Å; I259-E261 PolarHBondContact O-N 2.79Å; E261-Y265 PolarHBondContact O-N 3.44Å
262	Q	67.4	Low	72.4	Confident	92 Å²	92	86.2 Å²	86.2	43%	0.43	45%	0.449	S	S	.	.	H	α-helix	trans	-71.1	-43.2	174.9	-101.8	177.9	80.5	0	0	112.5	L258 I259 D260 Y265 I266	L258-Q262 PolarHBondContact O-N 3.04Å; I259-Q262 WeakPolarHBondContact O-CB 3.42Å; I259-Q262 PolarHBondContact O-N 3.1Å; I259-Q262 VanDerWaalsContact O-N 3.12Å; D260-Q262 VanDerWaalsContact C-N 3.31Å; D260-Q262 PolarHBondContact O-N 3.15Å; Q262-Y265 PolarHBondContact O-N 3.04Å; Q262-I266 WeakPolarHBondContact O-CG1 3.48Å; Q262-I266 PolarHBondContact O-N 3.12Å
263	D	73.9	Confident	73.6	Confident	95 Å²	95	86 Å²	86	51%	0.508	44%	0.444	S	S	.	.	H	α-helix	trans	-66.5	-40.3	-179.8	-78.7	-18.8	0	0	0	111.2	I259 D260 Y265 I266 Q267	I259-D263 PolarHBondContact O-N 2.88Å; D260-D263 PolarHBondContact O-N 3.12Å; D263-Y265 VanDerWaalsContact C-N 3.34Å; D263-Y265 PolarHBondContact O-N 2.92Å; D263-I266 PolarHBondContact O-N 3.07Å; D263-Q267 WeakPolarHBondContact O-CB 3.49Å; D263-Q267 PolarHBondContact O-N 3.23Å
264	S	78.6	Confident	74.8	Confident	81 Å²	81	89 Å²	89	57%	0.566	45%	0.451	S	S	*	.	H	α-helix	trans	-52.6	-48.6	171.3	164.7	0	0	0	0	112.5	D260 Q267 S268	D260-S264 WeakPolarHBondContact O-CB 3.34Å; D260-S264 PolarHBondContact O-N 3.46Å; S264-Q267 PolarHBondContact O-N 3.31Å; S264-S268 WeakPolarHBondContact O-CB 3.25Å; S264-S268 PolarHBondContact O-N 3.39Å
265	Y	75.6	Confident	76	Confident	105 Å²	105	86.6 Å²	86.6	41%	0.412	44%	0.443	S	S	.	.	H	α-helix	trans	-65.5	-42.4	178.6	179.5	-94.9	0	0	0	112.3	E261 Q262 D263 Q267 S268 R269	E261-Y265 PolarHBondContact O-N 3.44Å; Q262-Y265 PolarHBondContact O-N 3.04Å; D263-Y265 VanDerWaalsContact C-N 3.34Å; D263-Y265 PolarHBondContact O-N 2.92Å; Y265-Q267 VanDerWaalsContact C-N 3.34Å; Y265-S268 PolarHBondContact O-N 3.29Å; Y265-R269 HydrophobicContact CD1-CG 4.25Å; Y265-R269 HydrophobicContact CE1-CG 3.85Å; Y265-R269 HydrophobicContact CE2-CG 4.38Å; Y265-R269 VanDerWaalsContact CZ-NE 3.32Å; Y265-R269 WeakPolarHBondContact O-CG 3.48Å; Y265-R269 PolarHBondContact O-N 2.99Å; Y265-R269 VanDerWaalsContact OH-CZ 3.3Å; Y265-R269 PolarHBondContact OH-NE 3.03Å; Y265-R269 VanDerWaalsContact OH-NE 3.12Å; Y265-R269 PolarHBondContact OH-NH2 2.88Å
266	I	76.6	Confident	77.2	Confident	61 Å²	61	82.1 Å²	82.1	31%	0.313	42%	0.422	S	S	.	.	H	α-helix	trans	-65.4	-40.2	179.6	-69.5	-172.2	0	0	0	111.2	Q262 D263 R269 A270	Q262-I266 WeakPolarHBondContact O-CG1 3.48Å; Q262-I266 PolarHBondContact O-N 3.12Å; D263-I266 PolarHBondContact O-N 3.07Å; I266-R269 PolarHBondContact O-N 3.45Å; I266-A270 PolarHBondContact O-N 3.24Å
267	Q	81.9	Confident	78.3	Confident	110 Å²	110	81.3 Å²	81.3	51%	0.514	42%	0.415	S	S	.	.	H	α-helix	trans	-63.2	-50	176.5	-170.9	60.4	34.5	0	0	110.6	D263 S264 Y265 R269 A270 D271	D263-Q267 WeakPolarHBondContact O-CB 3.49Å; D263-Q267 PolarHBondContact O-N 3.23Å; S264-Q267 PolarHBondContact O-N 3.31Å; Y265-Q267 VanDerWaalsContact C-N 3.34Å; Q267-R269 VanDerWaalsContact C-N 3.27Å; Q267-R269 PolarHBondContact O-N 2.93Å; Q267-A270 WeakPolarHBondContact O-CB 3.5Å; Q267-A270 PolarHBondContact O-N 3.47Å; Q267-D271 PolarHBondContact NE2-OD1 2.96Å; Q267-D271 VanDerWaalsContact NE2-OD1 3.11Å; Q267-D271 VanDerWaalsContact O-CG 3.24Å; Q267-D271 PolarHBondContact O-N 2.76Å
268	S	81.3	Confident	79.4	Confident	62 Å²	62	77.2 Å²	77.2	43%	0.434	40%	0.402	S	S	.	.	H	α-helix	trans	-54.6	-42	176.3	173.4	0	0	0	0	112.3	S264 Y265 D271 T272	S264-S268 WeakPolarHBondContact O-CB 3.25Å; S264-S268 PolarHBondContact O-N 3.39Å; Y265-S268 PolarHBondContact O-N 3.29Å; S268-D271 PolarHBondContact O-N 2.95Å; S268-T272 PolarHBondContact O-N 3.46Å; S268-T272 PolarHBondContact O-OG1 3.35Å
269	R	79.5	Confident	80.5	Confident	31 Å²	31	72.5 Å²	72.5	12%	0.117	38%	0.378	C	S	.	.	H	α-helix	trans	-70	-34.6	177.3	-66.7	-50.3	-169	143.1	4.5	113.6	D127 L201 Y265 I266 Q267 M273	D127-R269 IonicContact OD2-CZ 2.97Å; D127-R269 VanDerWaalsContact OD2-CZ 3.25Å; D127-R269 IonicContact OD2-NH1 3.87Å; D127-R269 PolarHBondContact OD2-NH1 2.96Å; D127-R269 IonicContact OD2-NH2 2.7Å; D127-R269 PolarHBondContact OD2-NH2 3.5Å; L201-R269 HydrophobicContact CD2-CB 4.21Å; L201-R269 HydrophobicContact CD2-CG 4.23Å; Y265-R269 HydrophobicContact CD1-CG 4.25Å; Y265-R269 HydrophobicContact CE1-CG 3.85Å; Y265-R269 HydrophobicContact CE2-CG 4.38Å; Y265-R269 VanDerWaalsContact CZ-NE 3.32Å; Y265-R269 WeakPolarHBondContact O-CG 3.48Å; Y265-R269 PolarHBondContact O-N 2.99Å; Y265-R269 VanDerWaalsContact OH-CZ 3.3Å; Y265-R269 PolarHBondContact OH-NE 3.03Å; Y265-R269 VanDerWaalsContact OH-NE 3.12Å; Y265-R269 PolarHBondContact OH-NH2 2.88Å; I266-R269 PolarHBondContact O-N 3.45Å; Q267-R269 VanDerWaalsContact C-N 3.27Å; Q267-R269 PolarHBondContact O-N 2.93Å; R269-M273 WeakPolarHBondContact O-CB 3.2Å; R269-M273 PolarHBondContact O-N 2.97Å
270	A	83.1	Confident	81.6	Confident	29 Å²	29	70.2 Å²	70.2	24%	0.24	37%	0.366	C	S	.	.	H	α-helix	trans	-64.6	-44.4	174.3	0	0	0	0	0	110.5	I266 Q267 M273 Q274	I266-A270 PolarHBondContact O-N 3.24Å; Q267-A270 WeakPolarHBondContact O-CB 3.5Å; Q267-A270 PolarHBondContact O-N 3.47Å; A270-M273 PolarHBondContact O-N 3.37Å; A270-Q274 PolarHBondContact O-N 3.38Å
271	D	86.4	Confident	82.7	Confident	66 Å²	66	70 Å²	70	35%	0.353	37%	0.368	S	S	.	.	H	α-helix	trans	-61.9	-45.2	177.2	-60.3	-21.9	0	0	0	111	Q267 S268 M273 Q274 N275	Q267-D271 PolarHBondContact NE2-OD1 2.96Å; Q267-D271 VanDerWaalsContact NE2-OD1 3.11Å; Q267-D271 VanDerWaalsContact O-CG 3.24Å; Q267-D271 PolarHBondContact O-N 2.76Å; S268-D271 PolarHBondContact O-N 2.95Å; D271-M273 VanDerWaalsContact C-N 3.32Å; D271-M273 PolarHBondContact O-N 2.94Å; D271-Q274 PolarHBondContact O-N 2.83Å; D271-N275 VanDerWaalsContact O-CG 3.27Å; D271-N275 PolarHBondContact O-N 3.29Å; D271-N275 PolarHBondContact O-ND2 3.39Å
272	T	82.6	Confident	83.7	Confident	17 Å²	17	66.4 Å²	66.4	10%	0.104	35%	0.352	C	S	.	.	H	α-helix	trans	-59.1	-42.9	174.7	-49.6	0	0	0	0	111.8	S268 N275 I276	S268-T272 PolarHBondContact O-N 3.46Å; S268-T272 PolarHBondContact O-OG1 3.35Å; T272-N275 PolarHBondContact O-N 3.43Å; T272-I276 HydrophobicContact CG2-CD1 4.1Å; T272-I276 VanDerWaalsContact O-CG1 3.3Å; T272-I276 WeakPolarHBondContact O-CG1 3.5Å; T272-I276 PolarHBondContact O-N 2.82Å
273	M	85.3	Confident	84.7	Confident	56 Å²	56	62.3 Å²	62.3	28%	0.276	33%	0.333	S	S	.	.	H	α-helix	trans	-64	-42.4	179.2	-179	166.1	163	0	0	111.4	T198 R269 A270 D271 N275 I276 E277	T198-M273 HydrophobicContact CG2-CE 3.79Å; T198-M273 HydrophobicContact CG2-CG 4.14Å; T198-M273 HydrophobicContact CG2-SD 4.15Å; R269-M273 WeakPolarHBondContact O-CB 3.2Å; R269-M273 PolarHBondContact O-N 2.97Å; A270-M273 PolarHBondContact O-N 3.37Å; D271-M273 VanDerWaalsContact C-N 3.32Å; D271-M273 PolarHBondContact O-N 2.94Å; M273-N275 PolarHBondContact O-N 3.12Å; M273-I276 PolarHBondContact O-N 3.44Å; M273-E277 WeakPolarHBondContact CE-OE1 3.37Å; M273-E277 WeakPolarHBondContact O-CG 3.47Å; M273-E277 PolarHBondContact O-N 3.39Å
274	Q	88	Confident	85.4	Confident	127 Å²	127	59.1 Å²	59.1	59%	0.593	32%	0.322	S	S	*	.	H	α-helix	trans	-62.8	-40.8	175.1	-176.1	176.4	-9	0	0	112.2	A270 D271 I276 E277 S278	A270-Q274 PolarHBondContact O-N 3.38Å; D271-Q274 PolarHBondContact O-N 2.83Å; Q274-I276 VanDerWaalsContact C-N 3.32Å; Q274-I276 PolarHBondContact O-N 2.93Å; Q274-E277 PolarHBondContact O-N 3.42Å; Q274-S278 WeakPolarHBondContact O-CB 3.21Å; Q274-S278 PolarHBondContact O-N 3.18Å
275	N	87.7	Confident	85.9	Confident	84 Å²	84	58.8 Å²	58.8	45%	0.449	32%	0.32	S	S	.	.	H	α-helix	trans	-62.3	-39.9	175.5	-71.6	-17.8	0	0	0	112	D271 T272 M273 T279	D271-N275 VanDerWaalsContact O-CG 3.27Å; D271-N275 PolarHBondContact O-N 3.29Å; D271-N275 PolarHBondContact O-ND2 3.39Å; T272-N275 PolarHBondContact O-N 3.43Å; M273-N275 PolarHBondContact O-N 3.12Å; N275-T279 WeakPolarHBondContact O-CB 3.38Å; N275-T279 PolarHBondContact O-N 3.11Å; N275-T279 PolarHBondContact O-OG1 3.01Å
276	I	88.8	Confident	86.4	Confident	6 Å²	6	54.1 Å²	54.1	3%	0.031	30%	0.302	C	S	.	.	H	α-helix	trans	-65.9	-46.2	175.5	-69.1	169.9	0	0	0	110.6	L194 R197 T198 L201 T272 M273 Q274 S278 T279 I280	L194-I276 HydrophobicContact CB-CG2 3.76Å; L194-I276 HydrophobicContact CD1-CG2 4.33Å; L194-I276 HydrophobicContact CD2-CG1 4.27Å; L194-I276 HydrophobicContact CD2-CG2 4.03Å; L194-I276 HydrophobicContact CG-CG2 4.25Å; R197-I276 HydrophobicContact CB-CD1 4.44Å; R197-I276 HydrophobicContact CG-CD1 3.75Å; T198-I276 WeakPolarHBondContact OG1-CG2 3.4Å; L201-I276 HydrophobicContact CD1-CD1 4.1Å; T272-I276 HydrophobicContact CG2-CD1 4.1Å; T272-I276 VanDerWaalsContact O-CG1 3.3Å; T272-I276 WeakPolarHBondContact O-CG1 3.5Å; T272-I276 PolarHBondContact O-N 2.82Å; M273-I276 PolarHBondContact O-N 3.44Å; Q274-I276 VanDerWaalsContact C-N 3.32Å; Q274-I276 PolarHBondContact O-N 2.93Å; I276-S278 PolarHBondContact O-N 2.84Å; I276-T279 WeakPolarHBondContact O-CB 3.34Å; I276-T279 PolarHBondContact O-N 3.28Å; I276-T279 VanDerWaalsContact O-N 3.13Å; I276-I280 HydrophobicContact CG2-CD1 3.92Å; I276-I280 HydrophobicContact CG2-CG1 4.42Å; I276-I280 WeakPolarHBondContact O-CG1 3.13Å; I276-I280 PolarHBondContact O-N 2.88Å
277	E	89.6	Confident	86.9	Confident	94 Å²	94	53 Å²	53	44%	0.439	30%	0.295	S	S	.	.	H	α-helix	trans	-60.1	-46	177.9	-74.7	179.1	-179.6	0	0	111.9	M273 Q274 T279 I280 V281	M273-E277 WeakPolarHBondContact CE-OE1 3.37Å; M273-E277 WeakPolarHBondContact O-CG 3.47Å; M273-E277 PolarHBondContact O-N 3.39Å; Q274-E277 PolarHBondContact O-N 3.42Å; E277-T279 VanDerWaalsContact C-N 3.28Å; E277-T279 PolarHBondContact O-N 2.78Å; E277-I280 PolarHBondContact O-N 3.44Å; E277-V281 WeakPolarHBondContact O-CG2 3.39Å; E277-V281 PolarHBondContact O-N 3.09Å
278	S	90.7	Very high	87.1	Confident	54 Å²	54	54.8 Å²	54.8	38%	0.378	30%	0.303	S	S	.	.	H	α-helix	trans	-56.9	-42.7	173.4	168.7	0	0	0	0	111.6	Q274 I276 V281 E282	Q274-S278 WeakPolarHBondContact O-CB 3.21Å; Q274-S278 PolarHBondContact O-N 3.18Å; I276-S278 PolarHBondContact O-N 2.84Å; S278-V281 PolarHBondContact O-N 3.47Å; S278-E282 WeakPolarHBondContact O-CG 3.31Å; S278-E282 PolarHBondContact O-N 2.78Å
279	T	90.2	Very high	87.3	Confident	9 Å²	9	56 Å²	56	6%	0.055	30%	0.302	C	S	.	.	H	α-helix	trans	-65.5	-39.7	177.8	-57.9	0	0	0	0	112.1	K140 F190 L194 N275 I276 E277 V281 E282 L283	K140-T279 HydrophobicContact CB-CG2 4.33Å; K140-T279 HydrophobicContact CD-CG2 4.04Å; K140-T279 HydrophobicContact CG-CG2 4.24Å; F190-T279 HydrophobicContact CE1-CG2 3.83Å; F190-T279 HydrophobicContact CZ-CG2 4.12Å; L194-T279 HydrophobicContact CD1-CG2 3.83Å; N275-T279 WeakPolarHBondContact O-CB 3.38Å; N275-T279 PolarHBondContact O-N 3.11Å; N275-T279 PolarHBondContact O-OG1 3.01Å; I276-T279 WeakPolarHBondContact O-CB 3.34Å; I276-T279 PolarHBondContact O-N 3.28Å; I276-T279 VanDerWaalsContact O-N 3.13Å; E277-T279 VanDerWaalsContact C-N 3.28Å; E277-T279 PolarHBondContact O-N 2.78Å; T279-V281 VanDerWaalsContact C-N 3.34Å; T279-V281 PolarHBondContact O-N 3.42Å; T279-E282 PolarHBondContact O-N 3.5Å; T279-L283 HydrophobicContact CG2-CD1 4.37Å; T279-L283 VanDerWaalsContact O-CG 3.27Å; T279-L283 WeakPolarHBondContact O-CG 3.5Å; T279-L283 PolarHBondContact O-N 2.96Å
280	I	90.1	Very high	87.4	Confident	33 Å²	33	54.6 Å²	54.6	17%	0.169	30%	0.297	C	S	.	.	H	α-helix	trans	-62.7	-41.7	175.6	-68.3	168.1	0	0	0	111	K191 L194 E195 I276 E277 L283 G284	K191-I280 HydrophobicContact CD-CG2 4.43Å; K191-I280 HydrophobicContact CG-CG2 4.31Å; L194-I280 HydrophobicContact CB-CD1 4.03Å; L194-I280 HydrophobicContact CB-CG1 4.03Å; L194-I280 HydrophobicContact CD1-CG1 4Å; E195-I280 HydrophobicContact CG-CD1 4.29Å; I276-I280 HydrophobicContact CG2-CD1 3.92Å; I276-I280 HydrophobicContact CG2-CG1 4.42Å; I276-I280 WeakPolarHBondContact O-CG1 3.13Å; I276-I280 PolarHBondContact O-N 2.88Å; E277-I280 PolarHBondContact O-N 3.44Å; I280-L283 PolarHBondContact O-N 3.27Å; I280-G284 PolarHBondContact O-N 3.46Å
281	V	91.3	Very high	87.2	Confident	111 Å²	111	56.1 Å²	56.1	67%	0.673	31%	0.309	S	S	*	.	H	α-helix	trans	-64.6	-44.4	177.4	174.4	0	0	0	0	111.1	E277 S278 T279 L283 G284 S285	E277-V281 WeakPolarHBondContact O-CG2 3.39Å; E277-V281 PolarHBondContact O-N 3.09Å; S278-V281 PolarHBondContact O-N 3.47Å; T279-V281 VanDerWaalsContact C-N 3.34Å; T279-V281 PolarHBondContact O-N 3.42Å; V281-L283 PolarHBondContact O-N 3.1Å; V281-G284 WeakPolarHBondContact O-CA 3.27Å; V281-G284 PolarHBondContact O-N 2.97Å; V281-S285 PolarHBondContact O-N 3.46Å
282	E	88.8	Confident	86.9	Confident	72 Å²	72	59.2 Å²	59.2	34%	0.336	32%	0.322	S	S	.	.	H	α-helix	trans	-61.1	-43	175.7	-74.4	179.1	-146.9	0	0	112.3	K140 S278 T279 G284 S285 I286	K140-E282 WeakPolarHBondContact CE-OE2 3.36Å; K140-E282 IonicContact NZ-OE1 2.86Å; K140-E282 PolarHBondContact NZ-OE1 3.06Å; K140-E282 IonicContact NZ-OE2 2.82Å; K140-E282 PolarHBondContact NZ-OE2 3.37Å; S278-E282 WeakPolarHBondContact O-CG 3.31Å; S278-E282 PolarHBondContact O-N 2.78Å; T279-E282 PolarHBondContact O-N 3.5Å; E282-G284 PolarHBondContact O-N 2.89Å; E282-S285 WeakPolarHBondContact O-CB 2.88Å; E282-S285 PolarHBondContact O-N 2.95Å; E282-I286 PolarHBondContact O-N 2.94Å
283	L	89.5	Confident	86.4	Confident	5 Å²	5	59 Å²	59	3%	0.026	32%	0.319	C	S	.	.	H	α-helix	trans	-59.2	-34.7	173.2	-70.1	167.9	0	0	0	111.4	I143 F190 K191 L194 T279 I280 V281 S285 I286 F287	I143-L283 HydrophobicContact CD1-CD2 4.24Å; I143-L283 HydrophobicContact CG2-CD2 4.14Å; F190-L283 HydrophobicContact CD1-CD1 3.4Å; F190-L283 VanDerWaalsContact CD1-CD1 3.4Å; F190-L283 HydrophobicContact CD1-CD2 3.93Å; F190-L283 HydrophobicContact CD1-CG 4.24Å; F190-L283 HydrophobicContact CE1-CD1 3.77Å; F190-L283 HydrophobicContact CE1-CD2 4.31Å; F190-L283 HydrophobicContact CE1-CG 4.45Å; F190-L283 HydrophobicContact CG-CD1 4.35Å; K191-L283 HydrophobicContact CB-CD1 4.41Å; L194-L283 HydrophobicContact CD1-CD1 4.29Å; T279-L283 HydrophobicContact CG2-CD1 4.37Å; T279-L283 VanDerWaalsContact O-CG 3.27Å; T279-L283 WeakPolarHBondContact O-CG 3.5Å; T279-L283 PolarHBondContact O-N 2.96Å; I280-L283 PolarHBondContact O-N 3.27Å; V281-L283 PolarHBondContact O-N 3.1Å; L283-S285 VanDerWaalsContact C-N 3.27Å; L283-S285 PolarHBondContact O-N 2.89Å; L283-I286 HydrophobicContact CD2-CD1 4.42Å; L283-I286 WeakPolarHBondContact O-CB 3.47Å; L283-I286 PolarHBondContact O-N 3.46Å; L283-I286 VanDerWaalsContact O-N 3.09Å; L283-F287 HydrophobicContact CB-CD2 4.45Å; L283-F287 HydrophobicContact CB-CE2 4.18Å; L283-F287 WeakPolarHBondContact O-CD2 3.49Å; L283-F287 PolarHBondContact O-N 3.32Å
284	G	88.1	Confident	85.6	Confident	28 Å²	28	58.1 Å²	58.1	29%	0.289	32%	0.317	S	S	.	.	H	α-helix	trans	-52.9	-41.8	172.1	0	0	0	0	0	113.3	I280 V281 E282 F287 Q288	I280-G284 PolarHBondContact O-N 3.46Å; V281-G284 WeakPolarHBondContact O-CA 3.27Å; V281-G284 PolarHBondContact O-N 2.97Å; E282-G284 PolarHBondContact O-N 2.89Å; G284-F287 PolarHBondContact O-N 2.81Å; G284-Q288 WeakPolarHBondContact O-CG 3.41Å; G284-Q288 PolarHBondContact O-N 3.29Å; G284-Q288 VanDerWaalsContact O-N 3.1Å
285	S	88	Confident	84.7	Confident	74 Å²	74	60 Å²	60	52%	0.517	32%	0.324	S	S	.	.	H	α-helix	trans	-66.5	-41.8	175.5	-176.4	0	0	0	0	111.8	V281 E282 L283 F287 Q288 Q289	V281-S285 PolarHBondContact O-N 3.46Å; E282-S285 WeakPolarHBondContact O-CB 2.88Å; E282-S285 PolarHBondContact O-N 2.95Å; L283-S285 VanDerWaalsContact C-N 3.27Å; L283-S285 PolarHBondContact O-N 2.89Å; S285-F287 VanDerWaalsContact C-N 3.31Å; S285-F287 PolarHBondContact O-N 3.27Å; S285-Q288 PolarHBondContact O-N 3.44Å; S285-Q289 PolarHBondContact O-N 3.18Å
286	I	87.6	Confident	83.7	Confident	7 Å²	7	60.6 Å²	60.6	4%	0.036	32%	0.323	C	S	.	.	H	α-helix	trans	-62.9	-39.5	176	-59.3	178.5	0	0	0	110.6	I143 N147 E282 L283 Q289 L290	I143-I286 HydrophobicContact CG2-CD1 3.86Å; N147-I286 HydrophobicContact CB-CG2 4.38Å; E282-I286 PolarHBondContact O-N 2.94Å; L283-I286 HydrophobicContact CD2-CD1 4.42Å; L283-I286 WeakPolarHBondContact O-CB 3.47Å; L283-I286 PolarHBondContact O-N 3.46Å; L283-I286 VanDerWaalsContact O-N 3.09Å; I286-Q289 PolarHBondContact O-N 3.03Å; I286-L290 HydrophobicContact CG2-CD1 3.8Å; I286-L290 HydrophobicContact CG2-CG 4.18Å; I286-L290 WeakPolarHBondContact O-CB 3.48Å; I286-L290 VanDerWaalsContact O-CG 3.31Å; I286-L290 WeakPolarHBondContact O-CG 3.29Å; I286-L290 PolarHBondContact O-N 3.45Å
287	F	86.7	Confident	82.3	Confident	37 Å²	37	60.9 Å²	60.9	16%	0.162	33%	0.325	C	S	.	.	H	α-helix	trans	-62.8	-42.5	174.8	-77.4	-62.5	0	0	0	113.1	S187 N188 K191 L283 G284 S285 Q289 L290 A291	S187-F287 WeakPolarHBondContact O-CZ 3.32Å; N188-F287 HydrophobicContact CB-CE1 4.2Å; N188-F287 HydrophobicContact CB-CZ 4.09Å; N188-F287 VanDerWaalsContact CG-CE1 3.43Å; N188-F287 VanDerWaalsContact N-CZ 3.32Å; N188-F287 WeakPolarHBondContact ND2-CE1 3.07Å; N188-F287 WeakPolarHBondContact OD1-CE1 3.11Å; N188-F287 VanDerWaalsContact OD1-CZ 3.25Å; N188-F287 WeakPolarHBondContact OD1-CZ 3.49Å; K191-F287 HydrophobicContact CD-CE2 4.04Å; L283-F287 HydrophobicContact CB-CD2 4.45Å; L283-F287 HydrophobicContact CB-CE2 4.18Å; L283-F287 WeakPolarHBondContact O-CD2 3.49Å; L283-F287 PolarHBondContact O-N 3.32Å; G284-F287 PolarHBondContact O-N 2.81Å; S285-F287 VanDerWaalsContact C-N 3.31Å; S285-F287 PolarHBondContact O-N 3.27Å; F287-Q289 VanDerWaalsContact C-N 3.28Å; F287-Q289 PolarHBondContact O-N 3.1Å; F287-L290 PolarHBondContact O-N 3.25Å; F287-A291 WeakPolarHBondContact O-CB 3.5Å; F287-A291 PolarHBondContact O-N 2.85Å
288	Q	87.1	Confident	80.7	Confident	148 Å²	148	61.7 Å²	61.7	69%	0.692	33%	0.329	S	S	*	.	H	α-helix	trans	-61	-43.2	175.9	-72.8	177.5	-10.8	0	0	110.7	G284 S285 A291 H292	G284-Q288 WeakPolarHBondContact O-CG 3.41Å; G284-Q288 PolarHBondContact O-N 3.29Å; G284-Q288 VanDerWaalsContact O-N 3.1Å; S285-Q288 PolarHBondContact O-N 3.44Å; Q288-A291 PolarHBondContact O-N 3.08Å; Q288-H292 PolarHBondContact O-N 2.83Å
289	Q	84.1	Confident	79	Confident	87 Å²	87	66.4 Å²	66.4	41%	0.407	35%	0.345	S	S	.	.	H	α-helix	trans	-63.6	-47.8	177.2	-167.2	175	15.6	0	0	111.5	N147 S285 I286 F287 A291 H292 M293	N147-Q289 PolarHBondContact ND2-OE1 3.5Å; S285-Q289 PolarHBondContact O-N 3.18Å; I286-Q289 PolarHBondContact O-N 3.03Å; F287-Q289 VanDerWaalsContact C-N 3.28Å; F287-Q289 PolarHBondContact O-N 3.1Å; Q289-A291 PolarHBondContact O-N 3.23Å; Q289-H292 PolarHBondContact O-N 3.09Å; Q289-M293 HydrophobicContact CG-CE 4.17Å; Q289-M293 WeakPolarHBondContact O-CB 3.29Å; Q289-M293 PolarHBondContact O-N 3.17Å
290	L	82.6	Confident	77.4	Confident	3 Å²	3	68.4 Å²	68.4	2%	0.016	36%	0.357	C	S	.	.	H	α-helix	trans	-65.1	-38	177.5	-70.8	173.5	0	0	0	112.1	Q180 L183 A184 I286 F287 M293 V294	Q180-L290 HydrophobicContact CB-CD2 4.31Å; Q180-L290 HydrophobicContact CG-CD2 4.39Å; L183-L290 HydrophobicContact CB-CD1 4.46Å; L183-L290 HydrophobicContact CD2-CD1 4.22Å; L183-L290 HydrophobicContact CD2-CD2 4.17Å; L183-L290 HydrophobicContact CG-CD1 4.09Å; A184-L290 HydrophobicContact CB-CB 4.47Å; A184-L290 HydrophobicContact CB-CD1 3.95Å; I286-L290 HydrophobicContact CG2-CD1 3.8Å; I286-L290 HydrophobicContact CG2-CG 4.18Å; I286-L290 WeakPolarHBondContact O-CB 3.48Å; I286-L290 VanDerWaalsContact O-CG 3.31Å; I286-L290 WeakPolarHBondContact O-CG 3.29Å; I286-L290 PolarHBondContact O-N 3.45Å; F287-L290 PolarHBondContact O-N 3.25Å; L290-M293 HydrophobicContact CD2-SD 4.25Å; L290-M293 PolarHBondContact O-N 2.86Å; L290-V294 WeakPolarHBondContact O-CB 3.33Å; L290-V294 WeakPolarHBondContact O-CG2 3.5Å; L290-V294 PolarHBondContact O-N 2.93Å
291	A	79.2	Confident	75.6	Confident	60 Å²	60	70.1 Å²	70.1	50%	0.496	37%	0.366	S	S	.	.	H	α-helix	trans	-64.8	-44	177.6	0	0	0	0	0	111.5	F287 Q288 Q289 M293 K295	F287-A291 WeakPolarHBondContact O-CB 3.5Å; F287-A291 PolarHBondContact O-N 2.85Å; Q288-A291 PolarHBondContact O-N 3.08Å; Q289-A291 PolarHBondContact O-N 3.23Å; A291-M293 VanDerWaalsContact C-N 3.32Å; A291-K295 WeakPolarHBondContact O-CB 3.15Å; A291-K295 PolarHBondContact O-N 3.24Å
292	H	79.1	Confident	73.7	Confident	132 Å²	132	71.8 Å²	71.8	61%	0.611	37%	0.366	S	S	*	.	H	α-helix	trans	-61.1	-45.5	173	-176.5	-80.5	0	0	0	111	Q288 Q289 V294 K295 E296	Q288-H292 PolarHBondContact O-N 2.83Å; Q289-H292 PolarHBondContact O-N 3.09Å; H292-V294 PolarHBondContact O-N 3.4Å; H292-K295 PolarHBondContact O-N 3.02Å; H292-E296 IonicContact CE1-OE2 2.76Å; H292-E296 PolarHBondContact O-N 2.82Å; H292-E296 VanDerWaalsContact O-N 3.08Å
293	M	72.1	Confident	72	Confident	11 Å²	11	74.1 Å²	74.1	5%	0.054	37%	0.372	C	S	.	.	H	α-helix	trans	-66.5	-35.3	-176	-167.7	-177.7	-78.3	0	0	113.5	I150 A151 Q154 Q180 Q289 L290 A291 Q297	I150-M293 HydrophobicContact CG2-SD 4.26Å; A151-M293 HydrophobicContact CB-CE 4.43Å; Q154-M293 PolarHBondContact OE1-SD 2.77Å; Q154-M293 VanDerWaalsContact OE1-SD 3.35Å; Q180-M293 HydrophobicContact CG-CG 4.26Å; Q180-M293 HydrophobicContact CG-SD 3.63Å; Q180-M293 PolarHBondContact NE2-SD 3.01Å; Q289-M293 HydrophobicContact CG-CE 4.17Å; Q289-M293 WeakPolarHBondContact O-CB 3.29Å; Q289-M293 PolarHBondContact O-N 3.17Å; L290-M293 HydrophobicContact CD2-SD 4.25Å; L290-M293 PolarHBondContact O-N 2.86Å; A291-M293 VanDerWaalsContact C-N 3.32Å; M293-Q297 PolarHBondContact O-NE2 3Å
294	V	69.1	Low	70.2	Confident	39 Å²	39	78 Å²	78	24%	0.236	39%	0.392	C	S	.	.	H	α-helix	trans	-79.3	-42.7	175.8	171.9	0	0	0	0	110.8	Q180 L290 H292 E296 Q297 E298	Q180-V294 HydrophobicContact CB-CG2 4.04Å; L290-V294 WeakPolarHBondContact O-CB 3.33Å; L290-V294 WeakPolarHBondContact O-CG2 3.5Å; L290-V294 PolarHBondContact O-N 2.93Å; H292-V294 PolarHBondContact O-N 3.4Å; V294-E296 VanDerWaalsContact C-N 3.32Å; V294-E296 PolarHBondContact O-N 3.3Å; V294-Q297 CarbonylContact O-C 3.52Å; V294-Q297 PolarHBondContact O-N 3.09Å; V294-E298 PolarHBondContact O-N 3.11Å
295	K	69.1	Low	68.5	Low	166 Å²	166	82.7 Å²	82.7	72%	0.722	41%	0.41	S	S	*	.	H	α-helix	trans	-61.4	-37.9	179.3	-176	178.7	179.6	-178.3	0	112.7	A291 H292 Q297	A291-K295 WeakPolarHBondContact O-CB 3.15Å; A291-K295 PolarHBondContact O-N 3.24Å; H292-K295 PolarHBondContact O-N 3.02Å; K295-Q297 PolarHBondContact O-N 3.34Å
296	E	66.4	Low	66.9	Low	96 Å²	96	84.3 Å²	84.3	45%	0.449	41%	0.41	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.6	-21.5	176.2	-160.5	-172.4	154.9	0	0	112.5	R158 H292 V294	R158-E296 IonicContact CZ-OE1 3.01Å; R158-E296 VanDerWaalsContact CZ-OE1 3.28Å; R158-E296 IonicContact CZ-OE2 2.81Å; R158-E296 IonicContact NH1-OE1 2.82Å; R158-E296 PolarHBondContact NH1-OE1 3.47Å; R158-E296 IonicContact NH2-OE1 3.25Å; R158-E296 PolarHBondContact NH2-OE1 2.98Å; R158-E296 IonicContact NH2-OE2 3.61Å; R158-E296 PolarHBondContact NH2-OE2 3.25Å; H292-E296 IonicContact CE1-OE2 2.76Å; H292-E296 PolarHBondContact O-N 2.82Å; H292-E296 VanDerWaalsContact O-N 3.08Å; V294-E296 VanDerWaalsContact C-N 3.32Å; V294-E296 PolarHBondContact O-N 3.3Å
297	Q	59.1	Low	65.5	Low	13 Å²	13	87.8 Å²	87.8	6%	0.061	43%	0.428	C	S	.	.	T	Hydrogen-bonded Turn	trans	-111.3	-12.3	-174.5	-66.6	179.3	77.1	0	0	114.3	V177 M293 V294 K295 E299 T300	V177-Q297 HydrophobicContact CG2-CB 3.44Å; V177-Q297 VanDerWaalsContact CG2-CB 3.44Å; V177-Q297 HydrophobicContact CG2-CG 4.07Å; M293-Q297 PolarHBondContact O-NE2 3Å; V294-Q297 CarbonylContact O-C 3.52Å; V294-Q297 PolarHBondContact O-N 3.09Å; K295-Q297 PolarHBondContact O-N 3.34Å; Q297-E299 PolarHBondContact O-N 3.36Å; Q297-T300 PolarHBondContact O-N 3.29Å; Q297-T300 PolarHBondContact O-OG1 3.27Å
298	E	56.8	Low	64.2	Low	111 Å²	111	90.3 Å²	90.3	52%	0.519	45%	0.447	S	S	.	.	H	α-helix	trans	-57.3	-32.6	-179.9	-168.4	174.4	175.9	0	0	112.6	V294 T300 I301	V294-E298 PolarHBondContact O-N 3.11Å; E298-T300 PolarHBondContact O-N 2.69Å; E298-I301 PolarHBondContact O-N 2.94Å
299	E	54.7	Low	62.9	Low	152 Å²	152	88.1 Å²	88.1	71%	0.71	44%	0.439	S	S	*	.	H	α-helix	trans	-64.3	-25.2	175.4	-160.5	-177.5	165.4	0	0	112.8	Q297	Q297-E299 PolarHBondContact O-N 3.36Å
300	T	55.7	Low	62.1	Low	52 Å²	52	85.3 Å²	85.3	32%	0.319	43%	0.433	S	S	.	.	H	α-helix	trans	-85.1	-21.4	179	61.8	0	0	0	0	114.1	Q297 E298 R303	Q297-T300 PolarHBondContact O-N 3.29Å; Q297-T300 PolarHBondContact O-OG1 3.27Å; E298-T300 PolarHBondContact O-N 2.69Å; T300-R303 WeakPolarHBondContact O-CB 3.49Å; T300-R303 PolarHBondContact O-N 3.46Å
301	I	52.2	Low	61.5	Low	69 Å²	69	87.7 Å²	87.7	35%	0.354	45%	0.453	S	S	.	.	H	α-helix	trans	-78	-32	178.9	-72.1	-178.8	0	0	0	112	V177 E298 R303 I304	V177-I301 HydrophobicContact CB-CD1 3.78Å; V177-I301 HydrophobicContact CG1-CD1 3.29Å; V177-I301 HydrophobicContact CG1-CG1 4.45Å; V177-I301 HydrophobicContact CG2-CD1 4.28Å; E298-I301 PolarHBondContact O-N 2.94Å; I301-R303 PolarHBondContact O-N 3.21Å; I301-I304 PolarHBondContact O-N 2.91Å
302	Q	51.2	Low	61.2	Low	145 Å²	145	90.5 Å²	90.5	68%	0.678	46%	0.456	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.5	-15.4	173.2	-67.9	-179.3	3.4	0	0	112.7
303	R	53.3	Low	61	Low	121 Å²	121	89.5 Å²	89.5	46%	0.457	46%	0.455	S	S	.	.	H	α-helix	trans	-86.1	3.8	178.4	-62	-161.3	151.8	144.8	7.7	115.7	T300 I301 D305 E306 N307	T300-R303 WeakPolarHBondContact O-CB 3.49Å; T300-R303 PolarHBondContact O-N 3.46Å; I301-R303 PolarHBondContact O-N 3.21Å; R303-D305 PolarHBondContact O-N 3.39Å; R303-E306 HydrophobicContact CB-CB 4.23Å; R303-E306 VanDerWaalsContact CD-OE2 3.29Å; R303-E306 WeakPolarHBondContact CD-OE2 3.36Å; R303-E306 VanDerWaalsContact CG-OE2 3.25Å; R303-E306 WeakPolarHBondContact CG-OE2 3.45Å; R303-E306 IonicContact CZ-OE2 2.7Å; R303-E306 IonicContact NE-OE2 3.86Å; R303-E306 PolarHBondContact NE-OE2 3.21Å; R303-E306 PolarHBondContact O-N 3.49Å; R303-N307 WeakPolarHBondContact O-CB 3.21Å; R303-N307 PolarHBondContact O-N 3.13Å; R303-N307 PolarHBondContact O-ND2 2.95Å
304	I	52.2	Low	61.5	Low	86 Å²	86	94.6 Å²	94.6	44%	0.441	48%	0.483	S	S	.	.	H	α-helix	trans	-62.2	-39.9	171.8	-64.7	175.4	0	0	0	109.5	I301 N307 V308	I301-I304 PolarHBondContact O-N 2.91Å; I304-N307 PolarHBondContact O-N 3.27Å; I304-V308 WeakPolarHBondContact O-CG2 3.45Å; I304-V308 PolarHBondContact O-N 3.43Å; I304-V308 VanDerWaalsContact O-N 3.13Å
305	D	52	Low	62.1	Low	127 Å²	127	97.7 Å²	97.7	68%	0.679	50%	0.501	S	S	*	.	H	α-helix	trans	-66	-40.4	172.6	-79.7	-6.1	0	0	0	112.2	R303 N307 V308 L309	R303-D305 PolarHBondContact O-N 3.39Å; D305-N307 PolarHBondContact O-N 3.47Å; D305-V308 PolarHBondContact O-N 3Å; D305-L309 WeakPolarHBondContact O-CG 3.36Å; D305-L309 PolarHBondContact O-N 3.48Å
306	E	55.4	Low	62.6	Low	108 Å²	108	95.3 Å²	95.3	51%	0.505	49%	0.493	S	S	.	.	H	α-helix	trans	-65	-35.7	176.3	-75.9	-170.7	155.6	0	0	113.2	R303 L309 G310	R303-E306 HydrophobicContact CB-CB 4.23Å; R303-E306 VanDerWaalsContact CD-OE2 3.29Å; R303-E306 WeakPolarHBondContact CD-OE2 3.36Å; R303-E306 VanDerWaalsContact CG-OE2 3.25Å; R303-E306 WeakPolarHBondContact CG-OE2 3.45Å; R303-E306 IonicContact CZ-OE2 2.7Å; R303-E306 IonicContact NE-OE2 3.86Å; R303-E306 PolarHBondContact NE-OE2 3.21Å; R303-E306 PolarHBondContact O-N 3.49Å; E306-L309 PolarHBondContact O-N 2.87Å; E306-G310 PolarHBondContact O-N 3.45Å
307	N	57.4	Low	63.4	Low	80 Å²	80	93.3 Å²	93.3	43%	0.428	49%	0.493	S	S	.	.	H	α-helix	trans	-76	-29.8	178.7	-71.6	-35.2	0	0	0	112.4	R303 I304 D305 G310 A311	R303-N307 WeakPolarHBondContact O-CB 3.21Å; R303-N307 PolarHBondContact O-N 3.13Å; R303-N307 PolarHBondContact O-ND2 2.95Å; I304-N307 PolarHBondContact O-N 3.27Å; D305-N307 PolarHBondContact O-N 3.47Å; N307-G310 PolarHBondContact O-N 3.29Å; N307-A311 WeakPolarHBondContact O-CB 3.47Å; N307-A311 PolarHBondContact O-N 2.83Å
308	V	60.5	Low	64.4	Low	90 Å²	90	95.1 Å²	95.1	55%	0.545	51%	0.51	S	S	.	.	H	α-helix	trans	-66.6	-42.8	170.1	172.1	0	0	0	0	110	I304 D305 A311 Q312	I304-V308 WeakPolarHBondContact O-CG2 3.45Å; I304-V308 PolarHBondContact O-N 3.43Å; I304-V308 VanDerWaalsContact O-N 3.13Å; D305-V308 PolarHBondContact O-N 3Å; V308-A311 PolarHBondContact O-N 2.96Å; V308-Q312 WeakPolarHBondContact O-CB 3.5Å; V308-Q312 PolarHBondContact O-N 2.84Å
309	L	59.7	Low	65.4	Low	102 Å²	102	95.1 Å²	95.1	53%	0.534	51%	0.51	S	S	.	.	H	α-helix	trans	-62.5	-42.9	173.2	-73.1	169.1	0	0	0	112	D305 E306 Q312 L313	D305-L309 WeakPolarHBondContact O-CG 3.36Å; D305-L309 PolarHBondContact O-N 3.48Å; E306-L309 PolarHBondContact O-N 2.87Å; L309-Q312 WeakPolarHBondContact O-CB 3.39Å; L309-Q312 PolarHBondContact O-N 3.45Å; L309-L313 WeakPolarHBondContact O-CG 3.43Å; L309-L313 PolarHBondContact O-N 2.87Å
310	G	66.8	Low	66.4	Low	28 Å²	28	90.5 Å²	90.5	29%	0.289	49%	0.494	S	S	.	.	H	α-helix	trans	-61.5	-44.8	175.4	0	0	0	0	0	112.7	E306 N307 Q312 L313 D314	E306-G310 PolarHBondContact O-N 3.45Å; N307-G310 PolarHBondContact O-N 3.29Å; G310-Q312 VanDerWaalsContact C-N 3.32Å; G310-Q312 PolarHBondContact O-N 3.05Å; G310-L313 PolarHBondContact O-N 3.38Å; G310-D314 PolarHBondContact O-N 3.36Å
311	A	69.7	Low	67.6	Low	53 Å²	53	93.2 Å²	93.2	44%	0.438	50%	0.503	S	S	.	.	H	α-helix	trans	-64	-36.6	175.9	0	0	0	0	0	112.4	N307 V308 D314 V315	N307-A311 WeakPolarHBondContact O-CB 3.47Å; N307-A311 PolarHBondContact O-N 2.83Å; V308-A311 PolarHBondContact O-N 2.96Å; A311-D314 PolarHBondContact O-N 3.27Å; A311-V315 WeakPolarHBondContact O-CB 3.28Å; A311-V315 WeakPolarHBondContact O-CG2 3.48Å; A311-V315 PolarHBondContact O-N 3.44Å
312	Q	72.4	Confident	69	Low	119 Å²	119	95.2 Å²	95.2	56%	0.556	51%	0.513	S	S	*	.	H	α-helix	trans	-63.5	-44.4	174.4	-178.7	177.5	-23.7	0	0	111.7	V308 L309 G310 V315 E316	V308-Q312 WeakPolarHBondContact O-CB 3.5Å; V308-Q312 PolarHBondContact O-N 2.84Å; L309-Q312 WeakPolarHBondContact O-CB 3.39Å; L309-Q312 PolarHBondContact O-N 3.45Å; G310-Q312 VanDerWaalsContact C-N 3.32Å; G310-Q312 PolarHBondContact O-N 3.05Å; Q312-V315 PolarHBondContact O-N 3.31Å; Q312-E316 WeakPolarHBondContact O-CB 3.29Å; Q312-E316 PolarHBondContact O-N 3.33Å
313	L	75.4	Confident	70.2	Confident	111 Å²	111	92.8 Å²	92.8	58%	0.581	51%	0.505	S	S	*	.	H	α-helix	trans	-64.1	-40.8	176.9	-70	171.4	0	0	0	112.2	L309 G310 V315 E316 A317	L309-L313 WeakPolarHBondContact O-CG 3.43Å; L309-L313 PolarHBondContact O-N 2.87Å; G310-L313 PolarHBondContact O-N 3.38Å; L313-V315 VanDerWaalsContact C-N 3.34Å; L313-V315 PolarHBondContact O-N 3Å; L313-E316 PolarHBondContact O-N 3.34Å; L313-A317 WeakPolarHBondContact O-CB 3.25Å; L313-A317 PolarHBondContact O-N 2.89Å
314	D	81.9	Confident	71.3	Confident	119 Å²	119	92.6 Å²	92.6	64%	0.636	51%	0.507	S	S	*	.	H	α-helix	trans	-65	-38.1	176.3	-72.2	-22.3	0	0	0	111.8	G310 A311 A318	G310-D314 PolarHBondContact O-N 3.36Å; A311-D314 PolarHBondContact O-N 3.27Å; D314-A318 WeakPolarHBondContact O-CB 3.41Å; D314-A318 PolarHBondContact O-N 3.48Å
315	V	82.7	Confident	72.3	Confident	103 Å²	103	96.4 Å²	96.4	62%	0.624	52%	0.517	S	S	*	.	H	α-helix	trans	-66.8	-40.5	175	168.4	0	0	0	0	111.3	A311 Q312 L313 A318 H319	A311-V315 WeakPolarHBondContact O-CB 3.28Å; A311-V315 WeakPolarHBondContact O-CG2 3.48Å; A311-V315 PolarHBondContact O-N 3.44Å; Q312-V315 PolarHBondContact O-N 3.31Å; L313-V315 VanDerWaalsContact C-N 3.34Å; L313-V315 PolarHBondContact O-N 3Å; V315-A318 PolarHBondContact O-N 3.37Å; V315-H319 WeakPolarHBondContact O-CB 3.37Å; V315-H319 PolarHBondContact O-N 2.74Å
316	E	79.9	Confident	73.4	Confident	116 Å²	116	97.1 Å²	97.1	54%	0.542	51%	0.514	S	S	.	.	H	α-helix	trans	-68.3	-38.8	177.8	-167.5	167.3	-165.1	0	0	111.9	Q312 L313 H319 S320	Q312-E316 WeakPolarHBondContact O-CB 3.29Å; Q312-E316 PolarHBondContact O-N 3.33Å; L313-E316 PolarHBondContact O-N 3.34Å; E316-H319 PolarHBondContact O-N 2.97Å; E316-S320 WeakPolarHBondContact O-CB 3.41Å; E316-S320 PolarHBondContact O-N 3.46Å; E316-S320 PolarHBondContact O-OG 3.37Å
317	A	81.8	Confident	74	Confident	55 Å²	55	98.8 Å²	98.8	46%	0.455	52%	0.522	S	S	.	.	H	α-helix	trans	-63.3	-44.3	171.8	0	0	0	0	0	111.8	L313 H319 S320 E321	L313-A317 WeakPolarHBondContact O-CB 3.25Å; L313-A317 PolarHBondContact O-N 2.89Å; A317-H319 PolarHBondContact O-N 3.32Å; A317-S320 WeakPolarHBondContact O-CB 3.47Å; A317-S320 PolarHBondContact O-N 2.95Å; A317-E321 PolarHBondContact O-N 3.5Å
318	A	80.9	Confident	74.6	Confident	51 Å²	51	98.1 Å²	98.1	42%	0.421	52%	0.524	S	S	.	.	H	α-helix	trans	-62.6	-40.8	175.4	0	0	0	0	0	112.2	D314 V315 S320 E321 I322	D314-A318 WeakPolarHBondContact O-CB 3.41Å; D314-A318 PolarHBondContact O-N 3.48Å; V315-A318 PolarHBondContact O-N 3.37Å; A318-S320 VanDerWaalsContact C-N 3.31Å; A318-S320 PolarHBondContact O-N 2.95Å; A318-E321 PolarHBondContact O-N 2.91Å; A318-I322 VanDerWaalsContact O-CG1 3.28Å; A318-I322 WeakPolarHBondContact O-CG1 3.39Å; A318-I322 PolarHBondContact O-N 3.31Å
319	H	76.7	Confident	74.8	Confident	111 Å²	111	97.4 Å²	97.4	51%	0.514	52%	0.52	S	S	.	.	H	α-helix	trans	-62.5	-40.2	175.6	-171.8	-97	0	0	0	111.7	V315 E316 A317 I322 L323	V315-H319 WeakPolarHBondContact O-CB 3.37Å; V315-H319 PolarHBondContact O-N 2.74Å; E316-H319 PolarHBondContact O-N 2.97Å; A317-H319 PolarHBondContact O-N 3.32Å; H319-I322 PolarHBondContact O-N 3Å; H319-L323 WeakPolarHBondContact O-CG 3.37Å; H319-L323 PolarHBondContact O-N 3.4Å
320	S	76	Confident	74.8	Confident	54 Å²	54	95.4 Å²	95.4	38%	0.378	51%	0.511	S	S	.	.	H	α-helix	trans	-62.1	-43.7	176.4	-55.6	0	0	0	0	112.2	E316 A317 A318 L323 K324	E316-S320 WeakPolarHBondContact O-CB 3.41Å; E316-S320 PolarHBondContact O-N 3.46Å; E316-S320 PolarHBondContact O-OG 3.37Å; A317-S320 WeakPolarHBondContact O-CB 3.47Å; A317-S320 PolarHBondContact O-N 2.95Å; A318-S320 VanDerWaalsContact C-N 3.31Å; A318-S320 PolarHBondContact O-N 2.95Å; S320-L323 PolarHBondContact O-N 2.69Å; S320-K324 WeakPolarHBondContact O-CG 3.36Å; S320-K324 PolarHBondContact O-N 3.37Å
321	E	80.7	Confident	74.5	Confident	109 Å²	109	98 Å²	98	51%	0.509	53%	0.526	S	S	.	.	H	α-helix	trans	-67.5	-37.8	176.2	-72.1	-58.1	141.7	0	0	112.4	A317 A318 L323 K324 Y325	A317-E321 PolarHBondContact O-N 3.5Å; A318-E321 PolarHBondContact O-N 2.91Å; E321-L323 PolarHBondContact O-N 3.15Å; E321-K324 PolarHBondContact O-N 3.27Å; E321-K324 IonicContact OE1-NZ 2.95Å; E321-K324 PolarHBondContact OE1-NZ 2.99Å; E321-Y325 PolarHBondContact O-N 3.39Å
322	I	82.2	Confident	74.5	Confident	111 Å²	111	100.2 Å²	100.2	57%	0.569	53%	0.53	S	S	*	.	H	α-helix	trans	-62.8	-43	174.3	-69.2	164.5	0	0	0	110.8	A318 H319 Y325 F326	A318-I322 VanDerWaalsContact O-CG1 3.28Å; A318-I322 WeakPolarHBondContact O-CG1 3.39Å; A318-I322 PolarHBondContact O-N 3.31Å; H319-I322 PolarHBondContact O-N 3Å; I322-Y325 PolarHBondContact O-N 2.96Å; I322-F326 WeakPolarHBondContact O-CB 3.39Å; I322-F326 PolarHBondContact O-N 3.48Å
323	L	77.3	Confident	74.5	Confident	95 Å²	95	103.4 Å²	103.4	50%	0.497	54%	0.537	S	S	.	.	H	α-helix	trans	-64.4	-41.6	176.7	-73.6	178.2	0	0	0	112.2	H319 S320 E321 Y325 F326 Q327	H319-L323 WeakPolarHBondContact O-CG 3.37Å; H319-L323 PolarHBondContact O-N 3.4Å; S320-L323 PolarHBondContact O-N 2.69Å; E321-L323 PolarHBondContact O-N 3.15Å; L323-Y325 VanDerWaalsContact C-N 3.34Å; L323-Y325 PolarHBondContact O-N 3.35Å; L323-F326 PolarHBondContact O-N 2.95Å; L323-Q327 WeakPolarHBondContact O-CB 3.39Å; L323-Q327 PolarHBondContact O-N 3.4Å
324	K	76.1	Confident	74.4	Confident	117 Å²	117	107.1 Å²	107.1	51%	0.509	54%	0.543	S	S	.	.	H	α-helix	trans	-59	-45.4	173.3	-73.1	175.8	-168.3	168.5	0	111.4	S320 E321 Q327 S328	S320-K324 WeakPolarHBondContact O-CG 3.36Å; S320-K324 PolarHBondContact O-N 3.37Å; E321-K324 PolarHBondContact O-N 3.27Å; E321-K324 IonicContact OE1-NZ 2.95Å; E321-K324 PolarHBondContact OE1-NZ 2.99Å; K324-Q327 PolarHBondContact O-N 2.95Å; K324-S328 PolarHBondContact O-N 3.48Å
325	Y	73.1	Confident	74.3	Confident	166 Å²	166	106.2 Å²	106.2	65%	0.651	54%	0.538	S	S	*	.	H	α-helix	trans	-62.3	-45	176.2	-175.9	-102.4	0	0	0	111.4	E321 I322 L323 Q327 S328 V329	E321-Y325 PolarHBondContact O-N 3.39Å; I322-Y325 PolarHBondContact O-N 2.96Å; L323-Y325 VanDerWaalsContact C-N 3.34Å; L323-Y325 PolarHBondContact O-N 3.35Å; Y325-Q327 VanDerWaalsContact C-N 3.32Å; Y325-Q327 PolarHBondContact O-N 3.02Å; Y325-S328 PolarHBondContact O-N 3.5Å; Y325-S328 VanDerWaalsContact O-N 3.15Å; Y325-S328 PolarHBondContact O-OG 3.25Å; Y325-V329 HydrophobicContact CD1-CG2 4.12Å; Y325-V329 HydrophobicContact CE1-CG2 3.71Å; Y325-V329 HydrophobicContact CE2-CG2 4.23Å; Y325-V329 WeakPolarHBondContact O-CG2 3.43Å; Y325-V329 PolarHBondContact O-N 3.01Å
326	F	74.6	Confident	74.1	Confident	141 Å²	141	107.5 Å²	107.5	62%	0.618	54%	0.538	S	S	*	.	H	α-helix	trans	-61.4	-40	178.9	-155.3	-90.7	0	0	0	112.4	I322 L323 V329 T330	I322-F326 WeakPolarHBondContact O-CB 3.39Å; I322-F326 PolarHBondContact O-N 3.48Å; L323-F326 PolarHBondContact O-N 2.95Å; F326-V329 PolarHBondContact O-N 3.18Å; F326-T330 WeakPolarHBondContact O-CB 3.45Å; F326-T330 PolarHBondContact O-N 3.33Å
327	Q	68	Low	74.3	Confident	143 Å²	143	106 Å²	106	67%	0.668	54%	0.537	S	S	*	.	H	α-helix	trans	-66.1	-40.6	175.1	-168.4	179.7	6.2	0	0	111.8	L323 K324 Y325 V329 T330 S331	L323-Q327 WeakPolarHBondContact O-CB 3.39Å; L323-Q327 PolarHBondContact O-N 3.4Å; K324-Q327 PolarHBondContact O-N 2.95Å; Y325-Q327 VanDerWaalsContact C-N 3.32Å; Y325-Q327 PolarHBondContact O-N 3.02Å; Q327-V329 VanDerWaalsContact C-N 3.34Å; Q327-V329 PolarHBondContact O-N 3.16Å; Q327-T330 PolarHBondContact O-N 2.95Å; Q327-S331 PolarHBondContact O-N 3.45Å
328	S	70.3	Confident	74.5	Confident	66 Å²	66	109.2 Å²	109.2	46%	0.462	54%	0.541	S	S	.	.	H	α-helix	trans	-63.3	-38.6	175.6	77.4	0	0	0	0	112.4	K324 Y325 S331	K324-S328 PolarHBondContact O-N 3.48Å; Y325-S328 PolarHBondContact O-N 3.5Å; Y325-S328 VanDerWaalsContact O-N 3.15Å; Y325-S328 PolarHBondContact O-OG 3.25Å; S328-S331 PolarHBondContact O-N 3.06Å
329	V	63.8	Low	74.8	Confident	76 Å²	76	111.3 Å²	111.3	46%	0.461	54%	0.544	S	S	.	.	H	α-helix	trans	-71.3	-36.7	176.7	174.7	0	0	0	0	111.5	Y325 F326 Q327 S331	Y325-V329 HydrophobicContact CD1-CG2 4.12Å; Y325-V329 HydrophobicContact CE1-CG2 3.71Å; Y325-V329 HydrophobicContact CE2-CG2 4.23Å; Y325-V329 WeakPolarHBondContact O-CG2 3.43Å; Y325-V329 PolarHBondContact O-N 3.01Å; F326-V329 PolarHBondContact O-N 3.18Å; Q327-V329 VanDerWaalsContact C-N 3.34Å; Q327-V329 PolarHBondContact O-N 3.16Å; V329-S331 VanDerWaalsContact C-N 3.35Å
330	T	59.8	Low	75.4	Confident	59 Å²	59	111.9 Å²	111.9	36%	0.362	55%	0.545	S	S	.	.	H	α-helix	trans	-68.4	-29.6	175.3	-97.2	0	0	0	0	113.3	F326 Q327 N332 R333	F326-T330 WeakPolarHBondContact O-CB 3.45Å; F326-T330 PolarHBondContact O-N 3.33Å; Q327-T330 PolarHBondContact O-N 2.95Å; T330-N332 PolarHBondContact O-N 2.92Å; T330-N332 VanDerWaalsContact O-N 3.16Å; T330-R333 WeakPolarHBondContact O-CG 3.45Å; T330-R333 PolarHBondContact O-N 2.76Å
331	S	61	Low	76.1	Confident	84 Å²	84	114.2 Å²	114.2	59%	0.587	55%	0.553	S	S	*	*	H	α-helix	trans	-60.4	-25.9	-179.9	-168.4	0	0	0	0	113.3	Q327 S328 V329 R333 W334	Q327-S331 PolarHBondContact O-N 3.45Å; S328-S331 PolarHBondContact O-N 3.06Å; V329-S331 VanDerWaalsContact C-N 3.35Å; S331-R333 PolarHBondContact O-N 3.46Å; S331-W334 PolarHBondContact O-N 3.21Å
332	N	68.8	Low	76.5	Confident	98 Å²	98	114.7 Å²	114.7	52%	0.524	56%	0.558	S	S	.	*	H	α-helix	trans	-64.4	-8.9	177.9	-77.8	-22.5	0	0	0	114.6	T330 W334 L335 M336	T330-N332 PolarHBondContact O-N 2.92Å; T330-N332 VanDerWaalsContact O-N 3.16Å; N332-W334 VanDerWaalsContact C-N 3.27Å; N332-W334 PolarHBondContact O-N 2.88Å; N332-L335 WeakPolarHBondContact O-CB 3.27Å; N332-L335 PolarHBondContact O-N 3.46Å; N332-L335 VanDerWaalsContact O-N 3.15Å; N332-M336 PolarHBondContact O-N 3.26Å
333	R	72.7	Confident	76.9	Confident	186 Å²	186	114.4 Å²	114.4	70%	0.702	56%	0.557	S	S	*	*	H	α-helix	trans	-60.4	-37.1	172.5	-71.4	-176.1	177.1	171.4	1	112.4	T330 S331 L335 M336 V337	T330-R333 WeakPolarHBondContact O-CG 3.45Å; T330-R333 PolarHBondContact O-N 2.76Å; S331-R333 PolarHBondContact O-N 3.46Å; R333-L335 VanDerWaalsContact C-N 3.31Å; R333-L335 PolarHBondContact O-N 3.45Å; R333-M336 PolarHBondContact O-N 3.06Å; R333-V337 WeakPolarHBondContact O-CG2 3.45Å; R333-V337 PolarHBondContact O-N 3.3Å
334	W	74.8	Confident	77.4	Confident	190 Å²	190	113.4 Å²	113.4	72%	0.72	55%	0.551	S	S	*	*	H	α-helix	trans	-68.5	-31.6	176.3	-113.4	92.2	0	0	0	112.4	S331 N332 K338	S331-W334 PolarHBondContact O-N 3.21Å; N332-W334 VanDerWaalsContact C-N 3.27Å; N332-W334 PolarHBondContact O-N 2.88Å; W334-K338 HydrophobicContact CE3-CD 4.3Å; W334-K338 HydrophobicContact CE3-CG 4.24Å; W334-K338 HydrophobicContact CZ3-CG 4.5Å; W334-K338 WeakPolarHBondContact O-CG 3.11Å; W334-K338 PolarHBondContact O-N 2.93Å; W334-K338 VanDerWaalsContact O-N 3.09Å
335	L	80.1	Confident	78.2	Confident	99 Å²	99	111.2 Å²	111.2	52%	0.518	55%	0.547	S	S	.	.	H	α-helix	trans	-68.8	-40.7	173.9	-175	144.9	0	0	0	111.2	N332 R333 K338 I339	N332-L335 WeakPolarHBondContact O-CB 3.27Å; N332-L335 PolarHBondContact O-N 3.46Å; N332-L335 VanDerWaalsContact O-N 3.15Å; R333-L335 VanDerWaalsContact C-N 3.31Å; R333-L335 PolarHBondContact O-N 3.45Å; L335-K338 PolarHBondContact O-N 3.36Å; L335-I339 HydrophobicContact CD2-CD1 3.6Å; L335-I339 HydrophobicContact CG-CD1 4.45Å; L335-I339 WeakPolarHBondContact O-CG1 3.45Å; L335-I339 PolarHBondContact O-N 3.1Å; L335-I339 VanDerWaalsContact O-N 3.1Å
336	M	77.5	Confident	78.9	Confident	130 Å²	130	109.5 Å²	109.5	64%	0.64	54%	0.543	S	S	*	.	H	α-helix	trans	-63.9	-42.4	175.7	-152.8	-78.4	-103.6	0	0	111.6	N332 R333 K338 I339 F340	N332-M336 PolarHBondContact O-N 3.26Å; R333-M336 PolarHBondContact O-N 3.06Å; M336-K338 PolarHBondContact O-N 3.49Å; M336-I339 PolarHBondContact O-N 3.46Å; M336-F340 WeakPolarHBondContact O-CB 3.35Å; M336-F340 PolarHBondContact O-N 3.04Å
337	V	83.9	Confident	79.6	Confident	84 Å²	84	109.2 Å²	109.2	51%	0.509	54%	0.542	S	S	.	.	H	α-helix	trans	-61.4	-42.4	175.2	171.8	0	0	0	0	112	R333 F340 L341	R333-V337 WeakPolarHBondContact O-CG2 3.45Å; R333-V337 PolarHBondContact O-N 3.3Å; V337-F340 PolarHBondContact O-N 3.32Å; V337-L341 WeakPolarHBondContact O-CB 3.39Å; V337-L341 PolarHBondContact O-N 3.03Å
338	K	87.3	Confident	80.6	Confident	124 Å²	124	107 Å²	107	54%	0.539	53%	0.534	S	S	.	.	H	α-helix	trans	-62	-43.9	177.1	-76.9	174	172.1	176.8	0	112.2	W334 L335 M336 F340 L341 I342	W334-K338 HydrophobicContact CE3-CD 4.3Å; W334-K338 HydrophobicContact CE3-CG 4.24Å; W334-K338 HydrophobicContact CZ3-CG 4.5Å; W334-K338 WeakPolarHBondContact O-CG 3.11Å; W334-K338 PolarHBondContact O-N 2.93Å; W334-K338 VanDerWaalsContact O-N 3.09Å; L335-K338 PolarHBondContact O-N 3.36Å; M336-K338 PolarHBondContact O-N 3.49Å; K338-F340 VanDerWaalsContact C-N 3.34Å; K338-L341 PolarHBondContact O-N 3.33Å; K338-I342 WeakPolarHBondContact O-CG1 3.37Å; K338-I342 PolarHBondContact O-N 3.47Å; K338-I342 VanDerWaalsContact O-N 3.15Å
339	I	86.4	Confident	81.5	Confident	94 Å²	94	108.1 Å²	108.1	48%	0.482	53%	0.534	S	S	.	.	H	α-helix	trans	-64.1	-41.5	176.3	-67.7	170.8	0	0	0	110.6	L335 M336 L341 I342 L343	L335-I339 HydrophobicContact CD2-CD1 3.6Å; L335-I339 HydrophobicContact CG-CD1 4.45Å; L335-I339 WeakPolarHBondContact O-CG1 3.45Å; L335-I339 PolarHBondContact O-N 3.1Å; L335-I339 VanDerWaalsContact O-N 3.1Å; M336-I339 PolarHBondContact O-N 3.46Å; I339-L341 PolarHBondContact O-N 3.33Å; I339-I342 PolarHBondContact O-N 3.09Å; I339-L343 PolarHBondContact O-N 3.38Å
340	F	89	Confident	82.7	Confident	124 Å²	124	109.3 Å²	109.3	54%	0.544	53%	0.533	S	S	.	.	H	α-helix	trans	-63.7	-40.1	178	-173.9	-107	0	0	0	112.8	M336 V337 K338 L343 I344	M336-F340 WeakPolarHBondContact O-CB 3.35Å; M336-F340 PolarHBondContact O-N 3.04Å; V337-F340 PolarHBondContact O-N 3.32Å; K338-F340 VanDerWaalsContact C-N 3.34Å; F340-L343 PolarHBondContact O-N 3.23Å; F340-I344 HydrophobicContact CD1-CD1 3.82Å; F340-I344 HydrophobicContact CE1-CD1 3.38Å; F340-I344 HydrophobicContact CE1-CG1 4.26Å; F340-I344 HydrophobicContact CZ-CD1 3.9Å; F340-I344 HydrophobicContact CZ-CG1 4.44Å; F340-I344 PolarHBondContact O-N 3.31Å
341	L	90.5	Very high	84.1	Confident	102 Å²	102	109.6 Å²	109.6	53%	0.534	54%	0.535	S	S	.	.	H	α-helix	trans	-66.5	-40	177.8	-149.3	165.4	0	0	0	111.3	V337 K338 I339 L343 I344 V345	V337-L341 WeakPolarHBondContact O-CB 3.39Å; V337-L341 PolarHBondContact O-N 3.03Å; K338-L341 PolarHBondContact O-N 3.33Å; I339-L341 PolarHBondContact O-N 3.33Å; L341-L343 VanDerWaalsContact C-N 3.32Å; L341-L343 PolarHBondContact O-N 3.02Å; L341-I344 PolarHBondContact O-N 2.87Å; L341-V345 HydrophobicContact CD2-CG2 3.96Å; L341-V345 WeakPolarHBondContact O-CG2 3.49Å; L341-V345 PolarHBondContact O-N 3.24Å
342	I	90.1	Very high	85.4	Confident	120 Å²	120	110.4 Å²	110.4	62%	0.615	54%	0.536	S	S	*	.	H	α-helix	trans	-60.7	-41.9	173.3	-73.6	162.4	0	0	0	111.1	K338 I339 V345 F346	K338-I342 WeakPolarHBondContact O-CG1 3.37Å; K338-I342 PolarHBondContact O-N 3.47Å; K338-I342 VanDerWaalsContact O-N 3.15Å; I339-I342 PolarHBondContact O-N 3.09Å; I342-V345 PolarHBondContact O-N 3.15Å; I342-F346 WeakPolarHBondContact O-CB 3.38Å; I342-F346 PolarHBondContact O-N 3.01Å
343	L	89.3	Confident	86	Confident	105 Å²	105	114 Å²	114	55%	0.55	55%	0.547	S	S	.	.	H	α-helix	trans	-64.4	-38.7	175.8	-73	175.6	0	0	0	112.7	I339 F340 L341 F346 F347	I339-L343 PolarHBondContact O-N 3.38Å; F340-L343 PolarHBondContact O-N 3.23Å; L341-L343 VanDerWaalsContact C-N 3.32Å; L341-L343 PolarHBondContact O-N 3.02Å; L343-F346 PolarHBondContact O-N 3.12Å; L343-F347 WeakPolarHBondContact O-CB 3.36Å; L343-F347 PolarHBondContact O-N 3.43Å
344	I	89.3	Confident	86	Confident	74 Å²	74	110.9 Å²	110.9	38%	0.379	54%	0.544	S	S	.	.	H	α-helix	trans	-64.2	-45.9	175.5	-73.6	174.5	0	0	0	111.1	F340 L341 F346 F347 I348	F340-I344 HydrophobicContact CD1-CD1 3.82Å; F340-I344 HydrophobicContact CE1-CD1 3.38Å; F340-I344 HydrophobicContact CE1-CG1 4.26Å; F340-I344 HydrophobicContact CZ-CD1 3.9Å; F340-I344 HydrophobicContact CZ-CG1 4.44Å; F340-I344 PolarHBondContact O-N 3.31Å; L341-I344 PolarHBondContact O-N 2.87Å; I344-F346 VanDerWaalsContact C-N 3.32Å; I344-F346 PolarHBondContact O-N 2.94Å; I344-F347 WeakPolarHBondContact O-CB 3.48Å; I344-F347 PolarHBondContact O-N 3.32Å; I344-I348 HydrophobicContact CG2-CD1 3.94Å; I344-I348 HydrophobicContact CG2-CG1 4.48Å; I344-I348 WeakPolarHBondContact O-CG1 3.14Å; I344-I348 PolarHBondContact O-N 2.91Å
345	V	91.2	Very high	85.1	Confident	71 Å²	71	107.8 Å²	107.8	43%	0.43	56%	0.559	S	S	.	*	H	α-helix	trans	-62.1	-44	178.5	171.7	0	0	0	0	110.3	L341 I342 F347 I348 I349	L341-V345 HydrophobicContact CD2-CG2 3.96Å; L341-V345 WeakPolarHBondContact O-CG2 3.49Å; L341-V345 PolarHBondContact O-N 3.24Å; I342-V345 PolarHBondContact O-N 3.15Å; V345-F347 VanDerWaalsContact C-N 3.34Å; V345-F347 PolarHBondContact O-N 2.85Å; V345-I348 PolarHBondContact O-N 3.37Å; V345-I349 HydrophobicContact CG1-CD1 3.9Å; V345-I349 WeakPolarHBondContact O-CG1 3.34Å; V345-I349 PolarHBondContact O-N 2.96Å
346	F	88.9	Confident	85.4	Confident	129 Å²	129	108.3 Å²	108.3	57%	0.566	56%	0.561	S	S	*	*	H	α-helix	trans	-60.3	-43	174.8	-176.4	-97.4	0	0	0	112.1	I342 L343 I344 I349 F350	I342-F346 WeakPolarHBondContact O-CB 3.38Å; I342-F346 PolarHBondContact O-N 3.01Å; L343-F346 PolarHBondContact O-N 3.12Å; I344-F346 VanDerWaalsContact C-N 3.32Å; I344-F346 PolarHBondContact O-N 2.94Å; F346-I349 PolarHBondContact O-N 2.89Å; F346-F350 VanDerWaalsContact O-CB 3.27Å; F346-F350 WeakPolarHBondContact O-CB 3.42Å; F346-F350 PolarHBondContact O-N 3.46Å
347	F	89.9	Confident	85.8	Confident	136 Å²	136	107.1 Å²	107.1	60%	0.596	56%	0.556	S	S	*	*	H	α-helix	trans	-61.9	-43.3	176.7	178.9	-97.6	0	0	0	112.3	L343 I344 V345 F350 V351	L343-F347 WeakPolarHBondContact O-CB 3.36Å; L343-F347 PolarHBondContact O-N 3.43Å; I344-F347 WeakPolarHBondContact O-CB 3.48Å; I344-F347 PolarHBondContact O-N 3.32Å; V345-F347 VanDerWaalsContact C-N 3.34Å; V345-F347 PolarHBondContact O-N 2.85Å; F347-F350 PolarHBondContact O-N 3.4Å; F347-V351 HydrophobicContact CD1-CG2 4.25Å; F347-V351 HydrophobicContact CD2-CG2 4.46Å; F347-V351 HydrophobicContact CE1-CG2 3.83Å; F347-V351 HydrophobicContact CE2-CG2 4.06Å; F347-V351 HydrophobicContact CZ-CG2 3.72Å; F347-V351 WeakPolarHBondContact O-CG2 3.45Å; F347-V351 PolarHBondContact O-N 3.42Å
348	I	89	Confident	85.9	Confident	96 Å²	96	108.4 Å²	108.4	49%	0.492	56%	0.559	S	S	.	*	H	α-helix	trans	-63.7	-46	177.1	-68.2	171.4	0	0	0	110.5	I344 V345 F350 V351 V352	I344-I348 HydrophobicContact CG2-CD1 3.94Å; I344-I348 HydrophobicContact CG2-CG1 4.48Å; I344-I348 WeakPolarHBondContact O-CG1 3.14Å; I344-I348 PolarHBondContact O-N 2.91Å; V345-I348 PolarHBondContact O-N 3.37Å; I348-F350 VanDerWaalsContact C-N 3.3Å; I348-F350 PolarHBondContact O-N 3.15Å; I348-V351 PolarHBondContact O-N 3.46Å; I348-V352 HydrophobicContact CG2-CG2 4.36Å; I348-V352 WeakPolarHBondContact O-CB 3.45Å; I348-V352 VanDerWaalsContact O-CG2 3.28Å; I348-V352 WeakPolarHBondContact O-CG2 3.48Å; I348-V352 PolarHBondContact O-N 2.98Å
349	I	88.5	Confident	85.8	Confident	89 Å²	89	107.5 Å²	107.5	46%	0.456	56%	0.56	S	S	.	*	H	α-helix	trans	-59.5	-45.3	176.4	-68.5	169.2	0	0	0	110.1	V345 F346 V352 F353	V345-I349 HydrophobicContact CG1-CD1 3.9Å; V345-I349 WeakPolarHBondContact O-CG1 3.34Å; V345-I349 PolarHBondContact O-N 2.96Å; F346-I349 PolarHBondContact O-N 2.89Å; I349-V352 PolarHBondContact O-N 3.45Å; I349-F353 HydrophobicContact CG2-CD2 3.95Å; I349-F353 HydrophobicContact CG2-CE2 4.43Å; I349-F353 WeakPolarHBondContact O-CB 3.46Å; I349-F353 WeakPolarHBondContact O-CD2 3.41Å; I349-F353 PolarHBondContact O-N 2.96Å
350	F	89.7	Confident	85.8	Confident	102 Å²	102	108.3 Å²	108.3	45%	0.447	57%	0.565	S	S	.	*	H	α-helix	trans	-60.3	-46.9	177.9	-177.3	-89.3	0	0	0	111.8	F346 F347 I348 V352 F353 L354	F346-F350 VanDerWaalsContact O-CB 3.27Å; F346-F350 WeakPolarHBondContact O-CB 3.42Å; F346-F350 PolarHBondContact O-N 3.46Å; F347-F350 PolarHBondContact O-N 3.4Å; I348-F350 VanDerWaalsContact C-N 3.3Å; I348-F350 PolarHBondContact O-N 3.15Å; F350-V352 VanDerWaalsContact C-N 3.34Å; F350-V352 PolarHBondContact O-N 3.33Å; F350-F353 PolarHBondContact O-N 2.99Å; F350-L354 HydrophobicContact CD2-CD1 3.67Å; F350-L354 HydrophobicContact CE1-CB 4.43Å; F350-L354 HydrophobicContact CE1-CD1 4.28Å; F350-L354 HydrophobicContact CE2-CD1 3.15Å; F350-L354 HydrophobicContact CE2-CG 4.42Å; F350-L354 HydrophobicContact CG-CD1 4.43Å; F350-L354 HydrophobicContact CZ-CB 4.45Å; F350-L354 HydrophobicContact CZ-CD1 3.51Å; F350-L354 HydrophobicContact CZ-CG 4.48Å; F350-L354 WeakPolarHBondContact O-CA 3.28Å; F350-L354 WeakPolarHBondContact O-CB 3.32Å; F350-L354 PolarHBondContact O-N 3.32Å
351	V	89	Confident	85.5	Confident	65 Å²	65	107.3 Å²	107.3	39%	0.394	57%	0.566	S	S	.	*	H	α-helix	trans	-65	-38.3	178.7	172	0	0	0	0	111.7	F347 I348 A355	F347-V351 HydrophobicContact CD1-CG2 4.25Å; F347-V351 HydrophobicContact CD2-CG2 4.46Å; F347-V351 HydrophobicContact CE1-CG2 3.83Å; F347-V351 HydrophobicContact CE2-CG2 4.06Å; F347-V351 HydrophobicContact CZ-CG2 3.72Å; F347-V351 WeakPolarHBondContact O-CG2 3.45Å; F347-V351 PolarHBondContact O-N 3.42Å; I348-V351 PolarHBondContact O-N 3.46Å; V351-A355 WeakPolarHBondContact O-CB 3.43Å; V351-A355 PolarHBondContact O-N 2.99Å; V351-A355 VanDerWaalsContact O-N 3.12Å
352	V	88.2	Confident	85.2	Confident	100 Å²	100	107.6 Å²	107.6	61%	0.606	57%	0.569	S	S	*	*	H	α-helix	trans	-74.8	-28.9	-178.4	171	0	0	0	0	113.1	I348 I349 F350	I348-V352 HydrophobicContact CG2-CG2 4.36Å; I348-V352 WeakPolarHBondContact O-CB 3.45Å; I348-V352 VanDerWaalsContact O-CG2 3.28Å; I348-V352 WeakPolarHBondContact O-CG2 3.48Å; I348-V352 PolarHBondContact O-N 2.98Å; I349-V352 PolarHBondContact O-N 3.45Å; F350-V352 VanDerWaalsContact C-N 3.34Å; F350-V352 PolarHBondContact O-N 3.33Å
353	F	80.9	Confident	84.8	Confident	174 Å²	174	106.7 Å²	106.7	76%	0.763	57%	0.565	S	S	*	*	H	α-helix	trans	-99.6	-18.4	-178.4	-85.5	-87.6	0	0	0	114.3	I349 F350	I349-F353 HydrophobicContact CG2-CD2 3.95Å; I349-F353 HydrophobicContact CG2-CE2 4.43Å; I349-F353 WeakPolarHBondContact O-CB 3.46Å; I349-F353 WeakPolarHBondContact O-CD2 3.41Å; I349-F353 PolarHBondContact O-N 2.96Å; F350-F353 PolarHBondContact O-N 2.99Å
354	L	71.6	Confident	84.4	Confident	121 Å²	121	106.8 Å²	106.8	63%	0.634	57%	0.566	S	S	*	*	H	α-helix	trans	-115	-10.4	-176.2	-121.1	162.2	0	0	0	113.7	F350	F350-L354 HydrophobicContact CD2-CD1 3.67Å; F350-L354 HydrophobicContact CE1-CB 4.43Å; F350-L354 HydrophobicContact CE1-CD1 4.28Å; F350-L354 HydrophobicContact CE2-CD1 3.15Å; F350-L354 HydrophobicContact CE2-CG 4.42Å; F350-L354 HydrophobicContact CG-CD1 4.43Å; F350-L354 HydrophobicContact CZ-CB 4.45Å; F350-L354 HydrophobicContact CZ-CD1 3.51Å; F350-L354 HydrophobicContact CZ-CG 4.48Å; F350-L354 WeakPolarHBondContact O-CA 3.28Å; F350-L354 WeakPolarHBondContact O-CB 3.32Å; F350-L354 PolarHBondContact O-N 3.32Å
355	A	57.1	Low	84	Confident	125 Å²	125	109.8 Å²	109.8	100%	1.033	58%	0.583	S	S	*	*			trans	-94.5	0	154.5	0	0	0	0	0	109	V351	V351-A355 WeakPolarHBondContact O-CB 3.43Å; V351-A355 PolarHBondContact O-N 2.99Å; V351-A355 VanDerWaalsContact O-N 3.12Å

Retrieved 355 of 355 residues in 738.6 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).