A0A096NMG1_PAPAN Loading...

Dual specificity mitogen-activated protein kinase kinase 5

Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. As part of the MAPK/ERK signaling pathway, acts as a negative regulator of apoptosis in cardiomyocytes via promotion of STUB1/CHIP-mediated ubiquitination and degradation of ICER-type isoforms of CREM.

AlphaFold DB (A0A2J8UC74), UniProt , Accession A0A096NMG1, Species PAPAN (Papio anubis, Olive baboon), Gene MAP2K5, Length 448 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33.5	Very low	37.3	Very low	239 Å²	239	142.5 Å²	142.5	100%	1.177	80%	0.796	S	S	*	*				0	112.9	0	-77.1	-158.1	-102.4	0	0	105.8
2	L	30.7	Very low	38.4	Very low	133 Å²	133	133.8 Å²	133.8	70%	0.696	75%	0.745	S	S	*	*			cis	-143.4	129.7	29.3	-130.4	81.4	0	0	0	108.2	L4	L2-L4 HydrophobicContact CD2-CD1 3.65Å; L2-L4 HydrophobicContact CD2-CG 4.13Å
3	W	33.8	Very low	39.2	Very low	257 Å²	257	136.4 Å²	136.4	97%	0.973	75%	0.748	S	S	*	*			trans	-89	121.3	153	-92.1	53.1	0	0	0	106.6
4	L	36.9	Very low	40	Very low	141 Å²	141	138.1 Å²	138.1	74%	0.738	76%	0.756	S	S	*	*			trans	-141.1	98.7	155.9	-81.3	173.1	0	0	0	104.9	L2	L2-L4 HydrophobicContact CD2-CD1 3.65Å; L2-L4 HydrophobicContact CD2-CG 4.13Å
5	A	40.8	Very low	41.6	Very low	87 Å²	87	132.9 Å²	132.9	72%	0.719	72%	0.724	S	S	*	*				60.7	80	90.4	0	0	0	0	0	112.5
6	L	34.1	Very low	43.5	Very low	147 Å²	147	130 Å²	130	77%	0.77	71%	0.712	S	S	*	*			trans	-121.5	117.5	150.3	-72.1	172.6	0	0	0	106.8	F9	L6-F9 HydrophobicContact CD1-CZ 4.38Å
7	G	35.3	Very low	46	Very low	56 Å²	56	122.5 Å²	122.5	58%	0.577	67%	0.671	S	S	*	*			trans	-68.3	-168.3	177.2	0	0	0	0	0	112.6	F9	G7-F9 PolarHBondContact O-N 2.94Å; G7-F9 VanDerWaalsContact O-N 3.16Å
8	P	38.7	Very low	48.4	Very low	124 Å²	124	117.9 Å²	117.9	81%	0.805	65%	0.647	S	S	*	*			trans	-62.8	121.5	-179.2	21.2	-20.4	0	0	0	109.2	P10	P8-P10 WeakPolarHBondContact O-CD 3.32Å; P8-P10 WeakPolarHBondContact O-CG 3.37Å
9	F	45.8	Very low	50.6	Low	168 Å²	168	111.8 Å²	111.8	74%	0.737	61%	0.613	S	S	*	*			trans	-59.2	108.5	-180	-79.1	-90	0	0	0	110.8	L6 G7	L6-F9 HydrophobicContact CD1-CZ 4.38Å; G7-F9 PolarHBondContact O-N 2.94Å; G7-F9 VanDerWaalsContact O-N 3.16Å
10	P	38.6	Very low	52.7	Low	124 Å²	124	109.7 Å²	109.7	81%	0.805	60%	0.596	S	S	*	*			trans	-95.5	17.4	-174.3	12.2	7.5	0	0	0	114	P8	P8-P10 WeakPolarHBondContact O-CD 3.32Å; P8-P10 WeakPolarHBondContact O-CG 3.37Å
11	A	42.5	Very low	54.6	Low	92 Å²	92	104.5 Å²	104.5	76%	0.76	57%	0.567	S	S	*	*	S	Bend	trans	-119.9	7.6	-168.3	0	0	0	0	0	116
12	M	50.6	Low	57.3	Low	37 Å²	37	96.3 Å²	96.3	18%	0.182	53%	0.525	C	S	.	.			trans	-121.1	13.1	-171.7	-73.4	-100.3	-137	0	0	114.4	N14 Q15 Y86 M90	M12-N14 PolarHBondContact O-N 2.81Å; M12-Q15 PolarHBondContact SD-OE1 3.48Å; M12-Q15 VanDerWaalsContact SD-OE1 3.34Å; M12-Y86 HydrophobicContact CE-CD1 3.73Å; M12-Y86 HydrophobicContact CE-CG 3.96Å; M12-Y86 HydrophobicContact SD-CD1 3.85Å; M12-Y86 HydrophobicContact SD-CE1 4.24Å; M12-M90 HydrophobicContact CE-CE 3.27Å; M12-M90 HydrophobicContact CE-CG 3.75Å; M12-M90 HydrophobicContact CE-SD 4.07Å; M12-M90 HydrophobicContact SD-CE 3.59Å; M12-M90 VanDerWaalsContact SD-CE 3.59Å
13	E	48.9	Very low	59.8	Low	168 Å²	168	91.3 Å²	91.3	79%	0.785	50%	0.499	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.5	-10	-178.4	-95.3	175.6	166.7	0	0	114.5
14	N	50.3	Low	61.8	Low	160 Å²	160	82.3 Å²	82.3	86%	0.856	47%	0.474	S	S	*	.	T	Hydrogen-bonded Turn	trans	-128.4	11	-175.3	-87.7	-23.2	0	0	0	115.3	M12 V16	M12-N14 PolarHBondContact O-N 2.81Å; N14-V16 PolarHBondContact O-N 3.46Å
15	Q	63.5	Low	63.2	Low	60 Å²	60	83.8 Å²	83.8	28%	0.28	48%	0.482	S	S	.	.			trans	-79.1	121.8	173.3	-91	-170.7	-0.2	0	0	110.7	M12 L17	M12-Q15 PolarHBondContact SD-OE1 3.48Å; M12-Q15 VanDerWaalsContact SD-OE1 3.34Å; Q15-L17 PolarHBondContact O-N 3.29Å
16	V	71.4	Confident	64.6	Low	87 Å²	87	84.2 Å²	84.2	53%	0.527	48%	0.48	S	S	.	.			trans	-68.8	114.7	173.9	178.9	0	0	0	0	108.5	N14 T32	N14-V16 PolarHBondContact O-N 3.46Å; V16-T32 HydrophobicContact CG1-CG2 3.22Å
17	L	86.1	Confident	66.9	Low	3 Å²	3	79.6 Å²	79.6	2%	0.016	47%	0.468	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-85.3	129.1	174.8	171.4	67.6	0	0	0	108.6	Q15 I19 V33 L39 L82 Y85 L102	Q15-L17 PolarHBondContact O-N 3.29Å; L17-I19 HydrophobicContact CD2-CD1 4.06Å; L17-I19 HydrophobicContact CD2-CG1 4.05Å; L17-I19 HydrophobicContact CG-CG1 4.01Å; L17-V33 HydrophobicContact CB-CB 4.16Å; L17-V33 HydrophobicContact CD2-CB 4.44Å; L17-V33 HydrophobicContact CG-CB 4.48Å; L17-V33 PolarHBondContact N-O 2.82Å; L17-V33 VanDerWaalsContact N-O 3.13Å; L17-V33 PolarHBondContact O-N 2.69Å; L17-L39 HydrophobicContact CD2-CD2 4.25Å; L17-L82 HydrophobicContact CD2-CD2 3.74Å; L17-Y85 HydrophobicContact CD1-CD1 3.85Å; L17-Y85 HydrophobicContact CD1-CE1 3.32Å; L17-L102 HydrophobicContact CD1-CB 4.32Å
18	V	88.9	Confident	69.4	Low	40 Å²	40	79.2 Å²	79.2	24%	0.242	46%	0.459	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-109.4	120.5	171.9	-175.2	0	0	0	0	108.2	D30 P101 L102	V18-D30 HydrophobicContact CG1-CB 3.99Å; V18-P101 HydrophobicContact CB-CB 4.13Å; V18-P101 HydrophobicContact CB-CG 4.46Å; V18-P101 HydrophobicContact CG1-CB 3.97Å; V18-P101 HydrophobicContact CG1-CG 4.21Å; V18-P101 WeakPolarHBondContact O-CA 3.43Å; V18-P101 WeakPolarHBondContact O-CB 3.43Å; V18-L102 PolarHBondContact O-N 3.43Å
19	I	91.9	Very high	71.8	Confident	1 Å²	1	76.1 Å²	76.1	1%	0.005	44%	0.438	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.4	120.2	176.5	-58.7	-177.1	0	0	0	108.5	L17 I21 D30 W31 V33 L39 V44 L102 I104	L17-I19 HydrophobicContact CD2-CD1 4.06Å; L17-I19 HydrophobicContact CD2-CG1 4.05Å; L17-I19 HydrophobicContact CG-CG1 4.01Å; I19-I21 HydrophobicContact CG2-CG1 4.24Å; I19-D30 WeakPolarHBondContact O-CA 3.49Å; I19-W31 HydrophobicContact CD1-CE3 4.13Å; I19-W31 HydrophobicContact CD1-CZ3 4.25Å; I19-W31 PolarHBondContact N-O 2.86Å; I19-W31 PolarHBondContact O-N 2.97Å; I19-V33 HydrophobicContact CD1-CG2 3.99Å; I19-V33 HydrophobicContact CG1-CG2 4.26Å; I19-L39 HydrophobicContact CD1-CD2 3.57Å; I19-V44 HydrophobicContact CD1-CG2 4.43Å; I19-L102 CarbonylContact C-O 3.55Å; I19-L102 WeakPolarHBondContact CA-O 3.08Å; I19-L102 HydrophobicContact CG1-CD2 4.4Å; I19-I104 HydrophobicContact CG2-CD1 3.65Å; I19-I104 HydrophobicContact CG2-CG1 3.76Å; I19-I104 HydrophobicContact CG2-CG2 4.13Å
20	R	92.6	Very high	73.9	Confident	70 Å²	70	71.8 Å²	71.8	26%	0.264	42%	0.422	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-95.2	104.9	175.5	178.5	164.6	-71.1	164	0.3	110.1	K22 A28 D30 P101 L102 Q103 I104	R20-K22 PolarHBondContact O-N 3.24Å; R20-A28 HydrophobicContact CG-CB 3.79Å; R20-D30 VanDerWaalsContact CB-OD1 3.29Å; R20-D30 WeakPolarHBondContact CB-OD1 3.47Å; R20-D30 VanDerWaalsContact CG-OD1 3.26Å; R20-D30 WeakPolarHBondContact CG-OD1 3.42Å; R20-D30 IonicContact CZ-OD1 3.49Å; R20-D30 IonicContact CZ-OD2 2.75Å; R20-D30 IonicContact NE-OD1 2.81Å; R20-D30 PolarHBondContact NE-OD1 2.95Å; R20-D30 IonicContact NE-OD2 3.35Å; R20-D30 IonicContact NH2-OD1 2.82Å; R20-D30 PolarHBondContact NH2-OD1 3Å; R20-D30 IonicContact NH2-OD2 3.55Å; R20-D30 PolarHBondContact NH2-OD2 3.14Å; R20-P101 HydrophobicContact CB-CB 4.02Å; R20-L102 PolarHBondContact N-O 3.44Å; R20-Q103 HydrophobicContact CB-CG 4.45Å; R20-Q103 WeakPolarHBondContact O-CA 3.12Å; R20-I104 PolarHBondContact O-N 3.46Å
21	I	92.2	Very high	76.4	Confident	0 Å²	0	69 Å²	69	0%	0	40%	0.396	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-84.4	112.1	178.3	-50	-178.2	0	0	0	108.8	I19 I23 A28 V29 V47 I48 V51 I104 P106	I19-I21 HydrophobicContact CG2-CG1 4.24Å; I21-I23 PolarHBondContact O-N 2.89Å; I21-A28 CarbonylContact O-C 3.59Å; I21-A28 VanDerWaalsContact O-CA 3.25Å; I21-A28 WeakPolarHBondContact O-CA 3.41Å; I21-V29 PolarHBondContact N-O 3.39Å; I21-V29 PolarHBondContact O-N 3.16Å; I21-V47 HydrophobicContact CD1-CG1 3.7Å; I21-I48 HydrophobicContact CD1-CG1 4.17Å; I21-I48 HydrophobicContact CG2-CG1 4.16Å; I21-V51 HydrophobicContact CD1-CG2 4.4Å; I21-I104 HydrophobicContact CB-CG1 4.36Å; I21-I104 HydrophobicContact CG1-CD1 4.02Å; I21-I104 HydrophobicContact CG1-CG1 4.02Å; I21-I104 HydrophobicContact CG2-CG1 4.44Å; I21-P106 HydrophobicContact CG2-CG 3.57Å
22	K	89.9	Confident	78.5	Confident	68 Å²	68	67.7 Å²	67.7	30%	0.296	38%	0.378	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-81.4	113.3	179	-67.6	-78.8	-170.9	172.2	0	110.2	R20 A28 I104 F105 P106	R20-K22 PolarHBondContact O-N 3.24Å; K22-A28 HydrophobicContact CD-CB 4.02Å; K22-I104 WeakPolarHBondContact CB-O 3.42Å; K22-I104 PolarHBondContact N-O 3.32Å; K22-F105 HydrophobicContact CB-CD1 3.65Å; K22-F105 HydrophobicContact CB-CE1 3.78Å; K22-F105 HydrophobicContact CB-CG 4.27Å; K22-F105 HydrophobicContact CB-CZ 4.45Å; K22-F105 HydrophobicContact CD-CE1 4.27Å; K22-F105 HydrophobicContact CG-CD1 3.92Å; K22-F105 HydrophobicContact CG-CE1 3.55Å; K22-F105 HydrophobicContact CG-CE2 4.36Å; K22-F105 HydrophobicContact CG-CG 4.5Å; K22-F105 HydrophobicContact CG-CZ 3.79Å; K22-P106 WeakPolarHBondContact O-CD 3.4Å
23	I	83.3	Confident	80.2	Confident	27 Å²	27	66.3 Å²	66.3	14%	0.138	37%	0.372	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.3	124.3	-179.2	-54.6	174	0	0	0	109.1	I21 N25 S26 G27 V29 V51 L52	I21-I23 PolarHBondContact O-N 2.89Å; I23-N25 PolarHBondContact O-N 2.87Å; I23-N25 VanDerWaalsContact O-N 3.12Å; I23-S26 PolarHBondContact O-N 2.85Å; I23-G27 PolarHBondContact N-O 3.5Å; I23-V29 HydrophobicContact CD1-CG2 3.67Å; I23-V51 HydrophobicContact CD1-CG1 3.3Å; I23-V51 HydrophobicContact CG1-CG1 3.64Å; I23-L52 HydrophobicContact CG2-CD2 3.72Å
24	P	74.8	Confident	81.3	Confident	68 Å²	68	65.3 Å²	65.3	44%	0.442	37%	0.367	S	S	.	.	T	Hydrogen-bonded Turn	trans	-54.7	121.3	174.5	-23.9	33.5	0	0	0	110.7	S26	P24-S26 PolarHBondContact O-N 2.99Å; P24-S26 VanDerWaalsContact O-N 3.17Å
25	N	67.3	Low	82.2	Confident	173 Å²	173	60.9 Å²	60.9	93%	0.925	35%	0.349	S	S	*	.	T	Hydrogen-bonded Turn	trans	63.6	11.4	177.1	-47.7	-39.6	0	0	0	116.5	I23	I23-N25 PolarHBondContact O-N 2.87Å; I23-N25 VanDerWaalsContact O-N 3.12Å
26	S	70	Confident	82.3	Confident	96 Å²	96	58 Å²	58	67%	0.671	34%	0.336	S	S	*	.	T	Hydrogen-bonded Turn	trans	-139.9	15.3	-178	-54.7	0	0	0	0	115.3	I23 P24	I23-S26 PolarHBondContact O-N 2.85Å; P24-S26 PolarHBondContact O-N 2.99Å; P24-S26 VanDerWaalsContact O-N 3.17Å
27	G	82.6	Confident	82.1	Confident	50 Å²	50	57.8 Å²	57.8	52%	0.515	34%	0.336	S	S	.	.	E	Extended strand (participates in β ladder)	trans	96.4	-143	173.2	0	0	0	0	0	113.3	I23	I23-G27 PolarHBondContact N-O 3.5Å
28	A	87.8	Confident	81.4	Confident	47 Å²	47	65 Å²	65	39%	0.388	37%	0.369	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-141.1	149	-179.4	0	0	0	0	0	110.8	R20 I21 K22	R20-A28 HydrophobicContact CG-CB 3.79Å; I21-A28 CarbonylContact O-C 3.59Å; I21-A28 VanDerWaalsContact O-CA 3.25Å; I21-A28 WeakPolarHBondContact O-CA 3.41Å; K22-A28 HydrophobicContact CD-CB 4.02Å
29	V	88.9	Confident	81.2	Confident	60 Å²	60	64 Å²	64	36%	0.364	36%	0.362	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-122	129.8	175.6	172.5	0	0	0	0	108.8	I21 I23 V51	I21-V29 PolarHBondContact N-O 3.39Å; I21-V29 PolarHBondContact O-N 3.16Å; I23-V29 HydrophobicContact CD1-CG2 3.67Å; V29-V51 HydrophobicContact CB-CG1 4.46Å; V29-V51 HydrophobicContact CG1-CG2 4.37Å; V29-V51 HydrophobicContact CG2-CG1 4.24Å
30	D	90.4	Very high	80.9	Confident	76 Å²	76	68.1 Å²	68.1	41%	0.406	38%	0.384	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.3	127.4	177.5	-70.1	-8.8	0	0	0	109.8	V18 I19 R20	V18-D30 HydrophobicContact CG1-CB 3.99Å; I19-D30 WeakPolarHBondContact O-CA 3.49Å; R20-D30 VanDerWaalsContact CB-OD1 3.29Å; R20-D30 WeakPolarHBondContact CB-OD1 3.47Å; R20-D30 VanDerWaalsContact CG-OD1 3.26Å; R20-D30 WeakPolarHBondContact CG-OD1 3.42Å; R20-D30 IonicContact CZ-OD1 3.49Å; R20-D30 IonicContact CZ-OD2 2.75Å; R20-D30 IonicContact NE-OD1 2.81Å; R20-D30 PolarHBondContact NE-OD1 2.95Å; R20-D30 IonicContact NE-OD2 3.35Å; R20-D30 IonicContact NH2-OD1 2.82Å; R20-D30 PolarHBondContact NH2-OD1 3Å; R20-D30 IonicContact NH2-OD2 3.55Å; R20-D30 PolarHBondContact NH2-OD2 3.14Å
31	W	89.6	Confident	80.7	Confident	66 Å²	66	65.9 Å²	65.9	25%	0.25	38%	0.376	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-114.8	121.1	175.9	177.4	39.5	0	0	0	110.3	I19 V33 L39 D43 V44 V47	I19-W31 HydrophobicContact CD1-CE3 4.13Å; I19-W31 HydrophobicContact CD1-CZ3 4.25Å; I19-W31 PolarHBondContact N-O 2.86Å; I19-W31 PolarHBondContact O-N 2.97Å; W31-V33 HydrophobicContact CD2-CG2 3.8Å; W31-V33 HydrophobicContact CE3-CG2 3.81Å; W31-V33 HydrophobicContact CG-CG2 4.49Å; W31-V33 HydrophobicContact CH2-CG2 4.07Å; W31-V33 HydrophobicContact CZ2-CG2 4.01Å; W31-V33 HydrophobicContact CZ3-CG2 3.95Å; W31-L39 HydrophobicContact CH2-CD1 3.62Å; W31-L39 HydrophobicContact CZ2-CD1 4.47Å; W31-L39 HydrophobicContact CZ3-CD1 4.1Å; W31-D43 HydrophobicContact CH2-CB 4.33Å; W31-V44 HydrophobicContact CZ3-CG2 4.12Å; W31-V47 HydrophobicContact CB-CG1 4.44Å; W31-V47 HydrophobicContact CD2-CB 4.33Å; W31-V47 HydrophobicContact CD2-CG1 3.92Å; W31-V47 HydrophobicContact CD2-CG2 3.97Å; W31-V47 HydrophobicContact CE3-CB 4.12Å; W31-V47 HydrophobicContact CE3-CG1 3.99Å; W31-V47 HydrophobicContact CE3-CG2 4.02Å; W31-V47 HydrophobicContact CG-CG1 4.11Å; W31-V47 HydrophobicContact CH2-CB 4.42Å; W31-V47 HydrophobicContact CH2-CG2 3.62Å; W31-V47 HydrophobicContact CZ2-CG2 3.59Å; W31-V47 HydrophobicContact CZ3-CB 4.16Å; W31-V47 HydrophobicContact CZ3-CG2 3.85Å
32	T	88.7	Confident	80.4	Confident	64 Å²	64	74.4 Å²	74.4	39%	0.393	41%	0.409	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-88.9	121.2	179.1	-54.7	0	0	0	0	110.5	V16	V16-T32 HydrophobicContact CG1-CG2 3.22Å
33	V	84.9	Confident	80.3	Confident	9 Å²	9	74 Å²	74	6%	0.055	41%	0.41	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-109	116.6	-178.5	-178.4	0	0	0	0	109.6	L17 I19 W31 L39	L17-V33 HydrophobicContact CB-CB 4.16Å; L17-V33 HydrophobicContact CD2-CB 4.44Å; L17-V33 HydrophobicContact CG-CB 4.48Å; L17-V33 PolarHBondContact N-O 2.82Å; L17-V33 VanDerWaalsContact N-O 3.13Å; L17-V33 PolarHBondContact O-N 2.69Å; I19-V33 HydrophobicContact CD1-CG2 3.99Å; I19-V33 HydrophobicContact CG1-CG2 4.26Å; W31-V33 HydrophobicContact CD2-CG2 3.8Å; W31-V33 HydrophobicContact CE3-CG2 3.81Å; W31-V33 HydrophobicContact CG-CG2 4.49Å; W31-V33 HydrophobicContact CH2-CG2 4.07Å; W31-V33 HydrophobicContact CZ2-CG2 4.01Å; W31-V33 HydrophobicContact CZ3-CG2 3.95Å; V33-L39 HydrophobicContact CG1-CB 4.43Å; V33-L39 HydrophobicContact CG1-CD1 3.9Å; V33-L39 HydrophobicContact CG1-CD2 4.22Å; V33-L39 HydrophobicContact CG1-CG 4.4Å; V33-L39 HydrophobicContact CG2-CD1 4.41Å; V33-L39 HydrophobicContact CG2-CD2 4.24Å
34	H	72.8	Confident	80.6	Confident	146 Å²	146	72.8 Å²	72.8	68%	0.676	40%	0.404	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.1	-10	-178.1	-61.8	-68	0	0	0	113.9
35	S	69.3	Low	81.1	Confident	68 Å²	68	71.3 Å²	71.3	48%	0.476	39%	0.392	S	S	.	.	T	Hydrogen-bonded Turn	trans	-137	57.5	179.8	-55	0	0	0	0	111.2	P37 Q38 L39	S35-P37 VanDerWaalsContact C-CD 3.48Å; S35-Q38 PolarHBondContact O-N 2.88Å; S35-L39 PolarHBondContact O-N 2.8Å
36	G	64.6	Low	81.9	Confident	0 Å²	0	67 Å²	67	0%	0	37%	0.369	C	S	.	.	G	3₁₀ helix	trans	-50.4	-43.2	-176.5	0	0	0	0	0	115.5	Q38 L39	G36-Q38 PolarHBondContact O-N 3.23Å; G36-L39 VanDerWaalsContact O-CB 3.32Å; G36-L39 WeakPolarHBondContact O-CB 3.42Å; G36-L39 PolarHBondContact O-N 3.39Å
37	P	67	Low	82.7	Confident	82 Å²	82	63.5 Å²	63.5	53%	0.532	34%	0.343	S	S	.	.	G	3₁₀ helix	trans	-67.3	-17.6	179.3	-23.4	34.4	0	0	0	115.4	S35	S35-P37 VanDerWaalsContact C-CD 3.48Å
38	Q	73.1	Confident	82.9	Confident	153 Å²	153	61.1 Å²	61.1	72%	0.715	32%	0.318	S	S	*	.	G	3₁₀ helix	trans	-107.3	3.4	-179.6	-63.5	-178.4	2.9	0	0	112.6	S35 G36 L40	S35-Q38 PolarHBondContact O-N 2.88Å; G36-Q38 PolarHBondContact O-N 3.23Å; Q38-L40 PolarHBondContact O-N 2.71Å
39	L	82.9	Confident	82.6	Confident	19 Å²	19	60.4 Å²	60.4	10%	0.099	32%	0.316	C	S	.	.			trans	-67	124.7	-177.3	-172.9	69.4	0	0	0	110.4	L17 I19 W31 V33 S35 G36 D43 V44 M78	L17-L39 HydrophobicContact CD2-CD2 4.25Å; I19-L39 HydrophobicContact CD1-CD2 3.57Å; W31-L39 HydrophobicContact CH2-CD1 3.62Å; W31-L39 HydrophobicContact CZ2-CD1 4.47Å; W31-L39 HydrophobicContact CZ3-CD1 4.1Å; V33-L39 HydrophobicContact CG1-CB 4.43Å; V33-L39 HydrophobicContact CG1-CD1 3.9Å; V33-L39 HydrophobicContact CG1-CD2 4.22Å; V33-L39 HydrophobicContact CG1-CG 4.4Å; V33-L39 HydrophobicContact CG2-CD1 4.41Å; V33-L39 HydrophobicContact CG2-CD2 4.24Å; S35-L39 PolarHBondContact O-N 2.8Å; G36-L39 VanDerWaalsContact O-CB 3.32Å; G36-L39 WeakPolarHBondContact O-CB 3.42Å; G36-L39 PolarHBondContact O-N 3.39Å; L39-D43 HydrophobicContact CD1-CB 3.88Å; L39-V44 HydrophobicContact CD2-CG2 3.86Å; L39-V44 HydrophobicContact CG-CG2 4.21Å; L39-M78 HydrophobicContact CB-CE 3.92Å; L39-M78 HydrophobicContact CD2-CE 3.35Å; L39-M78 HydrophobicContact CG-CE 3.37Å; L39-M78 WeakPolarHBondContact O-CE 2.94Å
40	L	86.3	Confident	82.2	Confident	88 Å²	88	64.8 Å²	64.8	46%	0.461	33%	0.332	S	S	.	.			trans	-94.9	155.9	178.9	-58.7	175.6	0	0	0	111.4	Q38 R42 D43 V44	Q38-L40 PolarHBondContact O-N 2.71Å; L40-R42 PolarHBondContact O-N 3.36Å; L40-D43 WeakPolarHBondContact CB-OD2 3.45Å; L40-D43 PolarHBondContact N-OD2 2.82Å; L40-D43 WeakPolarHBondContact O-CB 3.42Å; L40-D43 PolarHBondContact O-N 3.16Å; L40-V44 PolarHBondContact O-N 2.78Å
41	F	88.4	Confident	81.9	Confident	23 Å²	23	63 Å²	63	10%	0.101	32%	0.324	C	S	.	.	H	α-helix	trans	-59.2	-37.3	179.6	172.5	-112.4	0	0	0	111.2	D43 V44 L45 F60 V72 R73 D75 M78	F41-D43 VanDerWaalsContact C-N 3.35Å; F41-D43 PolarHBondContact O-N 3.06Å; F41-V44 PolarHBondContact O-N 3.2Å; F41-L45 HydrophobicContact CD1-CD1 4.09Å; F41-L45 HydrophobicContact CE1-CD1 3.44Å; F41-L45 VanDerWaalsContact CE1-CD1 3.44Å; F41-L45 HydrophobicContact CE1-CG 4.07Å; F41-L45 HydrophobicContact CE2-CD1 4.44Å; F41-L45 HydrophobicContact CE2-CD2 4.29Å; F41-L45 HydrophobicContact CE2-CG 4.24Å; F41-L45 HydrophobicContact CZ-CD1 3.64Å; F41-L45 HydrophobicContact CZ-CD2 4.02Å; F41-L45 HydrophobicContact CZ-CG 3.9Å; F41-L45 PolarHBondContact O-N 3.01Å; F41-L45 VanDerWaalsContact O-N 3.13Å; F41-F60 HydrophobicContact CD2-CD1 4.36Å; F41-F60 AromaticContact CD2-CE1 3.49Å; F41-F60 HydrophobicContact CD2-CE1 3.49Å; F41-F60 VanDerWaalsContact CD2-CE1 3.49Å; F41-F60 HydrophobicContact CD2-CZ 4.07Å; F41-F60 AromaticContact CE2-CD1 3.8Å; F41-F60 HydrophobicContact CE2-CD1 3.8Å; F41-F60 AromaticContact CE2-CE1 3.36Å; F41-F60 HydrophobicContact CE2-CE1 3.36Å; F41-F60 HydrophobicContact CE2-CZ 4.2Å; F41-V72 HydrophobicContact CD2-CG1 3.88Å; F41-V72 HydrophobicContact CE2-CG1 4.01Å; F41-V72 WeakPolarHBondContact CE2-O 3.46Å; F41-R73 WeakPolarHBondContact CE1-O 3.48Å; F41-D75 VanDerWaalsContact CB-OD1 3.23Å; F41-D75 WeakPolarHBondContact CB-OD1 3.38Å; F41-D75 PolarHBondContact N-OD1 2.97Å; F41-M78 WeakPolarHBondContact CA-SD 3.29Å; F41-M78 HydrophobicContact CB-SD 3.92Å; F41-M78 PolarHBondContact N-SD 3.36Å
42	R	86.6	Confident	81.4	Confident	179 Å²	179	61.3 Å²	61.3	68%	0.675	32%	0.32	S	S	*	.	H	α-helix	trans	-62.9	-38.3	176.3	-174.3	172.7	-178.8	170.4	1.1	113	L40 V44 L45 D46	L40-R42 PolarHBondContact O-N 3.36Å; R42-V44 VanDerWaalsContact C-N 3.27Å; R42-V44 PolarHBondContact O-N 3.46Å; R42-L45 PolarHBondContact O-N 3.34Å; R42-D46 PolarHBondContact O-N 2.8Å
43	D	87.9	Confident	80.6	Confident	61 Å²	61	63.5 Å²	63.5	33%	0.326	34%	0.335	S	S	.	.	H	α-helix	trans	-63.2	-39.3	-179.5	-56.6	-37.2	0	0	0	110.6	W31 L39 L40 F41 D46 V47	W31-D43 HydrophobicContact CH2-CB 4.33Å; L39-D43 HydrophobicContact CD1-CB 3.88Å; L40-D43 WeakPolarHBondContact CB-OD2 3.45Å; L40-D43 PolarHBondContact N-OD2 2.82Å; L40-D43 WeakPolarHBondContact O-CB 3.42Å; L40-D43 PolarHBondContact O-N 3.16Å; F41-D43 VanDerWaalsContact C-N 3.35Å; F41-D43 PolarHBondContact O-N 3.06Å; D43-D46 PolarHBondContact O-N 2.62Å; D43-V47 WeakPolarHBondContact O-CG2 3.4Å; D43-V47 PolarHBondContact O-N 3.05Å; D43-V47 VanDerWaalsContact O-N 3.1Å
44	V	87.8	Confident	79.7	Confident	1 Å²	1	72 Å²	72	1%	0.006	37%	0.374	C	S	.	.	H	α-helix	trans	-67	-43.1	175.6	-179.9	0	0	0	0	111.1	I19 W31 L39 L40 F41 R42 D46 V47 I48 F60 M78 I104	I19-V44 HydrophobicContact CD1-CG2 4.43Å; W31-V44 HydrophobicContact CZ3-CG2 4.12Å; L39-V44 HydrophobicContact CD2-CG2 3.86Å; L39-V44 HydrophobicContact CG-CG2 4.21Å; L40-V44 PolarHBondContact O-N 2.78Å; F41-V44 PolarHBondContact O-N 3.2Å; R42-V44 VanDerWaalsContact C-N 3.27Å; R42-V44 PolarHBondContact O-N 3.46Å; V44-D46 VanDerWaalsContact C-N 3.33Å; V44-D46 PolarHBondContact O-N 3.3Å; V44-V47 PolarHBondContact O-N 3.06Å; V44-I48 HydrophobicContact CG1-CD1 3.84Å; V44-I48 HydrophobicContact CG1-CG1 4.35Å; V44-I48 WeakPolarHBondContact O-CB 3.44Å; V44-I48 VanDerWaalsContact O-CG1 3.24Å; V44-I48 WeakPolarHBondContact O-CG1 3.5Å; V44-I48 PolarHBondContact O-N 3.34Å; V44-F60 HydrophobicContact CB-CE1 3.86Å; V44-F60 HydrophobicContact CB-CZ 4.27Å; V44-F60 HydrophobicContact CG1-CD1 3.83Å; V44-F60 HydrophobicContact CG1-CE1 3.43Å; V44-F60 VanDerWaalsContact CG1-CE1 3.43Å; V44-F60 HydrophobicContact CG1-CE2 4.46Å; V44-F60 HydrophobicContact CG1-CG 4.49Å; V44-F60 HydrophobicContact CG1-CZ 3.79Å; V44-M78 HydrophobicContact CG2-CE 3.43Å; V44-M78 VanDerWaalsContact CG2-CE 3.43Å; V44-M78 HydrophobicContact CG2-SD 4.48Å; V44-I104 HydrophobicContact CG1-CD1 3.5Å
45	L	86.4	Confident	79.3	Confident	36 Å²	36	66.1 Å²	66.1	19%	0.188	35%	0.351	C	S	.	.	H	α-helix	trans	-62.7	-38.9	175.8	-69.8	-173.8	0	0	0	112.5	F41 R42 I48 G49 T57 F60	F41-L45 HydrophobicContact CD1-CD1 4.09Å; F41-L45 HydrophobicContact CE1-CD1 3.44Å; F41-L45 VanDerWaalsContact CE1-CD1 3.44Å; F41-L45 HydrophobicContact CE1-CG 4.07Å; F41-L45 HydrophobicContact CE2-CD1 4.44Å; F41-L45 HydrophobicContact CE2-CD2 4.29Å; F41-L45 HydrophobicContact CE2-CG 4.24Å; F41-L45 HydrophobicContact CZ-CD1 3.64Å; F41-L45 HydrophobicContact CZ-CD2 4.02Å; F41-L45 HydrophobicContact CZ-CG 3.9Å; F41-L45 PolarHBondContact O-N 3.01Å; F41-L45 VanDerWaalsContact O-N 3.13Å; R42-L45 PolarHBondContact O-N 3.34Å; L45-I48 PolarHBondContact O-N 3.12Å; L45-G49 PolarHBondContact O-N 3.37Å; L45-T57 HydrophobicContact CD2-CG2 4.08Å; L45-F60 HydrophobicContact CD2-CD1 4.19Å
46	D	84.1	Confident	79.3	Confident	84 Å²	84	66.3 Å²	66.3	45%	0.449	35%	0.349	S	S	.	.	H	α-helix	trans	-65.1	-41.2	178.3	-74.6	-17.6	0	0	0	111	R42 D43 V44 G49 Q50	R42-D46 PolarHBondContact O-N 2.8Å; D43-D46 PolarHBondContact O-N 2.62Å; V44-D46 VanDerWaalsContact C-N 3.33Å; V44-D46 PolarHBondContact O-N 3.3Å; D46-G49 PolarHBondContact O-N 2.88Å; D46-Q50 WeakPolarHBondContact O-CG 3.32Å; D46-Q50 PolarHBondContact O-N 2.81Å; D46-Q50 VanDerWaalsContact O-N 3.09Å
47	V	86.9	Confident	79.8	Confident	21 Å²	21	67.1 Å²	67.1	13%	0.127	35%	0.354	C	S	.	.	H	α-helix	trans	-69.1	-42.1	174.8	176	0	0	0	0	111.7	I21 W31 D43 V44 G49 Q50 V51	I21-V47 HydrophobicContact CD1-CG1 3.7Å; W31-V47 HydrophobicContact CB-CG1 4.44Å; W31-V47 HydrophobicContact CD2-CB 4.33Å; W31-V47 HydrophobicContact CD2-CG1 3.92Å; W31-V47 HydrophobicContact CD2-CG2 3.97Å; W31-V47 HydrophobicContact CE3-CB 4.12Å; W31-V47 HydrophobicContact CE3-CG1 3.99Å; W31-V47 HydrophobicContact CE3-CG2 4.02Å; W31-V47 HydrophobicContact CG-CG1 4.11Å; W31-V47 HydrophobicContact CH2-CB 4.42Å; W31-V47 HydrophobicContact CH2-CG2 3.62Å; W31-V47 HydrophobicContact CZ2-CG2 3.59Å; W31-V47 HydrophobicContact CZ3-CB 4.16Å; W31-V47 HydrophobicContact CZ3-CG2 3.85Å; D43-V47 WeakPolarHBondContact O-CG2 3.4Å; D43-V47 PolarHBondContact O-N 3.05Å; D43-V47 VanDerWaalsContact O-N 3.1Å; V44-V47 PolarHBondContact O-N 3.06Å; V47-G49 PolarHBondContact O-N 2.8Å; V47-Q50 WeakPolarHBondContact O-CB 3.38Å; V47-Q50 PolarHBondContact O-N 2.91Å; V47-Q50 VanDerWaalsContact O-N 3.1Å; V47-V51 WeakPolarHBondContact O-CG2 3.34Å; V47-V51 PolarHBondContact O-N 2.8Å
48	I	86.3	Confident	80.5	Confident	0 Å²	0	67.6 Å²	67.6	0%	0	36%	0.355	C	S	.	.	H	α-helix	trans	-58.1	-40.7	172.6	-69.6	168.8	0	0	0	110.3	I21 V44 L45 Q50 V51 L52 T57 F60 I104 P106	I21-I48 HydrophobicContact CD1-CG1 4.17Å; I21-I48 HydrophobicContact CG2-CG1 4.16Å; V44-I48 HydrophobicContact CG1-CD1 3.84Å; V44-I48 HydrophobicContact CG1-CG1 4.35Å; V44-I48 WeakPolarHBondContact O-CB 3.44Å; V44-I48 VanDerWaalsContact O-CG1 3.24Å; V44-I48 WeakPolarHBondContact O-CG1 3.5Å; V44-I48 PolarHBondContact O-N 3.34Å; L45-I48 PolarHBondContact O-N 3.12Å; I48-Q50 VanDerWaalsContact C-N 3.3Å; I48-Q50 PolarHBondContact O-N 2.87Å; I48-V51 CarbonylContact O-C 3.3Å; I48-V51 PolarHBondContact O-N 3Å; I48-V51 VanDerWaalsContact O-N 3.17Å; I48-L52 HydrophobicContact CG2-CD1 4.25Å; I48-L52 WeakPolarHBondContact O-CB 3.44Å; I48-L52 PolarHBondContact O-N 2.94Å; I48-T57 HydrophobicContact CD1-CG2 4.41Å; I48-T57 HydrophobicContact CG2-CG2 3.84Å; I48-T57 WeakPolarHBondContact CG2-OG1 3.19Å; I48-F60 HydrophobicContact CD1-CB 3.91Å; I48-F60 HydrophobicContact CD1-CD1 3.92Å; I48-F60 HydrophobicContact CD1-CG 4.14Å; I48-I104 HydrophobicContact CD1-CD1 3.95Å; I48-I104 HydrophobicContact CG1-CD1 4.34Å; I48-P106 HydrophobicContact CD1-CG 4.26Å; I48-P106 HydrophobicContact CG1-CG 4.22Å; I48-P106 HydrophobicContact CG2-CB 3.73Å; I48-P106 HydrophobicContact CG2-CG 3.83Å
49	G	80.8	Confident	81.3	Confident	32 Å²	32	60.6 Å²	60.6	33%	0.33	32%	0.324	S	S	.	.	H	α-helix	trans	-63.3	-32.2	176.6	0	0	0	0	0	113.6	L45 D46 V47 L52 P53	L45-G49 PolarHBondContact O-N 3.37Å; D46-G49 PolarHBondContact O-N 2.88Å; V47-G49 PolarHBondContact O-N 2.8Å; G49-L52 CarbonylContact O-C 3.56Å; G49-P53 VanDerWaalsContact O-CA 3.3Å; G49-P53 WeakPolarHBondContact O-CA 3.35Å
50	Q	82	Confident	81.7	Confident	153 Å²	153	59.7 Å²	59.7	72%	0.715	32%	0.319	S	S	*	.	H	α-helix	trans	-71	-36.9	172.6	-67.3	171	30	0	0	112.1	D46 V47 I48	D46-Q50 WeakPolarHBondContact O-CG 3.32Å; D46-Q50 PolarHBondContact O-N 2.81Å; D46-Q50 VanDerWaalsContact O-N 3.09Å; V47-Q50 WeakPolarHBondContact O-CB 3.38Å; V47-Q50 PolarHBondContact O-N 2.91Å; V47-Q50 VanDerWaalsContact O-N 3.1Å; I48-Q50 VanDerWaalsContact C-N 3.3Å; I48-Q50 PolarHBondContact O-N 2.87Å
51	V	83.5	Confident	82	Confident	39 Å²	39	57 Å²	57	24%	0.236	31%	0.305	C	S	.	.	H	α-helix	trans	-78.8	-30.5	-179.8	178.2	0	0	0	0	112	I21 I23 V29 V47 I48 P53	I21-V51 HydrophobicContact CD1-CG2 4.4Å; I23-V51 HydrophobicContact CD1-CG1 3.3Å; I23-V51 HydrophobicContact CG1-CG1 3.64Å; V29-V51 HydrophobicContact CB-CG1 4.46Å; V29-V51 HydrophobicContact CG1-CG2 4.37Å; V29-V51 HydrophobicContact CG2-CG1 4.24Å; V47-V51 WeakPolarHBondContact O-CG2 3.34Å; V47-V51 PolarHBondContact O-N 2.8Å; I48-V51 CarbonylContact O-C 3.3Å; I48-V51 PolarHBondContact O-N 3Å; I48-V51 VanDerWaalsContact O-N 3.17Å; V51-P53 VanDerWaalsContact C-CD 3.5Å
52	L	79.9	Confident	82.2	Confident	29 Å²	29	57.2 Å²	57.2	15%	0.152	31%	0.305	C	S	.	.			trans	-126	68.3	179.8	-73	173.4	0	0	0	111	I23 I48 G49 E54 A55 P106	I23-L52 HydrophobicContact CG2-CD2 3.72Å; I48-L52 HydrophobicContact CG2-CD1 4.25Å; I48-L52 WeakPolarHBondContact O-CB 3.44Å; I48-L52 PolarHBondContact O-N 2.94Å; G49-L52 CarbonylContact O-C 3.56Å; L52-E54 PolarHBondContact O-N 2.97Å; L52-E54 VanDerWaalsContact O-N 3.13Å; L52-A55 HydrophobicContact CB-CB 3.96Å; L52-A55 PolarHBondContact O-N 2.97Å; L52-P106 HydrophobicContact CD1-CB 3.57Å; L52-P106 HydrophobicContact CD1-CG 3.84Å
53	P	71.9	Confident	82.3	Confident	110 Å²	110	53 Å²	53	71%	0.714	29%	0.293	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.4	-21.4	-173.8	24.2	-33.4	0	0	0	114.1	G49 V51	G49-P53 VanDerWaalsContact O-CA 3.3Å; G49-P53 WeakPolarHBondContact O-CA 3.35Å; V51-P53 VanDerWaalsContact C-CD 3.5Å
54	E	65.7	Low	82.1	Confident	189 Å²	189	51.9 Å²	51.9	88%	0.883	29%	0.287	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.1	-5.5	177.5	-58.5	-162.9	172.7	0	0	113.6	L52	L52-E54 PolarHBondContact O-N 2.97Å; L52-E54 VanDerWaalsContact O-N 3.13Å
55	A	64.8	Low	81.7	Confident	22 Å²	22	58.6 Å²	58.6	18%	0.182	32%	0.318	C	S	.	.			trans	-107.2	133.6	-179.1	0	0	0	0	0	111.8	L52 T57 A108	L52-A55 HydrophobicContact CB-CB 3.96Å; L52-A55 PolarHBondContact O-N 2.97Å; A55-T57 PolarHBondContact O-N 2.95Å; A55-A108 HydrophobicContact CB-CB 4.06Å
56	T	67.6	Low	81.2	Confident	71 Å²	71	63.8 Å²	63.8	44%	0.436	35%	0.346	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.8	87.8	167.6	45.3	0	0	0	0	109	C109	T56-C109 WeakPolarHBondContact O-CB 3.39Å; T56-C109 PolarHBondContact O-N 3.29Å
57	T	75.6	Confident	80.9	Confident	18 Å²	18	61.4 Å²	61.4	11%	0.11	34%	0.342	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-83.7	118.4	177.1	-53.2	0	0	0	0	109.7	L45 I48 A55 A59 P106	L45-T57 HydrophobicContact CD2-CG2 4.08Å; I48-T57 HydrophobicContact CD1-CG2 4.41Å; I48-T57 HydrophobicContact CG2-CG2 3.84Å; I48-T57 WeakPolarHBondContact CG2-OG1 3.19Å; A55-T57 PolarHBondContact O-N 2.95Å; T57-A59 WeakPolarHBondContact CG2-O 3.47Å; T57-P106 HydrophobicContact CG2-CB 4.23Å
58	T	82.5	Confident	80.6	Confident	91 Å²	91	65.2 Å²	65.2	56%	0.558	36%	0.361	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-113.2	-2.4	177.2	60.8	0	0	0	0	112.9
59	A	88.6	Confident	80.7	Confident	7 Å²	7	70.2 Å²	70.2	6%	0.058	38%	0.38	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-162.3	157.6	179.7	0	0	0	0	0	109.1	T57 T71 V72 R73 R107	T57-A59 WeakPolarHBondContact CG2-O 3.47Å; A59-T71 HydrophobicContact CB-CG2 3.92Å; A59-V72 WeakPolarHBondContact CA-O 3.45Å; A59-V72 WeakPolarHBondContact CB-O 3.48Å; A59-R73 HydrophobicContact CB-CG 3.97Å; A59-R107 WeakPolarHBondContact O-CB 3.34Å; A59-R107 PolarHBondContact O-N 3.5Å; A59-R107 VanDerWaalsContact O-N 3.12Å
60	F	91.9	Very high	80.9	Confident	0 Å²	0	71.7 Å²	71.7	0%	0	38%	0.38	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-135.3	165.3	171.3	59.3	-93.4	0	0	0	109.6	F41 V44 L45 I48 V72 M81 I104 F105	F41-F60 HydrophobicContact CD2-CD1 4.36Å; F41-F60 AromaticContact CD2-CE1 3.49Å; F41-F60 HydrophobicContact CD2-CE1 3.49Å; F41-F60 VanDerWaalsContact CD2-CE1 3.49Å; F41-F60 HydrophobicContact CD2-CZ 4.07Å; F41-F60 AromaticContact CE2-CD1 3.8Å; F41-F60 HydrophobicContact CE2-CD1 3.8Å; F41-F60 AromaticContact CE2-CE1 3.36Å; F41-F60 HydrophobicContact CE2-CE1 3.36Å; F41-F60 HydrophobicContact CE2-CZ 4.2Å; V44-F60 HydrophobicContact CB-CE1 3.86Å; V44-F60 HydrophobicContact CB-CZ 4.27Å; V44-F60 HydrophobicContact CG1-CD1 3.83Å; V44-F60 HydrophobicContact CG1-CE1 3.43Å; V44-F60 VanDerWaalsContact CG1-CE1 3.43Å; V44-F60 HydrophobicContact CG1-CE2 4.46Å; V44-F60 HydrophobicContact CG1-CG 4.49Å; V44-F60 HydrophobicContact CG1-CZ 3.79Å; L45-F60 HydrophobicContact CD2-CD1 4.19Å; I48-F60 HydrophobicContact CD1-CB 3.91Å; I48-F60 HydrophobicContact CD1-CD1 3.92Å; I48-F60 HydrophobicContact CD1-CG 4.14Å; F60-V72 HydrophobicContact CD2-CB 4.07Å; F60-V72 HydrophobicContact CD2-CG2 4.26Å; F60-V72 HydrophobicContact CE1-CB 4.35Å; F60-V72 HydrophobicContact CE1-CG1 4.24Å; F60-V72 HydrophobicContact CE2-CB 3.65Å; F60-V72 HydrophobicContact CE2-CG1 4Å; F60-V72 HydrophobicContact CE2-CG2 3.77Å; F60-V72 HydrophobicContact CZ-CB 3.81Å; F60-V72 HydrophobicContact CZ-CG1 3.68Å; F60-V72 HydrophobicContact CZ-CG2 4.32Å; F60-V72 PolarHBondContact N-O 2.77Å; F60-V72 PolarHBondContact O-N 3.12Å; F60-M81 HydrophobicContact CE2-CE 3.9Å; F60-M81 HydrophobicContact CE2-SD 3.84Å; F60-M81 HydrophobicContact CZ-CE 4.22Å; F60-I104 HydrophobicContact CD2-CB 3.91Å; F60-I104 HydrophobicContact CD2-CD1 4.21Å; F60-I104 HydrophobicContact CD2-CG2 3.94Å; F60-I104 HydrophobicContact CE2-CB 4.47Å; F60-I104 HydrophobicContact CE2-CG2 4.02Å; F60-I104 HydrophobicContact CG-CD1 4.35Å; F60-F105 CarbonylContact C-O 3.59Å; F60-F105 WeakPolarHBondContact CA-O 3.22Å
61	E	93.3	Very high	81.4	Confident	32 Å²	32	65.4 Å²	65.4	15%	0.15	35%	0.352	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-117.8	152.9	179.6	-71.6	163.4	-176.2	0	0	110.4	R69 I70 T71 I104 F105 R107	E61-R69 HydrophobicContact CB-CB 4.48Å; E61-I70 CarbonylContact C-O 3.31Å; E61-I70 WeakPolarHBondContact CA-O 3.44Å; E61-T71 HydrophobicContact CG-CG2 4.02Å; E61-T71 PolarHBondContact OE1-OG1 2.61Å; E61-I104 CarbonylContact O-C 3.6Å; E61-I104 VanDerWaalsContact O-CA 3.28Å; E61-I104 WeakPolarHBondContact O-CA 3.44Å; E61-F105 HydrophobicContact CB-CB 4.31Å; E61-F105 PolarHBondContact N-O 3.38Å; E61-F105 PolarHBondContact O-N 3.01Å; E61-R107 WeakPolarHBondContact OE1-CD 3.37Å; E61-R107 IonicContact OE1-CZ 3.41Å; E61-R107 IonicContact OE1-NE 3.14Å; E61-R107 IonicContact OE1-NH1 2.68Å; E61-R107 PolarHBondContact OE1-NH1 3.26Å
62	Y	93.1	Very high	81.6	Confident	27 Å²	27	63.6 Å²	63.6	11%	0.106	34%	0.341	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.7	167.6	165.3	74.6	-81.1	0	0	0	109.5	R69 I70 V72 M81 Y84	Y62-R69 CarbonylContact O-C 3.51Å; Y62-R69 WeakPolarHBondContact O-CA 3.4Å; Y62-I70 HydrophobicContact CD1-CB 3.94Å; Y62-I70 HydrophobicContact CD1-CG2 4.29Å; Y62-I70 WeakPolarHBondContact CD1-O 3.45Å; Y62-I70 HydrophobicContact CE1-CB 3.5Å; Y62-I70 HydrophobicContact CE1-CG1 4.4Å; Y62-I70 HydrophobicContact CE1-CG2 3.48Å; Y62-I70 VanDerWaalsContact CE1-CG2 3.48Å; Y62-I70 HydrophobicContact CE2-CB 4.37Å; Y62-I70 HydrophobicContact CE2-CG1 4.49Å; Y62-I70 PolarHBondContact N-O 2.85Å; Y62-I70 PolarHBondContact O-N 2.8Å; Y62-V72 HydrophobicContact CD1-CG2 3.76Å; Y62-V72 HydrophobicContact CE1-CG2 4.02Å; Y62-M81 HydrophobicContact CD1-CB 4.01Å; Y62-M81 HydrophobicContact CD1-CG 3.49Å; Y62-M81 VanDerWaalsContact CD1-CG 3.49Å; Y62-M81 HydrophobicContact CD1-SD 3.61Å; Y62-M81 HydrophobicContact CD2-CG 4Å; Y62-M81 HydrophobicContact CE1-CB 3.68Å; Y62-M81 HydrophobicContact CE1-CG 3.64Å; Y62-M81 HydrophobicContact CE1-SD 4.29Å; Y62-M81 HydrophobicContact CE2-CG 4.17Å; Y62-M81 HydrophobicContact CG-CG 3.67Å; Y62-M81 HydrophobicContact CG-SD 3.82Å; Y62-Y84 AromaticContact CE2-CD1 3.81Å; Y62-Y84 HydrophobicContact CE2-CD1 3.81Å; Y62-Y84 HydrophobicContact CE2-CE1 4.06Å
63	E	88.6	Confident	82.1	Confident	89 Å²	89	68.4 Å²	68.4	42%	0.416	36%	0.357	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-102	131.5	176.8	-151.9	164.1	128.8	0	0	109.2	D68 R69	E63-D68 WeakPolarHBondContact CA-O 3.48Å; E63-R69 IonicContact OE2-CZ 3.56Å; E63-R69 IonicContact OE2-NH1 2.79Å; E63-R69 PolarHBondContact OE2-NH1 3.44Å; E63-R69 IonicContact OE2-NH2 3.56Å; E63-R69 PolarHBondContact OE2-NH2 2.78Å
64	D	83.8	Confident	82.7	Confident	39 Å²	39	64.8 Å²	64.8	21%	0.209	33%	0.334	C	S	.	.			trans	-87.5	-173.4	169.8	67.8	14.1	0	0	0	112	D66 G67 D68 I70	D64-D66 PolarHBondContact O-N 3Å; D64-D66 PolarHBondContact OD1-N 3.28Å; D64-G67 PolarHBondContact O-N 3.3Å; D64-G67 PolarHBondContact OD1-N 2.9Å; D64-G67 VanDerWaalsContact OD1-N 3.12Å; D64-D68 PolarHBondContact N-O 3.39Å; D64-D68 PolarHBondContact OD1-N 3.26Å; D64-I70 HydrophobicContact CB-CG1 4.28Å
65	E	78.5	Confident	83.5	Confident	142 Å²	142	58.8 Å²	58.8	66%	0.664	31%	0.308	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.2	-28	-179.2	-94.5	159.7	-140.5	0	0	113.1	G67 Y84	E65-G67 VanDerWaalsContact C-N 3.32Å; E65-Y84 WeakPolarHBondContact CB-OH 3.47Å; E65-Y84 WeakPolarHBondContact CG-OH 3.32Å; E65-Y84 PolarHBondContact N-OH 3.2Å; E65-Y84 PolarHBondContact OE1-OH 3.01Å
66	D	76.2	Confident	84.4	Confident	144 Å²	144	64.2 Å²	64.2	77%	0.77	33%	0.33	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.1	-5.5	-179.7	-67.9	-53.5	0	0	0	112.3	D64	D64-D66 PolarHBondContact O-N 3Å; D64-D66 PolarHBondContact OD1-N 3.28Å
67	G	77.8	Confident	85.4	Confident	35 Å²	35	64.2 Å²	64.2	36%	0.361	33%	0.325	S	S	.	.			trans	88.3	8.4	-177.6	0	0	0	0	0	113.8	D64 E65	D64-G67 PolarHBondContact O-N 3.3Å; D64-G67 PolarHBondContact OD1-N 2.9Å; D64-G67 VanDerWaalsContact OD1-N 3.12Å; E65-G67 VanDerWaalsContact C-N 3.32Å
68	D	81.3	Confident	86	Confident	101 Å²	101	63.4 Å²	63.4	54%	0.54	32%	0.32	S	S	.	.			trans	-80.3	140.5	-176.8	-81.4	-28.9	0	0	0	111.8	E63 D64 I70	E63-D68 WeakPolarHBondContact CA-O 3.48Å; D64-D68 PolarHBondContact N-O 3.39Å; D64-D68 PolarHBondContact OD1-N 3.26Å; D68-I70 HydrophobicContact CB-CD1 4.31Å; D68-I70 PolarHBondContact O-N 3.37Å
69	R	87.1	Confident	86.2	Confident	104 Å²	104	65.9 Å²	65.9	39%	0.392	32%	0.323	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-83.2	96.3	179.2	-72.6	-81.8	178.7	-113.5	-12.2	110.3	E61 Y62 E63 F105	E61-R69 HydrophobicContact CB-CB 4.48Å; Y62-R69 CarbonylContact O-C 3.51Å; Y62-R69 WeakPolarHBondContact O-CA 3.4Å; E63-R69 IonicContact OE2-CZ 3.56Å; E63-R69 IonicContact OE2-NH1 2.79Å; E63-R69 PolarHBondContact OE2-NH1 3.44Å; E63-R69 IonicContact OE2-NH2 3.56Å; E63-R69 PolarHBondContact OE2-NH2 2.78Å; R69-F105 VanDerWaalsContact CZ-CZ 3.45Å; R69-F105 VanDerWaalsContact NH1-CD2 3.26Å
70	I	86.4	Confident	86	Confident	63 Å²	63	68.3 Å²	68.3	32%	0.323	34%	0.343	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-87.7	122.7	178.2	-51.9	-55.6	0	0	0	110	E61 Y62 D64 D68	E61-I70 CarbonylContact C-O 3.31Å; E61-I70 WeakPolarHBondContact CA-O 3.44Å; Y62-I70 HydrophobicContact CD1-CB 3.94Å; Y62-I70 HydrophobicContact CD1-CG2 4.29Å; Y62-I70 WeakPolarHBondContact CD1-O 3.45Å; Y62-I70 HydrophobicContact CE1-CB 3.5Å; Y62-I70 HydrophobicContact CE1-CG1 4.4Å; Y62-I70 HydrophobicContact CE1-CG2 3.48Å; Y62-I70 VanDerWaalsContact CE1-CG2 3.48Å; Y62-I70 HydrophobicContact CE2-CB 4.37Å; Y62-I70 HydrophobicContact CE2-CG1 4.49Å; Y62-I70 PolarHBondContact N-O 2.85Å; Y62-I70 PolarHBondContact O-N 2.8Å; D64-I70 HydrophobicContact CB-CG1 4.28Å; D68-I70 HydrophobicContact CB-CD1 4.31Å; D68-I70 PolarHBondContact O-N 3.37Å
71	T	91.5	Very high	86	Confident	21 Å²	21	68.4 Å²	68.4	13%	0.129	34%	0.344	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.4	133.4	-179.2	-42.5	0	0	0	0	112.6	A59 E61 R73 R107	A59-T71 HydrophobicContact CB-CG2 3.92Å; E61-T71 HydrophobicContact CG-CG2 4.02Å; E61-T71 PolarHBondContact OE1-OG1 2.61Å; T71-R73 VanDerWaalsContact CB-CZ 3.45Å; T71-R73 VanDerWaalsContact CB-NH2 3.27Å; T71-R73 HydrophobicContact CG2-CG 3.88Å; T71-R73 VanDerWaalsContact CG2-NH2 3.35Å; T71-R73 PolarHBondContact OG1-NH2 2.88Å; T71-R107 PolarHBondContact OG1-NH1 3.09Å
72	V	88.6	Confident	85.8	Confident	1 Å²	1	67.4 Å²	67.4	1%	0.006	34%	0.339	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-106.1	125.6	173.3	-173.6	0	0	0	0	109.9	F41 A59 F60 Y62 E77 M78 M81	F41-V72 HydrophobicContact CD2-CG1 3.88Å; F41-V72 HydrophobicContact CE2-CG1 4.01Å; F41-V72 WeakPolarHBondContact CE2-O 3.46Å; A59-V72 WeakPolarHBondContact CA-O 3.45Å; A59-V72 WeakPolarHBondContact CB-O 3.48Å; F60-V72 HydrophobicContact CD2-CB 4.07Å; F60-V72 HydrophobicContact CD2-CG2 4.26Å; F60-V72 HydrophobicContact CE1-CB 4.35Å; F60-V72 HydrophobicContact CE1-CG1 4.24Å; F60-V72 HydrophobicContact CE2-CB 3.65Å; F60-V72 HydrophobicContact CE2-CG1 4Å; F60-V72 HydrophobicContact CE2-CG2 3.77Å; F60-V72 HydrophobicContact CZ-CB 3.81Å; F60-V72 HydrophobicContact CZ-CG1 3.68Å; F60-V72 HydrophobicContact CZ-CG2 4.32Å; F60-V72 PolarHBondContact N-O 2.77Å; F60-V72 PolarHBondContact O-N 3.12Å; Y62-V72 HydrophobicContact CD1-CG2 3.76Å; Y62-V72 HydrophobicContact CE1-CG2 4.02Å; V72-E77 HydrophobicContact CG1-CB 4.04Å; V72-M78 HydrophobicContact CG1-CB 3.98Å; V72-M81 HydrophobicContact CG2-CB 4.33Å; V72-M81 HydrophobicContact CG2-SD 3.87Å
73	R	89	Confident	85.5	Confident	131 Å²	131	69.6 Å²	69.6	49%	0.494	36%	0.359	S	S	.	.			trans	-134.1	-1.4	-175.4	-51	-175	180	81.6	1.7	113.4	F41 A59 T71 E77	F41-R73 WeakPolarHBondContact CE1-O 3.48Å; A59-R73 HydrophobicContact CB-CG 3.97Å; T71-R73 VanDerWaalsContact CB-CZ 3.45Å; T71-R73 VanDerWaalsContact CB-NH2 3.27Å; T71-R73 HydrophobicContact CG2-CG 3.88Å; T71-R73 VanDerWaalsContact CG2-NH2 3.35Å; T71-R73 PolarHBondContact OG1-NH2 2.88Å; R73-E77 VanDerWaalsContact CA-OE2 3.27Å; R73-E77 WeakPolarHBondContact CA-OE2 3.48Å; R73-E77 VanDerWaalsContact CB-OE2 3.31Å; R73-E77 WeakPolarHBondContact CB-OE2 3.35Å; R73-E77 PolarHBondContact N-OE2 3.48Å
74	S	85.1	Confident	85.4	Confident	33 Å²	33	68.5 Å²	68.5	23%	0.231	35%	0.351	C	S	.	.	S	Bend	trans	-153.2	164.7	-172.9	58.4	0	0	0	0	112.3	E76 E77 M78	S74-E76 VanDerWaalsContact C-N 3.29Å; S74-E76 PolarHBondContact O-N 2.92Å; S74-E77 PolarHBondContact N-OE2 3.29Å; S74-E77 VanDerWaalsContact N-OE2 3.17Å; S74-E77 PolarHBondContact O-N 2.8Å; S74-E77 WeakPolarHBondContact OG-CB 3.42Å; S74-E77 VanDerWaalsContact OG-CG 3.31Å; S74-E77 WeakPolarHBondContact OG-CG 3.48Å; S74-E77 PolarHBondContact OG-N 3.16Å; S74-E77 PolarHBondContact OG-OE2 3.21Å; S74-M78 WeakPolarHBondContact O-CB 3.47Å; S74-M78 PolarHBondContact O-N 3.04Å
75	D	82.8	Confident	85.6	Confident	63 Å²	63	68 Å²	68	34%	0.337	35%	0.347	S	S	.	.	H	α-helix	trans	-65.8	-31.4	174.9	-71.8	-44.3	0	0	0	112	F41 M78 K79	F41-D75 VanDerWaalsContact CB-OD1 3.23Å; F41-D75 WeakPolarHBondContact CB-OD1 3.38Å; F41-D75 PolarHBondContact N-OD1 2.97Å; D75-M78 PolarHBondContact O-N 3.27Å; D75-K79 VanDerWaalsContact O-CG 3.31Å; D75-K79 WeakPolarHBondContact O-CG 3.1Å; D75-K79 PolarHBondContact O-N 3.23Å
76	E	83.1	Confident	86	Confident	137 Å²	137	62.7 Å²	62.7	64%	0.64	32%	0.32	S	S	*	.	H	α-helix	trans	-66	-48.7	175.1	-70.2	73.8	-162	0	0	112	S74 M78 K79 A80	S74-E76 VanDerWaalsContact C-N 3.29Å; S74-E76 PolarHBondContact O-N 2.92Å; E76-M78 VanDerWaalsContact C-N 3.25Å; E76-M78 PolarHBondContact O-N 2.79Å; E76-K79 PolarHBondContact O-N 2.83Å; E76-A80 PolarHBondContact O-N 2.81Å
77	E	88.1	Confident	86.3	Confident	71 Å²	71	58.9 Å²	58.9	33%	0.332	31%	0.305	S	S	.	.	H	α-helix	trans	-64.8	-33.9	176.1	-70.7	165	155.9	0	0	111.1	V72 R73 S74 A80 M81	V72-E77 HydrophobicContact CG1-CB 4.04Å; R73-E77 VanDerWaalsContact CA-OE2 3.27Å; R73-E77 WeakPolarHBondContact CA-OE2 3.48Å; R73-E77 VanDerWaalsContact CB-OE2 3.31Å; R73-E77 WeakPolarHBondContact CB-OE2 3.35Å; R73-E77 PolarHBondContact N-OE2 3.48Å; S74-E77 PolarHBondContact N-OE2 3.29Å; S74-E77 VanDerWaalsContact N-OE2 3.17Å; S74-E77 PolarHBondContact O-N 2.8Å; S74-E77 WeakPolarHBondContact OG-CB 3.42Å; S74-E77 VanDerWaalsContact OG-CG 3.31Å; S74-E77 WeakPolarHBondContact OG-CG 3.48Å; S74-E77 PolarHBondContact OG-N 3.16Å; S74-E77 PolarHBondContact OG-OE2 3.21Å; E77-A80 PolarHBondContact O-N 2.97Å; E77-M81 WeakPolarHBondContact O-CB 3.34Å; E77-M81 PolarHBondContact O-N 2.9Å
78	M	89.4	Confident	86.6	Confident	1 Å²	1	58.6 Å²	58.6	1%	0.005	30%	0.297	C	S	.	.	H	α-helix	trans	-65.6	-43	174	-176.4	174.6	-171.8	0	0	112.2	L39 F41 V44 V72 S74 D75 E76 A80 M81 L82	L39-M78 HydrophobicContact CB-CE 3.92Å; L39-M78 HydrophobicContact CD2-CE 3.35Å; L39-M78 HydrophobicContact CG-CE 3.37Å; L39-M78 WeakPolarHBondContact O-CE 2.94Å; F41-M78 WeakPolarHBondContact CA-SD 3.29Å; F41-M78 HydrophobicContact CB-SD 3.92Å; F41-M78 PolarHBondContact N-SD 3.36Å; V44-M78 HydrophobicContact CG2-CE 3.43Å; V44-M78 VanDerWaalsContact CG2-CE 3.43Å; V44-M78 HydrophobicContact CG2-SD 4.48Å; V72-M78 HydrophobicContact CG1-CB 3.98Å; S74-M78 WeakPolarHBondContact O-CB 3.47Å; S74-M78 PolarHBondContact O-N 3.04Å; D75-M78 PolarHBondContact O-N 3.27Å; E76-M78 VanDerWaalsContact C-N 3.25Å; E76-M78 PolarHBondContact O-N 2.79Å; M78-A80 VanDerWaalsContact C-N 3.3Å; M78-A80 PolarHBondContact O-N 3.47Å; M78-M81 HydrophobicContact CG-CE 4.22Å; M78-M81 PolarHBondContact O-N 2.85Å; M78-L82 HydrophobicContact CE-CD1 4.2Å; M78-L82 HydrophobicContact CG-CD1 4.1Å; M78-L82 HydrophobicContact CG-CG 4.37Å; M78-L82 WeakPolarHBondContact O-CB 3.33Å; M78-L82 WeakPolarHBondContact O-CG 3.34Å; M78-L82 PolarHBondContact O-N 2.96Å
79	K	86.1	Confident	86.7	Confident	142 Å²	142	54 Å²	54	62%	0.617	27%	0.272	S	S	*	.	H	α-helix	trans	-61.5	-39.7	174.3	-76.2	170.8	-175.3	172.5	0	111.6	D75 E76 S83	D75-K79 VanDerWaalsContact O-CG 3.31Å; D75-K79 WeakPolarHBondContact O-CG 3.1Å; D75-K79 PolarHBondContact O-N 3.23Å; E76-K79 PolarHBondContact O-N 2.83Å; K79-S83 VanDerWaalsContact O-CB 3.25Å; K79-S83 WeakPolarHBondContact O-CB 3.21Å; K79-S83 PolarHBondContact O-N 2.69Å
80	A	85.4	Confident	86.5	Confident	59 Å²	59	52.4 Å²	52.4	49%	0.488	27%	0.27	S	S	.	.	H	α-helix	trans	-63	-47.7	175.2	0	0	0	0	0	111.5	E76 E77 M78 L82 S83 Y84	E76-A80 PolarHBondContact O-N 2.81Å; E77-A80 PolarHBondContact O-N 2.97Å; M78-A80 VanDerWaalsContact C-N 3.3Å; M78-A80 PolarHBondContact O-N 3.47Å; A80-L82 PolarHBondContact O-N 2.93Å; A80-S83 PolarHBondContact O-N 3.34Å; A80-Y84 WeakPolarHBondContact O-CB 3.41Å; A80-Y84 PolarHBondContact O-N 2.91Å
81	M	92	Very high	86.3	Confident	1 Å²	1	55.1 Å²	55.1	1%	0.005	28%	0.281	C	S	.	.	H	α-helix	trans	-59.1	-47	175.4	177.8	-168	67	0	0	112.1	F60 Y62 V72 E77 M78 Y84 Y85 L102 I104	F60-M81 HydrophobicContact CE2-CE 3.9Å; F60-M81 HydrophobicContact CE2-SD 3.84Å; F60-M81 HydrophobicContact CZ-CE 4.22Å; Y62-M81 HydrophobicContact CD1-CB 4.01Å; Y62-M81 HydrophobicContact CD1-CG 3.49Å; Y62-M81 VanDerWaalsContact CD1-CG 3.49Å; Y62-M81 HydrophobicContact CD1-SD 3.61Å; Y62-M81 HydrophobicContact CD2-CG 4Å; Y62-M81 HydrophobicContact CE1-CB 3.68Å; Y62-M81 HydrophobicContact CE1-CG 3.64Å; Y62-M81 HydrophobicContact CE1-SD 4.29Å; Y62-M81 HydrophobicContact CE2-CG 4.17Å; Y62-M81 HydrophobicContact CG-CG 3.67Å; Y62-M81 HydrophobicContact CG-SD 3.82Å; V72-M81 HydrophobicContact CG2-CB 4.33Å; V72-M81 HydrophobicContact CG2-SD 3.87Å; E77-M81 WeakPolarHBondContact O-CB 3.34Å; E77-M81 PolarHBondContact O-N 2.9Å; M78-M81 HydrophobicContact CG-CE 4.22Å; M78-M81 PolarHBondContact O-N 2.85Å; M81-Y84 WeakPolarHBondContact O-CB 3.19Å; M81-Y84 PolarHBondContact O-N 2.84Å; M81-Y85 WeakPolarHBondContact O-CB 3.46Å; M81-Y85 PolarHBondContact O-N 2.87Å; M81-L102 HydrophobicContact CE-CD2 3.82Å; M81-L102 HydrophobicContact CG-CD1 4.41Å; M81-L102 HydrophobicContact SD-CD1 4.42Å; M81-L102 HydrophobicContact SD-CD2 4.22Å; M81-I104 HydrophobicContact SD-CG2 4.41Å
82	L	88.8	Confident	85.8	Confident	12 Å²	12	56.2 Å²	56.2	6%	0.063	29%	0.285	C	S	.	.	H	α-helix	trans	-64.6	-43.6	178.9	-72.2	174.8	0	0	0	111.1	L17 M78 A80 Y84 Y85 Y86 L102	L17-L82 HydrophobicContact CD2-CD2 3.74Å; M78-L82 HydrophobicContact CE-CD1 4.2Å; M78-L82 HydrophobicContact CG-CD1 4.1Å; M78-L82 HydrophobicContact CG-CG 4.37Å; M78-L82 WeakPolarHBondContact O-CB 3.33Å; M78-L82 WeakPolarHBondContact O-CG 3.34Å; M78-L82 PolarHBondContact O-N 2.96Å; A80-L82 PolarHBondContact O-N 2.93Å; L82-Y84 VanDerWaalsContact C-N 3.31Å; L82-Y84 PolarHBondContact O-N 3.41Å; L82-Y85 PolarHBondContact O-N 3.23Å; L82-Y86 HydrophobicContact CB-CD2 4.35Å; L82-Y86 HydrophobicContact CB-CE2 4.22Å; L82-Y86 WeakPolarHBondContact O-CB 3.36Å; L82-Y86 WeakPolarHBondContact O-CD2 3.41Å; L82-Y86 PolarHBondContact O-N 2.61Å; L82-L102 HydrophobicContact CD2-CD2 4.16Å
83	S	85.9	Confident	85.4	Confident	73 Å²	73	60 Å²	60	51%	0.51	30%	0.302	S	S	.	.	H	α-helix	trans	-58.8	-44.6	175.7	-172.3	0	0	0	0	111.4	K79 A80 Y86 S87	K79-S83 VanDerWaalsContact O-CB 3.25Å; K79-S83 WeakPolarHBondContact O-CB 3.21Å; K79-S83 PolarHBondContact O-N 2.69Å; A80-S83 PolarHBondContact O-N 3.34Å; S83-Y86 PolarHBondContact O-N 3.3Å; S83-S87 PolarHBondContact O-N 3.25Å; S83-S87 PolarHBondContact O-OG 3.41Å
84	Y	86.6	Confident	85	Confident	65 Å²	65	59.7 Å²	59.7	26%	0.255	32%	0.315	S	S	.	.	H	α-helix	trans	-59.9	-53.3	175.9	170.4	-102.1	0	0	0	111.3	Y62 E65 A80 M81 L82 Y86 S87 T88	Y62-Y84 AromaticContact CE2-CD1 3.81Å; Y62-Y84 HydrophobicContact CE2-CD1 3.81Å; Y62-Y84 HydrophobicContact CE2-CE1 4.06Å; E65-Y84 WeakPolarHBondContact CB-OH 3.47Å; E65-Y84 WeakPolarHBondContact CG-OH 3.32Å; E65-Y84 PolarHBondContact N-OH 3.2Å; E65-Y84 PolarHBondContact OE1-OH 3.01Å; A80-Y84 WeakPolarHBondContact O-CB 3.41Å; A80-Y84 PolarHBondContact O-N 2.91Å; M81-Y84 WeakPolarHBondContact O-CB 3.19Å; M81-Y84 PolarHBondContact O-N 2.84Å; L82-Y84 VanDerWaalsContact C-N 3.31Å; L82-Y84 PolarHBondContact O-N 3.41Å; Y84-Y86 VanDerWaalsContact C-N 3.33Å; Y84-Y86 PolarHBondContact O-N 3.16Å; Y84-S87 WeakPolarHBondContact O-CB 3.49Å; Y84-S87 PolarHBondContact O-N 3.37Å; Y84-S87 VanDerWaalsContact O-N 3.09Å; Y84-T88 PolarHBondContact O-N 3.18Å; Y84-T88 PolarHBondContact O-OG1 3.39Å; Y84-T88 VanDerWaalsContact O-OG1 3.12Å
85	Y	87.9	Confident	84.8	Confident	30 Å²	30	63.4 Å²	63.4	12%	0.118	33%	0.332	C	S	.	.	H	α-helix	trans	-55.7	-46.2	178.1	174.2	-99.6	0	0	0	112.2	L17 M81 L82 S87 T88 V89 E100 L102	L17-Y85 HydrophobicContact CD1-CD1 3.85Å; L17-Y85 HydrophobicContact CD1-CE1 3.32Å; M81-Y85 WeakPolarHBondContact O-CB 3.46Å; M81-Y85 PolarHBondContact O-N 2.87Å; L82-Y85 PolarHBondContact O-N 3.23Å; Y85-S87 VanDerWaalsContact C-N 3.33Å; Y85-S87 PolarHBondContact O-N 3.15Å; Y85-T88 PolarHBondContact O-N 3.18Å; Y85-V89 HydrophobicContact CD1-CG2 4.13Å; Y85-V89 HydrophobicContact CD2-CG2 4.25Å; Y85-V89 HydrophobicContact CE1-CG2 3.7Å; Y85-V89 HydrophobicContact CE2-CG2 3.85Å; Y85-V89 HydrophobicContact CG-CG2 4.39Å; Y85-V89 VanDerWaalsContact O-CG2 3.28Å; Y85-V89 WeakPolarHBondContact O-CG2 3.38Å; Y85-V89 PolarHBondContact O-N 3.42Å; Y85-E100 WeakPolarHBondContact CE2-O 3.38Å; Y85-E100 PolarHBondContact OH-O 2.82Å; Y85-E100 VanDerWaalsContact OH-O 3.09Å; Y85-L102 HydrophobicContact CD1-CB 4.47Å; Y85-L102 HydrophobicContact CD2-CB 3.74Å; Y85-L102 HydrophobicContact CD2-CD1 3.7Å; Y85-L102 HydrophobicContact CD2-CG 4.24Å; Y85-L102 HydrophobicContact CE1-CB 4.36Å; Y85-L102 HydrophobicContact CE2-CB 3.6Å; Y85-L102 HydrophobicContact CE2-CD1 4.4Å; Y85-L102 HydrophobicContact CG-CB 4.16Å; Y85-L102 HydrophobicContact CG-CD1 4Å; Y85-L102 HydrophobicContact CG-CG 4.46Å
86	Y	85.9	Confident	84.6	Confident	29 Å²	29	63.9 Å²	63.9	11%	0.114	35%	0.352	C	S	.	.	H	α-helix	trans	-64.4	-35.9	178.7	-77.1	-56.2	0	0	0	112.9	M12 L82 S83 Y84 M90	M12-Y86 HydrophobicContact CE-CD1 3.73Å; M12-Y86 HydrophobicContact CE-CG 3.96Å; M12-Y86 HydrophobicContact SD-CD1 3.85Å; M12-Y86 HydrophobicContact SD-CE1 4.24Å; L82-Y86 HydrophobicContact CB-CD2 4.35Å; L82-Y86 HydrophobicContact CB-CE2 4.22Å; L82-Y86 WeakPolarHBondContact O-CB 3.36Å; L82-Y86 WeakPolarHBondContact O-CD2 3.41Å; L82-Y86 PolarHBondContact O-N 2.61Å; S83-Y86 PolarHBondContact O-N 3.3Å; Y84-Y86 VanDerWaalsContact C-N 3.33Å; Y84-Y86 PolarHBondContact O-N 3.16Å; Y86-M90 WeakPolarHBondContact O-CG 3.28Å; Y86-M90 PolarHBondContact O-N 2.98Å; Y86-M90 VanDerWaalsContact O-N 3.08Å
87	S	83.8	Confident	84.5	Confident	65 Å²	65	62.8 Å²	62.8	46%	0.455	35%	0.347	S	S	.	.	H	α-helix	trans	-62.4	-48	172.3	-70.8	0	0	0	0	111.4	S83 Y84 Y85 V89 M90 E91	S83-S87 PolarHBondContact O-N 3.25Å; S83-S87 PolarHBondContact O-OG 3.41Å; Y84-S87 WeakPolarHBondContact O-CB 3.49Å; Y84-S87 PolarHBondContact O-N 3.37Å; Y84-S87 VanDerWaalsContact O-N 3.09Å; Y85-S87 VanDerWaalsContact C-N 3.33Å; Y85-S87 PolarHBondContact O-N 3.15Å; S87-V89 PolarHBondContact O-N 3.47Å; S87-M90 PolarHBondContact O-N 2.84Å; S87-E91 PolarHBondContact O-N 3.27Å; S87-E91 VanDerWaalsContact O-N 3.14Å
88	T	83.6	Confident	84	Confident	29 Å²	29	66.8 Å²	66.8	18%	0.178	37%	0.37	C	S	.	.	H	α-helix	trans	-61.2	-43	177.6	-48	0	0	0	0	111.9	Y84 Y85 M90 E91 Q92	Y84-T88 PolarHBondContact O-N 3.18Å; Y84-T88 PolarHBondContact O-OG1 3.39Å; Y84-T88 VanDerWaalsContact O-OG1 3.12Å; Y85-T88 PolarHBondContact O-N 3.18Å; T88-M90 VanDerWaalsContact C-N 3.33Å; T88-M90 PolarHBondContact O-N 3.29Å; T88-E91 PolarHBondContact O-N 3.21Å; T88-Q92 WeakPolarHBondContact O-CG 3.28Å; T88-Q92 PolarHBondContact O-N 3.25Å
89	V	83.8	Confident	83.6	Confident	4 Å²	4	70 Å²	70	2%	0.024	39%	0.386	C	S	.	.	H	α-helix	trans	-62.2	-39.8	177.6	170.1	0	0	0	0	111.7	Y85 S87 Q92 Q93 I99	Y85-V89 HydrophobicContact CD1-CG2 4.13Å; Y85-V89 HydrophobicContact CD2-CG2 4.25Å; Y85-V89 HydrophobicContact CE1-CG2 3.7Å; Y85-V89 HydrophobicContact CE2-CG2 3.85Å; Y85-V89 HydrophobicContact CG-CG2 4.39Å; Y85-V89 VanDerWaalsContact O-CG2 3.28Å; Y85-V89 WeakPolarHBondContact O-CG2 3.38Å; Y85-V89 PolarHBondContact O-N 3.42Å; S87-V89 PolarHBondContact O-N 3.47Å; V89-Q92 PolarHBondContact O-N 3.31Å; V89-Q93 HydrophobicContact CG1-CG 4.44Å; V89-Q93 WeakPolarHBondContact O-CB 3.45Å; V89-Q93 WeakPolarHBondContact O-CG 3.25Å; V89-Q93 PolarHBondContact O-N 3.37Å; V89-I99 HydrophobicContact CG1-CD1 4.02Å; V89-I99 HydrophobicContact CG1-CG1 4.17Å; V89-I99 HydrophobicContact CG1-CG2 3.92Å; V89-I99 HydrophobicContact CG2-CG2 3.87Å
90	M	82.6	Confident	83.5	Confident	70 Å²	70	68.7 Å²	68.7	35%	0.345	38%	0.383	S	S	.	.	H	α-helix	trans	-63.9	-42.4	177.4	-74	-69.9	133.2	0	0	111.5	M12 Y86 S87 T88 Q93 V94	M12-M90 HydrophobicContact CE-CE 3.27Å; M12-M90 HydrophobicContact CE-CG 3.75Å; M12-M90 HydrophobicContact CE-SD 4.07Å; M12-M90 HydrophobicContact SD-CE 3.59Å; M12-M90 VanDerWaalsContact SD-CE 3.59Å; Y86-M90 WeakPolarHBondContact O-CG 3.28Å; Y86-M90 PolarHBondContact O-N 2.98Å; Y86-M90 VanDerWaalsContact O-N 3.08Å; S87-M90 PolarHBondContact O-N 2.84Å; T88-M90 VanDerWaalsContact C-N 3.33Å; T88-M90 PolarHBondContact O-N 3.29Å; M90-Q93 PolarHBondContact O-N 3.2Å; M90-V94 WeakPolarHBondContact O-CG2 3.33Å; M90-V94 PolarHBondContact O-N 3.37Å; M90-V94 VanDerWaalsContact O-N 3.09Å
91	E	82.2	Confident	83.7	Confident	121 Å²	121	67.2 Å²	67.2	57%	0.565	37%	0.368	S	S	*	.	H	α-helix	trans	-65.2	-42.5	175.8	-69.2	-177.1	-171.9	0	0	112.2	S87 T88 Q93 V94 N95	S87-E91 PolarHBondContact O-N 3.27Å; S87-E91 VanDerWaalsContact O-N 3.14Å; T88-E91 PolarHBondContact O-N 3.21Å; E91-Q93 PolarHBondContact O-N 3.47Å; E91-V94 PolarHBondContact O-N 3.31Å; E91-N95 WeakPolarHBondContact O-CB 3.46Å; E91-N95 PolarHBondContact O-N 3.17Å; E91-N95 PolarHBondContact O-ND2 3.09Å
92	Q	81.3	Confident	83.7	Confident	43 Å²	43	67.6 Å²	67.6	20%	0.201	37%	0.37	C	S	.	.	H	α-helix	trans	-61.9	-40.9	175.6	-72.8	177.9	-6.6	0	0	112.1	T88 V89 N95 G96 Q97	T88-Q92 WeakPolarHBondContact O-CG 3.28Å; T88-Q92 PolarHBondContact O-N 3.25Å; V89-Q92 PolarHBondContact O-N 3.31Å; Q92-N95 CarbonylContact O-C 3.52Å; Q92-N95 PolarHBondContact O-N 3.38Å; Q92-G96 PolarHBondContact O-N 3.26Å; Q92-G96 VanDerWaalsContact O-N 3.1Å; Q92-Q97 HydrophobicContact CB-CB 4.09Å; Q92-Q97 HydrophobicContact CG-CB 4.42Å; Q92-Q97 PolarHBondContact O-N 3.1Å
93	Q	80.5	Confident	83.8	Confident	80 Å²	80	69.3 Å²	69.3	37%	0.374	38%	0.378	S	S	.	.	H	α-helix	trans	-63.6	-43.3	176.3	-79.5	-178.4	-11	0	0	112.3	V89 M90 E91 N95 G96 I99	V89-Q93 HydrophobicContact CG1-CG 4.44Å; V89-Q93 WeakPolarHBondContact O-CB 3.45Å; V89-Q93 WeakPolarHBondContact O-CG 3.25Å; V89-Q93 PolarHBondContact O-N 3.37Å; M90-Q93 PolarHBondContact O-N 3.2Å; E91-Q93 PolarHBondContact O-N 3.47Å; Q93-N95 PolarHBondContact O-N 3.27Å; Q93-G96 PolarHBondContact O-N 2.65Å; Q93-I99 HydrophobicContact CG-CD1 3.67Å; Q93-I99 HydrophobicContact CG-CG1 4.11Å
94	V	80.3	Confident	84.2	Confident	126 Å²	126	65.9 Å²	65.9	76%	0.764	35%	0.354	S	S	*	.	H	α-helix	trans	-61.9	-36.3	176.2	171.2	0	0	0	0	111.1	M90 E91 G96	M90-V94 WeakPolarHBondContact O-CG2 3.33Å; M90-V94 PolarHBondContact O-N 3.37Å; M90-V94 VanDerWaalsContact O-N 3.09Å; E91-V94 PolarHBondContact O-N 3.31Å; V94-G96 VanDerWaalsContact C-N 3.31Å; V94-G96 PolarHBondContact O-N 3Å
95	N	79.8	Confident	84.4	Confident	110 Å²	110	64.8 Å²	64.8	59%	0.588	35%	0.35	S	S	*	.	T	Hydrogen-bonded Turn	trans	-86.4	4.4	179.9	-66.5	-25.1	0	0	0	114.1	E91 Q92 Q93 Q97	E91-N95 WeakPolarHBondContact O-CB 3.46Å; E91-N95 PolarHBondContact O-N 3.17Å; E91-N95 PolarHBondContact O-ND2 3.09Å; Q92-N95 CarbonylContact O-C 3.52Å; Q92-N95 PolarHBondContact O-N 3.38Å; Q93-N95 PolarHBondContact O-N 3.27Å; N95-Q97 HydrophobicContact CB-CG 4.22Å; N95-Q97 PolarHBondContact O-N 3.4Å
96	G	79.5	Confident	84.5	Confident	73 Å²	73	64 Å²	64	75%	0.753	35%	0.348	S	S	*	.	T	Hydrogen-bonded Turn	trans	66.3	22.2	179.9	0	0	0	0	0	114.4	Q92 Q93 V94	Q92-G96 PolarHBondContact O-N 3.26Å; Q92-G96 VanDerWaalsContact O-N 3.1Å; Q93-G96 PolarHBondContact O-N 2.65Å; V94-G96 VanDerWaalsContact C-N 3.31Å; V94-G96 PolarHBondContact O-N 3Å
97	Q	80.6	Confident	84.3	Confident	114 Å²	114	68.4 Å²	68.4	53%	0.533	37%	0.365	S	S	.	.	P	Polyproline II helix	trans	-84.5	155.1	179.8	-67.1	-178.8	-17.7	0	0	111.5	Q92 N95	Q92-Q97 HydrophobicContact CB-CB 4.09Å; Q92-Q97 HydrophobicContact CG-CB 4.42Å; Q92-Q97 PolarHBondContact O-N 3.1Å; N95-Q97 HydrophobicContact CB-CG 4.22Å; N95-Q97 PolarHBondContact O-N 3.4Å
98	L	78.3	Confident	83.2	Confident	155 Å²	155	68.1 Å²	68.1	81%	0.812	37%	0.367	S	S	*	.	P	Polyproline II helix	trans	-70	131.2	175.3	-158.8	91.2	0	0	0	109.3	E100	L98-E100 PolarHBondContact O-N 3.25Å
99	I	81.8	Confident	81.7	Confident	69 Å²	69	69.6 Å²	69.6	35%	0.354	38%	0.378	S	S	.	.	P	Polyproline II helix	trans	-77.8	118.3	178	-58.2	166.8	0	0	0	108.8	V89 Q93	V89-I99 HydrophobicContact CG1-CD1 4.02Å; V89-I99 HydrophobicContact CG1-CG1 4.17Å; V89-I99 HydrophobicContact CG1-CG2 3.92Å; V89-I99 HydrophobicContact CG2-CG2 3.87Å; Q93-I99 HydrophobicContact CG-CD1 3.67Å; Q93-I99 HydrophobicContact CG-CG1 4.11Å
100	E	83.9	Confident	79.8	Confident	115 Å²	115	78.6 Å²	78.6	54%	0.537	42%	0.416	S	S	.	.	P	Polyproline II helix	trans	-84.7	142.4	173.5	-65.5	-154.8	163.1	0	0	111.8	Y85 L98	Y85-E100 WeakPolarHBondContact CE2-O 3.38Å; Y85-E100 PolarHBondContact OH-O 2.82Å; Y85-E100 VanDerWaalsContact OH-O 3.09Å; L98-E100 PolarHBondContact O-N 3.25Å
101	P	88.8	Confident	77.6	Confident	27 Å²	27	80.1 Å²	80.1	18%	0.175	43%	0.432	C	S	.	.	P	Polyproline II helix	trans	-59.1	145.9	172	-24.5	34.8	0	0	0	112.5	V18 R20 Q103	V18-P101 HydrophobicContact CB-CB 4.13Å; V18-P101 HydrophobicContact CB-CG 4.46Å; V18-P101 HydrophobicContact CG1-CB 3.97Å; V18-P101 HydrophobicContact CG1-CG 4.21Å; V18-P101 WeakPolarHBondContact O-CA 3.43Å; V18-P101 WeakPolarHBondContact O-CB 3.43Å; R20-P101 HydrophobicContact CB-CB 4.02Å; P101-Q103 WeakPolarHBondContact O-CG 3.42Å; P101-Q103 PolarHBondContact O-N 2.96Å; P101-Q103 VanDerWaalsContact O-N 3.1Å
102	L	90.9	Very high	75.4	Confident	9 Å²	9	78.2 Å²	78.2	5%	0.047	43%	0.43	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-61.9	114.1	174.6	175	64	0	0	0	109.8	L17 V18 I19 R20 M81 L82 Y85 I104	L17-L102 HydrophobicContact CD1-CB 4.32Å; V18-L102 PolarHBondContact O-N 3.43Å; I19-L102 CarbonylContact C-O 3.55Å; I19-L102 WeakPolarHBondContact CA-O 3.08Å; I19-L102 HydrophobicContact CG1-CD2 4.4Å; R20-L102 PolarHBondContact N-O 3.44Å; M81-L102 HydrophobicContact CE-CD2 3.82Å; M81-L102 HydrophobicContact CG-CD1 4.41Å; M81-L102 HydrophobicContact SD-CD1 4.42Å; M81-L102 HydrophobicContact SD-CD2 4.22Å; L82-L102 HydrophobicContact CD2-CD2 4.16Å; Y85-L102 HydrophobicContact CD1-CB 4.47Å; Y85-L102 HydrophobicContact CD2-CB 3.74Å; Y85-L102 HydrophobicContact CD2-CD1 3.7Å; Y85-L102 HydrophobicContact CD2-CG 4.24Å; Y85-L102 HydrophobicContact CE1-CB 4.36Å; Y85-L102 HydrophobicContact CE2-CB 3.6Å; Y85-L102 HydrophobicContact CE2-CD1 4.4Å; Y85-L102 HydrophobicContact CG-CB 4.16Å; Y85-L102 HydrophobicContact CG-CD1 4Å; Y85-L102 HydrophobicContact CG-CG 4.46Å; L102-I104 HydrophobicContact CG-CG2 4.29Å
103	Q	92.4	Very high	73.4	Confident	49 Å²	49	78.5 Å²	78.5	23%	0.229	44%	0.444	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-89	126	-177.7	-53.5	-167.7	27.7	0	0	110.6	R20 P101 F105	R20-Q103 HydrophobicContact CB-CG 4.45Å; R20-Q103 WeakPolarHBondContact O-CA 3.12Å; P101-Q103 WeakPolarHBondContact O-CG 3.42Å; P101-Q103 PolarHBondContact O-N 2.96Å; P101-Q103 VanDerWaalsContact O-N 3.1Å; Q103-F105 HydrophobicContact CB-CE2 4.02Å; Q103-F105 HydrophobicContact CB-CZ 4.44Å
104	I	93.8	Very high	71.4	Confident	1 Å²	1	83.6 Å²	83.6	1%	0.005	47%	0.468	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.3	148.9	174.3	70.5	171.1	0	0	0	111.9	I19 R20 I21 K22 V44 I48 F60 E61 M81 L102	I19-I104 HydrophobicContact CG2-CD1 3.65Å; I19-I104 HydrophobicContact CG2-CG1 3.76Å; I19-I104 HydrophobicContact CG2-CG2 4.13Å; R20-I104 PolarHBondContact O-N 3.46Å; I21-I104 HydrophobicContact CB-CG1 4.36Å; I21-I104 HydrophobicContact CG1-CD1 4.02Å; I21-I104 HydrophobicContact CG1-CG1 4.02Å; I21-I104 HydrophobicContact CG2-CG1 4.44Å; K22-I104 WeakPolarHBondContact CB-O 3.42Å; K22-I104 PolarHBondContact N-O 3.32Å; V44-I104 HydrophobicContact CG1-CD1 3.5Å; I48-I104 HydrophobicContact CD1-CD1 3.95Å; I48-I104 HydrophobicContact CG1-CD1 4.34Å; F60-I104 HydrophobicContact CD2-CB 3.91Å; F60-I104 HydrophobicContact CD2-CD1 4.21Å; F60-I104 HydrophobicContact CD2-CG2 3.94Å; F60-I104 HydrophobicContact CE2-CB 4.47Å; F60-I104 HydrophobicContact CE2-CG2 4.02Å; F60-I104 HydrophobicContact CG-CD1 4.35Å; E61-I104 CarbonylContact O-C 3.6Å; E61-I104 VanDerWaalsContact O-CA 3.28Å; E61-I104 WeakPolarHBondContact O-CA 3.44Å; M81-I104 HydrophobicContact SD-CG2 4.41Å; L102-I104 HydrophobicContact CG-CG2 4.29Å
105	F	91.9	Very high	69.4	Low	41 Å²	41	86.1 Å²	86.1	18%	0.18	46%	0.463	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-123	103.3	-173.3	-60.4	-99.7	0	0	0	108.4	K22 F60 E61 R69 Q103 R107	K22-F105 HydrophobicContact CB-CD1 3.65Å; K22-F105 HydrophobicContact CB-CE1 3.78Å; K22-F105 HydrophobicContact CB-CG 4.27Å; K22-F105 HydrophobicContact CB-CZ 4.45Å; K22-F105 HydrophobicContact CD-CE1 4.27Å; K22-F105 HydrophobicContact CG-CD1 3.92Å; K22-F105 HydrophobicContact CG-CE1 3.55Å; K22-F105 HydrophobicContact CG-CE2 4.36Å; K22-F105 HydrophobicContact CG-CG 4.5Å; K22-F105 HydrophobicContact CG-CZ 3.79Å; F60-F105 CarbonylContact C-O 3.59Å; F60-F105 WeakPolarHBondContact CA-O 3.22Å; E61-F105 HydrophobicContact CB-CB 4.31Å; E61-F105 PolarHBondContact N-O 3.38Å; E61-F105 PolarHBondContact O-N 3.01Å; R69-F105 VanDerWaalsContact CZ-CZ 3.45Å; R69-F105 VanDerWaalsContact NH1-CD2 3.26Å; Q103-F105 HydrophobicContact CB-CE2 4.02Å; Q103-F105 HydrophobicContact CB-CZ 4.44Å; F105-R107 PolarHBondContact O-N 3.41Å
106	P	88.7	Confident	67.6	Low	13 Å²	13	84.6 Å²	84.6	8%	0.084	46%	0.455	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-58.3	131.9	176.5	-27	38	0	0	0	112	I21 K22 I48 L52 T57 A108	I21-P106 HydrophobicContact CG2-CG 3.57Å; K22-P106 WeakPolarHBondContact O-CD 3.4Å; I48-P106 HydrophobicContact CD1-CG 4.26Å; I48-P106 HydrophobicContact CG1-CG 4.22Å; I48-P106 HydrophobicContact CG2-CB 3.73Å; I48-P106 HydrophobicContact CG2-CG 3.83Å; L52-P106 HydrophobicContact CD1-CB 3.57Å; L52-P106 HydrophobicContact CD1-CG 3.84Å; T57-P106 HydrophobicContact CG2-CB 4.23Å; P106-A108 PolarHBondContact O-N 3.13Å
107	R	81.8	Confident	65.7	Low	122 Å²	122	88.1 Å²	88.1	46%	0.46	46%	0.456	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-95.1	93.3	174.3	-156.7	169.8	-179.3	168	-4.1	109.5	A59 E61 T71 F105 C109	A59-R107 WeakPolarHBondContact O-CB 3.34Å; A59-R107 PolarHBondContact O-N 3.5Å; A59-R107 VanDerWaalsContact O-N 3.12Å; E61-R107 WeakPolarHBondContact OE1-CD 3.37Å; E61-R107 IonicContact OE1-CZ 3.41Å; E61-R107 IonicContact OE1-NE 3.14Å; E61-R107 IonicContact OE1-NH1 2.68Å; E61-R107 PolarHBondContact OE1-NH1 3.26Å; T71-R107 PolarHBondContact OG1-NH1 3.09Å; F105-R107 PolarHBondContact O-N 3.41Å; R107-C109 PolarHBondContact O-N 2.88Å
108	A	60.8	Low	64	Low	60 Å²	60	89.7 Å²	89.7	50%	0.496	46%	0.463	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-64.8	116.8	177.3	0	0	0	0	0	110.6	A55 P106	A55-A108 HydrophobicContact CB-CB 4.06Å; P106-A108 PolarHBondContact O-N 3.13Å
109	C	52.7	Low	62.2	Low	60 Å²	60	84.6 Å²	84.6	41%	0.405	45%	0.447	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-79	135.7	160.9	-69.6	0	0	0	0	108.7	T56 R107	T56-C109 WeakPolarHBondContact O-CB 3.39Å; T56-C109 PolarHBondContact O-N 3.29Å; R107-C109 PolarHBondContact O-N 2.88Å
110	K	43.5	Very low	60.2	Low	192 Å²	192	86.4 Å²	86.4	84%	0.835	46%	0.457	S	S	*	.	P	Polyproline II helix	trans	-48.2	145	168.1	-74.3	-176.6	177.2	-177.7	0	109.7
111	P	36	Very low	57.9	Low	103 Å²	103	89.8 Å²	89.8	67%	0.669	47%	0.47	S	S	*	.	P	Polyproline II helix	trans	-51.7	144.3	179.2	20.9	-31.9	0	0	0	110.2	G113	P111-G113 PolarHBondContact O-N 2.93Å
112	P	37	Very low	55.3	Low	81 Å²	81	91.5 Å²	91.5	53%	0.526	48%	0.48	S	S	.	.	P	Polyproline II helix	trans	-58	118.6	-177.4	23.1	-31.4	0	0	0	108.7
113	G	38.8	Very low	52.6	Low	48 Å²	48	97.7 Å²	97.7	50%	0.495	51%	0.513	S	S	.	.	P	Polyproline II helix	trans	-51.4	149.9	175.3	0	0	0	0	0	111.3	P111 R115	P111-G113 PolarHBondContact O-N 2.93Å; G113-R115 PolarHBondContact O-N 3.21Å; G113-R115 VanDerWaalsContact O-N 3.11Å
114	E	38.8	Very low	49.9	Very low	187 Å²	187	101.2 Å²	101.2	87%	0.874	54%	0.538	S	S	*	.			trans	-41.5	117.6	-177.2	-67.3	-179.2	162.7	0	0	111.4
115	R	38.6	Very low	46.8	Very low	179 Å²	179	113.5 Å²	113.5	68%	0.675	58%	0.584	S	S	*	*			trans	-75.8	135	176.3	-61	-178.3	-175.6	-160.4	1.5	107.9	G113	G113-R115 PolarHBondContact O-N 3.21Å; G113-R115 VanDerWaalsContact O-N 3.11Å
116	N	42.2	Very low	43.7	Very low	78 Å²	78	116.2 Å²	116.2	42%	0.417	61%	0.614	S	S	.	*			trans	-69.7	171.6	167.5	68.2	14.2	0	0	0	110.9	H118 G119	N116-H118 PolarHBondContact O-N 3.38Å; N116-H118 PolarHBondContact OD1-N 2.95Å; N116-G119 PolarHBondContact O-N 3.08Å; N116-G119 PolarHBondContact OD1-N 3.25Å
117	I	39.6	Very low	40.8	Very low	148 Å²	148	119 Å²	119	76%	0.759	65%	0.646	S	S	*	*	T	Hydrogen-bonded Turn	trans	-56.4	-4.7	-177.7	61.2	169.5	0	0	0	115.6
118	H	43.9	Very low	38.7	Very low	147 Å²	147	119.3 Å²	119.3	68%	0.681	66%	0.663	S	S	*	*	T	Hydrogen-bonded Turn	trans	-120.4	9.9	-179.6	-60.8	-42.8	0	0	0	113.9	N116 L120	N116-H118 PolarHBondContact O-N 3.38Å; N116-H118 PolarHBondContact OD1-N 2.95Å; H118-L120 PolarHBondContact O-N 3.37Å
119	G	39.7	Very low	37	Very low	47 Å²	47	121.8 Å²	121.8	49%	0.485	68%	0.677	S	S	.	*			trans	74.2	22.5	166.5	0	0	0	0	0	116.2	N116	N116-G119 PolarHBondContact O-N 3.08Å; N116-G119 PolarHBondContact OD1-N 3.25Å
120	L	39.7	Very low	35.8	Very low	107 Å²	107	127.2 Å²	127.2	56%	0.56	70%	0.696	S	S	*	*	P	Polyproline II helix	trans	-101	147.7	175.1	-75.9	163.3	0	0	0	112.5	H118	H118-L120 PolarHBondContact O-N 3.37Å
121	K	35.8	Very low	34.9	Very low	186 Å²	186	125.5 Å²	125.5	81%	0.809	69%	0.691	S	S	*	*	P	Polyproline II helix	trans	-74.9	124.1	-178.7	-171.6	176.8	-178.2	176.4	0	110.9
122	V	35.8	Very low	34.4	Very low	63 Å²	63	125 Å²	125	38%	0.382	69%	0.69	S	S	.	*	P	Polyproline II helix	trans	-99.8	128.3	175.6	-178.4	0	0	0	0	109.5	T124	V122-T124 HydrophobicContact CG1-CG2 3.83Å
123	N	33.9	Very low	33.9	Very low	139 Å²	139	126.7 Å²	126.7	74%	0.743	70%	0.704	S	S	*	*			trans	-105.7	100.3	164.1	-98.9	-1.8	0	0	0	108
124	T	34.5	Very low	33.6	Very low	124 Å²	124	130.2 Å²	130.2	76%	0.761	72%	0.718	S	S	*	*			trans	-115.2	116.8	166.4	40.6	0	0	0	0	108.6	V122	V122-T124 HydrophobicContact CG1-CG2 3.83Å
125	R	28.5	Very low	33.1	Very low	259 Å²	259	126 Å²	126	98%	0.977	72%	0.715	S	S	*	*			trans	-110.1	118.4	160.5	-155.7	179.3	-171	179.5	1.9	106.5
126	A	28.3	Very low	32.5	Very low	98 Å²	98	124.3 Å²	124.3	81%	0.81	73%	0.725	S	S	*	*			trans	-134.9	136.8	162.1	0	0	0	0	0	108.3
127	G	27.7	Very low	32	Very low	72 Å²	72	125.5 Å²	125.5	74%	0.742	74%	0.739	S	S	*	*			trans	-72.7	-172.2	176.2	0	0	0	0	0	113.4
128	P	36.3	Very low	31.5	Very low	127 Å²	127	126.6 Å²	126.6	83%	0.825	75%	0.746	S	S	*	*			trans	-92.9	142.6	-145.7	35.3	-33.7	0	0	0	113.9
129	S	26.1	Very low	31.1	Very low	113 Å²	113	125 Å²	125	79%	0.79	75%	0.752	S	S	*	*			trans	-178.6	116.2	141.2	24.5	0	0	0	0	113.1
130	Q	26.5	Very low	30.8	Very low	173 Å²	173	130.9 Å²	130.9	81%	0.808	77%	0.771	S	S	*	*			trans	44.3	134.9	132.4	-68.4	-173.6	-15	0	0	124.4
131	H	26	Very low	30.6	Very low	156 Å²	156	130.1 Å²	130.1	72%	0.722	77%	0.773	S	S	*	*			trans	91.2	94.9	146.1	-73.2	-58.8	0	0	0	122.3
132	S	24.1	Very low	30.5	Very low	94 Å²	94	125.8 Å²	125.8	66%	0.657	77%	0.765	S	S	*	*				56	118.9	121.9	59.5	0	0	0	0	124.7
133	S	27.4	Very low	30.5	Very low	115 Å²	115	128.6 Å²	128.6	80%	0.804	78%	0.779	S	S	*	*			trans	87.7	160.4	138.6	-39.6	0	0	0	0	120
134	P	31.4	Very low	30.6	Very low	123 Å²	123	126.5 Å²	126.5	80%	0.799	77%	0.774	S	S	*	*				-126.2	159.7	-93.9	31.3	-10	0	0	0	116.8
135	A	28.4	Very low	30.7	Very low	99 Å²	99	126.4 Å²	126.4	82%	0.818	77%	0.769	S	S	*	*			trans	23.6	124.6	151.9	0	0	0	0	0	122.2
136	V	26.5	Very low	31.1	Very low	143 Å²	143	122.2 Å²	122.2	87%	0.867	76%	0.758	S	S	*	*			trans	-137.9	130.6	143.7	-173.9	0	0	0	0	109.3
137	S	32.2	Very low	31.4	Very low	102 Å²	102	125.2 Å²	125.2	71%	0.713	75%	0.753	S	S	*	*			trans	-75.6	139.4	178.7	51.7	0	0	0	0	112.8
138	D	28.2	Very low	32.3	Very low	172 Å²	172	124.6 Å²	124.6	92%	0.92	74%	0.736	S	S	*	*			trans	-145.5	127.9	151.8	-101	-27.7	0	0	0	111.3
139	S	36.9	Very low	32.6	Very low	113 Å²	113	121.6 Å²	121.6	79%	0.79	72%	0.719	S	S	*	*			trans	-107.7	123.3	-175	45.9	0	0	0	0	110.3
140	L	31.6	Very low	33.7	Very low	170 Å²	170	119.3 Å²	119.3	89%	0.89	71%	0.706	S	S	*	*			trans	-145.7	156.5	172.2	-87.9	173.7	0	0	0	110.9
141	P	35.8	Very low	34.8	Very low	92 Å²	92	116.9 Å²	116.9	60%	0.597	70%	0.695	S	S	*	*				-107.8	150.2	-122.3	27	-13.4	0	0	0	115.7	N143	P141-N143 PolarHBondContact O-N 2.92Å
142	S	33.9	Very low	35.6	Very low	94 Å²	94	111.9 Å²	111.9	66%	0.657	67%	0.674	S	S	*	*	T	Hydrogen-bonded Turn	trans	-66.4	12.8	-176.5	56.1	0	0	0	0	117.1
143	N	35.4	Very low	36.7	Very low	123 Å²	123	114.7 Å²	114.7	66%	0.658	67%	0.674	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.5	-16.7	-175.5	-91.8	-12.7	0	0	0	114.5	P141	P141-N143 PolarHBondContact O-N 2.92Å
144	S	36	Very low	37.6	Very low	94 Å²	94	115.9 Å²	115.9	66%	0.657	66%	0.664	S	S	*	*	H	α-helix	trans	-74.9	-27	-178.6	-41.8	0	0	0	0	113.2
145	L	37.4	Very low	38.4	Very low	122 Å²	122	112.9 Å²	112.9	64%	0.639	64%	0.641	S	S	*	*	H	α-helix	trans	-79.2	-27.3	-172.7	-71.1	161.2	0	0	0	113.6	S148	L145-S148 PolarHBondContact O-OG 3.04Å
146	K	35.9	Very low	39.2	Very low	171 Å²	171	112.7 Å²	112.7	74%	0.743	63%	0.626	S	S	*	*	H	α-helix	trans	-81.5	-28.3	178.4	-71.6	-178.5	179	177.8	0	112.7
147	K	36.4	Very low	40.1	Very low	162 Å²	162	109.7 Å²	109.7	70%	0.704	62%	0.616	S	S	*	*	H	α-helix	trans	-66.6	-43.8	174.8	-90.9	-176.3	172.8	-178.5	0	111.8	S149 A150 E151	K147-S149 VanDerWaalsContact C-N 3.34Å; K147-S149 PolarHBondContact O-N 3.44Å; K147-A150 PolarHBondContact O-N 3.37Å; K147-E151 WeakPolarHBondContact O-CB 3.38Å; K147-E151 PolarHBondContact O-N 2.89Å
148	S	45.9	Very low	40.6	Very low	58 Å²	58	109.8 Å²	109.8	41%	0.406	61%	0.609	S	S	.	*	H	α-helix	trans	-64.5	-34	-177.6	72.9	0	0	0	0	113.5	L145 L152	L145-S148 PolarHBondContact O-OG 3.04Å; S148-L152 VanDerWaalsContact O-CB 3.32Å; S148-L152 WeakPolarHBondContact O-CB 3.24Å; S148-L152 WeakPolarHBondContact O-CD1 3.33Å; S148-L152 PolarHBondContact O-N 3.34Å
149	S	43.5	Very low	41.5	Very low	65 Å²	65	103.5 Å²	103.5	46%	0.455	58%	0.584	S	S	.	*	H	α-helix	trans	-70.7	-37.3	179.2	-176.6	0	0	0	0	113.3	K147 K153	K147-S149 VanDerWaalsContact C-N 3.34Å; K147-S149 PolarHBondContact O-N 3.44Å; S149-K153 PolarHBondContact O-N 3.18Å
150	A	48.3	Very low	42.7	Very low	64 Å²	64	105.1 Å²	105.1	53%	0.529	58%	0.579	S	S	.	*	H	α-helix	trans	-73.2	-36.1	175.9	0	0	0	0	0	111.5	K147 K153 K154	K147-A150 PolarHBondContact O-N 3.37Å; A150-K153 PolarHBondContact O-N 2.58Å; A150-K154 WeakPolarHBondContact O-CB 3.5Å; A150-K154 PolarHBondContact O-N 3.37Å
151	E	50	Low	44.6	Very low	123 Å²	123	97.7 Å²	97.7	58%	0.575	54%	0.54	S	S	*	.	H	α-helix	trans	-68.8	-37.8	173.8	-145.7	154.8	-156.7	0	0	111.2	K147 K154 I155	K147-E151 WeakPolarHBondContact O-CB 3.38Å; K147-E151 PolarHBondContact O-N 2.89Å; E151-K154 CarbonylContact O-C 3.58Å; E151-K154 WeakPolarHBondContact O-CB 3.4Å; E151-K154 PolarHBondContact O-N 3.47Å; E151-I155 WeakPolarHBondContact O-CB 3.23Å; E151-I155 WeakPolarHBondContact O-CD1 3.37Å; E151-I155 WeakPolarHBondContact O-CG1 3.46Å; E151-I155 PolarHBondContact O-N 3.28Å
152	L	42.9	Very low	46.8	Very low	51 Å²	51	97.7 Å²	97.7	27%	0.267	54%	0.535	S	S	.	.	H	α-helix	trans	-60	-47.8	170.1	-112.3	86.7	0	0	0	112.3	S148 K154 I155 L156 E214	S148-L152 VanDerWaalsContact O-CB 3.32Å; S148-L152 WeakPolarHBondContact O-CB 3.24Å; S148-L152 WeakPolarHBondContact O-CD1 3.33Å; S148-L152 PolarHBondContact O-N 3.34Å; L152-K154 PolarHBondContact O-N 3.15Å; L152-I155 PolarHBondContact O-N 2.9Å; L152-I155 VanDerWaalsContact O-N 3.16Å; L152-L156 WeakPolarHBondContact O-CB 3.4Å; L152-L156 WeakPolarHBondContact O-CD1 3.33Å; L152-L156 WeakPolarHBondContact O-CG 3.39Å; L152-L156 PolarHBondContact O-N 2.86Å; L152-E214 WeakPolarHBondContact CD1-OE1 3.27Å; L152-E214 VanDerWaalsContact CD2-CD 3.47Å; L152-E214 WeakPolarHBondContact CD2-OE1 3.33Å; L152-E214 WeakPolarHBondContact CD2-OE2 3Å
153	K	47.3	Very low	49.2	Very low	152 Å²	152	97.4 Å²	97.4	66%	0.661	52%	0.523	S	S	*	.	H	α-helix	trans	-63.6	-32.1	176.3	-76.9	-177	179.6	-177.8	0	111.7	S149 A150 A157	S149-K153 PolarHBondContact O-N 3.18Å; A150-K153 PolarHBondContact O-N 2.58Å; K153-A157 WeakPolarHBondContact O-CB 3.3Å; K153-A157 PolarHBondContact O-N 2.87Å
154	K	46.7	Very low	51.6	Low	140 Å²	140	100.3 Å²	100.3	61%	0.609	53%	0.533	S	S	*	.	H	α-helix	trans	-72.5	-35.8	173.5	-136.7	176.4	-174.5	-178.6	0	111.9	A150 E151 L152 A157 N158	A150-K154 WeakPolarHBondContact O-CB 3.5Å; A150-K154 PolarHBondContact O-N 3.37Å; E151-K154 CarbonylContact O-C 3.58Å; E151-K154 WeakPolarHBondContact O-CB 3.4Å; E151-K154 PolarHBondContact O-N 3.47Å; L152-K154 PolarHBondContact O-N 3.15Å; K154-A157 CarbonylContact O-C 3.35Å; K154-A157 PolarHBondContact O-N 3.41Å; K154-N158 WeakPolarHBondContact O-CA 3.49Å; K154-N158 WeakPolarHBondContact O-CB 3.36Å; K154-N158 PolarHBondContact O-N 2.8Å
155	I	46.6	Very low	54.2	Low	61 Å²	61	97.9 Å²	97.9	31%	0.313	51%	0.513	S	S	.	.	H	α-helix	trans	-73	-38.4	175.8	-69.4	162.5	0	0	0	111.2	E151 L152 A157 N158 G159 Y217	E151-I155 WeakPolarHBondContact O-CB 3.23Å; E151-I155 WeakPolarHBondContact O-CD1 3.37Å; E151-I155 WeakPolarHBondContact O-CG1 3.46Å; E151-I155 PolarHBondContact O-N 3.28Å; L152-I155 PolarHBondContact O-N 2.9Å; L152-I155 VanDerWaalsContact O-N 3.16Å; I155-A157 PolarHBondContact O-N 3.33Å; I155-N158 CarbonylContact O-C 3.42Å; I155-N158 PolarHBondContact O-N 2.98Å; I155-G159 PolarHBondContact O-N 2.92Å; I155-Y217 HydrophobicContact CD1-CE1 4.21Å; I155-Y217 HydrophobicContact CG2-CD1 4.25Å; I155-Y217 HydrophobicContact CG2-CE1 3.78Å; I155-Y217 HydrophobicContact CG2-CE2 4.14Å
156	L	46.7	Very low	56.8	Low	94 Å²	94	92.6 Å²	92.6	49%	0.492	49%	0.485	S	S	.	.	H	α-helix	trans	-69.8	-19	172.2	-66.4	164.5	0	0	0	112.5	L152 M210	L152-L156 WeakPolarHBondContact O-CB 3.4Å; L152-L156 WeakPolarHBondContact O-CD1 3.33Å; L152-L156 WeakPolarHBondContact O-CG 3.39Å; L152-L156 PolarHBondContact O-N 2.86Å; L156-M210 HydrophobicContact CD2-CE 3.62Å
157	A	44.8	Very low	59.6	Low	80 Å²	80	92.2 Å²	92.2	66%	0.661	48%	0.479	S	S	*	.	H	α-helix	trans	-100.6	-12.4	169.9	0	0	0	0	0	114.1	K153 K154 I155	K153-A157 WeakPolarHBondContact O-CB 3.3Å; K153-A157 PolarHBondContact O-N 2.87Å; K154-A157 CarbonylContact O-C 3.35Å; K154-A157 PolarHBondContact O-N 3.41Å; I155-A157 PolarHBondContact O-N 3.33Å
158	N	41.8	Very low	62.4	Low	105 Å²	105	88.5 Å²	88.5	56%	0.561	46%	0.461	S	S	*	.	H	α-helix	trans	-117.7	7.9	-176.6	-78.3	-3.1	0	0	0	113.8	K154 I155 Q160	K154-N158 WeakPolarHBondContact O-CA 3.49Å; K154-N158 WeakPolarHBondContact O-CB 3.36Å; K154-N158 PolarHBondContact O-N 2.8Å; I155-N158 CarbonylContact O-C 3.42Å; I155-N158 PolarHBondContact O-N 2.98Å; N158-Q160 PolarHBondContact O-N 2.64Å
159	G	48.5	Very low	64.6	Low	39 Å²	39	92.6 Å²	92.6	40%	0.402	47%	0.468	S	S	.	.			trans	-65.4	89	161.1	0	0	0	0	0	107.3	I155 M161	I155-G159 PolarHBondContact O-N 2.92Å; G159-M161 PolarHBondContact O-N 3.2Å
160	Q	61.1	Low	66.9	Low	147 Å²	147	94.1 Å²	94.1	69%	0.687	47%	0.471	S	S	*	.			trans	-66.1	50.8	-177.2	-65.3	-172.6	-39.8	0	0	112.3	N158 H185	N158-Q160 PolarHBondContact O-N 2.64Å; Q160-H185 PolarHBondContact O-CE1 3.22Å; Q160-H185 VanDerWaalsContact O-CE1 3.24Å; Q160-H185 PolarHBondContact O-NE2 3.2Å
161	M	72.3	Confident	69	Low	15 Å²	15	94.3 Å²	94.3	7%	0.074	47%	0.466	C	S	.	.			trans	-121.7	87.3	173.8	-68.2	-64.1	173.9	0	0	106.6	G159 I166 H185 L192 Y228 F231 C240	G159-M161 PolarHBondContact O-N 3.2Å; M161-I166 HydrophobicContact SD-CD1 3.9Å; M161-H185 HydrophobicContact CE-CB 4.39Å; M161-H185 HydrophobicContact SD-CB 4.38Å; M161-H185 PolarHBondContact SD-CD2 2.86Å; M161-L192 HydrophobicContact CE-CD1 3.77Å; M161-L192 HydrophobicContact SD-CD1 3.82Å; M161-Y228 HydrophobicContact CE-CG 4.4Å; M161-F231 HydrophobicContact CB-CD1 4.19Å; M161-F231 WeakPolarHBondContact O-CB 3.5Å; M161-F231 WeakPolarHBondContact O-CD1 3.33Å; M161-C240 HydrophobicContact CG-CB 4.34Å
162	N	80.2	Confident	70.8	Confident	92 Å²	92	92.3 Å²	92.3	49%	0.492	46%	0.458	S	S	.	.			trans	-93.3	147.9	168.3	-54.1	-58.4	0	0	0	108.6	Q164 D165 I166	N162-Q164 PolarHBondContact O-N 3.15Å; N162-Q164 VanDerWaalsContact O-N 3.14Å; N162-D165 WeakPolarHBondContact CB-OD2 3.32Å; N162-D165 PolarHBondContact ND2-OD2 3.46Å; N162-D165 WeakPolarHBondContact O-CB 3.46Å; N162-D165 PolarHBondContact O-N 2.87Å; N162-I166 WeakPolarHBondContact O-CG1 3.36Å
163	E	84.5	Confident	72.7	Confident	87 Å²	87	91.2 Å²	91.2	41%	0.407	46%	0.459	S	S	.	.	G	3₁₀ helix	trans	-50.7	-40.9	174.3	-175.7	-174.7	-154.2	0	0	112.2	D165 I166 F231 V233	E163-D165 PolarHBondContact O-N 2.82Å; E163-D165 VanDerWaalsContact O-N 3.16Å; E163-I166 WeakPolarHBondContact O-CB 3.4Å; E163-I166 PolarHBondContact O-N 2.84Å; E163-F231 HydrophobicContact CB-CD2 4.09Å; E163-F231 HydrophobicContact CB-CE2 3.6Å; E163-F231 HydrophobicContact CB-CZ 4.23Å; E163-F231 HydrophobicContact CG-CE2 4.05Å; E163-V233 HydrophobicContact CB-CG2 3.86Å; E163-V233 VanDerWaalsContact CD-CG2 3.48Å; E163-V233 HydrophobicContact CG-CG2 4.01Å; E163-V233 WeakPolarHBondContact OE2-CG1 3.36Å; E163-V233 WeakPolarHBondContact OE2-CG2 3.1Å
164	Q	87.4	Confident	74.3	Confident	184 Å²	184	91 Å²	91	86%	0.86	46%	0.46	S	S	*	.	G	3₁₀ helix	trans	-62	-24.3	-178.9	-60.5	179.1	8.4	0	0	113.4	N162 I166	N162-Q164 PolarHBondContact O-N 3.15Å; N162-Q164 VanDerWaalsContact O-N 3.14Å; Q164-I166 VanDerWaalsContact C-N 3.35Å
165	D	89.6	Confident	75.1	Confident	43 Å²	43	86.8 Å²	86.8	23%	0.23	46%	0.456	C	S	.	.	G	3₁₀ helix	trans	-87.8	-7.6	179.9	-65.3	-44.5	0	0	0	112.3	N162 E163 H185 V186 P187	N162-D165 WeakPolarHBondContact CB-OD2 3.32Å; N162-D165 PolarHBondContact ND2-OD2 3.46Å; N162-D165 WeakPolarHBondContact O-CB 3.46Å; N162-D165 PolarHBondContact O-N 2.87Å; E163-D165 PolarHBondContact O-N 2.82Å; E163-D165 VanDerWaalsContact O-N 3.16Å; D165-H185 WeakPolarHBondContact O-CA 3.26Å; D165-V186 PolarHBondContact O-N 3.29Å; D165-P187 HydrophobicContact CB-CG 3.79Å; D165-P187 WeakPolarHBondContact OD1-CG 3.46Å
166	I	92.8	Very high	75.5	Confident	11 Å²	11	88.3 Å²	88.3	6%	0.056	47%	0.465	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.2	118.6	-174.6	-57.8	-68.3	0	0	0	110.2	M161 N162 E163 Q164 Y168 A183 H185 L192 V194 F231	M161-I166 HydrophobicContact SD-CD1 3.9Å; N162-I166 WeakPolarHBondContact O-CG1 3.36Å; E163-I166 WeakPolarHBondContact O-CB 3.4Å; E163-I166 PolarHBondContact O-N 2.84Å; Q164-I166 VanDerWaalsContact C-N 3.35Å; I166-Y168 HydrophobicContact CB-CE2 4.37Å; I166-Y168 HydrophobicContact CG2-CD1 4.49Å; I166-Y168 HydrophobicContact CG2-CD2 4.13Å; I166-Y168 HydrophobicContact CG2-CE1 4.23Å; I166-Y168 HydrophobicContact CG2-CE2 3.82Å; I166-Y168 HydrophobicContact CG2-CG 4.46Å; I166-A183 HydrophobicContact CG2-CB 3.6Å; I166-H185 HydrophobicContact CD1-CB 4.18Å; I166-L192 HydrophobicContact CD1-CD1 3.82Å; I166-V194 HydrophobicContact CG2-CG2 4.22Å; I166-F231 HydrophobicContact CG1-CE1 4.04Å; I166-F231 HydrophobicContact CG1-CZ 4.24Å
167	R	94.9	Very high	76.4	Confident	163 Å²	163	84.1 Å²	84.1	62%	0.615	45%	0.445	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-101.3	102	170.1	-66.4	-175.3	-175.6	178.2	4.2	110.1	A183 Y184 V186	R167-A183 CarbonylContact O-C 3.54Å; R167-A183 VanDerWaalsContact O-CA 3.29Å; R167-A183 WeakPolarHBondContact O-CA 3.45Å; R167-Y184 PolarHBondContact N-O 2.9Å; R167-Y184 PolarHBondContact O-N 3.17Å; R167-V186 HydrophobicContact CG-CG2 3.74Å
168	Y	94	Very high	78	Confident	84 Å²	84	81.3 Å²	81.3	33%	0.329	42%	0.423	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-62.9	143.5	174.8	-63.8	-89.1	0	0	0	111.4	I166 Y181 V194 V196	I166-Y168 HydrophobicContact CB-CE2 4.37Å; I166-Y168 HydrophobicContact CG2-CD1 4.49Å; I166-Y168 HydrophobicContact CG2-CD2 4.13Å; I166-Y168 HydrophobicContact CG2-CE1 4.23Å; I166-Y168 HydrophobicContact CG2-CE2 3.82Å; I166-Y168 HydrophobicContact CG2-CG 4.46Å; Y168-Y181 HydrophobicContact CD1-CD1 4.39Å; Y168-Y181 HydrophobicContact CD1-CD2 4.09Å; Y168-Y181 AromaticContact CD1-CG 3.81Å; Y168-Y181 HydrophobicContact CD1-CG 3.81Å; Y168-Y181 HydrophobicContact CE1-CD2 4.17Å; Y168-Y181 HydrophobicContact CE1-CG 4.33Å; Y168-V194 HydrophobicContact CE1-CB 4.13Å; Y168-V194 HydrophobicContact CE1-CG1 3.87Å; Y168-V196 HydrophobicContact CE1-CG2 4.21Å
169	R	93	Very high	80.2	Confident	144 Å²	144	77.6 Å²	77.6	54%	0.543	41%	0.405	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-127.4	-118.7	176.7	-61.5	-170.3	-179.5	-170.5	2.3	109.5	K182	R169-K182 WeakPolarHBondContact CA-O 3.28Å; R169-K182 WeakPolarHBondContact CB-O 3.47Å; R169-K182 PolarHBondContact N-O 2.83Å
170	D	91.4	Very high	82.2	Confident	97 Å²	97	77.6 Å²	77.6	52%	0.519	40%	0.397	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-76	142.3	-174.1	-43.6	-61	0	0	0	111.3	L172 K182	D170-L172 PolarHBondContact O-N 3.37Å; D170-K182 HydrophobicContact CB-CB 4.47Å; D170-K182 PolarHBondContact O-N 3.15Å
171	T	93.1	Very high	83.8	Confident	69 Å²	69	73.9 Å²	73.9	42%	0.423	38%	0.377	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-73.7	122.5	166.5	-55	0	0	0	0	109.3	H174 T179	T171-H174 VanDerWaalsContact CG2-CE1 3.49Å; T171-H174 WeakPolarHBondContact CG2-CE1 3.38Å; T171-T179 HydrophobicContact CG2-CG2 3.56Å
172	L	87.8	Confident	84.9	Confident	80 Å²	80	75.2 Å²	75.2	42%	0.419	38%	0.382	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.7	-31.8	179.8	-64	175.1	0	0	0	112.1	D170 V180 K182 A193 F243	D170-L172 PolarHBondContact O-N 3.37Å; L172-V180 HydrophobicContact CB-CB 4.38Å; L172-V180 HydrophobicContact CB-CG1 4.24Å; L172-V180 HydrophobicContact CD1-CG1 4.18Å; L172-V180 PolarHBondContact N-O 3.26Å; L172-K182 HydrophobicContact CD1-CB 4.01Å; L172-K182 HydrophobicContact CD2-CB 3.99Å; L172-K182 HydrophobicContact CG-CB 3.96Å; L172-A193 HydrophobicContact CD1-CB 4.28Å; L172-F243 HydrophobicContact CD1-CD2 3.86Å; L172-F243 HydrophobicContact CD1-CE2 3.6Å; L172-F243 HydrophobicContact CD2-CE2 3.8Å; L172-F243 HydrophobicContact CD2-CZ 4.42Å; L172-F243 HydrophobicContact CG-CE2 4.36Å
173	G	83	Confident	85.7	Confident	28 Å²	28	70.9 Å²	70.9	29%	0.289	36%	0.359	S	S	.	.	E	Extended strand (participates in β ladder)	trans	179.8	164.7	179.3	0	0	0	0	0	113.5	V180	G173-V180 PolarHBondContact N-O 2.9Å; G173-V180 PolarHBondContact O-N 2.93Å
174	H	79.3	Confident	86.2	Confident	148 Å²	148	70.2 Å²	70.2	69%	0.685	35%	0.354	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-121.6	130.3	172.9	-56.3	83.4	0	0	0	107.7	T171 T179	T171-H174 VanDerWaalsContact CG2-CE1 3.49Å; T171-H174 WeakPolarHBondContact CG2-CE1 3.38Å; H174-T179 PolarHBondContact CD2-OG1 2.89Å
175	G	64.6	Low	86.5	Confident	51 Å²	51	61.6 Å²	61.6	53%	0.526	31%	0.313	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-132.3	174.8	175.1	0	0	0	0	0	111.7	G177 G178	G175-G177 PolarHBondContact O-N 2.91Å; G175-G178 PolarHBondContact N-O 3.31Å; G175-G178 PolarHBondContact O-N 3.12Å
176	N	54.8	Low	86.7	Confident	93 Å²	93	62.3 Å²	62.3	50%	0.497	32%	0.319	S	S	.	.	T	Hydrogen-bonded Turn	trans	-56.3	-22.2	179	-70.8	3.9	0	0	0	113.3
177	G	65	Low	86.6	Confident	7 Å²	7	65.4 Å²	65.4	7%	0.072	34%	0.34	C	S	.	.	T	Hydrogen-bonded Turn	trans	-100.6	15.4	178.3	0	0	0	0	0	115.3	G175 I197	G175-G177 PolarHBondContact O-N 2.91Å; G177-I197 WeakPolarHBondContact O-CB 3.09Å; G177-I197 WeakPolarHBondContact O-CD1 3.45Å; G177-I197 WeakPolarHBondContact O-CG1 3.28Å; G177-I197 VanDerWaalsContact O-CG2 3.28Å; G177-I197 WeakPolarHBondContact O-CG2 3.47Å
178	G	78.6	Confident	86.3	Confident	20 Å²	20	60.3 Å²	60.3	21%	0.206	33%	0.329	C	S	.	.	E	Extended strand (participates in β ladder)	trans	117.3	-163.1	176.9	0	0	0	0	0	114.8	G175 V196	G175-G178 PolarHBondContact N-O 3.31Å; G175-G178 PolarHBondContact O-N 3.12Å; G178-V196 WeakPolarHBondContact CA-O 3.35Å
179	T	87.8	Confident	86.2	Confident	28 Å²	28	58 Å²	58	17%	0.172	33%	0.332	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-110	135.2	-172.4	-52.9	0	0	0	0	110.8	T171 H174 Y181 V196	T171-T179 HydrophobicContact CG2-CG2 3.56Å; H174-T179 PolarHBondContact CD2-OG1 2.89Å; T179-Y181 HydrophobicContact CG2-CD2 4.2Å; T179-Y181 HydrophobicContact CG2-CE1 4.02Å; T179-Y181 HydrophobicContact CG2-CE2 3.56Å; T179-Y181 VanDerWaalsContact CG2-CZ 3.45Å; T179-V196 PolarHBondContact N-O 3.45Å; T179-V196 PolarHBondContact O-N 2.8Å
180	V	91.6	Very high	86.1	Confident	39 Å²	39	56 Å²	56	24%	0.236	33%	0.327	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-104	125.7	177.2	-171.2	0	0	0	0	109.4	L172 G173 A193 V194 K195	L172-V180 HydrophobicContact CB-CB 4.38Å; L172-V180 HydrophobicContact CB-CG1 4.24Å; L172-V180 HydrophobicContact CD1-CG1 4.18Å; L172-V180 PolarHBondContact N-O 3.26Å; G173-V180 PolarHBondContact N-O 2.9Å; G173-V180 PolarHBondContact O-N 2.93Å; V180-A193 HydrophobicContact CG1-CB 4.3Å; V180-V194 WeakPolarHBondContact CA-O 3.29Å; V180-K195 HydrophobicContact CG2-CB 4.14Å; V180-K195 HydrophobicContact CG2-CD 4.33Å; V180-K195 HydrophobicContact CG2-CG 4.02Å
181	Y	94.4	Very high	86.3	Confident	68 Å²	68	54.9 Å²	54.9	27%	0.267	32%	0.32	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.7	143.9	178.4	-61.6	-88.2	0	0	0	111	Y168 T179 A193 V194 V196	Y168-Y181 HydrophobicContact CD1-CD1 4.39Å; Y168-Y181 HydrophobicContact CD1-CD2 4.09Å; Y168-Y181 AromaticContact CD1-CG 3.81Å; Y168-Y181 HydrophobicContact CD1-CG 3.81Å; Y168-Y181 HydrophobicContact CE1-CD2 4.17Å; Y168-Y181 HydrophobicContact CE1-CG 4.33Å; T179-Y181 HydrophobicContact CG2-CD2 4.2Å; T179-Y181 HydrophobicContact CG2-CE1 4.02Å; T179-Y181 HydrophobicContact CG2-CE2 3.56Å; T179-Y181 VanDerWaalsContact CG2-CZ 3.45Å; Y181-A193 CarbonylContact O-C 3.54Å; Y181-A193 WeakPolarHBondContact O-CA 3.42Å; Y181-V194 PolarHBondContact N-O 3.25Å; Y181-V194 PolarHBondContact O-N 2.94Å; Y181-V196 HydrophobicContact CD2-CG2 3.82Å; Y181-V196 HydrophobicContact CE2-CB 4.19Å; Y181-V196 HydrophobicContact CE2-CG2 3.86Å
182	K	96.1	Very high	86.3	Confident	43 Å²	43	51.6 Å²	51.6	19%	0.187	30%	0.3	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-74.5	131.2	158.6	-170.5	176.5	-177.4	178.1	0	107.4	R169 D170 L172 I191 L192 F243	R169-K182 WeakPolarHBondContact CA-O 3.28Å; R169-K182 WeakPolarHBondContact CB-O 3.47Å; R169-K182 PolarHBondContact N-O 2.83Å; D170-K182 HydrophobicContact CB-CB 4.47Å; D170-K182 PolarHBondContact O-N 3.15Å; L172-K182 HydrophobicContact CD1-CB 4.01Å; L172-K182 HydrophobicContact CD2-CB 3.99Å; L172-K182 HydrophobicContact CG-CB 3.96Å; K182-I191 HydrophobicContact CD-CG2 4.49Å; K182-I191 HydrophobicContact CG-CG2 3.99Å; K182-L192 WeakPolarHBondContact CA-O 3.45Å; K182-F243 HydrophobicContact CD-CE1 4.34Å; K182-F243 HydrophobicContact CD-CE2 4.21Å; K182-F243 HydrophobicContact CD-CZ 3.97Å; K182-F243 HydrophobicContact CG-CD2 4.35Å; K182-F243 HydrophobicContact CG-CE2 4.19Å; K182-F243 HydrophobicContact CG-CZ 4.4Å
183	A	96	Very high	86.7	Confident	1 Å²	1	48.4 Å²	48.4	1%	0.008	29%	0.285	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-136.9	162.9	177.9	0	0	0	0	0	111.7	I166 R167 I191 L192 V194	I166-A183 HydrophobicContact CG2-CB 3.6Å; R167-A183 CarbonylContact O-C 3.54Å; R167-A183 VanDerWaalsContact O-CA 3.29Å; R167-A183 WeakPolarHBondContact O-CA 3.45Å; A183-I191 CarbonylContact O-C 3.57Å; A183-I191 WeakPolarHBondContact O-CA 3.26Å; A183-L192 PolarHBondContact N-O 3.45Å; A183-L192 PolarHBondContact O-N 2.98Å; A183-V194 HydrophobicContact CB-CG2 3.63Å
184	Y	95.5	Very high	87.2	Confident	73 Å²	73	47 Å²	47	29%	0.286	27%	0.271	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.7	121.7	173.5	-179.7	-101	0	0	0	109.1	R167 V186 G189 I191	R167-Y184 PolarHBondContact N-O 2.9Å; R167-Y184 PolarHBondContact O-N 3.17Å; Y184-V186 HydrophobicContact CD1-CG2 4.11Å; Y184-V186 HydrophobicContact CE1-CG2 4.35Å; Y184-V186 PolarHBondContact O-N 3.45Å; Y184-G189 WeakPolarHBondContact CE2-O 3.34Å; Y184-G189 WeakPolarHBondContact OH-CA 3.49Å; Y184-I191 HydrophobicContact CD2-CG1 4.38Å
185	H	94	Very high	87.7	Confident	3 Å²	3	41.4 Å²	41.4	1%	0.014	25%	0.245	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-86.1	111.2	174.3	-176.6	-119	0	0	0	109.6	Q160 M161 D165 I166 P187 S188 G189 K190 L192	Q160-H185 PolarHBondContact O-CE1 3.22Å; Q160-H185 VanDerWaalsContact O-CE1 3.24Å; Q160-H185 PolarHBondContact O-NE2 3.2Å; M161-H185 HydrophobicContact CE-CB 4.39Å; M161-H185 HydrophobicContact SD-CB 4.38Å; M161-H185 PolarHBondContact SD-CD2 2.86Å; D165-H185 WeakPolarHBondContact O-CA 3.26Å; I166-H185 HydrophobicContact CD1-CB 4.18Å; H185-P187 WeakPolarHBondContact NE2-CD 3.08Å; H185-S188 WeakPolarHBondContact ND1-CB 3.42Å; H185-S188 PolarHBondContact ND1-N 3.15Å; H185-S188 PolarHBondContact ND1-OG 3.21Å; H185-G189 WeakPolarHBondContact O-CA 3.34Å; H185-G189 PolarHBondContact O-N 2.93Å; H185-K190 PolarHBondContact N-O 3.39Å; H185-L192 HydrophobicContact CB-CD1 3.78Å; H185-L192 HydrophobicContact CB-CG 4.1Å
186	V	92.9	Very high	88.8	Confident	59 Å²	59	39.7 Å²	39.7	36%	0.358	22%	0.224	S	C	.	.	T	Hydrogen-bonded Turn	trans	-62.1	-47.9	-170.4	178.9	0	0	0	0	112.6	D165 R167 Y184 S188	D165-V186 PolarHBondContact O-N 3.29Å; R167-V186 HydrophobicContact CG-CG2 3.74Å; Y184-V186 HydrophobicContact CD1-CG2 4.11Å; Y184-V186 HydrophobicContact CE1-CG2 4.35Å; Y184-V186 PolarHBondContact O-N 3.45Å; V186-S188 PolarHBondContact O-N 3.37Å
187	P	90.9	Very high	90.2	Very high	76 Å²	76	35.5 Å²	35.5	49%	0.494	20%	0.201	S	C	.	.	T	Hydrogen-bonded Turn	trans	-63.5	-40	-178	-23.6	33.5	0	0	0	114.3	D165 H185	D165-P187 HydrophobicContact CB-CG 3.79Å; D165-P187 WeakPolarHBondContact OD1-CG 3.46Å; H185-P187 WeakPolarHBondContact NE2-CD 3.08Å
188	S	89.2	Confident	90.8	Very high	55 Å²	55	41.1 Å²	41.1	39%	0.385	23%	0.229	S	C	.	.	T	Hydrogen-bonded Turn	trans	-94.7	-10.5	-176.3	74.1	0	0	0	0	114.2	H185 V186 K190	H185-S188 WeakPolarHBondContact ND1-CB 3.42Å; H185-S188 PolarHBondContact ND1-N 3.15Å; H185-S188 PolarHBondContact ND1-OG 3.21Å; V186-S188 PolarHBondContact O-N 3.37Å; S188-K190 PolarHBondContact O-N 3.35Å; S188-K190 WeakPolarHBondContact OG-CB 3.37Å; S188-K190 WeakPolarHBondContact OG-CG 3.36Å; S188-K190 PolarHBondContact OG-N 2.65Å
189	G	90.3	Very high	90.4	Very high	37 Å²	37	40.5 Å²	40.5	38%	0.381	22%	0.221	S	C	.	.	T	Hydrogen-bonded Turn	trans	67.1	15.7	-175.4	0	0	0	0	0	114.9	Y184 H185	Y184-G189 WeakPolarHBondContact CE2-O 3.34Å; Y184-G189 WeakPolarHBondContact OH-CA 3.49Å; H185-G189 WeakPolarHBondContact O-CA 3.34Å; H185-G189 PolarHBondContact O-N 2.93Å
190	K	91	Very high	89.6	Confident	100 Å²	100	45.9 Å²	45.9	44%	0.435	25%	0.249	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-91.2	144.1	-176.1	-65.8	-176.1	-178.5	179.7	0	112	H185 S188 L192	H185-K190 PolarHBondContact N-O 3.39Å; S188-K190 PolarHBondContact O-N 3.35Å; S188-K190 WeakPolarHBondContact OG-CB 3.37Å; S188-K190 WeakPolarHBondContact OG-CG 3.36Å; S188-K190 PolarHBondContact OG-N 2.65Å; K190-L192 HydrophobicContact CB-CD2 3.95Å
191	I	95.4	Very high	88.3	Confident	75 Å²	75	45.5 Å²	45.5	39%	0.385	25%	0.245	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-85.4	131.7	166.3	-58.4	175.3	0	0	0	108.4	K182 A183 Y184 F243	K182-I191 HydrophobicContact CD-CG2 4.49Å; K182-I191 HydrophobicContact CG-CG2 3.99Å; A183-I191 CarbonylContact O-C 3.57Å; A183-I191 WeakPolarHBondContact O-CA 3.26Å; Y184-I191 HydrophobicContact CD2-CG1 4.38Å; I191-F243 HydrophobicContact CB-CB 4.47Å; I191-F243 HydrophobicContact CG2-CB 3.85Å; I191-F243 HydrophobicContact CG2-CD1 3.65Å; I191-F243 HydrophobicContact CG2-CE1 4.39Å; I191-F243 HydrophobicContact CG2-CG 3.79Å
192	L	95.1	Very high	87.2	Confident	0 Å²	0	45.9 Å²	45.9	0%	0	25%	0.254	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122	158.2	-174.7	-52.4	-167.4	0	0	0	111.7	M161 I166 K182 A183 H185 K190 V194 Y228 C240 T241	M161-L192 HydrophobicContact CE-CD1 3.77Å; M161-L192 HydrophobicContact SD-CD1 3.82Å; I166-L192 HydrophobicContact CD1-CD1 3.82Å; K182-L192 WeakPolarHBondContact CA-O 3.45Å; A183-L192 PolarHBondContact N-O 3.45Å; A183-L192 PolarHBondContact O-N 2.98Å; H185-L192 HydrophobicContact CB-CD1 3.78Å; H185-L192 HydrophobicContact CB-CG 4.1Å; K190-L192 HydrophobicContact CB-CD2 3.95Å; L192-V194 HydrophobicContact CB-CG2 4.19Å; L192-Y228 HydrophobicContact CD2-CD2 3.31Å; L192-Y228 HydrophobicContact CD2-CE2 3.34Å; L192-Y228 HydrophobicContact CG-CD2 4.49Å; L192-C240 HydrophobicContact CD1-CB 4.2Å; L192-T241 WeakPolarHBondContact CA-O 3.43Å
193	A	95	Very high	85.9	Confident	12 Å²	12	49.2 Å²	49.2	10%	0.099	27%	0.274	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-101.2	128.1	155.4	0	0	0	0	0	108.4	L172 V180 Y181 T241	L172-A193 HydrophobicContact CD1-CB 4.28Å; V180-A193 HydrophobicContact CG1-CB 4.3Å; Y181-A193 CarbonylContact O-C 3.54Å; Y181-A193 WeakPolarHBondContact O-CA 3.42Å; A193-T241 PolarHBondContact N-O 3.17Å; A193-T241 PolarHBondContact O-N 3Å; A193-T241 PolarHBondContact O-OG1 2.88Å
194	V	93.2	Very high	84.7	Confident	0 Å²	0	55.4 Å²	55.4	0%	0	30%	0.303	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-120	108.7	-178.6	-175.2	0	0	0	0	108.9	I166 Y168 V180 Y181 A183 L192 V196 I239	I166-V194 HydrophobicContact CG2-CG2 4.22Å; Y168-V194 HydrophobicContact CE1-CB 4.13Å; Y168-V194 HydrophobicContact CE1-CG1 3.87Å; V180-V194 WeakPolarHBondContact CA-O 3.29Å; Y181-V194 PolarHBondContact N-O 3.25Å; Y181-V194 PolarHBondContact O-N 2.94Å; A183-V194 HydrophobicContact CB-CG2 3.63Å; L192-V194 HydrophobicContact CB-CG2 4.19Å; V194-V196 HydrophobicContact CG1-CG2 4.14Å; V194-I239 CarbonylContact C-O 3.4Å; V194-I239 WeakPolarHBondContact CA-O 3.42Å
195	K	90	Very high	83.5	Confident	30 Å²	30	53.9 Å²	53.9	13%	0.13	30%	0.299	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.4	115.2	175.9	-176.6	171	-177.8	175.3	0	109.4	V180 I197 S238 I239 D301	V180-K195 HydrophobicContact CG2-CB 4.14Å; V180-K195 HydrophobicContact CG2-CD 4.33Å; V180-K195 HydrophobicContact CG2-CG 4.02Å; K195-I197 HydrophobicContact CG-CD1 4.48Å; K195-I197 HydrophobicContact CG-CG1 4.21Å; K195-S238 CarbonylContact O-C 3.5Å; K195-S238 WeakPolarHBondContact O-CA 3.44Å; K195-I239 HydrophobicContact CB-CB 4.42Å; K195-I239 PolarHBondContact N-O 3.44Å; K195-I239 PolarHBondContact O-N 3.41Å; K195-D301 IonicContact NZ-OD1 3.69Å; K195-D301 PolarHBondContact NZ-OD1 3.27Å; K195-D301 IonicContact NZ-OD2 3.59Å; K195-D301 PolarHBondContact NZ-OD2 3.46Å
196	V	88.2	Confident	82.4	Confident	14 Å²	14	56.5 Å²	56.5	9%	0.085	31%	0.311	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.4	119.2	-179.3	-175.5	0	0	0	0	109.1	Y168 G178 T179 Y181 V194 R236 I237	Y168-V196 HydrophobicContact CE1-CG2 4.21Å; G178-V196 WeakPolarHBondContact CA-O 3.35Å; T179-V196 PolarHBondContact N-O 3.45Å; T179-V196 PolarHBondContact O-N 2.8Å; Y181-V196 HydrophobicContact CD2-CG2 3.82Å; Y181-V196 HydrophobicContact CE2-CB 4.19Å; Y181-V196 HydrophobicContact CE2-CG2 3.86Å; V194-V196 HydrophobicContact CG1-CG2 4.14Å; V196-R236 HydrophobicContact CG1-CB 4.18Å; V196-R236 HydrophobicContact CG1-CG 4.39Å; V196-I237 WeakPolarHBondContact CA-O 3.31Å
197	I	83.2	Confident	81.3	Confident	5 Å²	5	60.7 Å²	60.7	3%	0.026	33%	0.325	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.8	125.4	-178	-40.5	-169	0	0	0	108.1	G177 K195 L199 R236 I237 I239 V309	G177-I197 WeakPolarHBondContact O-CB 3.09Å; G177-I197 WeakPolarHBondContact O-CD1 3.45Å; G177-I197 WeakPolarHBondContact O-CG1 3.28Å; G177-I197 VanDerWaalsContact O-CG2 3.28Å; G177-I197 WeakPolarHBondContact O-CG2 3.47Å; K195-I197 HydrophobicContact CG-CD1 4.48Å; K195-I197 HydrophobicContact CG-CG1 4.21Å; I197-L199 HydrophobicContact CB-CG 4.49Å; I197-L199 HydrophobicContact CG2-CD2 3.75Å; I197-L199 HydrophobicContact CG2-CG 4.08Å; I197-R236 CarbonylContact O-C 3.5Å; I197-R236 VanDerWaalsContact O-CA 3.24Å; I197-R236 WeakPolarHBondContact O-CA 3.06Å; I197-I237 HydrophobicContact CB-CG2 3.69Å; I197-I237 HydrophobicContact CD1-CG2 4.29Å; I197-I237 HydrophobicContact CG1-CG2 4.02Å; I197-I237 PolarHBondContact N-O 3.29Å; I197-I237 PolarHBondContact O-N 3.08Å; I197-I239 HydrophobicContact CD1-CD1 4.2Å; I197-V309 HydrophobicContact CD1-CG2 3.91Å
198	L	77.9	Confident	80.3	Confident	125 Å²	125	62.3 Å²	62.3	65%	0.654	33%	0.326	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-80.1	126.3	172.8	-84.5	72.4	0	0	0	109.1	R236	L198-R236 HydrophobicContact CD1-CG 4.15Å; L198-R236 HydrophobicContact CG-CG 3.99Å
199	L	71.7	Confident	79.6	Confident	7 Å²	7	59.7 Å²	59.7	4%	0.037	31%	0.307	C	S	.	.			trans	-136.2	137	-175.1	-63.4	-173.7	0	0	0	109.5	I197 I201 I209 N235 I237 I312	I197-L199 HydrophobicContact CB-CG 4.49Å; I197-L199 HydrophobicContact CG2-CD2 3.75Å; I197-L199 HydrophobicContact CG2-CG 4.08Å; L199-I201 HydrophobicContact CB-CD1 3.95Å; L199-I201 HydrophobicContact CB-CG1 3.36Å; L199-I201 HydrophobicContact CD1-CG1 4.31Å; L199-I201 HydrophobicContact CG-CG1 4.44Å; L199-I201 WeakPolarHBondContact O-CG1 3.49Å; L199-I201 PolarHBondContact O-N 2.99Å; L199-I201 VanDerWaalsContact O-N 3.15Å; L199-I209 HydrophobicContact CD1-CD1 3.62Å; L199-N235 PolarHBondContact N-O 2.85Å; L199-N235 CarbonylContact O-C 3.55Å; L199-N235 VanDerWaalsContact O-C 3.3Å; L199-N235 WeakPolarHBondContact O-CA 3.4Å; L199-N235 WeakPolarHBondContact O-CB 3.13Å; L199-I237 HydrophobicContact CD1-CB 4.14Å; L199-I237 HydrophobicContact CD1-CG2 3.41Å; L199-I237 VanDerWaalsContact CD1-CG2 3.41Å; L199-I237 HydrophobicContact CG-CG2 4.1Å; L199-I312 HydrophobicContact CD1-CD1 4.14Å; L199-I312 HydrophobicContact CD2-CB 3.84Å; L199-I312 HydrophobicContact CD2-CD1 3.11Å; L199-I312 HydrophobicContact CD2-CG1 3.41Å; L199-I312 VanDerWaalsContact CD2-CG1 3.41Å; L199-I312 HydrophobicContact CD2-CG2 3.29Å; L199-I312 HydrophobicContact CG-CD1 4.27Å
200	D	70.5	Confident	78.7	Confident	141 Å²	141	60.2 Å²	60.2	75%	0.754	30%	0.301	S	S	*	.			trans	-80.8	92.7	163.3	-159.4	7	0	0	0	107.7	T202 N235	D200-T202 PolarHBondContact O-N 2.81Å; D200-N235 PolarHBondContact OD1-ND2 3.32Å
201	I	63.8	Low	77.6	Confident	31 Å²	31	59.1 Å²	59.1	16%	0.159	31%	0.306	C	S	.	.			trans	-88.6	111.9	-164.2	-59.4	170.5	0	0	0	109.8	L199 Q206 F232	L199-I201 HydrophobicContact CB-CD1 3.95Å; L199-I201 HydrophobicContact CB-CG1 3.36Å; L199-I201 HydrophobicContact CD1-CG1 4.31Å; L199-I201 HydrophobicContact CG-CG1 4.44Å; L199-I201 WeakPolarHBondContact O-CG1 3.49Å; L199-I201 PolarHBondContact O-N 2.99Å; L199-I201 VanDerWaalsContact O-N 3.15Å; I201-Q206 HydrophobicContact CG2-CB 3.73Å; I201-Q206 HydrophobicContact CG2-CG 4.18Å; I201-F232 HydrophobicContact CD1-CD1 3.64Å; I201-F232 HydrophobicContact CD1-CE1 4.12Å
202	T	71.3	Confident	76.4	Confident	76 Å²	76	57.4 Å²	57.4	47%	0.466	30%	0.296	S	S	.	.			trans	-82.7	155.4	158.1	67.3	0	0	0	0	110.3	D200 E204 L205 Q206	D200-T202 PolarHBondContact O-N 2.81Å; T202-E204 PolarHBondContact O-N 2.81Å; T202-L205 PolarHBondContact O-N 3.35Å; T202-L205 VanDerWaalsContact OG1-CB 3.31Å; T202-L205 WeakPolarHBondContact OG1-CB 3.49Å; T202-L205 PolarHBondContact OG1-N 3.19Å; T202-L205 VanDerWaalsContact OG1-N 3.15Å; T202-Q206 PolarHBondContact O-N 3.31Å
203	L	68.3	Low	75.5	Confident	114 Å²	114	57.7 Å²	57.7	60%	0.597	30%	0.297	S	S	*	.	H	α-helix	trans	-61	-32.8	177.1	-73.4	171.9	0	0	0	112	K207	L203-K207 WeakPolarHBondContact O-CG 3.33Å; L203-K207 PolarHBondContact O-N 2.98Å; L203-K207 VanDerWaalsContact O-N 3.09Å
204	E	71.1	Confident	74.4	Confident	131 Å²	131	59 Å²	59	61%	0.612	30%	0.301	S	S	*	.	H	α-helix	trans	-65.4	-48.6	175.1	-67.6	67.7	-144.3	0	0	111	T202 Q206 K207 Q208	T202-E204 PolarHBondContact O-N 2.81Å; E204-Q206 VanDerWaalsContact C-N 3.31Å; E204-Q206 PolarHBondContact O-N 3.34Å; E204-K207 PolarHBondContact O-N 2.51Å; E204-Q208 PolarHBondContact O-N 2.97Å
205	L	70.6	Confident	73.4	Confident	40 Å²	40	61.9 Å²	61.9	21%	0.209	32%	0.316	C	S	.	.	H	α-helix	trans	-61.8	-42.2	177	-178.9	61.2	0	0	0	110.5	T202 K207 Q208 I209	T202-L205 PolarHBondContact O-N 3.35Å; T202-L205 VanDerWaalsContact OG1-CB 3.31Å; T202-L205 WeakPolarHBondContact OG1-CB 3.49Å; T202-L205 PolarHBondContact OG1-N 3.19Å; T202-L205 VanDerWaalsContact OG1-N 3.15Å; L205-K207 VanDerWaalsContact C-N 3.35Å; L205-K207 PolarHBondContact O-N 3.28Å; L205-Q208 PolarHBondContact O-N 3.4Å; L205-I209 HydrophobicContact CD1-CD1 4.21Å; L205-I209 HydrophobicContact CD1-CG1 4.28Å; L205-I209 HydrophobicContact CD2-CD1 4.49Å; L205-I209 HydrophobicContact CG-CD1 3.82Å; L205-I209 HydrophobicContact CG-CG1 4.34Å; L205-I209 WeakPolarHBondContact O-CB 3.43Å; L205-I209 WeakPolarHBondContact O-CG1 3.34Å; L205-I209 PolarHBondContact O-N 2.99Å
206	Q	70.2	Confident	72.8	Confident	58 Å²	58	61.2 Å²	61.2	27%	0.271	31%	0.314	S	S	.	.	H	α-helix	trans	-57.3	-46.1	176.2	-163	-174.6	-1	0	0	112.3	I201 T202 E204 I209 M210 F232	I201-Q206 HydrophobicContact CG2-CB 3.73Å; I201-Q206 HydrophobicContact CG2-CG 4.18Å; T202-Q206 PolarHBondContact O-N 3.31Å; E204-Q206 VanDerWaalsContact C-N 3.31Å; E204-Q206 PolarHBondContact O-N 3.34Å; Q206-I209 PolarHBondContact O-N 3.44Å; Q206-M210 VanDerWaalsContact O-CG 3.3Å; Q206-M210 WeakPolarHBondContact O-CG 3.43Å; Q206-M210 PolarHBondContact O-N 2.89Å; Q206-F232 HydrophobicContact CB-CZ 4.43Å; Q206-F232 HydrophobicContact CG-CD1 4.12Å; Q206-F232 HydrophobicContact CG-CD2 3.85Å; Q206-F232 HydrophobicContact CG-CE1 3.75Å; Q206-F232 HydrophobicContact CG-CE2 3.45Å; Q206-F232 VanDerWaalsContact CG-CE2 3.45Å; Q206-F232 HydrophobicContact CG-CG 4.14Å; Q206-F232 HydrophobicContact CG-CZ 3.39Å
207	K	69.9	Low	72.3	Confident	148 Å²	148	66.2 Å²	66.2	64%	0.643	33%	0.332	S	S	*	.	H	α-helix	trans	-64.9	-41.3	177.7	-73.9	172.2	-173.5	168.5	0	111.8	L203 E204 L205 M210 S211	L203-K207 WeakPolarHBondContact O-CG 3.33Å; L203-K207 PolarHBondContact O-N 2.98Å; L203-K207 VanDerWaalsContact O-N 3.09Å; E204-K207 PolarHBondContact O-N 2.51Å; L205-K207 VanDerWaalsContact C-N 3.35Å; L205-K207 PolarHBondContact O-N 3.28Å; K207-M210 PolarHBondContact O-N 3.25Å; K207-S211 PolarHBondContact O-N 3.18Å
208	Q	71.2	Confident	72	Confident	109 Å²	109	72 Å²	72	51%	0.509	36%	0.357	S	S	.	.	H	α-helix	trans	-59.3	-52.9	175.6	-178	179.1	-18.3	0	0	110	E204 L205 M210 S211 E212	E204-Q208 PolarHBondContact O-N 2.97Å; L205-Q208 PolarHBondContact O-N 3.4Å; Q208-M210 VanDerWaalsContact C-N 3.27Å; Q208-M210 PolarHBondContact O-N 3.11Å; Q208-S211 PolarHBondContact O-N 3.33Å; Q208-E212 HydrophobicContact CG-CG 4.44Å; Q208-E212 WeakPolarHBondContact CG-OE1 3.41Å; Q208-E212 PolarHBondContact NE2-OE1 3.4Å; Q208-E212 WeakPolarHBondContact O-CB 3.27Å; Q208-E212 WeakPolarHBondContact O-CG 3.49Å; Q208-E212 PolarHBondContact O-N 3.22Å
209	I	72.8	Confident	72.4	Confident	0 Å²	0	66.8 Å²	66.8	0%	0	33%	0.331	C	S	.	.	H	α-helix	trans	-53.2	-45.1	177.6	-66.5	169.2	0	0	0	111.8	L199 L205 Q206 E212 L213 F232 I237 L308	L199-I209 HydrophobicContact CD1-CD1 3.62Å; L205-I209 HydrophobicContact CD1-CD1 4.21Å; L205-I209 HydrophobicContact CD1-CG1 4.28Å; L205-I209 HydrophobicContact CD2-CD1 4.49Å; L205-I209 HydrophobicContact CG-CD1 3.82Å; L205-I209 HydrophobicContact CG-CG1 4.34Å; L205-I209 WeakPolarHBondContact O-CB 3.43Å; L205-I209 WeakPolarHBondContact O-CG1 3.34Å; L205-I209 PolarHBondContact O-N 2.99Å; Q206-I209 PolarHBondContact O-N 3.44Å; I209-E212 CarbonylContact O-C 3.56Å; I209-E212 WeakPolarHBondContact O-CA 3.24Å; I209-E212 VanDerWaalsContact O-CB 3.27Å; I209-E212 WeakPolarHBondContact O-CB 3.26Å; I209-E212 PolarHBondContact O-N 2.98Å; I209-L213 HydrophobicContact CG2-CD1 3.8Å; I209-L213 HydrophobicContact CG2-CG 4.16Å; I209-L213 WeakPolarHBondContact O-CG 3.49Å; I209-L213 PolarHBondContact O-N 2.78Å; I209-F232 HydrophobicContact CB-CZ 4.29Å; I209-F232 HydrophobicContact CD1-CE1 4.37Å; I209-F232 HydrophobicContact CG2-CZ 4.06Å; I209-I237 HydrophobicContact CG2-CD1 3.38Å; I209-L308 HydrophobicContact CB-CD1 4.47Å; I209-L308 HydrophobicContact CD1-CD1 3.68Å; I209-L308 HydrophobicContact CD1-CD2 4.37Å; I209-L308 HydrophobicContact CG1-CD1 3.34Å; I209-L308 HydrophobicContact CG1-CD2 4.11Å; I209-L308 HydrophobicContact CG1-CG 4.36Å; I209-L308 HydrophobicContact CG2-CD2 3.74Å
210	M	72.6	Confident	73.2	Confident	49 Å²	49	73.3 Å²	73.3	24%	0.241	37%	0.366	C	S	.	.	H	α-helix	trans	-68.1	-41.8	-178.5	-73.2	-62	-82.6	0	0	112.8	L156 Q206 K207 Q208 E212 L213 E214 F232	L156-M210 HydrophobicContact CD2-CE 3.62Å; Q206-M210 VanDerWaalsContact O-CG 3.3Å; Q206-M210 WeakPolarHBondContact O-CG 3.43Å; Q206-M210 PolarHBondContact O-N 2.89Å; K207-M210 PolarHBondContact O-N 3.25Å; Q208-M210 VanDerWaalsContact C-N 3.27Å; Q208-M210 PolarHBondContact O-N 3.11Å; M210-E212 PolarHBondContact O-N 3.08Å; M210-L213 PolarHBondContact O-N 3.14Å; M210-E214 PolarHBondContact O-N 2.72Å; M210-F232 HydrophobicContact CG-CE2 3.57Å; M210-F232 HydrophobicContact CG-CZ 3.98Å; M210-F232 HydrophobicContact SD-CE2 3.52Å; M210-F232 VanDerWaalsContact SD-CE2 3.52Å; M210-F232 HydrophobicContact SD-CZ 4.11Å
211	S	67.3	Low	74.4	Confident	77 Å²	77	67.7 Å²	67.7	54%	0.538	34%	0.338	S	S	.	.	H	α-helix	trans	-61.5	-31.1	172.4	-174.7	0	0	0	0	111.7	K207 Q208 E214	K207-S211 PolarHBondContact O-N 3.18Å; Q208-S211 PolarHBondContact O-N 3.33Å; S211-E214 WeakPolarHBondContact O-CB 3.31Å
212	E	70.4	Confident	75.9	Confident	38 Å²	38	70 Å²	70	18%	0.178	36%	0.357	C	S	.	.	H	α-helix	trans	-76.5	-42.9	-177.9	-95.1	-169	-154.3	0	0	112.3	Q208 I209 M210 E214 I215 V304	Q208-E212 HydrophobicContact CG-CG 4.44Å; Q208-E212 WeakPolarHBondContact CG-OE1 3.41Å; Q208-E212 PolarHBondContact NE2-OE1 3.4Å; Q208-E212 WeakPolarHBondContact O-CB 3.27Å; Q208-E212 WeakPolarHBondContact O-CG 3.49Å; Q208-E212 PolarHBondContact O-N 3.22Å; I209-E212 CarbonylContact O-C 3.56Å; I209-E212 WeakPolarHBondContact O-CA 3.24Å; I209-E212 VanDerWaalsContact O-CB 3.27Å; I209-E212 WeakPolarHBondContact O-CB 3.26Å; I209-E212 PolarHBondContact O-N 2.98Å; M210-E212 PolarHBondContact O-N 3.08Å; E212-E214 PolarHBondContact O-N 2.83Å; E212-I215 PolarHBondContact O-N 2.95Å; E212-V304 HydrophobicContact CB-CB 4.46Å; E212-V304 HydrophobicContact CB-CG1 3.08Å; E212-V304 VanDerWaalsContact CD-CG1 3.45Å; E212-V304 HydrophobicContact CG-CG1 3.22Å; E212-V304 WeakPolarHBondContact OE2-CG1 3.13Å
213	L	76.3	Confident	77.1	Confident	7 Å²	7	69.8 Å²	69.8	4%	0.037	35%	0.348	C	S	.	.	H	α-helix	trans	-69.8	-19.1	174.1	-68.2	175	0	0	0	113.3	I209 M210 I215 L216 Y217 F227 A230 I237 I239	I209-L213 HydrophobicContact CG2-CD1 3.8Å; I209-L213 HydrophobicContact CG2-CG 4.16Å; I209-L213 WeakPolarHBondContact O-CG 3.49Å; I209-L213 PolarHBondContact O-N 2.78Å; M210-L213 PolarHBondContact O-N 3.14Å; L213-I215 PolarHBondContact O-N 3.02Å; L213-L216 HydrophobicContact CD2-CD1 3.54Å; L213-L216 HydrophobicContact CD2-CG 4.46Å; L213-L216 WeakPolarHBondContact O-CB 3.41Å; L213-L216 PolarHBondContact O-N 3.29Å; L213-Y217 PolarHBondContact O-N 2.94Å; L213-F227 HydrophobicContact CB-CZ 4.39Å; L213-A230 HydrophobicContact CD1-CB 3.59Å; L213-I237 HydrophobicContact CD1-CD1 3.65Å; L213-I239 HydrophobicContact CD1-CG1 4.45Å; L213-I239 HydrophobicContact CD2-CD1 4.04Å; L213-I239 HydrophobicContact CD2-CG1 4.45Å
214	E	72	Confident	78.4	Confident	39 Å²	39	64.5 Å²	64.5	18%	0.182	32%	0.32	C	S	.	.	H	α-helix	trans	-56.5	-31.5	173.8	-162.4	-167.3	149.7	0	0	112.1	L152 M210 S211 E212 Y217 K218	L152-E214 WeakPolarHBondContact CD1-OE1 3.27Å; L152-E214 VanDerWaalsContact CD2-CD 3.47Å; L152-E214 WeakPolarHBondContact CD2-OE1 3.33Å; L152-E214 WeakPolarHBondContact CD2-OE2 3Å; M210-E214 PolarHBondContact O-N 2.72Å; S211-E214 WeakPolarHBondContact O-CB 3.31Å; E212-E214 PolarHBondContact O-N 2.83Å; E214-Y217 PolarHBondContact O-N 3.37Å; E214-K218 WeakPolarHBondContact O-CG 3.45Å; E214-K218 PolarHBondContact O-N 3.29Å; E214-K218 WeakPolarHBondContact OE1-CE 3.37Å; E214-K218 IonicContact OE1-NZ 2.61Å; E214-K218 PolarHBondContact OE1-NZ 3.04Å
215	I	73	Confident	79.5	Confident	61 Å²	61	58.8 Å²	58.8	31%	0.313	29%	0.294	S	S	.	.	H	α-helix	trans	-65	-41.1	176.6	-67.7	163.8	0	0	0	110.7	E212 L213 Y217 K218 C219 I279 V304	E212-I215 PolarHBondContact O-N 2.95Å; L213-I215 PolarHBondContact O-N 3.02Å; I215-Y217 VanDerWaalsContact C-N 3.3Å; I215-Y217 PolarHBondContact O-N 3.37Å; I215-K218 PolarHBondContact O-N 3.12Å; I215-C219 PolarHBondContact O-N 3.42Å; I215-C219 PolarHBondContact O-SG 3.37Å; I215-I279 HydrophobicContact CG2-CD1 3.34Å; I215-I279 HydrophobicContact CG2-CG1 4.07Å; I215-V304 HydrophobicContact CD1-CG2 3.78Å
216	L	76.3	Confident	80.5	Confident	15 Å²	15	58 Å²	58	8%	0.079	30%	0.295	C	S	.	.	H	α-helix	trans	-64.5	-38.2	176.5	-58.9	-178.3	0	0	0	111.2	L213 K218 C219 F227 F302	L213-L216 HydrophobicContact CD2-CD1 3.54Å; L213-L216 HydrophobicContact CD2-CG 4.46Å; L213-L216 WeakPolarHBondContact O-CB 3.41Å; L213-L216 PolarHBondContact O-N 3.29Å; L216-K218 VanDerWaalsContact C-N 3.28Å; L216-K218 PolarHBondContact O-N 3.26Å; L216-C219 WeakPolarHBondContact O-CB 3.17Å; L216-C219 PolarHBondContact O-N 3.31Å; L216-F227 HydrophobicContact CB-CB 4.2Å; L216-F227 HydrophobicContact CB-CD1 4.44Å; L216-F227 HydrophobicContact CB-CD2 4.14Å; L216-F227 HydrophobicContact CB-CG 4.02Å; L216-F227 HydrophobicContact CD1-CD2 4.24Å; L216-F227 HydrophobicContact CD1-CE2 4.45Å; L216-F302 HydrophobicContact CD2-CD1 4.36Å; L216-F302 HydrophobicContact CD2-CD2 4.02Å; L216-F302 HydrophobicContact CD2-CE1 3.73Å; L216-F302 HydrophobicContact CD2-CE2 3.36Å; L216-F302 HydrophobicContact CD2-CG 4.49Å; L216-F302 HydrophobicContact CD2-CZ 3.19Å
217	Y	78.4	Confident	81.5	Confident	120 Å²	120	56.7 Å²	56.7	47%	0.471	29%	0.288	S	S	.	.	H	α-helix	trans	-64.1	-32.2	178	-175.2	-93.6	0	0	0	113.1	I155 L213 E214 I215 C219 F227	I155-Y217 HydrophobicContact CD1-CE1 4.21Å; I155-Y217 HydrophobicContact CG2-CD1 4.25Å; I155-Y217 HydrophobicContact CG2-CE1 3.78Å; I155-Y217 HydrophobicContact CG2-CE2 4.14Å; L213-Y217 PolarHBondContact O-N 2.94Å; E214-Y217 PolarHBondContact O-N 3.37Å; I215-Y217 VanDerWaalsContact C-N 3.3Å; I215-Y217 PolarHBondContact O-N 3.37Å; Y217-C219 VanDerWaalsContact C-N 3.29Å; Y217-F227 AromaticContact CD2-CD1 3.99Å; Y217-F227 HydrophobicContact CD2-CD1 3.99Å; Y217-F227 HydrophobicContact CD2-CE1 4.13Å; Y217-F227 HydrophobicContact CG-CD1 4.46Å
218	K	77.6	Confident	82.3	Confident	126 Å²	126	53.1 Å²	53.1	55%	0.548	27%	0.271	S	S	.	.	T	Hydrogen-bonded Turn	trans	-79.3	-11.7	177.7	-69.2	173.4	-174.9	166	0	113.4	E214 I215 L216 D220	E214-K218 WeakPolarHBondContact O-CG 3.45Å; E214-K218 PolarHBondContact O-N 3.29Å; E214-K218 WeakPolarHBondContact OE1-CE 3.37Å; E214-K218 IonicContact OE1-NZ 2.61Å; E214-K218 PolarHBondContact OE1-NZ 3.04Å; I215-K218 PolarHBondContact O-N 3.12Å; L216-K218 VanDerWaalsContact C-N 3.28Å; L216-K218 PolarHBondContact O-N 3.26Å; K218-D220 PolarHBondContact O-N 2.82Å
219	C	85.1	Confident	83	Confident	16 Å²	16	48.2 Å²	48.2	11%	0.108	25%	0.25	C	C	.	.			trans	-75.4	112.5	178.6	-68.3	0	0	0	0	109.9	I215 L216 Y217 I224 Y273 F302	I215-C219 PolarHBondContact O-N 3.42Å; I215-C219 PolarHBondContact O-SG 3.37Å; L216-C219 WeakPolarHBondContact O-CB 3.17Å; L216-C219 PolarHBondContact O-N 3.31Å; Y217-C219 VanDerWaalsContact C-N 3.29Å; C219-I224 HydrophobicContact CB-CG2 4.11Å; C219-Y273 WeakPolarHBondContact CA-OH 3.35Å; C219-Y273 HydrophobicContact CB-CE1 4.19Å; C219-F302 HydrophobicContact CB-CZ 4.36Å
220	D	88.3	Confident	83.6	Confident	144 Å²	144	49.3 Å²	49.3	77%	0.77	26%	0.259	S	S	*	.			trans	-122.1	97.3	172.2	-175	17.8	0	0	0	109.2	K218 Y273	K218-D220 PolarHBondContact O-N 2.82Å; D220-Y273 PolarHBondContact N-OH 3.22Å; D220-Y273 WeakPolarHBondContact O-CE2 3.37Å; D220-Y273 PolarHBondContact O-OH 2.78Å
221	S	95	Very high	84.2	Confident	23 Å²	23	47.9 Å²	47.9	16%	0.161	25%	0.251	C	S	.	.			trans	-154.4	143.2	179.5	175.4	0	0	0	0	110.7	Y223 I224	S221-Y223 PolarHBondContact O-N 3.37Å; S221-Y223 VanDerWaalsContact O-N 3.16Å; S221-Y223 PolarHBondContact OG-N 2.93Å; S221-I224 PolarHBondContact O-N 3.26Å
222	S	96.3	Very high	84.8	Confident	80 Å²	80	46.5 Å²	46.5	56%	0.559	24%	0.236	S	C	*	.	T	Hydrogen-bonded Turn	trans	-67.9	-9.3	174.6	-66.8	0	0	0	0	113.8	K298	S222-K298 VanDerWaalsContact O-CE 3.27Å; S222-K298 WeakPolarHBondContact O-CE 3.29Å
223	Y	97.4	Very high	85.3	Confident	71 Å²	71	45.7 Å²	45.7	28%	0.278	23%	0.233	S	C	.	.	T	Hydrogen-bonded Turn	trans	-112.2	2.7	-177.1	-51.3	-73.1	0	0	0	113.2	S221 A266 K269 K298 L299	S221-Y223 PolarHBondContact O-N 3.37Å; S221-Y223 VanDerWaalsContact O-N 3.16Å; S221-Y223 PolarHBondContact OG-N 2.93Å; Y223-A266 HydrophobicContact CD1-CB 3.72Å; Y223-A266 HydrophobicContact CE1-CB 4.03Å; Y223-K269 HydrophobicContact CD1-CB 4.2Å; Y223-K269 HydrophobicContact CD2-CB 3.59Å; Y223-K269 HydrophobicContact CD2-CD 4.27Å; Y223-K269 HydrophobicContact CE1-CB 4.3Å; Y223-K269 HydrophobicContact CE1-CD 3.82Å; Y223-K269 HydrophobicContact CE2-CB 3.73Å; Y223-K269 HydrophobicContact CE2-CD 3.52Å; Y223-K269 HydrophobicContact CE2-CG 4.22Å; Y223-K269 HydrophobicContact CG-CB 3.84Å; Y223-K269 VanDerWaalsContact OH-CD 3.24Å; Y223-K269 WeakPolarHBondContact OH-CD 3.09Å; Y223-K269 PolarHBondContact OH-NZ 2.71Å; Y223-K298 WeakPolarHBondContact O-CA 3.15Å; Y223-L299 PolarHBondContact O-N 3.47Å
224	I	95.6	Very high	85.5	Confident	3 Å²	3	52.3 Å²	52.3	2%	0.015	26%	0.264	C	S	.	.	B	Isolated β-bridge	trans	-118.9	141.3	176.5	-57.1	-58.5	0	0	0	108.5	C219 S221 G226 Y273 L274 K298 L299 F302	C219-I224 HydrophobicContact CB-CG2 4.11Å; S221-I224 PolarHBondContact O-N 3.26Å; I224-G226 PolarHBondContact O-N 2.93Å; I224-Y273 HydrophobicContact CD1-CD1 4.39Å; I224-Y273 HydrophobicContact CG1-CD1 3.62Å; I224-Y273 HydrophobicContact CG1-CE1 4.08Å; I224-L274 HydrophobicContact CD1-CD1 3.96Å; I224-L274 HydrophobicContact CD1-CD2 3.93Å; I224-L274 HydrophobicContact CD1-CG 3.73Å; I224-L274 HydrophobicContact CG1-CD2 4.36Å; I224-K298 WeakPolarHBondContact O-CD 3.46Å; I224-L299 HydrophobicContact CD1-CB 4.09Å; I224-L299 HydrophobicContact CD1-CD1 4.46Å; I224-F302 HydrophobicContact CG2-CD1 4.27Å; I224-F302 HydrophobicContact CG2-CE1 3.29Å; I224-F302 HydrophobicContact CG2-CZ 3.51Å
225	I	94.2	Very high	85.9	Confident	11 Å²	11	54.4 Å²	54.4	6%	0.056	28%	0.276	C	S	.	.	P	Polyproline II helix	trans	-60.7	129	179.2	-160.9	69.4	0	0	0	110.6	F227 T241 E242 M244 L290 K298 L299 C300	I225-F227 PolarHBondContact O-N 3.43Å; I225-T241 HydrophobicContact CG1-CG2 4.45Å; I225-T241 HydrophobicContact CG2-CG2 4.43Å; I225-E242 HydrophobicContact CD1-CG 3.3Å; I225-E242 HydrophobicContact CG1-CG 3.92Å; I225-M244 HydrophobicContact CD1-CG 3.55Å; I225-M244 HydrophobicContact CD1-SD 4.26Å; I225-L290 HydrophobicContact CD1-CD1 3.75Å; I225-L290 HydrophobicContact CG1-CD1 4.33Å; I225-K298 HydrophobicContact CD1-CB 4.47Å; I225-K298 HydrophobicContact CD1-CD 4.45Å; I225-L299 WeakPolarHBondContact CB-O 3.34Å; I225-L299 PolarHBondContact N-O 3.42Å; I225-C300 HydrophobicContact CB-CB 3.97Å; I225-C300 HydrophobicContact CG1-CB 4.4Å; I225-C300 HydrophobicContact CG2-CB 3.7Å
226	G	91.6	Very high	86.4	Confident	22 Å²	22	55.1 Å²	55.1	23%	0.227	28%	0.275	C	S	.	.	P	Polyproline II helix	trans	-67.6	119.2	178	0	0	0	0	0	109.9	I224 T241 E242	I224-G226 PolarHBondContact O-N 2.93Å; G226-T241 CarbonylContact O-C 3.6Å; G226-T241 VanDerWaalsContact O-CA 3.23Å; G226-T241 WeakPolarHBondContact O-CA 3.44Å; G226-T241 WeakPolarHBondContact O-CB 3.26Å; G226-E242 PolarHBondContact N-OE1 3.11Å; G226-E242 PolarHBondContact O-N 3.35Å
227	F	89.4	Confident	86.8	Confident	31 Å²	31	54.4 Å²	54.4	14%	0.136	27%	0.271	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-92	129	175.8	176.5	-98.1	0	0	0	109.8	L213 L216 Y217 I225 G229 A230 I239 T241	L213-F227 HydrophobicContact CB-CZ 4.39Å; L216-F227 HydrophobicContact CB-CB 4.2Å; L216-F227 HydrophobicContact CB-CD1 4.44Å; L216-F227 HydrophobicContact CB-CD2 4.14Å; L216-F227 HydrophobicContact CB-CG 4.02Å; L216-F227 HydrophobicContact CD1-CD2 4.24Å; L216-F227 HydrophobicContact CD1-CE2 4.45Å; Y217-F227 AromaticContact CD2-CD1 3.99Å; Y217-F227 HydrophobicContact CD2-CD1 3.99Å; Y217-F227 HydrophobicContact CD2-CE1 4.13Å; Y217-F227 HydrophobicContact CG-CD1 4.46Å; I225-F227 PolarHBondContact O-N 3.43Å; F227-G229 WeakPolarHBondContact CE2-O 3.33Å; F227-A230 HydrophobicContact CE2-CB 4.34Å; F227-A230 HydrophobicContact CZ-CB 4.11Å; F227-I239 HydrophobicContact CD2-CG2 4.23Å; F227-I239 HydrophobicContact CE2-CG2 3.97Å; F227-T241 HydrophobicContact CD2-CG2 4.42Å
228	Y	87.4	Confident	87.2	Confident	74 Å²	74	48.8 Å²	48.8	29%	0.29	25%	0.25	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-105.5	-25.5	179.2	-61.3	-39.6	0	0	0	113.6	M161 L192 C240 E242	M161-Y228 HydrophobicContact CE-CG 4.4Å; L192-Y228 HydrophobicContact CD2-CD2 3.31Å; L192-Y228 HydrophobicContact CD2-CE2 3.34Å; L192-Y228 HydrophobicContact CG-CD2 4.49Å; Y228-C240 PolarHBondContact N-O 2.99Å; Y228-E242 HydrophobicContact CE2-CB 4Å; Y228-E242 WeakPolarHBondContact OH-CB 3.46Å
229	G	85.8	Confident	87.7	Confident	6 Å²	6	43.3 Å²	43.3	6%	0.062	23%	0.226	C	C	.	.	E	Extended strand (participates in β ladder)	trans	160.2	175.7	178.4	0	0	0	0	0	112.3	F227 C240	F227-G229 WeakPolarHBondContact CE2-O 3.33Å; G229-C240 PolarHBondContact N-O 3.33Å; G229-C240 WeakPolarHBondContact O-CA 3.27Å; G229-C240 WeakPolarHBondContact O-CB 3.45Å; G229-C240 PolarHBondContact O-N 3.23Å
230	A	85.5	Confident	88	Confident	22 Å²	22	42.5 Å²	42.5	18%	0.182	22%	0.221	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-142.7	151.3	170	0	0	0	0	0	109.7	L213 F227 I237 S238 I239	L213-A230 HydrophobicContact CD1-CB 3.59Å; F227-A230 HydrophobicContact CE2-CB 4.34Å; F227-A230 HydrophobicContact CZ-CB 4.11Å; A230-I237 HydrophobicContact CB-CD1 4.44Å; A230-S238 CarbonylContact C-O 3.41Å; A230-S238 WeakPolarHBondContact CA-O 3.44Å; A230-S238 WeakPolarHBondContact CB-O 3.45Å; A230-I239 HydrophobicContact CB-CG1 4.33Å
231	F	84.8	Confident	88.2	Confident	19 Å²	19	36.9 Å²	36.9	8%	0.083	19%	0.192	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-142.5	157.2	177.8	61.9	-92	0	0	0	110.8	M161 E163 I166 V233 S238	M161-F231 HydrophobicContact CB-CD1 4.19Å; M161-F231 WeakPolarHBondContact O-CB 3.5Å; M161-F231 WeakPolarHBondContact O-CD1 3.33Å; E163-F231 HydrophobicContact CB-CD2 4.09Å; E163-F231 HydrophobicContact CB-CE2 3.6Å; E163-F231 HydrophobicContact CB-CZ 4.23Å; E163-F231 HydrophobicContact CG-CE2 4.05Å; I166-F231 HydrophobicContact CG1-CE1 4.04Å; I166-F231 HydrophobicContact CG1-CZ 4.24Å; F231-V233 HydrophobicContact CD2-CG2 3.59Å; F231-V233 HydrophobicContact CE2-CG2 3.6Å; F231-S238 WeakPolarHBondContact CE2-OG 3.49Å; F231-S238 PolarHBondContact N-O 3.19Å; F231-S238 PolarHBondContact O-N 3.31Å
232	F	81.6	Confident	88.1	Confident	49 Å²	49	36.7 Å²	36.7	22%	0.215	19%	0.189	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-109.4	137	178.8	-63.4	-86.2	0	0	0	110.2	I201 Q206 I209 M210 R236 I237	I201-F232 HydrophobicContact CD1-CD1 3.64Å; I201-F232 HydrophobicContact CD1-CE1 4.12Å; Q206-F232 HydrophobicContact CB-CZ 4.43Å; Q206-F232 HydrophobicContact CG-CD1 4.12Å; Q206-F232 HydrophobicContact CG-CD2 3.85Å; Q206-F232 HydrophobicContact CG-CE1 3.75Å; Q206-F232 HydrophobicContact CG-CE2 3.45Å; Q206-F232 VanDerWaalsContact CG-CE2 3.45Å; Q206-F232 HydrophobicContact CG-CG 4.14Å; Q206-F232 HydrophobicContact CG-CZ 3.39Å; I209-F232 HydrophobicContact CB-CZ 4.29Å; I209-F232 HydrophobicContact CD1-CE1 4.37Å; I209-F232 HydrophobicContact CG2-CZ 4.06Å; M210-F232 HydrophobicContact CG-CE2 3.57Å; M210-F232 HydrophobicContact CG-CZ 3.98Å; M210-F232 HydrophobicContact SD-CE2 3.52Å; M210-F232 VanDerWaalsContact SD-CE2 3.52Å; M210-F232 HydrophobicContact SD-CZ 4.11Å; F232-R236 WeakPolarHBondContact CA-O 3.29Å; F232-I237 HydrophobicContact CD1-CB 3.84Å; F232-I237 HydrophobicContact CD1-CD1 4.41Å; F232-I237 HydrophobicContact CD1-CG1 4.1Å; F232-I237 HydrophobicContact CE1-CB 3.72Å; F232-I237 HydrophobicContact CE1-CD1 3.64Å; F232-I237 HydrophobicContact CE1-CG1 3.81Å; F232-I237 HydrophobicContact CE2-CD1 4.5Å; F232-I237 HydrophobicContact CZ-CD1 3.68Å; F232-I237 HydrophobicContact CZ-CG1 4.22Å
233	V	79.9	Confident	88.1	Confident	20 Å²	20	34.9 Å²	34.9	12%	0.121	17%	0.171	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-136.5	116.5	174.1	-176.5	0	0	0	0	107.1	E163 F231 N235 R236	E163-V233 HydrophobicContact CB-CG2 3.86Å; E163-V233 VanDerWaalsContact CD-CG2 3.48Å; E163-V233 HydrophobicContact CG-CG2 4.01Å; E163-V233 WeakPolarHBondContact OE2-CG1 3.36Å; E163-V233 WeakPolarHBondContact OE2-CG2 3.1Å; F231-V233 HydrophobicContact CD2-CG2 3.59Å; F231-V233 HydrophobicContact CE2-CG2 3.6Å; V233-N235 PolarHBondContact O-N 2.76Å; V233-R236 PolarHBondContact N-O 3.29Å; V233-R236 WeakPolarHBondContact O-CB 3.36Å; V233-R236 PolarHBondContact O-N 3.34Å
234	E	81.1	Confident	88.1	Confident	146 Å²	146	31.9 Å²	31.9	68%	0.682	16%	0.159	S	C	*	.	T	Hydrogen-bonded Turn	trans	51	-125.6	-175	-55.8	169.3	161.8	0	0	110.3	R236	E234-R236 VanDerWaalsContact C-N 3.31Å; E234-R236 PolarHBondContact O-N 2.68Å; E234-R236 IonicContact OE2-CZ 2.94Å; E234-R236 VanDerWaalsContact OE2-CZ 3.22Å; E234-R236 IonicContact OE2-NH1 2.81Å; E234-R236 PolarHBondContact OE2-NH1 3.35Å; E234-R236 IonicContact OE2-NH2 3.22Å; E234-R236 PolarHBondContact OE2-NH2 3.28Å
235	N	79.8	Confident	88.1	Confident	83 Å²	83	34.7 Å²	34.7	44%	0.444	17%	0.174	S	C	.	.	T	Hydrogen-bonded Turn	trans	-94.5	37.8	177	-82.6	26.4	0	0	0	111.8	L199 D200 V233	L199-N235 PolarHBondContact N-O 2.85Å; L199-N235 CarbonylContact O-C 3.55Å; L199-N235 VanDerWaalsContact O-C 3.3Å; L199-N235 WeakPolarHBondContact O-CA 3.4Å; L199-N235 WeakPolarHBondContact O-CB 3.13Å; D200-N235 PolarHBondContact OD1-ND2 3.32Å; V233-N235 PolarHBondContact O-N 2.76Å
236	R	82.8	Confident	88.2	Confident	76 Å²	76	34.3 Å²	34.3	29%	0.287	17%	0.173	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-135.2	142.1	179.1	-60.4	-177.1	-67.8	-80.9	-2.6	111.4	V196 I197 L198 F232 V233 E234	V196-R236 HydrophobicContact CG1-CB 4.18Å; V196-R236 HydrophobicContact CG1-CG 4.39Å; I197-R236 CarbonylContact O-C 3.5Å; I197-R236 VanDerWaalsContact O-CA 3.24Å; I197-R236 WeakPolarHBondContact O-CA 3.06Å; L198-R236 HydrophobicContact CD1-CG 4.15Å; L198-R236 HydrophobicContact CG-CG 3.99Å; F232-R236 WeakPolarHBondContact CA-O 3.29Å; V233-R236 PolarHBondContact N-O 3.29Å; V233-R236 WeakPolarHBondContact O-CB 3.36Å; V233-R236 PolarHBondContact O-N 3.34Å; E234-R236 VanDerWaalsContact C-N 3.31Å; E234-R236 PolarHBondContact O-N 2.68Å; E234-R236 IonicContact OE2-CZ 2.94Å; E234-R236 VanDerWaalsContact OE2-CZ 3.22Å; E234-R236 IonicContact OE2-NH1 2.81Å; E234-R236 PolarHBondContact OE2-NH1 3.35Å; E234-R236 IonicContact OE2-NH2 3.22Å; E234-R236 PolarHBondContact OE2-NH2 3.28Å
237	I	84.8	Confident	88.4	Confident	0 Å²	0	34.6 Å²	34.6	0%	0	18%	0.176	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-106.4	134.7	162.8	-174.8	170.7	0	0	0	109.8	V196 I197 L199 I209 L213 A230 F232 I239	V196-I237 WeakPolarHBondContact CA-O 3.31Å; I197-I237 HydrophobicContact CB-CG2 3.69Å; I197-I237 HydrophobicContact CD1-CG2 4.29Å; I197-I237 HydrophobicContact CG1-CG2 4.02Å; I197-I237 PolarHBondContact N-O 3.29Å; I197-I237 PolarHBondContact O-N 3.08Å; L199-I237 HydrophobicContact CD1-CB 4.14Å; L199-I237 HydrophobicContact CD1-CG2 3.41Å; L199-I237 VanDerWaalsContact CD1-CG2 3.41Å; L199-I237 HydrophobicContact CG-CG2 4.1Å; I209-I237 HydrophobicContact CG2-CD1 3.38Å; L213-I237 HydrophobicContact CD1-CD1 3.65Å; A230-I237 HydrophobicContact CB-CD1 4.44Å; F232-I237 HydrophobicContact CD1-CB 3.84Å; F232-I237 HydrophobicContact CD1-CD1 4.41Å; F232-I237 HydrophobicContact CD1-CG1 4.1Å; F232-I237 HydrophobicContact CE1-CB 3.72Å; F232-I237 HydrophobicContact CE1-CD1 3.64Å; F232-I237 HydrophobicContact CE1-CG1 3.81Å; F232-I237 HydrophobicContact CE2-CD1 4.5Å; F232-I237 HydrophobicContact CZ-CD1 3.68Å; F232-I237 HydrophobicContact CZ-CG1 4.22Å; I237-I239 HydrophobicContact CD1-CG1 4.34Å; I237-I239 HydrophobicContact CG1-CG1 4.3Å
238	S	88	Confident	88.6	Confident	3 Å²	3	34.2 Å²	34.2	2%	0.021	18%	0.177	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-111.3	120.3	172.6	-65.7	0	0	0	0	109.5	K195 A230 F231	K195-S238 CarbonylContact O-C 3.5Å; K195-S238 WeakPolarHBondContact O-CA 3.44Å; A230-S238 CarbonylContact C-O 3.41Å; A230-S238 WeakPolarHBondContact CA-O 3.44Å; A230-S238 WeakPolarHBondContact CB-O 3.45Å; F231-S238 WeakPolarHBondContact CE2-OG 3.49Å; F231-S238 PolarHBondContact N-O 3.19Å; F231-S238 PolarHBondContact O-N 3.31Å
239	I	88.3	Confident	89.1	Confident	10 Å²	10	30.7 Å²	30.7	5%	0.051	16%	0.163	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-103.9	120.6	177.4	-63.8	172.4	0	0	0	108.4	V194 K195 I197 L213 F227 A230 I237 T241	V194-I239 CarbonylContact C-O 3.4Å; V194-I239 WeakPolarHBondContact CA-O 3.42Å; K195-I239 HydrophobicContact CB-CB 4.42Å; K195-I239 PolarHBondContact N-O 3.44Å; K195-I239 PolarHBondContact O-N 3.41Å; I197-I239 HydrophobicContact CD1-CD1 4.2Å; L213-I239 HydrophobicContact CD1-CG1 4.45Å; L213-I239 HydrophobicContact CD2-CD1 4.04Å; L213-I239 HydrophobicContact CD2-CG1 4.45Å; F227-I239 HydrophobicContact CD2-CG2 4.23Å; F227-I239 HydrophobicContact CE2-CG2 3.97Å; A230-I239 HydrophobicContact CB-CG1 4.33Å; I237-I239 HydrophobicContact CD1-CG1 4.34Å; I237-I239 HydrophobicContact CG1-CG1 4.3Å; I239-T241 HydrophobicContact CG2-CG2 4.21Å
240	C	90.6	Very high	89.4	Confident	0 Å²	0	34.2 Å²	34.2	0%	0	18%	0.181	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-104.1	118.7	-176	-61.6	0	0	0	0	111	M161 L192 Y228 G229	M161-C240 HydrophobicContact CG-CB 4.34Å; L192-C240 HydrophobicContact CD1-CB 4.2Å; Y228-C240 PolarHBondContact N-O 2.99Å; G229-C240 PolarHBondContact N-O 3.33Å; G229-C240 WeakPolarHBondContact O-CA 3.27Å; G229-C240 WeakPolarHBondContact O-CB 3.45Å; G229-C240 PolarHBondContact O-N 3.23Å
241	T	92.3	Very high	89.6	Confident	26 Å²	26	35.7 Å²	35.7	16%	0.16	19%	0.188	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-127.6	169.7	178.8	58.1	0	0	0	0	111.7	L192 A193 I225 G226 F227 I239	L192-T241 WeakPolarHBondContact CA-O 3.43Å; A193-T241 PolarHBondContact N-O 3.17Å; A193-T241 PolarHBondContact O-N 3Å; A193-T241 PolarHBondContact O-OG1 2.88Å; I225-T241 HydrophobicContact CG1-CG2 4.45Å; I225-T241 HydrophobicContact CG2-CG2 4.43Å; G226-T241 CarbonylContact O-C 3.6Å; G226-T241 VanDerWaalsContact O-CA 3.23Å; G226-T241 WeakPolarHBondContact O-CA 3.44Å; G226-T241 WeakPolarHBondContact O-CB 3.26Å; F227-T241 HydrophobicContact CD2-CG2 4.42Å; I239-T241 HydrophobicContact CG2-CG2 4.21Å
242	E	93.6	Very high	89.8	Confident	19 Å²	19	36 Å²	36	9%	0.089	19%	0.188	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-59.4	143.8	170.5	76.7	-176	126.7	0	0	111.4	I225 G226 Y228 M244 K298	I225-E242 HydrophobicContact CD1-CG 3.3Å; I225-E242 HydrophobicContact CG1-CG 3.92Å; G226-E242 PolarHBondContact N-OE1 3.11Å; G226-E242 PolarHBondContact O-N 3.35Å; Y228-E242 HydrophobicContact CE2-CB 4Å; Y228-E242 WeakPolarHBondContact OH-CB 3.46Å; E242-M244 HydrophobicContact CG-CG 4.47Å; E242-M244 HydrophobicContact CG-SD 4.31Å; E242-K298 WeakPolarHBondContact OE1-CD 3.38Å; E242-K298 WeakPolarHBondContact OE1-CE 3.42Å; E242-K298 IonicContact OE1-NZ 2.8Å; E242-K298 PolarHBondContact OE1-NZ 2.92Å; E242-K298 IonicContact OE2-NZ 3.13Å; E242-K298 PolarHBondContact OE2-NZ 3.47Å
243	F	96.5	Very high	90	Very high	42 Å²	42	42.4 Å²	42.4	18%	0.184	21%	0.211	C	C	.	.			trans	-85.9	124.2	176.2	178.3	-113.8	0	0	0	111.1	L172 K182 I191 D245	L172-F243 HydrophobicContact CD1-CD2 3.86Å; L172-F243 HydrophobicContact CD1-CE2 3.6Å; L172-F243 HydrophobicContact CD2-CE2 3.8Å; L172-F243 HydrophobicContact CD2-CZ 4.42Å; L172-F243 HydrophobicContact CG-CE2 4.36Å; K182-F243 HydrophobicContact CD-CE1 4.34Å; K182-F243 HydrophobicContact CD-CE2 4.21Å; K182-F243 HydrophobicContact CD-CZ 3.97Å; K182-F243 HydrophobicContact CG-CD2 4.35Å; K182-F243 HydrophobicContact CG-CE2 4.19Å; K182-F243 HydrophobicContact CG-CZ 4.4Å; I191-F243 HydrophobicContact CB-CB 4.47Å; I191-F243 HydrophobicContact CG2-CB 3.85Å; I191-F243 HydrophobicContact CG2-CD1 3.65Å; I191-F243 HydrophobicContact CG2-CE1 4.39Å; I191-F243 HydrophobicContact CG2-CG 3.79Å; F243-D245 HydrophobicContact CD1-CB 4.22Å; F243-D245 HydrophobicContact CE1-CB 3.57Å; F243-D245 HydrophobicContact CZ-CB 4.16Å
244	M	97.1	Very high	90.6	Very high	8 Å²	8	46.9 Å²	46.9	4%	0.039	23%	0.229	C	C	.	.			trans	-103.5	103.4	175.4	-62.8	-66.8	-77.5	0	0	108.6	I225 E242 G246 G247 L290 N292 Q296 K298	I225-M244 HydrophobicContact CD1-CG 3.55Å; I225-M244 HydrophobicContact CD1-SD 4.26Å; E242-M244 HydrophobicContact CG-CG 4.47Å; E242-M244 HydrophobicContact CG-SD 4.31Å; M244-G246 PolarHBondContact O-N 2.83Å; M244-G247 PolarHBondContact O-N 3.03Å; M244-L290 HydrophobicContact CB-CB 3.85Å; M244-L290 HydrophobicContact CB-CD1 4.34Å; M244-L290 HydrophobicContact CE-CB 4.34Å; M244-L290 HydrophobicContact CG-CB 3.76Å; M244-L290 HydrophobicContact CG-CD1 4.05Å; M244-N292 HydrophobicContact CE-CB 3.96Å; M244-N292 HydrophobicContact SD-CB 4.13Å; M244-Q296 HydrophobicContact CE-CB 4.41Å; M244-Q296 WeakPolarHBondContact CE-O 3.39Å; M244-K298 HydrophobicContact CE-CB 4.16Å; M244-K298 HydrophobicContact CE-CD 4.12Å; M244-K298 HydrophobicContact CE-CG 3.97Å; M244-K298 HydrophobicContact SD-CD 4.14Å
245	D	95.6	Very high	91.3	Very high	62 Å²	62	40 Å²	40	33%	0.332	20%	0.197	S	C	.	.	T	Hydrogen-bonded Turn	trans	-72.7	-9.3	-169	66.8	-17	0	0	0	115.1	F243 N292 T293	F243-D245 HydrophobicContact CD1-CB 4.22Å; F243-D245 HydrophobicContact CE1-CB 3.57Å; F243-D245 HydrophobicContact CZ-CB 4.16Å; D245-N292 WeakPolarHBondContact OD1-CA 3.18Å; D245-N292 WeakPolarHBondContact OD1-CB 3.46Å; D245-T293 PolarHBondContact OD1-N 3.37Å; D245-T293 PolarHBondContact OD1-OG1 2.98Å; D245-T293 WeakPolarHBondContact OD2-CB 3.3Å; D245-T293 VanDerWaalsContact OD2-CG2 3.28Å; D245-T293 WeakPolarHBondContact OD2-CG2 3.25Å; D245-T293 PolarHBondContact OD2-OG1 3.41Å
246	G	95.9	Very high	92.1	Very high	3 Å²	3	38.4 Å²	38.4	3%	0.031	19%	0.191	C	C	.	.	T	Hydrogen-bonded Turn	trans	-88.6	-5.3	166.7	0	0	0	0	0	113.4	M244 Y252 V291	M244-G246 PolarHBondContact O-N 2.83Å; G246-Y252 WeakPolarHBondContact CA-OH 3.39Å; G246-Y252 WeakPolarHBondContact O-CE2 2.95Å; G246-Y252 PolarHBondContact O-OH 3.46Å; G246-V291 CarbonylContact C-O 3.59Å; G246-V291 VanDerWaalsContact C-O 3.31Å; G246-V291 WeakPolarHBondContact CA-O 3.33Å; G246-V291 PolarHBondContact N-O 2.98Å
247	G	95.1	Very high	92.8	Very high	28 Å²	28	36.5 Å²	36.5	29%	0.289	19%	0.185	S	C	.	.			trans	63.7	-158.3	-179.1	0	0	0	0	0	113.1	M244 L290 V291	M244-G247 PolarHBondContact O-N 3.03Å; G247-L290 CarbonylContact O-C 3.51Å; G247-L290 WeakPolarHBondContact O-CA 3.49Å; G247-V291 PolarHBondContact N-O 3.36Å; G247-V291 PolarHBondContact O-N 3.28Å
248	S	95.3	Very high	93.4	Very high	23 Å²	23	41 Å²	41	16%	0.161	21%	0.206	C	C	.	.	B	Isolated β-bridge	trans	-88.9	154.6	-177.5	50.3	0	0	0	0	113	D250 V251 Y252 S287 M289	S248-D250 VanDerWaalsContact C-N 3.29Å; S248-D250 WeakPolarHBondContact CB-OD1 3.44Å; S248-D250 PolarHBondContact O-N 2.9Å; S248-D250 PolarHBondContact OG-OD1 2.88Å; S248-V251 VanDerWaalsContact O-CG2 3.29Å; S248-V251 WeakPolarHBondContact O-CG2 3.47Å; S248-V251 PolarHBondContact O-N 3.49Å; S248-Y252 WeakPolarHBondContact O-CD2 3.41Å; S248-Y252 WeakPolarHBondContact O-CE2 3.2Å; S248-S287 WeakPolarHBondContact CB-O 3.46Å; S248-M289 CarbonylContact C-O 3.5Å; S248-M289 VanDerWaalsContact CA-O 3.29Å; S248-M289 WeakPolarHBondContact CA-O 3.28Å
249	L	95.9	Very high	93.8	Very high	0 Å²	0	40.8 Å²	40.8	0%	0	21%	0.205	C	C	.	.	G	3₁₀ helix	trans	-70.2	-21.1	-174.1	-68.5	-175.3	0	0	0	114.3	V251 Y252 M255 I263 P286 M289 V291 L349	L249-V251 PolarHBondContact O-N 2.87Å; L249-Y252 HydrophobicContact CD2-CD2 4.35Å; L249-Y252 HydrophobicContact CD2-CE2 4.44Å; L249-Y252 PolarHBondContact O-N 3.21Å; L249-M255 HydrophobicContact CB-CE 3.99Å; L249-M255 HydrophobicContact CD2-CE 3.82Å; L249-M255 HydrophobicContact CG-CE 4.33Å; L249-I263 HydrophobicContact CD1-CD1 4.3Å; L249-I263 HydrophobicContact CD1-CG2 3.5Å; L249-I263 HydrophobicContact CD2-CD1 4.17Å; L249-P286 HydrophobicContact CB-CB 4.12Å; L249-P286 WeakPolarHBondContact CB-O 3.43Å; L249-P286 PolarHBondContact N-O 3.46Å; L249-M289 HydrophobicContact CB-CB 4.29Å; L249-M289 HydrophobicContact CD1-CB 3.59Å; L249-M289 HydrophobicContact CD1-CG 4.42Å; L249-M289 HydrophobicContact CD1-SD 4.01Å; L249-M289 HydrophobicContact CG-CB 3.86Å; L249-M289 WeakPolarHBondContact CG-O 3.47Å; L249-M289 PolarHBondContact N-O 2.82Å; L249-V291 HydrophobicContact CD2-CB 4.11Å; L249-V291 HydrophobicContact CD2-CG1 4Å; L249-L349 HydrophobicContact CB-CD1 4.19Å; L249-L349 HydrophobicContact CB-CD2 4.35Å; L249-L349 HydrophobicContact CD1-CD1 3.94Å
250	D	92.3	Very high	94.3	Very high	79 Å²	79	40.3 Å²	40.3	42%	0.422	20%	0.202	S	C	.	.	G	3₁₀ helix	trans	-64.2	-22.9	176.8	66.4	-49.4	0	0	0	113.5	S248 Y252 P286 S287	S248-D250 VanDerWaalsContact C-N 3.29Å; S248-D250 WeakPolarHBondContact CB-OD1 3.44Å; S248-D250 PolarHBondContact O-N 2.9Å; S248-D250 PolarHBondContact OG-OD1 2.88Å; D250-Y252 PolarHBondContact O-N 3.17Å; D250-P286 HydrophobicContact CB-CB 3.93Å; D250-P286 PolarHBondContact N-O 3.24Å; D250-S287 WeakPolarHBondContact OD1-CA 3.39Å
251	V	90.1	Very high	94.6	Very high	54 Å²	54	40.3 Å²	40.3	33%	0.327	20%	0.202	S	C	.	.	G	3₁₀ helix	trans	-77.3	-10	179.4	-43.9	0	0	0	0	112.5	S248 L249 R441	S248-V251 VanDerWaalsContact O-CG2 3.29Å; S248-V251 WeakPolarHBondContact O-CG2 3.47Å; S248-V251 PolarHBondContact O-N 3.49Å; L249-V251 PolarHBondContact O-N 2.87Å; V251-R441 VanDerWaalsContact CB-NH1 3.34Å; V251-R441 PolarHBondContact O-NH1 3.42Å
252	Y	90.3	Very high	94.9	Very high	24 Å²	24	41 Å²	41	9%	0.094	20%	0.202	C	C	.	.	S	Bend	trans	-97	149.9	179.7	-61	-95.1	0	0	0	110.5	G246 S248 L249 D250 M255 V291 W433 A437	G246-Y252 WeakPolarHBondContact CA-OH 3.39Å; G246-Y252 WeakPolarHBondContact O-CE2 2.95Å; G246-Y252 PolarHBondContact O-OH 3.46Å; S248-Y252 WeakPolarHBondContact O-CD2 3.41Å; S248-Y252 WeakPolarHBondContact O-CE2 3.2Å; L249-Y252 HydrophobicContact CD2-CD2 4.35Å; L249-Y252 HydrophobicContact CD2-CE2 4.44Å; L249-Y252 PolarHBondContact O-N 3.21Å; D250-Y252 PolarHBondContact O-N 3.17Å; Y252-M255 HydrophobicContact CD2-CE 4.3Å; Y252-M255 HydrophobicContact CG-CE 4.06Å; Y252-V291 HydrophobicContact CE2-CG1 3.95Å; Y252-W433 AromaticContact CD1-CH2 3.32Å; Y252-W433 HydrophobicContact CD1-CH2 3.32Å; Y252-W433 HydrophobicContact CD1-CZ2 4.23Å; Y252-W433 AromaticContact CD1-CZ3 3.57Å; Y252-W433 HydrophobicContact CD1-CZ3 3.57Å; Y252-W433 HydrophobicContact CE1-CH2 4.07Å; Y252-W433 AromaticContact CE1-CZ3 3.83Å; Y252-W433 HydrophobicContact CE1-CZ3 3.83Å; Y252-W433 AromaticContact CG-CH2 3.66Å; Y252-W433 HydrophobicContact CG-CH2 3.66Å; Y252-W433 HydrophobicContact CG-CZ3 4.06Å; Y252-A437 HydrophobicContact CD1-CB 3.83Å; Y252-A437 HydrophobicContact CE1-CB 3.75Å
253	R	83.8	Confident	95.2	Very high	185 Å²	185	40.1 Å²	40.1	70%	0.698	20%	0.198	S	C	*	.			trans	-83.7	-159.1	176.2	-60.9	-175.7	-175.6	149.5	5.4	110.4	M255	R253-M255 WeakPolarHBondContact O-CG 3.09Å; R253-M255 PolarHBondContact O-N 3.38Å
254	K	93.4	Very high	95.2	Very high	113 Å²	113	38.1 Å²	38.1	49%	0.491	19%	0.189	S	C	.	.	S	Bend	trans	-44.8	121.7	172.6	-175.9	165	-176.5	171.6	0	111.1	L349 A350 E387	K254-L349 WeakPolarHBondContact CA-O 3.43Å; K254-A350 WeakPolarHBondContact CE-O 3.31Å; K254-A350 WeakPolarHBondContact CG-O 3.41Å; K254-E387 IonicContact NZ-OE2 3.95Å
255	M	95.6	Very high	95.3	Very high	3 Å²	3	38.1 Å²	38.1	2%	0.015	19%	0.19	C	C	.	.			trans	-102	140.4	179.3	-58.8	-166.9	-168.4	0	0	111	L249 Y252 R253 L260 I263 L349 W433	L249-M255 HydrophobicContact CB-CE 3.99Å; L249-M255 HydrophobicContact CD2-CE 3.82Å; L249-M255 HydrophobicContact CG-CE 4.33Å; Y252-M255 HydrophobicContact CD2-CE 4.3Å; Y252-M255 HydrophobicContact CG-CE 4.06Å; R253-M255 WeakPolarHBondContact O-CG 3.09Å; R253-M255 PolarHBondContact O-N 3.38Å; M255-L260 HydrophobicContact CB-CD1 4.01Å; M255-L260 HydrophobicContact CB-CD2 3.75Å; M255-L260 HydrophobicContact CB-CG 3.64Å; M255-L260 HydrophobicContact CG-CD2 4.21Å; M255-L260 HydrophobicContact SD-CD2 3.69Å; M255-I263 HydrophobicContact SD-CD1 3.9Å; M255-L349 HydrophobicContact CE-CD1 4.12Å; M255-L349 HydrophobicContact CE-CD2 3.51Å; M255-L349 HydrophobicContact CE-CG 4.26Å; M255-L349 HydrophobicContact CG-CB 4.47Å; M255-L349 PolarHBondContact N-O 2.9Å; M255-L349 HydrophobicContact SD-CB 4.41Å; M255-L349 HydrophobicContact SD-CD1 4.37Å; M255-L349 HydrophobicContact SD-CD2 4.43Å; M255-W433 HydrophobicContact CB-CH2 4.47Å; M255-W433 HydrophobicContact CB-CZ2 4.15Å; M255-W433 HydrophobicContact CE-CH2 3.71Å; M255-W433 HydrophobicContact CE-CZ3 4.26Å; M255-W433 HydrophobicContact CG-CH2 3.55Å; M255-W433 HydrophobicContact CG-CZ2 3.6Å; M255-W433 HydrophobicContact SD-CH2 3.57Å; M255-W433 VanDerWaalsContact SD-CH2 3.57Å; M255-W433 HydrophobicContact SD-CZ2 4.19Å; M255-W433 HydrophobicContact SD-CZ3 4.06Å
256	P	96.7	Very high	95.5	Very high	49 Å²	49	35.7 Å²	35.7	32%	0.318	18%	0.178	S	C	.	.			trans	-62.8	140.9	172.2	-21.8	33.6	0	0	0	111.9	H258 V259 L260	P256-H258 VanDerWaalsContact C-N 3.26Å; P256-H258 WeakPolarHBondContact CB-CE1 3.43Å; P256-H258 WeakPolarHBondContact CB-ND1 3.46Å; P256-H258 PolarHBondContact O-N 3.08Å; P256-V259 HydrophobicContact CB-CG2 4.39Å; P256-V259 HydrophobicContact CG-CG2 4.5Å; P256-V259 PolarHBondContact O-N 3.45Å; P256-L260 PolarHBondContact O-N 3.35Å
257	E	97.4	Very high	95.6	Very high	35 Å²	35	35.6 Å²	35.6	16%	0.164	18%	0.176	C	C	.	.	H	α-helix	trans	-55.1	-39.7	-177.3	-168.1	-172.2	124.4	0	0	112.9	V259 L260 G261 S389 F392 F418	E257-V259 VanDerWaalsContact C-N 3.27Å; E257-V259 PolarHBondContact O-N 2.87Å; E257-L260 CarbonylContact O-C 3.58Å; E257-L260 WeakPolarHBondContact O-CB 3.44Å; E257-L260 PolarHBondContact O-N 3.36Å; E257-G261 PolarHBondContact O-N 2.87Å; E257-S389 WeakPolarHBondContact OE1-CB 3.32Å; E257-S389 PolarHBondContact OE1-OG 3.39Å; E257-S389 PolarHBondContact OE2-N 3.11Å; E257-F392 HydrophobicContact CG-CB 4.11Å; E257-F392 HydrophobicContact CG-CD1 3.8Å; E257-F392 HydrophobicContact CG-CE1 4.41Å; E257-F392 HydrophobicContact CG-CG 3.93Å; E257-F418 HydrophobicContact CG-CE2 4.01Å; E257-F418 HydrophobicContact CG-CZ 4.43Å
258	H	96.8	Very high	95.8	Very high	94 Å²	94	34.2 Å²	34.2	44%	0.435	16%	0.163	S	C	.	.	H	α-helix	trans	-66.3	-27.1	179.9	70.7	-85.8	0	0	0	113.7	P256 R262 F422	P256-H258 VanDerWaalsContact C-N 3.26Å; P256-H258 WeakPolarHBondContact CB-CE1 3.43Å; P256-H258 WeakPolarHBondContact CB-ND1 3.46Å; P256-H258 PolarHBondContact O-N 3.08Å; H258-R262 PolarHBondContact O-NH1 3.11Å; H258-F422 HydrophobicContact CB-CE1 3.95Å; H258-F422 HydrophobicContact CB-CZ 4.42Å
259	V	98	Very high	95.9	Very high	0 Å²	0	35.4 Å²	35.4	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-78.3	-46.3	171.9	177.7	0	0	0	0	109	P256 E257 G261 R262 I263 V429 W433	P256-V259 HydrophobicContact CB-CG2 4.39Å; P256-V259 HydrophobicContact CG-CG2 4.5Å; P256-V259 PolarHBondContact O-N 3.45Å; E257-V259 VanDerWaalsContact C-N 3.27Å; E257-V259 PolarHBondContact O-N 2.87Å; V259-G261 VanDerWaalsContact C-N 3.31Å; V259-G261 PolarHBondContact O-N 3.16Å; V259-R262 PolarHBondContact O-N 3.3Å; V259-R262 VanDerWaalsContact O-N 3.11Å; V259-I263 HydrophobicContact CG1-CD1 3.91Å; V259-I263 HydrophobicContact CG1-CG1 4.39Å; V259-I263 WeakPolarHBondContact O-CG1 3.28Å; V259-I263 PolarHBondContact O-N 2.87Å; V259-I263 VanDerWaalsContact O-N 3.08Å; V259-V429 HydrophobicContact CG2-CG1 4.08Å; V259-W433 HydrophobicContact CB-CG 4.45Å; V259-W433 HydrophobicContact CG1-CB 4.28Å; V259-W433 HydrophobicContact CG1-CD2 3.91Å; V259-W433 HydrophobicContact CG1-CE3 3.94Å; V259-W433 HydrophobicContact CG1-CG 4.05Å; V259-W433 HydrophobicContact CG2-CB 3.9Å; V259-W433 HydrophobicContact CG2-CD2 4.43Å; V259-W433 HydrophobicContact CG2-CG 3.79Å
260	L	97.7	Very high	96	Very high	0 Å²	0	35.4 Å²	35.4	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-55.8	-43.2	176.6	-74.6	174.4	0	0	0	112.5	M255 P256 E257 R262 I263 A264 F346 L349 A350 F392	M255-L260 HydrophobicContact CB-CD1 4.01Å; M255-L260 HydrophobicContact CB-CD2 3.75Å; M255-L260 HydrophobicContact CB-CG 3.64Å; M255-L260 HydrophobicContact CG-CD2 4.21Å; M255-L260 HydrophobicContact SD-CD2 3.69Å; P256-L260 PolarHBondContact O-N 3.35Å; E257-L260 CarbonylContact O-C 3.58Å; E257-L260 WeakPolarHBondContact O-CB 3.44Å; E257-L260 PolarHBondContact O-N 3.36Å; L260-R262 VanDerWaalsContact C-N 3.26Å; L260-R262 PolarHBondContact O-N 2.89Å; L260-I263 CarbonylContact O-C 3.59Å; L260-I263 PolarHBondContact O-N 3.21Å; L260-I263 VanDerWaalsContact O-N 3.14Å; L260-A264 WeakPolarHBondContact O-CB 3.46Å; L260-A264 PolarHBondContact O-N 2.86Å; L260-F346 HydrophobicContact CB-CD1 4.3Å; L260-F346 HydrophobicContact CB-CE1 4.43Å; L260-F346 HydrophobicContact CD2-CD1 4.04Å; L260-F346 HydrophobicContact CD2-CE1 4.13Å; L260-F346 WeakPolarHBondContact O-CE1 3.44Å; L260-L349 HydrophobicContact CD2-CB 3.66Å; L260-L349 HydrophobicContact CD2-CD1 4.1Å; L260-A350 HydrophobicContact CD1-CB 3.66Å; L260-F392 HydrophobicContact CD1-CZ 4.38Å
261	G	98.1	Very high	96.2	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-56.2	-40.4	177.9	0	0	0	0	0	113.1	E257 V259 A264 V265 F418 F422	E257-G261 PolarHBondContact O-N 2.87Å; V259-G261 VanDerWaalsContact C-N 3.31Å; V259-G261 PolarHBondContact O-N 3.16Å; G261-A264 WeakPolarHBondContact O-CB 3.43Å; G261-A264 PolarHBondContact O-N 3.18Å; G261-V265 VanDerWaalsContact O-CG2 3.27Å; G261-V265 WeakPolarHBondContact O-CG2 3.37Å; G261-V265 PolarHBondContact O-N 2.74Å; G261-F418 VanDerWaalsContact CA-CZ 3.43Å; G261-F422 VanDerWaalsContact C-CB 3.43Å
262	R	98.3	Very high	96.6	Very high	41 Å²	41	30.7 Å²	30.7	16%	0.155	14%	0.139	C	C	.	.	H	α-helix	trans	-73.9	-35.5	178.1	-70.4	176.5	178.7	83	-3.6	112.6	H258 V259 L260 A264 A266 F422 D424 N426 V430	H258-R262 PolarHBondContact O-NH1 3.11Å; V259-R262 PolarHBondContact O-N 3.3Å; V259-R262 VanDerWaalsContact O-N 3.11Å; L260-R262 VanDerWaalsContact C-N 3.26Å; L260-R262 PolarHBondContact O-N 2.89Å; R262-A264 VanDerWaalsContact C-N 3.35Å; R262-A266 PolarHBondContact O-N 3.26Å; R262-F422 HydrophobicContact CG-CB 4.2Å; R262-F422 HydrophobicContact CG-CD1 4.47Å; R262-D424 IonicContact CZ-OD1 3.15Å; R262-D424 IonicContact CZ-OD2 3.56Å; R262-D424 VanDerWaalsContact CZ-OD2 3.3Å; R262-D424 IonicContact NE-OD1 2.88Å; R262-D424 PolarHBondContact NE-OD1 3.35Å; R262-D424 VanDerWaalsContact NE-OD1 3.15Å; R262-D424 IonicContact NE-OD2 2.74Å; R262-D424 PolarHBondContact NE-OD2 3.12Å; R262-D424 IonicContact NH2-OD1 3.2Å; R262-D424 IonicContact NH2-OD2 2.7Å; R262-D424 PolarHBondContact NH2-OD2 3Å; R262-N426 WeakPolarHBondContact CD-O 3.37Å; R262-V430 HydrophobicContact CB-CG2 3.77Å
263	I	98.4	Very high	96.8	Very high	0 Å²	0	31.9 Å²	31.9	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-64.4	-42.7	171	-61.7	175.7	0	0	0	109.8	L249 M255 V259 L260 V265 A266 V267 V297 F346 V430	L249-I263 HydrophobicContact CD1-CD1 4.3Å; L249-I263 HydrophobicContact CD1-CG2 3.5Å; L249-I263 HydrophobicContact CD2-CD1 4.17Å; M255-I263 HydrophobicContact SD-CD1 3.9Å; V259-I263 HydrophobicContact CG1-CD1 3.91Å; V259-I263 HydrophobicContact CG1-CG1 4.39Å; V259-I263 WeakPolarHBondContact O-CG1 3.28Å; V259-I263 PolarHBondContact O-N 2.87Å; V259-I263 VanDerWaalsContact O-N 3.08Å; L260-I263 CarbonylContact O-C 3.59Å; L260-I263 PolarHBondContact O-N 3.21Å; L260-I263 VanDerWaalsContact O-N 3.14Å; I263-V265 VanDerWaalsContact C-N 3.34Å; I263-V265 PolarHBondContact O-N 2.66Å; I263-A266 WeakPolarHBondContact O-CB 3.35Å; I263-A266 PolarHBondContact O-N 2.74Å; I263-A266 VanDerWaalsContact O-N 3.12Å; I263-V267 HydrophobicContact CG2-CG2 4.28Å; I263-V267 WeakPolarHBondContact O-CG2 3.13Å; I263-V267 PolarHBondContact O-N 2.66Å; I263-V297 HydrophobicContact CB-CG2 4.43Å; I263-V297 HydrophobicContact CG1-CG2 4.01Å; I263-V297 HydrophobicContact CG2-CG1 3.91Å; I263-V297 HydrophobicContact CG2-CG2 4.31Å; I263-F346 HydrophobicContact CB-CE1 4.26Å; I263-F346 HydrophobicContact CB-CZ 4.31Å; I263-F346 HydrophobicContact CG2-CE1 4.17Å; I263-F346 HydrophobicContact CG2-CZ 3.81Å; I263-V430 HydrophobicContact CG1-CG1 4.35Å; I263-V430 HydrophobicContact CG1-CG2 4.3Å
264	A	98.4	Very high	97.2	Very high	0 Å²	0	23.1 Å²	23.1	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-59.6	-44.3	178.4	0	0	0	0	0	111.1	L260 G261 R262 A266 V267 V268 F346 F418 I419	L260-A264 WeakPolarHBondContact O-CB 3.46Å; L260-A264 PolarHBondContact O-N 2.86Å; G261-A264 WeakPolarHBondContact O-CB 3.43Å; G261-A264 PolarHBondContact O-N 3.18Å; R262-A264 VanDerWaalsContact C-N 3.35Å; A264-A266 VanDerWaalsContact C-N 3.31Å; A264-A266 PolarHBondContact O-N 2.83Å; A264-V267 PolarHBondContact O-N 3.01Å; A264-V268 WeakPolarHBondContact O-CB 3.49Å; A264-V268 VanDerWaalsContact O-CG2 3.26Å; A264-V268 WeakPolarHBondContact O-CG2 3.33Å; A264-V268 PolarHBondContact O-N 2.78Å; A264-F346 HydrophobicContact CB-CD1 4.02Å; A264-F346 HydrophobicContact CB-CE1 3.45Å; A264-F346 VanDerWaalsContact CB-CE1 3.45Å; A264-F346 HydrophobicContact CB-CZ 3.76Å; A264-F418 HydrophobicContact CB-CE1 4.02Å; A264-I419 HydrophobicContact CB-CD1 3.74Å
265	V	98.7	Very high	97.1	Very high	8 Å²	8	21 Å²	21	5%	0.048	10%	0.1	C	C	.	.	H	α-helix	trans	-54.7	-47.9	174	170.5	0	0	0	0	111.3	G261 I263 K269 I419 F422 N423	G261-V265 VanDerWaalsContact O-CG2 3.27Å; G261-V265 WeakPolarHBondContact O-CG2 3.37Å; G261-V265 PolarHBondContact O-N 2.74Å; I263-V265 VanDerWaalsContact C-N 3.34Å; I263-V265 PolarHBondContact O-N 2.66Å; V265-K269 HydrophobicContact CG1-CD 4.14Å; V265-K269 WeakPolarHBondContact O-CB 3.43Å; V265-K269 VanDerWaalsContact O-CG 3.26Å; V265-K269 WeakPolarHBondContact O-CG 3.45Å; V265-K269 PolarHBondContact O-N 3.15Å; V265-I419 HydrophobicContact CG2-CG2 4Å; V265-I419 WeakPolarHBondContact CG2-O 3.35Å; V265-F422 HydrophobicContact CG2-CB 4.16Å; V265-N423 HydrophobicContact CG1-CB 4Å; V265-N423 WeakPolarHBondContact CG1-OD1 3.37Å; V265-N423 HydrophobicContact CG2-CB 3.99Å
266	A	98.5	Very high	96.9	Very high	10 Å²	10	24.4 Å²	24.4	8%	0.083	12%	0.124	C	C	.	.	H	α-helix	trans	-65.5	-43	-179.9	0	0	0	0	0	112.3	Y223 R262 I263 A264 K269 G270 V297	Y223-A266 HydrophobicContact CD1-CB 3.72Å; Y223-A266 HydrophobicContact CE1-CB 4.03Å; R262-A266 PolarHBondContact O-N 3.26Å; I263-A266 WeakPolarHBondContact O-CB 3.35Å; I263-A266 PolarHBondContact O-N 2.74Å; I263-A266 VanDerWaalsContact O-N 3.12Å; A264-A266 VanDerWaalsContact C-N 3.31Å; A264-A266 PolarHBondContact O-N 2.83Å; A266-K269 PolarHBondContact O-N 2.67Å; A266-G270 PolarHBondContact O-N 3.05Å; A266-V297 HydrophobicContact CB-CB 3.59Å; A266-V297 HydrophobicContact CB-CG1 3.92Å; A266-V297 HydrophobicContact CB-CG2 4.38Å
267	V	98.5	Very high	96.5	Very high	1 Å²	1	25.6 Å²	25.6	1%	0.006	13%	0.127	C	C	.	.	H	α-helix	trans	-65.6	-45.2	178.5	175.1	0	0	0	0	111.4	I263 A264 K269 G270 L271 M289 V297 L299 L342 F346	I263-V267 HydrophobicContact CG2-CG2 4.28Å; I263-V267 WeakPolarHBondContact O-CG2 3.13Å; I263-V267 PolarHBondContact O-N 2.66Å; A264-V267 PolarHBondContact O-N 3.01Å; V267-K269 PolarHBondContact O-N 3.17Å; V267-G270 WeakPolarHBondContact O-CA 3.49Å; V267-G270 PolarHBondContact O-N 3.33Å; V267-G270 VanDerWaalsContact O-N 3.11Å; V267-L271 HydrophobicContact CG1-CD1 4.32Å; V267-L271 HydrophobicContact CG1-CG 4.47Å; V267-L271 WeakPolarHBondContact O-CG 3.49Å; V267-L271 PolarHBondContact O-N 2.85Å; V267-M289 HydrophobicContact CG1-CE 4.13Å; V267-M289 HydrophobicContact CG2-CE 4.46Å; V267-M289 HydrophobicContact CG2-CG 4.17Å; V267-M289 HydrophobicContact CG2-SD 3.92Å; V267-V297 HydrophobicContact CG2-CG1 4.12Å; V267-L299 HydrophobicContact CG1-CD1 4.32Å; V267-L299 HydrophobicContact CG1-CD2 4.12Å; V267-L342 HydrophobicContact CB-CD1 4.19Å; V267-L342 HydrophobicContact CG1-CD1 3.41Å; V267-L342 VanDerWaalsContact CG1-CD1 3.41Å; V267-F346 HydrophobicContact CB-CE2 4.38Å; V267-F346 HydrophobicContact CB-CZ 4.44Å; V267-F346 HydrophobicContact CG1-CE2 4.48Å; V267-F346 HydrophobicContact CG2-CE2 4.27Å; V267-F346 HydrophobicContact CG2-CZ 4.17Å
268	V	98.5	Very high	95.9	Very high	0 Å²	0	30.2 Å²	30.2	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-61.5	-44.3	176.8	176.2	0	0	0	0	110.2	A264 G270 L271 T272 L342 F395 P410 L413 M414 I419	A264-V268 WeakPolarHBondContact O-CB 3.49Å; A264-V268 VanDerWaalsContact O-CG2 3.26Å; A264-V268 WeakPolarHBondContact O-CG2 3.33Å; A264-V268 PolarHBondContact O-N 2.78Å; V268-G270 VanDerWaalsContact C-N 3.29Å; V268-G270 PolarHBondContact O-N 2.85Å; V268-L271 PolarHBondContact O-N 3.4Å; V268-T272 WeakPolarHBondContact O-CB 3.34Å; V268-T272 PolarHBondContact O-N 2.9Å; V268-T272 PolarHBondContact O-OG1 3.42Å; V268-L342 HydrophobicContact CG2-CD2 3.88Å; V268-F395 HydrophobicContact CG2-CZ 4.37Å; V268-P410 WeakPolarHBondContact CG1-O 3.4Å; V268-L413 HydrophobicContact CG1-CB 3.82Å; V268-L413 HydrophobicContact CG2-CB 4.42Å; V268-L413 HydrophobicContact CG2-CD1 4.39Å; V268-M414 HydrophobicContact CB-SD 4.19Å; V268-M414 HydrophobicContact CG1-CG 3.91Å; V268-M414 HydrophobicContact CG1-SD 3.54Å; V268-M414 VanDerWaalsContact CG1-SD 3.54Å; V268-I419 HydrophobicContact CG2-CD1 4Å
269	K	98.4	Very high	95.4	Very high	47 Å²	47	26.9 Å²	26.9	20%	0.204	13%	0.132	C	C	.	.	H	α-helix	trans	-59.6	-38	173.4	-73.4	177.1	-175.6	171	0	112.7	Y223 V265 A266 V267 Y273 M414 N423	Y223-K269 HydrophobicContact CD1-CB 4.2Å; Y223-K269 HydrophobicContact CD2-CB 3.59Å; Y223-K269 HydrophobicContact CD2-CD 4.27Å; Y223-K269 HydrophobicContact CE1-CB 4.3Å; Y223-K269 HydrophobicContact CE1-CD 3.82Å; Y223-K269 HydrophobicContact CE2-CB 3.73Å; Y223-K269 HydrophobicContact CE2-CD 3.52Å; Y223-K269 HydrophobicContact CE2-CG 4.22Å; Y223-K269 HydrophobicContact CG-CB 3.84Å; Y223-K269 VanDerWaalsContact OH-CD 3.24Å; Y223-K269 WeakPolarHBondContact OH-CD 3.09Å; Y223-K269 PolarHBondContact OH-NZ 2.71Å; V265-K269 HydrophobicContact CG1-CD 4.14Å; V265-K269 WeakPolarHBondContact O-CB 3.43Å; V265-K269 VanDerWaalsContact O-CG 3.26Å; V265-K269 WeakPolarHBondContact O-CG 3.45Å; V265-K269 PolarHBondContact O-N 3.15Å; A266-K269 PolarHBondContact O-N 2.67Å; V267-K269 PolarHBondContact O-N 3.17Å; K269-Y273 WeakPolarHBondContact O-CB 3.42Å; K269-Y273 PolarHBondContact O-N 3.36Å; K269-M414 HydrophobicContact CD-CE 4.44Å; K269-M414 HydrophobicContact CG-CE 3.81Å; K269-M414 HydrophobicContact CG-SD 3.78Å; K269-N423 WeakPolarHBondContact CE-OD1 3.47Å; K269-N423 PolarHBondContact NZ-OD1 2.9Å
270	G	97.6	Very high	94.9	Very high	0 Å²	0	28 Å²	28	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-62.6	-47	173.2	0	0	0	0	0	112.6	A266 V267 V268 Y273 L274	A266-G270 PolarHBondContact O-N 3.05Å; V267-G270 WeakPolarHBondContact O-CA 3.49Å; V267-G270 PolarHBondContact O-N 3.33Å; V267-G270 VanDerWaalsContact O-N 3.11Å; V268-G270 VanDerWaalsContact C-N 3.29Å; V268-G270 PolarHBondContact O-N 2.85Å; G270-Y273 WeakPolarHBondContact O-CB 3.12Å; G270-Y273 PolarHBondContact O-N 3.32Å; G270-L274 WeakPolarHBondContact O-CG 3.33Å; G270-L274 PolarHBondContact O-N 3.44Å
271	L	97.3	Very high	94.5	Very high	2 Å²	2	28 Å²	28	1%	0.01	14%	0.138	C	C	.	.	H	α-helix	trans	-65.3	-42.9	177.4	-67.4	177.6	0	0	0	112.3	V267 V268 Y273 L274 W275 H281 V284 L299 D338 L342 P410	V267-L271 HydrophobicContact CG1-CD1 4.32Å; V267-L271 HydrophobicContact CG1-CG 4.47Å; V267-L271 WeakPolarHBondContact O-CG 3.49Å; V267-L271 PolarHBondContact O-N 2.85Å; V268-L271 PolarHBondContact O-N 3.4Å; L271-Y273 VanDerWaalsContact C-N 3.32Å; L271-Y273 PolarHBondContact O-N 2.93Å; L271-L274 PolarHBondContact O-N 2.77Å; L271-W275 VanDerWaalsContact O-CB 3.31Å; L271-W275 WeakPolarHBondContact O-CB 3.38Å; L271-W275 PolarHBondContact O-N 3.33Å; L271-H281 HydrophobicContact CD2-CB 4.02Å; L271-V284 HydrophobicContact CD2-CG2 3.84Å; L271-L299 HydrophobicContact CD2-CD1 3.9Å; L271-L299 HydrophobicContact CG-CD1 4.03Å; L271-D338 HydrophobicContact CD2-CB 4.24Å; L271-L342 HydrophobicContact CD1-CB 4.5Å; L271-L342 HydrophobicContact CD1-CD2 4.32Å; L271-P410 HydrophobicContact CB-CB 4.1Å; L271-P410 HydrophobicContact CB-CG 4.05Å
272	T	97.2	Very high	94.1	Very high	32 Å²	32	31 Å²	31	20%	0.196	15%	0.149	C	C	.	.	H	α-helix	trans	-57.8	-44.4	172.2	-62.2	0	0	0	0	111.2	V268 W275 S276 P410 E411	V268-T272 WeakPolarHBondContact O-CB 3.34Å; V268-T272 PolarHBondContact O-N 2.9Å; V268-T272 PolarHBondContact O-OG1 3.42Å; T272-W275 PolarHBondContact O-N 3.43Å; T272-S276 PolarHBondContact O-N 2.8Å; T272-P410 WeakPolarHBondContact OG1-CB 3.24Å; T272-P410 PolarHBondContact OG1-O 3.46Å; T272-E411 HydrophobicContact CG2-CG 4.13Å
273	Y	95.9	Very high	93.6	Very high	50 Å²	50	30 Å²	30	20%	0.196	15%	0.146	C	C	.	.	H	α-helix	trans	-60.8	-50.8	176.8	175.9	-95.7	0	0	0	111.8	C219 D220 I224 K269 G270 L271 W275 S276 L277	C219-Y273 WeakPolarHBondContact CA-OH 3.35Å; C219-Y273 HydrophobicContact CB-CE1 4.19Å; D220-Y273 PolarHBondContact N-OH 3.22Å; D220-Y273 WeakPolarHBondContact O-CE2 3.37Å; D220-Y273 PolarHBondContact O-OH 2.78Å; I224-Y273 HydrophobicContact CD1-CD1 4.39Å; I224-Y273 HydrophobicContact CG1-CD1 3.62Å; I224-Y273 HydrophobicContact CG1-CE1 4.08Å; K269-Y273 WeakPolarHBondContact O-CB 3.42Å; K269-Y273 PolarHBondContact O-N 3.36Å; G270-Y273 WeakPolarHBondContact O-CB 3.12Å; G270-Y273 PolarHBondContact O-N 3.32Å; L271-Y273 VanDerWaalsContact C-N 3.32Å; L271-Y273 PolarHBondContact O-N 2.93Å; Y273-W275 VanDerWaalsContact C-N 3.28Å; Y273-W275 PolarHBondContact O-N 2.92Å; Y273-S276 WeakPolarHBondContact O-CB 3.26Å; Y273-S276 PolarHBondContact O-N 3.13Å; Y273-S276 PolarHBondContact O-OG 3.17Å; Y273-L277 HydrophobicContact CD1-CD1 4.41Å; Y273-L277 HydrophobicContact CE1-CD1 3.66Å; Y273-L277 PolarHBondContact O-N 3.01Å
274	L	92.3	Very high	93.4	Very high	1 Å²	1	30 Å²	30	1%	0.005	15%	0.147	C	C	.	.	H	α-helix	trans	-59.8	-41.5	177.7	-68.3	176.9	0	0	0	111.4	I224 G270 L271 S276 L277 K278 I279 H281 F302	I224-L274 HydrophobicContact CD1-CD1 3.96Å; I224-L274 HydrophobicContact CD1-CD2 3.93Å; I224-L274 HydrophobicContact CD1-CG 3.73Å; I224-L274 HydrophobicContact CG1-CD2 4.36Å; G270-L274 WeakPolarHBondContact O-CG 3.33Å; G270-L274 PolarHBondContact O-N 3.44Å; L271-L274 PolarHBondContact O-N 2.77Å; L274-S276 VanDerWaalsContact C-N 3.34Å; L274-S276 PolarHBondContact O-N 3.01Å; L274-L277 CarbonylContact O-C 3.59Å; L274-L277 WeakPolarHBondContact O-CA 3.46Å; L274-L277 WeakPolarHBondContact O-CB 3.32Å; L274-L277 PolarHBondContact O-N 3.25Å; L274-L277 VanDerWaalsContact O-N 3.08Å; L274-K278 PolarHBondContact O-N 3.45Å; L274-K278 VanDerWaalsContact O-N 3.16Å; L274-I279 CarbonylContact C-O 3.54Å; L274-I279 HydrophobicContact CB-CB 4.24Å; L274-I279 HydrophobicContact CD2-CB 4.37Å; L274-I279 HydrophobicContact CD2-CD1 4.43Å; L274-I279 HydrophobicContact CD2-CG2 4.19Å; L274-I279 PolarHBondContact O-N 3.26Å; L274-H281 HydrophobicContact CD1-CB 4.25Å; L274-F302 HydrophobicContact CD1-CB 4.09Å; L274-F302 HydrophobicContact CD1-CD2 4.04Å; L274-F302 HydrophobicContact CD1-CG 4.01Å; L274-F302 HydrophobicContact CD2-CD2 3.64Å; L274-F302 HydrophobicContact CD2-CE2 3.48Å; L274-F302 VanDerWaalsContact CD2-CE2 3.48Å; L274-F302 HydrophobicContact CD2-CG 4.29Å; L274-F302 HydrophobicContact CD2-CZ 4.02Å
275	W	91.6	Very high	93.2	Very high	68 Å²	68	31 Å²	31	26%	0.258	15%	0.151	S	C	.	.	H	α-helix	trans	-67.7	-32.5	179.3	-175	-126.9	0	0	0	113.4	L271 T272 Y273 L277 K278 L280 I335 E411	L271-W275 VanDerWaalsContact O-CB 3.31Å; L271-W275 WeakPolarHBondContact O-CB 3.38Å; L271-W275 PolarHBondContact O-N 3.33Å; T272-W275 PolarHBondContact O-N 3.43Å; Y273-W275 VanDerWaalsContact C-N 3.28Å; Y273-W275 PolarHBondContact O-N 2.92Å; W275-L277 PolarHBondContact O-N 3.43Å; W275-K278 HydrophobicContact CH2-CD 4.48Å; W275-K278 HydrophobicContact CZ3-CD 4.42Å; W275-K278 WeakPolarHBondContact O-CA 3.33Å; W275-K278 PolarHBondContact O-N 3.01Å; W275-L280 HydrophobicContact CE3-CD2 3.95Å; W275-L280 HydrophobicContact CZ3-CD2 3.76Å; W275-I335 HydrophobicContact CB-CD1 3.9Å; W275-I335 HydrophobicContact CB-CG1 4.14Å; W275-I335 HydrophobicContact CD2-CB 3.85Å; W275-I335 HydrophobicContact CD2-CD1 4.19Å; W275-I335 HydrophobicContact CD2-CG1 3.88Å; W275-I335 HydrophobicContact CD2-CG2 4.2Å; W275-I335 HydrophobicContact CE3-CB 3.86Å; W275-I335 HydrophobicContact CE3-CD1 4.14Å; W275-I335 HydrophobicContact CE3-CG1 4.14Å; W275-I335 HydrophobicContact CG-CB 4.36Å; W275-I335 HydrophobicContact CG-CD1 4.1Å; W275-I335 HydrophobicContact CG-CG1 3.86Å; W275-I335 HydrophobicContact CH2-CB 4.35Å; W275-I335 HydrophobicContact CH2-CG2 4.38Å; W275-I335 HydrophobicContact CZ2-CB 4.34Å; W275-I335 HydrophobicContact CZ2-CG2 4.01Å; W275-I335 HydrophobicContact CZ3-CB 4.12Å; W275-E411 VanDerWaalsContact CD1-OE1 3.24Å; W275-E411 VanDerWaalsContact CD1-OE2 3.27Å
276	S	91.2	Very high	93	Very high	75 Å²	75	30.7 Å²	30.7	52%	0.524	15%	0.149	S	C	.	.	H	α-helix	trans	-60.2	-32.3	171.5	82.4	0	0	0	0	112	T272 Y273 L274 K278	T272-S276 PolarHBondContact O-N 2.8Å; Y273-S276 WeakPolarHBondContact O-CB 3.26Å; Y273-S276 PolarHBondContact O-N 3.13Å; Y273-S276 PolarHBondContact O-OG 3.17Å; L274-S276 VanDerWaalsContact C-N 3.34Å; L274-S276 PolarHBondContact O-N 3.01Å; S276-K278 VanDerWaalsContact C-N 3.31Å
277	L	87.7	Confident	92.7	Very high	73 Å²	73	32.1 Å²	32.1	38%	0.382	16%	0.159	S	C	.	.	T	Hydrogen-bonded Turn	trans	-87.7	3.5	173.6	-58.5	-179.5	0	0	0	113.3	Y273 L274 W275 I279	Y273-L277 HydrophobicContact CD1-CD1 4.41Å; Y273-L277 HydrophobicContact CE1-CD1 3.66Å; Y273-L277 PolarHBondContact O-N 3.01Å; L274-L277 CarbonylContact O-C 3.59Å; L274-L277 WeakPolarHBondContact O-CA 3.46Å; L274-L277 WeakPolarHBondContact O-CB 3.32Å; L274-L277 PolarHBondContact O-N 3.25Å; L274-L277 VanDerWaalsContact O-N 3.08Å; W275-L277 PolarHBondContact O-N 3.43Å; L277-I279 HydrophobicContact CB-CD1 3.77Å; L277-I279 HydrophobicContact CB-CG1 4.1Å; L277-I279 HydrophobicContact CD1-CD1 4.09Å; L277-I279 PolarHBondContact O-N 2.94Å
278	K	85.4	Confident	92.5	Very high	132 Å²	132	32.5 Å²	32.5	57%	0.574	16%	0.161	S	C	*	.	T	Hydrogen-bonded Turn	trans	58.9	30.7	-174.6	-53.3	-60.9	171	-159.1	0	114	L274 W275 S276	L274-K278 PolarHBondContact O-N 3.45Å; L274-K278 VanDerWaalsContact O-N 3.16Å; W275-K278 HydrophobicContact CH2-CD 4.48Å; W275-K278 HydrophobicContact CZ3-CD 4.42Å; W275-K278 WeakPolarHBondContact O-CA 3.33Å; W275-K278 PolarHBondContact O-N 3.01Å; S276-K278 VanDerWaalsContact C-N 3.31Å
279	I	85.3	Confident	92.4	Very high	24 Å²	24	32.5 Å²	32.5	12%	0.123	16%	0.161	C	C	.	.			trans	-98	129	173.8	-60	163.6	0	0	0	108.3	I215 L274 L277 F302	I215-I279 HydrophobicContact CG2-CD1 3.34Å; I215-I279 HydrophobicContact CG2-CG1 4.07Å; L274-I279 CarbonylContact C-O 3.54Å; L274-I279 HydrophobicContact CB-CB 4.24Å; L274-I279 HydrophobicContact CD2-CB 4.37Å; L274-I279 HydrophobicContact CD2-CD1 4.43Å; L274-I279 HydrophobicContact CD2-CG2 4.19Å; L274-I279 PolarHBondContact O-N 3.26Å; L277-I279 HydrophobicContact CB-CD1 3.77Å; L277-I279 HydrophobicContact CB-CG1 4.1Å; L277-I279 HydrophobicContact CD1-CD1 4.09Å; L277-I279 PolarHBondContact O-N 2.94Å; I279-F302 HydrophobicContact CG2-CD2 4.06Å; I279-F302 HydrophobicContact CG2-CE2 4.47Å
280	L	86.9	Confident	92.4	Very high	24 Å²	24	31.7 Å²	31.7	13%	0.126	16%	0.158	C	C	.	.			trans	-91.6	141.5	167.7	-60.2	179.1	0	0	0	108.9	W275 R282 G303 Y333 I335	W275-L280 HydrophobicContact CE3-CD2 3.95Å; W275-L280 HydrophobicContact CZ3-CD2 3.76Å; L280-R282 HydrophobicContact CB-CG 3.81Å; L280-G303 WeakPolarHBondContact O-CA 3.45Å; L280-G303 PolarHBondContact O-N 3.5Å; L280-Y333 HydrophobicContact CD1-CD2 4.38Å; L280-Y333 HydrophobicContact CD1-CE2 4.2Å; L280-I335 HydrophobicContact CD2-CB 3.99Å; L280-I335 HydrophobicContact CD2-CD1 4.09Å
281	H	90.9	Very high	92.4	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	16%	0.158	C	C	.	.			trans	-74.8	-45.5	177.3	-171.1	-49.4	0	0	0	111.9	L271 L274 D283 V284 C300 F302 G303 D338	L271-H281 HydrophobicContact CD2-CB 4.02Å; L274-H281 HydrophobicContact CD1-CB 4.25Å; H281-D283 PolarHBondContact CE1-O 3.05Å; H281-D283 VanDerWaalsContact CE1-O 3.32Å; H281-D283 PolarHBondContact ND1-N 3.18Å; H281-D283 PolarHBondContact O-N 2.76Å; H281-D283 VanDerWaalsContact O-N 3.17Å; H281-V284 HydrophobicContact CB-CG2 3.71Å; H281-C300 PolarHBondContact CE1-O 3.02Å; H281-C300 VanDerWaalsContact CE1-O 3.29Å; H281-C300 PolarHBondContact NE2-O 3.38Å; H281-F302 HydrophobicContact CB-CB 4.2Å; H281-G303 PolarHBondContact O-N 3.42Å; H281-D338 PolarHBondContact N-OD2 3.39Å
282	R	88.1	Confident	92.4	Very high	64 Å²	64	31.6 Å²	31.6	24%	0.242	16%	0.158	C	C	.	.	S	Bend	trans	66	3.6	176.9	-50.9	-178.3	178.4	-176.3	5	116.9	L280 Q307 R327 D338	L280-R282 HydrophobicContact CB-CG 3.81Å; R282-Q307 VanDerWaalsContact NH1-OE1 3.08Å; R282-R327 PolarHBondContact O-NH1 3.46Å; R282-R327 PolarHBondContact O-NH2 3.35Å; R282-D338 WeakPolarHBondContact CA-OD1 3.4Å; R282-D338 PolarHBondContact N-OD1 3.41Å
283	D	87.9	Confident	92.4	Very high	18 Å²	18	32.1 Å²	32.1	10%	0.096	16%	0.161	C	C	.	.			trans	-158.2	45.7	-179	-164.4	26.3	0	0	0	110.7	H281 K285 N288 T306 T319	H281-D283 PolarHBondContact CE1-O 3.05Å; H281-D283 VanDerWaalsContact CE1-O 3.32Å; H281-D283 PolarHBondContact ND1-N 3.18Å; H281-D283 PolarHBondContact O-N 2.76Å; H281-D283 VanDerWaalsContact O-N 3.17Å; D283-K285 PolarHBondContact O-N 3.22Å; D283-K285 WeakPolarHBondContact OD1-CE 3.49Å; D283-K285 IonicContact OD1-NZ 3.99Å; D283-K285 PolarHBondContact OD1-NZ 3.37Å; D283-K285 WeakPolarHBondContact OD2-CE 3.44Å; D283-K285 IonicContact OD2-NZ 3.61Å; D283-K285 PolarHBondContact OD2-NZ 3.35Å; D283-N288 PolarHBondContact O-ND2 2.91Å; D283-N288 PolarHBondContact OD2-ND2 2.53Å; D283-T306 HydrophobicContact CB-CG2 3.57Å; D283-T319 WeakPolarHBondContact OD1-CG2 3.45Å
284	V	94.5	Very high	92.5	Very high	1 Å²	1	36.7 Å²	36.7	1%	0.006	18%	0.178	C	C	.	.			trans	-71.3	116.5	177	-179.5	0	0	0	0	108.3	L271 H281 M289 D338 S341 L342	L271-V284 HydrophobicContact CD2-CG2 3.84Å; H281-V284 HydrophobicContact CB-CG2 3.71Å; V284-M289 HydrophobicContact CG1-CE 3.33Å; V284-D338 HydrophobicContact CG2-CB 3.98Å; V284-S341 WeakPolarHBondContact O-CB 3.17Å; V284-L342 HydrophobicContact CG1-CB 4.43Å
285	K	93.9	Very high	92.8	Very high	22 Å²	22	37 Å²	37	10%	0.096	18%	0.181	C	C	.	.	S	Bend	trans	-160	163	178.2	61.5	-174.1	177.5	-145.2	0	110	D283 S287 N288 M289 T319 Y322 S345	D283-K285 PolarHBondContact O-N 3.22Å; D283-K285 WeakPolarHBondContact OD1-CE 3.49Å; D283-K285 IonicContact OD1-NZ 3.99Å; D283-K285 PolarHBondContact OD1-NZ 3.37Å; D283-K285 WeakPolarHBondContact OD2-CE 3.44Å; D283-K285 IonicContact OD2-NZ 3.61Å; D283-K285 PolarHBondContact OD2-NZ 3.35Å; K285-S287 WeakPolarHBondContact CD-OG 3.42Å; K285-S287 WeakPolarHBondContact CE-OG 3.18Å; K285-S287 WeakPolarHBondContact CG-OG 3.33Å; K285-S287 PolarHBondContact O-N 2.94Å; K285-S287 VanDerWaalsContact O-N 3.15Å; K285-N288 WeakPolarHBondContact CE-ND2 3.47Å; K285-N288 HydrophobicContact CG-CB 4.18Å; K285-N288 PolarHBondContact O-N 2.99Å; K285-M289 PolarHBondContact O-N 3.45Å; K285-T319 VanDerWaalsContact NZ-CG2 3.27Å; K285-Y322 HydrophobicContact CB-CD1 4.01Å; K285-Y322 HydrophobicContact CB-CD2 3.75Å; K285-Y322 HydrophobicContact CB-CE1 4.14Å; K285-Y322 HydrophobicContact CB-CE2 3.88Å; K285-Y322 HydrophobicContact CB-CG 3.83Å; K285-Y322 HydrophobicContact CD-CD2 4.2Å; K285-Y322 HydrophobicContact CD-CE2 4.29Å; K285-S345 WeakPolarHBondContact CA-OG 3.32Å
286	P	95.6	Very high	93.1	Very high	1 Å²	1	36.9 Å²	36.9	1%	0.006	18%	0.183	C	C	.	.	G	3₁₀ helix	trans	-55.3	-34.5	-179.1	-28.8	38	0	0	0	114.1	L249 D250 N288 M289 Y322 L349	L249-P286 HydrophobicContact CB-CB 4.12Å; L249-P286 WeakPolarHBondContact CB-O 3.43Å; L249-P286 PolarHBondContact N-O 3.46Å; D250-P286 HydrophobicContact CB-CB 3.93Å; D250-P286 PolarHBondContact N-O 3.24Å; P286-N288 PolarHBondContact O-N 2.98Å; P286-M289 PolarHBondContact O-N 3.24Å; P286-Y322 HydrophobicContact CG-CE1 4.48Å; P286-L349 HydrophobicContact CB-CD1 4.47Å; P286-L349 HydrophobicContact CB-CD2 4.01Å; P286-L349 HydrophobicContact CB-CG 4.38Å; P286-L349 HydrophobicContact CG-CD1 4.34Å; P286-L349 HydrophobicContact CG-CD2 4.1Å; P286-L349 HydrophobicContact CG-CG 4.05Å
287	S	92	Very high	93.4	Very high	40 Å²	40	33.6 Å²	33.6	28%	0.28	16%	0.16	S	C	.	.	G	3₁₀ helix	trans	-69.7	-16.2	177.5	47.8	0	0	0	0	114.9	S248 D250 K285	S248-S287 WeakPolarHBondContact CB-O 3.46Å; D250-S287 WeakPolarHBondContact OD1-CA 3.39Å; K285-S287 WeakPolarHBondContact CD-OG 3.42Å; K285-S287 WeakPolarHBondContact CE-OG 3.18Å; K285-S287 WeakPolarHBondContact CG-OG 3.33Å; K285-S287 PolarHBondContact O-N 2.94Å; K285-S287 VanDerWaalsContact O-N 3.15Å
288	N	93.8	Very high	93.9	Very high	9 Å²	9	31 Å²	31	5%	0.048	15%	0.146	C	C	.	.	G	3₁₀ helix	trans	-105.3	9.5	175.9	-70.7	-10.8	0	0	0	113	D283 K285 P286 C300	D283-N288 PolarHBondContact O-ND2 2.91Å; D283-N288 PolarHBondContact OD2-ND2 2.53Å; K285-N288 WeakPolarHBondContact CE-ND2 3.47Å; K285-N288 HydrophobicContact CG-CB 4.18Å; K285-N288 PolarHBondContact O-N 2.99Å; P286-N288 PolarHBondContact O-N 2.98Å; N288-C300 PolarHBondContact O-N 3.36Å; N288-C300 PolarHBondContact O-SG 3.35Å
289	M	97.1	Very high	94.4	Very high	0 Å²	0	24.8 Å²	24.8	0%	0	12%	0.119	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-110.1	112.6	172.4	-63.1	171.6	-167.5	0	0	107.8	S248 L249 V267 V284 K285 P286 L299 F346	S248-M289 CarbonylContact C-O 3.5Å; S248-M289 VanDerWaalsContact CA-O 3.29Å; S248-M289 WeakPolarHBondContact CA-O 3.28Å; L249-M289 HydrophobicContact CB-CB 4.29Å; L249-M289 HydrophobicContact CD1-CB 3.59Å; L249-M289 HydrophobicContact CD1-CG 4.42Å; L249-M289 HydrophobicContact CD1-SD 4.01Å; L249-M289 HydrophobicContact CG-CB 3.86Å; L249-M289 WeakPolarHBondContact CG-O 3.47Å; L249-M289 PolarHBondContact N-O 2.82Å; V267-M289 HydrophobicContact CG1-CE 4.13Å; V267-M289 HydrophobicContact CG2-CE 4.46Å; V267-M289 HydrophobicContact CG2-CG 4.17Å; V267-M289 HydrophobicContact CG2-SD 3.92Å; V284-M289 HydrophobicContact CG1-CE 3.33Å; K285-M289 PolarHBondContact O-N 3.45Å; P286-M289 PolarHBondContact O-N 3.24Å; M289-L299 HydrophobicContact CG-CD2 3.82Å; M289-F346 HydrophobicContact CE-CE2 4.2Å; M289-F346 HydrophobicContact SD-CE2 4.14Å
290	L	97.6	Very high	94.7	Very high	30 Å²	30	24.1 Å²	24.1	16%	0.157	12%	0.117	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-101.8	144.4	-176.8	-59.8	-179.9	0	0	0	111.2	I225 M244 G247 V297 K298 C300	I225-L290 HydrophobicContact CD1-CD1 3.75Å; I225-L290 HydrophobicContact CG1-CD1 4.33Å; M244-L290 HydrophobicContact CB-CB 3.85Å; M244-L290 HydrophobicContact CB-CD1 4.34Å; M244-L290 HydrophobicContact CE-CB 4.34Å; M244-L290 HydrophobicContact CG-CB 3.76Å; M244-L290 HydrophobicContact CG-CD1 4.05Å; G247-L290 CarbonylContact O-C 3.51Å; G247-L290 WeakPolarHBondContact O-CA 3.49Å; L290-V297 CarbonylContact O-C 3.52Å; L290-V297 VanDerWaalsContact O-CA 3.29Å; L290-V297 WeakPolarHBondContact O-CA 3.49Å; L290-K298 PolarHBondContact N-O 2.52Å; L290-K298 PolarHBondContact O-N 2.9Å; L290-C300 HydrophobicContact CD1-CB 3.86Å; L290-C300 HydrophobicContact CG-CB 4.31Å
291	V	98.2	Very high	94.6	Very high	0 Å²	0	25.1 Å²	25.1	0%	0	12%	0.122	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-129.8	155.3	177	75.2	0	0	0	0	111.3	G246 G247 L249 Y252 Q296 V297 V430 V434	G246-V291 CarbonylContact C-O 3.59Å; G246-V291 VanDerWaalsContact C-O 3.31Å; G246-V291 WeakPolarHBondContact CA-O 3.33Å; G246-V291 PolarHBondContact N-O 2.98Å; G247-V291 PolarHBondContact N-O 3.36Å; G247-V291 PolarHBondContact O-N 3.28Å; L249-V291 HydrophobicContact CD2-CB 4.11Å; L249-V291 HydrophobicContact CD2-CG1 4Å; Y252-V291 HydrophobicContact CE2-CG1 3.95Å; V291-Q296 VanDerWaalsContact CA-O 3.31Å; V291-Q296 WeakPolarHBondContact CA-O 3.5Å; V291-Q296 WeakPolarHBondContact CG2-O 3.39Å; V291-V297 HydrophobicContact CG2-CG2 3.94Å; V291-V430 HydrophobicContact CG2-CG1 3.7Å; V291-V434 HydrophobicContact CB-CG2 4.33Å; V291-V434 HydrophobicContact CG1-CG1 4.36Å; V291-V434 HydrophobicContact CG1-CG2 3.73Å; V291-V434 HydrophobicContact CG2-CG2 3.63Å
292	N	97.8	Very high	94.1	Very high	0 Å²	0	25.3 Å²	25.3	0%	0	12%	0.123	C	C	.	.			trans	-130.4	166.9	174.6	69.3	25.2	0	0	0	112.2	M244 D245 R294 G295 Q296	M244-N292 HydrophobicContact CE-CB 3.96Å; M244-N292 HydrophobicContact SD-CB 4.13Å; D245-N292 WeakPolarHBondContact OD1-CA 3.18Å; D245-N292 WeakPolarHBondContact OD1-CB 3.46Å; N292-R294 PolarHBondContact ND2-NH2 3.24Å; N292-R294 VanDerWaalsContact ND2-NH2 3.12Å; N292-R294 PolarHBondContact O-N 3.03Å; N292-R294 VanDerWaalsContact O-N 3.09Å; N292-R294 WeakPolarHBondContact OD1-CA 3.41Å; N292-R294 WeakPolarHBondContact OD1-CB 3.16Å; N292-R294 PolarHBondContact OD1-N 3.24Å; N292-R294 VanDerWaalsContact OD1-N 3.12Å; N292-G295 PolarHBondContact O-N 3.47Å; N292-G295 PolarHBondContact OD1-N 3.27Å; N292-Q296 PolarHBondContact N-O 2.96Å; N292-Q296 VanDerWaalsContact N-O 3.16Å; N292-Q296 PolarHBondContact ND2-OE1 3.21Å; N292-Q296 WeakPolarHBondContact OD1-CB 3.48Å; N292-Q296 PolarHBondContact OD1-N 3.13Å
293	T	97.4	Very high	93.3	Very high	43 Å²	43	22.4 Å²	22.4	26%	0.264	11%	0.112	S	C	.	.	T	Hydrogen-bonded Turn	trans	-64.6	-11.5	-179.8	55.4	0	0	0	0	113.4	D245 G295 S431 V434 L438	D245-T293 PolarHBondContact OD1-N 3.37Å; D245-T293 PolarHBondContact OD1-OG1 2.98Å; D245-T293 WeakPolarHBondContact OD2-CB 3.3Å; D245-T293 VanDerWaalsContact OD2-CG2 3.28Å; D245-T293 WeakPolarHBondContact OD2-CG2 3.25Å; D245-T293 PolarHBondContact OD2-OG1 3.41Å; T293-G295 VanDerWaalsContact C-N 3.32Å; T293-S431 WeakPolarHBondContact O-CB 3.4Å; T293-S431 PolarHBondContact O-OG 2.74Å; T293-V434 HydrophobicContact CG2-CG1 4.46Å; T293-L438 HydrophobicContact CG2-CD1 3.88Å
294	R	97.5	Very high	92	Very high	145 Å²	145	22.4 Å²	22.4	55%	0.547	11%	0.113	S	C	.	.	T	Hydrogen-bonded Turn	trans	-86.6	-0.1	170.5	-57.1	-175.9	-63.8	-87.6	2	113.2	N292 Q296	N292-R294 PolarHBondContact ND2-NH2 3.24Å; N292-R294 VanDerWaalsContact ND2-NH2 3.12Å; N292-R294 PolarHBondContact O-N 3.03Å; N292-R294 VanDerWaalsContact O-N 3.09Å; N292-R294 WeakPolarHBondContact OD1-CA 3.41Å; N292-R294 WeakPolarHBondContact OD1-CB 3.16Å; N292-R294 PolarHBondContact OD1-N 3.24Å; N292-R294 VanDerWaalsContact OD1-N 3.12Å; R294-Q296 VanDerWaalsContact C-N 3.33Å; R294-Q296 HydrophobicContact CB-CG 4.4Å
295	G	97.5	Very high	90.3	Very high	7 Å²	7	22.6 Å²	22.6	7%	0.072	11%	0.114	C	C	.	.			trans	78.4	12.3	-179.5	0	0	0	0	0	114.6	N292 T293	N292-G295 PolarHBondContact O-N 3.47Å; N292-G295 PolarHBondContact OD1-N 3.27Å; T293-G295 VanDerWaalsContact C-N 3.32Å
296	Q	98.3	Very high	88.7	Confident	66 Å²	66	21.8 Å²	21.8	31%	0.308	11%	0.111	S	C	.	.			trans	-78.3	138	174.2	-54.1	175.5	-63.5	0	0	109.3	M244 V291 N292 R294	M244-Q296 HydrophobicContact CE-CB 4.41Å; M244-Q296 WeakPolarHBondContact CE-O 3.39Å; V291-Q296 VanDerWaalsContact CA-O 3.31Å; V291-Q296 WeakPolarHBondContact CA-O 3.5Å; V291-Q296 WeakPolarHBondContact CG2-O 3.39Å; N292-Q296 PolarHBondContact N-O 2.96Å; N292-Q296 VanDerWaalsContact N-O 3.16Å; N292-Q296 PolarHBondContact ND2-OE1 3.21Å; N292-Q296 WeakPolarHBondContact OD1-CB 3.48Å; N292-Q296 PolarHBondContact OD1-N 3.13Å; R294-Q296 VanDerWaalsContact C-N 3.33Å; R294-Q296 HydrophobicContact CB-CG 4.4Å
297	V	98.4	Very high	87.1	Confident	6 Å²	6	25.2 Å²	25.2	4%	0.036	13%	0.127	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-120.9	129.3	177.3	175.5	0	0	0	0	108.2	I263 A266 V267 L290 V291 V430	I263-V297 HydrophobicContact CB-CG2 4.43Å; I263-V297 HydrophobicContact CG1-CG2 4.01Å; I263-V297 HydrophobicContact CG2-CG1 3.91Å; I263-V297 HydrophobicContact CG2-CG2 4.31Å; A266-V297 HydrophobicContact CB-CB 3.59Å; A266-V297 HydrophobicContact CB-CG1 3.92Å; A266-V297 HydrophobicContact CB-CG2 4.38Å; V267-V297 HydrophobicContact CG2-CG1 4.12Å; L290-V297 CarbonylContact O-C 3.52Å; L290-V297 VanDerWaalsContact O-CA 3.29Å; L290-V297 WeakPolarHBondContact O-CA 3.49Å; V291-V297 HydrophobicContact CG2-CG2 3.94Å; V297-V430 HydrophobicContact CG2-CG1 4.19Å
298	K	97.9	Very high	85.5	Confident	19 Å²	19	23.5 Å²	23.5	8%	0.083	12%	0.115	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-138.6	139.8	-174.8	-62.6	-172.6	173.2	-160.1	0	112	S222 Y223 I224 I225 E242 M244 L290	S222-K298 VanDerWaalsContact O-CE 3.27Å; S222-K298 WeakPolarHBondContact O-CE 3.29Å; Y223-K298 WeakPolarHBondContact O-CA 3.15Å; I224-K298 WeakPolarHBondContact O-CD 3.46Å; I225-K298 HydrophobicContact CD1-CB 4.47Å; I225-K298 HydrophobicContact CD1-CD 4.45Å; E242-K298 WeakPolarHBondContact OE1-CD 3.38Å; E242-K298 WeakPolarHBondContact OE1-CE 3.42Å; E242-K298 IonicContact OE1-NZ 2.8Å; E242-K298 PolarHBondContact OE1-NZ 2.92Å; E242-K298 IonicContact OE2-NZ 3.13Å; E242-K298 PolarHBondContact OE2-NZ 3.47Å; M244-K298 HydrophobicContact CE-CB 4.16Å; M244-K298 HydrophobicContact CE-CD 4.12Å; M244-K298 HydrophobicContact CE-CG 3.97Å; M244-K298 HydrophobicContact SD-CD 4.14Å; L290-K298 PolarHBondContact N-O 2.52Å; L290-K298 PolarHBondContact O-N 2.9Å
299	L	96.3	Very high	83.8	Confident	1 Å²	1	23.8 Å²	23.8	1%	0.005	12%	0.117	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-80.6	139.3	171.1	-68.5	169.4	0	0	0	110.7	Y223 I224 I225 V267 L271 M289	Y223-L299 PolarHBondContact O-N 3.47Å; I224-L299 HydrophobicContact CD1-CB 4.09Å; I224-L299 HydrophobicContact CD1-CD1 4.46Å; I225-L299 WeakPolarHBondContact CB-O 3.34Å; I225-L299 PolarHBondContact N-O 3.42Å; V267-L299 HydrophobicContact CG1-CD1 4.32Å; V267-L299 HydrophobicContact CG1-CD2 4.12Å; L271-L299 HydrophobicContact CD2-CD1 3.9Å; L271-L299 HydrophobicContact CG-CD1 4.03Å; M289-L299 HydrophobicContact CG-CD2 3.82Å
300	C	91.8	Very high	81.9	Confident	11 Å²	11	27.6 Å²	27.6	7%	0.074	14%	0.138	C	C	.	.			trans	-130	174.8	174.1	69	0	0	0	0	111.1	I225 H281 N288 L290 F302	I225-C300 HydrophobicContact CB-CB 3.97Å; I225-C300 HydrophobicContact CG1-CB 4.4Å; I225-C300 HydrophobicContact CG2-CB 3.7Å; H281-C300 PolarHBondContact CE1-O 3.02Å; H281-C300 VanDerWaalsContact CE1-O 3.29Å; H281-C300 PolarHBondContact NE2-O 3.38Å; N288-C300 PolarHBondContact O-N 3.36Å; N288-C300 PolarHBondContact O-SG 3.35Å; L290-C300 HydrophobicContact CD1-CB 3.86Å; L290-C300 HydrophobicContact CG-CB 4.31Å; C300-F302 VanDerWaalsContact C-N 3.3Å; C300-F302 PolarHBondContact O-N 3.5Å
301	D	84.2	Confident	79.8	Confident	45 Å²	45	30 Å²	30	24%	0.241	16%	0.157	C	C	.	.	S	Bend	trans	52.1	45.6	173.9	-77.3	-26.6	0	0	0	113.5	K195 S305 T306	K195-D301 IonicContact NZ-OD1 3.69Å; K195-D301 PolarHBondContact NZ-OD1 3.27Å; K195-D301 IonicContact NZ-OD2 3.59Å; K195-D301 PolarHBondContact NZ-OD2 3.46Å; D301-S305 WeakPolarHBondContact CA-OG 3.45Å; D301-T306 PolarHBondContact O-OG1 3.41Å
302	F	81.1	Confident	77.5	Confident	4 Å²	4	32.2 Å²	32.2	2%	0.018	17%	0.168	C	C	.	.			trans	-101.9	150.7	-177.3	61.5	-90.6	0	0	0	113.6	L216 C219 I224 L274 I279 H281 C300 V304 S305	L216-F302 HydrophobicContact CD2-CD1 4.36Å; L216-F302 HydrophobicContact CD2-CD2 4.02Å; L216-F302 HydrophobicContact CD2-CE1 3.73Å; L216-F302 HydrophobicContact CD2-CE2 3.36Å; L216-F302 HydrophobicContact CD2-CG 4.49Å; L216-F302 HydrophobicContact CD2-CZ 3.19Å; C219-F302 HydrophobicContact CB-CZ 4.36Å; I224-F302 HydrophobicContact CG2-CD1 4.27Å; I224-F302 HydrophobicContact CG2-CE1 3.29Å; I224-F302 HydrophobicContact CG2-CZ 3.51Å; L274-F302 HydrophobicContact CD1-CB 4.09Å; L274-F302 HydrophobicContact CD1-CD2 4.04Å; L274-F302 HydrophobicContact CD1-CG 4.01Å; L274-F302 HydrophobicContact CD2-CD2 3.64Å; L274-F302 HydrophobicContact CD2-CE2 3.48Å; L274-F302 VanDerWaalsContact CD2-CE2 3.48Å; L274-F302 HydrophobicContact CD2-CG 4.29Å; L274-F302 HydrophobicContact CD2-CZ 4.02Å; I279-F302 HydrophobicContact CG2-CD2 4.06Å; I279-F302 HydrophobicContact CG2-CE2 4.47Å; H281-F302 HydrophobicContact CB-CB 4.2Å; C300-F302 VanDerWaalsContact C-N 3.3Å; C300-F302 PolarHBondContact O-N 3.5Å; F302-V304 PolarHBondContact O-N 3.47Å; F302-S305 PolarHBondContact N-OG 3.04Å; F302-S305 PolarHBondContact O-N 3.04Å; F302-S305 PolarHBondContact O-OG 3Å; F302-S305 VanDerWaalsContact O-OG 3.12Å
303	G	70.9	Confident	75.1	Confident	2 Å²	2	33.3 Å²	33.3	2%	0.021	18%	0.177	C	C	.	.	T	Hydrogen-bonded Turn	trans	60.6	-92.7	168.4	0	0	0	0	0	113	L280 H281 T306 Q307	L280-G303 WeakPolarHBondContact O-CA 3.45Å; L280-G303 PolarHBondContact O-N 3.5Å; H281-G303 PolarHBondContact O-N 3.42Å; G303-T306 PolarHBondContact N-OG1 3.38Å; G303-Q307 WeakPolarHBondContact O-CG 3.35Å; G303-Q307 PolarHBondContact O-N 3.05Å; G303-Q307 PolarHBondContact O-NE2 3.17Å
304	V	59.3	Low	72.3	Confident	18 Å²	18	40.5 Å²	40.5	11%	0.109	21%	0.205	C	C	.	.	H	α-helix	trans	-89.3	-38.7	-165.7	-174.7	0	0	0	0	112.2	E212 I215 F302 T306 Q307 L308	E212-V304 HydrophobicContact CB-CB 4.46Å; E212-V304 HydrophobicContact CB-CG1 3.08Å; E212-V304 VanDerWaalsContact CD-CG1 3.45Å; E212-V304 HydrophobicContact CG-CG1 3.22Å; E212-V304 WeakPolarHBondContact OE2-CG1 3.13Å; I215-V304 HydrophobicContact CD1-CG2 3.78Å; F302-V304 PolarHBondContact O-N 3.47Å; V304-T306 PolarHBondContact O-N 3.29Å; V304-Q307 PolarHBondContact O-N 3.23Å; V304-L308 WeakPolarHBondContact O-CB 3.49Å; V304-L308 PolarHBondContact O-N 2.62Å
305	S	60.7	Low	69.5	Low	5 Å²	5	38.1 Å²	38.1	4%	0.035	21%	0.206	C	C	.	.	H	α-helix	trans	-61.1	-32.6	170.9	54.4	0	0	0	0	111.7	D301 F302 V309	D301-S305 WeakPolarHBondContact CA-OG 3.45Å; F302-S305 PolarHBondContact N-OG 3.04Å; F302-S305 PolarHBondContact O-N 3.04Å; F302-S305 PolarHBondContact O-OG 3Å; F302-S305 VanDerWaalsContact O-OG 3.12Å; S305-V309 VanDerWaalsContact O-CG2 3.3Å; S305-V309 WeakPolarHBondContact O-CG2 3.49Å; S305-V309 PolarHBondContact O-N 3.15Å; S305-V309 VanDerWaalsContact O-N 3.08Å
306	T	60.3	Low	66.9	Low	6 Å²	6	47.5 Å²	47.5	4%	0.037	24%	0.241	C	C	.	.	H	α-helix	trans	-70.8	-45.5	175.1	-31.5	0	0	0	0	111.6	D283 D301 G303 V304 L308 V309 N310	D283-T306 HydrophobicContact CB-CG2 3.57Å; D301-T306 PolarHBondContact O-OG1 3.41Å; G303-T306 PolarHBondContact N-OG1 3.38Å; V304-T306 PolarHBondContact O-N 3.29Å; T306-L308 VanDerWaalsContact C-N 3.26Å; T306-L308 PolarHBondContact O-N 2.9Å; T306-V309 PolarHBondContact O-N 3.31Å; T306-N310 WeakPolarHBondContact O-CB 3.38Å; T306-N310 PolarHBondContact O-N 3.49Å; T306-N310 PolarHBondContact O-ND2 2.72Å
307	Q	60.6	Low	64.2	Low	73 Å²	73	48.9 Å²	48.9	34%	0.341	25%	0.254	S	S	.	.	H	α-helix	trans	-61.4	-39.3	176.4	-81.4	167.5	87.9	0	0	111.3	R282 G303 V304 N310 S311	R282-Q307 VanDerWaalsContact NH1-OE1 3.08Å; G303-Q307 WeakPolarHBondContact O-CG 3.35Å; G303-Q307 PolarHBondContact O-N 3.05Å; G303-Q307 PolarHBondContact O-NE2 3.17Å; V304-Q307 PolarHBondContact O-N 3.23Å; Q307-N310 PolarHBondContact O-N 3.05Å; Q307-S311 WeakPolarHBondContact O-CB 3.49Å; Q307-S311 PolarHBondContact O-N 2.92Å; Q307-S311 PolarHBondContact O-OG 3.08Å
308	L	59.2	Low	61.6	Low	3 Å²	3	51.4 Å²	51.4	2%	0.016	28%	0.281	C	S	.	.	H	α-helix	trans	-59.9	-52.5	173.9	-176.2	63.1	0	0	0	111.4	I209 V304 T306 N310 S311 I312	I209-L308 HydrophobicContact CB-CD1 4.47Å; I209-L308 HydrophobicContact CD1-CD1 3.68Å; I209-L308 HydrophobicContact CD1-CD2 4.37Å; I209-L308 HydrophobicContact CG1-CD1 3.34Å; I209-L308 HydrophobicContact CG1-CD2 4.11Å; I209-L308 HydrophobicContact CG1-CG 4.36Å; I209-L308 HydrophobicContact CG2-CD2 3.74Å; V304-L308 WeakPolarHBondContact O-CB 3.49Å; V304-L308 PolarHBondContact O-N 2.62Å; T306-L308 VanDerWaalsContact C-N 3.26Å; T306-L308 PolarHBondContact O-N 2.9Å; L308-N310 VanDerWaalsContact C-N 3.28Å; L308-N310 PolarHBondContact O-N 3.18Å; L308-S311 PolarHBondContact O-N 2.83Å; L308-S311 PolarHBondContact O-OG 3.39Å; L308-I312 HydrophobicContact CD1-CD1 3.34Å; L308-I312 HydrophobicContact CG-CD1 3.77Å; L308-I312 WeakPolarHBondContact O-CB 3.47Å; L308-I312 WeakPolarHBondContact O-CD1 3.14Å; L308-I312 PolarHBondContact O-N 3.03Å
309	V	57.6	Low	59.7	Low	15 Å²	15	52.2 Å²	52.2	9%	0.091	29%	0.288	C	S	.	.	H	α-helix	trans	-58.3	-42.7	176.9	168.2	0	0	0	0	111.2	I197 S305 T306 I312 A313	I197-V309 HydrophobicContact CD1-CG2 3.91Å; S305-V309 VanDerWaalsContact O-CG2 3.3Å; S305-V309 WeakPolarHBondContact O-CG2 3.49Å; S305-V309 PolarHBondContact O-N 3.15Å; S305-V309 VanDerWaalsContact O-N 3.08Å; T306-V309 PolarHBondContact O-N 3.31Å; V309-I312 PolarHBondContact O-N 3.38Å; V309-A313 WeakPolarHBondContact O-CB 3.38Å; V309-A313 PolarHBondContact O-N 3.01Å
310	N	56.8	Low	58.4	Low	81 Å²	81	53.8 Å²	53.8	43%	0.433	30%	0.296	S	S	.	.	H	α-helix	trans	-73.3	-35.2	-176.6	-70.1	-18.6	0	0	0	113.7	T306 Q307 L308 I312	T306-N310 WeakPolarHBondContact O-CB 3.38Å; T306-N310 PolarHBondContact O-N 3.49Å; T306-N310 PolarHBondContact O-ND2 2.72Å; Q307-N310 PolarHBondContact O-N 3.05Å; L308-N310 VanDerWaalsContact C-N 3.28Å; L308-N310 PolarHBondContact O-N 3.18Å; N310-I312 PolarHBondContact O-N 3.18Å
311	S	54.3	Low	58	Low	80 Å²	80	54 Å²	54	56%	0.559	30%	0.298	S	S	*	.	H	α-helix	trans	-66.7	-28.1	176.6	64.7	0	0	0	0	111.7	Q307 L308	Q307-S311 WeakPolarHBondContact O-CB 3.49Å; Q307-S311 PolarHBondContact O-N 2.92Å; Q307-S311 PolarHBondContact O-OG 3.08Å; L308-S311 PolarHBondContact O-N 2.83Å; L308-S311 PolarHBondContact O-OG 3.39Å
312	I	50.4	Low	58.4	Low	46 Å²	46	53.4 Å²	53.4	24%	0.236	29%	0.293	C	S	.	.	H	α-helix	trans	-94	-41.1	-177.1	-74.8	137.6	0	0	0	112.7	L199 L308 V309 N310 K314	L199-I312 HydrophobicContact CD1-CD1 4.14Å; L199-I312 HydrophobicContact CD2-CB 3.84Å; L199-I312 HydrophobicContact CD2-CD1 3.11Å; L199-I312 HydrophobicContact CD2-CG1 3.41Å; L199-I312 VanDerWaalsContact CD2-CG1 3.41Å; L199-I312 HydrophobicContact CD2-CG2 3.29Å; L199-I312 HydrophobicContact CG-CD1 4.27Å; L308-I312 HydrophobicContact CD1-CD1 3.34Å; L308-I312 HydrophobicContact CG-CD1 3.77Å; L308-I312 WeakPolarHBondContact O-CB 3.47Å; L308-I312 WeakPolarHBondContact O-CD1 3.14Å; L308-I312 PolarHBondContact O-N 3.03Å; V309-I312 PolarHBondContact O-N 3.38Å; N310-I312 PolarHBondContact O-N 3.18Å; I312-K314 PolarHBondContact O-N 3.26Å
313	A	46.3	Very low	58.8	Low	24 Å²	24	54.2 Å²	54.2	20%	0.198	30%	0.297	C	S	.	.	H	α-helix	trans	-67.5	-13.4	-166.6	0	0	0	0	0	114	V309 T315	V309-A313 WeakPolarHBondContact O-CB 3.38Å; V309-A313 PolarHBondContact O-N 3.01Å; A313-T315 WeakPolarHBondContact O-CB 3.33Å; A313-T315 PolarHBondContact O-N 3.21Å; A313-T315 PolarHBondContact O-OG1 3.38Å
314	K	39.8	Very low	59.8	Low	193 Å²	193	54.1 Å²	54.1	84%	0.839	30%	0.297	S	S	*	.			trans	46.6	5.2	179.2	-68.9	-172.3	-179.2	-177.7	0	116.3	I312	I312-K314 PolarHBondContact O-N 3.26Å
315	T	38.7	Very low	61.4	Low	95 Å²	95	53.8 Å²	53.8	58%	0.583	29%	0.294	S	S	*	.			trans	-119.6	102.7	-172	32.9	0	0	0	0	109.1	A313 V317	A313-T315 WeakPolarHBondContact O-CB 3.33Å; A313-T315 PolarHBondContact O-N 3.21Å; A313-T315 PolarHBondContact O-OG1 3.38Å; T315-V317 PolarHBondContact O-N 3.37Å; T315-V317 VanDerWaalsContact O-N 3.13Å
316	Y	42.8	Very low	62.8	Low	205 Å²	205	53.8 Å²	53.8	80%	0.804	29%	0.294	S	S	*	.			trans	-72.5	7.4	-176.9	-107.5	-98.7	0	0	0	114.7	N320	Y316-N320 PolarHBondContact O-ND2 2.77Å
317	V	40	Very low	64.1	Low	95 Å²	95	56.1 Å²	56.1	58%	0.576	30%	0.302	S	S	*	.	S	Bend	trans	-116.5	107.7	-161.8	-174.2	0	0	0	0	110.7	T315 P368	T315-V317 PolarHBondContact O-N 3.37Å; T315-V317 VanDerWaalsContact O-N 3.13Å; V317-P368 HydrophobicContact CG1-CB 4.26Å; V317-P368 HydrophobicContact CG1-CG 3.64Å
318	G	45.2	Very low	65.3	Low	59 Å²	59	54.8 Å²	54.8	61%	0.608	30%	0.297	S	S	*	.	S	Bend	trans	138.9	-38.8	166.8	0	0	0	0	0	115.6
319	T	56.8	Low	66.3	Low	36 Å²	36	57.8 Å²	57.8	22%	0.221	32%	0.318	C	S	.	.	G	3₁₀ helix	trans	-85.7	-13.2	-171.6	-57.5	0	0	0	0	114.5	D283 K285 A321	D283-T319 WeakPolarHBondContact OD1-CG2 3.45Å; K285-T319 VanDerWaalsContact NZ-CG2 3.27Å; T319-A321 VanDerWaalsContact C-N 3.3Å; T319-A321 PolarHBondContact O-N 3.23Å
320	N	70	Confident	67.2	Low	33 Å²	33	60.4 Å²	60.4	18%	0.176	35%	0.348	C	S	.	.	G	3₁₀ helix	trans	-80.4	-5.1	-167.7	-59.6	-17.6	0	0	0	114.4	Y316 Y322 M323 L372	Y316-N320 PolarHBondContact O-ND2 2.77Å; N320-Y322 PolarHBondContact O-N 3.24Å; N320-M323 HydrophobicContact CB-CE 3.94Å; N320-M323 WeakPolarHBondContact O-CB 3.45Å; N320-M323 PolarHBondContact O-N 3.07Å; N320-M323 WeakPolarHBondContact OD1-CE 3.36Å; N320-L372 HydrophobicContact CB-CD1 4.15Å; N320-L372 HydrophobicContact CB-CD2 3.53Å; N320-L372 HydrophobicContact CB-CG 4.42Å; N320-L372 WeakPolarHBondContact O-CD2 3.44Å
321	A	84.1	Confident	68.2	Low	15 Å²	15	61.9 Å²	61.9	12%	0.124	35%	0.352	C	S	.	.	G	3₁₀ helix	trans	-63.8	-26.7	-176.8	0	0	0	0	0	113.8	T319 F354 L371 I375	T319-A321 VanDerWaalsContact C-N 3.3Å; T319-A321 PolarHBondContact O-N 3.23Å; A321-F354 HydrophobicContact CB-CE1 4.3Å; A321-F354 HydrophobicContact CB-CE2 4.07Å; A321-F354 HydrophobicContact CB-CZ 3.64Å; A321-F354 WeakPolarHBondContact O-CZ 3.46Å; A321-L371 HydrophobicContact CB-CD2 3.73Å; A321-I375 VanDerWaalsContact O-CD1 3.32Å; A321-I375 WeakPolarHBondContact O-CD1 3.34Å
322	Y	91.3	Very high	69.2	Low	33 Å²	33	66.3 Å²	66.3	13%	0.129	36%	0.364	C	S	.	.	G	3₁₀ helix	trans	-91.7	-0.7	176.1	-56.9	-90.9	0	0	0	112.7	K285 P286 N320 S341 I344 E348 F354	K285-Y322 HydrophobicContact CB-CD1 4.01Å; K285-Y322 HydrophobicContact CB-CD2 3.75Å; K285-Y322 HydrophobicContact CB-CE1 4.14Å; K285-Y322 HydrophobicContact CB-CE2 3.88Å; K285-Y322 HydrophobicContact CB-CG 3.83Å; K285-Y322 HydrophobicContact CD-CD2 4.2Å; K285-Y322 HydrophobicContact CD-CE2 4.29Å; P286-Y322 HydrophobicContact CG-CE1 4.48Å; N320-Y322 PolarHBondContact O-N 3.24Å; Y322-S341 WeakPolarHBondContact O-CA 3.38Å; Y322-S341 WeakPolarHBondContact O-CB 3.45Å; Y322-S341 PolarHBondContact O-OG 2.96Å; Y322-I344 HydrophobicContact CD1-CB 4.2Å; Y322-I344 HydrophobicContact CD1-CG2 3.55Å; Y322-I344 HydrophobicContact CE1-CG2 3.93Å; Y322-I344 HydrophobicContact CG-CG2 4.46Å; Y322-E348 WeakPolarHBondContact CE1-OE2 3.25Å; Y322-E348 VanDerWaalsContact CZ-OE2 3.23Å; Y322-E348 PolarHBondContact OH-OE1 3.14Å; Y322-E348 PolarHBondContact OH-OE2 2.79Å; Y322-F354 HydrophobicContact CD1-CE2 4.31Å; Y322-F354 HydrophobicContact CE1-CD2 4.35Å; Y322-F354 AromaticContact CE1-CE2 3.87Å; Y322-F354 HydrophobicContact CE1-CE2 3.87Å; Y322-F354 HydrophobicContact CE2-CE2 4.4Å; Y322-F354 AromaticContact CZ-CE2 3.92Å
323	M	89.8	Confident	70.6	Confident	21 Å²	21	68.4 Å²	68.4	10%	0.103	37%	0.37	C	S	.	.			trans	-70.1	139.3	-174.9	-165.7	176.2	-66.9	0	0	110.6	N320 R327 I328 W340	N320-M323 HydrophobicContact CB-CE 3.94Å; N320-M323 WeakPolarHBondContact O-CB 3.45Å; N320-M323 PolarHBondContact O-N 3.07Å; N320-M323 WeakPolarHBondContact OD1-CE 3.36Å; M323-R327 HydrophobicContact CG-CB 3.73Å; M323-R327 HydrophobicContact CG-CG 3.71Å; M323-R327 HydrophobicContact SD-CB 4.09Å; M323-R327 HydrophobicContact SD-CG 3.63Å; M323-I328 HydrophobicContact CB-CD1 4.24Å; M323-I328 HydrophobicContact CB-CG1 3.91Å; M323-I328 HydrophobicContact CG-CG1 3.81Å; M323-I328 HydrophobicContact SD-CG1 3.74Å; M323-W340 PolarHBondContact O-NE1 3.13Å
324	A	92.4	Very high	72.5	Confident	1 Å²	1	68.3 Å²	68.3	1%	0.008	37%	0.372	C	S	.	.			trans	-70	149	176.8	0	0	0	0	0	111.7	E326 R327 I328 W340	A324-E326 VanDerWaalsContact C-N 3.32Å; A324-E326 VanDerWaalsContact CB-CD 3.4Å; A324-E326 VanDerWaalsContact CB-OE1 3.25Å; A324-E326 WeakPolarHBondContact CB-OE1 3.35Å; A324-E326 WeakPolarHBondContact CB-OE2 3.23Å; A324-E326 PolarHBondContact O-N 3.13Å; A324-R327 WeakPolarHBondContact O-CB 3.3Å; A324-R327 PolarHBondContact O-N 3.04Å; A324-I328 PolarHBondContact O-N 3.36Å; A324-I328 VanDerWaalsContact O-N 3.1Å; A324-W340 VanDerWaalsContact CA-CD1 3.41Å; A324-W340 HydrophobicContact CB-CB 3.68Å; A324-W340 HydrophobicContact CB-CD2 4.39Å; A324-W340 HydrophobicContact CB-CG 3.69Å
325	P	92.8	Very high	75	Confident	10 Å²	10	59.4 Å²	59.4	7%	0.065	33%	0.333	C	S	.	.	H	α-helix	trans	-54.3	-44.8	-175.8	-24.5	32	0	0	0	113.2	R327 I328 S329 W340 I375 K402	P325-R327 PolarHBondContact O-N 3.27Å; P325-I328 WeakPolarHBondContact O-CB 3.4Å; P325-I328 PolarHBondContact O-N 3.46Å; P325-I328 VanDerWaalsContact O-N 3.11Å; P325-S329 PolarHBondContact O-N 3.47Å; P325-S329 PolarHBondContact O-OG 2.97Å; P325-W340 HydrophobicContact CG-CD2 4.38Å; P325-W340 HydrophobicContact CG-CE3 4.16Å; P325-W340 HydrophobicContact CG-CH2 3.67Å; P325-W340 HydrophobicContact CG-CZ2 3.9Å; P325-W340 HydrophobicContact CG-CZ3 3.79Å; P325-I375 HydrophobicContact CG-CG2 4.2Å; P325-I375 WeakPolarHBondContact CG-O 3.32Å; P325-K402 HydrophobicContact CB-CD 4.45Å; P325-K402 HydrophobicContact CG-CD 3.76Å
326	E	90.7	Very high	77.6	Confident	6 Å²	6	57.6 Å²	57.6	3%	0.028	32%	0.318	C	S	.	.	H	α-helix	trans	-61	-32.6	179	73.3	-79.6	-164.1	0	0	112.2	A324 G330 E331 S337 P404 R407	A324-E326 VanDerWaalsContact C-N 3.32Å; A324-E326 VanDerWaalsContact CB-CD 3.4Å; A324-E326 VanDerWaalsContact CB-OE1 3.25Å; A324-E326 WeakPolarHBondContact CB-OE1 3.35Å; A324-E326 WeakPolarHBondContact CB-OE2 3.23Å; A324-E326 PolarHBondContact O-N 3.13Å; E326-G330 PolarHBondContact O-N 2.88Å; E326-E331 HydrophobicContact CB-CB 4.11Å; E326-E331 WeakPolarHBondContact O-CA 3.19Å; E326-E331 WeakPolarHBondContact O-CB 3.36Å; E326-E331 PolarHBondContact O-N 3.12Å; E326-S337 WeakPolarHBondContact OE1-CA 3.42Å; E326-S337 WeakPolarHBondContact OE1-CB 3.49Å; E326-S337 PolarHBondContact OE1-OG 3.45Å; E326-P404 HydrophobicContact CB-CG 3.73Å; E326-P404 HydrophobicContact CG-CB 4.46Å; E326-P404 HydrophobicContact CG-CG 3.61Å; E326-R407 IonicContact OE1-CZ 2.83Å; E326-R407 IonicContact OE1-NH1 3.58Å; E326-R407 PolarHBondContact OE1-NH1 3.43Å; E326-R407 IonicContact OE1-NH2 2.83Å; E326-R407 PolarHBondContact OE1-NH2 3.34Å; E326-R407 VanDerWaalsContact OE1-NH2 3.14Å; E326-R407 IonicContact OE2-CZ 2.72Å; E326-R407 IonicContact OE2-NH1 3.54Å; E326-R407 IonicContact OE2-NH2 2.74Å; E326-R407 PolarHBondContact OE2-NH2 3.19Å
327	R	87.3	Confident	80.1	Confident	55 Å²	55	48 Å²	48	21%	0.208	28%	0.281	C	S	.	.	H	α-helix	trans	-78.9	-32	178.9	-175.4	178.9	160.1	-162	3.2	111.3	R282 M323 A324 P325 G330 Y333	R282-R327 PolarHBondContact O-NH1 3.46Å; R282-R327 PolarHBondContact O-NH2 3.35Å; M323-R327 HydrophobicContact CG-CB 3.73Å; M323-R327 HydrophobicContact CG-CG 3.71Å; M323-R327 HydrophobicContact SD-CB 4.09Å; M323-R327 HydrophobicContact SD-CG 3.63Å; A324-R327 WeakPolarHBondContact O-CB 3.3Å; A324-R327 PolarHBondContact O-N 3.04Å; P325-R327 PolarHBondContact O-N 3.27Å; R327-G330 PolarHBondContact O-N 3.31Å; R327-Y333 HydrophobicContact CB-CG 4.4Å; R327-Y333 HydrophobicContact CG-CD1 4.13Å; R327-Y333 HydrophobicContact CG-CG 4.23Å
328	I	84.3	Confident	82.7	Confident	45 Å²	45	43.7 Å²	43.7	23%	0.231	25%	0.254	C	S	.	.	H	α-helix	trans	-66.2	-43.1	172.4	-63.9	170.3	0	0	0	110	M323 A324 P325 G330 L372 I375 V376	M323-I328 HydrophobicContact CB-CD1 4.24Å; M323-I328 HydrophobicContact CB-CG1 3.91Å; M323-I328 HydrophobicContact CG-CG1 3.81Å; M323-I328 HydrophobicContact SD-CG1 3.74Å; A324-I328 PolarHBondContact O-N 3.36Å; A324-I328 VanDerWaalsContact O-N 3.1Å; P325-I328 WeakPolarHBondContact O-CB 3.4Å; P325-I328 PolarHBondContact O-N 3.46Å; P325-I328 VanDerWaalsContact O-N 3.11Å; I328-G330 PolarHBondContact O-N 3.42Å; I328-L372 HydrophobicContact CD1-CB 4.27Å; I328-L372 HydrophobicContact CD1-CD2 3.7Å; I328-L372 HydrophobicContact CG1-CD2 4.12Å; I328-L372 HydrophobicContact CG2-CB 3.93Å; I328-I375 HydrophobicContact CD1-CB 3.84Å; I328-I375 HydrophobicContact CD1-CD1 4.31Å; I328-I375 HydrophobicContact CD1-CG2 3.49Å; I328-I375 VanDerWaalsContact CD1-CG2 3.49Å; I328-V376 HydrophobicContact CB-CG2 3.84Å; I328-V376 HydrophobicContact CD1-CG2 4.34Å; I328-V376 HydrophobicContact CG2-CG2 3.59Å
329	S	80.6	Confident	85.2	Confident	65 Å²	65	40.9 Å²	40.9	46%	0.455	23%	0.225	S	C	.	.	T	Hydrogen-bonded Turn	trans	-74.9	0.3	178.7	-56.9	0	0	0	0	114.4	P325 E331	P325-S329 PolarHBondContact O-N 3.47Å; P325-S329 PolarHBondContact O-OG 2.97Å; S329-E331 VanDerWaalsContact C-N 3.26Å; S329-E331 PolarHBondContact O-N 3.19Å
330	G	77.5	Confident	87.1	Confident	70 Å²	70	39.1 Å²	39.1	72%	0.722	22%	0.215	S	C	*	.	T	Hydrogen-bonded Turn	trans	72.5	14.8	-179.8	0	0	0	0	0	114.7	E326 R327 I328	E326-G330 PolarHBondContact O-N 2.88Å; R327-G330 PolarHBondContact O-N 3.31Å; I328-G330 PolarHBondContact O-N 3.42Å
331	E	78	Confident	88.4	Confident	113 Å²	113	37.8 Å²	37.8	53%	0.528	21%	0.208	S	C	.	.			trans	-74.7	170.3	177	-58.8	-176.7	179	0	0	112	E326 S329 Y333	E326-E331 HydrophobicContact CB-CB 4.11Å; E326-E331 WeakPolarHBondContact O-CA 3.19Å; E326-E331 WeakPolarHBondContact O-CB 3.36Å; E326-E331 PolarHBondContact O-N 3.12Å; S329-E331 VanDerWaalsContact C-N 3.26Å; S329-E331 PolarHBondContact O-N 3.19Å; E331-Y333 PolarHBondContact O-N 2.88Å; E331-Y333 VanDerWaalsContact O-N 3.1Å
332	Q	74.9	Confident	89.1	Confident	173 Å²	173	37 Å²	37	81%	0.808	20%	0.202	S	C	*	.			trans	-66.8	114	175.8	-174.8	161.8	48	0	0	110.6
333	Y	79.4	Confident	89.4	Confident	89 Å²	89	35.5 Å²	35.5	35%	0.349	20%	0.196	S	C	.	.			trans	-105.7	161	-179.3	71.8	-93.2	0	0	0	111.5	L280 R327 E331 S337	L280-Y333 HydrophobicContact CD1-CD2 4.38Å; L280-Y333 HydrophobicContact CD1-CE2 4.2Å; R327-Y333 HydrophobicContact CB-CG 4.4Å; R327-Y333 HydrophobicContact CG-CD1 4.13Å; R327-Y333 HydrophobicContact CG-CG 4.23Å; E331-Y333 PolarHBondContact O-N 2.88Å; E331-Y333 VanDerWaalsContact O-N 3.1Å; Y333-S337 WeakPolarHBondContact CB-OG 3.47Å
334	G	86.5	Confident	89.7	Confident	23 Å²	23	34.5 Å²	34.5	24%	0.237	19%	0.191	C	C	.	.			trans	-159.6	-154.5	-175.2	0	0	0	0	0	111.7	H336 S337	G334-H336 PolarHBondContact O-N 3.37Å; G334-S337 PolarHBondContact N-OG 2.83Å; G334-S337 VanDerWaalsContact O-CB 3.3Å; G334-S337 WeakPolarHBondContact O-CB 3.24Å; G334-S337 PolarHBondContact O-N 3.22Å; G334-S337 PolarHBondContact O-OG 3.33Å
335	I	91.1	Very high	89.9	Confident	6 Å²	6	34.4 Å²	34.4	3%	0.031	19%	0.19	C	C	.	.	H	α-helix	trans	-60.7	-31.3	-177.1	-168.7	60.4	0	0	0	113.2	W275 L280 S337 D338 V339 P410	W275-I335 HydrophobicContact CB-CD1 3.9Å; W275-I335 HydrophobicContact CB-CG1 4.14Å; W275-I335 HydrophobicContact CD2-CB 3.85Å; W275-I335 HydrophobicContact CD2-CD1 4.19Å; W275-I335 HydrophobicContact CD2-CG1 3.88Å; W275-I335 HydrophobicContact CD2-CG2 4.2Å; W275-I335 HydrophobicContact CE3-CB 3.86Å; W275-I335 HydrophobicContact CE3-CD1 4.14Å; W275-I335 HydrophobicContact CE3-CG1 4.14Å; W275-I335 HydrophobicContact CG-CB 4.36Å; W275-I335 HydrophobicContact CG-CD1 4.1Å; W275-I335 HydrophobicContact CG-CG1 3.86Å; W275-I335 HydrophobicContact CH2-CB 4.35Å; W275-I335 HydrophobicContact CH2-CG2 4.38Å; W275-I335 HydrophobicContact CZ2-CB 4.34Å; W275-I335 HydrophobicContact CZ2-CG2 4.01Å; W275-I335 HydrophobicContact CZ3-CB 4.12Å; L280-I335 HydrophobicContact CD2-CB 3.99Å; L280-I335 HydrophobicContact CD2-CD1 4.09Å; I335-S337 PolarHBondContact O-N 3.31Å; I335-D338 HydrophobicContact CD1-CB 4.43Å; I335-D338 WeakPolarHBondContact O-CB 3.41Å; I335-D338 PolarHBondContact O-N 2.77Å; I335-V339 PolarHBondContact O-N 3.09Å; I335-P410 HydrophobicContact CD1-CG 3.88Å; I335-P410 HydrophobicContact CG1-CG 3.47Å; I335-P410 VanDerWaalsContact CG1-CG 3.47Å
336	H	94.7	Very high	90.2	Very high	56 Å²	56	34 Å²	34	26%	0.259	19%	0.187	S	C	.	.	H	α-helix	trans	-59.2	-29.3	175.9	-56	100.7	0	0	0	112.4	G334 D338 V339 W340 P404 R407	G334-H336 PolarHBondContact O-N 3.37Å; H336-D338 VanDerWaalsContact C-N 3.33Å; H336-D338 PolarHBondContact O-N 3.17Å; H336-V339 WeakPolarHBondContact O-CB 3.45Å; H336-V339 PolarHBondContact O-N 3.05Å; H336-V339 VanDerWaalsContact O-N 3.15Å; H336-W340 PolarHBondContact O-N 3.1Å; H336-P404 HydrophobicContact CB-CB 4.22Å; H336-P404 WeakPolarHBondContact CB-O 3.3Å; H336-P404 PolarHBondContact CD2-O 3.1Å; H336-R407 HydrophobicContact CB-CB 4.25Å; H336-R407 PolarHBondContact CD2-O 3.39Å; H336-R407 WeakPolarHBondContact O-CD 3.37Å; H336-R407 PolarHBondContact O-NH1 3.39Å
337	S	93.9	Very high	90.5	Very high	4 Å²	4	33.9 Å²	33.9	3%	0.028	19%	0.187	C	C	.	.	H	α-helix	trans	-66.9	-35.3	177.2	-47	0	0	0	0	112.1	E326 Y333 G334 I335 V339 W340 S341	E326-S337 WeakPolarHBondContact OE1-CA 3.42Å; E326-S337 WeakPolarHBondContact OE1-CB 3.49Å; E326-S337 PolarHBondContact OE1-OG 3.45Å; Y333-S337 WeakPolarHBondContact CB-OG 3.47Å; G334-S337 PolarHBondContact N-OG 2.83Å; G334-S337 VanDerWaalsContact O-CB 3.3Å; G334-S337 WeakPolarHBondContact O-CB 3.24Å; G334-S337 PolarHBondContact O-N 3.22Å; G334-S337 PolarHBondContact O-OG 3.33Å; I335-S337 PolarHBondContact O-N 3.31Å; S337-V339 VanDerWaalsContact C-N 3.3Å; S337-W340 PolarHBondContact O-N 3.02Å; S337-S341 PolarHBondContact O-N 3.39Å; S337-S341 PolarHBondContact O-OG 3.39Å
338	D	95.2	Very high	90.9	Very high	4 Å²	4	33 Å²	33	2%	0.021	19%	0.185	C	C	.	.	H	α-helix	trans	-68.7	-31.6	172.4	-68.5	-29	0	0	0	111.4	L271 H281 R282 V284 I335 H336 S341 L342	L271-D338 HydrophobicContact CD2-CB 4.24Å; H281-D338 PolarHBondContact N-OD2 3.39Å; R282-D338 WeakPolarHBondContact CA-OD1 3.4Å; R282-D338 PolarHBondContact N-OD1 3.41Å; V284-D338 HydrophobicContact CG2-CB 3.98Å; I335-D338 HydrophobicContact CD1-CB 4.43Å; I335-D338 WeakPolarHBondContact O-CB 3.41Å; I335-D338 PolarHBondContact O-N 2.77Å; H336-D338 VanDerWaalsContact C-N 3.33Å; H336-D338 PolarHBondContact O-N 3.17Å; D338-S341 PolarHBondContact O-N 3.45Å; D338-L342 WeakPolarHBondContact O-CB 3.3Å; D338-L342 PolarHBondContact O-N 3.03Å
339	V	98.1	Very high	91.5	Very high	0 Å²	0	31.2 Å²	31.2	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-68.5	-36	175.2	173.1	0	0	0	0	112	I335 H336 S337 L342 G343 C399 R407 P410 L413	I335-V339 PolarHBondContact O-N 3.09Å; H336-V339 WeakPolarHBondContact O-CB 3.45Å; H336-V339 PolarHBondContact O-N 3.05Å; H336-V339 VanDerWaalsContact O-N 3.15Å; S337-V339 VanDerWaalsContact C-N 3.3Å; V339-L342 WeakPolarHBondContact O-CB 3.45Å; V339-L342 PolarHBondContact O-N 2.99Å; V339-G343 PolarHBondContact O-N 2.89Å; V339-C399 HydrophobicContact CG1-CB 4.04Å; V339-C399 WeakPolarHBondContact O-CB 3.25Å; V339-R407 HydrophobicContact CG1-CB 4.34Å; V339-P410 HydrophobicContact CG2-CG 4.11Å; V339-L413 HydrophobicContact CG1-CD1 3.92Å; V339-L413 HydrophobicContact CG2-CD1 4.09Å
340	W	97.6	Very high	92.3	Very high	0 Å²	0	28.1 Å²	28.1	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-61.1	-50.7	170.2	172	-80.7	0	0	0	111.5	M323 A324 P325 H336 S337 L342 G343 I344 I375 S380 C399 M400 K402	M323-W340 PolarHBondContact O-NE1 3.13Å; A324-W340 VanDerWaalsContact CA-CD1 3.41Å; A324-W340 HydrophobicContact CB-CB 3.68Å; A324-W340 HydrophobicContact CB-CD2 4.39Å; A324-W340 HydrophobicContact CB-CG 3.69Å; P325-W340 HydrophobicContact CG-CD2 4.38Å; P325-W340 HydrophobicContact CG-CE3 4.16Å; P325-W340 HydrophobicContact CG-CH2 3.67Å; P325-W340 HydrophobicContact CG-CZ2 3.9Å; P325-W340 HydrophobicContact CG-CZ3 3.79Å; H336-W340 PolarHBondContact O-N 3.1Å; S337-W340 PolarHBondContact O-N 3.02Å; W340-L342 PolarHBondContact O-N 3.32Å; W340-G343 WeakPolarHBondContact O-CA 3.32Å; W340-G343 PolarHBondContact O-N 2.7Å; W340-I344 HydrophobicContact CZ2-CD1 4.28Å; W340-I344 PolarHBondContact O-N 2.99Å; W340-I375 HydrophobicContact CZ2-CG2 3.91Å; W340-S380 WeakPolarHBondContact CH2-OG 3.2Å; W340-C399 WeakPolarHBondContact CA-O 3.42Å; W340-M400 HydrophobicContact CE3-CB 4.47Å; W340-M400 HydrophobicContact CZ3-CB 4.35Å; W340-M400 WeakPolarHBondContact CZ3-O 3.33Å; W340-K402 HydrophobicContact CH2-CD 3.94Å; W340-K402 HydrophobicContact CZ3-CD 4.07Å
341	S	96.6	Very high	93.2	Very high	4 Å²	4	26.2 Å²	26.2	3%	0.028	13%	0.127	C	C	.	.	H	α-helix	trans	-59.7	-35.7	179.4	-60	0	0	0	0	111.8	V284 Y322 S337 D338 S345	V284-S341 WeakPolarHBondContact O-CB 3.17Å; Y322-S341 WeakPolarHBondContact O-CA 3.38Å; Y322-S341 WeakPolarHBondContact O-CB 3.45Å; Y322-S341 PolarHBondContact O-OG 2.96Å; S337-S341 PolarHBondContact O-N 3.39Å; S337-S341 PolarHBondContact O-OG 3.39Å; D338-S341 PolarHBondContact O-N 3.45Å; S341-S345 WeakPolarHBondContact O-CB 3.41Å; S341-S345 PolarHBondContact O-N 3.19Å; S341-S345 PolarHBondContact O-OG 2.93Å
342	L	98.1	Very high	93.9	Very high	0 Å²	0	22.8 Å²	22.8	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-58.6	-50.7	169.4	177.9	71.1	0	0	0	111.8	V267 V268 L271 V284 D338 V339 W340 I344 S345 F346 F395 L413	V267-L342 HydrophobicContact CB-CD1 4.19Å; V267-L342 HydrophobicContact CG1-CD1 3.41Å; V267-L342 VanDerWaalsContact CG1-CD1 3.41Å; V268-L342 HydrophobicContact CG2-CD2 3.88Å; L271-L342 HydrophobicContact CD1-CB 4.5Å; L271-L342 HydrophobicContact CD1-CD2 4.32Å; V284-L342 HydrophobicContact CG1-CB 4.43Å; D338-L342 WeakPolarHBondContact O-CB 3.3Å; D338-L342 PolarHBondContact O-N 3.03Å; V339-L342 WeakPolarHBondContact O-CB 3.45Å; V339-L342 PolarHBondContact O-N 2.99Å; W340-L342 PolarHBondContact O-N 3.32Å; L342-I344 PolarHBondContact O-N 3.43Å; L342-S345 WeakPolarHBondContact O-CB 3.04Å; L342-S345 PolarHBondContact O-N 2.96Å; L342-F346 HydrophobicContact CD1-CD2 3.52Å; L342-F346 HydrophobicContact CD1-CE2 3.35Å; L342-F346 HydrophobicContact CD1-CZ 4.43Å; L342-F346 HydrophobicContact CG-CD2 4.19Å; L342-F346 HydrophobicContact CG-CE2 4.44Å; L342-F346 WeakPolarHBondContact O-CD2 3.33Å; L342-F346 PolarHBondContact O-N 3.34Å; L342-F395 HydrophobicContact CD2-CZ 3.99Å; L342-L413 HydrophobicContact CD2-CD1 3.99Å
343	G	98	Very high	94.7	Very high	0 Å²	0	23.1 Å²	23.1	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-56.4	-50.2	179.3	0	0	0	0	0	112.7	V339 W340 S345 F346 M347 M400	V339-G343 PolarHBondContact O-N 2.89Å; W340-G343 WeakPolarHBondContact O-CA 3.32Å; W340-G343 PolarHBondContact O-N 2.7Å; G343-S345 VanDerWaalsContact C-N 3.33Å; G343-S345 PolarHBondContact O-N 3.27Å; G343-F346 PolarHBondContact O-N 3.36Å; G343-M347 WeakPolarHBondContact O-CB 3.47Å; G343-M347 PolarHBondContact O-N 3.07Å; G343-M400 VanDerWaalsContact C-SD 3.59Å
344	I	96.4	Very high	95.2	Very high	0 Å²	0	20.1 Å²	20.1	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-58.8	-45.9	177	-63.1	-72.9	0	0	0	111.2	Y322 W340 L342 F346 M347 E348 F354 P355 Y356 M400	Y322-I344 HydrophobicContact CD1-CB 4.2Å; Y322-I344 HydrophobicContact CD1-CG2 3.55Å; Y322-I344 HydrophobicContact CE1-CG2 3.93Å; Y322-I344 HydrophobicContact CG-CG2 4.46Å; W340-I344 HydrophobicContact CZ2-CD1 4.28Å; W340-I344 PolarHBondContact O-N 2.99Å; L342-I344 PolarHBondContact O-N 3.43Å; I344-F346 PolarHBondContact O-N 3.24Å; I344-M347 PolarHBondContact O-N 3.4Å; I344-E348 WeakPolarHBondContact O-CB 3.13Å; I344-E348 PolarHBondContact O-N 3.03Å; I344-F354 HydrophobicContact CG2-CE2 3.74Å; I344-F354 HydrophobicContact CG2-CZ 4.1Å; I344-P355 HydrophobicContact CD1-CG 4.3Å; I344-P355 HydrophobicContact CG2-CG 4.17Å; I344-Y356 HydrophobicContact CD1-CD2 4.38Å; I344-Y356 HydrophobicContact CD1-CE2 3.67Å; I344-M400 HydrophobicContact CD1-CE 3.24Å; I344-M400 HydrophobicContact CD1-SD 3.91Å; I344-M400 HydrophobicContact CG1-CE 4.17Å; I344-M400 HydrophobicContact CG1-SD 4.32Å
345	S	97.1	Very high	95.4	Very high	0 Å²	0	20 Å²	20	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-60.2	-46.9	-178.8	-59.1	0	0	0	0	111.8	K285 S341 L342 G343 E348 L349	K285-S345 WeakPolarHBondContact CA-OG 3.32Å; S341-S345 WeakPolarHBondContact O-CB 3.41Å; S341-S345 PolarHBondContact O-N 3.19Å; S341-S345 PolarHBondContact O-OG 2.93Å; L342-S345 WeakPolarHBondContact O-CB 3.04Å; L342-S345 PolarHBondContact O-N 2.96Å; G343-S345 VanDerWaalsContact C-N 3.33Å; G343-S345 PolarHBondContact O-N 3.27Å; S345-E348 PolarHBondContact O-N 2.68Å; S345-L349 VanDerWaalsContact O-CG 3.28Å; S345-L349 WeakPolarHBondContact O-CG 3.49Å; S345-L349 PolarHBondContact O-N 2.87Å
346	F	98.1	Very high	95.1	Very high	0 Å²	0	20 Å²	20	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-74	-30.7	-178.2	-85	-98	0	0	0	112.5	L260 I263 A264 V267 M289 L342 G343 I344 A350 I396	L260-F346 HydrophobicContact CB-CD1 4.3Å; L260-F346 HydrophobicContact CB-CE1 4.43Å; L260-F346 HydrophobicContact CD2-CD1 4.04Å; L260-F346 HydrophobicContact CD2-CE1 4.13Å; L260-F346 WeakPolarHBondContact O-CE1 3.44Å; I263-F346 HydrophobicContact CB-CE1 4.26Å; I263-F346 HydrophobicContact CB-CZ 4.31Å; I263-F346 HydrophobicContact CG2-CE1 4.17Å; I263-F346 HydrophobicContact CG2-CZ 3.81Å; A264-F346 HydrophobicContact CB-CD1 4.02Å; A264-F346 HydrophobicContact CB-CE1 3.45Å; A264-F346 VanDerWaalsContact CB-CE1 3.45Å; A264-F346 HydrophobicContact CB-CZ 3.76Å; V267-F346 HydrophobicContact CB-CE2 4.38Å; V267-F346 HydrophobicContact CB-CZ 4.44Å; V267-F346 HydrophobicContact CG1-CE2 4.48Å; V267-F346 HydrophobicContact CG2-CE2 4.27Å; V267-F346 HydrophobicContact CG2-CZ 4.17Å; M289-F346 HydrophobicContact CE-CE2 4.2Å; M289-F346 HydrophobicContact SD-CE2 4.14Å; L342-F346 HydrophobicContact CD1-CD2 3.52Å; L342-F346 HydrophobicContact CD1-CE2 3.35Å; L342-F346 HydrophobicContact CD1-CZ 4.43Å; L342-F346 HydrophobicContact CG-CD2 4.19Å; L342-F346 HydrophobicContact CG-CE2 4.44Å; L342-F346 WeakPolarHBondContact O-CD2 3.33Å; L342-F346 PolarHBondContact O-N 3.34Å; G343-F346 PolarHBondContact O-N 3.36Å; I344-F346 PolarHBondContact O-N 3.24Å; F346-A350 WeakPolarHBondContact O-CB 3.31Å; F346-A350 PolarHBondContact O-N 2.98Å; F346-I396 HydrophobicContact CB-CD1 3.62Å
347	M	97.3	Very high	93.9	Very high	4 Å²	4	21.5 Å²	21.5	2%	0.02	11%	0.114	C	C	.	.	H	α-helix	trans	-64.5	-44.6	170.1	-170.4	174.7	-179.1	0	0	111.3	G343 I344 A350 L351 P355 P381 V382 L383 I396 M400	G343-M347 WeakPolarHBondContact O-CB 3.47Å; G343-M347 PolarHBondContact O-N 3.07Å; I344-M347 PolarHBondContact O-N 3.4Å; M347-A350 PolarHBondContact O-N 3.24Å; M347-L351 HydrophobicContact CE-CD1 3.79Å; M347-L351 HydrophobicContact CG-CD1 3.84Å; M347-L351 HydrophobicContact CG-CG 4.42Å; M347-L351 WeakPolarHBondContact O-CB 3.43Å; M347-L351 VanDerWaalsContact O-CG 3.25Å; M347-L351 WeakPolarHBondContact O-CG 3.28Å; M347-L351 PolarHBondContact O-N 3.28Å; M347-P355 HydrophobicContact CB-CB 4.5Å; M347-P355 HydrophobicContact CB-CG 4.47Å; M347-P355 HydrophobicContact CE-CB 3.79Å; M347-P355 HydrophobicContact CG-CB 3.84Å; M347-P355 HydrophobicContact CG-CG 4.34Å; M347-P355 HydrophobicContact SD-CB 3.51Å; M347-P355 VanDerWaalsContact SD-CB 3.51Å; M347-P355 HydrophobicContact SD-CG 4.15Å; M347-P381 HydrophobicContact CE-CB 3.84Å; M347-P381 HydrophobicContact CE-CG 4.32Å; M347-P381 HydrophobicContact SD-CB 4.19Å; M347-P381 HydrophobicContact SD-CG 4.01Å; M347-V382 WeakPolarHBondContact CE-O 3.34Å; M347-L383 HydrophobicContact CE-CD2 4.31Å; M347-L383 HydrophobicContact CE-CG 4.48Å; M347-L383 HydrophobicContact CG-CD2 3.82Å; M347-L383 HydrophobicContact CG-CG 4.37Å; M347-I396 HydrophobicContact CB-CG2 4.18Å; M347-I396 HydrophobicContact SD-CG2 4.37Å; M347-M400 HydrophobicContact SD-CE 4.32Å; M347-M400 HydrophobicContact SD-SD 4.15Å
348	E	95.9	Very high	92.3	Very high	38 Å²	38	26.8 Å²	26.8	18%	0.178	14%	0.139	C	C	.	.	H	α-helix	trans	-59.3	-50.2	175.4	173.5	175.8	-164.7	0	0	112.1	Y322 I344 S345 A350 L351 G352 R353	Y322-E348 WeakPolarHBondContact CE1-OE2 3.25Å; Y322-E348 VanDerWaalsContact CZ-OE2 3.23Å; Y322-E348 PolarHBondContact OH-OE1 3.14Å; Y322-E348 PolarHBondContact OH-OE2 2.79Å; I344-E348 WeakPolarHBondContact O-CB 3.13Å; I344-E348 PolarHBondContact O-N 3.03Å; S345-E348 PolarHBondContact O-N 2.68Å; E348-A350 VanDerWaalsContact C-N 3.27Å; E348-A350 PolarHBondContact O-N 2.58Å; E348-L351 PolarHBondContact O-N 3.1Å; E348-G352 WeakPolarHBondContact O-CA 3.33Å; E348-G352 PolarHBondContact O-N 3.11Å; E348-R353 WeakPolarHBondContact CA-O 3.25Å; E348-R353 PolarHBondContact O-N 3.42Å
349	L	97.3	Very high	90	Very high	6 Å²	6	30.3 Å²	30.3	3%	0.031	16%	0.157	C	C	.	.	H	α-helix	trans	-64.4	-33.4	-179.2	-66.9	175.7	0	0	0	112.1	L249 K254 M255 L260 P286 S345	L249-L349 HydrophobicContact CB-CD1 4.19Å; L249-L349 HydrophobicContact CB-CD2 4.35Å; L249-L349 HydrophobicContact CD1-CD1 3.94Å; K254-L349 WeakPolarHBondContact CA-O 3.43Å; M255-L349 HydrophobicContact CE-CD1 4.12Å; M255-L349 HydrophobicContact CE-CD2 3.51Å; M255-L349 HydrophobicContact CE-CG 4.26Å; M255-L349 HydrophobicContact CG-CB 4.47Å; M255-L349 PolarHBondContact N-O 2.9Å; M255-L349 HydrophobicContact SD-CB 4.41Å; M255-L349 HydrophobicContact SD-CD1 4.37Å; M255-L349 HydrophobicContact SD-CD2 4.43Å; L260-L349 HydrophobicContact CD2-CB 3.66Å; L260-L349 HydrophobicContact CD2-CD1 4.1Å; P286-L349 HydrophobicContact CB-CD1 4.47Å; P286-L349 HydrophobicContact CB-CD2 4.01Å; P286-L349 HydrophobicContact CB-CG 4.38Å; P286-L349 HydrophobicContact CG-CD1 4.34Å; P286-L349 HydrophobicContact CG-CD2 4.1Å; P286-L349 HydrophobicContact CG-CG 4.05Å; S345-L349 VanDerWaalsContact O-CG 3.28Å; S345-L349 WeakPolarHBondContact O-CG 3.49Å; S345-L349 PolarHBondContact O-N 2.87Å
350	A	97.3	Very high	87.2	Confident	0 Å²	0	38.1 Å²	38.1	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-71.9	-35.6	175.3	0	0	0	0	0	113.2	K254 L260 F346 M347 E348 F388 F392	K254-A350 WeakPolarHBondContact CE-O 3.31Å; K254-A350 WeakPolarHBondContact CG-O 3.41Å; L260-A350 HydrophobicContact CD1-CB 3.66Å; F346-A350 WeakPolarHBondContact O-CB 3.31Å; F346-A350 PolarHBondContact O-N 2.98Å; M347-A350 PolarHBondContact O-N 3.24Å; E348-A350 VanDerWaalsContact C-N 3.27Å; E348-A350 PolarHBondContact O-N 2.58Å; A350-F388 HydrophobicContact CB-CE1 3.77Å; A350-F388 HydrophobicContact CB-CZ 3.97Å; A350-F392 HydrophobicContact CB-CE1 3.6Å; A350-F392 HydrophobicContact CB-CZ 3.78Å
351	L	95.1	Very high	84.6	Confident	30 Å²	30	47.5 Å²	47.5	16%	0.157	23%	0.234	C	C	.	.	H	α-helix	trans	-86.4	-21.9	179.2	-64.8	176.1	0	0	0	112.6	M347 E348 R353 P355 L383 P384 F388	M347-L351 HydrophobicContact CE-CD1 3.79Å; M347-L351 HydrophobicContact CG-CD1 3.84Å; M347-L351 HydrophobicContact CG-CG 4.42Å; M347-L351 WeakPolarHBondContact O-CB 3.43Å; M347-L351 VanDerWaalsContact O-CG 3.25Å; M347-L351 WeakPolarHBondContact O-CG 3.28Å; M347-L351 PolarHBondContact O-N 3.28Å; E348-L351 PolarHBondContact O-N 3.1Å; L351-R353 HydrophobicContact CB-CG 4.09Å; L351-R353 PolarHBondContact O-N 3.03Å; L351-P355 HydrophobicContact CD1-CB 4.32Å; L351-L383 HydrophobicContact CD2-CD2 4.1Å; L351-L383 HydrophobicContact CG-CD2 4.19Å; L351-P384 HydrophobicContact CD2-CG 3.93Å; L351-F388 HydrophobicContact CD2-CE2 4.05Å; L351-F388 HydrophobicContact CD2-CZ 4.21Å
352	G	93.6	Very high	81.9	Confident	41 Å²	41	54.4 Å²	54.4	42%	0.423	27%	0.271	S	S	.	.	T	Hydrogen-bonded Turn	trans	70.6	14.1	-169.7	0	0	0	0	0	113.8	E348	E348-G352 WeakPolarHBondContact O-CA 3.33Å; E348-G352 PolarHBondContact O-N 3.11Å
353	R	91.2	Very high	79.1	Confident	181 Å²	181	62.5 Å²	62.5	68%	0.683	31%	0.308	S	S	*	.	S	Bend	trans	-153.3	150.3	177.9	64.1	178.9	-178.2	-177.6	-0	109.6	E348 L351	E348-R353 WeakPolarHBondContact CA-O 3.25Å; E348-R353 PolarHBondContact O-N 3.42Å; L351-R353 HydrophobicContact CB-CG 4.09Å; L351-R353 PolarHBondContact O-N 3.03Å
354	F	90.9	Very high	76.6	Confident	26 Å²	26	64.8 Å²	64.8	11%	0.114	33%	0.332	C	S	.	.			trans	-57.7	135.4	175.6	-166	-102.9	0	0	0	111	A321 Y322 I344 Y356 Q358 L371	A321-F354 HydrophobicContact CB-CE1 4.3Å; A321-F354 HydrophobicContact CB-CE2 4.07Å; A321-F354 HydrophobicContact CB-CZ 3.64Å; A321-F354 WeakPolarHBondContact O-CZ 3.46Å; Y322-F354 HydrophobicContact CD1-CE2 4.31Å; Y322-F354 HydrophobicContact CE1-CD2 4.35Å; Y322-F354 AromaticContact CE1-CE2 3.87Å; Y322-F354 HydrophobicContact CE1-CE2 3.87Å; Y322-F354 HydrophobicContact CE2-CE2 4.4Å; Y322-F354 AromaticContact CZ-CE2 3.92Å; I344-F354 HydrophobicContact CG2-CE2 3.74Å; I344-F354 HydrophobicContact CG2-CZ 4.1Å; F354-Y356 AromaticContact CE1-CD2 3.82Å; F354-Y356 HydrophobicContact CE1-CD2 3.82Å; F354-Y356 HydrophobicContact CE1-CG 4.24Å; F354-Y356 HydrophobicContact CZ-CD2 4.21Å; F354-Q358 HydrophobicContact CB-CG 4.33Å; F354-Q358 VanDerWaalsContact CD1-NE2 3.32Å; F354-L371 HydrophobicContact CE1-CD1 4.21Å; F354-L371 HydrophobicContact CE1-CD2 4.27Å
355	P	89.4	Confident	74.3	Confident	21 Å²	21	68.8 Å²	68.8	14%	0.136	36%	0.36	C	S	.	.	S	Bend	trans	-76.8	-23.5	-166.6	28.2	-35.8	0	0	0	114.6	I344 M347 L351 P381	I344-P355 HydrophobicContact CD1-CG 4.3Å; I344-P355 HydrophobicContact CG2-CG 4.17Å; M347-P355 HydrophobicContact CB-CB 4.5Å; M347-P355 HydrophobicContact CB-CG 4.47Å; M347-P355 HydrophobicContact CE-CB 3.79Å; M347-P355 HydrophobicContact CG-CB 3.84Å; M347-P355 HydrophobicContact CG-CG 4.34Å; M347-P355 HydrophobicContact SD-CB 3.51Å; M347-P355 VanDerWaalsContact SD-CB 3.51Å; M347-P355 HydrophobicContact SD-CG 4.15Å; L351-P355 HydrophobicContact CD1-CB 4.32Å; P355-P381 HydrophobicContact CB-CB 4.22Å; P355-P381 HydrophobicContact CB-CG 3.92Å; P355-P381 HydrophobicContact CG-CG 4.33Å
356	Y	85.3	Confident	72.2	Confident	6 Å²	6	71.3 Å²	71.3	2%	0.024	37%	0.373	C	S	.	.	S	Bend	trans	-81.5	148.2	171.9	-72.5	-89.5	0	0	0	111	I344 F354 Q358 L371 I375 P381	I344-Y356 HydrophobicContact CD1-CD2 4.38Å; I344-Y356 HydrophobicContact CD1-CE2 3.67Å; F354-Y356 AromaticContact CE1-CD2 3.82Å; F354-Y356 HydrophobicContact CE1-CD2 3.82Å; F354-Y356 HydrophobicContact CE1-CG 4.24Å; F354-Y356 HydrophobicContact CZ-CD2 4.21Å; Y356-Q358 PolarHBondContact O-N 3.42Å; Y356-L371 HydrophobicContact CG-CD1 4Å; Y356-I375 HydrophobicContact CD2-CG1 4.2Å; Y356-I375 HydrophobicContact CE1-CG1 4.14Å; Y356-I375 HydrophobicContact CE2-CG1 3.76Å; Y356-P381 HydrophobicContact CD2-CG 4.26Å; Y356-P381 HydrophobicContact CE1-CG 4.39Å; Y356-P381 HydrophobicContact CE2-CG 3.91Å; Y356-P381 WeakPolarHBondContact OH-CD 3.44Å
357	P	69.9	Low	70.5	Confident	86 Å²	86	77.2 Å²	77.2	56%	0.558	40%	0.402	S	S	*	.			trans	-51.7	113.8	-179.9	-24.9	33	0	0	0	111.8	L366	P357-L366 WeakPolarHBondContact O-CD1 3.31Å
358	Q	60.1	Low	69.2	Low	116 Å²	116	80 Å²	80	54%	0.542	42%	0.421	S	S	.	.			trans	-91.4	94.7	163	-63	-66.3	-28.9	0	0	105.5	F354 Y356 Q360	F354-Q358 HydrophobicContact CB-CG 4.33Å; F354-Q358 VanDerWaalsContact CD1-NE2 3.32Å; Y356-Q358 PolarHBondContact O-N 3.42Å; Q358-Q360 PolarHBondContact O-N 3.25Å
359	I	46.7	Very low	68.2	Low	77 Å²	77	84.7 Å²	84.7	40%	0.395	45%	0.446	S	S	.	.			trans	-59	117.7	176.3	-60	178.4	0	0	0	106.9	Q363 L366	I359-Q363 HydrophobicContact CG2-CB 3.82Å; I359-L366 HydrophobicContact CD1-CD1 4.24Å; I359-L366 HydrophobicContact CD1-CG 4.21Å; I359-L366 HydrophobicContact CG1-CD1 4.17Å
360	Q	39.7	Very low	67.2	Low	164 Å²	164	88.9 Å²	88.9	77%	0.766	47%	0.466	S	S	*	.			trans	-55.5	153	-174.6	-65.2	177.6	16.7	0	0	110.3	Q358 N362 Q363	Q358-Q360 PolarHBondContact O-N 3.25Å; Q360-N362 PolarHBondContact O-N 3.04Å; Q360-Q363 PolarHBondContact O-N 3.35Å; Q360-Q363 VanDerWaalsContact O-N 3.07Å
361	K	43	Very low	66.6	Low	197 Å²	197	90 Å²	90	86%	0.857	47%	0.471	S	S	*	.	T	Hydrogen-bonded Turn	trans	-49	-2.7	-174.6	-68.3	-179	175	179.3	0	117.2
362	N	39	Very low	66.1	Low	150 Å²	150	89.7 Å²	89.7	80%	0.802	47%	0.47	S	S	*	.	T	Hydrogen-bonded Turn	trans	-103.1	-3.3	179.9	-64.8	-7.3	0	0	0	114.5	Q360	Q360-N362 PolarHBondContact O-N 3.04Å
363	Q	40.5	Very low	65.6	Low	169 Å²	169	93.3 Å²	93.3	79%	0.79	48%	0.476	S	S	*	.	S	Bend	trans	-138.9	39.7	175	-69.9	-168	16.2	0	0	114.1	I359 Q360	I359-Q363 HydrophobicContact CG2-CB 3.82Å; Q360-Q363 PolarHBondContact O-N 3.35Å; Q360-Q363 VanDerWaalsContact O-N 3.07Å
364	G	44.3	Very low	65.4	Low	48 Å²	48	86.1 Å²	86.1	50%	0.495	45%	0.453	S	S	.	.			trans	73.1	117.6	176.8	0	0	0	0	0	112.2	L366	G364-L366 PolarHBondContact O-N 3.14Å
365	S	48.6	Very low	65.4	Low	84 Å²	84	84.9 Å²	84.9	59%	0.587	45%	0.448	S	S	*	.	P	Polyproline II helix	trans	-56.2	134.5	167.1	-60	0	0	0	0	108.8	M367	S365-M367 PolarHBondContact O-N 3.46Å; S365-M367 VanDerWaalsContact O-N 3.11Å
366	L	53	Low	65.3	Low	53 Å²	53	85.9 Å²	85.9	28%	0.277	45%	0.453	S	S	.	.	P	Polyproline II helix	trans	-49.7	124.9	165.9	-86.9	145.6	0	0	0	107.2	P357 I359 G364 Q370	P357-L366 WeakPolarHBondContact O-CD1 3.31Å; I359-L366 HydrophobicContact CD1-CD1 4.24Å; I359-L366 HydrophobicContact CD1-CG 4.21Å; I359-L366 HydrophobicContact CG1-CD1 4.17Å; G364-L366 PolarHBondContact O-N 3.14Å; L366-Q370 HydrophobicContact CB-CB 4.33Å; L366-Q370 HydrophobicContact CD2-CB 3.28Å; L366-Q370 HydrophobicContact CD2-CG 4.21Å; L366-Q370 HydrophobicContact CG-CB 4.4Å
367	M	62.2	Low	65.4	Low	125 Å²	125	90.4 Å²	90.4	62%	0.616	48%	0.478	S	S	*	.	P	Polyproline II helix	trans	-58.3	142.9	172.7	-68.9	-63	-71.8	0	0	107.4	S365 L369 Q370 L371	S365-M367 PolarHBondContact O-N 3.46Å; S365-M367 VanDerWaalsContact O-N 3.11Å; M367-L369 PolarHBondContact O-N 3.1Å; M367-Q370 HydrophobicContact CB-CG 4.31Å; M367-Q370 WeakPolarHBondContact O-CB 3.27Å; M367-Q370 PolarHBondContact O-N 2.83Å; M367-L371 PolarHBondContact O-N 2.98Å
368	P	70.3	Confident	66.4	Low	62 Å²	62	92 Å²	92	40%	0.403	48%	0.478	S	S	.	.	H	α-helix	trans	-45.2	-36.8	-178	-31.4	33.7	0	0	0	114.1	V317 L371 L372	V317-P368 HydrophobicContact CG1-CB 4.26Å; V317-P368 HydrophobicContact CG1-CG 3.64Å; P368-L371 PolarHBondContact O-N 3.17Å; P368-L372 WeakPolarHBondContact O-CG 3.37Å; P368-L372 PolarHBondContact O-N 3.47Å
369	L	74.1	Confident	67.8	Low	136 Å²	136	93.6 Å²	93.6	71%	0.712	49%	0.49	S	S	*	.	H	α-helix	trans	-64	-38.8	175.6	-66	174.2	0	0	0	114.1	M367 L371 L372 Q373	M367-L369 PolarHBondContact O-N 3.1Å; L369-L371 VanDerWaalsContact C-N 3.34Å; L369-L372 PolarHBondContact O-N 2.99Å; L369-Q373 WeakPolarHBondContact O-CB 3.31Å; L369-Q373 PolarHBondContact O-N 3.47Å
370	Q	78.1	Confident	70	Confident	94 Å²	94	91.2 Å²	91.2	44%	0.439	48%	0.48	S	S	.	.	H	α-helix	trans	-69.3	-34.4	-179.9	-62.9	174.4	-46.4	0	0	111.7	L366 M367 Q373 C374	L366-Q370 HydrophobicContact CB-CB 4.33Å; L366-Q370 HydrophobicContact CD2-CB 3.28Å; L366-Q370 HydrophobicContact CD2-CG 4.21Å; L366-Q370 HydrophobicContact CG-CB 4.4Å; M367-Q370 HydrophobicContact CB-CG 4.31Å; M367-Q370 WeakPolarHBondContact O-CB 3.27Å; M367-Q370 PolarHBondContact O-N 2.83Å; Q370-Q373 PolarHBondContact O-N 3.48Å; Q370-C374 WeakPolarHBondContact O-CB 3.39Å; Q370-C374 PolarHBondContact O-N 3.23Å
371	L	83.3	Confident	72.5	Confident	23 Å²	23	84.8 Å²	84.8	12%	0.12	45%	0.453	C	S	.	.	H	α-helix	trans	-64.1	-45	172	174.7	61.1	0	0	0	110.8	A321 F354 Y356 M367 P368 L369 Q373 C374 I375	A321-L371 HydrophobicContact CB-CD2 3.73Å; F354-L371 HydrophobicContact CE1-CD1 4.21Å; F354-L371 HydrophobicContact CE1-CD2 4.27Å; Y356-L371 HydrophobicContact CG-CD1 4Å; M367-L371 PolarHBondContact O-N 2.98Å; P368-L371 PolarHBondContact O-N 3.17Å; L369-L371 VanDerWaalsContact C-N 3.34Å; L371-Q373 VanDerWaalsContact C-N 3.29Å; L371-Q373 PolarHBondContact O-N 2.69Å; L371-C374 WeakPolarHBondContact O-CB 3.49Å; L371-C374 PolarHBondContact O-N 3.3Å; L371-I375 HydrophobicContact CD1-CD1 4.19Å; L371-I375 HydrophobicContact CD1-CG1 4.35Å; L371-I375 HydrophobicContact CG-CD1 4.02Å; L371-I375 WeakPolarHBondContact O-CG1 3.36Å; L371-I375 PolarHBondContact O-N 3.13Å
372	L	85.2	Confident	74.9	Confident	25 Å²	25	80.9 Å²	80.9	13%	0.131	45%	0.445	C	S	.	.	H	α-helix	trans	-62.1	-40.8	177	-62.3	179.7	0	0	0	111.6	N320 I328 P368 L369 I375 V376	N320-L372 HydrophobicContact CB-CD1 4.15Å; N320-L372 HydrophobicContact CB-CD2 3.53Å; N320-L372 HydrophobicContact CB-CG 4.42Å; N320-L372 WeakPolarHBondContact O-CD2 3.44Å; I328-L372 HydrophobicContact CD1-CB 4.27Å; I328-L372 HydrophobicContact CD1-CD2 3.7Å; I328-L372 HydrophobicContact CG1-CD2 4.12Å; I328-L372 HydrophobicContact CG2-CB 3.93Å; P368-L372 WeakPolarHBondContact O-CG 3.37Å; P368-L372 PolarHBondContact O-N 3.47Å; L369-L372 PolarHBondContact O-N 2.99Å; L372-I375 HydrophobicContact CD2-CD1 4.41Å; L372-I375 PolarHBondContact O-N 2.76Å; L372-V376 WeakPolarHBondContact O-CG2 3.04Å; L372-V376 PolarHBondContact O-N 3.42Å
373	Q	83.6	Confident	77.5	Confident	116 Å²	116	74.2 Å²	74.2	54%	0.542	41%	0.409	S	S	.	.	H	α-helix	trans	-61.1	-45.3	174.2	-171.1	172.7	2.6	0	0	111.5	L369 Q370 L371 I375 V376 D377	L369-Q373 WeakPolarHBondContact O-CB 3.31Å; L369-Q373 PolarHBondContact O-N 3.47Å; Q370-Q373 PolarHBondContact O-N 3.48Å; L371-Q373 VanDerWaalsContact C-N 3.29Å; L371-Q373 PolarHBondContact O-N 2.69Å; Q373-I375 VanDerWaalsContact C-N 3.32Å; Q373-I375 PolarHBondContact O-N 3.21Å; Q373-V376 PolarHBondContact O-N 2.67Å; Q373-D377 WeakPolarHBondContact CG-OD2 3.44Å; Q373-D377 PolarHBondContact NE2-OD2 2.92Å; Q373-D377 VanDerWaalsContact NE2-OD2 3.07Å; Q373-D377 WeakPolarHBondContact O-CB 3.43Å; Q373-D377 PolarHBondContact O-N 3.07Å
374	C	86.9	Confident	80	Confident	31 Å²	31	68.2 Å²	68.2	21%	0.209	39%	0.385	C	S	.	.	H	α-helix	trans	-60.3	-40.5	174.6	-177.9	0	0	0	0	112.1	Q370 L371 V376 E378	Q370-C374 WeakPolarHBondContact O-CB 3.39Å; Q370-C374 PolarHBondContact O-N 3.23Å; L371-C374 WeakPolarHBondContact O-CB 3.49Å; L371-C374 PolarHBondContact O-N 3.3Å; C374-V376 PolarHBondContact O-N 3.26Å; C374-E378 HydrophobicContact CB-CG 4.38Å; C374-E378 WeakPolarHBondContact O-CB 3.19Å; C374-E378 PolarHBondContact O-N 3.12Å; C374-E378 VanDerWaalsContact O-N 3.09Å
375	I	89.8	Confident	82.2	Confident	0 Å²	0	73.1 Å²	73.1	0%	0	41%	0.405	C	S	.	.	H	α-helix	trans	-63.4	-27.5	174.9	-68	164.1	0	0	0	111.8	A321 P325 I328 W340 Y356 L371 L372 Q373 K402	A321-I375 VanDerWaalsContact O-CD1 3.32Å; A321-I375 WeakPolarHBondContact O-CD1 3.34Å; P325-I375 HydrophobicContact CG-CG2 4.2Å; P325-I375 WeakPolarHBondContact CG-O 3.32Å; I328-I375 HydrophobicContact CD1-CB 3.84Å; I328-I375 HydrophobicContact CD1-CD1 4.31Å; I328-I375 HydrophobicContact CD1-CG2 3.49Å; I328-I375 VanDerWaalsContact CD1-CG2 3.49Å; W340-I375 HydrophobicContact CZ2-CG2 3.91Å; Y356-I375 HydrophobicContact CD2-CG1 4.2Å; Y356-I375 HydrophobicContact CE1-CG1 4.14Å; Y356-I375 HydrophobicContact CE2-CG1 3.76Å; L371-I375 HydrophobicContact CD1-CD1 4.19Å; L371-I375 HydrophobicContact CD1-CG1 4.35Å; L371-I375 HydrophobicContact CG-CD1 4.02Å; L371-I375 WeakPolarHBondContact O-CG1 3.36Å; L371-I375 PolarHBondContact O-N 3.13Å; L372-I375 HydrophobicContact CD2-CD1 4.41Å; L372-I375 PolarHBondContact O-N 2.76Å; Q373-I375 VanDerWaalsContact C-N 3.32Å; Q373-I375 PolarHBondContact O-N 3.21Å; I375-K402 PolarHBondContact O-NZ 3.35Å
376	V	88.7	Confident	84.2	Confident	41 Å²	41	72.8 Å²	72.8	25%	0.248	42%	0.415	C	S	.	.	H	α-helix	trans	-86.1	-54.5	176.9	177.1	0	0	0	0	111	I328 L372 Q373 C374 K402	I328-V376 HydrophobicContact CB-CG2 3.84Å; I328-V376 HydrophobicContact CD1-CG2 4.34Å; I328-V376 HydrophobicContact CG2-CG2 3.59Å; L372-V376 WeakPolarHBondContact O-CG2 3.04Å; L372-V376 PolarHBondContact O-N 3.42Å; Q373-V376 PolarHBondContact O-N 2.67Å; C374-V376 PolarHBondContact O-N 3.26Å; V376-K402 PolarHBondContact O-NZ 2.87Å
377	D	87.3	Confident	86.2	Confident	101 Å²	101	75.8 Å²	75.8	54%	0.54	43%	0.428	S	S	.	.	H	α-helix	trans	-87	-35.3	-163.4	-62.7	-17	0	0	0	113.8	Q373	Q373-D377 WeakPolarHBondContact CG-OD2 3.44Å; Q373-D377 PolarHBondContact NE2-OD2 2.92Å; Q373-D377 VanDerWaalsContact NE2-OD2 3.07Å; Q373-D377 WeakPolarHBondContact O-CB 3.43Å; Q373-D377 PolarHBondContact O-N 3.07Å
378	E	89.2	Confident	87.9	Confident	121 Å²	121	71.1 Å²	71.1	57%	0.565	40%	0.404	S	S	*	.	S	Bend	trans	-91.8	158.9	-172.9	-61.4	-65.8	162.1	0	0	112.5	C374 K402	C374-E378 HydrophobicContact CB-CG 4.38Å; C374-E378 WeakPolarHBondContact O-CB 3.19Å; C374-E378 PolarHBondContact O-N 3.12Å; C374-E378 VanDerWaalsContact O-N 3.09Å; E378-K402 WeakPolarHBondContact O-CE 3.45Å; E378-K402 PolarHBondContact O-NZ 3.49Å
379	D	90	Very high	89.2	Confident	149 Å²	149	69.9 Å²	69.9	80%	0.797	40%	0.397	S	S	*	.	P	Polyproline II helix	trans	-57.5	146	174.5	-77.9	-34.5	0	0	0	112.6
380	S	92.9	Very high	90.3	Very high	27 Å²	27	71.4 Å²	71.4	19%	0.189	40%	0.4	C	S	.	.	P	Polyproline II helix	trans	-60.6	137	175.3	-64	0	0	0	0	110.3	W340 M400	W340-S380 WeakPolarHBondContact CH2-OG 3.2Å; S380-M400 WeakPolarHBondContact CB-O 3.44Å; S380-M400 PolarHBondContact OG-O 3.36Å
381	P	92.9	Very high	91.3	Very high	29 Å²	29	68.9 Å²	68.9	19%	0.188	39%	0.392	C	S	.	.	P	Polyproline II helix	trans	-64.1	146.4	179	28.5	-35.9	0	0	0	110.4	M347 P355 Y356 M400	M347-P381 HydrophobicContact CE-CB 3.84Å; M347-P381 HydrophobicContact CE-CG 4.32Å; M347-P381 HydrophobicContact SD-CB 4.19Å; M347-P381 HydrophobicContact SD-CG 4.01Å; P355-P381 HydrophobicContact CB-CB 4.22Å; P355-P381 HydrophobicContact CB-CG 3.92Å; P355-P381 HydrophobicContact CG-CG 4.33Å; Y356-P381 HydrophobicContact CD2-CG 4.26Å; Y356-P381 HydrophobicContact CE1-CG 4.39Å; Y356-P381 HydrophobicContact CE2-CG 3.91Å; Y356-P381 WeakPolarHBondContact OH-CD 3.44Å; P381-M400 HydrophobicContact CG-CE 3.61Å
382	V	93.3	Very high	92	Very high	115 Å²	115	67.8 Å²	67.8	70%	0.697	39%	0.386	S	S	*	.			trans	-113.2	148.7	-178.5	-62.7	0	0	0	0	111	M347	M347-V382 WeakPolarHBondContact CE-O 3.34Å
383	L	93.9	Very high	92.6	Very high	10 Å²	10	68.8 Å²	68.8	5%	0.052	39%	0.393	C	S	.	.	P	Polyproline II helix	trans	-67	145.6	173.9	-76.8	171.3	0	0	0	110.8	M347 L351 V385 F388 F392 V393 I396	M347-L383 HydrophobicContact CE-CD2 4.31Å; M347-L383 HydrophobicContact CE-CG 4.48Å; M347-L383 HydrophobicContact CG-CD2 3.82Å; M347-L383 HydrophobicContact CG-CG 4.37Å; L351-L383 HydrophobicContact CD2-CD2 4.1Å; L351-L383 HydrophobicContact CG-CD2 4.19Å; L383-V385 PolarHBondContact O-N 3Å; L383-F388 HydrophobicContact CB-CD2 4.07Å; L383-F388 HydrophobicContact CD1-CB 4.5Å; L383-F388 HydrophobicContact CD1-CD2 4.28Å; L383-F388 HydrophobicContact CD1-CG 4.32Å; L383-F388 HydrophobicContact CD2-CD2 3.95Å; L383-F388 HydrophobicContact CD2-CE2 3.79Å; L383-F388 HydrophobicContact CD2-CZ 4.27Å; L383-F388 HydrophobicContact CG-CD2 4.34Å; L383-F392 HydrophobicContact CD1-CD1 3.92Å; L383-F392 HydrophobicContact CD1-CE1 3.83Å; L383-F392 HydrophobicContact CD1-CZ 4.49Å; L383-V393 HydrophobicContact CB-CG2 4.24Å; L383-V393 HydrophobicContact CD1-CG2 4.11Å; L383-I396 HydrophobicContact CD1-CB 4.18Å; L383-I396 HydrophobicContact CD1-CG1 3.9Å; L383-I396 HydrophobicContact CD1-CG2 4.48Å
384	P	92.4	Very high	93.3	Very high	42 Å²	42	67.4 Å²	67.4	27%	0.273	39%	0.387	S	S	.	.	P	Polyproline II helix	trans	-54.6	134.9	173.9	-24.9	32	0	0	0	112.7	L351 G386 E387 F388	L351-P384 HydrophobicContact CD2-CG 3.93Å; P384-G386 PolarHBondContact O-N 3Å; P384-E387 HydrophobicContact CB-CB 4.28Å; P384-E387 HydrophobicContact CB-CG 4.05Å; P384-F388 HydrophobicContact CG-CE2 4.49Å
385	V	89.9	Confident	93.8	Very high	151 Å²	151	66 Å²	66	92%	0.915	38%	0.377	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.9	130.5	-179.8	-178.3	0	0	0	0	110.2	L383 E387	L383-V385 PolarHBondContact O-N 3Å; V385-E387 VanDerWaalsContact C-N 3.3Å; V385-E387 PolarHBondContact O-N 3.37Å
386	G	92	Very high	94.3	Very high	78 Å²	78	66.1 Å²	66.1	80%	0.804	38%	0.378	S	S	*	.	T	Hydrogen-bonded Turn	trans	80.9	-2.5	174.5	0	0	0	0	0	115.9	P384	P384-G386 PolarHBondContact O-N 3Å
387	E	95.2	Very high	94.7	Very high	116 Å²	116	66.8 Å²	66.8	54%	0.542	38%	0.382	S	S	.	.	T	Hydrogen-bonded Turn	trans	-88.6	-22.9	176.4	-74.7	-166.6	-143.5	0	0	113.9	K254 P384 V385	K254-E387 IonicContact NZ-OE2 3.95Å; P384-E387 HydrophobicContact CB-CB 4.28Å; P384-E387 HydrophobicContact CB-CG 4.05Å; V385-E387 VanDerWaalsContact C-N 3.3Å; V385-E387 PolarHBondContact O-N 3.37Å
388	F	97.1	Very high	95.2	Very high	27 Å²	27	64.1 Å²	64.1	12%	0.118	37%	0.366	C	S	.	.	S	Bend	trans	-130.7	156.7	-170.7	-64.4	-76.6	0	0	0	111.3	A350 L351 L383 P384 F392 V393	A350-F388 HydrophobicContact CB-CE1 3.77Å; A350-F388 HydrophobicContact CB-CZ 3.97Å; L351-F388 HydrophobicContact CD2-CE2 4.05Å; L351-F388 HydrophobicContact CD2-CZ 4.21Å; L383-F388 HydrophobicContact CB-CD2 4.07Å; L383-F388 HydrophobicContact CD1-CB 4.5Å; L383-F388 HydrophobicContact CD1-CD2 4.28Å; L383-F388 HydrophobicContact CD1-CG 4.32Å; L383-F388 HydrophobicContact CD2-CD2 3.95Å; L383-F388 HydrophobicContact CD2-CE2 3.79Å; L383-F388 HydrophobicContact CD2-CZ 4.27Å; L383-F388 HydrophobicContact CG-CD2 4.34Å; P384-F388 HydrophobicContact CG-CE2 4.49Å; F388-F392 HydrophobicContact CB-CD1 3.98Å; F388-F392 AromaticContact CD1-CD1 3.64Å; F388-F392 HydrophobicContact CD1-CD1 3.64Å; F388-F392 AromaticContact CD1-CE1 3.74Å; F388-F392 HydrophobicContact CD1-CE1 3.74Å; F388-F392 HydrophobicContact CE1-CD1 4.45Å; F388-F392 HydrophobicContact CE1-CE1 4.11Å; F388-F392 AromaticContact CG-CD1 3.99Å; F388-F392 HydrophobicContact CG-CD1 3.99Å; F388-F392 HydrophobicContact CG-CE1 4.3Å; F388-V393 HydrophobicContact CB-CG2 3.89Å
389	S	97.8	Very high	95.6	Very high	35 Å²	35	58.4 Å²	58.4	25%	0.245	34%	0.339	C	S	.	.			trans	-66.4	147.4	177.6	79.5	0	0	0	0	111.8	E257 P391 F392 V393	E257-S389 WeakPolarHBondContact OE1-CB 3.32Å; E257-S389 PolarHBondContact OE1-OG 3.39Å; E257-S389 PolarHBondContact OE2-N 3.11Å; S389-P391 VanDerWaalsContact C-N 3.33Å; S389-P391 WeakPolarHBondContact OG-CD 3.48Å; S389-F392 PolarHBondContact O-N 3.47Å; S389-F392 WeakPolarHBondContact OG-CB 3.36Å; S389-F392 PolarHBondContact OG-N 2.77Å; S389-V393 WeakPolarHBondContact O-CG2 3.22Å; S389-V393 PolarHBondContact O-N 3.23Å
390	E	97.3	Very high	95.9	Very high	169 Å²	169	51.5 Å²	51.5	79%	0.79	30%	0.302	S	S	*	.	H	α-helix	trans	-55.1	-42.1	175.5	-63.7	179.8	173.2	0	0	112.8	F392 V393 H394	E390-F392 VanDerWaalsContact C-N 3.31Å; E390-F392 PolarHBondContact O-N 2.9Å; E390-V393 PolarHBondContact O-N 3.45Å; E390-H394 VanDerWaalsContact O-CB 3.32Å; E390-H394 WeakPolarHBondContact O-CB 3.35Å; E390-H394 PolarHBondContact O-N 2.87Å
391	P	98.1	Very high	96.1	Very high	40 Å²	40	55 Å²	55	26%	0.26	31%	0.311	S	S	.	.	H	α-helix	trans	-57.8	-40.9	173.2	-26.6	35.7	0	0	0	113.3	S389 F395 H416 F418	S389-P391 VanDerWaalsContact C-N 3.33Å; S389-P391 WeakPolarHBondContact OG-CD 3.48Å; P391-F395 WeakPolarHBondContact O-CB 3.44Å; P391-F395 PolarHBondContact O-N 3.25Å; P391-H416 PolarHBondContact O-CE1 2.92Å; P391-F418 HydrophobicContact CB-CB 3.98Å; P391-F418 HydrophobicContact CB-CD2 4.36Å
392	F	98.4	Very high	96.1	Very high	0 Å²	0	55.9 Å²	55.9	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-70.4	-43.8	179.9	-175.2	-133.7	0	0	0	112	E257 L260 A350 L383 F388 S389 E390 H394 F395 I396 F418	E257-F392 HydrophobicContact CG-CB 4.11Å; E257-F392 HydrophobicContact CG-CD1 3.8Å; E257-F392 HydrophobicContact CG-CE1 4.41Å; E257-F392 HydrophobicContact CG-CG 3.93Å; L260-F392 HydrophobicContact CD1-CZ 4.38Å; A350-F392 HydrophobicContact CB-CE1 3.6Å; A350-F392 HydrophobicContact CB-CZ 3.78Å; L383-F392 HydrophobicContact CD1-CD1 3.92Å; L383-F392 HydrophobicContact CD1-CE1 3.83Å; L383-F392 HydrophobicContact CD1-CZ 4.49Å; F388-F392 HydrophobicContact CB-CD1 3.98Å; F388-F392 AromaticContact CD1-CD1 3.64Å; F388-F392 HydrophobicContact CD1-CD1 3.64Å; F388-F392 AromaticContact CD1-CE1 3.74Å; F388-F392 HydrophobicContact CD1-CE1 3.74Å; F388-F392 HydrophobicContact CE1-CD1 4.45Å; F388-F392 HydrophobicContact CE1-CE1 4.11Å; F388-F392 AromaticContact CG-CD1 3.99Å; F388-F392 HydrophobicContact CG-CD1 3.99Å; F388-F392 HydrophobicContact CG-CE1 4.3Å; S389-F392 PolarHBondContact O-N 3.47Å; S389-F392 WeakPolarHBondContact OG-CB 3.36Å; S389-F392 PolarHBondContact OG-N 2.77Å; E390-F392 VanDerWaalsContact C-N 3.31Å; E390-F392 PolarHBondContact O-N 2.9Å; F392-H394 VanDerWaalsContact C-N 3.31Å; F392-H394 PolarHBondContact O-N 3.39Å; F392-F395 HydrophobicContact CD2-CD1 4.38Å; F392-F395 HydrophobicContact CE2-CD1 4.44Å; F392-F395 WeakPolarHBondContact O-CB 3.43Å; F392-F395 PolarHBondContact O-N 3.47Å; F392-I396 HydrophobicContact CD2-CG1 4.1Å; F392-I396 HydrophobicContact CE2-CD1 3.74Å; F392-I396 HydrophobicContact CE2-CG1 3.69Å; F392-I396 HydrophobicContact CZ-CD1 4.05Å; F392-I396 HydrophobicContact CZ-CG1 3.91Å; F392-I396 WeakPolarHBondContact O-CG1 3.33Å; F392-I396 PolarHBondContact O-N 3.23Å; F392-F418 HydrophobicContact CB-CD2 3.69Å; F392-F418 HydrophobicContact CB-CE2 3.5Å; F392-F418 HydrophobicContact CB-CG 4.5Å; F392-F418 HydrophobicContact CB-CZ 4.19Å; F392-F418 HydrophobicContact CD2-CD1 4.14Å; F392-F418 HydrophobicContact CD2-CD2 4.06Å; F392-F418 AromaticContact CD2-CE1 3.57Å; F392-F418 HydrophobicContact CD2-CE1 3.57Å; F392-F418 AromaticContact CD2-CE2 3.48Å; F392-F418 HydrophobicContact CD2-CE2 3.48Å; F392-F418 VanDerWaalsContact CD2-CE2 3.48Å; F392-F418 HydrophobicContact CD2-CG 4.37Å; F392-F418 AromaticContact CD2-CZ 3.2Å; F392-F418 HydrophobicContact CD2-CZ 3.2Å; F392-F418 HydrophobicContact CE2-CE1 4.02Å; F392-F418 HydrophobicContact CE2-CE2 4.45Å; F392-F418 AromaticContact CE2-CZ 3.79Å; F392-F418 HydrophobicContact CE2-CZ 3.79Å; F392-F418 HydrophobicContact CG-CD2 4.29Å; F392-F418 AromaticContact CG-CE2 3.72Å; F392-F418 HydrophobicContact CG-CE2 3.72Å; F392-F418 AromaticContact CG-CZ 3.9Å; F392-F418 HydrophobicContact CG-CZ 3.9Å
393	V	98.3	Very high	96.2	Very high	46 Å²	46	56 Å²	56	28%	0.279	31%	0.305	S	S	.	.	H	α-helix	trans	-58.6	-45.3	175	176.4	0	0	0	0	110.8	L383 F388 S389 E390 I396 T397	L383-V393 HydrophobicContact CB-CG2 4.24Å; L383-V393 HydrophobicContact CD1-CG2 4.11Å; F388-V393 HydrophobicContact CB-CG2 3.89Å; S389-V393 WeakPolarHBondContact O-CG2 3.22Å; S389-V393 PolarHBondContact O-N 3.23Å; E390-V393 PolarHBondContact O-N 3.45Å; V393-I396 PolarHBondContact O-N 3.05Å; V393-T397 WeakPolarHBondContact O-CB 3.35Å; V393-T397 PolarHBondContact O-N 2.94Å; V393-T397 PolarHBondContact O-OG1 3.37Å
394	H	97.8	Very high	96.2	Very high	88 Å²	88	56.6 Å²	56.6	41%	0.407	31%	0.31	S	S	.	.	H	α-helix	trans	-62.8	-43.8	176.1	-173.8	-99.5	0	0	0	112.1	E390 F392 I396 T397 Q398 H416	E390-H394 VanDerWaalsContact O-CB 3.32Å; E390-H394 WeakPolarHBondContact O-CB 3.35Å; E390-H394 PolarHBondContact O-N 2.87Å; F392-H394 VanDerWaalsContact C-N 3.31Å; F392-H394 PolarHBondContact O-N 3.39Å; H394-I396 PolarHBondContact O-N 3.02Å; H394-T397 PolarHBondContact O-N 3.23Å; H394-Q398 PolarHBondContact NE2-NE2 3.27Å; H394-Q398 VanDerWaalsContact O-CG 3.28Å; H394-Q398 WeakPolarHBondContact O-CG 2.97Å; H394-Q398 PolarHBondContact O-N 3.43Å; H394-H416 AromaticContact CE1-NE2 3.64Å; H394-H416 AromaticContact CG-NE2 3.86Å; H394-H416 AromaticContact ND1-CD2 3.83Å; H394-H416 AromaticContact ND1-CE1 3.69Å; H394-H416 AromaticContact ND1-NE2 2.83Å; H394-H416 PolarHBondContact ND1-NE2 2.98Å
395	F	98.5	Very high	96.2	Very high	0 Å²	0	64.2 Å²	64.2	0%	0	34%	0.339	C	S	.	.	H	α-helix	trans	-56.4	-50.7	177.1	175.7	-102.4	0	0	0	112.2	V268 L342 P391 F392 T397 Q398 C399 L413 H416 F418 I419	V268-F395 HydrophobicContact CG2-CZ 4.37Å; L342-F395 HydrophobicContact CD2-CZ 3.99Å; P391-F395 WeakPolarHBondContact O-CB 3.44Å; P391-F395 PolarHBondContact O-N 3.25Å; F392-F395 HydrophobicContact CD2-CD1 4.38Å; F392-F395 HydrophobicContact CE2-CD1 4.44Å; F392-F395 WeakPolarHBondContact O-CB 3.43Å; F392-F395 PolarHBondContact O-N 3.47Å; F395-T397 PolarHBondContact O-N 3.42Å; F395-Q398 PolarHBondContact O-N 2.62Å; F395-C399 PolarHBondContact O-N 2.86Å; F395-C399 PolarHBondContact O-SG 2.63Å; F395-L413 HydrophobicContact CD2-CD2 4.12Å; F395-L413 HydrophobicContact CE2-CD1 4.46Å; F395-L413 HydrophobicContact CE2-CD2 3.79Å; F395-H416 VanDerWaalsContact CA-CE1 3.49Å; F395-H416 WeakPolarHBondContact CA-CE1 3.41Å; F395-H416 VanDerWaalsContact CB-CE1 3.45Å; F395-H416 WeakPolarHBondContact CB-CE1 3.46Å; F395-H416 HydrophobicContact CD2-CB 4.48Å; F395-H416 AromaticContact CD2-CG 3.99Å; F395-H416 AromaticContact CD2-ND1 3.81Å; F395-H416 PolarHBondContact N-CE1 2.74Å; F395-F418 HydrophobicContact CB-CB 3.94Å; F395-F418 HydrophobicContact CB-CD1 4.01Å; F395-F418 HydrophobicContact CB-CG 4.13Å; F395-F418 AromaticContact CD1-CD1 3.86Å; F395-F418 HydrophobicContact CD1-CD1 3.86Å; F395-F418 HydrophobicContact CD1-CE1 4.13Å; F395-F418 HydrophobicContact CD2-CD1 4.17Å; F395-F418 HydrophobicContact CE1-CD1 4.38Å; F395-F418 HydrophobicContact CE1-CE1 4.45Å; F395-F418 HydrophobicContact CG-CB 4.38Å; F395-F418 AromaticContact CG-CD1 3.74Å; F395-F418 HydrophobicContact CG-CD1 3.74Å; F395-F418 HydrophobicContact CG-CE1 4.47Å; F395-F418 HydrophobicContact CG-CG 4.35Å; F395-I419 HydrophobicContact CD2-CD1 4.34Å; F395-I419 HydrophobicContact CD2-CG1 4.07Å; F395-I419 HydrophobicContact CE2-CD1 3.67Å; F395-I419 HydrophobicContact CE2-CG1 3.63Å; F395-I419 HydrophobicContact CZ-CD1 3.92Å; F395-I419 HydrophobicContact CZ-CG1 4.39Å
396	I	98.3	Very high	96.5	Very high	4 Å²	4	62.2 Å²	62.2	2%	0.021	32%	0.319	C	S	.	.	H	α-helix	trans	-63.6	-42.9	178.9	-63.6	-60.5	0	0	0	110.9	F346 M347 L383 F392 V393 H394 Q398 C399 M400	F346-I396 HydrophobicContact CB-CD1 3.62Å; M347-I396 HydrophobicContact CB-CG2 4.18Å; M347-I396 HydrophobicContact SD-CG2 4.37Å; L383-I396 HydrophobicContact CD1-CB 4.18Å; L383-I396 HydrophobicContact CD1-CG1 3.9Å; L383-I396 HydrophobicContact CD1-CG2 4.48Å; F392-I396 HydrophobicContact CD2-CG1 4.1Å; F392-I396 HydrophobicContact CE2-CD1 3.74Å; F392-I396 HydrophobicContact CE2-CG1 3.69Å; F392-I396 HydrophobicContact CZ-CD1 4.05Å; F392-I396 HydrophobicContact CZ-CG1 3.91Å; F392-I396 WeakPolarHBondContact O-CG1 3.33Å; F392-I396 PolarHBondContact O-N 3.23Å; V393-I396 PolarHBondContact O-N 3.05Å; H394-I396 PolarHBondContact O-N 3.02Å; I396-Q398 PolarHBondContact O-N 3.16Å; I396-C399 PolarHBondContact O-N 3.44Å; I396-M400 HydrophobicContact CG2-CG 4.45Å; I396-M400 HydrophobicContact CG2-SD 3.72Å; I396-M400 WeakPolarHBondContact O-CB 3.47Å; I396-M400 WeakPolarHBondContact O-CG 3.06Å; I396-M400 PolarHBondContact O-N 3.2Å
397	T	97.3	Very high	96.7	Very high	55 Å²	55	58.7 Å²	58.7	34%	0.337	28%	0.282	S	S	.	.	H	α-helix	trans	-61.5	-42.7	179.9	-57.6	0	0	0	0	111.7	V393 H394 F395 M400 R401	V393-T397 WeakPolarHBondContact O-CB 3.35Å; V393-T397 PolarHBondContact O-N 2.94Å; V393-T397 PolarHBondContact O-OG1 3.37Å; H394-T397 PolarHBondContact O-N 3.23Å; F395-T397 PolarHBondContact O-N 3.42Å; T397-M400 PolarHBondContact O-N 2.92Å; T397-R401 PolarHBondContact O-N 3.31Å
398	Q	97.9	Very high	96.8	Very high	45 Å²	45	54.1 Å²	54.1	21%	0.21	26%	0.262	C	S	.	.	H	α-helix	trans	-65.3	-41.7	175.5	-68.2	-65.3	-26.1	0	0	111.7	H394 F395 I396 M400 P408	H394-Q398 PolarHBondContact NE2-NE2 3.27Å; H394-Q398 VanDerWaalsContact O-CG 3.28Å; H394-Q398 WeakPolarHBondContact O-CG 2.97Å; H394-Q398 PolarHBondContact O-N 3.43Å; F395-Q398 PolarHBondContact O-N 2.62Å; I396-Q398 PolarHBondContact O-N 3.16Å; Q398-M400 PolarHBondContact O-N 3.31Å; Q398-P408 HydrophobicContact CB-CG 4.36Å
399	C	98.2	Very high	96.6	Very high	0 Å²	0	53.5 Å²	53.5	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-64.9	-29.2	177.3	-67	0	0	0	0	112.7	V339 W340 F395 I396 R407	V339-C399 HydrophobicContact CG1-CB 4.04Å; V339-C399 WeakPolarHBondContact O-CB 3.25Å; W340-C399 WeakPolarHBondContact CA-O 3.42Å; F395-C399 PolarHBondContact O-N 2.86Å; F395-C399 PolarHBondContact O-SG 2.63Å; I396-C399 PolarHBondContact O-N 3.44Å; C399-R407 VanDerWaalsContact O-CD 3.25Å; C399-R407 WeakPolarHBondContact O-CD 3.49Å
400	M	96.9	Very high	96.4	Very high	4 Å²	4	51.8 Å²	51.8	2%	0.02	25%	0.25	C	S	.	.	T	Hydrogen-bonded Turn	trans	-107	24.5	-173.1	-64.4	-177.1	51.3	0	0	113.9	W340 G343 I344 M347 S380 P381 I396 T397 Q398 K402	W340-M400 HydrophobicContact CE3-CB 4.47Å; W340-M400 HydrophobicContact CZ3-CB 4.35Å; W340-M400 WeakPolarHBondContact CZ3-O 3.33Å; G343-M400 VanDerWaalsContact C-SD 3.59Å; I344-M400 HydrophobicContact CD1-CE 3.24Å; I344-M400 HydrophobicContact CD1-SD 3.91Å; I344-M400 HydrophobicContact CG1-CE 4.17Å; I344-M400 HydrophobicContact CG1-SD 4.32Å; M347-M400 HydrophobicContact SD-CE 4.32Å; M347-M400 HydrophobicContact SD-SD 4.15Å; S380-M400 WeakPolarHBondContact CB-O 3.44Å; S380-M400 PolarHBondContact OG-O 3.36Å; P381-M400 HydrophobicContact CG-CE 3.61Å; I396-M400 HydrophobicContact CG2-CG 4.45Å; I396-M400 HydrophobicContact CG2-SD 3.72Å; I396-M400 WeakPolarHBondContact O-CB 3.47Å; I396-M400 WeakPolarHBondContact O-CG 3.06Å; I396-M400 PolarHBondContact O-N 3.2Å; T397-M400 PolarHBondContact O-N 2.92Å; Q398-M400 PolarHBondContact O-N 3.31Å; M400-K402 PolarHBondContact O-N 3.45Å
401	R	96.9	Very high	96.3	Very high	100 Å²	100	47.4 Å²	47.4	38%	0.377	23%	0.229	S	C	.	.			trans	-64.7	128.2	167	-65.3	-69.5	-177.9	169.3	-3.3	109.7	T397 Q403 E406 R407	T397-R401 PolarHBondContact O-N 3.31Å; R401-Q403 VanDerWaalsContact C-N 3.35Å; R401-Q403 PolarHBondContact O-N 2.85Å; R401-E406 HydrophobicContact CB-CB 3.88Å; R401-E406 HydrophobicContact CG-CB 4.1Å; R401-R407 HydrophobicContact CB-CG 4.01Å; R401-R407 PolarHBondContact O-NE 3.34Å
402	K	93.1	Very high	96.2	Very high	49 Å²	49	51.3 Å²	51.3	21%	0.213	24%	0.244	C	C	.	.	S	Bend	trans	-55.8	-51.4	179.3	-71.1	-71.1	-170.2	143.5	0	111.1	P325 W340 I375 V376 E378 M400 P404 R407	P325-K402 HydrophobicContact CB-CD 4.45Å; P325-K402 HydrophobicContact CG-CD 3.76Å; W340-K402 HydrophobicContact CH2-CD 3.94Å; W340-K402 HydrophobicContact CZ3-CD 4.07Å; I375-K402 PolarHBondContact O-NZ 3.35Å; V376-K402 PolarHBondContact O-NZ 2.87Å; E378-K402 WeakPolarHBondContact O-CE 3.45Å; E378-K402 PolarHBondContact O-NZ 3.49Å; M400-K402 PolarHBondContact O-N 3.45Å; K402-P404 WeakPolarHBondContact O-CD 3.49Å; K402-R407 PolarHBondContact O-NH2 3.39Å
403	Q	94.3	Very high	96.1	Very high	116 Å²	116	51.4 Å²	51.4	54%	0.542	25%	0.245	S	C	.	.	S	Bend	trans	-68.4	120.1	179.8	-65.6	-61.3	-6.8	0	0	110.7	R401 K405 E406	R401-Q403 VanDerWaalsContact C-N 3.35Å; R401-Q403 PolarHBondContact O-N 2.85Å; Q403-K405 PolarHBondContact O-N 2.9Å; Q403-K405 VanDerWaalsContact O-N 3.14Å; Q403-E406 HydrophobicContact CB-CB 4.34Å; Q403-E406 HydrophobicContact CB-CG 3.93Å; Q403-E406 PolarHBondContact O-N 3.35Å
404	P	93.8	Very high	96.1	Very high	23 Å²	23	51.5 Å²	51.5	15%	0.149	24%	0.243	C	C	.	.	G	3₁₀ helix	trans	-59.1	-31.4	-175.4	-23	30.9	0	0	0	113.9	E326 H336 K402 E406 R407	E326-P404 HydrophobicContact CB-CG 3.73Å; E326-P404 HydrophobicContact CG-CB 4.46Å; E326-P404 HydrophobicContact CG-CG 3.61Å; H336-P404 HydrophobicContact CB-CB 4.22Å; H336-P404 WeakPolarHBondContact CB-O 3.3Å; H336-P404 PolarHBondContact CD2-O 3.1Å; K402-P404 WeakPolarHBondContact O-CD 3.49Å; P404-E406 VanDerWaalsContact C-N 3.29Å; P404-E406 PolarHBondContact O-N 2.91Å; P404-R407 PolarHBondContact O-N 2.89Å
405	K	92.9	Very high	96.1	Very high	203 Å²	203	50 Å²	50	88%	0.883	25%	0.251	S	S	*	.	G	3₁₀ helix	trans	-75.6	-16.1	-179.1	-61.3	178.4	-176	170	0	113.8	Q403	Q403-K405 PolarHBondContact O-N 2.9Å; Q403-K405 VanDerWaalsContact O-N 3.14Å
406	E	95.6	Very high	96.1	Very high	109 Å²	109	50.8 Å²	50.8	51%	0.509	26%	0.255	S	S	.	.	G	3₁₀ helix	trans	-89.1	-12.5	175.4	-65.8	178.1	-166.4	0	0	112	R401 Q403 P404	R401-E406 HydrophobicContact CB-CB 3.88Å; R401-E406 HydrophobicContact CG-CB 4.1Å; Q403-E406 HydrophobicContact CB-CB 4.34Å; Q403-E406 HydrophobicContact CB-CG 3.93Å; Q403-E406 PolarHBondContact O-N 3.35Å; P404-E406 VanDerWaalsContact C-N 3.29Å; P404-E406 PolarHBondContact O-N 2.91Å
407	R	97.4	Very high	96.1	Very high	4 Å²	4	54.6 Å²	54.6	2%	0.015	28%	0.28	C	S	.	.	S	Bend	trans	-77.6	138.2	171.6	-73.7	175	-110.9	157.7	-1.5	109.1	E326 H336 V339 C399 R401 K402 P404	E326-R407 IonicContact OE1-CZ 2.83Å; E326-R407 IonicContact OE1-NH1 3.58Å; E326-R407 PolarHBondContact OE1-NH1 3.43Å; E326-R407 IonicContact OE1-NH2 2.83Å; E326-R407 PolarHBondContact OE1-NH2 3.34Å; E326-R407 VanDerWaalsContact OE1-NH2 3.14Å; E326-R407 IonicContact OE2-CZ 2.72Å; E326-R407 IonicContact OE2-NH1 3.54Å; E326-R407 IonicContact OE2-NH2 2.74Å; E326-R407 PolarHBondContact OE2-NH2 3.19Å; H336-R407 HydrophobicContact CB-CB 4.25Å; H336-R407 PolarHBondContact CD2-O 3.39Å; H336-R407 WeakPolarHBondContact O-CD 3.37Å; H336-R407 PolarHBondContact O-NH1 3.39Å; V339-R407 HydrophobicContact CG1-CB 4.34Å; C399-R407 VanDerWaalsContact O-CD 3.25Å; C399-R407 WeakPolarHBondContact O-CD 3.49Å; R401-R407 HydrophobicContact CB-CG 4.01Å; R401-R407 PolarHBondContact O-NE 3.34Å; K402-R407 PolarHBondContact O-NH2 3.39Å; P404-R407 PolarHBondContact O-N 2.89Å
408	P	96.4	Very high	96.1	Very high	19 Å²	19	52 Å²	52	12%	0.123	26%	0.264	C	S	.	.	P	Polyproline II helix	trans	-68.1	149.7	171.6	28.8	-34.9	0	0	0	111	Q398 E412 L413	Q398-P408 HydrophobicContact CB-CG 4.36Å; P408-E412 WeakPolarHBondContact CA-OE2 3.38Å; P408-E412 HydrophobicContact CB-CB 3.93Å; P408-L413 HydrophobicContact CB-CD2 4.08Å; P408-L413 HydrophobicContact CB-CG 4.15Å; P408-L413 HydrophobicContact CG-CD2 3.3Å; P408-L413 HydrophobicContact CG-CG 3.76Å
409	A	94.1	Very high	96.1	Very high	14 Å²	14	49.9 Å²	49.9	12%	0.116	25%	0.254	C	S	.	.	P	Polyproline II helix	trans	-71.4	159	166.6	0	0	0	0	0	110.8	E411 E412 L413	A409-E411 PolarHBondContact O-N 2.76Å; A409-E412 HydrophobicContact CB-CG 4.42Å; A409-E412 PolarHBondContact N-OE2 3.26Å; A409-E412 WeakPolarHBondContact O-CB 2.99Å; A409-E412 PolarHBondContact O-N 2.92Å; A409-L413 PolarHBondContact O-N 3.27Å
410	P	93.4	Very high	96.1	Very high	0 Å²	0	54 Å²	54	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-54.1	-36.4	178.1	-28.4	36.3	0	0	0	114.2	V268 L271 T272 I335 V339 E412 L413 M414	V268-P410 WeakPolarHBondContact CG1-O 3.4Å; L271-P410 HydrophobicContact CB-CB 4.1Å; L271-P410 HydrophobicContact CB-CG 4.05Å; T272-P410 WeakPolarHBondContact OG1-CB 3.24Å; T272-P410 PolarHBondContact OG1-O 3.46Å; I335-P410 HydrophobicContact CD1-CG 3.88Å; I335-P410 HydrophobicContact CG1-CG 3.47Å; I335-P410 VanDerWaalsContact CG1-CG 3.47Å; V339-P410 HydrophobicContact CG2-CG 4.11Å; P410-E412 VanDerWaalsContact C-N 3.3Å; P410-E412 PolarHBondContact O-N 3.45Å; P410-L413 WeakPolarHBondContact O-CB 3.44Å; P410-L413 PolarHBondContact O-N 2.81Å; P410-M414 PolarHBondContact O-N 2.78Å
411	E	94.3	Very high	96.2	Very high	76 Å²	76	58.9 Å²	58.9	36%	0.355	30%	0.301	S	S	.	.	H	α-helix	trans	-61.8	-37.4	175	-67.6	68.8	-150.1	0	0	112.5	T272 W275 A409 M414	T272-E411 HydrophobicContact CG2-CG 4.13Å; W275-E411 VanDerWaalsContact CD1-OE1 3.24Å; W275-E411 VanDerWaalsContact CD1-OE2 3.27Å; A409-E411 PolarHBondContact O-N 2.76Å; E411-M414 WeakPolarHBondContact O-CB 3.47Å; E411-M414 PolarHBondContact O-N 2.91Å
412	E	96.5	Very high	96.2	Very high	123 Å²	123	54.9 Å²	54.9	58%	0.575	29%	0.287	S	S	*	.	H	α-helix	trans	-74.9	-35.9	179.1	-62.2	170.7	166.3	0	0	110.7	P408 A409 P410 M414 G415	P408-E412 WeakPolarHBondContact CA-OE2 3.38Å; P408-E412 HydrophobicContact CB-CB 3.93Å; A409-E412 HydrophobicContact CB-CG 4.42Å; A409-E412 PolarHBondContact N-OE2 3.26Å; A409-E412 WeakPolarHBondContact O-CB 2.99Å; A409-E412 PolarHBondContact O-N 2.92Å; P410-E412 VanDerWaalsContact C-N 3.3Å; P410-E412 PolarHBondContact O-N 3.45Å; E412-M414 PolarHBondContact O-N 2.77Å; E412-G415 PolarHBondContact O-N 2.85Å
413	L	97.3	Very high	96.4	Very high	2 Å²	2	55.8 Å²	55.8	1%	0.01	29%	0.294	C	S	.	.	H	α-helix	trans	-59.7	-29.7	173.4	-73.8	178.4	0	0	0	112.8	V268 V339 L342 F395 P408 A409 P410 G415 H416 I419	V268-L413 HydrophobicContact CG1-CB 3.82Å; V268-L413 HydrophobicContact CG2-CB 4.42Å; V268-L413 HydrophobicContact CG2-CD1 4.39Å; V339-L413 HydrophobicContact CG1-CD1 3.92Å; V339-L413 HydrophobicContact CG2-CD1 4.09Å; L342-L413 HydrophobicContact CD2-CD1 3.99Å; F395-L413 HydrophobicContact CD2-CD2 4.12Å; F395-L413 HydrophobicContact CE2-CD1 4.46Å; F395-L413 HydrophobicContact CE2-CD2 3.79Å; P408-L413 HydrophobicContact CB-CD2 4.08Å; P408-L413 HydrophobicContact CB-CG 4.15Å; P408-L413 HydrophobicContact CG-CD2 3.3Å; P408-L413 HydrophobicContact CG-CG 3.76Å; A409-L413 PolarHBondContact O-N 3.27Å; P410-L413 WeakPolarHBondContact O-CB 3.44Å; P410-L413 PolarHBondContact O-N 2.81Å; L413-G415 PolarHBondContact O-N 2.85Å; L413-H416 WeakPolarHBondContact O-CB 3.16Å; L413-H416 PolarHBondContact O-N 3.42Å; L413-I419 WeakPolarHBondContact O-CB 3.28Å; L413-I419 WeakPolarHBondContact O-CG1 3.41Å
414	M	97.1	Very high	96.4	Very high	48 Å²	48	53.9 Å²	53.9	24%	0.236	29%	0.288	C	S	.	.	T	Hydrogen-bonded Turn	trans	-61	-25.8	174.6	-71.2	-61.3	-56.2	0	0	113.1	V268 K269 P410 E411 E412 I419	V268-M414 HydrophobicContact CB-SD 4.19Å; V268-M414 HydrophobicContact CG1-CG 3.91Å; V268-M414 HydrophobicContact CG1-SD 3.54Å; V268-M414 VanDerWaalsContact CG1-SD 3.54Å; K269-M414 HydrophobicContact CD-CE 4.44Å; K269-M414 HydrophobicContact CG-CE 3.81Å; K269-M414 HydrophobicContact CG-SD 3.78Å; P410-M414 PolarHBondContact O-N 2.78Å; E411-M414 WeakPolarHBondContact O-CB 3.47Å; E411-M414 PolarHBondContact O-N 2.91Å; E412-M414 PolarHBondContact O-N 2.77Å; M414-I419 HydrophobicContact SD-CG2 4.27Å
415	G	97.1	Very high	96.3	Very high	56 Å²	56	56.2 Å²	56.2	58%	0.577	32%	0.316	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90	-3.5	174.8	0	0	0	0	0	114.4	E412 L413	E412-G415 PolarHBondContact O-N 2.85Å; L413-G415 PolarHBondContact O-N 2.85Å
416	H	98.4	Very high	96.3	Very high	17 Å²	17	49.6 Å²	49.6	8%	0.079	29%	0.29	C	S	.	.	S	Bend	trans	-67.3	137.4	-177.5	-172.7	-81.8	0	0	0	111.3	P391 H394 F395 L413 F418 I419 V420	P391-H416 PolarHBondContact O-CE1 2.92Å; H394-H416 AromaticContact CE1-NE2 3.64Å; H394-H416 AromaticContact CG-NE2 3.86Å; H394-H416 AromaticContact ND1-CD2 3.83Å; H394-H416 AromaticContact ND1-CE1 3.69Å; H394-H416 AromaticContact ND1-NE2 2.83Å; H394-H416 PolarHBondContact ND1-NE2 2.98Å; F395-H416 VanDerWaalsContact CA-CE1 3.49Å; F395-H416 WeakPolarHBondContact CA-CE1 3.41Å; F395-H416 VanDerWaalsContact CB-CE1 3.45Å; F395-H416 WeakPolarHBondContact CB-CE1 3.46Å; F395-H416 HydrophobicContact CD2-CB 4.48Å; F395-H416 AromaticContact CD2-CG 3.99Å; F395-H416 AromaticContact CD2-ND1 3.81Å; F395-H416 PolarHBondContact N-CE1 2.74Å; L413-H416 WeakPolarHBondContact O-CB 3.16Å; L413-H416 PolarHBondContact O-N 3.42Å; H416-F418 VanDerWaalsContact C-N 3.29Å; H416-F418 WeakPolarHBondContact ND1-CB 3.39Å; H416-F418 PolarHBondContact ND1-N 2.79Å; H416-F418 VanDerWaalsContact ND1-N 3.17Å; H416-F418 PolarHBondContact O-N 3.48Å; H416-F418 VanDerWaalsContact O-N 3.13Å; H416-I419 HydrophobicContact CB-CB 4.5Å; H416-I419 HydrophobicContact CB-CG1 4.33Å; H416-I419 PolarHBondContact O-N 2.79Å; H416-V420 PolarHBondContact O-N 3.12Å
417	P	98.2	Very high	96.2	Very high	84 Å²	84	46.5 Å²	46.5	55%	0.545	28%	0.283	S	S	.	.	H	α-helix	trans	-50.9	-42.9	-176.3	-30.7	35.6	0	0	0	114.7	V420 Q421	P417-V420 PolarHBondContact O-N 2.84Å; P417-Q421 VanDerWaalsContact O-CB 3.24Å; P417-Q421 WeakPolarHBondContact O-CB 3.49Å; P417-Q421 PolarHBondContact O-N 3.23Å
418	F	98.4	Very high	96.1	Very high	0 Å²	0	50.2 Å²	50.2	0%	0	31%	0.306	C	S	.	.	H	α-helix	trans	-59.5	-45.1	175	-177.7	-108.4	0	0	0	113.1	E257 G261 A264 P391 F392 F395 H416 F422	E257-F418 HydrophobicContact CG-CE2 4.01Å; E257-F418 HydrophobicContact CG-CZ 4.43Å; G261-F418 VanDerWaalsContact CA-CZ 3.43Å; A264-F418 HydrophobicContact CB-CE1 4.02Å; P391-F418 HydrophobicContact CB-CB 3.98Å; P391-F418 HydrophobicContact CB-CD2 4.36Å; F392-F418 HydrophobicContact CB-CD2 3.69Å; F392-F418 HydrophobicContact CB-CE2 3.5Å; F392-F418 HydrophobicContact CB-CG 4.5Å; F392-F418 HydrophobicContact CB-CZ 4.19Å; F392-F418 HydrophobicContact CD2-CD1 4.14Å; F392-F418 HydrophobicContact CD2-CD2 4.06Å; F392-F418 AromaticContact CD2-CE1 3.57Å; F392-F418 HydrophobicContact CD2-CE1 3.57Å; F392-F418 AromaticContact CD2-CE2 3.48Å; F392-F418 HydrophobicContact CD2-CE2 3.48Å; F392-F418 VanDerWaalsContact CD2-CE2 3.48Å; F392-F418 HydrophobicContact CD2-CG 4.37Å; F392-F418 AromaticContact CD2-CZ 3.2Å; F392-F418 HydrophobicContact CD2-CZ 3.2Å; F392-F418 HydrophobicContact CE2-CE1 4.02Å; F392-F418 HydrophobicContact CE2-CE2 4.45Å; F392-F418 AromaticContact CE2-CZ 3.79Å; F392-F418 HydrophobicContact CE2-CZ 3.79Å; F392-F418 HydrophobicContact CG-CD2 4.29Å; F392-F418 AromaticContact CG-CE2 3.72Å; F392-F418 HydrophobicContact CG-CE2 3.72Å; F392-F418 AromaticContact CG-CZ 3.9Å; F392-F418 HydrophobicContact CG-CZ 3.9Å; F395-F418 HydrophobicContact CB-CB 3.94Å; F395-F418 HydrophobicContact CB-CD1 4.01Å; F395-F418 HydrophobicContact CB-CG 4.13Å; F395-F418 AromaticContact CD1-CD1 3.86Å; F395-F418 HydrophobicContact CD1-CD1 3.86Å; F395-F418 HydrophobicContact CD1-CE1 4.13Å; F395-F418 HydrophobicContact CD2-CD1 4.17Å; F395-F418 HydrophobicContact CE1-CD1 4.38Å; F395-F418 HydrophobicContact CE1-CE1 4.45Å; F395-F418 HydrophobicContact CG-CB 4.38Å; F395-F418 AromaticContact CG-CD1 3.74Å; F395-F418 HydrophobicContact CG-CD1 3.74Å; F395-F418 HydrophobicContact CG-CE1 4.47Å; F395-F418 HydrophobicContact CG-CG 4.35Å; H416-F418 VanDerWaalsContact C-N 3.29Å; H416-F418 WeakPolarHBondContact ND1-CB 3.39Å; H416-F418 PolarHBondContact ND1-N 2.79Å; H416-F418 VanDerWaalsContact ND1-N 3.17Å; H416-F418 PolarHBondContact O-N 3.48Å; H416-F418 VanDerWaalsContact O-N 3.13Å; F418-F422 AromaticContact CD2-CD2 3.93Å; F418-F422 HydrophobicContact CD2-CD2 3.93Å; F418-F422 AromaticContact CD2-CE2 3.7Å; F418-F422 HydrophobicContact CD2-CE2 3.7Å; F418-F422 AromaticContact CE2-CD2 3.72Å; F418-F422 HydrophobicContact CE2-CD2 3.72Å; F418-F422 AromaticContact CE2-CE2 3.36Å; F418-F422 HydrophobicContact CE2-CE2 3.36Å; F418-F422 HydrophobicContact CE2-CZ 4.47Å; F418-F422 HydrophobicContact CG-CD2 4.47Å; F418-F422 HydrophobicContact CZ-CD2 4.09Å; F418-F422 HydrophobicContact CZ-CE2 4.09Å; F418-F422 VanDerWaalsContact O-CD2 3.26Å; F418-F422 WeakPolarHBondContact O-CD2 3.48Å; F418-F422 PolarHBondContact O-N 2.82Å
419	I	98.4	Very high	96.2	Very high	0 Å²	0	50.4 Å²	50.4	0%	0	31%	0.307	C	S	.	.	H	α-helix	trans	-70	-43.8	-179.7	-63.6	-60.5	0	0	0	110.2	A264 V265 V268 F395 L413 M414 H416 Q421 F422 N423	A264-I419 HydrophobicContact CB-CD1 3.74Å; V265-I419 HydrophobicContact CG2-CG2 4Å; V265-I419 WeakPolarHBondContact CG2-O 3.35Å; V268-I419 HydrophobicContact CG2-CD1 4Å; F395-I419 HydrophobicContact CD2-CD1 4.34Å; F395-I419 HydrophobicContact CD2-CG1 4.07Å; F395-I419 HydrophobicContact CE2-CD1 3.67Å; F395-I419 HydrophobicContact CE2-CG1 3.63Å; F395-I419 HydrophobicContact CZ-CD1 3.92Å; F395-I419 HydrophobicContact CZ-CG1 4.39Å; L413-I419 WeakPolarHBondContact O-CB 3.28Å; L413-I419 WeakPolarHBondContact O-CG1 3.41Å; M414-I419 HydrophobicContact SD-CG2 4.27Å; H416-I419 HydrophobicContact CB-CB 4.5Å; H416-I419 HydrophobicContact CB-CG1 4.33Å; H416-I419 PolarHBondContact O-N 2.79Å; I419-Q421 VanDerWaalsContact C-N 3.32Å; I419-Q421 PolarHBondContact O-N 3.46Å; I419-F422 PolarHBondContact O-N 2.93Å; I419-N423 VanDerWaalsContact O-CB 3.28Å; I419-N423 WeakPolarHBondContact O-CB 3.05Å; I419-N423 PolarHBondContact O-N 3.3Å
420	V	98.1	Very high	96.3	Very high	86 Å²	86	49.9 Å²	49.9	52%	0.521	30%	0.302	S	S	.	.	H	α-helix	trans	-59.3	-43.9	176.8	173.3	0	0	0	0	111.1	H416 P417 F422 N423	H416-V420 PolarHBondContact O-N 3.12Å; P417-V420 PolarHBondContact O-N 2.84Å; V420-F422 VanDerWaalsContact C-N 3.28Å; V420-F422 PolarHBondContact O-N 3.17Å; V420-N423 PolarHBondContact O-N 3.09Å
421	Q	97.4	Very high	96.6	Very high	107 Å²	107	51.1 Å²	51.1	50%	0.5	31%	0.311	S	S	.	.	H	α-helix	trans	-57.7	-38.5	178.9	177.5	-179.3	-6.8	0	0	113	P417 I419	P417-Q421 VanDerWaalsContact O-CB 3.24Å; P417-Q421 WeakPolarHBondContact O-CB 3.49Å; P417-Q421 PolarHBondContact O-N 3.23Å; I419-Q421 VanDerWaalsContact C-N 3.32Å; I419-Q421 PolarHBondContact O-N 3.46Å
422	F	97.9	Very high	96.7	Very high	16 Å²	16	52.9 Å²	52.9	7%	0.07	32%	0.321	C	S	.	.	H	α-helix	trans	-101.7	-0.7	-175.9	-68.3	-68.6	0	0	0	114.3	H258 G261 R262 V265 F418 I419 V420 D424	H258-F422 HydrophobicContact CB-CE1 3.95Å; H258-F422 HydrophobicContact CB-CZ 4.42Å; G261-F422 VanDerWaalsContact C-CB 3.43Å; R262-F422 HydrophobicContact CG-CB 4.2Å; R262-F422 HydrophobicContact CG-CD1 4.47Å; V265-F422 HydrophobicContact CG2-CB 4.16Å; F418-F422 AromaticContact CD2-CD2 3.93Å; F418-F422 HydrophobicContact CD2-CD2 3.93Å; F418-F422 AromaticContact CD2-CE2 3.7Å; F418-F422 HydrophobicContact CD2-CE2 3.7Å; F418-F422 AromaticContact CE2-CD2 3.72Å; F418-F422 HydrophobicContact CE2-CD2 3.72Å; F418-F422 AromaticContact CE2-CE2 3.36Å; F418-F422 HydrophobicContact CE2-CE2 3.36Å; F418-F422 HydrophobicContact CE2-CZ 4.47Å; F418-F422 HydrophobicContact CG-CD2 4.47Å; F418-F422 HydrophobicContact CZ-CD2 4.09Å; F418-F422 HydrophobicContact CZ-CE2 4.09Å; F418-F422 VanDerWaalsContact O-CD2 3.26Å; F418-F422 WeakPolarHBondContact O-CD2 3.48Å; F418-F422 PolarHBondContact O-N 2.82Å; I419-F422 PolarHBondContact O-N 2.93Å; V420-F422 VanDerWaalsContact C-N 3.28Å; V420-F422 PolarHBondContact O-N 3.17Å; F422-D424 PolarHBondContact O-N 2.78Å
423	N	97.1	Very high	96.7	Very high	68 Å²	68	49.2 Å²	49.2	36%	0.364	30%	0.301	S	S	.	.			trans	-80.4	55.2	175.2	-172.3	26.2	0	0	0	111.4	V265 K269 I419 V420	V265-N423 HydrophobicContact CG1-CB 4Å; V265-N423 WeakPolarHBondContact CG1-OD1 3.37Å; V265-N423 HydrophobicContact CG2-CB 3.99Å; K269-N423 WeakPolarHBondContact CE-OD1 3.47Å; K269-N423 PolarHBondContact NZ-OD1 2.9Å; I419-N423 VanDerWaalsContact O-CB 3.28Å; I419-N423 WeakPolarHBondContact O-CB 3.05Å; I419-N423 PolarHBondContact O-N 3.3Å; V420-N423 PolarHBondContact O-N 3.09Å
424	D	94.8	Very high	96.7	Very high	77 Å²	77	49.1 Å²	49.1	41%	0.412	30%	0.301	S	S	.	.	S	Bend	trans	-96.4	-2.1	-175.3	69.4	-8.9	0	0	0	113.8	R262 F422 N426	R262-D424 IonicContact CZ-OD1 3.15Å; R262-D424 IonicContact CZ-OD2 3.56Å; R262-D424 VanDerWaalsContact CZ-OD2 3.3Å; R262-D424 IonicContact NE-OD1 2.88Å; R262-D424 PolarHBondContact NE-OD1 3.35Å; R262-D424 VanDerWaalsContact NE-OD1 3.15Å; R262-D424 IonicContact NE-OD2 2.74Å; R262-D424 PolarHBondContact NE-OD2 3.12Å; R262-D424 IonicContact NH2-OD1 3.2Å; R262-D424 IonicContact NH2-OD2 2.7Å; R262-D424 PolarHBondContact NH2-OD2 3Å; F422-D424 PolarHBondContact O-N 2.78Å; D424-N426 VanDerWaalsContact CG-CB 3.49Å; D424-N426 PolarHBondContact O-N 3.21Å; D424-N426 VanDerWaalsContact OD1-CB 3.26Å; D424-N426 WeakPolarHBondContact OD1-CB 3.48Å; D424-N426 PolarHBondContact OD1-N 3.09Å; D424-N426 WeakPolarHBondContact OD2-CB 3.25Å
425	G	91.7	Very high	96.7	Very high	72 Å²	72	48.8 Å²	48.8	74%	0.742	30%	0.303	S	S	*	.			trans	70.7	7.7	-176.9	0	0	0	0	0	114.5	A427	G425-A427 PolarHBondContact O-N 3.32Å
426	N	91.9	Very high	96.6	Very high	64 Å²	64	53.9 Å²	53.9	34%	0.342	31%	0.305	S	S	.	.			trans	-86.4	77.2	-174.1	-168.2	-12.6	0	0	0	112.1	R262 D424 T428 V429	R262-N426 WeakPolarHBondContact CD-O 3.37Å; D424-N426 VanDerWaalsContact CG-CB 3.49Å; D424-N426 PolarHBondContact O-N 3.21Å; D424-N426 VanDerWaalsContact OD1-CB 3.26Å; D424-N426 WeakPolarHBondContact OD1-CB 3.48Å; D424-N426 PolarHBondContact OD1-N 3.09Å; D424-N426 WeakPolarHBondContact OD2-CB 3.25Å; N426-T428 PolarHBondContact O-N 3.04Å; N426-T428 VanDerWaalsContact OD1-CB 3.25Å; N426-T428 WeakPolarHBondContact OD1-CB 3.41Å; N426-T428 PolarHBondContact OD1-N 3.49Å; N426-T428 PolarHBondContact OD1-OG1 2.9Å; N426-V429 PolarHBondContact O-N 3.25Å
427	A	93.5	Very high	96.4	Very high	43 Å²	43	54 Å²	54	36%	0.355	31%	0.309	S	S	.	.	H	α-helix	trans	-62.3	-21.6	175.4	0	0	0	0	0	113	G425 V429 V430 S431	G425-A427 PolarHBondContact O-N 3.32Å; A427-V429 VanDerWaalsContact C-N 3.25Å; A427-V429 PolarHBondContact O-N 2.89Å; A427-V430 PolarHBondContact O-N 3.26Å; A427-V430 VanDerWaalsContact O-N 3.15Å; A427-S431 WeakPolarHBondContact O-CB 3.22Å; A427-S431 PolarHBondContact O-N 2.7Å
428	T	96.7	Very high	96.1	Very high	82 Å²	82	51.5 Å²	51.5	50%	0.503	29%	0.29	S	S	.	.	H	α-helix	trans	-60	-34.5	-179.6	-46.7	0	0	0	0	112.1	N426 S431 M432	N426-T428 PolarHBondContact O-N 3.04Å; N426-T428 VanDerWaalsContact OD1-CB 3.25Å; N426-T428 WeakPolarHBondContact OD1-CB 3.41Å; N426-T428 PolarHBondContact OD1-N 3.49Å; N426-T428 PolarHBondContact OD1-OG1 2.9Å; T428-S431 PolarHBondContact O-N 3.42Å; T428-M432 HydrophobicContact CG2-CE 4.06Å; T428-M432 HydrophobicContact CG2-CG 4.13Å; T428-M432 HydrophobicContact CG2-SD 4.14Å; T428-M432 WeakPolarHBondContact O-CB 3.28Å; T428-M432 VanDerWaalsContact O-CG 3.28Å; T428-M432 WeakPolarHBondContact O-CG 3.45Å; T428-M432 PolarHBondContact O-N 3.08Å
429	V	97.2	Very high	95.9	Very high	23 Å²	23	57.3 Å²	57.3	14%	0.139	32%	0.318	C	S	.	.	H	α-helix	trans	-61.7	-46.9	176.6	172.9	0	0	0	0	111.2	V259 N426 A427 W433	V259-V429 HydrophobicContact CG2-CG1 4.08Å; N426-V429 PolarHBondContact O-N 3.25Å; A427-V429 VanDerWaalsContact C-N 3.25Å; A427-V429 PolarHBondContact O-N 2.89Å; V429-W433 WeakPolarHBondContact O-CB 3.4Å; V429-W433 PolarHBondContact O-N 2.75Å
430	V	97.6	Very high	95.5	Very high	4 Å²	4	61.4 Å²	61.4	2%	0.024	34%	0.337	C	S	.	.	H	α-helix	trans	-66.9	-45	177.3	-178.3	0	0	0	0	109.9	R262 I263 V291 V297 A427 W433 V434	R262-V430 HydrophobicContact CB-CG2 3.77Å; I263-V430 HydrophobicContact CG1-CG1 4.35Å; I263-V430 HydrophobicContact CG1-CG2 4.3Å; V291-V430 HydrophobicContact CG2-CG1 3.7Å; V297-V430 HydrophobicContact CG2-CG1 4.19Å; A427-V430 PolarHBondContact O-N 3.26Å; A427-V430 VanDerWaalsContact O-N 3.15Å; V430-W433 PolarHBondContact O-N 3.49Å; V430-V434 HydrophobicContact CG1-CG2 4.2Å; V430-V434 WeakPolarHBondContact O-CB 3.01Å; V430-V434 VanDerWaalsContact O-CG2 3.26Å; V430-V434 WeakPolarHBondContact O-CG2 3.42Å; V430-V434 PolarHBondContact O-N 3.07Å
431	S	98.1	Very high	94.9	Very high	25 Å²	25	62.2 Å²	62.2	18%	0.175	33%	0.33	C	S	.	.	H	α-helix	trans	-54.1	-55.2	176.9	168.9	0	0	0	0	112.3	T293 A427 T428 W433 V434 C435	T293-S431 WeakPolarHBondContact O-CB 3.4Å; T293-S431 PolarHBondContact O-OG 2.74Å; A427-S431 WeakPolarHBondContact O-CB 3.22Å; A427-S431 PolarHBondContact O-N 2.7Å; T428-S431 PolarHBondContact O-N 3.42Å; S431-W433 VanDerWaalsContact C-N 3.32Å; S431-W433 PolarHBondContact O-N 3.1Å; S431-V434 PolarHBondContact O-N 3.09Å; S431-C435 WeakPolarHBondContact O-CB 3.38Å; S431-C435 PolarHBondContact O-N 2.87Å; S431-C435 PolarHBondContact O-SG 3.28Å
432	M	97.4	Very high	94.3	Very high	114 Å²	114	65.6 Å²	65.6	56%	0.562	34%	0.339	S	S	*	.	H	α-helix	trans	-60.6	-42.7	-179	-71.7	-176.1	-60.2	0	0	111.8	T428 R436	T428-M432 HydrophobicContact CG2-CE 4.06Å; T428-M432 HydrophobicContact CG2-CG 4.13Å; T428-M432 HydrophobicContact CG2-SD 4.14Å; T428-M432 WeakPolarHBondContact O-CB 3.28Å; T428-M432 VanDerWaalsContact O-CG 3.28Å; T428-M432 WeakPolarHBondContact O-CG 3.45Å; T428-M432 PolarHBondContact O-N 3.08Å; M432-R436 WeakPolarHBondContact O-CB 3.47Å; M432-R436 PolarHBondContact O-N 3.42Å
433	W	97	Very high	93.6	Very high	45 Å²	45	69.5 Å²	69.5	17%	0.17	37%	0.368	C	S	.	.	H	α-helix	trans	-64.5	-44.2	178.4	-180	85.2	0	0	0	111.9	Y252 M255 V259 V429 V430 S431 R436 A437	Y252-W433 AromaticContact CD1-CH2 3.32Å; Y252-W433 HydrophobicContact CD1-CH2 3.32Å; Y252-W433 HydrophobicContact CD1-CZ2 4.23Å; Y252-W433 AromaticContact CD1-CZ3 3.57Å; Y252-W433 HydrophobicContact CD1-CZ3 3.57Å; Y252-W433 HydrophobicContact CE1-CH2 4.07Å; Y252-W433 AromaticContact CE1-CZ3 3.83Å; Y252-W433 HydrophobicContact CE1-CZ3 3.83Å; Y252-W433 AromaticContact CG-CH2 3.66Å; Y252-W433 HydrophobicContact CG-CH2 3.66Å; Y252-W433 HydrophobicContact CG-CZ3 4.06Å; M255-W433 HydrophobicContact CB-CH2 4.47Å; M255-W433 HydrophobicContact CB-CZ2 4.15Å; M255-W433 HydrophobicContact CE-CH2 3.71Å; M255-W433 HydrophobicContact CE-CZ3 4.26Å; M255-W433 HydrophobicContact CG-CH2 3.55Å; M255-W433 HydrophobicContact CG-CZ2 3.6Å; M255-W433 HydrophobicContact SD-CH2 3.57Å; M255-W433 VanDerWaalsContact SD-CH2 3.57Å; M255-W433 HydrophobicContact SD-CZ2 4.19Å; M255-W433 HydrophobicContact SD-CZ3 4.06Å; V259-W433 HydrophobicContact CB-CG 4.45Å; V259-W433 HydrophobicContact CG1-CB 4.28Å; V259-W433 HydrophobicContact CG1-CD2 3.91Å; V259-W433 HydrophobicContact CG1-CE3 3.94Å; V259-W433 HydrophobicContact CG1-CG 4.05Å; V259-W433 HydrophobicContact CG2-CB 3.9Å; V259-W433 HydrophobicContact CG2-CD2 4.43Å; V259-W433 HydrophobicContact CG2-CG 3.79Å; V429-W433 WeakPolarHBondContact O-CB 3.4Å; V429-W433 PolarHBondContact O-N 2.75Å; V430-W433 PolarHBondContact O-N 3.49Å; S431-W433 VanDerWaalsContact C-N 3.32Å; S431-W433 PolarHBondContact O-N 3.1Å; W433-R436 PolarHBondContact O-N 3.14Å; W433-A437 WeakPolarHBondContact O-CB 3.49Å; W433-A437 PolarHBondContact O-N 3.18Å
434	V	96.9	Very high	92.7	Very high	0 Å²	0	72.2 Å²	72.2	0%	0	38%	0.379	C	S	.	.	H	α-helix	trans	-61.4	-49.6	176.1	167.7	0	0	0	0	111	V291 T293 V430 S431 R436 A437 L438	V291-V434 HydrophobicContact CB-CG2 4.33Å; V291-V434 HydrophobicContact CG1-CG1 4.36Å; V291-V434 HydrophobicContact CG1-CG2 3.73Å; V291-V434 HydrophobicContact CG2-CG2 3.63Å; T293-V434 HydrophobicContact CG2-CG1 4.46Å; V430-V434 HydrophobicContact CG1-CG2 4.2Å; V430-V434 WeakPolarHBondContact O-CB 3.01Å; V430-V434 VanDerWaalsContact O-CG2 3.26Å; V430-V434 WeakPolarHBondContact O-CG2 3.42Å; V430-V434 PolarHBondContact O-N 3.07Å; S431-V434 PolarHBondContact O-N 3.09Å; V434-R436 VanDerWaalsContact C-N 3.32Å; V434-R436 PolarHBondContact O-N 3.23Å; V434-A437 PolarHBondContact O-N 2.86Å; V434-L438 HydrophobicContact CG1-CD1 3.83Å; V434-L438 HydrophobicContact CG1-CG 4.27Å; V434-L438 VanDerWaalsContact O-CG 3.28Å; V434-L438 WeakPolarHBondContact O-CG 3.18Å; V434-L438 PolarHBondContact O-N 3.12Å
435	C	96.8	Very high	91.4	Very high	41 Å²	41	75.2 Å²	75.2	28%	0.277	39%	0.39	S	S	.	.	H	α-helix	trans	-56.1	-48.1	179.1	-70.7	0	0	0	0	111.3	S431 A437 L438 E439	S431-C435 WeakPolarHBondContact O-CB 3.38Å; S431-C435 PolarHBondContact O-N 2.87Å; S431-C435 PolarHBondContact O-SG 3.28Å; C435-A437 PolarHBondContact O-N 3.45Å; C435-L438 PolarHBondContact O-N 3.44Å; C435-E439 WeakPolarHBondContact O-CG 3.5Å; C435-E439 PolarHBondContact O-N 2.95Å
436	R	95.4	Very high	89.4	Confident	163 Å²	163	73.7 Å²	73.7	62%	0.615	37%	0.374	S	S	*	.	H	α-helix	trans	-60.9	-46.8	177.2	-178.8	178.7	173	165.1	3.9	112.2	M432 W433 V434 L438 E439 E440	M432-R436 WeakPolarHBondContact O-CB 3.47Å; M432-R436 PolarHBondContact O-N 3.42Å; W433-R436 PolarHBondContact O-N 3.14Å; V434-R436 VanDerWaalsContact C-N 3.32Å; V434-R436 PolarHBondContact O-N 3.23Å; R436-L438 VanDerWaalsContact C-N 3.29Å; R436-L438 PolarHBondContact O-N 3.09Å; R436-E439 PolarHBondContact O-N 3.4Å; R436-E440 HydrophobicContact CG-CG 4.48Å; R436-E440 WeakPolarHBondContact CG-OE1 3.26Å; R436-E440 IonicContact CZ-OE1 2.64Å; R436-E440 IonicContact NE-OE1 2.65Å; R436-E440 PolarHBondContact NE-OE1 3.41Å; R436-E440 IonicContact NH2-OE1 3.3Å; R436-E440 WeakPolarHBondContact O-CG 3.45Å; R436-E440 PolarHBondContact O-N 2.93Å
437	A	94	Very high	87.1	Confident	20 Å²	20	76.6 Å²	76.6	17%	0.165	40%	0.397	C	S	.	.	H	α-helix	trans	-62.5	-37	179.5	0	0	0	0	0	112.2	Y252 W433 V434 C435 R441	Y252-A437 HydrophobicContact CD1-CB 3.83Å; Y252-A437 HydrophobicContact CE1-CB 3.75Å; W433-A437 WeakPolarHBondContact O-CB 3.49Å; W433-A437 PolarHBondContact O-N 3.18Å; V434-A437 PolarHBondContact O-N 2.86Å; C435-A437 PolarHBondContact O-N 3.45Å; A437-R441 WeakPolarHBondContact O-CB 3.29Å; A437-R441 PolarHBondContact O-N 3.25Å; A437-R441 VanDerWaalsContact O-N 3.08Å
438	L	92.7	Very high	85.1	Confident	31 Å²	31	84.1 Å²	84.1	16%	0.162	44%	0.442	C	S	.	.	H	α-helix	trans	-68	-40.9	175.3	-68.6	174.3	0	0	0	112.2	T293 V434 C435 R436 R441 R442	T293-L438 HydrophobicContact CG2-CD1 3.88Å; V434-L438 HydrophobicContact CG1-CD1 3.83Å; V434-L438 HydrophobicContact CG1-CG 4.27Å; V434-L438 VanDerWaalsContact O-CG 3.28Å; V434-L438 WeakPolarHBondContact O-CG 3.18Å; V434-L438 PolarHBondContact O-N 3.12Å; C435-L438 PolarHBondContact O-N 3.44Å; R436-L438 VanDerWaalsContact C-N 3.29Å; R436-L438 PolarHBondContact O-N 3.09Å; L438-R441 PolarHBondContact O-N 2.82Å; L438-R442 WeakPolarHBondContact O-CG 3.34Å; L438-R442 PolarHBondContact O-N 3.3Å
439	E	92.3	Very high	84.5	Confident	123 Å²	123	84.3 Å²	84.3	58%	0.575	44%	0.439	S	S	*	.	H	α-helix	trans	-63.2	-44.6	175.3	-74	171.3	-176.9	0	0	112.1	C435 R436 R441 R442 S443	C435-E439 WeakPolarHBondContact O-CG 3.5Å; C435-E439 PolarHBondContact O-N 2.95Å; R436-E439 PolarHBondContact O-N 3.4Å; E439-R441 VanDerWaalsContact C-N 3.29Å; E439-R441 PolarHBondContact O-N 3.05Å; E439-R442 PolarHBondContact O-N 3.06Å; E439-S443 WeakPolarHBondContact O-CB 3.34Å; E439-S443 PolarHBondContact O-N 3.26Å; E439-S443 PolarHBondContact O-OG 3.47Å
440	E	90.2	Very high	83.8	Confident	85 Å²	85	87.5 Å²	87.5	40%	0.397	46%	0.455	S	S	.	.	H	α-helix	trans	-60.8	-39.9	176.1	-73.1	175	-172.4	0	0	111.3	R436 S443 Q444	R436-E440 HydrophobicContact CG-CG 4.48Å; R436-E440 WeakPolarHBondContact CG-OE1 3.26Å; R436-E440 IonicContact CZ-OE1 2.64Å; R436-E440 IonicContact NE-OE1 2.65Å; R436-E440 PolarHBondContact NE-OE1 3.41Å; R436-E440 IonicContact NH2-OE1 3.3Å; R436-E440 WeakPolarHBondContact O-CG 3.45Å; R436-E440 PolarHBondContact O-N 2.93Å; E440-S443 PolarHBondContact O-N 3.39Å; E440-Q444 WeakPolarHBondContact O-CG 3.32Å; E440-Q444 PolarHBondContact O-N 3.48Å; E440-Q444 VanDerWaalsContact O-N 3.1Å; E440-Q444 PolarHBondContact O-NE2 3.39Å
441	R	86.1	Confident	83	Confident	103 Å²	103	92.1 Å²	92.1	39%	0.389	48%	0.478	S	S	.	.	H	α-helix	trans	-66.8	-44	177	-167.6	-174.6	-166.3	124.1	-1.3	112.4	V251 A437 L438 E439 S443 Q444 Q445	V251-R441 VanDerWaalsContact CB-NH1 3.34Å; V251-R441 PolarHBondContact O-NH1 3.42Å; A437-R441 WeakPolarHBondContact O-CB 3.29Å; A437-R441 PolarHBondContact O-N 3.25Å; A437-R441 VanDerWaalsContact O-N 3.08Å; L438-R441 PolarHBondContact O-N 2.82Å; E439-R441 VanDerWaalsContact C-N 3.29Å; E439-R441 PolarHBondContact O-N 3.05Å; R441-S443 VanDerWaalsContact C-N 3.3Å; R441-S443 PolarHBondContact O-N 3.34Å; R441-Q444 PolarHBondContact O-N 2.86Å; R441-Q445 WeakPolarHBondContact O-CG 3.47Å; R441-Q445 PolarHBondContact O-N 3.1Å; R441-Q445 VanDerWaalsContact O-N 3.13Å
442	R	85.2	Confident	82.2	Confident	179 Å²	179	96.1 Å²	96.1	68%	0.675	50%	0.496	S	S	*	.	H	α-helix	trans	-61.3	-41.2	175.9	-72.3	176.4	-171.5	176.5	5.4	111.3	L438 E439 Q444 Q445	L438-R442 WeakPolarHBondContact O-CG 3.34Å; L438-R442 PolarHBondContact O-N 3.3Å; E439-R442 PolarHBondContact O-N 3.06Å; R442-Q444 VanDerWaalsContact C-N 3.29Å; R442-Q444 PolarHBondContact O-N 3.33Å; R442-Q445 PolarHBondContact O-N 3.19Å
443	S	83.8	Confident	81.2	Confident	98 Å²	98	94.9 Å²	94.9	69%	0.685	49%	0.492	S	S	*	.	H	α-helix	trans	-64.7	-33.7	178.3	-55.2	0	0	0	0	112.5	E439 E440 R441	E439-S443 WeakPolarHBondContact O-CB 3.34Å; E439-S443 PolarHBondContact O-N 3.26Å; E439-S443 PolarHBondContact O-OG 3.47Å; E440-S443 PolarHBondContact O-N 3.39Å; R441-S443 VanDerWaalsContact C-N 3.3Å; R441-S443 PolarHBondContact O-N 3.34Å
444	Q	76.9	Confident	80.2	Confident	125 Å²	125	98.3 Å²	98.3	58%	0.584	51%	0.514	S	S	*	.	H	α-helix	trans	-77.7	-23.3	177	-73.6	169.4	45.1	0	0	113.7	E440 R441 R442	E440-Q444 WeakPolarHBondContact O-CG 3.32Å; E440-Q444 PolarHBondContact O-N 3.48Å; E440-Q444 VanDerWaalsContact O-N 3.1Å; E440-Q444 PolarHBondContact O-NE2 3.39Å; R441-Q444 PolarHBondContact O-N 2.86Å; R442-Q444 VanDerWaalsContact C-N 3.29Å; R442-Q444 PolarHBondContact O-N 3.33Å
445	Q	68.3	Low	79	Confident	140 Å²	140	105.3 Å²	105.3	65%	0.654	55%	0.55	S	S	*	*	H	α-helix	trans	-86.3	-6.7	-178.5	-73.1	180	-9.9	0	0	113.7	R441 R442	R441-Q445 WeakPolarHBondContact O-CG 3.47Å; R441-Q445 PolarHBondContact O-N 3.1Å; R441-Q445 VanDerWaalsContact O-N 3.13Å; R442-Q445 PolarHBondContact O-N 3.19Å
446	G	48.7	Very low	77.6	Confident	39 Å²	39	110.2 Å²	110.2	40%	0.402	57%	0.571	S	S	.	*			trans	71.4	163.8	-174.5	0	0	0	0	0	112.6
447	P	44.9	Very low	76.1	Confident	126 Å²	126	105.8 Å²	105.8	82%	0.818	57%	0.568	S	S	*	*			trans	-63.3	146.5	172.5	27.1	-31.5	0	0	0	110.5
448	P	50.3	Low	74.5	Confident	201 Å²	201	113.6 Å²	113.6	100%	1.305	60%	0.604	S	S	*	*			trans	-62.6	0	-178.3	27	-35	0	0	0	113.8

Retrieved 448 of 448 residues in 408.8 ms (Link to these results)

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