A0A096NTW6_PAPAN Loading...

CDK2-associated and cullin domain-containing protein 1

Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition.

AlphaFold DB (A0A2K5XHT7), UniProt , Accession A0A096NTW6, Species PAPAN (Papio anubis, Olive baboon), Gene CACUL1, Length 369 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	35.9	Very low	35.4	Very low	234 Å²	234	163.2 Å²	163.2	100%	1.153	87%	0.867	S	S	*	*				0	72	0	-76.3	169.8	172.4	0	0	104.9
2	E	35.8	Very low	35	Very low	179 Å²	179	157.5 Å²	157.5	84%	0.836	85%	0.85	S	S	*	*				70.3	129.8	54.1	-142.7	172.9	-148.2	0	0	111.7
3	E	34.4	Very low	35	Very low	179 Å²	179	161.6 Å²	161.6	84%	0.836	85%	0.848	S	S	*	*			trans	75.2	139.4	174.2	-58.7	-175.4	146.1	0	0	118.1
4	S	35.8	Very low	35.2	Very low	106 Å²	106	162.9 Å²	162.9	74%	0.741	85%	0.847	S	S	*	*			cis	-169.3	128.6	-16	-90.2	0	0	0	0	104
5	M	35.9	Very low	35.5	Very low	189 Å²	189	157.9 Å²	157.9	93%	0.931	84%	0.839	S	S	*	*			trans	-113.4	100.3	178	-160.5	169.1	-178.5	0	0	106.2	E7	M5-E7 PolarHBondContact O-N 3.42Å
6	E	40.9	Very low	35.9	Very low	189 Å²	189	160 Å²	160	88%	0.883	85%	0.846	S	S	*	*	P	Polyproline II helix	trans	-73.2	116.6	171.8	-70.3	-179.1	164.5	0	0	107.9
7	E	38.9	Very low	36.4	Very low	189 Å²	189	160.6 Å²	160.6	88%	0.883	85%	0.846	S	S	*	*	P	Polyproline II helix	trans	-73.5	122.1	174.2	-71.8	-178.7	151.1	0	0	109.7	M5 E9	M5-E7 PolarHBondContact O-N 3.42Å; E7-E9 PolarHBondContact O-N 3.2Å
8	E	35.1	Very low	36.7	Very low	194 Å²	194	158.6 Å²	158.6	91%	0.907	84%	0.835	S	S	*	*	P	Polyproline II helix	trans	-61.3	119	161.5	-96.1	-175.5	142.1	0	0	109.3	G10	E8-G10 PolarHBondContact O-N 3.37Å
9	E	34.6	Very low	37	Very low	195 Å²	195	158.3 Å²	158.3	91%	0.911	84%	0.835	S	S	*	*			trans	-68.1	112.5	174.8	-157.8	172.4	-164.2	0	0	109.6	E7	E7-E9 PolarHBondContact O-N 3.2Å
10	G	31	Very low	37.1	Very low	67 Å²	67	156.7 Å²	156.7	69%	0.691	82%	0.822	S	S	*	*			trans	-62.9	132.2	179.1	0	0	0	0	0	112.4	E8 S12	E8-G10 PolarHBondContact O-N 3.37Å; G10-S12 PolarHBondContact O-N 3.21Å
11	G	30.7	Very low	37.4	Very low	74 Å²	74	155.5 Å²	155.5	76%	0.763	82%	0.817	S	S	*	*			trans	-57.6	118.5	173.2	0	0	0	0	0	112.2
12	S	31.2	Very low	37.4	Very low	95 Å²	95	151.7 Å²	151.7	66%	0.664	80%	0.796	S	S	*	*			trans	-93.7	114.4	162.8	-171.9	0	0	0	0	109	G10 E14	G10-S12 PolarHBondContact O-N 3.21Å; S12-E14 PolarHBondContact O-N 2.86Å
13	Y	35.4	Very low	37.8	Very low	211 Å²	211	149.7 Å²	149.7	83%	0.827	79%	0.791	S	S	*	*			trans	-64.2	84.1	171	36.8	-86.5	0	0	0	109.8	A15	Y13-A15 PolarHBondContact O-N 2.88Å
14	E	37.7	Very low	38	Very low	179 Å²	179	147 Å²	147	84%	0.836	78%	0.782	S	S	*	*			trans	-75.8	112.6	167.2	-83.7	-175.5	153.1	0	0	110.1	S12 M16	S12-E14 PolarHBondContact O-N 2.86Å; E14-M16 PolarHBondContact O-N 2.99Å
15	A	39.6	Very low	38.6	Very low	88 Å²	88	149.5 Å²	149.5	73%	0.727	78%	0.776	S	S	*	*			trans	-56.3	122.2	175.4	0	0	0	0	0	110.4	Y13 M17	Y13-A15 PolarHBondContact O-N 2.88Å; A15-M17 PolarHBondContact O-N 2.84Å
16	M	41.2	Very low	38.9	Very low	192 Å²	192	148.5 Å²	148.5	95%	0.946	77%	0.768	S	S	*	*			trans	-63.3	94.3	170.1	-61.6	-179.4	-177	0	0	108.9	E14 D18	E14-M16 PolarHBondContact O-N 2.99Å; M16-D18 PolarHBondContact O-N 3.44Å
17	M	45	Very low	38.7	Very low	171 Å²	171	142.9 Å²	142.9	84%	0.842	76%	0.755	S	S	*	*			trans	-73.6	104.3	163.3	-76.9	-87.1	-178.9	0	0	107	A15 D19	A15-M17 PolarHBondContact O-N 2.84Å; M17-D19 VanDerWaalsContact C-N 3.33Å; M17-D19 PolarHBondContact O-N 3.08Å
18	D	40.8	Very low	38.6	Very low	123 Å²	123	138.4 Å²	138.4	66%	0.658	75%	0.75	S	S	*	*			trans	-67.4	89	174.9	-155.9	0.8	0	0	0	108	M16 Q20	M16-D18 PolarHBondContact O-N 3.44Å; D18-Q20 PolarHBondContact O-N 2.99Å; D18-Q20 PolarHBondContact OD1-NE2 3.47Å; D18-Q20 VanDerWaalsContact OD1-NE2 3.14Å; D18-Q20 PolarHBondContact OD2-NE2 3.47Å
19	D	43.3	Very low	39	Very low	154 Å²	154	135 Å²	135	82%	0.824	74%	0.742	S	S	*	*			trans	-75.2	72.2	177.6	-116.7	-0.5	0	0	0	109.2	M17 N21	M17-D19 VanDerWaalsContact C-N 3.33Å; M17-D19 PolarHBondContact O-N 3.08Å; D19-N21 PolarHBondContact O-N 2.96Å
20	Q	38.9	Very low	39.1	Very low	126 Å²	126	132.6 Å²	132.6	59%	0.589	74%	0.735	S	S	*	*			trans	-71.8	72.8	165.6	-86.3	146.2	21	0	0	109.6	D18 H22	D18-Q20 PolarHBondContact O-N 2.99Å; D18-Q20 PolarHBondContact OD1-NE2 3.47Å; D18-Q20 VanDerWaalsContact OD1-NE2 3.14Å; D18-Q20 PolarHBondContact OD2-NE2 3.47Å; Q20-H22 PolarHBondContact O-N 3.03Å
21	N	42.4	Very low	39.1	Very low	131 Å²	131	132.5 Å²	132.5	70%	0.701	74%	0.735	S	S	*	*			trans	-69.1	78.8	157.8	-176.9	21.4	0	0	0	108.5	D19 N23	D19-N21 PolarHBondContact O-N 2.96Å; N21-N23 PolarHBondContact O-N 3.07Å; N21-N23 VanDerWaalsContact O-N 3.11Å
22	H	37.3	Very low	39.2	Very low	154 Å²	154	139 Å²	139	71%	0.713	74%	0.742	S	S	*	*			trans	-63.9	109.6	164.5	-83.3	-71.8	0	0	0	108.3	Q20 N24	Q20-H22 PolarHBondContact O-N 3.03Å; H22-N24 VanDerWaalsContact C-N 3.35Å; H22-N24 PolarHBondContact O-N 2.99Å
23	N	44.4	Very low	39.3	Very low	137 Å²	137	144.5 Å²	144.5	73%	0.733	75%	0.748	S	S	*	*			trans	-51.7	96.2	168.1	-73.7	-50	0	0	0	109.8	N21 W25	N21-N23 PolarHBondContact O-N 3.07Å; N21-N23 VanDerWaalsContact O-N 3.11Å; N23-W25 PolarHBondContact O-N 2.75Å
24	N	37.9	Very low	39.5	Very low	123 Å²	123	142.9 Å²	142.9	66%	0.658	75%	0.748	S	S	*	*			trans	-79.1	72	174.9	-173.7	15.3	0	0	0	109.9	H22 A27	H22-N24 VanDerWaalsContact C-N 3.35Å; H22-N24 PolarHBondContact O-N 2.99Å; N24-A27 VanDerWaalsContact ND2-CB 3.27Å; N24-A27 WeakPolarHBondContact ND2-CB 3.02Å; N24-A27 VanDerWaalsContact OD1-CB 3.26Å; N24-A27 WeakPolarHBondContact OD1-CB 3.4Å; N24-A27 PolarHBondContact OD1-N 2.88Å; N24-A27 VanDerWaalsContact OD1-N 3.11Å
25	W	49	Very low	39.5	Very low	159 Å²	159	140.2 Å²	140.2	60%	0.602	75%	0.747	S	S	*	*			trans	-81.3	-2.8	166.4	-166.6	-98.1	0	0	0	111.7	N23	N23-W25 PolarHBondContact O-N 2.75Å
26	E	42.2	Very low	39.5	Very low	167 Å²	167	143 Å²	143	78%	0.78	75%	0.749	S	S	*	*	S	Bend	trans	-97.2	-17.7	-171.7	-68.8	-171.9	146.7	0	0	115.1	A28	E26-A28 PolarHBondContact O-N 3.34Å
27	A	35.7	Very low	39.8	Very low	72 Å²	72	139.2 Å²	139.2	60%	0.595	74%	0.738	S	S	*	*	T	Hydrogen-bonded Turn	trans	-79.9	0.9	-169.1	0	0	0	0	0	117.3	N24	N24-A27 VanDerWaalsContact ND2-CB 3.27Å; N24-A27 WeakPolarHBondContact ND2-CB 3.02Å; N24-A27 VanDerWaalsContact OD1-CB 3.26Å; N24-A27 WeakPolarHBondContact OD1-CB 3.4Å; N24-A27 PolarHBondContact OD1-N 2.88Å; N24-A27 VanDerWaalsContact OD1-N 3.11Å
28	A	38.3	Very low	40.1	Very low	94 Å²	94	136.6 Å²	136.6	78%	0.777	73%	0.734	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91.6	-1.1	-178.7	0	0	0	0	0	114.7	E26	E26-A28 PolarHBondContact O-N 3.34Å
29	V	43	Very low	40.6	Very low	124 Å²	124	136.3 Å²	136.3	75%	0.752	74%	0.739	S	S	*	*	S	Bend	trans	-93.4	-20	-169.7	179.1	0	0	0	0	114.1
30	D	35.2	Very low	40.9	Very low	143 Å²	143	134.5 Å²	134.5	77%	0.765	74%	0.736	S	S	*	*	G	3₁₀ helix	trans	-93.8	4.7	-174.4	-86.4	-55.6	0	0	0	115.9	F32	D30-F32 PolarHBondContact O-N 3.14Å
31	G	32.4	Very low	41.2	Very low	66 Å²	66	134 Å²	134	68%	0.68	74%	0.743	S	S	*	*	G	3₁₀ helix	trans	-79.5	-7.8	-176.4	0	0	0	0	0	116.7
32	F	33.1	Very low	41	Very low	209 Å²	209	133.7 Å²	133.7	92%	0.917	75%	0.749	S	S	*	*	G	3₁₀ helix	trans	-124.5	49.6	-175.8	-73.4	-81.5	0	0	0	113.2	D30	D30-F32 PolarHBondContact O-N 3.14Å
33	R	33	Very low	41	Very low	211 Å²	211	132.2 Å²	132.2	80%	0.796	76%	0.755	S	S	*	*			trans	-86.5	102.5	156.2	-96.7	-164.2	-172.6	-106.1	4.2	109.7
34	Q	39.7	Very low	40.5	Very low	177 Å²	177	131.2 Å²	131.2	83%	0.827	76%	0.759	S	S	*	*	P	Polyproline II helix	trans	-63.2	143.4	155.2	-76.6	-175.8	-25	0	0	109.4	L36	Q34-L36 PolarHBondContact O-N 3.5Å
35	P	36.4	Very low	40.6	Very low	123 Å²	123	133 Å²	133	80%	0.799	77%	0.767	S	S	*	*	P	Polyproline II helix	trans	-61.9	134.2	171.6	-15.8	28.5	0	0	0	110.3
36	L	40.7	Very low	39.9	Very low	148 Å²	148	131.6 Å²	131.6	78%	0.775	78%	0.779	S	S	*	*	P	Polyproline II helix	trans	-56.2	134.1	172.5	-82.4	150.7	0	0	0	110.5	Q34	Q34-L36 PolarHBondContact O-N 3.5Å
37	P	47.3	Very low	39.3	Very low	111 Å²	111	128.2 Å²	128.2	72%	0.721	78%	0.779	S	S	*	*	P	Polyproline II helix	trans	-67.9	147.1	170.7	26.7	-31	0	0	0	110.8
38	P	51.7	Low	39.5	Very low	117 Å²	117	130.6 Å²	130.6	76%	0.76	79%	0.788	S	S	*	*	P	Polyproline II helix	trans	-66	151.1	-179.6	26.8	-33.5	0	0	0	111.9
39	P	51.1	Low	39.2	Very low	116 Å²	116	130.7 Å²	130.7	75%	0.753	79%	0.789	S	S	*	*	P	Polyproline II helix	trans	-67.1	147	-177.6	27.4	-34	0	0	0	112.2
40	P	48.9	Very low	38.5	Very low	117 Å²	117	137 Å²	137	76%	0.76	80%	0.799	S	S	*	*	P	Polyproline II helix	trans	-70	149.9	176.8	28.6	-33.3	0	0	0	111.9
41	P	45.7	Very low	38.2	Very low	114 Å²	114	138.7 Å²	138.7	74%	0.74	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-68.4	152.6	179.5	28.4	-33.8	0	0	0	112.1	S43	P41-S43 PolarHBondContact O-N 3.1Å
42	P	38.2	Very low	38.7	Very low	126 Å²	126	140.5 Å²	140.5	82%	0.818	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-68.9	127.7	-176.4	26.7	-32.7	0	0	0	111.9	S44	P42-S44 PolarHBondContact O-N 2.97Å
43	S	36.3	Very low	39	Very low	122 Å²	122	136.6 Å²	136.6	85%	0.853	80%	0.798	S	S	*	*	P	Polyproline II helix	trans	-68.3	123	179.1	-55.3	0	0	0	0	112.2	P41	P41-S43 PolarHBondContact O-N 3.1Å
44	S	34.7	Very low	38.8	Very low	117 Å²	117	130.4 Å²	130.4	82%	0.818	80%	0.8	S	S	*	*	P	Polyproline II helix	trans	-67.9	142.9	173.9	-59.1	0	0	0	0	113.1	P42	P42-S44 PolarHBondContact O-N 2.97Å
45	I	40.8	Very low	38.3	Very low	160 Å²	160	125.4 Å²	125.4	82%	0.821	80%	0.796	S	S	*	*			trans	-25.8	137	166.2	-56	162	0	0	0	114.8
46	P	34.3	Very low	37.9	Very low	130 Å²	130	128 Å²	128	84%	0.844	80%	0.798	S	S	*	*			trans	-95.8	134.8	163.8	33	-24.3	0	0	0	112.2
47	A	29.7	Very low	37.4	Very low	95 Å²	95	127.4 Å²	127.4	79%	0.785	79%	0.794	S	S	*	*			trans	-124.4	159.4	165.9	0	0	0	0	0	108.9
48	P	39.9	Very low	36.6	Very low	122 Å²	122	129.5 Å²	129.5	79%	0.792	80%	0.799	S	S	*	*				-111.2	173.1	-124	40.1	-36.7	0	0	0	117.2
49	A	30.6	Very low	35.5	Very low	96 Å²	96	128.5 Å²	128.5	79%	0.793	80%	0.8	S	S	*	*			trans	74.8	116.1	147.9	0	0	0	0	0	120.8
50	R	29.5	Very low	34.3	Very low	256 Å²	256	129.4 Å²	129.4	97%	0.966	80%	0.803	S	S	*	*				-162.3	115.3	128.3	-140.4	170.4	175.4	141.9	-2.9	112.1
51	E	27.3	Very low	34	Very low	180 Å²	180	129.3 Å²	129.3	84%	0.841	80%	0.803	S	S	*	*			trans	-80.8	179.6	166	-113.2	-168	148.1	0	0	111
52	P	42.8	Very low	33.2	Very low	104 Å²	104	127.9 Å²	127.9	68%	0.675	80%	0.801	S	S	*	*			cis	-140	-145.1	-11.3	39.2	-16.1	0	0	0	110.7
53	P	40.8	Very low	32.7	Very low	126 Å²	126	128.9 Å²	128.9	82%	0.818	80%	0.804	S	S	*	*			cis	-130.3	165.1	-23.9	27.6	-6.1	0	0	0	115.7
54	G	28.4	Very low	32.4	Very low	82 Å²	82	127.9 Å²	127.9	85%	0.845	80%	0.797	S	S	*	*			trans	140	109.7	138.8	0	0	0	0	0	117.8
55	G	28.6	Very low	32.2	Very low	72 Å²	72	129.4 Å²	129.4	74%	0.742	80%	0.801	S	S	*	*			trans	115.5	87.7	144.3	0	0	0	0	0	118.4
56	Q	29.4	Very low	31.7	Very low	178 Å²	178	128.4 Å²	128.4	83%	0.832	80%	0.797	S	S	*	*				44.1	121.6	122.6	-78.3	-179.3	31.1	0	0	117.8
57	L	30.2	Very low	31.5	Very low	134 Å²	134	132.7 Å²	132.7	70%	0.702	80%	0.797	S	S	*	*			cis	175.9	141.3	49	-96.8	152.3	0	0	0	110.4
58	L	28.9	Very low	31.4	Very low	156 Å²	156	137 Å²	137	82%	0.817	80%	0.798	S	S	*	*			trans	56.2	115.8	140.1	-65.2	171.3	0	0	0	124.4
59	A	28.8	Very low	30.8	Very low	96 Å²	96	134.3 Å²	134.3	79%	0.793	79%	0.792	S	S	*	*				92.8	117.9	119.3	0	0	0	0	0	121.9
60	V	27.4	Very low	31.3	Very low	134 Å²	134	136.3 Å²	136.3	81%	0.812	80%	0.797	S	S	*	*			trans	-85.5	179.1	163.8	-140.5	0	0	0	0	108.4
61	P	42.3	Very low	31.5	Very low	115 Å²	115	133.9 Å²	133.9	75%	0.747	79%	0.793	S	S	*	*			cis	-146	167.9	11.8	37.6	-13.8	0	0	0	120.7
62	A	29	Very low	31.6	Very low	85 Å²	85	135 Å²	135	70%	0.702	80%	0.799	S	S	*	*			trans	11.9	145.1	141.1	0	0	0	0	0	122.8
63	V	27.6	Very low	30.9	Very low	146 Å²	146	133.3 Å²	133.3	89%	0.885	80%	0.8	S	S	*	*				-150.9	130.1	129.8	176.3	0	0	0	0	110.9
64	S	29.3	Very low	30.5	Very low	101 Å²	101	135.6 Å²	135.6	71%	0.706	81%	0.805	S	S	*	*			trans	-87.7	167	170.3	-39.3	0	0	0	0	111.7
65	V	31.3	Very low	31.2	Very low	149 Å²	149	136.9 Å²	136.9	90%	0.903	80%	0.798	S	S	*	*				179.2	146.5	129.3	164.5	0	0	0	0	111.6
66	D	29.8	Very low	31.5	Very low	139 Å²	139	142.4 Å²	142.4	74%	0.743	81%	0.807	S	S	*	*			trans	-90.9	176.5	-165.2	-165.7	-85.9	0	0	0	115.6
67	R	30	Very low	32	Very low	220 Å²	220	137.1 Å²	137.1	83%	0.83	80%	0.8	S	S	*	*			trans	106.6	143.9	156.3	-71	-172.3	165.2	173.1	-2.1	117.7
68	K	28.1	Very low	32.7	Very low	186 Å²	186	136.8 Å²	136.8	81%	0.809	81%	0.806	S	S	*	*			cis	-178	143.6	-10.4	177.9	176.5	-178.7	-176.1	0	105.9
69	G	27.5	Very low	33.7	Very low	65 Å²	65	135.1 Å²	135.1	67%	0.67	80%	0.804	S	S	*	*			trans	-72.1	-174.4	179.7	0	0	0	0	0	115.9
70	P	40.1	Very low	34.5	Very low	138 Å²	138	135.9 Å²	135.9	90%	0.896	80%	0.802	S	S	*	*				-145.1	163.9	103.5	32.8	-14.1	0	0	0	116.9
71	K	35.1	Very low	35.3	Very low	205 Å²	205	135 Å²	135	89%	0.891	80%	0.798	S	S	*	*			trans	-88.3	153.5	172.8	-77.2	177.1	169	177.8	0	111.6
72	E	28.8	Very low	35.4	Very low	204 Å²	204	135.7 Å²	135.7	95%	0.953	80%	0.803	S	S	*	*			trans	-161.8	147.6	141.5	-108.2	172.1	-173.7	0	0	109.5
73	G	28	Very low	35.5	Very low	68 Å²	68	140.4 Å²	140.4	70%	0.701	81%	0.811	S	S	*	*			trans	-136	171.6	-176.5	0	0	0	0	0	112.8
74	L	32.6	Very low	36.2	Very low	175 Å²	175	138 Å²	138	92%	0.916	81%	0.806	S	S	*	*			trans	171.1	160.5	144.6	-91.2	169	0	0	0	109.7
75	P	42.3	Very low	36.4	Very low	109 Å²	109	140.6 Å²	140.6	71%	0.708	81%	0.812	S	S	*	*			trans	-98.2	154.7	-153.4	38.6	-34.4	0	0	0	113.3
76	M	35.9	Very low	36.6	Very low	187 Å²	187	137.2 Å²	137.2	92%	0.921	81%	0.807	S	S	*	*			trans	-131	123.2	167.6	-74.4	-69.7	-78.3	0	0	109
77	G	38.3	Very low	36.7	Very low	68 Å²	68	136.4 Å²	136.4	70%	0.701	81%	0.807	S	S	*	*			trans	-70.9	179.7	179	0	0	0	0	0	113.7
78	P	46.6	Very low	37	Very low	127 Å²	127	133.6 Å²	133.6	83%	0.825	81%	0.806	S	S	*	*	P	Polyproline II helix	trans	-71.6	146.9	-173.4	29.1	-32.9	0	0	0	112.3
79	P	48.5	Very low	37.2	Very low	120 Å²	120	133 Å²	133	78%	0.779	81%	0.809	S	S	*	*	P	Polyproline II helix	trans	-78.4	155.2	177.4	32.6	-32.6	0	0	0	111.9
80	P	46.8	Very low	37.5	Very low	113 Å²	113	138.4 Å²	138.4	73%	0.734	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-77.2	161.2	-179.4	33	-34.1	0	0	0	112.2
81	P	42.9	Very low	37.2	Very low	114 Å²	114	140.2 Å²	140.2	74%	0.74	82%	0.82	S	S	*	*	P	Polyproline II helix	trans	-70.7	151.1	177.1	30.3	-33.5	0	0	0	111.6
82	P	45.4	Very low	37.2	Very low	131 Å²	131	140.1 Å²	140.1	85%	0.851	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-80.5	126.8	179.8	30.2	-30.5	0	0	0	111.6
83	E	31.6	Very low	37.2	Very low	184 Å²	184	136 Å²	136	86%	0.86	81%	0.813	S	S	*	*	P	Polyproline II helix	trans	-67.7	141.1	168.8	-70.6	-178.2	141.4	0	0	111.2	N85	E83-N85 PolarHBondContact O-N 3.41Å
84	A	42.2	Very low	37.3	Very low	95 Å²	95	138.6 Å²	138.6	79%	0.785	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-66.7	120	176	0	0	0	0	0	110.8
85	N	33.5	Very low	37.1	Very low	156 Å²	156	138.3 Å²	138.3	83%	0.834	82%	0.819	S	S	*	*			trans	-141.3	98.8	157.3	-92.1	-32.5	0	0	0	109.1	E83	E83-N85 PolarHBondContact O-N 3.41Å
86	G	35.2	Very low	36.5	Very low	77 Å²	77	137.8 Å²	137.8	79%	0.794	82%	0.824	S	S	*	*			trans	-72.6	130.8	168.6	0	0	0	0	0	110.3
87	V	31	Very low	36.1	Very low	123 Å²	123	134.1 Å²	134.1	75%	0.745	82%	0.823	S	S	*	*			trans	-134.4	106	159	-175.8	0	0	0	0	107.6	M89	V87-M89 PolarHBondContact O-N 3.26Å
88	I	36	Very low	35.7	Very low	160 Å²	160	135.7 Å²	135.7	82%	0.821	83%	0.829	S	S	*	*			trans	-67.5	115.4	169.4	-64.2	179.2	0	0	0	107.6
89	M	33.4	Very low	34.9	Very low	174 Å²	174	134.8 Å²	134.8	86%	0.857	83%	0.832	S	S	*	*			trans	-97.5	107.5	166.9	-79.7	-84.3	-138.5	0	0	108.8	V87	V87-M89 PolarHBondContact O-N 3.26Å
90	M	32.9	Very low	34.1	Very low	178 Å²	178	136 Å²	136	88%	0.877	84%	0.837	S	S	*	*			trans	-61.9	131.7	170.7	-80	-172.5	169.7	0	0	111.2
91	L	35.3	Very low	33.3	Very low	177 Å²	177	135 Å²	135	93%	0.927	84%	0.839	S	S	*	*			trans	-59.8	133.4	161.8	-99.5	83.7	0	0	0	110
92	K	33.7	Very low	32.7	Very low	202 Å²	202	139.5 Å²	139.5	88%	0.878	85%	0.847	S	S	*	*			trans	-119.7	114.5	164.6	-154.6	154.4	-177.2	174.4	0	109.6
93	S	29.4	Very low	31.9	Very low	117 Å²	117	137.6 Å²	137.6	82%	0.818	84%	0.842	S	S	*	*			trans	-67.5	143.7	176	-158.7	0	0	0	0	110.8
94	C	29.6	Very low	31.8	Very low	123 Å²	123	133.4 Å²	133.4	83%	0.831	84%	0.838	S	S	*	*			trans	-97.1	129.8	175.3	-68.3	0	0	0	0	110
95	D	27.8	Very low	31.8	Very low	170 Å²	170	134.6 Å²	134.6	91%	0.909	84%	0.838	S	S	*	*			trans	-123.4	140.7	162.8	-113.3	-33	0	0	0	109.9
96	A	30.1	Very low	31.8	Very low	98 Å²	98	131.7 Å²	131.7	81%	0.81	84%	0.836	S	S	*	*			trans	-96.3	139.9	-173.9	0	0	0	0	0	111.9
97	A	28.8	Very low	32.2	Very low	109 Å²	109	133.2 Å²	133.2	90%	0.901	83%	0.832	S	S	*	*			trans	-156.5	134.1	154.1	0	0	0	0	0	111
98	A	29.4	Very low	32.2	Very low	101 Å²	101	134.2 Å²	134.2	84%	0.835	84%	0.838	S	S	*	*			trans	-90.8	147.8	-177.7	0	0	0	0	0	112.7
99	A	30.5	Very low	32.1	Very low	108 Å²	108	131 Å²	131	89%	0.893	84%	0.835	S	S	*	*			trans	-160.4	144	149.7	0	0	0	0	0	111.3
100	V	30.8	Very low	32.1	Very low	146 Å²	146	128.4 Å²	128.4	89%	0.885	83%	0.834	S	S	*	*			trans	-106.3	140.6	-167.7	170	0	0	0	0	110.8
101	A	30	Very low	32.4	Very low	92 Å²	92	124.9 Å²	124.9	76%	0.76	83%	0.828	S	S	*	*			trans	167.1	115.1	130.5	0	0	0	0	0	116.6
102	K	29.7	Very low	32.6	Very low	209 Å²	209	122.4 Å²	122.4	91%	0.909	82%	0.82	S	S	*	*				75.6	111.6	122.8	-136.1	173	-177.4	179.3	0	124.5
103	A	28.2	Very low	33.3	Very low	91 Å²	91	119.2 Å²	119.2	75%	0.752	81%	0.811	S	S	*	*			trans	80.5	98.8	132.7	0	0	0	0	0	125.6
104	A	29.9	Very low	34.1	Very low	95 Å²	95	119.3 Å²	119.3	79%	0.785	80%	0.802	S	S	*	*				23.1	163.5	126.3	0	0	0	0	0	125.3
105	P	43.3	Very low	35.2	Very low	121 Å²	121	119.2 Å²	119.2	79%	0.786	79%	0.792	S	S	*	*			cis	-142.1	166.9	-28.5	36.1	-15.7	0	0	0	119
106	A	32.2	Very low	36.3	Very low	94 Å²	94	117.1 Å²	117.1	78%	0.777	78%	0.781	S	S	*	*			trans	74.7	160	144.9	0	0	0	0	0	123.1
107	P	44.8	Very low	37	Very low	109 Å²	109	117 Å²	117	71%	0.708	77%	0.77	S	S	*	*			cis	-132.3	165.7	-40	35.6	-18.7	0	0	0	113.4
108	T	30.3	Very low	37.8	Very low	144 Å²	144	116.4 Å²	116.4	88%	0.883	76%	0.76	S	S	*	*			trans	160.1	148.1	131.2	41	0	0	0	0	114.3
109	A	33.9	Very low	38.5	Very low	92 Å²	92	115.5 Å²	115.5	76%	0.76	74%	0.744	S	S	*	*			trans	75	79.8	166.7	0	0	0	0	0	118.8	S111	A109-S111 PolarHBondContact O-N 3.41Å
110	S	33.5	Very low	39.2	Very low	120 Å²	120	113.6 Å²	113.6	84%	0.839	72%	0.724	S	S	*	*			trans	-70	102.8	156.8	-64.9	0	0	0	0	110.5
111	S	40.2	Very low	39.8	Very low	105 Å²	105	114.8 Å²	114.8	73%	0.734	72%	0.718	S	S	*	*			trans	-93.6	87.5	156.7	-61	0	0	0	0	108	A109 I113	A109-S111 PolarHBondContact O-N 3.41Å; S111-I113 VanDerWaalsContact C-N 3.35Å; S111-I113 PolarHBondContact O-N 3.14Å
112	T	39.3	Very low	40.6	Very low	124 Å²	124	119.3 Å²	119.3	76%	0.761	72%	0.72	S	S	*	*			trans	-74.1	90.5	172.6	-50.3	0	0	0	0	108.5	N114	T112-N114 PolarHBondContact O-N 3.06Å
113	I	47	Very low	41.6	Very low	135 Å²	135	115.1 Å²	115.1	69%	0.692	71%	0.707	S	S	*	*			trans	-72.1	105.6	162.9	-56.9	178	0	0	0	106.1	S111 I115	S111-I113 VanDerWaalsContact C-N 3.35Å; S111-I113 PolarHBondContact O-N 3.14Å; I113-I115 HydrophobicContact CB-CG1 4.4Å; I113-I115 HydrophobicContact CG2-CD1 4.16Å; I113-I115 HydrophobicContact CG2-CG1 3.68Å; I113-I115 PolarHBondContact O-N 2.92Å
114	N	46.8	Very low	42.6	Very low	120 Å²	120	118.4 Å²	118.4	64%	0.642	71%	0.709	S	S	*	*			trans	-71.4	92.6	173.8	-178.1	9.2	0	0	0	109.5	T112 N116	T112-N114 PolarHBondContact O-N 3.06Å; N114-N116 VanDerWaalsContact C-N 3.31Å; N114-N116 PolarHBondContact OD1-N 3.26Å
115	I	52.8	Low	44.1	Very low	120 Å²	120	120.1 Å²	120.1	62%	0.615	71%	0.705	S	S	*	*			trans	-86	-1.3	177.6	-59.4	175.8	0	0	0	111.8	I113 T117	I113-I115 HydrophobicContact CB-CG1 4.4Å; I113-I115 HydrophobicContact CG2-CD1 4.16Å; I113-I115 HydrophobicContact CG2-CG1 3.68Å; I113-I115 PolarHBondContact O-N 2.92Å; I115-T117 PolarHBondContact O-N 3.3Å
116	N	50.7	Low	45.7	Very low	126 Å²	126	118.3 Å²	118.3	67%	0.674	69%	0.691	S	S	*	*			trans	-108.3	45.6	-162.8	-62.1	-19	0	0	0	114.4	N114	N114-N116 VanDerWaalsContact C-N 3.31Å; N114-N116 PolarHBondContact OD1-N 3.26Å
117	T	44.5	Very low	48.2	Very low	95 Å²	95	114.3 Å²	114.3	58%	0.583	66%	0.657	S	S	*	*	S	Bend	trans	-135.1	-13.2	172.5	-59.2	0	0	0	0	114.9	I115	I115-T117 PolarHBondContact O-N 3.3Å
118	S	46.4	Very low	50.4	Low	98 Å²	98	112.3 Å²	112.3	69%	0.685	64%	0.643	S	S	*	*	S	Bend	trans	-102	-19.9	175.6	-90.5	0	0	0	0	115.4
119	T	44	Very low	53.2	Low	81 Å²	81	110.6 Å²	110.6	50%	0.497	63%	0.627	S	S	.	*	S	Bend	trans	-80.7	-20.1	177.6	43	0	0	0	0	113.1	K121 F122	T119-K121 PolarHBondContact O-N 3.16Å; T119-F122 PolarHBondContact O-N 3.25Å
120	S	45.4	Very low	56	Low	69 Å²	69	112.4 Å²	112.4	48%	0.483	62%	0.62	S	S	.	*	T	Hydrogen-bonded Turn	trans	-76.6	-18.4	-176.6	-162.6	0	0	0	0	114.5
121	K	44.1	Very low	58.7	Low	171 Å²	171	109.7 Å²	109.7	74%	0.743	60%	0.596	S	S	*	*	T	Hydrogen-bonded Turn	trans	-80.5	-20	176.8	-62.4	-176.8	-174.8	176.5	0	112.9	T119	T119-K121 PolarHBondContact O-N 3.16Å
122	F	46.8	Very low	61.3	Low	186 Å²	186	104.7 Å²	104.7	82%	0.816	56%	0.561	S	S	*	*	T	Hydrogen-bonded Turn	trans	-86.5	-16.6	175.8	-77.9	-83.4	0	0	0	113.3	T119	T119-F122 PolarHBondContact O-N 3.25Å
123	L	49.7	Very low	64	Low	122 Å²	122	104.1 Å²	104.1	64%	0.639	55%	0.548	S	S	*	.	S	Bend	trans	-92.6	-4.7	-177	-66.1	172.8	0	0	0	114.3
124	M	49.9	Very low	66.2	Low	160 Å²	160	100.8 Å²	100.8	79%	0.788	54%	0.537	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.9	-2.7	-176.1	-90	-175.2	167.1	0	0	115.3
125	N	60.8	Low	68.4	Low	131 Å²	131	98 Å²	98	70%	0.701	52%	0.524	S	S	*	.	T	Hydrogen-bonded Turn	trans	-109.2	22	176.1	-76.5	-31.2	0	0	0	112.6	I127 Q173	N125-I127 PolarHBondContact O-N 3.17Å; N125-Q173 PolarHBondContact O-NE2 3.23Å; N125-Q173 PolarHBondContact O-OE1 3.47Å
126	V	76.9	Confident	70.4	Confident	82 Å²	82	94.9 Å²	94.9	50%	0.497	51%	0.505	S	S	.	.			trans	-70.8	112.7	170.2	178.1	0	0	0	0	107.4	T128	V126-T128 PolarHBondContact O-N 3.2Å; V126-T128 VanDerWaalsContact O-N 3.13Å
127	I	85.1	Confident	72.6	Confident	11 Å²	11	90.7 Å²	90.7	6%	0.056	48%	0.48	C	S	.	.			trans	-66.4	113.7	170.6	-68.3	173.2	0	0	0	106.2	N125 D131 Y136 K169 Q173 H175	N125-I127 PolarHBondContact O-N 3.17Å; I127-D131 HydrophobicContact CG2-CB 4.06Å; I127-Y136 HydrophobicContact CD1-CD1 4.29Å; I127-Y136 HydrophobicContact CD1-CD2 4.27Å; I127-Y136 HydrophobicContact CD1-CE1 3.78Å; I127-Y136 HydrophobicContact CD1-CE2 3.75Å; I127-Y136 VanDerWaalsContact CD1-CZ 3.48Å; I127-Y136 HydrophobicContact CG1-CE2 3.83Å; I127-Y136 HydrophobicContact CG2-CD2 4.02Å; I127-Y136 HydrophobicContact CG2-CE2 3.97Å; I127-K169 HydrophobicContact CD1-CB 4.2Å; I127-Q173 HydrophobicContact CB-CB 3.92Å; I127-Q173 HydrophobicContact CB-CG 4.03Å; I127-Q173 HydrophobicContact CD1-CB 4.17Å; I127-Q173 HydrophobicContact CD1-CG 3.79Å; I127-Q173 HydrophobicContact CG1-CB 4.24Å; I127-Q173 HydrophobicContact CG1-CG 3.83Å; I127-H175 PolarHBondContact O-NE2 3.14Å
128	T	90.3	Very high	75	Confident	67 Å²	67	89.1 Å²	89.1	41%	0.411	47%	0.471	S	S	.	.			trans	-71.4	160.9	173.6	68.9	0	0	0	0	109.8	V126 E130 D131 Y132	V126-T128 PolarHBondContact O-N 3.2Å; V126-T128 VanDerWaalsContact O-N 3.13Å; T128-E130 PolarHBondContact O-N 3.42Å; T128-D131 WeakPolarHBondContact CB-OD2 3.4Å; T128-D131 PolarHBondContact N-OD2 2.95Å; T128-D131 VanDerWaalsContact N-OD2 3.11Å; T128-D131 PolarHBondContact O-N 2.92Å; T128-D131 PolarHBondContact OG1-N 3.43Å; T128-D131 VanDerWaalsContact OG1-N 3.09Å; T128-D131 PolarHBondContact OG1-OD2 3.05Å; T128-Y132 PolarHBondContact O-N 3.42Å
129	I	89.5	Confident	77.4	Confident	107 Å²	107	90.3 Å²	90.3	55%	0.549	46%	0.464	S	S	.	.	H	α-helix	trans	-57.4	-34	173.8	-63.7	168.1	0	0	0	110.5	K133	I129-K133 HydrophobicContact CG2-CD 4.33Å; I129-K133 WeakPolarHBondContact O-CG 3.34Å; I129-K133 PolarHBondContact O-N 3.3Å; I129-K133 VanDerWaalsContact O-N 3.07Å
130	E	91.8	Very high	79.9	Confident	130 Å²	130	86.5 Å²	86.5	61%	0.607	44%	0.441	S	S	*	.	H	α-helix	trans	-69.4	-43.4	177.8	-164.3	61.8	-144.8	0	0	111.6	T128 Y132 K133 S134	T128-E130 PolarHBondContact O-N 3.42Å; E130-Y132 VanDerWaalsContact C-N 3.32Å; E130-Y132 PolarHBondContact O-N 3.47Å; E130-K133 PolarHBondContact O-N 2.98Å; E130-S134 VanDerWaalsContact O-CB 3.3Å; E130-S134 WeakPolarHBondContact O-CB 3.47Å; E130-S134 PolarHBondContact O-N 2.94Å; E130-S134 PolarHBondContact O-OG 2.9Å
131	D	91.8	Very high	82.3	Confident	64 Å²	64	85.4 Å²	85.4	34%	0.342	43%	0.429	S	S	.	.	H	α-helix	trans	-62	-43.3	175.3	-61.9	-44.9	0	0	0	110.9	I127 T128 K133 S134 T135 Y136	I127-D131 HydrophobicContact CG2-CB 4.06Å; T128-D131 WeakPolarHBondContact CB-OD2 3.4Å; T128-D131 PolarHBondContact N-OD2 2.95Å; T128-D131 VanDerWaalsContact N-OD2 3.11Å; T128-D131 PolarHBondContact O-N 2.92Å; T128-D131 PolarHBondContact OG1-N 3.43Å; T128-D131 VanDerWaalsContact OG1-N 3.09Å; T128-D131 PolarHBondContact OG1-OD2 3.05Å; D131-K133 VanDerWaalsContact C-N 3.35Å; D131-K133 PolarHBondContact O-N 3.42Å; D131-S134 PolarHBondContact O-N 2.97Å; D131-T135 WeakPolarHBondContact O-CA 3.28Å; D131-T135 VanDerWaalsContact O-CB 3.24Å; D131-T135 WeakPolarHBondContact O-CB 3.34Å; D131-T135 PolarHBondContact O-N 3.16Å; D131-Y136 HydrophobicContact CB-CD2 4.48Å; D131-Y136 HydrophobicContact CB-CE2 4.31Å; D131-Y136 WeakPolarHBondContact O-CD2 3.31Å; D131-Y136 PolarHBondContact O-N 3.47Å
132	Y	94.8	Very high	84.7	Confident	0 Å²	0	78.6 Å²	78.6	0%	0	41%	0.408	C	S	.	.	I	π-helix	trans	-54.1	-52.3	174.5	167.3	-96.4	0	0	0	110.5	T128 E130 Y136 W137 H175 Q178 M179 D182	T128-Y132 PolarHBondContact O-N 3.42Å; E130-Y132 VanDerWaalsContact C-N 3.32Å; E130-Y132 PolarHBondContact O-N 3.47Å; Y132-Y136 PolarHBondContact O-N 3.21Å; Y132-W137 HydrophobicContact CE1-CB 4.15Å; Y132-W137 HydrophobicContact CE2-CB 4.25Å; Y132-W137 HydrophobicContact CE2-CE3 4.49Å; Y132-W137 WeakPolarHBondContact O-CB 3.5Å; Y132-W137 PolarHBondContact O-N 3.31Å; Y132-H175 HydrophobicContact CD2-CB 4.09Å; Y132-H175 HydrophobicContact CE2-CB 4.43Å; Y132-Q178 HydrophobicContact CD1-CG 4.12Å; Y132-Q178 HydrophobicContact CE1-CB 4.47Å; Y132-Q178 HydrophobicContact CE1-CG 3.47Å; Y132-Q178 VanDerWaalsContact CE1-CG 3.47Å; Y132-M179 HydrophobicContact CE2-CB 4.31Å; Y132-M179 VanDerWaalsContact OH-CA 3.28Å; Y132-M179 WeakPolarHBondContact OH-CA 3.42Å; Y132-D182 VanDerWaalsContact CE1-OD2 3.28Å; Y132-D182 WeakPolarHBondContact CE1-OD2 3.39Å; Y132-D182 PolarHBondContact OH-OD2 3.41Å
133	K	94.1	Very high	87.1	Confident	111 Å²	111	70 Å²	70	48%	0.483	37%	0.371	S	S	.	.	I	π-helix	trans	-68.6	-38	-177.3	-72.7	179.9	179.4	178.8	0	114.1	I129 E130 D131 P138	I129-K133 HydrophobicContact CG2-CD 4.33Å; I129-K133 WeakPolarHBondContact O-CG 3.34Å; I129-K133 PolarHBondContact O-N 3.3Å; I129-K133 VanDerWaalsContact O-N 3.07Å; E130-K133 PolarHBondContact O-N 2.98Å; D131-K133 VanDerWaalsContact C-N 3.35Å; D131-K133 PolarHBondContact O-N 3.42Å; K133-P138 VanDerWaalsContact O-CD 3.27Å; K133-P138 WeakPolarHBondContact O-CD 3.37Å; K133-P138 WeakPolarHBondContact O-CG 3.49Å
134	S	93.8	Very high	89.3	Confident	66 Å²	66	64.3 Å²	64.3	46%	0.462	34%	0.341	S	S	.	.	I	π-helix	trans	-90.8	-27.1	-172.3	61.8	0	0	0	0	113.7	E130 D131	E130-S134 VanDerWaalsContact O-CB 3.3Å; E130-S134 WeakPolarHBondContact O-CB 3.47Å; E130-S134 PolarHBondContact O-N 2.94Å; E130-S134 PolarHBondContact O-OG 2.9Å; D131-S134 PolarHBondContact O-N 2.97Å
135	T	93.1	Very high	91.4	Very high	62 Å²	62	59.3 Å²	59.3	38%	0.38	32%	0.318	S	S	.	.	I	π-helix	trans	-122.8	-42	-167.5	-56.9	0	0	0	0	113.5	D131 K139	D131-T135 WeakPolarHBondContact O-CA 3.28Å; D131-T135 VanDerWaalsContact O-CB 3.24Å; D131-T135 WeakPolarHBondContact O-CB 3.34Å; D131-T135 PolarHBondContact O-N 3.16Å; T135-K139 WeakPolarHBondContact O-CD 3.48Å; T135-K139 VanDerWaalsContact O-CE 3.31Å; T135-K139 WeakPolarHBondContact O-CE 3.4Å; T135-K139 WeakPolarHBondContact O-CG 3.47Å
136	Y	94.5	Very high	93	Very high	54 Å²	54	56.8 Å²	56.8	21%	0.212	30%	0.302	C	S	.	.	I	π-helix	trans	-92.6	-53.5	-173.9	-67.9	-93.7	0	0	0	112.1	I127 D131 Y132 K139 L140 K169 C170	I127-Y136 HydrophobicContact CD1-CD1 4.29Å; I127-Y136 HydrophobicContact CD1-CD2 4.27Å; I127-Y136 HydrophobicContact CD1-CE1 3.78Å; I127-Y136 HydrophobicContact CD1-CE2 3.75Å; I127-Y136 VanDerWaalsContact CD1-CZ 3.48Å; I127-Y136 HydrophobicContact CG1-CE2 3.83Å; I127-Y136 HydrophobicContact CG2-CD2 4.02Å; I127-Y136 HydrophobicContact CG2-CE2 3.97Å; D131-Y136 HydrophobicContact CB-CD2 4.48Å; D131-Y136 HydrophobicContact CB-CE2 4.31Å; D131-Y136 WeakPolarHBondContact O-CD2 3.31Å; D131-Y136 PolarHBondContact O-N 3.47Å; Y132-Y136 PolarHBondContact O-N 3.21Å; Y136-K139 WeakPolarHBondContact O-CB 3.36Å; Y136-K139 PolarHBondContact O-N 2.95Å; Y136-K139 VanDerWaalsContact O-N 3.12Å; Y136-L140 PolarHBondContact O-N 3.23Å; Y136-K169 HydrophobicContact CE1-CD 4.47Å; Y136-C170 VanDerWaalsContact CB-SG 3.56Å
137	W	96.6	Very high	93.8	Very high	38 Å²	38	53 Å²	53	14%	0.144	28%	0.279	C	S	.	.	H	α-helix	trans	-56.5	-44	-179.8	179.1	-107.8	0	0	0	112.9	Y132 K139 L140 D141 I144 M179 D182 L183 K186	Y132-W137 HydrophobicContact CE1-CB 4.15Å; Y132-W137 HydrophobicContact CE2-CB 4.25Å; Y132-W137 HydrophobicContact CE2-CE3 4.49Å; Y132-W137 WeakPolarHBondContact O-CB 3.5Å; Y132-W137 PolarHBondContact O-N 3.31Å; W137-K139 PolarHBondContact O-N 3.18Å; W137-K139 VanDerWaalsContact O-N 3.13Å; W137-L140 HydrophobicContact CE3-CB 4.15Å; W137-L140 HydrophobicContact CE3-CD1 4.22Å; W137-L140 HydrophobicContact CZ3-CB 4.26Å; W137-L140 HydrophobicContact CZ3-CD1 4.48Å; W137-L140 CarbonylContact O-C 3.58Å; W137-L140 PolarHBondContact O-N 3.2Å; W137-D141 HydrophobicContact CZ2-CB 4.19Å; W137-D141 WeakPolarHBondContact O-CB 3.37Å; W137-D141 PolarHBondContact O-N 2.95Å; W137-I144 HydrophobicContact CH2-CD1 4.01Å; W137-I144 HydrophobicContact CZ3-CD1 4.46Å; W137-M179 HydrophobicContact CZ3-CG 4.42Å; W137-D182 HydrophobicContact CD2-CB 3.95Å; W137-D182 HydrophobicContact CE3-CB 3.9Å; W137-D182 HydrophobicContact CH2-CB 3.51Å; W137-D182 HydrophobicContact CZ2-CB 3.54Å; W137-D182 HydrophobicContact CZ3-CB 3.68Å; W137-L183 HydrophobicContact CH2-CB 4.46Å; W137-K186 HydrophobicContact CZ2-CB 4.18Å
138	P	96.7	Very high	94.3	Very high	62 Å²	62	52.5 Å²	52.5	40%	0.403	28%	0.276	S	S	.	.	H	α-helix	trans	-59.8	-29.7	179.1	-27.1	37.9	0	0	0	113.8	K133 G142	K133-P138 VanDerWaalsContact O-CD 3.27Å; K133-P138 WeakPolarHBondContact O-CD 3.37Å; K133-P138 WeakPolarHBondContact O-CG 3.49Å; P138-G142 PolarHBondContact O-N 3.02Å
139	K	95	Very high	94.4	Very high	122 Å²	122	52.7 Å²	52.7	53%	0.53	28%	0.277	S	S	.	.	H	α-helix	trans	-71.2	-42.9	174.8	-62.6	175.8	-176.9	175.7	0	111.5	T135 Y136 W137 A143	T135-K139 WeakPolarHBondContact O-CD 3.48Å; T135-K139 VanDerWaalsContact O-CE 3.31Å; T135-K139 WeakPolarHBondContact O-CE 3.4Å; T135-K139 WeakPolarHBondContact O-CG 3.47Å; Y136-K139 WeakPolarHBondContact O-CB 3.36Å; Y136-K139 PolarHBondContact O-N 2.95Å; Y136-K139 VanDerWaalsContact O-N 3.12Å; W137-K139 PolarHBondContact O-N 3.18Å; W137-K139 VanDerWaalsContact O-N 3.13Å; K139-A143 WeakPolarHBondContact O-CB 3.49Å; K139-A143 PolarHBondContact O-N 2.98Å; K139-A143 VanDerWaalsContact O-N 3.14Å
140	L	96.8	Very high	94.2	Very high	1 Å²	1	50.3 Å²	50.3	1%	0.005	26%	0.264	C	S	.	.	H	α-helix	trans	-66	-47.1	175.8	-60	-178.3	0	0	0	110.5	Y136 W137 G142 A143 I144 I163 C166 V167 M179 F228	Y136-L140 PolarHBondContact O-N 3.23Å; W137-L140 HydrophobicContact CE3-CB 4.15Å; W137-L140 HydrophobicContact CE3-CD1 4.22Å; W137-L140 HydrophobicContact CZ3-CB 4.26Å; W137-L140 HydrophobicContact CZ3-CD1 4.48Å; W137-L140 CarbonylContact O-C 3.58Å; W137-L140 PolarHBondContact O-N 3.2Å; L140-G142 PolarHBondContact O-N 2.86Å; L140-A143 PolarHBondContact O-N 3.44Å; L140-I144 WeakPolarHBondContact O-CD1 3.39Å; L140-I144 WeakPolarHBondContact O-CG1 3.47Å; L140-I144 PolarHBondContact O-N 3.24Å; L140-I163 HydrophobicContact CD2-CG2 3.79Å; L140-C166 HydrophobicContact CD2-CB 3.89Å; L140-V167 HydrophobicContact CD1-CG2 4.23Å; L140-V167 HydrophobicContact CD2-CG2 3.71Å; L140-M179 HydrophobicContact CD1-CE 4.2Å; L140-M179 HydrophobicContact CD1-CG 4.3Å; L140-M179 HydrophobicContact CD1-SD 4.19Å; L140-F228 HydrophobicContact CB-CZ 4.46Å; L140-F228 HydrophobicContact CD1-CE1 4.35Å; L140-F228 HydrophobicContact CD1-CZ 4.48Å; L140-F228 HydrophobicContact CD2-CZ 4.5Å
141	D	96.4	Very high	93.4	Very high	46 Å²	46	47.1 Å²	47.1	25%	0.246	26%	0.256	C	S	.	.	H	α-helix	trans	-57.4	-47.8	179	-174.1	69.5	0	0	0	112.1	W137 A143 I144 D145 K186	W137-D141 HydrophobicContact CZ2-CB 4.19Å; W137-D141 WeakPolarHBondContact O-CB 3.37Å; W137-D141 PolarHBondContact O-N 2.95Å; D141-A143 PolarHBondContact O-N 3.3Å; D141-I144 PolarHBondContact O-N 2.94Å; D141-D145 WeakPolarHBondContact O-CB 3.49Å; D141-D145 PolarHBondContact O-N 3.37Å; D141-K186 WeakPolarHBondContact OD1-CD 3.3Å; D141-K186 WeakPolarHBondContact OD1-CE 3.41Å; D141-K186 WeakPolarHBondContact OD1-CG 3.34Å; D141-K186 IonicContact OD1-NZ 2.89Å; D141-K186 PolarHBondContact OD1-NZ 3.19Å; D141-K186 IonicContact OD2-NZ 3.35Å; D141-K186 PolarHBondContact OD2-NZ 3.42Å
142	G	95.1	Very high	92.1	Very high	28 Å²	28	50.1 Å²	50.1	29%	0.289	28%	0.279	S	S	.	.	H	α-helix	trans	-64.4	-38.1	176.9	0	0	0	0	0	112.9	P138 L140 Q146	P138-G142 PolarHBondContact O-N 3.02Å; L140-G142 PolarHBondContact O-N 2.86Å; G142-Q146 WeakPolarHBondContact O-CG 3.3Å; G142-Q146 PolarHBondContact O-N 3.24Å; G142-Q146 VanDerWaalsContact O-N 3.12Å
143	A	95.7	Very high	90.7	Very high	6 Å²	6	54 Å²	54	5%	0.05	32%	0.318	C	S	.	.	H	α-helix	trans	-67.1	-44.6	175.1	0	0	0	0	0	112	K139 L140 D141 D145 Q146 L147 I158 I163	K139-A143 WeakPolarHBondContact O-CB 3.49Å; K139-A143 PolarHBondContact O-N 2.98Å; K139-A143 VanDerWaalsContact O-N 3.14Å; L140-A143 PolarHBondContact O-N 3.44Å; D141-A143 PolarHBondContact O-N 3.3Å; A143-D145 VanDerWaalsContact C-N 3.31Å; A143-D145 PolarHBondContact O-N 3.22Å; A143-Q146 PolarHBondContact O-N 3.02Å; A143-L147 VanDerWaalsContact O-CG 3.29Å; A143-L147 WeakPolarHBondContact O-CG 3.47Å; A143-L147 PolarHBondContact O-N 2.69Å; A143-I158 HydrophobicContact CB-CD1 3.99Å; A143-I158 HydrophobicContact CB-CG1 4.37Å; A143-I158 HydrophobicContact CB-CG2 4.24Å; A143-I158 WeakPolarHBondContact O-CD1 3.27Å; A143-I163 HydrophobicContact CB-CD1 3.63Å; A143-I163 HydrophobicContact CB-CG1 3.8Å; A143-I163 HydrophobicContact CB-CG2 4.33Å
144	I	96.6	Very high	89.8	Confident	2 Å²	2	53 Å²	53	1%	0.01	32%	0.319	C	S	.	.	H	α-helix	trans	-60.2	-44.1	176.2	-66.4	156.6	0	0	0	110.1	W137 L140 D141 Q146 L147 L148 L183 K186 I187 I224 F228	W137-I144 HydrophobicContact CH2-CD1 4.01Å; W137-I144 HydrophobicContact CZ3-CD1 4.46Å; L140-I144 WeakPolarHBondContact O-CD1 3.39Å; L140-I144 WeakPolarHBondContact O-CG1 3.47Å; L140-I144 PolarHBondContact O-N 3.24Å; D141-I144 PolarHBondContact O-N 2.94Å; I144-Q146 VanDerWaalsContact C-N 3.34Å; I144-Q146 PolarHBondContact O-N 3.29Å; I144-L147 PolarHBondContact O-N 3.41Å; I144-L148 HydrophobicContact CG2-CD1 3.63Å; I144-L148 HydrophobicContact CG2-CG 4.17Å; I144-L148 WeakPolarHBondContact O-CB 3.48Å; I144-L148 VanDerWaalsContact O-CG 3.27Å; I144-L148 WeakPolarHBondContact O-CG 3.46Å; I144-L148 PolarHBondContact O-N 2.98Å; I144-L183 HydrophobicContact CD1-CD1 3.5Å; I144-L183 VanDerWaalsContact CD1-CD1 3.5Å; I144-L183 HydrophobicContact CG1-CD1 4.12Å; I144-K186 HydrophobicContact CG2-CG 4.01Å; I144-I187 HydrophobicContact CG2-CG1 4.27Å; I144-I224 HydrophobicContact CG2-CD1 4.45Å; I144-F228 HydrophobicContact CD1-CE2 4.21Å; I144-F228 HydrophobicContact CD1-CZ 3.89Å; I144-F228 HydrophobicContact CG1-CE2 4.13Å; I144-F228 HydrophobicContact CG1-CZ 4.28Å
145	D	95.2	Very high	88.9	Confident	56 Å²	56	59.7 Å²	59.7	30%	0.299	34%	0.335	S	S	.	.	H	α-helix	trans	-60.2	-44.6	179.4	-158.6	68	0	0	0	111.9	D141 A143 L148 T149 K186	D141-D145 WeakPolarHBondContact O-CB 3.49Å; D141-D145 PolarHBondContact O-N 3.37Å; A143-D145 VanDerWaalsContact C-N 3.31Å; A143-D145 PolarHBondContact O-N 3.22Å; D145-L148 PolarHBondContact O-N 2.9Å; D145-T149 WeakPolarHBondContact O-CB 3.39Å; D145-T149 WeakPolarHBondContact O-CG2 3.18Å; D145-T149 PolarHBondContact O-N 3.45Å; D145-T149 PolarHBondContact O-OG1 3.43Å; D145-K186 IonicContact OD1-NZ 3.7Å; D145-K186 PolarHBondContact OD1-NZ 3.02Å
146	Q	93.9	Very high	88	Confident	77 Å²	77	57.9 Å²	57.9	36%	0.36	32%	0.323	S	S	.	.	H	α-helix	trans	-63.7	-42.6	175.6	-74.6	177.5	26.3	0	0	112.3	G142 A143 I144 L148 T149 Q150 I158	G142-Q146 WeakPolarHBondContact O-CG 3.3Å; G142-Q146 PolarHBondContact O-N 3.24Å; G142-Q146 VanDerWaalsContact O-N 3.12Å; A143-Q146 PolarHBondContact O-N 3.02Å; I144-Q146 VanDerWaalsContact C-N 3.34Å; I144-Q146 PolarHBondContact O-N 3.29Å; Q146-L148 VanDerWaalsContact C-N 3.34Å; Q146-L148 PolarHBondContact O-N 3.48Å; Q146-T149 PolarHBondContact O-N 3.31Å; Q146-T149 PolarHBondContact O-OG1 2.95Å; Q146-Q150 WeakPolarHBondContact O-CB 3.24Å; Q146-Q150 PolarHBondContact O-N 3.31Å; Q146-Q150 VanDerWaalsContact O-N 3.12Å; Q146-I158 HydrophobicContact CB-CD1 3.81Å; Q146-I158 HydrophobicContact CB-CG1 4.4Å
147	L	94.2	Very high	87.3	Confident	2 Å²	2	59.7 Å²	59.7	1%	0.01	34%	0.341	C	S	.	.	H	α-helix	trans	-64.1	-38.9	177.1	-69.3	173.5	0	0	0	112.1	A143 I144 I156 I158 A220 I224 L227	A143-L147 VanDerWaalsContact O-CG 3.29Å; A143-L147 WeakPolarHBondContact O-CG 3.47Å; A143-L147 PolarHBondContact O-N 2.69Å; I144-L147 PolarHBondContact O-N 3.41Å; L147-I156 HydrophobicContact CD2-CD1 3.75Å; L147-I158 HydrophobicContact CD1-CD1 4.49Å; L147-I158 HydrophobicContact CD2-CD1 3.97Å; L147-I158 HydrophobicContact CG-CD1 3.79Å; L147-A220 VanDerWaalsContact O-CB 3.25Å; L147-A220 WeakPolarHBondContact O-CB 3.28Å; L147-I224 HydrophobicContact CB-CD1 4.35Å; L147-I224 HydrophobicContact CB-CG1 4.17Å; L147-I224 HydrophobicContact CD1-CG1 3.69Å; L147-L227 HydrophobicContact CD1-CD1 3.65Å
148	L	94.9	Very high	86.8	Confident	2 Å²	2	58.8 Å²	58.8	1%	0.01	34%	0.339	C	S	.	.	H	α-helix	trans	-74.7	-23.8	179.4	-69.9	171.4	0	0	0	113.2	I144 D145 Q146 I187 H190 Q216 Y217 A220 I224	I144-L148 HydrophobicContact CG2-CD1 3.63Å; I144-L148 HydrophobicContact CG2-CG 4.17Å; I144-L148 WeakPolarHBondContact O-CB 3.48Å; I144-L148 VanDerWaalsContact O-CG 3.27Å; I144-L148 WeakPolarHBondContact O-CG 3.46Å; I144-L148 PolarHBondContact O-N 2.98Å; D145-L148 PolarHBondContact O-N 2.9Å; Q146-L148 VanDerWaalsContact C-N 3.34Å; Q146-L148 PolarHBondContact O-N 3.48Å; L148-I187 HydrophobicContact CD1-CG1 4.18Å; L148-H190 HydrophobicContact CD1-CB 4.03Å; L148-Q216 PolarHBondContact O-NE2 3.24Å; L148-Y217 HydrophobicContact CD2-CD2 3.85Å; L148-Y217 HydrophobicContact CD2-CE2 3.88Å; L148-A220 HydrophobicContact CD2-CB 4.06Å; L148-I224 HydrophobicContact CD2-CD1 3.95Å; L148-I224 HydrophobicContact CG-CD1 4.19Å
149	T	92.4	Very high	86.6	Confident	71 Å²	71	58.1 Å²	58.1	44%	0.436	34%	0.336	S	S	.	.	H	α-helix	trans	-102.9	-4.8	-175	53.9	0	0	0	0	114.1	D145 Q146 Q216	D145-T149 WeakPolarHBondContact O-CB 3.39Å; D145-T149 WeakPolarHBondContact O-CG2 3.18Å; D145-T149 PolarHBondContact O-N 3.45Å; D145-T149 PolarHBondContact O-OG1 3.43Å; Q146-T149 PolarHBondContact O-N 3.31Å; Q146-T149 PolarHBondContact O-OG1 2.95Å; T149-Q216 VanDerWaalsContact C-NE2 3.34Å; T149-Q216 VanDerWaalsContact CA-NE2 3.3Å; T149-Q216 PolarHBondContact O-NE2 3.44Å
150	Q	84.6	Confident	86.5	Confident	57 Å²	57	57.2 Å²	57.2	27%	0.266	33%	0.33	S	S	.	.	P	Polyproline II helix	trans	-66.9	138.2	-176.7	-168.9	-154	-0.5	0	0	112.7	Q146 D154 I156	Q146-Q150 WeakPolarHBondContact O-CB 3.24Å; Q146-Q150 PolarHBondContact O-N 3.31Å; Q146-Q150 VanDerWaalsContact O-N 3.12Å; Q150-D154 HydrophobicContact CG-CB 4.23Å; Q150-D154 PolarHBondContact NE2-O 2.98Å; Q150-I156 HydrophobicContact CG-CD1 4.11Å; Q150-I156 HydrophobicContact CG-CG1 3.77Å
151	S	74.4	Confident	86.3	Confident	62 Å²	62	64.3 Å²	64.3	43%	0.434	36%	0.363	S	S	.	.	P	Polyproline II helix	trans	-85.9	147.2	166.4	-39.3	0	0	0	0	111.3	G153 D154	S151-G153 PolarHBondContact O-N 2.82Å; S151-G153 VanDerWaalsContact O-N 3.16Å; S151-D154 WeakPolarHBondContact CB-OD2 3.43Å; S151-D154 PolarHBondContact O-N 3.14Å; S151-D154 VanDerWaalsContact O-N 3.15Å; S151-D154 PolarHBondContact OG-OD2 2.86Å
152	P	65.1	Low	86.2	Confident	128 Å²	128	68.8 Å²	68.8	83%	0.831	38%	0.382	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.9	121.4	174.6	-23.4	33.3	0	0	0	111.7
153	G	65.7	Low	86.3	Confident	80 Å²	80	68.1 Å²	68.1	83%	0.825	37%	0.372	S	S	*	.	T	Hydrogen-bonded Turn	trans	100.2	-9.9	179.3	0	0	0	0	0	115.5	S151	S151-G153 PolarHBondContact O-N 2.82Å; S151-G153 VanDerWaalsContact O-N 3.16Å
154	D	74.9	Confident	86.3	Confident	92 Å²	92	72.1 Å²	72.1	49%	0.492	39%	0.387	S	S	.	.	P	Polyproline II helix	trans	-76.2	139.8	175.7	-72.6	-26.2	0	0	0	111.5	Q150 S151 I156	Q150-D154 HydrophobicContact CG-CB 4.23Å; Q150-D154 PolarHBondContact NE2-O 2.98Å; S151-D154 WeakPolarHBondContact CB-OD2 3.43Å; S151-D154 PolarHBondContact O-N 3.14Å; S151-D154 VanDerWaalsContact O-N 3.15Å; S151-D154 PolarHBondContact OG-OD2 2.86Å; D154-I156 PolarHBondContact O-N 2.86Å
155	Y	74.4	Confident	86.3	Confident	206 Å²	206	74.2 Å²	74.2	81%	0.808	40%	0.401	S	S	*	.	P	Polyproline II helix	trans	-69.3	124.3	171	174.2	-98.4	0	0	0	110.3	P157	Y155-P157 HydrophobicContact CE1-CB 3.99Å; Y155-P157 WeakPolarHBondContact O-CD 3.36Å
156	I	75.6	Confident	86.3	Confident	23 Å²	23	72 Å²	72	12%	0.118	39%	0.39	C	S	.	.	P	Polyproline II helix	trans	-92.1	118	175.5	-47.1	174.3	0	0	0	109.2	L147 Q150 D154 I158	L147-I156 HydrophobicContact CD2-CD1 3.75Å; Q150-I156 HydrophobicContact CG-CD1 4.11Å; Q150-I156 HydrophobicContact CG-CG1 3.77Å; D154-I156 PolarHBondContact O-N 2.86Å; I156-I158 HydrophobicContact CG2-CB 3.96Å; I156-I158 HydrophobicContact CG2-CD1 3.37Å; I156-I158 HydrophobicContact CG2-CG1 3.52Å; I156-I158 PolarHBondContact O-N 3.5Å
157	P	79.9	Confident	86.5	Confident	93 Å²	93	68.3 Å²	68.3	60%	0.604	37%	0.373	S	S	*	.			trans	-79.8	48.7	176.9	35.3	-36.3	0	0	0	112.1	Y155	Y155-P157 HydrophobicContact CE1-CB 3.99Å; Y155-P157 WeakPolarHBondContact O-CD 3.36Å
158	I	86.1	Confident	86.6	Confident	19 Å²	19	73.4 Å²	73.4	10%	0.097	39%	0.393	C	S	.	.			trans	-110.1	131.6	175.1	-62.7	166.5	0	0	0	109.5	A143 Q146 L147 I156 Y160 I163	A143-I158 HydrophobicContact CB-CD1 3.99Å; A143-I158 HydrophobicContact CB-CG1 4.37Å; A143-I158 HydrophobicContact CB-CG2 4.24Å; A143-I158 WeakPolarHBondContact O-CD1 3.27Å; Q146-I158 HydrophobicContact CB-CD1 3.81Å; Q146-I158 HydrophobicContact CB-CG1 4.4Å; L147-I158 HydrophobicContact CD1-CD1 4.49Å; L147-I158 HydrophobicContact CD2-CD1 3.97Å; L147-I158 HydrophobicContact CG-CD1 3.79Å; I156-I158 HydrophobicContact CG2-CB 3.96Å; I156-I158 HydrophobicContact CG2-CD1 3.37Å; I156-I158 HydrophobicContact CG2-CG1 3.52Å; I156-I158 PolarHBondContact O-N 3.5Å; I158-Y160 PolarHBondContact O-N 3.13Å; I158-I163 HydrophobicContact CG2-CD1 4.44Å; I158-I163 HydrophobicContact CG2-CG1 3.51Å
159	S	91.6	Very high	86.6	Confident	47 Å²	47	78.7 Å²	78.7	33%	0.329	42%	0.416	S	S	.	.			trans	-83.3	103.5	165.1	175.9	0	0	0	0	109.8	E161 Q162 I163	S159-E161 PolarHBondContact O-N 3.11Å; S159-Q162 PolarHBondContact O-N 3.4Å; S159-Q162 VanDerWaalsContact O-N 3.11Å; S159-Q162 WeakPolarHBondContact OG-CG 3.26Å; S159-Q162 PolarHBondContact OG-N 3.35Å; S159-I163 WeakPolarHBondContact O-CG1 3.49Å; S159-I163 PolarHBondContact O-N 3.44Å; S159-I163 VanDerWaalsContact O-N 3.08Å
160	Y	92.2	Very high	86.7	Confident	103 Å²	103	75.3 Å²	75.3	40%	0.404	40%	0.395	S	S	.	.	H	α-helix	trans	-54.6	-39.8	176.4	-75.4	-91.1	0	0	0	112.1	I158 Q162 I163 Y164 S223 L227	I158-Y160 PolarHBondContact O-N 3.13Å; Y160-Q162 PolarHBondContact O-N 3.27Å; Y160-I163 PolarHBondContact O-N 2.83Å; Y160-Y164 VanDerWaalsContact O-CB 3.23Å; Y160-Y164 WeakPolarHBondContact O-CB 3.41Å; Y160-Y164 PolarHBondContact O-N 2.9Å; Y160-S223 PolarHBondContact OH-OG 3.48Å; Y160-L227 HydrophobicContact CD1-CD1 4.05Å; Y160-L227 HydrophobicContact CD1-CD2 3.7Å; Y160-L227 HydrophobicContact CD1-CG 3.95Å; Y160-L227 HydrophobicContact CE1-CD1 4.12Å; Y160-L227 HydrophobicContact CE1-CG 4.36Å; Y160-L227 HydrophobicContact CG-CD2 4.42Å
161	E	93.6	Very high	87.2	Confident	151 Å²	151	73.3 Å²	73.3	71%	0.706	39%	0.386	S	S	*	.	H	α-helix	trans	-60.9	-44.4	177.2	-173.8	-173.3	168.6	0	0	112.2	S159 S165	S159-E161 PolarHBondContact O-N 3.11Å; E161-S165 WeakPolarHBondContact O-CB 3.2Å; E161-S165 PolarHBondContact O-N 3.48Å; E161-S165 PolarHBondContact O-OG 2.97Å
162	Q	94.6	Very high	88.2	Confident	139 Å²	139	73.1 Å²	73.1	65%	0.65	38%	0.384	S	S	*	.	H	α-helix	trans	-67.5	-42.3	179.8	-71.5	177.3	-10.8	0	0	111.8	S159 Y160 S165 C166	S159-Q162 PolarHBondContact O-N 3.4Å; S159-Q162 VanDerWaalsContact O-N 3.11Å; S159-Q162 WeakPolarHBondContact OG-CG 3.26Å; S159-Q162 PolarHBondContact OG-N 3.35Å; Y160-Q162 PolarHBondContact O-N 3.27Å; Q162-S165 PolarHBondContact O-N 3.2Å; Q162-C166 VanDerWaalsContact O-CB 3.29Å; Q162-C166 WeakPolarHBondContact O-CB 3.44Å; Q162-C166 PolarHBondContact O-N 3.13Å
163	I	96.4	Very high	89.5	Confident	15 Å²	15	70 Å²	70	8%	0.077	36%	0.359	C	S	.	.	H	α-helix	trans	-67.4	-46.9	179.1	-60.1	-52.5	0	0	0	110.5	L140 A143 I158 S159 Y160 S165 C166 V167 L227	L140-I163 HydrophobicContact CD2-CG2 3.79Å; A143-I163 HydrophobicContact CB-CD1 3.63Å; A143-I163 HydrophobicContact CB-CG1 3.8Å; A143-I163 HydrophobicContact CB-CG2 4.33Å; I158-I163 HydrophobicContact CG2-CD1 4.44Å; I158-I163 HydrophobicContact CG2-CG1 3.51Å; S159-I163 WeakPolarHBondContact O-CG1 3.49Å; S159-I163 PolarHBondContact O-N 3.44Å; S159-I163 VanDerWaalsContact O-N 3.08Å; Y160-I163 PolarHBondContact O-N 2.83Å; I163-S165 VanDerWaalsContact C-N 3.34Å; I163-S165 PolarHBondContact O-N 3.5Å; I163-C166 VanDerWaalsContact O-CB 3.25Å; I163-C166 WeakPolarHBondContact O-CB 3.41Å; I163-C166 PolarHBondContact O-N 3.12Å; I163-C166 VanDerWaalsContact O-N 3.11Å; I163-V167 WeakPolarHBondContact O-CG2 3.29Å; I163-V167 PolarHBondContact O-N 3.03Å; I163-L227 HydrophobicContact CB-CD2 3.97Å; I163-L227 HydrophobicContact CG2-CD1 4.08Å; I163-L227 HydrophobicContact CG2-CD2 3.93Å; I163-L227 HydrophobicContact CG2-CG 4.42Å
164	Y	96.5	Very high	90.8	Very high	90 Å²	90	74.7 Å²	74.7	35%	0.353	36%	0.359	S	S	.	.	H	α-helix	trans	-59.2	-44.7	175.1	179.6	-99.5	0	0	0	112	Y160 C166 V167 Y168 I229	Y160-Y164 VanDerWaalsContact O-CB 3.23Å; Y160-Y164 WeakPolarHBondContact O-CB 3.41Å; Y160-Y164 PolarHBondContact O-N 2.9Å; Y164-C166 VanDerWaalsContact C-N 3.28Å; Y164-C166 PolarHBondContact O-N 3.03Å; Y164-V167 PolarHBondContact O-N 3.04Å; Y164-Y168 WeakPolarHBondContact O-CB 3.48Å; Y164-Y168 PolarHBondContact O-N 3.11Å; Y164-I229 HydrophobicContact CE2-CG2 3.8Å
165	S	95.7	Very high	91.7	Very high	45 Å²	45	71.3 Å²	71.3	32%	0.315	34%	0.341	S	S	.	.	H	α-helix	trans	-61.2	-36.5	175.2	-64.7	0	0	0	0	112.5	E161 Q162 I163 K169	E161-S165 WeakPolarHBondContact O-CB 3.2Å; E161-S165 PolarHBondContact O-N 3.48Å; E161-S165 PolarHBondContact O-OG 2.97Å; Q162-S165 PolarHBondContact O-N 3.2Å; I163-S165 VanDerWaalsContact C-N 3.34Å; I163-S165 PolarHBondContact O-N 3.5Å; S165-K169 WeakPolarHBondContact O-CB 3.49Å; S165-K169 VanDerWaalsContact O-CG 3.29Å; S165-K169 WeakPolarHBondContact O-CG 3.37Å; S165-K169 PolarHBondContact O-N 2.82Å
166	C	95.8	Very high	92.7	Very high	10 Å²	10	62.1 Å²	62.1	7%	0.068	31%	0.306	C	S	.	.	H	α-helix	trans	-64	-48.1	175.8	-172	0	0	0	0	110.9	L140 Q162 I163 Y164 K169 C170	L140-C166 HydrophobicContact CD2-CB 3.89Å; Q162-C166 VanDerWaalsContact O-CB 3.29Å; Q162-C166 WeakPolarHBondContact O-CB 3.44Å; Q162-C166 PolarHBondContact O-N 3.13Å; I163-C166 VanDerWaalsContact O-CB 3.25Å; I163-C166 WeakPolarHBondContact O-CB 3.41Å; I163-C166 PolarHBondContact O-N 3.12Å; I163-C166 VanDerWaalsContact O-N 3.11Å; Y164-C166 VanDerWaalsContact C-N 3.28Å; Y164-C166 PolarHBondContact O-N 3.03Å; C166-K169 PolarHBondContact O-N 2.92Å; C166-C170 PolarHBondContact O-N 2.92Å; C166-C170 VanDerWaalsContact O-N 3.08Å; C166-C170 PolarHBondContact O-SG 3.09Å
167	V	97.1	Very high	93.7	Very high	0 Å²	0	67.2 Å²	67.2	0%	0	33%	0.329	C	S	.	.	H	α-helix	trans	-58.4	-51.8	175.4	172.8	0	0	0	0	110.6	L140 I163 Y164 K169 C170 V171 M179 F228 M231	L140-V167 HydrophobicContact CD1-CG2 4.23Å; L140-V167 HydrophobicContact CD2-CG2 3.71Å; I163-V167 WeakPolarHBondContact O-CG2 3.29Å; I163-V167 PolarHBondContact O-N 3.03Å; Y164-V167 PolarHBondContact O-N 3.04Å; V167-K169 VanDerWaalsContact C-N 3.34Å; V167-K169 PolarHBondContact O-N 3.4Å; V167-C170 PolarHBondContact O-N 3.47Å; V167-V171 HydrophobicContact CG1-CG2 4.21Å; V167-V171 WeakPolarHBondContact O-CG2 3.14Å; V167-V171 PolarHBondContact O-N 3.49Å; V167-M179 HydrophobicContact CB-SD 4.47Å; V167-M179 HydrophobicContact CG1-CE 4.33Å; V167-M179 HydrophobicContact CG1-SD 3.93Å; V167-M179 HydrophobicContact CG2-SD 4.3Å; V167-F228 HydrophobicContact CG1-CD1 4.17Å; V167-F228 HydrophobicContact CG2-CD1 3.85Å; V167-F228 HydrophobicContact CG2-CE1 3.7Å; V167-F228 HydrophobicContact CG2-CG 4.38Å; V167-F228 HydrophobicContact CG2-CZ 4.08Å; V167-M231 HydrophobicContact CG1-CB 4.37Å
168	Y	96.6	Very high	94.5	Very high	108 Å²	108	66.3 Å²	66.3	42%	0.424	32%	0.317	S	S	.	.	H	α-helix	trans	-54.2	-49.1	-180	175.7	-95.4	0	0	0	112.1	Y164 C170 V171 C172 Y230	Y164-Y168 WeakPolarHBondContact O-CB 3.48Å; Y164-Y168 PolarHBondContact O-N 3.11Å; Y168-C170 PolarHBondContact O-N 3.31Å; Y168-V171 PolarHBondContact O-N 3.07Å; Y168-C172 WeakPolarHBondContact O-CB 3.27Å; Y168-C172 PolarHBondContact O-N 3.3Å; Y168-C172 PolarHBondContact O-SG 2.88Å; Y168-Y230 AromaticContact CD2-CD1 3.84Å; Y168-Y230 HydrophobicContact CD2-CD1 3.84Å; Y168-Y230 AromaticContact CD2-CD2 3.83Å; Y168-Y230 HydrophobicContact CD2-CD2 3.83Å; Y168-Y230 AromaticContact CD2-CE1 3.65Å; Y168-Y230 HydrophobicContact CD2-CE1 3.65Å; Y168-Y230 AromaticContact CD2-CE2 3.62Å; Y168-Y230 HydrophobicContact CD2-CE2 3.62Å; Y168-Y230 AromaticContact CD2-CG 3.93Å; Y168-Y230 HydrophobicContact CD2-CG 3.93Å; Y168-Y230 AromaticContact CD2-CZ 3.55Å; Y168-Y230 HydrophobicContact CE2-CD1 4.49Å; Y168-Y230 HydrophobicContact CE2-CD2 4.21Å; Y168-Y230 AromaticContact CE2-CE1 3.88Å; Y168-Y230 HydrophobicContact CE2-CE1 3.88Å; Y168-Y230 AromaticContact CE2-CE2 3.53Å; Y168-Y230 HydrophobicContact CE2-CE2 3.53Å; Y168-Y230 AromaticContact CE2-CZ 3.36Å; Y168-Y230 WeakPolarHBondContact CE2-OH 3.36Å
169	K	94.8	Very high	95	Very high	114 Å²	114	65.4 Å²	65.4	50%	0.496	31%	0.313	S	S	.	.	H	α-helix	trans	-60.2	-45.6	178.7	-75.3	174.9	-177.4	179.4	0	111.9	I127 Y136 S165 C166 V167 C172 Q173	I127-K169 HydrophobicContact CD1-CB 4.2Å; Y136-K169 HydrophobicContact CE1-CD 4.47Å; S165-K169 WeakPolarHBondContact O-CB 3.49Å; S165-K169 VanDerWaalsContact O-CG 3.29Å; S165-K169 WeakPolarHBondContact O-CG 3.37Å; S165-K169 PolarHBondContact O-N 2.82Å; C166-K169 PolarHBondContact O-N 2.92Å; V167-K169 VanDerWaalsContact C-N 3.34Å; V167-K169 PolarHBondContact O-N 3.4Å; K169-C172 PolarHBondContact O-N 2.68Å; K169-Q173 WeakPolarHBondContact O-CB 3.34Å; K169-Q173 WeakPolarHBondContact O-CG 3.24Å; K169-Q173 PolarHBondContact O-N 3.12Å; K169-Q173 VanDerWaalsContact O-N 3.14Å
170	C	95.4	Very high	95.4	Very high	0 Å²	0	64.8 Å²	64.8	0%	0	30%	0.303	C	S	.	.	H	α-helix	trans	-65.1	-40.5	-179.9	-68	0	0	0	0	112.2	Y136 C166 V167 Y168 Q173 Q174 H175 M179	Y136-C170 VanDerWaalsContact CB-SG 3.56Å; C166-C170 PolarHBondContact O-N 2.92Å; C166-C170 VanDerWaalsContact O-N 3.08Å; C166-C170 PolarHBondContact O-SG 3.09Å; V167-C170 PolarHBondContact O-N 3.47Å; Y168-C170 PolarHBondContact O-N 3.31Å; C170-Q173 CarbonylContact O-C 3.54Å; C170-Q173 PolarHBondContact O-N 3.37Å; C170-Q174 PolarHBondContact O-N 3.15Å; C170-H175 HydrophobicContact CB-CB 4.47Å; C170-H175 WeakPolarHBondContact O-CB 3.48Å; C170-H175 PolarHBondContact O-N 3.15Å; C170-M179 HydrophobicContact CB-CE 3.1Å
171	V	95.4	Very high	95.6	Very high	14 Å²	14	62.8 Å²	62.8	9%	0.085	31%	0.305	C	S	.	.	H	α-helix	trans	-65.8	-44.5	176.8	175.4	0	0	0	0	111.2	V167 Y168 Q173 Q174 M179 Y230 M231 F234	V167-V171 HydrophobicContact CG1-CG2 4.21Å; V167-V171 WeakPolarHBondContact O-CG2 3.14Å; V167-V171 PolarHBondContact O-N 3.49Å; Y168-V171 PolarHBondContact O-N 3.07Å; V171-Q173 PolarHBondContact O-N 3.13Å; V171-Q174 PolarHBondContact O-N 3.25Å; V171-M179 HydrophobicContact CG2-CE 4.12Å; V171-Y230 HydrophobicContact CB-CD1 3.7Å; V171-Y230 HydrophobicContact CB-CE1 3.9Å; V171-Y230 HydrophobicContact CG1-CD1 3.58Å; V171-Y230 HydrophobicContact CG1-CE1 3.56Å; V171-Y230 HydrophobicContact CG2-CD1 4.15Å; V171-M231 HydrophobicContact CG2-CB 3.89Å; V171-M231 HydrophobicContact CG2-CG 4.4Å; V171-F234 HydrophobicContact CG1-CB 4.06Å
172	C	94.1	Very high	95.9	Very high	58 Å²	58	56.9 Å²	56.9	39%	0.392	28%	0.278	S	S	.	.	H	α-helix	trans	-60.9	-26.8	176.7	-67.6	0	0	0	0	112.9	Y168 K169 Q174	Y168-C172 WeakPolarHBondContact O-CB 3.27Å; Y168-C172 PolarHBondContact O-N 3.3Å; Y168-C172 PolarHBondContact O-SG 2.88Å; K169-C172 PolarHBondContact O-N 2.68Å; C172-Q174 VanDerWaalsContact C-N 3.29Å
173	Q	92.6	Very high	96.1	Very high	64 Å²	64	50.3 Å²	50.3	30%	0.299	25%	0.247	S	C	.	.	T	Hydrogen-bonded Turn	trans	-93.1	19.7	177.6	-61.8	-66.2	-17.9	0	0	113	N125 I127 K169 C170 V171 H175	N125-Q173 PolarHBondContact O-NE2 3.23Å; N125-Q173 PolarHBondContact O-OE1 3.47Å; I127-Q173 HydrophobicContact CB-CB 3.92Å; I127-Q173 HydrophobicContact CB-CG 4.03Å; I127-Q173 HydrophobicContact CD1-CB 4.17Å; I127-Q173 HydrophobicContact CD1-CG 3.79Å; I127-Q173 HydrophobicContact CG1-CB 4.24Å; I127-Q173 HydrophobicContact CG1-CG 3.83Å; K169-Q173 WeakPolarHBondContact O-CB 3.34Å; K169-Q173 WeakPolarHBondContact O-CG 3.24Å; K169-Q173 PolarHBondContact O-N 3.12Å; K169-Q173 VanDerWaalsContact O-N 3.14Å; C170-Q173 CarbonylContact O-C 3.54Å; C170-Q173 PolarHBondContact O-N 3.37Å; V171-Q173 PolarHBondContact O-N 3.13Å; Q173-H175 VanDerWaalsContact C-N 3.33Å; Q173-H175 PolarHBondContact O-CD2 3.13Å; Q173-H175 VanDerWaalsContact O-CD2 3.3Å; Q173-H175 PolarHBondContact O-N 3.47Å
174	Q	93.2	Very high	96.2	Very high	178 Å²	178	51 Å²	51	83%	0.832	25%	0.251	S	S	*	.	T	Hydrogen-bonded Turn	trans	65.5	22.7	175.1	-52.5	-173	39.9	0	0	116	C170 V171 C172 S176	C170-Q174 PolarHBondContact O-N 3.15Å; V171-Q174 PolarHBondContact O-N 3.25Å; C172-Q174 VanDerWaalsContact C-N 3.29Å; Q174-S176 VanDerWaalsContact C-N 3.33Å; Q174-S176 PolarHBondContact O-N 2.96Å
175	H	94.6	Very high	96.3	Very high	21 Å²	21	52.9 Å²	52.9	10%	0.097	26%	0.261	C	S	.	.			trans	-92.2	18	174.7	-65.8	-73.8	0	0	0	113.7	I127 Y132 C170 Q173 E177 Q178 M179	I127-H175 PolarHBondContact O-NE2 3.14Å; Y132-H175 HydrophobicContact CD2-CB 4.09Å; Y132-H175 HydrophobicContact CE2-CB 4.43Å; C170-H175 HydrophobicContact CB-CB 4.47Å; C170-H175 WeakPolarHBondContact O-CB 3.48Å; C170-H175 PolarHBondContact O-N 3.15Å; Q173-H175 VanDerWaalsContact C-N 3.33Å; Q173-H175 PolarHBondContact O-CD2 3.13Å; Q173-H175 VanDerWaalsContact O-CD2 3.3Å; Q173-H175 PolarHBondContact O-N 3.47Å; H175-E177 PolarHBondContact O-N 3.07Å; H175-Q178 PolarHBondContact O-N 2.56Å; H175-M179 VanDerWaalsContact O-CB 3.24Å; H175-M179 WeakPolarHBondContact O-CB 3.47Å; H175-M179 PolarHBondContact O-N 3.22Å
176	S	95.8	Very high	96.4	Very high	12 Å²	12	52.4 Å²	52.4	8%	0.084	25%	0.253	C	S	.	.	H	α-helix	trans	-64.2	-41.1	-173.6	62	0	0	0	0	113.6	Q174 Y180 Y235	Q174-S176 VanDerWaalsContact C-N 3.33Å; Q174-S176 PolarHBondContact O-N 2.96Å; S176-Y180 WeakPolarHBondContact O-CB 3.48Å; S176-Y180 PolarHBondContact O-N 3.1Å; S176-Y235 WeakPolarHBondContact OG-CD2 3.34Å
177	E	96.2	Very high	96.5	Very high	130 Å²	130	52 Å²	52	61%	0.607	25%	0.25	S	C	*	.	H	α-helix	trans	-66.3	-47.8	178.9	174.5	171.4	-172.9	0	0	111.6	H175 M179 Y180 S181 Y235	H175-E177 PolarHBondContact O-N 3.07Å; E177-M179 PolarHBondContact O-N 3.12Å; E177-Y180 PolarHBondContact O-N 3.27Å; E177-S181 PolarHBondContact O-N 3.31Å; E177-Y235 HydrophobicContact CB-CE1 4.27Å; E177-Y235 HydrophobicContact CB-CE2 3.93Å; E177-Y235 WeakPolarHBondContact CG-OH 3.2Å
178	Q	96.8	Very high	96.6	Very high	75 Å²	75	52.9 Å²	52.9	35%	0.35	26%	0.256	S	S	.	.	H	α-helix	trans	-60.8	-45.5	176.8	-177	62.5	52.3	0	0	111	Y132 H175 Y180 S181 D182	Y132-Q178 HydrophobicContact CD1-CG 4.12Å; Y132-Q178 HydrophobicContact CE1-CB 4.47Å; Y132-Q178 HydrophobicContact CE1-CG 3.47Å; Y132-Q178 VanDerWaalsContact CE1-CG 3.47Å; H175-Q178 PolarHBondContact O-N 2.56Å; Q178-Y180 PolarHBondContact O-N 2.95Å; Q178-S181 PolarHBondContact O-N 3.06Å; Q178-D182 PolarHBondContact NE2-OD1 3.22Å; Q178-D182 PolarHBondContact NE2-OD2 2.9Å; Q178-D182 WeakPolarHBondContact O-CB 3.37Å; Q178-D182 VanDerWaalsContact O-CG 3.26Å; Q178-D182 PolarHBondContact O-N 3.19Å
179	M	97.1	Very high	96.7	Very high	0 Å²	0	51.4 Å²	51.4	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-61.7	-43.5	177.8	-173.8	-165.7	-57.8	0	0	112.6	Y132 W137 L140 V167 C170 V171 H175 E177 D182 L183 F228 M231	Y132-M179 HydrophobicContact CE2-CB 4.31Å; Y132-M179 VanDerWaalsContact OH-CA 3.28Å; Y132-M179 WeakPolarHBondContact OH-CA 3.42Å; W137-M179 HydrophobicContact CZ3-CG 4.42Å; L140-M179 HydrophobicContact CD1-CE 4.2Å; L140-M179 HydrophobicContact CD1-CG 4.3Å; L140-M179 HydrophobicContact CD1-SD 4.19Å; V167-M179 HydrophobicContact CB-SD 4.47Å; V167-M179 HydrophobicContact CG1-CE 4.33Å; V167-M179 HydrophobicContact CG1-SD 3.93Å; V167-M179 HydrophobicContact CG2-SD 4.3Å; C170-M179 HydrophobicContact CB-CE 3.1Å; V171-M179 HydrophobicContact CG2-CE 4.12Å; H175-M179 VanDerWaalsContact O-CB 3.24Å; H175-M179 WeakPolarHBondContact O-CB 3.47Å; H175-M179 PolarHBondContact O-N 3.22Å; E177-M179 PolarHBondContact O-N 3.12Å; M179-D182 PolarHBondContact O-N 3.09Å; M179-L183 VanDerWaalsContact O-CB 3.3Å; M179-L183 WeakPolarHBondContact O-CB 3.26Å; M179-L183 PolarHBondContact O-N 3.12Å; M179-F228 HydrophobicContact CG-CE1 4.05Å; M179-F228 HydrophobicContact SD-CD1 3.84Å; M179-F228 HydrophobicContact SD-CE1 3.62Å; M179-M231 HydrophobicContact CB-SD 3.9Å; M179-M231 HydrophobicContact CG-SD 3.75Å; M179-M231 HydrophobicContact SD-CB 4.5Å; M179-M231 HydrophobicContact SD-SD 3.57Å
180	Y	98.3	Very high	96.8	Very high	33 Å²	33	46.7 Å²	46.7	13%	0.129	23%	0.234	C	C	.	.	H	α-helix	trans	-61.3	-47.7	175	170	-98.8	0	0	0	110.9	S176 E177 Q178 D182 L183 I184 M231 Y235 I236 L240 R242 D247	S176-Y180 WeakPolarHBondContact O-CB 3.48Å; S176-Y180 PolarHBondContact O-N 3.1Å; E177-Y180 PolarHBondContact O-N 3.27Å; Q178-Y180 PolarHBondContact O-N 2.95Å; Y180-D182 VanDerWaalsContact C-N 3.31Å; Y180-D182 PolarHBondContact O-N 3.03Å; Y180-L183 PolarHBondContact O-N 3.46Å; Y180-I184 HydrophobicContact CD1-CG1 4.41Å; Y180-I184 HydrophobicContact CD2-CD1 4.47Å; Y180-I184 HydrophobicContact CD2-CG1 4.09Å; Y180-I184 HydrophobicContact CE1-CG1 3.99Å; Y180-I184 HydrophobicContact CE2-CD1 3.79Å; Y180-I184 HydrophobicContact CE2-CG1 3.67Å; Y180-I184 HydrophobicContact CG-CG1 4.45Å; Y180-I184 VanDerWaalsContact O-CG1 3.3Å; Y180-I184 WeakPolarHBondContact O-CG1 3.27Å; Y180-I184 PolarHBondContact O-N 2.79Å; Y180-M231 HydrophobicContact CD2-CE 4.37Å; Y180-Y235 HydrophobicContact CD1-CE1 4.03Å; Y180-Y235 HydrophobicContact CG-CD1 4.41Å; Y180-Y235 AromaticContact CG-CE1 3.97Å; Y180-Y235 HydrophobicContact CG-CE1 3.97Å; Y180-I236 HydrophobicContact CD2-CD1 3.54Å; Y180-I236 HydrophobicContact CD2-CG1 3.93Å; Y180-I236 HydrophobicContact CE2-CD1 3.85Å; Y180-I236 HydrophobicContact CE2-CG1 4.27Å; Y180-L240 HydrophobicContact CD1-CD1 4.44Å; Y180-L240 HydrophobicContact CE1-CD1 4.23Å; Y180-R242 PolarHBondContact OH-NH1 3.48Å; Y180-R242 PolarHBondContact OH-NH2 2.93Å; Y180-R242 VanDerWaalsContact OH-NH2 3.14Å; Y180-D247 PolarHBondContact OH-OD2 3.33Å
181	S	98.2	Very high	97	Very high	62 Å²	62	46.7 Å²	46.7	43%	0.434	24%	0.235	S	C	.	.	H	α-helix	trans	-58.6	-42.8	177.5	-179.1	0	0	0	0	112.3	E177 Q178 K185	E177-S181 PolarHBondContact O-N 3.31Å; Q178-S181 PolarHBondContact O-N 3.06Å; S181-K185 VanDerWaalsContact O-CB 3.27Å; S181-K185 WeakPolarHBondContact O-CB 3.42Å; S181-K185 PolarHBondContact O-N 2.87Å
182	D	98.2	Very high	97.1	Very high	27 Å²	27	49.3 Å²	49.3	14%	0.144	25%	0.246	C	C	.	.	H	α-helix	trans	-69.8	-38.5	-180	-68.5	-31.8	0	0	0	111.8	Y132 W137 Q178 M179 Y180 K185 K186	Y132-D182 VanDerWaalsContact CE1-OD2 3.28Å; Y132-D182 WeakPolarHBondContact CE1-OD2 3.39Å; Y132-D182 PolarHBondContact OH-OD2 3.41Å; W137-D182 HydrophobicContact CD2-CB 3.95Å; W137-D182 HydrophobicContact CE3-CB 3.9Å; W137-D182 HydrophobicContact CH2-CB 3.51Å; W137-D182 HydrophobicContact CZ2-CB 3.54Å; W137-D182 HydrophobicContact CZ3-CB 3.68Å; Q178-D182 PolarHBondContact NE2-OD1 3.22Å; Q178-D182 PolarHBondContact NE2-OD2 2.9Å; Q178-D182 WeakPolarHBondContact O-CB 3.37Å; Q178-D182 VanDerWaalsContact O-CG 3.26Å; Q178-D182 PolarHBondContact O-N 3.19Å; M179-D182 PolarHBondContact O-N 3.09Å; Y180-D182 VanDerWaalsContact C-N 3.31Å; Y180-D182 PolarHBondContact O-N 3.03Å; D182-K185 PolarHBondContact O-N 3.09Å; D182-K186 VanDerWaalsContact O-CB 3.31Å; D182-K186 WeakPolarHBondContact O-CB 3.26Å; D182-K186 PolarHBondContact O-N 3.25Å
183	L	98.5	Very high	97.3	Very high	0 Å²	0	52 Å²	52	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-60.4	-52.2	174	176.5	64.3	0	0	0	111.4	W137 I144 M179 Y180 K185 K186 I187 F228 M231 L244	W137-L183 HydrophobicContact CH2-CB 4.46Å; I144-L183 HydrophobicContact CD1-CD1 3.5Å; I144-L183 VanDerWaalsContact CD1-CD1 3.5Å; I144-L183 HydrophobicContact CG1-CD1 4.12Å; M179-L183 VanDerWaalsContact O-CB 3.3Å; M179-L183 WeakPolarHBondContact O-CB 3.26Å; M179-L183 PolarHBondContact O-N 3.12Å; Y180-L183 PolarHBondContact O-N 3.46Å; L183-K185 VanDerWaalsContact C-N 3.33Å; L183-K185 PolarHBondContact O-N 3.5Å; L183-K186 PolarHBondContact O-N 2.95Å; L183-I187 HydrophobicContact CD1-CD1 3.61Å; L183-I187 HydrophobicContact CD1-CG1 4.24Å; L183-I187 HydrophobicContact CG-CD1 4.05Å; L183-I187 WeakPolarHBondContact O-CG1 3.15Å; L183-I187 PolarHBondContact O-N 3.47Å; L183-F228 HydrophobicContact CD1-CE2 4.27Å; L183-F228 HydrophobicContact CD1-CZ 4.24Å; L183-F228 HydrophobicContact CD2-CD1 4.1Å; L183-F228 HydrophobicContact CD2-CD2 4.41Å; L183-F228 HydrophobicContact CD2-CE1 4.32Å; L183-F228 HydrophobicContact CD2-CG 4.14Å; L183-M231 HydrophobicContact CD2-CE 3.69Å; L183-L244 HydrophobicContact CD2-CD1 3.99Å
184	I	98.6	Very high	97.6	Very high	30 Å²	30	50 Å²	50	15%	0.154	24%	0.24	C	C	.	.	H	α-helix	trans	-58.3	-48.9	178.2	-64.7	-60.6	0	0	0	109.6	Y180 K186 I187 T188 L248 L251	Y180-I184 HydrophobicContact CD1-CG1 4.41Å; Y180-I184 HydrophobicContact CD2-CD1 4.47Å; Y180-I184 HydrophobicContact CD2-CG1 4.09Å; Y180-I184 HydrophobicContact CE1-CG1 3.99Å; Y180-I184 HydrophobicContact CE2-CD1 3.79Å; Y180-I184 HydrophobicContact CE2-CG1 3.67Å; Y180-I184 HydrophobicContact CG-CG1 4.45Å; Y180-I184 VanDerWaalsContact O-CG1 3.3Å; Y180-I184 WeakPolarHBondContact O-CG1 3.27Å; Y180-I184 PolarHBondContact O-N 2.79Å; I184-K186 PolarHBondContact O-N 3.46Å; I184-I187 PolarHBondContact O-N 3.44Å; I184-T188 WeakPolarHBondContact O-CB 3.27Å; I184-T188 PolarHBondContact O-N 2.97Å; I184-T188 PolarHBondContact O-OG1 3.16Å; I184-L248 HydrophobicContact CD1-CD2 3.99Å; I184-L251 HydrophobicContact CD1-CD1 3.92Å; I184-L251 HydrophobicContact CG2-CD1 4.16Å; I184-L251 HydrophobicContact CG2-CD2 4.17Å
185	K	98.6	Very high	97.8	Very high	130 Å²	130	41.9 Å²	41.9	57%	0.565	20%	0.203	S	C	*	.	H	α-helix	trans	-59.3	-44.8	178.7	-176.6	178.2	179.8	179.9	0	112.8	S181 D182 L183 N189	S181-K185 VanDerWaalsContact O-CB 3.27Å; S181-K185 WeakPolarHBondContact O-CB 3.42Å; S181-K185 PolarHBondContact O-N 2.87Å; D182-K185 PolarHBondContact O-N 3.09Å; L183-K185 VanDerWaalsContact C-N 3.33Å; L183-K185 PolarHBondContact O-N 3.5Å; K185-N189 WeakPolarHBondContact O-CB 3.45Å; K185-N189 PolarHBondContact O-N 3.32Å; K185-N189 PolarHBondContact O-ND2 2.91Å
186	K	98.2	Very high	97.9	Very high	35 Å²	35	47.4 Å²	47.4	15%	0.152	23%	0.227	C	C	.	.	H	α-helix	trans	-60.9	-47.4	178.6	172.5	58.1	168.8	-144.8	0	111.2	W137 D141 I144 D145 D182 L183 I184 N189 H190	W137-K186 HydrophobicContact CZ2-CB 4.18Å; D141-K186 WeakPolarHBondContact OD1-CD 3.3Å; D141-K186 WeakPolarHBondContact OD1-CE 3.41Å; D141-K186 WeakPolarHBondContact OD1-CG 3.34Å; D141-K186 IonicContact OD1-NZ 2.89Å; D141-K186 PolarHBondContact OD1-NZ 3.19Å; D141-K186 IonicContact OD2-NZ 3.35Å; D141-K186 PolarHBondContact OD2-NZ 3.42Å; I144-K186 HydrophobicContact CG2-CG 4.01Å; D145-K186 IonicContact OD1-NZ 3.7Å; D145-K186 PolarHBondContact OD1-NZ 3.02Å; D182-K186 VanDerWaalsContact O-CB 3.31Å; D182-K186 WeakPolarHBondContact O-CB 3.26Å; D182-K186 PolarHBondContact O-N 3.25Å; L183-K186 PolarHBondContact O-N 2.95Å; I184-K186 PolarHBondContact O-N 3.46Å; K186-N189 PolarHBondContact O-N 3.2Å; K186-H190 PolarHBondContact O-N 3.38Å; K186-H190 VanDerWaalsContact O-N 3.11Å
187	I	98.5	Very high	98	Very high	0 Å²	0	52.3 Å²	52.3	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-67.2	-45	-179.7	-69.6	175.5	0	0	0	110.7	I144 L148 L183 I184 N189 H190 L191 Y217 L248 L251	I144-I187 HydrophobicContact CG2-CG1 4.27Å; L148-I187 HydrophobicContact CD1-CG1 4.18Å; L183-I187 HydrophobicContact CD1-CD1 3.61Å; L183-I187 HydrophobicContact CD1-CG1 4.24Å; L183-I187 HydrophobicContact CG-CD1 4.05Å; L183-I187 WeakPolarHBondContact O-CG1 3.15Å; L183-I187 PolarHBondContact O-N 3.47Å; I184-I187 PolarHBondContact O-N 3.44Å; I187-N189 VanDerWaalsContact C-N 3.35Å; I187-N189 PolarHBondContact O-N 3.04Å; I187-H190 WeakPolarHBondContact O-CB 3.41Å; I187-H190 PolarHBondContact O-N 3.32Å; I187-H190 VanDerWaalsContact O-N 3.14Å; I187-L191 HydrophobicContact CG2-CD1 3.8Å; I187-L191 HydrophobicContact CG2-CG 4.22Å; I187-L191 WeakPolarHBondContact O-CG 3.35Å; I187-L191 PolarHBondContact O-N 2.9Å; I187-Y217 HydrophobicContact CG2-CE2 3.87Å; I187-Y217 WeakPolarHBondContact CG2-OH 3.39Å; I187-L248 HydrophobicContact CD1-CD1 4.18Å; I187-L248 HydrophobicContact CD1-CD2 3.49Å; I187-L248 VanDerWaalsContact CD1-CD2 3.49Å; I187-L248 HydrophobicContact CD1-CG 4.45Å; I187-L251 HydrophobicContact CB-CD1 4.07Å; I187-L251 HydrophobicContact CG2-CD1 3.7Å
188	T	98.7	Very high	98	Very high	20 Å²	20	46.4 Å²	46.4	12%	0.123	22%	0.22	C	C	.	.	H	α-helix	trans	-54.9	-49	174.4	-65.6	0	0	0	0	111.6	I184 H190 L191 E192 H255	I184-T188 WeakPolarHBondContact O-CB 3.27Å; I184-T188 PolarHBondContact O-N 2.97Å; I184-T188 PolarHBondContact O-OG1 3.16Å; T188-H190 VanDerWaalsContact C-N 3.28Å; T188-H190 PolarHBondContact O-N 2.88Å; T188-L191 PolarHBondContact O-N 2.94Å; T188-L191 VanDerWaalsContact O-N 3.17Å; T188-E192 HydrophobicContact CG2-CG 4.41Å; T188-E192 WeakPolarHBondContact O-CG 3.49Å; T188-E192 PolarHBondContact O-N 2.9Å; T188-H255 WeakPolarHBondContact CG2-CE1 3.33Å
189	N	98.4	Very high	97.9	Very high	76 Å²	76	49.8 Å²	49.8	41%	0.406	24%	0.236	S	C	.	.	H	α-helix	trans	-60.6	-37.5	178.7	-70.5	-23.5	0	0	0	112.6	K185 K186 I187 R193	K185-N189 WeakPolarHBondContact O-CB 3.45Å; K185-N189 PolarHBondContact O-N 3.32Å; K185-N189 PolarHBondContact O-ND2 2.91Å; K186-N189 PolarHBondContact O-N 3.2Å; I187-N189 VanDerWaalsContact C-N 3.35Å; I187-N189 PolarHBondContact O-N 3.04Å; N189-R193 PolarHBondContact O-N 3.49Å
190	H	98.4	Very high	97.8	Very high	15 Å²	15	53.9 Å²	53.9	7%	0.069	27%	0.27	C	S	.	.	H	α-helix	trans	-65.1	-48.8	174.5	173.4	95.3	0	0	0	111	L148 K186 I187 T188 E192 R193 V194	L148-H190 HydrophobicContact CD1-CB 4.03Å; K186-H190 PolarHBondContact O-N 3.38Å; K186-H190 VanDerWaalsContact O-N 3.11Å; I187-H190 WeakPolarHBondContact O-CB 3.41Å; I187-H190 PolarHBondContact O-N 3.32Å; I187-H190 VanDerWaalsContact O-N 3.14Å; T188-H190 VanDerWaalsContact C-N 3.28Å; T188-H190 PolarHBondContact O-N 2.88Å; H190-E192 VanDerWaalsContact C-N 3.35Å; H190-E192 PolarHBondContact O-N 2.92Å; H190-R193 VanDerWaalsContact O-CB 3.31Å; H190-R193 WeakPolarHBondContact O-CB 3.46Å; H190-R193 PolarHBondContact O-N 3.44Å; H190-R193 VanDerWaalsContact O-N 3.08Å; H190-V194 WeakPolarHBondContact NE2-CG2 3.22Å; H190-V194 WeakPolarHBondContact O-CG2 3.4Å; H190-V194 PolarHBondContact O-N 3.3Å
191	L	98.5	Very high	97.6	Very high	1 Å²	1	53.6 Å²	53.6	1%	0.005	27%	0.273	C	S	.	.	H	α-helix	trans	-63.6	-37.1	-178.9	-69.6	174.6	0	0	0	113.1	I187 T188 R193 V194 S195 Y217 L251 F252 H255 V256	I187-L191 HydrophobicContact CG2-CD1 3.8Å; I187-L191 HydrophobicContact CG2-CG 4.22Å; I187-L191 WeakPolarHBondContact O-CG 3.35Å; I187-L191 PolarHBondContact O-N 2.9Å; T188-L191 PolarHBondContact O-N 2.94Å; T188-L191 VanDerWaalsContact O-N 3.17Å; L191-R193 VanDerWaalsContact C-N 3.27Å; L191-R193 PolarHBondContact O-N 3.32Å; L191-V194 PolarHBondContact O-N 3.43Å; L191-S195 WeakPolarHBondContact O-CB 3.31Å; L191-S195 PolarHBondContact O-N 3.26Å; L191-Y217 HydrophobicContact CD1-CE2 4.18Å; L191-Y217 HydrophobicContact CD2-CD2 3.76Å; L191-Y217 HydrophobicContact CD2-CE2 3.77Å; L191-Y217 HydrophobicContact CD2-CG 4.27Å; L191-Y217 HydrophobicContact CG-CE2 4.23Å; L191-L251 HydrophobicContact CD1-CB 3.67Å; L191-F252 HydrophobicContact CD1-CB 4.43Å; L191-F252 HydrophobicContact CD2-CB 4.49Å; L191-F252 HydrophobicContact CD2-CD2 3.57Å; L191-F252 HydrophobicContact CD2-CE2 4.24Å; L191-F252 HydrophobicContact CD2-CG 4.42Å; L191-H255 HydrophobicContact CB-CB 4.01Å; L191-V256 HydrophobicContact CB-CG2 3.91Å; L191-V256 HydrophobicContact CD2-CG2 3.89Å; L191-V256 HydrophobicContact CG-CG2 4.44Å
192	E	98.4	Very high	97.3	Very high	69 Å²	69	53.8 Å²	53.8	32%	0.322	27%	0.273	S	S	.	.	H	α-helix	trans	-63.4	-34.6	173.6	-73.9	-174.7	168.5	0	0	112.6	T188 H190 K196 H255	T188-E192 HydrophobicContact CG2-CG 4.41Å; T188-E192 WeakPolarHBondContact O-CG 3.49Å; T188-E192 PolarHBondContact O-N 2.9Å; H190-E192 VanDerWaalsContact C-N 3.35Å; H190-E192 PolarHBondContact O-N 2.92Å; E192-K196 VanDerWaalsContact O-CG 3.32Å; E192-K196 WeakPolarHBondContact O-CG 3.24Å; E192-K196 PolarHBondContact O-N 3.06Å; E192-K196 VanDerWaalsContact O-N 3.15Å; E192-H255 IonicContact OE1-CE1 2.85Å; E192-H255 IonicContact OE1-ND1 2.77Å
193	R	98	Very high	96.8	Very high	115 Å²	115	56.8 Å²	56.8	43%	0.434	29%	0.294	S	S	.	.	H	α-helix	trans	-68.1	-47.9	173.8	-164.6	-168.6	-49.9	104.1	4.9	110.8	N189 H190 L191 S195 K196 E197	N189-R193 PolarHBondContact O-N 3.49Å; H190-R193 VanDerWaalsContact O-CB 3.31Å; H190-R193 WeakPolarHBondContact O-CB 3.46Å; H190-R193 PolarHBondContact O-N 3.44Å; H190-R193 VanDerWaalsContact O-N 3.08Å; L191-R193 VanDerWaalsContact C-N 3.27Å; L191-R193 PolarHBondContact O-N 3.32Å; R193-S195 VanDerWaalsContact C-N 3.28Å; R193-S195 PolarHBondContact O-N 3.11Å; R193-K196 WeakPolarHBondContact O-CB 3.45Å; R193-K196 PolarHBondContact O-N 2.88Å; R193-K196 VanDerWaalsContact O-N 3.09Å; R193-E197 WeakPolarHBondContact CD-OE1 3.14Å; R193-E197 WeakPolarHBondContact CG-OE1 3.23Å; R193-E197 WeakPolarHBondContact O-CG 3.36Å; R193-E197 PolarHBondContact O-N 3.45Å
194	V	97.9	Very high	96.4	Very high	21 Å²	21	63.8 Å²	63.8	13%	0.127	33%	0.331	C	S	.	.	H	α-helix	trans	-56	-44.4	175.9	171.7	0	0	0	0	110.9	H190 L191 K196 E197 L198 A213	H190-V194 WeakPolarHBondContact NE2-CG2 3.22Å; H190-V194 WeakPolarHBondContact O-CG2 3.4Å; H190-V194 PolarHBondContact O-N 3.3Å; L191-V194 PolarHBondContact O-N 3.43Å; V194-K196 PolarHBondContact O-N 3.06Å; V194-E197 PolarHBondContact O-N 2.95Å; V194-L198 HydrophobicContact CG1-CD1 4.03Å; V194-L198 HydrophobicContact CG1-CG 4.43Å; V194-L198 WeakPolarHBondContact O-CB 3.34Å; V194-L198 WeakPolarHBondContact O-CG 3.29Å; V194-L198 PolarHBondContact O-N 3.4Å; V194-A213 HydrophobicContact CG1-CB 3.77Å
195	S	97.9	Very high	96.1	Very high	7 Å²	7	65.7 Å²	65.7	5%	0.049	34%	0.341	C	S	.	.	H	α-helix	trans	-61.7	-40.9	177	179.2	0	0	0	0	112.6	L191 R193 L198 Q199 H255 H260	L191-S195 WeakPolarHBondContact O-CB 3.31Å; L191-S195 PolarHBondContact O-N 3.26Å; R193-S195 VanDerWaalsContact C-N 3.28Å; R193-S195 PolarHBondContact O-N 3.11Å; S195-L198 PolarHBondContact O-N 3.32Å; S195-Q199 WeakPolarHBondContact O-CB 3.4Å; S195-Q199 PolarHBondContact O-N 3.46Å; S195-H255 WeakPolarHBondContact CB-O 3.47Å; S195-H255 PolarHBondContact OG-O 3.15Å; S195-H260 WeakPolarHBondContact CA-NE2 3.1Å; S195-H260 PolarHBondContact O-CE1 2.89Å; S195-H260 VanDerWaalsContact O-CE1 3.3Å; S195-H260 PolarHBondContact O-NE2 3.41Å; S195-H260 PolarHBondContact OG-NE2 3.36Å
196	K	97.8	Very high	96	Very high	138 Å²	138	60.2 Å²	60.2	60%	0.6	32%	0.317	S	S	*	.	H	α-helix	trans	-65.3	-41.3	175.4	-71.9	169.6	-175.5	172.4	0	112.2	E192 R193 V194 Q199 A200	E192-K196 VanDerWaalsContact O-CG 3.32Å; E192-K196 WeakPolarHBondContact O-CG 3.24Å; E192-K196 PolarHBondContact O-N 3.06Å; E192-K196 VanDerWaalsContact O-N 3.15Å; R193-K196 WeakPolarHBondContact O-CB 3.45Å; R193-K196 PolarHBondContact O-N 2.88Å; R193-K196 VanDerWaalsContact O-N 3.09Å; V194-K196 PolarHBondContact O-N 3.06Å; K196-Q199 PolarHBondContact O-N 2.91Å; K196-A200 PolarHBondContact O-N 3.41Å
197	E	96.3	Very high	95.9	Very high	114 Å²	114	59.2 Å²	59.2	53%	0.533	31%	0.313	S	S	.	.	H	α-helix	trans	-65.1	-40.9	177	-70.9	170.5	-165.7	0	0	111.7	R193 V194 A200 S201	R193-E197 WeakPolarHBondContact CD-OE1 3.14Å; R193-E197 WeakPolarHBondContact CG-OE1 3.23Å; R193-E197 WeakPolarHBondContact O-CG 3.36Å; R193-E197 PolarHBondContact O-N 3.45Å; V194-E197 PolarHBondContact O-N 2.95Å; E197-A200 PolarHBondContact O-N 3.46Å; E197-S201 PolarHBondContact O-N 3.45Å; E197-S201 PolarHBondContact O-OG 2.84Å
198	L	97	Very high	95.7	Very high	6 Å²	6	64.4 Å²	64.4	3%	0.031	34%	0.338	C	S	.	.	H	α-helix	trans	-62.5	-43.9	172.5	-73.5	171.6	0	0	0	111.4	V194 S195 A200 S201 Y206 R209 F210 A213 V256	V194-L198 HydrophobicContact CG1-CD1 4.03Å; V194-L198 HydrophobicContact CG1-CG 4.43Å; V194-L198 WeakPolarHBondContact O-CB 3.34Å; V194-L198 WeakPolarHBondContact O-CG 3.29Å; V194-L198 PolarHBondContact O-N 3.4Å; S195-L198 PolarHBondContact O-N 3.32Å; L198-A200 PolarHBondContact O-N 3.22Å; L198-S201 VanDerWaalsContact O-CB 3.22Å; L198-S201 WeakPolarHBondContact O-CB 3.41Å; L198-S201 PolarHBondContact O-N 2.87Å; L198-S201 PolarHBondContact O-OG 3.38Å; L198-Y206 WeakPolarHBondContact O-CE2 3.13Å; L198-R209 HydrophobicContact CD2-CB 3.77Å; L198-F210 HydrophobicContact CD1-CD2 4.11Å; L198-F210 HydrophobicContact CD2-CB 4.36Å; L198-A213 HydrophobicContact CD1-CB 4.19Å; L198-V256 HydrophobicContact CD1-CG1 3.76Å
199	Q	95	Very high	95.6	Very high	147 Å²	147	69.6 Å²	69.6	69%	0.687	36%	0.355	S	S	*	.	H	α-helix	trans	-62.5	-31.7	178	-166	171.7	27.6	0	0	113	S195 K196 S201	S195-Q199 WeakPolarHBondContact O-CB 3.4Å; S195-Q199 PolarHBondContact O-N 3.46Å; K196-Q199 PolarHBondContact O-N 2.91Å; Q199-S201 VanDerWaalsContact C-N 3.29Å
200	A	94.9	Very high	95.6	Very high	86 Å²	86	66 Å²	66	71%	0.711	34%	0.336	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.3	-4.3	176	0	0	0	0	0	113.7	K196 E197 L198	K196-A200 PolarHBondContact O-N 3.41Å; E197-A200 PolarHBondContact O-N 3.46Å; L198-A200 PolarHBondContact O-N 3.22Å
201	S	94	Very high	95.5	Very high	26 Å²	26	66.4 Å²	66.4	18%	0.182	34%	0.338	C	S	.	.	S	Bend	trans	-75.8	144.8	-176.7	-66.2	0	0	0	0	111.9	E197 L198 Q199	E197-S201 PolarHBondContact O-N 3.45Å; E197-S201 PolarHBondContact O-OG 2.84Å; L198-S201 VanDerWaalsContact O-CB 3.22Å; L198-S201 WeakPolarHBondContact O-CB 3.41Å; L198-S201 PolarHBondContact O-N 2.87Å; L198-S201 PolarHBondContact O-OG 3.38Å; Q199-S201 VanDerWaalsContact C-N 3.29Å
202	P	92.1	Very high	95.3	Very high	66 Å²	66	70 Å²	70	43%	0.429	36%	0.357	S	S	.	.			trans	-66.9	148.2	176.6	28.3	-33.7	0	0	0	110.9	D204 L205 Y206	P202-D204 VanDerWaalsContact C-N 3.26Å; P202-D204 PolarHBondContact O-N 3.31Å; P202-L205 HydrophobicContact CG-CB 4.14Å; P202-L205 HydrophobicContact CG-CD1 4.04Å; P202-L205 HydrophobicContact CG-CG 4.19Å; P202-L205 PolarHBondContact O-N 2.89Å; P202-Y206 PolarHBondContact O-N 3.47Å; P202-Y206 VanDerWaalsContact O-N 3.15Å
203	P	88.2	Confident	95.2	Very high	91 Å²	91	67.4 Å²	67.4	59%	0.591	35%	0.347	S	S	*	.	H	α-helix	trans	-53.9	-40	-178	-27.2	35	0	0	0	113.8	L205 Y206	P203-L205 VanDerWaalsContact C-N 3.26Å; P203-L205 PolarHBondContact O-N 2.97Å; P203-Y206 VanDerWaalsContact O-CB 3.26Å; P203-Y206 WeakPolarHBondContact O-CB 3.45Å; P203-Y206 PolarHBondContact O-N 3.41Å; P203-Y206 VanDerWaalsContact O-N 3.15Å
204	D	88.6	Confident	95.2	Very high	147 Å²	147	62.1 Å²	62.1	79%	0.786	33%	0.328	S	S	*	.	H	α-helix	trans	-64.8	-27.9	-175.8	-57.5	-24.5	0	0	0	113.6	P202	P202-D204 VanDerWaalsContact C-N 3.26Å; P202-D204 PolarHBondContact O-N 3.31Å
205	L	92.8	Very high	95.1	Very high	69 Å²	69	62 Å²	62	36%	0.361	33%	0.331	S	S	.	.	H	α-helix	trans	-105	-1.4	179.1	-59.4	179.2	0	0	0	112.4	P202 P203 I207 E208 R209	P202-L205 HydrophobicContact CG-CB 4.14Å; P202-L205 HydrophobicContact CG-CD1 4.04Å; P202-L205 HydrophobicContact CG-CG 4.19Å; P202-L205 PolarHBondContact O-N 2.89Å; P203-L205 VanDerWaalsContact C-N 3.26Å; P203-L205 PolarHBondContact O-N 2.97Å; L205-I207 PolarHBondContact O-N 3.46Å; L205-E208 PolarHBondContact O-N 2.91Å; L205-R209 HydrophobicContact CB-CG 4.31Å; L205-R209 WeakPolarHBondContact O-CB 3.36Å; L205-R209 VanDerWaalsContact O-CG 3.27Å; L205-R209 WeakPolarHBondContact O-CG 3.45Å; L205-R209 PolarHBondContact O-N 3.26Å
206	Y	95.7	Very high	95	Very high	16 Å²	16	64.2 Å²	64.2	6%	0.063	34%	0.34	C	S	.	.	H	α-helix	trans	-61.7	-45.4	-168.3	-169.4	-90.8	0	0	0	112.4	L198 P202 P203 E208 R209 F210 H260 S263 L264 L267	L198-Y206 WeakPolarHBondContact O-CE2 3.13Å; P202-Y206 PolarHBondContact O-N 3.47Å; P202-Y206 VanDerWaalsContact O-N 3.15Å; P203-Y206 VanDerWaalsContact O-CB 3.26Å; P203-Y206 WeakPolarHBondContact O-CB 3.45Å; P203-Y206 PolarHBondContact O-N 3.41Å; P203-Y206 VanDerWaalsContact O-N 3.15Å; Y206-E208 VanDerWaalsContact C-N 3.34Å; Y206-E208 PolarHBondContact O-N 3.15Å; Y206-R209 PolarHBondContact O-N 2.82Å; Y206-F210 WeakPolarHBondContact O-CB 3.45Å; Y206-F210 PolarHBondContact O-N 2.9Å; Y206-H260 WeakPolarHBondContact OH-CB 3.32Å; Y206-H260 VanDerWaalsContact OH-CG 3.29Å; Y206-H260 PolarHBondContact OH-ND1 3.46Å; Y206-S263 PolarHBondContact OH-OG 3.23Å; Y206-L264 HydrophobicContact CD1-CD1 4.12Å; Y206-L264 HydrophobicContact CE1-CB 4.28Å; Y206-L264 HydrophobicContact CE1-CD1 4.16Å; Y206-L267 HydrophobicContact CD1-CD1 3.81Å; Y206-L267 HydrophobicContact CG-CD1 4.19Å
207	I	96.1	Very high	94.9	Very high	14 Å²	14	57.9 Å²	57.9	7%	0.072	31%	0.313	C	S	.	.	H	α-helix	trans	-59.7	-46.2	178.1	-63.8	175.9	0	0	0	110.6	L205 F210 N211 L264 L267 L268 A271 V278 T282 I286	L205-I207 PolarHBondContact O-N 3.46Å; I207-F210 PolarHBondContact O-N 3.39Å; I207-N211 WeakPolarHBondContact O-CB 3.34Å; I207-N211 PolarHBondContact O-N 3.39Å; I207-L264 HydrophobicContact CG1-CD1 4.26Å; I207-L267 HydrophobicContact CD1-CB 3.98Å; I207-L267 HydrophobicContact CG1-CB 4.1Å; I207-L268 HydrophobicContact CD1-CD2 4.24Å; I207-L268 HydrophobicContact CG1-CD2 4.3Å; I207-L268 HydrophobicContact CG2-CD2 3.93Å; I207-A271 HydrophobicContact CD1-CB 3.85Å; I207-V278 HydrophobicContact CB-CG2 4.49Å; I207-V278 HydrophobicContact CD1-CG2 3.79Å; I207-V278 HydrophobicContact CG2-CG1 4.16Å; I207-V278 HydrophobicContact CG2-CG2 4.05Å; I207-T282 HydrophobicContact CG2-CG2 4.22Å; I207-I286 HydrophobicContact CG2-CD1 3.4Å
208	E	95.1	Very high	94.9	Very high	109 Å²	109	53.8 Å²	53.8	51%	0.509	29%	0.294	S	S	.	.	H	α-helix	trans	-66.8	-44.3	-178.9	-173	177	-165.6	0	0	111.5	L205 Y206 F210 N211 I212	L205-E208 PolarHBondContact O-N 2.91Å; Y206-E208 VanDerWaalsContact C-N 3.34Å; Y206-E208 PolarHBondContact O-N 3.15Å; E208-F210 VanDerWaalsContact C-N 3.35Å; E208-F210 PolarHBondContact O-N 3.15Å; E208-N211 WeakPolarHBondContact O-CB 3.26Å; E208-N211 PolarHBondContact O-N 3.15Å; E208-I212 HydrophobicContact CG-CD1 4.16Å; E208-I212 WeakPolarHBondContact O-CG1 3.47Å; E208-I212 PolarHBondContact O-N 2.72Å
209	R	96.3	Very high	94.7	Very high	128 Å²	128	54.6 Å²	54.6	48%	0.483	30%	0.304	S	S	.	.	H	α-helix	trans	-62.4	-42	176.9	-68.5	-70	-179.4	-178.5	-1.2	111.9	L198 L205 Y206 I212 A213	L198-R209 HydrophobicContact CD2-CB 3.77Å; L205-R209 HydrophobicContact CB-CG 4.31Å; L205-R209 WeakPolarHBondContact O-CB 3.36Å; L205-R209 VanDerWaalsContact O-CG 3.27Å; L205-R209 WeakPolarHBondContact O-CG 3.45Å; L205-R209 PolarHBondContact O-N 3.26Å; Y206-R209 PolarHBondContact O-N 2.82Å; R209-I212 PolarHBondContact O-N 2.81Å; R209-A213 WeakPolarHBondContact O-CB 3.47Å; R209-A213 PolarHBondContact O-N 2.91Å
210	F	97.7	Very high	94.8	Very high	1 Å²	1	47.8 Å²	47.8	0%	0.004	27%	0.272	C	S	.	.	H	α-helix	trans	-62.4	-44.6	174.6	-175.2	-88.6	0	0	0	111.4	L198 Y206 I207 E208 I212 A213 L214 F252 V256 A257 H260 L264 I286 L290	L198-F210 HydrophobicContact CD1-CD2 4.11Å; L198-F210 HydrophobicContact CD2-CB 4.36Å; Y206-F210 WeakPolarHBondContact O-CB 3.45Å; Y206-F210 PolarHBondContact O-N 2.9Å; I207-F210 PolarHBondContact O-N 3.39Å; E208-F210 VanDerWaalsContact C-N 3.35Å; E208-F210 PolarHBondContact O-N 3.15Å; F210-I212 PolarHBondContact O-N 2.67Å; F210-A213 PolarHBondContact O-N 3.18Å; F210-L214 HydrophobicContact CE1-CB 4.43Å; F210-L214 HydrophobicContact CE1-CD2 4.03Å; F210-L214 VanDerWaalsContact O-CB 3.29Å; F210-L214 WeakPolarHBondContact O-CB 3.21Å; F210-L214 PolarHBondContact O-N 3.21Å; F210-F252 HydrophobicContact CZ-CE1 4.45Å; F210-V256 HydrophobicContact CE2-CG1 4.4Å; F210-A257 HydrophobicContact CZ-CB 4.47Å; F210-H260 HydrophobicContact CD2-CB 4.34Å; F210-H260 HydrophobicContact CE2-CB 4.12Å; F210-L264 HydrophobicContact CB-CD1 4.36Å; F210-L264 HydrophobicContact CD1-CD1 4.45Å; F210-L264 HydrophobicContact CD1-CD2 3.52Å; F210-L264 HydrophobicContact CD2-CD2 4.14Å; F210-L264 HydrophobicContact CE1-CD2 3.47Å; F210-L264 VanDerWaalsContact CE1-CD2 3.47Å; F210-L264 HydrophobicContact CE2-CD2 4.11Å; F210-L264 HydrophobicContact CG-CD1 4.34Å; F210-L264 HydrophobicContact CG-CD2 3.86Å; F210-L264 HydrophobicContact CZ-CD2 3.79Å; F210-I286 HydrophobicContact CD1-CG1 4.48Å; F210-I286 HydrophobicContact CD1-CG2 4.39Å; F210-I286 HydrophobicContact CE1-CG2 4.35Å; F210-L290 HydrophobicContact CE1-CD2 4.15Å; F210-L290 HydrophobicContact CZ-CD2 4.1Å
211	N	96.4	Very high	94.8	Very high	24 Å²	24	44 Å²	44	13%	0.128	24%	0.24	C	C	.	.	H	α-helix	trans	-60.3	-43.3	176.8	-178.7	56.7	0	0	0	112.5	I207 E208 L214 G215 T282 N285 I286	I207-N211 WeakPolarHBondContact O-CB 3.34Å; I207-N211 PolarHBondContact O-N 3.39Å; E208-N211 WeakPolarHBondContact O-CB 3.26Å; E208-N211 PolarHBondContact O-N 3.15Å; N211-L214 PolarHBondContact O-N 3.24Å; N211-G215 PolarHBondContact O-N 2.8Å; N211-T282 HydrophobicContact CB-CG2 3.9Å; N211-N285 VanDerWaalsContact OD1-CB 3.3Å; N211-N285 WeakPolarHBondContact OD1-CB 3.39Å; N211-I286 HydrophobicContact CB-CD1 3.94Å; N211-I286 HydrophobicContact CB-CG1 3.76Å
212	I	95.4	Very high	94.8	Very high	76 Å²	76	48.5 Å²	48.5	39%	0.39	26%	0.258	S	S	.	.	H	α-helix	trans	-60.9	-50.8	176.1	-68.7	165.6	0	0	0	109.9	E208 R209 F210 L214 G215 Q216	E208-I212 HydrophobicContact CG-CD1 4.16Å; E208-I212 WeakPolarHBondContact O-CG1 3.47Å; E208-I212 PolarHBondContact O-N 2.72Å; R209-I212 PolarHBondContact O-N 2.81Å; F210-I212 PolarHBondContact O-N 2.67Å; I212-L214 VanDerWaalsContact C-N 3.33Å; I212-L214 PolarHBondContact O-N 3.23Å; I212-G215 PolarHBondContact O-N 3.31Å; I212-Q216 WeakPolarHBondContact O-CB 3.27Å; I212-Q216 PolarHBondContact O-N 3.36Å
213	A	96.9	Very high	94.9	Very high	14 Å²	14	46.6 Å²	46.6	12%	0.116	25%	0.247	C	C	.	.	H	α-helix	trans	-59	-43.8	179.9	0	0	0	0	0	112.3	V194 L198 R209 F210 Y217	V194-A213 HydrophobicContact CG1-CB 3.77Å; L198-A213 HydrophobicContact CD1-CB 4.19Å; R209-A213 WeakPolarHBondContact O-CB 3.47Å; R209-A213 PolarHBondContact O-N 2.91Å; F210-A213 PolarHBondContact O-N 3.18Å; A213-Y217 WeakPolarHBondContact O-CB 3.07Å; A213-Y217 PolarHBondContact O-N 3.44Å
214	L	97.3	Very high	95.3	Very high	5 Å²	5	42.3 Å²	42.3	3%	0.026	22%	0.219	C	C	.	.	H	α-helix	trans	-63.4	-51	176.9	176.9	62.4	0	0	0	111.7	F210 N211 I212 Y217 M218 F252 L293	F210-L214 HydrophobicContact CE1-CB 4.43Å; F210-L214 HydrophobicContact CE1-CD2 4.03Å; F210-L214 VanDerWaalsContact O-CB 3.29Å; F210-L214 WeakPolarHBondContact O-CB 3.21Å; F210-L214 PolarHBondContact O-N 3.21Å; N211-L214 PolarHBondContact O-N 3.24Å; I212-L214 VanDerWaalsContact C-N 3.33Å; I212-L214 PolarHBondContact O-N 3.23Å; L214-Y217 PolarHBondContact O-N 2.96Å; L214-M218 HydrophobicContact CD1-CE 3.85Å; L214-M218 HydrophobicContact CD1-CG 4.09Å; L214-M218 WeakPolarHBondContact O-CB 3.09Å; L214-M218 VanDerWaalsContact O-CG 3.24Å; L214-M218 WeakPolarHBondContact O-CG 3.37Å; L214-M218 PolarHBondContact O-N 2.9Å; L214-F252 HydrophobicContact CB-CZ 4.1Å; L214-F252 HydrophobicContact CD1-CD1 4.3Å; L214-F252 HydrophobicContact CD1-CE1 3.7Å; L214-F252 HydrophobicContact CD1-CZ 3.98Å; L214-L293 HydrophobicContact CD1-CD1 3.86Å
215	G	95	Very high	95.7	Very high	19 Å²	19	36.3 Å²	36.3	20%	0.196	19%	0.187	C	C	.	.	H	α-helix	trans	-64.2	-41.2	-179.3	0	0	0	0	0	112.7	N211 I212 G219	N211-G215 PolarHBondContact O-N 2.8Å; I212-G215 PolarHBondContact O-N 3.31Å; G215-G219 PolarHBondContact O-N 3.37Å
216	Q	95.4	Very high	95.9	Very high	53 Å²	53	36.5 Å²	36.5	25%	0.248	19%	0.193	C	C	.	.	H	α-helix	trans	-62.4	-46.8	176.4	-179.4	170.9	-12.2	0	0	111.3	L148 T149 I212 G219 A220	L148-Q216 PolarHBondContact O-NE2 3.24Å; T149-Q216 VanDerWaalsContact C-NE2 3.34Å; T149-Q216 VanDerWaalsContact CA-NE2 3.3Å; T149-Q216 PolarHBondContact O-NE2 3.44Å; I212-Q216 WeakPolarHBondContact O-CB 3.27Å; I212-Q216 PolarHBondContact O-N 3.36Å; Q216-G219 PolarHBondContact O-N 3.47Å; Q216-A220 WeakPolarHBondContact O-CB 3.27Å; Q216-A220 PolarHBondContact O-N 3.36Å
217	Y	97.5	Very high	96	Very high	5 Å²	5	36 Å²	36	2%	0.02	19%	0.191	C	C	.	.	H	α-helix	trans	-64.9	-48.3	178	-173.2	-105.2	0	0	0	112.2	L148 I187 L191 A213 L214 G219 A220 L221 L248 F252	L148-Y217 HydrophobicContact CD2-CD2 3.85Å; L148-Y217 HydrophobicContact CD2-CE2 3.88Å; I187-Y217 HydrophobicContact CG2-CE2 3.87Å; I187-Y217 WeakPolarHBondContact CG2-OH 3.39Å; L191-Y217 HydrophobicContact CD1-CE2 4.18Å; L191-Y217 HydrophobicContact CD2-CD2 3.76Å; L191-Y217 HydrophobicContact CD2-CE2 3.77Å; L191-Y217 HydrophobicContact CD2-CG 4.27Å; L191-Y217 HydrophobicContact CG-CE2 4.23Å; A213-Y217 WeakPolarHBondContact O-CB 3.07Å; A213-Y217 PolarHBondContact O-N 3.44Å; L214-Y217 PolarHBondContact O-N 2.96Å; Y217-G219 VanDerWaalsContact C-N 3.28Å; Y217-G219 PolarHBondContact O-N 3Å; Y217-A220 WeakPolarHBondContact O-CB 3.42Å; Y217-A220 PolarHBondContact O-N 3.46Å; Y217-A220 VanDerWaalsContact O-N 3.13Å; Y217-L221 HydrophobicContact CD1-CD1 4.21Å; Y217-L221 HydrophobicContact CD1-CG 4.26Å; Y217-L221 HydrophobicContact CE1-CD1 3.71Å; Y217-L221 HydrophobicContact CE1-CD2 4.01Å; Y217-L221 HydrophobicContact CE1-CG 3.93Å; Y217-L221 HydrophobicContact CE2-CD2 4.27Å; Y217-L221 WeakPolarHBondContact O-CG 3.32Å; Y217-L221 PolarHBondContact O-N 3.37Å; Y217-L248 PolarHBondContact OH-O 3.33Å; Y217-F252 HydrophobicContact CD1-CB 3.64Å; Y217-F252 AromaticContact CD1-CD2 3.35Å; Y217-F252 HydrophobicContact CD1-CD2 3.35Å; Y217-F252 HydrophobicContact CD1-CE2 4.26Å; Y217-F252 AromaticContact CD1-CG 3.74Å; Y217-F252 HydrophobicContact CD1-CG 3.74Å; Y217-F252 HydrophobicContact CD2-CD2 4.24Å; Y217-F252 HydrophobicContact CE1-CB 3.44Å; Y217-F252 VanDerWaalsContact CE1-CB 3.44Å; Y217-F252 AromaticContact CE1-CD2 4Å; Y217-F252 HydrophobicContact CE1-CD2 4Å; Y217-F252 HydrophobicContact CE1-CG 4.1Å; Y217-F252 AromaticContact CG-CD2 3.48Å; Y217-F252 HydrophobicContact CG-CD2 3.48Å; Y217-F252 VanDerWaalsContact CG-CD2 3.48Å; Y217-F252 HydrophobicContact CG-CE2 4.1Å; Y217-F252 HydrophobicContact CG-CG 4.33Å
218	M	95.4	Very high	96.1	Very high	28 Å²	28	35.5 Å²	35.5	14%	0.138	19%	0.188	C	C	.	.	H	α-helix	trans	-61.9	-36.8	178.9	-68.8	-62.6	177.2	0	0	112.3	L214 L221 L293	L214-M218 HydrophobicContact CD1-CE 3.85Å; L214-M218 HydrophobicContact CD1-CG 4.09Å; L214-M218 WeakPolarHBondContact O-CB 3.09Å; L214-M218 VanDerWaalsContact O-CG 3.24Å; L214-M218 WeakPolarHBondContact O-CG 3.37Å; L214-M218 PolarHBondContact O-N 2.9Å; M218-L221 HydrophobicContact SD-CD1 4.41Å; M218-L293 HydrophobicContact CE-CD1 4.5Å; M218-L293 HydrophobicContact CE-CD2 3.47Å; M218-L293 VanDerWaalsContact CE-CD2 3.47Å; M218-L293 HydrophobicContact CE-CG 3.84Å
219	G	93.7	Very high	96.2	Very high	23 Å²	23	33.1 Å²	33.1	24%	0.237	18%	0.178	C	C	.	.	H	α-helix	trans	-63.6	-46.9	171.7	0	0	0	0	0	112.2	G215 Q216 Y217 L221 Q222	G215-G219 PolarHBondContact O-N 3.37Å; Q216-G219 PolarHBondContact O-N 3.47Å; Y217-G219 VanDerWaalsContact C-N 3.28Å; Y217-G219 PolarHBondContact O-N 3Å; G219-L221 VanDerWaalsContact C-N 3.26Å; G219-L221 PolarHBondContact O-N 2.87Å; G219-Q222 VanDerWaalsContact O-CB 3.31Å; G219-Q222 WeakPolarHBondContact O-CB 3.42Å; G219-Q222 PolarHBondContact O-N 3.28Å
220	A	95.4	Very high	96.3	Very high	4 Å²	4	29 Å²	29	3%	0.033	16%	0.163	C	C	.	.	H	α-helix	trans	-59.1	-37	177.9	0	0	0	0	0	112.4	L147 L148 Q216 Y217 Q222 S223 I224	L147-A220 VanDerWaalsContact O-CB 3.25Å; L147-A220 WeakPolarHBondContact O-CB 3.28Å; L148-A220 HydrophobicContact CD2-CB 4.06Å; Q216-A220 WeakPolarHBondContact O-CB 3.27Å; Q216-A220 PolarHBondContact O-N 3.36Å; Y217-A220 WeakPolarHBondContact O-CB 3.42Å; Y217-A220 PolarHBondContact O-N 3.46Å; Y217-A220 VanDerWaalsContact O-N 3.13Å; A220-Q222 PolarHBondContact O-N 2.88Å; A220-S223 PolarHBondContact O-N 3.06Å; A220-I224 HydrophobicContact CB-CD1 4.27Å; A220-I224 WeakPolarHBondContact O-CG1 3.5Å; A220-I224 PolarHBondContact O-N 3.14Å
221	L	96.3	Very high	96.3	Very high	6 Å²	6	28.9 Å²	28.9	3%	0.031	16%	0.163	C	C	.	.	H	α-helix	trans	-60.9	-31.3	176.7	-65.6	-167.2	0	0	0	113.1	Y217 M218 G219 S223 I224 V225 L248 I249	Y217-L221 HydrophobicContact CD1-CD1 4.21Å; Y217-L221 HydrophobicContact CD1-CG 4.26Å; Y217-L221 HydrophobicContact CE1-CD1 3.71Å; Y217-L221 HydrophobicContact CE1-CD2 4.01Å; Y217-L221 HydrophobicContact CE1-CG 3.93Å; Y217-L221 HydrophobicContact CE2-CD2 4.27Å; Y217-L221 WeakPolarHBondContact O-CG 3.32Å; Y217-L221 PolarHBondContact O-N 3.37Å; M218-L221 HydrophobicContact SD-CD1 4.41Å; G219-L221 VanDerWaalsContact C-N 3.26Å; G219-L221 PolarHBondContact O-N 2.87Å; L221-S223 PolarHBondContact O-N 2.65Å; L221-I224 PolarHBondContact O-N 3.25Å; L221-V225 WeakPolarHBondContact O-CB 3.4Å; L221-V225 WeakPolarHBondContact O-CG2 3.41Å; L221-V225 PolarHBondContact O-N 3.43Å; L221-V225 VanDerWaalsContact O-N 3.08Å; L221-L248 HydrophobicContact CD1-CB 4.2Å; L221-L248 HydrophobicContact CD2-CB 3.73Å; L221-L248 HydrophobicContact CD2-CD1 3.69Å; L221-L248 HydrophobicContact CD2-CG 4.32Å; L221-I249 HydrophobicContact CD1-CG1 3.88Å
222	Q	93.8	Very high	96.4	Very high	121 Å²	121	27.9 Å²	27.9	57%	0.565	16%	0.157	S	C	*	.	H	α-helix	trans	-61.8	-27.2	176.1	-59	-57.2	-46.6	0	0	112.3	G219 A220 P226	G219-Q222 VanDerWaalsContact O-CB 3.31Å; G219-Q222 WeakPolarHBondContact O-CB 3.42Å; G219-Q222 PolarHBondContact O-N 3.28Å; A220-Q222 PolarHBondContact O-N 2.88Å; Q222-P226 WeakPolarHBondContact O-CD 3.42Å; Q222-P226 WeakPolarHBondContact O-CG 3.16Å
223	S	93.8	Very high	96.5	Very high	26 Å²	26	28.9 Å²	28.9	18%	0.182	16%	0.159	C	C	.	.	H	α-helix	trans	-96.2	-40.1	178.4	-62.6	0	0	0	0	112.5	Y160 A220 L221 L227	Y160-S223 PolarHBondContact OH-OG 3.48Å; A220-S223 PolarHBondContact O-N 3.06Å; L221-S223 PolarHBondContact O-N 2.65Å; S223-L227 WeakPolarHBondContact O-CD1 3.47Å; S223-L227 VanDerWaalsContact O-CG 3.3Å; S223-L227 WeakPolarHBondContact O-CG 3.15Å; S223-L227 PolarHBondContact O-N 2.83Å
224	I	96.8	Very high	96.4	Very high	0 Å²	0	33.4 Å²	33.4	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-66.4	-46.7	-177.6	-67.5	170.3	0	0	0	110.9	I144 L147 L148 A220 L221 L227 F228 L248	I144-I224 HydrophobicContact CG2-CD1 4.45Å; L147-I224 HydrophobicContact CB-CD1 4.35Å; L147-I224 HydrophobicContact CB-CG1 4.17Å; L147-I224 HydrophobicContact CD1-CG1 3.69Å; L148-I224 HydrophobicContact CD2-CD1 3.95Å; L148-I224 HydrophobicContact CG-CD1 4.19Å; A220-I224 HydrophobicContact CB-CD1 4.27Å; A220-I224 WeakPolarHBondContact O-CG1 3.5Å; A220-I224 PolarHBondContact O-N 3.14Å; L221-I224 PolarHBondContact O-N 3.25Å; I224-L227 PolarHBondContact O-N 2.91Å; I224-F228 HydrophobicContact CG2-CD2 4Å; I224-F228 HydrophobicContact CG2-CE2 4.36Å; I224-F228 WeakPolarHBondContact O-CD2 3.28Å; I224-F228 PolarHBondContact O-N 3.31Å; I224-F228 VanDerWaalsContact O-N 3.13Å; I224-L248 HydrophobicContact CG2-CD1 3.99Å
225	V	97.8	Very high	96.5	Very high	22 Å²	22	34 Å²	34	13%	0.133	18%	0.178	C	C	.	.	H	α-helix	trans	-60.8	-48.3	-174.8	173.1	0	0	0	0	111.9	L221 L227 F228 I229 K245 L248	L221-V225 WeakPolarHBondContact O-CB 3.4Å; L221-V225 WeakPolarHBondContact O-CG2 3.41Å; L221-V225 PolarHBondContact O-N 3.43Å; L221-V225 VanDerWaalsContact O-N 3.08Å; V225-L227 VanDerWaalsContact C-N 3.35Å; V225-L227 PolarHBondContact O-N 2.83Å; V225-F228 CarbonylContact O-C 3.58Å; V225-F228 PolarHBondContact O-N 3.32Å; V225-I229 PolarHBondContact O-N 3.23Å; V225-K245 HydrophobicContact CG1-CB 4.36Å; V225-K245 HydrophobicContact CG2-CB 4.01Å; V225-K245 HydrophobicContact CG2-CG 4.32Å; V225-L248 HydrophobicContact CG2-CD1 4.24Å
226	P	97	Very high	96.6	Very high	73 Å²	73	33 Å²	33	47%	0.474	17%	0.169	S	C	.	.	H	α-helix	trans	-62.3	-35.9	175.3	-26.2	36.8	0	0	0	114.1	Q222 F228 I229	Q222-P226 WeakPolarHBondContact O-CD 3.42Å; Q222-P226 WeakPolarHBondContact O-CG 3.16Å; P226-F228 PolarHBondContact O-N 2.96Å; P226-I229 WeakPolarHBondContact O-CB 3.37Å; P226-I229 WeakPolarHBondContact O-CG2 3.45Å; P226-I229 PolarHBondContact O-N 3.32Å
227	L	97.5	Very high	96.7	Very high	6 Å²	6	33.5 Å²	33.5	3%	0.031	17%	0.171	C	C	.	.	H	α-helix	trans	-62.8	-34.2	177	-78.2	171.8	0	0	0	112.5	L147 Y160 I163 S223 I224 V225	L147-L227 HydrophobicContact CD1-CD1 3.65Å; Y160-L227 HydrophobicContact CD1-CD1 4.05Å; Y160-L227 HydrophobicContact CD1-CD2 3.7Å; Y160-L227 HydrophobicContact CD1-CG 3.95Å; Y160-L227 HydrophobicContact CE1-CD1 4.12Å; Y160-L227 HydrophobicContact CE1-CG 4.36Å; Y160-L227 HydrophobicContact CG-CD2 4.42Å; I163-L227 HydrophobicContact CB-CD2 3.97Å; I163-L227 HydrophobicContact CG2-CD1 4.08Å; I163-L227 HydrophobicContact CG2-CD2 3.93Å; I163-L227 HydrophobicContact CG2-CG 4.42Å; S223-L227 WeakPolarHBondContact O-CD1 3.47Å; S223-L227 VanDerWaalsContact O-CG 3.3Å; S223-L227 WeakPolarHBondContact O-CG 3.15Å; S223-L227 PolarHBondContact O-N 2.83Å; I224-L227 PolarHBondContact O-N 2.91Å; V225-L227 VanDerWaalsContact C-N 3.35Å; V225-L227 PolarHBondContact O-N 2.83Å
228	F	98.2	Very high	96.7	Very high	2 Å²	2	37.8 Å²	37.8	1%	0.009	20%	0.198	C	C	.	.	T	Hydrogen-bonded Turn	trans	-99.8	11.4	-179.8	-73.5	-91.1	0	0	0	113.6	L140 I144 V167 M179 L183 I224 V225 P226 Y230 M231 N232 L244	L140-F228 HydrophobicContact CB-CZ 4.46Å; L140-F228 HydrophobicContact CD1-CE1 4.35Å; L140-F228 HydrophobicContact CD1-CZ 4.48Å; L140-F228 HydrophobicContact CD2-CZ 4.5Å; I144-F228 HydrophobicContact CD1-CE2 4.21Å; I144-F228 HydrophobicContact CD1-CZ 3.89Å; I144-F228 HydrophobicContact CG1-CE2 4.13Å; I144-F228 HydrophobicContact CG1-CZ 4.28Å; V167-F228 HydrophobicContact CG1-CD1 4.17Å; V167-F228 HydrophobicContact CG2-CD1 3.85Å; V167-F228 HydrophobicContact CG2-CE1 3.7Å; V167-F228 HydrophobicContact CG2-CG 4.38Å; V167-F228 HydrophobicContact CG2-CZ 4.08Å; M179-F228 HydrophobicContact CG-CE1 4.05Å; M179-F228 HydrophobicContact SD-CD1 3.84Å; M179-F228 HydrophobicContact SD-CE1 3.62Å; L183-F228 HydrophobicContact CD1-CE2 4.27Å; L183-F228 HydrophobicContact CD1-CZ 4.24Å; L183-F228 HydrophobicContact CD2-CD1 4.1Å; L183-F228 HydrophobicContact CD2-CD2 4.41Å; L183-F228 HydrophobicContact CD2-CE1 4.32Å; L183-F228 HydrophobicContact CD2-CG 4.14Å; I224-F228 HydrophobicContact CG2-CD2 4Å; I224-F228 HydrophobicContact CG2-CE2 4.36Å; I224-F228 WeakPolarHBondContact O-CD2 3.28Å; I224-F228 PolarHBondContact O-N 3.31Å; I224-F228 VanDerWaalsContact O-N 3.13Å; V225-F228 CarbonylContact O-C 3.58Å; V225-F228 PolarHBondContact O-N 3.32Å; P226-F228 PolarHBondContact O-N 2.96Å; F228-Y230 PolarHBondContact O-N 3.25Å; F228-Y230 VanDerWaalsContact O-N 3.12Å; F228-M231 HydrophobicContact CB-CE 4.22Å; F228-M231 HydrophobicContact CD1-CE 3.65Å; F228-M231 HydrophobicContact CD1-SD 4.29Å; F228-M231 HydrophobicContact CE1-CE 4.47Å; F228-M231 HydrophobicContact CG-CE 4.27Å; F228-M231 WeakPolarHBondContact O-CA 3.41Å; F228-M231 WeakPolarHBondContact O-CB 3.23Å; F228-M231 PolarHBondContact O-N 3.35Å; F228-N232 PolarHBondContact O-N 3.45Å; F228-L244 HydrophobicContact CB-CD2 3.58Å
229	I	97.7	Very high	96.7	Very high	59 Å²	59	43.5 Å²	43.5	30%	0.303	22%	0.222	S	C	.	.	H	α-helix	trans	-57.4	-34.9	-174.2	-167.8	61.2	0	0	0	112.8	Y164 V225 P226 N232 K233	Y164-I229 HydrophobicContact CE2-CG2 3.8Å; V225-I229 PolarHBondContact O-N 3.23Å; P226-I229 WeakPolarHBondContact O-CB 3.37Å; P226-I229 WeakPolarHBondContact O-CG2 3.45Å; P226-I229 PolarHBondContact O-N 3.32Å; I229-N232 HydrophobicContact CD1-CB 4.45Å; I229-N232 WeakPolarHBondContact O-CB 3.42Å; I229-N232 PolarHBondContact O-N 3.07Å; I229-K233 HydrophobicContact CG1-CG 4.4Å; I229-K233 WeakPolarHBondContact O-CG 3.47Å; I229-K233 PolarHBondContact O-N 3.28Å
230	Y	97.7	Very high	96.9	Very high	41 Å²	41	45 Å²	45	16%	0.161	22%	0.224	C	C	.	.	H	α-helix	trans	-66.7	-41.1	177.5	-163.7	-98.6	0	0	0	111.6	Y168 V171 F228 N232 F234	Y168-Y230 AromaticContact CD2-CD1 3.84Å; Y168-Y230 HydrophobicContact CD2-CD1 3.84Å; Y168-Y230 AromaticContact CD2-CD2 3.83Å; Y168-Y230 HydrophobicContact CD2-CD2 3.83Å; Y168-Y230 AromaticContact CD2-CE1 3.65Å; Y168-Y230 HydrophobicContact CD2-CE1 3.65Å; Y168-Y230 AromaticContact CD2-CE2 3.62Å; Y168-Y230 HydrophobicContact CD2-CE2 3.62Å; Y168-Y230 AromaticContact CD2-CG 3.93Å; Y168-Y230 HydrophobicContact CD2-CG 3.93Å; Y168-Y230 AromaticContact CD2-CZ 3.55Å; Y168-Y230 HydrophobicContact CE2-CD1 4.49Å; Y168-Y230 HydrophobicContact CE2-CD2 4.21Å; Y168-Y230 AromaticContact CE2-CE1 3.88Å; Y168-Y230 HydrophobicContact CE2-CE1 3.88Å; Y168-Y230 AromaticContact CE2-CE2 3.53Å; Y168-Y230 HydrophobicContact CE2-CE2 3.53Å; Y168-Y230 AromaticContact CE2-CZ 3.36Å; Y168-Y230 WeakPolarHBondContact CE2-OH 3.36Å; V171-Y230 HydrophobicContact CB-CD1 3.7Å; V171-Y230 HydrophobicContact CB-CE1 3.9Å; V171-Y230 HydrophobicContact CG1-CD1 3.58Å; V171-Y230 HydrophobicContact CG1-CE1 3.56Å; V171-Y230 HydrophobicContact CG2-CD1 4.15Å; F228-Y230 PolarHBondContact O-N 3.25Å; F228-Y230 VanDerWaalsContact O-N 3.12Å; Y230-N232 VanDerWaalsContact C-N 3.34Å; Y230-F234 AromaticContact CD1-CD2 3.92Å; Y230-F234 HydrophobicContact CD1-CD2 3.92Å; Y230-F234 HydrophobicContact CD1-CE2 4.38Å; Y230-F234 AromaticContact CD2-CD2 3.72Å; Y230-F234 HydrophobicContact CD2-CD2 3.72Å; Y230-F234 AromaticContact CD2-CE2 3.48Å; Y230-F234 HydrophobicContact CD2-CE2 3.48Å; Y230-F234 VanDerWaalsContact CD2-CE2 3.48Å; Y230-F234 AromaticContact CE1-CD2 3.74Å; Y230-F234 HydrophobicContact CE1-CD2 3.74Å; Y230-F234 AromaticContact CE1-CE2 3.98Å; Y230-F234 HydrophobicContact CE1-CE2 3.98Å; Y230-F234 HydrophobicContact CE1-CG 4.15Å; Y230-F234 AromaticContact CE2-CD2 3.54Å; Y230-F234 HydrophobicContact CE2-CD2 3.54Å; Y230-F234 AromaticContact CE2-CE2 2.99Å; Y230-F234 HydrophobicContact CE2-CE2 2.99Å; Y230-F234 AromaticContact CE2-CZ 3.63Å; Y230-F234 HydrophobicContact CE2-CZ 3.63Å; Y230-F234 AromaticContact CG-CD2 3.91Å; Y230-F234 HydrophobicContact CG-CD2 3.91Å; Y230-F234 HydrophobicContact CG-CE2 4.16Å; Y230-F234 AromaticContact CZ-CD2 3.53Å; Y230-F234 AromaticContact CZ-CE2 3.26Å; Y230-F234 AromaticContact CZ-CZ 3.62Å; Y230-F234 WeakPolarHBondContact O-CB 3.37Å; Y230-F234 VanDerWaalsContact O-CD2 3.27Å; Y230-F234 WeakPolarHBondContact O-CD2 3.41Å; Y230-F234 PolarHBondContact O-N 3.06Å; Y230-F234 WeakPolarHBondContact OH-CZ 3.25Å
231	M	97.8	Very high	97	Very high	0 Å²	0	51.9 Å²	51.9	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-64.7	-40	172.4	-178.1	179.7	73.1	0	0	111.3	V167 V171 M179 Y180 L183 F228 Y235 I236	V167-M231 HydrophobicContact CG1-CB 4.37Å; V171-M231 HydrophobicContact CG2-CB 3.89Å; V171-M231 HydrophobicContact CG2-CG 4.4Å; M179-M231 HydrophobicContact CB-SD 3.9Å; M179-M231 HydrophobicContact CG-SD 3.75Å; M179-M231 HydrophobicContact SD-CB 4.5Å; M179-M231 HydrophobicContact SD-SD 3.57Å; Y180-M231 HydrophobicContact CD2-CE 4.37Å; L183-M231 HydrophobicContact CD2-CE 3.69Å; F228-M231 HydrophobicContact CB-CE 4.22Å; F228-M231 HydrophobicContact CD1-CE 3.65Å; F228-M231 HydrophobicContact CD1-SD 4.29Å; F228-M231 HydrophobicContact CE1-CE 4.47Å; F228-M231 HydrophobicContact CG-CE 4.27Å; F228-M231 WeakPolarHBondContact O-CA 3.41Å; F228-M231 WeakPolarHBondContact O-CB 3.23Å; F228-M231 PolarHBondContact O-N 3.35Å; M231-Y235 WeakPolarHBondContact O-CB 3.46Å; M231-Y235 PolarHBondContact O-N 3.41Å; M231-I236 HydrophobicContact CE-CD1 4.18Å; M231-I236 PolarHBondContact O-N 3.19Å
232	N	97.9	Very high	97.1	Very high	2 Å²	2	56.3 Å²	56.3	1%	0.011	28%	0.277	C	S	.	.	I	π-helix	trans	-57.1	-54.4	176.2	-166.6	39.9	0	0	0	111	F228 I229 Y230 F234 I236 E237 D243 L244	F228-N232 PolarHBondContact O-N 3.45Å; I229-N232 HydrophobicContact CD1-CB 4.45Å; I229-N232 WeakPolarHBondContact O-CB 3.42Å; I229-N232 PolarHBondContact O-N 3.07Å; Y230-N232 VanDerWaalsContact C-N 3.34Å; N232-F234 PolarHBondContact O-N 3.36Å; N232-I236 PolarHBondContact O-N 3.35Å; N232-I236 VanDerWaalsContact O-N 3.16Å; N232-E237 PolarHBondContact ND2-OE1 3.49Å; N232-E237 PolarHBondContact O-N 3.08Å; N232-D243 PolarHBondContact ND2-OD2 3.34Å; N232-L244 HydrophobicContact CB-CB 4.07Å; N232-L244 HydrophobicContact CB-CD2 4.49Å; N232-L244 VanDerWaalsContact OD1-CB 3.27Å; N232-L244 WeakPolarHBondContact OD1-CB 3.3Å; N232-L244 PolarHBondContact OD1-N 3.37Å
233	K	97.1	Very high	97.3	Very high	97 Å²	97	52.8 Å²	52.8	42%	0.422	26%	0.261	S	S	.	.	I	π-helix	trans	-63.5	-41.3	-178.9	-68	-48.3	-169.7	-171.8	0	113.8	I229 E237 T238	I229-K233 HydrophobicContact CG1-CG 4.4Å; I229-K233 WeakPolarHBondContact O-CG 3.47Å; I229-K233 PolarHBondContact O-N 3.28Å; K233-E237 WeakPolarHBondContact CD-OE1 3.15Å; K233-E237 WeakPolarHBondContact CD-OE2 3.33Å; K233-E237 IonicContact NZ-OE1 3.96Å; K233-E237 PolarHBondContact NZ-OE1 3.24Å; K233-E237 IonicContact NZ-OE2 3.98Å; K233-E237 PolarHBondContact NZ-OE2 3.29Å; K233-T238 WeakPolarHBondContact O-CG2 3.4Å
234	F	96.4	Very high	97.5	Very high	110 Å²	110	51.5 Å²	51.5	48%	0.482	25%	0.253	S	S	.	.	I	π-helix	trans	-91.8	-19.5	-171	-80	-91.8	0	0	0	115	V171 Y230 N232 T238	V171-F234 HydrophobicContact CG1-CB 4.06Å; Y230-F234 AromaticContact CD1-CD2 3.92Å; Y230-F234 HydrophobicContact CD1-CD2 3.92Å; Y230-F234 HydrophobicContact CD1-CE2 4.38Å; Y230-F234 AromaticContact CD2-CD2 3.72Å; Y230-F234 HydrophobicContact CD2-CD2 3.72Å; Y230-F234 AromaticContact CD2-CE2 3.48Å; Y230-F234 HydrophobicContact CD2-CE2 3.48Å; Y230-F234 VanDerWaalsContact CD2-CE2 3.48Å; Y230-F234 AromaticContact CE1-CD2 3.74Å; Y230-F234 HydrophobicContact CE1-CD2 3.74Å; Y230-F234 AromaticContact CE1-CE2 3.98Å; Y230-F234 HydrophobicContact CE1-CE2 3.98Å; Y230-F234 HydrophobicContact CE1-CG 4.15Å; Y230-F234 AromaticContact CE2-CD2 3.54Å; Y230-F234 HydrophobicContact CE2-CD2 3.54Å; Y230-F234 AromaticContact CE2-CE2 2.99Å; Y230-F234 HydrophobicContact CE2-CE2 2.99Å; Y230-F234 AromaticContact CE2-CZ 3.63Å; Y230-F234 HydrophobicContact CE2-CZ 3.63Å; Y230-F234 AromaticContact CG-CD2 3.91Å; Y230-F234 HydrophobicContact CG-CD2 3.91Å; Y230-F234 HydrophobicContact CG-CE2 4.16Å; Y230-F234 AromaticContact CZ-CD2 3.53Å; Y230-F234 AromaticContact CZ-CE2 3.26Å; Y230-F234 AromaticContact CZ-CZ 3.62Å; Y230-F234 WeakPolarHBondContact O-CB 3.37Å; Y230-F234 VanDerWaalsContact O-CD2 3.27Å; Y230-F234 WeakPolarHBondContact O-CD2 3.41Å; Y230-F234 PolarHBondContact O-N 3.06Å; Y230-F234 WeakPolarHBondContact OH-CZ 3.25Å; N232-F234 PolarHBondContact O-N 3.36Å; F234-T238 PolarHBondContact O-OG1 3.02Å
235	Y	97.5	Very high	97.5	Very high	16 Å²	16	55.8 Å²	55.8	6%	0.063	27%	0.271	C	S	.	.	I	π-helix	trans	-125	-53.6	-176.6	177.1	-114.7	0	0	0	112.7	S176 E177 Y180 M231 K239 L240	S176-Y235 WeakPolarHBondContact OG-CD2 3.34Å; E177-Y235 HydrophobicContact CB-CE1 4.27Å; E177-Y235 HydrophobicContact CB-CE2 3.93Å; E177-Y235 WeakPolarHBondContact CG-OH 3.2Å; Y180-Y235 HydrophobicContact CD1-CE1 4.03Å; Y180-Y235 HydrophobicContact CG-CD1 4.41Å; Y180-Y235 AromaticContact CG-CE1 3.97Å; Y180-Y235 HydrophobicContact CG-CE1 3.97Å; M231-Y235 WeakPolarHBondContact O-CB 3.46Å; M231-Y235 PolarHBondContact O-N 3.41Å; Y235-K239 HydrophobicContact CD2-CB 4.2Å; Y235-K239 HydrophobicContact CD2-CD 3.77Å; Y235-K239 HydrophobicContact CD2-CG 4.16Å; Y235-K239 HydrophobicContact CE2-CB 4.32Å; Y235-K239 HydrophobicContact CE2-CD 4Å; Y235-K239 WeakPolarHBondContact O-CA 3.46Å; Y235-K239 VanDerWaalsContact O-CB 3.23Å; Y235-K239 WeakPolarHBondContact O-CB 3.3Å; Y235-K239 PolarHBondContact O-N 3.13Å; Y235-L240 HydrophobicContact CD1-CD1 4.29Å; Y235-L240 HydrophobicContact CE1-CD1 3.64Å; Y235-L240 HydrophobicContact CE1-CG 4.32Å; Y235-L240 PolarHBondContact O-N 3.36Å
236	I	97.8	Very high	97.5	Very high	0 Å²	0	59.6 Å²	59.6	0%	0	29%	0.291	C	S	.	.	I	π-helix	trans	-72.4	-52	-170.9	-53.7	175	0	0	0	110.4	Y180 M231 N232 L240 N241 R242 L244	Y180-I236 HydrophobicContact CD2-CD1 3.54Å; Y180-I236 HydrophobicContact CD2-CG1 3.93Å; Y180-I236 HydrophobicContact CE2-CD1 3.85Å; Y180-I236 HydrophobicContact CE2-CG1 4.27Å; M231-I236 HydrophobicContact CE-CD1 4.18Å; M231-I236 PolarHBondContact O-N 3.19Å; N232-I236 PolarHBondContact O-N 3.35Å; N232-I236 VanDerWaalsContact O-N 3.16Å; I236-L240 CarbonylContact O-C 3.36Å; I236-L240 WeakPolarHBondContact O-CA 3.33Å; I236-L240 VanDerWaalsContact O-CB 3.3Å; I236-L240 WeakPolarHBondContact O-CB 3.29Å; I236-L240 PolarHBondContact O-N 3.22Å; I236-N241 PolarHBondContact O-N 2.8Å; I236-R242 CarbonylContact C-O 3.58Å; I236-R242 HydrophobicContact CG2-CB 3.98Å; I236-R242 WeakPolarHBondContact CG2-O 3.33Å; I236-R242 PolarHBondContact O-N 3.21Å; I236-L244 HydrophobicContact CD1-CB 3.81Å; I236-L244 HydrophobicContact CD1-CD1 3.74Å; I236-L244 HydrophobicContact CD1-CD2 4.49Å; I236-L244 HydrophobicContact CD1-CG 4.21Å
237	E	97.8	Very high	97.6	Very high	62 Å²	62	56.9 Å²	56.9	29%	0.29	27%	0.272	S	S	.	.	I	π-helix	trans	-66	-46.8	178.4	-71.5	-179.2	-166.4	0	0	111.3	N232 K233 N241 R242	N232-E237 PolarHBondContact ND2-OE1 3.49Å; N232-E237 PolarHBondContact O-N 3.08Å; K233-E237 WeakPolarHBondContact CD-OE1 3.15Å; K233-E237 WeakPolarHBondContact CD-OE2 3.33Å; K233-E237 IonicContact NZ-OE1 3.96Å; K233-E237 PolarHBondContact NZ-OE1 3.24Å; K233-E237 IonicContact NZ-OE2 3.98Å; K233-E237 PolarHBondContact NZ-OE2 3.29Å; E237-N241 WeakPolarHBondContact O-CA 3.45Å; E237-N241 PolarHBondContact O-N 3.13Å; E237-R242 WeakPolarHBondContact CA-O 3.44Å; E237-R242 PolarHBondContact N-O 3.41Å
238	T	96.5	Very high	97.6	Very high	96 Å²	96	56.6 Å²	56.6	59%	0.589	27%	0.271	S	S	*	.	I	π-helix	trans	-79.5	-36.9	-171.7	54.2	0	0	0	0	114.4	K233 F234	K233-T238 WeakPolarHBondContact O-CG2 3.4Å; F234-T238 PolarHBondContact O-OG1 3.02Å
239	K	96.8	Very high	97.6	Very high	148 Å²	148	57.5 Å²	57.5	64%	0.643	28%	0.276	S	S	*	.	I	π-helix	trans	-103.1	-33.9	-176.7	-55.9	-160.6	-172.4	175.8	0	113.3	Y235	Y235-K239 HydrophobicContact CD2-CB 4.2Å; Y235-K239 HydrophobicContact CD2-CD 3.77Å; Y235-K239 HydrophobicContact CD2-CG 4.16Å; Y235-K239 HydrophobicContact CE2-CB 4.32Å; Y235-K239 HydrophobicContact CE2-CD 4Å; Y235-K239 WeakPolarHBondContact O-CA 3.46Å; Y235-K239 VanDerWaalsContact O-CB 3.23Å; Y235-K239 WeakPolarHBondContact O-CB 3.3Å; Y235-K239 PolarHBondContact O-N 3.13Å
240	L	97.1	Very high	97.7	Very high	54 Å²	54	59.9 Å²	59.9	28%	0.283	28%	0.284	S	S	.	.	I	π-helix	trans	-101.8	-12	-176.9	-49.3	179.4	0	0	0	112.7	Y180 Y235 I236 R242	Y180-L240 HydrophobicContact CD1-CD1 4.44Å; Y180-L240 HydrophobicContact CE1-CD1 4.23Å; Y235-L240 HydrophobicContact CD1-CD1 4.29Å; Y235-L240 HydrophobicContact CE1-CD1 3.64Å; Y235-L240 HydrophobicContact CE1-CG 4.32Å; Y235-L240 PolarHBondContact O-N 3.36Å; I236-L240 CarbonylContact O-C 3.36Å; I236-L240 WeakPolarHBondContact O-CA 3.33Å; I236-L240 VanDerWaalsContact O-CB 3.3Å; I236-L240 WeakPolarHBondContact O-CB 3.29Å; I236-L240 PolarHBondContact O-N 3.22Å; L240-R242 VanDerWaalsContact C-N 3.28Å; L240-R242 PolarHBondContact O-N 2.87Å
241	N	97.7	Very high	97.7	Very high	148 Å²	148	58.6 Å²	58.6	79%	0.791	28%	0.279	S	S	*	.			trans	52	46.4	-176.7	-166.2	58.2	0	0	0	112.5	I236 E237	I236-N241 PolarHBondContact O-N 2.8Å; E237-N241 WeakPolarHBondContact O-CA 3.45Å; E237-N241 PolarHBondContact O-N 3.13Å
242	R	97.8	Very high	97.7	Very high	100 Å²	100	58.6 Å²	58.6	38%	0.377	28%	0.28	S	S	.	.			trans	-135.5	172.9	179.7	-70.9	-174.9	-67.7	139	5.4	110.1	Y180 I236 E237 L240 D247	Y180-R242 PolarHBondContact OH-NH1 3.48Å; Y180-R242 PolarHBondContact OH-NH2 2.93Å; Y180-R242 VanDerWaalsContact OH-NH2 3.14Å; I236-R242 CarbonylContact C-O 3.58Å; I236-R242 HydrophobicContact CG2-CB 3.98Å; I236-R242 WeakPolarHBondContact CG2-O 3.33Å; I236-R242 PolarHBondContact O-N 3.21Å; E237-R242 WeakPolarHBondContact CA-O 3.44Å; E237-R242 PolarHBondContact N-O 3.41Å; L240-R242 VanDerWaalsContact C-N 3.28Å; L240-R242 PolarHBondContact O-N 2.87Å; R242-D247 IonicContact CZ-OD1 3.72Å; R242-D247 IonicContact CZ-OD2 2.65Å; R242-D247 IonicContact NE-OD2 3.8Å; R242-D247 IonicContact NH1-OD1 3.38Å; R242-D247 PolarHBondContact NH1-OD1 2.74Å; R242-D247 IonicContact NH1-OD2 2.93Å; R242-D247 PolarHBondContact NH1-OD2 3.46Å; R242-D247 IonicContact NH2-OD2 3.69Å
243	D	97.7	Very high	97.8	Very high	46 Å²	46	58.8 Å²	58.8	25%	0.246	28%	0.281	C	S	.	.			trans	-116.3	138.7	172.2	-179.5	-98.9	0	0	0	111.3	N232 K245 D246 D247	N232-D243 PolarHBondContact ND2-OD2 3.34Å; D243-K245 PolarHBondContact O-N 2.91Å; D243-K245 WeakPolarHBondContact OD1-CA 3.44Å; D243-K245 WeakPolarHBondContact OD1-CB 3.27Å; D243-K245 PolarHBondContact OD1-N 3Å; D243-D246 HydrophobicContact CB-CB 4.34Å; D243-D246 PolarHBondContact O-N 3.12Å; D243-D246 PolarHBondContact OD1-N 3.27Å; D243-D247 PolarHBondContact O-N 3.03Å
244	L	98.3	Very high	97.8	Very high	0 Å²	0	57.6 Å²	57.6	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-61.5	-41.7	-179.7	-179.9	59.6	0	0	0	112.3	L183 F228 N232 I236 D246 D247 L248	L183-L244 HydrophobicContact CD2-CD1 3.99Å; F228-L244 HydrophobicContact CB-CD2 3.58Å; N232-L244 HydrophobicContact CB-CB 4.07Å; N232-L244 HydrophobicContact CB-CD2 4.49Å; N232-L244 VanDerWaalsContact OD1-CB 3.27Å; N232-L244 WeakPolarHBondContact OD1-CB 3.3Å; N232-L244 PolarHBondContact OD1-N 3.37Å; I236-L244 HydrophobicContact CD1-CB 3.81Å; I236-L244 HydrophobicContact CD1-CD1 3.74Å; I236-L244 HydrophobicContact CD1-CD2 4.49Å; I236-L244 HydrophobicContact CD1-CG 4.21Å; L244-D246 VanDerWaalsContact C-N 3.29Å; L244-D246 PolarHBondContact O-N 3.46Å; L244-D247 PolarHBondContact O-N 3.37Å; L244-L248 HydrophobicContact CD1-CD1 4.07Å; L244-L248 HydrophobicContact CD1-CD2 4.3Å; L244-L248 HydrophobicContact CD1-CG 3.96Å; L244-L248 HydrophobicContact CG-CD1 4.08Å; L244-L248 HydrophobicContact CG-CG 4.3Å; L244-L248 VanDerWaalsContact O-CG 3.24Å; L244-L248 WeakPolarHBondContact O-CG 3.46Å; L244-L248 PolarHBondContact O-N 3.4Å
245	K	97.9	Very high	97.9	Very high	89 Å²	89	54.2 Å²	54.2	39%	0.387	26%	0.262	S	S	.	.	H	α-helix	trans	-62.3	-43.8	-178.8	-175.6	-173.6	170.7	-173.7	0	109.7	V225 D243 L248 I249	V225-K245 HydrophobicContact CG1-CB 4.36Å; V225-K245 HydrophobicContact CG2-CB 4.01Å; V225-K245 HydrophobicContact CG2-CG 4.32Å; D243-K245 PolarHBondContact O-N 2.91Å; D243-K245 WeakPolarHBondContact OD1-CA 3.44Å; D243-K245 WeakPolarHBondContact OD1-CB 3.27Å; D243-K245 PolarHBondContact OD1-N 3Å; K245-L248 PolarHBondContact O-N 3.47Å; K245-I249 HydrophobicContact CD-CD1 4.49Å; K245-I249 HydrophobicContact CG-CD1 3.91Å; K245-I249 HydrophobicContact CG-CG1 4.49Å; K245-I249 WeakPolarHBondContact O-CB 3.39Å; K245-I249 VanDerWaalsContact O-CG1 3.28Å; K245-I249 WeakPolarHBondContact O-CG1 3.27Å; K245-I249 PolarHBondContact O-N 3.35Å
246	D	98.1	Very high	97.9	Very high	102 Å²	102	53.4 Å²	53.4	55%	0.545	26%	0.259	S	S	.	.	H	α-helix	trans	-64.3	-44	178.1	-66.7	-16.8	0	0	0	111.8	D243 L244 L248 I249 K250	D243-D246 HydrophobicContact CB-CB 4.34Å; D243-D246 PolarHBondContact O-N 3.12Å; D243-D246 PolarHBondContact OD1-N 3.27Å; L244-D246 VanDerWaalsContact C-N 3.29Å; L244-D246 PolarHBondContact O-N 3.46Å; D246-L248 VanDerWaalsContact C-N 3.29Å; D246-L248 PolarHBondContact O-N 2.77Å; D246-I249 PolarHBondContact O-N 2.89Å; D246-K250 VanDerWaalsContact O-CB 3.28Å; D246-K250 WeakPolarHBondContact O-CB 2.74Å; D246-K250 PolarHBondContact O-N 3.16Å
247	D	98.3	Very high	97.9	Very high	16 Å²	16	53.4 Å²	53.4	9%	0.086	26%	0.259	C	S	.	.	H	α-helix	trans	-58.2	-41.6	174.8	-81.4	-19.5	0	0	0	111.4	Y180 R242 D243 L244 K250 L251	Y180-D247 PolarHBondContact OH-OD2 3.33Å; R242-D247 IonicContact CZ-OD1 3.72Å; R242-D247 IonicContact CZ-OD2 2.65Å; R242-D247 IonicContact NE-OD2 3.8Å; R242-D247 IonicContact NH1-OD1 3.38Å; R242-D247 PolarHBondContact NH1-OD1 2.74Å; R242-D247 IonicContact NH1-OD2 2.93Å; R242-D247 PolarHBondContact NH1-OD2 3.46Å; R242-D247 IonicContact NH2-OD2 3.69Å; D243-D247 PolarHBondContact O-N 3.03Å; L244-D247 PolarHBondContact O-N 3.37Å; D247-K250 WeakPolarHBondContact O-CB 3.46Å; D247-K250 PolarHBondContact O-N 3.35Å; D247-L251 WeakPolarHBondContact O-CG 3.44Å; D247-L251 PolarHBondContact O-N 3Å; D247-L251 VanDerWaalsContact O-N 3.15Å
248	L	98.5	Very high	97.9	Very high	0 Å²	0	53.9 Å²	53.9	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-73.1	-40.6	179	-63.9	-176.1	0	0	0	112.9	I184 I187 Y217 L221 I224 V225 L244 K245 D246 K250 L251 F252	I184-L248 HydrophobicContact CD1-CD2 3.99Å; I187-L248 HydrophobicContact CD1-CD1 4.18Å; I187-L248 HydrophobicContact CD1-CD2 3.49Å; I187-L248 VanDerWaalsContact CD1-CD2 3.49Å; I187-L248 HydrophobicContact CD1-CG 4.45Å; Y217-L248 PolarHBondContact OH-O 3.33Å; L221-L248 HydrophobicContact CD1-CB 4.2Å; L221-L248 HydrophobicContact CD2-CB 3.73Å; L221-L248 HydrophobicContact CD2-CD1 3.69Å; L221-L248 HydrophobicContact CD2-CG 4.32Å; I224-L248 HydrophobicContact CG2-CD1 3.99Å; V225-L248 HydrophobicContact CG2-CD1 4.24Å; L244-L248 HydrophobicContact CD1-CD1 4.07Å; L244-L248 HydrophobicContact CD1-CD2 4.3Å; L244-L248 HydrophobicContact CD1-CG 3.96Å; L244-L248 HydrophobicContact CG-CD1 4.08Å; L244-L248 HydrophobicContact CG-CG 4.3Å; L244-L248 VanDerWaalsContact O-CG 3.24Å; L244-L248 WeakPolarHBondContact O-CG 3.46Å; L244-L248 PolarHBondContact O-N 3.4Å; K245-L248 PolarHBondContact O-N 3.47Å; D246-L248 VanDerWaalsContact C-N 3.29Å; D246-L248 PolarHBondContact O-N 2.77Å; L248-K250 PolarHBondContact O-N 3.47Å; L248-L251 HydrophobicContact CD2-CD1 3.95Å; L248-L251 WeakPolarHBondContact O-CB 3.45Å; L248-L251 PolarHBondContact O-N 2.9Å; L248-L251 VanDerWaalsContact O-N 3.14Å; L248-F252 PolarHBondContact O-N 2.96Å
249	I	98.2	Very high	97.9	Very high	21 Å²	21	54.4 Å²	54.4	11%	0.108	26%	0.256	C	S	.	.	H	α-helix	trans	-58.7	-41.3	172.6	-71.8	171.5	0	0	0	110.2	L221 K245 D246 L251 F252 T253 L293	L221-I249 HydrophobicContact CD1-CG1 3.88Å; K245-I249 HydrophobicContact CD-CD1 4.49Å; K245-I249 HydrophobicContact CG-CD1 3.91Å; K245-I249 HydrophobicContact CG-CG1 4.49Å; K245-I249 WeakPolarHBondContact O-CB 3.39Å; K245-I249 VanDerWaalsContact O-CG1 3.28Å; K245-I249 WeakPolarHBondContact O-CG1 3.27Å; K245-I249 PolarHBondContact O-N 3.35Å; D246-I249 PolarHBondContact O-N 2.89Å; I249-L251 VanDerWaalsContact C-N 3.33Å; I249-L251 PolarHBondContact O-N 3.05Å; I249-F252 PolarHBondContact O-N 2.88Å; I249-T253 PolarHBondContact O-N 3.35Å; I249-T253 PolarHBondContact O-OG1 3.12Å; I249-L293 HydrophobicContact CG2-CD2 4.06Å
250	K	98.2	Very high	97.9	Very high	110 Å²	110	47.7 Å²	47.7	48%	0.478	23%	0.226	S	C	.	.	H	α-helix	trans	-60.7	-40	176.2	-176.9	176.1	174.9	178.8	0	112.1	D246 D247 L248 F252 T253 E254	D246-K250 VanDerWaalsContact O-CB 3.28Å; D246-K250 WeakPolarHBondContact O-CB 2.74Å; D246-K250 PolarHBondContact O-N 3.16Å; D247-K250 WeakPolarHBondContact O-CB 3.46Å; D247-K250 PolarHBondContact O-N 3.35Å; L248-K250 PolarHBondContact O-N 3.47Å; K250-F252 PolarHBondContact O-N 3.02Å; K250-T253 WeakPolarHBondContact O-CB 3.46Å; K250-T253 PolarHBondContact O-N 2.96Å; K250-T253 VanDerWaalsContact O-N 3.14Å; K250-E254 WeakPolarHBondContact CE-OE1 3.36Å; K250-E254 HydrophobicContact CG-CG 4.26Å; K250-E254 IonicContact NZ-OE1 3.1Å; K250-E254 WeakPolarHBondContact O-CG 3.37Å; K250-E254 PolarHBondContact O-N 2.96Å
251	L	98.6	Very high	97.9	Very high	13 Å²	13	45.2 Å²	45.2	7%	0.068	21%	0.214	C	C	.	.	H	α-helix	trans	-59.1	-45	176.4	-68	-179.1	0	0	0	112.7	I184 I187 L191 D247 L248 I249 T253 H255	I184-L251 HydrophobicContact CD1-CD1 3.92Å; I184-L251 HydrophobicContact CG2-CD1 4.16Å; I184-L251 HydrophobicContact CG2-CD2 4.17Å; I187-L251 HydrophobicContact CB-CD1 4.07Å; I187-L251 HydrophobicContact CG2-CD1 3.7Å; L191-L251 HydrophobicContact CD1-CB 3.67Å; D247-L251 WeakPolarHBondContact O-CG 3.44Å; D247-L251 PolarHBondContact O-N 3Å; D247-L251 VanDerWaalsContact O-N 3.15Å; L248-L251 HydrophobicContact CD2-CD1 3.95Å; L248-L251 WeakPolarHBondContact O-CB 3.45Å; L248-L251 PolarHBondContact O-N 2.9Å; L248-L251 VanDerWaalsContact O-N 3.14Å; I249-L251 VanDerWaalsContact C-N 3.33Å; I249-L251 PolarHBondContact O-N 3.05Å; L251-T253 VanDerWaalsContact C-N 3.3Å; L251-T253 PolarHBondContact O-N 2.96Å; L251-H255 WeakPolarHBondContact O-CB 3.46Å; L251-H255 PolarHBondContact O-CD2 2.85Å; L251-H255 PolarHBondContact O-N 3.14Å
252	F	98.6	Very high	97.7	Very high	1 Å²	1	46.7 Å²	46.7	0%	0.004	21%	0.209	C	C	.	.	H	α-helix	trans	-64.9	-39.2	176.3	-170.3	-81.1	0	0	0	111.5	L191 F210 L214 Y217 L248 I249 K250 V256 A257 L293	L191-F252 HydrophobicContact CD1-CB 4.43Å; L191-F252 HydrophobicContact CD2-CB 4.49Å; L191-F252 HydrophobicContact CD2-CD2 3.57Å; L191-F252 HydrophobicContact CD2-CE2 4.24Å; L191-F252 HydrophobicContact CD2-CG 4.42Å; F210-F252 HydrophobicContact CZ-CE1 4.45Å; L214-F252 HydrophobicContact CB-CZ 4.1Å; L214-F252 HydrophobicContact CD1-CD1 4.3Å; L214-F252 HydrophobicContact CD1-CE1 3.7Å; L214-F252 HydrophobicContact CD1-CZ 3.98Å; Y217-F252 HydrophobicContact CD1-CB 3.64Å; Y217-F252 AromaticContact CD1-CD2 3.35Å; Y217-F252 HydrophobicContact CD1-CD2 3.35Å; Y217-F252 HydrophobicContact CD1-CE2 4.26Å; Y217-F252 AromaticContact CD1-CG 3.74Å; Y217-F252 HydrophobicContact CD1-CG 3.74Å; Y217-F252 HydrophobicContact CD2-CD2 4.24Å; Y217-F252 HydrophobicContact CE1-CB 3.44Å; Y217-F252 VanDerWaalsContact CE1-CB 3.44Å; Y217-F252 AromaticContact CE1-CD2 4Å; Y217-F252 HydrophobicContact CE1-CD2 4Å; Y217-F252 HydrophobicContact CE1-CG 4.1Å; Y217-F252 AromaticContact CG-CD2 3.48Å; Y217-F252 HydrophobicContact CG-CD2 3.48Å; Y217-F252 VanDerWaalsContact CG-CD2 3.48Å; Y217-F252 HydrophobicContact CG-CE2 4.1Å; Y217-F252 HydrophobicContact CG-CG 4.33Å; L248-F252 PolarHBondContact O-N 2.96Å; I249-F252 PolarHBondContact O-N 2.88Å; K250-F252 PolarHBondContact O-N 3.02Å; F252-V256 HydrophobicContact CD1-CB 4.27Å; F252-V256 HydrophobicContact CD2-CB 4.38Å; F252-V256 HydrophobicContact CD2-CG2 4.23Å; F252-V256 HydrophobicContact CE1-CB 4.13Å; F252-V256 HydrophobicContact CE1-CG1 4.1Å; F252-V256 HydrophobicContact CE2-CB 4.25Å; F252-V256 HydrophobicContact CE2-CG1 4.2Å; F252-V256 HydrophobicContact CE2-CG2 4.26Å; F252-V256 HydrophobicContact CG-CB 4.39Å; F252-V256 HydrophobicContact CZ-CB 4.12Å; F252-V256 HydrophobicContact CZ-CG1 3.81Å; F252-V256 WeakPolarHBondContact O-CA 3.5Å; F252-V256 WeakPolarHBondContact O-CB 3.24Å; F252-V256 PolarHBondContact O-N 2.77Å; F252-A257 HydrophobicContact CD1-CB 4.21Å; F252-A257 HydrophobicContact CE1-CB 4.2Å; F252-A257 PolarHBondContact O-N 2.93Å; F252-L293 HydrophobicContact CB-CD2 4.21Å; F252-L293 HydrophobicContact CD1-CD1 3.77Å; F252-L293 HydrophobicContact CD1-CD2 3.74Å; F252-L293 HydrophobicContact CD1-CG 4.44Å; F252-L293 HydrophobicContact CE1-CD1 3.93Å; F252-L293 HydrophobicContact CG-CD2 4.36Å
253	T	98.3	Very high	97.6	Very high	6 Å²	6	44.5 Å²	44.5	4%	0.037	21%	0.209	C	C	.	.	I	π-helix	trans	-56.3	-54.4	177.1	-54.7	0	0	0	0	110.7	I249 K250 L251 A257 E258 L293 W297	I249-T253 PolarHBondContact O-N 3.35Å; I249-T253 PolarHBondContact O-OG1 3.12Å; K250-T253 WeakPolarHBondContact O-CB 3.46Å; K250-T253 PolarHBondContact O-N 2.96Å; K250-T253 VanDerWaalsContact O-N 3.14Å; L251-T253 VanDerWaalsContact C-N 3.3Å; L251-T253 PolarHBondContact O-N 2.96Å; T253-A257 PolarHBondContact O-N 3.04Å; T253-E258 HydrophobicContact CG2-CG 4.41Å; T253-E258 WeakPolarHBondContact O-CB 3.5Å; T253-E258 WeakPolarHBondContact O-CG 3.48Å; T253-E258 PolarHBondContact O-N 3.39Å; T253-L293 VanDerWaalsContact OG1-CD2 3.27Å; T253-L293 WeakPolarHBondContact OG1-CD2 3.45Å; T253-W297 HydrophobicContact CG2-CH2 3.93Å; T253-W297 HydrophobicContact CG2-CZ2 4.3Å
254	E	98.2	Very high	97.5	Very high	72 Å²	72	42.3 Å²	42.3	34%	0.336	20%	0.198	S	C	.	.	I	π-helix	trans	-75.3	-43	-174.4	-66.1	177.6	163.8	0	0	113.2	K250	K250-E254 WeakPolarHBondContact CE-OE1 3.36Å; K250-E254 HydrophobicContact CG-CG 4.26Å; K250-E254 IonicContact NZ-OE1 3.1Å; K250-E254 WeakPolarHBondContact O-CG 3.37Å; K250-E254 PolarHBondContact O-N 2.96Å
255	H	98.3	Very high	97.3	Very high	38 Å²	38	42.6 Å²	42.6	18%	0.176	20%	0.199	C	C	.	.	I	π-helix	trans	-87.2	-20	-172	-69.2	-81.8	0	0	0	113.9	T188 L191 E192 S195 L251 K259	T188-H255 WeakPolarHBondContact CG2-CE1 3.33Å; L191-H255 HydrophobicContact CB-CB 4.01Å; E192-H255 IonicContact OE1-CE1 2.85Å; E192-H255 IonicContact OE1-ND1 2.77Å; S195-H255 WeakPolarHBondContact CB-O 3.47Å; S195-H255 PolarHBondContact OG-O 3.15Å; L251-H255 WeakPolarHBondContact O-CB 3.46Å; L251-H255 PolarHBondContact O-CD2 2.85Å; L251-H255 PolarHBondContact O-N 3.14Å; H255-K259 WeakPolarHBondContact O-CD 3.45Å; H255-K259 WeakPolarHBondContact O-CE 3.35Å; H255-K259 PolarHBondContact O-NZ 3Å
256	V	98.2	Very high	97.2	Very high	0 Å²	0	41.8 Å²	41.8	0%	0	20%	0.203	C	C	.	.	I	π-helix	trans	-124.2	-67.6	-177.9	-173.4	0	0	0	0	110.9	L191 L198 F210 F252 E258 K259 H260	L191-V256 HydrophobicContact CB-CG2 3.91Å; L191-V256 HydrophobicContact CD2-CG2 3.89Å; L191-V256 HydrophobicContact CG-CG2 4.44Å; L198-V256 HydrophobicContact CD1-CG1 3.76Å; F210-V256 HydrophobicContact CE2-CG1 4.4Å; F252-V256 HydrophobicContact CD1-CB 4.27Å; F252-V256 HydrophobicContact CD2-CB 4.38Å; F252-V256 HydrophobicContact CD2-CG2 4.23Å; F252-V256 HydrophobicContact CE1-CB 4.13Å; F252-V256 HydrophobicContact CE1-CG1 4.1Å; F252-V256 HydrophobicContact CE2-CB 4.25Å; F252-V256 HydrophobicContact CE2-CG1 4.2Å; F252-V256 HydrophobicContact CE2-CG2 4.26Å; F252-V256 HydrophobicContact CG-CB 4.39Å; F252-V256 HydrophobicContact CZ-CB 4.12Å; F252-V256 HydrophobicContact CZ-CG1 3.81Å; F252-V256 WeakPolarHBondContact O-CA 3.5Å; F252-V256 WeakPolarHBondContact O-CB 3.24Å; F252-V256 PolarHBondContact O-N 2.77Å; V256-E258 PolarHBondContact O-N 2.85Å; V256-K259 PolarHBondContact O-N 2.88Å; V256-K259 VanDerWaalsContact O-N 3.17Å; V256-H260 PolarHBondContact O-CD2 2.91Å; V256-H260 PolarHBondContact O-N 3.36Å
257	A	97.4	Very high	97	Very high	0 Å²	0	39 Å²	39	0%	0	19%	0.187	C	C	.	.	I	π-helix	trans	-63.8	-44.6	-164.9	0	0	0	0	0	113.2	F210 F252 T253 K259 H260 I261 L293 W297	F210-A257 HydrophobicContact CZ-CB 4.47Å; F252-A257 HydrophobicContact CD1-CB 4.21Å; F252-A257 HydrophobicContact CE1-CB 4.2Å; F252-A257 PolarHBondContact O-N 2.93Å; T253-A257 PolarHBondContact O-N 3.04Å; A257-K259 PolarHBondContact O-N 3.42Å; A257-H260 CarbonylContact O-C 3.53Å; A257-H260 PolarHBondContact O-N 3.34Å; A257-I261 WeakPolarHBondContact O-CB 3.44Å; A257-I261 PolarHBondContact O-N 2.84Å; A257-L293 HydrophobicContact CB-CD1 3.85Å; A257-W297 HydrophobicContact CB-CH2 3.53Å; A257-W297 HydrophobicContact CB-CZ3 4.04Å
258	E	96.7	Very high	96.8	Very high	72 Å²	72	38.2 Å²	38.2	34%	0.336	18%	0.183	S	C	.	.	H	α-helix	trans	-58.7	-34.9	177.5	-79.8	-173.2	157.7	0	0	113.4	T253 V256 H260 R294 W297	T253-E258 HydrophobicContact CG2-CG 4.41Å; T253-E258 WeakPolarHBondContact O-CB 3.5Å; T253-E258 WeakPolarHBondContact O-CG 3.48Å; T253-E258 PolarHBondContact O-N 3.39Å; V256-E258 PolarHBondContact O-N 2.85Å; E258-H260 VanDerWaalsContact C-N 3.29Å; E258-H260 PolarHBondContact O-N 3.3Å; E258-R294 IonicContact OE1-CZ 2.81Å; E258-R294 IonicContact OE1-NH1 2.72Å; E258-R294 PolarHBondContact OE1-NH1 2.94Å; E258-R294 IonicContact OE1-NH2 2.67Å; E258-R294 PolarHBondContact OE1-NH2 3.46Å; E258-W297 HydrophobicContact CG-CZ2 4.06Å
259	K	97.1	Very high	96.5	Very high	107 Å²	107	41.6 Å²	41.6	47%	0.465	20%	0.201	S	C	.	.	H	α-helix	trans	-75.1	-23.4	-180	-60.2	-179.5	-171.4	160	0	112.5	H255 V256 A257	H255-K259 WeakPolarHBondContact O-CD 3.45Å; H255-K259 WeakPolarHBondContact O-CE 3.35Å; H255-K259 PolarHBondContact O-NZ 3Å; V256-K259 PolarHBondContact O-N 2.88Å; V256-K259 VanDerWaalsContact O-N 3.17Å; A257-K259 PolarHBondContact O-N 3.42Å
260	H	97	Very high	96.3	Very high	6 Å²	6	45.8 Å²	45.8	3%	0.028	22%	0.22	C	C	.	.	H	α-helix	trans	-109.7	-13	-172.9	-64.7	-55.5	0	0	0	113.4	S195 Y206 F210 V256 A257 E258 Y262 S263 L264	S195-H260 WeakPolarHBondContact CA-NE2 3.1Å; S195-H260 PolarHBondContact O-CE1 2.89Å; S195-H260 VanDerWaalsContact O-CE1 3.3Å; S195-H260 PolarHBondContact O-NE2 3.41Å; S195-H260 PolarHBondContact OG-NE2 3.36Å; Y206-H260 WeakPolarHBondContact OH-CB 3.32Å; Y206-H260 VanDerWaalsContact OH-CG 3.29Å; Y206-H260 PolarHBondContact OH-ND1 3.46Å; F210-H260 HydrophobicContact CD2-CB 4.34Å; F210-H260 HydrophobicContact CE2-CB 4.12Å; V256-H260 PolarHBondContact O-CD2 2.91Å; V256-H260 PolarHBondContact O-N 3.36Å; A257-H260 CarbonylContact O-C 3.53Å; A257-H260 PolarHBondContact O-N 3.34Å; E258-H260 VanDerWaalsContact C-N 3.29Å; E258-H260 PolarHBondContact O-N 3.3Å; H260-Y262 VanDerWaalsContact C-N 3.35Å; H260-Y262 PolarHBondContact O-N 3.17Å; H260-S263 PolarHBondContact O-N 3.49Å; H260-S263 PolarHBondContact O-OG 2.9Å; H260-L264 WeakPolarHBondContact O-CB 3.4Å; H260-L264 PolarHBondContact O-N 3.49Å
261	I	96.3	Very high	95.9	Very high	3 Å²	3	40.8 Å²	40.8	2%	0.015	20%	0.2	C	C	.	.	H	α-helix	trans	-60.3	-41.6	-173.7	-165.7	62.7	0	0	0	112.8	A257 S263 L264 M265 L290 W297 M300	A257-I261 WeakPolarHBondContact O-CB 3.44Å; A257-I261 PolarHBondContact O-N 2.84Å; I261-S263 VanDerWaalsContact C-N 3.34Å; I261-S263 PolarHBondContact O-N 3.3Å; I261-L264 PolarHBondContact O-N 3.21Å; I261-M265 HydrophobicContact CD1-CE 3.56Å; I261-M265 HydrophobicContact CG1-CE 3.97Å; I261-M265 WeakPolarHBondContact O-CB 3.39Å; I261-M265 PolarHBondContact O-N 3.3Å; I261-L290 HydrophobicContact CD1-CD1 3.95Å; I261-L290 HydrophobicContact CD1-CD2 3.83Å; I261-W297 HydrophobicContact CD1-CD2 4.07Å; I261-W297 HydrophobicContact CD1-CE3 4.12Å; I261-W297 HydrophobicContact CD1-CG 4.4Å; I261-W297 HydrophobicContact CG1-CD2 4.11Å; I261-W297 HydrophobicContact CG1-CG 4.26Å; I261-M300 HydrophobicContact CG1-SD 4.06Å
262	Y	94.8	Very high	95.4	Very high	179 Å²	179	43.3 Å²	43.3	70%	0.702	21%	0.211	S	C	*	.	H	α-helix	trans	-72.1	-26.1	-177.9	-66.1	-72.9	0	0	0	113.6	H260 P266 M300	H260-Y262 VanDerWaalsContact C-N 3.35Å; H260-Y262 PolarHBondContact O-N 3.17Å; Y262-P266 WeakPolarHBondContact O-CD 3.25Å; Y262-P266 WeakPolarHBondContact O-CG 3.2Å; Y262-M300 HydrophobicContact CD1-CE 3.84Å; Y262-M300 HydrophobicContact CE1-CE 3.85Å
263	S	94.2	Very high	94.9	Very high	54 Å²	54	47.7 Å²	47.7	38%	0.378	24%	0.242	S	C	.	.	H	α-helix	trans	-85.6	-33.6	171.6	49.3	0	0	0	0	112.2	Y206 H260 I261 L267	Y206-S263 PolarHBondContact OH-OG 3.23Å; H260-S263 PolarHBondContact O-N 3.49Å; H260-S263 PolarHBondContact O-OG 2.9Å; I261-S263 VanDerWaalsContact C-N 3.34Å; I261-S263 PolarHBondContact O-N 3.3Å; S263-L267 WeakPolarHBondContact O-CD1 3.44Å; S263-L267 WeakPolarHBondContact O-CG 3.27Å
264	L	95.8	Very high	94.3	Very high	0 Å²	0	49.6 Å²	49.6	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-74	-45.2	-177.9	-177.6	66	0	0	0	112.1	Y206 I207 F210 H260 I261 L267 L268 I286 L290	Y206-L264 HydrophobicContact CD1-CD1 4.12Å; Y206-L264 HydrophobicContact CE1-CB 4.28Å; Y206-L264 HydrophobicContact CE1-CD1 4.16Å; I207-L264 HydrophobicContact CG1-CD1 4.26Å; F210-L264 HydrophobicContact CB-CD1 4.36Å; F210-L264 HydrophobicContact CD1-CD1 4.45Å; F210-L264 HydrophobicContact CD1-CD2 3.52Å; F210-L264 HydrophobicContact CD2-CD2 4.14Å; F210-L264 HydrophobicContact CE1-CD2 3.47Å; F210-L264 VanDerWaalsContact CE1-CD2 3.47Å; F210-L264 HydrophobicContact CE2-CD2 4.11Å; F210-L264 HydrophobicContact CG-CD1 4.34Å; F210-L264 HydrophobicContact CG-CD2 3.86Å; F210-L264 HydrophobicContact CZ-CD2 3.79Å; H260-L264 WeakPolarHBondContact O-CB 3.4Å; H260-L264 PolarHBondContact O-N 3.49Å; I261-L264 PolarHBondContact O-N 3.21Å; L264-L267 WeakPolarHBondContact O-CB 3.2Å; L264-L267 PolarHBondContact O-N 3.35Å; L264-L267 VanDerWaalsContact O-N 3.11Å; L264-L268 HydrophobicContact CD1-CD1 4.47Å; L264-L268 HydrophobicContact CD1-CD2 4.29Å; L264-L268 HydrophobicContact CD1-CG 4.2Å; L264-L268 HydrophobicContact CD2-CD1 4.29Å; L264-L268 HydrophobicContact CG-CD1 3.9Å; L264-L268 HydrophobicContact CG-CG 4.06Å; L264-L268 WeakPolarHBondContact O-CG 3.48Å; L264-L268 PolarHBondContact O-N 2.96Å; L264-I286 HydrophobicContact CD2-CG2 4.15Å; L264-L290 HydrophobicContact CD2-CD1 4.3Å
265	M	95.3	Very high	93.6	Very high	6 Å²	6	51.2 Å²	51.2	3%	0.03	27%	0.27	C	S	.	.	H	α-helix	trans	-58	-45.8	-172.9	-159.2	72.4	73.3	0	0	113.3	I261 L267 L268 L269 M300 A301 L304 F305	I261-M265 HydrophobicContact CD1-CE 3.56Å; I261-M265 HydrophobicContact CG1-CE 3.97Å; I261-M265 WeakPolarHBondContact O-CB 3.39Å; I261-M265 PolarHBondContact O-N 3.3Å; M265-L267 VanDerWaalsContact C-N 3.33Å; M265-L267 PolarHBondContact O-N 2.75Å; M265-L268 PolarHBondContact O-N 2.89Å; M265-L269 WeakPolarHBondContact O-CG 3.48Å; M265-L269 PolarHBondContact O-N 3.11Å; M265-L269 VanDerWaalsContact O-N 3.09Å; M265-M300 HydrophobicContact CB-CE 4.38Å; M265-M300 HydrophobicContact CE-CB 3.9Å; M265-M300 HydrophobicContact CE-CE 4.41Å; M265-M300 HydrophobicContact CE-CG 4.43Å; M265-M300 HydrophobicContact CE-SD 3.86Å; M265-M300 HydrophobicContact CG-CB 4.36Å; M265-M300 HydrophobicContact CG-CE 4.44Å; M265-A301 HydrophobicContact CG-CB 4.34Å; M265-A301 HydrophobicContact SD-CB 3.94Å; M265-L304 HydrophobicContact SD-CD2 4.43Å; M265-F305 HydrophobicContact CE-CE2 4.18Å; M265-F305 HydrophobicContact SD-CE2 4.23Å
266	P	94.4	Very high	93	Very high	71 Å²	71	59.3 Å²	59.3	46%	0.461	31%	0.305	S	S	.	.	H	α-helix	trans	-61	-40.7	175.5	-23.2	35.3	0	0	0	112.8	Y262 L268 L269 E270	Y262-P266 WeakPolarHBondContact O-CD 3.25Å; Y262-P266 WeakPolarHBondContact O-CG 3.2Å; P266-L268 VanDerWaalsContact C-N 3.33Å; P266-L268 PolarHBondContact O-N 3.47Å; P266-L269 PolarHBondContact O-N 2.91Å; P266-E270 PolarHBondContact O-N 3.42Å
267	L	94.2	Very high	92.4	Very high	43 Å²	43	64.1 Å²	64.1	23%	0.225	33%	0.328	C	S	.	.	H	α-helix	trans	-64.4	-37.6	178	-63.3	173.9	0	0	0	111.7	Y206 I207 S263 L264 M265 A271	Y206-L267 HydrophobicContact CD1-CD1 3.81Å; Y206-L267 HydrophobicContact CG-CD1 4.19Å; I207-L267 HydrophobicContact CD1-CB 3.98Å; I207-L267 HydrophobicContact CG1-CB 4.1Å; S263-L267 WeakPolarHBondContact O-CD1 3.44Å; S263-L267 WeakPolarHBondContact O-CG 3.27Å; L264-L267 WeakPolarHBondContact O-CB 3.2Å; L264-L267 PolarHBondContact O-N 3.35Å; L264-L267 VanDerWaalsContact O-N 3.11Å; M265-L267 VanDerWaalsContact C-N 3.33Å; M265-L267 PolarHBondContact O-N 2.75Å; L267-A271 WeakPolarHBondContact O-CB 3.43Å; L267-A271 PolarHBondContact O-N 3.24Å
268	L	94.1	Very high	92.2	Very high	1 Å²	1	65.5 Å²	65.5	1%	0.005	34%	0.336	C	S	.	.	H	α-helix	trans	-66.4	-39	175.4	-64.5	174.9	0	0	0	112.2	I207 L264 M265 P266 Q272 M283 I286 L290 L304	I207-L268 HydrophobicContact CD1-CD2 4.24Å; I207-L268 HydrophobicContact CG1-CD2 4.3Å; I207-L268 HydrophobicContact CG2-CD2 3.93Å; L264-L268 HydrophobicContact CD1-CD1 4.47Å; L264-L268 HydrophobicContact CD1-CD2 4.29Å; L264-L268 HydrophobicContact CD1-CG 4.2Å; L264-L268 HydrophobicContact CD2-CD1 4.29Å; L264-L268 HydrophobicContact CG-CD1 3.9Å; L264-L268 HydrophobicContact CG-CG 4.06Å; L264-L268 WeakPolarHBondContact O-CG 3.48Å; L264-L268 PolarHBondContact O-N 2.96Å; M265-L268 PolarHBondContact O-N 2.89Å; P266-L268 VanDerWaalsContact C-N 3.33Å; P266-L268 PolarHBondContact O-N 3.47Å; L268-Q272 WeakPolarHBondContact O-CB 3.22Å; L268-Q272 PolarHBondContact O-N 3.38Å; L268-M283 HydrophobicContact CB-CE 4.47Å; L268-M283 HydrophobicContact CB-SD 4.24Å; L268-M283 HydrophobicContact CD2-CE 4.15Å; L268-M283 HydrophobicContact CD2-SD 3.74Å; L268-M283 HydrophobicContact CG-SD 4.48Å; L268-I286 HydrophobicContact CD1-CG2 3.85Å; L268-I286 HydrophobicContact CD2-CD1 3.96Å; L268-I286 HydrophobicContact CD2-CG2 4.22Å; L268-L290 HydrophobicContact CD1-CD1 4.23Å; L268-L304 HydrophobicContact CB-CD2 3.9Å; L268-L304 HydrophobicContact CD1-CD2 4.37Å
269	L	93.4	Very high	91.9	Very high	71 Å²	71	65.6 Å²	65.6	37%	0.372	34%	0.342	S	S	.	.	H	α-helix	trans	-67.6	-42.4	176.7	-70.3	173.4	0	0	0	111.6	M265 P266 Q272 S273 A301 L304	M265-L269 WeakPolarHBondContact O-CG 3.48Å; M265-L269 PolarHBondContact O-N 3.11Å; M265-L269 VanDerWaalsContact O-N 3.09Å; P266-L269 PolarHBondContact O-N 2.91Å; L269-Q272 PolarHBondContact O-N 3.48Å; L269-S273 PolarHBondContact O-N 3.37Å; L269-A301 HydrophobicContact CD2-CB 4.12Å; L269-L304 HydrophobicContact CD2-CB 4.28Å; L269-L304 HydrophobicContact CD2-CD2 4.39Å
270	E	93	Very high	91.6	Very high	108 Å²	108	65.4 Å²	65.4	51%	0.505	35%	0.352	S	S	.	.	H	α-helix	trans	-62	-50.6	174.1	-174.8	177.3	175.9	0	0	110.7	P266 Q272 S273 T274	P266-E270 PolarHBondContact O-N 3.42Å; E270-Q272 PolarHBondContact O-N 2.83Å; E270-Q272 VanDerWaalsContact O-N 3.13Å; E270-S273 WeakPolarHBondContact O-CA 3.45Å; E270-S273 PolarHBondContact O-N 3.35Å; E270-S273 PolarHBondContact O-OG 3.43Å; E270-T274 PolarHBondContact O-N 3.27Å; E270-T274 PolarHBondContact O-OG1 3.25Å; E270-T274 VanDerWaalsContact O-OG1 3.12Å
271	A	90.9	Very high	91.5	Very high	6 Å²	6	68.5 Å²	68.5	5%	0.05	37%	0.374	C	S	.	.	H	α-helix	trans	-59.1	-26.4	178.8	0	0	0	0	0	113.8	I207 L267 T274 V278 M283	I207-A271 HydrophobicContact CD1-CB 3.85Å; L267-A271 WeakPolarHBondContact O-CB 3.43Å; L267-A271 PolarHBondContact O-N 3.24Å; A271-T274 VanDerWaalsContact CA-OG1 3.27Å; A271-T274 WeakPolarHBondContact CA-OG1 3.48Å; A271-T274 PolarHBondContact O-OG1 3.44Å; A271-V278 HydrophobicContact CB-CB 4.29Å; A271-V278 HydrophobicContact CB-CG2 3.64Å; A271-M283 HydrophobicContact CB-CE 4.03Å
272	Q	87.4	Confident	91.4	Very high	66 Å²	66	69.5 Å²	69.5	31%	0.308	38%	0.38	S	S	.	.	H	α-helix	trans	-72.6	-31.2	174.1	174.2	174.6	105	0	0	112.5	L268 L269 E270 T274 K307	L268-Q272 WeakPolarHBondContact O-CB 3.22Å; L268-Q272 PolarHBondContact O-N 3.38Å; L269-Q272 PolarHBondContact O-N 3.48Å; E270-Q272 PolarHBondContact O-N 2.83Å; E270-Q272 VanDerWaalsContact O-N 3.13Å; Q272-T274 VanDerWaalsContact C-N 3.33Å; Q272-K307 VanDerWaalsContact NE2-NZ 3.16Å
273	S	87.3	Confident	91.4	Very high	92 Å²	92	61.5 Å²	61.5	64%	0.643	35%	0.349	S	S	*	.	H	α-helix	trans	-82.8	-13.5	-179.8	71.1	0	0	0	0	113.2	L269 E270	L269-S273 PolarHBondContact O-N 3.37Å; E270-S273 WeakPolarHBondContact O-CA 3.45Å; E270-S273 PolarHBondContact O-N 3.35Å; E270-S273 PolarHBondContact O-OG 3.43Å
274	T	86.2	Confident	91.4	Very high	46 Å²	46	59.6 Å²	59.6	28%	0.282	34%	0.336	S	S	.	.	S	Bend	trans	-109.5	109.5	-177.3	47.6	0	0	0	0	110.9	E270 A271 Q272 F276 Q277	E270-T274 PolarHBondContact O-N 3.27Å; E270-T274 PolarHBondContact O-OG1 3.25Å; E270-T274 VanDerWaalsContact O-OG1 3.12Å; A271-T274 VanDerWaalsContact CA-OG1 3.27Å; A271-T274 WeakPolarHBondContact CA-OG1 3.48Å; A271-T274 PolarHBondContact O-OG1 3.44Å; Q272-T274 VanDerWaalsContact C-N 3.33Å; T274-F276 PolarHBondContact O-N 3Å; T274-Q277 PolarHBondContact O-N 3.3Å; T274-Q277 WeakPolarHBondContact OG1-CB 3.37Å; T274-Q277 PolarHBondContact OG1-OE1 2.89Å
275	P	83.5	Confident	91.5	Very high	107 Å²	107	63.1 Å²	63.1	70%	0.695	36%	0.356	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57	137.5	178.8	-24.8	34	0	0	0	112.3	Q277	P275-Q277 PolarHBondContact O-N 3.31Å; P275-Q277 VanDerWaalsContact O-N 3.15Å
276	F	84.9	Confident	91.5	Very high	207 Å²	207	62.9 Å²	62.9	91%	0.908	35%	0.354	S	S	*	.	T	Hydrogen-bonded Turn	trans	66.1	2.5	174.8	-44.4	-71	0	0	0	117.1	T274	T274-F276 PolarHBondContact O-N 3Å
277	Q	87.1	Confident	91.6	Very high	102 Å²	102	59.5 Å²	59.5	48%	0.477	33%	0.332	S	S	.	.	S	Bend	trans	-66.4	-39.9	176.7	-171.4	174.1	16.2	0	0	112	T274 P275	T274-Q277 PolarHBondContact O-N 3.3Å; T274-Q277 WeakPolarHBondContact OG1-CB 3.37Å; T274-Q277 PolarHBondContact OG1-OE1 2.89Å; P275-Q277 PolarHBondContact O-N 3.31Å; P275-Q277 VanDerWaalsContact O-N 3.15Å
278	V	91.6	Very high	91.7	Very high	29 Å²	29	62.6 Å²	62.6	18%	0.176	34%	0.344	C	S	.	.	S	Bend	trans	-130.3	136.7	176.7	178	0	0	0	0	108.8	I207 A271 T282 M283	I207-V278 HydrophobicContact CB-CG2 4.49Å; I207-V278 HydrophobicContact CD1-CG2 3.79Å; I207-V278 HydrophobicContact CG2-CG1 4.16Å; I207-V278 HydrophobicContact CG2-CG2 4.05Å; A271-V278 HydrophobicContact CB-CB 4.29Å; A271-V278 HydrophobicContact CB-CG2 3.64Å; V278-T282 HydrophobicContact CG1-CG2 3.75Å; V278-M283 HydrophobicContact CB-CE 4.42Å; V278-M283 HydrophobicContact CG1-CB 4.37Å; V278-M283 HydrophobicContact CG1-CE 4.36Å
279	T	91.8	Very high	91.8	Very high	74 Å²	74	63 Å²	63	45%	0.454	35%	0.349	S	S	.	.			trans	-66.7	144.3	177	61	0	0	0	0	110.5	S281 T282 M283	T279-S281 PolarHBondContact O-N 2.92Å; T279-S281 VanDerWaalsContact O-N 3.15Å; T279-S281 PolarHBondContact OG1-OG 3.48Å; T279-T282 PolarHBondContact O-N 3.03Å; T279-T282 VanDerWaalsContact O-N 3.13Å; T279-T282 WeakPolarHBondContact OG1-CB 3.4Å; T279-T282 PolarHBondContact OG1-N 3.45Å; T279-T282 PolarHBondContact OG1-OG1 3.06Å; T279-M283 PolarHBondContact O-N 2.9Å; T279-M283 VanDerWaalsContact O-N 3.09Å
280	P	91.3	Very high	92	Very high	103 Å²	103	59.6 Å²	59.6	67%	0.669	33%	0.331	S	S	*	.	H	α-helix	trans	-56.6	-31.7	177.9	-27.5	35.3	0	0	0	113.7	A284	P280-A284 VanDerWaalsContact O-CB 3.29Å; P280-A284 WeakPolarHBondContact O-CB 3.33Å; P280-A284 PolarHBondContact O-N 3.11Å
281	S	93	Very high	92.2	Very high	71 Å²	71	58.8 Å²	58.8	50%	0.497	32%	0.324	S	S	.	.	H	α-helix	trans	-66.6	-46.3	176.3	51.8	0	0	0	0	112.4	T279 M283 A284 N285	T279-S281 PolarHBondContact O-N 2.92Å; T279-S281 VanDerWaalsContact O-N 3.15Å; T279-S281 PolarHBondContact OG1-OG 3.48Å; S281-M283 VanDerWaalsContact C-N 3.34Å; S281-M283 PolarHBondContact O-N 3.23Å; S281-A284 PolarHBondContact O-N 3.08Å; S281-N285 WeakPolarHBondContact O-CB 3.23Å; S281-N285 PolarHBondContact O-N 3.33Å; S281-N285 PolarHBondContact O-ND2 3.31Å; S281-N285 PolarHBondContact O-OD1 2.92Å
282	T	95.1	Very high	92.4	Very high	23 Å²	23	62.6 Å²	62.6	14%	0.141	35%	0.346	C	S	.	.	H	α-helix	trans	-60.6	-45.8	175.7	-66.2	0	0	0	0	110.8	I207 N211 V278 T279 A284 N285 I286	I207-T282 HydrophobicContact CG2-CG2 4.22Å; N211-T282 HydrophobicContact CB-CG2 3.9Å; V278-T282 HydrophobicContact CG1-CG2 3.75Å; T279-T282 PolarHBondContact O-N 3.03Å; T279-T282 VanDerWaalsContact O-N 3.13Å; T279-T282 WeakPolarHBondContact OG1-CB 3.4Å; T279-T282 PolarHBondContact OG1-N 3.45Å; T279-T282 PolarHBondContact OG1-OG1 3.06Å; T282-A284 PolarHBondContact O-N 2.96Å; T282-N285 PolarHBondContact O-N 3.12Å; T282-I286 HydrophobicContact CG2-CD1 4.01Å; T282-I286 WeakPolarHBondContact O-CG1 3.41Å; T282-I286 PolarHBondContact O-N 2.68Å
283	M	94.9	Very high	92.8	Very high	11 Å²	11	60.2 Å²	60.2	5%	0.054	34%	0.336	C	S	.	.	H	α-helix	trans	-60.3	-46.6	177	-171.6	66	73	0	0	111.5	L268 A271 V278 T279 S281 N285 I286 V287 L304 F308	L268-M283 HydrophobicContact CB-CE 4.47Å; L268-M283 HydrophobicContact CB-SD 4.24Å; L268-M283 HydrophobicContact CD2-CE 4.15Å; L268-M283 HydrophobicContact CD2-SD 3.74Å; L268-M283 HydrophobicContact CG-SD 4.48Å; A271-M283 HydrophobicContact CB-CE 4.03Å; V278-M283 HydrophobicContact CB-CE 4.42Å; V278-M283 HydrophobicContact CG1-CB 4.37Å; V278-M283 HydrophobicContact CG1-CE 4.36Å; T279-M283 PolarHBondContact O-N 2.9Å; T279-M283 VanDerWaalsContact O-N 3.09Å; S281-M283 VanDerWaalsContact C-N 3.34Å; S281-M283 PolarHBondContact O-N 3.23Å; M283-N285 PolarHBondContact O-N 3.44Å; M283-I286 PolarHBondContact O-N 3.04Å; M283-V287 HydrophobicContact CG-CG2 4.45Å; M283-V287 WeakPolarHBondContact O-CB 3.5Å; M283-V287 VanDerWaalsContact O-CG2 3.27Å; M283-V287 WeakPolarHBondContact O-CG2 3.4Å; M283-V287 PolarHBondContact O-N 3.39Å; M283-V287 HydrophobicContact SD-CG2 4.39Å; M283-L304 HydrophobicContact CG-CD1 4.44Å; M283-L304 HydrophobicContact SD-CD1 4Å; M283-F308 HydrophobicContact CB-CE1 4.45Å; M283-F308 HydrophobicContact CB-CE2 4.31Å; M283-F308 HydrophobicContact CB-CZ 3.84Å; M283-F308 HydrophobicContact CG-CD2 4.39Å; M283-F308 HydrophobicContact CG-CE1 4.36Å; M283-F308 HydrophobicContact CG-CE2 3.4Å; M283-F308 HydrophobicContact CG-CZ 3.38Å
284	A	94.7	Very high	93.2	Very high	14 Å²	14	59 Å²	59	12%	0.116	32%	0.317	C	S	.	.	H	α-helix	trans	-60.8	-43.1	177.9	0	0	0	0	0	112.3	P280 S281 T282 V287 K288 F308	P280-A284 VanDerWaalsContact O-CB 3.29Å; P280-A284 WeakPolarHBondContact O-CB 3.33Å; P280-A284 PolarHBondContact O-N 3.11Å; S281-A284 PolarHBondContact O-N 3.08Å; T282-A284 PolarHBondContact O-N 2.96Å; A284-V287 PolarHBondContact O-N 2.98Å; A284-K288 VanDerWaalsContact O-CB 3.26Å; A284-K288 WeakPolarHBondContact O-CB 3.36Å; A284-K288 WeakPolarHBondContact O-CG 3.3Å; A284-K288 PolarHBondContact O-N 3.04Å; A284-F308 HydrophobicContact CB-CD1 3.51Å; A284-F308 HydrophobicContact CB-CE1 3.89Å; A284-F308 HydrophobicContact CB-CG 4.25Å
285	N	96.4	Very high	93.6	Very high	75 Å²	75	60.2 Å²	60.2	40%	0.401	33%	0.326	S	S	.	.	H	α-helix	trans	-64.3	-44.9	-179.8	-71.5	-9.5	0	0	0	111.7	N211 S281 T282 M283 G289	N211-N285 VanDerWaalsContact OD1-CB 3.3Å; N211-N285 WeakPolarHBondContact OD1-CB 3.39Å; S281-N285 WeakPolarHBondContact O-CB 3.23Å; S281-N285 PolarHBondContact O-N 3.33Å; S281-N285 PolarHBondContact O-ND2 3.31Å; S281-N285 PolarHBondContact O-OD1 2.92Å; T282-N285 PolarHBondContact O-N 3.12Å; M283-N285 PolarHBondContact O-N 3.44Å; N285-G289 PolarHBondContact O-N 3.43Å
286	I	96.9	Very high	94.1	Very high	0 Å²	0	61.6 Å²	61.6	0%	0	32%	0.323	C	S	.	.	H	α-helix	trans	-62.6	-51.7	176	-65.2	171.3	0	0	0	110.1	I207 F210 N211 L264 L268 T282 M283 K288 G289 L290	I207-I286 HydrophobicContact CG2-CD1 3.4Å; F210-I286 HydrophobicContact CD1-CG1 4.48Å; F210-I286 HydrophobicContact CD1-CG2 4.39Å; F210-I286 HydrophobicContact CE1-CG2 4.35Å; N211-I286 HydrophobicContact CB-CD1 3.94Å; N211-I286 HydrophobicContact CB-CG1 3.76Å; L264-I286 HydrophobicContact CD2-CG2 4.15Å; L268-I286 HydrophobicContact CD1-CG2 3.85Å; L268-I286 HydrophobicContact CD2-CD1 3.96Å; L268-I286 HydrophobicContact CD2-CG2 4.22Å; T282-I286 HydrophobicContact CG2-CD1 4.01Å; T282-I286 WeakPolarHBondContact O-CG1 3.41Å; T282-I286 PolarHBondContact O-N 2.68Å; M283-I286 PolarHBondContact O-N 3.04Å; I286-K288 PolarHBondContact O-N 3.21Å; I286-G289 PolarHBondContact O-N 2.97Å; I286-L290 HydrophobicContact CG2-CD1 3.77Å; I286-L290 HydrophobicContact CG2-CG 4.05Å; I286-L290 WeakPolarHBondContact O-CB 3.42Å; I286-L290 VanDerWaalsContact O-CG 3.26Å; I286-L290 WeakPolarHBondContact O-CG 3.45Å; I286-L290 PolarHBondContact O-N 2.91Å
287	V	96.4	Very high	94.5	Very high	0 Å²	0	52.7 Å²	52.7	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-60.1	-46.4	-177.1	169.8	0	0	0	0	111.3	M283 A284 L290 Y291 L304 F305 F308 I309	M283-V287 HydrophobicContact CG-CG2 4.45Å; M283-V287 WeakPolarHBondContact O-CB 3.5Å; M283-V287 VanDerWaalsContact O-CG2 3.27Å; M283-V287 WeakPolarHBondContact O-CG2 3.4Å; M283-V287 PolarHBondContact O-N 3.39Å; M283-V287 HydrophobicContact SD-CG2 4.39Å; A284-V287 PolarHBondContact O-N 2.98Å; V287-L290 PolarHBondContact O-N 3.14Å; V287-Y291 WeakPolarHBondContact O-CB 3.41Å; V287-Y291 PolarHBondContact O-N 3.02Å; V287-L304 HydrophobicContact CG2-CD1 4.35Å; V287-L304 HydrophobicContact CG2-CD2 4.36Å; V287-L304 HydrophobicContact CG2-CG 4.07Å; V287-F305 HydrophobicContact CG1-CB 4.31Å; V287-F305 HydrophobicContact CG1-CD1 3.62Å; V287-F305 HydrophobicContact CG1-CE1 4.07Å; V287-F305 HydrophobicContact CG1-CG 3.95Å; V287-F308 HydrophobicContact CB-CB 4.34Å; V287-F308 HydrophobicContact CB-CD2 4.11Å; V287-F308 HydrophobicContact CB-CG 4.46Å; V287-F308 HydrophobicContact CG1-CB 3.96Å; V287-F308 HydrophobicContact CG1-CD2 4.09Å; V287-F308 HydrophobicContact CG1-CG 4.42Å; V287-F308 HydrophobicContact CG2-CD2 3.92Å; V287-F308 HydrophobicContact CG2-CE2 4.34Å; V287-I309 HydrophobicContact CG1-CD1 4.1Å; V287-I309 HydrophobicContact CG1-CG1 4.42Å
288	K	95.8	Very high	94.9	Very high	108 Å²	108	48.9 Å²	48.9	47%	0.47	27%	0.267	S	S	.	.	H	α-helix	trans	-63.8	-43.1	176.4	-71.2	175.3	-178.9	-174.8	0	111.8	A284 I286 Y291 T292 F308 I309	A284-K288 VanDerWaalsContact O-CB 3.26Å; A284-K288 WeakPolarHBondContact O-CB 3.36Å; A284-K288 WeakPolarHBondContact O-CG 3.3Å; A284-K288 PolarHBondContact O-N 3.04Å; I286-K288 PolarHBondContact O-N 3.21Å; K288-Y291 WeakPolarHBondContact O-CB 3.42Å; K288-Y291 PolarHBondContact O-N 3.19Å; K288-T292 PolarHBondContact O-N 3.48Å; K288-T292 PolarHBondContact O-OG1 2.96Å; K288-T292 VanDerWaalsContact O-OG1 3.06Å; K288-F308 WeakPolarHBondContact CE-O 3.38Å; K288-I309 HydrophobicContact CG-CD1 4.48Å; K288-I309 HydrophobicContact CG-CG1 4.11Å
289	G	96.7	Very high	94.9	Very high	10 Å²	10	55.2 Å²	55.2	10%	0.103	29%	0.294	C	S	.	.	H	α-helix	trans	-68.9	-38.6	179.5	0	0	0	0	0	113	N285 I286 Y291 T292 L293	N285-G289 PolarHBondContact O-N 3.43Å; I286-G289 PolarHBondContact O-N 2.97Å; G289-Y291 VanDerWaalsContact C-N 3.31Å; G289-Y291 PolarHBondContact O-N 2.96Å; G289-T292 PolarHBondContact O-N 3.35Å; G289-L293 VanDerWaalsContact O-CG 3.23Å; G289-L293 WeakPolarHBondContact O-CG 3.3Å; G289-L293 PolarHBondContact O-N 3.37Å
290	L	97.1	Very high	94.9	Very high	0 Å²	0	55.2 Å²	55.2	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-60.3	-41.9	171.6	-71.8	179.4	0	0	0	111.2	F210 I261 L264 L268 I286 V287 L293 R294 W297 F305	F210-L290 HydrophobicContact CE1-CD2 4.15Å; F210-L290 HydrophobicContact CZ-CD2 4.1Å; I261-L290 HydrophobicContact CD1-CD1 3.95Å; I261-L290 HydrophobicContact CD1-CD2 3.83Å; L264-L290 HydrophobicContact CD2-CD1 4.3Å; L268-L290 HydrophobicContact CD1-CD1 4.23Å; I286-L290 HydrophobicContact CG2-CD1 3.77Å; I286-L290 HydrophobicContact CG2-CG 4.05Å; I286-L290 WeakPolarHBondContact O-CB 3.42Å; I286-L290 VanDerWaalsContact O-CG 3.26Å; I286-L290 WeakPolarHBondContact O-CG 3.45Å; I286-L290 PolarHBondContact O-N 2.91Å; V287-L290 PolarHBondContact O-N 3.14Å; L290-L293 HydrophobicContact CD2-CD1 4.48Å; L290-L293 PolarHBondContact O-N 3.27Å; L290-R294 CarbonylContact O-C 3.5Å; L290-R294 PolarHBondContact O-N 2.99Å; L290-W297 HydrophobicContact CB-CE3 4.11Å; L290-W297 HydrophobicContact CD2-CE3 3.93Å; L290-W297 HydrophobicContact CD2-CZ3 3.75Å; L290-F305 HydrophobicContact CB-CE1 4.22Å; L290-F305 HydrophobicContact CB-CZ 4.09Å; L290-F305 HydrophobicContact CD1-CZ 4.37Å
291	Y	96.1	Very high	95	Very high	90 Å²	90	50.5 Å²	50.5	35%	0.353	26%	0.26	S	S	.	.	H	α-helix	trans	-63.1	-43.4	175.4	-174.8	-99.8	0	0	0	112.3	V287 K288 G289 L293 R294 P295 V298 I309 I312	V287-Y291 WeakPolarHBondContact O-CB 3.41Å; V287-Y291 PolarHBondContact O-N 3.02Å; K288-Y291 WeakPolarHBondContact O-CB 3.42Å; K288-Y291 PolarHBondContact O-N 3.19Å; G289-Y291 VanDerWaalsContact C-N 3.31Å; G289-Y291 PolarHBondContact O-N 2.96Å; Y291-L293 VanDerWaalsContact C-N 3.32Å; Y291-L293 PolarHBondContact O-N 3.01Å; Y291-R294 CarbonylContact O-C 3.44Å; Y291-R294 PolarHBondContact O-N 3.36Å; Y291-P295 HydrophobicContact CD2-CB 4.18Å; Y291-P295 HydrophobicContact CE2-CB 3.81Å; Y291-P295 HydrophobicContact CE2-CG 4.47Å; Y291-P295 WeakPolarHBondContact O-CD 3.47Å; Y291-P295 WeakPolarHBondContact O-CG 3.36Å; Y291-V298 HydrophobicContact CD2-CG2 3.67Å; Y291-V298 HydrophobicContact CE2-CG2 3.92Å; Y291-I309 VanDerWaalsContact CB-CD1 3.44Å; Y291-I309 HydrophobicContact CD1-CD1 4.03Å; Y291-I309 HydrophobicContact CD2-CD1 4.03Å; Y291-I309 HydrophobicContact CG-CD1 3.57Å; Y291-I312 HydrophobicContact CD2-CD1 4.26Å; Y291-I312 HydrophobicContact CE2-CD1 4.23Å
292	T	95.5	Very high	94.9	Very high	86 Å²	86	49.4 Å²	49.4	53%	0.528	25%	0.251	S	S	.	.	H	α-helix	trans	-61.5	-38.1	175	-60.3	0	0	0	0	112.5	K288 G289	K288-T292 PolarHBondContact O-N 3.48Å; K288-T292 PolarHBondContact O-OG1 2.96Å; K288-T292 VanDerWaalsContact O-OG1 3.06Å; G289-T292 PolarHBondContact O-N 3.35Å
293	L	96.8	Very high	94.8	Very high	16 Å²	16	52.5 Å²	52.5	8%	0.084	27%	0.27	C	S	.	.	H	α-helix	trans	-70.7	-48.7	178.2	-71	166.5	0	0	0	111.7	L214 M218 I249 F252 T253 A257 G289 L290 Y291 W297	L214-L293 HydrophobicContact CD1-CD1 3.86Å; M218-L293 HydrophobicContact CE-CD1 4.5Å; M218-L293 HydrophobicContact CE-CD2 3.47Å; M218-L293 VanDerWaalsContact CE-CD2 3.47Å; M218-L293 HydrophobicContact CE-CG 3.84Å; I249-L293 HydrophobicContact CG2-CD2 4.06Å; F252-L293 HydrophobicContact CB-CD2 4.21Å; F252-L293 HydrophobicContact CD1-CD1 3.77Å; F252-L293 HydrophobicContact CD1-CD2 3.74Å; F252-L293 HydrophobicContact CD1-CG 4.44Å; F252-L293 HydrophobicContact CE1-CD1 3.93Å; F252-L293 HydrophobicContact CG-CD2 4.36Å; T253-L293 VanDerWaalsContact OG1-CD2 3.27Å; T253-L293 WeakPolarHBondContact OG1-CD2 3.45Å; A257-L293 HydrophobicContact CB-CD1 3.85Å; G289-L293 VanDerWaalsContact O-CG 3.23Å; G289-L293 WeakPolarHBondContact O-CG 3.3Å; G289-L293 PolarHBondContact O-N 3.37Å; L290-L293 HydrophobicContact CD2-CD1 4.48Å; L290-L293 PolarHBondContact O-N 3.27Å; Y291-L293 VanDerWaalsContact C-N 3.32Å; Y291-L293 PolarHBondContact O-N 3.01Å; L293-W297 HydrophobicContact CB-CH2 4.32Å; L293-W297 HydrophobicContact CB-CZ3 3.78Å; L293-W297 HydrophobicContact CD1-CZ3 4.28Å
294	R	95.4	Very high	94.6	Very high	68 Å²	68	52 Å²	52	26%	0.257	27%	0.268	S	S	.	.			trans	-155.6	108.9	178	-174.2	172.5	-64.3	167	4.5	111.3	E258 L290 Y291 E296 W297	E258-R294 IonicContact OE1-CZ 2.81Å; E258-R294 IonicContact OE1-NH1 2.72Å; E258-R294 PolarHBondContact OE1-NH1 2.94Å; E258-R294 IonicContact OE1-NH2 2.67Å; E258-R294 PolarHBondContact OE1-NH2 3.46Å; L290-R294 CarbonylContact O-C 3.5Å; L290-R294 PolarHBondContact O-N 2.99Å; Y291-R294 CarbonylContact O-C 3.44Å; Y291-R294 PolarHBondContact O-N 3.36Å; R294-E296 HydrophobicContact CG-CB 4.02Å; R294-E296 HydrophobicContact CG-CG 4.36Å; R294-E296 PolarHBondContact O-N 3.34Å; R294-W297 HydrophobicContact CB-CD2 3.82Å; R294-W297 HydrophobicContact CB-CE3 3.84Å; R294-W297 HydrophobicContact CB-CG 4.43Å; R294-W297 HydrophobicContact CB-CH2 4.1Å; R294-W297 HydrophobicContact CB-CZ2 4.09Å; R294-W297 HydrophobicContact CB-CZ3 3.99Å; R294-W297 HydrophobicContact CG-CD2 4.38Å; R294-W297 PolarHBondContact O-N 3.43Å
295	P	93.9	Very high	94.6	Very high	71 Å²	71	51.3 Å²	51.3	46%	0.461	26%	0.262	S	S	.	.	G	3₁₀ helix	trans	-60.7	-27.8	177.9	-26.9	35.6	0	0	0	114.2	Y291 W297 V298	Y291-P295 HydrophobicContact CD2-CB 4.18Å; Y291-P295 HydrophobicContact CE2-CB 3.81Å; Y291-P295 HydrophobicContact CE2-CG 4.47Å; Y291-P295 WeakPolarHBondContact O-CD 3.47Å; Y291-P295 WeakPolarHBondContact O-CG 3.36Å; P295-W297 PolarHBondContact O-N 3.17Å; P295-W297 VanDerWaalsContact O-N 3.14Å; P295-V298 VanDerWaalsContact O-CB 3.27Å; P295-V298 WeakPolarHBondContact O-CB 3.29Å; P295-V298 WeakPolarHBondContact O-CG2 3.29Å; P295-V298 PolarHBondContact O-N 3.08Å; P295-V298 VanDerWaalsContact O-N 3.1Å
296	E	93.9	Very high	94.5	Very high	136 Å²	136	49.6 Å²	49.6	64%	0.636	26%	0.256	S	S	*	.	G	3₁₀ helix	trans	-61.9	-23.7	-178	-59.7	-176.2	157.9	0	0	113.7	R294 V298 Q299	R294-E296 HydrophobicContact CG-CB 4.02Å; R294-E296 HydrophobicContact CG-CG 4.36Å; R294-E296 PolarHBondContact O-N 3.34Å; E296-V298 PolarHBondContact O-N 3.07Å; E296-V298 VanDerWaalsContact O-N 3.12Å; E296-Q299 WeakPolarHBondContact O-CB 3.36Å; E296-Q299 WeakPolarHBondContact O-CG 3.06Å; E296-Q299 PolarHBondContact O-N 3.45Å; E296-Q299 VanDerWaalsContact O-N 3.07Å
297	W	94.6	Very high	94.2	Very high	19 Å²	19	55.8 Å²	55.8	7%	0.072	28%	0.283	C	S	.	.	G	3₁₀ helix	trans	-65.4	-14.1	176.9	-67.7	-29.8	0	0	0	113.9	T253 A257 E258 I261 L290 L293 R294 P295 Q299 M300 F305	T253-W297 HydrophobicContact CG2-CH2 3.93Å; T253-W297 HydrophobicContact CG2-CZ2 4.3Å; A257-W297 HydrophobicContact CB-CH2 3.53Å; A257-W297 HydrophobicContact CB-CZ3 4.04Å; E258-W297 HydrophobicContact CG-CZ2 4.06Å; I261-W297 HydrophobicContact CD1-CD2 4.07Å; I261-W297 HydrophobicContact CD1-CE3 4.12Å; I261-W297 HydrophobicContact CD1-CG 4.4Å; I261-W297 HydrophobicContact CG1-CD2 4.11Å; I261-W297 HydrophobicContact CG1-CG 4.26Å; L290-W297 HydrophobicContact CB-CE3 4.11Å; L290-W297 HydrophobicContact CD2-CE3 3.93Å; L290-W297 HydrophobicContact CD2-CZ3 3.75Å; L293-W297 HydrophobicContact CB-CH2 4.32Å; L293-W297 HydrophobicContact CB-CZ3 3.78Å; L293-W297 HydrophobicContact CD1-CZ3 4.28Å; R294-W297 HydrophobicContact CB-CD2 3.82Å; R294-W297 HydrophobicContact CB-CE3 3.84Å; R294-W297 HydrophobicContact CB-CG 4.43Å; R294-W297 HydrophobicContact CB-CH2 4.1Å; R294-W297 HydrophobicContact CB-CZ2 4.09Å; R294-W297 HydrophobicContact CB-CZ3 3.99Å; R294-W297 HydrophobicContact CG-CD2 4.38Å; R294-W297 PolarHBondContact O-N 3.43Å; P295-W297 PolarHBondContact O-N 3.17Å; P295-W297 VanDerWaalsContact O-N 3.14Å; W297-Q299 PolarHBondContact O-N 3Å; W297-M300 WeakPolarHBondContact O-CB 3.42Å; W297-M300 PolarHBondContact O-N 3.3Å; W297-F305 HydrophobicContact CB-CZ 4.44Å
298	V	94.1	Very high	94.1	Very high	22 Å²	22	58.3 Å²	58.3	13%	0.133	29%	0.294	C	S	.	.	G	3₁₀ helix	trans	-50.9	-37.9	168	167.4	0	0	0	0	111.5	Y291 P295 E296 M300 A301 P302 F305 I312	Y291-V298 HydrophobicContact CD2-CG2 3.67Å; Y291-V298 HydrophobicContact CE2-CG2 3.92Å; P295-V298 VanDerWaalsContact O-CB 3.27Å; P295-V298 WeakPolarHBondContact O-CB 3.29Å; P295-V298 WeakPolarHBondContact O-CG2 3.29Å; P295-V298 PolarHBondContact O-N 3.08Å; P295-V298 VanDerWaalsContact O-N 3.1Å; E296-V298 PolarHBondContact O-N 3.07Å; E296-V298 VanDerWaalsContact O-N 3.12Å; V298-M300 PolarHBondContact O-N 3.39Å; V298-M300 VanDerWaalsContact O-N 3.12Å; V298-A301 CarbonylContact O-C 3.34Å; V298-A301 PolarHBondContact O-N 2.89Å; V298-A301 VanDerWaalsContact O-N 3.09Å; V298-P302 WeakPolarHBondContact O-CA 3.41Å; V298-P302 VanDerWaalsContact O-CD 3.24Å; V298-P302 WeakPolarHBondContact O-CD 3.48Å; V298-P302 WeakPolarHBondContact O-CG 3.31Å; V298-F305 HydrophobicContact CG2-CB 4.24Å; V298-F305 HydrophobicContact CG2-CD1 3.7Å; V298-F305 HydrophobicContact CG2-CE1 4.19Å; V298-F305 HydrophobicContact CG2-CG 3.94Å; V298-I312 HydrophobicContact CB-CG2 4.5Å; V298-I312 HydrophobicContact CG1-CG2 3.35Å; V298-I312 HydrophobicContact CG2-CD1 4.04Å; V298-I312 HydrophobicContact CG2-CG2 4.31Å
299	Q	92.5	Very high	93.9	Very high	162 Å²	162	54.3 Å²	54.3	76%	0.757	28%	0.277	S	S	*	.	G	3₁₀ helix	trans	-61	-24.3	-178.4	-63	-177.9	11	0	0	112.9	E296 W297	E296-Q299 WeakPolarHBondContact O-CB 3.36Å; E296-Q299 WeakPolarHBondContact O-CG 3.06Å; E296-Q299 PolarHBondContact O-N 3.45Å; E296-Q299 VanDerWaalsContact O-N 3.07Å; W297-Q299 PolarHBondContact O-N 3Å
300	M	92.5	Very high	93.6	Very high	75 Å²	75	58.6 Å²	58.6	37%	0.369	30%	0.304	S	S	.	.	G	3₁₀ helix	trans	-74.5	-32	178.6	-60	-176.2	69.4	0	0	112.6	I261 Y262 M265 W297 V298	I261-M300 HydrophobicContact CG1-SD 4.06Å; Y262-M300 HydrophobicContact CD1-CE 3.84Å; Y262-M300 HydrophobicContact CE1-CE 3.85Å; M265-M300 HydrophobicContact CB-CE 4.38Å; M265-M300 HydrophobicContact CE-CB 3.9Å; M265-M300 HydrophobicContact CE-CE 4.41Å; M265-M300 HydrophobicContact CE-CG 4.43Å; M265-M300 HydrophobicContact CE-SD 3.86Å; M265-M300 HydrophobicContact CG-CB 4.36Å; M265-M300 HydrophobicContact CG-CE 4.44Å; W297-M300 WeakPolarHBondContact O-CB 3.42Å; W297-M300 PolarHBondContact O-N 3.3Å; V298-M300 PolarHBondContact O-N 3.39Å; V298-M300 VanDerWaalsContact O-N 3.12Å
301	A	92.3	Very high	93	Very high	4 Å²	4	66.4 Å²	66.4	3%	0.033	35%	0.345	C	S	.	.			trans	-151	64.3	-177.8	0	0	0	0	0	113	M265 L269 V298 T303 L304 F305	M265-A301 HydrophobicContact CG-CB 4.34Å; M265-A301 HydrophobicContact SD-CB 3.94Å; L269-A301 HydrophobicContact CD2-CB 4.12Å; V298-A301 CarbonylContact O-C 3.34Å; V298-A301 PolarHBondContact O-N 2.89Å; V298-A301 VanDerWaalsContact O-N 3.09Å; A301-T303 VanDerWaalsContact C-N 3.26Å; A301-T303 PolarHBondContact O-N 3.4Å; A301-T303 VanDerWaalsContact O-N 3.13Å; A301-L304 HydrophobicContact CB-CB 3.89Å; A301-L304 HydrophobicContact CB-CD2 4.28Å; A301-L304 WeakPolarHBondContact O-CB 3.02Å; A301-L304 PolarHBondContact O-N 2.98Å; A301-F305 HydrophobicContact CB-CD2 4.38Å; A301-F305 WeakPolarHBondContact O-CD2 3.42Å; A301-F305 PolarHBondContact O-N 2.84Å
302	P	92.1	Very high	92.6	Very high	47 Å²	47	63.6 Å²	63.6	31%	0.305	34%	0.336	S	S	.	.	H	α-helix	trans	-58.5	-35.4	-171.9	-23.7	32.7	0	0	0	113.9	V298 L304 F305 S306 L313	V298-P302 WeakPolarHBondContact O-CA 3.41Å; V298-P302 VanDerWaalsContact O-CD 3.24Å; V298-P302 WeakPolarHBondContact O-CD 3.48Å; V298-P302 WeakPolarHBondContact O-CG 3.31Å; P302-L304 VanDerWaalsContact C-N 3.34Å; P302-L304 PolarHBondContact O-N 3.44Å; P302-F305 PolarHBondContact O-N 3.14Å; P302-S306 WeakPolarHBondContact O-CB 3.43Å; P302-S306 PolarHBondContact O-N 3.4Å; P302-S306 PolarHBondContact O-OG 2.9Å; P302-L313 HydrophobicContact CB-CD2 3.76Å
303	T	90.9	Very high	92	Very high	89 Å²	89	63.5 Å²	63.5	55%	0.546	33%	0.332	S	S	.	.	H	α-helix	trans	-70.6	-26.6	178.4	54.9	0	0	0	0	113.4	A301 S306 K307	A301-T303 VanDerWaalsContact C-N 3.26Å; A301-T303 PolarHBondContact O-N 3.4Å; A301-T303 VanDerWaalsContact O-N 3.13Å; T303-S306 WeakPolarHBondContact CA-OG 3.48Å; T303-S306 PolarHBondContact O-OG 3.41Å; T303-K307 WeakPolarHBondContact O-CG 3.32Å
304	L	92.8	Very high	91.1	Very high	0 Å²	0	68 Å²	68	0%	0	36%	0.362	C	S	.	.	H	α-helix	trans	-74.5	-49.2	173.4	174	63.4	0	0	0	110	M265 L268 L269 M283 V287 A301 P302 K307 F308	M265-L304 HydrophobicContact SD-CD2 4.43Å; L268-L304 HydrophobicContact CB-CD2 3.9Å; L268-L304 HydrophobicContact CD1-CD2 4.37Å; L269-L304 HydrophobicContact CD2-CB 4.28Å; L269-L304 HydrophobicContact CD2-CD2 4.39Å; M283-L304 HydrophobicContact CG-CD1 4.44Å; M283-L304 HydrophobicContact SD-CD1 4Å; V287-L304 HydrophobicContact CG2-CD1 4.35Å; V287-L304 HydrophobicContact CG2-CD2 4.36Å; V287-L304 HydrophobicContact CG2-CG 4.07Å; A301-L304 HydrophobicContact CB-CB 3.89Å; A301-L304 HydrophobicContact CB-CD2 4.28Å; A301-L304 WeakPolarHBondContact O-CB 3.02Å; A301-L304 PolarHBondContact O-N 2.98Å; P302-L304 VanDerWaalsContact C-N 3.34Å; P302-L304 PolarHBondContact O-N 3.44Å; L304-K307 PolarHBondContact O-N 3.17Å; L304-F308 HydrophobicContact CD1-CE2 4.21Å; L304-F308 WeakPolarHBondContact O-CD2 3.42Å
305	F	94.6	Very high	90.4	Very high	0 Å²	0	70.2 Å²	70.2	0%	0	39%	0.385	C	S	.	.	H	α-helix	trans	-64.3	-42.4	-176.4	-83	-99.5	0	0	0	112.6	M265 V287 L290 W297 V298 A301 P302 K307 F308 I309 I312	M265-F305 HydrophobicContact CE-CE2 4.18Å; M265-F305 HydrophobicContact SD-CE2 4.23Å; V287-F305 HydrophobicContact CG1-CB 4.31Å; V287-F305 HydrophobicContact CG1-CD1 3.62Å; V287-F305 HydrophobicContact CG1-CE1 4.07Å; V287-F305 HydrophobicContact CG1-CG 3.95Å; L290-F305 HydrophobicContact CB-CE1 4.22Å; L290-F305 HydrophobicContact CB-CZ 4.09Å; L290-F305 HydrophobicContact CD1-CZ 4.37Å; W297-F305 HydrophobicContact CB-CZ 4.44Å; V298-F305 HydrophobicContact CG2-CB 4.24Å; V298-F305 HydrophobicContact CG2-CD1 3.7Å; V298-F305 HydrophobicContact CG2-CE1 4.19Å; V298-F305 HydrophobicContact CG2-CG 3.94Å; A301-F305 HydrophobicContact CB-CD2 4.38Å; A301-F305 WeakPolarHBondContact O-CD2 3.42Å; A301-F305 PolarHBondContact O-N 2.84Å; P302-F305 PolarHBondContact O-N 3.14Å; F305-K307 PolarHBondContact O-N 3.32Å; F305-K307 VanDerWaalsContact O-N 3.13Å; F305-F308 PolarHBondContact O-N 2.91Å; F305-I309 HydrophobicContact CD1-CD1 4.19Å; F305-I309 PolarHBondContact O-N 3.3Å; F305-I312 HydrophobicContact CB-CD1 3.7Å; F305-I312 HydrophobicContact CB-CG2 4.33Å; F305-I312 HydrophobicContact CD1-CD1 4.38Å
306	S	93.3	Very high	89.8	Confident	38 Å²	38	70.3 Å²	70.3	27%	0.266	39%	0.392	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62.3	-18.4	179.4	51.5	0	0	0	0	115.3	P302 T303 F308	P302-S306 WeakPolarHBondContact O-CB 3.43Å; P302-S306 PolarHBondContact O-N 3.4Å; P302-S306 PolarHBondContact O-OG 2.9Å; T303-S306 WeakPolarHBondContact CA-OG 3.48Å; T303-S306 PolarHBondContact O-OG 3.41Å; S306-F308 VanDerWaalsContact C-N 3.28Å; S306-F308 PolarHBondContact O-N 2.85Å
307	K	91.5	Very high	89.4	Confident	130 Å²	130	67.6 Å²	67.6	57%	0.565	39%	0.385	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.1	-21.6	173.9	-69.5	177.8	-175.4	178.5	0	113.3	Q272 T303 L304 F305	Q272-K307 VanDerWaalsContact NE2-NZ 3.16Å; T303-K307 WeakPolarHBondContact O-CG 3.32Å; L304-K307 PolarHBondContact O-N 3.17Å; F305-K307 PolarHBondContact O-N 3.32Å; F305-K307 VanDerWaalsContact O-N 3.13Å
308	F	93	Very high	89	Confident	54 Å²	54	74.6 Å²	74.6	24%	0.237	42%	0.418	C	S	.	.	T	Hydrogen-bonded Turn	trans	-121.2	-15.4	-172.5	-60.4	-74.6	0	0	0	113.9	M283 A284 V287 K288 L304 F305 S306	M283-F308 HydrophobicContact CB-CE1 4.45Å; M283-F308 HydrophobicContact CB-CE2 4.31Å; M283-F308 HydrophobicContact CB-CZ 3.84Å; M283-F308 HydrophobicContact CG-CD2 4.39Å; M283-F308 HydrophobicContact CG-CE1 4.36Å; M283-F308 HydrophobicContact CG-CE2 3.4Å; M283-F308 HydrophobicContact CG-CZ 3.38Å; A284-F308 HydrophobicContact CB-CD1 3.51Å; A284-F308 HydrophobicContact CB-CE1 3.89Å; A284-F308 HydrophobicContact CB-CG 4.25Å; V287-F308 HydrophobicContact CB-CB 4.34Å; V287-F308 HydrophobicContact CB-CD2 4.11Å; V287-F308 HydrophobicContact CB-CG 4.46Å; V287-F308 HydrophobicContact CG1-CB 3.96Å; V287-F308 HydrophobicContact CG1-CD2 4.09Å; V287-F308 HydrophobicContact CG1-CG 4.42Å; V287-F308 HydrophobicContact CG2-CD2 3.92Å; V287-F308 HydrophobicContact CG2-CE2 4.34Å; K288-F308 WeakPolarHBondContact CE-O 3.38Å; L304-F308 HydrophobicContact CD1-CE2 4.21Å; L304-F308 WeakPolarHBondContact O-CD2 3.42Å; F305-F308 PolarHBondContact O-N 2.91Å; S306-F308 VanDerWaalsContact C-N 3.28Å; S306-F308 PolarHBondContact O-N 2.85Å
309	I	92.4	Very high	88.8	Confident	23 Å²	23	78 Å²	78	12%	0.118	44%	0.443	C	S	.	.	S	Bend	trans	-132.8	122.9	-179.1	-54	170.8	0	0	0	108	V287 K288 Y291 F305 I312	V287-I309 HydrophobicContact CG1-CD1 4.1Å; V287-I309 HydrophobicContact CG1-CG1 4.42Å; K288-I309 HydrophobicContact CG-CD1 4.48Å; K288-I309 HydrophobicContact CG-CG1 4.11Å; Y291-I309 VanDerWaalsContact CB-CD1 3.44Å; Y291-I309 HydrophobicContact CD1-CD1 4.03Å; Y291-I309 HydrophobicContact CD2-CD1 4.03Å; Y291-I309 HydrophobicContact CG-CD1 3.57Å; F305-I309 HydrophobicContact CD1-CD1 4.19Å; F305-I309 PolarHBondContact O-N 3.3Å; I309-I312 HydrophobicContact CB-CD1 3.4Å; I309-I312 VanDerWaalsContact CB-CD1 3.4Å; I309-I312 HydrophobicContact CB-CG1 3.93Å; I309-I312 HydrophobicContact CD1-CD1 3.82Å; I309-I312 HydrophobicContact CG1-CD1 4.16Å; I309-I312 HydrophobicContact CG2-CD1 3.58Å; I309-I312 HydrophobicContact CG2-CG1 3.73Å
310	P	89.4	Confident	88.5	Confident	101 Å²	101	73.8 Å²	73.8	66%	0.656	42%	0.423	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.7	159.6	179.6	30.2	-35	0	0	0	111.5	I312	P310-I312 PolarHBondContact O-N 2.91Å; P310-I312 VanDerWaalsContact O-N 3.12Å
311	N	86.2	Confident	88.3	Confident	163 Å²	163	75 Å²	75	87%	0.872	43%	0.43	S	S	*	.	T	Hydrogen-bonded Turn	trans	59.2	22.9	171.5	-52.9	-31.6	0	0	0	115.7
312	I	87	Confident	88.1	Confident	31 Å²	31	79.1 Å²	79.1	16%	0.159	46%	0.459	C	S	.	.			trans	-78.7	-37.4	174.4	-73.6	-164.2	0	0	0	112.4	Y291 V298 F305 I309 P310	Y291-I312 HydrophobicContact CD2-CD1 4.26Å; Y291-I312 HydrophobicContact CE2-CD1 4.23Å; V298-I312 HydrophobicContact CB-CG2 4.5Å; V298-I312 HydrophobicContact CG1-CG2 3.35Å; V298-I312 HydrophobicContact CG2-CD1 4.04Å; V298-I312 HydrophobicContact CG2-CG2 4.31Å; F305-I312 HydrophobicContact CB-CD1 3.7Å; F305-I312 HydrophobicContact CB-CG2 4.33Å; F305-I312 HydrophobicContact CD1-CD1 4.38Å; I309-I312 HydrophobicContact CB-CD1 3.4Å; I309-I312 VanDerWaalsContact CB-CD1 3.4Å; I309-I312 HydrophobicContact CB-CG1 3.93Å; I309-I312 HydrophobicContact CD1-CD1 3.82Å; I309-I312 HydrophobicContact CG1-CD1 4.16Å; I309-I312 HydrophobicContact CG2-CD1 3.58Å; I309-I312 HydrophobicContact CG2-CG1 3.73Å; P310-I312 PolarHBondContact O-N 2.91Å; P310-I312 VanDerWaalsContact O-N 3.12Å
313	L	81.7	Confident	88	Confident	85 Å²	85	82.7 Å²	82.7	45%	0.445	47%	0.472	S	S	.	.	S	Bend	trans	-85.8	150.6	176.5	-65.6	173.9	0	0	0	109.5	P302	P302-L313 HydrophobicContact CB-CD2 3.76Å
314	P	79.6	Confident	87.9	Confident	111 Å²	111	83.1 Å²	83.1	72%	0.721	46%	0.464	S	S	*	.	P	Polyproline II helix	trans	-51.3	141.8	171.8	-25.3	34.2	0	0	0	111	A316	P314-A316 PolarHBondContact O-N 2.75Å
315	P	79.6	Confident	87.8	Confident	113 Å²	113	85.4 Å²	85.4	73%	0.734	48%	0.483	S	S	*	.	P	Polyproline II helix	trans	-54.8	140.6	170.4	-23	33.1	0	0	0	110.3	V317	P315-V317 PolarHBondContact O-N 3.18Å
316	A	80.8	Confident	87.6	Confident	74 Å²	74	87.9 Å²	87.9	61%	0.612	50%	0.503	S	S	*	.	P	Polyproline II helix	trans	-60.5	128.8	174.6	0	0	0	0	0	109.8	P314 Y324	P314-A316 PolarHBondContact O-N 2.75Å; A316-Y324 HydrophobicContact CB-CE2 4.06Å
317	V	86.8	Confident	87.5	Confident	79 Å²	79	91.2 Å²	91.2	48%	0.479	52%	0.515	S	S	.	.	P	Polyproline II helix	trans	-97.2	144.8	179.2	-170.1	0	0	0	0	109.4	P315 S319 E320	P315-V317 PolarHBondContact O-N 3.18Å; V317-S319 WeakPolarHBondContact CG1-OG 3.4Å; V317-S319 PolarHBondContact O-N 3.27Å; V317-S319 VanDerWaalsContact O-N 3.16Å; V317-E320 HydrophobicContact CB-CG 4.45Å; V317-E320 WeakPolarHBondContact O-CB 3.48Å; V317-E320 PolarHBondContact O-N 3.45Å
318	E	86.2	Confident	87.4	Confident	165 Å²	165	89 Å²	89	77%	0.771	51%	0.509	S	S	*	.	G	3₁₀ helix	trans	-56.1	-34.6	-178.8	-168	177.7	-179	0	0	112.7	E320 L321	E318-E320 PolarHBondContact O-N 3.02Å; E318-L321 HydrophobicContact CB-CD1 4.41Å; E318-L321 HydrophobicContact CG-CD1 3.79Å; E318-L321 WeakPolarHBondContact O-CB 3.24Å; E318-L321 WeakPolarHBondContact O-CG 3.46Å; E318-L321 PolarHBondContact O-N 3.37Å
319	S	89	Confident	87.4	Confident	93 Å²	93	92.1 Å²	92.1	65%	0.65	52%	0.524	S	S	*	.	G	3₁₀ helix	trans	-61.6	-23.5	176.6	53.3	0	0	0	0	114.1	V317	V317-S319 WeakPolarHBondContact CG1-OG 3.4Å; V317-S319 PolarHBondContact O-N 3.27Å; V317-S319 VanDerWaalsContact O-N 3.16Å
320	E	86.9	Confident	87.5	Confident	74 Å²	74	96.6 Å²	96.6	35%	0.346	54%	0.543	S	S	.	.	G	3₁₀ helix	trans	-91.8	-7.7	-178.7	-61.2	179.4	166.9	0	0	112.5	V317 E318 S322 E323 Y324	V317-E320 HydrophobicContact CB-CG 4.45Å; V317-E320 WeakPolarHBondContact O-CB 3.48Å; V317-E320 PolarHBondContact O-N 3.45Å; E318-E320 PolarHBondContact O-N 3.02Å; E320-S322 VanDerWaalsContact C-N 3.3Å; E320-S322 PolarHBondContact O-N 2.94Å; E320-E323 WeakPolarHBondContact O-CA 3.35Å; E320-E323 WeakPolarHBondContact O-CB 3.48Å; E320-E323 PolarHBondContact O-N 3.14Å; E320-Y324 HydrophobicContact CB-CD2 4.07Å; E320-Y324 HydrophobicContact CB-CE2 3.49Å; E320-Y324 VanDerWaalsContact CB-CE2 3.49Å; E320-Y324 VanDerWaalsContact O-CD2 3.24Å; E320-Y324 WeakPolarHBondContact O-CD2 3.35Å; E320-Y324 PolarHBondContact O-N 3.11Å; E320-Y324 PolarHBondContact OE2-OH 3.08Å
321	L	87.9	Confident	87.5	Confident	100 Å²	100	97.1 Å²	97.1	52%	0.524	54%	0.535	S	S	.	.	H	α-helix	trans	-58	-39.4	-176.5	-72.9	175.6	0	0	0	113.3	E318 E323 Y324 A325	E318-L321 HydrophobicContact CB-CD1 4.41Å; E318-L321 HydrophobicContact CG-CD1 3.79Å; E318-L321 WeakPolarHBondContact O-CB 3.24Å; E318-L321 WeakPolarHBondContact O-CG 3.46Å; E318-L321 PolarHBondContact O-N 3.37Å; L321-E323 VanDerWaalsContact C-N 3.26Å; L321-E323 PolarHBondContact O-N 3.5Å; L321-Y324 PolarHBondContact O-N 3.09Å; L321-A325 WeakPolarHBondContact O-CB 3.48Å; L321-A325 PolarHBondContact O-N 3.15Å
322	S	89.4	Confident	87.7	Confident	91 Å²	91	93.5 Å²	93.5	64%	0.636	51%	0.513	S	S	*	.	H	α-helix	trans	-63.8	-34.3	176.1	48	0	0	0	0	112.3	E320 A326	E320-S322 VanDerWaalsContact C-N 3.3Å; E320-S322 PolarHBondContact O-N 2.94Å; S322-A326 WeakPolarHBondContact O-CB 3.27Å; S322-A326 PolarHBondContact O-N 3.36Å
323	E	89.3	Confident	87.9	Confident	122 Å²	122	99.8 Å²	99.8	57%	0.57	54%	0.535	S	S	*	.	H	α-helix	trans	-73.2	-43.6	178.2	-171.2	163.7	-172	0	0	110.9	E320 L321 A325 A326 Q327	E320-E323 WeakPolarHBondContact O-CA 3.35Å; E320-E323 WeakPolarHBondContact O-CB 3.48Å; E320-E323 PolarHBondContact O-N 3.14Å; L321-E323 VanDerWaalsContact C-N 3.26Å; L321-E323 PolarHBondContact O-N 3.5Å; E323-A325 VanDerWaalsContact C-N 3.33Å; E323-A325 PolarHBondContact O-N 2.93Å; E323-A326 PolarHBondContact O-N 3.03Å; E323-A326 VanDerWaalsContact O-N 3.16Å; E323-Q327 WeakPolarHBondContact O-CG 3.21Å; E323-Q327 PolarHBondContact O-N 3.28Å
324	Y	88.1	Confident	88.4	Confident	99 Å²	99	99.6 Å²	99.6	39%	0.388	53%	0.531	S	S	.	.	H	α-helix	trans	-58.7	-43.1	171.9	-64.6	-50.5	0	0	0	112.1	A316 E320 L321 A326 Q327 D328	A316-Y324 HydrophobicContact CB-CE2 4.06Å; E320-Y324 HydrophobicContact CB-CD2 4.07Å; E320-Y324 HydrophobicContact CB-CE2 3.49Å; E320-Y324 VanDerWaalsContact CB-CE2 3.49Å; E320-Y324 VanDerWaalsContact O-CD2 3.24Å; E320-Y324 WeakPolarHBondContact O-CD2 3.35Å; E320-Y324 PolarHBondContact O-N 3.11Å; E320-Y324 PolarHBondContact OE2-OH 3.08Å; L321-Y324 PolarHBondContact O-N 3.09Å; Y324-A326 VanDerWaalsContact C-N 3.33Å; Y324-A326 PolarHBondContact O-N 3.5Å; Y324-Q327 PolarHBondContact O-N 3.14Å; Y324-D328 PolarHBondContact O-N 3.02Å
325	A	90.2	Very high	88.9	Confident	48 Å²	48	97 Å²	97	40%	0.397	51%	0.511	S	S	.	.	H	α-helix	trans	-61.8	-39.8	175.9	0	0	0	0	0	112.2	L321 E323 D328 Q329	L321-A325 WeakPolarHBondContact O-CB 3.48Å; L321-A325 PolarHBondContact O-N 3.15Å; E323-A325 VanDerWaalsContact C-N 3.33Å; E323-A325 PolarHBondContact O-N 2.93Å; A325-D328 PolarHBondContact O-N 3.38Å; A325-Q329 WeakPolarHBondContact O-CB 3.48Å; A325-Q329 VanDerWaalsContact O-CG 3.31Å; A325-Q329 WeakPolarHBondContact O-CG 3.28Å; A325-Q329 PolarHBondContact O-N 3.39Å
326	A	92.4	Very high	89.3	Confident	51 Å²	51	96.2 Å²	96.2	42%	0.421	50%	0.5	S	S	.	.	H	α-helix	trans	-67.8	-40	176.6	0	0	0	0	0	112.3	S322 E323 Y324 Q329 K330	S322-A326 WeakPolarHBondContact O-CB 3.27Å; S322-A326 PolarHBondContact O-N 3.36Å; E323-A326 PolarHBondContact O-N 3.03Å; E323-A326 VanDerWaalsContact O-N 3.16Å; Y324-A326 VanDerWaalsContact C-N 3.33Å; Y324-A326 PolarHBondContact O-N 3.5Å; A326-Q329 PolarHBondContact O-N 3.47Å; A326-K330 WeakPolarHBondContact O-CB 3.28Å; A326-K330 PolarHBondContact O-N 3.3Å
327	Q	89.7	Confident	89.8	Confident	108 Å²	108	100.6 Å²	100.6	51%	0.505	51%	0.507	S	S	.	.	H	α-helix	trans	-61.7	-45.1	174	-71.3	177.6	9.8	0	0	111.3	E323 Y324 K330 F331	E323-Q327 WeakPolarHBondContact O-CG 3.21Å; E323-Q327 PolarHBondContact O-N 3.28Å; Y324-Q327 PolarHBondContact O-N 3.14Å; Q327-K330 WeakPolarHBondContact O-CB 3.43Å; Q327-K330 PolarHBondContact O-N 2.96Å; Q327-F331 PolarHBondContact O-N 2.99Å
328	D	90.9	Very high	89.9	Confident	83 Å²	83	102.4 Å²	102.4	44%	0.444	51%	0.514	S	S	.	.	H	α-helix	trans	-64.6	-43.5	177.9	-166.7	54.9	0	0	0	111.7	Y324 A325 K330 F331 Q332	Y324-D328 PolarHBondContact O-N 3.02Å; A325-D328 PolarHBondContact O-N 3.38Å; D328-K330 VanDerWaalsContact C-N 3.27Å; D328-K330 PolarHBondContact O-N 3.48Å; D328-F331 PolarHBondContact O-N 3.45Å; D328-Q332 WeakPolarHBondContact O-CB 3.31Å; D328-Q332 VanDerWaalsContact O-CG 3.3Å; D328-Q332 WeakPolarHBondContact O-CG 3.43Å; D328-Q332 PolarHBondContact O-N 3.46Å; D328-Q332 PolarHBondContact OD2-NE2 2.9Å
329	Q	92.3	Very high	89.9	Confident	120 Å²	120	97.2 Å²	97.2	56%	0.561	51%	0.506	S	S	*	.	H	α-helix	trans	-61	-34.1	173.4	-74.8	179.5	13.4	0	0	113.1	A325 A326 R333	A325-Q329 WeakPolarHBondContact O-CB 3.48Å; A325-Q329 VanDerWaalsContact O-CG 3.31Å; A325-Q329 WeakPolarHBondContact O-CG 3.28Å; A325-Q329 PolarHBondContact O-N 3.39Å; A326-Q329 PolarHBondContact O-N 3.47Å; Q329-R333 WeakPolarHBondContact O-CG 3.24Å; Q329-R333 PolarHBondContact O-N 3.49Å; Q329-R333 PolarHBondContact O-NE 3.26Å
330	K	93.7	Very high	89.7	Confident	118 Å²	118	99.6 Å²	99.6	51%	0.513	51%	0.505	S	S	.	.	H	α-helix	trans	-67.1	-48.9	174.2	-176.3	-173.9	172.4	-167.7	0	110.5	A326 Q327 D328 Q332 R333 E334	A326-K330 WeakPolarHBondContact O-CB 3.28Å; A326-K330 PolarHBondContact O-N 3.3Å; Q327-K330 WeakPolarHBondContact O-CB 3.43Å; Q327-K330 PolarHBondContact O-N 2.96Å; D328-K330 VanDerWaalsContact C-N 3.27Å; D328-K330 PolarHBondContact O-N 3.48Å; K330-Q332 PolarHBondContact O-N 3.21Å; K330-R333 WeakPolarHBondContact O-CB 3.42Å; K330-R333 PolarHBondContact O-N 3.44Å; K330-R333 VanDerWaalsContact O-N 3.14Å; K330-E334 WeakPolarHBondContact CE-OE1 3.34Å; K330-E334 PolarHBondContact O-N 2.88Å
331	F	90.1	Very high	89.4	Confident	112 Å²	112	100.9 Å²	100.9	49%	0.491	52%	0.518	S	S	.	.	H	α-helix	trans	-60.6	-43.9	178.8	-178.4	-114.8	0	0	0	112.3	Q327 D328 R333 E334 L335	Q327-F331 PolarHBondContact O-N 2.99Å; D328-F331 PolarHBondContact O-N 3.45Å; F331-R333 VanDerWaalsContact C-N 3.29Å; F331-R333 PolarHBondContact O-N 3.01Å; F331-E334 PolarHBondContact O-N 2.9Å; F331-L335 HydrophobicContact CD1-CD1 3.94Å; F331-L335 HydrophobicContact CD1-CG 4.48Å; F331-L335 HydrophobicContact CE1-CD1 3.47Å; F331-L335 VanDerWaalsContact CE1-CD1 3.47Å; F331-L335 HydrophobicContact CE1-CG 4.11Å; F331-L335 HydrophobicContact CE2-CD2 4.43Å; F331-L335 HydrophobicContact CE2-CG 4.29Å; F331-L335 HydrophobicContact CZ-CD1 3.8Å; F331-L335 HydrophobicContact CZ-CD2 4.12Å; F331-L335 HydrophobicContact CZ-CG 4.01Å; F331-L335 WeakPolarHBondContact O-CG 3.33Å; F331-L335 PolarHBondContact O-N 3.2Å
332	Q	89.7	Confident	88.6	Confident	86 Å²	86	105.4 Å²	105.4	40%	0.402	53%	0.528	S	S	.	.	H	α-helix	trans	-58.4	-39.8	174.9	-71.4	-179.3	26.7	0	0	112.3	D328 K330 L335 I336	D328-Q332 WeakPolarHBondContact O-CB 3.31Å; D328-Q332 VanDerWaalsContact O-CG 3.3Å; D328-Q332 WeakPolarHBondContact O-CG 3.43Å; D328-Q332 PolarHBondContact O-N 3.46Å; D328-Q332 PolarHBondContact OD2-NE2 2.9Å; K330-Q332 PolarHBondContact O-N 3.21Å; Q332-L335 PolarHBondContact O-N 2.66Å; Q332-I336 WeakPolarHBondContact O-CD1 3.38Å; Q332-I336 VanDerWaalsContact O-CG1 3.28Å; Q332-I336 WeakPolarHBondContact O-CG1 3.31Å; Q332-I336 PolarHBondContact O-N 2.9Å; Q332-I336 VanDerWaalsContact O-N 3.1Å
333	R	90.9	Very high	87.6	Confident	164 Å²	164	103.4 Å²	103.4	62%	0.619	52%	0.522	S	S	*	.	H	α-helix	trans	-66.4	-42.5	175.8	-76.6	-178.5	-69.9	156.2	-4.9	112.3	Q329 K330 F331 L335 I336 Q337	Q329-R333 WeakPolarHBondContact O-CG 3.24Å; Q329-R333 PolarHBondContact O-N 3.49Å; Q329-R333 PolarHBondContact O-NE 3.26Å; K330-R333 WeakPolarHBondContact O-CB 3.42Å; K330-R333 PolarHBondContact O-N 3.44Å; K330-R333 VanDerWaalsContact O-N 3.14Å; F331-R333 VanDerWaalsContact C-N 3.29Å; F331-R333 PolarHBondContact O-N 3.01Å; R333-L335 VanDerWaalsContact C-N 3.34Å; R333-I336 PolarHBondContact O-N 3.19Å; R333-Q337 PolarHBondContact O-N 2.79Å
334	E	92.9	Very high	86.2	Confident	81 Å²	81	104.3 Å²	104.3	38%	0.379	53%	0.531	S	S	.	.	H	α-helix	trans	-62.2	-41.2	176.4	-72.6	174.9	-175.2	0	0	111.6	K330 F331 Q337 N338	K330-E334 WeakPolarHBondContact CE-OE1 3.34Å; K330-E334 PolarHBondContact O-N 2.88Å; F331-E334 PolarHBondContact O-N 2.9Å; E334-Q337 PolarHBondContact O-N 3.47Å; E334-N338 WeakPolarHBondContact O-CB 3.27Å; E334-N338 PolarHBondContact O-N 2.82Å; E334-N338 PolarHBondContact O-ND2 3.17Å
335	L	89.5	Confident	85.2	Confident	56 Å²	56	103 Å²	103	29%	0.293	53%	0.528	S	S	.	.	H	α-helix	trans	-60.7	-45.9	174.3	-75.6	178.2	0	0	0	112.3	F331 Q332 R333 Q337 N338 G339 F340	F331-L335 HydrophobicContact CD1-CD1 3.94Å; F331-L335 HydrophobicContact CD1-CG 4.48Å; F331-L335 HydrophobicContact CE1-CD1 3.47Å; F331-L335 VanDerWaalsContact CE1-CD1 3.47Å; F331-L335 HydrophobicContact CE1-CG 4.11Å; F331-L335 HydrophobicContact CE2-CD2 4.43Å; F331-L335 HydrophobicContact CE2-CG 4.29Å; F331-L335 HydrophobicContact CZ-CD1 3.8Å; F331-L335 HydrophobicContact CZ-CD2 4.12Å; F331-L335 HydrophobicContact CZ-CG 4.01Å; F331-L335 WeakPolarHBondContact O-CG 3.33Å; F331-L335 PolarHBondContact O-N 3.2Å; Q332-L335 PolarHBondContact O-N 2.66Å; R333-L335 VanDerWaalsContact C-N 3.34Å; L335-Q337 VanDerWaalsContact C-N 3.29Å; L335-Q337 PolarHBondContact O-N 3.45Å; L335-N338 CarbonylContact O-C 3.48Å; L335-N338 PolarHBondContact O-N 3.12Å; L335-N338 VanDerWaalsContact O-N 3.14Å; L335-G339 PolarHBondContact O-N 3.27Å; L335-F340 HydrophobicContact CB-CB 4.14Å; L335-F340 HydrophobicContact CD2-CD2 4.04Å; L335-F340 HydrophobicContact CD2-CG 4.39Å; L335-F340 WeakPolarHBondContact O-CA 3.42Å; L335-F340 WeakPolarHBondContact O-CB 3.3Å; L335-F340 PolarHBondContact O-N 3.3Å
336	I	89.8	Confident	83.8	Confident	97 Å²	97	105.5 Å²	105.5	50%	0.497	54%	0.542	S	S	.	.	H	α-helix	trans	-59.8	-42.9	176.4	-68.7	163.7	0	0	0	110.4	Q332 R333 N338 G339 T341	Q332-I336 WeakPolarHBondContact O-CD1 3.38Å; Q332-I336 VanDerWaalsContact O-CG1 3.28Å; Q332-I336 WeakPolarHBondContact O-CG1 3.31Å; Q332-I336 PolarHBondContact O-N 2.9Å; Q332-I336 VanDerWaalsContact O-N 3.1Å; R333-I336 PolarHBondContact O-N 3.19Å; I336-N338 VanDerWaalsContact C-N 3.28Å; I336-N338 PolarHBondContact O-N 3.13Å; I336-G339 PolarHBondContact O-N 2.89Å; I336-T341 HydrophobicContact CG2-CG2 4.5Å
337	Q	89.6	Confident	82.3	Confident	165 Å²	165	114.6 Å²	114.6	77%	0.771	57%	0.566	S	S	*	*	H	α-helix	trans	-63.7	-34.3	177.6	-168.4	173.4	19.8	0	0	112.3	R333 E334 L335 G339	R333-Q337 PolarHBondContact O-N 2.79Å; E334-Q337 PolarHBondContact O-N 3.47Å; L335-Q337 VanDerWaalsContact C-N 3.29Å; L335-Q337 PolarHBondContact O-N 3.45Å; Q337-G339 PolarHBondContact O-N 3.13Å
338	N	89.4	Confident	80.8	Confident	117 Å²	117	115.8 Å²	115.8	63%	0.626	57%	0.569	S	S	*	*	T	Hydrogen-bonded Turn	trans	-80.4	11.3	174.6	-68.4	-29.3	0	0	0	113.6	E334 L335 I336 F340	E334-N338 WeakPolarHBondContact O-CB 3.27Å; E334-N338 PolarHBondContact O-N 2.82Å; E334-N338 PolarHBondContact O-ND2 3.17Å; L335-N338 CarbonylContact O-C 3.48Å; L335-N338 PolarHBondContact O-N 3.12Å; L335-N338 VanDerWaalsContact O-N 3.14Å; I336-N338 VanDerWaalsContact C-N 3.28Å; I336-N338 PolarHBondContact O-N 3.13Å; N338-F340 HydrophobicContact CB-CD2 4.05Å; N338-F340 HydrophobicContact CB-CE2 4.28Å
339	G	87.1	Confident	79.3	Confident	57 Å²	57	123.5 Å²	123.5	59%	0.588	59%	0.592	S	S	*	*	T	Hydrogen-bonded Turn	trans	88.2	1.1	174.9	0	0	0	0	0	115.1	L335 I336 Q337 T341	L335-G339 PolarHBondContact O-N 3.27Å; I336-G339 PolarHBondContact O-N 2.89Å; Q337-G339 PolarHBondContact O-N 3.13Å; G339-T341 PolarHBondContact O-N 3.23Å
340	F	83.9	Confident	77.5	Confident	143 Å²	143	122.4 Å²	122.4	63%	0.627	60%	0.604	S	S	*	*			trans	-82.2	66.2	174.1	-61.9	-86.7	0	0	0	110.6	L335 N338	L335-F340 HydrophobicContact CB-CB 4.14Å; L335-F340 HydrophobicContact CD2-CD2 4.04Å; L335-F340 HydrophobicContact CD2-CG 4.39Å; L335-F340 WeakPolarHBondContact O-CA 3.42Å; L335-F340 WeakPolarHBondContact O-CB 3.3Å; L335-F340 PolarHBondContact O-N 3.3Å; N338-F340 HydrophobicContact CB-CD2 4.05Å; N338-F340 HydrophobicContact CB-CE2 4.28Å
341	T	80.5	Confident	75.2	Confident	101 Å²	101	119.8 Å²	119.8	62%	0.62	61%	0.611	S	S	*	*			trans	-70.2	146.7	175	56.3	0	0	0	0	110.8	I336 G339 G343	I336-T341 HydrophobicContact CG2-CG2 4.5Å; G339-T341 PolarHBondContact O-N 3.23Å; T341-G343 PolarHBondContact O-N 2.95Å
342	R	71.3	Confident	73.1	Confident	194 Å²	194	122.1 Å²	122.1	73%	0.732	63%	0.628	S	S	*	*			trans	-62.5	100	166.8	-93.5	-177.1	173.5	-155.8	5	107.6	Q345	R342-Q345 VanDerWaalsContact CD-NE2 3.33Å
343	G	69.1	Low	70.9	Confident	50 Å²	50	126.9 Å²	126.9	52%	0.515	65%	0.65	S	S	.	*			trans	-57.7	166.4	169.2	0	0	0	0	0	111.8	T341 Q345	T341-G343 PolarHBondContact O-N 2.95Å; G343-Q345 WeakPolarHBondContact O-CG 3.34Å; G343-Q345 PolarHBondContact O-N 3.11Å
344	D	60.1	Low	68.7	Low	141 Å²	141	127 Å²	127	75%	0.754	66%	0.663	S	S	*	*			trans	-48.5	113	-178.1	-175.2	6.8	0	0	0	112	S346	D344-S346 VanDerWaalsContact C-N 3.26Å; D344-S346 PolarHBondContact O-N 3.09Å; D344-S346 WeakPolarHBondContact OD1-CB 3.42Å; D344-S346 PolarHBondContact OD1-N 3.47Å
345	Q	65.4	Low	66.2	Low	71 Å²	71	127.8 Å²	127.8	33%	0.332	68%	0.682	S	S	.	*	G	3₁₀ helix	trans	-85.6	4.4	-179.8	-60.2	-147.8	11.3	0	0	113.2	R342 G343 R347 K348	R342-Q345 VanDerWaalsContact CD-NE2 3.33Å; G343-Q345 WeakPolarHBondContact O-CG 3.34Å; G343-Q345 PolarHBondContact O-N 3.11Å; Q345-R347 PolarHBondContact O-N 3.07Å; Q345-K348 HydrophobicContact CB-CD 4.39Å; Q345-K348 PolarHBondContact O-N 2.66Å; Q345-K348 VanDerWaalsContact OE1-CD 3.24Å
346	S	60.8	Low	63.7	Low	100 Å²	100	135.3 Å²	135.3	70%	0.699	71%	0.708	S	S	*	*	G	3₁₀ helix	trans	-54.1	-22.7	174.9	-179.1	0	0	0	0	113.6	D344	D344-S346 VanDerWaalsContact C-N 3.26Å; D344-S346 PolarHBondContact O-N 3.09Å; D344-S346 WeakPolarHBondContact OD1-CB 3.42Å; D344-S346 PolarHBondContact OD1-N 3.47Å
347	R	60.6	Low	61.1	Low	242 Å²	242	137.9 Å²	137.9	91%	0.913	72%	0.723	S	S	*	*	G	3₁₀ helix	trans	-92.3	-1.8	177.7	-79.4	-179.1	158	-169.3	-4.8	115.9	Q345 R349	Q345-R347 PolarHBondContact O-N 3.07Å; R347-R349 PolarHBondContact O-N 2.87Å
348	K	58.8	Low	58.4	Low	134 Å²	134	134.8 Å²	134.8	58%	0.583	72%	0.72	S	S	*	*	S	Bend	trans	-70.5	130.9	172.5	-73.8	-170	177.4	177.9	0	108.6	Q345 A350	Q345-K348 HydrophobicContact CB-CD 4.39Å; Q345-K348 PolarHBondContact O-N 2.66Å; Q345-K348 VanDerWaalsContact OE1-CD 3.24Å; K348-A350 PolarHBondContact O-N 3.44Å
349	R	59	Low	55.9	Low	244 Å²	244	135.1 Å²	135.1	92%	0.921	73%	0.731	S	S	*	*			trans	-53.5	113.9	171.6	-70.9	-179.1	-172.9	157.1	2	107.5	R347 G351	R347-R349 PolarHBondContact O-N 2.87Å; R349-G351 PolarHBondContact O-N 3.25Å; R349-G351 VanDerWaalsContact O-N 3.08Å
350	A	55.9	Low	53.4	Low	97 Å²	97	138 Å²	138	80%	0.802	74%	0.742	S	S	*	*			trans	-55.4	115.2	160.6	0	0	0	0	0	105.6	K348 D352	K348-A350 PolarHBondContact O-N 3.44Å; A350-D352 PolarHBondContact O-N 3.46Å
351	G	44	Very low	51.2	Low	64 Å²	64	135.6 Å²	135.6	66%	0.66	75%	0.749	S	S	*	*			trans	-57	136.8	168.8	0	0	0	0	0	107.6	R349 E353	R349-G351 PolarHBondContact O-N 3.25Å; R349-G351 VanDerWaalsContact O-N 3.08Å; G351-E353 PolarHBondContact O-N 2.86Å
352	D	45.8	Very low	48.9	Very low	161 Å²	161	137 Å²	137	86%	0.861	76%	0.762	S	S	*	*			trans	-46.4	102.7	177.5	-87.6	-40.7	0	0	0	110.2	A350 L354	A350-D352 PolarHBondContact O-N 3.46Å; D352-L354 VanDerWaalsContact C-N 3.28Å; D352-L354 PolarHBondContact O-N 2.71Å
353	E	45.4	Very low	47.1	Very low	186 Å²	186	132.4 Å²	132.4	87%	0.869	77%	0.765	S	S	*	*			trans	-65.1	99.9	156	-78.1	-167.1	154.3	0	0	105.8	G351 A355	G351-E353 PolarHBondContact O-N 2.86Å; E353-A355 PolarHBondContact O-N 3.28Å
354	L	43.3	Very low	45.5	Very low	167 Å²	167	136 Å²	136	87%	0.874	78%	0.782	S	S	*	*			trans	-47.8	105	169.8	-85.6	158.1	0	0	0	109.1	D352 Y356	D352-L354 VanDerWaalsContact C-N 3.28Å; D352-L354 PolarHBondContact O-N 2.71Å; L354-Y356 VanDerWaalsContact C-N 3.34Å; L354-Y356 PolarHBondContact O-N 3.45Å
355	A	40.2	Very low	44.3	Very low	96 Å²	96	134 Å²	134	79%	0.793	78%	0.779	S	S	*	*			trans	-60.5	92.9	172.8	0	0	0	0	0	109.8	E353 N357	E353-A355 PolarHBondContact O-N 3.28Å; A355-N357 PolarHBondContact O-N 3Å
356	Y	36.9	Very low	43.1	Very low	214 Å²	214	141.3 Å²	141.3	84%	0.839	80%	0.804	S	S	*	*			trans	-87	65.3	164.2	-141.3	-87.4	0	0	0	109.3	L354 S358	L354-Y356 VanDerWaalsContact C-N 3.34Å; L354-Y356 PolarHBondContact O-N 3.45Å; Y356-S358 PolarHBondContact O-N 3.19Å
357	N	35.4	Very low	41.8	Very low	152 Å²	152	140.4 Å²	140.4	81%	0.813	81%	0.81	S	S	*	*			trans	-90.1	89.8	168.2	-108.9	3.6	0	0	0	109.2	A355 S359	A355-N357 PolarHBondContact O-N 3Å; N357-S359 PolarHBondContact O-N 3.05Å
358	S	32.5	Very low	40.6	Very low	100 Å²	100	138.9 Å²	138.9	70%	0.699	81%	0.806	S	S	*	*			trans	-62.5	112	160.3	-88	0	0	0	0	109	Y356 S360	Y356-S358 PolarHBondContact O-N 3.19Å; S358-S360 PolarHBondContact O-N 3.24Å
359	S	37.5	Very low	39.5	Very low	124 Å²	124	147.6 Å²	147.6	87%	0.867	84%	0.835	S	S	*	*			trans	-71.9	117.1	168.2	-65.2	0	0	0	0	109.1	N357	N357-S359 PolarHBondContact O-N 3.05Å
360	S	34.8	Very low	38.6	Very low	116 Å²	116	142.8 Å²	142.8	81%	0.811	83%	0.831	S	S	*	*			trans	-122.5	117.3	157	-173.6	0	0	0	0	108.6	S358	S358-S360 PolarHBondContact O-N 3.24Å
361	A	37.3	Very low	37.6	Very low	94 Å²	94	145.2 Å²	145.2	78%	0.777	83%	0.833	S	S	*	*			trans	-69.8	139.4	-177.7	0	0	0	0	0	112.3
362	C	32.5	Very low	37.3	Very low	131 Å²	131	149.7 Å²	149.7	89%	0.885	84%	0.842	S	S	*	*			trans	-145.3	131.1	149	-53.1	0	0	0	0	110
363	A	34	Very low	36.8	Very low	97 Å²	97	149 Å²	149	80%	0.802	84%	0.841	S	S	*	*			trans	-90.7	156.8	-174.5	0	0	0	0	0	114.3
364	S	35.3	Very low	36.2	Very low	125 Å²	125	146.7 Å²	146.7	87%	0.874	84%	0.839	S	S	*	*			trans	140.1	142.8	150.6	-76.2	0	0	0	0	110.2
365	S	35.5	Very low	35.8	Very low	99 Å²	99	145.3 Å²	145.3	69%	0.692	84%	0.837	S	S	*	*			cis	-170.4	143.2	-5.5	-171.7	0	0	0	0	107.2
366	R	40.3	Very low	35.5	Very low	224 Å²	224	148.9 Å²	148.9	85%	0.845	84%	0.84	S	S	*	*			trans	35.4	130.5	151.5	-73.1	178.2	169.4	-174.8	-3	122.4
367	G	32.7	Very low	35.3	Very low	81 Å²	81	143.8 Å²	143.8	84%	0.835	84%	0.84	S	S	*	*			trans	-164.3	106.6	147.3	0	0	0	0	0	111.7
368	Y	36.2	Very low	35.3	Very low	211 Å²	211	143.2 Å²	143.2	83%	0.827	84%	0.842	S	S	*	*			trans	-64.1	143.2	178.3	-91	-99.4	0	0	0	113.6
369	R	35.6	Very low	35.6	Very low	316 Å²	316	147.1 Å²	147.1	100%	1.192	86%	0.855	S	S	*	*				-156.2	0	110.1	-112.4	-167.4	-171.2	-144.7	2.8	111.3

Retrieved 369 of 369 residues in 91.8 ms (Link to these results)

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