A0A096NUI3_PAPAN Loading...

Malic enzyme

AlphaFold DB (A0A2K5YM48), UniProt , Accession A0A096NUI3, Species PAPAN (Papio anubis, Olive baboon), Gene ME1, Length 572 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M33.8Very low64.2Low239 Ų239128.9 Ų128.9100%1.17763%0.63SS**  01210-79.1179.4-122.400106
2E25.9Very low66.9Low182 Ų182132.5 Ų132.585%0.8564%0.643SS**PPolyproline II helixtrans-55.8138.5168.5-71.8178.2160.400108.3E4E2-E4 PolarHBondContact O-N 3.45Å; E2-E4 VanDerWaalsContact O-N 3.13Å
3P39.8Very low69.2Low122 Ų122127 Ų12779%0.79262%0.616SS**PPolyproline II helixtrans-60.3120175.323.3-29.7000108.4V5P3-V5 PolarHBondContact O-N 3.05Å
4E54.1Low71.3Confident180 Ų180124 Ų12484%0.84160%0.595SS**PPolyproline II helixtrans-55.2126.8174.3-79.4-173.7154.100109E2E2-E4 PolarHBondContact O-N 3.45Å; E2-E4 VanDerWaalsContact O-N 3.13Å
5V57.9Low73.1Confident117 Ų117116.7 Ų116.771%0.70957%0.565SS**PPolyproline II helixtrans-59.3126.9177.1179.40000108.3P3 R7P3-V5 PolarHBondContact O-N 3.05Å; V5-R7 PolarHBondContact O-N 2.89Å
6P63.2Low74.7Confident68 Ų68117.9 Ų117.944%0.44256%0.563SS.*PPolyproline II helixtrans-55137.3-180-24.832.3000111.2R8 Q551P6-R8 PolarHBondContact O-N 3.31Å; P6-Q551 HydrophobicContact CB-CB 4.46Å
7R77.1Confident76.1Confident116 Ų116117.6 Ų117.644%0.43856%0.564SS.*PPolyproline II helixtrans-56.4138.1172.1-71.1-176.5-177.6-175.92.4108.8V5 M544 D550 Q551V5-R7 PolarHBondContact O-N 2.89Å; R7-M544 PolarHBondContact NH1-O 2.77Å; R7-M544 PolarHBondContact NH2-O 3.23Å; R7-M544 VanDerWaalsContact NH2-O 3.13Å; R7-D550 WeakPolarHBondContact CB-OD1 3.38Å; R7-D550 CarbonylContact O-C 3.53Å; R7-D550 WeakPolarHBondContact O-CA 3.2Å; R7-D550 WeakPolarHBondContact O-CB 3.35Å; R7-Q551 PolarHBondContact O-N 3.11Å
8R77.9Confident77.3Confident151 Ų151111.1 Ų111.157%0.5753%0.533SS*.BIsolated β-bridgetrans-99.7134.8-176.8-65.1175.7173.9-165.6-15.6110.1P6 D555P6-R8 PolarHBondContact O-N 3.31Å; R8-D555 IonicContact CZ-OD1 3.89Å; R8-D555 VanDerWaalsContact CZ-OD1 3.25Å; R8-D555 IonicContact CZ-OD2 2.85Å; R8-D555 IonicContact NH1-OD1 3.47Å; R8-D555 PolarHBondContact NH1-OD1 3.5Å; R8-D555 VanDerWaalsContact NH1-OD1 3.14Å; R8-D555 IonicContact NH1-OD2 2.78Å; R8-D555 PolarHBondContact NH1-OD2 2.89Å; R8-D555 IonicContact NH2-OD1 2.85Å; R8-D555 PolarHBondContact NH2-OD1 3.37Å; R8-D555 IonicContact NH2-OD2 3.97Å
9R90.6Very high78.4Confident65 Ų65106.6 Ų106.625%0.24551%0.513CS..  trans-130.6132.7172.3-179.1179.9-178.2174.47.7107.7H23 Q186 D550 Q551 I552R9-H23 PolarHBondContact NH1-O 3.44Å; R9-H23 VanDerWaalsContact NH1-O 3.16Å; R9-Q186 VanDerWaalsContact CZ-OE1 3.24Å; R9-Q186 VanDerWaalsContact NH1-NE2 3.1Å; R9-D550 HydrophobicContact CB-CB 4.19Å; R9-Q551 PolarHBondContact N-O 3.17Å; R9-I552 HydrophobicContact CB-CG2 4.35Å; R9-I552 VanDerWaalsContact O-CA 3.29Å; R9-I552 WeakPolarHBondContact O-CA 3.24Å
10H90.4Very high79.4Confident154 Ų154108.6 Ų108.671%0.71352%0.515SS*.  trans-93.7149.5172.172-82.7000109.9
11T95.3Very high80.3Confident24 Ų24104.8 Ų104.815%0.14750%0.498CS..  trans-149.5145.2172.9-178.10000110.6Q13 R14 L24 I552T11-Q13 PolarHBondContact OG1-N 3.18Å; T11-Q13 VanDerWaalsContact OG1-N 3.12Å; T11-R14 PolarHBondContact O-NH1 3.12Å; T11-R14 PolarHBondContact O-NH2 3.16Å; T11-L24 HydrophobicContact CG2-CD1 4.27Å; T11-L24 HydrophobicContact CG2-CD2 4.34Å; T11-I552 HydrophobicContact CG2-CB 4.21Å
12H96.4Very high83.3Confident172 Ų17294.4 Ų94.480%0.79645%0.449SS*.  trans-92.8-12.6170.5-61-63.9000112.7
13Q97.4Very high86.7Confident61 Ų6187.4 Ų87.429%0.28542%0.416SS..  trans-68.9139.5179.8-163.6169.80.100110.4T11 L17 L18 N21 L24T11-Q13 PolarHBondContact OG1-N 3.18Å; T11-Q13 VanDerWaalsContact OG1-N 3.12Å; Q13-L17 HydrophobicContact CG-CB 4.39Å; Q13-L17 VanDerWaalsContact NE2-C 3.27Å; Q13-L17 PolarHBondContact NE2-O 3.13Å; Q13-L18 HydrophobicContact CG-CB 4.3Å; Q13-L18 WeakPolarHBondContact O-CD1 3.49Å; Q13-N21 PolarHBondContact OE1-ND2 3.13Å; Q13-L24 HydrophobicContact CB-CD1 4.11Å
14R97.8Very high89.5Confident85 Ų8581.9 Ų81.932%0.32138%0.38SS..  trans-143.8171.2-176.7-66.9-67-178.7-75.7-1.8111T11T11-R14 PolarHBondContact O-NH1 3.12Å; T11-R14 PolarHBondContact O-NH2 3.16Å
15G98.3Very high91.6Very high14 Ų1473.6 Ų73.614%0.14434%0.341CS..Hα-helixtrans62.2-151.5171.500000113.5L17 L18 L38 N39 I40G15-L17 VanDerWaalsContact C-N 3.27Å; G15-L17 PolarHBondContact O-N 3.43Å; G15-L18 WeakPolarHBondContact O-CB 3.37Å; G15-L18 PolarHBondContact O-N 2.81Å; G15-L38 PolarHBondContact N-O 2.87Å; G15-N39 WeakPolarHBondContact CA-O 3.48Å; G15-I40 VanDerWaalsContact O-CG2 3.22Å; G15-I40 WeakPolarHBondContact O-CG2 3.4Å
16Y98.6Very high93.6Very high136 Ų13668.6 Ų68.653%0.53331%0.31SS..Hα-helixtrans-54.4-40.7-177.2175.8-101.8000113.1L18 T19 R20Y16-L18 PolarHBondContact O-N 3.41Å; Y16-T19 PolarHBondContact O-N 2.93Å; Y16-T19 PolarHBondContact O-OG1 3.28Å; Y16-R20 HydrophobicContact CD1-CG 4.1Å; Y16-R20 HydrophobicContact CE1-CG 3.64Å; Y16-R20 HydrophobicContact CE2-CG 4.46Å; Y16-R20 PolarHBondContact O-N 3.4Å
17L98.3Very high95.3Very high113 Ų11366.8 Ų66.859%0.59230%0.296SS*.Hα-helixtrans-61.6-31.6-178.7-66.4177.7000112.3Q13 G15 T19 R20 N21Q13-L17 HydrophobicContact CG-CB 4.39Å; Q13-L17 VanDerWaalsContact NE2-C 3.27Å; Q13-L17 PolarHBondContact NE2-O 3.13Å; G15-L17 VanDerWaalsContact C-N 3.27Å; G15-L17 PolarHBondContact O-N 3.43Å; L17-T19 VanDerWaalsContact C-N 3.31Å; L17-T19 PolarHBondContact O-N 3.17Å; L17-R20 WeakPolarHBondContact O-CB 3.15Å; L17-R20 PolarHBondContact O-N 3.47Å; L17-R20 VanDerWaalsContact O-N 3.12Å; L17-N21 PolarHBondContact O-N 3.25Å
18L98.4Very high96.3Very high0 Ų061.8 Ų61.80%028%0.279CS..Hα-helixtrans-62.8-37.4175.8-178151.2000111.8Q13 G15 Y16 R20 N21 L24 F30 L38 I40 I552Q13-L18 HydrophobicContact CG-CB 4.3Å; Q13-L18 WeakPolarHBondContact O-CD1 3.49Å; G15-L18 WeakPolarHBondContact O-CB 3.37Å; G15-L18 PolarHBondContact O-N 2.81Å; Y16-L18 PolarHBondContact O-N 3.41Å; L18-R20 PolarHBondContact O-N 3.22Å; L18-N21 PolarHBondContact O-N 3.37Å; L18-L24 HydrophobicContact CG-CB 4.24Å; L18-L24 HydrophobicContact CG-CD1 4.49Å; L18-F30 HydrophobicContact CD2-CE1 4.25Å; L18-F30 HydrophobicContact CD2-CE2 4.02Å; L18-F30 HydrophobicContact CD2-CZ 3.47Å; L18-F30 VanDerWaalsContact CD2-CZ 3.47Å; L18-L38 HydrophobicContact CD1-CB 4.34Å; L18-L38 HydrophobicContact CD1-CD1 4.11Å; L18-L38 HydrophobicContact CD1-CD2 3.93Å; L18-L38 HydrophobicContact CD1-CG 4.35Å; L18-L38 HydrophobicContact CD2-CD1 4.46Å; L18-I40 HydrophobicContact CD2-CD1 4.48Å; L18-I552 HydrophobicContact CD1-CD1 4.12Å
19T98.2Very high97.3Very high26 Ų2655.6 Ų55.616%0.1626%0.259CS..Hα-helixtrans-72.7-14.1177.474.70000112.8Y16 L17 I40Y16-T19 PolarHBondContact O-N 2.93Å; Y16-T19 PolarHBondContact O-OG1 3.28Å; L17-T19 VanDerWaalsContact C-N 3.31Å; L17-T19 PolarHBondContact O-N 3.17Å; T19-I40 HydrophobicContact CG2-CB 4.31Å; T19-I40 HydrophobicContact CG2-CG2 3.83Å
20R98.1Very high97.7Very high146 Ų14652.5 Ų52.555%0.55125%0.248SC*.Hα-helixtrans-90.8-14.5175.3-55.2-54.6-67.3-174-6.7113.4Y16 L17 L18 P22Y16-R20 HydrophobicContact CD1-CG 4.1Å; Y16-R20 HydrophobicContact CE1-CG 3.64Å; Y16-R20 HydrophobicContact CE2-CG 4.46Å; Y16-R20 PolarHBondContact O-N 3.4Å; L17-R20 WeakPolarHBondContact O-CB 3.15Å; L17-R20 PolarHBondContact O-N 3.47Å; L17-R20 VanDerWaalsContact O-N 3.12Å; L18-R20 PolarHBondContact O-N 3.22Å; R20-P22 WeakPolarHBondContact O-CD 3.42Å
21N98.1Very high98.1Very high30 Ų3048.2 Ų48.216%0.1623%0.232CC..  trans-88109176.3-174.1-24.9000109.6Q13 L17 L18 H23 L24 N25Q13-N21 PolarHBondContact OE1-ND2 3.13Å; L17-N21 PolarHBondContact O-N 3.25Å; L18-N21 PolarHBondContact O-N 3.37Å; N21-H23 PolarHBondContact O-N 3.16Å; N21-H23 VanDerWaalsContact O-N 3.16Å; N21-H23 VanDerWaalsContact OD1-CB 3.27Å; N21-H23 WeakPolarHBondContact OD1-CB 3.39Å; N21-H23 PolarHBondContact OD1-CD2 2.97Å; N21-H23 PolarHBondContact OD1-N 2.95Å; N21-L24 HydrophobicContact CB-CB 4.32Å; N21-L24 HydrophobicContact CB-CD1 4.28Å; N21-L24 HydrophobicContact CB-CG 4.4Å; N21-L24 PolarHBondContact O-N 3.37Å; N21-N25 WeakPolarHBondContact O-CB 3.28Å; N21-N25 PolarHBondContact O-N 3.21Å
22P98.1Very high98.2Very high21 Ų2150.7 Ų50.714%0.13624%0.244CC..THydrogen-bonded Turntrans-64.7-20.5-176.827.8-35.3000113.4R20 L24 Q79 E83R20-P22 WeakPolarHBondContact O-CD 3.42Å; P22-L24 VanDerWaalsContact C-N 3.31Å; P22-Q79 WeakPolarHBondContact CB-O 3.48Å; P22-E83 VanDerWaalsContact O-CB 3.31Å; P22-E83 WeakPolarHBondContact O-CB 3.32Å; P22-E83 PolarHBondContact O-N 3.42Å
23H97.6Very high98.3Very high35 Ų3548.3 Ų48.316%0.16223%0.234CC..THydrogen-bonded Turntrans-76.7-18177.3-49.2-59.7000113.3R9 N21 E83 E142 Q186R9-H23 PolarHBondContact NH1-O 3.44Å; R9-H23 VanDerWaalsContact NH1-O 3.16Å; N21-H23 PolarHBondContact O-N 3.16Å; N21-H23 VanDerWaalsContact O-N 3.16Å; N21-H23 VanDerWaalsContact OD1-CB 3.27Å; N21-H23 WeakPolarHBondContact OD1-CB 3.39Å; N21-H23 PolarHBondContact OD1-CD2 2.97Å; N21-H23 PolarHBondContact OD1-N 2.95Å; H23-E83 IonicContact CE1-OE1 2.69Å; H23-E83 PolarHBondContact CE1-OE1 3.45Å; H23-E83 IonicContact CE1-OE2 2.96Å; H23-E83 IonicContact CG-OE2 3.2Å; H23-E83 IonicContact ND1-OE1 2.63Å; H23-E83 PolarHBondContact ND1-OE1 2.87Å; H23-E83 IonicContact ND1-OE2 3.03Å; H23-E83 PolarHBondContact ND1-OE2 3.33Å; H23-E142 IonicContact CD2-OE1 3.14Å; H23-Q186 HydrophobicContact CB-CG 4.45Å; H23-Q186 WeakPolarHBondContact ND1-CG 3.35Å
24L98.2Very high98.4Very high6 Ų646.1 Ų46.13%0.03122%0.223CC..THydrogen-bonded Turntrans-116.5-29.8-177-61.3177.3000112.5T11 Q13 L18 N21 P22 K26 F30 I552T11-L24 HydrophobicContact CG2-CD1 4.27Å; T11-L24 HydrophobicContact CG2-CD2 4.34Å; Q13-L24 HydrophobicContact CB-CD1 4.11Å; L18-L24 HydrophobicContact CG-CB 4.24Å; L18-L24 HydrophobicContact CG-CD1 4.49Å; N21-L24 HydrophobicContact CB-CB 4.32Å; N21-L24 HydrophobicContact CB-CD1 4.28Å; N21-L24 HydrophobicContact CB-CG 4.4Å; N21-L24 PolarHBondContact O-N 3.37Å; P22-L24 VanDerWaalsContact C-N 3.31Å; L24-K26 PolarHBondContact O-N 3.32Å; L24-F30 VanDerWaalsContact O-CZ 3.31Å; L24-F30 WeakPolarHBondContact O-CZ 3.35Å; L24-I552 HydrophobicContact CD2-CG2 4.27Å
25N98.7Very high98.4Very high5 Ų542.2 Ų42.23%0.02721%0.208CC..  trans-65.3128.4-177.2-178.737.8000111.7N21 D27 R81 N82N21-N25 WeakPolarHBondContact O-CB 3.28Å; N21-N25 PolarHBondContact O-N 3.21Å; N25-D27 PolarHBondContact ND2-OD1 2.71Å; N25-D27 PolarHBondContact OD1-N 3.08Å; N25-R81 WeakPolarHBondContact CB-O 3.22Å; N25-R81 PolarHBondContact ND2-O 2.98Å; N25-N82 VanDerWaalsContact O-CG 3.3Å; N25-N82 PolarHBondContact O-OD1 3.39Å
26K98.8Very high98.4Very high13 Ų1346.5 Ų46.56%0.05723%0.225CC..  trans-109.92.5174.8-51.3-175-176.7-179.50112.7L24 L28 A29 F30 E34 Q54 Y549 D550L24-K26 PolarHBondContact O-N 3.32Å; K26-L28 PolarHBondContact O-N 3.47Å; K26-A29 HydrophobicContact CB-CB 4.19Å; K26-A29 WeakPolarHBondContact O-CB 3.3Å; K26-A29 PolarHBondContact O-N 3.08Å; K26-F30 HydrophobicContact CB-CD1 3.9Å; K26-F30 HydrophobicContact CB-CD2 3.96Å; K26-F30 HydrophobicContact CB-CE1 3.84Å; K26-F30 HydrophobicContact CB-CE2 3.93Å; K26-F30 HydrophobicContact CB-CG 3.94Å; K26-F30 HydrophobicContact CB-CZ 3.85Å; K26-F30 HydrophobicContact CD-CD1 3.75Å; K26-F30 HydrophobicContact CD-CE1 3.64Å; K26-F30 HydrophobicContact CD-CZ 4.38Å; K26-F30 HydrophobicContact CG-CD1 3.92Å; K26-F30 HydrophobicContact CG-CE1 3.5Å; K26-F30 VanDerWaalsContact CG-CE1 3.5Å; K26-F30 HydrophobicContact CG-CE2 4.33Å; K26-F30 HydrophobicContact CG-CG 4.46Å; K26-F30 HydrophobicContact CG-CZ 3.72Å; K26-F30 VanDerWaalsContact N-CZ 3.28Å; K26-E34 IonicContact NZ-OE1 2.71Å; K26-E34 PolarHBondContact NZ-OE1 2.89Å; K26-E34 IonicContact NZ-OE2 3.16Å; K26-Q54 PolarHBondContact O-NE2 2.86Å; K26-Y549 HydrophobicContact CB-CD1 4.03Å; K26-Y549 HydrophobicContact CB-CE1 3.81Å; K26-Y549 HydrophobicContact CB-CE2 4.44Å; K26-Y549 HydrophobicContact CB-CG 4.42Å; K26-Y549 HydrophobicContact CD-CD1 3.93Å; K26-Y549 HydrophobicContact CD-CD2 4.46Å; K26-Y549 HydrophobicContact CD-CG 3.86Å; K26-Y549 HydrophobicContact CG-CD1 3.56Å; K26-Y549 HydrophobicContact CG-CE1 3.81Å; K26-Y549 HydrophobicContact CG-CG 4.01Å; K26-D550 WeakPolarHBondContact CE-O 3.4Å; K26-D550 PolarHBondContact NZ-O 3.47Å
27D98.7Very high98.4Very high29 Ų2945.4 Ų45.416%0.15523%0.225CC..G310 helixtrans47.8-127.6-170-57.3-56.5000111.3N25 A29 F30 L44 R81 N82N25-D27 PolarHBondContact ND2-OD1 2.71Å; N25-D27 PolarHBondContact OD1-N 3.08Å; D27-A29 PolarHBondContact O-N 3.02Å; D27-F30 WeakPolarHBondContact O-CD2 3.41Å; D27-F30 PolarHBondContact O-N 2.75Å; D27-L44 WeakPolarHBondContact O-CD1 3.48Å; D27-R81 IonicContact OD2-NE 3.86Å; D27-N82 WeakPolarHBondContact OD2-CB 3.13Å; D27-N82 PolarHBondContact OD2-ND2 3.44Å
28L98.6Very high98.4Very high12 Ų1240 Ų406%0.06320%0.197CC..G310 helixtrans-74-3.8-179.1-59.8-179.7000114.3K26 F30 R35 L44 P45 F48 I49K26-L28 PolarHBondContact O-N 3.47Å; L28-F30 VanDerWaalsContact C-N 3.29Å; L28-R35 PolarHBondContact O-NH2 3.3Å; L28-R35 VanDerWaalsContact O-NH2 3.14Å; L28-L44 HydrophobicContact CD2-CB 4.31Å; L28-P45 HydrophobicContact CD2-CB 4.06Å; L28-P45 HydrophobicContact CD2-CG 4.11Å; L28-F48 WeakPolarHBondContact O-CA 3.48Å; L28-I49 HydrophobicContact CB-CD1 3.94Å; L28-I49 HydrophobicContact CB-CG1 3.6Å; L28-I49 HydrophobicContact CD1-CD1 4Å; L28-I49 HydrophobicContact CD1-CG1 4.42Å; L28-I49 PolarHBondContact O-N 2.9Å; L28-I49 VanDerWaalsContact O-N 3.13Å
29A98.6Very high98.4Very high20 Ų2045.3 Ų45.317%0.16523%0.225CC..G310 helixtrans-80.4-10.3172.700000113.1K26 D27 T31 I49 Y549K26-A29 HydrophobicContact CB-CB 4.19Å; K26-A29 WeakPolarHBondContact O-CB 3.3Å; K26-A29 PolarHBondContact O-N 3.08Å; D27-A29 PolarHBondContact O-N 3.02Å; A29-T31 PolarHBondContact O-N 3.02Å; A29-I49 VanDerWaalsContact CA-O 3.3Å; A29-I49 WeakPolarHBondContact CA-O 3.39Å; A29-I49 WeakPolarHBondContact CB-O 3.45Å; A29-Y549 HydrophobicContact CB-CD2 3.99Å; A29-Y549 HydrophobicContact CB-CE2 3.41Å; A29-Y549 VanDerWaalsContact CB-CE2 3.41Å
30F98.7Very high98.5Very high0 Ų044.1 Ų44.10%022%0.217CC..SBendtrans-58.9125.9166.7-76.7-59.6000110.4L18 L24 K26 D27 L28 E34 R35 L38 I40 L44 F48 I552L18-F30 HydrophobicContact CD2-CE1 4.25Å; L18-F30 HydrophobicContact CD2-CE2 4.02Å; L18-F30 HydrophobicContact CD2-CZ 3.47Å; L18-F30 VanDerWaalsContact CD2-CZ 3.47Å; L24-F30 VanDerWaalsContact O-CZ 3.31Å; L24-F30 WeakPolarHBondContact O-CZ 3.35Å; K26-F30 HydrophobicContact CB-CD1 3.9Å; K26-F30 HydrophobicContact CB-CD2 3.96Å; K26-F30 HydrophobicContact CB-CE1 3.84Å; K26-F30 HydrophobicContact CB-CE2 3.93Å; K26-F30 HydrophobicContact CB-CG 3.94Å; K26-F30 HydrophobicContact CB-CZ 3.85Å; K26-F30 HydrophobicContact CD-CD1 3.75Å; K26-F30 HydrophobicContact CD-CE1 3.64Å; K26-F30 HydrophobicContact CD-CZ 4.38Å; K26-F30 HydrophobicContact CG-CD1 3.92Å; K26-F30 HydrophobicContact CG-CE1 3.5Å; K26-F30 VanDerWaalsContact CG-CE1 3.5Å; K26-F30 HydrophobicContact CG-CE2 4.33Å; K26-F30 HydrophobicContact CG-CG 4.46Å; K26-F30 HydrophobicContact CG-CZ 3.72Å; K26-F30 VanDerWaalsContact N-CZ 3.28Å; D27-F30 WeakPolarHBondContact O-CD2 3.41Å; D27-F30 PolarHBondContact O-N 2.75Å; L28-F30 VanDerWaalsContact C-N 3.29Å; F30-E34 WeakPolarHBondContact CA-OE2 3.47Å; F30-E34 HydrophobicContact CB-CB 4.48Å; F30-E34 HydrophobicContact CD1-CB 4.06Å; F30-R35 HydrophobicContact CB-CG 3.73Å; F30-R35 PolarHBondContact O-NE 3.3Å; F30-R35 PolarHBondContact O-NH2 3.29Å; F30-R35 VanDerWaalsContact O-NH2 3.1Å; F30-L38 HydrophobicContact CD1-CD1 4.23Å; F30-L38 HydrophobicContact CE1-CD1 3.92Å; F30-I40 HydrophobicContact CB-CD1 4.37Å; F30-I40 HydrophobicContact CD1-CD1 4.31Å; F30-I40 HydrophobicContact CD2-CD1 3.53Å; F30-I40 HydrophobicContact CE2-CD1 3.77Å; F30-I40 HydrophobicContact CG-CD1 3.83Å; F30-I40 HydrophobicContact CZ-CD1 4.28Å; F30-L44 HydrophobicContact CD2-CD1 3.97Å; F30-F48 WeakPolarHBondContact O-CD1 3.37Å; F30-I552 HydrophobicContact CE1-CD1 3.81Å; F30-I552 HydrophobicContact CZ-CD1 4.34Å
31T98.6Very high98.5Very high64 Ų6442.8 Ų42.839%0.39322%0.217SC..  trans-67.4166.7174.773.50000111.2A29 E33 E34 R35A29-T31 PolarHBondContact O-N 3.02Å; T31-E33 VanDerWaalsContact C-N 3.32Å; T31-E33 PolarHBondContact O-N 3.14Å; T31-E34 PolarHBondContact N-OE2 3.46Å; T31-E34 PolarHBondContact O-N 3.46Å; T31-E34 WeakPolarHBondContact OG1-CG 3.4Å; T31-E34 PolarHBondContact OG1-N 3.39Å; T31-E34 VanDerWaalsContact OG1-N 3.08Å; T31-R35 VanDerWaalsContact O-CG 3.25Å; T31-R35 WeakPolarHBondContact O-CG 3.44Å; T31-R35 PolarHBondContact O-N 3.4Å
32L98.7Very high98.5Very high76 Ų7644.6 Ų44.640%0.39824%0.242SC..Hα-helixtrans-60.9-43.6175.7178.959.3000111.7R35 Q36 F48L32-R35 PolarHBondContact O-N 2.83Å; L32-Q36 HydrophobicContact CD1-CG 4.29Å; L32-Q36 WeakPolarHBondContact O-CG 2.83Å; L32-Q36 PolarHBondContact O-N 2.55Å; L32-F48 HydrophobicContact CB-CE1 3.85Å; L32-F48 HydrophobicContact CB-CZ 3.86Å; L32-F48 HydrophobicContact CD1-CZ 4.06Å; L32-F48 HydrophobicContact CG-CZ 4.47Å
33E98.6Very high98.5Very high123 Ų12348 Ų4858%0.57526%0.259SS*.Hα-helixtrans-58.5-50176.2-180-177-163.500111.1T31 R35 Q36 Q37 L553T31-E33 VanDerWaalsContact C-N 3.32Å; T31-E33 PolarHBondContact O-N 3.14Å; E33-R35 VanDerWaalsContact C-N 3.29Å; E33-R35 PolarHBondContact O-N 3Å; E33-Q36 PolarHBondContact O-N 3Å; E33-Q37 HydrophobicContact CG-CG 4.3Å; E33-Q37 WeakPolarHBondContact O-CB 3.41Å; E33-Q37 WeakPolarHBondContact O-CG 3.41Å; E33-Q37 PolarHBondContact O-N 3.01Å; E33-L553 HydrophobicContact CG-CD1 4.11Å
34E98.4Very high98.6Very high14 Ų1448 Ų487%0.06526%0.26CS..Hα-helixtrans-57.3-44.9176.4-74.9-179.9129.400111K26 F30 T31 Q36 Q37 L38 L553K26-E34 IonicContact NZ-OE1 2.71Å; K26-E34 PolarHBondContact NZ-OE1 2.89Å; K26-E34 IonicContact NZ-OE2 3.16Å; F30-E34 WeakPolarHBondContact CA-OE2 3.47Å; F30-E34 HydrophobicContact CB-CB 4.48Å; F30-E34 HydrophobicContact CD1-CB 4.06Å; T31-E34 PolarHBondContact N-OE2 3.46Å; T31-E34 PolarHBondContact O-N 3.46Å; T31-E34 WeakPolarHBondContact OG1-CG 3.4Å; T31-E34 PolarHBondContact OG1-N 3.39Å; T31-E34 VanDerWaalsContact OG1-N 3.08Å; E34-Q36 VanDerWaalsContact C-N 3.32Å; E34-Q36 PolarHBondContact O-N 3.13Å; E34-Q37 PolarHBondContact O-N 2.88Å; E34-L38 HydrophobicContact CB-CD1 4.15Å; E34-L38 WeakPolarHBondContact O-CB 3.29Å; E34-L38 WeakPolarHBondContact O-CD1 3.49Å; E34-L38 WeakPolarHBondContact O-CG 3.14Å; E34-L38 PolarHBondContact O-N 3.41Å; E34-L553 HydrophobicContact CG-CD1 3.85Å; E34-L553 HydrophobicContact CG-CD2 4.45Å; E34-L553 HydrophobicContact CG-CG 4Å
35R98.8Very high98.6Very high3 Ų351.3 Ų51.31%0.01128%0.282CS..Hα-helixtrans-62.6-39.3-179.3-69.2178.4-158.1-164.95.3112.8L28 F30 T31 L32 E33 N39 I40 H41 P45 S47 F48L28-R35 PolarHBondContact O-NH2 3.3Å; L28-R35 VanDerWaalsContact O-NH2 3.14Å; F30-R35 HydrophobicContact CB-CG 3.73Å; F30-R35 PolarHBondContact O-NE 3.3Å; F30-R35 PolarHBondContact O-NH2 3.29Å; F30-R35 VanDerWaalsContact O-NH2 3.1Å; T31-R35 VanDerWaalsContact O-CG 3.25Å; T31-R35 WeakPolarHBondContact O-CG 3.44Å; T31-R35 PolarHBondContact O-N 3.4Å; L32-R35 PolarHBondContact O-N 2.83Å; E33-R35 VanDerWaalsContact C-N 3.29Å; E33-R35 PolarHBondContact O-N 3Å; R35-N39 PolarHBondContact O-N 3.2Å; R35-I40 HydrophobicContact CB-CG1 3.94Å; R35-I40 HydrophobicContact CG-CD1 4.07Å; R35-I40 HydrophobicContact CG-CG1 3.96Å; R35-I40 PolarHBondContact O-N 2.88Å; R35-H41 HydrophobicContact CB-CB 4.12Å; R35-H41 PolarHBondContact O-N 3.11Å; R35-P45 PolarHBondContact NH1-O 2.99Å; R35-S47 PolarHBondContact NH2-O 2.92Å; R35-F48 VanDerWaalsContact CZ-CE1 3.43Å
36Q98.6Very high98.6Very high104 Ų10457.1 Ų57.149%0.48632%0.32SS..Hα-helixtrans-69.6-51.1178.2-71.5170.5-22.500110.9L32 E33 E34 L38 N39 H41L32-Q36 HydrophobicContact CD1-CG 4.29Å; L32-Q36 WeakPolarHBondContact O-CG 2.83Å; L32-Q36 PolarHBondContact O-N 2.55Å; E33-Q36 PolarHBondContact O-N 3Å; E34-Q36 VanDerWaalsContact C-N 3.32Å; E34-Q36 PolarHBondContact O-N 3.13Å; Q36-L38 VanDerWaalsContact C-N 3.31Å; Q36-L38 PolarHBondContact O-N 3.12Å; Q36-N39 PolarHBondContact O-N 3.01Å; Q36-H41 HydrophobicContact CG-CB 4.39Å
37Q98.3Very high98.5Very high114 Ų11458.7 Ų58.753%0.53333%0.333SS..Hα-helixtrans-67.1-29.6-178.1-68.6-63.1-28.900113.3E33 E34 L553E33-Q37 HydrophobicContact CG-CG 4.3Å; E33-Q37 WeakPolarHBondContact O-CB 3.41Å; E33-Q37 WeakPolarHBondContact O-CG 3.41Å; E33-Q37 PolarHBondContact O-N 3.01Å; E34-Q37 PolarHBondContact O-N 2.88Å; Q37-L553 HydrophobicContact CB-CD2 3.59Å; Q37-L553 HydrophobicContact CG-CD2 4.33Å
38L98.5Very high98.5Very high0 Ų062.2 Ų62.20%035%0.347CS..THydrogen-bonded Turntrans-91.91.9178.6-60170.7000113.5G15 L18 F30 E34 Q36 I40 I552 L553G15-L38 PolarHBondContact N-O 2.87Å; L18-L38 HydrophobicContact CD1-CB 4.34Å; L18-L38 HydrophobicContact CD1-CD1 4.11Å; L18-L38 HydrophobicContact CD1-CD2 3.93Å; L18-L38 HydrophobicContact CD1-CG 4.35Å; L18-L38 HydrophobicContact CD2-CD1 4.46Å; F30-L38 HydrophobicContact CD1-CD1 4.23Å; F30-L38 HydrophobicContact CE1-CD1 3.92Å; E34-L38 HydrophobicContact CB-CD1 4.15Å; E34-L38 WeakPolarHBondContact O-CB 3.29Å; E34-L38 WeakPolarHBondContact O-CD1 3.49Å; E34-L38 WeakPolarHBondContact O-CG 3.14Å; E34-L38 PolarHBondContact O-N 3.41Å; Q36-L38 VanDerWaalsContact C-N 3.31Å; Q36-L38 PolarHBondContact O-N 3.12Å; L38-I40 HydrophobicContact CB-CD1 4.48Å; L38-I40 HydrophobicContact CB-CG1 4.28Å; L38-I40 PolarHBondContact O-N 2.92Å; L38-I552 HydrophobicContact CD1-CD1 3.68Å; L38-I552 HydrophobicContact CD1-CG1 3.98Å; L38-L553 HydrophobicContact CD2-CD2 4.1Å; L38-L553 HydrophobicContact CG-CD2 4.04Å
39N98.6Very high98.5Very high111 Ų11163.1 Ų63.159%0.59435%0.351SS*.THydrogen-bonded Turntrans59.738.3-179.1-45.5103.3000114.1G15 R35 Q36G15-N39 WeakPolarHBondContact CA-O 3.48Å; R35-N39 PolarHBondContact O-N 3.2Å; Q36-N39 PolarHBondContact O-N 3.01Å
40I98.8Very high98.5Very high0 Ų064.9 Ų64.90%036%0.362CS..  trans-117.90.3178.262172.9000113.2G15 L18 T19 F30 R35 L38 G42 L43 L44G15-I40 VanDerWaalsContact O-CG2 3.22Å; G15-I40 WeakPolarHBondContact O-CG2 3.4Å; L18-I40 HydrophobicContact CD2-CD1 4.48Å; T19-I40 HydrophobicContact CG2-CB 4.31Å; T19-I40 HydrophobicContact CG2-CG2 3.83Å; F30-I40 HydrophobicContact CB-CD1 4.37Å; F30-I40 HydrophobicContact CD1-CD1 4.31Å; F30-I40 HydrophobicContact CD2-CD1 3.53Å; F30-I40 HydrophobicContact CE2-CD1 3.77Å; F30-I40 HydrophobicContact CG-CD1 3.83Å; F30-I40 HydrophobicContact CZ-CD1 4.28Å; R35-I40 HydrophobicContact CB-CG1 3.94Å; R35-I40 HydrophobicContact CG-CD1 4.07Å; R35-I40 HydrophobicContact CG-CG1 3.96Å; R35-I40 PolarHBondContact O-N 2.88Å; L38-I40 HydrophobicContact CB-CD1 4.48Å; L38-I40 HydrophobicContact CB-CG1 4.28Å; L38-I40 PolarHBondContact O-N 2.92Å; I40-G42 PolarHBondContact O-N 3.35Å; I40-L43 HydrophobicContact CB-CD1 4.21Å; I40-L43 HydrophobicContact CG2-CD1 4.22Å; I40-L43 WeakPolarHBondContact O-CB 3.48Å; I40-L43 PolarHBondContact O-N 3.11Å; I40-L44 HydrophobicContact CD1-CD1 4.29Å
41H98.6Very high98.5Very high119 Ų11965.4 Ų65.455%0.55137%0.365SS*.THydrogen-bonded Turntrans-58.5131.4172.9-172.972.6000110.3R35 Q36R35-H41 HydrophobicContact CB-CB 4.12Å; R35-H41 PolarHBondContact O-N 3.11Å; Q36-H41 HydrophobicContact CG-CB 4.39Å
42G98.1Very high98.5Very high67 Ų6767.6 Ų67.669%0.69137%0.37SS*.THydrogen-bonded Turntrans90.8-19.4-172.700000115.1I40 L44I40-G42 PolarHBondContact O-N 3.35Å; G42-L44 VanDerWaalsContact C-N 3.35Å
43L98.6Very high98.5Very high94 Ų9467.7 Ų67.749%0.49237%0.371SS..THydrogen-bonded Turntrans-81.4-15.9175.3-58-177.1000113.4I40I40-L43 HydrophobicContact CB-CD1 4.21Å; I40-L43 HydrophobicContact CG2-CD1 4.22Å; I40-L43 WeakPolarHBondContact O-CB 3.48Å; I40-L43 PolarHBondContact O-N 3.11Å
44L98.6Very high98.5Very high33 Ų3362.2 Ų62.217%0.17335%0.345CS..SBendtrans-121.2147.3-177.1-66.9170.9000110.2D27 L28 F30 I40 G42D27-L44 WeakPolarHBondContact O-CD1 3.48Å; L28-L44 HydrophobicContact CD2-CB 4.31Å; F30-L44 HydrophobicContact CD2-CD1 3.97Å; I40-L44 HydrophobicContact CD1-CD1 4.29Å; G42-L44 VanDerWaalsContact C-N 3.35Å
45P98.6Very high98.5Very high76 Ų7662.5 Ų62.549%0.49435%0.348SS..  trans-48.6147171.4-28.932.8000113.1L28 R35 S47L28-P45 HydrophobicContact CD2-CB 4.06Å; L28-P45 HydrophobicContact CD2-CG 4.11Å; R35-P45 PolarHBondContact NH1-O 2.99Å; P45-S47 PolarHBondContact O-N 3.42Å
46P98.1Very high98.5Very high128 Ų12866.5 Ų66.583%0.83137%0.369SS*.SBendtrans-77.448-176.834.7-38000112.4
47S98.3Very high98.5Very high45 Ų4567.4 Ų67.432%0.31537%0.368SS..  trans-128.5144.6173.956.90000109.8R35 P45R35-S47 PolarHBondContact NH2-O 2.92Å; P45-S47 PolarHBondContact O-N 3.42Å
48F98.5Very high98.5Very high104 Ų10462.5 Ų62.546%0.45635%0.346SS..  trans-124120.4-179.5-51.4-86.5000107.1L28 F30 L32 R35L28-F48 WeakPolarHBondContact O-CA 3.48Å; F30-F48 WeakPolarHBondContact O-CD1 3.37Å; L32-F48 HydrophobicContact CB-CE1 3.85Å; L32-F48 HydrophobicContact CB-CZ 3.86Å; L32-F48 HydrophobicContact CD1-CZ 4.06Å; L32-F48 HydrophobicContact CG-CZ 4.47Å; R35-F48 VanDerWaalsContact CZ-CE1 3.43Å
49I98.2Very high98.5Very high31 Ų3163.7 Ų63.716%0.15935%0.353CS..  trans-133145.9-17360.7171.6000110.7L28 A29 I53 Q54L28-I49 HydrophobicContact CB-CD1 3.94Å; L28-I49 HydrophobicContact CB-CG1 3.6Å; L28-I49 HydrophobicContact CD1-CD1 4Å; L28-I49 HydrophobicContact CD1-CG1 4.42Å; L28-I49 PolarHBondContact O-N 2.9Å; L28-I49 VanDerWaalsContact O-N 3.13Å; A29-I49 VanDerWaalsContact CA-O 3.3Å; A29-I49 WeakPolarHBondContact CA-O 3.39Å; A29-I49 WeakPolarHBondContact CB-O 3.45Å; I49-I53 HydrophobicContact CB-CB 4.01Å; I49-I53 HydrophobicContact CB-CG2 3.87Å; I49-I53 HydrophobicContact CD1-CB 4.48Å; I49-I53 HydrophobicContact CD1-CG2 3.98Å; I49-I53 HydrophobicContact CG1-CG2 4.48Å; I49-I53 HydrophobicContact CG2-CG2 4Å; I49-Q54 HydrophobicContact CD1-CG 3.54Å; I49-Q54 HydrophobicContact CG1-CG 3.83Å
50S98.4Very high98.5Very high56 Ų5664.3 Ų64.339%0.39235%0.35SS..  trans-68.9165.3175.581.30000111.4E52 I53 Q54S50-E52 WeakPolarHBondContact CB-OE2 3.35Å; S50-E52 PolarHBondContact O-N 2.89Å; S50-E52 PolarHBondContact OG-N 3.05Å; S50-E52 PolarHBondContact OG-OE2 2.84Å; S50-I53 PolarHBondContact O-N 3.15Å; S50-I53 PolarHBondContact OG-N 3.01Å; S50-Q54 PolarHBondContact O-N 3.41Å; S50-Q54 VanDerWaalsContact O-N 3.12Å
51Q98.3Very high98.5Very high12 Ų1267.8 Ų67.86%0.05637%0.369CS..Hα-helixtrans-61.4-32.6178-159.1-179.739.300111.6Q54 V55 L85 K88 T547 Y549Q51-Q54 WeakPolarHBondContact O-CB 3.21Å; Q51-Q54 PolarHBondContact O-N 3.05Å; Q51-V55 WeakPolarHBondContact O-CG2 3.47Å; Q51-V55 PolarHBondContact O-N 3.04Å; Q51-L85 HydrophobicContact CG-CD1 4.24Å; Q51-K88 HydrophobicContact CG-CB 4.4Å; Q51-K88 HydrophobicContact CG-CG 4.03Å; Q51-K88 VanDerWaalsContact OE1-CD 3.29Å; Q51-K88 VanDerWaalsContact OE1-CE 3.31Å; Q51-T547 PolarHBondContact NE2-O 3.3Å; Q51-T547 PolarHBondContact OE1-O 3.45Å; Q51-Y549 HydrophobicContact CB-CD2 4.43Å; Q51-Y549 HydrophobicContact CB-CE2 3.96Å; Q51-Y549 HydrophobicContact CG-CD2 4.37Å; Q51-Y549 HydrophobicContact CG-CE2 3.7Å
52E98.6Very high98.5Very high109 Ų10962.6 Ų62.651%0.50935%0.345SS..Hα-helixtrans-65-40.1177.3-60.167.7-143.400111.6S50 Q54 V55 L56S50-E52 WeakPolarHBondContact CB-OE2 3.35Å; S50-E52 PolarHBondContact O-N 2.89Å; S50-E52 PolarHBondContact OG-N 3.05Å; S50-E52 PolarHBondContact OG-OE2 2.84Å; E52-Q54 VanDerWaalsContact C-N 3.31Å; E52-V55 PolarHBondContact O-N 3.43Å; E52-L56 PolarHBondContact O-N 2.97Å
53I98.6Very high98.5Very high79 Ų7964.7 Ų64.741%0.40534%0.336SS..Hα-helixtrans-69.6-33175.2-60.2-60.9000111I49 S50 L56 R57I49-I53 HydrophobicContact CB-CB 4.01Å; I49-I53 HydrophobicContact CB-CG2 3.87Å; I49-I53 HydrophobicContact CD1-CB 4.48Å; I49-I53 HydrophobicContact CD1-CG2 3.98Å; I49-I53 HydrophobicContact CG1-CG2 4.48Å; I49-I53 HydrophobicContact CG2-CG2 4Å; S50-I53 PolarHBondContact O-N 3.15Å; S50-I53 PolarHBondContact OG-N 3.01Å; I53-L56 PolarHBondContact O-N 2.97Å; I53-R57 PolarHBondContact O-N 3.21Å; I53-R57 VanDerWaalsContact O-N 3.09Å
54Q98.8Very high98.5Very high7 Ų769.4 Ų69.43%0.03335%0.348CS..Hα-helixtrans-64.7-44.2171.3-65178.5-58.900111.5K26 I49 S50 Q51 E52 R57 V58 L85 Y549K26-Q54 PolarHBondContact O-NE2 2.86Å; I49-Q54 HydrophobicContact CD1-CG 3.54Å; I49-Q54 HydrophobicContact CG1-CG 3.83Å; S50-Q54 PolarHBondContact O-N 3.41Å; S50-Q54 VanDerWaalsContact O-N 3.12Å; Q51-Q54 WeakPolarHBondContact O-CB 3.21Å; Q51-Q54 PolarHBondContact O-N 3.05Å; E52-Q54 VanDerWaalsContact C-N 3.31Å; Q54-R57 WeakPolarHBondContact O-CB 3.42Å; Q54-R57 PolarHBondContact O-N 2.85Å; Q54-V58 WeakPolarHBondContact O-CG2 3.42Å; Q54-V58 PolarHBondContact O-N 3.19Å; Q54-L85 HydrophobicContact CB-CD1 3.55Å; Q54-L85 HydrophobicContact CB-CD2 3.73Å; Q54-L85 HydrophobicContact CB-CG 4.3Å; Q54-L85 HydrophobicContact CG-CD2 4.46Å; Q54-Y549 PolarHBondContact NE2-OH 3.4Å; Q54-Y549 PolarHBondContact OE1-OH 3.08Å
55V98.8Very high98.5Very high20 Ų2070.3 Ų70.312%0.12135%0.352CS..Hα-helixtrans-57.9-49.4174.3170.30000110.1Q51 E52 R57 V58 V59 L85 K88 V89Q51-V55 WeakPolarHBondContact O-CG2 3.47Å; Q51-V55 PolarHBondContact O-N 3.04Å; E52-V55 PolarHBondContact O-N 3.43Å; V55-R57 VanDerWaalsContact C-N 3.25Å; V55-R57 PolarHBondContact O-N 2.98Å; V55-V58 PolarHBondContact O-N 3.28Å; V55-V59 HydrophobicContact CG1-CG2 4.05Å; V55-V59 WeakPolarHBondContact O-CG2 3.42Å; V55-V59 PolarHBondContact O-N 3.35Å; V55-L85 HydrophobicContact CG2-CD1 3.84Å; V55-K88 HydrophobicContact CG2-CB 4.26Å; V55-K88 HydrophobicContact CG2-CG 3.71Å; V55-V89 HydrophobicContact CB-CG2 4.4Å; V55-V89 HydrophobicContact CG1-CG2 4.32Å; V55-V89 HydrophobicContact CG2-CG2 3.99Å
56L98.6Very high98.4Very high88 Ų8874.2 Ų74.246%0.46137%0.369SS..Hα-helixtrans-53.1-43.6176.7175.863.5000112E52 I53 K60E52-L56 PolarHBondContact O-N 2.97Å; I53-L56 PolarHBondContact O-N 2.97Å; L56-K60 HydrophobicContact CD1-CD 4.47Å; L56-K60 HydrophobicContact CD1-CG 4.31Å; L56-K60 WeakPolarHBondContact O-CB 3.41Å; L56-K60 WeakPolarHBondContact O-CG 3.27Å; L56-K60 PolarHBondContact O-N 3.43Å
57R98.7Very high98.4Very high123 Ų12370 Ų7046%0.46434%0.343SS..Hα-helixtrans-63.8-44.3177.6-174.7-179.1-64169.30.4111.6I53 Q54 V55 N61I53-R57 PolarHBondContact O-N 3.21Å; I53-R57 VanDerWaalsContact O-N 3.09Å; Q54-R57 WeakPolarHBondContact O-CB 3.42Å; Q54-R57 PolarHBondContact O-N 2.85Å; V55-R57 VanDerWaalsContact C-N 3.25Å; V55-R57 PolarHBondContact O-N 2.98Å; R57-N61 PolarHBondContact O-N 2.86Å; R57-N61 PolarHBondContact O-ND2 3.03Å
58V98.8Very high98.3Very high10 Ų1071.5 Ų71.56%0.06135%0.347CS..Hα-helixtrans-62.8-48.9178174.20000110.4Q54 V55 K60 N61 F62 L78 L85 V89Q54-V58 WeakPolarHBondContact O-CG2 3.42Å; Q54-V58 PolarHBondContact O-N 3.19Å; V55-V58 PolarHBondContact O-N 3.28Å; V58-K60 PolarHBondContact O-N 2.99Å; V58-N61 WeakPolarHBondContact O-CB 3.48Å; V58-N61 PolarHBondContact O-N 3.39Å; V58-F62 PolarHBondContact O-N 3.03Å; V58-L78 HydrophobicContact CG1-CD2 3.82Å; V58-L78 HydrophobicContact CG2-CD1 4.33Å; V58-L78 HydrophobicContact CG2-CD2 3.97Å; V58-L85 HydrophobicContact CG2-CD2 4.21Å; V58-V89 HydrophobicContact CB-CG2 3.98Å; V58-V89 HydrophobicContact CG1-CG1 4.11Å; V58-V89 HydrophobicContact CG1-CG2 3.92Å; V58-V89 HydrophobicContact CG2-CG2 4.29Å
59V98.7Very high98.3Very high25 Ų2568.2 Ų68.215%0.15233%0.333CS..Hα-helixtrans-61.6-42-178.5176.70000111.5V55 N61 F62 E63 F97V55-V59 HydrophobicContact CG1-CG2 4.05Å; V55-V59 WeakPolarHBondContact O-CG2 3.42Å; V55-V59 PolarHBondContact O-N 3.35Å; V59-N61 VanDerWaalsContact C-N 3.26Å; V59-N61 PolarHBondContact O-N 3.03Å; V59-F62 WeakPolarHBondContact O-CB 3.48Å; V59-F62 PolarHBondContact O-N 2.67Å; V59-F62 VanDerWaalsContact O-N 3.15Å; V59-E63 HydrophobicContact CG1-CG 4.27Å; V59-E63 WeakPolarHBondContact CG1-OE1 3.45Å; V59-E63 WeakPolarHBondContact O-CG 3.43Å; V59-E63 PolarHBondContact O-N 2.67Å; V59-F97 HydrophobicContact CG2-CZ 4.09Å
60K98.6Very high98.3Very high125 Ų12570 Ų7054%0.54334%0.343SS..Hα-helixtrans-60.7-33.4173.7-79.4-168.6175.1-170.60113.4L56 V58 R64L56-K60 HydrophobicContact CD1-CD 4.47Å; L56-K60 HydrophobicContact CD1-CG 4.31Å; L56-K60 WeakPolarHBondContact O-CB 3.41Å; L56-K60 WeakPolarHBondContact O-CG 3.27Å; L56-K60 PolarHBondContact O-N 3.43Å; V58-K60 PolarHBondContact O-N 2.99Å; K60-R64 WeakPolarHBondContact O-CD 3.34Å; K60-R64 WeakPolarHBondContact O-CG 3.38Å
61N98.7Very high98.3Very high73 Ų7369.9 Ų69.939%0.3933%0.334SS..Hα-helixtrans-73.5-43174.2-77-80.1000110.7R57 V58 V59 E63 R64 L65 L74R57-N61 PolarHBondContact O-N 2.86Å; R57-N61 PolarHBondContact O-ND2 3.03Å; V58-N61 WeakPolarHBondContact O-CB 3.48Å; V58-N61 PolarHBondContact O-N 3.39Å; V59-N61 VanDerWaalsContact C-N 3.26Å; V59-N61 PolarHBondContact O-N 3.03Å; N61-E63 VanDerWaalsContact C-N 3.33Å; N61-E63 PolarHBondContact O-N 2.93Å; N61-R64 PolarHBondContact O-N 3.41Å; N61-L65 WeakPolarHBondContact O-CG 3.44Å; N61-L65 PolarHBondContact O-N 2.89Å; N61-L74 HydrophobicContact CB-CD1 4.48Å; N61-L74 HydrophobicContact CB-CD2 4.15Å
62F98.6Very high98.3Very high10 Ų1069.9 Ų69.94%0.04433%0.333CS..Hα-helixtrans-56.3-44.3177.3179.4-81.7000112.7V58 V59 R64 L65 R71 L74 L75 K96 F97 I100V58-F62 PolarHBondContact O-N 3.03Å; V59-F62 WeakPolarHBondContact O-CB 3.48Å; V59-F62 PolarHBondContact O-N 2.67Å; V59-F62 VanDerWaalsContact O-N 3.15Å; F62-R64 VanDerWaalsContact C-N 3.3Å; F62-R64 PolarHBondContact O-N 3.2Å; F62-L65 PolarHBondContact O-N 2.62Å; F62-R71 HydrophobicContact CD1-CG 4.43Å; F62-R71 HydrophobicContact CD2-CB 3.84Å; F62-R71 HydrophobicContact CD2-CG 3.83Å; F62-R71 HydrophobicContact CE1-CG 4.37Å; F62-R71 HydrophobicContact CE2-CB 3.57Å; F62-R71 HydrophobicContact CE2-CG 3.79Å; F62-R71 HydrophobicContact CG-CG 4.18Å; F62-R71 HydrophobicContact CZ-CB 4.17Å; F62-R71 HydrophobicContact CZ-CG 4.07Å; F62-R71 PolarHBondContact O-NE 2.82Å; F62-L74 HydrophobicContact CB-CD2 3.87Å; F62-L75 HydrophobicContact CD2-CD1 4.47Å; F62-L75 HydrophobicContact CD2-CG 4.48Å; F62-L75 HydrophobicContact CE2-CD1 4.12Å; F62-K96 HydrophobicContact CE1-CG 4.43Å; F62-F97 HydrophobicContact CD1-CE1 4.22Å; F62-F97 HydrophobicContact CD2-CD1 4.27Å; F62-F97 AromaticContact CD2-CE1 3.88Å; F62-F97 HydrophobicContact CD2-CE1 3.88Å; F62-F97 HydrophobicContact CE1-CE1 4.13Å; F62-F97 AromaticContact CE2-CD1 3.75Å; F62-F97 HydrophobicContact CE2-CD1 3.75Å; F62-F97 AromaticContact CE2-CE1 3.75Å; F62-F97 HydrophobicContact CE2-CE1 3.75Å; F62-F97 HydrophobicContact CG-CE1 4.1Å; F62-F97 AromaticContact CZ-CD1 3.95Å; F62-F97 HydrophobicContact CZ-CD1 3.95Å; F62-F97 AromaticContact CZ-CE1 3.87Å; F62-F97 HydrophobicContact CZ-CE1 3.87Å; F62-I100 HydrophobicContact CE2-CG1 4.03Å; F62-I100 HydrophobicContact CE2-CG2 4.36Å; F62-I100 HydrophobicContact CZ-CD1 4.41Å; F62-I100 HydrophobicContact CZ-CG1 3.88Å
63E98Very high98.3Very high110 Ų11065.8 Ų65.851%0.51432%0.315SS..Hα-helixtrans-72.1-22.7-178.8-70.7173.2170.700113.5V59 N61 L65 K96V59-E63 HydrophobicContact CG1-CG 4.27Å; V59-E63 WeakPolarHBondContact CG1-OE1 3.45Å; V59-E63 WeakPolarHBondContact O-CG 3.43Å; V59-E63 PolarHBondContact O-N 2.67Å; N61-E63 VanDerWaalsContact C-N 3.33Å; N61-E63 PolarHBondContact O-N 2.93Å; E63-L65 VanDerWaalsContact C-N 3.35Å; E63-K96 IonicContact OE1-NZ 3.86Å; E63-K96 PolarHBondContact OE1-NZ 3.46Å
64R97.9Very high98.3Very high193 Ų19363.9 Ų63.973%0.72831%0.306SS*.Hα-helixtrans-78.6-19.6175.9-73.9174.467.3-177.72.3113.3K60 N61 F62K60-R64 WeakPolarHBondContact O-CD 3.34Å; K60-R64 WeakPolarHBondContact O-CG 3.38Å; N61-R64 PolarHBondContact O-N 3.41Å; F62-R64 VanDerWaalsContact C-N 3.3Å; F62-R64 PolarHBondContact O-N 3.2Å
65L98.3Very high98.2Very high52 Ų5263.6 Ų63.627%0.27230%0.304SS..  trans-74.2147.3179.4-63.1173.4000110.6N61 F62 E63 D70 R71 L74N61-L65 WeakPolarHBondContact O-CG 3.44Å; N61-L65 PolarHBondContact O-N 2.89Å; F62-L65 PolarHBondContact O-N 2.62Å; E63-L65 VanDerWaalsContact C-N 3.35Å; L65-D70 HydrophobicContact CB-CB 4.2Å; L65-D70 HydrophobicContact CD1-CB 4.06Å; L65-D70 HydrophobicContact CD2-CB 4.11Å; L65-D70 HydrophobicContact CG-CB 4.34Å; L65-R71 HydrophobicContact CB-CG 3.91Å; L65-R71 HydrophobicContact CD1-CB 4.46Å; L65-R71 HydrophobicContact CD1-CG 3.94Å; L65-R71 PolarHBondContact O-NH2 2.82Å; L65-L74 HydrophobicContact CD1-CB 3.9Å; L65-L74 HydrophobicContact CD1-CD2 3.8Å; L65-L74 HydrophobicContact CD1-CG 4.43Å
66N97.6Very high98.2Very high158 Ų15863.7 Ų63.785%0.84530%0.303SS*.SBendtrans-99.9-9.6-172.4-59.9101.9000113.9
67S97.9Very high98.2Very high41 Ų4162 Ų6229%0.28730%0.295SS..SBendtrans-133.6151.5178.380.80000111.9F69 D70 R71S67-F69 PolarHBondContact O-N 3.4Å; S67-D70 PolarHBondContact O-N 3.44Å; S67-D70 PolarHBondContact OG-N 2.94Å; S67-D70 PolarHBondContact OG-OD2 3.28Å; S67-R71 WeakPolarHBondContact O-CG 3.45Å; S67-R71 PolarHBondContact O-N 3.15Å
68D96.8Very high98.2Very high75 Ų7556.2 Ų56.240%0.40127%0.273SS..Hα-helixtrans-67.6-27173.8-71.5-20.5000112.4R71 Y72 I100 T105D68-R71 WeakPolarHBondContact O-CB 3.47Å; D68-R71 PolarHBondContact O-N 3.49Å; D68-R71 IonicContact OD1-CZ 3.25Å; D68-R71 IonicContact OD1-NH1 3.91Å; D68-R71 PolarHBondContact OD1-NH1 2.91Å; D68-Y72 PolarHBondContact O-N 3.2Å; D68-I100 HydrophobicContact CB-CD1 3.77Å; D68-I100 WeakPolarHBondContact OD1-CD1 3.36Å; D68-T105 HydrophobicContact CB-CG2 4.13Å; D68-T105 WeakPolarHBondContact O-CG2 3.49Å
69F97.2Very high98.2Very high36 Ų3655.9 Ų55.916%0.15827%0.271CS..Hα-helixtrans-66.4-44.2174.6-175.7-120.2000112S67 R71 Y72 L73 L108 A109 Q112 V116S67-F69 PolarHBondContact O-N 3.4Å; F69-R71 VanDerWaalsContact C-N 3.27Å; F69-R71 PolarHBondContact O-N 2.82Å; F69-Y72 WeakPolarHBondContact O-CB 3.35Å; F69-Y72 PolarHBondContact O-N 3.17Å; F69-Y72 VanDerWaalsContact O-N 3.17Å; F69-L73 HydrophobicContact CD1-CD1 4.35Å; F69-L73 HydrophobicContact CE1-CD1 4Å; F69-L73 HydrophobicContact CZ-CD1 4.27Å; F69-L73 HydrophobicContact CZ-CD2 4.39Å; F69-L73 HydrophobicContact CZ-CG 4.45Å; F69-L73 WeakPolarHBondContact O-CG 3.47Å; F69-L73 PolarHBondContact O-N 2.68Å; F69-L108 HydrophobicContact CB-CD2 4.11Å; F69-L108 HydrophobicContact CD2-CG 4.44Å; F69-A109 HydrophobicContact CD2-CB 4.34Å; F69-A109 HydrophobicContact CE2-CB 3.97Å; F69-Q112 HydrophobicContact CE2-CB 4.18Å; F69-Q112 HydrophobicContact CZ-CB 3.74Å; F69-Q112 HydrophobicContact CZ-CG 4.27Å; F69-V116 HydrophobicContact CE1-CG1 3.84Å; F69-V116 HydrophobicContact CE2-CG2 4.43Å; F69-V116 HydrophobicContact CZ-CB 4.24Å; F69-V116 HydrophobicContact CZ-CG1 3.52Å; F69-V116 HydrophobicContact CZ-CG2 3.89Å
70D98.1Very high98.1Very high69 Ų6955.7 Ų55.737%0.36927%0.269SS..Hα-helixtrans-63.2-37.6174.1-63.6-47.2000111.3L65 S67 Y72 L73 L74L65-D70 HydrophobicContact CB-CB 4.2Å; L65-D70 HydrophobicContact CD1-CB 4.06Å; L65-D70 HydrophobicContact CD2-CB 4.11Å; L65-D70 HydrophobicContact CG-CB 4.34Å; S67-D70 PolarHBondContact O-N 3.44Å; S67-D70 PolarHBondContact OG-N 2.94Å; S67-D70 PolarHBondContact OG-OD2 3.28Å; D70-Y72 VanDerWaalsContact C-N 3.33Å; D70-L73 PolarHBondContact O-N 3.21Å; D70-L74 PolarHBondContact O-N 3.25Å
71R98.6Very high98.1Very high53 Ų5354 Ų5420%0.226%0.26CS..Hα-helixtrans-63.7-39.4175-70.4168.6-175137.93.9111.5F62 L65 S67 D68 F69 L74 L75 I100F62-R71 HydrophobicContact CD1-CG 4.43Å; F62-R71 HydrophobicContact CD2-CB 3.84Å; F62-R71 HydrophobicContact CD2-CG 3.83Å; F62-R71 HydrophobicContact CE1-CG 4.37Å; F62-R71 HydrophobicContact CE2-CB 3.57Å; F62-R71 HydrophobicContact CE2-CG 3.79Å; F62-R71 HydrophobicContact CG-CG 4.18Å; F62-R71 HydrophobicContact CZ-CB 4.17Å; F62-R71 HydrophobicContact CZ-CG 4.07Å; F62-R71 PolarHBondContact O-NE 2.82Å; L65-R71 HydrophobicContact CB-CG 3.91Å; L65-R71 HydrophobicContact CD1-CB 4.46Å; L65-R71 HydrophobicContact CD1-CG 3.94Å; L65-R71 PolarHBondContact O-NH2 2.82Å; S67-R71 WeakPolarHBondContact O-CG 3.45Å; S67-R71 PolarHBondContact O-N 3.15Å; D68-R71 WeakPolarHBondContact O-CB 3.47Å; D68-R71 PolarHBondContact O-N 3.49Å; D68-R71 IonicContact OD1-CZ 3.25Å; D68-R71 IonicContact OD1-NH1 3.91Å; D68-R71 PolarHBondContact OD1-NH1 2.91Å; F69-R71 VanDerWaalsContact C-N 3.27Å; F69-R71 PolarHBondContact O-N 2.82Å; R71-L74 PolarHBondContact O-N 2.81Å; R71-L75 WeakPolarHBondContact O-CG 3.12Å; R71-L75 PolarHBondContact O-N 2.77Å; R71-L75 VanDerWaalsContact O-N 3.07Å; R71-I100 HydrophobicContact CB-CG2 3.93Å
72Y98.3Very high98.1Very high11 Ų1150.6 Ų50.64%0.04324%0.241CC..Hα-helixtrans-59.6-50.4171.9169.7-90.9000111D68 F69 D70 L74 L75 M76 I100 T105 V106 A109D68-Y72 PolarHBondContact O-N 3.2Å; F69-Y72 WeakPolarHBondContact O-CB 3.35Å; F69-Y72 PolarHBondContact O-N 3.17Å; F69-Y72 VanDerWaalsContact O-N 3.17Å; D70-Y72 VanDerWaalsContact C-N 3.33Å; Y72-L74 VanDerWaalsContact C-N 3.32Å; Y72-L74 PolarHBondContact O-N 2.93Å; Y72-L75 PolarHBondContact O-N 3.45Å; Y72-L75 VanDerWaalsContact O-N 3.09Å; Y72-M76 HydrophobicContact CD1-CG 4.07Å; Y72-M76 HydrophobicContact CD2-CE 4.47Å; Y72-M76 HydrophobicContact CD2-CG 4.25Å; Y72-M76 HydrophobicContact CE1-CG 3.61Å; Y72-M76 HydrophobicContact CE2-CE 4.16Å; Y72-M76 HydrophobicContact CE2-CG 3.85Å; Y72-M76 HydrophobicContact CE2-SD 3.91Å; Y72-M76 HydrophobicContact CG-CG 4.37Å; Y72-M76 WeakPolarHBondContact O-CG 3.42Å; Y72-M76 PolarHBondContact O-N 3.2Å; Y72-I100 VanDerWaalsContact CD2-O 3.32Å; Y72-I100 WeakPolarHBondContact CD2-O 3.4Å; Y72-T105 HydrophobicContact CG-CG2 4.45Å; Y72-V106 HydrophobicContact CE2-CG2 4.36Å; Y72-A109 HydrophobicContact CD1-CB 3.64Å; Y72-A109 HydrophobicContact CD2-CB 4.36Å; Y72-A109 HydrophobicContact CE1-CB 3.32Å; Y72-A109 HydrophobicContact CE2-CB 4.07Å; Y72-A109 HydrophobicContact CG-CB 4.15Å
73L98Very high98.1Very high24 Ų2450.2 Ų50.213%0.12624%0.239CC..Hα-helixtrans-59-42.3178.6-64.3177.2000112F69 D70 L75 M76 D77 V116F69-L73 HydrophobicContact CD1-CD1 4.35Å; F69-L73 HydrophobicContact CE1-CD1 4Å; F69-L73 HydrophobicContact CZ-CD1 4.27Å; F69-L73 HydrophobicContact CZ-CD2 4.39Å; F69-L73 HydrophobicContact CZ-CG 4.45Å; F69-L73 WeakPolarHBondContact O-CG 3.47Å; F69-L73 PolarHBondContact O-N 2.68Å; D70-L73 PolarHBondContact O-N 3.21Å; L73-L75 VanDerWaalsContact C-N 3.33Å; L73-L75 PolarHBondContact O-N 3.16Å; L73-M76 PolarHBondContact O-N 3.22Å; L73-D77 WeakPolarHBondContact O-CB 3.38Å; L73-D77 PolarHBondContact O-N 2.85Å; L73-V116 HydrophobicContact CD1-CG1 4.47Å; L73-V116 HydrophobicContact CD2-CB 4.08Å; L73-V116 HydrophobicContact CD2-CG2 4.01Å
74L98.6Very high98.2Very high39 Ų3945.6 Ų45.620%0.20422%0.217CC..Hα-helixtrans-57.6-44.2174.5173.869.5000112.2N61 F62 L65 D70 R71 Y72 L78N61-L74 HydrophobicContact CB-CD1 4.48Å; N61-L74 HydrophobicContact CB-CD2 4.15Å; F62-L74 HydrophobicContact CB-CD2 3.87Å; L65-L74 HydrophobicContact CD1-CB 3.9Å; L65-L74 HydrophobicContact CD1-CD2 3.8Å; L65-L74 HydrophobicContact CD1-CG 4.43Å; D70-L74 PolarHBondContact O-N 3.25Å; R71-L74 PolarHBondContact O-N 2.81Å; Y72-L74 VanDerWaalsContact C-N 3.32Å; Y72-L74 PolarHBondContact O-N 2.93Å; L74-L78 WeakPolarHBondContact O-CB 3.31Å; L74-L78 PolarHBondContact O-N 2.86Å; L74-L78 VanDerWaalsContact O-N 3.07Å
75L98.6Very high98.2Very high0 Ų036.6 Ų36.60%018%0.184CC..Hα-helixtrans-72.5-36.3-178.8-69.6-178.1000112F62 R71 Y72 L73 L78 Q79 F86 V89 F97 I100 V101F62-L75 HydrophobicContact CD2-CD1 4.47Å; F62-L75 HydrophobicContact CD2-CG 4.48Å; F62-L75 HydrophobicContact CE2-CD1 4.12Å; R71-L75 WeakPolarHBondContact O-CG 3.12Å; R71-L75 PolarHBondContact O-N 2.77Å; R71-L75 VanDerWaalsContact O-N 3.07Å; Y72-L75 PolarHBondContact O-N 3.45Å; Y72-L75 VanDerWaalsContact O-N 3.09Å; L73-L75 VanDerWaalsContact C-N 3.33Å; L73-L75 PolarHBondContact O-N 3.16Å; L75-L78 HydrophobicContact CD2-CD2 4.46Å; L75-L78 WeakPolarHBondContact O-CB 3.17Å; L75-L78 PolarHBondContact O-N 3.11Å; L75-Q79 PolarHBondContact O-N 3.21Å; L75-F86 HydrophobicContact CB-CE2 4.18Å; L75-F86 VanDerWaalsContact O-CD2 3.27Å; L75-F86 WeakPolarHBondContact O-CD2 3.41Å; L75-F86 WeakPolarHBondContact O-CE2 3.44Å; L75-V89 HydrophobicContact CD2-CG1 4.2Å; L75-F97 HydrophobicContact CD1-CD1 4.16Å; L75-I100 HydrophobicContact CD1-CB 4.19Å; L75-I100 HydrophobicContact CD1-CG2 3.82Å; L75-V101 HydrophobicContact CB-CG1 4.2Å; L75-V101 HydrophobicContact CD1-CG1 3.59Å
76M98.1Very high98.2Very high22 Ų2234.1 Ų34.111%0.10817%0.171CC..Hα-helixtrans-65.9-43.7173.2-64.7-57.59700111.4Y72 L73 L78 Q79 D80 F86 V101 V171Y72-M76 HydrophobicContact CD1-CG 4.07Å; Y72-M76 HydrophobicContact CD2-CE 4.47Å; Y72-M76 HydrophobicContact CD2-CG 4.25Å; Y72-M76 HydrophobicContact CE1-CG 3.61Å; Y72-M76 HydrophobicContact CE2-CE 4.16Å; Y72-M76 HydrophobicContact CE2-CG 3.85Å; Y72-M76 HydrophobicContact CE2-SD 3.91Å; Y72-M76 HydrophobicContact CG-CG 4.37Å; Y72-M76 WeakPolarHBondContact O-CG 3.42Å; Y72-M76 PolarHBondContact O-N 3.2Å; L73-M76 PolarHBondContact O-N 3.22Å; M76-L78 PolarHBondContact O-N 2.74Å; M76-Q79 WeakPolarHBondContact O-CB 3.47Å; M76-Q79 PolarHBondContact O-N 3.34Å; M76-Q79 VanDerWaalsContact O-N 3.12Å; M76-D80 PolarHBondContact O-N 3.33Å; M76-F86 HydrophobicContact CE-CE2 4.1Å; M76-F86 HydrophobicContact CE-CZ 4.2Å; M76-V101 HydrophobicContact CE-CB 4.44Å; M76-V101 HydrophobicContact CE-CG1 4.16Å; M76-V171 HydrophobicContact SD-CG1 4.37Å
77D98.3Very high98.3Very high53 Ų5326.8 Ų26.828%0.28313%0.131SC..Hα-helixtrans-60.8-31.5174.2-77.4-24.3000112.1L73 R81 R118L73-D77 WeakPolarHBondContact O-CB 3.38Å; L73-D77 PolarHBondContact O-N 2.85Å; D77-R81 WeakPolarHBondContact O-CB 3.47Å; D77-R81 PolarHBondContact O-N 3.44Å; D77-R81 PolarHBondContact O-NH1 3.28Å; D77-R118 IonicContact OD1-NH1 3.59Å; D77-R118 IonicContact OD2-NH1 3.01Å; D77-R118 PolarHBondContact OD2-NH1 2.9Å
78L98.7Very high98.4Very high1 Ų126.9 Ų26.91%0.00513%0.127CC..Hα-helixtrans-71.9-43.8173.8174.463.1000111.7V58 L74 L75 M76 D80 R81 N82 L85 F86 V89V58-L78 HydrophobicContact CG1-CD2 3.82Å; V58-L78 HydrophobicContact CG2-CD1 4.33Å; V58-L78 HydrophobicContact CG2-CD2 3.97Å; L74-L78 WeakPolarHBondContact O-CB 3.31Å; L74-L78 PolarHBondContact O-N 2.86Å; L74-L78 VanDerWaalsContact O-N 3.07Å; L75-L78 HydrophobicContact CD2-CD2 4.46Å; L75-L78 WeakPolarHBondContact O-CB 3.17Å; L75-L78 PolarHBondContact O-N 3.11Å; M76-L78 PolarHBondContact O-N 2.74Å; L78-D80 PolarHBondContact O-N 2.79Å; L78-R81 PolarHBondContact O-N 2.92Å; L78-N82 HydrophobicContact CD1-CB 4.46Å; L78-N82 PolarHBondContact O-N 3.48Å; L78-L85 HydrophobicContact CD1-CB 4.23Å; L78-L85 HydrophobicContact CD1-CD2 3.74Å; L78-L85 HydrophobicContact CD1-CG 3.9Å; L78-F86 HydrophobicContact CD2-CB 4.34Å; L78-F86 HydrophobicContact CD2-CD2 4.47Å; L78-F86 HydrophobicContact CG-CB 3.98Å; L78-F86 HydrophobicContact CG-CD2 4.4Å; L78-V89 HydrophobicContact CD2-CB 4.39Å; L78-V89 HydrophobicContact CD2-CG2 4.06Å
79Q98.5Very high98.4Very high3 Ų323.3 Ų23.31%0.01411%0.108CC..Hα-helixtrans-55.6-43175.6-167.7-179.735.500111.2P22 L75 M76 R81 F86 R121P22-Q79 WeakPolarHBondContact CB-O 3.48Å; L75-Q79 PolarHBondContact O-N 3.21Å; M76-Q79 WeakPolarHBondContact O-CB 3.47Å; M76-Q79 PolarHBondContact O-N 3.34Å; M76-Q79 VanDerWaalsContact O-N 3.12Å; Q79-R81 PolarHBondContact O-N 3.44Å; Q79-F86 HydrophobicContact CB-CB 4.37Å; Q79-F86 HydrophobicContact CB-CD1 4.09Å; Q79-F86 HydrophobicContact CB-CD2 3.71Å; Q79-F86 HydrophobicContact CB-CE1 4.28Å; Q79-F86 HydrophobicContact CB-CE2 3.92Å; Q79-F86 HydrophobicContact CB-CG 3.79Å; Q79-F86 HydrophobicContact CB-CZ 4.2Å; Q79-F86 HydrophobicContact CG-CD1 3.81Å; Q79-F86 HydrophobicContact CG-CD2 4.35Å; Q79-F86 HydrophobicContact CG-CE1 3.91Å; Q79-F86 HydrophobicContact CG-CE2 4.44Å; Q79-F86 HydrophobicContact CG-CG 4.04Å; Q79-F86 HydrophobicContact CG-CZ 4.23Å; Q79-R121 VanDerWaalsContact CD-NH2 3.27Å; Q79-R121 VanDerWaalsContact NE2-NH2 3.15Å
80D97.6Very high98.5Very high22 Ų2221.8 Ų21.812%0.11810%0.101CC..THydrogen-bonded Turntrans-81.15.2179.5-71.3-19.2000115M76 L78 K119 R121M76-D80 PolarHBondContact O-N 3.33Å; L78-D80 PolarHBondContact O-N 2.79Å; D80-K119 HydrophobicContact CB-CD 3.54Å; D80-K119 PolarHBondContact O-NZ 3.03Å; D80-K119 VanDerWaalsContact OD2-CB 3.27Å; D80-K119 WeakPolarHBondContact OD2-CB 3.42Å; D80-K119 WeakPolarHBondContact OD2-CD 3.32Å; D80-R121 WeakPolarHBondContact OD1-CD 3.36Å; D80-R121 IonicContact OD1-CZ 2.64Å; D80-R121 IonicContact OD1-NE 3.2Å; D80-R121 IonicContact OD1-NH1 3.31Å
81R98.5Very high98.5Very high90 Ų9020.6 Ų20.634%0.3410%0.097SC..THydrogen-bonded Turntrans-117.5-45.7177.9-179178.365.2-110.64.3111.8N25 D27 D77 L78 Q79N25-R81 WeakPolarHBondContact CB-O 3.22Å; N25-R81 PolarHBondContact ND2-O 2.98Å; D27-R81 IonicContact OD2-NE 3.86Å; D77-R81 WeakPolarHBondContact O-CB 3.47Å; D77-R81 PolarHBondContact O-N 3.44Å; D77-R81 PolarHBondContact O-NH1 3.28Å; L78-R81 PolarHBondContact O-N 2.92Å; Q79-R81 PolarHBondContact O-N 3.44Å
82N98.8Very high98.5Very high0 Ų021.4 Ų21.40%011%0.11CC..  trans-153.796.6-172.8-176.6-25.2000109.4N25 D27 L78 L85 F86 Y549N25-N82 VanDerWaalsContact O-CG 3.3Å; N25-N82 PolarHBondContact O-OD1 3.39Å; D27-N82 WeakPolarHBondContact OD2-CB 3.13Å; D27-N82 PolarHBondContact OD2-ND2 3.44Å; L78-N82 HydrophobicContact CD1-CB 4.46Å; L78-N82 PolarHBondContact O-N 3.48Å; N82-L85 HydrophobicContact CB-CB 4.03Å; N82-L85 PolarHBondContact O-N 2.94Å; N82-L85 VanDerWaalsContact OD1-CB 3.29Å; N82-L85 WeakPolarHBondContact OD1-CB 3.33Å; N82-L85 PolarHBondContact OD1-N 2.93Å; N82-F86 PolarHBondContact O-N 3.04Å; N82-Y549 PolarHBondContact ND2-OH 2.91Å; N82-Y549 PolarHBondContact OD1-OH 3.22Å
83E98.8Very high98.4Very high2 Ų224.2 Ų24.21%0.00913%0.126CC..Hα-helixtrans-65.7-41.1-172-176.9173.7-105.600112.3P22 H23 F86 Y87 P185P22-E83 VanDerWaalsContact O-CB 3.31Å; P22-E83 WeakPolarHBondContact O-CB 3.32Å; P22-E83 PolarHBondContact O-N 3.42Å; H23-E83 IonicContact CE1-OE1 2.69Å; H23-E83 PolarHBondContact CE1-OE1 3.45Å; H23-E83 IonicContact CE1-OE2 2.96Å; H23-E83 IonicContact CG-OE2 3.2Å; H23-E83 IonicContact ND1-OE1 2.63Å; H23-E83 PolarHBondContact ND1-OE1 2.87Å; H23-E83 IonicContact ND1-OE2 3.03Å; H23-E83 PolarHBondContact ND1-OE2 3.33Å; E83-F86 WeakPolarHBondContact O-CB 3.37Å; E83-F86 PolarHBondContact O-N 2.96Å; E83-Y87 HydrophobicContact CG-CD2 3.86Å; E83-Y87 HydrophobicContact CG-CE2 3.61Å; E83-Y87 WeakPolarHBondContact O-CD2 3.48Å; E83-Y87 PolarHBondContact O-N 3.03Å; E83-Y87 VanDerWaalsContact O-N 3.09Å; E83-P185 HydrophobicContact CG-CB 4.46Å; E83-P185 HydrophobicContact CG-CG 3.97Å; E83-P185 WeakPolarHBondContact OE1-CB 3.49Å; E83-P185 WeakPolarHBondContact OE2-CG 3.2Å
84K98.7Very high98.3Very high13 Ų1323.8 Ų23.86%0.05712%0.124CC..Hα-helixtrans-62.3-46.1177.1-73.9-85.1-179.8163.40111Y87 K88 Y545 S546 T547 D548 Y549 D550K84-Y87 PolarHBondContact O-N 3.33Å; K84-K88 WeakPolarHBondContact O-CB 3.46Å; K84-K88 PolarHBondContact O-N 3.07Å; K84-Y545 HydrophobicContact CD-CE2 4.45Å; K84-Y545 WeakPolarHBondContact CD-OH 3.44Å; K84-Y545 WeakPolarHBondContact CE-OH 3.38Å; K84-Y545 WeakPolarHBondContact CG-OH 3.45Å; K84-S546 PolarHBondContact NZ-O 3.41Å; K84-T547 WeakPolarHBondContact CD-O 3.45Å; K84-D548 VanDerWaalsContact CD-O 3.26Å; K84-D548 WeakPolarHBondContact CD-O 3.49Å; K84-D548 WeakPolarHBondContact CE-O 3.39Å; K84-D548 PolarHBondContact NZ-O 3.19Å; K84-Y549 HydrophobicContact CB-CD1 3.65Å; K84-Y549 HydrophobicContact CB-CE1 3.55Å; K84-Y549 HydrophobicContact CG-CD1 3.98Å; K84-Y549 HydrophobicContact CG-CE1 4.32Å; K84-D550 WeakPolarHBondContact CE-OD2 3.25Å; K84-D550 VanDerWaalsContact NZ-CG 3.28Å; K84-D550 IonicContact NZ-OD1 3.76Å; K84-D550 PolarHBondContact NZ-OD1 3.22Å; K84-D550 IonicContact NZ-OD2 3.81Å; K84-D550 PolarHBondContact NZ-OD2 3.33Å
85L98.9Very high98Very high4 Ų427.1 Ų27.12%0.02114%0.139CC..Hα-helixtrans-66.5-39.8177.1-177.960000112.4Q51 Q54 V55 V58 L78 N82 Y87 K88 V89Q51-L85 HydrophobicContact CG-CD1 4.24Å; Q54-L85 HydrophobicContact CB-CD1 3.55Å; Q54-L85 HydrophobicContact CB-CD2 3.73Å; Q54-L85 HydrophobicContact CB-CG 4.3Å; Q54-L85 HydrophobicContact CG-CD2 4.46Å; V55-L85 HydrophobicContact CG2-CD1 3.84Å; V58-L85 HydrophobicContact CG2-CD2 4.21Å; L78-L85 HydrophobicContact CD1-CB 4.23Å; L78-L85 HydrophobicContact CD1-CD2 3.74Å; L78-L85 HydrophobicContact CD1-CG 3.9Å; N82-L85 HydrophobicContact CB-CB 4.03Å; N82-L85 PolarHBondContact O-N 2.94Å; N82-L85 VanDerWaalsContact OD1-CB 3.29Å; N82-L85 WeakPolarHBondContact OD1-CB 3.33Å; N82-L85 PolarHBondContact OD1-N 2.93Å; L85-Y87 PolarHBondContact O-N 2.88Å; L85-K88 PolarHBondContact O-N 3.26Å; L85-V89 HydrophobicContact CD1-CG2 4.27Å; L85-V89 WeakPolarHBondContact O-CG2 3.44Å; L85-V89 PolarHBondContact O-N 3.14Å
86F98.9Very high97.8Very high0 Ų030.5 Ų30.50%015%0.154CC..Hα-helixtrans-53.1-55.1173.4172.1-104.9000111.1L75 M76 L78 Q79 N82 E83 K88 V89 L90 V101 A175L75-F86 HydrophobicContact CB-CE2 4.18Å; L75-F86 VanDerWaalsContact O-CD2 3.27Å; L75-F86 WeakPolarHBondContact O-CD2 3.41Å; L75-F86 WeakPolarHBondContact O-CE2 3.44Å; M76-F86 HydrophobicContact CE-CE2 4.1Å; M76-F86 HydrophobicContact CE-CZ 4.2Å; L78-F86 HydrophobicContact CD2-CB 4.34Å; L78-F86 HydrophobicContact CD2-CD2 4.47Å; L78-F86 HydrophobicContact CG-CB 3.98Å; L78-F86 HydrophobicContact CG-CD2 4.4Å; Q79-F86 HydrophobicContact CB-CB 4.37Å; Q79-F86 HydrophobicContact CB-CD1 4.09Å; Q79-F86 HydrophobicContact CB-CD2 3.71Å; Q79-F86 HydrophobicContact CB-CE1 4.28Å; Q79-F86 HydrophobicContact CB-CE2 3.92Å; Q79-F86 HydrophobicContact CB-CG 3.79Å; Q79-F86 HydrophobicContact CB-CZ 4.2Å; Q79-F86 HydrophobicContact CG-CD1 3.81Å; Q79-F86 HydrophobicContact CG-CD2 4.35Å; Q79-F86 HydrophobicContact CG-CE1 3.91Å; Q79-F86 HydrophobicContact CG-CE2 4.44Å; Q79-F86 HydrophobicContact CG-CG 4.04Å; Q79-F86 HydrophobicContact CG-CZ 4.23Å; N82-F86 PolarHBondContact O-N 3.04Å; E83-F86 WeakPolarHBondContact O-CB 3.37Å; E83-F86 PolarHBondContact O-N 2.96Å; F86-K88 VanDerWaalsContact C-N 3.34Å; F86-K88 PolarHBondContact O-N 3.17Å; F86-V89 PolarHBondContact O-N 2.84Å; F86-L90 HydrophobicContact CD1-CD2 4.45Å; F86-L90 HydrophobicContact CD2-CD1 3.83Å; F86-L90 HydrophobicContact CE1-CD1 4.25Å; F86-L90 HydrophobicContact CE1-CD2 3.69Å; F86-L90 HydrophobicContact CE2-CD1 3.53Å; F86-L90 HydrophobicContact CE2-CD2 4.23Å; F86-L90 HydrophobicContact CG-CD1 4.32Å; F86-L90 HydrophobicContact CZ-CD1 3.77Å; F86-L90 HydrophobicContact CZ-CD2 3.56Å; F86-L90 HydrophobicContact CZ-CG 4.34Å; F86-L90 VanDerWaalsContact O-CD1 3.29Å; F86-L90 WeakPolarHBondContact O-CD1 3.17Å; F86-L90 PolarHBondContact O-N 3.1Å; F86-V101 HydrophobicContact CE2-CG1 4.31Å; F86-V101 HydrophobicContact CZ-CG1 4.29Å; F86-A175 HydrophobicContact CE1-CB 4.16Å; F86-A175 HydrophobicContact CZ-CB 4.23Å
87Y98.8Very high97.8Very high4 Ų429.6 Ų29.62%0.01615%0.149CC..Hα-helixtrans-69.4-30.4-180-69.7-63000113.1E83 K84 L85 V89 L90 T91 A175 T178 A179 P185 Y545E83-Y87 HydrophobicContact CG-CD2 3.86Å; E83-Y87 HydrophobicContact CG-CE2 3.61Å; E83-Y87 WeakPolarHBondContact O-CD2 3.48Å; E83-Y87 PolarHBondContact O-N 3.03Å; E83-Y87 VanDerWaalsContact O-N 3.09Å; K84-Y87 PolarHBondContact O-N 3.33Å; L85-Y87 PolarHBondContact O-N 2.88Å; Y87-V89 VanDerWaalsContact C-N 3.34Å; Y87-L90 HydrophobicContact CD1-CD2 4.39Å; Y87-L90 PolarHBondContact O-N 3.33Å; Y87-T91 WeakPolarHBondContact O-CB 3.14Å; Y87-T91 WeakPolarHBondContact O-CG2 3.09Å; Y87-T91 PolarHBondContact O-N 2.86Å; Y87-T91 PolarHBondContact O-OG1 2.66Å; Y87-A175 HydrophobicContact CE1-CB 4.46Å; Y87-A175 WeakPolarHBondContact CE1-O 3.33Å; Y87-T178 HydrophobicContact CD1-CG2 3.55Å; Y87-T178 HydrophobicContact CD2-CG2 3.74Å; Y87-T178 HydrophobicContact CE1-CG2 3.44Å; Y87-T178 VanDerWaalsContact CE1-CG2 3.44Å; Y87-T178 HydrophobicContact CE2-CG2 3.63Å; Y87-T178 HydrophobicContact CG-CG2 3.7Å; Y87-T178 VanDerWaalsContact CZ-CG2 3.47Å; Y87-A179 HydrophobicContact CD1-CB 4.23Å; Y87-P185 HydrophobicContact CD2-CG 4.39Å; Y87-P185 HydrophobicContact CE2-CB 3.7Å; Y87-P185 HydrophobicContact CE2-CG 3.74Å; Y87-Y545 AromaticContact CD2-CE1 3.83Å; Y87-Y545 HydrophobicContact CD2-CE1 3.83Å; Y87-Y545 HydrophobicContact CG-CE1 4.15Å
88K98.8Very high97.7Very high44 Ų4427.2 Ų27.219%0.19114%0.136CC..Hα-helixtrans-62.3-41.4171.6-168.973.2166.4-159.40111.5Q51 V55 K84 L85 F86 T91 S92 T547 D548Q51-K88 HydrophobicContact CG-CB 4.4Å; Q51-K88 HydrophobicContact CG-CG 4.03Å; Q51-K88 VanDerWaalsContact OE1-CD 3.29Å; Q51-K88 VanDerWaalsContact OE1-CE 3.31Å; V55-K88 HydrophobicContact CG2-CB 4.26Å; V55-K88 HydrophobicContact CG2-CG 3.71Å; K84-K88 WeakPolarHBondContact O-CB 3.46Å; K84-K88 PolarHBondContact O-N 3.07Å; L85-K88 PolarHBondContact O-N 3.26Å; F86-K88 VanDerWaalsContact C-N 3.34Å; F86-K88 PolarHBondContact O-N 3.17Å; K88-T91 PolarHBondContact O-OG1 3.34Å; K88-S92 WeakPolarHBondContact O-CB 3.34Å; K88-S92 PolarHBondContact O-N 2.98Å; K88-T547 WeakPolarHBondContact CD-OG1 3.45Å; K88-D548 IonicContact NZ-OD1 3.63Å; K88-D548 PolarHBondContact NZ-OD1 3.24Å
89V98.8Very high97.4Very high0 Ų028.6 Ų28.60%015%0.145CC..Hα-helixtrans-64-52.3175.21710000110V55 V58 L75 L78 L85 F86 Y87 T91 S92 F97V55-V89 HydrophobicContact CB-CG2 4.4Å; V55-V89 HydrophobicContact CG1-CG2 4.32Å; V55-V89 HydrophobicContact CG2-CG2 3.99Å; V58-V89 HydrophobicContact CB-CG2 3.98Å; V58-V89 HydrophobicContact CG1-CG1 4.11Å; V58-V89 HydrophobicContact CG1-CG2 3.92Å; V58-V89 HydrophobicContact CG2-CG2 4.29Å; L75-V89 HydrophobicContact CD2-CG1 4.2Å; L78-V89 HydrophobicContact CD2-CB 4.39Å; L78-V89 HydrophobicContact CD2-CG2 4.06Å; L85-V89 HydrophobicContact CD1-CG2 4.27Å; L85-V89 WeakPolarHBondContact O-CG2 3.44Å; L85-V89 PolarHBondContact O-N 3.14Å; F86-V89 PolarHBondContact O-N 2.84Å; Y87-V89 VanDerWaalsContact C-N 3.34Å; V89-T91 VanDerWaalsContact C-N 3.3Å; V89-T91 PolarHBondContact O-N 2.77Å; V89-S92 WeakPolarHBondContact O-CB 3.48Å; V89-S92 PolarHBondContact O-N 3.47Å; V89-S92 VanDerWaalsContact O-N 3.09Å; V89-S92 PolarHBondContact O-OG 3.48Å; V89-F97 HydrophobicContact CG1-CD1 4.41Å; V89-F97 HydrophobicContact CG1-CD2 4.21Å; V89-F97 HydrophobicContact CG1-CE1 4.08Å; V89-F97 HydrophobicContact CG1-CE2 3.88Å; V89-F97 HydrophobicContact CG1-CG 4.49Å; V89-F97 HydrophobicContact CG1-CZ 3.82Å; V89-F97 WeakPolarHBondContact O-CD2 3.18Å; V89-F97 WeakPolarHBondContact O-CE2 3.19Å
90L98.5Very high97.4Very high3 Ų328.8 Ų28.82%0.01615%0.146CC..Hα-helixtrans-56.8-43.2179.5-91.562.9000112.4F86 Y87 S92 D93 V94 F97 V101 A179F86-L90 HydrophobicContact CD1-CD2 4.45Å; F86-L90 HydrophobicContact CD2-CD1 3.83Å; F86-L90 HydrophobicContact CE1-CD1 4.25Å; F86-L90 HydrophobicContact CE1-CD2 3.69Å; F86-L90 HydrophobicContact CE2-CD1 3.53Å; F86-L90 HydrophobicContact CE2-CD2 4.23Å; F86-L90 HydrophobicContact CG-CD1 4.32Å; F86-L90 HydrophobicContact CZ-CD1 3.77Å; F86-L90 HydrophobicContact CZ-CD2 3.56Å; F86-L90 HydrophobicContact CZ-CG 4.34Å; F86-L90 VanDerWaalsContact O-CD1 3.29Å; F86-L90 WeakPolarHBondContact O-CD1 3.17Å; F86-L90 PolarHBondContact O-N 3.1Å; Y87-L90 HydrophobicContact CD1-CD2 4.39Å; Y87-L90 PolarHBondContact O-N 3.33Å; L90-S92 VanDerWaalsContact C-N 3.32Å; L90-D93 CarbonylContact O-C 3.55Å; L90-V94 VanDerWaalsContact O-CA 3.31Å; L90-V94 WeakPolarHBondContact O-CA 3.33Å; L90-V94 PolarHBondContact O-N 2.71Å; L90-F97 HydrophobicContact CG-CB 4.27Å; L90-V101 HydrophobicContact CD1-CG1 4.13Å; L90-V101 HydrophobicContact CD2-CG1 4.24Å; L90-V101 HydrophobicContact CD2-CG2 4.01Å; L90-V101 HydrophobicContact CG-CG1 4.34Å; L90-A179 HydrophobicContact CB-CB 4.23Å; L90-A179 HydrophobicContact CD2-CB 4.05Å
91T98.1Very high97.3Very high45 Ų4527.8 Ų27.828%0.27614%0.141SC..Hα-helixtrans-79.7-12.6-178.754.60000113.7Y87 K88 V89 D93 A179 T547Y87-T91 WeakPolarHBondContact O-CB 3.14Å; Y87-T91 WeakPolarHBondContact O-CG2 3.09Å; Y87-T91 PolarHBondContact O-N 2.86Å; Y87-T91 PolarHBondContact O-OG1 2.66Å; K88-T91 PolarHBondContact O-OG1 3.34Å; V89-T91 VanDerWaalsContact C-N 3.3Å; V89-T91 PolarHBondContact O-N 2.77Å; T91-D93 VanDerWaalsContact C-N 3.33Å; T91-A179 HydrophobicContact CG2-CB 4.4Å; T91-T547 HydrophobicContact CG2-CG2 4.47Å
92S97.9Very high97.1Very high69 Ų6924.1 Ų24.148%0.48313%0.127SC..Hα-helixtrans-70.6-30.1174.670.80000112.8K88 V89 L90K88-S92 WeakPolarHBondContact O-CB 3.34Å; K88-S92 PolarHBondContact O-N 2.98Å; V89-S92 WeakPolarHBondContact O-CB 3.48Å; V89-S92 PolarHBondContact O-N 3.47Å; V89-S92 VanDerWaalsContact O-N 3.09Å; V89-S92 PolarHBondContact O-OG 3.48Å; L90-S92 VanDerWaalsContact C-N 3.32Å
93D97.6Very high96.4Very high70 Ų7025.8 Ų25.837%0.37414%0.137SC..SBendtrans-155.981.8174.6-171-17000109.7L90 T91 E95 K96 F97L90-D93 CarbonylContact O-C 3.55Å; T91-D93 VanDerWaalsContact C-N 3.33Å; D93-E95 PolarHBondContact O-N 2.73Å; D93-E95 PolarHBondContact OD1-N 2.9Å; D93-K96 HydrophobicContact CB-CB 4.01Å; D93-K96 PolarHBondContact O-N 3.48Å; D93-K96 WeakPolarHBondContact OD1-CB 3.39Å; D93-K96 PolarHBondContact OD1-N 3.16Å; D93-K96 VanDerWaalsContact OD1-N 3.08Å; D93-K96 WeakPolarHBondContact OD2-CB 3.41Å; D93-F97 HydrophobicContact CB-CD2 4.14Å; D93-F97 HydrophobicContact CB-CE2 3.9Å; D93-F97 WeakPolarHBondContact O-CD2 3.43Å; D93-F97 PolarHBondContact O-N 3.07Å
94V95Very high96Very high16 Ų1628.2 Ų28.210%0.09715%0.153CC..Hα-helixtrans-63-32.4-174.967.50000112.3L90 M98 L503 I506L90-V94 VanDerWaalsContact O-CA 3.31Å; L90-V94 WeakPolarHBondContact O-CA 3.33Å; L90-V94 PolarHBondContact O-N 2.71Å; V94-M98 HydrophobicContact CG2-CB 4.24Å; V94-M98 WeakPolarHBondContact O-CB 3.41Å; V94-M98 PolarHBondContact O-N 3.38Å; V94-L503 HydrophobicContact CG1-CB 4.49Å; V94-L503 VanDerWaalsContact CG1-O 3.31Å; V94-L503 WeakPolarHBondContact CG1-O 3.37Å; V94-I506 HydrophobicContact CG1-CG2 4.34Å; V94-I506 HydrophobicContact CG2-CG2 4.23Å
95E92.4Very high95.8Very high108 Ų10828 Ų2851%0.50515%0.153SC..Hα-helixtrans-68.2-37.1179.6-171.4166.6-176.100111.3D93 P99 L503D93-E95 PolarHBondContact O-N 2.73Å; D93-E95 PolarHBondContact OD1-N 2.9Å; E95-P99 WeakPolarHBondContact O-CD 3.27Å; E95-P99 WeakPolarHBondContact O-CG 3.43Å; E95-L503 HydrophobicContact CB-CB 4.46Å; E95-L503 HydrophobicContact CG-CD1 4.17Å
96K95.2Very high95.6Very high72 Ų7227.9 Ų27.931%0.31315%0.153SC..Hα-helixtrans-73.3-40.7174.9-174.4175.2-177.5174.90113.5F62 E63 D93F62-K96 HydrophobicContact CE1-CG 4.43Å; E63-K96 IonicContact OE1-NZ 3.86Å; E63-K96 PolarHBondContact OE1-NZ 3.46Å; D93-K96 HydrophobicContact CB-CB 4.01Å; D93-K96 PolarHBondContact O-N 3.48Å; D93-K96 WeakPolarHBondContact OD1-CB 3.39Å; D93-K96 PolarHBondContact OD1-N 3.16Å; D93-K96 VanDerWaalsContact OD1-N 3.08Å; D93-K96 WeakPolarHBondContact OD2-CB 3.41Å
97F97.5Very high95.2Very high2 Ų228.3 Ų28.31%0.00916%0.157CC..Hα-helixtrans-94.8-28-170.9-61.8-60.6000114.7V59 F62 L75 V89 L90 D93 I100 V101V59-F97 HydrophobicContact CG2-CZ 4.09Å; F62-F97 HydrophobicContact CD1-CE1 4.22Å; F62-F97 HydrophobicContact CD2-CD1 4.27Å; F62-F97 AromaticContact CD2-CE1 3.88Å; F62-F97 HydrophobicContact CD2-CE1 3.88Å; F62-F97 HydrophobicContact CE1-CE1 4.13Å; F62-F97 AromaticContact CE2-CD1 3.75Å; F62-F97 HydrophobicContact CE2-CD1 3.75Å; F62-F97 AromaticContact CE2-CE1 3.75Å; F62-F97 HydrophobicContact CE2-CE1 3.75Å; F62-F97 HydrophobicContact CG-CE1 4.1Å; F62-F97 AromaticContact CZ-CD1 3.95Å; F62-F97 HydrophobicContact CZ-CD1 3.95Å; F62-F97 AromaticContact CZ-CE1 3.87Å; F62-F97 HydrophobicContact CZ-CE1 3.87Å; L75-F97 HydrophobicContact CD1-CD1 4.16Å; V89-F97 HydrophobicContact CG1-CD1 4.41Å; V89-F97 HydrophobicContact CG1-CD2 4.21Å; V89-F97 HydrophobicContact CG1-CE1 4.08Å; V89-F97 HydrophobicContact CG1-CE2 3.88Å; V89-F97 HydrophobicContact CG1-CG 4.49Å; V89-F97 HydrophobicContact CG1-CZ 3.82Å; V89-F97 WeakPolarHBondContact O-CD2 3.18Å; V89-F97 WeakPolarHBondContact O-CE2 3.19Å; L90-F97 HydrophobicContact CG-CB 4.27Å; D93-F97 HydrophobicContact CB-CD2 4.14Å; D93-F97 HydrophobicContact CB-CE2 3.9Å; D93-F97 WeakPolarHBondContact O-CD2 3.43Å; D93-F97 PolarHBondContact O-N 3.07Å; F97-I100 WeakPolarHBondContact O-CB 3.33Å; F97-I100 PolarHBondContact O-N 3.48Å; F97-I100 VanDerWaalsContact O-N 3.08Å; F97-V101 PolarHBondContact O-N 3.45Å; F97-V101 VanDerWaalsContact O-N 3.12Å
98M95.1Very high95Very high4 Ų432 Ų322%0.0218%0.176CC..Hα-helixtrans-57-44.4179.5-179.5-177.177.500112.8V94 I100 V101 Y102 L176 L503V94-M98 HydrophobicContact CG2-CB 4.24Å; V94-M98 WeakPolarHBondContact O-CB 3.41Å; V94-M98 PolarHBondContact O-N 3.38Å; M98-I100 PolarHBondContact O-N 2.85Å; M98-I100 VanDerWaalsContact O-N 3.16Å; M98-V101 PolarHBondContact O-N 3.24Å; M98-Y102 PolarHBondContact O-N 2.96Å; M98-L176 HydrophobicContact CB-CD2 4.44Å; M98-L176 HydrophobicContact CG-CD1 4Å; M98-L176 HydrophobicContact CG-CD2 3.85Å; M98-L176 HydrophobicContact SD-CD1 4.41Å; M98-L503 HydrophobicContact CE-CD1 3.72Å; M98-L503 HydrophobicContact CE-CD2 3.75Å; M98-L503 HydrophobicContact CE-CG 4.41Å; M98-L503 HydrophobicContact SD-CD2 4.3Å
99P93.8Very high94.8Very high30 Ų3029.9 Ų29.920%0.19517%0.167CC..Hα-helixtrans-64.8-19.5178.4-21.634.5000114.2E95 T103 P104 T105E95-P99 WeakPolarHBondContact O-CD 3.27Å; E95-P99 WeakPolarHBondContact O-CG 3.43Å; P99-T103 WeakPolarHBondContact CA-O 3.34Å; P99-P104 WeakPolarHBondContact O-CD 3.34Å; P99-T105 WeakPolarHBondContact O-CB 3.04Å; P99-T105 PolarHBondContact O-N 3.28Å; P99-T105 PolarHBondContact O-OG1 3.02Å; P99-T105 VanDerWaalsContact O-OG1 3.12Å
100I97.2Very high94.7Very high7 Ų729.9 Ų29.94%0.03617%0.167CC..Hα-helixtrans-84.8-48.3178.4-53.6-60.2000111F62 D68 R71 Y72 L75 F97 M98 Y102 T105F62-I100 HydrophobicContact CE2-CG1 4.03Å; F62-I100 HydrophobicContact CE2-CG2 4.36Å; F62-I100 HydrophobicContact CZ-CD1 4.41Å; F62-I100 HydrophobicContact CZ-CG1 3.88Å; D68-I100 HydrophobicContact CB-CD1 3.77Å; D68-I100 WeakPolarHBondContact OD1-CD1 3.36Å; R71-I100 HydrophobicContact CB-CG2 3.93Å; Y72-I100 VanDerWaalsContact CD2-O 3.32Å; Y72-I100 WeakPolarHBondContact CD2-O 3.4Å; L75-I100 HydrophobicContact CD1-CB 4.19Å; L75-I100 HydrophobicContact CD1-CG2 3.82Å; F97-I100 WeakPolarHBondContact O-CB 3.33Å; F97-I100 PolarHBondContact O-N 3.48Å; F97-I100 VanDerWaalsContact O-N 3.08Å; M98-I100 PolarHBondContact O-N 2.85Å; M98-I100 VanDerWaalsContact O-N 3.16Å; I100-Y102 VanDerWaalsContact C-N 3.35Å; I100-T105 WeakPolarHBondContact O-CB 3.47Å
101V96.4Very high94.6Very high0 Ų034 Ų340%019%0.186CC..Hα-helixtrans-81.5-15.3-176.2-59.80000113.8L75 M76 F86 L90 F97 M98 G172 L176L75-V101 HydrophobicContact CB-CG1 4.2Å; L75-V101 HydrophobicContact CD1-CG1 3.59Å; M76-V101 HydrophobicContact CE-CB 4.44Å; M76-V101 HydrophobicContact CE-CG1 4.16Å; F86-V101 HydrophobicContact CE2-CG1 4.31Å; F86-V101 HydrophobicContact CZ-CG1 4.29Å; L90-V101 HydrophobicContact CD1-CG1 4.13Å; L90-V101 HydrophobicContact CD2-CG1 4.24Å; L90-V101 HydrophobicContact CD2-CG2 4.01Å; L90-V101 HydrophobicContact CG-CG1 4.34Å; F97-V101 PolarHBondContact O-N 3.45Å; F97-V101 VanDerWaalsContact O-N 3.12Å; M98-V101 PolarHBondContact O-N 3.24Å; V101-G172 WeakPolarHBondContact O-CA 3.46Å; V101-L176 HydrophobicContact CG2-CD2 4.12Å
102Y93.4Very high94.5Very high14 Ų1435.5 Ų35.56%0.05519%0.19CC..SBendtrans-135.6-144.9176.1-163.6-123.5000109.9M98 I100 P104 T105 V106 I169 K173 L176 E245M98-Y102 PolarHBondContact O-N 2.96Å; I100-Y102 VanDerWaalsContact C-N 3.35Å; Y102-P104 CarbonylContact O-C 3.46Å; Y102-T105 PolarHBondContact O-N 3.41Å; Y102-T105 VanDerWaalsContact O-N 3.09Å; Y102-V106 HydrophobicContact CD2-CG1 3.98Å; Y102-V106 HydrophobicContact CE2-CG1 4.49Å; Y102-V106 HydrophobicContact CG-CG1 4.47Å; Y102-V106 WeakPolarHBondContact O-CB 3.36Å; Y102-V106 WeakPolarHBondContact O-CG1 3.29Å; Y102-V106 PolarHBondContact O-N 3.13Å; Y102-I169 HydrophobicContact CE2-CG2 4.35Å; Y102-K173 HydrophobicContact CE2-CB 3.97Å; Y102-K173 HydrophobicContact CE2-CG 4.36Å; Y102-K173 PolarHBondContact OH-NZ 2.91Å; Y102-L176 HydrophobicContact CD1-CD1 3.53Å; Y102-L176 HydrophobicContact CE1-CD1 4.33Å; Y102-L176 HydrophobicContact CG-CD1 3.68Å; Y102-L176 HydrophobicContact CG-CG 4.5Å; Y102-E245 PolarHBondContact OH-OE1 3.34Å
103T85.5Confident94.5Very high34 Ų3433.3 Ų33.321%0.20917%0.172CC..THydrogen-bonded Turntrans-65.8133-176.754.70000111.8P99P99-T103 WeakPolarHBondContact CA-O 3.34Å
104P89.8Confident94.4Very high53 Ų5330.6 Ų30.634%0.34416%0.158SC..THydrogen-bonded Turncis-93.4-19.38.134.7-34.7000115.1P99 Y102 V106 G107 P409P99-P104 WeakPolarHBondContact O-CD 3.34Å; Y102-P104 CarbonylContact O-C 3.46Å; P104-V106 VanDerWaalsContact C-N 3.31Å; P104-V106 PolarHBondContact O-N 3.13Å; P104-G107 PolarHBondContact O-N 2.6Å; P104-G107 VanDerWaalsContact O-N 3.09Å; P104-P409 HydrophobicContact CB-CB 4.02Å
105T94.4Very high94.5Very high10 Ų1035 Ų356%0.06118%0.18CC..Hα-helixtrans-65-31.5-166.9-60.10000113.7D68 Y72 P99 I100 Y102 G107 L108 A109D68-T105 HydrophobicContact CB-CG2 4.13Å; D68-T105 WeakPolarHBondContact O-CG2 3.49Å; Y72-T105 HydrophobicContact CG-CG2 4.45Å; P99-T105 WeakPolarHBondContact O-CB 3.04Å; P99-T105 PolarHBondContact O-N 3.28Å; P99-T105 PolarHBondContact O-OG1 3.02Å; P99-T105 VanDerWaalsContact O-OG1 3.12Å; I100-T105 WeakPolarHBondContact O-CB 3.47Å; Y102-T105 PolarHBondContact O-N 3.41Å; Y102-T105 VanDerWaalsContact O-N 3.09Å; T105-G107 PolarHBondContact O-N 3.32Å; T105-L108 WeakPolarHBondContact O-CB 3.35Å; T105-L108 PolarHBondContact O-N 3.45Å; T105-L108 VanDerWaalsContact O-N 3.16Å; T105-A109 PolarHBondContact O-N 3.14Å
106V94.6Very high94.5Very high1 Ų131.3 Ų31.31%0.00617%0.165CC..Hα-helixtrans-59.2-31.5176.272.90000112.6Y72 Y102 P104 A109 C110 G168 I169Y72-V106 HydrophobicContact CE2-CG2 4.36Å; Y102-V106 HydrophobicContact CD2-CG1 3.98Å; Y102-V106 HydrophobicContact CE2-CG1 4.49Å; Y102-V106 HydrophobicContact CG-CG1 4.47Å; Y102-V106 WeakPolarHBondContact O-CB 3.36Å; Y102-V106 WeakPolarHBondContact O-CG1 3.29Å; Y102-V106 PolarHBondContact O-N 3.13Å; P104-V106 VanDerWaalsContact C-N 3.31Å; P104-V106 PolarHBondContact O-N 3.13Å; V106-A109 CarbonylContact O-C 3.45Å; V106-A109 WeakPolarHBondContact O-CB 3.34Å; V106-A109 PolarHBondContact O-N 3Å; V106-C110 PolarHBondContact O-N 2.93Å; V106-C110 PolarHBondContact O-SG 3.08Å; V106-G168 VanDerWaalsContact CG2-O 3.3Å; V106-G168 WeakPolarHBondContact CG2-O 3.13Å; V106-I169 HydrophobicContact CB-CD1 4.48Å; V106-I169 HydrophobicContact CG1-CD1 3.67Å; V106-I169 HydrophobicContact CG2-CD1 4.06Å
107G91.5Very high94.4Very high9 Ų932 Ų329%0.09317%0.168CC..Hα-helixtrans-65.8-45.2177.200000111.6P104 T105 A109 C110 Q111 L159P104-G107 PolarHBondContact O-N 2.6Å; P104-G107 VanDerWaalsContact O-N 3.09Å; T105-G107 PolarHBondContact O-N 3.32Å; G107-A109 VanDerWaalsContact C-N 3.28Å; G107-A109 PolarHBondContact O-N 2.98Å; G107-C110 WeakPolarHBondContact O-CB 3.43Å; G107-C110 PolarHBondContact O-N 3.43Å; G107-C110 VanDerWaalsContact O-N 3.16Å; G107-Q111 PolarHBondContact O-N 3.5Å; G107-L159 VanDerWaalsContact C-CD1 3.48Å; G107-L159 VanDerWaalsContact CA-CD1 3.45Å; G107-L159 WeakPolarHBondContact O-CD1 3.11Å
108L93.6Very high94Very high80 Ų8039 Ų3942%0.41920%0.195SC..Hα-helixtrans-61-40.8172.4176.361.4000111F69 T105 C110 Q111 Q112F69-L108 HydrophobicContact CB-CD2 4.11Å; F69-L108 HydrophobicContact CD2-CG 4.44Å; T105-L108 WeakPolarHBondContact O-CB 3.35Å; T105-L108 PolarHBondContact O-N 3.45Å; T105-L108 VanDerWaalsContact O-N 3.16Å; L108-C110 VanDerWaalsContact C-N 3.3Å; L108-C110 PolarHBondContact O-N 3.08Å; L108-Q111 PolarHBondContact O-N 2.94Å; L108-Q112 HydrophobicContact CD1-CG 4.36Å; L108-Q112 PolarHBondContact O-N 2.88Å; L108-Q112 VanDerWaalsContact O-N 3.08Å
109A95Very high93.7Very high0 Ų043.4 Ų43.40%021%0.214CC..Hα-helixtrans-63.7-35.5175.800000113F69 Y72 T105 V106 G107 Q112 Y113F69-A109 HydrophobicContact CD2-CB 4.34Å; F69-A109 HydrophobicContact CE2-CB 3.97Å; Y72-A109 HydrophobicContact CD1-CB 3.64Å; Y72-A109 HydrophobicContact CD2-CB 4.36Å; Y72-A109 HydrophobicContact CE1-CB 3.32Å; Y72-A109 HydrophobicContact CE2-CB 4.07Å; Y72-A109 HydrophobicContact CG-CB 4.15Å; T105-A109 PolarHBondContact O-N 3.14Å; V106-A109 CarbonylContact O-C 3.45Å; V106-A109 WeakPolarHBondContact O-CB 3.34Å; V106-A109 PolarHBondContact O-N 3Å; G107-A109 VanDerWaalsContact C-N 3.28Å; G107-A109 PolarHBondContact O-N 2.98Å; A109-Q112 CarbonylContact O-C 3.47Å; A109-Q112 PolarHBondContact O-N 3.28Å; A109-Y113 VanDerWaalsContact O-CA 3.24Å; A109-Y113 WeakPolarHBondContact O-CA 3.38Å; A109-Y113 WeakPolarHBondContact O-CB 3.22Å; A109-Y113 PolarHBondContact O-N 3.34Å
110C96.3Very high93.5Very high0 Ų046.1 Ų46.10%023%0.232CC..Hα-helixtrans-64.9-43.6171.7-65.10000110.8V106 G107 L108 Q112 Y113 L162 N165V106-C110 PolarHBondContact O-N 2.93Å; V106-C110 PolarHBondContact O-SG 3.08Å; G107-C110 WeakPolarHBondContact O-CB 3.43Å; G107-C110 PolarHBondContact O-N 3.43Å; G107-C110 VanDerWaalsContact O-N 3.16Å; L108-C110 VanDerWaalsContact C-N 3.3Å; L108-C110 PolarHBondContact O-N 3.08Å; C110-Q112 PolarHBondContact O-N 3.49Å; C110-Y113 VanDerWaalsContact O-CB 3.31Å; C110-Y113 WeakPolarHBondContact O-CB 3.22Å; C110-Y113 PolarHBondContact O-N 3.38Å; C110-Y113 VanDerWaalsContact O-N 3.13Å; C110-L162 HydrophobicContact CB-CD1 3.63Å; C110-N165 WeakPolarHBondContact CB-O 3.46Å; C110-N165 VanDerWaalsContact O-CB 3.25Å; C110-N165 WeakPolarHBondContact O-CB 3.32Å
111Q95.8Very high93.3Very high89 Ų8948.1 Ų48.142%0.41624%0.238SC..Hα-helixtrans-60.7-31.1176.4-67.2-178.6-63.300113G107 L108 L159 L162G107-Q111 PolarHBondContact O-N 3.5Å; L108-Q111 PolarHBondContact O-N 2.94Å; Q111-L159 HydrophobicContact CG-CD1 4.12Å; Q111-L162 HydrophobicContact CG-CD1 4.02Å; Q111-L162 HydrophobicContact CG-CD2 4.25Å
112Q96.9Very high93.3Very high77 Ų7748.6 Ų48.636%0.3624%0.244SC..THydrogen-bonded Turntrans-995.6179.3-60.4-60.4-66.200113.5F69 L108 A109 C110 S114 L115 V116F69-Q112 HydrophobicContact CE2-CB 4.18Å; F69-Q112 HydrophobicContact CZ-CB 3.74Å; F69-Q112 HydrophobicContact CZ-CG 4.27Å; L108-Q112 HydrophobicContact CD1-CG 4.36Å; L108-Q112 PolarHBondContact O-N 2.88Å; L108-Q112 VanDerWaalsContact O-N 3.08Å; A109-Q112 CarbonylContact O-C 3.47Å; A109-Q112 PolarHBondContact O-N 3.28Å; C110-Q112 PolarHBondContact O-N 3.49Å; Q112-S114 PolarHBondContact O-N 2.94Å; Q112-L115 WeakPolarHBondContact O-CB 3.29Å; Q112-L115 PolarHBondContact O-N 3.38Å; Q112-V116 WeakPolarHBondContact O-CG2 3.49Å; Q112-V116 PolarHBondContact O-N 3.5Å; Q112-V116 VanDerWaalsContact O-N 3.14Å
113Y97.1Very high93.5Very high24 Ų2448.7 Ų48.79%0.09425%0.245CC..Hα-helixtrans-61-42-162.8-155.9-96.6000113A109 C110 L115 V116 F117 N165 M167 I209A109-Y113 VanDerWaalsContact O-CA 3.24Å; A109-Y113 WeakPolarHBondContact O-CA 3.38Å; A109-Y113 WeakPolarHBondContact O-CB 3.22Å; A109-Y113 PolarHBondContact O-N 3.34Å; C110-Y113 VanDerWaalsContact O-CB 3.31Å; C110-Y113 WeakPolarHBondContact O-CB 3.22Å; C110-Y113 PolarHBondContact O-N 3.38Å; C110-Y113 VanDerWaalsContact O-N 3.13Å; Y113-L115 VanDerWaalsContact C-N 3.3Å; Y113-L115 PolarHBondContact O-N 2.87Å; Y113-V116 PolarHBondContact O-N 3.31Å; Y113-F117 HydrophobicContact CE1-CD2 4.14Å; Y113-F117 WeakPolarHBondContact O-CB 3.26Å; Y113-F117 PolarHBondContact O-N 3.04Å; Y113-N165 HydrophobicContact CG-CB 4.5Å; Y113-M167 HydrophobicContact CE1-CB 4.2Å; Y113-M167 HydrophobicContact CE1-CG 4.45Å; Y113-M167 WeakPolarHBondContact OH-CG 3.42Å; Y113-I209 HydrophobicContact CD1-CD1 3.94Å; Y113-I209 HydrophobicContact CE1-CD1 4.3Å
114S96.8Very high94.2Very high12 Ų1250.2 Ų50.28%0.08425%0.249CC..Hα-helixtrans-60.7-36.9176.1-73.80000113Q112 N165 L207 Y208 I209Q112-S114 PolarHBondContact O-N 2.94Å; S114-N165 PolarHBondContact N-OD1 3.13Å; S114-N165 PolarHBondContact OG-ND2 2.96Å; S114-N165 PolarHBondContact OG-OD1 2.84Å; S114-L207 WeakPolarHBondContact CB-O 3.44Å; S114-Y208 WeakPolarHBondContact OG-CA 3.45Å; S114-I209 PolarHBondContact OG-N 2.91Å
115L95.6Very high94.6Very high109 Ų10947.7 Ų47.757%0.57123%0.232SC*.Hα-helixtrans-72.1-41.7179.4175.964.2000112Q112 Y113 L207Q112-L115 WeakPolarHBondContact O-CB 3.29Å; Q112-L115 PolarHBondContact O-N 3.38Å; Y113-L115 VanDerWaalsContact C-N 3.3Å; Y113-L115 PolarHBondContact O-N 2.87Å; L115-L207 HydrophobicContact CD1-CD1 3.86Å
116V92.9Very high94.8Very high31 Ų3148.1 Ų48.119%0.18824%0.236CC..Hα-helixtrans-98.39.4-173.9-58.90000113.9F69 L73 Q112 Y113 R118F69-V116 HydrophobicContact CE1-CG1 3.84Å; F69-V116 HydrophobicContact CE2-CG2 4.43Å; F69-V116 HydrophobicContact CZ-CB 4.24Å; F69-V116 HydrophobicContact CZ-CG1 3.52Å; F69-V116 HydrophobicContact CZ-CG2 3.89Å; L73-V116 HydrophobicContact CD1-CG1 4.47Å; L73-V116 HydrophobicContact CD2-CB 4.08Å; L73-V116 HydrophobicContact CD2-CG2 4.01Å; Q112-V116 WeakPolarHBondContact O-CG2 3.49Å; Q112-V116 PolarHBondContact O-N 3.5Å; Q112-V116 VanDerWaalsContact O-N 3.14Å; Y113-V116 PolarHBondContact O-N 3.31Å; V116-R118 WeakPolarHBondContact O-CG 3.35Å; V116-R118 PolarHBondContact O-N 2.88Å
117F94.4Very high95Very high86 Ų8648.3 Ų48.338%0.37724%0.237SC..  trans-56.1123.1179.2-174.8-96.9000110.7Y113 P120 I209Y113-F117 HydrophobicContact CE1-CD2 4.14Å; Y113-F117 WeakPolarHBondContact O-CB 3.26Å; Y113-F117 PolarHBondContact O-N 3.04Å; F117-P120 HydrophobicContact CE2-CB 4.3Å; F117-P120 HydrophobicContact CZ-CB 3.88Å; F117-I209 HydrophobicContact CD2-CD1 3.83Å; F117-I209 HydrophobicContact CE2-CD1 4.23Å; F117-I209 HydrophobicContact CG-CD1 4.4Å
118R87.7Confident95.4Very high150 Ų15053.3 Ų53.357%0.56626%0.258SS*.  trans-129.3-93.8-177-74.4172179-1733.1110.5D77 V116D77-R118 IonicContact OD1-NH1 3.59Å; D77-R118 IonicContact OD2-NH1 3.01Å; D77-R118 PolarHBondContact OD2-NH1 2.9Å; V116-R118 WeakPolarHBondContact O-CG 3.35Å; V116-R118 PolarHBondContact O-N 2.88Å
119K88.6Confident95.6Very high95 Ų9551.8 Ų51.841%0.41325%0.25SS..SBendtrans-89.4121.7175.4-71.3177.6-178.8175.10108.1D80 R121D80-K119 HydrophobicContact CB-CD 3.54Å; D80-K119 PolarHBondContact O-NZ 3.03Å; D80-K119 VanDerWaalsContact OD2-CB 3.27Å; D80-K119 WeakPolarHBondContact OD2-CB 3.42Å; D80-K119 WeakPolarHBondContact OD2-CD 3.32Å; K119-R121 PolarHBondContact O-N 3.49Å
120P89.8Confident95.8Very high88 Ų8856.1 Ų56.157%0.57127%0.267SS*.  trans-64.4137.3177.624.4-31.5000110.4F117F117-P120 HydrophobicContact CE2-CB 4.3Å; F117-P120 HydrophobicContact CZ-CB 3.88Å
121R93.1Very high95.9Very high48 Ų4858.8 Ų58.818%0.18129%0.294CS..  trans-127.9136.8172.4-76-74.8-82.1-1717.4108.9Q79 D80 K119 M167 V171Q79-R121 VanDerWaalsContact CD-NH2 3.27Å; Q79-R121 VanDerWaalsContact NE2-NH2 3.15Å; D80-R121 WeakPolarHBondContact OD1-CD 3.36Å; D80-R121 IonicContact OD1-CZ 2.64Å; D80-R121 IonicContact OD1-NE 3.2Å; D80-R121 IonicContact OD1-NH1 3.31Å; K119-R121 PolarHBondContact O-N 3.49Å; R121-M167 WeakPolarHBondContact O-CG 3.3Å; R121-M167 VanDerWaalsContact O-SD 3.38Å; R121-V171 HydrophobicContact CB-CG2 3.97Å
122G96.4Very high96Very high11 Ų1160.2 Ų60.211%0.11330%0.3CS..SBendtrans83.3-176.5-175.600000113.5P190G122-P190 CarbonylContact C-O 3.55Å; G122-P190 WeakPolarHBondContact CA-O 3.01Å
123L98.6Very high96.1Very high16 Ų1656.6 Ų56.68%0.08428%0.283CS..EExtended strand (participates in β ladder)trans-115.4134.5-177.4-165.567.8000110.3I125 V136 L137 M167 L189 P190 V191 I192L123-I125 HydrophobicContact CD2-CD1 4.13Å; L123-I125 HydrophobicContact CD2-CG1 4.2Å; L123-I125 HydrophobicContact CG-CG1 4.18Å; L123-V136 HydrophobicContact CD1-CG1 3.98Å; L123-V136 HydrophobicContact CD2-CG1 4.18Å; L123-V136 HydrophobicContact CG-CG1 4.08Å; L123-L137 HydrophobicContact CD2-CD2 3.7Å; L123-M167 VanDerWaalsContact O-CE 3.24Å; L123-M167 WeakPolarHBondContact O-CE 3.18Å; L123-L189 HydrophobicContact CB-CD1 4.06Å; L123-P190 PolarHBondContact N-O 3.01Å; L123-V191 HydrophobicContact CB-CG2 4.5Å; L123-V191 WeakPolarHBondContact O-CA 3.29Å; L123-I192 PolarHBondContact O-N 2.82Å
124F98.8Very high96.2Very high65 Ų6558 Ų5829%0.28530%0.3SS..EExtended strand (participates in β ladder)trans-106.6117179.9-58.9-103.2000107.4C164 M167 I192F124-C164 VanDerWaalsContact CD1-SG 3.53Å; F124-M167 HydrophobicContact CD1-CE 4.37Å; F124-M167 HydrophobicContact CD2-CE 4.29Å; F124-M167 HydrophobicContact CE1-CB 4.1Å; F124-M167 HydrophobicContact CE1-CE 4.15Å; F124-M167 HydrophobicContact CE1-CG 4.12Å; F124-M167 HydrophobicContact CE2-CE 4.06Å; F124-M167 HydrophobicContact CG-CE 4.42Å; F124-M167 HydrophobicContact CZ-CB 4.29Å; F124-M167 HydrophobicContact CZ-CE 3.99Å; F124-M167 HydrophobicContact CZ-CG 3.83Å; F124-I192 HydrophobicContact CB-CG2 4.01Å; F124-I192 HydrophobicContact CD1-CG2 3.18Å; F124-I192 HydrophobicContact CE1-CG2 3.73Å; F124-I192 HydrophobicContact CG-CG2 3.74Å
125I98.9Very high96.2Very high0 Ų060.6 Ų60.60%032%0.318CS..EExtended strand (participates in β ladder)trans-121.7117.1179.6-51.3172000106.5L123 D129 I133 V136 V191 I192 L193 D194 F224 F228L123-I125 HydrophobicContact CD2-CD1 4.13Å; L123-I125 HydrophobicContact CD2-CG1 4.2Å; L123-I125 HydrophobicContact CG-CG1 4.18Å; I125-D129 HydrophobicContact CG2-CB 4.31Å; I125-I133 HydrophobicContact CD1-CG2 4.14Å; I125-I133 HydrophobicContact CG2-CD1 4.15Å; I125-I133 HydrophobicContact CG2-CG1 3.78Å; I125-I133 HydrophobicContact CG2-CG2 4.36Å; I125-V136 HydrophobicContact CG1-CG1 4.12Å; I125-V191 HydrophobicContact CD1-CG1 3.82Å; I125-V191 HydrophobicContact CG1-CG1 4.28Å; I125-I192 PolarHBondContact N-O 2.88Å; I125-L193 HydrophobicContact CB-CD2 3.97Å; I125-L193 HydrophobicContact CD1-CD2 4.34Å; I125-L193 HydrophobicContact CG2-CD2 4.48Å; I125-L193 CarbonylContact O-C 3.53Å; I125-L193 VanDerWaalsContact O-CA 3.3Å; I125-L193 WeakPolarHBondContact O-CA 3.5Å; I125-D194 PolarHBondContact O-N 3.08Å; I125-F224 HydrophobicContact CG2-CE2 3.96Å; I125-F224 HydrophobicContact CG2-CZ 3.83Å; I125-F228 HydrophobicContact CD1-CD2 3.86Å; I125-F228 HydrophobicContact CD1-CE2 3.86Å
126S98.8Very high96.4Very high20 Ų2056.7 Ų56.714%0.1430%0.299CS..EExtended strand (participates in β ladder)trans-97.7161.4-176.177.60000111.7H128 D129 D194 F224S126-H128 PolarHBondContact O-N 2.89Å; S126-H128 VanDerWaalsContact O-N 3.11Å; S126-H128 PolarHBondContact OG-N 3.13Å; S126-D129 WeakPolarHBondContact CA-OD2 3.38Å; S126-D129 WeakPolarHBondContact CB-OD2 3.28Å; S126-D129 PolarHBondContact N-OD2 3.3Å; S126-D129 WeakPolarHBondContact O-CB 3.32Å; S126-D129 PolarHBondContact O-N 3Å; S126-D129 PolarHBondContact OG-N 3.47Å; S126-D129 PolarHBondContact OG-OD2 3.21Å; S126-D194 CarbonylContact C-O 3.18Å; S126-D194 VanDerWaalsContact CA-O 3.23Å; S126-D194 WeakPolarHBondContact CA-O 3.46Å; S126-F224 WeakPolarHBondContact O-CE2 3.38Å; S126-F224 VanDerWaalsContact O-CZ 3.31Å; S126-F224 WeakPolarHBondContact O-CZ 3.47Å
127I98.8Very high96.7Very high5 Ų555.2 Ų55.23%0.02629%0.29CS..G310 helixtrans-57.5-24.7171.7-166.957.2000112.8D129 R130 D194 V195 L211 V216 E220 F224I127-D129 VanDerWaalsContact C-N 3.27Å; I127-D129 PolarHBondContact O-N 2.98Å; I127-R130 WeakPolarHBondContact O-CB 3.24Å; I127-R130 PolarHBondContact O-N 2.88Å; I127-D194 PolarHBondContact N-O 3.07Å; I127-V195 HydrophobicContact CB-CB 4.32Å; I127-V195 HydrophobicContact CB-CG1 4.12Å; I127-V195 HydrophobicContact CD1-CG1 4.4Å; I127-L211 HydrophobicContact CG2-CD1 3.95Å; I127-V216 HydrophobicContact CD1-CG1 4.39Å; I127-V216 HydrophobicContact CG1-CB 4.08Å; I127-V216 HydrophobicContact CG1-CG1 4.11Å; I127-V216 HydrophobicContact CG1-CG2 4.03Å; I127-V216 HydrophobicContact CG2-CG2 4.12Å; I127-E220 HydrophobicContact CD1-CG 4.35Å; I127-F224 HydrophobicContact CD1-CB 3.54Å; I127-F224 HydrophobicContact CD1-CD1 3.82Å; I127-F224 HydrophobicContact CD1-CD2 4.1Å; I127-F224 HydrophobicContact CD1-CG 3.55Å
128H98.7Very high96.9Very high114 Ų11456.2 Ų56.253%0.52830%0.299SS..G310 helixtrans-79.4-9.5177.9-58.5-60000113.2S126 R130 Q213S126-H128 PolarHBondContact O-N 2.89Å; S126-H128 VanDerWaalsContact O-N 3.11Å; S126-H128 PolarHBondContact OG-N 3.13Å; H128-R130 VanDerWaalsContact C-N 3.29Å; H128-Q213 PolarHBondContact CE1-OE1 2.94Å; H128-Q213 PolarHBondContact NE2-OE1 3.28Å
129D98.8Very high97.4Very high48 Ų4852.9 Ų52.926%0.25730%0.304SS..G310 helixtrans-895.3172.6-59.2-61.8000112.6I125 S126 I127 G131 H132 I133 V136I125-D129 HydrophobicContact CG2-CB 4.31Å; S126-D129 WeakPolarHBondContact CA-OD2 3.38Å; S126-D129 WeakPolarHBondContact CB-OD2 3.28Å; S126-D129 PolarHBondContact N-OD2 3.3Å; S126-D129 WeakPolarHBondContact O-CB 3.32Å; S126-D129 PolarHBondContact O-N 3Å; S126-D129 PolarHBondContact OG-N 3.47Å; S126-D129 PolarHBondContact OG-OD2 3.21Å; I127-D129 VanDerWaalsContact C-N 3.27Å; I127-D129 PolarHBondContact O-N 2.98Å; D129-G131 PolarHBondContact O-N 2.82Å; D129-H132 CarbonylContact O-C 3.58Å; D129-H132 WeakPolarHBondContact O-CA 3.33Å; D129-H132 WeakPolarHBondContact O-CB 3.48Å; D129-H132 PolarHBondContact O-N 2.71Å; D129-I133 PolarHBondContact O-N 3.27Å; D129-V136 HydrophobicContact CB-CG2 4.19Å
130R98.3Very high97.8Very high91 Ų9150.4 Ų50.434%0.34329%0.292SS..THydrogen-bonded Turntrans-55.3131.2174.8-173.8-162176106.6-4.8110.9I127 H128 H132 E220 D223 F224 E227I127-R130 WeakPolarHBondContact O-CB 3.24Å; I127-R130 PolarHBondContact O-N 2.88Å; H128-R130 VanDerWaalsContact C-N 3.29Å; R130-H132 VanDerWaalsContact C-N 3.31Å; R130-E220 PolarHBondContact NH1-O 2.83Å; R130-D223 VanDerWaalsContact CZ-CB 3.44Å; R130-D223 IonicContact CZ-OD2 2.71Å; R130-D223 IonicContact NH1-OD2 2.72Å; R130-D223 IonicContact NH2-OD2 3.96Å; R130-D223 PolarHBondContact NH2-OD2 3.18Å; R130-F224 HydrophobicContact CB-CD2 4.25Å; R130-E227 WeakPolarHBondContact CA-OE2 3.32Å; R130-E227 WeakPolarHBondContact CG-OE2 3.5Å
131G98.4Very high98.2Very high56 Ų5651 Ų5158%0.57730%0.296SS*.THydrogen-bonded Turntrans87.5-4.4-171.200000113.7D129 E227D129-G131 PolarHBondContact O-N 2.82Å; G131-E227 VanDerWaalsContact C-OE1 3.26Å; G131-E227 VanDerWaalsContact CA-OE1 3.27Å; G131-E227 WeakPolarHBondContact CA-OE1 3.27Å; G131-E227 PolarHBondContact N-OE1 3.43Å; G131-E227 PolarHBondContact N-OE2 3.08Å
132H98.8Very high98.4Very high119 Ų11950.9 Ų50.955%0.55130%0.297SS*.  trans-134.97.8-170.5-58.9-66.9000113.9D129 R130 A134 S135 V136 E227D129-H132 CarbonylContact O-C 3.58Å; D129-H132 WeakPolarHBondContact O-CA 3.33Å; D129-H132 WeakPolarHBondContact O-CB 3.48Å; D129-H132 PolarHBondContact O-N 2.71Å; R130-H132 VanDerWaalsContact C-N 3.31Å; H132-A134 VanDerWaalsContact C-N 3.27Å; H132-A134 PolarHBondContact O-N 3.45Å; H132-S135 WeakPolarHBondContact O-CA 3.3Å; H132-S135 WeakPolarHBondContact O-CB 3.28Å; H132-S135 PolarHBondContact O-N 2.9Å; H132-S135 PolarHBondContact O-OG 2.89Å; H132-V136 PolarHBondContact O-N 2.89Å; H132-E227 PolarHBondContact N-OE1 3.37Å
133I98.8Very high98.5Very high0 Ų056.2 Ų56.20%032%0.323CS..Hα-helixtrans-57-41.5-177-63.9178.9000111.6I125 D129 S135 V136 L137 F224 E227 F228I125-I133 HydrophobicContact CD1-CG2 4.14Å; I125-I133 HydrophobicContact CG2-CD1 4.15Å; I125-I133 HydrophobicContact CG2-CG1 3.78Å; I125-I133 HydrophobicContact CG2-CG2 4.36Å; D129-I133 PolarHBondContact O-N 3.27Å; I133-S135 PolarHBondContact O-N 3.42Å; I133-V136 PolarHBondContact O-N 2.87Å; I133-L137 HydrophobicContact CG2-CD1 4.32Å; I133-L137 HydrophobicContact CG2-CG 4.26Å; I133-L137 WeakPolarHBondContact O-CG 3.27Å; I133-L137 PolarHBondContact O-N 3.34Å; I133-F224 HydrophobicContact CD1-CD2 3.86Å; I133-F224 HydrophobicContact CD1-CE2 3.6Å; I133-F224 HydrophobicContact CD1-CZ 4.43Å; I133-F224 HydrophobicContact CG1-CE2 4.15Å; I133-E227 HydrophobicContact CB-CG 4.33Å; I133-E227 HydrophobicContact CD1-CB 3.96Å; I133-E227 HydrophobicContact CD1-CG 3.82Å; I133-E227 HydrophobicContact CG1-CG 4.2Å; I133-E227 WeakPolarHBondContact CG1-OE1 3.35Å; I133-E227 PolarHBondContact N-OE1 3.28Å; I133-F228 HydrophobicContact CD1-CB 3.94Å; I133-F228 HydrophobicContact CG2-CD2 4.47Å
134A98.6Very high98.5Very high54 Ų5459.6 Ų59.645%0.44634%0.344SS..Hα-helixtrans-55.2-34.9176.200000113.2H132 N138H132-A134 VanDerWaalsContact C-N 3.27Å; H132-A134 PolarHBondContact O-N 3.45Å; A134-N138 PolarHBondContact O-ND2 2.91Å
135S98.6Very high98.5Very high67 Ų6756.7 Ų56.747%0.46933%0.331SS..Hα-helixtrans-73-39.9176.577.50000112.1H132 I133 L137 N138H132-S135 WeakPolarHBondContact O-CA 3.3Å; H132-S135 WeakPolarHBondContact O-CB 3.28Å; H132-S135 PolarHBondContact O-N 2.9Å; H132-S135 PolarHBondContact O-OG 2.89Å; I133-S135 PolarHBondContact O-N 3.42Å; S135-L137 VanDerWaalsContact C-N 3.32Å; S135-L137 PolarHBondContact O-N 2.83Å; S135-N138 WeakPolarHBondContact O-CB 3.23Å; S135-N138 PolarHBondContact O-N 2.89Å; S135-N138 VanDerWaalsContact O-N 3.09Å
136V98.8Very high98.5Very high27 Ų2759.9 Ų59.916%0.16435%0.345CS..Hα-helixtrans-62.8-40.7176.9-178.40000110.5L123 I125 D129 H132 I133 N138 A139L123-V136 HydrophobicContact CD1-CG1 3.98Å; L123-V136 HydrophobicContact CD2-CG1 4.18Å; L123-V136 HydrophobicContact CG-CG1 4.08Å; I125-V136 HydrophobicContact CG1-CG1 4.12Å; D129-V136 HydrophobicContact CB-CG2 4.19Å; H132-V136 PolarHBondContact O-N 2.89Å; I133-V136 PolarHBondContact O-N 2.87Å; V136-N138 PolarHBondContact O-N 3.27Å; V136-A139 WeakPolarHBondContact O-CB 3.3Å; V136-A139 PolarHBondContact O-N 3.02Å
137L98.7Very high98.5Very high0 Ų058.9 Ų58.90%034%0.339CS..Hα-helixtrans-60.2-27.3175.8-66.2174.8000113L123 I133 S135 A139 W140 L189 V232 K235 Y236L123-L137 HydrophobicContact CD2-CD2 3.7Å; I133-L137 HydrophobicContact CG2-CD1 4.32Å; I133-L137 HydrophobicContact CG2-CG 4.26Å; I133-L137 WeakPolarHBondContact O-CG 3.27Å; I133-L137 PolarHBondContact O-N 3.34Å; S135-L137 VanDerWaalsContact C-N 3.32Å; S135-L137 PolarHBondContact O-N 2.83Å; L137-A139 PolarHBondContact O-N 2.91Å; L137-W140 PolarHBondContact O-N 3.28Å; L137-L189 HydrophobicContact CD2-CD2 4.47Å; L137-V232 HydrophobicContact CD1-CG2 4.19Å; L137-V232 HydrophobicContact CD2-CG2 4.31Å; L137-K235 HydrophobicContact CB-CD 3.48Å; L137-K235 VanDerWaalsContact CB-CD 3.48Å; L137-K235 HydrophobicContact CD1-CB 4.34Å; L137-K235 HydrophobicContact CD1-CD 4.12Å; L137-K235 HydrophobicContact CG-CD 4.4Å; L137-K235 VanDerWaalsContact O-CE 3.29Å; L137-K235 WeakPolarHBondContact O-CE 3.31Å; L137-Y236 HydrophobicContact CD2-CE2 4.14Å
138N98.4Very high98.5Very high107 Ų10758.7 Ų58.757%0.57234%0.337SS*.THydrogen-bonded Turntrans-72.9-12.7177-63.7-30.5000113.5A134 S135 V136 W140 K235A134-N138 PolarHBondContact O-ND2 2.91Å; S135-N138 WeakPolarHBondContact O-CB 3.23Å; S135-N138 PolarHBondContact O-N 2.89Å; S135-N138 VanDerWaalsContact O-N 3.09Å; V136-N138 PolarHBondContact O-N 3.27Å; N138-W140 VanDerWaalsContact C-N 3.26Å; N138-K235 PolarHBondContact OD1-NZ 2.82Å
139A98.4Very high98.5Very high80 Ų8053.2 Ų53.266%0.66131%0.312SS*.THydrogen-bonded Turntrans-76.5-15.7173.200000112.6V136 L137V136-A139 WeakPolarHBondContact O-CB 3.3Å; V136-A139 PolarHBondContact O-N 3.02Å; L137-A139 PolarHBondContact O-N 2.91Å
140W98.3Very high98.5Very high43 Ų4351 Ų5116%0.16330%0.3CS..SBendtrans-74.3130.7177-167.2-109.2000110.8L137 N138 E142 L189L137-W140 PolarHBondContact O-N 3.28Å; N138-W140 VanDerWaalsContact C-N 3.26Å; W140-E142 VanDerWaalsContact C-N 3.29Å; W140-E142 PolarHBondContact O-N 2.9Å; W140-L189 HydrophobicContact CD2-CD1 3.46Å; W140-L189 VanDerWaalsContact CD2-CD1 3.46Å; W140-L189 HydrophobicContact CE3-CD1 3.71Å; W140-L189 HydrophobicContact CG-CD1 3.95Å; W140-L189 HydrophobicContact CH2-CD1 4.06Å; W140-L189 HydrophobicContact CZ2-CD1 3.84Å; W140-L189 HydrophobicContact CZ3-CD1 4Å
141P97Very high98.5Very high100 Ų10046.6 Ų46.665%0.64928%0.284SS*.SBendtrans-75.8-12.8-171.329.6-36.7000114.7
142E97.9Very high98.5Very high45 Ų4544 Ų4421%0.2126%0.256CS..  trans-104.9115.5-179.6-61.1-67.1155.800110.4H23 W140 V144 I145 Q186H23-E142 IonicContact CD2-OE1 3.14Å; W140-E142 VanDerWaalsContact C-N 3.29Å; W140-E142 PolarHBondContact O-N 2.9Å; E142-V144 VanDerWaalsContact C-N 3.31Å; E142-V144 PolarHBondContact O-N 3.02Å; E142-I145 HydrophobicContact CB-CD1 4Å; E142-Q186 WeakPolarHBondContact CB-O 3.5Å; E142-Q186 HydrophobicContact CG-CB 4.28Å
143D97.7Very high98.5Very high123 Ų12338.3 Ų38.366%0.65823%0.23SC*.SBendtrans-74.5-22-179.2-67.9-51.1000113.4Y236D143-Y236 WeakPolarHBondContact O-CD1 3.15Å
144V98.2Very high98.5Very high87 Ų8740 Ų4053%0.52724%0.238SC..  trans-108.985.9-173.9-174.80000110.4E142 K187E142-V144 VanDerWaalsContact C-N 3.31Å; E142-V144 PolarHBondContact O-N 3.02Å; V144-K187 WeakPolarHBondContact O-CA 3.1Å
145I98.8Very high98.4Very high4 Ų440.3 Ų40.32%0.02123%0.228CC..  trans-96.1137.3172.5-56.9-53.7000110.2E142 I148 L189 Y236E142-I145 HydrophobicContact CB-CD1 4Å; I145-I148 HydrophobicContact CG2-CD1 4.13Å; I145-I148 HydrophobicContact CG2-CG1 3.79Å; I145-L189 HydrophobicContact CD1-CB 4.12Å; I145-L189 HydrophobicContact CG1-CB 4.2Å; I145-L189 HydrophobicContact CG1-CD2 4.36Å; I145-L189 HydrophobicContact CG2-CB 3.71Å; I145-L189 HydrophobicContact CG2-CD2 4.45Å; I145-Y236 HydrophobicContact CB-CD1 3.72Å; I145-Y236 HydrophobicContact CB-CD2 3.99Å; I145-Y236 HydrophobicContact CB-CE1 3.88Å; I145-Y236 HydrophobicContact CB-CE2 4.14Å; I145-Y236 HydrophobicContact CB-CG 3.77Å; I145-Y236 HydrophobicContact CG1-CD1 3.92Å; I145-Y236 HydrophobicContact CG1-CD2 4.43Å; I145-Y236 HydrophobicContact CG1-CE1 3.53Å; I145-Y236 HydrophobicContact CG1-CE2 4.1Å; I145-Y236 HydrophobicContact CG1-CG 4.35Å; I145-Y236 HydrophobicContact CG2-CD2 4.42Å
146K98.8Very high98.1Very high67 Ų6737.2 Ų37.229%0.29121%0.206SC..  trans-125-18177.4-62.9-159.8178.5-165.70113.5K187 L241 V466K146-K187 HydrophobicContact CB-CB 4.2Å; K146-K187 HydrophobicContact CD-CD 4Å; K146-K187 HydrophobicContact CG-CB 4.3Å; K146-K187 HydrophobicContact CG-CD 4.1Å; K146-K187 PolarHBondContact N-O 3.35Å; K146-L241 WeakPolarHBondContact O-CB 3.41Å; K146-L241 PolarHBondContact O-N 2.6Å; K146-V466 HydrophobicContact CB-CG1 3.83Å; K146-V466 HydrophobicContact CB-CG2 4.36Å; K146-V466 HydrophobicContact CD-CG1 3.53Å; K146-V466 HydrophobicContact CG-CG1 4.35Å
147A98.9Very high97.5Very high0 Ų038.7 Ų38.70%021%0.212CC..EExtended strand (participates in β ladder)trans-140.2128.1177.300000110.9Y177 K187 C188 L189 L241A147-Y177 HydrophobicContact CB-CD1 4.24Å; A147-Y177 HydrophobicContact CB-CE1 4.11Å; A147-K187 PolarHBondContact N-O 2.91Å; A147-C188 CarbonylContact O-C 3.55Å; A147-C188 VanDerWaalsContact O-CA 3.27Å; A147-C188 WeakPolarHBondContact O-CA 3.26Å; A147-L189 PolarHBondContact O-N 2.89Å; A147-L241 CarbonylContact C-O 3.57Å; A147-L241 WeakPolarHBondContact CA-O 3.45Å; A147-L241 HydrophobicContact CB-CB 4.42Å; A147-L241 HydrophobicContact CB-CD2 4.38Å
148I98.9Very high96.8Very high0 Ų040.4 Ų40.40%023%0.23CC..EExtended strand (participates in β ladder)trans-118.3135.9173.3-72.6159.8000108I145 V150 L189 V191 F228 V232 Y236 L241 Q243I145-I148 HydrophobicContact CG2-CD1 4.13Å; I145-I148 HydrophobicContact CG2-CG1 3.79Å; I148-V150 HydrophobicContact CG2-CB 4.22Å; I148-L189 WeakPolarHBondContact CA-O 3.41Å; I148-L189 HydrophobicContact CD1-CD2 4.17Å; I148-L189 HydrophobicContact CG1-CB 3.82Å; I148-L189 HydrophobicContact CG1-CD2 4.1Å; I148-L189 HydrophobicContact CG1-CG 4.15Å; I148-V191 HydrophobicContact CG2-CB 4.45Å; I148-V191 HydrophobicContact CG2-CG2 3.88Å; I148-F228 HydrophobicContact CG2-CZ 4.29Å; I148-V232 HydrophobicContact CD1-CB 4.32Å; I148-V232 HydrophobicContact CD1-CG1 3.28Å; I148-V232 HydrophobicContact CD1-CG2 4.02Å; I148-Y236 HydrophobicContact CD1-CD2 4.32Å; I148-L241 PolarHBondContact N-O 3.41Å; I148-Q243 PolarHBondContact O-N 3.13Å
149V98.9Very high96.3Very high0 Ų037.9 Ų37.90%022%0.217CC..EExtended strand (participates in β ladder)trans-111.6125161.5177.60000106.3P170 K173 L174 Y177 L189 V191 Q243 E245V149-P170 HydrophobicContact CB-CB 4.23Å; V149-P170 HydrophobicContact CG1-CB 4.07Å; V149-P170 HydrophobicContact CG1-CG 4.37Å; V149-K173 HydrophobicContact CG1-CB 4.38Å; V149-K173 HydrophobicContact CG1-CD 4.23Å; V149-L174 HydrophobicContact CB-CD1 4.35Å; V149-L174 HydrophobicContact CB-CD2 4.37Å; V149-L174 HydrophobicContact CB-CG 4.09Å; V149-L174 HydrophobicContact CG2-CD1 4.44Å; V149-L174 HydrophobicContact CG2-CD2 3.59Å; V149-L174 HydrophobicContact CG2-CG 3.74Å; V149-Y177 HydrophobicContact CG2-CE2 4.03Å; V149-L189 PolarHBondContact N-O 3.38Å; V149-V191 PolarHBondContact O-N 2.9Å; V149-Q243 WeakPolarHBondContact CA-O 3.39Å; V149-Q243 HydrophobicContact CG2-CB 4.2Å; V149-E245 HydrophobicContact CG1-CB 3.96Å; V149-E245 HydrophobicContact CG1-CG 4.5Å
150V98.9Very high96.1Very high0 Ų035.6 Ų35.60%020%0.2CC..EExtended strand (participates in β ladder)trans-123.5141.5-17862.90000110I148 V191 L193 F228 I242 Q243 F244 E245 F247I148-V150 HydrophobicContact CG2-CB 4.22Å; V150-V191 WeakPolarHBondContact CA-O 3.46Å; V150-V191 HydrophobicContact CB-CB 4.15Å; V150-V191 HydrophobicContact CG2-CB 3.97Å; V150-V191 HydrophobicContact CG2-CG1 3.9Å; V150-L193 HydrophobicContact CG2-CD1 3.78Å; V150-L193 HydrophobicContact CG2-CD2 4.25Å; V150-L193 HydrophobicContact CG2-CG 3.61Å; V150-F228 HydrophobicContact CB-CE1 4.32Å; V150-F228 HydrophobicContact CB-CZ 4.13Å; V150-F228 HydrophobicContact CG1-CE1 4.1Å; V150-F228 HydrophobicContact CG1-CZ 4.39Å; V150-F228 HydrophobicContact CG2-CE1 4.15Å; V150-F228 HydrophobicContact CG2-CZ 3.96Å; V150-I242 HydrophobicContact CG1-CG2 4.07Å; V150-Q243 PolarHBondContact N-O 3.5Å; V150-F244 HydrophobicContact CG1-CD1 4.08Å; V150-F244 HydrophobicContact CG1-CE1 4.24Å; V150-F244 HydrophobicContact CG1-CG 4.43Å; V150-E245 PolarHBondContact O-N 3.1Å; V150-F247 WeakPolarHBondContact O-CE2 3.36Å
151T98.9Very high96.1Very high0 Ų034.6 Ų34.60%020%0.198CC..EExtended strand (participates in β ladder)trans-137.9157171-171.40000109.7G153 P170 V191 I192 L193 E245T151-G153 PolarHBondContact OG1-N 2.77Å; T151-P170 HydrophobicContact CG2-CG 3.57Å; T151-V191 PolarHBondContact N-O 3.5Å; T151-I192 HydrophobicContact CG2-CD1 3.49Å; T151-I192 VanDerWaalsContact CG2-CD1 3.49Å; T151-I192 WeakPolarHBondContact O-CA 3.4Å; T151-L193 PolarHBondContact O-N 3.39Å; T151-E245 WeakPolarHBondContact CA-O 3.35Å; T151-E245 WeakPolarHBondContact CB-O 3.42Å; T151-E245 PolarHBondContact OG1-O 3.14Å
152D98.7Very high96.2Very high0 Ų030.2 Ų30.20%017%0.169CC..  trans-1032.7163.569.7-0.1000112.5E154 L193 R215 Y221 F247D152-E154 PolarHBondContact O-N 2.85Å; D152-E154 VanDerWaalsContact OD1-CB 3.31Å; D152-E154 WeakPolarHBondContact OD1-CB 3.18Å; D152-E154 PolarHBondContact OD1-N 2.88Å; D152-E154 VanDerWaalsContact OD1-N 3.15Å; D152-L193 WeakPolarHBondContact CA-O 3.45Å; D152-L193 HydrophobicContact CB-CB 4.29Å; D152-R215 VanDerWaalsContact O-CZ 3.31Å; D152-R215 PolarHBondContact O-NH1 2.89Å; D152-R215 PolarHBondContact O-NH2 2.82Å; D152-R215 IonicContact OD2-NH1 3.35Å; D152-Y221 PolarHBondContact OD2-OH 3.08Å; D152-F247 HydrophobicContact CB-CD1 4.16Å; D152-F247 HydrophobicContact CB-CE1 3.74Å; D152-F247 HydrophobicContact CB-CZ 4.26Å; D152-F247 WeakPolarHBondContact OD2-CD1 3.31Å
153G98.3Very high96.2Very high0 Ų028.1 Ų28.10%016%0.159CC..SBendtrans69.611.317600000115.2T151 D161 L162 G163 R215T151-G153 PolarHBondContact OG1-N 2.77Å; G153-D161 WeakPolarHBondContact O-CA 3.42Å; G153-L162 PolarHBondContact O-N 3.03Å; G153-G163 PolarHBondContact O-N 2.65Å; G153-R215 VanDerWaalsContact C-NH2 3.33Å; G153-R215 PolarHBondContact O-NH2 2.76Å
154E98.4Very high96.2Very high35 Ų3522.5 Ų22.516%0.16413%0.13CC..THydrogen-bonded Turntrans-74.4-28.4-174.3-168.5179.9173.300113D152 G160 D161 R215 R217 A248D152-E154 PolarHBondContact O-N 2.85Å; D152-E154 VanDerWaalsContact OD1-CB 3.31Å; D152-E154 WeakPolarHBondContact OD1-CB 3.18Å; D152-E154 PolarHBondContact OD1-N 2.88Å; D152-E154 VanDerWaalsContact OD1-N 3.15Å; E154-G160 CarbonylContact O-C 3.6Å; E154-D161 VanDerWaalsContact O-CA 3.23Å; E154-D161 WeakPolarHBondContact O-CA 3.5Å; E154-D161 PolarHBondContact O-N 3.4Å; E154-R215 VanDerWaalsContact CA-NH2 3.32Å; E154-R217 IonicContact OE1-CZ 3.86Å; E154-R217 VanDerWaalsContact OE1-CZ 3.31Å; E154-R217 IonicContact OE1-NH1 2.85Å; E154-R217 PolarHBondContact OE1-NH1 3.03Å; E154-R217 IonicContact OE1-NH2 2.74Å; E154-R217 PolarHBondContact OE1-NH2 2.73Å; E154-R217 IonicContact OE2-CZ 3.23Å; E154-R217 IonicContact OE2-NH1 2.77Å; E154-R217 PolarHBondContact OE2-NH1 3.2Å; E154-R217 IonicContact OE2-NH2 2.81Å; E154-A248 HydrophobicContact CB-CB 4.31Å; E154-A248 HydrophobicContact CG-CB 3.85Å; E154-A248 WeakPolarHBondContact OE1-CB 3.43Å; E154-A248 WeakPolarHBondContact OE2-CB 3.38Å
155R95.8Very high96.3Very high61 Ų6118.4 Ų18.423%0.2311%0.105CC..THydrogen-bonded Turntrans-137.958.1-175.7-165.9-173161.4-86.6-10.6111.2L157 D246 N249 E304R155-L157 PolarHBondContact O-N 3.47Å; R155-D246 CarbonylContact C-O 3.08Å; R155-D246 WeakPolarHBondContact CA-O 3.42Å; R155-D246 PolarHBondContact N-O 3.42Å; R155-D246 WeakPolarHBondContact O-CB 3.05Å; R155-N249 WeakPolarHBondContact CD-OD1 3.28Å; R155-N249 PolarHBondContact NE-OD1 2.97Å; R155-N249 VanDerWaalsContact NE-OD1 3.1Å; R155-E304 WeakPolarHBondContact CD-OE1 3.06Å; R155-E304 IonicContact CZ-OE1 2.9Å; R155-E304 IonicContact NE-OE1 2.6Å; R155-E304 IonicContact NH1-OE1 2.76Å; R155-E304 PolarHBondContact NH1-OE1 3.19Å; R155-E304 IonicContact NH1-OE2 3.61Å
156I93.9Very high96.2Very high3 Ų318.2 Ų18.22%0.01510%0.104CC..BIsolated β-bridgetrans-57.8124.6170.7-54.5-46.6000108.8G158 L159 G160 L162 I169 D246I156-G158 PolarHBondContact O-N 2.93Å; I156-G158 VanDerWaalsContact O-N 3.08Å; I156-L159 HydrophobicContact CB-CB 4.36Å; I156-L159 HydrophobicContact CG2-CB 4.32Å; I156-L159 HydrophobicContact CG2-CD1 4.18Å; I156-L159 PolarHBondContact O-N 3.35Å; I156-G160 PolarHBondContact N-O 2.97Å; I156-G160 PolarHBondContact O-N 3.44Å; I156-L162 HydrophobicContact CB-CD1 3.98Å; I156-L162 HydrophobicContact CB-CG 4.2Å; I156-L162 HydrophobicContact CG1-CB 3.9Å; I156-L162 HydrophobicContact CG1-CD1 3.92Å; I156-L162 HydrophobicContact CG1-CG 3.94Å; I156-L162 HydrophobicContact CG2-CD1 4.04Å; I156-I169 HydrophobicContact CD1-CG1 3.9Å; I156-I169 HydrophobicContact CG2-CD1 4.03Å; I156-I169 HydrophobicContact CG2-CG1 3.98Å; I156-D246 WeakPolarHBondContact CA-OD2 3.31Å; I156-D246 HydrophobicContact CD1-CB 3.77Å
157L85.6Confident96.2Very high57 Ų5715 Ų1530%0.2989%0.09SC..THydrogen-bonded Turntrans-51.4115.3-166.7-173.464.9000113.2R155 L159 D246 N408R155-L157 PolarHBondContact O-N 3.47Å; L157-L159 PolarHBondContact O-N 3.43Å; L157-D246 PolarHBondContact N-OD1 2.8Å; L157-N408 HydrophobicContact CD2-CB 3.85Å; L157-N408 HydrophobicContact CG-CB 4.34Å
158G83.1Confident96.1Very high36 Ų3615 Ų1537%0.3719%0.09SC..THydrogen-bonded Turntrans76.6-2.6179.200000115.5I156I156-G158 PolarHBondContact O-N 2.93Å; I156-G158 VanDerWaalsContact O-N 3.08Å
159L89.1Confident96.1Very high55 Ų5515.2 Ų15.229%0.2889%0.091SC..THydrogen-bonded Turntrans-119.5-19.6-175.9-58.6178000113.5G107 Q111 I156 L157 L162G107-L159 VanDerWaalsContact C-CD1 3.48Å; G107-L159 VanDerWaalsContact CA-CD1 3.45Å; G107-L159 WeakPolarHBondContact O-CD1 3.11Å; Q111-L159 HydrophobicContact CG-CD1 4.12Å; I156-L159 HydrophobicContact CB-CB 4.36Å; I156-L159 HydrophobicContact CG2-CB 4.32Å; I156-L159 HydrophobicContact CG2-CD1 4.18Å; I156-L159 PolarHBondContact O-N 3.35Å; L157-L159 PolarHBondContact O-N 3.43Å; L159-L162 HydrophobicContact CB-CD1 4.16Å; L159-L162 HydrophobicContact CD1-CD1 4.22Å
160G93.8Very high96.1Very high31 Ų3115.2 Ų15.232%0.329%0.091SC..BIsolated β-bridgetrans82.5-145.8175.800000113.1E154 I156 L162E154-G160 CarbonylContact O-C 3.6Å; I156-G160 PolarHBondContact N-O 2.97Å; I156-G160 PolarHBondContact O-N 3.44Å; G160-L162 PolarHBondContact O-N 3.4Å
161D98.2Very high96.1Very high23 Ų2315.6 Ų15.612%0.1239%0.093CC..  trans-77.4110.6-175.8-171.8-13.7000110.7G153 E154 G163 T197 E198 N199 R215G153-D161 WeakPolarHBondContact O-CA 3.42Å; E154-D161 VanDerWaalsContact O-CA 3.23Å; E154-D161 WeakPolarHBondContact O-CA 3.5Å; E154-D161 PolarHBondContact O-N 3.4Å; D161-G163 PolarHBondContact OD1-N 3.11Å; D161-T197 PolarHBondContact OD1-OG1 3.09Å; D161-T197 PolarHBondContact OD2-OG1 2.96Å; D161-E198 PolarHBondContact OD2-N 2.62Å; D161-N199 WeakPolarHBondContact O-CB 3.25Å; D161-N199 PolarHBondContact O-ND2 3.03Å; D161-R215 IonicContact OD1-CZ 3.67Å; D161-R215 IonicContact OD1-NE 2.71Å; D161-R215 PolarHBondContact OD1-NE 2.95Å; D161-R215 IonicContact OD1-NH2 3.71Å; D161-R215 PolarHBondContact OD1-NH2 3.25Å; D161-R215 IonicContact OD2-CZ 3.03Å; D161-R215 IonicContact OD2-NE 3.89Å; D161-R215 PolarHBondContact OD2-NE 2.87Å; D161-R215 IonicContact OD2-NH2 3.45Å
162L98.4Very high96Very high8 Ų815.7 Ų15.74%0.0429%0.094CC..  trans-110.66.4173.3-59.1-174.7000112.4C110 Q111 G153 I156 L159 G160 C164 N165 L202C110-L162 HydrophobicContact CB-CD1 3.63Å; Q111-L162 HydrophobicContact CG-CD1 4.02Å; Q111-L162 HydrophobicContact CG-CD2 4.25Å; G153-L162 PolarHBondContact O-N 3.03Å; I156-L162 HydrophobicContact CB-CD1 3.98Å; I156-L162 HydrophobicContact CB-CG 4.2Å; I156-L162 HydrophobicContact CG1-CB 3.9Å; I156-L162 HydrophobicContact CG1-CD1 3.92Å; I156-L162 HydrophobicContact CG1-CG 3.94Å; I156-L162 HydrophobicContact CG2-CD1 4.04Å; L159-L162 HydrophobicContact CB-CD1 4.16Å; L159-L162 HydrophobicContact CD1-CD1 4.22Å; G160-L162 PolarHBondContact O-N 3.4Å; L162-C164 PolarHBondContact O-N 2.93Å; L162-N165 HydrophobicContact CB-CB 4.42Å; L162-N165 VanDerWaalsContact O-CB 3.28Å; L162-N165 WeakPolarHBondContact O-CB 3.29Å; L162-N165 PolarHBondContact O-N 2.97Å; L162-L202 VanDerWaalsContact C-CD1 3.5Å; L162-L202 VanDerWaalsContact O-CD1 3.32Å; L162-L202 WeakPolarHBondContact O-CD1 3.36Å
163G98.6Very high96Very high0 Ų015.7 Ų15.70%09%0.094CC..G310 helixtrans49.7-133.4-18000000112.7G153 D161 N165 G166G153-G163 PolarHBondContact O-N 2.65Å; D161-G163 PolarHBondContact OD1-N 3.11Å; G163-N165 PolarHBondContact O-N 3.46Å; G163-G166 PolarHBondContact O-N 3.49Å; G163-G166 VanDerWaalsContact O-N 3.07Å
164C98.7Very high96Very high5 Ų516.1 Ų16.13%0.03410%0.096CC..G310 helixtrans-62.1-25-179.8-168.10000113.9F124 L162 G166 M167 D194 Y208 G210F124-C164 VanDerWaalsContact CD1-SG 3.53Å; L162-C164 PolarHBondContact O-N 2.93Å; C164-G166 PolarHBondContact O-N 3.23Å; C164-G166 VanDerWaalsContact O-N 3.11Å; C164-M167 PolarHBondContact O-N 3.33Å; C164-D194 WeakPolarHBondContact CB-OD2 3.46Å; C164-Y208 HydrophobicContact CB-CE2 4.26Å; C164-Y208 PolarHBondContact N-OH 3.43Å; C164-G210 VanDerWaalsContact CB-CA 3.41Å
165N98.6Very high96Very high1 Ų114.4 Ų14.41%0.0059%0.089CC..G310 helixtrans-66.2-13.8177.1-71.1-11.9000112.8C110 Y113 S114 L162 G163 M167C110-N165 WeakPolarHBondContact CB-O 3.46Å; C110-N165 VanDerWaalsContact O-CB 3.25Å; C110-N165 WeakPolarHBondContact O-CB 3.32Å; Y113-N165 HydrophobicContact CG-CB 4.5Å; S114-N165 PolarHBondContact N-OD1 3.13Å; S114-N165 PolarHBondContact OG-ND2 2.96Å; S114-N165 PolarHBondContact OG-OD1 2.84Å; L162-N165 HydrophobicContact CB-CB 4.42Å; L162-N165 VanDerWaalsContact O-CB 3.28Å; L162-N165 WeakPolarHBondContact O-CB 3.29Å; L162-N165 PolarHBondContact O-N 2.97Å; G163-N165 PolarHBondContact O-N 3.46Å; N165-M167 PolarHBondContact O-N 2.99Å
166G98.1Very high96.2Very high0 Ų011.6 Ų11.60%08%0.078CC..G310 helixtrans-64.3-10.417300000115.2G163 C164 G168 I169 P170G163-G166 PolarHBondContact O-N 3.49Å; G163-G166 VanDerWaalsContact O-N 3.07Å; C164-G166 PolarHBondContact O-N 3.23Å; C164-G166 VanDerWaalsContact O-N 3.11Å; G166-G168 PolarHBondContact O-N 2.96Å; G166-I169 WeakPolarHBondContact O-CB 3.48Å; G166-I169 PolarHBondContact O-N 3.09Å; G166-P170 VanDerWaalsContact O-CD 3.29Å; G166-P170 WeakPolarHBondContact O-CD 3.43Å
167M98.6Very high96.4Very high0 Ų011.5 Ų11.50%08%0.077CC..G310 helixtrans-54-26.7178.3171.955.582.900113.6Y113 R121 L123 F124 C164 N165 I169 P170 V171 P190 I192Y113-M167 HydrophobicContact CE1-CB 4.2Å; Y113-M167 HydrophobicContact CE1-CG 4.45Å; Y113-M167 WeakPolarHBondContact OH-CG 3.42Å; R121-M167 WeakPolarHBondContact O-CG 3.3Å; R121-M167 VanDerWaalsContact O-SD 3.38Å; L123-M167 VanDerWaalsContact O-CE 3.24Å; L123-M167 WeakPolarHBondContact O-CE 3.18Å; F124-M167 HydrophobicContact CD1-CE 4.37Å; F124-M167 HydrophobicContact CD2-CE 4.29Å; F124-M167 HydrophobicContact CE1-CB 4.1Å; F124-M167 HydrophobicContact CE1-CE 4.15Å; F124-M167 HydrophobicContact CE1-CG 4.12Å; F124-M167 HydrophobicContact CE2-CE 4.06Å; F124-M167 HydrophobicContact CG-CE 4.42Å; F124-M167 HydrophobicContact CZ-CB 4.29Å; F124-M167 HydrophobicContact CZ-CE 3.99Å; F124-M167 HydrophobicContact CZ-CG 3.83Å; C164-M167 PolarHBondContact O-N 3.33Å; N165-M167 PolarHBondContact O-N 2.99Å; M167-I169 PolarHBondContact O-N 2.71Å; M167-P170 WeakPolarHBondContact O-CD 3.29Å; M167-V171 HydrophobicContact CG-CG2 4.35Å; M167-V171 WeakPolarHBondContact O-CG2 3.46Å; M167-V171 PolarHBondContact O-N 3Å; M167-V171 HydrophobicContact SD-CG2 3.95Å; M167-P190 HydrophobicContact SD-CB 4.1Å; M167-I192 HydrophobicContact CB-CB 4.28Å; M167-I192 HydrophobicContact CB-CG2 4.37Å; M167-I192 HydrophobicContact CE-CB 3.78Å; M167-I192 HydrophobicContact CE-CG2 3.46Å; M167-I192 VanDerWaalsContact CE-CG2 3.46Å
168G97.4Very high97Very high0 Ų08.8 Ų8.80%06%0.063CC..Hα-helixtrans-56.8-30.9173.800000113.7V106 G166 G172V106-G168 VanDerWaalsContact CG2-O 3.3Å; V106-G168 WeakPolarHBondContact CG2-O 3.13Å; G166-G168 PolarHBondContact O-N 2.96Å; G168-G172 PolarHBondContact O-N 3.19Å
169I97.9Very high97.8Very high5 Ų57.1 Ų7.13%0.0265%0.046CC..Hα-helixtrans-68.3-56-178.5-57.8-54.4000112.1Y102 V106 I156 G166 M167 V171 G172 K173 E245 D246Y102-I169 HydrophobicContact CE2-CG2 4.35Å; V106-I169 HydrophobicContact CB-CD1 4.48Å; V106-I169 HydrophobicContact CG1-CD1 3.67Å; V106-I169 HydrophobicContact CG2-CD1 4.06Å; I156-I169 HydrophobicContact CD1-CG1 3.9Å; I156-I169 HydrophobicContact CG2-CD1 4.03Å; I156-I169 HydrophobicContact CG2-CG1 3.98Å; G166-I169 WeakPolarHBondContact O-CB 3.48Å; G166-I169 PolarHBondContact O-N 3.09Å; M167-I169 PolarHBondContact O-N 2.71Å; I169-V171 PolarHBondContact O-N 2.84Å; I169-G172 PolarHBondContact O-N 3.47Å; I169-K173 WeakPolarHBondContact O-CB 3.31Å; I169-K173 PolarHBondContact O-N 2.95Å; I169-E245 HydrophobicContact CG2-CG 3.59Å; I169-D246 WeakPolarHBondContact CG2-OD2 3.33Å
170P98.7Very high98.2Very high0 Ų04.5 Ų4.50%03%0.033CC..Hα-helixtrans-52.6-40.9172.9-29.933.6000113.9V149 T151 G166 M167 K173 L174 P190 V191V149-P170 HydrophobicContact CB-CB 4.23Å; V149-P170 HydrophobicContact CG1-CB 4.07Å; V149-P170 HydrophobicContact CG1-CG 4.37Å; T151-P170 HydrophobicContact CG2-CG 3.57Å; G166-P170 VanDerWaalsContact O-CD 3.29Å; G166-P170 WeakPolarHBondContact O-CD 3.43Å; M167-P170 WeakPolarHBondContact O-CD 3.29Å; P170-K173 PolarHBondContact O-N 3.44Å; P170-L174 WeakPolarHBondContact O-CB 3.47Å; P170-L174 WeakPolarHBondContact O-CG 3.35Å; P170-L174 PolarHBondContact O-N 3.36Å; P170-P190 HydrophobicContact CB-CB 3.59Å; P170-V191 WeakPolarHBondContact CG-O 3.38Å
171V98.6Very high98.4Very high7 Ų73 Ų34%0.0422%0.017CC..Hα-helixtrans-63.4-51.2179.3172.90000111.1M76 R121 M167 I169 K173 L174 A175 P190M76-V171 HydrophobicContact SD-CG1 4.37Å; R121-V171 HydrophobicContact CB-CG2 3.97Å; M167-V171 HydrophobicContact CG-CG2 4.35Å; M167-V171 WeakPolarHBondContact O-CG2 3.46Å; M167-V171 PolarHBondContact O-N 3Å; M167-V171 HydrophobicContact SD-CG2 3.95Å; I169-V171 PolarHBondContact O-N 2.84Å; V171-K173 VanDerWaalsContact C-N 3.35Å; V171-K173 PolarHBondContact O-N 3.39Å; V171-L174 PolarHBondContact O-N 3.47Å; V171-A175 PolarHBondContact O-N 3Å; V171-P190 HydrophobicContact CG2-CB 3.94Å; V171-P190 HydrophobicContact CG2-CG 3.97Å
172G97.8Very high98.4Very high2 Ų22 Ų22%0.0211%0.012CC..Hα-helixtrans-62.9-40.7178.300000112.2V101 G168 I169 A175 L176V101-G172 WeakPolarHBondContact O-CA 3.46Å; G168-G172 PolarHBondContact O-N 3.19Å; I169-G172 PolarHBondContact O-N 3.47Å; G172-A175 VanDerWaalsContact O-CB 3.31Å; G172-A175 WeakPolarHBondContact O-CB 3.17Å; G172-A175 PolarHBondContact O-N 3.43Å; G172-L176 PolarHBondContact O-N 3.2Å
173K98.5Very high98.5Very high1 Ų12 Ų20%0.0041%0.012CC..Hα-helixtrans-65.7-44.1179.6-156.2164.4-165.5124.60112Y102 V149 I169 P170 V171 A175 L176 Y177 Q243 E245 D268 F458Y102-K173 HydrophobicContact CE2-CB 3.97Å; Y102-K173 HydrophobicContact CE2-CG 4.36Å; Y102-K173 PolarHBondContact OH-NZ 2.91Å; V149-K173 HydrophobicContact CG1-CB 4.38Å; V149-K173 HydrophobicContact CG1-CD 4.23Å; I169-K173 WeakPolarHBondContact O-CB 3.31Å; I169-K173 PolarHBondContact O-N 2.95Å; P170-K173 PolarHBondContact O-N 3.44Å; V171-K173 VanDerWaalsContact C-N 3.35Å; V171-K173 PolarHBondContact O-N 3.39Å; K173-A175 VanDerWaalsContact C-N 3.28Å; K173-A175 PolarHBondContact O-N 3.46Å; K173-L176 CarbonylContact O-C 3.54Å; K173-L176 WeakPolarHBondContact O-CA 3.47Å; K173-L176 WeakPolarHBondContact O-CB 3.05Å; K173-L176 PolarHBondContact O-N 2.99Å; K173-Y177 HydrophobicContact CG-CD2 4.48Å; K173-Y177 HydrophobicContact CG-CE2 4.22Å; K173-Y177 VanDerWaalsContact O-CD2 3.29Å; K173-Y177 WeakPolarHBondContact O-CD2 3.46Å; K173-Y177 PolarHBondContact O-N 3.3Å; K173-Q243 VanDerWaalsContact CD-NE2 3.32Å; K173-Q243 VanDerWaalsContact CE-NE2 3.26Å; K173-E245 VanDerWaalsContact CD-CD 3.49Å; K173-E245 HydrophobicContact CD-CG 4.2Å; K173-E245 VanDerWaalsContact CD-OE2 3.22Å; K173-E245 WeakPolarHBondContact CD-OE2 3.33Å; K173-E245 WeakPolarHBondContact CE-OE2 3.37Å; K173-E245 IonicContact NZ-OE1 3.19Å; K173-E245 PolarHBondContact NZ-OE1 3.37Å; K173-E245 IonicContact NZ-OE2 3.05Å; K173-E245 PolarHBondContact NZ-OE2 3.18Å; K173-D268 WeakPolarHBondContact CE-OD2 3.24Å; K173-D268 IonicContact NZ-OD2 3.81Å; K173-D268 PolarHBondContact NZ-OD2 2.98Å; K173-F458 HydrophobicContact CG-CD2 4.46Å; K173-F458 HydrophobicContact CG-CE1 4.34Å; K173-F458 HydrophobicContact CG-CE2 4.03Å; K173-F458 HydrophobicContact CG-CZ 3.98Å
174L98.8Very high98.5Very high8 Ų84.2 Ų4.24%0.0422%0.023CC..Hα-helixtrans-68.5-25.1174.9-71.6172.8000113.3V149 P170 V171 L176 Y177 T178 C188 P190V149-L174 HydrophobicContact CB-CD1 4.35Å; V149-L174 HydrophobicContact CB-CD2 4.37Å; V149-L174 HydrophobicContact CB-CG 4.09Å; V149-L174 HydrophobicContact CG2-CD1 4.44Å; V149-L174 HydrophobicContact CG2-CD2 3.59Å; V149-L174 HydrophobicContact CG2-CG 3.74Å; P170-L174 WeakPolarHBondContact O-CB 3.47Å; P170-L174 WeakPolarHBondContact O-CG 3.35Å; P170-L174 PolarHBondContact O-N 3.36Å; V171-L174 PolarHBondContact O-N 3.47Å; L174-L176 VanDerWaalsContact C-N 3.3Å; L174-Y177 HydrophobicContact CD2-CD1 3.96Å; L174-Y177 HydrophobicContact CD2-CD2 4.26Å; L174-Y177 HydrophobicContact CD2-CE1 4.32Å; L174-Y177 HydrophobicContact CD2-CG 3.94Å; L174-Y177 WeakPolarHBondContact O-CB 3.48Å; L174-Y177 PolarHBondContact O-N 3.18Å; L174-T178 PolarHBondContact O-N 3.47Å; L174-T178 PolarHBondContact O-OG1 2.91Å; L174-C188 HydrophobicContact CB-CB 4.29Å; L174-C188 HydrophobicContact CD1-CB 4.05Å; L174-C188 HydrophobicContact CD2-CB 3.82Å; L174-C188 HydrophobicContact CG-CB 4.27Å; L174-P190 HydrophobicContact CD1-CB 3.82Å; L174-P190 HydrophobicContact CD1-CG 3.9Å
175A98.8Very high98.4Very high0 Ų04.5 Ų4.50%03%0.025CC..Hα-helixtrans-61.7-40.8167.200000111F86 Y87 V171 G172 K173 T178 A179F86-A175 HydrophobicContact CE1-CB 4.16Å; F86-A175 HydrophobicContact CZ-CB 4.23Å; Y87-A175 HydrophobicContact CE1-CB 4.46Å; Y87-A175 WeakPolarHBondContact CE1-O 3.33Å; V171-A175 PolarHBondContact O-N 3Å; G172-A175 VanDerWaalsContact O-CB 3.31Å; G172-A175 WeakPolarHBondContact O-CB 3.17Å; G172-A175 PolarHBondContact O-N 3.43Å; K173-A175 VanDerWaalsContact C-N 3.28Å; K173-A175 PolarHBondContact O-N 3.46Å; A175-T178 PolarHBondContact O-N 2.96Å; A175-A179 WeakPolarHBondContact O-CB 3.42Å; A175-A179 PolarHBondContact O-N 2.68Å
176L98.6Very high98.4Very high1 Ų15.7 Ų5.71%0.0053%0.031CC..Hα-helixtrans-74.6-30.5175.9-60.7-172.8000113.8M98 V101 Y102 G172 K173 L174 T178 A179 C180 G181 S455 F458M98-L176 HydrophobicContact CB-CD2 4.44Å; M98-L176 HydrophobicContact CG-CD1 4Å; M98-L176 HydrophobicContact CG-CD2 3.85Å; M98-L176 HydrophobicContact SD-CD1 4.41Å; V101-L176 HydrophobicContact CG2-CD2 4.12Å; Y102-L176 HydrophobicContact CD1-CD1 3.53Å; Y102-L176 HydrophobicContact CE1-CD1 4.33Å; Y102-L176 HydrophobicContact CG-CD1 3.68Å; Y102-L176 HydrophobicContact CG-CG 4.5Å; G172-L176 PolarHBondContact O-N 3.2Å; K173-L176 CarbonylContact O-C 3.54Å; K173-L176 WeakPolarHBondContact O-CA 3.47Å; K173-L176 WeakPolarHBondContact O-CB 3.05Å; K173-L176 PolarHBondContact O-N 2.99Å; L174-L176 VanDerWaalsContact C-N 3.3Å; L176-T178 PolarHBondContact O-N 2.88Å; L176-A179 PolarHBondContact O-N 3.42Å; L176-C180 WeakPolarHBondContact O-CA 3.4Å; L176-C180 VanDerWaalsContact O-CB 3.22Å; L176-C180 WeakPolarHBondContact O-CB 3.16Å; L176-C180 PolarHBondContact O-N 2.9Å; L176-G181 PolarHBondContact O-N 3.41Å; L176-S455 WeakPolarHBondContact CD1-OG 3.32Å; L176-F458 HydrophobicContact CB-CE2 3.82Å; L176-F458 HydrophobicContact CB-CZ 3.76Å; L176-F458 HydrophobicContact CD1-CZ 4.05Å
177Y98.8Very high98.5Very high1 Ų18.9 Ų8.90%0.0045%0.045CC..Hα-helixtrans-52.9-40168.2-89-128.2000111.3A147 V149 K173 L174 G181 G182 M183 L241 Q243 F458 A462A147-Y177 HydrophobicContact CB-CD1 4.24Å; A147-Y177 HydrophobicContact CB-CE1 4.11Å; V149-Y177 HydrophobicContact CG2-CE2 4.03Å; K173-Y177 HydrophobicContact CG-CD2 4.48Å; K173-Y177 HydrophobicContact CG-CE2 4.22Å; K173-Y177 VanDerWaalsContact O-CD2 3.29Å; K173-Y177 WeakPolarHBondContact O-CD2 3.46Å; K173-Y177 PolarHBondContact O-N 3.3Å; L174-Y177 HydrophobicContact CD2-CD1 3.96Å; L174-Y177 HydrophobicContact CD2-CD2 4.26Å; L174-Y177 HydrophobicContact CD2-CE1 4.32Å; L174-Y177 HydrophobicContact CD2-CG 3.94Å; L174-Y177 WeakPolarHBondContact O-CB 3.48Å; L174-Y177 PolarHBondContact O-N 3.18Å; Y177-G181 CarbonylContact O-C 3.47Å; Y177-G181 VanDerWaalsContact O-C 3.28Å; Y177-G181 WeakPolarHBondContact O-CA 3.38Å; Y177-G181 PolarHBondContact O-N 2.84Å; Y177-G181 VanDerWaalsContact O-N 3.09Å; Y177-G182 PolarHBondContact O-N 3.28Å; Y177-G182 VanDerWaalsContact O-N 3.14Å; Y177-M183 WeakPolarHBondContact O-CB 3.25Å; Y177-M183 PolarHBondContact O-N 3.48Å; Y177-L241 HydrophobicContact CE1-CD2 4.12Å; Y177-Q243 PolarHBondContact OH-OE1 2.9Å; Y177-F458 AromaticContact CD2-CD2 3.35Å; Y177-F458 HydrophobicContact CD2-CD2 3.35Å; Y177-F458 AromaticContact CD2-CE2 3.54Å; Y177-F458 HydrophobicContact CD2-CE2 3.54Å; Y177-F458 HydrophobicContact CE2-CB 4.25Å; Y177-F458 AromaticContact CE2-CD2 3.18Å; Y177-F458 HydrophobicContact CE2-CD2 3.18Å; Y177-F458 AromaticContact CE2-CE2 3.78Å; Y177-F458 HydrophobicContact CE2-CE2 3.78Å; Y177-F458 AromaticContact CE2-CG 3.99Å; Y177-F458 HydrophobicContact CE2-CG 3.99Å; Y177-F458 HydrophobicContact CG-CD2 4.44Å; Y177-A462 HydrophobicContact CD1-CB 3.65Å; Y177-A462 HydrophobicContact CE1-CB 3.18Å
178T98.8Very high98.5Very high0 Ų09.2 Ų9.20%05%0.047CC..Hα-helixtrans-82.9-50.2179.9-56.80000112Y87 L174 A175 L176 G182 M183 P185 R507 Y545Y87-T178 HydrophobicContact CD1-CG2 3.55Å; Y87-T178 HydrophobicContact CD2-CG2 3.74Å; Y87-T178 HydrophobicContact CE1-CG2 3.44Å; Y87-T178 VanDerWaalsContact CE1-CG2 3.44Å; Y87-T178 HydrophobicContact CE2-CG2 3.63Å; Y87-T178 HydrophobicContact CG-CG2 3.7Å; Y87-T178 VanDerWaalsContact CZ-CG2 3.47Å; L174-T178 PolarHBondContact O-N 3.47Å; L174-T178 PolarHBondContact O-OG1 2.91Å; A175-T178 PolarHBondContact O-N 2.96Å; L176-T178 PolarHBondContact O-N 2.88Å; T178-G182 VanDerWaalsContact O-CA 3.24Å; T178-G182 WeakPolarHBondContact O-CA 3.35Å; T178-G182 PolarHBondContact O-N 3.04Å; T178-M183 WeakPolarHBondContact CB-O 3.28Å; T178-M183 VanDerWaalsContact CG2-O 3.32Å; T178-M183 WeakPolarHBondContact CG2-O 3.34Å; T178-M183 PolarHBondContact OG1-O 2.85Å; T178-P185 HydrophobicContact CG2-CB 4.42Å; T178-P185 HydrophobicContact CG2-CG 4.29Å; T178-R507 PolarHBondContact O-NH1 2.85Å; T178-Y545 HydrophobicContact CG2-CD1 3.61Å; T178-Y545 HydrophobicContact CG2-CE1 4.04Å; T178-Y545 HydrophobicContact CG2-CG 4.13Å
179A98.6Very high98.5Very high2 Ų29.2 Ų9.22%0.0175%0.047CC..Hα-helixtrans-67.5-40.8-175.400000112.4Y87 L90 T91 A175 L176 R507Y87-A179 HydrophobicContact CD1-CB 4.23Å; L90-A179 HydrophobicContact CB-CB 4.23Å; L90-A179 HydrophobicContact CD2-CB 4.05Å; T91-A179 HydrophobicContact CG2-CB 4.4Å; A175-A179 WeakPolarHBondContact O-CB 3.42Å; A175-A179 PolarHBondContact O-N 2.68Å; L176-A179 PolarHBondContact O-N 3.42Å; A179-R507 VanDerWaalsContact O-CD 3.29Å; A179-R507 WeakPolarHBondContact O-CD 3.45Å; A179-R507 VanDerWaalsContact O-CG 3.26Å; A179-R507 WeakPolarHBondContact O-CG 3.35Å; A179-R507 PolarHBondContact O-NH1 3.13Å
180C98.5Very high98.6Very high0 Ų09.4 Ų9.40%05%0.049CC..THydrogen-bonded Turntrans-95.5-40.3-179.4-55.90000112L176 P459 I506 R507 S510L176-C180 WeakPolarHBondContact O-CA 3.4Å; L176-C180 VanDerWaalsContact O-CB 3.22Å; L176-C180 WeakPolarHBondContact O-CB 3.16Å; L176-C180 PolarHBondContact O-N 2.9Å; C180-P459 HydrophobicContact CB-CB 3.88Å; C180-P459 HydrophobicContact CB-CG 3.69Å; C180-I506 HydrophobicContact CB-CG1 3.86Å; C180-I506 HydrophobicContact CB-CG2 3.98Å; C180-R507 VanDerWaalsContact O-CA 3.29Å; C180-R507 WeakPolarHBondContact O-CA 3.4Å; C180-R507 WeakPolarHBondContact O-CG 3.42Å; C180-S510 WeakPolarHBondContact O-CB 3.44Å; C180-S510 PolarHBondContact O-OG 3.31Å; C180-S510 VanDerWaalsContact O-OG 3.11Å
181G98.2Very high98.6Very high0 Ų09.4 Ų9.40%05%0.049CC..THydrogen-bonded Turntrans-96.4-13.9-174.600000114.9L176 Y177 M183 P459 L463L176-G181 PolarHBondContact O-N 3.41Å; Y177-G181 CarbonylContact O-C 3.47Å; Y177-G181 VanDerWaalsContact O-C 3.28Å; Y177-G181 WeakPolarHBondContact O-CA 3.38Å; Y177-G181 PolarHBondContact O-N 2.84Å; Y177-G181 VanDerWaalsContact O-N 3.09Å; G181-M183 PolarHBondContact O-N 3.19Å; G181-P459 VanDerWaalsContact N-CB 3.31Å; G181-L463 VanDerWaalsContact O-CD2 3.3Å; G181-L463 WeakPolarHBondContact O-CD2 3.37Å
182G98.5Very high98.6Very high0 Ų09.1 Ų9.10%05%0.047CC..  trans6722.2-173.600000113.7Y177 T178 M544 Y545Y177-G182 PolarHBondContact O-N 3.28Å; Y177-G182 VanDerWaalsContact O-N 3.14Å; T178-G182 VanDerWaalsContact O-CA 3.24Å; T178-G182 WeakPolarHBondContact O-CA 3.35Å; T178-G182 PolarHBondContact O-N 3.04Å; G182-M544 CarbonylContact O-C 3.43Å; G182-M544 WeakPolarHBondContact O-CA 3.47Å; G182-Y545 WeakPolarHBondContact O-CB 3.36Å; G182-Y545 PolarHBondContact O-N 3.2Å
183M98.8Very high98.7Very high9 Ų99 Ų94%0.0445%0.046CC..  trans-61.3146.4168.1-163.559.867.200110.1Y177 T178 G181 C188 A462 V466 Y545Y177-M183 WeakPolarHBondContact O-CB 3.25Å; Y177-M183 PolarHBondContact O-N 3.48Å; T178-M183 WeakPolarHBondContact CB-O 3.28Å; T178-M183 VanDerWaalsContact CG2-O 3.32Å; T178-M183 WeakPolarHBondContact CG2-O 3.34Å; T178-M183 PolarHBondContact OG1-O 2.85Å; G181-M183 PolarHBondContact O-N 3.19Å; M183-C188 VanDerWaalsContact CG-SG 3.51Å; M183-A462 VanDerWaalsContact CE-C 3.45Å; M183-A462 HydrophobicContact CE-CB 3.93Å; M183-A462 WeakPolarHBondContact CE-O 3.35Å; M183-V466 HydrophobicContact CE-CB 3.96Å; M183-V466 HydrophobicContact CE-CG1 4.4Å; M183-V466 HydrophobicContact CE-CG2 3.84Å; M183-V466 HydrophobicContact SD-CB 4.33Å; M183-V466 HydrophobicContact SD-CG1 4.1Å; M183-V466 HydrophobicContact SD-CG2 4.36Å; M183-Y545 WeakPolarHBondContact O-CB 3.42Å
184N98.6Very high98.7Very high46 Ų469.5 Ų9.525%0.2465%0.048CC..  trans-76.1121.5174.6-177.8-26.9000109.5Q186 K187 C188N184-Q186 VanDerWaalsContact C-N 3.28Å; N184-Q186 PolarHBondContact O-N 3.35Å; N184-Q186 PolarHBondContact OD1-N 3.17Å; N184-K187 HydrophobicContact CB-CB 4.46Å; N184-K187 HydrophobicContact CB-CD 4.12Å; N184-K187 HydrophobicContact CB-CG 4.12Å; N184-K187 WeakPolarHBondContact O-CB 3.42Å; N184-K187 PolarHBondContact O-N 3.44Å; N184-C188 PolarHBondContact O-SG 2.99Å
185P98.5Very high98.7Very high11 Ų119.1 Ų9.17%0.0715%0.046CC..G310 helixtrans-64.1-27.1-174.327.2-36.9000114.1E83 Y87 T178 K187 C188 Y545E83-P185 HydrophobicContact CG-CB 4.46Å; E83-P185 HydrophobicContact CG-CG 3.97Å; E83-P185 WeakPolarHBondContact OE1-CB 3.49Å; E83-P185 WeakPolarHBondContact OE2-CG 3.2Å; Y87-P185 HydrophobicContact CD2-CG 4.39Å; Y87-P185 HydrophobicContact CE2-CB 3.7Å; Y87-P185 HydrophobicContact CE2-CG 3.74Å; T178-P185 HydrophobicContact CG2-CB 4.42Å; T178-P185 HydrophobicContact CG2-CG 4.29Å; P185-K187 PolarHBondContact O-N 2.98Å; P185-C188 WeakPolarHBondContact O-CB 3.45Å; P185-C188 PolarHBondContact O-N 3.02Å; P185-Y545 HydrophobicContact CG-CD2 4.39Å; P185-Y545 HydrophobicContact CG-CE2 4Å
186Q98.1Very high98.7Very high27 Ų279.1 Ų9.113%0.1265%0.046CC..G310 helixtrans-70.8-17.2174.2-75161.265.600112.9R9 H23 E142 N184 C188R9-Q186 VanDerWaalsContact CZ-OE1 3.24Å; R9-Q186 VanDerWaalsContact NH1-NE2 3.1Å; H23-Q186 HydrophobicContact CB-CG 4.45Å; H23-Q186 WeakPolarHBondContact ND1-CG 3.35Å; E142-Q186 WeakPolarHBondContact CB-O 3.5Å; E142-Q186 HydrophobicContact CG-CB 4.28Å; N184-Q186 VanDerWaalsContact C-N 3.28Å; N184-Q186 PolarHBondContact O-N 3.35Å; N184-Q186 PolarHBondContact OD1-N 3.17Å; Q186-C188 VanDerWaalsContact C-N 3.32Å
187K98.7Very high98.7Very high66 Ų669 Ų929%0.2875%0.046SC..G310 helixtrans-94.47.7175.1-57-175.6178.9172.70112.5V144 K146 A147 N184 P185V144-K187 WeakPolarHBondContact O-CA 3.1Å; K146-K187 HydrophobicContact CB-CB 4.2Å; K146-K187 HydrophobicContact CD-CD 4Å; K146-K187 HydrophobicContact CG-CB 4.3Å; K146-K187 HydrophobicContact CG-CD 4.1Å; K146-K187 PolarHBondContact N-O 3.35Å; A147-K187 PolarHBondContact N-O 2.91Å; N184-K187 HydrophobicContact CB-CB 4.46Å; N184-K187 HydrophobicContact CB-CD 4.12Å; N184-K187 HydrophobicContact CB-CG 4.12Å; N184-K187 WeakPolarHBondContact O-CB 3.42Å; N184-K187 PolarHBondContact O-N 3.44Å; P185-K187 PolarHBondContact O-N 2.98Å
188C98.8Very high98.7Very high8 Ų812.7 Ų12.75%0.0546%0.063CC..EExtended strand (participates in β ladder)trans-110.1133.8-178.1-67.20000110A147 L174 M183 N184 P185 Q186A147-C188 CarbonylContact O-C 3.55Å; A147-C188 VanDerWaalsContact O-CA 3.27Å; A147-C188 WeakPolarHBondContact O-CA 3.26Å; L174-C188 HydrophobicContact CB-CB 4.29Å; L174-C188 HydrophobicContact CD1-CB 4.05Å; L174-C188 HydrophobicContact CD2-CB 3.82Å; L174-C188 HydrophobicContact CG-CB 4.27Å; M183-C188 VanDerWaalsContact CG-SG 3.51Å; N184-C188 PolarHBondContact O-SG 2.99Å; P185-C188 WeakPolarHBondContact O-CB 3.45Å; P185-C188 PolarHBondContact O-N 3.02Å; Q186-C188 VanDerWaalsContact C-N 3.32Å
189L98.9Very high98.7Very high0 Ų014.4 Ų14.40%07%0.072CC..EExtended strand (participates in β ladder)trans-129.3109.5179.8170.761.1000110.6L123 L137 W140 I145 A147 I148 V149 V191 Y236L123-L189 HydrophobicContact CB-CD1 4.06Å; L137-L189 HydrophobicContact CD2-CD2 4.47Å; W140-L189 HydrophobicContact CD2-CD1 3.46Å; W140-L189 VanDerWaalsContact CD2-CD1 3.46Å; W140-L189 HydrophobicContact CE3-CD1 3.71Å; W140-L189 HydrophobicContact CG-CD1 3.95Å; W140-L189 HydrophobicContact CH2-CD1 4.06Å; W140-L189 HydrophobicContact CZ2-CD1 3.84Å; W140-L189 HydrophobicContact CZ3-CD1 4Å; I145-L189 HydrophobicContact CD1-CB 4.12Å; I145-L189 HydrophobicContact CG1-CB 4.2Å; I145-L189 HydrophobicContact CG1-CD2 4.36Å; I145-L189 HydrophobicContact CG2-CB 3.71Å; I145-L189 HydrophobicContact CG2-CD2 4.45Å; A147-L189 PolarHBondContact O-N 2.89Å; I148-L189 WeakPolarHBondContact CA-O 3.41Å; I148-L189 HydrophobicContact CD1-CD2 4.17Å; I148-L189 HydrophobicContact CG1-CB 3.82Å; I148-L189 HydrophobicContact CG1-CD2 4.1Å; I148-L189 HydrophobicContact CG1-CG 4.15Å; V149-L189 PolarHBondContact N-O 3.38Å; L189-V191 HydrophobicContact CD1-CG2 4.45Å; L189-V191 HydrophobicContact CD2-CG2 4.26Å; L189-V191 HydrophobicContact CG-CG2 3.85Å; L189-Y236 HydrophobicContact CD2-CE2 3.97Å
190P98.9Very high98.7Very high9 Ų918.3 Ų18.36%0.0589%0.09CC..EExtended strand (participates in β ladder)trans-77.4134.8171.612.1-3.1000110.5G122 L123 M167 P170 V171 L174G122-P190 CarbonylContact C-O 3.55Å; G122-P190 WeakPolarHBondContact CA-O 3.01Å; L123-P190 PolarHBondContact N-O 3.01Å; M167-P190 HydrophobicContact SD-CB 4.1Å; P170-P190 HydrophobicContact CB-CB 3.59Å; V171-P190 HydrophobicContact CG2-CB 3.94Å; V171-P190 HydrophobicContact CG2-CG 3.97Å; L174-P190 HydrophobicContact CD1-CB 3.82Å; L174-P190 HydrophobicContact CD1-CG 3.9Å
191V98.9Very high98.7Very high0 Ų025.7 Ų25.70%013%0.125CC..EExtended strand (participates in β ladder)trans-132137.6-178.9-177.40000111.3L123 I125 I148 V149 V150 T151 P170 L189 L193 F228L123-V191 HydrophobicContact CB-CG2 4.5Å; L123-V191 WeakPolarHBondContact O-CA 3.29Å; I125-V191 HydrophobicContact CD1-CG1 3.82Å; I125-V191 HydrophobicContact CG1-CG1 4.28Å; I148-V191 HydrophobicContact CG2-CB 4.45Å; I148-V191 HydrophobicContact CG2-CG2 3.88Å; V149-V191 PolarHBondContact O-N 2.9Å; V150-V191 WeakPolarHBondContact CA-O 3.46Å; V150-V191 HydrophobicContact CB-CB 4.15Å; V150-V191 HydrophobicContact CG2-CB 3.97Å; V150-V191 HydrophobicContact CG2-CG1 3.9Å; T151-V191 PolarHBondContact N-O 3.5Å; P170-V191 WeakPolarHBondContact CG-O 3.38Å; L189-V191 HydrophobicContact CD1-CG2 4.45Å; L189-V191 HydrophobicContact CD2-CG2 4.26Å; L189-V191 HydrophobicContact CG-CG2 3.85Å; V191-L193 HydrophobicContact CG1-CD2 3.99Å; V191-F228 HydrophobicContact CG1-CE2 3.92Å; V191-F228 HydrophobicContact CG1-CZ 4.31Å; V191-F228 HydrophobicContact CG2-CE2 4.5Å
192I98.9Very high98.7Very high0 Ų026.4 Ų26.40%013%0.128CC..EExtended strand (participates in β ladder)trans-114.6131.9164.9-173.368.8000109.2L123 F124 I125 T151 M167L123-I192 PolarHBondContact O-N 2.82Å; F124-I192 HydrophobicContact CB-CG2 4.01Å; F124-I192 HydrophobicContact CD1-CG2 3.18Å; F124-I192 HydrophobicContact CE1-CG2 3.73Å; F124-I192 HydrophobicContact CG-CG2 3.74Å; I125-I192 PolarHBondContact N-O 2.88Å; T151-I192 HydrophobicContact CG2-CD1 3.49Å; T151-I192 VanDerWaalsContact CG2-CD1 3.49Å; T151-I192 WeakPolarHBondContact O-CA 3.4Å; M167-I192 HydrophobicContact CB-CB 4.28Å; M167-I192 HydrophobicContact CB-CG2 4.37Å; M167-I192 HydrophobicContact CE-CB 3.78Å; M167-I192 HydrophobicContact CE-CG2 3.46Å; M167-I192 VanDerWaalsContact CE-CG2 3.46Å
193L98.9Very high98.7Very high0 Ų027.9 Ų27.90%014%0.136CC..EExtended strand (participates in β ladder)trans-99.797.9173-61.1-175.7000109.1I125 V150 T151 D152 V191 V195 F224 L225 F228I125-L193 HydrophobicContact CB-CD2 3.97Å; I125-L193 HydrophobicContact CD1-CD2 4.34Å; I125-L193 HydrophobicContact CG2-CD2 4.48Å; I125-L193 CarbonylContact O-C 3.53Å; I125-L193 VanDerWaalsContact O-CA 3.3Å; I125-L193 WeakPolarHBondContact O-CA 3.5Å; V150-L193 HydrophobicContact CG2-CD1 3.78Å; V150-L193 HydrophobicContact CG2-CD2 4.25Å; V150-L193 HydrophobicContact CG2-CG 3.61Å; T151-L193 PolarHBondContact O-N 3.39Å; D152-L193 WeakPolarHBondContact CA-O 3.45Å; D152-L193 HydrophobicContact CB-CB 4.29Å; V191-L193 HydrophobicContact CG1-CD2 3.99Å; L193-V195 PolarHBondContact O-N 3.47Å; L193-F224 HydrophobicContact CB-CE1 4.16Å; L193-F224 HydrophobicContact CD1-CE1 4.5Å; L193-F224 HydrophobicContact CD2-CE1 4.19Å; L193-F224 HydrophobicContact CD2-CZ 4.18Å; L193-L225 HydrophobicContact CD1-CD1 3.48Å; L193-L225 VanDerWaalsContact CD1-CD1 3.48Å; L193-L225 HydrophobicContact CD1-CD2 3.99Å; L193-L225 HydrophobicContact CD1-CG 4.41Å; L193-F228 HydrophobicContact CD2-CD2 4.01Å; L193-F228 HydrophobicContact CD2-CE2 4.29Å; L193-F228 HydrophobicContact CD2-CG 4.36Å
194D98.9Very high98.7Very high11 Ų1134.8 Ų34.86%0.05917%0.166CC..EExtended strand (participates in β ladder)trans-88.3100.7-178.2-167.5-9.5000110.7I125 S126 I127 C164 G196 G210 L211I125-D194 PolarHBondContact O-N 3.08Å; S126-D194 CarbonylContact C-O 3.18Å; S126-D194 VanDerWaalsContact CA-O 3.23Å; S126-D194 WeakPolarHBondContact CA-O 3.46Å; I127-D194 PolarHBondContact N-O 3.07Å; C164-D194 WeakPolarHBondContact CB-OD2 3.46Å; D194-G196 PolarHBondContact OD1-N 3.47Å; D194-G210 WeakPolarHBondContact OD2-CA 3.39Å; D194-L211 WeakPolarHBondContact O-CD1 3.19Å; D194-L211 PolarHBondContact OD2-N 2.78Å
195V98.9Very high98.7Very high0 Ų035.1 Ų35.10%017%0.168CC..  trans-104.712.4175.9-570000112.1I127 L193 R215 V216 Y221 F224I127-V195 HydrophobicContact CB-CB 4.32Å; I127-V195 HydrophobicContact CB-CG1 4.12Å; I127-V195 HydrophobicContact CD1-CG1 4.4Å; L193-V195 PolarHBondContact O-N 3.47Å; V195-R215 HydrophobicContact CG2-CB 4.39Å; V195-R215 HydrophobicContact CG2-CG 4.27Å; V195-R215 CarbonylContact O-C 3.51Å; V195-R215 VanDerWaalsContact O-CA 3.26Å; V195-R215 WeakPolarHBondContact O-CA 3.33Å; V195-V216 HydrophobicContact CB-CB 4.5Å; V195-V216 PolarHBondContact O-N 2.97Å; V195-Y221 HydrophobicContact CB-CD2 4.28Å; V195-Y221 HydrophobicContact CG1-CD2 3.9Å; V195-Y221 HydrophobicContact CG1-CE2 4.09Å; V195-Y221 HydrophobicContact CG2-CD2 3.98Å; V195-Y221 HydrophobicContact CG2-CE2 3.91Å; V195-F224 HydrophobicContact CG1-CD1 4Å; V195-F224 HydrophobicContact CG1-CE1 3.86Å
196G98.8Very high98.7Very high0 Ų039.9 Ų39.90%020%0.199CC..  trans101.9-175.8-167.300000113.1D194 Q213 R215D194-G196 PolarHBondContact OD1-N 3.47Å; G196-Q213 CarbonylContact C-O 3.55Å; G196-Q213 VanDerWaalsContact CA-O 3.23Å; G196-Q213 WeakPolarHBondContact CA-O 3.48Å; G196-R215 VanDerWaalsContact O-CG 3.28Å; G196-R215 WeakPolarHBondContact O-CG 3.3Å
197T98.8Very high98.7Very high0 Ų043.1 Ų43.10%022%0.216CC..  trans-144.8147.3177.7-177.50000111D161 N199 L202 L203 Y208 Q213D161-T197 PolarHBondContact OD1-OG1 3.09Å; D161-T197 PolarHBondContact OD2-OG1 2.96Å; T197-N199 VanDerWaalsContact C-N 3.33Å; T197-N199 WeakPolarHBondContact OG1-CB 3.46Å; T197-N199 PolarHBondContact OG1-N 3.46Å; T197-N199 VanDerWaalsContact OG1-N 3.14Å; T197-L202 HydrophobicContact CG2-CB 4.25Å; T197-L203 HydrophobicContact CG2-CD2 3.87Å; T197-L203 HydrophobicContact CG2-CG 4.09Å; T197-Y208 HydrophobicContact CG2-CE1 3.93Å; T197-Q213 PolarHBondContact N-O 2.76Å
198E98.7Very high98.7Very high78 Ų7840.4 Ų40.436%0.36420%0.204SC..  trans-90.1-0.9171-63.8-52.9139.800112.9D161 E200 R214 R215D161-E198 PolarHBondContact OD2-N 2.62Å; E198-E200 PolarHBondContact O-N 2.93Å; E198-R214 PolarHBondContact O-NH1 3.39Å; E198-R214 WeakPolarHBondContact OE1-CB 3.16Å; E198-R214 WeakPolarHBondContact OE2-CD 3.43Å; E198-R214 IonicContact OE2-CZ 3.03Å; E198-R214 IonicContact OE2-NE 3.97Å; E198-R214 IonicContact OE2-NH1 2.75Å; E198-R214 PolarHBondContact OE2-NH1 2.63Å; E198-R214 VanDerWaalsContact OE2-NH1 3.16Å; E198-R215 HydrophobicContact CG-CB 4.43Å; E198-R215 HydrophobicContact CG-CG 4.29Å; E198-R215 PolarHBondContact OE1-N 3.32Å
199N98.6Very high98.6Very high36 Ų3643 Ų4319%0.19322%0.217CC..  trans-77.6105.3-180-171.2-33.5000111.3D161 T197 E201 L202 L203D161-N199 WeakPolarHBondContact O-CB 3.25Å; D161-N199 PolarHBondContact O-ND2 3.03Å; T197-N199 VanDerWaalsContact C-N 3.33Å; T197-N199 WeakPolarHBondContact OG1-CB 3.46Å; T197-N199 PolarHBondContact OG1-N 3.46Å; T197-N199 VanDerWaalsContact OG1-N 3.14Å; N199-E201 PolarHBondContact O-N 2.95Å; N199-E201 WeakPolarHBondContact OD1-CB 3.36Å; N199-E201 PolarHBondContact OD1-N 2.91Å; N199-L202 HydrophobicContact CB-CB 4.18Å; N199-L202 HydrophobicContact CB-CD1 3.99Å; N199-L202 HydrophobicContact CB-CG 4.06Å; N199-L202 PolarHBondContact O-N 3.49Å; N199-L202 PolarHBondContact OD1-N 2.86Å; N199-L203 WeakPolarHBondContact O-CG 3.47Å; N199-L203 PolarHBondContact O-N 2.96Å
200E98.6Very high98.6Very high83 Ų8343.7 Ų43.739%0.38822%0.224SC..Hα-helixtrans-55.7-34.4178.6-60.9-60.6156.400114.1E198 K204 R214E198-E200 PolarHBondContact O-N 2.93Å; E200-K204 WeakPolarHBondContact O-CB 3.35Å; E200-K204 WeakPolarHBondContact O-CD 3.37Å; E200-K204 VanDerWaalsContact O-CG 3.25Å; E200-K204 WeakPolarHBondContact O-CG 3.44Å; E200-K204 PolarHBondContact O-N 3.46Å; E200-R214 IonicContact OE1-CZ 2.66Å; E200-R214 IonicContact OE1-NH1 2.71Å; E200-R214 PolarHBondContact OE1-NH1 3.27Å; E200-R214 IonicContact OE1-NH2 3.53Å; E200-R214 PolarHBondContact OE1-NH2 2.82Å; E200-R214 IonicContact OE2-CZ 2.77Å; E200-R214 IonicContact OE2-NH2 3.58Å; E200-R214 PolarHBondContact OE2-NH2 3.23Å
201E98.4Very high98.6Very high156 Ų15645.1 Ų45.173%0.72923%0.231SC*.Hα-helixtrans-68.6-45.1-178.8-59.3-175165.400109.5N199 K204 D205N199-E201 PolarHBondContact O-N 2.95Å; N199-E201 WeakPolarHBondContact OD1-CB 3.36Å; N199-E201 PolarHBondContact OD1-N 2.91Å; E201-K204 PolarHBondContact O-N 3.36Å; E201-D205 WeakPolarHBondContact O-CB 3.14Å; E201-D205 PolarHBondContact O-N 3.04Å
202L98.6Very high98.6Very high14 Ų1450.5 Ų50.57%0.07325%0.251CS..Hα-helixtrans-66.3-39.7176.5-64-177.8000112.5L162 T197 N199 K204 D205 Y208L162-L202 VanDerWaalsContact C-CD1 3.5Å; L162-L202 VanDerWaalsContact O-CD1 3.32Å; L162-L202 WeakPolarHBondContact O-CD1 3.36Å; T197-L202 HydrophobicContact CG2-CB 4.25Å; N199-L202 HydrophobicContact CB-CB 4.18Å; N199-L202 HydrophobicContact CB-CD1 3.99Å; N199-L202 HydrophobicContact CB-CG 4.06Å; N199-L202 PolarHBondContact O-N 3.49Å; N199-L202 PolarHBondContact OD1-N 2.86Å; L202-K204 PolarHBondContact O-N 3.04Å; L202-D205 PolarHBondContact O-N 3.13Å; L202-Y208 HydrophobicContact CB-CD1 4.3Å; L202-Y208 HydrophobicContact CB-CD2 3.98Å; L202-Y208 HydrophobicContact CB-CE1 4.46Å; L202-Y208 HydrophobicContact CB-CE2 4.17Å; L202-Y208 HydrophobicContact CB-CG 4.06Å; L202-Y208 HydrophobicContact CD1-CD2 4.34Å; L202-Y208 HydrophobicContact CD1-CE2 3.97Å; L202-Y208 HydrophobicContact CD2-CD2 4.03Å; L202-Y208 HydrophobicContact CD2-CE2 4.47Å; L202-Y208 HydrophobicContact CG-CD2 4.34Å; L202-Y208 HydrophobicContact CG-CE2 4.44Å; L202-Y208 WeakPolarHBondContact O-CB 3.46Å; L202-Y208 WeakPolarHBondContact O-CD1 3.16Å
203L98.6Very high98.6Very high32 Ų3253.5 Ų53.517%0.16827%0.265CS..Hα-helixtrans-59.7-34.7176.1-69.6175000112T197 N199 R212 R214T197-L203 HydrophobicContact CG2-CD2 3.87Å; T197-L203 HydrophobicContact CG2-CG 4.09Å; N199-L203 WeakPolarHBondContact O-CG 3.47Å; N199-L203 PolarHBondContact O-N 2.96Å; L203-R212 PolarHBondContact O-NH1 3.49Å; L203-R212 VanDerWaalsContact O-NH1 3.17Å; L203-R214 VanDerWaalsContact CD1-CZ 3.41Å
204K98.6Very high98.6Very high153 Ų15358.4 Ų58.467%0.66528%0.283SS*.Hα-helixtrans-89.3-24.8-179.5-67.6168.8-169.4166.40113.8E200 E201 L202 P206E200-K204 WeakPolarHBondContact O-CB 3.35Å; E200-K204 WeakPolarHBondContact O-CD 3.37Å; E200-K204 VanDerWaalsContact O-CG 3.25Å; E200-K204 WeakPolarHBondContact O-CG 3.44Å; E200-K204 PolarHBondContact O-N 3.46Å; E201-K204 PolarHBondContact O-N 3.36Å; L202-K204 PolarHBondContact O-N 3.04Å; K204-P206 WeakPolarHBondContact O-CD 3.31Å
205D98.4Very high98.6Very high53 Ų5358.4 Ų58.428%0.28328%0.283SS..  trans-69.1112.8-176.9176.9-0.7000110.6E201 L202 L207 Y208 R212E201-D205 WeakPolarHBondContact O-CB 3.14Å; E201-D205 PolarHBondContact O-N 3.04Å; L202-D205 PolarHBondContact O-N 3.13Å; D205-L207 PolarHBondContact O-N 3.26Å; D205-L207 WeakPolarHBondContact OD1-CB 3.21Å; D205-L207 PolarHBondContact OD1-N 3.05Å; D205-Y208 WeakPolarHBondContact O-CB 3.19Å; D205-Y208 PolarHBondContact O-N 3.3Å; D205-R212 PolarHBondContact O-NH1 2.8Å; D205-R212 PolarHBondContact O-NH2 3Å
206P98.1Very high98.6Very high112 Ų11259.5 Ų59.573%0.72729%0.289SS*.THydrogen-bonded Turntrans-62.1-15.3-17828.6-37.1000114.4K204 R212K204-P206 WeakPolarHBondContact O-CD 3.31Å; P206-R212 PolarHBondContact O-NH2 3.31Å; P206-R212 VanDerWaalsContact O-NH2 3.07Å
207L98.4Very high98.6Very high94 Ų9464 Ų6449%0.49231%0.306SS..THydrogen-bonded Turntrans-88.1-13.1175.8-59.3-178.3000113.2S114 L115 D205 I209S114-L207 WeakPolarHBondContact CB-O 3.44Å; L115-L207 HydrophobicContact CD1-CD1 3.86Å; D205-L207 PolarHBondContact O-N 3.26Å; D205-L207 WeakPolarHBondContact OD1-CB 3.21Å; D205-L207 PolarHBondContact OD1-N 3.05Å; L207-I209 WeakPolarHBondContact O-CG2 3.4Å; L207-I209 PolarHBondContact O-N 3.47Å
208Y98.6Very high98.5Very high9 Ų966.2 Ų66.24%0.03533%0.329CS..  trans-53.5123.5179.8-178.4-125.2000112S114 C164 T197 L202 D205 G210 R212S114-Y208 WeakPolarHBondContact OG-CA 3.45Å; C164-Y208 HydrophobicContact CB-CE2 4.26Å; C164-Y208 PolarHBondContact N-OH 3.43Å; T197-Y208 HydrophobicContact CG2-CE1 3.93Å; L202-Y208 HydrophobicContact CB-CD1 4.3Å; L202-Y208 HydrophobicContact CB-CD2 3.98Å; L202-Y208 HydrophobicContact CB-CE1 4.46Å; L202-Y208 HydrophobicContact CB-CE2 4.17Å; L202-Y208 HydrophobicContact CB-CG 4.06Å; L202-Y208 HydrophobicContact CD1-CD2 4.34Å; L202-Y208 HydrophobicContact CD1-CE2 3.97Å; L202-Y208 HydrophobicContact CD2-CD2 4.03Å; L202-Y208 HydrophobicContact CD2-CE2 4.47Å; L202-Y208 HydrophobicContact CG-CD2 4.34Å; L202-Y208 HydrophobicContact CG-CE2 4.44Å; L202-Y208 WeakPolarHBondContact O-CB 3.46Å; L202-Y208 WeakPolarHBondContact O-CD1 3.16Å; D205-Y208 WeakPolarHBondContact O-CB 3.19Å; D205-Y208 PolarHBondContact O-N 3.3Å; Y208-G210 VanDerWaalsContact CE1-C 3.48Å; Y208-R212 HydrophobicContact CD1-CG 4.17Å; Y208-R212 PolarHBondContact O-NH2 2.88Å
209I98.1Very high98.4Very high64 Ų6466.7 Ų66.733%0.32834%0.341SS..  trans-89.6-12.5-173.264.3174.8000114.1Y113 S114 F117 L207Y113-I209 HydrophobicContact CD1-CD1 3.94Å; Y113-I209 HydrophobicContact CE1-CD1 4.3Å; S114-I209 PolarHBondContact OG-N 2.91Å; F117-I209 HydrophobicContact CD2-CD1 3.83Å; F117-I209 HydrophobicContact CE2-CD1 4.23Å; F117-I209 HydrophobicContact CG-CD1 4.4Å; L207-I209 WeakPolarHBondContact O-CG2 3.4Å; L207-I209 PolarHBondContact O-N 3.47Å
210G98.6Very high98.4Very high13 Ų1369.6 Ų69.613%0.13435%0.353CS..SBendtrans-89.2-176.4179.800000113.9C164 D194 Y208 R212C164-G210 VanDerWaalsContact CB-CA 3.41Å; D194-G210 WeakPolarHBondContact OD2-CA 3.39Å; Y208-G210 VanDerWaalsContact CE1-C 3.48Å; G210-R212 PolarHBondContact O-N 3.15Å
211L98.8Very high98.5Very high39 Ų3965.8 Ų65.820%0.20434%0.335CS..  trans-64.4120.4176.5-64.6-178.7000111.2I127 D194 Q213I127-L211 HydrophobicContact CG2-CD1 3.95Å; D194-L211 WeakPolarHBondContact O-CD1 3.19Å; D194-L211 PolarHBondContact OD2-N 2.78Å; L211-Q213 HydrophobicContact CB-CG 3.99Å; L211-Q213 PolarHBondContact O-N 3.01Å
212R98.7Very high98.5Very high114 Ų11460.3 Ų60.343%0.4331%0.311SS..SBendtrans-79.757.9175.9-67.5178.5-172.7-78.8-9.9112.1L203 D205 P206 Y208 G210L203-R212 PolarHBondContact O-NH1 3.49Å; L203-R212 VanDerWaalsContact O-NH1 3.17Å; D205-R212 PolarHBondContact O-NH1 2.8Å; D205-R212 PolarHBondContact O-NH2 3Å; P206-R212 PolarHBondContact O-NH2 3.31Å; P206-R212 VanDerWaalsContact O-NH2 3.07Å; Y208-R212 HydrophobicContact CD1-CG 4.17Å; Y208-R212 PolarHBondContact O-NH2 2.88Å; G210-R212 PolarHBondContact O-N 3.15Å
213Q98.8Very high98.5Very high63 Ų6362.9 Ų62.929%0.29433%0.325SS..SBendtrans-144.2163.5176.165.5-179.875.900110.4H128 G196 T197 L211H128-Q213 PolarHBondContact CE1-OE1 2.94Å; H128-Q213 PolarHBondContact NE2-OE1 3.28Å; G196-Q213 CarbonylContact C-O 3.55Å; G196-Q213 VanDerWaalsContact CA-O 3.23Å; G196-Q213 WeakPolarHBondContact CA-O 3.48Å; T197-Q213 PolarHBondContact N-O 2.76Å; L211-Q213 HydrophobicContact CB-CG 3.99Å; L211-Q213 PolarHBondContact O-N 3.01Å
214R98.8Very high98.5Very high102 Ų10261.4 Ų61.439%0.38532%0.317SS..PPolyproline II helixtrans-64.5157.2170.6-61.9-69.9165.51760.1111.3E198 E200 L203 V216E198-R214 PolarHBondContact O-NH1 3.39Å; E198-R214 WeakPolarHBondContact OE1-CB 3.16Å; E198-R214 WeakPolarHBondContact OE2-CD 3.43Å; E198-R214 IonicContact OE2-CZ 3.03Å; E198-R214 IonicContact OE2-NE 3.97Å; E198-R214 IonicContact OE2-NH1 2.75Å; E198-R214 PolarHBondContact OE2-NH1 2.63Å; E198-R214 VanDerWaalsContact OE2-NH1 3.16Å; E200-R214 IonicContact OE1-CZ 2.66Å; E200-R214 IonicContact OE1-NH1 2.71Å; E200-R214 PolarHBondContact OE1-NH1 3.27Å; E200-R214 IonicContact OE1-NH2 3.53Å; E200-R214 PolarHBondContact OE1-NH2 2.82Å; E200-R214 IonicContact OE2-CZ 2.77Å; E200-R214 IonicContact OE2-NH2 3.58Å; E200-R214 PolarHBondContact OE2-NH2 3.23Å; L203-R214 VanDerWaalsContact CD1-CZ 3.41Å; R214-V216 PolarHBondContact O-N 2.86Å
215R98.8Very high98.5Very high12 Ų1254.1 Ų54.15%0.04529%0.285CS..PPolyproline II helixtrans-64.5127.5179.6-74.1-176.6174.5-85.1-4.6110.6D152 G153 E154 D161 V195 G196 E198D152-R215 VanDerWaalsContact O-CZ 3.31Å; D152-R215 PolarHBondContact O-NH1 2.89Å; D152-R215 PolarHBondContact O-NH2 2.82Å; D152-R215 IonicContact OD2-NH1 3.35Å; G153-R215 VanDerWaalsContact C-NH2 3.33Å; G153-R215 PolarHBondContact O-NH2 2.76Å; E154-R215 VanDerWaalsContact CA-NH2 3.32Å; D161-R215 IonicContact OD1-CZ 3.67Å; D161-R215 IonicContact OD1-NE 2.71Å; D161-R215 PolarHBondContact OD1-NE 2.95Å; D161-R215 IonicContact OD1-NH2 3.71Å; D161-R215 PolarHBondContact OD1-NH2 3.25Å; D161-R215 IonicContact OD2-CZ 3.03Å; D161-R215 IonicContact OD2-NE 3.89Å; D161-R215 PolarHBondContact OD2-NE 2.87Å; D161-R215 IonicContact OD2-NH2 3.45Å; V195-R215 HydrophobicContact CG2-CB 4.39Å; V195-R215 HydrophobicContact CG2-CG 4.27Å; V195-R215 CarbonylContact O-C 3.51Å; V195-R215 VanDerWaalsContact O-CA 3.26Å; V195-R215 WeakPolarHBondContact O-CA 3.33Å; G196-R215 VanDerWaalsContact O-CG 3.28Å; G196-R215 WeakPolarHBondContact O-CG 3.3Å; E198-R215 HydrophobicContact CG-CB 4.43Å; E198-R215 HydrophobicContact CG-CG 4.29Å; E198-R215 PolarHBondContact OE1-N 3.32Å
216V98.7Very high98.5Very high22 Ų2253.5 Ų53.513%0.13328%0.282CS..PPolyproline II helixtrans-68.1135.9166.7178.30000109.1I127 V195 R214 E220I127-V216 HydrophobicContact CD1-CG1 4.39Å; I127-V216 HydrophobicContact CG1-CB 4.08Å; I127-V216 HydrophobicContact CG1-CG1 4.11Å; I127-V216 HydrophobicContact CG1-CG2 4.03Å; I127-V216 HydrophobicContact CG2-CG2 4.12Å; V195-V216 HydrophobicContact CB-CB 4.5Å; V195-V216 PolarHBondContact O-N 2.97Å; R214-V216 PolarHBondContact O-N 2.86Å; V216-E220 HydrophobicContact CG1-CB 3.8Å; V216-E220 HydrophobicContact CG1-CG 3.79Å; V216-E220 WeakPolarHBondContact CG1-OE2 3.47Å
217R98.1Very high98.6Very high96 Ų9649.6 Ų49.636%0.36225%0.254SS..  trans-133.6174.2-176-56-60.9-178168.714.6110.9E154E154-R217 IonicContact OE1-CZ 3.86Å; E154-R217 VanDerWaalsContact OE1-CZ 3.31Å; E154-R217 IonicContact OE1-NH1 2.85Å; E154-R217 PolarHBondContact OE1-NH1 3.03Å; E154-R217 IonicContact OE1-NH2 2.74Å; E154-R217 PolarHBondContact OE1-NH2 2.73Å; E154-R217 IonicContact OE2-CZ 3.23Å; E154-R217 IonicContact OE2-NH1 2.77Å; E154-R217 PolarHBondContact OE2-NH1 3.2Å; E154-R217 IonicContact OE2-NH2 2.81Å
218G97.1Very high98.6Very high46 Ų4645.1 Ų45.147%0.47423%0.231SC..THydrogen-bonded Turntrans75.3-151.9176.700000112.5E220 Y221 D222G218-E220 PolarHBondContact O-N 2.91Å; G218-Y221 PolarHBondContact O-N 3.06Å; G218-D222 PolarHBondContact O-N 3.37Å; G218-D222 VanDerWaalsContact O-N 3.11Å
219S98.1Very high98.6Very high88 Ų8844.7 Ų44.762%0.61523%0.229SC*.Hα-helixtrans-58-34.6-175.451.70000113.2Y221 D222 D223S219-Y221 PolarHBondContact O-N 3.12Å; S219-D222 PolarHBondContact O-N 3.45Å; S219-D222 VanDerWaalsContact O-N 3.16Å; S219-D223 WeakPolarHBondContact O-CB 3.35Å; S219-D223 PolarHBondContact O-N 3.09Å
220E98.6Very high98.6Very high97 Ų9747.1 Ų47.145%0.45324%0.239SC..Hα-helixtrans-63.9-42-179.3-169.3178-178.300112.1I127 R130 V216 G218 F224I127-E220 HydrophobicContact CD1-CG 4.35Å; R130-E220 PolarHBondContact NH1-O 2.83Å; V216-E220 HydrophobicContact CG1-CB 3.8Å; V216-E220 HydrophobicContact CG1-CG 3.79Å; V216-E220 WeakPolarHBondContact CG1-OE2 3.47Å; G218-E220 PolarHBondContact O-N 2.91Å; E220-F224 WeakPolarHBondContact O-CB 3.15Å; E220-F224 PolarHBondContact O-N 2.9Å
221Y98.8Very high98.6Very high2 Ų247.3 Ų47.31%0.00824%0.239CC..Hα-helixtrans-65.3-42.9171.5177.9-84.4000111.4D152 V195 G218 S219 F224 L225 F247 L255D152-Y221 PolarHBondContact OD2-OH 3.08Å; V195-Y221 HydrophobicContact CB-CD2 4.28Å; V195-Y221 HydrophobicContact CG1-CD2 3.9Å; V195-Y221 HydrophobicContact CG1-CE2 4.09Å; V195-Y221 HydrophobicContact CG2-CD2 3.98Å; V195-Y221 HydrophobicContact CG2-CE2 3.91Å; G218-Y221 PolarHBondContact O-N 3.06Å; S219-Y221 PolarHBondContact O-N 3.12Å; Y221-F224 PolarHBondContact O-N 2.78Å; Y221-L225 HydrophobicContact CD1-CD2 4.04Å; Y221-L225 HydrophobicContact CD2-CD2 4.28Å; Y221-L225 HydrophobicContact CE1-CD2 3.69Å; Y221-L225 HydrophobicContact CE1-CG 3.99Å; Y221-L225 HydrophobicContact CE2-CD2 3.96Å; Y221-L225 HydrophobicContact CG-CD2 4.33Å; Y221-L225 WeakPolarHBondContact O-CD2 3.45Å; Y221-L225 PolarHBondContact O-N 3.48Å; Y221-F247 WeakPolarHBondContact OH-CD1 3.35Å; Y221-F247 WeakPolarHBondContact OH-CE1 3.31Å; Y221-L255 HydrophobicContact CE1-CD1 4.43Å
222D98.6Very high98.6Very high41 Ų4145.5 Ų45.522%0.21923%0.229CC..Hα-helixtrans-64.8-47-175.4-71.9-12.5000112.8G218 S219 F224 L225 D226 R254G218-D222 PolarHBondContact O-N 3.37Å; G218-D222 VanDerWaalsContact O-N 3.11Å; S219-D222 PolarHBondContact O-N 3.45Å; S219-D222 VanDerWaalsContact O-N 3.16Å; D222-F224 VanDerWaalsContact C-N 3.29Å; D222-F224 PolarHBondContact O-N 3.12Å; D222-L225 PolarHBondContact O-N 3.25Å; D222-D226 PolarHBondContact O-N 3.41Å; D222-R254 IonicContact OD1-CZ 2.67Å; D222-R254 IonicContact OD1-NH1 3.65Å; D222-R254 PolarHBondContact OD1-NH1 3.49Å; D222-R254 IonicContact OD1-NH2 3.85Å; D222-R254 PolarHBondContact OD1-NH2 2.95Å; D222-R254 IonicContact OD2-CZ 2.62Å; D222-R254 IonicContact OD2-NH1 3.93Å; D222-R254 PolarHBondContact OD2-NH1 3.24Å; D222-R254 VanDerWaalsContact OD2-NH1 3.17Å
223D98.8Very high98.6Very high69 Ų6940.7 Ų40.737%0.36921%0.213SC..Hα-helixtrans-68.3-31177.8-61-18000111.4R130 S219 D226 E227R130-D223 VanDerWaalsContact CZ-CB 3.44Å; R130-D223 IonicContact CZ-OD2 2.71Å; R130-D223 IonicContact NH1-OD2 2.72Å; R130-D223 IonicContact NH2-OD2 3.96Å; R130-D223 PolarHBondContact NH2-OD2 3.18Å; S219-D223 WeakPolarHBondContact O-CB 3.35Å; S219-D223 PolarHBondContact O-N 3.09Å; D223-D226 PolarHBondContact O-N 3.47Å; D223-E227 PolarHBondContact O-N 2.52Å
224F98.9Very high98.6Very high0 Ų042.6 Ų42.60%023%0.233CC..Hα-helixtrans-66.2-41.1173.5171.2-113.8000111.4I125 S126 I127 R130 I133 L193 V195 E220 Y221 D222 D226 E227 F228I125-F224 HydrophobicContact CG2-CE2 3.96Å; I125-F224 HydrophobicContact CG2-CZ 3.83Å; S126-F224 WeakPolarHBondContact O-CE2 3.38Å; S126-F224 VanDerWaalsContact O-CZ 3.31Å; S126-F224 WeakPolarHBondContact O-CZ 3.47Å; I127-F224 HydrophobicContact CD1-CB 3.54Å; I127-F224 HydrophobicContact CD1-CD1 3.82Å; I127-F224 HydrophobicContact CD1-CD2 4.1Å; I127-F224 HydrophobicContact CD1-CG 3.55Å; R130-F224 HydrophobicContact CB-CD2 4.25Å; I133-F224 HydrophobicContact CD1-CD2 3.86Å; I133-F224 HydrophobicContact CD1-CE2 3.6Å; I133-F224 HydrophobicContact CD1-CZ 4.43Å; I133-F224 HydrophobicContact CG1-CE2 4.15Å; L193-F224 HydrophobicContact CB-CE1 4.16Å; L193-F224 HydrophobicContact CD1-CE1 4.5Å; L193-F224 HydrophobicContact CD2-CE1 4.19Å; L193-F224 HydrophobicContact CD2-CZ 4.18Å; V195-F224 HydrophobicContact CG1-CD1 4Å; V195-F224 HydrophobicContact CG1-CE1 3.86Å; E220-F224 WeakPolarHBondContact O-CB 3.15Å; E220-F224 PolarHBondContact O-N 2.9Å; Y221-F224 PolarHBondContact O-N 2.78Å; D222-F224 VanDerWaalsContact C-N 3.29Å; D222-F224 PolarHBondContact O-N 3.12Å; F224-D226 VanDerWaalsContact C-N 3.34Å; F224-E227 PolarHBondContact O-N 2.81Å; F224-F228 PolarHBondContact O-N 2.94Å
225L98.9Very high98.6Very high0 Ų040.7 Ų40.70%023%0.228CC..Hα-helixtrans-66.6-35.9172.7-92.5-68.2000111.8L193 Y221 D222 F228 M229 F244 L255L193-L225 HydrophobicContact CD1-CD1 3.48Å; L193-L225 VanDerWaalsContact CD1-CD1 3.48Å; L193-L225 HydrophobicContact CD1-CD2 3.99Å; L193-L225 HydrophobicContact CD1-CG 4.41Å; Y221-L225 HydrophobicContact CD1-CD2 4.04Å; Y221-L225 HydrophobicContact CD2-CD2 4.28Å; Y221-L225 HydrophobicContact CE1-CD2 3.69Å; Y221-L225 HydrophobicContact CE1-CG 3.99Å; Y221-L225 HydrophobicContact CE2-CD2 3.96Å; Y221-L225 HydrophobicContact CG-CD2 4.33Å; Y221-L225 WeakPolarHBondContact O-CD2 3.45Å; Y221-L225 PolarHBondContact O-N 3.48Å; D222-L225 PolarHBondContact O-N 3.25Å; L225-F228 PolarHBondContact O-N 3.01Å; L225-M229 VanDerWaalsContact O-CG 3.28Å; L225-M229 WeakPolarHBondContact O-CG 3.5Å; L225-M229 PolarHBondContact O-N 3.23Å; L225-M229 VanDerWaalsContact O-N 3.08Å; L225-F244 HydrophobicContact CD1-CE1 4.17Å; L225-L255 HydrophobicContact CB-CD2 4.3Å; L225-L255 HydrophobicContact CD1-CD1 4.41Å; L225-L255 HydrophobicContact CG-CD1 4.39Å; L225-L255 HydrophobicContact CG-CD2 4.21Å
226D98.9Very high98.6Very high41 Ų4141.5 Ų41.522%0.21923%0.231CC..Hα-helixtrans-61.1-50.3173.2-75.9-32.4000111.1D222 D223 F224 F228 M229 E230 K258 Y259D222-D226 PolarHBondContact O-N 3.41Å; D223-D226 PolarHBondContact O-N 3.47Å; F224-D226 VanDerWaalsContact C-N 3.34Å; D226-F228 PolarHBondContact O-N 2.7Å; D226-M229 PolarHBondContact O-N 3.15Å; D226-M229 VanDerWaalsContact O-N 3.14Å; D226-E230 WeakPolarHBondContact O-CB 3.49Å; D226-E230 WeakPolarHBondContact O-CG 3.45Å; D226-E230 PolarHBondContact O-N 3.32Å; D226-K258 WeakPolarHBondContact OD1-CE 3.39Å; D226-K258 IonicContact OD1-NZ 3.9Å; D226-K258 PolarHBondContact OD1-NZ 3.21Å; D226-K258 IonicContact OD2-NZ 2.86Å; D226-K258 PolarHBondContact OD2-NZ 3.22Å; D226-Y259 PolarHBondContact N-OH 2.7Å; D226-Y259 VanDerWaalsContact OD1-CE1 3.3Å; D226-Y259 WeakPolarHBondContact OD1-CE1 3.21Å; D226-Y259 PolarHBondContact OD1-OH 3.47Å
227E98.9Very high98.6Very high30 Ų3041.9 Ų41.914%0.1424%0.24CC..Hα-helixtrans-58-38.7176.8-173.6-167.416100111.8R130 G131 H132 I133 D223 F224 S231R130-E227 WeakPolarHBondContact CA-OE2 3.32Å; R130-E227 WeakPolarHBondContact CG-OE2 3.5Å; G131-E227 VanDerWaalsContact C-OE1 3.26Å; G131-E227 VanDerWaalsContact CA-OE1 3.27Å; G131-E227 WeakPolarHBondContact CA-OE1 3.27Å; G131-E227 PolarHBondContact N-OE1 3.43Å; G131-E227 PolarHBondContact N-OE2 3.08Å; H132-E227 PolarHBondContact N-OE1 3.37Å; I133-E227 HydrophobicContact CB-CG 4.33Å; I133-E227 HydrophobicContact CD1-CB 3.96Å; I133-E227 HydrophobicContact CD1-CG 3.82Å; I133-E227 HydrophobicContact CG1-CG 4.2Å; I133-E227 WeakPolarHBondContact CG1-OE1 3.35Å; I133-E227 PolarHBondContact N-OE1 3.28Å; D223-E227 PolarHBondContact O-N 2.52Å; F224-E227 PolarHBondContact O-N 2.81Å; E227-S231 WeakPolarHBondContact O-CB 3.44Å; E227-S231 PolarHBondContact O-N 3.32Å; E227-S231 PolarHBondContact O-OG 3.36Å
228F98.9Very high98.6Very high0 Ų041.6 Ų41.60%024%0.243CC..Hα-helixtrans-60.9-50.6175.9171-101.6000111.5I125 I133 I148 V150 V191 L193 F224 L225 D226 E230 S231 V232 I242I125-F228 HydrophobicContact CD1-CD2 3.86Å; I125-F228 HydrophobicContact CD1-CE2 3.86Å; I133-F228 HydrophobicContact CD1-CB 3.94Å; I133-F228 HydrophobicContact CG2-CD2 4.47Å; I148-F228 HydrophobicContact CG2-CZ 4.29Å; V150-F228 HydrophobicContact CB-CE1 4.32Å; V150-F228 HydrophobicContact CB-CZ 4.13Å; V150-F228 HydrophobicContact CG1-CE1 4.1Å; V150-F228 HydrophobicContact CG1-CZ 4.39Å; V150-F228 HydrophobicContact CG2-CE1 4.15Å; V150-F228 HydrophobicContact CG2-CZ 3.96Å; V191-F228 HydrophobicContact CG1-CE2 3.92Å; V191-F228 HydrophobicContact CG1-CZ 4.31Å; V191-F228 HydrophobicContact CG2-CE2 4.5Å; L193-F228 HydrophobicContact CD2-CD2 4.01Å; L193-F228 HydrophobicContact CD2-CE2 4.29Å; L193-F228 HydrophobicContact CD2-CG 4.36Å; F224-F228 PolarHBondContact O-N 2.94Å; L225-F228 PolarHBondContact O-N 3.01Å; D226-F228 PolarHBondContact O-N 2.7Å; F228-E230 VanDerWaalsContact C-N 3.34Å; F228-E230 PolarHBondContact O-N 3.36Å; F228-S231 PolarHBondContact O-N 3.22Å; F228-V232 HydrophobicContact CD2-CG2 3.95Å; F228-V232 HydrophobicContact CE1-CG2 4.3Å; F228-V232 HydrophobicContact CE2-CG2 3.54Å; F228-V232 HydrophobicContact CG-CG2 4.49Å; F228-V232 HydrophobicContact CZ-CG2 3.75Å; F228-V232 WeakPolarHBondContact O-CB 3.11Å; F228-V232 VanDerWaalsContact O-CG2 3.29Å; F228-V232 WeakPolarHBondContact O-CG2 3.27Å; F228-V232 PolarHBondContact O-N 2.63Å; F228-I242 HydrophobicContact CE1-CG2 4.2Å
229M98.9Very high98.7Very high0 Ų042.6 Ų42.60%024%0.238CC..Hα-helixtrans-62.6-42.1-179.5-64.4-62.6-69.500111.6L225 D226 S233 I242 F244 Y259 Y263 T265L225-M229 VanDerWaalsContact O-CG 3.28Å; L225-M229 WeakPolarHBondContact O-CG 3.5Å; L225-M229 PolarHBondContact O-N 3.23Å; L225-M229 VanDerWaalsContact O-N 3.08Å; D226-M229 PolarHBondContact O-N 3.15Å; D226-M229 VanDerWaalsContact O-N 3.14Å; M229-S233 VanDerWaalsContact O-CB 3.29Å; M229-S233 WeakPolarHBondContact O-CB 3.34Å; M229-S233 PolarHBondContact O-N 2.91Å; M229-S233 VanDerWaalsContact O-N 3.09Å; M229-S233 PolarHBondContact O-OG 2.64Å; M229-I242 HydrophobicContact CE-CB 4.46Å; M229-I242 HydrophobicContact CE-CD1 3.64Å; M229-I242 HydrophobicContact CE-CG2 4.4Å; M229-I242 HydrophobicContact SD-CD1 3.81Å; M229-I242 HydrophobicContact SD-CG2 4.05Å; M229-F244 HydrophobicContact CE-CE2 4.35Å; M229-F244 HydrophobicContact CE-CZ 4.39Å; M229-F244 HydrophobicContact SD-CE2 4.21Å; M229-F244 HydrophobicContact SD-CZ 3.74Å; M229-Y259 HydrophobicContact CE-CD2 4.08Å; M229-Y259 HydrophobicContact CE-CG 3.99Å; M229-Y259 HydrophobicContact CG-CD1 4.28Å; M229-Y259 HydrophobicContact CG-CD2 3.99Å; M229-Y259 HydrophobicContact CG-CE1 4.1Å; M229-Y259 HydrophobicContact CG-CE2 3.76Å; M229-Y259 HydrophobicContact CG-CG 4.26Å; M229-Y259 HydrophobicContact SD-CD2 4.21Å; M229-Y259 HydrophobicContact SD-CE2 4.39Å; M229-Y263 HydrophobicContact CB-CD2 4.21Å; M229-Y263 HydrophobicContact CB-CE1 4.3Å; M229-Y263 HydrophobicContact CB-CE2 3.7Å; M229-Y263 HydrophobicContact CE-CD1 4.28Å; M229-Y263 HydrophobicContact CE-CD2 3.49Å; M229-Y263 VanDerWaalsContact CE-CD2 3.49Å; M229-Y263 HydrophobicContact CE-CE2 4.19Å; M229-Y263 HydrophobicContact CE-CG 3.53Å; M229-Y263 HydrophobicContact CG-CE2 4.43Å; M229-T265 HydrophobicContact CE-CG2 4.47Å
230E98.9Very high98.7Very high114 Ų11438.7 Ų38.753%0.53321%0.211SC..Hα-helixtrans-64.5-48.5176.4-71.5176.2-176.700111.7D226 F228 V232 S233 S234D226-E230 WeakPolarHBondContact O-CB 3.49Å; D226-E230 WeakPolarHBondContact O-CG 3.45Å; D226-E230 PolarHBondContact O-N 3.32Å; F228-E230 VanDerWaalsContact C-N 3.34Å; F228-E230 PolarHBondContact O-N 3.36Å; E230-V232 PolarHBondContact O-N 3.06Å; E230-S233 PolarHBondContact O-N 3.49Å; E230-S233 PolarHBondContact O-OG 3.21Å; E230-S233 VanDerWaalsContact O-OG 3.07Å; E230-S234 WeakPolarHBondContact O-CB 3.39Å; E230-S234 PolarHBondContact O-N 3.2Å
231S98.9Very high98.7Very high18 Ų1834.1 Ų34.113%0.12619%0.189CC..Hα-helixtrans-64.4-43.3-178.1-64.50000112E227 F228 K235E227-S231 WeakPolarHBondContact O-CB 3.44Å; E227-S231 PolarHBondContact O-N 3.32Å; E227-S231 PolarHBondContact O-OG 3.36Å; F228-S231 PolarHBondContact O-N 3.22Å; S231-K235 WeakPolarHBondContact O-CB 3.35Å; S231-K235 PolarHBondContact O-N 3.47Å
232V98.8Very high98.7Very high0 Ų034.1 Ų34.10%019%0.189CC..Hα-helixtrans-63.3-51.4177.81640000111L137 I148 F228 E230 S234 K235 Y236 I242L137-V232 HydrophobicContact CD1-CG2 4.19Å; L137-V232 HydrophobicContact CD2-CG2 4.31Å; I148-V232 HydrophobicContact CD1-CB 4.32Å; I148-V232 HydrophobicContact CD1-CG1 3.28Å; I148-V232 HydrophobicContact CD1-CG2 4.02Å; F228-V232 HydrophobicContact CD2-CG2 3.95Å; F228-V232 HydrophobicContact CE1-CG2 4.3Å; F228-V232 HydrophobicContact CE2-CG2 3.54Å; F228-V232 HydrophobicContact CG-CG2 4.49Å; F228-V232 HydrophobicContact CZ-CG2 3.75Å; F228-V232 WeakPolarHBondContact O-CB 3.11Å; F228-V232 VanDerWaalsContact O-CG2 3.29Å; F228-V232 WeakPolarHBondContact O-CG2 3.27Å; F228-V232 PolarHBondContact O-N 2.63Å; E230-V232 PolarHBondContact O-N 3.06Å; V232-S234 VanDerWaalsContact C-N 3.33Å; V232-S234 PolarHBondContact O-N 2.78Å; V232-K235 PolarHBondContact O-N 2.59Å; V232-Y236 HydrophobicContact CG1-CD2 4.24Å; V232-Y236 PolarHBondContact O-N 2.83Å; V232-I242 HydrophobicContact CB-CD1 4.26Å; V232-I242 HydrophobicContact CG1-CD1 3.59Å; V232-I242 HydrophobicContact CG1-CG1 3.95Å
233S98.4Very high98.8Very high13 Ų1332.1 Ų32.19%0.09118%0.179CC..Hα-helixtrans-69.1-31.8-177.862.20000112.6M229 E230 G237 Y263M229-S233 VanDerWaalsContact O-CB 3.29Å; M229-S233 WeakPolarHBondContact O-CB 3.34Å; M229-S233 PolarHBondContact O-N 2.91Å; M229-S233 VanDerWaalsContact O-N 3.09Å; M229-S233 PolarHBondContact O-OG 2.64Å; E230-S233 PolarHBondContact O-N 3.49Å; E230-S233 PolarHBondContact O-OG 3.21Å; E230-S233 VanDerWaalsContact O-OG 3.07Å; S233-G237 CarbonylContact O-C 3.54Å; S233-G237 WeakPolarHBondContact O-CA 3.33Å; S233-G237 PolarHBondContact O-N 3.36Å; S233-Y263 WeakPolarHBondContact OG-CE1 3.08Å
234S98.7Very high98.8Very high103 Ų10329 Ų2972%0.7216%0.162SC*.Hα-helixtrans-67.5-41.3172.8-176.20000112.1E230 V232E230-S234 WeakPolarHBondContact O-CB 3.39Å; E230-S234 PolarHBondContact O-N 3.2Å; V232-S234 VanDerWaalsContact C-N 3.33Å; V232-S234 PolarHBondContact O-N 2.78Å
235K98.6Very high98.7Very high63 Ų6329.1 Ų29.127%0.27416%0.163SC..Hα-helixtrans-77.6-45.3-178.2-175.2179.6168.273.40112.4L137 N138 S231 V232L137-K235 HydrophobicContact CB-CD 3.48Å; L137-K235 VanDerWaalsContact CB-CD 3.48Å; L137-K235 HydrophobicContact CD1-CB 4.34Å; L137-K235 HydrophobicContact CD1-CD 4.12Å; L137-K235 HydrophobicContact CG-CD 4.4Å; L137-K235 VanDerWaalsContact O-CE 3.29Å; L137-K235 WeakPolarHBondContact O-CE 3.31Å; N138-K235 PolarHBondContact OD1-NZ 2.82Å; S231-K235 WeakPolarHBondContact O-CB 3.35Å; S231-K235 PolarHBondContact O-N 3.47Å; V232-K235 PolarHBondContact O-N 2.59Å
236Y98.8Very high98.6Very high28 Ų2829.3 Ų29.311%0.1116%0.164CC..Hα-helixtrans-106.2-3.2-170.9-55.4-56.8000114L137 D143 I145 I148 L189 V232L137-Y236 HydrophobicContact CD2-CE2 4.14Å; D143-Y236 WeakPolarHBondContact O-CD1 3.15Å; I145-Y236 HydrophobicContact CB-CD1 3.72Å; I145-Y236 HydrophobicContact CB-CD2 3.99Å; I145-Y236 HydrophobicContact CB-CE1 3.88Å; I145-Y236 HydrophobicContact CB-CE2 4.14Å; I145-Y236 HydrophobicContact CB-CG 3.77Å; I145-Y236 HydrophobicContact CG1-CD1 3.92Å; I145-Y236 HydrophobicContact CG1-CD2 4.43Å; I145-Y236 HydrophobicContact CG1-CE1 3.53Å; I145-Y236 HydrophobicContact CG1-CE2 4.1Å; I145-Y236 HydrophobicContact CG1-CG 4.35Å; I145-Y236 HydrophobicContact CG2-CD2 4.42Å; I148-Y236 HydrophobicContact CD1-CD2 4.32Å; L189-Y236 HydrophobicContact CD2-CE2 3.97Å; V232-Y236 HydrophobicContact CG1-CD2 4.24Å; V232-Y236 PolarHBondContact O-N 2.83Å
237G98.5Very high98.6Very high31 Ų3127.4 Ų27.432%0.3215%0.153SC..  trans90156.2179.300000113.8S233 N239 C240S233-G237 CarbonylContact O-C 3.54Å; S233-G237 WeakPolarHBondContact O-CA 3.33Å; S233-G237 PolarHBondContact O-N 3.36Å; G237-N239 PolarHBondContact O-N 2.74Å; G237-N239 VanDerWaalsContact O-N 3.09Å; G237-C240 VanDerWaalsContact O-CB 3.26Å; G237-C240 WeakPolarHBondContact O-CB 3.32Å; G237-C240 PolarHBondContact O-N 3.16Å
238M98.4Very high98.4Very high89 Ų8926.8 Ų26.844%0.43815%0.153SC..THydrogen-bonded Turntrans-62.4-17.7-178.3-65.2-57.8-60.200114.7C240 Q262 Y263M238-C240 VanDerWaalsContact C-N 3.32Å; M238-Q262 WeakPolarHBondContact CE-O 3.22Å; M238-Y263 HydrophobicContact CE-CD1 3.7Å; M238-Y263 HydrophobicContact CE-CE1 3.89Å; M238-Y263 HydrophobicContact SD-CD1 4.46Å; M238-Y263 HydrophobicContact SD-CE1 4.35Å
239N98.3Very high97.9Very high68 Ų6829.6 Ų29.636%0.36417%0.168SC..THydrogen-bonded Turntrans-85.7-2.6176-74.6-11.7000112.9G237 L241 T528G237-N239 PolarHBondContact O-N 2.74Å; G237-N239 VanDerWaalsContact O-N 3.09Å; N239-L241 PolarHBondContact O-N 3.49Å; N239-T528 PolarHBondContact ND2-OG1 3.32Å
240C98.8Very high97.5Very high6 Ų635 Ų354%0.04120%0.201CC..  trans-65.8120.3172.6-175.10000109.1G237 M238G237-C240 VanDerWaalsContact O-CB 3.26Å; G237-C240 WeakPolarHBondContact O-CB 3.32Å; G237-C240 PolarHBondContact O-N 3.16Å; M238-C240 VanDerWaalsContact C-N 3.32Å
241L98.9Very high97.3Very high0 Ų030.4 Ų30.40%018%0.18CC..EExtended strand (participates in β ladder)trans-69129.8174.6173.161.8000109.8K146 A147 I148 Y177 N239 C264 F266 A462 V465 V466 I473K146-L241 WeakPolarHBondContact O-CB 3.41Å; K146-L241 PolarHBondContact O-N 2.6Å; A147-L241 CarbonylContact C-O 3.57Å; A147-L241 WeakPolarHBondContact CA-O 3.45Å; A147-L241 HydrophobicContact CB-CB 4.42Å; A147-L241 HydrophobicContact CB-CD2 4.38Å; I148-L241 PolarHBondContact N-O 3.41Å; Y177-L241 HydrophobicContact CE1-CD2 4.12Å; N239-L241 PolarHBondContact O-N 3.49Å; L241-C264 WeakPolarHBondContact CA-O 3.35Å; L241-F266 HydrophobicContact CD1-CD1 3.8Å; L241-F266 HydrophobicContact CD1-CE1 3.86Å; L241-F266 HydrophobicContact CD2-CE1 4.25Å; L241-F266 HydrophobicContact CG-CE1 4.44Å; L241-A462 HydrophobicContact CD2-CB 3.54Å; L241-V465 HydrophobicContact CD1-CG1 4.37Å; L241-V466 HydrophobicContact CB-CG2 4.23Å; L241-V466 HydrophobicContact CD2-CG2 4.44Å; L241-I473 HydrophobicContact CD1-CD1 3.57Å
242I98.9Very high97.1Very high2 Ų229.7 Ų29.71%0.0118%0.175CC..EExtended strand (participates in β ladder)trans-121.1109.6173.5-55.9169000108.4V150 F228 M229 V232 F244 C264 T265 F266V150-I242 HydrophobicContact CG1-CG2 4.07Å; F228-I242 HydrophobicContact CE1-CG2 4.2Å; M229-I242 HydrophobicContact CE-CB 4.46Å; M229-I242 HydrophobicContact CE-CD1 3.64Å; M229-I242 HydrophobicContact CE-CG2 4.4Å; M229-I242 HydrophobicContact SD-CD1 3.81Å; M229-I242 HydrophobicContact SD-CG2 4.05Å; V232-I242 HydrophobicContact CB-CD1 4.26Å; V232-I242 HydrophobicContact CG1-CD1 3.59Å; V232-I242 HydrophobicContact CG1-CG1 3.95Å; I242-F244 HydrophobicContact CG2-CE2 4.35Å; I242-C264 PolarHBondContact N-O 2.54Å; I242-T265 WeakPolarHBondContact O-CA 3.08Å; I242-T265 WeakPolarHBondContact O-CB 3.27Å; I242-T265 PolarHBondContact O-OG1 2.78Å; I242-F266 PolarHBondContact O-N 2.86Å
243Q98.9Very high96.8Very high0 Ų030.9 Ų30.90%018%0.181CC..EExtended strand (participates in β ladder)trans-99.4124.5176.5-167.2-153.2-76.800110.3I148 V149 V150 K173 Y177 E245 F266 D268I148-Q243 PolarHBondContact O-N 3.13Å; V149-Q243 WeakPolarHBondContact CA-O 3.39Å; V149-Q243 HydrophobicContact CG2-CB 4.2Å; V150-Q243 PolarHBondContact N-O 3.5Å; K173-Q243 VanDerWaalsContact CD-NE2 3.32Å; K173-Q243 VanDerWaalsContact CE-NE2 3.26Å; Y177-Q243 PolarHBondContact OH-OE1 2.9Å; Q243-E245 PolarHBondContact NE2-OE2 3.02Å; Q243-F266 WeakPolarHBondContact CA-O 3.33Å; Q243-F266 HydrophobicContact CB-CD1 4.42Å; Q243-F266 HydrophobicContact CB-CE1 4Å; Q243-F266 HydrophobicContact CB-CZ 4.25Å; Q243-F266 HydrophobicContact CG-CD1 4.15Å; Q243-F266 HydrophobicContact CG-CD2 4.18Å; Q243-F266 HydrophobicContact CG-CE1 3.71Å; Q243-F266 HydrophobicContact CG-CE2 3.75Å; Q243-F266 HydrophobicContact CG-CG 4.4Å; Q243-F266 HydrophobicContact CG-CZ 3.51Å; Q243-D268 HydrophobicContact CG-CB 4.37Å
244F98.9Very high96.7Very high3 Ų333.9 Ų33.91%0.01319%0.19CC..EExtended strand (participates in β ladder)trans-83.2141.4169.1-68.7-93.1000110.7V150 L225 M229 I242 F247 L255 Y259 T265 F266 N267 D268V150-F244 HydrophobicContact CG1-CD1 4.08Å; V150-F244 HydrophobicContact CG1-CE1 4.24Å; V150-F244 HydrophobicContact CG1-CG 4.43Å; L225-F244 HydrophobicContact CD1-CE1 4.17Å; M229-F244 HydrophobicContact CE-CE2 4.35Å; M229-F244 HydrophobicContact CE-CZ 4.39Å; M229-F244 HydrophobicContact SD-CE2 4.21Å; M229-F244 HydrophobicContact SD-CZ 3.74Å; I242-F244 HydrophobicContact CG2-CE2 4.35Å; F244-F247 HydrophobicContact CB-CD2 4.1Å; F244-F247 HydrophobicContact CB-CE2 4.08Å; F244-F247 AromaticContact CD1-CD2 3.98Å; F244-F247 HydrophobicContact CD1-CD2 3.98Å; F244-F247 HydrophobicContact CD1-CE1 4.34Å; F244-F247 AromaticContact CD1-CE2 3.45Å; F244-F247 HydrophobicContact CD1-CE2 3.45Å; F244-F247 VanDerWaalsContact CD1-CE2 3.45Å; F244-F247 AromaticContact CD1-CZ 3.66Å; F244-F247 HydrophobicContact CD1-CZ 3.66Å; F244-F247 HydrophobicContact CE1-CE2 4.35Å; F244-F247 HydrophobicContact CE1-CZ 4.13Å; F244-F247 HydrophobicContact CG-CE2 4.24Å; F244-L255 HydrophobicContact CD1-CD1 4.4Å; F244-L255 HydrophobicContact CE1-CB 4.39Å; F244-L255 HydrophobicContact CE1-CD1 4.12Å; F244-Y259 HydrophobicContact CE2-CD2 4.08Å; F244-Y259 AromaticContact CZ-CD2 3.7Å; F244-Y259 HydrophobicContact CZ-CD2 3.7Å; F244-Y259 HydrophobicContact CZ-CE2 4.02Å; F244-T265 VanDerWaalsContact CD2-OG1 3.31Å; F244-T265 WeakPolarHBondContact CD2-OG1 3.39Å; F244-T265 WeakPolarHBondContact CE2-OG1 3.39Å; F244-F266 PolarHBondContact N-O 2.91Å; F244-N267 HydrophobicContact CB-CB 4.1Å; F244-N267 WeakPolarHBondContact O-CA 3.25Å; F244-D268 PolarHBondContact O-N 2.97Å
245E98.4Very high96.7Very high3 Ų329 Ų291%0.01416%0.155CC..  trans-145.6137.3-177-172.974.8177.900111Y102 V149 V150 T151 I169 K173 Q243 F247 D268Y102-E245 PolarHBondContact OH-OE1 3.34Å; V149-E245 HydrophobicContact CG1-CB 3.96Å; V149-E245 HydrophobicContact CG1-CG 4.5Å; V150-E245 PolarHBondContact O-N 3.1Å; T151-E245 WeakPolarHBondContact CA-O 3.35Å; T151-E245 WeakPolarHBondContact CB-O 3.42Å; T151-E245 PolarHBondContact OG1-O 3.14Å; I169-E245 HydrophobicContact CG2-CG 3.59Å; K173-E245 VanDerWaalsContact CD-CD 3.49Å; K173-E245 HydrophobicContact CD-CG 4.2Å; K173-E245 VanDerWaalsContact CD-OE2 3.22Å; K173-E245 WeakPolarHBondContact CD-OE2 3.33Å; K173-E245 WeakPolarHBondContact CE-OE2 3.37Å; K173-E245 IonicContact NZ-OE1 3.19Å; K173-E245 PolarHBondContact NZ-OE1 3.37Å; K173-E245 IonicContact NZ-OE2 3.05Å; K173-E245 PolarHBondContact NZ-OE2 3.18Å; Q243-E245 PolarHBondContact NE2-OE2 3.02Å; E245-F247 WeakPolarHBondContact O-CD2 3.44Å; E245-F247 PolarHBondContact O-N 3.25Å; E245-F247 VanDerWaalsContact O-N 3.12Å; E245-D268 WeakPolarHBondContact OE2-CB 3.39Å
246D96.6Very high96.7Very high4 Ų426.1 Ų26.12%0.02114%0.143CC..SBendtrans55.232.3169.1-76.9-18000114.9R155 I156 L157 I169 D269R155-D246 CarbonylContact C-O 3.08Å; R155-D246 WeakPolarHBondContact CA-O 3.42Å; R155-D246 PolarHBondContact N-O 3.42Å; R155-D246 WeakPolarHBondContact O-CB 3.05Å; I156-D246 WeakPolarHBondContact CA-OD2 3.31Å; I156-D246 HydrophobicContact CD1-CB 3.77Å; L157-D246 PolarHBondContact N-OD1 2.8Å; I169-D246 WeakPolarHBondContact CG2-OD2 3.33Å; D246-D269 PolarHBondContact N-OD2 2.78Å
247F98.1Very high96.6Very high0 Ų028.6 Ų28.60%016%0.158CC..  trans-79153.9167.8-75.7-100.7000110.1V150 D152 Y221 F244 E245 A252 L255 E304V150-F247 WeakPolarHBondContact O-CE2 3.36Å; D152-F247 HydrophobicContact CB-CD1 4.16Å; D152-F247 HydrophobicContact CB-CE1 3.74Å; D152-F247 HydrophobicContact CB-CZ 4.26Å; D152-F247 WeakPolarHBondContact OD2-CD1 3.31Å; Y221-F247 WeakPolarHBondContact OH-CD1 3.35Å; Y221-F247 WeakPolarHBondContact OH-CE1 3.31Å; F244-F247 HydrophobicContact CB-CD2 4.1Å; F244-F247 HydrophobicContact CB-CE2 4.08Å; F244-F247 AromaticContact CD1-CD2 3.98Å; F244-F247 HydrophobicContact CD1-CD2 3.98Å; F244-F247 HydrophobicContact CD1-CE1 4.34Å; F244-F247 AromaticContact CD1-CE2 3.45Å; F244-F247 HydrophobicContact CD1-CE2 3.45Å; F244-F247 VanDerWaalsContact CD1-CE2 3.45Å; F244-F247 AromaticContact CD1-CZ 3.66Å; F244-F247 HydrophobicContact CD1-CZ 3.66Å; F244-F247 HydrophobicContact CE1-CE2 4.35Å; F244-F247 HydrophobicContact CE1-CZ 4.13Å; F244-F247 HydrophobicContact CG-CE2 4.24Å; E245-F247 WeakPolarHBondContact O-CD2 3.44Å; E245-F247 PolarHBondContact O-N 3.25Å; E245-F247 VanDerWaalsContact O-N 3.12Å; F247-A252 HydrophobicContact CB-CB 4.09Å; F247-L255 HydrophobicContact CD1-CD1 3.95Å; F247-L255 HydrophobicContact CE1-CD1 4.02Å; F247-E304 VanDerWaalsContact O-OE1 3.11Å
248A94.5Very high96.6Very high18 Ų1830.2 Ų30.215%0.14916%0.157CC..  trans-64.5146.8171.600000112.4E154 V250 N251 A252E154-A248 HydrophobicContact CB-CB 4.31Å; E154-A248 HydrophobicContact CG-CB 3.85Å; E154-A248 WeakPolarHBondContact OE1-CB 3.43Å; E154-A248 WeakPolarHBondContact OE2-CB 3.38Å; A248-V250 VanDerWaalsContact C-N 3.29Å; A248-V250 PolarHBondContact O-N 2.97Å; A248-N251 WeakPolarHBondContact O-CA 3.07Å; A248-N251 PolarHBondContact O-N 3.45Å; A248-A252 PolarHBondContact O-N 3.36Å
249N87.9Confident96.6Very high58 Ų5826.1 Ų26.131%0.3114%0.136SC..Hα-helixtrans-46.3-44.8-170.2-58.745.5000115.3R155 F253 G303 E304R155-N249 WeakPolarHBondContact CD-OD1 3.28Å; R155-N249 PolarHBondContact NE-OD1 2.97Å; R155-N249 VanDerWaalsContact NE-OD1 3.1Å; N249-F253 WeakPolarHBondContact O-CD2 3.28Å; N249-F253 PolarHBondContact O-N 2.71Å; N249-G303 WeakPolarHBondContact ND2-CA 3.43Å; N249-E304 WeakPolarHBondContact CA-OE1 3.37Å; N249-E304 HydrophobicContact CB-CG 4.13Å; N249-E304 VanDerWaalsContact CG-OE1 3.3Å; N249-E304 PolarHBondContact N-OE1 3.49Å; N249-E304 VanDerWaalsContact N-OE1 3.09Å; N249-E304 PolarHBondContact OD1-OE1 2.85Å; N249-E304 VanDerWaalsContact OD1-OE1 3.08Å
250V90.3Very high96.6Very high114 Ų11424.8 Ų24.869%0.69113%0.126SC*.Hα-helixtrans-65.1-44.7-178.4177.30000110.6A248 R254A248-V250 VanDerWaalsContact C-N 3.29Å; A248-V250 PolarHBondContact O-N 2.97Å; V250-R254 WeakPolarHBondContact O-CB 3.33Å; V250-R254 PolarHBondContact O-N 2.97Å
251N95.3Very high96.6Very high18 Ų1830.2 Ų30.210%0.09616%0.155CC..Hα-helixtrans-71.7-42.3178.5-75.3-24.4000111.5A248 F253 R254 L255A248-N251 WeakPolarHBondContact O-CA 3.07Å; A248-N251 PolarHBondContact O-N 3.45Å; N251-F253 PolarHBondContact O-N 3.48Å; N251-R254 PolarHBondContact O-N 2.9Å; N251-R254 PolarHBondContact OD1-NH2 3.42Å; N251-L255 HydrophobicContact CB-CD1 4.21Å; N251-L255 VanDerWaalsContact O-CB 3.27Å; N251-L255 WeakPolarHBondContact O-CB 3.5Å; N251-L255 WeakPolarHBondContact O-CG 3.26Å; N251-L255 PolarHBondContact O-N 3.02Å
252A95.1Very high96.5Very high2 Ų235.3 Ų35.32%0.01718%0.178CC..Hα-helixtrans-53.4-52.3179.500000112.1F247 A248 L256 I270 E304F247-A252 HydrophobicContact CB-CB 4.09Å; A248-A252 PolarHBondContact O-N 3.36Å; A252-L256 VanDerWaalsContact O-CB 3.23Å; A252-L256 WeakPolarHBondContact O-CB 3.28Å; A252-L256 PolarHBondContact O-N 3.46Å; A252-L256 VanDerWaalsContact O-N 3.08Å; A252-I270 HydrophobicContact CB-CD1 3.96Å; A252-E304 HydrophobicContact CB-CG 3.95Å
253F93.4Very high96.5Very high26 Ų2636.5 Ų36.511%0.11418%0.183CC..Hα-helixtrans-67.6-43.8177.8-81.1-68.4000113.1N249 N251 L256 N257 I270 E304 L307N249-F253 WeakPolarHBondContact O-CD2 3.28Å; N249-F253 PolarHBondContact O-N 2.71Å; N251-F253 PolarHBondContact O-N 3.48Å; F253-L256 PolarHBondContact O-N 3.26Å; F253-N257 WeakPolarHBondContact O-CB 3.01Å; F253-N257 VanDerWaalsContact O-CG 3.28Å; F253-N257 PolarHBondContact O-N 3.32Å; F253-N257 PolarHBondContact O-ND2 3.35Å; F253-N257 VanDerWaalsContact O-ND2 3.15Å; F253-I270 HydrophobicContact CD1-CD1 3.69Å; F253-I270 HydrophobicContact CD1-CG1 4.44Å; F253-I270 HydrophobicContact CD1-CG2 4.49Å; F253-I270 HydrophobicContact CD2-CD1 4.31Å; F253-I270 HydrophobicContact CE1-CD1 3.72Å; F253-I270 HydrophobicContact CE1-CG1 3.97Å; F253-I270 HydrophobicContact CE1-CG2 3.69Å; F253-I270 HydrophobicContact CE2-CD1 4.34Å; F253-I270 HydrophobicContact CE2-CG1 4.46Å; F253-I270 HydrophobicContact CG-CD1 3.97Å; F253-I270 HydrophobicContact CZ-CD1 4.03Å; F253-I270 HydrophobicContact CZ-CG1 3.95Å; F253-I270 HydrophobicContact CZ-CG2 4.16Å; F253-E304 HydrophobicContact CD2-CG 4.35Å; F253-E304 HydrophobicContact CE2-CB 4.29Å; F253-E304 HydrophobicContact CE2-CG 3.92Å; F253-L307 HydrophobicContact CE1-CB 4.4Å; F253-L307 HydrophobicContact CE2-CB 4.3Å; F253-L307 HydrophobicContact CE2-CD1 3.82Å; F253-L307 HydrophobicContact CZ-CB 3.65Å; F253-L307 HydrophobicContact CZ-CD1 4Å; F253-L307 HydrophobicContact CZ-CG 4.49Å
254R96.4Very high96.5Very high75 Ų7536.5 Ų36.528%0.28318%0.183SC..Hα-helixtrans-62.9-48.3-177.5-177.5179.862.482.5-1.2111.5D222 V250 N251 N257 K258D222-R254 IonicContact OD1-CZ 2.67Å; D222-R254 IonicContact OD1-NH1 3.65Å; D222-R254 PolarHBondContact OD1-NH1 3.49Å; D222-R254 IonicContact OD1-NH2 3.85Å; D222-R254 PolarHBondContact OD1-NH2 2.95Å; D222-R254 IonicContact OD2-CZ 2.62Å; D222-R254 IonicContact OD2-NH1 3.93Å; D222-R254 PolarHBondContact OD2-NH1 3.24Å; D222-R254 VanDerWaalsContact OD2-NH1 3.17Å; V250-R254 WeakPolarHBondContact O-CB 3.33Å; V250-R254 PolarHBondContact O-N 2.97Å; N251-R254 PolarHBondContact O-N 2.9Å; N251-R254 PolarHBondContact OD1-NH2 3.42Å; R254-N257 PolarHBondContact O-N 3.39Å; R254-K258 WeakPolarHBondContact O-CB 3.22Å; R254-K258 PolarHBondContact O-N 2.72Å
255L98.3Very high96.5Very high0 Ų036.4 Ų36.40%018%0.183CC..Hα-helixtrans-66.3-42.9179.1-63172.6000111Y221 L225 F244 F247 N251 N257 K258 Y259Y221-L255 HydrophobicContact CE1-CD1 4.43Å; L225-L255 HydrophobicContact CB-CD2 4.3Å; L225-L255 HydrophobicContact CD1-CD1 4.41Å; L225-L255 HydrophobicContact CG-CD1 4.39Å; L225-L255 HydrophobicContact CG-CD2 4.21Å; F244-L255 HydrophobicContact CD1-CD1 4.4Å; F244-L255 HydrophobicContact CE1-CB 4.39Å; F244-L255 HydrophobicContact CE1-CD1 4.12Å; F247-L255 HydrophobicContact CD1-CD1 3.95Å; F247-L255 HydrophobicContact CE1-CD1 4.02Å; N251-L255 HydrophobicContact CB-CD1 4.21Å; N251-L255 VanDerWaalsContact O-CB 3.27Å; N251-L255 WeakPolarHBondContact O-CB 3.5Å; N251-L255 WeakPolarHBondContact O-CG 3.26Å; N251-L255 PolarHBondContact O-N 3.02Å; L255-N257 PolarHBondContact O-N 3.28Å; L255-K258 PolarHBondContact O-N 2.94Å; L255-Y259 HydrophobicContact CB-CD2 4.28Å; L255-Y259 HydrophobicContact CB-CE2 4.21Å; L255-Y259 HydrophobicContact CD2-CE2 3.75Å; L255-Y259 VanDerWaalsContact O-CD2 3.3Å; L255-Y259 WeakPolarHBondContact O-CD2 3.23Å; L255-Y259 PolarHBondContact O-N 3.01Å
256L98Very high96.5Very high4 Ų436.2 Ų36.22%0.02118%0.182CC..Hα-helixtrans-56.9-50.5174.417661.2000111.1A252 F253 K258 Y259 R260 N267 I270 Q271A252-L256 VanDerWaalsContact O-CB 3.23Å; A252-L256 WeakPolarHBondContact O-CB 3.28Å; A252-L256 PolarHBondContact O-N 3.46Å; A252-L256 VanDerWaalsContact O-N 3.08Å; F253-L256 PolarHBondContact O-N 3.26Å; L256-K258 VanDerWaalsContact C-N 3.33Å; L256-K258 PolarHBondContact O-N 2.98Å; L256-Y259 PolarHBondContact O-N 3.31Å; L256-R260 HydrophobicContact CD1-CB 4.14Å; L256-R260 WeakPolarHBondContact O-CB 3.41Å; L256-R260 WeakPolarHBondContact O-CD 3.43Å; L256-R260 WeakPolarHBondContact O-CG 3.32Å; L256-R260 PolarHBondContact O-N 3.02Å; L256-N267 HydrophobicContact CD1-CB 4.48Å; L256-N267 HydrophobicContact CD2-CB 4.39Å; L256-I270 HydrophobicContact CD2-CB 4.39Å; L256-I270 HydrophobicContact CD2-CD1 4Å; L256-I270 HydrophobicContact CD2-CG2 4.13Å; L256-Q271 HydrophobicContact CD2-CG 4.08Å
257N96.9Very high96.6Very high79 Ų7936.1 Ų36.142%0.42218%0.181SC..Hα-helixtrans-65.2-35.9-179.4-72.3-32.3000112.7F253 R254 L255F253-N257 WeakPolarHBondContact O-CB 3.01Å; F253-N257 VanDerWaalsContact O-CG 3.28Å; F253-N257 PolarHBondContact O-N 3.32Å; F253-N257 PolarHBondContact O-ND2 3.35Å; F253-N257 VanDerWaalsContact O-ND2 3.15Å; R254-N257 PolarHBondContact O-N 3.39Å; L255-N257 PolarHBondContact O-N 3.28Å
258K98.4Very high96.6Very high66 Ų6636.1 Ų36.129%0.28718%0.181SC..Hα-helixtrans-64.7-47176.9-171.3179.3-178.7-169.50111.6D226 R254 L255 L256 Q262D226-K258 WeakPolarHBondContact OD1-CE 3.39Å; D226-K258 IonicContact OD1-NZ 3.9Å; D226-K258 PolarHBondContact OD1-NZ 3.21Å; D226-K258 IonicContact OD2-NZ 2.86Å; D226-K258 PolarHBondContact OD2-NZ 3.22Å; R254-K258 WeakPolarHBondContact O-CB 3.22Å; R254-K258 PolarHBondContact O-N 2.72Å; L255-K258 PolarHBondContact O-N 2.94Å; L256-K258 VanDerWaalsContact C-N 3.33Å; L256-K258 PolarHBondContact O-N 2.98Å; K258-Q262 PolarHBondContact O-NE2 2.82Å
259Y98.8Very high96.6Very high2 Ų235.7 Ų35.71%0.00818%0.177CC..Hα-helixtrans-99.7-22-166.7-60-42.1000115.8D226 M229 F244 L255 L256 N261 Q262 Y263D226-Y259 PolarHBondContact N-OH 2.7Å; D226-Y259 VanDerWaalsContact OD1-CE1 3.3Å; D226-Y259 WeakPolarHBondContact OD1-CE1 3.21Å; D226-Y259 PolarHBondContact OD1-OH 3.47Å; M229-Y259 HydrophobicContact CE-CD2 4.08Å; M229-Y259 HydrophobicContact CE-CG 3.99Å; M229-Y259 HydrophobicContact CG-CD1 4.28Å; M229-Y259 HydrophobicContact CG-CD2 3.99Å; M229-Y259 HydrophobicContact CG-CE1 4.1Å; M229-Y259 HydrophobicContact CG-CE2 3.76Å; M229-Y259 HydrophobicContact CG-CG 4.26Å; M229-Y259 HydrophobicContact SD-CD2 4.21Å; M229-Y259 HydrophobicContact SD-CE2 4.39Å; F244-Y259 HydrophobicContact CE2-CD2 4.08Å; F244-Y259 AromaticContact CZ-CD2 3.7Å; F244-Y259 HydrophobicContact CZ-CD2 3.7Å; F244-Y259 HydrophobicContact CZ-CE2 4.02Å; L255-Y259 HydrophobicContact CB-CD2 4.28Å; L255-Y259 HydrophobicContact CB-CE2 4.21Å; L255-Y259 HydrophobicContact CD2-CE2 3.75Å; L255-Y259 VanDerWaalsContact O-CD2 3.3Å; L255-Y259 WeakPolarHBondContact O-CD2 3.23Å; L255-Y259 PolarHBondContact O-N 3.01Å; L256-Y259 PolarHBondContact O-N 3.31Å; Y259-N261 PolarHBondContact O-N 2.89Å; Y259-Q262 PolarHBondContact O-N 3.2Å; Y259-Y263 HydrophobicContact CD1-CD2 4.02Å; Y259-Y263 HydrophobicContact CD1-CE2 4.01Å; Y259-Y263 HydrophobicContact CG-CD2 4.28Å; Y259-Y263 PolarHBondContact O-N 2.78Å
260R98Very high97.1Very high41 Ų4133.3 Ų33.316%0.15516%0.164CC..THydrogen-bonded Turntrans-55.9-25.8-17263.7-170.1-62.1172.74116.2L256 D475L256-R260 HydrophobicContact CD1-CB 4.14Å; L256-R260 WeakPolarHBondContact O-CB 3.41Å; L256-R260 WeakPolarHBondContact O-CD 3.43Å; L256-R260 WeakPolarHBondContact O-CG 3.32Å; L256-R260 PolarHBondContact O-N 3.02Å; R260-D475 IonicContact CZ-OD1 2.55Å; R260-D475 IonicContact CZ-OD2 3.93Å; R260-D475 IonicContact NH1-OD2 2.98Å; R260-D475 IonicContact NH2-OD1 3.87Å; R260-D475 PolarHBondContact NH2-OD1 2.89Å; R260-D475 IonicContact NH2-OD2 2.85Å; R260-D475 PolarHBondContact NH2-OD2 2.88Å
261N97.9Very high97.4Very high119 Ų11928.2 Ų28.264%0.63613%0.132SC*.THydrogen-bonded Turntrans-103.34.4-179.5-61.1-47.1000113.3Y259 H472Y259-N261 PolarHBondContact O-N 2.89Å; N261-H472 PolarHBondContact O-CE1 3.22Å
262Q98.1Very high97.6Very high107 Ų10727.3 Ų27.350%0.513%0.128SC..THydrogen-bonded Turntrans-118.2-38.7-177.6-57.1-175.152.900110.9M238 K258 Y259M238-Q262 WeakPolarHBondContact CE-O 3.22Å; K258-Q262 PolarHBondContact O-NE2 2.82Å; Y259-Q262 PolarHBondContact O-N 3.2Å
263Y98.8Very high97.6Very high27 Ų2728 Ų2811%0.10613%0.132CC..SBendtrans-118.9162.7-178.2-61.7-76.6000111.6M229 S233 M238 Y259 T265 R471 H472M229-Y263 HydrophobicContact CB-CD2 4.21Å; M229-Y263 HydrophobicContact CB-CE1 4.3Å; M229-Y263 HydrophobicContact CB-CE2 3.7Å; M229-Y263 HydrophobicContact CE-CD1 4.28Å; M229-Y263 HydrophobicContact CE-CD2 3.49Å; M229-Y263 VanDerWaalsContact CE-CD2 3.49Å; M229-Y263 HydrophobicContact CE-CE2 4.19Å; M229-Y263 HydrophobicContact CE-CG 3.53Å; M229-Y263 HydrophobicContact CG-CE2 4.43Å; S233-Y263 WeakPolarHBondContact OG-CE1 3.08Å; M238-Y263 HydrophobicContact CE-CD1 3.7Å; M238-Y263 HydrophobicContact CE-CE1 3.89Å; M238-Y263 HydrophobicContact SD-CD1 4.46Å; M238-Y263 HydrophobicContact SD-CE1 4.35Å; Y259-Y263 HydrophobicContact CD1-CD2 4.02Å; Y259-Y263 HydrophobicContact CD1-CE2 4.01Å; Y259-Y263 HydrophobicContact CG-CD2 4.28Å; Y259-Y263 PolarHBondContact O-N 2.78Å; Y263-T265 VanDerWaalsContact C-N 3.28Å; Y263-T265 PolarHBondContact O-N 2.8Å; Y263-R471 CarbonylContact C-O 3.55Å; Y263-H472 PolarHBondContact O-ND1 3.14Å
264C98.8Very high97.9Very high1 Ų126.9 Ų26.91%0.00713%0.127CC..SBendtrans-77.780168.5-179.60000109.4L241 I242 V465 L470 R471L241-C264 WeakPolarHBondContact CA-O 3.35Å; I242-C264 PolarHBondContact N-O 2.54Å; C264-V465 WeakPolarHBondContact SG-CG1 3.13Å; C264-L470 PolarHBondContact SG-O 3.26Å; C264-L470 VanDerWaalsContact SG-O 3.33Å; C264-R471 VanDerWaalsContact CA-O 3.22Å; C264-R471 WeakPolarHBondContact CA-O 3.41Å; C264-R471 WeakPolarHBondContact CB-O 3.34Å; C264-R471 PolarHBondContact N-O 2.71Å
265T98.9Very high98Very high0 Ų023.3 Ų23.30%011%0.114CC..EExtended strand (participates in β ladder)trans-138.3152.8-172.7-173.70000113.6M229 I242 F244 Y263M229-T265 HydrophobicContact CE-CG2 4.47Å; I242-T265 WeakPolarHBondContact O-CA 3.08Å; I242-T265 WeakPolarHBondContact O-CB 3.27Å; I242-T265 PolarHBondContact O-OG1 2.78Å; F244-T265 VanDerWaalsContact CD2-OG1 3.31Å; F244-T265 WeakPolarHBondContact CD2-OG1 3.39Å; F244-T265 WeakPolarHBondContact CE2-OG1 3.39Å; Y263-T265 VanDerWaalsContact C-N 3.28Å; Y263-T265 PolarHBondContact O-N 2.8Å
266F98.8Very high98Very high0 Ų023.4 Ų23.40%011%0.114CC..EExtended strand (participates in β ladder)trans-151.2167.4170.477.6-81.3000110L241 I242 Q243 F244 D268 Q271 F458 I473 F478L241-F266 HydrophobicContact CD1-CD1 3.8Å; L241-F266 HydrophobicContact CD1-CE1 3.86Å; L241-F266 HydrophobicContact CD2-CE1 4.25Å; L241-F266 HydrophobicContact CG-CE1 4.44Å; I242-F266 PolarHBondContact O-N 2.86Å; Q243-F266 WeakPolarHBondContact CA-O 3.33Å; Q243-F266 HydrophobicContact CB-CD1 4.42Å; Q243-F266 HydrophobicContact CB-CE1 4Å; Q243-F266 HydrophobicContact CB-CZ 4.25Å; Q243-F266 HydrophobicContact CG-CD1 4.15Å; Q243-F266 HydrophobicContact CG-CD2 4.18Å; Q243-F266 HydrophobicContact CG-CE1 3.71Å; Q243-F266 HydrophobicContact CG-CE2 3.75Å; Q243-F266 HydrophobicContact CG-CG 4.4Å; Q243-F266 HydrophobicContact CG-CZ 3.51Å; F244-F266 PolarHBondContact N-O 2.91Å; F266-D268 HydrophobicContact CE2-CB 4.04Å; F266-Q271 VanDerWaalsContact CB-OE1 3.27Å; F266-F458 HydrophobicContact CE2-CB 4.45Å; F266-F458 HydrophobicContact CZ-CB 4.12Å; F266-I473 HydrophobicContact CB-CD1 4.11Å; F266-I473 HydrophobicContact CD1-CD1 3.53Å; F266-I473 HydrophobicContact CE1-CD1 4.33Å; F266-I473 HydrophobicContact CG-CD1 4.2Å; F266-F478 HydrophobicContact CB-CE2 4.22Å; F266-F478 HydrophobicContact CB-CZ 3.77Å; F266-F478 AromaticContact CD2-CE1 3.98Å; F266-F478 HydrophobicContact CD2-CE1 3.98Å; F266-F478 AromaticContact CD2-CZ 3.54Å; F266-F478 HydrophobicContact CD2-CZ 3.54Å; F266-F478 HydrophobicContact CE2-CE1 4.26Å; F266-F478 HydrophobicContact CE2-CZ 4.22Å; F266-F478 AromaticContact CG-CZ 3.77Å; F266-F478 HydrophobicContact CG-CZ 3.77Å
267N98.7Very high98Very high1 Ų123.2 Ų23.21%0.00511%0.113CC..EExtended strand (participates in β ladder)trans-116.9125.6171.8175.1-67.9000108.8F244 L256 D269 I270 Q271F244-N267 HydrophobicContact CB-CB 4.1Å; F244-N267 WeakPolarHBondContact O-CA 3.25Å; L256-N267 HydrophobicContact CD1-CB 4.48Å; L256-N267 HydrophobicContact CD2-CB 4.39Å; N267-D269 WeakPolarHBondContact OD1-CA 3.29Å; N267-D269 WeakPolarHBondContact OD1-CB 3.39Å; N267-D269 PolarHBondContact OD1-N 3.18Å; N267-I270 HydrophobicContact CB-CB 4.46Å; N267-I270 HydrophobicContact CB-CD1 4.24Å; N267-I270 WeakPolarHBondContact OD1-CG1 3.43Å; N267-I270 PolarHBondContact OD1-N 3.22Å; N267-Q271 WeakPolarHBondContact O-CB 3.46Å; N267-Q271 PolarHBondContact O-N 2.95Å
268D97.9Very high98.1Very high0 Ų019.5 Ų19.50%09%0.094CC..Iπ-helixtrans-75-35.9-174.9-170.168.9000112.7K173 Q243 F244 E245 F266 I270 G272 T273 N454 F458K173-D268 WeakPolarHBondContact CE-OD2 3.24Å; K173-D268 IonicContact NZ-OD2 3.81Å; K173-D268 PolarHBondContact NZ-OD2 2.98Å; Q243-D268 HydrophobicContact CG-CB 4.37Å; F244-D268 PolarHBondContact O-N 2.97Å; E245-D268 WeakPolarHBondContact OE2-CB 3.39Å; F266-D268 HydrophobicContact CE2-CB 4.04Å; D268-I270 PolarHBondContact O-N 2.72Å; D268-G272 CarbonylContact O-C 3.59Å; D268-G272 WeakPolarHBondContact O-CA 3.4Å; D268-G272 PolarHBondContact O-N 3.01Å; D268-G272 WeakPolarHBondContact OD1-CA 3.35Å; D268-T273 PolarHBondContact O-N 3.04Å; D268-T273 PolarHBondContact O-OG1 3.05Å; D268-N454 PolarHBondContact O-ND2 2.91Å; D268-N454 WeakPolarHBondContact OD2-CB 3.25Å; D268-N454 PolarHBondContact OD2-ND2 2.88Å; D268-F458 WeakPolarHBondContact OD1-CB 3.29Å
269D95Very high98.2Very high10 Ų1016.4 Ų16.45%0.0538%0.08CC..Iπ-helixtrans-59.8-34.1176.8-62.8-67.6000112.9D246 N267 T273 E304D246-D269 PolarHBondContact N-OD2 2.78Å; N267-D269 WeakPolarHBondContact OD1-CA 3.29Å; N267-D269 WeakPolarHBondContact OD1-CB 3.39Å; N267-D269 PolarHBondContact OD1-N 3.18Å; D269-T273 WeakPolarHBondContact O-CB 3.31Å; D269-T273 PolarHBondContact O-OG1 2.78Å; D269-E304 WeakPolarHBondContact CB-OE2 3.1Å
270I96.8Very high98.2Very high7 Ų716.3 Ų16.34%0.0368%0.08CC..Iπ-helixtrans-88.6-62.3176.5-61.8164.6000110.7A252 F253 L256 N267 D268 A274 E304A252-I270 HydrophobicContact CB-CD1 3.96Å; F253-I270 HydrophobicContact CD1-CD1 3.69Å; F253-I270 HydrophobicContact CD1-CG1 4.44Å; F253-I270 HydrophobicContact CD1-CG2 4.49Å; F253-I270 HydrophobicContact CD2-CD1 4.31Å; F253-I270 HydrophobicContact CE1-CD1 3.72Å; F253-I270 HydrophobicContact CE1-CG1 3.97Å; F253-I270 HydrophobicContact CE1-CG2 3.69Å; F253-I270 HydrophobicContact CE2-CD1 4.34Å; F253-I270 HydrophobicContact CE2-CG1 4.46Å; F253-I270 HydrophobicContact CG-CD1 3.97Å; F253-I270 HydrophobicContact CZ-CD1 4.03Å; F253-I270 HydrophobicContact CZ-CG1 3.95Å; F253-I270 HydrophobicContact CZ-CG2 4.16Å; L256-I270 HydrophobicContact CD2-CB 4.39Å; L256-I270 HydrophobicContact CD2-CD1 4Å; L256-I270 HydrophobicContact CD2-CG2 4.13Å; N267-I270 HydrophobicContact CB-CB 4.46Å; N267-I270 HydrophobicContact CB-CD1 4.24Å; N267-I270 WeakPolarHBondContact OD1-CG1 3.43Å; N267-I270 PolarHBondContact OD1-N 3.22Å; D268-I270 PolarHBondContact O-N 2.72Å; I270-A274 VanDerWaalsContact O-CB 3.24Å; I270-A274 WeakPolarHBondContact O-CB 3.31Å; I270-A274 PolarHBondContact O-N 2.7Å; I270-E304 HydrophobicContact CD1-CG 4.33Å; I270-E304 HydrophobicContact CG1-CB 3.73Å; I270-E304 HydrophobicContact CG1-CG 3.94Å
271Q98.5Very high98.2Very high7 Ų714.5 Ų14.53%0.0337%0.073CC..Iπ-helixtrans-89.9-34.8-166.4-61.7175-81.300112.9L256 F266 N267 A274 S275 D475 F478L256-Q271 HydrophobicContact CD2-CG 4.08Å; F266-Q271 VanDerWaalsContact CB-OE1 3.27Å; N267-Q271 WeakPolarHBondContact O-CB 3.46Å; N267-Q271 PolarHBondContact O-N 2.95Å; Q271-A274 PolarHBondContact O-N 2.64Å; Q271-S275 PolarHBondContact O-N 2.78Å; Q271-D475 PolarHBondContact NE2-OD1 2.65Å; Q271-F478 HydrophobicContact CB-CD1 4.1Å; Q271-F478 HydrophobicContact CB-CD2 3.81Å; Q271-F478 HydrophobicContact CB-CE1 3.91Å; Q271-F478 HydrophobicContact CB-CE2 3.6Å; Q271-F478 HydrophobicContact CB-CG 4.05Å; Q271-F478 HydrophobicContact CB-CZ 3.67Å; Q271-F478 HydrophobicContact CG-CD2 4.37Å; Q271-F478 HydrophobicContact CG-CE2 4.13Å; Q271-F478 VanDerWaalsContact NE2-CE2 3.33Å; Q271-F478 WeakPolarHBondContact O-CD1 3.34Å
272G97.8Very high98.2Very high0 Ų010.6 Ų10.60%05%0.052CC..Iπ-helixtrans-65.6-50.7174.400000111.6D268 A274 S275 V276D268-G272 CarbonylContact O-C 3.59Å; D268-G272 WeakPolarHBondContact O-CA 3.4Å; D268-G272 PolarHBondContact O-N 3.01Å; D268-G272 WeakPolarHBondContact OD1-CA 3.35Å; G272-A274 VanDerWaalsContact C-N 3.28Å; G272-A274 PolarHBondContact O-N 3.28Å; G272-S275 PolarHBondContact O-N 2.93Å; G272-S275 VanDerWaalsContact O-N 3.13Å; G272-V276 PolarHBondContact O-N 2.66Å
273T96.6Very high98.3Very high17 Ų175.5 Ų5.510%0.1043%0.028CC..Hα-helixtrans-57.8-41174.7-50.50000111.7D268 D269 V276 A277 A305 I309 N454D268-T273 PolarHBondContact O-N 3.04Å; D268-T273 PolarHBondContact O-OG1 3.05Å; D269-T273 WeakPolarHBondContact O-CB 3.31Å; D269-T273 PolarHBondContact O-OG1 2.78Å; T273-V276 WeakPolarHBondContact O-CG1 3.14Å; T273-A277 WeakPolarHBondContact O-CB 3.42Å; T273-A277 PolarHBondContact O-N 3.23Å; T273-A305 HydrophobicContact CG2-CB 3.67Å; T273-I309 HydrophobicContact CG2-CD1 4.09Å; T273-I309 HydrophobicContact CG2-CG1 4.3Å; T273-N454 PolarHBondContact N-ND2 2.9Å; T273-N454 PolarHBondContact OG1-ND2 3.31Å
274A98.5Very high98.3Very high2 Ų24.2 Ų4.22%0.0172%0.023CC..Hα-helixtrans-58.7-49.3174.500000112.3I270 Q271 G272 A277 V278 G308 L312I270-A274 VanDerWaalsContact O-CB 3.24Å; I270-A274 WeakPolarHBondContact O-CB 3.31Å; I270-A274 PolarHBondContact O-N 2.7Å; Q271-A274 PolarHBondContact O-N 2.64Å; G272-A274 VanDerWaalsContact C-N 3.28Å; G272-A274 PolarHBondContact O-N 3.28Å; A274-A277 PolarHBondContact O-N 3.45Å; A274-V278 WeakPolarHBondContact O-CB 3.34Å; A274-V278 WeakPolarHBondContact O-CG2 3.32Å; A274-V278 PolarHBondContact O-N 2.8Å; A274-G308 VanDerWaalsContact CB-O 3.28Å; A274-G308 WeakPolarHBondContact CB-O 3.26Å; A274-L312 VanDerWaalsContact C-CD2 3.48Å; A274-L312 HydrophobicContact CB-CB 3.87Å; A274-L312 HydrophobicContact CB-CD2 3.84Å; A274-L312 HydrophobicContact CB-CG 4.48Å
275S98.8Very high98.3Very high0 Ų05 Ų50%03%0.027CC..Hα-helixtrans-61.9-47.4-178-1720000111.9Q271 G272 V278 A279 F478 A482Q271-S275 PolarHBondContact O-N 2.78Å; G272-S275 PolarHBondContact O-N 2.93Å; G272-S275 VanDerWaalsContact O-N 3.13Å; S275-V278 PolarHBondContact O-N 3.24Å; S275-A279 WeakPolarHBondContact O-CB 3.39Å; S275-A279 PolarHBondContact O-N 3.38Å; S275-F478 WeakPolarHBondContact CB-O 3.29Å; S275-F478 PolarHBondContact OG-O 2.96Å; S275-A482 WeakPolarHBondContact O-CB 3.26Å; S275-A482 PolarHBondContact OG-N 3.09Å
276V98.4Very high98.2Very high2 Ų29.2 Ų9.21%0.0124%0.043CC..Hα-helixtrans-67.4-41-179.670.80000111.7G272 T273 V278 A279 G280 Y456 V457 Y500G272-V276 PolarHBondContact O-N 2.66Å; T273-V276 WeakPolarHBondContact O-CG1 3.14Å; V276-V278 PolarHBondContact O-N 2.94Å; V276-A279 WeakPolarHBondContact O-CB 3.48Å; V276-A279 PolarHBondContact O-N 2.72Å; V276-G280 PolarHBondContact O-N 2.97Å; V276-Y456 HydrophobicContact CG2-CD2 4.4Å; V276-V457 HydrophobicContact CB-CG2 3.84Å; V276-Y500 HydrophobicContact CG2-CD1 4.22Å; V276-Y500 HydrophobicContact CG2-CE1 3.6Å; V276-Y500 VanDerWaalsContact O-CE1 3.3Å; V276-Y500 WeakPolarHBondContact O-CE1 3.29Å; V276-Y500 PolarHBondContact O-OH 3.36Å
277A98.6Very high98.2Very high0 Ų010.5 Ų10.50%05%0.05CC..Hα-helixtrans-64.1-42.3177.300000111.9T273 A274 A279 G280 L281 I309 L406T273-A277 WeakPolarHBondContact O-CB 3.42Å; T273-A277 PolarHBondContact O-N 3.23Å; A274-A277 PolarHBondContact O-N 3.45Å; A277-A279 VanDerWaalsContact C-N 3.31Å; A277-A279 PolarHBondContact O-N 3.22Å; A277-G280 PolarHBondContact O-N 3.44Å; A277-L281 WeakPolarHBondContact O-CG 3.42Å; A277-L281 PolarHBondContact O-N 3.5Å; A277-I309 HydrophobicContact CB-CB 4.38Å; A277-I309 HydrophobicContact CB-CD1 3.76Å; A277-I309 HydrophobicContact CB-CG1 3.67Å; A277-I309 HydrophobicContact CB-CG2 3.72Å; A277-L406 HydrophobicContact CB-CD1 4.23Å
278V98.9Very high98.2Very high1 Ų112 Ų121%0.0066%0.059CC..Hα-helixtrans-63.9-38.1174.5171.70000110.8A274 S275 V276 G280 L281 L282 L312 I313 A316 L479 A482A274-V278 WeakPolarHBondContact O-CB 3.34Å; A274-V278 WeakPolarHBondContact O-CG2 3.32Å; A274-V278 PolarHBondContact O-N 2.8Å; S275-V278 PolarHBondContact O-N 3.24Å; V276-V278 PolarHBondContact O-N 2.94Å; V278-G280 VanDerWaalsContact C-N 3.32Å; V278-G280 PolarHBondContact O-N 3.37Å; V278-L281 PolarHBondContact O-N 2.87Å; V278-L282 HydrophobicContact CG1-CD1 4.03Å; V278-L282 HydrophobicContact CG1-CG 4.12Å; V278-L282 VanDerWaalsContact O-CG 3.29Å; V278-L282 WeakPolarHBondContact O-CG 3.45Å; V278-L282 PolarHBondContact O-N 3.06Å; V278-L312 HydrophobicContact CB-CD2 4.12Å; V278-L312 HydrophobicContact CG2-CB 3.99Å; V278-L312 HydrophobicContact CG2-CD2 3.88Å; V278-L312 HydrophobicContact CG2-CG 4.02Å; V278-I313 HydrophobicContact CG2-CG1 3.77Å; V278-A316 HydrophobicContact CG1-CB 4.49Å; V278-L479 HydrophobicContact CG1-CD1 4.17Å; V278-A482 HydrophobicContact CB-CB 4.09Å; V278-A482 HydrophobicContact CG1-CB 3.91Å
279A98.9Very high98.2Very high0 Ų021 Ų210%010%0.098CC..Hα-helixtrans-58.8-44.8175.100000111.7S275 V276 A277 L282 A283 A482 I485 Y500S275-A279 WeakPolarHBondContact O-CB 3.39Å; S275-A279 PolarHBondContact O-N 3.38Å; V276-A279 WeakPolarHBondContact O-CB 3.48Å; V276-A279 PolarHBondContact O-N 2.72Å; A277-A279 VanDerWaalsContact C-N 3.31Å; A277-A279 PolarHBondContact O-N 3.22Å; A279-L282 PolarHBondContact O-N 3.32Å; A279-A283 PolarHBondContact O-N 2.97Å; A279-A482 HydrophobicContact CB-CB 4.07Å; A279-A482 WeakPolarHBondContact CB-O 3.17Å; A279-I485 HydrophobicContact CB-CB 3.84Å; A279-I485 HydrophobicContact CB-CD1 4.33Å; A279-I485 HydrophobicContact CB-CG2 3.79Å; A279-Y500 HydrophobicContact CB-CE1 4.32Å
280G98.7Very high98.3Very high0 Ų023.2 Ų23.20%011%0.11CC..Hα-helixtrans-62.7-40.4175.400000112.8V276 A277 V278 A283 A284 Y500V276-G280 PolarHBondContact O-N 2.97Å; A277-G280 PolarHBondContact O-N 3.44Å; V278-G280 VanDerWaalsContact C-N 3.32Å; V278-G280 PolarHBondContact O-N 3.37Å; G280-A283 PolarHBondContact O-N 3.09Å; G280-A284 WeakPolarHBondContact O-CB 3.46Å; G280-A284 PolarHBondContact O-N 3.33Å; G280-Y500 WeakPolarHBondContact CA-OH 3.13Å
281L98.8Very high98.3Very high3 Ų329.1 Ų29.12%0.01614%0.135CC..Hα-helixtrans-63.6-47174.5-71.2174.1000111.4A277 V278 A283 A284 L285 I297 I313 A375 I377 I402 F404A277-L281 WeakPolarHBondContact O-CG 3.42Å; A277-L281 PolarHBondContact O-N 3.5Å; V278-L281 PolarHBondContact O-N 2.87Å; L281-A283 VanDerWaalsContact C-N 3.28Å; L281-A283 PolarHBondContact O-N 2.68Å; L281-A284 CarbonylContact O-C 3.49Å; L281-A284 WeakPolarHBondContact O-CA 3.17Å; L281-A284 WeakPolarHBondContact O-CB 3.36Å; L281-A284 PolarHBondContact O-N 3.08Å; L281-L285 WeakPolarHBondContact O-CG 3.4Å; L281-L285 PolarHBondContact O-N 3.48Å; L281-I297 HydrophobicContact CD1-CD1 4.36Å; L281-I313 HydrophobicContact CD1-CD1 3.56Å; L281-I313 HydrophobicContact CD1-CG1 3.88Å; L281-A375 HydrophobicContact CD2-CB 4.35Å; L281-I377 HydrophobicContact CD1-CD1 4.31Å; L281-I402 HydrophobicContact CD2-CD1 4.33Å; L281-I402 HydrophobicContact CD2-CG2 3.99Å; L281-F404 HydrophobicContact CD2-CE2 3.89Å; L281-F404 HydrophobicContact CD2-CZ 4.04Å; L281-F404 HydrophobicContact CG-CE2 3.87Å; L281-F404 HydrophobicContact CG-CZ 4.31Å
282L98.8Very high98.3Very high37 Ų3728.8 Ų28.819%0.19413%0.134CC..Hα-helixtrans-60.1-38.6177.9-68176.2000111.9V278 A279 L285 A482 E483 A486V278-L282 HydrophobicContact CG1-CD1 4.03Å; V278-L282 HydrophobicContact CG1-CG 4.12Å; V278-L282 VanDerWaalsContact O-CG 3.29Å; V278-L282 WeakPolarHBondContact O-CG 3.45Å; V278-L282 PolarHBondContact O-N 3.06Å; A279-L282 PolarHBondContact O-N 3.32Å; L282-L285 HydrophobicContact CD2-CD1 4.29Å; L282-A482 HydrophobicContact CD1-CB 4.43Å; L282-E483 HydrophobicContact CD1-CG 3.79Å; L282-A486 HydrophobicContact CB-CB 3.77Å
283A98.8Very high98.3Very high0 Ų030.1 Ų30.10%014%0.143CC..Hα-helixtrans-65.9-41.7171.600000111.9A279 G280 L281 L285 R286 V489 L494 L499A279-A283 PolarHBondContact O-N 2.97Å; G280-A283 PolarHBondContact O-N 3.09Å; L281-A283 VanDerWaalsContact C-N 3.28Å; L281-A283 PolarHBondContact O-N 2.68Å; A283-L285 VanDerWaalsContact C-N 3.3Å; A283-L285 PolarHBondContact O-N 2.95Å; A283-R286 WeakPolarHBondContact O-CB 3.31Å; A283-R286 PolarHBondContact O-N 3.34Å; A283-V489 HydrophobicContact CB-CG2 4.35Å; A283-L494 HydrophobicContact CB-CD2 4.28Å; A283-L499 HydrophobicContact CB-CB 4.39Å; A283-L499 HydrophobicContact CB-CD2 4.03Å; A283-L499 VanDerWaalsContact CB-O 3.31Å; A283-L499 WeakPolarHBondContact CB-O 3.29Å
284A98.7Very high98.3Very high0 Ų033.4 Ų33.40%016%0.16CC..Hα-helixtrans-62.7-35.1178.100000112.5G280 L281 R286 I287 T288 I402 I429 L499G280-A284 WeakPolarHBondContact O-CB 3.46Å; G280-A284 PolarHBondContact O-N 3.33Å; L281-A284 CarbonylContact O-C 3.49Å; L281-A284 WeakPolarHBondContact O-CA 3.17Å; L281-A284 WeakPolarHBondContact O-CB 3.36Å; L281-A284 PolarHBondContact O-N 3.08Å; A284-R286 PolarHBondContact O-N 2.87Å; A284-I287 WeakPolarHBondContact O-CA 3.37Å; A284-I287 WeakPolarHBondContact O-CB 3.41Å; A284-I287 PolarHBondContact O-N 2.79Å; A284-T288 PolarHBondContact O-N 3.45Å; A284-T288 PolarHBondContact O-OG1 3.24Å; A284-I402 HydrophobicContact CB-CD1 3.82Å; A284-I402 HydrophobicContact CB-CG1 4.12Å; A284-I429 HydrophobicContact CB-CD1 4.41Å; A284-I429 HydrophobicContact CB-CG2 3.92Å; A284-L499 HydrophobicContact CB-CD1 4.31Å; A284-L499 HydrophobicContact CB-CD2 3.94Å
285L98.6Very high98.3Very high18 Ų1833.4 Ų33.49%0.09416%0.16CC..Hα-helixtrans-59.7-28176.9-67.5177.1000113.2L281 L282 A283 I287 T288 K289 N290 L292 Q295L281-L285 WeakPolarHBondContact O-CG 3.4Å; L281-L285 PolarHBondContact O-N 3.48Å; L282-L285 HydrophobicContact CD2-CD1 4.29Å; A283-L285 VanDerWaalsContact C-N 3.3Å; A283-L285 PolarHBondContact O-N 2.95Å; L285-I287 VanDerWaalsContact C-N 3.28Å; L285-I287 PolarHBondContact O-N 3.29Å; L285-T288 VanDerWaalsContact CA-OG1 3.3Å; L285-T288 WeakPolarHBondContact CA-OG1 3.11Å; L285-T288 PolarHBondContact O-OG1 3.11Å; L285-K289 WeakPolarHBondContact O-CA 3.22Å; L285-K289 PolarHBondContact O-N 2.95Å; L285-N290 WeakPolarHBondContact CD2-OD1 3.14Å; L285-L292 HydrophobicContact CD1-CB 3.74Å; L285-L292 HydrophobicContact CD1-CD1 4.24Å; L285-Q295 HydrophobicContact CD2-CG 4.06Å
286R98.6Very high98.3Very high89 Ų8935.2 Ų35.234%0.33617%0.17SC..Hα-helixtrans-71.5-24.4174.3-67.3165.256.2-161.1-3.7112.6A283 A284 A486 V489 D491 L494A283-R286 WeakPolarHBondContact O-CB 3.31Å; A283-R286 PolarHBondContact O-N 3.34Å; A284-R286 PolarHBondContact O-N 2.87Å; R286-A486 PolarHBondContact NH1-O 3.39Å; R286-V489 VanDerWaalsContact CZ-O 3.29Å; R286-V489 PolarHBondContact NH1-O 3.29Å; R286-V489 PolarHBondContact NH2-O 2.88Å; R286-D491 IonicContact CZ-OD1 2.85Å; R286-D491 IonicContact NE-OD1 3.78Å; R286-D491 IonicContact NH2-OD1 3.83Å; R286-D491 PolarHBondContact NH2-OD1 3.04Å; R286-L494 HydrophobicContact CB-CD1 3.62Å
287I98.4Very high98.3Very high27 Ų2735.1 Ų35.114%0.13817%0.17CC..Hα-helixtrans-82.4-47.7174.2-57173.8000110.2A284 L285 K289 I429 L494 L499A284-I287 WeakPolarHBondContact O-CA 3.37Å; A284-I287 WeakPolarHBondContact O-CB 3.41Å; A284-I287 PolarHBondContact O-N 2.79Å; L285-I287 VanDerWaalsContact C-N 3.28Å; L285-I287 PolarHBondContact O-N 3.29Å; I287-K289 VanDerWaalsContact C-N 3.28Å; I287-K289 PolarHBondContact O-N 2.82Å; I287-I429 HydrophobicContact CB-CD1 3.79Å; I287-I429 HydrophobicContact CD1-CD1 4.26Å; I287-I429 HydrophobicContact CD1-CG1 4.25Å; I287-I429 HydrophobicContact CD1-CG2 4.08Å; I287-I429 HydrophobicContact CG2-CD1 3.69Å; I287-I429 HydrophobicContact CG2-CG1 4.1Å; I287-L494 HydrophobicContact CD1-CB 4.23Å; I287-L494 HydrophobicContact CD1-CD2 4.06Å; I287-L494 HydrophobicContact CG1-CB 4.01Å; I287-L494 HydrophobicContact CG1-CD1 4.32Å; I287-L494 HydrophobicContact CG1-CD2 4.09Å; I287-L494 HydrophobicContact CG1-CG 4.37Å; I287-L499 HydrophobicContact CD1-CD2 3.99Å
288T98.1Very high98.3Very high31 Ų3135.1 Ų35.119%0.1917%0.17CC..Hα-helixtrans-74.3-18.3-178.855.20000113.1A284 L285 N290 R400 I402 I429A284-T288 PolarHBondContact O-N 3.45Å; A284-T288 PolarHBondContact O-OG1 3.24Å; L285-T288 VanDerWaalsContact CA-OG1 3.3Å; L285-T288 WeakPolarHBondContact CA-OG1 3.11Å; L285-T288 PolarHBondContact O-OG1 3.11Å; T288-N290 VanDerWaalsContact CB-OD1 3.26Å; T288-N290 WeakPolarHBondContact CB-OD1 3.25Å; T288-N290 PolarHBondContact O-N 2.87Å; T288-N290 PolarHBondContact OG1-OD1 3.3Å; T288-R400 HydrophobicContact CG2-CB 4.21Å; T288-I402 HydrophobicContact CG2-CD1 4.42Å; T288-I429 HydrophobicContact CG2-CD1 3.56Å
289K98Very high98.3Very high189 Ų18935 Ų3582%0.82217%0.169SC*.THydrogen-bonded Turntrans57.130.7178.9-60.2177.1178.8176.90113.6L285 I287L285-K289 WeakPolarHBondContact O-CA 3.22Å; L285-K289 PolarHBondContact O-N 2.95Å; I287-K289 VanDerWaalsContact C-N 3.28Å; I287-K289 PolarHBondContact O-N 2.82Å
290N96.6Very high98.3Very high57 Ų5735.6 Ų35.631%0.30517%0.172SC..SBendtrans-124.8177174.358.614.2000110.1L285 T288 D294 Q295L285-N290 WeakPolarHBondContact CD2-OD1 3.14Å; T288-N290 VanDerWaalsContact CB-OD1 3.26Å; T288-N290 WeakPolarHBondContact CB-OD1 3.25Å; T288-N290 PolarHBondContact O-N 2.87Å; T288-N290 PolarHBondContact OG1-OD1 3.3Å; N290-D294 HydrophobicContact CB-CB 4.25Å; N290-Q295 PolarHBondContact ND2-NE2 3.08Å; N290-Q295 PolarHBondContact OD1-NE2 3.18Å
291K97.7Very high98.2Very high131 Ų13136 Ų3657%0.5718%0.176SC*.  trans-93.1164-177.5-63.4179.9179.6-179.20111.7S293 D294 Q295K291-S293 WeakPolarHBondContact CB-OG 3.36Å; K291-S293 PolarHBondContact O-N 3.47Å; K291-D294 WeakPolarHBondContact CB-OD2 3.16Å; K291-D294 PolarHBondContact N-OD2 3.19Å; K291-D294 WeakPolarHBondContact O-CB 3.33Å; K291-D294 PolarHBondContact O-N 3.29Å; K291-Q295 PolarHBondContact O-NE2 2.92Å
292L98.1Very high98Very high1 Ų136.1 Ų36.11%0.00518%0.178CC..G310 helixtrans-62.8-38.6172.5-169.160.1000109.8L285 D294 Q295 I313 A316 M317 E320L285-L292 HydrophobicContact CD1-CB 3.74Å; L285-L292 HydrophobicContact CD1-CD1 4.24Å; L292-D294 PolarHBondContact O-N 2.95Å; L292-Q295 HydrophobicContact CD1-CG 4.26Å; L292-Q295 WeakPolarHBondContact O-CB 3.49Å; L292-Q295 WeakPolarHBondContact O-CG 3.42Å; L292-Q295 PolarHBondContact O-N 3.39Å; L292-I313 HydrophobicContact CD2-CG2 4.31Å; L292-A316 HydrophobicContact CD2-CB 3.4Å; L292-M317 HydrophobicContact CB-CG 4.4Å; L292-M317 HydrophobicContact CD2-CG 3.95Å; L292-M317 HydrophobicContact CG-CE 4.05Å; L292-M317 HydrophobicContact CG-CG 3.87Å; L292-M317 WeakPolarHBondContact O-CE 3.35Å; L292-E320 WeakPolarHBondContact CB-OE1 3.08Å; L292-E320 PolarHBondContact N-OE1 2.89Å; L292-E320 VanDerWaalsContact N-OE1 3.12Å; L292-E320 PolarHBondContact N-OE2 3.03Å
293S97.1Very high97.7Very high27 Ų2735.3 Ų35.319%0.18918%0.178CC..G310 helixtrans-59.2-12.3173.169.30000115K291 E320 K330K291-S293 WeakPolarHBondContact CB-OG 3.36Å; K291-S293 PolarHBondContact O-N 3.47Å; S293-E320 WeakPolarHBondContact CB-OE2 3.23Å; S293-E320 PolarHBondContact N-OE2 3.25Å; S293-K330 WeakPolarHBondContact O-CE 3.36Å; S293-K330 PolarHBondContact O-NZ 2.86Å
294D97.6Very high97.4Very high86 Ų8635.3 Ų35.346%0.4618%0.178SC..G310 helixtrans-91.3-13177-57.7-32.3000111.9N290 K291 L292N290-D294 HydrophobicContact CB-CB 4.25Å; K291-D294 WeakPolarHBondContact CB-OD2 3.16Å; K291-D294 PolarHBondContact N-OD2 3.19Å; K291-D294 WeakPolarHBondContact O-CB 3.33Å; K291-D294 PolarHBondContact O-N 3.29Å; L292-D294 PolarHBondContact O-N 2.95Å
295Q98.6Very high97.1Very high3 Ų336.1 Ų36.11%0.01419%0.185CC..  trans-78.1154.9-175.2-52.2-49-53.700112.8L285 N290 K291 L292 I297 K330 T374L285-Q295 HydrophobicContact CD2-CG 4.06Å; N290-Q295 PolarHBondContact ND2-NE2 3.08Å; N290-Q295 PolarHBondContact OD1-NE2 3.18Å; K291-Q295 PolarHBondContact O-NE2 2.92Å; L292-Q295 HydrophobicContact CD1-CG 4.26Å; L292-Q295 WeakPolarHBondContact O-CB 3.49Å; L292-Q295 WeakPolarHBondContact O-CG 3.42Å; L292-Q295 PolarHBondContact O-N 3.39Å; Q295-I297 HydrophobicContact CB-CD1 4.37Å; Q295-I297 HydrophobicContact CB-CG1 4.05Å; Q295-K330 WeakPolarHBondContact O-CD 3.42Å; Q295-K330 PolarHBondContact O-NZ 3.09Å; Q295-T374 WeakPolarHBondContact CA-OG1 3.38Å; Q295-T374 WeakPolarHBondContact CB-OG1 3.4Å; Q295-T374 VanDerWaalsContact OE1-CB 3.25Å; Q295-T374 PolarHBondContact OE1-OG1 3.14Å
296T98.8Very high97Very high37 Ų3735.3 Ų35.323%0.22718%0.18CC..  trans-124.5123.2161.9-62.50000107.2K330 I371 P373 T374 A375T296-K330 CarbonylContact C-O 3.5Å; T296-K330 WeakPolarHBondContact CA-O 2.93Å; T296-I371 HydrophobicContact CG2-CG2 3.96Å; T296-P373 HydrophobicContact CG2-CB 4.47Å; T296-P373 CarbonylContact O-C 3.09Å; T296-P373 WeakPolarHBondContact O-CA 3.39Å; T296-P373 WeakPolarHBondContact O-CB 3.49Å; T296-T374 PolarHBondContact N-OG1 2.81Å; T296-T374 PolarHBondContact O-N 3.39Å; T296-T374 PolarHBondContact O-OG1 3.15Å; T296-A375 PolarHBondContact O-N 3.28Å
297I98.9Very high96.9Very high0 Ų031.6 Ų31.60%017%0.167CC..EExtended strand (participates in β ladder)trans-117.4124-165.8-50.6-178.8000109L281 Q295 F299 I313 M317 K330 I331 W332 A375 I377L281-I297 HydrophobicContact CD1-CD1 4.36Å; Q295-I297 HydrophobicContact CB-CD1 4.37Å; Q295-I297 HydrophobicContact CB-CG1 4.05Å; I297-F299 HydrophobicContact CB-CE2 4.4Å; I297-F299 HydrophobicContact CG2-CD2 4.09Å; I297-F299 HydrophobicContact CG2-CE2 3.51Å; I297-F299 HydrophobicContact CG2-CZ 3.96Å; I297-I313 HydrophobicContact CD1-CD1 3.69Å; I297-I313 HydrophobicContact CD1-CG1 4.46Å; I297-I313 HydrophobicContact CD1-CG2 3.73Å; I297-M317 HydrophobicContact CD1-CE 4.37Å; I297-K330 PolarHBondContact N-O 3.03Å; I297-I331 CarbonylContact O-C 3.33Å; I297-I331 WeakPolarHBondContact O-CA 3.3Å; I297-W332 PolarHBondContact O-N 2.72Å; I297-A375 WeakPolarHBondContact CA-O 3.4Å; I297-A375 HydrophobicContact CG1-CB 4.26Å; I297-A375 HydrophobicContact CG2-CB 4.27Å; I297-I377 HydrophobicContact CG2-CD1 3.72Å; I297-I377 HydrophobicContact CG2-CG1 4.25Å
298L98.9Very high96.9Very high0 Ų030.6 Ų30.60%016%0.163CC..EExtended strand (participates in β ladder)trans-111.1125.2176.7-179.663.4000109.9W332 V334 L339 I367 V368 P373 A375 L376 I377L298-W332 WeakPolarHBondContact CA-O 3.37Å; L298-W332 HydrophobicContact CD1-CB 3.62Å; L298-V334 HydrophobicContact CD1-CG2 3.93Å; L298-L339 HydrophobicContact CD1-CD1 4.49Å; L298-I367 HydrophobicContact CD1-CG2 3.89Å; L298-I367 HydrophobicContact CD2-CG2 3.84Å; L298-V368 HydrophobicContact CD2-CG2 3.69Å; L298-P373 HydrophobicContact CB-CB 3.66Å; L298-P373 HydrophobicContact CB-CG 3.65Å; L298-P373 HydrophobicContact CD2-CG 3.94Å; L298-P373 HydrophobicContact CG-CG 4.46Å; L298-A375 PolarHBondContact N-O 3.11Å; L298-L376 HydrophobicContact CB-CD1 4.11Å; L298-L376 HydrophobicContact CD2-CD1 3.91Å; L298-L376 HydrophobicContact CG-CD1 4Å; L298-L376 WeakPolarHBondContact O-CA 3.18Å; L298-I377 PolarHBondContact O-N 2.81Å
299F98.9Very high96.9Very high0 Ų029.1 Ų29.10%015%0.154CC..EExtended strand (participates in β ladder)trans-100.8128.2175-71.8-91.7000111.2I297 A306 I309 A310 I313 I331 W332 L333 V334 I377I297-F299 HydrophobicContact CB-CE2 4.4Å; I297-F299 HydrophobicContact CG2-CD2 4.09Å; I297-F299 HydrophobicContact CG2-CE2 3.51Å; I297-F299 HydrophobicContact CG2-CZ 3.96Å; F299-A306 HydrophobicContact CB-CB 4.49Å; F299-A306 HydrophobicContact CD1-CB 4.14Å; F299-A306 HydrophobicContact CG-CB 4.48Å; F299-I309 HydrophobicContact CE1-CB 3.88Å; F299-I309 HydrophobicContact CE1-CD1 4.06Å; F299-I309 HydrophobicContact CE1-CG2 3.77Å; F299-I309 HydrophobicContact CZ-CB 4Å; F299-I309 HydrophobicContact CZ-CG2 3.62Å; F299-A310 HydrophobicContact CE2-CB 4.21Å; F299-I313 HydrophobicContact CE2-CD1 4.37Å; F299-I313 HydrophobicContact CZ-CD1 3.89Å; F299-I331 HydrophobicContact CD2-CG2 3.9Å; F299-I331 HydrophobicContact CE2-CG2 3.74Å; F299-W332 PolarHBondContact N-O 2.84Å; F299-L333 HydrophobicContact CB-CD2 4.31Å; F299-L333 HydrophobicContact CB-CG 4.22Å; F299-L333 HydrophobicContact CD2-CG 4.37Å; F299-V334 WeakPolarHBondContact O-CB 3.3Å; F299-V334 PolarHBondContact O-N 3.27Å; F299-I377 CarbonylContact C-O 3.59Å; F299-I377 VanDerWaalsContact CA-O 3.29Å; F299-I377 WeakPolarHBondContact CA-O 3.24Å; F299-I377 HydrophobicContact CD1-CB 3.73Å; F299-I377 HydrophobicContact CD1-CG2 3.84Å; F299-I377 HydrophobicContact CE1-CB 3.74Å; F299-I377 HydrophobicContact CE1-CD1 3.72Å; F299-I377 HydrophobicContact CE1-CG1 4.28Å; F299-I377 HydrophobicContact CE1-CG2 3.66Å; F299-I377 HydrophobicContact CG-CB 4.48Å; F299-I377 HydrophobicContact CZ-CB 4.47Å; F299-I377 HydrophobicContact CZ-CD1 3.72Å
300Q98.3Very high96.9Very high11 Ų1120.1 Ų20.15%0.05112%0.115CC..EExtended strand (participates in β ladder)trans-91.4107.1158.8-174.2-154.5-5.900108.7L364 I377 V379 A380 A385 F386Q300-L364 HydrophobicContact CB-CD2 4.3Å; Q300-L364 HydrophobicContact CG-CD2 3.97Å; Q300-I377 PolarHBondContact N-O 3.26Å; Q300-V379 PolarHBondContact O-N 3.41Å; Q300-A380 HydrophobicContact CG-CB 4.05Å; Q300-A380 PolarHBondContact O-N 3.08Å; Q300-A385 VanDerWaalsContact CD-CB 3.5Å; Q300-F386 HydrophobicContact CB-CE1 4.08Å
301G96.2Very high97Very high8 Ų820.7 Ų20.78%0.08212%0.116CC..  trans113.9143-169.800000110.6A306 V334G301-A306 WeakPolarHBondContact O-CB 3.48Å; G301-V334 CarbonylContact C-O 3.57Å; G301-V334 WeakPolarHBondContact CA-O 3.35Å; G301-V334 PolarHBondContact N-O 3.24Å
302A95.6Very high97.1Very high7 Ų714.6 Ų14.66%0.0589%0.089CC..  trans-13839.5176.200000110.6L333 V334 D335 I340 K351A302-L333 HydrophobicContact CB-CB 4.17Å; A302-L333 HydrophobicContact CB-CD2 4.12Å; A302-V334 PolarHBondContact N-O 3.43Å; A302-D335 HydrophobicContact CB-CB 3.96Å; A302-I340 HydrophobicContact CB-CD1 4.42Å; A302-I340 HydrophobicContact CB-CG1 4.44Å; A302-K351 HydrophobicContact CB-CD 4.32Å; A302-K351 HydrophobicContact CB-CG 4.44Å; A302-K351 WeakPolarHBondContact O-CE 3.21Å
303G92.4Very high97.1Very high19 Ų1914.5 Ų14.520%0.1969%0.089CC..SBendtrans-93.9-160175.900000112.7N249 A305 A306 L307N249-G303 WeakPolarHBondContact ND2-CA 3.43Å; G303-A305 PolarHBondContact O-N 2.9Å; G303-A306 PolarHBondContact O-N 2.96Å; G303-L307 WeakPolarHBondContact O-CB 3.39Å; G303-L307 WeakPolarHBondContact O-CG 3.17Å; G303-L307 PolarHBondContact O-N 3.23Å
304E90.7Very high97.2Very high1 Ų113.4 Ų13.41%0.0058%0.081CC..Hα-helixtrans-48.3-58.1178.9-72.4162.9-12000113.3R155 F247 N249 A252 F253 D269 I270 A306 L307 G308R155-E304 WeakPolarHBondContact CD-OE1 3.06Å; R155-E304 IonicContact CZ-OE1 2.9Å; R155-E304 IonicContact NE-OE1 2.6Å; R155-E304 IonicContact NH1-OE1 2.76Å; R155-E304 PolarHBondContact NH1-OE1 3.19Å; R155-E304 IonicContact NH1-OE2 3.61Å; F247-E304 VanDerWaalsContact O-OE1 3.11Å; N249-E304 WeakPolarHBondContact CA-OE1 3.37Å; N249-E304 HydrophobicContact CB-CG 4.13Å; N249-E304 VanDerWaalsContact CG-OE1 3.3Å; N249-E304 PolarHBondContact N-OE1 3.49Å; N249-E304 VanDerWaalsContact N-OE1 3.09Å; N249-E304 PolarHBondContact OD1-OE1 2.85Å; N249-E304 VanDerWaalsContact OD1-OE1 3.08Å; A252-E304 HydrophobicContact CB-CG 3.95Å; F253-E304 HydrophobicContact CD2-CG 4.35Å; F253-E304 HydrophobicContact CE2-CB 4.29Å; F253-E304 HydrophobicContact CE2-CG 3.92Å; D269-E304 WeakPolarHBondContact CB-OE2 3.1Å; I270-E304 HydrophobicContact CD1-CG 4.33Å; I270-E304 HydrophobicContact CG1-CB 3.73Å; I270-E304 HydrophobicContact CG1-CG 3.94Å; E304-A306 PolarHBondContact O-N 3.31Å; E304-L307 PolarHBondContact O-N 2.78Å; E304-G308 PolarHBondContact O-N 2.81Å
305A93Very high97.2Very high17 Ų1711.5 Ų11.514%0.147%0.07CC..Hα-helixtrans-56.8-53.8179.500000112T273 G303 L307 G308 I309 V379T273-A305 HydrophobicContact CG2-CB 3.67Å; G303-A305 PolarHBondContact O-N 2.9Å; A305-L307 PolarHBondContact O-N 3.14Å; A305-G308 PolarHBondContact O-N 2.91Å; A305-I309 WeakPolarHBondContact O-CB 3.49Å; A305-I309 WeakPolarHBondContact O-CD1 3.47Å; A305-I309 WeakPolarHBondContact O-CG1 3.35Å; A305-I309 PolarHBondContact O-N 2.9Å; A305-V379 HydrophobicContact CB-CB 4.05Å; A305-V379 HydrophobicContact CB-CG1 3.98Å; A305-V379 HydrophobicContact CB-CG2 4.42Å
306A97.1Very high97.2Very high0 Ų011.7 Ų11.70%07%0.072CC..Hα-helixtrans-58.5-47.7-176.300000112.6F299 G301 G303 E304 I309 A310 L333 V379F299-A306 HydrophobicContact CB-CB 4.49Å; F299-A306 HydrophobicContact CD1-CB 4.14Å; F299-A306 HydrophobicContact CG-CB 4.48Å; G301-A306 WeakPolarHBondContact O-CB 3.48Å; G303-A306 PolarHBondContact O-N 2.96Å; E304-A306 PolarHBondContact O-N 3.31Å; A306-I309 PolarHBondContact O-N 3.32Å; A306-A310 WeakPolarHBondContact O-CB 3.42Å; A306-A310 PolarHBondContact O-N 2.76Å; A306-L333 HydrophobicContact CB-CD2 3.97Å; A306-V379 HydrophobicContact CB-CG2 3.64Å
307L96.8Very high97.2Very high12 Ų129.9 Ų9.96%0.0636%0.061CC..Hα-helixtrans-70-37.4-178-69.9167.8000111.5F253 G303 E304 A305 H311 L333 E350 K351 F354F253-L307 HydrophobicContact CE1-CB 4.4Å; F253-L307 HydrophobicContact CE2-CB 4.3Å; F253-L307 HydrophobicContact CE2-CD1 3.82Å; F253-L307 HydrophobicContact CZ-CB 3.65Å; F253-L307 HydrophobicContact CZ-CD1 4Å; F253-L307 HydrophobicContact CZ-CG 4.49Å; G303-L307 WeakPolarHBondContact O-CB 3.39Å; G303-L307 WeakPolarHBondContact O-CG 3.17Å; G303-L307 PolarHBondContact O-N 3.23Å; E304-L307 PolarHBondContact O-N 2.78Å; A305-L307 PolarHBondContact O-N 3.14Å; L307-H311 VanDerWaalsContact O-CB 3.31Å; L307-H311 WeakPolarHBondContact O-CB 3.46Å; L307-H311 PolarHBondContact O-N 3.21Å; L307-L333 HydrophobicContact CD2-CD2 4.17Å; L307-E350 HydrophobicContact CD1-CB 3.79Å; L307-E350 HydrophobicContact CD2-CB 4.2Å; L307-K351 HydrophobicContact CD2-CG 4.39Å; L307-F354 HydrophobicContact CD2-CD2 4.28Å; L307-F354 HydrophobicContact CD2-CE2 4.29Å
308G97.5Very high97.2Very high5 Ų513.6 Ų13.65%0.0528%0.078CC..Hα-helixtrans-61.7-51.3172.600000112A274 E304 A305 A310 H311 L312A274-G308 VanDerWaalsContact CB-O 3.28Å; A274-G308 WeakPolarHBondContact CB-O 3.26Å; E304-G308 PolarHBondContact O-N 2.81Å; A305-G308 PolarHBondContact O-N 2.91Å; G308-A310 PolarHBondContact O-N 2.88Å; G308-H311 PolarHBondContact O-N 2.9Å; G308-L312 PolarHBondContact O-N 3.12Å
309I98.6Very high97.1Very high0 Ų019.4 Ų19.40%010%0.104CC..Hα-helixtrans-59.5-49.5178.1-59.5161.9000109.9T273 A277 F299 A305 A306 H311 L312 I313 I377 V379 L406T273-I309 HydrophobicContact CG2-CD1 4.09Å; T273-I309 HydrophobicContact CG2-CG1 4.3Å; A277-I309 HydrophobicContact CB-CB 4.38Å; A277-I309 HydrophobicContact CB-CD1 3.76Å; A277-I309 HydrophobicContact CB-CG1 3.67Å; A277-I309 HydrophobicContact CB-CG2 3.72Å; F299-I309 HydrophobicContact CE1-CB 3.88Å; F299-I309 HydrophobicContact CE1-CD1 4.06Å; F299-I309 HydrophobicContact CE1-CG2 3.77Å; F299-I309 HydrophobicContact CZ-CB 4Å; F299-I309 HydrophobicContact CZ-CG2 3.62Å; A305-I309 WeakPolarHBondContact O-CB 3.49Å; A305-I309 WeakPolarHBondContact O-CD1 3.47Å; A305-I309 WeakPolarHBondContact O-CG1 3.35Å; A305-I309 PolarHBondContact O-N 2.9Å; A306-I309 PolarHBondContact O-N 3.32Å; I309-H311 VanDerWaalsContact C-N 3.34Å; I309-H311 PolarHBondContact O-N 2.6Å; I309-L312 PolarHBondContact O-N 3.05Å; I309-I313 HydrophobicContact CG2-CD1 3.63Å; I309-I313 HydrophobicContact CG2-CG1 4.21Å; I309-I313 VanDerWaalsContact O-CG1 3.27Å; I309-I313 WeakPolarHBondContact O-CG1 3.46Å; I309-I313 PolarHBondContact O-N 3.47Å; I309-I377 HydrophobicContact CD1-CG2 4.45Å; I309-V379 HydrophobicContact CD1-CG1 4.17Å; I309-L406 HydrophobicContact CD1-CD1 4.22Å
310A98.6Very high97Very high0 Ų023.6 Ų23.60%012%0.123CC..Hα-helixtrans-57.7-44.5179.500000112.3F299 A306 G308 I313 V314 I331 F354F299-A310 HydrophobicContact CE2-CB 4.21Å; A306-A310 WeakPolarHBondContact O-CB 3.42Å; A306-A310 PolarHBondContact O-N 2.76Å; G308-A310 PolarHBondContact O-N 2.88Å; A310-I313 PolarHBondContact O-N 3.16Å; A310-V314 WeakPolarHBondContact O-CG2 3.34Å; A310-V314 PolarHBondContact O-N 3.01Å; A310-I331 HydrophobicContact CB-CD1 4.4Å; A310-I331 HydrophobicContact CB-CG2 3.88Å; A310-I331 WeakPolarHBondContact O-CD1 3.32Å; A310-F354 HydrophobicContact CB-CE1 3.97Å; A310-F354 HydrophobicContact CB-CE2 4.04Å; A310-F354 HydrophobicContact CB-CZ 3.58Å
311H98.2Very high97Very high69 Ų6926.1 Ų26.132%0.31915%0.152SC..Hα-helixtrans-61.2-44.4176.1174.775.1000112.2L307 G308 I309 V314 M315 D475L307-H311 VanDerWaalsContact O-CB 3.31Å; L307-H311 WeakPolarHBondContact O-CB 3.46Å; L307-H311 PolarHBondContact O-N 3.21Å; G308-H311 PolarHBondContact O-N 2.9Å; I309-H311 VanDerWaalsContact C-N 3.34Å; I309-H311 PolarHBondContact O-N 2.6Å; H311-V314 WeakPolarHBondContact O-CB 3.23Å; H311-V314 PolarHBondContact O-N 3.04Å; H311-M315 PolarHBondContact O-N 3.46Å; H311-M315 VanDerWaalsContact O-N 3.11Å; H311-D475 IonicContact CD2-OD2 3.72Å; H311-D475 IonicContact CE1-OD2 2.6Å; H311-D475 IonicContact NE2-OD2 2.74Å; H311-D475 PolarHBondContact NE2-OD2 3.41Å
312L98.6Very high97.1Very high3 Ų327.4 Ų27.42%0.01616%0.157CC..Hα-helixtrans-71.2-32.4-179.7-161.369.4000112.6A274 V278 G308 I309 M315 A316 D475 F478 L479A274-L312 VanDerWaalsContact C-CD2 3.48Å; A274-L312 HydrophobicContact CB-CB 3.87Å; A274-L312 HydrophobicContact CB-CD2 3.84Å; A274-L312 HydrophobicContact CB-CG 4.48Å; V278-L312 HydrophobicContact CB-CD2 4.12Å; V278-L312 HydrophobicContact CG2-CB 3.99Å; V278-L312 HydrophobicContact CG2-CD2 3.88Å; V278-L312 HydrophobicContact CG2-CG 4.02Å; G308-L312 PolarHBondContact O-N 3.12Å; I309-L312 PolarHBondContact O-N 3.05Å; L312-M315 HydrophobicContact CD1-SD 4.48Å; L312-M315 PolarHBondContact O-N 3.34Å; L312-A316 WeakPolarHBondContact O-CB 3.43Å; L312-A316 PolarHBondContact O-N 2.89Å; L312-D475 HydrophobicContact CD1-CB 4.44Å; L312-F478 HydrophobicContact CD1-CB 4.31Å; L312-F478 HydrophobicContact CD2-CB 4.23Å; L312-L479 HydrophobicContact CD1-CB 3.96Å
313I98.8Very high97.2Very high0 Ų030.6 Ų30.60%018%0.177CC..Hα-helixtrans-62.5-44.2170.6-70.5167.4000110.7V278 L281 L292 I297 F299 I309 A310 M315 A316 M317 I331V278-I313 HydrophobicContact CG2-CG1 3.77Å; L281-I313 HydrophobicContact CD1-CD1 3.56Å; L281-I313 HydrophobicContact CD1-CG1 3.88Å; L292-I313 HydrophobicContact CD2-CG2 4.31Å; I297-I313 HydrophobicContact CD1-CD1 3.69Å; I297-I313 HydrophobicContact CD1-CG1 4.46Å; I297-I313 HydrophobicContact CD1-CG2 3.73Å; F299-I313 HydrophobicContact CE2-CD1 4.37Å; F299-I313 HydrophobicContact CZ-CD1 3.89Å; I309-I313 HydrophobicContact CG2-CD1 3.63Å; I309-I313 HydrophobicContact CG2-CG1 4.21Å; I309-I313 VanDerWaalsContact O-CG1 3.27Å; I309-I313 WeakPolarHBondContact O-CG1 3.46Å; I309-I313 PolarHBondContact O-N 3.47Å; A310-I313 PolarHBondContact O-N 3.16Å; I313-M315 VanDerWaalsContact C-N 3.3Å; I313-M315 PolarHBondContact O-N 3.48Å; I313-A316 WeakPolarHBondContact O-CB 3.44Å; I313-A316 PolarHBondContact O-N 2.81Å; I313-A316 VanDerWaalsContact O-N 3.15Å; I313-M317 HydrophobicContact CG2-CE 3.69Å; I313-M317 HydrophobicContact CG2-CG 4.48Å; I313-M317 HydrophobicContact CG2-SD 4.32Å; I313-M317 WeakPolarHBondContact O-CG 3.34Å; I313-M317 PolarHBondContact O-N 2.77Å; I313-I331 HydrophobicContact CB-CD1 4.17Å; I313-I331 HydrophobicContact CG2-CD1 3.83Å; I313-I331 HydrophobicContact CG2-CG1 4.38Å
314V98.8Very high97.4Very high4 Ų434.8 Ų34.82%0.02419%0.19CC..Hα-helixtrans-56.7-48175.6168.70000110.1A310 H311 A316 M317 E318 K324 A327 I328 I331 F354A310-V314 WeakPolarHBondContact O-CG2 3.34Å; A310-V314 PolarHBondContact O-N 3.01Å; H311-V314 WeakPolarHBondContact O-CB 3.23Å; H311-V314 PolarHBondContact O-N 3.04Å; V314-A316 VanDerWaalsContact C-N 3.31Å; V314-A316 PolarHBondContact O-N 3.36Å; V314-M317 PolarHBondContact O-N 2.68Å; V314-E318 HydrophobicContact CG1-CG 4.46Å; V314-E318 WeakPolarHBondContact O-CG 3.41Å; V314-E318 PolarHBondContact O-N 2.98Å; V314-K324 HydrophobicContact CG1-CG 3.75Å; V314-A327 HydrophobicContact CB-CB 4.42Å; V314-A327 HydrophobicContact CG1-CB 4.07Å; V314-A327 HydrophobicContact CG2-CB 4.34Å; V314-I328 HydrophobicContact CG1-CG1 4.43Å; V314-I328 HydrophobicContact CG2-CG1 3.95Å; V314-I331 HydrophobicContact CG2-CD1 3.59Å; V314-F354 HydrophobicContact CG2-CE1 4.06Å; V314-F354 HydrophobicContact CG2-CZ 4.49Å
315M98.5Very high97.7Very high45 Ų4542.3 Ų42.322%0.22223%0.225CC..Hα-helixtrans-62-37.2177-71.1-175.360.400113.1H311 L312 I313 E318 K319 D475 L479H311-M315 PolarHBondContact O-N 3.46Å; H311-M315 VanDerWaalsContact O-N 3.11Å; L312-M315 HydrophobicContact CD1-SD 4.48Å; L312-M315 PolarHBondContact O-N 3.34Å; I313-M315 VanDerWaalsContact C-N 3.3Å; I313-M315 PolarHBondContact O-N 3.48Å; M315-E318 PolarHBondContact O-N 3.19Å; M315-K319 PolarHBondContact O-N 3.25Å; M315-D475 HydrophobicContact CE-CB 3.74Å; M315-D475 HydrophobicContact SD-CB 3.43Å; M315-D475 WeakPolarHBondContact SD-CB 3.24Å; M315-L479 HydrophobicContact CB-CD2 4.44Å
316A98.6Very high98Very high7 Ų747.6 Ų47.66%0.05825%0.245CC..Hα-helixtrans-65.3-42.1175.600000111.6V278 L292 L312 I313 V314 K319 E320 L479V278-A316 HydrophobicContact CG1-CB 4.49Å; L292-A316 HydrophobicContact CD2-CB 3.4Å; L312-A316 WeakPolarHBondContact O-CB 3.43Å; L312-A316 PolarHBondContact O-N 2.89Å; I313-A316 WeakPolarHBondContact O-CB 3.44Å; I313-A316 PolarHBondContact O-N 2.81Å; I313-A316 VanDerWaalsContact O-N 3.15Å; V314-A316 VanDerWaalsContact C-N 3.31Å; V314-A316 PolarHBondContact O-N 3.36Å; A316-K319 WeakPolarHBondContact O-CB 3.44Å; A316-K319 PolarHBondContact O-N 3.04Å; A316-E320 PolarHBondContact O-N 2.81Å; A316-E320 VanDerWaalsContact O-N 3.13Å; A316-L479 HydrophobicContact CB-CD1 3.68Å
317M98.6Very high98Very high0 Ų047.6 Ų47.60%025%0.245CC..Hα-helixtrans-66.2-36.9173.6-68.8179.5-178.600112.2L292 I297 I313 V314 K319 E320 G321 L322 A327 K330L292-M317 HydrophobicContact CB-CG 4.4Å; L292-M317 HydrophobicContact CD2-CG 3.95Å; L292-M317 HydrophobicContact CG-CE 4.05Å; L292-M317 HydrophobicContact CG-CG 3.87Å; L292-M317 WeakPolarHBondContact O-CE 3.35Å; I297-M317 HydrophobicContact CD1-CE 4.37Å; I313-M317 HydrophobicContact CG2-CE 3.69Å; I313-M317 HydrophobicContact CG2-CG 4.48Å; I313-M317 HydrophobicContact CG2-SD 4.32Å; I313-M317 WeakPolarHBondContact O-CG 3.34Å; I313-M317 PolarHBondContact O-N 2.77Å; V314-M317 PolarHBondContact O-N 2.68Å; M317-K319 VanDerWaalsContact C-N 3.3Å; M317-K319 PolarHBondContact O-N 3.39Å; M317-E320 WeakPolarHBondContact O-CB 3.23Å; M317-E320 PolarHBondContact O-N 3.19Å; M317-E320 VanDerWaalsContact O-N 3.16Å; M317-G321 PolarHBondContact O-N 3.29Å; M317-L322 HydrophobicContact CB-CB 4.27Å; M317-L322 HydrophobicContact CB-CD2 4.22Å; M317-L322 WeakPolarHBondContact O-CB 3.49Å; M317-L322 PolarHBondContact O-N 2.98Å; M317-L322 HydrophobicContact SD-CD2 4.14Å; M317-A327 HydrophobicContact CB-CB 3.75Å; M317-A327 HydrophobicContact CG-CB 4.38Å; M317-A327 HydrophobicContact SD-CB 3.71Å; M317-K330 HydrophobicContact CE-CB 4.06Å; M317-K330 HydrophobicContact CE-CD 4.05Å; M317-K330 HydrophobicContact SD-CB 4.41Å; M317-K330 HydrophobicContact SD-CD 4.03Å
318E98.4Very high98.1Very high77 Ų7748.6 Ų48.636%0.3625%0.25SS..Hα-helixtrans-61.9-38.9172.4-73.4-179.5116.800111.6V314 M315 E320 G321 L322 K324V314-E318 HydrophobicContact CG1-CG 4.46Å; V314-E318 WeakPolarHBondContact O-CG 3.41Å; V314-E318 PolarHBondContact O-N 2.98Å; M315-E318 PolarHBondContact O-N 3.19Å; E318-E320 VanDerWaalsContact C-N 3.29Å; E318-E320 PolarHBondContact O-N 3.44Å; E318-G321 WeakPolarHBondContact O-CA 3.39Å; E318-G321 PolarHBondContact O-N 3.44Å; E318-L322 VanDerWaalsContact CA-O 3.3Å; E318-L322 WeakPolarHBondContact CA-O 3.12Å; E318-K324 HydrophobicContact CG-CB 4.42Å; E318-K324 VanDerWaalsContact OE1-CB 3.24Å; E318-K324 WeakPolarHBondContact OE1-CB 3.24Å
319K97.7Very high98.2Very high123 Ų12355.5 Ų55.554%0.53528%0.279SS..Hα-helixtrans-64.8-30.8174.1-170176.3178.6178.30112.6M315 A316 M317 G321 L479 E483M315-K319 PolarHBondContact O-N 3.25Å; A316-K319 WeakPolarHBondContact O-CB 3.44Å; A316-K319 PolarHBondContact O-N 3.04Å; M317-K319 VanDerWaalsContact C-N 3.3Å; M317-K319 PolarHBondContact O-N 3.39Å; K319-G321 PolarHBondContact O-N 3.44Å; K319-L479 HydrophobicContact CB-CD2 4.44Å; K319-L479 HydrophobicContact CD-CD2 3.94Å; K319-E483 WeakPolarHBondContact CD-OE1 3.32Å; K319-E483 WeakPolarHBondContact CE-OE1 3.36Å; K319-E483 IonicContact NZ-OE1 2.68Å; K319-E483 PolarHBondContact NZ-OE1 3.11Å; K319-E483 IonicContact NZ-OE2 3.53Å; K319-E483 PolarHBondContact NZ-OE2 3.01Å
320E96.8Very high98.2Very high88 Ų8857.7 Ų57.741%0.41129%0.288SS..THydrogen-bonded Turntrans-73.4-7.8169.7-67.5-175163.300113.4L292 S293 A316 M317 E318L292-E320 WeakPolarHBondContact CB-OE1 3.08Å; L292-E320 PolarHBondContact N-OE1 2.89Å; L292-E320 VanDerWaalsContact N-OE1 3.12Å; L292-E320 PolarHBondContact N-OE2 3.03Å; S293-E320 WeakPolarHBondContact CB-OE2 3.23Å; S293-E320 PolarHBondContact N-OE2 3.25Å; A316-E320 PolarHBondContact O-N 2.81Å; A316-E320 VanDerWaalsContact O-N 3.13Å; M317-E320 WeakPolarHBondContact O-CB 3.23Å; M317-E320 PolarHBondContact O-N 3.19Å; M317-E320 VanDerWaalsContact O-N 3.16Å; E318-E320 VanDerWaalsContact C-N 3.29Å; E318-E320 PolarHBondContact O-N 3.44Å
321G97.4Very high98.2Very high64 Ų6457.7 Ų57.766%0.6629%0.288SS*.THydrogen-bonded Turntrans98.35.8179.600000114.8M317 E318 K319M317-G321 PolarHBondContact O-N 3.29Å; E318-G321 WeakPolarHBondContact O-CA 3.39Å; E318-G321 PolarHBondContact O-N 3.44Å; K319-G321 PolarHBondContact O-N 3.44Å
322L97.9Very high98.2Very high34 Ų3456.1 Ų56.118%0.17828%0.279CS..  trans-80.8124.8177-170.168.9000110.4M317 E318 K326 A327 K330M317-L322 HydrophobicContact CB-CB 4.27Å; M317-L322 HydrophobicContact CB-CD2 4.22Å; M317-L322 WeakPolarHBondContact O-CB 3.49Å; M317-L322 PolarHBondContact O-N 2.98Å; M317-L322 HydrophobicContact SD-CD2 4.14Å; E318-L322 VanDerWaalsContact CA-O 3.3Å; E318-L322 WeakPolarHBondContact CA-O 3.12Å; L322-K326 HydrophobicContact CD1-CB 3.83Å; L322-K326 HydrophobicContact CD1-CD 4.07Å; L322-K326 HydrophobicContact CD2-CB 4.26Å; L322-K326 HydrophobicContact CG-CB 3.91Å; L322-A327 HydrophobicContact CD2-CB 4.08Å; L322-K330 HydrophobicContact CD2-CD 4.07Å
323P98.1Very high98.2Very high75 Ų7556 Ų5649%0.48728%0.279SS..  trans-58.7143.4177.6-24.933.9000112.6E325 K326 A327P323-E325 VanDerWaalsContact C-N 3.27Å; P323-E325 PolarHBondContact O-N 3.2Å; P323-E325 VanDerWaalsContact O-N 3.11Å; P323-K326 WeakPolarHBondContact O-CA 3.38Å; P323-K326 WeakPolarHBondContact O-CB 3.42Å; P323-K326 PolarHBondContact O-N 3.07Å; P323-A327 PolarHBondContact O-N 3.12Å
324K97.8Very high98.2Very high106 Ų10656.5 Ų56.546%0.46128%0.282SS..Hα-helixtrans-43.9-48.5-178.5-161.8172.3179.81680114.6V314 E318 K326 A327 I328V314-K324 HydrophobicContact CG1-CG 3.75Å; E318-K324 HydrophobicContact CG-CB 4.42Å; E318-K324 VanDerWaalsContact OE1-CB 3.24Å; E318-K324 WeakPolarHBondContact OE1-CB 3.24Å; K324-K326 VanDerWaalsContact C-N 3.26Å; K324-K326 PolarHBondContact O-N 3.34Å; K324-A327 PolarHBondContact O-N 3.03Å; K324-A327 VanDerWaalsContact O-N 3.17Å; K324-I328 HydrophobicContact CG-CD1 4.01Å; K324-I328 WeakPolarHBondContact O-CG1 3.46Å; K324-I328 PolarHBondContact O-N 3.39Å
325E97.1Very high98.1Very high160 Ų16057.3 Ų57.375%0.74829%0.286SS*.Hα-helixtrans-62.1-33.6-177.7-62.6177.6-177.600112.5P323 K329P323-E325 VanDerWaalsContact C-N 3.27Å; P323-E325 PolarHBondContact O-N 3.2Å; P323-E325 VanDerWaalsContact O-N 3.11Å; E325-K329 WeakPolarHBondContact O-CG 3.35Å; E325-K329 PolarHBondContact O-N 3.06Å
326K98.1Very high97.9Very high128 Ų12860.5 Ų60.556%0.55731%0.313SS*.Hα-helixtrans-79-35.3175.9-67.6-172.7178.7-179.50111.7L322 P323 K324 K329L322-K326 HydrophobicContact CD1-CB 3.83Å; L322-K326 HydrophobicContact CD1-CD 4.07Å; L322-K326 HydrophobicContact CD2-CB 4.26Å; L322-K326 HydrophobicContact CG-CB 3.91Å; P323-K326 WeakPolarHBondContact O-CA 3.38Å; P323-K326 WeakPolarHBondContact O-CB 3.42Å; P323-K326 PolarHBondContact O-N 3.07Å; K324-K326 VanDerWaalsContact C-N 3.26Å; K324-K326 PolarHBondContact O-N 3.34Å; K326-K329 PolarHBondContact O-N 3.32Å
327A98.3Very high97.8Very high0 Ų065.4 Ų65.40%033%0.333CS..Hα-helixtrans-64-44.2174.600000111.5V314 M317 L322 P323 K324 K329 K330V314-A327 HydrophobicContact CB-CB 4.42Å; V314-A327 HydrophobicContact CG1-CB 4.07Å; V314-A327 HydrophobicContact CG2-CB 4.34Å; M317-A327 HydrophobicContact CB-CB 3.75Å; M317-A327 HydrophobicContact CG-CB 4.38Å; M317-A327 HydrophobicContact SD-CB 3.71Å; L322-A327 HydrophobicContact CD2-CB 4.08Å; P323-A327 PolarHBondContact O-N 3.12Å; K324-A327 PolarHBondContact O-N 3.03Å; K324-A327 VanDerWaalsContact O-N 3.17Å; A327-K329 VanDerWaalsContact C-N 3.3Å; A327-K329 PolarHBondContact O-N 3.35Å; A327-K330 WeakPolarHBondContact O-CB 3.47Å; A327-K330 PolarHBondContact O-N 2.93Å; A327-K330 VanDerWaalsContact O-N 3.08Å
328I98.4Very high97.7Very high33 Ų3365.5 Ų65.517%0.16933%0.334CS..Hα-helixtrans-56.7-42.5176.4-75.3169.8000111.5V314 K324 K330 I331 K353 F354 H356V314-I328 HydrophobicContact CG1-CG1 4.43Å; V314-I328 HydrophobicContact CG2-CG1 3.95Å; K324-I328 HydrophobicContact CG-CD1 4.01Å; K324-I328 WeakPolarHBondContact O-CG1 3.46Å; K324-I328 PolarHBondContact O-N 3.39Å; I328-K330 PolarHBondContact O-N 3.46Å; I328-I331 PolarHBondContact O-N 3.04Å; I328-I331 VanDerWaalsContact O-N 3.08Å; I328-K353 WeakPolarHBondContact CG2-O 3.29Å; I328-F354 HydrophobicContact CG1-CE1 4.34Å; I328-F354 HydrophobicContact CG2-CD1 4.17Å; I328-H356 PolarHBondContact O-CE1 3.26Å; I328-H356 PolarHBondContact O-NE2 2.86Å
329K98.3Very high97.7Very high149 Ų14961.8 Ų61.865%0.64832%0.317SS*.THydrogen-bonded Turntrans-62-11.3179-74.9179.8179.6-174.70114.8E325 K326 A327E325-K329 WeakPolarHBondContact O-CG 3.35Å; E325-K329 PolarHBondContact O-N 3.06Å; K326-K329 PolarHBondContact O-N 3.32Å; A327-K329 VanDerWaalsContact C-N 3.3Å; A327-K329 PolarHBondContact O-N 3.35Å
330K98.6Very high97.7Very high47 Ų4756 Ų5620%0.20429%0.291CS..THydrogen-bonded Turntrans-92.8-4.2178.1-70.1177.6157.5-82.20113.5S293 Q295 T296 I297 M317 L322 A327 I328S293-K330 WeakPolarHBondContact O-CE 3.36Å; S293-K330 PolarHBondContact O-NZ 2.86Å; Q295-K330 WeakPolarHBondContact O-CD 3.42Å; Q295-K330 PolarHBondContact O-NZ 3.09Å; T296-K330 CarbonylContact C-O 3.5Å; T296-K330 WeakPolarHBondContact CA-O 2.93Å; I297-K330 PolarHBondContact N-O 3.03Å; M317-K330 HydrophobicContact CE-CB 4.06Å; M317-K330 HydrophobicContact CE-CD 4.05Å; M317-K330 HydrophobicContact SD-CB 4.41Å; M317-K330 HydrophobicContact SD-CD 4.03Å; L322-K330 HydrophobicContact CD2-CD 4.07Å; A327-K330 WeakPolarHBondContact O-CB 3.47Å; A327-K330 PolarHBondContact O-N 2.93Å; A327-K330 VanDerWaalsContact O-N 3.08Å; I328-K330 PolarHBondContact O-N 3.46Å
331I98.8Very high97.8Very high0 Ų051.9 Ų51.90%027%0.272CS..EExtended strand (participates in β ladder)trans-119.7124.1-172.3-61.3165.8000110.1I297 F299 A310 I313 V314 I328 L333 F354 H356I297-I331 CarbonylContact O-C 3.33Å; I297-I331 WeakPolarHBondContact O-CA 3.3Å; F299-I331 HydrophobicContact CD2-CG2 3.9Å; F299-I331 HydrophobicContact CE2-CG2 3.74Å; A310-I331 HydrophobicContact CB-CD1 4.4Å; A310-I331 HydrophobicContact CB-CG2 3.88Å; A310-I331 WeakPolarHBondContact O-CD1 3.32Å; I313-I331 HydrophobicContact CB-CD1 4.17Å; I313-I331 HydrophobicContact CG2-CD1 3.83Å; I313-I331 HydrophobicContact CG2-CG1 4.38Å; V314-I331 HydrophobicContact CG2-CD1 3.59Å; I328-I331 PolarHBondContact O-N 3.04Å; I328-I331 VanDerWaalsContact O-N 3.08Å; I331-L333 HydrophobicContact CG2-CD1 4.21Å; I331-F354 HydrophobicContact CB-CD1 4.08Å; I331-F354 HydrophobicContact CB-CE1 4.22Å; I331-F354 HydrophobicContact CD1-CE1 4.02Å; I331-F354 HydrophobicContact CG2-CD1 4.04Å; I331-F354 HydrophobicContact CG2-CE1 4.17Å; I331-H356 PolarHBondContact O-NE2 3.08Å
332W98.9Very high97.8Very high35 Ų3555.7 Ų55.713%0.13327%0.271CS..EExtended strand (participates in β ladder)trans-118.3139.2179.5-62.284000109.5I297 L298 F299 L339 H356 H358 I371I297-W332 PolarHBondContact O-N 2.72Å; L298-W332 WeakPolarHBondContact CA-O 3.37Å; L298-W332 HydrophobicContact CD1-CB 3.62Å; F299-W332 PolarHBondContact N-O 2.84Å; W332-L339 HydrophobicContact CB-CD1 4.49Å; W332-L339 HydrophobicContact CE3-CD1 4.14Å; W332-L339 HydrophobicContact CE3-CD2 4.27Å; W332-L339 HydrophobicContact CE3-CG 4.48Å; W332-L339 HydrophobicContact CZ3-CD2 4.37Å; W332-H356 AromaticContact CD2-CD2 3.6Å; W332-H356 AromaticContact CE2-CD2 3.72Å; W332-H356 HydrophobicContact CE3-CB 4.49Å; W332-H356 AromaticContact CE3-CD2 3.5Å; W332-H356 HydrophobicContact CH2-CB 3.61Å; W332-H356 AromaticContact CH2-CD2 3.7Å; W332-H356 AromaticContact CH2-CG 3.91Å; W332-H356 HydrophobicContact CZ2-CB 4.33Å; W332-H356 AromaticContact CZ2-CD2 3.78Å; W332-H356 HydrophobicContact CZ3-CB 3.71Å; W332-H356 AromaticContact CZ3-CD2 3.56Å; W332-H358 HydrophobicContact CH2-CB 4.15Å; W332-H358 AromaticContact CH2-CD2 3.94Å; W332-H358 HydrophobicContact CZ3-CB 3.87Å; W332-I371 HydrophobicContact CB-CG2 4.47Å; W332-I371 HydrophobicContact CD2-CD1 3.71Å; W332-I371 HydrophobicContact CD2-CG1 4.35Å; W332-I371 HydrophobicContact CD2-CG2 4.32Å; W332-I371 HydrophobicContact CE3-CD1 3.71Å; W332-I371 HydrophobicContact CG-CD1 4.33Å; W332-I371 HydrophobicContact CG-CG1 4.49Å; W332-I371 HydrophobicContact CG-CG2 3.89Å; W332-I371 HydrophobicContact CH2-CD1 4.09Å; W332-I371 HydrophobicContact CZ2-CD1 4.1Å; W332-I371 HydrophobicContact CZ3-CD1 3.9Å
333L98.6Very high97.5Very high1 Ų157.4 Ų57.41%0.00530%0.297CS..EExtended strand (participates in β ladder)trans-123.8148.1179-60.8105.4000111.1F299 A302 A306 L307 I331 I340 F354F299-L333 HydrophobicContact CB-CD2 4.31Å; F299-L333 HydrophobicContact CB-CG 4.22Å; F299-L333 HydrophobicContact CD2-CG 4.37Å; A302-L333 HydrophobicContact CB-CB 4.17Å; A302-L333 HydrophobicContact CB-CD2 4.12Å; A306-L333 HydrophobicContact CB-CD2 3.97Å; L307-L333 HydrophobicContact CD2-CD2 4.17Å; I331-L333 HydrophobicContact CG2-CD1 4.21Å; L333-I340 HydrophobicContact CB-CB 4.34Å; L333-I340 HydrophobicContact CB-CG1 3.7Å; L333-I340 WeakPolarHBondContact O-CG1 3.43Å; L333-I340 PolarHBondContact O-N 3.37Å; L333-F354 HydrophobicContact CD1-CB 3.22Å; L333-F354 HydrophobicContact CD1-CD1 4.12Å; L333-F354 HydrophobicContact CD1-CD2 3.74Å; L333-F354 HydrophobicContact CD1-CG 3.45Å; L333-F354 VanDerWaalsContact CD1-CG 3.45Å
334V98.3Very high97.4Very high10 Ų1054.5 Ų54.56%0.06128%0.276CS..EExtended strand (participates in β ladder)trans-126.1134.4175.1-175.90000108.4L298 F299 G301 A302 G338 L339 L364 I367L298-V334 HydrophobicContact CD1-CG2 3.93Å; F299-V334 WeakPolarHBondContact O-CB 3.3Å; F299-V334 PolarHBondContact O-N 3.27Å; G301-V334 CarbonylContact C-O 3.57Å; G301-V334 WeakPolarHBondContact CA-O 3.35Å; G301-V334 PolarHBondContact N-O 3.24Å; A302-V334 PolarHBondContact N-O 3.43Å; V334-G338 WeakPolarHBondContact CA-O 3.34Å; V334-L339 HydrophobicContact CG2-CD1 3.95Å; V334-L364 HydrophobicContact CG2-CD1 4.24Å; V334-I367 HydrophobicContact CG1-CD1 4.18Å; V334-I367 HydrophobicContact CG2-CD1 3.96Å; V334-I367 HydrophobicContact CG2-CG2 4.18Å
335D96.3Very high97.1Very high22 Ų2252.9 Ų52.912%0.11828%0.282CS..EExtended strand (participates in β ladder)trans-121.1-172169.769.611.6000111.8A302 K337 G338 I340 R344 K351A302-D335 HydrophobicContact CB-CB 3.96Å; D335-K337 PolarHBondContact O-N 3.45Å; D335-K337 WeakPolarHBondContact OD1-CB 3.45Å; D335-K337 PolarHBondContact OD1-N 2.97Å; D335-G338 PolarHBondContact N-O 3.23Å; D335-G338 PolarHBondContact O-N 2.84Å; D335-G338 PolarHBondContact OD1-N 3.42Å; D335-I340 HydrophobicContact CB-CD1 4.33Å; D335-I340 WeakPolarHBondContact OD2-CD1 3.42Å; D335-R344 VanDerWaalsContact CG-NH2 3.31Å; D335-R344 IonicContact OD1-CZ 3.48Å; D335-R344 IonicContact OD1-NH1 2.99Å; D335-R344 PolarHBondContact OD1-NH1 3.39Å; D335-R344 IonicContact OD1-NH2 3.11Å; D335-R344 PolarHBondContact OD1-NH2 2.72Å; D335-R344 VanDerWaalsContact OD1-NH2 3.11Å; D335-R344 IonicContact OD2-CZ 2.65Å; D335-R344 IonicContact OD2-NH2 2.64Å; D335-R344 PolarHBondContact OD2-NH2 3.27Å; D335-K351 IonicContact OD2-NZ 3.17Å; D335-K351 PolarHBondContact OD2-NZ 3.09Å
336S94.5Very high96.8Very high111 Ų11148.9 Ų48.978%0.77627%0.272SS*.THydrogen-bonded Turntrans-59.3-17.5-179.357.10000114.2
337K96.3Very high96.5Very high110 Ų11044.2 Ų44.248%0.47825%0.253SS..THydrogen-bonded Turntrans-93.3-11.9176-57.3-170.8-179.3810113D335 S346D335-K337 PolarHBondContact O-N 3.45Å; D335-K337 WeakPolarHBondContact OD1-CB 3.45Å; D335-K337 PolarHBondContact OD1-N 2.97Å; K337-S346 WeakPolarHBondContact CE-OG 3.44Å
338G97.1Very high96.1Very high2 Ų247 Ų472%0.02127%0.27CS..EExtended strand (participates in β ladder)trans122.6-160.9-178.800000112.9V334 D335 R344 M361V334-G338 WeakPolarHBondContact CA-O 3.34Å; D335-G338 PolarHBondContact N-O 3.23Å; D335-G338 PolarHBondContact O-N 2.84Å; D335-G338 PolarHBondContact OD1-N 3.42Å; G338-R344 PolarHBondContact O-NH1 2.76Å; G338-M361 CarbonylContact C-O 3.6Å; G338-M361 VanDerWaalsContact CA-O 3.27Å; G338-M361 WeakPolarHBondContact CA-O 3.35Å
339L98.4Very high95.7Very high0 Ų052.6 Ų52.60%030%0.296CS..EExtended strand (participates in β ladder)trans-58.8137.2176.4-169.864.8000110.6L298 W332 V334 V341 R344 M361 I367L298-L339 HydrophobicContact CD1-CD1 4.49Å; W332-L339 HydrophobicContact CB-CD1 4.49Å; W332-L339 HydrophobicContact CE3-CD1 4.14Å; W332-L339 HydrophobicContact CE3-CD2 4.27Å; W332-L339 HydrophobicContact CE3-CG 4.48Å; W332-L339 HydrophobicContact CZ3-CD2 4.37Å; V334-L339 HydrophobicContact CG2-CD1 3.95Å; L339-V341 HydrophobicContact CB-CG1 4.19Å; L339-V341 HydrophobicContact CD2-CG1 3.69Å; L339-V341 HydrophobicContact CG-CG1 3.72Å; L339-V341 PolarHBondContact O-N 3.35Å; L339-R344 WeakPolarHBondContact O-CD 3.42Å; L339-R344 PolarHBondContact O-NH1 3.29Å; L339-M361 HydrophobicContact CB-CB 4.3Å; L339-M361 HydrophobicContact CD2-CB 4.48Å; L339-M361 HydrophobicContact CD2-SD 4.49Å; L339-M361 PolarHBondContact N-O 3.29Å; L339-I367 HydrophobicContact CB-CD1 4.02Å; L339-I367 HydrophobicContact CB-CG1 4.46Å; L339-I367 HydrophobicContact CD1-CG2 3.89Å
340I98.3Very high95.3Very high1 Ų147.7 Ų47.71%0.00528%0.275CS..  trans-77.8110.9172.2-56.4-51.5000108.1A302 L333 D335 R344 L347 K351 A355A302-I340 HydrophobicContact CB-CD1 4.42Å; A302-I340 HydrophobicContact CB-CG1 4.44Å; L333-I340 HydrophobicContact CB-CB 4.34Å; L333-I340 HydrophobicContact CB-CG1 3.7Å; L333-I340 WeakPolarHBondContact O-CG1 3.43Å; L333-I340 PolarHBondContact O-N 3.37Å; D335-I340 HydrophobicContact CB-CD1 4.33Å; D335-I340 WeakPolarHBondContact OD2-CD1 3.42Å; I340-R344 VanDerWaalsContact CD1-CZ 3.41Å; I340-L347 HydrophobicContact CD1-CD2 3.86Å; I340-L347 HydrophobicContact CG2-CD2 3.79Å; I340-K351 HydrophobicContact CD1-CD 4.03Å; I340-K351 HydrophobicContact CG2-CB 4.31Å; I340-A355 HydrophobicContact CG2-CB 3.95Å
341V98.2Very high95.1Very high2 Ų246.9 Ų46.91%0.01227%0.271CS..BIsolated β-bridgetrans-134.2156.5179.9-56.70000111L339 G343 R344 H356 H358 E360L339-V341 HydrophobicContact CB-CG1 4.19Å; L339-V341 HydrophobicContact CD2-CG1 3.69Å; L339-V341 HydrophobicContact CG-CG1 3.72Å; L339-V341 PolarHBondContact O-N 3.35Å; V341-G343 PolarHBondContact O-N 3.01Å; V341-R344 HydrophobicContact CG2-CB 3.96Å; V341-R344 VanDerWaalsContact O-CB 3.22Å; V341-R344 WeakPolarHBondContact O-CB 3.47Å; V341-R344 PolarHBondContact O-N 2.91Å; V341-H356 CarbonylContact C-O 3.54Å; V341-H356 WeakPolarHBondContact CA-O 3.33Å; V341-H356 WeakPolarHBondContact CB-O 3.49Å; V341-H358 HydrophobicContact CB-CB 4.47Å; V341-H358 HydrophobicContact CG1-CB 3.82Å; V341-E360 HydrophobicContact CG2-CB 4.5Å; V341-E360 HydrophobicContact CG2-CG 3.63Å
342K97.1Very high94.9Very high143 Ų14351.2 Ų51.262%0.62229%0.292SS*.THydrogen-bonded Turntrans-60.7129.4-176.4-171.7-178.3-175.8-172.60110.9R344 H356K342-R344 VanDerWaalsContact C-N 3.27Å; K342-R344 PolarHBondContact O-N 2.94Å; K342-H356 PolarHBondContact N-O 2.88Å
343G92.9Very high94.7Very high71 Ų7155.4 Ų55.473%0.73231%0.311SS*.THydrogen-bonded Turntrans82.2-1.9178.300000114.8V341V341-G343 PolarHBondContact O-N 3.01Å
344R94.5Very high94.7Very high14 Ų1456 Ų565%0.05331%0.313CS..  trans-63.1140.7173.3-168.3-171.879156.113.1110.5D335 G338 L339 I340 V341 K342 L347 E360D335-R344 VanDerWaalsContact CG-NH2 3.31Å; D335-R344 IonicContact OD1-CZ 3.48Å; D335-R344 IonicContact OD1-NH1 2.99Å; D335-R344 PolarHBondContact OD1-NH1 3.39Å; D335-R344 IonicContact OD1-NH2 3.11Å; D335-R344 PolarHBondContact OD1-NH2 2.72Å; D335-R344 VanDerWaalsContact OD1-NH2 3.11Å; D335-R344 IonicContact OD2-CZ 2.65Å; D335-R344 IonicContact OD2-NH2 2.64Å; D335-R344 PolarHBondContact OD2-NH2 3.27Å; G338-R344 PolarHBondContact O-NH1 2.76Å; L339-R344 WeakPolarHBondContact O-CD 3.42Å; L339-R344 PolarHBondContact O-NH1 3.29Å; I340-R344 VanDerWaalsContact CD1-CZ 3.41Å; V341-R344 HydrophobicContact CG2-CB 3.96Å; V341-R344 VanDerWaalsContact O-CB 3.22Å; V341-R344 WeakPolarHBondContact O-CB 3.47Å; V341-R344 PolarHBondContact O-N 2.91Å; K342-R344 VanDerWaalsContact C-N 3.27Å; K342-R344 PolarHBondContact O-N 2.94Å; R344-L347 HydrophobicContact CB-CD1 4.22Å; R344-L347 HydrophobicContact CB-CG 4.49Å; R344-L347 WeakPolarHBondContact O-CG 3.43Å; R344-E360 HydrophobicContact CG-CG 4.29Å; R344-E360 WeakPolarHBondContact CG-OE1 3.48Å
345A91.9Very high94.7Very high71 Ų7156.2 Ų56.259%0.58732%0.317SS*.SBendtrans-63.7158.3174.200000112.7
346S90.5Very high94.7Very high76 Ų7656.3 Ų56.353%0.53132%0.316SS..SBendtrans60.344.5172.4-52.80000115.6K337K337-S346 WeakPolarHBondContact CE-OG 3.44Å
347L91.5Very high94.9Very high30 Ų3059.1 Ų59.116%0.15732%0.317CS..  trans-95.7143.5171.2-65.4178.2000111.2I340 R344 K351 E352 A355I340-L347 HydrophobicContact CD1-CD2 3.86Å; I340-L347 HydrophobicContact CG2-CD2 3.79Å; R344-L347 HydrophobicContact CB-CD1 4.22Å; R344-L347 HydrophobicContact CB-CG 4.49Å; R344-L347 WeakPolarHBondContact O-CG 3.43Å; L347-K351 HydrophobicContact CD2-CB 4.07Å; L347-K351 HydrophobicContact CD2-CD 4.44Å; L347-E352 HydrophobicContact CB-CG 3.85Å; L347-E352 VanDerWaalsContact CB-OE1 3.28Å; L347-E352 WeakPolarHBondContact CB-OE1 3.26Å; L347-E352 VanDerWaalsContact CD1-CD 3.43Å; L347-E352 HydrophobicContact CD1-CG 4.34Å; L347-E352 WeakPolarHBondContact CD1-OE1 3.4Å; L347-E352 WeakPolarHBondContact CD1-OE2 3.36Å; L347-A355 HydrophobicContact CD1-CB 4.12Å
348T90.1Very high94.9Very high59 Ų5956.5 Ų56.536%0.36231%0.306SS..  trans-91162.3168.368.90000109.3E350 K351 E352T348-E350 PolarHBondContact O-N 2.91Å; T348-E350 VanDerWaalsContact O-N 3.14Å; T348-E350 PolarHBondContact OG1-OE2 3.07Å; T348-K351 PolarHBondContact O-N 2.91Å; T348-K351 WeakPolarHBondContact OG1-CG 3.21Å; T348-K351 PolarHBondContact OG1-N 3.3Å; T348-E352 WeakPolarHBondContact O-CG 3.47Å; T348-E352 PolarHBondContact O-N 2.93Å
349Q89.9Confident95Very high151 Ų15163.9 Ų63.971%0.70634%0.34SS*.Hα-helixtrans-55-34.8178.6-172-177.18.700112.6
350E90.5Very high94.9Very high45 Ų4569.9 Ų69.921%0.2137%0.368CS..Hα-helixtrans-70.6-37.8177.7-63.570.4-153.700112.3L307 T348L307-E350 HydrophobicContact CD1-CB 3.79Å; L307-E350 HydrophobicContact CD2-CB 4.2Å; T348-E350 PolarHBondContact O-N 2.91Å; T348-E350 VanDerWaalsContact O-N 3.14Å; T348-E350 PolarHBondContact OG1-OE2 3.07Å
351K94.3Very high94.9Very high30 Ų3071.8 Ų71.813%0.1338%0.378CS..Hα-helixtrans-73.2-37.5179.1-68.8177.7179-173.80112.2A302 L307 D335 I340 L347 T348 K353 F354 A355A302-K351 HydrophobicContact CB-CD 4.32Å; A302-K351 HydrophobicContact CB-CG 4.44Å; A302-K351 WeakPolarHBondContact O-CE 3.21Å; L307-K351 HydrophobicContact CD2-CG 4.39Å; D335-K351 IonicContact OD2-NZ 3.17Å; D335-K351 PolarHBondContact OD2-NZ 3.09Å; I340-K351 HydrophobicContact CD1-CD 4.03Å; I340-K351 HydrophobicContact CG2-CB 4.31Å; L347-K351 HydrophobicContact CD2-CB 4.07Å; L347-K351 HydrophobicContact CD2-CD 4.44Å; T348-K351 PolarHBondContact O-N 2.91Å; T348-K351 WeakPolarHBondContact OG1-CG 3.21Å; T348-K351 PolarHBondContact OG1-N 3.3Å; K351-K353 PolarHBondContact O-N 3.03Å; K351-K353 VanDerWaalsContact O-N 3.13Å; K351-F354 PolarHBondContact O-N 3.25Å; K351-A355 PolarHBondContact O-N 2.86Å
352E94.9Very high94.9Very high91 Ų9179.5 Ų79.543%0.42541%0.411SS..Hα-helixtrans-55.3-30.8178.4-73.7-71.6-174.600112.9L347 T348 F354 A355L347-E352 HydrophobicContact CB-CG 3.85Å; L347-E352 VanDerWaalsContact CB-OE1 3.28Å; L347-E352 WeakPolarHBondContact CB-OE1 3.26Å; L347-E352 VanDerWaalsContact CD1-CD 3.43Å; L347-E352 HydrophobicContact CD1-CG 4.34Å; L347-E352 WeakPolarHBondContact CD1-OE1 3.4Å; L347-E352 WeakPolarHBondContact CD1-OE2 3.36Å; T348-E352 WeakPolarHBondContact O-CG 3.47Å; T348-E352 PolarHBondContact O-N 2.93Å; E352-F354 PolarHBondContact O-N 3.45Å; E352-F354 VanDerWaalsContact O-N 3.13Å; E352-A355 WeakPolarHBondContact O-CB 3.44Å; E352-A355 PolarHBondContact O-N 3.19Å; E352-A355 VanDerWaalsContact O-N 3.12Å
353K95.4Very high94.9Very high123 Ų12377 Ų7754%0.53541%0.405SS..THydrogen-bonded Turntrans-61.9-22.1178.3-61.9173.7-167.7172.30113.5I328 K351I328-K353 WeakPolarHBondContact CG2-O 3.29Å; K351-K353 PolarHBondContact O-N 3.03Å; K351-K353 VanDerWaalsContact O-N 3.13Å
354F97.8Very high95.2Very high13 Ų1374.9 Ų74.96%0.05738%0.376CS..THydrogen-bonded Turntrans-114.811.6179.6-59.8-80.9000112.4L307 A310 V314 I328 I331 L333 K351 E352 H356L307-F354 HydrophobicContact CD2-CD2 4.28Å; L307-F354 HydrophobicContact CD2-CE2 4.29Å; A310-F354 HydrophobicContact CB-CE1 3.97Å; A310-F354 HydrophobicContact CB-CE2 4.04Å; A310-F354 HydrophobicContact CB-CZ 3.58Å; V314-F354 HydrophobicContact CG2-CE1 4.06Å; V314-F354 HydrophobicContact CG2-CZ 4.49Å; I328-F354 HydrophobicContact CG1-CE1 4.34Å; I328-F354 HydrophobicContact CG2-CD1 4.17Å; I331-F354 HydrophobicContact CB-CD1 4.08Å; I331-F354 HydrophobicContact CB-CE1 4.22Å; I331-F354 HydrophobicContact CD1-CE1 4.02Å; I331-F354 HydrophobicContact CG2-CD1 4.04Å; I331-F354 HydrophobicContact CG2-CE1 4.17Å; L333-F354 HydrophobicContact CD1-CB 3.22Å; L333-F354 HydrophobicContact CD1-CD1 4.12Å; L333-F354 HydrophobicContact CD1-CD2 3.74Å; L333-F354 HydrophobicContact CD1-CG 3.45Å; L333-F354 VanDerWaalsContact CD1-CG 3.45Å; K351-F354 PolarHBondContact O-N 3.25Å; E352-F354 PolarHBondContact O-N 3.45Å; E352-F354 VanDerWaalsContact O-N 3.13Å; F354-H356 PolarHBondContact O-CD2 2.95Å; F354-H356 PolarHBondContact O-N 3.5Å; F354-H356 VanDerWaalsContact O-N 3.16Å; F354-H356 PolarHBondContact O-NE2 3.39Å
355A97.6Very high95.3Very high16 Ų1677.4 Ų77.413%0.13239%0.389CS..  trans-8194.5-18000000110.3I340 L347 K351 E352I340-A355 HydrophobicContact CG2-CB 3.95Å; L347-A355 HydrophobicContact CD1-CB 4.12Å; K351-A355 PolarHBondContact O-N 2.86Å; E352-A355 WeakPolarHBondContact O-CB 3.44Å; E352-A355 PolarHBondContact O-N 3.19Å; E352-A355 VanDerWaalsContact O-N 3.12Å
356H96.9Very high95.7Very high23 Ų2375.7 Ų75.711%0.10637%0.374CS..BIsolated β-bridgetrans-79155.6177.9-52-53000111.5I328 I331 W332 V341 K342 F354 H358I328-H356 PolarHBondContact O-CE1 3.26Å; I328-H356 PolarHBondContact O-NE2 2.86Å; I331-H356 PolarHBondContact O-NE2 3.08Å; W332-H356 AromaticContact CD2-CD2 3.6Å; W332-H356 AromaticContact CE2-CD2 3.72Å; W332-H356 HydrophobicContact CE3-CB 4.49Å; W332-H356 AromaticContact CE3-CD2 3.5Å; W332-H356 HydrophobicContact CH2-CB 3.61Å; W332-H356 AromaticContact CH2-CD2 3.7Å; W332-H356 AromaticContact CH2-CG 3.91Å; W332-H356 HydrophobicContact CZ2-CB 4.33Å; W332-H356 AromaticContact CZ2-CD2 3.78Å; W332-H356 HydrophobicContact CZ3-CB 3.71Å; W332-H356 AromaticContact CZ3-CD2 3.56Å; V341-H356 CarbonylContact C-O 3.54Å; V341-H356 WeakPolarHBondContact CA-O 3.33Å; V341-H356 WeakPolarHBondContact CB-O 3.49Å; K342-H356 PolarHBondContact N-O 2.88Å; F354-H356 PolarHBondContact O-CD2 2.95Å; F354-H356 PolarHBondContact O-N 3.5Å; F354-H356 VanDerWaalsContact O-N 3.16Å; F354-H356 PolarHBondContact O-NE2 3.39Å; H356-H358 PolarHBondContact O-N 3.26Å; H356-H358 VanDerWaalsContact O-N 3.17Å
357E97.9Very high96Very high170 Ų17072 Ų7279%0.79435%0.349SS*.SBendtrans-70.1109.1168.2-174.7171.8-173.800109.1
358H98.2Very high96.4Very high55 Ų5570.6 Ų70.626%0.25534%0.342SS..  trans-163.6157.4-177.4-168.1-78.3000109.2W332 V341 H356W332-H358 HydrophobicContact CH2-CB 4.15Å; W332-H358 AromaticContact CH2-CD2 3.94Å; W332-H358 HydrophobicContact CZ3-CB 3.87Å; V341-H358 HydrophobicContact CB-CB 4.47Å; V341-H358 HydrophobicContact CG1-CB 3.82Å; H356-H358 PolarHBondContact O-N 3.26Å; H356-H358 VanDerWaalsContact O-N 3.17Å
359E97.5Very high96.8Very high158 Ų15871.9 Ų71.974%0.73834%0.343SS*.  trans-62.2143.6173-170.3173.9177.300111.5M361E359-M361 PolarHBondContact O-N 2.95Å
360E97.8Very high97.2Very high125 Ų12570.2 Ų70.258%0.58434%0.336SS*.  trans-65.8125.7173.1-72.2-168.9-166.800110.4V341 R344V341-E360 HydrophobicContact CG2-CB 4.5Å; V341-E360 HydrophobicContact CG2-CG 3.63Å; R344-E360 HydrophobicContact CG-CG 4.29Å; R344-E360 WeakPolarHBondContact CG-OE1 3.48Å
361M98.3Very high97.6Very high41 Ų4169.1 Ų69.120%0.20233%0.331CS..  trans-129.4141.5178.3-60.3-177.185.900110G338 L339 E359 A366 I367 E370G338-M361 CarbonylContact C-O 3.6Å; G338-M361 VanDerWaalsContact CA-O 3.27Å; G338-M361 WeakPolarHBondContact CA-O 3.35Å; L339-M361 HydrophobicContact CB-CB 4.3Å; L339-M361 HydrophobicContact CD2-CB 4.48Å; L339-M361 HydrophobicContact CD2-SD 4.49Å; L339-M361 PolarHBondContact N-O 3.29Å; E359-M361 PolarHBondContact O-N 2.95Å; M361-A366 HydrophobicContact CE-CB 3.83Å; M361-I367 HydrophobicContact CB-CD1 4Å; M361-I367 HydrophobicContact CB-CG1 3.49Å; M361-I367 VanDerWaalsContact CB-CG1 3.49Å; M361-I367 HydrophobicContact CE-CG1 4.44Å; M361-I367 HydrophobicContact CG-CG1 4.41Å; M361-I367 HydrophobicContact SD-CG1 4.07Å; M361-E370 HydrophobicContact CE-CB 3.97Å; M361-E370 HydrophobicContact CE-CG 4.43Å; M361-E370 HydrophobicContact SD-CB 4.01Å; M361-E370 HydrophobicContact SD-CG 4.07Å
362K96.7Very high97.8Very high164 Ų16473.6 Ų73.671%0.71335%0.351SS*.  trans-113.1-35.9-179.6-169.7178.1179.2-178.20114
363N97.9Very high98Very high91 Ų9169.3 Ų69.349%0.48733%0.33SS..  trans-79.4122.8-176.7177.6-74.8000110.4E365 A366 I367N363-E365 PolarHBondContact O-N 3.02Å; N363-E365 WeakPolarHBondContact OD1-CA 3.36Å; N363-E365 VanDerWaalsContact OD1-CB 3.31Å; N363-E365 WeakPolarHBondContact OD1-CB 3.29Å; N363-E365 PolarHBondContact OD1-N 3.21Å; N363-A366 HydrophobicContact CB-CB 4.19Å; N363-A366 PolarHBondContact O-N 3.03Å; N363-A366 PolarHBondContact OD1-N 3.22Å; N363-I367 VanDerWaalsContact O-CG1 3.27Å; N363-I367 WeakPolarHBondContact O-CG1 3.27Å; N363-I367 PolarHBondContact O-N 3.04Å
364L98.3Very high98.2Very high26 Ų2664.7 Ų64.714%0.13631%0.312CS..Hα-helixtrans-64.9-36.4-175.4-17564000113.1Q300 V334 I367 V368 F386 I390Q300-L364 HydrophobicContact CB-CD2 4.3Å; Q300-L364 HydrophobicContact CG-CD2 3.97Å; V334-L364 HydrophobicContact CG2-CD1 4.24Å; L364-I367 PolarHBondContact O-N 2.93Å; L364-V368 VanDerWaalsContact O-CG2 3.29Å; L364-V368 WeakPolarHBondContact O-CG2 3.4Å; L364-V368 PolarHBondContact O-N 3.13Å; L364-F386 HydrophobicContact CD2-CD1 4.36Å; L364-F386 HydrophobicContact CD2-CE1 4.36Å; L364-I390 HydrophobicContact CB-CD1 4.25Å; L364-I390 HydrophobicContact CD2-CD1 3.74Å; L364-I390 HydrophobicContact CG-CD1 3.73Å
365E98.4Very high98.2Very high67 Ų6764 Ų6431%0.31331%0.31SS..Hα-helixtrans-60.9-47.9175.6-75.1169.5-174.300111N363 I367 V368 Q369 S387 Q389 I390N363-E365 PolarHBondContact O-N 3.02Å; N363-E365 WeakPolarHBondContact OD1-CA 3.36Å; N363-E365 VanDerWaalsContact OD1-CB 3.31Å; N363-E365 WeakPolarHBondContact OD1-CB 3.29Å; N363-E365 PolarHBondContact OD1-N 3.21Å; E365-I367 VanDerWaalsContact C-N 3.34Å; E365-I367 PolarHBondContact O-N 2.68Å; E365-V368 PolarHBondContact O-N 3.35Å; E365-Q369 WeakPolarHBondContact O-CG 3.29Å; E365-Q369 PolarHBondContact O-N 3.48Å; E365-S387 WeakPolarHBondContact OE1-CB 3.43Å; E365-S387 PolarHBondContact OE1-OG 3.13Å; E365-Q389 HydrophobicContact CG-CB 4.45Å; E365-I390 HydrophobicContact CB-CG1 4.3Å; E365-I390 HydrophobicContact CG-CD1 3.91Å; E365-I390 HydrophobicContact CG-CG1 3.42Å; E365-I390 VanDerWaalsContact CG-CG1 3.42Å
366A98.4Very high98.3Very high35 Ų3563.3 Ų63.329%0.28930%0.303SS..Hα-helixtrans-62-40.9176.500000112M361 N363 V368 Q369 E370M361-A366 HydrophobicContact CE-CB 3.83Å; N363-A366 HydrophobicContact CB-CB 4.19Å; N363-A366 PolarHBondContact O-N 3.03Å; N363-A366 PolarHBondContact OD1-N 3.22Å; A366-V368 VanDerWaalsContact C-N 3.35Å; A366-V368 PolarHBondContact O-N 2.89Å; A366-Q369 PolarHBondContact O-N 2.93Å; A366-E370 WeakPolarHBondContact O-CB 3.47Å; A366-E370 PolarHBondContact O-N 3.11Å
367I98.8Very high98.4Very high0 Ų062.2 Ų62.20%030%0.298CS..Hα-helixtrans-61.7-43.3175.7-67.5163.8000110.8L298 V334 L339 M361 N363 L364 E365 Q369 E370 I371L298-I367 HydrophobicContact CD1-CG2 3.89Å; L298-I367 HydrophobicContact CD2-CG2 3.84Å; V334-I367 HydrophobicContact CG1-CD1 4.18Å; V334-I367 HydrophobicContact CG2-CD1 3.96Å; V334-I367 HydrophobicContact CG2-CG2 4.18Å; L339-I367 HydrophobicContact CB-CD1 4.02Å; L339-I367 HydrophobicContact CB-CG1 4.46Å; L339-I367 HydrophobicContact CD1-CG2 3.89Å; M361-I367 HydrophobicContact CB-CD1 4Å; M361-I367 HydrophobicContact CB-CG1 3.49Å; M361-I367 VanDerWaalsContact CB-CG1 3.49Å; M361-I367 HydrophobicContact CE-CG1 4.44Å; M361-I367 HydrophobicContact CG-CG1 4.41Å; M361-I367 HydrophobicContact SD-CG1 4.07Å; N363-I367 VanDerWaalsContact O-CG1 3.27Å; N363-I367 WeakPolarHBondContact O-CG1 3.27Å; N363-I367 PolarHBondContact O-N 3.04Å; L364-I367 PolarHBondContact O-N 2.93Å; E365-I367 VanDerWaalsContact C-N 3.34Å; E365-I367 PolarHBondContact O-N 2.68Å; I367-Q369 VanDerWaalsContact C-N 3.31Å; I367-Q369 PolarHBondContact O-N 3.1Å; I367-E370 PolarHBondContact O-N 3.44Å; I367-I371 HydrophobicContact CG2-CG1 3.96Å; I367-I371 WeakPolarHBondContact O-CB 3.45Å; I367-I371 VanDerWaalsContact O-CG1 3.29Å; I367-I371 WeakPolarHBondContact O-CG1 3.22Å; I367-I371 PolarHBondContact O-N 3.2Å
368V98.8Very high98.4Very high0 Ų054.1 Ų54.10%026%0.261CS..Hα-helixtrans-61.6-41.4177.6167.40000111L298 L364 E365 A366 K372 P373 L376 I390 D393 M394 F397L298-V368 HydrophobicContact CD2-CG2 3.69Å; L364-V368 VanDerWaalsContact O-CG2 3.29Å; L364-V368 WeakPolarHBondContact O-CG2 3.4Å; L364-V368 PolarHBondContact O-N 3.13Å; E365-V368 PolarHBondContact O-N 3.35Å; A366-V368 VanDerWaalsContact C-N 3.35Å; A366-V368 PolarHBondContact O-N 2.89Å; V368-K372 WeakPolarHBondContact O-CA 3.42Å; V368-K372 PolarHBondContact O-N 3.06Å; V368-P373 WeakPolarHBondContact O-CD 3.32Å; V368-L376 HydrophobicContact CG2-CD1 4.38Å; V368-I390 HydrophobicContact CG1-CG2 4.43Å; V368-I390 HydrophobicContact CG2-CD1 4.45Å; V368-I390 HydrophobicContact CG2-CG2 4.13Å; V368-D393 HydrophobicContact CG1-CB 4.27Å; V368-M394 HydrophobicContact CG1-CG 4.27Å; V368-M394 HydrophobicContact CG1-SD 4.07Å; V368-F397 HydrophobicContact CG1-CE2 4.14Å; V368-F397 WeakPolarHBondContact O-CE2 3.39Å
369Q98.7Very high98.3Very high85 Ų8552.7 Ų52.740%0.39726%0.256SS..Hα-helixtrans-68.6-33.8178.8-70.2171.7-0.300113.5E365 A366 I367 K372 D393 F397E365-Q369 WeakPolarHBondContact O-CG 3.29Å; E365-Q369 PolarHBondContact O-N 3.48Å; A366-Q369 PolarHBondContact O-N 2.93Å; I367-Q369 VanDerWaalsContact C-N 3.31Å; I367-Q369 PolarHBondContact O-N 3.1Å; Q369-K372 WeakPolarHBondContact O-CE 3.37Å; Q369-K372 WeakPolarHBondContact O-CG 3.25Å; Q369-D393 WeakPolarHBondContact CG-OD2 3.48Å; Q369-D393 PolarHBondContact NE2-OD2 2.95Å; Q369-F397 HydrophobicContact CG-CZ 4.3Å
370E98.6Very high98.1Very high116 Ų11647 Ų4754%0.54224%0.235SC..Hα-helixtrans-76.9-53.3178.1-173.958.4-149.700111.4M361 A366 I367 K372M361-E370 HydrophobicContact CE-CB 3.97Å; M361-E370 HydrophobicContact CE-CG 4.43Å; M361-E370 HydrophobicContact SD-CB 4.01Å; M361-E370 HydrophobicContact SD-CG 4.07Å; A366-E370 WeakPolarHBondContact O-CB 3.47Å; A366-E370 PolarHBondContact O-N 3.11Å; I367-E370 PolarHBondContact O-N 3.44Å; E370-K372 PolarHBondContact O-N 3.07Å
371I98.6Very high97.9Very high22 Ų2242.8 Ų42.811%0.11322%0.222CC..Hα-helixtrans-72.6-29.7-175.6-58.9-54.6000112T296 W332 I367 P373T296-I371 HydrophobicContact CG2-CG2 3.96Å; W332-I371 HydrophobicContact CB-CG2 4.47Å; W332-I371 HydrophobicContact CD2-CD1 3.71Å; W332-I371 HydrophobicContact CD2-CG1 4.35Å; W332-I371 HydrophobicContact CD2-CG2 4.32Å; W332-I371 HydrophobicContact CE3-CD1 3.71Å; W332-I371 HydrophobicContact CG-CD1 4.33Å; W332-I371 HydrophobicContact CG-CG1 4.49Å; W332-I371 HydrophobicContact CG-CG2 3.89Å; W332-I371 HydrophobicContact CH2-CD1 4.09Å; W332-I371 HydrophobicContact CZ2-CD1 4.1Å; W332-I371 HydrophobicContact CZ3-CD1 3.9Å; I367-I371 HydrophobicContact CG2-CG1 3.96Å; I367-I371 WeakPolarHBondContact O-CB 3.45Å; I367-I371 VanDerWaalsContact O-CG1 3.29Å; I367-I371 WeakPolarHBondContact O-CG1 3.22Å; I367-I371 PolarHBondContact O-N 3.2Å; I371-P373 HydrophobicContact CG2-CB 4.36Å
372K98.8Very high97.7Very high125 Ų12545.2 Ų45.254%0.54324%0.235SC..  trans46.156-175.7-59.2179.5-178.5165.10112.5V368 Q369 E370 F397V368-K372 WeakPolarHBondContact O-CA 3.42Å; V368-K372 PolarHBondContact O-N 3.06Å; Q369-K372 WeakPolarHBondContact O-CE 3.37Å; Q369-K372 WeakPolarHBondContact O-CG 3.25Å; E370-K372 PolarHBondContact O-N 3.07Å; K372-F397 HydrophobicContact CB-CD2 4Å; K372-F397 HydrophobicContact CB-CE2 4.43Å; K372-F397 HydrophobicContact CB-CG 4.24Å; K372-F397 HydrophobicContact CD-CD1 4.49Å; K372-F397 HydrophobicContact CG-CD1 4.42Å; K372-F397 HydrophobicContact CG-CD2 4.01Å; K372-F397 HydrophobicContact CG-CE1 4.44Å; K372-F397 HydrophobicContact CG-CE2 4.01Å; K372-F397 HydrophobicContact CG-CG 4.23Å; K372-F397 HydrophobicContact CG-CZ 4.25Å
373P98.8Very high97.7Very high0 Ų039.4 Ų39.40%022%0.222CC..  trans-67.7154.6-17531.5-35.9000111.5T296 L298 V368 I371 M394 N398T296-P373 HydrophobicContact CG2-CB 4.47Å; T296-P373 CarbonylContact O-C 3.09Å; T296-P373 WeakPolarHBondContact O-CA 3.39Å; T296-P373 WeakPolarHBondContact O-CB 3.49Å; L298-P373 HydrophobicContact CB-CB 3.66Å; L298-P373 HydrophobicContact CB-CG 3.65Å; L298-P373 HydrophobicContact CD2-CG 3.94Å; L298-P373 HydrophobicContact CG-CG 4.46Å; V368-P373 WeakPolarHBondContact O-CD 3.32Å; I371-P373 HydrophobicContact CG2-CB 4.36Å; P373-M394 HydrophobicContact CG-CE 4.35Å; P373-M394 HydrophobicContact CG-SD 3.76Å; P373-M394 WeakPolarHBondContact O-CE 3.44Å; P373-N398 PolarHBondContact O-ND2 3.22Å
374T98.8Very high97.6Very high26 Ų2637.2 Ų37.216%0.1622%0.22CC..SBendtrans-87.2-28.7172.163.20000111.9Q295 T296 N398 I402Q295-T374 WeakPolarHBondContact CA-OG1 3.38Å; Q295-T374 WeakPolarHBondContact CB-OG1 3.4Å; Q295-T374 VanDerWaalsContact OE1-CB 3.25Å; Q295-T374 PolarHBondContact OE1-OG1 3.14Å; T296-T374 PolarHBondContact N-OG1 2.81Å; T296-T374 PolarHBondContact O-N 3.39Å; T296-T374 PolarHBondContact O-OG1 3.15Å; T374-N398 WeakPolarHBondContact CA-OD1 3.39Å; T374-N398 WeakPolarHBondContact CG2-OD1 3.16Å; T374-I402 PolarHBondContact O-N 3.05Å; T374-I402 VanDerWaalsContact O-N 3.08Å
375A98.9Very high97.6Very high0 Ų037 Ų370%022%0.222CC..EExtended strand (participates in β ladder)trans-126.4130.1174.800000111.4L281 T296 I297 L298 I402L281-A375 HydrophobicContact CD2-CB 4.35Å; T296-A375 PolarHBondContact O-N 3.28Å; I297-A375 WeakPolarHBondContact CA-O 3.4Å; I297-A375 HydrophobicContact CG1-CB 4.26Å; I297-A375 HydrophobicContact CG2-CB 4.27Å; L298-A375 PolarHBondContact N-O 3.11Å; A375-I402 CarbonylContact C-O 3.53Å; A375-I402 WeakPolarHBondContact CA-O 3.35Å; A375-I402 HydrophobicContact CB-CB 3.82Å; A375-I402 HydrophobicContact CB-CD1 4.38Å; A375-I402 HydrophobicContact CB-CG2 4.1Å
376L98.9Very high97.6Very high0 Ų033.8 Ų33.80%021%0.207CC..EExtended strand (participates in β ladder)trans-115120.3175.2-179.365.9000109.4L298 V368 F386 I390 M394 I402 I403 F404L298-L376 HydrophobicContact CB-CD1 4.11Å; L298-L376 HydrophobicContact CD2-CD1 3.91Å; L298-L376 HydrophobicContact CG-CD1 4Å; L298-L376 WeakPolarHBondContact O-CA 3.18Å; V368-L376 HydrophobicContact CG2-CD1 4.38Å; L376-F386 HydrophobicContact CD1-CE1 4.09Å; L376-F386 HydrophobicContact CD1-CZ 4.18Å; L376-F386 HydrophobicContact CD2-CD1 3.72Å; L376-F386 HydrophobicContact CD2-CD2 4.06Å; L376-F386 HydrophobicContact CD2-CE1 3.65Å; L376-F386 HydrophobicContact CD2-CE2 3.98Å; L376-F386 HydrophobicContact CD2-CG 3.95Å; L376-F386 HydrophobicContact CD2-CZ 3.79Å; L376-F386 HydrophobicContact CG-CD1 4.34Å; L376-F386 HydrophobicContact CG-CE1 3.75Å; L376-F386 HydrophobicContact CG-CE2 3.94Å; L376-F386 HydrophobicContact CG-CZ 3.52Å; L376-I390 HydrophobicContact CD2-CG2 3.46Å; L376-I390 VanDerWaalsContact CD2-CG2 3.46Å; L376-M394 HydrophobicContact CB-CE 3.74Å; L376-M394 HydrophobicContact CB-SD 4.1Å; L376-M394 HydrophobicContact CD2-CG 4.21Å; L376-I402 PolarHBondContact N-O 3.04Å; L376-I403 WeakPolarHBondContact O-CA 3.5Å; L376-F404 PolarHBondContact O-N 3.03Å
377I98.8Very high97.6Very high0 Ų033.3 Ų33.30%020%0.202CC..EExtended strand (participates in β ladder)trans-123119.5-173.7-53.9178.9000110.1L281 I297 L298 F299 Q300 I309 V379 F404 L406L281-I377 HydrophobicContact CD1-CD1 4.31Å; I297-I377 HydrophobicContact CG2-CD1 3.72Å; I297-I377 HydrophobicContact CG2-CG1 4.25Å; L298-I377 PolarHBondContact O-N 2.81Å; F299-I377 CarbonylContact C-O 3.59Å; F299-I377 VanDerWaalsContact CA-O 3.29Å; F299-I377 WeakPolarHBondContact CA-O 3.24Å; F299-I377 HydrophobicContact CD1-CB 3.73Å; F299-I377 HydrophobicContact CD1-CG2 3.84Å; F299-I377 HydrophobicContact CE1-CB 3.74Å; F299-I377 HydrophobicContact CE1-CD1 3.72Å; F299-I377 HydrophobicContact CE1-CG1 4.28Å; F299-I377 HydrophobicContact CE1-CG2 3.66Å; F299-I377 HydrophobicContact CG-CB 4.48Å; F299-I377 HydrophobicContact CZ-CB 4.47Å; F299-I377 HydrophobicContact CZ-CD1 3.72Å; Q300-I377 PolarHBondContact N-O 3.26Å; I309-I377 HydrophobicContact CD1-CG2 4.45Å; I377-V379 HydrophobicContact CG2-CG1 4.44Å; I377-F404 CarbonylContact C-O 3.6Å; I377-F404 WeakPolarHBondContact CA-O 3.47Å; I377-F404 HydrophobicContact CB-CB 4.39Å; I377-F404 HydrophobicContact CD1-CD2 4.32Å; I377-F404 HydrophobicContact CG1-CB 4.18Å; I377-F404 HydrophobicContact CG1-CD2 4.25Å; I377-F404 HydrophobicContact CG1-CG 4.47Å; I377-F404 HydrophobicContact CG2-CB 4.11Å; I377-L406 HydrophobicContact CG2-CD1 3.88Å; I377-L406 HydrophobicContact CG2-CG 4.46Å
378G98.3Very high97.6Very high0 Ų038.1 Ų38.10%022%0.224CC..EExtended strand (participates in β ladder)trans-104.3125.9-179.400000112F404 L406 E414G378-F404 PolarHBondContact N-O 2.75Å; G378-L406 WeakPolarHBondContact O-CA 3.36Å; G378-L406 VanDerWaalsContact O-CB 3.31Å; G378-L406 WeakPolarHBondContact O-CB 3.26Å; G378-L406 PolarHBondContact O-N 3.02Å; G378-E414 VanDerWaalsContact C-CD 3.46Å; G378-E414 VanDerWaalsContact CA-CD 3.46Å; G378-E414 VanDerWaalsContact CA-OE1 3.31Å; G378-E414 WeakPolarHBondContact CA-OE1 3.29Å
379V96.2Very high97.6Very high26 Ų2641.7 Ų41.716%0.15824%0.241CC..  trans-146.128.3-179.9-71.60000111.1Q300 A305 A306 I309 I377 L406 E414Q300-V379 PolarHBondContact O-N 3.41Å; A305-V379 HydrophobicContact CB-CB 4.05Å; A305-V379 HydrophobicContact CB-CG1 3.98Å; A305-V379 HydrophobicContact CB-CG2 4.42Å; A306-V379 HydrophobicContact CB-CG2 3.64Å; I309-V379 HydrophobicContact CD1-CG1 4.17Å; I377-V379 HydrophobicContact CG2-CG1 4.44Å; V379-L406 HydrophobicContact CG1-CB 3.86Å; V379-L406 HydrophobicContact CG1-CD1 4.12Å; V379-L406 HydrophobicContact CG1-CG 4.47Å; V379-E414 PolarHBondContact N-OE1 3.35Å
380A94.2Very high97.6Very high37 Ų3737.7 Ų37.731%0.30622%0.223SC..SBendtrans-102.7-4-171.900000114.5Q300 I382 S407 E414Q300-A380 HydrophobicContact CG-CB 4.05Å; Q300-A380 PolarHBondContact O-N 3.08Å; A380-I382 VanDerWaalsContact C-N 3.28Å; A380-I382 HydrophobicContact CB-CD1 4.17Å; A380-I382 HydrophobicContact CB-CG1 3.96Å; A380-I382 PolarHBondContact O-N 3.19Å; A380-S407 PolarHBondContact N-OG 3.27Å; A380-E414 PolarHBondContact N-OE1 2.88Å
381A93Very high97.6Very high37 Ų3732.2 Ų32.231%0.30620%0.197SC..  trans55.738.8-171.500000113.8S407 K412A381-S407 WeakPolarHBondContact CA-OG 3.12Å; A381-S407 PolarHBondContact N-OG 3.33Å; A381-K412 HydrophobicContact CB-CB 4.27Å; A381-K412 HydrophobicContact CB-CG 4.49Å
382I94.3Very high97.6Very high93 Ų9335.6 Ų35.648%0.47721%0.211SC..  trans-110.896.3176.8-52.2-174.9000108.6A380 G384 A385A380-I382 VanDerWaalsContact C-N 3.28Å; A380-I382 HydrophobicContact CB-CD1 4.17Å; A380-I382 HydrophobicContact CB-CG1 3.96Å; A380-I382 PolarHBondContact O-N 3.19Å; I382-G384 PolarHBondContact O-N 3.23Å; I382-A385 HydrophobicContact CB-CB 4.14Å; I382-A385 HydrophobicContact CG2-CB 4.01Å; I382-A385 VanDerWaalsContact O-CB 3.28Å; I382-A385 WeakPolarHBondContact O-CB 3.47Å; I382-A385 PolarHBondContact O-N 3.26Å
383G95.8Very high97.6Very high42 Ų4230.6 Ų30.643%0.43319%0.19SC..THydrogen-bonded Turntrans-58.9131.3-179.300000112.3A385 A413G383-A385 VanDerWaalsContact C-N 3.29Å; G383-A385 PolarHBondContact O-N 3.2Å; G383-A413 WeakPolarHBondContact CA-O 3.47Å
384G96.9Very high97.6Very high44 Ų4430.6 Ų30.645%0.45419%0.19SC..THydrogen-bonded Turntrans74.312.1178.500000115.3I382 F386 A413 E414I382-G384 PolarHBondContact O-N 3.23Å; G384-F386 PolarHBondContact O-N 2.93Å; G384-A413 PolarHBondContact N-O 2.99Å; G384-A413 VanDerWaalsContact N-O 3.11Å; G384-E414 CarbonylContact C-O 3.5Å; G384-E414 WeakPolarHBondContact CA-O 3.38Å; G384-E414 PolarHBondContact N-O 2.98Å
385A97.7Very high97.6Very high21 Ų2129.9 Ų29.917%0.17419%0.187CC..  trans-62.1-29.3179.600000114.1Q300 I382 G383 S387 I390 E414Q300-A385 VanDerWaalsContact CD-CB 3.5Å; I382-A385 HydrophobicContact CB-CB 4.14Å; I382-A385 HydrophobicContact CG2-CB 4.01Å; I382-A385 VanDerWaalsContact O-CB 3.28Å; I382-A385 WeakPolarHBondContact O-CB 3.47Å; I382-A385 PolarHBondContact O-N 3.26Å; G383-A385 VanDerWaalsContact C-N 3.29Å; G383-A385 PolarHBondContact O-N 3.2Å; A385-S387 VanDerWaalsContact C-N 3.3Å; A385-S387 PolarHBondContact O-N 3.46Å; A385-S387 VanDerWaalsContact O-N 3.08Å; A385-I390 WeakPolarHBondContact O-CD1 3.32Å; A385-E414 HydrophobicContact CB-CB 4.47Å; A385-E414 HydrophobicContact CB-CG 4.31Å; A385-E414 PolarHBondContact N-O 2.84Å; A385-E414 VanDerWaalsContact N-O 3.08Å
386F98.6Very high97.6Very high0 Ų033.6 Ų33.60%022%0.217CC..SBendtrans-85.779.4173.6-62.7-8.3000108.7Q300 L364 L376 G384 L391 I403 E414 C415 Q419Q300-F386 HydrophobicContact CB-CE1 4.08Å; L364-F386 HydrophobicContact CD2-CD1 4.36Å; L364-F386 HydrophobicContact CD2-CE1 4.36Å; L376-F386 HydrophobicContact CD1-CE1 4.09Å; L376-F386 HydrophobicContact CD1-CZ 4.18Å; L376-F386 HydrophobicContact CD2-CD1 3.72Å; L376-F386 HydrophobicContact CD2-CD2 4.06Å; L376-F386 HydrophobicContact CD2-CE1 3.65Å; L376-F386 HydrophobicContact CD2-CE2 3.98Å; L376-F386 HydrophobicContact CD2-CG 3.95Å; L376-F386 HydrophobicContact CD2-CZ 3.79Å; L376-F386 HydrophobicContact CG-CD1 4.34Å; L376-F386 HydrophobicContact CG-CE1 3.75Å; L376-F386 HydrophobicContact CG-CE2 3.94Å; L376-F386 HydrophobicContact CG-CZ 3.52Å; G384-F386 PolarHBondContact O-N 2.93Å; F386-L391 HydrophobicContact CB-CD2 4.19Å; F386-I403 HydrophobicContact CD2-CG2 3.85Å; F386-I403 HydrophobicContact CE2-CG2 4.12Å; F386-E414 HydrophobicContact CB-CB 4.25Å; F386-E414 HydrophobicContact CD1-CB 3.85Å; F386-E414 HydrophobicContact CD1-CG 4.28Å; F386-E414 HydrophobicContact CD2-CB 3.52Å; F386-E414 HydrophobicContact CD2-CG 4.42Å; F386-E414 HydrophobicContact CE1-CB 3.97Å; F386-E414 HydrophobicContact CE1-CG 3.96Å; F386-E414 HydrophobicContact CE2-CB 3.67Å; F386-E414 HydrophobicContact CE2-CG 4.13Å; F386-E414 HydrophobicContact CG-CB 3.61Å; F386-E414 HydrophobicContact CG-CG 4.49Å; F386-E414 HydrophobicContact CZ-CB 3.88Å; F386-E414 HydrophobicContact CZ-CG 3.88Å; F386-E414 PolarHBondContact N-O 3.26Å; F386-C415 HydrophobicContact CB-CB 3.96Å; F386-Q419 PolarHBondContact O-NE2 3.24Å
387S98.6Very high97.6Very high26 Ų2637 Ų3718%0.18223%0.232CC..  trans-60.9166.8-178.9770000112.2E365 A385 Q389 I390 L391E365-S387 WeakPolarHBondContact OE1-CB 3.43Å; E365-S387 PolarHBondContact OE1-OG 3.13Å; A385-S387 VanDerWaalsContact C-N 3.3Å; A385-S387 PolarHBondContact O-N 3.46Å; A385-S387 VanDerWaalsContact O-N 3.08Å; S387-Q389 PolarHBondContact O-N 2.9Å; S387-Q389 PolarHBondContact OG-N 3.2Å; S387-I390 PolarHBondContact O-N 3.05Å; S387-I390 PolarHBondContact OG-N 2.77Å; S387-L391 WeakPolarHBondContact O-CG 3.3Å; S387-L391 PolarHBondContact O-N 3.04Å
388E98.6Very high97.6Very high100 Ų10038.1 Ų38.147%0.46724%0.238SC..Hα-helixtrans-55.1-36.5173.4177.2173.8160.100112.6L391 K392 I423E388-L391 PolarHBondContact O-N 2.94Å; E388-K392 HydrophobicContact CG-CD 4.25Å; E388-K392 WeakPolarHBondContact O-CB 3.12Å; E388-K392 WeakPolarHBondContact O-CG 3.38Å; E388-K392 PolarHBondContact O-N 3.04Å; E388-K392 WeakPolarHBondContact OE1-CE 3.37Å; E388-K392 IonicContact OE1-NZ 2.77Å; E388-K392 PolarHBondContact OE1-NZ 2.66Å; E388-I423 HydrophobicContact CB-CD1 3.83Å; E388-I423 HydrophobicContact CG-CD1 3.74Å; E388-I423 HydrophobicContact CG-CG1 4.05Å; E388-I423 HydrophobicContact CG-CG2 4.23Å
389Q98.7Very high97.6Very high76 Ų7646 Ų4636%0.35528%0.275SS..Hα-helixtrans-66.6-47.4178.8-171.95647.600111.4E365 S387 L391 K392 D393E365-Q389 HydrophobicContact CG-CB 4.45Å; S387-Q389 PolarHBondContact O-N 2.9Å; S387-Q389 PolarHBondContact OG-N 3.2Å; Q389-L391 VanDerWaalsContact C-N 3.32Å; Q389-L391 PolarHBondContact O-N 3.14Å; Q389-K392 PolarHBondContact O-N 3Å; Q389-D393 VanDerWaalsContact NE2-CG 3.31Å; Q389-D393 PolarHBondContact NE2-OD1 3.34Å; Q389-D393 PolarHBondContact NE2-OD2 3.25Å; Q389-D393 VanDerWaalsContact NE2-OD2 3.14Å; Q389-D393 WeakPolarHBondContact O-CB 3.15Å; Q389-D393 VanDerWaalsContact O-CG 3.24Å; Q389-D393 PolarHBondContact O-N 2.95Å
390I98.8Very high97.7Very high1 Ų149 Ų491%0.00528%0.283CS..Hα-helixtrans-57-46.3176-67.3-172.5000111.3L364 E365 V368 L376 A385 S387 K392 D393 M394L364-I390 HydrophobicContact CB-CD1 4.25Å; L364-I390 HydrophobicContact CD2-CD1 3.74Å; L364-I390 HydrophobicContact CG-CD1 3.73Å; E365-I390 HydrophobicContact CB-CG1 4.3Å; E365-I390 HydrophobicContact CG-CD1 3.91Å; E365-I390 HydrophobicContact CG-CG1 3.42Å; E365-I390 VanDerWaalsContact CG-CG1 3.42Å; V368-I390 HydrophobicContact CG1-CG2 4.43Å; V368-I390 HydrophobicContact CG2-CD1 4.45Å; V368-I390 HydrophobicContact CG2-CG2 4.13Å; L376-I390 HydrophobicContact CD2-CG2 3.46Å; L376-I390 VanDerWaalsContact CD2-CG2 3.46Å; A385-I390 WeakPolarHBondContact O-CD1 3.32Å; S387-I390 PolarHBondContact O-N 3.05Å; S387-I390 PolarHBondContact OG-N 2.77Å; I390-K392 PolarHBondContact O-N 3.36Å; I390-D393 PolarHBondContact O-N 3.08Å; I390-M394 HydrophobicContact CG2-CG 4.31Å; I390-M394 WeakPolarHBondContact O-CB 3.32Å; I390-M394 VanDerWaalsContact O-CG 3.32Å; I390-M394 WeakPolarHBondContact O-CG 3.28Å; I390-M394 PolarHBondContact O-N 3.44Å
391L98.9Very high97.9Very high0 Ų047.2 Ų47.20%027%0.269CS..Hα-helixtrans-65.4-38.9-178.4-64172.9000111.7F386 S387 E388 Q389 A395 I403 C415 Q419 I423 T424F386-L391 HydrophobicContact CB-CD2 4.19Å; S387-L391 WeakPolarHBondContact O-CG 3.3Å; S387-L391 PolarHBondContact O-N 3.04Å; E388-L391 PolarHBondContact O-N 2.94Å; Q389-L391 VanDerWaalsContact C-N 3.32Å; Q389-L391 PolarHBondContact O-N 3.14Å; L391-A395 VanDerWaalsContact O-CB 3.31Å; L391-A395 WeakPolarHBondContact O-CB 3.34Å; L391-A395 PolarHBondContact O-N 2.9Å; L391-A395 VanDerWaalsContact O-N 3.12Å; L391-I403 HydrophobicContact CD2-CD1 3.67Å; L391-I403 HydrophobicContact CD2-CG2 4.2Å; L391-C415 HydrophobicContact CD1-CB 4.42Å; L391-Q419 HydrophobicContact CD1-CG 3.76Å; L391-I423 HydrophobicContact CB-CB 4.21Å; L391-I423 HydrophobicContact CB-CG2 3.65Å; L391-I423 HydrophobicContact CD1-CB 4.46Å; L391-I423 HydrophobicContact CD1-CD1 3.8Å; L391-T424 HydrophobicContact CB-CG2 4.37Å
392K98.8Very high98.2Very high94 Ų9445.5 Ų45.541%0.40926%0.255SS..Hα-helixtrans-62.6-45.9172.6-77177.4-177.2166.70111.6E388 Q389 I390 A395 A396 I423E388-K392 HydrophobicContact CG-CD 4.25Å; E388-K392 WeakPolarHBondContact O-CB 3.12Å; E388-K392 WeakPolarHBondContact O-CG 3.38Å; E388-K392 PolarHBondContact O-N 3.04Å; E388-K392 WeakPolarHBondContact OE1-CE 3.37Å; E388-K392 IonicContact OE1-NZ 2.77Å; E388-K392 PolarHBondContact OE1-NZ 2.66Å; Q389-K392 PolarHBondContact O-N 3Å; I390-K392 PolarHBondContact O-N 3.36Å; K392-A395 CarbonylContact O-C 3.58Å; K392-A395 PolarHBondContact O-N 3.39Å; K392-A396 WeakPolarHBondContact O-CB 3.18Å; K392-A396 PolarHBondContact O-N 3.48Å; K392-I423 HydrophobicContact CG-CG2 3.61Å
393D98.8Very high98.4Very high20 Ų2041.1 Ų41.111%0.10723%0.232CC..Hα-helixtrans-63.8-47.9-178.6-70.7-19.4000110.8V368 Q369 Q389 I390 A395 A396 F397V368-D393 HydrophobicContact CG1-CB 4.27Å; Q369-D393 WeakPolarHBondContact CG-OD2 3.48Å; Q369-D393 PolarHBondContact NE2-OD2 2.95Å; Q389-D393 VanDerWaalsContact NE2-CG 3.31Å; Q389-D393 PolarHBondContact NE2-OD1 3.34Å; Q389-D393 PolarHBondContact NE2-OD2 3.25Å; Q389-D393 VanDerWaalsContact NE2-OD2 3.14Å; Q389-D393 WeakPolarHBondContact O-CB 3.15Å; Q389-D393 VanDerWaalsContact O-CG 3.24Å; Q389-D393 PolarHBondContact O-N 2.95Å; I390-D393 PolarHBondContact O-N 3.08Å; D393-A395 VanDerWaalsContact C-N 3.28Å; D393-A395 PolarHBondContact O-N 3.18Å; D393-A396 WeakPolarHBondContact O-CB 3.37Å; D393-A396 PolarHBondContact O-N 3.32Å; D393-F397 HydrophobicContact CB-CE2 3.74Å; D393-F397 HydrophobicContact CB-CZ 3.75Å; D393-F397 WeakPolarHBondContact O-CD2 3.47Å; D393-F397 WeakPolarHBondContact O-CG 3.25Å; D393-F397 PolarHBondContact O-N 3.33Å
394M98.8Very high98.6Very high0 Ų039.1 Ų39.10%021%0.211CC..Hα-helixtrans-54.5-43.4173.3-73.7-62.1-65.300112.3V368 P373 L376 I390 A396 N398 P401 I403V368-M394 HydrophobicContact CG1-CG 4.27Å; V368-M394 HydrophobicContact CG1-SD 4.07Å; P373-M394 HydrophobicContact CG-CE 4.35Å; P373-M394 HydrophobicContact CG-SD 3.76Å; P373-M394 WeakPolarHBondContact O-CE 3.44Å; L376-M394 HydrophobicContact CB-CE 3.74Å; L376-M394 HydrophobicContact CB-SD 4.1Å; L376-M394 HydrophobicContact CD2-CG 4.21Å; I390-M394 HydrophobicContact CG2-CG 4.31Å; I390-M394 WeakPolarHBondContact O-CB 3.32Å; I390-M394 VanDerWaalsContact O-CG 3.32Å; I390-M394 WeakPolarHBondContact O-CG 3.28Å; I390-M394 PolarHBondContact O-N 3.44Å; M394-A396 VanDerWaalsContact C-N 3.33Å; M394-N398 WeakPolarHBondContact O-CB 3.39Å; M394-N398 PolarHBondContact O-N 3.18Å; M394-N398 VanDerWaalsContact O-N 3.13Å; M394-N398 PolarHBondContact O-ND2 3.09Å; M394-P401 HydrophobicContact CB-CB 3.96Å; M394-P401 HydrophobicContact CE-CB 4.13Å; M394-I403 HydrophobicContact CB-CD1 4.39Å
395A98.7Very high98.6Very high11 Ų1137 Ų379%0.09119%0.19CC..Hα-helixtrans-72.8-20.3177.900000114.7L391 K392 D393 N398 P401 T424 R427L391-A395 VanDerWaalsContact O-CB 3.31Å; L391-A395 WeakPolarHBondContact O-CB 3.34Å; L391-A395 PolarHBondContact O-N 2.9Å; L391-A395 VanDerWaalsContact O-N 3.12Å; K392-A395 CarbonylContact O-C 3.58Å; K392-A395 PolarHBondContact O-N 3.39Å; D393-A395 VanDerWaalsContact C-N 3.28Å; D393-A395 PolarHBondContact O-N 3.18Å; A395-N398 VanDerWaalsContact O-O 3.11Å; A395-P401 HydrophobicContact CB-CG 4.44Å; A395-T424 HydrophobicContact CB-CG2 3.86Å; A395-R427 HydrophobicContact CB-CG 4.47Å; A395-R427 PolarHBondContact O-NH1 2.87Å
396A98.7Very high98.5Very high77 Ų7736.8 Ų36.864%0.63619%0.185SC*.Hα-helixtrans-83.9-38.417500000111.5K392 D393 M394K392-A396 WeakPolarHBondContact O-CB 3.18Å; K392-A396 PolarHBondContact O-N 3.48Å; D393-A396 WeakPolarHBondContact O-CB 3.37Å; D393-A396 PolarHBondContact O-N 3.32Å; M394-A396 VanDerWaalsContact C-N 3.33Å
397F98.5Very high98.2Very high71 Ų7137.1 Ų37.131%0.31119%0.188SC..Hα-helixtrans-75.8-30.3179.5-51.7-28.7000112.7V368 Q369 K372 D393V368-F397 HydrophobicContact CG1-CE2 4.14Å; V368-F397 WeakPolarHBondContact O-CE2 3.39Å; Q369-F397 HydrophobicContact CG-CZ 4.3Å; K372-F397 HydrophobicContact CB-CD2 4Å; K372-F397 HydrophobicContact CB-CE2 4.43Å; K372-F397 HydrophobicContact CB-CG 4.24Å; K372-F397 HydrophobicContact CD-CD1 4.49Å; K372-F397 HydrophobicContact CG-CD1 4.42Å; K372-F397 HydrophobicContact CG-CD2 4.01Å; K372-F397 HydrophobicContact CG-CE1 4.44Å; K372-F397 HydrophobicContact CG-CE2 4.01Å; K372-F397 HydrophobicContact CG-CG 4.23Å; K372-F397 HydrophobicContact CG-CZ 4.25Å; D393-F397 HydrophobicContact CB-CE2 3.74Å; D393-F397 HydrophobicContact CB-CZ 3.75Å; D393-F397 WeakPolarHBondContact O-CD2 3.47Å; D393-F397 WeakPolarHBondContact O-CG 3.25Å; D393-F397 PolarHBondContact O-N 3.33Å
398N98.6Very high97.6Very high25 Ų2537.3 Ų37.313%0.13419%0.187CC..  trans-126.5138.3-171.7-52.7-77.5000111.4P373 T374 M394 A395 R400 P401P373-N398 PolarHBondContact O-ND2 3.22Å; T374-N398 WeakPolarHBondContact CA-OD1 3.39Å; T374-N398 WeakPolarHBondContact CG2-OD1 3.16Å; M394-N398 WeakPolarHBondContact O-CB 3.39Å; M394-N398 PolarHBondContact O-N 3.18Å; M394-N398 VanDerWaalsContact O-N 3.13Å; M394-N398 PolarHBondContact O-ND2 3.09Å; A395-N398 VanDerWaalsContact O-O 3.11Å; N398-R400 VanDerWaalsContact C-N 3.33Å; N398-R400 PolarHBondContact O-N 3.39Å; N398-P401 HydrophobicContact CB-CB 4.03Å
399E98.3Very high96.9Very high164 Ų16434.4 Ų34.477%0.76618%0.176SC*.SBendtrans-61.1-44.4172.3-172.6-176163.300111.2R427E399-R427 WeakPolarHBondContact O-CB 3.35Å; E399-R427 WeakPolarHBondContact O-CD 3.47Å
400R98.4Very high96.3Very high90 Ų9033.6 Ų33.634%0.3418%0.177SC..SBendtrans-131.680179.9-56.4-60.2-59.7-891.8109.4T288 N398 R427 I429T288-R400 HydrophobicContact CG2-CB 4.21Å; N398-R400 VanDerWaalsContact C-N 3.33Å; N398-R400 PolarHBondContact O-N 3.39Å; R400-R427 WeakPolarHBondContact CD-O 3.45Å; R400-R427 PolarHBondContact NE-O 2.84Å; R400-I429 HydrophobicContact CB-CD1 3.94Å; R400-I429 HydrophobicContact CB-CG1 4.29Å
401P98.8Very high95.6Very high0 Ų038 Ų380%021%0.208CC..  trans-66.4134.7-17828.2-31.8000110.7M394 A395 N398 I403 R427 A428 I429M394-P401 HydrophobicContact CB-CB 3.96Å; M394-P401 HydrophobicContact CE-CB 4.13Å; A395-P401 HydrophobicContact CB-CG 4.44Å; N398-P401 HydrophobicContact CB-CB 4.03Å; P401-I403 HydrophobicContact CB-CD1 4.34Å; P401-I403 HydrophobicContact CB-CG1 4.32Å; P401-I403 HydrophobicContact CG-CD1 4.32Å; P401-R427 HydrophobicContact CG-CG 4.32Å; P401-A428 HydrophobicContact CG-CB 4.27Å; P401-A428 WeakPolarHBondContact O-CA 3.24Å; P401-I429 PolarHBondContact O-N 3.16Å
402I98.9Very high95.3Very high1 Ų142 Ų421%0.00523%0.225CC..EExtended strand (participates in β ladder)trans-88.1123.8173.7-58.5169.5000108.2L281 A284 T288 T374 A375 L376 F404 I429L281-I402 HydrophobicContact CD2-CD1 4.33Å; L281-I402 HydrophobicContact CD2-CG2 3.99Å; A284-I402 HydrophobicContact CB-CD1 3.82Å; A284-I402 HydrophobicContact CB-CG1 4.12Å; T288-I402 HydrophobicContact CG2-CD1 4.42Å; T374-I402 PolarHBondContact O-N 3.05Å; T374-I402 VanDerWaalsContact O-N 3.08Å; A375-I402 CarbonylContact C-O 3.53Å; A375-I402 WeakPolarHBondContact CA-O 3.35Å; A375-I402 HydrophobicContact CB-CB 3.82Å; A375-I402 HydrophobicContact CB-CD1 4.38Å; A375-I402 HydrophobicContact CB-CG2 4.1Å; L376-I402 PolarHBondContact N-O 3.04Å; I402-F404 HydrophobicContact CG2-CD1 3.83Å; I402-F404 HydrophobicContact CG2-CE1 3.41Å; I402-F404 VanDerWaalsContact CG2-CE1 3.41Å; I402-F404 HydrophobicContact CG2-CZ 3.84Å; I402-I429 HydrophobicContact CG1-CB 4.36Å; I402-I429 HydrophobicContact CG1-CD1 4.16Å
403I98.9Very high95.1Very high0 Ų037.9 Ų37.90%021%0.209CC..EExtended strand (participates in β ladder)trans-133.2106.8-174.6-57.6177.7000108.9L376 F386 L391 M394 P401 T424 A428 I429 F430 A431L376-I403 WeakPolarHBondContact O-CA 3.5Å; F386-I403 HydrophobicContact CD2-CG2 3.85Å; F386-I403 HydrophobicContact CE2-CG2 4.12Å; L391-I403 HydrophobicContact CD2-CD1 3.67Å; L391-I403 HydrophobicContact CD2-CG2 4.2Å; M394-I403 HydrophobicContact CB-CD1 4.39Å; P401-I403 HydrophobicContact CB-CD1 4.34Å; P401-I403 HydrophobicContact CB-CG1 4.32Å; P401-I403 HydrophobicContact CG-CD1 4.32Å; I403-T424 HydrophobicContact CD1-CG2 4.19Å; I403-A428 HydrophobicContact CD1-CB 4.04Å; I403-I429 PolarHBondContact N-O 3.21Å; I403-F430 HydrophobicContact CB-CD2 4.33Å; I403-F430 HydrophobicContact CG2-CD2 4.13Å; I403-F430 HydrophobicContact CG2-CE2 4.46Å; I403-F430 WeakPolarHBondContact O-CA 3.42Å; I403-F430 VanDerWaalsContact O-CD2 3.25Å; I403-F430 WeakPolarHBondContact O-CD2 3.41Å; I403-A431 PolarHBondContact O-N 3.43Å
404F98.8Very high95.1Very high0 Ų036.9 Ų36.90%020%0.204CC..EExtended strand (participates in β ladder)trans-109.5114.2-179.9-713.2000110.2L281 L376 I377 G378 I402 L406 A431 L499L281-F404 HydrophobicContact CD2-CE2 3.89Å; L281-F404 HydrophobicContact CD2-CZ 4.04Å; L281-F404 HydrophobicContact CG-CE2 3.87Å; L281-F404 HydrophobicContact CG-CZ 4.31Å; L376-F404 PolarHBondContact O-N 3.03Å; I377-F404 CarbonylContact C-O 3.6Å; I377-F404 WeakPolarHBondContact CA-O 3.47Å; I377-F404 HydrophobicContact CB-CB 4.39Å; I377-F404 HydrophobicContact CD1-CD2 4.32Å; I377-F404 HydrophobicContact CG1-CB 4.18Å; I377-F404 HydrophobicContact CG1-CD2 4.25Å; I377-F404 HydrophobicContact CG1-CG 4.47Å; I377-F404 HydrophobicContact CG2-CB 4.11Å; G378-F404 PolarHBondContact N-O 2.75Å; I402-F404 HydrophobicContact CG2-CD1 3.83Å; I402-F404 HydrophobicContact CG2-CE1 3.41Å; I402-F404 VanDerWaalsContact CG2-CE1 3.41Å; I402-F404 HydrophobicContact CG2-CZ 3.84Å; F404-L406 HydrophobicContact CB-CD1 4.32Å; F404-L406 HydrophobicContact CB-CD2 4.01Å; F404-L406 HydrophobicContact CB-CG 3.94Å; F404-L406 HydrophobicContact CD2-CD1 4.48Å; F404-A431 CarbonylContact C-O 3.45Å; F404-A431 VanDerWaalsContact CA-O 3.32Å; F404-A431 WeakPolarHBondContact CA-O 3.43Å; F404-A431 HydrophobicContact CD1-CB 3.7Å; F404-A431 HydrophobicContact CE1-CB 3.81Å; F404-A431 HydrophobicContact CG-CB 4.3Å; F404-A431 HydrophobicContact CZ-CB 4.45Å; F404-L499 HydrophobicContact CD1-CD1 4.49Å; F404-L499 HydrophobicContact CE1-CD1 3.34Å; F404-L499 HydrophobicContact CZ-CD1 3.64Å
405A97.9Very high95Very high0 Ų037 Ų370%021%0.205CC..EExtended strand (participates in β ladder)trans-103.877176.700000110.1E414 F430 A431 S432 G433A405-E414 WeakPolarHBondContact CA-OE2 3.49Å; A405-E414 HydrophobicContact CB-CB 4.1Å; A405-F430 HydrophobicContact CB-CE2 3.9Å; A405-F430 HydrophobicContact CB-CZ 4.05Å; A405-A431 PolarHBondContact N-O 2.99Å; A405-S432 CarbonylContact O-C 3.53Å; A405-S432 WeakPolarHBondContact O-CA 3.36Å; A405-S432 WeakPolarHBondContact O-CB 3.46Å; A405-G433 PolarHBondContact O-N 3.25Å
406L96.3Very high95Very high16 Ų1638.2 Ų38.28%0.08421%0.212CC..  trans-88.2-3.7-164.9-54.2-178.6000114.1A277 I309 I377 G378 V379 F404 E414A277-L406 HydrophobicContact CB-CD1 4.23Å; I309-L406 HydrophobicContact CD1-CD1 4.22Å; I377-L406 HydrophobicContact CG2-CD1 3.88Å; I377-L406 HydrophobicContact CG2-CG 4.46Å; G378-L406 WeakPolarHBondContact O-CA 3.36Å; G378-L406 VanDerWaalsContact O-CB 3.31Å; G378-L406 WeakPolarHBondContact O-CB 3.26Å; G378-L406 PolarHBondContact O-N 3.02Å; V379-L406 HydrophobicContact CG1-CB 3.86Å; V379-L406 HydrophobicContact CG1-CD1 4.12Å; V379-L406 HydrophobicContact CG1-CG 4.47Å; F404-L406 HydrophobicContact CB-CD1 4.32Å; F404-L406 HydrophobicContact CB-CD2 4.01Å; F404-L406 HydrophobicContact CB-CG 3.94Å; F404-L406 HydrophobicContact CD2-CD1 4.48Å; L406-E414 PolarHBondContact N-OE2 3.33Å
407S91.1Very high95Very high8 Ų834.6 Ų34.66%0.05618%0.182CC..  trans-67138.9178.4-72.50000112.9A380 A381 K412 E414A380-S407 PolarHBondContact N-OG 3.27Å; A381-S407 WeakPolarHBondContact CA-OG 3.12Å; A381-S407 PolarHBondContact N-OG 3.33Å; S407-K412 WeakPolarHBondContact CB-O 3.06Å; S407-E414 VanDerWaalsContact CB-OE1 3.28Å; S407-E414 WeakPolarHBondContact CB-OE1 3.32Å; S407-E414 PolarHBondContact N-OE2 3.43Å; S407-E414 PolarHBondContact OG-OE1 2.83Å
408N85.3Confident95Very high30 Ų3036 Ų3616%0.1619%0.19CC..SBendtrans-116.7152.7178.7-67.2-55000111.2L157 G433 S434L157-N408 HydrophobicContact CD2-CB 3.85Å; L157-N408 HydrophobicContact CG-CB 4.34Å; N408-G433 PolarHBondContact OD1-O 3.18Å; N408-S434 PolarHBondContact OD1-N 3.27Å; N408-S434 VanDerWaalsContact OD1-N 3.08Å; N408-S434 PolarHBondContact OD1-OG 3.42Å
409P85Confident95Very high38 Ų3837.6 Ų37.625%0.24720%0.196CC..SBendcis-73.3-171.2-1233.3-37.4000112P104 S411 K412 S434P104-P409 HydrophobicContact CB-CB 4.02Å; P409-S411 PolarHBondContact O-N 3.18Å; P409-K412 WeakPolarHBondContact O-CA 3.29Å; P409-K412 WeakPolarHBondContact O-CB 3.48Å; P409-K412 PolarHBondContact O-N 3.2Å; P409-S434 VanDerWaalsContact C-OG 3.26Å; P409-S434 WeakPolarHBondContact CA-OG 3.5Å
410T85.7Confident95Very high59 Ų5929.8 Ų29.836%0.36216%0.16SC..G310 helixtrans-50.1-35-178.3-480000113.9K412 A413 S434 F436T410-K412 PolarHBondContact O-N 3.01Å; T410-K412 VanDerWaalsContact O-N 3.15Å; T410-A413 WeakPolarHBondContact O-CB 3.47Å; T410-A413 PolarHBondContact O-N 3.47Å; T410-A413 VanDerWaalsContact O-N 3.14Å; T410-S434 PolarHBondContact N-OG 3.19Å; T410-S434 VanDerWaalsContact N-OG 3.1Å; T410-S434 VanDerWaalsContact OG1-CB 3.32Å; T410-S434 WeakPolarHBondContact OG1-CB 3.48Å; T410-F436 HydrophobicContact CG2-CD1 4.32Å; T410-F436 HydrophobicContact CG2-CE1 3.49Å; T410-F436 VanDerWaalsContact CG2-CE1 3.49Å; T410-F436 HydrophobicContact CG2-CZ 3.62Å
411S85.3Confident95Very high94 Ų9425.6 Ų25.666%0.65714%0.144SC*.G310 helixtrans-66-12.817760.90000114.3P409P409-S411 PolarHBondContact O-N 3.18Å
412K91.8Very high95Very high83 Ų8334.5 Ų34.536%0.36118%0.178SC..G310 helixtrans-107.6-2.5177.2-59.2-58.8-171.4173.90113.2A381 S407 P409 T410A381-K412 HydrophobicContact CB-CB 4.27Å; A381-K412 HydrophobicContact CB-CG 4.49Å; S407-K412 WeakPolarHBondContact CB-O 3.06Å; P409-K412 WeakPolarHBondContact O-CA 3.29Å; P409-K412 WeakPolarHBondContact O-CB 3.48Å; P409-K412 PolarHBondContact O-N 3.2Å; T410-K412 PolarHBondContact O-N 3.01Å; T410-K412 VanDerWaalsContact O-N 3.15Å
413A94.4Very high94.9Very high8 Ų835.8 Ų35.87%0.06618%0.184CC..  trans-60.9136.2176.800000110.8G383 G384 T410 C415 F436G383-A413 WeakPolarHBondContact CA-O 3.47Å; G384-A413 PolarHBondContact N-O 2.99Å; G384-A413 VanDerWaalsContact N-O 3.11Å; T410-A413 WeakPolarHBondContact O-CB 3.47Å; T410-A413 PolarHBondContact O-N 3.47Å; T410-A413 VanDerWaalsContact O-N 3.14Å; A413-C415 PolarHBondContact O-N 2.84Å; A413-F436 HydrophobicContact CB-CE2 4.21Å; A413-F436 HydrophobicContact CB-CZ 3.93Å
414E98.4Very high94.9Very high0 Ų035.8 Ų35.80%018%0.184CC..SBendtrans-62.5-32-176.4-70.276.4-171.900112.6G378 V379 A380 G384 A385 F386 A405 L406 S407G378-E414 VanDerWaalsContact C-CD 3.46Å; G378-E414 VanDerWaalsContact CA-CD 3.46Å; G378-E414 VanDerWaalsContact CA-OE1 3.31Å; G378-E414 WeakPolarHBondContact CA-OE1 3.29Å; V379-E414 PolarHBondContact N-OE1 3.35Å; A380-E414 PolarHBondContact N-OE1 2.88Å; G384-E414 CarbonylContact C-O 3.5Å; G384-E414 WeakPolarHBondContact CA-O 3.38Å; G384-E414 PolarHBondContact N-O 2.98Å; A385-E414 HydrophobicContact CB-CB 4.47Å; A385-E414 HydrophobicContact CB-CG 4.31Å; A385-E414 PolarHBondContact N-O 2.84Å; A385-E414 VanDerWaalsContact N-O 3.08Å; F386-E414 HydrophobicContact CB-CB 4.25Å; F386-E414 HydrophobicContact CD1-CB 3.85Å; F386-E414 HydrophobicContact CD1-CG 4.28Å; F386-E414 HydrophobicContact CD2-CB 3.52Å; F386-E414 HydrophobicContact CD2-CG 4.42Å; F386-E414 HydrophobicContact CE1-CB 3.97Å; F386-E414 HydrophobicContact CE1-CG 3.96Å; F386-E414 HydrophobicContact CE2-CB 3.67Å; F386-E414 HydrophobicContact CE2-CG 4.13Å; F386-E414 HydrophobicContact CG-CB 3.61Å; F386-E414 HydrophobicContact CG-CG 4.49Å; F386-E414 HydrophobicContact CZ-CB 3.88Å; F386-E414 HydrophobicContact CZ-CG 3.88Å; F386-E414 PolarHBondContact N-O 3.26Å; A405-E414 WeakPolarHBondContact CA-OE2 3.49Å; A405-E414 HydrophobicContact CB-CB 4.1Å; L406-E414 PolarHBondContact N-OE2 3.33Å; S407-E414 VanDerWaalsContact CB-OE1 3.28Å; S407-E414 WeakPolarHBondContact CB-OE1 3.32Å; S407-E414 PolarHBondContact N-OE2 3.43Å; S407-E414 PolarHBondContact OG-OE1 2.83Å
415C98.3Very high94.9Very high3 Ų344.1 Ų44.12%0.0222%0.221CC..SBendtrans-155.7166164.861.20000110F386 L391 A413F386-C415 HydrophobicContact CB-CB 3.96Å; L391-C415 HydrophobicContact CD1-CB 4.42Å; A413-C415 PolarHBondContact O-N 2.84Å
416S98.4Very high94.8Very high36 Ų3644.9 Ų44.925%0.25223%0.228SC..  trans-85.6159.717170.60000112.1E418 Q419 C420S416-E418 VanDerWaalsContact C-N 3.32Å; S416-E418 PolarHBondContact O-N 2.93Å; S416-Q419 PolarHBondContact O-N 2.98Å; S416-Q419 VanDerWaalsContact OG-CB 3.3Å; S416-Q419 WeakPolarHBondContact OG-CB 3.22Å; S416-Q419 PolarHBondContact OG-N 3.48Å; S416-Q419 VanDerWaalsContact OG-N 3.13Å; S416-C420 WeakPolarHBondContact O-CB 3.42Å; S416-C420 PolarHBondContact O-N 3.02Å
417A98.2Very high94.9Very high1 Ų148.8 Ų48.81%0.00824%0.242CC..Hα-helixtrans-56.9-45.4172.300000112Q419 C420 Y421 F430 F436 V439 P449A417-Q419 PolarHBondContact O-N 3.48Å; A417-C420 PolarHBondContact O-N 3.16Å; A417-Y421 HydrophobicContact CB-CD2 4.33Å; A417-Y421 HydrophobicContact CB-CE2 4.09Å; A417-Y421 WeakPolarHBondContact O-CB 3.4Å; A417-Y421 WeakPolarHBondContact O-CD2 3.31Å; A417-Y421 PolarHBondContact O-N 3.22Å; A417-F430 HydrophobicContact CB-CD1 3.88Å; A417-F430 HydrophobicContact CB-CE1 3.61Å; A417-F430 HydrophobicContact CB-CZ 4.38Å; A417-F436 HydrophobicContact CB-CB 3.87Å; A417-F436 HydrophobicContact CB-CD2 4.43Å; A417-F436 HydrophobicContact CB-CG 4.14Å; A417-V439 HydrophobicContact CB-CG2 4.17Å; A417-P449 HydrophobicContact CB-CB 3.8Å; A417-P449 HydrophobicContact CB-CG 3.64Å
418E98.1Very high95.3Very high100 Ų10048.6 Ų48.647%0.46724%0.241SC..Hα-helixtrans-57.1-50.3177.5-177.964.2-146.400111.4S416 C420 R422 V439S416-E418 VanDerWaalsContact C-N 3.32Å; S416-E418 PolarHBondContact O-N 2.93Å; E418-C420 PolarHBondContact O-N 3.39Å; E418-R422 WeakPolarHBondContact O-CB 3.44Å; E418-R422 PolarHBondContact O-N 3.38Å; E418-V439 HydrophobicContact CB-CG2 4.28Å; E418-V439 WeakPolarHBondContact OE2-CG1 3.3Å; E418-V439 WeakPolarHBondContact OE2-CG2 3.39Å
419Q98.3Very high95.9Very high58 Ų5847.4 Ų47.427%0.27123%0.234SC..Hα-helixtrans-59.5-49.5178.4-179.4-173.7-2.800110.8F386 L391 S416 A417 I423F386-Q419 PolarHBondContact O-NE2 3.24Å; L391-Q419 HydrophobicContact CD1-CG 3.76Å; S416-Q419 PolarHBondContact O-N 2.98Å; S416-Q419 VanDerWaalsContact OG-CB 3.3Å; S416-Q419 WeakPolarHBondContact OG-CB 3.22Å; S416-Q419 PolarHBondContact OG-N 3.48Å; S416-Q419 VanDerWaalsContact OG-N 3.13Å; A417-Q419 PolarHBondContact O-N 3.48Å; Q419-I423 HydrophobicContact CG-CD1 3.59Å; Q419-I423 WeakPolarHBondContact O-CB 3.24Å; Q419-I423 WeakPolarHBondContact O-CD1 3.31Å; Q419-I423 WeakPolarHBondContact O-CG1 3.17Å; Q419-I423 PolarHBondContact O-N 2.93Å; Q419-I423 VanDerWaalsContact O-N 3.09Å
420C98.7Very high96.6Very high0 Ų045.7 Ų45.70%022%0.223CC..Hα-helixtrans-57.7-55.3-179.9-176.30000111.6S416 A417 E418 R422 T424 A428 F430S416-C420 WeakPolarHBondContact O-CB 3.42Å; S416-C420 PolarHBondContact O-N 3.02Å; A417-C420 PolarHBondContact O-N 3.16Å; E418-C420 PolarHBondContact O-N 3.39Å; C420-R422 PolarHBondContact O-N 3.08Å; C420-T424 WeakPolarHBondContact O-CB 3Å; C420-T424 VanDerWaalsContact O-CG2 3.26Å; C420-T424 WeakPolarHBondContact O-CG2 3.46Å; C420-T424 PolarHBondContact O-N 3.2Å; C420-T424 VanDerWaalsContact O-N 3.08Å; C420-T424 PolarHBondContact O-OG1 3.09Å; C420-A428 WeakPolarHBondContact SG-CB 3.27Å; C420-F430 HydrophobicContact CB-CD2 3.77Å; C420-F430 HydrophobicContact CB-CE2 4.08Å; C420-F430 HydrophobicContact CB-CG 4.32Å; C420-F430 VanDerWaalsContact SG-CD2 3.54Å
421Y98.6Very high97.2Very high2 Ų242.9 Ų42.91%0.00821%0.206CC..Hα-helixtrans-67.3-40.2-177.1-64.8-43.2000112.6A417 K425 G426 A428 F430 V439 L447 P449A417-Y421 HydrophobicContact CB-CD2 4.33Å; A417-Y421 HydrophobicContact CB-CE2 4.09Å; A417-Y421 WeakPolarHBondContact O-CB 3.4Å; A417-Y421 WeakPolarHBondContact O-CD2 3.31Å; A417-Y421 PolarHBondContact O-N 3.22Å; Y421-K425 CarbonylContact O-C 3.28Å; Y421-K425 WeakPolarHBondContact O-CA 3.34Å; Y421-K425 PolarHBondContact O-N 2.93Å; Y421-G426 PolarHBondContact O-N 3.25Å; Y421-A428 HydrophobicContact CD1-CB 4.44Å; Y421-F430 HydrophobicContact CD1-CB 4.48Å; Y421-F430 HydrophobicContact CE1-CB 3.62Å; Y421-V439 HydrophobicContact CD2-CB 3.78Å; Y421-V439 HydrophobicContact CD2-CG1 4Å; Y421-V439 HydrophobicContact CD2-CG2 3.94Å; Y421-V439 HydrophobicContact CE2-CB 4.32Å; Y421-V439 HydrophobicContact CE2-CG2 4.37Å; Y421-L447 HydrophobicContact CD1-CD1 3.68Å; Y421-L447 HydrophobicContact CD2-CB 4.31Å; Y421-L447 HydrophobicContact CD2-CD1 4.13Å; Y421-L447 HydrophobicContact CE1-CD1 3.66Å; Y421-L447 HydrophobicContact CE2-CB 3.82Å; Y421-L447 HydrophobicContact CE2-CD1 4.11Å; Y421-L447 HydrophobicContact CG-CD1 3.92Å; Y421-P449 HydrophobicContact CE2-CB 4.23Å
422R97.8Very high97.7Very high187 Ų18738.4 Ų38.471%0.70618%0.175SC*.Hα-helixtrans-62.6-49.2179.8-176.8-179.6126.6129.3-0111.9E418 C420 K425E418-R422 WeakPolarHBondContact O-CB 3.44Å; E418-R422 PolarHBondContact O-N 3.38Å; C420-R422 PolarHBondContact O-N 3.08Å; R422-K425 PolarHBondContact O-N 3.26Å
423I98.5Very high97.6Very high28 Ų2834.7 Ų34.714%0.14416%0.159CC..Hα-helixtrans-70.7-39.2-175.8-71.1158.8000111.3E388 L391 K392 Q419 K425E388-I423 HydrophobicContact CB-CD1 3.83Å; E388-I423 HydrophobicContact CG-CD1 3.74Å; E388-I423 HydrophobicContact CG-CG1 4.05Å; E388-I423 HydrophobicContact CG-CG2 4.23Å; L391-I423 HydrophobicContact CB-CB 4.21Å; L391-I423 HydrophobicContact CB-CG2 3.65Å; L391-I423 HydrophobicContact CD1-CB 4.46Å; L391-I423 HydrophobicContact CD1-CD1 3.8Å; K392-I423 HydrophobicContact CG-CG2 3.61Å; Q419-I423 HydrophobicContact CG-CD1 3.59Å; Q419-I423 WeakPolarHBondContact O-CB 3.24Å; Q419-I423 WeakPolarHBondContact O-CD1 3.31Å; Q419-I423 WeakPolarHBondContact O-CG1 3.17Å; Q419-I423 PolarHBondContact O-N 2.93Å; Q419-I423 VanDerWaalsContact O-N 3.09Å; I423-K425 PolarHBondContact O-N 3.09Å
424T98.6Very high97.2Very high0 Ų034.6 Ų34.60%016%0.158CC..Hα-helixtrans-80.5-2.1176.7680000112.9L391 A395 I403 C420 R427 A428L391-T424 HydrophobicContact CB-CG2 4.37Å; A395-T424 HydrophobicContact CB-CG2 3.86Å; I403-T424 HydrophobicContact CD1-CG2 4.19Å; C420-T424 WeakPolarHBondContact O-CB 3Å; C420-T424 VanDerWaalsContact O-CG2 3.26Å; C420-T424 WeakPolarHBondContact O-CG2 3.46Å; C420-T424 PolarHBondContact O-N 3.2Å; C420-T424 VanDerWaalsContact O-N 3.08Å; C420-T424 PolarHBondContact O-OG1 3.09Å; T424-R427 WeakPolarHBondContact O-CD 3.5Å; T424-R427 WeakPolarHBondContact O-CG 3.42Å; T424-R427 PolarHBondContact O-N 3.14Å; T424-R427 PolarHBondContact O-NE 3.16Å; T424-A428 HydrophobicContact CG2-CB 3.92Å; T424-A428 WeakPolarHBondContact OG1-CB 3.25Å; T424-A428 PolarHBondContact OG1-N 2.84Å
425K97.9Very high96.7Very high176 Ų17637 Ų3777%0.76517%0.174SC*.THydrogen-bonded Turntrans59.742.9-179.6-49.3176.8-177.9177.90112.6Y421 R422 I423 R427Y421-K425 CarbonylContact O-C 3.28Å; Y421-K425 WeakPolarHBondContact O-CA 3.34Å; Y421-K425 PolarHBondContact O-N 2.93Å; R422-K425 PolarHBondContact O-N 3.26Å; I423-K425 PolarHBondContact O-N 3.09Å; K425-R427 PolarHBondContact O-N 3.43Å
426G97.2Very high96.4Very high15 Ų1539 Ų3916%0.15518%0.182CC..THydrogen-bonded Turntrans76.7-0.5177.100000115.5Y421Y421-G426 PolarHBondContact O-N 3.25Å
427R97.6Very high96.2Very high99 Ų9943.9 Ų43.937%0.37421%0.205SC..  trans-82.1-23-177.280.6-175.247.7-151.5-18.2113.6A395 E399 R400 P401 T424 K425A395-R427 HydrophobicContact CB-CG 4.47Å; A395-R427 PolarHBondContact O-NH1 2.87Å; E399-R427 WeakPolarHBondContact O-CB 3.35Å; E399-R427 WeakPolarHBondContact O-CD 3.47Å; R400-R427 WeakPolarHBondContact CD-O 3.45Å; R400-R427 PolarHBondContact NE-O 2.84Å; P401-R427 HydrophobicContact CG-CG 4.32Å; T424-R427 WeakPolarHBondContact O-CD 3.5Å; T424-R427 WeakPolarHBondContact O-CG 3.42Å; T424-R427 PolarHBondContact O-N 3.14Å; T424-R427 PolarHBondContact O-NE 3.16Å; K425-R427 PolarHBondContact O-N 3.43Å
428A98.6Very high96.2Very high4 Ų447.1 Ų47.13%0.03323%0.226CC..  trans-61.5143.8-179.600000111.9P401 I403 C420 Y421 T424P401-A428 HydrophobicContact CG-CB 4.27Å; P401-A428 WeakPolarHBondContact O-CA 3.24Å; I403-A428 HydrophobicContact CD1-CB 4.04Å; C420-A428 WeakPolarHBondContact SG-CB 3.27Å; Y421-A428 HydrophobicContact CD1-CB 4.44Å; T424-A428 HydrophobicContact CG2-CB 3.92Å; T424-A428 WeakPolarHBondContact OG1-CB 3.25Å; T424-A428 PolarHBondContact OG1-N 2.84Å
429I98.8Very high96.2Very high5 Ų542.6 Ų42.63%0.02621%0.206CC..EExtended strand (participates in β ladder)trans-99.4107.1166.6-58.2170.1000105.8A284 I287 T288 R400 P401 I402 I403 L499A284-I429 HydrophobicContact CB-CD1 4.41Å; A284-I429 HydrophobicContact CB-CG2 3.92Å; I287-I429 HydrophobicContact CB-CD1 3.79Å; I287-I429 HydrophobicContact CD1-CD1 4.26Å; I287-I429 HydrophobicContact CD1-CG1 4.25Å; I287-I429 HydrophobicContact CD1-CG2 4.08Å; I287-I429 HydrophobicContact CG2-CD1 3.69Å; I287-I429 HydrophobicContact CG2-CG1 4.1Å; T288-I429 HydrophobicContact CG2-CD1 3.56Å; R400-I429 HydrophobicContact CB-CD1 3.94Å; R400-I429 HydrophobicContact CB-CG1 4.29Å; P401-I429 PolarHBondContact O-N 3.16Å; I402-I429 HydrophobicContact CG1-CB 4.36Å; I402-I429 HydrophobicContact CG1-CD1 4.16Å; I403-I429 PolarHBondContact N-O 3.21Å; I429-L499 HydrophobicContact CG2-CD1 3.62Å; I429-L499 HydrophobicContact CG2-CD2 3.64Å; I429-L499 HydrophobicContact CG2-CG 3.91Å
430F98.8Very high96.2Very high1 Ų144.2 Ų44.20%0.00422%0.22CC..EExtended strand (participates in β ladder)trans-113.7139.1-169.3-178.4-97.2000112.7I403 A405 A417 C420 Y421 F436 P449I403-F430 HydrophobicContact CB-CD2 4.33Å; I403-F430 HydrophobicContact CG2-CD2 4.13Å; I403-F430 HydrophobicContact CG2-CE2 4.46Å; I403-F430 WeakPolarHBondContact O-CA 3.42Å; I403-F430 VanDerWaalsContact O-CD2 3.25Å; I403-F430 WeakPolarHBondContact O-CD2 3.41Å; A405-F430 HydrophobicContact CB-CE2 3.9Å; A405-F430 HydrophobicContact CB-CZ 4.05Å; A417-F430 HydrophobicContact CB-CD1 3.88Å; A417-F430 HydrophobicContact CB-CE1 3.61Å; A417-F430 HydrophobicContact CB-CZ 4.38Å; C420-F430 HydrophobicContact CB-CD2 3.77Å; C420-F430 HydrophobicContact CB-CE2 4.08Å; C420-F430 HydrophobicContact CB-CG 4.32Å; C420-F430 VanDerWaalsContact SG-CD2 3.54Å; Y421-F430 HydrophobicContact CD1-CB 4.48Å; Y421-F430 HydrophobicContact CE1-CB 3.62Å; F430-F436 HydrophobicContact CE1-CD2 4.23Å; F430-F436 HydrophobicContact CZ-CD2 4.48Å; F430-F436 HydrophobicContact CZ-CE2 4.41Å; F430-P449 HydrophobicContact CD1-CB 3.69Å; F430-P449 HydrophobicContact CE1-CB 4.1Å
431A98.3Very high96.1Very high0 Ų045 Ų450%022%0.224CC..EExtended strand (participates in β ladder)trans-140.6158.6165.700000110.1I403 F404 A405 G450 L499 Y500I403-A431 PolarHBondContact O-N 3.43Å; F404-A431 CarbonylContact C-O 3.45Å; F404-A431 VanDerWaalsContact CA-O 3.32Å; F404-A431 WeakPolarHBondContact CA-O 3.43Å; F404-A431 HydrophobicContact CD1-CB 3.7Å; F404-A431 HydrophobicContact CE1-CB 3.81Å; F404-A431 HydrophobicContact CG-CB 4.3Å; F404-A431 HydrophobicContact CZ-CB 4.45Å; A405-A431 PolarHBondContact N-O 2.99Å; A431-G450 WeakPolarHBondContact CA-O 3.49Å; A431-L499 HydrophobicContact CB-CD1 4.08Å; A431-Y500 HydrophobicContact CB-CE2 3.82Å
432S95.8Very high96Very high1 Ų151.7 Ų51.71%0.00727%0.267CS..EExtended strand (participates in β ladder)trans-143162.4-179.250.70000112.3A405 S434 F436 G450 Q451 G452A405-S432 CarbonylContact O-C 3.53Å; A405-S432 WeakPolarHBondContact O-CA 3.36Å; A405-S432 WeakPolarHBondContact O-CB 3.46Å; S432-S434 PolarHBondContact OG-O 2.64Å; S432-F436 WeakPolarHBondContact OG-CD2 3.2Å; S432-G450 PolarHBondContact N-O 2.88Å; S432-G450 VanDerWaalsContact N-O 3.07Å; S432-Q451 CarbonylContact O-C 3.59Å; S432-Q451 VanDerWaalsContact O-CA 3.25Å; S432-Q451 WeakPolarHBondContact O-CA 3.46Å; S432-G452 PolarHBondContact O-N 3.12Å
433G89.9Confident95.7Very high4 Ų448.3 Ų48.34%0.04126%0.263CS..SBendtrans-76.9-41.7176.100000112A405 N408A405-G433 PolarHBondContact O-N 3.25Å; N408-G433 PolarHBondContact OD1-O 3.18Å
434S86.2Confident95.6Very high6 Ų649.7 Ų49.74%0.04229%0.285CS..SBendtrans-96.7155.1179-680000112N408 P409 T410 S432N408-S434 PolarHBondContact OD1-N 3.27Å; N408-S434 VanDerWaalsContact OD1-N 3.08Å; N408-S434 PolarHBondContact OD1-OG 3.42Å; P409-S434 VanDerWaalsContact C-OG 3.26Å; P409-S434 WeakPolarHBondContact CA-OG 3.5Å; T410-S434 PolarHBondContact N-OG 3.19Å; T410-S434 VanDerWaalsContact N-OG 3.1Å; T410-S434 VanDerWaalsContact OG1-CB 3.32Å; T410-S434 WeakPolarHBondContact OG1-CB 3.48Å; S432-S434 PolarHBondContact OG-O 2.64Å
435P88.4Confident95.5Very high50 Ų5053.7 Ų53.733%0.32530%0.304SS..  trans-63.5141.5177.424.9-34.3000113Q451P435-Q451 VanDerWaalsContact CB-NE2 3.32Å
436F92.7Very high95.5Very high46 Ų4647.3 Ų47.320%0.20228%0.279CS..  trans-130.4147.5164-74-75.5000109.9T410 A413 A417 F430 S432 P449T410-F436 HydrophobicContact CG2-CD1 4.32Å; T410-F436 HydrophobicContact CG2-CE1 3.49Å; T410-F436 VanDerWaalsContact CG2-CE1 3.49Å; T410-F436 HydrophobicContact CG2-CZ 3.62Å; A413-F436 HydrophobicContact CB-CE2 4.21Å; A413-F436 HydrophobicContact CB-CZ 3.93Å; A417-F436 HydrophobicContact CB-CB 3.87Å; A417-F436 HydrophobicContact CB-CD2 4.43Å; A417-F436 HydrophobicContact CB-CG 4.14Å; F430-F436 HydrophobicContact CE1-CD2 4.23Å; F430-F436 HydrophobicContact CZ-CD2 4.48Å; F430-F436 HydrophobicContact CZ-CE2 4.41Å; S432-F436 WeakPolarHBondContact OG-CD2 3.2Å; F436-P449 HydrophobicContact CB-CG 4.05Å
437D94.3Very high95.5Very high138 Ų13847 Ų4774%0.73827%0.274SS*.  trans-65.5158.4176.1-68.6-38000112.2
438P97.4Very high95.5Very high69 Ų6946 Ų4645%0.44827%0.271SS..  trans-59.1146.1171.9-21.233.4000112.3T446 L447 Y448P438-T446 HydrophobicContact CB-CG2 3.88Å; P438-L447 CarbonylContact C-O 3.57Å; P438-L447 WeakPolarHBondContact CA-O 3.31Å; P438-Y448 HydrophobicContact CB-CD1 3.71Å; P438-Y448 HydrophobicContact CB-CE1 3.8Å; P438-Y448 HydrophobicContact CB-CG 4.35Å; P438-Y448 HydrophobicContact CG-CD1 3.52Å; P438-Y448 HydrophobicContact CG-CE1 3.65Å
439V98.3Very high95.3Very high6 Ų646.4 Ų46.44%0.03627%0.273CS..EExtended strand (participates in β ladder)trans-116.6121.2-177.6173.80000109.9A417 E418 Y421 L441 T446 L447A417-V439 HydrophobicContact CB-CG2 4.17Å; E418-V439 HydrophobicContact CB-CG2 4.28Å; E418-V439 WeakPolarHBondContact OE2-CG1 3.3Å; E418-V439 WeakPolarHBondContact OE2-CG2 3.39Å; Y421-V439 HydrophobicContact CD2-CB 3.78Å; Y421-V439 HydrophobicContact CD2-CG1 4Å; Y421-V439 HydrophobicContact CD2-CG2 3.94Å; Y421-V439 HydrophobicContact CE2-CB 4.32Å; Y421-V439 HydrophobicContact CE2-CG2 4.37Å; V439-L441 HydrophobicContact CG1-CD2 4.23Å; V439-T446 WeakPolarHBondContact O-CA 3.4Å; V439-L447 PolarHBondContact N-O 2.96Å; V439-L447 PolarHBondContact O-N 3.17Å
440T98.3Very high95Very high92 Ų9246.6 Ų46.656%0.56428%0.276SS*.EExtended strand (participates in β ladder)trans-96.1118.2175.3-59.40000110.3T446T440-T446 PolarHBondContact OG1-OG1 2.67Å
441L96.5Very high94.6Very high16 Ų1648 Ų488%0.08428%0.283CS..  trans-79.1162.1-178.3-60.3-179.2000112.1V439 N443 G444 Q445 L447V439-L441 HydrophobicContact CG1-CD2 4.23Å; L441-N443 VanDerWaalsContact CB-OD1 3.25Å; L441-N443 WeakPolarHBondContact CB-OD1 3.48Å; L441-N443 PolarHBondContact O-N 3.2Å; L441-N443 VanDerWaalsContact O-N 3.08Å; L441-G444 PolarHBondContact O-N 3.13Å; L441-Q445 WeakPolarHBondContact CB-O 3.44Å; L441-Q445 PolarHBondContact N-O 3.07Å; L441-L447 HydrophobicContact CD1-CD1 3.92Å; L441-L447 HydrophobicContact CD1-CG 4.28Å; L441-L447 HydrophobicContact CG-CD1 4.45Å
442P95.8Very high94.3Very high142 Ų14248.3 Ų48.392%0.92229%0.286SS*.THydrogen-bonded Turntrans-59.3-21.3177.6-25.935.1000115.2G444P442-G444 PolarHBondContact O-N 2.94Å
443N92.4Very high93.9Very high116 Ų11648.9 Ų48.962%0.6229%0.289SS*.THydrogen-bonded Turntrans-82.21.3175.967.8-3.1000113.2L441 Q445L441-N443 VanDerWaalsContact CB-OD1 3.25Å; L441-N443 WeakPolarHBondContact CB-OD1 3.48Å; L441-N443 PolarHBondContact O-N 3.2Å; L441-N443 VanDerWaalsContact O-N 3.08Å; N443-Q445 VanDerWaalsContact C-N 3.34Å; N443-Q445 VanDerWaalsContact OD1-CB 3.27Å; N443-Q445 WeakPolarHBondContact OD1-CB 3.45Å; N443-Q445 PolarHBondContact OD1-N 2.7Å
444G95.4Very high94Very high58 Ų5849.9 Ų49.960%0.59829%0.293SS*.SBendtrans85.4-3.6-178.300000115.1L441 P442L441-G444 PolarHBondContact O-N 3.13Å; P442-G444 PolarHBondContact O-N 2.94Å
445Q96.2Very high94.4Very high84 Ų8449.6 Ų49.639%0.39329%0.291SS..PPolyproline II helixtrans-75.8131.3175.5-174.1179.511.600110.4L441 N443 L447 E495L441-Q445 WeakPolarHBondContact CB-O 3.44Å; L441-Q445 PolarHBondContact N-O 3.07Å; N443-Q445 VanDerWaalsContact C-N 3.34Å; N443-Q445 VanDerWaalsContact OD1-CB 3.27Å; N443-Q445 WeakPolarHBondContact OD1-CB 3.45Å; N443-Q445 PolarHBondContact OD1-N 2.7Å; Q445-L447 HydrophobicContact CG-CD2 4.24Å; Q445-E495 PolarHBondContact NE2-O 3.44Å
446T97.9Very high94.9Very high42 Ų4247.4 Ų47.426%0.25828%0.277SS..EExtended strand (participates in β ladder)trans-99.7125.7171.8-55.90000110P438 V439 T440 Y448P438-T446 HydrophobicContact CB-CG2 3.88Å; V439-T446 WeakPolarHBondContact O-CA 3.4Å; T440-T446 PolarHBondContact OG1-OG1 2.67Å; T446-Y448 HydrophobicContact CG2-CD2 4.38Å; T446-Y448 HydrophobicContact CG2-CE1 4.37Å; T446-Y448 HydrophobicContact CG2-CE2 3.78Å
447L98.1Very high95.2Very high8 Ų845.2 Ų45.24%0.04227%0.267CS..EExtended strand (participates in β ladder)trans-103.8140.6174.4-61.8179.9000110.4Y421 P438 V439 L441 Q445 P449 E496Y421-L447 HydrophobicContact CD1-CD1 3.68Å; Y421-L447 HydrophobicContact CD2-CB 4.31Å; Y421-L447 HydrophobicContact CD2-CD1 4.13Å; Y421-L447 HydrophobicContact CE1-CD1 3.66Å; Y421-L447 HydrophobicContact CE2-CB 3.82Å; Y421-L447 HydrophobicContact CE2-CD1 4.11Å; Y421-L447 HydrophobicContact CG-CD1 3.92Å; P438-L447 CarbonylContact C-O 3.57Å; P438-L447 WeakPolarHBondContact CA-O 3.31Å; V439-L447 PolarHBondContact N-O 2.96Å; V439-L447 PolarHBondContact O-N 3.17Å; L441-L447 HydrophobicContact CD1-CD1 3.92Å; L441-L447 HydrophobicContact CD1-CG 4.28Å; L441-L447 HydrophobicContact CG-CD1 4.45Å; Q445-L447 HydrophobicContact CG-CD2 4.24Å; L447-P449 WeakPolarHBondContact O-CD 3.43Å; L447-E496 CarbonylContact C-O 3.6Å; L447-E496 WeakPolarHBondContact CA-O 3.38Å
448Y97.4Very high95.4Very high78 Ų7838.7 Ų38.731%0.30623%0.232SC..  trans-115.691.7-178.5-62.2-98.1000108.7P438 T446 G450 E496 R498P438-Y448 HydrophobicContact CB-CD1 3.71Å; P438-Y448 HydrophobicContact CB-CE1 3.8Å; P438-Y448 HydrophobicContact CB-CG 4.35Å; P438-Y448 HydrophobicContact CG-CD1 3.52Å; P438-Y448 HydrophobicContact CG-CE1 3.65Å; T446-Y448 HydrophobicContact CG2-CD2 4.38Å; T446-Y448 HydrophobicContact CG2-CE1 4.37Å; T446-Y448 HydrophobicContact CG2-CE2 3.78Å; Y448-G450 PolarHBondContact O-N 3.04Å; Y448-E496 HydrophobicContact CD2-CB 3.96Å; Y448-E496 HydrophobicContact CD2-CG 4.26Å; Y448-E496 HydrophobicContact CE2-CG 4.43Å; Y448-E496 PolarHBondContact N-O 2.99Å; Y448-R498 VanDerWaalsContact CG-CZ 3.45Å; Y448-R498 VanDerWaalsContact O-CG 3.29Å; Y448-R498 WeakPolarHBondContact O-CG 3.27Å
449P95.3Very high95.5Very high13 Ų1335.4 Ų35.48%0.08421%0.211CC..  trans-60.7127.9-17527.7-35.8000111A417 Y421 F430 F436 L447A417-P449 HydrophobicContact CB-CB 3.8Å; A417-P449 HydrophobicContact CB-CG 3.64Å; Y421-P449 HydrophobicContact CE2-CB 4.23Å; F430-P449 HydrophobicContact CD1-CB 3.69Å; F430-P449 HydrophobicContact CE1-CB 4.1Å; F436-P449 HydrophobicContact CB-CG 4.05Å; L447-P449 WeakPolarHBondContact O-CD 3.43Å
450G90.9Very high95.5Very high8 Ų835.1 Ų35.18%0.08221%0.209CC..EExtended strand (participates in β ladder)trans-74.7151.2179.600000112.8A431 S432 Y448A431-G450 WeakPolarHBondContact CA-O 3.49Å; S432-G450 PolarHBondContact N-O 2.88Å; S432-G450 VanDerWaalsContact N-O 3.07Å; Y448-G450 PolarHBondContact O-N 3.04Å
451Q91.8Very high95.5Very high30 Ų3030.7 Ų30.714%0.1418%0.182CC..EExtended strand (participates in β ladder)trans-101115.5172.7-68.7172.547.800110.5S432 P435 N453 Y456 Y500S432-Q451 CarbonylContact O-C 3.59Å; S432-Q451 VanDerWaalsContact O-CA 3.25Å; S432-Q451 WeakPolarHBondContact O-CA 3.46Å; P435-Q451 VanDerWaalsContact CB-NE2 3.32Å; Q451-N453 HydrophobicContact CB-CB 4.46Å; Q451-N453 PolarHBondContact O-N 2.77Å; Q451-Y456 WeakPolarHBondContact O-CE2 3.32Å; Q451-Y500 WeakPolarHBondContact O-CD2 3.04Å
452G90.9Very high95.6Very high7 Ų730 Ų307%0.07218%0.178CC..  trans-76.559.1171.200000111.4S432 Y500S432-G452 PolarHBondContact O-N 3.12Å; G452-Y500 VanDerWaalsContact CA-CE2 3.49Å; G452-Y500 VanDerWaalsContact CA-CZ 3.47Å
453N86.9Confident95.8Very high13 Ų1323.5 Ų23.57%0.0714%0.136CC..  trans-88.4131.4-175.3-169-46.3000110.9Q451 S455 Y456Q451-N453 HydrophobicContact CB-CB 4.46Å; Q451-N453 PolarHBondContact O-N 2.77Å; N453-S455 PolarHBondContact O-N 2.85Å; N453-S455 VanDerWaalsContact OD1-CB 3.22Å; N453-S455 WeakPolarHBondContact OD1-CB 3.38Å; N453-S455 PolarHBondContact OD1-N 3.05Å; N453-S455 PolarHBondContact OD1-OG 3.17Å; N453-Y456 WeakPolarHBondContact O-CD2 3.45Å; N453-Y456 PolarHBondContact O-N 3.19Å
454N93.3Very high96.1Very high25 Ų2518 Ų1813%0.13411%0.106CC..G310 helixtrans-56.8-18178.5-64.623.8000113.3D268 T273 Y456 V457 F458D268-N454 PolarHBondContact O-ND2 2.91Å; D268-N454 WeakPolarHBondContact OD2-CB 3.25Å; D268-N454 PolarHBondContact OD2-ND2 2.88Å; T273-N454 PolarHBondContact N-ND2 2.9Å; T273-N454 PolarHBondContact OG1-ND2 3.31Å; N454-Y456 PolarHBondContact O-N 3.27Å; N454-Y456 VanDerWaalsContact O-N 3.09Å; N454-V457 PolarHBondContact O-N 2.89Å; N454-F458 HydrophobicContact CB-CD1 4.07Å; N454-F458 HydrophobicContact CB-CE1 4.26Å; N454-F458 WeakPolarHBondContact O-CD1 3.38Å; N454-F458 PolarHBondContact O-N 3.3Å
455S95.3Very high96.3Very high0 Ų015.2 Ų15.20%08%0.078CC..G310 helixtrans-57.8-17.1172.4-55.80000114.3L176 N453 V457 F458 P459 I506L176-S455 WeakPolarHBondContact CD1-OG 3.32Å; N453-S455 PolarHBondContact O-N 2.85Å; N453-S455 VanDerWaalsContact OD1-CB 3.22Å; N453-S455 WeakPolarHBondContact OD1-CB 3.38Å; N453-S455 PolarHBondContact OD1-N 3.05Å; N453-S455 PolarHBondContact OD1-OG 3.17Å; S455-V457 VanDerWaalsContact C-N 3.29Å; S455-F458 VanDerWaalsContact CA-CE1 3.48Å; S455-P459 WeakPolarHBondContact O-CD 3.48Å; S455-P459 WeakPolarHBondContact O-CG 3.41Å; S455-I506 WeakPolarHBondContact O-CD1 3.45Å
456Y98Very high96.4Very high5 Ų512 Ų122%0.026%0.064CC..G310 helixtrans-73.5-19.2168.8-74.2-74.2000113.8V276 Q451 N453 N454 Y500 P501 L503 I506 V509 I513V276-Y456 HydrophobicContact CG2-CD2 4.4Å; Q451-Y456 WeakPolarHBondContact O-CE2 3.32Å; N453-Y456 WeakPolarHBondContact O-CD2 3.45Å; N453-Y456 PolarHBondContact O-N 3.19Å; N454-Y456 PolarHBondContact O-N 3.27Å; N454-Y456 VanDerWaalsContact O-N 3.09Å; Y456-Y500 HydrophobicContact CE2-CG 4.44Å; Y456-P501 HydrophobicContact CE1-CB 4.38Å; Y456-P501 PolarHBondContact OH-O 2.69Å; Y456-L503 HydrophobicContact CE2-CD2 4.07Å; Y456-L503 VanDerWaalsContact OH-CD2 3.26Å; Y456-L503 WeakPolarHBondContact OH-CD2 3.46Å; Y456-L503 WeakPolarHBondContact OH-CG 3.36Å; Y456-I506 HydrophobicContact CD1-CD1 3.13Å; Y456-I506 HydrophobicContact CE1-CD1 3.4Å; Y456-I506 HydrophobicContact CG-CD1 3.76Å; Y456-V509 HydrophobicContact CD1-CG1 4.41Å; Y456-I513 WeakPolarHBondContact O-CD1 3.47Å
457V98.8Very high96.4Very high0 Ų010 Ų100%05%0.052CC..THydrogen-bonded Turntrans-109.5-68.1-167.6-179.80000110.9V276 N454 S455 P459 G460 V461 F478 T481 I485V276-V457 HydrophobicContact CB-CG2 3.84Å; N454-V457 PolarHBondContact O-N 2.89Å; S455-V457 VanDerWaalsContact C-N 3.29Å; V457-P459 VanDerWaalsContact C-N 3.32Å; V457-P459 VanDerWaalsContact O-N 3.16Å; V457-G460 PolarHBondContact O-N 3.06Å; V457-V461 HydrophobicContact CG1-CG2 3.86Å; V457-V461 WeakPolarHBondContact O-CG2 3.44Å; V457-V461 PolarHBondContact O-N 3.48Å; V457-F478 HydrophobicContact CG1-CD1 4.04Å; V457-F478 HydrophobicContact CG1-CE1 4.24Å; V457-T481 HydrophobicContact CB-CG2 4.44Å; V457-T481 HydrophobicContact CG1-CG2 3.97Å; V457-T481 HydrophobicContact CG2-CG2 4.4Å; V457-I485 HydrophobicContact CG2-CD1 3.78Å
458F98.6Very high96.4Very high0 Ų09.6 Ų9.60%05%0.05CC..Hα-helixtrans-56.8-35.2-168.966.4-103.8000114.4K173 L176 Y177 F266 D268 N454 S455 A462K173-F458 HydrophobicContact CG-CD2 4.46Å; K173-F458 HydrophobicContact CG-CE1 4.34Å; K173-F458 HydrophobicContact CG-CE2 4.03Å; K173-F458 HydrophobicContact CG-CZ 3.98Å; L176-F458 HydrophobicContact CB-CE2 3.82Å; L176-F458 HydrophobicContact CB-CZ 3.76Å; L176-F458 HydrophobicContact CD1-CZ 4.05Å; Y177-F458 AromaticContact CD2-CD2 3.35Å; Y177-F458 HydrophobicContact CD2-CD2 3.35Å; Y177-F458 AromaticContact CD2-CE2 3.54Å; Y177-F458 HydrophobicContact CD2-CE2 3.54Å; Y177-F458 HydrophobicContact CE2-CB 4.25Å; Y177-F458 AromaticContact CE2-CD2 3.18Å; Y177-F458 HydrophobicContact CE2-CD2 3.18Å; Y177-F458 AromaticContact CE2-CE2 3.78Å; Y177-F458 HydrophobicContact CE2-CE2 3.78Å; Y177-F458 AromaticContact CE2-CG 3.99Å; Y177-F458 HydrophobicContact CE2-CG 3.99Å; Y177-F458 HydrophobicContact CG-CD2 4.44Å; F266-F458 HydrophobicContact CE2-CB 4.45Å; F266-F458 HydrophobicContact CZ-CB 4.12Å; D268-F458 WeakPolarHBondContact OD1-CB 3.29Å; N454-F458 HydrophobicContact CB-CD1 4.07Å; N454-F458 HydrophobicContact CB-CE1 4.26Å; N454-F458 WeakPolarHBondContact O-CD1 3.38Å; N454-F458 PolarHBondContact O-N 3.3Å; S455-F458 VanDerWaalsContact CA-CE1 3.48Å; F458-A462 WeakPolarHBondContact O-CB 3.16Å; F458-A462 PolarHBondContact O-N 3.08Å
459P98.8Very high96.5Very high0 Ų06.1 Ų6.10%04%0.037CC..Hα-helixtrans-68.6-42.7-178.5-1528.7000112.1C180 G181 S455 V457 L463C180-P459 HydrophobicContact CB-CB 3.88Å; C180-P459 HydrophobicContact CB-CG 3.69Å; G181-P459 VanDerWaalsContact N-CB 3.31Å; S455-P459 WeakPolarHBondContact O-CD 3.48Å; S455-P459 WeakPolarHBondContact O-CG 3.41Å; V457-P459 VanDerWaalsContact C-N 3.32Å; V457-P459 VanDerWaalsContact O-N 3.16Å; P459-L463 VanDerWaalsContact O-CB 3.32Å; P459-L463 WeakPolarHBondContact O-CB 3.36Å; P459-L463 PolarHBondContact O-N 3.24Å
460G98.8Very high96.6Very high0 Ų05.7 Ų5.70%03%0.034CC..Hα-helixtrans-69.9-40.8177.500000112.7V457 L463 G464 S510V457-G460 PolarHBondContact O-N 3.06Å; G460-L463 PolarHBondContact O-N 2.95Å; G460-G464 PolarHBondContact O-N 3.08Å; G460-S510 WeakPolarHBondContact CA-O 3.38Å
461V98.9Very high96.8Very high0 Ų011.6 Ų11.60%05%0.054CC..Hα-helixtrans-61.8-50.9175.4172.20000110.5V457 L463 G464 V465 I477 F478 T481 I513 I517V457-V461 HydrophobicContact CG1-CG2 3.86Å; V457-V461 WeakPolarHBondContact O-CG2 3.44Å; V457-V461 PolarHBondContact O-N 3.48Å; V461-L463 VanDerWaalsContact C-N 3.34Å; V461-L463 PolarHBondContact O-N 3.12Å; V461-G464 PolarHBondContact O-N 3.49Å; V461-V465 HydrophobicContact CG1-CG2 4.13Å; V461-V465 WeakPolarHBondContact O-CB 3.31Å; V461-V465 VanDerWaalsContact O-CG2 3.25Å; V461-V465 WeakPolarHBondContact O-CG2 3.43Å; V461-V465 PolarHBondContact O-N 2.99Å; V461-I477 HydrophobicContact CG1-CG2 4.26Å; V461-I477 HydrophobicContact CG2-CG2 4.46Å; V461-F478 HydrophobicContact CG1-CE1 4.36Å; V461-F478 HydrophobicContact CG1-CZ 4.5Å; V461-F478 HydrophobicContact CG2-CE1 4.36Å; V461-T481 HydrophobicContact CG2-CG2 4.07Å; V461-I513 HydrophobicContact CG2-CG2 4.27Å; V461-I517 HydrophobicContact CB-CD1 4.37Å; V461-I517 HydrophobicContact CG2-CD1 4.23Å
462A98.9Very high97.1Very high0 Ų012.8 Ų12.80%06%0.06CC..Hα-helixtrans-59.4-45.1178.700000111.9Y177 M183 L241 F458 G464 V466Y177-A462 HydrophobicContact CD1-CB 3.65Å; Y177-A462 HydrophobicContact CE1-CB 3.18Å; M183-A462 VanDerWaalsContact CE-C 3.45Å; M183-A462 HydrophobicContact CE-CB 3.93Å; M183-A462 WeakPolarHBondContact CE-O 3.35Å; L241-A462 HydrophobicContact CD2-CB 3.54Å; F458-A462 WeakPolarHBondContact O-CB 3.16Å; F458-A462 PolarHBondContact O-N 3.08Å; A462-G464 PolarHBondContact O-N 3.12Å; A462-V466 VanDerWaalsContact O-CB 3.29Å; A462-V466 WeakPolarHBondContact O-CB 3.11Å; A462-V466 VanDerWaalsContact O-CG2 3.25Å; A462-V466 WeakPolarHBondContact O-CG2 3.44Å; A462-V466 PolarHBondContact O-N 3.39Å
463L98.9Very high97.4Very high6 Ų612.6 Ų12.63%0.0316%0.057CC..Hα-helixtrans-57.9-49.2176.1-179.768.4000111.4G181 P459 G460 V461 A467 A514 V540 M544G181-L463 VanDerWaalsContact O-CD2 3.3Å; G181-L463 WeakPolarHBondContact O-CD2 3.37Å; P459-L463 VanDerWaalsContact O-CB 3.32Å; P459-L463 WeakPolarHBondContact O-CB 3.36Å; P459-L463 PolarHBondContact O-N 3.24Å; G460-L463 PolarHBondContact O-N 2.95Å; V461-L463 VanDerWaalsContact C-N 3.34Å; V461-L463 PolarHBondContact O-N 3.12Å; L463-A467 WeakPolarHBondContact O-CB 3.39Å; L463-A467 PolarHBondContact O-N 3.4Å; L463-A514 HydrophobicContact CB-CB 3.96Å; L463-A514 HydrophobicContact CD2-CB 3.58Å; L463-A514 HydrophobicContact CG-CB 3.72Å; L463-V540 HydrophobicContact CD1-CG1 4.47Å; L463-V540 HydrophobicContact CD2-CG1 3.49Å; L463-V540 VanDerWaalsContact CD2-CG1 3.49Å; L463-V540 HydrophobicContact CG-CG1 3.95Å; L463-M544 HydrophobicContact CD1-CG 4.18Å; L463-M544 HydrophobicContact CD2-CE 4.23Å; L463-M544 HydrophobicContact CD2-CG 3.91Å; L463-M544 HydrophobicContact CD2-SD 4.16Å
464G98.8Very high97.9Very high0 Ų015.3 Ų15.30%07%0.074CC..Hα-helixtrans-63-48.6-179.400000113G460 V461 A462 A467 C468G460-G464 PolarHBondContact O-N 3.08Å; V461-G464 PolarHBondContact O-N 3.49Å; A462-G464 PolarHBondContact O-N 3.12Å; G464-A467 PolarHBondContact O-N 2.91Å; G464-C468 PolarHBondContact O-N 2.98Å; G464-C468 VanDerWaalsContact O-N 3.13Å; G464-C468 PolarHBondContact O-SG 3.08Å
465V98.8Very high98.1Very high1 Ų115.2 Ų15.21%0.0067%0.074CC..Hα-helixtrans-57.8-51.2178.4165.60000110.9L241 C264 V461 A467 G469 L470 I473L241-V465 HydrophobicContact CD1-CG1 4.37Å; C264-V465 WeakPolarHBondContact SG-CG1 3.13Å; V461-V465 HydrophobicContact CG1-CG2 4.13Å; V461-V465 WeakPolarHBondContact O-CB 3.31Å; V461-V465 VanDerWaalsContact O-CG2 3.25Å; V461-V465 WeakPolarHBondContact O-CG2 3.43Å; V461-V465 PolarHBondContact O-N 2.99Å; V465-A467 PolarHBondContact O-N 3.34Å; V465-G469 WeakPolarHBondContact O-CA 3.32Å; V465-G469 PolarHBondContact O-N 3.19Å; V465-L470 HydrophobicContact CB-CB 4.41Å; V465-L470 HydrophobicContact CG1-CB 4.19Å; V465-L470 HydrophobicContact CG2-CB 4.36Å; V465-L470 HydrophobicContact CG2-CD2 4.07Å; V465-L470 PolarHBondContact O-N 2.99Å; V465-I473 HydrophobicContact CG1-CD1 4.27Å; V465-I473 HydrophobicContact CG1-CG1 4.46Å; V465-I473 HydrophobicContact CG2-CD1 3.99Å; V465-I473 HydrophobicContact CG2-CG1 3.98Å
466V98.8Very high98.2Very high15 Ų1519.5 Ų19.59%0.0919%0.092CC..Hα-helixtrans-67.8-36.8-179.1171.60000111.7K146 M183 L241 A462K146-V466 HydrophobicContact CB-CG1 3.83Å; K146-V466 HydrophobicContact CB-CG2 4.36Å; K146-V466 HydrophobicContact CD-CG1 3.53Å; K146-V466 HydrophobicContact CG-CG1 4.35Å; M183-V466 HydrophobicContact CE-CB 3.96Å; M183-V466 HydrophobicContact CE-CG1 4.4Å; M183-V466 HydrophobicContact CE-CG2 3.84Å; M183-V466 HydrophobicContact SD-CB 4.33Å; M183-V466 HydrophobicContact SD-CG1 4.1Å; M183-V466 HydrophobicContact SD-CG2 4.36Å; L241-V466 HydrophobicContact CB-CG2 4.23Å; L241-V466 HydrophobicContact CD2-CG2 4.44Å; A462-V466 VanDerWaalsContact O-CB 3.29Å; A462-V466 WeakPolarHBondContact O-CB 3.11Å; A462-V466 VanDerWaalsContact O-CG2 3.25Å; A462-V466 WeakPolarHBondContact O-CG2 3.44Å; A462-V466 PolarHBondContact O-N 3.39Å
467A98.8Very high98.3Very high1 Ų120.2 Ų20.21%0.00810%0.096CC..Hα-helixtrans-68.4-39.7-177.500000113L463 G464 V465 V518 F539L463-A467 WeakPolarHBondContact O-CB 3.39Å; L463-A467 PolarHBondContact O-N 3.4Å; G464-A467 PolarHBondContact O-N 2.91Å; V465-A467 PolarHBondContact O-N 3.34Å; A467-V518 HydrophobicContact CB-CG2 4.19Å; A467-F539 HydrophobicContact CB-CE1 4.19Å; A467-F539 VanDerWaalsContact O-CE1 3.32Å; A467-F539 WeakPolarHBondContact O-CE1 3.22Å; A467-F539 VanDerWaalsContact O-CZ 3.23Å; A467-F539 WeakPolarHBondContact O-CZ 3.42Å
468C98.7Very high98.3Very high0 Ų020.2 Ų20.20%010%0.096CC..Hα-helixtrans-96.5-4.4178670000114.4G464 V518 A521 Y522 A527 T528 V529G464-C468 PolarHBondContact O-N 2.98Å; G464-C468 VanDerWaalsContact O-N 3.13Å; G464-C468 PolarHBondContact O-SG 3.08Å; C468-V518 HydrophobicContact CB-CB 4.41Å; C468-V518 HydrophobicContact CB-CG1 4.28Å; C468-V518 HydrophobicContact CB-CG2 3.97Å; C468-A521 HydrophobicContact CB-CB 4.43Å; C468-Y522 HydrophobicContact CB-CE2 4.45Å; C468-A527 HydrophobicContact CB-CB 4.05Å; C468-T528 PolarHBondContact O-N 2.85Å; C468-V529 PolarHBondContact O-N 3.12Å; C468-V529 VanDerWaalsContact O-N 3.11Å
469G98.4Very high98.3Very high4 Ų420.6 Ų20.64%0.04110%0.098CC..THydrogen-bonded Turntrans63.747.8-176.100000111.6V465 R471 T528V465-G469 WeakPolarHBondContact O-CA 3.32Å; V465-G469 PolarHBondContact O-N 3.19Å; G469-R471 PolarHBondContact O-N 3.14Å; G469-T528 WeakPolarHBondContact CA-OG1 3.46Å; G469-T528 WeakPolarHBondContact O-CB 3.38Å; G469-T528 WeakPolarHBondContact O-CG2 3.38Å; G469-T528 PolarHBondContact O-N 2.94Å; G469-T528 PolarHBondContact O-OG1 3.25Å
470L98Very high98.3Very high5 Ų521.1 Ų21.13%0.02610%0.101CC..  trans-67.2129.7177.6-164.272.3000109.6C264 V465 H472 I477 A521 T526C264-L470 PolarHBondContact SG-O 3.26Å; C264-L470 VanDerWaalsContact SG-O 3.33Å; V465-L470 HydrophobicContact CB-CB 4.41Å; V465-L470 HydrophobicContact CG1-CB 4.19Å; V465-L470 HydrophobicContact CG2-CB 4.36Å; V465-L470 HydrophobicContact CG2-CD2 4.07Å; V465-L470 PolarHBondContact O-N 2.99Å; L470-H472 WeakPolarHBondContact CD2-O 3.47Å; L470-H472 WeakPolarHBondContact CG-O 3.36Å; L470-I477 HydrophobicContact CD2-CD1 4.09Å; L470-I477 HydrophobicContact CD2-CG1 4.21Å; L470-A521 HydrophobicContact CD1-CB 3.84Å; L470-T526 WeakPolarHBondContact CD1-OG1 3.44Å
471R95.3Very high98.3Very high132 Ų13221.2 Ų21.250%0.49810%0.102SC..SBendtrans-81.2-31.8-175-69-18059.8-159.9-4.8114.6Y263 C264 G469 T528Y263-R471 CarbonylContact C-O 3.55Å; C264-R471 VanDerWaalsContact CA-O 3.22Å; C264-R471 WeakPolarHBondContact CA-O 3.41Å; C264-R471 WeakPolarHBondContact CB-O 3.34Å; C264-R471 PolarHBondContact N-O 2.71Å; G469-R471 PolarHBondContact O-N 3.14Å; R471-T528 HydrophobicContact CG-CG2 3.65Å
472H96.9Very high98.3Very high55 Ų5521.2 Ų21.226%0.25510%0.102SC..  trans-140.9141.4-177.3-56.5-61.7000109.9N261 Y263 L470N261-H472 PolarHBondContact O-CE1 3.22Å; Y263-H472 PolarHBondContact O-ND1 3.14Å; L470-H472 WeakPolarHBondContact CD2-O 3.47Å; L470-H472 WeakPolarHBondContact CG-O 3.36Å
473I98.4Very high98.3Very high2 Ų224.2 Ų24.21%0.0112%0.116CC..  trans-104.8103.2-177.4-51.6172.5000108.4L241 F266 V465 I477 F478L241-I473 HydrophobicContact CD1-CD1 3.57Å; F266-I473 HydrophobicContact CB-CD1 4.11Å; F266-I473 HydrophobicContact CD1-CD1 3.53Å; F266-I473 HydrophobicContact CE1-CD1 4.33Å; F266-I473 HydrophobicContact CG-CD1 4.2Å; V465-I473 HydrophobicContact CG1-CD1 4.27Å; V465-I473 HydrophobicContact CG1-CG1 4.46Å; V465-I473 HydrophobicContact CG2-CD1 3.99Å; V465-I473 HydrophobicContact CG2-CG1 3.98Å; I473-I477 HydrophobicContact CG2-CB 4.18Å; I473-I477 HydrophobicContact CG2-CG1 4.4Å; I473-I477 HydrophobicContact CG2-CG2 4.21Å; I473-F478 HydrophobicContact CG2-CD2 4.35Å; I473-F478 HydrophobicContact CG2-CE2 3.45Å; I473-F478 VanDerWaalsContact CG2-CE2 3.45Å; I473-F478 HydrophobicContact CG2-CZ 3.76Å
474T97.5Very high98.3Very high71 Ų7124.9 Ų24.944%0.43612%0.12SC..  trans-84.1159.5-179.765.90000111.2K476 I477T474-K476 PolarHBondContact O-N 3.4Å; T474-K476 VanDerWaalsContact O-N 3.13Å; T474-I477 WeakPolarHBondContact O-CB 3.5Å; T474-I477 PolarHBondContact O-N 3.27Å
475D97.1Very high98.3Very high23 Ų2324.9 Ų24.912%0.12312%0.12CC..Hα-helixtrans-62.1-22.7177.1-64.3-31.1000112.6R260 Q271 H311 L312 M315 I477 F478 L479R260-D475 IonicContact CZ-OD1 2.55Å; R260-D475 IonicContact CZ-OD2 3.93Å; R260-D475 IonicContact NH1-OD2 2.98Å; R260-D475 IonicContact NH2-OD1 3.87Å; R260-D475 PolarHBondContact NH2-OD1 2.89Å; R260-D475 IonicContact NH2-OD2 2.85Å; R260-D475 PolarHBondContact NH2-OD2 2.88Å; Q271-D475 PolarHBondContact NE2-OD1 2.65Å; H311-D475 IonicContact CD2-OD2 3.72Å; H311-D475 IonicContact CE1-OD2 2.6Å; H311-D475 IonicContact NE2-OD2 2.74Å; H311-D475 PolarHBondContact NE2-OD2 3.41Å; L312-D475 HydrophobicContact CD1-CB 4.44Å; M315-D475 HydrophobicContact CE-CB 3.74Å; M315-D475 HydrophobicContact SD-CB 3.43Å; M315-D475 WeakPolarHBondContact SD-CB 3.24Å; D475-I477 VanDerWaalsContact C-N 3.25Å; D475-I477 PolarHBondContact O-N 3.2Å; D475-F478 PolarHBondContact O-N 3.12Å; D475-F478 VanDerWaalsContact O-N 3.13Å; D475-L479 PolarHBondContact O-N 3.24Å
476K97.8Very high98.3Very high90 Ų9025.3 Ų25.339%0.39112%0.124SC..Hα-helixtrans-60.4-33.7172.5-175.8-178.7173.2-1720112.5T474 F478 L479 T480 E524T474-K476 PolarHBondContact O-N 3.4Å; T474-K476 VanDerWaalsContact O-N 3.13Å; K476-F478 VanDerWaalsContact C-N 3.31Å; K476-L479 PolarHBondContact O-N 2.89Å; K476-T480 VanDerWaalsContact O-CB 3.29Å; K476-T480 WeakPolarHBondContact O-CB 3.49Å; K476-T480 PolarHBondContact O-N 2.83Å; K476-T480 PolarHBondContact O-OG1 3.03Å; K476-E524 IonicContact NZ-OE1 2.92Å; K476-E524 PolarHBondContact NZ-OE1 3.37Å; K476-E524 IonicContact NZ-OE2 3.05Å; K476-E524 PolarHBondContact NZ-OE2 3.5Å
477I98.6Very high98.2Very high19 Ų1931.5 Ų31.510%0.09715%0.152CC..Hα-helixtrans-62.2-42.9175.4-62.7-63.4000110.1V461 L470 I473 T474 D475 T480 T481 I517V461-I477 HydrophobicContact CG1-CG2 4.26Å; V461-I477 HydrophobicContact CG2-CG2 4.46Å; L470-I477 HydrophobicContact CD2-CD1 4.09Å; L470-I477 HydrophobicContact CD2-CG1 4.21Å; I473-I477 HydrophobicContact CG2-CB 4.18Å; I473-I477 HydrophobicContact CG2-CG1 4.4Å; I473-I477 HydrophobicContact CG2-CG2 4.21Å; T474-I477 WeakPolarHBondContact O-CB 3.5Å; T474-I477 PolarHBondContact O-N 3.27Å; D475-I477 VanDerWaalsContact C-N 3.25Å; D475-I477 PolarHBondContact O-N 3.2Å; I477-T480 PolarHBondContact O-N 3.5Å; I477-T481 VanDerWaalsContact O-CB 3.28Å; I477-T481 WeakPolarHBondContact O-CB 3.4Å; I477-T481 PolarHBondContact O-N 3.13Å; I477-T481 PolarHBondContact O-OG1 3.37Å; I477-I517 HydrophobicContact CD1-CG1 4.43Å; I477-I517 HydrophobicContact CD1-CG2 4.34Å; I477-I517 HydrophobicContact CG2-CD1 3.77Å; I477-I517 HydrophobicContact CG2-CG1 4.06Å
478F98.8Very high98.2Very high1 Ų134.1 Ų34.10%0.00416%0.164CC..Hα-helixtrans-72.1-37.6-179.8-67.5-73.1000112.4F266 Q271 S275 L312 V457 V461 I473 D475 K476 T481 A482F266-F478 HydrophobicContact CB-CE2 4.22Å; F266-F478 HydrophobicContact CB-CZ 3.77Å; F266-F478 AromaticContact CD2-CE1 3.98Å; F266-F478 HydrophobicContact CD2-CE1 3.98Å; F266-F478 AromaticContact CD2-CZ 3.54Å; F266-F478 HydrophobicContact CD2-CZ 3.54Å; F266-F478 HydrophobicContact CE2-CE1 4.26Å; F266-F478 HydrophobicContact CE2-CZ 4.22Å; F266-F478 AromaticContact CG-CZ 3.77Å; F266-F478 HydrophobicContact CG-CZ 3.77Å; Q271-F478 HydrophobicContact CB-CD1 4.1Å; Q271-F478 HydrophobicContact CB-CD2 3.81Å; Q271-F478 HydrophobicContact CB-CE1 3.91Å; Q271-F478 HydrophobicContact CB-CE2 3.6Å; Q271-F478 HydrophobicContact CB-CG 4.05Å; Q271-F478 HydrophobicContact CB-CZ 3.67Å; Q271-F478 HydrophobicContact CG-CD2 4.37Å; Q271-F478 HydrophobicContact CG-CE2 4.13Å; Q271-F478 VanDerWaalsContact NE2-CE2 3.33Å; Q271-F478 WeakPolarHBondContact O-CD1 3.34Å; S275-F478 WeakPolarHBondContact CB-O 3.29Å; S275-F478 PolarHBondContact OG-O 2.96Å; L312-F478 HydrophobicContact CD1-CB 4.31Å; L312-F478 HydrophobicContact CD2-CB 4.23Å; V457-F478 HydrophobicContact CG1-CD1 4.04Å; V457-F478 HydrophobicContact CG1-CE1 4.24Å; V461-F478 HydrophobicContact CG1-CE1 4.36Å; V461-F478 HydrophobicContact CG1-CZ 4.5Å; V461-F478 HydrophobicContact CG2-CE1 4.36Å; I473-F478 HydrophobicContact CG2-CD2 4.35Å; I473-F478 HydrophobicContact CG2-CE2 3.45Å; I473-F478 VanDerWaalsContact CG2-CE2 3.45Å; I473-F478 HydrophobicContact CG2-CZ 3.76Å; D475-F478 PolarHBondContact O-N 3.12Å; D475-F478 VanDerWaalsContact O-N 3.13Å; K476-F478 VanDerWaalsContact C-N 3.31Å; F478-T481 PolarHBondContact O-N 2.99Å; F478-A482 WeakPolarHBondContact O-CB 3.36Å; F478-A482 PolarHBondContact O-N 3.27Å
479L98.8Very high98.2Very high8 Ų834.2 Ų34.24%0.04216%0.164CC..Hα-helixtrans-64.9-45.2172.9-18057.4000111.5V278 L312 M315 A316 K319 D475 K476 T481 A482 E483V278-L479 HydrophobicContact CG1-CD1 4.17Å; L312-L479 HydrophobicContact CD1-CB 3.96Å; M315-L479 HydrophobicContact CB-CD2 4.44Å; A316-L479 HydrophobicContact CB-CD1 3.68Å; K319-L479 HydrophobicContact CB-CD2 4.44Å; K319-L479 HydrophobicContact CD-CD2 3.94Å; D475-L479 PolarHBondContact O-N 3.24Å; K476-L479 PolarHBondContact O-N 2.89Å; L479-T481 VanDerWaalsContact C-N 3.32Å; L479-T481 PolarHBondContact O-N 3.16Å; L479-A482 WeakPolarHBondContact O-CB 3.2Å; L479-A482 PolarHBondContact O-N 2.75Å; L479-A482 VanDerWaalsContact O-N 3.16Å; L479-E483 WeakPolarHBondContact O-CG 3.37Å; L479-E483 PolarHBondContact O-N 2.82Å
480T98.6Very high98.2Very high10 Ų1036.3 Ų36.36%0.06118%0.178CC..Hα-helixtrans-65.1-38.8177.8-54.30000111.1K476 I477 A482 E483 V484 K516K476-T480 VanDerWaalsContact O-CB 3.29Å; K476-T480 WeakPolarHBondContact O-CB 3.49Å; K476-T480 PolarHBondContact O-N 2.83Å; K476-T480 PolarHBondContact O-OG1 3.03Å; I477-T480 PolarHBondContact O-N 3.5Å; T480-A482 VanDerWaalsContact C-N 3.32Å; T480-A482 PolarHBondContact O-N 2.9Å; T480-E483 WeakPolarHBondContact O-CB 3.18Å; T480-E483 PolarHBondContact O-N 2.81Å; T480-V484 WeakPolarHBondContact O-CG2 3.49Å; T480-V484 PolarHBondContact O-N 2.94Å; T480-K516 HydrophobicContact CG2-CD 4.23Å; T480-K516 HydrophobicContact CG2-CG 3.53Å
481T98.9Very high98.2Very high2 Ų241 Ų411%0.01220%0.204CC..Hα-helixtrans-59.6-43.9172.5-62.40000111.4V457 V461 I477 F478 L479 E483 V484 I485 I513V457-T481 HydrophobicContact CB-CG2 4.44Å; V457-T481 HydrophobicContact CG1-CG2 3.97Å; V457-T481 HydrophobicContact CG2-CG2 4.4Å; V461-T481 HydrophobicContact CG2-CG2 4.07Å; I477-T481 VanDerWaalsContact O-CB 3.28Å; I477-T481 WeakPolarHBondContact O-CB 3.4Å; I477-T481 PolarHBondContact O-N 3.13Å; I477-T481 PolarHBondContact O-OG1 3.37Å; F478-T481 PolarHBondContact O-N 2.99Å; L479-T481 VanDerWaalsContact C-N 3.32Å; L479-T481 PolarHBondContact O-N 3.16Å; T481-E483 VanDerWaalsContact C-N 3.3Å; T481-E483 PolarHBondContact O-N 3.07Å; T481-V484 PolarHBondContact O-N 3.16Å; T481-I485 HydrophobicContact CG2-CD1 3.85Å; T481-I485 HydrophobicContact CG2-CG1 4.47Å; T481-I485 WeakPolarHBondContact O-CG1 3.37Å; T481-I485 PolarHBondContact O-N 2.93Å; T481-I513 HydrophobicContact CG2-CD1 3.77Å; T481-I513 HydrophobicContact CG2-CG1 4Å; T481-I513 HydrophobicContact CG2-CG2 3.82Å
482A98.9Very high98.3Very high0 Ų041.1 Ų41.10%021%0.208CC..Hα-helixtrans-60.1-41.8178.100000112S275 V278 A279 L282 F478 L479 T480 I485 A486S275-A482 WeakPolarHBondContact O-CB 3.26Å; S275-A482 PolarHBondContact OG-N 3.09Å; V278-A482 HydrophobicContact CB-CB 4.09Å; V278-A482 HydrophobicContact CG1-CB 3.91Å; A279-A482 HydrophobicContact CB-CB 4.07Å; A279-A482 WeakPolarHBondContact CB-O 3.17Å; L282-A482 HydrophobicContact CD1-CB 4.43Å; F478-A482 WeakPolarHBondContact O-CB 3.36Å; F478-A482 PolarHBondContact O-N 3.27Å; L479-A482 WeakPolarHBondContact O-CB 3.2Å; L479-A482 PolarHBondContact O-N 2.75Å; L479-A482 VanDerWaalsContact O-N 3.16Å; T480-A482 VanDerWaalsContact C-N 3.32Å; T480-A482 PolarHBondContact O-N 2.9Å; A482-I485 PolarHBondContact O-N 3.43Å; A482-A486 WeakPolarHBondContact O-CB 3.33Å; A482-A486 PolarHBondContact O-N 3.49Å
483E98.8Very high98.4Very high63 Ų6340.3 Ų40.329%0.29420%0.204SC..Hα-helixtrans-63.7-43.3175.4-68.4166.1179.300112.1L282 K319 L479 T480 T481 I485 A486 Q487L282-E483 HydrophobicContact CD1-CG 3.79Å; K319-E483 WeakPolarHBondContact CD-OE1 3.32Å; K319-E483 WeakPolarHBondContact CE-OE1 3.36Å; K319-E483 IonicContact NZ-OE1 2.68Å; K319-E483 PolarHBondContact NZ-OE1 3.11Å; K319-E483 IonicContact NZ-OE2 3.53Å; K319-E483 PolarHBondContact NZ-OE2 3.01Å; L479-E483 WeakPolarHBondContact O-CG 3.37Å; L479-E483 PolarHBondContact O-N 2.82Å; T480-E483 WeakPolarHBondContact O-CB 3.18Å; T480-E483 PolarHBondContact O-N 2.81Å; T481-E483 VanDerWaalsContact C-N 3.3Å; T481-E483 PolarHBondContact O-N 3.07Å; E483-I485 VanDerWaalsContact C-N 3.34Å; E483-I485 PolarHBondContact O-N 3.46Å; E483-A486 PolarHBondContact O-N 2.9Å; E483-Q487 WeakPolarHBondContact O-CB 3.27Å; E483-Q487 PolarHBondContact O-N 3.09Å
484V98.9Very high98.4Very high20 Ų2041 Ų4112%0.12121%0.208CC..Hα-helixtrans-61.5-43.6177.4171.90000111.2T480 T481 Q487 Q488 K512 I513 K516T480-V484 WeakPolarHBondContact O-CG2 3.49Å; T480-V484 PolarHBondContact O-N 2.94Å; T481-V484 PolarHBondContact O-N 3.16Å; V484-Q487 PolarHBondContact O-N 2.68Å; V484-Q488 WeakPolarHBondContact O-CG 3.44Å; V484-Q488 PolarHBondContact O-N 2.91Å; V484-Q488 PolarHBondContact O-NE2 3.46Å; V484-K512 HydrophobicContact CG1-CB 3.95Å; V484-I513 HydrophobicContact CB-CG1 4.2Å; V484-I513 HydrophobicContact CG1-CG1 3.76Å; V484-K516 HydrophobicContact CG2-CB 3.92Å; V484-K516 HydrophobicContact CG2-CG 3.83Å
485I98.8Very high98.4Very high0 Ų044.3 Ų44.30%022%0.218CC..Hα-helixtrans-62.1-50.1177.3-65.3161.5000110.1A279 V457 T481 A482 E483 Q487 Q488 Y500 P501 V509 I513A279-I485 HydrophobicContact CB-CB 3.84Å; A279-I485 HydrophobicContact CB-CD1 4.33Å; A279-I485 HydrophobicContact CB-CG2 3.79Å; V457-I485 HydrophobicContact CG2-CD1 3.78Å; T481-I485 HydrophobicContact CG2-CD1 3.85Å; T481-I485 HydrophobicContact CG2-CG1 4.47Å; T481-I485 WeakPolarHBondContact O-CG1 3.37Å; T481-I485 PolarHBondContact O-N 2.93Å; A482-I485 PolarHBondContact O-N 3.43Å; E483-I485 VanDerWaalsContact C-N 3.34Å; E483-I485 PolarHBondContact O-N 3.46Å; I485-Q487 PolarHBondContact O-N 3.29Å; I485-Q488 PolarHBondContact O-N 2.65Å; I485-Y500 HydrophobicContact CG2-CD1 4.29Å; I485-P501 HydrophobicContact CG2-CG 4.42Å; I485-V509 HydrophobicContact CG1-CG1 4.11Å; I485-I513 HydrophobicContact CD1-CD1 4.23Å; I485-I513 HydrophobicContact CG1-CD1 3.9Å
486A98.7Very high98.4Very high10 Ų1045.2 Ų45.28%0.08322%0.221CC..Hα-helixtrans-60.1-34.2179.100000112.4L282 R286 A482 E483 Q488 V489L282-A486 HydrophobicContact CB-CB 3.77Å; R286-A486 PolarHBondContact NH1-O 3.39Å; A482-A486 WeakPolarHBondContact O-CB 3.33Å; A482-A486 PolarHBondContact O-N 3.49Å; E483-A486 PolarHBondContact O-N 2.9Å; A486-Q488 VanDerWaalsContact C-N 3.27Å; A486-Q488 PolarHBondContact O-N 3.2Å; A486-V489 WeakPolarHBondContact O-CB 3.31Å; A486-V489 PolarHBondContact O-N 2.92Å
487Q98.6Very high98.3Very high146 Ų14641.5 Ų41.568%0.68221%0.209SC*.Hα-helixtrans-68-23.1176.5-172.66048.900113.4E483 V484 I485 V489E483-Q487 WeakPolarHBondContact O-CB 3.27Å; E483-Q487 PolarHBondContact O-N 3.09Å; V484-Q487 PolarHBondContact O-N 2.68Å; I485-Q487 PolarHBondContact O-N 3.29Å; Q487-V489 VanDerWaalsContact C-N 3.29Å
488Q98.4Very high98.3Very high55 Ų5543.3 Ų43.326%0.25721%0.214SC..THydrogen-bonded Turntrans-82.4-5.9175.8-60.1-35.4-7200113V484 I485 A486 S490 P501 V509 K512V484-Q488 WeakPolarHBondContact O-CG 3.44Å; V484-Q488 PolarHBondContact O-N 2.91Å; V484-Q488 PolarHBondContact O-NE2 3.46Å; I485-Q488 PolarHBondContact O-N 2.65Å; A486-Q488 VanDerWaalsContact C-N 3.27Å; A486-Q488 PolarHBondContact O-N 3.2Å; Q488-S490 PolarHBondContact O-N 3.05Å; Q488-P501 HydrophobicContact CB-CB 4.3Å; Q488-P501 HydrophobicContact CB-CG 3.58Å; Q488-V509 HydrophobicContact CB-CG2 4.44Å; Q488-V509 HydrophobicContact CG-CG2 4.25Å; Q488-K512 HydrophobicContact CG-CD 4.07Å
489V98.4Very high98.3Very high2 Ų243.3 Ų43.31%0.01221%0.214CC..  trans-82.4113.1176-172.20000108.9A283 R286 A486 Q487 H493 L494 P501A283-V489 HydrophobicContact CB-CG2 4.35Å; R286-V489 VanDerWaalsContact CZ-O 3.29Å; R286-V489 PolarHBondContact NH1-O 3.29Å; R286-V489 PolarHBondContact NH2-O 2.88Å; A486-V489 WeakPolarHBondContact O-CB 3.31Å; A486-V489 PolarHBondContact O-N 2.92Å; Q487-V489 VanDerWaalsContact C-N 3.29Å; V489-H493 HydrophobicContact CG1-CB 3.7Å; V489-L494 HydrophobicContact CG1-CD2 3.59Å; V489-L494 HydrophobicContact CG1-CG 4Å; V489-P501 HydrophobicContact CG2-CG 4.22Å
490S98.3Very high98.2Very high48 Ų4843.1 Ų43.134%0.33621%0.213SC..  trans-72.2159.5175.871.50000111.6Q488 K492 H493 L494Q488-S490 PolarHBondContact O-N 3.05Å; S490-K492 PolarHBondContact O-N 3.05Å; S490-H493 PolarHBondContact N-ND1 3.42Å; S490-H493 WeakPolarHBondContact O-CB 3.38Å; S490-H493 PolarHBondContact O-N 2.92Å; S490-H493 PolarHBondContact OG-CD2 3.35Å; S490-H493 PolarHBondContact OG-N 3.24Å; S490-H493 VanDerWaalsContact OG-N 3.12Å; S490-H493 PolarHBondContact OG-ND1 3.09Å; S490-L494 PolarHBondContact O-N 3.07Å
491D98.3Very high98.2Very high105 Ų10542.8 Ų42.856%0.56121%0.211SC*.Hα-helixtrans-61.1-34.2174.5-64-33.8000111.7R286 H493 L494 E495R286-D491 IonicContact CZ-OD1 2.85Å; R286-D491 IonicContact NE-OD1 3.78Å; R286-D491 IonicContact NH2-OD1 3.83Å; R286-D491 PolarHBondContact NH2-OD1 3.04Å; D491-H493 VanDerWaalsContact C-N 3.31Å; D491-H493 PolarHBondContact O-N 3.37Å; D491-L494 WeakPolarHBondContact O-CB 3.13Å; D491-L494 PolarHBondContact O-N 3.35Å; D491-L494 VanDerWaalsContact O-N 3.07Å; D491-E495 WeakPolarHBondContact O-CG 3.48Å; D491-E495 PolarHBondContact O-N 3Å
492K97.8Very high98Very high134 Ų13444.2 Ų44.258%0.58322%0.221SC*.Hα-helixtrans-58.2-41.6171.2-179.6-179.4173.5-177.10112.3S490 L494 E495 E496S490-K492 PolarHBondContact O-N 3.05Å; K492-L494 VanDerWaalsContact C-N 3.29Å; K492-L494 PolarHBondContact O-N 2.92Å; K492-E495 PolarHBondContact O-N 3.12Å; K492-E496 WeakPolarHBondContact CE-OE1 3.36Å; K492-E496 WeakPolarHBondContact O-CG 3.48Å; K492-E496 PolarHBondContact O-N 2.94Å
493H98.1Very high97.6Very high38 Ų3844.8 Ų44.818%0.17622%0.224CC..Hα-helixtrans-61.7-40.5175.4-63.7159.6000111.1V489 S490 D491 E496 G497 R498 P502V489-H493 HydrophobicContact CG1-CB 3.7Å; S490-H493 PolarHBondContact N-ND1 3.42Å; S490-H493 WeakPolarHBondContact O-CB 3.38Å; S490-H493 PolarHBondContact O-N 2.92Å; S490-H493 PolarHBondContact OG-CD2 3.35Å; S490-H493 PolarHBondContact OG-N 3.24Å; S490-H493 VanDerWaalsContact OG-N 3.12Å; S490-H493 PolarHBondContact OG-ND1 3.09Å; D491-H493 VanDerWaalsContact C-N 3.31Å; D491-H493 PolarHBondContact O-N 3.37Å; H493-E496 CarbonylContact O-C 3.57Å; H493-E496 WeakPolarHBondContact O-CB 3.32Å; H493-E496 PolarHBondContact O-N 2.91Å; H493-G497 PolarHBondContact O-N 3.27Å; H493-R498 HydrophobicContact CB-CB 4.07Å; H493-R498 WeakPolarHBondContact O-CB 3.34Å; H493-R498 PolarHBondContact O-N 3.33Å; H493-P502 VanDerWaalsContact CE1-CD 3.45Å; H493-P502 WeakPolarHBondContact CE1-CD 3.2Å
494L98.1Very high97.4Very high17 Ų1747.3 Ų47.39%0.08924%0.239CC..Hα-helixtrans-66.4-39.4177.4-59.8179.2000112.3A283 R286 I287 V489 S490 D491 K492 E496 G497 L499A283-L494 HydrophobicContact CB-CD2 4.28Å; R286-L494 HydrophobicContact CB-CD1 3.62Å; I287-L494 HydrophobicContact CD1-CB 4.23Å; I287-L494 HydrophobicContact CD1-CD2 4.06Å; I287-L494 HydrophobicContact CG1-CB 4.01Å; I287-L494 HydrophobicContact CG1-CD1 4.32Å; I287-L494 HydrophobicContact CG1-CD2 4.09Å; I287-L494 HydrophobicContact CG1-CG 4.37Å; V489-L494 HydrophobicContact CG1-CD2 3.59Å; V489-L494 HydrophobicContact CG1-CG 4Å; S490-L494 PolarHBondContact O-N 3.07Å; D491-L494 WeakPolarHBondContact O-CB 3.13Å; D491-L494 PolarHBondContact O-N 3.35Å; D491-L494 VanDerWaalsContact O-N 3.07Å; K492-L494 VanDerWaalsContact C-N 3.29Å; K492-L494 PolarHBondContact O-N 2.92Å; L494-E496 VanDerWaalsContact C-N 3.25Å; L494-E496 PolarHBondContact O-N 3.3Å; L494-G497 WeakPolarHBondContact O-CA 3.5Å; L494-G497 PolarHBondContact O-N 2.85Å; L494-L499 HydrophobicContact CD2-CD2 4.41Å
495E97.2Very high97.3Very high139 Ų13948.8 Ų48.865%0.6525%0.248SC*.Hα-helixtrans-62.2-33.5174.1-70.9170.9-178.500112.3Q445 D491 K492 G497Q445-E495 PolarHBondContact NE2-O 3.44Å; D491-E495 WeakPolarHBondContact O-CG 3.48Å; D491-E495 PolarHBondContact O-N 3Å; K492-E495 PolarHBondContact O-N 3.12Å; E495-G497 PolarHBondContact O-N 3.17Å
496E97.1Very high97.3Very high42 Ų4248.9 Ų48.920%0.19625%0.249CC..THydrogen-bonded Turntrans-78.1-1.3172-72.7177.2-162.400113.3L447 Y448 K492 H493 L494 R498L447-E496 CarbonylContact C-O 3.6Å; L447-E496 WeakPolarHBondContact CA-O 3.38Å; Y448-E496 HydrophobicContact CD2-CB 3.96Å; Y448-E496 HydrophobicContact CD2-CG 4.26Å; Y448-E496 HydrophobicContact CE2-CG 4.43Å; Y448-E496 PolarHBondContact N-O 2.99Å; K492-E496 WeakPolarHBondContact CE-OE1 3.36Å; K492-E496 WeakPolarHBondContact O-CG 3.48Å; K492-E496 PolarHBondContact O-N 2.94Å; H493-E496 CarbonylContact O-C 3.57Å; H493-E496 WeakPolarHBondContact O-CB 3.32Å; H493-E496 PolarHBondContact O-N 2.91Å; L494-E496 VanDerWaalsContact C-N 3.25Å; L494-E496 PolarHBondContact O-N 3.3Å; E496-R498 HydrophobicContact CB-CG 4.28Å; E496-R498 IonicContact OE2-CZ 3.53Å; E496-R498 IonicContact OE2-NE 3.96Å; E496-R498 PolarHBondContact OE2-NE 3.39Å; E496-R498 IonicContact OE2-NH2 2.7Å; E496-R498 PolarHBondContact OE2-NH2 3.2Å
497G96.7Very high97.2Very high12 Ų1251.7 Ų51.712%0.12426%0.257CS..THydrogen-bonded Turntrans79.411-178.900000115.2H493 L494 E495H493-G497 PolarHBondContact O-N 3.27Å; L494-G497 WeakPolarHBondContact O-CA 3.5Å; L494-G497 PolarHBondContact O-N 2.85Å; E495-G497 PolarHBondContact O-N 3.17Å
498R97.7Very high97.2Very high58 Ų5847.9 Ų47.922%0.21924%0.242CC..  trans-84.6130.1178.4-54.6175-168.4-88.90.6110.5Y448 H493 E496Y448-R498 VanDerWaalsContact CG-CZ 3.45Å; Y448-R498 VanDerWaalsContact O-CG 3.29Å; Y448-R498 WeakPolarHBondContact O-CG 3.27Å; H493-R498 HydrophobicContact CB-CB 4.07Å; H493-R498 WeakPolarHBondContact O-CB 3.34Å; H493-R498 PolarHBondContact O-N 3.33Å; E496-R498 HydrophobicContact CB-CG 4.28Å; E496-R498 IonicContact OE2-CZ 3.53Å; E496-R498 IonicContact OE2-NE 3.96Å; E496-R498 PolarHBondContact OE2-NE 3.39Å; E496-R498 IonicContact OE2-NH2 2.7Å; E496-R498 PolarHBondContact OE2-NH2 3.2Å
499L98.4Very high97.2Very high0 Ų045.3 Ų45.30%023%0.23CC..SBendtrans-98.6-5.1173.5-68.5-176.5000114.6A283 A284 I287 F404 I429 A431 L494A283-L499 HydrophobicContact CB-CB 4.39Å; A283-L499 HydrophobicContact CB-CD2 4.03Å; A283-L499 VanDerWaalsContact CB-O 3.31Å; A283-L499 WeakPolarHBondContact CB-O 3.29Å; A284-L499 HydrophobicContact CB-CD1 4.31Å; A284-L499 HydrophobicContact CB-CD2 3.94Å; I287-L499 HydrophobicContact CD1-CD2 3.99Å; F404-L499 HydrophobicContact CD1-CD1 4.49Å; F404-L499 HydrophobicContact CE1-CD1 3.34Å; F404-L499 HydrophobicContact CZ-CD1 3.64Å; I429-L499 HydrophobicContact CG2-CD1 3.62Å; I429-L499 HydrophobicContact CG2-CD2 3.64Å; I429-L499 HydrophobicContact CG2-CG 3.91Å; A431-L499 HydrophobicContact CB-CD1 4.08Å; L494-L499 HydrophobicContact CD2-CD2 4.41Å
500Y98.3Very high97.3Very high4 Ų445.2 Ų45.22%0.01623%0.229CC..SBendtrans-131.3155.8-178-57.9-78.1000109.7V276 A279 G280 A431 Q451 G452 Y456 I485V276-Y500 HydrophobicContact CG2-CD1 4.22Å; V276-Y500 HydrophobicContact CG2-CE1 3.6Å; V276-Y500 VanDerWaalsContact O-CE1 3.3Å; V276-Y500 WeakPolarHBondContact O-CE1 3.29Å; V276-Y500 PolarHBondContact O-OH 3.36Å; A279-Y500 HydrophobicContact CB-CE1 4.32Å; G280-Y500 WeakPolarHBondContact CA-OH 3.13Å; A431-Y500 HydrophobicContact CB-CE2 3.82Å; Q451-Y500 WeakPolarHBondContact O-CD2 3.04Å; G452-Y500 VanDerWaalsContact CA-CE2 3.49Å; G452-Y500 VanDerWaalsContact CA-CZ 3.47Å; Y456-Y500 HydrophobicContact CE2-CG 4.44Å; I485-Y500 HydrophobicContact CG2-CD1 4.29Å
501P97.2Very high97.3Very high4 Ų443 Ų433%0.02621%0.214CC..  trans-58.7156.9171.3-2235.3000111Y456 I485 Q488 V489 V509Y456-P501 HydrophobicContact CE1-CB 4.38Å; Y456-P501 PolarHBondContact OH-O 2.69Å; I485-P501 HydrophobicContact CG2-CG 4.42Å; Q488-P501 HydrophobicContact CB-CB 4.3Å; Q488-P501 HydrophobicContact CB-CG 3.58Å; V489-P501 HydrophobicContact CG2-CG 4.22Å; P501-V509 HydrophobicContact CB-CG2 3.97Å; P501-V509 HydrophobicContact CG-CG2 4.02Å
502P95.1Very high97.3Very high32 Ų3241.2 Ų41.221%0.20820%0.201CC..  trans-61.2141.4172.2-24.435.3000112.1H493 N504 T505H493-P502 VanDerWaalsContact CE1-CD 3.45Å; H493-P502 WeakPolarHBondContact CE1-CD 3.2Å; P502-N504 VanDerWaalsContact C-N 3.25Å; P502-N504 WeakPolarHBondContact CB-OD1 3.44Å; P502-N504 PolarHBondContact O-N 3.21Å; P502-T505 HydrophobicContact CB-CG2 4.48Å; P502-T505 WeakPolarHBondContact O-CB 3.5Å; P502-T505 PolarHBondContact O-N 3.03Å; P502-T505 PolarHBondContact O-OG1 3.44Å
503L91.6Very high97.4Very high12 Ų1234.9 Ų34.96%0.06317%0.173CC..G310 helixtrans-59.5-33.1-176.4-81.6171.2000113.2V94 E95 M98 Y456 T505 I506V94-L503 HydrophobicContact CG1-CB 4.49Å; V94-L503 VanDerWaalsContact CG1-O 3.31Å; V94-L503 WeakPolarHBondContact CG1-O 3.37Å; E95-L503 HydrophobicContact CB-CB 4.46Å; E95-L503 HydrophobicContact CG-CD1 4.17Å; M98-L503 HydrophobicContact CE-CD1 3.72Å; M98-L503 HydrophobicContact CE-CD2 3.75Å; M98-L503 HydrophobicContact CE-CG 4.41Å; M98-L503 HydrophobicContact SD-CD2 4.3Å; Y456-L503 HydrophobicContact CE2-CD2 4.07Å; Y456-L503 VanDerWaalsContact OH-CD2 3.26Å; Y456-L503 WeakPolarHBondContact OH-CD2 3.46Å; Y456-L503 WeakPolarHBondContact OH-CG 3.36Å; L503-T505 PolarHBondContact O-N 3.4Å; L503-T505 VanDerWaalsContact O-N 3.08Å; L503-I506 WeakPolarHBondContact O-CB 3.27Å; L503-I506 VanDerWaalsContact O-CG2 3.24Å; L503-I506 WeakPolarHBondContact O-CG2 3.43Å; L503-I506 PolarHBondContact O-N 2.65Å
504N94.1Very high97.4Very high115 Ų11533.1 Ų33.162%0.61517%0.165SC*.G310 helixtrans-61.8-16.3175.9658.4000113.9P502P502-N504 VanDerWaalsContact C-N 3.25Å; P502-N504 WeakPolarHBondContact CB-OD1 3.44Å; P502-N504 PolarHBondContact O-N 3.21Å
505T97Very high97.5Very high51 Ų5133.9 Ų33.931%0.31317%0.168SC..G310 helixtrans-92.10.4175.269.60000113.8P502 L503 R507 D508 V509P502-T505 HydrophobicContact CB-CG2 4.48Å; P502-T505 WeakPolarHBondContact O-CB 3.5Å; P502-T505 PolarHBondContact O-N 3.03Å; P502-T505 PolarHBondContact O-OG1 3.44Å; L503-T505 PolarHBondContact O-N 3.4Å; L503-T505 VanDerWaalsContact O-N 3.08Å; T505-R507 PolarHBondContact O-N 3.39Å; T505-D508 WeakPolarHBondContact O-CB 3.43Å; T505-D508 PolarHBondContact O-N 3.42Å; T505-V509 PolarHBondContact O-N 2.76Å
506I97.5Very high97.5Very high3 Ų330.9 Ų30.92%0.01515%0.153CC..Hα-helixtrans-55.4-31.9-170-163.766.6000114.5V94 C180 S455 Y456 L503 S510V94-I506 HydrophobicContact CG1-CG2 4.34Å; V94-I506 HydrophobicContact CG2-CG2 4.23Å; C180-I506 HydrophobicContact CB-CG1 3.86Å; C180-I506 HydrophobicContact CB-CG2 3.98Å; S455-I506 WeakPolarHBondContact O-CD1 3.45Å; Y456-I506 HydrophobicContact CD1-CD1 3.13Å; Y456-I506 HydrophobicContact CE1-CD1 3.4Å; Y456-I506 HydrophobicContact CG-CD1 3.76Å; L503-I506 WeakPolarHBondContact O-CB 3.27Å; L503-I506 VanDerWaalsContact O-CG2 3.24Å; L503-I506 WeakPolarHBondContact O-CG2 3.43Å; L503-I506 PolarHBondContact O-N 2.65Å; I506-S510 WeakPolarHBondContact O-CB 3.45Å; I506-S510 PolarHBondContact O-N 3.27Å; I506-S510 PolarHBondContact O-OG 3.22Å
507R98.3Very high97.6Very high68 Ų6829 Ų2926%0.25714%0.144SC..Hα-helixtrans-69.1-37.6176.3-70.3-174.468.885.5-4.5112.7T178 A179 C180 T505 L511 Y545T178-R507 PolarHBondContact O-NH1 2.85Å; A179-R507 VanDerWaalsContact O-CD 3.29Å; A179-R507 WeakPolarHBondContact O-CD 3.45Å; A179-R507 VanDerWaalsContact O-CG 3.26Å; A179-R507 WeakPolarHBondContact O-CG 3.35Å; A179-R507 PolarHBondContact O-NH1 3.13Å; C180-R507 VanDerWaalsContact O-CA 3.29Å; C180-R507 WeakPolarHBondContact O-CA 3.4Å; C180-R507 WeakPolarHBondContact O-CG 3.42Å; T505-R507 PolarHBondContact O-N 3.39Å; R507-L511 PolarHBondContact O-N 3.07Å; R507-Y545 PolarHBondContact NH2-O 2.97Å; R507-Y545 VanDerWaalsContact NH2-O 3.12Å
508D98.5Very high97.7Very high67 Ų6728.4 Ų28.436%0.35814%0.138SC..Hα-helixtrans-72.5-40.1175.6-172.164.8000111T505 S510 L511 K512T505-D508 WeakPolarHBondContact O-CB 3.43Å; T505-D508 PolarHBondContact O-N 3.42Å; D508-S510 VanDerWaalsContact C-N 3.34Å; D508-S510 PolarHBondContact O-N 3.41Å; D508-L511 WeakPolarHBondContact O-CB 3.09Å; D508-L511 PolarHBondContact O-N 2.73Å; D508-K512 WeakPolarHBondContact O-CG 3.22Å; D508-K512 PolarHBondContact O-N 3.32Å; D508-K512 WeakPolarHBondContact OD2-CE 3.35Å
509V98.7Very high97.8Very high1 Ų130.2 Ų30.21%0.00615%0.147CC..Hα-helixtrans-57.2-48.4171.5177.80000110.4Y456 I485 Q488 P501 T505 L511 K512 I513Y456-V509 HydrophobicContact CD1-CG1 4.41Å; I485-V509 HydrophobicContact CG1-CG1 4.11Å; Q488-V509 HydrophobicContact CB-CG2 4.44Å; Q488-V509 HydrophobicContact CG-CG2 4.25Å; P501-V509 HydrophobicContact CB-CG2 3.97Å; P501-V509 HydrophobicContact CG-CG2 4.02Å; T505-V509 PolarHBondContact O-N 2.76Å; V509-L511 VanDerWaalsContact C-N 3.32Å; V509-L511 PolarHBondContact O-N 3.42Å; V509-K512 PolarHBondContact O-N 2.87Å; V509-I513 HydrophobicContact CG1-CD1 3.84Å; V509-I513 HydrophobicContact CG1-CG1 4.48Å; V509-I513 VanDerWaalsContact O-CG1 3.31Å; V509-I513 WeakPolarHBondContact O-CG1 3.34Å; V509-I513 PolarHBondContact O-N 3.48Å
510S98.9Very high97.8Very high0 Ų031 Ų310%015%0.152CC..Hα-helixtrans-61.1-39.8178.7-62.20000112.6C180 G460 I506 D508 I513 A514C180-S510 WeakPolarHBondContact O-CB 3.44Å; C180-S510 PolarHBondContact O-OG 3.31Å; C180-S510 VanDerWaalsContact O-OG 3.11Å; G460-S510 WeakPolarHBondContact CA-O 3.38Å; I506-S510 WeakPolarHBondContact O-CB 3.45Å; I506-S510 PolarHBondContact O-N 3.27Å; I506-S510 PolarHBondContact O-OG 3.22Å; D508-S510 VanDerWaalsContact C-N 3.34Å; D508-S510 PolarHBondContact O-N 3.41Å; S510-I513 PolarHBondContact O-N 2.89Å; S510-A514 WeakPolarHBondContact O-CB 3.31Å; S510-A514 PolarHBondContact O-N 2.66Å
511L98.8Very high97.8Very high2 Ų231 Ų311%0.0115%0.152CC..Hα-helixtrans-61.3-47.6173.9170.265.5000111.7R507 D508 V509 I513 A514 E515 E537 V540 R541 M544R507-L511 PolarHBondContact O-N 3.07Å; D508-L511 WeakPolarHBondContact O-CB 3.09Å; D508-L511 PolarHBondContact O-N 2.73Å; V509-L511 VanDerWaalsContact C-N 3.32Å; V509-L511 PolarHBondContact O-N 3.42Å; L511-I513 VanDerWaalsContact C-N 3.32Å; L511-I513 PolarHBondContact O-N 3.46Å; L511-A514 PolarHBondContact O-N 3Å; L511-E515 WeakPolarHBondContact O-CB 3.29Å; L511-E515 PolarHBondContact O-N 2.91Å; L511-E537 HydrophobicContact CD1-CG 4.47Å; L511-E537 HydrophobicContact CD2-CG 4.38Å; L511-V540 HydrophobicContact CD1-CB 3.87Å; L511-V540 HydrophobicContact CD1-CG1 3.49Å; L511-V540 VanDerWaalsContact CD1-CG1 3.49Å; L511-R541 HydrophobicContact CD1-CG 3.88Å; L511-R541 HydrophobicContact CD2-CG 3.89Å; L511-M544 HydrophobicContact CB-SD 4.3Å; L511-M544 HydrophobicContact CD1-SD 4.05Å
512K98.9Very high97.9Very high67 Ų6731.3 Ų31.329%0.29115%0.153SC..Hα-helixtrans-64.7-37.2-179.5-70.3174.3-173.5-78.10112.2V484 Q488 D508 V509 K516V484-K512 HydrophobicContact CG1-CB 3.95Å; Q488-K512 HydrophobicContact CG-CD 4.07Å; D508-K512 WeakPolarHBondContact O-CG 3.22Å; D508-K512 PolarHBondContact O-N 3.32Å; D508-K512 WeakPolarHBondContact OD2-CE 3.35Å; V509-K512 PolarHBondContact O-N 2.87Å; K512-K516 WeakPolarHBondContact O-CB 3.37Å; K512-K516 PolarHBondContact O-N 3.3Å
513I98.9Very high98Very high1 Ų137 Ų371%0.00518%0.177CC..Hα-helixtrans-61.1-52.7172.6-68163.9000109.6Y456 V461 T481 V484 I485 V509 S510 L511 E515 K516 I517Y456-I513 WeakPolarHBondContact O-CD1 3.47Å; V461-I513 HydrophobicContact CG2-CG2 4.27Å; T481-I513 HydrophobicContact CG2-CD1 3.77Å; T481-I513 HydrophobicContact CG2-CG1 4Å; T481-I513 HydrophobicContact CG2-CG2 3.82Å; V484-I513 HydrophobicContact CB-CG1 4.2Å; V484-I513 HydrophobicContact CG1-CG1 3.76Å; I485-I513 HydrophobicContact CD1-CD1 4.23Å; I485-I513 HydrophobicContact CG1-CD1 3.9Å; V509-I513 HydrophobicContact CG1-CD1 3.84Å; V509-I513 HydrophobicContact CG1-CG1 4.48Å; V509-I513 VanDerWaalsContact O-CG1 3.31Å; V509-I513 WeakPolarHBondContact O-CG1 3.34Å; V509-I513 PolarHBondContact O-N 3.48Å; S510-I513 PolarHBondContact O-N 2.89Å; L511-I513 VanDerWaalsContact C-N 3.32Å; L511-I513 PolarHBondContact O-N 3.46Å; I513-E515 PolarHBondContact O-N 3.37Å; I513-K516 PolarHBondContact O-N 3.12Å; I513-I517 HydrophobicContact CG2-CD1 3.8Å; I513-I517 WeakPolarHBondContact O-CG1 3.38Å; I513-I517 PolarHBondContact O-N 2.83Å
514A98.9Very high98.3Very high0 Ų040.7 Ų40.70%019%0.194CC..Hα-helixtrans-60-45.2-179.900000111.8L463 S510 L511 K516 I517 V518 V540L463-A514 HydrophobicContact CB-CB 3.96Å; L463-A514 HydrophobicContact CD2-CB 3.58Å; L463-A514 HydrophobicContact CG-CB 3.72Å; S510-A514 WeakPolarHBondContact O-CB 3.31Å; S510-A514 PolarHBondContact O-N 2.66Å; L511-A514 PolarHBondContact O-N 3Å; A514-K516 VanDerWaalsContact C-N 3.3Å; A514-K516 PolarHBondContact O-N 3.43Å; A514-I517 PolarHBondContact O-N 2.8Å; A514-V518 VanDerWaalsContact O-CG2 3.27Å; A514-V518 WeakPolarHBondContact O-CG2 3.48Å; A514-V518 PolarHBondContact O-N 3.42Å; A514-V540 HydrophobicContact CB-CG1 3.85Å; A514-V540 HydrophobicContact CB-CG2 4.48Å
515E98.8Very high98.5Very high34 Ų3443.6 Ų43.616%0.15920%0.201CC..Hα-helixtrans-56.5-44.6176.1-174.1-168.8170.200111.5L511 I513 V518 K519 K536 E537L511-E515 WeakPolarHBondContact O-CB 3.29Å; L511-E515 PolarHBondContact O-N 2.91Å; I513-E515 PolarHBondContact O-N 3.37Å; E515-V518 PolarHBondContact O-N 2.88Å; E515-K519 HydrophobicContact CG-CD 4.36Å; E515-K519 WeakPolarHBondContact O-CB 3.41Å; E515-K519 WeakPolarHBondContact O-CG 3.49Å; E515-K519 PolarHBondContact O-N 3.07Å; E515-K519 WeakPolarHBondContact OE1-CE 3.37Å; E515-K519 IonicContact OE1-NZ 2.65Å; E515-K519 PolarHBondContact OE1-NZ 3.38Å; E515-K536 HydrophobicContact CG-CB 4.48Å; E515-E537 HydrophobicContact CG-CB 4.27Å
516K98.8Very high98.5Very high76 Ų7644.2 Ų44.233%0.3321%0.205SC..Hα-helixtrans-64.2-45178-177.454.5173.9154.20111.7T480 V484 K512 I513 A514 V518 K519 D520T480-K516 HydrophobicContact CG2-CD 4.23Å; T480-K516 HydrophobicContact CG2-CG 3.53Å; V484-K516 HydrophobicContact CG2-CB 3.92Å; V484-K516 HydrophobicContact CG2-CG 3.83Å; K512-K516 WeakPolarHBondContact O-CB 3.37Å; K512-K516 PolarHBondContact O-N 3.3Å; I513-K516 PolarHBondContact O-N 3.12Å; A514-K516 VanDerWaalsContact C-N 3.3Å; A514-K516 PolarHBondContact O-N 3.43Å; K516-V518 PolarHBondContact O-N 2.85Å; K516-K519 PolarHBondContact O-N 2.89Å; K516-D520 WeakPolarHBondContact CE-OD2 3.49Å; K516-D520 VanDerWaalsContact NZ-CG 3.29Å; K516-D520 IonicContact NZ-OD1 3.63Å; K516-D520 PolarHBondContact NZ-OD1 3.34Å; K516-D520 IonicContact NZ-OD2 3.73Å; K516-D520 PolarHBondContact NZ-OD2 3.44Å; K516-D520 WeakPolarHBondContact O-CB 3.42Å; K516-D520 VanDerWaalsContact O-CG 3.29Å; K516-D520 PolarHBondContact O-N 3.01Å
517I98.9Very high98.6Very high2 Ų244.3 Ų44.31%0.0121%0.206CC..Hα-helixtrans-59.7-47.3175.3-67.7169.6000110.7V461 I477 I513 A514 K519 D520 A521V461-I517 HydrophobicContact CB-CD1 4.37Å; V461-I517 HydrophobicContact CG2-CD1 4.23Å; I477-I517 HydrophobicContact CD1-CG1 4.43Å; I477-I517 HydrophobicContact CD1-CG2 4.34Å; I477-I517 HydrophobicContact CG2-CD1 3.77Å; I477-I517 HydrophobicContact CG2-CG1 4.06Å; I513-I517 HydrophobicContact CG2-CD1 3.8Å; I513-I517 WeakPolarHBondContact O-CG1 3.38Å; I513-I517 PolarHBondContact O-N 2.83Å; A514-I517 PolarHBondContact O-N 2.8Å; I517-K519 PolarHBondContact O-N 3.15Å; I517-D520 PolarHBondContact O-N 2.77Å; I517-A521 WeakPolarHBondContact O-CB 3.39Å; I517-A521 PolarHBondContact O-N 3.43Å
518V98.9Very high98.6Very high0 Ų043.6 Ų43.60%021%0.209CC..Hα-helixtrans-60.7-46.3179.2174.60000110.8A467 C468 A514 E515 K516 A521 Y522 K536 F539 V540A467-V518 HydrophobicContact CB-CG2 4.19Å; C468-V518 HydrophobicContact CB-CB 4.41Å; C468-V518 HydrophobicContact CB-CG1 4.28Å; C468-V518 HydrophobicContact CB-CG2 3.97Å; A514-V518 VanDerWaalsContact O-CG2 3.27Å; A514-V518 WeakPolarHBondContact O-CG2 3.48Å; A514-V518 PolarHBondContact O-N 3.42Å; E515-V518 PolarHBondContact O-N 2.88Å; K516-V518 PolarHBondContact O-N 2.85Å; V518-A521 PolarHBondContact O-N 3.4Å; V518-Y522 HydrophobicContact CG1-CD2 3.84Å; V518-Y522 HydrophobicContact CG1-CE2 3.6Å; V518-Y522 WeakPolarHBondContact O-CD2 3.39Å; V518-Y522 PolarHBondContact O-N 3.2Å; V518-K536 HydrophobicContact CG1-CB 4.25Å; V518-K536 HydrophobicContact CG1-CG 3.79Å; V518-F539 HydrophobicContact CG1-CD1 4.41Å; V518-F539 HydrophobicContact CG1-CE1 4.48Å; V518-V540 HydrophobicContact CG2-CG2 3.83Å
519K98.8Very high98.6Very high95 Ų9542.8 Ų42.841%0.41321%0.207SC..Hα-helixtrans-58.1-51.7177.4-76.4175.1-178.1171.90111.7E515 K516 I517 A521 Y522 Q523 K536E515-K519 HydrophobicContact CG-CD 4.36Å; E515-K519 WeakPolarHBondContact O-CB 3.41Å; E515-K519 WeakPolarHBondContact O-CG 3.49Å; E515-K519 PolarHBondContact O-N 3.07Å; E515-K519 WeakPolarHBondContact OE1-CE 3.37Å; E515-K519 IonicContact OE1-NZ 2.65Å; E515-K519 PolarHBondContact OE1-NZ 3.38Å; K516-K519 PolarHBondContact O-N 2.89Å; I517-K519 PolarHBondContact O-N 3.15Å; K519-A521 VanDerWaalsContact C-N 3.31Å; K519-A521 PolarHBondContact O-N 2.92Å; K519-Y522 PolarHBondContact O-N 3.25Å; K519-Q523 PolarHBondContact O-N 2.94Å; K519-Q523 VanDerWaalsContact O-N 3.07Å; K519-K536 HydrophobicContact CG-CB 4.14Å; K519-K536 HydrophobicContact CG-CG 4.03Å
520D98.5Very high98.5Very high17 Ų1749.6 Ų49.69%0.09123%0.233CC..Hα-helixtrans-67.2-35.9-176.4-66.1-7.6000111K516 I517 Y522 Q523 E524K516-D520 WeakPolarHBondContact CE-OD2 3.49Å; K516-D520 VanDerWaalsContact NZ-CG 3.29Å; K516-D520 IonicContact NZ-OD1 3.63Å; K516-D520 PolarHBondContact NZ-OD1 3.34Å; K516-D520 IonicContact NZ-OD2 3.73Å; K516-D520 PolarHBondContact NZ-OD2 3.44Å; K516-D520 WeakPolarHBondContact O-CB 3.42Å; K516-D520 VanDerWaalsContact O-CG 3.29Å; K516-D520 PolarHBondContact O-N 3.01Å; I517-D520 PolarHBondContact O-N 2.77Å; D520-Y522 PolarHBondContact O-N 3.24Å; D520-Q523 PolarHBondContact O-N 3.07Å; D520-E524 WeakPolarHBondContact O-CB 3.32Å; D520-E524 WeakPolarHBondContact O-CG 3.46Å; D520-E524 PolarHBondContact O-N 3.25Å
521A98.6Very high98.5Very high3 Ų355.1 Ų55.13%0.02527%0.269CS..Hα-helixtrans-64.3-39.6178.200000113.2C468 L470 I517 V518 K519 K525 T526 A527C468-A521 HydrophobicContact CB-CB 4.43Å; L470-A521 HydrophobicContact CD1-CB 3.84Å; I517-A521 WeakPolarHBondContact O-CB 3.39Å; I517-A521 PolarHBondContact O-N 3.43Å; V518-A521 PolarHBondContact O-N 3.4Å; K519-A521 VanDerWaalsContact C-N 3.31Å; K519-A521 PolarHBondContact O-N 2.92Å; A521-K525 PolarHBondContact O-N 2.71Å; A521-K525 VanDerWaalsContact O-N 3.1Å; A521-T526 WeakPolarHBondContact CA-OG1 3.36Å; A521-T526 PolarHBondContact O-N 2.75Å; A521-T526 PolarHBondContact O-OG1 3.13Å; A521-A527 HydrophobicContact CB-CB 3.96Å; A521-A527 PolarHBondContact O-N 3.15Å; A521-A527 VanDerWaalsContact O-N 3.17Å
522Y98.6Very high98.5Very high12 Ų1259.5 Ų59.55%0.04729%0.29CS..Hα-helixtrans-71.9-41.8173.5-76.2-69.6000111.9C468 V518 K519 D520 E524 K525 A527 V529 Y530 E532 P533C468-Y522 HydrophobicContact CB-CE2 4.45Å; V518-Y522 HydrophobicContact CG1-CD2 3.84Å; V518-Y522 HydrophobicContact CG1-CE2 3.6Å; V518-Y522 WeakPolarHBondContact O-CD2 3.39Å; V518-Y522 PolarHBondContact O-N 3.2Å; K519-Y522 PolarHBondContact O-N 3.25Å; D520-Y522 PolarHBondContact O-N 3.24Å; Y522-E524 VanDerWaalsContact C-N 3.27Å; Y522-E524 PolarHBondContact O-N 3.32Å; Y522-K525 PolarHBondContact O-N 3.39Å; Y522-K525 VanDerWaalsContact O-N 3.14Å; Y522-A527 HydrophobicContact CD1-CB 3.74Å; Y522-A527 HydrophobicContact CD2-CB 4.38Å; Y522-A527 HydrophobicContact CE1-CB 3.7Å; Y522-A527 HydrophobicContact CE2-CB 4.35Å; Y522-A527 HydrophobicContact CG-CB 4.07Å; Y522-V529 WeakPolarHBondContact CE1-O 3.12Å; Y522-V529 PolarHBondContact OH-O 3.19Å; Y522-Y530 HydrophobicContact CE1-CE1 4.31Å; Y522-E532 HydrophobicContact CD1-CB 3.77Å; Y522-E532 HydrophobicContact CD1-CG 3.55Å; Y522-E532 HydrophobicContact CD2-CG 3.91Å; Y522-E532 HydrophobicContact CE1-CB 3.65Å; Y522-E532 HydrophobicContact CE1-CG 3.76Å; Y522-E532 HydrophobicContact CE2-CG 4.1Å; Y522-E532 HydrophobicContact CG-CB 4.38Å; Y522-E532 HydrophobicContact CG-CG 3.64Å; Y522-P533 HydrophobicContact CE2-CG 4.12Å; Y522-P533 VanDerWaalsContact CZ-CD 3.48Å; Y522-P533 WeakPolarHBondContact OH-CD 3.34Å
523Q98.2Very high98.5Very high151 Ų15157.2 Ų57.271%0.70628%0.282SS*.Hα-helixtrans-59.3-39.5177.5-178.1174.8-9.100112K519 D520 K525K519-Q523 PolarHBondContact O-N 2.94Å; K519-Q523 VanDerWaalsContact O-N 3.07Å; D520-Q523 PolarHBondContact O-N 3.07Å; Q523-K525 VanDerWaalsContact C-N 3.35Å
524E97.4Very high98.4Very high90 Ų9066.5 Ų66.542%0.42133%0.325SS..THydrogen-bonded Turntrans-92.64.1-178.7-65173.8-157.100113K476 D520 Y522 T526K476-E524 IonicContact NZ-OE1 2.92Å; K476-E524 PolarHBondContact NZ-OE1 3.37Å; K476-E524 IonicContact NZ-OE2 3.05Å; K476-E524 PolarHBondContact NZ-OE2 3.5Å; D520-E524 WeakPolarHBondContact O-CB 3.32Å; D520-E524 WeakPolarHBondContact O-CG 3.46Å; D520-E524 PolarHBondContact O-N 3.25Å; Y522-E524 VanDerWaalsContact C-N 3.27Å; Y522-E524 PolarHBondContact O-N 3.32Å; E524-T526 HydrophobicContact CB-CG2 4.39Å; E524-T526 PolarHBondContact O-N 3.4Å
525K98.1Very high98.4Very high176 Ų17671 Ų7177%0.76535%0.349SS*.THydrogen-bonded Turntrans56.334.9179.2-54.5-178.7179.1179.90113.9A521 Y522 Q523A521-K525 PolarHBondContact O-N 2.71Å; A521-K525 VanDerWaalsContact O-N 3.1Å; Y522-K525 PolarHBondContact O-N 3.39Å; Y522-K525 VanDerWaalsContact O-N 3.14Å; Q523-K525 VanDerWaalsContact C-N 3.35Å
526T98Very high98.4Very high64 Ų6470.9 Ų70.939%0.39335%0.348SS..  trans-101.3-13.6176.854.70000113.2L470 A521 E524L470-T526 WeakPolarHBondContact CD1-OG1 3.44Å; A521-T526 WeakPolarHBondContact CA-OG1 3.36Å; A521-T526 PolarHBondContact O-N 2.75Å; A521-T526 PolarHBondContact O-OG1 3.13Å; E524-T526 HydrophobicContact CB-CG2 4.39Å; E524-T526 PolarHBondContact O-N 3.4Å
527A98.5Very high98.3Very high5 Ų570.4 Ų70.44%0.04135%0.347CS..  trans-68.8147.4172.600000112.3C468 A521 Y522 Y530C468-A527 HydrophobicContact CB-CB 4.05Å; A521-A527 HydrophobicContact CB-CB 3.96Å; A521-A527 PolarHBondContact O-N 3.15Å; A521-A527 VanDerWaalsContact O-N 3.17Å; Y522-A527 HydrophobicContact CD1-CB 3.74Å; Y522-A527 HydrophobicContact CD2-CB 4.38Å; Y522-A527 HydrophobicContact CE1-CB 3.7Å; Y522-A527 HydrophobicContact CE2-CB 4.35Å; Y522-A527 HydrophobicContact CG-CB 4.07Å; A527-Y530 WeakPolarHBondContact O-CE2 3.31Å
528T98.7Very high98.3Very high53 Ų5372.6 Ų72.633%0.32537%0.365SS..  trans-118.7-11.3178.364.80000114.4N239 C468 G469 R471 Y530N239-T528 PolarHBondContact ND2-OG1 3.32Å; C468-T528 PolarHBondContact O-N 2.85Å; G469-T528 WeakPolarHBondContact CA-OG1 3.46Å; G469-T528 WeakPolarHBondContact O-CB 3.38Å; G469-T528 WeakPolarHBondContact O-CG2 3.38Å; G469-T528 PolarHBondContact O-N 2.94Å; G469-T528 PolarHBondContact O-OG1 3.25Å; R471-T528 HydrophobicContact CG-CG2 3.65Å; T528-Y530 WeakPolarHBondContact O-CD2 3.12Å
529V98.6Very high98.3Very high50 Ų5074.4 Ų74.430%0.30337%0.373SS..SBendtrans-75.9127.7171.9176.10000108.9C468 Y522 F539C468-V529 PolarHBondContact O-N 3.12Å; C468-V529 VanDerWaalsContact O-N 3.11Å; Y522-V529 WeakPolarHBondContact CE1-O 3.12Å; Y522-V529 PolarHBondContact OH-O 3.19Å; V529-F539 HydrophobicContact CG1-CZ 4.11Å
530Y97.9Very high98.2Very high143 Ų14369.9 Ų69.956%0.56135%0.354SS*.SBendtrans-139.8153177.8-77.5-84.7000111.3Y522 A527 T528Y522-Y530 HydrophobicContact CE1-CE1 4.31Å; A527-Y530 WeakPolarHBondContact O-CE2 3.31Å; T528-Y530 WeakPolarHBondContact O-CD2 3.12Å
531P98.1Very high98.2Very high116 Ų11674.6 Ų74.675%0.75337%0.37SS*.SBendcis-68.2156.1-1.330.2-36000113
532E98.6Very high98.1Very high95 Ų9578.1 Ų78.144%0.44439%0.394SS..PPolyproline II helixtrans-59.1127.1175.9177.6179.2172.400109.9Y522 K536Y522-E532 HydrophobicContact CD1-CB 3.77Å; Y522-E532 HydrophobicContact CD1-CG 3.55Å; Y522-E532 HydrophobicContact CD2-CG 3.91Å; Y522-E532 HydrophobicContact CE1-CB 3.65Å; Y522-E532 HydrophobicContact CE1-CG 3.76Å; Y522-E532 HydrophobicContact CE2-CG 4.1Å; Y522-E532 HydrophobicContact CG-CB 4.38Å; Y522-E532 HydrophobicContact CG-CG 3.64Å; E532-K536 WeakPolarHBondContact OE1-CE 3.12Å; E532-K536 IonicContact OE1-NZ 3.03Å; E532-K536 PolarHBondContact OE1-NZ 2.84Å
533P98.1Very high98.1Very high19 Ų1980.6 Ų80.612%0.12341%0.406CS..PPolyproline II helixtrans-68.2137.4-179.328-34.7000110.5Y522 N535 K536 F539Y522-P533 HydrophobicContact CE2-CG 4.12Å; Y522-P533 VanDerWaalsContact CZ-CD 3.48Å; Y522-P533 WeakPolarHBondContact OH-CD 3.34Å; P533-N535 PolarHBondContact O-N 3.29Å; P533-K536 WeakPolarHBondContact O-CD 3.3Å; P533-K536 VanDerWaalsContact O-CE 3.24Å; P533-K536 WeakPolarHBondContact O-CE 3.22Å; P533-K536 PolarHBondContact O-NZ 3.46Å; P533-F539 HydrophobicContact CB-CB 3.64Å; P533-F539 HydrophobicContact CB-CD1 4.32Å; P533-F539 HydrophobicContact CB-CD2 3.82Å; P533-F539 HydrophobicContact CB-CE2 4.49Å; P533-F539 HydrophobicContact CB-CG 3.69Å; P533-F539 HydrophobicContact CG-CB 3.89Å; P533-F539 HydrophobicContact CG-CD1 3.71Å; P533-F539 HydrophobicContact CG-CD2 4Å; P533-F539 HydrophobicContact CG-CE1 4.12Å; P533-F539 HydrophobicContact CG-CE2 4.39Å; P533-F539 HydrophobicContact CG-CG 3.6Å; P533-F539 HydrophobicContact CG-CZ 4.41Å
534Q97.8Very high98.1Very high195 Ų19574.2 Ų74.291%0.91138%0.377SS*.SBendtrans-63.2-45.2179.4-169.8174.35.300111.8
535N98.3Very high98.1Very high94 Ų9470.7 Ų70.750%0.50336%0.36SS..  trans-110.3111.2175-176.6-23.7000110.3P533 E537 A538 F539P533-N535 PolarHBondContact O-N 3.29Å; N535-E537 PolarHBondContact OD1-N 3.42Å; N535-E537 VanDerWaalsContact OD1-N 3.12Å; N535-A538 HydrophobicContact CB-CB 3.99Å; N535-A538 PolarHBondContact OD1-N 3.49Å; N535-F539 VanDerWaalsContact O-CB 3.24Å; N535-F539 WeakPolarHBondContact O-CB 3.33Å; N535-F539 PolarHBondContact O-N 2.66Å
536K98.4Very high98.1Very high33 Ų3363.6 Ų63.614%0.14333%0.332CS..Hα-helixtrans-71.8-38.8-174.8-78.466177.2171.10112.1E515 V518 K519 E532 P533 F539 V540E515-K536 HydrophobicContact CG-CB 4.48Å; V518-K536 HydrophobicContact CG1-CB 4.25Å; V518-K536 HydrophobicContact CG1-CG 3.79Å; K519-K536 HydrophobicContact CG-CB 4.14Å; K519-K536 HydrophobicContact CG-CG 4.03Å; E532-K536 WeakPolarHBondContact OE1-CE 3.12Å; E532-K536 IonicContact OE1-NZ 3.03Å; E532-K536 PolarHBondContact OE1-NZ 2.84Å; P533-K536 WeakPolarHBondContact O-CD 3.3Å; P533-K536 VanDerWaalsContact O-CE 3.24Å; P533-K536 WeakPolarHBondContact O-CE 3.22Å; P533-K536 PolarHBondContact O-NZ 3.46Å; K536-F539 PolarHBondContact O-N 3Å; K536-V540 WeakPolarHBondContact O-CG2 3.46Å; K536-V540 PolarHBondContact O-N 2.87Å
537E98.1Very high98.1Very high65 Ų6561.4 Ų61.430%0.30432%0.319SS..Hα-helixtrans-65.7-50.3177.9-169.5-161.8162.300110.7L511 E515 N535 F539 V540 R541L511-E537 HydrophobicContact CD1-CG 4.47Å; L511-E537 HydrophobicContact CD2-CG 4.38Å; E515-E537 HydrophobicContact CG-CB 4.27Å; N535-E537 PolarHBondContact OD1-N 3.42Å; N535-E537 VanDerWaalsContact OD1-N 3.12Å; E537-F539 VanDerWaalsContact C-N 3.27Å; E537-F539 PolarHBondContact O-N 2.83Å; E537-V540 PolarHBondContact O-N 3.5Å; E537-V540 VanDerWaalsContact O-N 3.16Å; E537-R541 WeakPolarHBondContact O-CG 3.48Å; E537-R541 PolarHBondContact O-N 3.09Å; E537-R541 IonicContact OE1-CZ 3.89Å; E537-R541 VanDerWaalsContact OE1-CZ 3.23Å; E537-R541 IonicContact OE1-NE 3.51Å; E537-R541 PolarHBondContact OE1-NE 3.23Å; E537-R541 IonicContact OE1-NH2 2.71Å; E537-R541 PolarHBondContact OE1-NH2 3.23Å
538A97.9Very high98Very high48 Ų4864.8 Ų64.840%0.39734%0.336SS..Hα-helixtrans-60.8-38.5178.400000111.7N535 R541 S542N535-A538 HydrophobicContact CB-CB 3.99Å; N535-A538 PolarHBondContact OD1-N 3.49Å; A538-R541 PolarHBondContact O-N 2.86Å; A538-S542 WeakPolarHBondContact O-CB 3.37Å; A538-S542 PolarHBondContact O-N 3.04Å
539F98.6Very high98Very high39 Ų3964 Ų6417%0.17133%0.328CS..Hα-helixtrans-59.7-49173.2170.1-106.8000112.3A467 V518 V529 P533 N535 K536 E537 S542 Q543A467-F539 HydrophobicContact CB-CE1 4.19Å; A467-F539 VanDerWaalsContact O-CE1 3.32Å; A467-F539 WeakPolarHBondContact O-CE1 3.22Å; A467-F539 VanDerWaalsContact O-CZ 3.23Å; A467-F539 WeakPolarHBondContact O-CZ 3.42Å; V518-F539 HydrophobicContact CG1-CD1 4.41Å; V518-F539 HydrophobicContact CG1-CE1 4.48Å; V529-F539 HydrophobicContact CG1-CZ 4.11Å; P533-F539 HydrophobicContact CB-CB 3.64Å; P533-F539 HydrophobicContact CB-CD1 4.32Å; P533-F539 HydrophobicContact CB-CD2 3.82Å; P533-F539 HydrophobicContact CB-CE2 4.49Å; P533-F539 HydrophobicContact CB-CG 3.69Å; P533-F539 HydrophobicContact CG-CB 3.89Å; P533-F539 HydrophobicContact CG-CD1 3.71Å; P533-F539 HydrophobicContact CG-CD2 4Å; P533-F539 HydrophobicContact CG-CE1 4.12Å; P533-F539 HydrophobicContact CG-CE2 4.39Å; P533-F539 HydrophobicContact CG-CG 3.6Å; P533-F539 HydrophobicContact CG-CZ 4.41Å; N535-F539 VanDerWaalsContact O-CB 3.24Å; N535-F539 WeakPolarHBondContact O-CB 3.33Å; N535-F539 PolarHBondContact O-N 2.66Å; K536-F539 PolarHBondContact O-N 3Å; E537-F539 VanDerWaalsContact C-N 3.27Å; E537-F539 PolarHBondContact O-N 2.83Å; F539-S542 PolarHBondContact O-N 3.01Å; F539-S542 PolarHBondContact O-OG 3.33Å; F539-Q543 VanDerWaalsContact CE1-NE2 3.26Å; F539-Q543 PolarHBondContact O-N 3.19Å
540V98.4Very high97.9Very high0 Ų063 Ų630%032%0.32CS..Hα-helixtrans-62.9-48177.4175.90000110.7L463 L511 A514 V518 K536 E537 S542 Q543 M544L463-V540 HydrophobicContact CD1-CG1 4.47Å; L463-V540 HydrophobicContact CD2-CG1 3.49Å; L463-V540 VanDerWaalsContact CD2-CG1 3.49Å; L463-V540 HydrophobicContact CG-CG1 3.95Å; L511-V540 HydrophobicContact CD1-CB 3.87Å; L511-V540 HydrophobicContact CD1-CG1 3.49Å; L511-V540 VanDerWaalsContact CD1-CG1 3.49Å; A514-V540 HydrophobicContact CB-CG1 3.85Å; A514-V540 HydrophobicContact CB-CG2 4.48Å; V518-V540 HydrophobicContact CG2-CG2 3.83Å; K536-V540 WeakPolarHBondContact O-CG2 3.46Å; K536-V540 PolarHBondContact O-N 2.87Å; E537-V540 PolarHBondContact O-N 3.5Å; E537-V540 VanDerWaalsContact O-N 3.16Å; V540-S542 VanDerWaalsContact C-N 3.27Å; V540-S542 PolarHBondContact O-N 2.87Å; V540-Q543 PolarHBondContact O-N 2.91Å; V540-M544 PolarHBondContact O-N 3.3Å
541R98Very high97.8Very high116 Ų11659.7 Ų59.744%0.43831%0.31SS..Hα-helixtrans-56.2-39.4177.7-72.5-175.3-177-80.70.8112.6L511 E537 A538 Q543 M544L511-R541 HydrophobicContact CD1-CG 3.88Å; L511-R541 HydrophobicContact CD2-CG 3.89Å; E537-R541 WeakPolarHBondContact O-CG 3.48Å; E537-R541 PolarHBondContact O-N 3.09Å; E537-R541 IonicContact OE1-CZ 3.89Å; E537-R541 VanDerWaalsContact OE1-CZ 3.23Å; E537-R541 IonicContact OE1-NE 3.51Å; E537-R541 PolarHBondContact OE1-NE 3.23Å; E537-R541 IonicContact OE1-NH2 2.71Å; E537-R541 PolarHBondContact OE1-NH2 3.23Å; A538-R541 PolarHBondContact O-N 2.86Å; R541-Q543 PolarHBondContact O-N 3.03Å; R541-M544 PolarHBondContact O-N 3.04Å
542S97Very high97.7Very high76 Ų7654.5 Ų54.553%0.53128%0.276SS..Hα-helixtrans-62.6-26178.277.80000113.3A538 F539 V540A538-S542 WeakPolarHBondContact O-CB 3.37Å; A538-S542 PolarHBondContact O-N 3.04Å; F539-S542 PolarHBondContact O-N 3.01Å; F539-S542 PolarHBondContact O-OG 3.33Å; V540-S542 VanDerWaalsContact C-N 3.27Å; V540-S542 PolarHBondContact O-N 2.87Å
543Q96.9Very high97.6Very high64 Ų6451 Ų5130%0.29926%0.26SS..Hα-helixtrans-91.6-18.5178.7-64.2-168.654.600113.5F539 V540 R541F539-Q543 VanDerWaalsContact CE1-NE2 3.26Å; F539-Q543 PolarHBondContact O-N 3.19Å; V540-Q543 PolarHBondContact O-N 2.91Å; R541-Q543 PolarHBondContact O-N 3.03Å
544M98.4Very high97.5Very high18 Ų1853.8 Ų53.89%0.08928%0.278CS..SBendtrans-64.4138.6179.3-67.9179.483.700111.1R7 G182 L463 L511 V540 R541 S546R7-M544 PolarHBondContact NH1-O 2.77Å; R7-M544 PolarHBondContact NH2-O 3.23Å; R7-M544 VanDerWaalsContact NH2-O 3.13Å; G182-M544 CarbonylContact O-C 3.43Å; G182-M544 WeakPolarHBondContact O-CA 3.47Å; L463-M544 HydrophobicContact CD1-CG 4.18Å; L463-M544 HydrophobicContact CD2-CE 4.23Å; L463-M544 HydrophobicContact CD2-CG 3.91Å; L463-M544 HydrophobicContact CD2-SD 4.16Å; L511-M544 HydrophobicContact CB-SD 4.3Å; L511-M544 HydrophobicContact CD1-SD 4.05Å; V540-M544 PolarHBondContact O-N 3.3Å; R541-M544 PolarHBondContact O-N 3.04Å; M544-S546 PolarHBondContact O-N 3.22Å
545Y98.1Very high97.3Very high15 Ų1548.4 Ų48.46%0.05926%0.256CS..PPolyproline II helixtrans-63.3128.4175.3-177.8-105.2000110.8K84 Y87 T178 G182 M183 P185 R507 T547K84-Y545 HydrophobicContact CD-CE2 4.45Å; K84-Y545 WeakPolarHBondContact CD-OH 3.44Å; K84-Y545 WeakPolarHBondContact CE-OH 3.38Å; K84-Y545 WeakPolarHBondContact CG-OH 3.45Å; Y87-Y545 AromaticContact CD2-CE1 3.83Å; Y87-Y545 HydrophobicContact CD2-CE1 3.83Å; Y87-Y545 HydrophobicContact CG-CE1 4.15Å; T178-Y545 HydrophobicContact CG2-CD1 3.61Å; T178-Y545 HydrophobicContact CG2-CE1 4.04Å; T178-Y545 HydrophobicContact CG2-CG 4.13Å; G182-Y545 WeakPolarHBondContact O-CB 3.36Å; G182-Y545 PolarHBondContact O-N 3.2Å; M183-Y545 WeakPolarHBondContact O-CB 3.42Å; P185-Y545 HydrophobicContact CG-CD2 4.39Å; P185-Y545 HydrophobicContact CG-CE2 4Å; R507-Y545 PolarHBondContact NH2-O 2.97Å; R507-Y545 VanDerWaalsContact NH2-O 3.12Å; Y545-T547 HydrophobicContact CE1-CG2 4.34Å
546S97.3Very high97.1Very high27 Ų2749.2 Ų49.219%0.18927%0.267CS..PPolyproline II helixtrans-94.6139.5168.5174.60000109.8K84 M544 D548K84-S546 PolarHBondContact NZ-O 3.41Å; M544-S546 PolarHBondContact O-N 3.22Å; S546-D548 VanDerWaalsContact C-N 3.29Å; S546-D548 PolarHBondContact OG-N 3.03Å; S546-D548 VanDerWaalsContact OG-N 3.13Å; S546-D548 PolarHBondContact OG-OD2 3.43Å
547T98Very high96.9Very high18 Ų1855.7 Ų55.711%0.1129%0.292CS..  trans-80.7-10.417551.90000112.9Q51 K84 K88 T91 Y545Q51-T547 PolarHBondContact NE2-O 3.3Å; Q51-T547 PolarHBondContact OE1-O 3.45Å; K84-T547 WeakPolarHBondContact CD-O 3.45Å; K88-T547 WeakPolarHBondContact CD-OG1 3.45Å; T91-T547 HydrophobicContact CG2-CG2 4.47Å; Y545-T547 HydrophobicContact CE1-CG2 4.34Å
548D97.8Very high96.9Very high76 Ų7657.2 Ų57.241%0.40631%0.31SS..SBendtrans-72143.7178.2-54.4-33.7000110.9K84 K88 S546 D550K84-D548 VanDerWaalsContact CD-O 3.26Å; K84-D548 WeakPolarHBondContact CD-O 3.49Å; K84-D548 WeakPolarHBondContact CE-O 3.39Å; K84-D548 PolarHBondContact NZ-O 3.19Å; K88-D548 IonicContact NZ-OD1 3.63Å; K88-D548 PolarHBondContact NZ-OD1 3.24Å; S546-D548 VanDerWaalsContact C-N 3.29Å; S546-D548 PolarHBondContact OG-N 3.03Å; S546-D548 VanDerWaalsContact OG-N 3.13Å; S546-D548 PolarHBondContact OG-OD2 3.43Å; D548-D550 PolarHBondContact O-N 3.35Å
549Y98.2Very high96.8Very high38 Ų3862.5 Ų62.515%0.14932%0.32CS..PPolyproline II helixtrans-64.9128.9-179.3-69.5-62000111.9K26 A29 Q51 Q54 N82 K84K26-Y549 HydrophobicContact CB-CD1 4.03Å; K26-Y549 HydrophobicContact CB-CE1 3.81Å; K26-Y549 HydrophobicContact CB-CE2 4.44Å; K26-Y549 HydrophobicContact CB-CG 4.42Å; K26-Y549 HydrophobicContact CD-CD1 3.93Å; K26-Y549 HydrophobicContact CD-CD2 4.46Å; K26-Y549 HydrophobicContact CD-CG 3.86Å; K26-Y549 HydrophobicContact CG-CD1 3.56Å; K26-Y549 HydrophobicContact CG-CE1 3.81Å; K26-Y549 HydrophobicContact CG-CG 4.01Å; A29-Y549 HydrophobicContact CB-CD2 3.99Å; A29-Y549 HydrophobicContact CB-CE2 3.41Å; A29-Y549 VanDerWaalsContact CB-CE2 3.41Å; Q51-Y549 HydrophobicContact CB-CD2 4.43Å; Q51-Y549 HydrophobicContact CB-CE2 3.96Å; Q51-Y549 HydrophobicContact CG-CD2 4.37Å; Q51-Y549 HydrophobicContact CG-CE2 3.7Å; Q54-Y549 PolarHBondContact NE2-OH 3.4Å; Q54-Y549 PolarHBondContact OE1-OH 3.08Å; N82-Y549 PolarHBondContact ND2-OH 2.91Å; N82-Y549 PolarHBondContact OD1-OH 3.22Å; K84-Y549 HydrophobicContact CB-CD1 3.65Å; K84-Y549 HydrophobicContact CB-CE1 3.55Å; K84-Y549 HydrophobicContact CG-CD1 3.98Å; K84-Y549 HydrophobicContact CG-CE1 4.32Å
550D95.4Very high96.7Very high28 Ų2865.1 Ų65.115%0.1534%0.341CS..PPolyproline II helixtrans-75.6146.6175.4-52.3-46.5000110.2R7 R9 K26 K84 D548 I552R7-D550 WeakPolarHBondContact CB-OD1 3.38Å; R7-D550 CarbonylContact O-C 3.53Å; R7-D550 WeakPolarHBondContact O-CA 3.2Å; R7-D550 WeakPolarHBondContact O-CB 3.35Å; R9-D550 HydrophobicContact CB-CB 4.19Å; K26-D550 WeakPolarHBondContact CE-O 3.4Å; K26-D550 PolarHBondContact NZ-O 3.47Å; K84-D550 WeakPolarHBondContact CE-OD2 3.25Å; K84-D550 VanDerWaalsContact NZ-CG 3.28Å; K84-D550 IonicContact NZ-OD1 3.76Å; K84-D550 PolarHBondContact NZ-OD1 3.22Å; K84-D550 IonicContact NZ-OD2 3.81Å; K84-D550 PolarHBondContact NZ-OD2 3.33Å; D548-D550 PolarHBondContact O-N 3.35Å; D550-I552 PolarHBondContact O-N 3.45Å
551Q96.3Very high96.6Very high74 Ų7471 Ų7135%0.34637%0.368SS..BIsolated β-bridgetrans-72.6122.8171.4179.5152.3-46.300109.6P6 R7 R9 L553P6-Q551 HydrophobicContact CB-CB 4.46Å; R7-Q551 PolarHBondContact O-N 3.11Å; R9-Q551 PolarHBondContact N-O 3.17Å; Q551-L553 HydrophobicContact CG-CB 4.42Å
552I96.8Very high96.4Very high6 Ų673.8 Ų73.83%0.03139%0.386CS..  trans-109.2-1.3-177.565.1173.4000114.6R9 T11 L18 L24 F30 L38 D550R9-I552 HydrophobicContact CB-CG2 4.35Å; R9-I552 VanDerWaalsContact O-CA 3.29Å; R9-I552 WeakPolarHBondContact O-CA 3.24Å; T11-I552 HydrophobicContact CG2-CB 4.21Å; L18-I552 HydrophobicContact CD1-CD1 4.12Å; L24-I552 HydrophobicContact CD2-CG2 4.27Å; F30-I552 HydrophobicContact CE1-CD1 3.81Å; F30-I552 HydrophobicContact CZ-CD1 4.34Å; L38-I552 HydrophobicContact CD1-CD1 3.68Å; L38-I552 HydrophobicContact CD1-CG1 3.98Å; D550-I552 PolarHBondContact O-N 3.45Å
553L96.6Very high96.3Very high22 Ų2274.6 Ų74.612%0.11539%0.388CS..SBendtrans-73.9150.6170.8-66.8-177.4000110.8E33 E34 Q37 L38 Q551E33-L553 HydrophobicContact CG-CD1 4.11Å; E34-L553 HydrophobicContact CG-CD1 3.85Å; E34-L553 HydrophobicContact CG-CD2 4.45Å; E34-L553 HydrophobicContact CG-CG 4Å; Q37-L553 HydrophobicContact CB-CD2 3.59Å; Q37-L553 HydrophobicContact CG-CD2 4.33Å; L38-L553 HydrophobicContact CD2-CD2 4.1Å; L38-L553 HydrophobicContact CG-CD2 4.04Å; Q551-L553 HydrophobicContact CG-CB 4.42Å
554P95Very high96.3Very high77 Ų7776.4 Ų76.450%0.540%0.397SS..  trans-59.4145.4170.827.5-34.6000110.6C556P554-C556 PolarHBondContact O-N 3.01Å
555D94.3Very high96.1Very high82 Ų8281.7 Ų81.744%0.43942%0.419SS..  trans-76.5115.9172.8-171.838.6000109.4R8R8-D555 IonicContact CZ-OD1 3.89Å; R8-D555 VanDerWaalsContact CZ-OD1 3.25Å; R8-D555 IonicContact CZ-OD2 2.85Å; R8-D555 IonicContact NH1-OD1 3.47Å; R8-D555 PolarHBondContact NH1-OD1 3.5Å; R8-D555 VanDerWaalsContact NH1-OD1 3.14Å; R8-D555 IonicContact NH1-OD2 2.78Å; R8-D555 PolarHBondContact NH1-OD2 2.89Å; R8-D555 IonicContact NH2-OD1 2.85Å; R8-D555 PolarHBondContact NH2-OD1 3.37Å; R8-D555 IonicContact NH2-OD2 3.97Å
556C93.6Very high95.9Very high111 Ų11188.4 Ų88.475%0.7545%0.454SS*.  trans-105.3122.1-178.8-66.60000109.5P554P554-C556 PolarHBondContact O-N 3.01Å
557Y95.1Very high95.7Very high169 Ų16996.1 Ų96.166%0.66349%0.487SS*.  trans-138.9148.1172.359.2-86.2000109.6W559Y557-W559 AromaticContact CE2-CD1 3.87Å; Y557-W559 AromaticContact CE2-NE1 3.5Å
558S96.3Very high95.3Very high98 Ų98101.6 Ų101.669%0.68552%0.521SS*.PPolyproline II helixtrans-86.1156.6178.751.90000111.6
559W96.1Very high94.5Very high158 Ų158106 Ų10660%0.59854%0.537SS*.PPolyproline II helixtrans-99168168.6-76.615.7000109.3Y557 E561 V563 Q564Y557-W559 AromaticContact CE2-CD1 3.87Å; Y557-W559 AromaticContact CE2-NE1 3.5Å; W559-E561 PolarHBondContact O-N 2.88Å; W559-V563 HydrophobicContact CB-CG2 4Å; W559-V563 HydrophobicContact CE3-CG2 4.02Å; W559-Q564 HydrophobicContact CB-CB 4.39Å; W559-Q564 PolarHBondContact O-OE1 2.98Å
560P97.3Very high93.3Very high95 Ų95110.5 Ų110.562%0.61757%0.568SS**PPolyproline II helixtrans-52.7130.5168.4-24.533.9000110.3E562 V563 Q564P560-E562 PolarHBondContact O-N 3.23Å; P560-V563 HydrophobicContact CB-CG2 4.16Å; P560-V563 HydrophobicContact CG-CG2 4.4Å; P560-V563 WeakPolarHBondContact O-CG2 3.43Å; P560-V563 PolarHBondContact O-N 2.96Å; P560-Q564 PolarHBondContact O-N 3.1Å
561E95.4Very high92Very high122 Ų122115.1 Ų115.157%0.5759%0.592SS**Hα-helixtrans-52.9-37.2-171.7-17959.1-152.400112.6W559 V563 Q564 K565W559-E561 PolarHBondContact O-N 2.88Å; E561-V563 VanDerWaalsContact C-N 3.25Å; E561-V563 PolarHBondContact O-N 2.92Å; E561-Q564 PolarHBondContact O-N 3.13Å; E561-Q564 VanDerWaalsContact O-N 3.15Å; E561-K565 WeakPolarHBondContact O-CG 3.34Å; E561-K565 PolarHBondContact O-N 3.05Å; E561-K565 VanDerWaalsContact O-N 3.13Å
562E94.7Very high89.9Confident175 Ų175124.4 Ų124.482%0.81864%0.636SS**Hα-helixtrans-57.2-35.3178.1-63.1-178.7177.200113.6P560P560-E562 PolarHBondContact O-N 3.23Å
563V94.5Very high89.6Confident94 Ų94130.3 Ų130.357%0.5767%0.666SS**Hα-helixtrans-95.4-11.5179.4-58.80000113.1W559 P560 E561W559-V563 HydrophobicContact CB-CG2 4Å; W559-V563 HydrophobicContact CE3-CG2 4.02Å; P560-V563 HydrophobicContact CB-CG2 4.16Å; P560-V563 HydrophobicContact CG-CG2 4.4Å; P560-V563 WeakPolarHBondContact O-CG2 3.43Å; P560-V563 PolarHBondContact O-N 2.96Å; E561-V563 VanDerWaalsContact C-N 3.25Å; E561-V563 PolarHBondContact O-N 2.92Å
564Q96.4Very high89.2Confident102 Ų102136 Ų13648%0.47770%0.695SS.*Hα-helixtrans-91.7-19.2179.2-168.3168.5-2.700112.8W559 P560 E561 I566W559-Q564 HydrophobicContact CB-CB 4.39Å; W559-Q564 PolarHBondContact O-OE1 2.98Å; P560-Q564 PolarHBondContact O-N 3.1Å; E561-Q564 PolarHBondContact O-N 3.13Å; E561-Q564 VanDerWaalsContact O-N 3.15Å; Q564-I566 PolarHBondContact O-N 3.38Å
565K94Very high88.9Confident129 Ų129139.3 Ų139.356%0.56171%0.706SS**SBendtrans-58135.9178.9-80.5172.3-171.9176.40112.5E561 Q567E561-K565 WeakPolarHBondContact O-CG 3.34Å; E561-K565 PolarHBondContact O-N 3.05Å; E561-K565 VanDerWaalsContact O-N 3.13Å; K565-Q567 PolarHBondContact O-N 2.83Å
566I95.1Very high88.6Confident156 Ų156142.6 Ų142.680%0.872%0.721SS**PPolyproline II helixtrans-69.3124.6169.8-58.9173.2000108.2Q564Q564-I566 PolarHBondContact O-N 3.38Å
567Q92.7Very high88.2Confident188 Ų188144.6 Ų144.688%0.87972%0.72SS**PPolyproline II helixtrans-70.8132.5179.2-60.9-177.313.500110.5K565K565-Q567 PolarHBondContact O-N 2.83Å
568T90.8Very high87.8Confident133 Ų133143 Ų14382%0.81672%0.723SS**  trans-114.3-3.7-17652.70000113.7V570T568-V570 PolarHBondContact O-N 3.14Å
569K80.8Confident87.2Confident169 Ų169146.2 Ų146.274%0.73573%0.726SS**  trans-86.7111.7-175.8-160.1-175.5-179.3-137.40110.7D571K569-D571 VanDerWaalsContact CE-OD1 3.31Å; K569-D571 WeakPolarHBondContact CE-OD1 3.37Å; K569-D571 IonicContact NZ-OD1 2.75Å; K569-D571 PolarHBondContact NZ-OD1 2.77Å
570V72.3Confident86.5Confident132 Ų132145.3 Ų145.380%0.874%0.736SS**  trans-98.8114.2161.4-174.30000105.1T568 Q572T568-V570 PolarHBondContact O-N 3.14Å; V570-Q572 PolarHBondContact O-N 2.78Å
571D67.8Low85.6Confident126 Ų126149.5 Ų149.567%0.67475%0.746SS**  trans-60.1123.9173.9-71.1-40.7000108.3K569K569-D571 VanDerWaalsContact CE-OD1 3.31Å; K569-D571 WeakPolarHBondContact CE-OD1 3.37Å; K569-D571 IonicContact NZ-OD1 2.75Å; K569-D571 PolarHBondContact NZ-OD1 2.77Å
572Q52.8Low84.7Confident268 Ų268152 Ų152100%1.25276%0.762SS**  trans-73.90173.9-79.5-174.2-17.200111.3V570V570-Q572 PolarHBondContact O-N 2.78Å

Retrieved 572 of 572 residues in 1353.1 ms (Link to these results)