A0A096NVY4_PAPAN Loading...

Presenilin AlphaSync

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

AlphaFold DB (P49768-6), UniProt , Accession A0A096NVY4, Species PAPAN (Papio anubis, Olive baboon), Gene PSEN1, Length 409 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure AlphaSync Parameters PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33.2	Very low	35.1	Very low	236 Å²	236	154.8 Å²	154.8	100%	1.163	83%	0.829	S	S	*	*				0	131.1	0	-82.2	171	176.3	0	0	107.2
2	T	38.4	Very low	34.8	Very low	126 Å²	126	157.3 Å²	157.3	77%	0.773	83%	0.832	S	S	*	*			trans	63.8	94.9	177.5	53.6	0	0	0	0	117.1
3	E	38.4	Very low	34.5	Very low	165 Å²	165	157.6 Å²	157.6	77%	0.771	84%	0.835	S	S	*	*				79.3	123.8	106.2	-64.5	-54.4	116.9	0	0	110.3
4	L	36.3	Very low	34.4	Very low	137 Å²	137	153.5 Å²	153.5	72%	0.717	83%	0.834	S	S	*	*			cis	-175.3	138.6	25.7	-135.9	145.9	0	0	0	107.1
5	P	37.4	Very low	34.2	Very low	122 Å²	122	156.7 Å²	156.7	79%	0.792	84%	0.841	S	S	*	*			trans	-103.4	136.7	171.5	34.9	-25.4	0	0	0	111.4
6	A	40.6	Very low	34	Very low	92 Å²	92	158.1 Å²	158.1	76%	0.76	84%	0.844	S	S	*	*			trans	-162.3	151.1	173.4	0	0	0	0	0	111.9
7	P	38.2	Very low	34	Very low	115 Å²	115	155.7 Å²	155.7	75%	0.747	84%	0.842	S	S	*	*				-122.6	174.5	-123.2	32.9	-16.4	0	0	0	115.8	S9	P7-S9 PolarHBondContact O-N 2.94Å
8	L	32.8	Very low	34	Very low	179 Å²	179	156.4 Å²	156.4	94%	0.937	84%	0.839	S	S	*	*			trans	-31.1	113.5	153.9	-88.8	143.3	0	0	0	113
9	S	28.6	Very low	34	Very low	92 Å²	92	156.7 Å²	156.7	64%	0.643	84%	0.841	S	S	*	*			trans	172	89.1	148.2	51.8	0	0	0	0	109.6	P7	P7-S9 PolarHBondContact O-N 2.94Å
10	Y	30.3	Very low	34	Very low	227 Å²	227	155.5 Å²	155.5	89%	0.89	83%	0.834	S	S	*	*	S	Bend	trans	-173.3	44.5	159.4	-104.2	-68.5	0	0	0	111.6
11	F	32.2	Very low	34.1	Very low	212 Å²	212	155.9 Å²	155.9	93%	0.93	83%	0.831	S	S	*	*	S	Bend	trans	-158.3	54.2	166.2	-106.8	-76.3	0	0	0	110
12	Q	31.1	Very low	34.3	Very low	184 Å²	184	152.4 Å²	152.4	86%	0.86	82%	0.816	S	S	*	*	S	Bend	trans	-149.1	32.3	172.7	-158.4	161.3	-17.5	0	0	112.3
13	N	30.7	Very low	34.2	Very low	162 Å²	162	151 Å²	151	87%	0.866	81%	0.811	S	S	*	*	S	Bend	trans	-144.2	20.7	179.9	-90.9	-19	0	0	0	114.8
14	A	33	Very low	34.1	Very low	100 Å²	100	148.3 Å²	148.3	83%	0.826	80%	0.802	S	S	*	*	S	Bend	trans	-119.4	12.4	176.7	0	0	0	0	0	114.1
15	Q	32.6	Very low	34.2	Very low	201 Å²	201	147 Å²	147	94%	0.939	80%	0.8	S	S	*	*	S	Bend	trans	-134.3	24.2	-176	-117.2	176.7	-38	0	0	113.9
16	M	30.9	Very low	34.3	Very low	180 Å²	180	147.4 Å²	147.4	89%	0.887	80%	0.8	S	S	*	*	S	Bend	trans	-126.2	20.5	-178.5	-144.7	174.2	-110.3	0	0	114.3
17	S	33.1	Very low	34	Very low	117 Å²	117	152.5 Å²	152.5	82%	0.818	80%	0.799	S	S	*	*	S	Bend	trans	-125.6	12.4	-178.4	-83.3	0	0	0	0	116.3
18	E	34.9	Very low	34.1	Very low	168 Å²	168	151.8 Å²	151.8	79%	0.785	80%	0.797	S	S	*	*	S	Bend	trans	-129.9	32.5	-179.6	-86	-173.2	121.2	0	0	113.9
19	D	33.9	Very low	34.3	Very low	163 Å²	163	151.6 Å²	151.6	87%	0.872	79%	0.791	S	S	*	*	S	Bend	trans	-129.4	19.4	173.2	-83.7	-35.3	0	0	0	114.3
20	N	33.9	Very low	34.8	Very low	132 Å²	132	153.1 Å²	153.1	71%	0.706	79%	0.792	S	S	*	*	S	Bend	trans	-116.9	14.5	178.7	-122	-1.8	0	0	0	114.9
21	H	36.2	Very low	35.2	Very low	164 Å²	164	149.1 Å²	149.1	76%	0.759	79%	0.786	S	S	*	*	S	Bend	trans	-115.4	6.5	-177.4	-88.9	-70.8	0	0	0	116.1
22	L	36.3	Very low	35.5	Very low	163 Å²	163	146.4 Å²	146.4	85%	0.853	78%	0.781	S	S	*	*	S	Bend	trans	-111.8	0.7	173.6	-116.3	85.1	0	0	0	115.8
23	S	36.8	Very low	35.8	Very low	95 Å²	95	148.1 Å²	148.1	66%	0.664	78%	0.78	S	S	*	*	S	Bend	trans	-105.2	3.6	177.7	-69.7	0	0	0	0	114.9
24	N	36.4	Very low	36.2	Very low	110 Å²	110	149.3 Å²	149.3	59%	0.588	78%	0.78	S	S	*	*	S	Bend	trans	-112.8	3.6	-179.9	-80.3	-19.6	0	0	0	114.9
25	T	37.9	Very low	36.4	Very low	110 Å²	110	156.2 Å²	156.2	68%	0.675	79%	0.785	S	S	*	*	S	Bend	trans	-98.4	-13.9	177.7	-50.6	0	0	0	0	113.2
26	V	39	Very low	36.6	Very low	130 Å²	130	156 Å²	156	79%	0.788	78%	0.784	S	S	*	*	S	Bend	trans	-96.4	-3.5	174.7	-177.2	0	0	0	0	112.2
27	R	35.5	Very low	36.9	Very low	198 Å²	198	156.6 Å²	156.6	75%	0.747	79%	0.785	S	S	*	*	S	Bend	trans	-106.8	0	-177.8	-137.1	172.8	-172.3	169.8	1.6	115.4
28	S	39.3	Very low	37.1	Very low	100 Å²	100	159.3 Å²	159.3	70%	0.699	78%	0.784	S	S	*	*	S	Bend	trans	-107.4	7.9	175.5	-80.6	0	0	0	0	115
29	Q	38.8	Very low	37.4	Very low	175 Å²	175	157.7 Å²	157.7	82%	0.818	78%	0.781	S	S	*	*	S	Bend	trans	-109.3	1	175.9	-97.5	-177.3	-7.9	0	0	114.8
30	N	38.1	Very low	37.5	Very low	125 Å²	125	156.8 Å²	156.8	67%	0.668	78%	0.776	S	S	*	*	S	Bend	trans	-115.5	-0.2	-177.4	-124.3	10.9	0	0	0	115.5
31	D	38.9	Very low	37.7	Very low	143 Å²	143	162.6 Å²	162.6	77%	0.765	79%	0.788	S	S	*	*	S	Bend	trans	-102.3	8	-180	-87	-18.6	0	0	0	114.6
32	N	38.5	Very low	37.9	Very low	154 Å²	154	166.8 Å²	166.8	82%	0.824	80%	0.797	S	S	*	*	S	Bend	trans	-104.7	18.9	175.9	-80.9	-23.4	0	0	0	113.6
33	R	37.7	Very low	38.2	Very low	221 Å²	221	164.6 Å²	164.6	83%	0.834	80%	0.795	S	S	*	*	S	Bend	trans	-113.1	5.9	-175.4	-105.6	178.7	172.6	166.6	-2.5	116.5
34	E	39.3	Very low	38.5	Very low	187 Å²	187	168.2 Å²	168.2	87%	0.874	81%	0.806	S	S	*	*	S	Bend	trans	-129.8	21.8	-176.2	-66.1	-169.2	152.2	0	0	115.5
35	R	36.9	Very low	38.6	Very low	245 Å²	245	166.4 Å²	166.4	93%	0.925	81%	0.814	S	S	*	*	S	Bend	trans	-133.8	34.6	-177.5	-84	-168	177.5	-162.5	0.6	116.4
36	Q	36.1	Very low	39	Very low	195 Å²	195	170.4 Å²	170.4	91%	0.911	82%	0.824	S	S	*	*			trans	-138.2	53.6	175.6	-106.3	169.7	-13.7	0	0	112.5
37	E	36.8	Very low	39.1	Very low	193 Å²	193	169.7 Å²	169.7	90%	0.902	82%	0.822	S	S	*	*			trans	-120.1	67.4	163.4	-76.6	-165.2	148.9	0	0	110
38	H	38	Very low	39.7	Very low	174 Å²	174	168.9 Å²	168.9	81%	0.806	83%	0.827	S	S	*	*			trans	-174.6	97.4	156.4	-124.5	-59.5	0	0	0	109.5
39	N	40.4	Very low	39.8	Very low	134 Å²	134	169 Å²	169	72%	0.717	83%	0.825	S	S	*	*			trans	166.4	120.3	136	-93.2	-6.6	0	0	0	111.8
40	D	37.1	Very low	39.8	Very low	145 Å²	145	169.1 Å²	169.1	78%	0.775	83%	0.831	S	S	*	*			trans	51.5	95.7	136.5	-63.2	-34.6	0	0	0	119.1
41	R	38.6	Very low	39.9	Very low	254 Å²	254	168.2 Å²	168.2	96%	0.958	83%	0.834	S	S	*	*			trans	-133.8	95.5	146.6	-86.7	-172.9	170.5	173.8	-3.2	111.5
42	R	38.9	Very low	40	Very low	252 Å²	252	169.3 Å²	169.3	95%	0.951	84%	0.84	S	S	*	*			trans	-93.2	113.8	143.7	-81.2	-178.2	-178.1	172.2	1.5	107.2
43	S	42.9	Very low	40.1	Very low	116 Å²	116	165.2 Å²	165.2	81%	0.811	84%	0.835	S	S	*	*			trans	178.1	133.2	131.8	-165.9	0	0	0	0	110.4
44	L	43.3	Very low	40.4	Very low	172 Å²	172	166.5 Å²	166.5	90%	0.901	84%	0.839	S	S	*	*			trans	-53.7	152.7	178.2	-86.8	65.6	0	0	0	114.5
45	G	39.2	Very low	40.6	Very low	72 Å²	72	162.7 Å²	162.7	74%	0.742	83%	0.831	S	S	*	*			trans	132	108.8	132.5	0	0	0	0	0	117.6
46	H	45.8	Very low	41.1	Very low	193 Å²	193	160.7 Å²	160.7	89%	0.894	83%	0.832	S	S	*	*			trans	80.4	117.7	155.4	-73.7	-29.2	0	0	0	121.6
47	P	41.4	Very low	41.5	Very low	115 Å²	115	153.2 Å²	153.2	75%	0.747	81%	0.808	S	S	*	*			trans	-100.8	149.9	159.1	37	-26.2	0	0	0	111.7
48	E	47.5	Very low	42	Very low	182 Å²	182	149.6 Å²	149.6	85%	0.85	80%	0.795	S	S	*	*			trans	160.5	156.1	154.5	-83.9	-105.6	129.5	0	0	109.7
49	P	42.5	Very low	42.5	Very low	102 Å²	102	145.9 Å²	145.9	66%	0.662	79%	0.788	S	S	*	*				-128.7	173.5	-78.8	26.5	-3	0	0	0	114.6
50	L	37.8	Very low	42.8	Very low	177 Å²	177	148.6 Å²	148.6	93%	0.927	79%	0.788	S	S	*	*			trans	-12.7	122.5	165.5	-71.8	144.8	0	0	0	118.8
51	S	39.7	Very low	43.2	Very low	107 Å²	107	147.6 Å²	147.6	75%	0.748	78%	0.779	S	S	*	*			trans	-176.4	115.9	135.1	-173.4	0	0	0	0	110.7
52	N	42.6	Very low	44	Very low	165 Å²	165	139.2 Å²	139.2	88%	0.882	76%	0.756	S	S	*	*			trans	-175.2	99	142.8	-100.4	-14.9	0	0	0	111
53	G	39.2	Very low	44.8	Very low	69 Å²	69	131 Å²	131	71%	0.711	73%	0.733	S	S	*	*			trans	-90.1	138.6	161.8	0	0	0	0	0	111.5
54	R	45.4	Very low	45.4	Very low	247 Å²	247	130.2 Å²	130.2	93%	0.932	72%	0.717	S	S	*	*			trans	173.5	151	159	-106.2	169.7	178.5	178.5	0.1	110.4
55	P	43.5	Very low	45.9	Very low	107 Å²	107	127.5 Å²	127.5	70%	0.695	70%	0.699	S	S	*	*				-122.8	134.8	-61.7	31.5	-14.4	0	0	0	111.6	G57	P55-G57 PolarHBondContact O-N 3.45Å
56	Q	45.8	Very low	46.8	Very low	203 Å²	203	128.2 Å²	128.2	95%	0.949	69%	0.686	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76	29.2	179	-123.1	173.8	9.8	0	0	114.1
57	G	45.8	Very low	47.5	Very low	39 Å²	39	124.8 Å²	124.8	40%	0.402	67%	0.671	S	S	.	*	T	Hydrogen-bonded Turn	trans	-95.5	-26.6	-170.4	0	0	0	0	0	116.3	P55	P55-G57 PolarHBondContact O-N 3.45Å
58	N	46.8	Very low	48.4	Very low	117 Å²	117	125.3 Å²	125.3	63%	0.626	66%	0.663	S	S	*	*	H	α-helix	trans	-79.1	-27.7	-172.6	-92.2	28.3	0	0	0	114.4	R60 V62	N58-R60 VanDerWaalsContact C-N 3.27Å; N58-R60 PolarHBondContact O-N 3.3Å; N58-V62 WeakPolarHBondContact O-CG2 3.33Å; N58-V62 PolarHBondContact O-N 3.41Å
59	S	48.2	Very low	48.8	Very low	95 Å²	95	121.7 Å²	121.7	66%	0.664	65%	0.646	S	S	*	*	H	α-helix	trans	-72.2	-24	-178.4	-55.7	0	0	0	0	112.8	V63	S59-V63 VanDerWaalsContact O-CG2 3.27Å; S59-V63 WeakPolarHBondContact O-CG2 3.33Å; S59-V63 PolarHBondContact O-N 3.46Å
60	R	46.4	Very low	49.7	Very low	191 Å²	191	121.8 Å²	121.8	72%	0.721	64%	0.641	S	S	*	*	H	α-helix	trans	-81.4	-37.6	179.6	-153	173.2	-177	169.5	1.6	112	N58 V63 E64	N58-R60 VanDerWaalsContact C-N 3.27Å; N58-R60 PolarHBondContact O-N 3.3Å; R60-V63 PolarHBondContact O-N 3.04Å; R60-E64 PolarHBondContact O-N 3.03Å
61	Q	45.8	Very low	50.8	Low	125 Å²	125	119.6 Å²	119.6	58%	0.584	63%	0.626	S	S	*	*	H	α-helix	trans	-66.8	-36.3	174.8	-74.4	-175.9	-36	0	0	112.8	Q65	Q61-Q65 WeakPolarHBondContact O-CB 3.4Å; Q61-Q65 PolarHBondContact O-N 2.99Å
62	V	54.9	Low	51.8	Low	78 Å²	78	121 Å²	121	47%	0.473	62%	0.621	S	S	.	*	H	α-helix	trans	-69.8	-37.3	177.6	176.3	0	0	0	0	111.6	N58 Q65 D66	N58-V62 WeakPolarHBondContact O-CG2 3.33Å; N58-V62 PolarHBondContact O-N 3.41Å; V62-Q65 PolarHBondContact O-N 2.98Å; V62-D66 VanDerWaalsContact O-CG 3.29Å; V62-D66 PolarHBondContact O-N 3.02Å
63	V	56.9	Low	52.5	Low	78 Å²	78	116.1 Å²	116.1	47%	0.473	59%	0.594	S	S	.	*	H	α-helix	trans	-71.2	-40.3	177	175.7	0	0	0	0	111.7	S59 R60 Q65 D66 E67	S59-V63 VanDerWaalsContact O-CG2 3.27Å; S59-V63 WeakPolarHBondContact O-CG2 3.33Å; S59-V63 PolarHBondContact O-N 3.46Å; R60-V63 PolarHBondContact O-N 3.04Å; V63-Q65 VanDerWaalsContact C-N 3.31Å; V63-Q65 PolarHBondContact O-N 3.4Å; V63-D66 PolarHBondContact O-N 3.48Å; V63-E67 WeakPolarHBondContact O-CG 3.27Å; V63-E67 PolarHBondContact O-N 3.44Å
64	E	54.6	Low	53.9	Low	100 Å²	100	117 Å²	117	47%	0.467	59%	0.587	S	S	.	*	H	α-helix	trans	-63.4	-37.3	173.5	-76.4	173	174.5	0	0	111.6	R60 E68	R60-E64 PolarHBondContact O-N 3.03Å; E64-E68 WeakPolarHBondContact O-CB 3.43Å; E64-E68 WeakPolarHBondContact O-CG 3.4Å; E64-E68 PolarHBondContact O-N 3.02Å
65	Q	54.1	Low	55	Low	115 Å²	115	111.2 Å²	111.2	54%	0.537	57%	0.573	S	S	.	*	H	α-helix	trans	-67.7	-42	175.7	-126.7	170.5	-7.2	0	0	112.8	Q61 V62 V63 E68 E69	Q61-Q65 WeakPolarHBondContact O-CB 3.4Å; Q61-Q65 PolarHBondContact O-N 2.99Å; V62-Q65 PolarHBondContact O-N 2.98Å; V63-Q65 VanDerWaalsContact C-N 3.31Å; V63-Q65 PolarHBondContact O-N 3.4Å; Q65-E68 PolarHBondContact O-N 2.91Å; Q65-E69 WeakPolarHBondContact O-CB 3.43Å; Q65-E69 VanDerWaalsContact O-CG 3.3Å; Q65-E69 WeakPolarHBondContact O-CG 3.48Å; Q65-E69 PolarHBondContact O-N 2.77Å
66	D	57.5	Low	56.2	Low	88 Å²	88	113.4 Å²	113.4	47%	0.471	57%	0.572	S	S	.	*	H	α-helix	trans	-65.8	-38.1	177.2	-72	-23.4	0	0	0	111.4	V62 V63 D70	V62-D66 VanDerWaalsContact O-CG 3.29Å; V62-D66 PolarHBondContact O-N 3.02Å; V63-D66 PolarHBondContact O-N 3.48Å; D66-D70 WeakPolarHBondContact O-CB 3.3Å; D66-D70 PolarHBondContact O-N 3.47Å
67	E	60.2	Low	57.2	Low	121 Å²	121	105.6 Å²	105.6	57%	0.565	53%	0.534	S	S	*	.	H	α-helix	trans	-67.9	-43.6	175.3	-74	-178.9	176.1	0	0	112.2	V63 D70 E71	V63-E67 WeakPolarHBondContact O-CG 3.27Å; V63-E67 PolarHBondContact O-N 3.44Å; E67-D70 PolarHBondContact O-N 2.96Å; E67-E71 WeakPolarHBondContact O-CG 3.2Å; E67-E71 PolarHBondContact O-N 3.36Å
68	E	60.4	Low	58.7	Low	125 Å²	125	105.4 Å²	105.4	58%	0.584	53%	0.532	S	S	*	.	H	α-helix	trans	-62.9	-41.5	174.3	-76.1	179.3	179.8	0	0	111.8	E64 Q65 E71 E72	E64-E68 WeakPolarHBondContact O-CB 3.43Å; E64-E68 WeakPolarHBondContact O-CG 3.4Å; E64-E68 PolarHBondContact O-N 3.02Å; Q65-E68 PolarHBondContact O-N 2.91Å; E68-E71 PolarHBondContact O-N 2.95Å; E68-E72 WeakPolarHBondContact O-CB 3.38Å; E68-E72 WeakPolarHBondContact O-CG 3.44Å; E68-E72 PolarHBondContact O-N 2.92Å
69	E	57.8	Low	60.4	Low	106 Å²	106	102.6 Å²	102.6	50%	0.495	53%	0.525	S	S	.	.	H	α-helix	trans	-63.1	-42.2	175.8	-77.7	-174.1	-171.1	0	0	111.7	Q65 E72 L73	Q65-E69 WeakPolarHBondContact O-CB 3.43Å; Q65-E69 VanDerWaalsContact O-CG 3.3Å; Q65-E69 WeakPolarHBondContact O-CG 3.48Å; Q65-E69 PolarHBondContact O-N 2.77Å; E69-E72 PolarHBondContact O-N 3.46Å; E69-L73 WeakPolarHBondContact O-CB 3.4Å; E69-L73 WeakPolarHBondContact O-CD1 3.43Å; E69-L73 WeakPolarHBondContact O-CG 3.43Å; E69-L73 PolarHBondContact O-N 3.47Å
70	D	60.3	Low	62.1	Low	105 Å²	105	101.9 Å²	101.9	56%	0.561	51%	0.51	S	S	*	.	H	α-helix	trans	-65	-39.9	175.6	-84.7	-22	0	0	0	112.1	D66 E67 L73 T74	D66-D70 WeakPolarHBondContact O-CB 3.3Å; D66-D70 PolarHBondContact O-N 3.47Å; E67-D70 PolarHBondContact O-N 2.96Å; D70-L73 PolarHBondContact O-N 2.86Å; D70-T74 VanDerWaalsContact O-CG2 3.24Å; D70-T74 WeakPolarHBondContact O-CG2 3.35Å; D70-T74 PolarHBondContact O-N 3.48Å; D70-T74 PolarHBondContact O-OG1 2.89Å
71	E	61.5	Low	63.8	Low	131 Å²	131	94.2 Å²	94.2	61%	0.612	48%	0.482	S	S	*	.	H	α-helix	trans	-64.6	-48.6	174.2	-74.4	-170.1	176.8	0	0	111.9	E67 E68 L73 T74 L75	E67-E71 WeakPolarHBondContact O-CG 3.2Å; E67-E71 PolarHBondContact O-N 3.36Å; E68-E71 PolarHBondContact O-N 2.95Å; E71-L73 VanDerWaalsContact C-N 3.29Å; E71-L73 PolarHBondContact O-N 3.17Å; E71-T74 PolarHBondContact O-N 3.37Å; E71-T74 VanDerWaalsContact O-N 3.17Å; E71-T74 PolarHBondContact O-OG1 3.09Å; E71-L75 WeakPolarHBondContact O-CG 3.08Å; E71-L75 PolarHBondContact O-N 3.34Å
72	E	59.5	Low	65.7	Low	137 Å²	137	89.9 Å²	89.9	64%	0.64	46%	0.464	S	S	*	.	H	α-helix	trans	-59.3	-40.9	175.4	-77.2	-165.8	171	0	0	112	E68 E69 L75 K76	E68-E72 WeakPolarHBondContact O-CB 3.38Å; E68-E72 WeakPolarHBondContact O-CG 3.44Å; E68-E72 PolarHBondContact O-N 2.92Å; E69-E72 PolarHBondContact O-N 3.46Å; E72-L75 PolarHBondContact O-N 3.09Å; E72-K76 WeakPolarHBondContact O-CB 3.31Å; E72-K76 PolarHBondContact O-N 3.24Å
73	L	58.4	Low	67.3	Low	61 Å²	61	91.2 Å²	91.2	32%	0.319	47%	0.467	S	S	.	.	H	α-helix	trans	-60.5	-51.6	174.6	-78	170.5	0	0	0	109.9	E69 D70 E71 L75 K76 Y77	E69-L73 WeakPolarHBondContact O-CB 3.4Å; E69-L73 WeakPolarHBondContact O-CD1 3.43Å; E69-L73 WeakPolarHBondContact O-CG 3.43Å; E69-L73 PolarHBondContact O-N 3.47Å; D70-L73 PolarHBondContact O-N 2.86Å; E71-L73 VanDerWaalsContact C-N 3.29Å; E71-L73 PolarHBondContact O-N 3.17Å; L73-L75 VanDerWaalsContact C-N 3.32Å; L73-L75 PolarHBondContact O-N 3.25Å; L73-K76 PolarHBondContact O-N 3.5Å; L73-Y77 VanDerWaalsContact C-CD2 3.44Å; L73-Y77 HydrophobicContact CB-CD2 4.2Å; L73-Y77 HydrophobicContact CB-CE2 3.9Å; L73-Y77 HydrophobicContact CD2-CE2 3.94Å; L73-Y77 HydrophobicContact CG-CE2 4.48Å; L73-Y77 WeakPolarHBondContact O-CB 3.48Å; L73-Y77 WeakPolarHBondContact O-CD2 3.33Å; L73-Y77 PolarHBondContact O-N 2.85Å
74	T	67.5	Low	68.7	Low	89 Å²	89	89.5 Å²	89.5	55%	0.546	46%	0.455	S	S	.	.	H	α-helix	trans	-59.2	-40.3	179.3	64.1	0	0	0	0	112.9	D70 E71 Y77 G78	D70-T74 VanDerWaalsContact O-CG2 3.24Å; D70-T74 WeakPolarHBondContact O-CG2 3.35Å; D70-T74 PolarHBondContact O-N 3.48Å; D70-T74 PolarHBondContact O-OG1 2.89Å; E71-T74 PolarHBondContact O-N 3.37Å; E71-T74 VanDerWaalsContact O-N 3.17Å; E71-T74 PolarHBondContact O-OG1 3.09Å; T74-Y77 PolarHBondContact O-N 2.88Å; T74-G78 PolarHBondContact O-N 3.35Å
75	L	69.7	Low	70.3	Confident	125 Å²	125	84.8 Å²	84.8	65%	0.654	43%	0.433	S	S	*	.	H	α-helix	trans	-64.9	-45.2	175.4	-72.8	171.4	0	0	0	111.9	E71 E72 L73 Y77 G78 A79	E71-L75 WeakPolarHBondContact O-CG 3.08Å; E71-L75 PolarHBondContact O-N 3.34Å; E72-L75 PolarHBondContact O-N 3.09Å; L73-L75 VanDerWaalsContact C-N 3.32Å; L73-L75 PolarHBondContact O-N 3.25Å; L75-Y77 PolarHBondContact O-N 2.91Å; L75-G78 PolarHBondContact O-N 3.5Å; L75-A79 PolarHBondContact O-N 2.92Å
76	K	69	Low	72.2	Confident	153 Å²	153	81.5 Å²	81.5	67%	0.665	42%	0.417	S	S	*	.	H	α-helix	trans	-64.6	-40	178.1	-174.1	175.6	-176.7	173.9	0	111.9	E72 L73 K80	E72-K76 WeakPolarHBondContact O-CB 3.31Å; E72-K76 PolarHBondContact O-N 3.24Å; L73-K76 PolarHBondContact O-N 3.5Å; K76-K80 VanDerWaalsContact O-CB 3.27Å; K76-K80 WeakPolarHBondContact O-CB 3.5Å; K76-K80 PolarHBondContact O-N 3.34Å
77	Y	66.7	Low	73.9	Confident	39 Å²	39	81 Å²	81	15%	0.153	42%	0.417	C	S	.	.	H	α-helix	trans	-63.4	-46.2	173.1	-73.5	-65	0	0	0	110.4	L73 T74 L75 A79 K80 H81 N316	L73-Y77 VanDerWaalsContact C-CD2 3.44Å; L73-Y77 HydrophobicContact CB-CD2 4.2Å; L73-Y77 HydrophobicContact CB-CE2 3.9Å; L73-Y77 HydrophobicContact CD2-CE2 3.94Å; L73-Y77 HydrophobicContact CG-CE2 4.48Å; L73-Y77 WeakPolarHBondContact O-CB 3.48Å; L73-Y77 WeakPolarHBondContact O-CD2 3.33Å; L73-Y77 PolarHBondContact O-N 2.85Å; T74-Y77 PolarHBondContact O-N 2.88Å; L75-Y77 PolarHBondContact O-N 2.91Å; Y77-A79 PolarHBondContact O-N 2.84Å; Y77-K80 PolarHBondContact O-N 2.79Å; Y77-H81 VanDerWaalsContact C-CD2 3.49Å; Y77-H81 WeakPolarHBondContact O-CB 3.21Å; Y77-H81 PolarHBondContact O-CD2 3.29Å; Y77-H81 PolarHBondContact O-N 3.19Å; Y77-N316 VanDerWaalsContact CE1-OD1 3.31Å; Y77-N316 WeakPolarHBondContact CE1-OD1 3.45Å
78	G	76.5	Confident	75.5	Confident	35 Å²	35	75.4 Å²	75.4	36%	0.361	39%	0.391	S	S	.	.	H	α-helix	trans	-53.8	-54.6	175.1	0	0	0	0	0	112.7	T74 L75 K80 H81 V82	T74-G78 PolarHBondContact O-N 3.35Å; L75-G78 PolarHBondContact O-N 3.5Å; G78-K80 PolarHBondContact O-N 2.87Å; G78-H81 PolarHBondContact O-N 3.34Å; G78-V82 VanDerWaalsContact O-CG2 3.29Å; G78-V82 WeakPolarHBondContact O-CG2 3.24Å; G78-V82 PolarHBondContact O-N 3.44Å
79	A	82.9	Confident	77.2	Confident	57 Å²	57	69.5 Å²	69.5	47%	0.471	36%	0.363	S	S	.	.	H	α-helix	trans	-61.6	-42	179.7	0	0	0	0	0	112.6	L75 Y77 H81 V82 I83	L75-A79 PolarHBondContact O-N 2.92Å; Y77-A79 PolarHBondContact O-N 2.84Å; A79-H81 VanDerWaalsContact C-N 3.35Å; A79-H81 PolarHBondContact O-N 3.2Å; A79-V82 PolarHBondContact O-N 3.31Å; A79-I83 WeakPolarHBondContact O-CG1 3.49Å; A79-I83 PolarHBondContact O-N 3.07Å
80	K	83.7	Confident	79	Confident	80 Å²	80	66.2 Å²	66.2	35%	0.348	35%	0.35	S	S	.	.	H	α-helix	trans	-62.7	-41.8	176.3	-175.3	178.7	175.9	-179.1	0	111.7	K76 Y77 G78 I83 M84 N316	K76-K80 VanDerWaalsContact O-CB 3.27Å; K76-K80 WeakPolarHBondContact O-CB 3.5Å; K76-K80 PolarHBondContact O-N 3.34Å; Y77-K80 PolarHBondContact O-N 2.79Å; G78-K80 PolarHBondContact O-N 2.87Å; K80-I83 PolarHBondContact O-N 3.33Å; K80-M84 HydrophobicContact CD-CE 4.23Å; K80-M84 HydrophobicContact CG-CE 4.01Å; K80-M84 HydrophobicContact CG-SD 4.37Å; K80-M84 WeakPolarHBondContact O-CB 3.47Å; K80-M84 VanDerWaalsContact O-CG 3.26Å; K80-M84 WeakPolarHBondContact O-CG 2.85Å; K80-M84 PolarHBondContact O-N 3.43Å; K80-N316 PolarHBondContact NZ-OD1 3.47Å
81	H	81.1	Confident	80.7	Confident	31 Å²	31	65.4 Å²	65.4	14%	0.144	35%	0.346	C	S	.	.	H	α-helix	trans	-64.4	-40	177	-72.4	-42.8	0	0	0	112.5	Y77 G78 A79 M84 L85 R319 V321	Y77-H81 VanDerWaalsContact C-CD2 3.49Å; Y77-H81 WeakPolarHBondContact O-CB 3.21Å; Y77-H81 PolarHBondContact O-CD2 3.29Å; Y77-H81 PolarHBondContact O-N 3.19Å; G78-H81 PolarHBondContact O-N 3.34Å; A79-H81 VanDerWaalsContact C-N 3.35Å; A79-H81 PolarHBondContact O-N 3.2Å; H81-M84 PolarHBondContact O-N 2.91Å; H81-L85 PolarHBondContact O-N 3.45Å; H81-R319 PolarHBondContact CE1-O 3.44Å; H81-R319 PolarHBondContact NE2-O 2.91Å; H81-V321 HydrophobicContact CB-CG2 3.81Å
82	V	86.7	Confident	82.4	Confident	33 Å²	33	59.2 Å²	59.2	20%	0.2	32%	0.317	C	S	.	.	H	α-helix	trans	-60.9	-50.7	174.8	175.8	0	0	0	0	110.5	G78 A79 M84 L85 F86 L364	G78-V82 VanDerWaalsContact O-CG2 3.29Å; G78-V82 WeakPolarHBondContact O-CG2 3.24Å; G78-V82 PolarHBondContact O-N 3.44Å; A79-V82 PolarHBondContact O-N 3.31Å; V82-M84 VanDerWaalsContact C-N 3.3Å; V82-M84 PolarHBondContact O-N 2.91Å; V82-L85 PolarHBondContact O-N 3.48Å; V82-L85 VanDerWaalsContact O-N 3.08Å; V82-F86 HydrophobicContact CG1-CD1 3.87Å; V82-F86 HydrophobicContact CG1-CD2 4.36Å; V82-F86 HydrophobicContact CG1-CE1 3.69Å; V82-F86 HydrophobicContact CG1-CE2 4.18Å; V82-F86 HydrophobicContact CG1-CG 4.25Å; V82-F86 HydrophobicContact CG1-CZ 3.89Å; V82-F86 VanDerWaalsContact O-CD1 3.31Å; V82-F86 WeakPolarHBondContact O-CD1 3.4Å; V82-F86 PolarHBondContact O-N 3.39Å; V82-L364 HydrophobicContact CB-CD1 4.2Å; V82-L364 HydrophobicContact CG1-CD1 4.38Å; V82-L364 HydrophobicContact CG2-CB 4.38Å; V82-L364 HydrophobicContact CG2-CD1 3.73Å
83	I	88.3	Confident	84.2	Confident	107 Å²	107	52.8 Å²	52.8	55%	0.549	29%	0.287	S	S	.	.	H	α-helix	trans	-61.2	-40.4	179.2	-65.1	170.4	0	0	0	111.2	A79 K80 L85 F86 V87	A79-I83 WeakPolarHBondContact O-CG1 3.49Å; A79-I83 PolarHBondContact O-N 3.07Å; K80-I83 PolarHBondContact O-N 3.33Å; I83-L85 PolarHBondContact O-N 2.96Å; I83-F86 PolarHBondContact O-N 3.41Å; I83-V87 HydrophobicContact CG2-CG2 4.23Å; I83-V87 WeakPolarHBondContact O-CG2 3.31Å; I83-V87 PolarHBondContact O-N 3.39Å; I83-V87 VanDerWaalsContact O-N 3.11Å
84	M	86.8	Confident	86.1	Confident	41 Å²	41	54 Å²	54	20%	0.202	30%	0.297	C	S	.	.	H	α-helix	trans	-60.3	-27.4	177.1	-80.1	179.7	171.1	0	0	113.7	K80 H81 V82 P88 M292	K80-M84 HydrophobicContact CD-CE 4.23Å; K80-M84 HydrophobicContact CG-CE 4.01Å; K80-M84 HydrophobicContact CG-SD 4.37Å; K80-M84 WeakPolarHBondContact O-CB 3.47Å; K80-M84 VanDerWaalsContact O-CG 3.26Å; K80-M84 WeakPolarHBondContact O-CG 2.85Å; K80-M84 PolarHBondContact O-N 3.43Å; H81-M84 PolarHBondContact O-N 2.91Å; V82-M84 VanDerWaalsContact C-N 3.3Å; V82-M84 PolarHBondContact O-N 2.91Å; M84-P88 WeakPolarHBondContact O-CD 3.48Å; M84-P88 WeakPolarHBondContact O-CG 3.25Å; M84-M292 HydrophobicContact CE-CG 4.38Å; M84-M292 HydrophobicContact CE-SD 4.09Å
85	L	88.3	Confident	87.5	Confident	1 Å²	1	51.8 Å²	51.8	1%	0.005	28%	0.283	C	S	.	.	H	α-helix	trans	-90.4	-34.1	174.2	-70	-177.8	0	0	0	112.7	H81 V82 I83 V87 P88 V89 V321 L323 L360 L364	H81-L85 PolarHBondContact O-N 3.45Å; V82-L85 PolarHBondContact O-N 3.48Å; V82-L85 VanDerWaalsContact O-N 3.08Å; I83-L85 PolarHBondContact O-N 2.96Å; L85-V87 PolarHBondContact O-N 2.94Å; L85-P88 VanDerWaalsContact O-CD 3.27Å; L85-P88 WeakPolarHBondContact O-CD 3.49Å; L85-P88 WeakPolarHBondContact O-CG 3.36Å; L85-V89 WeakPolarHBondContact O-CB 3.4Å; L85-V89 VanDerWaalsContact O-CG2 3.24Å; L85-V89 WeakPolarHBondContact O-CG2 3.29Å; L85-V89 PolarHBondContact O-N 2.99Å; L85-V321 HydrophobicContact CD1-CB 4.44Å; L85-V321 HydrophobicContact CD1-CG1 3.66Å; L85-V321 HydrophobicContact CD2-CG1 4.24Å; L85-V321 HydrophobicContact CG-CG1 4.22Å; L85-L323 HydrophobicContact CD2-CB 3.86Å; L85-L323 HydrophobicContact CD2-CD2 4.05Å; L85-L360 HydrophobicContact CB-CD2 4.33Å; L85-L364 HydrophobicContact CD1-CD1 3.83Å; L85-L364 HydrophobicContact CD1-CD2 3.73Å; L85-L364 HydrophobicContact CD1-CG 4.31Å
86	F	93	Very high	88.8	Confident	46 Å²	46	45.9 Å²	45.9	20%	0.202	25%	0.252	C	S	.	.	H	α-helix	trans	-62.4	-44.4	179.8	-86.1	25.4	0	0	0	112.3	V82 I83 T90 L357 L360 C361	V82-F86 HydrophobicContact CG1-CD1 3.87Å; V82-F86 HydrophobicContact CG1-CD2 4.36Å; V82-F86 HydrophobicContact CG1-CE1 3.69Å; V82-F86 HydrophobicContact CG1-CE2 4.18Å; V82-F86 HydrophobicContact CG1-CG 4.25Å; V82-F86 HydrophobicContact CG1-CZ 3.89Å; V82-F86 VanDerWaalsContact O-CD1 3.31Å; V82-F86 WeakPolarHBondContact O-CD1 3.4Å; V82-F86 PolarHBondContact O-N 3.39Å; I83-F86 PolarHBondContact O-N 3.41Å; F86-T90 WeakPolarHBondContact O-CB 3.27Å; F86-T90 PolarHBondContact O-N 2.79Å; F86-T90 PolarHBondContact O-OG1 3.21Å; F86-L357 HydrophobicContact CD1-CD2 4.26Å; F86-L357 HydrophobicContact CD2-CD2 4.3Å; F86-L357 HydrophobicContact CE1-CD2 4.28Å; F86-L357 HydrophobicContact CE2-CB 4.21Å; F86-L357 HydrophobicContact CE2-CD1 4.44Å; F86-L357 HydrophobicContact CE2-CD2 4.34Å; F86-L357 HydrophobicContact CG-CD2 4.22Å; F86-L357 HydrophobicContact CZ-CB 4.01Å; F86-L357 HydrophobicContact CZ-CD2 4.27Å; F86-L357 VanDerWaalsContact CZ-O 3.31Å; F86-L357 WeakPolarHBondContact CZ-O 3.31Å; F86-L360 HydrophobicContact CD1-CD2 3.72Å; F86-L360 HydrophobicContact CD1-CG 4.41Å; F86-L360 HydrophobicContact CE1-CB 4.08Å; F86-L360 HydrophobicContact CE1-CD2 3.72Å; F86-L360 HydrophobicContact CE1-CG 3.96Å; F86-C361 HydrophobicContact CZ-CB 4.42Å; F86-C361 WeakPolarHBondContact CZ-SG 3.27Å
87	V	93.8	Very high	90.1	Very high	78 Å²	78	39.2 Å²	39.2	47%	0.473	22%	0.224	S	C	.	.	H	α-helix	trans	-56.6	-60.7	-179.3	172.5	0	0	0	0	111.8	I83 L85 V89 T90 L91	I83-V87 HydrophobicContact CG2-CG2 4.23Å; I83-V87 WeakPolarHBondContact O-CG2 3.31Å; I83-V87 PolarHBondContact O-N 3.39Å; I83-V87 VanDerWaalsContact O-N 3.11Å; L85-V87 PolarHBondContact O-N 2.94Å; V87-V89 VanDerWaalsContact C-N 3.32Å; V87-V89 PolarHBondContact O-N 3.01Å; V87-T90 PolarHBondContact O-N 3.17Å; V87-L91 HydrophobicContact CG1-CD1 3.6Å; V87-L91 WeakPolarHBondContact O-CD1 3.17Å; V87-L91 PolarHBondContact O-N 3.2Å
88	P	94.1	Very high	91.5	Very high	3 Å²	3	39.9 Å²	39.9	2%	0.019	24%	0.237	C	C	.	.	H	α-helix	trans	-64.9	-34.5	-176.1	29.4	-39.2	0	0	0	112.8	M84 L85 L91 C92 I227 Y288 F328	M84-P88 WeakPolarHBondContact O-CD 3.48Å; M84-P88 WeakPolarHBondContact O-CG 3.25Å; L85-P88 VanDerWaalsContact O-CD 3.27Å; L85-P88 WeakPolarHBondContact O-CD 3.49Å; L85-P88 WeakPolarHBondContact O-CG 3.36Å; P88-L91 PolarHBondContact O-N 2.88Å; P88-C92 WeakPolarHBondContact O-CB 3.19Å; P88-C92 PolarHBondContact O-N 3.32Å; P88-I227 HydrophobicContact CB-CD1 3.73Å; P88-I227 HydrophobicContact CB-CG1 4.09Å; P88-Y288 HydrophobicContact CB-CE1 4.25Å; P88-Y288 HydrophobicContact CB-CE2 3.83Å; P88-Y288 WeakPolarHBondContact CB-OH 3.14Å; P88-Y288 HydrophobicContact CG-CE1 3.77Å; P88-Y288 HydrophobicContact CG-CE2 4.28Å; P88-F328 HydrophobicContact CB-CE1 3.77Å; P88-F328 HydrophobicContact CB-CZ 4.19Å; P88-F328 HydrophobicContact CG-CE1 4.08Å; P88-F328 HydrophobicContact CG-CZ 4.16Å
89	V	95	Very high	92.5	Very high	1 Å²	1	38.3 Å²	38.3	1%	0.006	22%	0.221	C	C	.	.	H	α-helix	trans	-66	-45.1	177.1	172.6	0	0	0	0	110.1	L85 V87 C92 M93 L323 F328 Y331 L360	L85-V89 WeakPolarHBondContact O-CB 3.4Å; L85-V89 VanDerWaalsContact O-CG2 3.24Å; L85-V89 WeakPolarHBondContact O-CG2 3.29Å; L85-V89 PolarHBondContact O-N 2.99Å; V87-V89 VanDerWaalsContact C-N 3.32Å; V87-V89 PolarHBondContact O-N 3.01Å; V89-C92 WeakPolarHBondContact O-CB 3.31Å; V89-C92 PolarHBondContact O-N 3.49Å; V89-M93 HydrophobicContact CG1-CE 3.47Å; V89-M93 VanDerWaalsContact CG1-CE 3.47Å; V89-M93 HydrophobicContact CG1-SD 4.04Å; V89-M93 WeakPolarHBondContact O-CG 3.31Å; V89-M93 PolarHBondContact O-N 2.88Å; V89-L323 HydrophobicContact CG2-CD2 4.15Å; V89-F328 HydrophobicContact CB-CD1 4.48Å; V89-F328 HydrophobicContact CB-CE1 4.24Å; V89-F328 HydrophobicContact CG2-CD1 3.86Å; V89-F328 HydrophobicContact CG2-CE1 3.46Å; V89-F328 VanDerWaalsContact CG2-CE1 3.46Å; V89-F328 HydrophobicContact CG2-CZ 3.88Å; V89-Y331 HydrophobicContact CG1-CD2 3.97Å; V89-L360 HydrophobicContact CG2-CD2 4.38Å
90	T	96.4	Very high	93	Very high	37 Å²	37	36 Å²	36	23%	0.227	20%	0.201	C	C	.	.	H	α-helix	trans	-61.4	-46.7	176.1	-59.1	0	0	0	0	111.4	F86 V87 C92 M93 V94 F353	F86-T90 WeakPolarHBondContact O-CB 3.27Å; F86-T90 PolarHBondContact O-N 2.79Å; F86-T90 PolarHBondContact O-OG1 3.21Å; V87-T90 PolarHBondContact O-N 3.17Å; T90-C92 VanDerWaalsContact C-N 3.31Å; T90-C92 PolarHBondContact O-N 3.34Å; T90-M93 PolarHBondContact O-N 3.39Å; T90-V94 HydrophobicContact CG2-CG2 4.22Å; T90-V94 WeakPolarHBondContact O-CB 3.36Å; T90-V94 VanDerWaalsContact O-CG2 3.25Å; T90-V94 WeakPolarHBondContact O-CG2 3.42Å; T90-V94 PolarHBondContact O-N 3.48Å; T90-F353 HydrophobicContact CG2-CE2 3.81Å; T90-F353 HydrophobicContact CG2-CZ 3.67Å
91	L	96.6	Very high	93.5	Very high	89 Å²	89	35.8 Å²	35.8	47%	0.466	20%	0.2	S	C	.	.	H	α-helix	trans	-59.5	-42.9	176.8	-88.9	86.2	0	0	0	111.6	V87 P88 V94 V95 I227	V87-L91 HydrophobicContact CG1-CD1 3.6Å; V87-L91 WeakPolarHBondContact O-CD1 3.17Å; V87-L91 PolarHBondContact O-N 3.2Å; P88-L91 PolarHBondContact O-N 2.88Å; L91-V94 PolarHBondContact O-N 2.92Å; L91-V95 WeakPolarHBondContact O-CG2 3.36Å; L91-V95 PolarHBondContact O-N 3.45Å; L91-I227 HydrophobicContact CB-CG2 4.46Å
92	C	97.2	Very high	94.1	Very high	0 Å²	0	37 Å²	37	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-59.9	-48	177.9	-164.5	0	0	0	0	111.6	P88 V89 T90 V94 V95 V96 I227 F328 S332	P88-C92 WeakPolarHBondContact O-CB 3.19Å; P88-C92 PolarHBondContact O-N 3.32Å; V89-C92 WeakPolarHBondContact O-CB 3.31Å; V89-C92 PolarHBondContact O-N 3.49Å; T90-C92 VanDerWaalsContact C-N 3.31Å; T90-C92 PolarHBondContact O-N 3.34Å; C92-V94 PolarHBondContact O-N 3.44Å; C92-V95 PolarHBondContact O-N 2.75Å; C92-V96 WeakPolarHBondContact O-CG2 3.41Å; C92-V96 PolarHBondContact O-N 2.76Å; C92-I227 HydrophobicContact CB-CG2 3.95Å; C92-F328 HydrophobicContact CB-CD1 4.16Å; C92-S332 PolarHBondContact SG-OG 2.98Å
93	M	96.7	Very high	94.5	Very high	3 Å²	3	35.5 Å²	35.5	2%	0.015	20%	0.202	C	C	.	.	H	α-helix	trans	-62.1	-43.7	176.8	-67.3	165.3	174	0	0	112.2	V89 T90 V95 V96 V97 Y331 V335 F353 I356	V89-M93 HydrophobicContact CG1-CE 3.47Å; V89-M93 VanDerWaalsContact CG1-CE 3.47Å; V89-M93 HydrophobicContact CG1-SD 4.04Å; V89-M93 WeakPolarHBondContact O-CG 3.31Å; V89-M93 PolarHBondContact O-N 2.88Å; T90-M93 PolarHBondContact O-N 3.39Å; M93-V95 VanDerWaalsContact C-N 3.35Å; M93-V95 PolarHBondContact O-N 3.38Å; M93-V96 PolarHBondContact O-N 3.03Å; M93-V97 WeakPolarHBondContact O-CB 3.35Å; M93-V97 VanDerWaalsContact O-CG2 3.31Å; M93-V97 WeakPolarHBondContact O-CG2 3.2Å; M93-V97 PolarHBondContact O-N 2.78Å; M93-Y331 HydrophobicContact CE-CD2 4.48Å; M93-Y331 HydrophobicContact CE-CG 4.27Å; M93-V335 HydrophobicContact CE-CG2 4.2Å; M93-V335 HydrophobicContact CG-CG2 4.28Å; M93-V335 HydrophobicContact SD-CG2 4.22Å; M93-F353 HydrophobicContact SD-CD2 3.41Å; M93-F353 WeakPolarHBondContact SD-CD2 3.39Å; M93-F353 HydrophobicContact SD-CE2 3.65Å; M93-I356 HydrophobicContact CE-CB 4Å; M93-I356 HydrophobicContact CE-CD1 3.78Å; M93-I356 HydrophobicContact CE-CG2 3.5Å
94	V	97.2	Very high	94.7	Very high	86 Å²	86	34.5 Å²	34.5	52%	0.521	21%	0.205	S	C	.	.	H	α-helix	trans	-60.1	-45.4	177.8	168.1	0	0	0	0	110.7	T90 L91 C92 V96 A98	T90-V94 HydrophobicContact CG2-CG2 4.22Å; T90-V94 WeakPolarHBondContact O-CB 3.36Å; T90-V94 VanDerWaalsContact O-CG2 3.25Å; T90-V94 WeakPolarHBondContact O-CG2 3.42Å; T90-V94 PolarHBondContact O-N 3.48Å; L91-V94 PolarHBondContact O-N 2.92Å; C92-V94 PolarHBondContact O-N 3.44Å; V94-V96 PolarHBondContact O-N 3.35Å; V94-A98 WeakPolarHBondContact O-CB 3.11Å; V94-A98 PolarHBondContact O-N 3.4Å
95	V	97.3	Very high	94.9	Very high	43 Å²	43	34.7 Å²	34.7	26%	0.261	21%	0.205	S	C	.	.	H	α-helix	trans	-58.6	-49	176	170.6	0	0	0	0	110.3	L91 C92 M93 A98 T99 A231	L91-V95 WeakPolarHBondContact O-CG2 3.36Å; L91-V95 PolarHBondContact O-N 3.45Å; C92-V95 PolarHBondContact O-N 2.75Å; M93-V95 VanDerWaalsContact C-N 3.35Å; M93-V95 PolarHBondContact O-N 3.38Å; V95-A98 PolarHBondContact O-N 2.91Å; V95-T99 WeakPolarHBondContact O-CB 3.47Å; V95-T99 PolarHBondContact O-N 3.34Å; V95-T99 PolarHBondContact O-OG1 3.44Å; V95-A231 HydrophobicContact CB-CB 4.37Å; V95-A231 HydrophobicContact CG1-CB 3.82Å
96	V	97.4	Very high	95.1	Very high	0 Å²	0	35.4 Å²	35.4	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-64.8	-45.5	-178	172	0	0	0	0	112.3	C92 M93 V94 T99 I100 A231 A234 L235 I238	C92-V96 WeakPolarHBondContact O-CG2 3.41Å; C92-V96 PolarHBondContact O-N 2.76Å; M93-V96 PolarHBondContact O-N 3.03Å; V94-V96 PolarHBondContact O-N 3.35Å; V96-T99 PolarHBondContact O-N 3.21Å; V96-I100 HydrophobicContact CG1-CD1 3.68Å; V96-I100 WeakPolarHBondContact O-CD1 3.47Å; V96-I100 VanDerWaalsContact O-CG1 3.25Å; V96-I100 WeakPolarHBondContact O-CG1 3.31Å; V96-I100 PolarHBondContact O-N 3.11Å; V96-A231 HydrophobicContact CG2-CB 3.7Å; V96-A234 HydrophobicContact CG2-CB 4.09Å; V96-L235 HydrophobicContact CG1-CD2 4.3Å; V96-I238 HydrophobicContact CG1-CD1 3.73Å
97	V	96.4	Very high	95	Very high	14 Å²	14	36.4 Å²	36.4	9%	0.085	22%	0.217	C	C	.	.	H	α-helix	trans	-64.9	-45	178.1	172.5	0	0	0	0	111	M93 T99 I100 K101 V335 W346 T349	M93-V97 WeakPolarHBondContact O-CB 3.35Å; M93-V97 VanDerWaalsContact O-CG2 3.31Å; M93-V97 WeakPolarHBondContact O-CG2 3.2Å; M93-V97 PolarHBondContact O-N 2.78Å; V97-T99 VanDerWaalsContact C-N 3.33Å; V97-T99 PolarHBondContact O-N 3.13Å; V97-I100 PolarHBondContact O-N 3.19Å; V97-K101 HydrophobicContact CG1-CG 4.47Å; V97-K101 PolarHBondContact O-N 3.09Å; V97-V335 HydrophobicContact CG2-CG1 3.52Å; V97-W346 HydrophobicContact CG1-CH2 4.01Å; V97-W346 HydrophobicContact CG1-CZ3 3.74Å; V97-T349 HydrophobicContact CG1-CG2 4.29Å; V97-T349 HydrophobicContact CG2-CG2 3.97Å
98	A	96.3	Very high	94.8	Very high	52 Å²	52	40.8 Å²	40.8	43%	0.43	23%	0.225	S	C	.	.	H	α-helix	trans	-60.8	-43	176.9	0	0	0	0	0	111.3	V94 V95 S102	V94-A98 WeakPolarHBondContact O-CB 3.11Å; V94-A98 PolarHBondContact O-N 3.4Å; V95-A98 PolarHBondContact O-N 2.91Å; A98-S102 VanDerWaalsContact O-CB 3.26Å; A98-S102 WeakPolarHBondContact O-CB 3.34Å; A98-S102 PolarHBondContact O-N 3.07Å; A98-S102 PolarHBondContact O-OG 3.14Å
99	T	96.7	Very high	94.2	Very high	3 Å²	3	47.6 Å²	47.6	2%	0.018	26%	0.255	C	S	.	.	H	α-helix	trans	-61.7	-46.8	174.5	-60	0	0	0	0	111.5	V95 V96 V97 K101 S102 V103 Y106 Y181 L235	V95-T99 WeakPolarHBondContact O-CB 3.47Å; V95-T99 PolarHBondContact O-N 3.34Å; V95-T99 PolarHBondContact O-OG1 3.44Å; V96-T99 PolarHBondContact O-N 3.21Å; V97-T99 VanDerWaalsContact C-N 3.33Å; V97-T99 PolarHBondContact O-N 3.13Å; T99-K101 VanDerWaalsContact C-N 3.33Å; T99-K101 PolarHBondContact O-N 3.07Å; T99-S102 PolarHBondContact O-N 3.23Å; T99-S102 PolarHBondContact O-OG 3.06Å; T99-V103 HydrophobicContact CG2-CB 4.23Å; T99-V103 HydrophobicContact CG2-CG2 4.39Å; T99-V103 WeakPolarHBondContact O-CA 3.32Å; T99-V103 WeakPolarHBondContact O-CB 3.48Å; T99-V103 PolarHBondContact O-N 2.9Å; T99-Y106 HydrophobicContact CG2-CD2 3.62Å; T99-Y106 HydrophobicContact CG2-CE2 3.68Å; T99-Y181 HydrophobicContact CG2-CD2 4.4Å; T99-Y181 HydrophobicContact CG2-CE2 3.64Å; T99-Y181 PolarHBondContact OG1-OH 3.43Å; T99-L235 HydrophobicContact CG2-CD1 3.77Å; T99-L235 HydrophobicContact CG2-CD2 3.73Å; T99-L235 HydrophobicContact CG2-CG 4.42Å
100	I	94.9	Very high	93.3	Very high	8 Å²	8	51.5 Å²	51.5	4%	0.041	28%	0.276	C	S	.	.	H	α-helix	trans	-63.9	-39.4	-177.7	-71.5	164.9	0	0	0	111.9	V96 V97 T107 L235 I238 G336 A340	V96-I100 HydrophobicContact CG1-CD1 3.68Å; V96-I100 WeakPolarHBondContact O-CD1 3.47Å; V96-I100 VanDerWaalsContact O-CG1 3.25Å; V96-I100 WeakPolarHBondContact O-CG1 3.31Å; V96-I100 PolarHBondContact O-N 3.11Å; V97-I100 PolarHBondContact O-N 3.19Å; I100-T107 HydrophobicContact CG2-CG2 3.9Å; I100-L235 HydrophobicContact CG1-CD2 4.01Å; I100-I238 HydrophobicContact CD1-CD1 3.59Å; I100-I238 HydrophobicContact CD1-CG2 4.18Å; I100-G336 WeakPolarHBondContact CD1-O 3.26Å; I100-A340 HydrophobicContact CG2-CB 3.8Å
101	K	93.4	Very high	92.3	Very high	76 Å²	76	52 Å²	52	33%	0.33	29%	0.288	S	S	.	.	H	α-helix	trans	-77.7	-26.6	178.7	-67.5	-63.8	-159.7	-170.6	0	113	V97 T99 S339 D345 W346	V97-K101 HydrophobicContact CG1-CG 4.47Å; V97-K101 PolarHBondContact O-N 3.09Å; T99-K101 VanDerWaalsContact C-N 3.33Å; T99-K101 PolarHBondContact O-N 3.07Å; K101-S339 WeakPolarHBondContact CE-O 3.27Å; K101-S339 VanDerWaalsContact CE-OG 3.26Å; K101-S339 WeakPolarHBondContact CE-OG 3.34Å; K101-S339 PolarHBondContact NZ-O 2.71Å; K101-D345 PolarHBondContact NZ-O 3.4Å; K101-D345 IonicContact NZ-OD1 2.71Å; K101-D345 PolarHBondContact NZ-OD1 3.48Å; K101-W346 HydrophobicContact CG-CH2 4.12Å; K101-W346 HydrophobicContact CG-CZ2 4.12Å
102	S	94.4	Very high	91.4	Very high	56 Å²	56	51.4 Å²	51.4	39%	0.392	28%	0.283	S	S	.	.	H	α-helix	trans	-92.1	-41.8	179.6	57.8	0	0	0	0	113.7	A98 T99 T188	A98-S102 VanDerWaalsContact O-CB 3.26Å; A98-S102 WeakPolarHBondContact O-CB 3.34Å; A98-S102 PolarHBondContact O-N 3.07Å; A98-S102 PolarHBondContact O-OG 3.14Å; T99-S102 PolarHBondContact O-N 3.23Å; T99-S102 PolarHBondContact O-OG 3.06Å; S102-T188 WeakPolarHBondContact O-CG2 3.39Å
103	V	94.7	Very high	90.5	Very high	1 Å²	1	53.1 Å²	53.1	1%	0.006	29%	0.292	C	S	.	.			trans	-107.5	95.9	-173.8	-178.6	0	0	0	0	109.8	T99 F105 Y106 E184 V185 T188	T99-V103 HydrophobicContact CG2-CB 4.23Å; T99-V103 HydrophobicContact CG2-CG2 4.39Å; T99-V103 WeakPolarHBondContact O-CA 3.32Å; T99-V103 WeakPolarHBondContact O-CB 3.48Å; T99-V103 PolarHBondContact O-N 2.9Å; V103-F105 HydrophobicContact CG1-CB 3.98Å; V103-F105 PolarHBondContact O-N 3.22Å; V103-F105 VanDerWaalsContact O-N 3.09Å; V103-Y106 HydrophobicContact CB-CD2 4.12Å; V103-Y106 HydrophobicContact CB-CE2 4.48Å; V103-Y106 HydrophobicContact CG1-CD2 3.79Å; V103-Y106 HydrophobicContact CG1-CE2 3.95Å; V103-Y106 PolarHBondContact O-N 3.35Å; V103-E184 HydrophobicContact CG1-CB 3.89Å; V103-V185 HydrophobicContact CG2-CG2 4.14Å; V103-T188 HydrophobicContact CG2-CG2 4.38Å
104	S	91.4	Very high	89.7	Confident	86 Å²	86	60.1 Å²	60.1	60%	0.601	33%	0.328	S	S	*	.	G	3₁₀ helix	trans	-66.1	-11	-176.9	62.1	0	0	0	0	114.8	Y106 T107 R108	S104-Y106 PolarHBondContact O-N 3.39Å; S104-T107 PolarHBondContact O-N 2.89Å; S104-T107 PolarHBondContact O-OG1 2.64Å; S104-R108 PolarHBondContact O-N 3.23Å
105	F	92.8	Very high	88.9	Confident	46 Å²	46	61.5 Å²	61.5	20%	0.202	33%	0.325	C	S	.	.	G	3₁₀ helix	trans	-56	-38.6	173	176.1	-96.3	0	0	0	112.3	V103 T107 R108 I180 E184 K239	V103-F105 HydrophobicContact CG1-CB 3.98Å; V103-F105 PolarHBondContact O-N 3.22Å; V103-F105 VanDerWaalsContact O-N 3.09Å; F105-T107 VanDerWaalsContact C-N 3.26Å; F105-T107 PolarHBondContact O-N 3.27Å; F105-R108 PolarHBondContact O-N 2.98Å; F105-I180 HydrophobicContact CE1-CG2 4.48Å; F105-E184 HydrophobicContact CB-CB 4.29Å; F105-E184 HydrophobicContact CB-CG 4.03Å; F105-E184 WeakPolarHBondContact CB-OE2 3.37Å; F105-E184 HydrophobicContact CD1-CB 4.49Å; F105-E184 HydrophobicContact CD1-CG 3.65Å; F105-E184 VanDerWaalsContact CD2-CD 3.49Å; F105-E184 HydrophobicContact CD2-CG 4.04Å; F105-E184 WeakPolarHBondContact CD2-OE2 3.28Å; F105-E184 HydrophobicContact CE1-CG 4.06Å; F105-E184 HydrophobicContact CE2-CG 4.42Å; F105-E184 HydrophobicContact CG-CB 4.4Å; F105-E184 HydrophobicContact CG-CG 3.63Å; F105-E184 WeakPolarHBondContact CG-OE2 3.28Å; F105-E184 HydrophobicContact CZ-CG 4.42Å; F105-K239 HydrophobicContact CD1-CD 4.41Å; F105-K239 HydrophobicContact CE1-CD 4.21Å; F105-K239 VanDerWaalsContact O-CD 3.27Å; F105-K239 WeakPolarHBondContact O-CD 3.25Å; F105-K239 WeakPolarHBondContact O-CE 3.25Å
106	Y	92.1	Very high	88.2	Confident	15 Å²	15	59.5 Å²	59.5	6%	0.059	31%	0.312	C	S	.	.	G	3₁₀ helix	trans	-72.9	-15.5	-176.3	-71.2	-75.9	0	0	0	114.1	T99 V103 S104 Y181 L235 K239	T99-Y106 HydrophobicContact CG2-CD2 3.62Å; T99-Y106 HydrophobicContact CG2-CE2 3.68Å; V103-Y106 HydrophobicContact CB-CD2 4.12Å; V103-Y106 HydrophobicContact CB-CE2 4.48Å; V103-Y106 HydrophobicContact CG1-CD2 3.79Å; V103-Y106 HydrophobicContact CG1-CE2 3.95Å; V103-Y106 PolarHBondContact O-N 3.35Å; S104-Y106 PolarHBondContact O-N 3.39Å; Y106-Y181 HydrophobicContact CE2-CD2 4.17Å; Y106-Y181 WeakPolarHBondContact OH-CD2 3.47Å; Y106-L235 HydrophobicContact CD1-CB 3.91Å; Y106-L235 HydrophobicContact CD1-CD2 4.07Å; Y106-L235 HydrophobicContact CD1-CG 4.49Å; Y106-L235 HydrophobicContact CD2-CD2 4.32Å; Y106-L235 HydrophobicContact CE1-CB 3.72Å; Y106-L235 HydrophobicContact CE1-CD1 4.46Å; Y106-L235 HydrophobicContact CE1-CD2 4.44Å; Y106-L235 HydrophobicContact CE1-CG 4.43Å; Y106-L235 HydrophobicContact CE2-CD1 4.48Å; Y106-L235 HydrophobicContact CG-CD2 4.02Å; Y106-K239 HydrophobicContact CD1-CB 4.08Å
107	T	90.2	Very high	87.7	Confident	67 Å²	67	63.4 Å²	63.4	41%	0.411	34%	0.338	S	S	.	.	G	3₁₀ helix	trans	-98	-13.5	176.4	60.9	0	0	0	0	112.8	I100 S104 F105 A340	I100-T107 HydrophobicContact CG2-CG2 3.9Å; S104-T107 PolarHBondContact O-N 2.89Å; S104-T107 PolarHBondContact O-OG1 2.64Å; F105-T107 VanDerWaalsContact C-N 3.26Å; F105-T107 PolarHBondContact O-N 3.27Å; T107-A340 HydrophobicContact CG2-CB 4.13Å
108	R	89	Confident	87.3	Confident	170 Å²	170	66.2 Å²	66.2	64%	0.642	35%	0.349	S	S	*	.	S	Bend	trans	-78.9	134.9	-177.4	-155.3	174.5	-176	-175.2	4.2	112.1	S104 F105 D110 K239	S104-R108 PolarHBondContact O-N 3.23Å; F105-R108 PolarHBondContact O-N 2.98Å; R108-D110 VanDerWaalsContact C-N 3.27Å; R108-D110 VanDerWaalsContact CD-OD2 3.31Å; R108-D110 WeakPolarHBondContact CD-OD2 3.31Å; R108-D110 IonicContact NE-OD1 2.92Å; R108-D110 IonicContact NE-OD2 3.86Å; R108-D110 PolarHBondContact O-N 3.12Å; R108-K239 WeakPolarHBondContact O-CE 3.29Å; R108-K239 PolarHBondContact O-NZ 3.02Å
109	K	83.1	Confident	86.8	Confident	146 Å²	146	66.5 Å²	66.5	64%	0.635	35%	0.345	S	S	*	.			trans	-83.7	58.9	-177.1	-63.3	-175.1	178.4	178.6	0	112.8	G111 E243	K109-G111 PolarHBondContact O-N 3.17Å; K109-E243 WeakPolarHBondContact CE-OE1 3.32Å; K109-E243 IonicContact NZ-OE1 3.51Å; K109-E243 PolarHBondContact NZ-OE1 3.26Å
110	D	75.5	Confident	86.1	Confident	84 Å²	84	66.8 Å²	66.8	45%	0.449	35%	0.347	S	S	.	.			trans	-93.3	73.5	178	-58.8	-30.8	0	0	0	111.4	R108 K239	R108-D110 VanDerWaalsContact C-N 3.27Å; R108-D110 VanDerWaalsContact CD-OD2 3.31Å; R108-D110 WeakPolarHBondContact CD-OD2 3.31Å; R108-D110 IonicContact NE-OD1 2.92Å; R108-D110 IonicContact NE-OD2 3.86Å; R108-D110 PolarHBondContact O-N 3.12Å; D110-K239 PolarHBondContact O-NZ 3.42Å
111	G	75.6	Confident	85.6	Confident	48 Å²	48	72.8 Å²	72.8	50%	0.495	38%	0.379	S	S	.	.			trans	92.5	165.3	178.8	0	0	0	0	0	115.3	K109	K109-G111 PolarHBondContact O-N 3.17Å
112	Q	76.3	Confident	85.3	Confident	75 Å²	75	71 Å²	71	35%	0.35	37%	0.374	S	S	.	.			trans	-121.3	157.9	-178.7	-69.9	175.8	-11.3	0	0	110.6	P242	Q112-P242 HydrophobicContact CG-CG 4.41Å
113	L	78.1	Confident	85	Confident	37 Å²	37	77.8 Å²	77.8	19%	0.194	40%	0.4	C	S	.	.			trans	-58.7	142.6	171.9	-87.8	140	0	0	0	110.4	Y115 T116 Y240 L241	L113-Y115 HydrophobicContact CD2-CD2 4.32Å; L113-Y115 PolarHBondContact O-N 3.44Å; L113-Y115 VanDerWaalsContact O-N 3.09Å; L113-T116 CarbonylContact O-C 3.51Å; L113-T116 PolarHBondContact O-N 3.39Å; L113-T116 PolarHBondContact O-OG1 3.41Å; L113-T116 VanDerWaalsContact O-OG1 3.08Å; L113-Y240 VanDerWaalsContact CG-CB 3.49Å; L113-Y240 HydrophobicContact CG-CG 4.36Å; L113-Y240 PolarHBondContact N-O 3.07Å; L113-L241 HydrophobicContact CD1-CD2 4.09Å; L113-L241 HydrophobicContact CD1-CG 3.9Å
114	I	80.5	Confident	84.9	Confident	150 Å²	150	81 Å²	81	77%	0.769	42%	0.419	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.8	-24.8	173.9	-163.8	165.8	0	0	0	112.7	T116	I114-T116 VanDerWaalsContact C-N 3.27Å; I114-T116 PolarHBondContact O-N 3.5Å
115	Y	80.2	Confident	85	Confident	115 Å²	115	82.5 Å²	82.5	45%	0.451	43%	0.425	S	S	.	.	T	Hydrogen-bonded Turn	trans	-79.1	-6.8	177.2	-61.7	-69.3	0	0	0	113.9	L113 I138 V142	L113-Y115 HydrophobicContact CD2-CD2 4.32Å; L113-Y115 PolarHBondContact O-N 3.44Å; L113-Y115 VanDerWaalsContact O-N 3.09Å; Y115-I138 WeakPolarHBondContact O-CG2 3.34Å; Y115-V142 HydrophobicContact CD1-CG1 4.41Å; Y115-V142 HydrophobicContact CD1-CG2 3.97Å; Y115-V142 HydrophobicContact CE1-CG1 4.06Å; Y115-V142 HydrophobicContact CE1-CG2 4.15Å
116	T	84	Confident	85.1	Confident	0 Å²	0	82.5 Å²	82.5	0%	0	44%	0.437	C	S	.	.			trans	-126.6	74.3	176.9	57.1	0	0	0	0	109.2	L113 I114 F118 N135 L241 T245	L113-T116 CarbonylContact O-C 3.51Å; L113-T116 PolarHBondContact O-N 3.39Å; L113-T116 PolarHBondContact O-OG1 3.41Å; L113-T116 VanDerWaalsContact O-OG1 3.08Å; I114-T116 VanDerWaalsContact C-N 3.27Å; I114-T116 PolarHBondContact O-N 3.5Å; T116-F118 VanDerWaalsContact C-N 3.29Å; T116-F118 PolarHBondContact O-N 2.83Å; T116-N135 VanDerWaalsContact C-OD1 3.25Å; T116-N135 VanDerWaalsContact CA-OD1 3.31Å; T116-N135 WeakPolarHBondContact CA-OD1 3.42Å; T116-N135 HydrophobicContact CG2-CB 3.96Å; T116-L241 HydrophobicContact CG2-CD2 4.13Å; T116-T245 HydrophobicContact CG2-CG2 4.13Å
117	P	86.9	Confident	85.2	Confident	82 Å²	82	86.3 Å²	86.3	53%	0.532	46%	0.456	S	S	.	.			trans	-75.6	-14.4	-171.3	30.9	-36.3	0	0	0	113.9	I138	P117-I138 HydrophobicContact CG-CD1 4.25Å
118	F	87.4	Confident	85.3	Confident	74 Å²	74	86.3 Å²	86.3	33%	0.325	45%	0.448	S	S	.	.	S	Bend	trans	-92.1	120.4	-176.7	-59.1	-74.2	0	0	0	110.9	T116 H131 L134 N135 I138	T116-F118 VanDerWaalsContact C-N 3.29Å; T116-F118 PolarHBondContact O-N 2.83Å; F118-H131 HydrophobicContact CB-CB 3.81Å; F118-L134 HydrophobicContact CD2-CB 3.78Å; F118-L134 HydrophobicContact CD2-CD1 4.42Å; F118-L134 HydrophobicContact CE2-CB 3.83Å; F118-L134 HydrophobicContact CE2-CD1 4.17Å; F118-L134 HydrophobicContact CZ-CD1 4.3Å; F118-N135 WeakPolarHBondContact CB-OD1 3.4Å; F118-N135 WeakPolarHBondContact CD2-OD1 3.25Å; F118-N135 PolarHBondContact N-OD1 2.84Å; F118-N135 PolarHBondContact O-ND2 3.35Å; F118-I138 HydrophobicContact CD2-CD1 4.41Å; F118-I138 HydrophobicContact CE2-CD1 3.82Å
119	T	85.6	Confident	85.6	Confident	57 Å²	57	79.7 Å²	79.7	35%	0.35	43%	0.43	S	S	.	.			trans	-71.3	144.6	175.7	-175.8	0	0	0	0	112	D121 H131	T119-D121 PolarHBondContact OG1-N 2.94Å; T119-H131 PolarHBondContact O-ND1 3.35Å
120	E	82.6	Confident	86.2	Confident	10 Å²	10	77.4 Å²	77.4	5%	0.047	43%	0.425	C	S	.	.	S	Bend	trans	-87.1	-5.5	174.8	-70.1	-169	177.3	0	0	113.2	T122 R128 S132 P242 W244 T245	E120-T122 PolarHBondContact O-N 3.27Å; E120-R128 HydrophobicContact CB-CG 4.11Å; E120-R128 HydrophobicContact CG-CG 4.44Å; E120-R128 IonicContact OE2-NE 3.65Å; E120-R128 IonicContact OE2-NH2 3.98Å; E120-S132 PolarHBondContact OE1-OG 3.29Å; E120-P242 HydrophobicContact CG-CB 3.76Å; E120-P242 HydrophobicContact CG-CG 4.41Å; E120-P242 VanDerWaalsContact OE1-CB 3.31Å; E120-P242 WeakPolarHBondContact OE1-CB 3.31Å; E120-W244 WeakPolarHBondContact OE1-CB 3.01Å; E120-W244 PolarHBondContact OE2-N 3.3Å; E120-T245 WeakPolarHBondContact OE1-CB 3.38Å; E120-T245 PolarHBondContact OE1-N 2.91Å; E120-T245 PolarHBondContact OE1-OG1 3.25Å
121	D	84	Confident	87	Confident	133 Å²	133	75.4 Å²	75.4	71%	0.711	41%	0.412	S	S	*	.			trans	-80.1	66.2	-179.2	-58.6	-37.4	0	0	0	110.9	T119	T119-D121 PolarHBondContact OG1-N 2.94Å
122	T	87.7	Confident	87.9	Confident	38 Å²	38	73.1 Å²	73.1	23%	0.233	39%	0.389	C	S	.	.			trans	-116.7	149.8	179.1	55.3	0	0	0	0	111.1	E120 T124 Q127 R128	E120-T122 PolarHBondContact O-N 3.27Å; T122-T124 VanDerWaalsContact C-N 3.31Å; T122-T124 PolarHBondContact O-N 2.9Å; T122-Q127 HydrophobicContact CG2-CB 4.27Å; T122-R128 WeakPolarHBondContact OG1-CA 3.41Å; T122-R128 PolarHBondContact OG1-N 3.38Å; T122-R128 VanDerWaalsContact OG1-N 3.07Å
123	E	86.5	Confident	88.8	Confident	200 Å²	200	74.4 Å²	74.4	94%	0.935	40%	0.397	S	S	*	.	S	Bend	trans	-68.2	-28.6	-174.2	-62.9	-176.7	172.9	0	0	113.3
124	T	93.4	Very high	89.6	Confident	68 Å²	68	75.8 Å²	75.8	42%	0.417	40%	0.404	S	S	.	.	S	Bend	trans	-108.8	136.3	-175.9	65.8	0	0	0	0	112	T122 G126 Q127 R128	T122-T124 VanDerWaalsContact C-N 3.31Å; T122-T124 PolarHBondContact O-N 2.9Å; T124-G126 PolarHBondContact O-N 2.9Å; T124-Q127 PolarHBondContact O-N 3.19Å; T124-Q127 VanDerWaalsContact O-N 3.15Å; T124-Q127 VanDerWaalsContact OG1-CB 3.31Å; T124-Q127 WeakPolarHBondContact OG1-CB 3.49Å; T124-Q127 VanDerWaalsContact OG1-CD 3.27Å; T124-Q127 WeakPolarHBondContact OG1-CG 3.11Å; T124-Q127 PolarHBondContact OG1-N 2.88Å; T124-Q127 PolarHBondContact OG1-OE1 2.91Å; T124-R128 PolarHBondContact O-N 2.94Å
125	V	94	Very high	90.2	Very high	117 Å²	117	68.7 Å²	68.7	71%	0.709	37%	0.368	S	S	*	.	H	α-helix	trans	-57.4	-32.2	175.9	-64.6	0	0	0	0	112.5	R128 A129	V125-R128 PolarHBondContact O-N 3.12Å; V125-A129 WeakPolarHBondContact O-CB 3.23Å; V125-A129 PolarHBondContact O-N 3.49Å
126	G	94.1	Very high	90.9	Very high	46 Å²	46	63.4 Å²	63.4	47%	0.474	35%	0.348	S	S	.	.	H	α-helix	trans	-66.9	-43.6	177.5	0	0	0	0	0	112.8	T124 A129 L130	T124-G126 PolarHBondContact O-N 2.9Å; G126-A129 PolarHBondContact O-N 3.08Å; G126-L130 WeakPolarHBondContact O-CB 3.4Å; G126-L130 PolarHBondContact O-N 3.35Å
127	Q	93.5	Very high	91.4	Very high	96 Å²	96	66.1 Å²	66.1	45%	0.449	37%	0.37	S	S	.	.	H	α-helix	trans	-66.8	-42.1	174.8	-74.8	173.1	-35.5	0	0	111.4	T122 T124 A129 L130 H131	T122-Q127 HydrophobicContact CG2-CB 4.27Å; T124-Q127 PolarHBondContact O-N 3.19Å; T124-Q127 VanDerWaalsContact O-N 3.15Å; T124-Q127 VanDerWaalsContact OG1-CB 3.31Å; T124-Q127 WeakPolarHBondContact OG1-CB 3.49Å; T124-Q127 VanDerWaalsContact OG1-CD 3.27Å; T124-Q127 WeakPolarHBondContact OG1-CG 3.11Å; T124-Q127 PolarHBondContact OG1-N 2.88Å; T124-Q127 PolarHBondContact OG1-OE1 2.91Å; Q127-A129 PolarHBondContact O-N 3.43Å; Q127-L130 PolarHBondContact O-N 3.33Å; Q127-H131 WeakPolarHBondContact O-CB 3.26Å; Q127-H131 PolarHBondContact O-CD2 2.97Å; Q127-H131 VanDerWaalsContact O-CG 3.32Å; Q127-H131 PolarHBondContact O-N 3.24Å
128	R	93.5	Very high	91.7	Very high	66 Å²	66	65 Å²	65	25%	0.249	36%	0.36	C	S	.	.	H	α-helix	trans	-57.4	-50	175.1	-174.6	173.7	-179.9	-179.6	1.9	111.1	E120 T122 T124 V125 L130 H131 S132 E243 W244	E120-R128 HydrophobicContact CB-CG 4.11Å; E120-R128 HydrophobicContact CG-CG 4.44Å; E120-R128 IonicContact OE2-NE 3.65Å; E120-R128 IonicContact OE2-NH2 3.98Å; T122-R128 WeakPolarHBondContact OG1-CA 3.41Å; T122-R128 PolarHBondContact OG1-N 3.38Å; T122-R128 VanDerWaalsContact OG1-N 3.07Å; T124-R128 PolarHBondContact O-N 2.94Å; V125-R128 PolarHBondContact O-N 3.12Å; R128-L130 PolarHBondContact O-N 2.95Å; R128-H131 PolarHBondContact O-N 2.8Å; R128-S132 WeakPolarHBondContact O-CB 3.45Å; R128-S132 PolarHBondContact O-N 3.45Å; R128-S132 PolarHBondContact O-OG 2.8Å; R128-E243 IonicContact NH2-OE2 3.92Å; R128-W244 VanDerWaalsContact NH2-CD1 3.26Å
129	A	94.8	Very high	92	Very high	32 Å²	32	62 Å²	62	26%	0.264	35%	0.347	S	S	.	.	H	α-helix	trans	-59.9	-43.6	177.7	0	0	0	0	0	112.3	V125 G126 Q127 S132 I133 W244	V125-A129 WeakPolarHBondContact O-CB 3.23Å; V125-A129 PolarHBondContact O-N 3.49Å; G126-A129 PolarHBondContact O-N 3.08Å; Q127-A129 PolarHBondContact O-N 3.43Å; A129-S132 PolarHBondContact O-N 3.05Å; A129-I133 WeakPolarHBondContact O-CB 3.42Å; A129-I133 VanDerWaalsContact O-CG1 3.25Å; A129-I133 WeakPolarHBondContact O-CG1 3.18Å; A129-I133 PolarHBondContact O-N 3.27Å; A129-W244 HydrophobicContact CB-CZ3 4.17Å
130	L	95.1	Very high	92.4	Very high	98 Å²	98	60.3 Å²	60.3	51%	0.513	34%	0.335	S	S	.	.	H	α-helix	trans	-61.1	-47.1	177.1	-177.6	67	0	0	0	111.6	G126 Q127 R128 I133 L134	G126-L130 WeakPolarHBondContact O-CB 3.4Å; G126-L130 PolarHBondContact O-N 3.35Å; Q127-L130 PolarHBondContact O-N 3.33Å; R128-L130 PolarHBondContact O-N 2.95Å; L130-I133 PolarHBondContact O-N 3.48Å; L130-L134 HydrophobicContact CD1-CD1 4.49Å; L130-L134 HydrophobicContact CG-CD1 4.13Å; L130-L134 WeakPolarHBondContact O-CB 2.87Å; L130-L134 VanDerWaalsContact O-CG 3.29Å; L130-L134 WeakPolarHBondContact O-CG 3.37Å; L130-L134 PolarHBondContact O-N 2.81Å
131	H	93.7	Very high	92.9	Very high	42 Å²	42	62.7 Å²	62.7	19%	0.194	35%	0.353	C	S	.	.	H	α-helix	trans	-62.7	-43	177.9	-71.8	-169.7	0	0	0	111.7	F118 T119 Q127 R128 I133 L134 N135	F118-H131 HydrophobicContact CB-CB 3.81Å; T119-H131 PolarHBondContact O-ND1 3.35Å; Q127-H131 WeakPolarHBondContact O-CB 3.26Å; Q127-H131 PolarHBondContact O-CD2 2.97Å; Q127-H131 VanDerWaalsContact O-CG 3.32Å; Q127-H131 PolarHBondContact O-N 3.24Å; R128-H131 PolarHBondContact O-N 2.8Å; H131-I133 PolarHBondContact O-N 3.46Å; H131-L134 PolarHBondContact O-N 3.33Å; H131-N135 WeakPolarHBondContact O-CB 3.17Å; H131-N135 VanDerWaalsContact O-CG 3.31Å; H131-N135 PolarHBondContact O-N 3.45Å; H131-N135 PolarHBondContact O-ND2 3.05Å
132	S	93.7	Very high	93.4	Very high	0 Å²	0	58.2 Å²	58.2	0%	0	33%	0.33	C	S	.	.	H	α-helix	trans	-62.6	-41.6	176.3	-57.3	0	0	0	0	112.4	E120 R128 A129 A136 W244 T245	E120-S132 PolarHBondContact OE1-OG 3.29Å; R128-S132 WeakPolarHBondContact O-CB 3.45Å; R128-S132 PolarHBondContact O-N 3.45Å; R128-S132 PolarHBondContact O-OG 2.8Å; A129-S132 PolarHBondContact O-N 3.05Å; S132-A136 WeakPolarHBondContact O-CB 3.38Å; S132-A136 PolarHBondContact O-N 2.79Å; S132-W244 VanDerWaalsContact OG-CB 3.3Å; S132-W244 WeakPolarHBondContact OG-CB 3.5Å; S132-T245 WeakPolarHBondContact CA-OG1 2.92Å
133	I	95.6	Very high	93.6	Very high	101 Å²	101	58.4 Å²	58.4	52%	0.518	33%	0.329	S	S	.	.	H	α-helix	trans	-64.9	-44.2	175.8	-69.9	166.7	0	0	0	110.7	A129 L130 H131 A136 A137 L248	A129-I133 WeakPolarHBondContact O-CB 3.42Å; A129-I133 VanDerWaalsContact O-CG1 3.25Å; A129-I133 WeakPolarHBondContact O-CG1 3.18Å; A129-I133 PolarHBondContact O-N 3.27Å; L130-I133 PolarHBondContact O-N 3.48Å; H131-I133 PolarHBondContact O-N 3.46Å; I133-A136 PolarHBondContact O-N 3.27Å; I133-A137 WeakPolarHBondContact O-CB 3.3Å; I133-A137 PolarHBondContact O-N 3.47Å; I133-L248 HydrophobicContact CG1-CD1 3.86Å
134	L	94.5	Very high	94	Very high	67 Å²	67	50.6 Å²	50.6	35%	0.351	30%	0.295	S	S	.	.	H	α-helix	trans	-62.6	-45.5	178	-73	170.9	0	0	0	111.8	F118 L130 H131 A137 I138	F118-L134 HydrophobicContact CD2-CB 3.78Å; F118-L134 HydrophobicContact CD2-CD1 4.42Å; F118-L134 HydrophobicContact CE2-CB 3.83Å; F118-L134 HydrophobicContact CE2-CD1 4.17Å; F118-L134 HydrophobicContact CZ-CD1 4.3Å; L130-L134 HydrophobicContact CD1-CD1 4.49Å; L130-L134 HydrophobicContact CG-CD1 4.13Å; L130-L134 WeakPolarHBondContact O-CB 2.87Å; L130-L134 VanDerWaalsContact O-CG 3.29Å; L130-L134 WeakPolarHBondContact O-CG 3.37Å; L130-L134 PolarHBondContact O-N 2.81Å; H131-L134 PolarHBondContact O-N 3.33Å; L134-A137 PolarHBondContact O-N 3.49Å; L134-I138 WeakPolarHBondContact O-CG1 3.33Å; L134-I138 PolarHBondContact O-N 2.64Å
135	N	93.9	Very high	94.1	Very high	0 Å²	0	51.7 Å²	51.7	0%	0	30%	0.302	C	S	.	.	H	α-helix	trans	-59.4	-47.5	174.7	-76.5	-25.7	0	0	0	111.9	T116 F118 H131 A137 I138 M139 T245	T116-N135 VanDerWaalsContact C-OD1 3.25Å; T116-N135 VanDerWaalsContact CA-OD1 3.31Å; T116-N135 WeakPolarHBondContact CA-OD1 3.42Å; T116-N135 HydrophobicContact CG2-CB 3.96Å; F118-N135 WeakPolarHBondContact CB-OD1 3.4Å; F118-N135 WeakPolarHBondContact CD2-OD1 3.25Å; F118-N135 PolarHBondContact N-OD1 2.84Å; F118-N135 PolarHBondContact O-ND2 3.35Å; H131-N135 WeakPolarHBondContact O-CB 3.17Å; H131-N135 VanDerWaalsContact O-CG 3.31Å; H131-N135 PolarHBondContact O-N 3.45Å; H131-N135 PolarHBondContact O-ND2 3.05Å; N135-A137 VanDerWaalsContact C-N 3.34Å; N135-A137 PolarHBondContact O-N 3.39Å; N135-I138 PolarHBondContact O-N 3.44Å; N135-M139 WeakPolarHBondContact O-CB 3.33Å; N135-M139 PolarHBondContact O-N 3.01Å; N135-T245 HydrophobicContact CB-CG2 3.6Å
136	A	93.6	Very high	94	Very high	5 Å²	5	49.9 Å²	49.9	4%	0.041	29%	0.286	C	S	.	.	H	α-helix	trans	-61.3	-42.6	177.9	0	0	0	0	0	111.3	S132 I133 M139 I140 L248 I249	S132-A136 WeakPolarHBondContact O-CB 3.38Å; S132-A136 PolarHBondContact O-N 2.79Å; I133-A136 PolarHBondContact O-N 3.27Å; A136-M139 PolarHBondContact O-N 3.28Å; A136-I140 WeakPolarHBondContact O-CB 3.15Å; A136-I140 WeakPolarHBondContact O-CG1 3.46Å; A136-I140 PolarHBondContact O-N 2.86Å; A136-L248 HydrophobicContact CB-CB 3.99Å; A136-I249 HydrophobicContact CB-CG1 4Å
137	A	95	Very high	93.9	Very high	56 Å²	56	49.1 Å²	49.1	46%	0.463	27%	0.273	S	S	.	.	H	α-helix	trans	-63	-45.5	178	0	0	0	0	0	112.5	I133 L134 N135 S141	I133-A137 WeakPolarHBondContact O-CB 3.3Å; I133-A137 PolarHBondContact O-N 3.47Å; L134-A137 PolarHBondContact O-N 3.49Å; N135-A137 VanDerWaalsContact C-N 3.34Å; N135-A137 PolarHBondContact O-N 3.39Å; A137-S141 WeakPolarHBondContact O-CB 3.35Å; A137-S141 PolarHBondContact O-N 3.47Å
138	I	94.5	Very high	93.9	Very high	60 Å²	60	48.5 Å²	48.5	31%	0.308	27%	0.272	S	S	.	.	H	α-helix	trans	-61.8	-48.9	177.1	-67.7	166.4	0	0	0	110.1	Y115 P117 F118 L134 N135 I140 S141 V142	Y115-I138 WeakPolarHBondContact O-CG2 3.34Å; P117-I138 HydrophobicContact CG-CD1 4.25Å; F118-I138 HydrophobicContact CD2-CD1 4.41Å; F118-I138 HydrophobicContact CE2-CD1 3.82Å; L134-I138 WeakPolarHBondContact O-CG1 3.33Å; L134-I138 PolarHBondContact O-N 2.64Å; N135-I138 PolarHBondContact O-N 3.44Å; I138-I140 PolarHBondContact O-N 3.12Å; I138-S141 PolarHBondContact O-N 2.71Å; I138-S141 PolarHBondContact O-OG 3.49Å; I138-V142 PolarHBondContact O-N 2.97Å; I138-V142 VanDerWaalsContact O-N 3.12Å
139	M	92.9	Very high	93.9	Very high	11 Å²	11	49.3 Å²	49.3	5%	0.054	28%	0.28	C	S	.	.	H	α-helix	trans	-63.8	-44.5	-178.5	179.8	160.3	162.2	0	0	112.5	N135 A136 S141 V142 I143 F237 L241 I249	N135-M139 WeakPolarHBondContact O-CB 3.33Å; N135-M139 PolarHBondContact O-N 3.01Å; A136-M139 PolarHBondContact O-N 3.28Å; M139-S141 VanDerWaalsContact C-N 3.32Å; M139-S141 PolarHBondContact O-N 2.96Å; M139-V142 PolarHBondContact O-N 3.2Å; M139-I143 HydrophobicContact CE-CD1 4.22Å; M139-I143 HydrophobicContact CG-CD1 4.2Å; M139-I143 WeakPolarHBondContact O-CG1 3.34Å; M139-I143 PolarHBondContact O-N 3.41Å; M139-I143 VanDerWaalsContact O-N 3.1Å; M139-F237 HydrophobicContact CE-CD1 3.88Å; M139-F237 HydrophobicContact CE-CE1 3.34Å; M139-F237 HydrophobicContact CE-CZ 4.21Å; M139-L241 HydrophobicContact CE-CD1 4.38Å; M139-L241 HydrophobicContact CE-CD2 4.38Å; M139-L241 HydrophobicContact SD-CD2 3.74Å; M139-I249 HydrophobicContact CB-CD1 4.33Å; M139-I249 HydrophobicContact CE-CD1 4.04Å; M139-I249 HydrophobicContact CE-CG2 4.28Å; M139-I249 HydrophobicContact CG-CD1 4.2Å; M139-I249 HydrophobicContact SD-CD1 3.4Å; M139-I249 WeakPolarHBondContact SD-CD1 3.29Å; M139-I249 HydrophobicContact SD-CG1 4.42Å
140	I	92.9	Very high	93.7	Very high	21 Å²	21	48.8 Å²	48.8	11%	0.108	27%	0.273	C	S	.	.	H	α-helix	trans	-62.4	-40.7	175.5	-67.1	-69.5	0	0	0	110.5	A136 I138 V142 I143 V144 I249 V252 I253	A136-I140 WeakPolarHBondContact O-CB 3.15Å; A136-I140 WeakPolarHBondContact O-CG1 3.46Å; A136-I140 PolarHBondContact O-N 2.86Å; I138-I140 PolarHBondContact O-N 3.12Å; I140-V142 VanDerWaalsContact C-N 3.29Å; I140-V142 PolarHBondContact O-N 3.01Å; I140-I143 PolarHBondContact O-N 3.13Å; I140-V144 HydrophobicContact CG2-CG2 4.09Å; I140-V144 VanDerWaalsContact O-CG2 3.25Å; I140-V144 WeakPolarHBondContact O-CG2 3.1Å; I140-V144 PolarHBondContact O-N 3.49Å; I140-I249 HydrophobicContact CD1-CG2 4.48Å; I140-V252 HydrophobicContact CD1-CB 4.34Å; I140-V252 HydrophobicContact CD1-CG1 4Å; I140-V252 HydrophobicContact CG1-CB 4.32Å; I140-V252 HydrophobicContact CG1-CG1 3.81Å; I140-V252 HydrophobicContact CG2-CG1 4.16Å; I140-I253 HydrophobicContact CD1-CB 4.14Å; I140-I253 HydrophobicContact CD1-CG1 4.39Å
141	S	94.3	Very high	93.5	Very high	60 Å²	60	44.7 Å²	44.7	42%	0.42	25%	0.252	S	S	.	.	H	α-helix	trans	-58	-41.3	176.8	79	0	0	0	0	112.4	A137 I138 M139 V144 V145	A137-S141 WeakPolarHBondContact O-CB 3.35Å; A137-S141 PolarHBondContact O-N 3.47Å; I138-S141 PolarHBondContact O-N 2.71Å; I138-S141 PolarHBondContact O-OG 3.49Å; M139-S141 VanDerWaalsContact C-N 3.32Å; M139-S141 PolarHBondContact O-N 2.96Å; S141-V144 PolarHBondContact O-N 3.32Å; S141-V145 WeakPolarHBondContact O-CB 3.38Å; S141-V145 VanDerWaalsContact O-CG2 3.24Å; S141-V145 WeakPolarHBondContact O-CG2 3.31Å; S141-V145 PolarHBondContact O-N 3.23Å
142	V	94.5	Very high	93.4	Very high	38 Å²	38	45.5 Å²	45.5	23%	0.23	26%	0.26	C	S	.	.	H	α-helix	trans	-66	-44.3	176.8	175.7	0	0	0	0	111	Y115 I138 M139 I140 V144 V145 M146	Y115-V142 HydrophobicContact CD1-CG1 4.41Å; Y115-V142 HydrophobicContact CD1-CG2 3.97Å; Y115-V142 HydrophobicContact CE1-CG1 4.06Å; Y115-V142 HydrophobicContact CE1-CG2 4.15Å; I138-V142 PolarHBondContact O-N 2.97Å; I138-V142 VanDerWaalsContact O-N 3.12Å; M139-V142 PolarHBondContact O-N 3.2Å; I140-V142 VanDerWaalsContact C-N 3.29Å; I140-V142 PolarHBondContact O-N 3.01Å; V142-V144 VanDerWaalsContact C-N 3.34Å; V142-V144 PolarHBondContact O-N 2.88Å; V142-V145 PolarHBondContact O-N 3.38Å; V142-M146 HydrophobicContact CG1-CE 4.5Å; V142-M146 HydrophobicContact CG1-CG 4.22Å; V142-M146 WeakPolarHBondContact O-CB 3.22Å; V142-M146 WeakPolarHBondContact O-CG 3.06Å; V142-M146 PolarHBondContact O-N 2.98Å
143	I	92.6	Very high	93.4	Very high	43 Å²	43	47 Å²	47	22%	0.221	27%	0.268	C	S	.	.	H	α-helix	trans	-60.4	-44.2	177.4	-66.8	168.9	0	0	0	110.9	M139 I140 M146 T147 I253	M139-I143 HydrophobicContact CE-CD1 4.22Å; M139-I143 HydrophobicContact CG-CD1 4.2Å; M139-I143 WeakPolarHBondContact O-CG1 3.34Å; M139-I143 PolarHBondContact O-N 3.41Å; M139-I143 VanDerWaalsContact O-N 3.1Å; I140-I143 PolarHBondContact O-N 3.13Å; I143-M146 PolarHBondContact O-N 3.04Å; I143-T147 WeakPolarHBondContact O-CB 3.16Å; I143-T147 PolarHBondContact O-N 3.23Å; I143-T147 PolarHBondContact O-OG1 3.45Å; I143-I253 HydrophobicContact CD1-CD1 4.33Å
144	V	93.4	Very high	93.1	Very high	36 Å²	36	42.5 Å²	42.5	22%	0.218	24%	0.244	C	C	.	.	H	α-helix	trans	-63.8	-48.3	178.6	174.9	0	0	0	0	110.7	I140 S141 V142 M146 T147 I148 Y256	I140-V144 HydrophobicContact CG2-CG2 4.09Å; I140-V144 VanDerWaalsContact O-CG2 3.25Å; I140-V144 WeakPolarHBondContact O-CG2 3.1Å; I140-V144 PolarHBondContact O-N 3.49Å; S141-V144 PolarHBondContact O-N 3.32Å; V142-V144 VanDerWaalsContact C-N 3.34Å; V142-V144 PolarHBondContact O-N 2.88Å; V144-M146 VanDerWaalsContact C-N 3.35Å; V144-M146 PolarHBondContact O-N 3.3Å; V144-T147 PolarHBondContact O-N 3.44Å; V144-I148 HydrophobicContact CG1-CD1 3.79Å; V144-I148 HydrophobicContact CG1-CG1 4.45Å; V144-I148 WeakPolarHBondContact O-CG1 3.49Å; V144-I148 PolarHBondContact O-N 2.87Å; V144-Y256 HydrophobicContact CG1-CE2 4.34Å; V144-Y256 HydrophobicContact CG2-CD2 4.02Å; V144-Y256 HydrophobicContact CG2-CE1 4.35Å; V144-Y256 HydrophobicContact CG2-CE2 3.56Å
145	V	95.2	Very high	92.9	Very high	91 Å²	91	45 Å²	45	55%	0.552	25%	0.252	S	S	*	.	H	α-helix	trans	-60.6	-44.2	178.6	170.2	0	0	0	0	111.2	S141 V142 T147 I148 L149	S141-V145 WeakPolarHBondContact O-CB 3.38Å; S141-V145 VanDerWaalsContact O-CG2 3.24Å; S141-V145 WeakPolarHBondContact O-CG2 3.31Å; S141-V145 PolarHBondContact O-N 3.23Å; V142-V145 PolarHBondContact O-N 3.38Å; V145-T147 PolarHBondContact O-N 3.36Å; V145-I148 PolarHBondContact O-N 2.9Å; V145-L149 WeakPolarHBondContact O-CB 3.09Å; V145-L149 PolarHBondContact O-N 2.92Å
146	M	92.4	Very high	92.7	Very high	79 Å²	79	53.3 Å²	53.3	39%	0.389	29%	0.285	S	S	.	.	H	α-helix	trans	-65.7	-38.2	177.9	-69.3	-67.1	167.4	0	0	112.1	V142 I143 V144 L149 L150	V142-M146 HydrophobicContact CG1-CE 4.5Å; V142-M146 HydrophobicContact CG1-CG 4.22Å; V142-M146 WeakPolarHBondContact O-CB 3.22Å; V142-M146 WeakPolarHBondContact O-CG 3.06Å; V142-M146 PolarHBondContact O-N 2.98Å; I143-M146 PolarHBondContact O-N 3.04Å; V144-M146 VanDerWaalsContact C-N 3.35Å; V144-M146 PolarHBondContact O-N 3.3Å; M146-L149 PolarHBondContact O-N 3.03Å; M146-L149 HydrophobicContact SD-CD2 4.49Å; M146-L150 WeakPolarHBondContact O-CB 3.45Å; M146-L150 PolarHBondContact O-N 3.47Å
147	T	91.9	Very high	92.5	Very high	30 Å²	30	61.1 Å²	61.1	18%	0.184	31%	0.313	C	S	.	.	H	α-helix	trans	-65	-46.6	175.9	-57.3	0	0	0	0	110.8	I143 V144 V145 L149 L150 V151 P267 L268	I143-T147 WeakPolarHBondContact O-CB 3.16Å; I143-T147 PolarHBondContact O-N 3.23Å; I143-T147 PolarHBondContact O-OG1 3.45Å; V144-T147 PolarHBondContact O-N 3.44Å; V145-T147 PolarHBondContact O-N 3.36Å; T147-L149 PolarHBondContact O-N 2.81Å; T147-L150 PolarHBondContact O-N 3.48Å; T147-V151 VanDerWaalsContact O-CG2 3.3Å; T147-V151 WeakPolarHBondContact O-CG2 3.35Å; T147-V151 PolarHBondContact O-N 3.23Å; T147-P267 HydrophobicContact CG2-CB 4.17Å; T147-P267 HydrophobicContact CG2-CG 4.23Å; T147-L268 HydrophobicContact CG2-CD2 4.23Å; T147-L268 HydrophobicContact CG2-CG 4.46Å
148	I	92.8	Very high	92.3	Very high	83 Å²	83	60.8 Å²	60.8	43%	0.426	31%	0.307	S	S	.	.	H	α-helix	trans	-62.7	-43.4	176.6	-67.1	169.5	0	0	0	110.5	V144 V145 L150 V151 V152	V144-I148 HydrophobicContact CG1-CD1 3.79Å; V144-I148 HydrophobicContact CG1-CG1 4.45Å; V144-I148 WeakPolarHBondContact O-CG1 3.49Å; V144-I148 PolarHBondContact O-N 2.87Å; V145-I148 PolarHBondContact O-N 2.9Å; I148-L150 VanDerWaalsContact C-N 3.33Å; I148-L150 PolarHBondContact O-N 3.49Å; I148-V151 PolarHBondContact O-N 2.91Å; I148-V152 HydrophobicContact CG2-CG2 4.12Å; I148-V152 WeakPolarHBondContact O-CB 3.29Å; I148-V152 VanDerWaalsContact O-CG2 3.23Å; I148-V152 WeakPolarHBondContact O-CG2 3.28Å; I148-V152 PolarHBondContact O-N 3.05Å
149	L	94	Very high	92	Very high	82 Å²	82	60.7 Å²	60.7	43%	0.429	30%	0.303	S	S	.	.	H	α-helix	trans	-58.9	-43.9	177	-177.9	64.5	0	0	0	111.5	V145 M146 T147 V152 L153	V145-L149 WeakPolarHBondContact O-CB 3.09Å; V145-L149 PolarHBondContact O-N 2.92Å; M146-L149 PolarHBondContact O-N 3.03Å; M146-L149 HydrophobicContact SD-CD2 4.49Å; T147-L149 PolarHBondContact O-N 2.81Å; L149-V152 PolarHBondContact O-N 3.43Å; L149-L153 HydrophobicContact CD1-CD1 4.39Å; L149-L153 HydrophobicContact CD1-CG 4.39Å; L149-L153 HydrophobicContact CG-CD1 4.13Å; L149-L153 WeakPolarHBondContact O-CB 3.39Å; L149-L153 VanDerWaalsContact O-CG 3.27Å; L149-L153 WeakPolarHBondContact O-CG 3.49Å; L149-L153 PolarHBondContact O-N 2.84Å
150	L	90.8	Very high	92	Very high	22 Å²	22	69.2 Å²	69.2	12%	0.115	34%	0.34	C	S	.	.	H	α-helix	trans	-59.8	-48.1	175.7	-166.7	162.9	0	0	0	111	M146 T147 I148 V152 L153 Y154 W165 L271 F283	M146-L150 WeakPolarHBondContact O-CB 3.45Å; M146-L150 PolarHBondContact O-N 3.47Å; T147-L150 PolarHBondContact O-N 3.48Å; I148-L150 VanDerWaalsContact C-N 3.33Å; I148-L150 PolarHBondContact O-N 3.49Å; L150-V152 PolarHBondContact O-N 3.09Å; L150-L153 PolarHBondContact O-N 2.96Å; L150-Y154 WeakPolarHBondContact O-CB 3.27Å; L150-Y154 PolarHBondContact O-N 3.38Å; L150-W165 HydrophobicContact CB-CH2 4.42Å; L150-W165 HydrophobicContact CB-CZ3 3.89Å; L150-W165 HydrophobicContact CD1-CH2 4.09Å; L150-W165 HydrophobicContact CD1-CZ3 3.67Å; L150-W165 HydrophobicContact CG-CZ3 3.85Å; L150-L271 HydrophobicContact CD2-CD1 3.5Å; L150-L271 VanDerWaalsContact CD2-CD1 3.5Å; L150-F283 HydrophobicContact CD2-CE2 4.38Å
151	V	90.8	Very high	92	Very high	11 Å²	11	71.9 Å²	71.9	7%	0.067	36%	0.357	C	S	.	.	H	α-helix	trans	-61.8	-43.3	178.9	174.5	0	0	0	0	111.4	T147 I148 Y154 K155 P267 M270 L271	T147-V151 VanDerWaalsContact O-CG2 3.3Å; T147-V151 WeakPolarHBondContact O-CG2 3.35Å; T147-V151 PolarHBondContact O-N 3.23Å; I148-V151 PolarHBondContact O-N 2.91Å; V151-Y154 PolarHBondContact O-N 2.94Å; V151-K155 WeakPolarHBondContact O-CB 3.35Å; V151-K155 PolarHBondContact O-N 3.16Å; V151-P267 HydrophobicContact CG2-CB 3.9Å; V151-P267 VanDerWaalsContact CG2-O 3.24Å; V151-P267 WeakPolarHBondContact CG2-O 3.41Å; V151-M270 HydrophobicContact CG1-CB 4.36Å; V151-M270 HydrophobicContact CG1-CG 4.31Å; V151-M270 HydrophobicContact CG1-SD 3.95Å; V151-L271 HydrophobicContact CG2-CB 4.27Å; V151-L271 HydrophobicContact CG2-CD1 4.1Å
152	V	92.6	Very high	91.9	Very high	60 Å²	60	69 Å²	69	36%	0.364	34%	0.337	S	S	.	.	H	α-helix	trans	-61.3	-50.5	176.9	167	0	0	0	0	110.6	I148 L149 L150 Y154 K155 Y156	I148-V152 HydrophobicContact CG2-CG2 4.12Å; I148-V152 WeakPolarHBondContact O-CB 3.29Å; I148-V152 VanDerWaalsContact O-CG2 3.23Å; I148-V152 WeakPolarHBondContact O-CG2 3.28Å; I148-V152 PolarHBondContact O-N 3.05Å; L149-V152 PolarHBondContact O-N 3.43Å; L150-V152 PolarHBondContact O-N 3.09Å; V152-Y154 VanDerWaalsContact C-N 3.29Å; V152-Y154 PolarHBondContact O-N 2.63Å; V152-K155 PolarHBondContact O-N 3.3Å; V152-Y156 HydrophobicContact CG1-CD2 3.62Å; V152-Y156 HydrophobicContact CG1-CE2 3.68Å; V152-Y156 WeakPolarHBondContact O-CD2 3.34Å; V152-Y156 PolarHBondContact O-N 2.93Å
153	L	93	Very high	91.6	Very high	31 Å²	31	71.9 Å²	71.9	16%	0.162	35%	0.348	C	S	.	.	H	α-helix	trans	-59.9	-38.7	177.4	-71.9	172.9	0	0	0	112.2	L149 L150 R157 C158 V161 I162	L149-L153 HydrophobicContact CD1-CD1 4.39Å; L149-L153 HydrophobicContact CD1-CG 4.39Å; L149-L153 HydrophobicContact CG-CD1 4.13Å; L149-L153 WeakPolarHBondContact O-CB 3.39Å; L149-L153 VanDerWaalsContact O-CG 3.27Å; L149-L153 WeakPolarHBondContact O-CG 3.49Å; L149-L153 PolarHBondContact O-N 2.84Å; L150-L153 PolarHBondContact O-N 2.96Å; L153-R157 PolarHBondContact O-N 3.47Å; L153-C158 HydrophobicContact CB-CB 4.35Å; L153-C158 HydrophobicContact CD2-CB 3.84Å; L153-C158 PolarHBondContact O-N 3.01Å; L153-V161 HydrophobicContact CD1-CG1 3.95Å; L153-V161 HydrophobicContact CD2-CG1 4.48Å; L153-I162 HydrophobicContact CB-CD1 4.13Å; L153-I162 HydrophobicContact CB-CG1 4.03Å
154	Y	89.6	Confident	91.7	Very high	7 Å²	7	72.4 Å²	72.4	3%	0.027	36%	0.358	C	S	.	.	H	α-helix	trans	-68.1	-41.1	177.7	-173.1	-112.2	0	0	0	111.9	L150 V151 V152 R157 Y159 I162 L271 T274 A275 R278 E280 F283	L150-Y154 WeakPolarHBondContact O-CB 3.27Å; L150-Y154 PolarHBondContact O-N 3.38Å; V151-Y154 PolarHBondContact O-N 2.94Å; V152-Y154 VanDerWaalsContact C-N 3.29Å; V152-Y154 PolarHBondContact O-N 2.63Å; Y154-R157 PolarHBondContact O-N 3.33Å; Y154-Y159 HydrophobicContact CD2-CE1 4.26Å; Y154-Y159 AromaticContact CE2-CE1 3.87Å; Y154-Y159 HydrophobicContact CE2-CE1 3.87Å; Y154-I162 HydrophobicContact CD2-CD1 4.12Å; Y154-L271 HydrophobicContact CD1-CG 4.31Å; Y154-T274 HydrophobicContact CD1-CG2 4.14Å; Y154-T274 HydrophobicContact CE1-CG2 3.72Å; Y154-A275 HydrophobicContact CE1-CB 4.44Å; Y154-R278 PolarHBondContact O-NH1 3.37Å; Y154-E280 PolarHBondContact OH-OE2 3.01Å; Y154-E280 VanDerWaalsContact OH-OE2 3.1Å; Y154-F283 HydrophobicContact CD2-CE2 4.24Å; Y154-F283 AromaticContact CD2-CZ 3.78Å; Y154-F283 HydrophobicContact CD2-CZ 3.78Å; Y154-F283 HydrophobicContact CE2-CZ 4.07Å
155	K	89.3	Confident	91.7	Very high	120 Å²	120	75.4 Å²	75.4	52%	0.522	37%	0.366	S	S	.	.	H	α-helix	trans	-62.6	-45.1	175.9	-170	169.8	-174.9	168.9	0	111.7	V151 V152 R157 M270	V151-K155 WeakPolarHBondContact O-CB 3.35Å; V151-K155 PolarHBondContact O-N 3.16Å; V152-K155 PolarHBondContact O-N 3.3Å; K155-R157 PolarHBondContact O-N 3.19Å; K155-M270 HydrophobicContact CD-SD 4.17Å
156	Y	91.4	Very high	91.5	Very high	173 Å²	173	71.9 Å²	71.9	68%	0.678	34%	0.344	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.7	8.1	177.6	-71.8	-66.9	0	0	0	114.7	V152 C158	V152-Y156 HydrophobicContact CG1-CD2 3.62Å; V152-Y156 HydrophobicContact CG1-CE2 3.68Å; V152-Y156 WeakPolarHBondContact O-CD2 3.34Å; V152-Y156 PolarHBondContact O-N 2.93Å; Y156-C158 PolarHBondContact O-N 3.4Å
157	R	88.3	Confident	91.5	Very high	169 Å²	169	70.8 Å²	70.8	64%	0.638	34%	0.339	S	S	*	.	T	Hydrogen-bonded Turn	trans	57.5	30.2	178.6	-61.5	-173.8	175.8	-172.8	-1.1	113.7	L153 Y154 K155 Y159	L153-R157 PolarHBondContact O-N 3.47Å; Y154-R157 PolarHBondContact O-N 3.33Å; K155-R157 PolarHBondContact O-N 3.19Å; R157-Y159 HydrophobicContact CB-CD2 4Å; R157-Y159 HydrophobicContact CB-CE2 3.64Å; R157-Y159 HydrophobicContact CG-CE2 3.87Å; R157-Y159 VanDerWaalsContact O-CD2 3.24Å; R157-Y159 WeakPolarHBondContact O-CD2 3.24Å; R157-Y159 PolarHBondContact O-N 3.26Å
158	C	90.9	Very high	91.7	Very high	49 Å²	49	74.4 Å²	74.4	33%	0.331	36%	0.356	S	S	.	.			trans	-77.9	53	174.8	-63.4	0	0	0	0	111.8	L153 Y156 K160 V161 I162	L153-C158 HydrophobicContact CB-CB 4.35Å; L153-C158 HydrophobicContact CD2-CB 3.84Å; L153-C158 PolarHBondContact O-N 3.01Å; Y156-C158 PolarHBondContact O-N 3.4Å; C158-K160 VanDerWaalsContact C-N 3.27Å; C158-K160 PolarHBondContact O-N 2.93Å; C158-V161 HydrophobicContact CB-CG2 4.4Å; C158-V161 PolarHBondContact O-N 3.49Å; C158-V161 VanDerWaalsContact O-N 3.1Å; C158-I162 PolarHBondContact O-N 3.09Å
159	Y	88.2	Confident	91.7	Very high	59 Å²	59	73 Å²	73	23%	0.231	35%	0.353	C	S	.	.	H	α-helix	trans	-58.5	-35.2	-173.2	-67	-78.6	0	0	0	113.3	Y154 R157 V161 I162 H163 R278 E280	Y154-Y159 HydrophobicContact CD2-CE1 4.26Å; Y154-Y159 AromaticContact CE2-CE1 3.87Å; Y154-Y159 HydrophobicContact CE2-CE1 3.87Å; R157-Y159 HydrophobicContact CB-CD2 4Å; R157-Y159 HydrophobicContact CB-CE2 3.64Å; R157-Y159 HydrophobicContact CG-CE2 3.87Å; R157-Y159 VanDerWaalsContact O-CD2 3.24Å; R157-Y159 WeakPolarHBondContact O-CD2 3.24Å; R157-Y159 PolarHBondContact O-N 3.26Å; Y159-V161 VanDerWaalsContact C-N 3.31Å; Y159-V161 PolarHBondContact O-N 2.92Å; Y159-I162 PolarHBondContact O-N 3.11Å; Y159-H163 WeakPolarHBondContact O-CB 3.47Å; Y159-H163 PolarHBondContact O-CD2 3.32Å; Y159-H163 PolarHBondContact O-N 3.22Å; Y159-R278 PolarHBondContact OH-NH1 2.96Å; Y159-E280 PolarHBondContact OH-OE1 3.48Å; Y159-E280 VanDerWaalsContact OH-OE1 3.06Å; Y159-E280 PolarHBondContact OH-OE2 3.23Å
160	K	92.7	Very high	91.6	Very high	189 Å²	189	69.5 Å²	69.5	82%	0.822	34%	0.336	S	S	*	.	H	α-helix	trans	-58.4	-42.1	177.3	-68.6	-174.4	178.6	178.6	0	112.3	C158 A164	C158-K160 VanDerWaalsContact C-N 3.27Å; C158-K160 PolarHBondContact O-N 2.93Å; K160-A164 VanDerWaalsContact O-CB 3.25Å; K160-A164 WeakPolarHBondContact O-CB 3.04Å; K160-A164 PolarHBondContact O-N 2.91Å
161	V	94.3	Very high	91.8	Very high	77 Å²	77	71.5 Å²	71.5	47%	0.467	35%	0.346	S	S	.	.	H	α-helix	trans	-68.9	-43.1	-179.7	-179.4	0	0	0	0	110.2	L153 C158 Y159 A164 W165	L153-V161 HydrophobicContact CD1-CG1 3.95Å; L153-V161 HydrophobicContact CD2-CG1 4.48Å; C158-V161 HydrophobicContact CB-CG2 4.4Å; C158-V161 PolarHBondContact O-N 3.49Å; C158-V161 VanDerWaalsContact O-N 3.1Å; Y159-V161 VanDerWaalsContact C-N 3.31Å; Y159-V161 PolarHBondContact O-N 2.92Å; V161-A164 PolarHBondContact O-N 3.43Å; V161-W165 WeakPolarHBondContact O-CB 3.47Å; V161-W165 PolarHBondContact O-N 2.94Å
162	I	90.9	Very high	92	Very high	1 Å²	1	75.2 Å²	75.2	1%	0.005	37%	0.365	C	S	.	.	H	α-helix	trans	-66.1	-46.2	-179.7	-54.9	169.6	0	0	0	110.8	L153 Y154 C158 Y159 A164 W165 L166 F283	L153-I162 HydrophobicContact CB-CD1 4.13Å; L153-I162 HydrophobicContact CB-CG1 4.03Å; Y154-I162 HydrophobicContact CD2-CD1 4.12Å; C158-I162 PolarHBondContact O-N 3.09Å; Y159-I162 PolarHBondContact O-N 3.11Å; I162-A164 PolarHBondContact O-N 3.34Å; I162-W165 PolarHBondContact O-N 3.42Å; I162-L166 HydrophobicContact CG2-CD1 4.14Å; I162-L166 HydrophobicContact CG2-CG 4.38Å; I162-L166 WeakPolarHBondContact O-CG 3.44Å; I162-L166 PolarHBondContact O-N 3.22Å; I162-F283 HydrophobicContact CB-CE1 4.29Å; I162-F283 HydrophobicContact CB-CZ 4.26Å; I162-F283 HydrophobicContact CD1-CZ 3.98Å; I162-F283 HydrophobicContact CG2-CD1 4.15Å; I162-F283 HydrophobicContact CG2-CE1 3.45Å; I162-F283 VanDerWaalsContact CG2-CE1 3.45Å; I162-F283 HydrophobicContact CG2-CE2 3.97Å; I162-F283 HydrophobicContact CG2-CZ 3.37Å
163	H	88.9	Confident	92.1	Very high	98 Å²	98	72.9 Å²	72.9	45%	0.454	35%	0.351	S	S	.	.	H	α-helix	trans	-61.3	-44.7	175.6	-81	-68.7	0	0	0	112	Y159 W165 L166 I167	Y159-H163 WeakPolarHBondContact O-CB 3.47Å; Y159-H163 PolarHBondContact O-CD2 3.32Å; Y159-H163 PolarHBondContact O-N 3.22Å; H163-W165 PolarHBondContact O-N 2.85Å; H163-L166 PolarHBondContact O-N 3.5Å; H163-I167 WeakPolarHBondContact O-CB 3.33Å; H163-I167 WeakPolarHBondContact O-CG1 2.81Å; H163-I167 PolarHBondContact O-N 3.04Å
164	A	93.6	Very high	92.2	Very high	54 Å²	54	71.4 Å²	71.4	45%	0.446	34%	0.343	S	S	.	.	H	α-helix	trans	-60.5	-45.5	176.3	0	0	0	0	0	111.4	K160 V161 I162 I167 I168	K160-A164 VanDerWaalsContact O-CB 3.25Å; K160-A164 WeakPolarHBondContact O-CB 3.04Å; K160-A164 PolarHBondContact O-N 2.91Å; V161-A164 PolarHBondContact O-N 3.43Å; I162-A164 PolarHBondContact O-N 3.34Å; A164-I167 PolarHBondContact O-N 3.38Å; A164-I168 WeakPolarHBondContact O-CB 3.25Å; A164-I168 VanDerWaalsContact O-CG1 3.23Å; A164-I168 WeakPolarHBondContact O-CG1 3.24Å; A164-I168 PolarHBondContact O-N 3.46Å
165	W	93.6	Very high	92.5	Very high	99 Å²	99	73.5 Å²	73.5	38%	0.375	35%	0.353	S	S	.	.	H	α-helix	trans	-62.5	-44.5	178.8	179	29.8	0	0	0	112.4	L150 V161 I162 H163 I168 S169	L150-W165 HydrophobicContact CB-CH2 4.42Å; L150-W165 HydrophobicContact CB-CZ3 3.89Å; L150-W165 HydrophobicContact CD1-CH2 4.09Å; L150-W165 HydrophobicContact CD1-CZ3 3.67Å; L150-W165 HydrophobicContact CG-CZ3 3.85Å; V161-W165 WeakPolarHBondContact O-CB 3.47Å; V161-W165 PolarHBondContact O-N 2.94Å; I162-W165 PolarHBondContact O-N 3.42Å; H163-W165 PolarHBondContact O-N 2.85Å; W165-I168 PolarHBondContact O-N 3.35Å; W165-S169 WeakPolarHBondContact O-CB 3.35Å; W165-S169 PolarHBondContact O-N 3.22Å
166	L	91.1	Very high	92.9	Very high	17 Å²	17	73.4 Å²	73.4	9%	0.089	35%	0.352	C	S	.	.	H	α-helix	trans	-63	-43	176.6	-69.6	178.2	0	0	0	112.2	I162 H163 S169 S170 F283 L286	I162-L166 HydrophobicContact CG2-CD1 4.14Å; I162-L166 HydrophobicContact CG2-CG 4.38Å; I162-L166 WeakPolarHBondContact O-CG 3.44Å; I162-L166 PolarHBondContact O-N 3.22Å; H163-L166 PolarHBondContact O-N 3.5Å; L166-S169 PolarHBondContact O-N 3.36Å; L166-S170 WeakPolarHBondContact O-CB 3.39Å; L166-S170 PolarHBondContact O-N 3.32Å; L166-S170 PolarHBondContact O-OG 3.34Å; L166-F283 HydrophobicContact CD1-CB 3.69Å; L166-F283 HydrophobicContact CD1-CD1 3.55Å; L166-F283 HydrophobicContact CD1-CD2 4.42Å; L166-F283 HydrophobicContact CD1-CE1 4.34Å; L166-F283 HydrophobicContact CD1-CG 3.62Å; L166-L286 HydrophobicContact CD1-CD1 4.27Å; L166-L286 HydrophobicContact CD2-CD1 3.49Å; L166-L286 VanDerWaalsContact CD2-CD1 3.49Å; L166-L286 HydrophobicContact CD2-CG 4.19Å
167	I	93.5	Very high	93.1	Very high	56 Å²	56	67 Å²	67	29%	0.287	33%	0.328	S	S	.	.	H	α-helix	trans	-60.7	-47.9	176.1	-69.1	-76.3	0	0	0	110.6	H163 A164 S169 S170 L171 M210 H214	H163-I167 WeakPolarHBondContact O-CB 3.33Å; H163-I167 WeakPolarHBondContact O-CG1 2.81Å; H163-I167 PolarHBondContact O-N 3.04Å; A164-I167 PolarHBondContact O-N 3.38Å; I167-S169 PolarHBondContact O-N 3.23Å; I167-S170 PolarHBondContact O-N 3.35Å; I167-L171 HydrophobicContact CG2-CD1 3.82Å; I167-L171 HydrophobicContact CG2-CG 4.27Å; I167-L171 WeakPolarHBondContact O-CB 3.23Å; I167-L171 VanDerWaalsContact O-CG 3.23Å; I167-L171 WeakPolarHBondContact O-CG 3.17Å; I167-L171 PolarHBondContact O-N 2.84Å; I167-M210 HydrophobicContact CB-CE 4.46Å; I167-M210 HydrophobicContact CD1-CE 3.64Å; I167-M210 HydrophobicContact CG2-CE 3.93Å; I167-H214 HydrophobicContact CD1-CB 3.91Å; I167-H214 WeakPolarHBondContact CD1-CD2 3.49Å
168	I	95.1	Very high	93.4	Very high	106 Å²	106	59.2 Å²	59.2	54%	0.544	30%	0.3	S	S	.	.	H	α-helix	trans	-63	-43.1	178.9	-66.1	-65.2	0	0	0	111.1	A164 W165 S170 L171 L172	A164-I168 WeakPolarHBondContact O-CB 3.25Å; A164-I168 VanDerWaalsContact O-CG1 3.23Å; A164-I168 WeakPolarHBondContact O-CG1 3.24Å; A164-I168 PolarHBondContact O-N 3.46Å; W165-I168 PolarHBondContact O-N 3.35Å; I168-S170 PolarHBondContact O-N 2.89Å; I168-L171 PolarHBondContact O-N 2.96Å; I168-L172 WeakPolarHBondContact O-CB 3.3Å; I168-L172 PolarHBondContact O-N 3.24Å
169	S	92.4	Very high	93.7	Very high	52 Å²	52	61.9 Å²	61.9	36%	0.364	31%	0.306	S	S	.	.	H	α-helix	trans	-61.5	-44.5	177.1	-170.5	0	0	0	0	111.7	W165 L166 I167 L173	W165-S169 WeakPolarHBondContact O-CB 3.35Å; W165-S169 PolarHBondContact O-N 3.22Å; L166-S169 PolarHBondContact O-N 3.36Å; I167-S169 PolarHBondContact O-N 3.23Å; S169-L173 PolarHBondContact O-N 3.46Å; S169-L173 VanDerWaalsContact O-N 3.1Å
170	S	92.4	Very high	94	Very high	10 Å²	10	60.9 Å²	60.9	7%	0.07	30%	0.304	C	S	.	.	H	α-helix	trans	-70.8	-37.2	178.3	-64.2	0	0	0	0	112.9	L166 I167 I168 L173 L174 H214	L166-S170 WeakPolarHBondContact O-CB 3.39Å; L166-S170 PolarHBondContact O-N 3.32Å; L166-S170 PolarHBondContact O-OG 3.34Å; I167-S170 PolarHBondContact O-N 3.35Å; I168-S170 PolarHBondContact O-N 2.89Å; S170-L173 PolarHBondContact O-N 2.92Å; S170-L174 VanDerWaalsContact O-CB 3.32Å; S170-L174 WeakPolarHBondContact O-CB 3.35Å; S170-L174 WeakPolarHBondContact O-CG 3.25Å; S170-L174 PolarHBondContact O-N 3.28Å; S170-H214 PolarHBondContact OG-CE1 3.36Å
171	L	95	Very high	94.2	Very high	63 Å²	63	54.4 Å²	54.4	33%	0.33	28%	0.275	S	S	.	.	H	α-helix	trans	-61.3	-46.9	174	-76.6	174.3	0	0	0	111.1	I167 I168 L173 L174 F175 M210	I167-L171 HydrophobicContact CG2-CD1 3.82Å; I167-L171 HydrophobicContact CG2-CG 4.27Å; I167-L171 WeakPolarHBondContact O-CB 3.23Å; I167-L171 VanDerWaalsContact O-CG 3.23Å; I167-L171 WeakPolarHBondContact O-CG 3.17Å; I167-L171 PolarHBondContact O-N 2.84Å; I168-L171 PolarHBondContact O-N 2.96Å; L171-L173 VanDerWaalsContact C-N 3.31Å; L171-L173 PolarHBondContact O-N 2.94Å; L171-L174 PolarHBondContact O-N 2.83Å; L171-F175 HydrophobicContact CD2-CD2 3.83Å; L171-F175 HydrophobicContact CD2-CE2 3.48Å; L171-F175 VanDerWaalsContact CD2-CE2 3.48Å; L171-F175 HydrophobicContact CD2-CZ 4.48Å; L171-F175 WeakPolarHBondContact O-CB 3.41Å; L171-F175 WeakPolarHBondContact O-CD2 3.48Å; L171-F175 PolarHBondContact O-N 3.46Å; L171-M210 HydrophobicContact CD2-CE 3.85Å; L171-M210 HydrophobicContact CD2-CG 3.71Å; L171-M210 HydrophobicContact CD2-SD 3.79Å; L171-M210 HydrophobicContact CG-CE 3.79Å; L171-M210 HydrophobicContact CG-SD 4.04Å
172	L	95	Very high	94.3	Very high	89 Å²	89	52.3 Å²	52.3	47%	0.466	26%	0.261	S	S	.	.	I	π-helix	trans	-59.8	-44.1	177.7	-172	151.5	0	0	0	110.7	I168 F176 F177	I168-L172 WeakPolarHBondContact O-CB 3.3Å; I168-L172 PolarHBondContact O-N 3.24Å; L172-F176 VanDerWaalsContact O-CB 3.26Å; L172-F176 WeakPolarHBondContact O-CB 3.26Å; L172-F176 PolarHBondContact O-N 3.4Å; L172-F177 HydrophobicContact CD2-CD2 3.6Å; L172-F177 HydrophobicContact CD2-CE2 3.27Å; L172-F177 HydrophobicContact CD2-CZ 4.3Å; L172-F177 PolarHBondContact O-N 3.19Å
173	L	94	Very high	94.5	Very high	12 Å²	12	53.4 Å²	53.4	6%	0.063	27%	0.272	C	S	.	.	I	π-helix	trans	-67	-49.6	178.4	-81.2	161.6	0	0	0	113.8	S169 S170 L171 F177 S178 I229 M233	S169-L173 PolarHBondContact O-N 3.46Å; S169-L173 VanDerWaalsContact O-N 3.1Å; S170-L173 PolarHBondContact O-N 2.92Å; L171-L173 VanDerWaalsContact C-N 3.31Å; L171-L173 PolarHBondContact O-N 2.94Å; L173-F177 HydrophobicContact CD2-CB 4.39Å; L173-F177 HydrophobicContact CD2-CD2 3.48Å; L173-F177 VanDerWaalsContact CD2-CD2 3.48Å; L173-F177 HydrophobicContact CD2-CE2 4.07Å; L173-F177 HydrophobicContact CD2-CG 4.24Å; L173-F177 HydrophobicContact CG-CD2 4.21Å; L173-S178 PolarHBondContact O-N 3.06Å; L173-S178 PolarHBondContact O-OG 3.01Å; L173-I229 HydrophobicContact CD1-CG2 4.02Å; L173-M233 HydrophobicContact CD1-CG 3.8Å; L173-M233 HydrophobicContact CD1-SD 3.62Å; L173-M233 HydrophobicContact CD2-CG 3.72Å; L173-M233 HydrophobicContact CD2-SD 3.34Å; L173-M233 WeakPolarHBondContact CD2-SD 3.37Å; L173-M233 HydrophobicContact CG-CG 4.42Å; L173-M233 HydrophobicContact CG-SD 4.01Å
174	L	95.9	Very high	94.8	Very high	0 Å²	0	50 Å²	50	0%	0	26%	0.257	C	S	.	.	I	π-helix	trans	-73.6	-33.1	-174.2	-73.9	176.2	0	0	0	113.4	S170 L171 S178 F205 M210 I213 Y225 I229	S170-L174 VanDerWaalsContact O-CB 3.32Å; S170-L174 WeakPolarHBondContact O-CB 3.35Å; S170-L174 WeakPolarHBondContact O-CG 3.25Å; S170-L174 PolarHBondContact O-N 3.28Å; L171-L174 PolarHBondContact O-N 2.83Å; L174-S178 WeakPolarHBondContact O-CB 3.15Å; L174-S178 PolarHBondContact O-OG 3.24Å; L174-F205 HydrophobicContact CD2-CD1 4.46Å; L174-F205 HydrophobicContact CD2-CE1 3.68Å; L174-F205 HydrophobicContact CD2-CZ 4.18Å; L174-M210 HydrophobicContact CD1-CG 4.19Å; L174-M210 HydrophobicContact CD1-SD 3.95Å; L174-I213 HydrophobicContact CD1-CD1 4.18Å; L174-Y225 HydrophobicContact CD2-CD1 3.92Å; L174-Y225 HydrophobicContact CD2-CE1 4.35Å; L174-I229 HydrophobicContact CD1-CD1 4.4Å; L174-I229 HydrophobicContact CD2-CD1 3.87Å; L174-I229 HydrophobicContact CD2-CG1 3.77Å; L174-I229 HydrophobicContact CG-CD1 4.04Å; L174-I229 HydrophobicContact CG-CG1 4.3Å
175	F	96.9	Very high	94.9	Very high	51 Å²	51	48.7 Å²	48.7	22%	0.224	24%	0.243	C	C	.	.	I	π-helix	trans	-93.8	-57.4	-179.6	-71.5	-94.8	0	0	0	111.7	L171 F179 I202 W203 G206 V207 M210	L171-F175 HydrophobicContact CD2-CD2 3.83Å; L171-F175 HydrophobicContact CD2-CE2 3.48Å; L171-F175 VanDerWaalsContact CD2-CE2 3.48Å; L171-F175 HydrophobicContact CD2-CZ 4.48Å; L171-F175 WeakPolarHBondContact O-CB 3.41Å; L171-F175 WeakPolarHBondContact O-CD2 3.48Å; L171-F175 PolarHBondContact O-N 3.46Å; F175-F179 WeakPolarHBondContact O-CB 3.31Å; F175-F179 PolarHBondContact O-N 2.96Å; F175-I202 HydrophobicContact CD1-CG2 4.15Å; F175-W203 HydrophobicContact CE1-CE3 4.16Å; F175-G206 VanDerWaalsContact CZ-C 3.48Å; F175-V207 HydrophobicContact CZ-CG2 4.12Å; F175-M210 HydrophobicContact CE2-CG 4.21Å
176	F	96.1	Very high	95.1	Very high	118 Å²	118	46.3 Å²	46.3	52%	0.518	24%	0.235	S	C	.	.	I	π-helix	trans	-74.8	-51.3	-170.6	-179.3	-103.3	0	0	0	112.6	L172 F179 I180	L172-F176 VanDerWaalsContact O-CB 3.26Å; L172-F176 WeakPolarHBondContact O-CB 3.26Å; L172-F176 PolarHBondContact O-N 3.4Å; F176-F179 WeakPolarHBondContact O-CB 3.38Å; F176-F179 PolarHBondContact O-N 3.34Å; F176-I180 HydrophobicContact CD1-CD1 4.04Å; F176-I180 HydrophobicContact CE1-CD1 3.5Å; F176-I180 HydrophobicContact CE2-CD1 4.32Å; F176-I180 HydrophobicContact CZ-CD1 3.67Å; F176-I180 PolarHBondContact O-N 3.39Å; F176-I180 VanDerWaalsContact O-N 3.11Å
177	F	95.3	Very high	95.3	Very high	37 Å²	37	51.8 Å²	51.8	16%	0.162	26%	0.258	C	S	.	.	I	π-helix	trans	-70.1	-35.1	-179.4	-76.7	-64.3	0	0	0	112.7	L172 L173 F179 I180 Y181 V236	L172-F177 HydrophobicContact CD2-CD2 3.6Å; L172-F177 HydrophobicContact CD2-CE2 3.27Å; L172-F177 HydrophobicContact CD2-CZ 4.3Å; L172-F177 PolarHBondContact O-N 3.19Å; L173-F177 HydrophobicContact CD2-CB 4.39Å; L173-F177 HydrophobicContact CD2-CD2 3.48Å; L173-F177 VanDerWaalsContact CD2-CD2 3.48Å; L173-F177 HydrophobicContact CD2-CE2 4.07Å; L173-F177 HydrophobicContact CD2-CG 4.24Å; L173-F177 HydrophobicContact CG-CD2 4.21Å; F177-F179 VanDerWaalsContact C-N 3.32Å; F177-F179 PolarHBondContact O-N 2.87Å; F177-I180 HydrophobicContact CD1-CD1 4.45Å; F177-I180 PolarHBondContact O-N 3.1Å; F177-Y181 WeakPolarHBondContact O-CB 3.38Å; F177-Y181 PolarHBondContact O-N 3.41Å; F177-V236 HydrophobicContact CD1-CG2 3.42Å; F177-V236 VanDerWaalsContact CD1-CG2 3.42Å; F177-V236 HydrophobicContact CD2-CG2 4.39Å; F177-V236 HydrophobicContact CE1-CB 4.4Å; F177-V236 HydrophobicContact CE1-CG1 4.15Å; F177-V236 HydrophobicContact CE1-CG2 3.29Å; F177-V236 HydrophobicContact CE2-CG2 4.24Å; F177-V236 HydrophobicContact CG-CG2 4Å; F177-V236 HydrophobicContact CZ-CG1 4.04Å; F177-V236 HydrophobicContact CZ-CG2 3.72Å
178	S	95.9	Very high	95.4	Very high	7 Å²	7	51.8 Å²	51.8	5%	0.049	26%	0.261	C	S	.	.	H	α-helix	trans	-65.6	-35.2	172.3	-47.1	0	0	0	0	112.7	L173 L174 Y181 L182 F205 L232	L173-S178 PolarHBondContact O-N 3.06Å; L173-S178 PolarHBondContact O-OG 3.01Å; L174-S178 WeakPolarHBondContact O-CB 3.15Å; L174-S178 PolarHBondContact O-OG 3.24Å; S178-Y181 PolarHBondContact O-N 3.36Å; S178-L182 VanDerWaalsContact O-CB 3.27Å; S178-L182 WeakPolarHBondContact O-CB 3.03Å; S178-L182 PolarHBondContact O-N 3.48Å; S178-F205 WeakPolarHBondContact OG-CE1 3.28Å; S178-L232 WeakPolarHBondContact OG-CD1 3.27Å
179	F	96.6	Very high	95.4	Very high	104 Å²	104	54.2 Å²	54.2	46%	0.456	27%	0.265	S	S	.	.	H	α-helix	trans	-62.2	-46	173.9	172.2	-97.9	0	0	0	111.3	F175 F176 F177 G183 V198 I202	F175-F179 WeakPolarHBondContact O-CB 3.31Å; F175-F179 PolarHBondContact O-N 2.96Å; F176-F179 WeakPolarHBondContact O-CB 3.38Å; F176-F179 PolarHBondContact O-N 3.34Å; F177-F179 VanDerWaalsContact C-N 3.32Å; F177-F179 PolarHBondContact O-N 2.87Å; F179-G183 PolarHBondContact O-N 3.48Å; F179-V198 HydrophobicContact CD2-CG1 3.91Å; F179-V198 HydrophobicContact CE2-CG1 3.82Å; F179-I202 HydrophobicContact CB-CD1 4.36Å; F179-I202 HydrophobicContact CB-CG1 4.38Å; F179-I202 HydrophobicContact CD2-CG1 4.35Å
180	I	95.2	Very high	95.6	Very high	39 Å²	39	59 Å²	59	20%	0.2	29%	0.286	C	S	.	.	H	α-helix	trans	-61.6	-49.8	174.6	-64.7	171.3	0	0	0	110.3	F105 F176 F177 L182 G183 E184	F105-I180 HydrophobicContact CE1-CG2 4.48Å; F176-I180 HydrophobicContact CD1-CD1 4.04Å; F176-I180 HydrophobicContact CE1-CD1 3.5Å; F176-I180 HydrophobicContact CE2-CD1 4.32Å; F176-I180 HydrophobicContact CZ-CD1 3.67Å; F176-I180 PolarHBondContact O-N 3.39Å; F176-I180 VanDerWaalsContact O-N 3.11Å; F177-I180 HydrophobicContact CD1-CD1 4.45Å; F177-I180 PolarHBondContact O-N 3.1Å; I180-L182 PolarHBondContact O-N 2.95Å; I180-G183 PolarHBondContact O-N 2.96Å; I180-G183 VanDerWaalsContact O-N 3.16Å; I180-E184 HydrophobicContact CG2-CG 4.37Å; I180-E184 WeakPolarHBondContact O-CG 3.11Å; I180-E184 PolarHBondContact O-N 3.39Å
181	Y	96.4	Very high	95.8	Very high	53 Å²	53	62.3 Å²	62.3	21%	0.208	31%	0.305	C	S	.	.	H	α-helix	trans	-54.9	-52	179.9	176.3	-95.5	0	0	0	111.8	T99 Y106 F177 S178 G183 E184 V185 L232 L235	T99-Y181 HydrophobicContact CG2-CD2 4.4Å; T99-Y181 HydrophobicContact CG2-CE2 3.64Å; T99-Y181 PolarHBondContact OG1-OH 3.43Å; Y106-Y181 HydrophobicContact CE2-CD2 4.17Å; Y106-Y181 WeakPolarHBondContact OH-CD2 3.47Å; F177-Y181 WeakPolarHBondContact O-CB 3.38Å; F177-Y181 PolarHBondContact O-N 3.41Å; S178-Y181 PolarHBondContact O-N 3.36Å; Y181-G183 VanDerWaalsContact C-N 3.3Å; Y181-G183 PolarHBondContact O-N 2.93Å; Y181-E184 PolarHBondContact O-N 3.22Å; Y181-V185 HydrophobicContact CD1-CG2 4.25Å; Y181-V185 HydrophobicContact CE1-CG2 3.86Å; Y181-V185 HydrophobicContact CE2-CG2 4.39Å; Y181-V185 VanDerWaalsContact O-CG2 3.31Å; Y181-V185 WeakPolarHBondContact O-CG2 3.4Å; Y181-V185 PolarHBondContact O-N 3.01Å; Y181-L232 HydrophobicContact CD2-CD2 3.99Å; Y181-L232 HydrophobicContact CG-CD2 3.87Å; Y181-L235 HydrophobicContact CD2-CD1 4.03Å; Y181-L235 HydrophobicContact CE2-CD1 3.98Å
182	L	96.2	Very high	95.8	Very high	33 Å²	33	64.4 Å²	64.4	17%	0.173	33%	0.332	C	S	.	.	H	α-helix	trans	-62.8	-39.3	179.2	-173.5	63.4	0	0	0	111.5	S178 I180 E184 V185 F186 V198 L201 I202	S178-L182 VanDerWaalsContact O-CB 3.27Å; S178-L182 WeakPolarHBondContact O-CB 3.03Å; S178-L182 PolarHBondContact O-N 3.48Å; I180-L182 PolarHBondContact O-N 2.95Å; L182-E184 PolarHBondContact O-N 3.31Å; L182-V185 PolarHBondContact O-N 3.14Å; L182-F186 HydrophobicContact CD1-CD2 4.34Å; L182-F186 HydrophobicContact CD1-CE1 4.26Å; L182-F186 HydrophobicContact CD1-CE2 3.68Å; L182-F186 HydrophobicContact CD1-CZ 3.62Å; L182-F186 HydrophobicContact CD2-CE2 3.84Å; L182-F186 HydrophobicContact CD2-CZ 4.3Å; L182-F186 HydrophobicContact CG-CD2 3.99Å; L182-F186 HydrophobicContact CG-CE2 3.43Å; L182-F186 VanDerWaalsContact CG-CE2 3.43Å; L182-F186 HydrophobicContact CG-CZ 3.93Å; L182-F186 VanDerWaalsContact O-CD2 3.32Å; L182-F186 WeakPolarHBondContact O-CD2 3.33Å; L182-F186 WeakPolarHBondContact O-CG 3.41Å; L182-F186 PolarHBondContact O-N 3.15Å; L182-V198 HydrophobicContact CD2-CG1 4.48Å; L182-L201 HydrophobicContact CD2-CB 4.41Å; L182-L201 HydrophobicContact CD2-CD2 4.38Å; L182-I202 HydrophobicContact CB-CD1 4.31Å; L182-I202 HydrophobicContact CD2-CD1 3.85Å; L182-I202 HydrophobicContact CD2-CG1 4.16Å
183	G	95.5	Very high	95.8	Very high	23 Å²	23	62.5 Å²	62.5	24%	0.237	32%	0.324	C	S	.	.	H	α-helix	trans	-62.9	-37.4	175.5	0	0	0	0	0	113.5	F179 I180 Y181 K187	F179-G183 PolarHBondContact O-N 3.48Å; I180-G183 PolarHBondContact O-N 2.96Å; I180-G183 VanDerWaalsContact O-N 3.16Å; Y181-G183 VanDerWaalsContact C-N 3.3Å; Y181-G183 PolarHBondContact O-N 2.93Å; G183-K187 WeakPolarHBondContact O-CG 3.27Å; G183-K187 PolarHBondContact O-N 2.83Å; G183-K187 PolarHBondContact O-NZ 3.48Å
184	E	95.5	Very high	96	Very high	28 Å²	28	65.8 Å²	65.8	13%	0.131	34%	0.341	C	S	.	.	H	α-helix	trans	-76.2	-33.9	175.9	-66.4	-52.6	128.7	0	0	112.4	V103 F105 I180 Y181 L182 K187 T188	V103-E184 HydrophobicContact CG1-CB 3.89Å; F105-E184 HydrophobicContact CB-CB 4.29Å; F105-E184 HydrophobicContact CB-CG 4.03Å; F105-E184 WeakPolarHBondContact CB-OE2 3.37Å; F105-E184 HydrophobicContact CD1-CB 4.49Å; F105-E184 HydrophobicContact CD1-CG 3.65Å; F105-E184 VanDerWaalsContact CD2-CD 3.49Å; F105-E184 HydrophobicContact CD2-CG 4.04Å; F105-E184 WeakPolarHBondContact CD2-OE2 3.28Å; F105-E184 HydrophobicContact CE1-CG 4.06Å; F105-E184 HydrophobicContact CE2-CG 4.42Å; F105-E184 HydrophobicContact CG-CB 4.4Å; F105-E184 HydrophobicContact CG-CG 3.63Å; F105-E184 WeakPolarHBondContact CG-OE2 3.28Å; F105-E184 HydrophobicContact CZ-CG 4.42Å; I180-E184 HydrophobicContact CG2-CG 4.37Å; I180-E184 WeakPolarHBondContact O-CG 3.11Å; I180-E184 PolarHBondContact O-N 3.39Å; Y181-E184 PolarHBondContact O-N 3.22Å; L182-E184 PolarHBondContact O-N 3.31Å; E184-K187 PolarHBondContact O-N 3.44Å; E184-K187 IonicContact OE1-NZ 2.87Å; E184-K187 PolarHBondContact OE1-NZ 3.47Å; E184-T188 WeakPolarHBondContact O-CB 3.23Å; E184-T188 PolarHBondContact O-N 3.25Å; E184-T188 PolarHBondContact O-OG1 3.37Å
185	V	96.3	Very high	96	Very high	26 Å²	26	75.6 Å²	75.6	16%	0.158	38%	0.38	C	S	.	.	H	α-helix	trans	-60.4	-49.4	171.4	170.3	0	0	0	0	110.4	V103 Y181 L182 K187 T188 Y189	V103-V185 HydrophobicContact CG2-CG2 4.14Å; Y181-V185 HydrophobicContact CD1-CG2 4.25Å; Y181-V185 HydrophobicContact CE1-CG2 3.86Å; Y181-V185 HydrophobicContact CE2-CG2 4.39Å; Y181-V185 VanDerWaalsContact O-CG2 3.31Å; Y181-V185 WeakPolarHBondContact O-CG2 3.4Å; Y181-V185 PolarHBondContact O-N 3.01Å; L182-V185 PolarHBondContact O-N 3.14Å; V185-K187 PolarHBondContact O-N 3.24Å; V185-T188 WeakPolarHBondContact O-CB 3.39Å; V185-T188 PolarHBondContact O-N 3.07Å; V185-T188 VanDerWaalsContact O-N 3.17Å; V185-Y189 HydrophobicContact CG1-CD2 3.86Å; V185-Y189 HydrophobicContact CG1-CE2 3.94Å; V185-Y189 VanDerWaalsContact O-CD2 3.27Å; V185-Y189 WeakPolarHBondContact O-CD2 3.29Å; V185-Y189 PolarHBondContact O-N 3.17Å
186	F	96.3	Very high	96	Very high	49 Å²	49	79.5 Å²	79.5	22%	0.215	40%	0.402	C	S	.	.	H	α-helix	trans	-63.9	-37.6	178.4	-68.3	-40.8	0	0	0	113.3	L182 T188 Y189 N190 V191 V193 V198	L182-F186 HydrophobicContact CD1-CD2 4.34Å; L182-F186 HydrophobicContact CD1-CE1 4.26Å; L182-F186 HydrophobicContact CD1-CE2 3.68Å; L182-F186 HydrophobicContact CD1-CZ 3.62Å; L182-F186 HydrophobicContact CD2-CE2 3.84Å; L182-F186 HydrophobicContact CD2-CZ 4.3Å; L182-F186 HydrophobicContact CG-CD2 3.99Å; L182-F186 HydrophobicContact CG-CE2 3.43Å; L182-F186 VanDerWaalsContact CG-CE2 3.43Å; L182-F186 HydrophobicContact CG-CZ 3.93Å; L182-F186 VanDerWaalsContact O-CD2 3.32Å; L182-F186 WeakPolarHBondContact O-CD2 3.33Å; L182-F186 WeakPolarHBondContact O-CG 3.41Å; L182-F186 PolarHBondContact O-N 3.15Å; F186-T188 VanDerWaalsContact C-N 3.34Å; F186-Y189 PolarHBondContact O-N 2.81Å; F186-N190 PolarHBondContact O-N 3.07Å; F186-V191 PolarHBondContact O-N 3.1Å; F186-V191 VanDerWaalsContact O-N 3.08Å; F186-V193 HydrophobicContact CD1-CG2 3.8Å; F186-V193 HydrophobicContact CD2-CB 4.21Å; F186-V193 HydrophobicContact CD2-CG2 3.98Å; F186-V193 HydrophobicContact CE1-CG2 3.85Å; F186-V193 HydrophobicContact CE2-CB 4.19Å; F186-V193 HydrophobicContact CE2-CG1 4.13Å; F186-V193 HydrophobicContact CE2-CG2 3.99Å; F186-V193 HydrophobicContact CG-CG2 3.89Å; F186-V193 HydrophobicContact CZ-CG1 4.36Å; F186-V193 HydrophobicContact CZ-CG2 3.94Å; F186-V198 HydrophobicContact CD2-CG2 4.5Å; F186-V198 HydrophobicContact CE2-CG2 4.1Å
187	K	95.3	Very high	96	Very high	131 Å²	131	76.4 Å²	76.4	57%	0.57	39%	0.393	S	S	*	.	H	α-helix	trans	-62.1	-42	172.5	-73.9	-174.1	-156.7	84.1	0	111.9	G183 E184 V185 Y189 N190	G183-K187 WeakPolarHBondContact O-CG 3.27Å; G183-K187 PolarHBondContact O-N 2.83Å; G183-K187 PolarHBondContact O-NZ 3.48Å; E184-K187 PolarHBondContact O-N 3.44Å; E184-K187 IonicContact OE1-NZ 2.87Å; E184-K187 PolarHBondContact OE1-NZ 3.47Å; V185-K187 PolarHBondContact O-N 3.24Å; K187-Y189 PolarHBondContact O-N 3.43Å; K187-N190 PolarHBondContact O-N 2.97Å; K187-N190 VanDerWaalsContact O-N 3.1Å
188	T	95.6	Very high	96.1	Very high	57 Å²	57	75.6 Å²	75.6	35%	0.35	39%	0.391	S	S	.	.	H	α-helix	trans	-62.3	-43.6	180	-59.2	0	0	0	0	111.7	S102 V103 E184 V185 F186 N190	S102-T188 WeakPolarHBondContact O-CG2 3.39Å; V103-T188 HydrophobicContact CG2-CG2 4.38Å; E184-T188 WeakPolarHBondContact O-CB 3.23Å; E184-T188 PolarHBondContact O-N 3.25Å; E184-T188 PolarHBondContact O-OG1 3.37Å; V185-T188 WeakPolarHBondContact O-CB 3.39Å; V185-T188 PolarHBondContact O-N 3.07Å; V185-T188 VanDerWaalsContact O-N 3.17Å; F186-T188 VanDerWaalsContact C-N 3.34Å; T188-N190 PolarHBondContact O-N 2.79Å
189	Y	95.7	Very high	96.2	Very high	157 Å²	157	78.1 Å²	78.1	62%	0.616	41%	0.412	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.1	0.2	176.4	-70.7	-74.4	0	0	0	113.8	V185 F186 K187 V191	V185-Y189 HydrophobicContact CG1-CD2 3.86Å; V185-Y189 HydrophobicContact CG1-CE2 3.94Å; V185-Y189 VanDerWaalsContact O-CD2 3.27Å; V185-Y189 WeakPolarHBondContact O-CD2 3.29Å; V185-Y189 PolarHBondContact O-N 3.17Å; F186-Y189 PolarHBondContact O-N 2.81Å; K187-Y189 PolarHBondContact O-N 3.43Å; Y189-V191 PolarHBondContact O-N 3.15Å
190	N	96.3	Very high	96.2	Very high	152 Å²	152	78 Å²	78	81%	0.813	42%	0.416	S	S	*	.	T	Hydrogen-bonded Turn	trans	50.9	41	-177.6	-161.7	20.9	0	0	0	113.3	F186 K187 T188	F186-N190 PolarHBondContact O-N 3.07Å; K187-N190 PolarHBondContact O-N 2.97Å; K187-N190 VanDerWaalsContact O-N 3.1Å; T188-N190 PolarHBondContact O-N 2.79Å
191	V	96.2	Very high	96.3	Very high	79 Å²	79	79.9 Å²	79.9	48%	0.479	43%	0.426	S	S	.	.			trans	-99.2	126.1	-179.8	-179.1	0	0	0	0	109.5	F186 Y189 V193	F186-V191 PolarHBondContact O-N 3.1Å; F186-V191 VanDerWaalsContact O-N 3.08Å; Y189-V191 PolarHBondContact O-N 3.15Å; V191-V193 HydrophobicContact CB-CG2 4.49Å; V191-V193 HydrophobicContact CG1-CG2 3.81Å; V191-V193 PolarHBondContact O-N 3.3Å
192	A	95.8	Very high	96.4	Very high	107 Å²	107	78.2 Å²	78.2	88%	0.884	42%	0.42	S	S	*	.			trans	-77.9	113.3	171.2	0	0	0	0	0	109.9
193	V	95.9	Very high	96.5	Very high	49 Å²	49	84 Å²	84	30%	0.297	44%	0.44	S	S	.	.			trans	-120.4	134.9	176.1	-174.4	0	0	0	0	108.5	F186 V191 T197 V198	F186-V193 HydrophobicContact CD1-CG2 3.8Å; F186-V193 HydrophobicContact CD2-CB 4.21Å; F186-V193 HydrophobicContact CD2-CG2 3.98Å; F186-V193 HydrophobicContact CE1-CG2 3.85Å; F186-V193 HydrophobicContact CE2-CB 4.19Å; F186-V193 HydrophobicContact CE2-CG1 4.13Å; F186-V193 HydrophobicContact CE2-CG2 3.99Å; F186-V193 HydrophobicContact CG-CG2 3.89Å; F186-V193 HydrophobicContact CZ-CG1 4.36Å; F186-V193 HydrophobicContact CZ-CG2 3.94Å; V191-V193 HydrophobicContact CB-CG2 4.49Å; V191-V193 HydrophobicContact CG1-CG2 3.81Å; V191-V193 PolarHBondContact O-N 3.3Å; V193-T197 HydrophobicContact CG1-CG2 3.79Å; V193-V198 HydrophobicContact CB-CG2 4.41Å; V193-V198 HydrophobicContact CG1-CG2 3.84Å
194	D	96.4	Very high	96.6	Very high	81 Å²	81	86.8 Å²	86.8	43%	0.433	45%	0.449	S	S	.	.			trans	-76.8	156.7	179.4	67.8	-64.5	0	0	0	112.2	I196 T197 V198	D194-I196 VanDerWaalsContact C-N 3.26Å; D194-I196 PolarHBondContact O-N 3.08Å; D194-I196 VanDerWaalsContact OD2-CB 3.3Å; D194-I196 WeakPolarHBondContact OD2-CB 3.44Å; D194-I196 PolarHBondContact OD2-N 3.49Å; D194-T197 PolarHBondContact O-N 2.87Å; D194-T197 VanDerWaalsContact OD1-CB 3.23Å; D194-T197 WeakPolarHBondContact OD1-CB 3.4Å; D194-T197 PolarHBondContact OD1-OG1 2.89Å; D194-T197 PolarHBondContact OD2-N 3.29Å; D194-T197 VanDerWaalsContact OD2-N 3.11Å; D194-T197 PolarHBondContact OD2-OG1 3.44Å; D194-V198 PolarHBondContact O-N 3.44Å
195	Y	96.5	Very high	96.7	Very high	206 Å²	206	88 Å²	88	81%	0.808	45%	0.454	S	S	*	.	H	α-helix	trans	-62.9	-29.7	-178.7	-70.3	-69.9	0	0	0	113.8	V198 A199	Y195-V198 PolarHBondContact O-N 2.91Å; Y195-A199 WeakPolarHBondContact O-CB 3.28Å; Y195-A199 PolarHBondContact O-N 2.95Å
196	I	97.2	Very high	96.7	Very high	133 Å²	133	86.8 Å²	86.8	68%	0.682	45%	0.447	S	S	*	.	H	α-helix	trans	-68	-45	-179.1	-53.8	-59.4	0	0	0	109.6	D194 A199 L200	D194-I196 VanDerWaalsContact C-N 3.26Å; D194-I196 PolarHBondContact O-N 3.08Å; D194-I196 VanDerWaalsContact OD2-CB 3.3Å; D194-I196 WeakPolarHBondContact OD2-CB 3.44Å; D194-I196 PolarHBondContact OD2-N 3.49Å; I196-A199 PolarHBondContact O-N 2.89Å; I196-L200 WeakPolarHBondContact O-CB 3.33Å; I196-L200 PolarHBondContact O-N 3.03Å
197	T	97	Very high	96.7	Very high	54 Å²	54	86.5 Å²	86.5	33%	0.331	45%	0.449	S	S	.	.	H	α-helix	trans	-59.2	-49.6	174.3	-60.7	0	0	0	0	111.7	V193 D194 A199 L200 L201	V193-T197 HydrophobicContact CG1-CG2 3.79Å; D194-T197 PolarHBondContact O-N 2.87Å; D194-T197 VanDerWaalsContact OD1-CB 3.23Å; D194-T197 WeakPolarHBondContact OD1-CB 3.4Å; D194-T197 PolarHBondContact OD1-OG1 2.89Å; D194-T197 PolarHBondContact OD2-N 3.29Å; D194-T197 VanDerWaalsContact OD2-N 3.11Å; D194-T197 PolarHBondContact OD2-OG1 3.44Å; T197-A199 PolarHBondContact O-N 3.25Å; T197-L200 PolarHBondContact O-N 3.28Å; T197-L201 HydrophobicContact CG2-CD1 3.99Å; T197-L201 VanDerWaalsContact O-CD1 3.3Å; T197-L201 WeakPolarHBondContact O-CD1 3.45Å; T197-L201 PolarHBondContact O-N 3.34Å
198	V	97.2	Very high	96.8	Very high	19 Å²	19	82.9 Å²	82.9	12%	0.115	44%	0.438	C	S	.	.	H	α-helix	trans	-61.4	-45.3	179.7	178.1	0	0	0	0	111.5	F179 L182 F186 V193 D194 Y195 L200 L201 I202	F179-V198 HydrophobicContact CD2-CG1 3.91Å; F179-V198 HydrophobicContact CE2-CG1 3.82Å; L182-V198 HydrophobicContact CD2-CG1 4.48Å; F186-V198 HydrophobicContact CD2-CG2 4.5Å; F186-V198 HydrophobicContact CE2-CG2 4.1Å; V193-V198 HydrophobicContact CB-CG2 4.41Å; V193-V198 HydrophobicContact CG1-CG2 3.84Å; D194-V198 PolarHBondContact O-N 3.44Å; Y195-V198 PolarHBondContact O-N 2.91Å; V198-L200 VanDerWaalsContact C-N 3.34Å; V198-L200 PolarHBondContact O-N 3.4Å; V198-L201 PolarHBondContact O-N 3.23Å; V198-I202 HydrophobicContact CG1-CG1 4.19Å; V198-I202 WeakPolarHBondContact O-CB 3.29Å; V198-I202 WeakPolarHBondContact O-CG1 3.46Å; V198-I202 PolarHBondContact O-N 2.72Å
199	A	96.8	Very high	96.7	Very high	61 Å²	61	80.2 Å²	80.2	50%	0.504	42%	0.421	S	S	.	.	H	α-helix	trans	-60.8	-44	179	0	0	0	0	0	111.6	Y195 I196 T197 W203	Y195-A199 WeakPolarHBondContact O-CB 3.28Å; Y195-A199 PolarHBondContact O-N 2.95Å; I196-A199 PolarHBondContact O-N 2.89Å; T197-A199 PolarHBondContact O-N 3.25Å; A199-W203 WeakPolarHBondContact O-CB 3.46Å; A199-W203 PolarHBondContact O-N 3.5Å
200	L	97.5	Very high	96.7	Very high	102 Å²	102	74 Å²	74	53%	0.534	40%	0.398	S	S	.	.	H	α-helix	trans	-65.4	-42.7	178.4	-171.8	69.4	0	0	0	111.9	I196 T197 V198 N204	I196-L200 WeakPolarHBondContact O-CB 3.33Å; I196-L200 PolarHBondContact O-N 3.03Å; T197-L200 PolarHBondContact O-N 3.28Å; V198-L200 VanDerWaalsContact C-N 3.34Å; V198-L200 PolarHBondContact O-N 3.4Å; L200-N204 WeakPolarHBondContact O-CB 3.41Å; L200-N204 PolarHBondContact O-N 3.45Å; L200-N204 PolarHBondContact O-ND2 2.83Å
201	L	97.3	Very high	96.6	Very high	78 Å²	78	70.8 Å²	70.8	41%	0.408	38%	0.38	S	S	.	.	H	α-helix	trans	-64.5	-50	178.6	-96.6	65.3	0	0	0	111.6	L182 T197 V198 W203 N204 F205	L182-L201 HydrophobicContact CD2-CB 4.41Å; L182-L201 HydrophobicContact CD2-CD2 4.38Å; T197-L201 HydrophobicContact CG2-CD1 3.99Å; T197-L201 VanDerWaalsContact O-CD1 3.3Å; T197-L201 WeakPolarHBondContact O-CD1 3.45Å; T197-L201 PolarHBondContact O-N 3.34Å; V198-L201 PolarHBondContact O-N 3.23Å; L201-W203 VanDerWaalsContact C-N 3.34Å; L201-W203 PolarHBondContact O-N 3.34Å; L201-N204 PolarHBondContact O-N 2.92Å; L201-F205 VanDerWaalsContact O-CB 3.31Å; L201-F205 WeakPolarHBondContact O-CB 3.21Å; L201-F205 PolarHBondContact O-N 3.18Å
202	I	97.4	Very high	96.4	Very high	17 Å²	17	67.2 Å²	67.2	9%	0.087	36%	0.359	C	S	.	.	H	α-helix	trans	-66	-38	-179.8	-66.1	-62	0	0	0	111.3	F175 F179 L182 V198 G206	F175-I202 HydrophobicContact CD1-CG2 4.15Å; F179-I202 HydrophobicContact CB-CD1 4.36Å; F179-I202 HydrophobicContact CB-CG1 4.38Å; F179-I202 HydrophobicContact CD2-CG1 4.35Å; L182-I202 HydrophobicContact CB-CD1 4.31Å; L182-I202 HydrophobicContact CD2-CD1 3.85Å; L182-I202 HydrophobicContact CD2-CG1 4.16Å; V198-I202 HydrophobicContact CG1-CG1 4.19Å; V198-I202 WeakPolarHBondContact O-CB 3.29Å; V198-I202 WeakPolarHBondContact O-CG1 3.46Å; V198-I202 PolarHBondContact O-N 2.72Å; I202-G206 PolarHBondContact O-N 2.99Å
203	W	97.8	Very high	96.2	Very high	155 Å²	155	62.2 Å²	62.2	59%	0.587	32%	0.317	S	S	*	.	H	α-helix	trans	-60.2	-50.8	174	176.8	-101.7	0	0	0	111.8	F175 A199 L201 G206 V207	F175-W203 HydrophobicContact CE1-CE3 4.16Å; A199-W203 WeakPolarHBondContact O-CB 3.46Å; A199-W203 PolarHBondContact O-N 3.5Å; L201-W203 VanDerWaalsContact C-N 3.34Å; L201-W203 PolarHBondContact O-N 3.34Å; W203-G206 PolarHBondContact O-N 3.49Å; W203-V207 HydrophobicContact CD2-CG2 3.8Å; W203-V207 HydrophobicContact CE3-CG2 4.04Å; W203-V207 HydrophobicContact CG-CG2 4.4Å; W203-V207 HydrophobicContact CH2-CG2 3.99Å; W203-V207 HydrophobicContact CZ2-CG2 3.74Å; W203-V207 HydrophobicContact CZ3-CG2 4.13Å; W203-V207 WeakPolarHBondContact O-CB 3.42Å; W203-V207 VanDerWaalsContact O-CG2 3.28Å; W203-V207 WeakPolarHBondContact O-CG2 3.42Å; W203-V207 PolarHBondContact O-N 3.47Å
204	N	97.9	Very high	96	Very high	81 Å²	81	62.4 Å²	62.4	43%	0.433	32%	0.315	S	S	.	.	H	α-helix	trans	-61.7	-46.8	178.2	-77.6	-56.6	0	0	0	111.7	L200 L201 V208	L200-N204 WeakPolarHBondContact O-CB 3.41Å; L200-N204 PolarHBondContact O-N 3.45Å; L200-N204 PolarHBondContact O-ND2 2.83Å; L201-N204 PolarHBondContact O-N 2.92Å; N204-V208 VanDerWaalsContact O-CB 3.23Å; N204-V208 WeakPolarHBondContact O-CB 3.35Å; N204-V208 WeakPolarHBondContact O-CG2 3.5Å; N204-V208 PolarHBondContact O-N 2.82Å
205	F	97.3	Very high	95.6	Very high	54 Å²	54	67.7 Å²	67.7	24%	0.237	33%	0.329	C	S	.	.	H	α-helix	trans	-60.3	-47.8	178.2	-178.7	-97.1	0	0	0	111.9	L174 S178 L201 G209 Y225	L174-F205 HydrophobicContact CD2-CD1 4.46Å; L174-F205 HydrophobicContact CD2-CE1 3.68Å; L174-F205 HydrophobicContact CD2-CZ 4.18Å; S178-F205 WeakPolarHBondContact OG-CE1 3.28Å; L201-F205 VanDerWaalsContact O-CB 3.31Å; L201-F205 WeakPolarHBondContact O-CB 3.21Å; L201-F205 PolarHBondContact O-N 3.18Å; F205-G209 PolarHBondContact O-N 2.85Å; F205-Y225 AromaticContact CD2-CE1 3.83Å; F205-Y225 HydrophobicContact CD2-CE1 3.83Å; F205-Y225 HydrophobicContact CE1-CE1 4.27Å; F205-Y225 HydrophobicContact CE2-CD1 4.19Å; F205-Y225 AromaticContact CE2-CE1 3.55Å; F205-Y225 HydrophobicContact CE2-CE1 3.55Å; F205-Y225 HydrophobicContact CG-CE1 4.32Å; F205-Y225 HydrophobicContact CZ-CD1 4.11Å; F205-Y225 AromaticContact CZ-CE1 3.79Å; F205-Y225 HydrophobicContact CZ-CE1 3.79Å; F205-Y225 WeakPolarHBondContact O-CE1 3.25Å; F205-Y225 PolarHBondContact O-OH 3.37Å
206	G	96.7	Very high	95.2	Very high	0 Å²	0	66.7 Å²	66.7	0%	0	33%	0.328	C	S	.	.	H	α-helix	trans	-66.6	-48.5	-178.7	0	0	0	0	0	112.8	F175 I202 W203 G209 M210	F175-G206 VanDerWaalsContact CZ-C 3.48Å; I202-G206 PolarHBondContact O-N 2.99Å; W203-G206 PolarHBondContact O-N 3.49Å; G206-G209 PolarHBondContact O-N 3.28Å; G206-M210 VanDerWaalsContact O-CG 3.27Å; G206-M210 WeakPolarHBondContact O-CG 3.41Å; G206-M210 PolarHBondContact O-N 2.87Å
207	V	96.8	Very high	94.6	Very high	43 Å²	43	61.9 Å²	61.9	26%	0.261	31%	0.312	S	S	.	.	H	α-helix	trans	-66.8	-46.4	-178.7	174.1	0	0	0	0	111.4	F175 W203 G209 M210 I211	F175-V207 HydrophobicContact CZ-CG2 4.12Å; W203-V207 HydrophobicContact CD2-CG2 3.8Å; W203-V207 HydrophobicContact CE3-CG2 4.04Å; W203-V207 HydrophobicContact CG-CG2 4.4Å; W203-V207 HydrophobicContact CH2-CG2 3.99Å; W203-V207 HydrophobicContact CZ2-CG2 3.74Å; W203-V207 HydrophobicContact CZ3-CG2 4.13Å; W203-V207 WeakPolarHBondContact O-CB 3.42Å; W203-V207 VanDerWaalsContact O-CG2 3.28Å; W203-V207 WeakPolarHBondContact O-CG2 3.42Å; W203-V207 PolarHBondContact O-N 3.47Å; V207-G209 VanDerWaalsContact C-N 3.29Å; V207-G209 PolarHBondContact O-N 2.89Å; V207-M210 PolarHBondContact O-N 2.91Å; V207-I211 HydrophobicContact CG1-CD1 3.85Å; V207-I211 HydrophobicContact CG1-CG1 4.48Å; V207-I211 WeakPolarHBondContact O-CG1 3.47Å; V207-I211 PolarHBondContact O-N 3.24Å
208	V	96.6	Very high	94.3	Very high	56 Å²	56	63.3 Å²	63.3	34%	0.339	32%	0.322	S	S	.	.	H	α-helix	trans	-64.5	-37.5	178	175.9	0	0	0	0	110.6	N204 I211 S212 L221 Y225	N204-V208 VanDerWaalsContact O-CB 3.23Å; N204-V208 WeakPolarHBondContact O-CB 3.35Å; N204-V208 WeakPolarHBondContact O-CG2 3.5Å; N204-V208 PolarHBondContact O-N 2.82Å; V208-I211 PolarHBondContact O-N 3.46Å; V208-S212 VanDerWaalsContact O-CB 3.28Å; V208-S212 WeakPolarHBondContact O-CB 3.31Å; V208-S212 PolarHBondContact O-N 3.3Å; V208-S212 PolarHBondContact O-OG 3.14Å; V208-L221 HydrophobicContact CG1-CD2 3.88Å; V208-Y225 HydrophobicContact CG1-CE2 3.96Å; V208-Y225 WeakPolarHBondContact CG1-OH 3.48Å
209	G	95.4	Very high	93.9	Very high	0 Å²	0	64.4 Å²	64.4	0%	0	33%	0.327	C	S	.	.	H	α-helix	trans	-62.1	-44.9	173.2	0	0	0	0	0	112.7	F205 G206 V207 S212 I213 Y225	F205-G209 PolarHBondContact O-N 2.85Å; G206-G209 PolarHBondContact O-N 3.28Å; V207-G209 VanDerWaalsContact C-N 3.29Å; V207-G209 PolarHBondContact O-N 2.89Å; G209-S212 PolarHBondContact O-N 3.32Å; G209-I213 WeakPolarHBondContact O-CB 3.45Å; G209-I213 VanDerWaalsContact O-CG1 3.29Å; G209-I213 WeakPolarHBondContact O-CG1 3.24Å; G209-I213 PolarHBondContact O-N 3.07Å; G209-Y225 VanDerWaalsContact CA-CE1 3.41Å; G209-Y225 VanDerWaalsContact CA-CZ 3.48Å
210	M	94.6	Very high	93.6	Very high	26 Å²	26	68.8 Å²	68.8	13%	0.128	33%	0.331	C	S	.	.	H	α-helix	trans	-62.8	-44.1	177	-71.5	-57.4	-66.8	0	0	112.3	I167 L171 L174 F175 G206 V207 I213 H214	I167-M210 HydrophobicContact CB-CE 4.46Å; I167-M210 HydrophobicContact CD1-CE 3.64Å; I167-M210 HydrophobicContact CG2-CE 3.93Å; L171-M210 HydrophobicContact CD2-CE 3.85Å; L171-M210 HydrophobicContact CD2-CG 3.71Å; L171-M210 HydrophobicContact CD2-SD 3.79Å; L171-M210 HydrophobicContact CG-CE 3.79Å; L171-M210 HydrophobicContact CG-SD 4.04Å; L174-M210 HydrophobicContact CD1-CG 4.19Å; L174-M210 HydrophobicContact CD1-SD 3.95Å; F175-M210 HydrophobicContact CE2-CG 4.21Å; G206-M210 VanDerWaalsContact O-CG 3.27Å; G206-M210 WeakPolarHBondContact O-CG 3.41Å; G206-M210 PolarHBondContact O-N 2.87Å; V207-M210 PolarHBondContact O-N 2.91Å; M210-I213 PolarHBondContact O-N 2.94Å; M210-H214 WeakPolarHBondContact O-CB 2.98Å; M210-H214 PolarHBondContact O-N 3.39Å
211	I	94.3	Very high	93.4	Very high	86 Å²	86	66.9 Å²	66.9	44%	0.441	32%	0.321	S	S	.	.	H	α-helix	trans	-62.8	-43.6	175.4	-66	168.4	0	0	0	110.2	V207 V208 I213 W215	V207-I211 HydrophobicContact CG1-CD1 3.85Å; V207-I211 HydrophobicContact CG1-CG1 4.48Å; V207-I211 WeakPolarHBondContact O-CG1 3.47Å; V207-I211 PolarHBondContact O-N 3.24Å; V208-I211 PolarHBondContact O-N 3.46Å; I211-I213 VanDerWaalsContact C-N 3.35Å; I211-I213 PolarHBondContact O-N 3.49Å; I211-W215 HydrophobicContact CG2-CB 4.24Å; I211-W215 CarbonylContact O-C 3.21Å; I211-W215 VanDerWaalsContact O-CA 3.23Å; I211-W215 WeakPolarHBondContact O-CA 3.13Å; I211-W215 WeakPolarHBondContact O-CB 3.34Å; I211-W215 PolarHBondContact O-N 2.87Å; I211-W215 VanDerWaalsContact O-O 3.09Å
212	S	92.2	Very high	93.1	Very high	3 Å²	3	65.3 Å²	65.3	2%	0.021	31%	0.311	C	S	.	.	H	α-helix	trans	-68.9	-29.9	-177	-57.6	0	0	0	0	113.7	V208 G209 L221 Q222	V208-S212 VanDerWaalsContact O-CB 3.28Å; V208-S212 WeakPolarHBondContact O-CB 3.31Å; V208-S212 PolarHBondContact O-N 3.3Å; V208-S212 PolarHBondContact O-OG 3.14Å; G209-S212 PolarHBondContact O-N 3.32Å; S212-L221 WeakPolarHBondContact OG-CD2 3.28Å; S212-Q222 WeakPolarHBondContact O-CG 3.38Å
213	I	91.5	Very high	92.9	Very high	3 Å²	3	65 Å²	65	2%	0.015	31%	0.31	C	S	.	.	H	α-helix	trans	-92.5	-44.5	-176.7	-64.4	168.1	0	0	0	112.2	L174 G209 M210 I211 I229 A285	L174-I213 HydrophobicContact CD1-CD1 4.18Å; G209-I213 WeakPolarHBondContact O-CB 3.45Å; G209-I213 VanDerWaalsContact O-CG1 3.29Å; G209-I213 WeakPolarHBondContact O-CG1 3.24Å; G209-I213 PolarHBondContact O-N 3.07Å; M210-I213 PolarHBondContact O-N 2.94Å; I211-I213 VanDerWaalsContact C-N 3.35Å; I211-I213 PolarHBondContact O-N 3.49Å; I213-I229 HydrophobicContact CD1-CD1 3.32Å; I213-A285 HydrophobicContact CG2-CB 3.64Å
214	H	90.8	Very high	92.7	Very high	52 Å²	52	59.9 Å²	59.9	24%	0.241	30%	0.3	C	S	.	.	H	α-helix	trans	-101.3	-16.4	-172.5	-65.4	90.1	0	0	0	113.4	I167 S170 M210	I167-H214 HydrophobicContact CD1-CB 3.91Å; I167-H214 WeakPolarHBondContact CD1-CD2 3.49Å; S170-H214 PolarHBondContact OG-CE1 3.36Å; M210-H214 WeakPolarHBondContact O-CB 2.98Å; M210-H214 PolarHBondContact O-N 3.39Å
215	W	89.8	Confident	92.6	Very high	192 Å²	192	57 Å²	57	73%	0.727	28%	0.283	S	S	*	.	S	Bend	trans	-117.3	179.8	175.5	-154.6	-95.2	0	0	0	110.5	I211 G217	I211-W215 HydrophobicContact CG2-CB 4.24Å; I211-W215 CarbonylContact O-C 3.21Å; I211-W215 VanDerWaalsContact O-CA 3.23Å; I211-W215 WeakPolarHBondContact O-CA 3.13Å; I211-W215 WeakPolarHBondContact O-CB 3.34Å; I211-W215 PolarHBondContact O-N 2.87Å; I211-W215 VanDerWaalsContact O-O 3.09Å; W215-G217 PolarHBondContact O-N 2.9Å
216	K	87.7	Confident	92.5	Very high	185 Å²	185	54.5 Å²	54.5	80%	0.804	27%	0.272	S	S	*	.			trans	-66.8	124.6	172.7	-61.7	-175.6	178.4	75.4	0	109.4
217	G	84.6	Confident	92.4	Very high	33 Å²	33	55.3 Å²	55.3	34%	0.34	28%	0.277	S	S	.	.			trans	-147.3	169.4	175.7	0	0	0	0	0	111.9	W215 L219	W215-G217 PolarHBondContact O-N 2.9Å; G217-L219 PolarHBondContact O-N 3.46Å
218	P	91	Very high	92.3	Very high	84 Å²	84	55.9 Å²	55.9	55%	0.545	28%	0.277	S	S	.	.			trans	-67.3	133.3	176.6	23	-26.2	0	0	0	110.4	R220 L221 Q222	P218-R220 VanDerWaalsContact C-N 3.29Å; P218-R220 PolarHBondContact O-N 3.32Å; P218-L221 HydrophobicContact CB-CB 4.48Å; P218-L221 HydrophobicContact CG-CB 3.74Å; P218-L221 HydrophobicContact CG-CD2 3.98Å; P218-L221 WeakPolarHBondContact O-CB 3.34Å; P218-L221 PolarHBondContact O-N 3.44Å; P218-Q222 PolarHBondContact O-N 3.18Å; P218-Q222 VanDerWaalsContact O-N 3.08Å
219	L	87.5	Confident	92.3	Very high	41 Å²	41	53.8 Å²	53.8	22%	0.215	26%	0.264	C	S	.	.	H	α-helix	trans	-56.5	-39.8	-171.9	178.9	143	0	0	0	113.7	G217 L221 Q222 Q223 T291	G217-L219 PolarHBondContact O-N 3.46Å; L219-L221 VanDerWaalsContact C-N 3.31Å; L219-L221 PolarHBondContact O-N 2.9Å; L219-Q222 PolarHBondContact O-N 3.1Å; L219-Q223 VanDerWaalsContact CD2-CD 3.48Å; L219-Q223 HydrophobicContact CD2-CG 4.24Å; L219-Q223 VanDerWaalsContact O-CG 3.31Å; L219-Q223 WeakPolarHBondContact O-CG 3.33Å; L219-Q223 PolarHBondContact O-N 3.46Å; L219-T291 WeakPolarHBondContact CD1-O 3.45Å
220	R	90.6	Very high	92.3	Very high	154 Å²	154	53.9 Å²	53.9	58%	0.581	26%	0.264	S	S	*	.	H	α-helix	trans	-64.9	-36.3	178.4	-64.7	-57.1	-171.2	179.8	6.8	112.4	P218 Q223 A224 M292	P218-R220 VanDerWaalsContact C-N 3.29Å; P218-R220 PolarHBondContact O-N 3.32Å; R220-Q223 VanDerWaalsContact NH1-OE1 3.08Å; R220-Q223 PolarHBondContact O-N 3.22Å; R220-A224 WeakPolarHBondContact O-CB 3.24Å; R220-A224 PolarHBondContact O-N 3.26Å; R220-M292 VanDerWaalsContact NH2-CE 3.33Å
221	L	93	Very high	92.4	Very high	62 Å²	62	52.7 Å²	52.7	33%	0.325	26%	0.259	S	S	.	.	H	α-helix	trans	-71	-42.5	178	-169.7	61	0	0	0	110.6	V208 S212 P218 L219 Q223 A224 Y225	V208-L221 HydrophobicContact CG1-CD2 3.88Å; S212-L221 WeakPolarHBondContact OG-CD2 3.28Å; P218-L221 HydrophobicContact CB-CB 4.48Å; P218-L221 HydrophobicContact CG-CB 3.74Å; P218-L221 HydrophobicContact CG-CD2 3.98Å; P218-L221 WeakPolarHBondContact O-CB 3.34Å; P218-L221 PolarHBondContact O-N 3.44Å; L219-L221 VanDerWaalsContact C-N 3.31Å; L219-L221 PolarHBondContact O-N 2.9Å; L221-Q223 VanDerWaalsContact C-N 3.34Å; L221-Q223 PolarHBondContact O-N 3.33Å; L221-A224 PolarHBondContact O-N 3.44Å; L221-Y225 HydrophobicContact CD1-CD2 4.07Å; L221-Y225 HydrophobicContact CD1-CE2 3.66Å; L221-Y225 HydrophobicContact CD2-CE2 4.32Å; L221-Y225 HydrophobicContact CG-CD2 3.92Å; L221-Y225 HydrophobicContact CG-CE2 3.72Å; L221-Y225 VanDerWaalsContact O-CD2 3.27Å; L221-Y225 WeakPolarHBondContact O-CD2 3.46Å; L221-Y225 PolarHBondContact O-N 2.91Å
222	Q	92.2	Very high	92.5	Very high	44 Å²	44	48.9 Å²	48.9	21%	0.206	24%	0.239	C	C	.	.	H	α-helix	trans	-57.1	-47.6	172.4	-174.9	-177.5	-7.6	0	0	111.1	S212 P218 L219 A224 Y225 L226	S212-Q222 WeakPolarHBondContact O-CG 3.38Å; P218-Q222 PolarHBondContact O-N 3.18Å; P218-Q222 VanDerWaalsContact O-N 3.08Å; L219-Q222 PolarHBondContact O-N 3.1Å; Q222-A224 VanDerWaalsContact C-N 3.35Å; Q222-A224 PolarHBondContact O-N 3.47Å; Q222-Y225 PolarHBondContact O-N 2.95Å; Q222-L226 HydrophobicContact CG-CD1 4.06Å; Q222-L226 VanDerWaalsContact O-CG 3.24Å; Q222-L226 WeakPolarHBondContact O-CG 3.33Å; Q222-L226 PolarHBondContact O-N 3.43Å
223	Q	92.5	Very high	92.6	Very high	12 Å²	12	50.8 Å²	50.8	6%	0.056	25%	0.248	C	C	.	.	H	α-helix	trans	-59.1	-43.1	176	-72.4	179.1	-17.4	0	0	112.4	L219 R220 L221 L226 I227 Y288 S289	L219-Q223 VanDerWaalsContact CD2-CD 3.48Å; L219-Q223 HydrophobicContact CD2-CG 4.24Å; L219-Q223 VanDerWaalsContact O-CG 3.31Å; L219-Q223 WeakPolarHBondContact O-CG 3.33Å; L219-Q223 PolarHBondContact O-N 3.46Å; R220-Q223 VanDerWaalsContact NH1-OE1 3.08Å; R220-Q223 PolarHBondContact O-N 3.22Å; L221-Q223 VanDerWaalsContact C-N 3.34Å; L221-Q223 PolarHBondContact O-N 3.33Å; Q223-L226 PolarHBondContact O-N 2.9Å; Q223-I227 VanDerWaalsContact O-CG1 3.29Å; Q223-I227 WeakPolarHBondContact O-CG1 3.18Å; Q223-I227 PolarHBondContact O-N 3.44Å; Q223-Y288 HydrophobicContact CB-CE2 3.72Å; Q223-Y288 HydrophobicContact CG-CD2 4.44Å; Q223-Y288 HydrophobicContact CG-CE2 3.58Å; Q223-Y288 PolarHBondContact NE2-OH 3.4Å; Q223-Y288 PolarHBondContact OE1-OH 3.12Å; Q223-S289 PolarHBondContact NE2-O 3.48Å
224	A	94.7	Very high	92.8	Very high	46 Å²	46	50.7 Å²	50.7	38%	0.38	25%	0.248	S	C	.	.	H	α-helix	trans	-62.1	-45.5	177.3	0	0	0	0	0	112.1	R220 L221 Q222 L226 I227 M228	R220-A224 WeakPolarHBondContact O-CB 3.24Å; R220-A224 PolarHBondContact O-N 3.26Å; L221-A224 PolarHBondContact O-N 3.44Å; Q222-A224 VanDerWaalsContact C-N 3.35Å; Q222-A224 PolarHBondContact O-N 3.47Å; A224-L226 PolarHBondContact O-N 2.91Å; A224-I227 PolarHBondContact O-N 2.73Å; A224-M228 WeakPolarHBondContact O-CG 3.43Å; A224-M228 PolarHBondContact O-N 3.44Å
225	Y	95.3	Very high	93.1	Very high	20 Å²	20	48.3 Å²	48.3	8%	0.078	24%	0.237	C	C	.	.	H	α-helix	trans	-64.4	-38.4	176.2	-83.8	-73.6	0	0	0	112.7	L174 F205 V208 G209 L221 Q222 I227 M228 I229	L174-Y225 HydrophobicContact CD2-CD1 3.92Å; L174-Y225 HydrophobicContact CD2-CE1 4.35Å; F205-Y225 AromaticContact CD2-CE1 3.83Å; F205-Y225 HydrophobicContact CD2-CE1 3.83Å; F205-Y225 HydrophobicContact CE1-CE1 4.27Å; F205-Y225 HydrophobicContact CE2-CD1 4.19Å; F205-Y225 AromaticContact CE2-CE1 3.55Å; F205-Y225 HydrophobicContact CE2-CE1 3.55Å; F205-Y225 HydrophobicContact CG-CE1 4.32Å; F205-Y225 HydrophobicContact CZ-CD1 4.11Å; F205-Y225 AromaticContact CZ-CE1 3.79Å; F205-Y225 HydrophobicContact CZ-CE1 3.79Å; F205-Y225 WeakPolarHBondContact O-CE1 3.25Å; F205-Y225 PolarHBondContact O-OH 3.37Å; V208-Y225 HydrophobicContact CG1-CE2 3.96Å; V208-Y225 WeakPolarHBondContact CG1-OH 3.48Å; G209-Y225 VanDerWaalsContact CA-CE1 3.41Å; G209-Y225 VanDerWaalsContact CA-CZ 3.48Å; L221-Y225 HydrophobicContact CD1-CD2 4.07Å; L221-Y225 HydrophobicContact CD1-CE2 3.66Å; L221-Y225 HydrophobicContact CD2-CE2 4.32Å; L221-Y225 HydrophobicContact CG-CD2 3.92Å; L221-Y225 HydrophobicContact CG-CE2 3.72Å; L221-Y225 VanDerWaalsContact O-CD2 3.27Å; L221-Y225 WeakPolarHBondContact O-CD2 3.46Å; L221-Y225 PolarHBondContact O-N 2.91Å; Q222-Y225 PolarHBondContact O-N 2.95Å; Y225-I227 VanDerWaalsContact C-N 3.35Å; Y225-I227 PolarHBondContact O-N 2.91Å; Y225-M228 PolarHBondContact O-N 2.87Å; Y225-I229 WeakPolarHBondContact O-CB 3.35Å; Y225-I229 VanDerWaalsContact O-CG1 3.32Å; Y225-I229 WeakPolarHBondContact O-CG1 3.18Å; Y225-I229 PolarHBondContact O-N 3.39Å
226	L	93.8	Very high	93.3	Very high	2 Å²	2	40 Å²	40	1%	0.01	21%	0.207	C	C	.	.	H	α-helix	trans	-63.8	-39.7	176	-70	169.6	0	0	0	111.9	Q222 Q223 A224 S230 Y288 L325	Q222-L226 HydrophobicContact CG-CD1 4.06Å; Q222-L226 VanDerWaalsContact O-CG 3.24Å; Q222-L226 WeakPolarHBondContact O-CG 3.33Å; Q222-L226 PolarHBondContact O-N 3.43Å; Q223-L226 PolarHBondContact O-N 2.9Å; A224-L226 PolarHBondContact O-N 2.91Å; L226-S230 WeakPolarHBondContact O-CB 3.37Å; L226-S230 PolarHBondContact O-N 3.24Å; L226-S230 PolarHBondContact O-OG 2.9Å; L226-Y288 HydrophobicContact CB-CD2 4.39Å; L226-Y288 HydrophobicContact CD1-CD2 4.26Å; L226-L325 HydrophobicContact CB-CD2 3.98Å; L226-L325 HydrophobicContact CD2-CD1 3.73Å; L226-L325 HydrophobicContact CD2-CD2 4.06Å; L226-L325 HydrophobicContact CD2-CG 4.39Å; L226-L325 HydrophobicContact CG-CD2 4.47Å
227	I	95.5	Very high	93.5	Very high	18 Å²	18	32.9 Å²	32.9	9%	0.092	18%	0.176	C	C	.	.	H	α-helix	trans	-63.6	-46.2	173.6	-67.6	164.9	0	0	0	110.4	P88 L91 C92 Q223 A224 Y225 S230 A231	P88-I227 HydrophobicContact CB-CD1 3.73Å; P88-I227 HydrophobicContact CB-CG1 4.09Å; L91-I227 HydrophobicContact CB-CG2 4.46Å; C92-I227 HydrophobicContact CB-CG2 3.95Å; Q223-I227 VanDerWaalsContact O-CG1 3.29Å; Q223-I227 WeakPolarHBondContact O-CG1 3.18Å; Q223-I227 PolarHBondContact O-N 3.44Å; A224-I227 PolarHBondContact O-N 2.73Å; Y225-I227 VanDerWaalsContact C-N 3.35Å; Y225-I227 PolarHBondContact O-N 2.91Å; I227-S230 PolarHBondContact O-N 3.49Å; I227-A231 WeakPolarHBondContact O-CB 3.32Å; I227-A231 PolarHBondContact O-N 3.36Å
228	M	95.2	Very high	94	Very high	54 Å²	54	31.7 Å²	31.7	27%	0.266	16%	0.162	S	C	.	.	H	α-helix	trans	-63.5	-43.8	179	-72.5	-59.4	-60.6	0	0	112.6	A224 Y225 S230 A231 L232	A224-M228 WeakPolarHBondContact O-CG 3.43Å; A224-M228 PolarHBondContact O-N 3.44Å; Y225-M228 PolarHBondContact O-N 2.87Å; M228-S230 VanDerWaalsContact C-N 3.31Å; M228-S230 PolarHBondContact O-N 2.96Å; M228-A231 PolarHBondContact O-N 2.92Å; M228-L232 WeakPolarHBondContact O-CG 3.34Å; M228-L232 PolarHBondContact O-N 2.96Å
229	I	95.2	Very high	94	Very high	13 Å²	13	28.3 Å²	28.3	7%	0.067	14%	0.139	C	C	.	.	H	α-helix	trans	-62.1	-41.8	175.9	-73.4	172.9	0	0	0	110.6	L173 L174 I213 Y225 A231 L232 M233	L173-I229 HydrophobicContact CD1-CG2 4.02Å; L174-I229 HydrophobicContact CD1-CD1 4.4Å; L174-I229 HydrophobicContact CD2-CD1 3.87Å; L174-I229 HydrophobicContact CD2-CG1 3.77Å; L174-I229 HydrophobicContact CG-CD1 4.04Å; L174-I229 HydrophobicContact CG-CG1 4.3Å; I213-I229 HydrophobicContact CD1-CD1 3.32Å; Y225-I229 WeakPolarHBondContact O-CB 3.35Å; Y225-I229 VanDerWaalsContact O-CG1 3.32Å; Y225-I229 WeakPolarHBondContact O-CG1 3.18Å; Y225-I229 PolarHBondContact O-N 3.39Å; I229-A231 VanDerWaalsContact C-N 3.35Å; I229-L232 PolarHBondContact O-N 3.23Å; I229-M233 WeakPolarHBondContact O-CB 3.43Å; I229-M233 WeakPolarHBondContact O-CG 3.24Å; I229-M233 PolarHBondContact O-N 2.87Å
230	S	95.8	Very high	94.2	Very high	1 Å²	1	29.5 Å²	29.5	1%	0.007	14%	0.141	C	C	.	.	H	α-helix	trans	-63.9	-41.8	177.2	-56.3	0	0	0	0	111.4	L226 I227 M228 M233 A234	L226-S230 WeakPolarHBondContact O-CB 3.37Å; L226-S230 PolarHBondContact O-N 3.24Å; L226-S230 PolarHBondContact O-OG 2.9Å; I227-S230 PolarHBondContact O-N 3.49Å; M228-S230 VanDerWaalsContact C-N 3.31Å; M228-S230 PolarHBondContact O-N 2.96Å; S230-M233 PolarHBondContact O-N 3.39Å; S230-A234 WeakPolarHBondContact O-CB 3.4Å; S230-A234 PolarHBondContact O-N 2.95Å
231	A	97	Very high	94.2	Very high	2 Å²	2	22.7 Å²	22.7	2%	0.017	12%	0.116	C	C	.	.	H	α-helix	trans	-64.6	-45.2	175.8	0	0	0	0	0	112	V95 V96 I227 M228 I229 A234 L235	V95-A231 HydrophobicContact CB-CB 4.37Å; V95-A231 HydrophobicContact CG1-CB 3.82Å; V96-A231 HydrophobicContact CG2-CB 3.7Å; I227-A231 WeakPolarHBondContact O-CB 3.32Å; I227-A231 PolarHBondContact O-N 3.36Å; M228-A231 PolarHBondContact O-N 2.92Å; I229-A231 VanDerWaalsContact C-N 3.35Å; A231-A234 PolarHBondContact O-N 2.88Å; A231-L235 VanDerWaalsContact O-CG 3.3Å; A231-L235 WeakPolarHBondContact O-CG 3.45Å; A231-L235 PolarHBondContact O-N 3.34Å
232	L	96.1	Very high	94.1	Very high	6 Å²	6	20.5 Å²	20.5	3%	0.031	11%	0.105	C	C	.	.	H	α-helix	trans	-61.2	-45.3	175.8	-72.7	174.6	0	0	0	111.5	S178 Y181 M228 I229 A234 L235 V236	S178-L232 WeakPolarHBondContact OG-CD1 3.27Å; Y181-L232 HydrophobicContact CD2-CD2 3.99Å; Y181-L232 HydrophobicContact CG-CD2 3.87Å; M228-L232 WeakPolarHBondContact O-CG 3.34Å; M228-L232 PolarHBondContact O-N 2.96Å; I229-L232 PolarHBondContact O-N 3.23Å; L232-A234 VanDerWaalsContact C-N 3.35Å; L232-A234 PolarHBondContact O-N 3.3Å; L232-L235 PolarHBondContact O-N 3.1Å; L232-V236 VanDerWaalsContact O-CG2 3.31Å; L232-V236 WeakPolarHBondContact O-CG2 3.24Å; L232-V236 PolarHBondContact O-N 3.21Å
233	M	95.1	Very high	94	Very high	43 Å²	43	20.8 Å²	20.8	21%	0.212	11%	0.107	C	C	.	.	H	α-helix	trans	-60.7	-42.9	174.8	-80.8	-61.1	-65.2	0	0	112.2	L173 I229 S230 V236 F237 I329	L173-M233 HydrophobicContact CD1-CG 3.8Å; L173-M233 HydrophobicContact CD1-SD 3.62Å; L173-M233 HydrophobicContact CD2-CG 3.72Å; L173-M233 HydrophobicContact CD2-SD 3.34Å; L173-M233 WeakPolarHBondContact CD2-SD 3.37Å; L173-M233 HydrophobicContact CG-CG 4.42Å; L173-M233 HydrophobicContact CG-SD 4.01Å; I229-M233 WeakPolarHBondContact O-CB 3.43Å; I229-M233 WeakPolarHBondContact O-CG 3.24Å; I229-M233 PolarHBondContact O-N 2.87Å; S230-M233 PolarHBondContact O-N 3.39Å; M233-V236 PolarHBondContact O-N 3.3Å; M233-F237 HydrophobicContact CE-CE2 3.74Å; M233-F237 HydrophobicContact CE-CZ 4.18Å; M233-F237 VanDerWaalsContact O-CD2 3.26Å; M233-F237 WeakPolarHBondContact O-CD2 3.47Å; M233-F237 PolarHBondContact O-N 3.25Å; M233-I329 HydrophobicContact CB-CD1 3.85Å; M233-I329 HydrophobicContact CB-CG1 3.94Å; M233-I329 HydrophobicContact CB-CG2 4.3Å; M233-I329 HydrophobicContact CG-CD1 4.21Å
234	A	96.5	Very high	94.1	Very high	0 Å²	0	25.3 Å²	25.3	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-62.3	-43.2	176.5	0	0	0	0	0	111.6	V96 S230 A231 L232 V236 F237 I238 V333	V96-A234 HydrophobicContact CG2-CB 4.09Å; S230-A234 WeakPolarHBondContact O-CB 3.4Å; S230-A234 PolarHBondContact O-N 2.95Å; A231-A234 PolarHBondContact O-N 2.88Å; L232-A234 VanDerWaalsContact C-N 3.35Å; L232-A234 PolarHBondContact O-N 3.3Å; A234-V236 VanDerWaalsContact C-N 3.34Å; A234-V236 PolarHBondContact O-N 3.39Å; A234-F237 PolarHBondContact O-N 3.17Å; A234-I238 WeakPolarHBondContact O-CG1 3.4Å; A234-I238 PolarHBondContact O-N 3.41Å; A234-V333 HydrophobicContact CB-CG2 3.92Å
235	L	95.5	Very high	94	Very high	2 Å²	2	23.1 Å²	23.1	1%	0.01	11%	0.105	C	C	.	.	H	α-helix	trans	-61.8	-39.4	176	-72.7	168.2	0	0	0	112.5	V96 T99 I100 Y106 Y181 A231 L232 I238 K239	V96-L235 HydrophobicContact CG1-CD2 4.3Å; T99-L235 HydrophobicContact CG2-CD1 3.77Å; T99-L235 HydrophobicContact CG2-CD2 3.73Å; T99-L235 HydrophobicContact CG2-CG 4.42Å; I100-L235 HydrophobicContact CG1-CD2 4.01Å; Y106-L235 HydrophobicContact CD1-CB 3.91Å; Y106-L235 HydrophobicContact CD1-CD2 4.07Å; Y106-L235 HydrophobicContact CD1-CG 4.49Å; Y106-L235 HydrophobicContact CD2-CD2 4.32Å; Y106-L235 HydrophobicContact CE1-CB 3.72Å; Y106-L235 HydrophobicContact CE1-CD1 4.46Å; Y106-L235 HydrophobicContact CE1-CD2 4.44Å; Y106-L235 HydrophobicContact CE1-CG 4.43Å; Y106-L235 HydrophobicContact CE2-CD1 4.48Å; Y106-L235 HydrophobicContact CG-CD2 4.02Å; Y181-L235 HydrophobicContact CD2-CD1 4.03Å; Y181-L235 HydrophobicContact CE2-CD1 3.98Å; A231-L235 VanDerWaalsContact O-CG 3.3Å; A231-L235 WeakPolarHBondContact O-CG 3.45Å; A231-L235 PolarHBondContact O-N 3.34Å; L232-L235 PolarHBondContact O-N 3.1Å; L235-I238 PolarHBondContact O-N 3.34Å; L235-K239 VanDerWaalsContact O-CB 3.3Å; L235-K239 WeakPolarHBondContact O-CB 3.42Å; L235-K239 PolarHBondContact O-N 2.82Å
236	V	93.7	Very high	94	Very high	18 Å²	18	22.3 Å²	22.3	11%	0.109	10%	0.103	C	C	.	.	H	α-helix	trans	-60.8	-46.8	173.8	171.6	0	0	0	0	110.6	F177 L232 M233 A234 K239 Y240	F177-V236 HydrophobicContact CD1-CG2 3.42Å; F177-V236 VanDerWaalsContact CD1-CG2 3.42Å; F177-V236 HydrophobicContact CD2-CG2 4.39Å; F177-V236 HydrophobicContact CE1-CB 4.4Å; F177-V236 HydrophobicContact CE1-CG1 4.15Å; F177-V236 HydrophobicContact CE1-CG2 3.29Å; F177-V236 HydrophobicContact CE2-CG2 4.24Å; F177-V236 HydrophobicContact CG-CG2 4Å; F177-V236 HydrophobicContact CZ-CG1 4.04Å; F177-V236 HydrophobicContact CZ-CG2 3.72Å; L232-V236 VanDerWaalsContact O-CG2 3.31Å; L232-V236 WeakPolarHBondContact O-CG2 3.24Å; L232-V236 PolarHBondContact O-N 3.21Å; M233-V236 PolarHBondContact O-N 3.3Å; A234-V236 VanDerWaalsContact C-N 3.34Å; A234-V236 PolarHBondContact O-N 3.39Å; V236-K239 PolarHBondContact O-N 3.23Å; V236-Y240 HydrophobicContact CG1-CD2 4.04Å; V236-Y240 HydrophobicContact CG1-CE2 4.36Å; V236-Y240 VanDerWaalsContact O-CD2 3.28Å; V236-Y240 WeakPolarHBondContact O-CD2 3.49Å; V236-Y240 PolarHBondContact O-N 3.2Å
237	F	93.7	Very high	94.1	Very high	36 Å²	36	23.3 Å²	23.3	16%	0.158	11%	0.106	C	C	.	.	H	α-helix	trans	-61.7	-45.5	176	-80.3	-53.9	0	0	0	111.9	M139 M233 A234 K239 L241 I329 V333	M139-F237 HydrophobicContact CE-CD1 3.88Å; M139-F237 HydrophobicContact CE-CE1 3.34Å; M139-F237 HydrophobicContact CE-CZ 4.21Å; M233-F237 HydrophobicContact CE-CE2 3.74Å; M233-F237 HydrophobicContact CE-CZ 4.18Å; M233-F237 VanDerWaalsContact O-CD2 3.26Å; M233-F237 WeakPolarHBondContact O-CD2 3.47Å; M233-F237 PolarHBondContact O-N 3.25Å; A234-F237 PolarHBondContact O-N 3.17Å; F237-K239 PolarHBondContact O-N 2.97Å; F237-L241 HydrophobicContact CB-CD1 3.83Å; F237-L241 HydrophobicContact CD1-CD1 3.63Å; F237-L241 HydrophobicContact CD1-CG 4.43Å; F237-L241 HydrophobicContact CG-CD1 4.13Å; F237-L241 WeakPolarHBondContact O-CB 3.05Å; F237-L241 WeakPolarHBondContact O-CD1 3.46Å; F237-L241 VanDerWaalsContact O-CG 3.28Å; F237-L241 WeakPolarHBondContact O-CG 3.49Å; F237-L241 PolarHBondContact O-N 2.85Å; F237-I329 HydrophobicContact CD2-CG2 3.73Å; F237-I329 HydrophobicContact CE2-CG2 3.89Å; F237-V333 HydrophobicContact CB-CG2 3.71Å; F237-V333 HydrophobicContact CD2-CG2 4.35Å; F237-V333 HydrophobicContact CG-CG2 4.42Å
238	I	93.7	Very high	94.1	Very high	8 Å²	8	25.3 Å²	25.3	4%	0.041	12%	0.117	C	C	.	.	H	α-helix	trans	-62.7	-41.8	-179.5	-67.9	166	0	0	0	111.9	V96 I100 A234 L235 V333 K337	V96-I238 HydrophobicContact CG1-CD1 3.73Å; I100-I238 HydrophobicContact CD1-CD1 3.59Å; I100-I238 HydrophobicContact CD1-CG2 4.18Å; A234-I238 WeakPolarHBondContact O-CG1 3.4Å; A234-I238 PolarHBondContact O-N 3.41Å; L235-I238 PolarHBondContact O-N 3.34Å; I238-V333 HydrophobicContact CG1-CG1 4.38Å; I238-V333 HydrophobicContact CG1-CG2 4.41Å; I238-K337 HydrophobicContact CB-CD 4.45Å; I238-K337 HydrophobicContact CG1-CD 4.24Å; I238-K337 HydrophobicContact CG1-CG 4.32Å; I238-K337 HydrophobicContact CG2-CD 4.16Å
239	K	92.5	Very high	94.1	Very high	12 Å²	12	23 Å²	23	5%	0.052	11%	0.105	C	C	.	.	H	α-helix	trans	-66.8	-40.8	-176.9	174.1	65	-169.8	73.6	0	113.6	F105 Y106 R108 D110 L235 V236 F237	F105-K239 HydrophobicContact CD1-CD 4.41Å; F105-K239 HydrophobicContact CE1-CD 4.21Å; F105-K239 VanDerWaalsContact O-CD 3.27Å; F105-K239 WeakPolarHBondContact O-CD 3.25Å; F105-K239 WeakPolarHBondContact O-CE 3.25Å; Y106-K239 HydrophobicContact CD1-CB 4.08Å; R108-K239 WeakPolarHBondContact O-CE 3.29Å; R108-K239 PolarHBondContact O-NZ 3.02Å; D110-K239 PolarHBondContact O-NZ 3.42Å; L235-K239 VanDerWaalsContact O-CB 3.3Å; L235-K239 WeakPolarHBondContact O-CB 3.42Å; L235-K239 PolarHBondContact O-N 2.82Å; V236-K239 PolarHBondContact O-N 3.23Å; F237-K239 PolarHBondContact O-N 2.97Å
240	Y	91.4	Very high	94.1	Very high	66 Å²	66	22.4 Å²	22.4	26%	0.259	10%	0.103	S	C	.	.	H	α-helix	trans	-108.4	-5.2	-168.2	-62.1	-69.4	0	0	0	114.2	L113 V236	L113-Y240 VanDerWaalsContact CG-CB 3.49Å; L113-Y240 HydrophobicContact CG-CG 4.36Å; L113-Y240 PolarHBondContact N-O 3.07Å; V236-Y240 HydrophobicContact CG1-CD2 4.04Å; V236-Y240 HydrophobicContact CG1-CE2 4.36Å; V236-Y240 VanDerWaalsContact O-CD2 3.28Å; V236-Y240 WeakPolarHBondContact O-CD2 3.49Å; V236-Y240 PolarHBondContact O-N 3.2Å
241	L	90.2	Very high	94.1	Very high	11 Å²	11	24 Å²	24	6%	0.058	12%	0.116	C	C	.	.	S	Bend	trans	-94.4	126.4	174.8	-74	164.8	0	0	0	112.2	L113 T116 M139 F237 T245 A246 I249 K337	L113-L241 HydrophobicContact CD1-CD2 4.09Å; L113-L241 HydrophobicContact CD1-CG 3.9Å; T116-L241 HydrophobicContact CG2-CD2 4.13Å; M139-L241 HydrophobicContact CE-CD1 4.38Å; M139-L241 HydrophobicContact CE-CD2 4.38Å; M139-L241 HydrophobicContact SD-CD2 3.74Å; F237-L241 HydrophobicContact CB-CD1 3.83Å; F237-L241 HydrophobicContact CD1-CD1 3.63Å; F237-L241 HydrophobicContact CD1-CG 4.43Å; F237-L241 HydrophobicContact CG-CD1 4.13Å; F237-L241 WeakPolarHBondContact O-CB 3.05Å; F237-L241 WeakPolarHBondContact O-CD1 3.46Å; F237-L241 VanDerWaalsContact O-CG 3.28Å; F237-L241 WeakPolarHBondContact O-CG 3.49Å; F237-L241 PolarHBondContact O-N 2.85Å; L241-T245 HydrophobicContact CD2-CG2 4.27Å; L241-A246 HydrophobicContact CB-CB 4.09Å; L241-I249 HydrophobicContact CD1-CD1 4.48Å; L241-I249 HydrophobicContact CD2-CD1 3.58Å; L241-K337 PolarHBondContact O-NZ 3.25Å
242	P	90.8	Very high	94	Very high	16 Å²	16	27 Å²	27	10%	0.104	13%	0.134	C	C	.	.			trans	-56.4	158.2	166.5	-23.1	34.2	0	0	0	112.4	Q112 E120 A246	Q112-P242 HydrophobicContact CG-CG 4.41Å; E120-P242 HydrophobicContact CG-CB 3.76Å; E120-P242 HydrophobicContact CG-CG 4.41Å; E120-P242 VanDerWaalsContact OE1-CB 3.31Å; E120-P242 WeakPolarHBondContact OE1-CB 3.31Å; P242-A246 VanDerWaalsContact O-CB 3.23Å; P242-A246 WeakPolarHBondContact O-CB 3.24Å; P242-A246 PolarHBondContact O-N 3.04Å
243	E	90.8	Very high	93.9	Very high	51 Å²	51	27.2 Å²	27.2	24%	0.238	14%	0.135	C	C	.	.	H	α-helix	trans	-65.4	-55	-171.7	-72.3	159.4	-145.1	0	0	113.1	K109 R128 A246 W247 T341	K109-E243 WeakPolarHBondContact CE-OE1 3.32Å; K109-E243 IonicContact NZ-OE1 3.51Å; K109-E243 PolarHBondContact NZ-OE1 3.26Å; R128-E243 IonicContact NH2-OE2 3.92Å; E243-A246 PolarHBondContact O-N 3.21Å; E243-W247 PolarHBondContact O-N 2.96Å; E243-T341 HydrophobicContact CG-CG2 4.06Å
244	W	93.1	Very high	93.9	Very high	107 Å²	107	25.5 Å²	25.5	41%	0.405	13%	0.127	S	C	.	.	H	α-helix	trans	-68.4	-41.6	-176.4	-74.4	38.8	0	0	0	110.4	E120 R128 A129 S132 A246 W247 L248	E120-W244 WeakPolarHBondContact OE1-CB 3.01Å; E120-W244 PolarHBondContact OE2-N 3.3Å; R128-W244 VanDerWaalsContact NH2-CD1 3.26Å; A129-W244 HydrophobicContact CB-CZ3 4.17Å; S132-W244 VanDerWaalsContact OG-CB 3.3Å; S132-W244 WeakPolarHBondContact OG-CB 3.5Å; W244-A246 VanDerWaalsContact C-N 3.32Å; W244-A246 PolarHBondContact O-N 3.48Å; W244-W247 PolarHBondContact O-N 3.44Å; W244-L248 WeakPolarHBondContact O-CG 3.43Å; W244-L248 PolarHBondContact O-N 3.31Å
245	T	94	Very high	93.7	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-54.7	-45.4	172.7	-59.3	0	0	0	0	111.6	T116 E120 S132 N135 L241 L248 I249	T116-T245 HydrophobicContact CG2-CG2 4.13Å; E120-T245 WeakPolarHBondContact OE1-CB 3.38Å; E120-T245 PolarHBondContact OE1-N 2.91Å; E120-T245 PolarHBondContact OE1-OG1 3.25Å; S132-T245 WeakPolarHBondContact CA-OG1 2.92Å; N135-T245 HydrophobicContact CB-CG2 3.6Å; L241-T245 HydrophobicContact CD2-CG2 4.27Å; T245-L248 PolarHBondContact O-N 3.03Å; T245-I249 HydrophobicContact CG2-CD1 3.66Å; T245-I249 HydrophobicContact CG2-CG1 4.42Å; T245-I249 WeakPolarHBondContact O-CB 3.46Å; T245-I249 WeakPolarHBondContact O-CD1 3.39Å; T245-I249 VanDerWaalsContact O-CG1 3.24Å; T245-I249 WeakPolarHBondContact O-CG1 3.25Å; T245-I249 PolarHBondContact O-N 2.83Å
246	A	93.9	Very high	93.7	Very high	2 Å²	2	31.9 Å²	31.9	2%	0.017	16%	0.161	C	C	.	.	H	α-helix	trans	-63	-45.2	178.9	0	0	0	0	0	112.5	L241 P242 E243 W244 I249 L250 K337	L241-A246 HydrophobicContact CB-CB 4.09Å; P242-A246 VanDerWaalsContact O-CB 3.23Å; P242-A246 WeakPolarHBondContact O-CB 3.24Å; P242-A246 PolarHBondContact O-N 3.04Å; E243-A246 PolarHBondContact O-N 3.21Å; W244-A246 VanDerWaalsContact C-N 3.32Å; W244-A246 PolarHBondContact O-N 3.48Å; A246-I249 PolarHBondContact O-N 3.05Å; A246-L250 WeakPolarHBondContact O-CG 3.35Å; A246-L250 PolarHBondContact O-N 3.34Å; A246-K337 HydrophobicContact CB-CD 4.36Å
247	W	95.4	Very high	93.6	Very high	24 Å²	24	32.1 Å²	32.1	9%	0.091	16%	0.162	C	C	.	.	H	α-helix	trans	-62.8	-42.4	176.9	-66.6	121.9	0	0	0	112.1	E243 W244 L250 A251 L334 K337 L385 Y388 F389	E243-W247 PolarHBondContact O-N 2.96Å; W244-W247 PolarHBondContact O-N 3.44Å; W247-L250 HydrophobicContact CE3-CD1 4.03Å; W247-L250 HydrophobicContact CZ3-CD1 4.15Å; W247-L250 PolarHBondContact O-N 3.39Å; W247-A251 PolarHBondContact O-N 3.29Å; W247-L334 HydrophobicContact CZ3-CG 4.16Å; W247-K337 HydrophobicContact CH2-CB 4.18Å; W247-K337 HydrophobicContact CZ2-CB 3.97Å; W247-L385 HydrophobicContact CD2-CD2 4.48Å; W247-L385 HydrophobicContact CE3-CD2 3.36Å; W247-L385 HydrophobicContact CZ3-CD2 3.69Å; W247-Y388 HydrophobicContact CD2-CE1 4.33Å; W247-Y388 AromaticContact CE2-CE1 3.52Å; W247-Y388 AromaticContact CE2-CZ 3.84Å; W247-Y388 AromaticContact CH2-CD1 3.59Å; W247-Y388 HydrophobicContact CH2-CD1 3.59Å; W247-Y388 AromaticContact CH2-CD2 3.63Å; W247-Y388 HydrophobicContact CH2-CD2 3.63Å; W247-Y388 AromaticContact CH2-CE1 3.71Å; W247-Y388 HydrophobicContact CH2-CE1 3.71Å; W247-Y388 AromaticContact CH2-CE2 3.79Å; W247-Y388 HydrophobicContact CH2-CE2 3.79Å; W247-Y388 AromaticContact CH2-CG 3.55Å; W247-Y388 HydrophobicContact CH2-CG 3.55Å; W247-Y388 AromaticContact CH2-CZ 3.82Å; W247-Y388 AromaticContact CZ2-CD1 3.63Å; W247-Y388 HydrophobicContact CZ2-CD1 3.63Å; W247-Y388 AromaticContact CZ2-CD2 3.9Å; W247-Y388 HydrophobicContact CZ2-CD2 3.9Å; W247-Y388 AromaticContact CZ2-CE1 3.21Å; W247-Y388 HydrophobicContact CZ2-CE1 3.21Å; W247-Y388 AromaticContact CZ2-CE2 3.55Å; W247-Y388 HydrophobicContact CZ2-CE2 3.55Å; W247-Y388 AromaticContact CZ2-CG 3.95Å; W247-Y388 HydrophobicContact CZ2-CG 3.95Å; W247-Y388 AromaticContact CZ2-CZ 3.18Å; W247-Y388 HydrophobicContact CZ3-CD1 4.05Å; W247-Y388 HydrophobicContact CZ3-CE1 4.44Å; W247-Y388 HydrophobicContact CZ3-CG 4.14Å; W247-Y388 AromaticContact NE1-CE1 3.9Å; W247-F389 HydrophobicContact CD2-CZ 4.4Å; W247-F389 HydrophobicContact CG-CZ 4.29Å
248	L	95.6	Very high	93.5	Very high	60 Å²	60	33.8 Å²	33.8	31%	0.314	17%	0.172	S	C	.	.	H	α-helix	trans	-63.3	-42.3	174.9	-71.6	178.7	0	0	0	111.9	I133 A136 W244 T245 A251 V252	I133-L248 HydrophobicContact CG1-CD1 3.86Å; A136-L248 HydrophobicContact CB-CB 3.99Å; W244-L248 WeakPolarHBondContact O-CG 3.43Å; W244-L248 PolarHBondContact O-N 3.31Å; T245-L248 PolarHBondContact O-N 3.03Å; L248-A251 PolarHBondContact O-N 3.4Å; L248-V252 WeakPolarHBondContact O-CB 3.31Å; L248-V252 VanDerWaalsContact O-CG2 3.25Å; L248-V252 WeakPolarHBondContact O-CG2 3.25Å; L248-V252 PolarHBondContact O-N 3.44Å
249	I	95.1	Very high	93.5	Very high	4 Å²	4	37 Å²	37	2%	0.021	19%	0.191	C	C	.	.	H	α-helix	trans	-62.2	-45.1	176.8	-72.6	160.4	0	0	0	110.9	A136 M139 I140 L241 T245 A246 A251 V252 I253	A136-I249 HydrophobicContact CB-CG1 4Å; M139-I249 HydrophobicContact CB-CD1 4.33Å; M139-I249 HydrophobicContact CE-CD1 4.04Å; M139-I249 HydrophobicContact CE-CG2 4.28Å; M139-I249 HydrophobicContact CG-CD1 4.2Å; M139-I249 HydrophobicContact SD-CD1 3.4Å; M139-I249 WeakPolarHBondContact SD-CD1 3.29Å; M139-I249 HydrophobicContact SD-CG1 4.42Å; I140-I249 HydrophobicContact CD1-CG2 4.48Å; L241-I249 HydrophobicContact CD1-CD1 4.48Å; L241-I249 HydrophobicContact CD2-CD1 3.58Å; T245-I249 HydrophobicContact CG2-CD1 3.66Å; T245-I249 HydrophobicContact CG2-CG1 4.42Å; T245-I249 WeakPolarHBondContact O-CB 3.46Å; T245-I249 WeakPolarHBondContact O-CD1 3.39Å; T245-I249 VanDerWaalsContact O-CG1 3.24Å; T245-I249 WeakPolarHBondContact O-CG1 3.25Å; T245-I249 PolarHBondContact O-N 2.83Å; A246-I249 PolarHBondContact O-N 3.05Å; I249-A251 VanDerWaalsContact C-N 3.33Å; I249-A251 PolarHBondContact O-N 2.71Å; I249-V252 PolarHBondContact O-N 3.11Å; I249-I253 VanDerWaalsContact O-CB 3.26Å; I249-I253 WeakPolarHBondContact O-CB 3.45Å; I249-I253 VanDerWaalsContact O-CG2 3.31Å; I249-I253 WeakPolarHBondContact O-CG2 3.33Å; I249-I253 PolarHBondContact O-N 3.01Å
250	L	95.4	Very high	93.4	Very high	2 Å²	2	36.5 Å²	36.5	1%	0.01	19%	0.19	C	C	.	.	H	α-helix	trans	-60.1	-43.8	177	-71.7	174.4	0	0	0	111.5	A246 W247 S254 F330 V333 L334 I381	A246-L250 WeakPolarHBondContact O-CG 3.35Å; A246-L250 PolarHBondContact O-N 3.34Å; W247-L250 HydrophobicContact CE3-CD1 4.03Å; W247-L250 HydrophobicContact CZ3-CD1 4.15Å; W247-L250 PolarHBondContact O-N 3.39Å; L250-S254 WeakPolarHBondContact O-CB 3.46Å; L250-S254 PolarHBondContact O-N 3.45Å; L250-F330 HydrophobicContact CD2-CB 4.11Å; L250-F330 HydrophobicContact CD2-CD1 3.78Å; L250-F330 HydrophobicContact CD2-CG 4.37Å; L250-V333 HydrophobicContact CD1-CG1 4.38Å; L250-V333 HydrophobicContact CD2-CG1 4.27Å; L250-L334 HydrophobicContact CD1-CB 4.02Å; L250-L334 HydrophobicContact CD1-CG 4.27Å; L250-I381 HydrophobicContact CB-CG2 4.35Å; L250-I381 HydrophobicContact CD2-CD1 4.47Å
251	A	95.6	Very high	93.3	Very high	35 Å²	35	34.5 Å²	34.5	29%	0.289	19%	0.185	S	C	.	.	H	α-helix	trans	-64.2	-50.7	176.4	0	0	0	0	0	111.8	W247 L248 I249 I253 S254 V255 L385	W247-A251 PolarHBondContact O-N 3.29Å; L248-A251 PolarHBondContact O-N 3.4Å; I249-A251 VanDerWaalsContact C-N 3.33Å; I249-A251 PolarHBondContact O-N 2.71Å; A251-I253 PolarHBondContact O-N 2.73Å; A251-S254 PolarHBondContact O-N 3.02Å; A251-S254 PolarHBondContact O-OG 3.34Å; A251-V255 PolarHBondContact O-N 2.88Å; A251-L385 HydrophobicContact CB-CD1 4.07Å
252	V	95.7	Very high	93.3	Very high	65 Å²	65	38.2 Å²	38.2	39%	0.394	20%	0.204	S	C	.	.	H	α-helix	trans	-67.3	-39	-176.7	175.7	0	0	0	0	111.8	I140 L248 I249 S254 V255 Y256	I140-V252 HydrophobicContact CD1-CB 4.34Å; I140-V252 HydrophobicContact CD1-CG1 4Å; I140-V252 HydrophobicContact CG1-CB 4.32Å; I140-V252 HydrophobicContact CG1-CG1 3.81Å; I140-V252 HydrophobicContact CG2-CG1 4.16Å; L248-V252 WeakPolarHBondContact O-CB 3.31Å; L248-V252 VanDerWaalsContact O-CG2 3.25Å; L248-V252 WeakPolarHBondContact O-CG2 3.25Å; L248-V252 PolarHBondContact O-N 3.44Å; I249-V252 PolarHBondContact O-N 3.11Å; V252-S254 VanDerWaalsContact C-N 3.3Å; V252-S254 PolarHBondContact O-N 3.42Å; V252-V255 PolarHBondContact O-N 3.49Å; V252-Y256 WeakPolarHBondContact O-CB 3.47Å; V252-Y256 PolarHBondContact O-N 2.85Å
253	I	94.2	Very high	93.3	Very high	10 Å²	10	40 Å²	40	5%	0.051	22%	0.216	C	C	.	.	H	α-helix	trans	-69.1	-32.9	179.5	-151.6	173.9	0	0	0	111.8	I140 I143 I249 A251 V255 Y256 D257 F330	I140-I253 HydrophobicContact CD1-CB 4.14Å; I140-I253 HydrophobicContact CD1-CG1 4.39Å; I143-I253 HydrophobicContact CD1-CD1 4.33Å; I249-I253 VanDerWaalsContact O-CB 3.26Å; I249-I253 WeakPolarHBondContact O-CB 3.45Å; I249-I253 VanDerWaalsContact O-CG2 3.31Å; I249-I253 WeakPolarHBondContact O-CG2 3.33Å; I249-I253 PolarHBondContact O-N 3.01Å; A251-I253 PolarHBondContact O-N 2.73Å; I253-V255 VanDerWaalsContact C-N 3.31Å; I253-V255 PolarHBondContact O-N 3.36Å; I253-Y256 PolarHBondContact O-N 3.25Å; I253-D257 WeakPolarHBondContact O-CB 3.45Å; I253-D257 PolarHBondContact O-N 3.3Å; I253-F330 HydrophobicContact CD1-CD2 4.34Å; I253-F330 HydrophobicContact CD1-CE1 3.81Å; I253-F330 HydrophobicContact CD1-CE2 3.49Å; I253-F330 VanDerWaalsContact CD1-CE2 3.49Å; I253-F330 HydrophobicContact CD1-CZ 3.19Å; I253-F330 HydrophobicContact CG2-CD1 4.35Å; I253-F330 HydrophobicContact CG2-CE1 4.37Å
254	S	94.1	Very high	93.2	Very high	7 Å²	7	42.3 Å²	42.3	5%	0.049	24%	0.235	C	C	.	.	H	α-helix	trans	-62.7	-39.5	174.5	81	0	0	0	0	111.8	L250 A251 V252 L258	L250-S254 WeakPolarHBondContact O-CB 3.46Å; L250-S254 PolarHBondContact O-N 3.45Å; A251-S254 PolarHBondContact O-N 3.02Å; A251-S254 PolarHBondContact O-OG 3.34Å; V252-S254 VanDerWaalsContact C-N 3.3Å; V252-S254 PolarHBondContact O-N 3.42Å; S254-L258 PolarHBondContact O-N 3.34Å
255	V	94.2	Very high	93	Very high	88 Å²	88	46.4 Å²	46.4	53%	0.533	26%	0.256	S	S	.	.	H	α-helix	trans	-70.5	-42.8	173.8	178.2	0	0	0	0	111	A251 V252 I253 L258 V259	A251-V255 PolarHBondContact O-N 2.88Å; V252-V255 PolarHBondContact O-N 3.49Å; I253-V255 VanDerWaalsContact C-N 3.31Å; I253-V255 PolarHBondContact O-N 3.36Å; V255-L258 WeakPolarHBondContact O-CB 3.31Å; V255-L258 PolarHBondContact O-N 3.05Å; V255-V259 WeakPolarHBondContact O-CG2 3.29Å; V255-V259 PolarHBondContact O-N 2.96Å
256	Y	93.9	Very high	92.7	Very high	47 Å²	47	46.5 Å²	46.5	18%	0.184	26%	0.258	C	S	.	.	H	α-helix	trans	-61.9	-44.7	178.2	173.5	-103.8	0	0	0	112.1	V144 V252 I253 L258 V259 A260	V144-Y256 HydrophobicContact CG1-CE2 4.34Å; V144-Y256 HydrophobicContact CG2-CD2 4.02Å; V144-Y256 HydrophobicContact CG2-CE1 4.35Å; V144-Y256 HydrophobicContact CG2-CE2 3.56Å; V252-Y256 WeakPolarHBondContact O-CB 3.47Å; V252-Y256 PolarHBondContact O-N 2.85Å; I253-Y256 PolarHBondContact O-N 3.25Å; Y256-L258 VanDerWaalsContact C-N 3.33Å; Y256-L258 PolarHBondContact O-N 3.34Å; Y256-V259 PolarHBondContact O-N 3.5Å; Y256-A260 HydrophobicContact CE1-CB 4.24Å; Y256-A260 HydrophobicContact CE2-CB 4.3Å; Y256-A260 WeakPolarHBondContact O-CB 3.42Å; Y256-A260 PolarHBondContact O-N 3.47Å
257	D	92.3	Very high	92.4	Very high	24 Å²	24	47.6 Å²	47.6	13%	0.128	26%	0.264	C	S	.	.	H	α-helix	trans	-60.9	-42.3	177.6	-171.1	50.1	0	0	0	111.3	I253 V259 A260 V261 P375 L377	I253-D257 WeakPolarHBondContact O-CB 3.45Å; I253-D257 PolarHBondContact O-N 3.3Å; D257-V259 PolarHBondContact O-N 3.31Å; D257-A260 PolarHBondContact O-N 3.43Å; D257-V261 WeakPolarHBondContact O-CB 3.48Å; D257-V261 WeakPolarHBondContact O-CG2 3.17Å; D257-V261 PolarHBondContact O-N 2.95Å; D257-P375 WeakPolarHBondContact OD2-CB 3.43Å; D257-L377 HydrophobicContact CB-CD1 4.16Å
258	L	91.3	Very high	91.8	Very high	71 Å²	71	49 Å²	49	37%	0.372	27%	0.274	S	S	.	.	H	α-helix	trans	-55.8	-50.4	173.3	-171.1	94.1	0	0	0	112	S254 V255 Y256 L262 P375 P378	S254-L258 PolarHBondContact O-N 3.34Å; V255-L258 WeakPolarHBondContact O-CB 3.31Å; V255-L258 PolarHBondContact O-N 3.05Å; Y256-L258 VanDerWaalsContact C-N 3.33Å; Y256-L258 PolarHBondContact O-N 3.34Å; L258-L262 HydrophobicContact CD1-CD1 3.95Å; L258-L262 HydrophobicContact CG-CD1 3.89Å; L258-L262 WeakPolarHBondContact O-CB 3.4Å; L258-L262 WeakPolarHBondContact O-CG 3.33Å; L258-L262 PolarHBondContact O-N 3.4Å; L258-L262 VanDerWaalsContact O-N 3.07Å; L258-P375 HydrophobicContact CD1-CG 4.08Å; L258-P378 HydrophobicContact CB-CB 4.48Å; L258-P378 HydrophobicContact CB-CG 4.33Å; L258-P378 HydrophobicContact CD1-CB 4.15Å; L258-P378 HydrophobicContact CD1-CG 3.79Å
259	V	92.9	Very high	91.4	Very high	74 Å²	74	50.4 Å²	50.4	45%	0.448	28%	0.275	S	S	.	.	H	α-helix	trans	-68.8	-42	-178.4	174.5	0	0	0	0	111.3	V255 Y256 D257 V261 C263	V255-V259 WeakPolarHBondContact O-CG2 3.29Å; V255-V259 PolarHBondContact O-N 2.96Å; Y256-V259 PolarHBondContact O-N 3.5Å; D257-V259 PolarHBondContact O-N 3.31Å; V259-V261 VanDerWaalsContact C-N 3.3Å; V259-V261 PolarHBondContact O-N 3.03Å; V259-C263 WeakPolarHBondContact O-CB 3.38Å; V259-C263 PolarHBondContact O-N 3.44Å; V259-C263 VanDerWaalsContact O-N 3.09Å; V259-C263 PolarHBondContact O-SG 3.46Å
260	A	91.4	Very high	90.9	Very high	3 Å²	3	53 Å²	53	3%	0.025	29%	0.288	C	S	.	.	H	α-helix	trans	-70.6	-22.8	-176.4	0	0	0	0	0	113.7	Y256 D257 G266 P267 L268 R269	Y256-A260 HydrophobicContact CE1-CB 4.24Å; Y256-A260 HydrophobicContact CE2-CB 4.3Å; Y256-A260 WeakPolarHBondContact O-CB 3.42Å; Y256-A260 PolarHBondContact O-N 3.47Å; D257-A260 PolarHBondContact O-N 3.43Å; A260-G266 CarbonylContact O-C 3.5Å; A260-G266 WeakPolarHBondContact O-CA 3.47Å; A260-P267 HydrophobicContact CB-CG 4.21Å; A260-L268 HydrophobicContact CB-CD1 4.1Å; A260-L268 HydrophobicContact CB-CG 4.46Å; A260-R269 PolarHBondContact O-N 3.21Å
261	V	89.2	Confident	90.4	Very high	24 Å²	24	54 Å²	54	15%	0.145	29%	0.292	C	S	.	.	H	α-helix	trans	-94.7	-43.6	176.3	177.6	0	0	0	0	112	D257 V259 L268 P375	D257-V261 WeakPolarHBondContact O-CB 3.48Å; D257-V261 WeakPolarHBondContact O-CG2 3.17Å; D257-V261 PolarHBondContact O-N 2.95Å; V259-V261 VanDerWaalsContact C-N 3.3Å; V259-V261 PolarHBondContact O-N 3.03Å; V261-L268 HydrophobicContact CG2-CB 4.25Å; V261-L268 HydrophobicContact CG2-CD1 4.12Å; V261-P375 HydrophobicContact CB-CB 4.33Å; V261-P375 HydrophobicContact CB-CG 4.49Å; V261-P375 HydrophobicContact CG2-CB 4.26Å
262	L	90.1	Very high	89.8	Confident	89 Å²	89	54.5 Å²	54.5	47%	0.466	29%	0.292	S	S	.	.	H	α-helix	trans	-78.8	-33.4	-175	-65.9	176.3	0	0	0	113.4	L258 R269 L374	L258-L262 HydrophobicContact CD1-CD1 3.95Å; L258-L262 HydrophobicContact CG-CD1 3.89Å; L258-L262 WeakPolarHBondContact O-CB 3.4Å; L258-L262 WeakPolarHBondContact O-CG 3.33Å; L258-L262 PolarHBondContact O-N 3.4Å; L258-L262 VanDerWaalsContact O-N 3.07Å; L262-R269 PolarHBondContact O-NH1 3.36Å; L262-L374 HydrophobicContact CD2-CD2 4.46Å
263	C	90.5	Very high	89.5	Confident	53 Å²	53	54.8 Å²	54.8	36%	0.358	29%	0.289	S	S	.	.	S	Bend	trans	-70.4	138.2	-177.8	-66.5	0	0	0	0	111.6	V259 K265 G266 R269	V259-C263 WeakPolarHBondContact O-CB 3.38Å; V259-C263 PolarHBondContact O-N 3.44Å; V259-C263 VanDerWaalsContact O-N 3.09Å; V259-C263 PolarHBondContact O-SG 3.46Å; C263-K265 PolarHBondContact O-N 2.95Å; C263-K265 VanDerWaalsContact O-N 3.14Å; C263-G266 PolarHBondContact O-N 2.96Å; C263-R269 VanDerWaalsContact O-CD 3.31Å; C263-R269 WeakPolarHBondContact O-CD 3.45Å
264	P	89	Confident	89.1	Confident	99 Å²	99	55.1 Å²	55.1	64%	0.643	29%	0.292	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.4	-27	178.1	-25	33.6	0	0	0	114.4	G266	P264-G266 VanDerWaalsContact C-N 3.35Å
265	K	88.4	Confident	88.5	Confident	193 Å²	193	55 Å²	55	84%	0.839	29%	0.291	S	S	*	.	T	Hydrogen-bonded Turn	trans	-97.2	16.3	176.1	-62.4	-168.6	175.1	78.7	0	112.9	C263	C263-K265 PolarHBondContact O-N 2.95Å; C263-K265 VanDerWaalsContact O-N 3.14Å
266	G	87.6	Confident	87.9	Confident	3 Å²	3	57 Å²	57	3%	0.031	30%	0.295	C	S	.	.			trans	-67.3	134.7	-179.7	0	0	0	0	0	111.8	A260 C263 P264 L268 R269 M270	A260-G266 CarbonylContact O-C 3.5Å; A260-G266 WeakPolarHBondContact O-CA 3.47Å; C263-G266 PolarHBondContact O-N 2.96Å; P264-G266 VanDerWaalsContact C-N 3.35Å; G266-L268 PolarHBondContact O-N 3.32Å; G266-R269 PolarHBondContact O-N 3.38Å; G266-M270 PolarHBondContact O-N 3.08Å
267	P	88.1	Confident	87.7	Confident	24 Å²	24	62.2 Å²	62.2	16%	0.156	32%	0.32	C	S	.	.	H	α-helix	trans	-62.5	-42.6	-177.5	22.9	-31.5	0	0	0	111.8	T147 V151 A260 M270 L271	T147-P267 HydrophobicContact CG2-CB 4.17Å; T147-P267 HydrophobicContact CG2-CG 4.23Å; V151-P267 HydrophobicContact CG2-CB 3.9Å; V151-P267 VanDerWaalsContact CG2-O 3.24Å; V151-P267 WeakPolarHBondContact CG2-O 3.41Å; A260-P267 HydrophobicContact CB-CG 4.21Å; P267-M270 PolarHBondContact O-N 3.49Å; P267-L271 PolarHBondContact O-N 3.37Å; P267-L271 VanDerWaalsContact O-N 3.12Å
268	L	82.9	Confident	87.4	Confident	55 Å²	55	64.1 Å²	64.1	29%	0.288	33%	0.326	S	S	.	.	H	α-helix	trans	-68.2	-41.4	178.6	-68.2	172.3	0	0	0	111.5	T147 A260 V261 G266 M270 L271 V272	T147-L268 HydrophobicContact CG2-CD2 4.23Å; T147-L268 HydrophobicContact CG2-CG 4.46Å; A260-L268 HydrophobicContact CB-CD1 4.1Å; A260-L268 HydrophobicContact CB-CG 4.46Å; V261-L268 HydrophobicContact CG2-CB 4.25Å; V261-L268 HydrophobicContact CG2-CD1 4.12Å; G266-L268 PolarHBondContact O-N 3.32Å; L268-M270 PolarHBondContact O-N 2.98Å; L268-L271 WeakPolarHBondContact O-CB 3.5Å; L268-L271 PolarHBondContact O-N 3.44Å; L268-V272 WeakPolarHBondContact O-CG2 3.43Å; L268-V272 PolarHBondContact O-N 2.99Å
269	R	86.7	Confident	86.7	Confident	89 Å²	89	68.1 Å²	68.1	34%	0.336	35%	0.347	S	S	.	.	H	α-helix	trans	-59.1	-45.8	174.7	-175.8	176	174.2	162.5	-1	112	A260 L262 C263 G266 L271 V272 E273	A260-R269 PolarHBondContact O-N 3.21Å; L262-R269 PolarHBondContact O-NH1 3.36Å; C263-R269 VanDerWaalsContact O-CD 3.31Å; C263-R269 WeakPolarHBondContact O-CD 3.45Å; G266-R269 PolarHBondContact O-N 3.38Å; R269-L271 VanDerWaalsContact C-N 3.27Å; R269-L271 PolarHBondContact O-N 3.19Å; R269-V272 PolarHBondContact O-N 3.48Å; R269-E273 HydrophobicContact CG-CG 4.36Å; R269-E273 IonicContact CZ-OE1 3.53Å; R269-E273 IonicContact NE-OE1 2.79Å; R269-E273 PolarHBondContact NE-OE1 2.93Å; R269-E273 IonicContact NH2-OE1 3.34Å; R269-E273 PolarHBondContact NH2-OE1 3.37Å; R269-E273 WeakPolarHBondContact O-CG 3.31Å; R269-E273 PolarHBondContact O-N 3.15Å
270	M	85.4	Confident	85.9	Confident	59 Å²	59	68.3 Å²	68.3	29%	0.291	34%	0.343	S	S	.	.	H	α-helix	trans	-60.3	-38.5	177	-174.2	179.1	-56.9	0	0	112	V151 K155 G266 P267 L268 T274	V151-M270 HydrophobicContact CG1-CB 4.36Å; V151-M270 HydrophobicContact CG1-CG 4.31Å; V151-M270 HydrophobicContact CG1-SD 3.95Å; K155-M270 HydrophobicContact CD-SD 4.17Å; G266-M270 PolarHBondContact O-N 3.08Å; P267-M270 PolarHBondContact O-N 3.49Å; L268-M270 PolarHBondContact O-N 2.98Å; M270-T274 VanDerWaalsContact O-CB 3.3Å; M270-T274 WeakPolarHBondContact O-CB 3.43Å; M270-T274 PolarHBondContact O-N 3.34Å; M270-T274 PolarHBondContact O-OG1 2.93Å
271	L	85.5	Confident	85	Confident	22 Å²	22	73.8 Å²	73.8	12%	0.115	38%	0.377	C	S	.	.	H	α-helix	trans	-64	-46.6	177.1	-163.5	161.8	0	0	0	111	L150 V151 Y154 P267 L268 R269 T274 A275 L282	L150-L271 HydrophobicContact CD2-CD1 3.5Å; L150-L271 VanDerWaalsContact CD2-CD1 3.5Å; V151-L271 HydrophobicContact CG2-CB 4.27Å; V151-L271 HydrophobicContact CG2-CD1 4.1Å; Y154-L271 HydrophobicContact CD1-CG 4.31Å; P267-L271 PolarHBondContact O-N 3.37Å; P267-L271 VanDerWaalsContact O-N 3.12Å; L268-L271 WeakPolarHBondContact O-CB 3.5Å; L268-L271 PolarHBondContact O-N 3.44Å; R269-L271 VanDerWaalsContact C-N 3.27Å; R269-L271 PolarHBondContact O-N 3.19Å; L271-T274 PolarHBondContact O-N 2.63Å; L271-A275 WeakPolarHBondContact O-CB 3.43Å; L271-A275 PolarHBondContact O-N 3.19Å; L271-L282 HydrophobicContact CD2-CD2 3.25Å
272	V	83.6	Confident	84	Confident	46 Å²	46	74.7 Å²	74.7	28%	0.279	38%	0.381	S	S	.	.	H	α-helix	trans	-63.8	-47.2	178.2	174.9	0	0	0	0	111.4	L268 R269 T274 A275 Q276	L268-V272 WeakPolarHBondContact O-CG2 3.43Å; L268-V272 PolarHBondContact O-N 2.99Å; R269-V272 PolarHBondContact O-N 3.48Å; V272-T274 PolarHBondContact O-N 3.07Å; V272-A275 PolarHBondContact O-N 3.25Å; V272-Q276 HydrophobicContact CG1-CG 4.48Å; V272-Q276 WeakPolarHBondContact O-CB 3.3Å; V272-Q276 VanDerWaalsContact O-CG 3.32Å; V272-Q276 WeakPolarHBondContact O-CG 3.47Å; V272-Q276 PolarHBondContact O-N 3.05Å
273	E	87.7	Confident	83.2	Confident	70 Å²	70	71.3 Å²	71.3	33%	0.327	36%	0.362	S	S	.	.	H	α-helix	trans	-60.7	-45.9	178	-72.2	174.7	175.8	0	0	111	R269 A275 Q276 E277	R269-E273 HydrophobicContact CG-CG 4.36Å; R269-E273 IonicContact CZ-OE1 3.53Å; R269-E273 IonicContact NE-OE1 2.79Å; R269-E273 PolarHBondContact NE-OE1 2.93Å; R269-E273 IonicContact NH2-OE1 3.34Å; R269-E273 PolarHBondContact NH2-OE1 3.37Å; R269-E273 WeakPolarHBondContact O-CG 3.31Å; R269-E273 PolarHBondContact O-N 3.15Å; E273-A275 VanDerWaalsContact C-N 3.35Å; E273-A275 PolarHBondContact O-N 3.46Å; E273-Q276 PolarHBondContact O-N 2.91Å; E273-E277 WeakPolarHBondContact O-CG 3.4Å; E273-E277 PolarHBondContact O-N 3.5Å
274	T	85.6	Confident	82.2	Confident	18 Å²	18	71.7 Å²	71.7	11%	0.11	36%	0.364	C	S	.	.	H	α-helix	trans	-64.1	-37.5	178.6	-54.5	0	0	0	0	112.4	Y154 M270 L271 V272 R278	Y154-T274 HydrophobicContact CD1-CG2 4.14Å; Y154-T274 HydrophobicContact CE1-CG2 3.72Å; M270-T274 VanDerWaalsContact O-CB 3.3Å; M270-T274 WeakPolarHBondContact O-CB 3.43Å; M270-T274 PolarHBondContact O-N 3.34Å; M270-T274 PolarHBondContact O-OG1 2.93Å; L271-T274 PolarHBondContact O-N 2.63Å; V272-T274 PolarHBondContact O-N 3.07Å; T274-R278 WeakPolarHBondContact O-CG 3.39Å; T274-R278 PolarHBondContact O-N 2.88Å
275	A	82	Confident	81.5	Confident	4 Å²	4	67.6 Å²	67.6	3%	0.033	34%	0.339	C	S	.	.	H	α-helix	trans	-70.9	-37.3	178.1	0	0	0	0	0	112	Y154 L271 V272 E273 R278 N279 E280 L282	Y154-A275 HydrophobicContact CE1-CB 4.44Å; L271-A275 WeakPolarHBondContact O-CB 3.43Å; L271-A275 PolarHBondContact O-N 3.19Å; V272-A275 PolarHBondContact O-N 3.25Å; E273-A275 VanDerWaalsContact C-N 3.35Å; E273-A275 PolarHBondContact O-N 3.46Å; A275-R278 PolarHBondContact O-N 2.96Å; A275-N279 PolarHBondContact O-N 2.9Å; A275-N279 VanDerWaalsContact O-N 3.12Å; A275-E280 PolarHBondContact O-N 2.91Å; A275-E280 VanDerWaalsContact O-N 3.13Å; A275-L282 HydrophobicContact CB-CD2 3.38Å; A275-L282 HydrophobicContact CB-CG 3.96Å
276	Q	83.1	Confident	81.1	Confident	131 Å²	131	61.8 Å²	61.8	61%	0.612	32%	0.316	S	S	*	.	H	α-helix	trans	-66	-44.4	173.7	-73.7	177.8	-15.5	0	0	111.6	V272 E273 R278 N279	V272-Q276 HydrophobicContact CG1-CG 4.48Å; V272-Q276 WeakPolarHBondContact O-CB 3.3Å; V272-Q276 VanDerWaalsContact O-CG 3.32Å; V272-Q276 WeakPolarHBondContact O-CG 3.47Å; V272-Q276 PolarHBondContact O-N 3.05Å; E273-Q276 PolarHBondContact O-N 2.91Å; Q276-R278 PolarHBondContact O-N 3.3Å; Q276-N279 PolarHBondContact O-N 3.43Å
277	E	88.2	Confident	80.8	Confident	155 Å²	155	63.2 Å²	63.2	72%	0.724	32%	0.323	S	S	*	.	H	α-helix	trans	-58.5	-33.8	175.7	-75.9	175.5	-178.2	0	0	112.8	E273	E273-E277 WeakPolarHBondContact O-CG 3.4Å; E273-E277 PolarHBondContact O-N 3.5Å
278	R	85.7	Confident	80.5	Confident	64 Å²	64	62.5 Å²	62.5	24%	0.242	32%	0.317	C	S	.	.	T	Hydrogen-bonded Turn	trans	-91	-5.9	-178.9	-65.7	178.4	-172.1	176	7.4	114.1	Y154 Y159 T274 A275 Q276 E280	Y154-R278 PolarHBondContact O-NH1 3.37Å; Y159-R278 PolarHBondContact OH-NH1 2.96Å; T274-R278 WeakPolarHBondContact O-CG 3.39Å; T274-R278 PolarHBondContact O-N 2.88Å; A275-R278 PolarHBondContact O-N 2.96Å; Q276-R278 PolarHBondContact O-N 3.3Å; R278-E280 HydrophobicContact CB-CB 4.37Å; R278-E280 HydrophobicContact CB-CG 3.93Å; R278-E280 PolarHBondContact O-N 2.98Å
279	N	77.1	Confident	80.4	Confident	155 Å²	155	61.6 Å²	61.6	83%	0.829	32%	0.315	S	S	*	.	T	Hydrogen-bonded Turn	trans	51.5	33	-169.5	-67.6	-48.7	0	0	0	113.4	A275 Q276	A275-N279 PolarHBondContact O-N 2.9Å; A275-N279 VanDerWaalsContact O-N 3.12Å; Q276-N279 PolarHBondContact O-N 3.43Å
280	E	76.2	Confident	79.5	Confident	78 Å²	78	57.5 Å²	57.5	36%	0.364	30%	0.301	S	S	.	.	P	Polyproline II helix	trans	-94.1	135.8	178.3	-73.6	175.5	-175.1	0	0	110.2	Y154 Y159 A275 R278 L282	Y154-E280 PolarHBondContact OH-OE2 3.01Å; Y154-E280 VanDerWaalsContact OH-OE2 3.1Å; Y159-E280 PolarHBondContact OH-OE1 3.48Å; Y159-E280 VanDerWaalsContact OH-OE1 3.06Å; Y159-E280 PolarHBondContact OH-OE2 3.23Å; A275-E280 PolarHBondContact O-N 2.91Å; A275-E280 VanDerWaalsContact O-N 3.13Å; R278-E280 HydrophobicContact CB-CB 4.37Å; R278-E280 HydrophobicContact CB-CG 3.93Å; R278-E280 PolarHBondContact O-N 2.98Å; E280-L282 PolarHBondContact O-N 3.32Å
281	T	71.7	Confident	78.4	Confident	119 Å²	119	56.2 Å²	56.2	73%	0.73	30%	0.296	S	S	*	.	P	Polyproline II helix	trans	-70.6	128.3	169	51	0	0	0	0	109.5
282	L	69.9	Low	76.4	Confident	42 Å²	42	58 Å²	58	22%	0.22	30%	0.304	C	S	.	.	P	Polyproline II helix	trans	-58.7	152.9	173.3	-68.5	174	0	0	0	111.6	L271 A275 E280 I287	L271-L282 HydrophobicContact CD2-CD2 3.25Å; A275-L282 HydrophobicContact CB-CD2 3.38Å; A275-L282 HydrophobicContact CB-CG 3.96Å; E280-L282 PolarHBondContact O-N 3.32Å; L282-I287 HydrophobicContact CB-CD1 3.25Å; L282-I287 HydrophobicContact CD1-CD1 3.63Å; L282-I287 HydrophobicContact CG-CD1 4.07Å
283	F	72.7	Confident	74.3	Confident	19 Å²	19	60.5 Å²	60.5	8%	0.083	32%	0.32	C	S	.	.	P	Polyproline II helix	trans	-47.1	125.3	-167.3	-57.9	-71.8	0	0	0	114.1	L150 Y154 I162 L166 A285 L286	L150-F283 HydrophobicContact CD2-CE2 4.38Å; Y154-F283 HydrophobicContact CD2-CE2 4.24Å; Y154-F283 AromaticContact CD2-CZ 3.78Å; Y154-F283 HydrophobicContact CD2-CZ 3.78Å; Y154-F283 HydrophobicContact CE2-CZ 4.07Å; I162-F283 HydrophobicContact CB-CE1 4.29Å; I162-F283 HydrophobicContact CB-CZ 4.26Å; I162-F283 HydrophobicContact CD1-CZ 3.98Å; I162-F283 HydrophobicContact CG2-CD1 4.15Å; I162-F283 HydrophobicContact CG2-CE1 3.45Å; I162-F283 VanDerWaalsContact CG2-CE1 3.45Å; I162-F283 HydrophobicContact CG2-CE2 3.97Å; I162-F283 HydrophobicContact CG2-CZ 3.37Å; L166-F283 HydrophobicContact CD1-CB 3.69Å; L166-F283 HydrophobicContact CD1-CD1 3.55Å; L166-F283 HydrophobicContact CD1-CD2 4.42Å; L166-F283 HydrophobicContact CD1-CE1 4.34Å; L166-F283 HydrophobicContact CD1-CG 3.62Å; F283-A285 PolarHBondContact O-N 3.39Å; F283-A285 VanDerWaalsContact O-N 3.1Å; F283-L286 HydrophobicContact CB-CB 4.43Å; F283-L286 HydrophobicContact CB-CD1 4Å; F283-L286 HydrophobicContact CD2-CD1 4.13Å; F283-L286 HydrophobicContact CG-CD1 4.35Å; F283-L286 PolarHBondContact O-N 2.98Å; F283-L286 VanDerWaalsContact O-N 3.14Å
284	P	70.3	Confident	71.5	Confident	61 Å²	61	64.4 Å²	64.4	40%	0.396	33%	0.332	S	S	.	.	T	Hydrogen-bonded Turn	trans	-64.7	-20.9	-173.6	26.1	-35.3	0	0	0	113.8
285	A	73.4	Confident	68.9	Low	13 Å²	13	70.6 Å²	70.6	11%	0.107	36%	0.363	C	S	.	.	T	Hydrogen-bonded Turn	trans	-84.4	-12.8	-179.7	0	0	0	0	0	114.5	I213 F283 L325	I213-A285 HydrophobicContact CG2-CB 3.64Å; F283-A285 PolarHBondContact O-N 3.39Å; F283-A285 VanDerWaalsContact O-N 3.1Å; A285-L325 WeakPolarHBondContact O-CD1 3.45Å
286	L	79.4	Confident	66.6	Low	71 Å²	71	75.7 Å²	75.7	37%	0.372	39%	0.394	S	S	.	.	T	Hydrogen-bonded Turn	trans	-110.5	-14.2	-173.2	-88.9	146.9	0	0	0	113.8	L166 F283 L325	L166-L286 HydrophobicContact CD1-CD1 4.27Å; L166-L286 HydrophobicContact CD2-CD1 3.49Å; L166-L286 VanDerWaalsContact CD2-CD1 3.49Å; L166-L286 HydrophobicContact CD2-CG 4.19Å; F283-L286 HydrophobicContact CB-CB 4.43Å; F283-L286 HydrophobicContact CB-CD1 4Å; F283-L286 HydrophobicContact CD2-CD1 4.13Å; F283-L286 HydrophobicContact CG-CD1 4.35Å; F283-L286 PolarHBondContact O-N 2.98Å; F283-L286 VanDerWaalsContact O-N 3.14Å; L286-L325 WeakPolarHBondContact O-CG 3.32Å; L286-L325 PolarHBondContact O-N 2.88Å
287	I	81.6	Confident	64.4	Low	33 Å²	33	75.4 Å²	75.4	17%	0.169	40%	0.396	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.5	127.2	-172.5	-60.5	177.7	0	0	0	109.4	L282 K322	L282-I287 HydrophobicContact CB-CD1 3.25Å; L282-I287 HydrophobicContact CD1-CD1 3.63Å; L282-I287 HydrophobicContact CG-CD1 4.07Å; I287-K322 HydrophobicContact CG2-CB 3.63Å; I287-K322 HydrophobicContact CG2-CD 4.33Å; I287-K322 HydrophobicContact CG2-CG 4.07Å
288	Y	81.6	Confident	62.2	Low	9 Å²	9	74.2 Å²	74.2	4%	0.035	39%	0.392	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-74.7	123.3	168.6	-175.7	-89.8	0	0	0	110	P88 Q223 L226 K322 L323 F328	P88-Y288 HydrophobicContact CB-CE1 4.25Å; P88-Y288 HydrophobicContact CB-CE2 3.83Å; P88-Y288 WeakPolarHBondContact CB-OH 3.14Å; P88-Y288 HydrophobicContact CG-CE1 3.77Å; P88-Y288 HydrophobicContact CG-CE2 4.28Å; Q223-Y288 HydrophobicContact CB-CE2 3.72Å; Q223-Y288 HydrophobicContact CG-CD2 4.44Å; Q223-Y288 HydrophobicContact CG-CE2 3.58Å; Q223-Y288 PolarHBondContact NE2-OH 3.4Å; Q223-Y288 PolarHBondContact OE1-OH 3.12Å; L226-Y288 HydrophobicContact CB-CD2 4.39Å; L226-Y288 HydrophobicContact CD1-CD2 4.26Å; Y288-K322 VanDerWaalsContact O-CA 3.29Å; Y288-K322 WeakPolarHBondContact O-CA 3.31Å; Y288-L323 PolarHBondContact N-O 3.17Å; Y288-L323 PolarHBondContact O-N 3.36Å; Y288-F328 HydrophobicContact CD1-CZ 4.15Å; Y288-F328 HydrophobicContact CD2-CZ 4.13Å; Y288-F328 HydrophobicContact CG-CE2 4.05Å; Y288-F328 AromaticContact CG-CZ 3.84Å; Y288-F328 HydrophobicContact CG-CZ 3.84Å
289	S	80.5	Confident	60.1	Low	35 Å²	35	75.3 Å²	75.3	25%	0.245	42%	0.415	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-110.5	124	175.8	-179.1	0	0	0	0	110.4	Q223 T291	Q223-S289 PolarHBondContact NE2-O 3.48Å; S289-T291 VanDerWaalsContact C-N 3.31Å; S289-T291 WeakPolarHBondContact OG-CB 3.25Å; S289-T291 PolarHBondContact OG-N 2.67Å; S289-T291 PolarHBondContact OG-OG1 2.61Å
290	S	68.2	Low	58.5	Low	4 Å²	4	77 Å²	77	3%	0.028	42%	0.418	C	S	.	.			trans	-87.2	0.6	172.6	74.6	0	0	0	0	113.9	M292 V321	S290-M292 PolarHBondContact O-N 2.86Å; S290-V321 PolarHBondContact N-O 3.46Å; S290-V321 PolarHBondContact OG-N 3.32Å; S290-V321 VanDerWaalsContact OG-N 3.12Å; S290-V321 PolarHBondContact OG-O 2.9Å
291	T	62.5	Low	57.2	Low	32 Å²	32	75.6 Å²	75.6	20%	0.196	43%	0.425	C	S	.	.			trans	-63.2	98	-172	-44.9	0	0	0	0	111.7	L219 S289 V293 A317 G320	L219-T291 WeakPolarHBondContact CD1-O 3.45Å; S289-T291 VanDerWaalsContact C-N 3.31Å; S289-T291 WeakPolarHBondContact OG-CB 3.25Å; S289-T291 PolarHBondContact OG-N 2.67Å; S289-T291 PolarHBondContact OG-OG1 2.61Å; T291-V293 PolarHBondContact O-N 3.32Å; T291-A317 WeakPolarHBondContact CG2-O 3.45Å; T291-G320 WeakPolarHBondContact OG1-CA 3.24Å
292	M	44.2	Very low	56.4	Low	58 Å²	58	75 Å²	75	29%	0.286	42%	0.417	S	S	.	.			trans	-68.6	96.2	-179.4	-60.8	-168.9	80.3	0	0	111	M84 R220 S290 W294	M84-M292 HydrophobicContact CE-CG 4.38Å; M84-M292 HydrophobicContact CE-SD 4.09Å; R220-M292 VanDerWaalsContact NH2-CE 3.33Å; S290-M292 PolarHBondContact O-N 2.86Å; M292-W294 PolarHBondContact O-N 3.4Å
293	V	38.2	Very low	55.9	Low	100 Å²	100	77.2 Å²	77.2	61%	0.606	43%	0.434	S	S	*	.			trans	-83.8	98.5	165	-177.9	0	0	0	0	107.8	T291 L295	T291-V293 PolarHBondContact O-N 3.32Å; V293-L295 HydrophobicContact CG1-CB 4.45Å; V293-L295 HydrophobicContact CG1-CD1 4.41Å; V293-L295 PolarHBondContact O-N 3.28Å
294	W	29.7	Very low	55.2	Low	152 Å²	152	83.5 Å²	83.5	58%	0.576	46%	0.464	S	S	*	.			trans	-79.3	96.7	168.4	-90.9	95.1	0	0	0	109.2	M292 V296 N297	M292-W294 PolarHBondContact O-N 3.4Å; W294-V296 VanDerWaalsContact CE3-O 3.31Å; W294-V296 WeakPolarHBondContact CZ3-O 3.23Å; W294-N297 HydrophobicContact CE3-CB 4.19Å; W294-N297 HydrophobicContact CZ3-CB 3.68Å; W294-N297 WeakPolarHBondContact CZ3-ND2 3.13Å
295	L	31	Very low	54.4	Low	147 Å²	147	83.1 Å²	83.1	77%	0.77	47%	0.466	S	S	*	.			trans	-109	2.8	168.1	-136.9	143.7	0	0	0	112.7	V293	V293-L295 HydrophobicContact CG1-CB 4.45Å; V293-L295 HydrophobicContact CG1-CD1 4.41Å; V293-L295 PolarHBondContact O-N 3.28Å
296	V	33	Very low	53.2	Low	112 Å²	112	86 Å²	86	68%	0.679	48%	0.477	S	S	*	.	S	Bend	trans	-137.4	86.3	-172.6	-174.1	0	0	0	0	109.9	W294	W294-V296 VanDerWaalsContact CE3-O 3.31Å; W294-V296 WeakPolarHBondContact CZ3-O 3.23Å
297	N	37.9	Very low	52	Low	124 Å²	124	92.4 Å²	92.4	66%	0.663	50%	0.496	S	S	*	.			trans	170.5	16.5	152.6	-84.9	-4.1	0	0	0	112.6	W294 A299	W294-N297 HydrophobicContact CE3-CB 4.19Å; W294-N297 HydrophobicContact CZ3-CB 3.68Å; W294-N297 WeakPolarHBondContact CZ3-ND2 3.13Å; N297-A299 PolarHBondContact O-N 2.86Å; N297-A299 VanDerWaalsContact O-N 3.07Å
298	M	40.8	Very low	50.5	Low	131 Å²	131	100.9 Å²	100.9	65%	0.645	53%	0.526	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.4	28.5	-179.4	-68.4	-141.2	158.9	0	0	114.8
299	A	42.8	Very low	49	Very low	87 Å²	87	104.6 Å²	104.6	72%	0.719	55%	0.55	S	S	*	.	T	Hydrogen-bonded Turn	trans	-94.4	-14.5	-173.5	0	0	0	0	0	115.6	N297	N297-A299 PolarHBondContact O-N 2.86Å; N297-A299 VanDerWaalsContact O-N 3.07Å
300	E	42.2	Very low	47.3	Very low	189 Å²	189	105.7 Å²	105.7	88%	0.883	56%	0.557	S	S	*	*	S	Bend	trans	-153.5	112.3	178.1	-112.1	132.6	148	0	0	111
301	G	49.3	Very low	46.2	Very low	50 Å²	50	113.5 Å²	113.5	52%	0.515	59%	0.591	S	S	.	*	S	Bend	trans	155.2	118.5	170.8	0	0	0	0	0	114.7
302	D	55.9	Low	45.3	Very low	106 Å²	106	116.8 Å²	116.8	57%	0.567	61%	0.607	S	S	*	*			trans	1.4	119	168.9	-145.8	-16.2	0	0	0	118.8	E304 A305 Q306	D302-E304 PolarHBondContact O-N 3.37Å; D302-E304 VanDerWaalsContact O-N 3.13Å; D302-A305 HydrophobicContact CB-CB 4.2Å; D302-A305 PolarHBondContact O-N 2.96Å; D302-A305 VanDerWaalsContact O-N 3.11Å; D302-Q306 PolarHBondContact O-N 2.89Å
303	P	58.8	Low	45.3	Very low	88 Å²	88	116.2 Å²	116.2	57%	0.571	61%	0.609	S	S	*	*	H	α-helix	trans	-58.9	-25.1	-179.1	20.5	-33	0	0	0	115	R307	P303-R307 PolarHBondContact O-N 3.2Å
304	E	57	Low	45.4	Very low	151 Å²	151	117.2 Å²	117.2	71%	0.706	61%	0.605	S	S	*	*	H	α-helix	trans	-77.5	-37.1	176.1	-74.6	-167.8	151.4	0	0	112.9	D302 Q306 R307 R308	D302-E304 PolarHBondContact O-N 3.37Å; D302-E304 VanDerWaalsContact O-N 3.13Å; E304-Q306 VanDerWaalsContact C-N 3.3Å; E304-R307 PolarHBondContact O-N 2.91Å; E304-R308 PolarHBondContact O-N 3.42Å
305	A	54.7	Low	46	Very low	54 Å²	54	117.6 Å²	117.6	45%	0.446	61%	0.608	S	S	.	*	H	α-helix	trans	-65.3	-38.1	171	0	0	0	0	0	110.4	D302 R307 R308 V309	D302-A305 HydrophobicContact CB-CB 4.2Å; D302-A305 PolarHBondContact O-N 2.96Å; D302-A305 VanDerWaalsContact O-N 3.11Å; A305-R307 PolarHBondContact O-N 3.19Å; A305-R308 PolarHBondContact O-N 3.06Å; A305-V309 VanDerWaalsContact O-CB 3.31Å; A305-V309 WeakPolarHBondContact O-CB 3.34Å; A305-V309 WeakPolarHBondContact O-CG2 3.28Å; A305-V309 PolarHBondContact O-N 3.36Å
306	Q	48.2	Very low	46.6	Very low	73 Å²	73	113.1 Å²	113.1	34%	0.341	58%	0.584	S	S	.	*	H	α-helix	trans	-61.2	-37.8	174.4	-92	168.5	-18	0	0	113.5	D302 E304 S310	D302-Q306 PolarHBondContact O-N 2.89Å; E304-Q306 VanDerWaalsContact C-N 3.3Å; Q306-S310 WeakPolarHBondContact O-CA 3.26Å; Q306-S310 WeakPolarHBondContact O-CB 3.35Å; Q306-S310 PolarHBondContact O-N 2.98Å
307	R	53.7	Low	47.1	Very low	205 Å²	205	109.3 Å²	109.3	77%	0.774	57%	0.565	S	S	*	*	H	α-helix	trans	-70.6	-41.5	178	-77.6	-177.8	178.9	177.8	0.6	113	P303 E304 A305 S310 K311	P303-R307 PolarHBondContact O-N 3.2Å; E304-R307 PolarHBondContact O-N 2.91Å; A305-R307 PolarHBondContact O-N 3.19Å; R307-S310 PolarHBondContact O-N 2.92Å; R307-K311 PolarHBondContact O-N 3.42Å
308	R	49.9	Very low	47.7	Very low	211 Å²	211	110.7 Å²	110.7	80%	0.796	57%	0.567	S	S	*	*	H	α-helix	trans	-69.7	-40.7	177.8	-69.1	-173.8	178.2	-169	0.3	111.9	E304 A305 N312	E304-R308 PolarHBondContact O-N 3.42Å; A305-R308 PolarHBondContact O-N 3.06Å; R308-N312 PolarHBondContact O-N 3.31Å
309	V	50.3	Low	48.5	Very low	88 Å²	88	112.3 Å²	112.3	53%	0.533	57%	0.566	S	S	.	*	H	α-helix	trans	-68.7	-40.6	174	176.1	0	0	0	0	110.5	A305 S313	A305-V309 VanDerWaalsContact O-CB 3.31Å; A305-V309 WeakPolarHBondContact O-CB 3.34Å; A305-V309 WeakPolarHBondContact O-CG2 3.28Å; A305-V309 PolarHBondContact O-N 3.36Å; V309-S313 WeakPolarHBondContact O-CA 3.18Å; V309-S313 WeakPolarHBondContact O-CB 3.44Å; V309-S313 PolarHBondContact O-N 3.49Å
310	S	44.6	Very low	49.4	Very low	58 Å²	58	109.3 Å²	109.3	41%	0.406	54%	0.543	S	S	.	.	H	α-helix	trans	-66.9	-40.4	-179.3	-171.2	0	0	0	0	112.6	Q306 R307 S313 K314	Q306-S310 WeakPolarHBondContact O-CA 3.26Å; Q306-S310 WeakPolarHBondContact O-CB 3.35Å; Q306-S310 PolarHBondContact O-N 2.98Å; R307-S310 PolarHBondContact O-N 2.92Å; S310-S313 PolarHBondContact O-N 3.48Å; S310-K314 WeakPolarHBondContact O-CB 3.21Å; S310-K314 PolarHBondContact O-N 2.73Å
311	K	45	Very low	51	Low	168 Å²	168	101.8 Å²	101.8	73%	0.73	51%	0.51	S	S	*	.	H	α-helix	trans	-67	-43.4	178.3	-137.5	179.5	-175	-172.8	0	112.5	R307	R307-K311 PolarHBondContact O-N 3.42Å
312	N	44.8	Very low	52.5	Low	101 Å²	101	105 Å²	105	54%	0.54	51%	0.51	S	S	.	.	H	α-helix	trans	-72.4	-32.4	175.8	-115.6	-17.1	0	0	0	112.3	R308 N316	R308-N312 PolarHBondContact O-N 3.31Å; N312-N316 WeakPolarHBondContact O-CB 3.34Å; N312-N316 PolarHBondContact O-N 3.21Å; N312-N316 PolarHBondContact O-ND2 3.44Å
313	S	44.3	Very low	53.7	Low	46 Å²	46	100.6 Å²	100.6	32%	0.322	49%	0.486	S	S	.	.	H	α-helix	trans	-82.8	-33.5	-177	-162.4	0	0	0	0	112.7	V309 S310 N316 A317	V309-S313 WeakPolarHBondContact O-CA 3.18Å; V309-S313 WeakPolarHBondContact O-CB 3.44Å; V309-S313 PolarHBondContact O-N 3.49Å; S310-S313 PolarHBondContact O-N 3.48Å; S313-N316 CarbonylContact O-C 3.48Å; S313-N316 PolarHBondContact O-N 3.05Å; S313-A317 VanDerWaalsContact O-CB 3.23Å; S313-A317 WeakPolarHBondContact O-CB 3.42Å; S313-A317 PolarHBondContact O-N 3.26Å
314	K	40.2	Very low	55	Low	120 Å²	120	97.7 Å²	97.7	52%	0.522	47%	0.472	S	S	.	.	H	α-helix	trans	-64.8	-39.5	175	-154.1	177.4	-171.2	-171.8	0	111	S310 A317 E318	S310-K314 WeakPolarHBondContact O-CB 3.21Å; S310-K314 PolarHBondContact O-N 2.73Å; K314-A317 PolarHBondContact O-N 2.87Å; K314-E318 PolarHBondContact O-N 2.91Å
315	Y	41.8	Very low	56.5	Low	161 Å²	161	91.1 Å²	91.1	63%	0.631	44%	0.442	S	S	*	.	H	α-helix	trans	-66.3	-39.2	169.6	-99.4	-89.4	0	0	0	113.4	A317	Y315-A317 VanDerWaalsContact C-N 3.29Å; Y315-A317 PolarHBondContact O-N 3.35Å
316	N	43	Very low	58.2	Low	52 Å²	52	90 Å²	90	28%	0.278	44%	0.436	S	S	.	.	H	α-helix	trans	-68.6	-25.8	175.1	-89.8	-76.9	0	0	0	113.3	Y77 K80 N312 S313	Y77-N316 VanDerWaalsContact CE1-OD1 3.31Å; Y77-N316 WeakPolarHBondContact CE1-OD1 3.45Å; K80-N316 PolarHBondContact NZ-OD1 3.47Å; N312-N316 WeakPolarHBondContact O-CB 3.34Å; N312-N316 PolarHBondContact O-N 3.21Å; N312-N316 PolarHBondContact O-ND2 3.44Å; S313-N316 CarbonylContact O-C 3.48Å; S313-N316 PolarHBondContact O-N 3.05Å
317	A	43.5	Very low	60.3	Low	33 Å²	33	87.3 Å²	87.3	27%	0.273	42%	0.424	S	S	.	.	H	α-helix	trans	-82.4	-20.7	-175.1	0	0	0	0	0	113.2	T291 S313 K314 Y315	T291-A317 WeakPolarHBondContact CG2-O 3.45Å; S313-A317 VanDerWaalsContact O-CB 3.23Å; S313-A317 WeakPolarHBondContact O-CB 3.42Å; S313-A317 PolarHBondContact O-N 3.26Å; K314-A317 PolarHBondContact O-N 2.87Å; Y315-A317 VanDerWaalsContact C-N 3.29Å; Y315-A317 PolarHBondContact O-N 3.35Å
318	E	50.3	Low	62.2	Low	152 Å²	152	77.6 Å²	77.6	71%	0.71	39%	0.387	S	S	*	.	S	Bend	trans	-89.3	-13.7	-174.2	-75	-179.9	179	0	0	114.4	K314	K314-E318 PolarHBondContact O-N 2.91Å
319	R	58	Low	64.4	Low	166 Å²	166	68.6 Å²	68.6	63%	0.626	35%	0.354	S	S	*	.			trans	-116.6	44.5	-175.9	-64.1	-170.5	179.2	177.3	2.6	113.8	H81	H81-R319 PolarHBondContact CE1-O 3.44Å; H81-R319 PolarHBondContact NE2-O 2.91Å
320	G	62.8	Low	66.6	Low	23 Å²	23	65.6 Å²	65.6	24%	0.237	33%	0.334	C	S	.	.			trans	-62.4	140.5	170.4	0	0	0	0	0	111.7	T291	T291-G320 WeakPolarHBondContact OG1-CA 3.24Å
321	V	74.4	Confident	69	Low	32 Å²	32	62.8 Å²	62.8	19%	0.194	32%	0.315	C	S	.	.			trans	-86.6	137.1	173.4	-179.8	0	0	0	0	108.7	H81 L85 S290	H81-V321 HydrophobicContact CB-CG2 3.81Å; L85-V321 HydrophobicContact CD1-CB 4.44Å; L85-V321 HydrophobicContact CD1-CG1 3.66Å; L85-V321 HydrophobicContact CD2-CG1 4.24Å; L85-V321 HydrophobicContact CG-CG1 4.22Å; S290-V321 PolarHBondContact N-O 3.46Å; S290-V321 PolarHBondContact OG-N 3.32Å; S290-V321 VanDerWaalsContact OG-N 3.12Å; S290-V321 PolarHBondContact OG-O 2.9Å
322	K	81	Confident	71.5	Confident	116 Å²	116	54.9 Å²	54.9	50%	0.504	28%	0.281	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-108.9	128.8	178.1	-70.4	179.4	-174.1	174.5	0	108.5	I287 Y288	I287-K322 HydrophobicContact CG2-CB 3.63Å; I287-K322 HydrophobicContact CG2-CD 4.33Å; I287-K322 HydrophobicContact CG2-CG 4.07Å; Y288-K322 VanDerWaalsContact O-CA 3.29Å; Y288-K322 WeakPolarHBondContact O-CA 3.31Å
323	L	82.3	Confident	74	Confident	14 Å²	14	50.2 Å²	50.2	7%	0.073	26%	0.256	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-125.1	141.6	177.6	-169	66.8	0	0	0	109.4	L85 V89 Y288 D327 F328 A376	L85-L323 HydrophobicContact CD2-CB 3.86Å; L85-L323 HydrophobicContact CD2-CD2 4.05Å; V89-L323 HydrophobicContact CG2-CD2 4.15Å; Y288-L323 PolarHBondContact N-O 3.17Å; Y288-L323 PolarHBondContact O-N 3.36Å; L323-D327 HydrophobicContact CD1-CB 4.27Å; L323-D327 WeakPolarHBondContact CD1-OD2 3.37Å; L323-D327 HydrophobicContact CD2-CB 4.31Å; L323-D327 HydrophobicContact CG-CB 4.11Å; L323-D327 WeakPolarHBondContact CG-OD2 3.3Å; L323-F328 HydrophobicContact CB-CE2 4.07Å; L323-F328 HydrophobicContact CD2-CD2 4.26Å; L323-F328 HydrophobicContact CD2-CE2 3.56Å; L323-F328 HydrophobicContact CD2-CZ 3.89Å; L323-F328 HydrophobicContact CG-CE2 3.94Å; L323-A376 HydrophobicContact CD1-CB 4.15Å
324	G	85.8	Confident	76.5	Confident	27 Å²	27	48 Å²	48	28%	0.278	24%	0.241	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-72.2	142.6	179.7	0	0	0	0	0	110.5	G326 D327 F328	G324-G326 PolarHBondContact O-N 3.06Å; G324-D327 PolarHBondContact N-OD2 3.28Å; G324-D327 VanDerWaalsContact N-OD2 3.16Å; G324-D327 WeakPolarHBondContact O-CB 3.25Å; G324-D327 PolarHBondContact O-N 3.29Å; G324-D327 VanDerWaalsContact O-N 3.15Å; G324-F328 WeakPolarHBondContact O-CD2 3.27Å
325	L	87.9	Confident	79.2	Confident	13 Å²	13	42.5 Å²	42.5	7%	0.068	22%	0.217	C	C	.	.	H	α-helix	trans	-63.3	-25	173.1	-65.3	-176.4	0	0	0	112.7	L226 A285 L286 D327 F328 I329	L226-L325 HydrophobicContact CB-CD2 3.98Å; L226-L325 HydrophobicContact CD2-CD1 3.73Å; L226-L325 HydrophobicContact CD2-CD2 4.06Å; L226-L325 HydrophobicContact CD2-CG 4.39Å; L226-L325 HydrophobicContact CG-CD2 4.47Å; A285-L325 WeakPolarHBondContact O-CD1 3.45Å; L286-L325 WeakPolarHBondContact O-CG 3.32Å; L286-L325 PolarHBondContact O-N 2.88Å; L325-D327 PolarHBondContact O-N 3.41Å; L325-F328 HydrophobicContact CD2-CD2 4.42Å; L325-F328 WeakPolarHBondContact O-CB 3.47Å; L325-F328 PolarHBondContact O-N 3.47Å; L325-I329 VanDerWaalsContact O-CG1 3.29Å; L325-I329 WeakPolarHBondContact O-CG1 3.32Å; L325-I329 PolarHBondContact O-N 3.46Å
326	G	90.4	Very high	81.7	Confident	30 Å²	30	34.8 Å²	34.8	31%	0.309	19%	0.187	S	C	.	.	H	α-helix	trans	-54.2	-40.9	172.9	0	0	0	0	0	112.2	G324 F328 I329 F330	G324-G326 PolarHBondContact O-N 3.06Å; G326-F328 PolarHBondContact O-N 3.26Å; G326-I329 PolarHBondContact O-N 2.94Å; G326-F330 WeakPolarHBondContact O-CD2 3.43Å; G326-F330 PolarHBondContact O-N 2.9Å
327	D	91.9	Very high	84.2	Confident	17 Å²	17	32.9 Å²	32.9	9%	0.091	18%	0.176	C	C	.	.	H	α-helix	trans	-58.8	-50.4	177.7	-55.3	-45.1	0	0	0	110.9	L323 G324 L325 I329 F330 Y331 L377	L323-D327 HydrophobicContact CD1-CB 4.27Å; L323-D327 WeakPolarHBondContact CD1-OD2 3.37Å; L323-D327 HydrophobicContact CD2-CB 4.31Å; L323-D327 HydrophobicContact CG-CB 4.11Å; L323-D327 WeakPolarHBondContact CG-OD2 3.3Å; G324-D327 PolarHBondContact N-OD2 3.28Å; G324-D327 VanDerWaalsContact N-OD2 3.16Å; G324-D327 WeakPolarHBondContact O-CB 3.25Å; G324-D327 PolarHBondContact O-N 3.29Å; G324-D327 VanDerWaalsContact O-N 3.15Å; L325-D327 PolarHBondContact O-N 3.41Å; D327-I329 VanDerWaalsContact C-N 3.31Å; D327-I329 PolarHBondContact O-N 2.87Å; D327-F330 PolarHBondContact O-N 2.9Å; D327-Y331 HydrophobicContact CB-CD2 4.39Å; D327-Y331 HydrophobicContact CB-CE2 3.85Å; D327-Y331 VanDerWaalsContact O-CB 3.28Å; D327-Y331 WeakPolarHBondContact O-CB 3.45Å; D327-Y331 WeakPolarHBondContact O-CD2 3.36Å; D327-Y331 PolarHBondContact O-N 3.42Å; D327-L377 HydrophobicContact CB-CD2 4.42Å; D327-L377 WeakPolarHBondContact OD1-CG 3.19Å
328	F	94.1	Very high	86.7	Confident	2 Å²	2	31.3 Å²	31.3	1%	0.009	16%	0.163	C	C	.	.	H	α-helix	trans	-58.4	-43.1	176.9	-68.6	-97	0	0	0	112.3	P88 V89 C92 Y288 L323 G324 L325 G326 S332	P88-F328 HydrophobicContact CB-CE1 3.77Å; P88-F328 HydrophobicContact CB-CZ 4.19Å; P88-F328 HydrophobicContact CG-CE1 4.08Å; P88-F328 HydrophobicContact CG-CZ 4.16Å; V89-F328 HydrophobicContact CB-CD1 4.48Å; V89-F328 HydrophobicContact CB-CE1 4.24Å; V89-F328 HydrophobicContact CG2-CD1 3.86Å; V89-F328 HydrophobicContact CG2-CE1 3.46Å; V89-F328 VanDerWaalsContact CG2-CE1 3.46Å; V89-F328 HydrophobicContact CG2-CZ 3.88Å; C92-F328 HydrophobicContact CB-CD1 4.16Å; Y288-F328 HydrophobicContact CD1-CZ 4.15Å; Y288-F328 HydrophobicContact CD2-CZ 4.13Å; Y288-F328 HydrophobicContact CG-CE2 4.05Å; Y288-F328 AromaticContact CG-CZ 3.84Å; Y288-F328 HydrophobicContact CG-CZ 3.84Å; L323-F328 HydrophobicContact CB-CE2 4.07Å; L323-F328 HydrophobicContact CD2-CD2 4.26Å; L323-F328 HydrophobicContact CD2-CE2 3.56Å; L323-F328 HydrophobicContact CD2-CZ 3.89Å; L323-F328 HydrophobicContact CG-CE2 3.94Å; G324-F328 WeakPolarHBondContact O-CD2 3.27Å; L325-F328 HydrophobicContact CD2-CD2 4.42Å; L325-F328 WeakPolarHBondContact O-CB 3.47Å; L325-F328 PolarHBondContact O-N 3.47Å; G326-F328 PolarHBondContact O-N 3.26Å; F328-S332 VanDerWaalsContact O-CB 3.25Å; F328-S332 WeakPolarHBondContact O-CB 3.29Å; F328-S332 PolarHBondContact O-N 2.99Å; F328-S332 PolarHBondContact O-OG 2.92Å
329	I	95.6	Very high	88.7	Confident	21 Å²	21	24.2 Å²	24.2	11%	0.108	13%	0.13	C	C	.	.	H	α-helix	trans	-64	-54.1	-179.2	-65.3	164.4	0	0	0	109.8	M233 F237 L325 G326 D327 Y331 S332 V333	M233-I329 HydrophobicContact CB-CD1 3.85Å; M233-I329 HydrophobicContact CB-CG1 3.94Å; M233-I329 HydrophobicContact CB-CG2 4.3Å; M233-I329 HydrophobicContact CG-CD1 4.21Å; F237-I329 HydrophobicContact CD2-CG2 3.73Å; F237-I329 HydrophobicContact CE2-CG2 3.89Å; L325-I329 VanDerWaalsContact O-CG1 3.29Å; L325-I329 WeakPolarHBondContact O-CG1 3.32Å; L325-I329 PolarHBondContact O-N 3.46Å; G326-I329 PolarHBondContact O-N 2.94Å; D327-I329 VanDerWaalsContact C-N 3.31Å; D327-I329 PolarHBondContact O-N 2.87Å; I329-Y331 PolarHBondContact O-N 3.5Å; I329-S332 PolarHBondContact O-N 3.3Å; I329-V333 HydrophobicContact CG2-CG2 4.31Å; I329-V333 VanDerWaalsContact O-CG2 3.25Å; I329-V333 WeakPolarHBondContact O-CG2 3.23Å; I329-V333 PolarHBondContact O-N 2.97Å
330	F	96.1	Very high	90.4	Very high	25 Å²	25	17.9 Å²	17.9	11%	0.11	11%	0.113	C	C	.	.	H	α-helix	trans	-70.2	-34.4	-175	-68.5	-63	0	0	0	113.2	L250 I253 G326 D327 S332 V333 L334 L377 I381	L250-F330 HydrophobicContact CD2-CB 4.11Å; L250-F330 HydrophobicContact CD2-CD1 3.78Å; L250-F330 HydrophobicContact CD2-CG 4.37Å; I253-F330 HydrophobicContact CD1-CD2 4.34Å; I253-F330 HydrophobicContact CD1-CE1 3.81Å; I253-F330 HydrophobicContact CD1-CE2 3.49Å; I253-F330 VanDerWaalsContact CD1-CE2 3.49Å; I253-F330 HydrophobicContact CD1-CZ 3.19Å; I253-F330 HydrophobicContact CG2-CD1 4.35Å; I253-F330 HydrophobicContact CG2-CE1 4.37Å; G326-F330 WeakPolarHBondContact O-CD2 3.43Å; G326-F330 PolarHBondContact O-N 2.9Å; D327-F330 PolarHBondContact O-N 2.9Å; F330-S332 VanDerWaalsContact C-N 3.34Å; F330-V333 PolarHBondContact O-N 2.83Å; F330-L334 PolarHBondContact O-N 3.01Å; F330-L377 HydrophobicContact CB-CD2 3.92Å; F330-L377 HydrophobicContact CD2-CD1 3.97Å; F330-L377 HydrophobicContact CD2-CD2 4.3Å; F330-I381 HydrophobicContact CB-CD1 4.46Å
331	Y	96.8	Very high	91.5	Very high	0 Å²	0	18.9 Å²	18.9	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-62	-44.6	171.4	-63.9	-19.5	0	0	0	111.7	V89 M93 D327 I329 L334 V335 I356 A376 L377 S380 I381	V89-Y331 HydrophobicContact CG1-CD2 3.97Å; M93-Y331 HydrophobicContact CE-CD2 4.48Å; M93-Y331 HydrophobicContact CE-CG 4.27Å; D327-Y331 HydrophobicContact CB-CD2 4.39Å; D327-Y331 HydrophobicContact CB-CE2 3.85Å; D327-Y331 VanDerWaalsContact O-CB 3.28Å; D327-Y331 WeakPolarHBondContact O-CB 3.45Å; D327-Y331 WeakPolarHBondContact O-CD2 3.36Å; D327-Y331 PolarHBondContact O-N 3.42Å; I329-Y331 PolarHBondContact O-N 3.5Å; Y331-L334 PolarHBondContact O-N 3.44Å; Y331-V335 WeakPolarHBondContact O-CG2 3.16Å; Y331-V335 PolarHBondContact O-N 3.27Å; Y331-I356 HydrophobicContact CD1-CG2 3.83Å; Y331-I356 HydrophobicContact CD2-CG2 3.89Å; Y331-I356 HydrophobicContact CE1-CG2 4.19Å; Y331-I356 HydrophobicContact CE2-CG2 4.24Å; Y331-I356 HydrophobicContact CG-CG2 3.69Å; Y331-A376 VanDerWaalsContact OH-C 3.28Å; Y331-A376 PolarHBondContact OH-O 3.5Å; Y331-L377 HydrophobicContact CD1-CD2 4.29Å; Y331-L377 HydrophobicContact CE1-CD2 3.74Å; Y331-S380 WeakPolarHBondContact CE1-OG 3.08Å; Y331-S380 PolarHBondContact OH-OG 3.11Å; Y331-I381 HydrophobicContact CD1-CD1 3.92Å; Y331-I381 HydrophobicContact CD1-CG1 4.48Å; Y331-I381 HydrophobicContact CE1-CD1 4.25Å; Y331-I381 HydrophobicContact CE1-CG1 4.32Å
332	S	97	Very high	91.8	Very high	1 Å²	1	17.9 Å²	17.9	1%	0.007	11%	0.11	C	C	.	.	H	α-helix	trans	-70.7	-32.4	178.8	-54.5	0	0	0	0	112.3	C92 F328 I329 F330 G336	C92-S332 PolarHBondContact SG-OG 2.98Å; F328-S332 VanDerWaalsContact O-CB 3.25Å; F328-S332 WeakPolarHBondContact O-CB 3.29Å; F328-S332 PolarHBondContact O-N 2.99Å; F328-S332 PolarHBondContact O-OG 2.92Å; I329-S332 PolarHBondContact O-N 3.3Å; F330-S332 VanDerWaalsContact C-N 3.34Å; S332-G336 WeakPolarHBondContact O-CA 3.5Å; S332-G336 PolarHBondContact O-N 3.46Å
333	V	96.6	Very high	91.5	Very high	4 Å²	4	16.6 Å²	16.6	2%	0.024	12%	0.115	C	C	.	.	H	α-helix	trans	-62.8	-47	171.1	171.3	0	0	0	0	110.5	A234 F237 I238 L250 I329 F330 G336 K337	A234-V333 HydrophobicContact CB-CG2 3.92Å; F237-V333 HydrophobicContact CB-CG2 3.71Å; F237-V333 HydrophobicContact CD2-CG2 4.35Å; F237-V333 HydrophobicContact CG-CG2 4.42Å; I238-V333 HydrophobicContact CG1-CG1 4.38Å; I238-V333 HydrophobicContact CG1-CG2 4.41Å; L250-V333 HydrophobicContact CD1-CG1 4.38Å; L250-V333 HydrophobicContact CD2-CG1 4.27Å; I329-V333 HydrophobicContact CG2-CG2 4.31Å; I329-V333 VanDerWaalsContact O-CG2 3.25Å; I329-V333 WeakPolarHBondContact O-CG2 3.23Å; I329-V333 PolarHBondContact O-N 2.97Å; F330-V333 PolarHBondContact O-N 2.83Å; V333-G336 PolarHBondContact O-N 2.97Å; V333-K337 HydrophobicContact CG1-CG 4.23Å; V333-K337 WeakPolarHBondContact O-CB 3.45Å; V333-K337 VanDerWaalsContact O-CG 3.25Å; V333-K337 WeakPolarHBondContact O-CG 3.49Å; V333-K337 PolarHBondContact O-N 3.25Å
334	L	96.7	Very high	90.8	Very high	0 Å²	0	16.2 Å²	16.2	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-59.7	-53.8	179	-169.2	159.9	0	0	0	111.3	W247 L250 F330 Y331 G336 K337 A338 C352 I356 I381	W247-L334 HydrophobicContact CZ3-CG 4.16Å; L250-L334 HydrophobicContact CD1-CB 4.02Å; L250-L334 HydrophobicContact CD1-CG 4.27Å; F330-L334 PolarHBondContact O-N 3.01Å; Y331-L334 PolarHBondContact O-N 3.44Å; L334-G336 VanDerWaalsContact C-N 3.32Å; L334-G336 PolarHBondContact O-N 2.88Å; L334-K337 PolarHBondContact O-N 3.38Å; L334-A338 PolarHBondContact O-N 2.94Å; L334-C352 HydrophobicContact CD2-CB 3.7Å; L334-I356 HydrophobicContact CB-CD1 4.43Å; L334-I356 HydrophobicContact CD2-CD1 4.17Å; L334-I381 HydrophobicContact CB-CD1 4.43Å; L334-I381 HydrophobicContact CD1-CD1 3.69Å; L334-I381 HydrophobicContact CD1-CG2 4.31Å
335	V	96.6	Very high	90.2	Very high	3 Å²	3	19.8 Å²	19.8	2%	0.018	13%	0.128	C	C	.	.	H	α-helix	trans	-64.4	-39	-179.5	-179.5	0	0	0	0	111	M93 V97 Y331 A338 S339 T349 C352 I356	M93-V335 HydrophobicContact CE-CG2 4.2Å; M93-V335 HydrophobicContact CG-CG2 4.28Å; M93-V335 HydrophobicContact SD-CG2 4.22Å; V97-V335 HydrophobicContact CG2-CG1 3.52Å; Y331-V335 WeakPolarHBondContact O-CG2 3.16Å; Y331-V335 PolarHBondContact O-N 3.27Å; V335-A338 WeakPolarHBondContact O-CB 3.47Å; V335-A338 PolarHBondContact O-N 3.49Å; V335-S339 WeakPolarHBondContact O-CB 3.47Å; V335-S339 PolarHBondContact O-N 3.29Å; V335-T349 HydrophobicContact CG1-CG2 3.66Å; V335-C352 HydrophobicContact CG2-CB 4.49Å; V335-I356 HydrophobicContact CG2-CD1 3.5Å
336	G	95.6	Very high	90.5	Very high	0 Å²	0	25.5 Å²	25.5	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-68.5	-39.5	178.6	0	0	0	0	0	113.5	I100 S332 V333 L334 S339 A340	I100-G336 WeakPolarHBondContact CD1-O 3.26Å; S332-G336 WeakPolarHBondContact O-CA 3.5Å; S332-G336 PolarHBondContact O-N 3.46Å; V333-G336 PolarHBondContact O-N 2.97Å; L334-G336 VanDerWaalsContact C-N 3.32Å; L334-G336 PolarHBondContact O-N 2.88Å; G336-S339 PolarHBondContact O-N 2.97Å; G336-A340 VanDerWaalsContact O-CB 3.31Å; G336-A340 WeakPolarHBondContact O-CB 3.34Å; G336-A340 PolarHBondContact O-N 2.88Å
337	K	94.6	Very high	90.6	Very high	11 Å²	11	28.2 Å²	28.2	5%	0.048	16%	0.156	C	C	.	.	H	α-helix	trans	-64.8	-41.2	172.6	-69.2	-65.4	-68.6	-170.6	0	111.2	I238 L241 A246 W247 V333 L334 S339 A340 T341	I238-K337 HydrophobicContact CB-CD 4.45Å; I238-K337 HydrophobicContact CG1-CD 4.24Å; I238-K337 HydrophobicContact CG1-CG 4.32Å; I238-K337 HydrophobicContact CG2-CD 4.16Å; L241-K337 PolarHBondContact O-NZ 3.25Å; A246-K337 HydrophobicContact CB-CD 4.36Å; W247-K337 HydrophobicContact CH2-CB 4.18Å; W247-K337 HydrophobicContact CZ2-CB 3.97Å; V333-K337 HydrophobicContact CG1-CG 4.23Å; V333-K337 WeakPolarHBondContact O-CB 3.45Å; V333-K337 VanDerWaalsContact O-CG 3.25Å; V333-K337 WeakPolarHBondContact O-CG 3.49Å; V333-K337 PolarHBondContact O-N 3.25Å; L334-K337 PolarHBondContact O-N 3.38Å; K337-S339 VanDerWaalsContact C-N 3.34Å; K337-S339 PolarHBondContact O-N 3.48Å; K337-A340 PolarHBondContact O-N 3.38Å; K337-T341 PolarHBondContact O-N 3.39Å; K337-T341 PolarHBondContact O-OG1 2.9Å
338	A	95.1	Very high	90.8	Very high	0 Å²	0	27.4 Å²	27.4	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-57.8	-47.5	172.8	0	0	0	0	0	111.2	L334 V335 A340 A342 T348 Y388	L334-A338 PolarHBondContact O-N 2.94Å; V335-A338 WeakPolarHBondContact O-CB 3.47Å; V335-A338 PolarHBondContact O-N 3.49Å; A338-A340 VanDerWaalsContact C-N 3.31Å; A338-A340 PolarHBondContact O-N 2.96Å; A338-A342 WeakPolarHBondContact O-CB 3.28Å; A338-A342 PolarHBondContact O-N 2.9Å; A338-T348 HydrophobicContact CB-CG2 4.34Å; A338-Y388 HydrophobicContact CB-CD2 3.75Å; A338-Y388 HydrophobicContact CB-CE2 3.98Å
339	S	94.4	Very high	90.8	Very high	3 Å²	3	27.6 Å²	27.6	2%	0.021	15%	0.153	C	C	.	.	H	α-helix	trans	-65.7	-28.5	178	177.7	0	0	0	0	114.7	K101 V335 G336 K337 T349	K101-S339 WeakPolarHBondContact CE-O 3.27Å; K101-S339 VanDerWaalsContact CE-OG 3.26Å; K101-S339 WeakPolarHBondContact CE-OG 3.34Å; K101-S339 PolarHBondContact NZ-O 2.71Å; V335-S339 WeakPolarHBondContact O-CB 3.47Å; V335-S339 PolarHBondContact O-N 3.29Å; G336-S339 PolarHBondContact O-N 2.97Å; K337-S339 VanDerWaalsContact C-N 3.34Å; K337-S339 PolarHBondContact O-N 3.48Å; S339-T349 VanDerWaalsContact CA-OG1 3.27Å; S339-T349 WeakPolarHBondContact CA-OG1 3.36Å; S339-T349 PolarHBondContact N-OG1 2.96Å
340	A	91.9	Very high	90.8	Very high	33 Å²	33	31 Å²	31	27%	0.273	17%	0.17	S	C	.	.	H	α-helix	trans	-86.3	-31.3	-175.7	0	0	0	0	0	113.6	I100 T107 G336 K337 A338	I100-A340 HydrophobicContact CG2-CB 3.8Å; T107-A340 HydrophobicContact CG2-CB 4.13Å; G336-A340 VanDerWaalsContact O-CB 3.31Å; G336-A340 WeakPolarHBondContact O-CB 3.34Å; G336-A340 PolarHBondContact O-N 2.88Å; K337-A340 PolarHBondContact O-N 3.38Å; A338-A340 VanDerWaalsContact C-N 3.31Å; A338-A340 PolarHBondContact O-N 2.96Å
341	T	85.7	Confident	90.8	Very high	44 Å²	44	30.8 Å²	30.8	27%	0.27	17%	0.173	S	C	.	.	H	α-helix	trans	-127.7	-15.3	-166	57.5	0	0	0	0	115	E243 K337	E243-T341 HydrophobicContact CG-CG2 4.06Å; K337-T341 PolarHBondContact O-N 3.39Å; K337-T341 PolarHBondContact O-OG1 2.9Å
342	A	81.6	Confident	90.8	Very high	11 Å²	11	30.8 Å²	30.8	9%	0.091	17%	0.173	C	C	.	.			trans	-64	143.7	176.5	0	0	0	0	0	110.4	A338 G344 T348 Y388 D392	A338-A342 WeakPolarHBondContact O-CB 3.28Å; A338-A342 PolarHBondContact O-N 2.9Å; A342-G344 PolarHBondContact O-N 2.82Å; A342-T348 HydrophobicContact CB-CG2 3.83Å; A342-Y388 HydrophobicContact CB-CE2 4.24Å; A342-D392 WeakPolarHBondContact CA-OD1 3.45Å; A342-D392 WeakPolarHBondContact CB-OD1 3.31Å
343	S	74.1	Confident	90.8	Very high	89 Å²	89	33.3 Å²	33.3	62%	0.622	18%	0.184	S	C	*	.	S	Bend	trans	-71	-27.5	173.6	-58.8	0	0	0	0	110	D345 D392 Q396	S343-D345 PolarHBondContact O-N 2.75Å; S343-D392 PolarHBondContact N-OD1 3.49Å; S343-Q396 VanDerWaalsContact C-CD 3.47Å; S343-Q396 VanDerWaalsContact C-OE1 3.24Å; S343-Q396 VanDerWaalsContact CB-OE1 3.26Å; S343-Q396 PolarHBondContact O-NE2 3.1Å; S343-Q396 VanDerWaalsContact O-NE2 3.11Å
344	G	67.7	Low	90.8	Very high	6 Å²	6	36.3 Å²	36.3	6%	0.062	20%	0.202	C	C	.	.	S	Bend	trans	-94.5	87	-177.1	0	0	0	0	0	110.7	A342 W346 T348 Q396	A342-G344 PolarHBondContact O-N 2.82Å; G344-W346 VanDerWaalsContact C-N 3.32Å; G344-W346 PolarHBondContact O-N 3.05Å; G344-T348 PolarHBondContact O-N 2.93Å; G344-T348 PolarHBondContact O-OG1 3.31Å; G344-Q396 VanDerWaalsContact CA-CD 3.42Å; G344-Q396 VanDerWaalsContact CA-OE1 3.25Å
345	D	74.4	Confident	90.8	Very high	103 Å²	103	36.4 Å²	36.4	55%	0.551	20%	0.203	S	C	*	.	T	Hydrogen-bonded Turn	trans	-40	-49.7	-163.5	-99.3	-42.6	0	0	0	116.3	K101 S343 T349	K101-D345 PolarHBondContact NZ-O 3.4Å; K101-D345 IonicContact NZ-OD1 2.71Å; K101-D345 PolarHBondContact NZ-OD1 3.48Å; S343-D345 PolarHBondContact O-N 2.75Å; D345-T349 PolarHBondContact O-OG1 2.97Å
346	W	92.4	Very high	90.8	Very high	133 Å²	133	36.2 Å²	36.2	50%	0.504	20%	0.202	S	C	.	.	T	Hydrogen-bonded Turn	trans	-118	-29.7	-176	-70.6	101.7	0	0	0	113.8	V97 K101 G344 T348 T349 I350	V97-W346 HydrophobicContact CG1-CH2 4.01Å; V97-W346 HydrophobicContact CG1-CZ3 3.74Å; K101-W346 HydrophobicContact CG-CH2 4.12Å; K101-W346 HydrophobicContact CG-CZ2 4.12Å; G344-W346 VanDerWaalsContact C-N 3.32Å; G344-W346 PolarHBondContact O-N 3.05Å; W346-T348 PolarHBondContact O-N 3.29Å; W346-T349 PolarHBondContact O-N 2.87Å; W346-I350 HydrophobicContact CB-CD1 4.37Å; W346-I350 WeakPolarHBondContact O-CB 3.13Å; W346-I350 VanDerWaalsContact O-CG1 3.29Å; W346-I350 WeakPolarHBondContact O-CG1 3.44Å; W346-I350 PolarHBondContact O-N 3.5Å
347	N	93.9	Very high	90.8	Very high	87 Å²	87	37.4 Å²	37.4	47%	0.465	21%	0.208	S	C	.	.	H	α-helix	trans	-60.2	-48	-177.7	-68.5	-14.6	0	0	0	111.2	T349 I350 A351 T391	N347-T349 PolarHBondContact O-N 3.26Å; N347-I350 PolarHBondContact O-N 3.41Å; N347-A351 VanDerWaalsContact O-CB 3.28Å; N347-A351 WeakPolarHBondContact O-CB 3.31Å; N347-A351 PolarHBondContact O-N 2.86Å; N347-T391 HydrophobicContact CB-CG2 4.4Å
348	T	94.7	Very high	90.8	Very high	0 Å²	0	41.1 Å²	41.1	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-65.8	-40.9	179.9	-51.4	0	0	0	0	111.3	A338 A342 G344 W346 A351 C352 Y388 D392	A338-T348 HydrophobicContact CB-CG2 4.34Å; A342-T348 HydrophobicContact CB-CG2 3.83Å; G344-T348 PolarHBondContact O-N 2.93Å; G344-T348 PolarHBondContact O-OG1 3.31Å; W346-T348 PolarHBondContact O-N 3.29Å; T348-A351 PolarHBondContact O-N 3.08Å; T348-C352 WeakPolarHBondContact O-CB 3.44Å; T348-C352 PolarHBondContact O-N 3.09Å; T348-C352 PolarHBondContact O-SG 3.47Å; T348-Y388 HydrophobicContact CG2-CD2 3.45Å; T348-Y388 VanDerWaalsContact CG2-CD2 3.45Å; T348-Y388 HydrophobicContact CG2-CE2 3.85Å; T348-Y388 HydrophobicContact CG2-CG 4.39Å; T348-D392 HydrophobicContact CG2-CB 4.34Å
349	T	95.7	Very high	90.8	Very high	6 Å²	6	41.1 Å²	41.1	4%	0.037	23%	0.228	C	C	.	.	H	α-helix	trans	-63.4	-45.4	178.2	-54.4	0	0	0	0	111.9	V97 V335 S339 D345 W346 N347 C352 F353	V97-T349 HydrophobicContact CG1-CG2 4.29Å; V97-T349 HydrophobicContact CG2-CG2 3.97Å; V335-T349 HydrophobicContact CG1-CG2 3.66Å; S339-T349 VanDerWaalsContact CA-OG1 3.27Å; S339-T349 WeakPolarHBondContact CA-OG1 3.36Å; S339-T349 PolarHBondContact N-OG1 2.96Å; D345-T349 PolarHBondContact O-OG1 2.97Å; W346-T349 PolarHBondContact O-N 2.87Å; N347-T349 PolarHBondContact O-N 3.26Å; T349-C352 PolarHBondContact O-N 3.34Å; T349-F353 WeakPolarHBondContact O-CB 3.28Å; T349-F353 PolarHBondContact O-N 2.93Å
350	I	95.9	Very high	90.7	Very high	93 Å²	93	41 Å²	41	48%	0.477	23%	0.227	S	C	.	.	H	α-helix	trans	-69.2	-40	178.7	-65.6	167.9	0	0	0	110.7	W346 N347 C352 F353 V354	W346-I350 HydrophobicContact CB-CD1 4.37Å; W346-I350 WeakPolarHBondContact O-CB 3.13Å; W346-I350 VanDerWaalsContact O-CG1 3.29Å; W346-I350 WeakPolarHBondContact O-CG1 3.44Å; W346-I350 PolarHBondContact O-N 3.5Å; N347-I350 PolarHBondContact O-N 3.41Å; I350-C352 PolarHBondContact O-N 3.36Å; I350-F353 WeakPolarHBondContact O-CB 3.34Å; I350-F353 PolarHBondContact O-N 2.99Å; I350-V354 HydrophobicContact CG2-CG2 4.43Å; I350-V354 WeakPolarHBondContact O-CG2 3.23Å; I350-V354 PolarHBondContact O-N 3.36Å
351	A	96	Very high	90.7	Very high	20 Å²	20	41.7 Å²	41.7	17%	0.165	23%	0.229	C	C	.	.	H	α-helix	trans	-59.3	-46.8	174.8	0	0	0	0	0	111.5	N347 T348 F353 V354 A355 F387 T391	N347-A351 VanDerWaalsContact O-CB 3.28Å; N347-A351 WeakPolarHBondContact O-CB 3.31Å; N347-A351 PolarHBondContact O-N 2.86Å; T348-A351 PolarHBondContact O-N 3.08Å; A351-F353 PolarHBondContact O-N 3.48Å; A351-V354 PolarHBondContact O-N 3.1Å; A351-A355 WeakPolarHBondContact O-CB 3.49Å; A351-A355 PolarHBondContact O-N 2.85Å; A351-F387 HydrophobicContact CB-CD2 4.47Å; A351-T391 HydrophobicContact CB-CG2 4.23Å; A351-T391 WeakPolarHBondContact CB-OG1 3.43Å
352	C	95.6	Very high	91	Very high	0 Å²	0	42.8 Å²	42.8	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-61.7	-41.2	174.5	-70.7	0	0	0	0	112.6	L334 V335 T348 T349 I350 A355 I356	L334-C352 HydrophobicContact CD2-CB 3.7Å; V335-C352 HydrophobicContact CG2-CB 4.49Å; T348-C352 WeakPolarHBondContact O-CB 3.44Å; T348-C352 PolarHBondContact O-N 3.09Å; T348-C352 PolarHBondContact O-SG 3.47Å; T349-C352 PolarHBondContact O-N 3.34Å; I350-C352 PolarHBondContact O-N 3.36Å; C352-A355 PolarHBondContact O-N 2.93Å; C352-I356 WeakPolarHBondContact O-CG1 3.49Å; C352-I356 PolarHBondContact O-N 2.84Å
353	F	96.4	Very high	91.5	Very high	53 Å²	53	42.7 Å²	42.7	23%	0.232	23%	0.231	C	C	.	.	H	α-helix	trans	-58.7	-50.7	176	174.4	-99.6	0	0	0	111.6	T90 M93 T349 I350 A351 A355 I356 L357	T90-F353 HydrophobicContact CG2-CE2 3.81Å; T90-F353 HydrophobicContact CG2-CZ 3.67Å; M93-F353 HydrophobicContact SD-CD2 3.41Å; M93-F353 WeakPolarHBondContact SD-CD2 3.39Å; M93-F353 HydrophobicContact SD-CE2 3.65Å; T349-F353 WeakPolarHBondContact O-CB 3.28Å; T349-F353 PolarHBondContact O-N 2.93Å; I350-F353 WeakPolarHBondContact O-CB 3.34Å; I350-F353 PolarHBondContact O-N 2.99Å; A351-F353 PolarHBondContact O-N 3.48Å; F353-A355 PolarHBondContact O-N 3.34Å; F353-I356 PolarHBondContact O-N 2.96Å; F353-L357 HydrophobicContact CD1-CD1 4.15Å; F353-L357 HydrophobicContact CE1-CD1 3.44Å; F353-L357 VanDerWaalsContact CE1-CD1 3.44Å; F353-L357 HydrophobicContact CE1-CG 4.28Å; F353-L357 HydrophobicContact CE2-CD1 4.18Å; F353-L357 HydrophobicContact CE2-CG 4.4Å; F353-L357 HydrophobicContact CZ-CD1 3.45Å; F353-L357 VanDerWaalsContact CZ-CD1 3.45Å; F353-L357 HydrophobicContact CZ-CG 4.14Å; F353-L357 WeakPolarHBondContact O-CG 3.43Å; F353-L357 PolarHBondContact O-N 3.23Å; F353-L357 VanDerWaalsContact O-N 3.09Å
354	V	96.9	Very high	92.1	Very high	67 Å²	67	39.6 Å²	39.6	41%	0.406	21%	0.207	S	C	.	.	H	α-helix	trans	-62	-43.5	177.7	174.6	0	0	0	0	110.7	I350 A351 I356 L357 I358	I350-V354 HydrophobicContact CG2-CG2 4.43Å; I350-V354 WeakPolarHBondContact O-CG2 3.23Å; I350-V354 PolarHBondContact O-N 3.36Å; A351-V354 PolarHBondContact O-N 3.1Å; V354-I356 VanDerWaalsContact C-N 3.33Å; V354-I356 PolarHBondContact O-N 3.32Å; V354-L357 PolarHBondContact O-N 3.42Å; V354-I358 HydrophobicContact CG1-CG1 4.17Å; V354-I358 VanDerWaalsContact O-CG1 3.32Å; V354-I358 WeakPolarHBondContact O-CG1 3.23Å; V354-I358 PolarHBondContact O-N 3.35Å
355	A	97.1	Very high	93.1	Very high	2 Å²	2	44.1 Å²	44.1	2%	0.017	23%	0.23	C	C	.	.	H	α-helix	trans	-57.6	-43.6	177.8	0	0	0	0	0	112.8	A351 C352 F353 G359 F383 F387	A351-A355 WeakPolarHBondContact O-CB 3.49Å; A351-A355 PolarHBondContact O-N 2.85Å; C352-A355 PolarHBondContact O-N 2.93Å; F353-A355 PolarHBondContact O-N 3.34Å; A355-G359 PolarHBondContact O-N 2.91Å; A355-F383 HydrophobicContact CB-CB 3.97Å; A355-F387 HydrophobicContact CB-CB 4.11Å; A355-F387 HydrophobicContact CB-CD2 3.69Å; A355-F387 HydrophobicContact CB-CE2 4.29Å; A355-F387 HydrophobicContact CB-CG 3.95Å
356	I	96.3	Very high	93.8	Very high	0 Å²	0	42 Å²	42	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-67.3	-43.8	178.2	-67.5	165.3	0	0	0	111	M93 Y331 L334 V335 C352 F353 V354 G359 L360	M93-I356 HydrophobicContact CE-CB 4Å; M93-I356 HydrophobicContact CE-CD1 3.78Å; M93-I356 HydrophobicContact CE-CG2 3.5Å; Y331-I356 HydrophobicContact CD1-CG2 3.83Å; Y331-I356 HydrophobicContact CD2-CG2 3.89Å; Y331-I356 HydrophobicContact CE1-CG2 4.19Å; Y331-I356 HydrophobicContact CE2-CG2 4.24Å; Y331-I356 HydrophobicContact CG-CG2 3.69Å; L334-I356 HydrophobicContact CB-CD1 4.43Å; L334-I356 HydrophobicContact CD2-CD1 4.17Å; V335-I356 HydrophobicContact CG2-CD1 3.5Å; C352-I356 WeakPolarHBondContact O-CG1 3.49Å; C352-I356 PolarHBondContact O-N 2.84Å; F353-I356 PolarHBondContact O-N 2.96Å; V354-I356 VanDerWaalsContact C-N 3.33Å; V354-I356 PolarHBondContact O-N 3.32Å; I356-G359 PolarHBondContact O-N 3.23Å; I356-L360 WeakPolarHBondContact O-CB 3.3Å; I356-L360 PolarHBondContact O-N 3.42Å
357	L	95.4	Very high	93.5	Very high	25 Å²	25	39.3 Å²	39.3	13%	0.131	21%	0.213	C	C	.	.	H	α-helix	trans	-62.5	-43.8	177.9	-69.5	-172.1	0	0	0	111.8	F86 F353 V354 L360 C361	F86-L357 HydrophobicContact CD1-CD2 4.26Å; F86-L357 HydrophobicContact CD2-CD2 4.3Å; F86-L357 HydrophobicContact CE1-CD2 4.28Å; F86-L357 HydrophobicContact CE2-CB 4.21Å; F86-L357 HydrophobicContact CE2-CD1 4.44Å; F86-L357 HydrophobicContact CE2-CD2 4.34Å; F86-L357 HydrophobicContact CG-CD2 4.22Å; F86-L357 HydrophobicContact CZ-CB 4.01Å; F86-L357 HydrophobicContact CZ-CD2 4.27Å; F86-L357 VanDerWaalsContact CZ-O 3.31Å; F86-L357 WeakPolarHBondContact CZ-O 3.31Å; F353-L357 HydrophobicContact CD1-CD1 4.15Å; F353-L357 HydrophobicContact CE1-CD1 3.44Å; F353-L357 VanDerWaalsContact CE1-CD1 3.44Å; F353-L357 HydrophobicContact CE1-CG 4.28Å; F353-L357 HydrophobicContact CE2-CD1 4.18Å; F353-L357 HydrophobicContact CE2-CG 4.4Å; F353-L357 HydrophobicContact CZ-CD1 3.45Å; F353-L357 VanDerWaalsContact CZ-CD1 3.45Å; F353-L357 HydrophobicContact CZ-CG 4.14Å; F353-L357 WeakPolarHBondContact O-CG 3.43Å; F353-L357 PolarHBondContact O-N 3.23Å; F353-L357 VanDerWaalsContact O-N 3.09Å; V354-L357 PolarHBondContact O-N 3.42Å; L357-L360 PolarHBondContact O-N 3.31Å; L357-C361 PolarHBondContact O-N 3.33Å
358	I	95.4	Very high	93	Very high	89 Å²	89	38.2 Å²	38.2	46%	0.456	22%	0.216	S	C	.	.	H	α-helix	trans	-63	-43.3	175.2	-66	-62.6	0	0	0	110.7	V354 L360 C361 L362 F383	V354-I358 HydrophobicContact CG1-CG1 4.17Å; V354-I358 VanDerWaalsContact O-CG1 3.32Å; V354-I358 WeakPolarHBondContact O-CG1 3.23Å; V354-I358 PolarHBondContact O-N 3.35Å; I358-L360 VanDerWaalsContact C-N 3.31Å; I358-L360 PolarHBondContact O-N 3.4Å; I358-C361 WeakPolarHBondContact O-CB 3.32Å; I358-C361 PolarHBondContact O-N 3.41Å; I358-L362 WeakPolarHBondContact O-CG 3.44Å; I358-L362 PolarHBondContact O-N 3.25Å; I358-F383 HydrophobicContact CG2-CE2 4.39Å
359	G	94.9	Very high	92.7	Very high	0 Å²	0	43.4 Å²	43.4	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-60.1	-39.7	174.6	0	0	0	0	0	112.9	A355 I356 L362 T363	A355-G359 PolarHBondContact O-N 2.91Å; I356-G359 PolarHBondContact O-N 3.23Å; G359-L362 PolarHBondContact O-N 2.97Å; G359-T363 WeakPolarHBondContact O-CG2 3.42Å; G359-T363 PolarHBondContact O-N 3.39Å; G359-T363 PolarHBondContact O-OG1 2.76Å
360	L	92.3	Very high	92.2	Very high	1 Å²	1	49 Å²	49	1%	0.005	27%	0.267	C	S	.	.	H	α-helix	trans	-67.3	-37.6	174.9	-173.9	64.1	0	0	0	112.1	L85 F86 V89 I356 L357 I358 T363 L364	L85-L360 HydrophobicContact CB-CD2 4.33Å; F86-L360 HydrophobicContact CD1-CD2 3.72Å; F86-L360 HydrophobicContact CD1-CG 4.41Å; F86-L360 HydrophobicContact CE1-CB 4.08Å; F86-L360 HydrophobicContact CE1-CD2 3.72Å; F86-L360 HydrophobicContact CE1-CG 3.96Å; V89-L360 HydrophobicContact CG2-CD2 4.38Å; I356-L360 WeakPolarHBondContact O-CB 3.3Å; I356-L360 PolarHBondContact O-N 3.42Å; L357-L360 PolarHBondContact O-N 3.31Å; I358-L360 VanDerWaalsContact C-N 3.31Å; I358-L360 PolarHBondContact O-N 3.4Å; L360-T363 WeakPolarHBondContact CA-OG1 3.49Å; L360-T363 PolarHBondContact O-OG1 3Å; L360-L364 HydrophobicContact CG-CD1 4.36Å; L360-L364 WeakPolarHBondContact O-CB 3.36Å; L360-L364 VanDerWaalsContact O-CG 3.28Å; L360-L364 WeakPolarHBondContact O-CG 3.45Å; L360-L364 PolarHBondContact O-N 2.95Å
361	C	92.2	Very high	91.6	Very high	46 Å²	46	53.4 Å²	53.4	31%	0.311	28%	0.282	S	S	.	.	H	α-helix	trans	-59.4	-47.6	170.7	-92.4	0	0	0	0	111.5	F86 L357 I358 L364 L365	F86-C361 HydrophobicContact CZ-CB 4.42Å; F86-C361 WeakPolarHBondContact CZ-SG 3.27Å; L357-C361 PolarHBondContact O-N 3.33Å; I358-C361 WeakPolarHBondContact O-CB 3.32Å; I358-C361 PolarHBondContact O-N 3.41Å; C361-L364 PolarHBondContact O-N 2.95Å; C361-L365 WeakPolarHBondContact O-CB 3.34Å; C361-L365 PolarHBondContact O-N 3.31Å
362	L	92.8	Very high	90.8	Very high	67 Å²	67	59.8 Å²	59.8	35%	0.351	31%	0.307	S	S	.	.	H	α-helix	trans	-65.8	-40.3	179.8	-67.3	-171.9	0	0	0	112.3	I358 G359 L364 L365 L366 I379 F383	I358-L362 WeakPolarHBondContact O-CG 3.44Å; I358-L362 PolarHBondContact O-N 3.25Å; G359-L362 PolarHBondContact O-N 2.97Å; L362-L364 VanDerWaalsContact C-N 3.34Å; L362-L364 PolarHBondContact O-N 2.62Å; L362-L365 PolarHBondContact O-N 3.48Å; L362-L366 WeakPolarHBondContact O-CB 3.26Å; L362-L366 VanDerWaalsContact O-CG 3.25Å; L362-L366 WeakPolarHBondContact O-CG 3.2Å; L362-L366 PolarHBondContact O-N 3Å; L362-I379 HydrophobicContact CB-CG2 4.38Å; L362-I379 HydrophobicContact CD1-CG2 4.39Å; L362-F383 HydrophobicContact CD1-CE2 3.6Å; L362-F383 HydrophobicContact CD1-CZ 3.92Å
363	T	91.1	Very high	90	Very high	9 Å²	9	63 Å²	63	6%	0.055	33%	0.333	C	S	.	.	H	α-helix	trans	-64.4	-39.8	177	54.5	0	0	0	0	111.6	G359 L360 L366 L367 I379	G359-T363 WeakPolarHBondContact O-CG2 3.42Å; G359-T363 PolarHBondContact O-N 3.39Å; G359-T363 PolarHBondContact O-OG1 2.76Å; L360-T363 WeakPolarHBondContact CA-OG1 3.49Å; L360-T363 PolarHBondContact O-OG1 3Å; T363-L366 PolarHBondContact O-N 3.43Å; T363-L367 WeakPolarHBondContact O-CB 3.39Å; T363-L367 PolarHBondContact O-N 3.48Å; T363-I379 HydrophobicContact CG2-CB 3.98Å; T363-I379 HydrophobicContact CG2-CD1 3.91Å; T363-I379 HydrophobicContact CG2-CG1 4.27Å
364	L	87	Confident	89.6	Confident	25 Å²	25	62.9 Å²	62.9	13%	0.131	34%	0.335	C	S	.	.	H	α-helix	trans	-67.6	-38.6	174.6	-69.6	173.4	0	0	0	112.7	V82 L85 L360 C361 L362 L367 A368	V82-L364 HydrophobicContact CB-CD1 4.2Å; V82-L364 HydrophobicContact CG1-CD1 4.38Å; V82-L364 HydrophobicContact CG2-CB 4.38Å; V82-L364 HydrophobicContact CG2-CD1 3.73Å; L85-L364 HydrophobicContact CD1-CD1 3.83Å; L85-L364 HydrophobicContact CD1-CD2 3.73Å; L85-L364 HydrophobicContact CD1-CG 4.31Å; L360-L364 HydrophobicContact CG-CD1 4.36Å; L360-L364 WeakPolarHBondContact O-CB 3.36Å; L360-L364 VanDerWaalsContact O-CG 3.28Å; L360-L364 WeakPolarHBondContact O-CG 3.45Å; L360-L364 PolarHBondContact O-N 2.95Å; C361-L364 PolarHBondContact O-N 2.95Å; L362-L364 VanDerWaalsContact C-N 3.34Å; L362-L364 PolarHBondContact O-N 2.62Å; L364-L367 PolarHBondContact O-N 3.05Å; L364-A368 PolarHBondContact O-N 3.31Å
365	L	89.3	Confident	89.2	Confident	101 Å²	101	60.3 Å²	60.3	53%	0.529	32%	0.319	S	S	.	.	H	α-helix	trans	-61.1	-46.6	173.6	-177	68.4	0	0	0	111.1	C361 L362 L367 A368 I369	C361-L365 WeakPolarHBondContact O-CB 3.34Å; C361-L365 PolarHBondContact O-N 3.31Å; L362-L365 PolarHBondContact O-N 3.48Å; L365-L367 VanDerWaalsContact C-N 3.31Å; L365-L367 PolarHBondContact O-N 2.96Å; L365-A368 WeakPolarHBondContact O-CB 3.35Å; L365-A368 PolarHBondContact O-N 2.8Å; L365-I369 HydrophobicContact CG-CD1 4.21Å; L365-I369 WeakPolarHBondContact O-CG1 3.27Å; L365-I369 PolarHBondContact O-N 3.39Å; L365-I369 VanDerWaalsContact O-N 3.09Å
366	L	88.9	Confident	88.9	Confident	58 Å²	58	60.9 Å²	60.9	30%	0.304	32%	0.324	S	S	.	.	H	α-helix	trans	-64.1	-36.4	176.4	-68.2	167.1	0	0	0	111.8	L362 T363 I369 F370 L374 I379	L362-L366 WeakPolarHBondContact O-CB 3.26Å; L362-L366 VanDerWaalsContact O-CG 3.25Å; L362-L366 WeakPolarHBondContact O-CG 3.2Å; L362-L366 PolarHBondContact O-N 3Å; T363-L366 PolarHBondContact O-N 3.43Å; L366-I369 PolarHBondContact O-N 3.32Å; L366-F370 HydrophobicContact CB-CD2 4.32Å; L366-F370 HydrophobicContact CD2-CD2 4.38Å; L366-F370 HydrophobicContact CD2-CE2 3.83Å; L366-F370 WeakPolarHBondContact O-CB 3.26Å; L366-F370 VanDerWaalsContact O-CD2 3.31Å; L366-F370 WeakPolarHBondContact O-CD2 3.36Å; L366-F370 PolarHBondContact O-N 3.29Å; L366-L374 HydrophobicContact CB-CD1 3.6Å; L366-I379 HydrophobicContact CD1-CD1 3.54Å
367	L	85.6	Confident	88.6	Confident	76 Å²	76	61.2 Å²	61.2	40%	0.398	33%	0.326	S	S	.	.	H	α-helix	trans	-64.3	-42.4	175.6	-170.2	158.8	0	0	0	110.8	T363 L364 L365 I369 K371 L374	T363-L367 WeakPolarHBondContact O-CB 3.39Å; T363-L367 PolarHBondContact O-N 3.48Å; L364-L367 PolarHBondContact O-N 3.05Å; L365-L367 VanDerWaalsContact C-N 3.31Å; L365-L367 PolarHBondContact O-N 2.96Å; L367-I369 VanDerWaalsContact C-N 3.32Å; L367-I369 PolarHBondContact O-N 3.5Å; L367-K371 WeakPolarHBondContact O-CA 3.38Å; L367-K371 PolarHBondContact O-N 3.09Å; L367-L374 HydrophobicContact CB-CD1 4.34Å
368	A	83.5	Confident	88.5	Confident	65 Å²	65	60.7 Å²	60.7	54%	0.537	32%	0.323	S	S	.	.	H	α-helix	trans	-62.4	-38	176.1	0	0	0	0	0	112.5	L364 L365	L364-A368 PolarHBondContact O-N 3.31Å; L365-A368 WeakPolarHBondContact O-CB 3.35Å; L365-A368 PolarHBondContact O-N 2.8Å
369	I	87.6	Confident	88.5	Confident	109 Å²	109	58.9 Å²	58.9	56%	0.559	31%	0.314	S	S	*	.	H	α-helix	trans	-73.9	-52.7	179	-64.9	166.5	0	0	0	111.5	L365 L366 L367	L365-I369 HydrophobicContact CG-CD1 4.21Å; L365-I369 WeakPolarHBondContact O-CG1 3.27Å; L365-I369 PolarHBondContact O-N 3.39Å; L365-I369 VanDerWaalsContact O-N 3.09Å; L366-I369 PolarHBondContact O-N 3.32Å; L367-I369 VanDerWaalsContact C-N 3.32Å; L367-I369 PolarHBondContact O-N 3.5Å
370	F	87	Confident	88.5	Confident	124 Å²	124	58.9 Å²	58.9	54%	0.544	31%	0.314	S	S	.	.	H	α-helix	trans	-84.9	-17.4	-172.3	-69.3	-62.1	0	0	0	114.3	L366 K372 L374	L366-F370 HydrophobicContact CB-CD2 4.32Å; L366-F370 HydrophobicContact CD2-CD2 4.38Å; L366-F370 HydrophobicContact CD2-CE2 3.83Å; L366-F370 WeakPolarHBondContact O-CB 3.26Å; L366-F370 VanDerWaalsContact O-CD2 3.31Å; L366-F370 WeakPolarHBondContact O-CD2 3.36Å; L366-F370 PolarHBondContact O-N 3.29Å; F370-K372 WeakPolarHBondContact O-CG 3.45Å; F370-K372 PolarHBondContact O-N 3.32Å; F370-K372 VanDerWaalsContact O-N 3.09Å; F370-L374 HydrophobicContact CD2-CD1 4.43Å
371	K	83	Confident	88.7	Confident	184 Å²	184	58.9 Å²	58.9	80%	0.8	31%	0.314	S	S	*	.			trans	49.5	34.4	-178	-60.1	-177.6	178.9	174.1	0	113.5	L367	L367-K371 WeakPolarHBondContact O-CA 3.38Å; L367-K371 PolarHBondContact O-N 3.09Å
372	K	79.6	Confident	88.9	Confident	155 Å²	155	60 Å²	60	67%	0.674	32%	0.319	S	S	*	.	S	Bend	trans	-124.5	157.3	178.4	-73.8	178.6	-177.9	176.3	0	110.1	F370 L374	F370-K372 WeakPolarHBondContact O-CG 3.45Å; F370-K372 PolarHBondContact O-N 3.32Å; F370-K372 VanDerWaalsContact O-N 3.09Å; K372-L374 PolarHBondContact O-N 3.42Å
373	A	78.5	Confident	89.1	Confident	66 Å²	66	60.3 Å²	60.3	55%	0.545	32%	0.318	S	S	.	.			trans	-62.7	119.9	172	0	0	0	0	0	109.4
374	L	87.1	Confident	89.3	Confident	52 Å²	52	59.9 Å²	59.9	27%	0.272	32%	0.316	S	S	.	.			trans	-117.2	143	178.4	-67.9	179	0	0	0	110.2	L262 L366 L367 F370 K372 A376	L262-L374 HydrophobicContact CD2-CD2 4.46Å; L366-L374 HydrophobicContact CB-CD1 3.6Å; L367-L374 HydrophobicContact CB-CD1 4.34Å; F370-L374 HydrophobicContact CD2-CD1 4.43Å; K372-L374 PolarHBondContact O-N 3.42Å; L374-A376 PolarHBondContact O-N 2.88Å
375	P	89.6	Confident	89.7	Confident	13 Å²	13	59.8 Å²	59.8	8%	0.084	32%	0.315	C	S	.	.			trans	-69.2	127.3	172.7	30	-34	0	0	0	109.6	D257 L258 V261 P378	D257-P375 WeakPolarHBondContact OD2-CB 3.43Å; L258-P375 HydrophobicContact CD1-CG 4.08Å; V261-P375 HydrophobicContact CB-CB 4.33Å; V261-P375 HydrophobicContact CB-CG 4.49Å; V261-P375 HydrophobicContact CG2-CB 4.26Å; P375-P378 HydrophobicContact CB-CG 3.99Å; P375-P378 HydrophobicContact CG-CG 3.86Å
376	A	89.8	Confident	90.1	Very high	13 Å²	13	59 Å²	59	11%	0.107	31%	0.314	C	S	.	.	S	Bend	trans	-84.1	-27.9	-177.7	0	0	0	0	0	112.6	L323 Y331 L374 S380	L323-A376 HydrophobicContact CD1-CB 4.15Å; Y331-A376 VanDerWaalsContact OH-C 3.28Å; Y331-A376 PolarHBondContact OH-O 3.5Å; L374-A376 PolarHBondContact O-N 2.88Å; A376-S380 PolarHBondContact O-OG 2.72Å
377	L	90.4	Very high	90.4	Very high	8 Å²	8	60.7 Å²	60.7	4%	0.042	32%	0.319	C	S	.	.	H	α-helix	trans	-63.1	-47	-177.1	-69.7	178.5	0	0	0	116.1	D257 D327 F330 Y331 I379 S380 I381	D257-L377 HydrophobicContact CB-CD1 4.16Å; D327-L377 HydrophobicContact CB-CD2 4.42Å; D327-L377 WeakPolarHBondContact OD1-CG 3.19Å; F330-L377 HydrophobicContact CB-CD2 3.92Å; F330-L377 HydrophobicContact CD2-CD1 3.97Å; F330-L377 HydrophobicContact CD2-CD2 4.3Å; Y331-L377 HydrophobicContact CD1-CD2 4.29Å; Y331-L377 HydrophobicContact CE1-CD2 3.74Å; L377-I379 PolarHBondContact O-N 3.05Å; L377-S380 PolarHBondContact O-OG 3.37Å; L377-S380 VanDerWaalsContact O-OG 3.05Å; L377-I381 HydrophobicContact CB-CG1 4.42Å; L377-I381 HydrophobicContact CD2-CG1 4.29Å; L377-I381 WeakPolarHBondContact O-CB 3.37Å; L377-I381 WeakPolarHBondContact O-CG1 3.46Å; L377-I381 PolarHBondContact O-N 2.95Å
378	P	93.9	Very high	90.9	Very high	13 Å²	13	57.5 Å²	57.5	8%	0.084	30%	0.302	C	S	.	.	H	α-helix	trans	-63.8	-44.9	-162.8	18.9	-30.8	0	0	0	114.5	L258 P375 T382	L258-P378 HydrophobicContact CB-CB 4.48Å; L258-P378 HydrophobicContact CB-CG 4.33Å; L258-P378 HydrophobicContact CD1-CB 4.15Å; L258-P378 HydrophobicContact CD1-CG 3.79Å; P375-P378 HydrophobicContact CB-CG 3.99Å; P375-P378 HydrophobicContact CG-CG 3.86Å; P378-T382 WeakPolarHBondContact O-CB 3.44Å; P378-T382 PolarHBondContact O-N 3.27Å; P378-T382 PolarHBondContact O-OG1 2.87Å
379	I	94.9	Very high	91.4	Very high	52 Å²	52	58.6 Å²	58.6	27%	0.267	30%	0.295	S	S	.	.	H	α-helix	trans	-69.7	-47.1	-175.7	-61.9	177.1	0	0	0	110.6	L362 T363 L366 L377 T382 F383	L362-I379 HydrophobicContact CB-CG2 4.38Å; L362-I379 HydrophobicContact CD1-CG2 4.39Å; T363-I379 HydrophobicContact CG2-CB 3.98Å; T363-I379 HydrophobicContact CG2-CD1 3.91Å; T363-I379 HydrophobicContact CG2-CG1 4.27Å; L366-I379 HydrophobicContact CD1-CD1 3.54Å; L377-I379 PolarHBondContact O-N 3.05Å; I379-T382 PolarHBondContact O-N 2.68Å; I379-F383 HydrophobicContact CG2-CD2 4.28Å; I379-F383 HydrophobicContact CG2-CE2 3.89Å; I379-F383 HydrophobicContact CG2-CZ 4.19Å; I379-F383 WeakPolarHBondContact O-CG 3.31Å; I379-F383 PolarHBondContact O-N 3.35Å
380	S	95.5	Very high	91.8	Very high	0 Å²	0	55.1 Å²	55.1	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-67.5	-43.1	-179.1	50.3	0	0	0	0	112.7	Y331 A376 L377 G384	Y331-S380 WeakPolarHBondContact CE1-OG 3.08Å; Y331-S380 PolarHBondContact OH-OG 3.11Å; A376-S380 PolarHBondContact O-OG 2.72Å; L377-S380 PolarHBondContact O-OG 3.37Å; L377-S380 VanDerWaalsContact O-OG 3.05Å; S380-G384 PolarHBondContact O-N 3.4Å
381	I	95.3	Very high	92.2	Very high	0 Å²	0	49.9 Å²	49.9	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-66.7	-40.2	175.1	-64.2	-66.1	0	0	0	110.8	L250 F330 Y331 L334 L377 F383 G384 L385	L250-I381 HydrophobicContact CB-CG2 4.35Å; L250-I381 HydrophobicContact CD2-CD1 4.47Å; F330-I381 HydrophobicContact CB-CD1 4.46Å; Y331-I381 HydrophobicContact CD1-CD1 3.92Å; Y331-I381 HydrophobicContact CD1-CG1 4.48Å; Y331-I381 HydrophobicContact CE1-CD1 4.25Å; Y331-I381 HydrophobicContact CE1-CG1 4.32Å; L334-I381 HydrophobicContact CB-CD1 4.43Å; L334-I381 HydrophobicContact CD1-CD1 3.69Å; L334-I381 HydrophobicContact CD1-CG2 4.31Å; L377-I381 HydrophobicContact CB-CG1 4.42Å; L377-I381 HydrophobicContact CD2-CG1 4.29Å; L377-I381 WeakPolarHBondContact O-CB 3.37Å; L377-I381 WeakPolarHBondContact O-CG1 3.46Å; L377-I381 PolarHBondContact O-N 2.95Å; I381-F383 PolarHBondContact O-N 3.21Å; I381-G384 PolarHBondContact O-N 2.82Å; I381-L385 HydrophobicContact CG2-CD1 3.88Å; I381-L385 HydrophobicContact CG2-CG 4.09Å; I381-L385 WeakPolarHBondContact O-CB 3.27Å; I381-L385 VanDerWaalsContact O-CG 3.28Å; I381-L385 WeakPolarHBondContact O-CG 3.31Å; I381-L385 PolarHBondContact O-N 2.89Å
382	T	96.4	Very high	92.7	Very high	69 Å²	69	42 Å²	42	42%	0.423	23%	0.227	S	C	.	.	H	α-helix	trans	-59.7	-49.2	176.9	-61.1	0	0	0	0	111.1	P378 I379 G384 L385 V386	P378-T382 WeakPolarHBondContact O-CB 3.44Å; P378-T382 PolarHBondContact O-N 3.27Å; P378-T382 PolarHBondContact O-OG1 2.87Å; I379-T382 PolarHBondContact O-N 2.68Å; T382-G384 VanDerWaalsContact C-N 3.34Å; T382-G384 PolarHBondContact O-N 2.9Å; T382-L385 PolarHBondContact O-N 3.02Å; T382-V386 VanDerWaalsContact O-CG2 3.31Å; T382-V386 WeakPolarHBondContact O-CG2 3.19Å; T382-V386 PolarHBondContact O-N 2.9Å
383	F	96.7	Very high	93.4	Very high	74 Å²	74	42 Å²	42	33%	0.325	22%	0.224	S	C	.	.	H	α-helix	trans	-62.4	-41.9	175.4	-67.7	-17.9	0	0	0	112.1	A355 I358 L362 I379 I381 L385 V386 F387	A355-F383 HydrophobicContact CB-CB 3.97Å; I358-F383 HydrophobicContact CG2-CE2 4.39Å; L362-F383 HydrophobicContact CD1-CE2 3.6Å; L362-F383 HydrophobicContact CD1-CZ 3.92Å; I379-F383 HydrophobicContact CG2-CD2 4.28Å; I379-F383 HydrophobicContact CG2-CE2 3.89Å; I379-F383 HydrophobicContact CG2-CZ 4.19Å; I379-F383 WeakPolarHBondContact O-CG 3.31Å; I379-F383 PolarHBondContact O-N 3.35Å; I381-F383 PolarHBondContact O-N 3.21Å; F383-L385 PolarHBondContact O-N 3.36Å; F383-V386 PolarHBondContact O-N 3.16Å; F383-F387 WeakPolarHBondContact O-CB 3.15Å; F383-F387 PolarHBondContact O-N 3.42Å
384	G	96	Very high	94.2	Very high	0 Å²	0	44.9 Å²	44.9	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-59.4	-43.5	176.3	0	0	0	0	0	112.9	S380 I381 T382 Y388	S380-G384 PolarHBondContact O-N 3.4Å; I381-G384 PolarHBondContact O-N 2.82Å; T382-G384 VanDerWaalsContact C-N 3.34Å; T382-G384 PolarHBondContact O-N 2.9Å; G384-Y388 VanDerWaalsContact O-CB 3.23Å; G384-Y388 WeakPolarHBondContact O-CB 3.28Å; G384-Y388 PolarHBondContact O-N 3.43Å
385	L	95.8	Very high	94.5	Very high	23 Å²	23	45.3 Å²	45.3	12%	0.12	23%	0.234	C	C	.	.	H	α-helix	trans	-65.9	-47.7	176.4	-70.1	174.3	0	0	0	111.5	W247 A251 I381 T382 F383 F387 Y388 F389	W247-L385 HydrophobicContact CD2-CD2 4.48Å; W247-L385 HydrophobicContact CE3-CD2 3.36Å; W247-L385 HydrophobicContact CZ3-CD2 3.69Å; A251-L385 HydrophobicContact CB-CD1 4.07Å; I381-L385 HydrophobicContact CG2-CD1 3.88Å; I381-L385 HydrophobicContact CG2-CG 4.09Å; I381-L385 WeakPolarHBondContact O-CB 3.27Å; I381-L385 VanDerWaalsContact O-CG 3.28Å; I381-L385 WeakPolarHBondContact O-CG 3.31Å; I381-L385 PolarHBondContact O-N 2.89Å; T382-L385 PolarHBondContact O-N 3.02Å; F383-L385 PolarHBondContact O-N 3.36Å; L385-F387 VanDerWaalsContact C-N 3.33Å; L385-F387 PolarHBondContact O-N 2.95Å; L385-Y388 PolarHBondContact O-N 2.71Å; L385-F389 HydrophobicContact CD2-CE2 4.36Å; L385-F389 WeakPolarHBondContact O-CD2 3.15Å; L385-F389 PolarHBondContact O-N 3.32Å
386	V	96.8	Very high	94.7	Very high	85 Å²	85	45.5 Å²	45.5	52%	0.515	23%	0.234	S	C	.	.	H	α-helix	trans	-59.6	-46.5	178.3	172.3	0	0	0	0	110.4	T382 F383 A390	T382-V386 VanDerWaalsContact O-CG2 3.31Å; T382-V386 WeakPolarHBondContact O-CG2 3.19Å; T382-V386 PolarHBondContact O-N 2.9Å; F383-V386 PolarHBondContact O-N 3.16Å; V386-A390 WeakPolarHBondContact O-CB 3.27Å; V386-A390 PolarHBondContact O-N 3.19Å
387	F	95.8	Very high	94.8	Very high	93 Å²	93	48.1 Å²	48.1	41%	0.408	25%	0.25	S	S	.	.	H	α-helix	trans	-70.3	-34.6	-179.6	-82.4	28.8	0	0	0	111.8	A351 A355 F383 L385 T391	A351-F387 HydrophobicContact CB-CD2 4.47Å; A355-F387 HydrophobicContact CB-CB 4.11Å; A355-F387 HydrophobicContact CB-CD2 3.69Å; A355-F387 HydrophobicContact CB-CE2 4.29Å; A355-F387 HydrophobicContact CB-CG 3.95Å; F383-F387 WeakPolarHBondContact O-CB 3.15Å; F383-F387 PolarHBondContact O-N 3.42Å; L385-F387 VanDerWaalsContact C-N 3.33Å; L385-F387 PolarHBondContact O-N 2.95Å; F387-T391 WeakPolarHBondContact O-CB 3.23Å; F387-T391 PolarHBondContact O-N 2.99Å; F387-T391 PolarHBondContact O-OG1 2.91Å
388	Y	95.4	Very high	95	Very high	10 Å²	10	53.1 Å²	53.1	4%	0.039	27%	0.272	C	S	.	.	H	α-helix	trans	-58.1	-58.5	172.8	175.5	-102.6	0	0	0	111	W247 A338 A342 T348 G384 L385 A390 T391 D392	W247-Y388 HydrophobicContact CD2-CE1 4.33Å; W247-Y388 AromaticContact CE2-CE1 3.52Å; W247-Y388 AromaticContact CE2-CZ 3.84Å; W247-Y388 AromaticContact CH2-CD1 3.59Å; W247-Y388 HydrophobicContact CH2-CD1 3.59Å; W247-Y388 AromaticContact CH2-CD2 3.63Å; W247-Y388 HydrophobicContact CH2-CD2 3.63Å; W247-Y388 AromaticContact CH2-CE1 3.71Å; W247-Y388 HydrophobicContact CH2-CE1 3.71Å; W247-Y388 AromaticContact CH2-CE2 3.79Å; W247-Y388 HydrophobicContact CH2-CE2 3.79Å; W247-Y388 AromaticContact CH2-CG 3.55Å; W247-Y388 HydrophobicContact CH2-CG 3.55Å; W247-Y388 AromaticContact CH2-CZ 3.82Å; W247-Y388 AromaticContact CZ2-CD1 3.63Å; W247-Y388 HydrophobicContact CZ2-CD1 3.63Å; W247-Y388 AromaticContact CZ2-CD2 3.9Å; W247-Y388 HydrophobicContact CZ2-CD2 3.9Å; W247-Y388 AromaticContact CZ2-CE1 3.21Å; W247-Y388 HydrophobicContact CZ2-CE1 3.21Å; W247-Y388 AromaticContact CZ2-CE2 3.55Å; W247-Y388 HydrophobicContact CZ2-CE2 3.55Å; W247-Y388 AromaticContact CZ2-CG 3.95Å; W247-Y388 HydrophobicContact CZ2-CG 3.95Å; W247-Y388 AromaticContact CZ2-CZ 3.18Å; W247-Y388 HydrophobicContact CZ3-CD1 4.05Å; W247-Y388 HydrophobicContact CZ3-CE1 4.44Å; W247-Y388 HydrophobicContact CZ3-CG 4.14Å; W247-Y388 AromaticContact NE1-CE1 3.9Å; A338-Y388 HydrophobicContact CB-CD2 3.75Å; A338-Y388 HydrophobicContact CB-CE2 3.98Å; A342-Y388 HydrophobicContact CB-CE2 4.24Å; T348-Y388 HydrophobicContact CG2-CD2 3.45Å; T348-Y388 VanDerWaalsContact CG2-CD2 3.45Å; T348-Y388 HydrophobicContact CG2-CE2 3.85Å; T348-Y388 HydrophobicContact CG2-CG 4.39Å; G384-Y388 VanDerWaalsContact O-CB 3.23Å; G384-Y388 WeakPolarHBondContact O-CB 3.28Å; G384-Y388 PolarHBondContact O-N 3.43Å; L385-Y388 PolarHBondContact O-N 2.71Å; Y388-A390 PolarHBondContact O-N 2.91Å; Y388-T391 PolarHBondContact O-N 3.41Å; Y388-D392 VanDerWaalsContact O-CB 3.27Å; Y388-D392 WeakPolarHBondContact O-CB 3.35Å; Y388-D392 PolarHBondContact O-N 3.42Å
389	F	95.2	Very high	95	Very high	87 Å²	87	55 Å²	55	38%	0.382	28%	0.28	S	S	.	.	H	α-helix	trans	-68	-34.8	-177.1	-69.9	-68.7	0	0	0	112.6	W247 L385 Y393	W247-F389 HydrophobicContact CD2-CZ 4.4Å; W247-F389 HydrophobicContact CG-CZ 4.29Å; L385-F389 HydrophobicContact CD2-CE2 4.36Å; L385-F389 WeakPolarHBondContact O-CD2 3.15Å; L385-F389 PolarHBondContact O-N 3.32Å; F389-Y393 HydrophobicContact CD1-CD2 4.2Å; F389-Y393 AromaticContact CD1-CE2 3.81Å; F389-Y393 HydrophobicContact CD1-CE2 3.81Å; F389-Y393 HydrophobicContact CE1-CE2 4.43Å; F389-Y393 WeakPolarHBondContact O-CB 3.33Å; F389-Y393 WeakPolarHBondContact O-CD2 3.46Å; F389-Y393 PolarHBondContact O-N 2.94Å
390	A	95.8	Very high	94.9	Very high	37 Å²	37	56.3 Å²	56.3	31%	0.306	29%	0.288	S	S	.	.	H	α-helix	trans	-69.1	-42.7	175.3	0	0	0	0	0	111.9	V386 Y388 L394 V395	V386-A390 WeakPolarHBondContact O-CB 3.27Å; V386-A390 PolarHBondContact O-N 3.19Å; Y388-A390 PolarHBondContact O-N 2.91Å; A390-L394 WeakPolarHBondContact O-CA 3.38Å; A390-L394 VanDerWaalsContact O-CB 3.31Å; A390-L394 WeakPolarHBondContact O-CB 3.32Å; A390-L394 PolarHBondContact O-N 3.49Å; A390-V395 PolarHBondContact O-N 3.35Å; A390-V395 VanDerWaalsContact O-N 3.09Å
391	T	94.8	Very high	94.9	Very high	14 Å²	14	61.9 Å²	61.9	9%	0.086	31%	0.314	C	S	.	.	I	π-helix	trans	-71.3	-44.2	-176.5	-52.4	0	0	0	0	111.3	N347 A351 F387 Y388 V395 Q396	N347-T391 HydrophobicContact CB-CG2 4.4Å; A351-T391 HydrophobicContact CB-CG2 4.23Å; A351-T391 WeakPolarHBondContact CB-OG1 3.43Å; F387-T391 WeakPolarHBondContact O-CB 3.23Å; F387-T391 PolarHBondContact O-N 2.99Å; F387-T391 PolarHBondContact O-OG1 2.91Å; Y388-T391 PolarHBondContact O-N 3.41Å; T391-V395 HydrophobicContact CG2-CB 4.19Å; T391-V395 HydrophobicContact CG2-CG1 4.49Å; T391-V395 PolarHBondContact O-N 3.45Å; T391-Q396 VanDerWaalsContact O-CB 3.29Å; T391-Q396 WeakPolarHBondContact O-CB 3.32Å; T391-Q396 PolarHBondContact O-N 3.42Å
392	D	94	Very high	94.9	Very high	17 Å²	17	63 Å²	63	9%	0.091	32%	0.32	C	S	.	.	I	π-helix	trans	-71.1	-37.4	-176.7	-158.1	46.5	0	0	0	112.3	A342 S343 T348 Y388 Q396	A342-D392 WeakPolarHBondContact CA-OD1 3.45Å; A342-D392 WeakPolarHBondContact CB-OD1 3.31Å; S343-D392 PolarHBondContact N-OD1 3.49Å; T348-D392 HydrophobicContact CG2-CB 4.34Å; Y388-D392 VanDerWaalsContact O-CB 3.27Å; Y388-D392 WeakPolarHBondContact O-CB 3.35Å; Y388-D392 PolarHBondContact O-N 3.42Å; D392-Q396 PolarHBondContact OD1-OE1 3.5Å
393	Y	94	Very high	94.8	Very high	155 Å²	155	63.2 Å²	63.2	61%	0.608	33%	0.328	S	S	*	.	I	π-helix	trans	-99.6	-29	-175.5	-67.9	-87.9	0	0	0	115.1	F389	F389-Y393 HydrophobicContact CD1-CD2 4.2Å; F389-Y393 AromaticContact CD1-CE2 3.81Å; F389-Y393 HydrophobicContact CD1-CE2 3.81Å; F389-Y393 HydrophobicContact CE1-CE2 4.43Å; F389-Y393 WeakPolarHBondContact O-CB 3.33Å; F389-Y393 WeakPolarHBondContact O-CD2 3.46Å; F389-Y393 PolarHBondContact O-N 2.94Å
394	L	94.7	Very high	94.7	Very high	128 Å²	128	67.8 Å²	67.8	67%	0.67	35%	0.348	S	S	*	.	I	π-helix	trans	-108.2	-52.9	-177.7	-72.7	78.8	0	0	0	112.2	A390	A390-L394 WeakPolarHBondContact O-CA 3.38Å; A390-L394 VanDerWaalsContact O-CB 3.31Å; A390-L394 WeakPolarHBondContact O-CB 3.32Å; A390-L394 PolarHBondContact O-N 3.49Å
395	V	94.2	Very high	94.7	Very high	60 Å²	60	72.3 Å²	72.3	36%	0.364	37%	0.369	S	S	.	.	I	π-helix	trans	-71.4	-40.3	-173.6	-177.8	0	0	0	0	110.9	A390 T391 F398 M399	A390-V395 PolarHBondContact O-N 3.35Å; A390-V395 VanDerWaalsContact O-N 3.09Å; T391-V395 HydrophobicContact CG2-CB 4.19Å; T391-V395 HydrophobicContact CG2-CG1 4.49Å; T391-V395 PolarHBondContact O-N 3.45Å; V395-F398 PolarHBondContact O-N 3.05Å; V395-M399 HydrophobicContact CG1-CG 3.72Å; V395-M399 WeakPolarHBondContact O-CG 3.45Å; V395-M399 PolarHBondContact O-N 3.17Å
396	Q	92.5	Very high	94.7	Very high	17 Å²	17	78 Å²	78	8%	0.079	40%	0.395	C	S	.	.	H	α-helix	trans	-62.4	-52.6	-173.9	175.2	179.9	-8	0	0	113.4	S343 G344 T391 D392 F398 M399 D400	S343-Q396 VanDerWaalsContact C-CD 3.47Å; S343-Q396 VanDerWaalsContact C-OE1 3.24Å; S343-Q396 VanDerWaalsContact CB-OE1 3.26Å; S343-Q396 PolarHBondContact O-NE2 3.1Å; S343-Q396 VanDerWaalsContact O-NE2 3.11Å; G344-Q396 VanDerWaalsContact CA-CD 3.42Å; G344-Q396 VanDerWaalsContact CA-OE1 3.25Å; T391-Q396 VanDerWaalsContact O-CB 3.29Å; T391-Q396 WeakPolarHBondContact O-CB 3.32Å; T391-Q396 PolarHBondContact O-N 3.42Å; D392-Q396 PolarHBondContact OD1-OE1 3.5Å; Q396-F398 PolarHBondContact O-N 3.49Å; Q396-F398 VanDerWaalsContact O-N 3.15Å; Q396-M399 PolarHBondContact O-N 3.08Å; Q396-M399 VanDerWaalsContact O-N 3.08Å; Q396-D400 WeakPolarHBondContact CG-OD2 3.3Å; Q396-D400 PolarHBondContact NE2-OD2 2.98Å; Q396-D400 WeakPolarHBondContact O-CB 3.49Å; Q396-D400 VanDerWaalsContact O-CG 3.28Å; Q396-D400 PolarHBondContact O-N 2.96Å
397	P	93.1	Very high	94.7	Very high	69 Å²	69	80 Å²	80	45%	0.448	40%	0.397	S	S	.	.	H	α-helix	trans	-58.1	-33.8	179.3	-25.4	34.7	0	0	0	112.8	Q401	P397-Q401 VanDerWaalsContact O-CG 3.28Å; P397-Q401 WeakPolarHBondContact O-CG 3.38Å; P397-Q401 PolarHBondContact O-N 2.81Å; P397-Q401 VanDerWaalsContact O-N 3.17Å
398	F	94.3	Very high	94.7	Very high	112 Å²	112	84.9 Å²	84.9	49%	0.491	41%	0.414	S	S	.	.	H	α-helix	trans	-69.7	-45.5	175.8	176.9	-116.4	0	0	0	112.1	V395 Q396 D400 Q401 L402 I409	V395-F398 PolarHBondContact O-N 3.05Å; Q396-F398 PolarHBondContact O-N 3.49Å; Q396-F398 VanDerWaalsContact O-N 3.15Å; F398-D400 VanDerWaalsContact C-N 3.35Å; F398-Q401 PolarHBondContact O-N 2.91Å; F398-L402 HydrophobicContact CD1-CD1 4.18Å; F398-L402 HydrophobicContact CE1-CD1 3.68Å; F398-L402 HydrophobicContact CE2-CD1 4.2Å; F398-L402 HydrophobicContact CE2-CG 4.35Å; F398-L402 HydrophobicContact CZ-CD1 3.69Å; F398-L402 HydrophobicContact CZ-CG 4.31Å; F398-L402 WeakPolarHBondContact O-CG 3.36Å; F398-L402 PolarHBondContact O-N 3.06Å; F398-L402 VanDerWaalsContact O-N 3.07Å; F398-I409 HydrophobicContact CE1-CD1 3.67Å; F398-I409 HydrophobicContact CZ-CD1 4.13Å
399	M	93.3	Very high	94.6	Very high	52 Å²	52	93 Å²	93	26%	0.256	46%	0.457	S	S	.	.	H	α-helix	trans	-63.6	-38.8	175.1	-71.5	-63.1	106.6	0	0	112.2	V395 Q396 Q401 L402 A403 I409	V395-M399 HydrophobicContact CG1-CG 3.72Å; V395-M399 WeakPolarHBondContact O-CG 3.45Å; V395-M399 PolarHBondContact O-N 3.17Å; Q396-M399 PolarHBondContact O-N 3.08Å; Q396-M399 VanDerWaalsContact O-N 3.08Å; M399-Q401 VanDerWaalsContact C-N 3.35Å; M399-L402 HydrophobicContact CE-CD1 3.54Å; M399-L402 PolarHBondContact O-N 3.44Å; M399-L402 HydrophobicContact SD-CD1 4.46Å; M399-A403 VanDerWaalsContact O-CB 3.28Å; M399-A403 WeakPolarHBondContact O-CB 3.23Å; M399-A403 PolarHBondContact O-N 3.39Å; M399-I409 HydrophobicContact CE-CD1 3.81Å
400	D	93.8	Very high	94.6	Very high	81 Å²	81	93.3 Å²	93.3	43%	0.433	46%	0.46	S	S	.	.	H	α-helix	trans	-64.4	-40.4	178	-70.7	-16.5	0	0	0	110.9	Q396 F398 A403 F404	Q396-D400 WeakPolarHBondContact CG-OD2 3.3Å; Q396-D400 PolarHBondContact NE2-OD2 2.98Å; Q396-D400 WeakPolarHBondContact O-CB 3.49Å; Q396-D400 VanDerWaalsContact O-CG 3.28Å; Q396-D400 PolarHBondContact O-N 2.96Å; F398-D400 VanDerWaalsContact C-N 3.35Å; D400-A403 PolarHBondContact O-N 3.23Å; D400-F404 VanDerWaalsContact O-CB 3.24Å; D400-F404 WeakPolarHBondContact O-CB 3.11Å; D400-F404 PolarHBondContact O-N 3.32Å
401	Q	94.7	Very high	94.5	Very high	117 Å²	117	96.3 Å²	96.3	55%	0.547	47%	0.468	S	S	.	.	H	α-helix	trans	-65.7	-41.6	174.6	-72.2	-65.8	-17.7	0	0	112.6	P397 F398 M399 H405	P397-Q401 VanDerWaalsContact O-CG 3.28Å; P397-Q401 WeakPolarHBondContact O-CG 3.38Å; P397-Q401 PolarHBondContact O-N 2.81Å; P397-Q401 VanDerWaalsContact O-N 3.17Å; F398-Q401 PolarHBondContact O-N 2.91Å; M399-Q401 VanDerWaalsContact C-N 3.35Å; Q401-H405 PolarHBondContact O-N 2.62Å; Q401-H405 PolarHBondContact O-ND1 3.24Å
402	L	95.1	Very high	94.5	Very high	24 Å²	24	100.8 Å²	100.8	13%	0.126	49%	0.49	C	S	.	.	H	α-helix	trans	-64.1	-46.8	174.8	-71.8	173.6	0	0	0	111.3	F398 M399 F404 H405 Q406 F407 I409	F398-L402 HydrophobicContact CD1-CD1 4.18Å; F398-L402 HydrophobicContact CE1-CD1 3.68Å; F398-L402 HydrophobicContact CE2-CD1 4.2Å; F398-L402 HydrophobicContact CE2-CG 4.35Å; F398-L402 HydrophobicContact CZ-CD1 3.69Å; F398-L402 HydrophobicContact CZ-CG 4.31Å; F398-L402 WeakPolarHBondContact O-CG 3.36Å; F398-L402 PolarHBondContact O-N 3.06Å; F398-L402 VanDerWaalsContact O-N 3.07Å; M399-L402 HydrophobicContact CE-CD1 3.54Å; M399-L402 PolarHBondContact O-N 3.44Å; M399-L402 HydrophobicContact SD-CD1 4.46Å; L402-F404 VanDerWaalsContact C-N 3.35Å; L402-F404 PolarHBondContact O-N 3.45Å; L402-H405 CarbonylContact O-C 3.53Å; L402-H405 PolarHBondContact O-N 3.28Å; L402-Q406 WeakPolarHBondContact O-CA 3.21Å; L402-Q406 PolarHBondContact O-N 3.49Å; L402-F407 HydrophobicContact CD2-CB 3.68Å; L402-F407 HydrophobicContact CD2-CD2 4.37Å; L402-F407 PolarHBondContact O-N 3.26Å; L402-I409 HydrophobicContact CD1-CD1 3.82Å; L402-I409 HydrophobicContact CD1-CG1 3.99Å; L402-I409 HydrophobicContact CD1-CG2 4.16Å; L402-I409 HydrophobicContact CD2-CG2 4.38Å
403	A	94.2	Very high	94.5	Very high	73 Å²	73	105.8 Å²	105.8	60%	0.603	51%	0.513	S	S	*	.	H	α-helix	trans	-63.4	-39.7	179.3	0	0	0	0	0	112	M399 D400 H405 Q406	M399-A403 VanDerWaalsContact O-CB 3.28Å; M399-A403 WeakPolarHBondContact O-CB 3.23Å; M399-A403 PolarHBondContact O-N 3.39Å; D400-A403 PolarHBondContact O-N 3.23Å; A403-H405 PolarHBondContact O-N 3.35Å; A403-Q406 PolarHBondContact O-N 3.39Å; A403-Q406 VanDerWaalsContact O-N 3.14Å
404	F	95.5	Very high	94.6	Very high	169 Å²	169	102.7 Å²	102.7	74%	0.741	51%	0.507	S	S	*	.	H	α-helix	trans	-62.3	-40.9	176.1	-179	-97.4	0	0	0	112.5	D400 L402 Q406	D400-F404 VanDerWaalsContact O-CB 3.24Å; D400-F404 WeakPolarHBondContact O-CB 3.11Å; D400-F404 PolarHBondContact O-N 3.32Å; L402-F404 VanDerWaalsContact C-N 3.35Å; L402-F404 PolarHBondContact O-N 3.45Å; F404-Q406 VanDerWaalsContact C-N 3.29Å
405	H	96.7	Very high	94.6	Very high	96 Å²	96	101 Å²	101	44%	0.444	50%	0.496	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86	-0.5	175.9	-65.3	88.1	0	0	0	113.5	Q401 L402 A403 F407	Q401-H405 PolarHBondContact O-N 2.62Å; Q401-H405 PolarHBondContact O-ND1 3.24Å; L402-H405 CarbonylContact O-C 3.53Å; L402-H405 PolarHBondContact O-N 3.28Å; A403-H405 PolarHBondContact O-N 3.35Å; H405-F407 HydrophobicContact CB-CD1 4.22Å; H405-F407 HydrophobicContact CB-CD2 3.62Å; H405-F407 HydrophobicContact CB-CE1 4.19Å; H405-F407 HydrophobicContact CB-CE2 3.58Å; H405-F407 HydrophobicContact CB-CG 3.95Å; H405-F407 HydrophobicContact CB-CZ 3.88Å; H405-F407 WeakPolarHBondContact O-CD1 3.3Å; H405-F407 PolarHBondContact O-N 3.11Å
406	Q	95.2	Very high	94.6	Very high	141 Å²	141	103.9 Å²	103.9	66%	0.659	51%	0.506	S	S	*	.	T	Hydrogen-bonded Turn	trans	54.9	35.3	-174.2	-156.2	-178.3	-20.5	0	0	113.4	L402 A403 F404 Y408	L402-Q406 WeakPolarHBondContact O-CA 3.21Å; L402-Q406 PolarHBondContact O-N 3.49Å; A403-Q406 PolarHBondContact O-N 3.39Å; A403-Q406 VanDerWaalsContact O-N 3.14Å; F404-Q406 VanDerWaalsContact C-N 3.29Å; Q406-Y408 HydrophobicContact CG-CE2 4.19Å
407	F	96.3	Very high	94.7	Very high	127 Å²	127	110.6 Å²	110.6	56%	0.557	54%	0.539	S	S	*	.			trans	-87.8	145.2	172.8	-62.8	-23.6	0	0	0	110.8	L402 H405	L402-F407 HydrophobicContact CD2-CB 3.68Å; L402-F407 HydrophobicContact CD2-CD2 4.37Å; L402-F407 PolarHBondContact O-N 3.26Å; H405-F407 HydrophobicContact CB-CD1 4.22Å; H405-F407 HydrophobicContact CB-CD2 3.62Å; H405-F407 HydrophobicContact CB-CE1 4.19Å; H405-F407 HydrophobicContact CB-CE2 3.58Å; H405-F407 HydrophobicContact CB-CG 3.95Å; H405-F407 HydrophobicContact CB-CZ 3.88Å; H405-F407 WeakPolarHBondContact O-CD1 3.3Å; H405-F407 PolarHBondContact O-N 3.11Å
408	Y	95.1	Very high	94.9	Very high	196 Å²	196	114.1 Å²	114.1	77%	0.769	55%	0.546	S	S	*	.			trans	-121.6	143.8	178.8	-61.3	-86.5	0	0	0	109.9	Q406	Q406-Y408 HydrophobicContact CG-CE2 4.19Å
409	I	94.4	Very high	94.9	Very high	181 Å²	181	114.3 Å²	114.3	93%	0.928	55%	0.551	S	S	*	*			trans	-130.2	0	177.7	60.1	167.5	0	0	0	112	F398 M399 L402	F398-I409 HydrophobicContact CE1-CD1 3.67Å; F398-I409 HydrophobicContact CZ-CD1 4.13Å; M399-I409 HydrophobicContact CE-CD1 3.81Å; L402-I409 HydrophobicContact CD1-CD1 3.82Å; L402-I409 HydrophobicContact CD1-CG1 3.99Å; L402-I409 HydrophobicContact CD1-CG2 4.16Å; L402-I409 HydrophobicContact CD2-CG2 4.38Å

Retrieved 409 of 409 residues in 930.6 ms (Link to these results)

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