A0A096NX84_PAPAN Loading...

Proteasome activator complex subunit 2

Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.

AlphaFold DB (A0A2K6BQC2), UniProt , Accession A0A096NX84, Species PAPAN (Papio anubis, Olive baboon), Gene PSME2, Length 254 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	49.1	Very low	75.2	Confident	246 Å²	246	131.5 Å²	131.5	100%	1.212	77%	0.772	S	S	*	*				0	115.4	0	-71.8	176	175.1	0	0	108
2	A	57.2	Low	76.8	Confident	102 Å²	102	132 Å²	132	84%	0.843	76%	0.761	S	S	*	*	P	Polyproline II helix	trans	-69.8	130	173.9	0	0	0	0	0	108.8
3	K	66.8	Low	78.2	Confident	196 Å²	196	124.5 Å²	124.5	85%	0.852	73%	0.725	S	S	*	*	P	Polyproline II helix	trans	-62.9	134.4	171.5	-80.7	-179	175.7	178.2	0	108.3	C5	K3-C5 PolarHBondContact O-N 3.38Å; K3-C5 VanDerWaalsContact O-N 3.08Å
4	P	65.4	Low	79.3	Confident	128 Å²	128	127 Å²	127	83%	0.831	72%	0.716	S	S	*	*	P	Polyproline II helix	trans	-61	116.8	175.7	22.1	-29.4	0	0	0	109.3	G6	P4-G6 PolarHBondContact O-N 3.15Å
5	C	70.6	Confident	80.4	Confident	122 Å²	122	128.7 Å²	128.7	82%	0.824	71%	0.713	S	S	*	*			trans	-86.8	89.2	174.3	-168.1	0	0	0	0	108.1	K3	K3-C5 PolarHBondContact O-N 3.38Å; K3-C5 VanDerWaalsContact O-N 3.08Å
6	G	72.9	Confident	81.4	Confident	75 Å²	75	128.6 Å²	128.6	77%	0.773	71%	0.705	S	S	*	*			trans	-86.3	105.4	174.6	0	0	0	0	0	110.5	P4 R8	P4-G6 PolarHBondContact O-N 3.15Å; G6-R8 PolarHBondContact O-N 3Å
7	V	82.9	Confident	82.3	Confident	120 Å²	120	126.5 Å²	126.5	73%	0.727	70%	0.697	S	S	*	*			trans	-81.3	115.2	173	-179.2	0	0	0	0	109.1	L9	V7-L9 HydrophobicContact CG1-CD2 4.24Å
8	R	86.7	Confident	83	Confident	238 Å²	238	123 Å²	123	90%	0.898	68%	0.675	S	S	*	*			trans	-101.7	109.1	172.7	-171.4	177.7	-179.7	-179.8	0.6	109.7	G6	G6-R8 PolarHBondContact O-N 3Å
9	L	88.7	Confident	83.8	Confident	99 Å²	99	120.7 Å²	120.7	52%	0.518	66%	0.664	S	S	.	*			trans	-72.2	134.4	175.8	-60.1	171.9	0	0	0	110.6	V7 R14	V7-L9 HydrophobicContact CG1-CD2 4.24Å; L9-R14 HydrophobicContact CB-CG 4.12Å
10	S	93.3	Very high	84.5	Confident	68 Å²	68	119.9 Å²	119.9	48%	0.476	65%	0.654	S	S	.	*			trans	-68.5	155.2	173.7	73.2	0	0	0	0	110.9	E12 A13 R14	S10-E12 VanDerWaalsContact C-N 3.25Å; S10-E12 PolarHBondContact O-N 3.21Å; S10-A13 PolarHBondContact O-N 3.02Å; S10-A13 VanDerWaalsContact OG-CB 3.31Å; S10-A13 WeakPolarHBondContact OG-CB 3.4Å; S10-A13 PolarHBondContact OG-N 3.32Å; S10-A13 VanDerWaalsContact OG-N 3.15Å; S10-R14 PolarHBondContact O-N 3.49Å
11	G	93.6	Very high	85.1	Confident	52 Å²	52	119.3 Å²	119.3	54%	0.536	64%	0.642	S	S	.	*	H	α-helix	trans	-62	-35	177.3	0	0	0	0	0	112.7	K15	G11-K15 WeakPolarHBondContact O-CG 3.29Å; G11-K15 PolarHBondContact O-N 2.8Å; G11-K15 VanDerWaalsContact O-N 3.15Å
12	E	94.9	Very high	87.4	Confident	138 Å²	138	113 Å²	113	65%	0.645	61%	0.61	S	S	*	*	H	α-helix	trans	-67	-45.9	176.4	-174.5	175.1	-174.8	0	0	112.2	S10 R14 K15 Q16	S10-E12 VanDerWaalsContact C-N 3.25Å; S10-E12 PolarHBondContact O-N 3.21Å; E12-R14 VanDerWaalsContact C-N 3.28Å; E12-R14 PolarHBondContact O-N 3.47Å; E12-K15 PolarHBondContact O-N 3.11Å; E12-K15 VanDerWaalsContact O-N 3.11Å; E12-Q16 PolarHBondContact O-N 3.19Å
13	A	94.9	Very high	89.3	Confident	35 Å²	35	112.3 Å²	112.3	29%	0.289	59%	0.592	S	S	.	*	H	α-helix	trans	-59.5	-40.1	177.6	0	0	0	0	0	111.7	S10 Q16 V17	S10-A13 PolarHBondContact O-N 3.02Å; S10-A13 VanDerWaalsContact OG-CB 3.31Å; S10-A13 WeakPolarHBondContact OG-CB 3.4Å; S10-A13 PolarHBondContact OG-N 3.32Å; S10-A13 VanDerWaalsContact OG-N 3.15Å; A13-Q16 PolarHBondContact O-N 3.3Å; A13-V17 PolarHBondContact O-N 3.5Å
14	R	93.5	Very high	90.8	Very high	159 Å²	159	103.5 Å²	103.5	60%	0.6	55%	0.554	S	S	*	*	H	α-helix	trans	-63	-43.3	175	-71	-178.4	-177.8	176.3	-0.3	112.3	L9 S10 E12 Q16 V17 E18	L9-R14 HydrophobicContact CB-CG 4.12Å; S10-R14 PolarHBondContact O-N 3.49Å; E12-R14 VanDerWaalsContact C-N 3.28Å; E12-R14 PolarHBondContact O-N 3.47Å; R14-Q16 PolarHBondContact O-N 3.15Å; R14-V17 PolarHBondContact O-N 3.05Å; R14-E18 VanDerWaalsContact O-CB 3.32Å; R14-E18 WeakPolarHBondContact O-CB 3.25Å; R14-E18 PolarHBondContact O-N 3.36Å
15	K	95.5	Very high	92.3	Very high	153 Å²	153	100.5 Å²	100.5	67%	0.665	53%	0.528	S	S	*	.	H	α-helix	trans	-62.4	-42.2	179	-74.8	178.5	-179.8	-174.8	0	112	G11 E12 V17 E18 V19	G11-K15 WeakPolarHBondContact O-CG 3.29Å; G11-K15 PolarHBondContact O-N 2.8Å; G11-K15 VanDerWaalsContact O-N 3.15Å; E12-K15 PolarHBondContact O-N 3.11Å; E12-K15 VanDerWaalsContact O-N 3.11Å; K15-V17 PolarHBondContact O-N 3.45Å; K15-E18 PolarHBondContact O-N 3.32Å; K15-V19 WeakPolarHBondContact O-CG2 3.37Å; K15-V19 PolarHBondContact O-N 3.01Å
16	Q	96.2	Very high	93.6	Very high	127 Å²	127	100.1 Å²	100.1	59%	0.593	51%	0.514	S	S	*	.	H	α-helix	trans	-61.1	-45.8	179.3	-69.7	177.2	2.5	0	0	112	E12 A13 R14 F20	E12-Q16 PolarHBondContact O-N 3.19Å; A13-Q16 PolarHBondContact O-N 3.3Å; R14-Q16 PolarHBondContact O-N 3.15Å; Q16-F20 PolarHBondContact O-N 3.06Å
17	V	96.3	Very high	94.8	Very high	93 Å²	93	101.5 Å²	101.5	56%	0.564	50%	0.5	S	S	*	.	H	α-helix	trans	-68.5	-37.2	177.7	177.6	0	0	0	0	111.5	A13 R14 K15 F20 R21	A13-V17 PolarHBondContact O-N 3.5Å; R14-V17 PolarHBondContact O-N 3.05Å; K15-V17 PolarHBondContact O-N 3.45Å; V17-F20 PolarHBondContact O-N 2.9Å; V17-R21 WeakPolarHBondContact O-CB 3.31Å; V17-R21 PolarHBondContact O-N 3.33Å
18	E	95.6	Very high	95.5	Very high	63 Å²	63	95.8 Å²	95.8	29%	0.294	47%	0.466	S	S	.	.	H	α-helix	trans	-64.1	-41.1	178.6	-173.1	58.5	-154.2	0	0	112.2	R14 K15 F20 R21 Q22	R14-E18 VanDerWaalsContact O-CB 3.32Å; R14-E18 WeakPolarHBondContact O-CB 3.25Å; R14-E18 PolarHBondContact O-N 3.36Å; K15-E18 PolarHBondContact O-N 3.32Å; E18-F20 PolarHBondContact O-N 3.47Å; E18-R21 PolarHBondContact O-N 2.91Å; E18-R21 IonicContact OE1-CZ 3.54Å; E18-R21 IonicContact OE1-NE 2.72Å; E18-R21 PolarHBondContact OE1-NE 3.47Å; E18-R21 IonicContact OE1-NH2 2.77Å; E18-R21 PolarHBondContact OE1-NH2 2.94Å; E18-R21 IonicContact OE2-CZ 3.26Å; E18-R21 VanDerWaalsContact OE2-CZ 3.26Å; E18-R21 IonicContact OE2-NE 3.46Å; E18-R21 PolarHBondContact OE2-NE 2.77Å; E18-R21 VanDerWaalsContact OE2-NE 3.12Å; E18-R21 IonicContact OE2-NH2 2.94Å; E18-R21 PolarHBondContact OE2-NH2 3.46Å; E18-Q22 WeakPolarHBondContact O-CG 3.35Å; E18-Q22 PolarHBondContact O-N 3.3Å; E18-Q22 PolarHBondContact OE1-NE2 3.3Å
19	V	97.6	Very high	95.9	Very high	79 Å²	79	89 Å²	89	48%	0.479	44%	0.444	S	S	.	.	H	α-helix	trans	-60.7	-45.5	174.7	170.4	0	0	0	0	110.9	K15 R21 Q22 N23	K15-V19 WeakPolarHBondContact O-CG2 3.37Å; K15-V19 PolarHBondContact O-N 3.01Å; V19-R21 VanDerWaalsContact C-N 3.34Å; V19-R21 PolarHBondContact O-N 3.46Å; V19-Q22 PolarHBondContact O-N 3.34Å; V19-N23 VanDerWaalsContact O-CG 3.27Å; V19-N23 PolarHBondContact O-N 3.24Å; V19-N23 PolarHBondContact O-ND2 3.12Å
20	F	97.8	Very high	96.4	Very high	104 Å²	104	88 Å²	88	46%	0.456	44%	0.437	S	S	.	.	H	α-helix	trans	-58.6	-46.2	175	167.7	-98.8	0	0	0	111.6	Q16 V17 E18 Q22 N23 L24 T138 H142	Q16-F20 PolarHBondContact O-N 3.06Å; V17-F20 PolarHBondContact O-N 2.9Å; E18-F20 PolarHBondContact O-N 3.47Å; F20-Q22 PolarHBondContact O-N 3.45Å; F20-N23 PolarHBondContact O-N 2.92Å; F20-L24 HydrophobicContact CE1-CD2 4.19Å; F20-L24 HydrophobicContact CZ-CD2 4.39Å; F20-L24 WeakPolarHBondContact O-CB 3.32Å; F20-L24 PolarHBondContact O-N 3.39Å; F20-T138 HydrophobicContact CZ-CG2 4.43Å; F20-H142 AromaticContact CE1-NE2 3.91Å
21	R	97.3	Very high	96.6	Very high	109 Å²	109	84.9 Å²	84.9	41%	0.411	42%	0.415	S	S	.	.	H	α-helix	trans	-61.7	-43.7	-179.9	-171.7	178	71.3	148.6	5.3	111.8	V17 E18 V19 L24 F25	V17-R21 WeakPolarHBondContact O-CB 3.31Å; V17-R21 PolarHBondContact O-N 3.33Å; E18-R21 PolarHBondContact O-N 2.91Å; E18-R21 IonicContact OE1-CZ 3.54Å; E18-R21 IonicContact OE1-NE 2.72Å; E18-R21 PolarHBondContact OE1-NE 3.47Å; E18-R21 IonicContact OE1-NH2 2.77Å; E18-R21 PolarHBondContact OE1-NH2 2.94Å; E18-R21 IonicContact OE2-CZ 3.26Å; E18-R21 VanDerWaalsContact OE2-CZ 3.26Å; E18-R21 IonicContact OE2-NE 3.46Å; E18-R21 PolarHBondContact OE2-NE 2.77Å; E18-R21 VanDerWaalsContact OE2-NE 3.12Å; E18-R21 IonicContact OE2-NH2 2.94Å; E18-R21 PolarHBondContact OE2-NH2 3.46Å; V19-R21 VanDerWaalsContact C-N 3.34Å; V19-R21 PolarHBondContact O-N 3.46Å; R21-L24 WeakPolarHBondContact O-CB 3.34Å; R21-L24 PolarHBondContact O-N 3.29Å; R21-F25 HydrophobicContact CG-CD2 4.01Å; R21-F25 HydrophobicContact CG-CE2 3.77Å; R21-F25 WeakPolarHBondContact O-CD2 3.5Å; R21-F25 PolarHBondContact O-N 3.08Å
22	Q	97.3	Very high	96.6	Very high	112 Å²	112	83.2 Å²	83.2	52%	0.523	39%	0.393	S	S	.	.	H	α-helix	trans	-62.8	-45	178	-72.3	174.7	3.2	0	0	111.6	E18 V19 F20 F25 Q26	E18-Q22 WeakPolarHBondContact O-CG 3.35Å; E18-Q22 PolarHBondContact O-N 3.3Å; E18-Q22 PolarHBondContact OE1-NE2 3.3Å; V19-Q22 PolarHBondContact O-N 3.34Å; F20-Q22 PolarHBondContact O-N 3.45Å; Q22-F25 PolarHBondContact O-N 3.49Å; Q22-Q26 PolarHBondContact O-N 2.84Å
23	N	98.1	Very high	96.5	Very high	89 Å²	89	83.7 Å²	83.7	48%	0.476	39%	0.391	S	S	.	.	H	α-helix	trans	-62.2	-45.3	176.4	-67.4	-13.8	0	0	0	111.7	V19 F20 F25 Q26 E27	V19-N23 VanDerWaalsContact O-CG 3.27Å; V19-N23 PolarHBondContact O-N 3.24Å; V19-N23 PolarHBondContact O-ND2 3.12Å; F20-N23 PolarHBondContact O-N 2.92Å; N23-F25 VanDerWaalsContact C-N 3.3Å; N23-F25 PolarHBondContact O-N 2.94Å; N23-Q26 PolarHBondContact O-N 3.41Å; N23-E27 WeakPolarHBondContact O-CB 3.17Å; N23-E27 WeakPolarHBondContact O-CG 3.44Å; N23-E27 PolarHBondContact O-N 3.49Å
24	L	98.2	Very high	96.6	Very high	10 Å²	10	88.5 Å²	88.5	5%	0.052	40%	0.401	C	S	.	.	H	α-helix	trans	-55.3	-45.5	176.6	172.2	66.5	0	0	0	111.7	F20 R21 A28 L135 T138 W139 H142	F20-L24 HydrophobicContact CE1-CD2 4.19Å; F20-L24 HydrophobicContact CZ-CD2 4.39Å; F20-L24 WeakPolarHBondContact O-CB 3.32Å; F20-L24 PolarHBondContact O-N 3.39Å; R21-L24 WeakPolarHBondContact O-CB 3.34Å; R21-L24 PolarHBondContact O-N 3.29Å; L24-A28 WeakPolarHBondContact O-CB 3.42Å; L24-A28 PolarHBondContact O-N 3.21Å; L24-L135 HydrophobicContact CD1-CD1 3.59Å; L24-T138 HydrophobicContact CD1-CG2 4.23Å; L24-T138 HydrophobicContact CD2-CG2 3.88Å; L24-W139 HydrophobicContact CD1-CB 4.35Å; L24-W139 HydrophobicContact CG-CB 4.43Å; L24-H142 HydrophobicContact CD2-CB 4.48Å
25	F	97.6	Very high	96.8	Very high	66 Å²	66	83.6 Å²	83.6	29%	0.289	38%	0.384	S	S	.	.	H	α-helix	trans	-69.4	-41.5	-178.5	-83.9	-127.3	0	0	0	111.3	R21 Q22 N23 E27 A28 E29 W139 H142 L143	R21-F25 HydrophobicContact CG-CD2 4.01Å; R21-F25 HydrophobicContact CG-CE2 3.77Å; R21-F25 WeakPolarHBondContact O-CD2 3.5Å; R21-F25 PolarHBondContact O-N 3.08Å; Q22-F25 PolarHBondContact O-N 3.49Å; N23-F25 VanDerWaalsContact C-N 3.3Å; N23-F25 PolarHBondContact O-N 2.94Å; F25-E27 PolarHBondContact O-N 3Å; F25-A28 PolarHBondContact O-N 3.43Å; F25-E29 WeakPolarHBondContact O-CB 3.24Å; F25-E29 PolarHBondContact O-N 2.97Å; F25-W139 AromaticContact CD2-CD1 3.93Å; F25-H142 HydrophobicContact CE2-CB 3.91Å; F25-H142 HydrophobicContact CZ-CB 4.29Å; F25-L143 HydrophobicContact CE1-CD2 3.6Å; F25-L143 HydrophobicContact CE1-CG 4.37Å; F25-L143 HydrophobicContact CZ-CD2 3.68Å; F25-L143 HydrophobicContact CZ-CG 4.11Å
26	Q	97.8	Very high	96.9	Very high	114 Å²	114	76.3 Å²	76.3	53%	0.533	35%	0.353	S	S	.	.	H	α-helix	trans	-63.6	-40.8	176.3	-173	61.2	73	0	0	112.2	Q22 N23 E29 E30	Q22-Q26 PolarHBondContact O-N 2.84Å; N23-Q26 PolarHBondContact O-N 3.41Å; Q26-E29 PolarHBondContact O-N 2.97Å; Q26-E30 PolarHBondContact O-N 3.35Å
27	E	97.9	Very high	96.9	Very high	103 Å²	103	72.3 Å²	72.3	48%	0.481	34%	0.338	S	S	.	.	H	α-helix	trans	-67.2	-40.1	176.2	-76.6	-176.3	-147.3	0	0	112.2	N23 F25 E29 E30 F31 L135	N23-E27 WeakPolarHBondContact O-CB 3.17Å; N23-E27 WeakPolarHBondContact O-CG 3.44Å; N23-E27 PolarHBondContact O-N 3.49Å; F25-E27 PolarHBondContact O-N 3Å; E27-E29 VanDerWaalsContact C-N 3.31Å; E27-E30 PolarHBondContact O-N 2.89Å; E27-F31 VanDerWaalsContact O-CB 3.24Å; E27-F31 WeakPolarHBondContact O-CB 3.29Å; E27-F31 PolarHBondContact O-N 3.5Å; E27-L135 HydrophobicContact CB-CD1 3.96Å; E27-L135 HydrophobicContact CB-CD2 4.24Å
28	A	97.4	Very high	97	Very high	0 Å²	0	73 Å²	73	0%	0	34%	0.335	C	S	.	.	H	α-helix	trans	-64.1	-38.2	175.6	0	0	0	0	0	111.6	L24 F25 F31 L32 W139	L24-A28 WeakPolarHBondContact O-CB 3.42Å; L24-A28 PolarHBondContact O-N 3.21Å; F25-A28 PolarHBondContact O-N 3.43Å; A28-F31 WeakPolarHBondContact O-CB 3.46Å; A28-F31 PolarHBondContact O-N 3Å; A28-L32 WeakPolarHBondContact O-CG 3.18Å; A28-L32 PolarHBondContact O-N 3.39Å; A28-L32 VanDerWaalsContact O-N 3.12Å; A28-W139 HydrophobicContact CB-CB 3.94Å; A28-W139 HydrophobicContact CB-CD2 3.73Å; A28-W139 HydrophobicContact CB-CE3 4.32Å; A28-W139 HydrophobicContact CB-CG 3.53Å
29	E	95.4	Very high	97.1	Very high	96 Å²	96	71.6 Å²	71.6	45%	0.449	33%	0.328	S	S	.	.	H	α-helix	trans	-63.9	-52.6	174.6	-174.9	170.1	-157.7	0	0	111.9	F25 Q26 E27 F31 L32 Y33	F25-E29 WeakPolarHBondContact O-CB 3.24Å; F25-E29 PolarHBondContact O-N 2.97Å; Q26-E29 PolarHBondContact O-N 2.97Å; E27-E29 VanDerWaalsContact C-N 3.31Å; E29-F31 PolarHBondContact O-N 3.26Å; E29-L32 PolarHBondContact O-N 3.35Å; E29-L32 VanDerWaalsContact O-N 3.14Å; E29-Y33 HydrophobicContact CG-CD2 3.47Å; E29-Y33 VanDerWaalsContact CG-CD2 3.47Å; E29-Y33 HydrophobicContact CG-CE2 3.6Å; E29-Y33 VanDerWaalsContact O-CD2 3.29Å; E29-Y33 WeakPolarHBondContact O-CD2 3.37Å; E29-Y33 PolarHBondContact O-N 3.03Å
30	E	97.7	Very high	97.2	Very high	77 Å²	77	70 Å²	70	36%	0.36	32%	0.316	S	S	.	.	H	α-helix	trans	-59.7	-35.3	176.9	178.8	67	175.7	0	0	111.4	Q26 E27 R34 F35	Q26-E30 PolarHBondContact O-N 3.35Å; E27-E30 PolarHBondContact O-N 2.89Å; E30-R34 PolarHBondContact O-N 3.25Å; E30-R34 VanDerWaalsContact O-N 3.1Å; E30-R34 WeakPolarHBondContact OE1-CD 3.41Å; E30-R34 IonicContact OE1-CZ 3.12Å; E30-R34 IonicContact OE1-NE 2.84Å; E30-R34 PolarHBondContact OE1-NE 3.48Å; E30-R34 IonicContact OE1-NH1 3.35Å; E30-R34 PolarHBondContact OE1-NH1 3Å; E30-F35 PolarHBondContact O-N 3.01Å
31	F	97.6	Very high	97.2	Very high	4 Å²	4	69.9 Å²	69.9	2%	0.018	32%	0.319	C	S	.	.	I	π-helix	trans	-59.3	-50.8	175	170	-108.3	0	0	0	111.7	E27 A28 E29 F35 L36 K132 L135 V136 Y228	E27-F31 VanDerWaalsContact O-CB 3.24Å; E27-F31 WeakPolarHBondContact O-CB 3.29Å; E27-F31 PolarHBondContact O-N 3.5Å; A28-F31 WeakPolarHBondContact O-CB 3.46Å; A28-F31 PolarHBondContact O-N 3Å; E29-F31 PolarHBondContact O-N 3.26Å; F31-F35 HydrophobicContact CD2-CB 4.25Å; F31-F35 AromaticContact CD2-CD1 3.59Å; F31-F35 HydrophobicContact CD2-CD1 3.59Å; F31-F35 HydrophobicContact CD2-CE1 4.34Å; F31-F35 HydrophobicContact CD2-CG 4.25Å; F31-F35 AromaticContact CE2-CD1 3.81Å; F31-F35 HydrophobicContact CE2-CD1 3.81Å; F31-F35 HydrophobicContact CE2-CE1 4.3Å; F31-F35 PolarHBondContact O-N 3.14Å; F31-L36 HydrophobicContact CE1-CD1 3.97Å; F31-L36 HydrophobicContact CE2-CB 4.13Å; F31-L36 HydrophobicContact CE2-CD1 4.45Å; F31-L36 HydrophobicContact CZ-CB 4.23Å; F31-L36 HydrophobicContact CZ-CD1 3.75Å; F31-L36 HydrophobicContact CZ-CG 4.33Å; F31-L36 WeakPolarHBondContact O-CB 3.5Å; F31-L36 PolarHBondContact O-N 2.85Å; F31-K132 HydrophobicContact CD2-CB 3.96Å; F31-K132 HydrophobicContact CD2-CD 4.04Å; F31-K132 HydrophobicContact CD2-CG 3.85Å; F31-K132 HydrophobicContact CE2-CB 3.54Å; F31-K132 HydrophobicContact CE2-CD 4.45Å; F31-K132 HydrophobicContact CE2-CG 3.76Å; F31-K132 HydrophobicContact CZ-CB 4.02Å; F31-L135 HydrophobicContact CB-CD2 4.1Å; F31-L135 HydrophobicContact CG-CD2 4.48Å; F31-V136 HydrophobicContact CD1-CG2 3.68Å; F31-V136 HydrophobicContact CE1-CG2 3.43Å; F31-V136 VanDerWaalsContact CE1-CG2 3.43Å; F31-V136 HydrophobicContact CZ-CG2 4.33Å; F31-Y228 HydrophobicContact CE2-CD1 4.46Å; F31-Y228 HydrophobicContact CE2-CE1 4.06Å; F31-Y228 HydrophobicContact CZ-CD1 4.49Å; F31-Y228 HydrophobicContact CZ-CE1 4.41Å
32	L	94.3	Very high	97.2	Very high	16 Å²	16	68.9 Å²	68.9	8%	0.084	32%	0.316	C	S	.	.	I	π-helix	trans	-72	-44.6	-175	-67.8	173	0	0	0	112.6	A28 E29 P37 W139 I235	A28-L32 WeakPolarHBondContact O-CG 3.18Å; A28-L32 PolarHBondContact O-N 3.39Å; A28-L32 VanDerWaalsContact O-N 3.12Å; E29-L32 PolarHBondContact O-N 3.35Å; E29-L32 VanDerWaalsContact O-N 3.14Å; L32-P37 WeakPolarHBondContact O-CD 3.11Å; L32-W139 HydrophobicContact CD1-CH2 3.89Å; L32-W139 HydrophobicContact CD1-CZ3 4.07Å; L32-I235 HydrophobicContact CD1-CG2 3.83Å; L32-I235 HydrophobicContact CD2-CB 4.3Å; L32-I235 HydrophobicContact CD2-CD1 3.87Å; L32-I235 HydrophobicContact CD2-CG2 3.85Å
33	Y	92.8	Very high	97.3	Very high	149 Å²	149	63.5 Å²	63.5	58%	0.584	29%	0.291	S	S	*	.	I	π-helix	trans	-83.8	-31	-171.8	-71.2	-65.3	0	0	0	113.9	E29	E29-Y33 HydrophobicContact CG-CD2 3.47Å; E29-Y33 VanDerWaalsContact CG-CD2 3.47Å; E29-Y33 HydrophobicContact CG-CE2 3.6Å; E29-Y33 VanDerWaalsContact O-CD2 3.29Å; E29-Y33 WeakPolarHBondContact O-CD2 3.37Å; E29-Y33 PolarHBondContact O-N 3.03Å
34	R	96.6	Very high	97.3	Very high	135 Å²	135	62.6 Å²	62.6	51%	0.509	29%	0.286	S	S	.	.	I	π-helix	trans	-121	-57.3	-173.3	-176.7	169.5	146.5	-158.1	9.9	112.9	E30 L36 Q38	E30-R34 PolarHBondContact O-N 3.25Å; E30-R34 VanDerWaalsContact O-N 3.1Å; E30-R34 WeakPolarHBondContact OE1-CD 3.41Å; E30-R34 IonicContact OE1-CZ 3.12Å; E30-R34 IonicContact OE1-NE 2.84Å; E30-R34 PolarHBondContact OE1-NE 3.48Å; E30-R34 IonicContact OE1-NH1 3.35Å; E30-R34 PolarHBondContact OE1-NH1 3Å; R34-L36 PolarHBondContact O-N 3.48Å; R34-Q38 WeakPolarHBondContact O-CB 3.36Å; R34-Q38 WeakPolarHBondContact O-CG 3.46Å; R34-Q38 PolarHBondContact O-N 3.1Å
35	F	98.3	Very high	97.3	Very high	57 Å²	57	67.5 Å²	67.5	25%	0.25	31%	0.309	C	S	.	.	I	π-helix	trans	-62.8	-48.6	-170.6	-175.8	-90.8	0	0	0	112.3	E30 F31 Q38 K39 T128 K132 Y228	E30-F35 PolarHBondContact O-N 3.01Å; F31-F35 HydrophobicContact CD2-CB 4.25Å; F31-F35 AromaticContact CD2-CD1 3.59Å; F31-F35 HydrophobicContact CD2-CD1 3.59Å; F31-F35 HydrophobicContact CD2-CE1 4.34Å; F31-F35 HydrophobicContact CD2-CG 4.25Å; F31-F35 AromaticContact CE2-CD1 3.81Å; F31-F35 HydrophobicContact CE2-CD1 3.81Å; F31-F35 HydrophobicContact CE2-CE1 4.3Å; F31-F35 PolarHBondContact O-N 3.14Å; F35-Q38 PolarHBondContact O-N 2.87Å; F35-K39 HydrophobicContact CD1-CG 3.9Å; F35-K39 HydrophobicContact CE1-CD 4.37Å; F35-K39 HydrophobicContact CE1-CG 3.49Å; F35-K39 VanDerWaalsContact CE1-CG 3.49Å; F35-K39 HydrophobicContact CE2-CG 4.41Å; F35-K39 HydrophobicContact CZ-CD 4.23Å; F35-K39 VanDerWaalsContact CZ-CE 3.47Å; F35-K39 HydrophobicContact CZ-CG 3.77Å; F35-K39 WeakPolarHBondContact O-CB 3.45Å; F35-K39 WeakPolarHBondContact O-CG 3.49Å; F35-K39 PolarHBondContact O-N 3.21Å; F35-T128 HydrophobicContact CE1-CG2 4.11Å; F35-T128 HydrophobicContact CZ-CG2 3.53Å; F35-K132 HydrophobicContact CD1-CG 4.46Å; F35-K132 HydrophobicContact CE1-CG 3.94Å; F35-K132 HydrophobicContact CZ-CG 4.5Å; F35-Y228 HydrophobicContact CE1-CE1 4.32Å
36	L	97	Very high	97.3	Very high	0 Å²	0	65 Å²	65	0%	0	30%	0.298	C	S	.	.	H	α-helix	trans	-64.7	-53.3	-174.4	-175.3	169.5	0	0	0	111.5	F31 R34 Q38 K39 I40 Y228 L231 Y232	F31-L36 HydrophobicContact CE1-CD1 3.97Å; F31-L36 HydrophobicContact CE2-CB 4.13Å; F31-L36 HydrophobicContact CE2-CD1 4.45Å; F31-L36 HydrophobicContact CZ-CB 4.23Å; F31-L36 HydrophobicContact CZ-CD1 3.75Å; F31-L36 HydrophobicContact CZ-CG 4.33Å; F31-L36 WeakPolarHBondContact O-CB 3.5Å; F31-L36 PolarHBondContact O-N 2.85Å; R34-L36 PolarHBondContact O-N 3.48Å; L36-Q38 VanDerWaalsContact C-N 3.26Å; L36-Q38 PolarHBondContact O-N 3.27Å; L36-K39 PolarHBondContact O-N 3.38Å; L36-I40 HydrophobicContact CD2-CD1 3.51Å; L36-I40 HydrophobicContact CD2-CG1 4.08Å; L36-I40 PolarHBondContact O-N 2.84Å; L36-Y228 HydrophobicContact CD1-CD1 4.43Å; L36-Y228 WeakPolarHBondContact CD2-O 3.21Å; L36-Y228 HydrophobicContact CG-CD1 3.89Å; L36-Y228 HydrophobicContact CG-CG 4.45Å; L36-L231 HydrophobicContact CD1-CB 4.46Å; L36-Y232 HydrophobicContact CD1-CD2 4.29Å; L36-Y232 HydrophobicContact CD2-CD2 3.95Å; L36-Y232 HydrophobicContact CD2-CG 4.03Å
37	P	96.9	Very high	97.3	Very high	43 Å²	43	59.8 Å²	59.8	28%	0.279	27%	0.274	S	S	.	.	H	α-helix	trans	-56.2	-40.8	177	-26.7	35.2	0	0	0	112.7	L32 K39 I40 I41 Y232	L32-P37 WeakPolarHBondContact O-CD 3.11Å; P37-K39 PolarHBondContact O-N 2.92Å; P37-I40 PolarHBondContact O-N 2.8Å; P37-I41 PolarHBondContact O-N 3.12Å; P37-Y232 HydrophobicContact CG-CE2 4.34Å
38	Q	98.2	Very high	97.3	Very high	108 Å²	108	61 Å²	61	51%	0.505	28%	0.28	S	S	.	.	H	α-helix	trans	-62.8	-41.1	176.2	-72.2	176.1	-6.3	0	0	111.9	R34 F35 L36 I40 I41 Y42	R34-Q38 WeakPolarHBondContact O-CB 3.36Å; R34-Q38 WeakPolarHBondContact O-CG 3.46Å; R34-Q38 PolarHBondContact O-N 3.1Å; F35-Q38 PolarHBondContact O-N 2.87Å; L36-Q38 VanDerWaalsContact C-N 3.26Å; L36-Q38 PolarHBondContact O-N 3.27Å; Q38-I40 PolarHBondContact O-N 3.44Å; Q38-I41 PolarHBondContact O-N 2.87Å; Q38-Y42 WeakPolarHBondContact O-CB 3.39Å; Q38-Y42 PolarHBondContact O-N 3.24Å
39	K	98.3	Very high	97.3	Very high	32 Å²	32	66.2 Å²	66.2	14%	0.139	30%	0.304	C	S	.	.	H	α-helix	trans	-64.8	-37	177	-83	-64.9	-174	176.4	0	113.1	F35 L36 P37 I41 Y42 L43 E125 Y228	F35-K39 HydrophobicContact CD1-CG 3.9Å; F35-K39 HydrophobicContact CE1-CD 4.37Å; F35-K39 HydrophobicContact CE1-CG 3.49Å; F35-K39 VanDerWaalsContact CE1-CG 3.49Å; F35-K39 HydrophobicContact CE2-CG 4.41Å; F35-K39 HydrophobicContact CZ-CD 4.23Å; F35-K39 VanDerWaalsContact CZ-CE 3.47Å; F35-K39 HydrophobicContact CZ-CG 3.77Å; F35-K39 WeakPolarHBondContact O-CB 3.45Å; F35-K39 WeakPolarHBondContact O-CG 3.49Å; F35-K39 PolarHBondContact O-N 3.21Å; L36-K39 PolarHBondContact O-N 3.38Å; P37-K39 PolarHBondContact O-N 2.92Å; K39-I41 VanDerWaalsContact C-N 3.34Å; K39-I41 PolarHBondContact O-N 2.9Å; K39-Y42 HydrophobicContact CD-CD1 4.27Å; K39-Y42 PolarHBondContact O-N 3.28Å; K39-L43 WeakPolarHBondContact O-CB 3.46Å; K39-L43 VanDerWaalsContact O-CG 3.28Å; K39-L43 WeakPolarHBondContact O-CG 3.39Å; K39-L43 PolarHBondContact O-N 3.5Å; K39-E125 IonicContact NZ-OE1 3.38Å; K39-E125 PolarHBondContact NZ-OE1 3.34Å; K39-E125 IonicContact NZ-OE2 3.78Å; K39-E125 PolarHBondContact NZ-OE2 2.98Å; K39-Y228 HydrophobicContact CB-CD2 4.19Å; K39-Y228 HydrophobicContact CB-CE1 4.45Å; K39-Y228 HydrophobicContact CB-CE2 4.04Å; K39-Y228 HydrophobicContact CB-CG 4.48Å; K39-Y228 HydrophobicContact CG-CE2 4.41Å
40	I	98.3	Very high	97.3	Very high	46 Å²	46	68.4 Å²	68.4	24%	0.236	32%	0.319	C	S	.	.	H	α-helix	trans	-60.5	-46.5	174.7	-66.4	172.2	0	0	0	110.5	L36 P37 Q38 N44 R225 A229	L36-I40 HydrophobicContact CD2-CD1 3.51Å; L36-I40 HydrophobicContact CD2-CG1 4.08Å; L36-I40 PolarHBondContact O-N 2.84Å; P37-I40 PolarHBondContact O-N 2.8Å; Q38-I40 PolarHBondContact O-N 3.44Å; I40-N44 WeakPolarHBondContact O-CB 3.48Å; I40-N44 PolarHBondContact O-N 2.86Å; I40-R225 HydrophobicContact CG2-CG 4.23Å; I40-A229 HydrophobicContact CD1-CB 4Å
41	I	98.3	Very high	97.2	Very high	102 Å²	102	67.1 Å²	67.1	52%	0.523	32%	0.318	S	S	.	.	H	α-helix	trans	-64.1	-47.3	179.4	-63.1	169.7	0	0	0	110.5	P37 Q38 K39 L43 N44 Q45	P37-I41 PolarHBondContact O-N 3.12Å; Q38-I41 PolarHBondContact O-N 2.87Å; K39-I41 VanDerWaalsContact C-N 3.34Å; K39-I41 PolarHBondContact O-N 2.9Å; I41-L43 PolarHBondContact O-N 3.43Å; I41-N44 WeakPolarHBondContact O-CB 3.39Å; I41-N44 PolarHBondContact O-N 3.14Å; I41-Q45 WeakPolarHBondContact O-CG 3.26Å; I41-Q45 PolarHBondContact O-N 3.37Å
42	Y	98.4	Very high	97.2	Very high	87 Å²	87	67 Å²	67	34%	0.341	32%	0.318	S	S	.	.	H	α-helix	trans	-58.1	-49.3	177.9	168	-99.3	0	0	0	112.1	Q38 K39 N44 Q45 L46 E125	Q38-Y42 WeakPolarHBondContact O-CB 3.39Å; Q38-Y42 PolarHBondContact O-N 3.24Å; K39-Y42 HydrophobicContact CD-CD1 4.27Å; K39-Y42 PolarHBondContact O-N 3.28Å; Y42-N44 PolarHBondContact O-N 2.94Å; Y42-Q45 WeakPolarHBondContact O-CB 3.31Å; Y42-Q45 PolarHBondContact O-N 3.1Å; Y42-Q45 VanDerWaalsContact O-N 3.13Å; Y42-L46 HydrophobicContact CE1-CD2 4.39Å; Y42-L46 PolarHBondContact O-N 3.46Å; Y42-E125 HydrophobicContact CE1-CG 4.28Å; Y42-E125 VanDerWaalsContact CE1-OE1 3.26Å; Y42-E125 WeakPolarHBondContact CE1-OE1 3.49Å
43	L	98.4	Very high	97.3	Very high	0 Å²	0	69.4 Å²	69.4	0%	0	33%	0.331	C	S	.	.	H	α-helix	trans	-66	-31.1	178.7	-67.5	172.7	0	0	0	111.7	K39 I41 L46 L47 E125 V221 L224 R225 Y228	K39-L43 WeakPolarHBondContact O-CB 3.46Å; K39-L43 VanDerWaalsContact O-CG 3.28Å; K39-L43 WeakPolarHBondContact O-CG 3.39Å; K39-L43 PolarHBondContact O-N 3.5Å; I41-L43 PolarHBondContact O-N 3.43Å; L43-L46 HydrophobicContact CD2-CD2 4.26Å; L43-L47 WeakPolarHBondContact O-CB 3.35Å; L43-L47 WeakPolarHBondContact O-CD1 3.42Å; L43-L47 VanDerWaalsContact O-CG 3.29Å; L43-L47 WeakPolarHBondContact O-CG 3.45Å; L43-L47 PolarHBondContact O-N 3.33Å; L43-E125 HydrophobicContact CD2-CB 4.38Å; L43-E125 HydrophobicContact CD2-CG 4Å; L43-V221 HydrophobicContact CD2-CG1 4.19Å; L43-L224 HydrophobicContact CD1-CB 4.02Å; L43-R225 HydrophobicContact CB-CB 3.97Å; L43-R225 HydrophobicContact CB-CG 4.23Å; L43-R225 HydrophobicContact CD1-CB 4.08Å; L43-Y228 HydrophobicContact CD1-CD2 3.68Å; L43-Y228 HydrophobicContact CD1-CE2 3.83Å
44	N	98.1	Very high	97.5	Very high	70 Å²	70	64 Å²	64	37%	0.374	31%	0.313	S	S	.	.	H	α-helix	trans	-64.8	-41.8	172.5	-171.1	73.5	0	0	0	112.2	I40 I41 Y42 L47 Q48 R225	I40-N44 WeakPolarHBondContact O-CB 3.48Å; I40-N44 PolarHBondContact O-N 2.86Å; I41-N44 WeakPolarHBondContact O-CB 3.39Å; I41-N44 PolarHBondContact O-N 3.14Å; Y42-N44 PolarHBondContact O-N 2.94Å; N44-L47 PolarHBondContact O-N 2.94Å; N44-Q48 WeakPolarHBondContact O-CG 3.48Å; N44-R225 PolarHBondContact OD1-NH1 3.43Å
45	Q	98.1	Very high	97.4	Very high	113 Å²	113	62.8 Å²	62.8	53%	0.528	33%	0.332	S	S	.	.	H	α-helix	trans	-65.8	-45.5	174.8	-70.5	170.5	-15.3	0	0	111.2	I41 Y42 L47 Q48	I41-Q45 WeakPolarHBondContact O-CG 3.26Å; I41-Q45 PolarHBondContact O-N 3.37Å; Y42-Q45 WeakPolarHBondContact O-CB 3.31Å; Y42-Q45 PolarHBondContact O-N 3.1Å; Y42-Q45 VanDerWaalsContact O-N 3.13Å; Q45-L47 PolarHBondContact O-N 3.28Å; Q45-Q48 WeakPolarHBondContact O-CA 3.42Å; Q45-Q48 WeakPolarHBondContact O-CB 3.23Å; Q45-Q48 PolarHBondContact O-N 3.36Å
46	L	97.6	Very high	97.3	Very high	12 Å²	12	64.4 Å²	64.4	6%	0.063	34%	0.343	C	S	.	.	H	α-helix	trans	-55.7	-39.8	175.9	-178	60.8	0	0	0	111.5	Y42 L43 Q48 E49 L52 L121 V221	Y42-L46 HydrophobicContact CE1-CD2 4.39Å; Y42-L46 PolarHBondContact O-N 3.46Å; L43-L46 HydrophobicContact CD2-CD2 4.26Å; L46-Q48 PolarHBondContact O-N 3.21Å; L46-E49 HydrophobicContact CD1-CG 4.29Å; L46-E49 VanDerWaalsContact O-CB 3.32Å; L46-E49 WeakPolarHBondContact O-CB 3.47Å; L46-E49 WeakPolarHBondContact O-CG 3.45Å; L46-E49 PolarHBondContact O-N 2.93Å; L46-E49 VanDerWaalsContact O-N 3.13Å; L46-L52 HydrophobicContact CD1-CD1 4.09Å; L46-L52 HydrophobicContact CD2-CD1 4.47Å; L46-L52 HydrophobicContact CG-CD1 3.73Å; L46-L52 VanDerWaalsContact O-CD1 3.29Å; L46-L52 WeakPolarHBondContact O-CD1 3.36Å; L46-L121 HydrophobicContact CD1-CD1 4.29Å; L46-V221 HydrophobicContact CD2-CG1 4.12Å; L46-V221 HydrophobicContact CD2-CG2 4.46Å; L46-V221 HydrophobicContact CG-CG1 4.48Å
47	L	97.9	Very high	97.2	Very high	6 Å²	6	67.3 Å²	67.3	3%	0.031	36%	0.358	C	S	.	.	T	Hydrogen-bonded Turn	trans	-68.2	-10.8	175.3	-75.8	165.2	0	0	0	114.5	L43 N44 Q45 N53 V221 L222 R225	L43-L47 WeakPolarHBondContact O-CB 3.35Å; L43-L47 WeakPolarHBondContact O-CD1 3.42Å; L43-L47 VanDerWaalsContact O-CG 3.29Å; L43-L47 WeakPolarHBondContact O-CG 3.45Å; L43-L47 PolarHBondContact O-N 3.33Å; N44-L47 PolarHBondContact O-N 2.94Å; Q45-L47 PolarHBondContact O-N 3.28Å; L47-N53 PolarHBondContact O-ND2 2.98Å; L47-V221 HydrophobicContact CD1-CG1 4.16Å; L47-V221 HydrophobicContact CD2-CB 3.97Å; L47-V221 HydrophobicContact CD2-CG1 3.71Å; L47-V221 HydrophobicContact CG-CB 4.43Å; L47-V221 HydrophobicContact CG-CG1 3.62Å; L47-L222 HydrophobicContact CD1-CD2 3.65Å; L47-L222 HydrophobicContact CD1-CG 4.3Å; L47-L222 HydrophobicContact CD2-CD2 3.96Å; L47-L222 HydrophobicContact CD2-CG 3.95Å; L47-L222 HydrophobicContact CG-CD2 4.46Å; L47-R225 VanDerWaalsContact CD1-CZ 3.46Å
48	Q	97.7	Very high	97	Very high	128 Å²	128	68.3 Å²	68.3	60%	0.598	36%	0.364	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.3	-12.7	172.2	-56.5	-49.4	-67.1	0	0	112.7	N44 Q45 L46 N53	N44-Q48 WeakPolarHBondContact O-CG 3.48Å; Q45-Q48 WeakPolarHBondContact O-CA 3.42Å; Q45-Q48 WeakPolarHBondContact O-CB 3.23Å; Q45-Q48 PolarHBondContact O-N 3.36Å; L46-Q48 PolarHBondContact O-N 3.21Å; Q48-N53 VanDerWaalsContact C-ND2 3.35Å; Q48-N53 PolarHBondContact O-ND2 3.29Å
49	E	96.9	Very high	96.9	Very high	109 Å²	109	65.8 Å²	65.8	51%	0.509	36%	0.358	S	S	.	.	S	Bend	trans	-63.6	141.6	179.7	-63.5	-65.7	154	0	0	111.3	L46 S51 L52 N53	L46-E49 HydrophobicContact CD1-CG 4.29Å; L46-E49 VanDerWaalsContact O-CB 3.32Å; L46-E49 WeakPolarHBondContact O-CB 3.47Å; L46-E49 WeakPolarHBondContact O-CG 3.45Å; L46-E49 PolarHBondContact O-N 2.93Å; L46-E49 VanDerWaalsContact O-N 3.13Å; E49-S51 PolarHBondContact O-N 2.76Å; E49-S51 VanDerWaalsContact O-N 3.15Å; E49-L52 PolarHBondContact O-N 3.43Å; E49-N53 PolarHBondContact O-N 3.16Å; E49-N53 PolarHBondContact O-ND2 3.46Å
50	D	96.4	Very high	96.7	Very high	142 Å²	142	64.5 Å²	64.5	76%	0.759	35%	0.353	S	S	*	.	G	3₁₀ helix	trans	-57.6	-32.9	-179.1	-70	-22.2	0	0	0	111.9	L52 N53	D50-L52 PolarHBondContact O-N 3.35Å; D50-L52 VanDerWaalsContact O-N 3.16Å; D50-N53 CarbonylContact O-C 3.54Å; D50-N53 PolarHBondContact O-N 3.45Å
51	S	95.4	Very high	96.5	Very high	50 Å²	50	68.5 Å²	68.5	35%	0.35	37%	0.365	S	S	.	.	G	3₁₀ helix	trans	-61.7	-22.4	177.6	60.6	0	0	0	0	113.5	E49 L118 Y214	E49-S51 PolarHBondContact O-N 2.76Å; E49-S51 VanDerWaalsContact O-N 3.15Å; S51-L118 WeakPolarHBondContact O-CD2 3.28Å; S51-Y214 WeakPolarHBondContact O-CE2 3.48Å
52	L	96.7	Very high	96.4	Very high	1 Å²	1	64.4 Å²	64.4	1%	0.005	35%	0.346	C	S	.	.	G	3₁₀ helix	trans	-107.4	3.7	177.2	-78.6	165	0	0	0	112.9	L46 E49 D50 L118 Y214 R218 V221	L46-L52 HydrophobicContact CD1-CD1 4.09Å; L46-L52 HydrophobicContact CD2-CD1 4.47Å; L46-L52 HydrophobicContact CG-CD1 3.73Å; L46-L52 VanDerWaalsContact O-CD1 3.29Å; L46-L52 WeakPolarHBondContact O-CD1 3.36Å; E49-L52 PolarHBondContact O-N 3.43Å; D50-L52 PolarHBondContact O-N 3.35Å; D50-L52 VanDerWaalsContact O-N 3.16Å; L52-L118 HydrophobicContact CD2-CD2 3.99Å; L52-L118 HydrophobicContact CG-CD2 3.92Å; L52-Y214 PolarHBondContact O-OH 3.39Å; L52-R218 HydrophobicContact CD2-CB 4.04Å; L52-R218 HydrophobicContact CD2-CG 4.18Å; L52-R218 VanDerWaalsContact O-CD 3.22Å; L52-R218 WeakPolarHBondContact O-CD 3.34Å; L52-R218 PolarHBondContact O-NE 2.92Å; L52-V221 HydrophobicContact CD1-CG2 4.33Å
53	N	96.9	Very high	96.1	Very high	68 Å²	68	64.4 Å²	64.4	36%	0.364	36%	0.357	S	S	.	.			trans	-126.6	38.9	-180	-65.6	-64.2	0	0	0	112.2	L47 Q48 E49 D50 A55 Y214	L47-N53 PolarHBondContact O-ND2 2.98Å; Q48-N53 VanDerWaalsContact C-ND2 3.35Å; Q48-N53 PolarHBondContact O-ND2 3.29Å; E49-N53 PolarHBondContact O-N 3.16Å; E49-N53 PolarHBondContact O-ND2 3.46Å; D50-N53 CarbonylContact O-C 3.54Å; D50-N53 PolarHBondContact O-N 3.45Å; N53-A55 PolarHBondContact O-N 3.43Å; N53-Y214 PolarHBondContact N-OH 3.48Å
54	V	96.5	Very high	95.9	Very high	35 Å²	35	65.5 Å²	65.5	21%	0.212	36%	0.363	C	S	.	.			trans	-66.7	115.3	174.2	-176.7	0	0	0	0	109.9	D56 S59 L60 Y214	V54-D56 VanDerWaalsContact CG1-O 3.22Å; V54-D56 WeakPolarHBondContact CG1-O 3.26Å; V54-S59 VanDerWaalsContact CG1-OG 3.28Å; V54-S59 WeakPolarHBondContact CG1-OG 3.29Å; V54-L60 HydrophobicContact CG1-CG 4.34Å; V54-L60 HydrophobicContact CG2-CD2 4.29Å; V54-Y214 HydrophobicContact CB-CE1 4.35Å; V54-Y214 HydrophobicContact CB-CE2 4.14Å; V54-Y214 WeakPolarHBondContact CB-OH 3.36Å; V54-Y214 HydrophobicContact CG2-CE2 3.81Å; V54-Y214 PolarHBondContact N-OH 3.05Å
55	A	94.8	Very high	95.6	Very high	109 Å²	109	68 Å²	68	90%	0.901	38%	0.376	S	S	*	.	S	Bend	trans	-76.8	-40.2	180	0	0	0	0	0	112.9	N53	N53-A55 PolarHBondContact O-N 3.43Å
56	D	95.9	Very high	95.3	Very high	91 Å²	91	62.9 Å²	62.9	49%	0.487	35%	0.352	S	S	.	.			trans	-110.9	107.7	178.1	178.3	6.9	0	0	0	110.1	V54 T58 S59	V54-D56 VanDerWaalsContact CG1-O 3.22Å; V54-D56 WeakPolarHBondContact CG1-O 3.26Å; D56-T58 PolarHBondContact O-N 2.89Å; D56-T58 WeakPolarHBondContact OD1-CB 3.42Å; D56-T58 WeakPolarHBondContact OD1-CG2 3.49Å; D56-T58 PolarHBondContact OD1-N 3.48Å; D56-T58 PolarHBondContact OD1-OG1 3.05Å; D56-T58 PolarHBondContact OD2-OG1 3.3Å; D56-S59 VanDerWaalsContact O-CB 3.3Å; D56-S59 WeakPolarHBondContact O-CB 3.41Å; D56-S59 PolarHBondContact O-N 3.49Å; D56-S59 VanDerWaalsContact O-N 3.15Å; D56-S59 PolarHBondContact O-OG 3.05Å
57	L	95	Very high	94.9	Very high	61 Å²	61	64.3 Å²	64.3	32%	0.319	36%	0.362	S	S	.	.	G	3₁₀ helix	trans	-66.3	-20.6	-178.3	-58.2	-173.4	0	0	0	112.7	S59 L60 E211 Y214	L57-S59 PolarHBondContact O-N 3.34Å; L57-S59 VanDerWaalsContact O-N 3.16Å; L57-L60 HydrophobicContact CB-CD1 4.34Å; L57-L60 HydrophobicContact CD2-CD1 3.89Å; L57-L60 VanDerWaalsContact O-CB 3.23Å; L57-L60 WeakPolarHBondContact O-CB 3.48Å; L57-L60 PolarHBondContact O-N 3.27Å; L57-E211 HydrophobicContact CB-CG 4.06Å; L57-E211 HydrophobicContact CD1-CB 4.46Å; L57-Y214 HydrophobicContact CD2-CD1 3.52Å; L57-Y214 HydrophobicContact CD2-CE1 3.49Å; L57-Y214 VanDerWaalsContact CD2-CE1 3.49Å
58	T	93.8	Very high	94.5	Very high	65 Å²	65	69.3 Å²	69.3	40%	0.399	39%	0.388	S	S	.	.	G	3₁₀ helix	trans	-63.6	-24.1	175.8	72	0	0	0	0	111.9	D56 L60 R61	D56-T58 PolarHBondContact O-N 2.89Å; D56-T58 WeakPolarHBondContact OD1-CB 3.42Å; D56-T58 WeakPolarHBondContact OD1-CG2 3.49Å; D56-T58 PolarHBondContact OD1-N 3.48Å; D56-T58 PolarHBondContact OD1-OG1 3.05Å; D56-T58 PolarHBondContact OD2-OG1 3.3Å; T58-L60 PolarHBondContact O-N 3.4Å; T58-R61 WeakPolarHBondContact O-CB 3.44Å; T58-R61 WeakPolarHBondContact O-CG 3.34Å; T58-R61 PolarHBondContact O-N 3.5Å; T58-R61 VanDerWaalsContact O-N 3.11Å
59	S	95.4	Very high	93.9	Very high	54 Å²	54	65.2 Å²	65.2	38%	0.378	37%	0.372	S	S	.	.	G	3₁₀ helix	trans	-64.5	-18.2	172.8	75.4	0	0	0	0	113.3	V54 D56 L57 R61 K114	V54-S59 VanDerWaalsContact CG1-OG 3.28Å; V54-S59 WeakPolarHBondContact CG1-OG 3.29Å; D56-S59 VanDerWaalsContact O-CB 3.3Å; D56-S59 WeakPolarHBondContact O-CB 3.41Å; D56-S59 PolarHBondContact O-N 3.49Å; D56-S59 VanDerWaalsContact O-N 3.15Å; D56-S59 PolarHBondContact O-OG 3.05Å; L57-S59 PolarHBondContact O-N 3.34Å; L57-S59 VanDerWaalsContact O-N 3.16Å; S59-R61 VanDerWaalsContact C-N 3.3Å; S59-K114 PolarHBondContact O-NZ 3.38Å
60	L	95.1	Very high	93.3	Very high	6 Å²	6	67 Å²	67	3%	0.031	39%	0.385	C	S	.	.	G	3₁₀ helix	trans	-79.3	-12.8	176.3	-61.7	167.9	0	0	0	112.7	V54 L57 T58 A62 N112 K114 Y214	V54-L60 HydrophobicContact CG1-CG 4.34Å; V54-L60 HydrophobicContact CG2-CD2 4.29Å; L57-L60 HydrophobicContact CB-CD1 4.34Å; L57-L60 HydrophobicContact CD2-CD1 3.89Å; L57-L60 VanDerWaalsContact O-CB 3.23Å; L57-L60 WeakPolarHBondContact O-CB 3.48Å; L57-L60 PolarHBondContact O-N 3.27Å; T58-L60 PolarHBondContact O-N 3.4Å; L60-A62 PolarHBondContact O-N 3.29Å; L60-A62 VanDerWaalsContact O-N 3.11Å; L60-N112 PolarHBondContact O-ND2 3.31Å; L60-K114 HydrophobicContact CD2-CB 4.29Å; L60-K114 HydrophobicContact CD2-CD 4.2Å; L60-Y214 HydrophobicContact CD1-CD1 3.77Å; L60-Y214 HydrophobicContact CD1-CD2 3.81Å; L60-Y214 HydrophobicContact CD1-CE1 4.46Å; L60-Y214 HydrophobicContact CD1-CG 3.4Å; L60-Y214 HydrophobicContact CD2-CD2 4.16Å
61	R	94.3	Very high	92.7	Very high	130 Å²	130	65.5 Å²	65.5	49%	0.491	38%	0.383	S	S	.	.			trans	-64.5	115.1	-175.3	-67.5	-178	179.8	-176.9	-0.6	111	T58 S59 H207 E211	T58-R61 WeakPolarHBondContact O-CB 3.44Å; T58-R61 WeakPolarHBondContact O-CG 3.34Å; T58-R61 PolarHBondContact O-N 3.5Å; T58-R61 VanDerWaalsContact O-N 3.11Å; S59-R61 VanDerWaalsContact C-N 3.3Å; R61-H207 HydrophobicContact CG-CB 4.12Å; R61-E211 IonicContact CZ-OE1 4Å; R61-E211 IonicContact NE-OE1 3.57Å; R61-E211 PolarHBondContact NE-OE1 2.9Å; R61-E211 IonicContact NH2-OE1 2.63Å; R61-E211 PolarHBondContact NH2-OE1 2.74Å; R61-E211 VanDerWaalsContact NH2-OE1 3.09Å
62	A	94.3	Very high	92.1	Very high	15 Å²	15	68.3 Å²	68.3	12%	0.124	40%	0.4	C	S	.	.			trans	-75.4	147.8	170.1	0	0	0	0	0	110.4	L60 L64 N112 H207	L60-A62 PolarHBondContact O-N 3.29Å; L60-A62 VanDerWaalsContact O-N 3.11Å; A62-L64 PolarHBondContact O-N 2.81Å; A62-N112 HydrophobicContact CB-CB 4.13Å; A62-H207 PolarHBondContact O-CE1 3.39Å
63	P	93.6	Very high	91.2	Very high	87 Å²	87	73.2 Å²	73.2	57%	0.565	43%	0.432	S	S	*	.			trans	-60.8	136.9	174.9	25.9	-33.4	0	0	0	110.8
64	L	93.7	Very high	90.1	Very high	24 Å²	24	79 Å²	79	13%	0.126	45%	0.454	C	S	.	.			trans	-123.9	80.5	179.3	-170.7	65.3	0	0	0	109.5	A62 I66 L109 R203 V206	A62-L64 PolarHBondContact O-N 2.81Å; L64-I66 HydrophobicContact CD1-CD1 3.79Å; L64-I66 HydrophobicContact CD1-CG1 4.19Å; L64-I66 HydrophobicContact CD2-CD1 4Å; L64-I66 HydrophobicContact CG-CD1 3.71Å; L64-I66 HydrophobicContact CG-CG1 4.03Å; L64-I66 PolarHBondContact O-N 2.93Å; L64-L109 HydrophobicContact CD1-CD1 4.3Å; L64-L109 HydrophobicContact CD1-CD2 4.45Å; L64-R203 HydrophobicContact CD2-CB 3.92Å; L64-R203 HydrophobicContact CD2-CG 3.97Å; L64-V206 HydrophobicContact CD1-CG1 4.38Å; L64-V206 HydrophobicContact CD2-CB 4.07Å; L64-V206 HydrophobicContact CD2-CG1 4.26Å; L64-V206 HydrophobicContact CD2-CG2 4.17Å
65	D	91.8	Very high	88.3	Confident	121 Å²	121	85 Å²	85	65%	0.647	49%	0.485	S	S	*	.			trans	-78.1	53.2	-170.5	-60.1	-32.3	0	0	0	112.9
66	I	91.1	Very high	86.3	Confident	7 Å²	7	86.8 Å²	86.8	4%	0.036	48%	0.48	C	S	.	.	P	Polyproline II helix	trans	-89.9	125.7	174.4	-58.1	171.5	0	0	0	108.3	L64 I68 L109 A193 T197 R203	L64-I66 HydrophobicContact CD1-CD1 3.79Å; L64-I66 HydrophobicContact CD1-CG1 4.19Å; L64-I66 HydrophobicContact CD2-CD1 4Å; L64-I66 HydrophobicContact CG-CD1 3.71Å; L64-I66 HydrophobicContact CG-CG1 4.03Å; L64-I66 PolarHBondContact O-N 2.93Å; I66-I68 PolarHBondContact O-N 3.19Å; I66-L109 HydrophobicContact CD1-CD1 3.94Å; I66-L109 HydrophobicContact CG1-CD1 3.74Å; I66-L109 HydrophobicContact CG1-CD2 4.02Å; I66-A193 HydrophobicContact CD1-CB 3.53Å; I66-T197 HydrophobicContact CG2-CG2 3.73Å; I66-R203 VanDerWaalsContact O-CZ 3.25Å; I66-R203 PolarHBondContact O-NH1 3.36Å; I66-R203 PolarHBondContact O-NH2 2.77Å
67	P	89.9	Confident	84.1	Confident	41 Å²	41	90.6 Å²	90.6	27%	0.266	49%	0.494	S	S	.	.	P	Polyproline II helix	trans	-56	135	176.8	-25.4	34.9	0	0	0	112.3	P104 R203	P67-P104 HydrophobicContact CB-CB 3.81Å; P67-P104 HydrophobicContact CB-CG 3.87Å; P67-P104 HydrophobicContact CG-CB 3.86Å; P67-P104 HydrophobicContact CG-CG 4.47Å; P67-R203 PolarHBondContact O-NH2 3.45Å; P67-R203 VanDerWaalsContact O-NH2 3.08Å
68	I	88.5	Confident	81.7	Confident	112 Å²	112	96.8 Å²	96.8	57%	0.574	52%	0.524	S	S	*	.	P	Polyproline II helix	trans	-91	126.3	175.9	-60	174	0	0	0	108	I66 M200	I66-I68 PolarHBondContact O-N 3.19Å; I68-M200 HydrophobicContact CD1-CE 4.35Å
69	P	85.7	Confident	79.2	Confident	42 Å²	42	101.3 Å²	101.3	27%	0.273	54%	0.54	S	S	.	.	P	Polyproline II helix	trans	-66	140.9	177.2	-21	34	0	0	0	112	T197 H198	P69-T197 WeakPolarHBondContact CD-O 3.18Å; P69-T197 WeakPolarHBondContact CG-OG1 3.4Å; P69-H198 HydrophobicContact CG-CB 4.32Å
70	D	85.2	Confident	76.8	Confident	145 Å²	145	104.9 Å²	104.9	78%	0.775	56%	0.56	S	S	*	*	P	Polyproline II helix	trans	-68.6	145.7	169.4	-67.4	-44.6	0	0	0	110.5
71	P	83.9	Confident	74.2	Confident	111 Å²	111	112.2 Å²	112.2	72%	0.721	60%	0.599	S	S	*	*	P	Polyproline II helix	trans	-59.4	143.6	173.3	25.1	-32.6	0	0	0	109.9
72	P	81	Confident	71.7	Confident	110 Å²	110	115.1 Å²	115.1	71%	0.714	62%	0.616	S	S	*	*	P	Polyproline II helix	trans	-58.6	149.3	174.7	25.4	-32.7	0	0	0	110	K74	P72-K74 PolarHBondContact O-N 3.39Å
73	P	79	Confident	69	Low	104 Å²	104	123.7 Å²	123.7	68%	0.675	65%	0.653	S	S	*	*	P	Polyproline II helix	trans	-52.9	136.3	172.2	-18.5	29.2	0	0	0	109.3	D75	P73-D75 PolarHBondContact O-N 3.23Å
74	K	73.4	Confident	66.2	Low	188 Å²	188	127.1 Å²	127.1	82%	0.817	66%	0.662	S	S	*	*	P	Polyproline II helix	trans	-66.6	123.5	167.9	-68	-178.4	179.8	179.5	0	106.6	P72 D76	P72-K74 PolarHBondContact O-N 3.39Å; K74-D76 VanDerWaalsContact C-N 3.27Å; K74-D76 PolarHBondContact O-N 2.91Å
75	D	59.9	Low	63.6	Low	163 Å²	163	134.5 Å²	134.5	87%	0.872	69%	0.693	S	S	*	*			trans	-64.8	96	166.3	-74	-32.7	0	0	0	106.7	P73 E77	P73-D75 PolarHBondContact O-N 3.23Å; D75-E77 PolarHBondContact O-N 3.02Å; D75-E77 VanDerWaalsContact O-N 3.15Å
76	D	51.9	Low	60.9	Low	146 Å²	146	138.4 Å²	138.4	78%	0.781	70%	0.704	S	S	*	*			trans	-61.8	115.5	166.1	-72.9	-28.9	0	0	0	106.8	K74 M78	K74-D76 VanDerWaalsContact C-N 3.27Å; K74-D76 PolarHBondContact O-N 2.91Å; D76-M78 PolarHBondContact O-N 2.67Å
77	E	50.1	Low	58.4	Low	170 Å²	170	147.7 Å²	147.7	79%	0.794	75%	0.747	S	S	*	*			trans	-3.4	102.8	169.7	-63.9	173.4	170	0	0	114.3	D75 E79	D75-E77 PolarHBondContact O-N 3.02Å; D75-E77 VanDerWaalsContact O-N 3.15Å; E77-E79 PolarHBondContact O-N 3.39Å
78	M	44.1	Very low	55.7	Low	191 Å²	191	149.4 Å²	149.4	94%	0.941	77%	0.772	S	S	*	*			trans	-65.8	90.2	161	-85.8	-170.4	-178.3	0	0	108.1	D76 T80	D76-M78 PolarHBondContact O-N 2.67Å; M78-T80 PolarHBondContact O-N 2.88Å; M78-T80 VanDerWaalsContact O-N 3.13Å
79	E	42.2	Very low	53.5	Low	160 Å²	160	154.1 Å²	154.1	75%	0.748	79%	0.789	S	S	*	*			trans	-42.9	115.8	158.3	-85.1	-70.7	158.4	0	0	108.9	E77 D81	E77-E79 PolarHBondContact O-N 3.39Å; E79-D81 PolarHBondContact O-N 3.01Å
80	T	44.3	Very low	51	Low	129 Å²	129	163.9 Å²	163.9	79%	0.791	82%	0.82	S	S	*	*			trans	-62.6	111.3	168.4	42.3	0	0	0	0	108.4	M78	M78-T80 PolarHBondContact O-N 2.88Å; M78-T80 VanDerWaalsContact O-N 3.13Å
81	D	39.9	Very low	49.2	Very low	160 Å²	160	164.1 Å²	164.1	86%	0.856	82%	0.821	S	S	*	*			trans	-130.4	125.8	157.3	-141.9	-3.8	0	0	0	112.8	E79	E79-D81 PolarHBondContact O-N 3.01Å
82	K	43	Very low	47	Very low	192 Å²	192	168.4 Å²	168.4	84%	0.835	83%	0.829	S	S	*	*			trans	-82.6	129.7	177.7	-73.5	171.3	173.4	172	0	107.8
83	Q	35.9	Very low	45.4	Very low	194 Å²	194	174.3 Å²	174.3	91%	0.907	84%	0.837	S	S	*	*			trans	-165.1	127.1	138	-111.1	164.9	15.5	0	0	115.5
84	E	36.8	Very low	43.6	Very low	160 Å²	160	179.6 Å²	179.6	75%	0.748	85%	0.849	S	S	*	*			trans	-9	141.7	162.8	-57.7	-170.3	135.5	0	0	124.2
85	K	38	Very low	41.7	Very low	178 Å²	178	174.3 Å²	174.3	77%	0.774	85%	0.848	S	S	*	*			trans	53.7	118.6	135.5	-71.5	178.1	175.4	164.3	0	120.8
86	K	34.2	Very low	41	Very low	204 Å²	204	173.8 Å²	173.8	89%	0.887	84%	0.844	S	S	*	*				169	145.1	105	-97	177	179.6	174.1	0	112.9
87	E	40.4	Very low	40.3	Very low	202 Å²	202	174.3 Å²	174.3	94%	0.944	85%	0.847	S	S	*	*			trans	-60.5	150.6	173.3	-62.7	173.3	132.8	0	0	113.7
88	G	31.6	Very low	39.9	Very low	77 Å²	77	170.1 Å²	170.1	79%	0.794	83%	0.834	S	S	*	*			trans	165.9	109.8	162.7	0	0	0	0	0	114.9	R90	G88-R90 PolarHBondContact O-N 3.39Å
89	K	43	Very low	39.8	Very low	210 Å²	210	167.8 Å²	167.8	91%	0.913	83%	0.825	S	S	*	*			trans	-47.7	130.4	167.2	-87.5	173.3	169.6	172.1	0	112.1
90	R	33.7	Very low	39.9	Very low	247 Å²	247	167.8 Å²	167.8	93%	0.932	82%	0.823	S	S	*	*			trans	-168.5	123.2	137.1	-109.1	166	-177.2	-179.2	1.1	112.4	G88	G88-R90 PolarHBondContact O-N 3.39Å
91	D	46.5	Very low	39.9	Very low	151 Å²	151	168.1 Å²	168.1	81%	0.807	82%	0.819	S	S	*	*			trans	-49.4	124.1	166.6	-169.2	4.8	0	0	0	112.1
92	K	37.8	Very low	40.2	Very low	200 Å²	200	166 Å²	166	87%	0.87	81%	0.812	S	S	*	*			trans	-157.4	106.2	158.5	-95.1	-174	-173.5	175.6	0	109.8	K94	K92-K94 PolarHBondContact O-N 2.99Å
93	R	48	Very low	40.8	Very low	234 Å²	234	160.5 Å²	160.5	88%	0.883	79%	0.794	S	S	*	*			trans	-43.5	122.1	152.6	-74.5	173.3	172.1	169.8	-3.2	110
94	K	41.4	Very low	41.9	Very low	216 Å²	216	154.5 Å²	154.5	94%	0.939	77%	0.773	S	S	*	*			trans	169.4	119.5	140.9	-96.9	171.6	-177.2	-170.6	0	109.2	K92	K92-K94 PolarHBondContact O-N 2.99Å
95	G	33.3	Very low	43.6	Very low	77 Å²	77	156.7 Å²	156.7	79%	0.794	78%	0.78	S	S	*	*			trans	162.4	47.4	176.8	0	0	0	0	0	111.5	N97	G95-N97 PolarHBondContact O-N 3.24Å
96	L	45.2	Very low	45.8	Very low	152 Å²	152	150.4 Å²	150.4	80%	0.796	76%	0.758	S	S	*	*			trans	-61.9	117.6	160	-138.7	79.9	0	0	0	105.7
97	N	38	Very low	48.3	Very low	156 Å²	156	143.3 Å²	143.3	83%	0.834	74%	0.742	S	S	*	*			trans	-160.8	73.7	144.7	-92	-12.9	0	0	0	106.8	G95 L99	G95-N97 PolarHBondContact O-N 3.24Å; N97-L99 PolarHBondContact O-N 3.5Å
98	P	40.4	Very low	50.8	Low	82 Å²	82	142.4 Å²	142.4	53%	0.532	74%	0.736	S	S	.	*			trans	-70.5	100.7	151.5	34.6	-27.1	0	0	0	103.9	F100	P98-F100 HydrophobicContact CB-CD2 3.74Å; P98-F100 HydrophobicContact CB-CE2 4.12Å; P98-F100 HydrophobicContact CG-CD2 4.19Å; P98-F100 PolarHBondContact O-N 3.47Å
99	L	42.8	Very low	53.8	Low	143 Å²	143	140.5 Å²	140.5	75%	0.749	71%	0.707	S	S	*	*			trans	-62.5	66.9	159.9	-174	69.6	0	0	0	106.6	N97 L101	N97-L99 PolarHBondContact O-N 3.5Å; L99-L101 VanDerWaalsContact C-N 3.31Å; L99-L101 PolarHBondContact O-N 3.28Å
100	F	43.4	Very low	56.3	Low	160 Å²	160	132.9 Å²	132.9	70%	0.702	68%	0.679	S	S	*	*			trans	-61.1	107.7	156.1	-95.4	-86.4	0	0	0	102.9	P98 T102	P98-F100 HydrophobicContact CB-CD2 3.74Å; P98-F100 HydrophobicContact CB-CE2 4.12Å; P98-F100 HydrophobicContact CG-CD2 4.19Å; P98-F100 PolarHBondContact O-N 3.47Å; F100-T102 HydrophobicContact CB-CG2 4.26Å; F100-T102 PolarHBondContact O-N 3.02Å
101	L	44.5	Very low	59.3	Low	135 Å²	135	122.6 Å²	122.6	71%	0.707	65%	0.65	S	S	*	*			trans	-51.7	89.4	150.8	-82.8	91.4	0	0	0	105.6	L99 V103	L99-L101 VanDerWaalsContact C-N 3.31Å; L99-L101 PolarHBondContact O-N 3.28Å; L101-V103 PolarHBondContact O-N 3.13Å
102	T	46.3	Very low	61.7	Low	116 Å²	116	115.5 Å²	115.5	71%	0.712	61%	0.612	S	S	*	*			trans	-70.3	88.3	169.2	47.4	0	0	0	0	104.5	F100 P104	F100-T102 HydrophobicContact CB-CG2 4.26Å; F100-T102 PolarHBondContact O-N 3.02Å; T102-P104 VanDerWaalsContact O-CD 3.24Å; T102-P104 WeakPolarHBondContact O-CD 3.34Å
103	V	55.1	Low	64.6	Low	76 Å²	76	111.9 Å²	111.9	46%	0.461	60%	0.598	S	S	.	*			trans	-49.4	115.2	167.7	-175.7	0	0	0	0	105	L101 K105 T197	L101-V103 PolarHBondContact O-N 3.13Å; V103-K105 PolarHBondContact O-N 3.11Å; V103-T197 HydrophobicContact CG1-CG2 3.94Å
104	P	58.7	Low	66.9	Low	69 Å²	69	106 Å²	106	45%	0.448	58%	0.579	S	S	.	*	P	Polyproline II helix	trans	-57	129.6	-174.6	-21.7	30.8	0	0	0	108.1	P67 T102 C106	P67-P104 HydrophobicContact CB-CB 3.81Å; P67-P104 HydrophobicContact CB-CG 3.87Å; P67-P104 HydrophobicContact CG-CB 3.86Å; P67-P104 HydrophobicContact CG-CG 4.47Å; T102-P104 VanDerWaalsContact O-CD 3.24Å; T102-P104 WeakPolarHBondContact O-CD 3.34Å; P104-C106 PolarHBondContact O-N 3.46Å
105	K	73.5	Confident	69.6	Low	206 Å²	206	95.7 Å²	95.7	90%	0.896	53%	0.534	S	S	*	.	P	Polyproline II helix	trans	-55.9	119.1	-178	-76.8	-176.6	176.9	179.6	0	108.4	V103	V103-K105 PolarHBondContact O-N 3.11Å
106	C	83.8	Confident	72.7	Confident	46 Å²	46	94.6 Å²	94.6	31%	0.311	51%	0.51	S	S	.	.	P	Polyproline II helix	trans	-63.3	135.3	178.8	-171.1	0	0	0	0	109.8	P104	P104-C106 PolarHBondContact O-N 3.46Å
107	G	88	Confident	75.2	Confident	55 Å²	55	90.7 Å²	90.7	57%	0.567	50%	0.495	S	S	*	.			trans	-75.5	-170	176.6	0	0	0	0	0	112.8	L109	G107-L109 PolarHBondContact O-N 3.36Å
108	F	92.1	Very high	78.1	Confident	183 Å²	183	83.5 Å²	83.5	80%	0.803	46%	0.457	S	S	*	.			trans	-68.1	128.7	172.2	174.7	-105.6	0	0	0	110.4	P110	F108-P110 HydrophobicContact CE1-CB 3.95Å; F108-P110 HydrophobicContact CZ-CB 4.5Å
109	L	94.5	Very high	80.8	Confident	36 Å²	36	79.8 Å²	79.8	19%	0.188	43%	0.432	C	S	.	.			trans	-111.3	112.2	177.7	-60.1	177.2	0	0	0	109.5	L64 I66 G107 V190	L64-L109 HydrophobicContact CD1-CD1 4.3Å; L64-L109 HydrophobicContact CD1-CD2 4.45Å; I66-L109 HydrophobicContact CD1-CD1 3.94Å; I66-L109 HydrophobicContact CG1-CD1 3.74Å; I66-L109 HydrophobicContact CG1-CD2 4.02Å; G107-L109 PolarHBondContact O-N 3.36Å; L109-V190 HydrophobicContact CB-CG1 4.21Å; L109-V190 HydrophobicContact CD1-CG1 3.49Å; L109-V190 VanDerWaalsContact CD1-CG1 3.49Å
110	P	95.6	Very high	83.4	Confident	50 Å²	50	75.8 Å²	75.8	33%	0.325	42%	0.42	S	S	.	.			trans	-75.5	168.6	-178	30	-34.4	0	0	0	113.8	F108 R186	F108-P110 HydrophobicContact CE1-CB 3.95Å; F108-P110 HydrophobicContact CZ-CB 4.5Å; P110-R186 PolarHBondContact O-NH1 2.82Å
111	G	96	Very high	86	Confident	31 Å²	31	71.4 Å²	71.4	32%	0.32	40%	0.404	S	S	.	.			trans	-70.4	170.7	167.3	0	0	0	0	0	112.4	E113	G111-E113 PolarHBondContact O-N 3.29Å
112	N	98.1	Very high	88.6	Confident	3 Å²	3	65 Å²	65	2%	0.016	37%	0.37	C	S	.	.			trans	-84.3	101.5	172.2	-171.3	-42.5	0	0	0	110.3	L60 A62 K114 V115 L116 D210	L60-N112 PolarHBondContact O-ND2 3.31Å; A62-N112 HydrophobicContact CB-CB 4.13Å; N112-K114 PolarHBondContact O-N 3.43Å; N112-K114 PolarHBondContact OD1-N 3.43Å; N112-K114 VanDerWaalsContact OD1-N 3.12Å; N112-V115 HydrophobicContact CB-CB 4.12Å; N112-V115 HydrophobicContact CB-CG2 4.09Å; N112-V115 PolarHBondContact O-N 3.24Å; N112-V115 VanDerWaalsContact O-N 3.17Å; N112-V115 PolarHBondContact OD1-N 3.32Å; N112-L116 VanDerWaalsContact O-CG 3.28Å; N112-L116 WeakPolarHBondContact O-CG 3.5Å; N112-L116 PolarHBondContact O-N 2.95Å; N112-D210 WeakPolarHBondContact ND2-CB 3.43Å; N112-D210 PolarHBondContact ND2-OD2 3.45Å
113	E	97.8	Very high	91.1	Very high	124 Å²	124	63.2 Å²	63.2	58%	0.579	35%	0.352	S	S	*	.	H	α-helix	trans	-58.5	-32.2	-176.1	-65.7	-56.6	142.9	0	0	114	G111 S117	G111-E113 PolarHBondContact O-N 3.29Å; E113-S117 WeakPolarHBondContact O-CB 3.24Å; E113-S117 PolarHBondContact O-N 2.95Å; E113-S117 PolarHBondContact O-OG 3.1Å
114	K	97.3	Very high	93.1	Very high	109 Å²	109	62.6 Å²	62.6	47%	0.474	35%	0.35	S	S	.	.	H	α-helix	trans	-69	-46	177.9	-65.1	-177.4	178.1	-176.1	0	110.9	S59 L60 N112 S117 L118	S59-K114 PolarHBondContact O-NZ 3.38Å; L60-K114 HydrophobicContact CD2-CB 4.29Å; L60-K114 HydrophobicContact CD2-CD 4.2Å; N112-K114 PolarHBondContact O-N 3.43Å; N112-K114 PolarHBondContact OD1-N 3.43Å; N112-K114 VanDerWaalsContact OD1-N 3.12Å; K114-S117 PolarHBondContact O-N 2.99Å; K114-L118 PolarHBondContact O-N 2.84Å; K114-L118 VanDerWaalsContact O-N 3.08Å
115	V	97.9	Very high	95	Very high	0 Å²	0	59.9 Å²	59.9	0%	0	33%	0.331	C	S	.	.	H	α-helix	trans	-66.1	-40.1	175.9	-179.7	0	0	0	0	110.7	N112 S117 L118 L119 Y182 D210 A213 L217	N112-V115 HydrophobicContact CB-CB 4.12Å; N112-V115 HydrophobicContact CB-CG2 4.09Å; N112-V115 PolarHBondContact O-N 3.24Å; N112-V115 VanDerWaalsContact O-N 3.17Å; N112-V115 PolarHBondContact OD1-N 3.32Å; V115-S117 VanDerWaalsContact C-N 3.35Å; V115-S117 PolarHBondContact O-N 3.05Å; V115-L118 PolarHBondContact O-N 2.97Å; V115-L119 HydrophobicContact CG1-CD1 3.94Å; V115-L119 HydrophobicContact CG1-CG 4.41Å; V115-L119 WeakPolarHBondContact O-CB 3.35Å; V115-L119 WeakPolarHBondContact O-CG 3.37Å; V115-L119 PolarHBondContact O-N 3.05Å; V115-Y182 HydrophobicContact CG1-CD1 4.49Å; V115-Y182 HydrophobicContact CG1-CE1 3.72Å; V115-Y182 HydrophobicContact CG1-CE2 4.21Å; V115-D210 HydrophobicContact CG2-CB 4.31Å; V115-A213 HydrophobicContact CG1-CB 4.15Å; V115-L217 HydrophobicContact CG1-CD1 4.08Å
116	L	98.2	Very high	96.2	Very high	54 Å²	54	50.1 Å²	50.1	28%	0.283	29%	0.289	S	S	.	.	H	α-helix	trans	-62.3	-40.5	176.1	-69.7	175.8	0	0	0	112.4	N112 L119 A120 F183	N112-L116 VanDerWaalsContact O-CG 3.28Å; N112-L116 WeakPolarHBondContact O-CG 3.5Å; N112-L116 PolarHBondContact O-N 2.95Å; L116-L119 HydrophobicContact CD2-CD1 4.37Å; L116-L119 WeakPolarHBondContact O-CB 3.36Å; L116-L119 PolarHBondContact O-N 2.92Å; L116-A120 PolarHBondContact O-N 2.77Å; L116-F183 HydrophobicContact CD2-CE1 3.73Å; L116-F183 HydrophobicContact CD2-CZ 4.22Å
117	S	97.6	Very high	97	Very high	71 Å²	71	55.1 Å²	55.1	50%	0.497	30%	0.301	S	S	.	.	H	α-helix	trans	-63.4	-43.8	175.6	-61.3	0	0	0	0	111.3	E113 K114 V115 A120 L121	E113-S117 WeakPolarHBondContact O-CB 3.24Å; E113-S117 PolarHBondContact O-N 2.95Å; E113-S117 PolarHBondContact O-OG 3.1Å; K114-S117 PolarHBondContact O-N 2.99Å; V115-S117 VanDerWaalsContact C-N 3.35Å; V115-S117 PolarHBondContact O-N 3.05Å; S117-A120 WeakPolarHBondContact O-CB 3.42Å; S117-A120 PolarHBondContact O-N 3.26Å; S117-L121 PolarHBondContact O-N 3.5Å
118	L	97.8	Very high	97.5	Very high	5 Å²	5	54 Å²	54	3%	0.026	28%	0.284	C	S	.	.	H	α-helix	trans	-63.8	-43.2	174.3	-75.7	173.3	0	0	0	112.4	S51 L52 K114 V115 A120 L121 V122 Y214 L217	S51-L118 WeakPolarHBondContact O-CD2 3.28Å; L52-L118 HydrophobicContact CD2-CD2 3.99Å; L52-L118 HydrophobicContact CG-CD2 3.92Å; K114-L118 PolarHBondContact O-N 2.84Å; K114-L118 VanDerWaalsContact O-N 3.08Å; V115-L118 PolarHBondContact O-N 2.97Å; L118-A120 PolarHBondContact O-N 2.88Å; L118-L121 WeakPolarHBondContact O-CB 3.45Å; L118-L121 PolarHBondContact O-N 3.48Å; L118-V122 WeakPolarHBondContact O-CG2 3.36Å; L118-V122 PolarHBondContact O-N 2.85Å; L118-Y214 HydrophobicContact CD1-CD2 3.47Å; L118-Y214 VanDerWaalsContact CD1-CD2 3.47Å; L118-Y214 HydrophobicContact CD1-CE2 3.86Å; L118-L217 HydrophobicContact CB-CD1 4.05Å
119	L	98.2	Very high	97.8	Very high	3 Å²	3	45.3 Å²	45.3	2%	0.016	25%	0.246	C	C	.	.	H	α-helix	trans	-57.7	-36.6	174.7	-80.9	163.6	0	0	0	112	V115 L116 L121 V122 K123 I179 Y182 F183 L217	V115-L119 HydrophobicContact CG1-CD1 3.94Å; V115-L119 HydrophobicContact CG1-CG 4.41Å; V115-L119 WeakPolarHBondContact O-CB 3.35Å; V115-L119 WeakPolarHBondContact O-CG 3.37Å; V115-L119 PolarHBondContact O-N 3.05Å; L116-L119 HydrophobicContact CD2-CD1 4.37Å; L116-L119 WeakPolarHBondContact O-CB 3.36Å; L116-L119 PolarHBondContact O-N 2.92Å; L119-L121 VanDerWaalsContact C-N 3.26Å; L119-L121 PolarHBondContact O-N 3.15Å; L119-V122 PolarHBondContact O-N 3.24Å; L119-K123 HydrophobicContact CD2-CG 4.48Å; L119-K123 VanDerWaalsContact O-CB 3.24Å; L119-K123 WeakPolarHBondContact O-CB 3.44Å; L119-K123 WeakPolarHBondContact O-CE 3.46Å; L119-K123 VanDerWaalsContact O-CG 3.22Å; L119-K123 WeakPolarHBondContact O-CG 3.36Å; L119-K123 PolarHBondContact O-N 3.13Å; L119-I179 HydrophobicContact CD2-CB 4.38Å; L119-I179 HydrophobicContact CD2-CG1 4.06Å; L119-I179 HydrophobicContact CD2-CG2 3.7Å; L119-Y182 HydrophobicContact CD1-CD1 3.92Å; L119-Y182 HydrophobicContact CD1-CE1 3.95Å; L119-F183 HydrophobicContact CD1-CE1 4.45Å; L119-F183 HydrophobicContact CD1-CE2 4.26Å; L119-F183 HydrophobicContact CD1-CZ 3.77Å; L119-L217 HydrophobicContact CD2-CD1 4.15Å; L119-L217 HydrophobicContact CD2-CD2 3.64Å; L119-L217 HydrophobicContact CD2-CG 4.48Å; L119-L217 HydrophobicContact CG-CD1 3.87Å; L119-L217 HydrophobicContact CG-CD2 4.21Å
120	A	98.1	Very high	98	Very high	59 Å²	59	45.5 Å²	45.5	49%	0.488	25%	0.245	S	C	.	.	H	α-helix	trans	-64.7	-31	176.5	0	0	0	0	0	112.6	L116 S117 L118 P124	L116-A120 PolarHBondContact O-N 2.77Å; S117-A120 WeakPolarHBondContact O-CB 3.42Å; S117-A120 PolarHBondContact O-N 3.26Å; L118-A120 PolarHBondContact O-N 2.88Å; A120-P124 WeakPolarHBondContact O-CD 3.29Å; A120-P124 WeakPolarHBondContact O-CG 3.39Å
121	L	97.5	Very high	98.1	Very high	69 Å²	69	48.3 Å²	48.3	36%	0.361	25%	0.254	S	S	.	.	H	α-helix	trans	-81	-41	175.8	-61.5	172.6	0	0	0	112.5	L46 S117 L118 L119	L46-L121 HydrophobicContact CD1-CD1 4.29Å; S117-L121 PolarHBondContact O-N 3.5Å; L118-L121 WeakPolarHBondContact O-CB 3.45Å; L118-L121 PolarHBondContact O-N 3.48Å; L119-L121 VanDerWaalsContact C-N 3.26Å; L119-L121 PolarHBondContact O-N 3.15Å
122	V	98.4	Very high	98.2	Very high	0 Å²	0	48.3 Å²	48.3	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-81.6	-39	-172.8	178.9	0	0	0	0	112.6	L118 L119 E125 V126 L217 M220 V221	L118-V122 WeakPolarHBondContact O-CG2 3.36Å; L118-V122 PolarHBondContact O-N 2.85Å; L119-V122 PolarHBondContact O-N 3.24Å; V122-E125 PolarHBondContact O-N 2.86Å; V122-E125 VanDerWaalsContact O-N 3.12Å; V122-V126 HydrophobicContact CG1-CG2 4.13Å; V122-V126 PolarHBondContact O-N 2.9Å; V122-V126 VanDerWaalsContact O-N 3.17Å; V122-L217 HydrophobicContact CB-CD2 3.99Å; V122-L217 HydrophobicContact CG1-CD2 3.97Å; V122-L217 HydrophobicContact CG2-CB 4.38Å; V122-L217 HydrophobicContact CG2-CD2 4.21Å; V122-M220 HydrophobicContact CG1-CB 4.18Å; V122-M220 HydrophobicContact CG1-SD 4.35Å; V122-V221 HydrophobicContact CG1-CG2 4.39Å; V122-V221 HydrophobicContact CG2-CG2 3.63Å
123	K	98.4	Very high	98.3	Very high	78 Å²	78	48.2 Å²	48.2	34%	0.339	24%	0.244	S	C	.	.	H	α-helix	trans	-54.1	-49.1	-177.6	-79.4	-179.7	-62.3	-178.4	0	113	L119 E125 V126 W127 I179	L119-K123 HydrophobicContact CD2-CG 4.48Å; L119-K123 VanDerWaalsContact O-CB 3.24Å; L119-K123 WeakPolarHBondContact O-CB 3.44Å; L119-K123 WeakPolarHBondContact O-CE 3.46Å; L119-K123 VanDerWaalsContact O-CG 3.22Å; L119-K123 WeakPolarHBondContact O-CG 3.36Å; L119-K123 PolarHBondContact O-N 3.13Å; K123-E125 VanDerWaalsContact C-N 3.26Å; K123-E125 PolarHBondContact O-N 3.04Å; K123-V126 PolarHBondContact O-N 3.48Å; K123-W127 PolarHBondContact O-N 3.29Å; K123-W127 VanDerWaalsContact O-N 3.11Å; K123-I179 HydrophobicContact CD-CG2 4.12Å; K123-I179 HydrophobicContact CG-CD1 4.1Å; K123-I179 HydrophobicContact CG-CG2 4.04Å
124	P	98.6	Very high	98.3	Very high	64 Å²	64	45.9 Å²	45.9	42%	0.416	24%	0.235	S	C	.	.	H	α-helix	trans	-58	-38.1	179.2	-25	35.3	0	0	0	112.9	A120 W127 T128	A120-P124 WeakPolarHBondContact O-CD 3.29Å; A120-P124 WeakPolarHBondContact O-CG 3.39Å; P124-W127 PolarHBondContact O-N 2.96Å; P124-T128 VanDerWaalsContact O-CB 3.26Å; P124-T128 WeakPolarHBondContact O-CB 3.35Å; P124-T128 PolarHBondContact O-N 3.18Å; P124-T128 PolarHBondContact O-OG1 3.49Å
125	E	98.7	Very high	98.4	Very high	11 Å²	11	41.5 Å²	41.5	5%	0.051	22%	0.217	C	C	.	.	H	α-helix	trans	-68.8	-38.4	-178.8	-59.7	-56.7	142.7	0	0	112.2	K39 Y42 L43 V122 K123 T128 L129 L224	K39-E125 IonicContact NZ-OE1 3.38Å; K39-E125 PolarHBondContact NZ-OE1 3.34Å; K39-E125 IonicContact NZ-OE2 3.78Å; K39-E125 PolarHBondContact NZ-OE2 2.98Å; Y42-E125 HydrophobicContact CE1-CG 4.28Å; Y42-E125 VanDerWaalsContact CE1-OE1 3.26Å; Y42-E125 WeakPolarHBondContact CE1-OE1 3.49Å; L43-E125 HydrophobicContact CD2-CB 4.38Å; L43-E125 HydrophobicContact CD2-CG 4Å; V122-E125 PolarHBondContact O-N 2.86Å; V122-E125 VanDerWaalsContact O-N 3.12Å; K123-E125 VanDerWaalsContact C-N 3.26Å; K123-E125 PolarHBondContact O-N 3.04Å; E125-T128 PolarHBondContact O-N 2.64Å; E125-L129 PolarHBondContact O-N 3.46Å; E125-L224 HydrophobicContact CB-CD1 3.73Å
126	V	98.7	Very high	98.4	Very high	1 Å²	1	41.6 Å²	41.6	1%	0.006	22%	0.217	C	C	.	.	H	α-helix	trans	-62.2	-47.8	173	175.7	0	0	0	0	111	V122 K123 T128 K130 V172 F175 Q176 I179 L224	V122-V126 HydrophobicContact CG1-CG2 4.13Å; V122-V126 PolarHBondContact O-N 2.9Å; V122-V126 VanDerWaalsContact O-N 3.17Å; K123-V126 PolarHBondContact O-N 3.48Å; V126-T128 PolarHBondContact O-N 2.75Å; V126-K130 PolarHBondContact O-N 3.39Å; V126-K130 VanDerWaalsContact O-N 3.14Å; V126-V172 HydrophobicContact CG1-CG1 3.78Å; V126-V172 VanDerWaalsContact O-CG1 3.24Å; V126-V172 WeakPolarHBondContact O-CG1 3.49Å; V126-F175 HydrophobicContact CG1-CB 4.07Å; V126-F175 HydrophobicContact CG2-CB 4.28Å; V126-F175 HydrophobicContact CG2-CD2 4.45Å; V126-Q176 HydrophobicContact CG1-CG 3.58Å; V126-I179 HydrophobicContact CG2-CD1 4.25Å; V126-L224 HydrophobicContact CG2-CD1 4.03Å
127	W	98.6	Very high	98.4	Very high	151 Å²	151	39.6 Å²	39.6	57%	0.572	21%	0.207	S	C	*	.	H	α-helix	trans	-62.1	-44.1	178	-78.1	110.5	0	0	0	112.2	K123 P124 K130 E131 Q176	K123-W127 PolarHBondContact O-N 3.29Å; K123-W127 VanDerWaalsContact O-N 3.11Å; P124-W127 PolarHBondContact O-N 2.96Å; W127-K130 WeakPolarHBondContact O-CB 3.47Å; W127-K130 PolarHBondContact O-N 2.98Å; W127-E131 PolarHBondContact O-N 3.5Å; W127-Q176 VanDerWaalsContact CD2-NE2 3.28Å
128	T	98.7	Very high	98.5	Very high	33 Å²	33	38 Å²	38	20%	0.202	19%	0.194	C	C	.	.	H	α-helix	trans	-61.5	-48.7	-179.3	-60.1	0	0	0	0	111.1	F35 P124 E125 V126 K130 E131 K132	F35-T128 HydrophobicContact CE1-CG2 4.11Å; F35-T128 HydrophobicContact CZ-CG2 3.53Å; P124-T128 VanDerWaalsContact O-CB 3.26Å; P124-T128 WeakPolarHBondContact O-CB 3.35Å; P124-T128 PolarHBondContact O-N 3.18Å; P124-T128 PolarHBondContact O-OG1 3.49Å; E125-T128 PolarHBondContact O-N 2.64Å; V126-T128 PolarHBondContact O-N 2.75Å; T128-K130 VanDerWaalsContact C-N 3.31Å; T128-K130 PolarHBondContact O-N 3.23Å; T128-E131 WeakPolarHBondContact O-CB 3.42Å; T128-E131 PolarHBondContact O-N 3.36Å; T128-K132 WeakPolarHBondContact O-CG 3.28Å; T128-K132 PolarHBondContact O-N 3.06Å
129	L	98.7	Very high	98.5	Very high	0 Å²	0	38.5 Å²	38.5	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-63.6	-38.4	178.9	179.8	59.3	0	0	0	111.4	E125 E131 K132 C133 V168 V172 L224 F227 Y228 L231	E125-L129 PolarHBondContact O-N 3.46Å; L129-E131 VanDerWaalsContact C-N 3.35Å; L129-E131 PolarHBondContact O-N 2.97Å; L129-K132 PolarHBondContact O-N 2.86Å; L129-C133 PolarHBondContact O-N 2.95Å; L129-C133 PolarHBondContact O-SG 3.44Å; L129-V168 HydrophobicContact CD2-CG1 4.39Å; L129-V172 HydrophobicContact CD2-CG2 3.61Å; L129-V172 HydrophobicContact CG-CG2 4.01Å; L129-L224 HydrophobicContact CB-CD2 4.03Å; L129-L224 HydrophobicContact CD2-CD2 3.46Å; L129-L224 VanDerWaalsContact CD2-CD2 3.46Å; L129-L224 HydrophobicContact CG-CD2 4.38Å; L129-F227 HydrophobicContact CD2-CB 3.9Å; L129-F227 HydrophobicContact CD2-CD2 3.97Å; L129-F227 HydrophobicContact CD2-CG 4.45Å; L129-Y228 HydrophobicContact CB-CE2 4.38Å; L129-Y228 HydrophobicContact CD1-CD1 3.88Å; L129-Y228 HydrophobicContact CD1-CE1 3.47Å; L129-Y228 VanDerWaalsContact CD1-CE1 3.47Å; L129-Y228 HydrophobicContact CD1-CE2 4.22Å; L129-Y228 HydrophobicContact CD1-CG 4.44Å; L129-L231 HydrophobicContact CD1-CD1 4.05Å
130	K	98.7	Very high	98.5	Very high	39 Å²	39	38.3 Å²	38.3	17%	0.17	20%	0.195	C	C	.	.	H	α-helix	trans	-58.7	-46	175.3	-174.5	178.4	-176.2	172.9	0	111.8	V126 W127 T128 C133 I134 V172 E173	V126-K130 PolarHBondContact O-N 3.39Å; V126-K130 VanDerWaalsContact O-N 3.14Å; W127-K130 WeakPolarHBondContact O-CB 3.47Å; W127-K130 PolarHBondContact O-N 2.98Å; T128-K130 VanDerWaalsContact C-N 3.31Å; T128-K130 PolarHBondContact O-N 3.23Å; K130-C133 PolarHBondContact O-N 3.48Å; K130-I134 HydrophobicContact CG-CD1 4.46Å; K130-I134 WeakPolarHBondContact O-CG1 3.35Å; K130-I134 PolarHBondContact O-N 3.15Å; K130-I134 VanDerWaalsContact O-N 3.11Å; K130-V172 HydrophobicContact CB-CG1 3.89Å; K130-E173 HydrophobicContact CD-CG 4.21Å; K130-E173 WeakPolarHBondContact CE-OE1 3.41Å; K130-E173 IonicContact NZ-OE1 2.9Å; K130-E173 PolarHBondContact NZ-OE1 3.49Å
131	E	98.6	Very high	98.6	Very high	109 Å²	109	40.6 Å²	40.6	51%	0.509	20%	0.195	S	C	.	.	H	α-helix	trans	-59.9	-46.1	176.2	-171.9	-161.6	118.3	0	0	111.2	W127 T128 L129 C133 I134 L135	W127-E131 PolarHBondContact O-N 3.5Å; T128-E131 WeakPolarHBondContact O-CB 3.42Å; T128-E131 PolarHBondContact O-N 3.36Å; L129-E131 VanDerWaalsContact C-N 3.35Å; L129-E131 PolarHBondContact O-N 2.97Å; E131-C133 PolarHBondContact O-N 3.14Å; E131-I134 WeakPolarHBondContact O-CB 3.48Å; E131-I134 PolarHBondContact O-N 3.46Å; E131-I134 VanDerWaalsContact O-N 3.13Å; E131-L135 PolarHBondContact O-N 3.39Å
132	K	98.6	Very high	98.6	Very high	32 Å²	32	41 Å²	41	14%	0.139	20%	0.195	C	C	.	.	H	α-helix	trans	-68.7	-31.8	179	-60.2	-46.8	176.1	-155.4	0	113.2	F31 F35 T128 L129 I134 L135 V136	F31-K132 HydrophobicContact CD2-CB 3.96Å; F31-K132 HydrophobicContact CD2-CD 4.04Å; F31-K132 HydrophobicContact CD2-CG 3.85Å; F31-K132 HydrophobicContact CE2-CB 3.54Å; F31-K132 HydrophobicContact CE2-CD 4.45Å; F31-K132 HydrophobicContact CE2-CG 3.76Å; F31-K132 HydrophobicContact CZ-CB 4.02Å; F35-K132 HydrophobicContact CD1-CG 4.46Å; F35-K132 HydrophobicContact CE1-CG 3.94Å; F35-K132 HydrophobicContact CZ-CG 4.5Å; T128-K132 WeakPolarHBondContact O-CG 3.28Å; T128-K132 PolarHBondContact O-N 3.06Å; L129-K132 PolarHBondContact O-N 2.86Å; K132-I134 VanDerWaalsContact C-N 3.34Å; K132-L135 HydrophobicContact CD-CD2 4.03Å; K132-L135 WeakPolarHBondContact O-CB 3.28Å; K132-L135 PolarHBondContact O-N 3.04Å; K132-V136 WeakPolarHBondContact O-CG2 3.47Å; K132-V136 PolarHBondContact O-N 3.33Å
133	C	98.8	Very high	98.5	Very high	0 Å²	0	42.1 Å²	42.1	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-61.5	-43	169.2	-72.7	0	0	0	0	111.4	L129 K130 E131 V136 I137 V165 K169	L129-C133 PolarHBondContact O-N 2.95Å; L129-C133 PolarHBondContact O-SG 3.44Å; K130-C133 PolarHBondContact O-N 3.48Å; E131-C133 PolarHBondContact O-N 3.14Å; C133-V136 PolarHBondContact O-N 2.78Å; C133-I137 WeakPolarHBondContact O-CB 3.17Å; C133-I137 WeakPolarHBondContact O-CD1 3.17Å; C133-I137 WeakPolarHBondContact O-CG1 3.33Å; C133-I137 PolarHBondContact O-N 2.98Å; C133-V165 HydrophobicContact CB-CG1 4.27Å; C133-K169 HydrophobicContact CB-CB 3.95Å; C133-K169 HydrophobicContact CB-CG 4.26Å
134	I	98.8	Very high	98.5	Very high	76 Å²	76	41.5 Å²	41.5	39%	0.39	20%	0.2	S	C	.	.	H	α-helix	trans	-62.2	-46.4	176.6	-65.9	164	0	0	0	110.1	K130 E131 K132 V136 I137 T138 K169	K130-I134 HydrophobicContact CG-CD1 4.46Å; K130-I134 WeakPolarHBondContact O-CG1 3.35Å; K130-I134 PolarHBondContact O-N 3.15Å; K130-I134 VanDerWaalsContact O-N 3.11Å; E131-I134 WeakPolarHBondContact O-CB 3.48Å; E131-I134 PolarHBondContact O-N 3.46Å; E131-I134 VanDerWaalsContact O-N 3.13Å; K132-I134 VanDerWaalsContact C-N 3.34Å; I134-V136 PolarHBondContact O-N 3.44Å; I134-I137 PolarHBondContact O-N 3.28Å; I134-T138 PolarHBondContact O-N 3.4Å; I134-T138 PolarHBondContact O-OG1 3.35Å; I134-T138 VanDerWaalsContact O-OG1 3.05Å; I134-K169 HydrophobicContact CG1-CD 4.47Å
135	L	98.7	Very high	98.3	Very high	17 Å²	17	40.3 Å²	40.3	9%	0.089	19%	0.193	C	C	.	.	H	α-helix	trans	-52.7	-52.9	175.6	176.3	71	0	0	0	111.7	L24 E27 F31 E131 K132 I137 T138 W139	L24-L135 HydrophobicContact CD1-CD1 3.59Å; E27-L135 HydrophobicContact CB-CD1 3.96Å; E27-L135 HydrophobicContact CB-CD2 4.24Å; F31-L135 HydrophobicContact CB-CD2 4.1Å; F31-L135 HydrophobicContact CG-CD2 4.48Å; E131-L135 PolarHBondContact O-N 3.39Å; K132-L135 HydrophobicContact CD-CD2 4.03Å; K132-L135 WeakPolarHBondContact O-CB 3.28Å; K132-L135 PolarHBondContact O-N 3.04Å; L135-I137 PolarHBondContact O-N 3.44Å; L135-T138 PolarHBondContact O-N 2.91Å; L135-W139 WeakPolarHBondContact O-CB 3.18Å; L135-W139 PolarHBondContact O-N 3.02Å
136	V	98.6	Very high	98.2	Very high	2 Å²	2	47.4 Å²	47.4	1%	0.012	22%	0.223	C	C	.	.	H	α-helix	trans	-64.8	-41.3	-178.7	173.2	0	0	0	0	111.6	F31 K132 C133 I134 W139 I140 V165 I235	F31-V136 HydrophobicContact CD1-CG2 3.68Å; F31-V136 HydrophobicContact CE1-CG2 3.43Å; F31-V136 VanDerWaalsContact CE1-CG2 3.43Å; F31-V136 HydrophobicContact CZ-CG2 4.33Å; K132-V136 WeakPolarHBondContact O-CG2 3.47Å; K132-V136 PolarHBondContact O-N 3.33Å; C133-V136 PolarHBondContact O-N 2.78Å; I134-V136 PolarHBondContact O-N 3.44Å; V136-W139 HydrophobicContact CG1-CE3 4.37Å; V136-W139 PolarHBondContact O-N 3.5Å; V136-I140 HydrophobicContact CG1-CD1 3.82Å; V136-I140 HydrophobicContact CG1-CG1 4.37Å; V136-I140 WeakPolarHBondContact O-CG1 3.14Å; V136-I140 PolarHBondContact O-N 3.28Å; V136-V165 HydrophobicContact CB-CG1 4.28Å; V136-V165 HydrophobicContact CG1-CG1 4.13Å; V136-V165 HydrophobicContact CG1-CG2 3.91Å; V136-I235 HydrophobicContact CG1-CD1 3.83Å
137	I	98.8	Very high	98	Very high	12 Å²	12	55 Å²	55	6%	0.062	26%	0.262	C	S	.	.	H	α-helix	trans	-59.1	-50.3	176	-72.1	161.1	0	0	0	110	C133 I134 L135 W139 I140 Q141 L162 V165 N166 K169	C133-I137 WeakPolarHBondContact O-CB 3.17Å; C133-I137 WeakPolarHBondContact O-CD1 3.17Å; C133-I137 WeakPolarHBondContact O-CG1 3.33Å; C133-I137 PolarHBondContact O-N 2.98Å; I134-I137 PolarHBondContact O-N 3.28Å; L135-I137 PolarHBondContact O-N 3.44Å; I137-W139 VanDerWaalsContact C-N 3.33Å; I137-W139 PolarHBondContact O-N 2.91Å; I137-I140 PolarHBondContact O-N 3.12Å; I137-Q141 HydrophobicContact CG2-CG 4.47Å; I137-Q141 WeakPolarHBondContact O-CB 3.34Å; I137-Q141 VanDerWaalsContact O-CG 3.24Å; I137-Q141 WeakPolarHBondContact O-CG 3.48Å; I137-Q141 PolarHBondContact O-N 3.14Å; I137-L162 HydrophobicContact CB-CD2 4.2Å; I137-L162 HydrophobicContact CG1-CD2 4.21Å; I137-L162 HydrophobicContact CG2-CD2 3.99Å; I137-V165 HydrophobicContact CD1-CG1 4.08Å; I137-V165 HydrophobicContact CG1-CB 4.14Å; I137-V165 HydrophobicContact CG1-CG1 3.64Å; I137-N166 WeakPolarHBondContact CD1-OD1 3.21Å; I137-K169 HydrophobicContact CD1-CD 3.95Å
138	T	98.7	Very high	97.7	Very high	36 Å²	36	53 Å²	53	22%	0.221	26%	0.259	C	S	.	.	H	α-helix	trans	-64.1	-39.8	-179.8	-56.9	0	0	0	0	111.3	F20 L24 I134 L135 Q141 H142	F20-T138 HydrophobicContact CZ-CG2 4.43Å; L24-T138 HydrophobicContact CD1-CG2 4.23Å; L24-T138 HydrophobicContact CD2-CG2 3.88Å; I134-T138 PolarHBondContact O-N 3.4Å; I134-T138 PolarHBondContact O-OG1 3.35Å; I134-T138 VanDerWaalsContact O-OG1 3.05Å; L135-T138 PolarHBondContact O-N 2.91Å; T138-Q141 PolarHBondContact O-N 3.35Å; T138-H142 PolarHBondContact O-N 2.99Å; T138-H142 VanDerWaalsContact O-N 3.16Å; T138-H142 PolarHBondContact O-ND1 3.44Å
139	W	98.7	Very high	97.4	Very high	16 Å²	16	59.8 Å²	59.8	6%	0.061	30%	0.295	C	S	.	.	H	α-helix	trans	-60.5	-52.1	175.7	169.9	61.1	0	0	0	112.2	L24 F25 A28 L32 L135 V136 I137 Q141 H142 L143 I235 L239 I242 V243	L24-W139 HydrophobicContact CD1-CB 4.35Å; L24-W139 HydrophobicContact CG-CB 4.43Å; F25-W139 AromaticContact CD2-CD1 3.93Å; A28-W139 HydrophobicContact CB-CB 3.94Å; A28-W139 HydrophobicContact CB-CD2 3.73Å; A28-W139 HydrophobicContact CB-CE3 4.32Å; A28-W139 HydrophobicContact CB-CG 3.53Å; L32-W139 HydrophobicContact CD1-CH2 3.89Å; L32-W139 HydrophobicContact CD1-CZ3 4.07Å; L135-W139 WeakPolarHBondContact O-CB 3.18Å; L135-W139 PolarHBondContact O-N 3.02Å; V136-W139 HydrophobicContact CG1-CE3 4.37Å; V136-W139 PolarHBondContact O-N 3.5Å; I137-W139 VanDerWaalsContact C-N 3.33Å; I137-W139 PolarHBondContact O-N 2.91Å; W139-Q141 VanDerWaalsContact C-N 3.3Å; W139-Q141 PolarHBondContact O-N 3.43Å; W139-H142 PolarHBondContact O-N 3.02Å; W139-H142 VanDerWaalsContact O-N 3.1Å; W139-L143 HydrophobicContact CD2-CD1 4.12Å; W139-L143 HydrophobicContact CH2-CD1 4.35Å; W139-L143 HydrophobicContact CZ2-CD1 3.65Å; W139-L143 PolarHBondContact O-N 3.17Å; W139-I235 HydrophobicContact CH2-CG2 4.33Å; W139-I235 HydrophobicContact CZ3-CG2 4.15Å; W139-L239 HydrophobicContact CH2-CD1 4.11Å; W139-I242 HydrophobicContact CH2-CG2 3.97Å; W139-I242 HydrophobicContact CZ3-CG2 4.24Å; W139-V243 HydrophobicContact CZ2-CG2 4.24Å
140	I	98.3	Very high	97	Very high	0 Å²	0	61.3 Å²	61.3	0%	0	31%	0.31	C	S	.	.	H	α-helix	trans	-63.5	-38.4	179.4	-61.3	170.5	0	0	0	110.7	V136 I137 H142 L143 I144 Q158 V161 L162 I242	V136-I140 HydrophobicContact CG1-CD1 3.82Å; V136-I140 HydrophobicContact CG1-CG1 4.37Å; V136-I140 WeakPolarHBondContact O-CG1 3.14Å; V136-I140 PolarHBondContact O-N 3.28Å; I137-I140 PolarHBondContact O-N 3.12Å; I140-H142 VanDerWaalsContact C-N 3.25Å; I140-H142 PolarHBondContact O-N 3.31Å; I140-L143 WeakPolarHBondContact O-CA 3.48Å; I140-L143 WeakPolarHBondContact O-CB 3.14Å; I140-L143 PolarHBondContact O-N 3.45Å; I140-I144 PolarHBondContact O-N 3.11Å; I140-Q158 HydrophobicContact CG2-CB 4.11Å; I140-Q158 HydrophobicContact CG2-CG 4.42Å; I140-V161 HydrophobicContact CD1-CB 4.49Å; I140-V161 HydrophobicContact CD1-CG1 3.68Å; I140-L162 HydrophobicContact CB-CD1 4.46Å; I140-L162 HydrophobicContact CB-CD2 4.01Å; I140-L162 HydrophobicContact CB-CG 4.07Å; I140-L162 HydrophobicContact CG2-CD1 3.86Å; I140-L162 HydrophobicContact CG2-CD2 4.21Å; I140-L162 HydrophobicContact CG2-CG 3.7Å; I140-I242 HydrophobicContact CG1-CG2 4.17Å
141	Q	98.3	Very high	96.7	Very high	106 Å²	106	64.2 Å²	64.2	50%	0.495	33%	0.328	S	S	.	.	H	α-helix	trans	-59	-34.6	175.3	-76.9	174.5	-18.1	0	0	113.2	I137 T138 W139 L143 I144 L162	I137-Q141 HydrophobicContact CG2-CG 4.47Å; I137-Q141 WeakPolarHBondContact O-CB 3.34Å; I137-Q141 VanDerWaalsContact O-CG 3.24Å; I137-Q141 WeakPolarHBondContact O-CG 3.48Å; I137-Q141 PolarHBondContact O-N 3.14Å; T138-Q141 PolarHBondContact O-N 3.35Å; W139-Q141 VanDerWaalsContact C-N 3.3Å; W139-Q141 PolarHBondContact O-N 3.43Å; Q141-L143 VanDerWaalsContact C-N 3.29Å; Q141-I144 PolarHBondContact O-N 2.96Å; Q141-L162 HydrophobicContact CG-CD1 4.27Å; Q141-L162 HydrophobicContact CG-CD2 4.43Å
142	H	97.7	Very high	96.6	Very high	79 Å²	79	62.3 Å²	62.3	37%	0.366	32%	0.321	S	S	.	.	H	α-helix	trans	-75.8	-17.2	175.3	-75.5	75.9	0	0	0	113.4	F20 L24 F25 T138 W139 I140	F20-H142 AromaticContact CE1-NE2 3.91Å; L24-H142 HydrophobicContact CD2-CB 4.48Å; F25-H142 HydrophobicContact CE2-CB 3.91Å; F25-H142 HydrophobicContact CZ-CB 4.29Å; T138-H142 PolarHBondContact O-N 2.99Å; T138-H142 VanDerWaalsContact O-N 3.16Å; T138-H142 PolarHBondContact O-ND1 3.44Å; W139-H142 PolarHBondContact O-N 3.02Å; W139-H142 VanDerWaalsContact O-N 3.1Å; I140-H142 VanDerWaalsContact C-N 3.25Å; I140-H142 PolarHBondContact O-N 3.31Å
143	L	97.4	Very high	96.5	Very high	23 Å²	23	68 Å²	68	12%	0.12	35%	0.346	C	S	.	.	H	α-helix	trans	-87.7	-12	174.7	-68.5	173	0	0	0	113	F25 W139 I140 Q141 P145 Q158 I242 V243	F25-L143 HydrophobicContact CE1-CD2 3.6Å; F25-L143 HydrophobicContact CE1-CG 4.37Å; F25-L143 HydrophobicContact CZ-CD2 3.68Å; F25-L143 HydrophobicContact CZ-CG 4.11Å; W139-L143 HydrophobicContact CD2-CD1 4.12Å; W139-L143 HydrophobicContact CH2-CD1 4.35Å; W139-L143 HydrophobicContact CZ2-CD1 3.65Å; W139-L143 PolarHBondContact O-N 3.17Å; I140-L143 WeakPolarHBondContact O-CA 3.48Å; I140-L143 WeakPolarHBondContact O-CB 3.14Å; I140-L143 PolarHBondContact O-N 3.45Å; Q141-L143 VanDerWaalsContact C-N 3.29Å; L143-P145 WeakPolarHBondContact O-CD 3.12Å; L143-Q158 VanDerWaalsContact C-NE2 3.31Å; L143-Q158 PolarHBondContact O-NE2 2.93Å; L143-I242 HydrophobicContact CD1-CG2 3.83Å; L143-V243 HydrophobicContact CD1-CG2 4.33Å
144	I	97.1	Very high	96.4	Very high	64 Å²	64	68 Å²	68	33%	0.328	35%	0.346	S	S	.	.			trans	-67.1	119.8	175.1	-64.1	173.7	0	0	0	108	I140 Q141 V155 L162	I140-I144 PolarHBondContact O-N 3.11Å; Q141-I144 PolarHBondContact O-N 2.96Å; I144-V155 HydrophobicContact CG2-CG1 4.46Å; I144-L162 HydrophobicContact CD1-CD1 3.9Å
145	P	96.2	Very high	96.4	Very high	40 Å²	40	65.3 Å²	65.3	26%	0.26	33%	0.334	S	S	.	.			trans	-74.3	177.2	-176.7	33.3	-36.8	0	0	0	110.8	L143 I147 V155 P245 K246	L143-P145 WeakPolarHBondContact O-CD 3.12Å; P145-I147 PolarHBondContact O-N 3.37Å; P145-V155 HydrophobicContact CG-CG2 3.85Å; P145-P245 HydrophobicContact CG-CG 3.91Å; P145-K246 HydrophobicContact CB-CG 4.42Å; P145-K246 HydrophobicContact CG-CG 4.08Å
146	K	95.8	Very high	96.3	Very high	159 Å²	159	66.8 Å²	66.8	69%	0.691	35%	0.348	S	S	*	.			trans	-55.9	139.1	169.2	-173.5	-174.7	171.2	-160.3	0	109.9	E148	K146-E148 PolarHBondContact O-N 3.34Å
147	I	95.1	Very high	96.3	Very high	160 Å²	160	67.9 Å²	67.9	82%	0.821	35%	0.354	S	S	*	.			trans	-67.9	123.4	174.5	-57.5	173.2	0	0	0	108.6	P145	P145-I147 PolarHBondContact O-N 3.37Å
148	E	92.2	Very high	96.3	Very high	109 Å²	109	67.3 Å²	67.3	51%	0.509	35%	0.351	S	S	.	.			trans	-137.7	160.2	-179.5	-65.2	-174.8	160.7	0	0	108.8	K146 G150	K146-E148 PolarHBondContact O-N 3.34Å; E148-G150 PolarHBondContact O-N 2.95Å
149	D	91.7	Very high	96.3	Very high	177 Å²	177	71.2 Å²	71.2	95%	0.947	37%	0.367	S	S	*	.	S	Bend	trans	-83.1	114.3	179	-170	15.2	0	0	0	109.9
150	G	90.9	Very high	96.3	Very high	32 Å²	32	76.3 Å²	76.3	33%	0.33	39%	0.389	S	S	.	.	S	Bend	trans	91.2	168.9	177.9	0	0	0	0	0	114.7	E148 D152 K246	E148-G150 PolarHBondContact O-N 2.95Å; G150-D152 VanDerWaalsContact C-N 3.31Å; G150-D152 WeakPolarHBondContact CA-OD2 3.22Å; G150-D152 PolarHBondContact N-OD2 3.38Å; G150-D152 VanDerWaalsContact N-OD2 3.15Å; G150-D152 PolarHBondContact O-N 2.85Å; G150-K246 PolarHBondContact O-NZ 3.26Å
151	N	92.1	Very high	96.3	Very high	100 Å²	100	76.5 Å²	76.5	54%	0.535	39%	0.39	S	S	.	.			trans	57.7	39.3	-172.7	-167.1	21.6	0	0	0	112.9	K246	N151-K246 VanDerWaalsContact C-NZ 3.34Å; N151-K246 HydrophobicContact CB-CD 4.13Å; N151-K246 PolarHBondContact ND2-O 3.05Å; N151-K246 VanDerWaalsContact O-CD 3.31Å; N151-K246 WeakPolarHBondContact O-CD 3.36Å; N151-K246 WeakPolarHBondContact O-CE 3.24Å; N151-K246 PolarHBondContact O-NZ 3.48Å
152	D	95.3	Very high	96.3	Very high	69 Å²	69	72.2 Å²	72.2	37%	0.369	37%	0.371	S	S	.	.			trans	-95.1	1.2	-171.9	-58.2	-52.3	0	0	0	114.5	G150 G154 V155 A156 K246	G150-D152 VanDerWaalsContact C-N 3.31Å; G150-D152 WeakPolarHBondContact CA-OD2 3.22Å; G150-D152 PolarHBondContact N-OD2 3.38Å; G150-D152 VanDerWaalsContact N-OD2 3.15Å; G150-D152 PolarHBondContact O-N 2.85Å; D152-G154 VanDerWaalsContact C-N 3.32Å; D152-G154 PolarHBondContact O-N 3.41Å; D152-V155 PolarHBondContact O-N 3.28Å; D152-V155 VanDerWaalsContact O-N 3.1Å; D152-A156 PolarHBondContact O-N 3.49Å; D152-K246 IonicContact OD1-NZ 3.41Å; D152-K246 PolarHBondContact OD1-NZ 3.28Å
153	F	97.1	Very high	96.4	Very high	150 Å²	150	73.9 Å²	73.9	66%	0.658	38%	0.378	S	S	*	.	H	α-helix	trans	-60.4	-40.9	-179.5	-178.1	-104.5	0	0	0	112.6	V155 A156 I157	F153-V155 VanDerWaalsContact C-N 3.33Å; F153-V155 PolarHBondContact O-N 2.9Å; F153-A156 PolarHBondContact O-N 3.37Å; F153-I157 HydrophobicContact CD1-CD1 3.9Å; F153-I157 HydrophobicContact CE1-CD1 3.42Å; F153-I157 VanDerWaalsContact CE1-CD1 3.42Å; F153-I157 HydrophobicContact CE1-CG1 4.3Å; F153-I157 HydrophobicContact CZ-CD1 3.87Å; F153-I157 HydrophobicContact CZ-CG1 4.39Å; F153-I157 WeakPolarHBondContact O-CG1 3.24Å; F153-I157 PolarHBondContact O-N 2.94Å; F153-I157 VanDerWaalsContact O-N 3.08Å
154	G	97.2	Very high	96.4	Very high	1 Å²	1	76.6 Å²	76.6	1%	0.01	39%	0.387	C	S	.	.	H	α-helix	trans	-64.6	-37.5	175.1	0	0	0	0	0	112.7	D152 I157 Q158	D152-G154 VanDerWaalsContact C-N 3.32Å; D152-G154 PolarHBondContact O-N 3.41Å; G154-I157 WeakPolarHBondContact O-CB 3.45Å; G154-I157 PolarHBondContact O-N 2.84Å; G154-Q158 PolarHBondContact O-N 3.07Å
155	V	97.8	Very high	96.5	Very high	20 Å²	20	73.6 Å²	73.6	12%	0.121	37%	0.372	C	S	.	.	H	α-helix	trans	-67	-41.9	176.1	-176.3	0	0	0	0	110.6	I144 P145 D152 F153 I157 Q158 E159 P245	I144-V155 HydrophobicContact CG2-CG1 4.46Å; P145-V155 HydrophobicContact CG-CG2 3.85Å; D152-V155 PolarHBondContact O-N 3.28Å; D152-V155 VanDerWaalsContact O-N 3.1Å; F153-V155 VanDerWaalsContact C-N 3.33Å; F153-V155 PolarHBondContact O-N 2.9Å; V155-I157 VanDerWaalsContact C-N 3.26Å; V155-I157 PolarHBondContact O-N 3.18Å; V155-Q158 WeakPolarHBondContact O-CA 3.44Å; V155-Q158 WeakPolarHBondContact O-CB 3.35Å; V155-Q158 PolarHBondContact O-N 2.99Å; V155-E159 WeakPolarHBondContact O-CG 3.3Å; V155-E159 PolarHBondContact O-N 3.38Å; V155-P245 HydrophobicContact CG2-CB 4.33Å
156	A	98.2	Very high	96.6	Very high	48 Å²	48	74.6 Å²	74.6	40%	0.397	38%	0.375	S	S	.	.	H	α-helix	trans	-60.9	-34.2	174.2	0	0	0	0	0	112.5	D152 F153 K160	D152-A156 PolarHBondContact O-N 3.49Å; F153-A156 PolarHBondContact O-N 3.37Å; A156-K160 WeakPolarHBondContact O-CB 3.47Å; A156-K160 PolarHBondContact O-N 3.05Å
157	I	98.4	Very high	96.8	Very high	25 Å²	25	68.9 Å²	68.9	13%	0.128	36%	0.358	C	S	.	.	H	α-helix	trans	-65.6	-46.1	171.4	-69.8	169.3	0	0	0	110.7	F153 G154 V155 E159 K160 V161 N238 K241	F153-I157 HydrophobicContact CD1-CD1 3.9Å; F153-I157 HydrophobicContact CE1-CD1 3.42Å; F153-I157 VanDerWaalsContact CE1-CD1 3.42Å; F153-I157 HydrophobicContact CE1-CG1 4.3Å; F153-I157 HydrophobicContact CZ-CD1 3.87Å; F153-I157 HydrophobicContact CZ-CG1 4.39Å; F153-I157 WeakPolarHBondContact O-CG1 3.24Å; F153-I157 PolarHBondContact O-N 2.94Å; F153-I157 VanDerWaalsContact O-N 3.08Å; G154-I157 WeakPolarHBondContact O-CB 3.45Å; G154-I157 PolarHBondContact O-N 2.84Å; V155-I157 VanDerWaalsContact C-N 3.26Å; V155-I157 PolarHBondContact O-N 3.18Å; I157-E159 VanDerWaalsContact C-N 3.3Å; I157-E159 PolarHBondContact O-N 2.92Å; I157-K160 PolarHBondContact O-N 3.31Å; I157-V161 HydrophobicContact CG2-CG2 4.31Å; I157-V161 VanDerWaalsContact O-CG2 3.3Å; I157-V161 WeakPolarHBondContact O-CG2 3.42Å; I157-V161 PolarHBondContact O-N 3.08Å; I157-N238 HydrophobicContact CG2-CB 3.88Å; I157-K241 HydrophobicContact CB-CB 4.36Å; I157-K241 HydrophobicContact CD1-CB 3.83Å; I157-K241 HydrophobicContact CD1-CG 3.79Å; I157-K241 HydrophobicContact CG2-CB 4.09Å
158	Q	98.4	Very high	96.9	Very high	0 Å²	0	61.3 Å²	61.3	0%	0	32%	0.319	C	S	.	.	H	α-helix	trans	-56.3	-45.1	175.9	-70.1	175.1	-42.4	0	0	111.4	I140 L143 G154 V155 V161 L162 I242	I140-Q158 HydrophobicContact CG2-CB 4.11Å; I140-Q158 HydrophobicContact CG2-CG 4.42Å; L143-Q158 VanDerWaalsContact C-NE2 3.31Å; L143-Q158 PolarHBondContact O-NE2 2.93Å; G154-Q158 PolarHBondContact O-N 3.07Å; V155-Q158 WeakPolarHBondContact O-CA 3.44Å; V155-Q158 WeakPolarHBondContact O-CB 3.35Å; V155-Q158 PolarHBondContact O-N 2.99Å; Q158-V161 PolarHBondContact O-N 3.37Å; Q158-L162 WeakPolarHBondContact O-CB 3.47Å; Q158-L162 PolarHBondContact O-N 3.46Å; Q158-I242 PolarHBondContact NE2-O 3.25Å
159	E	98.3	Very high	97.3	Very high	118 Å²	118	58.5 Å²	58.5	55%	0.551	31%	0.305	S	S	*	.	H	α-helix	trans	-61.1	-43.6	176.4	-70.3	177.6	171.7	0	0	112.1	V155 I157 V161 L162 E163	V155-E159 WeakPolarHBondContact O-CG 3.3Å; V155-E159 PolarHBondContact O-N 3.38Å; I157-E159 VanDerWaalsContact C-N 3.3Å; I157-E159 PolarHBondContact O-N 2.92Å; E159-V161 PolarHBondContact O-N 2.87Å; E159-L162 WeakPolarHBondContact O-CB 3.42Å; E159-L162 PolarHBondContact O-N 3.44Å; E159-E163 PolarHBondContact O-N 2.95Å
160	K	98.5	Very high	97.6	Very high	123 Å²	123	54.3 Å²	54.3	54%	0.535	29%	0.285	S	S	.	.	H	α-helix	trans	-66.4	-38	179	-165.4	71.9	-166.9	163.5	0	112.5	A156 I157 E163 R164	A156-K160 WeakPolarHBondContact O-CB 3.47Å; A156-K160 PolarHBondContact O-N 3.05Å; I157-K160 PolarHBondContact O-N 3.31Å; K160-E163 WeakPolarHBondContact CD-OE2 3.46Å; K160-E163 WeakPolarHBondContact CE-OE2 3.46Å; K160-E163 IonicContact NZ-OE1 3.33Å; K160-E163 PolarHBondContact NZ-OE1 3.4Å; K160-E163 IonicContact NZ-OE2 3.18Å; K160-E163 PolarHBondContact NZ-OE2 3.23Å; K160-E163 PolarHBondContact O-N 3.15Å; K160-R164 PolarHBondContact O-N 2.77Å
161	V	98.6	Very high	98	Very high	3 Å²	3	57.6 Å²	57.6	2%	0.018	29%	0.291	C	S	.	.	H	α-helix	trans	-66.3	-45.6	174	177.5	0	0	0	0	109.7	I140 I157 Q158 E159 E163 R164 V165 I234 I235 N238 I242	I140-V161 HydrophobicContact CD1-CB 4.49Å; I140-V161 HydrophobicContact CD1-CG1 3.68Å; I157-V161 HydrophobicContact CG2-CG2 4.31Å; I157-V161 VanDerWaalsContact O-CG2 3.3Å; I157-V161 WeakPolarHBondContact O-CG2 3.42Å; I157-V161 PolarHBondContact O-N 3.08Å; Q158-V161 PolarHBondContact O-N 3.37Å; E159-V161 PolarHBondContact O-N 2.87Å; V161-E163 VanDerWaalsContact C-N 3.32Å; V161-E163 PolarHBondContact O-N 3.13Å; V161-R164 PolarHBondContact O-N 3.35Å; V161-R164 VanDerWaalsContact O-N 3.07Å; V161-V165 HydrophobicContact CG1-CG2 4.32Å; V161-V165 WeakPolarHBondContact O-CG2 3.2Å; V161-V165 PolarHBondContact O-N 3.44Å; V161-I234 HydrophobicContact CG2-CD1 4.39Å; V161-I234 HydrophobicContact CG2-CG1 4.27Å; V161-I235 HydrophobicContact CG1-CG1 4.22Å; V161-N238 HydrophobicContact CG2-CB 4.39Å; V161-I242 HydrophobicContact CB-CD1 4.49Å; V161-I242 HydrophobicContact CG1-CD1 4.1Å; V161-I242 HydrophobicContact CG2-CD1 4.03Å; V161-I242 HydrophobicContact CG2-CG1 4.28Å
162	L	98.7	Very high	98.3	Very high	17 Å²	17	52.9 Å²	52.9	9%	0.089	27%	0.265	C	S	.	.	H	α-helix	trans	-57.8	-41.8	175.1	-86.5	170.8	0	0	0	112.6	I137 I140 Q141 I144 Q158 E159 R164 V165 N166	I137-L162 HydrophobicContact CB-CD2 4.2Å; I137-L162 HydrophobicContact CG1-CD2 4.21Å; I137-L162 HydrophobicContact CG2-CD2 3.99Å; I140-L162 HydrophobicContact CB-CD1 4.46Å; I140-L162 HydrophobicContact CB-CD2 4.01Å; I140-L162 HydrophobicContact CB-CG 4.07Å; I140-L162 HydrophobicContact CG2-CD1 3.86Å; I140-L162 HydrophobicContact CG2-CD2 4.21Å; I140-L162 HydrophobicContact CG2-CG 3.7Å; Q141-L162 HydrophobicContact CG-CD1 4.27Å; Q141-L162 HydrophobicContact CG-CD2 4.43Å; I144-L162 HydrophobicContact CD1-CD1 3.9Å; Q158-L162 WeakPolarHBondContact O-CB 3.47Å; Q158-L162 PolarHBondContact O-N 3.46Å; E159-L162 WeakPolarHBondContact O-CB 3.42Å; E159-L162 PolarHBondContact O-N 3.44Å; L162-R164 VanDerWaalsContact C-N 3.28Å; L162-R164 PolarHBondContact O-N 2.96Å; L162-V165 PolarHBondContact O-N 2.74Å; L162-N166 WeakPolarHBondContact O-CB 3.49Å; L162-N166 PolarHBondContact O-N 3.21Å; L162-N166 PolarHBondContact O-ND2 3.36Å
163	E	98.8	Very high	98.4	Very high	113 Å²	113	52.6 Å²	52.6	53%	0.528	26%	0.262	S	S	.	.	H	α-helix	trans	-56.5	-45.7	174.5	-173.2	-166.7	153.5	0	0	110.4	E159 K160 V161 N166 A167	E159-E163 PolarHBondContact O-N 2.95Å; K160-E163 WeakPolarHBondContact CD-OE2 3.46Å; K160-E163 WeakPolarHBondContact CE-OE2 3.46Å; K160-E163 IonicContact NZ-OE1 3.33Å; K160-E163 PolarHBondContact NZ-OE1 3.4Å; K160-E163 IonicContact NZ-OE2 3.18Å; K160-E163 PolarHBondContact NZ-OE2 3.23Å; K160-E163 PolarHBondContact O-N 3.15Å; V161-E163 VanDerWaalsContact C-N 3.32Å; V161-E163 PolarHBondContact O-N 3.13Å; E163-N166 PolarHBondContact O-N 3.08Å; E163-A167 WeakPolarHBondContact O-CB 3.36Å; E163-A167 PolarHBondContact O-N 3.19Å
164	R	98.6	Very high	98.5	Very high	81 Å²	81	47.8 Å²	47.8	31%	0.306	25%	0.25	S	C	.	.	H	α-helix	trans	-66.1	-44.8	178.7	-177.7	56.7	-176.8	-170.9	0.7	112.5	K160 V161 L162 N166 A167 V168 E230 I234	K160-R164 PolarHBondContact O-N 2.77Å; V161-R164 PolarHBondContact O-N 3.35Å; V161-R164 VanDerWaalsContact O-N 3.07Å; L162-R164 VanDerWaalsContact C-N 3.28Å; L162-R164 PolarHBondContact O-N 2.96Å; R164-N166 VanDerWaalsContact C-N 3.3Å; R164-N166 PolarHBondContact O-N 3.3Å; R164-A167 WeakPolarHBondContact O-CB 3.48Å; R164-A167 PolarHBondContact O-N 3.3Å; R164-V168 PolarHBondContact O-N 3.4Å; R164-E230 IonicContact CZ-OE2 3.33Å; R164-E230 IonicContact NE-OE2 3.76Å; R164-E230 VanDerWaalsContact NH2-CD 3.26Å; R164-E230 IonicContact NH2-OE1 3.39Å; R164-E230 PolarHBondContact NH2-OE1 3.08Å; R164-E230 IonicContact NH2-OE2 2.77Å; R164-E230 PolarHBondContact NH2-OE2 2.78Å; R164-I234 HydrophobicContact CB-CD1 3.81Å; R164-I234 HydrophobicContact CG-CD1 3.94Å
165	V	98.7	Very high	98.5	Very high	0 Å²	0	48.9 Å²	48.9	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-62.5	-40.7	179.1	-175.3	0	0	0	0	110.4	C133 V136 I137 V161 L162 V168 K169 L231	C133-V165 HydrophobicContact CB-CG1 4.27Å; V136-V165 HydrophobicContact CB-CG1 4.28Å; V136-V165 HydrophobicContact CG1-CG1 4.13Å; V136-V165 HydrophobicContact CG1-CG2 3.91Å; I137-V165 HydrophobicContact CD1-CG1 4.08Å; I137-V165 HydrophobicContact CG1-CB 4.14Å; I137-V165 HydrophobicContact CG1-CG1 3.64Å; V161-V165 HydrophobicContact CG1-CG2 4.32Å; V161-V165 WeakPolarHBondContact O-CG2 3.2Å; V161-V165 PolarHBondContact O-N 3.44Å; L162-V165 PolarHBondContact O-N 2.74Å; V165-V168 PolarHBondContact O-N 3.16Å; V165-K169 PolarHBondContact O-N 3.12Å; V165-L231 HydrophobicContact CB-CD2 4.28Å; V165-L231 HydrophobicContact CG1-CD2 4.27Å; V165-L231 HydrophobicContact CG2-CD2 3.78Å
166	N	98.8	Very high	98.5	Very high	61 Å²	61	49.2 Å²	49.2	33%	0.326	26%	0.255	S	S	.	.	H	α-helix	trans	-64.4	-41.2	174	-80.5	-71.1	0	0	0	112.2	I137 L162 E163 R164 V168 K169 T170	I137-N166 WeakPolarHBondContact CD1-OD1 3.21Å; L162-N166 WeakPolarHBondContact O-CB 3.49Å; L162-N166 PolarHBondContact O-N 3.21Å; L162-N166 PolarHBondContact O-ND2 3.36Å; E163-N166 PolarHBondContact O-N 3.08Å; R164-N166 VanDerWaalsContact C-N 3.3Å; R164-N166 PolarHBondContact O-N 3.3Å; N166-V168 VanDerWaalsContact C-N 3.32Å; N166-V168 PolarHBondContact O-N 3.35Å; N166-K169 WeakPolarHBondContact O-CB 3.29Å; N166-K169 PolarHBondContact O-N 3.36Å; N166-T170 PolarHBondContact O-N 3.12Å; N166-T170 PolarHBondContact O-OG1 3.38Å; N166-T170 VanDerWaalsContact O-OG1 3.09Å
167	A	98.8	Very high	98.4	Very high	40 Å²	40	50.3 Å²	50.3	33%	0.331	26%	0.257	S	S	.	.	H	α-helix	trans	-60.9	-40.7	176.2	0	0	0	0	0	112.2	E163 R164 K171	E163-A167 WeakPolarHBondContact O-CB 3.36Å; E163-A167 PolarHBondContact O-N 3.19Å; R164-A167 WeakPolarHBondContact O-CB 3.48Å; R164-A167 PolarHBondContact O-N 3.3Å; A167-K171 PolarHBondContact O-N 2.8Å
168	V	98.8	Very high	98.4	Very high	1 Å²	1	51 Å²	51	1%	0.006	26%	0.262	C	S	.	.	H	α-helix	trans	-62.2	-49	172.6	170.7	0	0	0	0	110.4	L129 R164 V165 N166 T170 K171 V172 F227 L231	L129-V168 HydrophobicContact CD2-CG1 4.39Å; R164-V168 PolarHBondContact O-N 3.4Å; V165-V168 PolarHBondContact O-N 3.16Å; N166-V168 VanDerWaalsContact C-N 3.32Å; N166-V168 PolarHBondContact O-N 3.35Å; V168-T170 VanDerWaalsContact C-N 3.31Å; V168-T170 PolarHBondContact O-N 3.41Å; V168-K171 WeakPolarHBondContact O-CB 3.33Å; V168-K171 PolarHBondContact O-N 3.27Å; V168-K171 VanDerWaalsContact O-N 3.08Å; V168-V172 HydrophobicContact CG1-CG2 4.36Å; V168-V172 WeakPolarHBondContact O-CG2 3.49Å; V168-V172 PolarHBondContact O-N 3.43Å; V168-F227 HydrophobicContact CG1-CB 3.75Å; V168-F227 HydrophobicContact CG1-CD1 4.3Å; V168-F227 HydrophobicContact CG1-CD2 3.92Å; V168-F227 HydrophobicContact CG1-CG 3.73Å; V168-F227 HydrophobicContact CG2-CD1 4.11Å; V168-F227 HydrophobicContact CG2-CG 4.34Å; V168-L231 HydrophobicContact CG1-CD1 4.27Å; V168-L231 HydrophobicContact CG2-CD2 4.34Å
169	K	98.8	Very high	98.3	Very high	50 Å²	50	51.8 Å²	51.8	22%	0.217	27%	0.266	C	S	.	.	H	α-helix	trans	-54.3	-45.9	177.8	-177	-171.5	164.6	-165.5	0	112.1	C133 I134 I137 V165 N166 K171 V172 E173	C133-K169 HydrophobicContact CB-CB 3.95Å; C133-K169 HydrophobicContact CB-CG 4.26Å; I134-K169 HydrophobicContact CG1-CD 4.47Å; I137-K169 HydrophobicContact CD1-CD 3.95Å; V165-K169 PolarHBondContact O-N 3.12Å; N166-K169 WeakPolarHBondContact O-CB 3.29Å; N166-K169 PolarHBondContact O-N 3.36Å; K169-K171 VanDerWaalsContact C-N 3.31Å; K169-K171 PolarHBondContact O-N 2.9Å; K169-V172 PolarHBondContact O-N 3.21Å; K169-V172 VanDerWaalsContact O-N 3.14Å; K169-E173 WeakPolarHBondContact CE-OE1 3.38Å; K169-E173 IonicContact NZ-OE1 3.93Å; K169-E173 WeakPolarHBondContact O-CG 3.32Å; K169-E173 PolarHBondContact O-N 3.23Å
170	T	98.8	Very high	98.2	Very high	88 Å²	88	49.8 Å²	49.8	54%	0.54	27%	0.265	S	S	.	.	H	α-helix	trans	-59.7	-40.3	178	-58.8	0	0	0	0	112.1	N166 V168 E173 A174	N166-T170 PolarHBondContact O-N 3.12Å; N166-T170 PolarHBondContact O-OG1 3.38Å; N166-T170 VanDerWaalsContact O-OG1 3.09Å; V168-T170 VanDerWaalsContact C-N 3.31Å; V168-T170 PolarHBondContact O-N 3.41Å; T170-E173 PolarHBondContact O-N 2.77Å; T170-A174 PolarHBondContact O-N 2.63Å
171	K	98.6	Very high	98.2	Very high	102 Å²	102	49 Å²	49	44%	0.443	26%	0.262	S	S	.	.	H	α-helix	trans	-65.5	-40.5	175.3	-68.7	-175.8	179.8	-172	0	112	A167 V168 K169 E173 A174 F175 F227	A167-K171 PolarHBondContact O-N 2.8Å; V168-K171 WeakPolarHBondContact O-CB 3.33Å; V168-K171 PolarHBondContact O-N 3.27Å; V168-K171 VanDerWaalsContact O-N 3.08Å; K169-K171 VanDerWaalsContact C-N 3.31Å; K169-K171 PolarHBondContact O-N 2.9Å; K171-E173 VanDerWaalsContact C-N 3.32Å; K171-E173 PolarHBondContact O-N 3.18Å; K171-A174 WeakPolarHBondContact O-CB 3.39Å; K171-A174 PolarHBondContact O-N 2.96Å; K171-A174 VanDerWaalsContact O-N 3.15Å; K171-F175 PolarHBondContact O-N 2.82Å; K171-F175 VanDerWaalsContact O-N 3.11Å; K171-F227 HydrophobicContact CB-CE2 4.08Å; K171-F227 HydrophobicContact CB-CZ 3.95Å; K171-F227 HydrophobicContact CD-CE1 3.89Å; K171-F227 HydrophobicContact CD-CE2 4.4Å; K171-F227 HydrophobicContact CD-CZ 3.47Å; K171-F227 VanDerWaalsContact CD-CZ 3.47Å; K171-F227 HydrophobicContact CG-CZ 4.39Å
172	V	98.6	Very high	98.2	Very high	0 Å²	0	49.8 Å²	49.8	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-64.8	-36.9	176.1	178.6	0	0	0	0	111.4	V126 L129 K130 V168 K169 A174 F175 Q176 L224 F227	V126-V172 HydrophobicContact CG1-CG1 3.78Å; V126-V172 VanDerWaalsContact O-CG1 3.24Å; V126-V172 WeakPolarHBondContact O-CG1 3.49Å; L129-V172 HydrophobicContact CD2-CG2 3.61Å; L129-V172 HydrophobicContact CG-CG2 4.01Å; K130-V172 HydrophobicContact CB-CG1 3.89Å; V168-V172 HydrophobicContact CG1-CG2 4.36Å; V168-V172 WeakPolarHBondContact O-CG2 3.49Å; V168-V172 PolarHBondContact O-N 3.43Å; K169-V172 PolarHBondContact O-N 3.21Å; K169-V172 VanDerWaalsContact O-N 3.14Å; V172-A174 VanDerWaalsContact C-N 3.33Å; V172-F175 WeakPolarHBondContact O-CB 3.49Å; V172-F175 PolarHBondContact O-N 2.9Å; V172-Q176 PolarHBondContact O-N 2.85Å; V172-L224 HydrophobicContact CG2-CD2 4.48Å; V172-F227 HydrophobicContact CG2-CD2 4.21Å; V172-F227 HydrophobicContact CG2-CE2 4.4Å
173	E	98.2	Very high	98.2	Very high	63 Å²	63	53.6 Å²	53.6	29%	0.294	28%	0.281	S	S	.	.	H	α-helix	trans	-65.5	-34.9	172.6	-71.7	177.5	160.8	0	0	112.5	K130 K169 T170 K171 F175 Q176 T177	K130-E173 HydrophobicContact CD-CG 4.21Å; K130-E173 WeakPolarHBondContact CE-OE1 3.41Å; K130-E173 IonicContact NZ-OE1 2.9Å; K130-E173 PolarHBondContact NZ-OE1 3.49Å; K169-E173 WeakPolarHBondContact CE-OE1 3.38Å; K169-E173 IonicContact NZ-OE1 3.93Å; K169-E173 WeakPolarHBondContact O-CG 3.32Å; K169-E173 PolarHBondContact O-N 3.23Å; T170-E173 PolarHBondContact O-N 2.77Å; K171-E173 VanDerWaalsContact C-N 3.32Å; K171-E173 PolarHBondContact O-N 3.18Å; E173-F175 VanDerWaalsContact C-N 3.33Å; E173-F175 PolarHBondContact O-N 3.34Å; E173-Q176 WeakPolarHBondContact O-CB 3.15Å; E173-Q176 PolarHBondContact O-N 3.38Å; E173-T177 PolarHBondContact O-N 3.28Å; E173-T177 PolarHBondContact O-OG1 3.27Å
174	A	98.6	Very high	98.1	Very high	49 Å²	49	51.2 Å²	51.2	41%	0.405	28%	0.277	S	S	.	.	H	α-helix	trans	-62.7	-40	171.9	0	0	0	0	0	111.5	T170 K171 V172 Q176 T177 T178	T170-A174 PolarHBondContact O-N 2.63Å; K171-A174 WeakPolarHBondContact O-CB 3.39Å; K171-A174 PolarHBondContact O-N 2.96Å; K171-A174 VanDerWaalsContact O-N 3.15Å; V172-A174 VanDerWaalsContact C-N 3.33Å; A174-Q176 VanDerWaalsContact C-N 3.32Å; A174-Q176 PolarHBondContact O-N 3.3Å; A174-T177 WeakPolarHBondContact O-CB 3.5Å; A174-T177 PolarHBondContact O-N 2.93Å; A174-T177 VanDerWaalsContact O-N 3.08Å; A174-T178 PolarHBondContact O-N 3.37Å; A174-T178 PolarHBondContact O-OG1 3.47Å
175	F	98.6	Very high	98.1	Very high	24 Å²	24	50.6 Å²	50.6	11%	0.105	28%	0.277	C	S	.	.	H	α-helix	trans	-59.1	-41.3	174.9	-60	-22.1	0	0	0	112.7	V126 K171 V172 E173 T177 T178 I179 M220 D223 L224 F227	V126-F175 HydrophobicContact CG1-CB 4.07Å; V126-F175 HydrophobicContact CG2-CB 4.28Å; V126-F175 HydrophobicContact CG2-CD2 4.45Å; K171-F175 PolarHBondContact O-N 2.82Å; K171-F175 VanDerWaalsContact O-N 3.11Å; V172-F175 WeakPolarHBondContact O-CB 3.49Å; V172-F175 PolarHBondContact O-N 2.9Å; E173-F175 VanDerWaalsContact C-N 3.33Å; E173-F175 PolarHBondContact O-N 3.34Å; F175-T177 VanDerWaalsContact C-N 3.26Å; F175-T177 PolarHBondContact O-N 3.17Å; F175-T178 PolarHBondContact O-N 2.88Å; F175-I179 WeakPolarHBondContact O-CG1 3.12Å; F175-I179 PolarHBondContact O-N 3.47Å; F175-M220 HydrophobicContact CB-CE 4.13Å; F175-M220 HydrophobicContact CB-CG 4.2Å; F175-M220 HydrophobicContact CB-SD 3.86Å; F175-M220 HydrophobicContact CD1-CE 4.23Å; F175-M220 HydrophobicContact CD1-CG 3.74Å; F175-M220 HydrophobicContact CD1-SD 4.37Å; F175-M220 HydrophobicContact CD2-CB 4.39Å; F175-M220 HydrophobicContact CD2-CG 4.06Å; F175-M220 HydrophobicContact CE1-CG 4.04Å; F175-M220 HydrophobicContact CE2-CB 4.45Å; F175-M220 HydrophobicContact CE2-CG 4.33Å; F175-M220 HydrophobicContact CG-CE 4.42Å; F175-M220 HydrophobicContact CG-CG 3.76Å; F175-M220 HydrophobicContact CG-SD 4.1Å; F175-M220 HydrophobicContact CZ-CG 4.33Å; F175-D223 HydrophobicContact CE2-CB 4.1Å; F175-D223 HydrophobicContact CZ-CB 3.68Å; F175-L224 HydrophobicContact CD2-CD2 4.47Å; F175-L224 HydrophobicContact CE2-CD2 4.4Å; F175-F227 AromaticContact CE2-CE2 3.83Å; F175-F227 HydrophobicContact CE2-CE2 3.83Å; F175-F227 AromaticContact CZ-CE2 3.96Å; F175-F227 HydrophobicContact CZ-CE2 3.96Å; F175-F227 HydrophobicContact CZ-CZ 4.44Å
176	Q	96.6	Very high	98.1	Very high	28 Å²	28	51.9 Å²	51.9	13%	0.131	28%	0.282	C	S	.	.	H	α-helix	trans	-60.2	-39	175.5	-61.8	-175.6	-39.1	0	0	111.8	V126 W127 V172 E173 A174 S180	V126-Q176 HydrophobicContact CG1-CG 3.58Å; W127-Q176 VanDerWaalsContact CD2-NE2 3.28Å; V172-Q176 PolarHBondContact O-N 2.85Å; E173-Q176 WeakPolarHBondContact O-CB 3.15Å; E173-Q176 PolarHBondContact O-N 3.38Å; A174-Q176 VanDerWaalsContact C-N 3.32Å; A174-Q176 PolarHBondContact O-N 3.3Å; Q176-S180 WeakPolarHBondContact O-CB 3.43Å; Q176-S180 PolarHBondContact O-N 3.36Å; Q176-S180 VanDerWaalsContact O-N 3.09Å; Q176-S180 PolarHBondContact O-OG 3.15Å
177	T	96.9	Very high	98.1	Very high	71 Å²	71	50.8 Å²	50.8	44%	0.436	29%	0.285	S	S	.	.	H	α-helix	trans	-66.8	-45.9	177.1	-55.4	0	0	0	0	111	E173 A174 F175 S180 K181	E173-T177 PolarHBondContact O-N 3.28Å; E173-T177 PolarHBondContact O-OG1 3.27Å; A174-T177 WeakPolarHBondContact O-CB 3.5Å; A174-T177 PolarHBondContact O-N 2.93Å; A174-T177 VanDerWaalsContact O-N 3.08Å; F175-T177 VanDerWaalsContact C-N 3.26Å; F175-T177 PolarHBondContact O-N 3.17Å; T177-S180 PolarHBondContact O-N 2.91Å; T177-K181 HydrophobicContact CG2-CD 4.27Å; T177-K181 HydrophobicContact CG2-CG 4.49Å; T177-K181 WeakPolarHBondContact O-CG 3.41Å; T177-K181 PolarHBondContact O-N 3.14Å
178	T	97.5	Very high	98	Very high	40 Å²	40	53.5 Å²	53.5	25%	0.245	29%	0.294	C	S	.	.	H	α-helix	trans	-58.8	-47.7	176.5	-60.6	0	0	0	0	111.8	A174 F175 S180 K181 Y182 E216 M220	A174-T178 PolarHBondContact O-N 3.37Å; A174-T178 PolarHBondContact O-OG1 3.47Å; F175-T178 PolarHBondContact O-N 2.88Å; T178-S180 VanDerWaalsContact C-N 3.29Å; T178-S180 PolarHBondContact O-N 3.23Å; T178-K181 PolarHBondContact O-N 3.11Å; T178-Y182 PolarHBondContact O-N 3.5Å; T178-Y182 VanDerWaalsContact O-N 3.12Å; T178-E216 HydrophobicContact CG2-CB 4.49Å; T178-E216 HydrophobicContact CG2-CG 4.47Å; T178-E216 WeakPolarHBondContact CG2-OE2 3.25Å; T178-M220 HydrophobicContact CG2-CE 3.58Å
179	I	97.4	Very high	98	Very high	15 Å²	15	53.6 Å²	53.6	8%	0.077	30%	0.295	C	S	.	.	H	α-helix	trans	-57.6	-43.2	176.2	-72.1	166.2	0	0	0	111.5	L119 K123 V126 F175 F183 L217 M220	L119-I179 HydrophobicContact CD2-CB 4.38Å; L119-I179 HydrophobicContact CD2-CG1 4.06Å; L119-I179 HydrophobicContact CD2-CG2 3.7Å; K123-I179 HydrophobicContact CD-CG2 4.12Å; K123-I179 HydrophobicContact CG-CD1 4.1Å; K123-I179 HydrophobicContact CG-CG2 4.04Å; V126-I179 HydrophobicContact CG2-CD1 4.25Å; F175-I179 WeakPolarHBondContact O-CG1 3.12Å; F175-I179 PolarHBondContact O-N 3.47Å; I179-F183 HydrophobicContact CG2-CE2 4.34Å; I179-F183 VanDerWaalsContact O-CD2 3.27Å; I179-F183 WeakPolarHBondContact O-CD2 3.35Å; I179-L217 HydrophobicContact CG1-CD2 4.41Å; I179-M220 HydrophobicContact CD1-SD 4.08Å; I179-M220 HydrophobicContact CG1-CE 4.23Å; I179-M220 HydrophobicContact CG1-SD 4.11Å
180	S	95.9	Very high	98	Very high	77 Å²	77	52.3 Å²	52.3	54%	0.538	29%	0.291	S	S	.	.	H	α-helix	trans	-67.3	-40.6	179.9	-56.2	0	0	0	0	111.6	Q176 T177 T178 Y182 F183	Q176-S180 WeakPolarHBondContact O-CB 3.43Å; Q176-S180 PolarHBondContact O-N 3.36Å; Q176-S180 VanDerWaalsContact O-N 3.09Å; Q176-S180 PolarHBondContact O-OG 3.15Å; T177-S180 PolarHBondContact O-N 2.91Å; T178-S180 VanDerWaalsContact C-N 3.29Å; T178-S180 PolarHBondContact O-N 3.23Å; S180-Y182 VanDerWaalsContact C-N 3.34Å; S180-Y182 PolarHBondContact O-N 3.38Å; S180-F183 PolarHBondContact O-N 3.32Å
181	K	97.9	Very high	97.9	Very high	107 Å²	107	50.5 Å²	50.5	47%	0.465	29%	0.285	S	S	.	.	H	α-helix	trans	-64.2	-34.5	179.8	-78.9	-179.4	176.6	-177.6	0	113.2	T177 T178 F183 S184 E185	T177-K181 HydrophobicContact CG2-CD 4.27Å; T177-K181 HydrophobicContact CG2-CG 4.49Å; T177-K181 WeakPolarHBondContact O-CG 3.41Å; T177-K181 PolarHBondContact O-N 3.14Å; T178-K181 PolarHBondContact O-N 3.11Å; K181-F183 VanDerWaalsContact C-N 3.27Å; K181-F183 PolarHBondContact O-N 2.91Å; K181-S184 WeakPolarHBondContact CA-OG 3.27Å; K181-S184 PolarHBondContact O-N 3.19Å; K181-S184 PolarHBondContact O-OG 3.02Å; K181-E185 WeakPolarHBondContact O-CB 3.45Å; K181-E185 WeakPolarHBondContact O-CG 3.28Å; K181-E185 PolarHBondContact O-N 3Å
182	Y	98.4	Very high	97.8	Very high	19 Å²	19	50.5 Å²	50.5	8%	0.075	29%	0.285	C	S	.	.	H	α-helix	trans	-51.8	-47	176.9	167.6	-108.7	0	0	0	111.8	V115 L119 T178 S180 E185 R186 D210 A213	V115-Y182 HydrophobicContact CG1-CD1 4.49Å; V115-Y182 HydrophobicContact CG1-CE1 3.72Å; V115-Y182 HydrophobicContact CG1-CE2 4.21Å; L119-Y182 HydrophobicContact CD1-CD1 3.92Å; L119-Y182 HydrophobicContact CD1-CE1 3.95Å; T178-Y182 PolarHBondContact O-N 3.5Å; T178-Y182 VanDerWaalsContact O-N 3.12Å; S180-Y182 VanDerWaalsContact C-N 3.34Å; S180-Y182 PolarHBondContact O-N 3.38Å; Y182-E185 PolarHBondContact O-N 3.19Å; Y182-R186 HydrophobicContact CE2-CB 4.27Å; Y182-R186 WeakPolarHBondContact O-CB 3.35Å; Y182-R186 PolarHBondContact O-N 3.08Å; Y182-R186 VanDerWaalsContact OH-CD 3.22Å; Y182-R186 WeakPolarHBondContact OH-CD 3.39Å; Y182-R186 PolarHBondContact OH-NE 3.2Å; Y182-D210 PolarHBondContact OH-OD1 3.26Å; Y182-A213 HydrophobicContact CD2-CB 3.4Å; Y182-A213 VanDerWaalsContact CD2-CB 3.4Å; Y182-A213 HydrophobicContact CE2-CB 3.54Å; Y182-A213 HydrophobicContact CG-CB 4.11Å
183	F	98.2	Very high	97.7	Very high	97 Å²	97	50.6 Å²	50.6	43%	0.425	29%	0.285	S	S	.	.	H	α-helix	trans	-63.7	-44.9	-178.6	-66.7	-78	0	0	0	112.6	L116 L119 I179 S180 K181 G187	L116-F183 HydrophobicContact CD2-CE1 3.73Å; L116-F183 HydrophobicContact CD2-CZ 4.22Å; L119-F183 HydrophobicContact CD1-CE1 4.45Å; L119-F183 HydrophobicContact CD1-CE2 4.26Å; L119-F183 HydrophobicContact CD1-CZ 3.77Å; I179-F183 HydrophobicContact CG2-CE2 4.34Å; I179-F183 VanDerWaalsContact O-CD2 3.27Å; I179-F183 WeakPolarHBondContact O-CD2 3.35Å; S180-F183 PolarHBondContact O-N 3.32Å; K181-F183 VanDerWaalsContact C-N 3.27Å; K181-F183 PolarHBondContact O-N 2.91Å; F183-G187 PolarHBondContact O-N 2.82Å
184	S	97.9	Very high	97.5	Very high	63 Å²	63	49.4 Å²	49.4	44%	0.441	28%	0.284	S	S	.	.	H	α-helix	trans	-67.9	-46.3	178.2	49.1	0	0	0	0	111.9	K181 G187 D188	K181-S184 WeakPolarHBondContact CA-OG 3.27Å; K181-S184 PolarHBondContact O-N 3.19Å; K181-S184 PolarHBondContact O-OG 3.02Å; S184-G187 PolarHBondContact O-N 3.24Å; S184-D188 PolarHBondContact O-N 3.42Å
185	E	98.4	Very high	97.2	Very high	68 Å²	68	54.4 Å²	54.4	32%	0.318	30%	0.297	S	S	.	.	H	α-helix	trans	-69.6	-39.2	-175.6	-69.3	-178.2	-171.4	0	0	111.9	K181 Y182 A189 R209	K181-E185 WeakPolarHBondContact O-CB 3.45Å; K181-E185 WeakPolarHBondContact O-CG 3.28Å; K181-E185 PolarHBondContact O-N 3Å; Y182-E185 PolarHBondContact O-N 3.19Å; E185-A189 WeakPolarHBondContact O-CB 3.44Å; E185-A189 PolarHBondContact O-N 3.08Å; E185-R209 IonicContact OE2-CZ 3.5Å; E185-R209 IonicContact OE2-NE 3.25Å; E185-R209 IonicContact OE2-NH1 2.97Å; E185-R209 PolarHBondContact OE2-NH1 2.91Å; E185-R209 IonicContact OE2-NH2 3.09Å
186	R	98.6	Very high	96.9	Very high	26 Å²	26	56.5 Å²	56.5	10%	0.098	31%	0.307	C	S	.	.	H	α-helix	trans	-66.4	-42.8	172.1	-172.1	-178.4	-169.2	-82.6	-0.3	111.1	P110 Y182 D188 A189 V190 D210	P110-R186 PolarHBondContact O-NH1 2.82Å; Y182-R186 HydrophobicContact CE2-CB 4.27Å; Y182-R186 WeakPolarHBondContact O-CB 3.35Å; Y182-R186 PolarHBondContact O-N 3.08Å; Y182-R186 VanDerWaalsContact OH-CD 3.22Å; Y182-R186 WeakPolarHBondContact OH-CD 3.39Å; Y182-R186 PolarHBondContact OH-NE 3.2Å; R186-D188 VanDerWaalsContact C-N 3.34Å; R186-D188 PolarHBondContact O-N 3.09Å; R186-A189 PolarHBondContact O-N 3.22Å; R186-V190 HydrophobicContact CG-CG2 4.38Å; R186-V190 VanDerWaalsContact O-CG2 3.32Å; R186-V190 WeakPolarHBondContact O-CG2 3.49Å; R186-V190 PolarHBondContact O-N 3.04Å; R186-D210 VanDerWaalsContact CD-OD1 3.29Å; R186-D210 WeakPolarHBondContact CD-OD1 3.33Å; R186-D210 IonicContact CZ-OD1 2.74Å; R186-D210 IonicContact CZ-OD2 3.91Å; R186-D210 IonicContact NE-OD1 3.44Å; R186-D210 PolarHBondContact NE-OD1 2.72Å; R186-D210 IonicContact NE-OD2 3.99Å; R186-D210 PolarHBondContact NE-OD2 3.16Å; R186-D210 IonicContact NH2-OD1 2.77Å; R186-D210 IonicContact NH2-OD2 2.68Å; R186-D210 PolarHBondContact NH2-OD2 3.15Å
187	G	98.1	Very high	96.7	Very high	38 Å²	38	55.5 Å²	55.5	39%	0.392	30%	0.303	S	S	.	.	H	α-helix	trans	-56.7	-47.2	176.2	0	0	0	0	0	112.1	F183 S184 V190 A191	F183-G187 PolarHBondContact O-N 2.82Å; S184-G187 PolarHBondContact O-N 3.24Å; G187-V190 PolarHBondContact O-N 3.23Å; G187-A191 WeakPolarHBondContact O-CB 3.44Å; G187-A191 PolarHBondContact O-N 3.2Å
188	D	98.3	Very high	96.4	Very high	98 Å²	98	58 Å²	58	52%	0.524	31%	0.309	S	S	.	.	H	α-helix	trans	-64.8	-39.8	176.8	-73.6	-15.6	0	0	0	112.4	S184 R186 A191 K192	S184-D188 PolarHBondContact O-N 3.42Å; R186-D188 VanDerWaalsContact C-N 3.34Å; R186-D188 PolarHBondContact O-N 3.09Å; D188-A191 PolarHBondContact O-N 2.83Å; D188-K192 WeakPolarHBondContact O-CB 3.4Å; D188-K192 VanDerWaalsContact O-CG 3.31Å; D188-K192 WeakPolarHBondContact O-CG 3.48Å; D188-K192 PolarHBondContact O-N 3.09Å
189	A	98.3	Very high	96.3	Very high	2 Å²	2	58 Å²	58	2%	0.017	31%	0.309	C	S	.	.	H	α-helix	trans	-63.9	-45	176.4	0	0	0	0	0	111.6	E185 R186 K192 A193 L205 V206	E185-A189 WeakPolarHBondContact O-CB 3.44Å; E185-A189 PolarHBondContact O-N 3.08Å; R186-A189 PolarHBondContact O-N 3.22Å; A189-K192 PolarHBondContact O-N 3.21Å; A189-A193 WeakPolarHBondContact O-CB 3.43Å; A189-A193 PolarHBondContact O-N 3.28Å; A189-L205 HydrophobicContact CB-CD2 3.9Å; A189-L205 HydrophobicContact CB-CG 3.95Å; A189-V206 HydrophobicContact CB-CG2 3.77Å
190	V	97.9	Very high	96.2	Very high	23 Å²	23	61.9 Å²	61.9	14%	0.139	33%	0.328	C	S	.	.	H	α-helix	trans	-63.3	-44.4	175.8	171.8	0	0	0	0	110.8	L109 R186 G187 K192 A193 S194 V206	L109-V190 HydrophobicContact CB-CG1 4.21Å; L109-V190 HydrophobicContact CD1-CG1 3.49Å; L109-V190 VanDerWaalsContact CD1-CG1 3.49Å; R186-V190 HydrophobicContact CG-CG2 4.38Å; R186-V190 VanDerWaalsContact O-CG2 3.32Å; R186-V190 WeakPolarHBondContact O-CG2 3.49Å; R186-V190 PolarHBondContact O-N 3.04Å; G187-V190 PolarHBondContact O-N 3.23Å; V190-K192 VanDerWaalsContact C-N 3.35Å; V190-K192 PolarHBondContact O-N 2.68Å; V190-A193 PolarHBondContact O-N 3.06Å; V190-S194 WeakPolarHBondContact O-CB 3.27Å; V190-S194 PolarHBondContact O-N 2.93Å; V190-S194 PolarHBondContact O-OG 3.49Å; V190-V206 HydrophobicContact CB-CG2 4.41Å; V190-V206 HydrophobicContact CG2-CB 4.5Å; V190-V206 HydrophobicContact CG2-CG1 3.9Å; V190-V206 HydrophobicContact CG2-CG2 3.67Å
191	A	96.6	Very high	96.4	Very high	50 Å²	50	64.1 Å²	64.1	41%	0.413	33%	0.334	S	S	.	.	H	α-helix	trans	-59	-46.1	177.4	0	0	0	0	0	111.4	G187 D188 S194 K195	G187-A191 WeakPolarHBondContact O-CB 3.44Å; G187-A191 PolarHBondContact O-N 3.2Å; D188-A191 PolarHBondContact O-N 2.83Å; A191-S194 PolarHBondContact O-N 2.96Å; A191-S194 PolarHBondContact O-OG 3.23Å; A191-K195 WeakPolarHBondContact O-CB 3.47Å; A191-K195 PolarHBondContact O-N 3.43Å
192	K	96.6	Very high	96.4	Very high	103 Å²	103	62.4 Å²	62.4	45%	0.448	33%	0.325	S	S	.	.	H	α-helix	trans	-62.7	-45.4	175.6	-73.9	172.8	-177.7	172.9	0	112.2	D188 A189 V190 S194 K195 E196 Y202	D188-K192 WeakPolarHBondContact O-CB 3.4Å; D188-K192 VanDerWaalsContact O-CG 3.31Å; D188-K192 WeakPolarHBondContact O-CG 3.48Å; D188-K192 PolarHBondContact O-N 3.09Å; A189-K192 PolarHBondContact O-N 3.21Å; V190-K192 VanDerWaalsContact C-N 3.35Å; V190-K192 PolarHBondContact O-N 2.68Å; K192-S194 VanDerWaalsContact C-N 3.28Å; K192-S194 PolarHBondContact O-N 2.95Å; K192-K195 PolarHBondContact O-N 3.49Å; K192-E196 PolarHBondContact O-N 3.43Å; K192-Y202 HydrophobicContact CB-CD1 4Å; K192-Y202 HydrophobicContact CB-CD2 3.92Å; K192-Y202 HydrophobicContact CB-CE1 4.18Å; K192-Y202 HydrophobicContact CB-CE2 4.08Å; K192-Y202 HydrophobicContact CB-CG 3.89Å; K192-Y202 HydrophobicContact CD-CD1 4.31Å; K192-Y202 HydrophobicContact CD-CE1 3.9Å
193	A	96	Very high	96.3	Very high	1 Å²	1	62.8 Å²	62.8	1%	0.008	33%	0.326	C	S	.	.	H	α-helix	trans	-60.5	-37.9	177.6	0	0	0	0	0	112.4	I66 A189 V190 R203	I66-A193 HydrophobicContact CD1-CB 3.53Å; A189-A193 WeakPolarHBondContact O-CB 3.43Å; A189-A193 PolarHBondContact O-N 3.28Å; V190-A193 PolarHBondContact O-N 3.06Å; A193-R203 HydrophobicContact CB-CG 4.45Å
194	S	94.2	Very high	96.3	Very high	38 Å²	38	60.8 Å²	60.8	27%	0.266	33%	0.328	S	S	.	.	H	α-helix	trans	-75.8	-27.7	179.9	72.6	0	0	0	0	113.5	V190 A191 K192 T197	V190-S194 WeakPolarHBondContact O-CB 3.27Å; V190-S194 PolarHBondContact O-N 2.93Å; V190-S194 PolarHBondContact O-OG 3.49Å; A191-S194 PolarHBondContact O-N 2.96Å; A191-S194 PolarHBondContact O-OG 3.23Å; K192-S194 VanDerWaalsContact C-N 3.28Å; K192-S194 PolarHBondContact O-N 2.95Å; S194-T197 WeakPolarHBondContact O-CG2 3.5Å
195	K	92.6	Very high	96.4	Very high	155 Å²	155	60.4 Å²	60.4	67%	0.674	32%	0.32	S	S	*	.	H	α-helix	trans	-84.3	-48	179.1	-175.5	-176.4	172.6	-172.3	0	111.7	A191 K192 T197	A191-K195 WeakPolarHBondContact O-CB 3.47Å; A191-K195 PolarHBondContact O-N 3.43Å; K192-K195 PolarHBondContact O-N 3.49Å; K195-T197 PolarHBondContact O-N 3.44Å
196	E	93.1	Very high	96.4	Very high	68 Å²	68	57.1 Å²	57.1	32%	0.318	31%	0.305	S	S	.	.	S	Bend	trans	-103.7	65.2	-177.1	-54.4	-58.5	157.2	0	0	109.6	K192 H198 V199 Y202	K192-E196 PolarHBondContact O-N 3.43Å; E196-H198 PolarHBondContact O-N 3.38Å; E196-H198 VanDerWaalsContact O-N 3.07Å; E196-H198 IonicContact OE2-CE1 3.74Å; E196-H198 PolarHBondContact OE2-CE1 3.23Å; E196-H198 VanDerWaalsContact OE2-CE1 3.25Å; E196-V199 HydrophobicContact CB-CB 4.3Å; E196-V199 HydrophobicContact CB-CG2 3.97Å; E196-V199 PolarHBondContact O-N 2.86Å; E196-Y202 HydrophobicContact CB-CD2 4.05Å; E196-Y202 HydrophobicContact CB-CE2 3.92Å; E196-Y202 HydrophobicContact CG-CE2 4.16Å
197	T	91.8	Very high	96.3	Very high	6 Å²	6	57.5 Å²	57.5	4%	0.037	31%	0.308	C	S	.	.	T	Hydrogen-bonded Turn	trans	-62.1	-19.9	-169.6	50.6	0	0	0	0	114.9	I66 P69 V103 S194 K195	I66-T197 HydrophobicContact CG2-CG2 3.73Å; P69-T197 WeakPolarHBondContact CD-O 3.18Å; P69-T197 WeakPolarHBondContact CG-OG1 3.4Å; V103-T197 HydrophobicContact CG1-CG2 3.94Å; S194-T197 WeakPolarHBondContact O-CG2 3.5Å; K195-T197 PolarHBondContact O-N 3.44Å
198	H	91.4	Very high	96.4	Very high	125 Å²	125	61 Å²	61	58%	0.579	31%	0.314	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82	-15.8	176.3	62.1	-82	0	0	0	113.2	P69 E196 M200	P69-H198 HydrophobicContact CG-CB 4.32Å; E196-H198 PolarHBondContact O-N 3.38Å; E196-H198 VanDerWaalsContact O-N 3.07Å; E196-H198 IonicContact OE2-CE1 3.74Å; E196-H198 PolarHBondContact OE2-CE1 3.23Å; E196-H198 VanDerWaalsContact OE2-CE1 3.25Å; H198-M200 PolarHBondContact O-N 3.37Å
199	V	95.4	Very high	96.4	Very high	39 Å²	39	60.9 Å²	60.9	24%	0.236	31%	0.306	C	S	.	.			trans	-91.3	95.3	179.8	-176.3	0	0	0	0	109.5	E196 D201 Y202	E196-V199 HydrophobicContact CB-CB 4.3Å; E196-V199 HydrophobicContact CB-CG2 3.97Å; E196-V199 PolarHBondContact O-N 2.86Å; V199-D201 HydrophobicContact CG1-CB 4.3Å; V199-D201 PolarHBondContact O-N 3.43Å; V199-Y202 HydrophobicContact CB-CD2 3.71Å; V199-Y202 HydrophobicContact CB-CE2 3.95Å; V199-Y202 HydrophobicContact CG1-CD2 3.67Å; V199-Y202 HydrophobicContact CG1-CE2 3.77Å; V199-Y202 HydrophobicContact CG1-CG 4.23Å; V199-Y202 HydrophobicContact CG2-CE2 4.32Å; V199-Y202 PolarHBondContact O-N 3.37Å
200	M	95.6	Very high	96.4	Very high	96 Å²	96	60.9 Å²	60.9	47%	0.473	31%	0.306	S	S	.	.	H	α-helix	trans	-67.8	-22.9	-175.5	-61.1	-55.7	-72.5	0	0	113.6	I68 H198 Y202 R203 A204	I68-M200 HydrophobicContact CD1-CE 4.35Å; H198-M200 PolarHBondContact O-N 3.37Å; M200-Y202 PolarHBondContact O-N 3.08Å; M200-R203 VanDerWaalsContact CE-CD 3.47Å; M200-R203 WeakPolarHBondContact O-CB 3.49Å; M200-R203 PolarHBondContact O-N 2.89Å; M200-A204 PolarHBondContact O-N 2.65Å
201	D	98.4	Very high	96.4	Very high	124 Å²	124	61 Å²	61	66%	0.663	31%	0.305	S	S	*	.	H	α-helix	trans	-61	-29.8	175.7	-65.5	-59	0	0	0	112.9	V199 R203 A204 L205	V199-D201 HydrophobicContact CG1-CB 4.3Å; V199-D201 PolarHBondContact O-N 3.43Å; D201-R203 VanDerWaalsContact C-N 3.31Å; D201-R203 PolarHBondContact O-N 2.84Å; D201-A204 PolarHBondContact O-N 3.12Å; D201-L205 VanDerWaalsContact O-CB 3.31Å; D201-L205 WeakPolarHBondContact O-CB 3.36Å; D201-L205 PolarHBondContact O-N 3.19Å
202	Y	98.1	Very high	96.5	Very high	72 Å²	72	60.7 Å²	60.7	28%	0.282	30%	0.302	S	S	.	.	H	α-helix	trans	-70.1	-29	175.6	-67	-42.8	0	0	0	112.6	K192 E196 V199 M200 L205 V206	K192-Y202 HydrophobicContact CB-CD1 4Å; K192-Y202 HydrophobicContact CB-CD2 3.92Å; K192-Y202 HydrophobicContact CB-CE1 4.18Å; K192-Y202 HydrophobicContact CB-CE2 4.08Å; K192-Y202 HydrophobicContact CB-CG 3.89Å; K192-Y202 HydrophobicContact CD-CD1 4.31Å; K192-Y202 HydrophobicContact CD-CE1 3.9Å; E196-Y202 HydrophobicContact CB-CD2 4.05Å; E196-Y202 HydrophobicContact CB-CE2 3.92Å; E196-Y202 HydrophobicContact CG-CE2 4.16Å; V199-Y202 HydrophobicContact CB-CD2 3.71Å; V199-Y202 HydrophobicContact CB-CE2 3.95Å; V199-Y202 HydrophobicContact CG1-CD2 3.67Å; V199-Y202 HydrophobicContact CG1-CE2 3.77Å; V199-Y202 HydrophobicContact CG1-CG 4.23Å; V199-Y202 HydrophobicContact CG2-CE2 4.32Å; V199-Y202 PolarHBondContact O-N 3.37Å; M200-Y202 PolarHBondContact O-N 3.08Å; Y202-L205 HydrophobicContact CD1-CD2 4.3Å; Y202-V206 WeakPolarHBondContact O-CG2 3.47Å; Y202-V206 PolarHBondContact O-N 3.22Å; Y202-V206 VanDerWaalsContact O-N 3.17Å
203	R	97.6	Very high	96.5	Very high	26 Å²	26	56 Å²	56	10%	0.098	28%	0.283	C	S	.	.	H	α-helix	trans	-70.5	-44.3	172.5	-59.8	173.9	-177.4	-107.4	1.4	110.5	L64 I66 P67 A193 M200 D201 L205 V206 H207	L64-R203 HydrophobicContact CD2-CB 3.92Å; L64-R203 HydrophobicContact CD2-CG 3.97Å; I66-R203 VanDerWaalsContact O-CZ 3.25Å; I66-R203 PolarHBondContact O-NH1 3.36Å; I66-R203 PolarHBondContact O-NH2 2.77Å; P67-R203 PolarHBondContact O-NH2 3.45Å; P67-R203 VanDerWaalsContact O-NH2 3.08Å; A193-R203 HydrophobicContact CB-CG 4.45Å; M200-R203 VanDerWaalsContact CE-CD 3.47Å; M200-R203 WeakPolarHBondContact O-CB 3.49Å; M200-R203 PolarHBondContact O-N 2.89Å; D201-R203 VanDerWaalsContact C-N 3.31Å; D201-R203 PolarHBondContact O-N 2.84Å; R203-L205 VanDerWaalsContact C-N 3.3Å; R203-L205 PolarHBondContact O-N 3.33Å; R203-V206 PolarHBondContact O-N 3.33Å; R203-H207 PolarHBondContact O-CD2 3.27Å; R203-H207 PolarHBondContact O-N 2.99Å
204	A	97.9	Very high	96.7	Very high	56 Å²	56	56.4 Å²	56.4	46%	0.463	28%	0.284	S	S	.	.	H	α-helix	trans	-59.1	-42.7	173.4	0	0	0	0	0	111.3	M200 D201 V206 H207 E208	M200-A204 PolarHBondContact O-N 2.65Å; D201-A204 PolarHBondContact O-N 3.12Å; A204-V206 VanDerWaalsContact C-N 3.34Å; A204-V206 PolarHBondContact O-N 3.47Å; A204-H207 PolarHBondContact O-N 3.5Å; A204-H207 VanDerWaalsContact O-N 3.15Å; A204-E208 WeakPolarHBondContact O-CB 3.41Å; A204-E208 PolarHBondContact O-N 2.9Å
205	L	98.5	Very high	96.8	Very high	54 Å²	54	56.4 Å²	56.4	28%	0.283	29%	0.29	S	S	.	.	H	α-helix	trans	-58.6	-41.5	176.9	-179.9	62.7	0	0	0	112.3	A189 D201 Y202 R203 H207 E208 R209	A189-L205 HydrophobicContact CB-CD2 3.9Å; A189-L205 HydrophobicContact CB-CG 3.95Å; D201-L205 VanDerWaalsContact O-CB 3.31Å; D201-L205 WeakPolarHBondContact O-CB 3.36Å; D201-L205 PolarHBondContact O-N 3.19Å; Y202-L205 HydrophobicContact CD1-CD2 4.3Å; R203-L205 VanDerWaalsContact C-N 3.3Å; R203-L205 PolarHBondContact O-N 3.33Å; L205-H207 VanDerWaalsContact C-N 3.33Å; L205-H207 PolarHBondContact O-N 2.84Å; L205-E208 PolarHBondContact O-N 3.44Å; L205-R209 HydrophobicContact CD1-CG 4.21Å; L205-R209 HydrophobicContact CG-CG 4.46Å; L205-R209 WeakPolarHBondContact O-CB 3.22Å; L205-R209 WeakPolarHBondContact O-CG 3.5Å; L205-R209 PolarHBondContact O-N 2.91Å
206	V	98.6	Very high	97.1	Very high	0 Å²	0	53.3 Å²	53.3	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-59.7	-45.7	176.4	172.3	0	0	0	0	110.9	L64 A189 V190 Y202 R203 A204 R209 D210	L64-V206 HydrophobicContact CD1-CG1 4.38Å; L64-V206 HydrophobicContact CD2-CB 4.07Å; L64-V206 HydrophobicContact CD2-CG1 4.26Å; L64-V206 HydrophobicContact CD2-CG2 4.17Å; A189-V206 HydrophobicContact CB-CG2 3.77Å; V190-V206 HydrophobicContact CB-CG2 4.41Å; V190-V206 HydrophobicContact CG2-CB 4.5Å; V190-V206 HydrophobicContact CG2-CG1 3.9Å; V190-V206 HydrophobicContact CG2-CG2 3.67Å; Y202-V206 WeakPolarHBondContact O-CG2 3.47Å; Y202-V206 PolarHBondContact O-N 3.22Å; Y202-V206 VanDerWaalsContact O-N 3.17Å; R203-V206 PolarHBondContact O-N 3.33Å; A204-V206 VanDerWaalsContact C-N 3.34Å; A204-V206 PolarHBondContact O-N 3.47Å; V206-R209 PolarHBondContact O-N 3.27Å; V206-D210 PolarHBondContact O-N 2.93Å
207	H	98.3	Very high	97.4	Very high	34 Å²	34	50.3 Å²	50.3	16%	0.157	26%	0.264	C	S	.	.	H	α-helix	trans	-68.4	-42	178.9	-62.1	-44.5	0	0	0	112.3	R61 A62 R203 A204 L205 R209 D210 E211	R61-H207 HydrophobicContact CG-CB 4.12Å; A62-H207 PolarHBondContact O-CE1 3.39Å; R203-H207 PolarHBondContact O-CD2 3.27Å; R203-H207 PolarHBondContact O-N 2.99Å; A204-H207 PolarHBondContact O-N 3.5Å; A204-H207 VanDerWaalsContact O-N 3.15Å; L205-H207 VanDerWaalsContact C-N 3.33Å; L205-H207 PolarHBondContact O-N 2.84Å; H207-R209 VanDerWaalsContact C-N 3.26Å; H207-R209 PolarHBondContact O-N 3.22Å; H207-D210 WeakPolarHBondContact O-CB 3.4Å; H207-D210 PolarHBondContact O-N 2.94Å; H207-E211 WeakPolarHBondContact O-CG 3.43Å; H207-E211 PolarHBondContact O-N 3.26Å
208	E	98.3	Very high	97.7	Very high	111 Å²	111	54.2 Å²	54.2	52%	0.519	28%	0.278	S	S	.	.	H	α-helix	trans	-60.3	-37.4	176.4	-171.1	62.2	-151.4	0	0	111.4	A204 L205 D210 E211 A212	A204-E208 WeakPolarHBondContact O-CB 3.41Å; A204-E208 PolarHBondContact O-N 2.9Å; L205-E208 PolarHBondContact O-N 3.44Å; E208-D210 VanDerWaalsContact C-N 3.32Å; E208-D210 PolarHBondContact O-N 2.89Å; E208-E211 PolarHBondContact O-N 3.11Å; E208-A212 VanDerWaalsContact O-CB 3.26Å; E208-A212 WeakPolarHBondContact O-CB 3.5Å; E208-A212 PolarHBondContact O-N 3.11Å
209	R	98.3	Very high	98	Very high	96 Å²	96	50.3 Å²	50.3	36%	0.362	27%	0.267	S	S	.	.	H	α-helix	trans	-65.3	-34.8	174.7	-68.8	-67.1	169.5	176.1	6.8	112.7	E185 L205 V206 H207 A213	E185-R209 IonicContact OE2-CZ 3.5Å; E185-R209 IonicContact OE2-NE 3.25Å; E185-R209 IonicContact OE2-NH1 2.97Å; E185-R209 PolarHBondContact OE2-NH1 2.91Å; E185-R209 IonicContact OE2-NH2 3.09Å; L205-R209 HydrophobicContact CD1-CG 4.21Å; L205-R209 HydrophobicContact CG-CG 4.46Å; L205-R209 WeakPolarHBondContact O-CB 3.22Å; L205-R209 WeakPolarHBondContact O-CG 3.5Å; L205-R209 PolarHBondContact O-N 2.91Å; V206-R209 PolarHBondContact O-N 3.27Å; H207-R209 VanDerWaalsContact C-N 3.26Å; H207-R209 PolarHBondContact O-N 3.22Å; R209-A213 VanDerWaalsContact O-CB 3.23Å; R209-A213 WeakPolarHBondContact O-CB 3.46Å; R209-A213 PolarHBondContact O-N 3.21Å
210	D	98.4	Very high	98.2	Very high	1 Å²	1	48.8 Å²	48.8	1%	0.005	26%	0.258	C	S	.	.	H	α-helix	trans	-70.6	-42.7	175.7	-71.5	-23.4	0	0	0	111.4	N112 V115 Y182 R186 V206 H207 E208 A213 Y214	N112-D210 WeakPolarHBondContact ND2-CB 3.43Å; N112-D210 PolarHBondContact ND2-OD2 3.45Å; V115-D210 HydrophobicContact CG2-CB 4.31Å; Y182-D210 PolarHBondContact OH-OD1 3.26Å; R186-D210 VanDerWaalsContact CD-OD1 3.29Å; R186-D210 WeakPolarHBondContact CD-OD1 3.33Å; R186-D210 IonicContact CZ-OD1 2.74Å; R186-D210 IonicContact CZ-OD2 3.91Å; R186-D210 IonicContact NE-OD1 3.44Å; R186-D210 PolarHBondContact NE-OD1 2.72Å; R186-D210 IonicContact NE-OD2 3.99Å; R186-D210 PolarHBondContact NE-OD2 3.16Å; R186-D210 IonicContact NH2-OD1 2.77Å; R186-D210 IonicContact NH2-OD2 2.68Å; R186-D210 PolarHBondContact NH2-OD2 3.15Å; V206-D210 PolarHBondContact O-N 2.93Å; H207-D210 WeakPolarHBondContact O-CB 3.4Å; H207-D210 PolarHBondContact O-N 2.94Å; E208-D210 VanDerWaalsContact C-N 3.32Å; E208-D210 PolarHBondContact O-N 2.89Å; D210-A213 PolarHBondContact O-N 2.68Å; D210-Y214 PolarHBondContact O-N 3.16Å; D210-Y214 VanDerWaalsContact O-N 3.08Å
211	E	98.3	Very high	98.3	Very high	27 Å²	27	44.2 Å²	44.2	13%	0.126	24%	0.235	C	C	.	.	H	α-helix	trans	-65.3	-43.9	176.9	-65.2	-176	-145.7	0	0	111.4	L57 R61 H207 E208 Y214 G215	L57-E211 HydrophobicContact CB-CG 4.06Å; L57-E211 HydrophobicContact CD1-CB 4.46Å; R61-E211 IonicContact CZ-OE1 4Å; R61-E211 IonicContact NE-OE1 3.57Å; R61-E211 PolarHBondContact NE-OE1 2.9Å; R61-E211 IonicContact NH2-OE1 2.63Å; R61-E211 PolarHBondContact NH2-OE1 2.74Å; R61-E211 VanDerWaalsContact NH2-OE1 3.09Å; H207-E211 WeakPolarHBondContact O-CG 3.43Å; H207-E211 PolarHBondContact O-N 3.26Å; E208-E211 PolarHBondContact O-N 3.11Å; E211-Y214 WeakPolarHBondContact O-CB 3.16Å; E211-Y214 PolarHBondContact O-N 3.19Å; E211-G215 PolarHBondContact O-N 3.46Å; E211-G215 VanDerWaalsContact O-N 3.16Å
212	A	98.1	Very high	98.4	Very high	42 Å²	42	40.9 Å²	40.9	35%	0.347	22%	0.217	S	C	.	.	H	α-helix	trans	-62	-46.2	175.4	0	0	0	0	0	112	E208 Y214 G215 E216	E208-A212 VanDerWaalsContact O-CB 3.26Å; E208-A212 WeakPolarHBondContact O-CB 3.5Å; E208-A212 PolarHBondContact O-N 3.11Å; A212-Y214 VanDerWaalsContact C-N 3.3Å; A212-Y214 PolarHBondContact O-N 3.48Å; A212-G215 PolarHBondContact O-N 3.28Å; A212-G215 VanDerWaalsContact O-N 3.15Å; A212-E216 WeakPolarHBondContact O-CG 3.5Å; A212-E216 PolarHBondContact O-N 2.76Å
213	A	98.3	Very high	98.4	Very high	5 Å²	5	40.7 Å²	40.7	4%	0.041	22%	0.221	C	C	.	.	H	α-helix	trans	-61.4	-38.8	178.7	0	0	0	0	0	112.2	V115 Y182 R209 D210 E216 L217	V115-A213 HydrophobicContact CG1-CB 4.15Å; Y182-A213 HydrophobicContact CD2-CB 3.4Å; Y182-A213 VanDerWaalsContact CD2-CB 3.4Å; Y182-A213 HydrophobicContact CE2-CB 3.54Å; Y182-A213 HydrophobicContact CG-CB 4.11Å; R209-A213 VanDerWaalsContact O-CB 3.23Å; R209-A213 WeakPolarHBondContact O-CB 3.46Å; R209-A213 PolarHBondContact O-N 3.21Å; D210-A213 PolarHBondContact O-N 2.68Å; A213-E216 PolarHBondContact O-N 2.91Å; A213-L217 WeakPolarHBondContact O-CB 3.39Å; A213-L217 WeakPolarHBondContact O-CD1 3.29Å; A213-L217 WeakPolarHBondContact O-CG 3.26Å; A213-L217 PolarHBondContact O-N 3.15Å
214	Y	98.6	Very high	98.4	Very high	10 Å²	10	39.5 Å²	39.5	4%	0.039	22%	0.216	C	C	.	.	H	α-helix	trans	-59.1	-49.2	172.9	168.4	-94.6	0	0	0	112	S51 L52 N53 V54 L57 L60 L118 D210 E211 A212 E216 L217 R218	S51-Y214 WeakPolarHBondContact O-CE2 3.48Å; L52-Y214 PolarHBondContact O-OH 3.39Å; N53-Y214 PolarHBondContact N-OH 3.48Å; V54-Y214 HydrophobicContact CB-CE1 4.35Å; V54-Y214 HydrophobicContact CB-CE2 4.14Å; V54-Y214 WeakPolarHBondContact CB-OH 3.36Å; V54-Y214 HydrophobicContact CG2-CE2 3.81Å; V54-Y214 PolarHBondContact N-OH 3.05Å; L57-Y214 HydrophobicContact CD2-CD1 3.52Å; L57-Y214 HydrophobicContact CD2-CE1 3.49Å; L57-Y214 VanDerWaalsContact CD2-CE1 3.49Å; L60-Y214 HydrophobicContact CD1-CD1 3.77Å; L60-Y214 HydrophobicContact CD1-CD2 3.81Å; L60-Y214 HydrophobicContact CD1-CE1 4.46Å; L60-Y214 HydrophobicContact CD1-CG 3.4Å; L60-Y214 HydrophobicContact CD2-CD2 4.16Å; L118-Y214 HydrophobicContact CD1-CD2 3.47Å; L118-Y214 VanDerWaalsContact CD1-CD2 3.47Å; L118-Y214 HydrophobicContact CD1-CE2 3.86Å; D210-Y214 PolarHBondContact O-N 3.16Å; D210-Y214 VanDerWaalsContact O-N 3.08Å; E211-Y214 WeakPolarHBondContact O-CB 3.16Å; E211-Y214 PolarHBondContact O-N 3.19Å; A212-Y214 VanDerWaalsContact C-N 3.3Å; A212-Y214 PolarHBondContact O-N 3.48Å; Y214-E216 VanDerWaalsContact C-N 3.32Å; Y214-E216 PolarHBondContact O-N 3.18Å; Y214-L217 PolarHBondContact O-N 3.39Å; Y214-R218 PolarHBondContact O-N 2.97Å
215	G	98.1	Very high	98.5	Very high	37 Å²	37	40 Å²	40	38%	0.381	21%	0.206	S	C	.	.	H	α-helix	trans	-58.9	-44.4	178.2	0	0	0	0	0	112.1	E211 A212 R218 A219	E211-G215 PolarHBondContact O-N 3.46Å; E211-G215 VanDerWaalsContact O-N 3.16Å; A212-G215 PolarHBondContact O-N 3.28Å; A212-G215 VanDerWaalsContact O-N 3.15Å; G215-R218 PolarHBondContact O-N 3.04Å; G215-A219 WeakPolarHBondContact O-CB 3.22Å; G215-A219 PolarHBondContact O-N 2.82Å
216	E	98.3	Very high	98.5	Very high	91 Å²	91	39.1 Å²	39.1	43%	0.425	21%	0.207	S	C	.	.	H	α-helix	trans	-62.2	-46.3	176	-71.9	-179.3	160.4	0	0	112.1	T178 A212 A213 Y214 R218 A219 M220	T178-E216 HydrophobicContact CG2-CB 4.49Å; T178-E216 HydrophobicContact CG2-CG 4.47Å; T178-E216 WeakPolarHBondContact CG2-OE2 3.25Å; A212-E216 WeakPolarHBondContact O-CG 3.5Å; A212-E216 PolarHBondContact O-N 2.76Å; A213-E216 PolarHBondContact O-N 2.91Å; Y214-E216 VanDerWaalsContact C-N 3.32Å; Y214-E216 PolarHBondContact O-N 3.18Å; E216-R218 VanDerWaalsContact C-N 3.34Å; E216-R218 PolarHBondContact O-N 2.93Å; E216-A219 PolarHBondContact O-N 3.43Å; E216-M220 HydrophobicContact CB-CE 4.34Å; E216-M220 VanDerWaalsContact O-CG 3.26Å; E216-M220 WeakPolarHBondContact O-CG 3.37Å; E216-M220 PolarHBondContact O-N 2.91Å
217	L	98.6	Very high	98.5	Very high	5 Å²	5	39.4 Å²	39.4	3%	0.026	21%	0.209	C	C	.	.	H	α-helix	trans	-62.6	-41.1	178.8	-71.6	166.8	0	0	0	111.8	V115 L118 L119 V122 I179 A213 Y214 M220 V221	V115-L217 HydrophobicContact CG1-CD1 4.08Å; L118-L217 HydrophobicContact CB-CD1 4.05Å; L119-L217 HydrophobicContact CD2-CD1 4.15Å; L119-L217 HydrophobicContact CD2-CD2 3.64Å; L119-L217 HydrophobicContact CD2-CG 4.48Å; L119-L217 HydrophobicContact CG-CD1 3.87Å; L119-L217 HydrophobicContact CG-CD2 4.21Å; V122-L217 HydrophobicContact CB-CD2 3.99Å; V122-L217 HydrophobicContact CG1-CD2 3.97Å; V122-L217 HydrophobicContact CG2-CB 4.38Å; V122-L217 HydrophobicContact CG2-CD2 4.21Å; I179-L217 HydrophobicContact CG1-CD2 4.41Å; A213-L217 WeakPolarHBondContact O-CB 3.39Å; A213-L217 WeakPolarHBondContact O-CD1 3.29Å; A213-L217 WeakPolarHBondContact O-CG 3.26Å; A213-L217 PolarHBondContact O-N 3.15Å; Y214-L217 PolarHBondContact O-N 3.39Å; L217-M220 HydrophobicContact CD2-SD 4.29Å; L217-M220 WeakPolarHBondContact O-CB 3.23Å; L217-M220 PolarHBondContact O-N 3.33Å; L217-V221 WeakPolarHBondContact O-CG2 3.34Å; L217-V221 PolarHBondContact O-N 3.27Å
218	R	98.4	Very high	98.5	Very high	87 Å²	87	37.8 Å²	37.8	33%	0.328	20%	0.201	S	C	.	.	H	α-helix	trans	-64.1	-43.9	175.1	-172.7	-179.8	-175.3	-83	-1.7	111.6	L52 Y214 G215 E216 M220 V221 L222	L52-R218 HydrophobicContact CD2-CB 4.04Å; L52-R218 HydrophobicContact CD2-CG 4.18Å; L52-R218 VanDerWaalsContact O-CD 3.22Å; L52-R218 WeakPolarHBondContact O-CD 3.34Å; L52-R218 PolarHBondContact O-NE 2.92Å; Y214-R218 PolarHBondContact O-N 2.97Å; G215-R218 PolarHBondContact O-N 3.04Å; E216-R218 VanDerWaalsContact C-N 3.34Å; E216-R218 PolarHBondContact O-N 2.93Å; R218-M220 VanDerWaalsContact C-N 3.32Å; R218-M220 PolarHBondContact O-N 2.86Å; R218-V221 PolarHBondContact O-N 3.43Å; R218-L222 PolarHBondContact O-N 2.89Å
219	A	98.6	Very high	98.5	Very high	43 Å²	43	34.6 Å²	34.6	36%	0.355	19%	0.194	S	C	.	.	H	α-helix	trans	-61.4	-40.7	175.6	0	0	0	0	0	111.7	G215 E216 V221 L222 D223	G215-A219 WeakPolarHBondContact O-CB 3.22Å; G215-A219 PolarHBondContact O-N 2.82Å; E216-A219 PolarHBondContact O-N 3.43Å; A219-V221 PolarHBondContact O-N 3.38Å; A219-L222 WeakPolarHBondContact O-CB 3.36Å; A219-L222 PolarHBondContact O-N 3.39Å; A219-D223 WeakPolarHBondContact O-CB 2.95Å; A219-D223 PolarHBondContact O-N 3.46Å
220	M	98.8	Very high	98.5	Very high	7 Å²	7	33.4 Å²	33.4	3%	0.034	19%	0.192	C	C	.	.	H	α-helix	trans	-57.7	-45.2	175.1	-71.4	175.3	-163.3	0	0	111.7	V122 F175 T178 I179 E216 L217 R218 L222 D223 L224	V122-M220 HydrophobicContact CG1-CB 4.18Å; V122-M220 HydrophobicContact CG1-SD 4.35Å; F175-M220 HydrophobicContact CB-CE 4.13Å; F175-M220 HydrophobicContact CB-CG 4.2Å; F175-M220 HydrophobicContact CB-SD 3.86Å; F175-M220 HydrophobicContact CD1-CE 4.23Å; F175-M220 HydrophobicContact CD1-CG 3.74Å; F175-M220 HydrophobicContact CD1-SD 4.37Å; F175-M220 HydrophobicContact CD2-CB 4.39Å; F175-M220 HydrophobicContact CD2-CG 4.06Å; F175-M220 HydrophobicContact CE1-CG 4.04Å; F175-M220 HydrophobicContact CE2-CB 4.45Å; F175-M220 HydrophobicContact CE2-CG 4.33Å; F175-M220 HydrophobicContact CG-CE 4.42Å; F175-M220 HydrophobicContact CG-CG 3.76Å; F175-M220 HydrophobicContact CG-SD 4.1Å; F175-M220 HydrophobicContact CZ-CG 4.33Å; T178-M220 HydrophobicContact CG2-CE 3.58Å; I179-M220 HydrophobicContact CD1-SD 4.08Å; I179-M220 HydrophobicContact CG1-CE 4.23Å; I179-M220 HydrophobicContact CG1-SD 4.11Å; E216-M220 HydrophobicContact CB-CE 4.34Å; E216-M220 VanDerWaalsContact O-CG 3.26Å; E216-M220 WeakPolarHBondContact O-CG 3.37Å; E216-M220 PolarHBondContact O-N 2.91Å; L217-M220 HydrophobicContact CD2-SD 4.29Å; L217-M220 WeakPolarHBondContact O-CB 3.23Å; L217-M220 PolarHBondContact O-N 3.33Å; R218-M220 VanDerWaalsContact C-N 3.32Å; R218-M220 PolarHBondContact O-N 2.86Å; M220-L222 VanDerWaalsContact C-N 3.33Å; M220-L222 PolarHBondContact O-N 3.25Å; M220-D223 PolarHBondContact O-N 2.68Å; M220-L224 WeakPolarHBondContact O-CB 3.22Å; M220-L224 WeakPolarHBondContact O-CG 3.16Å; M220-L224 PolarHBondContact O-N 3.04Å
221	V	98.8	Very high	98.5	Very high	0 Å²	0	33.4 Å²	33.4	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-63.8	-39.5	179.2	-178	0	0	0	0	111.6	L43 L46 L47 L52 V122 L217 R218 A219 R225	L43-V221 HydrophobicContact CD2-CG1 4.19Å; L46-V221 HydrophobicContact CD2-CG1 4.12Å; L46-V221 HydrophobicContact CD2-CG2 4.46Å; L46-V221 HydrophobicContact CG-CG1 4.48Å; L47-V221 HydrophobicContact CD1-CG1 4.16Å; L47-V221 HydrophobicContact CD2-CB 3.97Å; L47-V221 HydrophobicContact CD2-CG1 3.71Å; L47-V221 HydrophobicContact CG-CB 4.43Å; L47-V221 HydrophobicContact CG-CG1 3.62Å; L52-V221 HydrophobicContact CD1-CG2 4.33Å; V122-V221 HydrophobicContact CG1-CG2 4.39Å; V122-V221 HydrophobicContact CG2-CG2 3.63Å; L217-V221 WeakPolarHBondContact O-CG2 3.34Å; L217-V221 PolarHBondContact O-N 3.27Å; R218-V221 PolarHBondContact O-N 3.43Å; A219-V221 PolarHBondContact O-N 3.38Å; V221-R225 PolarHBondContact O-N 2.85Å; V221-R225 VanDerWaalsContact O-N 3.12Å
222	L	98.8	Very high	98.5	Very high	55 Å²	55	36.9 Å²	36.9	29%	0.288	21%	0.205	S	C	.	.	H	α-helix	trans	-60.9	-48.1	174	-71.9	166	0	0	0	111.5	L47 R218 A219 M220 R225 A226	L47-L222 HydrophobicContact CD1-CD2 3.65Å; L47-L222 HydrophobicContact CD1-CG 4.3Å; L47-L222 HydrophobicContact CD2-CD2 3.96Å; L47-L222 HydrophobicContact CD2-CG 3.95Å; L47-L222 HydrophobicContact CG-CD2 4.46Å; R218-L222 PolarHBondContact O-N 2.89Å; A219-L222 WeakPolarHBondContact O-CB 3.36Å; A219-L222 PolarHBondContact O-N 3.39Å; M220-L222 VanDerWaalsContact C-N 3.33Å; M220-L222 PolarHBondContact O-N 3.25Å; L222-R225 PolarHBondContact O-N 3.06Å; L222-A226 WeakPolarHBondContact O-CB 3.49Å; L222-A226 PolarHBondContact O-N 3Å
223	D	98.8	Very high	98.5	Very high	68 Å²	68	40.8 Å²	40.8	36%	0.364	22%	0.216	S	C	.	.	H	α-helix	trans	-65.9	-41.4	179.7	-79.8	-14.2	0	0	0	112	F175 A219 M220 R225 A226 F227	F175-D223 HydrophobicContact CE2-CB 4.1Å; F175-D223 HydrophobicContact CZ-CB 3.68Å; A219-D223 WeakPolarHBondContact O-CB 2.95Å; A219-D223 PolarHBondContact O-N 3.46Å; M220-D223 PolarHBondContact O-N 2.68Å; D223-R225 VanDerWaalsContact C-N 3.32Å; D223-R225 PolarHBondContact O-N 3.45Å; D223-A226 CarbonylContact O-C 3.59Å; D223-A226 WeakPolarHBondContact O-CB 3.33Å; D223-A226 PolarHBondContact O-N 2.89Å; D223-F227 HydrophobicContact CB-CE2 3.94Å; D223-F227 HydrophobicContact CB-CZ 4Å; D223-F227 WeakPolarHBondContact O-CB 3.35Å; D223-F227 VanDerWaalsContact O-CD2 3.25Å; D223-F227 WeakPolarHBondContact O-CD2 3.3Å; D223-F227 WeakPolarHBondContact O-CG 3.28Å; D223-F227 PolarHBondContact O-N 2.97Å
224	L	98.8	Very high	98.5	Very high	0 Å²	0	42.4 Å²	42.4	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-58	-45.9	175.2	-72	172.1	0	0	0	110.8	L43 E125 V126 L129 V172 F175 M220 F227 Y228	L43-L224 HydrophobicContact CD1-CB 4.02Å; E125-L224 HydrophobicContact CB-CD1 3.73Å; V126-L224 HydrophobicContact CG2-CD1 4.03Å; L129-L224 HydrophobicContact CB-CD2 4.03Å; L129-L224 HydrophobicContact CD2-CD2 3.46Å; L129-L224 VanDerWaalsContact CD2-CD2 3.46Å; L129-L224 HydrophobicContact CG-CD2 4.38Å; V172-L224 HydrophobicContact CG2-CD2 4.48Å; F175-L224 HydrophobicContact CD2-CD2 4.47Å; F175-L224 HydrophobicContact CE2-CD2 4.4Å; M220-L224 WeakPolarHBondContact O-CB 3.22Å; M220-L224 WeakPolarHBondContact O-CG 3.16Å; M220-L224 PolarHBondContact O-N 3.04Å; L224-F227 PolarHBondContact O-N 3.18Å; L224-Y228 WeakPolarHBondContact O-CD2 3.44Å; L224-Y228 PolarHBondContact O-N 2.76Å
225	R	98.8	Very high	98.5	Very high	66 Å²	66	42 Å²	42	25%	0.249	22%	0.221	C	C	.	.	H	α-helix	trans	-62.8	-43.6	176.1	-174.2	-176	63.3	-178.8	-4.9	111.2	I40 L43 N44 L47 V221 L222 D223 Y228 A229	I40-R225 HydrophobicContact CG2-CG 4.23Å; L43-R225 HydrophobicContact CB-CB 3.97Å; L43-R225 HydrophobicContact CB-CG 4.23Å; L43-R225 HydrophobicContact CD1-CB 4.08Å; N44-R225 PolarHBondContact OD1-NH1 3.43Å; L47-R225 VanDerWaalsContact CD1-CZ 3.46Å; V221-R225 PolarHBondContact O-N 2.85Å; V221-R225 VanDerWaalsContact O-N 3.12Å; L222-R225 PolarHBondContact O-N 3.06Å; D223-R225 VanDerWaalsContact C-N 3.32Å; D223-R225 PolarHBondContact O-N 3.45Å; R225-Y228 PolarHBondContact O-N 2.95Å; R225-A229 PolarHBondContact O-N 3.21Å; R225-A229 VanDerWaalsContact O-N 3.15Å
226	A	98.7	Very high	98.4	Very high	37 Å²	37	42.7 Å²	42.7	31%	0.306	22%	0.221	S	C	.	.	H	α-helix	trans	-61.9	-45.7	177.2	0	0	0	0	0	111.4	L222 D223 Y228 A229 E230	L222-A226 WeakPolarHBondContact O-CB 3.49Å; L222-A226 PolarHBondContact O-N 3Å; D223-A226 CarbonylContact O-C 3.59Å; D223-A226 WeakPolarHBondContact O-CB 3.33Å; D223-A226 PolarHBondContact O-N 2.89Å; A226-Y228 PolarHBondContact O-N 3.09Å; A226-A229 PolarHBondContact O-N 3.42Å; A226-A229 VanDerWaalsContact O-N 3.14Å; A226-E230 WeakPolarHBondContact O-CB 3.41Å; A226-E230 VanDerWaalsContact O-CG 3.27Å; A226-E230 WeakPolarHBondContact O-CG 3.41Å; A226-E230 PolarHBondContact O-N 2.83Å
227	F	98.8	Very high	98.4	Very high	6 Å²	6	41.7 Å²	41.7	3%	0.026	22%	0.224	C	C	.	.	H	α-helix	trans	-61.7	-42.2	178.5	-64.9	-26.2	0	0	0	112.4	L129 V168 K171 V172 F175 D223 L224 A229 E230 L231	L129-F227 HydrophobicContact CD2-CB 3.9Å; L129-F227 HydrophobicContact CD2-CD2 3.97Å; L129-F227 HydrophobicContact CD2-CG 4.45Å; V168-F227 HydrophobicContact CG1-CB 3.75Å; V168-F227 HydrophobicContact CG1-CD1 4.3Å; V168-F227 HydrophobicContact CG1-CD2 3.92Å; V168-F227 HydrophobicContact CG1-CG 3.73Å; V168-F227 HydrophobicContact CG2-CD1 4.11Å; V168-F227 HydrophobicContact CG2-CG 4.34Å; K171-F227 HydrophobicContact CB-CE2 4.08Å; K171-F227 HydrophobicContact CB-CZ 3.95Å; K171-F227 HydrophobicContact CD-CE1 3.89Å; K171-F227 HydrophobicContact CD-CE2 4.4Å; K171-F227 HydrophobicContact CD-CZ 3.47Å; K171-F227 VanDerWaalsContact CD-CZ 3.47Å; K171-F227 HydrophobicContact CG-CZ 4.39Å; V172-F227 HydrophobicContact CG2-CD2 4.21Å; V172-F227 HydrophobicContact CG2-CE2 4.4Å; F175-F227 AromaticContact CE2-CE2 3.83Å; F175-F227 HydrophobicContact CE2-CE2 3.83Å; F175-F227 AromaticContact CZ-CE2 3.96Å; F175-F227 HydrophobicContact CZ-CE2 3.96Å; F175-F227 HydrophobicContact CZ-CZ 4.44Å; D223-F227 HydrophobicContact CB-CE2 3.94Å; D223-F227 HydrophobicContact CB-CZ 4Å; D223-F227 WeakPolarHBondContact O-CB 3.35Å; D223-F227 VanDerWaalsContact O-CD2 3.25Å; D223-F227 WeakPolarHBondContact O-CD2 3.3Å; D223-F227 WeakPolarHBondContact O-CG 3.28Å; D223-F227 PolarHBondContact O-N 2.97Å; L224-F227 PolarHBondContact O-N 3.18Å; F227-A229 PolarHBondContact O-N 2.83Å; F227-E230 PolarHBondContact O-N 2.9Å; F227-L231 VanDerWaalsContact O-CB 3.28Å; F227-L231 WeakPolarHBondContact O-CB 3.32Å; F227-L231 WeakPolarHBondContact O-CG 3.23Å; F227-L231 PolarHBondContact O-N 3.04Å
228	Y	98.8	Very high	98.4	Very high	0 Å²	0	43.9 Å²	43.9	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-59	-47.4	173	-78.8	-62.2	0	0	0	111.3	F31 F35 L36 K39 L43 L129 L224 R225 A226 E230 L231 Y232	F31-Y228 HydrophobicContact CE2-CD1 4.46Å; F31-Y228 HydrophobicContact CE2-CE1 4.06Å; F31-Y228 HydrophobicContact CZ-CD1 4.49Å; F31-Y228 HydrophobicContact CZ-CE1 4.41Å; F35-Y228 HydrophobicContact CE1-CE1 4.32Å; L36-Y228 HydrophobicContact CD1-CD1 4.43Å; L36-Y228 WeakPolarHBondContact CD2-O 3.21Å; L36-Y228 HydrophobicContact CG-CD1 3.89Å; L36-Y228 HydrophobicContact CG-CG 4.45Å; K39-Y228 HydrophobicContact CB-CD2 4.19Å; K39-Y228 HydrophobicContact CB-CE1 4.45Å; K39-Y228 HydrophobicContact CB-CE2 4.04Å; K39-Y228 HydrophobicContact CB-CG 4.48Å; K39-Y228 HydrophobicContact CG-CE2 4.41Å; L43-Y228 HydrophobicContact CD1-CD2 3.68Å; L43-Y228 HydrophobicContact CD1-CE2 3.83Å; L129-Y228 HydrophobicContact CB-CE2 4.38Å; L129-Y228 HydrophobicContact CD1-CD1 3.88Å; L129-Y228 HydrophobicContact CD1-CE1 3.47Å; L129-Y228 VanDerWaalsContact CD1-CE1 3.47Å; L129-Y228 HydrophobicContact CD1-CE2 4.22Å; L129-Y228 HydrophobicContact CD1-CG 4.44Å; L224-Y228 WeakPolarHBondContact O-CD2 3.44Å; L224-Y228 PolarHBondContact O-N 2.76Å; R225-Y228 PolarHBondContact O-N 2.95Å; A226-Y228 PolarHBondContact O-N 3.09Å; Y228-E230 PolarHBondContact O-N 2.97Å; Y228-L231 PolarHBondContact O-N 3.47Å; Y228-Y232 PolarHBondContact O-N 3.15Å
229	A	98.4	Very high	98.3	Very high	44 Å²	44	42.3 Å²	42.3	36%	0.364	23%	0.233	S	C	.	.	H	α-helix	trans	-61.9	-42.6	178.5	0	0	0	0	0	112.8	I40 R225 A226 F227 Y232 H233	I40-A229 HydrophobicContact CD1-CB 4Å; R225-A229 PolarHBondContact O-N 3.21Å; R225-A229 VanDerWaalsContact O-N 3.15Å; A226-A229 PolarHBondContact O-N 3.42Å; A226-A229 VanDerWaalsContact O-N 3.14Å; F227-A229 PolarHBondContact O-N 2.83Å; A229-Y232 PolarHBondContact O-N 3.34Å; A229-H233 WeakPolarHBondContact O-CB 3.32Å; A229-H233 PolarHBondContact O-N 3.46Å
230	E	98.3	Very high	98.2	Very high	71 Å²	71	45.3 Å²	45.3	33%	0.332	24%	0.24	S	C	.	.	H	α-helix	trans	-64.6	-45	176.9	-72.5	173.9	173.7	0	0	112.3	R164 A226 F227 Y228 H233 I234	R164-E230 IonicContact CZ-OE2 3.33Å; R164-E230 IonicContact NE-OE2 3.76Å; R164-E230 VanDerWaalsContact NH2-CD 3.26Å; R164-E230 IonicContact NH2-OE1 3.39Å; R164-E230 PolarHBondContact NH2-OE1 3.08Å; R164-E230 IonicContact NH2-OE2 2.77Å; R164-E230 PolarHBondContact NH2-OE2 2.78Å; A226-E230 WeakPolarHBondContact O-CB 3.41Å; A226-E230 VanDerWaalsContact O-CG 3.27Å; A226-E230 WeakPolarHBondContact O-CG 3.41Å; A226-E230 PolarHBondContact O-N 2.83Å; F227-E230 PolarHBondContact O-N 2.9Å; Y228-E230 PolarHBondContact O-N 2.97Å; E230-H233 PolarHBondContact O-N 3.47Å; E230-I234 WeakPolarHBondContact O-CG2 3.26Å; E230-I234 PolarHBondContact O-N 3.26Å
231	L	98.6	Very high	98.1	Very high	1 Å²	1	48.9 Å²	48.9	1%	0.005	26%	0.256	C	S	.	.	H	α-helix	trans	-61.7	-44.8	177.6	-74.4	174.4	0	0	0	110.7	L36 L129 V165 V168 F227 Y228 I234 I235	L36-L231 HydrophobicContact CD1-CB 4.46Å; L129-L231 HydrophobicContact CD1-CD1 4.05Å; V165-L231 HydrophobicContact CB-CD2 4.28Å; V165-L231 HydrophobicContact CG1-CD2 4.27Å; V165-L231 HydrophobicContact CG2-CD2 3.78Å; V168-L231 HydrophobicContact CG1-CD1 4.27Å; V168-L231 HydrophobicContact CG2-CD2 4.34Å; F227-L231 VanDerWaalsContact O-CB 3.28Å; F227-L231 WeakPolarHBondContact O-CB 3.32Å; F227-L231 WeakPolarHBondContact O-CG 3.23Å; F227-L231 PolarHBondContact O-N 3.04Å; Y228-L231 PolarHBondContact O-N 3.47Å; L231-I234 WeakPolarHBondContact O-CG2 3.16Å; L231-I235 VanDerWaalsContact O-CB 3.28Å; L231-I235 WeakPolarHBondContact O-CB 3.42Å; L231-I235 WeakPolarHBondContact O-CD1 3.47Å; L231-I235 WeakPolarHBondContact O-CG1 3.49Å; L231-I235 PolarHBondContact O-N 3.44Å
232	Y	97.9	Very high	98.1	Very high	99 Å²	99	48.9 Å²	48.9	39%	0.388	26%	0.256	S	S	.	.	H	α-helix	trans	-59.8	-51	174.7	-175.9	-94	0	0	0	111.1	L36 P37 Y228 A229 I234 I235 S236	L36-Y232 HydrophobicContact CD1-CD2 4.29Å; L36-Y232 HydrophobicContact CD2-CD2 3.95Å; L36-Y232 HydrophobicContact CD2-CG 4.03Å; P37-Y232 HydrophobicContact CG-CE2 4.34Å; Y228-Y232 PolarHBondContact O-N 3.15Å; A229-Y232 PolarHBondContact O-N 3.34Å; Y232-I234 PolarHBondContact O-N 3.17Å; Y232-I235 PolarHBondContact O-N 2.8Å; Y232-S236 VanDerWaalsContact O-CB 3.23Å; Y232-S236 WeakPolarHBondContact O-CB 3.35Å; Y232-S236 PolarHBondContact O-N 2.96Å; Y232-S236 PolarHBondContact O-OG 2.91Å
233	H	98.3	Very high	98	Very high	125 Å²	125	50 Å²	50	58%	0.579	26%	0.264	S	S	*	.	H	α-helix	trans	-58.9	-48.9	-177.6	177.1	62.9	0	0	0	112.4	A229 E230 S236 S237	A229-H233 WeakPolarHBondContact O-CB 3.32Å; A229-H233 PolarHBondContact O-N 3.46Å; E230-H233 PolarHBondContact O-N 3.47Å; H233-S236 PolarHBondContact O-OG 3.39Å; H233-S237 PolarHBondContact CE1-OG 3.49Å; H233-S237 WeakPolarHBondContact O-CB 3.37Å; H233-S237 PolarHBondContact O-N 3.37Å; H233-S237 PolarHBondContact O-OG 2.83Å
234	I	98.4	Very high	97.9	Very high	38 Å²	38	48 Å²	48	20%	0.195	25%	0.253	C	S	.	.	H	α-helix	trans	-69	-37.4	-178	-163.6	176.8	0	0	0	111.7	V161 R164 E230 L231 Y232 N238	V161-I234 HydrophobicContact CG2-CD1 4.39Å; V161-I234 HydrophobicContact CG2-CG1 4.27Å; R164-I234 HydrophobicContact CB-CD1 3.81Å; R164-I234 HydrophobicContact CG-CD1 3.94Å; E230-I234 WeakPolarHBondContact O-CG2 3.26Å; E230-I234 PolarHBondContact O-N 3.26Å; L231-I234 WeakPolarHBondContact O-CG2 3.16Å; Y232-I234 PolarHBondContact O-N 3.17Å; I234-N238 WeakPolarHBondContact O-CB 3.31Å; I234-N238 PolarHBondContact O-N 2.86Å; I234-N238 PolarHBondContact O-ND2 3.29Å
235	I	98	Very high	97.7	Very high	1 Å²	1	48.3 Å²	48.3	1%	0.005	26%	0.256	C	S	.	.	H	α-helix	trans	-71.8	-49.1	179.1	-65.5	167.2	0	0	0	110.1	L32 V136 W139 V161 L231 Y232 S237 N238 L239 I242	L32-I235 HydrophobicContact CD1-CG2 3.83Å; L32-I235 HydrophobicContact CD2-CB 4.3Å; L32-I235 HydrophobicContact CD2-CD1 3.87Å; L32-I235 HydrophobicContact CD2-CG2 3.85Å; V136-I235 HydrophobicContact CG1-CD1 3.83Å; W139-I235 HydrophobicContact CH2-CG2 4.33Å; W139-I235 HydrophobicContact CZ3-CG2 4.15Å; V161-I235 HydrophobicContact CG1-CG1 4.22Å; L231-I235 VanDerWaalsContact O-CB 3.28Å; L231-I235 WeakPolarHBondContact O-CB 3.42Å; L231-I235 WeakPolarHBondContact O-CD1 3.47Å; L231-I235 WeakPolarHBondContact O-CG1 3.49Å; L231-I235 PolarHBondContact O-N 3.44Å; Y232-I235 PolarHBondContact O-N 2.8Å; I235-S237 VanDerWaalsContact C-N 3.33Å; I235-S237 PolarHBondContact O-N 3.36Å; I235-N238 CarbonylContact O-C 3.5Å; I235-N238 PolarHBondContact O-N 3.18Å; I235-L239 HydrophobicContact CG2-CD1 4.27Å; I235-L239 WeakPolarHBondContact O-CA 3.35Å; I235-L239 WeakPolarHBondContact O-CB 3.37Å; I235-L239 PolarHBondContact O-N 3.07Å; I235-I242 HydrophobicContact CB-CD1 4.44Å; I235-I242 HydrophobicContact CG2-CD1 4.14Å
236	S	96.7	Very high	97.5	Very high	53 Å²	53	46.5 Å²	46.5	37%	0.371	25%	0.25	S	C	.	.	H	α-helix	trans	-63.3	-39.7	-177.9	70.2	0	0	0	0	111.9	Y232 H233 N238 L239	Y232-S236 VanDerWaalsContact O-CB 3.23Å; Y232-S236 WeakPolarHBondContact O-CB 3.35Å; Y232-S236 PolarHBondContact O-N 2.96Å; Y232-S236 PolarHBondContact O-OG 2.91Å; H233-S236 PolarHBondContact O-OG 3.39Å; S236-N238 PolarHBondContact O-N 3.36Å; S236-L239 PolarHBondContact O-N 3.34Å
237	S	97.8	Very high	97.2	Very high	70 Å²	70	46.9 Å²	46.9	49%	0.49	26%	0.258	S	S	.	.	H	α-helix	trans	-68.7	-22.6	-179.4	-56.1	0	0	0	0	113	H233 I235	H233-S237 PolarHBondContact CE1-OG 3.49Å; H233-S237 WeakPolarHBondContact O-CB 3.37Å; H233-S237 PolarHBondContact O-N 3.37Å; H233-S237 PolarHBondContact O-OG 2.83Å; I235-S237 VanDerWaalsContact C-N 3.33Å; I235-S237 PolarHBondContact O-N 3.36Å
238	N	97.9	Very high	96.6	Very high	51 Å²	51	53.2 Å²	53.2	27%	0.273	29%	0.287	S	S	.	.	T	Hydrogen-bonded Turn	trans	-116.5	10.6	-176.7	-62.8	-76.3	0	0	0	112.8	I157 V161 I234 I235 S236 E240 K241 I242	I157-N238 HydrophobicContact CG2-CB 3.88Å; V161-N238 HydrophobicContact CG2-CB 4.39Å; I234-N238 WeakPolarHBondContact O-CB 3.31Å; I234-N238 PolarHBondContact O-N 2.86Å; I234-N238 PolarHBondContact O-ND2 3.29Å; I235-N238 CarbonylContact O-C 3.5Å; I235-N238 PolarHBondContact O-N 3.18Å; S236-N238 PolarHBondContact O-N 3.36Å; N238-E240 VanDerWaalsContact C-N 3.34Å; N238-E240 PolarHBondContact O-N 2.71Å; N238-K241 PolarHBondContact O-N 3.25Å; N238-I242 HydrophobicContact CB-CD1 3.99Å; N238-I242 HydrophobicContact CB-CG1 4.24Å; N238-I242 WeakPolarHBondContact O-CG1 3.47Å; N238-I242 PolarHBondContact O-N 3.27Å
239	L	96.8	Very high	95.7	Very high	53 Å²	53	62.2 Å²	62.2	28%	0.277	33%	0.329	S	S	.	.	H	α-helix	trans	-57.6	-42.6	-166.1	-172.8	63.1	0	0	0	113.2	W139 I235 S236 K241 I242 V243	W139-L239 HydrophobicContact CH2-CD1 4.11Å; I235-L239 HydrophobicContact CG2-CD1 4.27Å; I235-L239 WeakPolarHBondContact O-CA 3.35Å; I235-L239 WeakPolarHBondContact O-CB 3.37Å; I235-L239 PolarHBondContact O-N 3.07Å; S236-L239 PolarHBondContact O-N 3.34Å; L239-K241 VanDerWaalsContact C-N 3.31Å; L239-K241 PolarHBondContact O-N 3.39Å; L239-I242 PolarHBondContact O-N 3.28Å; L239-V243 HydrophobicContact CD1-CG2 4.01Å; L239-V243 HydrophobicContact CG-CG2 4.43Å; L239-V243 WeakPolarHBondContact O-CG2 3.49Å; L239-V243 PolarHBondContact O-N 2.95Å
240	E	96.5	Very high	93.9	Very high	107 Å²	107	67.8 Å²	67.8	50%	0.5	35%	0.345	S	S	.	.	H	α-helix	trans	-60.7	-40.9	178.8	-176	60.2	-157.4	0	0	111.7	N238 N244	N238-E240 VanDerWaalsContact C-N 3.34Å; N238-E240 PolarHBondContact O-N 2.71Å; E240-N244 CarbonylContact O-C 3.5Å; E240-N244 WeakPolarHBondContact O-CA 3.42Å; E240-N244 WeakPolarHBondContact O-CB 3.24Å; E240-N244 PolarHBondContact O-N 2.69Å
241	K	97.3	Very high	91.5	Very high	82 Å²	82	69.8 Å²	69.8	36%	0.357	36%	0.364	S	S	.	.	H	α-helix	trans	-78.5	-26.2	178.2	-66.4	-59.9	-174.2	-174	0	113	I157 N238 L239 P245	I157-K241 HydrophobicContact CB-CB 4.36Å; I157-K241 HydrophobicContact CD1-CB 3.83Å; I157-K241 HydrophobicContact CD1-CG 3.79Å; I157-K241 HydrophobicContact CG2-CB 4.09Å; N238-K241 PolarHBondContact O-N 3.25Å; L239-K241 VanDerWaalsContact C-N 3.31Å; L239-K241 PolarHBondContact O-N 3.39Å; K241-P245 VanDerWaalsContact O-CA 3.29Å; K241-P245 WeakPolarHBondContact O-CA 3.4Å; K241-P245 WeakPolarHBondContact O-CB 3.31Å
242	I	97.3	Very high	88.5	Confident	0 Å²	0	74.2 Å²	74.2	0%	0	40%	0.396	C	S	.	.	H	α-helix	trans	-68.4	-44.7	172.4	-68.2	166.1	0	0	0	110.5	W139 I140 L143 Q158 V161 I235 N238 L239	W139-I242 HydrophobicContact CH2-CG2 3.97Å; W139-I242 HydrophobicContact CZ3-CG2 4.24Å; I140-I242 HydrophobicContact CG1-CG2 4.17Å; L143-I242 HydrophobicContact CD1-CG2 3.83Å; Q158-I242 PolarHBondContact NE2-O 3.25Å; V161-I242 HydrophobicContact CB-CD1 4.49Å; V161-I242 HydrophobicContact CG1-CD1 4.1Å; V161-I242 HydrophobicContact CG2-CD1 4.03Å; V161-I242 HydrophobicContact CG2-CG1 4.28Å; I235-I242 HydrophobicContact CB-CD1 4.44Å; I235-I242 HydrophobicContact CG2-CD1 4.14Å; N238-I242 HydrophobicContact CB-CD1 3.99Å; N238-I242 HydrophobicContact CB-CG1 4.24Å; N238-I242 WeakPolarHBondContact O-CG1 3.47Å; N238-I242 PolarHBondContact O-N 3.27Å; L239-I242 PolarHBondContact O-N 3.28Å
243	V	96.8	Very high	85.7	Confident	77 Å²	77	78.4 Å²	78.4	47%	0.467	42%	0.421	S	S	.	.	H	α-helix	trans	-86.2	-36.1	-175.1	177.7	0	0	0	0	112.5	W139 L143 L239	W139-V243 HydrophobicContact CZ2-CG2 4.24Å; L143-V243 HydrophobicContact CD1-CG2 4.33Å; L239-V243 HydrophobicContact CD1-CG2 4.01Å; L239-V243 HydrophobicContact CG-CG2 4.43Å; L239-V243 WeakPolarHBondContact O-CG2 3.49Å; L239-V243 PolarHBondContact O-N 2.95Å
244	N	96.3	Very high	82.8	Confident	26 Å²	26	86 Å²	86	14%	0.139	45%	0.446	C	S	.	.			trans	-128.6	67.4	-178.2	-170.7	12.2	0	0	0	111.5	E240 K246 G247 E248	E240-N244 CarbonylContact O-C 3.5Å; E240-N244 WeakPolarHBondContact O-CA 3.42Å; E240-N244 WeakPolarHBondContact O-CB 3.24Å; E240-N244 PolarHBondContact O-N 2.69Å; N244-K246 VanDerWaalsContact C-N 3.28Å; N244-K246 PolarHBondContact O-N 3.05Å; N244-G247 PolarHBondContact O-N 3.36Å; N244-G247 WeakPolarHBondContact OD1-CA 3.41Å; N244-G247 PolarHBondContact OD1-N 3.31Å; N244-G247 VanDerWaalsContact OD1-N 3.14Å; N244-E248 PolarHBondContact ND2-N 3.47Å; N244-E248 PolarHBondContact ND2-O 3.25Å; N244-E248 PolarHBondContact OD1-N 2.9Å
245	P	95.9	Very high	82	Confident	8 Å²	8	88.4 Å²	88.4	5%	0.052	46%	0.459	C	S	.	.	T	Hydrogen-bonded Turn	trans	-64	-30.7	-173.5	24.8	-34.8	0	0	0	113.5	P145 V155 K241	P145-P245 HydrophobicContact CG-CG 3.91Å; V155-P245 HydrophobicContact CG2-CB 4.33Å; K241-P245 VanDerWaalsContact O-CA 3.29Å; K241-P245 WeakPolarHBondContact O-CA 3.4Å; K241-P245 WeakPolarHBondContact O-CB 3.31Å
246	K	94.9	Very high	81.1	Confident	27 Å²	27	92.9 Å²	92.9	12%	0.117	48%	0.483	C	S	.	.	T	Hydrogen-bonded Turn	trans	-91.6	-8.2	-179.3	-64.1	-66.3	-176.7	-178.4	0	113.6	P145 G150 N151 D152 N244 E248	P145-K246 HydrophobicContact CB-CG 4.42Å; P145-K246 HydrophobicContact CG-CG 4.08Å; G150-K246 PolarHBondContact O-NZ 3.26Å; N151-K246 VanDerWaalsContact C-NZ 3.34Å; N151-K246 HydrophobicContact CB-CD 4.13Å; N151-K246 PolarHBondContact ND2-O 3.05Å; N151-K246 VanDerWaalsContact O-CD 3.31Å; N151-K246 WeakPolarHBondContact O-CD 3.36Å; N151-K246 WeakPolarHBondContact O-CE 3.24Å; N151-K246 PolarHBondContact O-NZ 3.48Å; D152-K246 IonicContact OD1-NZ 3.41Å; D152-K246 PolarHBondContact OD1-NZ 3.28Å; N244-K246 VanDerWaalsContact C-N 3.28Å; N244-K246 PolarHBondContact O-N 3.05Å; K246-E248 HydrophobicContact CB-CG 4.42Å
247	G	90.6	Very high	80.3	Confident	46 Å²	46	95.2 Å²	95.2	47%	0.474	49%	0.489	S	S	.	.			trans	71.7	33.1	178.5	0	0	0	0	0	113.3	N244	N244-G247 PolarHBondContact O-N 3.36Å; N244-G247 WeakPolarHBondContact OD1-CA 3.41Å; N244-G247 PolarHBondContact OD1-N 3.31Å; N244-G247 VanDerWaalsContact OD1-N 3.14Å
248	E	86.8	Confident	79.2	Confident	139 Å²	139	96.6 Å²	96.6	65%	0.65	49%	0.489	S	S	*	.	P	Polyproline II helix	trans	-61.3	137.3	175.1	-64.2	-179.8	-176.1	0	0	109.3	N244 K246 K250	N244-E248 PolarHBondContact ND2-N 3.47Å; N244-E248 PolarHBondContact ND2-O 3.25Å; N244-E248 PolarHBondContact OD1-N 2.9Å; K246-E248 HydrophobicContact CB-CG 4.42Å; E248-K250 PolarHBondContact O-N 2.81Å
249	E	80.6	Confident	78.1	Confident	188 Å²	188	99.5 Å²	99.5	88%	0.879	50%	0.502	S	S	*	.	P	Polyproline II helix	trans	-60.1	125.2	173.8	-67.8	-173.9	170.3	0	0	108.3	P251	E249-P251 VanDerWaalsContact O-N 3.15Å
250	K	60.9	Low	76.8	Confident	162 Å²	162	102.6 Å²	102.6	70%	0.704	52%	0.517	S	S	*	.	P	Polyproline II helix	trans	-53	126.8	169.7	-74.5	-179.3	-179.4	173.3	0	106.5	E248 S252	E248-K250 PolarHBondContact O-N 2.81Å; K250-S252 PolarHBondContact O-N 3.15Å
251	P	47.4	Very low	75.4	Confident	113 Å²	113	102.3 Å²	102.3	73%	0.734	52%	0.519	S	S	*	.	P	Polyproline II helix	trans	-51.8	123.8	174.3	3.1	-6.7	0	0	0	107.2	E249 M253	E249-P251 VanDerWaalsContact O-N 3.15Å; P251-M253 VanDerWaalsContact C-N 3.33Å; P251-M253 PolarHBondContact O-N 3.18Å
252	S	35.5	Very low	73.7	Confident	94 Å²	94	103.8 Å²	103.8	66%	0.657	53%	0.531	S	S	*	.			trans	-54.8	101.3	177.1	175.2	0	0	0	0	107.5	K250 Y254	K250-S252 PolarHBondContact O-N 3.15Å; S252-Y254 VanDerWaalsContact C-N 3.27Å; S252-Y254 PolarHBondContact O-N 3.13Å; S252-Y254 VanDerWaalsContact OG-CD2 3.25Å; S252-Y254 WeakPolarHBondContact OG-CD2 3.42Å; S252-Y254 VanDerWaalsContact OG-CE2 3.29Å; S252-Y254 WeakPolarHBondContact OG-CE2 3.09Å
253	M	39.4	Very low	71.8	Confident	186 Å²	186	112.5 Å²	112.5	92%	0.916	58%	0.575	S	S	*	*			trans	-74.4	89.1	171.6	-72.4	-88.3	-97.4	0	0	106.1	P251	P251-M253 VanDerWaalsContact C-N 3.33Å; P251-M253 PolarHBondContact O-N 3.18Å
254	Y	36.1	Very low	69.5	Low	284 Å²	284	115.7 Å²	115.7	100%	1.114	59%	0.585	S	S	*	*			trans	-81.5	0	152.2	-82.1	-80.6	0	0	0	109	S252	S252-Y254 VanDerWaalsContact C-N 3.27Å; S252-Y254 PolarHBondContact O-N 3.13Å; S252-Y254 VanDerWaalsContact OG-CD2 3.25Å; S252-Y254 WeakPolarHBondContact OG-CD2 3.42Å; S252-Y254 VanDerWaalsContact OG-CE2 3.29Å; S252-Y254 WeakPolarHBondContact OG-CE2 3.09Å

Retrieved 254 of 254 residues in 276.9 ms (Link to these results)

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