A0A3Q0KCT7_SCHMA Loading...

Proteasome activator PA28-gamma

Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.

AlphaFold DB (C1LZ83), UniProt , Accession A0A3Q0KCT7, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 250 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	50.6	Low	88.6	Confident	233 Å²	233	109.5 Å²	109.5	100%	1.148	58%	0.576	S	S	*	*				0	115.3	0	-67.8	176.9	-164.9	0	0	106.9	T3	M1-T3 PolarHBondContact O-N 3.04Å
2	N	67.6	Low	89.3	Confident	139 Å²	139	106.3 Å²	106.3	74%	0.743	55%	0.553	S	S	*	*			trans	-64.7	108.3	173.5	-89.2	-5.3	0	0	0	107.7	R7	N2-R7 HydrophobicContact CB-CG 4.07Å
3	T	89.9	Confident	89.9	Confident	90 Å²	90	106.4 Å²	106.4	55%	0.552	55%	0.55	S	S	*	.			trans	-59.9	149.1	170.7	58.3	0	0	0	0	108.4	M1 V5 G6 R7	M1-T3 PolarHBondContact O-N 3.04Å; T3-V5 PolarHBondContact O-N 3.38Å; T3-V5 VanDerWaalsContact O-N 3.12Å; T3-G6 WeakPolarHBondContact O-CA 3.44Å; T3-G6 PolarHBondContact O-N 3.09Å; T3-G6 PolarHBondContact OG1-N 3.37Å; T3-G6 VanDerWaalsContact OG1-N 3.17Å; T3-R7 PolarHBondContact O-N 3.12Å; T3-R7 VanDerWaalsContact O-N 3.09Å
4	E	94.8	Very high	90.4	Very high	129 Å²	129	108 Å²	108	60%	0.603	55%	0.55	S	S	*	*	H	α-helix	trans	-54.6	-32.1	175.2	-67	-56.3	137.1	0	0	111.6	R7 L8	E4-R7 PolarHBondContact O-N 3.02Å; E4-R7 IonicContact OE1-NH1 2.95Å; E4-R7 PolarHBondContact OE1-NH1 3.21Å; E4-R7 IonicContact OE2-CZ 3.72Å; E4-R7 IonicContact OE2-NH1 2.98Å; E4-R7 PolarHBondContact OE2-NH1 3.05Å; E4-L8 WeakPolarHBondContact O-CB 3.4Å; E4-L8 PolarHBondContact O-N 3.24Å
5	V	94.5	Very high	90.9	Very high	95 Å²	95	101.1 Å²	101.1	58%	0.576	52%	0.515	S	S	*	.	H	α-helix	trans	-61.5	-44.2	171.7	-179.3	0	0	0	0	112.2	T3 L8 N9	T3-V5 PolarHBondContact O-N 3.38Å; T3-V5 VanDerWaalsContact O-N 3.12Å; V5-L8 PolarHBondContact O-N 3.27Å; V5-N9 PolarHBondContact O-N 3.3Å
6	G	95.7	Very high	91.3	Very high	30 Å²	30	97.8 Å²	97.8	31%	0.309	50%	0.496	S	S	.	.	H	α-helix	trans	-63.6	-40.9	176.9	0	0	0	0	0	112.6	T3 N9 A10	T3-G6 WeakPolarHBondContact O-CA 3.44Å; T3-G6 PolarHBondContact O-N 3.09Å; T3-G6 PolarHBondContact OG1-N 3.37Å; T3-G6 VanDerWaalsContact OG1-N 3.17Å; G6-N9 PolarHBondContact O-N 3.17Å; G6-A10 PolarHBondContact O-N 2.87Å
7	R	96.4	Very high	91.6	Very high	141 Å²	141	97.8 Å²	97.8	53%	0.532	50%	0.502	S	S	.	.	H	α-helix	trans	-62.6	-43.1	174.8	-65.1	174.7	64.3	-162.9	0.5	111.6	N2 T3 E4 A10 Y11	N2-R7 HydrophobicContact CB-CG 4.07Å; T3-R7 PolarHBondContact O-N 3.12Å; T3-R7 VanDerWaalsContact O-N 3.09Å; E4-R7 PolarHBondContact O-N 3.02Å; E4-R7 IonicContact OE1-NH1 2.95Å; E4-R7 PolarHBondContact OE1-NH1 3.21Å; E4-R7 IonicContact OE2-CZ 3.72Å; E4-R7 IonicContact OE2-NH1 2.98Å; E4-R7 PolarHBondContact OE2-NH1 3.05Å; R7-A10 PolarHBondContact O-N 2.85Å; R7-Y11 PolarHBondContact O-N 3.45Å
8	L	96.1	Very high	92	Very high	86 Å²	86	95.8 Å²	95.8	45%	0.45	49%	0.493	S	S	.	.	H	α-helix	trans	-63.9	-41.3	177.2	179.2	60.4	0	0	0	112.1	E4 V5 Y11 K12	E4-L8 WeakPolarHBondContact O-CB 3.4Å; E4-L8 PolarHBondContact O-N 3.24Å; V5-L8 PolarHBondContact O-N 3.27Å; L8-Y11 HydrophobicContact CD1-CD1 4.43Å; L8-Y11 WeakPolarHBondContact O-CB 3.4Å; L8-Y11 PolarHBondContact O-N 2.82Å; L8-K12 WeakPolarHBondContact O-CG 3.47Å; L8-K12 PolarHBondContact O-N 3.01Å
9	N	95.8	Very high	92.3	Very high	82 Å²	82	90.8 Å²	90.8	44%	0.439	47%	0.467	S	S	.	.	H	α-helix	trans	-65.2	-42.5	177.1	-72.6	-18.3	0	0	0	111.8	V5 G6 Y11 K12 E13	V5-N9 PolarHBondContact O-N 3.3Å; G6-N9 PolarHBondContact O-N 3.17Å; N9-Y11 VanDerWaalsContact C-N 3.31Å; N9-Y11 PolarHBondContact O-N 2.8Å; N9-K12 PolarHBondContact O-N 3.05Å; N9-E13 PolarHBondContact O-N 2.99Å
10	A	96.4	Very high	92.5	Very high	64 Å²	64	88.6 Å²	88.6	53%	0.529	45%	0.454	S	S	.	.	H	α-helix	trans	-61.7	-39.6	174.5	0	0	0	0	0	112.1	G6 R7 K14	G6-A10 PolarHBondContact O-N 2.87Å; R7-A10 PolarHBondContact O-N 2.85Å; A10-K14 WeakPolarHBondContact O-CB 3.42Å; A10-K14 PolarHBondContact O-N 3.25Å
11	Y	96.9	Very high	92.7	Very high	116 Å²	116	89 Å²	89	46%	0.455	45%	0.454	S	S	.	.	H	α-helix	trans	-60.5	-47.9	173.4	173.3	-99	0	0	0	111.8	R7 L8 N9 E13 K14 T15 F138	R7-Y11 PolarHBondContact O-N 3.45Å; L8-Y11 HydrophobicContact CD1-CD1 4.43Å; L8-Y11 WeakPolarHBondContact O-CB 3.4Å; L8-Y11 PolarHBondContact O-N 2.82Å; N9-Y11 VanDerWaalsContact C-N 3.31Å; N9-Y11 PolarHBondContact O-N 2.8Å; Y11-E13 PolarHBondContact O-N 3.43Å; Y11-K14 PolarHBondContact O-N 2.96Å; Y11-T15 WeakPolarHBondContact O-CB 3.48Å; Y11-T15 PolarHBondContact O-N 2.98Å; Y11-T15 PolarHBondContact O-OG1 2.75Å; Y11-F138 HydrophobicContact CD1-CE2 4.37Å; Y11-F138 HydrophobicContact CD1-CZ 4.4Å; Y11-F138 HydrophobicContact CE1-CE2 4.04Å; Y11-F138 HydrophobicContact CE1-CZ 4.04Å
12	K	97	Very high	95	Very high	70 Å²	70	78.5 Å²	78.5	30%	0.304	40%	0.403	S	S	.	.	H	α-helix	trans	-57.7	-47.9	177.9	-73.3	178	177.5	-178.3	0	112.6	L8 N9 T15 K16 F138	L8-K12 WeakPolarHBondContact O-CG 3.47Å; L8-K12 PolarHBondContact O-N 3.01Å; N9-K12 PolarHBondContact O-N 3.05Å; K12-T15 PolarHBondContact O-N 2.98Å; K12-K16 WeakPolarHBondContact O-CG 3.49Å; K12-K16 PolarHBondContact O-N 3.18Å; K12-F138 HydrophobicContact CB-CD2 4.13Å; K12-F138 HydrophobicContact CB-CE2 4.28Å; K12-F138 HydrophobicContact CB-CG 4.4Å; K12-F138 HydrophobicContact CD-CD1 4.31Å; K12-F138 HydrophobicContact CD-CE1 4.35Å; K12-F138 HydrophobicContact CG-CD1 4.03Å; K12-F138 HydrophobicContact CG-CD2 4.03Å; K12-F138 HydrophobicContact CG-CE1 3.88Å; K12-F138 HydrophobicContact CG-CE2 3.87Å; K12-F138 HydrophobicContact CG-CG 4.11Å; K12-F138 HydrophobicContact CG-CZ 3.81Å
13	E	96.9	Very high	96.4	Very high	108 Å²	108	71.9 Å²	71.9	51%	0.505	37%	0.367	S	S	.	.	H	α-helix	trans	-66.6	-39.1	-179.5	-65.9	-52.8	118.6	0	0	111.6	N9 Y11 K16 V17	N9-E13 PolarHBondContact O-N 2.99Å; Y11-E13 PolarHBondContact O-N 3.43Å; E13-K16 PolarHBondContact O-N 3.31Å; E13-K16 IonicContact OE1-NZ 2.82Å; E13-K16 PolarHBondContact OE1-NZ 2.95Å; E13-K16 IonicContact OE2-NZ 3.94Å; E13-V17 PolarHBondContact O-N 3.42Å
14	K	97.6	Very high	96.7	Very high	129 Å²	129	70.3 Å²	70.3	56%	0.561	36%	0.355	S	S	*	.	H	α-helix	trans	-61	-47.3	171.8	-172.5	-172.8	175	-167.9	0	111.6	A10 Y11 K16 V17 D18	A10-K14 WeakPolarHBondContact O-CB 3.42Å; A10-K14 PolarHBondContact O-N 3.25Å; Y11-K14 PolarHBondContact O-N 2.96Å; K14-K16 PolarHBondContact O-N 2.95Å; K14-V17 PolarHBondContact O-N 3.34Å; K14-V17 VanDerWaalsContact O-N 3.09Å; K14-D18 VanDerWaalsContact CE-OD2 3.29Å; K14-D18 WeakPolarHBondContact CE-OD2 3.41Å; K14-D18 VanDerWaalsContact O-CG 3.31Å; K14-D18 PolarHBondContact O-N 2.76Å
15	T	97.8	Very high	96.8	Very high	4 Å²	4	67.6 Å²	67.6	3%	0.025	35%	0.345	C	S	.	.	H	α-helix	trans	-58	-34.6	177.6	-63.9	0	0	0	0	112.3	Y11 K12 G19 L131 L134 F138	Y11-T15 WeakPolarHBondContact O-CB 3.48Å; Y11-T15 PolarHBondContact O-N 2.98Å; Y11-T15 PolarHBondContact O-OG1 2.75Å; K12-T15 PolarHBondContact O-N 2.98Å; T15-G19 PolarHBondContact O-N 2.95Å; T15-L131 HydrophobicContact CG2-CD1 3.83Å; T15-L134 HydrophobicContact CG2-CB 3.97Å; T15-F138 HydrophobicContact CG2-CD2 3.75Å; T15-F138 HydrophobicContact CG2-CE2 3.71Å
16	K	96.8	Very high	97	Very high	49 Å²	49	64.8 Å²	64.8	21%	0.213	33%	0.328	C	S	.	.	H	α-helix	trans	-66.5	-41.7	175.6	-69.9	173.4	-178.7	167.7	0	113	K12 E13 K14 E20 W135 F138	K12-K16 WeakPolarHBondContact O-CG 3.49Å; K12-K16 PolarHBondContact O-N 3.18Å; E13-K16 PolarHBondContact O-N 3.31Å; E13-K16 IonicContact OE1-NZ 2.82Å; E13-K16 PolarHBondContact OE1-NZ 2.95Å; E13-K16 IonicContact OE2-NZ 3.94Å; K14-K16 PolarHBondContact O-N 2.95Å; K16-E20 WeakPolarHBondContact O-CB 3.44Å; K16-E20 PolarHBondContact O-N 2.73Å; K16-W135 PolarHBondContact O-NE1 2.92Å; K16-F138 VanDerWaalsContact CE-O 3.24Å; K16-F138 WeakPolarHBondContact CE-O 3.36Å; K16-F138 HydrophobicContact CG-CB 4.33Å
17	V	97.3	Very high	97.1	Very high	97 Å²	97	63.4 Å²	63.4	59%	0.588	31%	0.313	S	S	*	.	H	α-helix	trans	-65.7	-48.8	175.1	176.5	0	0	0	0	110.5	E13 K14 G19 E20 E21	E13-V17 PolarHBondContact O-N 3.42Å; K14-V17 PolarHBondContact O-N 3.34Å; K14-V17 VanDerWaalsContact O-N 3.09Å; V17-G19 VanDerWaalsContact C-N 3.33Å; V17-G19 PolarHBondContact O-N 3.42Å; V17-E20 PolarHBondContact O-N 3.37Å; V17-E21 WeakPolarHBondContact O-CB 3.29Å; V17-E21 PolarHBondContact O-N 3.25Å
18	D	97.8	Very high	97.2	Very high	63 Å²	63	58.6 Å²	58.6	34%	0.337	30%	0.301	S	S	.	.	H	α-helix	trans	-62.8	-40	-178.4	-65.9	-12.8	0	0	0	111.5	K14 L22 L131	K14-D18 VanDerWaalsContact CE-OD2 3.29Å; K14-D18 WeakPolarHBondContact CE-OD2 3.41Å; K14-D18 VanDerWaalsContact O-CG 3.31Å; K14-D18 PolarHBondContact O-N 2.76Å; D18-L22 WeakPolarHBondContact O-CB 3.48Å; D18-L22 PolarHBondContact O-N 2.87Å; D18-L131 HydrophobicContact CB-CD2 4.16Å
19	G	97.6	Very high	97.3	Very high	0 Å²	0	60.5 Å²	60.5	0%	0	31%	0.305	C	S	.	.	H	α-helix	trans	-66.9	-42.4	178.1	0	0	0	0	0	113.2	T15 V17 L22 V23	T15-G19 PolarHBondContact O-N 2.95Å; V17-G19 VanDerWaalsContact C-N 3.33Å; V17-G19 PolarHBondContact O-N 3.42Å; G19-L22 PolarHBondContact O-N 3.09Å; G19-V23 WeakPolarHBondContact O-CG1 3.45Å; G19-V23 WeakPolarHBondContact O-CG2 3.45Å; G19-V23 PolarHBondContact O-N 3.43Å
20	E	96.4	Very high	97.5	Very high	46 Å²	46	59 Å²	59	22%	0.215	29%	0.294	C	S	.	.	H	α-helix	trans	-67.3	-43.9	175.8	-171.9	168.3	180	0	0	111.4	K16 V17 L22 V23 L24 W135 K239	K16-E20 WeakPolarHBondContact O-CB 3.44Å; K16-E20 PolarHBondContact O-N 2.73Å; V17-E20 PolarHBondContact O-N 3.37Å; E20-L22 VanDerWaalsContact C-N 3.33Å; E20-L22 PolarHBondContact O-N 3.24Å; E20-V23 VanDerWaalsContact O-CG2 3.24Å; E20-V23 WeakPolarHBondContact O-CG2 3.23Å; E20-V23 PolarHBondContact O-N 3.3Å; E20-L24 HydrophobicContact CG-CD1 3.8Å; E20-L24 HydrophobicContact CG-CG 4.25Å; E20-L24 WeakPolarHBondContact O-CB 3.37Å; E20-L24 WeakPolarHBondContact O-CG 3.28Å; E20-L24 PolarHBondContact O-N 2.88Å; E20-W135 HydrophobicContact CB-CZ2 3.97Å; E20-W135 HydrophobicContact CG-CZ2 4.32Å; E20-K239 IonicContact OE1-NZ 3.81Å; E20-K239 PolarHBondContact OE1-NZ 2.82Å; E20-K239 WeakPolarHBondContact OE2-CE 3.49Å; E20-K239 IonicContact OE2-NZ 2.8Å; E20-K239 PolarHBondContact OE2-NZ 3.48Å
21	E	97.5	Very high	97.6	Very high	97 Å²	97	57.2 Å²	57.2	45%	0.453	28%	0.276	S	S	.	.	H	α-helix	trans	-59.8	-43.1	175.1	175.6	60.2	-160.3	0	0	112.1	V17 V23 L24 N25	V17-E21 WeakPolarHBondContact O-CB 3.29Å; V17-E21 PolarHBondContact O-N 3.25Å; E21-V23 PolarHBondContact O-N 3.03Å; E21-L24 PolarHBondContact O-N 2.83Å; E21-N25 WeakPolarHBondContact O-CB 3.24Å; E21-N25 PolarHBondContact O-N 2.95Å; E21-N25 VanDerWaalsContact OE1-CB 3.28Å; E21-N25 WeakPolarHBondContact OE1-CB 3.5Å; E21-N25 PolarHBondContact OE1-ND2 3.44Å; E21-N25 PolarHBondContact OE2-ND2 3.03Å
22	L	97.8	Very high	97.6	Very high	13 Å²	13	57.6 Å²	57.6	7%	0.068	28%	0.28	C	S	.	.	I	π-helix	trans	-57.6	-51.3	179.3	178.3	75.2	0	0	0	111.1	D18 G19 E20 V26 F27 E128 L131 V132	D18-L22 WeakPolarHBondContact O-CB 3.48Å; D18-L22 PolarHBondContact O-N 2.87Å; G19-L22 PolarHBondContact O-N 3.09Å; E20-L22 VanDerWaalsContact C-N 3.33Å; E20-L22 PolarHBondContact O-N 3.24Å; L22-V26 HydrophobicContact CD1-CB 3.83Å; L22-V26 HydrophobicContact CD1-CG1 3.88Å; L22-V26 HydrophobicContact CD1-CG2 4.21Å; L22-V26 WeakPolarHBondContact O-CA 3.26Å; L22-V26 VanDerWaalsContact O-CB 3.27Å; L22-V26 WeakPolarHBondContact O-CB 3.14Å; L22-V26 PolarHBondContact O-N 2.86Å; L22-F27 HydrophobicContact CD1-CD1 4.28Å; L22-F27 HydrophobicContact CD1-CE1 3.94Å; L22-F27 HydrophobicContact CD2-CE1 3.67Å; L22-F27 HydrophobicContact CD2-CZ 3.97Å; L22-F27 HydrophobicContact CG-CD1 3.99Å; L22-F27 HydrophobicContact CG-CE1 3.49Å; L22-F27 VanDerWaalsContact CG-CE1 3.49Å; L22-F27 HydrophobicContact CG-CZ 4.15Å; L22-F27 PolarHBondContact O-N 3.29Å; L22-E128 HydrophobicContact CD1-CB 4.18Å; L22-E128 HydrophobicContact CD1-CG 3.69Å; L22-E128 HydrophobicContact CD2-CB 3.87Å; L22-E128 HydrophobicContact CD2-CG 4.21Å; L22-E128 WeakPolarHBondContact CD2-O 3.4Å; L22-L131 HydrophobicContact CD2-CB 4.24Å; L22-L131 HydrophobicContact CD2-CD2 4.05Å; L22-L131 HydrophobicContact CD2-CG 4.29Å; L22-V132 HydrophobicContact CD2-CG2 3.84Å
23	V	96.9	Very high	97.7	Very high	0 Å²	0	58 Å²	58	0%	0	28%	0.283	C	S	.	.	I	π-helix	trans	-71.6	-37.2	-176.9	-59.4	0	0	0	0	111.8	G19 E20 E21 F27 V132 W135 H228 I231	G19-V23 WeakPolarHBondContact O-CG1 3.45Å; G19-V23 WeakPolarHBondContact O-CG2 3.45Å; G19-V23 PolarHBondContact O-N 3.43Å; E20-V23 VanDerWaalsContact O-CG2 3.24Å; E20-V23 WeakPolarHBondContact O-CG2 3.23Å; E20-V23 PolarHBondContact O-N 3.3Å; E21-V23 PolarHBondContact O-N 3.03Å; V23-F27 HydrophobicContact CB-CD2 4.3Å; V23-F27 HydrophobicContact CB-CE2 4.43Å; V23-F27 HydrophobicContact CG1-CD2 4.11Å; V23-F27 HydrophobicContact CG1-CE2 3.75Å; V23-F27 HydrophobicContact CG1-CZ 4.2Å; V23-V132 HydrophobicContact CG1-CG2 3.62Å; V23-W135 HydrophobicContact CB-CZ3 4.48Å; V23-W135 HydrophobicContact CG1-CE3 4.42Å; V23-W135 HydrophobicContact CG1-CZ3 3.92Å; V23-W135 HydrophobicContact CG2-CH2 3.83Å; V23-W135 HydrophobicContact CG2-CZ3 3.78Å; V23-H228 PolarHBondContact O-CD2 3.27Å; V23-I231 HydrophobicContact CB-CD1 4.46Å; V23-I231 HydrophobicContact CB-CG2 4.11Å; V23-I231 HydrophobicContact CG1-CD1 3.73Å; V23-I231 HydrophobicContact CG1-CG2 4.34Å; V23-I231 HydrophobicContact CG2-CG2 3.84Å
24	L	97	Very high	97.8	Very high	58 Å²	58	53.1 Å²	53.1	30%	0.304	26%	0.26	S	S	.	.	I	π-helix	trans	-75.1	-40.6	-177.4	-66.3	-176.7	0	0	0	112.6	E20 E21 I232 L235	E20-L24 HydrophobicContact CG-CD1 3.8Å; E20-L24 HydrophobicContact CG-CG 4.25Å; E20-L24 WeakPolarHBondContact O-CB 3.37Å; E20-L24 WeakPolarHBondContact O-CG 3.28Å; E20-L24 PolarHBondContact O-N 2.88Å; E21-L24 PolarHBondContact O-N 2.83Å; L24-I232 HydrophobicContact CD2-CD1 3.25Å; L24-L235 HydrophobicContact CD2-CD2 4.26Å
25	N	97.3	Very high	97.8	Very high	71 Å²	71	51.5 Å²	51.5	38%	0.38	26%	0.255	S	S	.	.	I	π-helix	trans	-120.6	-21.8	-163.9	-68.4	-46.9	0	0	0	114.5	E21 K29	E21-N25 WeakPolarHBondContact O-CB 3.24Å; E21-N25 PolarHBondContact O-N 2.95Å; E21-N25 VanDerWaalsContact OE1-CB 3.28Å; E21-N25 WeakPolarHBondContact OE1-CB 3.5Å; E21-N25 PolarHBondContact OE1-ND2 3.44Å; E21-N25 PolarHBondContact OE2-ND2 3.03Å; N25-K29 VanDerWaalsContact O-CD 3.26Å; N25-K29 WeakPolarHBondContact O-CD 3.27Å; N25-K29 WeakPolarHBondContact O-CE 3.21Å; N25-K29 PolarHBondContact O-NZ 3.46Å
26	V	98.2	Very high	97.8	Very high	36 Å²	36	56.9 Å²	56.9	22%	0.218	28%	0.283	C	S	.	.	I	π-helix	trans	-98.1	-46	-177.9	-177.7	0	0	0	0	111	L22 K29 R30	L22-V26 HydrophobicContact CD1-CB 3.83Å; L22-V26 HydrophobicContact CD1-CG1 3.88Å; L22-V26 HydrophobicContact CD1-CG2 4.21Å; L22-V26 WeakPolarHBondContact O-CA 3.26Å; L22-V26 VanDerWaalsContact O-CB 3.27Å; L22-V26 WeakPolarHBondContact O-CB 3.14Å; L22-V26 PolarHBondContact O-N 2.86Å; V26-K29 WeakPolarHBondContact O-CA 3.4Å; V26-K29 WeakPolarHBondContact O-CB 3.22Å; V26-K29 PolarHBondContact O-N 2.88Å; V26-R30 HydrophobicContact CG1-CG 4.08Å; V26-R30 WeakPolarHBondContact O-CG 3.42Å; V26-R30 PolarHBondContact O-N 3.01Å
27	F	98.4	Very high	97.8	Very high	1 Å²	1	55.3 Å²	55.3	0%	0.004	28%	0.277	C	S	.	.	H	α-helix	trans	-55.4	-44.6	-177.9	-76.2	8.1	0	0	0	114.1	L22 V23 K29 R30 V31 E128 V132 Y224 L227 H228	L22-F27 HydrophobicContact CD1-CD1 4.28Å; L22-F27 HydrophobicContact CD1-CE1 3.94Å; L22-F27 HydrophobicContact CD2-CE1 3.67Å; L22-F27 HydrophobicContact CD2-CZ 3.97Å; L22-F27 HydrophobicContact CG-CD1 3.99Å; L22-F27 HydrophobicContact CG-CE1 3.49Å; L22-F27 VanDerWaalsContact CG-CE1 3.49Å; L22-F27 HydrophobicContact CG-CZ 4.15Å; L22-F27 PolarHBondContact O-N 3.29Å; V23-F27 HydrophobicContact CB-CD2 4.3Å; V23-F27 HydrophobicContact CB-CE2 4.43Å; V23-F27 HydrophobicContact CG1-CD2 4.11Å; V23-F27 HydrophobicContact CG1-CE2 3.75Å; V23-F27 HydrophobicContact CG1-CZ 4.2Å; F27-K29 VanDerWaalsContact C-N 3.26Å; F27-K29 PolarHBondContact O-N 3.18Å; F27-R30 WeakPolarHBondContact O-CB 3.28Å; F27-R30 PolarHBondContact O-N 2.93Å; F27-R30 VanDerWaalsContact O-N 3.13Å; F27-V31 WeakPolarHBondContact O-CG2 3.44Å; F27-V31 PolarHBondContact O-N 2.71Å; F27-V31 VanDerWaalsContact O-N 3.08Å; F27-E128 HydrophobicContact CE1-CB 4.13Å; F27-V132 HydrophobicContact CE2-CG2 4.05Å; F27-V132 HydrophobicContact CZ-CG2 3.63Å; F27-Y224 HydrophobicContact CB-CD1 4.39Å; F27-Y224 AromaticContact CD1-CD1 3.56Å; F27-Y224 HydrophobicContact CD1-CD1 3.56Å; F27-Y224 AromaticContact CD1-CE1 3.74Å; F27-Y224 HydrophobicContact CD1-CE1 3.74Å; F27-Y224 HydrophobicContact CD2-CD1 4.34Å; F27-Y224 AromaticContact CE1-CD1 3.77Å; F27-Y224 HydrophobicContact CE1-CD1 3.77Å; F27-Y224 AromaticContact CE1-CE1 3.65Å; F27-Y224 HydrophobicContact CE1-CE1 3.65Å; F27-Y224 AromaticContact CG-CD1 3.85Å; F27-Y224 HydrophobicContact CG-CD1 3.85Å; F27-Y224 HydrophobicContact CG-CE1 4.49Å; F27-Y224 HydrophobicContact CZ-CD1 4.26Å; F27-Y224 HydrophobicContact CZ-CE1 4.36Å; F27-L227 HydrophobicContact CE2-CB 4.21Å; F27-L227 HydrophobicContact CE2-CD2 3.57Å; F27-L227 HydrophobicContact CE2-CG 3.85Å; F27-L227 HydrophobicContact CZ-CD2 3.95Å; F27-H228 HydrophobicContact CB-CB 4.08Å; F27-H228 HydrophobicContact CD2-CB 4.15Å
28	P	98.4	Very high	97.7	Very high	41 Å²	41	51.6 Å²	51.6	27%	0.266	25%	0.254	S	S	.	.	H	α-helix	trans	-58.6	-38.8	175.3	-26.1	36.9	0	0	0	112.7	V31 F32 H228	P28-V31 PolarHBondContact O-N 3.42Å; P28-F32 WeakPolarHBondContact O-CD2 3.37Å; P28-F32 PolarHBondContact O-N 2.81Å; P28-H228 WeakPolarHBondContact CG-NE2 3.39Å
29	K	98.4	Very high	97.6	Very high	125 Å²	125	52.5 Å²	52.5	54%	0.543	27%	0.27	S	S	.	.	H	α-helix	trans	-65.8	-42.3	177.1	-61.1	173.4	-175	160	0	111	N25 V26 F27 V31 F32 E33	N25-K29 VanDerWaalsContact O-CD 3.26Å; N25-K29 WeakPolarHBondContact O-CD 3.27Å; N25-K29 WeakPolarHBondContact O-CE 3.21Å; N25-K29 PolarHBondContact O-NZ 3.46Å; V26-K29 WeakPolarHBondContact O-CA 3.4Å; V26-K29 WeakPolarHBondContact O-CB 3.22Å; V26-K29 PolarHBondContact O-N 2.88Å; F27-K29 VanDerWaalsContact C-N 3.26Å; F27-K29 PolarHBondContact O-N 3.18Å; K29-V31 VanDerWaalsContact C-N 3.29Å; K29-V31 PolarHBondContact O-N 3.36Å; K29-F32 PolarHBondContact O-N 3.02Å; K29-E33 WeakPolarHBondContact O-CG 3.39Å; K29-E33 PolarHBondContact O-N 2.93Å
30	R	98.3	Very high	97.4	Very high	52 Å²	52	54.6 Å²	54.6	20%	0.196	29%	0.285	C	S	.	.	H	α-helix	trans	-58.5	-40	176.5	-63.9	-57.9	-168.5	-162.5	-2.6	112.6	V26 F27 F32 E33 M34 E128 Y224	V26-R30 HydrophobicContact CG1-CG 4.08Å; V26-R30 WeakPolarHBondContact O-CG 3.42Å; V26-R30 PolarHBondContact O-N 3.01Å; F27-R30 WeakPolarHBondContact O-CB 3.28Å; F27-R30 PolarHBondContact O-N 2.93Å; F27-R30 VanDerWaalsContact O-N 3.13Å; R30-F32 VanDerWaalsContact C-N 3.33Å; R30-F32 PolarHBondContact O-N 3.22Å; R30-E33 VanDerWaalsContact CD-OE2 3.23Å; R30-E33 WeakPolarHBondContact CD-OE2 3.49Å; R30-E33 IonicContact CZ-OE2 2.88Å; R30-E33 IonicContact NE-OE2 3.59Å; R30-E33 IonicContact NH1-OE1 3.93Å; R30-E33 IonicContact NH1-OE2 3.51Å; R30-E33 PolarHBondContact NH1-OE2 3.21Å; R30-E33 PolarHBondContact O-N 3.17Å; R30-M34 WeakPolarHBondContact O-CG 3.24Å; R30-M34 PolarHBondContact O-N 3.44Å; R30-E128 IonicContact CZ-OE1 3.18Å; R30-E128 IonicContact NE-OE1 3.59Å; R30-E128 PolarHBondContact NE-OE1 3.23Å; R30-E128 IonicContact NE-OE2 2.58Å; R30-E128 IonicContact NH2-OE1 3.87Å; R30-E128 PolarHBondContact NH2-OE1 3.48Å; R30-Y224 HydrophobicContact CB-CD1 4Å; R30-Y224 HydrophobicContact CB-CD2 3.49Å; R30-Y224 VanDerWaalsContact CB-CD2 3.49Å; R30-Y224 HydrophobicContact CB-CE1 4.08Å; R30-Y224 HydrophobicContact CB-CE2 3.58Å; R30-Y224 HydrophobicContact CB-CG 3.7Å; R30-Y224 HydrophobicContact CG-CD1 4.22Å; R30-Y224 HydrophobicContact CG-CD2 4.27Å; R30-Y224 HydrophobicContact CG-CE1 3.88Å; R30-Y224 HydrophobicContact CG-CE2 3.93Å; R30-Y224 HydrophobicContact CG-CG 4.4Å
31	V	98.6	Very high	97.2	Very high	25 Å²	25	59.5 Å²	59.5	15%	0.152	31%	0.312	C	S	.	.	H	α-helix	trans	-56.3	-49.9	176.6	172.7	0	0	0	0	110.5	F27 P28 K29 M34 E35 R221 A225	F27-V31 WeakPolarHBondContact O-CG2 3.44Å; F27-V31 PolarHBondContact O-N 2.71Å; F27-V31 VanDerWaalsContact O-N 3.08Å; P28-V31 PolarHBondContact O-N 3.42Å; K29-V31 VanDerWaalsContact C-N 3.29Å; K29-V31 PolarHBondContact O-N 3.36Å; V31-M34 PolarHBondContact O-N 2.93Å; V31-E35 PolarHBondContact O-N 3.4Å; V31-E35 VanDerWaalsContact O-N 3.09Å; V31-R221 HydrophobicContact CG1-CG 3.9Å; V31-A225 HydrophobicContact CG2-CB 3.93Å
32	F	98.4	Very high	97	Very high	125 Å²	125	58.1 Å²	58.1	55%	0.548	31%	0.306	S	S	.	.	H	α-helix	trans	-72.7	-33.7	180	-62.8	-62.4	0	0	0	113	P28 K29 R30 M34 E35 D36	P28-F32 WeakPolarHBondContact O-CD2 3.37Å; P28-F32 PolarHBondContact O-N 2.81Å; K29-F32 PolarHBondContact O-N 3.02Å; R30-F32 VanDerWaalsContact C-N 3.33Å; R30-F32 PolarHBondContact O-N 3.22Å; F32-M34 VanDerWaalsContact C-N 3.26Å; F32-M34 PolarHBondContact O-N 3.41Å; F32-E35 WeakPolarHBondContact CD1-OE2 3.35Å; F32-E35 WeakPolarHBondContact O-CB 3.48Å; F32-E35 PolarHBondContact O-N 3.5Å; F32-E35 VanDerWaalsContact O-N 3.12Å; F32-D36 PolarHBondContact O-N 2.95Å
33	E	98.2	Very high	96.7	Very high	77 Å²	77	57.5 Å²	57.5	36%	0.36	30%	0.303	S	S	.	.	H	α-helix	trans	-57.7	-40.2	170.7	-73.6	172.1	-169.2	0	0	111.6	K29 R30 I37	K29-E33 WeakPolarHBondContact O-CG 3.39Å; K29-E33 PolarHBondContact O-N 2.93Å; R30-E33 VanDerWaalsContact CD-OE2 3.23Å; R30-E33 WeakPolarHBondContact CD-OE2 3.49Å; R30-E33 IonicContact CZ-OE2 2.88Å; R30-E33 IonicContact NE-OE2 3.59Å; R30-E33 IonicContact NH1-OE1 3.93Å; R30-E33 IonicContact NH1-OE2 3.51Å; R30-E33 PolarHBondContact NH1-OE2 3.21Å; R30-E33 PolarHBondContact O-N 3.17Å; E33-I37 VanDerWaalsContact O-CG1 3.26Å; E33-I37 WeakPolarHBondContact O-CG1 3.2Å; E33-I37 PolarHBondContact O-N 3.1Å; E33-I37 VanDerWaalsContact O-N 3.17Å
34	M	98.5	Very high	96.2	Very high	6 Å²	6	63.5 Å²	63.5	3%	0.03	33%	0.33	C	S	.	.	H	α-helix	trans	-72.1	-33.9	176.5	-63.8	-50.6	102.8	0	0	112.1	R30 V31 F32 I37 L38 C121 I217 I220 R221	R30-M34 WeakPolarHBondContact O-CG 3.24Å; R30-M34 PolarHBondContact O-N 3.44Å; V31-M34 PolarHBondContact O-N 2.93Å; F32-M34 VanDerWaalsContact C-N 3.26Å; F32-M34 PolarHBondContact O-N 3.41Å; M34-I37 HydrophobicContact CE-CD1 3.83Å; M34-I37 PolarHBondContact O-N 3.31Å; M34-I37 HydrophobicContact SD-CD1 4.14Å; M34-L38 VanDerWaalsContact O-CG 3.28Å; M34-L38 WeakPolarHBondContact O-CG 3.45Å; M34-L38 PolarHBondContact O-N 3Å; M34-C121 HydrophobicContact CE-CB 4.16Å; M34-C121 HydrophobicContact SD-CB 4.04Å; M34-I217 HydrophobicContact CB-CG2 4.06Å; M34-I217 HydrophobicContact SD-CG2 4.11Å; M34-I220 HydrophobicContact CG-CB 4.33Å; M34-I220 HydrophobicContact CG-CG2 3.81Å; M34-I220 HydrophobicContact SD-CB 4.2Å; M34-I220 HydrophobicContact SD-CG2 3.63Å; M34-R221 HydrophobicContact CB-CB 3.63Å; M34-R221 HydrophobicContact CB-CG 4.09Å; M34-R221 HydrophobicContact CG-CB 4.12Å
35	E	97.6	Very high	95.2	Very high	96 Å²	96	64.4 Å²	64.4	45%	0.449	33%	0.334	S	S	.	.	H	α-helix	trans	-62.9	-44.9	173.7	-172.5	168.5	-166.9	0	0	111.5	V31 F32 I37 L38 A39	V31-E35 PolarHBondContact O-N 3.4Å; V31-E35 VanDerWaalsContact O-N 3.09Å; F32-E35 WeakPolarHBondContact CD1-OE2 3.35Å; F32-E35 WeakPolarHBondContact O-CB 3.48Å; F32-E35 PolarHBondContact O-N 3.5Å; F32-E35 VanDerWaalsContact O-N 3.12Å; E35-I37 VanDerWaalsContact C-N 3.31Å; E35-I37 PolarHBondContact O-N 3.44Å; E35-L38 PolarHBondContact O-N 2.91Å; E35-L38 VanDerWaalsContact O-N 3.15Å; E35-A39 WeakPolarHBondContact O-CB 3.47Å; E35-A39 PolarHBondContact O-N 3.31Å
36	D	97.6	Very high	94	Very high	117 Å²	117	65.4 Å²	65.4	63%	0.626	34%	0.337	S	S	*	.	H	α-helix	trans	-60.5	-40	175.2	-70.4	-22.1	0	0	0	111.9	F32 A39 S40	F32-D36 PolarHBondContact O-N 2.95Å; D36-A39 PolarHBondContact O-N 2.82Å; D36-S40 PolarHBondContact O-N 3.4Å
37	I	97.1	Very high	92.3	Very high	15 Å²	15	65.4 Å²	65.4	8%	0.077	34%	0.344	C	S	.	.	H	α-helix	trans	-63.8	-45.1	175	-67.8	168.7	0	0	0	110.7	E33 M34 E35 A39 S40 F43 K117 I217	E33-I37 VanDerWaalsContact O-CG1 3.26Å; E33-I37 WeakPolarHBondContact O-CG1 3.2Å; E33-I37 PolarHBondContact O-N 3.1Å; E33-I37 VanDerWaalsContact O-N 3.17Å; M34-I37 HydrophobicContact CE-CD1 3.83Å; M34-I37 PolarHBondContact O-N 3.31Å; M34-I37 HydrophobicContact SD-CD1 4.14Å; E35-I37 VanDerWaalsContact C-N 3.31Å; E35-I37 PolarHBondContact O-N 3.44Å; I37-A39 VanDerWaalsContact C-N 3.27Å; I37-A39 PolarHBondContact O-N 3.08Å; I37-S40 WeakPolarHBondContact O-CB 3.43Å; I37-S40 PolarHBondContact O-N 3.42Å; I37-S40 PolarHBondContact O-OG 2.92Å; I37-F43 HydrophobicContact CG2-CD2 3.62Å; I37-F43 HydrophobicContact CG2-CE2 3.4Å; I37-F43 HydrophobicContact CG2-CG 4.41Å; I37-F43 HydrophobicContact CG2-CZ 4.02Å; I37-F43 WeakPolarHBondContact O-CD2 3.33Å; I37-K117 HydrophobicContact CG2-CG 4.23Å; I37-I217 HydrophobicContact CB-CG2 4.3Å; I37-I217 HydrophobicContact CG2-CD1 4.26Å; I37-I217 HydrophobicContact CG2-CG1 4.22Å; I37-I217 HydrophobicContact CG2-CG2 4.05Å
38	L	96.4	Very high	90.7	Very high	20 Å²	20	74.1 Å²	74.1	11%	0.105	38%	0.382	C	S	.	.	H	α-helix	trans	-66	-29.1	179.2	-73.3	166.9	0	0	0	113	M34 E35 S40 R214 I217 M218	M34-L38 VanDerWaalsContact O-CG 3.28Å; M34-L38 WeakPolarHBondContact O-CG 3.45Å; M34-L38 PolarHBondContact O-N 3Å; E35-L38 PolarHBondContact O-N 2.91Å; E35-L38 VanDerWaalsContact O-N 3.15Å; L38-S40 VanDerWaalsContact C-N 3.33Å; L38-R214 HydrophobicContact CD2-CG 3.74Å; L38-I217 HydrophobicContact CD1-CG2 4.12Å; L38-I217 HydrophobicContact CD2-CB 3.93Å; L38-I217 HydrophobicContact CD2-CG2 3.84Å; L38-I217 HydrophobicContact CG-CB 4.27Å; L38-I217 HydrophobicContact CG-CG2 3.6Å; L38-M218 HydrophobicContact CD1-CG 3.8Å; L38-M218 HydrophobicContact CD2-CG 3.8Å; L38-M218 HydrophobicContact CG-CG 4.49Å
39	A	95	Very high	89.3	Confident	81 Å²	81	79.5 Å²	79.5	67%	0.669	40%	0.398	S	S	*	.	H	α-helix	trans	-79.6	-13.8	176.4	0	0	0	0	0	113.4	E35 D36 I37	E35-A39 WeakPolarHBondContact O-CB 3.47Å; E35-A39 PolarHBondContact O-N 3.31Å; D36-A39 PolarHBondContact O-N 2.82Å; I37-A39 VanDerWaalsContact C-N 3.27Å; I37-A39 PolarHBondContact O-N 3.08Å
40	S	94.3	Very high	88.4	Confident	45 Å²	45	73.7 Å²	73.7	32%	0.315	37%	0.373	S	S	.	.	S	Bend	trans	-72	149.2	178.8	75.4	0	0	0	0	112.9	D36 I37 L38 M42 F43 F44	D36-S40 PolarHBondContact O-N 3.4Å; I37-S40 WeakPolarHBondContact O-CB 3.43Å; I37-S40 PolarHBondContact O-N 3.42Å; I37-S40 PolarHBondContact O-OG 2.92Å; L38-S40 VanDerWaalsContact C-N 3.33Å; S40-M42 PolarHBondContact O-N 3.31Å; S40-F43 PolarHBondContact O-N 3Å; S40-F44 PolarHBondContact O-N 2.91Å
41	D	91.8	Very high	87.6	Confident	149 Å²	149	73.9 Å²	73.9	80%	0.797	38%	0.376	S	S	*	.	G	3₁₀ helix	trans	-54.1	-27.7	177.1	-63.2	-20.3	0	0	0	113.3	F43 F44	D41-F43 VanDerWaalsContact C-N 3.25Å; D41-F43 PolarHBondContact O-N 3.31Å; D41-F44 WeakPolarHBondContact O-CB 3.31Å; D41-F44 PolarHBondContact O-N 3.38Å
42	M	91.8	Very high	86.8	Confident	67 Å²	67	74 Å²	74	33%	0.33	38%	0.378	S	S	.	.	G	3₁₀ helix	trans	-61.4	-32.9	178.1	-178.5	-177.2	-63.4	0	0	112.8	S40 H110 A113 M114 K117	S40-M42 PolarHBondContact O-N 3.31Å; M42-H110 PolarHBondContact O-CE1 3.45Å; M42-H110 VanDerWaalsContact O-CE1 3.27Å; M42-H110 PolarHBondContact O-NE2 3.37Å; M42-A113 HydrophobicContact CE-CB 4.16Å; M42-A113 HydrophobicContact SD-CB 4.48Å; M42-M114 HydrophobicContact CG-CG 3.96Å; M42-K117 HydrophobicContact SD-CB 4Å; M42-K117 HydrophobicContact SD-CG 4.4Å
43	F	92.8	Very high	85.8	Confident	1 Å²	1	74.4 Å²	74.4	0%	0.004	39%	0.386	C	S	.	.	G	3₁₀ helix	trans	-104.8	9.5	-178.8	-73.2	-91	0	0	0	112.6	I37 S40 D41 M114 K117 M213 R214 I217	I37-F43 HydrophobicContact CG2-CD2 3.62Å; I37-F43 HydrophobicContact CG2-CE2 3.4Å; I37-F43 HydrophobicContact CG2-CG 4.41Å; I37-F43 HydrophobicContact CG2-CZ 4.02Å; I37-F43 WeakPolarHBondContact O-CD2 3.33Å; S40-F43 PolarHBondContact O-N 3Å; D41-F43 VanDerWaalsContact C-N 3.25Å; D41-F43 PolarHBondContact O-N 3.31Å; F43-M114 HydrophobicContact CD1-CE 3.46Å; F43-M114 VanDerWaalsContact CD1-CE 3.46Å; F43-M114 HydrophobicContact CE1-CB 4.4Å; F43-M114 HydrophobicContact CE1-CE 3.69Å; F43-M114 HydrophobicContact CG-CE 4.16Å; F43-M114 HydrophobicContact CZ-CB 4.28Å; F43-K117 HydrophobicContact CE2-CB 4.3Å; F43-K117 HydrophobicContact CE2-CG 4.05Å; F43-K117 HydrophobicContact CZ-CB 4.41Å; F43-K117 HydrophobicContact CZ-CG 4.44Å; F43-M213 HydrophobicContact CE1-CB 4.19Å; F43-R214 HydrophobicContact CB-CG 4.49Å; F43-R214 HydrophobicContact CD1-CB 4.08Å; F43-R214 HydrophobicContact CD1-CG 4.37Å; F43-R214 WeakPolarHBondContact O-CD 3.43Å; F43-R214 PolarHBondContact O-NE 3.26Å; F43-I217 HydrophobicContact CD1-CG1 4.32Å; F43-I217 HydrophobicContact CE1-CG1 3.65Å; F43-I217 HydrophobicContact CZ-CD1 4.36Å; F43-I217 HydrophobicContact CZ-CG1 3.86Å
44	F	85.2	Confident	85	Confident	126 Å²	126	71.8 Å²	71.8	55%	0.553	38%	0.375	S	S	*	.			trans	-80.1	116.1	171.6	-165.2	-107.3	0	0	0	110.2	S40 D41 E46	S40-F44 PolarHBondContact O-N 2.91Å; D41-F44 WeakPolarHBondContact O-CB 3.31Å; D41-F44 PolarHBondContact O-N 3.38Å; F44-E46 VanDerWaalsContact C-N 3.34Å; F44-E46 HydrophobicContact CD1-CB 4.39Å; F44-E46 HydrophobicContact CD1-CG 3.96Å; F44-E46 HydrophobicContact CE1-CG 3.61Å; F44-E46 WeakPolarHBondContact CE1-OE1 3.36Å; F44-E46 PolarHBondContact O-N 2.95Å
45	L	76.9	Confident	84.2	Confident	77 Å²	77	76.5 Å²	76.5	40%	0.403	40%	0.4	S	S	.	.			trans	-85.1	70.2	-171.5	-63.1	173.7	0	0	0	111.9	A210 I211	L45-A210 HydrophobicContact CD2-CB 3.88Å; L45-I211 HydrophobicContact CD1-CG1 4.07Å; L45-I211 HydrophobicContact CD2-CG1 4.49Å
46	E	72.2	Confident	83.4	Confident	91 Å²	91	72.1 Å²	72.1	43%	0.425	38%	0.38	S	S	.	.			trans	-95.8	119.2	162.8	-88.3	-172.8	-167.5	0	0	110.1	F44 K48 Y49	F44-E46 VanDerWaalsContact C-N 3.34Å; F44-E46 HydrophobicContact CD1-CB 4.39Å; F44-E46 HydrophobicContact CD1-CG 3.96Å; F44-E46 HydrophobicContact CE1-CG 3.61Å; F44-E46 WeakPolarHBondContact CE1-OE1 3.36Å; F44-E46 PolarHBondContact O-N 2.95Å; E46-K48 PolarHBondContact O-N 3.26Å; E46-Y49 HydrophobicContact CB-CD2 3.74Å; E46-Y49 HydrophobicContact CB-CE2 3.94Å; E46-Y49 PolarHBondContact O-N 2.84Å; E46-Y49 VanDerWaalsContact O-N 3.09Å; E46-Y49 WeakPolarHBondContact OE2-CE2 3.37Å
47	G	61.5	Low	82.5	Confident	36 Å²	36	68.6 Å²	68.6	37%	0.371	36%	0.364	S	S	.	.	H	α-helix	trans	-55.8	-26.1	-170.1	0	0	0	0	0	115.2	Y49 V50 H51	G47-Y49 VanDerWaalsContact C-N 3.28Å; G47-Y49 PolarHBondContact O-N 3.38Å; G47-V50 PolarHBondContact O-N 3.44Å; G47-H51 PolarHBondContact O-CE1 3.43Å; G47-H51 PolarHBondContact O-NE2 3.5Å
48	K	65.8	Low	81.5	Confident	185 Å²	185	73.5 Å²	73.5	80%	0.804	38%	0.382	S	S	*	.	H	α-helix	trans	-65.1	-28.3	-179.8	-64.4	-177.1	-177.9	177	0	113.7	E46	E46-K48 PolarHBondContact O-N 3.26Å
49	Y	68.5	Low	80.3	Confident	153 Å²	153	74.8 Å²	74.8	60%	0.6	39%	0.392	S	S	*	.	H	α-helix	trans	-88.5	-12.4	-177.6	-59	-71.3	0	0	0	113.3	E46 G47	E46-Y49 HydrophobicContact CB-CD2 3.74Å; E46-Y49 HydrophobicContact CB-CE2 3.94Å; E46-Y49 PolarHBondContact O-N 2.84Å; E46-Y49 VanDerWaalsContact O-N 3.09Å; E46-Y49 WeakPolarHBondContact OE2-CE2 3.37Å; G47-Y49 VanDerWaalsContact C-N 3.28Å; G47-Y49 PolarHBondContact O-N 3.38Å
50	V	79.3	Confident	78.9	Confident	4 Å²	4	76.5 Å²	76.5	2%	0.024	39%	0.394	C	S	.	.	H	α-helix	trans	-91.8	-16.8	-174.1	-174	0	0	0	0	111.9	G47 N108 I111 D206 A210	G47-V50 PolarHBondContact O-N 3.44Å; V50-N108 PolarHBondContact O-ND2 2.87Å; V50-I111 HydrophobicContact CG1-CD1 3.88Å; V50-I111 HydrophobicContact CG1-CG1 4.48Å; V50-D206 HydrophobicContact CG1-CB 4.48Å; V50-D206 WeakPolarHBondContact CG1-O 3.48Å; V50-A210 HydrophobicContact CB-CB 4.45Å; V50-A210 HydrophobicContact CG1-CB 3.59Å; V50-A210 HydrophobicContact CG2-CB 3.91Å
51	H	82.4	Confident	77.3	Confident	56 Å²	56	80 Å²	80	26%	0.259	41%	0.409	S	S	.	.			trans	-82.5	145.8	-176.6	-59.2	162	0	0	0	112.3	G47 R203 E207	G47-H51 PolarHBondContact O-CE1 3.43Å; G47-H51 PolarHBondContact O-NE2 3.5Å; H51-R203 PolarHBondContact CE1-NH2 3.37Å; H51-R203 PolarHBondContact ND1-NH2 3.2Å; H51-E207 IonicContact CD2-OE1 3.18Å; H51-E207 IonicContact CE1-OE1 3.56Å; H51-E207 PolarHBondContact CE1-OE1 3.13Å; H51-E207 VanDerWaalsContact CE1-OE1 3.3Å; H51-E207 IonicContact NE2-OE1 2.78Å; H51-E207 PolarHBondContact NE2-OE1 2.99Å
52	S	81.8	Confident	75.7	Confident	28 Å²	28	77.8 Å²	77.8	20%	0.196	40%	0.403	C	S	.	.			trans	-130.3	126.9	172.9	172.5	0	0	0	0	108.9	V54 N108	S52-V54 PolarHBondContact O-N 3.3Å; S52-N108 WeakPolarHBondContact CB-ND2 3.44Å
53	D	77.5	Confident	74	Confident	132 Å²	132	82.3 Å²	82.3	71%	0.706	42%	0.423	S	S	*	.			trans	-63.8	131.9	-179.8	-65.1	-33.5	0	0	0	111.8
54	V	81.6	Confident	71.9	Confident	22 Å²	22	89 Å²	89	13%	0.133	46%	0.458	C	S	.	.			trans	-99.3	88.5	174.3	-178.8	0	0	0	0	107.5	S52 V56 V105 V189 R199 I202	S52-V54 PolarHBondContact O-N 3.3Å; V54-V56 HydrophobicContact CG1-CB 4.49Å; V54-V56 HydrophobicContact CG1-CG2 3.8Å; V54-V56 PolarHBondContact O-N 3.45Å; V54-V105 HydrophobicContact CG1-CG1 4.27Å; V54-V189 HydrophobicContact CG1-CG1 4.12Å; V54-R199 PolarHBondContact O-NH1 2.99Å; V54-R199 VanDerWaalsContact O-NH1 3.09Å; V54-I202 HydrophobicContact CG1-CD1 4.23Å; V54-I202 HydrophobicContact CG2-CB 4.38Å; V54-I202 HydrophobicContact CG2-CD1 3.83Å; V54-I202 HydrophobicContact CG2-CG2 3.8Å
55	N	80.5	Confident	70.1	Confident	105 Å²	105	87.3 Å²	87.3	56%	0.561	46%	0.462	S	S	*	.			trans	-72.9	42.3	-173.2	-66.5	-25.8	0	0	0	114.6	N102	N55-N102 PolarHBondContact O-ND2 2.56Å
56	V	80.2	Confident	68.5	Low	5 Å²	5	90.3 Å²	90.3	3%	0.03	48%	0.478	C	S	.	.	P	Polyproline II helix	trans	-87.4	123.3	172.7	-179.9	0	0	0	0	108.4	V54 L100 V105 V189 R199	V54-V56 HydrophobicContact CG1-CB 4.49Å; V54-V56 HydrophobicContact CG1-CG2 3.8Å; V54-V56 PolarHBondContact O-N 3.45Å; V56-L100 HydrophobicContact CG1-CD2 4.4Å; V56-L100 HydrophobicContact CG2-CD2 3.86Å; V56-V105 HydrophobicContact CG2-CG2 3.85Å; V56-V189 HydrophobicContact CB-CG1 3.83Å; V56-V189 HydrophobicContact CG1-CG1 4.07Å; V56-V189 HydrophobicContact CG2-CG1 4.02Å; V56-R199 PolarHBondContact O-NH1 3.17Å; V56-R199 VanDerWaalsContact O-NH1 3.07Å; V56-R199 PolarHBondContact O-NH2 3.4Å
57	P	79.7	Confident	67	Low	42 Å²	42	94.4 Å²	94.4	27%	0.273	50%	0.497	S	S	.	.	P	Polyproline II helix	trans	-69.2	152.9	-178.1	31.3	-38.1	0	0	0	112.1	V97 P101 P193	P57-V97 HydrophobicContact CG-CG1 4.28Å; P57-P101 HydrophobicContact CG-CG 3.71Å; P57-P193 WeakPolarHBondContact O-CB 3.48Å
58	Y	76.8	Confident	65.9	Low	119 Å²	119	99 Å²	99	47%	0.467	52%	0.523	S	S	.	.	P	Polyproline II helix	trans	-73.1	146.1	165.4	-68.1	-91.6	0	0	0	109.8	V60 P193 E196 R199	Y58-V60 PolarHBondContact O-N 3.44Å; Y58-P193 VanDerWaalsContact CD1-O 3.27Å; Y58-P193 WeakPolarHBondContact CD1-O 3.38Å; Y58-P193 WeakPolarHBondContact CE1-O 3.4Å; Y58-E196 WeakPolarHBondContact CE1-OE1 3.48Å; Y58-E196 PolarHBondContact OH-OE1 3.38Å; Y58-E196 VanDerWaalsContact OH-OE1 3.05Å; Y58-E196 PolarHBondContact OH-OE2 3.08Å; Y58-R199 WeakPolarHBondContact OH-CD 3.46Å; Y58-R199 PolarHBondContact OH-NE 2.99Å
59	P	70.8	Confident	64.8	Low	47 Å²	47	94 Å²	94	31%	0.305	52%	0.524	S	S	.	.	P	Polyproline II helix	trans	-68.5	122.5	175.3	27.8	-24.9	0	0	0	107.5	N61 P193	P59-N61 PolarHBondContact O-N 3.11Å; P59-P193 HydrophobicContact CB-CG 4.47Å; P59-P193 HydrophobicContact CG-CG 3.82Å
60	V	65.2	Low	63.4	Low	117 Å²	117	90.4 Å²	90.4	71%	0.709	53%	0.534	S	S	*	.	P	Polyproline II helix	trans	-64.4	122.9	176.2	-173.8	0	0	0	0	107.6	Y58 P62	Y58-V60 PolarHBondContact O-N 3.44Å; V60-P62 VanDerWaalsContact O-CD 3.24Å; V60-P62 WeakPolarHBondContact O-CD 3.11Å
61	N	60.2	Low	61.4	Low	118 Å²	118	98 Å²	98	63%	0.631	57%	0.574	S	S	*	*	P	Polyproline II helix	trans	-59.8	118.5	174.9	-103.7	-16.6	0	0	0	108.9	P59 H63 N64	P59-N61 PolarHBondContact O-N 3.11Å; N61-H63 PolarHBondContact O-N 2.94Å; N61-N64 PolarHBondContact O-N 3.24Å
62	P	58.7	Low	59.6	Low	103 Å²	103	104.2 Å²	104.2	67%	0.669	61%	0.606	S	S	*	*	G	3₁₀ helix	trans	-60.2	-19.4	-178.9	-22.9	33	0	0	0	113.5	V60	V60-P62 VanDerWaalsContact O-CD 3.24Å; V60-P62 WeakPolarHBondContact O-CD 3.11Å
63	H	55.7	Low	57.5	Low	162 Å²	162	110.6 Å²	110.6	75%	0.75	64%	0.638	S	S	*	*	G	3₁₀ helix	trans	-81.7	-11.4	-176.8	-92.7	-71.8	0	0	0	115.9	N61	N61-H63 PolarHBondContact O-N 2.94Å
64	N	49.6	Very low	55.8	Low	140 Å²	140	109.8 Å²	109.8	75%	0.749	64%	0.642	S	S	*	*	G	3₁₀ helix	trans	-99.2	5	180	-78.3	6.6	0	0	0	114.2	N61	N61-N64 PolarHBondContact O-N 3.24Å
65	S	46.3	Very low	53.7	Low	91 Å²	91	116.2 Å²	116.2	64%	0.636	68%	0.676	S	S	*	*	S	Bend	trans	-101.3	13.5	179	-55.1	0	0	0	0	113.8
66	L	43.2	Very low	51.9	Low	141 Å²	141	119.6 Å²	119.6	74%	0.738	69%	0.693	S	S	*	*	S	Bend	trans	-116.7	31.4	-175.4	-115.5	97.1	0	0	0	114.3
67	H	42.6	Very low	49.8	Very low	176 Å²	176	123.6 Å²	123.6	82%	0.815	72%	0.721	S	S	*	*	S	Bend	trans	-143.2	71	172.5	-67.5	-60.6	0	0	0	112
68	S	37.5	Very low	47.8	Very low	133 Å²	133	128.9 Å²	128.9	93%	0.93	75%	0.747	S	S	*	*			trans	-168	92.4	156.5	-87.4	0	0	0	0	108.9
69	G	42.3	Very low	46.1	Very low	80 Å²	80	127.7 Å²	127.7	83%	0.825	76%	0.762	S	S	*	*			trans	167.9	90.3	174.5	0	0	0	0	0	114.3
70	G	39	Very low	44.4	Very low	78 Å²	78	130 Å²	130	80%	0.804	79%	0.785	S	S	*	*			trans	82.9	106.1	139.2	0	0	0	0	0	118
71	D	37.4	Very low	43.2	Very low	162 Å²	162	130.3 Å²	130.3	87%	0.866	78%	0.783	S	S	*	*			trans	-45.7	137.1	152.3	-62.1	-51.4	0	0	0	111.9
72	M	44.3	Very low	42.2	Very low	188 Å²	188	132.7 Å²	132.7	93%	0.926	79%	0.787	S	S	*	*			trans	177.6	126.5	134.3	-88.2	-113.4	-164.2	0	0	110.7
73	D	38.1	Very low	41.2	Very low	162 Å²	162	135.8 Å²	135.8	87%	0.866	80%	0.797	S	S	*	*			trans	-51.6	144	172.5	-64.8	-56.8	0	0	0	114.1
74	S	42.5	Very low	40.3	Very low	114 Å²	114	134.5 Å²	134.5	80%	0.797	80%	0.801	S	S	*	*				-178.7	125.9	123.4	58.8	0	0	0	0	111.7
75	D	36.7	Very low	39.6	Very low	158 Å²	158	135.1 Å²	135.1	85%	0.845	80%	0.804	S	S	*	*			trans	-40.3	139.4	164.4	-74.1	-51.6	0	0	0	114.3
76	L	44.1	Very low	38.9	Very low	176 Å²	176	137.9 Å²	137.9	92%	0.921	81%	0.812	S	S	*	*			trans	-162.9	113.4	137.4	-102.2	147.6	0	0	0	111
77	S	36.3	Very low	38.6	Very low	88 Å²	88	139.9 Å²	139.9	62%	0.615	82%	0.815	S	S	*	*			trans	-72.6	155.3	178.5	55.2	0	0	0	0	114.5
78	N	36.6	Very low	38.2	Very low	153 Å²	153	138.9 Å²	138.9	82%	0.818	81%	0.81	S	S	*	*			trans	90.1	109.7	148.6	-55.4	-32.9	0	0	0	119.7
79	A	41.1	Very low	38.1	Very low	95 Å²	95	142.2 Å²	142.2	79%	0.785	81%	0.811	S	S	*	*				166	102.7	124	0	0	0	0	0	108.2
80	A	35.4	Very low	38.1	Very low	95 Å²	95	146.1 Å²	146.1	79%	0.785	81%	0.806	S	S	*	*				54	100.4	97.6	0	0	0	0	0	113.2
81	D	39.1	Very low	38.2	Very low	124 Å²	124	147.5 Å²	147.5	66%	0.663	80%	0.801	S	S	*	*				173.8	131.1	99.8	-122.2	-11.6	0	0	0	111.8
82	K	40	Very low	38.6	Very low	168 Å²	168	145.6 Å²	145.6	73%	0.73	80%	0.8	S	S	*	*			trans	53.7	105.7	142.2	-69.4	161.9	-167.3	140.8	0	120.6
83	L	37.1	Very low	39.1	Very low	168 Å²	168	145.5 Å²	145.5	88%	0.88	79%	0.794	S	S	*	*			trans	-43.5	130	138.5	-72.8	120.1	0	0	0	111.9
84	T	36.8	Very low	39.8	Very low	134 Å²	134	139.1 Å²	139.1	82%	0.822	77%	0.766	S	S	*	*				-179.1	126.8	123.9	44.4	0	0	0	0	111.5
85	N	35.8	Very low	40.6	Very low	153 Å²	153	137.8 Å²	137.8	82%	0.818	76%	0.757	S	S	*	*			trans	30.6	111.6	150.7	-77.7	-8.6	0	0	0	119.9
86	D	32.1	Very low	41.5	Very low	149 Å²	149	133.4 Å²	133.4	80%	0.797	73%	0.731	S	S	*	*				154.1	115.8	119.1	-99	-24.8	0	0	0	108.8
87	K	35.9	Very low	42.1	Very low	183 Å²	183	126.6 Å²	126.6	80%	0.796	70%	0.696	S	S	*	*			trans	160.9	101.8	137.9	-84.5	155.5	-168.9	-179.5	0	111.7
88	Q	34.5	Very low	43.2	Very low	155 Å²	155	132 Å²	132	72%	0.724	71%	0.705	S	S	*	*				57.8	79.7	128.3	-63.7	172.2	-24.4	0	0	117.4	F90	Q88-F90 HydrophobicContact CB-CD2 3.98Å; Q88-F90 HydrophobicContact CB-CE2 4.01Å; Q88-F90 HydrophobicContact CG-CD2 4.35Å; Q88-F90 HydrophobicContact CG-CE2 3.86Å; Q88-F90 PolarHBondContact O-N 3.13Å
89	Q	35.4	Very low	44.6	Very low	204 Å²	204	127.9 Å²	127.9	95%	0.953	69%	0.692	S	S	*	*			trans	-92.5	86.1	151.9	-96.9	174.3	-8	0	0	109.1
90	F	42.9	Very low	46.1	Very low	161 Å²	161	126.5 Å²	126.5	71%	0.706	67%	0.671	S	S	*	*			trans	-67.2	147.7	163.4	-81.1	-84.4	0	0	0	109.6	Q88 S92	Q88-F90 HydrophobicContact CB-CD2 3.98Å; Q88-F90 HydrophobicContact CB-CE2 4.01Å; Q88-F90 HydrophobicContact CG-CD2 4.35Å; Q88-F90 HydrophobicContact CG-CE2 3.86Å; Q88-F90 PolarHBondContact O-N 3.13Å; F90-S92 PolarHBondContact O-N 3.37Å
91	P	40.3	Very low	47.7	Very low	108 Å²	108	126.4 Å²	126.4	70%	0.701	66%	0.662	S	S	*	*			trans	-61.9	140	-171.2	26.9	-33.5	0	0	0	110.1	K93	P91-K93 PolarHBondContact O-N 3.38Å
92	S	45.6	Very low	49.3	Very low	121 Å²	121	125.9 Å²	125.9	85%	0.846	66%	0.659	S	S	*	*			trans	-44.5	91.1	174.5	41.5	0	0	0	0	111.9	F90 G94	F90-S92 PolarHBondContact O-N 3.37Å; S92-G94 PolarHBondContact O-N 3.14Å
93	K	54	Low	51	Low	187 Å²	187	119.9 Å²	119.9	81%	0.813	65%	0.645	S	S	*	*			trans	-62	107.7	161.6	-82.2	179.9	176.2	175.4	0	106	P91 S95	P91-K93 PolarHBondContact O-N 3.38Å; K93-S95 PolarHBondContact O-N 3.49Å
94	G	54.3	Low	53.2	Low	27 Å²	27	117 Å²	117	28%	0.278	64%	0.639	S	S	.	*			trans	-46.8	130.5	174	0	0	0	0	0	109.8	S92 F96	S92-G94 PolarHBondContact O-N 3.14Å; G94-F96 PolarHBondContact O-N 3.44Å
95	S	58.3	Low	55.6	Low	86 Å²	86	112.3 Å²	112.3	60%	0.601	61%	0.611	S	S	*	*			trans	-58	113	-178.4	-172.1	0	0	0	0	108.8	K93 V97	K93-S95 PolarHBondContact O-N 3.49Å; S95-V97 PolarHBondContact O-N 3.23Å
96	F	55.1	Low	58.2	Low	67 Å²	67	107.7 Å²	107.7	29%	0.294	59%	0.59	S	S	.	*			trans	-59	132.8	173.8	-68.5	-79.2	0	0	0	108.5	G94 Y98 K191	G94-F96 PolarHBondContact O-N 3.44Å; F96-Y98 VanDerWaalsContact C-N 3.29Å; F96-Y98 HydrophobicContact CB-CD2 3.95Å; F96-Y98 HydrophobicContact CB-CE1 4.27Å; F96-Y98 HydrophobicContact CB-CE2 3.64Å; F96-Y98 HydrophobicContact CB-CG 4.4Å; F96-Y98 HydrophobicContact CD2-CE2 4.36Å; F96-Y98 HydrophobicContact CG-CE2 4.44Å; F96-Y98 VanDerWaalsContact O-CD2 3.29Å; F96-Y98 WeakPolarHBondContact O-CD2 3.29Å; F96-Y98 PolarHBondContact O-N 2.84Å; F96-K191 HydrophobicContact CD1-CB 3.87Å; F96-K191 HydrophobicContact CD1-CG 3.88Å; F96-K191 HydrophobicContact CE1-CB 3.97Å; F96-K191 HydrophobicContact CE1-CD 4.36Å; F96-K191 HydrophobicContact CE1-CG 4.03Å
97	V	57.2	Low	61	Low	32 Å²	32	106.1 Å²	106.1	19%	0.194	57%	0.574	C	S	.	*			trans	-77	89.6	168.2	176.8	0	0	0	0	106.5	P57 S95 A99 A190 P193	P57-V97 HydrophobicContact CG-CG1 4.28Å; S95-V97 PolarHBondContact O-N 3.23Å; V97-A99 WeakPolarHBondContact CG1-O 3.04Å; V97-A99 PolarHBondContact O-N 2.83Å; V97-A190 WeakPolarHBondContact CB-O 3.47Å; V97-A190 PolarHBondContact N-O 3.33Å; V97-P193 HydrophobicContact CG2-CB 4.37Å; V97-P193 HydrophobicContact CG2-CG 3.79Å
98	Y	60.5	Low	63.8	Low	202 Å²	202	97.6 Å²	97.6	79%	0.792	54%	0.537	S	S	*	.			trans	-70.2	-12.4	-179.3	-74.6	-78.5	0	0	0	113.4	F96	F96-Y98 VanDerWaalsContact C-N 3.29Å; F96-Y98 HydrophobicContact CB-CD2 3.95Å; F96-Y98 HydrophobicContact CB-CE1 4.27Å; F96-Y98 HydrophobicContact CB-CE2 3.64Å; F96-Y98 HydrophobicContact CB-CG 4.4Å; F96-Y98 HydrophobicContact CD2-CE2 4.36Å; F96-Y98 HydrophobicContact CG-CE2 4.44Å; F96-Y98 VanDerWaalsContact O-CD2 3.29Å; F96-Y98 WeakPolarHBondContact O-CD2 3.29Å; F96-Y98 PolarHBondContact O-N 2.84Å
99	A	65	Low	66.6	Low	67 Å²	67	97.6 Å²	97.6	55%	0.554	54%	0.535	S	S	*	.	S	Bend	trans	-136.6	135.6	178.3	0	0	0	0	0	109.5	V97 P101	V97-A99 WeakPolarHBondContact CG1-O 3.04Å; V97-A99 PolarHBondContact O-N 2.83Å; A99-P101 WeakPolarHBondContact O-CD 3.23Å
100	L	73	Confident	69.4	Low	66 Å²	66	90 Å²	90	35%	0.346	50%	0.499	S	S	.	.			trans	-85.3	96.3	167.7	-64.4	171.3	0	0	0	107.6	V56 N102 G103 V105 A190	V56-L100 HydrophobicContact CG1-CD2 4.4Å; V56-L100 HydrophobicContact CG2-CD2 3.86Å; L100-N102 PolarHBondContact O-N 2.78Å; L100-N102 VanDerWaalsContact O-N 3.09Å; L100-G103 WeakPolarHBondContact CB-O 3.31Å; L100-G103 PolarHBondContact O-N 3.18Å; L100-V105 HydrophobicContact CD1-CG2 4.13Å; L100-V105 HydrophobicContact CD2-CG2 4.33Å; L100-A190 HydrophobicContact CD2-CB 4.47Å
101	P	67.8	Low	71.9	Confident	92 Å²	92	82.3 Å²	82.3	60%	0.597	47%	0.465	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.5	-21.6	-172.5	26.6	-35.8	0	0	0	112.8	P57 A99 G103	P57-P101 HydrophobicContact CG-CG 3.71Å; A99-P101 WeakPolarHBondContact O-CD 3.23Å; P101-G103 VanDerWaalsContact C-N 3.34Å
102	N	72.9	Confident	74.5	Confident	113 Å²	113	79.8 Å²	79.8	60%	0.604	44%	0.443	S	S	*	.	T	Hydrogen-bonded Turn	trans	-92.3	12.3	179.5	-59.4	-28.5	0	0	0	113.4	N55 L100	N55-N102 PolarHBondContact O-ND2 2.56Å; L100-N102 PolarHBondContact O-N 2.78Å; L100-N102 VanDerWaalsContact O-N 3.09Å
103	G	77	Confident	76.9	Confident	42 Å²	42	75.5 Å²	75.5	43%	0.433	42%	0.416	S	S	.	.			trans	82.3	-159	-175.4	0	0	0	0	0	113.4	L100 P101	L100-G103 WeakPolarHBondContact CB-O 3.31Å; L100-G103 PolarHBondContact O-N 3.18Å; P101-G103 VanDerWaalsContact C-N 3.34Å
104	S	83.6	Confident	78.9	Confident	108 Å²	108	66.6 Å²	66.6	76%	0.755	38%	0.377	S	S	*	.	P	Polyproline II helix	trans	-70.4	137.8	-176.5	59.7	0	0	0	0	112.6	S106	S104-S106 PolarHBondContact O-N 3.35Å
105	V	86.9	Confident	80.9	Confident	36 Å²	36	65.4 Å²	65.4	22%	0.218	36%	0.364	C	S	.	.	P	Polyproline II helix	trans	-69.3	118.4	166.6	179.8	0	0	0	0	108.9	V54 V56 L100 V186	V54-V105 HydrophobicContact CG1-CG1 4.27Å; V56-V105 HydrophobicContact CG2-CG2 3.85Å; L100-V105 HydrophobicContact CD1-CG2 4.13Å; L100-V105 HydrophobicContact CD2-CG2 4.33Å; V105-V186 HydrophobicContact CB-CG1 3.83Å; V105-V186 HydrophobicContact CG1-CG1 3.87Å; V105-V186 HydrophobicContact CG1-CG2 4.15Å; V105-V186 HydrophobicContact CG2-CG1 3.9Å
106	S	90	Very high	82.8	Confident	56 Å²	56	66.4 Å²	66.4	39%	0.392	36%	0.359	S	S	.	.	P	Polyproline II helix	trans	-72	158	-178.7	-157.2	0	0	0	0	112.2	S104 R182	S104-S106 PolarHBondContact O-N 3.35Å; S106-R182 PolarHBondContact O-NH1 3.47Å
107	Y	91.7	Very high	84.8	Confident	115 Å²	115	68 Å²	68	45%	0.451	37%	0.366	S	S	.	.	P	Polyproline II helix	trans	-70.7	160.7	165.7	53.5	-102.3	0	0	0	110.2	K109 K112	Y107-K109 HydrophobicContact CD2-CG 4.49Å; Y107-K109 HydrophobicContact CE2-CG 4.11Å; Y107-K109 PolarHBondContact O-N 3.19Å; Y107-K112 HydrophobicContact CD2-CB 4.03Å; Y107-K112 HydrophobicContact CD2-CD 3.62Å; Y107-K112 HydrophobicContact CD2-CG 4.45Å; Y107-K112 HydrophobicContact CE1-CD 4.33Å; Y107-K112 HydrophobicContact CE2-CB 4.2Å; Y107-K112 HydrophobicContact CE2-CD 3.13Å; Y107-K112 HydrophobicContact CE2-CG 4.29Å; Y107-K112 HydrophobicContact CG-CD 4.41Å
108	N	94	Very high	86.7	Confident	5 Å²	5	66.6 Å²	66.6	3%	0.027	36%	0.357	C	S	.	.			trans	-71.5	113.1	173.8	-171.3	-46.1	0	0	0	110.1	V50 S52 H110 I111 K112 D206	V50-N108 PolarHBondContact O-ND2 2.87Å; S52-N108 WeakPolarHBondContact CB-ND2 3.44Å; N108-H110 PolarHBondContact OD1-N 3.18Å; N108-H110 VanDerWaalsContact OD1-N 3.15Å; N108-I111 HydrophobicContact CB-CB 4.03Å; N108-I111 HydrophobicContact CB-CG1 4.02Å; N108-I111 PolarHBondContact OD1-N 3.36Å; N108-I111 VanDerWaalsContact OD1-N 3.16Å; N108-K112 WeakPolarHBondContact O-CB 3.13Å; N108-K112 PolarHBondContact O-N 2.73Å; N108-D206 PolarHBondContact ND2-OD2 3.16Å
109	K	93.2	Very high	88.4	Confident	155 Å²	155	60.7 Å²	60.7	67%	0.674	34%	0.336	S	S	*	.	H	α-helix	trans	-66.9	-37.5	-174.1	-65.7	-178.7	-178.3	176	0	112.8	Y107 K112 A113	Y107-K109 HydrophobicContact CD2-CG 4.49Å; Y107-K109 HydrophobicContact CE2-CG 4.11Å; Y107-K109 PolarHBondContact O-N 3.19Å; K109-K112 PolarHBondContact O-N 2.91Å; K109-A113 PolarHBondContact O-N 3.43Å
110	H	93.6	Very high	90	Very high	43 Å²	43	61.2 Å²	61.2	20%	0.199	33%	0.333	C	S	.	.	H	α-helix	trans	-67.2	-49.6	179.1	-179.2	78	0	0	0	110.5	M42 N108 K112 A113 M114	M42-H110 PolarHBondContact O-CE1 3.45Å; M42-H110 VanDerWaalsContact O-CE1 3.27Å; M42-H110 PolarHBondContact O-NE2 3.37Å; N108-H110 PolarHBondContact OD1-N 3.18Å; N108-H110 VanDerWaalsContact OD1-N 3.15Å; H110-K112 VanDerWaalsContact C-N 3.29Å; H110-K112 PolarHBondContact O-N 3.39Å; H110-A113 WeakPolarHBondContact O-CB 3.38Å; H110-A113 PolarHBondContact O-N 3.02Å; H110-A113 VanDerWaalsContact O-N 3.07Å; H110-M114 WeakPolarHBondContact O-CG 3.37Å; H110-M114 PolarHBondContact O-N 2.92Å
111	I	95	Very high	91.2	Very high	0 Å²	0	59 Å²	59	0%	0	32%	0.323	C	S	.	.	H	α-helix	trans	-59.8	-40.2	175.6	-61.9	-60.7	0	0	0	111.9	V50 N108 A113 M114 I115 Y178 D206 Q209 A210	V50-I111 HydrophobicContact CG1-CD1 3.88Å; V50-I111 HydrophobicContact CG1-CG1 4.48Å; N108-I111 HydrophobicContact CB-CB 4.03Å; N108-I111 HydrophobicContact CB-CG1 4.02Å; N108-I111 PolarHBondContact OD1-N 3.36Å; N108-I111 VanDerWaalsContact OD1-N 3.16Å; I111-A113 VanDerWaalsContact C-N 3.34Å; I111-A113 PolarHBondContact O-N 3.42Å; I111-M114 HydrophobicContact CD1-SD 4.12Å; I111-M114 PolarHBondContact O-N 3.47Å; I111-I115 HydrophobicContact CG2-CD1 3.74Å; I111-I115 HydrophobicContact CG2-CG1 4.38Å; I111-I115 WeakPolarHBondContact O-CB 3.48Å; I111-I115 VanDerWaalsContact O-CG1 3.31Å; I111-I115 WeakPolarHBondContact O-CG1 3.36Å; I111-I115 PolarHBondContact O-N 2.89Å; I111-Y178 HydrophobicContact CB-CE1 4.35Å; I111-Y178 HydrophobicContact CG2-CD1 4.13Å; I111-Y178 HydrophobicContact CG2-CE1 3.42Å; I111-Y178 VanDerWaalsContact CG2-CE1 3.42Å; I111-Y178 HydrophobicContact CG2-CE2 4.35Å; I111-D206 WeakPolarHBondContact CD1-O 3.41Å; I111-Q209 HydrophobicContact CD1-CB 4.22Å; I111-Q209 HydrophobicContact CD1-CG 4.41Å; I111-Q209 HydrophobicContact CG2-CB 4.24Å; I111-Q209 HydrophobicContact CG2-CG 3.51Å; I111-A210 HydrophobicContact CD1-CB 3.66Å
112	K	95.7	Very high	92.6	Very high	55 Å²	55	54.7 Å²	54.7	24%	0.239	30%	0.295	C	S	.	.	H	α-helix	trans	-59.2	-45.4	174.4	177.7	178.5	169	48.9	0	111.5	Y107 N108 K109 H110 I115 E116	Y107-K112 HydrophobicContact CD2-CB 4.03Å; Y107-K112 HydrophobicContact CD2-CD 3.62Å; Y107-K112 HydrophobicContact CD2-CG 4.45Å; Y107-K112 HydrophobicContact CE1-CD 4.33Å; Y107-K112 HydrophobicContact CE2-CB 4.2Å; Y107-K112 HydrophobicContact CE2-CD 3.13Å; Y107-K112 HydrophobicContact CE2-CG 4.29Å; Y107-K112 HydrophobicContact CG-CD 4.41Å; N108-K112 WeakPolarHBondContact O-CB 3.13Å; N108-K112 PolarHBondContact O-N 2.73Å; K109-K112 PolarHBondContact O-N 2.91Å; H110-K112 VanDerWaalsContact C-N 3.29Å; H110-K112 PolarHBondContact O-N 3.39Å; K112-I115 WeakPolarHBondContact O-CB 3.28Å; K112-I115 PolarHBondContact O-N 2.85Å; K112-E116 VanDerWaalsContact CE-OE1 3.31Å; K112-E116 WeakPolarHBondContact CE-OE1 3.44Å; K112-E116 HydrophobicContact CG-CG 4.38Å; K112-E116 IonicContact NZ-OE1 3.26Å; K112-E116 PolarHBondContact NZ-OE1 3.41Å; K112-E116 IonicContact NZ-OE2 3.59Å; K112-E116 WeakPolarHBondContact O-CG 3.43Å; K112-E116 PolarHBondContact O-N 3.17Å
113	A	95.5	Very high	93.7	Very high	32 Å²	32	51.9 Å²	51.9	26%	0.264	28%	0.283	S	S	.	.	H	α-helix	trans	-62.2	-43.2	178.3	0	0	0	0	0	111.8	M42 K109 H110 I111 I115 E116 K117	M42-A113 HydrophobicContact CE-CB 4.16Å; M42-A113 HydrophobicContact SD-CB 4.48Å; K109-A113 PolarHBondContact O-N 3.43Å; H110-A113 WeakPolarHBondContact O-CB 3.38Å; H110-A113 PolarHBondContact O-N 3.02Å; H110-A113 VanDerWaalsContact O-N 3.07Å; I111-A113 VanDerWaalsContact C-N 3.34Å; I111-A113 PolarHBondContact O-N 3.42Å; A113-I115 PolarHBondContact O-N 3.22Å; A113-E116 PolarHBondContact O-N 3.32Å; A113-K117 PolarHBondContact O-N 3.09Å
114	M	96.6	Very high	94.7	Very high	0 Å²	0	53.1 Å²	53.1	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-58.1	-48.2	173.2	-62.7	179.1	89.3	0	0	111.1	M42 F43 H110 I111 E116 K117 T118 A210 M213	M42-M114 HydrophobicContact CG-CG 3.96Å; F43-M114 HydrophobicContact CD1-CE 3.46Å; F43-M114 VanDerWaalsContact CD1-CE 3.46Å; F43-M114 HydrophobicContact CE1-CB 4.4Å; F43-M114 HydrophobicContact CE1-CE 3.69Å; F43-M114 HydrophobicContact CG-CE 4.16Å; F43-M114 HydrophobicContact CZ-CB 4.28Å; H110-M114 WeakPolarHBondContact O-CG 3.37Å; H110-M114 PolarHBondContact O-N 2.92Å; I111-M114 HydrophobicContact CD1-SD 4.12Å; I111-M114 PolarHBondContact O-N 3.47Å; M114-E116 VanDerWaalsContact C-N 3.33Å; M114-E116 PolarHBondContact O-N 2.97Å; M114-K117 PolarHBondContact O-N 3.1Å; M114-K117 VanDerWaalsContact O-N 3.16Å; M114-T118 WeakPolarHBondContact O-CB 3.36Å; M114-T118 PolarHBondContact O-N 3.41Å; M114-T118 PolarHBondContact O-OG1 3.28Å; M114-A210 HydrophobicContact CE-CB 4.31Å; M114-A210 WeakPolarHBondContact CE-O 3.42Å; M114-A210 HydrophobicContact SD-CB 3.96Å; M114-M213 HydrophobicContact CB-CB 3.99Å; M114-M213 HydrophobicContact CB-CG 3.96Å; M114-M213 HydrophobicContact CE-CB 3.77Å; M114-M213 HydrophobicContact SD-CB 4.25Å
115	I	97.2	Very high	95.4	Very high	2 Å²	2	48.1 Å²	48.1	1%	0.01	24%	0.242	C	C	.	.	H	α-helix	trans	-58	-44.3	177.4	-75.8	165.3	0	0	0	111.7	I111 K112 A113 K117 T118 K119 V175 Y178 Y179 M213	I111-I115 HydrophobicContact CG2-CD1 3.74Å; I111-I115 HydrophobicContact CG2-CG1 4.38Å; I111-I115 WeakPolarHBondContact O-CB 3.48Å; I111-I115 VanDerWaalsContact O-CG1 3.31Å; I111-I115 WeakPolarHBondContact O-CG1 3.36Å; I111-I115 PolarHBondContact O-N 2.89Å; K112-I115 WeakPolarHBondContact O-CB 3.28Å; K112-I115 PolarHBondContact O-N 2.85Å; A113-I115 PolarHBondContact O-N 3.22Å; I115-K117 VanDerWaalsContact C-N 3.27Å; I115-K117 PolarHBondContact O-N 3.38Å; I115-T118 PolarHBondContact O-N 2.9Å; I115-K119 HydrophobicContact CG2-CD 3.86Å; I115-K119 HydrophobicContact CG2-CG 4.14Å; I115-K119 WeakPolarHBondContact O-CB 3.4Å; I115-K119 WeakPolarHBondContact O-CG 3.28Å; I115-K119 PolarHBondContact O-N 3.06Å; I115-V175 HydrophobicContact CB-CG1 4.32Å; I115-V175 HydrophobicContact CD1-CG1 3.86Å; I115-V175 HydrophobicContact CG1-CG1 3.87Å; I115-V175 HydrophobicContact CG2-CG1 3.5Å; I115-V175 VanDerWaalsContact CG2-CG1 3.5Å; I115-Y178 HydrophobicContact CD1-CD1 3.99Å; I115-Y178 HydrophobicContact CD1-CE1 4.31Å; I115-Y179 HydrophobicContact CD1-CE2 3.8Å; I115-Y179 WeakPolarHBondContact CD1-OH 3.4Å; I115-M213 HydrophobicContact CB-SD 4.33Å; I115-M213 HydrophobicContact CG1-CG 4.3Å; I115-M213 HydrophobicContact CG1-SD 3.4Å; I115-M213 WeakPolarHBondContact CG1-SD 3.5Å
116	E	97.2	Very high	95.8	Very high	107 Å²	107	48.8 Å²	48.8	50%	0.5	24%	0.243	S	C	.	.	H	α-helix	trans	-67.1	-28.8	179.9	-75	177.9	152.1	0	0	112.6	K112 A113 M114 P120	K112-E116 VanDerWaalsContact CE-OE1 3.31Å; K112-E116 WeakPolarHBondContact CE-OE1 3.44Å; K112-E116 HydrophobicContact CG-CG 4.38Å; K112-E116 IonicContact NZ-OE1 3.26Å; K112-E116 PolarHBondContact NZ-OE1 3.41Å; K112-E116 IonicContact NZ-OE2 3.59Å; K112-E116 WeakPolarHBondContact O-CG 3.43Å; K112-E116 PolarHBondContact O-N 3.17Å; A113-E116 PolarHBondContact O-N 3.32Å; M114-E116 VanDerWaalsContact C-N 3.33Å; M114-E116 PolarHBondContact O-N 2.97Å; E116-P120 WeakPolarHBondContact O-CD 3.41Å; E116-P120 WeakPolarHBondContact O-CG 3.42Å
117	K	97.2	Very high	96.2	Very high	100 Å²	100	50.4 Å²	50.4	44%	0.435	25%	0.247	S	C	.	.	H	α-helix	trans	-78.1	-40.9	171.9	-171.1	63.7	175.1	-177.9	0	112.4	I37 M42 F43 A113 M114 I115 C121	I37-K117 HydrophobicContact CG2-CG 4.23Å; M42-K117 HydrophobicContact SD-CB 4Å; M42-K117 HydrophobicContact SD-CG 4.4Å; F43-K117 HydrophobicContact CE2-CB 4.3Å; F43-K117 HydrophobicContact CE2-CG 4.05Å; F43-K117 HydrophobicContact CZ-CB 4.41Å; F43-K117 HydrophobicContact CZ-CG 4.44Å; A113-K117 PolarHBondContact O-N 3.09Å; M114-K117 PolarHBondContact O-N 3.1Å; M114-K117 VanDerWaalsContact O-N 3.16Å; I115-K117 VanDerWaalsContact C-N 3.27Å; I115-K117 PolarHBondContact O-N 3.38Å; K117-C121 PolarHBondContact O-SG 2.9Å
118	T	97.4	Very high	96.5	Very high	2 Å²	2	45.4 Å²	45.4	1%	0.012	23%	0.227	C	C	.	.	H	α-helix	trans	-74.1	-42.4	-176	-58.3	0	0	0	0	113.2	M114 I115 C121 L122 I216 I217	M114-T118 WeakPolarHBondContact O-CB 3.36Å; M114-T118 PolarHBondContact O-N 3.41Å; M114-T118 PolarHBondContact O-OG1 3.28Å; I115-T118 PolarHBondContact O-N 2.9Å; T118-C121 WeakPolarHBondContact O-CB 3.5Å; T118-C121 PolarHBondContact O-N 3Å; T118-C121 VanDerWaalsContact O-N 3.17Å; T118-L122 PolarHBondContact O-N 3.12Å; T118-I216 HydrophobicContact CG2-CB 4.14Å; T118-I216 HydrophobicContact CG2-CG2 3.51Å; T118-I217 HydrophobicContact CG2-CD1 3.91Å; T118-I217 HydrophobicContact CG2-CG1 4.44Å
119	K	97.1	Very high	96.7	Very high	78 Å²	78	45.2 Å²	45.2	34%	0.339	23%	0.226	S	C	.	.	H	α-helix	trans	-56.1	-46.6	-175.1	-83.5	-177.3	176.7	-169.9	0	114.2	I115 L122 T123	I115-K119 HydrophobicContact CG2-CD 3.86Å; I115-K119 HydrophobicContact CG2-CG 4.14Å; I115-K119 WeakPolarHBondContact O-CB 3.4Å; I115-K119 WeakPolarHBondContact O-CG 3.28Å; I115-K119 PolarHBondContact O-N 3.06Å; K119-L122 PolarHBondContact O-N 3.34Å; K119-T123 WeakPolarHBondContact O-CB 3.35Å; K119-T123 PolarHBondContact O-N 3.1Å; K119-T123 PolarHBondContact O-OG1 2.64Å
120	P	97.5	Very high	96.9	Very high	78 Å²	78	42 Å²	42	51%	0.506	21%	0.214	S	C	.	.	H	α-helix	trans	-62.4	-42.1	176.7	-24.5	35.4	0	0	0	112.6	E116 L122 T123 Q124	E116-P120 WeakPolarHBondContact O-CD 3.41Å; E116-P120 WeakPolarHBondContact O-CG 3.42Å; P120-L122 VanDerWaalsContact C-N 3.31Å; P120-L122 PolarHBondContact O-N 3.41Å; P120-T123 PolarHBondContact O-N 3.08Å; P120-Q124 WeakPolarHBondContact O-CB 3.4Å; P120-Q124 PolarHBondContact O-N 3.32Å
121	C	97.9	Very high	97.1	Very high	20 Å²	20	42.2 Å²	42.2	14%	0.135	22%	0.216	C	C	.	.	H	α-helix	trans	-60.8	-43.3	178.3	-55.4	0	0	0	0	111.1	M34 K117 T118 Q124 L125 I220	M34-C121 HydrophobicContact CE-CB 4.16Å; M34-C121 HydrophobicContact SD-CB 4.04Å; K117-C121 PolarHBondContact O-SG 2.9Å; T118-C121 WeakPolarHBondContact O-CB 3.5Å; T118-C121 PolarHBondContact O-N 3Å; T118-C121 VanDerWaalsContact O-N 3.17Å; C121-Q124 WeakPolarHBondContact O-CB 3.29Å; C121-Q124 PolarHBondContact O-N 2.99Å; C121-L125 PolarHBondContact O-N 3.32Å; C121-I220 HydrophobicContact CB-CD1 3.9Å
122	L	97	Very high	97.2	Very high	1 Å²	1	42.2 Å²	42.2	1%	0.005	22%	0.216	C	C	.	.	H	α-helix	trans	-66.8	-40.9	178.2	-170	61.7	0	0	0	112.9	T118 K119 P120 Q124 L125 M126 A168 F171 L172 I216 I220	T118-L122 PolarHBondContact O-N 3.12Å; K119-L122 PolarHBondContact O-N 3.34Å; P120-L122 VanDerWaalsContact C-N 3.31Å; P120-L122 PolarHBondContact O-N 3.41Å; L122-Q124 VanDerWaalsContact C-N 3.31Å; L122-L125 PolarHBondContact O-N 3.33Å; L122-M126 PolarHBondContact O-N 3.45Å; L122-M126 VanDerWaalsContact O-N 3.1Å; L122-A168 HydrophobicContact CD1-CB 3.85Å; L122-A168 HydrophobicContact CG-CB 4.23Å; L122-F171 HydrophobicContact CD1-CB 4.22Å; L122-F171 HydrophobicContact CD1-CD2 3.99Å; L122-F171 HydrophobicContact CD2-CB 3.53Å; L122-L172 HydrophobicContact CD2-CB 4.48Å; L122-L172 HydrophobicContact CD2-CD2 3.79Å; L122-L172 HydrophobicContact CD2-CG 3.65Å; L122-L172 HydrophobicContact CG-CD2 4.44Å; L122-L172 HydrophobicContact CG-CG 4.28Å; L122-I216 HydrophobicContact CD1-CG2 4.29Å; L122-I216 HydrophobicContact CD2-CG2 4.49Å; L122-I220 HydrophobicContact CB-CD1 4.12Å; L122-I220 HydrophobicContact CD1-CD1 4.11Å; L122-I220 HydrophobicContact CD1-CG1 4.06Å
123	T	96.6	Very high	97.3	Very high	55 Å²	55	42.3 Å²	42.3	34%	0.337	22%	0.215	S	C	.	.	H	α-helix	trans	-64.5	-40.1	175.8	-55.5	0	0	0	0	110.6	K119 P120 M126 I127	K119-T123 WeakPolarHBondContact O-CB 3.35Å; K119-T123 PolarHBondContact O-N 3.1Å; K119-T123 PolarHBondContact O-OG1 2.64Å; P120-T123 PolarHBondContact O-N 3.08Å; T123-M126 PolarHBondContact O-N 3.09Å; T123-I127 HydrophobicContact CG2-CD1 4.03Å; T123-I127 WeakPolarHBondContact O-CG1 3.45Å; T123-I127 PolarHBondContact O-N 3.04Å; T123-I127 VanDerWaalsContact O-N 3.08Å
124	Q	97.7	Very high	97.4	Very high	67 Å²	67	42.6 Å²	42.6	31%	0.313	21%	0.212	S	C	.	.	H	α-helix	trans	-63.3	-46.3	176.4	-170.2	63.2	43.4	0	0	111.5	P120 C121 L122 M126 I127 E128	P120-Q124 WeakPolarHBondContact O-CB 3.4Å; P120-Q124 PolarHBondContact O-N 3.32Å; C121-Q124 WeakPolarHBondContact O-CB 3.29Å; C121-Q124 PolarHBondContact O-N 2.99Å; L122-Q124 VanDerWaalsContact C-N 3.31Å; Q124-M126 VanDerWaalsContact C-N 3.3Å; Q124-M126 PolarHBondContact O-N 3.15Å; Q124-I127 PolarHBondContact O-N 3.17Å; Q124-E128 HydrophobicContact CG-CG 4.36Å; Q124-E128 WeakPolarHBondContact CG-OE1 3.22Å; Q124-E128 VanDerWaalsContact NE2-CD 3.33Å; Q124-E128 PolarHBondContact NE2-OE1 3.41Å; Q124-E128 WeakPolarHBondContact O-CB 3.1Å; Q124-E128 WeakPolarHBondContact O-CG 3.39Å; Q124-E128 PolarHBondContact O-N 2.99Å
125	L	98.1	Very high	97.4	Very high	4 Å²	4	42.7 Å²	42.7	2%	0.021	21%	0.212	C	C	.	.	H	α-helix	trans	-54.7	-46.4	174.8	177.2	69.3	0	0	0	111.5	C121 L122 E128 A129 I164 I220 H223 Y224	C121-L125 PolarHBondContact O-N 3.32Å; L122-L125 PolarHBondContact O-N 3.33Å; L125-E128 PolarHBondContact O-N 3.26Å; L125-A129 VanDerWaalsContact O-CB 3.25Å; L125-A129 WeakPolarHBondContact O-CB 3.35Å; L125-A129 PolarHBondContact O-N 3.36Å; L125-I164 HydrophobicContact CD1-CG2 3.83Å; L125-I164 HydrophobicContact CD2-CG2 3.81Å; L125-I164 HydrophobicContact CG-CG2 3.66Å; L125-I220 HydrophobicContact CB-CG2 4.36Å; L125-I220 HydrophobicContact CD2-CB 4.32Å; L125-I220 HydrophobicContact CD2-CG1 3.95Å; L125-I220 HydrophobicContact CD2-CG2 4.28Å; L125-H223 HydrophobicContact CD1-CB 4.1Å; L125-H223 HydrophobicContact CD2-CB 4.28Å; L125-Y224 WeakPolarHBondContact CA-OH 3.42Å; L125-Y224 HydrophobicContact CB-CE2 4.37Å; L125-Y224 HydrophobicContact CD1-CD1 4.07Å; L125-Y224 HydrophobicContact CD1-CD2 4.13Å; L125-Y224 HydrophobicContact CD1-CE1 3.74Å; L125-Y224 HydrophobicContact CD1-CE2 3.8Å; L125-Y224 HydrophobicContact CD1-CG 4.26Å; L125-Y224 PolarHBondContact N-OH 2.98Å
126	M	96.7	Very high	97.5	Very high	50 Å²	50	42.7 Å²	42.7	25%	0.246	21%	0.212	C	C	.	.	H	α-helix	trans	-61.9	-44.4	179.3	-174.6	179	65.3	0	0	112.4	L122 T123 Q124 Q130 A168	L122-M126 PolarHBondContact O-N 3.45Å; L122-M126 VanDerWaalsContact O-N 3.1Å; T123-M126 PolarHBondContact O-N 3.09Å; Q124-M126 VanDerWaalsContact C-N 3.3Å; Q124-M126 PolarHBondContact O-N 3.15Å; M126-Q130 WeakPolarHBondContact O-CB 3.48Å; M126-Q130 PolarHBondContact O-N 2.88Å; M126-Q130 VanDerWaalsContact O-N 3.08Å; M126-A168 HydrophobicContact CB-CB 4.06Å; M126-A168 HydrophobicContact CG-CB 4.48Å
127	I	97.1	Very high	97.5	Very high	90 Å²	90	41.2 Å²	41.2	46%	0.462	21%	0.205	S	C	.	.	H	α-helix	trans	-65	-43.6	178.3	-68.1	166.5	0	0	0	110.9	T123 Q124 Q130 L131	T123-I127 HydrophobicContact CG2-CD1 4.03Å; T123-I127 WeakPolarHBondContact O-CG1 3.45Å; T123-I127 PolarHBondContact O-N 3.04Å; T123-I127 VanDerWaalsContact O-N 3.08Å; Q124-I127 PolarHBondContact O-N 3.17Å; I127-Q130 PolarHBondContact O-N 2.96Å; I127-L131 PolarHBondContact O-N 3.42Å
128	E	98.1	Very high	97.5	Very high	9 Å²	9	38.9 Å²	38.9	4%	0.042	20%	0.195	C	C	.	.	H	α-helix	trans	-70.1	-41.2	-178.5	-73.7	178.3	179.8	0	0	111.8	L22 F27 R30 Q124 L125 Q130 L131 V132 Y224	L22-E128 HydrophobicContact CD1-CB 4.18Å; L22-E128 HydrophobicContact CD1-CG 3.69Å; L22-E128 HydrophobicContact CD2-CB 3.87Å; L22-E128 HydrophobicContact CD2-CG 4.21Å; L22-E128 WeakPolarHBondContact CD2-O 3.4Å; F27-E128 HydrophobicContact CE1-CB 4.13Å; R30-E128 IonicContact CZ-OE1 3.18Å; R30-E128 IonicContact NE-OE1 3.59Å; R30-E128 PolarHBondContact NE-OE1 3.23Å; R30-E128 IonicContact NE-OE2 2.58Å; R30-E128 IonicContact NH2-OE1 3.87Å; R30-E128 PolarHBondContact NH2-OE1 3.48Å; Q124-E128 HydrophobicContact CG-CG 4.36Å; Q124-E128 WeakPolarHBondContact CG-OE1 3.22Å; Q124-E128 VanDerWaalsContact NE2-CD 3.33Å; Q124-E128 PolarHBondContact NE2-OE1 3.41Å; Q124-E128 WeakPolarHBondContact O-CB 3.1Å; Q124-E128 WeakPolarHBondContact O-CG 3.39Å; Q124-E128 PolarHBondContact O-N 2.99Å; L125-E128 PolarHBondContact O-N 3.26Å; E128-Q130 VanDerWaalsContact C-N 3.31Å; E128-Q130 PolarHBondContact O-N 2.98Å; E128-L131 WeakPolarHBondContact O-CB 3.12Å; E128-L131 PolarHBondContact O-N 2.96Å; E128-L131 VanDerWaalsContact O-N 3.17Å; E128-V132 PolarHBondContact O-N 2.84Å; E128-Y224 WeakPolarHBondContact OE2-CE1 3.26Å; E128-Y224 PolarHBondContact OE2-OH 3.13Å
129	A	97.8	Very high	97.4	Very high	1 Å²	1	40 Å²	40	1%	0.008	20%	0.201	C	C	.	.	H	α-helix	trans	-61	-40	172.9	0	0	0	0	0	111.9	L125 L131 V132 R133 I164 E165	L125-A129 VanDerWaalsContact O-CB 3.25Å; L125-A129 WeakPolarHBondContact O-CB 3.35Å; L125-A129 PolarHBondContact O-N 3.36Å; A129-L131 VanDerWaalsContact C-N 3.34Å; A129-L131 PolarHBondContact O-N 2.98Å; A129-V132 PolarHBondContact O-N 3.1Å; A129-R133 PolarHBondContact O-N 3.35Å; A129-I164 HydrophobicContact CB-CB 4.25Å; A129-I164 HydrophobicContact CB-CG2 3.85Å; A129-E165 HydrophobicContact CB-CG 4.16Å
130	Q	97.4	Very high	97.4	Very high	89 Å²	89	39.3 Å²	39.3	42%	0.416	20%	0.2	S	C	.	.	H	α-helix	trans	-63.7	-38	174.5	-179.9	165.8	92.3	0	0	112.6	M126 I127 E128 R133 L134 E165	M126-Q130 WeakPolarHBondContact O-CB 3.48Å; M126-Q130 PolarHBondContact O-N 2.88Å; M126-Q130 VanDerWaalsContact O-N 3.08Å; I127-Q130 PolarHBondContact O-N 2.96Å; E128-Q130 VanDerWaalsContact C-N 3.31Å; E128-Q130 PolarHBondContact O-N 2.98Å; Q130-R133 PolarHBondContact O-N 3.23Å; Q130-L134 PolarHBondContact O-N 3.42Å; Q130-E165 PolarHBondContact NE2-OE2 2.69Å
131	L	98	Very high	97.3	Very high	46 Å²	46	37.4 Å²	37.4	24%	0.241	19%	0.188	C	C	.	.	H	α-helix	trans	-64.7	-43.5	175.1	179.4	57.3	0	0	0	111.4	T15 D18 L22 I127 E128 A129 R133 L134 W135	T15-L131 HydrophobicContact CG2-CD1 3.83Å; D18-L131 HydrophobicContact CB-CD2 4.16Å; L22-L131 HydrophobicContact CD2-CB 4.24Å; L22-L131 HydrophobicContact CD2-CD2 4.05Å; L22-L131 HydrophobicContact CD2-CG 4.29Å; I127-L131 PolarHBondContact O-N 3.42Å; E128-L131 WeakPolarHBondContact O-CB 3.12Å; E128-L131 PolarHBondContact O-N 2.96Å; E128-L131 VanDerWaalsContact O-N 3.17Å; A129-L131 VanDerWaalsContact C-N 3.34Å; A129-L131 PolarHBondContact O-N 2.98Å; L131-R133 VanDerWaalsContact C-N 3.31Å; L131-R133 PolarHBondContact O-N 3.29Å; L131-L134 PolarHBondContact O-N 3.36Å; L131-W135 WeakPolarHBondContact O-CB 3.34Å; L131-W135 PolarHBondContact O-N 3.39Å
132	V	97.9	Very high	97.1	Very high	0 Å²	0	45.5 Å²	45.5	0%	0	22%	0.216	C	C	.	.	H	α-helix	trans	-58.6	-44.7	172.8	172.8	0	0	0	0	110.8	L22 V23 F27 E128 A129 L134 W135 V136 A161 L227 I231	L22-V132 HydrophobicContact CD2-CG2 3.84Å; V23-V132 HydrophobicContact CG1-CG2 3.62Å; F27-V132 HydrophobicContact CE2-CG2 4.05Å; F27-V132 HydrophobicContact CZ-CG2 3.63Å; E128-V132 PolarHBondContact O-N 2.84Å; A129-V132 PolarHBondContact O-N 3.1Å; V132-L134 PolarHBondContact O-N 3.36Å; V132-W135 HydrophobicContact CG1-CE3 4.31Å; V132-W135 WeakPolarHBondContact O-CB 3.34Å; V132-W135 PolarHBondContact O-N 3.42Å; V132-V136 HydrophobicContact CG1-CG2 4.3Å; V132-V136 WeakPolarHBondContact O-CG2 3.3Å; V132-V136 PolarHBondContact O-N 3.37Å; V132-A161 HydrophobicContact CG1-CB 4.45Å; V132-L227 HydrophobicContact CG1-CD2 4.36Å; V132-L227 HydrophobicContact CG2-CD2 4.4Å; V132-I231 HydrophobicContact CG1-CD1 3.67Å
133	R	97.4	Very high	97	Very high	57 Å²	57	53.1 Å²	53.1	22%	0.215	26%	0.255	C	S	.	.	H	α-helix	trans	-58.9	-46.3	178.3	-168.9	173.7	56.8	78.9	-3.4	111.8	A129 Q130 L131 Q137 L158 A161 E165	A129-R133 PolarHBondContact O-N 3.35Å; Q130-R133 PolarHBondContact O-N 3.23Å; L131-R133 VanDerWaalsContact C-N 3.31Å; L131-R133 PolarHBondContact O-N 3.29Å; R133-Q137 WeakPolarHBondContact O-CB 3.15Å; R133-Q137 VanDerWaalsContact O-CG 3.22Å; R133-Q137 WeakPolarHBondContact O-CG 3.1Å; R133-Q137 PolarHBondContact O-N 3.08Å; R133-L158 HydrophobicContact CB-CD2 4.32Å; R133-L158 HydrophobicContact CG-CD2 3.6Å; R133-L158 VanDerWaalsContact O-CD2 3.29Å; R133-L158 WeakPolarHBondContact O-CD2 3.06Å; R133-A161 HydrophobicContact CB-CB 4.37Å; R133-E165 WeakPolarHBondContact CD-OE1 3.47Å; R133-E165 IonicContact CZ-OE1 3.83Å; R133-E165 IonicContact NE-OE1 3.3Å; R133-E165 PolarHBondContact NE-OE1 3.32Å; R133-E165 IonicContact NE-OE2 2.65Å; R133-E165 IonicContact NH2-OE1 3.01Å; R133-E165 IonicContact NH2-OE2 2.89Å
134	L	97.6	Very high	96.7	Very high	39 Å²	39	53.8 Å²	53.8	20%	0.204	25%	0.254	C	S	.	.	H	α-helix	trans	-64.8	-41.4	176.6	-72.6	176.5	0	0	0	112.3	T15 Q130 L131 V132 Q137 F138	T15-L134 HydrophobicContact CG2-CB 3.97Å; Q130-L134 PolarHBondContact O-N 3.42Å; L131-L134 PolarHBondContact O-N 3.36Å; V132-L134 PolarHBondContact O-N 3.36Å; L134-Q137 PolarHBondContact O-N 3.2Å; L134-F138 HydrophobicContact CB-CE2 4.42Å; L134-F138 WeakPolarHBondContact O-CB 3.5Å; L134-F138 WeakPolarHBondContact O-CD2 3.43Å; L134-F138 VanDerWaalsContact O-CG 3.28Å; L134-F138 WeakPolarHBondContact O-CG 3.25Å; L134-F138 PolarHBondContact O-N 3Å
135	W	97.9	Very high	96.4	Very high	2 Å²	2	59 Å²	59	1%	0.008	28%	0.284	C	S	.	.	H	α-helix	trans	-58.7	-50.4	176.4	167.3	44.6	0	0	0	111.9	K16 E20 V23 L131 V132 F138 N139 I231 L235 I238	K16-W135 PolarHBondContact O-NE1 2.92Å; E20-W135 HydrophobicContact CB-CZ2 3.97Å; E20-W135 HydrophobicContact CG-CZ2 4.32Å; V23-W135 HydrophobicContact CB-CZ3 4.48Å; V23-W135 HydrophobicContact CG1-CE3 4.42Å; V23-W135 HydrophobicContact CG1-CZ3 3.92Å; V23-W135 HydrophobicContact CG2-CH2 3.83Å; V23-W135 HydrophobicContact CG2-CZ3 3.78Å; L131-W135 WeakPolarHBondContact O-CB 3.34Å; L131-W135 PolarHBondContact O-N 3.39Å; V132-W135 HydrophobicContact CG1-CE3 4.31Å; V132-W135 WeakPolarHBondContact O-CB 3.34Å; V132-W135 PolarHBondContact O-N 3.42Å; W135-F138 PolarHBondContact O-N 3Å; W135-N139 PolarHBondContact NE1-ND2 3.42Å; W135-N139 PolarHBondContact O-N 3.06Å; W135-N139 PolarHBondContact O-ND2 3.39Å; W135-I231 HydrophobicContact CH2-CG2 3.87Å; W135-I231 HydrophobicContact CZ3-CD1 4.32Å; W135-I231 HydrophobicContact CZ3-CG2 3.84Å; W135-L235 HydrophobicContact CH2-CD1 3.78Å; W135-L235 HydrophobicContact CZ2-CD1 4.06Å; W135-I238 HydrophobicContact CH2-CG2 4.09Å; W135-I238 HydrophobicContact CZ2-CG2 4.06Å
136	V	97.6	Very high	96	Very high	1 Å²	1	60.8 Å²	60.8	1%	0.006	30%	0.303	C	S	.	.	H	α-helix	trans	-64.5	-43.4	178.6	178.4	0	0	0	0	110.3	V132 F138 N139 I140 Q154 I157 L158 I238	V132-V136 HydrophobicContact CG1-CG2 4.3Å; V132-V136 WeakPolarHBondContact O-CG2 3.3Å; V132-V136 PolarHBondContact O-N 3.37Å; V136-F138 VanDerWaalsContact C-N 3.31Å; V136-F138 PolarHBondContact O-N 2.8Å; V136-N139 PolarHBondContact O-N 2.95Å; V136-I140 PolarHBondContact O-N 2.98Å; V136-Q154 HydrophobicContact CG1-CB 3.92Å; V136-Q154 HydrophobicContact CG1-CG 4.28Å; V136-I157 HydrophobicContact CG2-CG2 4.03Å; V136-L158 HydrophobicContact CB-CD2 3.73Å; V136-L158 HydrophobicContact CB-CG 4.15Å; V136-L158 HydrophobicContact CG1-CD1 4.25Å; V136-L158 HydrophobicContact CG1-CD2 3.85Å; V136-L158 HydrophobicContact CG1-CG 3.68Å; V136-I238 HydrophobicContact CG2-CG2 4.1Å
137	Q	97.3	Very high	95.8	Very high	77 Å²	77	61.5 Å²	61.5	36%	0.36	31%	0.308	S	S	.	.	H	α-helix	trans	-57.6	-39.6	175.8	-78.4	177.9	-14.3	0	0	113.1	R133 L134 N139 I140 L158	R133-Q137 WeakPolarHBondContact O-CB 3.15Å; R133-Q137 VanDerWaalsContact O-CG 3.22Å; R133-Q137 WeakPolarHBondContact O-CG 3.1Å; R133-Q137 PolarHBondContact O-N 3.08Å; L134-Q137 PolarHBondContact O-N 3.2Å; Q137-N139 PolarHBondContact O-N 3.15Å; Q137-I140 PolarHBondContact O-N 3.23Å; Q137-L158 HydrophobicContact CG-CD1 3.96Å; Q137-L158 HydrophobicContact CG-CD2 3.71Å
138	F	96.9	Very high	95.6	Very high	50 Å²	50	60.1 Å²	60.1	22%	0.219	30%	0.302	C	S	.	.	H	α-helix	trans	-73.6	-12	177.4	-67.1	-26.6	0	0	0	114.3	Y11 K12 T15 K16 L134 W135 V136	Y11-F138 HydrophobicContact CD1-CE2 4.37Å; Y11-F138 HydrophobicContact CD1-CZ 4.4Å; Y11-F138 HydrophobicContact CE1-CE2 4.04Å; Y11-F138 HydrophobicContact CE1-CZ 4.04Å; K12-F138 HydrophobicContact CB-CD2 4.13Å; K12-F138 HydrophobicContact CB-CE2 4.28Å; K12-F138 HydrophobicContact CB-CG 4.4Å; K12-F138 HydrophobicContact CD-CD1 4.31Å; K12-F138 HydrophobicContact CD-CE1 4.35Å; K12-F138 HydrophobicContact CG-CD1 4.03Å; K12-F138 HydrophobicContact CG-CD2 4.03Å; K12-F138 HydrophobicContact CG-CE1 3.88Å; K12-F138 HydrophobicContact CG-CE2 3.87Å; K12-F138 HydrophobicContact CG-CG 4.11Å; K12-F138 HydrophobicContact CG-CZ 3.81Å; T15-F138 HydrophobicContact CG2-CD2 3.75Å; T15-F138 HydrophobicContact CG2-CE2 3.71Å; K16-F138 VanDerWaalsContact CE-O 3.24Å; K16-F138 WeakPolarHBondContact CE-O 3.36Å; K16-F138 HydrophobicContact CG-CB 4.33Å; L134-F138 HydrophobicContact CB-CE2 4.42Å; L134-F138 WeakPolarHBondContact O-CB 3.5Å; L134-F138 WeakPolarHBondContact O-CD2 3.43Å; L134-F138 VanDerWaalsContact O-CG 3.28Å; L134-F138 WeakPolarHBondContact O-CG 3.25Å; L134-F138 PolarHBondContact O-N 3Å; W135-F138 PolarHBondContact O-N 3Å; V136-F138 VanDerWaalsContact C-N 3.31Å; V136-F138 PolarHBondContact O-N 2.8Å
139	N	96.4	Very high	95.5	Very high	27 Å²	27	66.9 Å²	66.9	14%	0.144	33%	0.331	C	S	.	.	H	α-helix	trans	-96.8	-4.7	171.6	-73.1	-78.6	0	0	0	113.4	W135 V136 Q137 P141 Q154 I238	W135-N139 PolarHBondContact NE1-ND2 3.42Å; W135-N139 PolarHBondContact O-N 3.06Å; W135-N139 PolarHBondContact O-ND2 3.39Å; V136-N139 PolarHBondContact O-N 2.95Å; Q137-N139 PolarHBondContact O-N 3.15Å; N139-P141 WeakPolarHBondContact O-CD 3.48Å; N139-Q154 VanDerWaalsContact C-NE2 3.35Å; N139-Q154 PolarHBondContact O-NE2 2.91Å; N139-I238 VanDerWaalsContact CB-O 3.23Å; N139-I238 WeakPolarHBondContact CB-O 3.48Å
140	I	96.2	Very high	95.4	Very high	62 Å²	62	66.9 Å²	66.9	32%	0.318	33%	0.331	S	S	.	.	P	Polyproline II helix	trans	-67.8	125	173.1	-67.6	179.1	0	0	0	109.3	V136 Q137 Q154 L158	V136-I140 PolarHBondContact O-N 2.98Å; Q137-I140 PolarHBondContact O-N 3.23Å; I140-Q154 HydrophobicContact CG1-CB 4.24Å; I140-L158 HydrophobicContact CD1-CD1 3.54Å
141	P	95.3	Very high	95.4	Very high	38 Å²	38	63.4 Å²	63.4	25%	0.247	32%	0.316	C	S	.	.	P	Polyproline II helix	trans	-78	173.8	-179.1	34.8	-37.9	0	0	0	111.3	N139 I143 V151 P241	N139-P141 WeakPolarHBondContact O-CD 3.48Å; P141-I143 PolarHBondContact O-N 3.38Å; P141-V151 HydrophobicContact CG-CG2 3.82Å; P141-P241 HydrophobicContact CG-CG 3.83Å
142	R	94.8	Very high	95.4	Very high	191 Å²	191	62.7 Å²	62.7	72%	0.721	32%	0.32	S	S	*	.	P	Polyproline II helix	trans	-55	136.5	170.7	-179.3	-174.3	65.1	-178.4	-2	110.5	E144 R242	R142-E144 IonicContact CZ-OE1 3.8Å; R142-E144 IonicContact NE-OE1 3.52Å; R142-E144 IonicContact NH2-OE1 2.8Å; R142-E144 PolarHBondContact NH2-OE1 3.16Å; R142-E144 PolarHBondContact O-N 2.97Å; R142-R242 PolarHBondContact O-NH1 3.43Å; R142-R242 PolarHBondContact O-NH2 3.12Å
143	I	93.7	Very high	95.3	Very high	160 Å²	160	63.6 Å²	63.6	82%	0.821	33%	0.325	S	S	*	.	P	Polyproline II helix	trans	-57.4	131.4	176	-58.8	172.7	0	0	0	110.5	P141	P141-I143 PolarHBondContact O-N 3.38Å
144	E	91.9	Very high	95.4	Very high	70 Å²	70	60.9 Å²	60.9	33%	0.327	31%	0.314	S	S	.	.			trans	-138.8	159.7	177.3	-69.3	176.2	-179.2	0	0	109.4	R142 G146 N148 R242	R142-E144 IonicContact CZ-OE1 3.8Å; R142-E144 IonicContact NE-OE1 3.52Å; R142-E144 IonicContact NH2-OE1 2.8Å; R142-E144 PolarHBondContact NH2-OE1 3.16Å; R142-E144 PolarHBondContact O-N 2.97Å; E144-G146 VanDerWaalsContact C-N 3.29Å; E144-G146 PolarHBondContact O-N 2.88Å; E144-N148 PolarHBondContact O-ND2 3.47Å; E144-N148 PolarHBondContact O-OD1 3.03Å; E144-R242 VanDerWaalsContact CD-CZ 3.49Å; E144-R242 IonicContact OE1-NH1 3.15Å; E144-R242 PolarHBondContact OE1-NH1 3.27Å; E144-R242 IonicContact OE2-CZ 2.73Å; E144-R242 IonicContact OE2-NE 2.76Å; E144-R242 PolarHBondContact OE2-NE 3.27Å; E144-R242 IonicContact OE2-NH1 3.44Å; E144-R242 PolarHBondContact OE2-NH1 3.01Å; E144-R242 IonicContact OE2-NH2 3.95Å
145	D	89.4	Confident	95.4	Very high	177 Å²	177	64.7 Å²	64.7	95%	0.947	33%	0.331	S	S	*	.	S	Bend	trans	-73	-20	-173	-157.2	34.4	0	0	0	113.4
146	G	91	Very high	95.4	Very high	40 Å²	40	70.7 Å²	70.7	41%	0.412	36%	0.359	S	S	.	.	S	Bend	trans	-142.5	178.5	-177.9	0	0	0	0	0	113.5	E144 N148	E144-G146 VanDerWaalsContact C-N 3.29Å; E144-G146 PolarHBondContact O-N 2.88Å; G146-N148 VanDerWaalsContact C-N 3.3Å; G146-N148 PolarHBondContact O-N 3.21Å; G146-N148 PolarHBondContact O-OD1 3.41Å
147	N	91.3	Very high	95.4	Very high	66 Å²	66	70.7 Å²	70.7	35%	0.353	36%	0.359	S	S	.	.			trans	58	39.8	-178.3	-165.4	21.8	0	0	0	113.3
148	N	94.6	Very high	95.4	Very high	61 Å²	61	68.2 Å²	68.2	33%	0.326	35%	0.348	S	S	.	.			trans	-98.3	8.4	-176.3	-64.5	-44.3	0	0	0	113.5	E144 G146 G150 V151 G152 R242	E144-N148 PolarHBondContact O-ND2 3.47Å; E144-N148 PolarHBondContact O-OD1 3.03Å; G146-N148 VanDerWaalsContact C-N 3.3Å; G146-N148 PolarHBondContact O-N 3.21Å; G146-N148 PolarHBondContact O-OD1 3.41Å; N148-G150 PolarHBondContact O-N 2.92Å; N148-V151 HydrophobicContact CB-CB 4.37Å; N148-V151 WeakPolarHBondContact O-CA 3.35Å; N148-V151 WeakPolarHBondContact O-CB 3.25Å; N148-V151 PolarHBondContact O-N 3.08Å; N148-V151 VanDerWaalsContact O-N 3.08Å; N148-G152 PolarHBondContact O-N 2.82Å; N148-R242 PolarHBondContact OD1-NH2 3.03Å
149	F	94.8	Very high	95.4	Very high	151 Å²	151	67.7 Å²	67.7	66%	0.662	36%	0.357	S	S	*	.	H	α-helix	trans	-57.9	-48.6	179	176.2	-99.3	0	0	0	112.2	V151 G152 I153	F149-V151 VanDerWaalsContact C-N 3.25Å; F149-V151 PolarHBondContact O-N 3.39Å; F149-G152 PolarHBondContact O-N 3.46Å; F149-I153 HydrophobicContact CD1-CD1 4.06Å; F149-I153 HydrophobicContact CE1-CD1 3.44Å; F149-I153 VanDerWaalsContact CE1-CD1 3.44Å; F149-I153 HydrophobicContact CE1-CG1 4.38Å; F149-I153 HydrophobicContact CZ-CD1 3.83Å; F149-I153 HydrophobicContact CZ-CG1 4.46Å; F149-I153 PolarHBondContact O-N 3.39Å
150	G	95.8	Very high	95.5	Very high	1 Å²	1	70 Å²	70	1%	0.01	37%	0.367	C	S	.	.	H	α-helix	trans	-65.8	-28.3	175.9	0	0	0	0	0	113.3	N148 I153 Q154 P241	N148-G150 PolarHBondContact O-N 2.92Å; G150-I153 PolarHBondContact O-N 3.34Å; G150-Q154 WeakPolarHBondContact O-CG 3.42Å; G150-Q154 PolarHBondContact O-N 3Å; G150-Q154 VanDerWaalsContact O-N 3.1Å; G150-P241 VanDerWaalsContact C-CB 3.46Å; G150-P241 WeakPolarHBondContact CA-O 3.24Å
151	V	97.1	Very high	95.6	Very high	15 Å²	15	67 Å²	67	9%	0.091	35%	0.352	C	S	.	.	H	α-helix	trans	-68.4	-40.6	173.6	-176.9	0	0	0	0	110.4	P141 N148 F149 I153 Q154 E155 P241	P141-V151 HydrophobicContact CG-CG2 3.82Å; N148-V151 HydrophobicContact CB-CB 4.37Å; N148-V151 WeakPolarHBondContact O-CA 3.35Å; N148-V151 WeakPolarHBondContact O-CB 3.25Å; N148-V151 PolarHBondContact O-N 3.08Å; N148-V151 VanDerWaalsContact O-N 3.08Å; F149-V151 VanDerWaalsContact C-N 3.25Å; F149-V151 PolarHBondContact O-N 3.39Å; V151-I153 VanDerWaalsContact C-N 3.3Å; V151-I153 PolarHBondContact O-N 2.85Å; V151-Q154 WeakPolarHBondContact O-CA 3.28Å; V151-Q154 WeakPolarHBondContact O-CB 3.39Å; V151-Q154 PolarHBondContact O-N 3.4Å; V151-Q154 VanDerWaalsContact O-N 3.09Å; V151-E155 WeakPolarHBondContact O-CG 3.44Å; V151-E155 PolarHBondContact O-N 3.39Å; V151-P241 HydrophobicContact CG2-CB 4.27Å
152	G	97.4	Very high	95.7	Very high	32 Å²	32	66.9 Å²	66.9	33%	0.33	35%	0.351	S	S	.	.	H	α-helix	trans	-59.8	-38.5	173.5	0	0	0	0	0	113.1	N148 F149 E155 E156	N148-G152 PolarHBondContact O-N 2.82Å; F149-G152 PolarHBondContact O-N 3.46Å; G152-E155 PolarHBondContact O-N 2.95Å; G152-E156 PolarHBondContact O-N 3.41Å
153	I	97.3	Very high	95.8	Very high	19 Å²	19	58.3 Å²	58.3	10%	0.097	32%	0.323	C	S	.	.	H	α-helix	trans	-63.3	-43	172.8	-67.6	172.6	0	0	0	111.1	F149 G150 V151 E155 E156 I157 N234 R237	F149-I153 HydrophobicContact CD1-CD1 4.06Å; F149-I153 HydrophobicContact CE1-CD1 3.44Å; F149-I153 VanDerWaalsContact CE1-CD1 3.44Å; F149-I153 HydrophobicContact CE1-CG1 4.38Å; F149-I153 HydrophobicContact CZ-CD1 3.83Å; F149-I153 HydrophobicContact CZ-CG1 4.46Å; F149-I153 PolarHBondContact O-N 3.39Å; G150-I153 PolarHBondContact O-N 3.34Å; V151-I153 VanDerWaalsContact C-N 3.3Å; V151-I153 PolarHBondContact O-N 2.85Å; I153-E155 VanDerWaalsContact C-N 3.32Å; I153-E155 PolarHBondContact O-N 3.44Å; I153-E156 PolarHBondContact O-N 3.16Å; I153-I157 HydrophobicContact CG2-CD1 4.1Å; I153-I157 WeakPolarHBondContact O-CG1 3.45Å; I153-I157 PolarHBondContact O-N 3.01Å; I153-I157 VanDerWaalsContact O-N 3.16Å; I153-N234 HydrophobicContact CG2-CB 3.74Å; I153-R237 HydrophobicContact CD1-CB 4.03Å; I153-R237 HydrophobicContact CD1-CG 3.92Å; I153-R237 HydrophobicContact CG2-CB 4.26Å
154	Q	97.9	Very high	96	Very high	0 Å²	0	50.8 Å²	50.8	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-60.2	-43.1	174.9	-69.8	173.3	-38.7	0	0	111.2	V136 N139 I140 G150 V151 I157 L158 I238	V136-Q154 HydrophobicContact CG1-CB 3.92Å; V136-Q154 HydrophobicContact CG1-CG 4.28Å; N139-Q154 VanDerWaalsContact C-NE2 3.35Å; N139-Q154 PolarHBondContact O-NE2 2.91Å; I140-Q154 HydrophobicContact CG1-CB 4.24Å; G150-Q154 WeakPolarHBondContact O-CG 3.42Å; G150-Q154 PolarHBondContact O-N 3Å; G150-Q154 VanDerWaalsContact O-N 3.1Å; V151-Q154 WeakPolarHBondContact O-CA 3.28Å; V151-Q154 WeakPolarHBondContact O-CB 3.39Å; V151-Q154 PolarHBondContact O-N 3.4Å; V151-Q154 VanDerWaalsContact O-N 3.09Å; Q154-I157 PolarHBondContact O-N 3.17Å; Q154-L158 VanDerWaalsContact O-CG 3.28Å; Q154-L158 WeakPolarHBondContact O-CG 3.38Å; Q154-L158 PolarHBondContact O-N 2.93Å; Q154-I238 PolarHBondContact NE2-O 3.25Å
155	E	97.7	Very high	96.2	Very high	118 Å²	118	48.7 Å²	48.7	55%	0.551	28%	0.275	S	S	*	.	H	α-helix	trans	-62.6	-39	177.5	-71.4	175.4	171.1	0	0	112.8	V151 G152 I153 L158 G159	V151-E155 WeakPolarHBondContact O-CG 3.44Å; V151-E155 PolarHBondContact O-N 3.39Å; G152-E155 PolarHBondContact O-N 2.95Å; I153-E155 VanDerWaalsContact C-N 3.32Å; I153-E155 PolarHBondContact O-N 3.44Å; E155-L158 WeakPolarHBondContact O-CB 3.26Å; E155-L158 PolarHBondContact O-N 3.04Å; E155-G159 PolarHBondContact O-N 3.29Å
156	E	97.9	Very high	96.5	Very high	129 Å²	129	47.2 Å²	47.2	60%	0.603	26%	0.256	S	S	*	.	H	α-helix	trans	-63.2	-46.5	176.1	-173.9	174	175.9	0	0	111.8	G152 I153 L158 G159 E160	G152-E156 PolarHBondContact O-N 3.41Å; I153-E156 PolarHBondContact O-N 3.16Å; E156-L158 VanDerWaalsContact C-N 3.31Å; E156-L158 PolarHBondContact O-N 3.01Å; E156-G159 WeakPolarHBondContact O-CA 3.4Å; E156-G159 PolarHBondContact O-N 2.9Å; E156-E160 PolarHBondContact O-N 2.96Å
157	I	97.5	Very high	96.8	Very high	1 Å²	1	48.4 Å²	48.4	1%	0.005	25%	0.252	C	S	.	.	H	α-helix	trans	-65	-36.9	177.6	-65.4	170.4	0	0	0	111.1	V136 I153 Q154 G159 E160 A161 I230 I231 N234 I238	V136-I157 HydrophobicContact CG2-CG2 4.03Å; I153-I157 HydrophobicContact CG2-CD1 4.1Å; I153-I157 WeakPolarHBondContact O-CG1 3.45Å; I153-I157 PolarHBondContact O-N 3.01Å; I153-I157 VanDerWaalsContact O-N 3.16Å; Q154-I157 PolarHBondContact O-N 3.17Å; I157-G159 VanDerWaalsContact C-N 3.31Å; I157-E160 PolarHBondContact O-N 3.14Å; I157-A161 PolarHBondContact O-N 3.03Å; I157-I230 HydrophobicContact CG1-CD1 4.34Å; I157-I230 HydrophobicContact CG1-CG1 4.37Å; I157-I231 HydrophobicContact CG2-CD1 4.2Å; I157-I231 HydrophobicContact CG2-CG1 3.86Å; I157-N234 HydrophobicContact CD1-CB 4.17Å; I157-I238 HydrophobicContact CD1-CD1 3.35Å; I157-I238 HydrophobicContact CD1-CG1 3.49Å; I157-I238 VanDerWaalsContact CD1-CG1 3.49Å
158	L	98	Very high	97.1	Very high	24 Å²	24	45.3 Å²	45.3	13%	0.126	24%	0.236	C	C	.	.	H	α-helix	trans	-62.8	-39.1	171.7	-73.7	175.7	0	0	0	112.2	R133 V136 Q137 I140 Q154 E155 E156 S162	R133-L158 HydrophobicContact CB-CD2 4.32Å; R133-L158 HydrophobicContact CG-CD2 3.6Å; R133-L158 VanDerWaalsContact O-CD2 3.29Å; R133-L158 WeakPolarHBondContact O-CD2 3.06Å; V136-L158 HydrophobicContact CB-CD2 3.73Å; V136-L158 HydrophobicContact CB-CG 4.15Å; V136-L158 HydrophobicContact CG1-CD1 4.25Å; V136-L158 HydrophobicContact CG1-CD2 3.85Å; V136-L158 HydrophobicContact CG1-CG 3.68Å; Q137-L158 HydrophobicContact CG-CD1 3.96Å; Q137-L158 HydrophobicContact CG-CD2 3.71Å; I140-L158 HydrophobicContact CD1-CD1 3.54Å; Q154-L158 VanDerWaalsContact O-CG 3.28Å; Q154-L158 WeakPolarHBondContact O-CG 3.38Å; Q154-L158 PolarHBondContact O-N 2.93Å; E155-L158 WeakPolarHBondContact O-CB 3.26Å; E155-L158 PolarHBondContact O-N 3.04Å; E156-L158 VanDerWaalsContact C-N 3.31Å; E156-L158 PolarHBondContact O-N 3.01Å; L158-S162 VanDerWaalsContact O-CB 3.25Å; L158-S162 WeakPolarHBondContact O-CB 3.49Å; L158-S162 PolarHBondContact O-N 3.35Å
159	G	98	Very high	97.1	Very high	39 Å²	39	45.3 Å²	45.3	40%	0.402	24%	0.241	S	C	.	.	H	α-helix	trans	-59.4	-46.9	174.6	0	0	0	0	0	112.1	E155 E156 I157 S162 G163	E155-G159 PolarHBondContact O-N 3.29Å; E156-G159 WeakPolarHBondContact O-CA 3.4Å; E156-G159 PolarHBondContact O-N 2.9Å; I157-G159 VanDerWaalsContact C-N 3.31Å; G159-S162 PolarHBondContact O-N 3.4Å; G159-G163 PolarHBondContact O-N 2.84Å
160	E	97.6	Very high	97.2	Very high	75 Å²	75	41.3 Å²	41.3	35%	0.35	23%	0.228	S	C	.	.	H	α-helix	trans	-62.2	-51.9	177.5	-175.1	67.8	-175.2	0	0	111.6	E156 I157 S162 G163 I164 L227	E156-E160 PolarHBondContact O-N 2.96Å; I157-E160 PolarHBondContact O-N 3.14Å; E160-S162 VanDerWaalsContact C-N 3.27Å; E160-S162 PolarHBondContact O-N 3.4Å; E160-G163 WeakPolarHBondContact O-CA 3.36Å; E160-G163 PolarHBondContact O-N 3.38Å; E160-I164 HydrophobicContact CG-CD1 4.45Å; E160-I164 WeakPolarHBondContact O-CG1 3.4Å; E160-I164 PolarHBondContact O-N 3.03Å; E160-L227 HydrophobicContact CB-CD1 4.45Å; E160-L227 HydrophobicContact CG-CD1 4.01Å
161	A	97.8	Very high	97.2	Very high	0 Å²	0	42 Å²	42	0%	0	23%	0.231	C	C	.	.	H	α-helix	trans	-59.2	-38.8	177.9	0	0	0	0	0	112.1	V132 R133 I157 I164 E165	V132-A161 HydrophobicContact CG1-CB 4.45Å; R133-A161 HydrophobicContact CB-CB 4.37Å; I157-A161 PolarHBondContact O-N 3.03Å; A161-I164 PolarHBondContact O-N 3.23Å; A161-E165 PolarHBondContact O-N 3.22Å
162	S	97.6	Very high	97.1	Very high	35 Å²	35	43.5 Å²	43.5	25%	0.245	24%	0.238	C	C	.	.	H	α-helix	trans	-68.8	-33.4	174.8	-176.7	0	0	0	0	112.8	L158 G159 E160 E165 R166	L158-S162 VanDerWaalsContact O-CB 3.25Å; L158-S162 WeakPolarHBondContact O-CB 3.49Å; L158-S162 PolarHBondContact O-N 3.35Å; G159-S162 PolarHBondContact O-N 3.4Å; E160-S162 VanDerWaalsContact C-N 3.27Å; E160-S162 PolarHBondContact O-N 3.4Å; S162-E165 PolarHBondContact O-N 3.39Å; S162-R166 WeakPolarHBondContact O-CG 3.44Å; S162-R166 PolarHBondContact O-N 3.47Å; S162-R166 PolarHBondContact OG-NH1 3.46Å
163	G	97.8	Very high	97.1	Very high	12 Å²	12	46.4 Å²	46.4	12%	0.124	25%	0.246	C	C	.	.	H	α-helix	trans	-59.2	-48.7	171.8	0	0	0	0	0	111.6	G159 E160 E165 R166 D167	G159-G163 PolarHBondContact O-N 2.84Å; E160-G163 WeakPolarHBondContact O-CA 3.36Å; E160-G163 PolarHBondContact O-N 3.38Å; G163-E165 VanDerWaalsContact C-N 3.33Å; G163-E165 PolarHBondContact O-N 3.02Å; G163-R166 WeakPolarHBondContact O-CB 3.46Å; G163-R166 PolarHBondContact O-N 3.31Å; G163-D167 PolarHBondContact O-N 2.94Å
164	I	98	Very high	96.9	Very high	2 Å²	2	48.1 Å²	48.1	1%	0.01	25%	0.254	C	S	.	.	H	α-helix	trans	-57.8	-43.4	177.7	-65.5	166.6	0	0	0	111.7	L125 A129 E160 A161 R166 D167 A168 H223 L227	L125-I164 HydrophobicContact CD1-CG2 3.83Å; L125-I164 HydrophobicContact CD2-CG2 3.81Å; L125-I164 HydrophobicContact CG-CG2 3.66Å; A129-I164 HydrophobicContact CB-CB 4.25Å; A129-I164 HydrophobicContact CB-CG2 3.85Å; E160-I164 HydrophobicContact CG-CD1 4.45Å; E160-I164 WeakPolarHBondContact O-CG1 3.4Å; E160-I164 PolarHBondContact O-N 3.03Å; A161-I164 PolarHBondContact O-N 3.23Å; I164-R166 VanDerWaalsContact C-N 3.32Å; I164-R166 PolarHBondContact O-N 3.19Å; I164-D167 PolarHBondContact O-N 3.23Å; I164-A168 WeakPolarHBondContact O-CB 3.44Å; I164-A168 PolarHBondContact O-N 3.41Å; I164-H223 HydrophobicContact CD1-CB 3.99Å; I164-H223 HydrophobicContact CG1-CB 4.04Å; I164-H223 HydrophobicContact CG2-CB 4.31Å; I164-L227 HydrophobicContact CD1-CB 4.06Å; I164-L227 HydrophobicContact CD1-CD1 4.43Å; I164-L227 HydrophobicContact CD1-CD2 3.78Å; I164-L227 HydrophobicContact CD1-CG 4.31Å
165	E	95.7	Very high	96.8	Very high	26 Å²	26	48.3 Å²	48.3	12%	0.121	26%	0.255	C	S	.	.	H	α-helix	trans	-59.5	-40.8	175.6	-73.3	179.1	-87	0	0	111.9	A129 Q130 R133 A161 S162 G163 C169	A129-E165 HydrophobicContact CB-CG 4.16Å; Q130-E165 PolarHBondContact NE2-OE2 2.69Å; R133-E165 WeakPolarHBondContact CD-OE1 3.47Å; R133-E165 IonicContact CZ-OE1 3.83Å; R133-E165 IonicContact NE-OE1 3.3Å; R133-E165 PolarHBondContact NE-OE1 3.32Å; R133-E165 IonicContact NE-OE2 2.65Å; R133-E165 IonicContact NH2-OE1 3.01Å; R133-E165 IonicContact NH2-OE2 2.89Å; A161-E165 PolarHBondContact O-N 3.22Å; S162-E165 PolarHBondContact O-N 3.39Å; G163-E165 VanDerWaalsContact C-N 3.33Å; G163-E165 PolarHBondContact O-N 3.02Å; E165-C169 PolarHBondContact O-N 3.29Å; E165-C169 VanDerWaalsContact O-N 3.14Å; E165-C169 PolarHBondContact O-SG 2.99Å
166	R	96.6	Very high	96.6	Very high	145 Å²	145	47 Å²	47	55%	0.547	26%	0.255	S	S	.	.	H	α-helix	trans	-69.5	-41.8	178.6	-69.7	-174.4	-64.3	-100.9	2.2	112.5	S162 G163 I164 A168 C169 T170	S162-R166 WeakPolarHBondContact O-CG 3.44Å; S162-R166 PolarHBondContact O-N 3.47Å; S162-R166 PolarHBondContact OG-NH1 3.46Å; G163-R166 WeakPolarHBondContact O-CB 3.46Å; G163-R166 PolarHBondContact O-N 3.31Å; I164-R166 VanDerWaalsContact C-N 3.32Å; I164-R166 PolarHBondContact O-N 3.19Å; R166-A168 VanDerWaalsContact C-N 3.33Å; R166-C169 PolarHBondContact O-N 2.99Å; R166-T170 PolarHBondContact O-N 3.25Å; R166-T170 PolarHBondContact O-OG1 3.45Å
167	D	97.3	Very high	96.6	Very high	65 Å²	65	46.7 Å²	46.7	35%	0.348	25%	0.248	S	C	.	.	H	α-helix	trans	-64.1	-43.2	177.7	-68	-17.4	0	0	0	110	G163 I164 C169 T170 F171 H223	G163-D167 PolarHBondContact O-N 2.94Å; I164-D167 PolarHBondContact O-N 3.23Å; D167-C169 PolarHBondContact O-N 3.14Å; D167-T170 WeakPolarHBondContact O-CB 3.43Å; D167-T170 PolarHBondContact O-N 3.44Å; D167-T170 VanDerWaalsContact O-N 3.12Å; D167-F171 HydrophobicContact CB-CE2 4.05Å; D167-F171 WeakPolarHBondContact O-CD2 3.32Å; D167-F171 VanDerWaalsContact O-CG 3.28Å; D167-F171 WeakPolarHBondContact O-CG 3.47Å; D167-F171 PolarHBondContact O-N 3.27Å; D167-H223 IonicContact OD2-CE1 3.45Å; D167-H223 IonicContact OD2-NE2 2.83Å
168	A	96.2	Very high	96.6	Very high	1 Å²	1	47 Å²	47	1%	0.008	25%	0.25	C	C	.	.	H	α-helix	trans	-59.6	-43.9	176.2	0	0	0	0	0	113	L122 M126 I164 R166 T170 F171 L172	L122-A168 HydrophobicContact CD1-CB 3.85Å; L122-A168 HydrophobicContact CG-CB 4.23Å; M126-A168 HydrophobicContact CB-CB 4.06Å; M126-A168 HydrophobicContact CG-CB 4.48Å; I164-A168 WeakPolarHBondContact O-CB 3.44Å; I164-A168 PolarHBondContact O-N 3.41Å; R166-A168 VanDerWaalsContact C-N 3.33Å; A168-T170 VanDerWaalsContact C-N 3.34Å; A168-T170 PolarHBondContact O-N 3.2Å; A168-F171 PolarHBondContact O-N 2.91Å; A168-L172 WeakPolarHBondContact O-CG 3.45Å; A168-L172 PolarHBondContact O-N 2.92Å
169	C	94.9	Very high	96.5	Very high	62 Å²	62	49.7 Å²	49.7	42%	0.419	26%	0.259	S	S	.	.	H	α-helix	trans	-60.7	-44	174.2	-68.2	0	0	0	0	111.6	E165 R166 D167 F171 L172 D173	E165-C169 PolarHBondContact O-N 3.29Å; E165-C169 VanDerWaalsContact O-N 3.14Å; E165-C169 PolarHBondContact O-SG 2.99Å; R166-C169 PolarHBondContact O-N 2.99Å; D167-C169 PolarHBondContact O-N 3.14Å; C169-F171 VanDerWaalsContact C-N 3.35Å; C169-F171 PolarHBondContact O-N 3.48Å; C169-L172 PolarHBondContact O-N 2.98Å; C169-D173 PolarHBondContact O-N 3.47Å; C169-D173 VanDerWaalsContact O-N 3.11Å
170	T	96.9	Very high	96.4	Very high	66 Å²	66	50.4 Å²	50.4	41%	0.405	26%	0.261	S	S	.	.	H	α-helix	trans	-62	-42.7	179.3	-60.2	0	0	0	0	111.6	R166 D167 A168 D173 Q174	R166-T170 PolarHBondContact O-N 3.25Å; R166-T170 PolarHBondContact O-OG1 3.45Å; D167-T170 WeakPolarHBondContact O-CB 3.43Å; D167-T170 PolarHBondContact O-N 3.44Å; D167-T170 VanDerWaalsContact O-N 3.12Å; A168-T170 VanDerWaalsContact C-N 3.34Å; A168-T170 PolarHBondContact O-N 3.2Å; T170-D173 PolarHBondContact O-N 3.3Å; T170-Q174 WeakPolarHBondContact O-CG 3.36Å; T170-Q174 PolarHBondContact O-N 3.07Å
171	F	97.1	Very high	96.4	Very high	16 Å²	16	49.4 Å²	49.4	7%	0.07	26%	0.262	C	S	.	.	H	α-helix	trans	-66.4	-39.7	176.6	-65.3	-35.1	0	0	0	112.3	L122 D167 A168 C169 D173 Q174 V175 Y215 I216 E219	L122-F171 HydrophobicContact CD1-CB 4.22Å; L122-F171 HydrophobicContact CD1-CD2 3.99Å; L122-F171 HydrophobicContact CD2-CB 3.53Å; D167-F171 HydrophobicContact CB-CE2 4.05Å; D167-F171 WeakPolarHBondContact O-CD2 3.32Å; D167-F171 VanDerWaalsContact O-CG 3.28Å; D167-F171 WeakPolarHBondContact O-CG 3.47Å; D167-F171 PolarHBondContact O-N 3.27Å; A168-F171 PolarHBondContact O-N 2.91Å; C169-F171 VanDerWaalsContact C-N 3.35Å; C169-F171 PolarHBondContact O-N 3.48Å; F171-D173 VanDerWaalsContact C-N 3.31Å; F171-D173 PolarHBondContact O-N 3.03Å; F171-Q174 WeakPolarHBondContact O-CB 3.41Å; F171-Q174 PolarHBondContact O-N 3.35Å; F171-V175 PolarHBondContact O-N 2.94Å; F171-Y215 HydrophobicContact CE1-CE1 4.21Å; F171-Y215 HydrophobicContact CZ-CE1 4.31Å; F171-I216 HydrophobicContact CB-CD1 3.85Å; F171-I216 HydrophobicContact CB-CG1 4.17Å; F171-I216 HydrophobicContact CB-CG2 4.39Å; F171-I216 HydrophobicContact CD1-CD1 3.87Å; F171-I216 HydrophobicContact CD1-CG1 3.69Å; F171-I216 HydrophobicContact CD2-CG1 4.24Å; F171-I216 HydrophobicContact CD2-CG2 4.27Å; F171-I216 HydrophobicContact CE1-CG1 4.11Å; F171-I216 HydrophobicContact CG-CD1 3.95Å; F171-I216 HydrophobicContact CG-CG1 3.78Å; F171-I216 HydrophobicContact CG-CG2 4.35Å; F171-E219 HydrophobicContact CE2-CB 4.09Å; F171-E219 HydrophobicContact CE2-CG 4.5Å; F171-E219 HydrophobicContact CZ-CB 4.25Å; F171-E219 HydrophobicContact CZ-CG 4.16Å
172	L	95.1	Very high	96.3	Very high	46 Å²	46	50 Å²	50	24%	0.241	26%	0.264	C	S	.	.	H	α-helix	trans	-59.6	-41.8	174.5	-75.6	171.2	0	0	0	111.8	L122 A168 C169 Q174 V175	L122-L172 HydrophobicContact CD2-CB 4.48Å; L122-L172 HydrophobicContact CD2-CD2 3.79Å; L122-L172 HydrophobicContact CD2-CG 3.65Å; L122-L172 HydrophobicContact CG-CD2 4.44Å; L122-L172 HydrophobicContact CG-CG 4.28Å; A168-L172 WeakPolarHBondContact O-CG 3.45Å; A168-L172 PolarHBondContact O-N 2.92Å; C169-L172 PolarHBondContact O-N 2.98Å; L172-Q174 VanDerWaalsContact C-N 3.34Å; L172-Q174 PolarHBondContact O-N 3.35Å; L172-V175 PolarHBondContact O-N 3.27Å
173	D	95.3	Very high	96.2	Very high	93 Å²	93	50.5 Å²	50.5	50%	0.497	28%	0.275	S	S	.	.	H	α-helix	trans	-65.3	-36.1	177	-76.8	-16.8	0	0	0	112.9	C169 T170 F171 V175 T176 R177	C169-D173 PolarHBondContact O-N 3.47Å; C169-D173 VanDerWaalsContact O-N 3.11Å; T170-D173 PolarHBondContact O-N 3.3Å; F171-D173 VanDerWaalsContact C-N 3.31Å; F171-D173 PolarHBondContact O-N 3.03Å; D173-V175 PolarHBondContact O-N 3.24Å; D173-T176 PolarHBondContact O-N 2.91Å; D173-R177 WeakPolarHBondContact O-CG 3.44Å; D173-R177 PolarHBondContact O-N 3.28Å
174	Q	95	Very high	96.1	Very high	56 Å²	56	57.5 Å²	57.5	26%	0.262	30%	0.302	S	S	.	.	H	α-helix	trans	-58.6	-38	177	-70.9	178.9	18.7	0	0	111.3	T170 F171 L172 T176 R177 Y178	T170-Q174 WeakPolarHBondContact O-CG 3.36Å; T170-Q174 PolarHBondContact O-N 3.07Å; F171-Q174 WeakPolarHBondContact O-CB 3.41Å; F171-Q174 PolarHBondContact O-N 3.35Å; L172-Q174 VanDerWaalsContact C-N 3.34Å; L172-Q174 PolarHBondContact O-N 3.35Å; Q174-T176 PolarHBondContact O-N 3.01Å; Q174-R177 PolarHBondContact O-N 3.48Å; Q174-Y178 PolarHBondContact O-N 2.88Å
175	V	95	Very high	95.9	Very high	3 Å²	3	58.8 Å²	58.8	2%	0.018	31%	0.309	C	S	.	.	H	α-helix	trans	-63.8	-42.4	179.3	-178.2	0	0	0	0	111.9	I115 F171 L172 D173 Y178 Y179 M213	I115-V175 HydrophobicContact CB-CG1 4.32Å; I115-V175 HydrophobicContact CD1-CG1 3.86Å; I115-V175 HydrophobicContact CG1-CG1 3.87Å; I115-V175 HydrophobicContact CG2-CG1 3.5Å; I115-V175 VanDerWaalsContact CG2-CG1 3.5Å; F171-V175 PolarHBondContact O-N 2.94Å; L172-V175 PolarHBondContact O-N 3.27Å; D173-V175 PolarHBondContact O-N 3.24Å; V175-Y178 PolarHBondContact O-N 3.39Å; V175-Y179 HydrophobicContact CG1-CE2 4.12Å; V175-Y179 VanDerWaalsContact O-CD2 3.3Å; V175-Y179 WeakPolarHBondContact O-CD2 3.45Å; V175-M213 HydrophobicContact CG2-CE 4.11Å; V175-M213 HydrophobicContact CG2-SD 4.49Å
176	T	94.5	Very high	95.8	Very high	90 Å²	90	58.6 Å²	58.6	55%	0.552	31%	0.31	S	S	*	.	H	α-helix	trans	-67.7	-39.4	176.6	-58	0	0	0	0	111.3	D173 Q174 Y178 Y179 A180	D173-T176 PolarHBondContact O-N 2.91Å; Q174-T176 PolarHBondContact O-N 3.01Å; T176-Y178 VanDerWaalsContact C-N 3.28Å; T176-Y178 PolarHBondContact O-N 2.99Å; T176-Y179 PolarHBondContact O-N 2.99Å; T176-A180 PolarHBondContact O-N 2.58Å
177	R	96.7	Very high	95.5	Very high	123 Å²	123	53.1 Å²	53.1	46%	0.464	30%	0.298	S	S	.	.	H	α-helix	trans	-61.7	-33	176.9	-76.8	-170	-71.2	-95.4	-1	113.2	D173 Q174 S181	D173-R177 WeakPolarHBondContact O-CG 3.44Å; D173-R177 PolarHBondContact O-N 3.28Å; Q174-R177 PolarHBondContact O-N 3.48Å; R177-S181 VanDerWaalsContact O-CB 3.26Å; R177-S181 WeakPolarHBondContact O-CB 3.39Å; R177-S181 PolarHBondContact O-N 3.44Å; R177-S181 PolarHBondContact O-OG 3.47Å
178	Y	97.3	Very high	95.3	Very high	9 Å²	9	54.1 Å²	54.1	4%	0.035	30%	0.299	C	S	.	.	H	α-helix	trans	-59.1	-54.3	174.5	167.8	-106.5	0	0	0	111.4	I111 I115 Q174 V175 T176 A180 S181 R182 M205 D206 Q209	I111-Y178 HydrophobicContact CB-CE1 4.35Å; I111-Y178 HydrophobicContact CG2-CD1 4.13Å; I111-Y178 HydrophobicContact CG2-CE1 3.42Å; I111-Y178 VanDerWaalsContact CG2-CE1 3.42Å; I111-Y178 HydrophobicContact CG2-CE2 4.35Å; I115-Y178 HydrophobicContact CD1-CD1 3.99Å; I115-Y178 HydrophobicContact CD1-CE1 4.31Å; Q174-Y178 PolarHBondContact O-N 2.88Å; V175-Y178 PolarHBondContact O-N 3.39Å; T176-Y178 VanDerWaalsContact C-N 3.28Å; T176-Y178 PolarHBondContact O-N 2.99Å; Y178-A180 VanDerWaalsContact C-N 3.32Å; Y178-A180 PolarHBondContact O-N 3.28Å; Y178-S181 PolarHBondContact O-N 3.2Å; Y178-R182 VanDerWaalsContact O-CB 3.31Å; Y178-R182 WeakPolarHBondContact O-CB 3.2Å; Y178-R182 PolarHBondContact O-N 3.41Å; Y178-R182 WeakPolarHBondContact OH-CD 3.28Å; Y178-R182 PolarHBondContact OH-NE 2.89Å; Y178-M205 HydrophobicContact CD2-CG 4.32Å; Y178-M205 HydrophobicContact CE2-CE 4.24Å; Y178-M205 HydrophobicContact CE2-CG 4.34Å; Y178-D206 WeakPolarHBondContact CE2-OD1 3.47Å; Y178-D206 PolarHBondContact OH-OD1 2.86Å; Y178-Q209 HydrophobicContact CD1-CG 4.08Å; Y178-Q209 HydrophobicContact CD2-CB 3.6Å; Y178-Q209 HydrophobicContact CD2-CG 3.48Å; Y178-Q209 VanDerWaalsContact CD2-CG 3.48Å; Y178-Q209 HydrophobicContact CE1-CG 4.3Å; Y178-Q209 HydrophobicContact CE2-CB 3.59Å; Y178-Q209 HydrophobicContact CE2-CG 3.73Å; Y178-Q209 HydrophobicContact CG-CB 4.31Å; Y178-Q209 HydrophobicContact CG-CG 3.66Å
179	Y	96.3	Very high	95.1	Very high	79 Å²	79	54.1 Å²	54.1	31%	0.31	30%	0.299	S	S	.	.	H	α-helix	trans	-60.3	-42.3	179.8	-68.8	-68.4	0	0	0	112.3	I115 V175 T176 G183	I115-Y179 HydrophobicContact CD1-CE2 3.8Å; I115-Y179 WeakPolarHBondContact CD1-OH 3.4Å; V175-Y179 HydrophobicContact CG1-CE2 4.12Å; V175-Y179 VanDerWaalsContact O-CD2 3.3Å; V175-Y179 WeakPolarHBondContact O-CD2 3.45Å; T176-Y179 PolarHBondContact O-N 2.99Å; Y179-G183 PolarHBondContact O-N 3.38Å
180	A	97	Very high	94.7	Very high	54 Å²	54	52 Å²	52	45%	0.446	29%	0.287	S	S	.	.	H	α-helix	trans	-64.4	-44	178.1	0	0	0	0	0	112.4	T176 Y178 K184	T176-A180 PolarHBondContact O-N 2.58Å; Y178-A180 VanDerWaalsContact C-N 3.32Å; Y178-A180 PolarHBondContact O-N 3.28Å; A180-K184 WeakPolarHBondContact O-CG 3.45Å; A180-K184 PolarHBondContact O-N 3.38Å; A180-K184 VanDerWaalsContact O-N 3.14Å
181	S	97	Very high	94.2	Very high	55 Å²	55	54.2 Å²	54.2	39%	0.385	29%	0.291	S	S	.	.	H	α-helix	trans	-68.4	-42.7	178.9	-57.8	0	0	0	0	111.4	R177 Y178 K184 L185	R177-S181 VanDerWaalsContact O-CB 3.26Å; R177-S181 WeakPolarHBondContact O-CB 3.39Å; R177-S181 PolarHBondContact O-N 3.44Å; R177-S181 PolarHBondContact O-OG 3.47Å; Y178-S181 PolarHBondContact O-N 3.2Å; S181-K184 WeakPolarHBondContact O-CB 3.44Å; S181-K184 PolarHBondContact O-N 2.96Å; S181-L185 PolarHBondContact O-N 3.02Å
182	R	96.2	Very high	93.8	Very high	12 Å²	12	57 Å²	57	5%	0.045	30%	0.301	C	S	.	.	H	α-helix	trans	-60.8	-46.9	175.7	-166.7	165.2	-167.8	-79.9	3.4	112.4	S106 Y178 K184 L185 V186 M205 D206	S106-R182 PolarHBondContact O-NH1 3.47Å; Y178-R182 VanDerWaalsContact O-CB 3.31Å; Y178-R182 WeakPolarHBondContact O-CB 3.2Å; Y178-R182 PolarHBondContact O-N 3.41Å; Y178-R182 WeakPolarHBondContact OH-CD 3.28Å; Y178-R182 PolarHBondContact OH-NE 2.89Å; R182-K184 VanDerWaalsContact C-N 3.3Å; R182-K184 PolarHBondContact O-N 3.12Å; R182-L185 PolarHBondContact O-N 3.11Å; R182-V186 HydrophobicContact CG-CG2 4.47Å; R182-V186 WeakPolarHBondContact O-CG2 3.44Å; R182-V186 PolarHBondContact O-N 3.25Å; R182-M205 HydrophobicContact CB-CE 3.32Å; R182-M205 HydrophobicContact CB-SD 4.2Å; R182-M205 HydrophobicContact CG-CE 3.39Å; R182-D206 WeakPolarHBondContact CD-OD1 3.39Å; R182-D206 IonicContact CZ-OD1 3.84Å; R182-D206 IonicContact CZ-OD2 3.33Å; R182-D206 IonicContact NE-OD1 3.99Å; R182-D206 PolarHBondContact NE-OD1 2.59Å; R182-D206 IonicContact NE-OD2 3.59Å; R182-D206 PolarHBondContact NE-OD2 2.89Å; R182-D206 IonicContact NH2-OD2 2.88Å; R182-D206 PolarHBondContact NH2-OD2 3.2Å
183	G	94.8	Very high	93.5	Very high	46 Å²	46	54.8 Å²	54.8	47%	0.474	29%	0.29	S	S	.	.	H	α-helix	trans	-58.5	-41.2	176.1	0	0	0	0	0	112.5	Y179 G187	Y179-G183 PolarHBondContact O-N 3.38Å; G183-G187 PolarHBondContact O-N 3.48Å
184	K	95.5	Very high	93	Very high	158 Å²	158	54.9 Å²	54.9	69%	0.687	29%	0.287	S	S	*	.	H	α-helix	trans	-63.1	-45	175.3	-73.8	173.4	-177.8	178.6	0	112.3	A180 S181 R182 G187 K188	A180-K184 WeakPolarHBondContact O-CG 3.45Å; A180-K184 PolarHBondContact O-N 3.38Å; A180-K184 VanDerWaalsContact O-N 3.14Å; S181-K184 WeakPolarHBondContact O-CB 3.44Å; S181-K184 PolarHBondContact O-N 2.96Å; R182-K184 VanDerWaalsContact C-N 3.3Å; R182-K184 PolarHBondContact O-N 3.12Å; K184-G187 PolarHBondContact O-N 3.02Å; K184-K188 WeakPolarHBondContact O-CG 3.34Å; K184-K188 PolarHBondContact O-N 3.27Å
185	L	94.8	Very high	92.8	Very high	30 Å²	30	54.8 Å²	54.8	16%	0.157	29%	0.288	C	S	.	.	H	α-helix	trans	-65.8	-43.2	178.1	-76.9	170.6	0	0	0	112.2	S181 R182 G187 K188 V189 Y198 C201 I202 M205	S181-L185 PolarHBondContact O-N 3.02Å; R182-L185 PolarHBondContact O-N 3.11Å; L185-G187 VanDerWaalsContact C-N 3.25Å; L185-G187 PolarHBondContact O-N 3.44Å; L185-K188 CarbonylContact O-C 3.41Å; L185-K188 WeakPolarHBondContact O-CA 3.5Å; L185-K188 WeakPolarHBondContact O-CB 3.31Å; L185-K188 PolarHBondContact O-N 3.1Å; L185-V189 PolarHBondContact O-N 2.87Å; L185-Y198 HydrophobicContact CD2-CD1 4.23Å; L185-C201 HydrophobicContact CD1-CB 4.44Å; L185-C201 VanDerWaalsContact CD1-SG 3.58Å; L185-C201 HydrophobicContact CD2-CB 4.26Å; L185-I202 HydrophobicContact CB-CD1 4.15Å; L185-I202 HydrophobicContact CB-CG1 3.65Å; L185-I202 HydrophobicContact CD1-CG1 4.28Å; L185-M205 HydrophobicContact CD1-CE 3.92Å; L185-M205 HydrophobicContact CD1-SD 3.65Å
186	V	92.7	Very high	92.6	Very high	22 Å²	22	58.8 Å²	58.8	13%	0.133	31%	0.306	C	S	.	.	H	α-helix	trans	-57.5	-42.1	172.7	171.2	0	0	0	0	110.7	V105 R182 K188 V189 A190 I202	V105-V186 HydrophobicContact CB-CG1 3.83Å; V105-V186 HydrophobicContact CG1-CG1 3.87Å; V105-V186 HydrophobicContact CG1-CG2 4.15Å; V105-V186 HydrophobicContact CG2-CG1 3.9Å; R182-V186 HydrophobicContact CG-CG2 4.47Å; R182-V186 WeakPolarHBondContact O-CG2 3.44Å; R182-V186 PolarHBondContact O-N 3.25Å; V186-K188 VanDerWaalsContact C-N 3.28Å; V186-K188 PolarHBondContact O-N 3.35Å; V186-V189 PolarHBondContact O-N 3.34Å; V186-A190 PolarHBondContact O-N 3.37Å; V186-I202 HydrophobicContact CG2-CD1 3.86Å
187	G	91.1	Very high	92.6	Very high	30 Å²	30	60.5 Å²	60.5	31%	0.309	31%	0.312	S	S	.	.	H	α-helix	trans	-62.5	-30.9	173.2	0	0	0	0	0	113.8	G183 K184 L185 K191	G183-G187 PolarHBondContact O-N 3.48Å; K184-G187 PolarHBondContact O-N 3.02Å; L185-G187 VanDerWaalsContact C-N 3.25Å; L185-G187 PolarHBondContact O-N 3.44Å; G187-K191 VanDerWaalsContact O-CG 3.3Å; G187-K191 WeakPolarHBondContact O-CG 3.43Å; G187-K191 PolarHBondContact O-N 3.41Å; G187-K191 VanDerWaalsContact O-N 3.14Å
188	K	92.7	Very high	92.5	Very high	85 Å²	85	57.4 Å²	57.4	37%	0.37	30%	0.301	S	S	.	.	H	α-helix	trans	-72.6	-41.5	173.2	-70.3	-69.7	-173.2	167.6	0	112	K184 L185 V186 A190 K191 Y192 Y198	K184-K188 WeakPolarHBondContact O-CG 3.34Å; K184-K188 PolarHBondContact O-N 3.27Å; L185-K188 CarbonylContact O-C 3.41Å; L185-K188 WeakPolarHBondContact O-CA 3.5Å; L185-K188 WeakPolarHBondContact O-CB 3.31Å; L185-K188 PolarHBondContact O-N 3.1Å; V186-K188 VanDerWaalsContact C-N 3.28Å; V186-K188 PolarHBondContact O-N 3.35Å; K188-A190 VanDerWaalsContact C-N 3.32Å; K188-A190 PolarHBondContact O-N 3.22Å; K188-K191 PolarHBondContact O-N 3.04Å; K188-Y192 HydrophobicContact CD-CD2 4.24Å; K188-Y192 HydrophobicContact CD-CE2 4.13Å; K188-Y192 PolarHBondContact O-N 3.24Å; K188-Y198 HydrophobicContact CB-CD1 3.78Å; K188-Y198 HydrophobicContact CB-CD2 3.87Å; K188-Y198 HydrophobicContact CB-CE1 3.84Å; K188-Y198 HydrophobicContact CB-CE2 3.89Å; K188-Y198 HydrophobicContact CB-CG 3.83Å; K188-Y198 HydrophobicContact CD-CE1 4.38Å; K188-Y198 HydrophobicContact CD-CE2 4.42Å; K188-Y198 HydrophobicContact CG-CD1 4.42Å; K188-Y198 HydrophobicContact CG-CE1 4.06Å
189	V	90.5	Very high	92.3	Very high	1 Å²	1	58.4 Å²	58.4	1%	0.006	30%	0.304	C	S	.	.	H	α-helix	trans	-59.4	-43.1	172.7	178.9	0	0	0	0	110.9	V54 V56 L185 V186 K191 Y192 P193 R199 I202	V54-V189 HydrophobicContact CG1-CG1 4.12Å; V56-V189 HydrophobicContact CB-CG1 3.83Å; V56-V189 HydrophobicContact CG1-CG1 4.07Å; V56-V189 HydrophobicContact CG2-CG1 4.02Å; L185-V189 PolarHBondContact O-N 2.87Å; V186-V189 PolarHBondContact O-N 3.34Å; V189-K191 VanDerWaalsContact C-N 3.35Å; V189-K191 PolarHBondContact O-N 2.88Å; V189-Y192 CarbonylContact O-C 3.54Å; V189-P193 WeakPolarHBondContact O-CA 3.45Å; V189-P193 WeakPolarHBondContact O-CD 3.39Å; V189-R199 HydrophobicContact CG1-CG 3.95Å; V189-R199 HydrophobicContact CG2-CG 4.09Å; V189-I202 HydrophobicContact CG2-CD1 3.61Å
190	A	87.4	Confident	92.1	Very high	19 Å²	19	59.3 Å²	59.3	16%	0.157	31%	0.312	C	S	.	.	H	α-helix	trans	-64.2	-36.9	176.2	0	0	0	0	0	113.1	V97 L100 V186 K188	V97-A190 WeakPolarHBondContact CB-O 3.47Å; V97-A190 PolarHBondContact N-O 3.33Å; L100-A190 HydrophobicContact CD2-CB 4.47Å; V186-A190 PolarHBondContact O-N 3.37Å; K188-A190 VanDerWaalsContact C-N 3.32Å; K188-A190 PolarHBondContact O-N 3.22Å
191	K	86.7	Confident	92	Very high	112 Å²	112	59.2 Å²	59.2	49%	0.487	31%	0.307	S	S	.	.	H	α-helix	trans	-78.1	-34.9	179.2	-73.7	178.7	-179.7	-175.7	0	113.5	F96 G187 K188 V189 P193	F96-K191 HydrophobicContact CD1-CB 3.87Å; F96-K191 HydrophobicContact CD1-CG 3.88Å; F96-K191 HydrophobicContact CE1-CB 3.97Å; F96-K191 HydrophobicContact CE1-CD 4.36Å; F96-K191 HydrophobicContact CE1-CG 4.03Å; G187-K191 VanDerWaalsContact O-CG 3.3Å; G187-K191 WeakPolarHBondContact O-CG 3.43Å; G187-K191 PolarHBondContact O-N 3.41Å; G187-K191 VanDerWaalsContact O-N 3.14Å; K188-K191 PolarHBondContact O-N 3.04Å; V189-K191 VanDerWaalsContact C-N 3.35Å; V189-K191 PolarHBondContact O-N 2.88Å; K191-P193 VanDerWaalsContact C-CD 3.44Å
192	Y	89.3	Confident	91.9	Very high	74 Å²	74	56.7 Å²	56.7	29%	0.29	29%	0.289	S	S	.	.			trans	-132.3	63.4	-174.3	-50.4	-77	0	0	0	110.3	K188 V189 H194 I195 Y198	K188-Y192 HydrophobicContact CD-CD2 4.24Å; K188-Y192 HydrophobicContact CD-CE2 4.13Å; K188-Y192 PolarHBondContact O-N 3.24Å; V189-Y192 CarbonylContact O-C 3.54Å; Y192-H194 PolarHBondContact O-N 3.46Å; Y192-I195 HydrophobicContact CD1-CD1 4.49Å; Y192-I195 HydrophobicContact CG-CD1 4.19Å; Y192-I195 PolarHBondContact O-N 2.96Å; Y192-Y198 AromaticContact CD2-CE2 3.84Å; Y192-Y198 HydrophobicContact CD2-CE2 3.84Å; Y192-Y198 HydrophobicContact CG-CE2 4.21Å
193	P	87	Confident	91.8	Very high	0 Å²	0	60.8 Å²	60.8	0%	0	30%	0.304	C	S	.	.	T	Hydrogen-bonded Turn	trans	-65.2	-11.6	-175.2	29	-41.6	0	0	0	114.5	P57 Y58 P59 V97 V189 K191	P57-P193 WeakPolarHBondContact O-CB 3.48Å; Y58-P193 VanDerWaalsContact CD1-O 3.27Å; Y58-P193 WeakPolarHBondContact CD1-O 3.38Å; Y58-P193 WeakPolarHBondContact CE1-O 3.4Å; P59-P193 HydrophobicContact CB-CG 4.47Å; P59-P193 HydrophobicContact CG-CG 3.82Å; V97-P193 HydrophobicContact CG2-CB 4.37Å; V97-P193 HydrophobicContact CG2-CG 3.79Å; V189-P193 WeakPolarHBondContact O-CA 3.45Å; V189-P193 WeakPolarHBondContact O-CD 3.39Å; K191-P193 VanDerWaalsContact C-CD 3.44Å
194	H	85.3	Confident	91.7	Very high	94 Å²	94	63.3 Å²	63.3	44%	0.435	31%	0.307	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.1	-5.4	176.7	55.2	-85.5	0	0	0	113.2	Y192	Y192-H194 PolarHBondContact O-N 3.46Å
195	I	90.2	Very high	91.7	Very high	55 Å²	55	56.4 Å²	56.4	28%	0.282	28%	0.277	S	S	.	.			trans	-98.7	101.7	175.9	-59.4	-178.5	0	0	0	108.1	Y192 D197 Y198	Y192-I195 HydrophobicContact CD1-CD1 4.49Å; Y192-I195 HydrophobicContact CG-CD1 4.19Å; Y192-I195 PolarHBondContact O-N 2.96Å; I195-D197 VanDerWaalsContact C-N 3.3Å; I195-D197 HydrophobicContact CG2-CB 4.2Å; I195-D197 PolarHBondContact O-N 3.16Å; I195-Y198 HydrophobicContact CB-CD2 3.8Å; I195-Y198 HydrophobicContact CB-CE2 4.1Å; I195-Y198 HydrophobicContact CD1-CE2 3.95Å; I195-Y198 HydrophobicContact CG2-CD2 3.78Å; I195-Y198 HydrophobicContact CG2-CE2 4Å; I195-Y198 HydrophobicContact CG2-CG 4.35Å; I195-Y198 PolarHBondContact O-N 3.15Å
196	E	90.8	Very high	91.7	Very high	87 Å²	87	55 Å²	55	41%	0.407	27%	0.27	S	S	.	.	T	Hydrogen-bonded Turn	trans	-67.2	-29.1	-176	-66.4	-57.6	86.2	0	0	113.6	Y58 Y198 R199 E200	Y58-E196 WeakPolarHBondContact CE1-OE1 3.48Å; Y58-E196 PolarHBondContact OH-OE1 3.38Å; Y58-E196 VanDerWaalsContact OH-OE1 3.05Å; Y58-E196 PolarHBondContact OH-OE2 3.08Å; E196-Y198 PolarHBondContact O-N 3.44Å; E196-Y198 VanDerWaalsContact O-N 3.09Å; E196-R199 WeakPolarHBondContact O-CB 3.31Å; E196-R199 PolarHBondContact O-N 3.32Å; E196-R199 IonicContact OE1-NE 3.89Å; E196-E200 PolarHBondContact O-N 3.01Å; E196-E200 VanDerWaalsContact O-N 3.08Å
197	D	95.7	Very high	91.7	Very high	125 Å²	125	57.3 Å²	57.3	67%	0.668	28%	0.279	S	S	*	.	H	α-helix	trans	-56.3	-29.8	176.7	-63	-72.8	0	0	0	112.6	I195 C201	I195-D197 VanDerWaalsContact C-N 3.3Å; I195-D197 HydrophobicContact CG2-CB 4.2Å; I195-D197 PolarHBondContact O-N 3.16Å; D197-C201 WeakPolarHBondContact O-CB 3.4Å; D197-C201 PolarHBondContact O-N 3.32Å
198	Y	94.3	Very high	91.8	Very high	59 Å²	59	61.7 Å²	61.7	23%	0.231	29%	0.29	C	S	.	.	H	α-helix	trans	-70.6	-30.9	176.3	-70.6	-45.8	0	0	0	113	L185 K188 Y192 I195 E196 I202	L185-Y198 HydrophobicContact CD2-CD1 4.23Å; K188-Y198 HydrophobicContact CB-CD1 3.78Å; K188-Y198 HydrophobicContact CB-CD2 3.87Å; K188-Y198 HydrophobicContact CB-CE1 3.84Å; K188-Y198 HydrophobicContact CB-CE2 3.89Å; K188-Y198 HydrophobicContact CB-CG 3.83Å; K188-Y198 HydrophobicContact CD-CE1 4.38Å; K188-Y198 HydrophobicContact CD-CE2 4.42Å; K188-Y198 HydrophobicContact CG-CD1 4.42Å; K188-Y198 HydrophobicContact CG-CE1 4.06Å; Y192-Y198 AromaticContact CD2-CE2 3.84Å; Y192-Y198 HydrophobicContact CD2-CE2 3.84Å; Y192-Y198 HydrophobicContact CG-CE2 4.21Å; I195-Y198 HydrophobicContact CB-CD2 3.8Å; I195-Y198 HydrophobicContact CB-CE2 4.1Å; I195-Y198 HydrophobicContact CD1-CE2 3.95Å; I195-Y198 HydrophobicContact CG2-CD2 3.78Å; I195-Y198 HydrophobicContact CG2-CE2 4Å; I195-Y198 HydrophobicContact CG2-CG 4.35Å; I195-Y198 PolarHBondContact O-N 3.15Å; E196-Y198 PolarHBondContact O-N 3.44Å; E196-Y198 VanDerWaalsContact O-N 3.09Å; Y198-I202 WeakPolarHBondContact O-CG1 3.49Å; Y198-I202 PolarHBondContact O-N 3.24Å
199	R	92.3	Very high	92	Very high	29 Å²	29	58.1 Å²	58.1	11%	0.109	28%	0.275	C	S	.	.	H	α-helix	trans	-75.1	-45.6	175.3	-63.5	179.1	-172.1	-87.8	2.8	110.5	V54 V56 Y58 V189 E196 C201 I202 R203	V54-R199 PolarHBondContact O-NH1 2.99Å; V54-R199 VanDerWaalsContact O-NH1 3.09Å; V56-R199 PolarHBondContact O-NH1 3.17Å; V56-R199 VanDerWaalsContact O-NH1 3.07Å; V56-R199 PolarHBondContact O-NH2 3.4Å; Y58-R199 WeakPolarHBondContact OH-CD 3.46Å; Y58-R199 PolarHBondContact OH-NE 2.99Å; V189-R199 HydrophobicContact CG1-CG 3.95Å; V189-R199 HydrophobicContact CG2-CG 4.09Å; E196-R199 WeakPolarHBondContact O-CB 3.31Å; E196-R199 PolarHBondContact O-N 3.32Å; E196-R199 IonicContact OE1-NE 3.89Å; R199-C201 VanDerWaalsContact C-N 3.32Å; R199-C201 PolarHBondContact O-N 3.04Å; R199-I202 PolarHBondContact O-N 3.27Å; R199-I202 VanDerWaalsContact O-N 3.15Å; R199-R203 PolarHBondContact O-N 3.47Å
200	E	93.3	Very high	92.2	Very high	99 Å²	99	58.1 Å²	58.1	46%	0.463	28%	0.275	S	S	.	.	H	α-helix	trans	-62.6	-38.7	175.6	-71.9	-58.6	119.3	0	0	111.7	E196 I202 R203 D204	E196-E200 PolarHBondContact O-N 3.01Å; E196-E200 VanDerWaalsContact O-N 3.08Å; E200-I202 VanDerWaalsContact C-N 3.28Å; E200-I202 PolarHBondContact O-N 3.17Å; E200-R203 WeakPolarHBondContact O-CB 3.37Å; E200-R203 PolarHBondContact O-N 3.09Å; E200-R203 WeakPolarHBondContact OE1-CD 3.36Å; E200-R203 IonicContact OE1-CZ 3.91Å; E200-R203 IonicContact OE1-NH1 2.64Å; E200-R203 PolarHBondContact OE1-NH1 3.32Å; E200-R203 IonicContact OE2-CZ 3.1Å; E200-R203 IonicContact OE2-NH1 3.75Å; E200-R203 PolarHBondContact OE2-NH1 2.97Å; E200-D204 PolarHBondContact O-N 2.68Å
201	C	95.2	Very high	92.5	Very high	52 Å²	52	62 Å²	62	35%	0.351	29%	0.292	S	S	.	.	H	α-helix	trans	-62.6	-32.3	175.1	-174	0	0	0	0	113	L185 D197 R199 M205	L185-C201 HydrophobicContact CD1-CB 4.44Å; L185-C201 VanDerWaalsContact CD1-SG 3.58Å; L185-C201 HydrophobicContact CD2-CB 4.26Å; D197-C201 WeakPolarHBondContact O-CB 3.4Å; D197-C201 PolarHBondContact O-N 3.32Å; R199-C201 VanDerWaalsContact C-N 3.32Å; R199-C201 PolarHBondContact O-N 3.04Å; C201-M205 WeakPolarHBondContact O-CB 3.3Å; C201-M205 PolarHBondContact O-N 3.01Å
202	I	94.3	Very high	93	Very high	1 Å²	1	57.9 Å²	57.9	1%	0.005	28%	0.276	C	S	.	.	H	α-helix	trans	-67.9	-41.3	173.1	-67.9	166.5	0	0	0	110.6	V54 L185 V186 V189 Y198 R199 E200 M205 D206	V54-I202 HydrophobicContact CG1-CD1 4.23Å; V54-I202 HydrophobicContact CG2-CB 4.38Å; V54-I202 HydrophobicContact CG2-CD1 3.83Å; V54-I202 HydrophobicContact CG2-CG2 3.8Å; L185-I202 HydrophobicContact CB-CD1 4.15Å; L185-I202 HydrophobicContact CB-CG1 3.65Å; L185-I202 HydrophobicContact CD1-CG1 4.28Å; V186-I202 HydrophobicContact CG2-CD1 3.86Å; V189-I202 HydrophobicContact CG2-CD1 3.61Å; Y198-I202 WeakPolarHBondContact O-CG1 3.49Å; Y198-I202 PolarHBondContact O-N 3.24Å; R199-I202 PolarHBondContact O-N 3.27Å; R199-I202 VanDerWaalsContact O-N 3.15Å; E200-I202 VanDerWaalsContact C-N 3.28Å; E200-I202 PolarHBondContact O-N 3.17Å; I202-M205 PolarHBondContact O-N 3.11Å; I202-D206 WeakPolarHBondContact O-CB 3.3Å; I202-D206 PolarHBondContact O-N 3.22Å
203	R	93	Very high	93.3	Very high	98 Å²	98	54.4 Å²	54.4	37%	0.37	26%	0.262	S	S	.	.	H	α-helix	trans	-62.6	-51	177	-67.2	178.4	61.7	-160.9	-3.7	111.4	H51 R199 E200 M205 D206 E207	H51-R203 PolarHBondContact CE1-NH2 3.37Å; H51-R203 PolarHBondContact ND1-NH2 3.2Å; R199-R203 PolarHBondContact O-N 3.47Å; E200-R203 WeakPolarHBondContact O-CB 3.37Å; E200-R203 PolarHBondContact O-N 3.09Å; E200-R203 WeakPolarHBondContact OE1-CD 3.36Å; E200-R203 IonicContact OE1-CZ 3.91Å; E200-R203 IonicContact OE1-NH1 2.64Å; E200-R203 PolarHBondContact OE1-NH1 3.32Å; E200-R203 IonicContact OE2-CZ 3.1Å; E200-R203 IonicContact OE2-NH1 3.75Å; E200-R203 PolarHBondContact OE2-NH1 2.97Å; R203-M205 VanDerWaalsContact C-N 3.33Å; R203-M205 PolarHBondContact O-N 2.94Å; R203-D206 PolarHBondContact O-N 3.05Å; R203-D206 VanDerWaalsContact O-N 3.17Å; R203-E207 PolarHBondContact O-N 2.72Å
204	D	93.3	Very high	93.8	Very high	99 Å²	99	58.1 Å²	58.1	53%	0.529	28%	0.277	S	S	.	.	H	α-helix	trans	-58.9	-43.1	177.5	178.7	79.4	0	0	0	111.9	E200 D206 E207 K208	E200-D204 PolarHBondContact O-N 2.68Å; D204-D206 PolarHBondContact O-N 3.49Å; D204-E207 PolarHBondContact O-N 2.97Å; D204-K208 WeakPolarHBondContact O-CB 3.44Å; D204-K208 PolarHBondContact O-N 3.29Å
205	M	94.7	Very high	94.3	Very high	13 Å²	13	58.8 Å²	58.8	6%	0.064	28%	0.276	C	S	.	.	H	α-helix	trans	-68.1	-34.6	177.5	173.4	-165.8	68.4	0	0	112.7	Y178 R182 L185 C201 I202 R203 Q209	Y178-M205 HydrophobicContact CD2-CG 4.32Å; Y178-M205 HydrophobicContact CE2-CE 4.24Å; Y178-M205 HydrophobicContact CE2-CG 4.34Å; R182-M205 HydrophobicContact CB-CE 3.32Å; R182-M205 HydrophobicContact CB-SD 4.2Å; R182-M205 HydrophobicContact CG-CE 3.39Å; L185-M205 HydrophobicContact CD1-CE 3.92Å; L185-M205 HydrophobicContact CD1-SD 3.65Å; C201-M205 WeakPolarHBondContact O-CB 3.3Å; C201-M205 PolarHBondContact O-N 3.01Å; I202-M205 PolarHBondContact O-N 3.11Å; R203-M205 VanDerWaalsContact C-N 3.33Å; R203-M205 PolarHBondContact O-N 2.94Å; M205-Q209 WeakPolarHBondContact O-CB 3.38Å; M205-Q209 PolarHBondContact O-N 3.4Å
206	D	94.8	Very high	94.7	Very high	0 Å²	0	56.2 Å²	56.2	0%	0	26%	0.263	C	S	.	.	H	α-helix	trans	-66.3	-43.8	173	-76.4	-7.3	0	0	0	110.4	V50 N108 I111 Y178 R182 I202 R203 D204 Q209 A210	V50-D206 HydrophobicContact CG1-CB 4.48Å; V50-D206 WeakPolarHBondContact CG1-O 3.48Å; N108-D206 PolarHBondContact ND2-OD2 3.16Å; I111-D206 WeakPolarHBondContact CD1-O 3.41Å; Y178-D206 WeakPolarHBondContact CE2-OD1 3.47Å; Y178-D206 PolarHBondContact OH-OD1 2.86Å; R182-D206 WeakPolarHBondContact CD-OD1 3.39Å; R182-D206 IonicContact CZ-OD1 3.84Å; R182-D206 IonicContact CZ-OD2 3.33Å; R182-D206 IonicContact NE-OD1 3.99Å; R182-D206 PolarHBondContact NE-OD1 2.59Å; R182-D206 IonicContact NE-OD2 3.59Å; R182-D206 PolarHBondContact NE-OD2 2.89Å; R182-D206 IonicContact NH2-OD2 2.88Å; R182-D206 PolarHBondContact NH2-OD2 3.2Å; I202-D206 WeakPolarHBondContact O-CB 3.3Å; I202-D206 PolarHBondContact O-N 3.22Å; R203-D206 PolarHBondContact O-N 3.05Å; R203-D206 VanDerWaalsContact O-N 3.17Å; D204-D206 PolarHBondContact O-N 3.49Å; D206-Q209 PolarHBondContact O-N 3.26Å; D206-A210 PolarHBondContact O-N 2.83Å
207	E	93.4	Very high	95	Very high	71 Å²	71	52 Å²	52	33%	0.332	24%	0.243	S	C	.	.	H	α-helix	trans	-58.7	-50.3	173	-72.5	-177	-173.6	0	0	112.3	H51 R203 D204 Q209 A210 I211	H51-E207 IonicContact CD2-OE1 3.18Å; H51-E207 IonicContact CE1-OE1 3.56Å; H51-E207 PolarHBondContact CE1-OE1 3.13Å; H51-E207 VanDerWaalsContact CE1-OE1 3.3Å; H51-E207 IonicContact NE2-OE1 2.78Å; H51-E207 PolarHBondContact NE2-OE1 2.99Å; R203-E207 PolarHBondContact O-N 2.72Å; D204-E207 PolarHBondContact O-N 2.97Å; E207-Q209 PolarHBondContact O-N 3.04Å; E207-A210 PolarHBondContact O-N 3.26Å; E207-A210 VanDerWaalsContact O-N 3.11Å; E207-I211 WeakPolarHBondContact O-CG1 3.47Å; E207-I211 PolarHBondContact O-N 3.35Å
208	K	94.3	Very high	95.1	Very high	122 Å²	122	48.7 Å²	48.7	53%	0.53	22%	0.224	S	C	.	.	H	α-helix	trans	-56	-39.9	175.9	-173.1	-172.3	71	170	0	111.2	D204 I211 T212	D204-K208 WeakPolarHBondContact O-CB 3.44Å; D204-K208 PolarHBondContact O-N 3.29Å; K208-I211 PolarHBondContact O-N 2.9Å; K208-T212 WeakPolarHBondContact O-CB 3.37Å; K208-T212 PolarHBondContact O-N 2.94Å; K208-T212 PolarHBondContact O-OG1 3.45Å
209	Q	95.6	Very high	95.3	Very high	10 Å²	10	47.8 Å²	47.8	5%	0.047	22%	0.222	C	C	.	.	H	α-helix	trans	-67.6	-40.8	178.7	-170.7	61.9	29	0	0	111.8	I111 Y178 M205 D206 E207 T212 M213	I111-Q209 HydrophobicContact CD1-CB 4.22Å; I111-Q209 HydrophobicContact CD1-CG 4.41Å; I111-Q209 HydrophobicContact CG2-CB 4.24Å; I111-Q209 HydrophobicContact CG2-CG 3.51Å; Y178-Q209 HydrophobicContact CD1-CG 4.08Å; Y178-Q209 HydrophobicContact CD2-CB 3.6Å; Y178-Q209 HydrophobicContact CD2-CG 3.48Å; Y178-Q209 VanDerWaalsContact CD2-CG 3.48Å; Y178-Q209 HydrophobicContact CE1-CG 4.3Å; Y178-Q209 HydrophobicContact CE2-CB 3.59Å; Y178-Q209 HydrophobicContact CE2-CG 3.73Å; Y178-Q209 HydrophobicContact CG-CB 4.31Å; Y178-Q209 HydrophobicContact CG-CG 3.66Å; M205-Q209 WeakPolarHBondContact O-CB 3.38Å; M205-Q209 PolarHBondContact O-N 3.4Å; D206-Q209 PolarHBondContact O-N 3.26Å; E207-Q209 PolarHBondContact O-N 3.04Å; Q209-T212 WeakPolarHBondContact O-CB 3.38Å; Q209-T212 PolarHBondContact O-N 2.78Å; Q209-M213 HydrophobicContact CG-CG 4.44Å; Q209-M213 VanDerWaalsContact O-CG 3.3Å; Q209-M213 WeakPolarHBondContact O-CG 3.4Å; Q209-M213 PolarHBondContact O-N 3.32Å
210	A	95	Very high	95.6	Very high	1 Å²	1	46.4 Å²	46.4	1%	0.008	22%	0.217	C	C	.	.	H	α-helix	trans	-60.4	-46.3	174.9	0	0	0	0	0	111.8	L45 V50 I111 M114 D206 E207 T212 M213 R214	L45-A210 HydrophobicContact CD2-CB 3.88Å; V50-A210 HydrophobicContact CB-CB 4.45Å; V50-A210 HydrophobicContact CG1-CB 3.59Å; V50-A210 HydrophobicContact CG2-CB 3.91Å; I111-A210 HydrophobicContact CD1-CB 3.66Å; M114-A210 HydrophobicContact CE-CB 4.31Å; M114-A210 WeakPolarHBondContact CE-O 3.42Å; M114-A210 HydrophobicContact SD-CB 3.96Å; D206-A210 PolarHBondContact O-N 2.83Å; E207-A210 PolarHBondContact O-N 3.26Å; E207-A210 VanDerWaalsContact O-N 3.11Å; A210-T212 VanDerWaalsContact C-N 3.28Å; A210-T212 PolarHBondContact O-N 3.35Å; A210-M213 PolarHBondContact O-N 2.65Å; A210-R214 PolarHBondContact O-N 3.42Å
211	I	94.5	Very high	95.9	Very high	100 Å²	100	44.9 Å²	44.9	51%	0.513	21%	0.207	S	C	.	.	H	α-helix	trans	-57.7	-44.7	175.3	-64.5	166.6	0	0	0	110.3	L45 E207 K208 R214 Y215	L45-I211 HydrophobicContact CD1-CG1 4.07Å; L45-I211 HydrophobicContact CD2-CG1 4.49Å; E207-I211 WeakPolarHBondContact O-CG1 3.47Å; E207-I211 PolarHBondContact O-N 3.35Å; K208-I211 PolarHBondContact O-N 2.9Å; I211-R214 PolarHBondContact O-N 2.83Å; I211-Y215 WeakPolarHBondContact O-CB 3.46Å; I211-Y215 PolarHBondContact O-N 3.14Å
212	T	96.1	Very high	96	Very high	27 Å²	27	44.9 Å²	44.9	17%	0.166	20%	0.204	C	C	.	.	H	α-helix	trans	-63.9	-41.9	179.3	-57.4	0	0	0	0	112	K208 Q209 A210 Y215 I216	K208-T212 WeakPolarHBondContact O-CB 3.37Å; K208-T212 PolarHBondContact O-N 2.94Å; K208-T212 PolarHBondContact O-OG1 3.45Å; Q209-T212 WeakPolarHBondContact O-CB 3.38Å; Q209-T212 PolarHBondContact O-N 2.78Å; A210-T212 VanDerWaalsContact C-N 3.28Å; A210-T212 PolarHBondContact O-N 3.35Å; T212-Y215 PolarHBondContact O-N 3.39Å; T212-I216 HydrophobicContact CG2-CD1 3.96Å; T212-I216 WeakPolarHBondContact O-CG1 3.37Å; T212-I216 PolarHBondContact O-N 3.32Å
213	M	96.6	Very high	96.2	Very high	0 Å²	0	45.7 Å²	45.7	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-63.6	-41.9	177	-66.2	-61.6	77.8	0	0	111.7	F43 M114 I115 V175 Q209 A210 I216 I217	F43-M213 HydrophobicContact CE1-CB 4.19Å; M114-M213 HydrophobicContact CB-CB 3.99Å; M114-M213 HydrophobicContact CB-CG 3.96Å; M114-M213 HydrophobicContact CE-CB 3.77Å; M114-M213 HydrophobicContact SD-CB 4.25Å; I115-M213 HydrophobicContact CB-SD 4.33Å; I115-M213 HydrophobicContact CG1-CG 4.3Å; I115-M213 HydrophobicContact CG1-SD 3.4Å; I115-M213 WeakPolarHBondContact CG1-SD 3.5Å; V175-M213 HydrophobicContact CG2-CE 4.11Å; V175-M213 HydrophobicContact CG2-SD 4.49Å; Q209-M213 HydrophobicContact CG-CG 4.44Å; Q209-M213 VanDerWaalsContact O-CG 3.3Å; Q209-M213 WeakPolarHBondContact O-CG 3.4Å; Q209-M213 PolarHBondContact O-N 3.32Å; A210-M213 PolarHBondContact O-N 2.65Å; M213-I216 HydrophobicContact CE-CD1 3.6Å; M213-I216 PolarHBondContact O-N 3.25Å; M213-I217 PolarHBondContact O-N 3.3Å
214	R	96.3	Very high	96.5	Very high	79 Å²	79	41.1 Å²	41.1	30%	0.298	19%	0.19	S	C	.	.	H	α-helix	trans	-63.9	-45.2	174.5	-170.5	-178.4	-176.9	-75.2	-3.6	111.9	L38 F43 A210 I211 I216 I217 M218	L38-R214 HydrophobicContact CD2-CG 3.74Å; F43-R214 HydrophobicContact CB-CG 4.49Å; F43-R214 HydrophobicContact CD1-CB 4.08Å; F43-R214 HydrophobicContact CD1-CG 4.37Å; F43-R214 WeakPolarHBondContact O-CD 3.43Å; F43-R214 PolarHBondContact O-NE 3.26Å; A210-R214 PolarHBondContact O-N 3.42Å; I211-R214 PolarHBondContact O-N 2.83Å; R214-I216 VanDerWaalsContact C-N 3.33Å; R214-I216 PolarHBondContact O-N 3.41Å; R214-I217 PolarHBondContact O-N 3.01Å; R214-M218 PolarHBondContact NH1-SD 2.95Å; R214-M218 WeakPolarHBondContact O-CG 3.34Å; R214-M218 PolarHBondContact O-N 3.26Å; R214-M218 VanDerWaalsContact O-N 3.14Å
215	Y	96.6	Very high	96.7	Very high	108 Å²	108	38.3 Å²	38.3	42%	0.424	18%	0.18	S	C	.	.	H	α-helix	trans	-57.7	-44.5	176.6	171.8	-109.5	0	0	0	111.8	F171 I211 T212 I217 M218 E219	F171-Y215 HydrophobicContact CE1-CE1 4.21Å; F171-Y215 HydrophobicContact CZ-CE1 4.31Å; I211-Y215 WeakPolarHBondContact O-CB 3.46Å; I211-Y215 PolarHBondContact O-N 3.14Å; T212-Y215 PolarHBondContact O-N 3.39Å; Y215-I217 VanDerWaalsContact C-N 3.33Å; Y215-I217 PolarHBondContact O-N 3.17Å; Y215-M218 WeakPolarHBondContact O-CA 3.22Å; Y215-M218 VanDerWaalsContact O-CB 3.32Å; Y215-M218 WeakPolarHBondContact O-CB 3.31Å; Y215-M218 PolarHBondContact O-N 2.96Å; Y215-E219 HydrophobicContact CD1-CG 4.29Å; Y215-E219 HydrophobicContact CD2-CG 4.16Å; Y215-E219 HydrophobicContact CE1-CG 3.77Å; Y215-E219 HydrophobicContact CE2-CG 3.58Å; Y215-E219 HydrophobicContact CG-CG 4.48Å; Y215-E219 PolarHBondContact O-N 3.04Å; Y215-E219 VanDerWaalsContact OH-CD 3.29Å; Y215-E219 PolarHBondContact OH-OE2 2.99Å
216	I	98	Very high	96.9	Very high	0 Å²	0	40.7 Å²	40.7	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-61.5	-39	178.7	-72.5	165.2	0	0	0	112	T118 L122 F171 T212 M213 R214 M218 E219 I220	T118-I216 HydrophobicContact CG2-CB 4.14Å; T118-I216 HydrophobicContact CG2-CG2 3.51Å; L122-I216 HydrophobicContact CD1-CG2 4.29Å; L122-I216 HydrophobicContact CD2-CG2 4.49Å; F171-I216 HydrophobicContact CB-CD1 3.85Å; F171-I216 HydrophobicContact CB-CG1 4.17Å; F171-I216 HydrophobicContact CB-CG2 4.39Å; F171-I216 HydrophobicContact CD1-CD1 3.87Å; F171-I216 HydrophobicContact CD1-CG1 3.69Å; F171-I216 HydrophobicContact CD2-CG1 4.24Å; F171-I216 HydrophobicContact CD2-CG2 4.27Å; F171-I216 HydrophobicContact CE1-CG1 4.11Å; F171-I216 HydrophobicContact CG-CD1 3.95Å; F171-I216 HydrophobicContact CG-CG1 3.78Å; F171-I216 HydrophobicContact CG-CG2 4.35Å; T212-I216 HydrophobicContact CG2-CD1 3.96Å; T212-I216 WeakPolarHBondContact O-CG1 3.37Å; T212-I216 PolarHBondContact O-N 3.32Å; M213-I216 HydrophobicContact CE-CD1 3.6Å; M213-I216 PolarHBondContact O-N 3.25Å; R214-I216 VanDerWaalsContact C-N 3.33Å; R214-I216 PolarHBondContact O-N 3.41Å; I216-M218 VanDerWaalsContact C-N 3.32Å; I216-M218 PolarHBondContact O-N 3.48Å; I216-E219 PolarHBondContact O-N 2.89Å; I216-I220 HydrophobicContact CG2-CD1 4Å; I216-I220 HydrophobicContact CG2-CG1 4.42Å; I216-I220 VanDerWaalsContact O-CG1 3.26Å; I216-I220 WeakPolarHBondContact O-CG1 3.26Å; I216-I220 PolarHBondContact O-N 3.22Å
217	I	98.2	Very high	97	Very high	0 Å²	0	40.8 Å²	40.8	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-64.1	-38.9	174.2	-60.2	-64.8	0	0	0	111.2	M34 I37 L38 F43 T118 M213 R214 Y215 E219 I220 R221	M34-I217 HydrophobicContact CB-CG2 4.06Å; M34-I217 HydrophobicContact SD-CG2 4.11Å; I37-I217 HydrophobicContact CB-CG2 4.3Å; I37-I217 HydrophobicContact CG2-CD1 4.26Å; I37-I217 HydrophobicContact CG2-CG1 4.22Å; I37-I217 HydrophobicContact CG2-CG2 4.05Å; L38-I217 HydrophobicContact CD1-CG2 4.12Å; L38-I217 HydrophobicContact CD2-CB 3.93Å; L38-I217 HydrophobicContact CD2-CG2 3.84Å; L38-I217 HydrophobicContact CG-CB 4.27Å; L38-I217 HydrophobicContact CG-CG2 3.6Å; F43-I217 HydrophobicContact CD1-CG1 4.32Å; F43-I217 HydrophobicContact CE1-CG1 3.65Å; F43-I217 HydrophobicContact CZ-CD1 4.36Å; F43-I217 HydrophobicContact CZ-CG1 3.86Å; T118-I217 HydrophobicContact CG2-CD1 3.91Å; T118-I217 HydrophobicContact CG2-CG1 4.44Å; M213-I217 PolarHBondContact O-N 3.3Å; R214-I217 PolarHBondContact O-N 3.01Å; Y215-I217 VanDerWaalsContact C-N 3.33Å; Y215-I217 PolarHBondContact O-N 3.17Å; I217-E219 VanDerWaalsContact C-N 3.34Å; I217-I220 HydrophobicContact CD1-CD1 4.24Å; I217-I220 PolarHBondContact O-N 2.99Å; I217-R221 PolarHBondContact O-N 3.24Å
218	M	97.9	Very high	97.3	Very high	54 Å²	54	39.8 Å²	39.8	27%	0.266	19%	0.192	S	C	.	.	H	α-helix	trans	-61.6	-42.5	174.1	-63.7	172	60.4	0	0	111.6	L38 R214 Y215 I216 R221 N222	L38-M218 HydrophobicContact CD1-CG 3.8Å; L38-M218 HydrophobicContact CD2-CG 3.8Å; L38-M218 HydrophobicContact CG-CG 4.49Å; R214-M218 PolarHBondContact NH1-SD 2.95Å; R214-M218 WeakPolarHBondContact O-CG 3.34Å; R214-M218 PolarHBondContact O-N 3.26Å; R214-M218 VanDerWaalsContact O-N 3.14Å; Y215-M218 WeakPolarHBondContact O-CA 3.22Å; Y215-M218 VanDerWaalsContact O-CB 3.32Å; Y215-M218 WeakPolarHBondContact O-CB 3.31Å; Y215-M218 PolarHBondContact O-N 2.96Å; I216-M218 VanDerWaalsContact C-N 3.32Å; I216-M218 PolarHBondContact O-N 3.48Å; M218-R221 WeakPolarHBondContact O-CB 3.45Å; M218-R221 PolarHBondContact O-N 3.41Å; M218-N222 WeakPolarHBondContact O-CB 3.33Å; M218-N222 PolarHBondContact O-N 3.15Å; M218-N222 PolarHBondContact O-ND2 3.5Å; M218-N222 PolarHBondContact O-OD1 2.98Å
219	E	98.3	Very high	97.4	Very high	40 Å²	40	37.5 Å²	37.5	19%	0.187	19%	0.185	C	C	.	.	H	α-helix	trans	-66.6	-40.6	177.6	-66.7	-61.4	85.8	0	0	111.9	F171 Y215 I216 I217 R221 N222 H223	F171-E219 HydrophobicContact CE2-CB 4.09Å; F171-E219 HydrophobicContact CE2-CG 4.5Å; F171-E219 HydrophobicContact CZ-CB 4.25Å; F171-E219 HydrophobicContact CZ-CG 4.16Å; Y215-E219 HydrophobicContact CD1-CG 4.29Å; Y215-E219 HydrophobicContact CD2-CG 4.16Å; Y215-E219 HydrophobicContact CE1-CG 3.77Å; Y215-E219 HydrophobicContact CE2-CG 3.58Å; Y215-E219 HydrophobicContact CG-CG 4.48Å; Y215-E219 PolarHBondContact O-N 3.04Å; Y215-E219 VanDerWaalsContact OH-CD 3.29Å; Y215-E219 PolarHBondContact OH-OE2 2.99Å; I216-E219 PolarHBondContact O-N 2.89Å; I217-E219 VanDerWaalsContact C-N 3.34Å; E219-R221 VanDerWaalsContact C-N 3.31Å; E219-R221 PolarHBondContact O-N 2.88Å; E219-N222 PolarHBondContact O-N 3.22Å; E219-N222 VanDerWaalsContact O-N 3.16Å; E219-N222 PolarHBondContact OE1-ND2 2.83Å; E219-H223 WeakPolarHBondContact O-CB 3.33Å; E219-H223 PolarHBondContact O-CD2 3.09Å; E219-H223 VanDerWaalsContact O-CG 3.26Å; E219-H223 PolarHBondContact O-N 3.31Å
220	I	98.6	Very high	97.5	Very high	0 Å²	0	38.9 Å²	38.9	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-57	-47.5	173.3	-65.8	163.3	0	0	0	110.3	M34 C121 L122 L125 I216 I217 N222 H223 Y224	M34-I220 HydrophobicContact CG-CB 4.33Å; M34-I220 HydrophobicContact CG-CG2 3.81Å; M34-I220 HydrophobicContact SD-CB 4.2Å; M34-I220 HydrophobicContact SD-CG2 3.63Å; C121-I220 HydrophobicContact CB-CD1 3.9Å; L122-I220 HydrophobicContact CB-CD1 4.12Å; L122-I220 HydrophobicContact CD1-CD1 4.11Å; L122-I220 HydrophobicContact CD1-CG1 4.06Å; L125-I220 HydrophobicContact CB-CG2 4.36Å; L125-I220 HydrophobicContact CD2-CB 4.32Å; L125-I220 HydrophobicContact CD2-CG1 3.95Å; L125-I220 HydrophobicContact CD2-CG2 4.28Å; I216-I220 HydrophobicContact CG2-CD1 4Å; I216-I220 HydrophobicContact CG2-CG1 4.42Å; I216-I220 VanDerWaalsContact O-CG1 3.26Å; I216-I220 WeakPolarHBondContact O-CG1 3.26Å; I216-I220 PolarHBondContact O-N 3.22Å; I217-I220 HydrophobicContact CD1-CD1 4.24Å; I217-I220 PolarHBondContact O-N 2.99Å; I220-N222 PolarHBondContact O-N 3.45Å; I220-H223 PolarHBondContact O-N 3.38Å; I220-Y224 HydrophobicContact CG2-CD2 3.8Å; I220-Y224 HydrophobicContact CG2-CE2 3.49Å; I220-Y224 VanDerWaalsContact CG2-CE2 3.49Å; I220-Y224 WeakPolarHBondContact O-CD2 3.46Å; I220-Y224 PolarHBondContact O-N 3.37Å; I220-Y224 VanDerWaalsContact O-N 3.13Å
221	R	98.6	Very high	97.7	Very high	67 Å²	67	38.8 Å²	38.8	25%	0.253	19%	0.192	S	C	.	.	H	α-helix	trans	-58.2	-47.5	175.6	-174.3	-164.4	63.6	-171.9	-2	111.6	V31 M34 I217 M218 E219 Y224 A225	V31-R221 HydrophobicContact CG1-CG 3.9Å; M34-R221 HydrophobicContact CB-CB 3.63Å; M34-R221 HydrophobicContact CB-CG 4.09Å; M34-R221 HydrophobicContact CG-CB 4.12Å; I217-R221 PolarHBondContact O-N 3.24Å; M218-R221 WeakPolarHBondContact O-CB 3.45Å; M218-R221 PolarHBondContact O-N 3.41Å; E219-R221 VanDerWaalsContact C-N 3.31Å; E219-R221 PolarHBondContact O-N 2.88Å; R221-Y224 PolarHBondContact O-N 3.33Å; R221-A225 WeakPolarHBondContact O-CB 3.17Å; R221-A225 PolarHBondContact O-N 3.45Å
222	N	98.4	Very high	97.8	Very high	53 Å²	53	37.4 Å²	37.4	28%	0.283	19%	0.185	S	C	.	.	H	α-helix	trans	-63.2	-45.9	-177.5	-65.3	-14.6	0	0	0	110.6	M218 E219 I220 Y224 A225 T226	M218-N222 WeakPolarHBondContact O-CB 3.33Å; M218-N222 PolarHBondContact O-N 3.15Å; M218-N222 PolarHBondContact O-ND2 3.5Å; M218-N222 PolarHBondContact O-OD1 2.98Å; E219-N222 PolarHBondContact O-N 3.22Å; E219-N222 VanDerWaalsContact O-N 3.16Å; E219-N222 PolarHBondContact OE1-ND2 2.83Å; I220-N222 PolarHBondContact O-N 3.45Å; N222-Y224 PolarHBondContact O-N 2.89Å; N222-A225 PolarHBondContact O-N 3.27Å; N222-A225 VanDerWaalsContact O-N 3.15Å; N222-T226 WeakPolarHBondContact O-CG2 3.12Å; N222-T226 PolarHBondContact O-N 2.91Å; N222-T226 PolarHBondContact O-OG1 3.07Å; N222-T226 VanDerWaalsContact O-OG1 3.12Å
223	H	98.4	Very high	97.9	Very high	17 Å²	17	42.6 Å²	42.6	8%	0.079	21%	0.205	C	C	.	.	H	α-helix	trans	-59.2	-43.6	177.2	-70.6	-47.8	0	0	0	112.6	L125 I164 D167 E219 I220 T226 L227	L125-H223 HydrophobicContact CD1-CB 4.1Å; L125-H223 HydrophobicContact CD2-CB 4.28Å; I164-H223 HydrophobicContact CD1-CB 3.99Å; I164-H223 HydrophobicContact CG1-CB 4.04Å; I164-H223 HydrophobicContact CG2-CB 4.31Å; D167-H223 IonicContact OD2-CE1 3.45Å; D167-H223 IonicContact OD2-NE2 2.83Å; E219-H223 WeakPolarHBondContact O-CB 3.33Å; E219-H223 PolarHBondContact O-CD2 3.09Å; E219-H223 VanDerWaalsContact O-CG 3.26Å; E219-H223 PolarHBondContact O-N 3.31Å; I220-H223 PolarHBondContact O-N 3.38Å; H223-T226 PolarHBondContact O-OG1 3.2Å; H223-L227 WeakPolarHBondContact O-CB 3.49Å; H223-L227 PolarHBondContact O-N 2.79Å
224	Y	98.6	Very high	97.9	Very high	2 Å²	2	44.6 Å²	44.6	1%	0.008	22%	0.216	C	C	.	.	H	α-helix	trans	-62.7	-43.2	174.7	-77.4	-58.3	0	0	0	112.1	F27 R30 L125 E128 I220 R221 N222 H228	F27-Y224 HydrophobicContact CB-CD1 4.39Å; F27-Y224 AromaticContact CD1-CD1 3.56Å; F27-Y224 HydrophobicContact CD1-CD1 3.56Å; F27-Y224 AromaticContact CD1-CE1 3.74Å; F27-Y224 HydrophobicContact CD1-CE1 3.74Å; F27-Y224 HydrophobicContact CD2-CD1 4.34Å; F27-Y224 AromaticContact CE1-CD1 3.77Å; F27-Y224 HydrophobicContact CE1-CD1 3.77Å; F27-Y224 AromaticContact CE1-CE1 3.65Å; F27-Y224 HydrophobicContact CE1-CE1 3.65Å; F27-Y224 AromaticContact CG-CD1 3.85Å; F27-Y224 HydrophobicContact CG-CD1 3.85Å; F27-Y224 HydrophobicContact CG-CE1 4.49Å; F27-Y224 HydrophobicContact CZ-CD1 4.26Å; F27-Y224 HydrophobicContact CZ-CE1 4.36Å; R30-Y224 HydrophobicContact CB-CD1 4Å; R30-Y224 HydrophobicContact CB-CD2 3.49Å; R30-Y224 VanDerWaalsContact CB-CD2 3.49Å; R30-Y224 HydrophobicContact CB-CE1 4.08Å; R30-Y224 HydrophobicContact CB-CE2 3.58Å; R30-Y224 HydrophobicContact CB-CG 3.7Å; R30-Y224 HydrophobicContact CG-CD1 4.22Å; R30-Y224 HydrophobicContact CG-CD2 4.27Å; R30-Y224 HydrophobicContact CG-CE1 3.88Å; R30-Y224 HydrophobicContact CG-CE2 3.93Å; R30-Y224 HydrophobicContact CG-CG 4.4Å; L125-Y224 WeakPolarHBondContact CA-OH 3.42Å; L125-Y224 HydrophobicContact CB-CE2 4.37Å; L125-Y224 HydrophobicContact CD1-CD1 4.07Å; L125-Y224 HydrophobicContact CD1-CD2 4.13Å; L125-Y224 HydrophobicContact CD1-CE1 3.74Å; L125-Y224 HydrophobicContact CD1-CE2 3.8Å; L125-Y224 HydrophobicContact CD1-CG 4.26Å; L125-Y224 PolarHBondContact N-OH 2.98Å; E128-Y224 WeakPolarHBondContact OE2-CE1 3.26Å; E128-Y224 PolarHBondContact OE2-OH 3.13Å; I220-Y224 HydrophobicContact CG2-CD2 3.8Å; I220-Y224 HydrophobicContact CG2-CE2 3.49Å; I220-Y224 VanDerWaalsContact CG2-CE2 3.49Å; I220-Y224 WeakPolarHBondContact O-CD2 3.46Å; I220-Y224 PolarHBondContact O-N 3.37Å; I220-Y224 VanDerWaalsContact O-N 3.13Å; R221-Y224 PolarHBondContact O-N 3.33Å; N222-Y224 PolarHBondContact O-N 2.89Å; Y224-H228 WeakPolarHBondContact O-CB 3.04Å; Y224-H228 PolarHBondContact O-N 3.09Å
225	A	98.4	Very high	98	Very high	40 Å²	40	42.6 Å²	42.6	33%	0.331	21%	0.211	S	C	.	.	H	α-helix	trans	-66.4	-46.4	-179.2	0	0	0	0	0	112.4	V31 R221 N222 D229	V31-A225 HydrophobicContact CG2-CB 3.93Å; R221-A225 WeakPolarHBondContact O-CB 3.17Å; R221-A225 PolarHBondContact O-N 3.45Å; N222-A225 PolarHBondContact O-N 3.27Å; N222-A225 VanDerWaalsContact O-N 3.15Å; A225-D229 VanDerWaalsContact O-CB 3.3Å; A225-D229 WeakPolarHBondContact O-CB 3.34Å; A225-D229 PolarHBondContact O-N 3.32Å
226	T	98	Very high	97.9	Very high	64 Å²	64	41.9 Å²	41.9	39%	0.393	21%	0.214	S	C	.	.	H	α-helix	trans	-69.9	-44.1	-178.8	58.5	0	0	0	0	111.5	N222 H223 D229 I230	N222-T226 WeakPolarHBondContact O-CG2 3.12Å; N222-T226 PolarHBondContact O-N 2.91Å; N222-T226 PolarHBondContact O-OG1 3.07Å; N222-T226 VanDerWaalsContact O-OG1 3.12Å; H223-T226 PolarHBondContact O-OG1 3.2Å; T226-D229 PolarHBondContact O-N 3.14Å; T226-I230 WeakPolarHBondContact O-CG2 3.36Å; T226-I230 PolarHBondContact O-N 3.37Å
227	L	97.9	Very high	97.7	Very high	2 Å²	2	45.9 Å²	45.9	1%	0.01	23%	0.23	C	C	.	.	H	α-helix	trans	-66.2	-39.2	179	-171.4	62.4	0	0	0	111.3	F27 V132 E160 I164 H223 I230 I231	F27-L227 HydrophobicContact CE2-CB 4.21Å; F27-L227 HydrophobicContact CE2-CD2 3.57Å; F27-L227 HydrophobicContact CE2-CG 3.85Å; F27-L227 HydrophobicContact CZ-CD2 3.95Å; V132-L227 HydrophobicContact CG1-CD2 4.36Å; V132-L227 HydrophobicContact CG2-CD2 4.4Å; E160-L227 HydrophobicContact CB-CD1 4.45Å; E160-L227 HydrophobicContact CG-CD1 4.01Å; I164-L227 HydrophobicContact CD1-CB 4.06Å; I164-L227 HydrophobicContact CD1-CD1 4.43Å; I164-L227 HydrophobicContact CD1-CD2 3.78Å; I164-L227 HydrophobicContact CD1-CG 4.31Å; H223-L227 WeakPolarHBondContact O-CB 3.49Å; H223-L227 PolarHBondContact O-N 2.79Å; L227-I230 HydrophobicContact CD1-CG2 4.36Å; L227-I230 WeakPolarHBondContact O-CG2 3.06Å; L227-I231 HydrophobicContact CD1-CD1 3.79Å; L227-I231 HydrophobicContact CD1-CG1 4.34Å; L227-I231 HydrophobicContact CG-CD1 3.77Å; L227-I231 VanDerWaalsContact O-CB 3.28Å; L227-I231 WeakPolarHBondContact O-CB 2.95Å; L227-I231 VanDerWaalsContact O-CD1 3.31Å; L227-I231 WeakPolarHBondContact O-CD1 3.39Å; L227-I231 WeakPolarHBondContact O-CG1 3.3Å; L227-I231 PolarHBondContact O-N 3.05Å
228	H	98.2	Very high	97.5	Very high	50 Å²	50	45.9 Å²	45.9	23%	0.231	23%	0.23	C	C	.	.	H	α-helix	trans	-58	-55.1	169.8	172.2	-81.4	0	0	0	111.1	V23 F27 P28 Y224 I230 I231 I232	V23-H228 PolarHBondContact O-CD2 3.27Å; F27-H228 HydrophobicContact CB-CB 4.08Å; F27-H228 HydrophobicContact CD2-CB 4.15Å; P28-H228 WeakPolarHBondContact CG-NE2 3.39Å; Y224-H228 WeakPolarHBondContact O-CB 3.04Å; Y224-H228 PolarHBondContact O-N 3.09Å; H228-I230 PolarHBondContact O-N 2.93Å; H228-I231 PolarHBondContact O-N 3Å; H228-I232 VanDerWaalsContact O-CG1 3.29Å; H228-I232 WeakPolarHBondContact O-CG1 3.33Å; H228-I232 PolarHBondContact O-N 3.33Å
229	D	98.3	Very high	97.4	Very high	73 Å²	73	47.4 Å²	47.4	39%	0.39	24%	0.235	S	C	.	.	H	α-helix	trans	-59.1	-47.7	-174.3	178.7	66.6	0	0	0	113	A225 T226 I231 I232 K233	A225-D229 VanDerWaalsContact O-CB 3.3Å; A225-D229 WeakPolarHBondContact O-CB 3.34Å; A225-D229 PolarHBondContact O-N 3.32Å; T226-D229 PolarHBondContact O-N 3.14Å; D229-I231 VanDerWaalsContact C-N 3.33Å; D229-I231 PolarHBondContact O-N 3.08Å; D229-I232 PolarHBondContact O-N 2.78Å; D229-K233 VanDerWaalsContact O-CG 3.31Å; D229-K233 WeakPolarHBondContact O-CG 3.27Å; D229-K233 PolarHBondContact O-N 2.9Å; D229-K233 VanDerWaalsContact O-N 3.14Å; D229-K233 WeakPolarHBondContact OD1-CE 3.46Å; D229-K233 IonicContact OD1-NZ 3.92Å; D229-K233 PolarHBondContact OD1-NZ 2.6Å; D229-K233 VanDerWaalsContact OD1-NZ 3.1Å; D229-K233 WeakPolarHBondContact OD2-CE 3.49Å; D229-K233 IonicContact OD2-NZ 3.74Å; D229-K233 PolarHBondContact OD2-NZ 3.31Å
230	I	97.6	Very high	97.1	Very high	39 Å²	39	52.4 Å²	52.4	20%	0.2	26%	0.26	C	S	.	.	H	α-helix	trans	-65.1	-37.1	179	-166.6	174.2	0	0	0	112	I157 T226 L227 H228 N234	I157-I230 HydrophobicContact CG1-CD1 4.34Å; I157-I230 HydrophobicContact CG1-CG1 4.37Å; T226-I230 WeakPolarHBondContact O-CG2 3.36Å; T226-I230 PolarHBondContact O-N 3.37Å; L227-I230 HydrophobicContact CD1-CG2 4.36Å; L227-I230 WeakPolarHBondContact O-CG2 3.06Å; H228-I230 PolarHBondContact O-N 2.93Å; I230-N234 PolarHBondContact O-N 3.39Å; I230-N234 PolarHBondContact O-ND2 3.22Å
231	I	97.9	Very high	96.8	Very high	0 Å²	0	53 Å²	53	0%	0	26%	0.263	C	S	.	.	H	α-helix	trans	-69.7	-46.3	179.6	-73.1	173.2	0	0	0	111	V23 V132 W135 I157 L227 H228 D229 K233 N234 L235 I238	V23-I231 HydrophobicContact CB-CD1 4.46Å; V23-I231 HydrophobicContact CB-CG2 4.11Å; V23-I231 HydrophobicContact CG1-CD1 3.73Å; V23-I231 HydrophobicContact CG1-CG2 4.34Å; V23-I231 HydrophobicContact CG2-CG2 3.84Å; V132-I231 HydrophobicContact CG1-CD1 3.67Å; W135-I231 HydrophobicContact CH2-CG2 3.87Å; W135-I231 HydrophobicContact CZ3-CD1 4.32Å; W135-I231 HydrophobicContact CZ3-CG2 3.84Å; I157-I231 HydrophobicContact CG2-CD1 4.2Å; I157-I231 HydrophobicContact CG2-CG1 3.86Å; L227-I231 HydrophobicContact CD1-CD1 3.79Å; L227-I231 HydrophobicContact CD1-CG1 4.34Å; L227-I231 HydrophobicContact CG-CD1 3.77Å; L227-I231 VanDerWaalsContact O-CB 3.28Å; L227-I231 WeakPolarHBondContact O-CB 2.95Å; L227-I231 VanDerWaalsContact O-CD1 3.31Å; L227-I231 WeakPolarHBondContact O-CD1 3.39Å; L227-I231 WeakPolarHBondContact O-CG1 3.3Å; L227-I231 PolarHBondContact O-N 3.05Å; H228-I231 PolarHBondContact O-N 3Å; D229-I231 VanDerWaalsContact C-N 3.33Å; D229-I231 PolarHBondContact O-N 3.08Å; I231-K233 VanDerWaalsContact C-N 3.3Å; I231-K233 PolarHBondContact O-N 3.09Å; I231-N234 CarbonylContact O-C 3.58Å; I231-N234 PolarHBondContact O-N 3.45Å; I231-N234 VanDerWaalsContact O-N 3.13Å; I231-L235 HydrophobicContact CG2-CD1 4.4Å; I231-L235 WeakPolarHBondContact O-CA 3.42Å; I231-L235 PolarHBondContact O-N 3.02Å; I231-I238 HydrophobicContact CB-CD1 4.18Å; I231-I238 HydrophobicContact CG1-CD1 4.19Å; I231-I238 HydrophobicContact CG2-CD1 3.81Å
232	I	97.7	Very high	96.4	Very high	71 Å²	71	51.9 Å²	51.9	36%	0.364	26%	0.259	S	S	.	.	H	α-helix	trans	-59.6	-43	178.7	-66.5	-59.1	0	0	0	111.1	L24 H228 D229 N234	L24-I232 HydrophobicContact CD2-CD1 3.25Å; H228-I232 VanDerWaalsContact O-CG1 3.29Å; H228-I232 WeakPolarHBondContact O-CG1 3.33Å; H228-I232 PolarHBondContact O-N 3.33Å; D229-I232 PolarHBondContact O-N 2.78Å; I232-N234 PolarHBondContact O-N 3.07Å
233	K	97.8	Very high	95.4	Very high	135 Å²	135	51.6 Å²	51.6	59%	0.587	26%	0.262	S	S	*	.	H	α-helix	trans	-62.6	-25.2	179.1	-75.7	170	178.4	168.2	0	113.8	D229 I231	D229-K233 VanDerWaalsContact O-CG 3.31Å; D229-K233 WeakPolarHBondContact O-CG 3.27Å; D229-K233 PolarHBondContact O-N 2.9Å; D229-K233 VanDerWaalsContact O-N 3.14Å; D229-K233 WeakPolarHBondContact OD1-CE 3.46Å; D229-K233 IonicContact OD1-NZ 3.92Å; D229-K233 PolarHBondContact OD1-NZ 2.6Å; D229-K233 VanDerWaalsContact OD1-NZ 3.1Å; D229-K233 WeakPolarHBondContact OD2-CE 3.49Å; D229-K233 IonicContact OD2-NZ 3.74Å; D229-K233 PolarHBondContact OD2-NZ 3.31Å; I231-K233 VanDerWaalsContact C-N 3.3Å; I231-K233 PolarHBondContact O-N 3.09Å
234	N	97.4	Very high	93.9	Very high	42 Å²	42	57 Å²	57	23%	0.225	29%	0.291	C	S	.	.	T	Hydrogen-bonded Turn	trans	-121.7	15.6	-172.6	-65.5	-75.3	0	0	0	113.1	I153 I157 I230 I231 I232 D236 R237 I238	I153-N234 HydrophobicContact CG2-CB 3.74Å; I157-N234 HydrophobicContact CD1-CB 4.17Å; I230-N234 PolarHBondContact O-N 3.39Å; I230-N234 PolarHBondContact O-ND2 3.22Å; I231-N234 CarbonylContact O-C 3.58Å; I231-N234 PolarHBondContact O-N 3.45Å; I231-N234 VanDerWaalsContact O-N 3.13Å; I232-N234 PolarHBondContact O-N 3.07Å; N234-D236 VanDerWaalsContact C-N 3.26Å; N234-D236 PolarHBondContact O-N 3.18Å; N234-R237 PolarHBondContact O-N 3.32Å; N234-I238 HydrophobicContact CB-CD1 4.49Å; N234-I238 WeakPolarHBondContact O-CG1 3.38Å; N234-I238 PolarHBondContact O-N 3.39Å
235	L	96.5	Very high	91.8	Very high	37 Å²	37	62.8 Å²	62.8	19%	0.194	32%	0.322	C	S	.	.	H	α-helix	trans	-59.5	-36.3	-169.6	-173.6	64.1	0	0	0	112.9	L24 W135 I231 I238 K239	L24-L235 HydrophobicContact CD2-CD2 4.26Å; W135-L235 HydrophobicContact CH2-CD1 3.78Å; W135-L235 HydrophobicContact CZ2-CD1 4.06Å; I231-L235 HydrophobicContact CG2-CD1 4.4Å; I231-L235 WeakPolarHBondContact O-CA 3.42Å; I231-L235 PolarHBondContact O-N 3.02Å; L235-I238 PolarHBondContact O-N 3.04Å; L235-K239 HydrophobicContact CD1-CD 4.22Å; L235-K239 HydrophobicContact CG-CD 4.24Å; L235-K239 WeakPolarHBondContact O-CG 3.29Å; L235-K239 PolarHBondContact O-N 2.81Å; L235-K239 VanDerWaalsContact O-N 3.1Å
236	D	94.9	Very high	89.5	Confident	94 Å²	94	64.2 Å²	64.2	50%	0.503	33%	0.334	S	S	.	.	H	α-helix	trans	-60.2	-45.2	174.9	66.8	-49.6	0	0	0	111.4	N234 K239 M240	N234-D236 VanDerWaalsContact C-N 3.26Å; N234-D236 PolarHBondContact O-N 3.18Å; D236-K239 PolarHBondContact O-N 2.97Å; D236-M240 CarbonylContact O-C 3.45Å; D236-M240 WeakPolarHBondContact O-CA 3.04Å; D236-M240 PolarHBondContact O-N 3.25Å
237	R	94.1	Very high	87.2	Confident	84 Å²	84	67.5 Å²	67.5	32%	0.317	35%	0.348	S	S	.	.	H	α-helix	trans	-75.2	-30	-179.8	-59.2	-55.5	174.5	163.1	3.2	113.1	I153 N234 P241	I153-R237 HydrophobicContact CD1-CB 4.03Å; I153-R237 HydrophobicContact CD1-CG 3.92Å; I153-R237 HydrophobicContact CG2-CB 4.26Å; N234-R237 PolarHBondContact O-N 3.32Å; R237-P241 WeakPolarHBondContact O-CA 3.46Å; R237-P241 WeakPolarHBondContact O-CB 3.16Å
238	I	94.9	Very high	84.7	Confident	0 Å²	0	74.2 Å²	74.2	0%	0	38%	0.384	C	S	.	.	H	α-helix	trans	-64.8	-45.2	172.7	-64.5	164.3	0	0	0	110.3	W135 V136 N139 Q154 I157 I231 N234 L235	W135-I238 HydrophobicContact CH2-CG2 4.09Å; W135-I238 HydrophobicContact CZ2-CG2 4.06Å; V136-I238 HydrophobicContact CG2-CG2 4.1Å; N139-I238 VanDerWaalsContact CB-O 3.23Å; N139-I238 WeakPolarHBondContact CB-O 3.48Å; Q154-I238 PolarHBondContact NE2-O 3.25Å; I157-I238 HydrophobicContact CD1-CD1 3.35Å; I157-I238 HydrophobicContact CD1-CG1 3.49Å; I157-I238 VanDerWaalsContact CD1-CG1 3.49Å; I231-I238 HydrophobicContact CB-CD1 4.18Å; I231-I238 HydrophobicContact CG1-CD1 4.19Å; I231-I238 HydrophobicContact CG2-CD1 3.81Å; N234-I238 HydrophobicContact CB-CD1 4.49Å; N234-I238 WeakPolarHBondContact O-CG1 3.38Å; N234-I238 PolarHBondContact O-N 3.39Å; L235-I238 PolarHBondContact O-N 3.04Å
239	K	94.5	Very high	82	Confident	86 Å²	86	79.8 Å²	79.8	37%	0.374	41%	0.412	S	S	.	.	H	α-helix	trans	-80.6	-36	-177.3	-66.5	178.7	66.9	159.6	0	112.7	E20 L235 D236	E20-K239 IonicContact OE1-NZ 3.81Å; E20-K239 PolarHBondContact OE1-NZ 2.82Å; E20-K239 WeakPolarHBondContact OE2-CE 3.49Å; E20-K239 IonicContact OE2-NZ 2.8Å; E20-K239 PolarHBondContact OE2-NZ 3.48Å; L235-K239 HydrophobicContact CD1-CD 4.22Å; L235-K239 HydrophobicContact CG-CD 4.24Å; L235-K239 WeakPolarHBondContact O-CG 3.29Å; L235-K239 PolarHBondContact O-N 2.81Å; L235-K239 VanDerWaalsContact O-N 3.1Å; D236-K239 PolarHBondContact O-N 2.97Å
240	M	92.8	Very high	79.2	Confident	145 Å²	145	90.3 Å²	90.3	71%	0.714	45%	0.448	S	S	*	.			trans	-137.6	77.8	-176.5	-63.1	-173	-174.3	0	0	110.6	D236 R242	D236-M240 CarbonylContact O-C 3.45Å; D236-M240 WeakPolarHBondContact O-CA 3.04Å; D236-M240 PolarHBondContact O-N 3.25Å; M240-R242 PolarHBondContact O-N 3.01Å
241	P	92.5	Very high	78.2	Confident	11 Å²	11	92.9 Å²	92.9	7%	0.071	46%	0.461	C	S	.	.			trans	-69.3	-20.7	-174.4	25.4	-34.3	0	0	0	113.7	P141 G150 V151 R237	P141-P241 HydrophobicContact CG-CG 3.83Å; G150-P241 VanDerWaalsContact C-CB 3.46Å; G150-P241 WeakPolarHBondContact CA-O 3.24Å; V151-P241 HydrophobicContact CG2-CB 4.27Å; R237-P241 WeakPolarHBondContact O-CA 3.46Å; R237-P241 WeakPolarHBondContact O-CB 3.16Å
242	R	89.6	Confident	77.2	Confident	44 Å²	44	97.8 Å²	97.8	17%	0.166	49%	0.485	C	S	.	.	S	Bend	trans	-110	128.3	179.8	-67.9	-173.3	177.2	143.1	10.2	110.7	R142 E144 N148 M240	R142-R242 PolarHBondContact O-NH1 3.43Å; R142-R242 PolarHBondContact O-NH2 3.12Å; E144-R242 VanDerWaalsContact CD-CZ 3.49Å; E144-R242 IonicContact OE1-NH1 3.15Å; E144-R242 PolarHBondContact OE1-NH1 3.27Å; E144-R242 IonicContact OE2-CZ 2.73Å; E144-R242 IonicContact OE2-NE 2.76Å; E144-R242 PolarHBondContact OE2-NE 3.27Å; E144-R242 IonicContact OE2-NH1 3.44Å; E144-R242 PolarHBondContact OE2-NH1 3.01Å; E144-R242 IonicContact OE2-NH2 3.95Å; N148-R242 PolarHBondContact OD1-NH2 3.03Å; M240-R242 PolarHBondContact O-N 3.01Å
243	S	78	Confident	76.1	Confident	48 Å²	48	99.3 Å²	99.3	34%	0.336	49%	0.492	S	S	.	.			trans	-68.7	137.1	165.6	53.4	0	0	0	0	110.2	N245	S243-N245 PolarHBondContact O-N 3.47Å
244	N	65.7	Low	74.8	Confident	131 Å²	131	97.2 Å²	97.2	70%	0.701	49%	0.486	S	S	*	.	G	3₁₀ helix	trans	-60.6	2.2	176.6	-83.4	-13.8	0	0	0	115.2	A246 I247	N244-A246 PolarHBondContact O-N 2.77Å; N244-I247 PolarHBondContact O-N 3.48Å
245	N	55.2	Low	73.4	Confident	122 Å²	122	100.6 Å²	100.6	65%	0.652	50%	0.502	S	S	*	.	G	3₁₀ helix	trans	-64.9	-10.1	-178.8	-65.5	-7.4	0	0	0	114	S243 I247	S243-N245 PolarHBondContact O-N 3.47Å; N245-I247 VanDerWaalsContact C-N 3.34Å
246	A	49.8	Very low	71.9	Confident	71 Å²	71	104.9 Å²	104.9	59%	0.587	52%	0.523	S	S	*	.	G	3₁₀ helix	trans	-76.9	-14.5	175.5	0	0	0	0	0	114.2	N244	N244-A246 PolarHBondContact O-N 2.77Å
247	I	50.4	Low	70.2	Confident	132 Å²	132	105.6 Å²	105.6	68%	0.677	52%	0.524	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88.4	-14.2	-176.8	-64	174.4	0	0	0	112.5	N244 N245	N244-I247 PolarHBondContact O-N 3.48Å; N245-I247 VanDerWaalsContact C-N 3.34Å
248	N	45.6	Very low	68.4	Low	143 Å²	143	107.3 Å²	107.3	77%	0.765	54%	0.54	S	S	*	.	T	Hydrogen-bonded Turn	trans	-100.8	21.4	-175.8	-73	-12.7	0	0	0	115
249	M	42	Very low	66.2	Low	168 Å²	168	116.3 Å²	116.3	83%	0.828	59%	0.585	S	S	*	*			trans	-111.6	20	178.2	-74.2	-158.9	-175.2	0	0	114.9
250	Y	37.9	Very low	63.6	Low	294 Å²	294	119 Å²	119	100%	1.153	60%	0.604	S	S	*	*			trans	-129.8	0	168	-76.3	-74.1	0	0	0	111.4

Retrieved 250 of 250 residues in 171.7 ms (Link to these results)

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