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Ubiquinone biosynthesis protein

Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.

AlphaFold DB (A0A5K4EDC0), UniProt , Accession A0A3Q0KEM3, Species SCHMA (Schistosoma mansoni, Blood fluke), Gene n/a, Length 307 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	38.1	Very low	38.3	Very low	236 Å²	236	151.5 Å²	151.5	100%	1.163	82%	0.818	S	S	*	*				0	115.1	0	-65.9	177.4	170	0	0	106
2	I	43.3	Very low	38.3	Very low	167 Å²	167	153.8 Å²	153.8	86%	0.856	82%	0.82	S	S	*	*			cis	-152.7	120.8	18.8	-83.7	136.4	0	0	0	104.5
3	G	37.2	Very low	38.1	Very low	65 Å²	65	150.6 Å²	150.6	67%	0.67	81%	0.813	S	S	*	*				76	99.9	119.3	0	0	0	0	0	114.4
4	R	37.3	Very low	38	Very low	238 Å²	238	153.9 Å²	153.9	90%	0.898	82%	0.816	S	S	*	*				54.7	135.7	92.2	-78.4	-168.2	168.5	-177.3	-3.1	112.3
5	F	36.2	Very low	37.7	Very low	157 Å²	157	154.3 Å²	154.3	69%	0.689	82%	0.817	S	S	*	*			cis	-171.1	133.4	22.8	-148.4	-121	0	0	0	105.1
6	V	37.7	Very low	37.2	Very low	102 Å²	102	151.5 Å²	151.5	62%	0.618	81%	0.813	S	S	*	*				47.5	125.7	115.8	-167.3	0	0	0	0	115.7
7	I	39.7	Very low	36.8	Very low	142 Å²	142	149.1 Å²	149.1	73%	0.728	81%	0.81	S	S	*	*				175.6	109.5	119	-85.8	179.6	0	0	0	109.8
8	L	38.2	Very low	36.5	Very low	158 Å²	158	146.7 Å²	146.7	83%	0.827	81%	0.807	S	S	*	*			trans	44.3	120.1	134.7	-66.9	137.1	0	0	0	121.1
9	G	33.8	Very low	36.4	Very low	75 Å²	75	145.7 Å²	145.7	77%	0.773	81%	0.805	S	S	*	*				84.2	81.8	121.1	0	0	0	0	0	117	R11	G9-R11 PolarHBondContact O-N 3.43Å
10	G	42.4	Very low	36.2	Very low	84 Å²	84	144.3 Å²	144.3	87%	0.866	81%	0.806	S	S	*	*			trans	-62.4	125	174.2	0	0	0	0	0	114.1
11	R	37.3	Very low	35.7	Very low	242 Å²	242	143.1 Å²	143.1	91%	0.913	81%	0.807	S	S	*	*			trans	-46.7	136.7	164.9	-85.5	168.1	164.8	174.4	-4.5	113.3	G9	G9-R11 PolarHBondContact O-N 3.43Å
12	Q	37.8	Very low	35.4	Very low	179 Å²	179	136.9 Å²	136.9	84%	0.836	79%	0.793	S	S	*	*			trans	-125.5	140.9	145.8	-77.9	-69.2	-31.2	0	0	108.3
13	P	36.2	Very low	34.6	Very low	113 Å²	113	140.8 Å²	140.8	73%	0.734	80%	0.797	S	S	*	*			trans	-87.4	152.2	-166.5	34.5	-32.5	0	0	0	113.1
14	K	37.1	Very low	34.3	Very low	196 Å²	196	143.2 Å²	143.2	85%	0.852	80%	0.804	S	S	*	*			trans	-73.2	135	162.8	-66	-173.9	173.7	-177.2	0	109.5
15	L	33.8	Very low	34	Very low	160 Å²	160	136.7 Å²	136.7	84%	0.838	80%	0.795	S	S	*	*				172	132	118.5	-108.6	101.5	0	0	0	112.2
16	C	28.6	Very low	33.9	Very low	110 Å²	110	134.6 Å²	134.6	74%	0.743	80%	0.799	S	S	*	*			trans	60.5	112.4	151.2	-77.1	0	0	0	0	124
17	S	31.5	Very low	33.9	Very low	110 Å²	110	138.9 Å²	138.9	77%	0.769	81%	0.81	S	S	*	*				94.6	121.1	127.4	72	0	0	0	0	121.4
18	S	31.2	Very low	33.8	Very low	107 Å²	107	140.7 Å²	140.7	75%	0.748	81%	0.809	S	S	*	*			trans	93.4	114.4	146.5	79.8	0	0	0	0	120.5
19	V	33.9	Very low	33.6	Very low	127 Å²	127	144.1 Å²	144.1	77%	0.77	81%	0.811	S	S	*	*			trans	88	105.3	130.9	178.8	0	0	0	0	119.5
20	S	31.9	Very low	33.4	Very low	117 Å²	117	148.9 Å²	148.9	82%	0.818	82%	0.815	S	S	*	*			trans	79.9	121.8	133.3	-55.9	0	0	0	0	122.2
21	S	26.9	Very low	33.2	Very low	121 Å²	121	149.5 Å²	149.5	85%	0.846	80%	0.802	S	S	*	*			trans	-93.1	137	176.4	131.6	0	0	0	0	111.6
22	A	31.6	Very low	33.1	Very low	104 Å²	104	141.5 Å²	141.5	86%	0.86	78%	0.78	S	S	*	*			trans	-146.6	116.9	153.6	0	0	0	0	0	110.3
23	R	26.6	Very low	33.2	Very low	250 Å²	250	138.6 Å²	138.6	94%	0.943	77%	0.769	S	S	*	*			trans	-145.4	145.1	170	-146.5	178.2	-164.5	-151.6	3.8	108.8
24	S	30.2	Very low	33.3	Very low	115 Å²	115	137.6 Å²	137.6	80%	0.804	76%	0.76	S	S	*	*			trans	105.2	95.3	173.1	-156.1	0	0	0	0	113.8
25	S	31.6	Very low	33.3	Very low	102 Å²	102	130.8 Å²	130.8	71%	0.713	74%	0.737	S	S	*	*				95.8	106	52.9	-166.9	0	0	0	0	114
26	S	34.9	Very low	33.4	Very low	112 Å²	112	126.9 Å²	126.9	78%	0.783	72%	0.724	S	S	*	*	S	Bend	trans	77.4	18.7	135.8	-153.1	0	0	0	0	123
27	K	38	Very low	34.3	Very low	192 Å²	192	127.8 Å²	127.8	84%	0.835	72%	0.719	S	S	*	*	S	Bend	trans	-115.6	0.7	168.6	-71.4	-173.4	179.1	-178	0	116.2
28	Y	36	Very low	34.9	Very low	181 Å²	181	126.7 Å²	126.7	71%	0.71	70%	0.704	S	S	*	*			trans	-106.5	2.9	-170.2	-67	-80.3	0	0	0	115.9	M30 V31 T32	Y28-M30 PolarHBondContact O-N 2.73Å; Y28-V31 PolarHBondContact O-N 3.35Å; Y28-T32 PolarHBondContact O-N 2.96Å; Y28-T32 PolarHBondContact O-OG1 2.69Å
29	R	33.7	Very low	35.1	Very low	230 Å²	230	128.9 Å²	128.9	87%	0.868	70%	0.702	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72.6	-21.8	-169.1	-112.7	-178.5	176	-162.9	-2	116
30	M	31.1	Very low	35.5	Very low	174 Å²	174	125.6 Å²	125.6	86%	0.857	68%	0.682	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87	-25.2	175.2	-115.5	-119.9	-162.3	0	0	112.8	Y28	Y28-M30 PolarHBondContact O-N 2.73Å
31	V	38.2	Very low	35.6	Very low	98 Å²	98	123.7 Å²	123.7	59%	0.594	67%	0.667	S	S	*	*	H	α-helix	trans	-78.3	-23.5	178.8	178.8	0	0	0	0	111.5	Y28 I33 S35	Y28-V31 PolarHBondContact O-N 3.35Å; V31-I33 PolarHBondContact O-N 2.9Å; V31-S35 WeakPolarHBondContact O-CB 3.41Å; V31-S35 PolarHBondContact O-N 3.49Å; V31-S35 VanDerWaalsContact O-N 3.16Å
32	T	34.5	Very low	36.1	Very low	73 Å²	73	124.5 Å²	124.5	45%	0.448	66%	0.661	S	S	.	*	H	α-helix	trans	-67.1	-31.1	178.8	-48.4	0	0	0	0	113.2	Y28 S36	Y28-T32 PolarHBondContact O-N 2.96Å; Y28-T32 PolarHBondContact O-OG1 2.69Å; T32-S36 WeakPolarHBondContact O-CB 3.31Å; T32-S36 PolarHBondContact O-N 3.25Å; T32-S36 PolarHBondContact O-OG 2.94Å
33	I	40	Very low	36.2	Very low	118 Å²	118	127.3 Å²	127.3	61%	0.605	66%	0.657	S	S	*	*	H	α-helix	trans	-71.5	-38.6	-175.7	-60	177.5	0	0	0	111.7	V31 I37	V31-I33 PolarHBondContact O-N 2.9Å; I33-I37 WeakPolarHBondContact O-CG1 3.44Å
34	V	39.2	Very low	36.6	Very low	93 Å²	93	124.3 Å²	124.3	56%	0.564	65%	0.645	S	S	*	*	H	α-helix	trans	-79.1	-34	177.8	-173.7	0	0	0	0	111.1	I38	V34-I38 HydrophobicContact CG1-CD1 3.75Å; V34-I38 VanDerWaalsContact O-CG1 3.31Å; V34-I38 WeakPolarHBondContact O-CG1 3.15Å; V34-I38 PolarHBondContact O-N 3.45Å
35	S	35.1	Very low	36.8	Very low	53 Å²	53	123.6 Å²	123.6	37%	0.371	63%	0.632	S	S	.	*	H	α-helix	trans	-71.3	-32.8	173.8	-170.8	0	0	0	0	112.7	V31 I37 I38 H39	V31-S35 WeakPolarHBondContact O-CB 3.41Å; V31-S35 PolarHBondContact O-N 3.49Å; V31-S35 VanDerWaalsContact O-N 3.16Å; S35-I37 VanDerWaalsContact C-N 3.28Å; S35-I37 PolarHBondContact O-N 3.32Å; S35-I38 PolarHBondContact O-N 2.99Å; S35-H39 WeakPolarHBondContact O-CA 3.46Å; S35-H39 WeakPolarHBondContact O-CB 3.41Å; S35-H39 PolarHBondContact O-N 3.24Å
36	S	37.6	Very low	36.9	Very low	78 Å²	78	122.5 Å²	122.5	55%	0.545	62%	0.623	S	S	.	*	H	α-helix	trans	-71.9	-21.7	179.6	-72.9	0	0	0	0	113.5	T32	T32-S36 WeakPolarHBondContact O-CB 3.31Å; T32-S36 PolarHBondContact O-N 3.25Å; T32-S36 PolarHBondContact O-OG 2.94Å
37	I	45.8	Very low	36.6	Very low	128 Å²	128	124.4 Å²	124.4	66%	0.656	62%	0.62	S	S	*	*	H	α-helix	trans	-86.2	-30.3	176	-62.1	170.2	0	0	0	110.9	I33 S35	I33-I37 WeakPolarHBondContact O-CG1 3.44Å; S35-I37 VanDerWaalsContact C-N 3.28Å; S35-I37 PolarHBondContact O-N 3.32Å
38	I	45.1	Very low	36.4	Very low	87 Å²	87	120.2 Å²	120.2	45%	0.446	62%	0.615	S	S	.	*	H	α-helix	trans	-99.3	-18.6	-174.1	-57.9	173.3	0	0	0	112.5	V34 S35 W231	V34-I38 HydrophobicContact CG1-CD1 3.75Å; V34-I38 VanDerWaalsContact O-CG1 3.31Å; V34-I38 WeakPolarHBondContact O-CG1 3.15Å; V34-I38 PolarHBondContact O-N 3.45Å; S35-I38 PolarHBondContact O-N 2.99Å; I38-W231 HydrophobicContact CG2-CH2 3.86Å
39	H	35.7	Very low	36.2	Very low	153 Å²	153	116.6 Å²	116.6	71%	0.708	62%	0.616	S	S	*	*			trans	-103.4	41.4	178.7	-124.4	53.7	0	0	0	111.9	S35	S35-H39 WeakPolarHBondContact O-CA 3.46Å; S35-H39 WeakPolarHBondContact O-CB 3.41Å; S35-H39 PolarHBondContact O-N 3.24Å
40	V	42.9	Very low	36	Very low	58 Å²	58	108.5 Å²	108.5	35%	0.352	60%	0.595	S	S	.	*	S	Bend	trans	-75.9	120.3	156.5	-178.4	0	0	0	0	105.9	L42 R44 L45	V40-L42 PolarHBondContact O-N 2.91Å; V40-L42 VanDerWaalsContact O-N 3.07Å; V40-R44 HydrophobicContact CG1-CB 4.36Å; V40-L45 HydrophobicContact CB-CD1 3.99Å; V40-L45 HydrophobicContact CG1-CD1 3.69Å; V40-L45 HydrophobicContact CG1-CG 3.96Å; V40-L45 HydrophobicContact CG2-CD1 4.46Å
41	P	33.3	Very low	36.1	Very low	77 Å²	77	107.5 Å²	107.5	50%	0.5	59%	0.591	S	S	.	*			trans	-57.9	122.7	175.9	18.3	-22.6	0	0	0	107.7	Q43 R44	P41-Q43 PolarHBondContact O-N 3.03Å; P41-R44 PolarHBondContact O-N 3.44Å
42	L	36.7	Very low	35.8	Very low	138 Å²	138	109.1 Å²	109.1	72%	0.723	60%	0.601	S	S	*	*	T	Hydrogen-bonded Turn	trans	-47.7	-13.4	-179.6	-89.9	150.1	0	0	0	114.5	V40	V40-L42 PolarHBondContact O-N 2.91Å; V40-L42 VanDerWaalsContact O-N 3.07Å
43	Q	35	Very low	35.5	Very low	163 Å²	163	114.2 Å²	114.2	76%	0.762	62%	0.617	S	S	*	*	T	Hydrogen-bonded Turn	trans	-79.5	-16.7	173	-73	178.1	-41.4	0	0	114.9	P41 Q47	P41-Q43 PolarHBondContact O-N 3.03Å; Q43-Q47 WeakPolarHBondContact O-CG 3.46Å
44	R	33.1	Very low	35.1	Very low	187 Å²	187	114.5 Å²	114.5	71%	0.706	63%	0.63	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.5	-18	-177.4	-77.1	-165	-175.5	-159.6	1.7	115.4	V40 P41	V40-R44 HydrophobicContact CG1-CB 4.36Å; P41-R44 PolarHBondContact O-N 3.44Å
45	L	36.2	Very low	34.8	Very low	100 Å²	100	116.2 Å²	116.2	52%	0.524	64%	0.636	S	S	.	*	T	Hydrogen-bonded Turn	trans	-93.2	-27.6	174	-75.6	160.2	0	0	0	112	V40 Q47 S48	V40-L45 HydrophobicContact CB-CD1 3.99Å; V40-L45 HydrophobicContact CG1-CD1 3.69Å; V40-L45 HydrophobicContact CG1-CG 3.96Å; V40-L45 HydrophobicContact CG2-CD1 4.46Å; L45-Q47 PolarHBondContact O-N 2.92Å; L45-S48 PolarHBondContact O-N 3.47Å
46	C	32.1	Very low	34.9	Very low	79 Å²	79	122.2 Å²	122.2	53%	0.534	66%	0.657	S	S	.	*	G	3₁₀ helix	trans	-68.1	-19.8	171.7	-135	0	0	0	0	113	S48	C46-S48 VanDerWaalsContact C-N 3.27Å; C46-S48 PolarHBondContact O-N 3.31Å
47	Q	29.2	Very low	34.7	Very low	153 Å²	153	124.9 Å²	124.9	72%	0.715	67%	0.666	S	S	*	*	G	3₁₀ helix	trans	-74.6	-10.4	173.2	-79.2	-179	-22.7	0	0	114.2	Q43 L45	Q43-Q47 WeakPolarHBondContact O-CG 3.46Å; L45-Q47 PolarHBondContact O-N 2.92Å
48	S	34.3	Very low	33.9	Very low	103 Å²	103	128.1 Å²	128.1	72%	0.72	68%	0.675	S	S	*	*	G	3₁₀ helix	trans	-89.3	-8.6	178.6	-83.5	0	0	0	0	114.4	L45 C46	L45-S48 PolarHBondContact O-N 3.47Å; C46-S48 VanDerWaalsContact C-N 3.27Å; C46-S48 PolarHBondContact O-N 3.31Å
49	S	32.4	Very low	33.2	Very low	105 Å²	105	133 Å²	133	73%	0.734	69%	0.693	S	S	*	*	T	Hydrogen-bonded Turn	trans	-138.3	-3.6	-172.7	-41.8	0	0	0	0	115.4
50	S	27.7	Very low	33.1	Very low	61 Å²	61	133.6 Å²	133.6	43%	0.427	70%	0.696	S	S	.	*			trans	-160	133.9	-178.5	17.2	0	0	0	0	113
51	I	33.8	Very low	32.5	Very low	153 Å²	153	134.2 Å²	134.2	79%	0.785	71%	0.714	S	S	*	*			trans	94.7	96.7	150.2	-56.5	153.2	0	0	0	118.5
52	V	31.8	Very low	32.7	Very low	131 Å²	131	136.2 Å²	136.2	79%	0.794	73%	0.725	S	S	*	*				61.1	117	124.8	-171.9	0	0	0	0	121.1
53	F	28.9	Very low	33	Very low	181 Å²	181	137 Å²	137	79%	0.794	73%	0.725	S	S	*	*			trans	4	124.2	149	-97	-97.9	0	0	0	119.8
54	S	32.4	Very low	33.4	Very low	124 Å²	124	134.3 Å²	134.3	87%	0.867	72%	0.72	S	S	*	*				-161.4	134.5	122.1	-108.2	0	0	0	0	111.3
55	D	31	Very low	33.7	Very low	128 Å²	128	132.3 Å²	132.3	68%	0.684	72%	0.718	S	S	*	*			trans	-52.3	140.9	-172.2	-73.2	-62.4	0	0	0	116.6
56	H	37.2	Very low	33.9	Very low	179 Å²	179	134.3 Å²	134.3	83%	0.829	73%	0.725	S	S	*	*				-170.5	133.5	110.1	-104	-64.7	0	0	0	113.3
57	N	34.9	Very low	34.7	Very low	135 Å²	135	136.2 Å²	136.2	72%	0.722	73%	0.729	S	S	*	*			trans	81.7	94.6	158.3	-84.9	-16.7	0	0	0	120.2
58	K	28.8	Very low	35.8	Very low	195 Å²	195	133 Å²	133	85%	0.848	72%	0.719	S	S	*	*				45	93	124.6	-72.6	-179.7	174.5	176.4	0	116.8
59	F	29.3	Very low	36.9	Very low	191 Å²	191	133.3 Å²	133.3	84%	0.838	71%	0.713	S	S	*	*				-161.9	130.4	129.1	-132.8	-104.8	0	0	0	110.9
60	H	35.1	Very low	38.9	Very low	165 Å²	165	130.8 Å²	130.8	76%	0.764	69%	0.691	S	S	*	*			trans	26.4	108.9	164.5	-82.8	-84.9	0	0	0	120.2
61	G	29.8	Very low	41.5	Very low	71 Å²	71	131.7 Å²	131.7	73%	0.732	70%	0.697	S	S	*	*	S	Bend	trans	-83	115.9	166.1	0	0	0	0	0	112.6
62	T	38	Very low	44	Very low	119 Å²	119	129.4 Å²	129.4	73%	0.73	69%	0.686	S	S	*	*	S	Bend	trans	-169.6	-29.3	145.2	-10.9	0	0	0	0	111.9
63	E	41.7	Very low	46.6	Very low	155 Å²	155	125.4 Å²	125.4	72%	0.724	66%	0.661	S	S	*	*	T	Hydrogen-bonded Turn	trans	-82.7	-20.9	-168.3	-63.3	177.1	168.6	0	0	115.4	H65 E66	E63-H65 VanDerWaalsContact C-N 3.26Å; E63-H65 PolarHBondContact O-N 3.36Å; E63-E66 PolarHBondContact O-N 3.31Å
64	T	43.6	Very low	49.5	Very low	105 Å²	105	119.9 Å²	119.9	64%	0.644	64%	0.636	S	S	*	*	H	α-helix	trans	-69.2	-23.5	-177.9	50.9	0	0	0	0	113.3	V68	T64-V68 WeakPolarHBondContact O-CB 3.3Å; T64-V68 WeakPolarHBondContact O-CG2 3.44Å
65	H	39.9	Very low	52.3	Low	145 Å²	145	115.7 Å²	115.7	67%	0.671	61%	0.609	S	S	*	*	H	α-helix	trans	-75.9	-33	177.5	-103.3	-86.7	0	0	0	112.9	E63 L69	E63-H65 VanDerWaalsContact C-N 3.26Å; E63-H65 PolarHBondContact O-N 3.36Å; H65-L69 WeakPolarHBondContact O-CB 3.27Å; H65-L69 VanDerWaalsContact O-CD1 3.25Å; H65-L69 WeakPolarHBondContact O-CD1 3.38Å; H65-L69 PolarHBondContact O-N 2.87Å
66	E	40	Very low	55.2	Low	143 Å²	143	117.6 Å²	117.6	67%	0.668	61%	0.607	S	S	*	*	H	α-helix	trans	-76.8	-43.8	-173.6	-157.1	166.9	-174.9	0	0	111.7	E63 V68 L69 D70	E63-E66 PolarHBondContact O-N 3.31Å; E66-V68 PolarHBondContact O-N 2.94Å; E66-L69 WeakPolarHBondContact O-CB 3.11Å; E66-L69 PolarHBondContact O-N 3.47Å; E66-D70 PolarHBondContact O-N 3.25Å
67	L	49.3	Very low	57.8	Low	119 Å²	119	109.2 Å²	109.2	62%	0.623	57%	0.568	S	S	*	*	H	α-helix	trans	-69.9	-31.7	177.3	-64.5	174.5	0	0	0	113.5	D70 S71	L67-D70 PolarHBondContact O-N 2.83Å; L67-S71 PolarHBondContact O-N 3Å; L67-S71 PolarHBondContact O-OG 3.2Å
68	V	52.2	Low	60.5	Low	84 Å²	84	103.4 Å²	103.4	51%	0.509	54%	0.537	S	S	.	.	H	α-helix	trans	-75.8	-35.7	174.7	174	0	0	0	0	110.7	T64 E66 D70 N72	T64-V68 WeakPolarHBondContact O-CB 3.3Å; T64-V68 WeakPolarHBondContact O-CG2 3.44Å; E66-V68 PolarHBondContact O-N 2.94Å; V68-D70 VanDerWaalsContact C-N 3.25Å; V68-D70 PolarHBondContact O-N 3.34Å; V68-N72 WeakPolarHBondContact CG1-ND2 3.31Å; V68-N72 PolarHBondContact O-N 3.02Å; V68-N72 PolarHBondContact O-ND2 3.37Å
69	L	57	Low	63.6	Low	111 Å²	111	97.5 Å²	97.5	58%	0.581	51%	0.512	S	S	*	.	H	α-helix	trans	-57.5	-43.4	169.6	-114.2	85.7	0	0	0	110.6	H65 E66 L73	H65-L69 WeakPolarHBondContact O-CB 3.27Å; H65-L69 VanDerWaalsContact O-CD1 3.25Å; H65-L69 WeakPolarHBondContact O-CD1 3.38Å; H65-L69 PolarHBondContact O-N 2.87Å; E66-L69 WeakPolarHBondContact O-CB 3.11Å; E66-L69 PolarHBondContact O-N 3.47Å; L69-L73 WeakPolarHBondContact O-CB 3.22Å; L69-L73 PolarHBondContact O-N 3.4Å
70	D	75.3	Confident	66.7	Low	52 Å²	52	90 Å²	90	28%	0.278	48%	0.483	S	S	.	.	H	α-helix	trans	-63.6	-43.1	-177.5	-81.3	-11.9	0	0	0	113.5	E66 L67 V68 L73 K74 Y111	E66-D70 PolarHBondContact O-N 3.25Å; L67-D70 PolarHBondContact O-N 2.83Å; V68-D70 VanDerWaalsContact C-N 3.25Å; V68-D70 PolarHBondContact O-N 3.34Å; D70-L73 PolarHBondContact O-N 3.19Å; D70-K74 WeakPolarHBondContact O-CG 3.17Å; D70-K74 PolarHBondContact O-N 3.23Å; D70-Y111 WeakPolarHBondContact CB-OH 3.19Å; D70-Y111 VanDerWaalsContact CG-OH 3.25Å; D70-Y111 PolarHBondContact OD2-OH 3.48Å
71	S	81.8	Confident	69.4	Low	79 Å²	79	82.1 Å²	82.1	55%	0.552	45%	0.447	S	S	*	.	H	α-helix	trans	-68.8	-42.8	-178.8	-58.5	0	0	0	0	111.6	L67 K74 A75	L67-S71 PolarHBondContact O-N 3Å; L67-S71 PolarHBondContact O-OG 3.2Å; S71-K74 PolarHBondContact O-N 2.86Å; S71-A75 PolarHBondContact O-N 3.48Å
72	N	85.5	Confident	72.5	Confident	105 Å²	105	78.9 Å²	78.9	56%	0.561	41%	0.413	S	S	*	.	H	α-helix	trans	-67.3	-36.6	176.3	-71	-49.7	0	0	0	112.1	V68 A75 R76	V68-N72 WeakPolarHBondContact CG1-ND2 3.31Å; V68-N72 PolarHBondContact O-N 3.02Å; V68-N72 PolarHBondContact O-ND2 3.37Å; N72-A75 PolarHBondContact O-N 2.95Å; N72-R76 WeakPolarHBondContact O-CB 3.33Å; N72-R76 PolarHBondContact O-N 3.23Å
73	L	87.5	Confident	75.1	Confident	48 Å²	48	77 Å²	77	25%	0.251	41%	0.41	S	S	.	.	H	α-helix	trans	-64.5	-45.5	175.4	-175.9	145.7	0	0	0	111	L69 D70 R76 V77 L108	L69-L73 WeakPolarHBondContact O-CB 3.22Å; L69-L73 PolarHBondContact O-N 3.4Å; D70-L73 PolarHBondContact O-N 3.19Å; L73-R76 PolarHBondContact O-N 3.25Å; L73-V77 HydrophobicContact CD2-CG2 4.3Å; L73-V77 VanDerWaalsContact O-CG2 3.31Å; L73-V77 WeakPolarHBondContact O-CG2 3.44Å; L73-V77 PolarHBondContact O-N 3.29Å; L73-L108 HydrophobicContact CD2-CD1 4.05Å; L73-L108 HydrophobicContact CD2-CD2 4.19Å
74	K	89.7	Confident	77.6	Confident	65 Å²	65	72 Å²	72	28%	0.283	38%	0.384	S	S	.	.	H	α-helix	trans	-57.2	-50	174.5	-73.6	178.3	-173.4	179.9	0	111.6	D70 S71 R76 V77 L78 Y111 V112	D70-K74 WeakPolarHBondContact O-CG 3.17Å; D70-K74 PolarHBondContact O-N 3.23Å; S71-K74 PolarHBondContact O-N 2.86Å; K74-R76 VanDerWaalsContact C-N 3.34Å; K74-R76 PolarHBondContact O-N 2.98Å; K74-V77 PolarHBondContact O-N 3.48Å; K74-L78 WeakPolarHBondContact O-CB 3.48Å; K74-L78 VanDerWaalsContact O-CG 3.31Å; K74-L78 WeakPolarHBondContact O-CG 3.48Å; K74-L78 PolarHBondContact O-N 3.41Å; K74-Y111 HydrophobicContact CD-CE1 4.29Å; K74-Y111 WeakPolarHBondContact CE-OH 3.41Å; K74-Y111 HydrophobicContact CG-CD1 4.47Å; K74-Y111 HydrophobicContact CG-CE1 4.18Å; K74-Y111 PolarHBondContact NZ-OH 3.09Å; K74-V112 HydrophobicContact CG-CG2 4.27Å
75	A	91.3	Very high	80	Confident	36 Å²	36	67 Å²	67	30%	0.298	35%	0.354	S	S	.	.	H	α-helix	trans	-59.5	-43.8	179.3	0	0	0	0	0	112.1	S71 N72 V77 L78 E79 H123	S71-A75 PolarHBondContact O-N 3.48Å; N72-A75 PolarHBondContact O-N 2.95Å; A75-V77 PolarHBondContact O-N 3.31Å; A75-L78 PolarHBondContact O-N 3.22Å; A75-E79 WeakPolarHBondContact O-CB 3.34Å; A75-E79 PolarHBondContact O-N 3.44Å; A75-H123 WeakPolarHBondContact CA-NE2 3.25Å; A75-H123 PolarHBondContact O-CE1 3.43Å; A75-H123 PolarHBondContact O-NE2 2.91Å
76	R	90.8	Very high	82.5	Confident	167 Å²	167	63.7 Å²	63.7	63%	0.63	35%	0.345	S	S	*	.	H	α-helix	trans	-62.1	-43.7	178	-173.5	175.7	65.2	-173.9	-0.1	112.6	N72 L73 K74 E79 S80	N72-R76 WeakPolarHBondContact O-CB 3.33Å; N72-R76 PolarHBondContact O-N 3.23Å; L73-R76 PolarHBondContact O-N 3.25Å; K74-R76 VanDerWaalsContact C-N 3.34Å; K74-R76 PolarHBondContact O-N 2.98Å; R76-E79 PolarHBondContact O-N 3.43Å; R76-S80 PolarHBondContact O-N 3.48Å; R76-S80 PolarHBondContact O-OG 3.03Å
77	V	92	Very high	85.1	Confident	3 Å²	3	64.7 Å²	64.7	2%	0.018	35%	0.347	C	S	.	.	H	α-helix	trans	-69	-38.2	179	176.8	0	0	0	0	111.3	L73 K74 A75 S80 T81 L104 L108 V112	L73-V77 HydrophobicContact CD2-CG2 4.3Å; L73-V77 VanDerWaalsContact O-CG2 3.31Å; L73-V77 WeakPolarHBondContact O-CG2 3.44Å; L73-V77 PolarHBondContact O-N 3.29Å; K74-V77 PolarHBondContact O-N 3.48Å; A75-V77 PolarHBondContact O-N 3.31Å; V77-S80 WeakPolarHBondContact CA-OG 3.4Å; V77-S80 PolarHBondContact O-N 3.4Å; V77-S80 PolarHBondContact O-OG 2.9Å; V77-T81 WeakPolarHBondContact O-CB 3.47Å; V77-T81 PolarHBondContact O-N 2.9Å; V77-T81 PolarHBondContact O-OG1 3.46Å; V77-L104 HydrophobicContact CG1-CD1 4.3Å; V77-L104 HydrophobicContact CG2-CD1 3.66Å; V77-L108 HydrophobicContact CG2-CD2 4.2Å; V77-V112 HydrophobicContact CB-CG1 4.2Å; V77-V112 HydrophobicContact CB-CG2 4.26Å; V77-V112 HydrophobicContact CG1-CG1 4.05Å; V77-V112 HydrophobicContact CG1-CG2 4.17Å
78	L	92.6	Very high	87.2	Confident	13 Å²	13	62.9 Å²	62.9	7%	0.068	33%	0.333	C	S	.	.	H	α-helix	trans	-67.7	-38.8	175.9	-70.2	171	0	0	0	111.5	K74 A75 T81 L82 V112 I120 H123	K74-L78 WeakPolarHBondContact O-CB 3.48Å; K74-L78 VanDerWaalsContact O-CG 3.31Å; K74-L78 WeakPolarHBondContact O-CG 3.48Å; K74-L78 PolarHBondContact O-N 3.41Å; A75-L78 PolarHBondContact O-N 3.22Å; L78-T81 WeakPolarHBondContact O-CB 3.38Å; L78-T81 PolarHBondContact O-N 3.01Å; L78-L82 PolarHBondContact O-N 3.26Å; L78-V112 HydrophobicContact CD1-CG1 4.18Å; L78-V112 HydrophobicContact CD2-CG1 3.61Å; L78-V112 HydrophobicContact CG-CG1 3.54Å; L78-I120 HydrophobicContact CD2-CG1 4.1Å; L78-H123 HydrophobicContact CB-CB 4.06Å; L78-H123 HydrophobicContact CD1-CB 3.81Å; L78-H123 HydrophobicContact CG-CB 4.46Å
79	E	93.8	Very high	89.1	Confident	72 Å²	72	59.1 Å²	59.1	34%	0.336	31%	0.311	S	S	.	.	H	α-helix	trans	-65.2	-43.7	175	-165	62.8	-159.5	0	0	111.7	A75 R76 T81 L82 H123 R128	A75-E79 WeakPolarHBondContact O-CB 3.34Å; A75-E79 PolarHBondContact O-N 3.44Å; R76-E79 PolarHBondContact O-N 3.43Å; E79-T81 VanDerWaalsContact C-N 3.27Å; E79-T81 PolarHBondContact O-N 3.42Å; E79-L82 WeakPolarHBondContact O-CB 3.45Å; E79-L82 PolarHBondContact O-N 3.49Å; E79-L82 WeakPolarHBondContact OE2-CD1 3.47Å; E79-H123 IonicContact OE2-CE1 3.74Å; E79-H123 PolarHBondContact OE2-CE1 3.04Å; E79-H123 VanDerWaalsContact OE2-CE1 3.29Å; E79-H123 IonicContact OE2-ND1 3.35Å; E79-R128 IonicContact OE1-CZ 3.77Å; E79-R128 IonicContact OE1-NH2 3.78Å; E79-R128 PolarHBondContact OE1-NH2 3.4Å; E79-R128 IonicContact OE2-NH2 3.29Å
80	S	93	Very high	90.8	Very high	32 Å²	32	54 Å²	54	22%	0.224	28%	0.284	C	S	.	.	H	α-helix	trans	-65.2	-32.2	175	61.8	0	0	0	0	112.3	R76 V77 L82 A83 Y84 C98	R76-S80 PolarHBondContact O-N 3.48Å; R76-S80 PolarHBondContact O-OG 3.03Å; V77-S80 WeakPolarHBondContact CA-OG 3.4Å; V77-S80 PolarHBondContact O-N 3.4Å; V77-S80 PolarHBondContact O-OG 2.9Å; S80-L82 PolarHBondContact O-N 3.14Å; S80-A83 PolarHBondContact O-N 2.71Å; S80-Y84 WeakPolarHBondContact O-CD2 3.22Å; S80-C98 PolarHBondContact OG-SG 3.35Å
81	T	93.6	Very high	91.6	Very high	0 Å²	0	52.6 Å²	52.6	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-61.6	-29.6	176.4	-60.4	0	0	0	0	112	V77 L78 E79 A83 Y84 V85 A94 V95 I120	V77-T81 WeakPolarHBondContact O-CB 3.47Å; V77-T81 PolarHBondContact O-N 2.9Å; V77-T81 PolarHBondContact O-OG1 3.46Å; L78-T81 WeakPolarHBondContact O-CB 3.38Å; L78-T81 PolarHBondContact O-N 3.01Å; E79-T81 VanDerWaalsContact C-N 3.27Å; E79-T81 PolarHBondContact O-N 3.42Å; T81-A83 PolarHBondContact O-N 3.25Å; T81-A83 VanDerWaalsContact O-N 3.11Å; T81-Y84 PolarHBondContact O-N 3.45Å; T81-V85 PolarHBondContact O-N 3.14Å; T81-A94 HydrophobicContact CG2-CB 4Å; T81-V95 HydrophobicContact CG2-CB 4.47Å; T81-V95 HydrophobicContact CG2-CG2 3.98Å; T81-I120 HydrophobicContact CG2-CD1 3.98Å; T81-I120 HydrophobicContact CG2-CG2 4.31Å
82	L	93.5	Very high	92.1	Very high	4 Å²	4	55.8 Å²	55.8	2%	0.021	28%	0.278	C	S	.	.	T	Hydrogen-bonded Turn	trans	-59	-25.5	-179.9	-62.5	-177.9	0	0	0	113.5	L78 E79 S80 Y84 V85 W90 I120 F124 Y187	L78-L82 PolarHBondContact O-N 3.26Å; E79-L82 WeakPolarHBondContact O-CB 3.45Å; E79-L82 PolarHBondContact O-N 3.49Å; E79-L82 WeakPolarHBondContact OE2-CD1 3.47Å; S80-L82 PolarHBondContact O-N 3.14Å; L82-Y84 PolarHBondContact O-N 3.48Å; L82-V85 HydrophobicContact CD2-CG2 4.39Å; L82-W90 HydrophobicContact CD2-CH2 4.1Å; L82-W90 HydrophobicContact CD2-CZ3 4Å; L82-I120 HydrophobicContact CD2-CG2 3.92Å; L82-F124 HydrophobicContact CD1-CD2 4.06Å; L82-F124 HydrophobicContact CD2-CB 4.2Å; L82-F124 HydrophobicContact CD2-CD2 4.07Å; L82-Y187 VanDerWaalsContact O-CE1 3.31Å; L82-Y187 WeakPolarHBondContact O-CE1 3.49Å; L82-Y187 PolarHBondContact O-OH 3.02Å
83	A	93.5	Very high	92.4	Very high	80 Å²	80	56.5 Å²	56.5	66%	0.661	28%	0.278	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.4	-25.9	175	0	0	0	0	0	113	S80 T81	S80-A83 PolarHBondContact O-N 2.71Å; T81-A83 PolarHBondContact O-N 3.25Å; T81-A83 VanDerWaalsContact O-N 3.11Å
84	Y	93.5	Very high	92.7	Very high	49 Å²	49	54.2 Å²	54.2	19%	0.192	27%	0.266	C	S	.	.	T	Hydrogen-bonded Turn	trans	-95.5	-15.5	-176.2	-59.5	-84.4	0	0	0	113.1	S80 T81 L82 P86 K87 Y88 C98 T101	S80-Y84 WeakPolarHBondContact O-CD2 3.22Å; T81-Y84 PolarHBondContact O-N 3.45Å; L82-Y84 PolarHBondContact O-N 3.48Å; Y84-P86 VanDerWaalsContact C-CD 3.49Å; Y84-K87 PolarHBondContact O-N 2.78Å; Y84-Y88 HydrophobicContact CD1-CE2 4.28Å; Y84-Y88 WeakPolarHBondContact O-CD2 3.42Å; Y84-Y88 PolarHBondContact O-N 3.31Å; Y84-C98 HydrophobicContact CD2-CB 3.69Å; Y84-C98 HydrophobicContact CE2-CB 3.8Å; Y84-C98 HydrophobicContact CG-CB 4.5Å; Y84-T101 VanDerWaalsContact OH-CB 3.26Å; Y84-T101 WeakPolarHBondContact OH-CB 3.48Å; Y84-T101 WeakPolarHBondContact OH-CG2 3.43Å
85	V	93.8	Very high	92.8	Very high	0 Å²	0	51.1 Å²	51.1	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-56	-40.2	-179.9	170.6	0	0	0	0	113.6	T81 L82 K87 G89 W90 I120 Y187 V190	T81-V85 PolarHBondContact O-N 3.14Å; L82-V85 HydrophobicContact CD2-CG2 4.39Å; V85-K87 PolarHBondContact O-N 2.83Å; V85-K87 VanDerWaalsContact O-N 3.16Å; V85-G89 WeakPolarHBondContact O-CA 3.46Å; V85-G89 PolarHBondContact O-N 2.99Å; V85-W90 HydrophobicContact CG1-CD2 3.7Å; V85-W90 VanDerWaalsContact CG1-CE2 3.48Å; V85-W90 HydrophobicContact CG1-CE3 4.08Å; V85-W90 HydrophobicContact CG1-CG 4.23Å; V85-W90 HydrophobicContact CG1-CH2 4.11Å; V85-W90 HydrophobicContact CG1-CZ2 3.7Å; V85-W90 HydrophobicContact CG1-CZ3 4.28Å; V85-W90 HydrophobicContact CG2-CE3 4.18Å; V85-W90 HydrophobicContact CG2-CZ3 4.2Å; V85-I120 HydrophobicContact CG2-CG2 4.26Å; V85-Y187 HydrophobicContact CB-CD1 4.24Å; V85-Y187 HydrophobicContact CB-CE1 4.18Å; V85-Y187 HydrophobicContact CG1-CD1 3.88Å; V85-Y187 HydrophobicContact CG1-CE1 4.3Å; V85-V190 HydrophobicContact CG1-CG2 3.9Å
86	P	92.9	Very high	92.9	Very high	76 Å²	76	51.6 Å²	51.6	49%	0.494	25%	0.249	S	C	.	.	H	α-helix	trans	-62.1	-23.8	177	-25.2	36	0	0	0	114.1	Y84 Y187	Y84-P86 VanDerWaalsContact C-CD 3.49Å; P86-Y187 HydrophobicContact CG-CD1 4.18Å; P86-Y187 HydrophobicContact CG-CE1 4.11Å
87	K	93.7	Very high	93	Very high	163 Å²	163	44 Å²	44	71%	0.709	22%	0.222	S	C	*	.	H	α-helix	trans	-94.4	-45.9	-178.3	-174.1	-179.5	178	-169.4	0	113.1	Y84 V85	Y84-K87 PolarHBondContact O-N 2.78Å; V85-K87 PolarHBondContact O-N 2.83Å; V85-K87 VanDerWaalsContact O-N 3.16Å
88	Y	93.2	Very high	92.9	Very high	81 Å²	81	43.8 Å²	43.8	32%	0.318	22%	0.221	S	C	.	.	H	α-helix	trans	-101.5	-5.7	-175.1	-60.1	-79.6	0	0	0	113.7	Y84 S91 E93 A97	Y84-Y88 HydrophobicContact CD1-CE2 4.28Å; Y84-Y88 WeakPolarHBondContact O-CD2 3.42Å; Y84-Y88 PolarHBondContact O-N 3.31Å; Y88-S91 PolarHBondContact O-OG 2.84Å; Y88-E93 HydrophobicContact CD1-CB 4.45Å; Y88-A97 HydrophobicContact CD2-CB 4.02Å; Y88-A97 HydrophobicContact CE1-CB 4.39Å; Y88-A97 HydrophobicContact CE2-CB 3.44Å; Y88-A97 VanDerWaalsContact CE2-CB 3.44Å
89	G	92.9	Very high	92.8	Very high	6 Å²	6	43.3 Å²	43.3	6%	0.062	22%	0.218	C	C	.	.			trans	72.5	-170.5	-172.8	0	0	0	0	0	113.1	V85 S91	V85-G89 WeakPolarHBondContact O-CA 3.46Å; V85-G89 PolarHBondContact O-N 2.99Å; G89-S91 PolarHBondContact O-N 3.45Å
90	W	92.1	Very high	92.7	Very high	4 Å²	4	46.8 Å²	46.8	2%	0.015	24%	0.235	C	C	.	.	S	Bend	trans	-82.2	70.1	175.4	-59.8	94.8	0	0	0	109.8	L82 V85 G117 I120 V121 F124 Y187 V190 W191 A194 L197	L82-W90 HydrophobicContact CD2-CH2 4.1Å; L82-W90 HydrophobicContact CD2-CZ3 4Å; V85-W90 HydrophobicContact CG1-CD2 3.7Å; V85-W90 VanDerWaalsContact CG1-CE2 3.48Å; V85-W90 HydrophobicContact CG1-CE3 4.08Å; V85-W90 HydrophobicContact CG1-CG 4.23Å; V85-W90 HydrophobicContact CG1-CH2 4.11Å; V85-W90 HydrophobicContact CG1-CZ2 3.7Å; V85-W90 HydrophobicContact CG1-CZ3 4.28Å; V85-W90 HydrophobicContact CG2-CE3 4.18Å; V85-W90 HydrophobicContact CG2-CZ3 4.2Å; W90-G117 WeakPolarHBondContact O-CA 3.26Å; W90-I120 HydrophobicContact CE3-CB 4Å; W90-I120 HydrophobicContact CE3-CG2 3.86Å; W90-I120 HydrophobicContact CZ3-CB 4.17Å; W90-I120 HydrophobicContact CZ3-CG2 3.67Å; W90-V121 HydrophobicContact CB-CG2 4.09Å; W90-V121 HydrophobicContact CD2-CG2 3.56Å; W90-V121 HydrophobicContact CE3-CB 4.3Å; W90-V121 HydrophobicContact CE3-CG2 3.35Å; W90-V121 HydrophobicContact CG-CG2 3.89Å; W90-V121 HydrophobicContact CZ3-CB 4.49Å; W90-V121 HydrophobicContact CZ3-CG2 3.96Å; W90-F124 HydrophobicContact CH2-CB 3.95Å; W90-F124 HydrophobicContact CH2-CD1 4.4Å; W90-F124 HydrophobicContact CH2-CD2 4.11Å; W90-F124 AromaticContact CH2-CG 3.9Å; W90-F124 HydrophobicContact CH2-CG 3.9Å; W90-F124 HydrophobicContact CZ3-CB 4.15Å; W90-Y187 HydrophobicContact CZ2-CD1 4.4Å; W90-Y187 HydrophobicContact CZ2-CG 4.27Å; W90-V190 VanDerWaalsContact CD1-O 3.22Å; W90-V190 PolarHBondContact NE1-O 3.41Å; W90-W191 HydrophobicContact CH2-CZ3 4.18Å; W90-W191 AromaticContact CZ2-CE3 3.86Å; W90-W191 HydrophobicContact CZ2-CE3 3.86Å; W90-W191 AromaticContact CZ2-CZ3 3.6Å; W90-W191 HydrophobicContact CZ2-CZ3 3.6Å; W90-A194 HydrophobicContact CD2-CB 4.17Å; W90-A194 HydrophobicContact CG-CB 4.01Å; W90-L197 HydrophobicContact CB-CD1 4.05Å
91	S	92.7	Very high	92.7	Very high	22 Å²	22	49.7 Å²	49.7	15%	0.154	25%	0.251	C	S	.	.	S	Bend	trans	-130.5	164.9	-171.8	69.6	0	0	0	0	111.8	Y88 G89 E93 A94	Y88-S91 PolarHBondContact O-OG 2.84Å; G89-S91 PolarHBondContact O-N 3.45Å; S91-E93 PolarHBondContact O-N 3.34Å; S91-A94 WeakPolarHBondContact O-CB 3.2Å; S91-A94 PolarHBondContact O-N 3.31Å; S91-A94 PolarHBondContact OG-N 2.92Å
92	R	92.2	Very high	92.4	Very high	145 Å²	145	55.1 Å²	55.1	55%	0.547	28%	0.276	S	S	.	.	H	α-helix	trans	-63	-32	172.6	-165.9	-178.5	73.8	-174.3	-1	111.6	A94 V95 E96	R92-A94 PolarHBondContact O-N 3.32Å; R92-V95 PolarHBondContact O-N 2.99Å; R92-V95 VanDerWaalsContact O-N 3.09Å; R92-E96 IonicContact CZ-OE1 3.38Å; R92-E96 IonicContact NE-OE1 2.73Å; R92-E96 PolarHBondContact NE-OE1 3.36Å; R92-E96 IonicContact NH2-OE1 2.78Å; R92-E96 PolarHBondContact NH2-OE1 2.82Å; R92-E96 PolarHBondContact O-N 3.03Å
93	E	92.8	Very high	92.2	Very high	120 Å²	120	58.1 Å²	58.1	56%	0.561	31%	0.309	S	S	*	.	H	α-helix	trans	-60	-34.2	178	-59.3	175	-176.5	0	0	112	Y88 S91 V95 E96 A97	Y88-E93 HydrophobicContact CD1-CB 4.45Å; S91-E93 PolarHBondContact O-N 3.34Å; E93-V95 VanDerWaalsContact C-N 3.34Å; E93-V95 PolarHBondContact O-N 3.35Å; E93-E96 PolarHBondContact O-N 3.43Å; E93-A97 VanDerWaalsContact O-CB 3.31Å; E93-A97 WeakPolarHBondContact O-CB 3.45Å; E93-A97 PolarHBondContact O-N 3.1Å
94	A	93.1	Very high	91.9	Very high	0 Å²	0	56.4 Å²	56.4	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-61.5	-42.2	175	0	0	0	0	0	112.1	T81 S91 R92 C98	T81-A94 HydrophobicContact CG2-CB 4Å; S91-A94 WeakPolarHBondContact O-CB 3.2Å; S91-A94 PolarHBondContact O-N 3.31Å; S91-A94 PolarHBondContact OG-N 2.92Å; R92-A94 PolarHBondContact O-N 3.32Å; A94-C98 WeakPolarHBondContact O-CB 3.32Å; A94-C98 PolarHBondContact O-N 3.26Å
95	V	92.4	Very high	91.5	Very high	0 Å²	0	58.1 Å²	58.1	0%	0	31%	0.305	C	S	.	.	H	α-helix	trans	-69.5	-43.4	177.7	-171.2	0	0	0	0	110.1	T81 R92 E93 A97 C98 C99 H109 A113 I120	T81-V95 HydrophobicContact CG2-CB 4.47Å; T81-V95 HydrophobicContact CG2-CG2 3.98Å; R92-V95 PolarHBondContact O-N 2.99Å; R92-V95 VanDerWaalsContact O-N 3.09Å; E93-V95 VanDerWaalsContact C-N 3.34Å; E93-V95 PolarHBondContact O-N 3.35Å; V95-A97 PolarHBondContact O-N 3.43Å; V95-C98 WeakPolarHBondContact O-CB 3.31Å; V95-C98 PolarHBondContact O-N 2.84Å; V95-C99 PolarHBondContact O-N 3.11Å; V95-C99 PolarHBondContact O-SG 3.14Å; V95-H109 HydrophobicContact CB-CB 4.09Å; V95-H109 HydrophobicContact CG1-CB 3.59Å; V95-A113 HydrophobicContact CG2-CB 4.05Å; V95-I120 HydrophobicContact CG2-CD1 3.51Å; V95-I120 HydrophobicContact CG2-CG1 3.95Å
96	E	92	Very high	90.7	Very high	46 Å²	46	63.2 Å²	63.2	22%	0.215	34%	0.338	C	S	.	.	H	α-helix	trans	-60.4	-45.1	177.5	-70.7	172.2	-159.1	0	0	111.5	R92 E93 C98 C99 Q100 H109	R92-E96 IonicContact CZ-OE1 3.38Å; R92-E96 IonicContact NE-OE1 2.73Å; R92-E96 PolarHBondContact NE-OE1 3.36Å; R92-E96 IonicContact NH2-OE1 2.78Å; R92-E96 PolarHBondContact NH2-OE1 2.82Å; R92-E96 PolarHBondContact O-N 3.03Å; E93-E96 PolarHBondContact O-N 3.43Å; E96-C98 VanDerWaalsContact C-N 3.34Å; E96-C98 PolarHBondContact O-N 3.07Å; E96-C99 PolarHBondContact O-N 2.82Å; E96-Q100 VanDerWaalsContact O-CG 3.27Å; E96-Q100 WeakPolarHBondContact O-CG 3.42Å; E96-Q100 PolarHBondContact O-N 2.98Å; E96-H109 HydrophobicContact CG-CB 4.07Å; E96-H109 IonicContact OE1-CD2 2.67Å; E96-H109 IonicContact OE1-NE2 2.67Å
97	A	92.8	Very high	90.3	Very high	7 Å²	7	62 Å²	62	6%	0.058	34%	0.339	C	S	.	.	H	α-helix	trans	-64	-38.3	175.9	0	0	0	0	0	112.4	Y88 E93 V95 T101	Y88-A97 HydrophobicContact CD2-CB 4.02Å; Y88-A97 HydrophobicContact CE1-CB 4.39Å; Y88-A97 HydrophobicContact CE2-CB 3.44Å; Y88-A97 VanDerWaalsContact CE2-CB 3.44Å; E93-A97 VanDerWaalsContact O-CB 3.31Å; E93-A97 WeakPolarHBondContact O-CB 3.45Å; E93-A97 PolarHBondContact O-N 3.1Å; V95-A97 PolarHBondContact O-N 3.43Å; A97-T101 PolarHBondContact O-N 3.4Å; A97-T101 PolarHBondContact O-OG1 2.93Å
98	C	91.7	Very high	89.9	Confident	0 Å²	0	55.4 Å²	55.4	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-63.3	-47.6	173.7	-175.2	0	0	0	0	111.3	S80 Y84 A94 V95 E96 Q100 T101 E102	S80-C98 PolarHBondContact OG-SG 3.35Å; Y84-C98 HydrophobicContact CD2-CB 3.69Å; Y84-C98 HydrophobicContact CE2-CB 3.8Å; Y84-C98 HydrophobicContact CG-CB 4.5Å; A94-C98 WeakPolarHBondContact O-CB 3.32Å; A94-C98 PolarHBondContact O-N 3.26Å; V95-C98 WeakPolarHBondContact O-CB 3.31Å; V95-C98 PolarHBondContact O-N 2.84Å; E96-C98 VanDerWaalsContact C-N 3.34Å; E96-C98 PolarHBondContact O-N 3.07Å; C98-Q100 VanDerWaalsContact C-N 3.32Å; C98-Q100 PolarHBondContact O-N 2.69Å; C98-T101 PolarHBondContact O-N 2.94Å; C98-E102 WeakPolarHBondContact O-CB 3.48Å; C98-E102 WeakPolarHBondContact O-CG 3.39Å; C98-E102 PolarHBondContact O-N 3.3Å
99	C	90.3	Very high	89.6	Confident	2 Å²	2	53.1 Å²	53.1	1%	0.014	30%	0.304	C	S	.	.	H	α-helix	trans	-61.8	-40.6	178.7	-68.2	0	0	0	0	112	V95 E96 G103 L104	V95-C99 PolarHBondContact O-N 3.11Å; V95-C99 PolarHBondContact O-SG 3.14Å; E96-C99 PolarHBondContact O-N 2.82Å; C99-G103 PolarHBondContact O-N 2.93Å; C99-L104 HydrophobicContact CB-CB 4.15Å; C99-L104 PolarHBondContact O-N 3.1Å
100	Q	91.5	Very high	89.3	Confident	146 Å²	146	55.7 Å²	55.7	68%	0.682	32%	0.324	S	S	*	.	H	α-helix	trans	-63.8	-39.8	176.7	-72.6	172.8	14.5	0	0	112.3	E96 C98	E96-Q100 VanDerWaalsContact O-CG 3.27Å; E96-Q100 WeakPolarHBondContact O-CG 3.42Å; E96-Q100 PolarHBondContact O-N 2.98Å; C98-Q100 VanDerWaalsContact C-N 3.32Å; C98-Q100 PolarHBondContact O-N 2.69Å
101	T	91.9	Very high	88.9	Confident	93 Å²	93	60 Å²	60	57%	0.571	34%	0.341	S	S	*	.	H	α-helix	trans	-76.3	-37.8	-177.5	-49.9	0	0	0	0	112.3	Y84 A97 C98 G103	Y84-T101 VanDerWaalsContact OH-CB 3.26Å; Y84-T101 WeakPolarHBondContact OH-CB 3.48Å; Y84-T101 WeakPolarHBondContact OH-CG2 3.43Å; A97-T101 PolarHBondContact O-N 3.4Å; A97-T101 PolarHBondContact O-OG1 2.93Å; C98-T101 PolarHBondContact O-N 2.94Å; T101-G103 PolarHBondContact O-N 3.39Å
102	E	88.9	Confident	88.7	Confident	113 Å²	113	59.2 Å²	59.2	53%	0.528	34%	0.336	S	S	.	.	T	Hydrogen-bonded Turn	trans	-78.7	-3	177.8	-67.3	-67.7	148.5	0	0	113.4	C98 L104	C98-E102 WeakPolarHBondContact O-CB 3.48Å; C98-E102 WeakPolarHBondContact O-CG 3.39Å; C98-E102 PolarHBondContact O-N 3.3Å; E102-L104 VanDerWaalsContact C-N 3.28Å; E102-L104 HydrophobicContact CB-CD1 3.89Å; E102-L104 HydrophobicContact CB-CG 3.91Å; E102-L104 PolarHBondContact O-N 2.9Å
103	G	87.7	Confident	88.4	Confident	68 Å²	68	52.5 Å²	52.5	70%	0.701	31%	0.311	S	S	*	.	T	Hydrogen-bonded Turn	trans	68.3	25.3	-176.7	0	0	0	0	0	113.7	C99 T101	C99-G103 PolarHBondContact O-N 2.93Å; T101-G103 PolarHBondContact O-N 3.39Å
104	L	86.8	Confident	88	Confident	44 Å²	44	51.5 Å²	51.5	23%	0.23	32%	0.315	C	S	.	.			trans	-81.5	154.3	178	-65.3	168.5	0	0	0	111.1	V77 C99 E102 L108	V77-L104 HydrophobicContact CG1-CD1 4.3Å; V77-L104 HydrophobicContact CG2-CD1 3.66Å; C99-L104 HydrophobicContact CB-CB 4.15Å; C99-L104 PolarHBondContact O-N 3.1Å; E102-L104 VanDerWaalsContact C-N 3.28Å; E102-L104 HydrophobicContact CB-CD1 3.89Å; E102-L104 HydrophobicContact CB-CG 3.91Å; E102-L104 PolarHBondContact O-N 2.9Å; L104-L108 HydrophobicContact CB-CD2 3.89Å; L104-L108 HydrophobicContact CD1-CD2 3.97Å; L104-L108 HydrophobicContact CD2-CD2 4.17Å; L104-L108 HydrophobicContact CG-CD2 4.24Å
105	P	85.8	Confident	87.5	Confident	84 Å²	84	55.5 Å²	55.5	55%	0.545	33%	0.334	S	S	.	.			trans	-54.2	133.6	179.8	-26.4	34.5	0	0	0	112.1	G107 L108	P105-G107 PolarHBondContact O-N 3.28Å; P105-L108 WeakPolarHBondContact O-CB 3.41Å; P105-L108 PolarHBondContact O-N 3.5Å
106	P	77.7	Confident	87.3	Confident	108 Å²	108	56 Å²	56	70%	0.701	34%	0.338	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.4	-14.8	-172.7	24.7	-34.4	0	0	0	113.9	H109	P106-H109 PolarHBondContact O-CE1 3.34Å; P106-H109 PolarHBondContact O-ND1 3.42Å
107	G	84.5	Confident	87.2	Confident	49 Å²	49	54.2 Å²	54.2	51%	0.505	33%	0.332	S	S	.	.	T	Hydrogen-bonded Turn	trans	-87.8	-6.6	172.9	0	0	0	0	0	114.7	P105 H109 A110	P105-G107 PolarHBondContact O-N 3.28Å; G107-H109 VanDerWaalsContact C-N 3.27Å; G107-H109 PolarHBondContact O-N 2.97Å; G107-A110 PolarHBondContact O-N 2.96Å
108	L	85.7	Confident	87.2	Confident	26 Å²	26	54.1 Å²	54.1	14%	0.136	33%	0.331	C	S	.	.	H	α-helix	trans	-66	-30.3	-173.5	-173.2	65.4	0	0	0	112.4	L73 V77 L104 P105 A110 Y111 V112	L73-L108 HydrophobicContact CD2-CD1 4.05Å; L73-L108 HydrophobicContact CD2-CD2 4.19Å; V77-L108 HydrophobicContact CG2-CD2 4.2Å; L104-L108 HydrophobicContact CB-CD2 3.89Å; L104-L108 HydrophobicContact CD1-CD2 3.97Å; L104-L108 HydrophobicContact CD2-CD2 4.17Å; L104-L108 HydrophobicContact CG-CD2 4.24Å; P105-L108 WeakPolarHBondContact O-CB 3.41Å; P105-L108 PolarHBondContact O-N 3.5Å; L108-A110 PolarHBondContact O-N 3.42Å; L108-Y111 HydrophobicContact CD1-CD1 3.98Å; L108-Y111 WeakPolarHBondContact O-CB 3.4Å; L108-Y111 PolarHBondContact O-N 3.37Å; L108-V112 HydrophobicContact CD1-CG2 4.07Å; L108-V112 HydrophobicContact CD2-CG2 4.42Å; L108-V112 HydrophobicContact CG-CG2 3.78Å; L108-V112 WeakPolarHBondContact O-CG2 3.43Å; L108-V112 PolarHBondContact O-N 3.05Å
109	H	85.2	Confident	87.2	Confident	32 Å²	32	55.2 Å²	55.2	15%	0.148	34%	0.337	C	S	.	.	H	α-helix	trans	-56.4	-37	177.1	67.8	-87.2	0	0	0	112.4	V95 E96 P106 G107 Y111 V112 A113	V95-H109 HydrophobicContact CB-CB 4.09Å; V95-H109 HydrophobicContact CG1-CB 3.59Å; E96-H109 HydrophobicContact CG-CB 4.07Å; E96-H109 IonicContact OE1-CD2 2.67Å; E96-H109 IonicContact OE1-NE2 2.67Å; P106-H109 PolarHBondContact O-CE1 3.34Å; P106-H109 PolarHBondContact O-ND1 3.42Å; G107-H109 VanDerWaalsContact C-N 3.27Å; G107-H109 PolarHBondContact O-N 2.97Å; H109-Y111 VanDerWaalsContact C-N 3.3Å; H109-Y111 PolarHBondContact O-N 3.46Å; H109-V112 PolarHBondContact O-N 3.3Å; H109-A113 PolarHBondContact O-N 3.38Å
110	A	86.6	Confident	87.3	Confident	60 Å²	60	55.1 Å²	55.1	50%	0.496	34%	0.336	S	S	.	.	H	α-helix	trans	-70.5	-26.6	178	0	0	0	0	0	112.8	G107 L108	G107-A110 PolarHBondContact O-N 2.96Å; L108-A110 PolarHBondContact O-N 3.42Å
111	Y	85.6	Confident	87.5	Confident	95 Å²	95	48.2 Å²	48.2	37%	0.373	30%	0.304	S	S	.	.	H	α-helix	trans	-82.6	-38.7	175.4	179.2	-110.7	0	0	0	112.6	D70 K74 L108 H109	D70-Y111 WeakPolarHBondContact CB-OH 3.19Å; D70-Y111 VanDerWaalsContact CG-OH 3.25Å; D70-Y111 PolarHBondContact OD2-OH 3.48Å; K74-Y111 HydrophobicContact CD-CE1 4.29Å; K74-Y111 WeakPolarHBondContact CE-OH 3.41Å; K74-Y111 HydrophobicContact CG-CD1 4.47Å; K74-Y111 HydrophobicContact CG-CE1 4.18Å; K74-Y111 PolarHBondContact NZ-OH 3.09Å; L108-Y111 HydrophobicContact CD1-CD1 3.98Å; L108-Y111 WeakPolarHBondContact O-CB 3.4Å; L108-Y111 PolarHBondContact O-N 3.37Å; H109-Y111 VanDerWaalsContact C-N 3.3Å; H109-Y111 PolarHBondContact O-N 3.46Å
112	V	86.6	Confident	87.5	Confident	6 Å²	6	44.8 Å²	44.8	4%	0.036	28%	0.282	C	S	.	.	H	α-helix	trans	-78.1	-41.6	-176.6	173.7	0	0	0	0	111.7	K74 V77 L78 L108 H109	K74-V112 HydrophobicContact CG-CG2 4.27Å; V77-V112 HydrophobicContact CB-CG1 4.2Å; V77-V112 HydrophobicContact CB-CG2 4.26Å; V77-V112 HydrophobicContact CG1-CG1 4.05Å; V77-V112 HydrophobicContact CG1-CG2 4.17Å; L78-V112 HydrophobicContact CD1-CG1 4.18Å; L78-V112 HydrophobicContact CD2-CG1 3.61Å; L78-V112 HydrophobicContact CG-CG1 3.54Å; L108-V112 HydrophobicContact CD1-CG2 4.07Å; L108-V112 HydrophobicContact CD2-CG2 4.42Å; L108-V112 HydrophobicContact CG-CG2 3.78Å; L108-V112 WeakPolarHBondContact O-CG2 3.43Å; L108-V112 PolarHBondContact O-N 3.05Å; H109-V112 PolarHBondContact O-N 3.3Å
113	A	86.2	Confident	87.7	Confident	3 Å²	3	40.8 Å²	40.8	3%	0.025	26%	0.263	C	S	.	.			trans	-131.8	72	-176.3	0	0	0	0	0	111	V95 H109 Q115 G116 D119	V95-A113 HydrophobicContact CG2-CB 4.05Å; H109-A113 PolarHBondContact O-N 3.38Å; A113-Q115 PolarHBondContact O-N 3.02Å; A113-G116 PolarHBondContact O-N 2.94Å; A113-D119 VanDerWaalsContact CA-OD2 3.3Å; A113-D119 WeakPolarHBondContact CA-OD2 3.48Å; A113-D119 HydrophobicContact CB-CB 4.12Å
114	P	84.6	Confident	88	Confident	99 Å²	99	37.5 Å²	37.5	64%	0.643	23%	0.23	S	C	*	.	T	Hydrogen-bonded Turn	trans	-58.9	-29	-178.2	24.5	-36	0	0	0	113.7	D119	P114-D119 WeakPolarHBondContact CD-OD2 3.44Å; P114-D119 VanDerWaalsContact N-OD2 3.11Å
115	Q	84	Confident	88.3	Confident	85 Å²	85	36.4 Å²	36.4	40%	0.397	22%	0.222	S	C	.	.	T	Hydrogen-bonded Turn	trans	-98	5.5	179	-57.2	-174.7	85.8	0	0	112.6	A113 I118 D119	A113-Q115 PolarHBondContact O-N 3.02Å; Q115-I118 HydrophobicContact CB-CG2 3.26Å; Q115-I118 HydrophobicContact CG-CG2 4.31Å; Q115-D119 WeakPolarHBondContact CB-OD2 3.43Å; Q115-D119 PolarHBondContact N-OD2 3.19Å; Q115-D119 PolarHBondContact NE2-OD1 3.26Å
116	G	87	Confident	88.6	Confident	10 Å²	10	34.7 Å²	34.7	10%	0.103	22%	0.215	C	C	.	.	T	Hydrogen-bonded Turn	trans	74.5	-128.8	-177.9	0	0	0	0	0	112.2	A113 I118 D119	A113-G116 PolarHBondContact O-N 2.94Å; G116-I118 VanDerWaalsContact C-N 3.27Å; G116-I118 PolarHBondContact O-N 3.4Å; G116-D119 PolarHBondContact O-N 3.29Å
117	G	89.8	Confident	89.4	Confident	8 Å²	8	30.8 Å²	30.8	8%	0.082	19%	0.19	C	C	.	.	H	α-helix	trans	-61.7	-28.3	-169.5	0	0	0	0	0	115.6	W90 D119 I120 V121	W90-G117 WeakPolarHBondContact O-CA 3.26Å; G117-D119 VanDerWaalsContact C-N 3.34Å; G117-D119 PolarHBondContact O-N 3.01Å; G117-I120 WeakPolarHBondContact O-CB 3.42Å; G117-I120 PolarHBondContact O-N 3.33Å; G117-V121 WeakPolarHBondContact O-CG2 3.31Å; G117-V121 PolarHBondContact O-N 2.96Å; G117-V121 VanDerWaalsContact O-N 3.14Å
118	I	92.3	Very high	89.9	Confident	5 Å²	5	29.2 Å²	29.2	3%	0.026	17%	0.168	C	C	.	.	H	α-helix	trans	-64.7	-37.6	-178	-174.5	64.3	0	0	0	112	Q115 G116 I120 V121 L122 L197 L198 N203	Q115-I118 HydrophobicContact CB-CG2 3.26Å; Q115-I118 HydrophobicContact CG-CG2 4.31Å; G116-I118 VanDerWaalsContact C-N 3.27Å; G116-I118 PolarHBondContact O-N 3.4Å; I118-I120 PolarHBondContact O-N 2.96Å; I118-V121 PolarHBondContact O-N 3.27Å; I118-V121 VanDerWaalsContact O-N 3.11Å; I118-L122 HydrophobicContact CD1-CD1 4.49Å; I118-L122 HydrophobicContact CD1-CG 4.21Å; I118-L122 HydrophobicContact CG1-CD1 3.84Å; I118-L122 HydrophobicContact CG1-CG 4.06Å; I118-L122 WeakPolarHBondContact O-CB 3.49Å; I118-L122 VanDerWaalsContact O-CG 3.22Å; I118-L122 WeakPolarHBondContact O-CG 3.43Å; I118-L122 PolarHBondContact O-N 3Å; I118-L197 HydrophobicContact CD1-CB 4.26Å; I118-L198 HydrophobicContact CD1-CD2 3.8Å; I118-L198 HydrophobicContact CD1-CG 4.34Å; I118-N203 HydrophobicContact CD1-CB 4.21Å; I118-N203 HydrophobicContact CG1-CB 4.49Å
119	D	92.2	Very high	90.3	Very high	24 Å²	24	28.9 Å²	28.9	13%	0.128	17%	0.167	C	C	.	.	H	α-helix	trans	-65.8	-32.4	-178.9	-60.1	-37.4	0	0	0	110.7	A113 P114 Q115 G116 G117 H123	A113-D119 VanDerWaalsContact CA-OD2 3.3Å; A113-D119 WeakPolarHBondContact CA-OD2 3.48Å; A113-D119 HydrophobicContact CB-CB 4.12Å; P114-D119 WeakPolarHBondContact CD-OD2 3.44Å; P114-D119 VanDerWaalsContact N-OD2 3.11Å; Q115-D119 WeakPolarHBondContact CB-OD2 3.43Å; Q115-D119 PolarHBondContact N-OD2 3.19Å; Q115-D119 PolarHBondContact NE2-OD1 3.26Å; G116-D119 PolarHBondContact O-N 3.29Å; G117-D119 VanDerWaalsContact C-N 3.34Å; G117-D119 PolarHBondContact O-N 3.01Å; D119-H123 WeakPolarHBondContact O-CB 3.38Å; D119-H123 PolarHBondContact O-N 3.2Å
120	I	93.3	Very high	90.7	Very high	0 Å²	0	33 Å²	33	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-67.4	-44.8	173	-41.7	171.4	0	0	0	110.6	L78 T81 L82 V85 W90 V95 G117 I118 H123 F124	L78-I120 HydrophobicContact CD2-CG1 4.1Å; T81-I120 HydrophobicContact CG2-CD1 3.98Å; T81-I120 HydrophobicContact CG2-CG2 4.31Å; L82-I120 HydrophobicContact CD2-CG2 3.92Å; V85-I120 HydrophobicContact CG2-CG2 4.26Å; W90-I120 HydrophobicContact CE3-CB 4Å; W90-I120 HydrophobicContact CE3-CG2 3.86Å; W90-I120 HydrophobicContact CZ3-CB 4.17Å; W90-I120 HydrophobicContact CZ3-CG2 3.67Å; V95-I120 HydrophobicContact CG2-CD1 3.51Å; V95-I120 HydrophobicContact CG2-CG1 3.95Å; G117-I120 WeakPolarHBondContact O-CB 3.42Å; G117-I120 PolarHBondContact O-N 3.33Å; I118-I120 PolarHBondContact O-N 2.96Å; I120-H123 PolarHBondContact O-N 3.35Å; I120-F124 WeakPolarHBondContact O-CB 3.16Å; I120-F124 PolarHBondContact O-N 3.3Å
121	V	94.1	Very high	91.1	Very high	0 Å²	0	32.8 Å²	32.8	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-62.9	-44.9	177.9	176.9	0	0	0	0	110.5	W90 G117 I118 F124 Y125 A194 L198	W90-V121 HydrophobicContact CB-CG2 4.09Å; W90-V121 HydrophobicContact CD2-CG2 3.56Å; W90-V121 HydrophobicContact CE3-CB 4.3Å; W90-V121 HydrophobicContact CE3-CG2 3.35Å; W90-V121 HydrophobicContact CG-CG2 3.89Å; W90-V121 HydrophobicContact CZ3-CB 4.49Å; W90-V121 HydrophobicContact CZ3-CG2 3.96Å; G117-V121 WeakPolarHBondContact O-CG2 3.31Å; G117-V121 PolarHBondContact O-N 2.96Å; G117-V121 VanDerWaalsContact O-N 3.14Å; I118-V121 PolarHBondContact O-N 3.27Å; I118-V121 VanDerWaalsContact O-N 3.11Å; V121-F124 WeakPolarHBondContact O-CB 3.38Å; V121-F124 PolarHBondContact O-N 3.02Å; V121-Y125 HydrophobicContact CG1-CD2 3.8Å; V121-Y125 HydrophobicContact CG1-CE2 3.84Å; V121-Y125 WeakPolarHBondContact O-CD2 3.3Å; V121-Y125 PolarHBondContact O-N 3.43Å; V121-A194 HydrophobicContact CG1-CB 4.12Å; V121-A194 HydrophobicContact CG2-CB 3.71Å; V121-L198 HydrophobicContact CG1-CD1 3.75Å; V121-L198 HydrophobicContact CG1-CD2 3.98Å; V121-L198 HydrophobicContact CG1-CG 3.9Å
122	L	92.8	Very high	91.5	Very high	22 Å²	22	28.3 Å²	28.3	12%	0.115	16%	0.158	C	C	.	.	H	α-helix	trans	-63.3	-44.4	177.7	-66.8	168	0	0	0	111.2	I118 F124 Y125 A126 L198 L206 M210	I118-L122 HydrophobicContact CD1-CD1 4.49Å; I118-L122 HydrophobicContact CD1-CG 4.21Å; I118-L122 HydrophobicContact CG1-CD1 3.84Å; I118-L122 HydrophobicContact CG1-CG 4.06Å; I118-L122 WeakPolarHBondContact O-CB 3.49Å; I118-L122 VanDerWaalsContact O-CG 3.22Å; I118-L122 WeakPolarHBondContact O-CG 3.43Å; I118-L122 PolarHBondContact O-N 3Å; L122-F124 VanDerWaalsContact C-N 3.32Å; L122-F124 PolarHBondContact O-N 2.96Å; L122-Y125 PolarHBondContact O-N 2.85Å; L122-A126 WeakPolarHBondContact O-CB 3.35Å; L122-A126 PolarHBondContact O-N 3.08Å; L122-L198 HydrophobicContact CD2-CD2 4.33Å; L122-L206 HydrophobicContact CD1-CD2 3.39Å; L122-L206 HydrophobicContact CD2-CD2 3.54Å; L122-L206 HydrophobicContact CD2-CG 3.78Å; L122-L206 HydrophobicContact CG-CD2 4.08Å; L122-M210 HydrophobicContact CD2-SD 3.47Å; L122-M210 WeakPolarHBondContact CD2-SD 3.41Å; L122-M210 VanDerWaalsContact O-CE 3.27Å; L122-M210 WeakPolarHBondContact O-CE 3.32Å
123	H	93.1	Very high	91.8	Very high	28 Å²	28	28.8 Å²	28.8	13%	0.13	16%	0.162	C	C	.	.	H	α-helix	trans	-59.6	-44.2	173.5	-178.2	-95.2	0	0	0	111.5	A75 L78 E79 D119 I120 Y125 A126 T127	A75-H123 WeakPolarHBondContact CA-NE2 3.25Å; A75-H123 PolarHBondContact O-CE1 3.43Å; A75-H123 PolarHBondContact O-NE2 2.91Å; L78-H123 HydrophobicContact CB-CB 4.06Å; L78-H123 HydrophobicContact CD1-CB 3.81Å; L78-H123 HydrophobicContact CG-CB 4.46Å; E79-H123 IonicContact OE2-CE1 3.74Å; E79-H123 PolarHBondContact OE2-CE1 3.04Å; E79-H123 VanDerWaalsContact OE2-CE1 3.29Å; E79-H123 IonicContact OE2-ND1 3.35Å; D119-H123 WeakPolarHBondContact O-CB 3.38Å; D119-H123 PolarHBondContact O-N 3.2Å; I120-H123 PolarHBondContact O-N 3.35Å; H123-Y125 PolarHBondContact O-N 3.16Å; H123-A126 PolarHBondContact O-N 3.15Å; H123-T127 PolarHBondContact CE1-OG1 2.98Å; H123-T127 WeakPolarHBondContact O-CB 3.46Å; H123-T127 PolarHBondContact O-N 3.06Å; H123-T127 PolarHBondContact O-OG1 3.16Å
124	F	94.7	Very high	92.2	Very high	0 Å²	0	32.6 Å²	32.6	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-57.4	-51.9	175.1	176.4	-92.1	0	0	0	111.6	L82 W90 I120 V121 L122 A126 T127 R128 I184 Y187 W191	L82-F124 HydrophobicContact CD1-CD2 4.06Å; L82-F124 HydrophobicContact CD2-CB 4.2Å; L82-F124 HydrophobicContact CD2-CD2 4.07Å; W90-F124 HydrophobicContact CH2-CB 3.95Å; W90-F124 HydrophobicContact CH2-CD1 4.4Å; W90-F124 HydrophobicContact CH2-CD2 4.11Å; W90-F124 AromaticContact CH2-CG 3.9Å; W90-F124 HydrophobicContact CH2-CG 3.9Å; W90-F124 HydrophobicContact CZ3-CB 4.15Å; I120-F124 WeakPolarHBondContact O-CB 3.16Å; I120-F124 PolarHBondContact O-N 3.3Å; V121-F124 WeakPolarHBondContact O-CB 3.38Å; V121-F124 PolarHBondContact O-N 3.02Å; L122-F124 VanDerWaalsContact C-N 3.32Å; L122-F124 PolarHBondContact O-N 2.96Å; F124-A126 VanDerWaalsContact C-N 3.34Å; F124-A126 PolarHBondContact O-N 3.46Å; F124-T127 PolarHBondContact O-N 3.03Å; F124-R128 HydrophobicContact CD1-CG 4.06Å; F124-R128 HydrophobicContact CD2-CG 3.94Å; F124-R128 VanDerWaalsContact CD2-NH1 3.26Å; F124-R128 HydrophobicContact CE1-CG 3.77Å; F124-R128 HydrophobicContact CE2-CG 3.65Å; F124-R128 HydrophobicContact CG-CG 4.14Å; F124-R128 HydrophobicContact CZ-CG 3.57Å; F124-R128 VanDerWaalsContact O-CB 3.31Å; F124-R128 WeakPolarHBondContact O-CB 3.38Å; F124-R128 WeakPolarHBondContact O-CG 3.31Å; F124-R128 PolarHBondContact O-N 2.88Å; F124-I184 HydrophobicContact CE1-CG1 4.23Å; F124-I184 HydrophobicContact CZ-CG1 4.37Å; F124-Y187 HydrophobicContact CD2-CE2 4.34Å; F124-Y187 AromaticContact CE2-CD2 3.7Å; F124-Y187 HydrophobicContact CE2-CD2 3.7Å; F124-Y187 AromaticContact CE2-CE2 3.54Å; F124-Y187 HydrophobicContact CE2-CE2 3.54Å; F124-Y187 AromaticContact CZ-CD2 3.99Å; F124-Y187 HydrophobicContact CZ-CD2 3.99Å; F124-Y187 HydrophobicContact CZ-CE2 4.25Å; F124-W191 AromaticContact CD1-CH2 3.6Å; F124-W191 HydrophobicContact CD1-CH2 3.6Å; F124-W191 AromaticContact CD1-CZ3 3.81Å; F124-W191 HydrophobicContact CD1-CZ3 3.81Å; F124-W191 AromaticContact CE1-CH2 3.36Å; F124-W191 HydrophobicContact CE1-CH2 3.36Å; F124-W191 HydrophobicContact CE1-CZ2 4.36Å; F124-W191 AromaticContact CE1-CZ3 3.61Å; F124-W191 HydrophobicContact CE1-CZ3 3.61Å; F124-W191 HydrophobicContact CZ-CH2 4.4Å; F124-W191 HydrophobicContact CZ-CZ3 4.33Å
125	Y	93.2	Very high	92.6	Very high	20 Å²	20	28.9 Å²	28.9	8%	0.078	15%	0.154	C	C	.	.	H	α-helix	trans	-59.8	-43.7	178.8	-90.7	-95.4	0	0	0	111.8	V121 L122 H123 N129 W191 L198 E246	V121-Y125 HydrophobicContact CG1-CD2 3.8Å; V121-Y125 HydrophobicContact CG1-CE2 3.84Å; V121-Y125 WeakPolarHBondContact O-CD2 3.3Å; V121-Y125 PolarHBondContact O-N 3.43Å; L122-Y125 PolarHBondContact O-N 2.85Å; H123-Y125 PolarHBondContact O-N 3.16Å; Y125-N129 WeakPolarHBondContact O-CB 3.09Å; Y125-N129 PolarHBondContact O-N 3.38Å; Y125-N129 PolarHBondContact O-ND2 3.11Å; Y125-N129 PolarHBondContact O-OD1 3.29Å; Y125-W191 HydrophobicContact CD2-CH2 4.1Å; Y125-W191 AromaticContact CE2-CH2 3.38Å; Y125-W191 HydrophobicContact CE2-CH2 3.38Å; Y125-W191 AromaticContact CE2-CZ2 3.59Å; Y125-W191 HydrophobicContact CE2-CZ2 3.59Å; Y125-W191 AromaticContact CZ-CH2 3.85Å; Y125-W191 AromaticContact CZ-CZ2 3.56Å; Y125-W191 WeakPolarHBondContact OH-CZ2 3.5Å; Y125-L198 HydrophobicContact CD2-CD1 4.28Å; Y125-L198 HydrophobicContact CE2-CD1 3.45Å; Y125-L198 VanDerWaalsContact CE2-CD1 3.45Å; Y125-E246 PolarHBondContact OH-OE1 2.78Å; Y125-E246 VanDerWaalsContact OH-OE1 3.1Å
126	A	92.6	Very high	92.9	Very high	48 Å²	48	24.8 Å²	24.8	40%	0.397	14%	0.135	S	C	.	.	H	α-helix	trans	-63	-50.7	-179.5	0	0	0	0	0	111.2	L122 H123 F124 R128 N129 Q130 M210	L122-A126 WeakPolarHBondContact O-CB 3.35Å; L122-A126 PolarHBondContact O-N 3.08Å; H123-A126 PolarHBondContact O-N 3.15Å; F124-A126 VanDerWaalsContact C-N 3.34Å; F124-A126 PolarHBondContact O-N 3.46Å; A126-R128 PolarHBondContact O-N 3.23Å; A126-N129 PolarHBondContact O-N 3.4Å; A126-Q130 PolarHBondContact O-N 2.84Å; A126-M210 HydrophobicContact CB-CE 3.81Å
127	T	93.7	Very high	92.9	Very high	27 Å²	27	28.9 Å²	28.9	17%	0.166	15%	0.152	C	C	.	.	H	α-helix	trans	-64.1	-42.9	179.9	-57.1	0	0	0	0	111.7	H123 F124 Q130 Q131	H123-T127 PolarHBondContact CE1-OG1 2.98Å; H123-T127 WeakPolarHBondContact O-CB 3.46Å; H123-T127 PolarHBondContact O-N 3.06Å; H123-T127 PolarHBondContact O-OG1 3.16Å; F124-T127 PolarHBondContact O-N 3.03Å; T127-Q130 PolarHBondContact O-N 3.4Å; T127-Q131 WeakPolarHBondContact O-CB 3.4Å; T127-Q131 VanDerWaalsContact O-CG 3.29Å; T127-Q131 WeakPolarHBondContact O-CG 3.4Å; T127-Q131 PolarHBondContact O-N 3.43Å
128	R	95.1	Very high	92.9	Very high	15 Å²	15	33.7 Å²	33.7	6%	0.057	17%	0.172	C	C	.	.	H	α-helix	trans	-67.9	-34.8	177.5	-64	-54.4	92.2	96.1	-5.7	112.1	E79 F124 A126 L132 L183	E79-R128 IonicContact OE1-CZ 3.77Å; E79-R128 IonicContact OE1-NH2 3.78Å; E79-R128 PolarHBondContact OE1-NH2 3.4Å; E79-R128 IonicContact OE2-NH2 3.29Å; F124-R128 HydrophobicContact CD1-CG 4.06Å; F124-R128 HydrophobicContact CD2-CG 3.94Å; F124-R128 VanDerWaalsContact CD2-NH1 3.26Å; F124-R128 HydrophobicContact CE1-CG 3.77Å; F124-R128 HydrophobicContact CE2-CG 3.65Å; F124-R128 HydrophobicContact CG-CG 4.14Å; F124-R128 HydrophobicContact CZ-CG 3.57Å; F124-R128 VanDerWaalsContact O-CB 3.31Å; F124-R128 WeakPolarHBondContact O-CB 3.38Å; F124-R128 WeakPolarHBondContact O-CG 3.31Å; F124-R128 PolarHBondContact O-N 2.88Å; A126-R128 PolarHBondContact O-N 3.23Å; R128-L132 PolarHBondContact O-N 2.86Å; R128-L183 HydrophobicContact CB-CD1 4.04Å; R128-L183 HydrophobicContact CG-CB 4.29Å; R128-L183 HydrophobicContact CG-CD1 4.38Å
129	N	94.6	Very high	92.6	Very high	19 Å²	19	35.4 Å²	35.4	10%	0.102	18%	0.178	C	C	.	.	H	α-helix	trans	-67.8	-41.2	174.7	-70.6	-0.1	0	0	0	111.2	Y125 A126 L132 A133 R180 M210	Y125-N129 WeakPolarHBondContact O-CB 3.09Å; Y125-N129 PolarHBondContact O-N 3.38Å; Y125-N129 PolarHBondContact O-ND2 3.11Å; Y125-N129 PolarHBondContact O-OD1 3.29Å; A126-N129 PolarHBondContact O-N 3.4Å; N129-L132 PolarHBondContact O-N 2.92Å; N129-A133 PolarHBondContact O-N 2.89Å; N129-R180 PolarHBondContact OD1-NE 3.39Å; N129-R180 PolarHBondContact OD1-NH2 3.12Å; N129-M210 PolarHBondContact ND2-O 3.15Å
130	Q	93.4	Very high	92	Very high	118 Å²	118	37.8 Å²	37.8	55%	0.551	19%	0.185	S	C	*	.	H	α-helix	trans	-62.6	-46	173.6	-176.3	-176.4	-21.2	0	0	111.6	A126 T127 L132 A133 E134	A126-Q130 PolarHBondContact O-N 2.84Å; T127-Q130 PolarHBondContact O-N 3.4Å; Q130-L132 VanDerWaalsContact C-N 3.28Å; Q130-L132 PolarHBondContact O-N 3.36Å; Q130-A133 WeakPolarHBondContact O-CB 3.4Å; Q130-A133 PolarHBondContact O-N 3.02Å; Q130-E134 PolarHBondContact NE2-OE1 3.39Å; Q130-E134 WeakPolarHBondContact O-CG 3.47Å; Q130-E134 PolarHBondContact O-N 2.93Å
131	Q	94.7	Very high	91.5	Very high	57 Å²	57	41.5 Å²	41.5	27%	0.266	21%	0.208	S	C	.	.	H	α-helix	trans	-57.9	-41.1	175.3	-76.2	175.1	-14.2	0	0	111.9	T127 E134 V135	T127-Q131 WeakPolarHBondContact O-CB 3.4Å; T127-Q131 VanDerWaalsContact O-CG 3.29Å; T127-Q131 WeakPolarHBondContact O-CG 3.4Å; T127-Q131 PolarHBondContact O-N 3.43Å; Q131-E134 PolarHBondContact O-N 3.31Å; Q131-V135 WeakPolarHBondContact O-CB 3.31Å; Q131-V135 VanDerWaalsContact O-CG2 3.26Å; Q131-V135 WeakPolarHBondContact O-CG2 3.27Å; Q131-V135 PolarHBondContact O-N 3.32Å
132	L	94	Very high	90.9	Very high	1 Å²	1	45 Å²	45	1%	0.005	23%	0.23	C	C	.	.	H	α-helix	trans	-61.9	-43.7	174.2	177.3	70.4	0	0	0	111.3	R128 N129 Q130 E134 V135 M136 Y179 R180 L214 I218	R128-L132 PolarHBondContact O-N 2.86Å; N129-L132 PolarHBondContact O-N 2.92Å; Q130-L132 VanDerWaalsContact C-N 3.28Å; Q130-L132 PolarHBondContact O-N 3.36Å; L132-E134 PolarHBondContact O-N 3.44Å; L132-V135 PolarHBondContact O-N 3.49Å; L132-M136 HydrophobicContact CD1-CE 4.38Å; L132-M136 HydrophobicContact CD1-CG 4.16Å; L132-M136 HydrophobicContact CD1-SD 4.24Å; L132-M136 HydrophobicContact CD2-CE 4Å; L132-M136 HydrophobicContact CG-CE 3.65Å; L132-M136 HydrophobicContact CG-CG 4.36Å; L132-M136 HydrophobicContact CG-SD 4.14Å; L132-M136 WeakPolarHBondContact O-CB 3.49Å; L132-M136 VanDerWaalsContact O-CG 3.29Å; L132-M136 WeakPolarHBondContact O-CG 3.33Å; L132-M136 PolarHBondContact O-N 3.38Å; L132-Y179 HydrophobicContact CB-CD1 4.44Å; L132-Y179 HydrophobicContact CD1-CD1 3.54Å; L132-Y179 HydrophobicContact CD1-CE1 4.38Å; L132-Y179 HydrophobicContact CD1-CG 4.26Å; L132-R180 HydrophobicContact CD2-CB 4.15Å; L132-R180 HydrophobicContact CD2-CG 4.44Å; L132-L214 HydrophobicContact CD2-CD1 3.35Å; L132-I218 HydrophobicContact CD2-CD1 4.25Å; L132-I218 HydrophobicContact CD2-CG1 4.14Å
133	A	92.7	Very high	90.1	Very high	15 Å²	15	47 Å²	47	12%	0.124	25%	0.246	C	C	.	.	H	α-helix	trans	-59.8	-45.5	177.6	0	0	0	0	0	111.9	N129 Q130 V135 M136 Q137 E217	N129-A133 PolarHBondContact O-N 2.89Å; Q130-A133 WeakPolarHBondContact O-CB 3.4Å; Q130-A133 PolarHBondContact O-N 3.02Å; A133-V135 PolarHBondContact O-N 2.88Å; A133-M136 PolarHBondContact O-N 3.26Å; A133-Q137 VanDerWaalsContact O-CG 3.28Å; A133-Q137 WeakPolarHBondContact O-CG 3.25Å; A133-Q137 PolarHBondContact O-N 3.2Å; A133-E217 HydrophobicContact CB-CG 3.89Å
134	E	93.5	Very high	88.9	Confident	84 Å²	84	48.5 Å²	48.5	39%	0.393	25%	0.253	S	S	.	.	H	α-helix	trans	-61.1	-44.7	176.7	-69.7	170.4	-168.8	0	0	111.7	Q130 Q131 L132 Q137 Q138	Q130-E134 PolarHBondContact NE2-OE1 3.39Å; Q130-E134 WeakPolarHBondContact O-CG 3.47Å; Q130-E134 PolarHBondContact O-N 2.93Å; Q131-E134 PolarHBondContact O-N 3.31Å; L132-E134 PolarHBondContact O-N 3.44Å; E134-Q137 WeakPolarHBondContact O-CB 3.48Å; E134-Q137 PolarHBondContact O-N 3Å; E134-Q138 WeakPolarHBondContact O-CG 3.27Å; E134-Q138 PolarHBondContact O-N 3.44Å
135	V	92.9	Very high	87.4	Confident	20 Å²	20	51.2 Å²	51.2	12%	0.121	27%	0.272	C	S	.	.	H	α-helix	trans	-67.3	-38.5	178.8	169	0	0	0	0	111.9	Q131 L132 A133 Q137 Q138 W139 Y179	Q131-V135 WeakPolarHBondContact O-CB 3.31Å; Q131-V135 VanDerWaalsContact O-CG2 3.26Å; Q131-V135 WeakPolarHBondContact O-CG2 3.27Å; Q131-V135 PolarHBondContact O-N 3.32Å; L132-V135 PolarHBondContact O-N 3.49Å; A133-V135 PolarHBondContact O-N 2.88Å; V135-Q137 VanDerWaalsContact C-N 3.34Å; V135-Q138 WeakPolarHBondContact O-CB 3.39Å; V135-Q138 PolarHBondContact O-N 3.29Å; V135-W139 HydrophobicContact CG1-CD2 4.27Å; V135-W139 HydrophobicContact CG1-CH2 4.18Å; V135-W139 HydrophobicContact CG1-CZ2 3.37Å; V135-W139 VanDerWaalsContact O-CD1 3.28Å; V135-W139 VanDerWaalsContact O-CG 3.3Å; V135-W139 PolarHBondContact O-N 3.45Å; V135-Y179 HydrophobicContact CB-CE1 4.26Å; V135-Y179 HydrophobicContact CG1-CD2 4.37Å; V135-Y179 HydrophobicContact CG1-CE1 4.33Å; V135-Y179 HydrophobicContact CG1-CE2 4.14Å; V135-Y179 HydrophobicContact CG2-CE1 4.12Å; V135-Y179 HydrophobicContact CG2-CE2 4.39Å
136	M	90.4	Very high	86.2	Confident	0 Å²	0	54.7 Å²	54.7	0%	0	29%	0.291	C	S	.	.	H	α-helix	trans	-66.3	-36.3	174.7	-72.3	-172.4	-63.7	0	0	112	L132 A133 W139 R140 F172 E217 I218 Q221	L132-M136 HydrophobicContact CD1-CE 4.38Å; L132-M136 HydrophobicContact CD1-CG 4.16Å; L132-M136 HydrophobicContact CD1-SD 4.24Å; L132-M136 HydrophobicContact CD2-CE 4Å; L132-M136 HydrophobicContact CG-CE 3.65Å; L132-M136 HydrophobicContact CG-CG 4.36Å; L132-M136 HydrophobicContact CG-SD 4.14Å; L132-M136 WeakPolarHBondContact O-CB 3.49Å; L132-M136 VanDerWaalsContact O-CG 3.29Å; L132-M136 WeakPolarHBondContact O-CG 3.33Å; L132-M136 PolarHBondContact O-N 3.38Å; A133-M136 PolarHBondContact O-N 3.26Å; M136-W139 HydrophobicContact CG-CE3 4.02Å; M136-W139 HydrophobicContact CG-CZ3 3.9Å; M136-W139 PolarHBondContact O-N 3.32Å; M136-R140 PolarHBondContact O-N 3.3Å; M136-F172 HydrophobicContact CG-CZ 4.38Å; M136-F172 HydrophobicContact SD-CE1 4.49Å; M136-F172 HydrophobicContact SD-CZ 3.89Å; M136-E217 HydrophobicContact CE-CG 3.82Å; M136-I218 HydrophobicContact CE-CG1 4.23Å; M136-I218 HydrophobicContact SD-CG1 4.21Å; M136-Q221 HydrophobicContact CB-CB 4.33Å; M136-Q221 HydrophobicContact CB-CG 3.86Å; M136-Q221 HydrophobicContact CE-CG 3.76Å; M136-Q221 HydrophobicContact SD-CB 4.14Å; M136-Q221 HydrophobicContact SD-CG 3.98Å
137	Q	87.9	Confident	84.7	Confident	95 Å²	95	55.6 Å²	55.6	44%	0.444	29%	0.289	S	S	.	.	H	α-helix	trans	-63	-42.3	172.2	-72.2	174.2	11.4	0	0	111.7	A133 E134 V135 W139 R140 T141	A133-Q137 VanDerWaalsContact O-CG 3.28Å; A133-Q137 WeakPolarHBondContact O-CG 3.25Å; A133-Q137 PolarHBondContact O-N 3.2Å; E134-Q137 WeakPolarHBondContact O-CB 3.48Å; E134-Q137 PolarHBondContact O-N 3Å; V135-Q137 VanDerWaalsContact C-N 3.34Å; Q137-W139 VanDerWaalsContact C-N 3.33Å; Q137-W139 PolarHBondContact O-N 3.42Å; Q137-R140 WeakPolarHBondContact O-CB 3.39Å; Q137-R140 PolarHBondContact O-N 2.9Å; Q137-T141 PolarHBondContact O-N 3.07Å
138	Q	89.7	Confident	83.2	Confident	110 Å²	110	61.5 Å²	61.5	51%	0.514	31%	0.312	S	S	.	.	H	α-helix	trans	-63.1	-37.5	175.6	-69.8	169.9	6.1	0	0	112.4	E134 V135 R140 T141 T142	E134-Q138 WeakPolarHBondContact O-CG 3.27Å; E134-Q138 PolarHBondContact O-N 3.44Å; V135-Q138 WeakPolarHBondContact O-CB 3.39Å; V135-Q138 PolarHBondContact O-N 3.29Å; Q138-R140 VanDerWaalsContact C-N 3.28Å; Q138-R140 PolarHBondContact O-N 3.32Å; Q138-T141 WeakPolarHBondContact CA-OG1 3.41Å; Q138-T141 PolarHBondContact O-N 2.79Å; Q138-T141 PolarHBondContact O-OG1 2.84Å; Q138-T141 VanDerWaalsContact O-OG1 3.05Å; Q138-T142 VanDerWaalsContact O-CB 3.3Å; Q138-T142 WeakPolarHBondContact O-CB 3.42Å; Q138-T142 PolarHBondContact O-N 3.19Å; Q138-T142 PolarHBondContact O-OG1 3.1Å
139	W	86.9	Confident	81.5	Confident	40 Å²	40	67.8 Å²	67.8	15%	0.152	35%	0.347	C	S	.	.	H	α-helix	trans	-61.3	-39.7	174.6	-63.2	-12.1	0	0	0	111.2	V135 M136 Q137 S143 F172 R175 Y179	V135-W139 HydrophobicContact CG1-CD2 4.27Å; V135-W139 HydrophobicContact CG1-CH2 4.18Å; V135-W139 HydrophobicContact CG1-CZ2 3.37Å; V135-W139 VanDerWaalsContact O-CD1 3.28Å; V135-W139 VanDerWaalsContact O-CG 3.3Å; V135-W139 PolarHBondContact O-N 3.45Å; M136-W139 HydrophobicContact CG-CE3 4.02Å; M136-W139 HydrophobicContact CG-CZ3 3.9Å; M136-W139 PolarHBondContact O-N 3.32Å; Q137-W139 VanDerWaalsContact C-N 3.33Å; Q137-W139 PolarHBondContact O-N 3.42Å; W139-S143 WeakPolarHBondContact O-CB 3.21Å; W139-S143 PolarHBondContact O-N 3.28Å; W139-S143 PolarHBondContact O-OG 3.31Å; W139-F172 HydrophobicContact CE3-CE2 4.3Å; W139-R175 VanDerWaalsContact CD1-NH2 3.29Å; W139-R175 VanDerWaalsContact CE2-NE 3.27Å; W139-R175 HydrophobicContact CH2-CB 4.44Å; W139-R175 HydrophobicContact CH2-CG 3.6Å; W139-R175 HydrophobicContact CZ2-CG 4.06Å; W139-R175 VanDerWaalsContact CZ2-NE 3.34Å; W139-R175 HydrophobicContact CZ3-CB 4.38Å; W139-R175 HydrophobicContact CZ3-CG 3.85Å; W139-Y179 HydrophobicContact CZ2-CD2 4.47Å
140	R	79.4	Confident	80	Confident	74 Å²	74	72.6 Å²	72.6	28%	0.279	37%	0.372	S	S	.	.	H	α-helix	trans	-65.1	-49	174.9	-73.7	-168.3	-72.9	131.6	-7.3	112.6	M136 Q137 Q138 T142 S143 E144	M136-R140 PolarHBondContact O-N 3.3Å; Q137-R140 WeakPolarHBondContact O-CB 3.39Å; Q137-R140 PolarHBondContact O-N 2.9Å; Q138-R140 VanDerWaalsContact C-N 3.28Å; Q138-R140 PolarHBondContact O-N 3.32Å; R140-T142 VanDerWaalsContact C-N 3.31Å; R140-T142 PolarHBondContact O-N 3.01Å; R140-S143 PolarHBondContact O-N 2.92Å; R140-E144 WeakPolarHBondContact O-CG 3.3Å; R140-E144 PolarHBondContact O-N 3.02Å
141	T	82.3	Confident	77.9	Confident	79 Å²	79	73.2 Å²	73.2	49%	0.485	38%	0.378	S	S	.	.	H	α-helix	trans	-65.2	-35.8	-179.7	58.3	0	0	0	0	112.3	Q137 Q138 E144 S145	Q137-T141 PolarHBondContact O-N 3.07Å; Q138-T141 WeakPolarHBondContact CA-OG1 3.41Å; Q138-T141 PolarHBondContact O-N 2.79Å; Q138-T141 PolarHBondContact O-OG1 2.84Å; Q138-T141 VanDerWaalsContact O-OG1 3.05Å; T141-E144 PolarHBondContact O-N 3.38Å; T141-S145 PolarHBondContact O-N 2.9Å
142	T	82.1	Confident	76	Confident	73 Å²	73	77.5 Å²	77.5	45%	0.448	40%	0.402	S	S	.	.	H	α-helix	trans	-64.4	-47.5	175.1	-55.3	0	0	0	0	110.5	Q138 R140 E144 S145 I146	Q138-T142 VanDerWaalsContact O-CB 3.3Å; Q138-T142 WeakPolarHBondContact O-CB 3.42Å; Q138-T142 PolarHBondContact O-N 3.19Å; Q138-T142 PolarHBondContact O-OG1 3.1Å; R140-T142 VanDerWaalsContact C-N 3.31Å; R140-T142 PolarHBondContact O-N 3.01Å; T142-E144 VanDerWaalsContact C-N 3.31Å; T142-E144 PolarHBondContact O-N 3.42Å; T142-S145 PolarHBondContact O-N 2.8Å; T142-S145 PolarHBondContact O-OG 3.11Å; T142-I146 HydrophobicContact CG2-CD1 4.2Å; T142-I146 WeakPolarHBondContact O-CG1 3.31Å; T142-I146 PolarHBondContact O-N 3.46Å; T142-I146 VanDerWaalsContact O-N 3.08Å
143	S	74.9	Confident	73.5	Confident	65 Å²	65	87 Å²	87	46%	0.455	44%	0.443	S	S	.	.	H	α-helix	trans	-59.5	-39.4	174.3	-69.3	0	0	0	0	112.6	W139 R140 I146 N147	W139-S143 WeakPolarHBondContact O-CB 3.21Å; W139-S143 PolarHBondContact O-N 3.28Å; W139-S143 PolarHBondContact O-OG 3.31Å; R140-S143 PolarHBondContact O-N 2.92Å; S143-I146 PolarHBondContact O-N 2.83Å; S143-N147 PolarHBondContact O-N 3.2Å
144	E	67.4	Low	70.9	Confident	58 Å²	58	89.7 Å²	89.7	27%	0.271	47%	0.472	S	S	.	.	H	α-helix	trans	-66.2	-38	175.2	-72.7	175.7	-172.3	0	0	112.8	R140 T141 T142 N147 K148	R140-E144 WeakPolarHBondContact O-CG 3.3Å; R140-E144 PolarHBondContact O-N 3.02Å; T141-E144 PolarHBondContact O-N 3.38Å; T142-E144 VanDerWaalsContact C-N 3.31Å; T142-E144 PolarHBondContact O-N 3.42Å; E144-N147 PolarHBondContact O-N 3.06Å; E144-K148 WeakPolarHBondContact O-CB 3.49Å; E144-K148 VanDerWaalsContact O-CG 3.32Å; E144-K148 WeakPolarHBondContact O-CG 3.35Å; E144-K148 PolarHBondContact O-N 3.32Å
145	S	63.4	Low	68.3	Low	57 Å²	57	90.7 Å²	90.7	40%	0.399	49%	0.488	S	S	.	.	H	α-helix	trans	-67.7	-37.3	178.1	72.5	0	0	0	0	112.5	T141 T142 K148 N149	T141-S145 PolarHBondContact O-N 2.9Å; T142-S145 PolarHBondContact O-N 2.8Å; T142-S145 PolarHBondContact O-OG 3.11Å; S145-K148 PolarHBondContact O-N 2.92Å; S145-N149 PolarHBondContact O-N 2.9Å; S145-N149 PolarHBondContact O-ND2 3.24Å
146	I	68.6	Low	65.5	Low	94 Å²	94	96.8 Å²	96.8	48%	0.482	52%	0.52	S	S	.	.	H	α-helix	trans	-64.5	-44.8	175.7	-67.8	167.1	0	0	0	109.7	T142 S143 N149 I150	T142-I146 HydrophobicContact CG2-CD1 4.2Å; T142-I146 WeakPolarHBondContact O-CG1 3.31Å; T142-I146 PolarHBondContact O-N 3.46Å; T142-I146 VanDerWaalsContact O-N 3.08Å; S143-I146 PolarHBondContact O-N 2.83Å; I146-N149 PolarHBondContact O-N 3.43Å; I146-I150 HydrophobicContact CG2-CD1 4.28Å; I146-I150 WeakPolarHBondContact O-CG1 3.46Å
147	N	62	Low	62.9	Low	67 Å²	67	102.5 Å²	102.5	36%	0.358	56%	0.56	S	S	.	*	H	α-helix	trans	-66.8	-42	178.9	-68.4	-11.6	0	0	0	112	S143 E144 N149 I150 D151	S143-N147 PolarHBondContact O-N 3.2Å; E144-N147 PolarHBondContact O-N 3.06Å; N147-N149 VanDerWaalsContact C-N 3.27Å; N147-N149 PolarHBondContact O-N 3.29Å; N147-I150 PolarHBondContact O-N 3.35Å; N147-D151 PolarHBondContact O-N 3.16Å
148	K	60.5	Low	60.3	Low	151 Å²	151	103.8 Å²	103.8	66%	0.657	58%	0.577	S	S	*	*	H	α-helix	trans	-62.7	-29.8	177.8	-76.2	172.8	-176.1	168	0	113.9	E144 S145 I150	E144-K148 WeakPolarHBondContact O-CB 3.49Å; E144-K148 VanDerWaalsContact O-CG 3.32Å; E144-K148 WeakPolarHBondContact O-CG 3.35Å; E144-K148 PolarHBondContact O-N 3.32Å; S145-K148 PolarHBondContact O-N 2.92Å; K148-I150 VanDerWaalsContact C-N 3.25Å; K148-I150 PolarHBondContact O-N 3.46Å
149	N	59.5	Low	57.9	Low	147 Å²	147	106.1 Å²	106.1	79%	0.786	59%	0.592	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76.5	-12.3	176.5	-76.4	-23.1	0	0	0	113.3	S145 I146 N147	S145-N149 PolarHBondContact O-N 2.9Å; S145-N149 PolarHBondContact O-ND2 3.24Å; I146-N149 PolarHBondContact O-N 3.43Å; N147-N149 VanDerWaalsContact C-N 3.27Å; N147-N149 PolarHBondContact O-N 3.29Å
150	I	63.7	Low	56.2	Low	120 Å²	120	105.5 Å²	105.5	62%	0.615	59%	0.594	S	S	*	*	T	Hydrogen-bonded Turn	trans	-97.5	-21.1	-178.8	-66.1	169.9	0	0	0	111.8	I146 N147 K148 I152	I146-I150 HydrophobicContact CG2-CD1 4.28Å; I146-I150 WeakPolarHBondContact O-CG1 3.46Å; N147-I150 PolarHBondContact O-N 3.35Å; K148-I150 VanDerWaalsContact C-N 3.25Å; K148-I150 PolarHBondContact O-N 3.46Å; I150-I152 PolarHBondContact O-N 2.89Å
151	D	50.3	Low	55.4	Low	130 Å²	130	106.9 Å²	106.9	70%	0.695	61%	0.611	S	S	*	*			trans	-85.3	85.1	-170	-71.1	-25.5	0	0	0	114.5	N147	N147-D151 PolarHBondContact O-N 3.16Å
152	I	53.4	Low	54.8	Low	148 Å²	148	106.6 Å²	106.6	76%	0.759	60%	0.603	S	S	*	*			trans	-81	108.1	151.4	-64.6	174.9	0	0	0	107.8	I150	I150-I152 PolarHBondContact O-N 2.89Å
153	K	42.6	Very low	54.3	Low	201 Å²	201	104.4 Å²	104.4	87%	0.874	59%	0.59	S	S	*	*	S	Bend	trans	76.1	114.2	163.6	-59.2	169.9	-179.2	-178.2	0	117.9
154	G	38.4	Very low	54.1	Low	71 Å²	71	106 Å²	106	73%	0.732	60%	0.601	S	S	*	*			trans	123.8	104.9	134.5	0	0	0	0	0	117.3
155	S	37.6	Very low	54.7	Low	104 Å²	104	106.5 Å²	106.5	73%	0.727	61%	0.608	S	S	*	*			trans	58.4	110.2	151.1	72.5	0	0	0	0	120.4
156	D	34.3	Very low	55.5	Low	149 Å²	149	106.7 Å²	106.7	80%	0.797	61%	0.613	S	S	*	*				63.3	72.8	123.4	-49.8	-15.3	0	0	0	119.2
157	S	35.7	Very low	56.1	Low	119 Å²	119	105 Å²	105	83%	0.832	61%	0.614	S	S	*	*				-174.1	101.1	127.1	-86.1	0	0	0	0	110.2	L159	S157-L159 PolarHBondContact O-N 3.49Å
158	P	33.6	Very low	57.2	Low	122 Å²	122	105.6 Å²	105.6	79%	0.792	61%	0.614	S	S	*	*			trans	-92.6	89.6	-175	34.4	-27.2	0	0	0	109
159	L	40.2	Very low	58.4	Low	159 Å²	159	100.7 Å²	100.7	83%	0.832	59%	0.594	S	S	*	*	S	Bend	trans	-168.2	110.4	164.7	-134.8	62.1	0	0	0	113	S157	S157-L159 PolarHBondContact O-N 3.49Å
160	S	51.1	Low	59.8	Low	27 Å²	27	94.5 Å²	94.5	19%	0.189	56%	0.561	C	S	.	*			trans	49	90.8	151	175.3	0	0	0	0	115.9	F162	S160-F162 VanDerWaalsContact C-N 3.3Å; S160-F162 VanDerWaalsContact O-CD2 3.26Å; S160-F162 WeakPolarHBondContact O-CD2 3.3Å; S160-F162 PolarHBondContact O-N 3.45Å; S160-F162 WeakPolarHBondContact OG-CD2 3.27Å; S160-F162 WeakPolarHBondContact OG-CE2 3.48Å; S160-F162 WeakPolarHBondContact OG-CZ 3.39Å
161	T	62.2	Low	61	Low	104 Å²	104	95.3 Å²	95.3	64%	0.638	56%	0.563	S	S	*	*			trans	-69.2	90.1	172.1	-45.5	0	0	0	0	109.8
162	F	69.4	Low	62.9	Low	72 Å²	72	90.6 Å²	90.6	32%	0.316	54%	0.536	S	S	.	.			trans	-67.1	149.9	166.3	-68.1	-74.2	0	0	0	109.8	S160 S164 Q221 G223	S160-F162 VanDerWaalsContact C-N 3.3Å; S160-F162 VanDerWaalsContact O-CD2 3.26Å; S160-F162 WeakPolarHBondContact O-CD2 3.3Å; S160-F162 PolarHBondContact O-N 3.45Å; S160-F162 WeakPolarHBondContact OG-CD2 3.27Å; S160-F162 WeakPolarHBondContact OG-CE2 3.48Å; S160-F162 WeakPolarHBondContact OG-CZ 3.39Å; F162-S164 PolarHBondContact O-N 2.75Å; F162-S164 VanDerWaalsContact O-N 3.1Å; F162-Q221 WeakPolarHBondContact CD1-O 3.45Å; F162-G223 VanDerWaalsContact CD1-N 3.32Å; F162-G223 VanDerWaalsContact CE1-CA 3.42Å
163	P	71.9	Confident	64.8	Low	27 Å²	27	83.9 Å²	83.9	18%	0.175	50%	0.501	C	S	.	.			trans	-57.3	119.4	173.5	25.6	-33.9	0	0	0	109.2	E168 I169 F172 A222	P163-E168 HydrophobicContact CB-CB 3.75Å; P163-I169 HydrophobicContact CB-CG1 3.98Å; P163-I169 HydrophobicContact CG-CG1 4.16Å; P163-F172 HydrophobicContact CG-CB 4.44Å; P163-F172 HydrophobicContact CG-CG 4.47Å; P163-A222 HydrophobicContact CG-CB 4.33Å
164	S	70.1	Confident	67.2	Low	98 Å²	98	75.9 Å²	75.9	69%	0.685	47%	0.466	S	S	*	.			trans	-102.9	-34.1	-171.6	66.6	0	0	0	0	111.6	F162 E168	F162-S164 PolarHBondContact O-N 2.75Å; F162-S164 VanDerWaalsContact O-N 3.1Å; S164-E168 PolarHBondContact N-OE2 2.92Å; S164-E168 PolarHBondContact OG-OE2 3.13Å
165	T	80.2	Confident	69.8	Low	69 Å²	69	78.4 Å²	78.4	42%	0.423	45%	0.454	S	S	.	.	S	Bend	trans	-83.1	144.4	178.6	-50.5	0	0	0	0	110.3	A167 E168 I169	T165-A167 VanDerWaalsContact C-N 3.26Å; T165-A167 HydrophobicContact CG2-CB 4.34Å; T165-A167 PolarHBondContact O-N 3.38Å; T165-E168 VanDerWaalsContact CB-CD 3.47Å; T165-E168 WeakPolarHBondContact CB-OE1 3.21Å; T165-E168 PolarHBondContact N-OE2 3.36Å; T165-E168 WeakPolarHBondContact O-CB 3.44Å; T165-E168 PolarHBondContact O-N 2.91Å; T165-E168 PolarHBondContact OG1-OE1 3.22Å; T165-I169 PolarHBondContact O-N 3.4Å
166	A	80.3	Confident	72.5	Confident	61 Å²	61	73.5 Å²	73.5	50%	0.504	42%	0.419	S	S	.	.	H	α-helix	trans	-51.5	-47.2	175.7	0	0	0	0	0	111.8	E168 I169 D170	A166-E168 VanDerWaalsContact C-N 3.31Å; A166-E168 PolarHBondContact O-N 2.97Å; A166-I169 WeakPolarHBondContact O-CB 3.17Å; A166-I169 PolarHBondContact O-N 3.22Å; A166-I169 VanDerWaalsContact O-N 3.1Å; A166-D170 VanDerWaalsContact C-OD2 3.24Å; A166-D170 PolarHBondContact O-N 3.48Å
167	A	81.9	Confident	75.4	Confident	60 Å²	60	66.5 Å²	66.5	50%	0.496	38%	0.381	S	S	.	.	H	α-helix	trans	-61.1	-34.5	177.5	0	0	0	0	0	113.8	T165 D170 Q171	T165-A167 VanDerWaalsContact C-N 3.26Å; T165-A167 HydrophobicContact CG2-CB 4.34Å; T165-A167 PolarHBondContact O-N 3.38Å; A167-D170 WeakPolarHBondContact CA-OD2 3.29Å; A167-D170 PolarHBondContact O-N 3.47Å; A167-Q171 WeakPolarHBondContact O-CB 3.47Å; A167-Q171 PolarHBondContact O-N 3.3Å
168	E	84.6	Confident	78.2	Confident	79 Å²	79	62.7 Å²	62.7	37%	0.369	35%	0.35	S	S	.	.	H	α-helix	trans	-68.3	-40.3	175.1	-69.4	160.5	-156.2	0	0	110.8	P163 S164 T165 A166 D170 Q171 F172	P163-E168 HydrophobicContact CB-CB 3.75Å; S164-E168 PolarHBondContact N-OE2 2.92Å; S164-E168 PolarHBondContact OG-OE2 3.13Å; T165-E168 VanDerWaalsContact CB-CD 3.47Å; T165-E168 WeakPolarHBondContact CB-OE1 3.21Å; T165-E168 PolarHBondContact N-OE2 3.36Å; T165-E168 WeakPolarHBondContact O-CB 3.44Å; T165-E168 PolarHBondContact O-N 2.91Å; T165-E168 PolarHBondContact OG1-OE1 3.22Å; A166-E168 VanDerWaalsContact C-N 3.31Å; A166-E168 PolarHBondContact O-N 2.97Å; E168-D170 VanDerWaalsContact C-N 3.34Å; E168-Q171 PolarHBondContact O-N 3.24Å; E168-F172 VanDerWaalsContact O-CB 3.28Å; E168-F172 WeakPolarHBondContact O-CB 3.35Å; E168-F172 PolarHBondContact O-N 3.43Å
169	I	86.4	Confident	81.1	Confident	47 Å²	47	60.3 Å²	60.3	24%	0.241	33%	0.326	C	S	.	.	H	α-helix	trans	-62.6	-44.1	175	-61.8	168.9	0	0	0	109.7	P163 T165 A166 Q171 F172 L173 W219	P163-I169 HydrophobicContact CB-CG1 3.98Å; P163-I169 HydrophobicContact CG-CG1 4.16Å; T165-I169 PolarHBondContact O-N 3.4Å; A166-I169 WeakPolarHBondContact O-CB 3.17Å; A166-I169 PolarHBondContact O-N 3.22Å; A166-I169 VanDerWaalsContact O-N 3.1Å; I169-Q171 PolarHBondContact O-N 3.25Å; I169-F172 PolarHBondContact O-N 2.77Å; I169-L173 HydrophobicContact CG2-CD1 4.01Å; I169-L173 HydrophobicContact CG2-CG 4.24Å; I169-L173 WeakPolarHBondContact O-CB 3.24Å; I169-L173 VanDerWaalsContact O-CG 3.26Å; I169-L173 WeakPolarHBondContact O-CG 3.48Å; I169-L173 PolarHBondContact O-N 3.42Å; I169-W219 HydrophobicContact CG2-CH2 4.4Å; I169-W219 HydrophobicContact CG2-CZ3 4.17Å
170	D	87.9	Confident	83.7	Confident	18 Å²	18	52.8 Å²	52.8	10%	0.096	29%	0.287	C	S	.	.	H	α-helix	trans	-64.2	-41.4	178.4	-57.8	-63.7	0	0	0	112.3	A166 A167 E168 F172 L173 Y174 I268 R272	A166-D170 VanDerWaalsContact C-OD2 3.24Å; A166-D170 PolarHBondContact O-N 3.48Å; A167-D170 WeakPolarHBondContact CA-OD2 3.29Å; A167-D170 PolarHBondContact O-N 3.47Å; E168-D170 VanDerWaalsContact C-N 3.34Å; D170-F172 VanDerWaalsContact C-N 3.34Å; D170-L173 PolarHBondContact O-N 2.87Å; D170-Y174 VanDerWaalsContact O-CB 3.24Å; D170-Y174 WeakPolarHBondContact O-CB 3.31Å; D170-Y174 PolarHBondContact O-N 3.43Å; D170-I268 HydrophobicContact CB-CG2 4.05Å; D170-R272 WeakPolarHBondContact OD1-CD 3.29Å; D170-R272 IonicContact OD1-CZ 2.61Å; D170-R272 IonicContact OD1-NE 2.74Å; D170-R272 PolarHBondContact OD1-NE 2.91Å; D170-R272 IonicContact OD1-NH2 3.11Å; D170-R272 PolarHBondContact OD1-NH2 3.41Å; D170-R272 VanDerWaalsContact OD2-CD 3.27Å; D170-R272 WeakPolarHBondContact OD2-CD 3.43Å; D170-R272 IonicContact OD2-CZ 3.04Å; D170-R272 IonicContact OD2-NE 3.19Å; D170-R272 PolarHBondContact OD2-NE 3.05Å; D170-R272 IonicContact OD2-NH1 3.42Å; D170-R272 PolarHBondContact OD2-NH1 2.96Å; D170-R272 IonicContact OD2-NH2 2.69Å; D170-R272 PolarHBondContact OD2-NH2 2.76Å
171	Q	88.7	Confident	85.7	Confident	137 Å²	137	51.5 Å²	51.5	64%	0.64	28%	0.278	S	S	*	.	H	α-helix	trans	-65.8	-39.4	175.9	-173.8	176.7	6.6	0	0	111.2	A167 E168 I169 R175	A167-Q171 WeakPolarHBondContact O-CB 3.47Å; A167-Q171 PolarHBondContact O-N 3.3Å; E168-Q171 PolarHBondContact O-N 3.24Å; I169-Q171 PolarHBondContact O-N 3.25Å; Q171-R175 VanDerWaalsContact O-CB 3.29Å; Q171-R175 WeakPolarHBondContact O-CB 3.25Å; Q171-R175 PolarHBondContact O-N 3.36Å
172	F	90.9	Very high	87.2	Confident	30 Å²	30	51.1 Å²	51.1	13%	0.132	27%	0.267	C	S	.	.	H	α-helix	trans	-63.3	-50.5	174.7	179.9	-95.3	0	0	0	111.2	M136 W139 P163 E168 I169 D170 Y174 R175 S176 I218 Q221 A222	M136-F172 HydrophobicContact CG-CZ 4.38Å; M136-F172 HydrophobicContact SD-CE1 4.49Å; M136-F172 HydrophobicContact SD-CZ 3.89Å; W139-F172 HydrophobicContact CE3-CE2 4.3Å; P163-F172 HydrophobicContact CG-CB 4.44Å; P163-F172 HydrophobicContact CG-CG 4.47Å; E168-F172 VanDerWaalsContact O-CB 3.28Å; E168-F172 WeakPolarHBondContact O-CB 3.35Å; E168-F172 PolarHBondContact O-N 3.43Å; I169-F172 PolarHBondContact O-N 2.77Å; D170-F172 VanDerWaalsContact C-N 3.34Å; F172-Y174 VanDerWaalsContact C-N 3.33Å; F172-Y174 PolarHBondContact O-N 3.48Å; F172-R175 PolarHBondContact O-N 2.72Å; F172-S176 WeakPolarHBondContact O-CB 3.28Å; F172-S176 PolarHBondContact O-N 3Å; F172-S176 PolarHBondContact O-OG 3.47Å; F172-I218 HydrophobicContact CE1-CG2 4.2Å; F172-I218 WeakPolarHBondContact CE1-O 3.39Å; F172-Q221 HydrophobicContact CE1-CB 4.22Å; F172-Q221 HydrophobicContact CZ-CB 3.62Å; F172-A222 HydrophobicContact CD1-CB 3.86Å; F172-A222 HydrophobicContact CE1-CB 3.84Å
173	L	92.5	Very high	88.4	Confident	7 Å²	7	49.4 Å²	49.4	4%	0.037	26%	0.261	C	S	.	.	H	α-helix	trans	-57.6	-46.2	176.2	-71.6	175.5	0	0	0	111.3	I169 D170 S176 L177 I218 W219 V238 I268	I169-L173 HydrophobicContact CG2-CD1 4.01Å; I169-L173 HydrophobicContact CG2-CG 4.24Å; I169-L173 WeakPolarHBondContact O-CB 3.24Å; I169-L173 VanDerWaalsContact O-CG 3.26Å; I169-L173 WeakPolarHBondContact O-CG 3.48Å; I169-L173 PolarHBondContact O-N 3.42Å; D170-L173 PolarHBondContact O-N 2.87Å; L173-S176 PolarHBondContact O-N 2.94Å; L173-L177 WeakPolarHBondContact O-CB 3.49Å; L173-L177 VanDerWaalsContact O-CG 3.24Å; L173-L177 WeakPolarHBondContact O-CG 3.45Å; L173-L177 PolarHBondContact O-N 3.42Å; L173-I218 HydrophobicContact CD2-CG2 3.63Å; L173-W219 HydrophobicContact CD1-CH2 4.18Å; L173-W219 HydrophobicContact CD1-CZ2 4.34Å; L173-V238 HydrophobicContact CD1-CG2 4.41Å; L173-V238 HydrophobicContact CD2-CG2 4.03Å; L173-I268 HydrophobicContact CB-CD1 4.39Å
174	Y	93.5	Very high	89.4	Confident	34 Å²	34	48.1 Å²	48.1	13%	0.133	25%	0.253	C	S	.	.	H	α-helix	trans	-58	-50.6	176.7	176.7	-89	0	0	0	111.1	D170 F172 S176 L177 E178 L264 R265 I268	D170-Y174 VanDerWaalsContact O-CB 3.24Å; D170-Y174 WeakPolarHBondContact O-CB 3.31Å; D170-Y174 PolarHBondContact O-N 3.43Å; F172-Y174 VanDerWaalsContact C-N 3.33Å; F172-Y174 PolarHBondContact O-N 3.48Å; Y174-S176 PolarHBondContact O-N 3Å; Y174-L177 PolarHBondContact O-N 3.49Å; Y174-E178 HydrophobicContact CE1-CB 4.46Å; Y174-E178 WeakPolarHBondContact CE1-OE2 3.14Å; Y174-E178 WeakPolarHBondContact O-CB 3.38Å; Y174-E178 PolarHBondContact O-N 3.01Å; Y174-L264 HydrophobicContact CD2-CD2 4.02Å; Y174-L264 HydrophobicContact CD2-CG 4.08Å; Y174-L264 HydrophobicContact CE2-CD2 4.07Å; Y174-L264 HydrophobicContact CE2-CG 4.29Å; Y174-R265 HydrophobicContact CD2-CB 4.26Å; Y174-R265 HydrophobicContact CE2-CB 4.11Å; Y174-R265 PolarHBondContact OH-NH2 3.45Å; Y174-I268 HydrophobicContact CD2-CD1 4.27Å
175	R	93.5	Very high	90.5	Very high	124 Å²	124	46.8 Å²	46.8	47%	0.468	24%	0.238	S	C	.	.	H	α-helix	trans	-63.6	-41.5	-178.2	-171.5	-172.6	174.4	164.5	0.1	112.2	W139 Q171 F172 Y179	W139-R175 VanDerWaalsContact CD1-NH2 3.29Å; W139-R175 VanDerWaalsContact CE2-NE 3.27Å; W139-R175 HydrophobicContact CH2-CB 4.44Å; W139-R175 HydrophobicContact CH2-CG 3.6Å; W139-R175 HydrophobicContact CZ2-CG 4.06Å; W139-R175 VanDerWaalsContact CZ2-NE 3.34Å; W139-R175 HydrophobicContact CZ3-CB 4.38Å; W139-R175 HydrophobicContact CZ3-CG 3.85Å; Q171-R175 VanDerWaalsContact O-CB 3.29Å; Q171-R175 WeakPolarHBondContact O-CB 3.25Å; Q171-R175 PolarHBondContact O-N 3.36Å; F172-R175 PolarHBondContact O-N 2.72Å; R175-Y179 WeakPolarHBondContact O-CB 3.46Å; R175-Y179 PolarHBondContact O-N 3.26Å
176	S	93.5	Very high	91.1	Very high	0 Å²	0	47.7 Å²	47.7	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-66.5	-46.3	179	-61.1	0	0	0	0	111.8	F172 L173 Y174 Y179 R180	F172-S176 WeakPolarHBondContact O-CB 3.28Å; F172-S176 PolarHBondContact O-N 3Å; F172-S176 PolarHBondContact O-OG 3.47Å; L173-S176 PolarHBondContact O-N 2.94Å; Y174-S176 PolarHBondContact O-N 3Å; S176-Y179 PolarHBondContact O-N 3.31Å; S176-R180 PolarHBondContact O-N 3.47Å
177	L	94.7	Very high	91.7	Very high	2 Å²	2	46.2 Å²	46.2	1%	0.01	23%	0.226	C	C	.	.	H	α-helix	trans	-67.9	-41.2	178	-67.2	173.9	0	0	0	111.6	L173 Y174 Y179 R180 L181 I218 V238 V241 Y242 L264 I268	L173-L177 WeakPolarHBondContact O-CB 3.49Å; L173-L177 VanDerWaalsContact O-CG 3.24Å; L173-L177 WeakPolarHBondContact O-CG 3.45Å; L173-L177 PolarHBondContact O-N 3.42Å; Y174-L177 PolarHBondContact O-N 3.49Å; L177-Y179 PolarHBondContact O-N 2.89Å; L177-R180 PolarHBondContact O-N 3.3Å; L177-L181 WeakPolarHBondContact O-CB 3.46Å; L177-L181 VanDerWaalsContact O-CG 3.31Å; L177-L181 WeakPolarHBondContact O-CG 3.34Å; L177-L181 PolarHBondContact O-N 3.43Å; L177-I218 HydrophobicContact CD2-CD1 4.03Å; L177-V238 HydrophobicContact CD1-CG1 4.47Å; L177-V238 HydrophobicContact CD2-CG1 4.26Å; L177-V241 HydrophobicContact CD1-CG1 4.14Å; L177-Y242 HydrophobicContact CD2-CD2 3.88Å; L177-Y242 HydrophobicContact CD2-CG 4.4Å; L177-L264 HydrophobicContact CB-CD1 4.13Å; L177-L264 HydrophobicContact CB-CD2 4.13Å; L177-L264 HydrophobicContact CD1-CD1 3.9Å; L177-I268 HydrophobicContact CD1-CD1 4.28Å
178	E	94.3	Very high	92.1	Very high	39 Å²	39	45 Å²	45	18%	0.182	21%	0.211	C	C	.	.	H	α-helix	trans	-57.9	-48.6	174.4	179.4	-175.6	-167.4	0	0	111.1	Y174 R180 L181 K182 W261 L264	Y174-E178 HydrophobicContact CE1-CB 4.46Å; Y174-E178 WeakPolarHBondContact CE1-OE2 3.14Å; Y174-E178 WeakPolarHBondContact O-CB 3.38Å; Y174-E178 PolarHBondContact O-N 3.01Å; E178-R180 VanDerWaalsContact C-N 3.34Å; E178-R180 PolarHBondContact O-N 2.86Å; E178-L181 PolarHBondContact O-N 2.85Å; E178-K182 HydrophobicContact CG-CD 4.13Å; E178-K182 WeakPolarHBondContact O-CB 3.4Å; E178-K182 VanDerWaalsContact O-CG 3.3Å; E178-K182 WeakPolarHBondContact O-CG 3.47Å; E178-K182 PolarHBondContact O-N 3.27Å; E178-K182 VanDerWaalsContact OE1-CE 3.23Å; E178-K182 WeakPolarHBondContact OE1-CE 3.38Å; E178-K182 IonicContact OE1-NZ 2.82Å; E178-K182 PolarHBondContact OE1-NZ 3.49Å; E178-W261 HydrophobicContact CB-CE3 4.36Å; E178-W261 HydrophobicContact CB-CZ3 4.11Å; E178-W261 HydrophobicContact CG-CD2 4.49Å; E178-W261 HydrophobicContact CG-CE3 3.94Å; E178-W261 HydrophobicContact CG-CH2 4.16Å; E178-W261 HydrophobicContact CG-CZ3 3.79Å; E178-L264 HydrophobicContact CB-CD2 4.42Å
179	Y	94.9	Very high	92.4	Very high	73 Å²	73	48.6 Å²	48.6	29%	0.286	23%	0.233	S	C	.	.	H	α-helix	trans	-58.7	-47	177.2	-175.8	-92.7	0	0	0	111.4	L132 V135 W139 R175 S176 L177 L181 K182 L183	L132-Y179 HydrophobicContact CB-CD1 4.44Å; L132-Y179 HydrophobicContact CD1-CD1 3.54Å; L132-Y179 HydrophobicContact CD1-CE1 4.38Å; L132-Y179 HydrophobicContact CD1-CG 4.26Å; V135-Y179 HydrophobicContact CB-CE1 4.26Å; V135-Y179 HydrophobicContact CG1-CD2 4.37Å; V135-Y179 HydrophobicContact CG1-CE1 4.33Å; V135-Y179 HydrophobicContact CG1-CE2 4.14Å; V135-Y179 HydrophobicContact CG2-CE1 4.12Å; V135-Y179 HydrophobicContact CG2-CE2 4.39Å; W139-Y179 HydrophobicContact CZ2-CD2 4.47Å; R175-Y179 WeakPolarHBondContact O-CB 3.46Å; R175-Y179 PolarHBondContact O-N 3.26Å; S176-Y179 PolarHBondContact O-N 3.31Å; L177-Y179 PolarHBondContact O-N 2.89Å; Y179-L181 VanDerWaalsContact C-N 3.35Å; Y179-L181 PolarHBondContact O-N 3.26Å; Y179-K182 PolarHBondContact O-N 2.92Å; Y179-L183 HydrophobicContact CD1-CD1 4.11Å; Y179-L183 HydrophobicContact CE1-CD1 3.77Å; Y179-L183 HydrophobicContact CE1-CD2 4.49Å; Y179-L183 HydrophobicContact CE1-CG 4.34Å; Y179-L183 WeakPolarHBondContact O-CG 3.43Å; Y179-L183 PolarHBondContact O-N 3.33Å
180	R	94.7	Very high	92.8	Very high	0 Å²	0	47.6 Å²	47.6	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-64.2	-37.8	-178.7	-176.4	56.5	-177.5	73.7	2	113.3	N129 L132 S176 L177 E178 L214 Y242	N129-R180 PolarHBondContact OD1-NE 3.39Å; N129-R180 PolarHBondContact OD1-NH2 3.12Å; L132-R180 HydrophobicContact CD2-CB 4.15Å; L132-R180 HydrophobicContact CD2-CG 4.44Å; S176-R180 PolarHBondContact O-N 3.47Å; L177-R180 PolarHBondContact O-N 3.3Å; E178-R180 VanDerWaalsContact C-N 3.34Å; E178-R180 PolarHBondContact O-N 2.86Å; R180-L214 HydrophobicContact CG-CD1 4.33Å; R180-L214 HydrophobicContact CG-CD2 4.2Å; R180-Y242 HydrophobicContact CG-CE2 3.76Å; R180-Y242 PolarHBondContact NH1-OH 3.49Å
181	L	94.2	Very high	93.1	Very high	0 Å²	0	46.7 Å²	46.7	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-73.4	-35.7	177.6	-73	166.6	0	0	0	111.6	L177 E178 Y179 L183 I184 Y242 T245 E246 M249 W261 L264	L177-L181 WeakPolarHBondContact O-CB 3.46Å; L177-L181 VanDerWaalsContact O-CG 3.31Å; L177-L181 WeakPolarHBondContact O-CG 3.34Å; L177-L181 PolarHBondContact O-N 3.43Å; E178-L181 PolarHBondContact O-N 2.85Å; Y179-L181 VanDerWaalsContact C-N 3.35Å; Y179-L181 PolarHBondContact O-N 3.26Å; L181-L183 PolarHBondContact O-N 3.39Å; L181-I184 HydrophobicContact CD2-CD1 4.36Å; L181-I184 WeakPolarHBondContact O-CB 3.23Å; L181-I184 PolarHBondContact O-N 2.89Å; L181-Y242 HydrophobicContact CD2-CE2 4.12Å; L181-Y242 HydrophobicContact CG-CE2 4.41Å; L181-T245 HydrophobicContact CD1-CG2 3.39Å; L181-E246 HydrophobicContact CD2-CB 4.04Å; L181-M249 HydrophobicContact CB-SD 4.31Å; L181-M249 HydrophobicContact CD2-CE 4.25Å; L181-W261 HydrophobicContact CB-CH2 3.91Å; L181-W261 HydrophobicContact CB-CZ3 3.97Å; L181-W261 HydrophobicContact CD1-CZ3 4.11Å; L181-L264 HydrophobicContact CD1-CD2 4.38Å
182	K	94.1	Very high	93.3	Very high	97 Å²	97	43.5 Å²	43.5	42%	0.422	22%	0.215	S	C	.	.	H	α-helix	trans	-58.1	-32.6	175	-79.5	177.7	-179.5	174.1	0	113.1	E178 Y179 I184 I185 W261	E178-K182 HydrophobicContact CG-CD 4.13Å; E178-K182 WeakPolarHBondContact O-CB 3.4Å; E178-K182 VanDerWaalsContact O-CG 3.3Å; E178-K182 WeakPolarHBondContact O-CG 3.47Å; E178-K182 PolarHBondContact O-N 3.27Å; E178-K182 VanDerWaalsContact OE1-CE 3.23Å; E178-K182 WeakPolarHBondContact OE1-CE 3.38Å; E178-K182 IonicContact OE1-NZ 2.82Å; E178-K182 PolarHBondContact OE1-NZ 3.49Å; Y179-K182 PolarHBondContact O-N 2.92Å; K182-I184 PolarHBondContact O-N 3.37Å; K182-I185 HydrophobicContact CB-CD1 4.15Å; K182-I185 HydrophobicContact CG-CD1 3.91Å; K182-I185 WeakPolarHBondContact O-CB 3.43Å; K182-I185 WeakPolarHBondContact O-CG1 3.12Å; K182-I185 PolarHBondContact O-N 3.47Å; K182-W261 HydrophobicContact CG-CH2 3.8Å; K182-W261 HydrophobicContact CG-CZ2 3.89Å
183	L	93.5	Very high	93.5	Very high	36 Å²	36	46.2 Å²	46.2	19%	0.188	23%	0.228	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65.2	-20.5	176.5	-63.9	167.5	0	0	0	113.5	R128 Y179 L181	R128-L183 HydrophobicContact CB-CD1 4.04Å; R128-L183 HydrophobicContact CG-CB 4.29Å; R128-L183 HydrophobicContact CG-CD1 4.38Å; Y179-L183 HydrophobicContact CD1-CD1 4.11Å; Y179-L183 HydrophobicContact CE1-CD1 3.77Å; Y179-L183 HydrophobicContact CE1-CD2 4.49Å; Y179-L183 HydrophobicContact CE1-CG 4.34Å; Y179-L183 WeakPolarHBondContact O-CG 3.43Å; Y179-L183 PolarHBondContact O-N 3.33Å; L181-L183 PolarHBondContact O-N 3.39Å
184	I	93.6	Very high	93.5	Very high	0 Å²	0	45.9 Å²	45.9	0%	0	23%	0.226	C	C	.	.	T	Hydrogen-bonded Turn	trans	-86.8	-23.7	179.6	-61	168.4	0	0	0	111.5	F124 L181 K182 P186 Y187 L188 W191 E246 M249	F124-I184 HydrophobicContact CE1-CG1 4.23Å; F124-I184 HydrophobicContact CZ-CG1 4.37Å; L181-I184 HydrophobicContact CD2-CD1 4.36Å; L181-I184 WeakPolarHBondContact O-CB 3.23Å; L181-I184 PolarHBondContact O-N 2.89Å; K182-I184 PolarHBondContact O-N 3.37Å; I184-P186 VanDerWaalsContact C-N 3.33Å; I184-P186 VanDerWaalsContact O-N 3.13Å; I184-Y187 CarbonylContact O-C 3.58Å; I184-Y187 WeakPolarHBondContact O-CA 3.48Å; I184-Y187 PolarHBondContact O-N 2.98Å; I184-L188 PolarHBondContact O-N 3.22Å; I184-W191 HydrophobicContact CD1-CZ2 3.73Å; I184-W191 HydrophobicContact CG1-CH2 4.33Å; I184-W191 HydrophobicContact CG1-CZ2 3.96Å; I184-W191 HydrophobicContact CG2-CB 4.38Å; I184-W191 HydrophobicContact CG2-CD2 3.51Å; I184-W191 HydrophobicContact CG2-CE3 4.01Å; I184-W191 HydrophobicContact CG2-CG 3.67Å; I184-W191 HydrophobicContact CG2-CZ2 4.11Å; I184-E246 HydrophobicContact CD1-CG 4.5Å; I184-E246 WeakPolarHBondContact CD1-OE1 3.18Å; I184-M249 HydrophobicContact CB-CE 4.03Å; I184-M249 HydrophobicContact CG2-CE 4Å
185	I	92.5	Very high	93.6	Very high	70 Å²	70	46 Å²	46	36%	0.359	23%	0.229	S	C	.	.	G	3₁₀ helix	trans	-48.3	-43.8	-173.7	-64	174.9	0	0	0	113.7	K182 Y187 L188 L257 W261	K182-I185 HydrophobicContact CB-CD1 4.15Å; K182-I185 HydrophobicContact CG-CD1 3.91Å; K182-I185 WeakPolarHBondContact O-CB 3.43Å; K182-I185 WeakPolarHBondContact O-CG1 3.12Å; K182-I185 PolarHBondContact O-N 3.47Å; I185-Y187 PolarHBondContact O-N 3.25Å; I185-Y187 VanDerWaalsContact O-N 3.12Å; I185-L188 WeakPolarHBondContact O-CB 3.31Å; I185-L188 PolarHBondContact O-N 3.38Å; I185-L257 HydrophobicContact CD1-CD1 4.02Å; I185-L257 HydrophobicContact CG1-CD1 3.92Å; I185-W261 HydrophobicContact CD1-CZ2 4.29Å
186	P	92	Very high	93.6	Very high	87 Å²	87	41.7 Å²	41.7	57%	0.565	22%	0.224	S	C	*	.	G	3₁₀ helix	trans	-61.9	-22.7	179.2	-22.8	34.7	0	0	0	114.3	I184	I184-P186 VanDerWaalsContact C-N 3.33Å; I184-P186 VanDerWaalsContact O-N 3.13Å
187	Y	93.1	Very high	93.5	Very high	31 Å²	31	43.9 Å²	43.9	12%	0.122	24%	0.235	C	C	.	.	G	3₁₀ helix	trans	-107.9	6.8	-175.1	-53.8	-73.3	0	0	0	113.1	L82 V85 P86 W90 F124 I184 I185 N189 V190 W191	L82-Y187 VanDerWaalsContact O-CE1 3.31Å; L82-Y187 WeakPolarHBondContact O-CE1 3.49Å; L82-Y187 PolarHBondContact O-OH 3.02Å; V85-Y187 HydrophobicContact CB-CD1 4.24Å; V85-Y187 HydrophobicContact CB-CE1 4.18Å; V85-Y187 HydrophobicContact CG1-CD1 3.88Å; V85-Y187 HydrophobicContact CG1-CE1 4.3Å; P86-Y187 HydrophobicContact CG-CD1 4.18Å; P86-Y187 HydrophobicContact CG-CE1 4.11Å; W90-Y187 HydrophobicContact CZ2-CD1 4.4Å; W90-Y187 HydrophobicContact CZ2-CG 4.27Å; F124-Y187 HydrophobicContact CD2-CE2 4.34Å; F124-Y187 AromaticContact CE2-CD2 3.7Å; F124-Y187 HydrophobicContact CE2-CD2 3.7Å; F124-Y187 AromaticContact CE2-CE2 3.54Å; F124-Y187 HydrophobicContact CE2-CE2 3.54Å; F124-Y187 AromaticContact CZ-CD2 3.99Å; F124-Y187 HydrophobicContact CZ-CD2 3.99Å; F124-Y187 HydrophobicContact CZ-CE2 4.25Å; I184-Y187 CarbonylContact O-C 3.58Å; I184-Y187 WeakPolarHBondContact O-CA 3.48Å; I184-Y187 PolarHBondContact O-N 2.98Å; I185-Y187 PolarHBondContact O-N 3.25Å; I185-Y187 VanDerWaalsContact O-N 3.12Å; Y187-N189 PolarHBondContact O-N 3.4Å; Y187-N189 VanDerWaalsContact O-N 3.11Å; Y187-V190 CarbonylContact O-C 3.56Å; Y187-V190 VanDerWaalsContact O-CG2 3.3Å; Y187-V190 WeakPolarHBondContact O-CG2 3.31Å; Y187-V190 PolarHBondContact O-N 2.61Å; Y187-W191 WeakPolarHBondContact O-CB 3.49Å; Y187-W191 PolarHBondContact O-N 3.04Å
188	L	91.2	Very high	93.4	Very high	34 Å²	34	44.4 Å²	44.4	18%	0.178	24%	0.238	C	C	.	.	T	Hydrogen-bonded Turn	trans	-53	-39.9	-171.3	-164.5	77.8	0	0	0	113	I184 I185 V190 W191 P192 M249 L250 L257	I184-L188 PolarHBondContact O-N 3.22Å; I185-L188 WeakPolarHBondContact O-CB 3.31Å; I185-L188 PolarHBondContact O-N 3.38Å; L188-V190 VanDerWaalsContact C-N 3.29Å; L188-V190 PolarHBondContact O-N 2.69Å; L188-W191 PolarHBondContact O-N 3.45Å; L188-P192 WeakPolarHBondContact O-CD 3.38Å; L188-M249 HydrophobicContact CD1-CE 3.73Å; L188-M249 HydrophobicContact CD1-CG 3.95Å; L188-M249 HydrophobicContact CD1-SD 4.48Å; L188-L250 HydrophobicContact CD1-CD2 4.19Å; L188-L257 HydrophobicContact CD2-CD2 4.42Å
189	N	91.4	Very high	93.3	Very high	155 Å²	155	46.2 Å²	46.2	83%	0.829	26%	0.255	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.1	-33.2	-178.7	-63.7	-21.1	0	0	0	113.5	Y187	Y187-N189 PolarHBondContact O-N 3.4Å; Y187-N189 VanDerWaalsContact O-N 3.11Å
190	V	93.9	Very high	93.3	Very high	25 Å²	25	46.8 Å²	46.8	15%	0.152	26%	0.262	C	S	.	.	T	Hydrogen-bonded Turn	trans	-105.6	-2.4	-178.7	-65.8	0	0	0	0	112.2	V85 W90 Y187 L188 P192 Q193	V85-V190 HydrophobicContact CG1-CG2 3.9Å; W90-V190 VanDerWaalsContact CD1-O 3.22Å; W90-V190 PolarHBondContact NE1-O 3.41Å; Y187-V190 CarbonylContact O-C 3.56Å; Y187-V190 VanDerWaalsContact O-CG2 3.3Å; Y187-V190 WeakPolarHBondContact O-CG2 3.31Å; Y187-V190 PolarHBondContact O-N 2.61Å; L188-V190 VanDerWaalsContact C-N 3.29Å; L188-V190 PolarHBondContact O-N 2.69Å; V190-P192 VanDerWaalsContact C-CD 3.5Å; V190-Q193 VanDerWaalsContact O-CB 3.3Å; V190-Q193 WeakPolarHBondContact O-CB 3.46Å; V190-Q193 PolarHBondContact O-N 3.48Å
191	W	94.1	Very high	93.2	Very high	0 Å²	0	51.9 Å²	51.9	0%	0	30%	0.295	C	S	.	.	H	α-helix	trans	-63	-36.2	-178.5	-161.5	-118.4	0	0	0	114.8	W90 F124 Y125 I184 Y187 L188 Q193 A194 L195 E246 L250	W90-W191 HydrophobicContact CH2-CZ3 4.18Å; W90-W191 AromaticContact CZ2-CE3 3.86Å; W90-W191 HydrophobicContact CZ2-CE3 3.86Å; W90-W191 AromaticContact CZ2-CZ3 3.6Å; W90-W191 HydrophobicContact CZ2-CZ3 3.6Å; F124-W191 AromaticContact CD1-CH2 3.6Å; F124-W191 HydrophobicContact CD1-CH2 3.6Å; F124-W191 AromaticContact CD1-CZ3 3.81Å; F124-W191 HydrophobicContact CD1-CZ3 3.81Å; F124-W191 AromaticContact CE1-CH2 3.36Å; F124-W191 HydrophobicContact CE1-CH2 3.36Å; F124-W191 HydrophobicContact CE1-CZ2 4.36Å; F124-W191 AromaticContact CE1-CZ3 3.61Å; F124-W191 HydrophobicContact CE1-CZ3 3.61Å; F124-W191 HydrophobicContact CZ-CH2 4.4Å; F124-W191 HydrophobicContact CZ-CZ3 4.33Å; Y125-W191 HydrophobicContact CD2-CH2 4.1Å; Y125-W191 AromaticContact CE2-CH2 3.38Å; Y125-W191 HydrophobicContact CE2-CH2 3.38Å; Y125-W191 AromaticContact CE2-CZ2 3.59Å; Y125-W191 HydrophobicContact CE2-CZ2 3.59Å; Y125-W191 AromaticContact CZ-CH2 3.85Å; Y125-W191 AromaticContact CZ-CZ2 3.56Å; Y125-W191 WeakPolarHBondContact OH-CZ2 3.5Å; I184-W191 HydrophobicContact CD1-CZ2 3.73Å; I184-W191 HydrophobicContact CG1-CH2 4.33Å; I184-W191 HydrophobicContact CG1-CZ2 3.96Å; I184-W191 HydrophobicContact CG2-CB 4.38Å; I184-W191 HydrophobicContact CG2-CD2 3.51Å; I184-W191 HydrophobicContact CG2-CE3 4.01Å; I184-W191 HydrophobicContact CG2-CG 3.67Å; I184-W191 HydrophobicContact CG2-CZ2 4.11Å; Y187-W191 WeakPolarHBondContact O-CB 3.49Å; Y187-W191 PolarHBondContact O-N 3.04Å; L188-W191 PolarHBondContact O-N 3.45Å; W191-Q193 PolarHBondContact O-N 3.05Å; W191-A194 HydrophobicContact CD2-CB 4.36Å; W191-A194 HydrophobicContact CE3-CB 3.93Å; W191-A194 HydrophobicContact CZ3-CB 4.12Å; W191-A194 WeakPolarHBondContact O-CB 3.29Å; W191-A194 PolarHBondContact O-N 3.41Å; W191-L195 PolarHBondContact O-N 2.87Å; W191-E246 VanDerWaalsContact CZ2-OE1 3.31Å; W191-E246 WeakPolarHBondContact CZ2-OE1 3.24Å; W191-E246 PolarHBondContact NE1-OE1 2.95Å; W191-L250 HydrophobicContact CB-CD2 3.92Å; W191-L250 HydrophobicContact CG-CD2 4.3Å
192	P	94.2	Very high	93.1	Very high	70 Å²	70	59.5 Å²	59.5	46%	0.455	33%	0.328	S	S	.	.	H	α-helix	trans	-57.2	-33.7	173.9	-26.2	34.9	0	0	0	113.2	L188 V190 G196 L250	L188-P192 WeakPolarHBondContact O-CD 3.38Å; V190-P192 VanDerWaalsContact C-CD 3.5Å; P192-G196 PolarHBondContact O-N 2.8Å; P192-L250 HydrophobicContact CG-CD1 4.32Å; P192-L250 HydrophobicContact CG-CD2 3.89Å
193	Q	93.8	Very high	93	Very high	87 Å²	87	55.4 Å²	55.4	41%	0.407	31%	0.311	S	S	.	.	H	α-helix	trans	-65	-43.8	174.8	-173	-172.3	17.6	0	0	111	V190 W191 G196 L197	V190-Q193 VanDerWaalsContact O-CB 3.3Å; V190-Q193 WeakPolarHBondContact O-CB 3.46Å; V190-Q193 PolarHBondContact O-N 3.48Å; W191-Q193 PolarHBondContact O-N 3.05Å; Q193-G196 PolarHBondContact O-N 3.29Å; Q193-L197 WeakPolarHBondContact O-CG 3.26Å; Q193-L197 PolarHBondContact O-N 3.32Å
194	A	93.9	Very high	92.9	Very high	0 Å²	0	56.9 Å²	56.9	0%	0	32%	0.319	C	S	.	.	H	α-helix	trans	-62.3	-46.3	177	0	0	0	0	0	112.1	W90 V121 W191 G196 L197 L198	W90-A194 HydrophobicContact CD2-CB 4.17Å; W90-A194 HydrophobicContact CG-CB 4.01Å; V121-A194 HydrophobicContact CG1-CB 4.12Å; V121-A194 HydrophobicContact CG2-CB 3.71Å; W191-A194 HydrophobicContact CD2-CB 4.36Å; W191-A194 HydrophobicContact CE3-CB 3.93Å; W191-A194 HydrophobicContact CZ3-CB 4.12Å; W191-A194 WeakPolarHBondContact O-CB 3.29Å; W191-A194 PolarHBondContact O-N 3.41Å; A194-G196 VanDerWaalsContact C-N 3.28Å; A194-G196 PolarHBondContact O-N 3.06Å; A194-L197 WeakPolarHBondContact O-CB 3.42Å; A194-L197 PolarHBondContact O-N 2.99Å; A194-L197 VanDerWaalsContact O-N 3.14Å; A194-L198 WeakPolarHBondContact O-CG 3.31Å; A194-L198 PolarHBondContact O-N 2.71Å
195	L	93.7	Very high	92.8	Very high	35 Å²	35	61.2 Å²	61.2	18%	0.183	35%	0.347	C	S	.	.	H	α-helix	trans	-62.2	-37.6	176.2	-68.9	176	0	0	0	111.8	W191 L197 L198 S199 L247 L250	W191-L195 PolarHBondContact O-N 2.87Å; L195-L197 PolarHBondContact O-N 3.43Å; L195-L198 HydrophobicContact CD2-CD1 4.38Å; L195-L198 PolarHBondContact O-N 3.01Å; L195-S199 WeakPolarHBondContact O-CB 3.27Å; L195-S199 PolarHBondContact O-N 2.9Å; L195-L247 HydrophobicContact CD1-CD2 4.19Å; L195-L250 HydrophobicContact CD1-CD1 3.65Å
196	G	93.9	Very high	92.7	Very high	35 Å²	35	62.1 Å²	62.1	36%	0.361	35%	0.352	S	S	.	.	H	α-helix	trans	-57.7	-47.2	171.8	0	0	0	0	0	112	P192 Q193 A194 L198 S199	P192-G196 PolarHBondContact O-N 2.8Å; Q193-G196 PolarHBondContact O-N 3.29Å; A194-G196 VanDerWaalsContact C-N 3.28Å; A194-G196 PolarHBondContact O-N 3.06Å; G196-L198 VanDerWaalsContact C-N 3.35Å; G196-L198 PolarHBondContact O-N 3.02Å; G196-S199 PolarHBondContact O-N 2.97Å; G196-S199 PolarHBondContact O-OG 3.35Å
197	L	93	Very high	92.7	Very high	46 Å²	46	59.3 Å²	59.3	24%	0.241	33%	0.334	C	S	.	.	H	α-helix	trans	-63.1	-38.2	176.7	-66.9	173.9	0	0	0	112.5	W90 I118 Q193 A194 L195 S199 L200 N203	W90-L197 HydrophobicContact CB-CD1 4.05Å; I118-L197 HydrophobicContact CD1-CB 4.26Å; Q193-L197 WeakPolarHBondContact O-CG 3.26Å; Q193-L197 PolarHBondContact O-N 3.32Å; A194-L197 WeakPolarHBondContact O-CB 3.42Å; A194-L197 PolarHBondContact O-N 2.99Å; A194-L197 VanDerWaalsContact O-N 3.14Å; L195-L197 PolarHBondContact O-N 3.43Å; L197-S199 VanDerWaalsContact C-N 3.33Å; L197-L200 HydrophobicContact CD2-CD1 4.28Å; L197-L200 WeakPolarHBondContact O-CB 3.47Å; L197-L200 PolarHBondContact O-N 3.4Å; L197-N203 PolarHBondContact O-ND2 3.39Å
198	L	92	Very high	92.7	Very high	13 Å²	13	62.8 Å²	62.8	7%	0.068	35%	0.354	C	S	.	.	H	α-helix	trans	-70.6	-28.2	177.3	-69.3	166.2	0	0	0	113.1	I118 V121 L122 Y125 A194 L195 G196 L200	I118-L198 HydrophobicContact CD1-CD2 3.8Å; I118-L198 HydrophobicContact CD1-CG 4.34Å; V121-L198 HydrophobicContact CG1-CD1 3.75Å; V121-L198 HydrophobicContact CG1-CD2 3.98Å; V121-L198 HydrophobicContact CG1-CG 3.9Å; L122-L198 HydrophobicContact CD2-CD2 4.33Å; Y125-L198 HydrophobicContact CD2-CD1 4.28Å; Y125-L198 HydrophobicContact CE2-CD1 3.45Å; Y125-L198 VanDerWaalsContact CE2-CD1 3.45Å; A194-L198 WeakPolarHBondContact O-CG 3.31Å; A194-L198 PolarHBondContact O-N 2.71Å; L195-L198 HydrophobicContact CD2-CD1 4.38Å; L195-L198 PolarHBondContact O-N 3.01Å; G196-L198 VanDerWaalsContact C-N 3.35Å; G196-L198 PolarHBondContact O-N 3.02Å; L198-L200 VanDerWaalsContact C-N 3.25Å; L198-L200 PolarHBondContact O-N 3.2Å
199	S	92.4	Very high	92.8	Very high	76 Å²	76	62.5 Å²	62.5	53%	0.531	36%	0.359	S	S	.	.	T	Hydrogen-bonded Turn	trans	-75.2	-11.6	178.5	78	0	0	0	0	113.9	L195 G196 L197 I204	L195-S199 WeakPolarHBondContact O-CB 3.27Å; L195-S199 PolarHBondContact O-N 2.9Å; G196-S199 PolarHBondContact O-N 2.97Å; G196-S199 PolarHBondContact O-OG 3.35Å; L197-S199 VanDerWaalsContact C-N 3.33Å; S199-I204 WeakPolarHBondContact O-CD1 3.49Å
200	L	93.4	Very high	92.8	Very high	85 Å²	85	55.8 Å²	55.8	45%	0.445	32%	0.323	S	S	.	.	S	Bend	trans	-64.1	133.2	178.1	-68.6	172.1	0	0	0	110.3	L197 L198 K202 N203 I204	L197-L200 HydrophobicContact CD2-CD1 4.28Å; L197-L200 WeakPolarHBondContact O-CB 3.47Å; L197-L200 PolarHBondContact O-N 3.4Å; L198-L200 VanDerWaalsContact C-N 3.25Å; L198-L200 PolarHBondContact O-N 3.2Å; L200-K202 PolarHBondContact O-N 2.87Å; L200-N203 PolarHBondContact O-N 3.49Å; L200-I204 WeakPolarHBondContact O-CG1 3.39Å; L200-I204 PolarHBondContact O-N 2.81Å; L200-I204 VanDerWaalsContact O-N 3.14Å
201	P	92.6	Very high	92.8	Very high	107 Å²	107	56 Å²	56	70%	0.695	32%	0.323	S	S	*	.	T	Hydrogen-bonded Turn	trans	-51.9	-30.5	-174.9	-30.5	35.2	0	0	0	115.5	N203	P201-N203 VanDerWaalsContact C-N 3.31Å; P201-N203 PolarHBondContact O-N 3.22Å
202	K	92.3	Very high	92.7	Very high	160 Å²	160	58 Å²	58	70%	0.696	34%	0.34	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.1	-34.1	175.5	-170.5	-172.6	-179.8	-162.7	0	112.9	L200	L200-K202 PolarHBondContact O-N 2.87Å
203	N	91.8	Very high	92.6	Very high	12 Å²	12	60 Å²	60	6%	0.064	34%	0.343	C	S	.	.	T	Hydrogen-bonded Turn	trans	-99.6	-18.1	-172.5	-59.1	-25	0	0	0	112.7	I118 L197 L200 P201 L206 S207	I118-N203 HydrophobicContact CD1-CB 4.21Å; I118-N203 HydrophobicContact CG1-CB 4.49Å; L197-N203 PolarHBondContact O-ND2 3.39Å; L200-N203 PolarHBondContact O-N 3.49Å; P201-N203 VanDerWaalsContact C-N 3.31Å; P201-N203 PolarHBondContact O-N 3.22Å; N203-L206 PolarHBondContact O-N 2.93Å; N203-L206 VanDerWaalsContact O-N 3.1Å; N203-S207 PolarHBondContact O-N 2.95Å; N203-S207 PolarHBondContact O-OG 2.87Å
204	I	91.7	Very high	92.6	Very high	67 Å²	67	56.1 Å²	56.1	34%	0.344	33%	0.325	S	S	.	.	H	α-helix	trans	-51.2	-47.4	-178.8	-69.2	176.8	0	0	0	113.6	S199 L200 L206 S207 I208	S199-I204 WeakPolarHBondContact O-CD1 3.49Å; L200-I204 WeakPolarHBondContact O-CG1 3.39Å; L200-I204 PolarHBondContact O-N 2.81Å; L200-I204 VanDerWaalsContact O-N 3.14Å; I204-L206 PolarHBondContact O-N 3.47Å; I204-S207 WeakPolarHBondContact CA-OG 3.38Å; I204-S207 PolarHBondContact O-N 3.34Å; I204-S207 PolarHBondContact O-OG 2.79Å; I204-I208 HydrophobicContact CG2-CD1 3.5Å; I204-I208 VanDerWaalsContact CG2-CD1 3.5Å; I204-I208 HydrophobicContact CG2-CG1 4.17Å; I204-I208 WeakPolarHBondContact O-CB 3.42Å; I204-I208 VanDerWaalsContact O-CG1 3.31Å; I204-I208 WeakPolarHBondContact O-CG1 3.4Å; I204-I208 PolarHBondContact O-N 3.44Å
205	P	92.7	Very high	92.5	Very high	91 Å²	91	56.2 Å²	56.2	59%	0.591	33%	0.326	S	S	*	.	H	α-helix	trans	-61.9	-36.4	-178.6	-23.7	34.9	0	0	0	112.4	G209	P205-G209 PolarHBondContact O-N 3.46Å; P205-G209 VanDerWaalsContact O-N 3.08Å
206	L	90.7	Very high	92.4	Very high	88 Å²	88	56 Å²	56	46%	0.461	33%	0.325	S	S	.	.	H	α-helix	trans	-74	-44.3	179.4	-173.7	60	0	0	0	111.2	L122 N203 I204 I208 G209 M210	L122-L206 HydrophobicContact CD1-CD2 3.39Å; L122-L206 HydrophobicContact CD2-CD2 3.54Å; L122-L206 HydrophobicContact CD2-CG 3.78Å; L122-L206 HydrophobicContact CG-CD2 4.08Å; N203-L206 PolarHBondContact O-N 2.93Å; N203-L206 VanDerWaalsContact O-N 3.1Å; I204-L206 PolarHBondContact O-N 3.47Å; L206-I208 PolarHBondContact O-N 3.37Å; L206-G209 PolarHBondContact O-N 2.84Å; L206-G209 VanDerWaalsContact O-N 3.15Å; L206-M210 WeakPolarHBondContact O-CG 3.26Å; L206-M210 PolarHBondContact O-N 2.82Å
207	S	90.6	Very high	92.3	Very high	28 Å²	28	57.1 Å²	57.1	20%	0.196	32%	0.321	C	S	.	.	H	α-helix	trans	-63.8	-39.9	178.3	65	0	0	0	0	112.4	N203 I204 M210 L211	N203-S207 PolarHBondContact O-N 2.95Å; N203-S207 PolarHBondContact O-OG 2.87Å; I204-S207 WeakPolarHBondContact CA-OG 3.38Å; I204-S207 PolarHBondContact O-N 3.34Å; I204-S207 PolarHBondContact O-OG 2.79Å; S207-M210 PolarHBondContact O-N 3.43Å; S207-L211 WeakPolarHBondContact O-CB 3.31Å; S207-L211 PolarHBondContact O-N 3.46Å
208	I	93.1	Very high	92.2	Very high	104 Å²	104	55 Å²	55	53%	0.533	31%	0.309	S	S	.	.	H	α-helix	trans	-64.5	-41	172.9	-68	173.7	0	0	0	110.8	I204 L206 L211 A212	I204-I208 HydrophobicContact CG2-CD1 3.5Å; I204-I208 VanDerWaalsContact CG2-CD1 3.5Å; I204-I208 HydrophobicContact CG2-CG1 4.17Å; I204-I208 WeakPolarHBondContact O-CB 3.42Å; I204-I208 VanDerWaalsContact O-CG1 3.31Å; I204-I208 WeakPolarHBondContact O-CG1 3.4Å; I204-I208 PolarHBondContact O-N 3.44Å; L206-I208 PolarHBondContact O-N 3.37Å; I208-L211 PolarHBondContact O-N 2.87Å; I208-A212 WeakPolarHBondContact O-CB 3.36Å; I208-A212 PolarHBondContact O-N 3.3Å
209	G	93.3	Very high	92.1	Very high	28 Å²	28	55.3 Å²	55.3	29%	0.289	31%	0.31	S	S	.	.	H	α-helix	trans	-57.7	-48.2	175.6	0	0	0	0	0	112.2	P205 L206 L211 A212 E213	P205-G209 PolarHBondContact O-N 3.46Å; P205-G209 VanDerWaalsContact O-N 3.08Å; L206-G209 PolarHBondContact O-N 2.84Å; L206-G209 VanDerWaalsContact O-N 3.15Å; G209-L211 VanDerWaalsContact C-N 3.34Å; G209-L211 PolarHBondContact O-N 3.46Å; G209-A212 WeakPolarHBondContact O-CB 3.36Å; G209-A212 PolarHBondContact O-N 3.27Å; G209-E213 WeakPolarHBondContact O-CG 3.35Å; G209-E213 PolarHBondContact O-N 3.48Å
210	M	92.3	Very high	91.8	Very high	15 Å²	15	54.4 Å²	54.4	7%	0.074	31%	0.306	C	S	.	.	H	α-helix	trans	-65	-35.6	178	-63.1	-176.2	85.8	0	0	113.3	L122 A126 N129 L206 S207 L214	L122-M210 HydrophobicContact CD2-SD 3.47Å; L122-M210 WeakPolarHBondContact CD2-SD 3.41Å; L122-M210 VanDerWaalsContact O-CE 3.27Å; L122-M210 WeakPolarHBondContact O-CE 3.32Å; A126-M210 HydrophobicContact CB-CE 3.81Å; N129-M210 PolarHBondContact ND2-O 3.15Å; L206-M210 WeakPolarHBondContact O-CG 3.26Å; L206-M210 PolarHBondContact O-N 2.82Å; S207-M210 PolarHBondContact O-N 3.43Å; M210-L214 WeakPolarHBondContact O-CB 3.34Å; M210-L214 PolarHBondContact O-N 3.37Å
211	L	93.2	Very high	91.5	Very high	29 Å²	29	50.9 Å²	50.9	15%	0.152	29%	0.288	C	S	.	.	H	α-helix	trans	-69.3	-40.3	174.1	180	62.2	0	0	0	111.3	S207 I208 G209 L214 V215 A239 Y242 N243	S207-L211 WeakPolarHBondContact O-CB 3.31Å; S207-L211 PolarHBondContact O-N 3.46Å; I208-L211 PolarHBondContact O-N 2.87Å; G209-L211 VanDerWaalsContact C-N 3.34Å; G209-L211 PolarHBondContact O-N 3.46Å; L211-L214 HydrophobicContact CD1-CD2 4.35Å; L211-L214 PolarHBondContact O-N 3.21Å; L211-V215 HydrophobicContact CD1-CG2 4.3Å; L211-V215 VanDerWaalsContact O-CG2 3.3Å; L211-V215 WeakPolarHBondContact O-CG2 3.34Å; L211-V215 PolarHBondContact O-N 2.91Å; L211-A239 HydrophobicContact CD2-CB 4.18Å; L211-A239 HydrophobicContact CG-CB 4.38Å; L211-Y242 HydrophobicContact CD1-CD1 3.55Å; L211-Y242 HydrophobicContact CD1-CE1 4.01Å; L211-Y242 HydrophobicContact CD1-CG 4.33Å; L211-N243 VanDerWaalsContact CD2-ND2 3.27Å; L211-N243 WeakPolarHBondContact CD2-ND2 3.21Å
212	A	92.5	Very high	91.1	Very high	43 Å²	43	46.1 Å²	46.1	36%	0.355	26%	0.258	S	S	.	.	H	α-helix	trans	-62.2	-46.9	175.9	0	0	0	0	0	110.8	I208 G209 L214 V215 D216	I208-A212 WeakPolarHBondContact O-CB 3.36Å; I208-A212 PolarHBondContact O-N 3.3Å; G209-A212 WeakPolarHBondContact O-CB 3.36Å; G209-A212 PolarHBondContact O-N 3.27Å; A212-L214 PolarHBondContact O-N 2.9Å; A212-V215 PolarHBondContact O-N 2.92Å; A212-D216 VanDerWaalsContact O-CB 3.27Å; A212-D216 WeakPolarHBondContact O-CB 3.34Å; A212-D216 PolarHBondContact O-N 2.63Å
213	E	92	Very high	90.5	Very high	111 Å²	111	39.6 Å²	39.6	52%	0.519	24%	0.236	S	C	.	.	H	α-helix	trans	-57.4	-44.9	174.7	-74	172.5	-171.5	0	0	112.3	G209 V215 D216 E217	G209-E213 WeakPolarHBondContact O-CG 3.35Å; G209-E213 PolarHBondContact O-N 3.48Å; E213-V215 PolarHBondContact O-N 2.89Å; E213-D216 PolarHBondContact O-N 3.49Å; E213-E217 VanDerWaalsContact O-CB 3.31Å; E213-E217 WeakPolarHBondContact O-CB 3.38Å; E213-E217 PolarHBondContact O-N 2.86Å
214	L	93.5	Very high	89.7	Confident	5 Å²	5	41 Å²	41	3%	0.026	24%	0.243	C	C	.	.	H	α-helix	trans	-58.5	-48.7	176.2	172.1	63.8	0	0	0	111.8	L132 R180 M210 L211 A212 E217 I218 Y242	L132-L214 HydrophobicContact CD2-CD1 3.35Å; R180-L214 HydrophobicContact CG-CD1 4.33Å; R180-L214 HydrophobicContact CG-CD2 4.2Å; M210-L214 WeakPolarHBondContact O-CB 3.34Å; M210-L214 PolarHBondContact O-N 3.37Å; L211-L214 HydrophobicContact CD1-CD2 4.35Å; L211-L214 PolarHBondContact O-N 3.21Å; A212-L214 PolarHBondContact O-N 2.9Å; L214-E217 PolarHBondContact O-N 2.99Å; L214-I218 HydrophobicContact CD1-CD1 4.06Å; L214-I218 HydrophobicContact CD1-CG1 4.5Å; L214-I218 HydrophobicContact CG-CD1 4.18Å; L214-I218 VanDerWaalsContact O-CG1 3.31Å; L214-I218 WeakPolarHBondContact O-CG1 3.47Å; L214-I218 PolarHBondContact O-N 3.31Å; L214-Y242 HydrophobicContact CD2-CD2 4.29Å; L214-Y242 HydrophobicContact CD2-CE1 4.44Å; L214-Y242 HydrophobicContact CD2-CE2 4.07Å
215	V	93	Very high	88.4	Confident	3 Å²	3	48.2 Å²	48.2	2%	0.018	27%	0.266	C	S	.	.	H	α-helix	trans	-69.4	-38.7	-177.8	173.5	0	0	0	0	111	L211 A212 E213 I218 W219 R235 V238 A239	L211-V215 HydrophobicContact CD1-CG2 4.3Å; L211-V215 VanDerWaalsContact O-CG2 3.3Å; L211-V215 WeakPolarHBondContact O-CG2 3.34Å; L211-V215 PolarHBondContact O-N 2.91Å; A212-V215 PolarHBondContact O-N 2.92Å; E213-V215 PolarHBondContact O-N 2.89Å; V215-I218 PolarHBondContact O-N 3.01Å; V215-W219 VanDerWaalsContact O-CD1 3.24Å; V215-W219 PolarHBondContact O-N 3.05Å; V215-R235 HydrophobicContact CG1-CB 4.08Å; V215-R235 HydrophobicContact CG1-CG 4.02Å; V215-V238 HydrophobicContact CG1-CB 3.98Å; V215-V238 HydrophobicContact CG1-CG1 4.16Å; V215-V238 HydrophobicContact CG2-CG1 4.18Å; V215-A239 HydrophobicContact CG2-CB 4.04Å
216	D	90.9	Very high	87.4	Confident	31 Å²	31	45.3 Å²	45.3	17%	0.166	25%	0.248	C	C	.	.	H	α-helix	trans	-59.4	-46.7	173.3	-86.6	-40	0	0	0	111.4	A212 E213 W219 A220 R235	A212-D216 VanDerWaalsContact O-CB 3.27Å; A212-D216 WeakPolarHBondContact O-CB 3.34Å; A212-D216 PolarHBondContact O-N 2.63Å; E213-D216 PolarHBondContact O-N 3.49Å; D216-W219 PolarHBondContact O-N 2.97Å; D216-A220 VanDerWaalsContact O-CB 3.29Å; D216-A220 WeakPolarHBondContact O-CB 3.49Å; D216-A220 PolarHBondContact O-N 3.36Å; D216-R235 IonicContact OD1-CZ 3.84Å; D216-R235 IonicContact OD1-NE 2.75Å; D216-R235 PolarHBondContact OD1-NE 3.49Å; D216-R235 IonicContact OD1-NH2 2.73Å; D216-R235 PolarHBondContact OD1-NH2 3.27Å
217	E	91	Very high	86.2	Confident	58 Å²	58	47 Å²	47	27%	0.271	26%	0.262	S	S	.	.	H	α-helix	trans	-62.2	-46.9	178.7	-172.5	57.2	-143.9	0	0	110.8	A133 M136 E213 L214 W219 A220 Q221	A133-E217 HydrophobicContact CB-CG 3.89Å; M136-E217 HydrophobicContact CE-CG 3.82Å; E213-E217 VanDerWaalsContact O-CB 3.31Å; E213-E217 WeakPolarHBondContact O-CB 3.38Å; E213-E217 PolarHBondContact O-N 2.86Å; L214-E217 PolarHBondContact O-N 2.99Å; E217-W219 VanDerWaalsContact C-N 3.33Å; E217-W219 PolarHBondContact O-N 2.96Å; E217-A220 PolarHBondContact O-N 3.46Å; E217-Q221 VanDerWaalsContact O-CG 3.23Å; E217-Q221 WeakPolarHBondContact O-CG 3.42Å; E217-Q221 PolarHBondContact O-N 2.98Å; E217-Q221 PolarHBondContact OE1-NE2 3.23Å
218	I	91.6	Very high	85.4	Confident	0 Å²	0	51.1 Å²	51.1	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-57.4	-46	176.2	-67.2	166.9	0	0	0	111	L132 M136 F172 L173 L177 L214 V215 Q221 A222	L132-I218 HydrophobicContact CD2-CD1 4.25Å; L132-I218 HydrophobicContact CD2-CG1 4.14Å; M136-I218 HydrophobicContact CE-CG1 4.23Å; M136-I218 HydrophobicContact SD-CG1 4.21Å; F172-I218 HydrophobicContact CE1-CG2 4.2Å; F172-I218 WeakPolarHBondContact CE1-O 3.39Å; L173-I218 HydrophobicContact CD2-CG2 3.63Å; L177-I218 HydrophobicContact CD2-CD1 4.03Å; L214-I218 HydrophobicContact CD1-CD1 4.06Å; L214-I218 HydrophobicContact CD1-CG1 4.5Å; L214-I218 HydrophobicContact CG-CD1 4.18Å; L214-I218 VanDerWaalsContact O-CG1 3.31Å; L214-I218 WeakPolarHBondContact O-CG1 3.47Å; L214-I218 PolarHBondContact O-N 3.31Å; V215-I218 PolarHBondContact O-N 3.01Å; I218-Q221 PolarHBondContact O-N 2.92Å; I218-A222 WeakPolarHBondContact O-CB 3.31Å; I218-A222 PolarHBondContact O-N 3.02Å
219	W	88.9	Confident	84.6	Confident	21 Å²	21	53.2 Å²	53.2	8%	0.08	29%	0.294	C	S	.	.	H	α-helix	trans	-70.4	-32.7	179	-81.6	114.2	0	0	0	113.4	I169 L173 V215 D216 E217 A222 G223 D224 K234 V238	I169-W219 HydrophobicContact CG2-CH2 4.4Å; I169-W219 HydrophobicContact CG2-CZ3 4.17Å; L173-W219 HydrophobicContact CD1-CH2 4.18Å; L173-W219 HydrophobicContact CD1-CZ2 4.34Å; V215-W219 VanDerWaalsContact O-CD1 3.24Å; V215-W219 PolarHBondContact O-N 3.05Å; D216-W219 PolarHBondContact O-N 2.97Å; E217-W219 VanDerWaalsContact C-N 3.33Å; E217-W219 PolarHBondContact O-N 2.96Å; W219-A222 HydrophobicContact CE3-CB 4.2Å; W219-A222 PolarHBondContact O-N 3.28Å; W219-G223 PolarHBondContact O-N 2.93Å; W219-G223 VanDerWaalsContact O-N 3.15Å; W219-D224 HydrophobicContact CB-CB 4.42Å; W219-D224 HydrophobicContact CD2-CB 4.41Å; W219-D224 HydrophobicContact CE3-CB 3.65Å; W219-D224 HydrophobicContact CZ3-CB 4.33Å; W219-D224 PolarHBondContact O-N 3.49Å; W219-D224 VanDerWaalsContact O-N 3.1Å; W219-K234 HydrophobicContact CD2-CB 4.47Å; W219-K234 HydrophobicContact CH2-CB 4.28Å; W219-K234 HydrophobicContact CH2-CD 4.03Å; W219-K234 HydrophobicContact CH2-CG 3.99Å; W219-K234 HydrophobicContact CZ2-CB 3.62Å; W219-K234 HydrophobicContact CZ2-CD 4.2Å; W219-K234 HydrophobicContact CZ2-CG 3.82Å; W219-K234 HydrophobicContact CZ3-CD 4.21Å; W219-K234 PolarHBondContact NE1-O 3.1Å; W219-V238 HydrophobicContact CZ2-CG2 3.63Å; W219-V238 VanDerWaalsContact NE1-CG2 3.34Å
220	A	87.5	Confident	84	Confident	56 Å²	56	54 Å²	54	46%	0.463	29%	0.294	S	S	.	.	H	α-helix	trans	-64.2	-42.6	174.3	0	0	0	0	0	110.9	D216 E217 A222 G223	D216-A220 VanDerWaalsContact O-CB 3.29Å; D216-A220 WeakPolarHBondContact O-CB 3.49Å; D216-A220 PolarHBondContact O-N 3.36Å; E217-A220 PolarHBondContact O-N 3.46Å; A220-A222 VanDerWaalsContact C-N 3.33Å; A220-G223 PolarHBondContact O-N 3.29Å; A220-G223 VanDerWaalsContact O-N 3.14Å
221	Q	85.5	Confident	83.5	Confident	12 Å²	12	56.1 Å²	56.1	6%	0.056	30%	0.302	C	S	.	.	H	α-helix	trans	-68.7	-31.1	175	-61.4	-59.8	-42.5	0	0	112.6	M136 F162 F172 E217 I218 G223	M136-Q221 HydrophobicContact CB-CB 4.33Å; M136-Q221 HydrophobicContact CB-CG 3.86Å; M136-Q221 HydrophobicContact CE-CG 3.76Å; M136-Q221 HydrophobicContact SD-CB 4.14Å; M136-Q221 HydrophobicContact SD-CG 3.98Å; F162-Q221 WeakPolarHBondContact CD1-O 3.45Å; F172-Q221 HydrophobicContact CE1-CB 4.22Å; F172-Q221 HydrophobicContact CZ-CB 3.62Å; E217-Q221 VanDerWaalsContact O-CG 3.23Å; E217-Q221 WeakPolarHBondContact O-CG 3.42Å; E217-Q221 PolarHBondContact O-N 2.98Å; E217-Q221 PolarHBondContact OE1-NE2 3.23Å; I218-Q221 PolarHBondContact O-N 2.92Å; Q221-G223 PolarHBondContact O-N 3.37Å
222	A	85.2	Confident	83	Confident	7 Å²	7	61.4 Å²	61.4	6%	0.058	32%	0.321	C	S	.	.	T	Hydrogen-bonded Turn	trans	-73.6	-9.9	172.4	0	0	0	0	0	113.6	P163 F172 I218 W219 A220	P163-A222 HydrophobicContact CG-CB 4.33Å; F172-A222 HydrophobicContact CD1-CB 3.86Å; F172-A222 HydrophobicContact CE1-CB 3.84Å; I218-A222 WeakPolarHBondContact O-CB 3.31Å; I218-A222 PolarHBondContact O-N 3.02Å; W219-A222 HydrophobicContact CE3-CB 4.2Å; W219-A222 PolarHBondContact O-N 3.28Å; A220-A222 VanDerWaalsContact C-N 3.33Å
223	G	78.7	Confident	82.8	Confident	23 Å²	23	62.5 Å²	62.5	24%	0.237	33%	0.329	C	S	.	.	T	Hydrogen-bonded Turn	trans	81.2	19.1	177.8	0	0	0	0	0	115.1	F162 W219 A220 Q221 R225	F162-G223 VanDerWaalsContact CD1-N 3.32Å; F162-G223 VanDerWaalsContact CE1-CA 3.42Å; W219-G223 PolarHBondContact O-N 2.93Å; W219-G223 VanDerWaalsContact O-N 3.15Å; A220-G223 PolarHBondContact O-N 3.29Å; A220-G223 VanDerWaalsContact O-N 3.14Å; Q221-G223 PolarHBondContact O-N 3.37Å; G223-R225 PolarHBondContact O-N 2.98Å
224	D	76.2	Confident	82.5	Confident	40 Å²	40	59.4 Å²	59.4	21%	0.214	31%	0.314	C	S	.	.			trans	-69.5	119.1	-178.1	-173	33.4	0	0	0	112.3	W219 S226 K234	W219-D224 HydrophobicContact CB-CB 4.42Å; W219-D224 HydrophobicContact CD2-CB 4.41Å; W219-D224 HydrophobicContact CE3-CB 3.65Å; W219-D224 HydrophobicContact CZ3-CB 4.33Å; W219-D224 PolarHBondContact O-N 3.49Å; W219-D224 VanDerWaalsContact O-N 3.1Å; D224-S226 WeakPolarHBondContact OD1-CB 3.48Å; D224-S226 PolarHBondContact OD1-N 3.45Å; D224-S226 PolarHBondContact OD1-OG 3.44Å; D224-K234 IonicContact OD1-NZ 3.54Å; D224-K234 PolarHBondContact OD1-NZ 3Å; D224-K234 WeakPolarHBondContact OD2-CD 3.49Å; D224-K234 IonicContact OD2-NZ 3.46Å; D224-K234 PolarHBondContact OD2-NZ 3.42Å; D224-K234 VanDerWaalsContact OD2-NZ 3.11Å
225	R	64.5	Low	82.4	Confident	219 Å²	219	61.1 Å²	61.1	83%	0.826	32%	0.32	S	S	*	.			trans	-106.2	16.7	175.6	-64.4	-172.1	-179.3	-179.8	1.2	113.6	G223 T227	G223-R225 PolarHBondContact O-N 2.98Å; R225-T227 PolarHBondContact O-N 3.11Å
226	S	71.4	Confident	82.3	Confident	30 Å²	30	66.8 Å²	66.8	21%	0.21	35%	0.35	C	S	.	.			trans	-67.1	130.4	-177.9	-58.6	0	0	0	0	111.4	D224 K234	D224-S226 WeakPolarHBondContact OD1-CB 3.48Å; D224-S226 PolarHBondContact OD1-N 3.45Å; D224-S226 PolarHBondContact OD1-OG 3.44Å; S226-K234 PolarHBondContact OG-NZ 2.8Å
227	T	65.2	Low	82.4	Confident	124 Å²	124	65.9 Å²	65.9	76%	0.761	35%	0.348	S	S	*	.			trans	-113.3	-2.3	177.7	51.5	0	0	0	0	114.2	R225	R225-T227 PolarHBondContact O-N 3.11Å
228	D	74.9	Confident	82.5	Confident	114 Å²	114	63.2 Å²	63.2	61%	0.61	34%	0.335	S	S	*	.	S	Bend	trans	-91.5	-167.9	-173.7	-57.1	-46.3	0	0	0	112.7	S230 W231	D228-S230 PolarHBondContact O-N 3.47Å; D228-W231 WeakPolarHBondContact O-CB 3.3Å; D228-W231 PolarHBondContact O-N 3.19Å
229	L	74.7	Confident	82.6	Confident	149 Å²	149	64 Å²	64	78%	0.78	34%	0.342	S	S	*	.	H	α-helix	trans	-51.7	-25.4	170.4	-82.5	77.7	0	0	0	112.8	W231 Y232 A233	L229-W231 PolarHBondContact O-N 3.05Å; L229-Y232 PolarHBondContact O-N 3.25Å; L229-A233 PolarHBondContact O-N 3.2Å
230	S	80.7	Confident	82.8	Confident	44 Å²	44	69.3 Å²	69.3	31%	0.308	36%	0.363	S	S	.	.	H	α-helix	trans	-59.1	-31.8	172	57.2	0	0	0	0	113	D228 A233 K234	D228-S230 PolarHBondContact O-N 3.47Å; S230-A233 PolarHBondContact O-N 3.15Å; S230-K234 VanDerWaalsContact O-CB 3.27Å; S230-K234 WeakPolarHBondContact O-CB 3.24Å; S230-K234 WeakPolarHBondContact O-CD 3.36Å; S230-K234 WeakPolarHBondContact O-CG 3.4Å; S230-K234 PolarHBondContact O-N 3.3Å
231	W	81.7	Confident	83.2	Confident	59 Å²	59	66.7 Å²	66.7	22%	0.223	34%	0.341	C	S	.	.	H	α-helix	trans	-59.6	-47.9	174.7	-178.4	95	0	0	0	111.4	I38 D228 L229 R235	I38-W231 HydrophobicContact CG2-CH2 3.86Å; D228-W231 WeakPolarHBondContact O-CB 3.3Å; D228-W231 PolarHBondContact O-N 3.19Å; L229-W231 PolarHBondContact O-N 3.05Å; W231-R235 VanDerWaalsContact CD1-CZ 3.43Å; W231-R235 VanDerWaalsContact NE1-NH2 3.16Å; W231-R235 WeakPolarHBondContact O-CG 3.17Å; W231-R235 PolarHBondContact O-N 2.87Å; W231-R235 PolarHBondContact O-NH1 3.33Å
232	Y	84.4	Confident	83.6	Confident	141 Å²	141	66.2 Å²	66.2	55%	0.553	34%	0.339	S	S	*	.	H	α-helix	trans	-68.5	-46.4	178.3	-69.8	-82.3	0	0	0	111.2	L229 K234 R235 L236	L229-Y232 PolarHBondContact O-N 3.25Å; Y232-K234 VanDerWaalsContact C-N 3.32Å; Y232-K234 PolarHBondContact O-N 3.42Å; Y232-R235 PolarHBondContact O-N 2.95Å; Y232-L236 WeakPolarHBondContact O-CB 3.27Å; Y232-L236 WeakPolarHBondContact O-CG 3.09Å; Y232-L236 PolarHBondContact O-N 3.27Å
233	A	86.5	Confident	84	Confident	65 Å²	65	68.8 Å²	68.8	54%	0.537	35%	0.352	S	S	.	.	H	α-helix	trans	-61	-40.6	-178.9	0	0	0	0	0	112.2	L229 S230 G237	L229-A233 PolarHBondContact O-N 3.2Å; S230-A233 PolarHBondContact O-N 3.15Å; A233-G237 WeakPolarHBondContact O-CA 3.45Å; A233-G237 PolarHBondContact O-N 3.02Å
234	K	87.3	Confident	84.8	Confident	47 Å²	47	70 Å²	70	20%	0.204	35%	0.352	C	S	.	.	H	α-helix	trans	-64.9	-44.8	177.5	-79.1	174.1	174.7	178.5	0	112.9	W219 D224 S226 S230 Y232 G237 V238	W219-K234 HydrophobicContact CD2-CB 4.47Å; W219-K234 HydrophobicContact CH2-CB 4.28Å; W219-K234 HydrophobicContact CH2-CD 4.03Å; W219-K234 HydrophobicContact CH2-CG 3.99Å; W219-K234 HydrophobicContact CZ2-CB 3.62Å; W219-K234 HydrophobicContact CZ2-CD 4.2Å; W219-K234 HydrophobicContact CZ2-CG 3.82Å; W219-K234 HydrophobicContact CZ3-CD 4.21Å; W219-K234 PolarHBondContact NE1-O 3.1Å; D224-K234 IonicContact OD1-NZ 3.54Å; D224-K234 PolarHBondContact OD1-NZ 3Å; D224-K234 WeakPolarHBondContact OD2-CD 3.49Å; D224-K234 IonicContact OD2-NZ 3.46Å; D224-K234 PolarHBondContact OD2-NZ 3.42Å; D224-K234 VanDerWaalsContact OD2-NZ 3.11Å; S226-K234 PolarHBondContact OG-NZ 2.8Å; S230-K234 VanDerWaalsContact O-CB 3.27Å; S230-K234 WeakPolarHBondContact O-CB 3.24Å; S230-K234 WeakPolarHBondContact O-CD 3.36Å; S230-K234 WeakPolarHBondContact O-CG 3.4Å; S230-K234 PolarHBondContact O-N 3.3Å; Y232-K234 VanDerWaalsContact C-N 3.32Å; Y232-K234 PolarHBondContact O-N 3.42Å; K234-G237 PolarHBondContact O-N 2.98Å; K234-V238 WeakPolarHBondContact O-CG2 3.44Å; K234-V238 PolarHBondContact O-N 3.35Å
235	R	90.5	Very high	85.7	Confident	40 Å²	40	68.1 Å²	68.1	15%	0.151	34%	0.342	C	S	.	.	H	α-helix	trans	-67.1	-49.7	179	-76	166.5	173.1	62.8	8.6	111.8	V215 D216 W231 Y232 G237 V238 A239	V215-R235 HydrophobicContact CG1-CB 4.08Å; V215-R235 HydrophobicContact CG1-CG 4.02Å; D216-R235 IonicContact OD1-CZ 3.84Å; D216-R235 IonicContact OD1-NE 2.75Å; D216-R235 PolarHBondContact OD1-NE 3.49Å; D216-R235 IonicContact OD1-NH2 2.73Å; D216-R235 PolarHBondContact OD1-NH2 3.27Å; W231-R235 VanDerWaalsContact CD1-CZ 3.43Å; W231-R235 VanDerWaalsContact NE1-NH2 3.16Å; W231-R235 WeakPolarHBondContact O-CG 3.17Å; W231-R235 PolarHBondContact O-N 2.87Å; W231-R235 PolarHBondContact O-NH1 3.33Å; Y232-R235 PolarHBondContact O-N 2.95Å; R235-G237 VanDerWaalsContact C-N 3.26Å; R235-G237 PolarHBondContact O-N 3.3Å; R235-V238 PolarHBondContact O-N 3.36Å; R235-A239 VanDerWaalsContact O-CB 3.23Å; R235-A239 WeakPolarHBondContact O-CB 3.39Å; R235-A239 PolarHBondContact O-N 3Å
236	L	91.1	Very high	87.1	Confident	123 Å²	123	58 Å²	58	64%	0.644	30%	0.304	S	S	*	.	H	α-helix	trans	-61.4	-38.5	176.6	-71.3	176.6	0	0	0	111.4	Y232 Y240	Y232-L236 WeakPolarHBondContact O-CB 3.27Å; Y232-L236 WeakPolarHBondContact O-CG 3.09Å; Y232-L236 PolarHBondContact O-N 3.27Å; L236-Y240 WeakPolarHBondContact O-CB 3.35Å; L236-Y240 PolarHBondContact O-N 3.48Å
237	G	92.3	Very high	88.2	Confident	11 Å²	11	60.9 Å²	60.9	11%	0.113	32%	0.317	C	S	.	.	H	α-helix	trans	-59.8	-54.3	175.6	0	0	0	0	0	112.5	A233 K234 R235 Y240 V241	A233-G237 WeakPolarHBondContact O-CA 3.45Å; A233-G237 PolarHBondContact O-N 3.02Å; K234-G237 PolarHBondContact O-N 2.98Å; R235-G237 VanDerWaalsContact C-N 3.26Å; R235-G237 PolarHBondContact O-N 3.3Å; G237-Y240 WeakPolarHBondContact O-CB 3.23Å; G237-Y240 PolarHBondContact O-N 3.29Å; G237-V241 WeakPolarHBondContact O-CG2 3.29Å; G237-V241 PolarHBondContact O-N 2.83Å
238	V	92.9	Very high	89.6	Confident	2 Å²	2	58.6 Å²	58.6	1%	0.012	30%	0.295	C	S	.	.	H	α-helix	trans	-66.7	-40.1	-179.7	175.6	0	0	0	0	111.8	L173 L177 V215 W219 K234 R235 Y240 V241 Y242 L271	L173-V238 HydrophobicContact CD1-CG2 4.41Å; L173-V238 HydrophobicContact CD2-CG2 4.03Å; L177-V238 HydrophobicContact CD1-CG1 4.47Å; L177-V238 HydrophobicContact CD2-CG1 4.26Å; V215-V238 HydrophobicContact CG1-CB 3.98Å; V215-V238 HydrophobicContact CG1-CG1 4.16Å; V215-V238 HydrophobicContact CG2-CG1 4.18Å; W219-V238 HydrophobicContact CZ2-CG2 3.63Å; W219-V238 VanDerWaalsContact NE1-CG2 3.34Å; K234-V238 WeakPolarHBondContact O-CG2 3.44Å; K234-V238 PolarHBondContact O-N 3.35Å; R235-V238 PolarHBondContact O-N 3.36Å; V238-Y240 VanDerWaalsContact C-N 3.32Å; V238-Y240 PolarHBondContact O-N 2.84Å; V238-V241 PolarHBondContact O-N 3.25Å; V238-Y242 WeakPolarHBondContact O-CB 3.44Å; V238-Y242 PolarHBondContact O-N 2.96Å; V238-L271 HydrophobicContact CG2-CD1 4.49Å
239	A	93.9	Very high	90.4	Very high	16 Å²	16	53.1 Å²	53.1	13%	0.132	27%	0.266	C	S	.	.	H	α-helix	trans	-59.2	-42.8	174.3	0	0	0	0	0	111.9	L211 V215 R235 Y242 N243	L211-A239 HydrophobicContact CD2-CB 4.18Å; L211-A239 HydrophobicContact CG-CB 4.38Å; V215-A239 HydrophobicContact CG2-CB 4.04Å; R235-A239 VanDerWaalsContact O-CB 3.23Å; R235-A239 WeakPolarHBondContact O-CB 3.39Å; R235-A239 PolarHBondContact O-N 3Å; A239-Y242 PolarHBondContact O-N 3.5Å; A239-N243 WeakPolarHBondContact O-CB 3.45Å; A239-N243 PolarHBondContact O-N 3.49Å; A239-N243 PolarHBondContact O-ND2 2.96Å
240	Y	94	Very high	91.2	Very high	133 Å²	133	48.4 Å²	48.4	52%	0.522	24%	0.241	S	C	.	.	H	α-helix	trans	-62.8	-47.3	176.5	172.7	-104.6	0	0	0	111.7	L236 G237 V238 L244	L236-Y240 WeakPolarHBondContact O-CB 3.35Å; L236-Y240 PolarHBondContact O-N 3.48Å; G237-Y240 WeakPolarHBondContact O-CB 3.23Å; G237-Y240 PolarHBondContact O-N 3.29Å; V238-Y240 VanDerWaalsContact C-N 3.32Å; V238-Y240 PolarHBondContact O-N 2.84Å; Y240-L244 HydrophobicContact CD1-CD1 3.98Å; Y240-L244 HydrophobicContact CD2-CD1 4.13Å; Y240-L244 HydrophobicContact CD2-CG 4.15Å; Y240-L244 HydrophobicContact CE1-CD1 3.37Å; Y240-L244 HydrophobicContact CE1-CG 4.34Å; Y240-L244 HydrophobicContact CE2-CD1 3.54Å; Y240-L244 HydrophobicContact CE2-CD2 4.3Å; Y240-L244 HydrophobicContact CE2-CG 3.87Å; Y240-L244 HydrophobicContact CG-CD1 4.34Å; Y240-L244 VanDerWaalsContact O-CB 3.32Å; Y240-L244 WeakPolarHBondContact O-CB 3.21Å; Y240-L244 WeakPolarHBondContact O-CG 3.19Å; Y240-L244 PolarHBondContact O-N 3.17Å; Y240-L244 WeakPolarHBondContact OH-CD1 3.44Å
241	V	94.9	Very high	91.7	Very high	1 Å²	1	53.8 Å²	53.8	1%	0.006	26%	0.261	C	S	.	.	H	α-helix	trans	-61.5	-46.9	177.4	173.9	0	0	0	0	111.1	L177 G237 V238 L244 T245 L264 R267 I268 L271	L177-V241 HydrophobicContact CD1-CG1 4.14Å; G237-V241 WeakPolarHBondContact O-CG2 3.29Å; G237-V241 PolarHBondContact O-N 2.83Å; V238-V241 PolarHBondContact O-N 3.25Å; V241-L244 PolarHBondContact O-N 3.13Å; V241-T245 WeakPolarHBondContact O-CB 3.48Å; V241-T245 PolarHBondContact O-N 3.46Å; V241-T245 PolarHBondContact O-OG1 2.96Å; V241-L264 HydrophobicContact CG1-CD1 3.62Å; V241-R267 HydrophobicContact CB-CB 4.39Å; V241-R267 HydrophobicContact CG1-CB 3.78Å; V241-R267 HydrophobicContact CG2-CB 3.91Å; V241-I268 HydrophobicContact CG1-CG1 4.14Å; V241-L271 HydrophobicContact CG2-CD1 3.59Å; V241-L271 HydrophobicContact CG2-CD2 4.08Å; V241-L271 HydrophobicContact CG2-CG 3.79Å
242	Y	94.9	Very high	92.2	Very high	2 Å²	2	52.1 Å²	52.1	1%	0.008	26%	0.257	C	S	.	.	H	α-helix	trans	-56.4	-54.6	177.7	175.1	-94.2	0	0	0	111.7	L177 R180 L181 L211 L214 V238 A239 L244 T245 E246	L177-Y242 HydrophobicContact CD2-CD2 3.88Å; L177-Y242 HydrophobicContact CD2-CG 4.4Å; R180-Y242 HydrophobicContact CG-CE2 3.76Å; R180-Y242 PolarHBondContact NH1-OH 3.49Å; L181-Y242 HydrophobicContact CD2-CE2 4.12Å; L181-Y242 HydrophobicContact CG-CE2 4.41Å; L211-Y242 HydrophobicContact CD1-CD1 3.55Å; L211-Y242 HydrophobicContact CD1-CE1 4.01Å; L211-Y242 HydrophobicContact CD1-CG 4.33Å; L214-Y242 HydrophobicContact CD2-CD2 4.29Å; L214-Y242 HydrophobicContact CD2-CE1 4.44Å; L214-Y242 HydrophobicContact CD2-CE2 4.07Å; V238-Y242 WeakPolarHBondContact O-CB 3.44Å; V238-Y242 PolarHBondContact O-N 2.96Å; A239-Y242 PolarHBondContact O-N 3.5Å; Y242-L244 PolarHBondContact O-N 2.84Å; Y242-T245 PolarHBondContact O-N 3.38Å; Y242-E246 WeakPolarHBondContact CE1-OE2 3.25Å; Y242-E246 WeakPolarHBondContact O-CB 3.28Å; Y242-E246 PolarHBondContact O-N 3.11Å; Y242-E246 PolarHBondContact OH-OE1 3.41Å
243	N	94.3	Very high	92.3	Very high	62 Å²	62	55.1 Å²	55.1	33%	0.332	27%	0.273	S	S	.	.	H	α-helix	trans	-63.8	-40.3	-177.9	-73.5	-20.2	0	0	0	112.1	L211 A239 E246 L247	L211-N243 VanDerWaalsContact CD2-ND2 3.27Å; L211-N243 WeakPolarHBondContact CD2-ND2 3.21Å; A239-N243 WeakPolarHBondContact O-CB 3.45Å; A239-N243 PolarHBondContact O-N 3.49Å; A239-N243 PolarHBondContact O-ND2 2.96Å; N243-E246 PolarHBondContact O-N 3.32Å; N243-L247 WeakPolarHBondContact O-CB 3.48Å; N243-L247 VanDerWaalsContact O-CG 3.28Å; N243-L247 WeakPolarHBondContact O-CG 3.36Å; N243-L247 PolarHBondContact O-N 2.93Å
244	L	94.4	Very high	92.5	Very high	49 Å²	49	53.3 Å²	53.3	26%	0.257	26%	0.256	S	S	.	.	H	α-helix	trans	-65.5	-43.1	177	-79.2	-169.5	0	0	0	112.4	Y240 V241 Y242 L247 Y248 F263	Y240-L244 HydrophobicContact CD1-CD1 3.98Å; Y240-L244 HydrophobicContact CD2-CD1 4.13Å; Y240-L244 HydrophobicContact CD2-CG 4.15Å; Y240-L244 HydrophobicContact CE1-CD1 3.37Å; Y240-L244 HydrophobicContact CE1-CG 4.34Å; Y240-L244 HydrophobicContact CE2-CD1 3.54Å; Y240-L244 HydrophobicContact CE2-CD2 4.3Å; Y240-L244 HydrophobicContact CE2-CG 3.87Å; Y240-L244 HydrophobicContact CG-CD1 4.34Å; Y240-L244 VanDerWaalsContact O-CB 3.32Å; Y240-L244 WeakPolarHBondContact O-CB 3.21Å; Y240-L244 WeakPolarHBondContact O-CG 3.19Å; Y240-L244 PolarHBondContact O-N 3.17Å; Y240-L244 WeakPolarHBondContact OH-CD1 3.44Å; V241-L244 PolarHBondContact O-N 3.13Å; Y242-L244 PolarHBondContact O-N 2.84Å; L244-L247 PolarHBondContact O-N 3.24Å; L244-Y248 WeakPolarHBondContact O-CB 3.28Å; L244-Y248 PolarHBondContact O-N 3.39Å; L244-F263 HydrophobicContact CB-CE1 4.15Å; L244-F263 HydrophobicContact CB-CZ 4.35Å
245	T	95.1	Very high	92.5	Very high	0 Å²	0	56.2 Å²	56.2	0%	0	28%	0.279	C	S	.	.	H	α-helix	trans	-67.7	-39.3	178	-59	0	0	0	0	110.8	L181 V241 Y242 L247 Y248 M249 L264	L181-T245 HydrophobicContact CD1-CG2 3.39Å; V241-T245 WeakPolarHBondContact O-CB 3.48Å; V241-T245 PolarHBondContact O-N 3.46Å; V241-T245 PolarHBondContact O-OG1 2.96Å; Y242-T245 PolarHBondContact O-N 3.38Å; T245-L247 VanDerWaalsContact C-N 3.35Å; T245-L247 PolarHBondContact O-N 3.25Å; T245-Y248 PolarHBondContact O-N 2.83Å; T245-M249 WeakPolarHBondContact O-CB 3.34Å; T245-M249 PolarHBondContact O-N 3.08Å; T245-L264 HydrophobicContact CG2-CB 3.96Å; T245-L264 HydrophobicContact CG2-CD1 4.22Å
246	E	94.3	Very high	92.2	Very high	5 Å²	5	63.1 Å²	63.1	2%	0.023	31%	0.313	C	S	.	.	H	α-helix	trans	-58.6	-45	173.9	-176.9	173.3	-135.6	0	0	111.6	Y125 L181 I184 W191 Y242 N243 M249	Y125-E246 PolarHBondContact OH-OE1 2.78Å; Y125-E246 VanDerWaalsContact OH-OE1 3.1Å; L181-E246 HydrophobicContact CD2-CB 4.04Å; I184-E246 HydrophobicContact CD1-CG 4.5Å; I184-E246 WeakPolarHBondContact CD1-OE1 3.18Å; W191-E246 VanDerWaalsContact CZ2-OE1 3.31Å; W191-E246 WeakPolarHBondContact CZ2-OE1 3.24Å; W191-E246 PolarHBondContact NE1-OE1 2.95Å; Y242-E246 WeakPolarHBondContact CE1-OE2 3.25Å; Y242-E246 WeakPolarHBondContact O-CB 3.28Å; Y242-E246 PolarHBondContact O-N 3.11Å; Y242-E246 PolarHBondContact OH-OE1 3.41Å; N243-E246 PolarHBondContact O-N 3.32Å; E246-M249 PolarHBondContact O-N 2.74Å
247	L	94	Very high	92	Very high	92 Å²	92	58 Å²	58	48%	0.482	29%	0.287	S	S	.	.	H	α-helix	trans	-67.4	-39.1	175.7	-70.6	173.8	0	0	0	113	L195 N243 L244 T245 M249 L250	L195-L247 HydrophobicContact CD1-CD2 4.19Å; N243-L247 WeakPolarHBondContact O-CB 3.48Å; N243-L247 VanDerWaalsContact O-CG 3.28Å; N243-L247 WeakPolarHBondContact O-CG 3.36Å; N243-L247 PolarHBondContact O-N 2.93Å; L244-L247 PolarHBondContact O-N 3.24Å; T245-L247 VanDerWaalsContact C-N 3.35Å; T245-L247 PolarHBondContact O-N 3.25Å; L247-M249 VanDerWaalsContact C-N 3.33Å; L247-L250 HydrophobicContact CD2-CD1 4.3Å; L247-L250 WeakPolarHBondContact O-CB 3.37Å; L247-L250 PolarHBondContact O-N 3.39Å
248	Y	93.8	Very high	92	Very high	75 Å²	75	59.7 Å²	59.7	29%	0.294	30%	0.297	S	S	.	.	H	α-helix	trans	-64.1	-40.5	177.6	-173.2	-94.2	0	0	0	111.5	L244 T245 L250 Q251 D252 E259 F263	L244-Y248 WeakPolarHBondContact O-CB 3.28Å; L244-Y248 PolarHBondContact O-N 3.39Å; T245-Y248 PolarHBondContact O-N 2.83Å; Y248-L250 PolarHBondContact O-N 2.89Å; Y248-Q251 PolarHBondContact O-N 3.36Å; Y248-D252 PolarHBondContact O-N 2.97Å; Y248-D252 VanDerWaalsContact O-N 3.15Å; Y248-E259 HydrophobicContact CE1-CB 4.21Å; Y248-F263 HydrophobicContact CD1-CB 4.01Å; Y248-F263 HydrophobicContact CD1-CD1 4.32Å; Y248-F263 HydrophobicContact CD1-CD2 4.46Å; Y248-F263 HydrophobicContact CD1-CG 4.04Å; Y248-F263 AromaticContact CD2-CD2 3.92Å; Y248-F263 HydrophobicContact CD2-CD2 3.92Å; Y248-F263 AromaticContact CD2-CE2 3.99Å; Y248-F263 HydrophobicContact CD2-CE2 3.99Å; Y248-F263 HydrophobicContact CD2-CG 4.27Å; Y248-F263 HydrophobicContact CD2-CZ 4.41Å; Y248-F263 HydrophobicContact CE1-CB 3.95Å; Y248-F263 HydrophobicContact CE1-CG 4.3Å; Y248-F263 HydrophobicContact CE2-CD2 4Å; Y248-F263 HydrophobicContact CE2-CE2 4.36Å; Y248-F263 HydrophobicContact CG-CB 4.48Å; Y248-F263 HydrophobicContact CG-CD1 4.12Å; Y248-F263 HydrophobicContact CG-CD2 4.15Å; Y248-F263 HydrophobicContact CG-CE1 4.38Å; Y248-F263 HydrophobicContact CG-CE2 4.38Å; Y248-F263 HydrophobicContact CG-CG 4.01Å
249	M	92	Very high	92	Very high	0 Å²	0	63.5 Å²	63.5	0%	0	31%	0.314	C	S	.	.	H	α-helix	trans	-61.7	-26.6	179.4	-164.4	173.9	70.1	0	0	113.1	L181 I184 L188 T245 E246 L247 Q251 L257	L181-M249 HydrophobicContact CB-SD 4.31Å; L181-M249 HydrophobicContact CD2-CE 4.25Å; I184-M249 HydrophobicContact CB-CE 4.03Å; I184-M249 HydrophobicContact CG2-CE 4Å; L188-M249 HydrophobicContact CD1-CE 3.73Å; L188-M249 HydrophobicContact CD1-CG 3.95Å; L188-M249 HydrophobicContact CD1-SD 4.48Å; T245-M249 WeakPolarHBondContact O-CB 3.34Å; T245-M249 PolarHBondContact O-N 3.08Å; E246-M249 PolarHBondContact O-N 2.74Å; L247-M249 VanDerWaalsContact C-N 3.33Å; M249-Q251 VanDerWaalsContact C-N 3.29Å; M249-Q251 PolarHBondContact O-N 3.45Å; M249-L257 HydrophobicContact CG-CD1 3.81Å; M249-L257 HydrophobicContact CG-CD2 4.02Å; M249-L257 HydrophobicContact CG-CG 4.42Å; M249-L257 HydrophobicContact SD-CD1 3.95Å
250	L	91.8	Very high	91.9	Very high	50 Å²	50	62.7 Å²	62.7	26%	0.262	31%	0.308	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.3	-26.7	174.7	-64.4	173.9	0	0	0	113.5	L188 W191 P192 L195 L247 Y248	L188-L250 HydrophobicContact CD1-CD2 4.19Å; W191-L250 HydrophobicContact CB-CD2 3.92Å; W191-L250 HydrophobicContact CG-CD2 4.3Å; P192-L250 HydrophobicContact CG-CD1 4.32Å; P192-L250 HydrophobicContact CG-CD2 3.89Å; L195-L250 HydrophobicContact CD1-CD1 3.65Å; L247-L250 HydrophobicContact CD2-CD1 4.3Å; L247-L250 WeakPolarHBondContact O-CB 3.37Å; L247-L250 PolarHBondContact O-N 3.39Å; Y248-L250 PolarHBondContact O-N 2.89Å
251	Q	91.5	Very high	91.9	Very high	157 Å²	157	57.9 Å²	57.9	73%	0.734	29%	0.289	S	S	*	.	T	Hydrogen-bonded Turn	trans	-97.7	-15.4	-177.9	-62.5	-177.1	-13.4	0	0	112.2	Y248 M249 K253	Y248-Q251 PolarHBondContact O-N 3.36Å; M249-Q251 VanDerWaalsContact C-N 3.29Å; M249-Q251 PolarHBondContact O-N 3.45Å; Q251-K253 PolarHBondContact O-N 3.03Å
252	D	91.5	Very high	91.9	Very high	23 Å²	23	61.2 Å²	61.2	12%	0.123	31%	0.306	C	S	.	.			trans	-72.3	124.8	-175.7	-166.2	3.4	0	0	0	111.4	Y248 S254 L257 S260	Y248-D252 PolarHBondContact O-N 2.97Å; Y248-D252 VanDerWaalsContact O-N 3.15Å; D252-S254 VanDerWaalsContact OD1-CB 3.24Å; D252-S254 WeakPolarHBondContact OD1-CB 3.37Å; D252-S254 PolarHBondContact OD1-N 3.19Å; D252-S254 PolarHBondContact OD1-OG 3.32Å; D252-L257 HydrophobicContact CB-CD2 3.85Å; D252-L257 WeakPolarHBondContact OD2-CA 3.34Å; D252-S260 WeakPolarHBondContact CB-OG 3.31Å; D252-S260 WeakPolarHBondContact OD2-CB 3.48Å; D252-S260 PolarHBondContact OD2-N 3.44Å; D252-S260 PolarHBondContact OD2-OG 3.33Å
253	K	88	Confident	91.9	Very high	205 Å²	205	62.9 Å²	62.9	89%	0.891	31%	0.313	S	S	*	.			trans	-113.1	8.5	176.7	-62.1	-176.7	-177.9	179.8	0	111.9	Q251	Q251-K253 PolarHBondContact O-N 3.03Å
254	S	90.2	Very high	91.8	Very high	27 Å²	27	59.9 Å²	59.9	19%	0.189	30%	0.297	C	S	.	.	S	Bend	trans	-69.7	154.4	-179.6	92.3	0	0	0	0	111.1	D252 E256 L257 S258 E259	D252-S254 VanDerWaalsContact OD1-CB 3.24Å; D252-S254 WeakPolarHBondContact OD1-CB 3.37Å; D252-S254 PolarHBondContact OD1-N 3.19Å; D252-S254 PolarHBondContact OD1-OG 3.32Å; S254-E256 PolarHBondContact O-N 3.27Å; S254-L257 PolarHBondContact O-N 3.24Å; S254-S258 PolarHBondContact OG-N 3.35Å; S254-S258 PolarHBondContact OG-OG 3.36Å; S254-E259 PolarHBondContact OG-N 3.38Å
255	P	86.2	Confident	91.8	Very high	107 Å²	107	63.1 Å²	63.1	70%	0.695	31%	0.306	S	S	*	.	G	3₁₀ helix	trans	-60.2	132.9	172.7	26.7	-33.8	0	0	0	109.8	L257 S258	P255-L257 PolarHBondContact O-N 3Å; P255-S258 PolarHBondContact O-N 3.37Å
256	E	85.1	Confident	91.7	Very high	185 Å²	185	68.3 Å²	68.3	86%	0.864	33%	0.329	S	S	*	.	G	3₁₀ helix	trans	55.3	18.3	-179.7	-55.9	-165.6	132.6	0	0	116.2	S254 S258 W261	S254-E256 PolarHBondContact O-N 3.27Å; E256-S258 PolarHBondContact O-N 2.97Å; E256-W261 PolarHBondContact O-NE1 3.25Å; E256-W261 VanDerWaalsContact O-NE1 3.14Å
257	L	87.9	Confident	91.7	Very high	17 Å²	17	70.7 Å²	70.7	9%	0.089	34%	0.337	C	S	.	.	G	3₁₀ helix	trans	58.7	31.2	-176.9	-55.4	162.1	0	0	0	112.7	I185 L188 M249 D252 S254 P255 E259 S260 W261	I185-L257 HydrophobicContact CD1-CD1 4.02Å; I185-L257 HydrophobicContact CG1-CD1 3.92Å; L188-L257 HydrophobicContact CD2-CD2 4.42Å; M249-L257 HydrophobicContact CG-CD1 3.81Å; M249-L257 HydrophobicContact CG-CD2 4.02Å; M249-L257 HydrophobicContact CG-CG 4.42Å; M249-L257 HydrophobicContact SD-CD1 3.95Å; D252-L257 HydrophobicContact CB-CD2 3.85Å; D252-L257 WeakPolarHBondContact OD2-CA 3.34Å; S254-L257 PolarHBondContact O-N 3.24Å; P255-L257 PolarHBondContact O-N 3Å; L257-E259 PolarHBondContact O-N 3.2Å; L257-S260 VanDerWaalsContact O-CB 3.31Å; L257-S260 WeakPolarHBondContact O-CB 3.29Å; L257-S260 PolarHBondContact O-N 3Å; L257-W261 PolarHBondContact O-N 3.3Å; L257-W261 PolarHBondContact O-NE1 3.03Å
258	S	90.4	Very high	91.6	Very high	45 Å²	45	66.6 Å²	66.6	32%	0.315	32%	0.316	S	S	.	.	H	α-helix	trans	-49.7	-40.7	179.5	63.6	0	0	0	0	113.4	S254 P255 E256 W261 I262	S254-S258 PolarHBondContact OG-N 3.35Å; S254-S258 PolarHBondContact OG-OG 3.36Å; P255-S258 PolarHBondContact O-N 3.37Å; E256-S258 PolarHBondContact O-N 2.97Å; S258-W261 PolarHBondContact O-N 2.91Å; S258-I262 WeakPolarHBondContact O-CG1 3.45Å; S258-I262 PolarHBondContact O-N 3.39Å; S258-I262 VanDerWaalsContact O-N 3.14Å
259	E	93	Very high	91.4	Very high	82 Å²	82	67.3 Å²	67.3	38%	0.383	32%	0.322	S	S	.	.	H	α-helix	trans	-69.4	-35.8	-179.2	-68.3	-55.1	125.2	0	0	111.5	Y248 S254 L257 W261 I262 F263	Y248-E259 HydrophobicContact CE1-CB 4.21Å; S254-E259 PolarHBondContact OG-N 3.38Å; L257-E259 PolarHBondContact O-N 3.2Å; E259-W261 VanDerWaalsContact C-N 3.32Å; E259-W261 PolarHBondContact O-N 3.34Å; E259-I262 PolarHBondContact O-N 3.38Å; E259-F263 VanDerWaalsContact O-CB 3.29Å; E259-F263 WeakPolarHBondContact O-CB 3.44Å; E259-F263 PolarHBondContact O-N 3.03Å
260	S	93.4	Very high	91.2	Very high	0 Å²	0	70.4 Å²	70.4	0%	0	34%	0.339	C	S	.	.	H	α-helix	trans	-61.2	-39.5	174.3	-61.9	0	0	0	0	112.4	D252 L257 F263 L264	D252-S260 WeakPolarHBondContact CB-OG 3.31Å; D252-S260 WeakPolarHBondContact OD2-CB 3.48Å; D252-S260 PolarHBondContact OD2-N 3.44Å; D252-S260 PolarHBondContact OD2-OG 3.33Å; L257-S260 VanDerWaalsContact O-CB 3.31Å; L257-S260 WeakPolarHBondContact O-CB 3.29Å; L257-S260 PolarHBondContact O-N 3Å; S260-F263 WeakPolarHBondContact O-CB 3.45Å; S260-F263 PolarHBondContact O-N 3.24Å; S260-L264 WeakPolarHBondContact O-CB 3.46Å; S260-L264 PolarHBondContact O-N 3.29Å
261	W	93.8	Very high	90.9	Very high	31 Å²	31	69.9 Å²	69.9	12%	0.117	34%	0.336	C	S	.	.	H	α-helix	trans	-71.7	-37.8	178.1	-53.5	125.9	0	0	0	112.6	E178 L181 K182 I185 E256 L257 S258 E259 F263 L264 R265	E178-W261 HydrophobicContact CB-CE3 4.36Å; E178-W261 HydrophobicContact CB-CZ3 4.11Å; E178-W261 HydrophobicContact CG-CD2 4.49Å; E178-W261 HydrophobicContact CG-CE3 3.94Å; E178-W261 HydrophobicContact CG-CH2 4.16Å; E178-W261 HydrophobicContact CG-CZ3 3.79Å; L181-W261 HydrophobicContact CB-CH2 3.91Å; L181-W261 HydrophobicContact CB-CZ3 3.97Å; L181-W261 HydrophobicContact CD1-CZ3 4.11Å; K182-W261 HydrophobicContact CG-CH2 3.8Å; K182-W261 HydrophobicContact CG-CZ2 3.89Å; I185-W261 HydrophobicContact CD1-CZ2 4.29Å; E256-W261 PolarHBondContact O-NE1 3.25Å; E256-W261 VanDerWaalsContact O-NE1 3.14Å; L257-W261 PolarHBondContact O-N 3.3Å; L257-W261 PolarHBondContact O-NE1 3.03Å; S258-W261 PolarHBondContact O-N 2.91Å; E259-W261 VanDerWaalsContact C-N 3.32Å; E259-W261 PolarHBondContact O-N 3.34Å; W261-F263 VanDerWaalsContact C-N 3.34Å; W261-L264 HydrophobicContact CE3-CD2 4.18Å; W261-L264 HydrophobicContact CZ3-CD2 4.42Å; W261-L264 PolarHBondContact O-N 3.14Å; W261-R265 PolarHBondContact O-N 3.41Å; W261-R265 VanDerWaalsContact O-N 3.1Å
262	I	94.1	Very high	90.3	Very high	72 Å²	72	67 Å²	67	37%	0.369	32%	0.318	S	S	.	.	H	α-helix	trans	-64.3	-42.6	172.1	-66.3	166.5	0	0	0	110.1	S258 E259 R265 K266	S258-I262 WeakPolarHBondContact O-CG1 3.45Å; S258-I262 PolarHBondContact O-N 3.39Å; S258-I262 VanDerWaalsContact O-N 3.14Å; E259-I262 PolarHBondContact O-N 3.38Å; I262-R265 PolarHBondContact O-N 3.22Å; I262-K266 HydrophobicContact CG2-CD 4.23Å; I262-K266 WeakPolarHBondContact O-CG 3.13Å; I262-K266 PolarHBondContact O-N 3.43Å; I262-K266 VanDerWaalsContact O-N 3.08Å
263	F	94.3	Very high	89.5	Confident	36 Å²	36	68.7 Å²	68.7	16%	0.158	33%	0.332	C	S	.	.	H	α-helix	trans	-59.9	-47.8	176	179.3	-89.3	0	0	0	111.3	L244 Y248 E259 S260 W261 R265 K266 R267	L244-F263 HydrophobicContact CB-CE1 4.15Å; L244-F263 HydrophobicContact CB-CZ 4.35Å; Y248-F263 HydrophobicContact CD1-CB 4.01Å; Y248-F263 HydrophobicContact CD1-CD1 4.32Å; Y248-F263 HydrophobicContact CD1-CD2 4.46Å; Y248-F263 HydrophobicContact CD1-CG 4.04Å; Y248-F263 AromaticContact CD2-CD2 3.92Å; Y248-F263 HydrophobicContact CD2-CD2 3.92Å; Y248-F263 AromaticContact CD2-CE2 3.99Å; Y248-F263 HydrophobicContact CD2-CE2 3.99Å; Y248-F263 HydrophobicContact CD2-CG 4.27Å; Y248-F263 HydrophobicContact CD2-CZ 4.41Å; Y248-F263 HydrophobicContact CE1-CB 3.95Å; Y248-F263 HydrophobicContact CE1-CG 4.3Å; Y248-F263 HydrophobicContact CE2-CD2 4Å; Y248-F263 HydrophobicContact CE2-CE2 4.36Å; Y248-F263 HydrophobicContact CG-CB 4.48Å; Y248-F263 HydrophobicContact CG-CD1 4.12Å; Y248-F263 HydrophobicContact CG-CD2 4.15Å; Y248-F263 HydrophobicContact CG-CE1 4.38Å; Y248-F263 HydrophobicContact CG-CE2 4.38Å; Y248-F263 HydrophobicContact CG-CG 4.01Å; E259-F263 VanDerWaalsContact O-CB 3.29Å; E259-F263 WeakPolarHBondContact O-CB 3.44Å; E259-F263 PolarHBondContact O-N 3.03Å; S260-F263 WeakPolarHBondContact O-CB 3.45Å; S260-F263 PolarHBondContact O-N 3.24Å; W261-F263 VanDerWaalsContact C-N 3.34Å; F263-R265 VanDerWaalsContact C-N 3.34Å; F263-R265 PolarHBondContact O-N 3.47Å; F263-K266 PolarHBondContact O-N 3.45Å; F263-R267 HydrophobicContact CD1-CG 3.87Å; F263-R267 HydrophobicContact CE1-CG 3.5Å; F263-R267 HydrophobicContact CE2-CG 4.42Å; F263-R267 HydrophobicContact CG-CG 4.45Å; F263-R267 HydrophobicContact CZ-CG 3.81Å; F263-R267 WeakPolarHBondContact O-CG 3.2Å; F263-R267 PolarHBondContact O-N 2.63Å
264	L	94	Very high	88.7	Confident	0 Å²	0	64.2 Å²	64.2	0%	0	32%	0.315	C	S	.	.	H	α-helix	trans	-54.6	-48.5	176.4	177.5	59.8	0	0	0	111.8	Y174 L177 E178 L181 V241 T245 S260 W261 K266 R267 I268	Y174-L264 HydrophobicContact CD2-CD2 4.02Å; Y174-L264 HydrophobicContact CD2-CG 4.08Å; Y174-L264 HydrophobicContact CE2-CD2 4.07Å; Y174-L264 HydrophobicContact CE2-CG 4.29Å; L177-L264 HydrophobicContact CB-CD1 4.13Å; L177-L264 HydrophobicContact CB-CD2 4.13Å; L177-L264 HydrophobicContact CD1-CD1 3.9Å; E178-L264 HydrophobicContact CB-CD2 4.42Å; L181-L264 HydrophobicContact CD1-CD2 4.38Å; V241-L264 HydrophobicContact CG1-CD1 3.62Å; T245-L264 HydrophobicContact CG2-CB 3.96Å; T245-L264 HydrophobicContact CG2-CD1 4.22Å; S260-L264 WeakPolarHBondContact O-CB 3.46Å; S260-L264 PolarHBondContact O-N 3.29Å; W261-L264 HydrophobicContact CE3-CD2 4.18Å; W261-L264 HydrophobicContact CZ3-CD2 4.42Å; W261-L264 PolarHBondContact O-N 3.14Å; L264-K266 PolarHBondContact O-N 2.86Å; L264-R267 PolarHBondContact O-N 2.75Å; L264-I268 HydrophobicContact CD1-CD1 4.08Å; L264-I268 HydrophobicContact CD1-CG1 4.4Å; L264-I268 HydrophobicContact CG-CD1 4.14Å; L264-I268 WeakPolarHBondContact O-CG1 3.4Å; L264-I268 PolarHBondContact O-N 3.03Å
265	R	93.9	Very high	87.6	Confident	117 Å²	117	71.4 Å²	71.4	44%	0.442	34%	0.343	S	S	.	.	H	α-helix	trans	-58.9	-48	178.8	-174.8	178.3	-56.9	-74	-7.4	111.9	Y174 W261 I262 F263 R267 I268 E269	Y174-R265 HydrophobicContact CD2-CB 4.26Å; Y174-R265 HydrophobicContact CE2-CB 4.11Å; Y174-R265 PolarHBondContact OH-NH2 3.45Å; W261-R265 PolarHBondContact O-N 3.41Å; W261-R265 VanDerWaalsContact O-N 3.1Å; I262-R265 PolarHBondContact O-N 3.22Å; F263-R265 VanDerWaalsContact C-N 3.34Å; F263-R265 PolarHBondContact O-N 3.47Å; R265-R267 VanDerWaalsContact C-N 3.32Å; R265-R267 PolarHBondContact O-N 2.67Å; R265-I268 PolarHBondContact O-N 2.9Å; R265-E269 WeakPolarHBondContact O-CG 3.23Å; R265-E269 PolarHBondContact O-N 3.23Å
266	K	93.2	Very high	86.4	Confident	108 Å²	108	73.7 Å²	73.7	47%	0.47	34%	0.344	S	S	.	.	H	α-helix	trans	-59.7	-41.9	177.1	-71.4	174.8	179.4	173.4	0	111.8	I262 F263 L264 I268 E269 D270	I262-K266 HydrophobicContact CG2-CD 4.23Å; I262-K266 WeakPolarHBondContact O-CG 3.13Å; I262-K266 PolarHBondContact O-N 3.43Å; I262-K266 VanDerWaalsContact O-N 3.08Å; F263-K266 PolarHBondContact O-N 3.45Å; L264-K266 PolarHBondContact O-N 2.86Å; K266-I268 PolarHBondContact O-N 2.83Å; K266-E269 WeakPolarHBondContact O-CB 3.42Å; K266-E269 PolarHBondContact O-N 3.47Å; K266-D270 VanDerWaalsContact O-CG 3.22Å; K266-D270 PolarHBondContact O-N 2.67Å
267	R	93.3	Very high	85.2	Confident	56 Å²	56	71.1 Å²	71.1	21%	0.211	33%	0.334	C	S	.	.	H	α-helix	trans	-65.8	-35.4	178.2	-68.9	-59	83.2	80.4	-2.3	113.1	V241 F263 L264 R265 D270 L271	V241-R267 HydrophobicContact CB-CB 4.39Å; V241-R267 HydrophobicContact CG1-CB 3.78Å; V241-R267 HydrophobicContact CG2-CB 3.91Å; F263-R267 HydrophobicContact CD1-CG 3.87Å; F263-R267 HydrophobicContact CE1-CG 3.5Å; F263-R267 HydrophobicContact CE2-CG 4.42Å; F263-R267 HydrophobicContact CG-CG 4.45Å; F263-R267 HydrophobicContact CZ-CG 3.81Å; F263-R267 WeakPolarHBondContact O-CG 3.2Å; F263-R267 PolarHBondContact O-N 2.63Å; L264-R267 PolarHBondContact O-N 2.75Å; R265-R267 VanDerWaalsContact C-N 3.32Å; R265-R267 PolarHBondContact O-N 2.67Å; R267-D270 IonicContact CZ-OD2 2.92Å; R267-D270 IonicContact NE-OD2 2.72Å; R267-D270 PolarHBondContact NE-OD2 3.2Å; R267-D270 IonicContact NH2-OD2 3.43Å; R267-D270 PolarHBondContact NH2-OD2 3.43Å; R267-D270 PolarHBondContact O-N 2.82Å; R267-L271 PolarHBondContact O-N 3.45Å
268	I	91.8	Very high	83.6	Confident	6 Å²	6	75.8 Å²	75.8	3%	0.031	36%	0.359	C	S	.	.	H	α-helix	trans	-68.6	-40.1	173.4	-65.2	170	0	0	0	110.7	D170 L173 Y174 L177 V241 L264 R265 K266 D270 L271	D170-I268 HydrophobicContact CB-CG2 4.05Å; L173-I268 HydrophobicContact CB-CD1 4.39Å; Y174-I268 HydrophobicContact CD2-CD1 4.27Å; L177-I268 HydrophobicContact CD1-CD1 4.28Å; V241-I268 HydrophobicContact CG1-CG1 4.14Å; L264-I268 HydrophobicContact CD1-CD1 4.08Å; L264-I268 HydrophobicContact CD1-CG1 4.4Å; L264-I268 HydrophobicContact CG-CD1 4.14Å; L264-I268 WeakPolarHBondContact O-CG1 3.4Å; L264-I268 PolarHBondContact O-N 3.03Å; R265-I268 PolarHBondContact O-N 2.9Å; K266-I268 PolarHBondContact O-N 2.83Å; I268-D270 VanDerWaalsContact C-N 3.32Å; I268-D270 PolarHBondContact O-N 2.93Å; I268-L271 WeakPolarHBondContact O-CB 3.26Å; I268-L271 PolarHBondContact O-N 3.33Å
269	E	89.7	Confident	82.2	Confident	90 Å²	90	80.9 Å²	80.9	42%	0.421	38%	0.382	S	S	.	.	H	α-helix	trans	-62.3	-38.4	173.7	-70.9	167.7	-171.3	0	0	112	R265 K266 L271 R272 S273	R265-E269 WeakPolarHBondContact O-CG 3.23Å; R265-E269 PolarHBondContact O-N 3.23Å; K266-E269 WeakPolarHBondContact O-CB 3.42Å; K266-E269 PolarHBondContact O-N 3.47Å; E269-L271 VanDerWaalsContact C-N 3.3Å; E269-L271 PolarHBondContact O-N 3.02Å; E269-R272 WeakPolarHBondContact O-CB 3.28Å; E269-R272 PolarHBondContact O-N 2.74Å; E269-R272 VanDerWaalsContact O-N 3.12Å; E269-S273 PolarHBondContact O-N 2.96Å
270	D	88.8	Confident	80.5	Confident	65 Å²	65	85 Å²	85	35%	0.348	40%	0.398	S	S	.	.	H	α-helix	trans	-61.6	-35.6	174.5	-67.8	-26.6	0	0	0	112.2	K266 R267 I268 R272 S273 M274	K266-D270 VanDerWaalsContact O-CG 3.22Å; K266-D270 PolarHBondContact O-N 2.67Å; R267-D270 IonicContact CZ-OD2 2.92Å; R267-D270 IonicContact NE-OD2 2.72Å; R267-D270 PolarHBondContact NE-OD2 3.2Å; R267-D270 IonicContact NH2-OD2 3.43Å; R267-D270 PolarHBondContact NH2-OD2 3.43Å; R267-D270 PolarHBondContact O-N 2.82Å; I268-D270 VanDerWaalsContact C-N 3.32Å; I268-D270 PolarHBondContact O-N 2.93Å; D270-R272 VanDerWaalsContact C-N 3.25Å; D270-R272 PolarHBondContact O-N 3.14Å; D270-S273 PolarHBondContact O-N 3.4Å; D270-S273 PolarHBondContact O-OG 2.89Å; D270-M274 WeakPolarHBondContact O-CG 3.18Å; D270-M274 PolarHBondContact O-N 3.17Å
271	L	85.5	Confident	79.1	Confident	38 Å²	38	87.2 Å²	87.2	20%	0.199	42%	0.417	C	S	.	.	H	α-helix	trans	-62.6	-33.6	175.6	-66.7	-178.2	0	0	0	112.2	V238 V241 R267 I268 E269 K275	V238-L271 HydrophobicContact CG2-CD1 4.49Å; V241-L271 HydrophobicContact CG2-CD1 3.59Å; V241-L271 HydrophobicContact CG2-CD2 4.08Å; V241-L271 HydrophobicContact CG2-CG 3.79Å; R267-L271 PolarHBondContact O-N 3.45Å; I268-L271 WeakPolarHBondContact O-CB 3.26Å; I268-L271 PolarHBondContact O-N 3.33Å; E269-L271 VanDerWaalsContact C-N 3.3Å; E269-L271 PolarHBondContact O-N 3.02Å; L271-K275 PolarHBondContact O-N 3.37Å
272	R	78	Confident	77.8	Confident	98 Å²	98	88.3 Å²	88.3	37%	0.37	43%	0.433	S	S	.	.	H	α-helix	trans	-70.2	-43.7	175.6	-89.1	-175.7	-84.9	161.4	-15.3	112	D170 E269 D270 M274 K275 Q276	D170-R272 WeakPolarHBondContact OD1-CD 3.29Å; D170-R272 IonicContact OD1-CZ 2.61Å; D170-R272 IonicContact OD1-NE 2.74Å; D170-R272 PolarHBondContact OD1-NE 2.91Å; D170-R272 IonicContact OD1-NH2 3.11Å; D170-R272 PolarHBondContact OD1-NH2 3.41Å; D170-R272 VanDerWaalsContact OD2-CD 3.27Å; D170-R272 WeakPolarHBondContact OD2-CD 3.43Å; D170-R272 IonicContact OD2-CZ 3.04Å; D170-R272 IonicContact OD2-NE 3.19Å; D170-R272 PolarHBondContact OD2-NE 3.05Å; D170-R272 IonicContact OD2-NH1 3.42Å; D170-R272 PolarHBondContact OD2-NH1 2.96Å; D170-R272 IonicContact OD2-NH2 2.69Å; D170-R272 PolarHBondContact OD2-NH2 2.76Å; E269-R272 WeakPolarHBondContact O-CB 3.28Å; E269-R272 PolarHBondContact O-N 2.74Å; E269-R272 VanDerWaalsContact O-N 3.12Å; D270-R272 VanDerWaalsContact C-N 3.25Å; D270-R272 PolarHBondContact O-N 3.14Å; R272-M274 VanDerWaalsContact C-N 3.28Å; R272-M274 PolarHBondContact O-N 2.91Å; R272-K275 PolarHBondContact O-N 3.08Å; R272-Q276 PolarHBondContact O-N 3.34Å
273	S	75.6	Confident	76.5	Confident	58 Å²	58	88.1 Å²	88.1	41%	0.406	44%	0.438	S	S	.	.	H	α-helix	trans	-64.7	-36.3	178.8	71.4	0	0	0	0	111.3	E269 D270 K275 Q276 M277	E269-S273 PolarHBondContact O-N 2.96Å; D270-S273 PolarHBondContact O-N 3.4Å; D270-S273 PolarHBondContact O-OG 2.89Å; S273-K275 VanDerWaalsContact C-N 3.32Å; S273-K275 PolarHBondContact O-N 3.14Å; S273-Q276 WeakPolarHBondContact O-CB 3.04Å; S273-Q276 PolarHBondContact O-N 2.89Å; S273-M277 PolarHBondContact O-N 3.16Å; S273-M277 VanDerWaalsContact O-N 3.16Å
274	M	70.3	Confident	75.5	Confident	110 Å²	110	89 Å²	89	54%	0.542	45%	0.448	S	S	.	.	H	α-helix	trans	-61	-37.4	173.8	-76.1	179.1	53.5	0	0	113.3	D270 R272 Q276 M277	D270-M274 WeakPolarHBondContact O-CG 3.18Å; D270-M274 PolarHBondContact O-N 3.17Å; R272-M274 VanDerWaalsContact C-N 3.28Å; R272-M274 PolarHBondContact O-N 2.91Å; M274-Q276 VanDerWaalsContact C-N 3.27Å; M274-Q276 PolarHBondContact O-N 3.25Å; M274-M277 HydrophobicContact CB-CE 4.23Å; M274-M277 HydrophobicContact CG-CE 3.93Å; M274-M277 PolarHBondContact O-N 3.48Å
275	K	66.8	Low	74.5	Confident	178 Å²	178	95.7 Å²	95.7	77%	0.774	48%	0.481	S	S	*	.	H	α-helix	trans	-67.5	-28.9	175.2	-171.5	-179	176.6	-172.1	0	112.3	L271 R272 S273	L271-K275 PolarHBondContact O-N 3.37Å; R272-K275 PolarHBondContact O-N 3.08Å; S273-K275 VanDerWaalsContact C-N 3.32Å; S273-K275 PolarHBondContact O-N 3.14Å
276	Q	60.6	Low	73.8	Confident	155 Å²	155	96 Å²	96	72%	0.724	49%	0.491	S	S	*	.	H	α-helix	trans	-81.4	-18	179.4	-66.6	177.1	3.8	0	0	113.1	R272 S273 M274 N278	R272-Q276 PolarHBondContact O-N 3.34Å; S273-Q276 WeakPolarHBondContact O-CB 3.04Å; S273-Q276 PolarHBondContact O-N 2.89Å; M274-Q276 VanDerWaalsContact C-N 3.27Å; M274-Q276 PolarHBondContact O-N 3.25Å; Q276-N278 PolarHBondContact O-N 3.06Å
277	M	60	Low	73.1	Confident	132 Å²	132	93.2 Å²	93.2	65%	0.65	49%	0.488	S	S	*	.	S	Bend	trans	-63	102.6	168.1	-69	-164.6	-72.7	0	0	108.7	S273 M274 L279	S273-M277 PolarHBondContact O-N 3.16Å; S273-M277 VanDerWaalsContact O-N 3.16Å; M274-M277 HydrophobicContact CB-CE 4.23Å; M274-M277 HydrophobicContact CG-CE 3.93Å; M274-M277 PolarHBondContact O-N 3.48Å; M277-L279 PolarHBondContact O-N 3.44Å
278	N	54.9	Low	72.4	Confident	115 Å²	115	95.4 Å²	95.4	62%	0.615	50%	0.504	S	S	*	.			trans	-54.2	110.2	173.3	-91.2	-43.4	0	0	0	108.1	Q276 K280 A281 A282	Q276-N278 PolarHBondContact O-N 3.06Å; N278-K280 PolarHBondContact O-N 3.31Å; N278-A281 HydrophobicContact CB-CB 4.31Å; N278-A281 WeakPolarHBondContact O-CA 3.26Å; N278-A281 WeakPolarHBondContact O-CB 3.43Å; N278-A281 PolarHBondContact O-N 3.12Å; N278-A282 PolarHBondContact O-N 2.92Å
279	L	61	Low	71.9	Confident	151 Å²	151	97.1 Å²	97.1	79%	0.791	52%	0.523	S	S	*	.	H	α-helix	trans	-49	-27.5	169.9	-93.7	144.6	0	0	0	111.4	M277 A282 S283	M277-L279 PolarHBondContact O-N 3.44Å; L279-A282 PolarHBondContact O-N 3.43Å; L279-S283 VanDerWaalsContact O-CB 3.28Å; L279-S283 WeakPolarHBondContact O-CB 3.3Å; L279-S283 PolarHBondContact O-N 2.72Å; L279-S283 PolarHBondContact O-OG 2.82Å; L279-S283 VanDerWaalsContact O-OG 3.13Å
280	K	57.8	Low	71.4	Confident	168 Å²	168	97.7 Å²	97.7	73%	0.73	53%	0.533	S	S	*	.	H	α-helix	trans	-62.9	-34.9	172.1	-66.5	-174.6	178.5	-179.4	0	114.3	N278 S283 S284	N278-K280 PolarHBondContact O-N 3.31Å; K280-S283 WeakPolarHBondContact CA-OG 3.47Å; K280-S283 PolarHBondContact O-OG 3.42Å; K280-S284 VanDerWaalsContact O-CB 3.25Å; K280-S284 WeakPolarHBondContact O-CB 3.38Å; K280-S284 PolarHBondContact O-N 3.48Å; K280-S284 PolarHBondContact O-OG 3.21Å; K280-S284 VanDerWaalsContact O-OG 3.08Å
281	A	63.9	Low	71	Confident	48 Å²	48	99.7 Å²	99.7	40%	0.397	54%	0.543	S	S	.	.	H	α-helix	trans	-73.9	-43.4	175.9	0	0	0	0	0	110.9	N278 S283 S284 M285	N278-A281 HydrophobicContact CB-CB 4.31Å; N278-A281 WeakPolarHBondContact O-CA 3.26Å; N278-A281 WeakPolarHBondContact O-CB 3.43Å; N278-A281 PolarHBondContact O-N 3.12Å; A281-S283 PolarHBondContact O-N 3.47Å; A281-S284 PolarHBondContact O-N 3.02Å; A281-S284 PolarHBondContact O-OG 3.1Å; A281-S284 VanDerWaalsContact O-OG 3.11Å; A281-M285 WeakPolarHBondContact O-CB 3.48Å; A281-M285 WeakPolarHBondContact O-CG 3.47Å; A281-M285 PolarHBondContact O-N 2.96Å
282	A	66.2	Low	70.7	Confident	54 Å²	54	100.5 Å²	100.5	45%	0.446	56%	0.555	S	S	.	*	H	α-helix	trans	-63.5	-41.7	174	0	0	0	0	0	111.7	N278 L279 L286	N278-A282 PolarHBondContact O-N 2.92Å; L279-A282 PolarHBondContact O-N 3.43Å; A282-L286 WeakPolarHBondContact O-CB 3.48Å; A282-L286 WeakPolarHBondContact O-CG 3.41Å; A282-L286 PolarHBondContact O-N 3.44Å
283	S	66.6	Low	70.7	Confident	68 Å²	68	102.9 Å²	102.9	48%	0.476	57%	0.568	S	S	.	*	H	α-helix	trans	-70.6	-38.1	179.1	70.1	0	0	0	0	112.7	L279 K280 A281 A287	L279-S283 VanDerWaalsContact O-CB 3.28Å; L279-S283 WeakPolarHBondContact O-CB 3.3Å; L279-S283 PolarHBondContact O-N 2.72Å; L279-S283 PolarHBondContact O-OG 2.82Å; L279-S283 VanDerWaalsContact O-OG 3.13Å; K280-S283 WeakPolarHBondContact CA-OG 3.47Å; K280-S283 PolarHBondContact O-OG 3.42Å; A281-S283 PolarHBondContact O-N 3.47Å; S283-A287 WeakPolarHBondContact O-CB 3.4Å; S283-A287 PolarHBondContact O-N 3.1Å
284	S	72.5	Confident	70.9	Confident	53 Å²	53	101.4 Å²	101.4	37%	0.371	56%	0.562	S	S	.	*	H	α-helix	trans	-69.3	-38.4	175.4	68.8	0	0	0	0	111.8	K280 A281 A287 N288	K280-S284 VanDerWaalsContact O-CB 3.25Å; K280-S284 WeakPolarHBondContact O-CB 3.38Å; K280-S284 PolarHBondContact O-N 3.48Å; K280-S284 PolarHBondContact O-OG 3.21Å; K280-S284 VanDerWaalsContact O-OG 3.08Å; A281-S284 PolarHBondContact O-N 3.02Å; A281-S284 PolarHBondContact O-OG 3.1Å; A281-S284 VanDerWaalsContact O-OG 3.11Å; S284-A287 PolarHBondContact O-N 3.04Å; S284-N288 WeakPolarHBondContact O-CB 3.48Å; S284-N288 PolarHBondContact O-N 3.33Å; S284-N288 PolarHBondContact O-ND2 3.46Å
285	M	75	Confident	71.2	Confident	141 Å²	141	101.1 Å²	101.1	70%	0.695	56%	0.563	S	S	*	*	H	α-helix	trans	-64.4	-43.9	174.2	-72.1	177.3	76.5	0	0	111.8	A281 G289	A281-M285 WeakPolarHBondContact O-CB 3.48Å; A281-M285 WeakPolarHBondContact O-CG 3.47Å; A281-M285 PolarHBondContact O-N 2.96Å; M285-G289 PolarHBondContact O-N 2.99Å
286	L	77.4	Confident	71.8	Confident	124 Å²	124	97 Å²	97	65%	0.649	55%	0.552	S	S	*	*	H	α-helix	trans	-65.9	-43.5	175.2	-76.4	169.6	0	0	0	111.9	A282 G289 V290	A282-L286 WeakPolarHBondContact O-CB 3.48Å; A282-L286 WeakPolarHBondContact O-CG 3.41Å; A282-L286 PolarHBondContact O-N 3.44Å; L286-G289 PolarHBondContact O-N 3.25Å; L286-V290 WeakPolarHBondContact O-CB 3.42Å; L286-V290 VanDerWaalsContact O-CG2 3.31Å; L286-V290 WeakPolarHBondContact O-CG2 3.44Å; L286-V290 PolarHBondContact O-N 2.84Å
287	A	78.9	Confident	72.7	Confident	49 Å²	49	91.8 Å²	91.8	41%	0.405	53%	0.531	S	S	.	.	H	α-helix	trans	-61.9	-45.9	176.7	0	0	0	0	0	111.3	S283 S284 G289 V290 L291	S283-A287 WeakPolarHBondContact O-CB 3.4Å; S283-A287 PolarHBondContact O-N 3.1Å; S284-A287 PolarHBondContact O-N 3.04Å; A287-G289 VanDerWaalsContact C-N 3.34Å; A287-G289 PolarHBondContact O-N 3.27Å; A287-V290 PolarHBondContact O-N 3.48Å; A287-L291 WeakPolarHBondContact O-CB 3.27Å; A287-L291 VanDerWaalsContact O-CG 3.26Å; A287-L291 WeakPolarHBondContact O-CG 3.5Å; A287-L291 PolarHBondContact O-N 3.39Å
288	N	79.5	Confident	73.5	Confident	102 Å²	102	88 Å²	88	55%	0.545	52%	0.517	S	S	.	.	H	α-helix	trans	-65.2	-38.1	176.3	-69.9	-17.7	0	0	0	111.6	S284 L291 A292	S284-N288 WeakPolarHBondContact O-CB 3.48Å; S284-N288 PolarHBondContact O-N 3.33Å; S284-N288 PolarHBondContact O-ND2 3.46Å; N288-L291 PolarHBondContact O-N 2.95Å; N288-A292 WeakPolarHBondContact O-CB 3.49Å; N288-A292 PolarHBondContact O-N 2.83Å
289	G	80.1	Confident	74.7	Confident	42 Å²	42	87.7 Å²	87.7	43%	0.433	52%	0.515	S	S	.	.	H	α-helix	trans	-63.6	-44	175.2	0	0	0	0	0	112.5	M285 L286 A287 A292 F293	M285-G289 PolarHBondContact O-N 2.99Å; L286-G289 PolarHBondContact O-N 3.25Å; A287-G289 VanDerWaalsContact C-N 3.34Å; A287-G289 PolarHBondContact O-N 3.27Å; G289-A292 PolarHBondContact O-N 3.1Å; G289-F293 WeakPolarHBondContact O-CB 3.24Å; G289-F293 PolarHBondContact O-N 2.81Å
290	V	81	Confident	75.7	Confident	102 Å²	102	86.1 Å²	86.1	62%	0.618	51%	0.512	S	S	*	.	H	α-helix	trans	-67.4	-41.5	176.1	171.4	0	0	0	0	111.3	L286 A287 F293 G294	L286-V290 WeakPolarHBondContact O-CB 3.42Å; L286-V290 VanDerWaalsContact O-CG2 3.31Å; L286-V290 WeakPolarHBondContact O-CG2 3.44Å; L286-V290 PolarHBondContact O-N 2.84Å; A287-V290 PolarHBondContact O-N 3.48Å; V290-F293 PolarHBondContact O-N 3.15Å; V290-G294 PolarHBondContact O-N 3.04Å
291	L	79.9	Confident	76.6	Confident	108 Å²	108	83.1 Å²	83.1	57%	0.565	50%	0.503	S	S	*	.	H	α-helix	trans	-66	-39.3	175.4	-71.7	174.4	0	0	0	112	A287 N288 G294 N295	A287-L291 WeakPolarHBondContact O-CB 3.27Å; A287-L291 VanDerWaalsContact O-CG 3.26Å; A287-L291 WeakPolarHBondContact O-CG 3.5Å; A287-L291 PolarHBondContact O-N 3.39Å; N288-L291 PolarHBondContact O-N 2.95Å; L291-G294 PolarHBondContact O-N 3.28Å; L291-N295 WeakPolarHBondContact O-CB 3.41Å; L291-N295 PolarHBondContact O-N 2.91Å
292	A	79.7	Confident	76.9	Confident	54 Å²	54	83.9 Å²	83.9	45%	0.446	52%	0.516	S	S	.	.	H	α-helix	trans	-64	-45.9	175.2	0	0	0	0	0	111	N288 G289 G294 N295 V296	N288-A292 WeakPolarHBondContact O-CB 3.49Å; N288-A292 PolarHBondContact O-N 2.83Å; G289-A292 PolarHBondContact O-N 3.1Å; A292-G294 VanDerWaalsContact C-N 3.32Å; A292-G294 PolarHBondContact O-N 3.19Å; A292-N295 PolarHBondContact O-N 3.4Å; A292-V296 WeakPolarHBondContact O-CB 3.39Å; A292-V296 VanDerWaalsContact O-CG2 3.27Å; A292-V296 WeakPolarHBondContact O-CG2 3.4Å; A292-V296 PolarHBondContact O-N 3.35Å
293	F	77.6	Confident	77	Confident	148 Å²	148	91 Å²	91	65%	0.649	53%	0.531	S	S	*	.	H	α-helix	trans	-61.8	-42.1	174.1	-176	-96.2	0	0	0	111.7	G289 V290 V296 T297	G289-F293 WeakPolarHBondContact O-CB 3.24Å; G289-F293 PolarHBondContact O-N 2.81Å; V290-F293 PolarHBondContact O-N 3.15Å; F293-V296 PolarHBondContact O-N 2.93Å; F293-T297 VanDerWaalsContact O-CB 3.25Å; F293-T297 WeakPolarHBondContact O-CB 3.48Å; F293-T297 PolarHBondContact O-N 3.17Å; F293-T297 PolarHBondContact O-OG1 3.08Å
294	G	78.8	Confident	76.8	Confident	27 Å²	27	93.2 Å²	93.2	28%	0.278	54%	0.538	S	S	.	.	H	α-helix	trans	-60.2	-49.1	175.6	0	0	0	0	0	112.1	V290 L291 A292 T297 C298	V290-G294 PolarHBondContact O-N 3.04Å; L291-G294 PolarHBondContact O-N 3.28Å; A292-G294 VanDerWaalsContact C-N 3.32Å; A292-G294 PolarHBondContact O-N 3.19Å; G294-T297 CarbonylContact O-C 3.59Å; G294-T297 PolarHBondContact O-N 3.49Å; G294-C298 WeakPolarHBondContact O-CB 3.35Å; G294-C298 PolarHBondContact O-N 2.72Å; G294-C298 PolarHBondContact O-SG 3.33Å
295	N	76.7	Confident	75.9	Confident	104 Å²	104	102.2 Å²	102.2	56%	0.556	56%	0.563	S	S	*	*	H	α-helix	trans	-65.4	-41.2	179.1	-77.1	-19.5	0	0	0	112.4	L291 A292 T297 C298 N299	L291-N295 WeakPolarHBondContact O-CB 3.41Å; L291-N295 PolarHBondContact O-N 2.91Å; A292-N295 PolarHBondContact O-N 3.4Å; N295-T297 VanDerWaalsContact C-N 3.32Å; N295-C298 PolarHBondContact O-N 3.4Å; N295-N299 VanDerWaalsContact O-CB 3.31Å; N295-N299 WeakPolarHBondContact O-CB 3.4Å; N295-N299 VanDerWaalsContact O-CG 3.25Å; N295-N299 PolarHBondContact O-N 2.96Å
296	V	80.7	Confident	74.9	Confident	91 Å²	91	102.4 Å²	102.4	55%	0.552	57%	0.567	S	S	*	*	H	α-helix	trans	-61.8	-44.2	173.6	171.5	0	0	0	0	110.1	A292 F293 N299 V300	A292-V296 WeakPolarHBondContact O-CB 3.39Å; A292-V296 VanDerWaalsContact O-CG2 3.27Å; A292-V296 WeakPolarHBondContact O-CG2 3.4Å; A292-V296 PolarHBondContact O-N 3.35Å; F293-V296 PolarHBondContact O-N 2.93Å; V296-N299 PolarHBondContact O-N 3.06Å; V296-V300 WeakPolarHBondContact O-CB 3.32Å; V296-V300 VanDerWaalsContact O-CG2 3.24Å; V296-V300 WeakPolarHBondContact O-CG2 3.46Å; V296-V300 PolarHBondContact O-N 3.41Å
297	T	79.1	Confident	73	Confident	47 Å²	47	106.6 Å²	106.6	29%	0.288	60%	0.598	S	S	.	*	H	α-helix	trans	-65.6	-42.5	178.4	-57.5	0	0	0	0	111.8	F293 G294 N295 V300 L301	F293-T297 VanDerWaalsContact O-CB 3.25Å; F293-T297 WeakPolarHBondContact O-CB 3.48Å; F293-T297 PolarHBondContact O-N 3.17Å; F293-T297 PolarHBondContact O-OG1 3.08Å; G294-T297 CarbonylContact O-C 3.59Å; G294-T297 PolarHBondContact O-N 3.49Å; N295-T297 VanDerWaalsContact C-N 3.32Å; T297-V300 PolarHBondContact O-N 2.8Å; T297-L301 HydrophobicContact CG2-CD1 3.69Å; T297-L301 HydrophobicContact CG2-CG 4.32Å; T297-L301 WeakPolarHBondContact O-CB 3.34Å; T297-L301 VanDerWaalsContact O-CG 3.25Å; T297-L301 WeakPolarHBondContact O-CG 3.46Å; T297-L301 PolarHBondContact O-N 3.43Å
298	C	77.2	Confident	72.7	Confident	52 Å²	52	109.5 Å²	109.5	35%	0.351	61%	0.608	S	S	.	*	H	α-helix	trans	-66.2	-37.7	176.6	-71.5	0	0	0	0	112.5	G294 N295 L301 G302 W303	G294-C298 WeakPolarHBondContact O-CB 3.35Å; G294-C298 PolarHBondContact O-N 2.72Å; G294-C298 PolarHBondContact O-SG 3.33Å; N295-C298 PolarHBondContact O-N 3.4Å; C298-L301 PolarHBondContact O-N 3.42Å; C298-G302 PolarHBondContact O-N 3.28Å; C298-W303 PolarHBondContact O-N 3.42Å; C298-W303 VanDerWaalsContact O-N 3.13Å
299	N	80	Confident	72.3	Confident	108 Å²	108	109.9 Å²	109.9	58%	0.578	61%	0.611	S	S	*	*	H	α-helix	trans	-66	-40	173.7	-77	-13.9	0	0	0	111.5	N295 V296 G302	N295-N299 VanDerWaalsContact O-CB 3.31Å; N295-N299 WeakPolarHBondContact O-CB 3.4Å; N295-N299 VanDerWaalsContact O-CG 3.25Å; N295-N299 PolarHBondContact O-N 2.96Å; V296-N299 PolarHBondContact O-N 3.06Å; N299-G302 PolarHBondContact O-N 3.19Å
300	V	80.6	Confident	71.9	Confident	119 Å²	119	113.7 Å²	113.7	72%	0.721	62%	0.621	S	S	*	*	H	α-helix	trans	-68.7	-36.8	176	170.1	0	0	0	0	111.9	V296 T297 G302	V296-V300 WeakPolarHBondContact O-CB 3.32Å; V296-V300 VanDerWaalsContact O-CG2 3.24Å; V296-V300 WeakPolarHBondContact O-CG2 3.46Å; V296-V300 PolarHBondContact O-N 3.41Å; T297-V300 PolarHBondContact O-N 2.8Å; V300-G302 VanDerWaalsContact C-N 3.27Å; V300-G302 PolarHBondContact O-N 3.47Å
301	L	76.2	Confident	71.3	Confident	104 Å²	104	114.4 Å²	114.4	55%	0.545	62%	0.622	S	S	.	*	T	Hydrogen-bonded Turn	trans	-82.4	2	179.9	-68.3	173	0	0	0	113.9	T297 C298 W303	T297-L301 HydrophobicContact CG2-CD1 3.69Å; T297-L301 HydrophobicContact CG2-CG 4.32Å; T297-L301 WeakPolarHBondContact O-CB 3.34Å; T297-L301 VanDerWaalsContact O-CG 3.25Å; T297-L301 WeakPolarHBondContact O-CG 3.46Å; T297-L301 PolarHBondContact O-N 3.43Å; C298-L301 PolarHBondContact O-N 3.42Å; L301-W303 HydrophobicContact CD1-CE3 4.37Å; L301-W303 HydrophobicContact CD1-CZ3 4.39Å; L301-W303 PolarHBondContact O-N 3.03Å
302	G	70.4	Confident	70.8	Confident	64 Å²	64	114.8 Å²	114.8	66%	0.66	63%	0.625	S	S	*	*	T	Hydrogen-bonded Turn	trans	64.9	20.6	177.7	0	0	0	0	0	114.2	C298 N299 V300 N304	C298-G302 PolarHBondContact O-N 3.28Å; N299-G302 PolarHBondContact O-N 3.19Å; V300-G302 VanDerWaalsContact C-N 3.27Å; V300-G302 PolarHBondContact O-N 3.47Å; G302-N304 VanDerWaalsContact C-N 3.28Å; G302-N304 PolarHBondContact O-N 3.5Å
303	W	68.8	Low	70.2	Confident	205 Å²	205	118.8 Å²	118.8	78%	0.777	64%	0.637	S	S	*	*			trans	-84.9	10	-175.4	-95.2	-13.9	0	0	0	114.8	C298 L301 R305	C298-W303 PolarHBondContact O-N 3.42Å; C298-W303 VanDerWaalsContact O-N 3.13Å; L301-W303 HydrophobicContact CD1-CE3 4.37Å; L301-W303 HydrophobicContact CD1-CZ3 4.39Å; L301-W303 PolarHBondContact O-N 3.03Å; W303-R305 PolarHBondContact O-N 3.45Å
304	N	62.6	Low	69.7	Low	114 Å²	114	116.7 Å²	116.7	61%	0.61	64%	0.636	S	S	*	*			trans	-90.3	85.5	178.9	-158.8	9.9	0	0	0	111.6	G302	G302-N304 VanDerWaalsContact C-N 3.28Å; G302-N304 PolarHBondContact O-N 3.5Å
305	R	53.8	Low	69	Low	241 Å²	241	123.6 Å²	123.6	91%	0.909	66%	0.664	S	S	*	*			trans	-98.8	111.8	166.6	-103.7	-179.2	164.4	161.4	-3.8	109	W303 T307	W303-R305 PolarHBondContact O-N 3.45Å; R305-T307 PolarHBondContact O-N 3.02Å
306	N	53.4	Low	68.3	Low	146 Å²	146	125.3 Å²	125.3	78%	0.781	67%	0.673	S	S	*	*			trans	-54.8	110.7	172.1	-66.1	-27.5	0	0	0	112
307	T	37.3	Very low	67.2	Low	212 Å²	212	128.4 Å²	128.4	100%	1.301	68%	0.684	S	S	*	*			trans	-158.5	0	138.4	44.5	0	0	0	0	108.4	R305	R305-T307 PolarHBondContact O-N 3.02Å

Retrieved 307 of 307 residues in 180.9 ms (Link to these results)

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