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Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment.

AlphaFold DB (A4FV68), UniProt , Accession Q16537, Species HUMAN (Homo sapiens, Human), Gene PPP2R5E, Length 467 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	39.8	Very low	40.3	Very low	250 Å²	250	133.8 Å²	133.8	100%	1.232	85%	0.849	S	S	*	*				0	120.8	0	-66.3	-179.7	100.2	0	0	106.6
2	S	36.6	Very low	40.3	Very low	127 Å²	127	134.1 Å²	134.1	89%	0.888	84%	0.84	S	S	*	*			trans	-76.9	140.1	-163.5	-61.5	0	0	0	0	114.5
3	S	40.2	Very low	40.1	Very low	124 Å²	124	139.3 Å²	139.3	87%	0.867	84%	0.843	S	S	*	*			trans	-167.2	135.2	140.2	42.1	0	0	0	0	110.1
4	A	41.1	Very low	40	Very low	88 Å²	88	138.9 Å²	138.9	73%	0.727	84%	0.84	S	S	*	*			trans	-73.7	168.8	-161	0	0	0	0	0	116
5	P	39	Very low	40	Very low	128 Å²	128	140.5 Å²	140.5	83%	0.831	84%	0.843	S	S	*	*			trans	-87	129.1	171.9	33.7	-27.8	0	0	0	111.1
6	T	44.1	Very low	39.9	Very low	140 Å²	140	135.2 Å²	135.2	86%	0.859	83%	0.825	S	S	*	*			trans	-105.2	116.2	171.6	32	0	0	0	0	110.7
7	T	40	Very low	39.7	Very low	133 Å²	133	139.9 Å²	139.9	82%	0.816	83%	0.832	S	S	*	*	P	Polyproline II helix	trans	-63.4	140.9	165.3	39.3	0	0	0	0	111.7
8	P	46.3	Very low	39.7	Very low	120 Å²	120	138.4 Å²	138.4	78%	0.779	83%	0.83	S	S	*	*	P	Polyproline II helix	trans	-78.1	156.8	171.9	31.7	-30.6	0	0	0	111.8
9	P	38.5	Very low	39.5	Very low	112 Å²	112	144.4 Å²	144.4	73%	0.727	84%	0.836	S	S	*	*	P	Polyproline II helix	trans	-88.1	151.9	-161.8	32	-25.3	0	0	0	113.2	V11	P9-V11 PolarHBondContact O-N 3.01Å
10	S	34.8	Very low	39.6	Very low	109 Å²	109	146.6 Å²	146.6	76%	0.762	84%	0.836	S	S	*	*	P	Polyproline II helix	trans	-59.4	122.3	166.8	48.7	0	0	0	0	110.7	D12	S10-D12 PolarHBondContact O-N 3.43Å
11	V	43.5	Very low	39.5	Very low	141 Å²	141	144.1 Å²	144.1	86%	0.855	83%	0.827	S	S	*	*			trans	-86.3	110	174.5	-177.2	0	0	0	0	108.5	P9	P9-V11 PolarHBondContact O-N 3.01Å
12	D	39.7	Very low	39.2	Very low	137 Å²	137	139.2 Å²	139.2	73%	0.733	81%	0.811	S	S	*	*			trans	-55.8	135.9	170.5	-76.9	-51.8	0	0	0	111.7	S10 V14	S10-D12 PolarHBondContact O-N 3.43Å; D12-V14 PolarHBondContact O-N 3.3Å
13	K	37.7	Very low	39.3	Very low	202 Å²	202	143.6 Å²	143.6	88%	0.878	81%	0.808	S	S	*	*			trans	-58.8	116.1	171	-73.6	178.3	172.8	-177.1	0	110
14	V	38.5	Very low	39.2	Very low	134 Å²	134	147.1 Å²	147.1	81%	0.812	81%	0.808	S	S	*	*			trans	-116.3	86.6	164.1	-174.7	0	0	0	0	107.5	D12 G16	D12-V14 PolarHBondContact O-N 3.3Å; V14-G16 PolarHBondContact O-N 2.99Å
15	D	41	Very low	39	Very low	163 Å²	163	147 Å²	147	87%	0.872	81%	0.807	S	S	*	*			trans	-79.9	107.6	165.6	-92.4	-35.7	0	0	0	109.2
16	G	37.8	Very low	38.8	Very low	55 Å²	55	150.9 Å²	150.9	57%	0.567	81%	0.805	S	S	*	*			trans	-102.4	125	169.6	0	0	0	0	0	110.5	V14	V14-G16 PolarHBondContact O-N 2.99Å
17	F	36	Very low	38.5	Very low	215 Å²	215	153.7 Å²	153.7	94%	0.943	81%	0.809	S	S	*	*			trans	80.1	79.3	161.7	-60.1	-86.9	0	0	0	118.8
18	S	39.9	Very low	38.8	Very low	113 Å²	113	155.6 Å²	155.6	79%	0.79	81%	0.806	S	S	*	*				-142.2	87.6	125.9	-165.9	0	0	0	0	110.1	K20	S18-K20 PolarHBondContact O-N 3.33Å
19	R	35.2	Very low	38.8	Very low	252 Å²	252	160.9 Å²	160.9	95%	0.951	81%	0.81	S	S	*	*			trans	-87.6	85.7	162.5	-80.8	-174.2	-175.9	174	2.6	107.9
20	K	41.7	Very low	39.4	Very low	189 Å²	189	157.4 Å²	157.4	82%	0.822	79%	0.789	S	S	*	*			trans	-125.1	99.1	155.9	-80.1	-174.3	179.9	176	0	109.3	S18	S18-K20 PolarHBondContact O-N 3.33Å
21	S	38.2	Very low	40.4	Very low	95 Å²	95	156.8 Å²	156.8	66%	0.664	77%	0.773	S	S	*	*			trans	53.3	90.1	151.9	-173.1	0	0	0	0	118	R23	S21-R23 VanDerWaalsContact C-N 3.27Å; S21-R23 PolarHBondContact O-N 2.88Å
22	V	34.1	Very low	40.6	Very low	147 Å²	147	152.9 Å²	152.9	89%	0.891	75%	0.752	S	S	*	*			trans	-57.8	89.2	153.1	-179.8	0	0	0	0	108.9
23	R	38.6	Very low	41.4	Very low	218 Å²	218	146.6 Å²	146.6	82%	0.823	72%	0.719	S	S	*	*			trans	-88.5	110.6	157.5	-81.8	-176.8	176.6	-179.3	0.1	106.1	S21 A25	S21-R23 VanDerWaalsContact C-N 3.27Å; S21-R23 PolarHBondContact O-N 2.88Å; R23-A25 PolarHBondContact O-N 2.68Å
24	K	36.7	Very low	42.1	Very low	198 Å²	198	140.5 Å²	140.5	86%	0.861	70%	0.702	S	S	*	*			trans	-47.8	107.9	165.9	-80.6	178.3	171.9	178.5	0	108.6	R26	K24-R26 PolarHBondContact O-N 2.98Å; K24-R26 VanDerWaalsContact O-N 3.12Å
25	A	38.8	Very low	43.1	Very low	87 Å²	87	137.7 Å²	137.7	72%	0.719	68%	0.68	S	S	*	*			trans	-59.2	114.6	168.2	0	0	0	0	0	107.5	R23 Q27	R23-A25 PolarHBondContact O-N 2.68Å; A25-Q27 PolarHBondContact O-N 2.86Å
26	R	34.4	Very low	43.9	Very low	208 Å²	208	131.7 Å²	131.7	79%	0.785	65%	0.647	S	S	*	*			trans	-62.9	123.4	164.8	-86.9	169.5	74	174.5	3.3	105.7	K24 K28	K24-R26 PolarHBondContact O-N 2.98Å; K24-R26 VanDerWaalsContact O-N 3.12Å; R26-K28 HydrophobicContact CB-CG 4.31Å; R26-K28 WeakPolarHBondContact O-CG 3.41Å; R26-K28 PolarHBondContact O-N 3.27Å
27	Q	37.9	Very low	44.2	Very low	199 Å²	199	140 Å²	140	93%	0.93	66%	0.661	S	S	*	*			trans	-50.3	104.5	160	-81.4	177.6	-32.1	0	0	107.6	A25	A25-Q27 PolarHBondContact O-N 2.86Å
28	K	46.2	Very low	44.6	Very low	173 Å²	173	134.8 Å²	134.8	75%	0.752	65%	0.651	S	S	*	*	P	Polyproline II helix	trans	-101.3	137.3	179.9	-80.8	177.4	-178.5	176.9	0	108.1	R26 S30	R26-K28 HydrophobicContact CB-CG 4.31Å; R26-K28 WeakPolarHBondContact O-CG 3.41Å; R26-K28 PolarHBondContact O-N 3.27Å; K28-S30 PolarHBondContact O-N 3.1Å
29	R	44.9	Very low	45	Very low	231 Å²	231	136.2 Å²	136.2	87%	0.872	65%	0.645	S	S	*	*	P	Polyproline II helix	trans	-54.7	126.7	-179.3	-80.4	172	140.5	173.4	-8	109.9
30	S	52.9	Low	45.6	Very low	40 Å²	40	128.5 Å²	128.5	28%	0.28	64%	0.644	S	S	.	*	P	Polyproline II helix	trans	-54	143.2	170.5	52.6	0	0	0	0	110.1	K28 M77	K28-S30 PolarHBondContact O-N 3.1Å; S30-M77 WeakPolarHBondContact O-CE 3.34Å; S30-M77 VanDerWaalsContact OG-CE 3.26Å; S30-M77 WeakPolarHBondContact OG-CE 3.46Å; S30-M77 PolarHBondContact OG-SD 3Å
31	Q	54.1	Low	46.2	Very low	95 Å²	95	127.6 Å²	127.6	44%	0.444	64%	0.641	S	S	.	*	P	Polyproline II helix	trans	-83.4	132.5	174.4	-64.4	-168.5	28.9	0	0	109.5	P128 D131	Q31-P128 HydrophobicContact CB-CB 4.49Å; Q31-D131 VanDerWaalsContact NE2-CG 3.29Å; Q31-D131 PolarHBondContact NE2-OD1 3.22Å; Q31-D131 PolarHBondContact NE2-OD2 3.37Å
32	S	48.8	Very low	47.2	Very low	59 Å²	59	128.3 Å²	128.3	41%	0.413	64%	0.643	S	S	.	*	P	Polyproline II helix	trans	-57.9	134.4	-178.2	174.9	0	0	0	0	112.3	F36	S32-F36 WeakPolarHBondContact OG-CD2 3.37Å
33	S	56.2	Low	48.8	Very low	5 Å²	5	122.6 Å²	122.6	4%	0.035	61%	0.607	C	S	.	*	P	Polyproline II helix	trans	-60.9	147.3	163.7	81.3	0	0	0	0	109.6	Q35 F36	S33-Q35 PolarHBondContact O-N 3.29Å; S33-Q35 VanDerWaalsContact O-N 3.09Å; S33-F36 WeakPolarHBondContact O-CD2 3.14Å; S33-F36 PolarHBondContact O-N 3.41Å; S33-F36 WeakPolarHBondContact OG-CD2 2.99Å; S33-F36 WeakPolarHBondContact OG-CE2 3.44Å
34	S	52.9	Low	50.2	Low	75 Å²	75	119.8 Å²	119.8	52%	0.524	60%	0.603	S	S	.	*	G	3₁₀ helix	trans	-64.3	-14.5	-176	58.3	0	0	0	0	113.8	F36 R37	S34-F36 VanDerWaalsContact C-N 3.26Å; S34-F36 PolarHBondContact O-N 3.48Å; S34-R37 PolarHBondContact O-N 2.84Å
35	Q	58	Low	52.4	Low	75 Å²	75	110.9 Å²	110.9	35%	0.35	57%	0.565	S	S	.	*	G	3₁₀ helix	trans	-68.1	-22.1	-176.9	-69.9	-171.6	-24	0	0	113.9	S33 R37 F124 R125	S33-Q35 PolarHBondContact O-N 3.29Å; S33-Q35 VanDerWaalsContact O-N 3.09Å; Q35-R37 VanDerWaalsContact C-N 3.28Å; Q35-R37 PolarHBondContact O-N 3.37Å; Q35-F124 PolarHBondContact NE2-O 3.13Å; Q35-R125 VanDerWaalsContact CD-CB 3.47Å; Q35-R125 HydrophobicContact CG-CB 4.06Å
36	F	57.9	Low	54.6	Low	37 Å²	37	111.2 Å²	111.2	16%	0.162	56%	0.558	C	S	.	*	G	3₁₀ helix	trans	-77.8	-13.2	-177.3	-56.4	-55.3	0	0	0	113.3	S32 S33 S34 S38 I73 F74 D75	S32-F36 WeakPolarHBondContact OG-CD2 3.37Å; S33-F36 WeakPolarHBondContact O-CD2 3.14Å; S33-F36 PolarHBondContact O-N 3.41Å; S33-F36 WeakPolarHBondContact OG-CD2 2.99Å; S33-F36 WeakPolarHBondContact OG-CE2 3.44Å; S34-F36 VanDerWaalsContact C-N 3.26Å; S34-F36 PolarHBondContact O-N 3.48Å; F36-S38 PolarHBondContact O-N 3.05Å; F36-I73 HydrophobicContact CD1-CG2 4.24Å; F36-I73 HydrophobicContact CE1-CG2 3.75Å; F36-F74 WeakPolarHBondContact CE1-O 3.49Å; F36-D75 HydrophobicContact CB-CB 4.07Å; F36-D75 VanDerWaalsContact CD1-CA 3.41Å; F36-D75 HydrophobicContact CD1-CB 3.72Å; F36-D75 HydrophobicContact CE1-CB 4.38Å; F36-D75 HydrophobicContact CG-CB 3.94Å
37	R	45.3	Very low	57.2	Low	229 Å²	229	106.4 Å²	106.4	86%	0.864	55%	0.554	S	S	*	*	S	Bend	trans	-82.3	76.6	177.3	-76.1	-173.4	179.3	179.1	1.8	111.6	S34 Q35	S34-R37 PolarHBondContact O-N 2.84Å; Q35-R37 VanDerWaalsContact C-N 3.28Å; Q35-R37 PolarHBondContact O-N 3.37Å
38	S	43.6	Very low	59.8	Low	106 Å²	106	98.7 Å²	98.7	74%	0.741	52%	0.519	S	S	*	.			trans	159.1	79.6	148.4	168	0	0	0	0	111.7	F36	F36-S38 PolarHBondContact O-N 3.05Å
39	Q	48.9	Very low	62	Low	142 Å²	142	93.9 Å²	93.9	66%	0.664	51%	0.505	S	S	*	.			trans	-152.1	95.9	145.2	-66	-160	14.8	0	0	109.6	K41 I43	Q39-K41 PolarHBondContact O-N 3.3Å; Q39-I43 HydrophobicContact CB-CD1 4.26Å; Q39-I43 HydrophobicContact CB-CG1 4.37Å; Q39-I43 HydrophobicContact CG-CD1 4.47Å
40	G	47.8	Very low	64.3	Low	91 Å²	91	85.9 Å²	85.9	94%	0.938	48%	0.48	S	S	*	.			trans	-77.4	14	175.6	0	0	0	0	0	114.7
41	K	53.2	Low	66.2	Low	170 Å²	170	84.2 Å²	84.2	74%	0.739	47%	0.467	S	S	*	.	S	Bend	trans	-117.9	140.7	174.8	-74.9	-173.7	177.9	-178.2	0	108.8	Q39 I43	Q39-K41 PolarHBondContact O-N 3.3Å; K41-I43 PolarHBondContact O-N 2.72Å
42	P	60.7	Low	68	Low	110 Å²	110	87.4 Å²	87.4	71%	0.714	48%	0.48	S	S	*	.			trans	-56.7	127.1	174	23	-30.9	0	0	0	109.1	E44	P42-E44 PolarHBondContact O-N 3.23Å
43	I	67.8	Low	70	Confident	27 Å²	27	89.8 Å²	89.8	14%	0.138	49%	0.488	C	S	.	.			trans	-84.7	103	-178.2	-50.9	174.7	0	0	0	108.2	Q39 K41 V72 F74	Q39-I43 HydrophobicContact CB-CD1 4.26Å; Q39-I43 HydrophobicContact CB-CG1 4.37Å; Q39-I43 HydrophobicContact CG-CD1 4.47Å; K41-I43 PolarHBondContact O-N 2.72Å; I43-V72 HydrophobicContact CB-CG1 4.38Å; I43-V72 HydrophobicContact CD1-CG1 4.22Å; I43-V72 HydrophobicContact CG2-CG1 3.35Å; I43-V72 HydrophobicContact CG2-CG2 4.39Å; I43-F74 HydrophobicContact CB-CE1 4.37Å
44	E	67.8	Low	71.7	Confident	158 Å²	158	90.5 Å²	90.5	74%	0.738	49%	0.492	S	S	*	.			trans	-94.1	112.7	176.5	-72	-171	161.8	0	0	110.8	P42	P42-E44 PolarHBondContact O-N 3.23Å
45	L	82	Confident	73.6	Confident	11 Å²	11	90.4 Å²	90.4	6%	0.058	49%	0.49	C	S	.	.	P	Polyproline II helix	trans	-78	129.2	166.7	-67.5	176.3	0	0	0	109.2	P47 Q69 V72 F74 M85 Y88 K89	L45-P47 VanDerWaalsContact O-CD 3.32Å; L45-P47 WeakPolarHBondContact O-CD 3.04Å; L45-Q69 HydrophobicContact CD2-CB 4.16Å; L45-V72 HydrophobicContact CD2-CB 3.94Å; L45-V72 HydrophobicContact CD2-CG1 4.29Å; L45-V72 HydrophobicContact CD2-CG2 3.73Å; L45-F74 HydrophobicContact CD1-CE2 3.88Å; L45-F74 HydrophobicContact CD1-CZ 3.64Å; L45-F74 HydrophobicContact CG-CZ 4.05Å; L45-M85 HydrophobicContact CB-SD 4.02Å; L45-Y88 HydrophobicContact CB-CD1 3.8Å; L45-Y88 HydrophobicContact CB-CE1 3.87Å; L45-Y88 HydrophobicContact CD1-CD1 3.69Å; L45-Y88 HydrophobicContact CD1-CE1 4.21Å; L45-Y88 HydrophobicContact CG-CD1 4.4Å; L45-K89 HydrophobicContact CD1-CB 4.05Å
46	T	86.4	Confident	75.1	Confident	94 Å²	94	91.5 Å²	91.5	58%	0.577	51%	0.505	S	S	*	.	P	Polyproline II helix	trans	-70.8	121.4	174.6	-46.3	0	0	0	0	109.9	L48 Q69 Y88	T46-L48 PolarHBondContact O-N 3.38Å; T46-Q69 PolarHBondContact O-NE2 3.22Å; T46-Q69 PolarHBondContact O-OE1 3.18Å; T46-Y88 PolarHBondContact O-OH 2.7Å
47	P	88.2	Confident	76.7	Confident	107 Å²	107	94.6 Å²	94.6	70%	0.695	53%	0.532	S	S	*	.	P	Polyproline II helix	trans	-59.3	125.1	174.8	-24.8	35.8	0	0	0	111.5	L45 Y88	L45-P47 VanDerWaalsContact O-CD 3.32Å; L45-P47 WeakPolarHBondContact O-CD 3.04Å; P47-Y88 WeakPolarHBondContact CA-OH 3.47Å; P47-Y88 HydrophobicContact CB-CE2 4.41Å
48	L	92	Very high	78.9	Confident	38 Å²	38	88.7 Å²	88.7	20%	0.199	51%	0.514	C	S	.	.			trans	-109.9	147.5	177.3	-66.8	178.7	0	0	0	109.6	T46 L62 K65 K66 Q69 Y88	T46-L48 PolarHBondContact O-N 3.38Å; L48-L62 HydrophobicContact CB-CD1 4.05Å; L48-L62 HydrophobicContact CD1-CD1 4.29Å; L48-K65 HydrophobicContact CD1-CB 3.88Å; L48-K66 HydrophobicContact CB-CG 4.49Å; L48-K66 HydrophobicContact CD1-CG 3.78Å; L48-Q69 VanDerWaalsContact CD1-CD 3.45Å; L48-Q69 HydrophobicContact CD1-CG 4.27Å; L48-Y88 PolarHBondContact N-OH 3.23Å
49	P	93.4	Very high	81.2	Confident	71 Å²	71	85.2 Å²	85.2	46%	0.461	49%	0.486	S	S	.	.			trans	-60.1	160	177.1	25.8	-33.9	0	0	0	111.6	V54 L62 K66	P49-V54 HydrophobicContact CB-CG1 4.03Å; P49-V54 HydrophobicContact CG-CG1 3.92Å; P49-L62 HydrophobicContact CG-CD1 4.06Å; P49-L62 HydrophobicContact CG-CD2 3.96Å; P49-K66 WeakPolarHBondContact O-CE 3.48Å; P49-K66 PolarHBondContact O-NZ 3.19Å
50	L	93.3	Very high	83.3	Confident	64 Å²	64	80.9 Å²	80.9	34%	0.335	47%	0.47	S	S	.	.			trans	-71.8	143.1	173.2	-57.4	174.8	0	0	0	109.6	K52 D53 E95	L50-K52 HydrophobicContact CB-CG 4.07Å; L50-K52 PolarHBondContact O-N 2.96Å; L50-D53 HydrophobicContact CB-CB 4.38Å; L50-D53 WeakPolarHBondContact CB-OD2 3.41Å; L50-D53 PolarHBondContact O-N 2.89Å; L50-E95 WeakPolarHBondContact CA-OE1 3.38Å; L50-E95 WeakPolarHBondContact CB-OE1 3.44Å
51	L	91.9	Very high	85.4	Confident	4 Å²	4	82.1 Å²	82.1	2%	0.021	45%	0.451	C	S	.	.	G	3₁₀ helix	trans	-58.2	-34.5	178.2	-78.1	161.4	0	0	0	111.9	D53 V54 Q59 L62 F63 K66 E95 L96 Y99	L51-D53 VanDerWaalsContact C-N 3.27Å; L51-D53 PolarHBondContact O-N 3.39Å; L51-V54 WeakPolarHBondContact O-CG2 3.46Å; L51-Q59 HydrophobicContact CD2-CB 4.26Å; L51-Q59 HydrophobicContact CD2-CG 4.48Å; L51-Q59 WeakPolarHBondContact O-CG 3.49Å; L51-Q59 PolarHBondContact O-NE2 3.23Å; L51-L62 HydrophobicContact CD2-CB 4.11Å; L51-L62 HydrophobicContact CD2-CD2 3.94Å; L51-L62 HydrophobicContact CD2-CG 3.97Å; L51-L62 HydrophobicContact CG-CD2 4.31Å; L51-F63 HydrophobicContact CD1-CD2 4.27Å; L51-F63 HydrophobicContact CD2-CB 4.21Å; L51-K66 HydrophobicContact CD1-CD 4.04Å; L51-K66 HydrophobicContact CG-CD 4.07Å; L51-E95 HydrophobicContact CD1-CG 4.19Å; L51-E95 PolarHBondContact N-OE1 2.72Å; L51-L96 HydrophobicContact CD1-CD2 4.41Å; L51-Y99 HydrophobicContact CB-CD2 4.14Å; L51-Y99 HydrophobicContact CD1-CD1 4.08Å; L51-Y99 HydrophobicContact CD1-CD2 3.93Å; L51-Y99 HydrophobicContact CD1-CG 3.68Å; L51-Y99 HydrophobicContact CD2-CD2 4.46Å; L51-Y99 HydrophobicContact CD2-CE2 4.31Å; L51-Y99 HydrophobicContact CG-CD2 4.4Å
52	K	91.3	Very high	87.4	Confident	162 Å²	162	74.7 Å²	74.7	70%	0.704	42%	0.42	S	S	*	.	G	3₁₀ helix	trans	-71.3	-19.6	176.8	70	-179	-174.6	-176.5	0	114	L50	L50-K52 HydrophobicContact CB-CG 4.07Å; L50-K52 PolarHBondContact O-N 2.96Å
53	D	92.3	Very high	89.1	Confident	110 Å²	110	69.5 Å²	69.5	59%	0.588	39%	0.386	S	S	*	.	G	3₁₀ helix	trans	-95	-6.7	-175	-62.4	-22.2	0	0	0	112.4	L50 L51	L50-D53 HydrophobicContact CB-CB 4.38Å; L50-D53 WeakPolarHBondContact CB-OD2 3.41Å; L50-D53 PolarHBondContact O-N 2.89Å; L51-D53 VanDerWaalsContact C-N 3.27Å; L51-D53 PolarHBondContact O-N 3.39Å
54	V	91.7	Very high	90.4	Very high	20 Å²	20	69.5 Å²	69.5	12%	0.121	39%	0.386	C	S	.	.	S	Bend	trans	-106.7	150.8	177.9	-60	0	0	0	0	111.9	P49 L51 E58 Q59 L62	P49-V54 HydrophobicContact CB-CG1 4.03Å; P49-V54 HydrophobicContact CG-CG1 3.92Å; L51-V54 WeakPolarHBondContact O-CG2 3.46Å; V54-E58 HydrophobicContact CB-CB 4.45Å; V54-Q59 HydrophobicContact CG2-CG 3.65Å; V54-Q59 PolarHBondContact O-NE2 3.02Å; V54-L62 HydrophobicContact CB-CD2 4.41Å; V54-L62 HydrophobicContact CG1-CD2 3.91Å; V54-L62 HydrophobicContact CG2-CD2 3.59Å
55	P	91.9	Very high	91.7	Very high	73 Å²	73	66.2 Å²	66.2	47%	0.474	37%	0.369	S	S	.	.			trans	-56.1	146.2	174.8	-23.2	33.4	0	0	0	112.2	S57 E58 Q59	P55-S57 PolarHBondContact O-N 3.49Å; P55-E58 PolarHBondContact O-N 3.29Å; P55-Q59 PolarHBondContact O-N 3.17Å
56	S	89.1	Confident	92.4	Very high	97 Å²	97	65.8 Å²	65.8	68%	0.678	37%	0.367	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.7	-23.8	-179	-54.3	0	0	0	0	114.3	P60	S56-P60 WeakPolarHBondContact O-CD 3.41Å
57	S	91.1	Very high	92.9	Very high	102 Å²	102	61.3 Å²	61.3	71%	0.713	34%	0.34	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.8	-27.9	174.5	51	0	0	0	0	114	P55	P55-S57 PolarHBondContact O-N 3.49Å
58	E	92.1	Very high	93.2	Very high	106 Å²	106	60.7 Å²	60.7	50%	0.495	33%	0.328	S	S	.	.	T	Hydrogen-bonded Turn	trans	-96.4	-18.1	-178	-65.3	179.4	-160	0	0	112.6	V54 P55 P60 E61 L62	V54-E58 HydrophobicContact CB-CB 4.45Å; P55-E58 PolarHBondContact O-N 3.29Å; E58-P60 VanDerWaalsContact C-CD 3.48Å; E58-E61 PolarHBondContact O-N 3.02Å; E58-L62 PolarHBondContact O-N 2.7Å; E58-L62 VanDerWaalsContact O-N 3.1Å
59	Q	92.7	Very high	93.3	Very high	32 Å²	32	60.2 Å²	60.2	15%	0.15	32%	0.324	C	S	.	.	H	α-helix	trans	-54.5	-41.9	-179.3	-69.9	179.3	0.2	0	0	114	L51 V54 P55 E61 L62 F63 Y99	L51-Q59 HydrophobicContact CD2-CB 4.26Å; L51-Q59 HydrophobicContact CD2-CG 4.48Å; L51-Q59 WeakPolarHBondContact O-CG 3.49Å; L51-Q59 PolarHBondContact O-NE2 3.23Å; V54-Q59 HydrophobicContact CG2-CG 3.65Å; V54-Q59 PolarHBondContact O-NE2 3.02Å; P55-Q59 PolarHBondContact O-N 3.17Å; Q59-E61 PolarHBondContact O-N 3.11Å; Q59-L62 PolarHBondContact O-N 3.3Å; Q59-F63 VanDerWaalsContact O-CB 3.23Å; Q59-F63 WeakPolarHBondContact O-CB 3.32Å; Q59-F63 PolarHBondContact O-N 3.41Å; Q59-Y99 HydrophobicContact CB-CE2 4.23Å; Q59-Y99 WeakPolarHBondContact CB-OH 3.11Å
60	P	91.9	Very high	93.5	Very high	52 Å²	52	56.9 Å²	56.9	34%	0.338	30%	0.303	S	S	.	.	H	α-helix	trans	-61.5	-43.8	179.4	-25	35.5	0	0	0	113.4	S56 E58 F63 L64	S56-P60 WeakPolarHBondContact O-CD 3.41Å; E58-P60 VanDerWaalsContact C-CD 3.48Å; P60-F63 WeakPolarHBondContact O-CB 3.48Å; P60-F63 PolarHBondContact O-N 3.44Å; P60-L64 WeakPolarHBondContact O-CG 3.5Å; P60-L64 PolarHBondContact O-N 3.41Å
61	E	93.2	Very high	93.6	Very high	116 Å²	116	54.8 Å²	54.8	54%	0.542	29%	0.293	S	S	.	.	H	α-helix	trans	-69.2	-41.7	179.4	-168.9	-171.2	151.8	0	0	111.2	E58 Q59 F63 L64 K65	E58-E61 PolarHBondContact O-N 3.02Å; Q59-E61 PolarHBondContact O-N 3.11Å; E61-F63 VanDerWaalsContact C-N 3.3Å; E61-F63 PolarHBondContact O-N 3.28Å; E61-L64 PolarHBondContact O-N 3.47Å; E61-K65 WeakPolarHBondContact O-CG 3.48Å; E61-K65 PolarHBondContact O-N 3.19Å; E61-K65 VanDerWaalsContact O-N 3.07Å; E61-K65 WeakPolarHBondContact OE1-CE 3.44Å; E61-K65 IonicContact OE1-NZ 3.99Å; E61-K65 PolarHBondContact OE1-NZ 3.07Å
62	L	94.8	Very high	93.6	Very high	14 Å²	14	56.4 Å²	56.4	7%	0.073	30%	0.303	C	S	.	.	H	α-helix	trans	-62.1	-39.3	175.7	-178.5	60.1	0	0	0	111.8	L48 P49 L51 V54 E58 Q59 K65 K66	L48-L62 HydrophobicContact CB-CD1 4.05Å; L48-L62 HydrophobicContact CD1-CD1 4.29Å; P49-L62 HydrophobicContact CG-CD1 4.06Å; P49-L62 HydrophobicContact CG-CD2 3.96Å; L51-L62 HydrophobicContact CD2-CB 4.11Å; L51-L62 HydrophobicContact CD2-CD2 3.94Å; L51-L62 HydrophobicContact CD2-CG 3.97Å; L51-L62 HydrophobicContact CG-CD2 4.31Å; V54-L62 HydrophobicContact CB-CD2 4.41Å; V54-L62 HydrophobicContact CG1-CD2 3.91Å; V54-L62 HydrophobicContact CG2-CD2 3.59Å; E58-L62 PolarHBondContact O-N 2.7Å; E58-L62 VanDerWaalsContact O-N 3.1Å; Q59-L62 PolarHBondContact O-N 3.3Å; L62-K65 PolarHBondContact O-N 2.85Å; L62-K66 HydrophobicContact CG-CD 4.38Å; L62-K66 WeakPolarHBondContact O-CG 3.34Å; L62-K66 PolarHBondContact O-N 3.4Å
63	F	95.5	Very high	93.7	Very high	1 Å²	1	51 Å²	51	0%	0.004	28%	0.281	C	S	.	.	H	α-helix	trans	-59.8	-46.1	176	-179.1	-119.2	0	0	0	111.4	L51 Q59 P60 E61 K65 K66 L67 L96 Y99 T111 F157	L51-F63 HydrophobicContact CD1-CD2 4.27Å; L51-F63 HydrophobicContact CD2-CB 4.21Å; Q59-F63 VanDerWaalsContact O-CB 3.23Å; Q59-F63 WeakPolarHBondContact O-CB 3.32Å; Q59-F63 PolarHBondContact O-N 3.41Å; P60-F63 WeakPolarHBondContact O-CB 3.48Å; P60-F63 PolarHBondContact O-N 3.44Å; E61-F63 VanDerWaalsContact C-N 3.3Å; E61-F63 PolarHBondContact O-N 3.28Å; F63-K65 PolarHBondContact O-N 2.67Å; F63-K66 PolarHBondContact O-N 3.31Å; F63-L67 HydrophobicContact CD1-CD1 4.12Å; F63-L67 HydrophobicContact CE1-CD1 3.82Å; F63-L67 HydrophobicContact CZ-CD1 4.08Å; F63-L67 HydrophobicContact CZ-CG 4.44Å; F63-L67 WeakPolarHBondContact O-CG 3.46Å; F63-L67 PolarHBondContact O-N 3.2Å; F63-L96 HydrophobicContact CD2-CD2 3.3Å; F63-L96 HydrophobicContact CE2-CB 4.41Å; F63-L96 HydrophobicContact CE2-CD2 3.3Å; F63-L96 HydrophobicContact CE2-CG 4.42Å; F63-L96 HydrophobicContact CG-CD2 4.5Å; F63-L96 HydrophobicContact CZ-CD2 4.49Å; F63-Y99 HydrophobicContact CB-CE1 4.04Å; F63-Y99 HydrophobicContact CD1-CE1 4.21Å; F63-Y99 AromaticContact CD2-CD1 3.44Å; F63-Y99 HydrophobicContact CD2-CD1 3.44Å; F63-Y99 VanDerWaalsContact CD2-CD1 3.44Å; F63-Y99 AromaticContact CD2-CE1 3.68Å; F63-Y99 HydrophobicContact CD2-CE1 3.68Å; F63-Y99 HydrophobicContact CD2-CG 4.46Å; F63-Y99 AromaticContact CE2-CD1 3.59Å; F63-Y99 HydrophobicContact CE2-CD1 3.59Å; F63-Y99 HydrophobicContact CE2-CE1 4.12Å; F63-Y99 HydrophobicContact CG-CD1 4.01Å; F63-Y99 AromaticContact CG-CE1 3.73Å; F63-Y99 HydrophobicContact CG-CE1 3.73Å; F63-Y99 HydrophobicContact CZ-CD1 4.25Å; F63-T111 HydrophobicContact CD1-CG2 4.21Å; F63-T111 HydrophobicContact CE1-CG2 3.59Å; F63-F157 HydrophobicContact CE2-CE2 4.13Å; F63-F157 HydrophobicContact CE2-CZ 4.4Å; F63-F157 AromaticContact CZ-CE2 3.93Å; F63-F157 HydrophobicContact CZ-CE2 3.93Å; F63-F157 AromaticContact CZ-CZ 3.86Å; F63-F157 HydrophobicContact CZ-CZ 3.86Å
64	L	95.5	Very high	93.6	Very high	27 Å²	27	45.9 Å²	45.9	14%	0.141	25%	0.254	C	S	.	.	H	α-helix	trans	-61.5	-43.1	175.4	-62.5	176.3	0	0	0	112.1	P60 E61 K66 L67 Q68 Q110 E114	P60-L64 WeakPolarHBondContact O-CG 3.5Å; P60-L64 PolarHBondContact O-N 3.41Å; E61-L64 PolarHBondContact O-N 3.47Å; L64-K66 VanDerWaalsContact C-N 3.35Å; L64-K66 PolarHBondContact O-N 3.39Å; L64-L67 HydrophobicContact CD2-CD1 4.46Å; L64-L67 PolarHBondContact O-N 3.02Å; L64-Q68 WeakPolarHBondContact O-CG 3.38Å; L64-Q68 PolarHBondContact O-N 2.82Å; L64-Q110 HydrophobicContact CD1-CB 4.43Å; L64-E114 HydrophobicContact CD2-CB 4.13Å; L64-E114 HydrophobicContact CD2-CG 4.01Å
65	K	95.2	Very high	93.4	Very high	89 Å²	89	47.2 Å²	47.2	39%	0.387	26%	0.26	S	S	.	.	H	α-helix	trans	-61.7	-41.3	176.5	-71.4	175	-176	165.8	0	112.1	L48 E61 L62 F63 Q68 Q69	L48-K65 HydrophobicContact CD1-CB 3.88Å; E61-K65 WeakPolarHBondContact O-CG 3.48Å; E61-K65 PolarHBondContact O-N 3.19Å; E61-K65 VanDerWaalsContact O-N 3.07Å; E61-K65 WeakPolarHBondContact OE1-CE 3.44Å; E61-K65 IonicContact OE1-NZ 3.99Å; E61-K65 PolarHBondContact OE1-NZ 3.07Å; L62-K65 PolarHBondContact O-N 2.85Å; F63-K65 PolarHBondContact O-N 2.67Å; K65-Q68 WeakPolarHBondContact O-CB 3.28Å; K65-Q68 PolarHBondContact O-N 2.85Å; K65-Q69 PolarHBondContact O-N 3.48Å
66	K	96.8	Very high	93.3	Very high	2 Å²	2	45.2 Å²	45.2	1%	0.009	24%	0.244	C	C	.	.	H	α-helix	trans	-65.4	-42.4	175.7	-75.1	177.2	-178.5	-87	0	111.8	L48 P49 L51 L62 F63 L64 Q68 Q69 C70 T92 E95 L96	L48-K66 HydrophobicContact CB-CG 4.49Å; L48-K66 HydrophobicContact CD1-CG 3.78Å; P49-K66 WeakPolarHBondContact O-CE 3.48Å; P49-K66 PolarHBondContact O-NZ 3.19Å; L51-K66 HydrophobicContact CD1-CD 4.04Å; L51-K66 HydrophobicContact CG-CD 4.07Å; L62-K66 HydrophobicContact CG-CD 4.38Å; L62-K66 WeakPolarHBondContact O-CG 3.34Å; L62-K66 PolarHBondContact O-N 3.4Å; F63-K66 PolarHBondContact O-N 3.31Å; L64-K66 VanDerWaalsContact C-N 3.35Å; L64-K66 PolarHBondContact O-N 3.39Å; K66-Q68 VanDerWaalsContact C-N 3.28Å; K66-Q68 PolarHBondContact O-N 3.47Å; K66-Q69 PolarHBondContact O-N 2.86Å; K66-C70 PolarHBondContact O-N 2.9Å; K66-C70 PolarHBondContact O-SG 2.65Å; K66-C70 VanDerWaalsContact O-SG 3.38Å; K66-T92 HydrophobicContact CB-CG2 3.94Å; K66-T92 HydrophobicContact CD-CG2 4.22Å; K66-T92 HydrophobicContact CG-CG2 4Å; K66-E95 WeakPolarHBondContact CE-OE2 3.23Å; K66-E95 IonicContact NZ-OE1 2.85Å; K66-E95 IonicContact NZ-OE2 3.54Å; K66-E95 PolarHBondContact NZ-OE2 3.14Å; K66-L96 HydrophobicContact CB-CD1 4.44Å; K66-L96 HydrophobicContact CB-CD2 3.84Å; K66-L96 HydrophobicContact CB-CG 4.48Å; K66-L96 HydrophobicContact CD-CD2 4.44Å
67	L	96.9	Very high	93.1	Very high	0 Å²	0	43.3 Å²	43.3	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-57.4	-42.1	172.8	-71.6	171.8	0	0	0	111.7	F63 L64 C70 C71 L96 E114 V115 M118 F157	F63-L67 HydrophobicContact CD1-CD1 4.12Å; F63-L67 HydrophobicContact CE1-CD1 3.82Å; F63-L67 HydrophobicContact CZ-CD1 4.08Å; F63-L67 HydrophobicContact CZ-CG 4.44Å; F63-L67 WeakPolarHBondContact O-CG 3.46Å; F63-L67 PolarHBondContact O-N 3.2Å; L64-L67 HydrophobicContact CD2-CD1 4.46Å; L64-L67 PolarHBondContact O-N 3.02Å; L67-C70 PolarHBondContact O-N 3.1Å; L67-C71 PolarHBondContact O-N 3.35Å; L67-C71 PolarHBondContact O-SG 3.14Å; L67-C71 VanDerWaalsContact O-SG 3.33Å; L67-L96 HydrophobicContact CD2-CD1 4.08Å; L67-E114 HydrophobicContact CB-CB 4.46Å; L67-E114 HydrophobicContact CD1-CB 4.07Å; L67-V115 HydrophobicContact CD1-CG2 3.78Å; L67-V115 HydrophobicContact CD2-CG2 4.35Å; L67-M118 HydrophobicContact CD2-CB 4.4Å; L67-M118 HydrophobicContact CD2-CE 3.92Å; L67-M118 HydrophobicContact CD2-CG 4.32Å; L67-M118 WeakPolarHBondContact O-CG 3.38Å; L67-F157 HydrophobicContact CD2-CE1 3.91Å; L67-F157 HydrophobicContact CD2-CE2 4.46Å; L67-F157 HydrophobicContact CD2-CZ 3.67Å
68	Q	95.5	Very high	92.9	Very high	95 Å²	95	42.2 Å²	42.2	44%	0.444	21%	0.211	S	C	.	.	H	α-helix	trans	-62.4	-43.4	176.4	-72	170.8	-3.7	0	0	113.1	L64 K65 K66 C70 C71 E114 R117	L64-Q68 WeakPolarHBondContact O-CG 3.38Å; L64-Q68 PolarHBondContact O-N 2.82Å; K65-Q68 WeakPolarHBondContact O-CB 3.28Å; K65-Q68 PolarHBondContact O-N 2.85Å; K66-Q68 VanDerWaalsContact C-N 3.28Å; K66-Q68 PolarHBondContact O-N 3.47Å; Q68-C70 VanDerWaalsContact C-N 3.33Å; Q68-C70 PolarHBondContact O-N 2.93Å; Q68-C71 VanDerWaalsContact O-CB 3.31Å; Q68-C71 WeakPolarHBondContact O-CB 3.04Å; Q68-C71 PolarHBondContact O-N 3.1Å; Q68-E114 WeakPolarHBondContact CG-OE2 3.37Å; Q68-R117 VanDerWaalsContact CG-NH2 3.33Å
69	Q	93.7	Very high	92.6	Very high	27 Å²	27	42 Å²	42	13%	0.126	22%	0.218	C	C	.	.	H	α-helix	trans	-63.8	-37.9	175.6	-74.3	-170.2	-11.9	0	0	112.7	L45 T46 L48 K65 K66 C71 V72 Y88	L45-Q69 HydrophobicContact CD2-CB 4.16Å; T46-Q69 PolarHBondContact O-NE2 3.22Å; T46-Q69 PolarHBondContact O-OE1 3.18Å; L48-Q69 VanDerWaalsContact CD1-CD 3.45Å; L48-Q69 HydrophobicContact CD1-CG 4.27Å; K65-Q69 PolarHBondContact O-N 3.48Å; K66-Q69 PolarHBondContact O-N 2.86Å; Q69-C71 PolarHBondContact O-N 2.93Å; Q69-C71 VanDerWaalsContact O-N 3.12Å; Q69-V72 WeakPolarHBondContact O-CB 3.23Å; Q69-V72 PolarHBondContact O-N 3.49Å; Q69-V72 VanDerWaalsContact O-N 3.14Å; Q69-Y88 PolarHBondContact OE1-OH 3.29Å
70	C	96.5	Very high	92.3	Very high	2 Å²	2	47 Å²	47	1%	0.014	25%	0.245	C	C	.	.	T	Hydrogen-bonded Turn	trans	-67.3	-8.5	178.3	-71.6	0	0	0	0	114.2	K66 L67 Q68 V72 K89 L93 M118 N122	K66-C70 PolarHBondContact O-N 2.9Å; K66-C70 PolarHBondContact O-SG 2.65Å; K66-C70 VanDerWaalsContact O-SG 3.38Å; L67-C70 PolarHBondContact O-N 3.1Å; Q68-C70 VanDerWaalsContact C-N 3.33Å; Q68-C70 PolarHBondContact O-N 2.93Å; C70-V72 VanDerWaalsContact C-N 3.26Å; C70-V72 PolarHBondContact O-N 3.36Å; C70-K89 VanDerWaalsContact O-CE 3.23Å; C70-K89 WeakPolarHBondContact O-CE 3.42Å; C70-K89 PolarHBondContact O-NZ 2.99Å; C70-L93 HydrophobicContact CB-CD2 3.9Å; C70-L93 HydrophobicContact CB-CG 4.48Å; C70-M118 HydrophobicContact CB-CG 3.83Å; C70-M118 HydrophobicContact CB-SD 4.29Å; C70-N122 PolarHBondContact O-ND2 2.92Å
71	C	95.6	Very high	92.2	Very high	20 Å²	20	45.7 Å²	45.7	14%	0.135	24%	0.236	C	C	.	.	T	Hydrogen-bonded Turn	trans	-74.1	-15.7	172.1	-62.1	0	0	0	0	113.8	L67 Q68 Q69 I73 R117 M118 C121	L67-C71 PolarHBondContact O-N 3.35Å; L67-C71 PolarHBondContact O-SG 3.14Å; L67-C71 VanDerWaalsContact O-SG 3.33Å; Q68-C71 VanDerWaalsContact O-CB 3.31Å; Q68-C71 WeakPolarHBondContact O-CB 3.04Å; Q68-C71 PolarHBondContact O-N 3.1Å; Q69-C71 PolarHBondContact O-N 2.93Å; Q69-C71 VanDerWaalsContact O-N 3.12Å; C71-I73 PolarHBondContact O-N 3.16Å; C71-R117 PolarHBondContact SG-NH1 3.45Å; C71-R117 PolarHBondContact SG-NH2 2.88Å; C71-M118 VanDerWaalsContact SG-CA 3.54Å; C71-C121 HydrophobicContact CB-CB 4.39Å
72	V	93.3	Very high	91.9	Very high	37 Å²	37	42.9 Å²	42.9	22%	0.224	23%	0.225	C	C	.	.			trans	-68.2	124.8	175.1	170.4	0	0	0	0	109.7	I43 L45 Q69 C70 F74 K89	I43-V72 HydrophobicContact CB-CG1 4.38Å; I43-V72 HydrophobicContact CD1-CG1 4.22Å; I43-V72 HydrophobicContact CG2-CG1 3.35Å; I43-V72 HydrophobicContact CG2-CG2 4.39Å; L45-V72 HydrophobicContact CD2-CB 3.94Å; L45-V72 HydrophobicContact CD2-CG1 4.29Å; L45-V72 HydrophobicContact CD2-CG2 3.73Å; Q69-V72 WeakPolarHBondContact O-CB 3.23Å; Q69-V72 PolarHBondContact O-N 3.49Å; Q69-V72 VanDerWaalsContact O-N 3.14Å; C70-V72 VanDerWaalsContact C-N 3.26Å; C70-V72 PolarHBondContact O-N 3.36Å; V72-F74 HydrophobicContact CG1-CD2 4.49Å; V72-F74 HydrophobicContact CG1-CE1 4.34Å; V72-F74 HydrophobicContact CG1-CE2 3.89Å; V72-F74 HydrophobicContact CG1-CZ 3.8Å; V72-K89 WeakPolarHBondContact O-CD 3.34Å; V72-K89 PolarHBondContact O-NZ 3.48Å
73	I	91.9	Very high	91.7	Very high	48 Å²	48	47 Å²	47	25%	0.246	25%	0.247	C	C	.	.			trans	-97.4	134.7	179.7	-53.2	-54	0	0	0	109.5	F36 C71 C121 N122	F36-I73 HydrophobicContact CD1-CG2 4.24Å; F36-I73 HydrophobicContact CE1-CG2 3.75Å; C71-I73 PolarHBondContact O-N 3.16Å; I73-C121 WeakPolarHBondContact CD1-O 3.48Å; I73-N122 HydrophobicContact CD1-CB 4.26Å; I73-N122 VanDerWaalsContact CD1-OD1 3.23Å; I73-N122 WeakPolarHBondContact CD1-OD1 3.19Å
74	F	90.7	Very high	91.5	Very high	3 Å²	3	55.2 Å²	55.2	1%	0.013	28%	0.283	C	S	.	.			trans	-110.4	140.4	178.1	-67.8	-82	0	0	0	110.1	F36 I43 L45 V72 F76 D82 M85 K86 K89 H150	F36-F74 WeakPolarHBondContact CE1-O 3.49Å; I43-F74 HydrophobicContact CB-CE1 4.37Å; L45-F74 HydrophobicContact CD1-CE2 3.88Å; L45-F74 HydrophobicContact CD1-CZ 3.64Å; L45-F74 HydrophobicContact CG-CZ 4.05Å; V72-F74 HydrophobicContact CG1-CD2 4.49Å; V72-F74 HydrophobicContact CG1-CE1 4.34Å; V72-F74 HydrophobicContact CG1-CE2 3.89Å; V72-F74 HydrophobicContact CG1-CZ 3.8Å; F74-F76 HydrophobicContact CB-CE2 4.22Å; F74-F76 VanDerWaalsContact O-CD2 3.28Å; F74-F76 WeakPolarHBondContact O-CD2 3.42Å; F74-F76 PolarHBondContact O-N 2.89Å; F74-D82 HydrophobicContact CD1-CB 3.74Å; F74-D82 HydrophobicContact CE1-CB 4.06Å; F74-M85 HydrophobicContact CD1-CB 4.44Å; F74-M85 HydrophobicContact CE1-CB 3.44Å; F74-M85 VanDerWaalsContact CE1-CB 3.44Å; F74-M85 HydrophobicContact CZ-CB 3.58Å; F74-K86 HydrophobicContact CB-CD 4.45Å; F74-K86 HydrophobicContact CB-CG 3.75Å; F74-K86 HydrophobicContact CD1-CG 4.12Å; F74-K86 HydrophobicContact CD2-CG 4.41Å; F74-K86 HydrophobicContact CG-CG 3.83Å; F74-K89 HydrophobicContact CD2-CD 3.82Å; F74-K89 HydrophobicContact CE2-CB 3.92Å; F74-K89 HydrophobicContact CE2-CD 3.66Å; F74-K89 HydrophobicContact CE2-CG 4.41Å; F74-H150 AromaticContact CD2-CE1 3.8Å
75	D	87.7	Confident	91.3	Very high	49 Å²	49	55.8 Å²	55.8	26%	0.262	29%	0.285	S	S	.	.			trans	-76.4	112.8	174.5	-175.1	6	0	0	0	111.1	F36 M77 K86	F36-D75 HydrophobicContact CB-CB 4.07Å; F36-D75 VanDerWaalsContact CD1-CA 3.41Å; F36-D75 HydrophobicContact CD1-CB 3.72Å; F36-D75 HydrophobicContact CE1-CB 4.38Å; F36-D75 HydrophobicContact CG-CB 3.94Å; D75-M77 WeakPolarHBondContact OD1-CA 3.36Å; D75-M77 WeakPolarHBondContact OD1-CB 3.32Å; D75-M77 PolarHBondContact OD1-N 3.42Å; D75-K86 WeakPolarHBondContact O-CE 3.25Å; D75-K86 PolarHBondContact O-NZ 2.99Å
76	F	89.9	Confident	91.3	Very high	31 Å²	31	52.2 Å²	52.2	14%	0.136	27%	0.27	C	S	.	.	S	Bend	trans	-87.4	-9.4	176.1	-78.8	-96.3	0	0	0	113.5	F74 D78 K86 A146 S147 P149 H150	F74-F76 HydrophobicContact CB-CE2 4.22Å; F74-F76 VanDerWaalsContact O-CD2 3.28Å; F74-F76 WeakPolarHBondContact O-CD2 3.42Å; F74-F76 PolarHBondContact O-N 2.89Å; F76-D78 VanDerWaalsContact C-N 3.34Å; F76-K86 HydrophobicContact CE1-CD 4.22Å; F76-K86 HydrophobicContact CZ-CD 4.37Å; F76-K86 HydrophobicContact CZ-CG 4.26Å; F76-A146 HydrophobicContact CB-CB 3.95Å; F76-A146 WeakPolarHBondContact CB-O 3.32Å; F76-A146 WeakPolarHBondContact CD1-O 3.46Å; F76-S147 VanDerWaalsContact CD2-CB 3.48Å; F76-P149 HydrophobicContact CE1-CG 4.39Å; F76-H150 HydrophobicContact CE2-CB 4.42Å; F76-H150 AromaticContact CE2-CE1 3.84Å; F76-H150 AromaticContact CE2-CG 3.9Å; F76-H150 AromaticContact CE2-ND1 3.51Å; F76-H150 HydrophobicContact CZ-CB 4.38Å; F76-H150 AromaticContact CZ-CD2 3.76Å; F76-H150 AromaticContact CZ-CE1 3.54Å; F76-H150 AromaticContact CZ-CG 3.64Å; F76-H150 AromaticContact CZ-ND1 3.54Å; F76-H150 AromaticContact CZ-NE2 3.7Å
77	M	85.1	Confident	91.1	Very high	57 Å²	57	56 Å²	56	28%	0.281	29%	0.287	S	S	.	.	S	Bend	trans	-70.5	-34.3	174.9	-62.5	-56.1	-50.2	0	0	111.7	S30 D75 T79 A146	S30-M77 WeakPolarHBondContact O-CE 3.34Å; S30-M77 VanDerWaalsContact OG-CE 3.26Å; S30-M77 WeakPolarHBondContact OG-CE 3.46Å; S30-M77 PolarHBondContact OG-SD 3Å; D75-M77 WeakPolarHBondContact OD1-CA 3.36Å; D75-M77 WeakPolarHBondContact OD1-CB 3.32Å; D75-M77 PolarHBondContact OD1-N 3.42Å; M77-T79 PolarHBondContact O-N 3.31Å; M77-A146 HydrophobicContact SD-CB 4.03Å
78	D	87.5	Confident	91	Very high	78 Å²	78	58.4 Å²	58.4	42%	0.417	30%	0.297	S	S	.	.	S	Bend	trans	-82.9	98.5	160.9	-173.4	-10.2	0	0	0	109.4	F76 L80 S81 K86	F76-D78 VanDerWaalsContact C-N 3.34Å; D78-L80 PolarHBondContact O-N 3.41Å; D78-L80 PolarHBondContact OD1-N 2.82Å; D78-S81 WeakPolarHBondContact CB-OG 3.4Å; D78-S81 PolarHBondContact O-OG 2.85Å; D78-S81 VanDerWaalsContact O-OG 3.09Å; D78-S81 PolarHBondContact OD1-N 3.25Å; D78-S81 WeakPolarHBondContact OD2-CB 3.48Å; D78-K86 PolarHBondContact O-NZ 3.02Å
79	T	84.9	Confident	91.1	Very high	103 Å²	103	54 Å²	54	63%	0.632	28%	0.276	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.7	-12.2	-177.8	55	0	0	0	0	113.6	M77 L83	M77-T79 PolarHBondContact O-N 3.31Å; T79-L83 WeakPolarHBondContact O-CD2 3.49Å
80	L	86.7	Confident	91.2	Very high	137 Å²	137	58.2 Å²	58.2	72%	0.717	29%	0.291	S	S	*	.	T	Hydrogen-bonded Turn	trans	-111.2	-12.2	-175.4	-61	178.3	0	0	0	113.3	D78	D78-L80 PolarHBondContact O-N 3.41Å; D78-L80 PolarHBondContact OD1-N 2.82Å
81	S	88.6	Confident	91.2	Very high	23 Å²	23	61.1 Å²	61.1	16%	0.161	31%	0.311	C	S	.	.	T	Hydrogen-bonded Turn	trans	-73.7	148.8	175.3	63.8	0	0	0	0	112.7	D78 L83 K86	D78-S81 WeakPolarHBondContact CB-OG 3.4Å; D78-S81 PolarHBondContact O-OG 2.85Å; D78-S81 VanDerWaalsContact O-OG 3.09Å; D78-S81 PolarHBondContact OD1-N 3.25Å; D78-S81 WeakPolarHBondContact OD2-CB 3.48Å; S81-L83 PolarHBondContact O-N 3.46Å; S81-K86 WeakPolarHBondContact O-CE 3.4Å; S81-K86 PolarHBondContact O-NZ 2.94Å; S81-K86 PolarHBondContact OG-NZ 3.45Å; S81-K86 VanDerWaalsContact OG-NZ 3.1Å
82	D	86.9	Confident	91.3	Very high	57 Å²	57	60.4 Å²	60.4	31%	0.305	31%	0.306	S	S	.	.	T	Hydrogen-bonded Turn	trans	52	23.8	164.9	-56.2	-46.4	0	0	0	115.8	F74 K84 M85 K86	F74-D82 HydrophobicContact CD1-CB 3.74Å; F74-D82 HydrophobicContact CE1-CB 4.06Å; D82-K84 PolarHBondContact O-N 3.38Å; D82-K84 VanDerWaalsContact O-N 3.1Å; D82-M85 HydrophobicContact CB-CB 4.37Å; D82-M85 CarbonylContact O-C 3.56Å; D82-M85 WeakPolarHBondContact O-CA 3.44Å; D82-M85 PolarHBondContact O-N 3.03Å; D82-K86 HydrophobicContact CB-CG 4.4Å; D82-K86 PolarHBondContact O-N 2.75Å
83	L	90.7	Very high	91.5	Very high	102 Å²	102	58.6 Å²	58.6	53%	0.534	30%	0.295	S	S	.	.	H	α-helix	trans	-50.6	-44.5	-172.6	-67.7	177.3	0	0	0	112.8	T79 S81 M85 E87	T79-L83 WeakPolarHBondContact O-CD2 3.49Å; S81-L83 PolarHBondContact O-N 3.46Å; L83-M85 PolarHBondContact O-N 3.37Å; L83-E87 WeakPolarHBondContact O-CB 3.42Å; L83-E87 PolarHBondContact O-N 3.01Å
84	K	92.1	Very high	91.7	Very high	173 Å²	173	60 Å²	60	75%	0.752	30%	0.303	S	S	*	.	H	α-helix	trans	-63.1	-40.7	177.5	-173.1	-179.5	178.7	-175.8	0	112.2	D82 Y88	D82-K84 PolarHBondContact O-N 3.38Å; D82-K84 VanDerWaalsContact O-N 3.1Å; K84-Y88 VanDerWaalsContact O-CB 3.32Å; K84-Y88 WeakPolarHBondContact O-CB 3.41Å; K84-Y88 PolarHBondContact O-N 3.23Å
85	M	92.1	Very high	92	Very high	38 Å²	38	61.1 Å²	61.1	19%	0.187	31%	0.309	C	S	.	.	H	α-helix	trans	-78.3	-36.2	-178.1	-62.5	-60.3	166.6	0	0	111.9	L45 F74 D82 L83 E87 Y88 K89	L45-M85 HydrophobicContact CB-SD 4.02Å; F74-M85 HydrophobicContact CD1-CB 4.44Å; F74-M85 HydrophobicContact CE1-CB 3.44Å; F74-M85 VanDerWaalsContact CE1-CB 3.44Å; F74-M85 HydrophobicContact CZ-CB 3.58Å; D82-M85 HydrophobicContact CB-CB 4.37Å; D82-M85 CarbonylContact O-C 3.56Å; D82-M85 WeakPolarHBondContact O-CA 3.44Å; D82-M85 PolarHBondContact O-N 3.03Å; L83-M85 PolarHBondContact O-N 3.37Å; M85-E87 VanDerWaalsContact C-N 3.34Å; M85-Y88 PolarHBondContact O-N 3.07Å; M85-K89 WeakPolarHBondContact O-CB 3.47Å; M85-K89 PolarHBondContact O-N 2.96Å
86	K	93.6	Very high	92.5	Very high	15 Å²	15	58.8 Å²	58.8	7%	0.065	30%	0.296	C	S	.	.	H	α-helix	trans	-58.3	-46.8	168.8	-74	171.6	177.4	160.8	0	110.7	F74 D75 F76 D78 S81 D82 K89 R90 H150	F74-K86 HydrophobicContact CB-CD 4.45Å; F74-K86 HydrophobicContact CB-CG 3.75Å; F74-K86 HydrophobicContact CD1-CG 4.12Å; F74-K86 HydrophobicContact CD2-CG 4.41Å; F74-K86 HydrophobicContact CG-CG 3.83Å; D75-K86 WeakPolarHBondContact O-CE 3.25Å; D75-K86 PolarHBondContact O-NZ 2.99Å; F76-K86 HydrophobicContact CE1-CD 4.22Å; F76-K86 HydrophobicContact CZ-CD 4.37Å; F76-K86 HydrophobicContact CZ-CG 4.26Å; D78-K86 PolarHBondContact O-NZ 3.02Å; S81-K86 WeakPolarHBondContact O-CE 3.4Å; S81-K86 PolarHBondContact O-NZ 2.94Å; S81-K86 PolarHBondContact OG-NZ 3.45Å; S81-K86 VanDerWaalsContact OG-NZ 3.1Å; D82-K86 HydrophobicContact CB-CG 4.4Å; D82-K86 PolarHBondContact O-N 2.75Å; K86-K89 PolarHBondContact O-N 3.48Å; K86-R90 WeakPolarHBondContact O-CB 3.37Å; K86-R90 PolarHBondContact O-N 3.3Å; K86-H150 PolarHBondContact O-CE1 3.2Å; K86-H150 PolarHBondContact O-NE2 3.02Å
87	E	94.4	Very high	92.8	Very high	82 Å²	82	57.5 Å²	57.5	38%	0.383	29%	0.291	S	S	.	.	H	α-helix	trans	-65.3	-43.9	176.9	-176.2	54.2	-144.7	0	0	112	L83 M85 K89 R90 S91	L83-E87 WeakPolarHBondContact O-CB 3.42Å; L83-E87 PolarHBondContact O-N 3.01Å; M85-E87 VanDerWaalsContact C-N 3.34Å; E87-K89 PolarHBondContact O-N 3.37Å; E87-R90 WeakPolarHBondContact O-CB 3.37Å; E87-R90 PolarHBondContact O-N 3.29Å; E87-R90 VanDerWaalsContact O-N 3.16Å; E87-R90 IonicContact OE1-CZ 2.67Å; E87-R90 IonicContact OE1-NE 3.35Å; E87-R90 PolarHBondContact OE1-NE 3.23Å; E87-R90 VanDerWaalsContact OE1-NE 3.14Å; E87-R90 IonicContact OE1-NH2 3.16Å; E87-R90 PolarHBondContact OE1-NH2 3.46Å; E87-R90 IonicContact OE2-CZ 2.7Å; E87-R90 IonicContact OE2-NE 2.65Å; E87-R90 PolarHBondContact OE2-NE 3.46Å; E87-R90 VanDerWaalsContact OE2-NE 3.1Å; E87-R90 IonicContact OE2-NH1 2.92Å; E87-R90 PolarHBondContact OE2-NH1 2.98Å; E87-R90 IonicContact OE2-NH2 2.84Å; E87-R90 PolarHBondContact OE2-NH2 3.17Å; E87-S91 PolarHBondContact O-N 2.93Å
88	Y	94.4	Very high	93.3	Very high	49 Å²	49	58.7 Å²	58.7	19%	0.192	30%	0.298	C	S	.	.	H	α-helix	trans	-60.2	-44.7	177.1	177.3	-97.6	0	0	0	112.1	L45 T46 P47 L48 Q69 K84 M85 S91 T92	L45-Y88 HydrophobicContact CB-CD1 3.8Å; L45-Y88 HydrophobicContact CB-CE1 3.87Å; L45-Y88 HydrophobicContact CD1-CD1 3.69Å; L45-Y88 HydrophobicContact CD1-CE1 4.21Å; L45-Y88 HydrophobicContact CG-CD1 4.4Å; T46-Y88 PolarHBondContact O-OH 2.7Å; P47-Y88 WeakPolarHBondContact CA-OH 3.47Å; P47-Y88 HydrophobicContact CB-CE2 4.41Å; L48-Y88 PolarHBondContact N-OH 3.23Å; Q69-Y88 PolarHBondContact OE1-OH 3.29Å; K84-Y88 VanDerWaalsContact O-CB 3.32Å; K84-Y88 WeakPolarHBondContact O-CB 3.41Å; K84-Y88 PolarHBondContact O-N 3.23Å; M85-Y88 PolarHBondContact O-N 3.07Å; Y88-S91 PolarHBondContact O-N 3.36Å; Y88-T92 WeakPolarHBondContact O-CB 3.36Å; Y88-T92 PolarHBondContact O-N 2.82Å; Y88-T92 PolarHBondContact O-OG1 3.3Å
89	K	96.2	Very high	93.7	Very high	3 Å²	3	56 Å²	56	1%	0.013	28%	0.283	C	S	.	.	H	α-helix	trans	-62.2	-42.4	173.6	178	172.3	169.6	-170	0	111.6	L45 C70 V72 F74 M85 K86 E87 T92 L93 N122	L45-K89 HydrophobicContact CD1-CB 4.05Å; C70-K89 VanDerWaalsContact O-CE 3.23Å; C70-K89 WeakPolarHBondContact O-CE 3.42Å; C70-K89 PolarHBondContact O-NZ 2.99Å; V72-K89 WeakPolarHBondContact O-CD 3.34Å; V72-K89 PolarHBondContact O-NZ 3.48Å; F74-K89 HydrophobicContact CD2-CD 3.82Å; F74-K89 HydrophobicContact CE2-CB 3.92Å; F74-K89 HydrophobicContact CE2-CD 3.66Å; F74-K89 HydrophobicContact CE2-CG 4.41Å; M85-K89 WeakPolarHBondContact O-CB 3.47Å; M85-K89 PolarHBondContact O-N 2.96Å; K86-K89 PolarHBondContact O-N 3.48Å; E87-K89 PolarHBondContact O-N 3.37Å; K89-T92 PolarHBondContact O-N 3.25Å; K89-L93 HydrophobicContact CG-CD1 3.99Å; K89-L93 HydrophobicContact CG-CG 4.32Å; K89-L93 WeakPolarHBondContact O-CB 3.32Å; K89-L93 WeakPolarHBondContact O-CG 3.34Å; K89-L93 PolarHBondContact O-N 2.94Å; K89-N122 PolarHBondContact NZ-OD1 3.24Å
90	R	96.4	Very high	94.2	Very high	115 Å²	115	51.5 Å²	51.5	43%	0.434	25%	0.254	S	S	.	.	H	α-helix	trans	-58.1	-50.4	176.6	-172.1	-175.5	75.7	177.4	7.3	111.4	K86 E87 T92 L93 N94 L153	K86-R90 WeakPolarHBondContact O-CB 3.37Å; K86-R90 PolarHBondContact O-N 3.3Å; E87-R90 WeakPolarHBondContact O-CB 3.37Å; E87-R90 PolarHBondContact O-N 3.29Å; E87-R90 VanDerWaalsContact O-N 3.16Å; E87-R90 IonicContact OE1-CZ 2.67Å; E87-R90 IonicContact OE1-NE 3.35Å; E87-R90 PolarHBondContact OE1-NE 3.23Å; E87-R90 VanDerWaalsContact OE1-NE 3.14Å; E87-R90 IonicContact OE1-NH2 3.16Å; E87-R90 PolarHBondContact OE1-NH2 3.46Å; E87-R90 IonicContact OE2-CZ 2.7Å; E87-R90 IonicContact OE2-NE 2.65Å; E87-R90 PolarHBondContact OE2-NE 3.46Å; E87-R90 VanDerWaalsContact OE2-NE 3.1Å; E87-R90 IonicContact OE2-NH1 2.92Å; E87-R90 PolarHBondContact OE2-NH1 2.98Å; E87-R90 IonicContact OE2-NH2 2.84Å; E87-R90 PolarHBondContact OE2-NH2 3.17Å; R90-T92 VanDerWaalsContact C-N 3.3Å; R90-T92 PolarHBondContact O-N 3.43Å; R90-L93 PolarHBondContact O-N 3.18Å; R90-N94 PolarHBondContact O-N 3.35Å; R90-L153 HydrophobicContact CG-CD1 3.74Å; R90-L153 WeakPolarHBondContact O-CD1 3.26Å
91	S	96.7	Very high	94.5	Very high	63 Å²	63	48.4 Å²	48.4	44%	0.441	24%	0.241	S	C	.	.	H	α-helix	trans	-61.2	-39.2	177.3	-174.3	0	0	0	0	112.1	E87 Y88 N94 E95	E87-S91 PolarHBondContact O-N 2.93Å; Y88-S91 PolarHBondContact O-N 3.36Å; S91-N94 PolarHBondContact O-N 2.88Å; S91-E95 WeakPolarHBondContact O-CB 3.36Å; S91-E95 PolarHBondContact O-N 2.78Å
92	T	97	Very high	94.6	Very high	5 Å²	5	53.8 Å²	53.8	3%	0.031	27%	0.267	C	S	.	.	H	α-helix	trans	-66.5	-44.5	177.6	-56.3	0	0	0	0	111.1	K66 Y88 K89 R90 N94 E95 L96	K66-T92 HydrophobicContact CB-CG2 3.94Å; K66-T92 HydrophobicContact CD-CG2 4.22Å; K66-T92 HydrophobicContact CG-CG2 4Å; Y88-T92 WeakPolarHBondContact O-CB 3.36Å; Y88-T92 PolarHBondContact O-N 2.82Å; Y88-T92 PolarHBondContact O-OG1 3.3Å; K89-T92 PolarHBondContact O-N 3.25Å; R90-T92 VanDerWaalsContact C-N 3.3Å; R90-T92 PolarHBondContact O-N 3.43Å; T92-N94 VanDerWaalsContact C-N 3.35Å; T92-N94 PolarHBondContact O-N 3.47Å; T92-E95 WeakPolarHBondContact O-CB 3.41Å; T92-E95 PolarHBondContact O-N 3.37Å; T92-L96 HydrophobicContact CG2-CD1 4.37Å; T92-L96 VanDerWaalsContact O-CG 3.25Å; T92-L96 WeakPolarHBondContact O-CG 3.49Å; T92-L96 PolarHBondContact O-N 3.49Å
93	L	97.8	Very high	94.6	Very high	0 Å²	0	52.5 Å²	52.5	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-61.1	-42.3	176	-75.8	169.7	0	0	0	111.9	C70 K89 R90 E95 L96 V97 M118 H150 L153 V154	C70-L93 HydrophobicContact CB-CD2 3.9Å; C70-L93 HydrophobicContact CB-CG 4.48Å; K89-L93 HydrophobicContact CG-CD1 3.99Å; K89-L93 HydrophobicContact CG-CG 4.32Å; K89-L93 WeakPolarHBondContact O-CB 3.32Å; K89-L93 WeakPolarHBondContact O-CG 3.34Å; K89-L93 PolarHBondContact O-N 2.94Å; R90-L93 PolarHBondContact O-N 3.18Å; L93-E95 VanDerWaalsContact C-N 3.35Å; L93-E95 PolarHBondContact O-N 3.21Å; L93-L96 HydrophobicContact CD2-CD1 4.45Å; L93-L96 WeakPolarHBondContact O-CB 3.18Å; L93-L96 PolarHBondContact O-N 3.12Å; L93-V97 WeakPolarHBondContact O-CG2 3.43Å; L93-V97 PolarHBondContact O-N 2.79Å; L93-M118 HydrophobicContact CD2-SD 4.28Å; L93-H150 HydrophobicContact CD1-CB 4.24Å; L93-L153 HydrophobicContact CB-CB 3.77Å; L93-L153 HydrophobicContact CB-CD1 3.79Å; L93-L153 HydrophobicContact CB-CG 4.43Å; L93-L153 HydrophobicContact CD1-CB 4.27Å; L93-V154 HydrophobicContact CD1-CG2 4.01Å; L93-V154 HydrophobicContact CD2-CG2 3.9Å
94	N	97.2	Very high	94.4	Very high	77 Å²	77	58.8 Å²	58.8	41%	0.412	28%	0.279	S	S	.	.	H	α-helix	trans	-60.7	-45.6	176.1	-165.3	92.7	0	0	0	111.4	R90 S91 T92 L96 V97 D98 L153	R90-N94 PolarHBondContact O-N 3.35Å; S91-N94 PolarHBondContact O-N 2.88Å; T92-N94 VanDerWaalsContact C-N 3.35Å; T92-N94 PolarHBondContact O-N 3.47Å; N94-L96 VanDerWaalsContact C-N 3.29Å; N94-L96 PolarHBondContact O-N 3.31Å; N94-V97 WeakPolarHBondContact O-CB 3.21Å; N94-V97 PolarHBondContact O-N 2.96Å; N94-D98 PolarHBondContact ND2-OD2 2.88Å; N94-D98 PolarHBondContact O-N 3.1Å; N94-L153 HydrophobicContact CB-CD1 4.47Å
95	E	97.1	Very high	94.1	Very high	27 Å²	27	53 Å²	53	13%	0.126	27%	0.268	C	S	.	.	H	α-helix	trans	-60.1	-38.7	175.3	-174.6	-173.2	-155	0	0	112.3	L50 L51 K66 S91 T92 L93 D98 Y99	L50-E95 WeakPolarHBondContact CA-OE1 3.38Å; L50-E95 WeakPolarHBondContact CB-OE1 3.44Å; L51-E95 HydrophobicContact CD1-CG 4.19Å; L51-E95 PolarHBondContact N-OE1 2.72Å; K66-E95 WeakPolarHBondContact CE-OE2 3.23Å; K66-E95 IonicContact NZ-OE1 2.85Å; K66-E95 IonicContact NZ-OE2 3.54Å; K66-E95 PolarHBondContact NZ-OE2 3.14Å; S91-E95 WeakPolarHBondContact O-CB 3.36Å; S91-E95 PolarHBondContact O-N 2.78Å; T92-E95 WeakPolarHBondContact O-CB 3.41Å; T92-E95 PolarHBondContact O-N 3.37Å; L93-E95 VanDerWaalsContact C-N 3.35Å; L93-E95 PolarHBondContact O-N 3.21Å; E95-D98 PolarHBondContact O-N 2.75Å; E95-Y99 VanDerWaalsContact O-CB 3.28Å; E95-Y99 WeakPolarHBondContact O-CB 3.46Å; E95-Y99 PolarHBondContact O-N 3.29Å
96	L	97.3	Very high	93.9	Very high	0 Å²	0	51.3 Å²	51.3	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-65.2	-37.9	176	-67.2	171.5	0	0	0	112.1	L51 F63 K66 L67 T92 L93 N94 I100 F157	L51-L96 HydrophobicContact CD1-CD2 4.41Å; F63-L96 HydrophobicContact CD2-CD2 3.3Å; F63-L96 HydrophobicContact CE2-CB 4.41Å; F63-L96 HydrophobicContact CE2-CD2 3.3Å; F63-L96 HydrophobicContact CE2-CG 4.42Å; F63-L96 HydrophobicContact CG-CD2 4.5Å; F63-L96 HydrophobicContact CZ-CD2 4.49Å; K66-L96 HydrophobicContact CB-CD1 4.44Å; K66-L96 HydrophobicContact CB-CD2 3.84Å; K66-L96 HydrophobicContact CB-CG 4.48Å; K66-L96 HydrophobicContact CD-CD2 4.44Å; L67-L96 HydrophobicContact CD2-CD1 4.08Å; T92-L96 HydrophobicContact CG2-CD1 4.37Å; T92-L96 VanDerWaalsContact O-CG 3.25Å; T92-L96 WeakPolarHBondContact O-CG 3.49Å; T92-L96 PolarHBondContact O-N 3.49Å; L93-L96 HydrophobicContact CD2-CD1 4.45Å; L93-L96 WeakPolarHBondContact O-CB 3.18Å; L93-L96 PolarHBondContact O-N 3.12Å; N94-L96 VanDerWaalsContact C-N 3.29Å; N94-L96 PolarHBondContact O-N 3.31Å; L96-I100 WeakPolarHBondContact O-CG2 3.31Å; L96-I100 PolarHBondContact O-N 3.33Å; L96-F157 HydrophobicContact CB-CD2 3.93Å; L96-F157 HydrophobicContact CB-CE2 3.94Å
97	V	97.1	Very high	93.8	Very high	4 Å²	4	51.3 Å²	51.3	2%	0.024	26%	0.261	C	S	.	.	H	α-helix	trans	-63.4	-45.8	174.2	172.9	0	0	0	0	110.8	L93 N94 I100 T101 E156 F157	L93-V97 WeakPolarHBondContact O-CG2 3.43Å; L93-V97 PolarHBondContact O-N 2.79Å; N94-V97 WeakPolarHBondContact O-CB 3.21Å; N94-V97 PolarHBondContact O-N 2.96Å; V97-I100 WeakPolarHBondContact O-CG2 3.43Å; V97-T101 WeakPolarHBondContact O-CB 3.4Å; V97-T101 PolarHBondContact O-N 2.91Å; V97-T101 PolarHBondContact O-OG1 3.02Å; V97-E156 HydrophobicContact CG1-CG 3.9Å; V97-E156 HydrophobicContact CG2-CB 4.48Å; V97-E156 HydrophobicContact CG2-CG 4.44Å; V97-F157 HydrophobicContact CG2-CB 3.77Å
98	D	95.5	Very high	93.7	Very high	81 Å²	81	50 Å²	50	43%	0.433	26%	0.259	S	S	.	.	H	α-helix	trans	-63.9	-46.2	178.2	-67.2	-29.8	0	0	0	110.7	N94 E95 T101 I102	N94-D98 PolarHBondContact ND2-OD2 2.88Å; N94-D98 PolarHBondContact O-N 3.1Å; E95-D98 PolarHBondContact O-N 2.75Å; D98-T101 PolarHBondContact O-N 3.38Å; D98-I102 WeakPolarHBondContact O-CG1 3.45Å; D98-I102 PolarHBondContact O-N 3.12Å; D98-I102 VanDerWaalsContact O-N 3.11Å
99	Y	95	Very high	93.6	Very high	23 Å²	23	53.9 Å²	53.9	9%	0.09	28%	0.279	C	S	.	.	H	α-helix	trans	-62.2	-47.2	-178.6	-178.1	-103.4	0	0	0	112.5	L51 Q59 F63 E95 T101 I102 S103 C106	L51-Y99 HydrophobicContact CB-CD2 4.14Å; L51-Y99 HydrophobicContact CD1-CD1 4.08Å; L51-Y99 HydrophobicContact CD1-CD2 3.93Å; L51-Y99 HydrophobicContact CD1-CG 3.68Å; L51-Y99 HydrophobicContact CD2-CD2 4.46Å; L51-Y99 HydrophobicContact CD2-CE2 4.31Å; L51-Y99 HydrophobicContact CG-CD2 4.4Å; Q59-Y99 HydrophobicContact CB-CE2 4.23Å; Q59-Y99 WeakPolarHBondContact CB-OH 3.11Å; F63-Y99 HydrophobicContact CB-CE1 4.04Å; F63-Y99 HydrophobicContact CD1-CE1 4.21Å; F63-Y99 AromaticContact CD2-CD1 3.44Å; F63-Y99 HydrophobicContact CD2-CD1 3.44Å; F63-Y99 VanDerWaalsContact CD2-CD1 3.44Å; F63-Y99 AromaticContact CD2-CE1 3.68Å; F63-Y99 HydrophobicContact CD2-CE1 3.68Å; F63-Y99 HydrophobicContact CD2-CG 4.46Å; F63-Y99 AromaticContact CE2-CD1 3.59Å; F63-Y99 HydrophobicContact CE2-CD1 3.59Å; F63-Y99 HydrophobicContact CE2-CE1 4.12Å; F63-Y99 HydrophobicContact CG-CD1 4.01Å; F63-Y99 AromaticContact CG-CE1 3.73Å; F63-Y99 HydrophobicContact CG-CE1 3.73Å; F63-Y99 HydrophobicContact CZ-CD1 4.25Å; E95-Y99 VanDerWaalsContact O-CB 3.28Å; E95-Y99 WeakPolarHBondContact O-CB 3.46Å; E95-Y99 PolarHBondContact O-N 3.29Å; Y99-T101 PolarHBondContact O-N 3.19Å; Y99-I102 PolarHBondContact O-N 3.25Å; Y99-S103 WeakPolarHBondContact CD2-OG 3.19Å; Y99-S103 WeakPolarHBondContact CE2-OG 3.42Å; Y99-S103 WeakPolarHBondContact O-CB 3.35Å; Y99-S103 PolarHBondContact O-N 3.5Å; Y99-S103 PolarHBondContact O-OG 2.95Å; Y99-S103 VanDerWaalsContact O-OG 3.13Å; Y99-C106 HydrophobicContact CE1-CB 3.71Å
100	I	94.7	Very high	93.4	Very high	7 Å²	7	60.2 Å²	60.2	4%	0.036	31%	0.308	C	S	.	.	H	α-helix	trans	-67.9	-24.8	179.4	-163.9	160.1	0	0	0	112.9	L96 V97 L107 F157 R160 F161	L96-I100 WeakPolarHBondContact O-CG2 3.31Å; L96-I100 PolarHBondContact O-N 3.33Å; V97-I100 WeakPolarHBondContact O-CG2 3.43Å; I100-L107 HydrophobicContact CD1-CD2 4.04Å; I100-L107 HydrophobicContact CG1-CD2 4.38Å; I100-F157 HydrophobicContact CB-CD2 4.43Å; I100-F157 HydrophobicContact CB-CE2 3.97Å; I100-F157 HydrophobicContact CD1-CD2 4.39Å; I100-F157 HydrophobicContact CD1-CE2 3.68Å; I100-F157 HydrophobicContact CD1-CZ 3.77Å; I100-F157 HydrophobicContact CG1-CE2 4.46Å; I100-F157 HydrophobicContact CG2-CD2 3.84Å; I100-F157 HydrophobicContact CG2-CE2 3.9Å; I100-R160 HydrophobicContact CG2-CB 3.82Å; I100-F161 HydrophobicContact CD1-CB 3.6Å; I100-F161 HydrophobicContact CD1-CD2 3.98Å; I100-F161 HydrophobicContact CD1-CG 4.28Å
101	T	93.4	Very high	93.4	Very high	72 Å²	72	55 Å²	55	44%	0.442	29%	0.289	S	S	.	.	H	α-helix	trans	-77.6	-37.3	179.7	-58.1	0	0	0	0	111.5	V97 D98 Y99 R160	V97-T101 WeakPolarHBondContact O-CB 3.4Å; V97-T101 PolarHBondContact O-N 2.91Å; V97-T101 PolarHBondContact O-OG1 3.02Å; D98-T101 PolarHBondContact O-N 3.38Å; Y99-T101 PolarHBondContact O-N 3.19Å; T101-R160 PolarHBondContact OG1-NH1 3.28Å; T101-R160 VanDerWaalsContact OG1-NH1 3.07Å
102	I	90.9	Very high	93.4	Very high	136 Å²	136	52 Å²	52	70%	0.697	27%	0.268	S	S	*	.	H	α-helix	trans	-100.9	-36.8	-170.9	-58.7	167.8	0	0	0	112.2	D98 Y99	D98-I102 WeakPolarHBondContact O-CG1 3.45Å; D98-I102 PolarHBondContact O-N 3.12Å; D98-I102 VanDerWaalsContact O-N 3.11Å; Y99-I102 PolarHBondContact O-N 3.25Å
103	S	87.9	Confident	93.4	Very high	31 Å²	31	53.5 Å²	53.5	22%	0.217	28%	0.278	C	S	.	.			trans	-80.1	127.7	-170.4	-61.1	0	0	0	0	112.5	Y99 C106	Y99-S103 WeakPolarHBondContact CD2-OG 3.19Å; Y99-S103 WeakPolarHBondContact CE2-OG 3.42Å; Y99-S103 WeakPolarHBondContact O-CB 3.35Å; Y99-S103 PolarHBondContact O-N 3.5Å; Y99-S103 PolarHBondContact O-OG 2.95Å; Y99-S103 VanDerWaalsContact O-OG 3.13Å; S103-C106 PolarHBondContact O-SG 3.28Å; S103-C106 VanDerWaalsContact O-SG 3.39Å
104	R	85.8	Confident	93.3	Very high	233 Å²	233	55.3 Å²	55.3	88%	0.879	29%	0.286	S	S	*	.	T	Hydrogen-bonded Turn	trans	-87.6	147	171.2	-63.5	-171.7	-178.4	-169.6	-0.1	111.2	C106 E166	R104-C106 VanDerWaalsContact C-N 3.26Å; R104-C106 PolarHBondContact O-N 3.47Å; R104-E166 WeakPolarHBondContact CA-OE1 3.28Å; R104-E166 WeakPolarHBondContact CB-OE1 3.34Å
105	G	85.3	Confident	93.3	Very high	51 Å²	51	51.7 Å²	51.7	53%	0.526	27%	0.267	S	S	.	.	T	Hydrogen-bonded Turn	trans	74	9.5	179.4	0	0	0	0	0	114.7	L107 E166	G105-L107 VanDerWaalsContact C-N 3.3Å; G105-L107 PolarHBondContact O-N 3.37Å; G105-E166 WeakPolarHBondContact CA-OE2 3.48Å; G105-E166 PolarHBondContact N-OE1 2.93Å; G105-E166 PolarHBondContact N-OE2 2.74Å
106	C	88	Confident	93.4	Very high	4 Å²	4	50.9 Å²	50.9	3%	0.027	26%	0.264	C	S	.	.			trans	-74.9	-20.2	-178.3	64.5	0	0	0	0	113.3	Y99 S103 R104 T108 T111	Y99-C106 HydrophobicContact CE1-CB 3.71Å; S103-C106 PolarHBondContact O-SG 3.28Å; S103-C106 VanDerWaalsContact O-SG 3.39Å; R104-C106 VanDerWaalsContact C-N 3.26Å; R104-C106 PolarHBondContact O-N 3.47Å; C106-T108 PolarHBondContact O-N 3.32Å; C106-T111 PolarHBondContact O-OG1 2.95Å
107	L	92.2	Very high	93.4	Very high	14 Å²	14	55.2 Å²	55.2	7%	0.073	28%	0.28	C	S	.	.			trans	-90.4	74.2	-177.7	-58.6	-170.4	0	0	0	112.2	I100 G105 T111 Y112 F161 E166	I100-L107 HydrophobicContact CD1-CD2 4.04Å; I100-L107 HydrophobicContact CG1-CD2 4.38Å; G105-L107 VanDerWaalsContact C-N 3.3Å; G105-L107 PolarHBondContact O-N 3.37Å; L107-T111 HydrophobicContact CD2-CG2 4.07Å; L107-Y112 HydrophobicContact CB-CE2 4.43Å; L107-F161 HydrophobicContact CD1-CD2 4.17Å; L107-F161 HydrophobicContact CD1-CE2 4.34Å; L107-F161 HydrophobicContact CD2-CD2 3.77Å; L107-F161 HydrophobicContact CD2-CE2 3.95Å; L107-E166 HydrophobicContact CD1-CB 4.31Å
108	T	91.4	Very high	93.4	Very high	56 Å²	56	55 Å²	55	34%	0.344	28%	0.279	S	S	.	.			trans	-79.9	165.4	171.7	74.3	0	0	0	0	111.7	C106 Q110 T111 Y112	C106-T108 PolarHBondContact O-N 3.32Å; T108-Q110 PolarHBondContact O-N 2.97Å; T108-Q110 VanDerWaalsContact O-N 3.17Å; T108-Q110 PolarHBondContact OG1-N 3.19Å; T108-T111 PolarHBondContact N-OG1 3.48Å; T108-T111 VanDerWaalsContact O-CB 3.26Å; T108-T111 WeakPolarHBondContact O-CB 3.48Å; T108-T111 PolarHBondContact O-N 2.88Å; T108-T111 PolarHBondContact O-OG1 2.92Å; T108-T111 PolarHBondContact OG1-N 3.34Å; T108-T111 PolarHBondContact OG1-OG1 3.24Å; T108-Y112 WeakPolarHBondContact O-CD2 3.36Å
109	E	92.2	Very high	93.5	Very high	130 Å²	130	51.2 Å²	51.2	61%	0.607	26%	0.259	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.8	-32.9	175.8	-68	-160.3	158.1	0	0	113.4	T111 P113 I171	E109-T111 VanDerWaalsContact C-N 3.31Å; E109-P113 VanDerWaalsContact O-CD 3.3Å; E109-P113 WeakPolarHBondContact O-CD 3.39Å; E109-I171 HydrophobicContact CG-CD1 3.85Å; E109-I171 HydrophobicContact CG-CG1 4.49Å
110	Q	93.4	Very high	93.6	Very high	136 Å²	136	51.5 Å²	51.5	64%	0.636	26%	0.264	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.3	-23.5	178.4	-62.4	-179.6	7	0	0	112.7	L64 T108 P113	L64-Q110 HydrophobicContact CD1-CB 4.43Å; T108-Q110 PolarHBondContact O-N 2.97Å; T108-Q110 VanDerWaalsContact O-N 3.17Å; T108-Q110 PolarHBondContact OG1-N 3.19Å; Q110-P113 WeakPolarHBondContact O-CD 3.31Å; Q110-P113 WeakPolarHBondContact O-CG 3.47Å
111	T	95.1	Very high	93.6	Very high	4 Å²	4	53.5 Å²	53.5	3%	0.025	28%	0.278	C	S	.	.	H	α-helix	trans	-69.1	-39.1	-179.8	-54.3	0	0	0	0	112	F63 C106 L107 T108 E109 E114 V115	F63-T111 HydrophobicContact CD1-CG2 4.21Å; F63-T111 HydrophobicContact CE1-CG2 3.59Å; C106-T111 PolarHBondContact O-OG1 2.95Å; L107-T111 HydrophobicContact CD2-CG2 4.07Å; T108-T111 PolarHBondContact N-OG1 3.48Å; T108-T111 VanDerWaalsContact O-CB 3.26Å; T108-T111 WeakPolarHBondContact O-CB 3.48Å; T108-T111 PolarHBondContact O-N 2.88Å; T108-T111 PolarHBondContact O-OG1 2.92Å; T108-T111 PolarHBondContact OG1-N 3.34Å; T108-T111 PolarHBondContact OG1-OG1 3.24Å; E109-T111 VanDerWaalsContact C-N 3.31Å; T111-E114 PolarHBondContact O-N 3.05Å; T111-V115 HydrophobicContact CG2-CG2 3.86Å; T111-V115 WeakPolarHBondContact O-CG2 2.93Å; T111-V115 PolarHBondContact O-N 3.12Å
112	Y	96.9	Very high	93.8	Very high	0 Å²	0	50.5 Å²	50.5	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-55.8	-53.4	-175.9	-73.4	-97.9	0	0	0	114.4	L107 T108 E114 V115 V116 F161 F167 Q168 I171 A172	L107-Y112 HydrophobicContact CB-CE2 4.43Å; T108-Y112 WeakPolarHBondContact O-CD2 3.36Å; Y112-E114 VanDerWaalsContact C-N 3.31Å; Y112-E114 PolarHBondContact O-N 2.75Å; Y112-V115 PolarHBondContact O-N 3.37Å; Y112-V116 WeakPolarHBondContact O-CG2 3.38Å; Y112-V116 PolarHBondContact O-N 3.39Å; Y112-F161 HydrophobicContact CD1-CE2 4.11Å; Y112-F161 AromaticContact CD1-CZ 3.55Å; Y112-F161 HydrophobicContact CD1-CZ 3.55Å; Y112-F161 HydrophobicContact CE1-CE2 4.04Å; Y112-F161 AromaticContact CE1-CZ 3.74Å; Y112-F161 HydrophobicContact CE1-CZ 3.74Å; Y112-F161 HydrophobicContact CG-CZ 4.3Å; Y112-F167 AromaticContact CE1-CD2 3.97Å; Y112-F167 HydrophobicContact CE1-CD2 3.97Å; Y112-F167 AromaticContact CE1-CE2 3.86Å; Y112-F167 HydrophobicContact CE1-CE2 3.86Å; Y112-Q168 PolarHBondContact OH-N 2.87Å; Y112-I171 HydrophobicContact CD1-CG2 4.24Å; Y112-I171 HydrophobicContact CD2-CB 4.4Å; Y112-I171 HydrophobicContact CD2-CG2 3.67Å; Y112-I171 HydrophobicContact CE2-CB 4.41Å; Y112-I171 HydrophobicContact CE2-CD1 4.32Å; Y112-I171 HydrophobicContact CE2-CG2 4.13Å; Y112-I171 HydrophobicContact CG-CG2 3.76Å; Y112-A172 HydrophobicContact CD1-CB 3.67Å; Y112-A172 HydrophobicContact CE1-CB 3.78Å
113	P	96.8	Very high	94.1	Very high	37 Å²	37	44 Å²	44	24%	0.24	23%	0.226	C	C	.	.	H	α-helix	trans	-61.4	-39.1	179.3	20.9	-31.3	0	0	0	112.4	E109 Q110 V116 R117 Y175	E109-P113 VanDerWaalsContact O-CD 3.3Å; E109-P113 WeakPolarHBondContact O-CD 3.39Å; Q110-P113 WeakPolarHBondContact O-CD 3.31Å; Q110-P113 WeakPolarHBondContact O-CG 3.47Å; P113-V116 PolarHBondContact O-N 3.49Å; P113-R117 WeakPolarHBondContact O-CB 3.3Å; P113-R117 PolarHBondContact O-N 2.69Å; P113-Y175 HydrophobicContact CB-CD1 4.06Å; P113-Y175 HydrophobicContact CB-CE1 3.64Å; P113-Y175 HydrophobicContact CB-CE2 4.38Å; P113-Y175 HydrophobicContact CG-CE1 4.3Å; P113-Y175 HydrophobicContact CG-CE2 4.44Å
114	E	97	Very high	94.5	Very high	39 Å²	39	43.5 Å²	43.5	18%	0.182	22%	0.22	C	C	.	.	H	α-helix	trans	-68.6	-39.9	-179.4	-67.9	-55.8	142.3	0	0	112.3	L64 L67 Q68 T111 Y112 R117 M118	L64-E114 HydrophobicContact CD2-CB 4.13Å; L64-E114 HydrophobicContact CD2-CG 4.01Å; L67-E114 HydrophobicContact CB-CB 4.46Å; L67-E114 HydrophobicContact CD1-CB 4.07Å; Q68-E114 WeakPolarHBondContact CG-OE2 3.37Å; T111-E114 PolarHBondContact O-N 3.05Å; Y112-E114 VanDerWaalsContact C-N 3.31Å; Y112-E114 PolarHBondContact O-N 2.75Å; E114-R117 PolarHBondContact O-N 2.77Å; E114-R117 IonicContact OE1-NE 2.75Å; E114-R117 IonicContact OE2-CZ 3.1Å; E114-R117 VanDerWaalsContact OE2-CZ 3.29Å; E114-R117 IonicContact OE2-NE 3.46Å; E114-R117 PolarHBondContact OE2-NE 3.41Å; E114-R117 IonicContact OE2-NH2 3.14Å; E114-R117 PolarHBondContact OE2-NH2 3.29Å; E114-M118 VanDerWaalsContact O-CB 3.28Å; E114-M118 WeakPolarHBondContact O-CB 3.43Å; E114-M118 PolarHBondContact O-N 2.8Å
115	V	97.5	Very high	94.9	Very high	0 Å²	0	33.4 Å²	33.4	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-61.8	-51.3	173.2	165.9	0	0	0	0	110.8	L67 T111 Y112 R117 M118 V119 F157 F158 F161	L67-V115 HydrophobicContact CD1-CG2 3.78Å; L67-V115 HydrophobicContact CD2-CG2 4.35Å; T111-V115 HydrophobicContact CG2-CG2 3.86Å; T111-V115 WeakPolarHBondContact O-CG2 2.93Å; T111-V115 PolarHBondContact O-N 3.12Å; Y112-V115 PolarHBondContact O-N 3.37Å; V115-R117 VanDerWaalsContact C-N 3.3Å; V115-R117 PolarHBondContact O-N 2.92Å; V115-M118 PolarHBondContact O-N 3.42Å; V115-V119 HydrophobicContact CG1-CG2 4.47Å; V115-V119 WeakPolarHBondContact O-CG2 3.42Å; V115-V119 PolarHBondContact O-N 3.41Å; V115-F157 HydrophobicContact CB-CE1 4.36Å; V115-F157 HydrophobicContact CG1-CE1 3.81Å; V115-F157 HydrophobicContact CG2-CE1 3.89Å; V115-F157 HydrophobicContact CG2-CZ 3.9Å; V115-F158 HydrophobicContact CG1-CD2 4.39Å; V115-F161 HydrophobicContact CB-CE2 4.37Å; V115-F161 HydrophobicContact CB-CZ 4.33Å; V115-F161 HydrophobicContact CG1-CB 4.48Å; V115-F161 HydrophobicContact CG1-CD1 3.7Å; V115-F161 HydrophobicContact CG1-CD2 4.04Å; V115-F161 HydrophobicContact CG1-CE1 3.73Å; V115-F161 HydrophobicContact CG1-CE2 4.11Å; V115-F161 HydrophobicContact CG1-CG 3.82Å; V115-F161 HydrophobicContact CG1-CZ 3.94Å; V115-F161 HydrophobicContact CG2-CD2 4.39Å; V115-F161 HydrophobicContact CG2-CE2 4.35Å
116	V	97.3	Very high	95.1	Very high	10 Å²	10	35.8 Å²	35.8	6%	0.061	19%	0.186	C	C	.	.	H	α-helix	trans	-62.5	-39.9	-179	173.8	0	0	0	0	110.8	Y112 P113 S120 I176 F180	Y112-V116 WeakPolarHBondContact O-CG2 3.38Å; Y112-V116 PolarHBondContact O-N 3.39Å; P113-V116 PolarHBondContact O-N 3.49Å; V116-S120 WeakPolarHBondContact O-CB 3.34Å; V116-S120 PolarHBondContact O-N 3.47Å; V116-S120 PolarHBondContact O-OG 2.96Å; V116-I176 HydrophobicContact CG2-CD1 4.46Å; V116-I176 HydrophobicContact CG2-CG1 4Å; V116-F180 HydrophobicContact CG1-CD2 3.95Å; V116-F180 HydrophobicContact CG1-CE2 3.89Å
117	R	97.3	Very high	95.2	Very high	92 Å²	92	37.3 Å²	37.3	35%	0.347	19%	0.194	S	C	.	.	H	α-helix	trans	-63.2	-47	175.5	-170	-179.4	67.6	65.5	18.3	111.5	Q68 C71 P113 E114 V115 S120 C121	Q68-R117 VanDerWaalsContact CG-NH2 3.33Å; C71-R117 PolarHBondContact SG-NH1 3.45Å; C71-R117 PolarHBondContact SG-NH2 2.88Å; P113-R117 WeakPolarHBondContact O-CB 3.3Å; P113-R117 PolarHBondContact O-N 2.69Å; E114-R117 PolarHBondContact O-N 2.77Å; E114-R117 IonicContact OE1-NE 2.75Å; E114-R117 IonicContact OE2-CZ 3.1Å; E114-R117 VanDerWaalsContact OE2-CZ 3.29Å; E114-R117 IonicContact OE2-NE 3.46Å; E114-R117 PolarHBondContact OE2-NE 3.41Å; E114-R117 IonicContact OE2-NH2 3.14Å; E114-R117 PolarHBondContact OE2-NH2 3.29Å; V115-R117 VanDerWaalsContact C-N 3.3Å; V115-R117 PolarHBondContact O-N 2.92Å; R117-S120 PolarHBondContact O-N 3.03Å; R117-C121 WeakPolarHBondContact O-CB 3.44Å; R117-C121 PolarHBondContact O-N 2.65Å; R117-C121 PolarHBondContact O-SG 2.87Å
118	M	97.6	Very high	94.8	Very high	0 Å²	0	38.7 Å²	38.7	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-59.2	-48.9	177.8	-173.6	-77.1	-72.2	0	0	111.6	L67 C70 C71 L93 E114 V115 N122 V154 F157	L67-M118 HydrophobicContact CD2-CB 4.4Å; L67-M118 HydrophobicContact CD2-CE 3.92Å; L67-M118 HydrophobicContact CD2-CG 4.32Å; L67-M118 WeakPolarHBondContact O-CG 3.38Å; C70-M118 HydrophobicContact CB-CG 3.83Å; C70-M118 HydrophobicContact CB-SD 4.29Å; C71-M118 VanDerWaalsContact SG-CA 3.54Å; L93-M118 HydrophobicContact CD2-SD 4.28Å; E114-M118 VanDerWaalsContact O-CB 3.28Å; E114-M118 WeakPolarHBondContact O-CB 3.43Å; E114-M118 PolarHBondContact O-N 2.8Å; V115-M118 PolarHBondContact O-N 3.42Å; M118-N122 PolarHBondContact O-N 3.16Å; M118-N122 PolarHBondContact O-ND2 3.14Å; M118-V154 HydrophobicContact SD-CG1 4.21Å; M118-V154 HydrophobicContact SD-CG2 4.15Å; M118-F157 HydrophobicContact CE-CD1 3.35Å; M118-F157 HydrophobicContact CE-CE1 3.54Å; M118-F157 HydrophobicContact CE-CG 4.15Å; M118-F157 HydrophobicContact CE-CZ 4.47Å
119	V	97.9	Very high	94.1	Very high	0 Å²	0	40 Å²	40	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-61	-51.1	177	172.5	0	0	0	0	110.5	V115 C121 N122 I123 V154 F158	V115-V119 HydrophobicContact CG1-CG2 4.47Å; V115-V119 WeakPolarHBondContact O-CG2 3.42Å; V115-V119 PolarHBondContact O-N 3.41Å; V119-C121 PolarHBondContact O-N 2.87Å; V119-N122 PolarHBondContact O-N 3.43Å; V119-N122 VanDerWaalsContact O-N 3.08Å; V119-I123 HydrophobicContact CG1-CD1 3.57Å; V119-I123 HydrophobicContact CG1-CG1 4.1Å; V119-I123 HydrophobicContact CG1-CG2 4.4Å; V119-I123 WeakPolarHBondContact O-CG1 3.09Å; V119-I123 PolarHBondContact O-N 3.2Å; V119-V154 HydrophobicContact CG2-CG1 4.26Å; V119-F158 HydrophobicContact CB-CD2 4.49Å; V119-F158 HydrophobicContact CG1-CB 4.44Å; V119-F158 HydrophobicContact CG1-CD1 4.01Å; V119-F158 HydrophobicContact CG1-CD2 4.36Å; V119-F158 HydrophobicContact CG1-CE1 4.3Å; V119-F158 HydrophobicContact CG1-CG 4.03Å; V119-F158 HydrophobicContact CG2-CB 3.85Å; V119-F158 HydrophobicContact CG2-CD2 3.74Å; V119-F158 HydrophobicContact CG2-CE2 4.45Å; V119-F158 HydrophobicContact CG2-CG 3.85Å
120	S	97.1	Very high	93.2	Very high	29 Å²	29	36.2 Å²	36.2	20%	0.203	20%	0.201	C	C	.	.	H	α-helix	trans	-58.8	-43.7	-177.1	-59.3	0	0	0	0	112.9	V116 R117 N122 F124	V116-S120 WeakPolarHBondContact O-CB 3.34Å; V116-S120 PolarHBondContact O-N 3.47Å; V116-S120 PolarHBondContact O-OG 2.96Å; R117-S120 PolarHBondContact O-N 3.03Å; S120-N122 PolarHBondContact O-N 3.17Å; S120-F124 WeakPolarHBondContact O-CB 3.08Å; S120-F124 PolarHBondContact O-N 3.2Å; S120-F124 WeakPolarHBondContact OG-CE2 3.32Å
121	C	95.7	Very high	91.5	Very high	50 Å²	50	35.3 Å²	35.3	34%	0.338	20%	0.201	S	C	.	.	H	α-helix	trans	-62.7	-31.9	178.4	-73.2	0	0	0	0	112.8	C71 I73 R117 V119	C71-C121 HydrophobicContact CB-CB 4.39Å; I73-C121 WeakPolarHBondContact CD1-O 3.48Å; R117-C121 WeakPolarHBondContact O-CB 3.44Å; R117-C121 PolarHBondContact O-N 2.65Å; R117-C121 PolarHBondContact O-SG 2.87Å; V119-C121 PolarHBondContact O-N 2.87Å
122	N	96.8	Very high	89.7	Confident	8 Å²	8	37.6 Å²	37.6	4%	0.043	22%	0.217	C	C	.	.	H	α-helix	trans	-88.2	-43.3	-176.6	-78	-85.3	0	0	0	112.8	C70 I73 K89 M118 V119 S120 L151 V154	C70-N122 PolarHBondContact O-ND2 2.92Å; I73-N122 HydrophobicContact CD1-CB 4.26Å; I73-N122 VanDerWaalsContact CD1-OD1 3.23Å; I73-N122 WeakPolarHBondContact CD1-OD1 3.19Å; K89-N122 PolarHBondContact NZ-OD1 3.24Å; M118-N122 PolarHBondContact O-N 3.16Å; M118-N122 PolarHBondContact O-ND2 3.14Å; V119-N122 PolarHBondContact O-N 3.43Å; V119-N122 VanDerWaalsContact O-N 3.08Å; S120-N122 PolarHBondContact O-N 3.17Å; N122-L151 HydrophobicContact CB-CD2 4.46Å; N122-L151 WeakPolarHBondContact O-CD2 3.35Å; N122-V154 HydrophobicContact CB-CB 4.49Å; N122-V154 HydrophobicContact CB-CG1 4.01Å; N122-V154 HydrophobicContact CB-CG2 3.98Å
123	I	96.5	Very high	87.9	Confident	0 Å²	0	46.2 Å²	46.2	0%	0	26%	0.263	C	S	.	.	H	α-helix	trans	-90.9	-38.9	-171.1	73.6	176.1	0	0	0	113	V119 R125 L151 V154 Y155 L184 L187	V119-I123 HydrophobicContact CG1-CD1 3.57Å; V119-I123 HydrophobicContact CG1-CG1 4.1Å; V119-I123 HydrophobicContact CG1-CG2 4.4Å; V119-I123 WeakPolarHBondContact O-CG1 3.09Å; V119-I123 PolarHBondContact O-N 3.2Å; I123-R125 PolarHBondContact O-N 3Å; I123-R125 PolarHBondContact O-NH1 3.37Å; I123-L151 HydrophobicContact CG2-CD2 4.45Å; I123-V154 HydrophobicContact CG2-CG1 3.87Å; I123-Y155 HydrophobicContact CB-CE1 4.5Å; I123-Y155 HydrophobicContact CD1-CE1 4.28Å; I123-Y155 HydrophobicContact CG2-CE1 4.02Å; I123-Y155 HydrophobicContact CG2-CE2 4.2Å; I123-L184 HydrophobicContact CD1-CD1 3.94Å; I123-L187 HydrophobicContact CB-CD1 4Å; I123-L187 HydrophobicContact CD1-CD1 4.19Å; I123-L187 HydrophobicContact CG1-CD1 3.99Å; I123-L187 WeakPolarHBondContact O-CD1 3.5Å; I123-L187 WeakPolarHBondContact O-CD2 3.28Å
124	F	96.4	Very high	86.2	Confident	21 Å²	21	53.1 Å²	53.1	9%	0.092	29%	0.292	C	S	.	.			trans	-79.6	96.8	-171.4	-62.2	-36.1	0	0	0	111.2	Q35 S120 F180 Q183 L184 L187	Q35-F124 PolarHBondContact NE2-O 3.13Å; S120-F124 WeakPolarHBondContact O-CB 3.08Å; S120-F124 PolarHBondContact O-N 3.2Å; S120-F124 WeakPolarHBondContact OG-CE2 3.32Å; F124-F180 AromaticContact CE2-CD2 3.56Å; F124-F180 HydrophobicContact CE2-CD2 3.56Å; F124-F180 AromaticContact CE2-CE2 3.59Å; F124-F180 HydrophobicContact CE2-CE2 3.59Å; F124-F180 HydrophobicContact CE2-CG 4.24Å; F124-F180 HydrophobicContact CE2-CZ 4.31Å; F124-F180 HydrophobicContact CZ-CD1 4.18Å; F124-F180 AromaticContact CZ-CD2 3.6Å; F124-F180 HydrophobicContact CZ-CD2 3.6Å; F124-F180 HydrophobicContact CZ-CE1 4.08Å; F124-F180 AromaticContact CZ-CE2 3.48Å; F124-F180 HydrophobicContact CZ-CE2 3.48Å; F124-F180 VanDerWaalsContact CZ-CE2 3.48Å; F124-F180 AromaticContact CZ-CG 3.95Å; F124-F180 HydrophobicContact CZ-CG 3.95Å; F124-F180 AromaticContact CZ-CZ 3.73Å; F124-F180 HydrophobicContact CZ-CZ 3.73Å; F124-Q183 HydrophobicContact CD1-CB 3.61Å; F124-Q183 HydrophobicContact CD2-CB 4.13Å; F124-Q183 HydrophobicContact CE1-CB 3.76Å; F124-Q183 HydrophobicContact CE2-CB 4.22Å; F124-Q183 HydrophobicContact CG-CB 3.85Å; F124-Q183 HydrophobicContact CZ-CB 4.06Å; F124-L184 HydrophobicContact CE1-CB 4.01Å; F124-L184 HydrophobicContact CE1-CD1 4.27Å; F124-L184 HydrophobicContact CZ-CB 4.47Å; F124-L187 HydrophobicContact CD1-CD1 3.87Å; F124-L187 HydrophobicContact CE1-CD1 4.27Å
125	R	93.7	Very high	84.4	Confident	21 Å²	21	53.7 Å²	53.7	8%	0.079	29%	0.294	C	S	.	.			trans	-134.8	157.4	178.8	68.8	-164.6	-176.9	-67	-2.6	110.1	Q35 I123 L127 E145 E195	Q35-R125 VanDerWaalsContact CD-CB 3.47Å; Q35-R125 HydrophobicContact CG-CB 4.06Å; I123-R125 PolarHBondContact O-N 3Å; I123-R125 PolarHBondContact O-NH1 3.37Å; R125-L127 PolarHBondContact O-N 2.71Å; R125-E145 IonicContact CZ-OE2 3.59Å; R125-E145 IonicContact NE-OE2 3.2Å; R125-E145 PolarHBondContact NE-OE2 2.87Å; R125-E145 VanDerWaalsContact NE-OE2 3.12Å; R125-E145 IonicContact NH2-OE2 3.06Å; R125-E145 PolarHBondContact NH2-OE2 3.35Å; R125-E195 IonicContact CZ-OE1 2.75Å; R125-E195 IonicContact CZ-OE2 2.77Å; R125-E195 IonicContact NH1-OE1 3.15Å; R125-E195 PolarHBondContact NH1-OE1 3.34Å; R125-E195 IonicContact NH1-OE2 2.68Å; R125-E195 VanDerWaalsContact NH2-CD 3.35Å; R125-E195 IonicContact NH2-OE1 2.66Å; R125-E195 PolarHBondContact NH2-OE1 3.1Å; R125-E195 VanDerWaalsContact NH2-OE1 3.09Å; R125-E195 IonicContact NH2-OE2 3.81Å; R125-E195 PolarHBondContact NH2-OE2 2.82Å
126	T	90.6	Very high	83.1	Confident	100 Å²	100	56.6 Å²	56.6	61%	0.613	31%	0.31	S	S	*	.	P	Polyproline II helix	trans	-69.5	124.6	165.1	-51.2	0	0	0	0	108.1
127	L	89.8	Confident	81.7	Confident	37 Å²	37	58.5 Å²	58.5	19%	0.194	32%	0.322	C	S	.	.	P	Polyproline II helix	trans	-64.4	145.8	175.2	-64	172.4	0	0	0	110	R125 L187 D189	R125-L127 PolarHBondContact O-N 2.71Å; L127-L187 HydrophobicContact CD2-CD2 4.29Å; L127-D189 VanDerWaalsContact CD1-C 3.43Å; L127-D189 HydrophobicContact CD1-CB 3.74Å
128	P	83.6	Confident	80.5	Confident	42 Å²	42	59 Å²	59	27%	0.273	33%	0.328	S	S	.	.	P	Polyproline II helix	trans	-60.6	150.5	175.6	27.6	-34.1	0	0	0	110.4	Q31	Q31-P128 HydrophobicContact CB-CB 4.49Å
129	P	77.8	Confident	79.4	Confident	83 Å²	83	66.6 Å²	66.6	54%	0.539	36%	0.364	S	S	.	.	P	Polyproline II helix	trans	-64.1	137.4	176.5	27.8	-33.7	0	0	0	110.5	D131	P129-D131 PolarHBondContact O-N 3.09Å
130	S	72.1	Confident	78.3	Confident	52 Å²	52	70 Å²	70	36%	0.364	38%	0.382	S	S	.	.	P	Polyproline II helix	trans	-67.1	126.2	172.5	-37.7	0	0	0	0	109.6	S132 H234	S130-S132 VanDerWaalsContact C-N 3.33Å; S130-S132 PolarHBondContact O-N 3.2Å; S130-H234 PolarHBondContact OG-NE2 2.9Å
131	D	57.9	Low	77.5	Confident	117 Å²	117	76.4 Å²	76.4	63%	0.626	41%	0.409	S	S	*	.	S	Bend	trans	-85.8	14.5	-165.9	-99.8	-17.5	0	0	0	115.1	Q31 P129	Q31-D131 VanDerWaalsContact NE2-CG 3.29Å; Q31-D131 PolarHBondContact NE2-OD1 3.22Å; Q31-D131 PolarHBondContact NE2-OD2 3.37Å; P129-D131 PolarHBondContact O-N 3.09Å
132	S	57.4	Low	76.9	Confident	51 Å²	51	77 Å²	77	36%	0.357	41%	0.412	S	S	.	.			trans	-153.3	132.6	173.3	58	0	0	0	0	115.8	S130 E134 F135	S130-S132 VanDerWaalsContact C-N 3.33Å; S130-S132 PolarHBondContact O-N 3.2Å; S132-E134 PolarHBondContact O-N 2.89Å; S132-F135 PolarHBondContact O-N 3.19Å; S132-F135 VanDerWaalsContact OG-CA 3.31Å; S132-F135 WeakPolarHBondContact OG-CA 3.35Å; S132-F135 VanDerWaalsContact OG-CB 3.25Å; S132-F135 WeakPolarHBondContact OG-CB 3.38Å; S132-F135 PolarHBondContact OG-N 3.35Å
133	N	58.2	Low	76.2	Confident	181 Å²	181	79.7 Å²	79.7	97%	0.968	43%	0.429	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.1	-8.8	165.5	-70.2	-17.7	0	0	0	113.3
134	E	61.3	Low	75.9	Confident	182 Å²	182	84.2 Å²	84.2	85%	0.85	45%	0.452	S	S	*	.	T	Hydrogen-bonded Turn	trans	-115.6	19.4	179.9	-65.5	-176.3	167	0	0	111.7	S132 D136	S132-E134 PolarHBondContact O-N 2.89Å; E134-D136 PolarHBondContact O-N 3.08Å; E134-D136 VanDerWaalsContact O-N 3.15Å
135	F	59.7	Low	75.6	Confident	51 Å²	51	84.5 Å²	84.5	22%	0.224	45%	0.454	C	S	.	.			trans	-56	121.3	179.3	-172.7	-108.5	0	0	0	109.6	S132 P137 D140	S132-F135 PolarHBondContact O-N 3.19Å; S132-F135 VanDerWaalsContact OG-CA 3.31Å; S132-F135 WeakPolarHBondContact OG-CA 3.35Å; S132-F135 VanDerWaalsContact OG-CB 3.25Å; S132-F135 WeakPolarHBondContact OG-CB 3.38Å; S132-F135 PolarHBondContact OG-N 3.35Å; F135-P137 HydrophobicContact CD1-CB 4.16Å; F135-P137 HydrophobicContact CD1-CG 3.8Å; F135-P137 VanDerWaalsContact CE1-CA 3.43Å; F135-P137 HydrophobicContact CE1-CB 3.71Å; F135-P137 HydrophobicContact CE1-CG 3.87Å; F135-P137 WeakPolarHBondContact O-CD 3.23Å; F135-D140 VanDerWaalsContact CA-OD2 3.3Å; F135-D140 WeakPolarHBondContact CA-OD2 3.4Å; F135-D140 HydrophobicContact CD2-CB 3.58Å; F135-D140 WeakPolarHBondContact CD2-OD2 3.4Å; F135-D140 HydrophobicContact CE2-CB 3.19Å; F135-D140 HydrophobicContact CZ-CB 3.86Å
136	D	70.6	Confident	75.5	Confident	62 Å²	62	85.2 Å²	85.2	33%	0.332	47%	0.465	S	S	.	.			trans	-99.1	103.8	167.2	-170.5	-18.4	0	0	0	107.4	E134 E138 E139 D140	E134-D136 PolarHBondContact O-N 3.08Å; E134-D136 VanDerWaalsContact O-N 3.15Å; D136-E138 PolarHBondContact O-N 3.11Å; D136-E138 WeakPolarHBondContact OD1-CB 3.34Å; D136-E138 PolarHBondContact OD1-N 2.97Å; D136-E139 HydrophobicContact CB-CB 4.22Å; D136-E139 HydrophobicContact CB-CG 4.46Å; D136-E139 PolarHBondContact O-N 2.88Å; D136-D140 PolarHBondContact N-OD2 3.37Å; D136-D140 WeakPolarHBondContact O-CB 3.43Å; D136-D140 PolarHBondContact O-N 2.79Å
137	P	68	Low	75.6	Confident	50 Å²	50	81 Å²	81	33%	0.325	44%	0.439	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.5	-16.2	-178	-15.6	26.9	0	0	0	113.9	F135 L279	F135-P137 HydrophobicContact CD1-CB 4.16Å; F135-P137 HydrophobicContact CD1-CG 3.8Å; F135-P137 VanDerWaalsContact CE1-CA 3.43Å; F135-P137 HydrophobicContact CE1-CB 3.71Å; F135-P137 HydrophobicContact CE1-CG 3.87Å; F135-P137 WeakPolarHBondContact O-CD 3.23Å; P137-L279 HydrophobicContact CB-CD1 3.39Å; P137-L279 HydrophobicContact CB-CD2 4.2Å; P137-L279 HydrophobicContact CB-CG 4.38Å; P137-L279 HydrophobicContact CG-CD1 3.88Å
138	E	71	Confident	75.9	Confident	102 Å²	102	80.1 Å²	80.1	48%	0.477	43%	0.433	S	S	.	.	T	Hydrogen-bonded Turn	trans	-81.7	-29.9	175.2	-65.5	-173.4	-154	0	0	112.7	D136 S278 L279	D136-E138 PolarHBondContact O-N 3.11Å; D136-E138 WeakPolarHBondContact OD1-CB 3.34Å; D136-E138 PolarHBondContact OD1-N 2.97Å; E138-S278 WeakPolarHBondContact OE1-CB 3.2Å; E138-S278 PolarHBondContact OE1-OG 3.41Å; E138-L279 HydrophobicContact CG-CD2 3.87Å
139	E	76.2	Confident	76.5	Confident	160 Å²	160	80.9 Å²	80.9	75%	0.748	44%	0.438	S	S	*	.	T	Hydrogen-bonded Turn	trans	-105.1	-31.1	-173.7	-62.7	-166.2	166.7	0	0	113.7	D136	D136-E139 HydrophobicContact CB-CB 4.22Å; D136-E139 HydrophobicContact CB-CG 4.46Å; D136-E139 PolarHBondContact O-N 2.88Å
140	D	74.8	Confident	77.4	Confident	70 Å²	70	77.2 Å²	77.2	37%	0.374	41%	0.414	S	S	.	.	S	Bend	trans	-81.1	136.5	-171.4	-72.8	-41.3	0	0	0	112.9	F135 D136	F135-D140 VanDerWaalsContact CA-OD2 3.3Å; F135-D140 WeakPolarHBondContact CA-OD2 3.4Å; F135-D140 HydrophobicContact CD2-CB 3.58Å; F135-D140 WeakPolarHBondContact CD2-OD2 3.4Å; F135-D140 HydrophobicContact CE2-CB 3.19Å; F135-D140 HydrophobicContact CZ-CB 3.86Å; D136-D140 PolarHBondContact N-OD2 3.37Å; D136-D140 WeakPolarHBondContact O-CB 3.43Å; D136-D140 PolarHBondContact O-N 2.79Å
141	E	79.3	Confident	78.6	Confident	164 Å²	164	74.9 Å²	74.9	77%	0.766	40%	0.397	S	S	*	.	P	Polyproline II helix	trans	-69.8	130.8	175.8	-70.9	-176.5	178.1	0	0	110.7
142	P	82.2	Confident	80.5	Confident	64 Å²	64	72.9 Å²	72.9	42%	0.416	38%	0.384	S	S	.	.	P	Polyproline II helix	trans	-68.7	140.4	-177.3	27.4	-34.4	0	0	0	111.8	L144	P142-L144 PolarHBondContact O-N 3.35Å
143	T	83.8	Confident	82.4	Confident	63 Å²	63	71.2 Å²	71.2	39%	0.387	37%	0.371	S	S	.	.			trans	-72.3	115.5	172.2	-52.9	0	0	0	0	110.2	E191	T143-E191 WeakPolarHBondContact CB-OE2 3.18Å; T143-E191 PolarHBondContact N-OE2 3.08Å; T143-E191 VanDerWaalsContact N-OE2 3.1Å; T143-E191 PolarHBondContact OG1-OE2 3.36Å
144	L	90	Very high	84.4	Confident	95 Å²	95	62.6 Å²	62.6	50%	0.497	33%	0.325	S	S	.	.			trans	-79.7	141.5	177.2	-59.7	-176.4	0	0	0	111.7	P142 A146	P142-L144 PolarHBondContact O-N 3.35Å; L144-A146 PolarHBondContact O-N 2.95Å
145	E	89.6	Confident	86.1	Confident	28 Å²	28	54 Å²	54	13%	0.131	29%	0.285	C	S	.	.			trans	-73	122.8	179.5	175.1	52.5	-112.2	0	0	111.2	R125 S147 W148 L151 D192	R125-E145 IonicContact CZ-OE2 3.59Å; R125-E145 IonicContact NE-OE2 3.2Å; R125-E145 PolarHBondContact NE-OE2 2.87Å; R125-E145 VanDerWaalsContact NE-OE2 3.12Å; R125-E145 IonicContact NH2-OE2 3.06Å; R125-E145 PolarHBondContact NH2-OE2 3.35Å; E145-S147 VanDerWaalsContact C-N 3.29Å; E145-S147 VanDerWaalsContact CD-OG 3.31Å; E145-S147 PolarHBondContact O-N 2.89Å; E145-S147 PolarHBondContact OE1-N 2.65Å; E145-S147 PolarHBondContact OE1-OG 3.37Å; E145-W148 WeakPolarHBondContact O-CB 3.2Å; E145-W148 PolarHBondContact O-N 3.01Å; E145-L151 HydrophobicContact CG-CD1 3.49Å; E145-L151 VanDerWaalsContact CG-CD1 3.49Å; E145-D192 HydrophobicContact CB-CB 4.4Å; E145-D192 PolarHBondContact N-OD2 3.28Å
146	A	91.6	Very high	88	Confident	36 Å²	36	53.8 Å²	53.8	30%	0.298	29%	0.285	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.7	-32	-175.1	0	0	0	0	0	112.5	F76 M77 L144 W148	F76-A146 HydrophobicContact CB-CB 3.95Å; F76-A146 WeakPolarHBondContact CB-O 3.32Å; F76-A146 WeakPolarHBondContact CD1-O 3.46Å; M77-A146 HydrophobicContact SD-CB 4.03Å; L144-A146 PolarHBondContact O-N 2.95Å; A146-W148 PolarHBondContact O-N 3.37Å
147	S	93.6	Very high	89.3	Confident	11 Å²	11	50.9 Å²	50.9	8%	0.077	27%	0.269	C	S	.	.	T	Hydrogen-bonded Turn	trans	-83.5	8.3	178.7	63.2	0	0	0	0	114.3	F76 E145 P149 H150 L151	F76-S147 VanDerWaalsContact CD2-CB 3.48Å; E145-S147 VanDerWaalsContact C-N 3.29Å; E145-S147 VanDerWaalsContact CD-OG 3.31Å; E145-S147 PolarHBondContact O-N 2.89Å; E145-S147 PolarHBondContact OE1-N 2.65Å; E145-S147 PolarHBondContact OE1-OG 3.37Å; S147-P149 VanDerWaalsContact C-N 3.32Å; S147-P149 VanDerWaalsContact O-N 3.14Å; S147-H150 PolarHBondContact O-N 2.9Å; S147-L151 PolarHBondContact O-N 3.18Å; S147-L151 VanDerWaalsContact O-N 3.11Å; S147-L151 VanDerWaalsContact OG-CD1 3.3Å; S147-L151 WeakPolarHBondContact OG-CD1 3.37Å
148	W	95.8	Very high	90.7	Very high	19 Å²	19	48.5 Å²	48.5	7%	0.072	25%	0.253	C	S	.	.	H	α-helix	trans	-48	-40.3	-178.6	-169.9	-106.9	0	0	0	115.3	E145 A146 H150 L151 Q152 Y155 R194 E195 Y198	E145-W148 WeakPolarHBondContact O-CB 3.2Å; E145-W148 PolarHBondContact O-N 3.01Å; A146-W148 PolarHBondContact O-N 3.37Å; W148-H150 PolarHBondContact O-N 3.29Å; W148-H150 VanDerWaalsContact O-N 3.08Å; W148-L151 HydrophobicContact CE3-CB 4.27Å; W148-L151 PolarHBondContact O-N 2.97Å; W148-Q152 HydrophobicContact CD2-CB 4.35Å; W148-Q152 HydrophobicContact CZ2-CB 3.98Å; W148-Q152 HydrophobicContact CZ2-CG 4.13Å; W148-Q152 VanDerWaalsContact O-CB 3.32Å; W148-Q152 WeakPolarHBondContact O-CB 3.48Å; W148-Q152 PolarHBondContact O-N 3.18Å; W148-Y155 HydrophobicContact CZ3-CD2 4.5Å; W148-R194 VanDerWaalsContact CD1-NH1 3.26Å; W148-R194 VanDerWaalsContact CH2-C 3.48Å; W148-R194 HydrophobicContact CH2-CB 3.57Å; W148-R194 HydrophobicContact CZ2-CB 3.36Å; W148-R194 HydrophobicContact CZ2-CG 4.4Å; W148-R194 HydrophobicContact CZ3-CB 4.26Å; W148-E195 HydrophobicContact CH2-CB 4.42Å; W148-E195 HydrophobicContact CZ3-CB 3.79Å; W148-E195 HydrophobicContact CZ3-CG 4.4Å; W148-Y198 AromaticContact CH2-CD2 3.7Å; W148-Y198 HydrophobicContact CH2-CD2 3.7Å; W148-Y198 AromaticContact CH2-CE2 4Å; W148-Y198 HydrophobicContact CH2-CE2 4Å; W148-Y198 HydrophobicContact CZ2-CD2 4.02Å; W148-Y198 AromaticContact CZ2-CE2 3.84Å; W148-Y198 HydrophobicContact CZ2-CE2 3.84Å
149	P	95.2	Very high	92	Very high	58 Å²	58	44.4 Å²	44.4	38%	0.377	24%	0.235	S	C	.	.	H	α-helix	trans	-57.8	-25.6	178.2	-26.6	36.2	0	0	0	114.8	F76 S147	F76-P149 HydrophobicContact CE1-CG 4.39Å; S147-P149 VanDerWaalsContact C-N 3.32Å; S147-P149 VanDerWaalsContact O-N 3.14Å
150	H	97	Very high	93	Very high	6 Å²	6	40.9 Å²	40.9	3%	0.028	22%	0.215	C	C	.	.	H	α-helix	trans	-92.9	-45.3	172.1	-73.2	-176.1	0	0	0	111.4	F74 F76 K86 L93 S147 W148 Q152 L153 V154	F74-H150 AromaticContact CD2-CE1 3.8Å; F76-H150 HydrophobicContact CE2-CB 4.42Å; F76-H150 AromaticContact CE2-CE1 3.84Å; F76-H150 AromaticContact CE2-CG 3.9Å; F76-H150 AromaticContact CE2-ND1 3.51Å; F76-H150 HydrophobicContact CZ-CB 4.38Å; F76-H150 AromaticContact CZ-CD2 3.76Å; F76-H150 AromaticContact CZ-CE1 3.54Å; F76-H150 AromaticContact CZ-CG 3.64Å; F76-H150 AromaticContact CZ-ND1 3.54Å; F76-H150 AromaticContact CZ-NE2 3.7Å; K86-H150 PolarHBondContact O-CE1 3.2Å; K86-H150 PolarHBondContact O-NE2 3.02Å; L93-H150 HydrophobicContact CD1-CB 4.24Å; S147-H150 PolarHBondContact O-N 2.9Å; W148-H150 PolarHBondContact O-N 3.29Å; W148-H150 VanDerWaalsContact O-N 3.08Å; H150-Q152 VanDerWaalsContact C-N 3.33Å; H150-Q152 PolarHBondContact O-N 3.03Å; H150-L153 PolarHBondContact O-N 2.93Å; H150-V154 WeakPolarHBondContact O-CG2 3.33Å; H150-V154 PolarHBondContact O-N 3.32Å; H150-V154 VanDerWaalsContact O-N 3.1Å
151	L	97.2	Very high	94.1	Very high	3 Å²	3	37.6 Å²	37.6	2%	0.016	20%	0.197	C	C	.	.	H	α-helix	trans	-60.8	-40.6	-176.2	-68.2	-178.7	0	0	0	112.6	N122 I123 E145 S147 W148 L153 V154 Y155	N122-L151 HydrophobicContact CB-CD2 4.46Å; N122-L151 WeakPolarHBondContact O-CD2 3.35Å; I123-L151 HydrophobicContact CG2-CD2 4.45Å; E145-L151 HydrophobicContact CG-CD1 3.49Å; E145-L151 VanDerWaalsContact CG-CD1 3.49Å; S147-L151 PolarHBondContact O-N 3.18Å; S147-L151 VanDerWaalsContact O-N 3.11Å; S147-L151 VanDerWaalsContact OG-CD1 3.3Å; S147-L151 WeakPolarHBondContact OG-CD1 3.37Å; W148-L151 HydrophobicContact CE3-CB 4.27Å; W148-L151 PolarHBondContact O-N 2.97Å; L151-L153 VanDerWaalsContact C-N 3.29Å; L151-L153 PolarHBondContact O-N 3.36Å; L151-V154 PolarHBondContact O-N 3.02Å; L151-V154 VanDerWaalsContact O-N 3.12Å; L151-Y155 HydrophobicContact CB-CD2 4.4Å; L151-Y155 HydrophobicContact CB-CE2 4.36Å; L151-Y155 WeakPolarHBondContact O-CD2 3.17Å; L151-Y155 PolarHBondContact O-N 3.42Å
152	Q	98.1	Very high	95	Very high	74 Å²	74	29.8 Å²	29.8	35%	0.346	16%	0.16	S	C	.	.	H	α-helix	trans	-53.4	-47.9	176.9	-176.7	-178.7	-7.7	0	0	111.4	W148 H150 Y155 E156 Y198	W148-Q152 HydrophobicContact CD2-CB 4.35Å; W148-Q152 HydrophobicContact CZ2-CB 3.98Å; W148-Q152 HydrophobicContact CZ2-CG 4.13Å; W148-Q152 VanDerWaalsContact O-CB 3.32Å; W148-Q152 WeakPolarHBondContact O-CB 3.48Å; W148-Q152 PolarHBondContact O-N 3.18Å; H150-Q152 VanDerWaalsContact C-N 3.33Å; H150-Q152 PolarHBondContact O-N 3.03Å; Q152-Y155 PolarHBondContact O-N 2.81Å; Q152-E156 WeakPolarHBondContact O-CB 3.48Å; Q152-E156 PolarHBondContact O-N 2.66Å; Q152-Y198 HydrophobicContact CG-CE2 4.27Å
153	L	98.3	Very high	95.6	Very high	16 Å²	16	30.3 Å²	30.3	8%	0.084	16%	0.157	C	C	.	.	H	α-helix	trans	-69.8	-34.6	-179.6	-62.8	172.5	0	0	0	112.1	R90 L93 N94 H150 L151 F157	R90-L153 HydrophobicContact CG-CD1 3.74Å; R90-L153 WeakPolarHBondContact O-CD1 3.26Å; L93-L153 HydrophobicContact CB-CB 3.77Å; L93-L153 HydrophobicContact CB-CD1 3.79Å; L93-L153 HydrophobicContact CB-CG 4.43Å; L93-L153 HydrophobicContact CD1-CB 4.27Å; N94-L153 HydrophobicContact CB-CD1 4.47Å; H150-L153 PolarHBondContact O-N 2.93Å; L151-L153 VanDerWaalsContact C-N 3.29Å; L151-L153 PolarHBondContact O-N 3.36Å; L153-F157 WeakPolarHBondContact O-CB 3.24Å; L153-F157 PolarHBondContact O-N 2.95Å
154	V	98.5	Very high	96.2	Very high	0 Å²	0	28.5 Å²	28.5	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-64.4	-44.5	174.4	173.7	0	0	0	0	110.8	L93 M118 V119 N122 I123 H150 L151 F158	L93-V154 HydrophobicContact CD1-CG2 4.01Å; L93-V154 HydrophobicContact CD2-CG2 3.9Å; M118-V154 HydrophobicContact SD-CG1 4.21Å; M118-V154 HydrophobicContact SD-CG2 4.15Å; V119-V154 HydrophobicContact CG2-CG1 4.26Å; N122-V154 HydrophobicContact CB-CB 4.49Å; N122-V154 HydrophobicContact CB-CG1 4.01Å; N122-V154 HydrophobicContact CB-CG2 3.98Å; I123-V154 HydrophobicContact CG2-CG1 3.87Å; H150-V154 WeakPolarHBondContact O-CG2 3.33Å; H150-V154 PolarHBondContact O-N 3.32Å; H150-V154 VanDerWaalsContact O-N 3.1Å; L151-V154 PolarHBondContact O-N 3.02Å; L151-V154 VanDerWaalsContact O-N 3.12Å; V154-F158 WeakPolarHBondContact O-CB 3.44Å; V154-F158 PolarHBondContact O-N 3.12Å
155	Y	98.6	Very high	96.3	Very high	1 Å²	1	33.6 Å²	33.6	0%	0.004	17%	0.168	C	C	.	.	H	α-helix	trans	-65.8	-45	176.2	-79.2	-64.5	0	0	0	112.2	I123 W148 L151 Q152 F157 F158 I159 E195 Y198 L199 V202	I123-Y155 HydrophobicContact CB-CE1 4.5Å; I123-Y155 HydrophobicContact CD1-CE1 4.28Å; I123-Y155 HydrophobicContact CG2-CE1 4.02Å; I123-Y155 HydrophobicContact CG2-CE2 4.2Å; W148-Y155 HydrophobicContact CZ3-CD2 4.5Å; L151-Y155 HydrophobicContact CB-CD2 4.4Å; L151-Y155 HydrophobicContact CB-CE2 4.36Å; L151-Y155 WeakPolarHBondContact O-CD2 3.17Å; L151-Y155 PolarHBondContact O-N 3.42Å; Q152-Y155 PolarHBondContact O-N 2.81Å; Y155-F157 PolarHBondContact O-N 3.27Å; Y155-F158 PolarHBondContact O-N 3.09Å; Y155-I159 WeakPolarHBondContact O-CG1 3.45Å; Y155-I159 PolarHBondContact O-N 2.69Å; Y155-E195 HydrophobicContact CE2-CG 3.81Å; Y155-E195 WeakPolarHBondContact OH-CG 3.35Å; Y155-E195 PolarHBondContact OH-OE1 3.39Å; Y155-Y198 HydrophobicContact CD2-CG 4.48Å; Y155-Y198 HydrophobicContact CG-CD1 4.26Å; Y155-Y198 HydrophobicContact CG-CG 4.09Å; Y155-L199 HydrophobicContact CE1-CD2 3.8Å; Y155-L199 HydrophobicContact CE1-CG 4.19Å; Y155-V202 HydrophobicContact CD1-CG2 4.38Å
156	E	98.1	Very high	96.5	Very high	48 Å²	48	35.5 Å²	35.5	22%	0.224	18%	0.177	C	C	.	.	H	α-helix	trans	-59.9	-46.4	176.3	-176	171	-176.9	0	0	111.3	V97 Q152 F158 I159 R160 Y198	V97-E156 HydrophobicContact CG1-CG 3.9Å; V97-E156 HydrophobicContact CG2-CB 4.48Å; V97-E156 HydrophobicContact CG2-CG 4.44Å; Q152-E156 WeakPolarHBondContact O-CB 3.48Å; Q152-E156 PolarHBondContact O-N 2.66Å; E156-F158 VanDerWaalsContact C-N 3.3Å; E156-F158 PolarHBondContact O-N 3.03Å; E156-I159 PolarHBondContact O-N 3.31Å; E156-R160 VanDerWaalsContact O-CG 3.32Å; E156-R160 WeakPolarHBondContact O-CG 3.32Å; E156-R160 PolarHBondContact O-N 3.49Å; E156-R160 IonicContact OE1-CZ 3.38Å; E156-R160 IonicContact OE1-NH1 3.47Å; E156-R160 IonicContact OE1-NH2 3.97Å; E156-R160 PolarHBondContact OE1-NH2 2.9Å; E156-Y198 HydrophobicContact CB-CE1 4.3Å
157	F	98.4	Very high	96.7	Very high	0 Å²	0	34.5 Å²	34.5	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-56.1	-45.7	174.4	175.9	-96.6	0	0	0	111.5	F63 L67 L96 V97 I100 V115 M118 L153 Y155 R160 F161	F63-F157 HydrophobicContact CE2-CE2 4.13Å; F63-F157 HydrophobicContact CE2-CZ 4.4Å; F63-F157 AromaticContact CZ-CE2 3.93Å; F63-F157 HydrophobicContact CZ-CE2 3.93Å; F63-F157 AromaticContact CZ-CZ 3.86Å; F63-F157 HydrophobicContact CZ-CZ 3.86Å; L67-F157 HydrophobicContact CD2-CE1 3.91Å; L67-F157 HydrophobicContact CD2-CE2 4.46Å; L67-F157 HydrophobicContact CD2-CZ 3.67Å; L96-F157 HydrophobicContact CB-CD2 3.93Å; L96-F157 HydrophobicContact CB-CE2 3.94Å; V97-F157 HydrophobicContact CG2-CB 3.77Å; I100-F157 HydrophobicContact CB-CD2 4.43Å; I100-F157 HydrophobicContact CB-CE2 3.97Å; I100-F157 HydrophobicContact CD1-CD2 4.39Å; I100-F157 HydrophobicContact CD1-CE2 3.68Å; I100-F157 HydrophobicContact CD1-CZ 3.77Å; I100-F157 HydrophobicContact CG1-CE2 4.46Å; I100-F157 HydrophobicContact CG2-CD2 3.84Å; I100-F157 HydrophobicContact CG2-CE2 3.9Å; V115-F157 HydrophobicContact CB-CE1 4.36Å; V115-F157 HydrophobicContact CG1-CE1 3.81Å; V115-F157 HydrophobicContact CG2-CE1 3.89Å; V115-F157 HydrophobicContact CG2-CZ 3.9Å; M118-F157 HydrophobicContact CE-CD1 3.35Å; M118-F157 HydrophobicContact CE-CE1 3.54Å; M118-F157 HydrophobicContact CE-CG 4.15Å; M118-F157 HydrophobicContact CE-CZ 4.47Å; L153-F157 WeakPolarHBondContact O-CB 3.24Å; L153-F157 PolarHBondContact O-N 2.95Å; Y155-F157 PolarHBondContact O-N 3.27Å; F157-R160 PolarHBondContact O-N 2.98Å; F157-F161 WeakPolarHBondContact O-CB 3.2Å; F157-F161 PolarHBondContact O-N 2.74Å
158	F	98.3	Very high	96.8	Very high	0 Å²	0	38.4 Å²	38.4	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-68.5	-37.2	-178.6	-168.3	-135.4	0	0	0	112.7	V115 V119 V154 Y155 E156 F161 L162 I176 F180 V202 I206	V115-F158 HydrophobicContact CG1-CD2 4.39Å; V119-F158 HydrophobicContact CB-CD2 4.49Å; V119-F158 HydrophobicContact CG1-CB 4.44Å; V119-F158 HydrophobicContact CG1-CD1 4.01Å; V119-F158 HydrophobicContact CG1-CD2 4.36Å; V119-F158 HydrophobicContact CG1-CE1 4.3Å; V119-F158 HydrophobicContact CG1-CG 4.03Å; V119-F158 HydrophobicContact CG2-CB 3.85Å; V119-F158 HydrophobicContact CG2-CD2 3.74Å; V119-F158 HydrophobicContact CG2-CE2 4.45Å; V119-F158 HydrophobicContact CG2-CG 3.85Å; V154-F158 WeakPolarHBondContact O-CB 3.44Å; V154-F158 PolarHBondContact O-N 3.12Å; Y155-F158 PolarHBondContact O-N 3.09Å; E156-F158 VanDerWaalsContact C-N 3.3Å; E156-F158 PolarHBondContact O-N 3.03Å; F158-F161 AromaticContact CD2-CD1 3.71Å; F158-F161 HydrophobicContact CD2-CD1 3.71Å; F158-F161 HydrophobicContact CD2-CE1 4.4Å; F158-F161 AromaticContact CE2-CD1 3.7Å; F158-F161 HydrophobicContact CE2-CD1 3.7Å; F158-F161 AromaticContact CE2-CE1 3.98Å; F158-F161 HydrophobicContact CE2-CE1 3.98Å; F158-F161 WeakPolarHBondContact O-CB 3.21Å; F158-F161 PolarHBondContact O-N 3.1Å; F158-L162 HydrophobicContact CD1-CD1 4.06Å; F158-L162 HydrophobicContact CD2-CG 4.37Å; F158-L162 HydrophobicContact CE1-CD1 3.82Å; F158-L162 HydrophobicContact CE2-CD1 4.33Å; F158-L162 HydrophobicContact CE2-CD2 4.3Å; F158-L162 HydrophobicContact CE2-CG 4.15Å; F158-L162 HydrophobicContact CG-CD1 4.44Å; F158-L162 HydrophobicContact CZ-CD1 3.96Å; F158-L162 HydrophobicContact CZ-CD2 4.28Å; F158-L162 HydrophobicContact CZ-CG 4.22Å; F158-L162 WeakPolarHBondContact O-CB 3.11Å; F158-L162 VanDerWaalsContact O-CG 3.31Å; F158-L162 WeakPolarHBondContact O-CG 3.38Å; F158-L162 PolarHBondContact O-N 3.24Å; F158-I176 HydrophobicContact CE2-CD1 4.43Å; F158-I176 HydrophobicContact CZ-CD1 4.13Å; F158-F180 HydrophobicContact CE1-CE1 4.17Å; F158-F180 AromaticContact CE1-CZ 3.86Å; F158-F180 HydrophobicContact CE1-CZ 3.86Å; F158-F180 HydrophobicContact CZ-CE1 4.1Å; F158-F180 AromaticContact CZ-CZ 3.7Å; F158-F180 HydrophobicContact CZ-CZ 3.7Å; F158-V202 HydrophobicContact CD1-CG1 3.62Å; F158-V202 HydrophobicContact CD1-CG2 4.02Å; F158-V202 HydrophobicContact CE1-CG1 3.43Å; F158-V202 VanDerWaalsContact CE1-CG1 3.43Å; F158-I206 HydrophobicContact CE1-CD1 4.42Å
159	I	98.2	Very high	96.8	Very high	17 Å²	17	39.8 Å²	39.8	9%	0.087	20%	0.195	C	C	.	.	H	α-helix	trans	-61.8	-48.9	172.5	-70.8	174.5	0	0	0	110	Y155 E156 F161 L162 E163 Y198 T201 V202	Y155-I159 WeakPolarHBondContact O-CG1 3.45Å; Y155-I159 PolarHBondContact O-N 2.69Å; E156-I159 PolarHBondContact O-N 3.31Å; I159-F161 VanDerWaalsContact C-N 3.3Å; I159-F161 PolarHBondContact O-N 2.82Å; I159-L162 CarbonylContact O-C 3.58Å; I159-L162 PolarHBondContact O-N 3.37Å; I159-L162 VanDerWaalsContact O-N 3.12Å; I159-E163 HydrophobicContact CG2-CG 4.13Å; I159-E163 WeakPolarHBondContact O-CB 3.36Å; I159-E163 WeakPolarHBondContact O-CG 3.48Å; I159-E163 PolarHBondContact O-N 3.02Å; I159-Y198 HydrophobicContact CD1-CD1 3.52Å; I159-Y198 HydrophobicContact CD1-CE1 4.06Å; I159-T201 HydrophobicContact CD1-CG2 3.72Å; I159-T201 HydrophobicContact CG1-CG2 4.2Å; I159-T201 HydrophobicContact CG2-CG2 4.33Å; I159-V202 HydrophobicContact CD1-CG2 4.24Å; I159-V202 HydrophobicContact CG1-CG2 3.64Å
160	R	97.6	Very high	96.8	Very high	86 Å²	86	40.3 Å²	40.3	33%	0.325	20%	0.2	S	C	.	.	H	α-helix	trans	-61.1	-39.5	178.3	-64.2	-68.4	169.6	67	16	112	I100 T101 E156 F157 E163 S164	I100-R160 HydrophobicContact CG2-CB 3.82Å; T101-R160 PolarHBondContact OG1-NH1 3.28Å; T101-R160 VanDerWaalsContact OG1-NH1 3.07Å; E156-R160 VanDerWaalsContact O-CG 3.32Å; E156-R160 WeakPolarHBondContact O-CG 3.32Å; E156-R160 PolarHBondContact O-N 3.49Å; E156-R160 IonicContact OE1-CZ 3.38Å; E156-R160 IonicContact OE1-NH1 3.47Å; E156-R160 IonicContact OE1-NH2 3.97Å; E156-R160 PolarHBondContact OE1-NH2 2.9Å; F157-R160 PolarHBondContact O-N 2.98Å; R160-E163 PolarHBondContact O-N 3.4Å; R160-S164 PolarHBondContact O-N 3.41Å
161	F	97.3	Very high	96.8	Very high	0 Å²	0	40.6 Å²	40.6	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-58.7	-48.7	171.9	170	-110.3	0	0	0	112.3	I100 L107 Y112 V115 F157 F158 I159 E163 F167	I100-F161 HydrophobicContact CD1-CB 3.6Å; I100-F161 HydrophobicContact CD1-CD2 3.98Å; I100-F161 HydrophobicContact CD1-CG 4.28Å; L107-F161 HydrophobicContact CD1-CD2 4.17Å; L107-F161 HydrophobicContact CD1-CE2 4.34Å; L107-F161 HydrophobicContact CD2-CD2 3.77Å; L107-F161 HydrophobicContact CD2-CE2 3.95Å; Y112-F161 HydrophobicContact CD1-CE2 4.11Å; Y112-F161 AromaticContact CD1-CZ 3.55Å; Y112-F161 HydrophobicContact CD1-CZ 3.55Å; Y112-F161 HydrophobicContact CE1-CE2 4.04Å; Y112-F161 AromaticContact CE1-CZ 3.74Å; Y112-F161 HydrophobicContact CE1-CZ 3.74Å; Y112-F161 HydrophobicContact CG-CZ 4.3Å; V115-F161 HydrophobicContact CB-CE2 4.37Å; V115-F161 HydrophobicContact CB-CZ 4.33Å; V115-F161 HydrophobicContact CG1-CB 4.48Å; V115-F161 HydrophobicContact CG1-CD1 3.7Å; V115-F161 HydrophobicContact CG1-CD2 4.04Å; V115-F161 HydrophobicContact CG1-CE1 3.73Å; V115-F161 HydrophobicContact CG1-CE2 4.11Å; V115-F161 HydrophobicContact CG1-CG 3.82Å; V115-F161 HydrophobicContact CG1-CZ 3.94Å; V115-F161 HydrophobicContact CG2-CD2 4.39Å; V115-F161 HydrophobicContact CG2-CE2 4.35Å; F157-F161 WeakPolarHBondContact O-CB 3.2Å; F157-F161 PolarHBondContact O-N 2.74Å; F158-F161 AromaticContact CD2-CD1 3.71Å; F158-F161 HydrophobicContact CD2-CD1 3.71Å; F158-F161 HydrophobicContact CD2-CE1 4.4Å; F158-F161 AromaticContact CE2-CD1 3.7Å; F158-F161 HydrophobicContact CE2-CD1 3.7Å; F158-F161 AromaticContact CE2-CE1 3.98Å; F158-F161 HydrophobicContact CE2-CE1 3.98Å; F158-F161 WeakPolarHBondContact O-CB 3.21Å; F158-F161 PolarHBondContact O-N 3.1Å; I159-F161 VanDerWaalsContact C-N 3.3Å; I159-F161 PolarHBondContact O-N 2.82Å; F161-E163 VanDerWaalsContact C-N 3.34Å; F161-F167 HydrophobicContact CD1-CD2 4.37Å; F161-F167 HydrophobicContact CD1-CE2 4.06Å; F161-F167 HydrophobicContact CD2-CD2 4.45Å; F161-F167 HydrophobicContact CE1-CD2 4.09Å; F161-F167 AromaticContact CE1-CE2 3.51Å; F161-F167 HydrophobicContact CE1-CE2 3.51Å; F161-F167 HydrophobicContact CE2-CD2 4.15Å; F161-F167 HydrophobicContact CE2-CE2 4.27Å; F161-F167 AromaticContact CZ-CD2 3.98Å; F161-F167 HydrophobicContact CZ-CD2 3.98Å; F161-F167 AromaticContact CZ-CE2 3.63Å; F161-F167 HydrophobicContact CZ-CE2 3.63Å; F161-F167 WeakPolarHBondContact O-CD2 3.41Å
162	L	97.2	Very high	96.7	Very high	0 Å²	0	40.5 Å²	40.5	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-68.3	-32.6	178.9	-70.8	173.9	0	0	0	112.3	F158 I159 F167 I176 V202 R205 I206 K209	F158-L162 HydrophobicContact CD1-CD1 4.06Å; F158-L162 HydrophobicContact CD2-CG 4.37Å; F158-L162 HydrophobicContact CE1-CD1 3.82Å; F158-L162 HydrophobicContact CE2-CD1 4.33Å; F158-L162 HydrophobicContact CE2-CD2 4.3Å; F158-L162 HydrophobicContact CE2-CG 4.15Å; F158-L162 HydrophobicContact CG-CD1 4.44Å; F158-L162 HydrophobicContact CZ-CD1 3.96Å; F158-L162 HydrophobicContact CZ-CD2 4.28Å; F158-L162 HydrophobicContact CZ-CG 4.22Å; F158-L162 WeakPolarHBondContact O-CB 3.11Å; F158-L162 VanDerWaalsContact O-CG 3.31Å; F158-L162 WeakPolarHBondContact O-CG 3.38Å; F158-L162 PolarHBondContact O-N 3.24Å; I159-L162 CarbonylContact O-C 3.58Å; I159-L162 PolarHBondContact O-N 3.37Å; I159-L162 VanDerWaalsContact O-N 3.12Å; L162-F167 HydrophobicContact CD2-CE2 3.88Å; L162-F167 HydrophobicContact CD2-CZ 3.76Å; L162-I176 HydrophobicContact CD2-CD1 4.25Å; L162-V202 HydrophobicContact CD1-CG1 4.07Å; L162-R205 HydrophobicContact CB-CB 4.36Å; L162-R205 HydrophobicContact CD1-CB 4.26Å; L162-I206 HydrophobicContact CD1-CG1 4.07Å; L162-I206 HydrophobicContact CD2-CG1 4.49Å; L162-K209 WeakPolarHBondContact O-CD 3.3Å; L162-K209 WeakPolarHBondContact O-CE 3.34Å; L162-K209 PolarHBondContact O-NZ 3.14Å
163	E	96.1	Very high	96.6	Very high	76 Å²	76	43.4 Å²	43.4	36%	0.355	21%	0.212	S	C	.	.	H	α-helix	trans	-85.3	-15.4	-178.2	-70.9	-174.6	155.8	0	0	113.9	I159 R160 F161 Q165 R205	I159-E163 HydrophobicContact CG2-CG 4.13Å; I159-E163 WeakPolarHBondContact O-CB 3.36Å; I159-E163 WeakPolarHBondContact O-CG 3.48Å; I159-E163 PolarHBondContact O-N 3.02Å; R160-E163 PolarHBondContact O-N 3.4Å; F161-E163 VanDerWaalsContact C-N 3.34Å; E163-Q165 PolarHBondContact O-N 3.2Å; E163-R205 HydrophobicContact CG-CG 4.43Å; E163-R205 IonicContact OE1-CZ 3.08Å; E163-R205 IonicContact OE1-NE 2.65Å; E163-R205 PolarHBondContact OE1-NE 2.91Å; E163-R205 IonicContact OE1-NH2 2.64Å; E163-R205 PolarHBondContact OE1-NH2 3.26Å
164	S	95	Very high	96.5	Very high	24 Å²	24	49.2 Å²	49.2	17%	0.168	24%	0.237	C	C	.	.			trans	-51.3	136.9	176.8	178.3	0	0	0	0	111.9	R160 E166 F167	R160-S164 PolarHBondContact O-N 3.41Å; S164-E166 PolarHBondContact O-N 3.02Å; S164-E166 PolarHBondContact OG-N 3.19Å; S164-F167 WeakPolarHBondContact O-CB 3.26Å; S164-F167 PolarHBondContact O-N 2.73Å
165	Q	93.2	Very high	96.4	Very high	202 Å²	202	53.3 Å²	53.3	94%	0.944	25%	0.253	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.4	-22.3	175.4	-63.1	-176.7	7.1	0	0	112	E163 F167	E163-Q165 PolarHBondContact O-N 3.2Å; Q165-F167 VanDerWaalsContact C-N 3.3Å
166	E	93.6	Very high	96.3	Very high	69 Å²	69	53.4 Å²	53.4	32%	0.322	25%	0.253	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.8	-3.6	177.2	-59.7	-175.4	166.5	0	0	112.7	R104 G105 L107 S164 Q168	R104-E166 WeakPolarHBondContact CA-OE1 3.28Å; R104-E166 WeakPolarHBondContact CB-OE1 3.34Å; G105-E166 WeakPolarHBondContact CA-OE2 3.48Å; G105-E166 PolarHBondContact N-OE1 2.93Å; G105-E166 PolarHBondContact N-OE2 2.74Å; L107-E166 HydrophobicContact CD1-CB 4.31Å; S164-E166 PolarHBondContact O-N 3.02Å; S164-E166 PolarHBondContact OG-N 3.19Å; E166-Q168 PolarHBondContact O-N 3.02Å
167	F	95.7	Very high	96.3	Very high	14 Å²	14	54.6 Å²	54.6	6%	0.061	26%	0.261	C	S	.	.			trans	-66	125.9	-179.9	-178.1	-92.4	0	0	0	111.5	Y112 F161 L162 S164 Q165 P169 A172 K209 F210	Y112-F167 AromaticContact CE1-CD2 3.97Å; Y112-F167 HydrophobicContact CE1-CD2 3.97Å; Y112-F167 AromaticContact CE1-CE2 3.86Å; Y112-F167 HydrophobicContact CE1-CE2 3.86Å; F161-F167 HydrophobicContact CD1-CD2 4.37Å; F161-F167 HydrophobicContact CD1-CE2 4.06Å; F161-F167 HydrophobicContact CD2-CD2 4.45Å; F161-F167 HydrophobicContact CE1-CD2 4.09Å; F161-F167 AromaticContact CE1-CE2 3.51Å; F161-F167 HydrophobicContact CE1-CE2 3.51Å; F161-F167 HydrophobicContact CE2-CD2 4.15Å; F161-F167 HydrophobicContact CE2-CE2 4.27Å; F161-F167 AromaticContact CZ-CD2 3.98Å; F161-F167 HydrophobicContact CZ-CD2 3.98Å; F161-F167 AromaticContact CZ-CE2 3.63Å; F161-F167 HydrophobicContact CZ-CE2 3.63Å; F161-F167 WeakPolarHBondContact O-CD2 3.41Å; L162-F167 HydrophobicContact CD2-CE2 3.88Å; L162-F167 HydrophobicContact CD2-CZ 3.76Å; S164-F167 WeakPolarHBondContact O-CB 3.26Å; S164-F167 PolarHBondContact O-N 2.73Å; Q165-F167 VanDerWaalsContact C-N 3.3Å; F167-P169 HydrophobicContact CD1-CG 4.1Å; F167-P169 HydrophobicContact CE1-CB 4.35Å; F167-P169 HydrophobicContact CE1-CG 3.96Å; F167-P169 WeakPolarHBondContact O-CD 3.44Å; F167-A172 HydrophobicContact CE1-CB 4.27Å; F167-A172 HydrophobicContact CE2-CB 3.91Å; F167-A172 HydrophobicContact CZ-CB 3.49Å; F167-A172 VanDerWaalsContact CZ-CB 3.49Å; F167-K209 HydrophobicContact CD1-CD 3.67Å; F167-K209 HydrophobicContact CE1-CB 4.48Å; F167-K209 HydrophobicContact CE1-CD 3.79Å; F167-F210 HydrophobicContact CE1-CE2 4.3Å; F167-F210 HydrophobicContact CE1-CZ 4.02Å; F167-F210 HydrophobicContact CZ-CE2 4.09Å; F167-F210 AromaticContact CZ-CZ 3.71Å; F167-F210 HydrophobicContact CZ-CZ 3.71Å
168	Q	96.1	Very high	96.2	Very high	94 Å²	94	59.6 Å²	59.6	44%	0.439	29%	0.285	S	S	.	.			trans	-111.8	104	-178.4	-65.2	-174.8	42.2	0	0	111.1	Y112 E166 S170 I171 A172	Y112-Q168 PolarHBondContact OH-N 2.87Å; E166-Q168 PolarHBondContact O-N 3.02Å; Q168-S170 PolarHBondContact O-N 2.88Å; Q168-S170 VanDerWaalsContact O-N 3.14Å; Q168-I171 HydrophobicContact CB-CD1 3.94Å; Q168-I171 HydrophobicContact CB-CG1 4.34Å; Q168-I171 HydrophobicContact CG-CD1 4.42Å; Q168-I171 PolarHBondContact O-N 2.78Å; Q168-I171 VanDerWaalsContact O-N 3.16Å; Q168-A172 PolarHBondContact O-N 3.17Å
169	P	95.8	Very high	96.2	Very high	48 Å²	48	66.1 Å²	66.1	31%	0.312	31%	0.313	S	S	.	.	H	α-helix	trans	-59.4	-27.8	179.3	-24.2	33.4	0	0	0	113.8	F167 I171 K173 K209 F210	F167-P169 HydrophobicContact CD1-CG 4.1Å; F167-P169 HydrophobicContact CE1-CB 4.35Å; F167-P169 HydrophobicContact CE1-CG 3.96Å; F167-P169 WeakPolarHBondContact O-CD 3.44Å; P169-I171 VanDerWaalsContact C-N 3.31Å; P169-I171 PolarHBondContact O-N 3.47Å; P169-K173 WeakPolarHBondContact O-CB 3.38Å; P169-K173 PolarHBondContact O-N 3.26Å; P169-K209 HydrophobicContact CG-CB 4.36Å; P169-F210 HydrophobicContact CB-CD1 4.35Å; P169-F210 HydrophobicContact CB-CE1 4.13Å
170	S	95.3	Very high	96.2	Very high	68 Å²	68	65.6 Å²	65.6	48%	0.476	31%	0.31	S	S	.	.	H	α-helix	trans	-63.8	-31.8	178.6	52.3	0	0	0	0	113.7	Q168 K173	Q168-S170 PolarHBondContact O-N 2.88Å; Q168-S170 VanDerWaalsContact O-N 3.14Å; S170-K173 VanDerWaalsContact O-CE 3.24Å; S170-K173 WeakPolarHBondContact O-CE 3.09Å; S170-K173 WeakPolarHBondContact O-CG 3.35Å
171	I	96.1	Very high	96.2	Very high	13 Å²	13	61.5 Å²	61.5	7%	0.067	30%	0.295	C	S	.	.	H	α-helix	trans	-85.8	-50.1	175.5	-61.6	164	0	0	0	109	E109 Y112 Q168 P169 K173 K174	E109-I171 HydrophobicContact CG-CD1 3.85Å; E109-I171 HydrophobicContact CG-CG1 4.49Å; Y112-I171 HydrophobicContact CD1-CG2 4.24Å; Y112-I171 HydrophobicContact CD2-CB 4.4Å; Y112-I171 HydrophobicContact CD2-CG2 3.67Å; Y112-I171 HydrophobicContact CE2-CB 4.41Å; Y112-I171 HydrophobicContact CE2-CD1 4.32Å; Y112-I171 HydrophobicContact CE2-CG2 4.13Å; Y112-I171 HydrophobicContact CG-CG2 3.76Å; Q168-I171 HydrophobicContact CB-CD1 3.94Å; Q168-I171 HydrophobicContact CB-CG1 4.34Å; Q168-I171 HydrophobicContact CG-CD1 4.42Å; Q168-I171 PolarHBondContact O-N 2.78Å; Q168-I171 VanDerWaalsContact O-N 3.16Å; P169-I171 VanDerWaalsContact C-N 3.31Å; P169-I171 PolarHBondContact O-N 3.47Å; I171-K173 VanDerWaalsContact C-N 3.25Å; I171-K173 PolarHBondContact O-N 3.33Å; I171-K174 WeakPolarHBondContact O-CB 3.33Å; I171-K174 PolarHBondContact O-N 2.91Å
172	A	96.6	Very high	96.2	Very high	0 Å²	0	64.7 Å²	64.7	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-59.5	-31.5	-175.2	0	0	0	0	0	113.9	Y112 F167 Q168 K174 Y175 I176 F210	Y112-A172 HydrophobicContact CD1-CB 3.67Å; Y112-A172 HydrophobicContact CE1-CB 3.78Å; F167-A172 HydrophobicContact CE1-CB 4.27Å; F167-A172 HydrophobicContact CE2-CB 3.91Å; F167-A172 HydrophobicContact CZ-CB 3.49Å; F167-A172 VanDerWaalsContact CZ-CB 3.49Å; Q168-A172 PolarHBondContact O-N 3.17Å; A172-K174 PolarHBondContact O-N 2.83Å; A172-Y175 PolarHBondContact O-N 3.39Å; A172-I176 HydrophobicContact CB-CD1 4.46Å; A172-I176 PolarHBondContact O-N 3.22Å; A172-F210 HydrophobicContact CB-CE1 3.91Å; A172-F210 HydrophobicContact CB-CZ 3.63Å
173	K	95.4	Very high	96.3	Very high	135 Å²	135	67.9 Å²	67.9	59%	0.587	33%	0.326	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.8	-17.3	179.8	70.9	-179.5	-176	176.1	0	114.2	P169 S170 I171 F210	P169-K173 WeakPolarHBondContact O-CB 3.38Å; P169-K173 PolarHBondContact O-N 3.26Å; S170-K173 VanDerWaalsContact O-CE 3.24Å; S170-K173 WeakPolarHBondContact O-CE 3.09Å; S170-K173 WeakPolarHBondContact O-CG 3.35Å; I171-K173 VanDerWaalsContact C-N 3.25Å; I171-K173 PolarHBondContact O-N 3.33Å; K173-F210 HydrophobicContact CB-CD1 4.2Å; K173-F210 HydrophobicContact CB-CE1 4.07Å
174	K	95.5	Very high	96.4	Very high	138 Å²	138	64.3 Å²	64.3	60%	0.6	31%	0.31	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.6	-20.5	174.9	-63.2	177.2	-177.1	173.5	0	112.4	I171 A172	I171-K174 WeakPolarHBondContact O-CB 3.33Å; I171-K174 PolarHBondContact O-N 2.91Å; A172-K174 PolarHBondContact O-N 2.83Å
175	Y	96.7	Very high	96.5	Very high	87 Å²	87	63.2 Å²	63.2	34%	0.341	30%	0.302	S	S	.	.	T	Hydrogen-bonded Turn	trans	-121.3	-31.1	-172.2	-51	-70.4	0	0	0	112.5	P113 A172 D177	P113-Y175 HydrophobicContact CB-CD1 4.06Å; P113-Y175 HydrophobicContact CB-CE1 3.64Å; P113-Y175 HydrophobicContact CB-CE2 4.38Å; P113-Y175 HydrophobicContact CG-CE1 4.3Å; P113-Y175 HydrophobicContact CG-CE2 4.44Å; A172-Y175 PolarHBondContact O-N 3.39Å; Y175-D177 PolarHBondContact O-N 3.19Å
176	I	97.4	Very high	96.7	Very high	2 Å²	2	59.2 Å²	59.2	1%	0.01	28%	0.283	C	S	.	.	S	Bend	trans	-95.3	84.6	171.4	-58	177.3	0	0	0	107.3	V116 F158 L162 A172 F180 I206 F210 L213	V116-I176 HydrophobicContact CG2-CD1 4.46Å; V116-I176 HydrophobicContact CG2-CG1 4Å; F158-I176 HydrophobicContact CE2-CD1 4.43Å; F158-I176 HydrophobicContact CZ-CD1 4.13Å; L162-I176 HydrophobicContact CD2-CD1 4.25Å; A172-I176 HydrophobicContact CB-CD1 4.46Å; A172-I176 PolarHBondContact O-N 3.22Å; I176-F180 HydrophobicContact CG2-CD1 3.86Å; I176-F180 HydrophobicContact CG2-CE1 4.33Å; I176-F180 HydrophobicContact CG2-CG 4.38Å; I176-I206 HydrophobicContact CG2-CD1 4.37Å; I176-I206 HydrophobicContact CG2-CG2 4.33Å; I176-F210 HydrophobicContact CB-CE2 4.5Å; I176-F210 HydrophobicContact CB-CZ 4.19Å; I176-F210 HydrophobicContact CD1-CE2 4.03Å; I176-F210 HydrophobicContact CD1-CZ 3.88Å; I176-F210 HydrophobicContact CG2-CE2 4.22Å; I176-F210 HydrophobicContact CG2-CZ 4.39Å; I176-L213 HydrophobicContact CG2-CD1 4.19Å
177	D	96.4	Very high	96.9	Very high	74 Å²	74	56 Å²	56	40%	0.396	27%	0.268	S	S	.	.			trans	-104.1	-171.5	-178.8	71.1	-0.6	0	0	0	111.9	Y175 K179 F180 V181	Y175-D177 PolarHBondContact O-N 3.19Å; D177-K179 VanDerWaalsContact C-N 3.26Å; D177-K179 PolarHBondContact O-N 3.44Å; D177-K179 WeakPolarHBondContact OD1-CA 3.41Å; D177-K179 WeakPolarHBondContact OD1-CB 3.3Å; D177-K179 PolarHBondContact OD1-N 3.01Å; D177-F180 PolarHBondContact O-N 2.84Å; D177-F180 PolarHBondContact OD1-N 2.94Å; D177-V181 WeakPolarHBondContact O-CG2 3.46Å; D177-V181 PolarHBondContact O-N 3.25Å; D177-V181 VanDerWaalsContact O-N 3.14Å
178	Q	97.9	Very high	97	Very high	105 Å²	105	55.3 Å²	55.3	49%	0.491	27%	0.265	S	S	.	.	H	α-helix	trans	-63.8	-31.6	177.8	-69.2	-177.4	3.5	0	0	112.8	V181 L182 L213 F216	Q178-V181 PolarHBondContact O-N 3.45Å; Q178-L182 WeakPolarHBondContact O-CB 3.47Å; Q178-L182 PolarHBondContact O-N 2.99Å; Q178-L213 HydrophobicContact CG-CD2 4.1Å; Q178-F216 HydrophobicContact CB-CD1 4.1Å; Q178-F216 HydrophobicContact CB-CD2 4.24Å; Q178-F216 HydrophobicContact CB-CE1 3.78Å; Q178-F216 HydrophobicContact CB-CE2 3.93Å; Q178-F216 HydrophobicContact CB-CG 4.32Å; Q178-F216 HydrophobicContact CB-CZ 3.69Å; Q178-F216 VanDerWaalsContact CD-CD2 3.49Å; Q178-F216 HydrophobicContact CG-CB 4.37Å; Q178-F216 HydrophobicContact CG-CD1 3.93Å; Q178-F216 HydrophobicContact CG-CD2 3.83Å; Q178-F216 HydrophobicContact CG-CE1 4.14Å; Q178-F216 HydrophobicContact CG-CE2 4.03Å; Q178-F216 HydrophobicContact CG-CG 3.77Å; Q178-F216 HydrophobicContact CG-CZ 4.19Å; Q178-F216 VanDerWaalsContact O-CE1 3.31Å; Q178-F216 WeakPolarHBondContact O-CE1 3.37Å
179	K	97.3	Very high	97	Very high	136 Å²	136	52.9 Å²	52.9	59%	0.591	26%	0.255	S	S	*	.	H	α-helix	trans	-68.9	-45.5	178.2	-179.1	-176.1	175.3	-176.4	0	110.3	D177 V181 L182 Q183	D177-K179 VanDerWaalsContact C-N 3.26Å; D177-K179 PolarHBondContact O-N 3.44Å; D177-K179 WeakPolarHBondContact OD1-CA 3.41Å; D177-K179 WeakPolarHBondContact OD1-CB 3.3Å; D177-K179 PolarHBondContact OD1-N 3.01Å; K179-V181 VanDerWaalsContact C-N 3.3Å; K179-V181 PolarHBondContact O-N 3.32Å; K179-L182 PolarHBondContact O-N 3.45Å; K179-Q183 WeakPolarHBondContact O-CG 3.43Å; K179-Q183 PolarHBondContact O-N 2.86Å
180	F	98.1	Very high	96.9	Very high	6 Å²	6	51 Å²	51	3%	0.026	24%	0.243	C	C	.	.	H	α-helix	trans	-55.3	-47.2	174	-175.6	-81.4	0	0	0	111.1	V116 F124 F158 I176 D177 L182 Q183 L184 I206	V116-F180 HydrophobicContact CG1-CD2 3.95Å; V116-F180 HydrophobicContact CG1-CE2 3.89Å; F124-F180 AromaticContact CE2-CD2 3.56Å; F124-F180 HydrophobicContact CE2-CD2 3.56Å; F124-F180 AromaticContact CE2-CE2 3.59Å; F124-F180 HydrophobicContact CE2-CE2 3.59Å; F124-F180 HydrophobicContact CE2-CG 4.24Å; F124-F180 HydrophobicContact CE2-CZ 4.31Å; F124-F180 HydrophobicContact CZ-CD1 4.18Å; F124-F180 AromaticContact CZ-CD2 3.6Å; F124-F180 HydrophobicContact CZ-CD2 3.6Å; F124-F180 HydrophobicContact CZ-CE1 4.08Å; F124-F180 AromaticContact CZ-CE2 3.48Å; F124-F180 HydrophobicContact CZ-CE2 3.48Å; F124-F180 VanDerWaalsContact CZ-CE2 3.48Å; F124-F180 AromaticContact CZ-CG 3.95Å; F124-F180 HydrophobicContact CZ-CG 3.95Å; F124-F180 AromaticContact CZ-CZ 3.73Å; F124-F180 HydrophobicContact CZ-CZ 3.73Å; F158-F180 HydrophobicContact CE1-CE1 4.17Å; F158-F180 AromaticContact CE1-CZ 3.86Å; F158-F180 HydrophobicContact CE1-CZ 3.86Å; F158-F180 HydrophobicContact CZ-CE1 4.1Å; F158-F180 AromaticContact CZ-CZ 3.7Å; F158-F180 HydrophobicContact CZ-CZ 3.7Å; I176-F180 HydrophobicContact CG2-CD1 3.86Å; I176-F180 HydrophobicContact CG2-CE1 4.33Å; I176-F180 HydrophobicContact CG2-CG 4.38Å; D177-F180 PolarHBondContact O-N 2.84Å; D177-F180 PolarHBondContact OD1-N 2.94Å; F180-L182 PolarHBondContact O-N 3.38Å; F180-Q183 PolarHBondContact O-N 3.3Å; F180-L184 HydrophobicContact CE1-CD2 4.43Å; F180-L184 WeakPolarHBondContact O-CB 3.49Å; F180-L184 PolarHBondContact O-N 2.96Å; F180-I206 HydrophobicContact CE1-CD1 4.01Å
181	V	98.3	Very high	96.7	Very high	0 Å²	0	49.2 Å²	49.2	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-62.7	-40.7	178.1	170.2	0	0	0	0	112.1	D177 Q178 K179 L184 L185 I206 L213 F216 I217	D177-V181 WeakPolarHBondContact O-CG2 3.46Å; D177-V181 PolarHBondContact O-N 3.25Å; D177-V181 VanDerWaalsContact O-N 3.14Å; Q178-V181 PolarHBondContact O-N 3.45Å; K179-V181 VanDerWaalsContact C-N 3.3Å; K179-V181 PolarHBondContact O-N 3.32Å; V181-L184 PolarHBondContact O-N 3.44Å; V181-L185 HydrophobicContact CG1-CD1 3.94Å; V181-L185 HydrophobicContact CG1-CG 4.4Å; V181-L185 WeakPolarHBondContact O-CB 3.31Å; V181-L185 WeakPolarHBondContact O-CG 3.37Å; V181-L185 PolarHBondContact O-N 2.99Å; V181-I206 HydrophobicContact CG2-CG2 4.32Å; V181-L213 HydrophobicContact CG2-CD1 3.95Å; V181-F216 HydrophobicContact CB-CD1 4.37Å; V181-F216 HydrophobicContact CB-CE1 4.17Å; V181-F216 HydrophobicContact CG1-CD1 4Å; V181-F216 HydrophobicContact CG1-CE1 3.97Å; V181-I217 HydrophobicContact CG1-CD1 4.48Å; V181-I217 HydrophobicContact CG1-CG1 3.63Å
182	L	97.7	Very high	96.6	Very high	68 Å²	68	48.7 Å²	48.7	36%	0.356	22%	0.224	S	C	.	.	H	α-helix	trans	-63	-48	178.9	-175.6	65.4	0	0	0	111.2	Q178 K179 F180 L184 L185 E186	Q178-L182 WeakPolarHBondContact O-CB 3.47Å; Q178-L182 PolarHBondContact O-N 2.99Å; K179-L182 PolarHBondContact O-N 3.45Å; F180-L182 PolarHBondContact O-N 3.38Å; L182-L184 VanDerWaalsContact C-N 3.28Å; L182-L184 PolarHBondContact O-N 3.34Å; L182-L185 PolarHBondContact O-N 2.91Å; L182-L185 VanDerWaalsContact O-N 3.16Å; L182-E186 WeakPolarHBondContact O-CG 3.42Å; L182-E186 PolarHBondContact O-N 3.01Å
183	Q	97.6	Very high	96.4	Very high	67 Å²	67	51.2 Å²	51.2	31%	0.313	24%	0.241	S	C	.	.	H	α-helix	trans	-63.9	-35.1	177.2	-64	-174.4	-86	0	0	111.9	F124 K179 F180 E186	F124-Q183 HydrophobicContact CD1-CB 3.61Å; F124-Q183 HydrophobicContact CD2-CB 4.13Å; F124-Q183 HydrophobicContact CE1-CB 3.76Å; F124-Q183 HydrophobicContact CE2-CB 4.22Å; F124-Q183 HydrophobicContact CG-CB 3.85Å; F124-Q183 HydrophobicContact CZ-CB 4.06Å; K179-Q183 WeakPolarHBondContact O-CG 3.43Å; K179-Q183 PolarHBondContact O-N 2.86Å; F180-Q183 PolarHBondContact O-N 3.3Å; Q183-E186 PolarHBondContact O-N 3.49Å
184	L	98.3	Very high	96.5	Very high	0 Å²	0	49 Å²	49	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-65.5	-40.4	174	-172.2	73.3	0	0	0	112	I123 F124 F180 V181 L182 E186 L187 L199 V202 L203 I206	I123-L184 HydrophobicContact CD1-CD1 3.94Å; F124-L184 HydrophobicContact CE1-CB 4.01Å; F124-L184 HydrophobicContact CE1-CD1 4.27Å; F124-L184 HydrophobicContact CZ-CB 4.47Å; F180-L184 HydrophobicContact CE1-CD2 4.43Å; F180-L184 WeakPolarHBondContact O-CB 3.49Å; F180-L184 PolarHBondContact O-N 2.96Å; V181-L184 PolarHBondContact O-N 3.44Å; L182-L184 VanDerWaalsContact C-N 3.28Å; L182-L184 PolarHBondContact O-N 3.34Å; L184-E186 VanDerWaalsContact C-N 3.35Å; L184-L187 PolarHBondContact O-N 3.17Å; L184-L199 HydrophobicContact CD1-CD2 3.46Å; L184-L199 VanDerWaalsContact CD1-CD2 3.46Å; L184-L199 HydrophobicContact CG-CD2 4.14Å; L184-V202 HydrophobicContact CD1-CG1 4.26Å; L184-V202 HydrophobicContact CD2-CG1 3.9Å; L184-L203 HydrophobicContact CD2-CB 4.35Å; L184-L203 HydrophobicContact CD2-CD1 4.26Å; L184-I206 HydrophobicContact CD2-CD1 3.75Å
185	L	98.3	Very high	96.6	Very high	2 Å²	2	42.4 Å²	42.4	1%	0.01	20%	0.2	C	C	.	.	H	α-helix	trans	-67.7	-33.7	177.9	-78.5	169.8	0	0	0	112.5	V181 L182 L187 F188 L203 Q220 I221 I224 L241	V181-L185 HydrophobicContact CG1-CD1 3.94Å; V181-L185 HydrophobicContact CG1-CG 4.4Å; V181-L185 WeakPolarHBondContact O-CB 3.31Å; V181-L185 WeakPolarHBondContact O-CG 3.37Å; V181-L185 PolarHBondContact O-N 2.99Å; L182-L185 PolarHBondContact O-N 2.91Å; L182-L185 VanDerWaalsContact O-N 3.16Å; L185-L187 PolarHBondContact O-N 3.32Å; L185-F188 HydrophobicContact CD2-CD2 4.39Å; L185-F188 HydrophobicContact CD2-CE2 4.42Å; L185-F188 WeakPolarHBondContact O-CB 2.87Å; L185-F188 PolarHBondContact O-N 3.1Å; L185-L203 HydrophobicContact CD2-CD1 4.45Å; L185-L203 HydrophobicContact CD2-CD2 3.54Å; L185-Q220 HydrophobicContact CD1-CB 3.47Å; L185-Q220 VanDerWaalsContact CD1-CB 3.47Å; L185-Q220 HydrophobicContact CD1-CG 4.24Å; L185-I221 HydrophobicContact CD2-CG1 4.08Å; L185-I224 HydrophobicContact CB-CD1 4.17Å; L185-I224 HydrophobicContact CD2-CD1 4.34Å; L185-L241 HydrophobicContact CD2-CD2 4.13Å
186	E	96.9	Very high	96.7	Very high	118 Å²	118	39.9 Å²	39.9	55%	0.551	19%	0.19	S	C	*	.	H	α-helix	trans	-61.3	-31.4	174.7	-72.6	171.6	-175.3	0	0	112.3	L182 Q183 L184 F188 D189	L182-E186 WeakPolarHBondContact O-CG 3.42Å; L182-E186 PolarHBondContact O-N 3.01Å; Q183-E186 PolarHBondContact O-N 3.49Å; L184-E186 VanDerWaalsContact C-N 3.35Å; E186-F188 VanDerWaalsContact C-N 3.26Å; E186-F188 PolarHBondContact O-N 3.25Å; E186-D189 PolarHBondContact O-N 3.09Å
187	L	97.7	Very high	96.7	Very high	1 Å²	1	43.4 Å²	43.4	1%	0.005	21%	0.209	C	C	.	.	G	3₁₀ helix	trans	-71.4	-16.1	179	-61.2	177	0	0	0	113.9	I123 F124 L127 L184 L185 D189 S190 L199	I123-L187 HydrophobicContact CB-CD1 4Å; I123-L187 HydrophobicContact CD1-CD1 4.19Å; I123-L187 HydrophobicContact CG1-CD1 3.99Å; I123-L187 WeakPolarHBondContact O-CD1 3.5Å; I123-L187 WeakPolarHBondContact O-CD2 3.28Å; F124-L187 HydrophobicContact CD1-CD1 3.87Å; F124-L187 HydrophobicContact CE1-CD1 4.27Å; L127-L187 HydrophobicContact CD2-CD2 4.29Å; L184-L187 PolarHBondContact O-N 3.17Å; L185-L187 PolarHBondContact O-N 3.32Å; L187-D189 PolarHBondContact O-N 3.38Å; L187-D189 VanDerWaalsContact O-N 3.13Å; L187-S190 VanDerWaalsContact O-CB 3.26Å; L187-S190 WeakPolarHBondContact O-CB 3.29Å; L187-S190 PolarHBondContact O-N 3.28Å; L187-L199 VanDerWaalsContact C-CD1 3.41Å; L187-L199 HydrophobicContact CB-CD1 3.56Å; L187-L199 HydrophobicContact CB-CD2 3.93Å; L187-L199 HydrophobicContact CB-CG 4.41Å; L187-L199 HydrophobicContact CD1-CD2 4.09Å; L187-L199 VanDerWaalsContact O-CD1 3.23Å; L187-L199 WeakPolarHBondContact O-CD1 3.26Å
188	F	97.8	Very high	96.8	Very high	0 Å²	0	42.1 Å²	42.1	0%	0	20%	0.199	C	C	.	.	G	3₁₀ helix	trans	-64.2	-15.1	175.9	-86.6	-99.1	0	0	0	112.6	L185 E186 S190 R196 L199 K200 L203 F235 G237 E240 L241 I244	L185-F188 HydrophobicContact CD2-CD2 4.39Å; L185-F188 HydrophobicContact CD2-CE2 4.42Å; L185-F188 WeakPolarHBondContact O-CB 2.87Å; L185-F188 PolarHBondContact O-N 3.1Å; E186-F188 VanDerWaalsContact C-N 3.26Å; E186-F188 PolarHBondContact O-N 3.25Å; F188-S190 PolarHBondContact O-N 3.42Å; F188-R196 WeakPolarHBondContact O-CD 3.35Å; F188-L199 HydrophobicContact CD2-CB 4.11Å; F188-L199 HydrophobicContact CD2-CD1 4.33Å; F188-L199 HydrophobicContact CE1-CB 4.15Å; F188-L199 HydrophobicContact CE2-CB 3.71Å; F188-L199 VanDerWaalsContact CZ-C 3.45Å; F188-L199 HydrophobicContact CZ-CB 3.74Å; F188-L199 WeakPolarHBondContact CZ-O 3.35Å; F188-K200 HydrophobicContact CE1-CB 4.45Å; F188-L203 HydrophobicContact CE2-CB 4.1Å; F188-L203 HydrophobicContact CE2-CD2 3.65Å; F188-L203 HydrophobicContact CE2-CG 4.48Å; F188-L203 HydrophobicContact CZ-CB 3.96Å; F188-L203 HydrophobicContact CZ-CD2 3.67Å; F188-L203 HydrophobicContact CZ-CG 4.47Å; F188-F235 HydrophobicContact CB-CE1 4.11Å; F188-F235 HydrophobicContact CB-CZ 3.63Å; F188-G237 VanDerWaalsContact O-CA 3.22Å; F188-G237 WeakPolarHBondContact O-CA 3.04Å; F188-G237 PolarHBondContact O-N 3.41Å; F188-G237 VanDerWaalsContact O-N 3.13Å; F188-E240 HydrophobicContact CD1-CB 4.23Å; F188-E240 HydrophobicContact CE1-CB 4.02Å; F188-L241 HydrophobicContact CD1-CD2 3.7Å; F188-L241 HydrophobicContact CD1-CG 3.9Å; F188-L241 HydrophobicContact CD2-CD2 4.28Å; F188-L241 HydrophobicContact CE1-CD2 3.66Å; F188-L241 HydrophobicContact CE1-CG 4.22Å; F188-L241 HydrophobicContact CE2-CD2 4.23Å; F188-L241 HydrophobicContact CG-CD2 4.01Å; F188-L241 HydrophobicContact CG-CG 4.35Å; F188-L241 HydrophobicContact CZ-CD2 3.93Å; F188-I244 HydrophobicContact CE1-CD1 4.18Å; F188-I244 HydrophobicContact CZ-CD1 3.95Å
189	D	95.4	Very high	96.8	Very high	42 Å²	42	37.1 Å²	37.1	23%	0.225	18%	0.176	C	C	.	.	G	3₁₀ helix	trans	-80.4	4.5	173.3	-147.4	17.5	0	0	0	113.2	L127 E186 L187 E191 F235 N236	L127-D189 VanDerWaalsContact CD1-C 3.43Å; L127-D189 HydrophobicContact CD1-CB 3.74Å; E186-D189 PolarHBondContact O-N 3.09Å; L187-D189 PolarHBondContact O-N 3.38Å; L187-D189 VanDerWaalsContact O-N 3.13Å; D189-E191 PolarHBondContact O-N 3.42Å; D189-F235 HydrophobicContact CB-CD2 3.96Å; D189-F235 HydrophobicContact CB-CE2 3.73Å; D189-F235 VanDerWaalsContact OD1-CA 3.26Å; D189-F235 WeakPolarHBondContact OD1-CA 3.21Å; D189-F235 WeakPolarHBondContact OD1-CD2 3.22Å; D189-N236 PolarHBondContact O-ND2 3.34Å; D189-N236 PolarHBondContact OD1-N 3.45Å
190	S	93.7	Very high	96.9	Very high	8 Å²	8	32.2 Å²	32.2	6%	0.056	16%	0.155	C	C	.	.			trans	-58.4	133.4	175.3	-176.4	0	0	0	0	110.9	L187 F188 D192 E195 R196	L187-S190 VanDerWaalsContact O-CB 3.26Å; L187-S190 WeakPolarHBondContact O-CB 3.29Å; L187-S190 PolarHBondContact O-N 3.28Å; F188-S190 PolarHBondContact O-N 3.42Å; S190-D192 PolarHBondContact O-N 3.39Å; S190-D192 PolarHBondContact OG-N 3.43Å; S190-E195 WeakPolarHBondContact CB-OE2 3.36Å; S190-E195 PolarHBondContact OG-OE2 3.41Å; S190-R196 VanDerWaalsContact O-CD 3.29Å; S190-R196 WeakPolarHBondContact O-CD 3.47Å; S190-R196 PolarHBondContact O-NH1 3.41Å
191	E	91.6	Very high	96.9	Very high	32 Å²	32	33.9 Å²	33.9	15%	0.15	17%	0.165	C	C	.	.	S	Bend	trans	-66.7	-25.3	174	-73.1	-171.7	-156.4	0	0	112	T143 D189 P193 R196	T143-E191 WeakPolarHBondContact CB-OE2 3.18Å; T143-E191 PolarHBondContact N-OE2 3.08Å; T143-E191 VanDerWaalsContact N-OE2 3.1Å; T143-E191 PolarHBondContact OG1-OE2 3.36Å; D189-E191 PolarHBondContact O-N 3.42Å; E191-P193 WeakPolarHBondContact O-CD 3.26Å; E191-R196 VanDerWaalsContact C-NH1 3.28Å; E191-R196 PolarHBondContact O-NH1 2.93Å
192	D	93.3	Very high	96.9	Very high	1 Å²	1	33.9 Å²	33.9	1%	0.005	17%	0.165	C	C	.	.			trans	-76.1	109.6	-178.3	-165	-36	0	0	0	111	E145 S190 R194 E195 R196	E145-D192 HydrophobicContact CB-CB 4.4Å; E145-D192 PolarHBondContact N-OD2 3.28Å; S190-D192 PolarHBondContact O-N 3.39Å; S190-D192 PolarHBondContact OG-N 3.43Å; D192-R194 PolarHBondContact O-N 3.45Å; D192-R194 VanDerWaalsContact O-N 3.14Å; D192-R194 WeakPolarHBondContact OD1-CB 3.23Å; D192-R194 WeakPolarHBondContact OD1-CG 3.3Å; D192-R194 IonicContact OD1-CZ 2.69Å; D192-R194 PolarHBondContact OD1-N 2.67Å; D192-R194 IonicContact OD1-NE 3.92Å; D192-R194 PolarHBondContact OD1-NE 2.77Å; D192-R194 IonicContact OD1-NH2 3.29Å; D192-R194 IonicContact OD2-CZ 3.05Å; D192-R194 IonicContact OD2-NE 3.2Å; D192-R194 PolarHBondContact OD2-NE 2.99Å; D192-R194 IonicContact OD2-NH2 3.63Å; D192-R194 PolarHBondContact OD2-NH2 3.13Å; D192-E195 HydrophobicContact CB-CB 4.26Å; D192-E195 PolarHBondContact O-N 3.34Å; D192-E195 VanDerWaalsContact O-N 3.1Å; D192-R196 PolarHBondContact O-N 3.35Å
193	P	94.2	Very high	96.9	Very high	54 Å²	54	30.6 Å²	30.6	35%	0.351	15%	0.148	S	C	.	.	H	α-helix	trans	-62	-25.5	-178.2	25.7	-34.4	0	0	0	112.7	E191 R196 D197	E191-P193 WeakPolarHBondContact O-CD 3.26Å; P193-R196 PolarHBondContact O-N 2.95Å; P193-D197 PolarHBondContact O-N 3.42Å
194	R	96.9	Very high	97	Very high	88 Å²	88	30.1 Å²	30.1	33%	0.332	15%	0.146	S	C	.	.	H	α-helix	trans	-66.8	-43.2	178.2	-52.1	171.1	-67.6	179.8	4.9	109.9	W148 D192 D197 Y198	W148-R194 VanDerWaalsContact CD1-NH1 3.26Å; W148-R194 VanDerWaalsContact CH2-C 3.48Å; W148-R194 HydrophobicContact CH2-CB 3.57Å; W148-R194 HydrophobicContact CZ2-CB 3.36Å; W148-R194 HydrophobicContact CZ2-CG 4.4Å; W148-R194 HydrophobicContact CZ3-CB 4.26Å; D192-R194 PolarHBondContact O-N 3.45Å; D192-R194 VanDerWaalsContact O-N 3.14Å; D192-R194 WeakPolarHBondContact OD1-CB 3.23Å; D192-R194 WeakPolarHBondContact OD1-CG 3.3Å; D192-R194 IonicContact OD1-CZ 2.69Å; D192-R194 PolarHBondContact OD1-N 2.67Å; D192-R194 IonicContact OD1-NE 3.92Å; D192-R194 PolarHBondContact OD1-NE 2.77Å; D192-R194 IonicContact OD1-NH2 3.29Å; D192-R194 IonicContact OD2-CZ 3.05Å; D192-R194 IonicContact OD2-NE 3.2Å; D192-R194 PolarHBondContact OD2-NE 2.99Å; D192-R194 IonicContact OD2-NH2 3.63Å; D192-R194 PolarHBondContact OD2-NH2 3.13Å; R194-D197 PolarHBondContact O-N 3.25Å; R194-Y198 WeakPolarHBondContact O-CD2 3.47Å; R194-Y198 PolarHBondContact O-N 2.85Å
195	E	97.6	Very high	97	Very high	0 Å²	0	34.4 Å²	34.4	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-62.5	-44.6	177	-171.7	169.1	-162.4	0	0	110.9	R125 W148 Y155 S190 D192 D197 Y198 L199	R125-E195 IonicContact CZ-OE1 2.75Å; R125-E195 IonicContact CZ-OE2 2.77Å; R125-E195 IonicContact NH1-OE1 3.15Å; R125-E195 PolarHBondContact NH1-OE1 3.34Å; R125-E195 IonicContact NH1-OE2 2.68Å; R125-E195 VanDerWaalsContact NH2-CD 3.35Å; R125-E195 IonicContact NH2-OE1 2.66Å; R125-E195 PolarHBondContact NH2-OE1 3.1Å; R125-E195 VanDerWaalsContact NH2-OE1 3.09Å; R125-E195 IonicContact NH2-OE2 3.81Å; R125-E195 PolarHBondContact NH2-OE2 2.82Å; W148-E195 HydrophobicContact CH2-CB 4.42Å; W148-E195 HydrophobicContact CZ3-CB 3.79Å; W148-E195 HydrophobicContact CZ3-CG 4.4Å; Y155-E195 HydrophobicContact CE2-CG 3.81Å; Y155-E195 WeakPolarHBondContact OH-CG 3.35Å; Y155-E195 PolarHBondContact OH-OE1 3.39Å; S190-E195 WeakPolarHBondContact CB-OE2 3.36Å; S190-E195 PolarHBondContact OG-OE2 3.41Å; D192-E195 HydrophobicContact CB-CB 4.26Å; D192-E195 PolarHBondContact O-N 3.34Å; D192-E195 VanDerWaalsContact O-N 3.1Å; E195-D197 VanDerWaalsContact C-N 3.33Å; E195-D197 PolarHBondContact O-N 2.92Å; E195-Y198 PolarHBondContact O-N 3.22Å; E195-L199 HydrophobicContact CG-CD1 4Å; E195-L199 HydrophobicContact CG-CG 4.38Å; E195-L199 WeakPolarHBondContact O-CB 3.47Å; E195-L199 VanDerWaalsContact O-CG 3.26Å; E195-L199 WeakPolarHBondContact O-CG 3.46Å; E195-L199 PolarHBondContact O-N 3.31Å
196	R	97.5	Very high	97	Very high	33 Å²	33	34.3 Å²	34.3	13%	0.125	16%	0.161	C	C	.	.	H	α-helix	trans	-61.2	-38.7	177.9	-60.5	-162.5	-57.2	-87.1	2.3	112.9	F188 S190 E191 D192 P193 L199 K200 E240	F188-R196 WeakPolarHBondContact O-CD 3.35Å; S190-R196 VanDerWaalsContact O-CD 3.29Å; S190-R196 WeakPolarHBondContact O-CD 3.47Å; S190-R196 PolarHBondContact O-NH1 3.41Å; E191-R196 VanDerWaalsContact C-NH1 3.28Å; E191-R196 PolarHBondContact O-NH1 2.93Å; D192-R196 PolarHBondContact O-N 3.35Å; P193-R196 PolarHBondContact O-N 2.95Å; R196-L199 PolarHBondContact O-N 3.48Å; R196-K200 WeakPolarHBondContact O-CB 3.15Å; R196-K200 PolarHBondContact O-N 3.16Å; R196-E240 HydrophobicContact CB-CG 3.97Å; R196-E240 IonicContact CZ-OE1 3.82Å; R196-E240 IonicContact NE-OE1 3.76Å; R196-E240 PolarHBondContact NE-OE1 2.94Å; R196-E240 IonicContact NE-OE2 3.27Å; R196-E240 IonicContact NH2-OE1 3.87Å; R196-E240 PolarHBondContact NH2-OE1 3.03Å
197	D	98.1	Very high	97	Very high	77 Å²	77	29.5 Å²	29.5	41%	0.412	14%	0.138	S	C	.	.	H	α-helix	trans	-66.5	-38.7	177.3	-170	61.8	0	0	0	112.8	P193 R194 E195 K200 T201	P193-D197 PolarHBondContact O-N 3.42Å; R194-D197 PolarHBondContact O-N 3.25Å; E195-D197 VanDerWaalsContact C-N 3.33Å; E195-D197 PolarHBondContact O-N 2.92Å; D197-K200 WeakPolarHBondContact O-CB 3.43Å; D197-K200 PolarHBondContact O-N 3.46Å; D197-K200 WeakPolarHBondContact OD1-CE 3.49Å; D197-K200 IonicContact OD1-NZ 3.78Å; D197-K200 PolarHBondContact OD1-NZ 3.44Å; D197-T201 PolarHBondContact O-N 3.39Å; D197-T201 PolarHBondContact O-OG1 3.27Å
198	Y	98.5	Very high	97	Very high	47 Å²	47	31.3 Å²	31.3	18%	0.184	16%	0.157	C	C	.	.	H	α-helix	trans	-66.4	-44.9	171.7	-85.2	-83.5	0	0	0	111.8	W148 Q152 Y155 E156 I159 R194 E195 K200 T201 V202	W148-Y198 AromaticContact CH2-CD2 3.7Å; W148-Y198 HydrophobicContact CH2-CD2 3.7Å; W148-Y198 AromaticContact CH2-CE2 4Å; W148-Y198 HydrophobicContact CH2-CE2 4Å; W148-Y198 HydrophobicContact CZ2-CD2 4.02Å; W148-Y198 AromaticContact CZ2-CE2 3.84Å; W148-Y198 HydrophobicContact CZ2-CE2 3.84Å; Q152-Y198 HydrophobicContact CG-CE2 4.27Å; Y155-Y198 HydrophobicContact CD2-CG 4.48Å; Y155-Y198 HydrophobicContact CG-CD1 4.26Å; Y155-Y198 HydrophobicContact CG-CG 4.09Å; E156-Y198 HydrophobicContact CB-CE1 4.3Å; I159-Y198 HydrophobicContact CD1-CD1 3.52Å; I159-Y198 HydrophobicContact CD1-CE1 4.06Å; R194-Y198 WeakPolarHBondContact O-CD2 3.47Å; R194-Y198 PolarHBondContact O-N 2.85Å; E195-Y198 PolarHBondContact O-N 3.22Å; Y198-K200 VanDerWaalsContact C-N 3.28Å; Y198-K200 PolarHBondContact O-N 2.92Å; Y198-T201 PolarHBondContact O-N 2.8Å; Y198-V202 WeakPolarHBondContact O-CG2 3.36Å; Y198-V202 PolarHBondContact O-N 3.18Å
199	L	98.6	Very high	96.9	Very high	0 Å²	0	34.5 Å²	34.5	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-58.2	-41.6	176.1	-72.9	168.6	0	0	0	111.7	Y155 L184 L187 F188 E195 R196 T201 V202 L203	Y155-L199 HydrophobicContact CE1-CD2 3.8Å; Y155-L199 HydrophobicContact CE1-CG 4.19Å; L184-L199 HydrophobicContact CD1-CD2 3.46Å; L184-L199 VanDerWaalsContact CD1-CD2 3.46Å; L184-L199 HydrophobicContact CG-CD2 4.14Å; L187-L199 VanDerWaalsContact C-CD1 3.41Å; L187-L199 HydrophobicContact CB-CD1 3.56Å; L187-L199 HydrophobicContact CB-CD2 3.93Å; L187-L199 HydrophobicContact CB-CG 4.41Å; L187-L199 HydrophobicContact CD1-CD2 4.09Å; L187-L199 VanDerWaalsContact O-CD1 3.23Å; L187-L199 WeakPolarHBondContact O-CD1 3.26Å; F188-L199 HydrophobicContact CD2-CB 4.11Å; F188-L199 HydrophobicContact CD2-CD1 4.33Å; F188-L199 HydrophobicContact CE1-CB 4.15Å; F188-L199 HydrophobicContact CE2-CB 3.71Å; F188-L199 VanDerWaalsContact CZ-C 3.45Å; F188-L199 HydrophobicContact CZ-CB 3.74Å; F188-L199 WeakPolarHBondContact CZ-O 3.35Å; E195-L199 HydrophobicContact CG-CD1 4Å; E195-L199 HydrophobicContact CG-CG 4.38Å; E195-L199 WeakPolarHBondContact O-CB 3.47Å; E195-L199 VanDerWaalsContact O-CG 3.26Å; E195-L199 WeakPolarHBondContact O-CG 3.46Å; E195-L199 PolarHBondContact O-N 3.31Å; R196-L199 PolarHBondContact O-N 3.48Å; L199-T201 VanDerWaalsContact C-N 3.34Å; L199-T201 PolarHBondContact O-N 3.18Å; L199-V202 PolarHBondContact O-N 3.46Å; L199-L203 VanDerWaalsContact O-CB 3.31Å; L199-L203 WeakPolarHBondContact O-CB 3.46Å; L199-L203 PolarHBondContact O-N 3.42Å
200	K	98.6	Very high	97	Very high	33 Å²	33	33 Å²	33	14%	0.143	16%	0.162	C	C	.	.	H	α-helix	trans	-53.2	-52.3	174.4	-176.9	-178.5	62.6	-173.9	0	111.1	F188 R196 D197 Y198 H204 E240 E243 I244	F188-K200 HydrophobicContact CE1-CB 4.45Å; R196-K200 WeakPolarHBondContact O-CB 3.15Å; R196-K200 PolarHBondContact O-N 3.16Å; D197-K200 WeakPolarHBondContact O-CB 3.43Å; D197-K200 PolarHBondContact O-N 3.46Å; D197-K200 WeakPolarHBondContact OD1-CE 3.49Å; D197-K200 IonicContact OD1-NZ 3.78Å; D197-K200 PolarHBondContact OD1-NZ 3.44Å; Y198-K200 VanDerWaalsContact C-N 3.28Å; Y198-K200 PolarHBondContact O-N 2.92Å; K200-H204 VanDerWaalsContact O-CB 3.3Å; K200-H204 WeakPolarHBondContact O-CB 3.45Å; K200-H204 PolarHBondContact O-N 3.16Å; K200-E240 HydrophobicContact CB-CB 4.16Å; K200-E240 HydrophobicContact CD-CB 4.14Å; K200-E240 HydrophobicContact CD-CG 4.37Å; K200-E240 HydrophobicContact CG-CB 4.3Å; K200-E243 HydrophobicContact CD-CB 3.94Å; K200-E243 HydrophobicContact CD-CG 4.44Å; K200-E243 VanDerWaalsContact NZ-CD 3.31Å; K200-E243 IonicContact NZ-OE1 3.37Å; K200-E243 PolarHBondContact NZ-OE1 3.03Å; K200-E243 VanDerWaalsContact NZ-OE1 3.17Å; K200-E243 IonicContact NZ-OE2 2.9Å; K200-E243 PolarHBondContact NZ-OE2 3.47Å; K200-I244 HydrophobicContact CB-CD1 4.47Å; K200-I244 HydrophobicContact CG-CD1 4.08Å; K200-I244 HydrophobicContact CG-CG1 3.72Å
201	T	98.4	Very high	97.1	Very high	40 Å²	40	38.4 Å²	38.4	25%	0.245	19%	0.19	C	C	.	.	H	α-helix	trans	-63.5	-47.8	179.8	-58.9	0	0	0	0	111.5	I159 D197 Y198 L199 H204 R205	I159-T201 HydrophobicContact CD1-CG2 3.72Å; I159-T201 HydrophobicContact CG1-CG2 4.2Å; I159-T201 HydrophobicContact CG2-CG2 4.33Å; D197-T201 PolarHBondContact O-N 3.39Å; D197-T201 PolarHBondContact O-OG1 3.27Å; Y198-T201 PolarHBondContact O-N 2.8Å; L199-T201 VanDerWaalsContact C-N 3.34Å; L199-T201 PolarHBondContact O-N 3.18Å; T201-H204 PolarHBondContact O-N 2.96Å; T201-R205 VanDerWaalsContact O-CG 3.32Å; T201-R205 WeakPolarHBondContact O-CG 3.27Å; T201-R205 PolarHBondContact O-N 3.4Å
202	V	98.5	Very high	97.3	Very high	0 Å²	0	40.3 Å²	40.3	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-59.1	-50.7	179.3	170.9	0	0	0	0	111.4	Y155 F158 I159 L162 L184 Y198 L199 H204 R205 I206	Y155-V202 HydrophobicContact CD1-CG2 4.38Å; F158-V202 HydrophobicContact CD1-CG1 3.62Å; F158-V202 HydrophobicContact CD1-CG2 4.02Å; F158-V202 HydrophobicContact CE1-CG1 3.43Å; F158-V202 VanDerWaalsContact CE1-CG1 3.43Å; I159-V202 HydrophobicContact CD1-CG2 4.24Å; I159-V202 HydrophobicContact CG1-CG2 3.64Å; L162-V202 HydrophobicContact CD1-CG1 4.07Å; L184-V202 HydrophobicContact CD1-CG1 4.26Å; L184-V202 HydrophobicContact CD2-CG1 3.9Å; Y198-V202 WeakPolarHBondContact O-CG2 3.36Å; Y198-V202 PolarHBondContact O-N 3.18Å; L199-V202 PolarHBondContact O-N 3.46Å; V202-H204 VanDerWaalsContact C-N 3.35Å; V202-H204 PolarHBondContact O-N 3.14Å; V202-R205 PolarHBondContact O-N 3.4Å; V202-I206 HydrophobicContact CG1-CD1 3.86Å; V202-I206 WeakPolarHBondContact O-CG1 3.4Å; V202-I206 PolarHBondContact O-N 2.85Å
203	L	98.7	Very high	97.5	Very high	0 Å²	0	41 Å²	41	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-64.1	-40.4	-178.8	-178.7	64.1	0	0	0	111.5	L184 L185 F188 L199 R205 I206 Y207 I217 I221 L241 I244	L184-L203 HydrophobicContact CD2-CB 4.35Å; L184-L203 HydrophobicContact CD2-CD1 4.26Å; L185-L203 HydrophobicContact CD2-CD1 4.45Å; L185-L203 HydrophobicContact CD2-CD2 3.54Å; F188-L203 HydrophobicContact CE2-CB 4.1Å; F188-L203 HydrophobicContact CE2-CD2 3.65Å; F188-L203 HydrophobicContact CE2-CG 4.48Å; F188-L203 HydrophobicContact CZ-CB 3.96Å; F188-L203 HydrophobicContact CZ-CD2 3.67Å; F188-L203 HydrophobicContact CZ-CG 4.47Å; L199-L203 VanDerWaalsContact O-CB 3.31Å; L199-L203 WeakPolarHBondContact O-CB 3.46Å; L199-L203 PolarHBondContact O-N 3.42Å; L203-R205 PolarHBondContact O-N 3.27Å; L203-I206 PolarHBondContact O-N 2.77Å; L203-Y207 WeakPolarHBondContact O-CB 3.31Å; L203-Y207 PolarHBondContact O-N 2.97Å; L203-I217 HydrophobicContact CD1-CD1 4.22Å; L203-I217 HydrophobicContact CD1-CG1 4.37Å; L203-I217 HydrophobicContact CD1-CG2 4.2Å; L203-I221 HydrophobicContact CD2-CD1 4.45Å; L203-L241 HydrophobicContact CD2-CD2 3.98Å; L203-I244 HydrophobicContact CB-CD1 4.09Å; L203-I244 HydrophobicContact CD2-CD1 3.74Å; L203-I244 HydrophobicContact CG-CD1 4.14Å
204	H	98.4	Very high	97.7	Very high	57 Å²	57	42.4 Å²	42.4	26%	0.264	22%	0.22	S	C	.	.	H	α-helix	trans	-61.3	-43.2	175.5	-177.3	-149.9	0	0	0	111.9	K200 T201 V202 Y207 G208 I244 S247	K200-H204 VanDerWaalsContact O-CB 3.3Å; K200-H204 WeakPolarHBondContact O-CB 3.45Å; K200-H204 PolarHBondContact O-N 3.16Å; T201-H204 PolarHBondContact O-N 2.96Å; V202-H204 VanDerWaalsContact C-N 3.35Å; V202-H204 PolarHBondContact O-N 3.14Å; H204-Y207 PolarHBondContact O-N 3.39Å; H204-G208 PolarHBondContact O-N 3.24Å; H204-I244 HydrophobicContact CB-CG1 4.42Å; H204-I244 HydrophobicContact CB-CG2 4.32Å; H204-S247 PolarHBondContact CE1-OG 3.17Å; H204-S247 PolarHBondContact NE2-OG 3.02Å
205	R	97.9	Very high	97.6	Very high	90 Å²	90	41.1 Å²	41.1	34%	0.34	23%	0.228	S	C	.	.	H	α-helix	trans	-64.1	-42.5	175.1	-66.2	-61.2	-177.3	-119.8	-0.5	112.1	L162 E163 T201 V202 L203 G208 K209	L162-R205 HydrophobicContact CB-CB 4.36Å; L162-R205 HydrophobicContact CD1-CB 4.26Å; E163-R205 HydrophobicContact CG-CG 4.43Å; E163-R205 IonicContact OE1-CZ 3.08Å; E163-R205 IonicContact OE1-NE 2.65Å; E163-R205 PolarHBondContact OE1-NE 2.91Å; E163-R205 IonicContact OE1-NH2 2.64Å; E163-R205 PolarHBondContact OE1-NH2 3.26Å; T201-R205 VanDerWaalsContact O-CG 3.32Å; T201-R205 WeakPolarHBondContact O-CG 3.27Å; T201-R205 PolarHBondContact O-N 3.4Å; V202-R205 PolarHBondContact O-N 3.4Å; L203-R205 PolarHBondContact O-N 3.27Å; R205-G208 PolarHBondContact O-N 3.36Å; R205-K209 WeakPolarHBondContact O-CG 3.31Å; R205-K209 PolarHBondContact O-N 3.45Å
206	I	98.3	Very high	97.7	Very high	0 Å²	0	42.7 Å²	42.7	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-60.7	-47.7	175.4	-69.6	171.5	0	0	0	110.3	F158 L162 I176 F180 V181 L184 V202 L203 G208 K209 F210 L213 I217	F158-I206 HydrophobicContact CE1-CD1 4.42Å; L162-I206 HydrophobicContact CD1-CG1 4.07Å; L162-I206 HydrophobicContact CD2-CG1 4.49Å; I176-I206 HydrophobicContact CG2-CD1 4.37Å; I176-I206 HydrophobicContact CG2-CG2 4.33Å; F180-I206 HydrophobicContact CE1-CD1 4.01Å; V181-I206 HydrophobicContact CG2-CG2 4.32Å; L184-I206 HydrophobicContact CD2-CD1 3.75Å; V202-I206 HydrophobicContact CG1-CD1 3.86Å; V202-I206 WeakPolarHBondContact O-CG1 3.4Å; V202-I206 PolarHBondContact O-N 2.85Å; L203-I206 PolarHBondContact O-N 2.77Å; I206-G208 VanDerWaalsContact C-N 3.29Å; I206-G208 PolarHBondContact O-N 3.13Å; I206-K209 PolarHBondContact O-N 3.16Å; I206-F210 HydrophobicContact CB-CD2 4.29Å; I206-F210 HydrophobicContact CG2-CD2 3.82Å; I206-F210 HydrophobicContact CG2-CE2 4.44Å; I206-F210 WeakPolarHBondContact O-CB 3.47Å; I206-F210 WeakPolarHBondContact O-CD2 3.43Å; I206-F210 PolarHBondContact O-N 3.07Å; I206-L213 HydrophobicContact CG2-CD1 4.12Å; I206-I217 HydrophobicContact CG2-CD1 4.22Å
207	Y	98.1	Very high	97.7	Very high	17 Å²	17	41.1 Å²	41.1	7%	0.067	23%	0.229	C	C	.	.	H	α-helix	trans	-59	-40.6	177.4	-175.4	-87.1	0	0	0	112.6	L203 H204 R214 I217 R218 I248	L203-Y207 WeakPolarHBondContact O-CB 3.31Å; L203-Y207 PolarHBondContact O-N 2.97Å; H204-Y207 PolarHBondContact O-N 3.39Å; Y207-R214 HydrophobicContact CD1-CG 4.31Å; Y207-R214 HydrophobicContact CD2-CB 4.17Å; Y207-R214 HydrophobicContact CD2-CG 3.89Å; Y207-R214 HydrophobicContact CE1-CG 4.03Å; Y207-R214 HydrophobicContact CE2-CB 3.56Å; Y207-R214 HydrophobicContact CE2-CG 3.6Å; Y207-R214 HydrophobicContact CG-CG 4.24Å; Y207-R214 WeakPolarHBondContact O-CG 3.27Å; Y207-R214 PolarHBondContact O-NE 3Å; Y207-I217 HydrophobicContact CD2-CB 4.12Å; Y207-I217 HydrophobicContact CD2-CD1 3.97Å; Y207-I217 HydrophobicContact CD2-CG2 3.99Å; Y207-R218 HydrophobicContact CE2-CG 4.1Å; Y207-R218 PolarHBondContact OH-NH1 2.93Å; Y207-I248 HydrophobicContact CD1-CD1 3.72Å; Y207-I248 HydrophobicContact CD1-CG1 3.69Å; Y207-I248 HydrophobicContact CD2-CD1 3.74Å; Y207-I248 HydrophobicContact CE1-CB 4.26Å; Y207-I248 HydrophobicContact CE1-CD1 3.66Å; Y207-I248 HydrophobicContact CE1-CG1 3.44Å; Y207-I248 VanDerWaalsContact CE1-CG1 3.44Å; Y207-I248 HydrophobicContact CE1-CG2 3.97Å; Y207-I248 HydrophobicContact CE2-CD1 3.66Å; Y207-I248 HydrophobicContact CE2-CG1 4.37Å; Y207-I248 HydrophobicContact CG-CD1 3.77Å; Y207-I248 HydrophobicContact CG-CG1 4.26Å; Y207-I248 VanDerWaalsContact OH-CG2 3.27Å; Y207-I248 WeakPolarHBondContact OH-CG2 3.25Å
208	G	96.4	Very high	97.7	Very high	38 Å²	38	39.2 Å²	39.2	39%	0.392	22%	0.216	S	C	.	.	H	α-helix	trans	-62.6	-50.2	176.7	0	0	0	0	0	112.8	H204 R205 I206 R214	H204-G208 PolarHBondContact O-N 3.24Å; R205-G208 PolarHBondContact O-N 3.36Å; I206-G208 VanDerWaalsContact C-N 3.29Å; I206-G208 PolarHBondContact O-N 3.13Å; G208-R214 PolarHBondContact O-NH2 3.13Å
209	K	96.5	Very high	97.7	Very high	68 Å²	68	43.2 Å²	43.2	30%	0.296	23%	0.234	S	C	.	.	H	α-helix	trans	-83.1	-28.1	-171.9	-65.6	-162.9	174.7	-146.9	0	114.7	L162 F167 P169 R205 I206	L162-K209 WeakPolarHBondContact O-CD 3.3Å; L162-K209 WeakPolarHBondContact O-CE 3.34Å; L162-K209 PolarHBondContact O-NZ 3.14Å; F167-K209 HydrophobicContact CD1-CD 3.67Å; F167-K209 HydrophobicContact CE1-CB 4.48Å; F167-K209 HydrophobicContact CE1-CD 3.79Å; P169-K209 HydrophobicContact CG-CB 4.36Å; R205-K209 WeakPolarHBondContact O-CG 3.31Å; R205-K209 PolarHBondContact O-N 3.45Å; I206-K209 PolarHBondContact O-N 3.16Å
210	F	97.2	Very high	97.6	Very high	10 Å²	10	45 Å²	45	4%	0.044	24%	0.242	C	C	.	.			trans	-110.1	85.9	-175.5	-63	-82.6	0	0	0	112.2	F167 P169 A172 K173 I176 I206 G212 L213	F167-F210 HydrophobicContact CE1-CE2 4.3Å; F167-F210 HydrophobicContact CE1-CZ 4.02Å; F167-F210 HydrophobicContact CZ-CE2 4.09Å; F167-F210 AromaticContact CZ-CZ 3.71Å; F167-F210 HydrophobicContact CZ-CZ 3.71Å; P169-F210 HydrophobicContact CB-CD1 4.35Å; P169-F210 HydrophobicContact CB-CE1 4.13Å; A172-F210 HydrophobicContact CB-CE1 3.91Å; A172-F210 HydrophobicContact CB-CZ 3.63Å; K173-F210 HydrophobicContact CB-CD1 4.2Å; K173-F210 HydrophobicContact CB-CE1 4.07Å; I176-F210 HydrophobicContact CB-CE2 4.5Å; I176-F210 HydrophobicContact CB-CZ 4.19Å; I176-F210 HydrophobicContact CD1-CE2 4.03Å; I176-F210 HydrophobicContact CD1-CZ 3.88Å; I176-F210 HydrophobicContact CG2-CE2 4.22Å; I176-F210 HydrophobicContact CG2-CZ 4.39Å; I206-F210 HydrophobicContact CB-CD2 4.29Å; I206-F210 HydrophobicContact CG2-CD2 3.82Å; I206-F210 HydrophobicContact CG2-CE2 4.44Å; I206-F210 WeakPolarHBondContact O-CB 3.47Å; I206-F210 WeakPolarHBondContact O-CD2 3.43Å; I206-F210 PolarHBondContact O-N 3.07Å; F210-G212 PolarHBondContact O-N 3.24Å; F210-G212 VanDerWaalsContact O-N 3.17Å; F210-L213 HydrophobicContact CB-CB 4.07Å; F210-L213 HydrophobicContact CB-CD1 3.71Å; F210-L213 HydrophobicContact CB-CG 3.95Å; F210-L213 HydrophobicContact CD1-CD1 4.49Å; F210-L213 HydrophobicContact CD2-CD1 4.44Å; F210-L213 HydrophobicContact CG-CD1 3.99Å; F210-L213 PolarHBondContact O-N 3.48Å
211	L	95.5	Very high	97.6	Very high	122 Å²	122	43.4 Å²	43.4	64%	0.639	24%	0.235	S	C	*	.	G	3₁₀ helix	trans	-54.1	-38.3	179.5	-58	-175.6	0	0	0	113.2	L213 R214	L211-L213 VanDerWaalsContact C-N 3.26Å; L211-L213 PolarHBondContact O-N 3.12Å; L211-R214 VanDerWaalsContact CD2-NH2 3.28Å; L211-R214 PolarHBondContact O-N 3.35Å
212	G	96.5	Very high	97.6	Very high	71 Å²	71	43.3 Å²	43.3	73%	0.732	23%	0.234	S	C	*	.	G	3₁₀ helix	trans	-68.3	-18.5	179.7	0	0	0	0	0	114.9	F210	F210-G212 PolarHBondContact O-N 3.24Å; F210-G212 VanDerWaalsContact O-N 3.17Å
213	L	97.7	Very high	97.6	Very high	16 Å²	16	46.8 Å²	46.8	8%	0.084	25%	0.252	C	S	.	.	G	3₁₀ helix	trans	-93.4	-13.4	178.3	-64.4	177.2	0	0	0	112.8	I176 Q178 V181 I206 F210 L211 A215 F216 I217	I176-L213 HydrophobicContact CG2-CD1 4.19Å; Q178-L213 HydrophobicContact CG-CD2 4.1Å; V181-L213 HydrophobicContact CG2-CD1 3.95Å; I206-L213 HydrophobicContact CG2-CD1 4.12Å; F210-L213 HydrophobicContact CB-CB 4.07Å; F210-L213 HydrophobicContact CB-CD1 3.71Å; F210-L213 HydrophobicContact CB-CG 3.95Å; F210-L213 HydrophobicContact CD1-CD1 4.49Å; F210-L213 HydrophobicContact CD2-CD1 4.44Å; F210-L213 HydrophobicContact CG-CD1 3.99Å; F210-L213 PolarHBondContact O-N 3.48Å; L211-L213 VanDerWaalsContact C-N 3.26Å; L211-L213 PolarHBondContact O-N 3.12Å; L213-A215 PolarHBondContact O-N 3.47Å; L213-F216 WeakPolarHBondContact O-CB 3.49Å; L213-F216 PolarHBondContact O-N 3.47Å; L213-F216 VanDerWaalsContact O-N 3.11Å; L213-I217 HydrophobicContact CB-CD1 4.06Å; L213-I217 WeakPolarHBondContact O-CG1 3.49Å; L213-I217 PolarHBondContact O-N 3.11Å
214	R	97.4	Very high	97.5	Very high	84 Å²	84	47.8 Å²	47.8	32%	0.317	26%	0.257	S	S	.	.	H	α-helix	trans	-56.9	-47.5	-173.4	-69.6	-173.6	174.1	-178.3	2.1	113.5	Y207 G208 L211 F216 I217 R218	Y207-R214 HydrophobicContact CD1-CG 4.31Å; Y207-R214 HydrophobicContact CD2-CB 4.17Å; Y207-R214 HydrophobicContact CD2-CG 3.89Å; Y207-R214 HydrophobicContact CE1-CG 4.03Å; Y207-R214 HydrophobicContact CE2-CB 3.56Å; Y207-R214 HydrophobicContact CE2-CG 3.6Å; Y207-R214 HydrophobicContact CG-CG 4.24Å; Y207-R214 WeakPolarHBondContact O-CG 3.27Å; Y207-R214 PolarHBondContact O-NE 3Å; G208-R214 PolarHBondContact O-NH2 3.13Å; L211-R214 VanDerWaalsContact CD2-NH2 3.28Å; L211-R214 PolarHBondContact O-N 3.35Å; R214-F216 VanDerWaalsContact C-N 3.31Å; R214-F216 PolarHBondContact O-N 2.86Å; R214-I217 PolarHBondContact O-N 3.33Å; R214-R218 WeakPolarHBondContact O-CG 2.98Å; R214-R218 PolarHBondContact O-N 3.06Å
215	A	96.5	Very high	97.5	Very high	61 Å²	61	45 Å²	45	50%	0.504	25%	0.245	S	C	.	.	H	α-helix	trans	-64.1	-39.3	179.6	0	0	0	0	0	111.7	L213 K219	L213-A215 PolarHBondContact O-N 3.47Å; A215-K219 WeakPolarHBondContact O-CB 3.34Å; A215-K219 PolarHBondContact O-N 2.86Å
216	F	98.1	Very high	97.5	Very high	32 Å²	32	43.8 Å²	43.8	14%	0.14	24%	0.244	C	C	.	.	H	α-helix	trans	-65.9	-48.6	177.2	-178.6	-97	0	0	0	111.5	Q178 V181 L213 R214 R218 K219 Q220	Q178-F216 HydrophobicContact CB-CD1 4.1Å; Q178-F216 HydrophobicContact CB-CD2 4.24Å; Q178-F216 HydrophobicContact CB-CE1 3.78Å; Q178-F216 HydrophobicContact CB-CE2 3.93Å; Q178-F216 HydrophobicContact CB-CG 4.32Å; Q178-F216 HydrophobicContact CB-CZ 3.69Å; Q178-F216 VanDerWaalsContact CD-CD2 3.49Å; Q178-F216 HydrophobicContact CG-CB 4.37Å; Q178-F216 HydrophobicContact CG-CD1 3.93Å; Q178-F216 HydrophobicContact CG-CD2 3.83Å; Q178-F216 HydrophobicContact CG-CE1 4.14Å; Q178-F216 HydrophobicContact CG-CE2 4.03Å; Q178-F216 HydrophobicContact CG-CG 3.77Å; Q178-F216 HydrophobicContact CG-CZ 4.19Å; Q178-F216 VanDerWaalsContact O-CE1 3.31Å; Q178-F216 WeakPolarHBondContact O-CE1 3.37Å; V181-F216 HydrophobicContact CB-CD1 4.37Å; V181-F216 HydrophobicContact CB-CE1 4.17Å; V181-F216 HydrophobicContact CG1-CD1 4Å; V181-F216 HydrophobicContact CG1-CE1 3.97Å; L213-F216 WeakPolarHBondContact O-CB 3.49Å; L213-F216 PolarHBondContact O-N 3.47Å; L213-F216 VanDerWaalsContact O-N 3.11Å; R214-F216 VanDerWaalsContact C-N 3.31Å; R214-F216 PolarHBondContact O-N 2.86Å; F216-R218 PolarHBondContact O-N 3.33Å; F216-K219 PolarHBondContact O-N 3.32Å; F216-K219 VanDerWaalsContact O-N 3.17Å; F216-Q220 HydrophobicContact CD1-CG 4.08Å; F216-Q220 HydrophobicContact CD2-CG 4.46Å; F216-Q220 HydrophobicContact CE1-CG 3.64Å; F216-Q220 HydrophobicContact CE2-CG 4.08Å; F216-Q220 VanDerWaalsContact CE2-NE2 3.25Å; F216-Q220 HydrophobicContact CG-CG 4.46Å; F216-Q220 HydrophobicContact CZ-CG 3.64Å; F216-Q220 WeakPolarHBondContact O-CG 3.4Å; F216-Q220 PolarHBondContact O-N 3.24Å
217	I	98.4	Very high	97.5	Very high	0 Å²	0	49.2 Å²	49.2	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-56.1	-50.9	177.7	-69.2	165.1	0	0	0	110.6	V181 L203 I206 Y207 L213 R214 K219 Q220 I221	V181-I217 HydrophobicContact CG1-CD1 4.48Å; V181-I217 HydrophobicContact CG1-CG1 3.63Å; L203-I217 HydrophobicContact CD1-CD1 4.22Å; L203-I217 HydrophobicContact CD1-CG1 4.37Å; L203-I217 HydrophobicContact CD1-CG2 4.2Å; I206-I217 HydrophobicContact CG2-CD1 4.22Å; Y207-I217 HydrophobicContact CD2-CB 4.12Å; Y207-I217 HydrophobicContact CD2-CD1 3.97Å; Y207-I217 HydrophobicContact CD2-CG2 3.99Å; L213-I217 HydrophobicContact CB-CD1 4.06Å; L213-I217 WeakPolarHBondContact O-CG1 3.49Å; L213-I217 PolarHBondContact O-N 3.11Å; R214-I217 PolarHBondContact O-N 3.33Å; I217-K219 VanDerWaalsContact C-N 3.32Å; I217-K219 PolarHBondContact O-N 2.72Å; I217-Q220 PolarHBondContact O-N 3.37Å; I217-I221 HydrophobicContact CG2-CD1 3.76Å; I217-I221 HydrophobicContact CG2-CG1 4.4Å; I217-I221 WeakPolarHBondContact O-CG1 3.22Å; I217-I221 PolarHBondContact O-N 2.86Å
218	R	97.9	Very high	97.4	Very high	38 Å²	38	48.5 Å²	48.5	14%	0.143	26%	0.262	C	S	.	.	H	α-helix	trans	-58.2	-44.3	177.7	-69.5	-167.9	-56.4	-99.8	6.8	111.7	Y207 R214 F216 Q220 I221 N222 E259	Y207-R218 HydrophobicContact CE2-CG 4.1Å; Y207-R218 PolarHBondContact OH-NH1 2.93Å; R214-R218 WeakPolarHBondContact O-CG 2.98Å; R214-R218 PolarHBondContact O-N 3.06Å; F216-R218 PolarHBondContact O-N 3.33Å; R218-Q220 PolarHBondContact O-N 2.99Å; R218-I221 PolarHBondContact O-N 3.4Å; R218-N222 WeakPolarHBondContact O-CB 3.5Å; R218-N222 PolarHBondContact O-N 2.92Å; R218-N222 PolarHBondContact O-OD1 3.12Å; R218-E259 IonicContact NH2-OE1 3.3Å; R218-E259 PolarHBondContact NH2-OE1 2.88Å
219	K	97.5	Very high	97.4	Very high	131 Å²	131	47.4 Å²	47.4	57%	0.57	25%	0.247	S	C	*	.	H	α-helix	trans	-61.3	-42.6	177.8	-175.4	179.1	179.1	-178.2	0	112.1	A215 F216 I217 N222 N223	A215-K219 WeakPolarHBondContact O-CB 3.34Å; A215-K219 PolarHBondContact O-N 2.86Å; F216-K219 PolarHBondContact O-N 3.32Å; F216-K219 VanDerWaalsContact O-N 3.17Å; I217-K219 VanDerWaalsContact C-N 3.32Å; I217-K219 PolarHBondContact O-N 2.72Å; K219-N222 WeakPolarHBondContact O-CB 3.35Å; K219-N222 PolarHBondContact O-N 3.43Å; K219-N223 VanDerWaalsContact O-CG 3.25Å; K219-N223 PolarHBondContact O-N 2.85Å; K219-N223 PolarHBondContact O-ND2 3.38Å; K219-N223 PolarHBondContact O-OD1 3.16Å
220	Q	98.2	Very high	97.4	Very high	36 Å²	36	51.1 Å²	51.1	17%	0.168	26%	0.261	C	S	.	.	H	α-helix	trans	-70.6	-40.3	179.9	-64	-51.9	-24.6	0	0	112.5	L185 F216 I217 R218 N222 N223 I224	L185-Q220 HydrophobicContact CD1-CB 3.47Å; L185-Q220 VanDerWaalsContact CD1-CB 3.47Å; L185-Q220 HydrophobicContact CD1-CG 4.24Å; F216-Q220 HydrophobicContact CD1-CG 4.08Å; F216-Q220 HydrophobicContact CD2-CG 4.46Å; F216-Q220 HydrophobicContact CE1-CG 3.64Å; F216-Q220 HydrophobicContact CE2-CG 4.08Å; F216-Q220 VanDerWaalsContact CE2-NE2 3.25Å; F216-Q220 HydrophobicContact CG-CG 4.46Å; F216-Q220 HydrophobicContact CZ-CG 3.64Å; F216-Q220 WeakPolarHBondContact O-CG 3.4Å; F216-Q220 PolarHBondContact O-N 3.24Å; I217-Q220 PolarHBondContact O-N 3.37Å; R218-Q220 PolarHBondContact O-N 2.99Å; Q220-N222 VanDerWaalsContact C-N 3.28Å; Q220-N222 PolarHBondContact O-N 3.46Å; Q220-N223 WeakPolarHBondContact O-CB 3.26Å; Q220-N223 PolarHBondContact O-N 2.68Å; Q220-N223 VanDerWaalsContact O-N 3.15Å; Q220-N223 PolarHBondContact OE1-ND2 3.39Å; Q220-I224 WeakPolarHBondContact O-CG1 3.48Å; Q220-I224 PolarHBondContact O-N 3.38Å
221	I	98.4	Very high	97.4	Very high	0 Å²	0	57.8 Å²	57.8	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-60.1	-41.9	172.6	-65.6	172.5	0	0	0	110.4	L185 L203 I217 R218 N223 I224 F225 L241 L245	L185-I221 HydrophobicContact CD2-CG1 4.08Å; L203-I221 HydrophobicContact CD2-CD1 4.45Å; I217-I221 HydrophobicContact CG2-CD1 3.76Å; I217-I221 HydrophobicContact CG2-CG1 4.4Å; I217-I221 WeakPolarHBondContact O-CG1 3.22Å; I217-I221 PolarHBondContact O-N 2.86Å; R218-I221 PolarHBondContact O-N 3.4Å; I221-N223 VanDerWaalsContact C-N 3.33Å; I221-N223 PolarHBondContact O-N 3.13Å; I221-I224 PolarHBondContact O-N 3Å; I221-F225 HydrophobicContact CG2-CD2 4.02Å; I221-F225 HydrophobicContact CG2-CE1 4.28Å; I221-F225 HydrophobicContact CG2-CE2 3.68Å; I221-F225 HydrophobicContact CG2-CG 4.49Å; I221-F225 HydrophobicContact CG2-CZ 3.82Å; I221-F225 PolarHBondContact O-N 3.42Å; I221-L241 HydrophobicContact CD1-CD2 4.21Å; I221-L241 HydrophobicContact CG1-CD2 4.21Å; I221-L241 HydrophobicContact CG2-CD1 4.4Å; I221-L245 HydrophobicContact CG2-CD1 3.75Å; I221-L245 HydrophobicContact CG2-CG 4.4Å
222	N	97.5	Very high	97.2	Very high	39 Å²	39	55.2 Å²	55.2	21%	0.209	28%	0.282	C	S	.	.	H	α-helix	trans	-58.8	-44.6	174.6	-67.6	1.8	0	0	0	111.9	R218 K219 Q220 I224 F225 L226 F263	R218-N222 WeakPolarHBondContact O-CB 3.5Å; R218-N222 PolarHBondContact O-N 2.92Å; R218-N222 PolarHBondContact O-OD1 3.12Å; K219-N222 WeakPolarHBondContact O-CB 3.35Å; K219-N222 PolarHBondContact O-N 3.43Å; Q220-N222 VanDerWaalsContact C-N 3.28Å; Q220-N222 PolarHBondContact O-N 3.46Å; N222-I224 VanDerWaalsContact C-N 3.33Å; N222-I224 PolarHBondContact O-N 3.26Å; N222-F225 PolarHBondContact O-N 2.99Å; N222-L226 WeakPolarHBondContact O-CB 3.35Å; N222-L226 VanDerWaalsContact O-CG 3.26Å; N222-L226 WeakPolarHBondContact O-CG 3.5Å; N222-L226 PolarHBondContact O-N 3.11Å; N222-F263 WeakPolarHBondContact OD1-CD2 3.31Å; N222-F263 WeakPolarHBondContact OD1-CE2 3.31Å
223	N	97.7	Very high	96.9	Very high	72 Å²	72	55.4 Å²	55.4	39%	0.385	26%	0.263	S	S	.	.	H	α-helix	trans	-61.9	-42.2	177.7	-66.1	-20.8	0	0	0	111.6	K219 Q220 I221 L226 R227	K219-N223 VanDerWaalsContact O-CG 3.25Å; K219-N223 PolarHBondContact O-N 2.85Å; K219-N223 PolarHBondContact O-ND2 3.38Å; K219-N223 PolarHBondContact O-OD1 3.16Å; Q220-N223 WeakPolarHBondContact O-CB 3.26Å; Q220-N223 PolarHBondContact O-N 2.68Å; Q220-N223 VanDerWaalsContact O-N 3.15Å; Q220-N223 PolarHBondContact OE1-ND2 3.39Å; I221-N223 VanDerWaalsContact C-N 3.33Å; I221-N223 PolarHBondContact O-N 3.13Å; N223-L226 PolarHBondContact O-N 3.05Å; N223-R227 WeakPolarHBondContact O-CB 3.47Å; N223-R227 PolarHBondContact O-N 3.16Å
224	I	98.1	Very high	96.6	Very high	21 Å²	21	57.6 Å²	57.6	11%	0.108	27%	0.273	C	S	.	.	H	α-helix	trans	-59.3	-49	176.3	-69.3	166.5	0	0	0	110.1	L185 Q220 I221 N222 R227 F228 F235 L241	L185-I224 HydrophobicContact CB-CD1 4.17Å; L185-I224 HydrophobicContact CD2-CD1 4.34Å; Q220-I224 WeakPolarHBondContact O-CG1 3.48Å; Q220-I224 PolarHBondContact O-N 3.38Å; I221-I224 PolarHBondContact O-N 3Å; N222-I224 VanDerWaalsContact C-N 3.33Å; N222-I224 PolarHBondContact O-N 3.26Å; I224-R227 PolarHBondContact O-N 3.15Å; I224-F228 WeakPolarHBondContact O-CB 3.46Å; I224-F228 PolarHBondContact O-N 3.38Å; I224-F235 HydrophobicContact CD1-CZ 4.5Å; I224-F235 HydrophobicContact CG2-CD1 3.95Å; I224-F235 HydrophobicContact CG2-CD2 4.06Å; I224-F235 HydrophobicContact CG2-CE1 3.77Å; I224-F235 HydrophobicContact CG2-CE2 3.86Å; I224-F235 HydrophobicContact CG2-CG 4.08Å; I224-F235 HydrophobicContact CG2-CZ 3.7Å; I224-L241 HydrophobicContact CD1-CD1 4.44Å; I224-L241 HydrophobicContact CG2-CD1 4.2Å
225	F	98.4	Very high	96.5	Very high	0 Å²	0	54.4 Å²	54.4	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-65.4	-40.1	179.2	-69.9	-14.9	0	0	0	113.2	I221 N222 F228 V229 V238 L241 L242 L245 F263 V267 L271	I221-F225 HydrophobicContact CG2-CD2 4.02Å; I221-F225 HydrophobicContact CG2-CE1 4.28Å; I221-F225 HydrophobicContact CG2-CE2 3.68Å; I221-F225 HydrophobicContact CG2-CG 4.49Å; I221-F225 HydrophobicContact CG2-CZ 3.82Å; I221-F225 PolarHBondContact O-N 3.42Å; N222-F225 PolarHBondContact O-N 2.99Å; F225-F228 PolarHBondContact O-N 3Å; F225-V229 WeakPolarHBondContact O-CB 3.35Å; F225-V229 VanDerWaalsContact O-CG2 3.3Å; F225-V229 WeakPolarHBondContact O-CG2 3.19Å; F225-V229 PolarHBondContact O-N 3Å; F225-V238 HydrophobicContact CE1-CG1 4.11Å; F225-L241 HydrophobicContact CE1-CB 3.98Å; F225-L241 HydrophobicContact CE1-CD1 3.99Å; F225-L241 HydrophobicContact CZ-CB 3.82Å; F225-L242 HydrophobicContact CE2-CD2 3.93Å; F225-L242 HydrophobicContact CE2-CG 4.45Å; F225-L242 HydrophobicContact CZ-CD2 3.94Å; F225-L242 HydrophobicContact CZ-CG 3.96Å; F225-L245 HydrophobicContact CD2-CD1 4.42Å; F225-L245 HydrophobicContact CE2-CD1 3.34Å; F225-L245 HydrophobicContact CZ-CD1 3.82Å; F225-F263 HydrophobicContact CD2-CE2 4.41Å; F225-V267 HydrophobicContact CB-CG1 3.51Å; F225-V267 HydrophobicContact CD2-CG1 3.74Å; F225-V267 HydrophobicContact CG-CG1 4.15Å; F225-L271 HydrophobicContact CB-CD2 4.44Å; F225-L271 HydrophobicContact CD2-CD1 3.91Å; F225-L271 HydrophobicContact CE2-CD1 4.1Å; F225-L271 HydrophobicContact CG-CD1 4.2Å; F225-L271 HydrophobicContact CG-CD2 4.46Å
226	L	97.5	Very high	96.3	Very high	63 Å²	63	53 Å²	53	33%	0.33	25%	0.246	S	C	.	.	H	α-helix	trans	-63.2	-44.2	176.1	-71.2	172.8	0	0	0	111.3	N222 N223 V229 Y230 V267	N222-L226 WeakPolarHBondContact O-CB 3.35Å; N222-L226 VanDerWaalsContact O-CG 3.26Å; N222-L226 WeakPolarHBondContact O-CG 3.5Å; N222-L226 PolarHBondContact O-N 3.11Å; N223-L226 PolarHBondContact O-N 3.05Å; L226-V229 PolarHBondContact O-N 3.14Å; L226-Y230 HydrophobicContact CD2-CD2 4.06Å; L226-Y230 HydrophobicContact CD2-CE2 3.66Å; L226-Y230 WeakPolarHBondContact O-CB 3.38Å; L226-Y230 VanDerWaalsContact O-CD2 3.3Å; L226-Y230 WeakPolarHBondContact O-CD2 3.35Å; L226-Y230 PolarHBondContact O-N 3.06Å; L226-V267 HydrophobicContact CD2-CG2 4.22Å; L226-V267 HydrophobicContact CG-CG2 4.43Å
227	R	97.5	Very high	96.2	Very high	114 Å²	114	51.5 Å²	51.5	43%	0.43	24%	0.239	S	C	.	.	H	α-helix	trans	-61.8	-44.5	174.5	-174.4	178.1	70.3	176.8	3.8	111.4	N223 I224 E231 T232	N223-R227 WeakPolarHBondContact O-CB 3.47Å; N223-R227 PolarHBondContact O-N 3.16Å; I224-R227 PolarHBondContact O-N 3.15Å; R227-E231 HydrophobicContact CG-CB 4.1Å; R227-E231 HydrophobicContact CG-CG 4.46Å; R227-E231 WeakPolarHBondContact O-CA 3.45Å; R227-E231 VanDerWaalsContact O-CB 3.29Å; R227-E231 WeakPolarHBondContact O-CB 3.47Å; R227-E231 PolarHBondContact O-N 3.11Å; R227-T232 HydrophobicContact CG-CG2 4.12Å; R227-T232 PolarHBondContact O-N 3.2Å
228	F	96.6	Very high	96.2	Very high	3 Å²	3	51.6 Å²	51.6	1%	0.013	24%	0.24	C	C	.	.	I	π-helix	trans	-58.8	-48.8	176.9	171	-114	0	0	0	111.9	I224 F225 E233 F235 V238 L271 V274 F280	I224-F228 WeakPolarHBondContact O-CB 3.46Å; I224-F228 PolarHBondContact O-N 3.38Å; F225-F228 PolarHBondContact O-N 3Å; F228-E233 VanDerWaalsContact CE2-C 3.49Å; F228-E233 WeakPolarHBondContact O-CA 3.32Å; F228-E233 PolarHBondContact O-N 3.32Å; F228-F235 HydrophobicContact CB-CB 4.43Å; F228-F235 HydrophobicContact CD2-CB 3.84Å; F228-F235 HydrophobicContact CE2-CB 4.49Å; F228-F235 HydrophobicContact CG-CB 4.34Å; F228-V238 HydrophobicContact CD1-CG2 3.97Å; F228-V238 HydrophobicContact CD2-CG2 4.34Å; F228-V238 HydrophobicContact CE1-CG1 4.44Å; F228-V238 HydrophobicContact CE1-CG2 3.85Å; F228-V238 HydrophobicContact CE2-CG2 4.24Å; F228-V238 HydrophobicContact CG-CG2 4.22Å; F228-V238 HydrophobicContact CZ-CG2 4Å; F228-L271 HydrophobicContact CD1-CD2 3.67Å; F228-L271 HydrophobicContact CE1-CD2 3.88Å; F228-V274 HydrophobicContact CD1-CG1 4.44Å; F228-V274 HydrophobicContact CE1-CB 4.28Å; F228-V274 HydrophobicContact CE1-CG1 3.94Å; F228-V274 HydrophobicContact CE1-CG2 3.82Å; F228-V274 HydrophobicContact CZ-CB 4.26Å; F228-V274 HydrophobicContact CZ-CG1 4.26Å; F228-V274 HydrophobicContact CZ-CG2 3.91Å; F228-F280 HydrophobicContact CE1-CE1 4.07Å; F228-F280 AromaticContact CE1-CZ 3.97Å; F228-F280 HydrophobicContact CE1-CZ 3.97Å; F228-F280 AromaticContact CZ-CE1 3.98Å; F228-F280 HydrophobicContact CZ-CE1 3.98Å; F228-F280 HydrophobicContact CZ-CZ 4.29Å
229	V	97	Very high	96.2	Very high	14 Å²	14	50.5 Å²	50.5	9%	0.085	24%	0.239	C	C	.	.	I	π-helix	trans	-71.2	-41.1	-176.7	173.8	0	0	0	0	112.8	F225 L226 P270 L271 V274	F225-V229 WeakPolarHBondContact O-CB 3.35Å; F225-V229 VanDerWaalsContact O-CG2 3.3Å; F225-V229 WeakPolarHBondContact O-CG2 3.19Å; F225-V229 PolarHBondContact O-N 3Å; L226-V229 PolarHBondContact O-N 3.14Å; V229-P270 HydrophobicContact CG1-CB 4.17Å; V229-L271 HydrophobicContact CG2-CD2 3.48Å; V229-L271 VanDerWaalsContact CG2-CD2 3.48Å; V229-L271 HydrophobicContact CG2-CG 4.03Å; V229-V274 HydrophobicContact CB-CG1 4.43Å; V229-V274 HydrophobicContact CG2-CG1 4.11Å
230	Y	96.6	Very high	96.2	Very high	147 Å²	147	45.2 Å²	45.2	58%	0.576	22%	0.216	S	C	*	.	I	π-helix	trans	-107.3	-15.6	-167.1	-61.7	-65.6	0	0	0	115	L226 P270	L226-Y230 HydrophobicContact CD2-CD2 4.06Å; L226-Y230 HydrophobicContact CD2-CE2 3.66Å; L226-Y230 WeakPolarHBondContact O-CB 3.38Å; L226-Y230 VanDerWaalsContact O-CD2 3.3Å; L226-Y230 WeakPolarHBondContact O-CD2 3.35Å; L226-Y230 PolarHBondContact O-N 3.06Å; Y230-P270 WeakPolarHBondContact OH-CB 3.38Å
231	E	96.4	Very high	96.3	Very high	149 Å²	149	43.5 Å²	43.5	70%	0.696	21%	0.208	S	C	*	.	I	π-helix	trans	-120.7	-54.5	-173.5	-58.1	176.5	-146.5	0	0	112.9	R227	R227-E231 HydrophobicContact CG-CB 4.1Å; R227-E231 HydrophobicContact CG-CG 4.46Å; R227-E231 WeakPolarHBondContact O-CA 3.45Å; R227-E231 VanDerWaalsContact O-CB 3.29Å; R227-E231 WeakPolarHBondContact O-CB 3.47Å; R227-E231 PolarHBondContact O-N 3.11Å
232	T	91.8	Very high	96.3	Very high	69 Å²	69	43.5 Å²	43.5	42%	0.423	21%	0.208	S	C	.	.	I	π-helix	trans	-106	-30.2	-166.8	62.8	0	0	0	0	114.9	R227 H234	R227-T232 HydrophobicContact CG-CG2 4.12Å; R227-T232 PolarHBondContact O-N 3.2Å; T232-H234 PolarHBondContact O-N 3.45Å; T232-H234 PolarHBondContact OG1-N 2.67Å; T232-H234 PolarHBondContact OG1-O 3.48Å
233	E	90.8	Very high	96.3	Very high	75 Å²	75	45.4 Å²	45.4	35%	0.35	22%	0.216	S	C	.	.	S	Bend	trans	48	20.1	-164.3	-67.5	-158.5	114.2	0	0	113.8	F228 R275	F228-E233 VanDerWaalsContact CE2-C 3.49Å; F228-E233 WeakPolarHBondContact O-CA 3.32Å; F228-E233 PolarHBondContact O-N 3.32Å; E233-R275 IonicContact OE2-CZ 2.82Å; E233-R275 IonicContact OE2-NE 2.73Å; E233-R275 PolarHBondContact OE2-NE 3.15Å; E233-R275 IonicContact OE2-NH2 3.91Å
234	H	90.7	Very high	96.4	Very high	62 Å²	62	42.2 Å²	42.2	29%	0.287	20%	0.198	S	C	.	.			trans	-135.2	121.1	-180	-175.6	73.1	0	0	0	110.3	S130 T232	S130-H234 PolarHBondContact OG-NE2 2.9Å; T232-H234 PolarHBondContact O-N 3.45Å; T232-H234 PolarHBondContact OG1-N 2.67Å; T232-H234 PolarHBondContact OG1-O 3.48Å
235	F	94.1	Very high	96.4	Very high	16 Å²	16	41.4 Å²	41.4	7%	0.07	19%	0.194	C	C	.	.			trans	-169.3	124.1	168.2	-173.2	-104.6	0	0	0	108.3	F188 D189 I224 F228 V238 L241	F188-F235 HydrophobicContact CB-CE1 4.11Å; F188-F235 HydrophobicContact CB-CZ 3.63Å; D189-F235 HydrophobicContact CB-CD2 3.96Å; D189-F235 HydrophobicContact CB-CE2 3.73Å; D189-F235 VanDerWaalsContact OD1-CA 3.26Å; D189-F235 WeakPolarHBondContact OD1-CA 3.21Å; D189-F235 WeakPolarHBondContact OD1-CD2 3.22Å; I224-F235 HydrophobicContact CD1-CZ 4.5Å; I224-F235 HydrophobicContact CG2-CD1 3.95Å; I224-F235 HydrophobicContact CG2-CD2 4.06Å; I224-F235 HydrophobicContact CG2-CE1 3.77Å; I224-F235 HydrophobicContact CG2-CE2 3.86Å; I224-F235 HydrophobicContact CG2-CG 4.08Å; I224-F235 HydrophobicContact CG2-CZ 3.7Å; F228-F235 HydrophobicContact CB-CB 4.43Å; F228-F235 HydrophobicContact CD2-CB 3.84Å; F228-F235 HydrophobicContact CE2-CB 4.49Å; F228-F235 HydrophobicContact CG-CB 4.34Å; F235-V238 HydrophobicContact CB-CG2 4.12Å; F235-V238 HydrophobicContact CD1-CG2 3.77Å; F235-V238 HydrophobicContact CG-CG2 4.44Å; F235-L241 HydrophobicContact CE1-CD1 3.61Å; F235-L241 HydrophobicContact CE1-CG 4.44Å; F235-L241 HydrophobicContact CZ-CD1 4.1Å
236	N	93.2	Very high	96.3	Very high	33 Å²	33	41.4 Å²	41.4	18%	0.176	19%	0.194	C	C	.	.	T	Hydrogen-bonded Turn	trans	-75.3	-30.1	-171.7	-66.7	-46.5	0	0	0	113.6	D189 V238	D189-N236 PolarHBondContact O-ND2 3.34Å; D189-N236 PolarHBondContact OD1-N 3.45Å; N236-V238 PolarHBondContact O-N 3.07Å
237	G	96.4	Very high	96.3	Very high	0 Å²	0	40.8 Å²	40.8	0%	0	20%	0.195	C	C	.	.	T	Hydrogen-bonded Turn	trans	-93.2	22.7	-170.8	0	0	0	0	0	116.6	F188 E240 L241	F188-G237 VanDerWaalsContact O-CA 3.22Å; F188-G237 WeakPolarHBondContact O-CA 3.04Å; F188-G237 PolarHBondContact O-N 3.41Å; F188-G237 VanDerWaalsContact O-N 3.13Å; G237-E240 VanDerWaalsContact CA-OE2 3.3Å; G237-E240 WeakPolarHBondContact CA-OE2 3.34Å; G237-L241 VanDerWaalsContact O-CG 3.31Å; G237-L241 WeakPolarHBondContact O-CG 3.4Å; G237-L241 PolarHBondContact O-N 2.98Å; G237-L241 VanDerWaalsContact O-N 3.11Å
238	V	98	Very high	96.3	Very high	2 Å²	2	35.8 Å²	35.8	1%	0.012	18%	0.177	C	C	.	.	H	α-helix	trans	-62.8	-44.1	-176.9	179.2	0	0	0	0	111.2	F225 F228 F235 N236 L241 L242 F280	F225-V238 HydrophobicContact CE1-CG1 4.11Å; F228-V238 HydrophobicContact CD1-CG2 3.97Å; F228-V238 HydrophobicContact CD2-CG2 4.34Å; F228-V238 HydrophobicContact CE1-CG1 4.44Å; F228-V238 HydrophobicContact CE1-CG2 3.85Å; F228-V238 HydrophobicContact CE2-CG2 4.24Å; F228-V238 HydrophobicContact CG-CG2 4.22Å; F228-V238 HydrophobicContact CZ-CG2 4Å; F235-V238 HydrophobicContact CB-CG2 4.12Å; F235-V238 HydrophobicContact CD1-CG2 3.77Å; F235-V238 HydrophobicContact CG-CG2 4.44Å; N236-V238 PolarHBondContact O-N 3.07Å; V238-L241 PolarHBondContact O-N 3.01Å; V238-L242 HydrophobicContact CG1-CD1 3.87Å; V238-L242 HydrophobicContact CG1-CG 4.39Å; V238-L242 WeakPolarHBondContact O-CB 3.49Å; V238-L242 WeakPolarHBondContact O-CG 3.43Å; V238-L242 PolarHBondContact O-N 2.95Å; V238-F280 HydrophobicContact CB-CD1 3.94Å; V238-F280 HydrophobicContact CB-CE1 4.38Å; V238-F280 HydrophobicContact CB-CG 4.16Å; V238-F280 HydrophobicContact CG1-CB 4.19Å; V238-F280 HydrophobicContact CG1-CD1 3.74Å; V238-F280 HydrophobicContact CG1-CD2 3.78Å; V238-F280 HydrophobicContact CG1-CE1 4.03Å; V238-F280 HydrophobicContact CG1-CE2 4.06Å; V238-F280 HydrophobicContact CG1-CG 3.62Å; V238-F280 HydrophobicContact CG1-CZ 4.18Å
239	A	97.9	Very high	96.4	Very high	15 Å²	15	35.6 Å²	35.6	12%	0.124	18%	0.176	C	C	.	.	H	α-helix	trans	-60	-49.2	-179.3	0	0	0	0	0	111.5	L241 L242 E243 F280 Q283	A239-L241 PolarHBondContact O-N 3.39Å; A239-L242 PolarHBondContact O-N 3.46Å; A239-L242 VanDerWaalsContact O-N 3.16Å; A239-E243 PolarHBondContact O-N 2.91Å; A239-F280 HydrophobicContact CB-CB 3.77Å; A239-Q283 HydrophobicContact CB-CG 4.48Å
240	E	98.5	Very high	96.3	Very high	20 Å²	20	38.6 Å²	38.6	9%	0.093	19%	0.192	C	C	.	.	H	α-helix	trans	-66.3	-38.5	-177.8	-64.6	84.2	169.4	0	0	111.6	F188 R196 K200 G237 L242 E243 I244	F188-E240 HydrophobicContact CD1-CB 4.23Å; F188-E240 HydrophobicContact CE1-CB 4.02Å; R196-E240 HydrophobicContact CB-CG 3.97Å; R196-E240 IonicContact CZ-OE1 3.82Å; R196-E240 IonicContact NE-OE1 3.76Å; R196-E240 PolarHBondContact NE-OE1 2.94Å; R196-E240 IonicContact NE-OE2 3.27Å; R196-E240 IonicContact NH2-OE1 3.87Å; R196-E240 PolarHBondContact NH2-OE1 3.03Å; K200-E240 HydrophobicContact CB-CB 4.16Å; K200-E240 HydrophobicContact CD-CB 4.14Å; K200-E240 HydrophobicContact CD-CG 4.37Å; K200-E240 HydrophobicContact CG-CB 4.3Å; G237-E240 VanDerWaalsContact CA-OE2 3.3Å; G237-E240 WeakPolarHBondContact CA-OE2 3.34Å; E240-L242 VanDerWaalsContact C-N 3.34Å; E240-E243 PolarHBondContact O-N 2.87Å; E240-I244 WeakPolarHBondContact O-CG1 3.41Å; E240-I244 PolarHBondContact O-N 3.46Å
241	L	98.7	Very high	96.3	Very high	0 Å²	0	34.7 Å²	34.7	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-65.1	-38.2	173.5	-70.6	-178	0	0	0	112	L185 F188 L203 I221 I224 F225 F235 G237 V238 A239 I244 L245	L185-L241 HydrophobicContact CD2-CD2 4.13Å; F188-L241 HydrophobicContact CD1-CD2 3.7Å; F188-L241 HydrophobicContact CD1-CG 3.9Å; F188-L241 HydrophobicContact CD2-CD2 4.28Å; F188-L241 HydrophobicContact CE1-CD2 3.66Å; F188-L241 HydrophobicContact CE1-CG 4.22Å; F188-L241 HydrophobicContact CE2-CD2 4.23Å; F188-L241 HydrophobicContact CG-CD2 4.01Å; F188-L241 HydrophobicContact CG-CG 4.35Å; F188-L241 HydrophobicContact CZ-CD2 3.93Å; L203-L241 HydrophobicContact CD2-CD2 3.98Å; I221-L241 HydrophobicContact CD1-CD2 4.21Å; I221-L241 HydrophobicContact CG1-CD2 4.21Å; I221-L241 HydrophobicContact CG2-CD1 4.4Å; I224-L241 HydrophobicContact CD1-CD1 4.44Å; I224-L241 HydrophobicContact CG2-CD1 4.2Å; F225-L241 HydrophobicContact CE1-CB 3.98Å; F225-L241 HydrophobicContact CE1-CD1 3.99Å; F225-L241 HydrophobicContact CZ-CB 3.82Å; F235-L241 HydrophobicContact CE1-CD1 3.61Å; F235-L241 HydrophobicContact CE1-CG 4.44Å; F235-L241 HydrophobicContact CZ-CD1 4.1Å; G237-L241 VanDerWaalsContact O-CG 3.31Å; G237-L241 WeakPolarHBondContact O-CG 3.4Å; G237-L241 PolarHBondContact O-N 2.98Å; G237-L241 VanDerWaalsContact O-N 3.11Å; V238-L241 PolarHBondContact O-N 3.01Å; A239-L241 PolarHBondContact O-N 3.39Å; L241-I244 HydrophobicContact CD2-CD1 4.39Å; L241-I244 PolarHBondContact O-N 3.17Å; L241-L245 WeakPolarHBondContact O-CG 3.39Å; L241-L245 PolarHBondContact O-N 2.96Å
242	L	98.7	Very high	96.3	Very high	0 Å²	0	28.7 Å²	28.7	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-67.3	-37.6	175.3	-74.3	170.4	0	0	0	112.3	F225 V238 A239 E240 I244 L245 G246 L268 L271 F280 Q283 L284 C287	F225-L242 HydrophobicContact CE2-CD2 3.93Å; F225-L242 HydrophobicContact CE2-CG 4.45Å; F225-L242 HydrophobicContact CZ-CD2 3.94Å; F225-L242 HydrophobicContact CZ-CG 3.96Å; V238-L242 HydrophobicContact CG1-CD1 3.87Å; V238-L242 HydrophobicContact CG1-CG 4.39Å; V238-L242 WeakPolarHBondContact O-CB 3.49Å; V238-L242 WeakPolarHBondContact O-CG 3.43Å; V238-L242 PolarHBondContact O-N 2.95Å; A239-L242 PolarHBondContact O-N 3.46Å; A239-L242 VanDerWaalsContact O-N 3.16Å; E240-L242 VanDerWaalsContact C-N 3.34Å; L242-I244 VanDerWaalsContact C-N 3.32Å; L242-I244 PolarHBondContact O-N 3.44Å; L242-L245 HydrophobicContact CD2-CD1 4.28Å; L242-L245 CarbonylContact O-C 3.59Å; L242-L245 PolarHBondContact O-N 3.46Å; L242-G246 PolarHBondContact O-N 3.36Å; L242-L268 HydrophobicContact CD2-CD2 3.87Å; L242-L271 HydrophobicContact CD2-CD1 4.23Å; L242-F280 HydrophobicContact CD1-CB 4.15Å; L242-F280 HydrophobicContact CD1-CD2 3.62Å; L242-F280 HydrophobicContact CD1-CE2 4.46Å; L242-F280 HydrophobicContact CD1-CG 4.21Å; L242-Q283 HydrophobicContact CB-CB 3.69Å; L242-Q283 HydrophobicContact CD1-CB 4.4Å; L242-L284 HydrophobicContact CD1-CB 3.9Å; L242-L284 HydrophobicContact CD1-CD1 4.35Å; L242-L284 HydrophobicContact CD2-CD1 4.07Å; L242-C287 PolarHBondContact O-SG 3.19Å
243	E	98.3	Very high	96.4	Very high	79 Å²	79	29.2 Å²	29.2	37%	0.369	18%	0.18	S	C	.	.	H	α-helix	trans	-58.3	-44.6	173.2	-74.3	-175.7	-116.5	0	0	112	K200 A239 E240 L245 G246 S247 Q283	K200-E243 HydrophobicContact CD-CB 3.94Å; K200-E243 HydrophobicContact CD-CG 4.44Å; K200-E243 VanDerWaalsContact NZ-CD 3.31Å; K200-E243 IonicContact NZ-OE1 3.37Å; K200-E243 PolarHBondContact NZ-OE1 3.03Å; K200-E243 VanDerWaalsContact NZ-OE1 3.17Å; K200-E243 IonicContact NZ-OE2 2.9Å; K200-E243 PolarHBondContact NZ-OE2 3.47Å; A239-E243 PolarHBondContact O-N 2.91Å; E240-E243 PolarHBondContact O-N 2.87Å; E243-L245 VanDerWaalsContact C-N 3.34Å; E243-G246 PolarHBondContact O-N 3.33Å; E243-S247 PolarHBondContact O-N 3Å; E243-Q283 HydrophobicContact CG-CG 3.68Å
244	I	98.4	Very high	96.6	Very high	4 Å²	4	31 Å²	31	2%	0.021	19%	0.191	C	C	.	.	H	α-helix	trans	-62.5	-45.8	176.2	-58.6	166.6	0	0	0	109.8	F188 K200 L203 H204 E240 L241 L242 G246 S247 I248	F188-I244 HydrophobicContact CE1-CD1 4.18Å; F188-I244 HydrophobicContact CZ-CD1 3.95Å; K200-I244 HydrophobicContact CB-CD1 4.47Å; K200-I244 HydrophobicContact CG-CD1 4.08Å; K200-I244 HydrophobicContact CG-CG1 3.72Å; L203-I244 HydrophobicContact CB-CD1 4.09Å; L203-I244 HydrophobicContact CD2-CD1 3.74Å; L203-I244 HydrophobicContact CG-CD1 4.14Å; H204-I244 HydrophobicContact CB-CG1 4.42Å; H204-I244 HydrophobicContact CB-CG2 4.32Å; E240-I244 WeakPolarHBondContact O-CG1 3.41Å; E240-I244 PolarHBondContact O-N 3.46Å; L241-I244 HydrophobicContact CD2-CD1 4.39Å; L241-I244 PolarHBondContact O-N 3.17Å; L242-I244 VanDerWaalsContact C-N 3.32Å; L242-I244 PolarHBondContact O-N 3.44Å; I244-G246 VanDerWaalsContact C-N 3.32Å; I244-G246 PolarHBondContact O-N 2.93Å; I244-S247 WeakPolarHBondContact O-CB 3.11Å; I244-S247 PolarHBondContact O-N 3.26Å; I244-I248 HydrophobicContact CG2-CD1 3.74Å; I244-I248 HydrophobicContact CG2-CG1 4.32Å; I244-I248 VanDerWaalsContact O-CG1 3.27Å; I244-I248 WeakPolarHBondContact O-CG1 3.33Å; I244-I248 PolarHBondContact O-N 3.01Å
245	L	98.3	Very high	96.9	Very high	4 Å²	4	33.9 Å²	33.9	2%	0.021	22%	0.215	C	C	.	.	H	α-helix	trans	-62.2	-39.3	179	-76.1	168	0	0	0	112.2	I221 F225 L241 L242 E243 S247 I248 I249 F263	I221-L245 HydrophobicContact CG2-CD1 3.75Å; I221-L245 HydrophobicContact CG2-CG 4.4Å; F225-L245 HydrophobicContact CD2-CD1 4.42Å; F225-L245 HydrophobicContact CE2-CD1 3.34Å; F225-L245 HydrophobicContact CZ-CD1 3.82Å; L241-L245 WeakPolarHBondContact O-CG 3.39Å; L241-L245 PolarHBondContact O-N 2.96Å; L242-L245 HydrophobicContact CD2-CD1 4.28Å; L242-L245 CarbonylContact O-C 3.59Å; L242-L245 PolarHBondContact O-N 3.46Å; E243-L245 VanDerWaalsContact C-N 3.34Å; L245-S247 VanDerWaalsContact C-N 3.33Å; L245-S247 PolarHBondContact O-N 3.15Å; L245-I248 CarbonylContact O-C 3.57Å; L245-I248 WeakPolarHBondContact O-CA 3.38Å; L245-I248 WeakPolarHBondContact O-CB 3.45Å; L245-I248 PolarHBondContact O-N 3.47Å; L245-I248 VanDerWaalsContact O-N 3.07Å; L245-I249 HydrophobicContact CB-CD1 4.38Å; L245-I249 WeakPolarHBondContact O-CB 3.35Å; L245-I249 WeakPolarHBondContact O-CD1 3.26Å; L245-I249 WeakPolarHBondContact O-CG1 3.43Å; L245-I249 PolarHBondContact O-N 3.31Å; L245-F263 HydrophobicContact CD1-CE1 4.44Å; L245-F263 HydrophobicContact CD1-CZ 3.75Å; L245-F263 HydrophobicContact CD2-CE1 4.35Å; L245-F263 HydrophobicContact CD2-CZ 4.17Å
246	G	97.7	Very high	97	Very high	0 Å²	0	33.8 Å²	33.8	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-57	-45.9	175.1	0	0	0	0	0	112	L242 E243 I244 I249 N250	L242-G246 PolarHBondContact O-N 3.36Å; E243-G246 PolarHBondContact O-N 3.33Å; I244-G246 VanDerWaalsContact C-N 3.32Å; I244-G246 PolarHBondContact O-N 2.93Å; G246-I249 PolarHBondContact O-N 3.36Å; G246-N250 PolarHBondContact O-N 3.05Å; G246-N250 VanDerWaalsContact O-N 3.12Å
247	S	96.7	Very high	97.1	Very high	50 Å²	50	38 Å²	38	35%	0.35	23%	0.232	S	C	.	.	H	α-helix	trans	-61.1	-43.5	172.2	177.9	0	0	0	0	112.2	H204 E243 I244 L245 N250 G251	H204-S247 PolarHBondContact CE1-OG 3.17Å; H204-S247 PolarHBondContact NE2-OG 3.02Å; E243-S247 PolarHBondContact O-N 3Å; I244-S247 WeakPolarHBondContact O-CB 3.11Å; I244-S247 PolarHBondContact O-N 3.26Å; L245-S247 VanDerWaalsContact C-N 3.33Å; L245-S247 PolarHBondContact O-N 3.15Å; S247-N250 PolarHBondContact O-N 3.29Å; S247-G251 PolarHBondContact O-N 3.1Å; S247-G251 VanDerWaalsContact O-N 3.16Å
248	I	97.5	Very high	97.1	Very high	9 Å²	9	41.4 Å²	41.4	5%	0.046	26%	0.26	C	S	.	.	H	α-helix	trans	-63.6	-43.5	179.3	-70.1	173	0	0	0	112.1	Y207 I244 L245 G251 F252	Y207-I248 HydrophobicContact CD1-CD1 3.72Å; Y207-I248 HydrophobicContact CD1-CG1 3.69Å; Y207-I248 HydrophobicContact CD2-CD1 3.74Å; Y207-I248 HydrophobicContact CE1-CB 4.26Å; Y207-I248 HydrophobicContact CE1-CD1 3.66Å; Y207-I248 HydrophobicContact CE1-CG1 3.44Å; Y207-I248 VanDerWaalsContact CE1-CG1 3.44Å; Y207-I248 HydrophobicContact CE1-CG2 3.97Å; Y207-I248 HydrophobicContact CE2-CD1 3.66Å; Y207-I248 HydrophobicContact CE2-CG1 4.37Å; Y207-I248 HydrophobicContact CG-CD1 3.77Å; Y207-I248 HydrophobicContact CG-CG1 4.26Å; Y207-I248 VanDerWaalsContact OH-CG2 3.27Å; Y207-I248 WeakPolarHBondContact OH-CG2 3.25Å; I244-I248 HydrophobicContact CG2-CD1 3.74Å; I244-I248 HydrophobicContact CG2-CG1 4.32Å; I244-I248 VanDerWaalsContact O-CG1 3.27Å; I244-I248 WeakPolarHBondContact O-CG1 3.33Å; I244-I248 PolarHBondContact O-N 3.01Å; L245-I248 CarbonylContact O-C 3.57Å; L245-I248 WeakPolarHBondContact O-CA 3.38Å; L245-I248 WeakPolarHBondContact O-CB 3.45Å; L245-I248 PolarHBondContact O-N 3.47Å; L245-I248 VanDerWaalsContact O-N 3.07Å; I248-G251 CarbonylContact O-C 3.55Å; I248-G251 WeakPolarHBondContact O-CA 3.3Å; I248-G251 PolarHBondContact O-N 3.3Å; I248-G251 VanDerWaalsContact O-N 3.13Å; I248-F252 HydrophobicContact CG2-CD1 4.31Å; I248-F252 HydrophobicContact CG2-CE1 3.48Å; I248-F252 VanDerWaalsContact CG2-CE1 3.48Å; I248-F252 HydrophobicContact CG2-CZ 3.92Å; I248-F252 VanDerWaalsContact O-CD1 3.31Å; I248-F252 WeakPolarHBondContact O-CD1 3.44Å; I248-F252 PolarHBondContact O-N 3.36Å
249	I	97.8	Very high	97	Very high	0 Å²	0	45.4 Å²	45.4	0%	0	28%	0.279	C	S	.	.	H	α-helix	trans	-65.1	-44.1	-178.8	-67.8	158	0	0	0	109.7	L245 G246 G251 F252 L268 C287 Q290 F291	L245-I249 HydrophobicContact CB-CD1 4.38Å; L245-I249 WeakPolarHBondContact O-CB 3.35Å; L245-I249 WeakPolarHBondContact O-CD1 3.26Å; L245-I249 WeakPolarHBondContact O-CG1 3.43Å; L245-I249 PolarHBondContact O-N 3.31Å; G246-I249 PolarHBondContact O-N 3.36Å; I249-G251 PolarHBondContact O-N 3.38Å; I249-F252 HydrophobicContact CB-CD2 4.32Å; I249-F252 HydrophobicContact CB-CE2 4.18Å; I249-F252 HydrophobicContact CG1-CD2 4.43Å; I249-F252 HydrophobicContact CG1-CE2 3.8Å; I249-F252 HydrophobicContact CG1-CZ 4.21Å; I249-F252 HydrophobicContact CG2-CD2 4.23Å; I249-F252 HydrophobicContact CG2-CE2 4.35Å; I249-F252 WeakPolarHBondContact O-CB 3.17Å; I249-F252 WeakPolarHBondContact O-CG 3.31Å; I249-F252 PolarHBondContact O-N 3.4Å; I249-L268 HydrophobicContact CD1-CD1 4.34Å; I249-C287 HydrophobicContact CD1-CB 3.85Å; I249-Q290 HydrophobicContact CB-CB 4.48Å; I249-Q290 HydrophobicContact CG2-CB 3.84Å; I249-F291 HydrophobicContact CD1-CD2 3.77Å; I249-F291 HydrophobicContact CD1-CE2 3.43Å; I249-F291 VanDerWaalsContact CD1-CE2 3.43Å; I249-F291 HydrophobicContact CD1-CZ 4.37Å; I249-F291 HydrophobicContact CG1-CD2 4.14Å; I249-F291 HydrophobicContact CG1-CE2 3.62Å; I249-F291 HydrophobicContact CG1-CZ 4.1Å; I249-F291 HydrophobicContact CG2-CD1 4.34Å; I249-F291 HydrophobicContact CG2-CD2 3.79Å; I249-F291 HydrophobicContact CG2-CE2 4.01Å; I249-F291 HydrophobicContact CG2-CG 3.97Å; I249-F291 HydrophobicContact CG2-CZ 4.38Å
250	N	96.1	Very high	97	Very high	76 Å²	76	45.4 Å²	45.4	41%	0.406	28%	0.276	S	S	.	.	H	α-helix	trans	-58.9	-33.6	173.9	-167.9	-1.6	0	0	0	111.6	G246 S247 F252 K294	G246-N250 PolarHBondContact O-N 3.05Å; G246-N250 VanDerWaalsContact O-N 3.12Å; S247-N250 PolarHBondContact O-N 3.29Å; N250-F252 VanDerWaalsContact C-N 3.31Å; N250-F252 PolarHBondContact O-N 2.81Å; N250-K294 WeakPolarHBondContact O-CE 3.5Å; N250-K294 PolarHBondContact O-NZ 3.33Å; N250-K294 PolarHBondContact OD1-NZ 3.32Å; N250-K294 VanDerWaalsContact OD1-NZ 3.13Å
251	G	95.7	Very high	96.9	Very high	66 Å²	66	47.7 Å²	47.7	68%	0.68	29%	0.285	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.9	1	174.8	0	0	0	0	0	116.4	S247 I248 I249	S247-G251 PolarHBondContact O-N 3.1Å; S247-G251 VanDerWaalsContact O-N 3.16Å; I248-G251 CarbonylContact O-C 3.55Å; I248-G251 WeakPolarHBondContact O-CA 3.3Å; I248-G251 PolarHBondContact O-N 3.3Å; I248-G251 VanDerWaalsContact O-N 3.13Å; I249-G251 PolarHBondContact O-N 3.38Å
252	F	96.2	Very high	96.9	Very high	22 Å²	22	53.8 Å²	53.8	10%	0.096	31%	0.314	C	S	.	.	P	Polyproline II helix	trans	-68.2	135.6	-179	-72.9	-20.2	0	0	0	112.8	I248 I249 N250 L256 H260 F291	I248-F252 HydrophobicContact CG2-CD1 4.31Å; I248-F252 HydrophobicContact CG2-CE1 3.48Å; I248-F252 VanDerWaalsContact CG2-CE1 3.48Å; I248-F252 HydrophobicContact CG2-CZ 3.92Å; I248-F252 VanDerWaalsContact O-CD1 3.31Å; I248-F252 WeakPolarHBondContact O-CD1 3.44Å; I248-F252 PolarHBondContact O-N 3.36Å; I249-F252 HydrophobicContact CB-CD2 4.32Å; I249-F252 HydrophobicContact CB-CE2 4.18Å; I249-F252 HydrophobicContact CG1-CD2 4.43Å; I249-F252 HydrophobicContact CG1-CE2 3.8Å; I249-F252 HydrophobicContact CG1-CZ 4.21Å; I249-F252 HydrophobicContact CG2-CD2 4.23Å; I249-F252 HydrophobicContact CG2-CE2 4.35Å; I249-F252 WeakPolarHBondContact O-CB 3.17Å; I249-F252 WeakPolarHBondContact O-CG 3.31Å; I249-F252 PolarHBondContact O-N 3.4Å; N250-F252 VanDerWaalsContact C-N 3.31Å; N250-F252 PolarHBondContact O-N 2.81Å; F252-L256 HydrophobicContact CB-CD2 3.75Å; F252-L256 HydrophobicContact CD2-CD2 3.91Å; F252-L256 HydrophobicContact CG-CD2 4.28Å; F252-H260 AromaticContact CD1-CE1 3.54Å; F252-H260 AromaticContact CD1-ND1 3.84Å; F252-H260 HydrophobicContact CD2-CB 4.3Å; F252-H260 AromaticContact CD2-ND1 3.52Å; F252-H260 AromaticContact CE1-CE1 3.45Å; F252-H260 VanDerWaalsContact CE1-CE1 3.45Å; F252-H260 WeakPolarHBondContact CE1-CE1 3.34Å; F252-H260 AromaticContact CE1-ND1 3.85Å; F252-H260 AromaticContact CE1-NE2 3.69Å; F252-H260 HydrophobicContact CE2-CB 3.86Å; F252-H260 AromaticContact CE2-CG 3.61Å; F252-H260 AromaticContact CE2-ND1 3.55Å; F252-H260 AromaticContact CG-CE1 3.86Å; F252-H260 AromaticContact CG-ND1 3.68Å; F252-H260 HydrophobicContact CZ-CB 4.41Å; F252-H260 AromaticContact CZ-CD2 3.76Å; F252-H260 AromaticContact CZ-CE1 3.71Å; F252-H260 AromaticContact CZ-CG 3.76Å; F252-H260 AromaticContact CZ-ND1 3.71Å; F252-H260 AromaticContact CZ-NE2 3.77Å; F252-F291 HydrophobicContact CD2-CE1 4.33Å; F252-F291 HydrophobicContact CD2-CZ 4.48Å; F252-F291 HydrophobicContact CE2-CE1 4.05Å; F252-F291 AromaticContact CE2-CZ 3.79Å; F252-F291 HydrophobicContact CE2-CZ 3.79Å
253	A	95.2	Very high	96.8	Very high	81 Å²	81	54.5 Å²	54.5	67%	0.669	32%	0.317	S	S	*	.	P	Polyproline II helix	trans	-73.4	146.4	171.5	0	0	0	0	0	110.9	P255	A253-P255 CarbonylContact O-C 3.34Å
254	L	94.8	Very high	96.8	Very high	113 Å²	113	50.8 Å²	50.8	59%	0.592	30%	0.3	S	S	*	.	S	Bend	trans	-96.2	143.1	172.6	-58.8	-178.7	0	0	0	110.2	L256 K294	L254-L256 HydrophobicContact CD2-CD2 4.21Å; L254-L256 HydrophobicContact CD2-CG 4.08Å; L254-K294 HydrophobicContact CD2-CB 4.02Å; L254-K294 HydrophobicContact CD2-CD 4.35Å; L254-K294 VanDerWaalsContact CD2-O 3.26Å; L254-K294 WeakPolarHBondContact CD2-O 3.39Å
255	P	95.8	Very high	96.8	Very high	122 Å²	122	53.3 Å²	53.3	79%	0.792	32%	0.315	S	S	*	.	S	Bend	cis	-70.7	148.6	-3.4	30.5	-35.8	0	0	0	112.8	A253 K257	A253-P255 CarbonylContact O-C 3.34Å; P255-K257 PolarHBondContact O-N 3.4Å
256	L	96.6	Very high	96.7	Very high	14 Å²	14	59.8 Å²	59.8	7%	0.073	34%	0.343	C	S	.	.	P	Polyproline II helix	trans	-60.1	132.6	177.7	-70.7	-179.3	0	0	0	111.4	F252 L254 K261 F291 K294 D295 L298	F252-L256 HydrophobicContact CB-CD2 3.75Å; F252-L256 HydrophobicContact CD2-CD2 3.91Å; F252-L256 HydrophobicContact CG-CD2 4.28Å; L254-L256 HydrophobicContact CD2-CD2 4.21Å; L254-L256 HydrophobicContact CD2-CG 4.08Å; L256-K261 HydrophobicContact CB-CG 4.43Å; L256-F291 HydrophobicContact CD1-CD1 4.1Å; L256-F291 HydrophobicContact CD1-CE1 4.4Å; L256-K294 HydrophobicContact CD1-CB 4.05Å; L256-K294 HydrophobicContact CD2-CB 4.16Å; L256-K294 HydrophobicContact CG-CB 4.3Å; L256-D295 HydrophobicContact CD1-CB 3.56Å; L256-D295 HydrophobicContact CG-CB 4.28Å; L256-L298 HydrophobicContact CD1-CD1 3.78Å
257	K	96.3	Very high	96.7	Very high	122 Å²	122	60.2 Å²	60.2	53%	0.53	35%	0.346	S	S	.	.	P	Polyproline II helix	trans	-65.8	148.6	175.2	-62.9	-175.7	179.3	-175.6	0	111.5	P255 E259 H260 K261	P255-K257 PolarHBondContact O-N 3.4Å; K257-E259 HydrophobicContact CB-CG 3.81Å; K257-E259 HydrophobicContact CD-CG 4.33Å; K257-E259 WeakPolarHBondContact CD-OE1 3.45Å; K257-E259 IonicContact NZ-OE1 3.24Å; K257-E259 PolarHBondContact O-N 2.92Å; K257-H260 WeakPolarHBondContact O-CB 3.42Å; K257-H260 PolarHBondContact O-N 2.99Å; K257-K261 PolarHBondContact O-N 3.15Å
258	A	96.4	Very high	96.8	Very high	70 Å²	70	57.9 Å²	57.9	58%	0.579	33%	0.329	S	S	*	.	H	α-helix	trans	-56.3	-37.4	177.1	0	0	0	0	0	113	H260 K261 Q262	A258-H260 VanDerWaalsContact C-N 3.28Å; A258-H260 PolarHBondContact O-N 2.87Å; A258-K261 PolarHBondContact O-N 3.23Å; A258-Q262 WeakPolarHBondContact O-CG 3.29Å; A258-Q262 PolarHBondContact O-N 3.26Å
259	E	95.8	Very high	96.9	Very high	87 Å²	87	57.7 Å²	57.7	41%	0.407	33%	0.328	S	S	.	.	H	α-helix	trans	-58.8	-37	175.7	54.3	169.4	176.2	0	0	112.7	R218 K257 F263	R218-E259 IonicContact NH2-OE1 3.3Å; R218-E259 PolarHBondContact NH2-OE1 2.88Å; K257-E259 HydrophobicContact CB-CG 3.81Å; K257-E259 HydrophobicContact CD-CG 4.33Å; K257-E259 WeakPolarHBondContact CD-OE1 3.45Å; K257-E259 IonicContact NZ-OE1 3.24Å; K257-E259 PolarHBondContact O-N 2.92Å; E259-F263 WeakPolarHBondContact O-CB 3.49Å; E259-F263 PolarHBondContact O-N 3.45Å
260	H	97.1	Very high	96.9	Very high	14 Å²	14	58 Å²	58	7%	0.065	33%	0.331	C	S	.	.	H	α-helix	trans	-73.8	-39	179.7	-55.7	165.2	0	0	0	111.2	F252 K257 A258 Q262 F263 L264 F291	F252-H260 AromaticContact CD1-CE1 3.54Å; F252-H260 AromaticContact CD1-ND1 3.84Å; F252-H260 HydrophobicContact CD2-CB 4.3Å; F252-H260 AromaticContact CD2-ND1 3.52Å; F252-H260 AromaticContact CE1-CE1 3.45Å; F252-H260 VanDerWaalsContact CE1-CE1 3.45Å; F252-H260 WeakPolarHBondContact CE1-CE1 3.34Å; F252-H260 AromaticContact CE1-ND1 3.85Å; F252-H260 AromaticContact CE1-NE2 3.69Å; F252-H260 HydrophobicContact CE2-CB 3.86Å; F252-H260 AromaticContact CE2-CG 3.61Å; F252-H260 AromaticContact CE2-ND1 3.55Å; F252-H260 AromaticContact CG-CE1 3.86Å; F252-H260 AromaticContact CG-ND1 3.68Å; F252-H260 HydrophobicContact CZ-CB 4.41Å; F252-H260 AromaticContact CZ-CD2 3.76Å; F252-H260 AromaticContact CZ-CE1 3.71Å; F252-H260 AromaticContact CZ-CG 3.76Å; F252-H260 AromaticContact CZ-ND1 3.71Å; F252-H260 AromaticContact CZ-NE2 3.77Å; K257-H260 WeakPolarHBondContact O-CB 3.42Å; K257-H260 PolarHBondContact O-N 2.99Å; A258-H260 VanDerWaalsContact C-N 3.28Å; A258-H260 PolarHBondContact O-N 2.87Å; H260-Q262 VanDerWaalsContact C-N 3.33Å; H260-Q262 PolarHBondContact O-N 2.91Å; H260-F263 WeakPolarHBondContact O-CB 3.22Å; H260-F263 PolarHBondContact O-N 3.01Å; H260-L264 PolarHBondContact O-N 2.45Å; H260-F291 HydrophobicContact CB-CE1 4.02Å; H260-F291 HydrophobicContact CB-CZ 4.26Å; H260-F291 WeakPolarHBondContact O-CZ 3.35Å
261	K	97.5	Very high	97	Very high	68 Å²	68	54.4 Å²	54.4	30%	0.296	31%	0.311	S	S	.	.	H	α-helix	trans	-63.2	-40.6	174	-61.6	-172.7	174.4	-156.5	0	111.5	L256 K257 A258 L264 V265 D295 L298	L256-K261 HydrophobicContact CB-CG 4.43Å; K257-K261 PolarHBondContact O-N 3.15Å; A258-K261 PolarHBondContact O-N 3.23Å; K261-L264 PolarHBondContact O-N 3Å; K261-V265 PolarHBondContact O-N 3.07Å; K261-D295 WeakPolarHBondContact CE-OD2 3.29Å; K261-D295 IonicContact NZ-OD2 3.59Å; K261-D295 PolarHBondContact NZ-OD2 3.42Å; K261-L298 HydrophobicContact CB-CD2 4.47Å; K261-L298 HydrophobicContact CD-CD2 4.03Å; K261-L298 HydrophobicContact CG-CD1 4.32Å; K261-L298 HydrophobicContact CG-CD2 4.1Å
262	Q	97	Very high	97.1	Very high	129 Å²	129	51.3 Å²	51.3	60%	0.603	28%	0.279	S	S	*	.	H	α-helix	trans	-65	-41.9	174	-73.2	179.6	-0.3	0	0	111.7	A258 H260 L264 V265 K266	A258-Q262 WeakPolarHBondContact O-CG 3.29Å; A258-Q262 PolarHBondContact O-N 3.26Å; H260-Q262 VanDerWaalsContact C-N 3.33Å; H260-Q262 PolarHBondContact O-N 2.91Å; Q262-L264 PolarHBondContact O-N 3.36Å; Q262-V265 PolarHBondContact O-N 3.11Å; Q262-K266 WeakPolarHBondContact O-CB 3.37Å; Q262-K266 WeakPolarHBondContact O-CG 3.46Å; Q262-K266 PolarHBondContact O-N 3.44Å
263	F	97.7	Very high	97.1	Very high	15 Å²	15	53 Å²	53	7%	0.066	29%	0.291	C	S	.	.	H	α-helix	trans	-57.1	-47.1	175.6	171.5	-112.6	0	0	0	112.2	N222 F225 L245 E259 H260 V265 V267 L268 F291	N222-F263 WeakPolarHBondContact OD1-CD2 3.31Å; N222-F263 WeakPolarHBondContact OD1-CE2 3.31Å; F225-F263 HydrophobicContact CD2-CE2 4.41Å; L245-F263 HydrophobicContact CD1-CE1 4.44Å; L245-F263 HydrophobicContact CD1-CZ 3.75Å; L245-F263 HydrophobicContact CD2-CE1 4.35Å; L245-F263 HydrophobicContact CD2-CZ 4.17Å; E259-F263 WeakPolarHBondContact O-CB 3.49Å; E259-F263 PolarHBondContact O-N 3.45Å; H260-F263 WeakPolarHBondContact O-CB 3.22Å; H260-F263 PolarHBondContact O-N 3.01Å; F263-V265 PolarHBondContact O-N 3.23Å; F263-V267 HydrophobicContact CD2-CB 3.67Å; F263-V267 HydrophobicContact CD2-CG1 4.16Å; F263-V267 HydrophobicContact CD2-CG2 3.79Å; F263-V267 HydrophobicContact CE2-CB 3.74Å; F263-V267 HydrophobicContact CE2-CG1 3.74Å; F263-V267 HydrophobicContact CE2-CG2 4.24Å; F263-V267 WeakPolarHBondContact O-CA 3.32Å; F263-V267 VanDerWaalsContact O-CB 3.3Å; F263-V267 WeakPolarHBondContact O-CB 3.39Å; F263-V267 PolarHBondContact O-N 3.21Å; F263-L268 HydrophobicContact CD1-CD1 4.22Å; F263-L268 HydrophobicContact CD1-CG 4.21Å; F263-L268 HydrophobicContact CE1-CD1 3.72Å; F263-L268 HydrophobicContact CE1-CD2 3.82Å; F263-L268 HydrophobicContact CE1-CG 3.66Å; F263-L268 HydrophobicContact CE2-CD2 4.31Å; F263-L268 HydrophobicContact CE2-CG 4.45Å; F263-L268 HydrophobicContact CZ-CD1 4.32Å; F263-L268 HydrophobicContact CZ-CD2 3.54Å; F263-L268 HydrophobicContact CZ-CG 3.8Å; F263-L268 PolarHBondContact O-N 2.99Å; F263-L268 VanDerWaalsContact O-N 3.15Å; F263-F291 HydrophobicContact CD1-CE2 4.03Å; F263-F291 HydrophobicContact CD1-CZ 4.01Å; F263-F291 HydrophobicContact CE1-CE2 4.28Å
264	L	98.2	Very high	97.1	Very high	0 Å²	0	49.1 Å²	49.1	0%	0	26%	0.259	C	S	.	.	I	π-helix	trans	-53.7	-55.6	174.2	173.6	63.1	0	0	0	111.5	H260 K261 Q262 L268 I269 I288 F291 L298 V302	H260-L264 PolarHBondContact O-N 2.45Å; K261-L264 PolarHBondContact O-N 3Å; Q262-L264 PolarHBondContact O-N 3.36Å; L264-L268 HydrophobicContact CD1-CB 4.3Å; L264-L268 HydrophobicContact CD1-CD1 4.12Å; L264-L268 PolarHBondContact O-N 2.91Å; L264-I269 WeakPolarHBondContact O-CG1 3.45Å; L264-I269 PolarHBondContact O-N 3.47Å; L264-I288 HydrophobicContact CD1-CD1 3.43Å; L264-I288 VanDerWaalsContact CD1-CD1 3.43Å; L264-F291 HydrophobicContact CB-CD1 4.4Å; L264-F291 HydrophobicContact CB-CD2 4.29Å; L264-F291 HydrophobicContact CB-CE1 4.33Å; L264-F291 HydrophobicContact CB-CE2 4.21Å; L264-F291 HydrophobicContact CB-CG 4.38Å; L264-F291 HydrophobicContact CB-CZ 4.22Å; L264-F291 HydrophobicContact CD1-CB 4.21Å; L264-F291 HydrophobicContact CD1-CD2 3.91Å; L264-F291 HydrophobicContact CD1-CG 4.11Å; L264-F291 HydrophobicContact CD2-CB 4.03Å; L264-F291 HydrophobicContact CD2-CD1 4.17Å; L264-F291 HydrophobicContact CD2-CG 4.04Å; L264-F291 HydrophobicContact CG-CD2 4.49Å; L264-F291 HydrophobicContact CG-CG 4.41Å; L264-L298 HydrophobicContact CD2-CB 4.02Å; L264-L298 HydrophobicContact CD2-CD1 3.82Å; L264-L298 HydrophobicContact CD2-CG 4.37Å; L264-V302 HydrophobicContact CD1-CG2 4.05Å; L264-V302 HydrophobicContact CD2-CG2 3.79Å; L264-V302 HydrophobicContact CG-CG2 4.09Å
265	V	97.6	Very high	97	Very high	57 Å²	57	53.4 Å²	53.4	35%	0.345	27%	0.267	S	S	.	.	I	π-helix	trans	-75.2	-33.9	-171.6	177.4	0	0	0	0	113.3	K261 Q262 F263 I269	K261-V265 PolarHBondContact O-N 3.07Å; Q262-V265 PolarHBondContact O-N 3.11Å; F263-V265 PolarHBondContact O-N 3.23Å; V265-I269 HydrophobicContact CG2-CD1 4.43Å
266	K	97.3	Very high	96.9	Very high	141 Å²	141	48.6 Å²	48.6	61%	0.613	24%	0.237	S	C	*	.	I	π-helix	trans	-99.1	-16.3	-171.9	-60.9	-63.5	-172.9	178	0	114.1	Q262	Q262-K266 WeakPolarHBondContact O-CB 3.37Å; Q262-K266 WeakPolarHBondContact O-CG 3.46Å; Q262-K266 PolarHBondContact O-N 3.44Å
267	V	98	Very high	96.8	Very high	9 Å²	9	48 Å²	48	6%	0.055	23%	0.234	C	C	.	.	I	π-helix	trans	-124.5	-56.8	-177.5	-170.2	0	0	0	0	111.3	F225 L226 F263 P270 L271	F225-V267 HydrophobicContact CB-CG1 3.51Å; F225-V267 HydrophobicContact CD2-CG1 3.74Å; F225-V267 HydrophobicContact CG-CG1 4.15Å; L226-V267 HydrophobicContact CD2-CG2 4.22Å; L226-V267 HydrophobicContact CG-CG2 4.43Å; F263-V267 HydrophobicContact CD2-CB 3.67Å; F263-V267 HydrophobicContact CD2-CG1 4.16Å; F263-V267 HydrophobicContact CD2-CG2 3.79Å; F263-V267 HydrophobicContact CE2-CB 3.74Å; F263-V267 HydrophobicContact CE2-CG1 3.74Å; F263-V267 HydrophobicContact CE2-CG2 4.24Å; F263-V267 WeakPolarHBondContact O-CA 3.32Å; F263-V267 VanDerWaalsContact O-CB 3.3Å; F263-V267 WeakPolarHBondContact O-CB 3.39Å; F263-V267 PolarHBondContact O-N 3.21Å; V267-P270 WeakPolarHBondContact O-CD 3.47Å; V267-L271 WeakPolarHBondContact O-CG 3.29Å; V267-L271 PolarHBondContact O-N 3.37Å
268	L	98.5	Very high	96.8	Very high	0 Å²	0	44 Å²	44	0%	0	22%	0.221	C	C	.	.	I	π-helix	trans	-66.6	-46.9	-176.3	-63.6	-175.3	0	0	0	113	L242 I249 F263 L264 L271 H272 L284 C287 I288 F291	L242-L268 HydrophobicContact CD2-CD2 3.87Å; I249-L268 HydrophobicContact CD1-CD1 4.34Å; F263-L268 HydrophobicContact CD1-CD1 4.22Å; F263-L268 HydrophobicContact CD1-CG 4.21Å; F263-L268 HydrophobicContact CE1-CD1 3.72Å; F263-L268 HydrophobicContact CE1-CD2 3.82Å; F263-L268 HydrophobicContact CE1-CG 3.66Å; F263-L268 HydrophobicContact CE2-CD2 4.31Å; F263-L268 HydrophobicContact CE2-CG 4.45Å; F263-L268 HydrophobicContact CZ-CD1 4.32Å; F263-L268 HydrophobicContact CZ-CD2 3.54Å; F263-L268 HydrophobicContact CZ-CG 3.8Å; F263-L268 PolarHBondContact O-N 2.99Å; F263-L268 VanDerWaalsContact O-N 3.15Å; L264-L268 HydrophobicContact CD1-CB 4.3Å; L264-L268 HydrophobicContact CD1-CD1 4.12Å; L264-L268 PolarHBondContact O-N 2.91Å; L268-L271 HydrophobicContact CD2-CD1 4.12Å; L268-L271 WeakPolarHBondContact O-CB 3.33Å; L268-L271 PolarHBondContact O-N 3.23Å; L268-H272 PolarHBondContact O-CE1 2.91Å; L268-H272 PolarHBondContact O-ND1 2.65Å; L268-L284 HydrophobicContact CB-CD1 4.21Å; L268-L284 HydrophobicContact CD2-CD1 4.01Å; L268-C287 HydrophobicContact CD1-CB 4.1Å; L268-I288 HydrophobicContact CB-CD1 3.84Å; L268-I288 HydrophobicContact CD1-CD1 4.32Å; L268-F291 HydrophobicContact CD1-CD2 3.81Å; L268-F291 HydrophobicContact CD1-CE2 3.59Å
269	I	98.4	Very high	96.7	Very high	5 Å²	5	44.2 Å²	44.2	3%	0.026	21%	0.212	C	C	.	.	H	α-helix	trans	-61.4	-47.8	178.9	-62.5	175.4	0	0	0	111.4	L264 V265 L271 H272 V302 F309	L264-I269 WeakPolarHBondContact O-CG1 3.45Å; L264-I269 PolarHBondContact O-N 3.47Å; V265-I269 HydrophobicContact CG2-CD1 4.43Å; I269-L271 VanDerWaalsContact C-N 3.26Å; I269-L271 PolarHBondContact O-N 3.38Å; I269-H272 PolarHBondContact O-N 3.16Å; I269-H272 PolarHBondContact O-ND1 3.35Å; I269-V302 HydrophobicContact CD1-CG2 4.15Å; I269-F309 HydrophobicContact CG2-CD2 3.88Å; I269-F309 HydrophobicContact CG2-CE2 3.86Å
270	P	98.1	Very high	96.7	Very high	8 Å²	8	40.2 Å²	40.2	5%	0.052	19%	0.194	C	C	.	.	H	α-helix	trans	-60.9	-24.5	175.9	-28.9	38.4	0	0	0	115.8	V229 Y230 V267 H272 T273 F309	V229-P270 HydrophobicContact CG1-CB 4.17Å; Y230-P270 WeakPolarHBondContact OH-CB 3.38Å; V267-P270 WeakPolarHBondContact O-CD 3.47Å; P270-H272 PolarHBondContact O-N 3.46Å; P270-T273 PolarHBondContact O-N 3.2Å; P270-T273 PolarHBondContact O-OG1 2.94Å; P270-F309 HydrophobicContact CG-CE2 4.41Å
271	L	98.3	Very high	96.8	Very high	0 Å²	0	40.6 Å²	40.6	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-57.3	-24.4	176.6	-79.7	167.7	0	0	0	113	F225 F228 V229 L242 V267 L268 I269 T273 V274 F280 L284	F225-L271 HydrophobicContact CB-CD2 4.44Å; F225-L271 HydrophobicContact CD2-CD1 3.91Å; F225-L271 HydrophobicContact CE2-CD1 4.1Å; F225-L271 HydrophobicContact CG-CD1 4.2Å; F225-L271 HydrophobicContact CG-CD2 4.46Å; F228-L271 HydrophobicContact CD1-CD2 3.67Å; F228-L271 HydrophobicContact CE1-CD2 3.88Å; V229-L271 HydrophobicContact CG2-CD2 3.48Å; V229-L271 VanDerWaalsContact CG2-CD2 3.48Å; V229-L271 HydrophobicContact CG2-CG 4.03Å; L242-L271 HydrophobicContact CD2-CD1 4.23Å; V267-L271 WeakPolarHBondContact O-CG 3.29Å; V267-L271 PolarHBondContact O-N 3.37Å; L268-L271 HydrophobicContact CD2-CD1 4.12Å; L268-L271 WeakPolarHBondContact O-CB 3.33Å; L268-L271 PolarHBondContact O-N 3.23Å; I269-L271 VanDerWaalsContact C-N 3.26Å; I269-L271 PolarHBondContact O-N 3.38Å; L271-T273 PolarHBondContact O-N 3.43Å; L271-V274 VanDerWaalsContact O-CG2 3.23Å; L271-V274 WeakPolarHBondContact O-CG2 3.38Å; L271-F280 HydrophobicContact CB-CE2 4.48Å; L271-L284 HydrophobicContact CB-CD1 4.29Å; L271-L284 HydrophobicContact CB-CD2 3.72Å; L271-L284 HydrophobicContact CD1-CD1 4.11Å
272	H	98.3	Very high	96.8	Very high	0 Å²	0	40.6 Å²	40.6	0%	0	21%	0.208	C	C	.	.	T	Hydrogen-bonded Turn	trans	-66.5	-15.9	176.8	-58.9	82.4	0	0	0	113.7	L268 I269 P270 L277 L284 K317 F321 E324	L268-H272 PolarHBondContact O-CE1 2.91Å; L268-H272 PolarHBondContact O-ND1 2.65Å; I269-H272 PolarHBondContact O-N 3.16Å; I269-H272 PolarHBondContact O-ND1 3.35Å; P270-H272 PolarHBondContact O-N 3.46Å; H272-L277 HydrophobicContact CB-CD2 4.49Å; H272-L284 WeakPolarHBondContact CE1-CD2 2.89Å; H272-L284 VanDerWaalsContact NE2-CD2 3.32Å; H272-L284 WeakPolarHBondContact NE2-CD2 2.96Å; H272-K317 WeakPolarHBondContact O-CE 3.29Å; H272-K317 PolarHBondContact O-NZ 2.64Å; H272-F321 HydrophobicContact CB-CE2 4.1Å; H272-F321 HydrophobicContact CB-CZ 3.67Å; H272-E324 IonicContact CD2-OE2 3.74Å; H272-E324 PolarHBondContact CD2-OE2 3.23Å; H272-E324 IonicContact CE1-OE1 3.09Å; H272-E324 IonicContact NE2-OE1 3.81Å; H272-E324 PolarHBondContact NE2-OE1 3.23Å; H272-E324 VanDerWaalsContact NE2-OE1 3.15Å; H272-E324 IonicContact NE2-OE2 2.85Å; H272-E324 PolarHBondContact NE2-OE2 3Å
273	T	96.7	Very high	96.9	Very high	57 Å²	57	36.9 Å²	36.9	35%	0.35	19%	0.191	S	C	.	.	T	Hydrogen-bonded Turn	trans	-78.9	-28.5	-175.7	64.3	0	0	0	0	113.2	P270 L271 F309 K317	P270-T273 PolarHBondContact O-N 3.2Å; P270-T273 PolarHBondContact O-OG1 2.94Å; L271-T273 PolarHBondContact O-N 3.43Å; T273-F309 HydrophobicContact CG2-CB 3.97Å; T273-F309 HydrophobicContact CG2-CD1 3.5Å; T273-F309 VanDerWaalsContact CG2-CD1 3.5Å; T273-F309 HydrophobicContact CG2-CD2 3.91Å; T273-F309 HydrophobicContact CG2-CE1 3.86Å; T273-F309 HydrophobicContact CG2-CE2 4.23Å; T273-F309 HydrophobicContact CG2-CG 3.53Å; T273-F309 HydrophobicContact CG2-CZ 4.21Å; T273-K317 PolarHBondContact O-NZ 3.49Å; T273-K317 VanDerWaalsContact O-NZ 3.08Å
274	V	95	Very high	96.9	Very high	0 Å²	0	36.1 Å²	36.1	0%	0	19%	0.188	C	C	.	.	S	Bend	trans	-64.7	154.8	-174	-56.5	0	0	0	0	112.3	F228 V229 L271 F280 K317	F228-V274 HydrophobicContact CD1-CG1 4.44Å; F228-V274 HydrophobicContact CE1-CB 4.28Å; F228-V274 HydrophobicContact CE1-CG1 3.94Å; F228-V274 HydrophobicContact CE1-CG2 3.82Å; F228-V274 HydrophobicContact CZ-CB 4.26Å; F228-V274 HydrophobicContact CZ-CG1 4.26Å; F228-V274 HydrophobicContact CZ-CG2 3.91Å; V229-V274 HydrophobicContact CB-CG1 4.43Å; V229-V274 HydrophobicContact CG2-CG1 4.11Å; L271-V274 VanDerWaalsContact O-CG2 3.23Å; L271-V274 WeakPolarHBondContact O-CG2 3.38Å; V274-F280 HydrophobicContact CG2-CE1 4.1Å; V274-F280 HydrophobicContact CG2-CZ 3.48Å; V274-F280 VanDerWaalsContact CG2-CZ 3.48Å; V274-K317 PolarHBondContact O-NZ 2.98Å
275	R	92.7	Very high	96.9	Very high	203 Å²	203	36.1 Å²	36.1	77%	0.766	19%	0.188	S	C	*	.	G	3₁₀ helix	trans	-69.2	-43.9	-173.6	-57.4	-179.4	-155.8	-166.8	0.9	112.4	E233 L277	E233-R275 IonicContact OE2-CZ 2.82Å; E233-R275 IonicContact OE2-NE 2.73Å; E233-R275 PolarHBondContact OE2-NE 3.15Å; E233-R275 IonicContact OE2-NH2 3.91Å; R275-L277 PolarHBondContact O-N 2.78Å
276	S	92.9	Very high	97	Very high	22 Å²	22	38.2 Å²	38.2	15%	0.154	19%	0.19	C	C	.	.	G	3₁₀ helix	trans	-77	25.9	-178.3	51.4	0	0	0	0	114.6	S278 L279 F280	S276-S278 PolarHBondContact O-N 3.06Å; S276-L279 PolarHBondContact O-N 3.32Å; S276-F280 WeakPolarHBondContact O-CE1 3.19Å
277	L	95.9	Very high	97	Very high	0 Å²	0	31.5 Å²	31.5	0%	0	16%	0.161	C	C	.	.	G	3₁₀ helix	trans	-56.7	-36	-177.6	178.8	61.3	0	0	0	112.4	H272 R275 L279 F280 H281 L284 M320 F321	H272-L277 HydrophobicContact CB-CD2 4.49Å; R275-L277 PolarHBondContact O-N 2.78Å; L277-L279 PolarHBondContact O-N 3.17Å; L277-L279 VanDerWaalsContact O-N 3.11Å; L277-F280 HydrophobicContact CD1-CD2 4.29Å; L277-F280 HydrophobicContact CD1-CE2 3.62Å; L277-F280 HydrophobicContact CD1-CZ 4.04Å; L277-F280 PolarHBondContact O-N 3.41Å; L277-F280 VanDerWaalsContact O-N 3.15Å; L277-H281 HydrophobicContact CD1-CB 4.3Å; L277-H281 HydrophobicContact CG-CB 4.18Å; L277-H281 WeakPolarHBondContact O-CA 3.45Å; L277-H281 VanDerWaalsContact O-CB 3.29Å; L277-H281 WeakPolarHBondContact O-CB 3.33Å; L277-H281 PolarHBondContact O-N 3.34Å; L277-L284 HydrophobicContact CD1-CD2 3.93Å; L277-M320 HydrophobicContact CB-CE 4.33Å; L277-M320 HydrophobicContact CD2-CE 4.14Å; L277-M320 HydrophobicContact CG-CE 3.78Å; L277-F321 HydrophobicContact CD2-CD2 4.34Å; L277-F321 HydrophobicContact CD2-CE2 3.73Å
278	S	95	Very high	97.1	Very high	39 Å²	39	31 Å²	31	27%	0.273	16%	0.158	S	C	.	.	G	3₁₀ helix	trans	-47.5	-35.3	177.6	45.3	0	0	0	0	114.2	E138 S276 F280 M320	E138-S278 WeakPolarHBondContact OE1-CB 3.2Å; E138-S278 PolarHBondContact OE1-OG 3.41Å; S276-S278 PolarHBondContact O-N 3.06Å; S278-F280 VanDerWaalsContact C-N 3.34Å; S278-F280 PolarHBondContact O-N 3.2Å; S278-M320 VanDerWaalsContact CA-CE 3.45Å
279	L	94.2	Very high	97	Very high	74 Å²	74	31.8 Å²	31.8	39%	0.387	16%	0.162	S	C	.	.	G	3₁₀ helix	trans	-71.3	-26.3	-175.4	-55.6	173.3	0	0	0	113.8	P137 E138 S276 L277	P137-L279 HydrophobicContact CB-CD1 3.39Å; P137-L279 HydrophobicContact CB-CD2 4.2Å; P137-L279 HydrophobicContact CB-CG 4.38Å; P137-L279 HydrophobicContact CG-CD1 3.88Å; E138-L279 HydrophobicContact CG-CD2 3.87Å; S276-L279 PolarHBondContact O-N 3.32Å; L277-L279 PolarHBondContact O-N 3.17Å; L277-L279 VanDerWaalsContact O-N 3.11Å
280	F	97.1	Very high	97	Very high	4 Å²	4	32.2 Å²	32.2	2%	0.018	16%	0.164	C	C	.	.	T	Hydrogen-bonded Turn	trans	-137.4	8	-171.1	60.8	-98.4	0	0	0	113.9	F228 V238 A239 L242 L271 V274 S276 L277 S278 A282 Q283 L284	F228-F280 HydrophobicContact CE1-CE1 4.07Å; F228-F280 AromaticContact CE1-CZ 3.97Å; F228-F280 HydrophobicContact CE1-CZ 3.97Å; F228-F280 AromaticContact CZ-CE1 3.98Å; F228-F280 HydrophobicContact CZ-CE1 3.98Å; F228-F280 HydrophobicContact CZ-CZ 4.29Å; V238-F280 HydrophobicContact CB-CD1 3.94Å; V238-F280 HydrophobicContact CB-CE1 4.38Å; V238-F280 HydrophobicContact CB-CG 4.16Å; V238-F280 HydrophobicContact CG1-CB 4.19Å; V238-F280 HydrophobicContact CG1-CD1 3.74Å; V238-F280 HydrophobicContact CG1-CD2 3.78Å; V238-F280 HydrophobicContact CG1-CE1 4.03Å; V238-F280 HydrophobicContact CG1-CE2 4.06Å; V238-F280 HydrophobicContact CG1-CG 3.62Å; V238-F280 HydrophobicContact CG1-CZ 4.18Å; A239-F280 HydrophobicContact CB-CB 3.77Å; L242-F280 HydrophobicContact CD1-CB 4.15Å; L242-F280 HydrophobicContact CD1-CD2 3.62Å; L242-F280 HydrophobicContact CD1-CE2 4.46Å; L242-F280 HydrophobicContact CD1-CG 4.21Å; L271-F280 HydrophobicContact CB-CE2 4.48Å; V274-F280 HydrophobicContact CG2-CE1 4.1Å; V274-F280 HydrophobicContact CG2-CZ 3.48Å; V274-F280 VanDerWaalsContact CG2-CZ 3.48Å; S276-F280 WeakPolarHBondContact O-CE1 3.19Å; L277-F280 HydrophobicContact CD1-CD2 4.29Å; L277-F280 HydrophobicContact CD1-CE2 3.62Å; L277-F280 HydrophobicContact CD1-CZ 4.04Å; L277-F280 PolarHBondContact O-N 3.41Å; L277-F280 VanDerWaalsContact O-N 3.15Å; S278-F280 VanDerWaalsContact C-N 3.34Å; S278-F280 PolarHBondContact O-N 3.2Å; F280-A282 PolarHBondContact O-N 3.37Å; F280-Q283 VanDerWaalsContact CA-OE1 3.28Å; F280-Q283 PolarHBondContact O-N 2.81Å; F280-Q283 PolarHBondContact O-OE1 3.15Å; F280-L284 HydrophobicContact CD2-CB 4.36Å; F280-L284 HydrophobicContact CD2-CD2 4.47Å; F280-L284 HydrophobicContact CE2-CD2 4.11Å; F280-L284 PolarHBondContact O-N 2.95Å
281	H	98.2	Very high	97	Very high	21 Å²	21	31.8 Å²	31.8	10%	0.097	16%	0.162	C	C	.	.	H	α-helix	trans	-58.5	-43.2	-175.4	177.3	-99.2	0	0	0	113.3	L277 Q283 L284 A285 M320 E324	L277-H281 HydrophobicContact CD1-CB 4.3Å; L277-H281 HydrophobicContact CG-CB 4.18Å; L277-H281 WeakPolarHBondContact O-CA 3.45Å; L277-H281 VanDerWaalsContact O-CB 3.29Å; L277-H281 WeakPolarHBondContact O-CB 3.33Å; L277-H281 PolarHBondContact O-N 3.34Å; H281-Q283 VanDerWaalsContact C-N 3.29Å; H281-Q283 PolarHBondContact O-N 2.96Å; H281-L284 PolarHBondContact O-N 3.41Å; H281-L284 VanDerWaalsContact O-N 3.16Å; H281-A285 WeakPolarHBondContact O-CB 3.26Å; H281-A285 PolarHBondContact O-N 2.92Å; H281-M320 HydrophobicContact CB-CE 3.15Å; H281-M320 PolarHBondContact CE1-O 3.48Å; H281-M320 PolarHBondContact NE2-O 3.21Å; H281-E324 IonicContact NE2-OE2 2.76Å
282	A	98.1	Very high	97	Very high	69 Å²	69	32 Å²	32	57%	0.57	16%	0.163	S	C	*	.	H	α-helix	trans	-60.8	-41.5	-179.4	0	0	0	0	0	111.6	F280 Y286	F280-A282 PolarHBondContact O-N 3.37Å; A282-Y286 WeakPolarHBondContact O-CB 3.45Å; A282-Y286 PolarHBondContact O-N 3.22Å
283	Q	98.5	Very high	96.9	Very high	50 Å²	50	37.1 Å²	37.1	23%	0.234	19%	0.187	C	C	.	.	H	α-helix	trans	-68	-37.5	177.1	-61.5	78.7	-4.1	0	0	111.3	A239 L242 E243 F280 H281 C287	A239-Q283 HydrophobicContact CB-CG 4.48Å; L242-Q283 HydrophobicContact CB-CB 3.69Å; L242-Q283 HydrophobicContact CD1-CB 4.4Å; E243-Q283 HydrophobicContact CG-CG 3.68Å; F280-Q283 VanDerWaalsContact CA-OE1 3.28Å; F280-Q283 PolarHBondContact O-N 2.81Å; F280-Q283 PolarHBondContact O-OE1 3.15Å; H281-Q283 VanDerWaalsContact C-N 3.29Å; H281-Q283 PolarHBondContact O-N 2.96Å; Q283-C287 PolarHBondContact O-N 3.49Å; Q283-C287 VanDerWaalsContact O-N 3.11Å; Q283-C287 PolarHBondContact O-SG 3.41Å
284	L	98.7	Very high	96.9	Very high	0 Å²	0	36.7 Å²	36.7	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-67.1	-50.6	176.2	-176.6	56	0	0	0	111.7	L242 L268 L271 H272 L277 F280 H281 Y286 C287 I288	L242-L284 HydrophobicContact CD1-CB 3.9Å; L242-L284 HydrophobicContact CD1-CD1 4.35Å; L242-L284 HydrophobicContact CD2-CD1 4.07Å; L268-L284 HydrophobicContact CB-CD1 4.21Å; L268-L284 HydrophobicContact CD2-CD1 4.01Å; L271-L284 HydrophobicContact CB-CD1 4.29Å; L271-L284 HydrophobicContact CB-CD2 3.72Å; L271-L284 HydrophobicContact CD1-CD1 4.11Å; H272-L284 WeakPolarHBondContact CE1-CD2 2.89Å; H272-L284 VanDerWaalsContact NE2-CD2 3.32Å; H272-L284 WeakPolarHBondContact NE2-CD2 2.96Å; L277-L284 HydrophobicContact CD1-CD2 3.93Å; F280-L284 HydrophobicContact CD2-CB 4.36Å; F280-L284 HydrophobicContact CD2-CD2 4.47Å; F280-L284 HydrophobicContact CE2-CD2 4.11Å; F280-L284 PolarHBondContact O-N 2.95Å; H281-L284 PolarHBondContact O-N 3.41Å; H281-L284 VanDerWaalsContact O-N 3.16Å; L284-Y286 VanDerWaalsContact C-N 3.3Å; L284-Y286 PolarHBondContact O-N 3.29Å; L284-C287 WeakPolarHBondContact O-CA 3.18Å; L284-C287 WeakPolarHBondContact O-CB 3.45Å; L284-C287 PolarHBondContact O-N 3.47Å; L284-I288 WeakPolarHBondContact O-CG1 3.47Å; L284-I288 PolarHBondContact O-N 2.94Å
285	A	98.5	Very high	97	Very high	0 Å²	0	38.2 Å²	38.2	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-55.6	-45.8	176.3	0	0	0	0	0	110.9	H281 C287 I288 V289 E324	H281-A285 WeakPolarHBondContact O-CB 3.26Å; H281-A285 PolarHBondContact O-N 2.92Å; A285-C287 VanDerWaalsContact C-N 3.33Å; A285-C287 PolarHBondContact O-N 3.39Å; A285-I288 WeakPolarHBondContact O-CB 3.46Å; A285-I288 PolarHBondContact O-N 3.33Å; A285-I288 VanDerWaalsContact O-N 3.07Å; A285-V289 WeakPolarHBondContact O-CG2 3.43Å; A285-V289 PolarHBondContact O-N 2.96Å; A285-E324 HydrophobicContact CB-CB 4.24Å; A285-E324 HydrophobicContact CB-CG 3.82Å
286	Y	98.4	Very high	97.2	Very high	100 Å²	100	30.1 Å²	30.1	39%	0.392	16%	0.162	S	C	.	.	H	α-helix	trans	-56.1	-44.8	173.3	177	-102.8	0	0	0	112.3	A282 L284 I288 V289 Q290	A282-Y286 WeakPolarHBondContact O-CB 3.45Å; A282-Y286 PolarHBondContact O-N 3.22Å; L284-Y286 VanDerWaalsContact C-N 3.3Å; L284-Y286 PolarHBondContact O-N 3.29Å; Y286-I288 VanDerWaalsContact C-N 3.32Å; Y286-I288 PolarHBondContact O-N 3.24Å; Y286-V289 PolarHBondContact O-N 3.04Å; Y286-Q290 HydrophobicContact CD1-CG 4.19Å; Y286-Q290 HydrophobicContact CD2-CG 4.22Å; Y286-Q290 HydrophobicContact CE1-CG 3.8Å; Y286-Q290 HydrophobicContact CE2-CG 3.82Å; Y286-Q290 HydrophobicContact CG-CG 4.39Å; Y286-Q290 WeakPolarHBondContact O-CB 3.28Å; Y286-Q290 WeakPolarHBondContact O-CG 3.27Å; Y286-Q290 PolarHBondContact O-N 3.29Å
287	C	98.6	Very high	97.3	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-61.6	-39.6	176.2	-69.1	0	0	0	0	112.6	L242 I249 L268 Q283 L284 A285 F291	L242-C287 PolarHBondContact O-SG 3.19Å; I249-C287 HydrophobicContact CD1-CB 3.85Å; L268-C287 HydrophobicContact CD1-CB 4.1Å; Q283-C287 PolarHBondContact O-N 3.49Å; Q283-C287 VanDerWaalsContact O-N 3.11Å; Q283-C287 PolarHBondContact O-SG 3.41Å; L284-C287 WeakPolarHBondContact O-CA 3.18Å; L284-C287 WeakPolarHBondContact O-CB 3.45Å; L284-C287 PolarHBondContact O-N 3.47Å; A285-C287 VanDerWaalsContact C-N 3.33Å; A285-C287 PolarHBondContact O-N 3.39Å; C287-F291 WeakPolarHBondContact O-CD2 3.35Å; C287-F291 PolarHBondContact O-N 3.22Å
288	I	98.6	Very high	97.4	Very high	0 Å²	0	32.4 Å²	32.4	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-64.4	-52.7	177.6	-63.8	-60.7	0	0	0	110.2	L264 L268 L284 A285 Y286 Q290 F291 L292 V302 I328	L264-I288 HydrophobicContact CD1-CD1 3.43Å; L264-I288 VanDerWaalsContact CD1-CD1 3.43Å; L268-I288 HydrophobicContact CB-CD1 3.84Å; L268-I288 HydrophobicContact CD1-CD1 4.32Å; L284-I288 WeakPolarHBondContact O-CG1 3.47Å; L284-I288 PolarHBondContact O-N 2.94Å; A285-I288 WeakPolarHBondContact O-CB 3.46Å; A285-I288 PolarHBondContact O-N 3.33Å; A285-I288 VanDerWaalsContact O-N 3.07Å; Y286-I288 VanDerWaalsContact C-N 3.32Å; Y286-I288 PolarHBondContact O-N 3.24Å; I288-Q290 VanDerWaalsContact C-N 3.31Å; I288-Q290 PolarHBondContact O-N 3.4Å; I288-F291 WeakPolarHBondContact O-CB 3.49Å; I288-F291 PolarHBondContact O-N 3.44Å; I288-L292 HydrophobicContact CG2-CD1 4.45Å; I288-L292 WeakPolarHBondContact O-CG 3.43Å; I288-L292 PolarHBondContact O-N 2.93Å; I288-L292 VanDerWaalsContact O-N 3.15Å; I288-V302 HydrophobicContact CG2-CG1 3.54Å; I288-I328 HydrophobicContact CG2-CD1 3.91Å; I288-I328 HydrophobicContact CG2-CG1 4.27Å
289	V	98.1	Very high	97.5	Very high	15 Å²	15	30.6 Å²	30.6	9%	0.091	16%	0.164	C	C	.	.	H	α-helix	trans	-56.9	-45.3	178.7	173	0	0	0	0	110.8	A285 Y286 F291 L292 E293 E327 I328 V331	A285-V289 WeakPolarHBondContact O-CG2 3.43Å; A285-V289 PolarHBondContact O-N 2.96Å; Y286-V289 PolarHBondContact O-N 3.04Å; V289-F291 VanDerWaalsContact C-N 3.27Å; V289-F291 PolarHBondContact O-N 3.4Å; V289-L292 PolarHBondContact O-N 2.99Å; V289-E293 HydrophobicContact CG1-CG 4.42Å; V289-E293 PolarHBondContact O-N 3.04Å; V289-E327 HydrophobicContact CG2-CB 4.08Å; V289-I328 HydrophobicContact CG2-CG1 4.33Å; V289-V331 HydrophobicContact CG1-CG1 4.25Å; V289-V331 HydrophobicContact CG1-CG2 4.18Å
290	Q	98	Very high	97.7	Very high	14 Å²	14	29.7 Å²	29.7	7%	0.065	16%	0.158	C	C	.	.	H	α-helix	trans	-58.9	-35.4	176.3	-74	-61	-49.8	0	0	113.1	I249 Y286 I288 E293 K294	I249-Q290 HydrophobicContact CB-CB 4.48Å; I249-Q290 HydrophobicContact CG2-CB 3.84Å; Y286-Q290 HydrophobicContact CD1-CG 4.19Å; Y286-Q290 HydrophobicContact CD2-CG 4.22Å; Y286-Q290 HydrophobicContact CE1-CG 3.8Å; Y286-Q290 HydrophobicContact CE2-CG 3.82Å; Y286-Q290 HydrophobicContact CG-CG 4.39Å; Y286-Q290 WeakPolarHBondContact O-CB 3.28Å; Y286-Q290 WeakPolarHBondContact O-CG 3.27Å; Y286-Q290 PolarHBondContact O-N 3.29Å; I288-Q290 VanDerWaalsContact C-N 3.31Å; I288-Q290 PolarHBondContact O-N 3.4Å; Q290-E293 PolarHBondContact NE2-OE2 3.49Å; Q290-K294 WeakPolarHBondContact O-CG 3.44Å; Q290-K294 PolarHBondContact O-N 3.44Å
291	F	98.1	Very high	97.7	Very high	0 Å²	0	32 Å²	32	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-66.5	-39.7	173.5	-100.1	-71.2	0	0	0	112.5	I249 F252 L256 H260 F263 L264 L268 C287 I288 V289 K294 D295 L298	I249-F291 HydrophobicContact CD1-CD2 3.77Å; I249-F291 HydrophobicContact CD1-CE2 3.43Å; I249-F291 VanDerWaalsContact CD1-CE2 3.43Å; I249-F291 HydrophobicContact CD1-CZ 4.37Å; I249-F291 HydrophobicContact CG1-CD2 4.14Å; I249-F291 HydrophobicContact CG1-CE2 3.62Å; I249-F291 HydrophobicContact CG1-CZ 4.1Å; I249-F291 HydrophobicContact CG2-CD1 4.34Å; I249-F291 HydrophobicContact CG2-CD2 3.79Å; I249-F291 HydrophobicContact CG2-CE2 4.01Å; I249-F291 HydrophobicContact CG2-CG 3.97Å; I249-F291 HydrophobicContact CG2-CZ 4.38Å; F252-F291 HydrophobicContact CD2-CE1 4.33Å; F252-F291 HydrophobicContact CD2-CZ 4.48Å; F252-F291 HydrophobicContact CE2-CE1 4.05Å; F252-F291 AromaticContact CE2-CZ 3.79Å; F252-F291 HydrophobicContact CE2-CZ 3.79Å; L256-F291 HydrophobicContact CD1-CD1 4.1Å; L256-F291 HydrophobicContact CD1-CE1 4.4Å; H260-F291 HydrophobicContact CB-CE1 4.02Å; H260-F291 HydrophobicContact CB-CZ 4.26Å; H260-F291 WeakPolarHBondContact O-CZ 3.35Å; F263-F291 HydrophobicContact CD1-CE2 4.03Å; F263-F291 HydrophobicContact CD1-CZ 4.01Å; F263-F291 HydrophobicContact CE1-CE2 4.28Å; L264-F291 HydrophobicContact CB-CD1 4.4Å; L264-F291 HydrophobicContact CB-CD2 4.29Å; L264-F291 HydrophobicContact CB-CE1 4.33Å; L264-F291 HydrophobicContact CB-CE2 4.21Å; L264-F291 HydrophobicContact CB-CG 4.38Å; L264-F291 HydrophobicContact CB-CZ 4.22Å; L264-F291 HydrophobicContact CD1-CB 4.21Å; L264-F291 HydrophobicContact CD1-CD2 3.91Å; L264-F291 HydrophobicContact CD1-CG 4.11Å; L264-F291 HydrophobicContact CD2-CB 4.03Å; L264-F291 HydrophobicContact CD2-CD1 4.17Å; L264-F291 HydrophobicContact CD2-CG 4.04Å; L264-F291 HydrophobicContact CG-CD2 4.49Å; L264-F291 HydrophobicContact CG-CG 4.41Å; L268-F291 HydrophobicContact CD1-CD2 3.81Å; L268-F291 HydrophobicContact CD1-CE2 3.59Å; C287-F291 WeakPolarHBondContact O-CD2 3.35Å; C287-F291 PolarHBondContact O-N 3.22Å; I288-F291 WeakPolarHBondContact O-CB 3.49Å; I288-F291 PolarHBondContact O-N 3.44Å; V289-F291 VanDerWaalsContact C-N 3.27Å; V289-F291 PolarHBondContact O-N 3.4Å; F291-K294 PolarHBondContact O-N 3.12Å; F291-D295 PolarHBondContact O-N 2.97Å; F291-D295 VanDerWaalsContact O-N 3.1Å; F291-L298 HydrophobicContact CD1-CD1 4.25Å
292	L	97.6	Very high	97.7	Very high	5 Å²	5	31 Å²	31	3%	0.026	17%	0.168	C	C	.	.	H	α-helix	trans	-70.8	-37.8	-178.9	-59.3	-172.8	0	0	0	111.8	I288 V289 K294 D295 L298 T299 V302 I328	I288-L292 HydrophobicContact CG2-CD1 4.45Å; I288-L292 WeakPolarHBondContact O-CG 3.43Å; I288-L292 PolarHBondContact O-N 2.93Å; I288-L292 VanDerWaalsContact O-N 3.15Å; V289-L292 PolarHBondContact O-N 2.99Å; L292-K294 PolarHBondContact O-N 3.19Å; L292-D295 CarbonylContact O-C 3.28Å; L292-D295 VanDerWaalsContact O-C 3.28Å; L292-D295 PolarHBondContact O-N 3.46Å; L292-L298 HydrophobicContact CD2-CB 3.95Å; L292-T299 HydrophobicContact CD1-CG2 4.26Å; L292-V302 HydrophobicContact CD2-CB 4.38Å; L292-V302 HydrophobicContact CD2-CG2 4.01Å; L292-I328 HydrophobicContact CD1-CB 4.24Å; L292-I328 HydrophobicContact CD1-CG1 4Å; L292-I328 HydrophobicContact CD1-CG2 3.46Å; L292-I328 VanDerWaalsContact CD1-CG2 3.46Å
293	E	96.4	Very high	97.6	Very high	106 Å²	106	27.7 Å²	27.7	50%	0.495	14%	0.141	S	C	.	.	H	α-helix	trans	-60.8	-31.5	171.8	-70.8	-174.7	154.9	0	0	112.5	V289 Q290 V331	V289-E293 HydrophobicContact CG1-CG 4.42Å; V289-E293 PolarHBondContact O-N 3.04Å; Q290-E293 PolarHBondContact NE2-OE2 3.49Å; E293-V331 HydrophobicContact CG-CG1 4.46Å
294	K	96.2	Very high	97.6	Very high	49 Å²	49	30.7 Å²	30.7	21%	0.213	15%	0.15	C	C	.	.	H	α-helix	trans	-78.4	-36.5	176.6	-67.5	-57.8	178.2	-160.8	0	113.4	N250 L254 L256 Q290 F291 L292	N250-K294 WeakPolarHBondContact O-CE 3.5Å; N250-K294 PolarHBondContact O-NZ 3.33Å; N250-K294 PolarHBondContact OD1-NZ 3.32Å; N250-K294 VanDerWaalsContact OD1-NZ 3.13Å; L254-K294 HydrophobicContact CD2-CB 4.02Å; L254-K294 HydrophobicContact CD2-CD 4.35Å; L254-K294 VanDerWaalsContact CD2-O 3.26Å; L254-K294 WeakPolarHBondContact CD2-O 3.39Å; L256-K294 HydrophobicContact CD1-CB 4.05Å; L256-K294 HydrophobicContact CD2-CB 4.16Å; L256-K294 HydrophobicContact CG-CB 4.3Å; Q290-K294 WeakPolarHBondContact O-CG 3.44Å; Q290-K294 PolarHBondContact O-N 3.44Å; F291-K294 PolarHBondContact O-N 3.12Å; L292-K294 PolarHBondContact O-N 3.19Å
295	D	96.9	Very high	97.5	Very high	31 Å²	31	31.2 Å²	31.2	17%	0.166	16%	0.156	C	C	.	.			trans	-150.7	93.6	-178.3	-174.3	-7.8	0	0	0	110.6	L256 K261 F291 L292 S297 L298	L256-D295 HydrophobicContact CD1-CB 3.56Å; L256-D295 HydrophobicContact CG-CB 4.28Å; K261-D295 WeakPolarHBondContact CE-OD2 3.29Å; K261-D295 IonicContact NZ-OD2 3.59Å; K261-D295 PolarHBondContact NZ-OD2 3.42Å; F291-D295 PolarHBondContact O-N 2.97Å; F291-D295 VanDerWaalsContact O-N 3.1Å; L292-D295 CarbonylContact O-C 3.28Å; L292-D295 VanDerWaalsContact O-C 3.28Å; L292-D295 PolarHBondContact O-N 3.46Å; D295-S297 VanDerWaalsContact CG-OG 3.27Å; D295-S297 PolarHBondContact O-N 3.3Å; D295-S297 VanDerWaalsContact OD1-CB 3.29Å; D295-S297 WeakPolarHBondContact OD1-CB 3.2Å; D295-S297 PolarHBondContact OD1-N 3.49Å; D295-S297 PolarHBondContact OD1-OG 2.67Å; D295-S297 PolarHBondContact OD2-OG 3.46Å; D295-L298 HydrophobicContact CB-CD1 3.94Å; D295-L298 HydrophobicContact CB-CG 4.13Å; D295-L298 WeakPolarHBondContact O-CB 3.21Å; D295-L298 PolarHBondContact O-N 3.09Å
296	P	96.7	Very high	97.5	Very high	33 Å²	33	31.2 Å²	31.2	21%	0.214	16%	0.156	C	C	.	.	G	3₁₀ helix	trans	-58.2	-21.8	-178.2	-29.1	36.9	0	0	0	114.1	L298 T299 E333 Q336	P296-L298 PolarHBondContact O-N 3.16Å; P296-L298 VanDerWaalsContact O-N 3.12Å; P296-T299 WeakPolarHBondContact O-CB 3.41Å; P296-T299 PolarHBondContact O-N 3.04Å; P296-T299 PolarHBondContact O-OG1 3.26Å; P296-E333 HydrophobicContact CB-CG 4.04Å; P296-E333 HydrophobicContact CG-CG 4.28Å; P296-E333 WeakPolarHBondContact CG-OE1 3.3Å; P296-Q336 HydrophobicContact CB-CG 4.4Å; P296-Q336 WeakPolarHBondContact O-CG 3.46Å
297	S	96.4	Very high	97.4	Very high	58 Å²	58	28.3 Å²	28.3	41%	0.406	15%	0.147	S	C	.	.	G	3₁₀ helix	trans	-63.2	-17.4	176.7	76.1	0	0	0	0	113.5	D295 T299	D295-S297 VanDerWaalsContact CG-OG 3.27Å; D295-S297 PolarHBondContact O-N 3.3Å; D295-S297 VanDerWaalsContact OD1-CB 3.29Å; D295-S297 WeakPolarHBondContact OD1-CB 3.2Å; D295-S297 PolarHBondContact OD1-N 3.49Å; D295-S297 PolarHBondContact OD1-OG 2.67Å; D295-S297 PolarHBondContact OD2-OG 3.46Å; S297-T299 VanDerWaalsContact C-N 3.29Å
298	L	97.5	Very high	97.3	Very high	12 Å²	12	36.1 Å²	36.1	6%	0.063	18%	0.181	C	C	.	.	G	3₁₀ helix	trans	-80	-8	176.8	-60.2	176.7	0	0	0	113.3	L256 K261 L264 F291 L292 D295 P296 E300 P301 V302	L256-L298 HydrophobicContact CD1-CD1 3.78Å; K261-L298 HydrophobicContact CB-CD2 4.47Å; K261-L298 HydrophobicContact CD-CD2 4.03Å; K261-L298 HydrophobicContact CG-CD1 4.32Å; K261-L298 HydrophobicContact CG-CD2 4.1Å; L264-L298 HydrophobicContact CD2-CB 4.02Å; L264-L298 HydrophobicContact CD2-CD1 3.82Å; L264-L298 HydrophobicContact CD2-CG 4.37Å; F291-L298 HydrophobicContact CD1-CD1 4.25Å; L292-L298 HydrophobicContact CD2-CB 3.95Å; D295-L298 HydrophobicContact CB-CD1 3.94Å; D295-L298 HydrophobicContact CB-CG 4.13Å; D295-L298 WeakPolarHBondContact O-CB 3.21Å; D295-L298 PolarHBondContact O-N 3.09Å; P296-L298 PolarHBondContact O-N 3.16Å; P296-L298 VanDerWaalsContact O-N 3.12Å; L298-E300 PolarHBondContact O-N 3.5Å; L298-P301 WeakPolarHBondContact O-CD 3.42Å; L298-P301 VanDerWaalsContact O-CG 3.22Å; L298-P301 WeakPolarHBondContact O-CG 3.41Å; L298-V302 VanDerWaalsContact O-CG2 3.31Å; L298-V302 WeakPolarHBondContact O-CG2 3.26Å; L298-V302 PolarHBondContact O-N 2.61Å
299	T	97.6	Very high	97.2	Very high	2 Å²	2	39 Å²	39	1%	0.012	19%	0.193	C	C	.	.	H	α-helix	trans	-62.9	-44.6	-176.7	-51.9	0	0	0	0	112.2	L292 P296 S297 V302 I303 I328 I332	L292-T299 HydrophobicContact CD1-CG2 4.26Å; P296-T299 WeakPolarHBondContact O-CB 3.41Å; P296-T299 PolarHBondContact O-N 3.04Å; P296-T299 PolarHBondContact O-OG1 3.26Å; S297-T299 VanDerWaalsContact C-N 3.29Å; T299-V302 PolarHBondContact O-N 3.47Å; T299-I303 HydrophobicContact CG2-CG1 4.02Å; T299-I303 WeakPolarHBondContact O-CG1 3.17Å; T299-I303 PolarHBondContact O-N 2.77Å; T299-I328 HydrophobicContact CG2-CG2 4.16Å; T299-I332 HydrophobicContact CG2-CD1 3.56Å; T299-I332 HydrophobicContact CG2-CG1 3.83Å
300	E	96.8	Very high	97.2	Very high	54 Å²	54	39.1 Å²	39.1	25%	0.252	19%	0.192	S	C	.	.	H	α-helix	trans	-57.8	-53.4	179.5	177.5	174.4	-171.8	0	0	113.4	L298 V302 I303 R304 K339 I340	L298-E300 PolarHBondContact O-N 3.5Å; E300-V302 VanDerWaalsContact C-N 3.29Å; E300-V302 PolarHBondContact O-N 3.03Å; E300-I303 PolarHBondContact O-N 3.06Å; E300-R304 HydrophobicContact CG-CG 4.43Å; E300-R304 WeakPolarHBondContact O-CB 3.44Å; E300-R304 VanDerWaalsContact O-CG 3.3Å; E300-R304 WeakPolarHBondContact O-CG 3.29Å; E300-R304 PolarHBondContact O-N 3.03Å; E300-R304 IonicContact OE1-CZ 2.75Å; E300-R304 VanDerWaalsContact OE1-CZ 3.24Å; E300-R304 IonicContact OE1-NE 2.78Å; E300-R304 PolarHBondContact OE1-NE 3.08Å; E300-R304 IonicContact OE1-NH2 3.09Å; E300-R304 PolarHBondContact OE1-NH2 3.22Å; E300-K339 WeakPolarHBondContact OE2-CD 3.2Å; E300-I340 HydrophobicContact CB-CG2 4.11Å; E300-I340 HydrophobicContact CG-CG2 3.9Å
301	P	97.2	Very high	97.1	Very high	52 Å²	52	39.1 Å²	39.1	34%	0.338	19%	0.193	S	C	.	.	H	α-helix	trans	-64.6	-30.9	178	21.6	-31.2	0	0	0	113.3	L298 G305	L298-P301 WeakPolarHBondContact O-CD 3.42Å; L298-P301 VanDerWaalsContact O-CG 3.22Å; L298-P301 WeakPolarHBondContact O-CG 3.41Å; P301-G305 PolarHBondContact O-N 3.28Å
302	V	98.2	Very high	97	Very high	0 Å²	0	48.5 Å²	48.5	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-65	-55.5	174.8	168.1	0	0	0	0	110.9	L264 I269 I288 L292 L298 T299 E300 R304 G305 L306 I328	L264-V302 HydrophobicContact CD1-CG2 4.05Å; L264-V302 HydrophobicContact CD2-CG2 3.79Å; L264-V302 HydrophobicContact CG-CG2 4.09Å; I269-V302 HydrophobicContact CD1-CG2 4.15Å; I288-V302 HydrophobicContact CG2-CG1 3.54Å; L292-V302 HydrophobicContact CD2-CB 4.38Å; L292-V302 HydrophobicContact CD2-CG2 4.01Å; L298-V302 VanDerWaalsContact O-CG2 3.31Å; L298-V302 WeakPolarHBondContact O-CG2 3.26Å; L298-V302 PolarHBondContact O-N 2.61Å; T299-V302 PolarHBondContact O-N 3.47Å; E300-V302 VanDerWaalsContact C-N 3.29Å; E300-V302 PolarHBondContact O-N 3.03Å; V302-R304 PolarHBondContact O-N 2.89Å; V302-G305 CarbonylContact O-C 3.58Å; V302-G305 WeakPolarHBondContact O-CA 3.4Å; V302-G305 PolarHBondContact O-N 3.06Å; V302-L306 HydrophobicContact CG1-CD1 4.28Å; V302-L306 PolarHBondContact O-N 3.35Å; V302-I328 HydrophobicContact CG1-CD1 4.08Å
303	I	97.5	Very high	96.8	Very high	0 Å²	0	55.1 Å²	55.1	0%	0	28%	0.275	C	S	.	.	H	α-helix	trans	-58.6	-47.5	179.8	-65.7	-67.1	0	0	0	110.5	T299 E300 G305 L306 M307 L325 I328 I340	T299-I303 HydrophobicContact CG2-CG1 4.02Å; T299-I303 WeakPolarHBondContact O-CG1 3.17Å; T299-I303 PolarHBondContact O-N 2.77Å; E300-I303 PolarHBondContact O-N 3.06Å; I303-G305 PolarHBondContact O-N 3.12Å; I303-L306 PolarHBondContact O-N 3.03Å; I303-M307 HydrophobicContact CG2-CG 4.27Å; I303-M307 HydrophobicContact CG2-SD 3.97Å; I303-M307 WeakPolarHBondContact O-CB 3.41Å; I303-M307 WeakPolarHBondContact O-CG 3.43Å; I303-M307 PolarHBondContact O-N 3.19Å; I303-L325 HydrophobicContact CD1-CD2 3.31Å; I303-I328 HydrophobicContact CD1-CB 4.42Å; I303-I328 HydrophobicContact CD1-CD1 4.3Å; I303-I328 HydrophobicContact CD1-CG2 3.7Å; I303-I328 HydrophobicContact CG1-CG2 4.35Å; I303-I340 HydrophobicContact CB-CG2 4.4Å; I303-I340 HydrophobicContact CG2-CB 4.14Å; I303-I340 HydrophobicContact CG2-CG1 4.43Å; I303-I340 HydrophobicContact CG2-CG2 4.34Å
304	R	96.8	Very high	96.8	Very high	113 Å²	113	52.2 Å²	52.2	43%	0.426	27%	0.266	S	S	.	.	H	α-helix	trans	-60.5	-34.6	176.5	-69.4	-176	-172.8	-64.8	-3.3	112.3	E300 V302 K308 K339	E300-R304 HydrophobicContact CG-CG 4.43Å; E300-R304 WeakPolarHBondContact O-CB 3.44Å; E300-R304 VanDerWaalsContact O-CG 3.3Å; E300-R304 WeakPolarHBondContact O-CG 3.29Å; E300-R304 PolarHBondContact O-N 3.03Å; E300-R304 IonicContact OE1-CZ 2.75Å; E300-R304 VanDerWaalsContact OE1-CZ 3.24Å; E300-R304 IonicContact OE1-NE 2.78Å; E300-R304 PolarHBondContact OE1-NE 3.08Å; E300-R304 IonicContact OE1-NH2 3.09Å; E300-R304 PolarHBondContact OE1-NH2 3.22Å; V302-R304 PolarHBondContact O-N 2.89Å; R304-K308 WeakPolarHBondContact O-CB 3.45Å; R304-K308 PolarHBondContact O-N 3.28Å; R304-K339 PolarHBondContact NH2-O 2.86Å
305	G	97.5	Very high	96.7	Very high	12 Å²	12	51.7 Å²	51.7	12%	0.124	27%	0.268	C	S	.	.	H	α-helix	trans	-64.3	-50.7	174.2	0	0	0	0	0	113	P301 V302 I303 M307 K308 F309	P301-G305 PolarHBondContact O-N 3.28Å; V302-G305 CarbonylContact O-C 3.58Å; V302-G305 WeakPolarHBondContact O-CA 3.4Å; V302-G305 PolarHBondContact O-N 3.06Å; I303-G305 PolarHBondContact O-N 3.12Å; G305-M307 VanDerWaalsContact C-N 3.33Å; G305-M307 PolarHBondContact O-N 3.41Å; G305-K308 WeakPolarHBondContact O-CB 3.22Å; G305-K308 PolarHBondContact O-N 3.01Å; G305-F309 WeakPolarHBondContact O-CD2 3.38Å; G305-F309 PolarHBondContact O-N 2.68Å; G305-F309 VanDerWaalsContact O-N 3.15Å
306	L	97.9	Very high	96.7	Very high	0 Å²	0	55.3 Å²	55.3	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-59.5	-44.3	175.8	-67.7	177	0	0	0	111.3	V302 I303 K308 F309 W310 F321 L325 I328	V302-L306 HydrophobicContact CG1-CD1 4.28Å; V302-L306 PolarHBondContact O-N 3.35Å; I303-L306 PolarHBondContact O-N 3.03Å; L306-K308 VanDerWaalsContact C-N 3.31Å; L306-K308 PolarHBondContact O-N 3.24Å; L306-F309 CarbonylContact O-C 3.6Å; L306-F309 PolarHBondContact O-N 3.26Å; L306-F309 VanDerWaalsContact O-N 3.09Å; L306-W310 PolarHBondContact O-N 3.39Å; L306-F321 HydrophobicContact CD2-CE1 4.31Å; L306-L325 HydrophobicContact CD1-CD2 4Å; L306-I328 HydrophobicContact CD1-CD1 3.6Å
307	M	96.6	Very high	96.7	Very high	39 Å²	39	54.9 Å²	54.9	19%	0.192	28%	0.279	C	S	.	.	H	α-helix	trans	-63.4	-35.8	177.2	-66.8	-174.4	89.8	0	0	113	I303 G305 F309 W310 P343 Q347	I303-M307 HydrophobicContact CG2-CG 4.27Å; I303-M307 HydrophobicContact CG2-SD 3.97Å; I303-M307 WeakPolarHBondContact O-CB 3.41Å; I303-M307 WeakPolarHBondContact O-CG 3.43Å; I303-M307 PolarHBondContact O-N 3.19Å; G305-M307 VanDerWaalsContact C-N 3.33Å; G305-M307 PolarHBondContact O-N 3.41Å; M307-F309 VanDerWaalsContact C-N 3.28Å; M307-F309 PolarHBondContact O-N 2.56Å; M307-W310 WeakPolarHBondContact O-CB 3.19Å; M307-W310 PolarHBondContact O-N 3.47Å; M307-P343 HydrophobicContact CE-CB 3.92Å; M307-P343 WeakPolarHBondContact CE-O 3.37Å; M307-P343 HydrophobicContact SD-CB 3.93Å; M307-Q347 HydrophobicContact CE-CB 3.53Å; M307-Q347 HydrophobicContact CE-CG 4.32Å
308	K	96.6	Very high	96.8	Very high	164 Å²	164	53.3 Å²	53.3	71%	0.713	27%	0.265	S	S	*	.	H	α-helix	trans	-63.4	-37.1	174.2	177.6	-174.9	173.9	-173.8	0	111.5	R304 G305 L306	R304-K308 WeakPolarHBondContact O-CB 3.45Å; R304-K308 PolarHBondContact O-N 3.28Å; G305-K308 WeakPolarHBondContact O-CB 3.22Å; G305-K308 PolarHBondContact O-N 3.01Å; L306-K308 VanDerWaalsContact C-N 3.31Å; L306-K308 PolarHBondContact O-N 3.24Å
309	F	96.8	Very high	96.8	Very high	60 Å²	60	54.6 Å²	54.6	26%	0.263	27%	0.273	S	S	.	.	T	Hydrogen-bonded Turn	trans	-96.6	14.5	-178.5	-62.4	-44.3	0	0	0	114	I269 P270 T273 G305 L306 M307	I269-F309 HydrophobicContact CG2-CD2 3.88Å; I269-F309 HydrophobicContact CG2-CE2 3.86Å; P270-F309 HydrophobicContact CG-CE2 4.41Å; T273-F309 HydrophobicContact CG2-CB 3.97Å; T273-F309 HydrophobicContact CG2-CD1 3.5Å; T273-F309 VanDerWaalsContact CG2-CD1 3.5Å; T273-F309 HydrophobicContact CG2-CD2 3.91Å; T273-F309 HydrophobicContact CG2-CE1 3.86Å; T273-F309 HydrophobicContact CG2-CE2 4.23Å; T273-F309 HydrophobicContact CG2-CG 3.53Å; T273-F309 HydrophobicContact CG2-CZ 4.21Å; G305-F309 WeakPolarHBondContact O-CD2 3.38Å; G305-F309 PolarHBondContact O-N 2.68Å; G305-F309 VanDerWaalsContact O-N 3.15Å; L306-F309 CarbonylContact O-C 3.6Å; L306-F309 PolarHBondContact O-N 3.26Å; L306-F309 VanDerWaalsContact O-N 3.09Å; M307-F309 VanDerWaalsContact C-N 3.28Å; M307-F309 PolarHBondContact O-N 2.56Å
310	W	97.9	Very high	96.8	Very high	18 Å²	18	55.8 Å²	55.8	7%	0.068	28%	0.279	C	S	.	.			trans	-53	125.5	-177.1	-163.1	-89.6	0	0	0	111.9	L306 M307 K312 E318 F321 L322 L325 Q347 C351	L306-W310 PolarHBondContact O-N 3.39Å; M307-W310 WeakPolarHBondContact O-CB 3.19Å; M307-W310 PolarHBondContact O-N 3.47Å; W310-K312 PolarHBondContact O-N 3.34Å; W310-E318 HydrophobicContact CZ2-CG 3.92Å; W310-E318 PolarHBondContact NE1-OE1 2.83Å; W310-F321 HydrophobicContact CD2-CD1 4.43Å; W310-F321 HydrophobicContact CE3-CB 4.3Å; W310-F321 AromaticContact CE3-CD1 3.76Å; W310-F321 HydrophobicContact CE3-CD1 3.76Å; W310-F321 HydrophobicContact CE3-CG 4.47Å; W310-F321 HydrophobicContact CH2-CB 3.87Å; W310-F321 HydrophobicContact CZ2-CB 4.44Å; W310-F321 HydrophobicContact CZ3-CB 3.77Å; W310-F321 AromaticContact CZ3-CD1 3.96Å; W310-F321 HydrophobicContact CZ3-CD1 3.96Å; W310-F321 HydrophobicContact CZ3-CG 4.37Å; W310-L322 HydrophobicContact CH2-CD2 3.85Å; W310-L322 HydrophobicContact CH2-CG 4.02Å; W310-L322 HydrophobicContact CZ2-CD2 4.09Å; W310-L322 HydrophobicContact CZ2-CG 4.11Å; W310-L325 HydrophobicContact CH2-CD1 3.72Å; W310-L325 HydrophobicContact CZ3-CD1 3.42Å; W310-L325 VanDerWaalsContact CZ3-CD1 3.42Å; W310-L325 HydrophobicContact CZ3-CG 4.31Å; W310-Q347 VanDerWaalsContact CD1-NE2 3.32Å; W310-Q347 HydrophobicContact CD2-CG 3.85Å; W310-Q347 VanDerWaalsContact CE2-NE2 3.35Å; W310-Q347 HydrophobicContact CE3-CG 4.09Å; W310-Q347 HydrophobicContact CG-CG 4.38Å; W310-Q347 HydrophobicContact CH2-CG 4.38Å; W310-Q347 HydrophobicContact CZ2-CG 4.16Å; W310-Q347 HydrophobicContact CZ3-CG 4.35Å; W310-C351 WeakPolarHBondContact CZ2-SG 3.38Å
311	P	96.8	Very high	96.9	Very high	14 Å²	14	53.3 Å²	53.3	9%	0.091	27%	0.268	C	S	.	.			trans	-62	129.2	179.8	-22.1	33.2	0	0	0	111.1	K317 F321	P311-K317 HydrophobicContact CB-CB 3.85Å; P311-K317 HydrophobicContact CG-CB 3.58Å; P311-F321 HydrophobicContact CG-CD1 4.4Å; P311-F321 HydrophobicContact CG-CD2 3.72Å; P311-F321 HydrophobicContact CG-CE1 4.34Å; P311-F321 HydrophobicContact CG-CE2 3.63Å; P311-F321 HydrophobicContact CG-CG 4.09Å; P311-F321 HydrophobicContact CG-CZ 3.94Å
312	K	95	Very high	96.9	Very high	196 Å²	196	50.8 Å²	50.8	85%	0.852	25%	0.251	S	S	*	.	S	Bend	trans	-109.7	-13.5	178.5	-60.7	-177.1	-173.8	174.5	0	113.8	W310	W310-K312 PolarHBondContact O-N 3.34Å
313	T	94.1	Very high	96.9	Very high	145 Å²	145	51.3 Å²	51.3	89%	0.89	26%	0.257	S	S	*	.	S	Bend	trans	-128.1	-4.7	-171	54.8	0	0	0	0	113.5
314	C	94.9	Very high	97	Very high	44 Å²	44	51.3 Å²	51.3	30%	0.297	26%	0.257	S	S	.	.			trans	-131.1	105.4	179.8	-179.9	0	0	0	0	109.8	Q316 K317 E318	C314-Q316 VanDerWaalsContact C-N 3.34Å; C314-K317 HydrophobicContact CB-CB 4.16Å; C314-K317 HydrophobicContact CB-CD 4.35Å; C314-K317 HydrophobicContact CB-CG 4.25Å; C314-K317 PolarHBondContact O-N 3.33Å; C314-E318 PolarHBondContact O-N 2.93Å; C314-E318 VanDerWaalsContact O-N 3.09Å
315	S	95.8	Very high	97	Very high	38 Å²	38	46 Å²	46	27%	0.266	24%	0.237	S	C	.	.	H	α-helix	trans	-67.9	-32.3	-178.2	-59.9	0	0	0	0	112.7	E318 V319 H356	S315-E318 WeakPolarHBondContact O-CB 3.46Å; S315-E318 PolarHBondContact O-N 3.33Å; S315-V319 WeakPolarHBondContact O-CG2 3.41Å; S315-V319 PolarHBondContact O-N 2.98Å; S315-H356 PolarHBondContact OG-CD2 2.94Å
316	Q	95.6	Very high	97.1	Very high	107 Å²	107	47 Å²	47	50%	0.5	24%	0.238	S	C	.	.	H	α-helix	trans	-61.1	-47.3	174.3	-173.9	-179.6	2.2	0	0	111	C314 E318 V319 M320	C314-Q316 VanDerWaalsContact C-N 3.34Å; Q316-E318 VanDerWaalsContact C-N 3.29Å; Q316-E318 PolarHBondContact O-N 3.38Å; Q316-V319 PolarHBondContact O-N 3.24Å; Q316-M320 HydrophobicContact CG-SD 4.37Å; Q316-M320 VanDerWaalsContact O-CG 3.26Å; Q316-M320 WeakPolarHBondContact O-CG 3.23Å; Q316-M320 PolarHBondContact O-N 3.29Å
317	K	97.1	Very high	97	Very high	25 Å²	25	51.5 Å²	51.5	11%	0.109	26%	0.259	C	S	.	.	H	α-helix	trans	-62	-37	173.3	-72.4	-172.8	63.1	165.7	0	112.1	H272 T273 V274 P311 C314 M320 F321	H272-K317 WeakPolarHBondContact O-CE 3.29Å; H272-K317 PolarHBondContact O-NZ 2.64Å; T273-K317 PolarHBondContact O-NZ 3.49Å; T273-K317 VanDerWaalsContact O-NZ 3.08Å; V274-K317 PolarHBondContact O-NZ 2.98Å; P311-K317 HydrophobicContact CB-CB 3.85Å; P311-K317 HydrophobicContact CG-CB 3.58Å; C314-K317 HydrophobicContact CB-CB 4.16Å; C314-K317 HydrophobicContact CB-CD 4.35Å; C314-K317 HydrophobicContact CB-CG 4.25Å; C314-K317 PolarHBondContact O-N 3.33Å; K317-M320 WeakPolarHBondContact O-CB 3.1Å; K317-M320 PolarHBondContact O-N 3.02Å; K317-F321 WeakPolarHBondContact O-CD2 3.33Å; K317-F321 PolarHBondContact O-N 3.17Å
318	E	97.9	Very high	97.1	Very high	25 Å²	25	49.6 Å²	49.6	12%	0.117	25%	0.25	C	S	.	.	H	α-helix	trans	-62.7	-41.5	176.2	-172.7	168.2	-150.9	0	0	112	W310 C314 S315 Q316 M320 F321 L322 V359	W310-E318 HydrophobicContact CZ2-CG 3.92Å; W310-E318 PolarHBondContact NE1-OE1 2.83Å; C314-E318 PolarHBondContact O-N 2.93Å; C314-E318 VanDerWaalsContact O-N 3.09Å; S315-E318 WeakPolarHBondContact O-CB 3.46Å; S315-E318 PolarHBondContact O-N 3.33Å; Q316-E318 VanDerWaalsContact C-N 3.29Å; Q316-E318 PolarHBondContact O-N 3.38Å; E318-M320 VanDerWaalsContact C-N 3.32Å; E318-M320 PolarHBondContact O-N 3.07Å; E318-F321 PolarHBondContact O-N 3.02Å; E318-L322 WeakPolarHBondContact O-CG 3.39Å; E318-L322 PolarHBondContact O-N 3.35Å; E318-V359 HydrophobicContact CB-CG2 4.15Å; E318-V359 VanDerWaalsContact CD-CG1 3.49Å; E318-V359 HydrophobicContact CG-CG1 3.82Å; E318-V359 HydrophobicContact CG-CG2 4.12Å
319	V	98.1	Very high	97.2	Very high	38 Å²	38	41.8 Å²	41.8	23%	0.23	22%	0.216	C	C	.	.	H	α-helix	trans	-61.8	-40	172.8	172.7	0	0	0	0	111.4	S315 Q316 L322 G323 Q358 V359 R362	S315-V319 WeakPolarHBondContact O-CG2 3.41Å; S315-V319 PolarHBondContact O-N 2.98Å; Q316-V319 PolarHBondContact O-N 3.24Å; V319-L322 PolarHBondContact O-N 3.33Å; V319-G323 PolarHBondContact O-N 3.33Å; V319-Q358 HydrophobicContact CG2-CB 4.05Å; V319-V359 HydrophobicContact CG2-CG2 3.95Å; V319-R362 HydrophobicContact CG1-CB 4.32Å; V319-R362 HydrophobicContact CG1-CG 4.09Å
320	M	98	Very high	97.2	Very high	28 Å²	28	42.6 Å²	42.6	14%	0.138	22%	0.223	C	C	.	.	H	α-helix	trans	-64.8	-45.1	177.1	-64.5	163	65.6	0	0	112.1	L277 S278 H281 Q316 K317 E318 L322 G323 E324	L277-M320 HydrophobicContact CB-CE 4.33Å; L277-M320 HydrophobicContact CD2-CE 4.14Å; L277-M320 HydrophobicContact CG-CE 3.78Å; S278-M320 VanDerWaalsContact CA-CE 3.45Å; H281-M320 HydrophobicContact CB-CE 3.15Å; H281-M320 PolarHBondContact CE1-O 3.48Å; H281-M320 PolarHBondContact NE2-O 3.21Å; Q316-M320 HydrophobicContact CG-SD 4.37Å; Q316-M320 VanDerWaalsContact O-CG 3.26Å; Q316-M320 WeakPolarHBondContact O-CG 3.23Å; Q316-M320 PolarHBondContact O-N 3.29Å; K317-M320 WeakPolarHBondContact O-CB 3.1Å; K317-M320 PolarHBondContact O-N 3.02Å; E318-M320 VanDerWaalsContact C-N 3.32Å; E318-M320 PolarHBondContact O-N 3.07Å; M320-L322 VanDerWaalsContact C-N 3.31Å; M320-L322 PolarHBondContact O-N 2.94Å; M320-G323 CarbonylContact O-C 3.37Å; M320-G323 VanDerWaalsContact O-CA 3.31Å; M320-G323 WeakPolarHBondContact O-CA 3.47Å; M320-G323 PolarHBondContact O-N 3.23Å; M320-E324 PolarHBondContact O-N 2.88Å
321	F	98.4	Very high	97.1	Very high	1 Å²	1	44.3 Å²	44.3	0%	0.004	24%	0.235	C	C	.	.	H	α-helix	trans	-61.1	-38.8	175.2	-87.8	-124	0	0	0	112.1	H272 L277 L306 W310 P311 K317 E318 G323 L325	H272-F321 HydrophobicContact CB-CE2 4.1Å; H272-F321 HydrophobicContact CB-CZ 3.67Å; L277-F321 HydrophobicContact CD2-CD2 4.34Å; L277-F321 HydrophobicContact CD2-CE2 3.73Å; L306-F321 HydrophobicContact CD2-CE1 4.31Å; W310-F321 HydrophobicContact CD2-CD1 4.43Å; W310-F321 HydrophobicContact CE3-CB 4.3Å; W310-F321 AromaticContact CE3-CD1 3.76Å; W310-F321 HydrophobicContact CE3-CD1 3.76Å; W310-F321 HydrophobicContact CE3-CG 4.47Å; W310-F321 HydrophobicContact CH2-CB 3.87Å; W310-F321 HydrophobicContact CZ2-CB 4.44Å; W310-F321 HydrophobicContact CZ3-CB 3.77Å; W310-F321 AromaticContact CZ3-CD1 3.96Å; W310-F321 HydrophobicContact CZ3-CD1 3.96Å; W310-F321 HydrophobicContact CZ3-CG 4.37Å; P311-F321 HydrophobicContact CG-CD1 4.4Å; P311-F321 HydrophobicContact CG-CD2 3.72Å; P311-F321 HydrophobicContact CG-CE1 4.34Å; P311-F321 HydrophobicContact CG-CE2 3.63Å; P311-F321 HydrophobicContact CG-CG 4.09Å; P311-F321 HydrophobicContact CG-CZ 3.94Å; K317-F321 WeakPolarHBondContact O-CD2 3.33Å; K317-F321 PolarHBondContact O-N 3.17Å; E318-F321 PolarHBondContact O-N 3.02Å; F321-G323 VanDerWaalsContact C-N 3.3Å; F321-L325 VanDerWaalsContact O-CB 3.28Å; F321-L325 WeakPolarHBondContact O-CB 3.44Å; F321-L325 VanDerWaalsContact O-CG 3.3Å; F321-L325 WeakPolarHBondContact O-CG 3.4Å; F321-L325 PolarHBondContact O-N 3.38Å
322	L	98.3	Very high	97.1	Very high	0 Å²	0	43.7 Å²	43.7	0%	0	23%	0.231	C	C	.	.	H	α-helix	trans	-65.3	-35.6	171.8	-70.7	166.9	0	0	0	111.5	W310 E318 V319 M320 E326 I348 C351 V359 R362 A363 Y366	W310-L322 HydrophobicContact CH2-CD2 3.85Å; W310-L322 HydrophobicContact CH2-CG 4.02Å; W310-L322 HydrophobicContact CZ2-CD2 4.09Å; W310-L322 HydrophobicContact CZ2-CG 4.11Å; E318-L322 WeakPolarHBondContact O-CG 3.39Å; E318-L322 PolarHBondContact O-N 3.35Å; V319-L322 PolarHBondContact O-N 3.33Å; M320-L322 VanDerWaalsContact C-N 3.31Å; M320-L322 PolarHBondContact O-N 2.94Å; L322-E326 PolarHBondContact O-N 3.39Å; L322-E326 VanDerWaalsContact O-N 3.15Å; L322-I348 HydrophobicContact CD2-CD1 3.65Å; L322-C351 HydrophobicContact CD1-CB 4.23Å; L322-C351 HydrophobicContact CD2-CB 4.22Å; L322-V359 HydrophobicContact CD1-CG1 4.07Å; L322-R362 HydrophobicContact CB-CG 3.67Å; L322-R362 HydrophobicContact CD1-CB 4.13Å; L322-R362 HydrophobicContact CD1-CG 4.17Å; L322-A363 HydrophobicContact CD1-CB 4.04Å; L322-A363 HydrophobicContact CD2-CB 4.15Å; L322-Y366 WeakPolarHBondContact CA-OH 3.38Å; L322-Y366 PolarHBondContact O-OH 3.04Å
323	G	98	Very high	97.2	Very high	11 Å²	11	38.6 Å²	38.6	11%	0.113	21%	0.21	C	C	.	.	H	α-helix	trans	-57.7	-56.8	171.4	0	0	0	0	0	112.9	V319 M320 F321 L325 E326 E327	V319-G323 PolarHBondContact O-N 3.33Å; M320-G323 CarbonylContact O-C 3.37Å; M320-G323 VanDerWaalsContact O-CA 3.31Å; M320-G323 WeakPolarHBondContact O-CA 3.47Å; M320-G323 PolarHBondContact O-N 3.23Å; F321-G323 VanDerWaalsContact C-N 3.3Å; G323-L325 VanDerWaalsContact C-N 3.34Å; G323-L325 PolarHBondContact O-N 3.01Å; G323-E326 PolarHBondContact O-N 3.36Å; G323-E327 PolarHBondContact O-N 2.98Å
324	E	98.4	Very high	97.4	Very high	0 Å²	0	34.3 Å²	34.3	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-62.7	-40	-179.5	-178.1	-176.1	176.1	0	0	112.3	H272 H281 A285 M320 E326 E327 I328	H272-E324 IonicContact CD2-OE2 3.74Å; H272-E324 PolarHBondContact CD2-OE2 3.23Å; H272-E324 IonicContact CE1-OE1 3.09Å; H272-E324 IonicContact NE2-OE1 3.81Å; H272-E324 PolarHBondContact NE2-OE1 3.23Å; H272-E324 VanDerWaalsContact NE2-OE1 3.15Å; H272-E324 IonicContact NE2-OE2 2.85Å; H272-E324 PolarHBondContact NE2-OE2 3Å; H281-E324 IonicContact NE2-OE2 2.76Å; A285-E324 HydrophobicContact CB-CB 4.24Å; A285-E324 HydrophobicContact CB-CG 3.82Å; M320-E324 PolarHBondContact O-N 2.88Å; E324-E326 VanDerWaalsContact C-N 3.3Å; E324-E326 PolarHBondContact O-N 3.11Å; E324-E327 PolarHBondContact O-N 3.02Å; E324-I328 HydrophobicContact CG-CD1 3.96Å; E324-I328 WeakPolarHBondContact O-CG1 3.47Å; E324-I328 PolarHBondContact O-N 3.27Å
325	L	98.1	Very high	97.5	Very high	1 Å²	1	35.3 Å²	35.3	1%	0.005	19%	0.193	C	C	.	.	H	α-helix	trans	-62.2	-36.9	176.8	-83.5	-175.1	0	0	0	112.4	I303 L306 W310 F321 G323 I328 L329 L344 Y366	I303-L325 HydrophobicContact CD1-CD2 3.31Å; L306-L325 HydrophobicContact CD1-CD2 4Å; W310-L325 HydrophobicContact CH2-CD1 3.72Å; W310-L325 HydrophobicContact CZ3-CD1 3.42Å; W310-L325 VanDerWaalsContact CZ3-CD1 3.42Å; W310-L325 HydrophobicContact CZ3-CG 4.31Å; F321-L325 VanDerWaalsContact O-CB 3.28Å; F321-L325 WeakPolarHBondContact O-CB 3.44Å; F321-L325 VanDerWaalsContact O-CG 3.3Å; F321-L325 WeakPolarHBondContact O-CG 3.4Å; F321-L325 PolarHBondContact O-N 3.38Å; G323-L325 VanDerWaalsContact C-N 3.34Å; G323-L325 PolarHBondContact O-N 3.01Å; L325-I328 PolarHBondContact O-N 3.08Å; L325-L329 WeakPolarHBondContact O-CB 3.13Å; L325-L329 WeakPolarHBondContact O-CG 3.5Å; L325-L329 PolarHBondContact O-N 3.42Å; L325-L344 HydrophobicContact CD1-CD1 3.91Å; L325-L344 HydrophobicContact CD2-CD1 4.37Å; L325-Y366 WeakPolarHBondContact CB-OH 3.47Å
326	E	97.9	Very high	97.6	Very high	33 Å²	33	34.3 Å²	34.3	15%	0.154	18%	0.184	C	C	.	.	H	α-helix	trans	-63.4	-47.4	173.8	-175.2	173.8	-171.6	0	0	111	L322 G323 E324 I328 L329 D330 R362 Y366 N369 I372	L322-E326 PolarHBondContact O-N 3.39Å; L322-E326 VanDerWaalsContact O-N 3.15Å; G323-E326 PolarHBondContact O-N 3.36Å; E324-E326 VanDerWaalsContact C-N 3.3Å; E324-E326 PolarHBondContact O-N 3.11Å; E326-I328 VanDerWaalsContact C-N 3.27Å; E326-I328 PolarHBondContact O-N 3.05Å; E326-L329 PolarHBondContact O-N 3.45Å; E326-D330 PolarHBondContact O-N 2.9Å; E326-R362 IonicContact OE2-CZ 2.74Å; E326-R362 IonicContact OE2-NH1 3.37Å; E326-R362 PolarHBondContact OE2-NH1 2.95Å; E326-R362 IonicContact OE2-NH2 3.12Å; E326-R362 PolarHBondContact OE2-NH2 3.23Å; E326-Y366 HydrophobicContact CB-CD1 4.47Å; E326-Y366 HydrophobicContact CB-CE1 3.92Å; E326-Y366 PolarHBondContact N-OH 3.18Å; E326-N369 PolarHBondContact OE1-ND2 3.35Å; E326-I372 HydrophobicContact CG-CD1 3.88Å
327	E	97.7	Very high	97.7	Very high	94 Å²	94	29.2 Å²	29.2	44%	0.439	16%	0.16	S	C	.	.	H	α-helix	trans	-59.5	-37	177.2	-66.6	-179.6	-146.8	0	0	112.5	V289 G323 E324 D330	V289-E327 HydrophobicContact CG2-CB 4.08Å; G323-E327 PolarHBondContact O-N 2.98Å; E324-E327 PolarHBondContact O-N 3.02Å; E327-D330 PolarHBondContact O-N 3.19Å
328	I	98.2	Very high	97.7	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-67.9	-40.6	174.5	-68.5	166.1	0	0	0	111.3	I288 V289 L292 T299 V302 I303 L306 E324 L325 E326 D330 V331 I332	I288-I328 HydrophobicContact CG2-CD1 3.91Å; I288-I328 HydrophobicContact CG2-CG1 4.27Å; V289-I328 HydrophobicContact CG2-CG1 4.33Å; L292-I328 HydrophobicContact CD1-CB 4.24Å; L292-I328 HydrophobicContact CD1-CG1 4Å; L292-I328 HydrophobicContact CD1-CG2 3.46Å; L292-I328 VanDerWaalsContact CD1-CG2 3.46Å; T299-I328 HydrophobicContact CG2-CG2 4.16Å; V302-I328 HydrophobicContact CG1-CD1 4.08Å; I303-I328 HydrophobicContact CD1-CB 4.42Å; I303-I328 HydrophobicContact CD1-CD1 4.3Å; I303-I328 HydrophobicContact CD1-CG2 3.7Å; I303-I328 HydrophobicContact CG1-CG2 4.35Å; L306-I328 HydrophobicContact CD1-CD1 3.6Å; E324-I328 HydrophobicContact CG-CD1 3.96Å; E324-I328 WeakPolarHBondContact O-CG1 3.47Å; E324-I328 PolarHBondContact O-N 3.27Å; L325-I328 PolarHBondContact O-N 3.08Å; E326-I328 VanDerWaalsContact C-N 3.27Å; E326-I328 PolarHBondContact O-N 3.05Å; I328-D330 VanDerWaalsContact C-N 3.27Å; I328-D330 PolarHBondContact O-N 3.42Å; I328-V331 WeakPolarHBondContact O-CG2 3.43Å; I328-V331 PolarHBondContact O-N 3.07Å; I328-I332 PolarHBondContact O-N 3.28Å; I328-I332 VanDerWaalsContact O-N 3.16Å
329	L	97.9	Very high	97.7	Very high	0 Å²	0	35 Å²	35	0%	0	19%	0.191	C	C	.	.	H	α-helix	trans	-68.6	-26.9	178.8	-71.9	171.3	0	0	0	112.2	L325 E326 V331 I332 F337 L344 Y366 Y371 I372	L325-L329 WeakPolarHBondContact O-CB 3.13Å; L325-L329 WeakPolarHBondContact O-CG 3.5Å; L325-L329 PolarHBondContact O-N 3.42Å; E326-L329 PolarHBondContact O-N 3.45Å; L329-V331 PolarHBondContact O-N 3.46Å; L329-I332 HydrophobicContact CD2-CD1 4.27Å; L329-I332 HydrophobicContact CD2-CG2 4.14Å; L329-I332 WeakPolarHBondContact O-CG2 3.3Å; L329-I332 PolarHBondContact O-N 2.96Å; L329-F337 HydrophobicContact CD2-CD2 3.96Å; L329-F337 HydrophobicContact CD2-CE2 4.06Å; L329-L344 HydrophobicContact CD1-CD2 4.05Å; L329-L344 HydrophobicContact CD2-CD2 3.75Å; L329-L344 HydrophobicContact CG-CD2 4.41Å; L329-Y366 HydrophobicContact CD1-CD2 4.12Å; L329-Y366 HydrophobicContact CD1-CE2 3.72Å; L329-Y371 WeakPolarHBondContact O-CD1 3.49Å; L329-Y371 VanDerWaalsContact O-CE1 3.27Å; L329-Y371 WeakPolarHBondContact O-CE1 3.28Å; L329-I372 HydrophobicContact CB-CD1 3.81Å; L329-I372 HydrophobicContact CB-CG1 3.9Å; L329-I372 HydrophobicContact CD1-CD1 3.94Å; L329-I372 HydrophobicContact CD1-CG1 4.42Å
330	D	96.5	Very high	97.6	Very high	76 Å²	76	33.2 Å²	33.2	41%	0.406	18%	0.18	S	C	.	.	H	α-helix	trans	-65.4	-25	174.7	-83.3	-7.6	0	0	0	113.8	E326 E327 I328 N369	E326-D330 PolarHBondContact O-N 2.9Å; E327-D330 PolarHBondContact O-N 3.19Å; I328-D330 VanDerWaalsContact C-N 3.27Å; I328-D330 PolarHBondContact O-N 3.42Å; D330-N369 PolarHBondContact OD1-ND2 3.09Å; D330-N369 PolarHBondContact OD1-OD1 3.44Å; D330-N369 PolarHBondContact OD2-ND2 2.99Å
331	V	96.4	Very high	97.6	Very high	54 Å²	54	32.4 Å²	32.4	33%	0.327	18%	0.176	S	C	.	.	T	Hydrogen-bonded Turn	trans	-110.5	1.7	180	-58.5	0	0	0	0	113.5	V289 E293 I328 L329	V289-V331 HydrophobicContact CG1-CG1 4.25Å; V289-V331 HydrophobicContact CG1-CG2 4.18Å; E293-V331 HydrophobicContact CG-CG1 4.46Å; I328-V331 WeakPolarHBondContact O-CG2 3.43Å; I328-V331 PolarHBondContact O-N 3.07Å; L329-V331 PolarHBondContact O-N 3.46Å
332	I	97.9	Very high	97.6	Very high	2 Å²	2	37 Å²	37	1%	0.01	20%	0.198	C	C	.	.			trans	-71.4	135.7	-177.1	-163.1	165.3	0	0	0	111	T299 I328 L329 Q336 F337 I340 Y371 L375	T299-I332 HydrophobicContact CG2-CD1 3.56Å; T299-I332 HydrophobicContact CG2-CG1 3.83Å; I328-I332 PolarHBondContact O-N 3.28Å; I328-I332 VanDerWaalsContact O-N 3.16Å; L329-I332 HydrophobicContact CD2-CD1 4.27Å; L329-I332 HydrophobicContact CD2-CG2 4.14Å; L329-I332 WeakPolarHBondContact O-CG2 3.3Å; L329-I332 PolarHBondContact O-N 2.96Å; I332-Q336 HydrophobicContact CD1-CB 4.36Å; I332-Q336 HydrophobicContact CG1-CB 4Å; I332-F337 HydrophobicContact CD1-CB 3.94Å; I332-F337 HydrophobicContact CD1-CD2 4.32Å; I332-F337 HydrophobicContact CG1-CB 4.26Å; I332-F337 HydrophobicContact CG2-CB 4.28Å; I332-F337 HydrophobicContact CG2-CD2 4.39Å; I332-I340 HydrophobicContact CD1-CD1 4.09Å; I332-I340 HydrophobicContact CD1-CG1 4.18Å; I332-Y371 HydrophobicContact CG2-CE1 4.27Å; I332-Y371 WeakPolarHBondContact O-CE1 3.42Å; I332-Y371 PolarHBondContact O-OH 3.26Å; I332-L375 HydrophobicContact CG2-CD1 3.64Å
333	E	97	Very high	97.5	Very high	88 Å²	88	38.8 Å²	38.8	41%	0.411	21%	0.209	S	C	.	.			trans	-75.1	143.2	167.1	-66.8	-177.5	175.2	0	0	110.9	P296 S335 Q336 F337	P296-E333 HydrophobicContact CB-CG 4.04Å; P296-E333 HydrophobicContact CG-CG 4.28Å; P296-E333 WeakPolarHBondContact CG-OE1 3.3Å; E333-S335 PolarHBondContact O-N 3.47Å; E333-S335 PolarHBondContact OE2-OG 3.02Å; E333-Q336 HydrophobicContact CB-CG 4.28Å; E333-Q336 PolarHBondContact O-N 3.23Å; E333-F337 PolarHBondContact O-N 3.39Å
334	P	97.3	Very high	97.5	Very high	56 Å²	56	38.3 Å²	38.3	36%	0.364	20%	0.204	S	C	.	.	H	α-helix	trans	-52.9	-35.6	176.7	-27.3	34.1	0	0	0	113.1	Q336 F337 V338 L375	P334-Q336 VanDerWaalsContact C-N 3.27Å; P334-Q336 PolarHBondContact O-N 2.93Å; P334-F337 PolarHBondContact O-N 2.92Å; P334-V338 WeakPolarHBondContact O-CG2 3.46Å; P334-V338 PolarHBondContact O-N 2.89Å; P334-L375 HydrophobicContact CB-CD2 4.1Å; P334-L375 HydrophobicContact CG-CD2 3.98Å
335	S	97.1	Very high	97.5	Very high	65 Å²	65	38.4 Å²	38.4	46%	0.455	20%	0.204	S	C	.	.	H	α-helix	trans	-61	-31.9	177.4	77.4	0	0	0	0	113.7	E333	E333-S335 PolarHBondContact O-N 3.47Å; E333-S335 PolarHBondContact OE2-OG 3.02Å
336	Q	97.5	Very high	97.4	Very high	17 Å²	17	43.1 Å²	43.1	8%	0.079	23%	0.225	C	C	.	.	H	α-helix	trans	-87.2	-37	177.4	-55.6	-57.3	-38.3	0	0	110.9	P296 I332 E333 P334 V338 K339	P296-Q336 HydrophobicContact CB-CG 4.4Å; P296-Q336 WeakPolarHBondContact O-CG 3.46Å; I332-Q336 HydrophobicContact CD1-CB 4.36Å; I332-Q336 HydrophobicContact CG1-CB 4Å; E333-Q336 HydrophobicContact CB-CG 4.28Å; E333-Q336 PolarHBondContact O-N 3.23Å; P334-Q336 VanDerWaalsContact C-N 3.27Å; P334-Q336 PolarHBondContact O-N 2.93Å; Q336-V338 VanDerWaalsContact C-N 3.32Å; Q336-V338 PolarHBondContact O-N 3.44Å; Q336-K339 WeakPolarHBondContact O-CB 3.49Å; Q336-K339 PolarHBondContact O-N 3.39Å; Q336-K339 VanDerWaalsContact O-N 3.08Å
337	F	98	Very high	97.4	Very high	0 Å²	0	42.7 Å²	42.7	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-55.1	-45.9	177.7	178.8	-101.8	0	0	0	112.2	L329 I332 E333 P334 K339 I340 Q341 L344 F345 L375 N379 I383	L329-F337 HydrophobicContact CD2-CD2 3.96Å; L329-F337 HydrophobicContact CD2-CE2 4.06Å; I332-F337 HydrophobicContact CD1-CB 3.94Å; I332-F337 HydrophobicContact CD1-CD2 4.32Å; I332-F337 HydrophobicContact CG1-CB 4.26Å; I332-F337 HydrophobicContact CG2-CB 4.28Å; I332-F337 HydrophobicContact CG2-CD2 4.39Å; E333-F337 PolarHBondContact O-N 3.39Å; P334-F337 PolarHBondContact O-N 2.92Å; F337-K339 PolarHBondContact O-N 2.8Å; F337-I340 HydrophobicContact CD2-CD1 4.07Å; F337-I340 PolarHBondContact O-N 2.75Å; F337-Q341 HydrophobicContact CD1-CB 4.31Å; F337-Q341 HydrophobicContact CE1-CB 3.96Å; F337-Q341 HydrophobicContact CZ-CB 4.14Å; F337-Q341 PolarHBondContact O-N 3.33Å; F337-L344 HydrophobicContact CE2-CD2 4.39Å; F337-F345 AromaticContact CE2-CE2 3.84Å; F337-F345 HydrophobicContact CE2-CE2 3.84Å; F337-F345 AromaticContact CZ-CE2 3.57Å; F337-F345 HydrophobicContact CZ-CE2 3.57Å; F337-F345 HydrophobicContact CZ-CZ 4.24Å; F337-L375 HydrophobicContact CB-CD2 4.46Å; F337-L375 HydrophobicContact CD1-CB 4.15Å; F337-L375 HydrophobicContact CD1-CD2 4.32Å; F337-L375 HydrophobicContact CD2-CD1 4Å; F337-L375 HydrophobicContact CE1-CB 3.87Å; F337-L375 HydrophobicContact CE2-CB 4.26Å; F337-L375 HydrophobicContact CE2-CD1 4.27Å; F337-L375 HydrophobicContact CG-CB 4.46Å; F337-L375 HydrophobicContact CG-CD1 4.2Å; F337-L375 HydrophobicContact CG-CD2 4.34Å; F337-L375 HydrophobicContact CZ-CB 3.9Å; F337-N379 HydrophobicContact CE1-CB 4.21Å; F337-I383 HydrophobicContact CE1-CD1 3.88Å; F337-I383 HydrophobicContact CZ-CD1 3.75Å
338	V	97.8	Very high	97.4	Very high	77 Å²	77	38.3 Å²	38.3	47%	0.467	20%	0.202	S	C	.	.	H	α-helix	trans	-56.4	-28.6	179.2	172.9	0	0	0	0	112.9	P334 Q336 Q341	P334-V338 WeakPolarHBondContact O-CG2 3.46Å; P334-V338 PolarHBondContact O-N 2.89Å; Q336-V338 VanDerWaalsContact C-N 3.32Å; Q336-V338 PolarHBondContact O-N 3.44Å; V338-Q341 WeakPolarHBondContact O-CG 3.45Å; V338-Q341 PolarHBondContact O-NE2 2.9Å
339	K	97.1	Very high	97.4	Very high	94 Å²	94	38.5 Å²	38.5	41%	0.409	20%	0.204	S	C	.	.	H	α-helix	trans	-76.3	-23.3	179.9	-55.4	177.8	-171.9	167.7	0	113.4	E300 R304 Q336 F337	E300-K339 WeakPolarHBondContact OE2-CD 3.2Å; R304-K339 PolarHBondContact NH2-O 2.86Å; Q336-K339 WeakPolarHBondContact O-CB 3.49Å; Q336-K339 PolarHBondContact O-N 3.39Å; Q336-K339 VanDerWaalsContact O-N 3.08Å; F337-K339 PolarHBondContact O-N 2.8Å
340	I	96.8	Very high	97.3	Very high	1 Å²	1	44.8 Å²	44.8	1%	0.005	23%	0.232	C	C	.	.	H	α-helix	trans	-119.4	-9.8	-172.4	59.3	72.3	0	0	0	114.1	E300 I303 I332 F337 E342 P343 L344	E300-I340 HydrophobicContact CB-CG2 4.11Å; E300-I340 HydrophobicContact CG-CG2 3.9Å; I303-I340 HydrophobicContact CB-CG2 4.4Å; I303-I340 HydrophobicContact CG2-CB 4.14Å; I303-I340 HydrophobicContact CG2-CG1 4.43Å; I303-I340 HydrophobicContact CG2-CG2 4.34Å; I332-I340 HydrophobicContact CD1-CD1 4.09Å; I332-I340 HydrophobicContact CD1-CG1 4.18Å; F337-I340 HydrophobicContact CD2-CD1 4.07Å; F337-I340 PolarHBondContact O-N 2.75Å; I340-E342 VanDerWaalsContact C-N 3.32Å; I340-E342 PolarHBondContact O-N 3.28Å; I340-P343 WeakPolarHBondContact O-CD 3.46Å; I340-P343 VanDerWaalsContact O-CG 3.23Å; I340-P343 WeakPolarHBondContact O-CG 3.3Å; I340-L344 HydrophobicContact CD1-CB 4.15Å; I340-L344 HydrophobicContact CD1-CD2 3.65Å; I340-L344 WeakPolarHBondContact O-CB 3.45Å; I340-L344 PolarHBondContact O-N 2.94Å
341	Q	97.6	Very high	97.3	Very high	11 Å²	11	41.2 Å²	41.2	5%	0.051	21%	0.212	C	C	.	.	H	α-helix	trans	-54.4	-44.5	-175.4	59.2	176.1	-37.5	0	0	113.1	F337 V338 L344 F345 N379 V382	F337-Q341 HydrophobicContact CD1-CB 4.31Å; F337-Q341 HydrophobicContact CE1-CB 3.96Å; F337-Q341 HydrophobicContact CZ-CB 4.14Å; F337-Q341 PolarHBondContact O-N 3.33Å; V338-Q341 WeakPolarHBondContact O-CG 3.45Å; V338-Q341 PolarHBondContact O-NE2 2.9Å; Q341-L344 PolarHBondContact O-N 3.02Å; Q341-F345 HydrophobicContact CB-CD2 4.46Å; Q341-F345 WeakPolarHBondContact O-CB 3.43Å; Q341-F345 VanDerWaalsContact O-CD2 3.29Å; Q341-F345 WeakPolarHBondContact O-CD2 3.33Å; Q341-F345 PolarHBondContact O-N 2.98Å; Q341-N379 PolarHBondContact NE2-OD1 3.42Å; Q341-V382 HydrophobicContact CG-CG1 4.37Å
342	E	97.7	Very high	97.3	Very high	98 Å²	98	38.6 Å²	38.6	46%	0.458	20%	0.197	S	C	.	.	H	α-helix	trans	-62.3	-56.9	-178.7	-81.7	-165.6	-121.3	0	0	113.3	I340 L344 K346 V382 I386	I340-E342 VanDerWaalsContact C-N 3.32Å; I340-E342 PolarHBondContact O-N 3.28Å; E342-L344 VanDerWaalsContact C-N 3.34Å; E342-K346 WeakPolarHBondContact O-CB 3.37Å; E342-K346 WeakPolarHBondContact O-CD 3.47Å; E342-K346 VanDerWaalsContact O-CG 3.23Å; E342-K346 WeakPolarHBondContact O-CG 3.31Å; E342-K346 PolarHBondContact O-N 3.39Å; E342-K346 VanDerWaalsContact O-N 3.08Å; E342-K346 IonicContact OE2-NZ 3.17Å; E342-K346 PolarHBondContact OE2-NZ 3.49Å; E342-K346 VanDerWaalsContact OE2-NZ 3.09Å; E342-V382 HydrophobicContact CG-CG1 3.63Å; E342-I386 HydrophobicContact CB-CD1 4.42Å; E342-I386 HydrophobicContact CG-CD1 4.17Å
343	P	96.8	Very high	97.2	Very high	37 Å²	37	39.5 Å²	39.5	24%	0.24	20%	0.203	C	C	.	.	H	α-helix	trans	-62.2	-43.7	177.5	22.8	-32.1	0	0	0	111.1	M307 I340 F345 K346 Q347	M307-P343 HydrophobicContact CE-CB 3.92Å; M307-P343 WeakPolarHBondContact CE-O 3.37Å; M307-P343 HydrophobicContact SD-CB 3.93Å; I340-P343 WeakPolarHBondContact O-CD 3.46Å; I340-P343 VanDerWaalsContact O-CG 3.23Å; I340-P343 WeakPolarHBondContact O-CG 3.3Å; P343-F345 PolarHBondContact O-N 3.49Å; P343-K346 WeakPolarHBondContact O-CB 3.37Å; P343-K346 PolarHBondContact O-N 3.31Å; P343-Q347 PolarHBondContact O-N 2.92Å; P343-Q347 VanDerWaalsContact O-N 3.11Å
344	L	97.5	Very high	97.1	Very high	1 Å²	1	36 Å²	36	1%	0.005	19%	0.189	C	C	.	.	H	α-helix	trans	-54.2	-56.2	179.7	176	63.9	0	0	0	111.4	L325 L329 F337 I340 Q341 E342 K346 Q347 I348	L325-L344 HydrophobicContact CD1-CD1 3.91Å; L325-L344 HydrophobicContact CD2-CD1 4.37Å; L329-L344 HydrophobicContact CD1-CD2 4.05Å; L329-L344 HydrophobicContact CD2-CD2 3.75Å; L329-L344 HydrophobicContact CG-CD2 4.41Å; F337-L344 HydrophobicContact CE2-CD2 4.39Å; I340-L344 HydrophobicContact CD1-CB 4.15Å; I340-L344 HydrophobicContact CD1-CD2 3.65Å; I340-L344 WeakPolarHBondContact O-CB 3.45Å; I340-L344 PolarHBondContact O-N 2.94Å; Q341-L344 PolarHBondContact O-N 3.02Å; E342-L344 VanDerWaalsContact C-N 3.34Å; L344-K346 VanDerWaalsContact C-N 3.31Å; L344-K346 PolarHBondContact O-N 3.4Å; L344-Q347 WeakPolarHBondContact O-CA 3.4Å; L344-Q347 WeakPolarHBondContact O-CB 3.3Å; L344-Q347 PolarHBondContact O-N 3.3Å; L344-I348 HydrophobicContact CD1-CG1 4.27Å; L344-I348 HydrophobicContact CG-CG1 4.41Å; L344-I348 WeakPolarHBondContact O-CG1 3.39Å; L344-I348 PolarHBondContact O-N 3.2Å
345	F	97.9	Very high	97	Very high	1 Å²	1	38 Å²	38	0%	0.004	20%	0.201	C	C	.	.	H	α-helix	trans	-70.8	-25	-177.5	-79.5	-88.8	0	0	0	113	F337 Q341 P343 Q347 I348 A349 I376 I383 I386 M387	F337-F345 AromaticContact CE2-CE2 3.84Å; F337-F345 HydrophobicContact CE2-CE2 3.84Å; F337-F345 AromaticContact CZ-CE2 3.57Å; F337-F345 HydrophobicContact CZ-CE2 3.57Å; F337-F345 HydrophobicContact CZ-CZ 4.24Å; Q341-F345 HydrophobicContact CB-CD2 4.46Å; Q341-F345 WeakPolarHBondContact O-CB 3.43Å; Q341-F345 VanDerWaalsContact O-CD2 3.29Å; Q341-F345 WeakPolarHBondContact O-CD2 3.33Å; Q341-F345 PolarHBondContact O-N 2.98Å; P343-F345 PolarHBondContact O-N 3.49Å; F345-Q347 PolarHBondContact O-N 3.15Å; F345-I348 PolarHBondContact O-N 2.82Å; F345-A349 WeakPolarHBondContact O-CB 3.41Å; F345-A349 PolarHBondContact O-N 3Å; F345-I376 HydrophobicContact CE1-CD1 3.89Å; F345-I376 HydrophobicContact CE1-CG1 4Å; F345-I376 HydrophobicContact CZ-CD1 3.83Å; F345-I376 HydrophobicContact CZ-CG1 3.58Å; F345-I383 HydrophobicContact CD1-CG2 3.51Å; F345-I383 HydrophobicContact CD2-CD1 4.05Å; F345-I383 HydrophobicContact CD2-CG1 3.89Å; F345-I383 HydrophobicContact CD2-CG2 4.27Å; F345-I383 HydrophobicContact CE1-CG2 3.66Å; F345-I383 HydrophobicContact CE2-CD1 3.73Å; F345-I383 HydrophobicContact CE2-CG1 4.09Å; F345-I383 HydrophobicContact CE2-CG2 4.42Å; F345-I383 HydrophobicContact CG-CG1 4.18Å; F345-I383 HydrophobicContact CG-CG2 3.83Å; F345-I383 HydrophobicContact CZ-CD1 4.03Å; F345-I383 HydrophobicContact CZ-CG2 4.13Å; F345-I386 HydrophobicContact CB-CG2 4.15Å; F345-M387 HydrophobicContact CB-CG 4.45Å; F345-M387 HydrophobicContact CB-SD 4.26Å; F345-M387 HydrophobicContact CD1-CG 3.78Å; F345-M387 HydrophobicContact CD1-SD 3.82Å
346	K	97.5	Very high	97	Very high	101 Å²	101	37.9 Å²	37.9	44%	0.439	19%	0.194	S	C	.	.	H	α-helix	trans	-62.8	-32	167.2	-76	167.1	-174.1	157.8	0	111.9	E342 P343 L344 K350 I386	E342-K346 WeakPolarHBondContact O-CB 3.37Å; E342-K346 WeakPolarHBondContact O-CD 3.47Å; E342-K346 VanDerWaalsContact O-CG 3.23Å; E342-K346 WeakPolarHBondContact O-CG 3.31Å; E342-K346 PolarHBondContact O-N 3.39Å; E342-K346 VanDerWaalsContact O-N 3.08Å; E342-K346 IonicContact OE2-NZ 3.17Å; E342-K346 PolarHBondContact OE2-NZ 3.49Å; E342-K346 VanDerWaalsContact OE2-NZ 3.09Å; P343-K346 WeakPolarHBondContact O-CB 3.37Å; P343-K346 PolarHBondContact O-N 3.31Å; L344-K346 VanDerWaalsContact C-N 3.31Å; L344-K346 PolarHBondContact O-N 3.4Å; K346-K350 WeakPolarHBondContact O-CG 3.22Å; K346-I386 HydrophobicContact CB-CG2 4.42Å; K346-I386 HydrophobicContact CG-CG2 3.76Å
347	Q	97.7	Very high	96.9	Very high	24 Å²	24	40.9 Å²	40.9	11%	0.112	21%	0.206	C	C	.	.	H	α-helix	trans	-79.5	-44.9	174.8	-172.5	55.3	41.5	0	0	111.7	M307 W310 P343 L344 F345 A349 K350 C351	M307-Q347 HydrophobicContact CE-CB 3.53Å; M307-Q347 HydrophobicContact CE-CG 4.32Å; W310-Q347 VanDerWaalsContact CD1-NE2 3.32Å; W310-Q347 HydrophobicContact CD2-CG 3.85Å; W310-Q347 VanDerWaalsContact CE2-NE2 3.35Å; W310-Q347 HydrophobicContact CE3-CG 4.09Å; W310-Q347 HydrophobicContact CG-CG 4.38Å; W310-Q347 HydrophobicContact CH2-CG 4.38Å; W310-Q347 HydrophobicContact CZ2-CG 4.16Å; W310-Q347 HydrophobicContact CZ3-CG 4.35Å; P343-Q347 PolarHBondContact O-N 2.92Å; P343-Q347 VanDerWaalsContact O-N 3.11Å; L344-Q347 WeakPolarHBondContact O-CA 3.4Å; L344-Q347 WeakPolarHBondContact O-CB 3.3Å; L344-Q347 PolarHBondContact O-N 3.3Å; F345-Q347 PolarHBondContact O-N 3.15Å; Q347-A349 VanDerWaalsContact C-N 3.28Å; Q347-A349 PolarHBondContact O-N 3.06Å; Q347-K350 WeakPolarHBondContact O-CB 3.19Å; Q347-K350 PolarHBondContact O-N 3.4Å; Q347-C351 PolarHBondContact O-N 3.26Å; Q347-C351 VanDerWaalsContact O-N 3.09Å; Q347-C351 PolarHBondContact O-SG 2.91Å
348	I	97.5	Very high	96.9	Very high	1 Å²	1	45.4 Å²	45.4	1%	0.005	23%	0.228	C	C	.	.	H	α-helix	trans	-58	-40.6	175.1	-60.3	-58.2	0	0	0	111.2	L322 L344 F345 K350 C351 V352 Y366 W367 M387	L322-I348 HydrophobicContact CD2-CD1 3.65Å; L344-I348 HydrophobicContact CD1-CG1 4.27Å; L344-I348 HydrophobicContact CG-CG1 4.41Å; L344-I348 WeakPolarHBondContact O-CG1 3.39Å; L344-I348 PolarHBondContact O-N 3.2Å; F345-I348 PolarHBondContact O-N 2.82Å; I348-K350 PolarHBondContact O-N 3.2Å; I348-C351 WeakPolarHBondContact O-CB 3.44Å; I348-C351 PolarHBondContact O-N 3.25Å; I348-V352 HydrophobicContact CG2-CG2 4.2Å; I348-V352 WeakPolarHBondContact O-CG2 3.19Å; I348-V352 PolarHBondContact O-N 2.97Å; I348-Y366 HydrophobicContact CD1-CD2 4.31Å; I348-Y366 HydrophobicContact CD1-CE2 3.67Å; I348-Y366 HydrophobicContact CG1-CE2 4.34Å; I348-W367 HydrophobicContact CG2-CH2 4.16Å; I348-W367 HydrophobicContact CG2-CZ3 4.29Å; I348-M387 HydrophobicContact CB-SD 4.39Å; I348-M387 HydrophobicContact CG2-CE 4.19Å; I348-M387 HydrophobicContact CG2-SD 4.28Å
349	A	97.5	Very high	96.9	Very high	5 Å²	5	41.8 Å²	41.8	4%	0.041	21%	0.205	C	C	.	.	H	α-helix	trans	-55.9	-37.7	174.8	0	0	0	0	0	113.2	F345 Q347 S353 M387 S390	F345-A349 WeakPolarHBondContact O-CB 3.41Å; F345-A349 PolarHBondContact O-N 3Å; Q347-A349 VanDerWaalsContact C-N 3.28Å; Q347-A349 PolarHBondContact O-N 3.06Å; A349-S353 WeakPolarHBondContact O-CB 3.41Å; A349-S353 PolarHBondContact O-N 2.89Å; A349-S353 VanDerWaalsContact O-N 3.13Å; A349-S353 PolarHBondContact O-OG 3.17Å; A349-M387 HydrophobicContact CB-CE 4.19Å; A349-M387 HydrophobicContact CB-SD 3.68Å; A349-S390 WeakPolarHBondContact O-CB 3.29Å; A349-S390 PolarHBondContact O-OG 3.45Å
350	K	96.6	Very high	96.9	Very high	132 Å²	132	37.3 Å²	37.3	57%	0.574	19%	0.186	S	C	*	.	H	α-helix	trans	-70.5	-41	174.5	-65.3	172.9	-172.4	170.7	0	111.8	K346 Q347 I348 S353 S354	K346-K350 WeakPolarHBondContact O-CG 3.22Å; Q347-K350 WeakPolarHBondContact O-CB 3.19Å; Q347-K350 PolarHBondContact O-N 3.4Å; I348-K350 PolarHBondContact O-N 3.2Å; K350-S353 CarbonylContact O-C 3.35Å; K350-S353 WeakPolarHBondContact O-CA 3.22Å; K350-S353 WeakPolarHBondContact O-CB 3.42Å; K350-S353 PolarHBondContact O-N 2.95Å; K350-S353 VanDerWaalsContact O-N 3.11Å; K350-S354 PolarHBondContact O-N 3.43Å
351	C	97.2	Very high	96.9	Very high	0 Å²	0	40 Å²	40	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-65	-44.4	179.9	-56.8	0	0	0	0	111.2	W310 L322 Q347 I348 S353 S354 V359 A360 A363	W310-C351 WeakPolarHBondContact CZ2-SG 3.38Å; L322-C351 HydrophobicContact CD1-CB 4.23Å; L322-C351 HydrophobicContact CD2-CB 4.22Å; Q347-C351 PolarHBondContact O-N 3.26Å; Q347-C351 VanDerWaalsContact O-N 3.09Å; Q347-C351 PolarHBondContact O-SG 2.91Å; I348-C351 WeakPolarHBondContact O-CB 3.44Å; I348-C351 PolarHBondContact O-N 3.25Å; C351-S353 PolarHBondContact O-N 3.22Å; C351-S354 WeakPolarHBondContact O-CB 3.27Å; C351-S354 PolarHBondContact O-N 3.25Å; C351-V359 HydrophobicContact CB-CG1 4.05Å; C351-A360 WeakPolarHBondContact O-CA 3.44Å; C351-A363 HydrophobicContact CB-CB 3.75Å
352	V	96.3	Very high	96.9	Very high	0 Å²	0	42.1 Å²	42.1	0%	0	21%	0.206	C	C	.	.	H	α-helix	trans	-61	-33.2	171.8	171.9	0	0	0	0	111.6	I348 S354 A363 L364 W367 M387 L391 V407	I348-V352 HydrophobicContact CG2-CG2 4.2Å; I348-V352 WeakPolarHBondContact O-CG2 3.19Å; I348-V352 PolarHBondContact O-N 2.97Å; V352-S354 VanDerWaalsContact C-N 3.25Å; V352-S354 PolarHBondContact O-N 3.41Å; V352-A363 HydrophobicContact CG2-CB 3.85Å; V352-L364 HydrophobicContact CG1-CD2 3.81Å; V352-L364 HydrophobicContact CG1-CG 4.21Å; V352-L364 HydrophobicContact CG2-CD2 4.04Å; V352-L364 HydrophobicContact CG2-CG 4.14Å; V352-W367 HydrophobicContact CG2-CZ3 4.34Å; V352-M387 HydrophobicContact CB-CE 4.49Å; V352-M387 HydrophobicContact CG2-CE 4.11Å; V352-L391 HydrophobicContact CG1-CD2 3.69Å; V352-L391 HydrophobicContact CG1-CG 4.39Å; V352-V407 HydrophobicContact CG1-CG2 4.45Å
353	S	95.2	Very high	96.9	Very high	20 Å²	20	37.4 Å²	37.4	14%	0.14	18%	0.184	C	C	.	.	T	Hydrogen-bonded Turn	trans	-80.5	0.8	174.1	-63.3	0	0	0	0	114.9	A349 K350 C351 S390 R393	A349-S353 WeakPolarHBondContact O-CB 3.41Å; A349-S353 PolarHBondContact O-N 2.89Å; A349-S353 VanDerWaalsContact O-N 3.13Å; A349-S353 PolarHBondContact O-OG 3.17Å; K350-S353 CarbonylContact O-C 3.35Å; K350-S353 WeakPolarHBondContact O-CA 3.22Å; K350-S353 WeakPolarHBondContact O-CB 3.42Å; K350-S353 PolarHBondContact O-N 2.95Å; K350-S353 VanDerWaalsContact O-N 3.11Å; C351-S353 PolarHBondContact O-N 3.22Å; S353-S390 VanDerWaalsContact OG-CB 3.23Å; S353-S390 WeakPolarHBondContact OG-CB 3.45Å; S353-S390 PolarHBondContact OG-OG 3.44Å; S353-R393 VanDerWaalsContact CB-NH2 3.3Å; S353-R393 PolarHBondContact OG-NH2 3Å
354	S	95.3	Very high	97	Very high	16 Å²	16	35.8 Å²	35.8	11%	0.112	17%	0.174	C	C	.	.			trans	-66.9	136.2	-177.6	-174.4	0	0	0	0	110.3	K350 C351 V352 H356 H398	K350-S354 PolarHBondContact O-N 3.43Å; C351-S354 WeakPolarHBondContact O-CB 3.27Å; C351-S354 PolarHBondContact O-N 3.25Å; V352-S354 VanDerWaalsContact C-N 3.25Å; V352-S354 PolarHBondContact O-N 3.41Å; S354-H356 PolarHBondContact O-N 3.25Å; S354-H356 PolarHBondContact OG-N 3.32Å; S354-H398 PolarHBondContact O-NE2 3.11Å
355	P	94.6	Very high	96.9	Very high	97 Å²	97	39.9 Å²	39.9	63%	0.63	19%	0.19	S	C	*	.	S	Bend	trans	-70.7	-13.6	171.5	30.9	-35.5	0	0	0	112.5	F357 W399	P355-F357 PolarHBondContact O-N 3.01Å; P355-W399 PolarHBondContact O-NE1 3.14Å
356	H	96.3	Very high	96.9	Very high	63 Å²	63	40 Å²	40	29%	0.292	19%	0.19	S	C	.	.	S	Bend	trans	-81.9	110.3	178.1	-167	-71.9	0	0	0	110.1	S315 S354 Q358 V359 A360	S315-H356 PolarHBondContact OG-CD2 2.94Å; S354-H356 PolarHBondContact O-N 3.25Å; S354-H356 PolarHBondContact OG-N 3.32Å; H356-Q358 VanDerWaalsContact C-N 3.33Å; H356-Q358 PolarHBondContact CE1-OE1 3.39Å; H356-Q358 PolarHBondContact ND1-N 2.92Å; H356-Q358 PolarHBondContact O-N 3.44Å; H356-V359 HydrophobicContact CB-CB 4.33Å; H356-V359 HydrophobicContact CB-CG2 4.15Å; H356-V359 PolarHBondContact O-N 3Å; H356-A360 PolarHBondContact O-N 3.15Å; H356-A360 VanDerWaalsContact O-N 3.13Å
357	F	96.2	Very high	96.8	Very high	79 Å²	79	36.1 Å²	36.1	35%	0.346	17%	0.172	S	C	.	.	H	α-helix	trans	-58.9	-39.8	-168.5	81.5	-84.5	0	0	0	113.3	P355 V359 A360 E361 W399 I403	P355-F357 PolarHBondContact O-N 3.01Å; F357-V359 VanDerWaalsContact C-N 3.28Å; F357-V359 PolarHBondContact O-N 3.32Å; F357-A360 PolarHBondContact O-N 3.01Å; F357-E361 WeakPolarHBondContact O-CB 3.05Å; F357-E361 PolarHBondContact O-N 3.46Å; F357-W399 HydrophobicContact CB-CZ2 4.27Å; F357-I403 HydrophobicContact CB-CD1 4.37Å; F357-I403 HydrophobicContact CB-CG1 4.25Å
358	Q	97.4	Very high	96.7	Very high	96 Å²	96	40.6 Å²	40.6	45%	0.449	20%	0.197	S	C	.	.	H	α-helix	trans	-64.2	-32.3	179.4	-60.3	-179.3	-77	0	0	112.7	V319 H356 R362	V319-Q358 HydrophobicContact CG2-CB 4.05Å; H356-Q358 VanDerWaalsContact C-N 3.33Å; H356-Q358 PolarHBondContact CE1-OE1 3.39Å; H356-Q358 PolarHBondContact ND1-N 2.92Å; H356-Q358 PolarHBondContact O-N 3.44Å; Q358-R362 WeakPolarHBondContact O-CB 3.14Å; Q358-R362 PolarHBondContact O-N 3.47Å
359	V	98	Very high	96.7	Very high	0 Å²	0	41.6 Å²	41.6	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-73.1	-47.8	177.9	172.8	0	0	0	0	109.7	E318 V319 L322 C351 H356 F357 R362 A363	E318-V359 HydrophobicContact CB-CG2 4.15Å; E318-V359 VanDerWaalsContact CD-CG1 3.49Å; E318-V359 HydrophobicContact CG-CG1 3.82Å; E318-V359 HydrophobicContact CG-CG2 4.12Å; V319-V359 HydrophobicContact CG2-CG2 3.95Å; L322-V359 HydrophobicContact CD1-CG1 4.07Å; C351-V359 HydrophobicContact CB-CG1 4.05Å; H356-V359 HydrophobicContact CB-CB 4.33Å; H356-V359 HydrophobicContact CB-CG2 4.15Å; H356-V359 PolarHBondContact O-N 3Å; F357-V359 VanDerWaalsContact C-N 3.28Å; F357-V359 PolarHBondContact O-N 3.32Å; V359-R362 PolarHBondContact O-N 3.31Å; V359-A363 WeakPolarHBondContact O-CB 3.21Å; V359-A363 PolarHBondContact O-N 3.28Å
360	A	97.4	Very high	96.6	Very high	0 Å²	0	49.6 Å²	49.6	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-62.6	-45.2	178.8	0	0	0	0	0	111.7	C351 H356 F357 A363 L364 I403	C351-A360 WeakPolarHBondContact O-CA 3.44Å; H356-A360 PolarHBondContact O-N 3.15Å; H356-A360 VanDerWaalsContact O-N 3.13Å; F357-A360 PolarHBondContact O-N 3.01Å; A360-A363 PolarHBondContact O-N 3.26Å; A360-L364 WeakPolarHBondContact O-CB 3.46Å; A360-L364 WeakPolarHBondContact O-CD1 3.45Å; A360-L364 WeakPolarHBondContact O-CG 3.45Å; A360-L364 PolarHBondContact O-N 3.2Å; A360-I403 HydrophobicContact CB-CD1 4.2Å; A360-I403 HydrophobicContact CB-CG2 3.99Å
361	E	97.4	Very high	96.7	Very high	58 Å²	58	47.2 Å²	47.2	27%	0.271	23%	0.227	S	C	.	.	H	α-helix	trans	-58.8	-52.3	176	-178.9	177.9	-128.5	0	0	111.2	F357 A363 L364 Y365 I403 L406	F357-E361 WeakPolarHBondContact O-CB 3.05Å; F357-E361 PolarHBondContact O-N 3.46Å; E361-A363 VanDerWaalsContact C-N 3.27Å; E361-A363 PolarHBondContact O-N 3.38Å; E361-L364 PolarHBondContact O-N 2.81Å; E361-L364 VanDerWaalsContact O-N 3.08Å; E361-Y365 HydrophobicContact CG-CD2 4.26Å; E361-Y365 HydrophobicContact CG-CE1 4.32Å; E361-Y365 HydrophobicContact CG-CE2 3.61Å; E361-Y365 PolarHBondContact O-N 3.21Å; E361-Y365 PolarHBondContact OE1-OH 3.47Å; E361-Y365 VanDerWaalsContact OE1-OH 3.07Å; E361-I403 HydrophobicContact CB-CD1 3.73Å; E361-L406 HydrophobicContact CG-CD1 4.09Å
362	R	97.9	Very high	96.7	Very high	55 Å²	55	47.2 Å²	47.2	21%	0.208	23%	0.227	C	C	.	.	H	α-helix	trans	-59.1	-38.6	-178.9	-175.3	68.2	-171.5	90.7	-15.7	112.6	V319 L322 E326 Q358 V359	V319-R362 HydrophobicContact CG1-CB 4.32Å; V319-R362 HydrophobicContact CG1-CG 4.09Å; L322-R362 HydrophobicContact CB-CG 3.67Å; L322-R362 HydrophobicContact CD1-CB 4.13Å; L322-R362 HydrophobicContact CD1-CG 4.17Å; E326-R362 IonicContact OE2-CZ 2.74Å; E326-R362 IonicContact OE2-NH1 3.37Å; E326-R362 PolarHBondContact OE2-NH1 2.95Å; E326-R362 IonicContact OE2-NH2 3.12Å; E326-R362 PolarHBondContact OE2-NH2 3.23Å; Q358-R362 WeakPolarHBondContact O-CB 3.14Å; Q358-R362 PolarHBondContact O-N 3.47Å; V359-R362 PolarHBondContact O-N 3.31Å
363	A	97.9	Very high	96.7	Very high	0 Å²	0	49.4 Å²	49.4	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-70.8	-37.3	176.4	0	0	0	0	0	112.5	L322 C351 V352 V359 A360 E361 Y365 Y366 W367	L322-A363 HydrophobicContact CD1-CB 4.04Å; L322-A363 HydrophobicContact CD2-CB 4.15Å; C351-A363 HydrophobicContact CB-CB 3.75Å; V352-A363 HydrophobicContact CG2-CB 3.85Å; V359-A363 WeakPolarHBondContact O-CB 3.21Å; V359-A363 PolarHBondContact O-N 3.28Å; A360-A363 PolarHBondContact O-N 3.26Å; E361-A363 VanDerWaalsContact C-N 3.27Å; E361-A363 PolarHBondContact O-N 3.38Å; A363-Y365 VanDerWaalsContact C-N 3.29Å; A363-Y365 PolarHBondContact O-N 2.87Å; A363-Y366 WeakPolarHBondContact O-CB 3.37Å; A363-Y366 PolarHBondContact O-N 2.91Å; A363-W367 WeakPolarHBondContact O-CZ3 3.47Å
364	L	97.2	Very high	96.8	Very high	3 Å²	3	50.4 Å²	50.4	2%	0.016	25%	0.245	C	C	.	.	H	α-helix	trans	-70.3	-24.5	178.2	-74.1	163.9	0	0	0	112.9	V352 A360 E361 Y366 W367 L391 I403 L406 V407 V410	V352-L364 HydrophobicContact CG1-CD2 3.81Å; V352-L364 HydrophobicContact CG1-CG 4.21Å; V352-L364 HydrophobicContact CG2-CD2 4.04Å; V352-L364 HydrophobicContact CG2-CG 4.14Å; A360-L364 WeakPolarHBondContact O-CB 3.46Å; A360-L364 WeakPolarHBondContact O-CD1 3.45Å; A360-L364 WeakPolarHBondContact O-CG 3.45Å; A360-L364 PolarHBondContact O-N 3.2Å; E361-L364 PolarHBondContact O-N 2.81Å; E361-L364 VanDerWaalsContact O-N 3.08Å; L364-Y366 PolarHBondContact O-N 3.26Å; L364-W367 PolarHBondContact O-N 3.18Å; L364-L391 HydrophobicContact CD2-CD2 3.93Å; L364-I403 HydrophobicContact CD1-CG2 3.91Å; L364-L406 HydrophobicContact CB-CB 4.27Å; L364-L406 HydrophobicContact CB-CD1 4.44Å; L364-L406 HydrophobicContact CD1-CB 3.82Å; L364-L406 HydrophobicContact CD1-CD1 4.43Å; L364-V407 HydrophobicContact CD1-CG2 3.67Å; L364-V407 HydrophobicContact CD2-CG2 3.88Å; L364-V407 HydrophobicContact CG-CG2 4.44Å; L364-V410 HydrophobicContact CD2-CB 4.41Å; L364-V410 HydrophobicContact CD2-CG2 3.83Å
365	Y	96.5	Very high	96.9	Very high	87 Å²	87	49.7 Å²	49.7	34%	0.341	24%	0.24	S	C	.	.	G	3₁₀ helix	trans	-67.7	-11.4	174.8	-73.2	-23.2	0	0	0	115	E361 A363 W367 N368 L406	E361-Y365 HydrophobicContact CG-CD2 4.26Å; E361-Y365 HydrophobicContact CG-CE1 4.32Å; E361-Y365 HydrophobicContact CG-CE2 3.61Å; E361-Y365 PolarHBondContact O-N 3.21Å; E361-Y365 PolarHBondContact OE1-OH 3.47Å; E361-Y365 VanDerWaalsContact OE1-OH 3.07Å; A363-Y365 VanDerWaalsContact C-N 3.29Å; A363-Y365 PolarHBondContact O-N 2.87Å; Y365-W367 PolarHBondContact O-N 3.35Å; Y365-W367 VanDerWaalsContact O-N 3.16Å; Y365-N368 VanDerWaalsContact CD1-ND2 3.34Å; Y365-N368 WeakPolarHBondContact CD1-ND2 3.48Å; Y365-N368 WeakPolarHBondContact O-CB 3.48Å; Y365-N368 PolarHBondContact O-N 3.37Å; Y365-L406 HydrophobicContact CE1-CD1 4.15Å; Y365-L406 HydrophobicContact CE1-CD2 4.04Å
366	Y	97.3	Very high	97	Very high	2 Å²	2	45.1 Å²	45.1	1%	0.008	21%	0.21	C	C	.	.	G	3₁₀ helix	trans	-59.3	-28.1	172.3	-79.4	34.2	0	0	0	112.2	L322 L325 E326 L329 I348 A363 L364 N368 N369 I372	L322-Y366 WeakPolarHBondContact CA-OH 3.38Å; L322-Y366 PolarHBondContact O-OH 3.04Å; L325-Y366 WeakPolarHBondContact CB-OH 3.47Å; E326-Y366 HydrophobicContact CB-CD1 4.47Å; E326-Y366 HydrophobicContact CB-CE1 3.92Å; E326-Y366 PolarHBondContact N-OH 3.18Å; L329-Y366 HydrophobicContact CD1-CD2 4.12Å; L329-Y366 HydrophobicContact CD1-CE2 3.72Å; I348-Y366 HydrophobicContact CD1-CD2 4.31Å; I348-Y366 HydrophobicContact CD1-CE2 3.67Å; I348-Y366 HydrophobicContact CG1-CE2 4.34Å; A363-Y366 WeakPolarHBondContact O-CB 3.37Å; A363-Y366 PolarHBondContact O-N 2.91Å; L364-Y366 PolarHBondContact O-N 3.26Å; Y366-N368 PolarHBondContact O-N 3.28Å; Y366-N369 PolarHBondContact O-N 3.08Å; Y366-I372 HydrophobicContact CD2-CD1 4.27Å; Y366-I372 HydrophobicContact CG-CD1 4.42Å
367	W	96.3	Very high	96.9	Very high	20 Å²	20	48 Å²	48	8%	0.076	22%	0.223	C	C	.	.	G	3₁₀ helix	trans	-75.3	-7.7	176.6	-78.5	-97.5	0	0	0	113.9	I348 V352 A363 L364 Y365 M373 M387 V410 F414	I348-W367 HydrophobicContact CG2-CH2 4.16Å; I348-W367 HydrophobicContact CG2-CZ3 4.29Å; V352-W367 HydrophobicContact CG2-CZ3 4.34Å; A363-W367 WeakPolarHBondContact O-CZ3 3.47Å; L364-W367 PolarHBondContact O-N 3.18Å; Y365-W367 PolarHBondContact O-N 3.35Å; Y365-W367 VanDerWaalsContact O-N 3.16Å; W367-M373 HydrophobicContact CB-SD 3.95Å; W367-M373 HydrophobicContact CG-SD 3.85Å; W367-M373 WeakPolarHBondContact O-CG 3.38Å; W367-M387 HydrophobicContact CH2-CE 3.57Å; W367-M387 HydrophobicContact CH2-SD 4.43Å; W367-M387 HydrophobicContact CZ2-CE 4.18Å; W367-V410 HydrophobicContact CB-CG2 3.81Å; W367-V410 HydrophobicContact CD2-CB 4.28Å; W367-V410 HydrophobicContact CD2-CG1 3.59Å; W367-V410 HydrophobicContact CD2-CG2 3.67Å; W367-V410 HydrophobicContact CE3-CG1 4.21Å; W367-V410 HydrophobicContact CE3-CG2 3.95Å; W367-V410 HydrophobicContact CG-CB 4.26Å; W367-V410 HydrophobicContact CG-CG1 3.89Å; W367-V410 HydrophobicContact CG-CG2 3.58Å; W367-V410 HydrophobicContact CH2-CG1 4.47Å; W367-V410 HydrophobicContact CZ2-CG1 3.87Å; W367-F414 AromaticContact CE2-CE2 3.63Å; W367-F414 AromaticContact CE2-CZ 3.89Å; W367-F414 AromaticContact CZ2-CE2 3.48Å; W367-F414 HydrophobicContact CZ2-CE2 3.48Å; W367-F414 VanDerWaalsContact CZ2-CE2 3.48Å; W367-F414 AromaticContact CZ2-CZ 3.63Å; W367-F414 HydrophobicContact CZ2-CZ 3.63Å; W367-F414 AromaticContact NE1-CE2 3.35Å; W367-F414 VanDerWaalsContact NE1-CE2 3.35Å; W367-F414 AromaticContact NE1-CZ 3.54Å
368	N	95.3	Very high	96.9	Very high	118 Å²	118	50.7 Å²	50.7	63%	0.631	24%	0.237	S	C	*	.	G	3₁₀ helix	trans	-87.3	-12.4	172.5	-64.2	-15.6	0	0	0	112.2	Y365 Y366	Y365-N368 VanDerWaalsContact CD1-ND2 3.34Å; Y365-N368 WeakPolarHBondContact CD1-ND2 3.48Å; Y365-N368 WeakPolarHBondContact O-CB 3.48Å; Y365-N368 PolarHBondContact O-N 3.37Å; Y366-N368 PolarHBondContact O-N 3.28Å
369	N	96.4	Very high	96.8	Very high	22 Å²	22	47.2 Å²	47.2	12%	0.118	22%	0.222	C	C	.	.			trans	-87.5	114.9	-178.9	-174.1	-52.2	0	0	0	110	E326 D330 Y366 Y371 I372 M373	E326-N369 PolarHBondContact OE1-ND2 3.35Å; D330-N369 PolarHBondContact OD1-ND2 3.09Å; D330-N369 PolarHBondContact OD1-OD1 3.44Å; D330-N369 PolarHBondContact OD2-ND2 2.99Å; Y366-N369 PolarHBondContact O-N 3.08Å; N369-Y371 VanDerWaalsContact C-N 3.29Å; N369-Y371 PolarHBondContact O-N 3.45Å; N369-Y371 PolarHBondContact OD1-N 3.34Å; N369-I372 HydrophobicContact CB-CB 4.05Å; N369-I372 HydrophobicContact CB-CD1 3.96Å; N369-I372 HydrophobicContact CB-CG1 4.06Å; N369-I372 PolarHBondContact O-N 2.94Å; N369-I372 PolarHBondContact OD1-N 3.28Å; N369-I372 VanDerWaalsContact OD1-N 3.14Å; N369-M373 WeakPolarHBondContact O-CB 3.4Å; N369-M373 VanDerWaalsContact O-CG 3.29Å; N369-M373 WeakPolarHBondContact O-CG 3.18Å; N369-M373 PolarHBondContact O-N 3.3Å
370	E	96.6	Very high	96.7	Very high	173 Å²	173	47.9 Å²	47.9	81%	0.808	23%	0.226	S	C	*	.	H	α-helix	trans	-60.3	-37.9	-175.1	-64.6	-173.9	169.3	0	0	112.6	M373 S374	E370-M373 PolarHBondContact O-N 3.32Å; E370-S374 PolarHBondContact O-N 3.44Å
371	Y	97.9	Very high	96.5	Very high	82 Å²	82	52.8 Å²	52.8	32%	0.322	25%	0.253	S	S	.	.	H	α-helix	trans	-71.8	-46.8	-179.2	-175.2	-120	0	0	0	111.5	L329 I332 N369 M373 S374 L375	L329-Y371 WeakPolarHBondContact O-CD1 3.49Å; L329-Y371 VanDerWaalsContact O-CE1 3.27Å; L329-Y371 WeakPolarHBondContact O-CE1 3.28Å; I332-Y371 HydrophobicContact CG2-CE1 4.27Å; I332-Y371 WeakPolarHBondContact O-CE1 3.42Å; I332-Y371 PolarHBondContact O-OH 3.26Å; N369-Y371 VanDerWaalsContact C-N 3.29Å; N369-Y371 PolarHBondContact O-N 3.45Å; N369-Y371 PolarHBondContact OD1-N 3.34Å; Y371-M373 PolarHBondContact O-N 3.34Å; Y371-S374 PolarHBondContact O-N 3.32Å; Y371-S374 VanDerWaalsContact O-N 3.12Å; Y371-S374 PolarHBondContact O-OG 3.33Å; Y371-L375 HydrophobicContact CD1-CD1 4.19Å; Y371-L375 HydrophobicContact CE1-CD1 3.82Å; Y371-L375 HydrophobicContact CE1-CG 4.44Å; Y371-L375 PolarHBondContact O-N 3.13Å; Y371-L375 VanDerWaalsContact O-N 3.09Å
372	I	97.5	Very high	96.5	Very high	1 Å²	1	52.6 Å²	52.6	1%	0.005	26%	0.255	C	S	.	.	H	α-helix	trans	-58.3	-40.9	174.1	-62.8	179.5	0	0	0	110.7	E326 L329 Y366 N369 S374 L375 I376	E326-I372 HydrophobicContact CG-CD1 3.88Å; L329-I372 HydrophobicContact CB-CD1 3.81Å; L329-I372 HydrophobicContact CB-CG1 3.9Å; L329-I372 HydrophobicContact CD1-CD1 3.94Å; L329-I372 HydrophobicContact CD1-CG1 4.42Å; Y366-I372 HydrophobicContact CD2-CD1 4.27Å; Y366-I372 HydrophobicContact CG-CD1 4.42Å; N369-I372 HydrophobicContact CB-CB 4.05Å; N369-I372 HydrophobicContact CB-CD1 3.96Å; N369-I372 HydrophobicContact CB-CG1 4.06Å; N369-I372 PolarHBondContact O-N 2.94Å; N369-I372 PolarHBondContact OD1-N 3.28Å; N369-I372 VanDerWaalsContact OD1-N 3.14Å; I372-S374 PolarHBondContact O-N 2.98Å; I372-L375 PolarHBondContact O-N 3.09Å; I372-I376 HydrophobicContact CG2-CD1 3.83Å; I372-I376 HydrophobicContact CG2-CG1 4.38Å; I372-I376 VanDerWaalsContact O-CG1 3.28Å; I372-I376 WeakPolarHBondContact O-CG1 3.42Å; I372-I376 PolarHBondContact O-N 3.3Å
373	M	96	Very high	96.4	Very high	45 Å²	45	50 Å²	50	22%	0.222	25%	0.245	C	C	.	.	H	α-helix	trans	-60.9	-42.9	176	-78.7	-60.4	-61.8	0	0	112.4	W367 N369 E370 Y371 L375 I376 E377 A413	W367-M373 HydrophobicContact CB-SD 3.95Å; W367-M373 HydrophobicContact CG-SD 3.85Å; W367-M373 WeakPolarHBondContact O-CG 3.38Å; N369-M373 WeakPolarHBondContact O-CB 3.4Å; N369-M373 VanDerWaalsContact O-CG 3.29Å; N369-M373 WeakPolarHBondContact O-CG 3.18Å; N369-M373 PolarHBondContact O-N 3.3Å; E370-M373 PolarHBondContact O-N 3.32Å; Y371-M373 PolarHBondContact O-N 3.34Å; M373-L375 PolarHBondContact O-N 3.46Å; M373-I376 PolarHBondContact O-N 2.87Å; M373-I376 HydrophobicContact SD-CD1 4.35Å; M373-E377 PolarHBondContact O-N 2.97Å; M373-A413 HydrophobicContact CE-CB 4.25Å
374	S	96.8	Very high	96.3	Very high	41 Å²	41	50 Å²	50	29%	0.287	25%	0.246	S	C	.	.	H	α-helix	trans	-61.5	-42	176	75.3	0	0	0	0	112.6	E370 Y371 I372 I376 E377 E378	E370-S374 PolarHBondContact O-N 3.44Å; Y371-S374 PolarHBondContact O-N 3.32Å; Y371-S374 VanDerWaalsContact O-N 3.12Å; Y371-S374 PolarHBondContact O-OG 3.33Å; I372-S374 PolarHBondContact O-N 2.98Å; S374-I376 VanDerWaalsContact C-N 3.33Å; S374-I376 PolarHBondContact O-N 2.86Å; S374-E377 PolarHBondContact O-N 3.08Å; S374-E378 PolarHBondContact O-N 2.99Å; S374-E378 VanDerWaalsContact O-N 3.08Å
375	L	97.4	Very high	96.2	Very high	2 Å²	2	52.4 Å²	52.4	1%	0.01	26%	0.261	C	S	.	.	H	α-helix	trans	-63.2	-38.3	174.7	-67.3	173.2	0	0	0	112.3	I332 P334 F337 Y371 I372 M373 N379	I332-L375 HydrophobicContact CG2-CD1 3.64Å; P334-L375 HydrophobicContact CB-CD2 4.1Å; P334-L375 HydrophobicContact CG-CD2 3.98Å; F337-L375 HydrophobicContact CB-CD2 4.46Å; F337-L375 HydrophobicContact CD1-CB 4.15Å; F337-L375 HydrophobicContact CD1-CD2 4.32Å; F337-L375 HydrophobicContact CD2-CD1 4Å; F337-L375 HydrophobicContact CE1-CB 3.87Å; F337-L375 HydrophobicContact CE2-CB 4.26Å; F337-L375 HydrophobicContact CE2-CD1 4.27Å; F337-L375 HydrophobicContact CG-CB 4.46Å; F337-L375 HydrophobicContact CG-CD1 4.2Å; F337-L375 HydrophobicContact CG-CD2 4.34Å; F337-L375 HydrophobicContact CZ-CB 3.9Å; Y371-L375 HydrophobicContact CD1-CD1 4.19Å; Y371-L375 HydrophobicContact CE1-CD1 3.82Å; Y371-L375 HydrophobicContact CE1-CG 4.44Å; Y371-L375 PolarHBondContact O-N 3.13Å; Y371-L375 VanDerWaalsContact O-N 3.09Å; I372-L375 PolarHBondContact O-N 3.09Å; M373-L375 PolarHBondContact O-N 3.46Å; L375-N379 WeakPolarHBondContact O-CB 3.45Å; L375-N379 PolarHBondContact O-N 3.24Å; L375-N379 PolarHBondContact O-ND2 3Å
376	I	96.7	Very high	96.1	Very high	0 Å²	0	49.8 Å²	49.8	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-65.7	-39.5	175.5	-69.1	167.8	0	0	0	110.9	F345 I372 M373 S374 N379 S380 I383 F414 M417	F345-I376 HydrophobicContact CE1-CD1 3.89Å; F345-I376 HydrophobicContact CE1-CG1 4Å; F345-I376 HydrophobicContact CZ-CD1 3.83Å; F345-I376 HydrophobicContact CZ-CG1 3.58Å; I372-I376 HydrophobicContact CG2-CD1 3.83Å; I372-I376 HydrophobicContact CG2-CG1 4.38Å; I372-I376 VanDerWaalsContact O-CG1 3.28Å; I372-I376 WeakPolarHBondContact O-CG1 3.42Å; I372-I376 PolarHBondContact O-N 3.3Å; M373-I376 PolarHBondContact O-N 2.87Å; M373-I376 HydrophobicContact SD-CD1 4.35Å; S374-I376 VanDerWaalsContact C-N 3.33Å; S374-I376 PolarHBondContact O-N 2.86Å; I376-N379 CarbonylContact O-C 3.54Å; I376-N379 PolarHBondContact O-N 3.19Å; I376-S380 WeakPolarHBondContact O-CA 3.4Å; I376-S380 PolarHBondContact O-N 3.03Å; I376-I383 HydrophobicContact CB-CD1 4.39Å; I376-I383 HydrophobicContact CG1-CD1 4.14Å; I376-I383 HydrophobicContact CG2-CG2 4.15Å; I376-F414 HydrophobicContact CG2-CE1 3.74Å; I376-F414 HydrophobicContact CG2-CZ 4.21Å; I376-M417 HydrophobicContact CG2-CE 3.67Å; I376-M417 HydrophobicContact CG2-SD 4.02Å
377	E	95.3	Very high	96.1	Very high	123 Å²	123	49.7 Å²	49.7	58%	0.575	25%	0.253	S	S	*	.	H	α-helix	trans	-64.3	-50.2	178.9	-177.5	168.8	-166.8	0	0	112.3	M373 S374 N379 S380 M417	M373-E377 PolarHBondContact O-N 2.97Å; S374-E377 PolarHBondContact O-N 3.08Å; E377-N379 PolarHBondContact O-N 3.09Å; E377-S380 WeakPolarHBondContact O-CB 3.41Å; E377-S380 PolarHBondContact O-N 3.33Å; E377-S380 PolarHBondContact O-OG 2.87Å; E377-M417 WeakPolarHBondContact CA-SD 3.44Å; E377-M417 HydrophobicContact CB-CG 4.17Å; E377-M417 HydrophobicContact CB-SD 3.76Å; E377-M417 HydrophobicContact CG-CG 3.92Å; E377-M417 HydrophobicContact CG-SD 4.2Å
378	E	95.5	Very high	96.1	Very high	136 Å²	136	49.1 Å²	49.1	64%	0.636	25%	0.251	S	S	*	.	H	α-helix	trans	-60.1	-28.5	176.7	-70	-176.7	-179	0	0	112.9	S374	S374-E378 PolarHBondContact O-N 2.99Å; S374-E378 VanDerWaalsContact O-N 3.08Å
379	N	96.2	Very high	95.9	Very high	24 Å²	24	46.1 Å²	46.1	13%	0.128	24%	0.239	C	C	.	.	T	Hydrogen-bonded Turn	trans	-115.3	22.5	-176.2	-63.3	-86.5	0	0	0	113.6	F337 Q341 L375 I376 E377 N381 V382 I383	F337-N379 HydrophobicContact CE1-CB 4.21Å; Q341-N379 PolarHBondContact NE2-OD1 3.42Å; L375-N379 WeakPolarHBondContact O-CB 3.45Å; L375-N379 PolarHBondContact O-N 3.24Å; L375-N379 PolarHBondContact O-ND2 3Å; I376-N379 CarbonylContact O-C 3.54Å; I376-N379 PolarHBondContact O-N 3.19Å; E377-N379 PolarHBondContact O-N 3.09Å; N379-N381 PolarHBondContact O-N 3.09Å; N379-N381 VanDerWaalsContact O-N 3.11Å; N379-V382 PolarHBondContact O-N 3.04Å; N379-I383 HydrophobicContact CB-CD1 3.79Å; N379-I383 HydrophobicContact CB-CG1 4.44Å; N379-I383 PolarHBondContact O-N 3.15Å; N379-I383 VanDerWaalsContact O-N 3.14Å
380	S	94.5	Very high	95.8	Very high	13 Å²	13	45.7 Å²	45.7	9%	0.091	24%	0.237	C	C	.	.	H	α-helix	trans	-54.4	-37.4	-173.9	57.1	0	0	0	0	112.9	I376 E377 V382 I383 L384 M417	I376-S380 WeakPolarHBondContact O-CA 3.4Å; I376-S380 PolarHBondContact O-N 3.03Å; E377-S380 WeakPolarHBondContact O-CB 3.41Å; E377-S380 PolarHBondContact O-N 3.33Å; E377-S380 PolarHBondContact O-OG 2.87Å; S380-V382 PolarHBondContact O-N 3.37Å; S380-V382 VanDerWaalsContact O-N 3.14Å; S380-I383 PolarHBondContact O-N 3.47Å; S380-L384 WeakPolarHBondContact O-CB 3.36Å; S380-L384 PolarHBondContact O-N 3.03Å; S380-M417 VanDerWaalsContact CB-CE 3.44Å
381	N	94	Very high	95.8	Very high	104 Å²	104	37.4 Å²	37.4	56%	0.556	20%	0.199	S	C	*	.	H	α-helix	trans	-59.6	-25.4	179.7	-65.2	-35.8	0	0	0	114.3	N379 M421	N379-N381 PolarHBondContact O-N 3.09Å; N379-N381 VanDerWaalsContact O-N 3.11Å; N381-M421 HydrophobicContact CB-CE 4.1Å; N381-M421 VanDerWaalsContact OD1-CE 3.26Å; N381-M421 WeakPolarHBondContact OD1-CE 3.4Å
382	V	96.2	Very high	95.5	Very high	53 Å²	53	35.3 Å²	35.3	32%	0.321	19%	0.19	S	C	.	.	H	α-helix	trans	-99.4	-44.2	179.4	-179.9	0	0	0	0	110.7	Q341 E342 N379 S380 I386	Q341-V382 HydrophobicContact CG-CG1 4.37Å; E342-V382 HydrophobicContact CG-CG1 3.63Å; N379-V382 PolarHBondContact O-N 3.04Å; S380-V382 PolarHBondContact O-N 3.37Å; S380-V382 VanDerWaalsContact O-N 3.14Å; V382-I386 HydrophobicContact CG1-CD1 4.32Å; V382-I386 WeakPolarHBondContact O-CD1 3.49Å; V382-I386 WeakPolarHBondContact O-CG1 3.36Å
383	I	96.5	Very high	95.2	Very high	0 Å²	0	40.2 Å²	40.2	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-76	-42.7	-170.9	-68.3	166.6	0	0	0	112	F337 F345 I376 N379 S380 I386 M387 F414	F337-I383 HydrophobicContact CE1-CD1 3.88Å; F337-I383 HydrophobicContact CZ-CD1 3.75Å; F345-I383 HydrophobicContact CD1-CG2 3.51Å; F345-I383 HydrophobicContact CD2-CD1 4.05Å; F345-I383 HydrophobicContact CD2-CG1 3.89Å; F345-I383 HydrophobicContact CD2-CG2 4.27Å; F345-I383 HydrophobicContact CE1-CG2 3.66Å; F345-I383 HydrophobicContact CE2-CD1 3.73Å; F345-I383 HydrophobicContact CE2-CG1 4.09Å; F345-I383 HydrophobicContact CE2-CG2 4.42Å; F345-I383 HydrophobicContact CG-CG1 4.18Å; F345-I383 HydrophobicContact CG-CG2 3.83Å; F345-I383 HydrophobicContact CZ-CD1 4.03Å; F345-I383 HydrophobicContact CZ-CG2 4.13Å; I376-I383 HydrophobicContact CB-CD1 4.39Å; I376-I383 HydrophobicContact CG1-CD1 4.14Å; I376-I383 HydrophobicContact CG2-CG2 4.15Å; N379-I383 HydrophobicContact CB-CD1 3.79Å; N379-I383 HydrophobicContact CB-CG1 4.44Å; N379-I383 PolarHBondContact O-N 3.15Å; N379-I383 VanDerWaalsContact O-N 3.14Å; S380-I383 PolarHBondContact O-N 3.47Å; I383-I386 WeakPolarHBondContact O-CB 3.49Å; I383-I386 PolarHBondContact O-N 2.91Å; I383-I386 VanDerWaalsContact O-N 3.12Å; I383-M387 HydrophobicContact CG2-CG 4.09Å; I383-M387 PolarHBondContact O-N 3.46Å; I383-F414 HydrophobicContact CG2-CE1 4.42Å; I383-F414 HydrophobicContact CG2-CZ 4.35Å
384	L	95.1	Very high	95.1	Very high	2 Å²	2	38.6 Å²	38.6	1%	0.01	20%	0.201	C	C	.	.	H	α-helix	trans	-62	-46.5	-173.2	-161.8	162.7	0	0	0	111.5	S380 I386 M387 F388 F414 M417 N418 M421 L425	S380-L384 WeakPolarHBondContact O-CB 3.36Å; S380-L384 PolarHBondContact O-N 3.03Å; L384-I386 VanDerWaalsContact C-N 3.27Å; L384-I386 PolarHBondContact O-N 3.41Å; L384-M387 PolarHBondContact O-N 2.89Å; L384-F388 HydrophobicContact CD2-CD2 4.38Å; L384-F388 VanDerWaalsContact O-CB 3.23Å; L384-F388 WeakPolarHBondContact O-CB 3.3Å; L384-F388 PolarHBondContact O-N 3.47Å; L384-F414 HydrophobicContact CB-CD1 4.13Å; L384-F414 HydrophobicContact CB-CE1 4.17Å; L384-F414 HydrophobicContact CD1-CB 4.11Å; L384-F414 HydrophobicContact CD1-CD1 3.62Å; L384-F414 HydrophobicContact CD1-CE1 4.44Å; L384-F414 HydrophobicContact CD1-CG 4.24Å; L384-F414 HydrophobicContact CG-CB 4.36Å; L384-F414 HydrophobicContact CG-CD1 3.57Å; L384-F414 HydrophobicContact CG-CE1 4.08Å; L384-F414 HydrophobicContact CG-CG 4.14Å; L384-M417 HydrophobicContact CD1-CE 4.27Å; L384-N418 HydrophobicContact CD1-CB 4.24Å; L384-M421 HydrophobicContact CB-SD 4.26Å; L384-M421 HydrophobicContact CD2-CG 4.21Å; L384-L425 HydrophobicContact CD2-CD1 3.09Å; L384-L425 HydrophobicContact CD2-CG 4.49Å; L384-L425 HydrophobicContact CG-CD1 4.46Å
385	P	95.1	Very high	94.9	Very high	53 Å²	53	37 Å²	37	34%	0.344	19%	0.19	S	C	.	.	H	α-helix	trans	-57.6	-34.5	173.8	-25.7	35	0	0	0	114.6	M421 L425	P385-M421 HydrophobicContact CG-SD 3.98Å; P385-L425 HydrophobicContact CB-CD1 4.31Å; P385-L425 HydrophobicContact CB-CD2 4.09Å; P385-L425 HydrophobicContact CG-CD1 4.14Å; P385-L425 HydrophobicContact CG-CD2 4.43Å
386	I	96.4	Very high	94.5	Very high	32 Å²	32	42.2 Å²	42.2	16%	0.164	21%	0.212	C	C	.	.	H	α-helix	trans	-70.7	-46.1	-180	-64.4	170.2	0	0	0	110.6	E342 F345 K346 V382 I383 L384	E342-I386 HydrophobicContact CB-CD1 4.42Å; E342-I386 HydrophobicContact CG-CD1 4.17Å; F345-I386 HydrophobicContact CB-CG2 4.15Å; K346-I386 HydrophobicContact CB-CG2 4.42Å; K346-I386 HydrophobicContact CG-CG2 3.76Å; V382-I386 HydrophobicContact CG1-CD1 4.32Å; V382-I386 WeakPolarHBondContact O-CD1 3.49Å; V382-I386 WeakPolarHBondContact O-CG1 3.36Å; I383-I386 WeakPolarHBondContact O-CB 3.49Å; I383-I386 PolarHBondContact O-N 2.91Å; I383-I386 VanDerWaalsContact O-N 3.12Å; L384-I386 VanDerWaalsContact C-N 3.27Å; L384-I386 PolarHBondContact O-N 3.41Å
387	M	96.7	Very high	94.1	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-79	-32.7	-174.1	-70.7	-58.2	-50.6	0	0	113.5	F345 I348 A349 V352 W367 I383 L384 S389 S390 L391 F414	F345-M387 HydrophobicContact CB-CG 4.45Å; F345-M387 HydrophobicContact CB-SD 4.26Å; F345-M387 HydrophobicContact CD1-CG 3.78Å; F345-M387 HydrophobicContact CD1-SD 3.82Å; I348-M387 HydrophobicContact CB-SD 4.39Å; I348-M387 HydrophobicContact CG2-CE 4.19Å; I348-M387 HydrophobicContact CG2-SD 4.28Å; A349-M387 HydrophobicContact CB-CE 4.19Å; A349-M387 HydrophobicContact CB-SD 3.68Å; V352-M387 HydrophobicContact CB-CE 4.49Å; V352-M387 HydrophobicContact CG2-CE 4.11Å; W367-M387 HydrophobicContact CH2-CE 3.57Å; W367-M387 HydrophobicContact CH2-SD 4.43Å; W367-M387 HydrophobicContact CZ2-CE 4.18Å; I383-M387 HydrophobicContact CG2-CG 4.09Å; I383-M387 PolarHBondContact O-N 3.46Å; L384-M387 PolarHBondContact O-N 2.89Å; M387-S389 PolarHBondContact O-N 2.94Å; M387-S390 PolarHBondContact O-N 3.36Å; M387-S390 VanDerWaalsContact O-N 3.14Å; M387-L391 HydrophobicContact CB-CD1 3.95Å; M387-L391 HydrophobicContact CE-CD1 4.26Å; M387-L391 HydrophobicContact CE-CG 4.31Å; M387-L391 PolarHBondContact O-N 3.01Å; M387-L391 VanDerWaalsContact O-N 3.12Å; M387-F414 HydrophobicContact CB-CE2 4.27Å; M387-F414 HydrophobicContact CB-CZ 4.2Å; M387-F414 HydrophobicContact CG-CZ 4.39Å
388	F	95.1	Very high	94	Very high	8 Å²	8	42.3 Å²	42.3	4%	0.035	21%	0.213	C	C	.	.	H	α-helix	trans	-54	-50.3	-168	-176.7	-89.5	0	0	0	113.3	L384 S390 L391 Y392 F422 L425 T426 Y429	L384-F388 HydrophobicContact CD2-CD2 4.38Å; L384-F388 VanDerWaalsContact O-CB 3.23Å; L384-F388 WeakPolarHBondContact O-CB 3.3Å; L384-F388 PolarHBondContact O-N 3.47Å; F388-S390 PolarHBondContact O-N 2.91Å; F388-L391 PolarHBondContact O-N 3.27Å; F388-Y392 HydrophobicContact CE1-CD2 4.37Å; F388-Y392 HydrophobicContact CE1-CG 4.2Å; F388-Y392 AromaticContact CZ-CD2 3.89Å; F388-Y392 HydrophobicContact CZ-CD2 3.89Å; F388-Y392 HydrophobicContact CZ-CG 4.18Å; F388-Y392 VanDerWaalsContact O-CB 3.27Å; F388-Y392 WeakPolarHBondContact O-CB 3.14Å; F388-Y392 PolarHBondContact O-N 3.25Å; F388-F422 HydrophobicContact CD2-CD2 4.19Å; F388-F422 HydrophobicContact CD2-CE2 4.13Å; F388-F422 AromaticContact CE2-CD2 3.95Å; F388-F422 HydrophobicContact CE2-CD2 3.95Å; F388-F422 HydrophobicContact CE2-CE1 4.29Å; F388-F422 AromaticContact CE2-CE2 3.73Å; F388-F422 HydrophobicContact CE2-CE2 3.73Å; F388-F422 HydrophobicContact CE2-CG 4.34Å; F388-F422 AromaticContact CE2-CZ 3.91Å; F388-F422 HydrophobicContact CE2-CZ 3.91Å; F388-L425 HydrophobicContact CB-CB 4.49Å; F388-L425 HydrophobicContact CB-CD1 4.13Å; F388-L425 HydrophobicContact CD1-CB 3.86Å; F388-L425 HydrophobicContact CD2-CB 4.08Å; F388-L425 HydrophobicContact CD2-CD1 4.48Å; F388-L425 HydrophobicContact CE1-CB 4.13Å; F388-L425 WeakPolarHBondContact CE1-O 3.11Å; F388-L425 HydrophobicContact CE2-CB 4.32Å; F388-L425 HydrophobicContact CG-CB 3.87Å; F388-L425 HydrophobicContact CG-CD1 4.28Å; F388-L425 HydrophobicContact CZ-CB 4.36Å; F388-T426 WeakPolarHBondContact CZ-OG1 3.45Å; F388-Y429 HydrophobicContact CE1-CD2 4.48Å; F388-Y429 HydrophobicContact CE1-CG 4.17Å
389	S	92.7	Very high	93.9	Very high	54 Å²	54	43.9 Å²	43.9	38%	0.378	21%	0.213	S	C	.	.	H	α-helix	trans	-59	-36.5	-176.5	64.6	0	0	0	0	113.2	M387 R393	M387-S389 PolarHBondContact O-N 2.94Å; S389-R393 WeakPolarHBondContact O-CB 3.13Å; S389-R393 PolarHBondContact O-N 3.2Å
390	S	94.3	Very high	93.9	Very high	13 Å²	13	44.1 Å²	44.1	9%	0.091	21%	0.214	C	C	.	.	H	α-helix	trans	-74.1	-52.1	-179.3	-69.5	0	0	0	0	110.8	A349 S353 M387 F388 Y392 R393 I394	A349-S390 WeakPolarHBondContact O-CB 3.29Å; A349-S390 PolarHBondContact O-OG 3.45Å; S353-S390 VanDerWaalsContact OG-CB 3.23Å; S353-S390 WeakPolarHBondContact OG-CB 3.45Å; S353-S390 PolarHBondContact OG-OG 3.44Å; M387-S390 PolarHBondContact O-N 3.36Å; M387-S390 VanDerWaalsContact O-N 3.14Å; F388-S390 PolarHBondContact O-N 2.91Å; S390-Y392 PolarHBondContact O-N 2.89Å; S390-R393 PolarHBondContact O-N 3.19Å; S390-I394 WeakPolarHBondContact O-CG1 3.23Å; S390-I394 PolarHBondContact O-N 3.43Å
391	L	95.2	Very high	93.9	Very high	0 Å²	0	48.3 Å²	48.3	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-59	-48	177.8	-71.3	162.2	0	0	0	111.8	V352 L364 M387 F388 R393 I394 S395 V407 V410 L411 F414	V352-L391 HydrophobicContact CG1-CD2 3.69Å; V352-L391 HydrophobicContact CG1-CG 4.39Å; L364-L391 HydrophobicContact CD2-CD2 3.93Å; M387-L391 HydrophobicContact CB-CD1 3.95Å; M387-L391 HydrophobicContact CE-CD1 4.26Å; M387-L391 HydrophobicContact CE-CG 4.31Å; M387-L391 PolarHBondContact O-N 3.01Å; M387-L391 VanDerWaalsContact O-N 3.12Å; F388-L391 PolarHBondContact O-N 3.27Å; L391-R393 VanDerWaalsContact C-N 3.32Å; L391-R393 PolarHBondContact O-N 3.02Å; L391-I394 PolarHBondContact O-N 3.36Å; L391-S395 PolarHBondContact O-N 3.1Å; L391-V407 HydrophobicContact CB-CG1 4.2Å; L391-V407 HydrophobicContact CD2-CG1 3.99Å; L391-V407 HydrophobicContact CD2-CG2 4.29Å; L391-V407 WeakPolarHBondContact O-CG1 3.37Å; L391-V410 HydrophobicContact CD1-CG1 3.7Å; L391-V410 HydrophobicContact CD2-CB 4.21Å; L391-V410 HydrophobicContact CD2-CG1 3.71Å; L391-V410 HydrophobicContact CG-CG1 4.38Å; L391-L411 HydrophobicContact CB-CD2 3.71Å; L391-L411 HydrophobicContact CB-CG 4.11Å; L391-L411 HydrophobicContact CD1-CD2 4.46Å; L391-F414 HydrophobicContact CD1-CD2 3.8Å; L391-F414 HydrophobicContact CD1-CE2 3.54Å
392	Y	92.8	Very high	94	Very high	37 Å²	37	46 Å²	46	15%	0.145	24%	0.236	C	C	.	.	H	α-helix	trans	-64.3	-36	-177.3	-164.2	-95.7	0	0	0	112.4	F388 S390 S395 K396 Y429	F388-Y392 HydrophobicContact CE1-CD2 4.37Å; F388-Y392 HydrophobicContact CE1-CG 4.2Å; F388-Y392 AromaticContact CZ-CD2 3.89Å; F388-Y392 HydrophobicContact CZ-CD2 3.89Å; F388-Y392 HydrophobicContact CZ-CG 4.18Å; F388-Y392 VanDerWaalsContact O-CB 3.27Å; F388-Y392 WeakPolarHBondContact O-CB 3.14Å; F388-Y392 PolarHBondContact O-N 3.25Å; S390-Y392 PolarHBondContact O-N 2.89Å; Y392-S395 PolarHBondContact O-OG 3.14Å; Y392-K396 HydrophobicContact CE1-CD 4.4Å; Y392-K396 VanDerWaalsContact CE1-CE 3.45Å; Y392-K396 VanDerWaalsContact CZ-NZ 3.32Å; Y392-K396 PolarHBondContact OH-NZ 3.47Å; Y392-Y429 AromaticContact CD1-CD1 3.59Å; Y392-Y429 HydrophobicContact CD1-CD1 3.59Å; Y392-Y429 AromaticContact CD1-CE1 3.38Å; Y392-Y429 HydrophobicContact CD1-CE1 3.38Å; Y392-Y429 HydrophobicContact CD1-CG 4.36Å; Y392-Y429 AromaticContact CD1-CZ 3.98Å; Y392-Y429 AromaticContact CE1-CD1 3.87Å; Y392-Y429 HydrophobicContact CE1-CD1 3.87Å; Y392-Y429 AromaticContact CE1-CE1 3.84Å; Y392-Y429 HydrophobicContact CE1-CE1 3.84Å; Y392-Y429 HydrophobicContact CG-CE1 4.47Å
393	R	91.5	Very high	94	Very high	104 Å²	104	43.5 Å²	43.5	39%	0.392	22%	0.221	S	C	.	.	H	α-helix	trans	-64.7	-51.7	173.2	-177.8	179.8	58.4	-168.1	-5	111.6	S353 S389 S390 L391 S395 K396 E397	S353-R393 VanDerWaalsContact CB-NH2 3.3Å; S353-R393 PolarHBondContact OG-NH2 3Å; S389-R393 WeakPolarHBondContact O-CB 3.13Å; S389-R393 PolarHBondContact O-N 3.2Å; S390-R393 PolarHBondContact O-N 3.19Å; L391-R393 VanDerWaalsContact C-N 3.32Å; L391-R393 PolarHBondContact O-N 3.02Å; R393-S395 VanDerWaalsContact C-N 3.29Å; R393-S395 PolarHBondContact O-N 2.98Å; R393-K396 PolarHBondContact O-N 3.41Å; R393-E397 VanDerWaalsContact CG-OE2 3.26Å; R393-E397 WeakPolarHBondContact CG-OE2 3.3Å; R393-E397 PolarHBondContact O-N 2.95Å
394	I	92.4	Very high	94	Very high	12 Å²	12	44.8 Å²	44.8	6%	0.062	23%	0.229	C	C	.	.	H	α-helix	trans	-64.9	-33.2	-175	-63.2	-64.3	0	0	0	111.6	S390 L391 K396 E397 H398 I403 V407	S390-I394 WeakPolarHBondContact O-CG1 3.23Å; S390-I394 PolarHBondContact O-N 3.43Å; L391-I394 PolarHBondContact O-N 3.36Å; I394-K396 PolarHBondContact O-N 3.25Å; I394-E397 PolarHBondContact O-N 2.99Å; I394-H398 HydrophobicContact CG2-CB 3.69Å; I394-H398 VanDerWaalsContact O-CB 3.27Å; I394-H398 WeakPolarHBondContact O-CB 3.41Å; I394-H398 PolarHBondContact O-N 3.09Å; I394-H398 VanDerWaalsContact O-N 3.12Å; I394-I403 HydrophobicContact CG2-CG2 4.18Å; I394-V407 HydrophobicContact CB-CG2 4.44Å; I394-V407 HydrophobicContact CG2-CG2 3.8Å
395	S	92.4	Very high	94	Very high	6 Å²	6	47.1 Å²	47.1	4%	0.042	25%	0.248	C	C	.	.	H	α-helix	trans	-57.3	-20.8	173.8	74.9	0	0	0	0	114.5	L391 Y392 R393 Y408	L391-S395 PolarHBondContact O-N 3.1Å; Y392-S395 PolarHBondContact O-OG 3.14Å; R393-S395 VanDerWaalsContact C-N 3.29Å; R393-S395 PolarHBondContact O-N 2.98Å; S395-Y408 PolarHBondContact O-OH 3.33Å
396	K	89.5	Confident	94.1	Very high	112 Å²	112	46.2 Å²	46.2	49%	0.487	24%	0.24	S	C	.	.	H	α-helix	trans	-109.7	-26.2	-177	-61.5	-173.5	-177.2	-170.5	0	114.1	Y392 R393 I394	Y392-K396 HydrophobicContact CE1-CD 4.4Å; Y392-K396 VanDerWaalsContact CE1-CE 3.45Å; Y392-K396 VanDerWaalsContact CZ-NZ 3.32Å; Y392-K396 PolarHBondContact OH-NZ 3.47Å; R393-K396 PolarHBondContact O-N 3.41Å; I394-K396 PolarHBondContact O-N 3.25Å
397	E	89.4	Confident	94.1	Very high	105 Å²	105	44.7 Å²	44.7	49%	0.491	23%	0.233	S	C	.	.	H	α-helix	trans	-123.3	-7.2	-162.5	-66.5	171.4	-168.7	0	0	113.2	R393 I394 R433	R393-E397 VanDerWaalsContact CG-OE2 3.26Å; R393-E397 WeakPolarHBondContact CG-OE2 3.3Å; R393-E397 PolarHBondContact O-N 2.95Å; I394-E397 PolarHBondContact O-N 2.99Å; E397-R433 IonicContact OE1-CZ 3.31Å; E397-R433 IonicContact OE1-NH1 2.88Å; E397-R433 IonicContact OE1-NH2 2.65Å; E397-R433 PolarHBondContact OE1-NH2 2.96Å
398	H	91.5	Very high	94.1	Very high	21 Å²	21	50.7 Å²	50.7	10%	0.097	26%	0.256	C	S	.	.			trans	-75.1	135.4	-178.8	-161.3	-86	0	0	0	112.3	S354 I394 N400 V404	S354-H398 PolarHBondContact O-NE2 3.11Å; I394-H398 HydrophobicContact CG2-CB 3.69Å; I394-H398 VanDerWaalsContact O-CB 3.27Å; I394-H398 WeakPolarHBondContact O-CB 3.41Å; I394-H398 PolarHBondContact O-N 3.09Å; I394-H398 VanDerWaalsContact O-N 3.12Å; H398-N400 PolarHBondContact ND1-N 3.41Å; H398-N400 PolarHBondContact ND1-O 2.99Å; H398-V404 HydrophobicContact CB-CG2 3.83Å
399	W	95.4	Very high	94.1	Very high	168 Å²	168	55.4 Å²	55.4	64%	0.636	28%	0.282	S	S	*	.	S	Bend	trans	-72.7	-29	-175.4	69.7	-92.6	0	0	0	113.5	P355 F357 P401	P355-W399 PolarHBondContact O-NE1 3.14Å; F357-W399 HydrophobicContact CB-CZ2 4.27Å; W399-P401 WeakPolarHBondContact O-CD 3.49Å
400	N	95.1	Very high	94.2	Very high	29 Å²	29	53.1 Å²	53.1	16%	0.155	27%	0.265	C	S	.	.			trans	-91	116.8	-180	-174.1	-25.6	0	0	0	110.9	H398 A402 I403 V404	H398-N400 PolarHBondContact ND1-N 3.41Å; H398-N400 PolarHBondContact ND1-O 2.99Å; N400-A402 VanDerWaalsContact C-N 3.32Å; N400-A402 PolarHBondContact O-N 2.97Å; N400-A402 WeakPolarHBondContact OD1-CB 3.33Å; N400-A402 PolarHBondContact OD1-N 3.47Å; N400-I403 HydrophobicContact CB-CB 4.44Å; N400-I403 HydrophobicContact CB-CG1 3.96Å; N400-I403 PolarHBondContact O-N 2.76Å; N400-V404 PolarHBondContact O-N 2.85Å
401	P	95.4	Very high	94.3	Very high	102 Å²	102	53.1 Å²	53.1	66%	0.662	26%	0.264	S	S	*	.	H	α-helix	trans	-62.3	-30.4	-179.8	-23.7	34.7	0	0	0	115.1	W399 V404 A405	W399-P401 WeakPolarHBondContact O-CD 3.49Å; P401-V404 WeakPolarHBondContact O-CB 3.26Å; P401-V404 PolarHBondContact O-N 2.86Å; P401-A405 PolarHBondContact O-N 3.36Å
402	A	96	Very high	94.2	Very high	54 Å²	54	58.7 Å²	58.7	45%	0.446	29%	0.289	S	S	.	.	H	α-helix	trans	-65.6	-42.2	179	0	0	0	0	0	111.2	N400 V404 A405 L406	N400-A402 VanDerWaalsContact C-N 3.32Å; N400-A402 PolarHBondContact O-N 2.97Å; N400-A402 WeakPolarHBondContact OD1-CB 3.33Å; N400-A402 PolarHBondContact OD1-N 3.47Å; A402-V404 VanDerWaalsContact C-N 3.33Å; A402-V404 PolarHBondContact O-N 3.05Å; A402-A405 PolarHBondContact O-N 3.17Å; A402-L406 PolarHBondContact O-N 3.32Å
403	I	96.4	Very high	94.3	Very high	1 Å²	1	58.1 Å²	58.1	1%	0.005	29%	0.292	C	S	.	.	H	α-helix	trans	-62.9	-42.6	174.1	-56.7	-55.7	0	0	0	110.5	F357 A360 E361 L364 I394 N400 A405 L406 V407	F357-I403 HydrophobicContact CB-CD1 4.37Å; F357-I403 HydrophobicContact CB-CG1 4.25Å; A360-I403 HydrophobicContact CB-CD1 4.2Å; A360-I403 HydrophobicContact CB-CG2 3.99Å; E361-I403 HydrophobicContact CB-CD1 3.73Å; L364-I403 HydrophobicContact CD1-CG2 3.91Å; I394-I403 HydrophobicContact CG2-CG2 4.18Å; N400-I403 HydrophobicContact CB-CB 4.44Å; N400-I403 HydrophobicContact CB-CG1 3.96Å; N400-I403 PolarHBondContact O-N 2.76Å; I403-A405 VanDerWaalsContact C-N 3.3Å; I403-A405 PolarHBondContact O-N 3.12Å; I403-L406 PolarHBondContact O-N 2.74Å; I403-V407 HydrophobicContact CG2-CG2 4.36Å; I403-V407 VanDerWaalsContact O-CG2 3.29Å; I403-V407 WeakPolarHBondContact O-CG2 3.44Å; I403-V407 PolarHBondContact O-N 3.26Å
404	V	96	Very high	94.4	Very high	28 Å²	28	53.4 Å²	53.4	17%	0.17	27%	0.274	C	S	.	.	H	α-helix	trans	-57.8	-44.2	175.9	173.9	0	0	0	0	110.9	H398 N400 P401 A402 V407 Y408	H398-V404 HydrophobicContact CB-CG2 3.83Å; N400-V404 PolarHBondContact O-N 2.85Å; P401-V404 WeakPolarHBondContact O-CB 3.26Å; P401-V404 PolarHBondContact O-N 2.86Å; A402-V404 VanDerWaalsContact C-N 3.33Å; A402-V404 PolarHBondContact O-N 3.05Å; V404-V407 PolarHBondContact O-N 3.07Å; V404-Y408 HydrophobicContact CG1-CD2 3.73Å; V404-Y408 HydrophobicContact CG1-CE2 3.39Å; V404-Y408 WeakPolarHBondContact O-CD2 3.46Å; V404-Y408 PolarHBondContact O-N 3.28Å
405	A	95.9	Very high	94.5	Very high	50 Å²	50	56.8 Å²	56.8	41%	0.413	29%	0.29	S	S	.	.	H	α-helix	trans	-63.2	-44.9	177.1	0	0	0	0	0	112.7	P401 A402 I403 V407 Y408 N409	P401-A405 PolarHBondContact O-N 3.36Å; A402-A405 PolarHBondContact O-N 3.17Å; I403-A405 VanDerWaalsContact C-N 3.3Å; I403-A405 PolarHBondContact O-N 3.12Å; A405-V407 VanDerWaalsContact C-N 3.33Å; A405-V407 PolarHBondContact O-N 3.03Å; A405-Y408 PolarHBondContact O-N 3.35Å; A405-N409 PolarHBondContact O-N 3.07Å; A405-N409 VanDerWaalsContact O-N 3.11Å
406	L	96.5	Very high	94.5	Very high	34 Å²	34	62.9 Å²	62.9	18%	0.178	32%	0.318	C	S	.	.	H	α-helix	trans	-59.6	-43.8	174.8	-70.9	174.4	0	0	0	111.6	E361 L364 Y365 A402 I403 Y408 N409 V410	E361-L406 HydrophobicContact CG-CD1 4.09Å; L364-L406 HydrophobicContact CB-CB 4.27Å; L364-L406 HydrophobicContact CB-CD1 4.44Å; L364-L406 HydrophobicContact CD1-CB 3.82Å; L364-L406 HydrophobicContact CD1-CD1 4.43Å; Y365-L406 HydrophobicContact CE1-CD1 4.15Å; Y365-L406 HydrophobicContact CE1-CD2 4.04Å; A402-L406 PolarHBondContact O-N 3.32Å; I403-L406 PolarHBondContact O-N 2.74Å; L406-Y408 VanDerWaalsContact C-N 3.33Å; L406-Y408 PolarHBondContact O-N 3.34Å; L406-N409 WeakPolarHBondContact O-CB 3.21Å; L406-N409 PolarHBondContact O-N 3.35Å; L406-V410 WeakPolarHBondContact O-CG2 3.23Å; L406-V410 PolarHBondContact O-N 2.95Å
407	V	96.8	Very high	94.5	Very high	0 Å²	0	59.3 Å²	59.3	0%	0	30%	0.304	C	S	.	.	H	α-helix	trans	-61.9	-39.8	176.6	170.8	0	0	0	0	111.8	V352 L364 L391 I394 I403 V404 A405 N409 V410 L411	V352-V407 HydrophobicContact CG1-CG2 4.45Å; L364-V407 HydrophobicContact CD1-CG2 3.67Å; L364-V407 HydrophobicContact CD2-CG2 3.88Å; L364-V407 HydrophobicContact CG-CG2 4.44Å; L391-V407 HydrophobicContact CB-CG1 4.2Å; L391-V407 HydrophobicContact CD2-CG1 3.99Å; L391-V407 HydrophobicContact CD2-CG2 4.29Å; L391-V407 WeakPolarHBondContact O-CG1 3.37Å; I394-V407 HydrophobicContact CB-CG2 4.44Å; I394-V407 HydrophobicContact CG2-CG2 3.8Å; I403-V407 HydrophobicContact CG2-CG2 4.36Å; I403-V407 VanDerWaalsContact O-CG2 3.29Å; I403-V407 WeakPolarHBondContact O-CG2 3.44Å; I403-V407 PolarHBondContact O-N 3.26Å; V404-V407 PolarHBondContact O-N 3.07Å; A405-V407 VanDerWaalsContact C-N 3.33Å; A405-V407 PolarHBondContact O-N 3.03Å; V407-N409 VanDerWaalsContact C-N 3.34Å; V407-N409 PolarHBondContact O-N 2.95Å; V407-V410 PolarHBondContact O-N 3.11Å; V407-L411 HydrophobicContact CG1-CD1 3.98Å; V407-L411 HydrophobicContact CG1-CG 4.3Å; V407-L411 WeakPolarHBondContact O-CB 3.27Å; V407-L411 WeakPolarHBondContact O-CG 3.42Å; V407-L411 PolarHBondContact O-N 3.05Å
408	Y	95.3	Very high	94.5	Very high	127 Å²	127	55.9 Å²	55.9	50%	0.498	29%	0.289	S	S	.	.	H	α-helix	trans	-62.1	-40.8	174.9	-83.6	-64.3	0	0	0	112.3	S395 V404 A405 L406 V410 L411 K412	S395-Y408 PolarHBondContact O-OH 3.33Å; V404-Y408 HydrophobicContact CG1-CD2 3.73Å; V404-Y408 HydrophobicContact CG1-CE2 3.39Å; V404-Y408 WeakPolarHBondContact O-CD2 3.46Å; V404-Y408 PolarHBondContact O-N 3.28Å; A405-Y408 PolarHBondContact O-N 3.35Å; L406-Y408 VanDerWaalsContact C-N 3.33Å; L406-Y408 PolarHBondContact O-N 3.34Å; Y408-V410 VanDerWaalsContact C-N 3.35Å; Y408-L411 PolarHBondContact O-N 2.95Å; Y408-K412 WeakPolarHBondContact O-CB 3.2Å; Y408-K412 PolarHBondContact O-N 3.38Å
409	N	95.1	Very high	94.6	Very high	106 Å²	106	58 Å²	58	57%	0.567	31%	0.306	S	S	*	.	H	α-helix	trans	-61.5	-44.4	175.2	-67.8	-17.7	0	0	0	111.3	A405 L406 V407 K412 A413	A405-N409 PolarHBondContact O-N 3.07Å; A405-N409 VanDerWaalsContact O-N 3.11Å; L406-N409 WeakPolarHBondContact O-CB 3.21Å; L406-N409 PolarHBondContact O-N 3.35Å; V407-N409 VanDerWaalsContact C-N 3.34Å; V407-N409 PolarHBondContact O-N 2.95Å; N409-K412 WeakPolarHBondContact O-CB 3.49Å; N409-K412 PolarHBondContact O-N 3.45Å; N409-A413 PolarHBondContact O-N 3.13Å
410	V	96.2	Very high	94.5	Very high	6 Å²	6	54.1 Å²	54.1	4%	0.036	30%	0.301	C	S	.	.	H	α-helix	trans	-63.6	-44.6	176.8	171.1	0	0	0	0	112.1	L364 W367 L391 L406 V407 Y408 K412 A413 F414	L364-V410 HydrophobicContact CD2-CB 4.41Å; L364-V410 HydrophobicContact CD2-CG2 3.83Å; W367-V410 HydrophobicContact CB-CG2 3.81Å; W367-V410 HydrophobicContact CD2-CB 4.28Å; W367-V410 HydrophobicContact CD2-CG1 3.59Å; W367-V410 HydrophobicContact CD2-CG2 3.67Å; W367-V410 HydrophobicContact CE3-CG1 4.21Å; W367-V410 HydrophobicContact CE3-CG2 3.95Å; W367-V410 HydrophobicContact CG-CB 4.26Å; W367-V410 HydrophobicContact CG-CG1 3.89Å; W367-V410 HydrophobicContact CG-CG2 3.58Å; W367-V410 HydrophobicContact CH2-CG1 4.47Å; W367-V410 HydrophobicContact CZ2-CG1 3.87Å; L391-V410 HydrophobicContact CD1-CG1 3.7Å; L391-V410 HydrophobicContact CD2-CB 4.21Å; L391-V410 HydrophobicContact CD2-CG1 3.71Å; L391-V410 HydrophobicContact CG-CG1 4.38Å; L406-V410 WeakPolarHBondContact O-CG2 3.23Å; L406-V410 PolarHBondContact O-N 2.95Å; V407-V410 PolarHBondContact O-N 3.11Å; Y408-V410 VanDerWaalsContact C-N 3.35Å; V410-K412 VanDerWaalsContact C-N 3.28Å; V410-K412 PolarHBondContact O-N 2.89Å; V410-A413 PolarHBondContact O-N 3.36Å; V410-F414 HydrophobicContact CG1-CD2 3.79Å; V410-F414 HydrophobicContact CG1-CE2 3.71Å; V410-F414 WeakPolarHBondContact O-CD2 3.41Å; V410-F414 PolarHBondContact O-N 2.8Å
411	L	95.3	Very high	94.4	Very high	13 Å²	13	54.4 Å²	54.4	7%	0.068	30%	0.302	C	S	.	.	H	α-helix	trans	-60.8	-39	175.8	-76.6	171.5	0	0	0	111.6	L391 V407 Y408 F414 M415 F422	L391-L411 HydrophobicContact CB-CD2 3.71Å; L391-L411 HydrophobicContact CB-CG 4.11Å; L391-L411 HydrophobicContact CD1-CD2 4.46Å; V407-L411 HydrophobicContact CG1-CD1 3.98Å; V407-L411 HydrophobicContact CG1-CG 4.3Å; V407-L411 WeakPolarHBondContact O-CB 3.27Å; V407-L411 WeakPolarHBondContact O-CG 3.42Å; V407-L411 PolarHBondContact O-N 3.05Å; Y408-L411 PolarHBondContact O-N 2.95Å; L411-F414 PolarHBondContact O-N 2.97Å; L411-M415 WeakPolarHBondContact O-CB 3.48Å; L411-M415 PolarHBondContact O-N 3.29Å; L411-F422 HydrophobicContact CB-CE2 4.47Å; L411-F422 HydrophobicContact CB-CZ 4.48Å; L411-F422 HydrophobicContact CD2-CE2 3.97Å; L411-F422 HydrophobicContact CD2-CZ 4.22Å; L411-F422 WeakPolarHBondContact O-CE2 3.26Å
412	K	94.3	Very high	94.3	Very high	117 Å²	117	50.6 Å²	50.6	51%	0.509	28%	0.275	S	S	.	.	H	α-helix	trans	-63.4	-45.7	175.5	-171	-173.8	-180	-147.2	0	111.3	Y408 N409 V410 F414 M415 E416	Y408-K412 WeakPolarHBondContact O-CB 3.2Å; Y408-K412 PolarHBondContact O-N 3.38Å; N409-K412 WeakPolarHBondContact O-CB 3.49Å; N409-K412 PolarHBondContact O-N 3.45Å; V410-K412 VanDerWaalsContact C-N 3.28Å; V410-K412 PolarHBondContact O-N 2.89Å; K412-F414 VanDerWaalsContact C-N 3.34Å; K412-F414 PolarHBondContact O-N 3.37Å; K412-M415 HydrophobicContact CG-CE 4.5Å; K412-M415 WeakPolarHBondContact O-CB 3.2Å; K412-M415 PolarHBondContact O-N 3.12Å; K412-M415 VanDerWaalsContact O-N 3.17Å; K412-E416 WeakPolarHBondContact CE-OE1 3.43Å; K412-E416 IonicContact NZ-OE1 3.34Å; K412-E416 PolarHBondContact NZ-OE1 3.14Å; K412-E416 WeakPolarHBondContact O-CG 3.23Å; K412-E416 PolarHBondContact O-N 3.23Å
413	A	93.8	Very high	94.1	Very high	25 Å²	25	52.9 Å²	52.9	21%	0.207	28%	0.28	C	S	.	.	H	α-helix	trans	-59.4	-43.8	176.3	0	0	0	0	0	111.9	M373 N409 V410 M415 E416 M417	M373-A413 HydrophobicContact CE-CB 4.25Å; N409-A413 PolarHBondContact O-N 3.13Å; V410-A413 PolarHBondContact O-N 3.36Å; A413-M415 VanDerWaalsContact C-N 3.32Å; A413-M415 PolarHBondContact O-N 2.93Å; A413-E416 PolarHBondContact O-N 3.05Å; A413-M417 WeakPolarHBondContact O-CB 3.23Å; A413-M417 PolarHBondContact O-N 3.29Å
414	F	94	Very high	94	Very high	5 Å²	5	58.4 Å²	58.4	2%	0.022	31%	0.306	C	S	.	.	H	α-helix	trans	-61.9	-38.2	175	-85.6	-58.7	0	0	0	113.5	W367 I376 I383 L384 M387 L391 V410 L411 K412 M417 N418 F422	W367-F414 AromaticContact CE2-CE2 3.63Å; W367-F414 AromaticContact CE2-CZ 3.89Å; W367-F414 AromaticContact CZ2-CE2 3.48Å; W367-F414 HydrophobicContact CZ2-CE2 3.48Å; W367-F414 VanDerWaalsContact CZ2-CE2 3.48Å; W367-F414 AromaticContact CZ2-CZ 3.63Å; W367-F414 HydrophobicContact CZ2-CZ 3.63Å; W367-F414 AromaticContact NE1-CE2 3.35Å; W367-F414 VanDerWaalsContact NE1-CE2 3.35Å; W367-F414 AromaticContact NE1-CZ 3.54Å; I376-F414 HydrophobicContact CG2-CE1 3.74Å; I376-F414 HydrophobicContact CG2-CZ 4.21Å; I383-F414 HydrophobicContact CG2-CE1 4.42Å; I383-F414 HydrophobicContact CG2-CZ 4.35Å; L384-F414 HydrophobicContact CB-CD1 4.13Å; L384-F414 HydrophobicContact CB-CE1 4.17Å; L384-F414 HydrophobicContact CD1-CB 4.11Å; L384-F414 HydrophobicContact CD1-CD1 3.62Å; L384-F414 HydrophobicContact CD1-CE1 4.44Å; L384-F414 HydrophobicContact CD1-CG 4.24Å; L384-F414 HydrophobicContact CG-CB 4.36Å; L384-F414 HydrophobicContact CG-CD1 3.57Å; L384-F414 HydrophobicContact CG-CE1 4.08Å; L384-F414 HydrophobicContact CG-CG 4.14Å; M387-F414 HydrophobicContact CB-CE2 4.27Å; M387-F414 HydrophobicContact CB-CZ 4.2Å; M387-F414 HydrophobicContact CG-CZ 4.39Å; L391-F414 HydrophobicContact CD1-CD2 3.8Å; L391-F414 HydrophobicContact CD1-CE2 3.54Å; V410-F414 HydrophobicContact CG1-CD2 3.79Å; V410-F414 HydrophobicContact CG1-CE2 3.71Å; V410-F414 WeakPolarHBondContact O-CD2 3.41Å; V410-F414 PolarHBondContact O-N 2.8Å; L411-F414 PolarHBondContact O-N 2.97Å; K412-F414 VanDerWaalsContact C-N 3.34Å; K412-F414 PolarHBondContact O-N 3.37Å; F414-M417 HydrophobicContact CD1-CE 3.41Å; F414-M417 VanDerWaalsContact CD1-CE 3.41Å; F414-M417 HydrophobicContact CE1-CE 3.62Å; F414-M417 PolarHBondContact O-N 3.39Å; F414-N418 PolarHBondContact O-N 3.11Å; F414-N418 VanDerWaalsContact O-N 3.1Å; F414-F422 HydrophobicContact CB-CD2 4.11Å; F414-F422 HydrophobicContact CB-CE2 4.29Å
415	M	93.3	Very high	93.9	Very high	83 Å²	83	58.6 Å²	58.6	41%	0.409	31%	0.305	S	S	.	.	H	α-helix	trans	-68.1	-39.8	177.3	-175.8	-176	69.2	0	0	112	L411 K412 A413 M417 S419 F422	L411-M415 WeakPolarHBondContact O-CB 3.48Å; L411-M415 PolarHBondContact O-N 3.29Å; K412-M415 HydrophobicContact CG-CE 4.5Å; K412-M415 WeakPolarHBondContact O-CB 3.2Å; K412-M415 PolarHBondContact O-N 3.12Å; K412-M415 VanDerWaalsContact O-N 3.17Å; A413-M415 VanDerWaalsContact C-N 3.32Å; A413-M415 PolarHBondContact O-N 2.93Å; M415-M417 VanDerWaalsContact C-N 3.31Å; M415-S419 VanDerWaalsContact O-CA 3.3Å; M415-S419 WeakPolarHBondContact O-CA 2.92Å; M415-S419 WeakPolarHBondContact O-CB 3.41Å; M415-S419 PolarHBondContact O-N 3.47Å; M415-F422 HydrophobicContact CB-CD1 4.13Å; M415-F422 HydrophobicContact CB-CD2 4.05Å; M415-F422 HydrophobicContact CB-CE1 4.27Å; M415-F422 HydrophobicContact CB-CE2 4.18Å; M415-F422 HydrophobicContact CB-CG 4.01Å; M415-F422 HydrophobicContact CB-CZ 4.29Å; M415-F422 HydrophobicContact CG-CD1 4.04Å; M415-F422 HydrophobicContact CG-CE1 4.33Å; M415-F422 HydrophobicContact CG-CG 4.28Å; M415-F422 HydrophobicContact SD-CE1 4.45Å
416	E	92.6	Very high	93.8	Very high	135 Å²	135	57.1 Å²	57.1	63%	0.631	29%	0.291	S	S	*	.	H	α-helix	trans	-66.3	-34.6	175.7	-72	173.3	-178.2	0	0	111.7	K412 A413	K412-E416 WeakPolarHBondContact CE-OE1 3.43Å; K412-E416 IonicContact NZ-OE1 3.34Å; K412-E416 PolarHBondContact NZ-OE1 3.14Å; K412-E416 WeakPolarHBondContact O-CG 3.23Å; K412-E416 PolarHBondContact O-N 3.23Å; A413-E416 PolarHBondContact O-N 3.05Å
417	M	90.5	Very high	93.5	Very high	36 Å²	36	58.4 Å²	58.4	18%	0.177	31%	0.307	C	S	.	.	H	α-helix	trans	-73.7	-43.8	-179.2	-172.2	172.3	80.1	0	0	113.9	I376 E377 S380 L384 A413 F414 M415	I376-M417 HydrophobicContact CG2-CE 3.67Å; I376-M417 HydrophobicContact CG2-SD 4.02Å; E377-M417 WeakPolarHBondContact CA-SD 3.44Å; E377-M417 HydrophobicContact CB-CG 4.17Å; E377-M417 HydrophobicContact CB-SD 3.76Å; E377-M417 HydrophobicContact CG-CG 3.92Å; E377-M417 HydrophobicContact CG-SD 4.2Å; S380-M417 VanDerWaalsContact CB-CE 3.44Å; L384-M417 HydrophobicContact CD1-CE 4.27Å; A413-M417 WeakPolarHBondContact O-CB 3.23Å; A413-M417 PolarHBondContact O-N 3.29Å; F414-M417 HydrophobicContact CD1-CE 3.41Å; F414-M417 VanDerWaalsContact CD1-CE 3.41Å; F414-M417 HydrophobicContact CE1-CE 3.62Å; F414-M417 PolarHBondContact O-N 3.39Å; M415-M417 VanDerWaalsContact C-N 3.31Å
418	N	90.3	Very high	93.3	Very high	33 Å²	33	61.9 Å²	61.9	18%	0.176	33%	0.328	C	S	.	.			trans	-150.6	81.1	178.7	-169.4	-24	0	0	0	111.1	L384 F414 T420 M421 F422	L384-N418 HydrophobicContact CD1-CB 4.24Å; F414-N418 PolarHBondContact O-N 3.11Å; F414-N418 VanDerWaalsContact O-N 3.1Å; N418-T420 VanDerWaalsContact C-N 3.33Å; N418-T420 PolarHBondContact O-N 3.08Å; N418-M421 HydrophobicContact CB-CB 4.34Å; N418-M421 PolarHBondContact O-N 3.24Å; N418-M421 WeakPolarHBondContact OD1-CB 3.47Å; N418-M421 PolarHBondContact OD1-N 3.01Å; N418-M421 VanDerWaalsContact OD1-N 3.09Å; N418-F422 WeakPolarHBondContact O-CB 3.39Å; N418-F422 PolarHBondContact O-N 3.34Å
419	S	92.9	Very high	93.1	Very high	65 Å²	65	57.7 Å²	57.7	46%	0.455	31%	0.312	S	S	.	.	H	α-helix	trans	-59.2	-41.4	-175.8	62.1	0	0	0	0	113	M415 F422 D423	M415-S419 VanDerWaalsContact O-CA 3.3Å; M415-S419 WeakPolarHBondContact O-CA 2.92Å; M415-S419 WeakPolarHBondContact O-CB 3.41Å; M415-S419 PolarHBondContact O-N 3.47Å; S419-F422 WeakPolarHBondContact O-CB 3.47Å; S419-F422 PolarHBondContact O-N 3.1Å; S419-D423 PolarHBondContact O-N 3.12Å
420	T	93	Very high	92.8	Very high	88 Å²	88	58.1 Å²	58.1	54%	0.54	31%	0.309	S	S	.	.	H	α-helix	trans	-62.5	-50	-178.2	-51.5	0	0	0	0	111.2	N418 F422 D423 E424	N418-T420 VanDerWaalsContact C-N 3.33Å; N418-T420 PolarHBondContact O-N 3.08Å; T420-F422 VanDerWaalsContact C-N 3.31Å; T420-F422 PolarHBondContact O-N 3.45Å; T420-D423 PolarHBondContact O-N 2.95Å; T420-E424 WeakPolarHBondContact O-CG 3.33Å; T420-E424 PolarHBondContact O-N 3.32Å; T420-E424 VanDerWaalsContact O-N 3.1Å
421	M	92.3	Very high	92.5	Very high	34 Å²	34	61.2 Å²	61.2	17%	0.167	33%	0.331	C	S	.	.	H	α-helix	trans	-66.2	-36.4	178.4	-176.6	172.3	-73.2	0	0	111.8	N381 L384 P385 N418 D423 E424 L425	N381-M421 HydrophobicContact CB-CE 4.1Å; N381-M421 VanDerWaalsContact OD1-CE 3.26Å; N381-M421 WeakPolarHBondContact OD1-CE 3.4Å; L384-M421 HydrophobicContact CB-SD 4.26Å; L384-M421 HydrophobicContact CD2-CG 4.21Å; P385-M421 HydrophobicContact CG-SD 3.98Å; N418-M421 HydrophobicContact CB-CB 4.34Å; N418-M421 PolarHBondContact O-N 3.24Å; N418-M421 WeakPolarHBondContact OD1-CB 3.47Å; N418-M421 PolarHBondContact OD1-N 3.01Å; N418-M421 VanDerWaalsContact OD1-N 3.09Å; M421-D423 VanDerWaalsContact C-N 3.34Å; M421-D423 PolarHBondContact O-N 2.75Å; M421-E424 PolarHBondContact O-N 2.97Å; M421-L425 HydrophobicContact CG-CD1 3.85Å; M421-L425 HydrophobicContact CG-CG 4.34Å; M421-L425 WeakPolarHBondContact O-CB 3.47Å; M421-L425 WeakPolarHBondContact O-CG 3.35Å; M421-L425 PolarHBondContact O-N 3.39Å
422	F	93.2	Very high	92.3	Very high	22 Å²	22	63.5 Å²	63.5	10%	0.096	34%	0.343	C	S	.	.	H	α-helix	trans	-60.5	-43.3	176.7	-171.7	-85.7	0	0	0	112	F388 L411 F414 M415 N418 S419 T420 T426	F388-F422 HydrophobicContact CD2-CD2 4.19Å; F388-F422 HydrophobicContact CD2-CE2 4.13Å; F388-F422 AromaticContact CE2-CD2 3.95Å; F388-F422 HydrophobicContact CE2-CD2 3.95Å; F388-F422 HydrophobicContact CE2-CE1 4.29Å; F388-F422 AromaticContact CE2-CE2 3.73Å; F388-F422 HydrophobicContact CE2-CE2 3.73Å; F388-F422 HydrophobicContact CE2-CG 4.34Å; F388-F422 AromaticContact CE2-CZ 3.91Å; F388-F422 HydrophobicContact CE2-CZ 3.91Å; L411-F422 HydrophobicContact CB-CE2 4.47Å; L411-F422 HydrophobicContact CB-CZ 4.48Å; L411-F422 HydrophobicContact CD2-CE2 3.97Å; L411-F422 HydrophobicContact CD2-CZ 4.22Å; L411-F422 WeakPolarHBondContact O-CE2 3.26Å; F414-F422 HydrophobicContact CB-CD2 4.11Å; F414-F422 HydrophobicContact CB-CE2 4.29Å; M415-F422 HydrophobicContact CB-CD1 4.13Å; M415-F422 HydrophobicContact CB-CD2 4.05Å; M415-F422 HydrophobicContact CB-CE1 4.27Å; M415-F422 HydrophobicContact CB-CE2 4.18Å; M415-F422 HydrophobicContact CB-CG 4.01Å; M415-F422 HydrophobicContact CB-CZ 4.29Å; M415-F422 HydrophobicContact CG-CD1 4.04Å; M415-F422 HydrophobicContact CG-CE1 4.33Å; M415-F422 HydrophobicContact CG-CG 4.28Å; M415-F422 HydrophobicContact SD-CE1 4.45Å; N418-F422 WeakPolarHBondContact O-CB 3.39Å; N418-F422 PolarHBondContact O-N 3.34Å; S419-F422 WeakPolarHBondContact O-CB 3.47Å; S419-F422 PolarHBondContact O-N 3.1Å; T420-F422 VanDerWaalsContact C-N 3.31Å; T420-F422 PolarHBondContact O-N 3.45Å; F422-T426 WeakPolarHBondContact O-CB 3.44Å; F422-T426 PolarHBondContact O-N 3.25Å; F422-T426 PolarHBondContact O-OG1 3.39Å
423	D	93.2	Very high	92	Very high	103 Å²	103	62.1 Å²	62.1	55%	0.551	33%	0.334	S	S	*	.	H	α-helix	trans	-66.8	-43.4	177.1	-75.7	-24.3	0	0	0	112.1	S419 T420 M421 L425 T426 A427	S419-D423 PolarHBondContact O-N 3.12Å; T420-D423 PolarHBondContact O-N 2.95Å; M421-D423 VanDerWaalsContact C-N 3.34Å; M421-D423 PolarHBondContact O-N 2.75Å; D423-L425 PolarHBondContact O-N 2.98Å; D423-T426 WeakPolarHBondContact O-CB 3.36Å; D423-T426 PolarHBondContact O-N 3.24Å; D423-A427 PolarHBondContact O-N 3.46Å
424	E	94	Very high	91.8	Very high	117 Å²	117	67.6 Å²	67.6	55%	0.547	36%	0.356	S	S	.	.	H	α-helix	trans	-59.4	-44.5	176	-73.7	177.5	-177.6	0	0	112.3	T420 M421 A427 T428	T420-E424 WeakPolarHBondContact O-CG 3.33Å; T420-E424 PolarHBondContact O-N 3.32Å; T420-E424 VanDerWaalsContact O-N 3.1Å; M421-E424 PolarHBondContact O-N 2.97Å; E424-A427 PolarHBondContact O-N 2.83Å; E424-T428 WeakPolarHBondContact O-CB 3.37Å; E424-T428 PolarHBondContact O-N 3.11Å; E424-T428 PolarHBondContact O-OG1 3.35Å
425	L	93.9	Very high	91.7	Very high	32 Å²	32	73.9 Å²	73.9	17%	0.168	38%	0.379	C	S	.	.	H	α-helix	trans	-70.3	-34.1	177.6	-70.5	167.2	0	0	0	112.1	L384 P385 F388 M421 D423 A427 T428 Y429	L384-L425 HydrophobicContact CD2-CD1 3.09Å; L384-L425 HydrophobicContact CD2-CG 4.49Å; L384-L425 HydrophobicContact CG-CD1 4.46Å; P385-L425 HydrophobicContact CB-CD1 4.31Å; P385-L425 HydrophobicContact CB-CD2 4.09Å; P385-L425 HydrophobicContact CG-CD1 4.14Å; P385-L425 HydrophobicContact CG-CD2 4.43Å; F388-L425 HydrophobicContact CB-CB 4.49Å; F388-L425 HydrophobicContact CB-CD1 4.13Å; F388-L425 HydrophobicContact CD1-CB 3.86Å; F388-L425 HydrophobicContact CD2-CB 4.08Å; F388-L425 HydrophobicContact CD2-CD1 4.48Å; F388-L425 HydrophobicContact CE1-CB 4.13Å; F388-L425 WeakPolarHBondContact CE1-O 3.11Å; F388-L425 HydrophobicContact CE2-CB 4.32Å; F388-L425 HydrophobicContact CG-CB 3.87Å; F388-L425 HydrophobicContact CG-CD1 4.28Å; F388-L425 HydrophobicContact CZ-CB 4.36Å; M421-L425 HydrophobicContact CG-CD1 3.85Å; M421-L425 HydrophobicContact CG-CG 4.34Å; M421-L425 WeakPolarHBondContact O-CB 3.47Å; M421-L425 WeakPolarHBondContact O-CG 3.35Å; M421-L425 PolarHBondContact O-N 3.39Å; D423-L425 PolarHBondContact O-N 2.98Å; L425-A427 VanDerWaalsContact C-N 3.33Å; L425-A427 PolarHBondContact O-N 3.09Å; L425-T428 PolarHBondContact O-N 3.49Å; L425-Y429 WeakPolarHBondContact O-CB 3.43Å; L425-Y429 PolarHBondContact O-N 3.23Å
426	T	92.3	Very high	91.5	Very high	19 Å²	19	74.4 Å²	74.4	12%	0.117	38%	0.38	C	S	.	.	H	α-helix	trans	-61.3	-43.7	172.7	-61.3	0	0	0	0	111.2	F388 F422 D423 K430	F388-T426 WeakPolarHBondContact CZ-OG1 3.45Å; F422-T426 WeakPolarHBondContact O-CB 3.44Å; F422-T426 PolarHBondContact O-N 3.25Å; F422-T426 PolarHBondContact O-OG1 3.39Å; D423-T426 WeakPolarHBondContact O-CB 3.36Å; D423-T426 PolarHBondContact O-N 3.24Å; T426-K430 WeakPolarHBondContact O-CG 3.36Å; T426-K430 PolarHBondContact O-N 2.81Å
427	A	92.3	Very high	91.3	Very high	61 Å²	61	73.4 Å²	73.4	50%	0.504	37%	0.374	S	S	.	.	H	α-helix	trans	-65.3	-46.9	176.2	0	0	0	0	0	111.6	D423 E424 L425 K430 S431	D423-A427 PolarHBondContact O-N 3.46Å; E424-A427 PolarHBondContact O-N 2.83Å; L425-A427 VanDerWaalsContact C-N 3.33Å; L425-A427 PolarHBondContact O-N 3.09Å; A427-K430 PolarHBondContact O-N 2.94Å; A427-S431 PolarHBondContact O-N 3.46Å; A427-S431 VanDerWaalsContact O-N 3.09Å
428	T	92.4	Very high	91.4	Very high	73 Å²	73	78 Å²	78	45%	0.448	39%	0.393	S	S	.	.	H	α-helix	trans	-61.5	-46.1	179.3	-56.6	0	0	0	0	111.5	E424 L425 K430 S431 D432	E424-T428 WeakPolarHBondContact O-CB 3.37Å; E424-T428 PolarHBondContact O-N 3.11Å; E424-T428 PolarHBondContact O-OG1 3.35Å; L425-T428 PolarHBondContact O-N 3.49Å; T428-K430 VanDerWaalsContact C-N 3.34Å; T428-K430 PolarHBondContact O-N 3.09Å; T428-S431 WeakPolarHBondContact O-CB 3.42Å; T428-S431 PolarHBondContact O-N 2.83Å; T428-S431 VanDerWaalsContact O-N 3.16Å; T428-D432 WeakPolarHBondContact O-CB 3.18Å; T428-D432 PolarHBondContact O-N 3.16Å
429	Y	90.3	Very high	91.6	Very high	38 Å²	38	80.6 Å²	80.6	15%	0.149	40%	0.403	C	S	.	.	H	α-helix	trans	-60.8	-40.8	178.4	-177.9	-87	0	0	0	112.6	F388 Y392 L425 D432 R433	F388-Y429 HydrophobicContact CE1-CD2 4.48Å; F388-Y429 HydrophobicContact CE1-CG 4.17Å; Y392-Y429 AromaticContact CD1-CD1 3.59Å; Y392-Y429 HydrophobicContact CD1-CD1 3.59Å; Y392-Y429 AromaticContact CD1-CE1 3.38Å; Y392-Y429 HydrophobicContact CD1-CE1 3.38Å; Y392-Y429 HydrophobicContact CD1-CG 4.36Å; Y392-Y429 AromaticContact CD1-CZ 3.98Å; Y392-Y429 AromaticContact CE1-CD1 3.87Å; Y392-Y429 HydrophobicContact CE1-CD1 3.87Å; Y392-Y429 AromaticContact CE1-CE1 3.84Å; Y392-Y429 HydrophobicContact CE1-CE1 3.84Å; Y392-Y429 HydrophobicContact CG-CE1 4.47Å; L425-Y429 WeakPolarHBondContact O-CB 3.43Å; L425-Y429 PolarHBondContact O-N 3.23Å; Y429-D432 PolarHBondContact O-N 3.49Å; Y429-R433 WeakPolarHBondContact O-CB 3.48Å; Y429-R433 PolarHBondContact O-N 2.92Å
430	K	88.7	Confident	91.5	Very high	116 Å²	116	83 Å²	83	50%	0.504	41%	0.407	S	S	.	.	H	α-helix	trans	-63.3	-43.9	175.5	-74.5	173.8	-177.2	173.2	0	111.3	T426 A427 T428 Q434	T426-K430 WeakPolarHBondContact O-CG 3.36Å; T426-K430 PolarHBondContact O-N 2.81Å; A427-K430 PolarHBondContact O-N 2.94Å; T428-K430 VanDerWaalsContact C-N 3.34Å; T428-K430 PolarHBondContact O-N 3.09Å; K430-Q434 WeakPolarHBondContact O-CG 3.34Å; K430-Q434 PolarHBondContact O-N 3.33Å; K430-Q434 VanDerWaalsContact O-N 3.11Å
431	S	90.9	Very high	91.5	Very high	71 Å²	71	85.1 Å²	85.1	50%	0.497	41%	0.409	S	S	.	.	H	α-helix	trans	-62.4	-47.1	176.6	-175.4	0	0	0	0	111.7	A427 T428 R433 Q434 R435	A427-S431 PolarHBondContact O-N 3.46Å; A427-S431 VanDerWaalsContact O-N 3.09Å; T428-S431 WeakPolarHBondContact O-CB 3.42Å; T428-S431 PolarHBondContact O-N 2.83Å; T428-S431 VanDerWaalsContact O-N 3.16Å; S431-R433 PolarHBondContact O-N 3.46Å; S431-Q434 WeakPolarHBondContact O-CB 3.48Å; S431-Q434 PolarHBondContact O-N 3.1Å; S431-R435 PolarHBondContact O-N 2.92Å
432	D	90.7	Very high	91.6	Very high	60 Å²	60	88 Å²	88	32%	0.321	42%	0.422	S	S	.	.	H	α-helix	trans	-62.9	-43	178.7	-78.4	-22.6	0	0	0	112.3	T428 Y429 Q434 R435 E436	T428-D432 WeakPolarHBondContact O-CB 3.18Å; T428-D432 PolarHBondContact O-N 3.16Å; Y429-D432 PolarHBondContact O-N 3.49Å; D432-Q434 VanDerWaalsContact C-N 3.3Å; D432-Q434 PolarHBondContact O-N 3.17Å; D432-R435 WeakPolarHBondContact O-CB 3.48Å; D432-R435 PolarHBondContact O-N 3.39Å; D432-R435 VanDerWaalsContact O-N 3.17Å; D432-R435 IonicContact OD1-CZ 2.78Å; D432-R435 VanDerWaalsContact OD1-CZ 3.31Å; D432-R435 IonicContact OD1-NE 3.45Å; D432-R435 IonicContact OD1-NH2 3.59Å; D432-R435 PolarHBondContact OD1-NH2 3.19Å; D432-E436 WeakPolarHBondContact O-CG 3.33Å; D432-E436 PolarHBondContact O-N 3.37Å
433	R	86.8	Confident	91.6	Very high	88 Å²	88	94.4 Å²	94.4	33%	0.332	45%	0.445	S	S	.	.	H	α-helix	trans	-63.5	-36	176.2	-167.6	176.4	-175.3	174.5	6.7	112	E397 Y429 S431 K437	E397-R433 IonicContact OE1-CZ 3.31Å; E397-R433 IonicContact OE1-NH1 2.88Å; E397-R433 IonicContact OE1-NH2 2.65Å; E397-R433 PolarHBondContact OE1-NH2 2.96Å; Y429-R433 WeakPolarHBondContact O-CB 3.48Å; Y429-R433 PolarHBondContact O-N 2.92Å; S431-R433 PolarHBondContact O-N 3.46Å; R433-K437 WeakPolarHBondContact O-CB 3.49Å; R433-K437 WeakPolarHBondContact O-CG 3.48Å; R433-K437 PolarHBondContact O-N 2.65Å; R433-K437 VanDerWaalsContact O-N 3.1Å
434	Q	89.4	Confident	91.6	Very high	141 Å²	141	94.4 Å²	94.4	66%	0.659	44%	0.442	S	S	*	.	H	α-helix	trans	-67.7	-41.4	173.6	-73.5	178.2	-1.2	0	0	111.6	K430 S431 D432 K437 K438	K430-Q434 WeakPolarHBondContact O-CG 3.34Å; K430-Q434 PolarHBondContact O-N 3.33Å; K430-Q434 VanDerWaalsContact O-N 3.11Å; S431-Q434 WeakPolarHBondContact O-CB 3.48Å; S431-Q434 PolarHBondContact O-N 3.1Å; D432-Q434 VanDerWaalsContact C-N 3.3Å; D432-Q434 PolarHBondContact O-N 3.17Å; Q434-K437 PolarHBondContact O-N 2.9Å; Q434-K438 PolarHBondContact O-N 3.41Å
435	R	91.8	Very high	91.7	Very high	137 Å²	137	94 Å²	94	52%	0.517	44%	0.44	S	S	.	.	H	α-helix	trans	-63.7	-43.5	176.6	-176.7	171.9	63.4	178.8	-0.9	112.2	S431 D432 K438 K439	S431-R435 PolarHBondContact O-N 2.92Å; D432-R435 WeakPolarHBondContact O-CB 3.48Å; D432-R435 PolarHBondContact O-N 3.39Å; D432-R435 VanDerWaalsContact O-N 3.17Å; D432-R435 IonicContact OD1-CZ 2.78Å; D432-R435 VanDerWaalsContact OD1-CZ 3.31Å; D432-R435 IonicContact OD1-NE 3.45Å; D432-R435 IonicContact OD1-NH2 3.59Å; D432-R435 PolarHBondContact OD1-NH2 3.19Å; R435-K438 WeakPolarHBondContact O-CB 3.49Å; R435-K438 PolarHBondContact O-N 3Å; R435-K439 WeakPolarHBondContact O-CG 3.4Å; R435-K439 PolarHBondContact O-N 3.49Å
436	E	89.3	Confident	91.7	Very high	93 Å²	93	98.1 Å²	98.1	44%	0.435	46%	0.462	S	S	.	.	H	α-helix	trans	-66.1	-42.7	176.9	-71.4	-55.6	123.2	0	0	111.8	D432 K438 K439 E440	D432-E436 WeakPolarHBondContact O-CG 3.33Å; D432-E436 PolarHBondContact O-N 3.37Å; E436-K438 PolarHBondContact O-N 3.23Å; E436-K439 PolarHBondContact O-N 2.85Å; E436-K439 IonicContact OE1-NZ 3.66Å; E436-K439 PolarHBondContact OE1-NZ 2.78Å; E436-E440 WeakPolarHBondContact O-CB 3.45Å; E436-E440 PolarHBondContact O-N 3.49Å
437	K	89.5	Confident	91.7	Very high	114 Å²	114	104.6 Å²	104.6	50%	0.496	48%	0.484	S	S	.	.	H	α-helix	trans	-58.8	-35.6	171.8	-76.8	-177.9	177.6	-170.2	0	112.7	R433 Q434 K441	R433-K437 WeakPolarHBondContact O-CB 3.49Å; R433-K437 WeakPolarHBondContact O-CG 3.48Å; R433-K437 PolarHBondContact O-N 2.65Å; R433-K437 VanDerWaalsContact O-N 3.1Å; Q434-K437 PolarHBondContact O-N 2.9Å; K437-K441 WeakPolarHBondContact O-CG 3.45Å; K437-K441 PolarHBondContact O-N 3.26Å; K437-K441 VanDerWaalsContact O-N 3.17Å
438	K	93.2	Very high	91.7	Very high	134 Å²	134	107.6 Å²	107.6	58%	0.583	49%	0.486	S	S	*	.	H	α-helix	trans	-68.1	-46.7	175.4	-169.5	-172.3	179.6	-161.7	0	111.2	Q434 R435 E436 E440 K441 E442	Q434-K438 PolarHBondContact O-N 3.41Å; R435-K438 WeakPolarHBondContact O-CB 3.49Å; R435-K438 PolarHBondContact O-N 3Å; E436-K438 PolarHBondContact O-N 3.23Å; K438-E440 VanDerWaalsContact C-N 3.29Å; K438-E440 PolarHBondContact O-N 3.29Å; K438-K441 PolarHBondContact O-N 3.17Å; K438-E442 WeakPolarHBondContact CE-OE1 3.44Å; K438-E442 IonicContact NZ-OE1 3.65Å; K438-E442 WeakPolarHBondContact O-CG 3.38Å; K438-E442 PolarHBondContact O-N 3.17Å
439	K	93.3	Very high	91.7	Very high	87 Å²	87	110.1 Å²	110.1	38%	0.378	49%	0.491	S	S	.	.	H	α-helix	trans	-61.3	-36.8	176.1	-71.4	178.9	-173.5	166	0	112.7	R435 E436 E442 R443	R435-K439 WeakPolarHBondContact O-CG 3.4Å; R435-K439 PolarHBondContact O-N 3.49Å; E436-K439 PolarHBondContact O-N 2.85Å; E436-K439 IonicContact OE1-NZ 3.66Å; E436-K439 PolarHBondContact OE1-NZ 2.78Å; K439-E442 PolarHBondContact O-N 2.87Å; K439-R443 WeakPolarHBondContact O-CB 3.37Å; K439-R443 PolarHBondContact O-N 2.95Å
440	E	91.1	Very high	91.7	Very high	115 Å²	115	112.8 Å²	112.8	54%	0.537	51%	0.507	S	S	.	.	H	α-helix	trans	-63.4	-47.3	175.5	-172.9	171.1	-147.6	0	0	110.9	E436 K438 E442 R443 E444	E436-E440 WeakPolarHBondContact O-CB 3.45Å; E436-E440 PolarHBondContact O-N 3.49Å; K438-E440 VanDerWaalsContact C-N 3.29Å; K438-E440 PolarHBondContact O-N 3.29Å; E440-E442 PolarHBondContact O-N 3.18Å; E440-R443 WeakPolarHBondContact O-CB 3.34Å; E440-R443 PolarHBondContact O-N 2.97Å; E440-R443 VanDerWaalsContact O-N 3.17Å; E440-E444 WeakPolarHBondContact O-CG 3.14Å; E440-E444 PolarHBondContact O-N 2.94Å
441	K	92.9	Very high	91.7	Very high	133 Å²	133	112.8 Å²	112.8	58%	0.578	51%	0.509	S	S	*	.	H	α-helix	trans	-60.2	-45.3	173.1	-72	179.6	178.4	-169.9	0	113	K437 K438 R443 E444 E445	K437-K441 WeakPolarHBondContact O-CG 3.45Å; K437-K441 PolarHBondContact O-N 3.26Å; K437-K441 VanDerWaalsContact O-N 3.17Å; K438-K441 PolarHBondContact O-N 3.17Å; K441-R443 PolarHBondContact O-N 3.49Å; K441-E444 PolarHBondContact O-N 3.35Å; K441-E445 WeakPolarHBondContact O-CG 3.37Å; K441-E445 PolarHBondContact O-N 3.01Å
442	E	94.5	Very high	91.7	Very high	95 Å²	95	114 Å²	114	44%	0.444	51%	0.509	S	S	.	.	H	α-helix	trans	-59.6	-37.2	176.3	-73.5	170.5	-176.9	0	0	111.3	K438 K439 E440 L446	K438-E442 WeakPolarHBondContact CE-OE1 3.44Å; K438-E442 IonicContact NZ-OE1 3.65Å; K438-E442 WeakPolarHBondContact O-CG 3.38Å; K438-E442 PolarHBondContact O-N 3.17Å; K439-E442 PolarHBondContact O-N 2.87Å; E440-E442 PolarHBondContact O-N 3.18Å; E442-L446 WeakPolarHBondContact O-CB 3.48Å; E442-L446 PolarHBondContact O-N 2.9Å
443	R	93.8	Very high	91.5	Very high	156 Å²	156	116.2 Å²	116.2	59%	0.589	52%	0.521	S	S	*	.	H	α-helix	trans	-69.3	-44.7	175.7	-167.9	-174.6	-53.8	-159.5	3.7	112	K439 E440 K441 E445 L446 W447	K439-R443 WeakPolarHBondContact O-CB 3.37Å; K439-R443 PolarHBondContact O-N 2.95Å; E440-R443 WeakPolarHBondContact O-CB 3.34Å; E440-R443 PolarHBondContact O-N 2.97Å; E440-R443 VanDerWaalsContact O-N 3.17Å; K441-R443 PolarHBondContact O-N 3.49Å; R443-E445 VanDerWaalsContact C-N 3.32Å; R443-E445 PolarHBondContact O-N 3.22Å; R443-L446 WeakPolarHBondContact O-CB 3.48Å; R443-L446 PolarHBondContact O-N 3.49Å; R443-W447 PolarHBondContact O-N 3.34Å
444	E	93.5	Very high	91.3	Very high	103 Å²	103	118.6 Å²	118.6	48%	0.481	54%	0.536	S	S	.	.	H	α-helix	trans	-59.9	-42.4	174.7	-73.7	-180	-179.9	0	0	111.8	E440 K441 L446 W447 K448	E440-E444 WeakPolarHBondContact O-CG 3.14Å; E440-E444 PolarHBondContact O-N 2.94Å; K441-E444 PolarHBondContact O-N 3.35Å; E444-L446 VanDerWaalsContact C-N 3.33Å; E444-L446 PolarHBondContact O-N 3.25Å; E444-W447 PolarHBondContact O-N 2.9Å; E444-K448 WeakPolarHBondContact O-CG 3.3Å; E444-K448 PolarHBondContact O-N 3.34Å
445	E	94.4	Very high	90.7	Very high	108 Å²	108	117.8 Å²	117.8	51%	0.505	54%	0.535	S	S	.	.	H	α-helix	trans	-64	-38.2	175.2	-73.7	176.7	-167.2	0	0	112.2	K441 R443 K449	K441-E445 WeakPolarHBondContact O-CG 3.37Å; K441-E445 PolarHBondContact O-N 3.01Å; R443-E445 VanDerWaalsContact C-N 3.32Å; R443-E445 PolarHBondContact O-N 3.22Å; E445-K449 WeakPolarHBondContact O-CB 3.39Å; E445-K449 VanDerWaalsContact O-CG 3.29Å; E445-K449 WeakPolarHBondContact O-CG 3.48Å; E445-K449 PolarHBondContact O-N 3.02Å
446	L	93.7	Very high	90.1	Very high	119 Å²	119	117.6 Å²	117.6	62%	0.623	54%	0.538	S	S	*	.	H	α-helix	trans	-65.1	-42.9	175.5	-167	74.5	0	0	0	111.5	E442 R443 E444 K449 L450	E442-L446 WeakPolarHBondContact O-CB 3.48Å; E442-L446 PolarHBondContact O-N 2.9Å; R443-L446 WeakPolarHBondContact O-CB 3.48Å; R443-L446 PolarHBondContact O-N 3.49Å; E444-L446 VanDerWaalsContact C-N 3.33Å; E444-L446 PolarHBondContact O-N 3.25Å; L446-K449 PolarHBondContact O-N 2.95Å; L446-L450 PolarHBondContact O-N 2.92Å
447	W	92.4	Very high	89.3	Confident	154 Å²	154	122.5 Å²	122.5	58%	0.583	55%	0.553	S	S	*	*	H	α-helix	trans	-63	-45.6	175.2	-79.4	115.1	0	0	0	112.1	R443 E444 K449 L450 E451	R443-W447 PolarHBondContact O-N 3.34Å; E444-W447 PolarHBondContact O-N 2.9Å; W447-K449 VanDerWaalsContact C-N 3.32Å; W447-K449 PolarHBondContact O-N 3.02Å; W447-L450 HydrophobicContact CE3-CD2 3.89Å; W447-L450 HydrophobicContact CZ3-CD2 3.74Å; W447-L450 WeakPolarHBondContact O-CA 3.29Å; W447-L450 VanDerWaalsContact O-CB 3.3Å; W447-L450 WeakPolarHBondContact O-CB 3.49Å; W447-L450 PolarHBondContact O-N 3.39Å; W447-E451 PolarHBondContact O-N 2.9Å
448	K	93.1	Very high	88.2	Confident	124 Å²	124	118.6 Å²	118.6	54%	0.539	55%	0.545	S	S	.	.	H	α-helix	trans	-58.7	-42.6	175	-74.6	175.8	-179.6	173.2	0	112.3	E444 L450 E451 D452	E444-K448 WeakPolarHBondContact O-CG 3.3Å; E444-K448 PolarHBondContact O-N 3.34Å; K448-L450 VanDerWaalsContact C-N 3.28Å; K448-L450 PolarHBondContact O-N 3Å; K448-E451 PolarHBondContact O-N 3.38Å; K448-D452 WeakPolarHBondContact O-CB 3.49Å; K448-D452 PolarHBondContact O-N 3.38Å
449	K	92.2	Very high	86.7	Confident	127 Å²	127	118.1 Å²	118.1	55%	0.552	55%	0.548	S	S	*	.	H	α-helix	trans	-62.5	-35.1	174.5	-74.9	171.2	-176	169	0	112.2	E445 L446 W447 L453	E445-K449 WeakPolarHBondContact O-CB 3.39Å; E445-K449 VanDerWaalsContact O-CG 3.29Å; E445-K449 WeakPolarHBondContact O-CG 3.48Å; E445-K449 PolarHBondContact O-N 3.02Å; L446-K449 PolarHBondContact O-N 2.95Å; W447-K449 VanDerWaalsContact C-N 3.32Å; W447-K449 PolarHBondContact O-N 3.02Å; K449-L453 WeakPolarHBondContact O-CB 3.46Å; K449-L453 VanDerWaalsContact O-CG 3.25Å; K449-L453 WeakPolarHBondContact O-CG 3.25Å; K449-L453 PolarHBondContact O-N 3.11Å; K449-L453 VanDerWaalsContact O-N 3.11Å
450	L	91	Very high	85.1	Confident	94 Å²	94	123.6 Å²	123.6	49%	0.492	57%	0.566	S	S	.	*	H	α-helix	trans	-67.9	-46.3	176.5	-162.9	81.7	0	0	0	111	L446 W447 K448 D452 L453 E454	L446-L450 PolarHBondContact O-N 2.92Å; W447-L450 HydrophobicContact CE3-CD2 3.89Å; W447-L450 HydrophobicContact CZ3-CD2 3.74Å; W447-L450 WeakPolarHBondContact O-CA 3.29Å; W447-L450 VanDerWaalsContact O-CB 3.3Å; W447-L450 WeakPolarHBondContact O-CB 3.49Å; W447-L450 PolarHBondContact O-N 3.39Å; K448-L450 VanDerWaalsContact C-N 3.28Å; K448-L450 PolarHBondContact O-N 3Å; L450-D452 VanDerWaalsContact C-N 3.35Å; L450-D452 PolarHBondContact O-N 3.17Å; L450-L453 PolarHBondContact O-N 3.48Å; L450-L453 VanDerWaalsContact O-N 3.17Å; L450-E454 PolarHBondContact O-N 2.93Å
451	E	89.2	Confident	83.5	Confident	116 Å²	116	128.2 Å²	128.2	54%	0.542	58%	0.579	S	S	.	*	H	α-helix	trans	-59	-44.6	175.3	-71.1	172.9	-178	0	0	111.2	W447 K448 L453 E454 L455	W447-E451 PolarHBondContact O-N 2.9Å; K448-E451 PolarHBondContact O-N 3.38Å; E451-L453 VanDerWaalsContact C-N 3.31Å; E451-L453 PolarHBondContact O-N 3.21Å; E451-E454 PolarHBondContact O-N 3.37Å; E451-L455 PolarHBondContact O-N 2.92Å
452	D	89.6	Confident	81.8	Confident	95 Å²	95	128.6 Å²	128.6	51%	0.508	59%	0.587	S	S	.	*	H	α-helix	trans	-61.3	-37.6	175.8	-75.8	-20.2	0	0	0	112.5	K448 L450 K456	K448-D452 WeakPolarHBondContact O-CB 3.49Å; K448-D452 PolarHBondContact O-N 3.38Å; L450-D452 VanDerWaalsContact C-N 3.35Å; L450-D452 PolarHBondContact O-N 3.17Å; D452-K456 WeakPolarHBondContact O-CB 3.49Å; D452-K456 VanDerWaalsContact O-CG 3.25Å; D452-K456 WeakPolarHBondContact O-CG 3.37Å; D452-K456 PolarHBondContact O-N 3.13Å; D452-K456 VanDerWaalsContact O-N 3.13Å
453	L	87.7	Confident	79.9	Confident	108 Å²	108	127.1 Å²	127.1	57%	0.565	60%	0.598	S	S	*	*	H	α-helix	trans	-72.2	-34.9	176.8	-75.2	171.6	0	0	0	112.1	K449 L450 E451 R457	K449-L453 WeakPolarHBondContact O-CB 3.46Å; K449-L453 VanDerWaalsContact O-CG 3.25Å; K449-L453 WeakPolarHBondContact O-CG 3.25Å; K449-L453 PolarHBondContact O-N 3.11Å; K449-L453 VanDerWaalsContact O-N 3.11Å; L450-L453 PolarHBondContact O-N 3.48Å; L450-L453 VanDerWaalsContact O-N 3.17Å; E451-L453 VanDerWaalsContact C-N 3.31Å; E451-L453 PolarHBondContact O-N 3.21Å; L453-R457 PolarHBondContact O-N 2.84Å
454	E	81.9	Confident	77.8	Confident	138 Å²	138	125.9 Å²	125.9	65%	0.645	60%	0.601	S	S	*	*	H	α-helix	trans	-66.6	-46	173.9	-173.3	169.3	-164	0	0	111.1	L450 E451 K456 R457 G458	L450-E454 PolarHBondContact O-N 2.93Å; E451-E454 PolarHBondContact O-N 3.37Å; E454-K456 VanDerWaalsContact C-N 3.31Å; E454-K456 PolarHBondContact O-N 3.36Å; E454-R457 CarbonylContact O-C 3.58Å; E454-R457 WeakPolarHBondContact O-CA 3.25Å; E454-R457 PolarHBondContact O-N 3.01Å; E454-G458 PolarHBondContact O-N 3.07Å
455	L	76.8	Confident	75.4	Confident	124 Å²	124	128.2 Å²	128.2	65%	0.649	62%	0.615	S	S	*	*	H	α-helix	trans	-58.4	-43.5	175.8	-136.7	96.9	0	0	0	111.4	E451 R457 G458 L459	E451-L455 PolarHBondContact O-N 2.92Å; L455-R457 VanDerWaalsContact C-N 3.29Å; L455-R457 PolarHBondContact O-N 3.32Å; L455-G458 PolarHBondContact O-N 3.4Å; L455-L459 WeakPolarHBondContact O-CD1 3.49Å; L455-L459 WeakPolarHBondContact O-CG 3.46Å; L455-L459 PolarHBondContact O-N 2.99Å
456	K	78.1	Confident	73.3	Confident	133 Å²	133	128.3 Å²	128.3	58%	0.578	63%	0.625	S	S	*	*	H	α-helix	trans	-65.1	-29.5	175.6	-75.4	172	-176.2	171.2	0	113.1	D452 E454 R460	D452-K456 WeakPolarHBondContact O-CB 3.49Å; D452-K456 VanDerWaalsContact O-CG 3.25Å; D452-K456 WeakPolarHBondContact O-CG 3.37Å; D452-K456 PolarHBondContact O-N 3.13Å; D452-K456 VanDerWaalsContact O-N 3.13Å; E454-K456 VanDerWaalsContact C-N 3.31Å; E454-K456 PolarHBondContact O-N 3.36Å; K456-R460 WeakPolarHBondContact O-CG 3.38Å; K456-R460 PolarHBondContact O-N 3.43Å
457	R	72.8	Confident	70.7	Confident	195 Å²	195	132.3 Å²	132.3	74%	0.736	66%	0.655	S	S	*	*	H	α-helix	trans	-78.9	-36.8	174	-83.3	-177.2	166.9	-173.5	-2.2	112.3	L453 E454 L455 R460 R461	L453-R457 PolarHBondContact O-N 2.84Å; E454-R457 CarbonylContact O-C 3.58Å; E454-R457 WeakPolarHBondContact O-CA 3.25Å; E454-R457 PolarHBondContact O-N 3.01Å; L455-R457 VanDerWaalsContact C-N 3.29Å; L455-R457 PolarHBondContact O-N 3.32Å; R457-R460 PolarHBondContact O-N 3.45Å; R457-R461 PolarHBondContact O-N 2.92Å
458	G	67.9	Low	69.6	Low	32 Å²	32	131.3 Å²	131.3	33%	0.33	66%	0.659	S	S	.	*	H	α-helix	trans	-61.3	-48.9	173.5	0	0	0	0	0	111.8	E454 L455 R460 R461 D462	E454-G458 PolarHBondContact O-N 3.07Å; L455-G458 PolarHBondContact O-N 3.4Å; G458-R460 PolarHBondContact O-N 3.12Å; G458-R460 VanDerWaalsContact O-N 3.15Å; G458-R461 PolarHBondContact O-N 3.24Å; G458-D462 PolarHBondContact O-N 3.15Å; G458-D462 VanDerWaalsContact O-N 3.12Å
459	L	60.4	Low	68.4	Low	125 Å²	125	131.6 Å²	131.6	65%	0.654	67%	0.665	S	S	*	*	H	α-helix	trans	-59	-28.8	175.6	-73.6	162.4	0	0	0	113.4	L455	L455-L459 WeakPolarHBondContact O-CD1 3.49Å; L455-L459 WeakPolarHBondContact O-CG 3.46Å; L455-L459 PolarHBondContact O-N 2.99Å
460	R	59.7	Low	67.1	Low	201 Å²	201	131.9 Å²	131.9	76%	0.758	67%	0.671	S	S	*	*	H	α-helix	trans	-78.6	-22.2	174.8	-76.9	-177.8	-178.4	-161.8	0.9	113.7	K456 R457 G458	K456-R460 WeakPolarHBondContact O-CG 3.38Å; K456-R460 PolarHBondContact O-N 3.43Å; R457-R460 PolarHBondContact O-N 3.45Å; G458-R460 PolarHBondContact O-N 3.12Å; G458-R460 VanDerWaalsContact O-N 3.15Å
461	R	58.7	Low	65.7	Low	213 Å²	213	134.1 Å²	134.1	80%	0.804	68%	0.682	S	S	*	*	H	α-helix	trans	-86.2	-34.4	177.9	-80.1	-177.5	172.5	174.9	-2.8	112.3	R457 G458 G463	R457-R461 PolarHBondContact O-N 2.92Å; G458-R461 PolarHBondContact O-N 3.24Å; R461-G463 VanDerWaalsContact C-N 3.27Å; R461-G463 PolarHBondContact O-N 3.5Å
462	D	56	Low	64.2	Low	141 Å²	141	135.3 Å²	135.3	75%	0.754	69%	0.691	S	S	*	*	T	Hydrogen-bonded Turn	trans	-79.3	-11	177.1	-66.4	-22.6	0	0	0	113.3	G458 I464	G458-D462 PolarHBondContact O-N 3.15Å; G458-D462 VanDerWaalsContact O-N 3.12Å; D462-I464 VanDerWaalsContact C-N 3.3Å; D462-I464 PolarHBondContact O-N 3.28Å
463	G	55.5	Low	62.5	Low	64 Å²	64	137.9 Å²	137.9	66%	0.66	70%	0.703	S	S	*	*	T	Hydrogen-bonded Turn	trans	-82.5	6.5	176.2	0	0	0	0	0	115.6	R461	R461-G463 VanDerWaalsContact C-N 3.27Å; R461-G463 PolarHBondContact O-N 3.5Å
464	I	49.3	Very low	60.7	Low	129 Å²	129	140.1 Å²	140.1	66%	0.662	71%	0.713	S	S	*	*			trans	-120.3	76.8	179.4	-49.4	176.1	0	0	0	109.3	D462	D462-I464 VanDerWaalsContact C-N 3.3Å; D462-I464 PolarHBondContact O-N 3.28Å
465	I	42.7	Very low	59.1	Low	152 Å²	152	140.2 Å²	140.2	78%	0.779	72%	0.718	S	S	*	*			trans	-124	95.2	154.4	-53.9	176.5	0	0	0	106.3
466	P	51	Low	57.6	Low	110 Å²	110	141.6 Å²	141.6	71%	0.714	72%	0.723	S	S	*	*			trans	-81.8	116.9	161.1	17.3	-2.1	0	0	0	108
467	T	39.2	Very low	55.7	Low	204 Å²	204	142.4 Å²	142.4	100%	1.252	74%	0.737	S	S	*	*			trans	-60.3	0	153.2	46.1	0	0	0	0	111

Retrieved 467 of 467 residues in 252.9 ms (Link to these results)

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