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Multidrug efflux pump SdrM

Energy-dependent drug efflux pump that increases resistance to antimicrobial agents such as norfloxacin, acriflavine and ethidium bromide.

AlphaFold DB (Q2FW83), UniProt , Accession Q99S97, Species STAAN (Staphylococcus aureus (strain N315)), Gene sdrM, Length 447 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M65.3Low90.1Very high121 Ų12172 Ų7260%0.59634%0.341SS*.  01440-75.7171.167.800108.1I6 V9 F123 L127 I131M1-I6 HydrophobicContact CB-CD1 4.37Å; M1-I6 HydrophobicContact CB-CG1 3.87Å; M1-I6 HydrophobicContact CE-CG1 4.47Å; M1-V9 HydrophobicContact CE-CG2 3.82Å; M1-F123 HydrophobicContact CE-CE1 4.11Å; M1-L127 HydrophobicContact CE-CD2 4.34Å; M1-L127 HydrophobicContact CG-CD1 4.29Å; M1-L127 HydrophobicContact CG-CD2 4.06Å; M1-L127 HydrophobicContact SD-CD1 3.95Å; M1-L127 HydrophobicContact SD-CD2 4.4Å; M1-I131 HydrophobicContact CE-CD1 4.05Å; M1-I131 HydrophobicContact SD-CD1 4.47Å
2R83.9Confident90.6Very high213 Ų21366 Ų6680%0.80431%0.313SS*.  trans-65.7154.5173.2-66.5-178.5-179.9177.10.8109.7K4 S5 I6R2-K4 VanDerWaalsContact C-N 3.3Å; R2-K4 PolarHBondContact O-N 3.16Å; R2-S5 VanDerWaalsContact O-CB 3.24Å; R2-S5 WeakPolarHBondContact O-CB 3.25Å; R2-S5 PolarHBondContact O-N 3.16Å; R2-I6 PolarHBondContact O-N 3.33Å
3L88.2Confident91Very high131 Ų13165.1 Ų65.169%0.68631%0.31SS*.Hα-helixtrans-53.4-45.4-179.2-179.263.5000112.3S5 I6 I7L3-S5 VanDerWaalsContact C-N 3.29Å; L3-S5 PolarHBondContact O-N 3.48Å; L3-I6 PolarHBondContact O-N 2.99Å; L3-I6 VanDerWaalsContact O-N 3.09Å; L3-I7 HydrophobicContact CD1-CD1 4.15Å; L3-I7 HydrophobicContact CD1-CG1 4.37Å; L3-I7 HydrophobicContact CD2-CD1 4.46Å; L3-I7 HydrophobicContact CG-CD1 3.84Å; L3-I7 HydrophobicContact CG-CG1 4.45Å; L3-I7 WeakPolarHBondContact O-CG1 3.35Å; L3-I7 PolarHBondContact O-N 3.44Å
4K89.1Confident91.4Very high100 Ų10063.1 Ų63.144%0.43530%0.302SS..Hα-helixtrans-53.7-44.6176-170.4179.6179.1-174.10112R2 I6 I7 T8 T180 H182R2-K4 VanDerWaalsContact C-N 3.3Å; R2-K4 PolarHBondContact O-N 3.16Å; K4-I6 PolarHBondContact O-N 3.26Å; K4-I7 PolarHBondContact O-N 3.33Å; K4-T8 PolarHBondContact O-N 3.06Å; K4-T8 PolarHBondContact O-OG1 3.16Å; K4-T180 WeakPolarHBondContact CE-O 3.32Å; K4-T180 HydrophobicContact CG-CG2 4.06Å; K4-H182 PolarHBondContact NZ-O 2.83Å
5S91.4Very high91.6Very high28 Ų2858.9 Ų58.920%0.19628%0.282CS..Hα-helixtrans-61.3-42.6177.9-60.90000112.5R2 L3 T8 V9R2-S5 VanDerWaalsContact O-CB 3.24Å; R2-S5 WeakPolarHBondContact O-CB 3.25Å; R2-S5 PolarHBondContact O-N 3.16Å; L3-S5 VanDerWaalsContact C-N 3.29Å; L3-S5 PolarHBondContact O-N 3.48Å; S5-T8 PolarHBondContact O-N 3.12Å; S5-V9 WeakPolarHBondContact O-CG2 3.35Å; S5-V9 PolarHBondContact O-N 2.91Å; S5-V9 VanDerWaalsContact O-N 3.13Å
6I93.2Very high91.7Very high76 Ų7655.4 Ų55.439%0.3927%0.265SS..Hα-helixtrans-64.5-45.4178.1-63.3172.7000109.8M1 R2 L3 K4 T8 V9 I10M1-I6 HydrophobicContact CB-CD1 4.37Å; M1-I6 HydrophobicContact CB-CG1 3.87Å; M1-I6 HydrophobicContact CE-CG1 4.47Å; R2-I6 PolarHBondContact O-N 3.33Å; L3-I6 PolarHBondContact O-N 2.99Å; L3-I6 VanDerWaalsContact O-N 3.09Å; K4-I6 PolarHBondContact O-N 3.26Å; I6-T8 VanDerWaalsContact C-N 3.34Å; I6-T8 PolarHBondContact O-N 3.11Å; I6-V9 WeakPolarHBondContact O-CB 3.23Å; I6-V9 PolarHBondContact O-N 3.23Å; I6-V9 VanDerWaalsContact O-N 3.13Å; I6-I10 HydrophobicContact CG2-CD1 4Å; I6-I10 WeakPolarHBondContact O-CG1 3.41Å; I6-I10 PolarHBondContact O-N 3.36Å
7I95.1Very high91.8Very high32 Ų3253.9 Ų53.916%0.16426%0.257CS..Hα-helixtrans-61.9-41.3178.8-62.9169.2000111.1L3 K4 V9 I10 A11 L176 T180L3-I7 HydrophobicContact CD1-CD1 4.15Å; L3-I7 HydrophobicContact CD1-CG1 4.37Å; L3-I7 HydrophobicContact CD2-CD1 4.46Å; L3-I7 HydrophobicContact CG-CD1 3.84Å; L3-I7 HydrophobicContact CG-CG1 4.45Å; L3-I7 WeakPolarHBondContact O-CG1 3.35Å; L3-I7 PolarHBondContact O-N 3.44Å; K4-I7 PolarHBondContact O-N 3.33Å; I7-V9 VanDerWaalsContact C-N 3.31Å; I7-V9 PolarHBondContact O-N 2.91Å; I7-I10 PolarHBondContact O-N 3.27Å; I7-A11 PolarHBondContact O-N 3.49Å; I7-L176 HydrophobicContact CG2-CB 4.06Å; I7-L176 HydrophobicContact CG2-CD2 3.7Å; I7-L176 HydrophobicContact CG2-CG 4.36Å; I7-T180 HydrophobicContact CB-CG2 3.62Å; I7-T180 HydrophobicContact CG2-CG2 3.27Å
8T95.6Very high91.8Very high4 Ų450.9 Ų50.93%0.02524%0.243CC..Hα-helixtrans-60.2-40.9174.4-57.20000111.9K4 S5 I6 A11 L12 V118 A122 F123 T180 F181K4-T8 PolarHBondContact O-N 3.06Å; K4-T8 PolarHBondContact O-OG1 3.16Å; S5-T8 PolarHBondContact O-N 3.12Å; I6-T8 VanDerWaalsContact C-N 3.34Å; I6-T8 PolarHBondContact O-N 3.11Å; T8-A11 PolarHBondContact O-N 3.25Å; T8-L12 HydrophobicContact CG2-CD1 4.38Å; T8-L12 WeakPolarHBondContact O-CG 3.48Å; T8-L12 PolarHBondContact O-N 3.09Å; T8-V118 HydrophobicContact CG2-CG1 3.95Å; T8-A122 HydrophobicContact CG2-CB 3.99Å; T8-F123 HydrophobicContact CG2-CE2 4.16Å; T8-F123 HydrophobicContact CG2-CZ 4Å; T8-T180 VanDerWaalsContact OG1-CB 3.32Å; T8-T180 WeakPolarHBondContact OG1-CB 3.42Å; T8-F181 HydrophobicContact CG2-CE1 4.1Å
9V95.8Very high91.6Very high12 Ų1248.5 Ų48.57%0.07323%0.232CC..Hα-helixtrans-65.2-43.7176.41750000111M1 S5 I6 I7 A11 L12 I13 F123 I131 I134M1-V9 HydrophobicContact CE-CG2 3.82Å; S5-V9 WeakPolarHBondContact O-CG2 3.35Å; S5-V9 PolarHBondContact O-N 2.91Å; S5-V9 VanDerWaalsContact O-N 3.13Å; I6-V9 WeakPolarHBondContact O-CB 3.23Å; I6-V9 PolarHBondContact O-N 3.23Å; I6-V9 VanDerWaalsContact O-N 3.13Å; I7-V9 VanDerWaalsContact C-N 3.31Å; I7-V9 PolarHBondContact O-N 2.91Å; V9-A11 VanDerWaalsContact C-N 3.31Å; V9-A11 PolarHBondContact O-N 3.02Å; V9-L12 PolarHBondContact O-N 3.02Å; V9-I13 HydrophobicContact CG1-CD1 3.83Å; V9-I13 HydrophobicContact CG1-CG1 4.32Å; V9-I13 VanDerWaalsContact O-CG1 3.3Å; V9-I13 WeakPolarHBondContact O-CG1 3.42Å; V9-I13 PolarHBondContact O-N 3.23Å; V9-F123 HydrophobicContact CG2-CE1 4.38Å; V9-F123 HydrophobicContact CG2-CE2 4.12Å; V9-F123 HydrophobicContact CG2-CZ 3.64Å; V9-I131 HydrophobicContact CG1-CD1 4.41Å; V9-I131 HydrophobicContact CG2-CB 4.5Å; V9-I131 HydrophobicContact CG2-CD1 3.45Å; V9-I131 VanDerWaalsContact CG2-CD1 3.45Å; V9-I131 HydrophobicContact CG2-CG1 3.89Å; V9-I131 HydrophobicContact CG2-CG2 3.86Å; V9-I134 HydrophobicContact CG1-CG2 4.44Å
10I96.6Very high91.3Very high75 Ų7546.2 Ų46.239%0.38522%0.221SC..Hα-helixtrans-59.5-45.1176.2-64.1167.7000110I6 I7 L12 I13 L14 L176I6-I10 HydrophobicContact CG2-CD1 4Å; I6-I10 WeakPolarHBondContact O-CG1 3.41Å; I6-I10 PolarHBondContact O-N 3.36Å; I7-I10 PolarHBondContact O-N 3.27Å; I10-L12 VanDerWaalsContact C-N 3.34Å; I10-L12 PolarHBondContact O-N 3.39Å; I10-I13 PolarHBondContact O-N 2.88Å; I10-L14 HydrophobicContact CG2-CD1 4.38Å; I10-L14 HydrophobicContact CG2-CG 4.37Å; I10-L14 WeakPolarHBondContact O-CG 3.43Å; I10-L14 PolarHBondContact O-N 2.84Å; I10-L176 HydrophobicContact CB-CD1 4.24Å; I10-L176 HydrophobicContact CG2-CD1 3.62Å
11A97.1Very high91.2Very high0 Ų044.1 Ų44.10%021%0.211CC..Hα-helixtrans-56.9-46.3175.700000111.9I7 T8 V9 I13 L14 I15 L176 V177 F181I7-A11 PolarHBondContact O-N 3.49Å; T8-A11 PolarHBondContact O-N 3.25Å; V9-A11 VanDerWaalsContact C-N 3.31Å; V9-A11 PolarHBondContact O-N 3.02Å; A11-I13 PolarHBondContact O-N 3.32Å; A11-L14 PolarHBondContact O-N 3.31Å; A11-I15 WeakPolarHBondContact O-CB 3.4Å; A11-I15 WeakPolarHBondContact O-CG1 3.36Å; A11-I15 PolarHBondContact O-N 3.35Å; A11-L176 HydrophobicContact CB-CB 3.84Å; A11-L176 HydrophobicContact CB-CD1 4.39Å; A11-V177 HydrophobicContact CB-CG2 4.48Å; A11-F181 HydrophobicContact CB-CE1 4.18Å
12L96.5Very high92.2Very high0 Ų038.5 Ų38.50%018%0.184CC..Hα-helixtrans-64.5-37.2177.6-69.8171000113.1T8 V9 I10 M16 V118 P119 F123 I131 V135 F181T8-L12 HydrophobicContact CG2-CD1 4.38Å; T8-L12 WeakPolarHBondContact O-CG 3.48Å; T8-L12 PolarHBondContact O-N 3.09Å; V9-L12 PolarHBondContact O-N 3.02Å; I10-L12 VanDerWaalsContact C-N 3.34Å; I10-L12 PolarHBondContact O-N 3.39Å; L12-M16 WeakPolarHBondContact O-CB 3.38Å; L12-M16 PolarHBondContact O-N 3.43Å; L12-V118 HydrophobicContact CD1-CB 4.45Å; L12-V118 HydrophobicContact CD1-CG1 4.02Å; L12-V118 HydrophobicContact CD2-CB 3.84Å; L12-V118 HydrophobicContact CD2-CG1 3.96Å; L12-V118 HydrophobicContact CD2-CG2 4.33Å; L12-V118 HydrophobicContact CG-CG1 4.27Å; L12-P119 HydrophobicContact CD1-CG 4.21Å; L12-F123 HydrophobicContact CD1-CE2 4.47Å; L12-I131 HydrophobicContact CD1-CG2 4.22Å; L12-V135 HydrophobicContact CB-CG2 3.71Å; L12-V135 HydrophobicContact CD1-CG2 4.44Å; L12-F181 HydrophobicContact CD2-CZ 4.29Å
13I95.8Very high91.9Very high54 Ų5430 Ų3028%0.27716%0.157SC..Hα-helixtrans-63.1-49.1174.7-69.5165.9000109.8V9 I10 A11 I15 M16 F17 I134 V138V9-I13 HydrophobicContact CG1-CD1 3.83Å; V9-I13 HydrophobicContact CG1-CG1 4.32Å; V9-I13 VanDerWaalsContact O-CG1 3.3Å; V9-I13 WeakPolarHBondContact O-CG1 3.42Å; V9-I13 PolarHBondContact O-N 3.23Å; I10-I13 PolarHBondContact O-N 2.88Å; A11-I13 PolarHBondContact O-N 3.32Å; I13-I15 PolarHBondContact O-N 2.92Å; I13-M16 PolarHBondContact O-N 3.01Å; I13-F17 WeakPolarHBondContact O-CB 3.4Å; I13-F17 PolarHBondContact O-N 3.28Å; I13-I134 HydrophobicContact CD1-CG2 3.62Å; I13-I134 HydrophobicContact CG1-CG2 3.84Å; I13-V138 HydrophobicContact CG2-CG2 4.11Å
14L95.9Very high91.5Very high37 Ų3724.7 Ų24.719%0.19413%0.131CC..Hα-helixtrans-62-44.7179.8-64.2-175.5000111.5I10 A11 M16 F17 M18 I169 I172 A173 L176I10-L14 HydrophobicContact CG2-CD1 4.38Å; I10-L14 HydrophobicContact CG2-CG 4.37Å; I10-L14 WeakPolarHBondContact O-CG 3.43Å; I10-L14 PolarHBondContact O-N 2.84Å; A11-L14 PolarHBondContact O-N 3.31Å; L14-M16 PolarHBondContact O-N 2.98Å; L14-F17 PolarHBondContact O-N 3.32Å; L14-M18 VanDerWaalsContact O-CG 3.29Å; L14-M18 WeakPolarHBondContact O-CG 3.43Å; L14-M18 PolarHBondContact O-N 3.36Å; L14-I169 HydrophobicContact CB-CG2 4.13Å; L14-I169 HydrophobicContact CD2-CG2 4.06Å; L14-I169 HydrophobicContact CG-CG2 4.45Å; L14-I172 HydrophobicContact CD1-CB 4.23Å; L14-I172 HydrophobicContact CD1-CG2 3.65Å; L14-A173 HydrophobicContact CB-CB 4.21Å; L14-A173 HydrophobicContact CD1-CB 4.41Å; L14-L176 HydrophobicContact CD1-CD1 3.89Å
15I95.1Very high91.4Very high1 Ų120 Ų201%0.00511%0.11CC..Hα-helixtrans-56.4-50.8176.1-73.9171.1000110.8A11 I13 S19 L78 L111 V177 F181A11-I15 WeakPolarHBondContact O-CB 3.4Å; A11-I15 WeakPolarHBondContact O-CG1 3.36Å; A11-I15 PolarHBondContact O-N 3.35Å; I13-I15 PolarHBondContact O-N 2.92Å; I15-S19 PolarHBondContact O-N 3.19Å; I15-L78 HydrophobicContact CG1-CD2 4.25Å; I15-L111 HydrophobicContact CD1-CD2 4.49Å; I15-L111 HydrophobicContact CG1-CD2 4.29Å; I15-L111 HydrophobicContact CG2-CB 3.64Å; I15-L111 HydrophobicContact CG2-CD1 4.36Å; I15-L111 HydrophobicContact CG2-CD2 3.98Å; I15-L111 HydrophobicContact CG2-CG 4.15Å; I15-V177 HydrophobicContact CD1-CG2 4.19Å; I15-F181 HydrophobicContact CD1-CZ 4.19Å
16M92.6Very high91.2Very high3 Ų318.8 Ų18.82%0.01510%0.102CC..Hα-helixtrans-69.2-36.1179.8-173.360.874.500112.1L12 I13 L14 S19 A20 S115 V135 V138 W139L12-M16 WeakPolarHBondContact O-CB 3.38Å; L12-M16 PolarHBondContact O-N 3.43Å; I13-M16 PolarHBondContact O-N 3.01Å; L14-M16 PolarHBondContact O-N 2.98Å; M16-S19 PolarHBondContact O-N 3.14Å; M16-A20 WeakPolarHBondContact O-CB 3.45Å; M16-A20 PolarHBondContact O-N 2.94Å; M16-S115 VanDerWaalsContact CE-CB 3.44Å; M16-S115 WeakPolarHBondContact CE-OG 3.13Å; M16-V135 HydrophobicContact CB-CG1 3.89Å; M16-V135 HydrophobicContact CE-CG1 3.69Å; M16-V135 HydrophobicContact CG-CG1 4.02Å; M16-V135 WeakPolarHBondContact CG-O 3.07Å; M16-V138 HydrophobicContact CB-CB 4.43Å; M16-V138 HydrophobicContact CB-CG1 4.42Å; M16-V138 HydrophobicContact CG-CB 4.01Å; M16-V138 HydrophobicContact CG-CG1 4.24Å; M16-W139 PolarHBondContact SD-NE1 3.28Å
17F93Very high90.7Very high29 Ų2917.8 Ų17.813%0.12710%0.101CC..Hα-helixtrans-62.8-46.4-179.4177.2-101.6000111.5I13 L14 S19 A20 I21 V138 S142 I145 I169I13-F17 WeakPolarHBondContact O-CB 3.4Å; I13-F17 PolarHBondContact O-N 3.28Å; L14-F17 PolarHBondContact O-N 3.32Å; F17-S19 PolarHBondContact O-N 3.24Å; F17-A20 PolarHBondContact O-N 3.42Å; F17-I21 HydrophobicContact CE1-CD1 3.91Å; F17-I21 HydrophobicContact CE1-CG2 4.4Å; F17-I21 HydrophobicContact CE2-CB 4.45Å; F17-I21 HydrophobicContact CE2-CD1 3.69Å; F17-I21 HydrophobicContact CE2-CG1 4.5Å; F17-I21 HydrophobicContact CZ-CB 4.45Å; F17-I21 HydrophobicContact CZ-CD1 3.26Å; F17-I21 HydrophobicContact CZ-CG1 4.37Å; F17-I21 VanDerWaalsContact O-CB 3.28Å; F17-I21 WeakPolarHBondContact O-CB 3.22Å; F17-I21 VanDerWaalsContact O-CG2 3.23Å; F17-I21 WeakPolarHBondContact O-CG2 3.48Å; F17-I21 PolarHBondContact O-N 3.4Å; F17-V138 VanDerWaalsContact CA-CG1 3.43Å; F17-V138 HydrophobicContact CB-CG1 3.72Å; F17-V138 HydrophobicContact CD2-CG1 4.06Å; F17-V138 HydrophobicContact CG-CG1 4.41Å; F17-S142 WeakPolarHBondContact CD2-OG 3.49Å; F17-I145 HydrophobicContact CE2-CB 4.3Å; F17-I145 HydrophobicContact CE2-CD1 4.08Å; F17-I145 HydrophobicContact CE2-CG2 4.08Å; F17-I145 HydrophobicContact CZ-CG2 3.88Å; F17-I169 HydrophobicContact CD1-CD1 4.22Å; F17-I169 HydrophobicContact CE1-CD1 3.88Å
18M92.6Very high90.1Very high0 Ų018.8 Ų18.80%011%0.107CC..Hα-helixtrans-57.6-46.8176.8-70.4166.757.600111.7L14 F81 I169 A170L14-M18 VanDerWaalsContact O-CG 3.29Å; L14-M18 WeakPolarHBondContact O-CG 3.43Å; L14-M18 PolarHBondContact O-N 3.36Å; M18-F81 HydrophobicContact CB-CE1 4Å; M18-F81 HydrophobicContact CB-CZ 3.98Å; M18-F81 HydrophobicContact CE-CD1 3.11Å; M18-F81 HydrophobicContact CE-CE1 3.28Å; M18-F81 HydrophobicContact CE-CG 3.96Å; M18-F81 HydrophobicContact CE-CZ 4.23Å; M18-I169 HydrophobicContact CG-CB 4.19Å; M18-I169 HydrophobicContact CG-CG2 3.61Å; M18-I169 HydrophobicContact SD-CB 4.15Å; M18-I169 HydrophobicContact SD-CG2 3.64Å; M18-A170 HydrophobicContact CE-CB 3.49Å; M18-A170 VanDerWaalsContact CE-CB 3.49Å; M18-A170 HydrophobicContact SD-CB 4.14Å
19S88.5Confident89.8Confident6 Ų618.6 Ų18.64%0.04211%0.106CC..Hα-helixtrans-67.9-38.3177.9-64.90000113.1I15 M16 F17 S108I15-S19 PolarHBondContact O-N 3.19Å; M16-S19 PolarHBondContact O-N 3.14Å; F17-S19 PolarHBondContact O-N 3.24Å; S19-S108 WeakPolarHBondContact CB-OG 3.28Å; S19-S108 PolarHBondContact OG-OG 3.26Å
20A85.9Confident89.5Confident2 Ų220.2 Ų20.22%0.01711%0.114CC..Hα-helixtrans-78.1-37.8-175.600000113M16 F17 E22 S23 W139M16-A20 WeakPolarHBondContact O-CB 3.45Å; M16-A20 PolarHBondContact O-N 2.94Å; F17-A20 PolarHBondContact O-N 3.42Å; A20-E22 VanDerWaalsContact C-N 3.28Å; A20-E22 PolarHBondContact O-N 3.37Å; A20-S23 PolarHBondContact O-OG 3.37Å; A20-W139 HydrophobicContact CB-CD2 3.87Å; A20-W139 HydrophobicContact CB-CE3 4.15Å; A20-W139 HydrophobicContact CB-CG 4.18Å; A20-W139 HydrophobicContact CB-CZ2 4.36Å
21I88.4Confident89.1Confident2 Ų220.9 Ų20.91%0.0112%0.123CC..Hα-helixtrans-72.2-25.8-175.8-157.9168.6000112.4F17 S23 S24 I25 I145F17-I21 HydrophobicContact CE1-CD1 3.91Å; F17-I21 HydrophobicContact CE1-CG2 4.4Å; F17-I21 HydrophobicContact CE2-CB 4.45Å; F17-I21 HydrophobicContact CE2-CD1 3.69Å; F17-I21 HydrophobicContact CE2-CG1 4.5Å; F17-I21 HydrophobicContact CZ-CB 4.45Å; F17-I21 HydrophobicContact CZ-CD1 3.26Å; F17-I21 HydrophobicContact CZ-CG1 4.37Å; F17-I21 VanDerWaalsContact O-CB 3.28Å; F17-I21 WeakPolarHBondContact O-CB 3.22Å; F17-I21 VanDerWaalsContact O-CG2 3.23Å; F17-I21 WeakPolarHBondContact O-CG2 3.48Å; F17-I21 PolarHBondContact O-N 3.4Å; I21-S23 PolarHBondContact O-N 3.25Å; I21-S24 PolarHBondContact O-N 3.05Å; I21-S24 VanDerWaalsContact O-N 3.11Å; I21-S24 PolarHBondContact O-OG 3.28Å; I21-I25 HydrophobicContact CB-CD1 4.47Å; I21-I25 HydrophobicContact CD1-CD1 3.51Å; I21-I25 HydrophobicContact CD1-CG1 4.21Å; I21-I25 HydrophobicContact CG1-CD1 3.46Å; I21-I25 VanDerWaalsContact CG1-CD1 3.46Å; I21-I25 HydrophobicContact CG1-CG1 3.76Å; I21-I25 HydrophobicContact CG2-CD1 4.33Å; I21-I25 PolarHBondContact O-N 3.02Å; I21-I145 HydrophobicContact CD1-CB 4.43Å; I21-I145 HydrophobicContact CD1-CG2 3.93Å
22E86.1Confident88.8Confident4 Ų424.1 Ų24.12%0.01914%0.143CC..Hα-helixtrans-59.6-42.9-172.7-171.3162.9-178.500114.1A20 I26 Y50 F81 R101 Q104A20-E22 VanDerWaalsContact C-N 3.28Å; A20-E22 PolarHBondContact O-N 3.37Å; E22-I26 HydrophobicContact CG-CD1 3.76Å; E22-I26 WeakPolarHBondContact O-CB 3.31Å; E22-I26 VanDerWaalsContact O-CG1 3.32Å; E22-I26 WeakPolarHBondContact O-CG1 3.49Å; E22-I26 PolarHBondContact O-N 3.31Å; E22-I26 VanDerWaalsContact O-N 3.15Å; E22-Y50 WeakPolarHBondContact OE2-CE2 3.3Å; E22-Y50 PolarHBondContact OE2-OH 3.43Å; E22-Y50 VanDerWaalsContact OE2-OH 3.13Å; E22-F81 VanDerWaalsContact OE2-CE2 3.25Å; E22-F81 WeakPolarHBondContact OE2-CE2 3.47Å; E22-F81 VanDerWaalsContact OE2-CZ 3.27Å; E22-F81 WeakPolarHBondContact OE2-CZ 3.28Å; E22-R101 IonicContact OE1-CZ 3.64Å; E22-R101 IonicContact OE1-NH1 2.62Å; E22-R101 PolarHBondContact OE1-NH1 3.05Å; E22-Q104 PolarHBondContact OE1-NE2 3.25Å; E22-Q104 PolarHBondContact OE1-OE1 2.9Å
23S77.6Confident88.6Confident34 Ų3424.1 Ų24.124%0.23814%0.143CC..Hα-helixtrans-67.8-38.5176.959.30000111.9A20 I21 S27A20-S23 PolarHBondContact O-OG 3.37Å; I21-S23 PolarHBondContact O-N 3.25Å; S23-S27 WeakPolarHBondContact O-CB 3.4Å; S23-S27 PolarHBondContact O-N 3.25Å; S23-S27 PolarHBondContact O-OG 3.17Å
24S79.9Confident88.4Confident19 Ų1925.7 Ų25.713%0.13315%0.148CC..Hα-helixtrans-73.8-35.9-17867.80000113.9I21 S27 S142I21-S24 PolarHBondContact O-N 3.05Å; I21-S24 VanDerWaalsContact O-N 3.11Å; I21-S24 PolarHBondContact O-OG 3.28Å; S24-S27 PolarHBondContact O-OG 3.45Å; S24-S142 PolarHBondContact OG-O 3.05Å
25I87Confident88.2Confident2 Ų231.4 Ų31.41%0.0117%0.173CC..Hα-helixtrans-76.1-45.9178.4-79.4179.2000110.3I21 S27 L28 G146 L149 L162 I165I21-I25 HydrophobicContact CB-CD1 4.47Å; I21-I25 HydrophobicContact CD1-CD1 3.51Å; I21-I25 HydrophobicContact CD1-CG1 4.21Å; I21-I25 HydrophobicContact CG1-CD1 3.46Å; I21-I25 VanDerWaalsContact CG1-CD1 3.46Å; I21-I25 HydrophobicContact CG1-CG1 3.76Å; I21-I25 HydrophobicContact CG2-CD1 4.33Å; I21-I25 PolarHBondContact O-N 3.02Å; I25-S27 VanDerWaalsContact C-N 3.32Å; I25-S27 PolarHBondContact O-N 2.96Å; I25-L28 WeakPolarHBondContact O-CB 3.48Å; I25-L28 PolarHBondContact O-N 3.43Å; I25-G146 WeakPolarHBondContact CG1-O 3.4Å; I25-L149 HydrophobicContact CD1-CD2 3.69Å; I25-L162 HydrophobicContact CG2-CB 3.64Å; I25-L162 HydrophobicContact CG2-CD1 3.8Å; I25-L162 HydrophobicContact CG2-CD2 3.63Å; I25-L162 HydrophobicContact CG2-CG 3.88Å; I25-I165 HydrophobicContact CD1-CD1 3.51Å
26I86.8Confident88.2Confident2 Ų235.5 Ų35.51%0.0120%0.195CC..Hα-helixtrans-77.9-24.6-169.1-61.2174.6000111.4E22 L28 A29 L30 I33 I46 F47 F163E22-I26 HydrophobicContact CG-CD1 3.76Å; E22-I26 WeakPolarHBondContact O-CB 3.31Å; E22-I26 VanDerWaalsContact O-CG1 3.32Å; E22-I26 WeakPolarHBondContact O-CG1 3.49Å; E22-I26 PolarHBondContact O-N 3.31Å; E22-I26 VanDerWaalsContact O-N 3.15Å; I26-L28 PolarHBondContact O-N 2.97Å; I26-A29 PolarHBondContact O-N 3.26Å; I26-A29 VanDerWaalsContact O-N 3.09Å; I26-L30 WeakPolarHBondContact O-CG 3.2Å; I26-L30 PolarHBondContact O-N 2.87Å; I26-I33 HydrophobicContact CG2-CD1 3.97Å; I26-I46 HydrophobicContact CG2-CG2 4.4Å; I26-F47 HydrophobicContact CB-CE1 4.44Å; I26-F47 HydrophobicContact CG2-CZ 4.39Å; I26-F163 HydrophobicContact CD1-CD1 3.99Å; I26-F163 HydrophobicContact CD1-CE1 3.24Å; I26-F163 HydrophobicContact CD1-CE2 4.31Å; I26-F163 HydrophobicContact CD1-CZ 3.44Å; I26-F163 VanDerWaalsContact CD1-CZ 3.44Å; I26-F163 HydrophobicContact CG1-CE1 4.42Å; I26-F163 HydrophobicContact CG1-CZ 4.27Å
27S82.2Confident88.4Confident55 Ų5536 Ų3639%0.38520%0.198SC..Hα-helixtrans-56.8-35.4171.462.30000112.7S23 S24 I25 A29 L30S23-S27 WeakPolarHBondContact O-CB 3.4Å; S23-S27 PolarHBondContact O-N 3.25Å; S23-S27 PolarHBondContact O-OG 3.17Å; S24-S27 PolarHBondContact O-OG 3.45Å; I25-S27 VanDerWaalsContact C-N 3.32Å; I25-S27 PolarHBondContact O-N 2.96Å; S27-A29 VanDerWaalsContact C-N 3.34Å; S27-A29 PolarHBondContact O-N 2.97Å; S27-L30 WeakPolarHBondContact O-CG 3.29Å
28L84.2Confident88.4Confident54 Ų5441.5 Ų41.528%0.28323%0.229SC..Hα-helixtrans-67.9-31.9176.4-69.2177.6000113.3I25 I26 P147 L154 P290I25-L28 WeakPolarHBondContact O-CB 3.48Å; I25-L28 PolarHBondContact O-N 3.43Å; I26-L28 PolarHBondContact O-N 2.97Å; L28-P147 HydrophobicContact CD1-CB 4.13Å; L28-L154 HydrophobicContact CB-CD1 4.23Å; L28-P290 HydrophobicContact CD2-CB 4.48Å; L28-P290 HydrophobicContact CD2-CG 4.28Å
29A89.4Confident88.2Confident0 Ų041.9 Ų41.90%023%0.231CC..Hα-helixtrans-90.1-4.5-176.400000113.7I26 S27 P31 T32 I33 L154 W159 L162I26-A29 PolarHBondContact O-N 3.26Å; I26-A29 VanDerWaalsContact O-N 3.09Å; S27-A29 VanDerWaalsContact C-N 3.34Å; S27-A29 PolarHBondContact O-N 2.97Å; A29-P31 VanDerWaalsContact C-CD 3.45Å; A29-T32 PolarHBondContact O-N 3.36Å; A29-T32 VanDerWaalsContact O-N 3.14Å; A29-I33 HydrophobicContact CB-CD1 3.72Å; A29-I33 HydrophobicContact CB-CG1 4.13Å; A29-I33 VanDerWaalsContact O-CG1 3.3Å; A29-I33 WeakPolarHBondContact O-CG1 3.49Å; A29-I33 PolarHBondContact O-N 3.28Å; A29-L154 HydrophobicContact CB-CD1 4.1Å; A29-L154 HydrophobicContact CB-CD2 4.23Å; A29-W159 HydrophobicContact CB-CB 4.06Å; A29-L162 HydrophobicContact CB-CD1 3.48Å; A29-L162 VanDerWaalsContact CB-CD1 3.48Å
30L88.3Confident88.2Confident46 Ų4643.1 Ų43.124%0.24125%0.246CC..Hα-helixtrans-52.9-43.6-176-66.9171.9000114.2I26 S27 K34 I43 F47I26-L30 WeakPolarHBondContact O-CG 3.2Å; I26-L30 PolarHBondContact O-N 2.87Å; S27-L30 WeakPolarHBondContact O-CG 3.29Å; L30-K34 VanDerWaalsContact O-CB 3.23Å; L30-K34 WeakPolarHBondContact O-CB 3.15Å; L30-K34 PolarHBondContact O-N 3.31Å; L30-I43 HydrophobicContact CD2-CD1 4.46Å; L30-I43 HydrophobicContact CD2-CG1 4.11Å; L30-F47 HydrophobicContact CD1-CE2 3.74Å; L30-F47 HydrophobicContact CD1-CZ 4.22Å; L30-F47 HydrophobicContact CD2-CE2 3.6Å; L30-F47 HydrophobicContact CD2-CZ 3.99Å; L30-F47 HydrophobicContact CG-CE2 4.15Å; L30-F47 HydrophobicContact CG-CZ 4.38Å
31P87.7Confident88.1Confident89 Ų8950.1 Ų50.158%0.57828%0.283SS*.Hα-helixtrans-62.3-45.5179.3-22.135000111.5A29 K34 Q35A29-P31 VanDerWaalsContact C-CD 3.45Å; P31-K34 PolarHBondContact O-N 2.75Å; P31-Q35 PolarHBondContact O-N 3.06Å; P31-Q35 VanDerWaalsContact O-N 3.12Å
32T91.2Very high88Confident68 Ų6855.2 Ų55.242%0.41731%0.31SS..Hα-helixtrans-66.2-45.1179.7-46.30000111.4A29 K34 Q35 D36A29-T32 PolarHBondContact O-N 3.36Å; A29-T32 VanDerWaalsContact O-N 3.14Å; T32-K34 VanDerWaalsContact C-N 3.33Å; T32-K34 PolarHBondContact O-N 3.36Å; T32-Q35 PolarHBondContact O-N 3.44Å; T32-D36 VanDerWaalsContact O-CB 3.28Å; T32-D36 WeakPolarHBondContact O-CB 3.45Å; T32-D36 PolarHBondContact O-N 3.46Å
33I92.8Very high88.1Confident0 Ų056.3 Ų56.30%032%0.315CS..Hα-helixtrans-62.2-41.5177.2-65.4166.3000110.8I26 A29 Q35 L37 I43 I46 L97 W159I26-I33 HydrophobicContact CG2-CD1 3.97Å; A29-I33 HydrophobicContact CB-CD1 3.72Å; A29-I33 HydrophobicContact CB-CG1 4.13Å; A29-I33 VanDerWaalsContact O-CG1 3.3Å; A29-I33 WeakPolarHBondContact O-CG1 3.49Å; A29-I33 PolarHBondContact O-N 3.28Å; I33-Q35 VanDerWaalsContact C-N 3.29Å; I33-Q35 PolarHBondContact O-N 3.36Å; I33-L37 HydrophobicContact CG2-CD1 4.05Å; I33-L37 HydrophobicContact CG2-CG 4.49Å; I33-L37 WeakPolarHBondContact O-CB 3.47Å; I33-L37 PolarHBondContact O-N 3.2Å; I33-I43 HydrophobicContact CB-CD1 4.3Å; I33-I43 HydrophobicContact CG2-CD1 3.92Å; I33-I46 HydrophobicContact CG2-CD1 3.6Å; I33-L97 HydrophobicContact CG2-CD2 3.78Å; I33-W159 HydrophobicContact CD1-CD2 4.32Å; I33-W159 HydrophobicContact CD1-CE3 4.09Å; I33-W159 HydrophobicContact CG1-CB 4.19Å; I33-W159 HydrophobicContact CG1-CD2 3.59Å; I33-W159 HydrophobicContact CG1-CE3 3.82Å; I33-W159 HydrophobicContact CG1-CG 3.76Å; I33-W159 HydrophobicContact CG1-CZ3 4.49Å
34K91.5Very high88.4Confident87 Ų8757.5 Ų57.538%0.37832%0.324SS..Hα-helixtrans-59.6-42.3177.8178.8177.1172.31700111.7L30 P31 T32 N38 A39 G40 I43L30-K34 VanDerWaalsContact O-CB 3.23Å; L30-K34 WeakPolarHBondContact O-CB 3.15Å; L30-K34 PolarHBondContact O-N 3.31Å; P31-K34 PolarHBondContact O-N 2.75Å; T32-K34 VanDerWaalsContact C-N 3.33Å; T32-K34 PolarHBondContact O-N 3.36Å; K34-N38 WeakPolarHBondContact O-CA 3.26Å; K34-N38 PolarHBondContact O-N 2.71Å; K34-A39 PolarHBondContact O-N 2.89Å; K34-G40 WeakPolarHBondContact CE-O 3.34Å; K34-I43 HydrophobicContact CB-CB 4.4Å; K34-I43 HydrophobicContact CB-CD1 3.9Å; K34-I43 HydrophobicContact CB-CG1 4.02Å; K34-I43 HydrophobicContact CD-CG2 4.34Å; K34-I43 HydrophobicContact CG-CB 4.45Å
35Q92.7Very high88.8Confident156 Ų15659.7 Ų59.773%0.72933%0.333SS*.Hα-helixtrans-73.3-50179.7-174.8176.12.300111.7P31 T32 I33 L37 N38P31-Q35 PolarHBondContact O-N 3.06Å; P31-Q35 VanDerWaalsContact O-N 3.12Å; T32-Q35 PolarHBondContact O-N 3.44Å; I33-Q35 VanDerWaalsContact C-N 3.29Å; I33-Q35 PolarHBondContact O-N 3.36Å; Q35-L37 PolarHBondContact O-N 2.92Å; Q35-N38 PolarHBondContact O-N 3.23Å
36D95.1Very high89Confident87 Ų8759.6 Ų59.647%0.46533%0.333SS..Hα-helixtrans-64.5-39.4-174.4-165.138.6000112.3T32 W159 H160T32-D36 VanDerWaalsContact O-CB 3.28Å; T32-D36 WeakPolarHBondContact O-CB 3.45Å; T32-D36 PolarHBondContact O-N 3.46Å; D36-W159 PolarHBondContact OD2-NE1 3.43Å; D36-H160 IonicContact OD2-CE1 3.74Å
37L95.4Very high89Confident14 Ų1461.6 Ų61.67%0.07334%0.342CS..THydrogen-bonded Turntrans-99.37.6-178.5-57.7-173.5000114.2I33 Q35 A39 F94 L97 W159I33-L37 HydrophobicContact CG2-CD1 4.05Å; I33-L37 HydrophobicContact CG2-CG 4.49Å; I33-L37 WeakPolarHBondContact O-CB 3.47Å; I33-L37 PolarHBondContact O-N 3.2Å; Q35-L37 PolarHBondContact O-N 2.92Å; L37-A39 PolarHBondContact O-N 3.39Å; L37-F94 HydrophobicContact CB-CB 4.25Å; L37-L97 HydrophobicContact CD1-CB 4.08Å; L37-L97 HydrophobicContact CD1-CD2 3.6Å; L37-L97 HydrophobicContact CD1-CG 4.46Å; L37-W159 HydrophobicContact CD1-CH2 3.84Å; L37-W159 HydrophobicContact CD1-CZ2 3.83Å; L37-W159 HydrophobicContact CD2-CZ2 3.99Å; L37-W159 HydrophobicContact CG-CH2 4.43Å; L37-W159 HydrophobicContact CG-CZ2 3.91Å
38N92.7Very high89.2Confident145 Ų14560.6 Ų60.678%0.77533%0.333SS*.THydrogen-bonded Turntrans49.939.9-177-64.1-64.8000113.7K34 Q35 G40K34-N38 WeakPolarHBondContact O-CA 3.26Å; K34-N38 PolarHBondContact O-N 2.71Å; Q35-N38 PolarHBondContact O-N 3.23Å; N38-G40 VanDerWaalsContact C-N 3.28Å; N38-G40 PolarHBondContact O-N 3.29Å
39A88.1Confident89.6Confident7 Ų758.4 Ų58.46%0.05832%0.323CS..  trans-70.8-20.9-171.300000114.2K34 L37 N41 L42 I43 F94K34-A39 PolarHBondContact O-N 2.89Å; L37-A39 PolarHBondContact O-N 3.39Å; A39-N41 PolarHBondContact O-N 2.94Å; A39-L42 WeakPolarHBondContact O-CB 3.44Å; A39-L42 PolarHBondContact O-N 3.48Å; A39-L42 VanDerWaalsContact O-N 3.08Å; A39-I43 HydrophobicContact CB-CB 4.26Å; A39-I43 HydrophobicContact CB-CD1 3.97Å; A39-F94 HydrophobicContact CB-CD1 4.38Å; A39-F94 HydrophobicContact CB-CD2 3.37Å; A39-F94 HydrophobicContact CB-CE1 4.48Å; A39-F94 HydrophobicContact CB-CE2 3.48Å; A39-F94 VanDerWaalsContact CB-CE2 3.48Å; A39-F94 HydrophobicContact CB-CG 3.85Å; A39-F94 HydrophobicContact CB-CZ 4.07Å
40G89.1Confident89.7Confident33 Ų3358.9 Ų58.934%0.3433%0.325SS..G310 helixtrans56.2-131-178.800000112.7K34 N38 L42K34-G40 WeakPolarHBondContact CE-O 3.34Å; N38-G40 VanDerWaalsContact C-N 3.28Å; N38-G40 PolarHBondContact O-N 3.29Å; G40-L42 VanDerWaalsContact C-N 3.28Å
41N83.3Confident89.7Confident148 Ų14859.4 Ų59.479%0.79133%0.325SS*.G310 helixtrans-79.5-9.9179.7-67.8-13.2000113.3A39 I43A39-N41 PolarHBondContact O-N 2.94Å; N41-I43 PolarHBondContact O-N 3.06Å
42L87Confident89.8Confident110 Ų11057.8 Ų57.858%0.57631%0.311SS*.G310 helixtrans-80.1-3.7179.8-61.4175.7000113A39 G40 S44 L45 F94A39-L42 WeakPolarHBondContact O-CB 3.44Å; A39-L42 PolarHBondContact O-N 3.48Å; A39-L42 VanDerWaalsContact O-N 3.08Å; G40-L42 VanDerWaalsContact C-N 3.28Å; L42-S44 PolarHBondContact O-N 3Å; L42-L45 WeakPolarHBondContact O-CB 3.47Å; L42-L45 PolarHBondContact O-N 3.26Å; L42-F94 HydrophobicContact CB-CD1 4.45Å; L42-F94 HydrophobicContact CB-CE1 3.68Å; L42-F94 HydrophobicContact CB-CZ 4.21Å; L42-F94 WeakPolarHBondContact O-CZ 3.26Å
43I88.6Confident90Very high27 Ų2754.6 Ų54.614%0.13829%0.291CS..G310 helixtrans-51.8-32.8-175.4-17164.6000113.9L30 I33 K34 A39 N41 L45 I46 F94L30-I43 HydrophobicContact CD2-CD1 4.46Å; L30-I43 HydrophobicContact CD2-CG1 4.11Å; I33-I43 HydrophobicContact CB-CD1 4.3Å; I33-I43 HydrophobicContact CG2-CD1 3.92Å; K34-I43 HydrophobicContact CB-CB 4.4Å; K34-I43 HydrophobicContact CB-CD1 3.9Å; K34-I43 HydrophobicContact CB-CG1 4.02Å; K34-I43 HydrophobicContact CD-CG2 4.34Å; K34-I43 HydrophobicContact CG-CB 4.45Å; A39-I43 HydrophobicContact CB-CB 4.26Å; A39-I43 HydrophobicContact CB-CD1 3.97Å; N41-I43 PolarHBondContact O-N 3.06Å; I43-L45 PolarHBondContact O-N 3.04Å; I43-I46 HydrophobicContact CD1-CD1 3.46Å; I43-I46 VanDerWaalsContact CD1-CD1 3.46Å; I43-I46 HydrophobicContact CD1-CG1 4.4Å; I43-I46 HydrophobicContact CG1-CD1 4.43Å; I43-I46 WeakPolarHBondContact O-CB 3.43Å; I43-I46 WeakPolarHBondContact O-CG1 3.45Å; I43-I46 PolarHBondContact O-N 3.23Å; I43-F94 HydrophobicContact CD1-CE2 4.26Å
44S83.3Confident90Very high59 Ų5954.7 Ų54.741%0.41329%0.292SS..G310 helixtrans-61.8-25.1176.956.80000113.2L42 I46 F47 T48L42-S44 PolarHBondContact O-N 3Å; S44-I46 PolarHBondContact O-N 3.39Å; S44-I46 VanDerWaalsContact O-N 3.12Å; S44-F47 PolarHBondContact O-N 2.95Å; S44-F47 VanDerWaalsContact O-N 3.14Å; S44-T48 PolarHBondContact O-N 3.28Å; S44-T48 PolarHBondContact O-OG1 3.15Å
45L88.8Confident90Very high65 Ų6550.6 Ų50.634%0.3427%0.274SS..Hα-helixtrans-60.7-22.5178.9-168.162.8000112.5L42 I43 F47 T48 A49 F94 I98L42-L45 WeakPolarHBondContact O-CB 3.47Å; L42-L45 PolarHBondContact O-N 3.26Å; I43-L45 PolarHBondContact O-N 3.04Å; L45-F47 VanDerWaalsContact C-N 3.31Å; L45-F47 PolarHBondContact O-N 3.26Å; L45-T48 HydrophobicContact CD1-CG2 4.3Å; L45-T48 PolarHBondContact O-N 3.1Å; L45-A49 WeakPolarHBondContact O-CB 3.41Å; L45-A49 PolarHBondContact O-N 3.04Å; L45-F94 HydrophobicContact CB-CE1 4.4Å; L45-F94 HydrophobicContact CB-CZ 4.25Å; L45-F94 HydrophobicContact CD2-CE1 4.45Å; L45-I98 HydrophobicContact CB-CD1 3.93Å; L45-I98 HydrophobicContact CD2-CD1 4.21Å; L45-I98 HydrophobicContact CD2-CG1 4.07Å; L45-I98 HydrophobicContact CD2-CG2 4.15Å; L45-I98 HydrophobicContact CG-CD1 3.86Å; L45-I98 HydrophobicContact CG-CG1 4.26Å; L45-I98 HydrophobicContact CG-CG2 4.3Å
46I90.4Very high90Very high0 Ų045.8 Ų45.80%025%0.253CS..Hα-helixtrans-55.1-46.3174.4-70.9-178.5000111.3I26 I33 I43 S44 F94 L97 I98 R101I26-I46 HydrophobicContact CG2-CG2 4.4Å; I33-I46 HydrophobicContact CG2-CD1 3.6Å; I43-I46 HydrophobicContact CD1-CD1 3.46Å; I43-I46 VanDerWaalsContact CD1-CD1 3.46Å; I43-I46 HydrophobicContact CD1-CG1 4.4Å; I43-I46 HydrophobicContact CG1-CD1 4.43Å; I43-I46 WeakPolarHBondContact O-CB 3.43Å; I43-I46 WeakPolarHBondContact O-CG1 3.45Å; I43-I46 PolarHBondContact O-N 3.23Å; S44-I46 PolarHBondContact O-N 3.39Å; S44-I46 VanDerWaalsContact O-N 3.12Å; I46-F94 HydrophobicContact CD1-CE2 3.83Å; I46-F94 HydrophobicContact CG1-CE2 3.58Å; I46-F94 HydrophobicContact CG1-CZ 4.03Å; I46-L97 HydrophobicContact CD1-CD2 3.59Å; I46-L97 HydrophobicContact CG1-CD2 4.04Å; I46-I98 HydrophobicContact CB-CD1 4.47Å; I46-I98 HydrophobicContact CG1-CD1 3.96Å; I46-R101 HydrophobicContact CG2-CG 4.31Å
47F87.6Confident90Very high44 Ų4441.7 Ų41.719%0.19323%0.231CC..Hα-helixtrans-79.2-42.5177.5-63.5-68.2000111I26 L30 S44 L45 A49 Y50 F51I26-F47 HydrophobicContact CB-CE1 4.44Å; I26-F47 HydrophobicContact CG2-CZ 4.39Å; L30-F47 HydrophobicContact CD1-CE2 3.74Å; L30-F47 HydrophobicContact CD1-CZ 4.22Å; L30-F47 HydrophobicContact CD2-CE2 3.6Å; L30-F47 HydrophobicContact CD2-CZ 3.99Å; L30-F47 HydrophobicContact CG-CE2 4.15Å; L30-F47 HydrophobicContact CG-CZ 4.38Å; S44-F47 PolarHBondContact O-N 2.95Å; S44-F47 VanDerWaalsContact O-N 3.14Å; L45-F47 VanDerWaalsContact C-N 3.31Å; L45-F47 PolarHBondContact O-N 3.26Å; F47-A49 PolarHBondContact O-N 3.49Å; F47-Y50 PolarHBondContact O-N 3.38Å; F47-F51 HydrophobicContact CB-CD2 4.08Å; F47-F51 HydrophobicContact CB-CE2 4.01Å; F47-F51 WeakPolarHBondContact O-CD2 3.32Å; F47-F51 PolarHBondContact O-N 3.36Å
48T85.8Confident89.8Confident34 Ų3441 Ų4121%0.20923%0.228CC..Hα-helixtrans-58.6-46.5-177.4-57.10000112.1S44 L45 Y50 F51 I52 L214S44-T48 PolarHBondContact O-N 3.28Å; S44-T48 PolarHBondContact O-OG1 3.15Å; L45-T48 HydrophobicContact CD1-CG2 4.3Å; L45-T48 PolarHBondContact O-N 3.1Å; T48-Y50 PolarHBondContact O-N 2.91Å; T48-F51 PolarHBondContact O-N 3.33Å; T48-I52 HydrophobicContact CG2-CD1 3.79Å; T48-I52 HydrophobicContact CG2-CG1 4.33Å; T48-I52 WeakPolarHBondContact O-CB 3.45Å; T48-I52 VanDerWaalsContact O-CG1 3.26Å; T48-I52 WeakPolarHBondContact O-CG1 3.44Å; T48-I52 PolarHBondContact O-N 3.39Å; T48-L214 HydrophobicContact CG2-CD1 3.63Å; T48-L214 HydrophobicContact CG2-CD2 3.9Å; T48-L214 HydrophobicContact CG2-CG 4.24Å
49A92.1Very high89.8Confident7 Ų734.2 Ų34.26%0.05819%0.192CC..Hα-helixtrans-63.6-42.1-179.800000112.3L45 F47 A53 I98 V102L45-A49 WeakPolarHBondContact O-CB 3.41Å; L45-A49 PolarHBondContact O-N 3.04Å; F47-A49 PolarHBondContact O-N 3.49Å; A49-A53 WeakPolarHBondContact O-CB 3.24Å; A49-A53 PolarHBondContact O-N 3.45Å; A49-A53 VanDerWaalsContact O-N 3.14Å; A49-I98 HydrophobicContact CB-CG2 3.82Å; A49-V102 HydrophobicContact CB-CG2 3.89Å
50Y92.4Very high90Very high11 Ų1136.4 Ų36.44%0.04320%0.201CC..Hα-helixtrans-61.6-48.6174.1172.5-91.9000111.7E22 F47 T48 A53 L54 F81 Q104 G105 S108E22-Y50 WeakPolarHBondContact OE2-CE2 3.3Å; E22-Y50 PolarHBondContact OE2-OH 3.43Å; E22-Y50 VanDerWaalsContact OE2-OH 3.13Å; F47-Y50 PolarHBondContact O-N 3.38Å; T48-Y50 PolarHBondContact O-N 2.91Å; Y50-A53 PolarHBondContact O-N 3.18Å; Y50-L54 HydrophobicContact CE1-CD1 4.39Å; Y50-L54 WeakPolarHBondContact O-CB 3.32Å; Y50-L54 PolarHBondContact O-N 2.99Å; Y50-F81 HydrophobicContact CE2-CE2 4.5Å; Y50-Q104 HydrophobicContact CD2-CB 4.34Å; Y50-Q104 HydrophobicContact CD2-CG 4.45Å; Y50-Q104 HydrophobicContact CE2-CG 4.2Å; Y50-G105 VanDerWaalsContact CD2-CA 3.44Å; Y50-G105 WeakPolarHBondContact O-CA 3.48Å; Y50-S108 WeakPolarHBondContact OH-CB 3.17Å; Y50-S108 PolarHBondContact OH-OG 3.47Å
51F88.3Confident90.2Very high57 Ų5734.8 Ų34.825%0.2519%0.185CC..Hα-helixtrans-67.1-39.5-178.9-76.2-55.2000112.9F47 T48 L54 V55F47-F51 HydrophobicContact CB-CD2 4.08Å; F47-F51 HydrophobicContact CB-CE2 4.01Å; F47-F51 WeakPolarHBondContact O-CD2 3.32Å; F47-F51 PolarHBondContact O-N 3.36Å; T48-F51 PolarHBondContact O-N 3.33Å; F51-L54 HydrophobicContact CD1-CD2 4.47Å; F51-L54 PolarHBondContact O-N 3.03Å; F51-V55 WeakPolarHBondContact O-CB 3.32Å; F51-V55 VanDerWaalsContact O-CG2 3.26Å; F51-V55 WeakPolarHBondContact O-CG2 3.4Å; F51-V55 PolarHBondContact O-N 3.43Å
52I89.8Confident90.6Very high55 Ų5527.8 Ų27.828%0.28215%0.148SC..Hα-helixtrans-58.3-50.6173.8-71.7168.9000109.9T48 L54 V55 I56 L214T48-I52 HydrophobicContact CG2-CD1 3.79Å; T48-I52 HydrophobicContact CG2-CG1 4.33Å; T48-I52 WeakPolarHBondContact O-CB 3.45Å; T48-I52 VanDerWaalsContact O-CG1 3.26Å; T48-I52 WeakPolarHBondContact O-CG1 3.44Å; T48-I52 PolarHBondContact O-N 3.39Å; I52-L54 VanDerWaalsContact C-N 3.31Å; I52-L54 PolarHBondContact O-N 2.65Å; I52-V55 PolarHBondContact O-N 2.95Å; I52-I56 HydrophobicContact CG2-CD1 3.63Å; I52-I56 HydrophobicContact CG2-CG1 4.36Å; I52-I56 VanDerWaalsContact O-CG1 3.26Å; I52-I56 WeakPolarHBondContact O-CG1 3.25Å; I52-I56 PolarHBondContact O-N 3.34Å; I52-L214 HydrophobicContact CD1-CD1 3.67Å; I52-L214 HydrophobicContact CG1-CD1 3.64Å
53A94.3Very high90.7Very high1 Ų122.9 Ų22.91%0.00812%0.122CC..Hα-helixtrans-61.6-41-178.900000112.1A49 Y50 I56 A57 V102 F106A49-A53 WeakPolarHBondContact O-CB 3.24Å; A49-A53 PolarHBondContact O-N 3.45Å; A49-A53 VanDerWaalsContact O-N 3.14Å; Y50-A53 PolarHBondContact O-N 3.18Å; A53-I56 PolarHBondContact O-N 2.93Å; A53-A57 WeakPolarHBondContact O-CB 3.48Å; A53-A57 PolarHBondContact O-N 3.41Å; A53-V102 HydrophobicContact CB-CB 4.39Å; A53-V102 HydrophobicContact CB-CG1 4.01Å; A53-V102 WeakPolarHBondContact CB-O 3.05Å; A53-F106 HydrophobicContact CB-CD2 3.86Å; A53-F106 HydrophobicContact CB-CE2 4.02Å; A53-F106 HydrophobicContact CB-CG 4.19Å; A53-F106 HydrophobicContact CB-CZ 4.49Å
54L93.5Very high90.8Very high1 Ų124.2 Ų24.21%0.00513%0.129CC..Hα-helixtrans-62-46.2174.7173.9129.8000112.6Y50 F51 I52 I56 A57 N58 G105 S108 M112 N391Y50-L54 HydrophobicContact CE1-CD1 4.39Å; Y50-L54 WeakPolarHBondContact O-CB 3.32Å; Y50-L54 PolarHBondContact O-N 2.99Å; F51-L54 HydrophobicContact CD1-CD2 4.47Å; F51-L54 PolarHBondContact O-N 3.03Å; I52-L54 VanDerWaalsContact C-N 3.31Å; I52-L54 PolarHBondContact O-N 2.65Å; L54-I56 VanDerWaalsContact C-N 3.29Å; L54-I56 PolarHBondContact O-N 2.9Å; L54-A57 PolarHBondContact O-N 3.35Å; L54-N58 PolarHBondContact O-N 3.37Å; L54-N58 VanDerWaalsContact O-N 3.07Å; L54-N58 PolarHBondContact O-ND2 2.85Å; L54-N58 VanDerWaalsContact O-ND2 3.1Å; L54-G105 WeakPolarHBondContact CA-O 3.31Å; L54-G105 WeakPolarHBondContact CB-O 3.32Å; L54-G105 PolarHBondContact N-O 3.04Å; L54-S108 VanDerWaalsContact CD1-OG 3.3Å; L54-S108 WeakPolarHBondContact CD1-OG 3.41Å; L54-M112 HydrophobicContact CD1-CG 4.35Å; L54-M112 HydrophobicContact CD1-SD 3.63Å; L54-M112 HydrophobicContact CD2-SD 4.46Å; L54-N391 HydrophobicContact CD2-CB 3.69Å
55V91.7Very high91.2Very high1 Ų121.6 Ų21.61%0.00611%0.11CC..Hα-helixtrans-61.3-39.4175.81650000110.8F51 I52 P59 I206 M210 L388 N391 L392F51-V55 WeakPolarHBondContact O-CB 3.32Å; F51-V55 VanDerWaalsContact O-CG2 3.26Å; F51-V55 WeakPolarHBondContact O-CG2 3.4Å; F51-V55 PolarHBondContact O-N 3.43Å; I52-V55 PolarHBondContact O-N 2.95Å; V55-P59 VanDerWaalsContact O-CD 3.31Å; V55-P59 WeakPolarHBondContact O-CD 3.38Å; V55-I206 HydrophobicContact CG1-CG2 3.49Å; V55-I206 VanDerWaalsContact CG1-CG2 3.49Å; V55-M210 HydrophobicContact CB-SD 4.21Å; V55-M210 HydrophobicContact CG1-CG 4.15Å; V55-M210 HydrophobicContact CG1-SD 3.91Å; V55-M210 HydrophobicContact CG2-SD 4.1Å; V55-L388 HydrophobicContact CB-CD1 4.36Å; V55-L388 HydrophobicContact CG1-CD1 3.7Å; V55-L388 VanDerWaalsContact O-CD1 3.23Å; V55-L388 WeakPolarHBondContact O-CD1 3.46Å; V55-N391 HydrophobicContact CG2-CB 4.41Å; V55-L392 HydrophobicContact CG1-CD2 3.83Å; V55-L392 HydrophobicContact CG2-CD2 4.24Å
56I92Very high91.1Very high55 Ų5519.5 Ų19.528%0.28210%0.101SC..Hα-helixtrans-68.4-37.3176.5-68.8170.4000111.2I52 A53 L54 P59 F106 Y203I52-I56 HydrophobicContact CG2-CD1 3.63Å; I52-I56 HydrophobicContact CG2-CG1 4.36Å; I52-I56 VanDerWaalsContact O-CG1 3.26Å; I52-I56 WeakPolarHBondContact O-CG1 3.25Å; I52-I56 PolarHBondContact O-N 3.34Å; A53-I56 PolarHBondContact O-N 2.93Å; L54-I56 VanDerWaalsContact C-N 3.29Å; L54-I56 PolarHBondContact O-N 2.9Å; I56-P59 WeakPolarHBondContact O-CD 3.2Å; I56-F106 HydrophobicContact CB-CE1 4.21Å; I56-F106 HydrophobicContact CG2-CE1 3.69Å; I56-F106 HydrophobicContact CG2-CZ 4.15Å; I56-Y203 HydrophobicContact CB-CE1 4.12Å; I56-Y203 HydrophobicContact CG1-CE1 4.44Å; I56-Y203 HydrophobicContact CG2-CD1 4.2Å; I56-Y203 HydrophobicContact CG2-CE1 3.54Å; I56-Y203 VanDerWaalsContact O-CE1 3.27Å; I56-Y203 WeakPolarHBondContact O-CE1 3.34Å; I56-Y203 PolarHBondContact O-OH 2.74Å
57A94.8Very high90.9Very high2 Ų222.5 Ų22.52%0.01711%0.113CC..Hα-helixtrans-73.1-40.3-17700000113.5A53 L54 P59 I60 F106A53-A57 WeakPolarHBondContact O-CB 3.48Å; A53-A57 PolarHBondContact O-N 3.41Å; L54-A57 PolarHBondContact O-N 3.35Å; A57-P59 VanDerWaalsContact C-CD 3.41Å; A57-I60 VanDerWaalsContact O-CG2 3.26Å; A57-I60 WeakPolarHBondContact O-CG2 3.22Å; A57-I60 PolarHBondContact O-N 2.96Å; A57-F106 HydrophobicContact CB-CD1 3.85Å; A57-F106 WeakPolarHBondContact CB-O 3.38Å
58N92.5Very high91Very high0 Ų025.7 Ų25.70%013%0.127CC..Hα-helixtrans-48.4-51.1-172.8-69.8-45.8000114.9L54 I60 V61 G109 S113 S384 L388 N391L54-N58 PolarHBondContact O-N 3.37Å; L54-N58 VanDerWaalsContact O-N 3.07Å; L54-N58 PolarHBondContact O-ND2 2.85Å; L54-N58 VanDerWaalsContact O-ND2 3.1Å; N58-I60 VanDerWaalsContact C-N 3.35Å; N58-I60 PolarHBondContact O-N 2.99Å; N58-V61 WeakPolarHBondContact O-CB 3.47Å; N58-V61 WeakPolarHBondContact O-CG2 3.37Å; N58-V61 PolarHBondContact O-N 3.24Å; N58-G109 WeakPolarHBondContact OD1-CA 3.3Å; N58-G109 PolarHBondContact OD1-O 3.24Å; N58-S113 WeakPolarHBondContact CA-OG 3.36Å; N58-S113 PolarHBondContact O-OG 3Å; N58-S113 PolarHBondContact OD1-OG 2.83Å; N58-S384 WeakPolarHBondContact O-CB 3.33Å; N58-L388 HydrophobicContact CB-CB 4.05Å; N58-L388 HydrophobicContact CB-CD1 4.43Å; N58-N391 PolarHBondContact ND2-ND2 3.35Å; N58-N391 PolarHBondContact OD1-ND2 3.5Å
59P91.7Very high91.3Very high2 Ų229.6 Ų29.61%0.01314%0.141CC..Hα-helixtrans-69-33.9-171-15.731.4000112.4V55 I56 A57 V61 G62 F202 F247 F385 L388V55-P59 VanDerWaalsContact O-CD 3.31Å; V55-P59 WeakPolarHBondContact O-CD 3.38Å; I56-P59 WeakPolarHBondContact O-CD 3.2Å; A57-P59 VanDerWaalsContact C-CD 3.41Å; P59-V61 PolarHBondContact O-N 3.42Å; P59-G62 PolarHBondContact O-N 3.12Å; P59-F202 HydrophobicContact CB-CD1 4.32Å; P59-F202 HydrophobicContact CB-CE1 3.7Å; P59-F202 HydrophobicContact CB-CZ 4.24Å; P59-F202 HydrophobicContact CG-CD1 4.36Å; P59-F202 HydrophobicContact CG-CE1 3.49Å; P59-F202 VanDerWaalsContact CG-CE1 3.49Å; P59-F202 HydrophobicContact CG-CZ 4.17Å; P59-F247 HydrophobicContact CB-CE1 4.08Å; P59-F247 HydrophobicContact CB-CZ 3.8Å; P59-F385 HydrophobicContact CB-CD1 4.18Å; P59-F385 HydrophobicContact CB-CE1 3.79Å; P59-L388 HydrophobicContact CG-CB 4.45Å; P59-L388 HydrophobicContact CG-CD1 4.05Å; P59-L388 HydrophobicContact CG-CD2 3.91Å; P59-L388 HydrophobicContact CG-CG 4.37Å
60I92.1Very high91.4Very high52 Ų5229.4 Ų29.427%0.26714%0.138SC..Hα-helixtrans-70-22-177.3-148.5165.1000112A57 N58 G62 E63 L64 L199A57-I60 VanDerWaalsContact O-CG2 3.26Å; A57-I60 WeakPolarHBondContact O-CG2 3.22Å; A57-I60 PolarHBondContact O-N 2.96Å; N58-I60 VanDerWaalsContact C-N 3.35Å; N58-I60 PolarHBondContact O-N 2.99Å; I60-G62 VanDerWaalsContact C-N 3.27Å; I60-G62 PolarHBondContact O-N 3.44Å; I60-E63 PolarHBondContact O-N 3.4Å; I60-L64 HydrophobicContact CG2-CD1 4.04Å; I60-L64 VanDerWaalsContact O-CG 3.3Å; I60-L64 WeakPolarHBondContact O-CG 3.46Å; I60-L64 PolarHBondContact O-N 2.98Å; I60-L199 HydrophobicContact CD1-CD1 4.48Å
61V93.9Very high91.5Very high0 Ų029.6 Ų29.60%014%0.14CC..Hα-helixtrans-56.9-43.6177.9178.10000110.9N58 P59 E63 L64 L65 V73 V110 L114 I117N58-V61 WeakPolarHBondContact O-CB 3.47Å; N58-V61 WeakPolarHBondContact O-CG2 3.37Å; N58-V61 PolarHBondContact O-N 3.24Å; P59-V61 PolarHBondContact O-N 3.42Å; V61-E63 VanDerWaalsContact C-N 3.32Å; V61-E63 PolarHBondContact O-N 2.75Å; V61-L64 PolarHBondContact O-N 3.14Å; V61-L65 HydrophobicContact CG1-CD1 3.67Å; V61-L65 HydrophobicContact CG1-CG 4.14Å; V61-L65 WeakPolarHBondContact O-CB 3.47Å; V61-L65 WeakPolarHBondContact O-CG 3.19Å; V61-L65 PolarHBondContact O-N 3.4Å; V61-V73 HydrophobicContact CG1-CG1 4.24Å; V61-V110 HydrophobicContact CG2-CB 4.2Å; V61-V110 HydrophobicContact CG2-CG1 4.29Å; V61-V110 HydrophobicContact CG2-CG2 4.01Å; V61-L114 HydrophobicContact CG1-CD2 4.44Å; V61-I117 HydrophobicContact CG1-CD1 4.37Å
62G91.3Very high91.8Very high0 Ų033.6 Ų33.60%016%0.155CC..Hα-helixtrans-64.2-39.6-17900000112.5P59 I60 S66 K380 S384P59-G62 PolarHBondContact O-N 3.12Å; I60-G62 VanDerWaalsContact C-N 3.27Å; I60-G62 PolarHBondContact O-N 3.44Å; G62-S66 PolarHBondContact O-N 3.31Å; G62-K380 WeakPolarHBondContact CA-O 3.27Å; G62-S384 WeakPolarHBondContact CA-OG 3.45Å; G62-S384 PolarHBondContact N-OG 2.85Å
63E89.4Confident92.1Very high7 Ų731.4 Ų31.43%0.03314%0.144CC..Hα-helixtrans-68.9-43.4174.3-175.859.7-151.700111.4I60 V61 L65 S66 R67 F194 F247 K381I60-E63 PolarHBondContact O-N 3.4Å; V61-E63 VanDerWaalsContact C-N 3.32Å; V61-E63 PolarHBondContact O-N 2.75Å; E63-L65 VanDerWaalsContact C-N 3.33Å; E63-L65 PolarHBondContact O-N 2.75Å; E63-S66 WeakPolarHBondContact O-CB 3.33Å; E63-S66 PolarHBondContact O-N 3.44Å; E63-S66 VanDerWaalsContact O-N 3.17Å; E63-S66 PolarHBondContact O-OG 3.39Å; E63-R67 IonicContact OE1-CZ 3.23Å; E63-R67 VanDerWaalsContact OE1-CZ 3.23Å; E63-R67 IonicContact OE1-NE 2.79Å; E63-R67 PolarHBondContact OE1-NE 3.28Å; E63-R67 IonicContact OE1-NH2 2.83Å; E63-R67 PolarHBondContact OE1-NH2 3.03Å; E63-F194 HydrophobicContact CG-CD2 3.9Å; E63-F194 HydrophobicContact CG-CE2 3.53Å; E63-F194 WeakPolarHBondContact OE1-CD2 3.41Å; E63-F247 HydrophobicContact CB-CD2 4.18Å; E63-F247 HydrophobicContact CB-CE2 3.9Å; E63-F247 HydrophobicContact CG-CD2 4.38Å; E63-F247 HydrophobicContact CG-CE2 4.44Å; E63-K381 WeakPolarHBondContact OE2-CE 3.28Å; E63-K381 IonicContact OE2-NZ 3.23Å; E63-K381 PolarHBondContact OE2-NZ 3.31Å
64L91.9Very high92.2Very high56 Ų5631.3 Ų31.329%0.29314%0.143SC..Hα-helixtrans-59.5-43.1175-70.3174.3000111.4I60 V61 S66 R67 F68 V73I60-L64 HydrophobicContact CG2-CD1 4.04Å; I60-L64 VanDerWaalsContact O-CG 3.3Å; I60-L64 WeakPolarHBondContact O-CG 3.46Å; I60-L64 PolarHBondContact O-N 2.98Å; V61-L64 PolarHBondContact O-N 3.14Å; L64-S66 PolarHBondContact O-N 2.99Å; L64-R67 CarbonylContact O-C 3.58Å; L64-R67 PolarHBondContact O-N 3.09Å; L64-F68 HydrophobicContact CB-CD2 4.46Å; L64-F68 HydrophobicContact CD2-CD2 4.01Å; L64-F68 HydrophobicContact CD2-CE2 3.99Å; L64-F68 WeakPolarHBondContact O-CB 3.21Å; L64-F68 WeakPolarHBondContact O-CD2 3.43Å; L64-F68 PolarHBondContact O-N 3.24Å; L64-V73 HydrophobicContact CB-CG1 4.5Å; L64-V73 HydrophobicContact CB-CG2 3.96Å
65L91.4Very high92.4Very high3 Ų333 Ų332%0.01615%0.152CC..THydrogen-bonded Turntrans-73.3-9179.8-67.6173.4000114.7V61 E63 R67 I70 V73 L114 I117 K380V61-L65 HydrophobicContact CG1-CD1 3.67Å; V61-L65 HydrophobicContact CG1-CG 4.14Å; V61-L65 WeakPolarHBondContact O-CB 3.47Å; V61-L65 WeakPolarHBondContact O-CG 3.19Å; V61-L65 PolarHBondContact O-N 3.4Å; E63-L65 VanDerWaalsContact C-N 3.33Å; E63-L65 PolarHBondContact O-N 2.75Å; L65-R67 VanDerWaalsContact C-N 3.33Å; L65-I70 HydrophobicContact CD2-CB 3.83Å; L65-I70 HydrophobicContact CD2-CD1 4.5Å; L65-I70 HydrophobicContact CD2-CG1 3.72Å; L65-V73 HydrophobicContact CD2-CB 3.77Å; L65-V73 HydrophobicContact CD2-CG1 4.12Å; L65-V73 HydrophobicContact CD2-CG2 3.69Å; L65-V73 HydrophobicContact CG-CB 4.49Å; L65-V73 HydrophobicContact CG-CG1 4.36Å; L65-V73 HydrophobicContact CG-CG2 4.29Å; L65-L114 HydrophobicContact CD1-CD2 3.98Å; L65-L114 HydrophobicContact CD2-CD2 4.37Å; L65-I117 HydrophobicContact CD1-CD1 3.48Å; L65-I117 VanDerWaalsContact CD1-CD1 3.48Å; L65-I117 HydrophobicContact CD1-CG2 4.36Å; L65-K380 HydrophobicContact CB-CB 4.32Å; L65-K380 HydrophobicContact CB-CD 3.7Å; L65-K380 HydrophobicContact CD1-CD 4.49Å; L65-K380 PolarHBondContact O-NZ 3.39Å; L65-K380 VanDerWaalsContact O-NZ 3.15Å
66S86.8Confident92.7Very high22 Ų2235.2 Ų35.215%0.15417%0.17CC..THydrogen-bonded Turntrans-82.7-14.4167.878.70000112.6G62 E63 L64 V189 A190G62-S66 PolarHBondContact O-N 3.31Å; E63-S66 WeakPolarHBondContact O-CB 3.33Å; E63-S66 PolarHBondContact O-N 3.44Å; E63-S66 VanDerWaalsContact O-N 3.17Å; E63-S66 PolarHBondContact O-OG 3.39Å; L64-S66 PolarHBondContact O-N 2.99Å; S66-V189 WeakPolarHBondContact O-CA 3.16Å; S66-A190 PolarHBondContact O-N 3.49Å
67R85.9Confident93Very high63 Ų6332.6 Ų32.624%0.23816%0.157CC..THydrogen-bonded Turntrans-119.2-30.4-174.1-62.6178.7-174.5-83.3-10.9113.3E63 L64 L65 V189 S192 F194E63-R67 IonicContact OE1-CZ 3.23Å; E63-R67 VanDerWaalsContact OE1-CZ 3.23Å; E63-R67 IonicContact OE1-NE 2.79Å; E63-R67 PolarHBondContact OE1-NE 3.28Å; E63-R67 IonicContact OE1-NH2 2.83Å; E63-R67 PolarHBondContact OE1-NH2 3.03Å; L64-R67 CarbonylContact O-C 3.58Å; L64-R67 PolarHBondContact O-N 3.09Å; L65-R67 VanDerWaalsContact C-N 3.33Å; R67-V189 WeakPolarHBondContact O-CG1 3.42Å; R67-V189 WeakPolarHBondContact O-CG2 3.32Å; R67-S192 PolarHBondContact NH1-O 3.28Å; R67-S192 PolarHBondContact NH2-O 3.28Å; R67-F194 VanDerWaalsContact NH2-CA 3.29Å
68F89.9Confident93.2Very high111 Ų11132.5 Ų32.549%0.48716%0.156SC..SBendtrans-124.6149.3-175.5-58.3-73.4000110L64 V73L64-F68 HydrophobicContact CB-CD2 4.46Å; L64-F68 HydrophobicContact CD2-CD2 4.01Å; L64-F68 HydrophobicContact CD2-CE2 3.99Å; L64-F68 WeakPolarHBondContact O-CB 3.21Å; L64-F68 WeakPolarHBondContact O-CD2 3.43Å; L64-F68 PolarHBondContact O-N 3.24Å; F68-V73 HydrophobicContact CB-CG2 4.07Å
69K91.4Very high93.4Very high115 Ų11536.4 Ų36.450%0.518%0.176SC..  trans-60.9148.8172.3-65.1-171.2177.8-174.70110.8I71 Y72 V73 E186K69-I71 HydrophobicContact CB-CG2 3.89Å; K69-I71 PolarHBondContact O-N 2.69Å; K69-Y72 HydrophobicContact CB-CD2 3.74Å; K69-Y72 HydrophobicContact CB-CE2 3.94Å; K69-Y72 HydrophobicContact CD-CE2 4.12Å; K69-Y72 HydrophobicContact CG-CD2 4.39Å; K69-Y72 HydrophobicContact CG-CE2 4.17Å; K69-Y72 PolarHBondContact O-N 3.41Å; K69-Y72 VanDerWaalsContact O-N 3.12Å; K69-V73 PolarHBondContact O-N 3.34Å; K69-E186 WeakPolarHBondContact CA-OE2 3.46Å; K69-E186 WeakPolarHBondContact CB-OE2 3.25Å
70I93.7Very high93.8Very high3 Ų339.5 Ų39.52%0.01519%0.193CC..Hα-helixtrans-62.9-33.4-175.3-165.6165.5000112.4L65 Y72 V73 A74 L114 I117 V118 L121 F181 F183 E186L65-I70 HydrophobicContact CD2-CB 3.83Å; L65-I70 HydrophobicContact CD2-CD1 4.5Å; L65-I70 HydrophobicContact CD2-CG1 3.72Å; I70-Y72 VanDerWaalsContact C-N 3.32Å; I70-Y72 PolarHBondContact O-N 3.47Å; I70-V73 PolarHBondContact O-N 3.22Å; I70-A74 VanDerWaalsContact O-CB 3.25Å; I70-A74 WeakPolarHBondContact O-CB 3.46Å; I70-A74 PolarHBondContact O-N 3.15Å; I70-L114 HydrophobicContact CD1-CD2 3.9Å; I70-L114 HydrophobicContact CG1-CD2 3.64Å; I70-I117 HydrophobicContact CD1-CG2 4.27Å; I70-V118 HydrophobicContact CD1-CG2 3.65Å; I70-L121 HydrophobicContact CD1-CD1 3.68Å; I70-F181 HydrophobicContact CG1-CD2 4.5Å; I70-F181 HydrophobicContact CG2-CB 4.2Å; I70-F183 HydrophobicContact CD1-CE2 4.35Å; I70-F183 HydrophobicContact CG2-CD2 3.78Å; I70-F183 HydrophobicContact CG2-CE2 3.89Å; I70-E186 WeakPolarHBondContact CG2-OE1 3.49Å; I70-E186 PolarHBondContact N-OE2 2.87Å
71I94.9Very high94Very high16 Ų1637 Ų378%0.08218%0.18CC..Hα-helixtrans-56.4-44.1175.7-174.7170.5000111.9K69 A74 I75 V177 F181K69-I71 HydrophobicContact CB-CG2 3.89Å; K69-I71 PolarHBondContact O-N 2.69Å; I71-A74 PolarHBondContact O-N 2.92Å; I71-I75 HydrophobicContact CD1-CD1 4.39Å; I71-I75 HydrophobicContact CG1-CD1 3.72Å; I71-I75 HydrophobicContact CG1-CG1 4.42Å; I71-I75 WeakPolarHBondContact O-CB 3.41Å; I71-I75 VanDerWaalsContact O-CG1 3.23Å; I71-I75 WeakPolarHBondContact O-CG1 3.36Å; I71-I75 PolarHBondContact O-N 3.33Å; I71-V177 HydrophobicContact CG1-CG1 4.4Å; I71-F181 HydrophobicContact CB-CB 4.49Å
72Y95.2Very high94.2Very high141 Ų14137.7 Ų37.755%0.55319%0.185SC*.Hα-helixtrans-69.9-40.6-178.4-58.5-48.3000111.6K69 I70 A76K69-Y72 HydrophobicContact CB-CD2 3.74Å; K69-Y72 HydrophobicContact CB-CE2 3.94Å; K69-Y72 HydrophobicContact CD-CE2 4.12Å; K69-Y72 HydrophobicContact CG-CD2 4.39Å; K69-Y72 HydrophobicContact CG-CE2 4.17Å; K69-Y72 PolarHBondContact O-N 3.41Å; K69-Y72 VanDerWaalsContact O-N 3.12Å; I70-Y72 VanDerWaalsContact C-N 3.32Å; I70-Y72 PolarHBondContact O-N 3.47Å; Y72-A76 WeakPolarHBondContact O-CB 3.07Å; Y72-A76 PolarHBondContact O-N 3.22Å
73V95.9Very high94.5Very high8 Ų841.8 Ų41.85%0.04821%0.205CC..Hα-helixtrans-66.3-41.3176.7-179.20000110.7V61 L64 L65 F68 K69 I70 A76 G77 V110V61-V73 HydrophobicContact CG1-CG1 4.24Å; L64-V73 HydrophobicContact CB-CG1 4.5Å; L64-V73 HydrophobicContact CB-CG2 3.96Å; L65-V73 HydrophobicContact CD2-CB 3.77Å; L65-V73 HydrophobicContact CD2-CG1 4.12Å; L65-V73 HydrophobicContact CD2-CG2 3.69Å; L65-V73 HydrophobicContact CG-CB 4.49Å; L65-V73 HydrophobicContact CG-CG1 4.36Å; L65-V73 HydrophobicContact CG-CG2 4.29Å; F68-V73 HydrophobicContact CB-CG2 4.07Å; K69-V73 PolarHBondContact O-N 3.34Å; I70-V73 PolarHBondContact O-N 3.22Å; V73-A76 PolarHBondContact O-N 2.99Å; V73-G77 PolarHBondContact O-N 3.43Å; V73-V110 HydrophobicContact CG1-CG1 3.84Å; V73-V110 WeakPolarHBondContact O-CG1 3.3Å
74A97Very high95Very high0 Ų041.4 Ų41.40%020%0.204CC..Hα-helixtrans-63.9-46.4176.900000112.4I70 I71 G77 L78 L114 V177 F181I70-A74 VanDerWaalsContact O-CB 3.25Å; I70-A74 WeakPolarHBondContact O-CB 3.46Å; I70-A74 PolarHBondContact O-N 3.15Å; I71-A74 PolarHBondContact O-N 2.92Å; A74-G77 PolarHBondContact O-N 2.88Å; A74-L78 WeakPolarHBondContact O-CG 3.36Å; A74-L78 PolarHBondContact O-N 2.93Å; A74-L114 VanDerWaalsContact CA-CD1 3.44Å; A74-L114 HydrophobicContact CB-CD1 3.64Å; A74-V177 HydrophobicContact CB-CG1 3.7Å; A74-F181 HydrophobicContact CB-CD2 3.81Å; A74-F181 HydrophobicContact CB-CE2 4Å
75I97.8Very high95.2Very high37 Ų3738.8 Ų38.819%0.1919%0.19CC..Hα-helixtrans-63.2-43.3176.5-68.7168.3000110.4I71 G77 L78 L79 V177 I178I71-I75 HydrophobicContact CD1-CD1 4.39Å; I71-I75 HydrophobicContact CG1-CD1 3.72Å; I71-I75 HydrophobicContact CG1-CG1 4.42Å; I71-I75 WeakPolarHBondContact O-CB 3.41Å; I71-I75 VanDerWaalsContact O-CG1 3.23Å; I71-I75 WeakPolarHBondContact O-CG1 3.36Å; I71-I75 PolarHBondContact O-N 3.33Å; I75-G77 VanDerWaalsContact C-N 3.34Å; I75-G77 PolarHBondContact O-N 2.92Å; I75-L78 PolarHBondContact O-N 3.49Å; I75-L79 HydrophobicContact CG2-CD1 3.8Å; I75-L79 HydrophobicContact CG2-CG 4.13Å; I75-L79 WeakPolarHBondContact O-CB 3.48Å; I75-L79 VanDerWaalsContact O-CG 3.27Å; I75-L79 WeakPolarHBondContact O-CG 3.48Å; I75-L79 PolarHBondContact O-N 3.4Å; I75-V177 HydrophobicContact CG1-CG1 4.15Å; I75-I178 HydrophobicContact CD1-CD1 4.31Å; I75-I178 HydrophobicContact CD1-CG1 3.71Å; I75-I178 HydrophobicContact CG1-CG1 4.39Å
76A98Very high95.5Very high47 Ų4743.6 Ų43.639%0.38821%0.211SC..Hα-helixtrans-59.6-44.2176.300000111.9Y72 V73 L79 L80Y72-A76 WeakPolarHBondContact O-CB 3.07Å; Y72-A76 PolarHBondContact O-N 3.22Å; V73-A76 PolarHBondContact O-N 2.99Å; A76-L79 PolarHBondContact O-N 3.49Å; A76-L80 WeakPolarHBondContact O-CB 3.44Å; A76-L80 VanDerWaalsContact O-CG 3.31Å; A76-L80 WeakPolarHBondContact O-CG 3.14Å; A76-L80 PolarHBondContact O-N 3.32Å
77G97.9Very high96.1Very high0 Ų045 Ų450%022%0.216CC..Hα-helixtrans-61-45.7174.900000113.1V73 A74 I75 L80 F81 G107V73-G77 PolarHBondContact O-N 3.43Å; A74-G77 PolarHBondContact O-N 2.88Å; I75-G77 VanDerWaalsContact C-N 3.34Å; I75-G77 PolarHBondContact O-N 2.92Å; G77-L80 PolarHBondContact O-N 3.11Å; G77-F81 WeakPolarHBondContact O-CB 3.28Å; G77-F81 PolarHBondContact O-N 2.93Å; G77-G107 VanDerWaalsContact O-CA 3.23Å; G77-G107 WeakPolarHBondContact O-CA 3.29Å
78L98Very high96.6Very high0 Ų042 Ų420%020%0.204CC..Hα-helixtrans-63.7-40.2176.6-74.7168.5000112.2I15 A74 I75 F81 S82 L111 A173 I174 V177I15-L78 HydrophobicContact CG1-CD2 4.25Å; A74-L78 WeakPolarHBondContact O-CG 3.36Å; A74-L78 PolarHBondContact O-N 2.93Å; I75-L78 PolarHBondContact O-N 3.49Å; L78-F81 PolarHBondContact O-N 2.93Å; L78-S82 VanDerWaalsContact O-CB 3.31Å; L78-S82 WeakPolarHBondContact O-CB 3.11Å; L78-S82 PolarHBondContact O-N 2.9Å; L78-S82 PolarHBondContact O-OG 3.5Å; L78-L111 HydrophobicContact CD2-CD1 4.02Å; L78-L111 HydrophobicContact CD2-CD2 3.81Å; L78-L111 HydrophobicContact CG-CD2 3.78Å; L78-A173 HydrophobicContact CD1-CB 4.18Å; L78-A173 HydrophobicContact CD2-CB 3.84Å; L78-I174 HydrophobicContact CB-CD1 4.07Å; L78-I174 HydrophobicContact CB-CG1 3.58Å; L78-I174 HydrophobicContact CD1-CB 4.31Å; L78-I174 HydrophobicContact CD1-CG1 3.61Å; L78-I174 HydrophobicContact CG-CG1 4.14Å; L78-V177 HydrophobicContact CD1-CB 4.34Å; L78-V177 HydrophobicContact CD1-CG2 3.9Å
79L98.2Very high97Very high82 Ų8236.8 Ų36.843%0.42918%0.182SC..Hα-helixtrans-66.7-46176.6-73.2175.4000111.5I75 A76 F81 S82 I83 I174I75-L79 HydrophobicContact CG2-CD1 3.8Å; I75-L79 HydrophobicContact CG2-CG 4.13Å; I75-L79 WeakPolarHBondContact O-CB 3.48Å; I75-L79 VanDerWaalsContact O-CG 3.27Å; I75-L79 WeakPolarHBondContact O-CG 3.48Å; I75-L79 PolarHBondContact O-N 3.4Å; A76-L79 PolarHBondContact O-N 3.49Å; L79-F81 VanDerWaalsContact C-N 3.31Å; L79-F81 PolarHBondContact O-N 3.48Å; L79-S82 PolarHBondContact O-N 3.21Å; L79-I83 WeakPolarHBondContact O-CB 3.35Å; L79-I83 WeakPolarHBondContact O-CG1 3.48Å; L79-I83 PolarHBondContact O-N 3.39Å; L79-I174 HydrophobicContact CD2-CD1 4.05Å
80L98.3Very high97.3Very high67 Ų6735 Ų3535%0.35118%0.177SC..Hα-helixtrans-58.3-45.4175.1-74.7170.3000111.2A76 G77 S82 G84 I103 F106A76-L80 WeakPolarHBondContact O-CB 3.44Å; A76-L80 VanDerWaalsContact O-CG 3.31Å; A76-L80 WeakPolarHBondContact O-CG 3.14Å; A76-L80 PolarHBondContact O-N 3.32Å; G77-L80 PolarHBondContact O-N 3.11Å; L80-S82 PolarHBondContact O-N 2.95Å; L80-G84 PolarHBondContact O-N 2.83Å; L80-I103 HydrophobicContact CD2-CG2 4.32Å; L80-F106 HydrophobicContact CD1-CB 4.33Å
81F97.6Very high97.4Very high0 Ų034.9 Ų34.90%018%0.177CC..Hα-helixtrans-62.3-44.6176.7-169.2-81.9000111.9M18 E22 Y50 G77 L78 L79 S85 Q104 L111 N166M18-F81 HydrophobicContact CB-CE1 4Å; M18-F81 HydrophobicContact CB-CZ 3.98Å; M18-F81 HydrophobicContact CE-CD1 3.11Å; M18-F81 HydrophobicContact CE-CE1 3.28Å; M18-F81 HydrophobicContact CE-CG 3.96Å; M18-F81 HydrophobicContact CE-CZ 4.23Å; E22-F81 VanDerWaalsContact OE2-CE2 3.25Å; E22-F81 WeakPolarHBondContact OE2-CE2 3.47Å; E22-F81 VanDerWaalsContact OE2-CZ 3.27Å; E22-F81 WeakPolarHBondContact OE2-CZ 3.28Å; Y50-F81 HydrophobicContact CE2-CE2 4.5Å; G77-F81 WeakPolarHBondContact O-CB 3.28Å; G77-F81 PolarHBondContact O-N 2.93Å; L78-F81 PolarHBondContact O-N 2.93Å; L79-F81 VanDerWaalsContact C-N 3.31Å; L79-F81 PolarHBondContact O-N 3.48Å; F81-S85 WeakPolarHBondContact CD1-OG 3.3Å; F81-S85 VanDerWaalsContact CE1-OG 3.31Å; F81-S85 WeakPolarHBondContact CE1-OG 3.44Å; F81-S85 VanDerWaalsContact O-CB 3.32Å; F81-S85 WeakPolarHBondContact O-CB 3.48Å; F81-S85 PolarHBondContact O-N 3.43Å; F81-S85 PolarHBondContact O-OG 3.31Å; F81-Q104 HydrophobicContact CD2-CG 3.96Å; F81-Q104 HydrophobicContact CE2-CG 3.94Å; F81-Q104 HydrophobicContact CG-CG 4.32Å; F81-Q104 HydrophobicContact CZ-CG 4.27Å; F81-L111 HydrophobicContact CB-CD1 4.16Å; F81-L111 HydrophobicContact CD2-CD1 4.3Å; F81-L111 HydrophobicContact CG-CD1 4.26Å; F81-N166 HydrophobicContact CE1-CB 3.82Å
82S97.7Very high97.5Very high14 Ų1439.6 Ų39.610%0.09821%0.207CC..Hα-helixtrans-66-46.9-179.7-56.20000111.9L78 L79 L80 S85 F86 I167 A170L78-S82 VanDerWaalsContact O-CB 3.31Å; L78-S82 WeakPolarHBondContact O-CB 3.11Å; L78-S82 PolarHBondContact O-N 2.9Å; L78-S82 PolarHBondContact O-OG 3.5Å; L79-S82 PolarHBondContact O-N 3.21Å; L80-S82 PolarHBondContact O-N 2.95Å; S82-S85 PolarHBondContact O-N 2.91Å; S82-F86 WeakPolarHBondContact O-CB 3.45Å; S82-F86 PolarHBondContact O-N 3.41Å; S82-I167 WeakPolarHBondContact O-CD1 3.25Å; S82-A170 WeakPolarHBondContact OG-CB 3.21Å
83I98.4Very high97.6Very high85 Ų8536.2 Ų36.244%0.43620%0.198SC..Hα-helixtrans-62.4-46.5178-68.3165.4000109.6L79 S85 F86 M87 I103L79-I83 WeakPolarHBondContact O-CB 3.35Å; L79-I83 WeakPolarHBondContact O-CG1 3.48Å; L79-I83 PolarHBondContact O-N 3.39Å; I83-S85 PolarHBondContact O-N 3.47Å; I83-F86 PolarHBondContact O-N 3.24Å; I83-M87 HydrophobicContact CG2-CG 4.39Å; I83-M87 HydrophobicContact CG2-SD 3.87Å; I83-M87 VanDerWaalsContact O-CG 3.28Å; I83-M87 WeakPolarHBondContact O-CG 3.19Å; I83-M87 PolarHBondContact O-N 3.06Å; I83-I103 HydrophobicContact CG2-CG2 4.38Å
84G98.2Very high97.5Very high0 Ų036.9 Ų36.90%020%0.2CC..Hα-helixtrans-58.4-46.8175.200000112.3L80 F86 M87 C88L80-G84 PolarHBondContact O-N 2.83Å; G84-F86 VanDerWaalsContact C-N 3.35Å; G84-F86 PolarHBondContact O-N 3.28Å; G84-M87 PolarHBondContact O-N 3.46Å; G84-C88 WeakPolarHBondContact O-CB 3.27Å; G84-C88 PolarHBondContact O-N 3.48Å; G84-C88 PolarHBondContact O-SG 3.06Å
85S97.4Very high97.5Very high0 Ų041.4 Ų41.40%023%0.228CC..Hα-helixtrans-59.9-43.4176-57.90000112F81 S82 I83 C88 G89 Q104 F163F81-S85 WeakPolarHBondContact CD1-OG 3.3Å; F81-S85 VanDerWaalsContact CE1-OG 3.31Å; F81-S85 WeakPolarHBondContact CE1-OG 3.44Å; F81-S85 VanDerWaalsContact O-CB 3.32Å; F81-S85 WeakPolarHBondContact O-CB 3.48Å; F81-S85 PolarHBondContact O-N 3.43Å; F81-S85 PolarHBondContact O-OG 3.31Å; S82-S85 PolarHBondContact O-N 2.91Å; I83-S85 PolarHBondContact O-N 3.47Å; S85-C88 WeakPolarHBondContact O-CB 3.42Å; S85-C88 PolarHBondContact O-N 3.07Å; S85-G89 PolarHBondContact O-N 3.22Å; S85-Q104 PolarHBondContact OG-NE2 3.43Å; S85-F163 WeakPolarHBondContact O-CB 3.42Å
86F98.3Very high97.5Very high105 Ų10542.2 Ų42.246%0.46123%0.232SC..Hα-helixtrans-64.5-44.2178.8179.1-107.1000111.5S82 I83 G84 G89 L90 Y164 I167S82-F86 WeakPolarHBondContact O-CB 3.45Å; S82-F86 PolarHBondContact O-N 3.41Å; I83-F86 PolarHBondContact O-N 3.24Å; G84-F86 VanDerWaalsContact C-N 3.35Å; G84-F86 PolarHBondContact O-N 3.28Å; F86-G89 PolarHBondContact O-N 3.48Å; F86-L90 HydrophobicContact CD1-CD1 3.89Å; F86-L90 HydrophobicContact CE1-CD1 3.33Å; F86-L90 HydrophobicContact CE1-CG 4.3Å; F86-L90 HydrophobicContact CE2-CD1 4.37Å; F86-L90 HydrophobicContact CZ-CD1 3.62Å; F86-L90 HydrophobicContact CZ-CG 4.27Å; F86-L90 PolarHBondContact O-N 3.38Å; F86-Y164 HydrophobicContact CD2-CD1 4.36Å; F86-Y164 AromaticContact CD2-CE1 3.88Å; F86-Y164 HydrophobicContact CD2-CE1 3.88Å; F86-Y164 HydrophobicContact CE2-CE1 4.28Å; F86-I167 HydrophobicContact CB-CD1 3.96Å
87M98.3Very high97.5Very high51 Ų5140 Ų4025%0.25121%0.213SC..Hα-helixtrans-66.6-36176.3-66.2175.660.800112.3I83 G84 G89 L90 S91 S100 I103I83-M87 HydrophobicContact CG2-CG 4.39Å; I83-M87 HydrophobicContact CG2-SD 3.87Å; I83-M87 VanDerWaalsContact O-CG 3.28Å; I83-M87 WeakPolarHBondContact O-CG 3.19Å; I83-M87 PolarHBondContact O-N 3.06Å; G84-M87 PolarHBondContact O-N 3.46Å; M87-G89 VanDerWaalsContact C-N 3.34Å; M87-G89 PolarHBondContact O-N 3.31Å; M87-L90 CarbonylContact O-C 3.57Å; M87-L90 PolarHBondContact O-N 3.32Å; M87-L90 VanDerWaalsContact O-N 3.15Å; M87-S91 PolarHBondContact O-N 3.32Å; M87-S91 VanDerWaalsContact O-N 3.15Å; M87-S91 PolarHBondContact O-OG 2.9Å; M87-S100 VanDerWaalsContact C-OG 3.31Å; M87-S100 WeakPolarHBondContact CB-OG 3.11Å; M87-S100 PolarHBondContact O-OG 3.1Å; M87-I103 HydrophobicContact CE-CD1 3.75Å; M87-I103 HydrophobicContact SD-CD1 3.61Å
88C97.5Very high97.5Very high0 Ų041.1 Ų41.10%022%0.219CC..Hα-helixtrans-60.1-44.8172.2-72.60000111G84 S85 L90 S91 L97 S100 Q104 F163G84-C88 WeakPolarHBondContact O-CB 3.27Å; G84-C88 PolarHBondContact O-N 3.48Å; G84-C88 PolarHBondContact O-SG 3.06Å; S85-C88 WeakPolarHBondContact O-CB 3.42Å; S85-C88 PolarHBondContact O-N 3.07Å; C88-L90 VanDerWaalsContact C-N 3.25Å; C88-L90 PolarHBondContact O-N 3.45Å; C88-S91 WeakPolarHBondContact CA-OG 3.45Å; C88-S91 VanDerWaalsContact O-CB 3.25Å; C88-S91 WeakPolarHBondContact O-CB 3.36Å; C88-S91 PolarHBondContact O-N 2.71Å; C88-S91 VanDerWaalsContact O-N 3.16Å; C88-S91 PolarHBondContact O-OG 3.5Å; C88-L97 HydrophobicContact CB-CD1 3.88Å; C88-S100 WeakPolarHBondContact SG-CB 3.24Å; C88-Q104 PolarHBondContact SG-OE1 3.37Å; C88-Q104 VanDerWaalsContact SG-OE1 3.36Å; C88-F163 HydrophobicContact CB-CB 3.95Å; C88-F163 HydrophobicContact CB-CD1 3.22Å; C88-F163 HydrophobicContact CB-CD2 3.88Å; C88-F163 HydrophobicContact CB-CE1 3.48Å; C88-F163 VanDerWaalsContact CB-CE1 3.48Å; C88-F163 HydrophobicContact CB-CE2 4.13Å; C88-F163 HydrophobicContact CB-CG 3.41Å; C88-F163 VanDerWaalsContact CB-CG 3.41Å; C88-F163 HydrophobicContact CB-CZ 3.93Å
89G97.1Very high97.5Very high2 Ų245.5 Ų45.52%0.02124%0.242CC..Hα-helixtrans-66.5-23.4175.600000114S85 F86 M87 H160 Y164S85-G89 PolarHBondContact O-N 3.22Å; F86-G89 PolarHBondContact O-N 3.48Å; M87-G89 VanDerWaalsContact C-N 3.34Å; M87-G89 PolarHBondContact O-N 3.31Å; G89-H160 WeakPolarHBondContact O-CB 3.34Å; G89-H160 PolarHBondContact O-CD2 3.39Å; G89-Y164 VanDerWaalsContact C-CZ 3.4Å; G89-Y164 PolarHBondContact O-OH 3.43Å
90L97.4Very high97.5Very high77 Ų7741.6 Ų41.640%0.40322%0.221SC..THydrogen-bonded Turntrans-88.8-0.9174-72.2177.2000113.9F86 M87 C88 T92 M96 Y164F86-L90 HydrophobicContact CD1-CD1 3.89Å; F86-L90 HydrophobicContact CE1-CD1 3.33Å; F86-L90 HydrophobicContact CE1-CG 4.3Å; F86-L90 HydrophobicContact CE2-CD1 4.37Å; F86-L90 HydrophobicContact CZ-CD1 3.62Å; F86-L90 HydrophobicContact CZ-CG 4.27Å; F86-L90 PolarHBondContact O-N 3.38Å; M87-L90 CarbonylContact O-C 3.57Å; M87-L90 PolarHBondContact O-N 3.32Å; M87-L90 VanDerWaalsContact O-N 3.15Å; C88-L90 VanDerWaalsContact C-N 3.25Å; C88-L90 PolarHBondContact O-N 3.45Å; L90-T92 PolarHBondContact O-N 2.84Å; L90-M96 HydrophobicContact CB-CE 3.78Å; L90-M96 WeakPolarHBondContact O-CE 3.35Å; L90-Y164 VanDerWaalsContact CD2-OH 3.31Å; L90-Y164 WeakPolarHBondContact CD2-OH 3.25Å; L90-Y164 PolarHBondContact N-OH 3.35Å
91S97.4Very high97.4Very high0 Ų038.5 Ų38.50%021%0.205CC..  trans-72.5112.8-167.9-690000112.5M87 C88 L97 H160M87-S91 PolarHBondContact O-N 3.32Å; M87-S91 VanDerWaalsContact O-N 3.15Å; M87-S91 PolarHBondContact O-OG 2.9Å; C88-S91 WeakPolarHBondContact CA-OG 3.45Å; C88-S91 VanDerWaalsContact O-CB 3.25Å; C88-S91 WeakPolarHBondContact O-CB 3.36Å; C88-S91 PolarHBondContact O-N 2.71Å; C88-S91 VanDerWaalsContact O-N 3.16Å; C88-S91 PolarHBondContact O-OG 3.5Å; S91-L97 VanDerWaalsContact OG-CA 3.28Å; S91-L97 WeakPolarHBondContact OG-CA 3.49Å; S91-L97 PolarHBondContact OG-N 3.46Å; S91-H160 PolarHBondContact O-NE2 3.23Å
92T96.3Very high97.4Very high116 Ų11640.7 Ų40.771%0.71222%0.218SC*.  trans-95.3-6.4178.156.60000113.9L90L90-T92 PolarHBondContact O-N 2.84Å
93N96.2Very high97.4Very high69 Ų6942.1 Ų42.137%0.36922%0.224SC..SBendtrans-147160.4176.764.380.5000110.2T95 M96 L97N93-T95 VanDerWaalsContact C-N 3.35Å; N93-T95 PolarHBondContact O-N 3.41Å; N93-T95 WeakPolarHBondContact OD1-CB 3.49Å; N93-T95 PolarHBondContact OD1-N 2.86Å; N93-M96 PolarHBondContact O-N 3Å; N93-M96 PolarHBondContact OD1-N 2.77Å; N93-L97 PolarHBondContact O-N 3.15Å
94F95Very high97.3Very high22 Ų2238 Ų3810%0.09620%0.203CC..Hα-helixtrans-61.6-40.8-175-168.6-113.1000113.1L37 A39 L42 I43 L45 I46 M96 L97 I98L37-F94 HydrophobicContact CB-CB 4.25Å; A39-F94 HydrophobicContact CB-CD1 4.38Å; A39-F94 HydrophobicContact CB-CD2 3.37Å; A39-F94 HydrophobicContact CB-CE1 4.48Å; A39-F94 HydrophobicContact CB-CE2 3.48Å; A39-F94 VanDerWaalsContact CB-CE2 3.48Å; A39-F94 HydrophobicContact CB-CG 3.85Å; A39-F94 HydrophobicContact CB-CZ 4.07Å; L42-F94 HydrophobicContact CB-CD1 4.45Å; L42-F94 HydrophobicContact CB-CE1 3.68Å; L42-F94 HydrophobicContact CB-CZ 4.21Å; L42-F94 WeakPolarHBondContact O-CZ 3.26Å; I43-F94 HydrophobicContact CD1-CE2 4.26Å; L45-F94 HydrophobicContact CB-CE1 4.4Å; L45-F94 HydrophobicContact CB-CZ 4.25Å; L45-F94 HydrophobicContact CD2-CE1 4.45Å; I46-F94 HydrophobicContact CD1-CE2 3.83Å; I46-F94 HydrophobicContact CG1-CE2 3.58Å; I46-F94 HydrophobicContact CG1-CZ 4.03Å; F94-M96 PolarHBondContact O-N 3.16Å; F94-L97 WeakPolarHBondContact O-CB 3.34Å; F94-L97 PolarHBondContact O-N 3.43Å; F94-L97 VanDerWaalsContact O-N 3.15Å; F94-I98 HydrophobicContact CD1-CG1 4.06Å; F94-I98 HydrophobicContact CE1-CD1 3.94Å; F94-I98 HydrophobicContact CE1-CG1 3.7Å; F94-I98 HydrophobicContact CE2-CD1 4.13Å; F94-I98 HydrophobicContact CE2-CG1 4.43Å; F94-I98 HydrophobicContact CZ-CD1 3.63Å; F94-I98 HydrophobicContact CZ-CG1 3.91Å; F94-I98 WeakPolarHBondContact O-CG1 3.31Å; F94-I98 PolarHBondContact O-N 3.36Å
95T96.5Very high97.2Very high95 Ų9538 Ų3858%0.58320%0.203SC*.Hα-helixtrans-61-44.3179.7-54.40000111.9N93 L97 I98 I99N93-T95 VanDerWaalsContact C-N 3.35Å; N93-T95 PolarHBondContact O-N 3.41Å; N93-T95 WeakPolarHBondContact OD1-CB 3.49Å; N93-T95 PolarHBondContact OD1-N 2.86Å; T95-L97 VanDerWaalsContact C-N 3.31Å; T95-L97 PolarHBondContact O-N 3.08Å; T95-I98 PolarHBondContact O-N 3.3Å; T95-I99 HydrophobicContact CG2-CD1 4.14Å; T95-I99 WeakPolarHBondContact O-CG1 3.41Å; T95-I99 PolarHBondContact O-N 3.26Å
96M98.2Very high97.2Very high55 Ų5541.6 Ų41.627%0.27122%0.219SC..Hα-helixtrans-60.5-42175.4-176.9173.5171.100111.2L90 N93 F94 I98 I99 S100L90-M96 HydrophobicContact CB-CE 3.78Å; L90-M96 WeakPolarHBondContact O-CE 3.35Å; N93-M96 PolarHBondContact O-N 3Å; N93-M96 PolarHBondContact OD1-N 2.77Å; F94-M96 PolarHBondContact O-N 3.16Å; M96-I98 PolarHBondContact O-N 3.15Å; M96-I99 PolarHBondContact O-N 3.03Å; M96-S100 WeakPolarHBondContact O-CB 3.31Å; M96-S100 PolarHBondContact O-N 3.27Å; M96-S100 PolarHBondContact O-OG 2.88Å
97L97.4Very high97.2Very high0 Ų036.6 Ų36.60%020%0.197CC..Hα-helixtrans-61.7-43.5176.5-176.160.1000111.5I33 L37 I46 C88 S91 N93 F94 T95 S100 R101 W159 F163I33-L97 HydrophobicContact CG2-CD2 3.78Å; L37-L97 HydrophobicContact CD1-CB 4.08Å; L37-L97 HydrophobicContact CD1-CD2 3.6Å; L37-L97 HydrophobicContact CD1-CG 4.46Å; I46-L97 HydrophobicContact CD1-CD2 3.59Å; I46-L97 HydrophobicContact CG1-CD2 4.04Å; C88-L97 HydrophobicContact CB-CD1 3.88Å; S91-L97 VanDerWaalsContact OG-CA 3.28Å; S91-L97 WeakPolarHBondContact OG-CA 3.49Å; S91-L97 PolarHBondContact OG-N 3.46Å; N93-L97 PolarHBondContact O-N 3.15Å; F94-L97 WeakPolarHBondContact O-CB 3.34Å; F94-L97 PolarHBondContact O-N 3.43Å; F94-L97 VanDerWaalsContact O-N 3.15Å; T95-L97 VanDerWaalsContact C-N 3.31Å; T95-L97 PolarHBondContact O-N 3.08Å; L97-S100 WeakPolarHBondContact O-CB 3.47Å; L97-S100 PolarHBondContact O-N 3.02Å; L97-R101 WeakPolarHBondContact O-CB 3.37Å; L97-R101 VanDerWaalsContact O-CG 3.3Å; L97-R101 WeakPolarHBondContact O-CG 3.44Å; L97-R101 PolarHBondContact O-N 3.1Å; L97-W159 HydrophobicContact CD1-CZ3 4.32Å; L97-W159 HydrophobicContact CD2-CH2 4.41Å; L97-W159 HydrophobicContact CD2-CZ3 4.47Å; L97-F163 HydrophobicContact CD1-CE2 4.2Å; L97-F163 HydrophobicContact CD1-CZ 3.92Å
98I97Very high97Very high23 Ų2334.1 Ų34.112%0.11819%0.185CC..Hα-helixtrans-63.2-46.1178.1-65-51.5000111.9L45 I46 A49 F94 T95 M96 S100 R101 V102L45-I98 HydrophobicContact CB-CD1 3.93Å; L45-I98 HydrophobicContact CD2-CD1 4.21Å; L45-I98 HydrophobicContact CD2-CG1 4.07Å; L45-I98 HydrophobicContact CD2-CG2 4.15Å; L45-I98 HydrophobicContact CG-CD1 3.86Å; L45-I98 HydrophobicContact CG-CG1 4.26Å; L45-I98 HydrophobicContact CG-CG2 4.3Å; I46-I98 HydrophobicContact CB-CD1 4.47Å; I46-I98 HydrophobicContact CG1-CD1 3.96Å; A49-I98 HydrophobicContact CB-CG2 3.82Å; F94-I98 HydrophobicContact CD1-CG1 4.06Å; F94-I98 HydrophobicContact CE1-CD1 3.94Å; F94-I98 HydrophobicContact CE1-CG1 3.7Å; F94-I98 HydrophobicContact CE2-CD1 4.13Å; F94-I98 HydrophobicContact CE2-CG1 4.43Å; F94-I98 HydrophobicContact CZ-CD1 3.63Å; F94-I98 HydrophobicContact CZ-CG1 3.91Å; F94-I98 WeakPolarHBondContact O-CG1 3.31Å; F94-I98 PolarHBondContact O-N 3.36Å; T95-I98 PolarHBondContact O-N 3.3Å; M96-I98 PolarHBondContact O-N 3.15Å; I98-S100 VanDerWaalsContact C-N 3.28Å; I98-S100 PolarHBondContact O-N 3.12Å; I98-R101 WeakPolarHBondContact O-CB 3.23Å; I98-R101 PolarHBondContact O-N 3.05Å; I98-V102 WeakPolarHBondContact O-CG2 3.4Å; I98-V102 PolarHBondContact O-N 3.43Å
99I98.1Very high96.9Very high93 Ų9334.1 Ų34.148%0.47719%0.185SC..Hα-helixtrans-60.4-42.5176.5-66.4168000110.3T95 M96 R101 V102 I103T95-I99 HydrophobicContact CG2-CD1 4.14Å; T95-I99 WeakPolarHBondContact O-CG1 3.41Å; T95-I99 PolarHBondContact O-N 3.26Å; M96-I99 PolarHBondContact O-N 3.03Å; I99-R101 VanDerWaalsContact C-N 3.35Å; I99-R101 PolarHBondContact O-N 2.75Å; I99-V102 WeakPolarHBondContact O-CB 3.46Å; I99-V102 PolarHBondContact O-N 3.05Å; I99-I103 HydrophobicContact CG2-CD1 4.3Å; I99-I103 WeakPolarHBondContact O-CG1 3.48Å; I99-I103 PolarHBondContact O-N 3.09Å; I99-I103 VanDerWaalsContact O-N 3.14Å
100S98.2Very high96.9Very high0 Ų034.6 Ų34.60%019%0.187CC..Hα-helixtrans-63.2-41178.4-54.10000111.9M87 C88 M96 L97 I98 V102 I103 Q104M87-S100 VanDerWaalsContact C-OG 3.31Å; M87-S100 WeakPolarHBondContact CB-OG 3.11Å; M87-S100 PolarHBondContact O-OG 3.1Å; C88-S100 WeakPolarHBondContact SG-CB 3.24Å; M96-S100 WeakPolarHBondContact O-CB 3.31Å; M96-S100 PolarHBondContact O-N 3.27Å; M96-S100 PolarHBondContact O-OG 2.88Å; L97-S100 WeakPolarHBondContact O-CB 3.47Å; L97-S100 PolarHBondContact O-N 3.02Å; I98-S100 VanDerWaalsContact C-N 3.28Å; I98-S100 PolarHBondContact O-N 3.12Å; S100-V102 VanDerWaalsContact C-N 3.34Å; S100-V102 PolarHBondContact O-N 3.16Å; S100-I103 PolarHBondContact O-N 3.23Å; S100-Q104 WeakPolarHBondContact O-CB 3.47Å; S100-Q104 PolarHBondContact O-N 2.86Å
101R96.9Very high96.7Very high1 Ų131 Ų310%0.00417%0.168CC..Hα-helixtrans-62.7-37.1174.1-76.4-58.7-155.1136.119.3113.2E22 I46 L97 I98 I99 Q104 G105E22-R101 IonicContact OE1-CZ 3.64Å; E22-R101 IonicContact OE1-NH1 2.62Å; E22-R101 PolarHBondContact OE1-NH1 3.05Å; I46-R101 HydrophobicContact CG2-CG 4.31Å; L97-R101 WeakPolarHBondContact O-CB 3.37Å; L97-R101 VanDerWaalsContact O-CG 3.3Å; L97-R101 WeakPolarHBondContact O-CG 3.44Å; L97-R101 PolarHBondContact O-N 3.1Å; I98-R101 WeakPolarHBondContact O-CB 3.23Å; I98-R101 PolarHBondContact O-N 3.05Å; I99-R101 VanDerWaalsContact C-N 3.35Å; I99-R101 PolarHBondContact O-N 2.75Å; R101-Q104 PolarHBondContact O-N 2.85Å; R101-G105 PolarHBondContact O-N 3.29Å
102V97.7Very high96.4Very high47 Ų4731.6 Ų31.629%0.28517%0.171SC..Hα-helixtrans-61.4-50.3173.5170.20000110.1A49 A53 I98 I99 S100 Q104 G105 F106A49-V102 HydrophobicContact CB-CG2 3.89Å; A53-V102 HydrophobicContact CB-CB 4.39Å; A53-V102 HydrophobicContact CB-CG1 4.01Å; A53-V102 WeakPolarHBondContact CB-O 3.05Å; I98-V102 WeakPolarHBondContact O-CG2 3.4Å; I98-V102 PolarHBondContact O-N 3.43Å; I99-V102 WeakPolarHBondContact O-CB 3.46Å; I99-V102 PolarHBondContact O-N 3.05Å; S100-V102 VanDerWaalsContact C-N 3.34Å; S100-V102 PolarHBondContact O-N 3.16Å; V102-Q104 VanDerWaalsContact C-N 3.31Å; V102-Q104 PolarHBondContact O-N 3.42Å; V102-G105 PolarHBondContact O-N 3.05Å; V102-F106 HydrophobicContact CG1-CD2 3.89Å; V102-F106 HydrophobicContact CG1-CE2 3.54Å; V102-F106 WeakPolarHBondContact O-CD2 3.36Å; V102-F106 PolarHBondContact O-N 2.7Å
103I98.4Very high96.3Very high43 Ų4326.1 Ų26.122%0.22114%0.138CC..Hα-helixtrans-59.2-44.7178.8-62.8167.4000110.7L80 I83 M87 I99 S100 F106 G107L80-I103 HydrophobicContact CD2-CG2 4.32Å; I83-I103 HydrophobicContact CG2-CG2 4.38Å; M87-I103 HydrophobicContact CE-CD1 3.75Å; M87-I103 HydrophobicContact SD-CD1 3.61Å; I99-I103 HydrophobicContact CG2-CD1 4.3Å; I99-I103 WeakPolarHBondContact O-CG1 3.48Å; I99-I103 PolarHBondContact O-N 3.09Å; I99-I103 VanDerWaalsContact O-N 3.14Å; S100-I103 PolarHBondContact O-N 3.23Å; I103-F106 PolarHBondContact O-N 3.11Å; I103-G107 PolarHBondContact O-N 3.25Å
104Q96.8Very high96.2Very high0 Ų022.8 Ų22.80%012%0.12CC..Hα-helixtrans-63-42.8178.2-163.6179.213.300112.1E22 Y50 F81 S85 C88 S100 R101 V102 F106 G107 S108E22-Q104 PolarHBondContact OE1-NE2 3.25Å; E22-Q104 PolarHBondContact OE1-OE1 2.9Å; Y50-Q104 HydrophobicContact CD2-CB 4.34Å; Y50-Q104 HydrophobicContact CD2-CG 4.45Å; Y50-Q104 HydrophobicContact CE2-CG 4.2Å; F81-Q104 HydrophobicContact CD2-CG 3.96Å; F81-Q104 HydrophobicContact CE2-CG 3.94Å; F81-Q104 HydrophobicContact CG-CG 4.32Å; F81-Q104 HydrophobicContact CZ-CG 4.27Å; S85-Q104 PolarHBondContact OG-NE2 3.43Å; C88-Q104 PolarHBondContact SG-OE1 3.37Å; C88-Q104 VanDerWaalsContact SG-OE1 3.36Å; S100-Q104 WeakPolarHBondContact O-CB 3.47Å; S100-Q104 PolarHBondContact O-N 2.86Å; R101-Q104 PolarHBondContact O-N 2.85Å; V102-Q104 VanDerWaalsContact C-N 3.31Å; V102-Q104 PolarHBondContact O-N 3.42Å; Q104-F106 PolarHBondContact O-N 3.35Å; Q104-G107 PolarHBondContact O-N 3.15Å; Q104-G107 VanDerWaalsContact O-N 3.17Å; Q104-S108 PolarHBondContact O-N 3.42Å
105G96.1Very high96.1Very high0 Ų022 Ų220%012%0.117CC..Hα-helixtrans-62.8-39.7177.500000112.6Y50 L54 R101 V102 G107 S108 G109Y50-G105 VanDerWaalsContact CD2-CA 3.44Å; Y50-G105 WeakPolarHBondContact O-CA 3.48Å; L54-G105 WeakPolarHBondContact CA-O 3.31Å; L54-G105 WeakPolarHBondContact CB-O 3.32Å; L54-G105 PolarHBondContact N-O 3.04Å; R101-G105 PolarHBondContact O-N 3.29Å; V102-G105 PolarHBondContact O-N 3.05Å; G105-G107 VanDerWaalsContact C-N 3.31Å; G105-G107 PolarHBondContact O-N 2.67Å; G105-S108 PolarHBondContact O-N 3.34Å; G105-G109 PolarHBondContact O-N 2.88Å
106F97.3Very high95.9Very high74 Ų7418.3 Ų18.333%0.3259%0.093SC..Hα-helixtrans-57.3-45.6172-83.3-71000111.8A53 I56 A57 L80 V102 I103 Q104 G109 V110A53-F106 HydrophobicContact CB-CD2 3.86Å; A53-F106 HydrophobicContact CB-CE2 4.02Å; A53-F106 HydrophobicContact CB-CG 4.19Å; A53-F106 HydrophobicContact CB-CZ 4.49Å; I56-F106 HydrophobicContact CB-CE1 4.21Å; I56-F106 HydrophobicContact CG2-CE1 3.69Å; I56-F106 HydrophobicContact CG2-CZ 4.15Å; A57-F106 HydrophobicContact CB-CD1 3.85Å; A57-F106 WeakPolarHBondContact CB-O 3.38Å; L80-F106 HydrophobicContact CD1-CB 4.33Å; V102-F106 HydrophobicContact CG1-CD2 3.89Å; V102-F106 HydrophobicContact CG1-CE2 3.54Å; V102-F106 WeakPolarHBondContact O-CD2 3.36Å; V102-F106 PolarHBondContact O-N 2.7Å; I103-F106 PolarHBondContact O-N 3.11Å; Q104-F106 PolarHBondContact O-N 3.35Å; F106-G109 PolarHBondContact O-N 3.45Å; F106-V110 WeakPolarHBondContact O-CG2 3.46Å; F106-V110 PolarHBondContact O-N 3.25Å
107G97.3Very high95.8Very high0 Ų015.7 Ų15.70%08%0.08CC..Hα-helixtrans-59.2-49.8174.400000111.9G77 I103 Q104 G105 G109 V110 L111G77-G107 VanDerWaalsContact O-CA 3.23Å; G77-G107 WeakPolarHBondContact O-CA 3.29Å; I103-G107 PolarHBondContact O-N 3.25Å; Q104-G107 PolarHBondContact O-N 3.15Å; Q104-G107 VanDerWaalsContact O-N 3.17Å; G105-G107 VanDerWaalsContact C-N 3.31Å; G105-G107 PolarHBondContact O-N 2.67Å; G107-G109 VanDerWaalsContact C-N 3.33Å; G107-G109 PolarHBondContact O-N 3.36Å; G107-V110 WeakPolarHBondContact O-CB 3.3Å; G107-V110 PolarHBondContact O-N 2.8Å; G107-V110 VanDerWaalsContact O-N 3.12Å; G107-L111 VanDerWaalsContact O-CG 3.3Å; G107-L111 WeakPolarHBondContact O-CG 3.48Å; G107-L111 PolarHBondContact O-N 3.34Å
108S95Very high95.7Very high0 Ų015.7 Ų15.70%08%0.08CC..Hα-helixtrans-61.9-36.9-178.5-1720000113.2S19 Y50 L54 Q104 G105 V110 L111 M112S19-S108 WeakPolarHBondContact CB-OG 3.28Å; S19-S108 PolarHBondContact OG-OG 3.26Å; Y50-S108 WeakPolarHBondContact OH-CB 3.17Å; Y50-S108 PolarHBondContact OH-OG 3.47Å; L54-S108 VanDerWaalsContact CD1-OG 3.3Å; L54-S108 WeakPolarHBondContact CD1-OG 3.41Å; Q104-S108 PolarHBondContact O-N 3.42Å; G105-S108 PolarHBondContact O-N 3.34Å; S108-V110 PolarHBondContact O-N 3.1Å; S108-L111 WeakPolarHBondContact O-CB 3.39Å; S108-L111 PolarHBondContact O-N 3.46Å; S108-M112 WeakPolarHBondContact O-CB 3.33Å; S108-M112 WeakPolarHBondContact O-CG 3.28Å; S108-M112 PolarHBondContact O-N 3.47Å
109G94.7Very high95.6Very high0 Ų014.6 Ų14.60%08%0.075CC..Hα-helixtrans-65-38.9174.800000112.6N58 G105 F106 G107 L111 M112 S113N58-G109 WeakPolarHBondContact OD1-CA 3.3Å; N58-G109 PolarHBondContact OD1-O 3.24Å; G105-G109 PolarHBondContact O-N 2.88Å; F106-G109 PolarHBondContact O-N 3.45Å; G107-G109 VanDerWaalsContact C-N 3.33Å; G107-G109 PolarHBondContact O-N 3.36Å; G109-L111 PolarHBondContact O-N 3.4Å; G109-M112 PolarHBondContact O-N 3.28Å; G109-S113 PolarHBondContact O-N 3.35Å; G109-S113 VanDerWaalsContact O-N 3.1Å; G109-S113 PolarHBondContact O-OG 3.33Å
110V96.1Very high95.4Very high12 Ų1212.5 Ų12.57%0.0736%0.062CC..Hα-helixtrans-59.8-49.3172.4176.90000111V61 V73 F106 G107 S108 M112 S113 L114V61-V110 HydrophobicContact CG2-CB 4.2Å; V61-V110 HydrophobicContact CG2-CG1 4.29Å; V61-V110 HydrophobicContact CG2-CG2 4.01Å; V73-V110 HydrophobicContact CG1-CG1 3.84Å; V73-V110 WeakPolarHBondContact O-CG1 3.3Å; F106-V110 WeakPolarHBondContact O-CG2 3.46Å; F106-V110 PolarHBondContact O-N 3.25Å; G107-V110 WeakPolarHBondContact O-CB 3.3Å; G107-V110 PolarHBondContact O-N 2.8Å; G107-V110 VanDerWaalsContact O-N 3.12Å; S108-V110 PolarHBondContact O-N 3.1Å; V110-M112 PolarHBondContact O-N 3.38Å; V110-S113 PolarHBondContact O-N 3.22Å; V110-L114 HydrophobicContact CG1-CD1 3.9Å; V110-L114 HydrophobicContact CG1-CG 4.46Å; V110-L114 VanDerWaalsContact O-CG 3.26Å; V110-L114 WeakPolarHBondContact O-CG 3.46Å; V110-L114 PolarHBondContact O-N 3.48Å
111L94.7Very high95.1Very high0 Ų013.4 Ų13.40%07%0.067CC..Hα-helixtrans-60.7-42.9-179.7-70.1-171.7000113I15 L78 F81 G107 S108 G109 L114 S115I15-L111 HydrophobicContact CD1-CD2 4.49Å; I15-L111 HydrophobicContact CG1-CD2 4.29Å; I15-L111 HydrophobicContact CG2-CB 3.64Å; I15-L111 HydrophobicContact CG2-CD1 4.36Å; I15-L111 HydrophobicContact CG2-CD2 3.98Å; I15-L111 HydrophobicContact CG2-CG 4.15Å; L78-L111 HydrophobicContact CD2-CD1 4.02Å; L78-L111 HydrophobicContact CD2-CD2 3.81Å; L78-L111 HydrophobicContact CG-CD2 3.78Å; F81-L111 HydrophobicContact CB-CD1 4.16Å; F81-L111 HydrophobicContact CD2-CD1 4.3Å; F81-L111 HydrophobicContact CG-CD1 4.26Å; G107-L111 VanDerWaalsContact O-CG 3.3Å; G107-L111 WeakPolarHBondContact O-CG 3.48Å; G107-L111 PolarHBondContact O-N 3.34Å; S108-L111 WeakPolarHBondContact O-CB 3.39Å; S108-L111 PolarHBondContact O-N 3.46Å; G109-L111 PolarHBondContact O-N 3.4Å; L111-L114 PolarHBondContact O-N 3.44Å; L111-S115 PolarHBondContact O-N 2.98Å
112M91.4Very high95Very high14 Ų1414.6 Ų14.67%0.0698%0.077CC..Hα-helixtrans-67-42.3178.8-74.3-166.871.400112.1L54 S108 G109 V110 L114 S115 W139 N391L54-M112 HydrophobicContact CD1-CG 4.35Å; L54-M112 HydrophobicContact CD1-SD 3.63Å; L54-M112 HydrophobicContact CD2-SD 4.46Å; S108-M112 WeakPolarHBondContact O-CB 3.33Å; S108-M112 WeakPolarHBondContact O-CG 3.28Å; S108-M112 PolarHBondContact O-N 3.47Å; G109-M112 PolarHBondContact O-N 3.28Å; V110-M112 PolarHBondContact O-N 3.38Å; M112-L114 VanDerWaalsContact C-N 3.34Å; M112-L114 PolarHBondContact O-N 2.84Å; M112-S115 WeakPolarHBondContact O-CB 3.23Å; M112-S115 PolarHBondContact O-N 3.39Å; M112-S115 PolarHBondContact O-OG 3.44Å; M112-W139 HydrophobicContact CE-CZ2 4.06Å; M112-N391 WeakPolarHBondContact CE-OD1 3.39Å; M112-N391 PolarHBondContact SD-OD1 3.07Å
113S93.6Very high94.9Very high0 Ų012.9 Ų12.90%07%0.066CC..Hα-helixtrans-60.7-43.6172.4-73.30000111.7N58 G109 V110 S115 Q116 I117N58-S113 WeakPolarHBondContact CA-OG 3.36Å; N58-S113 PolarHBondContact O-OG 3Å; N58-S113 PolarHBondContact OD1-OG 2.83Å; G109-S113 PolarHBondContact O-N 3.35Å; G109-S113 VanDerWaalsContact O-N 3.1Å; G109-S113 PolarHBondContact O-OG 3.33Å; V110-S113 PolarHBondContact O-N 3.22Å; S113-S115 VanDerWaalsContact C-N 3.28Å; S113-S115 PolarHBondContact O-N 3.39Å; S113-Q116 PolarHBondContact O-N 3.3Å; S113-I117 WeakPolarHBondContact O-CG1 3.48Å; S113-I117 PolarHBondContact O-N 2.86Å
114L94.4Very high94.7Very high0 Ų018.5 Ų18.50%09%0.091CC..Hα-helixtrans-63.4-33.4178.7-70.2172.4000112.9V61 L65 I70 A74 V110 L111 M112 Q116 I117 V118V61-L114 HydrophobicContact CG1-CD2 4.44Å; L65-L114 HydrophobicContact CD1-CD2 3.98Å; L65-L114 HydrophobicContact CD2-CD2 4.37Å; I70-L114 HydrophobicContact CD1-CD2 3.9Å; I70-L114 HydrophobicContact CG1-CD2 3.64Å; A74-L114 VanDerWaalsContact CA-CD1 3.44Å; A74-L114 HydrophobicContact CB-CD1 3.64Å; V110-L114 HydrophobicContact CG1-CD1 3.9Å; V110-L114 HydrophobicContact CG1-CG 4.46Å; V110-L114 VanDerWaalsContact O-CG 3.26Å; V110-L114 WeakPolarHBondContact O-CG 3.46Å; V110-L114 PolarHBondContact O-N 3.48Å; L111-L114 PolarHBondContact O-N 3.44Å; M112-L114 VanDerWaalsContact C-N 3.34Å; M112-L114 PolarHBondContact O-N 2.84Å; L114-Q116 PolarHBondContact O-N 3.38Å; L114-Q116 VanDerWaalsContact O-N 3.11Å; L114-I117 PolarHBondContact O-N 3.39Å; L114-I117 VanDerWaalsContact O-N 3.13Å; L114-V118 HydrophobicContact CB-CG2 4.38Å; L114-V118 WeakPolarHBondContact O-CB 3.14Å; L114-V118 VanDerWaalsContact O-CG2 3.28Å; L114-V118 WeakPolarHBondContact O-CG2 3.21Å; L114-V118 PolarHBondContact O-N 2.8Å
115S92.5Very high94.6Very high4 Ų421.9 Ų21.93%0.02811%0.108CC..Hα-helixtrans-58.7-23.6174.981.60000113.6M16 L111 M112 S113 P119M16-S115 VanDerWaalsContact CE-CB 3.44Å; M16-S115 WeakPolarHBondContact CE-OG 3.13Å; L111-S115 PolarHBondContact O-N 2.98Å; M112-S115 WeakPolarHBondContact O-CB 3.23Å; M112-S115 PolarHBondContact O-N 3.39Å; M112-S115 PolarHBondContact O-OG 3.44Å; S113-S115 VanDerWaalsContact C-N 3.28Å; S113-S115 PolarHBondContact O-N 3.39Å; S115-P119 WeakPolarHBondContact O-CD 3.33Å; S115-P119 WeakPolarHBondContact O-CG 3.05Å
116Q92.4Very high94.6Very high19 Ų1924.6 Ų24.69%0.08913%0.126CC..Hα-helixtrans-94.4-28.3178.2-57.7-53.6-52.400112.6S113 L114 S367 Q371 M383 Y386S113-Q116 PolarHBondContact O-N 3.3Å; L114-Q116 PolarHBondContact O-N 3.38Å; L114-Q116 VanDerWaalsContact O-N 3.11Å; Q116-S367 PolarHBondContact OE1-OG 3.24Å; Q116-Q371 PolarHBondContact O-NE2 3.44Å; Q116-M383 HydrophobicContact CB-CE 3.59Å; Q116-Y386 HydrophobicContact CG-CD1 4.27Å; Q116-Y386 HydrophobicContact CG-CE1 4.42Å
117I94.8Very high94.5Very high0 Ų023.6 Ų23.60%012%0.124CC..Hα-helixtrans-86-47.5-176.3-65169.3000111.6V61 L65 I70 S113 L114 K120 L121 K380 M383V61-I117 HydrophobicContact CG1-CD1 4.37Å; L65-I117 HydrophobicContact CD1-CD1 3.48Å; L65-I117 VanDerWaalsContact CD1-CD1 3.48Å; L65-I117 HydrophobicContact CD1-CG2 4.36Å; I70-I117 HydrophobicContact CD1-CG2 4.27Å; S113-I117 WeakPolarHBondContact O-CG1 3.48Å; S113-I117 PolarHBondContact O-N 2.86Å; L114-I117 PolarHBondContact O-N 3.39Å; L114-I117 VanDerWaalsContact O-N 3.13Å; I117-K120 WeakPolarHBondContact O-CB 3.32Å; I117-K120 PolarHBondContact O-N 2.82Å; I117-K120 VanDerWaalsContact O-N 3.1Å; I117-L121 HydrophobicContact CG2-CD1 3.92Å; I117-L121 HydrophobicContact CG2-CG 4.39Å; I117-L121 PolarHBondContact O-N 3.4Å; I117-K380 HydrophobicContact CG2-CG 4.41Å; I117-M383 HydrophobicContact CD1-CB 4.24Å; I117-M383 HydrophobicContact CG1-CB 3.51Å; I117-M383 HydrophobicContact CG1-CG 4.27Å
118V95.4Very high94.4Very high0 Ų024.1 Ų24.10%013%0.126CC..Hα-helixtrans-59.6-39.1-173.9175.60000112.7T8 L12 I70 L114 K120 L121 A122 F181 F183T8-V118 HydrophobicContact CG2-CG1 3.95Å; L12-V118 HydrophobicContact CD1-CB 4.45Å; L12-V118 HydrophobicContact CD1-CG1 4.02Å; L12-V118 HydrophobicContact CD2-CB 3.84Å; L12-V118 HydrophobicContact CD2-CG1 3.96Å; L12-V118 HydrophobicContact CD2-CG2 4.33Å; L12-V118 HydrophobicContact CG-CG1 4.27Å; I70-V118 HydrophobicContact CD1-CG2 3.65Å; L114-V118 HydrophobicContact CB-CG2 4.38Å; L114-V118 WeakPolarHBondContact O-CB 3.14Å; L114-V118 VanDerWaalsContact O-CG2 3.28Å; L114-V118 WeakPolarHBondContact O-CG2 3.21Å; L114-V118 PolarHBondContact O-N 2.8Å; V118-K120 PolarHBondContact O-N 2.9Å; V118-L121 PolarHBondContact O-N 3.28Å; V118-L121 VanDerWaalsContact O-N 3.12Å; V118-A122 HydrophobicContact CG1-CB 4.29Å; V118-A122 VanDerWaalsContact O-CB 3.26Å; V118-A122 WeakPolarHBondContact O-CB 3.43Å; V118-A122 PolarHBondContact O-N 3.48Å; V118-F181 HydrophobicContact CB-CZ 4.44Å; V118-F181 HydrophobicContact CG1-CE1 4.04Å; V118-F181 HydrophobicContact CG1-CE2 4.48Å; V118-F181 HydrophobicContact CG1-CZ 3.94Å; V118-F181 HydrophobicContact CG2-CD2 4.27Å; V118-F181 HydrophobicContact CG2-CE2 3.63Å; V118-F181 HydrophobicContact CG2-CZ 3.83Å; V118-F183 HydrophobicContact CG1-CE2 4.38Å; V118-F183 HydrophobicContact CG1-CZ 3.94Å
119P95.1Very high94.5Very high0 Ų024.4 Ų24.40%013%0.127CC..Hα-helixtrans-57.3-34.1176.5-27.336.1000114.2L12 S115 F123 R128 M132L12-P119 HydrophobicContact CD1-CG 4.21Å; S115-P119 WeakPolarHBondContact O-CD 3.33Å; S115-P119 WeakPolarHBondContact O-CG 3.05Å; P119-F123 PolarHBondContact O-N 3.49Å; P119-F123 VanDerWaalsContact O-N 3.17Å; P119-R128 HydrophobicContact CB-CG 3.98Å; P119-R128 PolarHBondContact O-NE 3.02Å; P119-M132 HydrophobicContact CB-CG 3.79Å; P119-M132 HydrophobicContact CB-SD 4.21Å; P119-M132 HydrophobicContact CG-CG 4.1Å
120K94.5Very high94.6Very high48 Ų4827.5 Ų27.521%0.20914%0.14CC..Hα-helixtrans-65.2-46.2174.617260-179-138.80111.8I117 V118 R128 Q371 E372 M379I117-K120 WeakPolarHBondContact O-CB 3.32Å; I117-K120 PolarHBondContact O-N 2.82Å; I117-K120 VanDerWaalsContact O-N 3.1Å; V118-K120 PolarHBondContact O-N 2.9Å; K120-R128 VanDerWaalsContact CD-CZ 3.46Å; K120-R128 PolarHBondContact O-NH2 3.42Å; K120-Q371 HydrophobicContact CB-CB 4.32Å; K120-Q371 HydrophobicContact CB-CG 3.92Å; K120-Q371 HydrophobicContact CD-CB 4.11Å; K120-Q371 HydrophobicContact CG-CB 4.25Å; K120-Q371 HydrophobicContact CG-CG 4.34Å; K120-Q371 PolarHBondContact NZ-O 3.32Å; K120-E372 IonicContact NZ-OE1 2.77Å; K120-E372 PolarHBondContact NZ-OE1 2.9Å; K120-E372 IonicContact NZ-OE2 2.7Å; K120-E372 PolarHBondContact NZ-OE2 3.17Å; K120-M379 HydrophobicContact CG-CE 3.82Å; K120-M379 HydrophobicContact CG-SD 4.15Å
121L92.9Very high94.6Very high19 Ų1927 Ų2710%0.09914%0.137CC..Hα-helixtrans-74.7-28.1-176.3-58.4178.3000113.1I70 I117 V118 F183 M379I70-L121 HydrophobicContact CD1-CD1 3.68Å; I117-L121 HydrophobicContact CG2-CD1 3.92Å; I117-L121 HydrophobicContact CG2-CG 4.39Å; I117-L121 PolarHBondContact O-N 3.4Å; V118-L121 PolarHBondContact O-N 3.28Å; V118-L121 VanDerWaalsContact O-N 3.12Å; L121-F183 HydrophobicContact CB-CB 4.37Å; L121-F183 HydrophobicContact CB-CD1 4.18Å; L121-F183 HydrophobicContact CB-CD2 4.04Å; L121-F183 HydrophobicContact CB-CE2 4.42Å; L121-F183 HydrophobicContact CB-CG 3.92Å; L121-F183 HydrophobicContact CD1-CD2 4.1Å; L121-M379 HydrophobicContact CD2-CE 3.88Å
122A94.3Very high94.6Very high27 Ų2727.7 Ų27.722%0.22314%0.141CC..Hα-helixtrans-98.2-24.1-172.200000114.1T8 V118 F183T8-A122 HydrophobicContact CG2-CB 3.99Å; V118-A122 HydrophobicContact CG1-CB 4.29Å; V118-A122 VanDerWaalsContact O-CB 3.26Å; V118-A122 WeakPolarHBondContact O-CB 3.43Å; V118-A122 PolarHBondContact O-N 3.48Å; A122-F183 HydrophobicContact CB-CD1 4.48Å; A122-F183 HydrophobicContact CB-CE1 3.62Å; A122-F183 HydrophobicContact CB-CZ 4.09Å
123F94.8Very high94.7Very high10 Ų1027 Ų274%0.04414%0.137CC..  trans-141.2140.3-169.1-51-68.3000112.8M1 T8 V9 L12 P119 L127 R128 I131M1-F123 HydrophobicContact CE-CE1 4.11Å; T8-F123 HydrophobicContact CG2-CE2 4.16Å; T8-F123 HydrophobicContact CG2-CZ 4Å; V9-F123 HydrophobicContact CG2-CE1 4.38Å; V9-F123 HydrophobicContact CG2-CE2 4.12Å; V9-F123 HydrophobicContact CG2-CZ 3.64Å; L12-F123 HydrophobicContact CD1-CE2 4.47Å; P119-F123 PolarHBondContact O-N 3.49Å; P119-F123 VanDerWaalsContact O-N 3.17Å; F123-L127 HydrophobicContact CD1-CD2 3.85Å; F123-L127 HydrophobicContact CD1-CG 4.32Å; F123-R128 HydrophobicContact CB-CB 4.13Å; F123-R128 VanDerWaalsContact O-CZ 3.27Å; F123-R128 PolarHBondContact O-NE 2.93Å; F123-R128 PolarHBondContact O-NH2 3.34Å; F123-I131 HydrophobicContact CD1-CG1 4.36Å; F123-I131 HydrophobicContact CD2-CB 4.15Å; F123-I131 HydrophobicContact CD2-CG1 3.82Å; F123-I131 HydrophobicContact CD2-CG2 4.04Å; F123-I131 HydrophobicContact CE1-CG1 4.47Å; F123-I131 HydrophobicContact CE2-CB 4.32Å; F123-I131 HydrophobicContact CE2-CG1 3.95Å; F123-I131 HydrophobicContact CE2-CG2 3.8Å; F123-I131 HydrophobicContact CG-CG1 4.04Å; F123-I131 HydrophobicContact CZ-CG1 4.28Å
124E94.6Very high94.7Very high161 Ų16129 Ų2975%0.75215%0.148SC*.  trans-86.6159.3169.5-64.9-179172.200111.6L127 R128E124-L127 PolarHBondContact O-N 3.26Å; E124-R128 PolarHBondContact O-N 3.39Å
125I95.6Very high94.7Very high71 Ų7129.2 Ų29.236%0.36415%0.149SC..THydrogen-bonded Turntrans-71.8134.2169.6-64.6172.8000107.7R128 Y129 V368 E372I125-R128 HydrophobicContact CG1-CB 4.38Å; I125-Y129 HydrophobicContact CD1-CE1 3.84Å; I125-Y129 HydrophobicContact CG1-CD1 4.41Å; I125-Y129 HydrophobicContact CG1-CE1 3.81Å; I125-Y129 HydrophobicContact CG2-CD2 4.34Å; I125-Y129 HydrophobicContact CG2-CE1 3.99Å; I125-Y129 HydrophobicContact CG2-CE2 3.72Å; I125-V368 HydrophobicContact CD1-CG1 3.87Å; I125-E372 HydrophobicContact CD1-CG 4.44Å
126P95Very high94.4Very high57 Ų5729.4 Ų29.437%0.3715%0.152SC..THydrogen-bonded Turncis-96-3.113.337.1-37.2000115.4R128 Y129 H312P126-R128 PolarHBondContact O-N 3.23Å; P126-Y129 HydrophobicContact CB-CD2 4.38Å; P126-Y129 WeakPolarHBondContact O-CB 3.29Å; P126-Y129 PolarHBondContact O-N 3.43Å; P126-H312 HydrophobicContact CB-CB 3.54Å; P126-H312 HydrophobicContact CG-CB 4.43Å
127L95.2Very high94.3Very high53 Ų5328.7 Ų28.728%0.27715%0.148SC..Hα-helixtrans-60.7-36.6-179.2-178.960.2000111.2M1 F123 E124 Y129 K130 I131M1-L127 HydrophobicContact CE-CD2 4.34Å; M1-L127 HydrophobicContact CG-CD1 4.29Å; M1-L127 HydrophobicContact CG-CD2 4.06Å; M1-L127 HydrophobicContact SD-CD1 3.95Å; M1-L127 HydrophobicContact SD-CD2 4.4Å; F123-L127 HydrophobicContact CD1-CD2 3.85Å; F123-L127 HydrophobicContact CD1-CG 4.32Å; E124-L127 PolarHBondContact O-N 3.26Å; L127-Y129 VanDerWaalsContact C-N 3.28Å; L127-Y129 PolarHBondContact O-N 2.84Å; L127-K130 HydrophobicContact CD1-CD 4.34Å; L127-K130 WeakPolarHBondContact O-CB 3.48Å; L127-K130 PolarHBondContact O-N 3.28Å; L127-I131 HydrophobicContact CD1-CD1 4.18Å; L127-I131 HydrophobicContact CG-CD1 4.49Å; L127-I131 HydrophobicContact CG-CG1 4.32Å; L127-I131 WeakPolarHBondContact O-CG1 3.27Å; L127-I131 PolarHBondContact O-N 3.11Å; L127-I131 VanDerWaalsContact O-N 3.08Å
128R96.5Very high94Very high11 Ų1128.9 Ų28.94%0.04215%0.15CC..Hα-helixtrans-54.4-41.3176.4-166.9-174.7-56.81579.5113.1P119 K120 F123 E124 I125 P126 K130 I131 M132 Q371 E372P119-R128 HydrophobicContact CB-CG 3.98Å; P119-R128 PolarHBondContact O-NE 3.02Å; K120-R128 VanDerWaalsContact CD-CZ 3.46Å; K120-R128 PolarHBondContact O-NH2 3.42Å; F123-R128 HydrophobicContact CB-CB 4.13Å; F123-R128 VanDerWaalsContact O-CZ 3.27Å; F123-R128 PolarHBondContact O-NE 2.93Å; F123-R128 PolarHBondContact O-NH2 3.34Å; E124-R128 PolarHBondContact O-N 3.39Å; I125-R128 HydrophobicContact CG1-CB 4.38Å; P126-R128 PolarHBondContact O-N 3.23Å; R128-K130 VanDerWaalsContact C-N 3.29Å; R128-K130 PolarHBondContact O-N 3.41Å; R128-I131 PolarHBondContact O-N 2.91Å; R128-M132 HydrophobicContact CG-CG 4.24Å; R128-M132 HydrophobicContact CG-SD 3.71Å; R128-M132 WeakPolarHBondContact O-CG 3.48Å; R128-M132 PolarHBondContact O-N 2.9Å; R128-Q371 VanDerWaalsContact CD-OE1 3.22Å; R128-E372 IonicContact CZ-OE1 3.58Å; R128-E372 IonicContact NH1-OE1 3.54Å; R128-E372 PolarHBondContact NH1-OE1 3.36Å; R128-E372 IonicContact NH2-OE1 2.67Å
129Y96.9Very high93.2Very high6 Ų630.8 Ų30.82%0.02416%0.157CC..Hα-helixtrans-58.9-43.7177.5-60.2-18.3000111.5I125 P126 L127 I131 M132 G133 N308 L311 H312 E315 T364 V368I125-Y129 HydrophobicContact CD1-CE1 3.84Å; I125-Y129 HydrophobicContact CG1-CD1 4.41Å; I125-Y129 HydrophobicContact CG1-CE1 3.81Å; I125-Y129 HydrophobicContact CG2-CD2 4.34Å; I125-Y129 HydrophobicContact CG2-CE1 3.99Å; I125-Y129 HydrophobicContact CG2-CE2 3.72Å; P126-Y129 HydrophobicContact CB-CD2 4.38Å; P126-Y129 WeakPolarHBondContact O-CB 3.29Å; P126-Y129 PolarHBondContact O-N 3.43Å; L127-Y129 VanDerWaalsContact C-N 3.28Å; L127-Y129 PolarHBondContact O-N 2.84Å; Y129-I131 PolarHBondContact O-N 3.13Å; Y129-M132 PolarHBondContact O-N 3.38Å; Y129-G133 PolarHBondContact O-N 2.94Å; Y129-N308 PolarHBondContact O-OD1 2.94Å; Y129-L311 HydrophobicContact CD1-CD2 4.21Å; Y129-L311 HydrophobicContact CD2-CB 3.86Å; Y129-L311 HydrophobicContact CD2-CD2 3.89Å; Y129-L311 HydrophobicContact CD2-CG 3.8Å; Y129-L311 HydrophobicContact CE2-CB 4.46Å; Y129-L311 HydrophobicContact CE2-CD2 4.2Å; Y129-L311 HydrophobicContact CE2-CG 3.99Å; Y129-L311 HydrophobicContact CG-CB 4.36Å; Y129-L311 HydrophobicContact CG-CD2 3.87Å; Y129-L311 HydrophobicContact CG-CG 4.28Å; Y129-H312 HydrophobicContact CD2-CB 4.33Å; Y129-H312 HydrophobicContact CE2-CB 4.41Å; Y129-E315 VanDerWaalsContact CE2-OE2 3.29Å; Y129-E315 WeakPolarHBondContact CE2-OE2 3.42Å; Y129-E315 PolarHBondContact OH-OE2 3.02Å; Y129-T364 HydrophobicContact CD1-CG2 4Å; Y129-T364 HydrophobicContact CG-CG2 4.44Å; Y129-V368 HydrophobicContact CD1-CG2 4.03Å; Y129-V368 HydrophobicContact CE1-CB 4.38Å; Y129-V368 HydrophobicContact CE1-CG1 4.04Å; Y129-V368 HydrophobicContact CE1-CG2 3.78Å
130K96Very high92.4Very high66 Ų6630.9 Ų30.929%0.28716%0.158SC..Hα-helixtrans-61.9-45.6177.1-59.2-179.4179.9179.40111L127 R128 G133 I134 F309L127-K130 HydrophobicContact CD1-CD 4.34Å; L127-K130 WeakPolarHBondContact O-CB 3.48Å; L127-K130 PolarHBondContact O-N 3.28Å; R128-K130 VanDerWaalsContact C-N 3.29Å; R128-K130 PolarHBondContact O-N 3.41Å; K130-G133 PolarHBondContact O-N 3.34Å; K130-I134 VanDerWaalsContact O-CG1 3.27Å; K130-I134 WeakPolarHBondContact O-CG1 3.3Å; K130-I134 PolarHBondContact O-N 2.92Å; K130-F309 HydrophobicContact CB-CD2 4.11Å; K130-F309 HydrophobicContact CB-CE2 3.89Å; K130-F309 HydrophobicContact CB-CZ 4.15Å; K130-F309 HydrophobicContact CD-CD1 4.14Å; K130-F309 HydrophobicContact CD-CE1 4.22Å; K130-F309 HydrophobicContact CD-CG 4.44Å; K130-F309 HydrophobicContact CG-CD1 4.29Å; K130-F309 HydrophobicContact CG-CD2 4.1Å; K130-F309 HydrophobicContact CG-CE1 4.48Å; K130-F309 HydrophobicContact CG-CE2 4.29Å; K130-F309 HydrophobicContact CG-CG 4.1Å; K130-F309 HydrophobicContact CG-CZ 4.49Å
131I95.5Very high91.9Very high2 Ų231.2 Ų31.21%0.0116%0.161CC..Hα-helixtrans-65.9-44.3-178.6-57.6-36.9000111.2M1 V9 L12 F123 L127 R128 Y129 G133 I134 V135M1-I131 HydrophobicContact CE-CD1 4.05Å; M1-I131 HydrophobicContact SD-CD1 4.47Å; V9-I131 HydrophobicContact CG1-CD1 4.41Å; V9-I131 HydrophobicContact CG2-CB 4.5Å; V9-I131 HydrophobicContact CG2-CD1 3.45Å; V9-I131 VanDerWaalsContact CG2-CD1 3.45Å; V9-I131 HydrophobicContact CG2-CG1 3.89Å; V9-I131 HydrophobicContact CG2-CG2 3.86Å; L12-I131 HydrophobicContact CD1-CG2 4.22Å; F123-I131 HydrophobicContact CD1-CG1 4.36Å; F123-I131 HydrophobicContact CD2-CB 4.15Å; F123-I131 HydrophobicContact CD2-CG1 3.82Å; F123-I131 HydrophobicContact CD2-CG2 4.04Å; F123-I131 HydrophobicContact CE1-CG1 4.47Å; F123-I131 HydrophobicContact CE2-CB 4.32Å; F123-I131 HydrophobicContact CE2-CG1 3.95Å; F123-I131 HydrophobicContact CE2-CG2 3.8Å; F123-I131 HydrophobicContact CG-CG1 4.04Å; F123-I131 HydrophobicContact CZ-CG1 4.28Å; L127-I131 HydrophobicContact CD1-CD1 4.18Å; L127-I131 HydrophobicContact CG-CD1 4.49Å; L127-I131 HydrophobicContact CG-CG1 4.32Å; L127-I131 WeakPolarHBondContact O-CG1 3.27Å; L127-I131 PolarHBondContact O-N 3.11Å; L127-I131 VanDerWaalsContact O-N 3.08Å; R128-I131 PolarHBondContact O-N 2.91Å; Y129-I131 PolarHBondContact O-N 3.13Å; I131-G133 VanDerWaalsContact C-N 3.31Å; I131-G133 PolarHBondContact O-N 3.18Å; I131-I134 HydrophobicContact CD1-CD1 4.23Å; I131-I134 PolarHBondContact O-N 3.16Å; I131-V135 HydrophobicContact CG2-CG2 4.31Å; I131-V135 WeakPolarHBondContact O-CG2 3.45Å; I131-V135 PolarHBondContact O-N 3.39Å
132M94.7Very high91.7Very high13 Ų1330.4 Ų30.46%0.06416%0.157CC..Hα-helixtrans-65.6-35.9177.1-68173.871.900111.9P119 R128 Y129 G136 T364 S367 V368P119-M132 HydrophobicContact CB-CG 3.79Å; P119-M132 HydrophobicContact CB-SD 4.21Å; P119-M132 HydrophobicContact CG-CG 4.1Å; R128-M132 HydrophobicContact CG-CG 4.24Å; R128-M132 HydrophobicContact CG-SD 3.71Å; R128-M132 WeakPolarHBondContact O-CG 3.48Å; R128-M132 PolarHBondContact O-N 2.9Å; Y129-M132 PolarHBondContact O-N 3.38Å; M132-G136 PolarHBondContact O-N 3.25Å; M132-T364 HydrophobicContact CB-CG2 4.09Å; M132-T364 HydrophobicContact SD-CG2 4.39Å; M132-S367 WeakPolarHBondContact CE-OG 3.46Å; M132-V368 HydrophobicContact CE-CG2 4.16Å; M132-V368 HydrophobicContact SD-CG2 3.79Å
133G94.2Very high91Very high0 Ų030.2 Ų30.20%015%0.154CC..Hα-helixtrans-61-46.6170.100000113Y129 K130 I131 G136 S137Y129-G133 PolarHBondContact O-N 2.94Å; K130-G133 PolarHBondContact O-N 3.34Å; I131-G133 VanDerWaalsContact C-N 3.31Å; I131-G133 PolarHBondContact O-N 3.18Å; G133-G136 PolarHBondContact O-N 3.31Å; G133-S137 VanDerWaalsContact O-CB 3.29Å; G133-S137 WeakPolarHBondContact O-CB 3.42Å; G133-S137 PolarHBondContact O-N 2.96Å; G133-S137 PolarHBondContact O-OG 2.73Å
134I94.8Very high90.7Very high43 Ų4331 Ų3122%0.22116%0.159CC..Hα-helixtrans-60-53.1176.3-68.4162.8000110V9 I13 K130 I131 G136 S137 V138 F309V9-I134 HydrophobicContact CG1-CG2 4.44Å; I13-I134 HydrophobicContact CD1-CG2 3.62Å; I13-I134 HydrophobicContact CG1-CG2 3.84Å; K130-I134 VanDerWaalsContact O-CG1 3.27Å; K130-I134 WeakPolarHBondContact O-CG1 3.3Å; K130-I134 PolarHBondContact O-N 2.92Å; I131-I134 HydrophobicContact CD1-CD1 4.23Å; I131-I134 PolarHBondContact O-N 3.16Å; I134-G136 PolarHBondContact O-N 2.76Å; I134-S137 PolarHBondContact O-N 3.14Å; I134-S137 PolarHBondContact O-OG 2.85Å; I134-V138 PolarHBondContact O-N 3.26Å; I134-F309 HydrophobicContact CD1-CE2 4.18Å; I134-F309 HydrophobicContact CD1-CZ 4.08Å; I134-F309 HydrophobicContact CG1-CE2 3.97Å; I134-F309 HydrophobicContact CG1-CZ 4.29Å
135V93.2Very high90.4Very high4 Ų426.2 Ų26.22%0.02414%0.137CC..Hα-helixtrans-61.7-43.2-179.1174.50000111.1L12 M16 I131 S137 V138L12-V135 HydrophobicContact CB-CG2 3.71Å; L12-V135 HydrophobicContact CD1-CG2 4.44Å; M16-V135 HydrophobicContact CB-CG1 3.89Å; M16-V135 HydrophobicContact CE-CG1 3.69Å; M16-V135 HydrophobicContact CG-CG1 4.02Å; M16-V135 WeakPolarHBondContact CG-O 3.07Å; I131-V135 HydrophobicContact CG2-CG2 4.31Å; I131-V135 WeakPolarHBondContact O-CG2 3.45Å; I131-V135 PolarHBondContact O-N 3.39Å; V135-S137 PolarHBondContact O-N 2.91Å; V135-V138 WeakPolarHBondContact O-CB 3.42Å; V135-V138 WeakPolarHBondContact O-CG2 3.09Å; V135-V138 PolarHBondContact O-N 3.43Å
136G87Confident90.1Very high8 Ų822.8 Ų22.88%0.08212%0.12CC..Hα-helixtrans-63.2-39.5178.200000113.2M132 G133 I134 V138 W139M132-G136 PolarHBondContact O-N 3.25Å; G133-G136 PolarHBondContact O-N 3.31Å; I134-G136 PolarHBondContact O-N 2.76Å; G136-V138 PolarHBondContact O-N 3.5Å; G136-W139 PolarHBondContact O-N 3.34Å
137S89.2Confident89.7Confident3 Ų321.1 Ų21.12%0.02111%0.109CC..Hα-helixtrans-68.2-15.7-179.473.80000115.3G133 I134 V135 W139 G140 I141 S301 I305G133-S137 VanDerWaalsContact O-CB 3.29Å; G133-S137 WeakPolarHBondContact O-CB 3.42Å; G133-S137 PolarHBondContact O-N 2.96Å; G133-S137 PolarHBondContact O-OG 2.73Å; I134-S137 PolarHBondContact O-N 3.14Å; I134-S137 PolarHBondContact O-OG 2.85Å; V135-S137 PolarHBondContact O-N 2.91Å; S137-W139 PolarHBondContact O-N 2.9Å; S137-W139 VanDerWaalsContact O-N 3.1Å; S137-G140 PolarHBondContact O-N 3.34Å; S137-I141 PolarHBondContact O-N 3.49Å; S137-S301 PolarHBondContact O-OG 2.94Å; S137-I305 VanDerWaalsContact CB-CD1 3.4Å; S137-I305 WeakPolarHBondContact OG-CD1 3.28Å; S137-I305 WeakPolarHBondContact OG-CG1 3.42Å
138V89.5Confident89.4Confident5 Ų523.6 Ų23.63%0.0312%0.122CC..Hα-helixtrans-54.9-30.3175.8177.20000110.9I13 M16 F17 I134 V135 G136 G140 I141 S142I13-V138 HydrophobicContact CG2-CG2 4.11Å; M16-V138 HydrophobicContact CB-CB 4.43Å; M16-V138 HydrophobicContact CB-CG1 4.42Å; M16-V138 HydrophobicContact CG-CB 4.01Å; M16-V138 HydrophobicContact CG-CG1 4.24Å; F17-V138 VanDerWaalsContact CA-CG1 3.43Å; F17-V138 HydrophobicContact CB-CG1 3.72Å; F17-V138 HydrophobicContact CD2-CG1 4.06Å; F17-V138 HydrophobicContact CG-CG1 4.41Å; I134-V138 PolarHBondContact O-N 3.26Å; V135-V138 WeakPolarHBondContact O-CB 3.42Å; V135-V138 WeakPolarHBondContact O-CG2 3.09Å; V135-V138 PolarHBondContact O-N 3.43Å; G136-V138 PolarHBondContact O-N 3.5Å; V138-G140 PolarHBondContact O-N 2.94Å; V138-I141 PolarHBondContact O-N 3.33Å; V138-S142 WeakPolarHBondContact O-CB 3.48Å; V138-S142 PolarHBondContact O-N 2.96Å; V138-S142 PolarHBondContact O-OG 3.36Å; V138-S142 VanDerWaalsContact O-OG 3.04Å
139W78Confident89Confident40 Ų4026 Ų2615%0.15214%0.135CC..Hα-helixtrans-57-49.8178-80.381.8000113.9M16 A20 M112 G136 S137 S142 S143M16-W139 PolarHBondContact SD-NE1 3.28Å; A20-W139 HydrophobicContact CB-CD2 3.87Å; A20-W139 HydrophobicContact CB-CE3 4.15Å; A20-W139 HydrophobicContact CB-CG 4.18Å; A20-W139 HydrophobicContact CB-CZ2 4.36Å; M112-W139 HydrophobicContact CE-CZ2 4.06Å; G136-W139 PolarHBondContact O-N 3.34Å; S137-W139 PolarHBondContact O-N 2.9Å; S137-W139 VanDerWaalsContact O-N 3.1Å; W139-S142 WeakPolarHBondContact O-CB 3.48Å; W139-S142 PolarHBondContact O-N 3.42Å; W139-S143 PolarHBondContact O-N 3.09Å; W139-S143 VanDerWaalsContact O-N 3.15Å; W139-S143 PolarHBondContact O-OG 3.16Å
140G77.4Confident88.7Confident2 Ų225.7 Ų25.72%0.02113%0.134CC..Hα-helixtrans-84.6-18.1179.200000113.8S137 V138 S143 S301S137-G140 PolarHBondContact O-N 3.34Å; V138-G140 PolarHBondContact O-N 2.94Å; G140-S143 WeakPolarHBondContact O-CB 3.39Å; G140-S143 PolarHBondContact O-N 2.97Å; G140-S301 WeakPolarHBondContact CA-OG 2.9Å; G140-S301 PolarHBondContact N-OG 2.78Å
141I85.9Confident88.3Confident55 Ų5524.1 Ų24.128%0.28214%0.137SC..Hα-helixtrans-63.8-45.3163.7-65168.6000109.5S137 V138 S143 I144 I145 F298S137-I141 PolarHBondContact O-N 3.49Å; V138-I141 PolarHBondContact O-N 3.33Å; I141-S143 PolarHBondContact O-N 3.35Å; I141-I144 PolarHBondContact O-N 2.99Å; I141-I145 HydrophobicContact CG2-CD1 3.54Å; I141-I145 HydrophobicContact CG2-CG1 4.12Å; I141-I145 PolarHBondContact O-N 2.92Å; I141-F298 HydrophobicContact CG1-CE2 4.19Å
142S86.8Confident88Confident1 Ų125.3 Ų25.31%0.00715%0.149CC..Hα-helixtrans-61.4-29.3174.7-67.80000112.4F17 S24 V138 W139 I144 G146F17-S142 WeakPolarHBondContact CD2-OG 3.49Å; S24-S142 PolarHBondContact OG-O 3.05Å; V138-S142 WeakPolarHBondContact O-CB 3.48Å; V138-S142 PolarHBondContact O-N 2.96Å; V138-S142 PolarHBondContact O-OG 3.36Å; V138-S142 VanDerWaalsContact O-OG 3.04Å; W139-S142 WeakPolarHBondContact O-CB 3.48Å; W139-S142 PolarHBondContact O-N 3.42Å; S142-I144 PolarHBondContact O-N 3.36Å; S142-G146 VanDerWaalsContact O-CA 3.29Å; S142-G146 WeakPolarHBondContact O-CA 2.94Å; S142-G146 PolarHBondContact O-N 3.5Å
143S81.2Confident88Confident23 Ų2326 Ų2616%0.16115%0.153CC..Hα-helixtrans-66.2-19.6172.8-56.80000114.5W139 G140 I141 P147W139-S143 PolarHBondContact O-N 3.09Å; W139-S143 VanDerWaalsContact O-N 3.15Å; W139-S143 PolarHBondContact O-OG 3.16Å; G140-S143 WeakPolarHBondContact O-CB 3.39Å; G140-S143 PolarHBondContact O-N 2.97Å; I141-S143 PolarHBondContact O-N 3.35Å; S143-P147 WeakPolarHBondContact O-CD 3.41Å; S143-P147 WeakPolarHBondContact O-CG 3.35Å
144I87.2Confident87.9Confident27 Ų2728.4 Ų28.414%0.13817%0.166CC..Hα-helixtrans-92.2-51.9169.3-62.2161.9000110.4I141 S142 G146 P147 L148 L291 L295 F298I141-I144 PolarHBondContact O-N 2.99Å; S142-I144 PolarHBondContact O-N 3.36Å; I144-G146 VanDerWaalsContact C-N 3.28Å; I144-G146 PolarHBondContact O-N 2.99Å; I144-P147 WeakPolarHBondContact O-CD 3.22Å; I144-L148 WeakPolarHBondContact O-CB 3.49Å; I144-L148 PolarHBondContact O-N 3.4Å; I144-L291 HydrophobicContact CG2-CD1 3.98Å; I144-L295 HydrophobicContact CD1-CD2 4.25Å; I144-F298 HydrophobicContact CD1-CB 3.6Å; I144-F298 HydrophobicContact CD1-CD1 4.26Å; I144-F298 HydrophobicContact CD1-CD2 3.18Å; I144-F298 HydrophobicContact CD1-CE2 3.82Å; I144-F298 HydrophobicContact CD1-CG 3.42Å; I144-F298 VanDerWaalsContact CD1-CG 3.42Å; I144-F298 HydrophobicContact CG1-CB 4.31Å; I144-F298 HydrophobicContact CG1-CD2 4.37Å
145I89.1Confident87.7Confident60 Ų6033.2 Ų33.231%0.30819%0.187SC..Hα-helixtrans-65.2-38.3-173-62.4-178.4000110.1F17 I21 I141 L148 L149F17-I145 HydrophobicContact CE2-CB 4.3Å; F17-I145 HydrophobicContact CE2-CD1 4.08Å; F17-I145 HydrophobicContact CE2-CG2 4.08Å; F17-I145 HydrophobicContact CZ-CG2 3.88Å; I21-I145 HydrophobicContact CD1-CB 4.43Å; I21-I145 HydrophobicContact CD1-CG2 3.93Å; I141-I145 HydrophobicContact CG2-CD1 3.54Å; I141-I145 HydrophobicContact CG2-CG1 4.12Å; I141-I145 PolarHBondContact O-N 2.92Å; I145-L148 PolarHBondContact O-N 3.06Å; I145-L149 HydrophobicContact CG2-CB 4.38Å; I145-L149 HydrophobicContact CG2-CD1 4.36Å; I145-L149 WeakPolarHBondContact O-CB 3.29Å; I145-L149 PolarHBondContact O-N 3.27Å
146G88.6Confident87.7Confident0 Ų041.1 Ų41.10%022%0.221CC..Hα-helixtrans-55.8-59.2179.200000112.4I25 S142 I144 L148 L149 G150I25-G146 WeakPolarHBondContact CG1-O 3.4Å; S142-G146 VanDerWaalsContact O-CA 3.29Å; S142-G146 WeakPolarHBondContact O-CA 2.94Å; S142-G146 PolarHBondContact O-N 3.5Å; I144-G146 VanDerWaalsContact C-N 3.28Å; I144-G146 PolarHBondContact O-N 2.99Å; G146-L148 PolarHBondContact O-N 3.39Å; G146-L149 PolarHBondContact O-N 3.16Å; G146-G150 WeakPolarHBondContact O-CA 3.49Å; G146-G150 PolarHBondContact O-N 3.36Å
147P86.1Confident88Confident21 Ų2142.5 Ų42.514%0.13623%0.232CC..Hα-helixtrans-63.1-37.4178.1-27.335.8000115.1L28 S143 I144 G151 P290L28-P147 HydrophobicContact CD1-CB 4.13Å; S143-P147 WeakPolarHBondContact O-CD 3.41Å; S143-P147 WeakPolarHBondContact O-CG 3.35Å; I144-P147 WeakPolarHBondContact O-CD 3.22Å; P147-G151 WeakPolarHBondContact O-CA 3.34Å; P147-G151 PolarHBondContact O-N 3.3Å; P147-P290 HydrophobicContact CB-CB 3.75Å; P147-P290 HydrophobicContact CG-CB 4.45Å
148L88.9Confident88.3Confident105 Ų10546 Ų4655%0.5525%0.253SS..Hα-helixtrans-63.4-50.1177.4-179.865.4000111.4I144 I145 G146 G152I144-L148 WeakPolarHBondContact O-CB 3.49Å; I144-L148 PolarHBondContact O-N 3.4Å; I145-L148 PolarHBondContact O-N 3.06Å; G146-L148 PolarHBondContact O-N 3.39Å; L148-G152 PolarHBondContact O-N 2.77Å
149L89.7Confident88.6Confident62 Ų6245.9 Ų45.933%0.32525%0.252SS..Hα-helixtrans-73.6-40-177-169.2145000111I25 I145 G146 I153 I165I25-L149 HydrophobicContact CD1-CD2 3.69Å; I145-L149 HydrophobicContact CG2-CB 4.38Å; I145-L149 HydrophobicContact CG2-CD1 4.36Å; I145-L149 WeakPolarHBondContact O-CB 3.29Å; I145-L149 PolarHBondContact O-N 3.27Å; G146-L149 PolarHBondContact O-N 3.16Å; L149-I153 HydrophobicContact CD2-CD1 3.45Å; L149-I153 VanDerWaalsContact CD2-CD1 3.45Å; L149-I153 HydrophobicContact CD2-CG1 4.48Å; L149-I153 HydrophobicContact CG-CD1 4.2Å; L149-I153 WeakPolarHBondContact O-CB 3.36Å; L149-I153 WeakPolarHBondContact O-CG1 3.28Å; L149-I153 PolarHBondContact O-N 3.39Å; L149-I165 HydrophobicContact CD2-CD1 3.31Å; L149-I165 HydrophobicContact CD2-CG2 4.28Å
150G89.1Confident89.4Confident0 Ų045.7 Ų45.70%025%0.253CS..Hα-helixtrans-66.5-46.7176.500000112.8G146 I153 L154G146-G150 WeakPolarHBondContact O-CA 3.49Å; G146-G150 PolarHBondContact O-N 3.36Å; G150-I153 PolarHBondContact O-N 2.89Å; G150-L154 WeakPolarHBondContact O-CB 3.34Å; G150-L154 VanDerWaalsContact O-CG 3.3Å; G150-L154 WeakPolarHBondContact O-CG 3.43Å; G150-L154 PolarHBondContact O-N 3.33Å
151G87.6Confident90.3Very high33 Ų3352.2 Ų52.234%0.3428%0.277SS..Hα-helixtrans-61.5-47.1175.200000112.1P147 I153 L154 E155P147-G151 WeakPolarHBondContact O-CA 3.34Å; P147-G151 PolarHBondContact O-N 3.3Å; G151-I153 PolarHBondContact O-N 3.2Å; G151-L154 PolarHBondContact O-N 3.3Å; G151-E155 PolarHBondContact O-N 3.33Å
152G90.9Very high90.8Very high26 Ų2649.8 Ų49.827%0.26826%0.264SS..Hα-helixtrans-61.6-41.4176.900000113L148 E155 F156L148-G152 PolarHBondContact O-N 2.77Å; G152-E155 PolarHBondContact O-N 3.28Å; G152-F156 WeakPolarHBondContact O-CD2 3.32Å; G152-F156 PolarHBondContact O-N 2.85Å
153I93.1Very high91.2Very high29 Ų2949.8 Ų49.815%0.14926%0.264CS..Hα-helixtrans-65.5-43.5176.1-70.9168.7000111.2L149 G150 G151 E155 F156 A157 W161 L162 I165L149-I153 HydrophobicContact CD2-CD1 3.45Å; L149-I153 VanDerWaalsContact CD2-CD1 3.45Å; L149-I153 HydrophobicContact CD2-CG1 4.48Å; L149-I153 HydrophobicContact CG-CD1 4.2Å; L149-I153 WeakPolarHBondContact O-CB 3.36Å; L149-I153 WeakPolarHBondContact O-CG1 3.28Å; L149-I153 PolarHBondContact O-N 3.39Å; G150-I153 PolarHBondContact O-N 2.89Å; G151-I153 PolarHBondContact O-N 3.2Å; I153-E155 PolarHBondContact O-N 3.48Å; I153-F156 PolarHBondContact O-N 3.27Å; I153-A157 HydrophobicContact CG2-CB 4.21Å; I153-A157 CarbonylContact O-C 3.43Å; I153-A157 VanDerWaalsContact O-CA 3.32Å; I153-A157 WeakPolarHBondContact O-CA 3.47Å; I153-A157 WeakPolarHBondContact O-CB 3.33Å; I153-A157 PolarHBondContact O-N 2.99Å; I153-W161 HydrophobicContact CG2-CB 3.62Å; I153-L162 HydrophobicContact CB-CD2 3.6Å; I153-L162 HydrophobicContact CD1-CD2 3.89Å; I153-L162 HydrophobicContact CG1-CD2 4.35Å; I153-L162 HydrophobicContact CG2-CD2 3.54Å; I153-L162 HydrophobicContact CG2-CG 4.2Å; I153-I165 HydrophobicContact CD1-CD1 4.38Å; I153-I165 HydrophobicContact CD1-CG2 3.44Å; I153-I165 VanDerWaalsContact CD1-CG2 3.44Å
154L91.7Very high91.9Very high50 Ų5051.2 Ų51.226%0.26227%0.267SS..Hα-helixtrans-67.4-22179.9-71.1172.7000113.3L28 A29 G150 G151 W159 L162L28-L154 HydrophobicContact CB-CD1 4.23Å; A29-L154 HydrophobicContact CB-CD1 4.1Å; A29-L154 HydrophobicContact CB-CD2 4.23Å; G150-L154 WeakPolarHBondContact O-CB 3.34Å; G150-L154 VanDerWaalsContact O-CG 3.3Å; G150-L154 WeakPolarHBondContact O-CG 3.43Å; G150-L154 PolarHBondContact O-N 3.33Å; G151-L154 PolarHBondContact O-N 3.3Å; L154-W159 HydrophobicContact CD2-CB 3.85Å; L154-L162 HydrophobicContact CD1-CD1 4.33Å; L154-L162 HydrophobicContact CD2-CD1 3.99Å; L154-L162 HydrophobicContact CG-CD1 4.13Å
155E92.5Very high92.3Very high144 Ų14451.7 Ų51.767%0.67327%0.269SS*.Hα-helixtrans-73.3-38174.1-172.8176.8174.100112.2G151 G152 I153G151-E155 PolarHBondContact O-N 3.33Å; G152-E155 PolarHBondContact O-N 3.28Å; I153-E155 PolarHBondContact O-N 3.48Å
156F92.8Very high92.5Very high170 Ų17049 Ų4975%0.74626%0.255SS*.Hα-helixtrans-109.9-11.3-173.3-59.6-67.5000114.8G152 I153G152-F156 WeakPolarHBondContact O-CD2 3.32Å; G152-F156 PolarHBondContact O-N 2.85Å; I153-F156 PolarHBondContact O-N 3.27Å
157A93.9Very high92.8Very high37 Ų3750.7 Ų50.731%0.30626%0.264SS..SBendtrans-151.7170.5-172.100000112.4I153 W161I153-A157 HydrophobicContact CG2-CB 4.21Å; I153-A157 CarbonylContact O-C 3.43Å; I153-A157 VanDerWaalsContact O-CA 3.32Å; I153-A157 WeakPolarHBondContact O-CA 3.47Å; I153-A157 WeakPolarHBondContact O-CB 3.33Å; I153-A157 PolarHBondContact O-N 2.99Å; A157-W161 HydrophobicContact CB-CB 4.34Å; A157-W161 HydrophobicContact CB-CG 4.01Å
158T94.4Very high93.4Very high75 Ų7553.3 Ų53.346%0.4628%0.281SS..  trans-75.5159.617866.90000111.6H160 W161T158-H160 PolarHBondContact O-N 2.62Å; T158-H160 PolarHBondContact OG1-ND1 3.44Å; T158-H160 VanDerWaalsContact OG1-ND1 3.15Å; T158-W161 PolarHBondContact O-N 3.12Å; T158-W161 VanDerWaalsContact O-N 3.1Å
159W94.8Very high93.7Very high4 Ų450 Ų502%0.01526%0.263CS..THydrogen-bonded Turntrans-58.2-22.3178.264.6-96.3000113.5A29 I33 D36 L37 L97 L154 W161 L162 F163A29-W159 HydrophobicContact CB-CB 4.06Å; I33-W159 HydrophobicContact CD1-CD2 4.32Å; I33-W159 HydrophobicContact CD1-CE3 4.09Å; I33-W159 HydrophobicContact CG1-CB 4.19Å; I33-W159 HydrophobicContact CG1-CD2 3.59Å; I33-W159 HydrophobicContact CG1-CE3 3.82Å; I33-W159 HydrophobicContact CG1-CG 3.76Å; I33-W159 HydrophobicContact CG1-CZ3 4.49Å; D36-W159 PolarHBondContact OD2-NE1 3.43Å; L37-W159 HydrophobicContact CD1-CH2 3.84Å; L37-W159 HydrophobicContact CD1-CZ2 3.83Å; L37-W159 HydrophobicContact CD2-CZ2 3.99Å; L37-W159 HydrophobicContact CG-CH2 4.43Å; L37-W159 HydrophobicContact CG-CZ2 3.91Å; L97-W159 HydrophobicContact CD1-CZ3 4.32Å; L97-W159 HydrophobicContact CD2-CH2 4.41Å; L97-W159 HydrophobicContact CD2-CZ3 4.47Å; L154-W159 HydrophobicContact CD2-CB 3.85Å; W159-W161 PolarHBondContact O-N 3.22Å; W159-L162 HydrophobicContact CB-CD1 4.32Å; W159-L162 WeakPolarHBondContact O-CB 3.31Å; W159-L162 VanDerWaalsContact O-CG 3.3Å; W159-L162 WeakPolarHBondContact O-CG 3.4Å; W159-L162 PolarHBondContact O-N 3.22Å; W159-F163 HydrophobicContact CE3-CD2 4.08Å; W159-F163 AromaticContact CE3-CE2 3.67Å; W159-F163 HydrophobicContact CE3-CE2 3.67Å; W159-F163 AromaticContact CZ3-CD2 4Å; W159-F163 HydrophobicContact CZ3-CD2 4Å; W159-F163 AromaticContact CZ3-CE2 3.55Å; W159-F163 HydrophobicContact CZ3-CE2 3.55Å
160H96.8Very high94.1Very high35 Ų3547 Ų4716%0.16225%0.248CC..THydrogen-bonded Turntrans-55-36.4175.5-58.789000112.2D36 G89 S91 T158 L162 F163 Y164D36-H160 IonicContact OD2-CE1 3.74Å; G89-H160 WeakPolarHBondContact O-CB 3.34Å; G89-H160 PolarHBondContact O-CD2 3.39Å; S91-H160 PolarHBondContact O-NE2 3.23Å; T158-H160 PolarHBondContact O-N 2.62Å; T158-H160 PolarHBondContact OG1-ND1 3.44Å; T158-H160 VanDerWaalsContact OG1-ND1 3.15Å; H160-L162 PolarHBondContact O-N 3.45Å; H160-F163 PolarHBondContact O-N 2.89Å; H160-Y164 HydrophobicContact CB-CE2 4.28Å; H160-Y164 PolarHBondContact O-N 3.46Å
161W96.3Very high94.5Very high140 Ų14051.3 Ų51.353%0.5327%0.27SS..Hα-helixtrans-65.6-24179.5-73.691000113.4I153 A157 T158 W159 F163 Y164 I165I153-W161 HydrophobicContact CG2-CB 3.62Å; A157-W161 HydrophobicContact CB-CB 4.34Å; A157-W161 HydrophobicContact CB-CG 4.01Å; T158-W161 PolarHBondContact O-N 3.12Å; T158-W161 VanDerWaalsContact O-N 3.1Å; W159-W161 PolarHBondContact O-N 3.22Å; W161-F163 PolarHBondContact O-N 3.39Å; W161-F163 VanDerWaalsContact O-N 3.16Å; W161-Y164 HydrophobicContact CD2-CD2 4.13Å; W161-Y164 HydrophobicContact CE3-CD2 4.18Å; W161-Y164 HydrophobicContact CG-CD2 4.4Å; W161-Y164 PolarHBondContact O-N 3.08Å; W161-Y164 VanDerWaalsContact O-N 3.12Å; W161-I165 WeakPolarHBondContact O-CG2 3.44Å; W161-I165 PolarHBondContact O-N 3.37Å; W161-I165 VanDerWaalsContact O-N 3.09Å
162L94.8Very high95Very high3 Ų353.9 Ų53.92%0.01628%0.275CS..Hα-helixtrans-61.6-21173.3-57.8-178.6000113I25 A29 I153 L154 W159 H160 I165I25-L162 HydrophobicContact CG2-CB 3.64Å; I25-L162 HydrophobicContact CG2-CD1 3.8Å; I25-L162 HydrophobicContact CG2-CD2 3.63Å; I25-L162 HydrophobicContact CG2-CG 3.88Å; A29-L162 HydrophobicContact CB-CD1 3.48Å; A29-L162 VanDerWaalsContact CB-CD1 3.48Å; I153-L162 HydrophobicContact CB-CD2 3.6Å; I153-L162 HydrophobicContact CD1-CD2 3.89Å; I153-L162 HydrophobicContact CG1-CD2 4.35Å; I153-L162 HydrophobicContact CG2-CD2 3.54Å; I153-L162 HydrophobicContact CG2-CG 4.2Å; L154-L162 HydrophobicContact CD1-CD1 4.33Å; L154-L162 HydrophobicContact CD2-CD1 3.99Å; L154-L162 HydrophobicContact CG-CD1 4.13Å; W159-L162 HydrophobicContact CB-CD1 4.32Å; W159-L162 WeakPolarHBondContact O-CB 3.31Å; W159-L162 VanDerWaalsContact O-CG 3.3Å; W159-L162 WeakPolarHBondContact O-CG 3.4Å; W159-L162 PolarHBondContact O-N 3.22Å; H160-L162 PolarHBondContact O-N 3.45Å; L162-I165 WeakPolarHBondContact O-CD1 3.35Å; L162-I165 VanDerWaalsContact O-CG1 3.25Å; L162-I165 WeakPolarHBondContact O-CG1 3.46Å
163F96Very high95.3Very high1 Ų152.6 Ų52.60%0.00426%0.262CS..Hα-helixtrans-92.1-39.3171.9-64.7-81.9000112.1I26 S85 C88 L97 W159 H160 W161 I165 N166I26-F163 HydrophobicContact CD1-CD1 3.99Å; I26-F163 HydrophobicContact CD1-CE1 3.24Å; I26-F163 HydrophobicContact CD1-CE2 4.31Å; I26-F163 HydrophobicContact CD1-CZ 3.44Å; I26-F163 VanDerWaalsContact CD1-CZ 3.44Å; I26-F163 HydrophobicContact CG1-CE1 4.42Å; I26-F163 HydrophobicContact CG1-CZ 4.27Å; S85-F163 WeakPolarHBondContact O-CB 3.42Å; C88-F163 HydrophobicContact CB-CB 3.95Å; C88-F163 HydrophobicContact CB-CD1 3.22Å; C88-F163 HydrophobicContact CB-CD2 3.88Å; C88-F163 HydrophobicContact CB-CE1 3.48Å; C88-F163 VanDerWaalsContact CB-CE1 3.48Å; C88-F163 HydrophobicContact CB-CE2 4.13Å; C88-F163 HydrophobicContact CB-CG 3.41Å; C88-F163 VanDerWaalsContact CB-CG 3.41Å; C88-F163 HydrophobicContact CB-CZ 3.93Å; L97-F163 HydrophobicContact CD1-CE2 4.2Å; L97-F163 HydrophobicContact CD1-CZ 3.92Å; W159-F163 HydrophobicContact CE3-CD2 4.08Å; W159-F163 AromaticContact CE3-CE2 3.67Å; W159-F163 HydrophobicContact CE3-CE2 3.67Å; W159-F163 AromaticContact CZ3-CD2 4Å; W159-F163 HydrophobicContact CZ3-CD2 4Å; W159-F163 AromaticContact CZ3-CE2 3.55Å; W159-F163 HydrophobicContact CZ3-CE2 3.55Å; H160-F163 PolarHBondContact O-N 2.89Å; W161-F163 PolarHBondContact O-N 3.39Å; W161-F163 VanDerWaalsContact O-N 3.16Å; F163-I165 VanDerWaalsContact C-N 3.27Å; F163-I165 PolarHBondContact O-N 3.14Å; F163-N166 WeakPolarHBondContact O-CB 3.49Å; F163-N166 PolarHBondContact O-N 3.3Å; F163-N166 VanDerWaalsContact O-N 3.16Å
164Y96.4Very high95.6Very high54 Ų5452.5 Ų52.521%0.21226%0.261CS..Hα-helixtrans-64.1-27.8-178.9-66.1-42.9000114.1F86 G89 L90 H160 W161 N166 I167 P168F86-Y164 HydrophobicContact CD2-CD1 4.36Å; F86-Y164 AromaticContact CD2-CE1 3.88Å; F86-Y164 HydrophobicContact CD2-CE1 3.88Å; F86-Y164 HydrophobicContact CE2-CE1 4.28Å; G89-Y164 VanDerWaalsContact C-CZ 3.4Å; G89-Y164 PolarHBondContact O-OH 3.43Å; L90-Y164 VanDerWaalsContact CD2-OH 3.31Å; L90-Y164 WeakPolarHBondContact CD2-OH 3.25Å; L90-Y164 PolarHBondContact N-OH 3.35Å; H160-Y164 HydrophobicContact CB-CE2 4.28Å; H160-Y164 PolarHBondContact O-N 3.46Å; W161-Y164 HydrophobicContact CD2-CD2 4.13Å; W161-Y164 HydrophobicContact CE3-CD2 4.18Å; W161-Y164 HydrophobicContact CG-CD2 4.4Å; W161-Y164 PolarHBondContact O-N 3.08Å; W161-Y164 VanDerWaalsContact O-N 3.12Å; Y164-N166 PolarHBondContact O-N 3.28Å; Y164-N166 VanDerWaalsContact O-N 3.09Å; Y164-I167 WeakPolarHBondContact O-CB 3.21Å; Y164-I167 PolarHBondContact O-N 3.29Å; Y164-P168 WeakPolarHBondContact O-CD 3.4Å
165I94.3Very high95.9Very high36 Ų3653.5 Ų53.519%0.18527%0.266CS..THydrogen-bonded Turntrans-55.8-26.3174.159.2175.9000113.8I25 L149 I153 W161 L162 F163 I167 P168 I169I25-I165 HydrophobicContact CD1-CD1 3.51Å; L149-I165 HydrophobicContact CD2-CD1 3.31Å; L149-I165 HydrophobicContact CD2-CG2 4.28Å; I153-I165 HydrophobicContact CD1-CD1 4.38Å; I153-I165 HydrophobicContact CD1-CG2 3.44Å; I153-I165 VanDerWaalsContact CD1-CG2 3.44Å; W161-I165 WeakPolarHBondContact O-CG2 3.44Å; W161-I165 PolarHBondContact O-N 3.37Å; W161-I165 VanDerWaalsContact O-N 3.09Å; L162-I165 WeakPolarHBondContact O-CD1 3.35Å; L162-I165 VanDerWaalsContact O-CG1 3.25Å; L162-I165 WeakPolarHBondContact O-CG1 3.46Å; F163-I165 VanDerWaalsContact C-N 3.27Å; F163-I165 PolarHBondContact O-N 3.14Å; I165-I167 VanDerWaalsContact C-N 3.3Å; I165-I167 PolarHBondContact O-N 3.39Å; I165-P168 WeakPolarHBondContact O-CD 3.38Å; I165-I169 WeakPolarHBondContact O-CD1 3.43Å; I165-I169 WeakPolarHBondContact O-CG1 3.1Å
166N93.6Very high96.1Very high4 Ų447.7 Ų47.72%0.02124%0.239CC..Hα-helixtrans-74.6-23.6179.9-73.7-44.2000112.2F81 F163 Y164 I169 A170F81-N166 HydrophobicContact CE1-CB 3.82Å; F163-N166 WeakPolarHBondContact O-CB 3.49Å; F163-N166 PolarHBondContact O-N 3.3Å; F163-N166 VanDerWaalsContact O-N 3.16Å; Y164-N166 PolarHBondContact O-N 3.28Å; Y164-N166 VanDerWaalsContact O-N 3.09Å; N166-I169 PolarHBondContact O-N 2.84Å; N166-A170 VanDerWaalsContact O-CB 3.25Å; N166-A170 WeakPolarHBondContact O-CB 3.23Å; N166-A170 PolarHBondContact O-N 3.07Å
167I96.3Very high96.3Very high36 Ų3639.6 Ų39.619%0.18520%0.204CC..Hα-helixtrans-66-50.9-174.1-54.1-60.1000111.7S82 F86 Y164 I165 I169 A170 I171S82-I167 WeakPolarHBondContact O-CD1 3.25Å; F86-I167 HydrophobicContact CB-CD1 3.96Å; Y164-I167 WeakPolarHBondContact O-CB 3.21Å; Y164-I167 PolarHBondContact O-N 3.29Å; I165-I167 VanDerWaalsContact C-N 3.3Å; I165-I167 PolarHBondContact O-N 3.39Å; I167-I169 VanDerWaalsContact C-N 3.29Å; I167-I169 PolarHBondContact O-N 3.02Å; I167-A170 PolarHBondContact O-N 3.37Å; I167-I171 HydrophobicContact CG2-CD1 3.94Å; I167-I171 VanDerWaalsContact O-CG1 3.3Å; I167-I171 WeakPolarHBondContact O-CG1 3.32Å; I167-I171 PolarHBondContact O-N 2.91Å
168P96.9Very high96.5Very high75 Ų7541.4 Ų41.449%0.48721%0.208SC..Hα-helixtrans-59-40.3174.5-23.934.4000112.7Y164 I165 I171 I172Y164-P168 WeakPolarHBondContact O-CD 3.4Å; I165-P168 WeakPolarHBondContact O-CD 3.38Å; P168-I171 PolarHBondContact O-N 3.34Å; P168-I172 VanDerWaalsContact O-CG1 3.3Å; P168-I172 WeakPolarHBondContact O-CG1 3.41Å; P168-I172 PolarHBondContact O-N 2.9Å
169I96.3Very high96.5Very high36 Ų3645.7 Ų45.719%0.18522%0.216CC..Hα-helixtrans-64.3-43.5-180-56.9173.4000110.4L14 F17 M18 I165 N166 I167 I172 A173L14-I169 HydrophobicContact CB-CG2 4.13Å; L14-I169 HydrophobicContact CD2-CG2 4.06Å; L14-I169 HydrophobicContact CG-CG2 4.45Å; F17-I169 HydrophobicContact CD1-CD1 4.22Å; F17-I169 HydrophobicContact CE1-CD1 3.88Å; M18-I169 HydrophobicContact CG-CB 4.19Å; M18-I169 HydrophobicContact CG-CG2 3.61Å; M18-I169 HydrophobicContact SD-CB 4.15Å; M18-I169 HydrophobicContact SD-CG2 3.64Å; I165-I169 WeakPolarHBondContact O-CD1 3.43Å; I165-I169 WeakPolarHBondContact O-CG1 3.1Å; N166-I169 PolarHBondContact O-N 2.84Å; I167-I169 VanDerWaalsContact C-N 3.29Å; I167-I169 PolarHBondContact O-N 3.02Å; I169-I172 PolarHBondContact O-N 3.49Å; I169-A173 WeakPolarHBondContact O-CB 3.3Å; I169-A173 PolarHBondContact O-N 2.97Å
170A97.4Very high96.4Very high0 Ų045.6 Ų45.60%022%0.215CC..Hα-helixtrans-65.4-41.5178.300000112M18 S82 N166 I167 I172 A173 I174M18-A170 HydrophobicContact CE-CB 3.49Å; M18-A170 VanDerWaalsContact CE-CB 3.49Å; M18-A170 HydrophobicContact SD-CB 4.14Å; S82-A170 WeakPolarHBondContact OG-CB 3.21Å; N166-A170 VanDerWaalsContact O-CB 3.25Å; N166-A170 WeakPolarHBondContact O-CB 3.23Å; N166-A170 PolarHBondContact O-N 3.07Å; I167-A170 PolarHBondContact O-N 3.37Å; A170-I172 VanDerWaalsContact C-N 3.34Å; A170-I172 PolarHBondContact O-N 3.17Å; A170-A173 PolarHBondContact O-N 3.48Å; A170-I174 VanDerWaalsContact O-CG1 3.27Å; A170-I174 WeakPolarHBondContact O-CG1 3.18Å; A170-I174 PolarHBondContact O-N 2.87Å
171I97.8Very high96.2Very high89 Ų8943.9 Ų43.946%0.45621%0.208SC..Hα-helixtrans-59.9-46.6175.5-69.1165.9000110.2I167 P168 A173 I174 I175I167-I171 HydrophobicContact CG2-CD1 3.94Å; I167-I171 VanDerWaalsContact O-CG1 3.3Å; I167-I171 WeakPolarHBondContact O-CG1 3.32Å; I167-I171 PolarHBondContact O-N 2.91Å; P168-I171 PolarHBondContact O-N 3.34Å; I171-A173 PolarHBondContact O-N 2.81Å; I171-I174 PolarHBondContact O-N 3.33Å; I171-I175 HydrophobicContact CG2-CD1 4.18Å; I171-I175 WeakPolarHBondContact O-CG1 3.45Å; I171-I175 PolarHBondContact O-N 2.55Å; I171-I175 VanDerWaalsContact O-N 3.09Å
172I98.2Very high96Very high87 Ų8742 Ų4245%0.44620%0.204SC..Hα-helixtrans-60.3-47.9175.6-65.2165.1000109.8L14 P168 I169 A170 I174 I175 L176L14-I172 HydrophobicContact CD1-CB 4.23Å; L14-I172 HydrophobicContact CD1-CG2 3.65Å; P168-I172 VanDerWaalsContact O-CG1 3.3Å; P168-I172 WeakPolarHBondContact O-CG1 3.41Å; P168-I172 PolarHBondContact O-N 2.9Å; I169-I172 PolarHBondContact O-N 3.49Å; A170-I172 VanDerWaalsContact C-N 3.34Å; A170-I172 PolarHBondContact O-N 3.17Å; I172-I174 VanDerWaalsContact C-N 3.3Å; I172-I174 PolarHBondContact O-N 3.08Å; I172-I175 PolarHBondContact O-N 3.47Å; I172-I175 VanDerWaalsContact O-N 3.13Å; I172-L176 HydrophobicContact CG2-CD1 4.02Å; I172-L176 HydrophobicContact CG2-CG 4.27Å; I172-L176 VanDerWaalsContact O-CG 3.32Å; I172-L176 WeakPolarHBondContact O-CG 3.27Å; I172-L176 PolarHBondContact O-N 3.45Å
173A97.8Very high95.7Very high0 Ų042.9 Ų42.90%021%0.208CC..Hα-helixtrans-58.3-40.117800000112.4L14 L78 I169 A170 I171 I175 L176 V177L14-A173 HydrophobicContact CB-CB 4.21Å; L14-A173 HydrophobicContact CD1-CB 4.41Å; L78-A173 HydrophobicContact CD1-CB 4.18Å; L78-A173 HydrophobicContact CD2-CB 3.84Å; I169-A173 WeakPolarHBondContact O-CB 3.3Å; I169-A173 PolarHBondContact O-N 2.97Å; A170-A173 PolarHBondContact O-N 3.48Å; I171-A173 PolarHBondContact O-N 2.81Å; A173-I175 PolarHBondContact O-N 3.37Å; A173-L176 PolarHBondContact O-N 3.42Å; A173-V177 WeakPolarHBondContact O-CB 3.33Å; A173-V177 VanDerWaalsContact O-CG2 3.28Å; A173-V177 WeakPolarHBondContact O-CG2 3.33Å; A173-V177 PolarHBondContact O-N 2.85Å
174I98.2Very high94.7Very high27 Ų2747.9 Ų47.914%0.13824%0.241CC..Hα-helixtrans-59.8-47.4175.6-71.3167.6000110.2L78 L79 A170 I171 I172 L176 V177 I178L78-I174 HydrophobicContact CB-CD1 4.07Å; L78-I174 HydrophobicContact CB-CG1 3.58Å; L78-I174 HydrophobicContact CD1-CB 4.31Å; L78-I174 HydrophobicContact CD1-CG1 3.61Å; L78-I174 HydrophobicContact CG-CG1 4.14Å; L79-I174 HydrophobicContact CD2-CD1 4.05Å; A170-I174 VanDerWaalsContact O-CG1 3.27Å; A170-I174 WeakPolarHBondContact O-CG1 3.18Å; A170-I174 PolarHBondContact O-N 2.87Å; I171-I174 PolarHBondContact O-N 3.33Å; I172-I174 VanDerWaalsContact C-N 3.3Å; I172-I174 PolarHBondContact O-N 3.08Å; I174-L176 PolarHBondContact O-N 3.47Å; I174-V177 PolarHBondContact O-N 3.22Å; I174-I178 HydrophobicContact CG2-CD1 3.72Å; I174-I178 HydrophobicContact CG2-CG1 4.39Å; I174-I178 VanDerWaalsContact O-CG1 3.28Å; I174-I178 WeakPolarHBondContact O-CG1 3.4Å; I174-I178 PolarHBondContact O-N 3.38Å
175I98.1Very high93.3Very high71 Ų7151.7 Ų51.736%0.36426%0.26SS..Hα-helixtrans-59.6-46.8178.5-64.9164.9000110.6I171 I172 A173 V177 I178 W179I171-I175 HydrophobicContact CG2-CD1 4.18Å; I171-I175 WeakPolarHBondContact O-CG1 3.45Å; I171-I175 PolarHBondContact O-N 2.55Å; I171-I175 VanDerWaalsContact O-N 3.09Å; I172-I175 PolarHBondContact O-N 3.47Å; I172-I175 VanDerWaalsContact O-N 3.13Å; A173-I175 PolarHBondContact O-N 3.37Å; I175-V177 PolarHBondContact O-N 2.91Å; I175-I178 PolarHBondContact O-N 3.33Å; I175-W179 HydrophobicContact CG2-CD2 4.05Å; I175-W179 HydrophobicContact CG2-CE3 4.15Å; I175-W179 HydrophobicContact CG2-CH2 3.75Å; I175-W179 HydrophobicContact CG2-CZ2 3.62Å; I175-W179 HydrophobicContact CG2-CZ3 4Å; I175-W179 PolarHBondContact O-N 3.02Å; I175-W179 VanDerWaalsContact O-N 3.1Å
176L97.7Very high91.9Very high21 Ų2151.2 Ų51.211%0.1126%0.257CS..Hα-helixtrans-67.2-36.2-179.6-56.4175.7000112.4I7 I10 A11 L14 I172 A173 I174 W179 T180I7-L176 HydrophobicContact CG2-CB 4.06Å; I7-L176 HydrophobicContact CG2-CD2 3.7Å; I7-L176 HydrophobicContact CG2-CG 4.36Å; I10-L176 HydrophobicContact CB-CD1 4.24Å; I10-L176 HydrophobicContact CG2-CD1 3.62Å; A11-L176 HydrophobicContact CB-CB 3.84Å; A11-L176 HydrophobicContact CB-CD1 4.39Å; L14-L176 HydrophobicContact CD1-CD1 3.89Å; I172-L176 HydrophobicContact CG2-CD1 4.02Å; I172-L176 HydrophobicContact CG2-CG 4.27Å; I172-L176 VanDerWaalsContact O-CG 3.32Å; I172-L176 WeakPolarHBondContact O-CG 3.27Å; I172-L176 PolarHBondContact O-N 3.45Å; A173-L176 PolarHBondContact O-N 3.42Å; I174-L176 PolarHBondContact O-N 3.47Å; L176-W179 HydrophobicContact CD2-CE3 4.43Å; L176-W179 PolarHBondContact O-N 3.47Å; L176-T180 WeakPolarHBondContact O-CB 3.1Å; L176-T180 PolarHBondContact O-N 3.31Å; L176-T180 PolarHBondContact O-OG1 3.24Å
177V97Very high89.9Confident0 Ų059.6 Ų59.60%030%0.296CS..Hα-helixtrans-63.4-49173.8162.70000110.2A11 I15 I71 A74 I75 L78 A173 I174 I175 W179 T180 F181A11-V177 HydrophobicContact CB-CG2 4.48Å; I15-V177 HydrophobicContact CD1-CG2 4.19Å; I71-V177 HydrophobicContact CG1-CG1 4.4Å; A74-V177 HydrophobicContact CB-CG1 3.7Å; I75-V177 HydrophobicContact CG1-CG1 4.15Å; L78-V177 HydrophobicContact CD1-CB 4.34Å; L78-V177 HydrophobicContact CD1-CG2 3.9Å; A173-V177 WeakPolarHBondContact O-CB 3.33Å; A173-V177 VanDerWaalsContact O-CG2 3.28Å; A173-V177 WeakPolarHBondContact O-CG2 3.33Å; A173-V177 PolarHBondContact O-N 2.85Å; I174-V177 PolarHBondContact O-N 3.22Å; I175-V177 PolarHBondContact O-N 2.91Å; V177-W179 PolarHBondContact O-N 2.78Å; V177-T180 PolarHBondContact O-N 3.32Å; V177-T180 VanDerWaalsContact O-N 3.12Å; V177-F181 HydrophobicContact CB-CD2 4.45Å; V177-F181 HydrophobicContact CB-CG 4.37Å; V177-F181 HydrophobicContact CG1-CB 4.06Å; V177-F181 HydrophobicContact CG1-CD2 3.85Å; V177-F181 HydrophobicContact CG1-CE2 4.45Å; V177-F181 HydrophobicContact CG1-CG 3.95Å; V177-F181 HydrophobicContact CG2-CD1 4.29Å; V177-F181 HydrophobicContact CG2-CD2 4.06Å; V177-F181 HydrophobicContact CG2-CE1 4.12Å; V177-F181 HydrophobicContact CG2-CE2 3.88Å; V177-F181 HydrophobicContact CG2-CG 4.26Å; V177-F181 HydrophobicContact CG2-CZ 3.92Å; V177-F181 WeakPolarHBondContact O-CB 3.35Å; V177-F181 PolarHBondContact O-N 3.31Å
178I96.6Very high87.8Confident75 Ų7562.3 Ų62.339%0.38532%0.315SS..Hα-helixtrans-55.9-37.8177.3-70.2166.5000110.8I75 I174 I175 H182I75-I178 HydrophobicContact CD1-CD1 4.31Å; I75-I178 HydrophobicContact CD1-CG1 3.71Å; I75-I178 HydrophobicContact CG1-CG1 4.39Å; I174-I178 HydrophobicContact CG2-CD1 3.72Å; I174-I178 HydrophobicContact CG2-CG1 4.39Å; I174-I178 VanDerWaalsContact O-CG1 3.28Å; I174-I178 WeakPolarHBondContact O-CG1 3.4Å; I174-I178 PolarHBondContact O-N 3.38Å; I175-I178 PolarHBondContact O-N 3.33Å; I178-H182 PolarHBondContact O-CE1 3.33Å
179W94.5Very high85.8Confident166 Ų16663.1 Ų63.163%0.62932%0.318SS*.Hα-helixtrans-78-29.5180-67.2-14.4000114.4I175 L176 V177I175-W179 HydrophobicContact CG2-CD2 4.05Å; I175-W179 HydrophobicContact CG2-CE3 4.15Å; I175-W179 HydrophobicContact CG2-CH2 3.75Å; I175-W179 HydrophobicContact CG2-CZ2 3.62Å; I175-W179 HydrophobicContact CG2-CZ3 4Å; I175-W179 PolarHBondContact O-N 3.02Å; I175-W179 VanDerWaalsContact O-N 3.1Å; L176-W179 HydrophobicContact CD2-CE3 4.43Å; L176-W179 PolarHBondContact O-N 3.47Å; V177-W179 PolarHBondContact O-N 2.78Å
180T94.2Very high83.9Confident1 Ų162.9 Ų62.91%0.00632%0.322CS..Hα-helixtrans-119.3-24.3-164.663.40000116.8K4 I7 T8 L176 V177 H182K4-T180 WeakPolarHBondContact CE-O 3.32Å; K4-T180 HydrophobicContact CG-CG2 4.06Å; I7-T180 HydrophobicContact CB-CG2 3.62Å; I7-T180 HydrophobicContact CG2-CG2 3.27Å; T8-T180 VanDerWaalsContact OG1-CB 3.32Å; T8-T180 WeakPolarHBondContact OG1-CB 3.42Å; L176-T180 WeakPolarHBondContact O-CB 3.1Å; L176-T180 PolarHBondContact O-N 3.31Å; L176-T180 PolarHBondContact O-OG1 3.24Å; V177-T180 PolarHBondContact O-N 3.32Å; V177-T180 VanDerWaalsContact O-N 3.12Å; T180-H182 PolarHBondContact O-N 3.5Å
181F92.9Very high82.2Confident0 Ų073.1 Ų73.10%037%0.366CS..  trans-82.551.3-174.2-80.230.6000111.9T8 A11 L12 I15 I70 I71 A74 V118 V177 F183T8-F181 HydrophobicContact CG2-CE1 4.1Å; A11-F181 HydrophobicContact CB-CE1 4.18Å; L12-F181 HydrophobicContact CD2-CZ 4.29Å; I15-F181 HydrophobicContact CD1-CZ 4.19Å; I70-F181 HydrophobicContact CG1-CD2 4.5Å; I70-F181 HydrophobicContact CG2-CB 4.2Å; I71-F181 HydrophobicContact CB-CB 4.49Å; A74-F181 HydrophobicContact CB-CD2 3.81Å; A74-F181 HydrophobicContact CB-CE2 4Å; V118-F181 HydrophobicContact CB-CZ 4.44Å; V118-F181 HydrophobicContact CG1-CE1 4.04Å; V118-F181 HydrophobicContact CG1-CE2 4.48Å; V118-F181 HydrophobicContact CG1-CZ 3.94Å; V118-F181 HydrophobicContact CG2-CD2 4.27Å; V118-F181 HydrophobicContact CG2-CE2 3.63Å; V118-F181 HydrophobicContact CG2-CZ 3.83Å; V177-F181 HydrophobicContact CB-CD2 4.45Å; V177-F181 HydrophobicContact CB-CG 4.37Å; V177-F181 HydrophobicContact CG1-CB 4.06Å; V177-F181 HydrophobicContact CG1-CD2 3.85Å; V177-F181 HydrophobicContact CG1-CE2 4.45Å; V177-F181 HydrophobicContact CG1-CG 3.95Å; V177-F181 HydrophobicContact CG2-CD1 4.29Å; V177-F181 HydrophobicContact CG2-CD2 4.06Å; V177-F181 HydrophobicContact CG2-CE1 4.12Å; V177-F181 HydrophobicContact CG2-CE2 3.88Å; V177-F181 HydrophobicContact CG2-CG 4.26Å; V177-F181 HydrophobicContact CG2-CZ 3.92Å; V177-F181 WeakPolarHBondContact O-CB 3.35Å; V177-F181 PolarHBondContact O-N 3.31Å; F181-F183 HydrophobicContact CB-CE2 4.18Å; F181-F183 HydrophobicContact CD1-CZ 4.3Å; F181-F183 HydrophobicContact CG-CE2 4.26Å; F181-F183 HydrophobicContact CG-CZ 4.47Å
182H90.9Very high80.6Confident99 Ų9970.4 Ų70.446%0.45836%0.355SS..  trans-118.7101.7174.6-60.5109.9000107.7K4 I178 T180K4-H182 PolarHBondContact NZ-O 2.83Å; I178-H182 PolarHBondContact O-CE1 3.33Å; T180-H182 PolarHBondContact O-N 3.5Å
183F88.5Confident79.6Confident22 Ų2275.3 Ų75.310%0.09637%0.373CS..  trans-113.4138.5-178.6-51.8-70.8000111.3I70 V118 L121 A122 F181 E185 E186I70-F183 HydrophobicContact CD1-CE2 4.35Å; I70-F183 HydrophobicContact CG2-CD2 3.78Å; I70-F183 HydrophobicContact CG2-CE2 3.89Å; V118-F183 HydrophobicContact CG1-CE2 4.38Å; V118-F183 HydrophobicContact CG1-CZ 3.94Å; L121-F183 HydrophobicContact CB-CB 4.37Å; L121-F183 HydrophobicContact CB-CD1 4.18Å; L121-F183 HydrophobicContact CB-CD2 4.04Å; L121-F183 HydrophobicContact CB-CE2 4.42Å; L121-F183 HydrophobicContact CB-CG 3.92Å; L121-F183 HydrophobicContact CD1-CD2 4.1Å; A122-F183 HydrophobicContact CB-CD1 4.48Å; A122-F183 HydrophobicContact CB-CE1 3.62Å; A122-F183 HydrophobicContact CB-CZ 4.09Å; F181-F183 HydrophobicContact CB-CE2 4.18Å; F181-F183 HydrophobicContact CD1-CZ 4.3Å; F181-F183 HydrophobicContact CG-CE2 4.26Å; F181-F183 HydrophobicContact CG-CZ 4.47Å; F183-E185 VanDerWaalsContact C-N 3.31Å; F183-E185 PolarHBondContact O-N 2.86Å; F183-E186 HydrophobicContact CB-CG 4.37Å; F183-E186 PolarHBondContact N-OE1 3.13Å; F183-E186 WeakPolarHBondContact O-CG 3.36Å; F183-E186 PolarHBondContact O-N 3.27Å
184P75.8Confident78.8Confident107 Ų10779.4 Ų79.470%0.69539%0.391SS*.G310 helixtrans-62-35.1-177.3-22.232.9000113.7E186P184-E186 PolarHBondContact O-N 3.26Å
185E65.8Low78.3Confident133 Ų13379 Ų7962%0.62139%0.389SS*.G310 helixtrans-76.914.1-174.2-63.4130.9-159.100114F183 E187F183-E185 VanDerWaalsContact C-N 3.31Å; F183-E185 PolarHBondContact O-N 2.86Å; E185-E187 PolarHBondContact O-N 3.1Å
186E65.8Low77.8Confident26 Ų2679.9 Ų79.912%0.12140%0.398CS..G310 helixtrans-77.6-1178.2-73.6-180-136.100113.9K69 I70 F183 P184 T188K69-E186 WeakPolarHBondContact CA-OE2 3.46Å; K69-E186 WeakPolarHBondContact CB-OE2 3.25Å; I70-E186 WeakPolarHBondContact CG2-OE1 3.49Å; I70-E186 PolarHBondContact N-OE2 2.87Å; F183-E186 HydrophobicContact CB-CG 4.37Å; F183-E186 PolarHBondContact N-OE1 3.13Å; F183-E186 WeakPolarHBondContact O-CG 3.36Å; F183-E186 PolarHBondContact O-N 3.27Å; P184-E186 PolarHBondContact O-N 3.26Å; E186-T188 VanDerWaalsContact C-N 3.26Å; E186-T188 PolarHBondContact O-N 2.82Å
187E50.8Low77.5Confident180 Ų18084.8 Ų84.884%0.84142%0.419SS*.  trans-66.7-0.7-161.4-78.3-166.3163.900118.3E185E185-E187 PolarHBondContact O-N 3.1Å
188T52.8Low77.3Confident94 Ų9484.8 Ų84.858%0.57742%0.419SS*.  trans-116.983.1177.856.60000111.8E186 A190E186-T188 VanDerWaalsContact C-N 3.26Å; E186-T188 PolarHBondContact O-N 2.82Å; T188-A190 PolarHBondContact O-N 2.69Å
189V54.5Low77.1Confident91 Ų9182.5 Ų82.555%0.55241%0.407SS*.  trans-61.895.4152.1175.30000105.6S66 R67 K191S66-V189 WeakPolarHBondContact O-CA 3.16Å; R67-V189 WeakPolarHBondContact O-CG1 3.42Å; R67-V189 WeakPolarHBondContact O-CG2 3.32Å; V189-K191 PolarHBondContact O-N 2.82Å; V189-K191 VanDerWaalsContact O-N 3.11Å
190A57.5Low77Confident31 Ų3178.4 Ų78.426%0.25640%0.401SS..  trans-61.6119.7-179.700000107.7S66 T188 S192S66-A190 PolarHBondContact O-N 3.49Å; T188-A190 PolarHBondContact O-N 2.69Å; A190-S192 PolarHBondContact O-N 3.42Å
191K60.2Low77.1Confident215 Ų21580 Ų8094%0.93541%0.409SS*.  trans-69.728168-69.7-172.9178.9179.40111.9V189V189-K191 PolarHBondContact O-N 2.82Å; V189-K191 VanDerWaalsContact O-N 3.11Å
192S65.9Low77.1Confident33 Ų3380.3 Ų80.323%0.23141%0.41CS..PPolyproline II helixtrans-83.2147.3-175.1-164.80000111.8R67 A190 S245R67-S192 PolarHBondContact NH1-O 3.28Å; R67-S192 PolarHBondContact NH2-O 3.28Å; A190-S192 PolarHBondContact O-N 3.42Å; S192-S245 WeakPolarHBondContact CB-OG 3.07Å; S192-S245 WeakPolarHBondContact OG-CB 3.36Å; S192-S245 PolarHBondContact OG-OG 3.34Å
193K75.9Confident77.2Confident189 Ų18978 Ų7882%0.82240%0.398SS*.PPolyproline II helixtrans-61.6138.1175.5-68-175.3178.6-178.70109.3D195K193-D195 PolarHBondContact O-N 2.83Å
194F81.3Confident77.6Confident86 Ų8680.3 Ų80.338%0.37741%0.414SS..PPolyproline II helixtrans-74.6121.8176.8-171.6-97.8000109.1E63 R67 T196 L199E63-F194 HydrophobicContact CG-CD2 3.9Å; E63-F194 HydrophobicContact CG-CE2 3.53Å; E63-F194 WeakPolarHBondContact OE1-CD2 3.41Å; R67-F194 VanDerWaalsContact NH2-CA 3.29Å; F194-T196 VanDerWaalsContact C-N 3.3Å; F194-T196 HydrophobicContact CD1-CG2 3.64Å; F194-T196 HydrophobicContact CE1-CG2 4.17Å; F194-T196 PolarHBondContact O-N 3.31Å; F194-L199 HydrophobicContact CE1-CD1 3.83Å; F194-L199 HydrophobicContact CE2-CD1 4.36Å; F194-L199 HydrophobicContact CZ-CD1 3.43Å; F194-L199 VanDerWaalsContact CZ-CD1 3.43Å
195D87.4Confident78.5Confident18 Ų1877.3 Ų77.310%0.09639%0.389CS..  trans-7882.5177.6-177.715.5000110.9K193 K197 G198 L199 V243 F247K193-D195 PolarHBondContact O-N 2.83Å; D195-K197 PolarHBondContact O-N 3.03Å; D195-K197 PolarHBondContact OD1-N 3.08Å; D195-G198 VanDerWaalsContact CG-N 3.29Å; D195-G198 PolarHBondContact OD1-N 3.31Å; D195-G198 VanDerWaalsContact OD2-CA 3.25Å; D195-G198 WeakPolarHBondContact OD2-CA 3.44Å; D195-G198 PolarHBondContact OD2-N 2.9Å; D195-L199 VanDerWaalsContact O-CB 3.25Å; D195-L199 WeakPolarHBondContact O-CB 3.3Å; D195-L199 PolarHBondContact O-N 3.35Å; D195-V243 HydrophobicContact CB-CG1 4.3Å; D195-F247 HydrophobicContact CB-CB 4.33Å; D195-F247 PolarHBondContact OD2-N 3.42Å
196T88.6Confident79.7Confident90 Ų9071.1 Ų71.155%0.55236%0.361SS*.Hα-helixtrans-62-31.5176.453.20000112.2F194 T200F194-T196 VanDerWaalsContact C-N 3.3Å; F194-T196 HydrophobicContact CD1-CG2 3.64Å; F194-T196 HydrophobicContact CE1-CG2 4.17Å; F194-T196 PolarHBondContact O-N 3.31Å; T196-T200 WeakPolarHBondContact O-CB 3.31Å; T196-T200 PolarHBondContact O-N 3.01Å; T196-T200 PolarHBondContact O-OG1 3.16Å
197K91.3Very high80.9Confident125 Ų12571.8 Ų71.854%0.54337%0.374SS..Hα-helixtrans-75.6-49.7-176.5-172.2179.7177.9-177.40110.8D195 L199 T200 L201 V239D195-K197 PolarHBondContact O-N 3.03Å; D195-K197 PolarHBondContact OD1-N 3.08Å; K197-L199 VanDerWaalsContact C-N 3.34Å; K197-T200 PolarHBondContact O-N 3.41Å; K197-L201 HydrophobicContact CG-CD1 4.3Å; K197-L201 WeakPolarHBondContact O-CG 3.19Å; K197-L201 PolarHBondContact O-N 3.42Å; K197-V239 HydrophobicContact CD-CG1 3.89Å; K197-V239 HydrophobicContact CG-CG1 4.21Å
198G92.2Very high82.9Confident0 Ų064.4 Ų64.40%034%0.341CS..Hα-helixtrans-58.6-46173.800000111.4D195 T200 L201 F202 L236 E240D195-G198 VanDerWaalsContact CG-N 3.29Å; D195-G198 PolarHBondContact OD1-N 3.31Å; D195-G198 VanDerWaalsContact OD2-CA 3.25Å; D195-G198 WeakPolarHBondContact OD2-CA 3.44Å; D195-G198 PolarHBondContact OD2-N 2.9Å; G198-T200 PolarHBondContact O-N 3.49Å; G198-L201 PolarHBondContact O-N 3.28Å; G198-F202 VanDerWaalsContact O-CB 3.24Å; G198-F202 WeakPolarHBondContact O-CB 3.38Å; G198-F202 PolarHBondContact O-N 3.38Å; G198-L236 WeakPolarHBondContact O-CD1 3.27Å; G198-E240 WeakPolarHBondContact CA-OE1 3.38Å
199L92.3Very high84.7Confident27 Ų2761.1 Ų61.114%0.14132%0.319CS..Hα-helixtrans-58.3-46.7175.6-178142.1000112.8I60 F194 D195 K197 F202 Y203 F247I60-L199 HydrophobicContact CD1-CD1 4.48Å; F194-L199 HydrophobicContact CE1-CD1 3.83Å; F194-L199 HydrophobicContact CE2-CD1 4.36Å; F194-L199 HydrophobicContact CZ-CD1 3.43Å; F194-L199 VanDerWaalsContact CZ-CD1 3.43Å; D195-L199 VanDerWaalsContact O-CB 3.25Å; D195-L199 WeakPolarHBondContact O-CB 3.3Å; D195-L199 PolarHBondContact O-N 3.35Å; K197-L199 VanDerWaalsContact C-N 3.34Å; L199-F202 WeakPolarHBondContact O-CB 3.09Å; L199-F202 PolarHBondContact O-N 3.44Å; L199-Y203 HydrophobicContact CD1-CE2 4.07Å; L199-Y203 HydrophobicContact CD2-CD2 3.66Å; L199-Y203 HydrophobicContact CD2-CE2 3.86Å; L199-Y203 HydrophobicContact CG-CD2 3.74Å; L199-Y203 HydrophobicContact CG-CE2 3.68Å; L199-Y203 VanDerWaalsContact O-CD2 3.26Å; L199-Y203 WeakPolarHBondContact O-CD2 3.48Å; L199-Y203 PolarHBondContact O-N 3.42Å; L199-F247 HydrophobicContact CB-CD2 4.27Å; L199-F247 HydrophobicContact CB-CG 4.19Å; L199-F247 HydrophobicContact CD1-CD2 4.13Å; L199-F247 HydrophobicContact CD1-CE2 3.88Å; L199-F247 HydrophobicContact CD1-CZ 4.35Å; L199-F247 HydrophobicContact CG-CE2 4.49Å
200T93.4Very high86.3Confident80 Ų8057.3 Ų57.349%0.49130%0.296SS..Hα-helixtrans-63.5-48179.9-58.40000111T196 K197 G198 F202 Y203 V204T196-T200 WeakPolarHBondContact O-CB 3.31Å; T196-T200 PolarHBondContact O-N 3.01Å; T196-T200 PolarHBondContact O-OG1 3.16Å; K197-T200 PolarHBondContact O-N 3.41Å; G198-T200 PolarHBondContact O-N 3.49Å; T200-F202 VanDerWaalsContact C-N 3.27Å; T200-F202 PolarHBondContact O-N 3.12Å; T200-Y203 PolarHBondContact O-N 3.48Å; T200-V204 VanDerWaalsContact O-CG2 3.32Å; T200-V204 WeakPolarHBondContact O-CG2 3.47Å; T200-V204 PolarHBondContact O-N 3.15Å
201L94.6Very high87.7Confident34 Ų3460.1 Ų60.118%0.17830%0.302CS..Hα-helixtrans-60.6-38.8177.3-73.1172.6000111.7K197 G198 V204 F205 V232 L236 V239K197-L201 HydrophobicContact CG-CD1 4.3Å; K197-L201 WeakPolarHBondContact O-CG 3.19Å; K197-L201 PolarHBondContact O-N 3.42Å; G198-L201 PolarHBondContact O-N 3.28Å; L201-V204 PolarHBondContact O-N 3.03Å; L201-F205 WeakPolarHBondContact O-CB 3.18Å; L201-F205 PolarHBondContact O-N 2.92Å; L201-V232 HydrophobicContact CD2-CG1 4.38Å; L201-V232 WeakPolarHBondContact O-CG1 3.46Å; L201-L236 HydrophobicContact CB-CB 4.27Å; L201-L236 HydrophobicContact CB-CD1 3.81Å; L201-V239 HydrophobicContact CD1-CB 4.18Å; L201-V239 HydrophobicContact CD1-CG1 4.39Å; L201-V239 HydrophobicContact CD1-CG2 3.88Å
202F93.7Very high89Confident6 Ų650.1 Ų50.13%0.02626%0.259CS..Hα-helixtrans-62.7-47.2176.8-169.8-86.5000112.1P59 G198 L199 T200 F205 I206 L236 F247 L248 F385 L388P59-F202 HydrophobicContact CB-CD1 4.32Å; P59-F202 HydrophobicContact CB-CE1 3.7Å; P59-F202 HydrophobicContact CB-CZ 4.24Å; P59-F202 HydrophobicContact CG-CD1 4.36Å; P59-F202 HydrophobicContact CG-CE1 3.49Å; P59-F202 VanDerWaalsContact CG-CE1 3.49Å; P59-F202 HydrophobicContact CG-CZ 4.17Å; G198-F202 VanDerWaalsContact O-CB 3.24Å; G198-F202 WeakPolarHBondContact O-CB 3.38Å; G198-F202 PolarHBondContact O-N 3.38Å; L199-F202 WeakPolarHBondContact O-CB 3.09Å; L199-F202 PolarHBondContact O-N 3.44Å; T200-F202 VanDerWaalsContact C-N 3.27Å; T200-F202 PolarHBondContact O-N 3.12Å; F202-F205 WeakPolarHBondContact O-CB 3.39Å; F202-F205 PolarHBondContact O-N 3.3Å; F202-I206 HydrophobicContact CD1-CG1 3.91Å; F202-I206 HydrophobicContact CE1-CD1 4.12Å; F202-I206 HydrophobicContact CE1-CG1 3.45Å; F202-I206 VanDerWaalsContact CE1-CG1 3.45Å; F202-I206 HydrophobicContact CZ-CD1 4.17Å; F202-I206 HydrophobicContact CZ-CG1 3.98Å; F202-I206 WeakPolarHBondContact O-CG1 3.23Å; F202-I206 PolarHBondContact O-N 2.93Å; F202-L236 HydrophobicContact CB-CD1 4.44Å; F202-L236 HydrophobicContact CB-CD2 4.36Å; F202-L236 HydrophobicContact CD2-CD2 3.78Å; F202-F247 HydrophobicContact CB-CD1 4.03Å; F202-F247 HydrophobicContact CB-CE1 4.02Å; F202-F247 AromaticContact CD1-CE1 3.81Å; F202-F247 HydrophobicContact CD1-CE1 3.81Å; F202-F247 HydrophobicContact CD2-CD1 4.39Å; F202-F247 HydrophobicContact CD2-CE1 4.24Å; F202-F247 HydrophobicContact CE1-CE1 4.39Å; F202-F247 HydrophobicContact CG-CD1 4.08Å; F202-F247 AromaticContact CG-CE1 3.74Å; F202-F247 HydrophobicContact CG-CE1 3.74Å; F202-L248 HydrophobicContact CD2-CD2 4.36Å; F202-L248 HydrophobicContact CE2-CD2 4.28Å; F202-F385 HydrophobicContact CD2-CE1 4.11Å; F202-F385 HydrophobicContact CE1-CE1 4.13Å; F202-F385 AromaticContact CE2-CD1 3.86Å; F202-F385 HydrophobicContact CE2-CD1 3.86Å; F202-F385 AromaticContact CE2-CE1 3.48Å; F202-F385 HydrophobicContact CE2-CE1 3.48Å; F202-F385 VanDerWaalsContact CE2-CE1 3.48Å; F202-F385 HydrophobicContact CE2-CZ 4.49Å; F202-F385 AromaticContact CZ-CD1 3.68Å; F202-F385 HydrophobicContact CZ-CD1 3.68Å; F202-F385 AromaticContact CZ-CE1 3.49Å; F202-F385 HydrophobicContact CZ-CE1 3.49Å; F202-F385 VanDerWaalsContact CZ-CE1 3.49Å; F202-L388 HydrophobicContact CE1-CD2 3.83Å; F202-L388 HydrophobicContact CZ-CD2 3.39Å
203Y93.9Very high89.8Confident52 Ų5249.8 Ų49.820%0.20426%0.255CS..Hα-helixtrans-69.9-32.1178.5-80.8-64.4000113.3I56 L199 T200 G207I56-Y203 HydrophobicContact CB-CE1 4.12Å; I56-Y203 HydrophobicContact CG1-CE1 4.44Å; I56-Y203 HydrophobicContact CG2-CD1 4.2Å; I56-Y203 HydrophobicContact CG2-CE1 3.54Å; I56-Y203 VanDerWaalsContact O-CE1 3.27Å; I56-Y203 WeakPolarHBondContact O-CE1 3.34Å; I56-Y203 PolarHBondContact O-OH 2.74Å; L199-Y203 HydrophobicContact CD1-CE2 4.07Å; L199-Y203 HydrophobicContact CD2-CD2 3.66Å; L199-Y203 HydrophobicContact CD2-CE2 3.86Å; L199-Y203 HydrophobicContact CG-CD2 3.74Å; L199-Y203 HydrophobicContact CG-CE2 3.68Å; L199-Y203 VanDerWaalsContact O-CD2 3.26Å; L199-Y203 WeakPolarHBondContact O-CD2 3.48Å; L199-Y203 PolarHBondContact O-N 3.42Å; T200-Y203 PolarHBondContact O-N 3.48Å; Y203-G207 PolarHBondContact O-N 2.88Å
204V95.2Very high89.9Confident70 Ų7043.1 Ų43.142%0.42423%0.228SC..Hα-helixtrans-62.5-46.2169.5172.40000110.1T200 L201 G207 L208 V232T200-V204 VanDerWaalsContact O-CG2 3.32Å; T200-V204 WeakPolarHBondContact O-CG2 3.47Å; T200-V204 PolarHBondContact O-N 3.15Å; L201-V204 PolarHBondContact O-N 3.03Å; V204-G207 PolarHBondContact O-N 2.86Å; V204-L208 HydrophobicContact CG1-CD1 3.93Å; V204-L208 HydrophobicContact CG1-CG 4.48Å; V204-L208 VanDerWaalsContact O-CG 3.24Å; V204-L208 WeakPolarHBondContact O-CG 3.45Å; V204-L208 PolarHBondContact O-N 3.41Å; V204-V232 HydrophobicContact CB-CG1 4.36Å; V204-V232 HydrophobicContact CG1-CG1 4.14Å; V204-V232 HydrophobicContact CG1-CG2 4.11Å
205F94.7Very high89.9Confident43 Ų4340.3 Ų40.319%0.18922%0.217CC..Hα-helixtrans-57.6-50.3176.3164.2-111.4000112.5L201 F202 L208 I209 A229 V232 A233L201-F205 WeakPolarHBondContact O-CB 3.18Å; L201-F205 PolarHBondContact O-N 2.92Å; F202-F205 WeakPolarHBondContact O-CB 3.39Å; F202-F205 PolarHBondContact O-N 3.3Å; F205-L208 PolarHBondContact O-N 3.09Å; F205-I209 HydrophobicContact CD2-CD1 4.09Å; F205-I209 HydrophobicContact CD2-CG1 4.4Å; F205-I209 HydrophobicContact CE1-CD1 3.81Å; F205-I209 HydrophobicContact CE2-CD1 3.34Å; F205-I209 HydrophobicContact CE2-CG1 4.01Å; F205-I209 HydrophobicContact CZ-CD1 3.18Å; F205-I209 HydrophobicContact CZ-CG1 4.29Å; F205-I209 PolarHBondContact O-N 3.21Å; F205-A229 HydrophobicContact CD2-CB 3.98Å; F205-A229 VanDerWaalsContact CD2-O 3.28Å; F205-A229 WeakPolarHBondContact CD2-O 3.15Å; F205-A229 HydrophobicContact CE2-CB 4.19Å; F205-V232 HydrophobicContact CB-CB 4.5Å; F205-V232 HydrophobicContact CB-CG1 3.9Å; F205-A233 HydrophobicContact CD2-CB 3.84Å; F205-A233 HydrophobicContact CE2-CB 3.71Å; F205-A233 HydrophobicContact CZ-CB 4.37Å
206I91.5Very high89.2Confident3 Ų347.9 Ų47.92%0.01525%0.252CS..Hα-helixtrans-65.2-40.3178.7-67.4-59.4000111.7V55 F202 L208 I209 M210 L388 L392V55-I206 HydrophobicContact CG1-CG2 3.49Å; V55-I206 VanDerWaalsContact CG1-CG2 3.49Å; F202-I206 HydrophobicContact CD1-CG1 3.91Å; F202-I206 HydrophobicContact CE1-CD1 4.12Å; F202-I206 HydrophobicContact CE1-CG1 3.45Å; F202-I206 VanDerWaalsContact CE1-CG1 3.45Å; F202-I206 HydrophobicContact CZ-CD1 4.17Å; F202-I206 HydrophobicContact CZ-CG1 3.98Å; F202-I206 WeakPolarHBondContact O-CG1 3.23Å; F202-I206 PolarHBondContact O-N 2.93Å; I206-L208 VanDerWaalsContact C-N 3.3Å; I206-L208 PolarHBondContact O-N 3.4Å; I206-I209 PolarHBondContact O-N 3.4Å; I206-M210 HydrophobicContact CG2-CG 4.18Å; I206-M210 WeakPolarHBondContact O-CB 3.47Å; I206-M210 VanDerWaalsContact O-CG 3.28Å; I206-M210 WeakPolarHBondContact O-CG 3.3Å; I206-M210 PolarHBondContact O-N 3.21Å; I206-L388 HydrophobicContact CD1-CD1 4.5Å; I206-L388 HydrophobicContact CD1-CD2 3.85Å; I206-L388 HydrophobicContact CG1-CD2 4.47Å; I206-L392 HydrophobicContact CD1-CD1 3.97Å
207G91.3Very high88.5Confident40 Ų4051.6 Ų51.641%0.41226%0.263SS..Hα-helixtrans-59.9-40.7175.400000112.3Y203 V204 M210 F211Y203-G207 PolarHBondContact O-N 2.88Å; V204-G207 PolarHBondContact O-N 2.86Å; G207-M210 PolarHBondContact O-N 2.97Å; G207-F211 VanDerWaalsContact O-CB 3.27Å; G207-F211 WeakPolarHBondContact O-CB 3.16Å; G207-F211 PolarHBondContact O-N 2.9Å
208L93Very high88Confident25 Ų2550.1 Ų50.113%0.13126%0.261CS..Hα-helixtrans-67.6-42.5176.1-70.4166.2000112.6V204 F205 I206 F211 A212 L228 A229 V232V204-L208 HydrophobicContact CG1-CD1 3.93Å; V204-L208 HydrophobicContact CG1-CG 4.48Å; V204-L208 VanDerWaalsContact O-CG 3.24Å; V204-L208 WeakPolarHBondContact O-CG 3.45Å; V204-L208 PolarHBondContact O-N 3.41Å; F205-L208 PolarHBondContact O-N 3.09Å; I206-L208 VanDerWaalsContact C-N 3.3Å; I206-L208 PolarHBondContact O-N 3.4Å; L208-F211 PolarHBondContact O-N 3.44Å; L208-A212 WeakPolarHBondContact O-CB 3.41Å; L208-A212 PolarHBondContact O-N 3Å; L208-L228 HydrophobicContact CD1-CB 4.11Å; L208-L228 HydrophobicContact CD1-CD2 3.99Å; L208-L228 HydrophobicContact CD1-CG 3.65Å; L208-L228 HydrophobicContact CD2-CB 4.38Å; L208-L228 HydrophobicContact CD2-CD2 3.71Å; L208-L228 HydrophobicContact CD2-CG 4.19Å; L208-A229 HydrophobicContact CB-CB 3.84Å; L208-V232 HydrophobicContact CD1-CB 4.48Å; L208-V232 HydrophobicContact CD1-CG2 3.91Å
209I90.9Very high87.6Confident25 Ų2557.2 Ų57.213%0.12830%0.298CS..Hα-helixtrans-61-49.5173.9-74.5-175000110.4F205 I206 F211 A212 L213 A229 L392F205-I209 HydrophobicContact CD2-CD1 4.09Å; F205-I209 HydrophobicContact CD2-CG1 4.4Å; F205-I209 HydrophobicContact CE1-CD1 3.81Å; F205-I209 HydrophobicContact CE2-CD1 3.34Å; F205-I209 HydrophobicContact CE2-CG1 4.01Å; F205-I209 HydrophobicContact CZ-CD1 3.18Å; F205-I209 HydrophobicContact CZ-CG1 4.29Å; F205-I209 PolarHBondContact O-N 3.21Å; I206-I209 PolarHBondContact O-N 3.4Å; I209-F211 VanDerWaalsContact C-N 3.35Å; I209-F211 PolarHBondContact O-N 3.18Å; I209-A212 PolarHBondContact O-N 3.13Å; I209-L213 HydrophobicContact CG2-CD1 3.54Å; I209-L213 HydrophobicContact CG2-CG 4.33Å; I209-L213 WeakPolarHBondContact O-CB 3.38Å; I209-L213 WeakPolarHBondContact O-CG 3.34Å; I209-L213 PolarHBondContact O-N 2.87Å; I209-A229 HydrophobicContact CG1-CB 3.9Å; I209-L392 HydrophobicContact CG2-CD2 4.38Å
210M87Confident87.4Confident11 Ų1161.5 Ų61.55%0.05432%0.32CS..Hα-helixtrans-62.8-42.3-179.7-71.4-78.687.200111.5V55 I206 G207 A212 L213 L214 L392V55-M210 HydrophobicContact CB-SD 4.21Å; V55-M210 HydrophobicContact CG1-CG 4.15Å; V55-M210 HydrophobicContact CG1-SD 3.91Å; V55-M210 HydrophobicContact CG2-SD 4.1Å; I206-M210 HydrophobicContact CG2-CG 4.18Å; I206-M210 WeakPolarHBondContact O-CB 3.47Å; I206-M210 VanDerWaalsContact O-CG 3.28Å; I206-M210 WeakPolarHBondContact O-CG 3.3Å; I206-M210 PolarHBondContact O-N 3.21Å; G207-M210 PolarHBondContact O-N 2.97Å; M210-A212 PolarHBondContact O-N 3.33Å; M210-L213 HydrophobicContact CE-CD1 3.58Å; M210-L213 PolarHBondContact O-N 3.49Å; M210-L214 HydrophobicContact CB-CD1 4.31Å; M210-L214 VanDerWaalsContact O-CB 3.24Å; M210-L214 WeakPolarHBondContact O-CB 3.13Å; M210-L214 WeakPolarHBondContact O-CG 3.27Å; M210-L214 PolarHBondContact O-N 3.35Å; M210-L214 HydrophobicContact SD-CD1 4.42Å; M210-L392 HydrophobicContact CE-CD2 3.52Å; M210-L392 HydrophobicContact SD-CD2 4.36Å
211F87.7Confident87.3Confident91 Ų9161 Ų6140%0.39931%0.314SS..Hα-helixtrans-59.1-47.9174.2178.8-88000111.2G207 L208 I209 L213 L214 N215 L221 S225G207-F211 VanDerWaalsContact O-CB 3.27Å; G207-F211 WeakPolarHBondContact O-CB 3.16Å; G207-F211 PolarHBondContact O-N 2.9Å; L208-F211 PolarHBondContact O-N 3.44Å; I209-F211 VanDerWaalsContact C-N 3.35Å; I209-F211 PolarHBondContact O-N 3.18Å; F211-L213 PolarHBondContact O-N 3.22Å; F211-L214 PolarHBondContact O-N 3.03Å; F211-N215 HydrophobicContact CD1-CB 4.47Å; F211-N215 HydrophobicContact CE1-CB 4.24Å; F211-N215 HydrophobicContact CE2-CB 4.44Å; F211-N215 HydrophobicContact CZ-CB 4.22Å; F211-N215 WeakPolarHBondContact O-CB 3.43Å; F211-N215 PolarHBondContact O-N 3.48Å; F211-L221 HydrophobicContact CE1-CB 4.14Å; F211-S225 WeakPolarHBondContact CD1-OG 3.45Å; F211-S225 WeakPolarHBondContact CE1-OG 3.4Å
212A87.4Confident87Confident4 Ų460.8 Ų60.83%0.03331%0.313CS..Hα-helixtrans-63.4-31.4-179.500000113.2L208 I209 M210 N222 F226L208-A212 WeakPolarHBondContact O-CB 3.41Å; L208-A212 PolarHBondContact O-N 3Å; I209-A212 PolarHBondContact O-N 3.13Å; M210-A212 PolarHBondContact O-N 3.33Å; A212-N222 HydrophobicContact CB-CB 4.48Å; A212-N222 WeakPolarHBondContact CB-O 3.44Å; A212-N222 WeakPolarHBondContact O-CB 3.29Å; A212-N222 VanDerWaalsContact O-CG 3.27Å; A212-N222 PolarHBondContact O-ND2 3.15Å; A212-F226 HydrophobicContact CB-CD1 4.17Å; A212-F226 HydrophobicContact CB-CD2 3.56Å; A212-F226 HydrophobicContact CB-CE1 4.1Å; A212-F226 HydrophobicContact CB-CE2 3.47Å; A212-F226 VanDerWaalsContact CB-CE2 3.47Å; A212-F226 HydrophobicContact CB-CG 3.9Å; A212-F226 HydrophobicContact CB-CZ 3.75Å
213L81.9Confident86.8Confident27 Ų2766.4 Ų66.414%0.14134%0.338CS..Hα-helixtrans-82.6-32.8179.8-70.6169.7000113.8I209 M210 F211 F226 I396I209-L213 HydrophobicContact CG2-CD1 3.54Å; I209-L213 HydrophobicContact CG2-CG 4.33Å; I209-L213 WeakPolarHBondContact O-CB 3.38Å; I209-L213 WeakPolarHBondContact O-CG 3.34Å; I209-L213 PolarHBondContact O-N 2.87Å; M210-L213 HydrophobicContact CE-CD1 3.58Å; M210-L213 PolarHBondContact O-N 3.49Å; F211-L213 PolarHBondContact O-N 3.22Å; L213-F226 HydrophobicContact CD2-CZ 3.81Å; L213-F226 HydrophobicContact CG-CZ 4.09Å; L213-I396 HydrophobicContact CD1-CD1 3.99Å; L213-I396 HydrophobicContact CD1-CG1 3.35Å; L213-I396 HydrophobicContact CD2-CB 4.44Å; L213-I396 HydrophobicContact CD2-CG1 3.69Å; L213-I396 HydrophobicContact CD2-CG2 4.41Å; L213-I396 HydrophobicContact CG-CG1 4.16Å
214L79Confident86.8Confident49 Ų4968.2 Ų68.226%0.25735%0.35SS..Hα-helixtrans-101.3-20.4-171.6-62.2170.7000113T48 I52 M210 F211 Q216T48-L214 HydrophobicContact CG2-CD1 3.63Å; T48-L214 HydrophobicContact CG2-CD2 3.9Å; T48-L214 HydrophobicContact CG2-CG 4.24Å; I52-L214 HydrophobicContact CD1-CD1 3.67Å; I52-L214 HydrophobicContact CG1-CD1 3.64Å; M210-L214 HydrophobicContact CB-CD1 4.31Å; M210-L214 VanDerWaalsContact O-CB 3.24Å; M210-L214 WeakPolarHBondContact O-CB 3.13Å; M210-L214 WeakPolarHBondContact O-CG 3.27Å; M210-L214 PolarHBondContact O-N 3.35Å; M210-L214 HydrophobicContact SD-CD1 4.42Å; F211-L214 PolarHBondContact O-N 3.03Å; L214-Q216 PolarHBondContact O-N 2.85Å
215N81.5Confident86.7Confident27 Ų2765.6 Ų65.614%0.14434%0.335CS..  trans-70.1119.6176.8176.352.3000110.7F211 Q217 L218 N222F211-N215 HydrophobicContact CD1-CB 4.47Å; F211-N215 HydrophobicContact CE1-CB 4.24Å; F211-N215 HydrophobicContact CE2-CB 4.44Å; F211-N215 HydrophobicContact CZ-CB 4.22Å; F211-N215 WeakPolarHBondContact O-CB 3.43Å; F211-N215 PolarHBondContact O-N 3.48Å; N215-Q217 PolarHBondContact OD1-N 3.25Å; N215-L218 PolarHBondContact ND2-O 3.28Å; N215-N222 VanDerWaalsContact CB-OD1 3.24Å; N215-N222 WeakPolarHBondContact CB-OD1 3.49Å; N215-N222 PolarHBondContact ND2-OD1 2.82Å; N215-N222 PolarHBondContact O-ND2 3.38Å; N215-N222 PolarHBondContact O-OD1 2.97Å
216Q72.5Confident86.5Confident176 Ų17667.4 Ų67.482%0.82234%0.343SS*.  trans-98.8-7.2-178.1-64.9-178.3-15.900113.2L214L214-Q216 PolarHBondContact O-N 2.85Å
217Q74.1Confident86.6Confident168 Ų16871 Ų7179%0.78536%0.361SS*.SBendtrans-87.7-45.2-166.7-67.5-178.6-12.100114.2N215N215-Q217 PolarHBondContact OD1-N 3.25Å
218L80.8Confident86.8Confident95 Ų9573.2 Ų73.250%0.49736%0.363SS..  trans-140108.5-168.2-77.7158.1000110.8N215 L220 L221 N222N215-L218 PolarHBondContact ND2-O 3.28Å; L218-L220 PolarHBondContact O-N 3.43Å; L218-L221 HydrophobicContact CB-CB 4.18Å; L218-L221 HydrophobicContact CB-CD1 3.91Å; L218-L221 HydrophobicContact CB-CG 3.86Å; L218-L221 HydrophobicContact CD1-CD1 3.67Å; L218-L221 HydrophobicContact CD1-CG 4.2Å; L218-L221 HydrophobicContact CG-CD1 4.45Å; L218-L221 WeakPolarHBondContact O-CB 3.31Å; L218-L221 PolarHBondContact O-N 3.07Å; L218-N222 PolarHBondContact O-N 3.15Å; L218-N222 PolarHBondContact O-OD1 3.46Å
219L83.9Confident86.9Confident148 Ų14872.1 Ų72.178%0.77536%0.358SS*.Hα-helixtrans-59.9-33.5-180-170.5134.8000112.6L221 N222 F223L219-L221 VanDerWaalsContact C-N 3.34Å; L219-L221 PolarHBondContact O-N 3.03Å; L219-N222 WeakPolarHBondContact O-CB 3.49Å; L219-N222 PolarHBondContact O-N 3.32Å; L219-F223 PolarHBondContact O-N 3.27Å
220L88.3Confident87Confident118 Ų11876 Ų7662%0.61838%0.378SS*.Hα-helixtrans-60.2-42.9174.5-178.965.4000111.9L218 N222 F223 L224L218-L220 PolarHBondContact O-N 3.43Å; L220-N222 VanDerWaalsContact C-N 3.32Å; L220-N222 PolarHBondContact O-N 2.79Å; L220-F223 PolarHBondContact O-N 2.9Å; L220-L224 HydrophobicContact CD1-CD1 4.41Å; L220-L224 HydrophobicContact CD1-CG 4.45Å; L220-L224 HydrophobicContact CG-CD1 4.06Å; L220-L224 WeakPolarHBondContact O-CB 3.48Å; L220-L224 VanDerWaalsContact O-CG 3.3Å; L220-L224 WeakPolarHBondContact O-CG 3.24Å; L220-L224 PolarHBondContact O-N 3.33Å
221L90.8Very high87.4Confident69 Ų6979 Ų7936%0.36140%0.397SS..Hα-helixtrans-65.5-39177.7-66.5-177.7000110.9F211 L218 L219 F223 L224 S225F211-L221 HydrophobicContact CE1-CB 4.14Å; L218-L221 HydrophobicContact CB-CB 4.18Å; L218-L221 HydrophobicContact CB-CD1 3.91Å; L218-L221 HydrophobicContact CB-CG 3.86Å; L218-L221 HydrophobicContact CD1-CD1 3.67Å; L218-L221 HydrophobicContact CD1-CG 4.2Å; L218-L221 HydrophobicContact CG-CD1 4.45Å; L218-L221 WeakPolarHBondContact O-CB 3.31Å; L218-L221 PolarHBondContact O-N 3.07Å; L219-L221 VanDerWaalsContact C-N 3.34Å; L219-L221 PolarHBondContact O-N 3.03Å; L221-F223 VanDerWaalsContact C-N 3.34Å; L221-F223 PolarHBondContact O-N 3.49Å; L221-L224 PolarHBondContact O-N 3.35Å; L221-S225 WeakPolarHBondContact O-CB 3.43Å; L221-S225 PolarHBondContact O-N 2.87Å; L221-S225 PolarHBondContact O-OG 2.9Å
222N87.9Confident87.8Confident30 Ų3075.4 Ų75.416%0.1638%0.382CS..Hα-helixtrans-61.4-46176.9-61.60.3000110.7A212 N215 L218 L219 L220 S225 F226A212-N222 HydrophobicContact CB-CB 4.48Å; A212-N222 WeakPolarHBondContact CB-O 3.44Å; A212-N222 WeakPolarHBondContact O-CB 3.29Å; A212-N222 VanDerWaalsContact O-CG 3.27Å; A212-N222 PolarHBondContact O-ND2 3.15Å; N215-N222 VanDerWaalsContact CB-OD1 3.24Å; N215-N222 WeakPolarHBondContact CB-OD1 3.49Å; N215-N222 PolarHBondContact ND2-OD1 2.82Å; N215-N222 PolarHBondContact O-ND2 3.38Å; N215-N222 PolarHBondContact O-OD1 2.97Å; L218-N222 PolarHBondContact O-N 3.15Å; L218-N222 PolarHBondContact O-OD1 3.46Å; L219-N222 WeakPolarHBondContact O-CB 3.49Å; L219-N222 PolarHBondContact O-N 3.32Å; L220-N222 VanDerWaalsContact C-N 3.32Å; L220-N222 PolarHBondContact O-N 2.79Å; N222-S225 PolarHBondContact O-N 3.31Å; N222-F226 WeakPolarHBondContact O-CD2 3.48Å; N222-F226 PolarHBondContact O-N 3.01Å
223F89.7Confident88Confident123 Ų12376.7 Ų76.754%0.53939%0.393SS..Hα-helixtrans-63.8-45.2178.4-172-106.2000112.4L219 L220 L221 S225 F226 I227L219-F223 PolarHBondContact O-N 3.27Å; L220-F223 PolarHBondContact O-N 2.9Å; L221-F223 VanDerWaalsContact C-N 3.34Å; L221-F223 PolarHBondContact O-N 3.49Å; F223-S225 VanDerWaalsContact C-N 3.33Å; F223-S225 PolarHBondContact O-N 3.38Å; F223-F226 PolarHBondContact O-N 3.31Å; F223-I227 HydrophobicContact CD1-CD1 3.69Å; F223-I227 HydrophobicContact CD1-CG1 4.47Å; F223-I227 HydrophobicContact CE1-CD1 3.28Å; F223-I227 HydrophobicContact CE1-CG1 4.21Å; F223-I227 HydrophobicContact CZ-CD1 3.82Å; F223-I227 HydrophobicContact CZ-CG1 4.4Å; F223-I227 WeakPolarHBondContact O-CG1 3.3Å; F223-I227 PolarHBondContact O-N 3.24Å
224L93.1Very high88.6Confident90 Ų9080.4 Ų80.447%0.47141%0.411SS..Hα-helixtrans-61-41.6175.2-72.5171.7000111.8L220 L221 I227 L228L220-L224 HydrophobicContact CD1-CD1 4.41Å; L220-L224 HydrophobicContact CD1-CG 4.45Å; L220-L224 HydrophobicContact CG-CD1 4.06Å; L220-L224 WeakPolarHBondContact O-CB 3.48Å; L220-L224 VanDerWaalsContact O-CG 3.3Å; L220-L224 WeakPolarHBondContact O-CG 3.24Å; L220-L224 PolarHBondContact O-N 3.33Å; L221-L224 PolarHBondContact O-N 3.35Å; L224-I227 PolarHBondContact O-N 3.09Å; L224-L228 WeakPolarHBondContact O-CB 3.3Å; L224-L228 PolarHBondContact O-N 3.42Å
225S92.7Very high89.3Confident15 Ų1580.8 Ų80.811%0.10542%0.417CS..Hα-helixtrans-65.6-37.4175.7-73.20000112.6F211 L221 N222 F223 L228 A229F211-S225 WeakPolarHBondContact CD1-OG 3.45Å; F211-S225 WeakPolarHBondContact CE1-OG 3.4Å; L221-S225 WeakPolarHBondContact O-CB 3.43Å; L221-S225 PolarHBondContact O-N 2.87Å; L221-S225 PolarHBondContact O-OG 2.9Å; N222-S225 PolarHBondContact O-N 3.31Å; F223-S225 VanDerWaalsContact C-N 3.33Å; F223-S225 PolarHBondContact O-N 3.38Å; S225-L228 PolarHBondContact O-N 3.18Å; S225-A229 VanDerWaalsContact O-CB 3.31Å; S225-A229 WeakPolarHBondContact O-CB 3.42Å; S225-A229 PolarHBondContact O-N 2.91Å
226F91.6Very high89.8Confident82 Ų8279.8 Ų79.836%0.3641%0.411SS..Hα-helixtrans-64.2-44.9171.9-84.8-61.5000112.4A212 L213 N222 F223 L228 A229 I230A212-F226 HydrophobicContact CB-CD1 4.17Å; A212-F226 HydrophobicContact CB-CD2 3.56Å; A212-F226 HydrophobicContact CB-CE1 4.1Å; A212-F226 HydrophobicContact CB-CE2 3.47Å; A212-F226 VanDerWaalsContact CB-CE2 3.47Å; A212-F226 HydrophobicContact CB-CG 3.9Å; A212-F226 HydrophobicContact CB-CZ 3.75Å; L213-F226 HydrophobicContact CD2-CZ 3.81Å; L213-F226 HydrophobicContact CG-CZ 4.09Å; N222-F226 WeakPolarHBondContact O-CD2 3.48Å; N222-F226 PolarHBondContact O-N 3.01Å; F223-F226 PolarHBondContact O-N 3.31Å; F226-L228 VanDerWaalsContact C-N 3.32Å; F226-L228 PolarHBondContact O-N 3.28Å; F226-A229 WeakPolarHBondContact O-CB 3.25Å; F226-A229 PolarHBondContact O-N 3.44Å; F226-I230 WeakPolarHBondContact O-CG1 3.32Å; F226-I230 PolarHBondContact O-N 2.95Å
227I93.6Very high90.8Very high77 Ų7775.7 Ų75.740%0.39539%0.391SS..Hα-helixtrans-59.2-47.5175.4-70.4173000110.1F223 L224 A229 I230 V231F223-I227 HydrophobicContact CD1-CD1 3.69Å; F223-I227 HydrophobicContact CD1-CG1 4.47Å; F223-I227 HydrophobicContact CE1-CD1 3.28Å; F223-I227 HydrophobicContact CE1-CG1 4.21Å; F223-I227 HydrophobicContact CZ-CD1 3.82Å; F223-I227 HydrophobicContact CZ-CG1 4.4Å; F223-I227 WeakPolarHBondContact O-CG1 3.3Å; F223-I227 PolarHBondContact O-N 3.24Å; L224-I227 PolarHBondContact O-N 3.09Å; I227-A229 VanDerWaalsContact C-N 3.31Å; I227-A229 PolarHBondContact O-N 3.38Å; I227-I230 WeakPolarHBondContact O-CB 3.02Å; I227-I230 PolarHBondContact O-N 2.84Å; I227-I230 VanDerWaalsContact O-N 3.16Å; I227-V231 WeakPolarHBondContact O-CG2 3.32Å; I227-V231 PolarHBondContact O-N 3.24Å
228L95.8Very high91.6Very high87 Ų8774.7 Ų74.746%0.45538%0.384SS..Hα-helixtrans-63.7-38.3179.2-171.658.9000111.4L208 L224 S225 F226 I230 V231 V232L208-L228 HydrophobicContact CD1-CB 4.11Å; L208-L228 HydrophobicContact CD1-CD2 3.99Å; L208-L228 HydrophobicContact CD1-CG 3.65Å; L208-L228 HydrophobicContact CD2-CB 4.38Å; L208-L228 HydrophobicContact CD2-CD2 3.71Å; L208-L228 HydrophobicContact CD2-CG 4.19Å; L224-L228 WeakPolarHBondContact O-CB 3.3Å; L224-L228 PolarHBondContact O-N 3.42Å; S225-L228 PolarHBondContact O-N 3.18Å; F226-L228 VanDerWaalsContact C-N 3.32Å; F226-L228 PolarHBondContact O-N 3.28Å; L228-I230 VanDerWaalsContact C-N 3.33Å; L228-I230 PolarHBondContact O-N 2.72Å; L228-V231 PolarHBondContact O-N 3.36Å; L228-V232 HydrophobicContact CG-CG2 4.49Å; L228-V232 VanDerWaalsContact O-CG2 3.3Å; L228-V232 WeakPolarHBondContact O-CG2 3.28Å; L228-V232 PolarHBondContact O-N 3.47Å
229A94.9Very high92.1Very high2 Ų271.2 Ų71.22%0.01737%0.367CS..Hα-helixtrans-59.7-42.7173.800000111.5F205 L208 I209 S225 F226 I227 V231 V232 A233F205-A229 HydrophobicContact CD2-CB 3.98Å; F205-A229 VanDerWaalsContact CD2-O 3.28Å; F205-A229 WeakPolarHBondContact CD2-O 3.15Å; F205-A229 HydrophobicContact CE2-CB 4.19Å; L208-A229 HydrophobicContact CB-CB 3.84Å; I209-A229 HydrophobicContact CG1-CB 3.9Å; S225-A229 VanDerWaalsContact O-CB 3.31Å; S225-A229 WeakPolarHBondContact O-CB 3.42Å; S225-A229 PolarHBondContact O-N 2.91Å; F226-A229 WeakPolarHBondContact O-CB 3.25Å; F226-A229 PolarHBondContact O-N 3.44Å; I227-A229 VanDerWaalsContact C-N 3.31Å; I227-A229 PolarHBondContact O-N 3.38Å; A229-V231 PolarHBondContact O-N 3.19Å; A229-V232 PolarHBondContact O-N 3.39Å; A229-A233 VanDerWaalsContact O-CB 3.31Å; A229-A233 WeakPolarHBondContact O-CB 3Å; A229-A233 PolarHBondContact O-N 2.93Å
230I93.9Very high92.5Very high106 Ų10664.3 Ų64.354%0.54433%0.331SS..Hα-helixtrans-62.3-44.3175.7-65.7165.3000110.7F226 I227 L228 V232 A233 M234F226-I230 WeakPolarHBondContact O-CG1 3.32Å; F226-I230 PolarHBondContact O-N 2.95Å; I227-I230 WeakPolarHBondContact O-CB 3.02Å; I227-I230 PolarHBondContact O-N 2.84Å; I227-I230 VanDerWaalsContact O-N 3.16Å; L228-I230 VanDerWaalsContact C-N 3.33Å; L228-I230 PolarHBondContact O-N 2.72Å; I230-V232 PolarHBondContact O-N 2.86Å; I230-A233 PolarHBondContact O-N 3.47Å; I230-M234 HydrophobicContact CG2-CE 4.25Å; I230-M234 WeakPolarHBondContact O-CG 3.37Å; I230-M234 PolarHBondContact O-N 2.96Å
231V94.9Very high92.6Very high74 Ų7464 Ų6445%0.44832%0.324SS..Hα-helixtrans-60.8-45.7176.9174.60000111.4I227 L228 A229 M234 C235I227-V231 WeakPolarHBondContact O-CG2 3.32Å; I227-V231 PolarHBondContact O-N 3.24Å; L228-V231 PolarHBondContact O-N 3.36Å; A229-V231 PolarHBondContact O-N 3.19Å; V231-M234 HydrophobicContact CB-CE 4.5Å; V231-M234 HydrophobicContact CG2-CE 4.22Å; V231-M234 PolarHBondContact O-N 3.3Å; V231-C235 PolarHBondContact O-N 2.83Å
232V95.2Very high92.4Very high17 Ų1768.7 Ų68.710%0.10334%0.344CS..Hα-helixtrans-66.1-39.7177.7176.60000111L201 V204 F205 L208 L228 A229 I230 M234 C235 L236L201-V232 HydrophobicContact CD2-CG1 4.38Å; L201-V232 WeakPolarHBondContact O-CG1 3.46Å; V204-V232 HydrophobicContact CB-CG1 4.36Å; V204-V232 HydrophobicContact CG1-CG1 4.14Å; V204-V232 HydrophobicContact CG1-CG2 4.11Å; F205-V232 HydrophobicContact CB-CB 4.5Å; F205-V232 HydrophobicContact CB-CG1 3.9Å; L208-V232 HydrophobicContact CD1-CB 4.48Å; L208-V232 HydrophobicContact CD1-CG2 3.91Å; L228-V232 HydrophobicContact CG-CG2 4.49Å; L228-V232 VanDerWaalsContact O-CG2 3.3Å; L228-V232 WeakPolarHBondContact O-CG2 3.28Å; L228-V232 PolarHBondContact O-N 3.47Å; A229-V232 PolarHBondContact O-N 3.39Å; I230-V232 PolarHBondContact O-N 2.86Å; V232-M234 PolarHBondContact O-N 3.24Å; V232-C235 WeakPolarHBondContact O-CB 3.49Å; V232-C235 PolarHBondContact O-N 2.87Å; V232-L236 WeakPolarHBondContact O-CB 3.48Å; V232-L236 PolarHBondContact O-N 3.2Å
233A93.1Very high92.3Very high31 Ų3169.5 Ų69.526%0.25635%0.35SS..Hα-helixtrans-62-41.2175.300000112.1F205 A229 I230 C235 L236 F237F205-A233 HydrophobicContact CD2-CB 3.84Å; F205-A233 HydrophobicContact CE2-CB 3.71Å; F205-A233 HydrophobicContact CZ-CB 4.37Å; A229-A233 VanDerWaalsContact O-CB 3.31Å; A229-A233 WeakPolarHBondContact O-CB 3Å; A229-A233 PolarHBondContact O-N 2.93Å; I230-A233 PolarHBondContact O-N 3.47Å; A233-C235 VanDerWaalsContact C-N 3.34Å; A233-L236 PolarHBondContact O-N 3.15Å; A233-F237 WeakPolarHBondContact O-CB 3.36Å; A233-F237 PolarHBondContact O-N 3.24Å
234M93.4Very high92Very high105 Ų10569.2 Ų69.252%0.51736%0.363SS..Hα-helixtrans-63.9-39.8173.7-70.9-171.7-66.200112I230 V231 V232 K238I230-M234 HydrophobicContact CG2-CE 4.25Å; I230-M234 WeakPolarHBondContact O-CG 3.37Å; I230-M234 PolarHBondContact O-N 2.96Å; V231-M234 HydrophobicContact CB-CE 4.5Å; V231-M234 HydrophobicContact CG2-CE 4.22Å; V231-M234 PolarHBondContact O-N 3.3Å; V232-M234 PolarHBondContact O-N 3.24Å; M234-K238 WeakPolarHBondContact O-CG 3.46Å; M234-K238 PolarHBondContact O-N 3.01Å; M234-K238 VanDerWaalsContact O-N 3.1Å
235C93.1Very high91.6Very high56 Ų5666.4 Ų66.438%0.37835%0.351SS..Hα-helixtrans-64.2-48.8175.2-173.30000111.3V231 V232 A233 F237 K238 V239V231-C235 PolarHBondContact O-N 2.83Å; V232-C235 WeakPolarHBondContact O-CB 3.49Å; V232-C235 PolarHBondContact O-N 2.87Å; A233-C235 VanDerWaalsContact C-N 3.34Å; C235-F237 VanDerWaalsContact C-N 3.33Å; C235-F237 PolarHBondContact O-N 3.4Å; C235-K238 PolarHBondContact O-N 3.21Å; C235-K238 VanDerWaalsContact O-N 3.15Å; C235-V239 WeakPolarHBondContact O-CG2 3.31Å; C235-V239 PolarHBondContact O-N 3.45Å
236L93.4Very high91.5Very high6 Ų666.3 Ų66.33%0.03135%0.35CS..Hα-helixtrans-53.8-50.4175.3175.869.6000110.7G198 L201 F202 V232 A233 K238 V239 E240 L248G198-L236 WeakPolarHBondContact O-CD1 3.27Å; L201-L236 HydrophobicContact CB-CB 4.27Å; L201-L236 HydrophobicContact CB-CD1 3.81Å; F202-L236 HydrophobicContact CB-CD1 4.44Å; F202-L236 HydrophobicContact CB-CD2 4.36Å; F202-L236 HydrophobicContact CD2-CD2 3.78Å; V232-L236 WeakPolarHBondContact O-CB 3.48Å; V232-L236 PolarHBondContact O-N 3.2Å; A233-L236 PolarHBondContact O-N 3.15Å; L236-K238 VanDerWaalsContact C-N 3.3Å; L236-K238 PolarHBondContact O-N 2.66Å; L236-V239 PolarHBondContact O-N 2.95Å; L236-V239 VanDerWaalsContact O-N 3.14Å; L236-E240 HydrophobicContact CD1-CG 3.65Å; L236-E240 HydrophobicContact CG-CG 4.08Å; L236-E240 WeakPolarHBondContact O-CB 3.44Å; L236-E240 VanDerWaalsContact O-CG 3.23Å; L236-E240 WeakPolarHBondContact O-CG 3.29Å; L236-E240 PolarHBondContact O-N 3.44Å; L236-L248 HydrophobicContact CD2-CD2 3.84Å
237F92.5Very high91.4Very high91 Ų9162.6 Ų62.640%0.39933%0.334SS..Hα-helixtrans-60-38.6179.2-175.4-106.5000112.9A233 C235 K241 V250A233-F237 WeakPolarHBondContact O-CB 3.36Å; A233-F237 PolarHBondContact O-N 3.24Å; C235-F237 VanDerWaalsContact C-N 3.33Å; C235-F237 PolarHBondContact O-N 3.4Å; F237-K241 HydrophobicContact CD1-CD 4.38Å; F237-K241 HydrophobicContact CE1-CD 4.15Å; F237-K241 HydrophobicContact CZ-CD 4.48Å; F237-K241 VanDerWaalsContact O-CG 3.29Å; F237-K241 WeakPolarHBondContact O-CG 3.27Å; F237-K241 PolarHBondContact O-N 3.43Å; F237-V250 HydrophobicContact CD2-CB 3.79Å; F237-V250 HydrophobicContact CD2-CG1 3.67Å; F237-V250 HydrophobicContact CD2-CG2 4.46Å; F237-V250 HydrophobicContact CE2-CB 3.88Å; F237-V250 HydrophobicContact CE2-CG1 4.26Å
238K92Very high91.3Very high147 Ų14760 Ų6064%0.63932%0.32SS*.Hα-helixtrans-68.3-41.8175-73.8179-179.3-1780112.1M234 C235 L236 H242M234-K238 WeakPolarHBondContact O-CG 3.46Å; M234-K238 PolarHBondContact O-N 3.01Å; M234-K238 VanDerWaalsContact O-N 3.1Å; C235-K238 PolarHBondContact O-N 3.21Å; C235-K238 VanDerWaalsContact O-N 3.15Å; L236-K238 VanDerWaalsContact C-N 3.3Å; L236-K238 PolarHBondContact O-N 2.66Å; K238-H242 PolarHBondContact O-CD2 2.89Å
239V91.6Very high91.1Very high22 Ų2256 Ų5613%0.13330%0.3CS..Hα-helixtrans-65.9-52179.91710000110.5K197 L201 C235 L236 K241 H242 V243K197-V239 HydrophobicContact CD-CG1 3.89Å; K197-V239 HydrophobicContact CG-CG1 4.21Å; L201-V239 HydrophobicContact CD1-CB 4.18Å; L201-V239 HydrophobicContact CD1-CG1 4.39Å; L201-V239 HydrophobicContact CD1-CG2 3.88Å; C235-V239 WeakPolarHBondContact O-CG2 3.31Å; C235-V239 PolarHBondContact O-N 3.45Å; L236-V239 PolarHBondContact O-N 2.95Å; L236-V239 VanDerWaalsContact O-N 3.14Å; V239-K241 PolarHBondContact O-N 3.47Å; V239-H242 PolarHBondContact O-N 3.13Å; V239-V243 HydrophobicContact CG1-CG2 4.27Å; V239-V243 WeakPolarHBondContact O-CG2 3.32Å; V239-V243 PolarHBondContact O-N 3.19Å
240E92Very high91Very high2 Ų256.4 Ų56.41%0.00930%0.302CS..Hα-helixtrans-63.6-27.8-174.2-68.4-78.4-153.300113G198 L236 H242 V243 P246 F247 L248 V250G198-E240 WeakPolarHBondContact CA-OE1 3.38Å; L236-E240 HydrophobicContact CD1-CG 3.65Å; L236-E240 HydrophobicContact CG-CG 4.08Å; L236-E240 WeakPolarHBondContact O-CB 3.44Å; L236-E240 VanDerWaalsContact O-CG 3.23Å; L236-E240 WeakPolarHBondContact O-CG 3.29Å; L236-E240 PolarHBondContact O-N 3.44Å; E240-H242 PolarHBondContact O-N 2.95Å; E240-V243 PolarHBondContact O-N 3.13Å; E240-P246 HydrophobicContact CB-CB 4.21Å; E240-P246 WeakPolarHBondContact OE2-CA 3.49Å; E240-P246 WeakPolarHBondContact OE2-CB 3.34Å; E240-F247 WeakPolarHBondContact OE1-CB 3.47Å; E240-F247 PolarHBondContact OE1-N 2.93Å; E240-F247 PolarHBondContact OE2-N 3.47Å; E240-F247 VanDerWaalsContact OE2-N 3.14Å; E240-L248 HydrophobicContact CG-CB 4.38Å; E240-L248 PolarHBondContact OE1-N 2.96Å; E240-V250 HydrophobicContact CB-CG1 3.89Å; E240-V250 HydrophobicContact CB-CG2 3.87Å
241K89Confident90.8Very high111 Ų11157.2 Ų57.248%0.48331%0.312SS..THydrogen-bonded Turntrans-61.1-25.2173.2-85.5-178.7175.7-174.10114.3F237 V239 V250F237-K241 HydrophobicContact CD1-CD 4.38Å; F237-K241 HydrophobicContact CE1-CD 4.15Å; F237-K241 HydrophobicContact CZ-CD 4.48Å; F237-K241 VanDerWaalsContact O-CG 3.29Å; F237-K241 WeakPolarHBondContact O-CG 3.27Å; F237-K241 PolarHBondContact O-N 3.43Å; V239-K241 PolarHBondContact O-N 3.47Å; K241-V250 HydrophobicContact CG-CG2 3.83Å
242H87.3Confident90.8Very high168 Ų16855.4 Ų55.478%0.77830%0.298SS*.THydrogen-bonded Turntrans-106.9-1.3-175.3-62.1-60.9000112.8K238 V239 E240K238-H242 PolarHBondContact O-CD2 2.89Å; V239-H242 PolarHBondContact O-N 3.13Å; E240-H242 PolarHBondContact O-N 2.95Å
243V86.5Confident90.6Very high47 Ų4757.6 Ų57.629%0.28531%0.307SS..  trans-91.9134.6178.5178.50000109.2D195 V239 E240 S245D195-V243 HydrophobicContact CB-CG1 4.3Å; V239-V243 HydrophobicContact CG1-CG2 4.27Å; V239-V243 WeakPolarHBondContact O-CG2 3.32Å; V239-V243 PolarHBondContact O-N 3.19Å; E240-V243 PolarHBondContact O-N 3.13Å; V243-S245 VanDerWaalsContact C-N 3.32Å; V243-S245 PolarHBondContact O-N 3.01Å
244S82.4Confident90.6Very high117 Ų11759.2 Ų59.282%0.81831%0.311SS*.SBendtrans-72.4-24.1-178.956.40000113.8
245S85.5Confident90.5Very high31 Ų3159.8 Ų59.822%0.21731%0.307CS..SBendtrans-137.374.5175.6-70.70000109.5S192 V243S192-S245 WeakPolarHBondContact CB-OG 3.07Å; S192-S245 WeakPolarHBondContact OG-CB 3.36Å; S192-S245 PolarHBondContact OG-OG 3.34Å; V243-S245 VanDerWaalsContact C-N 3.32Å; V243-S245 PolarHBondContact O-N 3.01Å
246P89.6Confident90.5Very high13 Ų1357.9 Ų57.98%0.08430%0.295CS..  trans-63.1148.5-173.627.2-35.8000111.5E240 L248 K381E240-P246 HydrophobicContact CB-CB 4.21Å; E240-P246 WeakPolarHBondContact OE2-CA 3.49Å; E240-P246 WeakPolarHBondContact OE2-CB 3.34Å; P246-L248 WeakPolarHBondContact CB-O 3.3Å; P246-K381 PolarHBondContact O-NZ 2.82Å
247F90.3Very high90.6Very high4 Ų457.6 Ų57.62%0.01829%0.293CS..SBendtrans-68.2-47.7170.1176.7-103.3000109.7P59 E63 D195 L199 F202 E240 P249 F385P59-F247 HydrophobicContact CB-CE1 4.08Å; P59-F247 HydrophobicContact CB-CZ 3.8Å; E63-F247 HydrophobicContact CB-CD2 4.18Å; E63-F247 HydrophobicContact CB-CE2 3.9Å; E63-F247 HydrophobicContact CG-CD2 4.38Å; E63-F247 HydrophobicContact CG-CE2 4.44Å; D195-F247 HydrophobicContact CB-CB 4.33Å; D195-F247 PolarHBondContact OD2-N 3.42Å; L199-F247 HydrophobicContact CB-CD2 4.27Å; L199-F247 HydrophobicContact CB-CG 4.19Å; L199-F247 HydrophobicContact CD1-CD2 4.13Å; L199-F247 HydrophobicContact CD1-CE2 3.88Å; L199-F247 HydrophobicContact CD1-CZ 4.35Å; L199-F247 HydrophobicContact CG-CE2 4.49Å; F202-F247 HydrophobicContact CB-CD1 4.03Å; F202-F247 HydrophobicContact CB-CE1 4.02Å; F202-F247 AromaticContact CD1-CE1 3.81Å; F202-F247 HydrophobicContact CD1-CE1 3.81Å; F202-F247 HydrophobicContact CD2-CD1 4.39Å; F202-F247 HydrophobicContact CD2-CE1 4.24Å; F202-F247 HydrophobicContact CE1-CE1 4.39Å; F202-F247 HydrophobicContact CG-CD1 4.08Å; F202-F247 AromaticContact CG-CE1 3.74Å; F202-F247 HydrophobicContact CG-CE1 3.74Å; E240-F247 WeakPolarHBondContact OE1-CB 3.47Å; E240-F247 PolarHBondContact OE1-N 2.93Å; E240-F247 PolarHBondContact OE2-N 3.47Å; E240-F247 VanDerWaalsContact OE2-N 3.14Å; F247-P249 WeakPolarHBondContact O-CD 3.47Å; F247-F385 HydrophobicContact CD1-CE1 4.36Å; F247-F385 AromaticContact CD1-CZ 3.95Å; F247-F385 HydrophobicContact CD1-CZ 3.95Å; F247-F385 AromaticContact CE1-CE1 3.86Å; F247-F385 HydrophobicContact CE1-CE1 3.86Å; F247-F385 AromaticContact CE1-CZ 3.78Å; F247-F385 HydrophobicContact CE1-CZ 3.78Å; F247-F385 HydrophobicContact CZ-CE1 4.48Å; F247-F385 HydrophobicContact CZ-CZ 4.33Å; F247-F385 WeakPolarHBondContact O-CE2 3.37Å; F247-F385 VanDerWaalsContact O-CZ 3.3Å; F247-F385 WeakPolarHBondContact O-CZ 3.33Å
248L91.6Very high90.7Very high22 Ų2256 Ų5612%0.11529%0.291CS..SBendtrans-100.6108.5170.6179.564000110.6F202 L236 E240 P246 V250 F253 F385F202-L248 HydrophobicContact CD2-CD2 4.36Å; F202-L248 HydrophobicContact CE2-CD2 4.28Å; L236-L248 HydrophobicContact CD2-CD2 3.84Å; E240-L248 HydrophobicContact CG-CB 4.38Å; E240-L248 PolarHBondContact OE1-N 2.96Å; P246-L248 WeakPolarHBondContact CB-O 3.3Å; L248-V250 HydrophobicContact CD2-CG1 4.06Å; L248-V250 HydrophobicContact CG-CG1 4.02Å; L248-V250 PolarHBondContact O-N 3.48Å; L248-F253 HydrophobicContact CD1-CE2 3.96Å; L248-F253 HydrophobicContact CD1-CZ 4.35Å; L248-F253 HydrophobicContact CG-CE2 4.5Å; L248-F385 HydrophobicContact CB-CE2 4.3Å; L248-F385 HydrophobicContact CB-CZ 3.97Å; L248-F385 HydrophobicContact CD1-CD1 3.83Å; L248-F385 HydrophobicContact CD1-CD2 3.49Å; L248-F385 VanDerWaalsContact CD1-CD2 3.49Å; L248-F385 HydrophobicContact CD1-CE1 3.77Å; L248-F385 HydrophobicContact CD1-CE2 3.47Å; L248-F385 VanDerWaalsContact CD1-CE2 3.47Å; L248-F385 HydrophobicContact CD1-CG 3.7Å; L248-F385 HydrophobicContact CD1-CZ 3.61Å; L248-F385 HydrophobicContact CG-CE2 4.48Å; L248-F385 HydrophobicContact CG-CZ 4.41Å
249P91.4Very high90.9Very high3 Ų349.3 Ų49.32%0.01926%0.262CS..  trans-69.871.4-179.3-19.634.1000113.2F247 V251 E252 Q378 K381 M382F247-P249 WeakPolarHBondContact O-CD 3.47Å; P249-V251 PolarHBondContact O-N 2.94Å; P249-E252 HydrophobicContact CB-CB 4.41Å; P249-E252 HydrophobicContact CB-CG 3.7Å; P249-E252 WeakPolarHBondContact O-CB 3.43Å; P249-E252 PolarHBondContact O-N 3.48Å; P249-Q378 HydrophobicContact CB-CB 4.11Å; P249-Q378 HydrophobicContact CB-CG 3.97Å; P249-Q378 HydrophobicContact CG-CB 4.05Å; P249-Q378 HydrophobicContact CG-CG 4.1Å; P249-K381 HydrophobicContact CG-CB 3.95Å; P249-K381 HydrophobicContact CG-CD 4.02Å; P249-M382 HydrophobicContact CB-SD 4.21Å; P249-M382 HydrophobicContact CG-SD 4.34Å
250V91.5Very high91.1Very high11 Ų1148.2 Ų48.27%0.06726%0.256CS..G310 helixtrans-58-22.9-175.3-660000114.1F237 E240 K241 L248 E252 F253F237-V250 HydrophobicContact CD2-CB 3.79Å; F237-V250 HydrophobicContact CD2-CG1 3.67Å; F237-V250 HydrophobicContact CD2-CG2 4.46Å; F237-V250 HydrophobicContact CE2-CB 3.88Å; F237-V250 HydrophobicContact CE2-CG1 4.26Å; E240-V250 HydrophobicContact CB-CG1 3.89Å; E240-V250 HydrophobicContact CB-CG2 3.87Å; K241-V250 HydrophobicContact CG-CG2 3.83Å; L248-V250 HydrophobicContact CD2-CG1 4.06Å; L248-V250 HydrophobicContact CG-CG1 4.02Å; L248-V250 PolarHBondContact O-N 3.48Å; V250-E252 VanDerWaalsContact C-N 3.29Å; V250-F253 PolarHBondContact O-N 2.83Å
251V91.5Very high91.3Very high124 Ų12449.1 Ų49.175%0.75226%0.26SS*.G310 helixtrans-71.4-24.2177.5-1770000112.2P249 F253P249-V251 PolarHBondContact O-N 2.94Å; V251-F253 VanDerWaalsContact C-N 3.28Å; V251-F253 PolarHBondContact O-N 2.65Å
252E93.3Very high91.7Very high35 Ų3547 Ų4716%0.16425%0.253CS..G310 helixtrans-75.7-16177.8-58.5-70.5160.700112.1P249 V250 N254 I257 T374 S375 Q378 M382P249-E252 HydrophobicContact CB-CB 4.41Å; P249-E252 HydrophobicContact CB-CG 3.7Å; P249-E252 WeakPolarHBondContact O-CB 3.43Å; P249-E252 PolarHBondContact O-N 3.48Å; V250-E252 VanDerWaalsContact C-N 3.29Å; E252-N254 PolarHBondContact O-N 3.13Å; E252-I257 WeakPolarHBondContact O-CD1 3.49Å; E252-T374 HydrophobicContact CB-CG2 4.35Å; E252-T374 HydrophobicContact CG-CG2 3.99Å; E252-T374 WeakPolarHBondContact OE2-CA 3.34Å; E252-T374 WeakPolarHBondContact OE2-CG2 3.49Å; E252-S375 VanDerWaalsContact OE1-CB 3.3Å; E252-S375 WeakPolarHBondContact OE1-CB 3.34Å; E252-S375 PolarHBondContact OE1-OG 2.67Å; E252-S375 PolarHBondContact OE2-N 3.43Å; E252-Q378 HydrophobicContact CG-CB 3.92Å; E252-Q378 HydrophobicContact CG-CG 4.19Å; E252-M382 HydrophobicContact CB-CE 3.99Å; E252-M382 HydrophobicContact CB-CG 4.1Å; E252-M382 HydrophobicContact CB-SD 3.96Å; E252-M382 HydrophobicContact CG-CG 4.24Å; E252-M382 HydrophobicContact CG-SD 4.45Å
253F92.7Very high92.2Very high64 Ų6439 Ų3928%0.28122%0.216SC..  trans-7575.2178.7-75.1-92.7000111.9L248 V250 V251 I257 F261 M382L248-F253 HydrophobicContact CD1-CE2 3.96Å; L248-F253 HydrophobicContact CD1-CZ 4.35Å; L248-F253 HydrophobicContact CG-CE2 4.5Å; V250-F253 PolarHBondContact O-N 2.83Å; V251-F253 VanDerWaalsContact C-N 3.28Å; V251-F253 PolarHBondContact O-N 2.65Å; F253-I257 HydrophobicContact CD1-CG2 4.04Å; F253-I257 HydrophobicContact CE1-CG2 4.37Å; F253-F261 HydrophobicContact CE1-CD1 4.14Å; F253-F261 AromaticContact CE1-CD2 3.81Å; F253-F261 HydrophobicContact CE1-CD2 3.81Å; F253-F261 HydrophobicContact CE1-CE1 4.27Å; F253-F261 AromaticContact CE1-CE2 3.94Å; F253-F261 HydrophobicContact CE1-CE2 3.94Å; F253-F261 AromaticContact CE1-CG 3.91Å; F253-F261 HydrophobicContact CE1-CG 3.91Å; F253-F261 HydrophobicContact CE1-CZ 4.17Å; F253-F261 HydrophobicContact CZ-CE1 4.26Å; F253-F261 HydrophobicContact CZ-CE2 4.27Å; F253-F261 HydrophobicContact CZ-CZ 4.12Å; F253-M382 HydrophobicContact CD2-CE 3.97Å; F253-M382 HydrophobicContact CD2-SD 4.5Å; F253-M382 HydrophobicContact CE1-CE 4.2Å; F253-M382 HydrophobicContact CE2-CE 3.61Å; F253-M382 HydrophobicContact CE2-SD 3.93Å; F253-M382 HydrophobicContact CG-CE 4.44Å; F253-M382 HydrophobicContact CZ-CE 3.74Å; F253-M382 HydrophobicContact CZ-SD 4.4Å
254N91.4Very high92.6Very high65 Ų6536.8 Ų36.835%0.34820%0.203SC..  trans-75.6176.8166.270.746.1000110.8E252 S256 I257 T258E252-N254 PolarHBondContact O-N 3.13Å; N254-S256 VanDerWaalsContact C-N 3.3Å; N254-S256 PolarHBondContact O-N 2.6Å; N254-S256 WeakPolarHBondContact OD1-CA 3.39Å; N254-S256 VanDerWaalsContact OD1-CB 3.3Å; N254-S256 WeakPolarHBondContact OD1-CB 3.24Å; N254-S256 PolarHBondContact OD1-N 3.45Å; N254-I257 PolarHBondContact O-N 3.29Å; N254-I257 PolarHBondContact OD1-N 3.48Å; N254-T258 WeakPolarHBondContact O-CB 3.37Å; N254-T258 PolarHBondContact O-N 3.4Å; N254-T258 PolarHBondContact O-OG1 2.85Å
255R91.3Very high93.2Very high116 Ų11633.7 Ų33.744%0.43818%0.177SC..Hα-helixtrans-59.7-38-177.8-168.5176.3-171.8-172.1-2.1113.3L259 F437R255-L259 WeakPolarHBondContact O-CB 3.38Å; R255-L259 VanDerWaalsContact O-CG 3.29Å; R255-L259 WeakPolarHBondContact O-CG 3.18Å; R255-L259 PolarHBondContact O-N 2.88Å; R255-L259 VanDerWaalsContact O-N 3.15Å; R255-F437 PolarHBondContact NE-O 3.47Å; R255-F437 VanDerWaalsContact NH2-CA 3.32Å; R255-F437 PolarHBondContact NH2-O 3.29Å
256S93Very high93.8Very high16 Ų1634.5 Ų34.511%0.11218%0.178CC..Hα-helixtrans-70.2-51.6-179.8178.60000110.7N254 T258 L259 V260 R320 E373N254-S256 VanDerWaalsContact C-N 3.3Å; N254-S256 PolarHBondContact O-N 2.6Å; N254-S256 WeakPolarHBondContact OD1-CA 3.39Å; N254-S256 VanDerWaalsContact OD1-CB 3.3Å; N254-S256 WeakPolarHBondContact OD1-CB 3.24Å; N254-S256 PolarHBondContact OD1-N 3.45Å; S256-T258 VanDerWaalsContact C-N 3.33Å; S256-T258 PolarHBondContact O-N 2.89Å; S256-L259 PolarHBondContact O-N 3.34Å; S256-V260 WeakPolarHBondContact O-CG2 3.43Å; S256-V260 PolarHBondContact O-N 2.89Å; S256-R320 PolarHBondContact OG-NH1 3.48Å; S256-E373 WeakPolarHBondContact CB-OE2 3.35Å; S256-E373 PolarHBondContact OG-OE2 3.33Å
257I95.4Very high94.1Very high0 Ų033.9 Ų33.90%017%0.174CC..Hα-helixtrans-60-43.9177.3-71.5174.7000110.7E252 F253 N254 L259 V260 F261 E373 M382E252-I257 WeakPolarHBondContact O-CD1 3.49Å; F253-I257 HydrophobicContact CD1-CG2 4.04Å; F253-I257 HydrophobicContact CE1-CG2 4.37Å; N254-I257 PolarHBondContact O-N 3.29Å; N254-I257 PolarHBondContact OD1-N 3.48Å; I257-L259 PolarHBondContact O-N 3.29Å; I257-V260 WeakPolarHBondContact O-CB 3.37Å; I257-V260 PolarHBondContact O-N 3.01Å; I257-F261 HydrophobicContact CG2-CD2 3.73Å; I257-F261 HydrophobicContact CG2-CE2 3.75Å; I257-F261 WeakPolarHBondContact O-CD2 3.3Å; I257-F261 PolarHBondContact O-N 2.98Å; I257-E373 HydrophobicContact CD1-CB 4.19Å; I257-E373 HydrophobicContact CG1-CB 4.38Å; I257-M382 HydrophobicContact CG2-CE 3.77Å
258T95.3Very high94.3Very high57 Ų5733.7 Ų33.735%0.3517%0.173SC..Hα-helixtrans-60.4-44.2177.6-56.10000111.9N254 S256 V260 F261 I262N254-T258 WeakPolarHBondContact O-CB 3.37Å; N254-T258 PolarHBondContact O-N 3.4Å; N254-T258 PolarHBondContact O-OG1 2.85Å; S256-T258 VanDerWaalsContact C-N 3.33Å; S256-T258 PolarHBondContact O-N 2.89Å; T258-V260 VanDerWaalsContact C-N 3.32Å; T258-V260 PolarHBondContact O-N 2.89Å; T258-F261 PolarHBondContact O-N 3.38Å; T258-I262 HydrophobicContact CG2-CD1 4.12Å; T258-I262 WeakPolarHBondContact O-CG1 3.12Å; T258-I262 PolarHBondContact O-N 3.35Å; T258-I262 VanDerWaalsContact O-N 3.11Å
259L95.9Very high94.4Very high7 Ų733.2 Ų33.24%0.03717%0.171CC..Hα-helixtrans-62.8-39.5176.4-78171.7000112.3R255 S256 I257 I262 T263 L433 F437 F438R255-L259 WeakPolarHBondContact O-CB 3.38Å; R255-L259 VanDerWaalsContact O-CG 3.29Å; R255-L259 WeakPolarHBondContact O-CG 3.18Å; R255-L259 PolarHBondContact O-N 2.88Å; R255-L259 VanDerWaalsContact O-N 3.15Å; S256-L259 PolarHBondContact O-N 3.34Å; I257-L259 PolarHBondContact O-N 3.29Å; L259-I262 PolarHBondContact O-N 3.19Å; L259-T263 VanDerWaalsContact O-CB 3.29Å; L259-T263 WeakPolarHBondContact O-CB 3.25Å; L259-T263 PolarHBondContact O-N 3.31Å; L259-T263 PolarHBondContact O-OG1 2.69Å; L259-L433 HydrophobicContact CD2-CD1 4.15Å; L259-L433 HydrophobicContact CD2-CD2 3.77Å; L259-L433 HydrophobicContact CD2-CG 3.64Å; L259-F437 HydrophobicContact CD1-CB 4.13Å; L259-F437 HydrophobicContact CD2-CB 3.88Å; L259-F437 HydrophobicContact CG-CB 4.48Å; L259-F438 HydrophobicContact CD1-CB 4.07Å; L259-F438 HydrophobicContact CD1-CD2 3.97Å
260V96.4Very high94.6Very high0 Ų033.1 Ų33.10%017%0.17CC..Hα-helixtrans-63.9-45.6176.31630000111.6S256 I257 T258 I262 T263 D264 D366 I369 V370 Y386S256-V260 WeakPolarHBondContact O-CG2 3.43Å; S256-V260 PolarHBondContact O-N 2.89Å; I257-V260 WeakPolarHBondContact O-CB 3.37Å; I257-V260 PolarHBondContact O-N 3.01Å; T258-V260 VanDerWaalsContact C-N 3.32Å; T258-V260 PolarHBondContact O-N 2.89Å; V260-I262 VanDerWaalsContact C-N 3.33Å; V260-I262 PolarHBondContact O-N 2.81Å; V260-T263 PolarHBondContact O-N 3.38Å; V260-D264 WeakPolarHBondContact O-CB 3.21Å; V260-D264 PolarHBondContact O-N 3.5Å; V260-D366 HydrophobicContact CG1-CB 3.57Å; V260-D366 WeakPolarHBondContact CG1-O 3.46Å; V260-I369 HydrophobicContact CG2-CB 4.06Å; V260-I369 HydrophobicContact CG2-CD1 3.83Å; V260-I369 HydrophobicContact CG2-CG2 3.79Å; V260-V370 HydrophobicContact CG1-CG2 3.74Å; V260-Y386 HydrophobicContact CG1-CE2 4.32Å
261F96.4Very high94.7Very high20 Ų2032.8 Ų32.89%0.08817%0.168CC..Hα-helixtrans-61.3-40.1176.9-91.2-99000112.6F253 I257 T258 L265 V370 M382 F385 T389F253-F261 HydrophobicContact CE1-CD1 4.14Å; F253-F261 AromaticContact CE1-CD2 3.81Å; F253-F261 HydrophobicContact CE1-CD2 3.81Å; F253-F261 HydrophobicContact CE1-CE1 4.27Å; F253-F261 AromaticContact CE1-CE2 3.94Å; F253-F261 HydrophobicContact CE1-CE2 3.94Å; F253-F261 AromaticContact CE1-CG 3.91Å; F253-F261 HydrophobicContact CE1-CG 3.91Å; F253-F261 HydrophobicContact CE1-CZ 4.17Å; F253-F261 HydrophobicContact CZ-CE1 4.26Å; F253-F261 HydrophobicContact CZ-CE2 4.27Å; F253-F261 HydrophobicContact CZ-CZ 4.12Å; I257-F261 HydrophobicContact CG2-CD2 3.73Å; I257-F261 HydrophobicContact CG2-CE2 3.75Å; I257-F261 WeakPolarHBondContact O-CD2 3.3Å; I257-F261 PolarHBondContact O-N 2.98Å; T258-F261 PolarHBondContact O-N 3.38Å; F261-L265 WeakPolarHBondContact O-CB 3.2Å; F261-L265 PolarHBondContact O-N 3.43Å; F261-L265 VanDerWaalsContact O-N 3.16Å; F261-V370 HydrophobicContact CD2-CG2 4.39Å; F261-V370 HydrophobicContact CE2-CG1 4.34Å; F261-V370 HydrophobicContact CE2-CG2 3.95Å; F261-M382 HydrophobicContact CE2-CE 3.9Å; F261-M382 HydrophobicContact CZ-CE 4.15Å; F261-F385 HydrophobicContact CE1-CB 4.02Å; F261-F385 HydrophobicContact CZ-CB 4.11Å; F261-T389 HydrophobicContact CD1-CG2 4.19Å; F261-T389 VanDerWaalsContact CD1-OG1 3.25Å; F261-T389 WeakPolarHBondContact CD1-OG1 3.19Å; F261-T389 WeakPolarHBondContact CE1-OG1 3.46Å; F261-T389 WeakPolarHBondContact O-CG2 3.32Å
262I96.6Very high94.5Very high68 Ų6827.7 Ų27.735%0.34914%0.136SC..Hα-helixtrans-66.6-43.1175-65.1166.7000110.5T258 L259 V260 L265 L266 L433T258-I262 HydrophobicContact CG2-CD1 4.12Å; T258-I262 WeakPolarHBondContact O-CG1 3.12Å; T258-I262 PolarHBondContact O-N 3.35Å; T258-I262 VanDerWaalsContact O-N 3.11Å; L259-I262 PolarHBondContact O-N 3.19Å; V260-I262 VanDerWaalsContact C-N 3.33Å; V260-I262 PolarHBondContact O-N 2.81Å; I262-L265 PolarHBondContact O-N 2.9Å; I262-L266 HydrophobicContact CG2-CD1 3.96Å; I262-L266 WeakPolarHBondContact O-CB 3.45Å; I262-L266 WeakPolarHBondContact O-CG 3.42Å; I262-L266 PolarHBondContact O-N 3.37Å; I262-L266 VanDerWaalsContact O-N 3.12Å; I262-L433 HydrophobicContact CB-CD2 4.38Å; I262-L433 HydrophobicContact CG2-CD2 3.72Å
263T97.5Very high94.3Very high0 Ų026 Ų260%013%0.128CC..Hα-helixtrans-62.7-45.6180-58.20000111.1L259 V260 L266 T267 Y324 F328 I362 L430 W434L259-T263 VanDerWaalsContact O-CB 3.29Å; L259-T263 WeakPolarHBondContact O-CB 3.25Å; L259-T263 PolarHBondContact O-N 3.31Å; L259-T263 PolarHBondContact O-OG1 2.69Å; V260-T263 PolarHBondContact O-N 3.38Å; T263-L266 PolarHBondContact O-N 3.11Å; T263-T267 WeakPolarHBondContact O-CB 3.32Å; T263-T267 PolarHBondContact O-N 3.42Å; T263-T267 PolarHBondContact O-OG1 3.39Å; T263-Y324 HydrophobicContact CG2-CE1 4.22Å; T263-F328 HydrophobicContact CG2-CE1 3.74Å; T263-F328 HydrophobicContact CG2-CZ 3.66Å; T263-I362 HydrophobicContact CG2-CG2 3.73Å; T263-L430 HydrophobicContact CG2-CD2 4.24Å; T263-W434 PolarHBondContact OG1-NE1 3.01Å
264D95.9Very high94.2Very high0 Ų023 Ų230%012%0.115CC..Hα-helixtrans-63.2-45.6179.2-176.675.1000111.9V260 L266 T267 A268 D366 Y386 K390V260-D264 WeakPolarHBondContact O-CB 3.21Å; V260-D264 PolarHBondContact O-N 3.5Å; D264-L266 PolarHBondContact O-N 3.2Å; D264-T267 PolarHBondContact O-N 2.83Å; D264-A268 VanDerWaalsContact O-CB 3.27Å; D264-A268 WeakPolarHBondContact O-CB 3.14Å; D264-A268 PolarHBondContact O-N 2.8Å; D264-D366 PolarHBondContact N-OD2 3.43Å; D264-Y386 HydrophobicContact CB-CD2 4.42Å; D264-Y386 HydrophobicContact CB-CE2 3.64Å; D264-Y386 WeakPolarHBondContact OD1-CE2 3.47Å; D264-Y386 PolarHBondContact OD1-OH 2.82Å; D264-K390 VanDerWaalsContact OD2-CA 3.27Å; D264-K390 WeakPolarHBondContact OD2-CA 3.36Å; D264-K390 WeakPolarHBondContact OD2-CB 3.19Å; D264-K390 PolarHBondContact OD2-N 3.08Å; D264-K390 VanDerWaalsContact OD2-N 3.11Å
265L95.7Very high93.8Very high52 Ų5220.7 Ų20.727%0.27210%0.102SC..Hα-helixtrans-57-51.3176.9-174.174.1000111.5F261 I262 A268 I269 T389 L392 I396F261-L265 WeakPolarHBondContact O-CB 3.2Å; F261-L265 PolarHBondContact O-N 3.43Å; F261-L265 VanDerWaalsContact O-N 3.16Å; I262-L265 PolarHBondContact O-N 2.9Å; L265-A268 PolarHBondContact O-N 2.91Å; L265-I269 WeakPolarHBondContact O-CG1 3.26Å; L265-I269 PolarHBondContact O-N 3.37Å; L265-I269 VanDerWaalsContact O-N 3.08Å; L265-T389 HydrophobicContact CB-CG2 3.68Å; L265-T389 HydrophobicContact CD1-CG2 4Å; L265-T389 WeakPolarHBondContact CD1-O 3.44Å; L265-T389 HydrophobicContact CG-CG2 4.43Å; L265-L392 HydrophobicContact CD1-CB 4.2Å; L265-I396 HydrophobicContact CD1-CD1 4.3Å
266L97.2Very high93.4Very high47 Ų4718 Ų1825%0.24610%0.097CC..Hα-helixtrans-68.3-37.5-178.4-70.9179.5000111.9I262 T263 D264 I269 C270 I426 L430I262-L266 HydrophobicContact CG2-CD1 3.96Å; I262-L266 WeakPolarHBondContact O-CB 3.45Å; I262-L266 WeakPolarHBondContact O-CG 3.42Å; I262-L266 PolarHBondContact O-N 3.37Å; I262-L266 VanDerWaalsContact O-N 3.12Å; T263-L266 PolarHBondContact O-N 3.11Å; D264-L266 PolarHBondContact O-N 3.2Å; L266-I269 HydrophobicContact CD2-CD1 4.39Å; L266-I269 WeakPolarHBondContact O-CB 3.15Å; L266-I269 PolarHBondContact O-N 2.93Å; L266-C270 PolarHBondContact O-N 3.41Å; L266-C270 PolarHBondContact O-SG 3.29Å; L266-C270 VanDerWaalsContact O-SG 3.34Å; L266-I426 HydrophobicContact CB-CG2 3.78Å; L266-I426 HydrophobicContact CD1-CG2 4.42Å; L266-I426 HydrophobicContact CD2-CG2 4.29Å; L266-I426 HydrophobicContact CG-CG2 4.38Å; L266-L430 HydrophobicContact CB-CD1 4.2Å; L266-L430 HydrophobicContact CB-CD2 4.26Å; L266-L430 HydrophobicContact CB-CG 4.45Å; L266-L430 HydrophobicContact CD1-CD2 3.7Å; L266-L430 HydrophobicContact CD1-CG 4.08Å
267T96.3Very high93.1Very high0 Ų019.2 Ų19.20%010%0.099CC..Hα-helixtrans-69.1-37177.2-58.30000111.3T263 D264 C270 L271 F359 I362 Y363T263-T267 WeakPolarHBondContact O-CB 3.32Å; T263-T267 PolarHBondContact O-N 3.42Å; T263-T267 PolarHBondContact O-OG1 3.39Å; D264-T267 PolarHBondContact O-N 2.83Å; T267-C270 WeakPolarHBondContact O-CB 3.46Å; T267-C270 PolarHBondContact O-N 2.81Å; T267-L271 WeakPolarHBondContact O-CB 3.35Å; T267-L271 PolarHBondContact O-N 2.97Å; T267-F359 HydrophobicContact CG2-CD1 3.5Å; T267-F359 HydrophobicContact CG2-CE1 3.63Å; T267-I362 HydrophobicContact CG2-CB 4.3Å; T267-I362 HydrophobicContact CG2-CD1 4.18Å; T267-I362 HydrophobicContact CG2-CG2 3.87Å; T267-Y363 HydrophobicContact CG2-CE2 4.01Å
268A94Very high92.9Very high0 Ų019.3 Ų19.30%010%0.099CC..Hα-helixtrans-66-36.5173.200000112.9D264 L265 L271 M272 Y363 K390D264-A268 VanDerWaalsContact O-CB 3.27Å; D264-A268 WeakPolarHBondContact O-CB 3.14Å; D264-A268 PolarHBondContact O-N 2.8Å; L265-A268 PolarHBondContact O-N 2.91Å; A268-L271 PolarHBondContact O-N 3.3Å; A268-M272 PolarHBondContact O-N 2.88Å; A268-Y363 WeakPolarHBondContact CA-OH 3.4Å; A268-K390 HydrophobicContact CB-CG 4.46Å; A268-K390 WeakPolarHBondContact CB-O 3.47Å
269I94.2Very high92.5Very high13 Ų1317.5 Ų17.57%0.0679%0.089CC..Hα-helixtrans-59.7-49.2170.1-71.9167.8000110.4L265 L266 L271 M272 G393 I396 M401 I426L265-I269 WeakPolarHBondContact O-CG1 3.26Å; L265-I269 PolarHBondContact O-N 3.37Å; L265-I269 VanDerWaalsContact O-N 3.08Å; L266-I269 HydrophobicContact CD2-CD1 4.39Å; L266-I269 WeakPolarHBondContact O-CB 3.15Å; L266-I269 PolarHBondContact O-N 2.93Å; I269-L271 PolarHBondContact O-N 3.29Å; I269-M272 PolarHBondContact O-N 2.9Å; I269-G393 WeakPolarHBondContact CA-O 3.47Å; I269-G393 WeakPolarHBondContact CG1-O 3.49Å; I269-G393 PolarHBondContact N-O 3.46Å; I269-I396 HydrophobicContact CD1-CB 4.27Å; I269-I396 HydrophobicContact CD1-CG2 3.73Å; I269-I396 HydrophobicContact CG1-CB 4.19Å; I269-I396 HydrophobicContact CG1-CG2 4.03Å; I269-M401 HydrophobicContact CG2-CE 3.68Å; I269-I426 HydrophobicContact CG2-CD1 3.84Å
270C96.1Very high92.1Very high0 Ų019.4 Ų19.40%010%0.101CC..Hα-helixtrans-60.6-45177-68.30000112L266 T267 M272 G273 F274 L331 F359 V423 I426L266-C270 PolarHBondContact O-N 3.41Å; L266-C270 PolarHBondContact O-SG 3.29Å; L266-C270 VanDerWaalsContact O-SG 3.34Å; T267-C270 WeakPolarHBondContact O-CB 3.46Å; T267-C270 PolarHBondContact O-N 2.81Å; C270-M272 PolarHBondContact O-N 3.43Å; C270-G273 WeakPolarHBondContact O-CA 3.04Å; C270-G273 PolarHBondContact O-N 3.39Å; C270-F274 WeakPolarHBondContact O-CD2 3.24Å; C270-F274 PolarHBondContact O-N 2.73Å; C270-L331 HydrophobicContact CB-CD2 4.16Å; C270-F359 HydrophobicContact CB-CE1 4.33Å; C270-F359 HydrophobicContact CB-CZ 4.33Å; C270-V423 HydrophobicContact CB-CG1 4.17Å; C270-V423 HydrophobicContact CB-CG2 4.17Å; C270-I426 VanDerWaalsContact SG-CG2 3.55Å
271L92.5Very high91.8Very high4 Ų420.4 Ų20.42%0.02111%0.105CC..Hα-helixtrans-56.9-37.9-178.2-17766.9000111.8T267 A268 I269 G273 F274 N275 W304 F359 Y363T267-L271 WeakPolarHBondContact O-CB 3.35Å; T267-L271 PolarHBondContact O-N 2.97Å; A268-L271 PolarHBondContact O-N 3.3Å; I269-L271 PolarHBondContact O-N 3.29Å; L271-G273 VanDerWaalsContact C-N 3.32Å; L271-G273 PolarHBondContact O-N 3.45Å; L271-F274 PolarHBondContact O-N 2.63Å; L271-N275 WeakPolarHBondContact CD1-ND2 3.31Å; L271-N275 WeakPolarHBondContact CG-ND2 3.18Å; L271-N275 WeakPolarHBondContact O-CB 3.29Å; L271-N275 PolarHBondContact O-N 2.52Å; L271-W304 HydrophobicContact CD1-CZ3 4.12Å; L271-W304 HydrophobicContact CD2-CH2 4.47Å; L271-W304 HydrophobicContact CD2-CZ3 4.49Å; L271-F359 HydrophobicContact CB-CD1 4.42Å; L271-F359 HydrophobicContact CB-CE1 3.86Å; L271-F359 HydrophobicContact CB-CZ 4.06Å; L271-F359 HydrophobicContact CD1-CD1 4.12Å; L271-F359 HydrophobicContact CD1-CD2 3.83Å; L271-F359 HydrophobicContact CD1-CE1 4.09Å; L271-F359 HydrophobicContact CD1-CE2 3.79Å; L271-F359 HydrophobicContact CD1-CG 4.01Å; L271-F359 HydrophobicContact CD1-CZ 3.93Å; L271-Y363 HydrophobicContact CD2-CE2 3.78Å; L271-Y363 VanDerWaalsContact CD2-OH 3.31Å; L271-Y363 WeakPolarHBondContact CD2-OH 3.23Å
272M88Confident91.6Very high18 Ų1819.5 Ų19.59%0.08910%0.1CC..Hα-helixtrans-65-35.6175.4-68.3-62.9117.100112.7A268 I269 C270 F274 L276 A394A268-M272 PolarHBondContact O-N 2.88Å; I269-M272 PolarHBondContact O-N 2.9Å; C270-M272 PolarHBondContact O-N 3.43Å; M272-F274 VanDerWaalsContact C-N 3.29Å; M272-F274 PolarHBondContact O-N 2.67Å; M272-L276 HydrophobicContact CB-CD1 4.22Å; M272-L276 VanDerWaalsContact O-CB 3.27Å; M272-L276 WeakPolarHBondContact O-CB 3.41Å; M272-L276 PolarHBondContact O-N 2.83Å; M272-L276 HydrophobicContact SD-CD1 3.87Å; M272-L276 HydrophobicContact SD-CG 4.25Å; M272-A394 HydrophobicContact CE-CB 3.79Å; M272-A394 HydrophobicContact CG-CB 4.04Å; M272-A394 VanDerWaalsContact CG-O 3.3Å; M272-A394 WeakPolarHBondContact CG-O 3.44Å; M272-A394 HydrophobicContact SD-CB 4.01Å
273G88.7Confident91.2Very high0 Ų019.4 Ų19.40%010%0.098CC..Iπ-helixtrans-57.4-42.9172.400000112.3C270 L271 Y277 V419C270-G273 WeakPolarHBondContact O-CA 3.04Å; C270-G273 PolarHBondContact O-N 3.39Å; L271-G273 VanDerWaalsContact C-N 3.32Å; L271-G273 PolarHBondContact O-N 3.45Å; G273-Y277 WeakPolarHBondContact O-CB 3.22Å; G273-Y277 PolarHBondContact O-N 3.34Å; G273-V419 VanDerWaalsContact CA-CG1 3.49Å
274F90.4Very high90.8Very high1 Ų125.2 Ų25.20%0.00413%0.126CC..Iπ-helixtrans-72.9-54.1176.2-73.5-97.5000112.4C270 L271 M272 L276 I278 P279 L300 L331 L352 A355 F359 L420 V423C270-F274 WeakPolarHBondContact O-CD2 3.24Å; C270-F274 PolarHBondContact O-N 2.73Å; L271-F274 PolarHBondContact O-N 2.63Å; M272-F274 VanDerWaalsContact C-N 3.29Å; M272-F274 PolarHBondContact O-N 2.67Å; F274-L276 PolarHBondContact O-N 2.81Å; F274-I278 HydrophobicContact CB-CD1 4.1Å; F274-I278 HydrophobicContact CD1-CD1 3.38Å; F274-I278 HydrophobicContact CE1-CD1 4.06Å; F274-I278 HydrophobicContact CG-CD1 3.99Å; F274-I278 VanDerWaalsContact O-CB 3.25Å; F274-I278 WeakPolarHBondContact O-CB 3.38Å; F274-I278 WeakPolarHBondContact O-CG1 3.27Å; F274-I278 PolarHBondContact O-N 3.41Å; F274-P279 WeakPolarHBondContact O-CD 3.33Å; F274-L300 HydrophobicContact CB-CD1 4.35Å; F274-L300 HydrophobicContact CD1-CD1 4.41Å; F274-L331 HydrophobicContact CE2-CD1 3.63Å; F274-L331 HydrophobicContact CZ-CD1 3.82Å; F274-L352 HydrophobicContact CD1-CD2 3.52Å; F274-L352 HydrophobicContact CE1-CD2 3.85Å; F274-A355 HydrophobicContact CD1-CB 3.94Å; F274-A355 HydrophobicContact CE1-CB 3.55Å; F274-A355 HydrophobicContact CZ-CB 3.99Å; F274-F359 HydrophobicContact CB-CE2 4.48Å; F274-F359 AromaticContact CD2-CE2 3.91Å; F274-F359 HydrophobicContact CD2-CE2 3.91Å; F274-F359 AromaticContact CD2-CZ 3.83Å; F274-F359 HydrophobicContact CD2-CZ 3.83Å; F274-F359 HydrophobicContact CE2-CE2 4.33Å; F274-F359 HydrophobicContact CE2-CZ 4.18Å; F274-F359 HydrophobicContact CG-CE2 4.12Å; F274-F359 HydrophobicContact CG-CZ 4.46Å; F274-L420 HydrophobicContact CE1-CD2 4.34Å; F274-L420 HydrophobicContact CE2-CD2 4.45Å; F274-L420 HydrophobicContact CZ-CD2 4.06Å; F274-V423 HydrophobicContact CE2-CB 4.5Å; F274-V423 HydrophobicContact CE2-CG1 3.82Å; F274-V423 HydrophobicContact CE2-CG2 4.09Å; F274-V423 HydrophobicContact CZ-CG1 4.39Å
275N83.6Confident90.5Very high15 Ų1530.1 Ų30.18%0.0815%0.149CC..Iπ-helixtrans-73.4-29.5-170.6-82.8-21.3000114L271 P279L271-N275 WeakPolarHBondContact CD1-ND2 3.31Å; L271-N275 WeakPolarHBondContact CG-ND2 3.18Å; L271-N275 WeakPolarHBondContact O-CB 3.29Å; L271-N275 PolarHBondContact O-N 2.52Å; N275-P279 WeakPolarHBondContact O-CD 3.47Å; N275-P279 WeakPolarHBondContact O-CG 3.44Å
276L82.1Confident90.3Very high60 Ų6029.8 Ų29.831%0.31415%0.147SC..Iπ-helixtrans-95.5-50.6179.5-63.5174.3000111.8M272 F274 P279 V280M272-L276 HydrophobicContact CB-CD1 4.22Å; M272-L276 VanDerWaalsContact O-CB 3.27Å; M272-L276 WeakPolarHBondContact O-CB 3.41Å; M272-L276 PolarHBondContact O-N 2.83Å; M272-L276 HydrophobicContact SD-CD1 3.87Å; M272-L276 HydrophobicContact SD-CG 4.25Å; F274-L276 PolarHBondContact O-N 2.81Å; L276-P279 WeakPolarHBondContact O-CD 3.45Å; L276-P279 WeakPolarHBondContact O-CG 3.13Å; L276-V280 WeakPolarHBondContact O-CG2 3.03Å; L276-V280 PolarHBondContact O-N 3.18Å
277Y87.6Confident89.9Confident42 Ų4230.7 Ų30.717%0.16517%0.167CC..Iπ-helixtrans-92.3-19.8-166-69-73.8000115G273 Y281 S398 M401 G402 Y405 V419G273-Y277 WeakPolarHBondContact O-CB 3.22Å; G273-Y277 PolarHBondContact O-N 3.34Å; Y277-Y281 VanDerWaalsContact O-CB 3.24Å; Y277-Y281 WeakPolarHBondContact O-CB 3.49Å; Y277-Y281 PolarHBondContact O-N 3.45Å; Y277-S398 PolarHBondContact OH-O 3.42Å; Y277-M401 HydrophobicContact CD2-CB 3.58Å; Y277-M401 VanDerWaalsContact CE2-C 3.49Å; Y277-M401 HydrophobicContact CE2-CB 3.58Å; Y277-G402 WeakPolarHBondContact OH-CA 3.42Å; Y277-G402 PolarHBondContact OH-N 3.17Å; Y277-Y405 AromaticContact CD1-CD1 3.88Å; Y277-Y405 HydrophobicContact CD1-CD1 3.88Å; Y277-Y405 AromaticContact CD1-CD2 3.59Å; Y277-Y405 HydrophobicContact CD1-CD2 3.59Å; Y277-Y405 HydrophobicContact CD1-CE1 4.5Å; Y277-Y405 HydrophobicContact CD1-CE2 4.24Å; Y277-Y405 AromaticContact CD1-CG 3.39Å; Y277-Y405 HydrophobicContact CD1-CG 3.39Å; Y277-Y405 HydrophobicContact CE1-CD1 4.13Å; Y277-Y405 AromaticContact CE1-CG 3.91Å; Y277-Y405 HydrophobicContact CE1-CG 3.91Å; Y277-Y405 HydrophobicContact CG-CD2 4.07Å; Y277-Y405 HydrophobicContact CG-CG 4.2Å; Y277-V419 HydrophobicContact CG-CG2 4.38Å
278I89.8Confident89.7Confident1 Ų132.2 Ų32.21%0.00518%0.175CC..Hα-helixtrans-66.1-50.2168-62.1-178.1000111.5F274 V280 Y281 L282 I297 I338 I348 L352 L416F274-I278 HydrophobicContact CB-CD1 4.1Å; F274-I278 HydrophobicContact CD1-CD1 3.38Å; F274-I278 HydrophobicContact CE1-CD1 4.06Å; F274-I278 HydrophobicContact CG-CD1 3.99Å; F274-I278 VanDerWaalsContact O-CB 3.25Å; F274-I278 WeakPolarHBondContact O-CB 3.38Å; F274-I278 WeakPolarHBondContact O-CG1 3.27Å; F274-I278 PolarHBondContact O-N 3.41Å; I278-V280 VanDerWaalsContact C-N 3.29Å; I278-V280 PolarHBondContact O-N 2.82Å; I278-Y281 PolarHBondContact O-N 3.39Å; I278-L282 HydrophobicContact CG2-CD1 3.86Å; I278-L282 HydrophobicContact CG2-CG 4.1Å; I278-L282 WeakPolarHBondContact O-CB 3.24Å; I278-L282 WeakPolarHBondContact O-CG 3.07Å; I278-L282 PolarHBondContact O-N 3.44Å; I278-I297 HydrophobicContact CG2-CD1 4.47Å; I278-I297 HydrophobicContact CG2-CG1 4.17Å; I278-I338 HydrophobicContact CD1-CD1 4.37Å; I278-I348 HydrophobicContact CG2-CG2 4.45Å; I278-L352 HydrophobicContact CD1-CD2 3.6Å; I278-L352 HydrophobicContact CG2-CD1 4.39Å; I278-L416 HydrophobicContact CG1-CD1 3.78Å; I278-L416 HydrophobicContact CG1-CD2 4.17Å
279P88.1Confident89.5Confident19 Ų1934.5 Ų34.512%0.12319%0.191CC..Hα-helixtrans-62-38.517811.2-14.8000112.2F274 N275 L276 L282 Q283 I297F274-P279 WeakPolarHBondContact O-CD 3.33Å; N275-P279 WeakPolarHBondContact O-CD 3.47Å; N275-P279 WeakPolarHBondContact O-CG 3.44Å; L276-P279 WeakPolarHBondContact O-CD 3.45Å; L276-P279 WeakPolarHBondContact O-CG 3.13Å; P279-L282 PolarHBondContact O-N 3.12Å; P279-Q283 VanDerWaalsContact O-CG 3.26Å; P279-Q283 WeakPolarHBondContact O-CG 3.29Å; P279-Q283 PolarHBondContact O-N 3.4Å; P279-Q283 PolarHBondContact O-NE2 3.25Å; P279-I297 HydrophobicContact CB-CD1 3.48Å; P279-I297 VanDerWaalsContact CB-CD1 3.48Å; P279-I297 HydrophobicContact CG-CD1 3.31Å
280V87.8Confident88.9Confident48 Ų4836 Ų3629%0.29120%0.202SC..Hα-helixtrans-60.3-47.8174.3173.80000110.9L276 I278 L282 Q283 E284 Y405L276-V280 WeakPolarHBondContact O-CG2 3.03Å; L276-V280 PolarHBondContact O-N 3.18Å; I278-V280 VanDerWaalsContact C-N 3.29Å; I278-V280 PolarHBondContact O-N 2.82Å; V280-L282 PolarHBondContact O-N 3.16Å; V280-Q283 PolarHBondContact O-N 3.37Å; V280-E284 VanDerWaalsContact CG1-CD 3.48Å; V280-E284 HydrophobicContact CG1-CG 4.14Å; V280-E284 WeakPolarHBondContact CG1-OE2 3.44Å; V280-E284 WeakPolarHBondContact O-CB 3.26Å; V280-E284 WeakPolarHBondContact O-CG 3.22Å; V280-E284 PolarHBondContact O-N 3.26Å; V280-Y405 HydrophobicContact CG1-CE1 3.87Å
281Y89.7Confident88.5Confident21 Ų2139.3 Ų39.38%0.08222%0.219CC..Hα-helixtrans-59.8-44.9176.1174.9-97.7000113Y277 I278 Q283 Q285 L286 L416Y277-Y281 VanDerWaalsContact O-CB 3.24Å; Y277-Y281 WeakPolarHBondContact O-CB 3.49Å; Y277-Y281 PolarHBondContact O-N 3.45Å; I278-Y281 PolarHBondContact O-N 3.39Å; Y281-Q283 VanDerWaalsContact C-N 3.26Å; Y281-Q283 PolarHBondContact O-N 3.04Å; Y281-Q285 HydrophobicContact CD2-CB 3.94Å; Y281-Q285 HydrophobicContact CD2-CG 3.73Å; Y281-Q285 HydrophobicContact CE2-CB 3.78Å; Y281-Q285 HydrophobicContact CE2-CG 3.79Å; Y281-Q285 WeakPolarHBondContact O-CA 3.45Å; Y281-Q285 VanDerWaalsContact O-CB 3.31Å; Y281-Q285 WeakPolarHBondContact O-CB 3.13Å; Y281-Q285 PolarHBondContact O-N 2.68Å; Y281-L286 HydrophobicContact CE1-CD1 4.37Å; Y281-L286 HydrophobicContact CE1-CG 4.32Å; Y281-L416 HydrophobicContact CD1-CD2 3.49Å; Y281-L416 VanDerWaalsContact CD1-CD2 3.49Å; Y281-L416 HydrophobicContact CD2-CB 3.6Å; Y281-L416 HydrophobicContact CD2-CD2 4.12Å; Y281-L416 HydrophobicContact CE1-CD2 4.08Å; Y281-L416 HydrophobicContact CE2-CB 4.23Å; Y281-L416 HydrophobicContact CG-CB 3.78Å; Y281-L416 HydrophobicContact CG-CD2 3.51Å; Y281-L416 HydrophobicContact CG-CG 4.24Å
282L91.1Very high88.4Confident0 Ų043.7 Ų43.70%024%0.239CC..Hα-helixtrans-61.3-36.2178.7-70175.6000111.8I278 P279 V280 L286 G287 L288 V296 I348I278-L282 HydrophobicContact CG2-CD1 3.86Å; I278-L282 HydrophobicContact CG2-CG 4.1Å; I278-L282 WeakPolarHBondContact O-CB 3.24Å; I278-L282 WeakPolarHBondContact O-CG 3.07Å; I278-L282 PolarHBondContact O-N 3.44Å; P279-L282 PolarHBondContact O-N 3.12Å; V280-L282 PolarHBondContact O-N 3.16Å; L282-L286 HydrophobicContact CD2-CD1 3.63Å; L282-L286 CarbonylContact O-C 3.47Å; L282-L286 WeakPolarHBondContact O-CB 3.1Å; L282-L286 PolarHBondContact O-N 3.49Å; L282-G287 PolarHBondContact O-N 2.87Å; L282-L288 HydrophobicContact CB-CD1 4.23Å; L282-L288 HydrophobicContact CD2-CD1 4.3Å; L282-L288 WeakPolarHBondContact O-CB 3.48Å; L282-L288 PolarHBondContact O-N 3.35Å; L282-L288 VanDerWaalsContact O-N 3.09Å; L282-V296 HydrophobicContact CD1-CB 3.62Å; L282-V296 HydrophobicContact CD1-CG1 3.53Å; L282-V296 HydrophobicContact CD1-CG2 4.18Å; L282-V296 HydrophobicContact CD2-CG1 4.27Å; L282-I348 HydrophobicContact CD2-CD1 3.66Å
283Q89.9Confident88.5Confident66 Ų6642.9 Ų42.931%0.30824%0.236SC..Hα-helixtrans-78.2-51.7178.6-68.117458.100111.6P279 V280 Y281 G287 L288 S293P279-Q283 VanDerWaalsContact O-CG 3.26Å; P279-Q283 WeakPolarHBondContact O-CG 3.29Å; P279-Q283 PolarHBondContact O-N 3.4Å; P279-Q283 PolarHBondContact O-NE2 3.25Å; V280-Q283 PolarHBondContact O-N 3.37Å; Y281-Q283 VanDerWaalsContact C-N 3.26Å; Y281-Q283 PolarHBondContact O-N 3.04Å; Q283-G287 VanDerWaalsContact O-CA 3.25Å; Q283-G287 WeakPolarHBondContact O-CA 3.38Å; Q283-G287 PolarHBondContact O-N 2.99Å; Q283-G287 VanDerWaalsContact O-N 3.16Å; Q283-L288 WeakPolarHBondContact CA-O 3.48Å; Q283-L288 WeakPolarHBondContact CG-O 3.49Å; Q283-S293 PolarHBondContact NE2-OG 3.47Å
284E88.8Confident88.4Confident123 Ų12343 Ų4358%0.57524%0.237SC*.Hα-helixtrans-72.9-38.8-174.3-68.5-179.5163.800113.2V280 Y405V280-E284 VanDerWaalsContact CG1-CD 3.48Å; V280-E284 HydrophobicContact CG1-CG 4.14Å; V280-E284 WeakPolarHBondContact CG1-OE2 3.44Å; V280-E284 WeakPolarHBondContact O-CB 3.26Å; V280-E284 WeakPolarHBondContact O-CG 3.22Å; V280-E284 PolarHBondContact O-N 3.26Å; E284-Y405 WeakPolarHBondContact OE2-CE1 3.27Å; E284-Y405 PolarHBondContact OE2-OH 2.91Å
285Q89Confident88.4Confident102 Ų10247.4 Ų47.448%0.47726%0.26SS..THydrogen-bonded Turntrans-103.8-30.3-172.2-62.3-64.6-5.900114.1Y281 N415Y281-Q285 HydrophobicContact CD2-CB 3.94Å; Y281-Q285 HydrophobicContact CD2-CG 3.73Å; Y281-Q285 HydrophobicContact CE2-CB 3.78Å; Y281-Q285 HydrophobicContact CE2-CG 3.79Å; Y281-Q285 WeakPolarHBondContact O-CA 3.45Å; Y281-Q285 VanDerWaalsContact O-CB 3.31Å; Y281-Q285 WeakPolarHBondContact O-CB 3.13Å; Y281-Q285 PolarHBondContact O-N 2.68Å; Q285-N415 PolarHBondContact NE2-ND2 3.44Å; Q285-N415 VanDerWaalsContact NE2-ND2 3.19Å
286L90.8Very high88.9Confident46 Ų4647.3 Ų47.324%0.24126%0.26CS..THydrogen-bonded Turntrans-102.7-0.9176-55.6-176.7000113.1Y281 L282 L288 K343 P345 I348Y281-L286 HydrophobicContact CE1-CD1 4.37Å; Y281-L286 HydrophobicContact CE1-CG 4.32Å; L282-L286 HydrophobicContact CD2-CD1 3.63Å; L282-L286 CarbonylContact O-C 3.47Å; L282-L286 WeakPolarHBondContact O-CB 3.1Å; L282-L286 PolarHBondContact O-N 3.49Å; L286-L288 HydrophobicContact CB-CG 4.25Å; L286-L288 PolarHBondContact O-N 3.42Å; L286-K343 WeakPolarHBondContact CD1-O 3.43Å; L286-K343 HydrophobicContact CD2-CB 4.24Å; L286-P345 HydrophobicContact CD1-CG 4.34Å; L286-I348 HydrophobicContact CD1-CD1 4.02Å
287G89.8Confident89.3Confident65 Ų6544.5 Ų44.567%0.6725%0.245SC*.  trans6520.9176.400000114L282 Q283L282-G287 PolarHBondContact O-N 2.87Å; Q283-G287 VanDerWaalsContact O-CA 3.25Å; Q283-G287 WeakPolarHBondContact O-CA 3.38Å; Q283-G287 PolarHBondContact O-N 2.99Å; Q283-G287 VanDerWaalsContact O-N 3.16Å
288L91.4Very high89.4Confident33 Ų3346.2 Ų46.217%0.17325%0.254CS..  trans-74.1148.8178.5-63.8-173.3000110.8L282 Q283 L286 Q292 V296 P345L282-L288 HydrophobicContact CB-CD1 4.23Å; L282-L288 HydrophobicContact CD2-CD1 4.3Å; L282-L288 WeakPolarHBondContact O-CB 3.48Å; L282-L288 PolarHBondContact O-N 3.35Å; L282-L288 VanDerWaalsContact O-N 3.09Å; Q283-L288 WeakPolarHBondContact CA-O 3.48Å; Q283-L288 WeakPolarHBondContact CG-O 3.49Å; L286-L288 HydrophobicContact CB-CG 4.25Å; L286-L288 PolarHBondContact O-N 3.42Å; L288-Q292 HydrophobicContact CB-CB 3.98Å; L288-Q292 HydrophobicContact CD1-CB 4.39Å; L288-Q292 HydrophobicContact CD2-CB 4.4Å; L288-Q292 HydrophobicContact CG-CB 4.49Å; L288-V296 HydrophobicContact CD1-CG2 4.2Å; L288-P345 HydrophobicContact CD1-CB 4.03Å; L288-P345 HydrophobicContact CD1-CG 3.87Å; L288-P345 HydrophobicContact CD2-CG 4.48Å
289S89.1Confident89.6Confident48 Ų4847.6 Ų47.634%0.33626%0.263SS..  trans-66.5159.5168.9620000111.7L291 Q292 S293S289-L291 VanDerWaalsContact C-N 3.26Å; S289-L291 PolarHBondContact O-N 3.06Å; S289-Q292 PolarHBondContact O-N 2.95Å; S289-Q292 VanDerWaalsContact O-N 3.11Å; S289-Q292 WeakPolarHBondContact OG-CB 3.49Å; S289-Q292 VanDerWaalsContact OG-CD 3.24Å; S289-Q292 VanDerWaalsContact OG-CG 3.23Å; S289-Q292 WeakPolarHBondContact OG-CG 3.42Å; S289-Q292 PolarHBondContact OG-N 3.32Å; S289-Q292 PolarHBondContact OG-OE1 2.94Å; S289-S293 PolarHBondContact O-N 3.45Å
290P83.3Confident89.9Confident44 Ų4446.8 Ų46.829%0.28626%0.257SS..Hα-helixtrans-52.2-43174-28.434.8000113.1L28 P147 S293 G294L28-P290 HydrophobicContact CD2-CB 4.48Å; L28-P290 HydrophobicContact CD2-CG 4.28Å; P147-P290 HydrophobicContact CB-CB 3.75Å; P147-P290 HydrophobicContact CG-CB 4.45Å; P290-S293 PolarHBondContact O-N 3.32Å; P290-S293 PolarHBondContact O-OG 3.1Å; P290-G294 PolarHBondContact O-N 3.5Å
291L86.4Confident90.1Very high70 Ų7044.6 Ų44.637%0.36624%0.244SC..Hα-helixtrans-62.4-47177179.662.4000112.1I144 S289 S293 G294 L295I144-L291 HydrophobicContact CG2-CD1 3.98Å; S289-L291 VanDerWaalsContact C-N 3.26Å; S289-L291 PolarHBondContact O-N 3.06Å; L291-S293 VanDerWaalsContact C-N 3.32Å; L291-S293 PolarHBondContact O-N 3.34Å; L291-G294 PolarHBondContact O-N 3.09Å; L291-L295 HydrophobicContact CG-CD1 4.43Å; L291-L295 WeakPolarHBondContact O-CG 3.13Å; L291-L295 PolarHBondContact O-N 2.82Å
292Q90.9Very high90.4Very high95 Ų9546.6 Ų46.644%0.44426%0.259SS..Hα-helixtrans-62-40.5177.2-74.9165.2-3200111.5L288 S289 G294 L295 V296L288-Q292 HydrophobicContact CB-CB 3.98Å; L288-Q292 HydrophobicContact CD1-CB 4.39Å; L288-Q292 HydrophobicContact CD2-CB 4.4Å; L288-Q292 HydrophobicContact CG-CB 4.49Å; S289-Q292 PolarHBondContact O-N 2.95Å; S289-Q292 VanDerWaalsContact O-N 3.11Å; S289-Q292 WeakPolarHBondContact OG-CB 3.49Å; S289-Q292 VanDerWaalsContact OG-CD 3.24Å; S289-Q292 VanDerWaalsContact OG-CG 3.23Å; S289-Q292 WeakPolarHBondContact OG-CG 3.42Å; S289-Q292 PolarHBondContact OG-N 3.32Å; S289-Q292 PolarHBondContact OG-OE1 2.94Å; Q292-G294 PolarHBondContact O-N 2.8Å; Q292-L295 PolarHBondContact O-N 2.99Å; Q292-V296 WeakPolarHBondContact O-CG2 3.29Å; Q292-V296 PolarHBondContact O-N 3.29Å
293S89.4Confident90.7Very high2 Ų246.9 Ų46.91%0.01426%0.26CS..Hα-helixtrans-63.7-40.1176.4780000112.3Q283 S289 P290 L291 V296 I297Q283-S293 PolarHBondContact NE2-OG 3.47Å; S289-S293 PolarHBondContact O-N 3.45Å; P290-S293 PolarHBondContact O-N 3.32Å; P290-S293 PolarHBondContact O-OG 3.1Å; L291-S293 VanDerWaalsContact C-N 3.32Å; L291-S293 PolarHBondContact O-N 3.34Å; S293-V296 PolarHBondContact O-N 2.66Å; S293-I297 WeakPolarHBondContact O-CD1 3.38Å; S293-I297 WeakPolarHBondContact O-CG1 3.26Å; S293-I297 PolarHBondContact O-N 2.8Å
294G87.6Confident90.9Very high2 Ų244 Ų442%0.02125%0.247CC..Hα-helixtrans-63.2-41.1173.700000112.5P290 L291 Q292 V296 I297 F298P290-G294 PolarHBondContact O-N 3.5Å; L291-G294 PolarHBondContact O-N 3.09Å; Q292-G294 PolarHBondContact O-N 2.8Å; G294-V296 VanDerWaalsContact C-N 3.32Å; G294-V296 PolarHBondContact O-N 2.89Å; G294-I297 PolarHBondContact O-N 3.31Å; G294-F298 PolarHBondContact O-N 3.26Å
295L91.1Very high91.2Very high93 Ų9340.2 Ų40.249%0.48723%0.23SC..Hα-helixtrans-64.8-33.5176.4-72.2174.3000113I144 L291 Q292 I297 P299I144-L295 HydrophobicContact CD1-CD2 4.25Å; L291-L295 HydrophobicContact CG-CD1 4.43Å; L291-L295 WeakPolarHBondContact O-CG 3.13Å; L291-L295 PolarHBondContact O-N 2.82Å; Q292-L295 PolarHBondContact O-N 2.99Å; L295-I297 VanDerWaalsContact C-N 3.31Å; L295-P299 WeakPolarHBondContact O-CD 3.42Å
296V92.6Very high91.6Very high13 Ų1338.8 Ų38.88%0.07923%0.228CC..Hα-helixtrans-67.1-34.2174.5172.40000111.3L282 L288 Q292 S293 G294 P299 P345 I348 A349 L352L282-V296 HydrophobicContact CD1-CB 3.62Å; L282-V296 HydrophobicContact CD1-CG1 3.53Å; L282-V296 HydrophobicContact CD1-CG2 4.18Å; L282-V296 HydrophobicContact CD2-CG1 4.27Å; L288-V296 HydrophobicContact CD1-CG2 4.2Å; Q292-V296 WeakPolarHBondContact O-CG2 3.29Å; Q292-V296 PolarHBondContact O-N 3.29Å; S293-V296 PolarHBondContact O-N 2.66Å; G294-V296 VanDerWaalsContact C-N 3.32Å; G294-V296 PolarHBondContact O-N 2.89Å; V296-P299 WeakPolarHBondContact O-CD 3.46Å; V296-P345 HydrophobicContact CG2-CB 3.74Å; V296-I348 HydrophobicContact CG1-CB 4.09Å; V296-I348 HydrophobicContact CG1-CG2 3.85Å; V296-A349 HydrophobicContact CG1-CB 4.18Å; V296-A349 WeakPolarHBondContact O-CA 3.17Å; V296-A349 WeakPolarHBondContact O-CB 3.08Å; V296-L352 HydrophobicContact CG1-CD1 4.45Å; V296-L352 WeakPolarHBondContact O-CD1 3.43Å
297I90.3Very high91.8Very high2 Ų237.8 Ų37.81%0.0122%0.223CC..Hα-helixtrans-81.9-27.3-179.1-63160.1000112.2I278 P279 S293 G294 L295 P299 L300 L352I278-I297 HydrophobicContact CG2-CD1 4.47Å; I278-I297 HydrophobicContact CG2-CG1 4.17Å; P279-I297 HydrophobicContact CB-CD1 3.48Å; P279-I297 VanDerWaalsContact CB-CD1 3.48Å; P279-I297 HydrophobicContact CG-CD1 3.31Å; S293-I297 WeakPolarHBondContact O-CD1 3.38Å; S293-I297 WeakPolarHBondContact O-CG1 3.26Å; S293-I297 PolarHBondContact O-N 2.8Å; G294-I297 PolarHBondContact O-N 3.31Å; L295-I297 VanDerWaalsContact C-N 3.31Å; I297-P299 VanDerWaalsContact C-N 3.33Å; I297-P299 VanDerWaalsContact O-N 3.14Å; I297-L300 WeakPolarHBondContact O-CB 3.45Å; I297-L300 PolarHBondContact O-N 3.23Å; I297-L352 HydrophobicContact CB-CD1 4.39Å; I297-L352 HydrophobicContact CG1-CD1 4.11Å
298F91.1Very high92.1Very high78 Ų7834.7 Ų34.734%0.34219%0.192SC..Hα-helixtrans-49.2-39.9-175.7-176.7-118000116.3I141 I144 G294 L300 S301 V302I141-F298 HydrophobicContact CG1-CE2 4.19Å; I144-F298 HydrophobicContact CD1-CB 3.6Å; I144-F298 HydrophobicContact CD1-CD1 4.26Å; I144-F298 HydrophobicContact CD1-CD2 3.18Å; I144-F298 HydrophobicContact CD1-CE2 3.82Å; I144-F298 HydrophobicContact CD1-CG 3.42Å; I144-F298 VanDerWaalsContact CD1-CG 3.42Å; I144-F298 HydrophobicContact CG1-CB 4.31Å; I144-F298 HydrophobicContact CG1-CD2 4.37Å; G294-F298 PolarHBondContact O-N 3.26Å; F298-L300 PolarHBondContact O-N 3.43Å; F298-L300 VanDerWaalsContact O-N 3.11Å; F298-S301 WeakPolarHBondContact O-CB 3.38Å; F298-S301 PolarHBondContact O-N 3.28Å; F298-V302 HydrophobicContact CD1-CG2 4.01Å; F298-V302 HydrophobicContact CE1-CG2 3.62Å; F298-V302 HydrophobicContact CE2-CG2 4.38Å; F298-V302 HydrophobicContact CZ-CG2 3.84Å; F298-V302 PolarHBondContact O-N 2.86Å
299P93.8Very high92.4Very high29 Ų2937 Ų3719%0.18820%0.2CC..Hα-helixtrans-57.1-26.4176.1-28.939.6000114.4L295 V296 I297 S301 V302 A303 A349 I353L295-P299 WeakPolarHBondContact O-CD 3.42Å; V296-P299 WeakPolarHBondContact O-CD 3.46Å; I297-P299 VanDerWaalsContact C-N 3.33Å; I297-P299 VanDerWaalsContact O-N 3.14Å; P299-S301 VanDerWaalsContact C-N 3.3Å; P299-S301 PolarHBondContact O-N 3.31Å; P299-V302 PolarHBondContact O-N 2.88Å; P299-A303 VanDerWaalsContact O-CB 3.28Å; P299-A303 WeakPolarHBondContact O-CB 3.44Å; P299-A303 PolarHBondContact O-N 2.93Å; P299-A349 HydrophobicContact CG-CB 4.14Å; P299-I353 HydrophobicContact CB-CD1 4.43Å; P299-I353 HydrophobicContact CB-CG1 3.79Å
300L94.2Very high92.8Very high2 Ų237.4 Ų37.41%0.0120%0.198CC..Hα-helixtrans-56.6-45.8171.3-174152.7000110.9F274 I297 F298 W304 L352 A355 G356 F359F274-L300 HydrophobicContact CB-CD1 4.35Å; F274-L300 HydrophobicContact CD1-CD1 4.41Å; I297-L300 WeakPolarHBondContact O-CB 3.45Å; I297-L300 PolarHBondContact O-N 3.23Å; F298-L300 PolarHBondContact O-N 3.43Å; F298-L300 VanDerWaalsContact O-N 3.11Å; L300-W304 HydrophobicContact CD2-CE3 4.02Å; L300-W304 WeakPolarHBondContact O-CB 3.33Å; L300-W304 PolarHBondContact O-N 3.47Å; L300-L352 HydrophobicContact CB-CB 4.29Å; L300-L352 HydrophobicContact CD1-CD2 4.4Å; L300-A355 HydrophobicContact CD1-CB 4.22Å; L300-G356 VanDerWaalsContact O-CA 3.27Å; L300-G356 WeakPolarHBondContact O-CA 3.34Å; L300-F359 HydrophobicContact CD1-CD2 4.34Å; L300-F359 HydrophobicContact CD1-CE2 4.39Å
301S92.7Very high93.4Very high2 Ų235.3 Ų35.31%0.01419%0.185CC..Hα-helixtrans-70.5-39.7179.4-68.10000112.1S137 G140 F298 P299 A303 W304 I305S137-S301 PolarHBondContact O-OG 2.94Å; G140-S301 WeakPolarHBondContact CA-OG 2.9Å; G140-S301 PolarHBondContact N-OG 2.78Å; F298-S301 WeakPolarHBondContact O-CB 3.38Å; F298-S301 PolarHBondContact O-N 3.28Å; P299-S301 VanDerWaalsContact C-N 3.3Å; P299-S301 PolarHBondContact O-N 3.31Å; S301-A303 VanDerWaalsContact C-N 3.34Å; S301-A303 PolarHBondContact O-N 3.44Å; S301-W304 WeakPolarHBondContact O-CB 3.28Å; S301-W304 PolarHBondContact O-N 2.74Å; S301-I305 VanDerWaalsContact O-CG1 3.3Å; S301-I305 WeakPolarHBondContact O-CG1 3.27Å; S301-I305 PolarHBondContact O-N 3.06Å
302V95.3Very high93.8Very high64 Ų6434.9 Ų34.939%0.38818%0.181SC..Hα-helixtrans-60.9-45.7175.91790000110.6F298 P299 I305 T306F298-V302 HydrophobicContact CD1-CG2 4.01Å; F298-V302 HydrophobicContact CE1-CG2 3.62Å; F298-V302 HydrophobicContact CE2-CG2 4.38Å; F298-V302 HydrophobicContact CZ-CG2 3.84Å; F298-V302 PolarHBondContact O-N 2.86Å; P299-V302 PolarHBondContact O-N 2.88Å; V302-I305 PolarHBondContact O-N 3.48Å; V302-T306 VanDerWaalsContact O-CB 3.28Å; V302-T306 WeakPolarHBondContact O-CB 3.31Å; V302-T306 PolarHBondContact O-N 3.28Å; V302-T306 PolarHBondContact O-OG1 3.46Å
303A96.5Very high94.1Very high5 Ų537.8 Ų37.84%0.04119%0.188CC..Hα-helixtrans-63.1-43.5177.300000112P299 S301 I305 T306 L307 I353 L357P299-A303 VanDerWaalsContact O-CB 3.28Å; P299-A303 WeakPolarHBondContact O-CB 3.44Å; P299-A303 PolarHBondContact O-N 2.93Å; S301-A303 VanDerWaalsContact C-N 3.34Å; S301-A303 PolarHBondContact O-N 3.44Å; A303-I305 PolarHBondContact O-N 3.49Å; A303-T306 PolarHBondContact O-N 3.26Å; A303-L307 WeakPolarHBondContact O-CB 3.34Å; A303-L307 PolarHBondContact O-N 2.96Å; A303-I353 HydrophobicContact CB-CB 4.27Å; A303-I353 HydrophobicContact CB-CG2 3.81Å; A303-I353 WeakPolarHBondContact CB-O 3.35Å; A303-L357 HydrophobicContact CB-CD2 4.13Å; A303-L357 HydrophobicContact CB-CG 4.16Å
304W95Very high94.4Very high5 Ų539.8 Ų39.82%0.01920%0.198CC..Hα-helixtrans-54.7-52.7174.6-172.9-43000111.4L271 L300 S301 N308 G356 F359 G360 Y363L271-W304 HydrophobicContact CD1-CZ3 4.12Å; L271-W304 HydrophobicContact CD2-CH2 4.47Å; L271-W304 HydrophobicContact CD2-CZ3 4.49Å; L300-W304 HydrophobicContact CD2-CE3 4.02Å; L300-W304 WeakPolarHBondContact O-CB 3.33Å; L300-W304 PolarHBondContact O-N 3.47Å; S301-W304 WeakPolarHBondContact O-CB 3.28Å; S301-W304 PolarHBondContact O-N 2.74Å; W304-N308 PolarHBondContact O-N 3.14Å; W304-N308 PolarHBondContact O-ND2 2.91Å; W304-G356 VanDerWaalsContact CA-O 3.3Å; W304-G356 WeakPolarHBondContact CA-O 3.41Å; W304-F359 HydrophobicContact CD2-CB 4.21Å; W304-F359 HydrophobicContact CE3-CB 3.65Å; W304-F359 HydrophobicContact CH2-CB 4.17Å; W304-F359 HydrophobicContact CZ3-CB 3.64Å; W304-F359 HydrophobicContact CZ3-CG 4.34Å; W304-G360 VanDerWaalsContact CD1-CA 3.42Å; W304-Y363 AromaticContact CH2-CD2 3.14Å; W304-Y363 HydrophobicContact CH2-CD2 3.14Å; W304-Y363 AromaticContact CH2-CE2 3.55Å; W304-Y363 HydrophobicContact CH2-CE2 3.55Å; W304-Y363 AromaticContact CH2-CG 3.84Å; W304-Y363 HydrophobicContact CH2-CG 3.84Å; W304-Y363 AromaticContact CZ2-CD2 3.38Å; W304-Y363 HydrophobicContact CZ2-CD2 3.38Å; W304-Y363 HydrophobicContact CZ2-CE2 4.24Å; W304-Y363 AromaticContact CZ2-CG 3.68Å; W304-Y363 HydrophobicContact CZ2-CG 3.68Å; W304-Y363 HydrophobicContact CZ3-CD2 4.05Å; W304-Y363 HydrophobicContact CZ3-CE2 4.25Å
305I94.7Very high94.8Very high44 Ų4442.1 Ų42.123%0.22621%0.208CC..Hα-helixtrans-62.1-46.9178.6-59.8167.1000110.4S137 S301 V302 A303 L307 N308 F309S137-I305 VanDerWaalsContact CB-CD1 3.4Å; S137-I305 WeakPolarHBondContact OG-CD1 3.28Å; S137-I305 WeakPolarHBondContact OG-CG1 3.42Å; S301-I305 VanDerWaalsContact O-CG1 3.3Å; S301-I305 WeakPolarHBondContact O-CG1 3.27Å; S301-I305 PolarHBondContact O-N 3.06Å; V302-I305 PolarHBondContact O-N 3.48Å; A303-I305 PolarHBondContact O-N 3.49Å; I305-L307 VanDerWaalsContact C-N 3.3Å; I305-L307 PolarHBondContact O-N 2.91Å; I305-N308 WeakPolarHBondContact O-CB 3.21Å; I305-N308 PolarHBondContact O-N 3.39Å; I305-N308 VanDerWaalsContact O-N 3.07Å; I305-F309 HydrophobicContact CG2-CD2 3.72Å; I305-F309 HydrophobicContact CG2-CE2 3.58Å; I305-F309 HydrophobicContact CG2-CZ 4.48Å; I305-F309 VanDerWaalsContact O-CD2 3.32Å; I305-F309 WeakPolarHBondContact O-CD2 3.28Å; I305-F309 PolarHBondContact O-N 3.45Å
306T96.6Very high95Very high72 Ų7241.8 Ų41.844%0.44222%0.219SC..Hα-helixtrans-59.2-43.3-175.3-60.60000111.4V302 A303 F309 N310V302-T306 VanDerWaalsContact O-CB 3.28Å; V302-T306 WeakPolarHBondContact O-CB 3.31Å; V302-T306 PolarHBondContact O-N 3.28Å; V302-T306 PolarHBondContact O-OG1 3.46Å; A303-T306 PolarHBondContact O-N 3.26Å; T306-F309 PolarHBondContact O-N 3.03Å; T306-N310 PolarHBondContact O-N 3.34Å; T306-N310 PolarHBondContact O-ND2 3.28Å
307L97Very high95.1Very high26 Ų2650 Ų5014%0.13625%0.254CS..Hα-helixtrans-60.4-47.6174.7-17488.2000111.4A303 I305 F309 N310 L311 I314 L357 Y361A303-L307 WeakPolarHBondContact O-CB 3.34Å; A303-L307 PolarHBondContact O-N 2.96Å; I305-L307 VanDerWaalsContact C-N 3.3Å; I305-L307 PolarHBondContact O-N 2.91Å; L307-F309 VanDerWaalsContact C-N 3.27Å; L307-F309 PolarHBondContact O-N 3.48Å; L307-N310 CarbonylContact O-C 3.39Å; L307-N310 WeakPolarHBondContact O-CA 3.37Å; L307-N310 PolarHBondContact O-N 3.21Å; L307-L311 PolarHBondContact O-N 3.4Å; L307-I314 HydrophobicContact CD1-CD1 3.79Å; L307-I314 HydrophobicContact CG-CD1 4.43Å; L307-L357 HydrophobicContact CB-CD2 3.92Å; L307-L357 HydrophobicContact CD1-CB 4.45Å; L307-L357 HydrophobicContact CD1-CD2 3.97Å; L307-L357 WeakPolarHBondContact CD2-O 3.15Å; L307-Y361 VanDerWaalsContact CD2-CA 3.47Å; L307-Y361 VanDerWaalsContact CD2-CB 3.48Å
308N96Very high95.4Very high0 Ų053.1 Ų53.10%027%0.27CS..Hα-helixtrans-61.2-35.3-178.1-86.3-73.8000113.4Y129 W304 I305 N310 L311 G360 T364Y129-N308 PolarHBondContact O-OD1 2.94Å; W304-N308 PolarHBondContact O-N 3.14Å; W304-N308 PolarHBondContact O-ND2 2.91Å; I305-N308 WeakPolarHBondContact O-CB 3.21Å; I305-N308 PolarHBondContact O-N 3.39Å; I305-N308 VanDerWaalsContact O-N 3.07Å; N308-N310 PolarHBondContact O-N 2.92Å; N308-L311 WeakPolarHBondContact O-CB 3.43Å; N308-L311 PolarHBondContact O-N 3.49Å; N308-G360 WeakPolarHBondContact ND2-CA 3.47Å; N308-G360 PolarHBondContact ND2-O 3.22Å; N308-G360 PolarHBondContact OD1-O 3.01Å; N308-T364 WeakPolarHBondContact OD1-CB 3.47Å; N308-T364 VanDerWaalsContact OD1-CG2 3.25Å; N308-T364 WeakPolarHBondContact OD1-CG2 3.32Å; N308-T364 PolarHBondContact OD1-OG1 3.01Å
309F96.8Very high95.5Very high82 Ų8251.3 Ų51.336%0.3627%0.267SS..Hα-helixtrans-66.7-28.8174.8-87.5-121.1000113.2K130 I134 I305 T306 L307 H312K130-F309 HydrophobicContact CB-CD2 4.11Å; K130-F309 HydrophobicContact CB-CE2 3.89Å; K130-F309 HydrophobicContact CB-CZ 4.15Å; K130-F309 HydrophobicContact CD-CD1 4.14Å; K130-F309 HydrophobicContact CD-CE1 4.22Å; K130-F309 HydrophobicContact CD-CG 4.44Å; K130-F309 HydrophobicContact CG-CD1 4.29Å; K130-F309 HydrophobicContact CG-CD2 4.1Å; K130-F309 HydrophobicContact CG-CE1 4.48Å; K130-F309 HydrophobicContact CG-CE2 4.29Å; K130-F309 HydrophobicContact CG-CG 4.1Å; K130-F309 HydrophobicContact CG-CZ 4.49Å; I134-F309 HydrophobicContact CD1-CE2 4.18Å; I134-F309 HydrophobicContact CD1-CZ 4.08Å; I134-F309 HydrophobicContact CG1-CE2 3.97Å; I134-F309 HydrophobicContact CG1-CZ 4.29Å; I305-F309 HydrophobicContact CG2-CD2 3.72Å; I305-F309 HydrophobicContact CG2-CE2 3.58Å; I305-F309 HydrophobicContact CG2-CZ 4.48Å; I305-F309 VanDerWaalsContact O-CD2 3.32Å; I305-F309 WeakPolarHBondContact O-CD2 3.28Å; I305-F309 PolarHBondContact O-N 3.45Å; T306-F309 PolarHBondContact O-N 3.03Å; L307-F309 VanDerWaalsContact C-N 3.27Å; L307-F309 PolarHBondContact O-N 3.48Å; F309-H312 PolarHBondContact O-CE1 3.12Å; F309-H312 PolarHBondContact O-ND1 3.27Å
310N97.1Very high95.5Very high55 Ų5553.1 Ų53.129%0.29427%0.27SS..Hα-helixtrans-99.9-2.2-179.8-68.8-74.7000113.2T306 L307 N308 H312 R313 I314T306-N310 PolarHBondContact O-N 3.34Å; T306-N310 PolarHBondContact O-ND2 3.28Å; L307-N310 CarbonylContact O-C 3.39Å; L307-N310 WeakPolarHBondContact O-CA 3.37Å; L307-N310 PolarHBondContact O-N 3.21Å; N308-N310 PolarHBondContact O-N 2.92Å; N310-H312 VanDerWaalsContact C-N 3.33Å; N310-H312 PolarHBondContact O-N 3.37Å; N310-R313 WeakPolarHBondContact O-CA 3.41Å; N310-R313 WeakPolarHBondContact O-CB 3.44Å; N310-R313 PolarHBondContact O-N 3.41Å; N310-R313 PolarHBondContact OD1-NH1 3.45Å; N310-I314 HydrophobicContact CB-CD1 4.43Å; N310-I314 WeakPolarHBondContact O-CG1 3.42Å; N310-I314 PolarHBondContact O-N 3.17Å; N310-I314 VanDerWaalsContact O-N 3.11Å
311L95.7Very high95.6Very high0 Ų055.3 Ų55.30%028%0.279CS..Hα-helixtrans-56.1-43.6-171.2-177.553.1000113.1Y129 L307 N308 R313 I314 E315 Y361 T364Y129-L311 HydrophobicContact CD1-CD2 4.21Å; Y129-L311 HydrophobicContact CD2-CB 3.86Å; Y129-L311 HydrophobicContact CD2-CD2 3.89Å; Y129-L311 HydrophobicContact CD2-CG 3.8Å; Y129-L311 HydrophobicContact CE2-CB 4.46Å; Y129-L311 HydrophobicContact CE2-CD2 4.2Å; Y129-L311 HydrophobicContact CE2-CG 3.99Å; Y129-L311 HydrophobicContact CG-CB 4.36Å; Y129-L311 HydrophobicContact CG-CD2 3.87Å; Y129-L311 HydrophobicContact CG-CG 4.28Å; L307-L311 PolarHBondContact O-N 3.4Å; N308-L311 WeakPolarHBondContact O-CB 3.43Å; N308-L311 PolarHBondContact O-N 3.49Å; L311-R313 VanDerWaalsContact C-N 3.26Å; L311-R313 PolarHBondContact O-N 2.9Å; L311-I314 WeakPolarHBondContact O-CB 3.48Å; L311-I314 PolarHBondContact O-N 3.23Å; L311-I314 VanDerWaalsContact O-N 3.1Å; L311-E315 HydrophobicContact CD1-CG 4.08Å; L311-E315 HydrophobicContact CG-CG 4.43Å; L311-E315 WeakPolarHBondContact O-CG 3.3Å; L311-E315 PolarHBondContact O-N 2.82Å; L311-Y361 HydrophobicContact CD1-CD2 3.45Å; L311-Y361 VanDerWaalsContact CD1-CD2 3.45Å; L311-Y361 HydrophobicContact CD1-CE2 3.73Å; L311-T364 HydrophobicContact CD2-CG2 3.83Å
312H95.9Very high95.8Very high62 Ų6258 Ų5829%0.28730%0.296SS..Hα-helixtrans-59.5-33.8176.270.7-75.3000113.7P126 Y129 F309 N310 A316P126-H312 HydrophobicContact CB-CB 3.54Å; P126-H312 HydrophobicContact CG-CB 4.43Å; Y129-H312 HydrophobicContact CD2-CB 4.33Å; Y129-H312 HydrophobicContact CE2-CB 4.41Å; F309-H312 PolarHBondContact O-CE1 3.12Å; F309-H312 PolarHBondContact O-ND1 3.27Å; N310-H312 VanDerWaalsContact C-N 3.33Å; N310-H312 PolarHBondContact O-N 3.37Å; H312-A316 WeakPolarHBondContact O-CB 3.23Å; H312-A316 PolarHBondContact O-N 3.02Å; H312-A316 VanDerWaalsContact O-N 3.13Å
313R96.6Very high95.8Very high155 Ų15555.5 Ų55.559%0.58528%0.28SS*.Hα-helixtrans-75.5-33.7177.2-57.4179.8176.2170.3-10.3111.5N310 L311N310-R313 WeakPolarHBondContact O-CA 3.41Å; N310-R313 WeakPolarHBondContact O-CB 3.44Å; N310-R313 PolarHBondContact O-N 3.41Å; N310-R313 PolarHBondContact OD1-NH1 3.45Å; L311-R313 VanDerWaalsContact C-N 3.26Å; L311-R313 PolarHBondContact O-N 2.9Å
314I96Very high95.8Very high44 Ų4455.2 Ų55.223%0.22628%0.278CS..Hα-helixtrans-68.4-48.2176.3-61.7170.4000109L307 N310 L311 A316 K317 L318 I323L307-I314 HydrophobicContact CD1-CD1 3.79Å; L307-I314 HydrophobicContact CG-CD1 4.43Å; N310-I314 HydrophobicContact CB-CD1 4.43Å; N310-I314 WeakPolarHBondContact O-CG1 3.42Å; N310-I314 PolarHBondContact O-N 3.17Å; N310-I314 VanDerWaalsContact O-N 3.11Å; L311-I314 WeakPolarHBondContact O-CB 3.48Å; L311-I314 PolarHBondContact O-N 3.23Å; L311-I314 VanDerWaalsContact O-N 3.1Å; I314-A316 PolarHBondContact O-N 3.17Å; I314-K317 PolarHBondContact O-N 2.89Å; I314-L318 HydrophobicContact CG2-CD1 4Å; I314-L318 PolarHBondContact O-N 3.22Å; I314-I323 HydrophobicContact CG2-CD1 3.92Å; I314-I323 HydrophobicContact CG2-CG1 4.04Å; I314-I323 HydrophobicContact CG2-CG2 4.36Å
315E94.9Very high96Very high52 Ų5257 Ų5724%0.24329%0.288CS..Hα-helixtrans-65.1-25.3177.4-69.7-169.2148.300113.5Y129 L311 K317 I323 K365Y129-E315 VanDerWaalsContact CE2-OE2 3.29Å; Y129-E315 WeakPolarHBondContact CE2-OE2 3.42Å; Y129-E315 PolarHBondContact OH-OE2 3.02Å; L311-E315 HydrophobicContact CD1-CG 4.08Å; L311-E315 HydrophobicContact CG-CG 4.43Å; L311-E315 WeakPolarHBondContact O-CG 3.3Å; L311-E315 PolarHBondContact O-N 2.82Å; E315-K317 PolarHBondContact O-N 3.12Å; E315-I323 HydrophobicContact CG-CD1 3.95Å; E315-K365 VanDerWaalsContact OE1-CD 3.29Å; E315-K365 WeakPolarHBondContact OE1-CD 3.25Å; E315-K365 WeakPolarHBondContact OE1-CE 3.41Å; E315-K365 IonicContact OE1-NZ 3.7Å; E315-K365 PolarHBondContact OE1-NZ 3.43Å; E315-K365 IonicContact OE2-NZ 2.72Å
316A95.9Very high96.1Very high86 Ų8658.9 Ų58.971%0.71130%0.298SS*.THydrogen-bonded Turntrans-68.8-15.7172.800000113.3H312 I314H312-A316 WeakPolarHBondContact O-CB 3.23Å; H312-A316 PolarHBondContact O-N 3.02Å; H312-A316 VanDerWaalsContact O-N 3.13Å; I314-A316 PolarHBondContact O-N 3.17Å
317K95.9Very high96.2Very high185 Ų18555.7 Ų55.780%0.80428%0.278SS*.THydrogen-bonded Turntrans-120.2-28.3-174.4-65.3-175.6178.4-173.40114I314 E315I314-K317 PolarHBondContact O-N 2.89Å; E315-K317 PolarHBondContact O-N 3.12Å
318L95Very high96.3Very high68 Ų6854.4 Ų54.436%0.35627%0.272SS..SBendtrans-120141.8-173.9-61.2-179.5000110.5I314 V322 I323 L326I314-L318 HydrophobicContact CG2-CD1 4Å; I314-L318 PolarHBondContact O-N 3.22Å; L318-V322 HydrophobicContact CB-CG1 4.45Å; L318-V322 HydrophobicContact CD1-CG1 4.5Å; L318-V322 HydrophobicContact CD2-CG1 4.2Å; L318-I323 HydrophobicContact CB-CD1 3.98Å; L318-I323 HydrophobicContact CB-CG1 3.55Å; L318-I323 HydrophobicContact CD1-CG1 4.18Å; L318-L326 HydrophobicContact CD1-CD1 3.88Å
319S94.9Very high96.4Very high40 Ų4057.3 Ų57.328%0.2829%0.289SS..  trans-71.1158175.596.20000111.1K321 V322 I323 E440S319-K321 VanDerWaalsContact C-N 3.26Å; S319-K321 PolarHBondContact O-N 2.93Å; S319-V322 PolarHBondContact O-N 3.32Å; S319-V322 VanDerWaalsContact O-N 3.15Å; S319-V322 PolarHBondContact OG-N 3.03Å; S319-I323 WeakPolarHBondContact O-CG1 3.21Å; S319-I323 PolarHBondContact O-N 3.1Å; S319-I323 VanDerWaalsContact O-N 3.12Å; S319-E440 WeakPolarHBondContact CB-OE1 3.48Å; S319-E440 WeakPolarHBondContact CB-OE2 3.44Å; S319-E440 PolarHBondContact OG-OE1 3.13Å; S319-E440 PolarHBondContact OG-OE2 3.11Å
320R93.9Very high96.4Very high66 Ų6655.8 Ų55.825%0.24929%0.285CS..Hα-helixtrans-56.5-46.2-178.3-176.3-171.4-60.8-170.9-1.6110.2S256 V322 I323 Y324 Y361 E373 W434 F438 E440S256-R320 PolarHBondContact OG-NH1 3.48Å; R320-V322 VanDerWaalsContact C-N 3.32Å; R320-V322 PolarHBondContact O-N 3.29Å; R320-I323 PolarHBondContact O-N 2.98Å; R320-Y324 HydrophobicContact CG-CD2 3.88Å; R320-Y324 HydrophobicContact CG-CE2 3.77Å; R320-Y324 WeakPolarHBondContact O-CD2 3.45Å; R320-Y324 PolarHBondContact O-N 3.33Å; R320-Y324 VanDerWaalsContact O-N 3.16Å; R320-Y361 PolarHBondContact O-OH 2.9Å; R320-E373 IonicContact CZ-OE1 3.93Å; R320-E373 VanDerWaalsContact CZ-OE1 3.23Å; R320-E373 IonicContact NH1-OE1 2.67Å; R320-E373 PolarHBondContact NH1-OE1 3.43Å; R320-E373 IonicContact NH1-OE2 2.68Å; R320-E373 IonicContact NH2-OE1 2.98Å; R320-E373 PolarHBondContact NH2-OE1 3.44Å; R320-W434 HydrophobicContact CG-CZ3 4.49Å; R320-F438 HydrophobicContact CG-CZ 4.41Å; R320-E440 PolarHBondContact N-OE1 3.5Å
321K94.9Very high96.4Very high48 Ų4853.2 Ų53.221%0.20927%0.271CS..Hα-helixtrans-57.9-46.8-179.7-170.7173.2-175160.10110.9S319 I323 Y324 L325 W434 V435 F438S319-K321 VanDerWaalsContact C-N 3.26Å; S319-K321 PolarHBondContact O-N 2.93Å; K321-I323 VanDerWaalsContact C-N 3.34Å; K321-I323 PolarHBondContact O-N 3.47Å; K321-Y324 PolarHBondContact O-N 3.47Å; K321-L325 HydrophobicContact CG-CD1 4.22Å; K321-L325 VanDerWaalsContact O-CG 3.31Å; K321-L325 WeakPolarHBondContact O-CG 3.45Å; K321-L325 PolarHBondContact O-N 2.81Å; K321-L325 VanDerWaalsContact O-N 3.09Å; K321-W434 WeakPolarHBondContact CE-O 2.92Å; K321-V435 PolarHBondContact NZ-O 3.06Å; K321-F438 HydrophobicContact CB-CD1 3.82Å; K321-F438 HydrophobicContact CB-CE1 4.11Å; K321-F438 HydrophobicContact CD-CD1 4.19Å; K321-F438 HydrophobicContact CG-CD1 4.06Å; K321-F438 PolarHBondContact NZ-O 3.2Å
322V96.4Very high96.5Very high60 Ų6054.5 Ų54.536%0.36428%0.278SS..Hα-helixtrans-60.7-43.5-179174.40000111.2L318 S319 R320 L325 L326L318-V322 HydrophobicContact CB-CG1 4.45Å; L318-V322 HydrophobicContact CD1-CG1 4.5Å; L318-V322 HydrophobicContact CD2-CG1 4.2Å; S319-V322 PolarHBondContact O-N 3.32Å; S319-V322 VanDerWaalsContact O-N 3.15Å; S319-V322 PolarHBondContact OG-N 3.03Å; R320-V322 VanDerWaalsContact C-N 3.32Å; R320-V322 PolarHBondContact O-N 3.29Å; V322-L325 PolarHBondContact O-N 3.4Å; V322-L326 HydrophobicContact CG1-CD1 3.96Å; V322-L326 HydrophobicContact CG1-CG 4.36Å; V322-L326 WeakPolarHBondContact O-CG 3.26Å; V322-L326 PolarHBondContact O-N 3.47Å
323I96.1Very high96.6Very high10 Ų1054.2 Ų54.25%0.05128%0.28CS..Hα-helixtrans-69.6-37.4-177.1-51.5161.7000111.8I314 E315 L318 S319 R320 K321 L326 S327 Y361I314-I323 HydrophobicContact CG2-CD1 3.92Å; I314-I323 HydrophobicContact CG2-CG1 4.04Å; I314-I323 HydrophobicContact CG2-CG2 4.36Å; E315-I323 HydrophobicContact CG-CD1 3.95Å; L318-I323 HydrophobicContact CB-CD1 3.98Å; L318-I323 HydrophobicContact CB-CG1 3.55Å; L318-I323 HydrophobicContact CD1-CG1 4.18Å; S319-I323 WeakPolarHBondContact O-CG1 3.21Å; S319-I323 PolarHBondContact O-N 3.1Å; S319-I323 VanDerWaalsContact O-N 3.12Å; R320-I323 PolarHBondContact O-N 2.98Å; K321-I323 VanDerWaalsContact C-N 3.34Å; K321-I323 PolarHBondContact O-N 3.47Å; I323-L326 PolarHBondContact O-N 2.82Å; I323-S327 WeakPolarHBondContact O-CB 3.2Å; I323-S327 PolarHBondContact O-N 3.21Å; I323-S327 PolarHBondContact O-OG 3.44Å; I323-Y361 HydrophobicContact CB-CD2 4.37Å; I323-Y361 HydrophobicContact CB-CE1 3.92Å; I323-Y361 HydrophobicContact CB-CE2 3.75Å; I323-Y361 VanDerWaalsContact CB-CZ 3.48Å; I323-Y361 HydrophobicContact CD1-CE2 4.04Å; I323-Y361 HydrophobicContact CG1-CE2 4.5Å; I323-Y361 HydrophobicContact CG2-CD1 3.79Å; I323-Y361 HydrophobicContact CG2-CD2 3.34Å; I323-Y361 HydrophobicContact CG2-CE1 3.63Å; I323-Y361 HydrophobicContact CG2-CE2 3.19Å; I323-Y361 HydrophobicContact CG2-CG 3.63Å
324Y97.6Very high96.5Very high0 Ų046.9 Ų46.90%025%0.252CS..Hα-helixtrans-61.9-46.4172.7-87.1-78.7000111.7T263 R320 K321 L326 S327 F328 Y361 K365 D366 I369 W434T263-Y324 HydrophobicContact CG2-CE1 4.22Å; R320-Y324 HydrophobicContact CG-CD2 3.88Å; R320-Y324 HydrophobicContact CG-CE2 3.77Å; R320-Y324 WeakPolarHBondContact O-CD2 3.45Å; R320-Y324 PolarHBondContact O-N 3.33Å; R320-Y324 VanDerWaalsContact O-N 3.16Å; K321-Y324 PolarHBondContact O-N 3.47Å; Y324-L326 VanDerWaalsContact C-N 3.34Å; Y324-L326 PolarHBondContact O-N 3.47Å; Y324-S327 WeakPolarHBondContact O-CB 3.21Å; Y324-S327 PolarHBondContact O-N 3.1Å; Y324-S327 VanDerWaalsContact O-N 3.14Å; Y324-F328 HydrophobicContact CD1-CE1 4.23Å; Y324-F328 HydrophobicContact CD1-CE2 4.15Å; Y324-F328 AromaticContact CD1-CZ 3.58Å; Y324-F328 HydrophobicContact CD1-CZ 3.58Å; Y324-F328 HydrophobicContact CE1-CZ 4.48Å; Y324-F328 HydrophobicContact CG-CE2 4.48Å; Y324-F328 HydrophobicContact CG-CZ 4.35Å; Y324-F328 WeakPolarHBondContact O-CD2 3.2Å; Y324-F328 VanDerWaalsContact O-CG 3.27Å; Y324-F328 WeakPolarHBondContact O-CG 3.49Å; Y324-F328 PolarHBondContact O-N 3.39Å; Y324-Y361 HydrophobicContact CD1-CD1 4.4Å; Y324-Y361 AromaticContact CD1-CE1 3.85Å; Y324-Y361 HydrophobicContact CD1-CE1 3.85Å; Y324-Y361 AromaticContact CD2-CE1 3.55Å; Y324-Y361 HydrophobicContact CD2-CE1 3.55Å; Y324-Y361 AromaticContact CD2-CZ 3.97Å; Y324-Y361 WeakPolarHBondContact CD2-OH 3.49Å; Y324-Y361 AromaticContact CE1-CE1 3.99Å; Y324-Y361 HydrophobicContact CE1-CE1 3.99Å; Y324-Y361 AromaticContact CE2-CE1 3.65Å; Y324-Y361 HydrophobicContact CE2-CE1 3.65Å; Y324-Y361 AromaticContact CE2-CZ 3.91Å; Y324-Y361 WeakPolarHBondContact CE2-OH 3.27Å; Y324-Y361 AromaticContact CG-CE1 3.65Å; Y324-Y361 HydrophobicContact CG-CE1 3.65Å; Y324-Y361 AromaticContact CZ-CE1 3.89Å; Y324-K365 HydrophobicContact CE2-CG 4.07Å; Y324-D366 VanDerWaalsContact CE1-OD1 3.26Å; Y324-D366 WeakPolarHBondContact CE1-OD1 3.42Å; Y324-D366 VanDerWaalsContact CZ-OD1 3.28Å; Y324-D366 PolarHBondContact OH-OD1 2.83Å; Y324-I369 HydrophobicContact CE2-CD1 4.21Å; Y324-I369 WeakPolarHBondContact OH-CD1 3.1Å; Y324-W434 HydrophobicContact CD1-CD2 4.35Å; Y324-W434 AromaticContact CD1-CE2 3.79Å; Y324-W434 AromaticContact CD1-CH2 3.92Å; Y324-W434 HydrophobicContact CD1-CH2 3.92Å; Y324-W434 AromaticContact CD1-CZ2 3.55Å; Y324-W434 HydrophobicContact CD1-CZ2 3.55Å; Y324-W434 HydrophobicContact CD1-CZ3 4.43Å; Y324-W434 HydrophobicContact CD2-CD2 4.43Å; Y324-W434 AromaticContact CD2-CE3 3.91Å; Y324-W434 HydrophobicContact CD2-CE3 3.91Å; Y324-W434 AromaticContact CD2-CH2 3.16Å; Y324-W434 HydrophobicContact CD2-CH2 3.16Å; Y324-W434 AromaticContact CD2-CZ2 3.73Å; Y324-W434 HydrophobicContact CD2-CZ2 3.73Å; Y324-W434 AromaticContact CD2-CZ3 3.26Å; Y324-W434 HydrophobicContact CD2-CZ3 3.26Å; Y324-W434 AromaticContact CE1-CH2 3.88Å; Y324-W434 HydrophobicContact CE1-CH2 3.88Å; Y324-W434 AromaticContact CE1-CZ2 3.5Å; Y324-W434 HydrophobicContact CE1-CZ2 3.5Å; Y324-W434 AromaticContact CE2-CH2 3.15Å; Y324-W434 HydrophobicContact CE2-CH2 3.15Å; Y324-W434 AromaticContact CE2-CZ2 3.73Å; Y324-W434 HydrophobicContact CE2-CZ2 3.73Å; Y324-W434 AromaticContact CE2-CZ3 3.72Å; Y324-W434 HydrophobicContact CE2-CZ3 3.72Å; Y324-W434 AromaticContact CG-CD2 3.99Å; Y324-W434 HydrophobicContact CG-CD2 3.99Å; Y324-W434 AromaticContact CG-CE2 3.85Å; Y324-W434 AromaticContact CG-CE3 3.87Å; Y324-W434 HydrophobicContact CG-CE3 3.87Å; Y324-W434 AromaticContact CG-CH2 3.57Å; Y324-W434 HydrophobicContact CG-CH2 3.57Å; Y324-W434 AromaticContact CG-CZ2 3.65Å; Y324-W434 HydrophobicContact CG-CZ2 3.65Å; Y324-W434 AromaticContact CG-CZ3 3.67Å; Y324-W434 HydrophobicContact CG-CZ3 3.67Å; Y324-W434 AromaticContact CZ-CH2 3.5Å; Y324-W434 AromaticContact CZ-CZ2 3.59Å
325L97.9Very high96.4Very high42 Ų4244.8 Ų44.822%0.2224%0.242CC..Hα-helixtrans-61.5-41.7178.3-65.6178.6000112.2K321 V322 T329 I431 W434 V435K321-L325 HydrophobicContact CG-CD1 4.22Å; K321-L325 VanDerWaalsContact O-CG 3.31Å; K321-L325 WeakPolarHBondContact O-CG 3.45Å; K321-L325 PolarHBondContact O-N 2.81Å; K321-L325 VanDerWaalsContact O-N 3.09Å; V322-L325 PolarHBondContact O-N 3.4Å; L325-T329 WeakPolarHBondContact O-CB 3.44Å; L325-T329 PolarHBondContact O-N 2.96Å; L325-T329 PolarHBondContact O-OG1 3.35Å; L325-I431 HydrophobicContact CD2-CB 4.47Å; L325-I431 HydrophobicContact CD2-CG2 4.13Å; L325-W434 HydrophobicContact CD2-CB 4.19Å; L325-V435 HydrophobicContact CD1-CG2 4.22Å; L325-V435 HydrophobicContact CD2-CG2 3.86Å
326L97.8Very high96.3Very high84 Ų8445.4 Ų45.444%0.4425%0.246SC..Hα-helixtrans-61.5-43.6173.4-73.7173.2000111.5L318 V322 I323 Y324 T329 L330L318-L326 HydrophobicContact CD1-CD1 3.88Å; V322-L326 HydrophobicContact CG1-CD1 3.96Å; V322-L326 HydrophobicContact CG1-CG 4.36Å; V322-L326 WeakPolarHBondContact O-CG 3.26Å; V322-L326 PolarHBondContact O-N 3.47Å; I323-L326 PolarHBondContact O-N 2.82Å; Y324-L326 VanDerWaalsContact C-N 3.34Å; Y324-L326 PolarHBondContact O-N 3.47Å; L326-T329 PolarHBondContact O-N 3.07Å; L326-L330 VanDerWaalsContact O-CG 3.31Å; L326-L330 WeakPolarHBondContact O-CG 3.33Å; L326-L330 PolarHBondContact O-N 3.14Å
327S97.8Very high96.2Very high4 Ų444 Ų443%0.02823%0.226CC..Hα-helixtrans-62-49.6179.5-56.90000111.2I323 Y324 T329 L330 L331 S358 Y361I323-S327 WeakPolarHBondContact O-CB 3.2Å; I323-S327 PolarHBondContact O-N 3.21Å; I323-S327 PolarHBondContact O-OG 3.44Å; Y324-S327 WeakPolarHBondContact O-CB 3.21Å; Y324-S327 PolarHBondContact O-N 3.1Å; Y324-S327 VanDerWaalsContact O-N 3.14Å; S327-T329 VanDerWaalsContact C-N 3.26Å; S327-T329 PolarHBondContact O-N 3.37Å; S327-L330 WeakPolarHBondContact O-CB 3.42Å; S327-L330 PolarHBondContact O-N 2.9Å; S327-L330 VanDerWaalsContact O-N 3.15Å; S327-L331 PolarHBondContact O-N 3.25Å; S327-S358 VanDerWaalsContact O-CB 3.22Å; S327-S358 WeakPolarHBondContact O-CB 3.35Å; S327-S358 PolarHBondContact O-OG 2.96Å; S327-Y361 WeakPolarHBondContact OG-CB 3.3Å; S327-Y361 WeakPolarHBondContact OG-CD1 3.29Å
328F98.4Very high95.9Very high0 Ų035.4 Ų35.40%019%0.189CC..Hα-helixtrans-63.4-33.7176.7-53.9-38.9000112.7T263 Y324 L331 L332 I362 L430 I431 W434T263-F328 HydrophobicContact CG2-CE1 3.74Å; T263-F328 HydrophobicContact CG2-CZ 3.66Å; Y324-F328 HydrophobicContact CD1-CE1 4.23Å; Y324-F328 HydrophobicContact CD1-CE2 4.15Å; Y324-F328 AromaticContact CD1-CZ 3.58Å; Y324-F328 HydrophobicContact CD1-CZ 3.58Å; Y324-F328 HydrophobicContact CE1-CZ 4.48Å; Y324-F328 HydrophobicContact CG-CE2 4.48Å; Y324-F328 HydrophobicContact CG-CZ 4.35Å; Y324-F328 WeakPolarHBondContact O-CD2 3.2Å; Y324-F328 VanDerWaalsContact O-CG 3.27Å; Y324-F328 WeakPolarHBondContact O-CG 3.49Å; Y324-F328 PolarHBondContact O-N 3.39Å; F328-L331 PolarHBondContact O-N 2.87Å; F328-L332 WeakPolarHBondContact O-CB 3.28Å; F328-L332 PolarHBondContact O-N 2.82Å; F328-I362 HydrophobicContact CD1-CD1 3.73Å; F328-I362 HydrophobicContact CE1-CD1 3.57Å; F328-I362 HydrophobicContact CE1-CG1 4.07Å; F328-L430 HydrophobicContact CD1-CB 3.93Å; F328-L430 HydrophobicContact CD1-CD1 3.9Å; F328-L430 HydrophobicContact CD2-CB 3.87Å; F328-L430 HydrophobicContact CE1-CB 3.96Å; F328-L430 HydrophobicContact CE1-CD1 3.76Å; F328-L430 HydrophobicContact CE1-CG 4.31Å; F328-L430 HydrophobicContact CE2-CB 3.9Å; F328-L430 HydrophobicContact CG-CB 3.89Å; F328-L430 HydrophobicContact CZ-CB 3.94Å; F328-L430 HydrophobicContact CZ-CD1 4.39Å; F328-L430 HydrophobicContact CZ-CD2 4.4Å; F328-L430 HydrophobicContact CZ-CG 4.48Å; F328-I431 HydrophobicContact CB-CD1 4.07Å; F328-I431 HydrophobicContact CB-CG1 3.53Å; F328-I431 HydrophobicContact CD2-CG1 4.14Å; F328-I431 HydrophobicContact CG-CG1 4.31Å; F328-W434 HydrophobicContact CE2-CB 4.22Å; F328-W434 AromaticContact CE2-CD1 3.35Å; F328-W434 HydrophobicContact CE2-CD2 4.28Å; F328-W434 AromaticContact CE2-CG 3.69Å; F328-W434 HydrophobicContact CE2-CG 3.69Å; F328-W434 AromaticContact CE2-NE1 3.71Å; F328-W434 AromaticContact CZ-CD1 3.68Å; F328-W434 HydrophobicContact CZ-CG 4.33Å; F328-W434 AromaticContact CZ-NE1 3.56Å
329T98.3Very high95.4Very high60 Ų6032.5 Ų32.537%0.36817%0.174SC..Hα-helixtrans-67.9-41175.1-60.70000111.1L325 L326 S327 L331 L332 V333L325-T329 WeakPolarHBondContact O-CB 3.44Å; L325-T329 PolarHBondContact O-N 2.96Å; L325-T329 PolarHBondContact O-OG1 3.35Å; L326-T329 PolarHBondContact O-N 3.07Å; S327-T329 VanDerWaalsContact C-N 3.26Å; S327-T329 PolarHBondContact O-N 3.37Å; T329-L331 VanDerWaalsContact C-N 3.32Å; T329-L331 PolarHBondContact O-N 3.42Å; T329-L332 PolarHBondContact O-N 3.22Å; T329-V333 HydrophobicContact CG2-CG2 4.23Å; T329-V333 WeakPolarHBondContact O-CB 3.46Å; T329-V333 VanDerWaalsContact O-CG2 3.23Å; T329-V333 WeakPolarHBondContact O-CG2 3.26Å; T329-V333 PolarHBondContact O-N 3.1Å
330L98.1Very high95Very high51 Ų5138.1 Ų38.127%0.26719%0.194SC..Hα-helixtrans-61.5-41.6174.1-71.2170.4000111.6L326 S327 S334 L354 L357L326-L330 VanDerWaalsContact O-CG 3.31Å; L326-L330 WeakPolarHBondContact O-CG 3.33Å; L326-L330 PolarHBondContact O-N 3.14Å; S327-L330 WeakPolarHBondContact O-CB 3.42Å; S327-L330 PolarHBondContact O-N 2.9Å; S327-L330 VanDerWaalsContact O-N 3.15Å; L330-S334 WeakPolarHBondContact O-CB 3.26Å; L330-S334 PolarHBondContact O-N 2.99Å; L330-S334 PolarHBondContact O-OG 3.38Å; L330-L354 HydrophobicContact CD2-CB 4.43Å; L330-L354 HydrophobicContact CD2-CD2 3.94Å; L330-L357 HydrophobicContact CD1-CB 3.97Å; L330-L357 HydrophobicContact CD1-CD1 4.48Å
331L97.2Very high94.3Very high0 Ų036.4 Ų36.40%020%0.197CC..Hα-helixtrans-64.1-45.2175.6-169.361.2000111.7C270 F274 S327 F328 T329 S334 S335 A355 F359 V423C270-L331 HydrophobicContact CB-CD2 4.16Å; F274-L331 HydrophobicContact CE2-CD1 3.63Å; F274-L331 HydrophobicContact CZ-CD1 3.82Å; S327-L331 PolarHBondContact O-N 3.25Å; F328-L331 PolarHBondContact O-N 2.87Å; T329-L331 VanDerWaalsContact C-N 3.32Å; T329-L331 PolarHBondContact O-N 3.42Å; L331-S334 PolarHBondContact O-N 3.42Å; L331-S334 PolarHBondContact O-OG 2.87Å; L331-S335 PolarHBondContact O-N 2.68Å; L331-S335 PolarHBondContact O-OG 3.36Å; L331-A355 HydrophobicContact CD1-CB 4.34Å; L331-F359 HydrophobicContact CD1-CE1 4.34Å; L331-F359 HydrophobicContact CD1-CE2 4.04Å; L331-F359 HydrophobicContact CD1-CZ 3.75Å; L331-V423 HydrophobicContact CD1-CG1 4.1Å; L331-V423 HydrophobicContact CD2-CG1 4.11Å; L331-V423 HydrophobicContact CG-CG1 3.8Å
332L97.6Very high93.8Very high27 Ų2735.9 Ų35.914%0.14120%0.196CC..Hα-helixtrans-58.6-51.4175.9177.460.4000111.5F328 T329 S334 S335 I336 A424 I428 I431F328-L332 WeakPolarHBondContact O-CB 3.28Å; F328-L332 PolarHBondContact O-N 2.82Å; T329-L332 PolarHBondContact O-N 3.22Å; L332-S334 VanDerWaalsContact C-N 3.33Å; L332-S334 PolarHBondContact O-N 2.81Å; L332-S335 PolarHBondContact O-N 3.42Å; L332-S335 VanDerWaalsContact O-N 3.16Å; L332-I336 HydrophobicContact CD1-CD1 3.76Å; L332-I336 HydrophobicContact CD1-CG1 4.19Å; L332-I336 HydrophobicContact CG-CD1 3.83Å; L332-I336 WeakPolarHBondContact O-CG1 3.33Å; L332-I336 PolarHBondContact O-N 3.47Å; L332-A424 HydrophobicContact CD1-CB 3.6Å; L332-I428 HydrophobicContact CD1-CD1 4.15Å; L332-I428 HydrophobicContact CD1-CG1 3.97Å; L332-I428 HydrophobicContact CD2-CG1 3.93Å; L332-I431 HydrophobicContact CD2-CD1 4.38Å
333V96.9Very high93.2Very high57 Ų5740.4 Ų40.435%0.34521%0.211SC..Hα-helixtrans-60.5-43.7179.1170.50000110.6T329 S335 I336 I337 L354T329-V333 HydrophobicContact CG2-CG2 4.23Å; T329-V333 WeakPolarHBondContact O-CB 3.46Å; T329-V333 VanDerWaalsContact O-CG2 3.23Å; T329-V333 WeakPolarHBondContact O-CG2 3.26Å; T329-V333 PolarHBondContact O-N 3.1Å; V333-S335 VanDerWaalsContact C-N 3.27Å; V333-S335 PolarHBondContact O-N 2.82Å; V333-I336 PolarHBondContact O-N 3.23Å; V333-I337 HydrophobicContact CG1-CD1 3.51Å; V333-I337 HydrophobicContact CG1-CG1 4.18Å; V333-I337 WeakPolarHBondContact O-CB 3.2Å; V333-I337 VanDerWaalsContact O-CG1 3.22Å; V333-I337 WeakPolarHBondContact O-CG1 3.47Å; V333-I337 PolarHBondContact O-N 3.06Å; V333-L354 HydrophobicContact CG1-CD1 3.91Å
334S95.7Very high92.9Very high0 Ų044.8 Ų44.80%023%0.234CC..Hα-helixtrans-59.3-40.2177.276.30000112.4L330 L331 L332 I338 V351L330-S334 WeakPolarHBondContact O-CB 3.26Å; L330-S334 PolarHBondContact O-N 2.99Å; L330-S334 PolarHBondContact O-OG 3.38Å; L331-S334 PolarHBondContact O-N 3.42Å; L331-S334 PolarHBondContact O-OG 2.87Å; L332-S334 VanDerWaalsContact C-N 3.33Å; L332-S334 PolarHBondContact O-N 2.81Å; S334-I338 WeakPolarHBondContact O-CG1 3.41Å; S334-I338 PolarHBondContact O-N 3.15Å; S334-V351 WeakPolarHBondContact O-CG1 3.44Å
335S93.7Very high92.6Very high0 Ų046.3 Ų46.30%024%0.244CC..Hα-helixtrans-70.6-43.4-179.2-51.90000111.4L331 L332 V333 S339 V423L331-S335 PolarHBondContact O-N 2.68Å; L331-S335 PolarHBondContact O-OG 3.36Å; L332-S335 PolarHBondContact O-N 3.42Å; L332-S335 VanDerWaalsContact O-N 3.16Å; V333-S335 VanDerWaalsContact C-N 3.27Å; V333-S335 PolarHBondContact O-N 2.82Å; S335-S339 WeakPolarHBondContact O-CB 3.46Å; S335-S339 PolarHBondContact O-N 3.28Å; S335-S339 PolarHBondContact O-OG 2.99Å; S335-V423 WeakPolarHBondContact OG-CG1 3.26Å
336I93.1Very high92.4Very high66 Ų6648.5 Ų48.534%0.33826%0.259SS..Hα-helixtrans-63.4-45.8177.8-70.4171.1000111L332 V333 I338 S339 F340L332-I336 HydrophobicContact CD1-CD1 3.76Å; L332-I336 HydrophobicContact CD1-CG1 4.19Å; L332-I336 HydrophobicContact CG-CD1 3.83Å; L332-I336 WeakPolarHBondContact O-CG1 3.33Å; L332-I336 PolarHBondContact O-N 3.47Å; V333-I336 PolarHBondContact O-N 3.23Å; I336-I338 PolarHBondContact O-N 3.18Å; I336-S339 WeakPolarHBondContact O-CB 3.36Å; I336-S339 PolarHBondContact O-N 3.07Å; I336-F340 HydrophobicContact CG2-CD2 3.98Å; I336-F340 HydrophobicContact CG2-CE2 3.47Å; I336-F340 VanDerWaalsContact CG2-CE2 3.47Å; I336-F340 HydrophobicContact CG2-CZ 4.46Å; I336-F340 WeakPolarHBondContact O-CD2 3.31Å; I336-F340 PolarHBondContact O-N 3.48Å
337I92.4Very high92.2Very high56 Ų5648.6 Ų48.629%0.28726%0.259SS..Hα-helixtrans-61.7-45.2-177.4-67.9169000110.9V333 S339 F340 I342 V351 L354V333-I337 HydrophobicContact CG1-CD1 3.51Å; V333-I337 HydrophobicContact CG1-CG1 4.18Å; V333-I337 WeakPolarHBondContact O-CB 3.2Å; V333-I337 VanDerWaalsContact O-CG1 3.22Å; V333-I337 WeakPolarHBondContact O-CG1 3.47Å; V333-I337 PolarHBondContact O-N 3.06Å; I337-S339 VanDerWaalsContact C-N 3.33Å; I337-F340 PolarHBondContact O-N 3.38Å; I337-I342 HydrophobicContact CG2-CD1 3.36Å; I337-I342 HydrophobicContact CG2-CG1 4.48Å; I337-V351 HydrophobicContact CB-CG1 4.1Å; I337-V351 HydrophobicContact CB-CG2 4.2Å; I337-V351 HydrophobicContact CG2-CB 4.49Å; I337-V351 HydrophobicContact CG2-CG1 4.21Å; I337-V351 HydrophobicContact CG2-CG2 3.43Å; I337-V351 VanDerWaalsContact CG2-CG2 3.43Å; I337-L354 HydrophobicContact CD1-CD1 4.17Å
338I89.6Confident92Very high5 Ų548.4 Ų48.43%0.02626%0.258CS..Hα-helixtrans-67.9-35.9177.8-60166.7000110.5I278 S334 I336 F340 G341 V351 L352 L416 L420I278-I338 HydrophobicContact CD1-CD1 4.37Å; S334-I338 WeakPolarHBondContact O-CG1 3.41Å; S334-I338 PolarHBondContact O-N 3.15Å; I336-I338 PolarHBondContact O-N 3.18Å; I338-F340 PolarHBondContact O-N 2.9Å; I338-F340 VanDerWaalsContact O-N 3.14Å; I338-G341 PolarHBondContact O-N 3.36Å; I338-V351 HydrophobicContact CD1-CB 4.47Å; I338-V351 HydrophobicContact CD1-CG1 3.96Å; I338-V351 HydrophobicContact CG1-CB 4.19Å; I338-V351 HydrophobicContact CG1-CG1 3.72Å; I338-L352 HydrophobicContact CD1-CD2 4.23Å; I338-L416 HydrophobicContact CG2-CD2 4.11Å; I338-L420 HydrophobicContact CB-CD1 3.46Å; I338-L420 VanDerWaalsContact CB-CD1 3.46Å; I338-L420 HydrophobicContact CD1-CD1 4.47Å; I338-L420 HydrophobicContact CG2-CD1 3.27Å
339S85.9Confident91.8Very high7 Ų749.1 Ų49.15%0.04926%0.264CS..Hα-helixtrans-62.6-15.6175.6-70.10000114.7S335 I336 I337 G341 H417 L420S335-S339 WeakPolarHBondContact O-CB 3.46Å; S335-S339 PolarHBondContact O-N 3.28Å; S335-S339 PolarHBondContact O-OG 2.99Å; I336-S339 WeakPolarHBondContact O-CB 3.36Å; I336-S339 PolarHBondContact O-N 3.07Å; I337-S339 VanDerWaalsContact C-N 3.33Å; S339-G341 PolarHBondContact O-N 3.23Å; S339-H417 PolarHBondContact O-CD2 3.18Å; S339-L420 WeakPolarHBondContact OG-CB 3.46Å
340F85.3Confident91.6Very high158 Ų15852.7 Ų52.769%0.69327%0.274SS*.THydrogen-bonded Turntrans-79.38.9170.4-77.7-66.9000113.8I336 I337 I338I336-F340 HydrophobicContact CG2-CD2 3.98Å; I336-F340 HydrophobicContact CG2-CE2 3.47Å; I336-F340 VanDerWaalsContact CG2-CE2 3.47Å; I336-F340 HydrophobicContact CG2-CZ 4.46Å; I336-F340 WeakPolarHBondContact O-CD2 3.31Å; I336-F340 PolarHBondContact O-N 3.48Å; I337-F340 PolarHBondContact O-N 3.38Å; I338-F340 PolarHBondContact O-N 2.9Å; I338-F340 VanDerWaalsContact O-N 3.14Å
341G80.2Confident91.5Very high30 Ų3050.8 Ų50.831%0.30927%0.265SS..THydrogen-bonded Turntrans79.835.617000000113.8I338 S339 K343I338-G341 PolarHBondContact O-N 3.36Å; S339-G341 PolarHBondContact O-N 3.23Å; G341-K343 WeakPolarHBondContact O-CG 3.28Å; G341-K343 PolarHBondContact O-N 2.94Å; G341-K343 VanDerWaalsContact O-N 3.12Å
342I83.4Confident91.4Very high36 Ų3650.9 Ų50.919%0.18527%0.265CS..  trans-60.3116.4171.8-64.2-174.5000109.1I337 L347 I348 V351I337-I342 HydrophobicContact CG2-CD1 3.36Å; I337-I342 HydrophobicContact CG2-CG1 4.48Å; I342-L347 HydrophobicContact CD1-CB 4.42Å; I342-L347 HydrophobicContact CG2-CB 3.42Å; I342-L347 VanDerWaalsContact CG2-CB 3.42Å; I342-L347 HydrophobicContact CG2-CD1 4.11Å; I342-L347 HydrophobicContact CG2-CG 4.41Å; I342-I348 HydrophobicContact CB-CG1 4.47Å; I342-I348 HydrophobicContact CG2-CG1 3.94Å; I342-V351 HydrophobicContact CD1-CG2 4.29Å
343K83.4Confident91.4Very high155 Ų15552.3 Ų52.367%0.67427%0.272SS*.  trans-95.7-18177.9-59.6-173-178.6-1780113.7L286 G341 P345L286-K343 WeakPolarHBondContact CD1-O 3.43Å; L286-K343 HydrophobicContact CD2-CB 4.24Å; G341-K343 WeakPolarHBondContact O-CG 3.28Å; G341-K343 PolarHBondContact O-N 2.94Å; G341-K343 VanDerWaalsContact O-N 3.12Å; K343-P345 WeakPolarHBondContact O-CD 3.39Å
344L91.4Very high91.4Very high102 Ų10251.6 Ų51.653%0.53427%0.267SS..  trans-78.7118.1-176-168.364.3000110V346 L347 I348L344-V346 PolarHBondContact O-N 2.86Å; L344-V346 VanDerWaalsContact O-N 3.16Å; L344-L347 HydrophobicContact CB-CB 4.33Å; L344-L347 HydrophobicContact CB-CD1 4.02Å; L344-L347 HydrophobicContact CB-CG 4.17Å; L344-L347 HydrophobicContact CD2-CD1 4.17Å; L344-L347 HydrophobicContact CD2-CG 4.08Å; L344-L347 PolarHBondContact O-N 3.49Å; L344-I348 PolarHBondContact O-N 3.46Å; L344-I348 VanDerWaalsContact O-N 3.16Å
345P91.2Very high91.4Very high33 Ų3351.6 Ų51.621%0.21427%0.267CS..Hα-helixtrans-58.1-35.1-174.3-27.436.2000113.8L286 L288 V296 K343 L347 I348 A349L286-P345 HydrophobicContact CD1-CG 4.34Å; L288-P345 HydrophobicContact CD1-CB 4.03Å; L288-P345 HydrophobicContact CD1-CG 3.87Å; L288-P345 HydrophobicContact CD2-CG 4.48Å; V296-P345 HydrophobicContact CG2-CB 3.74Å; K343-P345 WeakPolarHBondContact O-CD 3.39Å; P345-L347 VanDerWaalsContact C-N 3.35Å; P345-L347 PolarHBondContact O-N 3.5Å; P345-I348 PolarHBondContact O-N 2.9Å; P345-A349 WeakPolarHBondContact O-CB 3.27Å; P345-A349 PolarHBondContact O-N 3.22Å
346V92.4Very high91.5Very high88 Ų8851.6 Ų51.653%0.53327%0.267SS..Hα-helixtrans-63.8-39.6177.21760000111.6L344 A349 F350L344-V346 PolarHBondContact O-N 2.86Å; L344-V346 VanDerWaalsContact O-N 3.16Å; V346-A349 WeakPolarHBondContact O-CB 3.39Å; V346-A349 PolarHBondContact O-N 2.93Å; V346-F350 HydrophobicContact CG1-CD2 3.89Å; V346-F350 HydrophobicContact CG1-CE2 3.67Å; V346-F350 WeakPolarHBondContact O-CD2 3.46Å; V346-F350 PolarHBondContact O-N 3.24Å
347L93.3Very high91.7Very high85 Ų8550.6 Ų50.645%0.44526%0.262SS..Hα-helixtrans-69.3-39.6176.9-70.2176.7000111.2I342 L344 P345 A349 F350 V351I342-L347 HydrophobicContact CD1-CB 4.42Å; I342-L347 HydrophobicContact CG2-CB 3.42Å; I342-L347 VanDerWaalsContact CG2-CB 3.42Å; I342-L347 HydrophobicContact CG2-CD1 4.11Å; I342-L347 HydrophobicContact CG2-CG 4.41Å; L344-L347 HydrophobicContact CB-CB 4.33Å; L344-L347 HydrophobicContact CB-CD1 4.02Å; L344-L347 HydrophobicContact CB-CG 4.17Å; L344-L347 HydrophobicContact CD2-CD1 4.17Å; L344-L347 HydrophobicContact CD2-CG 4.08Å; L344-L347 PolarHBondContact O-N 3.49Å; P345-L347 VanDerWaalsContact C-N 3.35Å; P345-L347 PolarHBondContact O-N 3.5Å; L347-A349 VanDerWaalsContact C-N 3.28Å; L347-A349 PolarHBondContact O-N 3.38Å; L347-F350 PolarHBondContact O-N 2.92Å; L347-V351 VanDerWaalsContact O-CG2 3.29Å; L347-V351 WeakPolarHBondContact O-CG2 3.42Å; L347-V351 PolarHBondContact O-N 2.84Å
348I94.3Very high92Very high1 Ų148 Ų481%0.00525%0.248CC..Hα-helixtrans-57.4-47.1172.3-61173.1000109.5I278 L282 L286 V296 I342 L344 P345 F350 V351 L352I278-I348 HydrophobicContact CG2-CG2 4.45Å; L282-I348 HydrophobicContact CD2-CD1 3.66Å; L286-I348 HydrophobicContact CD1-CD1 4.02Å; V296-I348 HydrophobicContact CG1-CB 4.09Å; V296-I348 HydrophobicContact CG1-CG2 3.85Å; I342-I348 HydrophobicContact CB-CG1 4.47Å; I342-I348 HydrophobicContact CG2-CG1 3.94Å; L344-I348 PolarHBondContact O-N 3.46Å; L344-I348 VanDerWaalsContact O-N 3.16Å; P345-I348 PolarHBondContact O-N 2.9Å; I348-F350 VanDerWaalsContact C-N 3.33Å; I348-F350 PolarHBondContact O-N 3.34Å; I348-V351 PolarHBondContact O-N 3.09Å; I348-L352 HydrophobicContact CG2-CD1 4.17Å; I348-L352 HydrophobicContact CG2-CG 4.31Å; I348-L352 VanDerWaalsContact O-CG 3.32Å; I348-L352 WeakPolarHBondContact O-CG 3.25Å; I348-L352 PolarHBondContact O-N 3.24Å
349A94.3Very high92.2Very high15 Ų1547.7 Ų47.712%0.12425%0.247CC..Hα-helixtrans-58.2-41.5178.600000112.7V296 P299 P345 V346 L347 L352V296-A349 HydrophobicContact CG1-CB 4.18Å; V296-A349 WeakPolarHBondContact O-CA 3.17Å; V296-A349 WeakPolarHBondContact O-CB 3.08Å; P299-A349 HydrophobicContact CG-CB 4.14Å; P345-A349 WeakPolarHBondContact O-CB 3.27Å; P345-A349 PolarHBondContact O-N 3.22Å; V346-A349 WeakPolarHBondContact O-CB 3.39Å; V346-A349 PolarHBondContact O-N 2.93Å; L347-A349 VanDerWaalsContact C-N 3.28Å; L347-A349 PolarHBondContact O-N 3.38Å; A349-L352 PolarHBondContact O-N 3.21Å
350F94.9Very high92.7Very high134 Ų13447.4 Ų47.459%0.58825%0.245SC*.Hα-helixtrans-64.7-39.3173.7-84.6-67.7000112.8V346 L347 I348 L352 I353V346-F350 HydrophobicContact CG1-CD2 3.89Å; V346-F350 HydrophobicContact CG1-CE2 3.67Å; V346-F350 WeakPolarHBondContact O-CD2 3.46Å; V346-F350 PolarHBondContact O-N 3.24Å; L347-F350 PolarHBondContact O-N 2.92Å; I348-F350 VanDerWaalsContact C-N 3.33Å; I348-F350 PolarHBondContact O-N 3.34Å; F350-L352 VanDerWaalsContact C-N 3.31Å; F350-L352 PolarHBondContact O-N 2.86Å; F350-I353 HydrophobicContact CD1-CD1 3.99Å; F350-I353 VanDerWaalsContact O-CB 3.3Å; F350-I353 WeakPolarHBondContact O-CB 3.49Å; F350-I353 PolarHBondContact O-N 3.47Å
351V95.5Very high93.2Very high12 Ų1239.9 Ų39.97%0.07321%0.212CC..Hα-helixtrans-68.4-33.9178.1178.70000111.5S334 I337 I338 I342 L347 I348 I353 L354S334-V351 WeakPolarHBondContact O-CG1 3.44Å; I337-V351 HydrophobicContact CB-CG1 4.1Å; I337-V351 HydrophobicContact CB-CG2 4.2Å; I337-V351 HydrophobicContact CG2-CB 4.49Å; I337-V351 HydrophobicContact CG2-CG1 4.21Å; I337-V351 HydrophobicContact CG2-CG2 3.43Å; I337-V351 VanDerWaalsContact CG2-CG2 3.43Å; I338-V351 HydrophobicContact CD1-CB 4.47Å; I338-V351 HydrophobicContact CD1-CG1 3.96Å; I338-V351 HydrophobicContact CG1-CB 4.19Å; I338-V351 HydrophobicContact CG1-CG1 3.72Å; I342-V351 HydrophobicContact CD1-CG2 4.29Å; L347-V351 VanDerWaalsContact O-CG2 3.29Å; L347-V351 WeakPolarHBondContact O-CG2 3.42Å; L347-V351 PolarHBondContact O-N 2.84Å; I348-V351 PolarHBondContact O-N 3.09Å; V351-I353 PolarHBondContact O-N 2.79Å; V351-L354 WeakPolarHBondContact O-CB 3.48Å; V351-L354 PolarHBondContact O-N 3.49Å
352L95.2Very high94Very high1 Ų138.5 Ų38.51%0.00520%0.197CC..Hα-helixtrans-64.9-19.2176.3-70.3-177.2000114.1F274 I278 V296 I297 L300 I338 I348 A349 F350 L354 A355 G356F274-L352 HydrophobicContact CD1-CD2 3.52Å; F274-L352 HydrophobicContact CE1-CD2 3.85Å; I278-L352 HydrophobicContact CD1-CD2 3.6Å; I278-L352 HydrophobicContact CG2-CD1 4.39Å; V296-L352 HydrophobicContact CG1-CD1 4.45Å; V296-L352 WeakPolarHBondContact O-CD1 3.43Å; I297-L352 HydrophobicContact CB-CD1 4.39Å; I297-L352 HydrophobicContact CG1-CD1 4.11Å; L300-L352 HydrophobicContact CB-CB 4.29Å; L300-L352 HydrophobicContact CD1-CD2 4.4Å; I338-L352 HydrophobicContact CD1-CD2 4.23Å; I348-L352 HydrophobicContact CG2-CD1 4.17Å; I348-L352 HydrophobicContact CG2-CG 4.31Å; I348-L352 VanDerWaalsContact O-CG 3.32Å; I348-L352 WeakPolarHBondContact O-CG 3.25Å; I348-L352 PolarHBondContact O-N 3.24Å; A349-L352 PolarHBondContact O-N 3.21Å; F350-L352 VanDerWaalsContact C-N 3.31Å; F350-L352 PolarHBondContact O-N 2.86Å; L352-L354 VanDerWaalsContact C-N 3.28Å; L352-L354 PolarHBondContact O-N 3.39Å; L352-A355 PolarHBondContact O-N 3.47Å; L352-G356 PolarHBondContact O-N 3.18Å
353I96.6Very high94.4Very high57 Ų5737.3 Ų37.329%0.29219%0.19SC..Hα-helixtrans-59.6-42.6168.8-63.9174.6000110P299 A303 F350 V351 A355 G356 L357P299-I353 HydrophobicContact CB-CD1 4.43Å; P299-I353 HydrophobicContact CB-CG1 3.79Å; A303-I353 HydrophobicContact CB-CB 4.27Å; A303-I353 HydrophobicContact CB-CG2 3.81Å; A303-I353 WeakPolarHBondContact CB-O 3.35Å; F350-I353 HydrophobicContact CD1-CD1 3.99Å; F350-I353 VanDerWaalsContact O-CB 3.3Å; F350-I353 WeakPolarHBondContact O-CB 3.49Å; F350-I353 PolarHBondContact O-N 3.47Å; V351-I353 PolarHBondContact O-N 2.79Å; I353-A355 PolarHBondContact O-N 2.72Å; I353-G356 PolarHBondContact O-N 3.23Å; I353-L357 HydrophobicContact CG2-CD1 4.38Å; I353-L357 HydrophobicContact CG2-CG 4.44Å; I353-L357 WeakPolarHBondContact O-CG 3.21Å; I353-L357 PolarHBondContact O-N 3.47Å
354L97.5Very high95Very high43 Ų4330 Ų3023%0.22516%0.159CC..Hα-helixtrans-62.8-44.6179.9-54.7179.2000111.3L330 V333 I337 V351 L352 G356 L357 S358L330-L354 HydrophobicContact CD2-CB 4.43Å; L330-L354 HydrophobicContact CD2-CD2 3.94Å; V333-L354 HydrophobicContact CG1-CD1 3.91Å; I337-L354 HydrophobicContact CD1-CD1 4.17Å; V351-L354 WeakPolarHBondContact O-CB 3.48Å; V351-L354 PolarHBondContact O-N 3.49Å; L352-L354 VanDerWaalsContact C-N 3.28Å; L352-L354 PolarHBondContact O-N 3.39Å; L354-G356 VanDerWaalsContact C-N 3.34Å; L354-G356 PolarHBondContact O-N 2.98Å; L354-L357 PolarHBondContact O-N 3.41Å; L354-S358 PolarHBondContact O-N 2.64Å
355A96.3Very high95.2Very high0 Ų026.1 Ų26.10%014%0.137CC..Hα-helixtrans-62-43174.900000111.3F274 L300 L331 L352 I353 L357 S358 F359F274-A355 HydrophobicContact CD1-CB 3.94Å; F274-A355 HydrophobicContact CE1-CB 3.55Å; F274-A355 HydrophobicContact CZ-CB 3.99Å; L300-A355 HydrophobicContact CD1-CB 4.22Å; L331-A355 HydrophobicContact CD1-CB 4.34Å; L352-A355 PolarHBondContact O-N 3.47Å; I353-A355 PolarHBondContact O-N 2.72Å; A355-L357 PolarHBondContact O-N 3.2Å; A355-S358 WeakPolarHBondContact O-CB 3.48Å; A355-S358 PolarHBondContact O-N 3.39Å; A355-S358 VanDerWaalsContact O-N 3.16Å; A355-F359 HydrophobicContact CB-CD2 4.35Å; A355-F359 HydrophobicContact CB-CE2 4.1Å; A355-F359 WeakPolarHBondContact O-CD2 3.36Å; A355-F359 PolarHBondContact O-N 3.35Å
356G96.1Very high95.5Very high0 Ų024.5 Ų24.50%013%0.127CC..Hα-helixtrans-62.2-40.8177.200000113.7L300 W304 L352 I353 L354 G360L300-G356 VanDerWaalsContact O-CA 3.27Å; L300-G356 WeakPolarHBondContact O-CA 3.34Å; W304-G356 VanDerWaalsContact CA-O 3.3Å; W304-G356 WeakPolarHBondContact CA-O 3.41Å; L352-G356 PolarHBondContact O-N 3.18Å; I353-G356 PolarHBondContact O-N 3.23Å; L354-G356 VanDerWaalsContact C-N 3.34Å; L354-G356 PolarHBondContact O-N 2.98Å; G356-G360 PolarHBondContact O-N 3.13Å
357L97.4Very high95.7Very high45 Ų4520.3 Ų20.324%0.23610%0.102CC..Hα-helixtrans-62.1-42171.9-66.3177000111.2A303 L307 L330 I353 L354 A355 Y361A303-L357 HydrophobicContact CB-CD2 4.13Å; A303-L357 HydrophobicContact CB-CG 4.16Å; L307-L357 HydrophobicContact CB-CD2 3.92Å; L307-L357 HydrophobicContact CD1-CB 4.45Å; L307-L357 HydrophobicContact CD1-CD2 3.97Å; L307-L357 WeakPolarHBondContact CD2-O 3.15Å; L330-L357 HydrophobicContact CD1-CB 3.97Å; L330-L357 HydrophobicContact CD1-CD1 4.48Å; I353-L357 HydrophobicContact CG2-CD1 4.38Å; I353-L357 HydrophobicContact CG2-CG 4.44Å; I353-L357 WeakPolarHBondContact O-CG 3.21Å; I353-L357 PolarHBondContact O-N 3.47Å; L354-L357 PolarHBondContact O-N 3.41Å; A355-L357 PolarHBondContact O-N 3.2Å; L357-Y361 PolarHBondContact O-N 3.15Å
358S97.4Very high95.8Very high0 Ų016.4 Ų16.40%08%0.081CC..Hα-helixtrans-61.6-56.7176.1174.40000112S327 L354 A355 G360 Y361 I362S327-S358 VanDerWaalsContact O-CB 3.22Å; S327-S358 WeakPolarHBondContact O-CB 3.35Å; S327-S358 PolarHBondContact O-OG 2.96Å; L354-S358 PolarHBondContact O-N 2.64Å; A355-S358 WeakPolarHBondContact O-CB 3.48Å; A355-S358 PolarHBondContact O-N 3.39Å; A355-S358 VanDerWaalsContact O-N 3.16Å; S358-G360 PolarHBondContact O-N 3.37Å; S358-Y361 PolarHBondContact O-N 3.11Å; S358-I362 WeakPolarHBondContact O-CG1 3.08Å; S358-I362 PolarHBondContact O-N 2.93Å; S358-I362 VanDerWaalsContact O-N 3.13Å; S358-I362 WeakPolarHBondContact OG-CD1 3.3Å
359F95.2Very high95.9Very high0 Ų016.4 Ų16.40%08%0.081CC..Hα-helixtrans-59.4-38.2-178.8-69.4-54.8000111.8T267 C270 L271 F274 L300 W304 L331 A355 Y361 I362 Y363T267-F359 HydrophobicContact CG2-CD1 3.5Å; T267-F359 HydrophobicContact CG2-CE1 3.63Å; C270-F359 HydrophobicContact CB-CE1 4.33Å; C270-F359 HydrophobicContact CB-CZ 4.33Å; L271-F359 HydrophobicContact CB-CD1 4.42Å; L271-F359 HydrophobicContact CB-CE1 3.86Å; L271-F359 HydrophobicContact CB-CZ 4.06Å; L271-F359 HydrophobicContact CD1-CD1 4.12Å; L271-F359 HydrophobicContact CD1-CD2 3.83Å; L271-F359 HydrophobicContact CD1-CE1 4.09Å; L271-F359 HydrophobicContact CD1-CE2 3.79Å; L271-F359 HydrophobicContact CD1-CG 4.01Å; L271-F359 HydrophobicContact CD1-CZ 3.93Å; F274-F359 HydrophobicContact CB-CE2 4.48Å; F274-F359 AromaticContact CD2-CE2 3.91Å; F274-F359 HydrophobicContact CD2-CE2 3.91Å; F274-F359 AromaticContact CD2-CZ 3.83Å; F274-F359 HydrophobicContact CD2-CZ 3.83Å; F274-F359 HydrophobicContact CE2-CE2 4.33Å; F274-F359 HydrophobicContact CE2-CZ 4.18Å; F274-F359 HydrophobicContact CG-CE2 4.12Å; F274-F359 HydrophobicContact CG-CZ 4.46Å; L300-F359 HydrophobicContact CD1-CD2 4.34Å; L300-F359 HydrophobicContact CD1-CE2 4.39Å; W304-F359 HydrophobicContact CD2-CB 4.21Å; W304-F359 HydrophobicContact CE3-CB 3.65Å; W304-F359 HydrophobicContact CH2-CB 4.17Å; W304-F359 HydrophobicContact CZ3-CB 3.64Å; W304-F359 HydrophobicContact CZ3-CG 4.34Å; L331-F359 HydrophobicContact CD1-CE1 4.34Å; L331-F359 HydrophobicContact CD1-CE2 4.04Å; L331-F359 HydrophobicContact CD1-CZ 3.75Å; A355-F359 HydrophobicContact CB-CD2 4.35Å; A355-F359 HydrophobicContact CB-CE2 4.1Å; A355-F359 WeakPolarHBondContact O-CD2 3.36Å; A355-F359 PolarHBondContact O-N 3.35Å; F359-Y361 VanDerWaalsContact C-N 3.28Å; F359-Y361 PolarHBondContact O-N 2.78Å; F359-I362 PolarHBondContact O-N 3.21Å; F359-Y363 HydrophobicContact CB-CD2 4.08Å; F359-Y363 HydrophobicContact CB-CE2 4.33Å; F359-Y363 HydrophobicContact CD1-CD2 4.32Å; F359-Y363 AromaticContact CD1-CE2 3.85Å; F359-Y363 HydrophobicContact CD1-CE2 3.85Å; F359-Y363 HydrophobicContact CG-CE2 4.42Å; F359-Y363 WeakPolarHBondContact O-CB 3.43Å; F359-Y363 WeakPolarHBondContact O-CD2 3.5Å; F359-Y363 PolarHBondContact O-N 2.67Å
360G95.3Very high96Very high0 Ų015.7 Ų15.70%08%0.076CC..Hα-helixtrans-58.5-38.3178.900000113.8W304 N308 G356 S358 T364W304-G360 VanDerWaalsContact CD1-CA 3.42Å; N308-G360 WeakPolarHBondContact ND2-CA 3.47Å; N308-G360 PolarHBondContact ND2-O 3.22Å; N308-G360 PolarHBondContact OD1-O 3.01Å; G356-G360 PolarHBondContact O-N 3.13Å; S358-G360 PolarHBondContact O-N 3.37Å; G360-T364 PolarHBondContact O-OG1 3.12Å
361Y95.4Very high96Very high1 Ų19.4 Ų9.40%0.0045%0.048CC..Hα-helixtrans-77.9-53.7179.5174.1-103.8000109.9L307 L311 R320 I323 Y324 S327 L357 S358 F359 Y363 T364 K365L307-Y361 VanDerWaalsContact CD2-CA 3.47Å; L307-Y361 VanDerWaalsContact CD2-CB 3.48Å; L311-Y361 HydrophobicContact CD1-CD2 3.45Å; L311-Y361 VanDerWaalsContact CD1-CD2 3.45Å; L311-Y361 HydrophobicContact CD1-CE2 3.73Å; R320-Y361 PolarHBondContact O-OH 2.9Å; I323-Y361 HydrophobicContact CB-CD2 4.37Å; I323-Y361 HydrophobicContact CB-CE1 3.92Å; I323-Y361 HydrophobicContact CB-CE2 3.75Å; I323-Y361 VanDerWaalsContact CB-CZ 3.48Å; I323-Y361 HydrophobicContact CD1-CE2 4.04Å; I323-Y361 HydrophobicContact CG1-CE2 4.5Å; I323-Y361 HydrophobicContact CG2-CD1 3.79Å; I323-Y361 HydrophobicContact CG2-CD2 3.34Å; I323-Y361 HydrophobicContact CG2-CE1 3.63Å; I323-Y361 HydrophobicContact CG2-CE2 3.19Å; I323-Y361 HydrophobicContact CG2-CG 3.63Å; Y324-Y361 HydrophobicContact CD1-CD1 4.4Å; Y324-Y361 AromaticContact CD1-CE1 3.85Å; Y324-Y361 HydrophobicContact CD1-CE1 3.85Å; Y324-Y361 AromaticContact CD2-CE1 3.55Å; Y324-Y361 HydrophobicContact CD2-CE1 3.55Å; Y324-Y361 AromaticContact CD2-CZ 3.97Å; Y324-Y361 WeakPolarHBondContact CD2-OH 3.49Å; Y324-Y361 AromaticContact CE1-CE1 3.99Å; Y324-Y361 HydrophobicContact CE1-CE1 3.99Å; Y324-Y361 AromaticContact CE2-CE1 3.65Å; Y324-Y361 HydrophobicContact CE2-CE1 3.65Å; Y324-Y361 AromaticContact CE2-CZ 3.91Å; Y324-Y361 WeakPolarHBondContact CE2-OH 3.27Å; Y324-Y361 AromaticContact CG-CE1 3.65Å; Y324-Y361 HydrophobicContact CG-CE1 3.65Å; Y324-Y361 AromaticContact CZ-CE1 3.89Å; S327-Y361 WeakPolarHBondContact OG-CB 3.3Å; S327-Y361 WeakPolarHBondContact OG-CD1 3.29Å; L357-Y361 PolarHBondContact O-N 3.15Å; S358-Y361 PolarHBondContact O-N 3.11Å; F359-Y361 VanDerWaalsContact C-N 3.28Å; F359-Y361 PolarHBondContact O-N 2.78Å; Y361-Y363 PolarHBondContact O-N 3.38Å; Y361-T364 PolarHBondContact O-N 3.21Å; Y361-K365 HydrophobicContact CD2-CB 4.3Å; Y361-K365 HydrophobicContact CE1-CB 4.29Å; Y361-K365 HydrophobicContact CE1-CG 4.48Å; Y361-K365 HydrophobicContact CE2-CB 3.94Å; Y361-K365 HydrophobicContact CE2-CG 4.06Å; Y361-K365 VanDerWaalsContact O-CB 3.23Å; Y361-K365 WeakPolarHBondContact O-CB 3.47Å; Y361-K365 PolarHBondContact O-N 3.5Å
362I96.7Very high96Very high0 Ų013.1 Ų13.10%07%0.065CC..Hα-helixtrans-57.5-53.1-172.2-63.8164.6000109.8T263 T267 F328 S358 F359 T364 K365 D366T263-I362 HydrophobicContact CG2-CG2 3.73Å; T267-I362 HydrophobicContact CG2-CB 4.3Å; T267-I362 HydrophobicContact CG2-CD1 4.18Å; T267-I362 HydrophobicContact CG2-CG2 3.87Å; F328-I362 HydrophobicContact CD1-CD1 3.73Å; F328-I362 HydrophobicContact CE1-CD1 3.57Å; F328-I362 HydrophobicContact CE1-CG1 4.07Å; S358-I362 WeakPolarHBondContact O-CG1 3.08Å; S358-I362 PolarHBondContact O-N 2.93Å; S358-I362 VanDerWaalsContact O-N 3.13Å; S358-I362 WeakPolarHBondContact OG-CD1 3.3Å; F359-I362 PolarHBondContact O-N 3.21Å; I362-T364 PolarHBondContact O-N 2.88Å; I362-K365 PolarHBondContact O-N 2.92Å; I362-D366 VanDerWaalsContact CG2-OD2 3.3Å; I362-D366 WeakPolarHBondContact CG2-OD2 3.21Å; I362-D366 WeakPolarHBondContact O-CB 3.38Å; I362-D366 PolarHBondContact O-N 3.38Å
363Y93.7Very high96Very high11 Ų1116 Ų164%0.0438%0.078CC..Hα-helixtrans-63.2-42-176.8-85.6-66.2000113.9T267 A268 L271 W304 F359 Y361 S367 K390T267-Y363 HydrophobicContact CG2-CE2 4.01Å; A268-Y363 WeakPolarHBondContact CA-OH 3.4Å; L271-Y363 HydrophobicContact CD2-CE2 3.78Å; L271-Y363 VanDerWaalsContact CD2-OH 3.31Å; L271-Y363 WeakPolarHBondContact CD2-OH 3.23Å; W304-Y363 AromaticContact CH2-CD2 3.14Å; W304-Y363 HydrophobicContact CH2-CD2 3.14Å; W304-Y363 AromaticContact CH2-CE2 3.55Å; W304-Y363 HydrophobicContact CH2-CE2 3.55Å; W304-Y363 AromaticContact CH2-CG 3.84Å; W304-Y363 HydrophobicContact CH2-CG 3.84Å; W304-Y363 AromaticContact CZ2-CD2 3.38Å; W304-Y363 HydrophobicContact CZ2-CD2 3.38Å; W304-Y363 HydrophobicContact CZ2-CE2 4.24Å; W304-Y363 AromaticContact CZ2-CG 3.68Å; W304-Y363 HydrophobicContact CZ2-CG 3.68Å; W304-Y363 HydrophobicContact CZ3-CD2 4.05Å; W304-Y363 HydrophobicContact CZ3-CE2 4.25Å; F359-Y363 HydrophobicContact CB-CD2 4.08Å; F359-Y363 HydrophobicContact CB-CE2 4.33Å; F359-Y363 HydrophobicContact CD1-CD2 4.32Å; F359-Y363 AromaticContact CD1-CE2 3.85Å; F359-Y363 HydrophobicContact CD1-CE2 3.85Å; F359-Y363 HydrophobicContact CG-CE2 4.42Å; F359-Y363 WeakPolarHBondContact O-CB 3.43Å; F359-Y363 WeakPolarHBondContact O-CD2 3.5Å; F359-Y363 PolarHBondContact O-N 2.67Å; Y361-Y363 PolarHBondContact O-N 3.38Å; Y363-S367 VanDerWaalsContact O-CB 3.31Å; Y363-S367 WeakPolarHBondContact O-CB 3.35Å; Y363-S367 PolarHBondContact O-N 2.96Å; Y363-K390 HydrophobicContact CD1-CD 4.31Å; Y363-K390 HydrophobicContact CE1-CD 3.81Å; Y363-K390 HydrophobicContact CE1-CG 4.13Å
364T95.9Very high95.9Very high2 Ų213.7 Ų13.71%0.0127%0.067CC..Hα-helixtrans-71.4-43.2-179.8-66.10000110.5Y129 M132 N308 L311 G360 Y361 I362 V368Y129-T364 HydrophobicContact CD1-CG2 4Å; Y129-T364 HydrophobicContact CG-CG2 4.44Å; M132-T364 HydrophobicContact CB-CG2 4.09Å; M132-T364 HydrophobicContact SD-CG2 4.39Å; N308-T364 WeakPolarHBondContact OD1-CB 3.47Å; N308-T364 VanDerWaalsContact OD1-CG2 3.25Å; N308-T364 WeakPolarHBondContact OD1-CG2 3.32Å; N308-T364 PolarHBondContact OD1-OG1 3.01Å; L311-T364 HydrophobicContact CD2-CG2 3.83Å; G360-T364 PolarHBondContact O-OG1 3.12Å; Y361-T364 PolarHBondContact O-N 3.21Å; I362-T364 PolarHBondContact O-N 2.88Å; T364-V368 HydrophobicContact CG2-CG2 4.39Å; T364-V368 WeakPolarHBondContact O-CB 3.44Å; T364-V368 WeakPolarHBondContact O-CG2 3.36Å; T364-V368 PolarHBondContact O-N 2.93Å
365K95.7Very high95.6Very high20 Ų2013.5 Ų13.59%0.0877%0.069CC..Hα-helixtrans-74.9-39.3-174.7-169.758175.6-171.10112.5E315 Y324 Y361 I362 S367 V368 I369E315-K365 VanDerWaalsContact OE1-CD 3.29Å; E315-K365 WeakPolarHBondContact OE1-CD 3.25Å; E315-K365 WeakPolarHBondContact OE1-CE 3.41Å; E315-K365 IonicContact OE1-NZ 3.7Å; E315-K365 PolarHBondContact OE1-NZ 3.43Å; E315-K365 IonicContact OE2-NZ 2.72Å; Y324-K365 HydrophobicContact CE2-CG 4.07Å; Y361-K365 HydrophobicContact CD2-CB 4.3Å; Y361-K365 HydrophobicContact CE1-CB 4.29Å; Y361-K365 HydrophobicContact CE1-CG 4.48Å; Y361-K365 HydrophobicContact CE2-CB 3.94Å; Y361-K365 HydrophobicContact CE2-CG 4.06Å; Y361-K365 VanDerWaalsContact O-CB 3.23Å; Y361-K365 WeakPolarHBondContact O-CB 3.47Å; Y361-K365 PolarHBondContact O-N 3.5Å; I362-K365 PolarHBondContact O-N 2.92Å; K365-S367 PolarHBondContact O-N 2.91Å; K365-V368 PolarHBondContact O-N 2.85Å; K365-I369 HydrophobicContact CD-CD1 4.34Å; K365-I369 HydrophobicContact CD-CG1 4.24Å; K365-I369 HydrophobicContact CG-CD1 3.85Å; K365-I369 HydrophobicContact CG-CG1 4.25Å; K365-I369 WeakPolarHBondContact O-CB 3.31Å; K365-I369 VanDerWaalsContact O-CG1 3.27Å; K365-I369 WeakPolarHBondContact O-CG1 3.45Å; K365-I369 PolarHBondContact O-N 3.31Å
366D96.5Very high95.3Very high0 Ų019.4 Ų19.40%011%0.107CC..Hα-helixtrans-56-53.2174.3-793000110.2V260 D264 Y324 I362 V368 I369 V370 Y386V260-D366 HydrophobicContact CG1-CB 3.57Å; V260-D366 WeakPolarHBondContact CG1-O 3.46Å; D264-D366 PolarHBondContact N-OD2 3.43Å; Y324-D366 VanDerWaalsContact CE1-OD1 3.26Å; Y324-D366 WeakPolarHBondContact CE1-OD1 3.42Å; Y324-D366 VanDerWaalsContact CZ-OD1 3.28Å; Y324-D366 PolarHBondContact OH-OD1 2.83Å; I362-D366 VanDerWaalsContact CG2-OD2 3.3Å; I362-D366 WeakPolarHBondContact CG2-OD2 3.21Å; I362-D366 WeakPolarHBondContact O-CB 3.38Å; I362-D366 PolarHBondContact O-N 3.38Å; D366-V368 PolarHBondContact O-N 3.32Å; D366-I369 PolarHBondContact O-N 3.48Å; D366-V370 WeakPolarHBondContact O-CG2 3.35Å; D366-V370 PolarHBondContact O-N 3.28Å; D366-V370 VanDerWaalsContact O-N 3.09Å; D366-Y386 HydrophobicContact CB-CE2 3.87Å; D366-Y386 WeakPolarHBondContact CB-OH 3.31Å
367S95.7Very high94.8Very high0 Ų024.9 Ų24.90%014%0.136CC..Hα-helixtrans-60.4-43.7177.7-178.70000112.2Q116 M132 Y363 K365 I369 V370 Q371 M383Q116-S367 PolarHBondContact OE1-OG 3.24Å; M132-S367 WeakPolarHBondContact CE-OG 3.46Å; Y363-S367 VanDerWaalsContact O-CB 3.31Å; Y363-S367 WeakPolarHBondContact O-CB 3.35Å; Y363-S367 PolarHBondContact O-N 2.96Å; K365-S367 PolarHBondContact O-N 2.91Å; S367-I369 PolarHBondContact O-N 2.95Å; S367-V370 PolarHBondContact O-N 3.42Å; S367-Q371 WeakPolarHBondContact O-CG 3.49Å; S367-Q371 PolarHBondContact O-N 2.96Å; S367-M383 VanDerWaalsContact OG-CE 3.31Å; S367-M383 WeakPolarHBondContact OG-CE 3.19Å
368V96.5Very high94.5Very high2 Ų223.8 Ų23.81%0.01213%0.13CC..Hα-helixtrans-64.1-39.4175.8167.90000112.6I125 Y129 M132 T364 K365 D366 V370 Q371 E372I125-V368 HydrophobicContact CD1-CG1 3.87Å; Y129-V368 HydrophobicContact CD1-CG2 4.03Å; Y129-V368 HydrophobicContact CE1-CB 4.38Å; Y129-V368 HydrophobicContact CE1-CG1 4.04Å; Y129-V368 HydrophobicContact CE1-CG2 3.78Å; M132-V368 HydrophobicContact CE-CG2 4.16Å; M132-V368 HydrophobicContact SD-CG2 3.79Å; T364-V368 HydrophobicContact CG2-CG2 4.39Å; T364-V368 WeakPolarHBondContact O-CB 3.44Å; T364-V368 WeakPolarHBondContact O-CG2 3.36Å; T364-V368 PolarHBondContact O-N 2.93Å; K365-V368 PolarHBondContact O-N 2.85Å; D366-V368 PolarHBondContact O-N 3.32Å; V368-V370 VanDerWaalsContact C-N 3.35Å; V368-Q371 WeakPolarHBondContact O-CB 3.14Å; V368-Q371 PolarHBondContact O-N 3.28Å; V368-E372 HydrophobicContact CG1-CG 4Å; V368-E372 WeakPolarHBondContact O-CB 3.26Å; V368-E372 WeakPolarHBondContact O-CG 3.37Å; V368-E372 PolarHBondContact O-N 2.84Å
369I95.9Very high94.3Very high2 Ų224.4 Ų24.41%0.0113%0.132CC..Hα-helixtrans-62.2-45.7178.1-74.2167.1000109.8V260 Y324 K365 D366 S367 Q371 E372 E373V260-I369 HydrophobicContact CG2-CB 4.06Å; V260-I369 HydrophobicContact CG2-CD1 3.83Å; V260-I369 HydrophobicContact CG2-CG2 3.79Å; Y324-I369 HydrophobicContact CE2-CD1 4.21Å; Y324-I369 WeakPolarHBondContact OH-CD1 3.1Å; K365-I369 HydrophobicContact CD-CD1 4.34Å; K365-I369 HydrophobicContact CD-CG1 4.24Å; K365-I369 HydrophobicContact CG-CD1 3.85Å; K365-I369 HydrophobicContact CG-CG1 4.25Å; K365-I369 WeakPolarHBondContact O-CB 3.31Å; K365-I369 VanDerWaalsContact O-CG1 3.27Å; K365-I369 WeakPolarHBondContact O-CG1 3.45Å; K365-I369 PolarHBondContact O-N 3.31Å; D366-I369 PolarHBondContact O-N 3.48Å; S367-I369 PolarHBondContact O-N 2.95Å; I369-Q371 VanDerWaalsContact C-N 3.28Å; I369-Q371 PolarHBondContact O-N 2.9Å; I369-E372 PolarHBondContact O-N 2.76Å; I369-E373 HydrophobicContact CG2-CB 4.5Å; I369-E373 HydrophobicContact CG2-CG 4.24Å; I369-E373 VanDerWaalsContact O-CB 3.32Å; I369-E373 WeakPolarHBondContact O-CB 3.46Å; I369-E373 PolarHBondContact O-N 3.02Å
370V96.9Very high94.2Very high0 Ų026 Ų260%014%0.139CC..Hα-helixtrans-62-38.9175.7-177.20000110.8V260 F261 D366 S367 V368 T374 M382 M383 Y386V260-V370 HydrophobicContact CG1-CG2 3.74Å; F261-V370 HydrophobicContact CD2-CG2 4.39Å; F261-V370 HydrophobicContact CE2-CG1 4.34Å; F261-V370 HydrophobicContact CE2-CG2 3.95Å; D366-V370 WeakPolarHBondContact O-CG2 3.35Å; D366-V370 PolarHBondContact O-N 3.28Å; D366-V370 VanDerWaalsContact O-N 3.09Å; S367-V370 PolarHBondContact O-N 3.42Å; V368-V370 VanDerWaalsContact C-N 3.35Å; V370-T374 WeakPolarHBondContact O-CB 3.45Å; V370-T374 PolarHBondContact O-N 2.94Å; V370-T374 PolarHBondContact O-OG1 3.01Å; V370-M382 HydrophobicContact CG1-CB 3.79Å; V370-M383 HydrophobicContact CB-SD 3.65Å; V370-M383 HydrophobicContact CG1-SD 3.47Å; V370-M383 WeakPolarHBondContact CG1-SD 3.32Å; V370-Y386 HydrophobicContact CG2-CD2 3.99Å; V370-Y386 HydrophobicContact CG2-CG 4.43Å
371Q95Very high94Very high2 Ų226.6 Ų26.61%0.00914%0.142CC..Hα-helixtrans-67.7-31.5177.7-70.8168.84.900115Q116 K120 R128 S367 V368 I369 M383Q116-Q371 PolarHBondContact O-NE2 3.44Å; K120-Q371 HydrophobicContact CB-CB 4.32Å; K120-Q371 HydrophobicContact CB-CG 3.92Å; K120-Q371 HydrophobicContact CD-CB 4.11Å; K120-Q371 HydrophobicContact CG-CB 4.25Å; K120-Q371 HydrophobicContact CG-CG 4.34Å; K120-Q371 PolarHBondContact NZ-O 3.32Å; R128-Q371 VanDerWaalsContact CD-OE1 3.22Å; S367-Q371 WeakPolarHBondContact O-CG 3.49Å; S367-Q371 PolarHBondContact O-N 2.96Å; V368-Q371 WeakPolarHBondContact O-CB 3.14Å; V368-Q371 PolarHBondContact O-N 3.28Å; I369-Q371 VanDerWaalsContact C-N 3.28Å; I369-Q371 PolarHBondContact O-N 2.9Å; Q371-M383 HydrophobicContact CB-SD 4.33Å; Q371-M383 HydrophobicContact CG-CE 3.89Å; Q371-M383 HydrophobicContact CG-CG 4.07Å; Q371-M383 HydrophobicContact CG-SD 3.47Å; Q371-M383 WeakPolarHBondContact CG-SD 3.42Å
372E95Very high94Very high90 Ų9026.6 Ų26.642%0.42114%0.142SC..Hα-helixtrans-101.2-29.3-174.2-64.9-57.314200113.4K120 I125 R128 V368 I369K120-E372 IonicContact NZ-OE1 2.77Å; K120-E372 PolarHBondContact NZ-OE1 2.9Å; K120-E372 IonicContact NZ-OE2 2.7Å; K120-E372 PolarHBondContact NZ-OE2 3.17Å; I125-E372 HydrophobicContact CD1-CG 4.44Å; R128-E372 IonicContact CZ-OE1 3.58Å; R128-E372 IonicContact NH1-OE1 3.54Å; R128-E372 PolarHBondContact NH1-OE1 3.36Å; R128-E372 IonicContact NH2-OE1 2.67Å; V368-E372 HydrophobicContact CG1-CG 4Å; V368-E372 WeakPolarHBondContact O-CB 3.26Å; V368-E372 WeakPolarHBondContact O-CG 3.37Å; V368-E372 PolarHBondContact O-N 2.84Å; I369-E372 PolarHBondContact O-N 2.76Å
373E95.4Very high93.9Very high61 Ų6126.6 Ų26.629%0.28514%0.142SC..Hα-helixtrans-97.7-5-177.1-62.6-176.3-166.800113.5S256 I257 R320 I369S256-E373 WeakPolarHBondContact CB-OE2 3.35Å; S256-E373 PolarHBondContact OG-OE2 3.33Å; I257-E373 HydrophobicContact CD1-CB 4.19Å; I257-E373 HydrophobicContact CG1-CB 4.38Å; R320-E373 IonicContact CZ-OE1 3.93Å; R320-E373 VanDerWaalsContact CZ-OE1 3.23Å; R320-E373 IonicContact NH1-OE1 2.67Å; R320-E373 PolarHBondContact NH1-OE1 3.43Å; R320-E373 IonicContact NH1-OE2 2.68Å; R320-E373 IonicContact NH2-OE1 2.98Å; R320-E373 PolarHBondContact NH2-OE1 3.44Å; I369-E373 HydrophobicContact CG2-CB 4.5Å; I369-E373 HydrophobicContact CG2-CG 4.24Å; I369-E373 VanDerWaalsContact O-CB 3.32Å; I369-E373 WeakPolarHBondContact O-CB 3.46Å; I369-E373 PolarHBondContact O-N 3.02Å
374T94.6Very high93.8Very high9 Ų926 Ų266%0.05514%0.14CC..SBendtrans-88.8145.4169.6-55.60000110.3E252 V370 Q378 M379 M382E252-T374 HydrophobicContact CB-CG2 4.35Å; E252-T374 HydrophobicContact CG-CG2 3.99Å; E252-T374 WeakPolarHBondContact OE2-CA 3.34Å; E252-T374 WeakPolarHBondContact OE2-CG2 3.49Å; V370-T374 WeakPolarHBondContact O-CB 3.45Å; V370-T374 PolarHBondContact O-N 2.94Å; V370-T374 PolarHBondContact O-OG1 3.01Å; T374-Q378 HydrophobicContact CG2-CB 3.87Å; T374-M379 HydrophobicContact CG2-CB 4.48Å; T374-M382 HydrophobicContact CG2-CB 3.82Å; T374-M382 HydrophobicContact CG2-CG 3.39Å
375S92.2Very high93.7Very high38 Ų3826.2 Ų26.227%0.26614%0.14SC..  trans-55.4144.2172.172.10000112.7E252 L377 Q378 M379E252-S375 VanDerWaalsContact OE1-CB 3.3Å; E252-S375 WeakPolarHBondContact OE1-CB 3.34Å; E252-S375 PolarHBondContact OE1-OG 2.67Å; E252-S375 PolarHBondContact OE2-N 3.43Å; S375-L377 PolarHBondContact O-N 3.18Å; S375-L377 VanDerWaalsContact O-N 3.08Å; S375-Q378 PolarHBondContact O-N 3.42Å; S375-Q378 WeakPolarHBondContact OG-CG 3.31Å; S375-Q378 PolarHBondContact OG-N 2.98Å; S375-M379 PolarHBondContact O-N 2.67Å
376P88.3Confident93.6Very high124 Ų12425.2 Ų25.281%0.80514%0.136SC*.THydrogen-bonded Turntrans-54.7-32.9-179.7-28.435.1000114
377L86.9Confident93.4Very high116 Ų11625.4 Ų25.461%0.60714%0.138SC*.THydrogen-bonded Turntrans-67.7-36.8178.4-175.665000112.5S375S375-L377 PolarHBondContact O-N 3.18Å; S375-L377 VanDerWaalsContact O-N 3.08Å
378Q90.7Very high93.1Very high22 Ų2225.7 Ų25.710%0.10314%0.139CC..THydrogen-bonded Turntrans-101.3-9.3-174.7-59.6-60.4-11.400113.9P249 E252 T374 S375 K380 K381 M382P249-Q378 HydrophobicContact CB-CB 4.11Å; P249-Q378 HydrophobicContact CB-CG 3.97Å; P249-Q378 HydrophobicContact CG-CB 4.05Å; P249-Q378 HydrophobicContact CG-CG 4.1Å; E252-Q378 HydrophobicContact CG-CB 3.92Å; E252-Q378 HydrophobicContact CG-CG 4.19Å; T374-Q378 HydrophobicContact CG2-CB 3.87Å; S375-Q378 PolarHBondContact O-N 3.42Å; S375-Q378 WeakPolarHBondContact OG-CG 3.31Å; S375-Q378 PolarHBondContact OG-N 2.98Å; Q378-K380 VanDerWaalsContact C-N 3.29Å; Q378-K380 PolarHBondContact O-N 2.86Å; Q378-K380 VanDerWaalsContact O-N 3.17Å; Q378-K381 WeakPolarHBondContact O-CA 3.23Å; Q378-K381 WeakPolarHBondContact O-CB 3.45Å; Q378-K381 PolarHBondContact O-N 3.19Å; Q378-M382 PolarHBondContact O-N 3.3Å
379M93Very high92.9Very high12 Ų1226.6 Ų26.66%0.05915%0.145CC..Hα-helixtrans-48.6-47.7-176.4-179.3-81.4-6900112.6K120 L121 T374 S375 K381 M382 M383K120-M379 HydrophobicContact CG-CE 3.82Å; K120-M379 HydrophobicContact CG-SD 4.15Å; L121-M379 HydrophobicContact CD2-CE 3.88Å; T374-M379 HydrophobicContact CG2-CB 4.48Å; S375-M379 PolarHBondContact O-N 2.67Å; M379-K381 VanDerWaalsContact C-N 3.33Å; M379-K381 PolarHBondContact O-N 3.35Å; M379-M382 PolarHBondContact O-N 3Å; M379-M383 HydrophobicContact CG-CG 4.33Å; M379-M383 WeakPolarHBondContact O-CB 3.31Å; M379-M383 VanDerWaalsContact O-CG 3.28Å; M379-M383 WeakPolarHBondContact O-CG 3.42Å; M379-M383 PolarHBondContact O-N 3.3Å; M379-M383 HydrophobicContact SD-CG 3.73Å
380K92.3Very high92.6Very high33 Ų3327.3 Ų27.314%0.14315%0.148CC..Hα-helixtrans-64.2-36-178.7-55.3-176.1-166.1165.90112.6G62 L65 I117 Q378 S384G62-K380 WeakPolarHBondContact CA-O 3.27Å; L65-K380 HydrophobicContact CB-CB 4.32Å; L65-K380 HydrophobicContact CB-CD 3.7Å; L65-K380 HydrophobicContact CD1-CD 4.49Å; L65-K380 PolarHBondContact O-NZ 3.39Å; L65-K380 VanDerWaalsContact O-NZ 3.15Å; I117-K380 HydrophobicContact CG2-CG 4.41Å; Q378-K380 VanDerWaalsContact C-N 3.29Å; Q378-K380 PolarHBondContact O-N 2.86Å; Q378-K380 VanDerWaalsContact O-N 3.17Å; K380-S384 WeakPolarHBondContact O-CB 3.28Å; K380-S384 PolarHBondContact O-N 3.02Å; K380-S384 PolarHBondContact O-OG 3.3Å
381K92.4Very high92.1Very high14 Ų1427.8 Ų27.86%0.06115%0.151CC..Hα-helixtrans-68.2-50.6174.6-59.4-159.4-165.4-163.70110.8E63 P246 P249 Q378 M379 M383 S384 F385E63-K381 WeakPolarHBondContact OE2-CE 3.28Å; E63-K381 IonicContact OE2-NZ 3.23Å; E63-K381 PolarHBondContact OE2-NZ 3.31Å; P246-K381 PolarHBondContact O-NZ 2.82Å; P249-K381 HydrophobicContact CG-CB 3.95Å; P249-K381 HydrophobicContact CG-CD 4.02Å; Q378-K381 WeakPolarHBondContact O-CA 3.23Å; Q378-K381 WeakPolarHBondContact O-CB 3.45Å; Q378-K381 PolarHBondContact O-N 3.19Å; M379-K381 VanDerWaalsContact C-N 3.33Å; M379-K381 PolarHBondContact O-N 3.35Å; K381-M383 VanDerWaalsContact C-N 3.31Å; K381-M383 PolarHBondContact O-N 3.3Å; K381-S384 WeakPolarHBondContact O-CA 3.16Å; K381-S384 WeakPolarHBondContact O-CB 3.31Å; K381-S384 PolarHBondContact O-N 3.3Å; K381-F385 HydrophobicContact CB-CE2 4.13Å; K381-F385 WeakPolarHBondContact O-CD2 3.47Å; K381-F385 PolarHBondContact O-N 2.67Å
382M94.9Very high91.8Very high0 Ų028.4 Ų28.40%015%0.154CC..Hα-helixtrans-60.4-39.6179.2-68.8-58.5-70.400112.6P249 E252 F253 I257 F261 V370 T374 Q378 M379 S384 F385 Y386P249-M382 HydrophobicContact CB-SD 4.21Å; P249-M382 HydrophobicContact CG-SD 4.34Å; E252-M382 HydrophobicContact CB-CE 3.99Å; E252-M382 HydrophobicContact CB-CG 4.1Å; E252-M382 HydrophobicContact CB-SD 3.96Å; E252-M382 HydrophobicContact CG-CG 4.24Å; E252-M382 HydrophobicContact CG-SD 4.45Å; F253-M382 HydrophobicContact CD2-CE 3.97Å; F253-M382 HydrophobicContact CD2-SD 4.5Å; F253-M382 HydrophobicContact CE1-CE 4.2Å; F253-M382 HydrophobicContact CE2-CE 3.61Å; F253-M382 HydrophobicContact CE2-SD 3.93Å; F253-M382 HydrophobicContact CG-CE 4.44Å; F253-M382 HydrophobicContact CZ-CE 3.74Å; F253-M382 HydrophobicContact CZ-SD 4.4Å; I257-M382 HydrophobicContact CG2-CE 3.77Å; F261-M382 HydrophobicContact CE2-CE 3.9Å; F261-M382 HydrophobicContact CZ-CE 4.15Å; V370-M382 HydrophobicContact CG1-CB 3.79Å; T374-M382 HydrophobicContact CG2-CB 3.82Å; T374-M382 HydrophobicContact CG2-CG 3.39Å; Q378-M382 PolarHBondContact O-N 3.3Å; M379-M382 PolarHBondContact O-N 3Å; M382-S384 VanDerWaalsContact C-N 3.31Å; M382-S384 PolarHBondContact O-N 2.96Å; M382-F385 PolarHBondContact O-N 3.18Å; M382-Y386 WeakPolarHBondContact O-CB 3.37Å; M382-Y386 PolarHBondContact O-N 2.98Å
383M94.2Very high91.6Very high0 Ų024.1 Ų24.10%013%0.134CC..Hα-helixtrans-66.8-31.1174.5-70.5-44.9-59.500113.4Q116 I117 S367 V370 Q371 M379 K381 Y386 G387Q116-M383 HydrophobicContact CB-CE 3.59Å; I117-M383 HydrophobicContact CD1-CB 4.24Å; I117-M383 HydrophobicContact CG1-CB 3.51Å; I117-M383 HydrophobicContact CG1-CG 4.27Å; S367-M383 VanDerWaalsContact OG-CE 3.31Å; S367-M383 WeakPolarHBondContact OG-CE 3.19Å; V370-M383 HydrophobicContact CB-SD 3.65Å; V370-M383 HydrophobicContact CG1-SD 3.47Å; V370-M383 WeakPolarHBondContact CG1-SD 3.32Å; Q371-M383 HydrophobicContact CB-SD 4.33Å; Q371-M383 HydrophobicContact CG-CE 3.89Å; Q371-M383 HydrophobicContact CG-CG 4.07Å; Q371-M383 HydrophobicContact CG-SD 3.47Å; Q371-M383 WeakPolarHBondContact CG-SD 3.42Å; M379-M383 HydrophobicContact CG-CG 4.33Å; M379-M383 WeakPolarHBondContact O-CB 3.31Å; M379-M383 VanDerWaalsContact O-CG 3.28Å; M379-M383 WeakPolarHBondContact O-CG 3.42Å; M379-M383 PolarHBondContact O-N 3.3Å; M379-M383 HydrophobicContact SD-CG 3.73Å; K381-M383 VanDerWaalsContact C-N 3.31Å; K381-M383 PolarHBondContact O-N 3.3Å; M383-Y386 HydrophobicContact CE-CD1 3.76Å; M383-Y386 HydrophobicContact CE-CE1 4.44Å; M383-Y386 HydrophobicContact CE-CG 4.31Å; M383-Y386 PolarHBondContact O-N 3.42Å; M383-G387 PolarHBondContact O-N 2.91Å
384S93Very high91.3Very high0 Ų021.9 Ų21.90%013%0.125CC..Hα-helixtrans-70.8-39174.7-61.10000111.5N58 G62 K380 K381 M382 G387 L388N58-S384 WeakPolarHBondContact O-CB 3.33Å; G62-S384 WeakPolarHBondContact CA-OG 3.45Å; G62-S384 PolarHBondContact N-OG 2.85Å; K380-S384 WeakPolarHBondContact O-CB 3.28Å; K380-S384 PolarHBondContact O-N 3.02Å; K380-S384 PolarHBondContact O-OG 3.3Å; K381-S384 WeakPolarHBondContact O-CA 3.16Å; K381-S384 WeakPolarHBondContact O-CB 3.31Å; K381-S384 PolarHBondContact O-N 3.3Å; M382-S384 VanDerWaalsContact C-N 3.31Å; M382-S384 PolarHBondContact O-N 2.96Å; S384-G387 PolarHBondContact O-N 3.35Å; S384-L388 PolarHBondContact O-N 2.84Å
385F92.9Very high90.7Very high5 Ų521.7 Ų21.72%0.02213%0.125CC..Hα-helixtrans-68.3-36.5170.8-64.9-61.4000112.4P59 F202 F247 L248 F261 K381 M382 L388 T389P59-F385 HydrophobicContact CB-CD1 4.18Å; P59-F385 HydrophobicContact CB-CE1 3.79Å; F202-F385 HydrophobicContact CD2-CE1 4.11Å; F202-F385 HydrophobicContact CE1-CE1 4.13Å; F202-F385 AromaticContact CE2-CD1 3.86Å; F202-F385 HydrophobicContact CE2-CD1 3.86Å; F202-F385 AromaticContact CE2-CE1 3.48Å; F202-F385 HydrophobicContact CE2-CE1 3.48Å; F202-F385 VanDerWaalsContact CE2-CE1 3.48Å; F202-F385 HydrophobicContact CE2-CZ 4.49Å; F202-F385 AromaticContact CZ-CD1 3.68Å; F202-F385 HydrophobicContact CZ-CD1 3.68Å; F202-F385 AromaticContact CZ-CE1 3.49Å; F202-F385 HydrophobicContact CZ-CE1 3.49Å; F202-F385 VanDerWaalsContact CZ-CE1 3.49Å; F247-F385 HydrophobicContact CD1-CE1 4.36Å; F247-F385 AromaticContact CD1-CZ 3.95Å; F247-F385 HydrophobicContact CD1-CZ 3.95Å; F247-F385 AromaticContact CE1-CE1 3.86Å; F247-F385 HydrophobicContact CE1-CE1 3.86Å; F247-F385 AromaticContact CE1-CZ 3.78Å; F247-F385 HydrophobicContact CE1-CZ 3.78Å; F247-F385 HydrophobicContact CZ-CE1 4.48Å; F247-F385 HydrophobicContact CZ-CZ 4.33Å; F247-F385 WeakPolarHBondContact O-CE2 3.37Å; F247-F385 VanDerWaalsContact O-CZ 3.3Å; F247-F385 WeakPolarHBondContact O-CZ 3.33Å; L248-F385 HydrophobicContact CB-CE2 4.3Å; L248-F385 HydrophobicContact CB-CZ 3.97Å; L248-F385 HydrophobicContact CD1-CD1 3.83Å; L248-F385 HydrophobicContact CD1-CD2 3.49Å; L248-F385 VanDerWaalsContact CD1-CD2 3.49Å; L248-F385 HydrophobicContact CD1-CE1 3.77Å; L248-F385 HydrophobicContact CD1-CE2 3.47Å; L248-F385 VanDerWaalsContact CD1-CE2 3.47Å; L248-F385 HydrophobicContact CD1-CG 3.7Å; L248-F385 HydrophobicContact CD1-CZ 3.61Å; L248-F385 HydrophobicContact CG-CE2 4.48Å; L248-F385 HydrophobicContact CG-CZ 4.41Å; F261-F385 HydrophobicContact CE1-CB 4.02Å; F261-F385 HydrophobicContact CZ-CB 4.11Å; K381-F385 HydrophobicContact CB-CE2 4.13Å; K381-F385 WeakPolarHBondContact O-CD2 3.47Å; K381-F385 PolarHBondContact O-N 2.67Å; M382-F385 PolarHBondContact O-N 3.18Å; F385-L388 HydrophobicContact CD1-CD2 4.48Å; F385-L388 VanDerWaalsContact O-CB 3.31Å; F385-L388 WeakPolarHBondContact O-CB 3.48Å; F385-L388 PolarHBondContact O-N 3.25Å; F385-T389 PolarHBondContact O-N 3.45Å; F385-T389 PolarHBondContact O-OG1 3.42Å
386Y94.1Very high90.5Very high0 Ų021.1 Ų21.10%012%0.119CC..Hα-helixtrans-60.5-46.1172.8176-99.1000110.9Q116 V260 D264 D366 V370 M382 M383 L388 T389 K390Q116-Y386 HydrophobicContact CG-CD1 4.27Å; Q116-Y386 HydrophobicContact CG-CE1 4.42Å; V260-Y386 HydrophobicContact CG1-CE2 4.32Å; D264-Y386 HydrophobicContact CB-CD2 4.42Å; D264-Y386 HydrophobicContact CB-CE2 3.64Å; D264-Y386 WeakPolarHBondContact OD1-CE2 3.47Å; D264-Y386 PolarHBondContact OD1-OH 2.82Å; D366-Y386 HydrophobicContact CB-CE2 3.87Å; D366-Y386 WeakPolarHBondContact CB-OH 3.31Å; V370-Y386 HydrophobicContact CG2-CD2 3.99Å; V370-Y386 HydrophobicContact CG2-CG 4.43Å; M382-Y386 WeakPolarHBondContact O-CB 3.37Å; M382-Y386 PolarHBondContact O-N 2.98Å; M383-Y386 HydrophobicContact CE-CD1 3.76Å; M383-Y386 HydrophobicContact CE-CE1 4.44Å; M383-Y386 HydrophobicContact CE-CG 4.31Å; M383-Y386 PolarHBondContact O-N 3.42Å; Y386-L388 VanDerWaalsContact C-N 3.29Å; Y386-L388 PolarHBondContact O-N 3.44Å; Y386-T389 PolarHBondContact O-N 2.9Å; Y386-K390 PolarHBondContact O-N 3.45Å
387G90.8Very high90.5Very high3 Ų315.2 Ų15.23%0.0318%0.08CC..Hα-helixtrans-58.6-38.7172.500000113.3M383 S384 N391M383-G387 PolarHBondContact O-N 2.91Å; S384-G387 PolarHBondContact O-N 3.35Å; G387-N391 PolarHBondContact O-N 3.42Å; G387-N391 VanDerWaalsContact O-N 3.15Å; G387-N391 PolarHBondContact O-ND2 3.16Å
388L91.1Very high90.4Very high6 Ų611.1 Ų11.13%0.0316%0.061CC..Hα-helixtrans-61.8-48.7172.7174.974.7000112V55 N58 P59 F202 I206 S384 F385 Y386 K390 N391 L392V55-L388 HydrophobicContact CB-CD1 4.36Å; V55-L388 HydrophobicContact CG1-CD1 3.7Å; V55-L388 VanDerWaalsContact O-CD1 3.23Å; V55-L388 WeakPolarHBondContact O-CD1 3.46Å; N58-L388 HydrophobicContact CB-CB 4.05Å; N58-L388 HydrophobicContact CB-CD1 4.43Å; P59-L388 HydrophobicContact CG-CB 4.45Å; P59-L388 HydrophobicContact CG-CD1 4.05Å; P59-L388 HydrophobicContact CG-CD2 3.91Å; P59-L388 HydrophobicContact CG-CG 4.37Å; F202-L388 HydrophobicContact CE1-CD2 3.83Å; F202-L388 HydrophobicContact CZ-CD2 3.39Å; I206-L388 HydrophobicContact CD1-CD1 4.5Å; I206-L388 HydrophobicContact CD1-CD2 3.85Å; I206-L388 HydrophobicContact CG1-CD2 4.47Å; S384-L388 PolarHBondContact O-N 2.84Å; F385-L388 HydrophobicContact CD1-CD2 4.48Å; F385-L388 VanDerWaalsContact O-CB 3.31Å; F385-L388 WeakPolarHBondContact O-CB 3.48Å; F385-L388 PolarHBondContact O-N 3.25Å; Y386-L388 VanDerWaalsContact C-N 3.29Å; Y386-L388 PolarHBondContact O-N 3.44Å; L388-K390 VanDerWaalsContact C-N 3.29Å; L388-K390 PolarHBondContact O-N 2.91Å; L388-N391 PolarHBondContact O-N 3.33Å; L388-N391 VanDerWaalsContact O-N 3.08Å; L388-L392 HydrophobicContact CD1-CD1 4.26Å; L388-L392 HydrophobicContact CD1-CG 4.15Å; L388-L392 HydrophobicContact CD2-CD1 4.28Å; L388-L392 HydrophobicContact CG-CD1 3.91Å; L388-L392 HydrophobicContact CG-CG 4.18Å; L388-L392 WeakPolarHBondContact O-CG 3.02Å; L388-L392 PolarHBondContact O-N 2.99Å
389T91.3Very high89.9Confident21 Ų2113 Ų1313%0.1297%0.074CC..Hα-helixtrans-58.5-42.7-179.2-64.80000111.4F261 L265 F385 Y386 N391 L392 G393F261-T389 HydrophobicContact CD1-CG2 4.19Å; F261-T389 VanDerWaalsContact CD1-OG1 3.25Å; F261-T389 WeakPolarHBondContact CD1-OG1 3.19Å; F261-T389 WeakPolarHBondContact CE1-OG1 3.46Å; F261-T389 WeakPolarHBondContact O-CG2 3.32Å; L265-T389 HydrophobicContact CB-CG2 3.68Å; L265-T389 HydrophobicContact CD1-CG2 4Å; L265-T389 WeakPolarHBondContact CD1-O 3.44Å; L265-T389 HydrophobicContact CG-CG2 4.43Å; F385-T389 PolarHBondContact O-N 3.45Å; F385-T389 PolarHBondContact O-OG1 3.42Å; Y386-T389 PolarHBondContact O-N 2.9Å; T389-N391 VanDerWaalsContact C-N 3.34Å; T389-N391 PolarHBondContact O-N 2.81Å; T389-L392 PolarHBondContact O-N 3.44Å; T389-G393 PolarHBondContact O-N 3.35Å
390K88.7Confident89.6Confident17 Ų1716.2 Ų16.27%0.0749%0.091CC..Hα-helixtrans-58-45.7173.2-178.1172.6178170.60112.4D264 A268 Y363 Y386 L388 G393 A394D264-K390 VanDerWaalsContact OD2-CA 3.27Å; D264-K390 WeakPolarHBondContact OD2-CA 3.36Å; D264-K390 WeakPolarHBondContact OD2-CB 3.19Å; D264-K390 PolarHBondContact OD2-N 3.08Å; D264-K390 VanDerWaalsContact OD2-N 3.11Å; A268-K390 HydrophobicContact CB-CG 4.46Å; A268-K390 WeakPolarHBondContact CB-O 3.47Å; Y363-K390 HydrophobicContact CD1-CD 4.31Å; Y363-K390 HydrophobicContact CE1-CD 3.81Å; Y363-K390 HydrophobicContact CE1-CG 4.13Å; Y386-K390 PolarHBondContact O-N 3.45Å; L388-K390 VanDerWaalsContact C-N 3.29Å; L388-K390 PolarHBondContact O-N 2.91Å; K390-G393 PolarHBondContact O-N 2.78Å; K390-A394 WeakPolarHBondContact O-CB 3.36Å; K390-A394 PolarHBondContact O-N 2.9Å
391N87.7Confident89.5Confident11 Ų1114.6 Ų14.66%0.0598%0.084CC..Hα-helixtrans-71.7-36.6-178.8-74.3-40.3000113.1L54 V55 N58 M112 G387 L388 T389 A394 S395L54-N391 HydrophobicContact CD2-CB 3.69Å; V55-N391 HydrophobicContact CG2-CB 4.41Å; N58-N391 PolarHBondContact ND2-ND2 3.35Å; N58-N391 PolarHBondContact OD1-ND2 3.5Å; M112-N391 WeakPolarHBondContact CE-OD1 3.39Å; M112-N391 PolarHBondContact SD-OD1 3.07Å; G387-N391 PolarHBondContact O-N 3.42Å; G387-N391 VanDerWaalsContact O-N 3.15Å; G387-N391 PolarHBondContact O-ND2 3.16Å; L388-N391 PolarHBondContact O-N 3.33Å; L388-N391 VanDerWaalsContact O-N 3.08Å; T389-N391 VanDerWaalsContact C-N 3.34Å; T389-N391 PolarHBondContact O-N 2.81Å; N391-A394 PolarHBondContact O-N 3.12Å; N391-S395 WeakPolarHBondContact O-CB 3.2Å; N391-S395 PolarHBondContact O-N 3.36Å
392L88.4Confident89.2Confident14 Ų1414.8 Ų14.87%0.0739%0.09CC..Hα-helixtrans-62.9-45.6169.8-72.7176.4000110.6V55 I206 I209 M210 L265 L388 T389 A394 S395 I396V55-L392 HydrophobicContact CG1-CD2 3.83Å; V55-L392 HydrophobicContact CG2-CD2 4.24Å; I206-L392 HydrophobicContact CD1-CD1 3.97Å; I209-L392 HydrophobicContact CG2-CD2 4.38Å; M210-L392 HydrophobicContact CE-CD2 3.52Å; M210-L392 HydrophobicContact SD-CD2 4.36Å; L265-L392 HydrophobicContact CD1-CB 4.2Å; L388-L392 HydrophobicContact CD1-CD1 4.26Å; L388-L392 HydrophobicContact CD1-CG 4.15Å; L388-L392 HydrophobicContact CD2-CD1 4.28Å; L388-L392 HydrophobicContact CG-CD1 3.91Å; L388-L392 HydrophobicContact CG-CG 4.18Å; L388-L392 WeakPolarHBondContact O-CG 3.02Å; L388-L392 PolarHBondContact O-N 2.99Å; T389-L392 PolarHBondContact O-N 3.44Å; L392-A394 VanDerWaalsContact C-N 3.31Å; L392-A394 PolarHBondContact O-N 3.39Å; L392-S395 PolarHBondContact O-N 3.22Å; L392-I396 HydrophobicContact CB-CD1 4.49Å; L392-I396 WeakPolarHBondContact O-CB 3.3Å; L392-I396 WeakPolarHBondContact O-CD1 3.26Å; L392-I396 WeakPolarHBondContact O-CG1 3.48Å; L392-I396 PolarHBondContact O-N 3.01Å
393G91.5Very high88.7Confident0 Ų022.8 Ų22.80%012%0.121CC..Hα-helixtrans-61.2-39.717700000112.2I269 T389 K390 G397I269-G393 WeakPolarHBondContact CA-O 3.47Å; I269-G393 WeakPolarHBondContact CG1-O 3.49Å; I269-G393 PolarHBondContact N-O 3.46Å; T389-G393 PolarHBondContact O-N 3.35Å; K390-G393 PolarHBondContact O-N 2.78Å; G393-G397 WeakPolarHBondContact O-CA 3.3Å; G393-G397 PolarHBondContact O-N 2.88Å
394A87.7Confident88.6Confident14 Ų1424.4 Ų24.412%0.11613%0.13CC..Hα-helixtrans-64.6-44.8173.100000112.3M272 K390 N391 L392 G397 S398M272-A394 HydrophobicContact CE-CB 3.79Å; M272-A394 HydrophobicContact CG-CB 4.04Å; M272-A394 VanDerWaalsContact CG-O 3.3Å; M272-A394 WeakPolarHBondContact CG-O 3.44Å; M272-A394 HydrophobicContact SD-CB 4.01Å; K390-A394 WeakPolarHBondContact O-CB 3.36Å; K390-A394 PolarHBondContact O-N 2.9Å; N391-A394 PolarHBondContact O-N 3.12Å; L392-A394 VanDerWaalsContact C-N 3.31Å; L392-A394 PolarHBondContact O-N 3.39Å; A394-G397 PolarHBondContact O-N 3.06Å; A394-S398 PolarHBondContact O-N 3.49Å; A394-S398 PolarHBondContact O-OG 3.43Å
395S83.7Confident88.4Confident6 Ų625.3 Ų25.34%0.04213%0.133CC..Hα-helixtrans-66.5-43.9178.7177.80000112.6N391 L392 G397 S398 T399N391-S395 WeakPolarHBondContact O-CB 3.2Å; N391-S395 PolarHBondContact O-N 3.36Å; L392-S395 PolarHBondContact O-N 3.22Å; S395-G397 VanDerWaalsContact C-N 3.31Å; S395-S398 PolarHBondContact O-OG 3.26Å; S395-T399 PolarHBondContact O-N 2.83Å; S395-T399 PolarHBondContact O-OG1 3.26Å
396I87.2Confident88.1Confident26 Ų2628.4 Ų28.413%0.13316%0.16CC..Hα-helixtrans-61.2-46173.6-66.1165.5000109.3L213 L265 I269 L392 T399 I400L213-I396 HydrophobicContact CD1-CD1 3.99Å; L213-I396 HydrophobicContact CD1-CG1 3.35Å; L213-I396 HydrophobicContact CD2-CB 4.44Å; L213-I396 HydrophobicContact CD2-CG1 3.69Å; L213-I396 HydrophobicContact CD2-CG2 4.41Å; L213-I396 HydrophobicContact CG-CG1 4.16Å; L265-I396 HydrophobicContact CD1-CD1 4.3Å; I269-I396 HydrophobicContact CD1-CB 4.27Å; I269-I396 HydrophobicContact CD1-CG2 3.73Å; I269-I396 HydrophobicContact CG1-CB 4.19Å; I269-I396 HydrophobicContact CG1-CG2 4.03Å; L392-I396 HydrophobicContact CB-CD1 4.49Å; L392-I396 WeakPolarHBondContact O-CB 3.3Å; L392-I396 WeakPolarHBondContact O-CD1 3.26Å; L392-I396 WeakPolarHBondContact O-CG1 3.48Å; L392-I396 PolarHBondContact O-N 3.01Å; I396-T399 PolarHBondContact O-N 3.3Å; I396-I400 HydrophobicContact CG2-CD1 3.41Å; I396-I400 VanDerWaalsContact CG2-CD1 3.41Å; I396-I400 HydrophobicContact CG2-CG1 4.05Å; I396-I400 WeakPolarHBondContact O-CB 3.24Å; I396-I400 WeakPolarHBondContact O-CG1 3.47Å; I396-I400 PolarHBondContact O-N 3.4Å
397G89Confident87.9Confident0 Ų030.7 Ų30.70%017%0.171CC..Hα-helixtrans-59.6-47.2179.900000112.6G393 A394 S395 T399 I400 M401G393-G397 WeakPolarHBondContact O-CA 3.3Å; G393-G397 PolarHBondContact O-N 2.88Å; A394-G397 PolarHBondContact O-N 3.06Å; S395-G397 VanDerWaalsContact C-N 3.31Å; G397-T399 VanDerWaalsContact C-N 3.27Å; G397-T399 PolarHBondContact O-N 3.33Å; G397-I400 PolarHBondContact O-N 3.15Å; G397-M401 WeakPolarHBondContact O-CB 3.34Å; G397-M401 WeakPolarHBondContact O-CG 3.37Å; G397-M401 PolarHBondContact O-N 2.85Å
398S83.3Confident87.6Confident30 Ų3038.9 Ų38.921%0.2121%0.209CC..Hα-helixtrans-59.5-39.8177.557.50000112Y277 A394 S395 G402Y277-S398 PolarHBondContact OH-O 3.42Å; A394-S398 PolarHBondContact O-N 3.49Å; A394-S398 PolarHBondContact O-OG 3.43Å; S395-S398 PolarHBondContact O-OG 3.26Å; S398-G402 PolarHBondContact O-N 2.96Å
399T81.8Confident87.3Confident62 Ų6242.7 Ų42.738%0.3824%0.236SC..Hα-helixtrans-72.7-51179.9-57.80000112S395 I396 G397 G402 Y403S395-T399 PolarHBondContact O-N 2.83Å; S395-T399 PolarHBondContact O-OG1 3.26Å; I396-T399 PolarHBondContact O-N 3.3Å; G397-T399 VanDerWaalsContact C-N 3.27Å; G397-T399 PolarHBondContact O-N 3.33Å; T399-G402 PolarHBondContact O-N 3.36Å; T399-Y403 PolarHBondContact O-N 2.99Å
400I86.8Confident86.8Confident78 Ų7843.5 Ų43.540%0.425%0.249SC..Hα-helixtrans-64-47.5-179-67.2-179.6000110.3I396 G397 G402 Y403 L404I396-I400 HydrophobicContact CG2-CD1 3.41Å; I396-I400 VanDerWaalsContact CG2-CD1 3.41Å; I396-I400 HydrophobicContact CG2-CG1 4.05Å; I396-I400 WeakPolarHBondContact O-CB 3.24Å; I396-I400 WeakPolarHBondContact O-CG1 3.47Å; I396-I400 PolarHBondContact O-N 3.4Å; G397-I400 PolarHBondContact O-N 3.15Å; I400-G402 VanDerWaalsContact C-N 3.28Å; I400-G402 PolarHBondContact O-N 3.42Å; I400-Y403 PolarHBondContact O-N 3.08Å; I400-L404 HydrophobicContact CG2-CD1 3.9Å; I400-L404 HydrophobicContact CG2-CG 4.38Å; I400-L404 VanDerWaalsContact O-CG 3.29Å; I400-L404 WeakPolarHBondContact O-CG 3.24Å; I400-L404 PolarHBondContact O-N 2.94Å
401M89Confident86.2Confident0 Ų050.1 Ų50.10%028%0.283CS..Hα-helixtrans-67.1-32.7-179.8-60.4-59.8-179.800111.3I269 Y277 G397 L404 Y405 V419 A422 V423 I426I269-M401 HydrophobicContact CG2-CE 3.68Å; Y277-M401 HydrophobicContact CD2-CB 3.58Å; Y277-M401 VanDerWaalsContact CE2-C 3.49Å; Y277-M401 HydrophobicContact CE2-CB 3.58Å; G397-M401 WeakPolarHBondContact O-CB 3.34Å; G397-M401 WeakPolarHBondContact O-CG 3.37Å; G397-M401 PolarHBondContact O-N 2.85Å; M401-L404 PolarHBondContact O-N 3.19Å; M401-L404 HydrophobicContact SD-CD1 3.98Å; M401-Y405 VanDerWaalsContact O-CB 3.26Å; M401-Y405 WeakPolarHBondContact O-CB 3.46Å; M401-Y405 PolarHBondContact O-N 3.33Å; M401-V419 HydrophobicContact CB-CG1 4.29Å; M401-V419 HydrophobicContact CB-CG2 4.34Å; M401-V419 HydrophobicContact CG-CG1 4.3Å; M401-V419 WeakPolarHBondContact O-CG2 3.41Å; M401-V419 HydrophobicContact SD-CB 4.29Å; M401-V419 HydrophobicContact SD-CG1 3.67Å; M401-A422 HydrophobicContact CE-CB 4.46Å; M401-A422 HydrophobicContact SD-CB 4.49Å; M401-V423 HydrophobicContact CE-CG2 4.04Å; M401-I426 HydrophobicContact CE-CD1 4.4Å
402G85.3Confident85.9Confident18 Ų1854.3 Ų54.319%0.18630%0.301CS..Hα-helixtrans-66.1-42.9172.500000113.9Y277 S398 T399 I400 Y405 A406Y277-G402 WeakPolarHBondContact OH-CA 3.42Å; Y277-G402 PolarHBondContact OH-N 3.17Å; S398-G402 PolarHBondContact O-N 2.96Å; T399-G402 PolarHBondContact O-N 3.36Å; I400-G402 VanDerWaalsContact C-N 3.28Å; I400-G402 PolarHBondContact O-N 3.42Å; G402-Y405 PolarHBondContact O-N 2.92Å; G402-A406 PolarHBondContact O-N 2.95Å
403Y86Confident85.6Confident167 Ų16754.6 Ų54.666%0.65531%0.307SS*.Hα-helixtrans-60.1-49.5172.4179.6-101.4000110.8T399 I400 Y405 A406 I407T399-Y403 PolarHBondContact O-N 2.99Å; I400-Y403 PolarHBondContact O-N 3.08Å; Y403-Y405 VanDerWaalsContact C-N 3.32Å; Y403-Y405 PolarHBondContact O-N 2.93Å; Y403-A406 PolarHBondContact O-N 3.29Å; Y403-A406 VanDerWaalsContact O-N 3.1Å; Y403-I407 HydrophobicContact CD1-CD1 4.07Å; Y403-I407 HydrophobicContact CE1-CD1 3.68Å; Y403-I407 HydrophobicContact CE1-CG1 4.3Å; Y403-I407 WeakPolarHBondContact O-CG1 3.39Å; Y403-I407 PolarHBondContact O-N 3.37Å
404L90.6Very high85.4Confident35 Ų3557.1 Ų57.118%0.18332%0.324CS..Hα-helixtrans-60.2-40.1178.5-69.6172000112.7I400 M401 A406 I407 N418 V419 A422I400-L404 HydrophobicContact CG2-CD1 3.9Å; I400-L404 HydrophobicContact CG2-CG 4.38Å; I400-L404 VanDerWaalsContact O-CG 3.29Å; I400-L404 WeakPolarHBondContact O-CG 3.24Å; I400-L404 PolarHBondContact O-N 2.94Å; M401-L404 PolarHBondContact O-N 3.19Å; M401-L404 HydrophobicContact SD-CD1 3.98Å; L404-A406 VanDerWaalsContact C-N 3.3Å; L404-A406 PolarHBondContact O-N 2.97Å; L404-I407 HydrophobicContact CD2-CD1 4.24Å; L404-I407 PolarHBondContact O-N 3.31Å; L404-N418 HydrophobicContact CB-CB 4.12Å; L404-N418 VanDerWaalsContact O-CB 3.24Å; L404-N418 WeakPolarHBondContact O-CB 3.32Å; L404-N418 PolarHBondContact O-ND2 3.23Å; L404-V419 HydrophobicContact CB-CG2 4.24Å; L404-A422 HydrophobicContact CD1-CB 3.38Å
405Y89.2Confident85.4Confident18 Ų1857.8 Ų57.87%0.07133%0.325CS..Hα-helixtrans-66.1-30.8176.5-171.2-91.6000112.4Y277 V280 E284 M401 G402 Y403 I407 N415 L416 V419Y277-Y405 AromaticContact CD1-CD1 3.88Å; Y277-Y405 HydrophobicContact CD1-CD1 3.88Å; Y277-Y405 AromaticContact CD1-CD2 3.59Å; Y277-Y405 HydrophobicContact CD1-CD2 3.59Å; Y277-Y405 HydrophobicContact CD1-CE1 4.5Å; Y277-Y405 HydrophobicContact CD1-CE2 4.24Å; Y277-Y405 AromaticContact CD1-CG 3.39Å; Y277-Y405 HydrophobicContact CD1-CG 3.39Å; Y277-Y405 HydrophobicContact CE1-CD1 4.13Å; Y277-Y405 AromaticContact CE1-CG 3.91Å; Y277-Y405 HydrophobicContact CE1-CG 3.91Å; Y277-Y405 HydrophobicContact CG-CD2 4.07Å; Y277-Y405 HydrophobicContact CG-CG 4.2Å; V280-Y405 HydrophobicContact CG1-CE1 3.87Å; E284-Y405 WeakPolarHBondContact OE2-CE1 3.27Å; E284-Y405 PolarHBondContact OE2-OH 2.91Å; M401-Y405 VanDerWaalsContact O-CB 3.26Å; M401-Y405 WeakPolarHBondContact O-CB 3.46Å; M401-Y405 PolarHBondContact O-N 3.33Å; G402-Y405 PolarHBondContact O-N 2.92Å; Y403-Y405 VanDerWaalsContact C-N 3.32Å; Y403-Y405 PolarHBondContact O-N 2.93Å; Y405-I407 VanDerWaalsContact C-N 3.31Å; Y405-I407 PolarHBondContact O-N 3.45Å; Y405-N415 HydrophobicContact CD2-CB 3.99Å; Y405-N415 HydrophobicContact CE1-CB 4.45Å; Y405-N415 HydrophobicContact CE2-CB 3.74Å; Y405-N415 HydrophobicContact CG-CB 4.45Å; Y405-N415 VanDerWaalsContact O-CA 3.31Å; Y405-N415 WeakPolarHBondContact O-CA 3.48Å; Y405-N415 PolarHBondContact O-OD1 3.45Å; Y405-N415 VanDerWaalsContact O-OD1 3.04Å; Y405-L416 HydrophobicContact CE2-CB 4.29Å; Y405-V419 HydrophobicContact CD2-CG2 4.29Å
406A87.9Confident85.7Confident70 Ų7057.7 Ų57.758%0.57932%0.324SS*.Hα-helixtrans-76-17.1177.700000113.7G402 Y403 L404 Q408G402-A406 PolarHBondContact O-N 2.95Å; Y403-A406 PolarHBondContact O-N 3.29Å; Y403-A406 VanDerWaalsContact O-N 3.1Å; L404-A406 VanDerWaalsContact C-N 3.3Å; L404-A406 PolarHBondContact O-N 2.97Å; A406-Q408 PolarHBondContact O-N 2.93Å
407I88.6Confident85.9Confident48 Ų4857.5 Ų57.525%0.24632%0.323CS..  trans-73.3122.3-179.9-56.8171.3000109.6Y403 L404 Y405 S409 N415 N418Y403-I407 HydrophobicContact CD1-CD1 4.07Å; Y403-I407 HydrophobicContact CE1-CD1 3.68Å; Y403-I407 HydrophobicContact CE1-CG1 4.3Å; Y403-I407 WeakPolarHBondContact O-CG1 3.39Å; Y403-I407 PolarHBondContact O-N 3.37Å; L404-I407 HydrophobicContact CD2-CD1 4.24Å; L404-I407 PolarHBondContact O-N 3.31Å; Y405-I407 VanDerWaalsContact C-N 3.31Å; Y405-I407 PolarHBondContact O-N 3.45Å; I407-S409 VanDerWaalsContact C-N 3.33Å; I407-S409 WeakPolarHBondContact CG2-O 3.36Å; I407-N415 PolarHBondContact O-N 3.18Å; I407-N418 PolarHBondContact O-ND2 2.85Å
408Q85.7Confident86.1Confident175 Ų17558.2 Ų58.282%0.81833%0.327SS*.SBendtrans-83.5-4.7-179.3-64.3-176.8-5.300114.2A406A406-Q408 PolarHBondContact O-N 2.93Å
409S84.6Confident86.5Confident86 Ų8656.8 Ų56.860%0.60132%0.317SS*.  trans-115.6154.3173.257.90000110.5I407 N418I407-S409 VanDerWaalsContact C-N 3.33Å; I407-S409 WeakPolarHBondContact CG2-O 3.36Å; S409-N418 PolarHBondContact O-ND2 3.03Å; S409-N418 PolarHBondContact O-OD1 2.95Å
410G80.3Confident87.1Confident39 Ų3953.9 Ų53.940%0.40230%0.299SS..  trans178.2157.4-178.500000112.4F412 G413 N418G410-F412 VanDerWaalsContact C-N 3.32Å; G410-F412 PolarHBondContact O-N 3Å; G410-G413 WeakPolarHBondContact CA-O 3.42Å; G410-G413 PolarHBondContact O-N 2.94Å; G410-N418 WeakPolarHBondContact CA-OD1 3.44Å
411I76.7Confident87.4Confident155 Ų15551.1 Ų51.180%0.79529%0.286SS*.SBendtrans-61.3-42.8-177.2-62.2171.5000111.1
412F80.1Confident87.6Confident100 Ų10052.1 Ų52.144%0.43930%0.295SS..SBendtrans-103.3-2.4-179.5-63.9-80000113.2G410 H417 S421G410-F412 VanDerWaalsContact C-N 3.32Å; G410-F412 PolarHBondContact O-N 3Å; F412-H417 HydrophobicContact CB-CB 4.14Å; F412-H417 PolarHBondContact O-CD2 3.22Å; F412-S421 VanDerWaalsContact CD2-OG 3.31Å; F412-S421 WeakPolarHBondContact CD2-OG 2.97Å
413G83Confident88.1Confident19 Ų1951.3 Ų51.320%0.19629%0.286CS..  trans130.2179.2-175.300000113G410 H417 N418G410-G413 WeakPolarHBondContact CA-O 3.42Å; G410-G413 PolarHBondContact O-N 2.94Å; G413-H417 WeakPolarHBondContact O-CB 3.47Å; G413-N418 PolarHBondContact O-OD1 2.79Å
414P86.6Confident88.6Confident54 Ų5444 Ų4435%0.35126%0.261SS..SBendtrans-80.4175.6-179.933.1-36000112.9L416 H417P414-L416 PolarHBondContact O-N 3.4Å; P414-H417 PolarHBondContact O-N 3.31Å; P414-H417 PolarHBondContact O-ND1 2.76Å
415N88.4Confident88.8Confident28 Ų2847.2 Ų47.215%0.1528%0.281CS..THydrogen-bonded Turntrans59.1-118166.2-52.6-30.7000113Q285 Y405 I407 H417 N418 V419Q285-N415 PolarHBondContact NE2-ND2 3.44Å; Q285-N415 VanDerWaalsContact NE2-ND2 3.19Å; Y405-N415 HydrophobicContact CD2-CB 3.99Å; Y405-N415 HydrophobicContact CE1-CB 4.45Å; Y405-N415 HydrophobicContact CE2-CB 3.74Å; Y405-N415 HydrophobicContact CG-CB 4.45Å; Y405-N415 VanDerWaalsContact O-CA 3.31Å; Y405-N415 WeakPolarHBondContact O-CA 3.48Å; Y405-N415 PolarHBondContact O-OD1 3.45Å; Y405-N415 VanDerWaalsContact O-OD1 3.04Å; I407-N415 PolarHBondContact O-N 3.18Å; N415-H417 PolarHBondContact O-N 3.49Å; N415-H417 VanDerWaalsContact O-N 3.15Å; N415-N418 WeakPolarHBondContact O-CB 3.3Å; N415-N418 PolarHBondContact O-N 3.47Å; N415-N418 VanDerWaalsContact O-N 3.1Å; N415-V419 PolarHBondContact O-N 2.8Å
416L90.1Very high89.2Confident3 Ų347.9 Ų47.92%0.01629%0.286CS..Hα-helixtrans-58.3-29.8-177.5-17663.3000113I278 Y281 I338 Y405 P414 N418 V419 L420I278-L416 HydrophobicContact CG1-CD1 3.78Å; I278-L416 HydrophobicContact CG1-CD2 4.17Å; Y281-L416 HydrophobicContact CD1-CD2 3.49Å; Y281-L416 VanDerWaalsContact CD1-CD2 3.49Å; Y281-L416 HydrophobicContact CD2-CB 3.6Å; Y281-L416 HydrophobicContact CD2-CD2 4.12Å; Y281-L416 HydrophobicContact CE1-CD2 4.08Å; Y281-L416 HydrophobicContact CE2-CB 4.23Å; Y281-L416 HydrophobicContact CG-CB 3.78Å; Y281-L416 HydrophobicContact CG-CD2 3.51Å; Y281-L416 HydrophobicContact CG-CG 4.24Å; I338-L416 HydrophobicContact CG2-CD2 4.11Å; Y405-L416 HydrophobicContact CE2-CB 4.29Å; P414-L416 PolarHBondContact O-N 3.4Å; L416-N418 VanDerWaalsContact C-N 3.29Å; L416-N418 PolarHBondContact O-N 2.94Å; L416-V419 HydrophobicContact CD1-CB 4.35Å; L416-V419 HydrophobicContact CD1-CG1 4.4Å; L416-V419 WeakPolarHBondContact O-CB 3.37Å; L416-V419 PolarHBondContact O-N 3.34Å; L416-L420 HydrophobicContact CD1-CD1 4.38Å; L416-L420 HydrophobicContact CD1-CG 4.23Å; L416-L420 HydrophobicContact CD2-CD1 4.26Å; L416-L420 HydrophobicContact CG-CD1 3.86Å; L416-L420 HydrophobicContact CG-CG 4.18Å; L416-L420 WeakPolarHBondContact O-CG 3.37Å; L416-L420 PolarHBondContact O-N 2.9Å
417H91.4Very high89.7Confident23 Ų2344.5 Ų44.511%0.10626%0.258CS..Hα-helixtrans-65.6-34.4179.9-57.181.9000111.6S339 F412 G413 P414 N415 S421S339-H417 PolarHBondContact O-CD2 3.18Å; F412-H417 HydrophobicContact CB-CB 4.14Å; F412-H417 PolarHBondContact O-CD2 3.22Å; G413-H417 WeakPolarHBondContact O-CB 3.47Å; P414-H417 PolarHBondContact O-N 3.31Å; P414-H417 PolarHBondContact O-ND1 2.76Å; N415-H417 PolarHBondContact O-N 3.49Å; N415-H417 VanDerWaalsContact O-N 3.15Å; H417-S421 WeakPolarHBondContact O-CB 3.5Å; H417-S421 PolarHBondContact O-N 2.87Å; H417-S421 PolarHBondContact O-OG 3Å
418N92.2Very high90.1Very high15 Ų1546.3 Ų46.38%0.0827%0.267CS..Hα-helixtrans-68.4-42.3174.5-72.8-30.8000111.7L404 I407 S409 G410 G413 N415 L416 L420 S421 A422L404-N418 HydrophobicContact CB-CB 4.12Å; L404-N418 VanDerWaalsContact O-CB 3.24Å; L404-N418 WeakPolarHBondContact O-CB 3.32Å; L404-N418 PolarHBondContact O-ND2 3.23Å; I407-N418 PolarHBondContact O-ND2 2.85Å; S409-N418 PolarHBondContact O-ND2 3.03Å; S409-N418 PolarHBondContact O-OD1 2.95Å; G410-N418 WeakPolarHBondContact CA-OD1 3.44Å; G413-N418 PolarHBondContact O-OD1 2.79Å; N415-N418 WeakPolarHBondContact O-CB 3.3Å; N415-N418 PolarHBondContact O-N 3.47Å; N415-N418 VanDerWaalsContact O-N 3.1Å; L416-N418 VanDerWaalsContact C-N 3.29Å; L416-N418 PolarHBondContact O-N 2.94Å; N418-L420 PolarHBondContact O-N 2.95Å; N418-S421 PolarHBondContact O-N 3.17Å; N418-A422 PolarHBondContact O-N 2.64Å; N418-A422 VanDerWaalsContact O-N 3.08Å
419V92.7Very high90.6Very high0 Ų039.8 Ų39.80%025%0.247CC..Hα-helixtrans-57.1-50.7174.6172.60000110.1G273 Y277 M401 L404 Y405 N415 L416 S421 A422 V423G273-V419 VanDerWaalsContact CA-CG1 3.49Å; Y277-V419 HydrophobicContact CG-CG2 4.38Å; M401-V419 HydrophobicContact CB-CG1 4.29Å; M401-V419 HydrophobicContact CB-CG2 4.34Å; M401-V419 HydrophobicContact CG-CG1 4.3Å; M401-V419 WeakPolarHBondContact O-CG2 3.41Å; M401-V419 HydrophobicContact SD-CB 4.29Å; M401-V419 HydrophobicContact SD-CG1 3.67Å; L404-V419 HydrophobicContact CB-CG2 4.24Å; Y405-V419 HydrophobicContact CD2-CG2 4.29Å; N415-V419 PolarHBondContact O-N 2.8Å; L416-V419 HydrophobicContact CD1-CB 4.35Å; L416-V419 HydrophobicContact CD1-CG1 4.4Å; L416-V419 WeakPolarHBondContact O-CB 3.37Å; L416-V419 PolarHBondContact O-N 3.34Å; V419-S421 PolarHBondContact O-N 3.34Å; V419-A422 WeakPolarHBondContact O-CB 3.36Å; V419-A422 PolarHBondContact O-N 2.9Å; V419-V423 WeakPolarHBondContact O-CG2 3.44Å; V419-V423 PolarHBondContact O-N 2.99Å
420L94.5Very high91.3Very high1 Ų135.7 Ų35.71%0.00522%0.218CC..Hα-helixtrans-71.6-29.8-178.1-65.1172.2000113.4F274 I338 S339 L416 N418 A422 V423 A424F274-L420 HydrophobicContact CE1-CD2 4.34Å; F274-L420 HydrophobicContact CE2-CD2 4.45Å; F274-L420 HydrophobicContact CZ-CD2 4.06Å; I338-L420 HydrophobicContact CB-CD1 3.46Å; I338-L420 VanDerWaalsContact CB-CD1 3.46Å; I338-L420 HydrophobicContact CD1-CD1 4.47Å; I338-L420 HydrophobicContact CG2-CD1 3.27Å; S339-L420 WeakPolarHBondContact OG-CB 3.46Å; L416-L420 HydrophobicContact CD1-CD1 4.38Å; L416-L420 HydrophobicContact CD1-CG 4.23Å; L416-L420 HydrophobicContact CD2-CD1 4.26Å; L416-L420 HydrophobicContact CG-CD1 3.86Å; L416-L420 HydrophobicContact CG-CG 4.18Å; L416-L420 WeakPolarHBondContact O-CG 3.37Å; L416-L420 PolarHBondContact O-N 2.9Å; N418-L420 PolarHBondContact O-N 2.95Å; L420-A422 VanDerWaalsContact C-N 3.32Å; L420-V423 PolarHBondContact O-N 3.27Å; L420-A424 WeakPolarHBondContact O-CB 3.33Å; L420-A424 PolarHBondContact O-N 3.48Å
421S92.9Very high92.1Very high19 Ų1935.7 Ų35.713%0.13321%0.209CC..Hα-helixtrans-61.5-43.2170.6-60.40000111.1F412 H417 N418 V419 A424 V425F412-S421 VanDerWaalsContact CD2-OG 3.31Å; F412-S421 WeakPolarHBondContact CD2-OG 2.97Å; H417-S421 WeakPolarHBondContact O-CB 3.5Å; H417-S421 PolarHBondContact O-N 2.87Å; H417-S421 PolarHBondContact O-OG 3Å; N418-S421 PolarHBondContact O-N 3.17Å; V419-S421 PolarHBondContact O-N 3.34Å; S421-A424 WeakPolarHBondContact O-CB 3.25Å; S421-A424 PolarHBondContact O-N 2.87Å; S421-V425 WeakPolarHBondContact O-CG2 3.47Å; S421-V425 PolarHBondContact O-N 3.29Å
422A93.8Very high93.1Very high22 Ų2232.2 Ų32.218%0.18219%0.194CC..Hα-helixtrans-65.1-40.617500000112M401 L404 N418 V419 L420 A424 V425 I426M401-A422 HydrophobicContact CE-CB 4.46Å; M401-A422 HydrophobicContact SD-CB 4.49Å; L404-A422 HydrophobicContact CD1-CB 3.38Å; N418-A422 PolarHBondContact O-N 2.64Å; N418-A422 VanDerWaalsContact O-N 3.08Å; V419-A422 WeakPolarHBondContact O-CB 3.36Å; V419-A422 PolarHBondContact O-N 2.9Å; L420-A422 VanDerWaalsContact C-N 3.32Å; A422-A424 VanDerWaalsContact C-N 3.31Å; A422-A424 PolarHBondContact O-N 2.87Å; A422-V425 PolarHBondContact O-N 2.7Å; A422-I426 VanDerWaalsContact O-CG1 3.28Å; A422-I426 WeakPolarHBondContact O-CG1 3.44Å; A422-I426 PolarHBondContact O-N 3.46Å
423V95.6Very high93.8Very high0 Ų029.2 Ų29.20%018%0.183CC..Hα-helixtrans-59.4-42.9173.1176.40000111.3C270 F274 L331 S335 M401 V419 L420 V425 I426 S427C270-V423 HydrophobicContact CB-CG1 4.17Å; C270-V423 HydrophobicContact CB-CG2 4.17Å; F274-V423 HydrophobicContact CE2-CB 4.5Å; F274-V423 HydrophobicContact CE2-CG1 3.82Å; F274-V423 HydrophobicContact CE2-CG2 4.09Å; F274-V423 HydrophobicContact CZ-CG1 4.39Å; L331-V423 HydrophobicContact CD1-CG1 4.1Å; L331-V423 HydrophobicContact CD2-CG1 4.11Å; L331-V423 HydrophobicContact CG-CG1 3.8Å; S335-V423 WeakPolarHBondContact OG-CG1 3.26Å; M401-V423 HydrophobicContact CE-CG2 4.04Å; V419-V423 WeakPolarHBondContact O-CG2 3.44Å; V419-V423 PolarHBondContact O-N 2.99Å; L420-V423 PolarHBondContact O-N 3.27Å; V423-V425 PolarHBondContact O-N 2.77Å; V423-I426 PolarHBondContact O-N 2.68Å; V423-S427 WeakPolarHBondContact O-CB 3.47Å; V423-S427 PolarHBondContact O-N 3.21Å; V423-S427 PolarHBondContact O-OG 2.61Å
424A95.7Very high94.4Very high15 Ų1528.4 Ų28.412%0.12417%0.174CC..Hα-helixtrans-60.6-46177.500000111.3L332 L420 S421 A422 S427 I428L332-A424 HydrophobicContact CD1-CB 3.6Å; L420-A424 WeakPolarHBondContact O-CB 3.33Å; L420-A424 PolarHBondContact O-N 3.48Å; S421-A424 WeakPolarHBondContact O-CB 3.25Å; S421-A424 PolarHBondContact O-N 2.87Å; A422-A424 VanDerWaalsContact C-N 3.31Å; A422-A424 PolarHBondContact O-N 2.87Å; A424-S427 PolarHBondContact O-N 3.37Å; A424-I428 WeakPolarHBondContact O-CG1 3.25Å; A424-I428 PolarHBondContact O-N 2.74Å
425V95.7Very high94.8Very high102 Ų10229.3 Ų29.362%0.61818%0.178SC*.Hα-helixtrans-61-46176.1172.80000111.5S421 A422 V423 S427 I428 G429S421-V425 WeakPolarHBondContact O-CG2 3.47Å; S421-V425 PolarHBondContact O-N 3.29Å; A422-V425 PolarHBondContact O-N 2.7Å; V423-V425 PolarHBondContact O-N 2.77Å; V425-S427 VanDerWaalsContact C-N 3.31Å; V425-S427 PolarHBondContact O-N 3.42Å; V425-I428 PolarHBondContact O-N 2.86Å; V425-G429 PolarHBondContact O-N 3.14Å
426I96.9Very high95Very high31 Ų3132 Ų3216%0.15920%0.195CC..Hα-helixtrans-61.2-42.5177.4-68.6166.5000110.6L266 I269 C270 M401 A422 V423 I428 G429 L430L266-I426 HydrophobicContact CB-CG2 3.78Å; L266-I426 HydrophobicContact CD1-CG2 4.42Å; L266-I426 HydrophobicContact CD2-CG2 4.29Å; L266-I426 HydrophobicContact CG-CG2 4.38Å; I269-I426 HydrophobicContact CG2-CD1 3.84Å; C270-I426 VanDerWaalsContact SG-CG2 3.55Å; M401-I426 HydrophobicContact CE-CD1 4.4Å; A422-I426 VanDerWaalsContact O-CG1 3.28Å; A422-I426 WeakPolarHBondContact O-CG1 3.44Å; A422-I426 PolarHBondContact O-N 3.46Å; V423-I426 PolarHBondContact O-N 2.68Å; I426-I428 PolarHBondContact O-N 3.14Å; I426-G429 PolarHBondContact O-N 3.43Å; I426-L430 HydrophobicContact CG2-CD1 4.07Å; I426-L430 HydrophobicContact CG2-CG 4.45Å; I426-L430 WeakPolarHBondContact O-CG 3.48Å; I426-L430 PolarHBondContact O-N 3.38Å
427S97.6Very high95Very high0 Ų036.8 Ų36.80%022%0.216CC..Hα-helixtrans-63-43179.3-56.60000111.6V423 A424 V425 L430 I431V423-S427 WeakPolarHBondContact O-CB 3.47Å; V423-S427 PolarHBondContact O-N 3.21Å; V423-S427 PolarHBondContact O-OG 2.61Å; A424-S427 PolarHBondContact O-N 3.37Å; V425-S427 VanDerWaalsContact C-N 3.31Å; V425-S427 PolarHBondContact O-N 3.42Å; S427-L430 PolarHBondContact O-N 2.99Å; S427-I431 VanDerWaalsContact O-CG1 3.32Å; S427-I431 WeakPolarHBondContact O-CG1 3.38Å; S427-I431 PolarHBondContact O-N 3.32Å
428I97.4Very high95Very high86 Ų8636.7 Ų36.744%0.44122%0.216SC..Hα-helixtrans-62.2-45173.7-66.5164.5000110.4L332 A424 V425 I426 L430 I431 V432L332-I428 HydrophobicContact CD1-CD1 4.15Å; L332-I428 HydrophobicContact CD1-CG1 3.97Å; L332-I428 HydrophobicContact CD2-CG1 3.93Å; A424-I428 WeakPolarHBondContact O-CG1 3.25Å; A424-I428 PolarHBondContact O-N 2.74Å; V425-I428 PolarHBondContact O-N 2.86Å; I426-I428 PolarHBondContact O-N 3.14Å; I428-L430 VanDerWaalsContact C-N 3.32Å; I428-L430 PolarHBondContact O-N 3.41Å; I428-I431 WeakPolarHBondContact O-CB 2.77Å; I428-I431 PolarHBondContact O-N 2.84Å; I428-V432 WeakPolarHBondContact O-CG2 3.39Å; I428-V432 PolarHBondContact O-N 3.32Å
429G97.4Very high94.4Very high37 Ų3743.5 Ų43.538%0.38125%0.245SC..Hα-helixtrans-57.5-43.5176.400000112.6V425 I426 V432 L433V425-G429 PolarHBondContact O-N 3.14Å; I426-G429 PolarHBondContact O-N 3.43Å; G429-V432 PolarHBondContact O-N 3.15Å; G429-L433 VanDerWaalsContact O-CB 3.24Å; G429-L433 WeakPolarHBondContact O-CB 3.41Å; G429-L433 PolarHBondContact O-N 3.1Å
430L97.6Very high93.5Very high0 Ų047.9 Ų47.90%027%0.265CS..Hα-helixtrans-65.3-40.4176-74.3171.1000112.5T263 L266 F328 I426 S427 I428 L433 W434T263-L430 HydrophobicContact CG2-CD2 4.24Å; L266-L430 HydrophobicContact CB-CD1 4.2Å; L266-L430 HydrophobicContact CB-CD2 4.26Å; L266-L430 HydrophobicContact CB-CG 4.45Å; L266-L430 HydrophobicContact CD1-CD2 3.7Å; L266-L430 HydrophobicContact CD1-CG 4.08Å; F328-L430 HydrophobicContact CD1-CB 3.93Å; F328-L430 HydrophobicContact CD1-CD1 3.9Å; F328-L430 HydrophobicContact CD2-CB 3.87Å; F328-L430 HydrophobicContact CE1-CB 3.96Å; F328-L430 HydrophobicContact CE1-CD1 3.76Å; F328-L430 HydrophobicContact CE1-CG 4.31Å; F328-L430 HydrophobicContact CE2-CB 3.9Å; F328-L430 HydrophobicContact CG-CB 3.89Å; F328-L430 HydrophobicContact CZ-CB 3.94Å; F328-L430 HydrophobicContact CZ-CD1 4.39Å; F328-L430 HydrophobicContact CZ-CD2 4.4Å; F328-L430 HydrophobicContact CZ-CG 4.48Å; I426-L430 HydrophobicContact CG2-CD1 4.07Å; I426-L430 HydrophobicContact CG2-CG 4.45Å; I426-L430 WeakPolarHBondContact O-CG 3.48Å; I426-L430 PolarHBondContact O-N 3.38Å; S427-L430 PolarHBondContact O-N 2.99Å; I428-L430 VanDerWaalsContact C-N 3.32Å; I428-L430 PolarHBondContact O-N 3.41Å; L430-L433 HydrophobicContact CD2-CD2 4.43Å; L430-L433 PolarHBondContact O-N 2.9Å; L430-W434 WeakPolarHBondContact O-CB 3.3Å; L430-W434 PolarHBondContact O-N 3.11Å
431I97.7Very high92Very high40 Ų4056.7 Ų56.721%0.20531%0.306CS..Hα-helixtrans-58.2-52.6173.5-71166.2000110.1L325 F328 L332 S427 I428 L433 W434 V435L325-I431 HydrophobicContact CD2-CB 4.47Å; L325-I431 HydrophobicContact CD2-CG2 4.13Å; F328-I431 HydrophobicContact CB-CD1 4.07Å; F328-I431 HydrophobicContact CB-CG1 3.53Å; F328-I431 HydrophobicContact CD2-CG1 4.14Å; F328-I431 HydrophobicContact CG-CG1 4.31Å; L332-I431 HydrophobicContact CD2-CD1 4.38Å; S427-I431 VanDerWaalsContact O-CG1 3.32Å; S427-I431 WeakPolarHBondContact O-CG1 3.38Å; S427-I431 PolarHBondContact O-N 3.32Å; I428-I431 WeakPolarHBondContact O-CB 2.77Å; I428-I431 PolarHBondContact O-N 2.84Å; I431-L433 VanDerWaalsContact C-N 3.34Å; I431-L433 PolarHBondContact O-N 3.05Å; I431-W434 PolarHBondContact O-N 2.61Å; I431-V435 HydrophobicContact CG2-CG2 4.42Å; I431-V435 WeakPolarHBondContact O-CB 3.5Å; I431-V435 VanDerWaalsContact O-CG2 3.29Å; I431-V435 WeakPolarHBondContact O-CG2 3.32Å; I431-V435 PolarHBondContact O-N 2.83Å
432V96.8Very high89.8Confident82 Ų8259.9 Ų59.950%0.49733%0.329SS..Hα-helixtrans-60.4-45.8179.7173.90000110.7I428 G429 W434 V435 V436I428-V432 WeakPolarHBondContact O-CG2 3.39Å; I428-V432 PolarHBondContact O-N 3.32Å; G429-V432 PolarHBondContact O-N 3.15Å; V432-W434 PolarHBondContact O-N 3.47Å; V432-V435 PolarHBondContact O-N 2.96Å; V432-V436 HydrophobicContact CG1-CG2 4.28Å; V432-V436 WeakPolarHBondContact O-CB 3.48Å; V432-V436 WeakPolarHBondContact O-CG2 3.23Å; V432-V436 PolarHBondContact O-N 3.35Å
433L95.5Very high87.3Confident37 Ų3764.6 Ų64.619%0.19436%0.36CS..Hα-helixtrans-56.5-49.1178.6-174.774.9000111L259 I262 G429 L430 I431 F437L259-L433 HydrophobicContact CD2-CD1 4.15Å; L259-L433 HydrophobicContact CD2-CD2 3.77Å; L259-L433 HydrophobicContact CD2-CG 3.64Å; I262-L433 HydrophobicContact CB-CD2 4.38Å; I262-L433 HydrophobicContact CG2-CD2 3.72Å; G429-L433 VanDerWaalsContact O-CB 3.24Å; G429-L433 WeakPolarHBondContact O-CB 3.41Å; G429-L433 PolarHBondContact O-N 3.1Å; L430-L433 HydrophobicContact CD2-CD2 4.43Å; L430-L433 PolarHBondContact O-N 2.9Å; I431-L433 VanDerWaalsContact C-N 3.34Å; I431-L433 PolarHBondContact O-N 3.05Å; L433-F437 HydrophobicContact CD1-CD2 3.63Å; L433-F437 HydrophobicContact CD1-CE2 4Å; L433-F437 HydrophobicContact CD1-CG 4.35Å; L433-F437 HydrophobicContact CG-CD2 4.38Å; L433-F437 WeakPolarHBondContact O-CA 3.29Å; L433-F437 VanDerWaalsContact O-CB 3.26Å; L433-F437 WeakPolarHBondContact O-CB 3.39Å; L433-F437 WeakPolarHBondContact O-CD2 3.49Å; L433-F437 PolarHBondContact O-N 2.97Å
434W95.8Very high84.5Confident1 Ų172.9 Ų72.90%0.00440%0.399CS..Hα-helixtrans-71.6-34180-85.176.3000113.3T263 R320 K321 Y324 L325 F328 L430 I431 V432 F438T263-W434 PolarHBondContact OG1-NE1 3.01Å; R320-W434 HydrophobicContact CG-CZ3 4.49Å; K321-W434 WeakPolarHBondContact CE-O 2.92Å; Y324-W434 HydrophobicContact CD1-CD2 4.35Å; Y324-W434 AromaticContact CD1-CE2 3.79Å; Y324-W434 AromaticContact CD1-CH2 3.92Å; Y324-W434 HydrophobicContact CD1-CH2 3.92Å; Y324-W434 AromaticContact CD1-CZ2 3.55Å; Y324-W434 HydrophobicContact CD1-CZ2 3.55Å; Y324-W434 HydrophobicContact CD1-CZ3 4.43Å; Y324-W434 HydrophobicContact CD2-CD2 4.43Å; Y324-W434 AromaticContact CD2-CE3 3.91Å; Y324-W434 HydrophobicContact CD2-CE3 3.91Å; Y324-W434 AromaticContact CD2-CH2 3.16Å; Y324-W434 HydrophobicContact CD2-CH2 3.16Å; Y324-W434 AromaticContact CD2-CZ2 3.73Å; Y324-W434 HydrophobicContact CD2-CZ2 3.73Å; Y324-W434 AromaticContact CD2-CZ3 3.26Å; Y324-W434 HydrophobicContact CD2-CZ3 3.26Å; Y324-W434 AromaticContact CE1-CH2 3.88Å; Y324-W434 HydrophobicContact CE1-CH2 3.88Å; Y324-W434 AromaticContact CE1-CZ2 3.5Å; Y324-W434 HydrophobicContact CE1-CZ2 3.5Å; Y324-W434 AromaticContact CE2-CH2 3.15Å; Y324-W434 HydrophobicContact CE2-CH2 3.15Å; Y324-W434 AromaticContact CE2-CZ2 3.73Å; Y324-W434 HydrophobicContact CE2-CZ2 3.73Å; Y324-W434 AromaticContact CE2-CZ3 3.72Å; Y324-W434 HydrophobicContact CE2-CZ3 3.72Å; Y324-W434 AromaticContact CG-CD2 3.99Å; Y324-W434 HydrophobicContact CG-CD2 3.99Å; Y324-W434 AromaticContact CG-CE2 3.85Å; Y324-W434 AromaticContact CG-CE3 3.87Å; Y324-W434 HydrophobicContact CG-CE3 3.87Å; Y324-W434 AromaticContact CG-CH2 3.57Å; Y324-W434 HydrophobicContact CG-CH2 3.57Å; Y324-W434 AromaticContact CG-CZ2 3.65Å; Y324-W434 HydrophobicContact CG-CZ2 3.65Å; Y324-W434 AromaticContact CG-CZ3 3.67Å; Y324-W434 HydrophobicContact CG-CZ3 3.67Å; Y324-W434 AromaticContact CZ-CH2 3.5Å; Y324-W434 AromaticContact CZ-CZ2 3.59Å; L325-W434 HydrophobicContact CD2-CB 4.19Å; F328-W434 HydrophobicContact CE2-CB 4.22Å; F328-W434 AromaticContact CE2-CD1 3.35Å; F328-W434 HydrophobicContact CE2-CD2 4.28Å; F328-W434 AromaticContact CE2-CG 3.69Å; F328-W434 HydrophobicContact CE2-CG 3.69Å; F328-W434 AromaticContact CE2-NE1 3.71Å; F328-W434 AromaticContact CZ-CD1 3.68Å; F328-W434 HydrophobicContact CZ-CG 4.33Å; F328-W434 AromaticContact CZ-NE1 3.56Å; L430-W434 WeakPolarHBondContact O-CB 3.3Å; L430-W434 PolarHBondContact O-N 3.11Å; I431-W434 PolarHBondContact O-N 2.61Å; V432-W434 PolarHBondContact O-N 3.47Å; W434-F438 HydrophobicContact CD2-CB 4.35Å; W434-F438 HydrophobicContact CE3-CB 3.66Å; W434-F438 HydrophobicContact CE3-CD1 4.16Å; W434-F438 AromaticContact CE3-CD2 3.92Å; W434-F438 HydrophobicContact CE3-CD2 3.92Å; W434-F438 AromaticContact CE3-CG 3.63Å; W434-F438 HydrophobicContact CE3-CG 3.63Å; W434-F438 HydrophobicContact CH2-CD2 4.18Å; W434-F438 HydrophobicContact CH2-CE2 4.41Å; W434-F438 HydrophobicContact CZ3-CB 4.17Å; W434-F438 HydrophobicContact CZ3-CD1 4.08Å; W434-F438 AromaticContact CZ3-CD2 3.5Å; W434-F438 HydrophobicContact CZ3-CD2 3.5Å; W434-F438 HydrophobicContact CZ3-CE1 4.4Å; W434-F438 AromaticContact CZ3-CE2 3.88Å; W434-F438 HydrophobicContact CZ3-CE2 3.88Å; W434-F438 AromaticContact CZ3-CG 3.63Å; W434-F438 HydrophobicContact CZ3-CG 3.63Å; W434-F438 HydrophobicContact CZ3-CZ 4.32Å; W434-F438 WeakPolarHBondContact O-CB 3.36Å; W434-F438 PolarHBondContact O-N 2.89Å
435V94.8Very high81.7Confident73 Ų7377.2 Ų77.244%0.44243%0.428SS..Hα-helixtrans-61.7-48.1174.4168.80000110.9K321 L325 I431 V432K321-V435 PolarHBondContact NZ-O 3.06Å; L325-V435 HydrophobicContact CD1-CG2 4.22Å; L325-V435 HydrophobicContact CD2-CG2 3.86Å; I431-V435 HydrophobicContact CG2-CG2 4.42Å; I431-V435 WeakPolarHBondContact O-CB 3.5Å; I431-V435 VanDerWaalsContact O-CG2 3.29Å; I431-V435 WeakPolarHBondContact O-CG2 3.32Å; I431-V435 PolarHBondContact O-N 2.83Å; V432-V435 PolarHBondContact O-N 2.96Å
436V92.9Very high78.8Confident85 Ų8582 Ų8252%0.51544%0.441SS..Hα-helixtrans-78.8-46.4-174.5175.20000111.8V432V432-V436 HydrophobicContact CG1-CG2 4.28Å; V432-V436 WeakPolarHBondContact O-CB 3.48Å; V432-V436 WeakPolarHBondContact O-CG2 3.23Å; V432-V436 PolarHBondContact O-N 3.35Å
437F90.5Very high75.8Confident104 Ų10492.9 Ų92.946%0.45649%0.491SS..Hα-helixtrans-98-16.8-169.2-66.9-88.8000114.4R255 L259 L433 K439R255-F437 PolarHBondContact NE-O 3.47Å; R255-F437 VanDerWaalsContact NH2-CA 3.32Å; R255-F437 PolarHBondContact NH2-O 3.29Å; L259-F437 HydrophobicContact CD1-CB 4.13Å; L259-F437 HydrophobicContact CD2-CB 3.88Å; L259-F437 HydrophobicContact CG-CB 4.48Å; L433-F437 HydrophobicContact CD1-CD2 3.63Å; L433-F437 HydrophobicContact CD1-CE2 4Å; L433-F437 HydrophobicContact CD1-CG 4.35Å; L433-F437 HydrophobicContact CG-CD2 4.38Å; L433-F437 WeakPolarHBondContact O-CA 3.29Å; L433-F437 VanDerWaalsContact O-CB 3.26Å; L433-F437 WeakPolarHBondContact O-CB 3.39Å; L433-F437 WeakPolarHBondContact O-CD2 3.49Å; L433-F437 PolarHBondContact O-N 2.97Å; F437-K439 PolarHBondContact O-N 3.37Å
438F90Very high74.7Confident21 Ų2197.6 Ų97.69%0.09252%0.515CS..  trans-93108.7174.1-164.3-97.2000110.3L259 R320 K321 W434 E440L259-F438 HydrophobicContact CD1-CB 4.07Å; L259-F438 HydrophobicContact CD1-CD2 3.97Å; R320-F438 HydrophobicContact CG-CZ 4.41Å; K321-F438 HydrophobicContact CB-CD1 3.82Å; K321-F438 HydrophobicContact CB-CE1 4.11Å; K321-F438 HydrophobicContact CD-CD1 4.19Å; K321-F438 HydrophobicContact CG-CD1 4.06Å; K321-F438 PolarHBondContact NZ-O 3.2Å; W434-F438 HydrophobicContact CD2-CB 4.35Å; W434-F438 HydrophobicContact CE3-CB 3.66Å; W434-F438 HydrophobicContact CE3-CD1 4.16Å; W434-F438 AromaticContact CE3-CD2 3.92Å; W434-F438 HydrophobicContact CE3-CD2 3.92Å; W434-F438 AromaticContact CE3-CG 3.63Å; W434-F438 HydrophobicContact CE3-CG 3.63Å; W434-F438 HydrophobicContact CH2-CD2 4.18Å; W434-F438 HydrophobicContact CH2-CE2 4.41Å; W434-F438 HydrophobicContact CZ3-CB 4.17Å; W434-F438 HydrophobicContact CZ3-CD1 4.08Å; W434-F438 AromaticContact CZ3-CD2 3.5Å; W434-F438 HydrophobicContact CZ3-CD2 3.5Å; W434-F438 HydrophobicContact CZ3-CE1 4.4Å; W434-F438 AromaticContact CZ3-CE2 3.88Å; W434-F438 HydrophobicContact CZ3-CE2 3.88Å; W434-F438 AromaticContact CZ3-CG 3.63Å; W434-F438 HydrophobicContact CZ3-CG 3.63Å; W434-F438 HydrophobicContact CZ3-CZ 4.32Å; W434-F438 WeakPolarHBondContact O-CB 3.36Å; W434-F438 PolarHBondContact O-N 2.89Å; F438-E440 HydrophobicContact CE1-CB 4.4Å
439K81.5Confident73.5Confident158 Ų15898.2 Ų98.269%0.68752%0.519SS*.  trans-100114.8168-70.2-170.1179.3-1760107.8F437 Q441F437-K439 PolarHBondContact O-N 3.37Å; K439-Q441 PolarHBondContact O-N 3.23Å
440E73.1Confident72.2Confident91 Ų91101.6 Ų101.643%0.42553%0.527SS..PPolyproline II helixtrans-63.6126.9173.9-155.4138.9-128.600107.6S319 R320 F438 S442S319-E440 WeakPolarHBondContact CB-OE1 3.48Å; S319-E440 WeakPolarHBondContact CB-OE2 3.44Å; S319-E440 PolarHBondContact OG-OE1 3.13Å; S319-E440 PolarHBondContact OG-OE2 3.11Å; R320-E440 PolarHBondContact N-OE1 3.5Å; F438-E440 HydrophobicContact CE1-CB 4.4Å; E440-S442 PolarHBondContact O-N 3.01Å; E440-S442 VanDerWaalsContact O-N 3.13Å
441Q63.2Low70.7Confident186 Ų186107.5 Ų107.587%0.86956%0.558SS**PPolyproline II helixtrans-64116170.2-79.6179-2600106.3K439 S443K439-Q441 PolarHBondContact O-N 3.23Å; Q441-S443 PolarHBondContact O-N 3.22Å
442S45.6Very low69Low87 Ų87111.8 Ų111.861%0.60858%0.58SS**PPolyproline II helixtrans-55.4126.9175.547.30000108E440 Q444E440-S442 PolarHBondContact O-N 3.01Å; E440-S442 VanDerWaalsContact O-N 3.13Å; S442-Q444 PolarHBondContact O-N 3.1Å
443S42.1Very low67.1Low121 Ų121113.7 Ų113.785%0.84659%0.586SS**SBendtrans-69.132.9176.655.10000112.8Q441Q441-S443 PolarHBondContact O-N 3.22Å
444Q35.5Very low65.1Low174 Ų174119.2 Ų119.281%0.81361%0.614SS**  trans-98.318-176-81.2-172-29.600113.5S442S442-Q444 PolarHBondContact O-N 3.1Å
445S38Very low62.7Low105 Ų105128.3 Ų128.373%0.73466%0.66SS**SBendtrans-121.431.217577.50000113.9
446K34.2Very low60.1Low204 Ų204132.9 Ų132.989%0.88768%0.679SS**  trans-125.919.8172.8-83.1-163.6177.3-174.20114.2
447E34.2Very low57.1Low259 Ų259137.3 Ų137.3100%1.2169%0.694SS**  trans-97.50149.7-71.1-178.217300107.2

Retrieved 447 of 447 residues in 1451.2 ms (Link to these results)

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