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Necdin

Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Also functions as a transcription factor and directly binds to specific guanosine-rich DNA sequences.

AlphaFold DB (Q99608), UniProt , Accession X5D982, Species HUMAN (Homo sapiens, Human), Gene NDN, Length 321 aa.

Structure Viewer

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	44.3	Very low	44.8	Very low	242 Å²	242	151.6 Å²	151.6	100%	1.192	83%	0.826	S	S	*	*				0	152.8	0	-72.7	-167.4	-175.1	0	0	108.4
2	S	50.4	Low	44.3	Very low	120 Å²	120	152.3 Å²	152.3	84%	0.839	83%	0.828	S	S	*	*			trans	95.4	90	176.3	-55.8	0	0	0	0	115.3
3	E	42.7	Very low	43.7	Very low	171 Å²	171	156.5 Å²	156.5	80%	0.799	84%	0.835	S	S	*	*			trans	-60.2	147.8	166.7	-70.1	153.4	101.1	0	0	113.3
4	Q	43.8	Very low	43.4	Very low	174 Å²	174	151.6 Å²	151.6	81%	0.813	83%	0.827	S	S	*	*				63	103.4	127.4	-150.9	162.9	33.6	0	0	118.4
5	S	51.4	Low	42.9	Very low	133 Å²	133	148.1 Å²	148.1	93%	0.93	83%	0.826	S	S	*	*			trans	-122.5	131.3	152	-131.8	0	0	0	0	109.5
6	K	43	Very low	42.6	Very low	175 Å²	175	151.3 Å²	151.3	76%	0.761	83%	0.833	S	S	*	*			trans	-113	118.6	-166.2	171.6	177.8	-177.8	175.5	0	105.4
7	D	49.4	Very low	42.4	Very low	162 Å²	162	147.9 Å²	147.9	87%	0.866	83%	0.829	S	S	*	*			trans	-136	121.2	166.4	-142.7	-80.4	0	0	0	108.9
8	L	40.2	Very low	42.5	Very low	135 Å²	135	146.6 Å²	146.6	71%	0.707	83%	0.828	S	S	*	*			trans	-137.4	147.7	-167.1	-146.4	96.3	0	0	0	104.3
9	S	40.9	Very low	42.2	Very low	86 Å²	86	147.1 Å²	147.1	60%	0.601	83%	0.828	S	S	*	*			trans	80.3	134.2	167.1	-5.2	0	0	0	0	114.4
10	D	41.3	Very low	42.1	Very low	149 Å²	149	144.4 Å²	144.4	80%	0.797	82%	0.82	S	S	*	*			cis	-159.5	144.4	14	-89	-56.6	0	0	0	110.1
11	P	45.1	Very low	41.7	Very low	121 Å²	121	146.1 Å²	146.1	79%	0.786	82%	0.821	S	S	*	*			trans	-85.5	126.5	170.1	31.2	-29	0	0	0	112.4	F13	P11-F13 PolarHBondContact O-N 3.12Å
12	N	39.2	Very low	41.5	Very low	159 Å²	159	141.5 Å²	141.5	85%	0.85	81%	0.806	S	S	*	*			trans	-65	111.2	179.1	-167.4	8.7	0	0	0	111.8
13	F	36.1	Very low	41	Very low	208 Å²	208	143.8 Å²	143.8	91%	0.912	80%	0.803	S	S	*	*			trans	-106.8	90.4	175.2	-137.8	-89.6	0	0	0	108.3	P11	P11-F13 PolarHBondContact O-N 3.12Å
14	A	40.2	Very low	40.9	Very low	87 Å²	87	140.1 Å²	140.1	72%	0.719	80%	0.796	S	S	*	*			trans	-86.8	123.1	174	0	0	0	0	0	109.9
15	A	35.1	Very low	40.6	Very low	99 Å²	99	137.8 Å²	137.8	82%	0.818	80%	0.799	S	S	*	*			trans	-81.7	133.4	172.8	0	0	0	0	0	110.2
16	E	38	Very low	40.3	Very low	200 Å²	200	137.3 Å²	137.3	94%	0.935	79%	0.793	S	S	*	*			trans	-136.4	130	160.4	-156.9	151.8	104.2	0	0	109.7
17	A	40	Very low	40	Very low	93 Å²	93	132.9 Å²	132.9	77%	0.769	80%	0.797	S	S	*	*			trans	-93.4	174.7	-169	0	0	0	0	0	111.4
18	P	43.8	Very low	39.5	Very low	124 Å²	124	131 Å²	131	81%	0.805	79%	0.791	S	S	*	*			trans	-100.9	162.3	-150.7	38.9	-34.7	0	0	0	114.8
19	N	37	Very low	39.9	Very low	156 Å²	156	130.8 Å²	130.8	83%	0.834	80%	0.801	S	S	*	*			trans	-133.2	125.9	171.4	-108.3	-9.1	0	0	0	112.8
20	S	39.3	Very low	39.8	Very low	94 Å²	94	135.1 Å²	135.1	66%	0.657	81%	0.811	S	S	*	*			trans	53.2	111.4	139	-50.1	0	0	0	0	119.8
21	E	33.5	Very low	39.6	Very low	181 Å²	181	131.9 Å²	131.9	85%	0.846	81%	0.814	S	S	*	*				73.6	147.6	74.3	-72.1	-166.5	110.7	0	0	116
22	V	42.1	Very low	39.9	Very low	145 Å²	145	132.3 Å²	132.3	88%	0.879	81%	0.813	S	S	*	*			trans	95.5	134.1	167.4	-171.9	0	0	0	0	115.2
23	H	38.1	Very low	40.3	Very low	167 Å²	167	130.1 Å²	130.1	77%	0.773	81%	0.808	S	S	*	*			cis	-180	158.8	-20.9	-149.3	-104.2	0	0	0	106.6
24	S	41.1	Very low	41.1	Very low	94 Å²	94	126.3 Å²	126.3	66%	0.657	80%	0.804	S	S	*	*			trans	80.8	94.1	151.3	-55.9	0	0	0	0	122.8
25	S	37.9	Very low	41	Very low	125 Å²	125	128.1 Å²	128.1	87%	0.874	81%	0.812	S	S	*	*				41.8	156.6	109.6	-69.8	0	0	0	0	125.4
26	P	44.5	Very low	41.4	Very low	123 Å²	123	128.5 Å²	128.5	80%	0.799	81%	0.814	S	S	*	*			trans	-114.4	165.3	-147.3	41.3	-29.3	0	0	0	116.3
27	G	37.2	Very low	41.5	Very low	82 Å²	82	125.6 Å²	125.6	85%	0.845	81%	0.811	S	S	*	*			trans	-103.8	133.6	176.2	0	0	0	0	0	114.2
28	V	39.1	Very low	41.3	Very low	123 Å²	123	128.8 Å²	128.8	75%	0.745	81%	0.814	S	S	*	*			trans	-108	141.4	173.1	158.4	0	0	0	0	108.6
29	S	48.2	Very low	41.2	Very low	130 Å²	130	127.7 Å²	127.7	91%	0.909	82%	0.816	S	S	*	*			trans	-151.1	111.8	162.6	-79.1	0	0	0	0	110.8
30	E	39.2	Very low	41.2	Very low	177 Å²	177	128.7 Å²	128.7	83%	0.827	82%	0.815	S	S	*	*			trans	-88.3	144.4	168.6	-78	177.6	76.6	0	0	110.3
31	G	36.5	Very low	41.4	Very low	82 Å²	82	129.4 Å²	129.4	85%	0.845	82%	0.818	S	S	*	*			trans	-146.6	120.9	170.5	0	0	0	0	0	110.7
32	V	52.6	Low	41.9	Very low	129 Å²	129	130.3 Å²	130.3	78%	0.782	82%	0.822	S	S	*	*			trans	-107.2	152.2	-172	174.4	0	0	0	0	110.4
33	P	46	Very low	41.5	Very low	114 Å²	114	129 Å²	129	74%	0.74	82%	0.819	S	S	*	*			trans	-104.5	171.6	-174.4	39.8	-32	0	0	0	114.3
34	P	54	Low	41.9	Very low	127 Å²	127	126.4 Å²	126.4	83%	0.825	82%	0.817	S	S	*	*			trans	-125.6	142.3	163.1	34.9	-19.9	0	0	0	115.5
35	S	38.4	Very low	42.5	Very low	126 Å²	126	128.2 Å²	128.2	88%	0.881	83%	0.826	S	S	*	*			trans	-62.4	149.8	168.3	-72.9	0	0	0	0	114.1
36	A	43.9	Very low	42.4	Very low	106 Å²	106	130.7 Å²	130.7	88%	0.876	83%	0.829	S	S	*	*			trans	-127.5	139.3	164.2	0	0	0	0	0	110.9
37	T	39.3	Very low	42	Very low	140 Å²	140	128.4 Å²	128.4	86%	0.859	83%	0.827	S	S	*	*			trans	-91.3	150.2	-157.9	-67.1	0	0	0	0	114.1
38	L	35.3	Very low	42.2	Very low	160 Å²	160	130.4 Å²	130.4	84%	0.838	83%	0.826	S	S	*	*			trans	-69.3	139.8	175.8	-154.9	77.7	0	0	0	112.6
39	A	41.3	Very low	42.5	Very low	101 Å²	101	131.1 Å²	131.1	84%	0.835	83%	0.831	S	S	*	*			trans	-141.6	105.6	171	0	0	0	0	0	112
40	E	37.4	Very low	41.8	Very low	176 Å²	176	129.6 Å²	129.6	82%	0.822	83%	0.826	S	S	*	*			trans	-85.1	178.9	146.6	-93.6	176.4	70.6	0	0	108.5
41	P	44.9	Very low	42	Very low	110 Å²	110	125.8 Å²	125.8	71%	0.714	82%	0.824	S	S	*	*			cis	-135.9	172.1	6.2	36.6	-16.8	0	0	0	114.9
42	Q	42.8	Very low	42.1	Very low	200 Å²	200	127 Å²	127	94%	0.935	82%	0.817	S	S	*	*			trans	-136.6	123.3	165.5	-70.2	-170.7	-7.4	0	0	112.8
43	S	34.3	Very low	41.6	Very low	117 Å²	117	129.8 Å²	129.8	82%	0.818	82%	0.822	S	S	*	*			trans	-133.2	-178.5	166.3	-56.1	0	0	0	0	106.8
44	P	47.2	Very low	41.4	Very low	113 Å²	113	129.7 Å²	129.7	73%	0.734	83%	0.83	S	S	*	*				-117.7	-173.2	-54.7	37.1	-21.3	0	0	0	110.9
45	P	51.7	Low	40.5	Very low	131 Å²	131	128 Å²	128	85%	0.851	83%	0.828	S	S	*	*			trans	-143.5	149.3	131.8	27.4	-7.5	0	0	0	116.2
46	L	37.4	Very low	40.8	Very low	178 Å²	178	127.7 Å²	127.7	93%	0.932	82%	0.823	S	S	*	*			trans	-71.7	150.3	179.2	-66.4	142.7	0	0	0	112.9
47	G	36.6	Very low	40.9	Very low	74 Å²	74	128.1 Å²	128.1	76%	0.763	82%	0.816	S	S	*	*			trans	-150.2	131.9	170.6	0	0	0	0	0	112.2
48	P	41.1	Very low	41.1	Very low	124 Å²	124	127 Å²	127	81%	0.805	81%	0.811	S	S	*	*			trans	-98.7	166.7	-165.3	39.4	-35.2	0	0	0	112.6
49	T	45.1	Very low	41	Very low	139 Å²	139	128.6 Å²	128.6	85%	0.853	81%	0.814	S	S	*	*				-178	123.8	124.9	-69.3	0	0	0	0	109.1
50	A	33.3	Very low	41.1	Very low	97 Å²	97	128.4 Å²	128.4	80%	0.802	81%	0.813	S	S	*	*			trans	-81.1	141.7	174.9	0	0	0	0	0	110.9
51	A	42.8	Very low	41.5	Very low	97 Å²	97	125.8 Å²	125.8	80%	0.802	81%	0.811	S	S	*	*			trans	-150.8	150	153.8	0	0	0	0	0	109.9
52	P	38.6	Very low	41.1	Very low	107 Å²	107	128.3 Å²	128.3	70%	0.695	82%	0.819	S	S	*	*			trans	-112.9	155.9	-150.1	36.6	-23.8	0	0	0	115.1
53	Q	41.5	Very low	41.2	Very low	189 Å²	189	126.4 Å²	126.4	88%	0.883	82%	0.815	S	S	*	*			trans	59.9	108.6	139.4	-68.4	176.5	-50.2	0	0	120
54	A	42	Very low	41.4	Very low	111 Å²	111	130.2 Å²	130.2	92%	0.917	82%	0.82	S	S	*	*			trans	-135.7	131.9	136.2	0	0	0	0	0	108.3
55	A	36	Very low	40.9	Very low	93 Å²	93	127.8 Å²	127.8	77%	0.769	82%	0.816	S	S	*	*			trans	-134.7	-179.8	177.4	0	0	0	0	0	108.6
56	P	45.4	Very low	40.1	Very low	119 Å²	119	127.8 Å²	127.8	77%	0.773	81%	0.809	S	S	*	*				-98.4	-162	-91.1	38.4	-21.9	0	0	0	110.4
57	P	45.1	Very low	40	Very low	115 Å²	115	125.4 Å²	125.4	75%	0.747	80%	0.803	S	S	*	*			cis	-146	-146.8	15.9	40.5	-14.8	0	0	0	113.4
58	P	43.1	Very low	39.9	Very low	116 Å²	116	131 Å²	131	75%	0.753	81%	0.807	S	S	*	*				-118.3	176.8	-56.2	26.9	-6.1	0	0	0	114.5
59	Q	32.9	Very low	39.6	Very low	193 Å²	193	129.6 Å²	129.6	90%	0.902	81%	0.806	S	S	*	*			trans	-54.7	148.5	-177.8	-58.9	156	-91.9	0	0	118.8
60	A	43.8	Very low	39.1	Very low	97 Å²	97	131.7 Å²	131.7	80%	0.802	81%	0.811	S	S	*	*			trans	-173.7	156.6	134.4	0	0	0	0	0	109.4
61	P	45.1	Very low	39.2	Very low	121 Å²	121	136.2 Å²	136.2	79%	0.786	82%	0.815	S	S	*	*				-109.7	167.7	-121.9	38.1	-28	0	0	0	116.5
62	N	36.9	Very low	38.8	Very low	163 Å²	163	140.7 Å²	140.7	87%	0.872	82%	0.82	S	S	*	*			trans	-34.8	123.8	172.1	-66.8	-42.1	0	0	0	114.9
63	D	44.6	Very low	38.7	Very low	160 Å²	160	140.7 Å²	140.7	86%	0.856	83%	0.829	S	S	*	*			trans	-122.1	100.9	155.1	-149.1	-82.4	0	0	0	107.2	G65	D63-G65 PolarHBondContact O-N 3.01Å; D63-G65 VanDerWaalsContact O-N 3.12Å
64	E	39.2	Very low	38.5	Very low	197 Å²	197	136.2 Å²	136.2	92%	0.921	82%	0.824	S	S	*	*			trans	-79.3	84.4	-178.6	-171.7	149.9	72.8	0	0	108.4
65	G	35.8	Very low	38.2	Very low	63 Å²	63	140 Å²	140	65%	0.649	82%	0.822	S	S	*	*			trans	-90.4	104.9	175.5	0	0	0	0	0	111.9	D63	D63-G65 PolarHBondContact O-N 3.01Å; D63-G65 VanDerWaalsContact O-N 3.12Å
66	D	36.4	Very low	38.2	Very low	131 Å²	131	145.1 Å²	145.1	70%	0.701	83%	0.831	S	S	*	*			trans	-51.9	119.4	179.3	-154.5	-80.7	0	0	0	113	K68	D66-K68 VanDerWaalsContact C-N 3.33Å; D66-K68 PolarHBondContact O-N 3.33Å
67	P	34.7	Very low	37.7	Very low	127 Å²	127	143.3 Å²	143.3	83%	0.825	83%	0.833	S	S	*	*			trans	-84.5	74	-179.8	33.5	-32.8	0	0	0	110.7
68	K	34.3	Very low	37.3	Very low	191 Å²	191	149.8 Å²	149.8	83%	0.83	84%	0.843	S	S	*	*			trans	-128.5	68.6	166.1	-80.3	-169.5	-175.2	173.2	0	111	D66	D66-K68 VanDerWaalsContact C-N 3.33Å; D66-K68 PolarHBondContact O-N 3.33Å
69	A	35.4	Very low	37.1	Very low	95 Å²	95	147.6 Å²	147.6	79%	0.785	83%	0.834	S	S	*	*			trans	-137.1	7.6	175.9	0	0	0	0	0	115.6
70	L	34.2	Very low	37.6	Very low	183 Å²	183	147.3 Å²	147.3	96%	0.958	83%	0.833	S	S	*	*	S	Bend	trans	-105.1	20.5	-179	-89.8	163.9	0	0	0	115
71	Q	34.6	Very low	37.6	Very low	192 Å²	192	152.1 Å²	152.1	90%	0.897	84%	0.838	S	S	*	*			trans	-129.3	53	-177.6	-140.9	167.4	90.1	0	0	112.3
72	Q	36.2	Very low	37.4	Very low	192 Å²	192	150.4 Å²	150.4	90%	0.897	84%	0.835	S	S	*	*			trans	-138.4	76.3	166.9	-79.5	-177.2	-29.8	0	0	109.9
73	A	36.3	Very low	37.8	Very low	107 Å²	107	148.7 Å²	148.7	88%	0.884	83%	0.833	S	S	*	*			trans	-149.3	61.6	155.3	0	0	0	0	0	107.2
74	A	36	Very low	37.9	Very low	94 Å²	94	146.7 Å²	146.7	78%	0.777	83%	0.831	S	S	*	*			trans	-121.9	80.3	174	0	0	0	0	0	106.9
75	E	36.3	Very low	38.5	Very low	190 Å²	190	141.3 Å²	141.3	89%	0.888	82%	0.82	S	S	*	*			trans	-158.8	142.8	160.4	-111.7	169.4	166	0	0	109.7
76	E	36.9	Very low	39.1	Very low	202 Å²	202	142.8 Å²	142.8	94%	0.944	83%	0.826	S	S	*	*	S	Bend	trans	82	59.7	175.4	-55.3	-166.9	96.2	0	0	118.5
77	G	34	Very low	39.8	Very low	80 Å²	80	144.9 Å²	144.9	83%	0.825	83%	0.832	S	S	*	*			trans	-141.5	39.1	158.5	0	0	0	0	0	112.4
78	R	36.6	Very low	40.6	Very low	252 Å²	252	144.5 Å²	144.5	95%	0.951	83%	0.83	S	S	*	*			trans	-96.1	89.3	-177.3	-170.5	-174.6	-162.6	119.6	1.1	110.6
79	A	39.6	Very low	41.6	Very low	69 Å²	69	138 Å²	138	57%	0.57	82%	0.816	S	S	*	*			trans	-171.7	143	148.9	0	0	0	0	0	109.6
80	H	43.4	Very low	42.9	Very low	188 Å²	188	139.2 Å²	139.2	87%	0.87	82%	0.816	S	S	*	*			trans	87.5	41.1	173.4	-39.9	-65.2	0	0	0	117.8	A82	H80-A82 PolarHBondContact O-N 3.06Å
81	Q	42.7	Very low	44.5	Very low	197 Å²	197	134.4 Å²	134.4	92%	0.921	80%	0.803	S	S	*	*			trans	-77.3	101.5	141.9	-91.9	-174.8	13.4	0	0	107.8
82	A	41.5	Very low	46.3	Very low	86 Å²	86	130.3 Å²	130.3	71%	0.711	79%	0.793	S	S	*	*			trans	-55.3	138.7	169.3	0	0	0	0	0	109.4	H80 S84	H80-A82 PolarHBondContact O-N 3.06Å; A82-S84 PolarHBondContact O-N 2.95Å
83	P	45.4	Very low	48.2	Very low	127 Å²	127	122.1 Å²	122.1	83%	0.825	76%	0.756	S	S	*	*			trans	-59.8	119.8	-178.2	-6.9	15.3	0	0	0	109.2	A85	P83-A85 PolarHBondContact O-N 3.04Å
84	S	47.5	Very low	50.4	Low	118 Å²	118	119.3 Å²	119.3	83%	0.825	73%	0.733	S	S	*	*			trans	-39.1	114.1	170.4	-175.1	0	0	0	0	109.4	A82 A86	A82-S84 PolarHBondContact O-N 2.95Å; S84-A86 PolarHBondContact O-N 2.96Å
85	A	51	Low	52.5	Low	84 Å²	84	119.4 Å²	119.4	69%	0.694	73%	0.726	S	S	*	*			trans	-48.4	117.2	-179.8	0	0	0	0	0	108.7	P83 Q87	P83-A85 PolarHBondContact O-N 3.04Å; A85-Q87 PolarHBondContact O-N 3.04Å
86	A	48.1	Very low	54.6	Low	94 Å²	94	113.8 Å²	113.8	78%	0.777	71%	0.712	S	S	*	*			trans	-49	114.9	173.6	0	0	0	0	0	107.8	S84 P88	S84-A86 PolarHBondContact O-N 2.96Å; A86-P88 VanDerWaalsContact O-N 3.12Å
87	Q	50.8	Low	56.9	Low	175 Å²	175	108.2 Å²	108.2	82%	0.818	69%	0.686	S	S	*	*			trans	-45.7	123	174.3	-77	-79.3	-48.3	0	0	107.7	A85 G89	A85-Q87 PolarHBondContact O-N 3.04Å; Q87-G89 PolarHBondContact O-N 2.98Å
88	P	51.2	Low	59.4	Low	119 Å²	119	105.1 Å²	105.1	77%	0.773	65%	0.65	S	S	*	*	P	Polyproline II helix	trans	-55.8	117.5	-179.5	-21	30.6	0	0	0	107.5	A86	A86-P88 VanDerWaalsContact O-N 3.12Å
89	G	56.6	Low	61.8	Low	53 Å²	53	95.5 Å²	95.5	55%	0.546	62%	0.62	S	S	.	*	P	Polyproline II helix	trans	-50.7	154	177.7	0	0	0	0	0	110.3	Q87 A91	Q87-G89 PolarHBondContact O-N 2.98Å; G89-A91 PolarHBondContact O-N 3.39Å
90	P	62.8	Low	64	Low	121 Å²	121	94.1 Å²	94.1	79%	0.786	60%	0.602	S	S	*	*	S	Bend	trans	-48.1	118	-174.6	16.5	-29.7	0	0	0	110
91	A	67.6	Low	66.1	Low	82 Å²	82	86.7 Å²	86.7	68%	0.678	57%	0.566	S	S	*	*	P	Polyproline II helix	trans	-51.7	140.4	-173.1	0	0	0	0	0	110.1	G89	G89-A91 PolarHBondContact O-N 3.39Å
92	P	72.9	Confident	68.4	Low	107 Å²	107	77.3 Å²	77.3	70%	0.695	52%	0.523	S	S	*	.	P	Polyproline II helix	trans	-51.3	133.7	175.7	-26.1	33.8	0	0	0	110.6	A94	P92-A94 PolarHBondContact O-N 2.97Å
93	P	75.8	Confident	70.5	Confident	19 Å²	19	74.2 Å²	74.2	12%	0.123	49%	0.494	C	S	.	.	P	Polyproline II helix	trans	-49.4	135.8	174	-32.8	38.2	0	0	0	112.3	Q97 L98 Y132 W135	P93-Q97 HydrophobicContact CB-CB 4.4Å; P93-L98 HydrophobicContact CB-CD2 4.1Å; P93-L98 HydrophobicContact CB-CG 4.35Å; P93-Y132 HydrophobicContact CB-CD1 4.11Å; P93-Y132 HydrophobicContact CB-CE1 3.77Å; P93-Y132 HydrophobicContact CG-CD1 3.71Å; P93-Y132 HydrophobicContact CG-CE1 3.64Å; P93-W135 VanDerWaalsContact CD-CH2 3.5Å; P93-W135 HydrophobicContact CG-CD2 3.84Å; P93-W135 HydrophobicContact CG-CE3 3.88Å; P93-W135 HydrophobicContact CG-CH2 3.83Å; P93-W135 HydrophobicContact CG-CZ2 3.81Å; P93-W135 HydrophobicContact CG-CZ3 3.87Å
94	A	81.1	Confident	72.6	Confident	49 Å²	49	69.5 Å²	69.5	41%	0.405	46%	0.461	S	S	.	.	P	Polyproline II helix	trans	-59.8	146.5	173.1	0	0	0	0	0	109.7	P92 A96 Q97 L98	P92-A94 PolarHBondContact O-N 2.97Å; A94-A96 PolarHBondContact O-N 2.88Å; A94-Q97 HydrophobicContact CB-CG 4.42Å; A94-Q97 VanDerWaalsContact N-OE1 3.11Å; A94-Q97 WeakPolarHBondContact O-CB 3.49Å; A94-Q97 PolarHBondContact O-N 3.31Å; A94-L98 PolarHBondContact O-N 3.22Å
95	P	80	Confident	74.6	Confident	96 Å²	96	63.9 Å²	63.9	62%	0.623	42%	0.421	S	S	*	.	H	α-helix	trans	-51.7	-34.7	177.8	-28.7	35.2	0	0	0	113.6	Q97 L98 V99	P95-Q97 VanDerWaalsContact C-N 3.34Å; P95-Q97 PolarHBondContact O-N 3.2Å; P95-L98 PolarHBondContact O-N 3.49Å; P95-V99 WeakPolarHBondContact O-CG2 3.4Å; P95-V99 PolarHBondContact O-N 3.05Å; P95-V99 VanDerWaalsContact O-N 3.08Å
96	A	80.6	Confident	76.5	Confident	72 Å²	72	60 Å²	60	60%	0.595	39%	0.389	S	S	*	.	H	α-helix	trans	-61.5	-36.9	175.9	0	0	0	0	0	113.3	A94 V99 Q100	A94-A96 PolarHBondContact O-N 2.88Å; A96-V99 PolarHBondContact O-N 3.44Å; A96-Q100 WeakPolarHBondContact O-CB 3.41Å; A96-Q100 PolarHBondContact O-N 2.9Å
97	Q	85.3	Confident	78.3	Confident	84 Å²	84	55.7 Å²	55.7	39%	0.393	35%	0.353	S	S	.	.	H	α-helix	trans	-68.1	-38.5	177.6	-67.4	175.7	-35.9	0	0	111.6	P93 A94 P95 Q100 K101 Y132	P93-Q97 HydrophobicContact CB-CB 4.4Å; A94-Q97 HydrophobicContact CB-CG 4.42Å; A94-Q97 VanDerWaalsContact N-OE1 3.11Å; A94-Q97 WeakPolarHBondContact O-CB 3.49Å; A94-Q97 PolarHBondContact O-N 3.31Å; P95-Q97 VanDerWaalsContact C-N 3.34Å; P95-Q97 PolarHBondContact O-N 3.2Å; Q97-Q100 PolarHBondContact O-N 3.21Å; Q97-K101 WeakPolarHBondContact O-CG 3.48Å; Q97-K101 PolarHBondContact O-N 3.16Å; Q97-Y132 HydrophobicContact CB-CE1 4.25Å
98	L	87.9	Confident	80.1	Confident	15 Å²	15	47.6 Å²	47.6	8%	0.079	31%	0.314	C	S	.	.	H	α-helix	trans	-67.1	-38.3	175.9	-61.2	-177.1	0	0	0	111.7	P93 A94 P95 K101 A102 Y132 W135 I139	P93-L98 HydrophobicContact CB-CD2 4.1Å; P93-L98 HydrophobicContact CB-CG 4.35Å; A94-L98 PolarHBondContact O-N 3.22Å; P95-L98 PolarHBondContact O-N 3.49Å; L98-K101 PolarHBondContact O-N 3.03Å; L98-A102 WeakPolarHBondContact O-CB 3.06Å; L98-A102 PolarHBondContact O-N 2.93Å; L98-Y132 HydrophobicContact CD2-CD1 4.26Å; L98-W135 HydrophobicContact CD2-CB 3.63Å; L98-W135 HydrophobicContact CD2-CG 3.94Å; L98-I139 HydrophobicContact CD2-CD1 4.37Å; L98-I139 HydrophobicContact CD2-CG1 4.17Å
99	V	85.5	Confident	81.9	Confident	51 Å²	51	42 Å²	42	31%	0.309	28%	0.278	S	S	.	.	H	α-helix	trans	-63.6	-46	173.7	172.4	0	0	0	0	110.4	P95 A96 K101 A102 H103	P95-V99 WeakPolarHBondContact O-CG2 3.4Å; P95-V99 PolarHBondContact O-N 3.05Å; P95-V99 VanDerWaalsContact O-N 3.08Å; A96-V99 PolarHBondContact O-N 3.44Å; V99-K101 PolarHBondContact O-N 3.38Å; V99-A102 WeakPolarHBondContact O-CB 3.48Å; V99-A102 PolarHBondContact O-N 2.91Å; V99-A102 VanDerWaalsContact O-N 3.1Å; V99-H103 PolarHBondContact O-CD2 3.28Å; V99-H103 VanDerWaalsContact O-CD2 3.3Å; V99-H103 PolarHBondContact O-N 3.37Å
100	Q	85.5	Confident	83.3	Confident	40 Å²	40	40 Å²	40	19%	0.187	26%	0.255	C	S	.	.	H	α-helix	trans	-58.2	-46.8	175.8	-177.2	124.2	9.3	0	0	111.8	A96 Q97 A102 H103 E104	A96-Q100 WeakPolarHBondContact O-CB 3.41Å; A96-Q100 PolarHBondContact O-N 2.9Å; Q97-Q100 PolarHBondContact O-N 3.21Å; Q100-A102 VanDerWaalsContact C-N 3.27Å; Q100-A102 PolarHBondContact O-N 2.82Å; Q100-H103 PolarHBondContact O-N 2.75Å; Q100-E104 PolarHBondContact O-N 3.33Å
101	K	88.2	Confident	84.3	Confident	31 Å²	31	34.6 Å²	34.6	14%	0.135	22%	0.219	C	C	.	.	H	α-helix	trans	-62.2	-34.8	175.8	-77.5	-72.3	168.7	-162.3	0	112.9	Q97 L98 V99 H103 E104 L105 V128 Y132 I139	Q97-K101 WeakPolarHBondContact O-CG 3.48Å; Q97-K101 PolarHBondContact O-N 3.16Å; L98-K101 PolarHBondContact O-N 3.03Å; V99-K101 PolarHBondContact O-N 3.38Å; K101-H103 VanDerWaalsContact C-N 3.35Å; K101-E104 IonicContact NZ-OE2 2.93Å; K101-E104 PolarHBondContact NZ-OE2 3.33Å; K101-E104 PolarHBondContact O-N 3.12Å; K101-L105 WeakPolarHBondContact O-CB 3.47Å; K101-L105 PolarHBondContact O-N 3.3Å; K101-V128 WeakPolarHBondContact CD-O 3.38Å; K101-V128 PolarHBondContact NZ-O 2.78Å; K101-Y132 HydrophobicContact CD-CD2 4.16Å; K101-Y132 HydrophobicContact CD-CE2 4.44Å; K101-Y132 HydrophobicContact CG-CD2 4.16Å; K101-Y132 HydrophobicContact CG-CE2 4.35Å; K101-Y132 HydrophobicContact CG-CG 4.33Å; K101-I139 HydrophobicContact CB-CD1 3.86Å; K101-I139 HydrophobicContact CB-CG1 4.09Å; K101-I139 HydrophobicContact CB-CG2 4.23Å; K101-I139 HydrophobicContact CG-CD1 4.38Å
102	A	90.5	Very high	85.2	Confident	0 Å²	0	31.8 Å²	31.8	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-66.4	-38.1	176.2	0	0	0	0	0	112.3	L98 V99 Q100 L105 M106 R142 T143 I146	L98-A102 WeakPolarHBondContact O-CB 3.06Å; L98-A102 PolarHBondContact O-N 2.93Å; V99-A102 WeakPolarHBondContact O-CB 3.48Å; V99-A102 PolarHBondContact O-N 2.91Å; V99-A102 VanDerWaalsContact O-N 3.1Å; Q100-A102 VanDerWaalsContact C-N 3.27Å; Q100-A102 PolarHBondContact O-N 2.82Å; A102-L105 PolarHBondContact O-N 3.41Å; A102-M106 WeakPolarHBondContact O-CB 3.48Å; A102-M106 PolarHBondContact O-N 2.93Å; A102-R142 HydrophobicContact CB-CB 3.6Å; A102-T143 WeakPolarHBondContact CA-OG1 3.47Å; A102-T143 WeakPolarHBondContact CB-OG1 3.4Å; A102-T143 PolarHBondContact O-OG1 3.15Å; A102-I146 HydrophobicContact CB-CD1 3.82Å
103	H	87.1	Confident	85.7	Confident	22 Å²	22	29.4 Å²	29.4	10%	0.102	17%	0.173	C	C	.	.	H	α-helix	trans	-68.6	-43.6	173.3	-83	-77.6	0	0	0	112.7	V99 Q100 K101 L105 M106 W107 L217	V99-H103 PolarHBondContact O-CD2 3.28Å; V99-H103 VanDerWaalsContact O-CD2 3.3Å; V99-H103 PolarHBondContact O-N 3.37Å; Q100-H103 PolarHBondContact O-N 2.75Å; K101-H103 VanDerWaalsContact C-N 3.35Å; H103-L105 VanDerWaalsContact C-N 3.25Å; H103-L105 PolarHBondContact O-N 2.76Å; H103-M106 WeakPolarHBondContact O-CB 3.22Å; H103-M106 PolarHBondContact O-N 3.27Å; H103-W107 PolarHBondContact O-N 3.39Å; H103-W107 VanDerWaalsContact O-N 3.12Å; H103-L217 VanDerWaalsContact CB-O 3.32Å; H103-L217 WeakPolarHBondContact CB-O 3.08Å
104	E	87.8	Confident	85.8	Confident	28 Å²	28	31.3 Å²	31.3	13%	0.131	18%	0.18	C	C	.	.	H	α-helix	trans	-57.1	-43.5	173.3	-71.3	176.3	-165	0	0	110.6	Q100 K101 W107 Y108 V128	Q100-E104 PolarHBondContact O-N 3.33Å; K101-E104 IonicContact NZ-OE2 2.93Å; K101-E104 PolarHBondContact NZ-OE2 3.33Å; K101-E104 PolarHBondContact O-N 3.12Å; E104-W107 PolarHBondContact O-N 2.89Å; E104-Y108 WeakPolarHBondContact O-CB 3.45Å; E104-Y108 PolarHBondContact O-N 2.88Å; E104-V128 HydrophobicContact CB-CG1 3.82Å
105	L	90.9	Very high	85.8	Confident	0 Å²	0	34.9 Å²	34.9	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-68.1	-38.6	178.8	-178.4	58.9	0	0	0	112.7	K101 A102 H103 W107 Y108 V109 M124 V128 I139 L140 T143	K101-L105 WeakPolarHBondContact O-CB 3.47Å; K101-L105 PolarHBondContact O-N 3.3Å; A102-L105 PolarHBondContact O-N 3.41Å; H103-L105 VanDerWaalsContact C-N 3.25Å; H103-L105 PolarHBondContact O-N 2.76Å; L105-W107 VanDerWaalsContact C-N 3.35Å; L105-W107 PolarHBondContact O-N 2.83Å; L105-Y108 HydrophobicContact CD1-CD1 3.98Å; L105-Y108 PolarHBondContact O-N 2.8Å; L105-V109 HydrophobicContact CD1-CG2 3.93Å; L105-V109 HydrophobicContact CG-CG2 4.31Å; L105-V109 VanDerWaalsContact O-CG2 3.29Å; L105-V109 WeakPolarHBondContact O-CG2 3.32Å; L105-V109 PolarHBondContact O-N 3.3Å; L105-M124 HydrophobicContact CD1-CG 3.26Å; L105-M124 HydrophobicContact CD1-SD 3.6Å; L105-M124 VanDerWaalsContact CD1-SD 3.6Å; L105-M124 HydrophobicContact CD2-SD 4.1Å; L105-M124 HydrophobicContact CG-SD 4.4Å; L105-V128 HydrophobicContact CB-CG1 3.93Å; L105-V128 HydrophobicContact CD1-CB 4.32Å; L105-V128 HydrophobicContact CD1-CG1 4.41Å; L105-V128 HydrophobicContact CD1-CG2 4.32Å; L105-I139 HydrophobicContact CB-CG2 4.39Å; L105-I139 HydrophobicContact CD2-CG2 3.87Å; L105-L140 HydrophobicContact CD2-CD2 3.77Å; L105-L140 HydrophobicContact CD2-CG 4.37Å; L105-T143 HydrophobicContact CB-CG2 4.21Å; L105-T143 HydrophobicContact CD2-CG2 4.24Å; L105-T143 HydrophobicContact CG-CG2 3.96Å
106	M	89.8	Confident	85.9	Confident	3 Å²	3	39.2 Å²	39.2	2%	0.015	20%	0.196	C	C	.	.	H	α-helix	trans	-54.9	-51.7	174.2	174.3	-168.4	74.6	0	0	110.8	A102 H103 V109 L110 T143 I146 L147 F151	A102-M106 WeakPolarHBondContact O-CB 3.48Å; A102-M106 PolarHBondContact O-N 2.93Å; H103-M106 WeakPolarHBondContact O-CB 3.22Å; H103-M106 PolarHBondContact O-N 3.27Å; M106-V109 PolarHBondContact O-N 3.05Å; M106-L110 HydrophobicContact CG-CD1 3.87Å; M106-L110 WeakPolarHBondContact O-CD1 3.37Å; M106-L110 VanDerWaalsContact O-CG 3.26Å; M106-L110 WeakPolarHBondContact O-CG 3.46Å; M106-L110 PolarHBondContact O-N 3.15Å; M106-T143 HydrophobicContact CB-CG2 3.99Å; M106-I146 HydrophobicContact SD-CB 4.23Å; M106-I146 HydrophobicContact SD-CG2 3.3Å; M106-I146 WeakPolarHBondContact SD-CG2 3.39Å; M106-L147 HydrophobicContact CB-CG 4.48Å; M106-L147 HydrophobicContact CG-CD2 3.66Å; M106-L147 HydrophobicContact CG-CG 3.94Å; M106-F151 HydrophobicContact CE-CE2 4.14Å; M106-F151 HydrophobicContact CG-CE2 4.28Å; M106-F151 HydrophobicContact SD-CD2 4.17Å; M106-F151 HydrophobicContact SD-CE2 3.72Å
107	W	87.4	Confident	86.2	Confident	3 Å²	3	39.9 Å²	39.9	1%	0.011	19%	0.188	C	C	.	.	H	α-helix	trans	-63.4	-43.5	179.7	-69.2	124.4	0	0	0	112.5	H103 E104 L105 V109 L110 V111 F151 L190 L217 L219 F228	H103-W107 PolarHBondContact O-N 3.39Å; H103-W107 VanDerWaalsContact O-N 3.12Å; E104-W107 PolarHBondContact O-N 2.89Å; L105-W107 VanDerWaalsContact C-N 3.35Å; L105-W107 PolarHBondContact O-N 2.83Å; W107-V109 PolarHBondContact O-N 3.37Å; W107-L110 HydrophobicContact CE3-CD1 3.88Å; W107-L110 HydrophobicContact CZ3-CD1 4.11Å; W107-L110 PolarHBondContact O-N 3.43Å; W107-V111 PolarHBondContact O-N 2.99Å; W107-V111 VanDerWaalsContact O-N 3.15Å; W107-F151 AromaticContact CH2-CZ 3.9Å; W107-F151 HydrophobicContact CH2-CZ 3.9Å; W107-F151 HydrophobicContact CZ3-CE2 4.42Å; W107-F151 AromaticContact CZ3-CZ 3.73Å; W107-F151 HydrophobicContact CZ3-CZ 3.73Å; W107-L190 HydrophobicContact CH2-CB 4.04Å; W107-L190 HydrophobicContact CZ3-CB 4.32Å; W107-L217 PolarHBondContact NE1-O 3.49Å; W107-L217 VanDerWaalsContact NE1-O 3.17Å; W107-L219 HydrophobicContact CG-CD2 4.1Å; W107-L219 HydrophobicContact CZ2-CD1 3.98Å; W107-F228 HydrophobicContact CB-CE2 3.79Å; W107-F228 AromaticContact CD2-CE2 3.74Å; W107-F228 HydrophobicContact CD2-CE2 3.74Å; W107-F228 HydrophobicContact CD2-CZ 4.04Å; W107-F228 AromaticContact CE3-CE2 3.72Å; W107-F228 HydrophobicContact CE3-CE2 3.72Å; W107-F228 AromaticContact CE3-CZ 3.5Å; W107-F228 HydrophobicContact CE3-CZ 3.5Å; W107-F228 AromaticContact CG-CE2 3.8Å; W107-F228 HydrophobicContact CG-CE2 3.8Å; W107-F228 HydrophobicContact CG-CZ 4.49Å; W107-F228 HydrophobicContact CZ3-CZ 4.02Å
108	Y	88.2	Confident	86.2	Confident	5 Å²	5	40.6 Å²	40.6	2%	0.02	19%	0.193	C	C	.	.	H	α-helix	trans	-54.8	-49.6	176.5	171.9	-94	0	0	0	112.2	E104 L105 K112 I119 M124 D127 V128	E104-Y108 WeakPolarHBondContact O-CB 3.45Å; E104-Y108 PolarHBondContact O-N 2.88Å; L105-Y108 HydrophobicContact CD1-CD1 3.98Å; L105-Y108 PolarHBondContact O-N 2.8Å; Y108-K112 HydrophobicContact CE1-CD 3.82Å; Y108-K112 HydrophobicContact CE1-CG 4.37Å; Y108-K112 HydrophobicContact CE2-CD 4.11Å; Y108-K112 HydrophobicContact CE2-CG 4.4Å; Y108-K112 WeakPolarHBondContact O-CG 3.35Å; Y108-K112 PolarHBondContact O-N 3.08Å; Y108-K112 WeakPolarHBondContact OH-CE 3.24Å; Y108-K112 PolarHBondContact OH-NZ 3.24Å; Y108-I119 HydrophobicContact CE1-CG2 4.36Å; Y108-M124 HydrophobicContact CD1-CG 4.46Å; Y108-M124 HydrophobicContact CE1-CB 3.97Å; Y108-M124 HydrophobicContact CE1-CG 4.07Å; Y108-M124 PolarHBondContact OH-N 3.44Å; Y108-D127 HydrophobicContact CD2-CB 4.43Å; Y108-D127 HydrophobicContact CE2-CB 3.7Å; Y108-D127 WeakPolarHBondContact CE2-OD2 3.4Å; Y108-D127 PolarHBondContact OH-OD2 2.9Å; Y108-V128 HydrophobicContact CD1-CG2 3.94Å; Y108-V128 HydrophobicContact CD2-CG2 3.59Å; Y108-V128 HydrophobicContact CE1-CG2 4.46Å; Y108-V128 HydrophobicContact CE2-CG2 4.18Å; Y108-V128 HydrophobicContact CG-CG2 3.44Å; Y108-V128 VanDerWaalsContact CG-CG2 3.44Å
109	V	89.3	Confident	86.3	Confident	0 Å²	0	40 Å²	40	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-66.1	-44	-179	174.4	0	0	0	0	111	L105 M106 W107 V111 K112 D113 I119 L155 L167	L105-V109 HydrophobicContact CD1-CG2 3.93Å; L105-V109 HydrophobicContact CG-CG2 4.31Å; L105-V109 VanDerWaalsContact O-CG2 3.29Å; L105-V109 WeakPolarHBondContact O-CG2 3.32Å; L105-V109 PolarHBondContact O-N 3.3Å; M106-V109 PolarHBondContact O-N 3.05Å; W107-V109 PolarHBondContact O-N 3.37Å; V109-V111 VanDerWaalsContact C-N 3.31Å; V109-V111 PolarHBondContact O-N 2.88Å; V109-K112 PolarHBondContact O-N 3.44Å; V109-D113 WeakPolarHBondContact O-CB 3.38Å; V109-D113 PolarHBondContact O-N 3.29Å; V109-I119 HydrophobicContact CB-CD1 4.26Å; V109-I119 HydrophobicContact CG1-CD1 3.57Å; V109-I119 HydrophobicContact CG2-CG2 4.46Å; V109-L155 HydrophobicContact CG1-CD1 3.73Å; V109-L155 HydrophobicContact CG2-CD1 4.32Å; V109-L155 HydrophobicContact CG2-CD2 4.27Å; V109-L167 HydrophobicContact CG1-CD1 3.74Å; V109-L167 HydrophobicContact CG1-CD2 3.59Å; V109-L167 HydrophobicContact CG1-CG 3.53Å
110	L	85.3	Confident	86.6	Confident	13 Å²	13	43.3 Å²	43.3	7%	0.068	20%	0.197	C	C	.	.	H	α-helix	trans	-60.4	-38.9	-179.1	-71.2	164	0	0	0	112.9	M106 W107 Q114 L147 F151 L153 L167 P186	M106-L110 HydrophobicContact CG-CD1 3.87Å; M106-L110 WeakPolarHBondContact O-CD1 3.37Å; M106-L110 VanDerWaalsContact O-CG 3.26Å; M106-L110 WeakPolarHBondContact O-CG 3.46Å; M106-L110 PolarHBondContact O-N 3.15Å; W107-L110 HydrophobicContact CE3-CD1 3.88Å; W107-L110 HydrophobicContact CZ3-CD1 4.11Å; W107-L110 PolarHBondContact O-N 3.43Å; L110-Q114 PolarHBondContact O-N 2.93Å; L110-Q114 VanDerWaalsContact O-N 3.13Å; L110-L147 HydrophobicContact CD1-CD2 4.1Å; L110-L147 HydrophobicContact CD2-CD2 3.77Å; L110-L147 HydrophobicContact CG-CD2 3.77Å; L110-F151 HydrophobicContact CD1-CD1 4.29Å; L110-F151 HydrophobicContact CD1-CD2 3.76Å; L110-F151 HydrophobicContact CD1-CE1 3.96Å; L110-F151 HydrophobicContact CD1-CE2 3.4Å; L110-F151 VanDerWaalsContact CD1-CE2 3.4Å; L110-F151 HydrophobicContact CD1-CG 4.2Å; L110-F151 HydrophobicContact CD1-CZ 3.52Å; L110-F151 HydrophobicContact CD2-CD1 4.2Å; L110-F151 HydrophobicContact CD2-CD2 4.35Å; L110-F151 HydrophobicContact CD2-CG 4.09Å; L110-L153 HydrophobicContact CD2-CD1 3.72Å; L110-L167 HydrophobicContact CD2-CD1 3.87Å; L110-L167 HydrophobicContact CG-CD1 4.46Å; L110-P186 HydrophobicContact CB-CB 3.84Å
111	V	83.3	Confident	86.9	Confident	6 Å²	6	44.6 Å²	44.6	4%	0.036	20%	0.202	C	C	.	.	H	α-helix	trans	-78.5	-35.3	178.2	173.3	0	0	0	0	112.3	W107 V109 D113 Q114 K115 P186 T227 F228	W107-V111 PolarHBondContact O-N 2.99Å; W107-V111 VanDerWaalsContact O-N 3.15Å; V109-V111 VanDerWaalsContact C-N 3.31Å; V109-V111 PolarHBondContact O-N 2.88Å; V111-D113 VanDerWaalsContact C-N 3.32Å; V111-Q114 PolarHBondContact O-N 3.15Å; V111-K115 HydrophobicContact CG1-CD 4.21Å; V111-K115 HydrophobicContact CG1-CG 4.42Å; V111-K115 WeakPolarHBondContact O-CG 3.19Å; V111-K115 PolarHBondContact O-N 2.83Å; V111-P186 HydrophobicContact CB-CG 4.05Å; V111-P186 HydrophobicContact CG2-CB 3.62Å; V111-P186 HydrophobicContact CG2-CG 3.24Å; V111-T227 HydrophobicContact CB-CG2 3.13Å; V111-T227 HydrophobicContact CG1-CG2 3.58Å; V111-T227 HydrophobicContact CG2-CG2 3.25Å; V111-F228 HydrophobicContact CG2-CD1 4.39Å; V111-F228 HydrophobicContact CG2-CE1 3.92Å; V111-F228 HydrophobicContact CG2-CZ 4.05Å
112	K	87.3	Confident	87	Confident	24 Å²	24	46.8 Å²	46.8	10%	0.104	22%	0.22	C	C	.	.	H	α-helix	trans	-61	-44.8	173	-76.7	-150.7	158.4	-172.8	0	111.2	Y108 V109 Q114 K115 K116 M117 I119 D123	Y108-K112 HydrophobicContact CE1-CD 3.82Å; Y108-K112 HydrophobicContact CE1-CG 4.37Å; Y108-K112 HydrophobicContact CE2-CD 4.11Å; Y108-K112 HydrophobicContact CE2-CG 4.4Å; Y108-K112 WeakPolarHBondContact O-CG 3.35Å; Y108-K112 PolarHBondContact O-N 3.08Å; Y108-K112 WeakPolarHBondContact OH-CE 3.24Å; Y108-K112 PolarHBondContact OH-NZ 3.24Å; V109-K112 PolarHBondContact O-N 3.44Å; K112-Q114 PolarHBondContact O-N 3.3Å; K112-K115 CarbonylContact O-C 3.55Å; K112-K115 PolarHBondContact O-N 2.95Å; K112-K116 PolarHBondContact O-N 3.31Å; K112-M117 HydrophobicContact CB-CE 4.19Å; K112-M117 HydrophobicContact CD-CE 4.14Å; K112-M117 HydrophobicContact CG-CE 3.67Å; K112-M117 PolarHBondContact O-N 3.21Å; K112-I119 HydrophobicContact CB-CD1 3.97Å; K112-I119 HydrophobicContact CB-CG1 3.77Å; K112-I119 HydrophobicContact CD-CG1 4.23Å; K112-D123 IonicContact NZ-OD2 3.74Å
113	D	83.5	Confident	87	Confident	57 Å²	57	49.4 Å²	49.4	31%	0.305	23%	0.234	S	C	.	.	H	α-helix	trans	-59.8	-44.6	176.1	-171.9	80.3	0	0	0	112	V109 V111 K115 K116 L167	V109-D113 WeakPolarHBondContact O-CB 3.38Å; V109-D113 PolarHBondContact O-N 3.29Å; V111-D113 VanDerWaalsContact C-N 3.32Å; D113-K115 PolarHBondContact O-N 2.92Å; D113-K116 WeakPolarHBondContact O-CA 3.44Å; D113-K116 PolarHBondContact O-N 3.26Å; D113-L167 HydrophobicContact CB-CD1 3.79Å; D113-L167 HydrophobicContact CB-CG 4.35Å
114	Q	78.2	Confident	87.2	Confident	58 Å²	58	48.3 Å²	48.3	27%	0.271	23%	0.229	S	C	.	.	H	α-helix	trans	-59.4	-45	174.7	-178.7	-163.3	17.8	0	0	112.5	L110 V111 K112 K116 R184 P186	L110-Q114 PolarHBondContact O-N 2.93Å; L110-Q114 VanDerWaalsContact O-N 3.13Å; V111-Q114 PolarHBondContact O-N 3.15Å; K112-Q114 PolarHBondContact O-N 3.3Å; Q114-K116 PolarHBondContact O-N 3.46Å; Q114-R184 WeakPolarHBondContact CG-O 3.48Å; Q114-P186 HydrophobicContact CB-CG 4.39Å
115	K	80.8	Confident	87.4	Confident	124 Å²	124	47.8 Å²	47.8	54%	0.539	23%	0.227	S	C	.	.	T	Hydrogen-bonded Turn	trans	-70.7	4	177.3	-69.2	-177.3	176.6	-176.8	0	112.6	V111 K112 D113 M117	V111-K115 HydrophobicContact CG1-CD 4.21Å; V111-K115 HydrophobicContact CG1-CG 4.42Å; V111-K115 WeakPolarHBondContact O-CG 3.19Å; V111-K115 PolarHBondContact O-N 2.83Å; K112-K115 CarbonylContact O-C 3.55Å; K112-K115 PolarHBondContact O-N 2.95Å; D113-K115 PolarHBondContact O-N 2.92Å; K115-M117 HydrophobicContact CB-CE 4.08Å; K115-M117 HydrophobicContact CB-CG 3.71Å; K115-M117 HydrophobicContact CB-SD 4.08Å; K115-M117 HydrophobicContact CD-CE 3.92Å; K115-M117 HydrophobicContact CD-SD 4.22Å; K115-M117 PolarHBondContact O-N 2.83Å; K115-M117 VanDerWaalsContact O-N 3.13Å
116	K	81	Confident	87.4	Confident	188 Å²	188	55.6 Å²	55.6	82%	0.817	26%	0.261	S	S	*	.	T	Hydrogen-bonded Turn	trans	51.8	32.2	-174.9	-56.7	-178.1	-179.8	177.9	0	111.8	K112 D113 Q114	K112-K116 PolarHBondContact O-N 3.31Å; D113-K116 WeakPolarHBondContact O-CA 3.44Å; D113-K116 PolarHBondContact O-N 3.26Å; Q114-K116 PolarHBondContact O-N 3.46Å
117	M	86.6	Confident	87.3	Confident	85 Å²	85	59.3 Å²	59.3	42%	0.419	28%	0.281	S	S	.	.			trans	-91.4	144.2	178.9	-64	-171.4	-45.1	0	0	109.6	K112 K115	K112-M117 HydrophobicContact CB-CE 4.19Å; K112-M117 HydrophobicContact CD-CE 4.14Å; K112-M117 HydrophobicContact CG-CE 3.67Å; K112-M117 PolarHBondContact O-N 3.21Å; K115-M117 HydrophobicContact CB-CE 4.08Å; K115-M117 HydrophobicContact CB-CG 3.71Å; K115-M117 HydrophobicContact CB-SD 4.08Å; K115-M117 HydrophobicContact CD-CE 3.92Å; K115-M117 HydrophobicContact CD-SD 4.22Å; K115-M117 PolarHBondContact O-N 2.83Å; K115-M117 VanDerWaalsContact O-N 3.13Å
118	I	87.2	Confident	87.3	Confident	99 Å²	99	59.6 Å²	59.6	51%	0.508	28%	0.283	S	S	.	.			trans	-68.4	137.4	175.6	-47.6	176.9	0	0	0	109.3	W120 E164	I118-W120 VanDerWaalsContact CG2-CD1 3.41Å; I118-W120 VanDerWaalsContact CG2-NE1 3.28Å; I118-E164 HydrophobicContact CG2-CG 3.69Å
119	I	89.8	Confident	87.4	Confident	3 Å²	3	59.3 Å²	59.3	2%	0.015	28%	0.282	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-101.8	90.6	-179.3	-49.5	-179.1	0	0	0	108.7	Y108 V109 K112 F165	Y108-I119 HydrophobicContact CE1-CG2 4.36Å; V109-I119 HydrophobicContact CB-CD1 4.26Å; V109-I119 HydrophobicContact CG1-CD1 3.57Å; V109-I119 HydrophobicContact CG2-CG2 4.46Å; K112-I119 HydrophobicContact CB-CD1 3.97Å; K112-I119 HydrophobicContact CB-CG1 3.77Å; K112-I119 HydrophobicContact CD-CG1 4.23Å; I119-F165 HydrophobicContact CB-CB 4.19Å; I119-F165 WeakPolarHBondContact CB-O 3.43Å; I119-F165 HydrophobicContact CG2-CB 4.18Å; I119-F165 PolarHBondContact O-N 3.2Å
120	W	91.4	Very high	87.4	Confident	120 Å²	120	60.8 Å²	60.8	46%	0.455	30%	0.297	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-79.3	133.7	177.1	-70.1	-8.3	0	0	0	111.8	I118 D123 M124 E164	I118-W120 VanDerWaalsContact CG2-CD1 3.41Å; I118-W120 VanDerWaalsContact CG2-NE1 3.28Å; W120-D123 HydrophobicContact CB-CB 4.23Å; W120-D123 PolarHBondContact O-N 3.19Å; W120-M124 WeakPolarHBondContact O-CB 3.41Å; W120-M124 PolarHBondContact O-N 3.14Å; W120-E164 VanDerWaalsContact CD1-CG 3.5Å; W120-E164 PolarHBondContact NE1-OE1 2.91Å
121	F	91	Very high	87.5	Confident	67 Å²	67	65.1 Å²	65.1	29%	0.294	33%	0.328	S	S	.	.	H	α-helix	trans	-56.7	-44.8	176.7	-180	-97.9	0	0	0	113.1	D123 M124 V125 C136 L140 M163 F165	F121-D123 VanDerWaalsContact C-N 3.34Å; F121-D123 PolarHBondContact O-N 3.09Å; F121-M124 HydrophobicContact CD2-CE 3.35Å; F121-M124 HydrophobicContact CE2-CE 3.83Å; F121-M124 HydrophobicContact CG-CE 4.26Å; F121-M124 PolarHBondContact O-N 3.11Å; F121-V125 HydrophobicContact CD1-CG2 4.01Å; F121-V125 HydrophobicContact CD2-CG2 4.3Å; F121-V125 HydrophobicContact CE1-CG2 3.68Å; F121-V125 HydrophobicContact CE2-CG2 3.98Å; F121-V125 HydrophobicContact CG-CG2 4.32Å; F121-V125 HydrophobicContact CZ-CG2 3.66Å; F121-V125 WeakPolarHBondContact O-CB 3.41Å; F121-V125 WeakPolarHBondContact O-CG2 3.48Å; F121-V125 PolarHBondContact O-N 3.11Å; F121-C136 VanDerWaalsContact CE2-SG 3.55Å; F121-L140 HydrophobicContact CE2-CD1 3.98Å; F121-M163 HydrophobicContact CB-CB 3.81Å; F121-M163 VanDerWaalsContact CB-O 3.28Å; F121-M163 WeakPolarHBondContact CB-O 3.19Å; F121-M163 PolarHBondContact N-O 3.48Å; F121-F165 HydrophobicContact CB-CD2 4.24Å; F121-F165 HydrophobicContact CB-CE2 3.89Å; F121-F165 AromaticContact CD2-CE2 3.66Å; F121-F165 HydrophobicContact CD2-CE2 3.66Å; F121-F165 HydrophobicContact CD2-CZ 4.2Å; F121-F165 HydrophobicContact CG-CE2 4.21Å
122	P	90.8	Very high	87.7	Confident	77 Å²	77	67 Å²	67	50%	0.5	34%	0.335	S	S	.	.	H	α-helix	trans	-57.9	-44.1	176.1	-25.8	36	0	0	0	113.1	V125 K126	P122-V125 PolarHBondContact O-N 3.3Å; P122-K126 WeakPolarHBondContact O-CB 3.4Å; P122-K126 PolarHBondContact O-N 3.1Å
123	D	91.3	Very high	87.8	Confident	55 Å²	55	72.4 Å²	72.4	29%	0.294	36%	0.359	S	S	.	.	H	α-helix	trans	-65.1	-46.4	178.6	-68.4	-4.8	0	0	0	111.1	K112 W120 F121 V125 K126 D127	K112-D123 IonicContact NZ-OD2 3.74Å; W120-D123 HydrophobicContact CB-CB 4.23Å; W120-D123 PolarHBondContact O-N 3.19Å; F121-D123 VanDerWaalsContact C-N 3.34Å; F121-D123 PolarHBondContact O-N 3.09Å; D123-V125 VanDerWaalsContact C-N 3.27Å; D123-V125 PolarHBondContact O-N 3.01Å; D123-K126 PolarHBondContact O-N 3.43Å; D123-K126 VanDerWaalsContact O-N 3.12Å; D123-D127 VanDerWaalsContact O-CB 3.24Å; D123-D127 WeakPolarHBondContact O-CB 2.77Å; D123-D127 PolarHBondContact O-N 2.93Å
124	M	90.3	Very high	88.1	Confident	0 Å²	0	78.3 Å²	78.3	0%	0	38%	0.381	C	S	.	.	H	α-helix	trans	-57.2	-42.1	175.4	-178.7	-175.6	70.1	0	0	112.1	L105 Y108 W120 F121 V128 I129 L140 F165	L105-M124 HydrophobicContact CD1-CG 3.26Å; L105-M124 HydrophobicContact CD1-SD 3.6Å; L105-M124 VanDerWaalsContact CD1-SD 3.6Å; L105-M124 HydrophobicContact CD2-SD 4.1Å; L105-M124 HydrophobicContact CG-SD 4.4Å; Y108-M124 HydrophobicContact CD1-CG 4.46Å; Y108-M124 HydrophobicContact CE1-CB 3.97Å; Y108-M124 HydrophobicContact CE1-CG 4.07Å; Y108-M124 PolarHBondContact OH-N 3.44Å; W120-M124 WeakPolarHBondContact O-CB 3.41Å; W120-M124 PolarHBondContact O-N 3.14Å; F121-M124 HydrophobicContact CD2-CE 3.35Å; F121-M124 HydrophobicContact CE2-CE 3.83Å; F121-M124 HydrophobicContact CG-CE 4.26Å; F121-M124 PolarHBondContact O-N 3.11Å; M124-V128 PolarHBondContact O-N 3.27Å; M124-I129 HydrophobicContact CE-CD1 4.44Å; M124-I129 PolarHBondContact O-N 3.49Å; M124-L140 HydrophobicContact CE-CD1 4.14Å; M124-L140 HydrophobicContact CE-CD2 3.64Å; M124-L140 HydrophobicContact CE-CG 4.27Å; M124-L140 HydrophobicContact SD-CD2 3.89Å; M124-F165 HydrophobicContact CE-CE2 4.43Å
125	V	91.2	Very high	88.6	Confident	17 Å²	17	79 Å²	79	10%	0.103	38%	0.382	C	S	.	.	I	π-helix	trans	-66.5	-41.4	176.8	172.5	0	0	0	0	110.7	F121 P122 D123 I129 G130 K133	F121-V125 HydrophobicContact CD1-CG2 4.01Å; F121-V125 HydrophobicContact CD2-CG2 4.3Å; F121-V125 HydrophobicContact CE1-CG2 3.68Å; F121-V125 HydrophobicContact CE2-CG2 3.98Å; F121-V125 HydrophobicContact CG-CG2 4.32Å; F121-V125 HydrophobicContact CZ-CG2 3.66Å; F121-V125 WeakPolarHBondContact O-CB 3.41Å; F121-V125 WeakPolarHBondContact O-CG2 3.48Å; F121-V125 PolarHBondContact O-N 3.11Å; P122-V125 PolarHBondContact O-N 3.3Å; D123-V125 VanDerWaalsContact C-N 3.27Å; D123-V125 PolarHBondContact O-N 3.01Å; V125-I129 HydrophobicContact CG1-CB 4.46Å; V125-I129 HydrophobicContact CG2-CD1 4.01Å; V125-I129 CarbonylContact O-C 3.54Å; V125-I129 WeakPolarHBondContact O-CB 3.41Å; V125-I129 PolarHBondContact O-N 3.38Å; V125-G130 PolarHBondContact O-N 3.46Å; V125-K133 HydrophobicContact CG1-CD 3.88Å; V125-K133 HydrophobicContact CG1-CG 3.85Å
126	K	90.9	Very high	89.1	Confident	163 Å²	163	73.7 Å²	73.7	71%	0.709	36%	0.36	S	S	*	.	I	π-helix	trans	-69.9	-48.3	-179.7	-176.3	-176.4	175.4	-173	0	112.3	P122 D123	P122-K126 WeakPolarHBondContact O-CB 3.4Å; P122-K126 PolarHBondContact O-N 3.1Å; D123-K126 PolarHBondContact O-N 3.43Å; D123-K126 VanDerWaalsContact O-N 3.12Å
127	D	88.2	Confident	89.6	Confident	81 Å²	81	75.2 Å²	75.2	43%	0.433	36%	0.361	S	S	.	.	I	π-helix	trans	-77	-35.8	-169.5	-67.3	-8.5	0	0	0	112.5	Y108 D123	Y108-D127 HydrophobicContact CD2-CB 4.43Å; Y108-D127 HydrophobicContact CE2-CB 3.7Å; Y108-D127 WeakPolarHBondContact CE2-OD2 3.4Å; Y108-D127 PolarHBondContact OH-OD2 2.9Å; D123-D127 VanDerWaalsContact O-CB 3.24Å; D123-D127 WeakPolarHBondContact O-CB 2.77Å; D123-D127 PolarHBondContact O-N 2.93Å
128	V	88.4	Confident	89.8	Confident	9 Å²	9	73 Å²	73	6%	0.055	35%	0.354	C	S	.	.	I	π-helix	trans	-117.9	-51.1	-172.8	-174.1	0	0	0	0	112.7	K101 E104 L105 Y108 M124	K101-V128 WeakPolarHBondContact CD-O 3.38Å; K101-V128 PolarHBondContact NZ-O 2.78Å; E104-V128 HydrophobicContact CB-CG1 3.82Å; L105-V128 HydrophobicContact CB-CG1 3.93Å; L105-V128 HydrophobicContact CD1-CB 4.32Å; L105-V128 HydrophobicContact CD1-CG1 4.41Å; L105-V128 HydrophobicContact CD1-CG2 4.32Å; Y108-V128 HydrophobicContact CD1-CG2 3.94Å; Y108-V128 HydrophobicContact CD2-CG2 3.59Å; Y108-V128 HydrophobicContact CE1-CG2 4.46Å; Y108-V128 HydrophobicContact CE2-CG2 4.18Å; Y108-V128 HydrophobicContact CG-CG2 3.44Å; Y108-V128 VanDerWaalsContact CG-CG2 3.44Å; M124-V128 PolarHBondContact O-N 3.27Å
129	I	89.9	Confident	90	Very high	0 Å²	0	68.3 Å²	68.3	0%	0	33%	0.33	C	S	.	.	I	π-helix	trans	-72.4	-41.7	-171.3	-56.9	-177	0	0	0	110.5	M124 V125 S131 Y132 C136 I139	M124-I129 HydrophobicContact CE-CD1 4.44Å; M124-I129 PolarHBondContact O-N 3.49Å; V125-I129 HydrophobicContact CG1-CB 4.46Å; V125-I129 HydrophobicContact CG2-CD1 4.01Å; V125-I129 CarbonylContact O-C 3.54Å; V125-I129 WeakPolarHBondContact O-CB 3.41Å; V125-I129 PolarHBondContact O-N 3.38Å; I129-S131 PolarHBondContact O-N 2.94Å; I129-Y132 VanDerWaalsContact CG2-C 3.44Å; I129-Y132 WeakPolarHBondContact CG2-O 3.45Å; I129-Y132 WeakPolarHBondContact O-CB 3.34Å; I129-Y132 WeakPolarHBondContact O-CD2 3.45Å; I129-Y132 PolarHBondContact O-N 3.37Å; I129-C136 HydrophobicContact CD1-CB 4.05Å; I129-C136 WeakPolarHBondContact CD1-SG 3.16Å; I129-C136 HydrophobicContact CG2-CB 4.42Å; I129-I139 HydrophobicContact CG2-CD1 4.13Å
130	G	88.9	Confident	90.1	Very high	30 Å²	30	69.6 Å²	69.6	31%	0.309	34%	0.336	S	S	.	.	G	3₁₀ helix	trans	55.2	-118.7	175.6	0	0	0	0	0	112.4	V125 Y132 K133	V125-G130 PolarHBondContact O-N 3.46Å; G130-Y132 PolarHBondContact O-N 3.19Å; G130-K133 WeakPolarHBondContact O-CE 3.48Å; G130-K133 WeakPolarHBondContact O-CG 3.43Å
131	S	87.4	Confident	90.1	Very high	104 Å²	104	73.7 Å²	73.7	73%	0.727	35%	0.352	S	S	*	.	G	3₁₀ helix	trans	-70.4	-12.2	178.7	54.9	0	0	0	0	114.3	I129 K133	I129-S131 PolarHBondContact O-N 2.94Å; S131-K133 PolarHBondContact O-N 3.19Å
132	Y	87.4	Confident	90.1	Very high	46 Å²	46	75.2 Å²	75.2	18%	0.18	36%	0.356	C	S	.	.	G	3₁₀ helix	trans	-86.5	21.6	-176.8	-62.4	-97.9	0	0	0	113.6	P93 Q97 L98 K101 I129 G130 K134 W135 C136	P93-Y132 HydrophobicContact CB-CD1 4.11Å; P93-Y132 HydrophobicContact CB-CE1 3.77Å; P93-Y132 HydrophobicContact CG-CD1 3.71Å; P93-Y132 HydrophobicContact CG-CE1 3.64Å; Q97-Y132 HydrophobicContact CB-CE1 4.25Å; L98-Y132 HydrophobicContact CD2-CD1 4.26Å; K101-Y132 HydrophobicContact CD-CD2 4.16Å; K101-Y132 HydrophobicContact CD-CE2 4.44Å; K101-Y132 HydrophobicContact CG-CD2 4.16Å; K101-Y132 HydrophobicContact CG-CE2 4.35Å; K101-Y132 HydrophobicContact CG-CG 4.33Å; I129-Y132 VanDerWaalsContact CG2-C 3.44Å; I129-Y132 WeakPolarHBondContact CG2-O 3.45Å; I129-Y132 WeakPolarHBondContact O-CB 3.34Å; I129-Y132 WeakPolarHBondContact O-CD2 3.45Å; I129-Y132 PolarHBondContact O-N 3.37Å; G130-Y132 PolarHBondContact O-N 3.19Å; Y132-K134 VanDerWaalsContact C-N 3.26Å; Y132-K134 PolarHBondContact O-N 2.96Å; Y132-K134 VanDerWaalsContact O-N 3.16Å; Y132-W135 HydrophobicContact CD1-CE3 4.23Å; Y132-W135 CarbonylContact O-C 3.58Å; Y132-W135 WeakPolarHBondContact O-CA 3.37Å; Y132-W135 PolarHBondContact O-N 3.14Å; Y132-C136 PolarHBondContact O-N 3.34Å
133	K	88.9	Confident	90.2	Very high	137 Å²	137	71.6 Å²	71.6	60%	0.596	33%	0.332	S	S	*	.	G	3₁₀ helix	trans	-54	-39.1	-174.2	-53.8	-166.8	-179.4	177.7	0	113.2	V125 G130 S131 W135 C136	V125-K133 HydrophobicContact CG1-CD 3.88Å; V125-K133 HydrophobicContact CG1-CG 3.85Å; G130-K133 WeakPolarHBondContact O-CE 3.48Å; G130-K133 WeakPolarHBondContact O-CG 3.43Å; S131-K133 PolarHBondContact O-N 3.19Å; K133-W135 PolarHBondContact O-N 3.28Å; K133-C136 WeakPolarHBondContact O-CB 3.38Å; K133-C136 PolarHBondContact O-N 3.41Å
134	K	90	Very high	90	Very high	181 Å²	181	70.3 Å²	70.3	79%	0.787	33%	0.327	S	S	*	.	G	3₁₀ helix	trans	-60.3	-28.4	177.8	-61.8	-178.3	-179.5	179.8	0	112.7	Y132	Y132-K134 VanDerWaalsContact C-N 3.26Å; Y132-K134 PolarHBondContact O-N 2.96Å; Y132-K134 VanDerWaalsContact O-N 3.16Å
135	W	90.5	Very high	89.9	Confident	74 Å²	74	74.2 Å²	74.2	28%	0.28	35%	0.348	S	S	.	.	G	3₁₀ helix	trans	-102.2	11.4	179	-53.6	-90.7	0	0	0	112.6	P93 L98 Y132 K133 R137 S138 I139	P93-W135 VanDerWaalsContact CD-CH2 3.5Å; P93-W135 HydrophobicContact CG-CD2 3.84Å; P93-W135 HydrophobicContact CG-CE3 3.88Å; P93-W135 HydrophobicContact CG-CH2 3.83Å; P93-W135 HydrophobicContact CG-CZ2 3.81Å; P93-W135 HydrophobicContact CG-CZ3 3.87Å; L98-W135 HydrophobicContact CD2-CB 3.63Å; L98-W135 HydrophobicContact CD2-CG 3.94Å; Y132-W135 HydrophobicContact CD1-CE3 4.23Å; Y132-W135 CarbonylContact O-C 3.58Å; Y132-W135 WeakPolarHBondContact O-CA 3.37Å; Y132-W135 PolarHBondContact O-N 3.14Å; K133-W135 PolarHBondContact O-N 3.28Å; W135-R137 VanDerWaalsContact C-N 3.3Å; W135-R137 PolarHBondContact O-N 3.32Å; W135-S138 WeakPolarHBondContact O-CA 3.35Å; W135-S138 WeakPolarHBondContact O-CB 3.35Å; W135-S138 PolarHBondContact O-N 3.34Å; W135-I139 HydrophobicContact CB-CD1 4.5Å; W135-I139 WeakPolarHBondContact O-CG1 3.49Å; W135-I139 PolarHBondContact O-N 3.31Å
136	C	90.9	Very high	89.5	Confident	12 Å²	12	74.5 Å²	74.5	8%	0.081	35%	0.348	C	S	.	.	H	α-helix	trans	-51.4	-47.2	-179	176.5	0	0	0	0	112.1	F121 I129 Y132 K133 S138 I139 L140	F121-C136 VanDerWaalsContact CE2-SG 3.55Å; I129-C136 HydrophobicContact CD1-CB 4.05Å; I129-C136 WeakPolarHBondContact CD1-SG 3.16Å; I129-C136 HydrophobicContact CG2-CB 4.42Å; Y132-C136 PolarHBondContact O-N 3.34Å; K133-C136 WeakPolarHBondContact O-CB 3.38Å; K133-C136 PolarHBondContact O-N 3.41Å; C136-S138 VanDerWaalsContact C-N 3.29Å; C136-S138 PolarHBondContact O-N 3.34Å; C136-I139 PolarHBondContact O-N 3.24Å; C136-L140 WeakPolarHBondContact O-CB 3.43Å; C136-L140 WeakPolarHBondContact O-CG 3.32Å; C136-L140 PolarHBondContact O-N 3.31Å
137	R	90.7	Very high	89.2	Confident	219 Å²	219	66.8 Å²	66.8	83%	0.826	32%	0.315	S	S	*	.	H	α-helix	trans	-57.9	-40.4	176.4	-176.4	179	177.1	-172.9	0.2	112.8	W135 R141	W135-R137 VanDerWaalsContact C-N 3.3Å; W135-R137 PolarHBondContact O-N 3.32Å; R137-R141 WeakPolarHBondContact O-CB 3.49Å; R137-R141 PolarHBondContact O-N 2.97Å
138	S	91.6	Very high	88.9	Confident	40 Å²	40	64.3 Å²	64.3	28%	0.28	31%	0.306	S	S	.	.	H	α-helix	trans	-68.6	-44.2	178.6	-176.2	0	0	0	0	111.2	W135 C136 R141 R142	W135-S138 WeakPolarHBondContact O-CA 3.35Å; W135-S138 WeakPolarHBondContact O-CB 3.35Å; W135-S138 PolarHBondContact O-N 3.34Å; C136-S138 VanDerWaalsContact C-N 3.29Å; C136-S138 PolarHBondContact O-N 3.34Å; S138-R141 PolarHBondContact O-N 2.93Å; S138-R142 WeakPolarHBondContact O-CB 3.28Å; S138-R142 VanDerWaalsContact O-CG 3.29Å; S138-R142 WeakPolarHBondContact O-CG 3.34Å; S138-R142 PolarHBondContact O-N 2.84Å
139	I	91.8	Very high	88.2	Confident	0 Å²	0	68.7 Å²	68.7	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-61.2	-50.2	176.6	-65.8	166.1	0	0	0	109.7	L98 K101 L105 I129 W135 C136 R141 R142 T143	L98-I139 HydrophobicContact CD2-CD1 4.37Å; L98-I139 HydrophobicContact CD2-CG1 4.17Å; K101-I139 HydrophobicContact CB-CD1 3.86Å; K101-I139 HydrophobicContact CB-CG1 4.09Å; K101-I139 HydrophobicContact CB-CG2 4.23Å; K101-I139 HydrophobicContact CG-CD1 4.38Å; L105-I139 HydrophobicContact CB-CG2 4.39Å; L105-I139 HydrophobicContact CD2-CG2 3.87Å; I129-I139 HydrophobicContact CG2-CD1 4.13Å; W135-I139 HydrophobicContact CB-CD1 4.5Å; W135-I139 WeakPolarHBondContact O-CG1 3.49Å; W135-I139 PolarHBondContact O-N 3.31Å; C136-I139 PolarHBondContact O-N 3.24Å; I139-R141 PolarHBondContact O-N 3.32Å; I139-R142 PolarHBondContact O-N 3.17Å; I139-R142 VanDerWaalsContact O-N 3.17Å; I139-T143 WeakPolarHBondContact O-CB 3.48Å; I139-T143 PolarHBondContact O-N 2.91Å; I139-T143 PolarHBondContact O-OG1 3.5Å; I139-T143 VanDerWaalsContact O-OG1 3.05Å
140	L	91.3	Very high	87.4	Confident	29 Å²	29	69.2 Å²	69.2	15%	0.152	32%	0.324	C	S	.	.	H	α-helix	trans	-58.7	-46.4	178.4	-79.8	170.5	0	0	0	113	L105 F121 M124 C136 R142 T143 S144 L155	L105-L140 HydrophobicContact CD2-CD2 3.77Å; L105-L140 HydrophobicContact CD2-CG 4.37Å; F121-L140 HydrophobicContact CE2-CD1 3.98Å; M124-L140 HydrophobicContact CE-CD1 4.14Å; M124-L140 HydrophobicContact CE-CD2 3.64Å; M124-L140 HydrophobicContact CE-CG 4.27Å; M124-L140 HydrophobicContact SD-CD2 3.89Å; C136-L140 WeakPolarHBondContact O-CB 3.43Å; C136-L140 WeakPolarHBondContact O-CG 3.32Å; C136-L140 PolarHBondContact O-N 3.31Å; L140-R142 VanDerWaalsContact C-N 3.3Å; L140-R142 PolarHBondContact O-N 3.43Å; L140-T143 PolarHBondContact O-N 2.78Å; L140-S144 WeakPolarHBondContact O-CB 3.46Å; L140-S144 PolarHBondContact O-N 2.97Å; L140-L155 HydrophobicContact CD2-CD2 3.71Å
141	R	91.5	Very high	86.6	Confident	206 Å²	206	68.9 Å²	68.9	78%	0.777	32%	0.315	S	S	*	.	H	α-helix	trans	-59.7	-43.6	177	-175.1	-179.9	179.8	-175	1.6	111.2	R137 S138 I139 L145	R137-R141 WeakPolarHBondContact O-CB 3.49Å; R137-R141 PolarHBondContact O-N 2.97Å; S138-R141 PolarHBondContact O-N 2.93Å; I139-R141 PolarHBondContact O-N 3.32Å; R141-L145 WeakPolarHBondContact O-CB 3.44Å; R141-L145 PolarHBondContact O-N 2.95Å; R141-L145 VanDerWaalsContact O-N 3.15Å
142	R	91.3	Very high	86	Confident	100 Å²	100	64.2 Å²	64.2	38%	0.377	28%	0.283	S	S	.	.	H	α-helix	trans	-67.2	-44.2	177.6	-72.6	174.8	-176.3	-83.5	0.1	111.4	A102 S138 I139 L140 S144 L145 I146	A102-R142 HydrophobicContact CB-CB 3.6Å; S138-R142 WeakPolarHBondContact O-CB 3.28Å; S138-R142 VanDerWaalsContact O-CG 3.29Å; S138-R142 WeakPolarHBondContact O-CG 3.34Å; S138-R142 PolarHBondContact O-N 2.84Å; I139-R142 PolarHBondContact O-N 3.17Å; I139-R142 VanDerWaalsContact O-N 3.17Å; L140-R142 VanDerWaalsContact C-N 3.3Å; L140-R142 PolarHBondContact O-N 3.43Å; R142-S144 PolarHBondContact O-N 3.04Å; R142-L145 WeakPolarHBondContact O-CB 3.47Å; R142-L145 PolarHBondContact O-N 3.12Å; R142-I146 VanDerWaalsContact O-CG1 3.26Å; R142-I146 WeakPolarHBondContact O-CG1 3.4Å; R142-I146 PolarHBondContact O-N 3.46Å
143	T	91.5	Very high	85.8	Confident	0 Å²	0	63.7 Å²	63.7	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-60.7	-46.6	177.4	-62.7	0	0	0	0	111.6	A102 L105 M106 I139 L140 L145 I146 L147	A102-T143 WeakPolarHBondContact CA-OG1 3.47Å; A102-T143 WeakPolarHBondContact CB-OG1 3.4Å; A102-T143 PolarHBondContact O-OG1 3.15Å; L105-T143 HydrophobicContact CB-CG2 4.21Å; L105-T143 HydrophobicContact CD2-CG2 4.24Å; L105-T143 HydrophobicContact CG-CG2 3.96Å; M106-T143 HydrophobicContact CB-CG2 3.99Å; I139-T143 WeakPolarHBondContact O-CB 3.48Å; I139-T143 PolarHBondContact O-N 2.91Å; I139-T143 PolarHBondContact O-OG1 3.5Å; I139-T143 VanDerWaalsContact O-OG1 3.05Å; L140-T143 PolarHBondContact O-N 2.78Å; T143-L145 VanDerWaalsContact C-N 3.25Å; T143-L145 PolarHBondContact O-N 3.34Å; T143-I146 PolarHBondContact O-N 3.12Å; T143-I146 VanDerWaalsContact O-N 3.14Å; T143-L147 HydrophobicContact CG2-CD1 3.76Å; T143-L147 HydrophobicContact CG2-CG 4.24Å; T143-L147 WeakPolarHBondContact O-CB 3.25Å; T143-L147 WeakPolarHBondContact O-CG 3.3Å; T143-L147 PolarHBondContact O-N 2.87Å
144	S	88.4	Confident	85.5	Confident	28 Å²	28	60.2 Å²	60.2	20%	0.196	27%	0.269	C	S	.	.	H	α-helix	trans	-58.8	-39.7	176.4	-173.8	0	0	0	0	111.6	L140 R142 A148	L140-S144 WeakPolarHBondContact O-CB 3.46Å; L140-S144 PolarHBondContact O-N 2.97Å; R142-S144 PolarHBondContact O-N 3.04Å; S144-A148 WeakPolarHBondContact O-CB 3.46Å; S144-A148 PolarHBondContact O-N 3.26Å
145	L	87.3	Confident	85.5	Confident	83 Å²	83	52.4 Å²	52.4	44%	0.435	24%	0.236	S	C	.	.	H	α-helix	trans	-67	-39.4	175.9	-176.1	62.3	0	0	0	113	R141 R142 T143 R149	R141-L145 WeakPolarHBondContact O-CB 3.44Å; R141-L145 PolarHBondContact O-N 2.95Å; R141-L145 VanDerWaalsContact O-N 3.15Å; R142-L145 WeakPolarHBondContact O-CB 3.47Å; R142-L145 PolarHBondContact O-N 3.12Å; T143-L145 VanDerWaalsContact C-N 3.25Å; T143-L145 PolarHBondContact O-N 3.34Å; L145-R149 WeakPolarHBondContact O-CB 3.43Å; L145-R149 WeakPolarHBondContact O-CD 3.35Å; L145-R149 WeakPolarHBondContact O-CG 3.04Å; L145-R149 PolarHBondContact O-N 3.22Å
146	I	83.3	Confident	85.3	Confident	23 Å²	23	56 Å²	56	12%	0.118	25%	0.249	C	C	.	.	H	α-helix	trans	-69.8	-44.7	176.8	-59.7	160.9	0	0	0	109.9	A102 M106 R142 T143 A148 R149 V150	A102-I146 HydrophobicContact CB-CD1 3.82Å; M106-I146 HydrophobicContact SD-CB 4.23Å; M106-I146 HydrophobicContact SD-CG2 3.3Å; M106-I146 WeakPolarHBondContact SD-CG2 3.39Å; R142-I146 VanDerWaalsContact O-CG1 3.26Å; R142-I146 WeakPolarHBondContact O-CG1 3.4Å; R142-I146 PolarHBondContact O-N 3.46Å; T143-I146 PolarHBondContact O-N 3.12Å; T143-I146 VanDerWaalsContact O-N 3.14Å; I146-A148 VanDerWaalsContact C-N 3.33Å; I146-A148 PolarHBondContact O-N 2.92Å; I146-R149 PolarHBondContact O-N 3.21Å; I146-R149 VanDerWaalsContact O-N 3.15Å; I146-V150 HydrophobicContact CG2-CG2 3.81Å; I146-V150 WeakPolarHBondContact O-CB 3.47Å; I146-V150 WeakPolarHBondContact O-CG2 3.36Å; I146-V150 PolarHBondContact O-N 2.96Å
147	L	84.7	Confident	85.2	Confident	0 Å²	0	59 Å²	59	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-56.8	-45.4	175.8	-77.9	164.8	0	0	0	111.8	M106 L110 T143 R149 F151 G152 L153 L155 L167	M106-L147 HydrophobicContact CB-CG 4.48Å; M106-L147 HydrophobicContact CG-CD2 3.66Å; M106-L147 HydrophobicContact CG-CG 3.94Å; L110-L147 HydrophobicContact CD1-CD2 4.1Å; L110-L147 HydrophobicContact CD2-CD2 3.77Å; L110-L147 HydrophobicContact CG-CD2 3.77Å; T143-L147 HydrophobicContact CG2-CD1 3.76Å; T143-L147 HydrophobicContact CG2-CG 4.24Å; T143-L147 WeakPolarHBondContact O-CB 3.25Å; T143-L147 WeakPolarHBondContact O-CG 3.3Å; T143-L147 PolarHBondContact O-N 2.87Å; L147-R149 VanDerWaalsContact C-N 3.31Å; L147-R149 PolarHBondContact O-N 2.88Å; L147-F151 HydrophobicContact CD2-CD2 4.32Å; L147-F151 CarbonylContact O-C 3.59Å; L147-F151 WeakPolarHBondContact O-CA 3.4Å; L147-F151 WeakPolarHBondContact O-CB 3.36Å; L147-F151 PolarHBondContact O-N 2.83Å; L147-G152 PolarHBondContact O-N 3.15Å; L147-L153 CarbonylContact C-O 3.46Å; L147-L153 VanDerWaalsContact CB-O 3.28Å; L147-L153 WeakPolarHBondContact CB-O 3.5Å; L147-L153 PolarHBondContact O-N 2.89Å; L147-L155 HydrophobicContact CD1-CB 3.88Å; L147-L167 HydrophobicContact CD1-CD2 3.74Å; L147-L167 HydrophobicContact CD2-CD2 4.27Å
148	A	81.6	Confident	84.9	Confident	30 Å²	30	53.3 Å²	53.3	25%	0.248	25%	0.254	C	S	.	.	H	α-helix	trans	-64	-38.7	178.6	0	0	0	0	0	111.5	S144 I146 G152 L153	S144-A148 WeakPolarHBondContact O-CB 3.46Å; S144-A148 PolarHBondContact O-N 3.26Å; I146-A148 VanDerWaalsContact C-N 3.33Å; I146-A148 PolarHBondContact O-N 2.92Å; A148-G152 WeakPolarHBondContact O-CA 3.37Å; A148-G152 PolarHBondContact O-N 3.14Å; A148-L153 VanDerWaalsContact CA-O 3.25Å; A148-L153 WeakPolarHBondContact CA-O 3.44Å; A148-L153 PolarHBondContact N-O 3.28Å
149	R	73.9	Confident	84.5	Confident	100 Å²	100	53 Å²	53	38%	0.377	25%	0.252	S	S	.	.	H	α-helix	trans	-74.6	-45.6	-178.8	-72.3	170.7	-172.8	-171.7	-2	113.5	L145 I146 L147	L145-R149 WeakPolarHBondContact O-CB 3.43Å; L145-R149 WeakPolarHBondContact O-CD 3.35Å; L145-R149 WeakPolarHBondContact O-CG 3.04Å; L145-R149 PolarHBondContact O-N 3.22Å; I146-R149 PolarHBondContact O-N 3.21Å; I146-R149 VanDerWaalsContact O-N 3.15Å; L147-R149 VanDerWaalsContact C-N 3.31Å; L147-R149 PolarHBondContact O-N 2.88Å
150	V	71.7	Confident	84.2	Confident	11 Å²	11	58.9 Å²	58.9	7%	0.067	28%	0.282	C	S	.	.	H	α-helix	trans	-88.8	-37.1	-170.9	-177.7	0	0	0	0	111.2	I146 M193 F278 V282	I146-V150 HydrophobicContact CG2-CG2 3.81Å; I146-V150 WeakPolarHBondContact O-CB 3.47Å; I146-V150 WeakPolarHBondContact O-CG2 3.36Å; I146-V150 PolarHBondContact O-N 2.96Å; V150-M193 HydrophobicContact CG1-CE 4.21Å; V150-F278 HydrophobicContact CG1-CE2 3.88Å; V150-F278 HydrophobicContact CG1-CZ 4.02Å; V150-V282 HydrophobicContact CB-CG2 4.49Å; V150-V282 HydrophobicContact CG1-CG2 4.11Å; V150-V282 HydrophobicContact CG2-CG2 4.19Å
151	F	74	Confident	83.9	Confident	23 Å²	23	66.6 Å²	66.6	10%	0.101	32%	0.317	C	S	.	.	H	α-helix	trans	-117.9	-9.5	-171.2	-65.9	-82.5	0	0	0	113.9	M106 W107 L110 L147 L153	M106-F151 HydrophobicContact CE-CE2 4.14Å; M106-F151 HydrophobicContact CG-CE2 4.28Å; M106-F151 HydrophobicContact SD-CD2 4.17Å; M106-F151 HydrophobicContact SD-CE2 3.72Å; W107-F151 AromaticContact CH2-CZ 3.9Å; W107-F151 HydrophobicContact CH2-CZ 3.9Å; W107-F151 HydrophobicContact CZ3-CE2 4.42Å; W107-F151 AromaticContact CZ3-CZ 3.73Å; W107-F151 HydrophobicContact CZ3-CZ 3.73Å; L110-F151 HydrophobicContact CD1-CD1 4.29Å; L110-F151 HydrophobicContact CD1-CD2 3.76Å; L110-F151 HydrophobicContact CD1-CE1 3.96Å; L110-F151 HydrophobicContact CD1-CE2 3.4Å; L110-F151 VanDerWaalsContact CD1-CE2 3.4Å; L110-F151 HydrophobicContact CD1-CG 4.2Å; L110-F151 HydrophobicContact CD1-CZ 3.52Å; L110-F151 HydrophobicContact CD2-CD1 4.2Å; L110-F151 HydrophobicContact CD2-CD2 4.35Å; L110-F151 HydrophobicContact CD2-CG 4.09Å; L147-F151 HydrophobicContact CD2-CD2 4.32Å; L147-F151 CarbonylContact O-C 3.59Å; L147-F151 WeakPolarHBondContact O-CA 3.4Å; L147-F151 WeakPolarHBondContact O-CB 3.36Å; L147-F151 PolarHBondContact O-N 2.83Å; F151-L153 HydrophobicContact CB-CB 4.38Å; F151-L153 HydrophobicContact CB-CD1 3.97Å; F151-L153 HydrophobicContact CB-CG 3.98Å; F151-L153 PolarHBondContact O-N 3.41Å
152	G	73.7	Confident	83.4	Confident	6 Å²	6	60 Å²	60	6%	0.062	30%	0.3	C	S	.	.	S	Bend	trans	64.9	30.8	-173.6	0	0	0	0	0	112.6	L147 A148 A170	L147-G152 PolarHBondContact O-N 3.15Å; A148-G152 WeakPolarHBondContact O-CA 3.37Å; A148-G152 PolarHBondContact O-N 3.14Å; G152-A170 VanDerWaalsContact O-CB 3.22Å; G152-A170 WeakPolarHBondContact O-CB 3.4Å; G152-A170 PolarHBondContact O-N 3.42Å
153	L	82.6	Confident	83.3	Confident	35 Å²	35	58.9 Å²	58.9	18%	0.183	30%	0.3	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.1	146.5	-177.6	-60.2	176.2	0	0	0	111.5	L110 L147 A148 F151 L167 V168	L110-L153 HydrophobicContact CD2-CD1 3.72Å; L147-L153 CarbonylContact C-O 3.46Å; L147-L153 VanDerWaalsContact CB-O 3.28Å; L147-L153 WeakPolarHBondContact CB-O 3.5Å; L147-L153 PolarHBondContact O-N 2.89Å; A148-L153 VanDerWaalsContact CA-O 3.25Å; A148-L153 WeakPolarHBondContact CA-O 3.44Å; A148-L153 PolarHBondContact N-O 3.28Å; F151-L153 HydrophobicContact CB-CB 4.38Å; F151-L153 HydrophobicContact CB-CD1 3.97Å; F151-L153 HydrophobicContact CB-CG 3.98Å; F151-L153 PolarHBondContact O-N 3.41Å; L153-L167 HydrophobicContact CB-CD2 4.25Å; L153-L167 HydrophobicContact CD1-CD1 3.95Å; L153-V168 CarbonylContact C-O 3.15Å
154	H	84.1	Confident	83.1	Confident	65 Å²	65	61 Å²	61	30%	0.301	31%	0.31	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-111.4	128.5	172	-83.7	-58.9	0	0	0	111	R156 L167 V168 A170	H154-R156 HydrophobicContact CB-CG 4.28Å; H154-R156 PolarHBondContact O-N 3.18Å; H154-L167 WeakPolarHBondContact O-CA 3.36Å; H154-V168 PolarHBondContact N-O 3.42Å; H154-V168 PolarHBondContact O-N 2.94Å; H154-A170 WeakPolarHBondContact CD2-CB 3.19Å
155	L	88.8	Confident	83.1	Confident	17 Å²	17	61.1 Å²	61.1	9%	0.089	31%	0.307	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-79.2	110.5	166.5	-177.6	58.6	0	0	0	109.1	V109 L140 L147 F165 L167	V109-L155 HydrophobicContact CG1-CD1 3.73Å; V109-L155 HydrophobicContact CG2-CD1 4.32Å; V109-L155 HydrophobicContact CG2-CD2 4.27Å; L140-L155 HydrophobicContact CD2-CD2 3.71Å; L147-L155 HydrophobicContact CD1-CB 3.88Å; L155-F165 HydrophobicContact CD1-CB 3.79Å; L155-F165 HydrophobicContact CD1-CD1 3.82Å; L155-F165 HydrophobicContact CD1-CG 4.2Å; L155-F165 HydrophobicContact CD2-CD1 4.42Å; L155-F165 HydrophobicContact CG-CD1 3.79Å; L155-F165 HydrophobicContact CG-CE1 4.45Å; L155-L167 HydrophobicContact CB-CD2 4.26Å; L155-L167 HydrophobicContact CD1-CD2 4.32Å
156	R	87	Confident	83.1	Confident	149 Å²	149	58.6 Å²	58.6	56%	0.562	30%	0.298	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-116.5	146.1	-179.9	-69.5	-165.5	173	-168.1	0.4	111.5	H154 F165 A166 V168	H154-R156 HydrophobicContact CB-CG 4.28Å; H154-R156 PolarHBondContact O-N 3.18Å; R156-F165 CarbonylContact O-C 3.24Å; R156-F165 VanDerWaalsContact O-CA 3.22Å; R156-F165 WeakPolarHBondContact O-CA 3.23Å; R156-F165 WeakPolarHBondContact O-CD1 3.4Å; R156-A166 PolarHBondContact N-O 3.5Å; R156-A166 PolarHBondContact O-N 3.04Å; R156-V168 HydrophobicContact CB-CG2 4.33Å; R156-V168 HydrophobicContact CG-CG2 4.37Å
157	L	87.7	Confident	83.2	Confident	76 Å²	76	58.5 Å²	58.5	40%	0.398	30%	0.298	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-81	117.6	168.3	-178.7	73.5	0	0	0	107.9	L160 E164 F165	L157-L160 HydrophobicContact CD2-CD1 3.98Å; L157-E164 CarbonylContact C-O 3.31Å; L157-E164 WeakPolarHBondContact CD1-O 3.34Å; L157-F165 HydrophobicContact CB-CD1 4.39Å; L157-F165 HydrophobicContact CB-CE1 4.01Å; L157-F165 HydrophobicContact CB-CZ 4.16Å; L157-F165 HydrophobicContact CD1-CD2 3.94Å; L157-F165 HydrophobicContact CD1-CE1 4.36Å; L157-F165 HydrophobicContact CD1-CE2 3.52Å; L157-F165 HydrophobicContact CD1-CG 4.5Å; L157-F165 HydrophobicContact CD1-CZ 3.78Å
158	T	85.1	Confident	83	Confident	99 Å²	99	61.4 Å²	61.4	61%	0.607	32%	0.315	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-87.5	-38.5	-177.7	-52.7	0	0	0	0	111.4	E164 A166	T158-E164 PolarHBondContact N-O 2.79Å; T158-A166 WeakPolarHBondContact OG1-CB 3.29Å
159	S	83.7	Confident	82.5	Confident	34 Å²	34	63.5 Å²	63.5	24%	0.238	32%	0.319	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-139.9	125.3	-178.7	165.6	0	0	0	0	110.2	H161 T162 M163 E164	S159-H161 VanDerWaalsContact C-N 3.33Å; S159-H161 PolarHBondContact OG-N 2.83Å; S159-T162 WeakPolarHBondContact CB-OG1 3.44Å; S159-T162 PolarHBondContact OG-N 3.3Å; S159-T162 PolarHBondContact OG-OG1 3.32Å; S159-M163 VanDerWaalsContact O-CA 3.24Å; S159-M163 WeakPolarHBondContact O-CA 3.26Å; S159-M163 PolarHBondContact O-N 3Å; S159-E164 PolarHBondContact O-N 3.02Å; S159-E164 VanDerWaalsContact O-N 3.15Å
160	L	84.5	Confident	82.1	Confident	123 Å²	123	60.5 Å²	60.5	64%	0.644	32%	0.315	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.2	-29.4	175.3	-174	64.6	0	0	0	111.6	L157 M163	L157-L160 HydrophobicContact CD2-CD1 3.98Å; L160-M163 HydrophobicContact CD1-CE 3.67Å; L160-M163 HydrophobicContact CD1-SD 4.08Å; L160-M163 HydrophobicContact CG-CE 4.34Å; L160-M163 VanDerWaalsContact O-CE 3.32Å; L160-M163 WeakPolarHBondContact O-CE 3.49Å
161	H	84.5	Confident	81.4	Confident	190 Å²	190	63.2 Å²	63.2	88%	0.88	33%	0.329	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.9	-44.6	-178.2	-115.3	-67.1	0	0	0	112	S159	S159-H161 VanDerWaalsContact C-N 3.33Å; S159-H161 PolarHBondContact OG-N 2.83Å
162	T	82.4	Confident	80.4	Confident	68 Å²	68	68.7 Å²	68.7	42%	0.417	36%	0.355	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.8	-7.9	178.9	52.4	0	0	0	0	112.4	S159 E164	S159-T162 WeakPolarHBondContact CB-OG1 3.44Å; S159-T162 PolarHBondContact OG-N 3.3Å; S159-T162 PolarHBondContact OG-OG1 3.32Å; T162-E164 VanDerWaalsContact CB-CD 3.45Å; T162-E164 PolarHBondContact O-N 3.32Å; T162-E164 VanDerWaalsContact OG1-CG 3.28Å; T162-E164 WeakPolarHBondContact OG1-CG 3.41Å; T162-E164 PolarHBondContact OG1-OE2 3.47Å
163	M	88	Confident	79.3	Confident	77 Å²	77	72.6 Å²	72.6	38%	0.379	38%	0.379	S	S	.	.	T	Hydrogen-bonded Turn	trans	52.4	44.4	-174.6	-64.9	-74	177.8	0	0	112.1	F121 S159 L160	F121-M163 HydrophobicContact CB-CB 3.81Å; F121-M163 VanDerWaalsContact CB-O 3.28Å; F121-M163 WeakPolarHBondContact CB-O 3.19Å; F121-M163 PolarHBondContact N-O 3.48Å; S159-M163 VanDerWaalsContact O-CA 3.24Å; S159-M163 WeakPolarHBondContact O-CA 3.26Å; S159-M163 PolarHBondContact O-N 3Å; L160-M163 HydrophobicContact CD1-CE 3.67Å; L160-M163 HydrophobicContact CD1-SD 4.08Å; L160-M163 HydrophobicContact CG-CE 4.34Å; L160-M163 VanDerWaalsContact O-CE 3.32Å; L160-M163 WeakPolarHBondContact O-CE 3.49Å
164	E	88.7	Confident	77.9	Confident	45 Å²	45	77 Å²	77	21%	0.21	40%	0.399	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-94.4	134.3	-174.6	-84	170.5	173.8	0	0	112.1	I118 W120 L157 T158 S159 T162	I118-E164 HydrophobicContact CG2-CG 3.69Å; W120-E164 VanDerWaalsContact CD1-CG 3.5Å; W120-E164 PolarHBondContact NE1-OE1 2.91Å; L157-E164 CarbonylContact C-O 3.31Å; L157-E164 WeakPolarHBondContact CD1-O 3.34Å; T158-E164 PolarHBondContact N-O 2.79Å; S159-E164 PolarHBondContact O-N 3.02Å; S159-E164 VanDerWaalsContact O-N 3.15Å; T162-E164 VanDerWaalsContact CB-CD 3.45Å; T162-E164 PolarHBondContact O-N 3.32Å; T162-E164 VanDerWaalsContact OG1-CG 3.28Å; T162-E164 WeakPolarHBondContact OG1-CG 3.41Å; T162-E164 PolarHBondContact OG1-OE2 3.47Å
165	F	88	Confident	76.2	Confident	29 Å²	29	79.2 Å²	79.2	13%	0.127	41%	0.409	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-109.8	149.1	176	-76.1	-97.3	0	0	0	111.7	I119 F121 M124 L155 R156 L157	I119-F165 HydrophobicContact CB-CB 4.19Å; I119-F165 WeakPolarHBondContact CB-O 3.43Å; I119-F165 HydrophobicContact CG2-CB 4.18Å; I119-F165 PolarHBondContact O-N 3.2Å; F121-F165 HydrophobicContact CB-CD2 4.24Å; F121-F165 HydrophobicContact CB-CE2 3.89Å; F121-F165 AromaticContact CD2-CE2 3.66Å; F121-F165 HydrophobicContact CD2-CE2 3.66Å; F121-F165 HydrophobicContact CD2-CZ 4.2Å; F121-F165 HydrophobicContact CG-CE2 4.21Å; M124-F165 HydrophobicContact CE-CE2 4.43Å; L155-F165 HydrophobicContact CD1-CB 3.79Å; L155-F165 HydrophobicContact CD1-CD1 3.82Å; L155-F165 HydrophobicContact CD1-CG 4.2Å; L155-F165 HydrophobicContact CD2-CD1 4.42Å; L155-F165 HydrophobicContact CG-CD1 3.79Å; L155-F165 HydrophobicContact CG-CE1 4.45Å; R156-F165 CarbonylContact O-C 3.24Å; R156-F165 VanDerWaalsContact O-CA 3.22Å; R156-F165 WeakPolarHBondContact O-CA 3.23Å; R156-F165 WeakPolarHBondContact O-CD1 3.4Å; L157-F165 HydrophobicContact CB-CD1 4.39Å; L157-F165 HydrophobicContact CB-CE1 4.01Å; L157-F165 HydrophobicContact CB-CZ 4.16Å; L157-F165 HydrophobicContact CD1-CD2 3.94Å; L157-F165 HydrophobicContact CD1-CE1 4.36Å; L157-F165 HydrophobicContact CD1-CE2 3.52Å; L157-F165 HydrophobicContact CD1-CG 4.5Å; L157-F165 HydrophobicContact CD1-CZ 3.78Å
166	A	86.4	Confident	74.2	Confident	30 Å²	30	79.6 Å²	79.6	25%	0.248	41%	0.411	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-138	152	172.1	0	0	0	0	0	111	R156 T158	R156-A166 PolarHBondContact N-O 3.5Å; R156-A166 PolarHBondContact O-N 3.04Å; T158-A166 WeakPolarHBondContact OG1-CB 3.29Å
167	L	86.2	Confident	72.3	Confident	21 Å²	21	78.6 Å²	78.6	11%	0.11	42%	0.417	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-85.4	125.8	167.5	-72.2	179	0	0	0	109.5	V109 L110 D113 L147 L153 H154 L155	V109-L167 HydrophobicContact CG1-CD1 3.74Å; V109-L167 HydrophobicContact CG1-CD2 3.59Å; V109-L167 HydrophobicContact CG1-CG 3.53Å; L110-L167 HydrophobicContact CD2-CD1 3.87Å; L110-L167 HydrophobicContact CG-CD1 4.46Å; D113-L167 HydrophobicContact CB-CD1 3.79Å; D113-L167 HydrophobicContact CB-CG 4.35Å; L147-L167 HydrophobicContact CD1-CD2 3.74Å; L147-L167 HydrophobicContact CD2-CD2 4.27Å; L153-L167 HydrophobicContact CB-CD2 4.25Å; L153-L167 HydrophobicContact CD1-CD1 3.95Å; H154-L167 WeakPolarHBondContact O-CA 3.36Å; L155-L167 HydrophobicContact CB-CD2 4.26Å; L155-L167 HydrophobicContact CD1-CD2 4.32Å
168	V	80.6	Confident	70.4	Confident	62 Å²	62	83.1 Å²	83.1	38%	0.376	43%	0.429	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.9	140.7	175.7	-174.5	0	0	0	0	108.2	L153 H154 R156 A170	L153-V168 CarbonylContact C-O 3.15Å; H154-V168 PolarHBondContact N-O 3.42Å; H154-V168 PolarHBondContact O-N 2.94Å; R156-V168 HydrophobicContact CB-CG2 4.33Å; R156-V168 HydrophobicContact CG-CG2 4.37Å; V168-A170 PolarHBondContact O-N 3.17Å
169	K	70.6	Confident	68.6	Low	74 Å²	74	78.6 Å²	78.6	32%	0.322	40%	0.401	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-60.7	131.6	175.3	-166.8	179.9	174.6	178.8	0	110	L171 E172 P173 L176	K169-L171 VanDerWaalsContact CD-O 3.27Å; K169-L171 WeakPolarHBondContact CD-O 3.48Å; K169-L171 WeakPolarHBondContact CE-O 3.32Å; K169-L171 WeakPolarHBondContact CG-O 3.41Å; K169-E172 WeakPolarHBondContact CE-O 3.44Å; K169-E172 PolarHBondContact NZ-O 2.88Å; K169-P173 PolarHBondContact NZ-O 3.05Å; K169-L176 HydrophobicContact CD-CD2 3.84Å; K169-L176 HydrophobicContact CG-CD2 4.39Å
170	A	65.5	Low	66.9	Low	36 Å²	36	79.6 Å²	79.6	30%	0.298	41%	0.411	S	S	.	.			trans	-85.6	-23.8	179.8	0	0	0	0	0	113.3	G152 H154 V168	G152-A170 VanDerWaalsContact O-CB 3.22Å; G152-A170 WeakPolarHBondContact O-CB 3.4Å; G152-A170 PolarHBondContact O-N 3.42Å; H154-A170 WeakPolarHBondContact CD2-CB 3.19Å; V168-A170 PolarHBondContact O-N 3.17Å
171	L	57.1	Low	65.3	Low	68 Å²	68	75.1 Å²	75.1	36%	0.356	39%	0.388	S	S	.	.	S	Bend	trans	-119.3	163.9	-168.4	-59.1	171.4	0	0	0	111.8	K169 E175	K169-L171 VanDerWaalsContact CD-O 3.27Å; K169-L171 WeakPolarHBondContact CD-O 3.48Å; K169-L171 WeakPolarHBondContact CE-O 3.32Å; K169-L171 WeakPolarHBondContact CG-O 3.41Å; L171-E175 HydrophobicContact CB-CB 4.48Å; L171-E175 WeakPolarHBondContact CD2-OE2 3.41Å
172	E	53.5	Low	63.5	Low	139 Å²	139	68.8 Å²	68.8	65%	0.65	37%	0.365	S	S	*	.			trans	-60.4	151.2	174.3	-74.9	-63	121.5	0	0	111.7	K169 E174 E175	K169-E172 WeakPolarHBondContact CE-O 3.44Å; K169-E172 PolarHBondContact NZ-O 2.88Å; E172-E174 PolarHBondContact O-N 2.92Å; E172-E174 VanDerWaalsContact O-N 3.17Å; E172-E175 PolarHBondContact O-N 3.37Å
173	P	51	Low	61.9	Low	88 Å²	88	69.6 Å²	69.6	57%	0.571	37%	0.367	S	S	*	.	H	α-helix	trans	-34.5	-52.9	168.9	-33.9	39.7	0	0	0	113.7	K169 E175 L176 D177	K169-P173 PolarHBondContact NZ-O 3.05Å; P173-E175 PolarHBondContact O-N 3.15Å; P173-L176 PolarHBondContact O-N 2.99Å; P173-D177 PolarHBondContact O-N 2.83Å
174	E	52	Low	60.2	Low	126 Å²	126	75.2 Å²	75.2	59%	0.589	38%	0.384	S	S	*	.	H	α-helix	trans	-66	-39.2	-168	-152	-172.4	155.4	0	0	114.2	E172 L176 D177 R178	E172-E174 PolarHBondContact O-N 2.92Å; E172-E174 VanDerWaalsContact O-N 3.17Å; E174-L176 VanDerWaalsContact C-N 3.35Å; E174-L176 PolarHBondContact O-N 2.79Å; E174-D177 PolarHBondContact O-N 3.25Å; E174-R178 PolarHBondContact O-N 2.87Å; E174-R178 VanDerWaalsContact O-N 3.14Å; E174-R178 IonicContact OE1-NH2 3.46Å; E174-R178 PolarHBondContact OE1-NH2 3.2Å
175	E	49.6	Very low	58.9	Low	112 Å²	112	77.4 Å²	77.4	52%	0.523	40%	0.395	S	S	.	.	H	α-helix	trans	-72.2	-29.8	-179.9	-66.7	-168.5	143.5	0	0	112.7	L171 E172 P173	L171-E175 HydrophobicContact CB-CB 4.48Å; L171-E175 WeakPolarHBondContact CD2-OE2 3.41Å; E172-E175 PolarHBondContact O-N 3.37Å; P173-E175 PolarHBondContact O-N 3.15Å
176	L	46.5	Very low	57.6	Low	26 Å²	26	76.3 Å²	76.3	14%	0.136	39%	0.391	C	S	.	.	H	α-helix	trans	-81	-29.2	172.7	-167.5	70.4	0	0	0	111.3	K169 P173 E174 V179 A180	K169-L176 HydrophobicContact CD-CD2 3.84Å; K169-L176 HydrophobicContact CG-CD2 4.39Å; P173-L176 PolarHBondContact O-N 2.99Å; E174-L176 VanDerWaalsContact C-N 3.35Å; E174-L176 PolarHBondContact O-N 2.79Å; L176-V179 CarbonylContact O-C 2.92Å; L176-V179 PolarHBondContact O-N 2.82Å; L176-A180 PolarHBondContact O-N 3.46Å
177	D	46.6	Very low	57.1	Low	128 Å²	128	77.3 Å²	77.3	68%	0.684	39%	0.391	S	S	*	.	H	α-helix	trans	-71	-37.4	-179.5	-148.6	40.4	0	0	0	111.1	P173 E174 V179	P173-D177 PolarHBondContact O-N 2.83Å; E174-D177 PolarHBondContact O-N 3.25Å; D177-V179 PolarHBondContact O-N 3.38Å; D177-V179 VanDerWaalsContact O-N 3.13Å
178	R	48.8	Very low	56.6	Low	171 Å²	171	77.4 Å²	77.4	65%	0.645	39%	0.393	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58	-27.2	171.1	-75.7	-179.4	-167.9	-100.2	-3.1	112.9	E174	E174-R178 PolarHBondContact O-N 2.87Å; E174-R178 VanDerWaalsContact O-N 3.14Å; E174-R178 IonicContact OE1-NH2 3.46Å; E174-R178 PolarHBondContact OE1-NH2 3.2Å
179	V	47.2	Very low	56.5	Low	3 Å²	3	74.7 Å²	74.7	2%	0.018	38%	0.377	C	S	.	.	T	Hydrogen-bonded Turn	trans	-127.1	84.8	174.6	-155.3	0	0	0	0	108	L176 D177 L181 Q274 E277 R281	L176-V179 CarbonylContact O-C 2.92Å; L176-V179 PolarHBondContact O-N 2.82Å; D177-V179 PolarHBondContact O-N 3.38Å; D177-V179 VanDerWaalsContact O-N 3.13Å; V179-L181 HydrophobicContact CB-CD1 4.36Å; V179-L181 HydrophobicContact CB-CG 4.04Å; V179-L181 HydrophobicContact CG1-CD1 3.87Å; V179-L181 HydrophobicContact CG1-CD2 3.78Å; V179-L181 HydrophobicContact CG1-CG 3.48Å; V179-L181 VanDerWaalsContact CG1-CG 3.48Å; V179-L181 WeakPolarHBondContact O-CB 3.24Å; V179-L181 WeakPolarHBondContact O-CG 3.07Å; V179-L181 PolarHBondContact O-N 3.07Å; V179-Q274 HydrophobicContact CG1-CB 4.41Å; V179-Q274 HydrophobicContact CG1-CG 4.38Å; V179-E277 WeakPolarHBondContact CG2-OE2 3.4Å; V179-R281 VanDerWaalsContact CG1-NH2 3.27Å
180	A	47.3	Very low	57.1	Low	55 Å²	55	71.2 Å²	71.2	46%	0.455	36%	0.362	S	S	.	.			trans	-52.2	29.8	174.3	0	0	0	0	0	116.1	L176 S182 N183	L176-A180 PolarHBondContact O-N 3.46Å; A180-S182 PolarHBondContact O-N 3.34Å; A180-S182 VanDerWaalsContact O-N 3.14Å; A180-N183 PolarHBondContact O-N 2.99Å; A180-N183 VanDerWaalsContact O-N 3.09Å
181	L	50.6	Low	58.2	Low	29 Å²	29	69.8 Å²	69.8	15%	0.152	35%	0.349	C	S	.	.	T	Hydrogen-bonded Turn	trans	-52.1	-16.4	156	-51.1	-174.5	0	0	0	112.7	V179 N183 L192 F278	V179-L181 HydrophobicContact CB-CD1 4.36Å; V179-L181 HydrophobicContact CB-CG 4.04Å; V179-L181 HydrophobicContact CG1-CD1 3.87Å; V179-L181 HydrophobicContact CG1-CD2 3.78Å; V179-L181 HydrophobicContact CG1-CG 3.48Å; V179-L181 VanDerWaalsContact CG1-CG 3.48Å; V179-L181 WeakPolarHBondContact O-CB 3.24Å; V179-L181 WeakPolarHBondContact O-CG 3.07Å; V179-L181 PolarHBondContact O-N 3.07Å; L181-N183 PolarHBondContact O-N 3.41Å; L181-L192 HydrophobicContact CD2-CD1 2.93Å; L181-L192 HydrophobicContact CD2-CG 4.39Å; L181-L192 HydrophobicContact CG-CD1 4.41Å; L181-F278 HydrophobicContact CD1-CD2 4.24Å
182	S	47.4	Very low	59.5	Low	58 Å²	58	66.9 Å²	66.9	41%	0.406	33%	0.334	S	S	.	.	T	Hydrogen-bonded Turn	trans	-68	-0.1	170.7	75.2	0	0	0	0	113.3	A180 R184	A180-S182 PolarHBondContact O-N 3.34Å; A180-S182 VanDerWaalsContact O-N 3.14Å; S182-R184 WeakPolarHBondContact O-CG 3.28Å; S182-R184 PolarHBondContact O-N 3.43Å
183	N	49.5	Very low	61	Low	85 Å²	85	61 Å²	61	46%	0.455	31%	0.307	S	S	.	.	S	Bend	trans	-60.6	97.4	156.6	-168	5.8	0	0	0	106.5	A180 L181 M185 T188	A180-N183 PolarHBondContact O-N 2.99Å; A180-N183 VanDerWaalsContact O-N 3.09Å; L181-N183 PolarHBondContact O-N 3.41Å; N183-M185 PolarHBondContact O-N 3.34Å; N183-T188 PolarHBondContact O-OG1 3.37Å; N183-T188 VanDerWaalsContact O-OG1 3.12Å
184	R	51.8	Low	62.9	Low	195 Å²	195	56.9 Å²	56.9	74%	0.736	28%	0.28	S	S	*	.			trans	-54.9	10.2	-163.4	-69.1	-168.2	172.4	-125.5	5.1	115.6	Q114 S182	Q114-R184 WeakPolarHBondContact CG-O 3.48Å; S182-R184 WeakPolarHBondContact O-CG 3.28Å; S182-R184 PolarHBondContact O-N 3.43Å
185	M	60.5	Low	64.7	Low	91 Å²	91	50.9 Å²	50.9	45%	0.448	25%	0.252	S	S	.	.			trans	-86.4	123.3	177.1	-50.9	-158.5	179.7	0	0	110.7	N183 M187 T188	N183-M185 PolarHBondContact O-N 3.34Å; M185-M187 HydrophobicContact CB-CB 4.1Å; M185-M187 PolarHBondContact O-N 3.28Å; M185-T188 WeakPolarHBondContact O-CA 3.29Å; M185-T188 WeakPolarHBondContact O-CB 3.26Å; M185-T188 PolarHBondContact O-N 3.06Å; M185-T188 PolarHBondContact O-OG1 3.03Å; M185-T188 VanDerWaalsContact O-OG1 3.12Å
186	P	62.1	Low	66.5	Low	6 Å²	6	45.6 Å²	45.6	4%	0.039	23%	0.228	C	C	.	.	H	α-helix	trans	-58.3	-25.4	165.8	27.8	-32.5	0	0	0	111	L110 V111 Q114 T188 G189 L190 F228	L110-P186 HydrophobicContact CB-CB 3.84Å; V111-P186 HydrophobicContact CB-CG 4.05Å; V111-P186 HydrophobicContact CG2-CB 3.62Å; V111-P186 HydrophobicContact CG2-CG 3.24Å; Q114-P186 HydrophobicContact CB-CG 4.39Å; P186-T188 VanDerWaalsContact C-N 3.28Å; P186-T188 PolarHBondContact O-N 3.15Å; P186-G189 PolarHBondContact O-N 2.97Å; P186-L190 PolarHBondContact O-N 2.95Å; P186-L190 VanDerWaalsContact O-N 3.08Å; P186-F228 HydrophobicContact CB-CE1 4.22Å; P186-F228 HydrophobicContact CB-CZ 4.22Å; P186-F228 HydrophobicContact CG-CE1 4.34Å
187	M	75	Confident	68.4	Low	50 Å²	50	46 Å²	46	25%	0.246	23%	0.23	C	C	.	.	H	α-helix	trans	-59.6	-36.1	169.5	-63.4	174.5	174.3	0	0	111.9	M185 G189 L190 L191 F228 L234 F239	M185-M187 HydrophobicContact CB-CB 4.1Å; M185-M187 PolarHBondContact O-N 3.28Å; M187-G189 VanDerWaalsContact C-N 3.32Å; M187-G189 PolarHBondContact O-N 3.34Å; M187-L190 PolarHBondContact O-N 2.97Å; M187-L191 WeakPolarHBondContact O-CB 3.45Å; M187-L191 PolarHBondContact O-N 3.13Å; M187-F228 HydrophobicContact CG-CE1 4.34Å; M187-L234 HydrophobicContact CE-CD1 3.97Å; M187-L234 HydrophobicContact CG-CD1 4.42Å; M187-L234 HydrophobicContact SD-CD1 4.24Å; M187-F239 HydrophobicContact CB-CE1 4.04Å; M187-F239 HydrophobicContact CB-CZ 4.09Å; M187-F239 WeakPolarHBondContact O-CZ 3.14Å
188	T	76.2	Confident	70.5	Confident	24 Å²	24	40 Å²	40	15%	0.147	20%	0.198	C	C	.	.	H	α-helix	trans	-60.8	-43	173.7	-48.1	0	0	0	0	110.7	N183 M185 P186 L191 L192	N183-T188 PolarHBondContact O-OG1 3.37Å; N183-T188 VanDerWaalsContact O-OG1 3.12Å; M185-T188 WeakPolarHBondContact O-CA 3.29Å; M185-T188 WeakPolarHBondContact O-CB 3.26Å; M185-T188 PolarHBondContact O-N 3.06Å; M185-T188 PolarHBondContact O-OG1 3.03Å; M185-T188 VanDerWaalsContact O-OG1 3.12Å; P186-T188 VanDerWaalsContact C-N 3.28Å; P186-T188 PolarHBondContact O-N 3.15Å; T188-L191 PolarHBondContact O-N 3.25Å; T188-L192 HydrophobicContact CG2-CD1 3.94Å; T188-L192 HydrophobicContact CG2-CG 4.49Å; T188-L192 WeakPolarHBondContact O-CB 3.45Å; T188-L192 WeakPolarHBondContact O-CG 3.07Å; T188-L192 PolarHBondContact O-N 3.24Å
189	G	77.8	Confident	72.3	Confident	5 Å²	5	32.8 Å²	32.8	5%	0.052	17%	0.17	C	C	.	.	H	α-helix	trans	-61.2	-47	176.1	0	0	0	0	0	113.2	P186 M187 M193	P186-G189 PolarHBondContact O-N 2.97Å; M187-G189 VanDerWaalsContact C-N 3.32Å; M187-G189 PolarHBondContact O-N 3.34Å; G189-M193 WeakPolarHBondContact O-CB 3.43Å; G189-M193 PolarHBondContact O-N 2.91Å
190	L	83.9	Confident	74	Confident	0 Å²	0	35.7 Å²	35.7	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-63.1	-45.9	175.8	178.6	54.7	0	0	0	111.3	W107 P186 M187 L192 M193 I194 L214 L219 V231 L234 I235 F239	W107-L190 HydrophobicContact CH2-CB 4.04Å; W107-L190 HydrophobicContact CZ3-CB 4.32Å; P186-L190 PolarHBondContact O-N 2.95Å; P186-L190 VanDerWaalsContact O-N 3.08Å; M187-L190 PolarHBondContact O-N 2.97Å; L190-L192 PolarHBondContact O-N 3.49Å; L190-M193 WeakPolarHBondContact O-CB 3.41Å; L190-M193 PolarHBondContact O-N 2.81Å; L190-I194 HydrophobicContact CD1-CD1 4.1Å; L190-I194 HydrophobicContact CD1-CG1 4.42Å; L190-I194 HydrophobicContact CG-CD1 4.07Å; L190-I194 WeakPolarHBondContact O-CG1 3.4Å; L190-I194 PolarHBondContact O-N 3.22Å; L190-I194 VanDerWaalsContact O-N 3.07Å; L190-L214 HydrophobicContact CD1-CD2 4.1Å; L190-L214 HydrophobicContact CD1-CG 4.28Å; L190-L219 HydrophobicContact CD1-CD1 3.31Å; L190-L219 HydrophobicContact CD2-CD1 4.13Å; L190-L219 HydrophobicContact CG-CD1 4.31Å; L190-V231 HydrophobicContact CD2-CG1 4.43Å; L190-L234 HydrophobicContact CD2-CD2 3.82Å; L190-I235 HydrophobicContact CD2-CD1 4.41Å; L190-F239 HydrophobicContact CD2-CE2 4.32Å; L190-F239 HydrophobicContact CG-CE2 4.16Å
191	L	87.7	Confident	75.8	Confident	6 Å²	6	39.9 Å²	39.9	3%	0.031	20%	0.196	C	C	.	.	H	α-helix	trans	-58.7	-49.5	178.5	172.9	61.8	0	0	0	111	M187 T188 M193 I194 L195 F239 Y244 L245	M187-L191 WeakPolarHBondContact O-CB 3.45Å; M187-L191 PolarHBondContact O-N 3.13Å; T188-L191 PolarHBondContact O-N 3.25Å; L191-M193 VanDerWaalsContact C-N 3.28Å; L191-M193 PolarHBondContact O-N 2.85Å; L191-I194 PolarHBondContact O-N 3.35Å; L191-I194 VanDerWaalsContact O-N 3.1Å; L191-L195 HydrophobicContact CD1-CD1 3.83Å; L191-L195 HydrophobicContact CD1-CD2 4.45Å; L191-L195 HydrophobicContact CD1-CG 3.89Å; L191-L195 HydrophobicContact CD2-CD1 4.34Å; L191-L195 HydrophobicContact CG-CD1 3.75Å; L191-L195 HydrophobicContact CG-CG 4.22Å; L191-L195 WeakPolarHBondContact O-CB 3.5Å; L191-L195 WeakPolarHBondContact O-CG 3.36Å; L191-L195 PolarHBondContact O-N 2.97Å; L191-F239 HydrophobicContact CB-CE1 4.34Å; L191-F239 HydrophobicContact CB-CE2 4.02Å; L191-F239 HydrophobicContact CB-CZ 3.91Å; L191-F239 HydrophobicContact CD1-CD2 4.11Å; L191-F239 HydrophobicContact CD1-CE2 4.42Å; L191-F239 HydrophobicContact CD1-CG 4.23Å; L191-Y244 HydrophobicContact CD1-CG 4.28Å; L191-Y244 HydrophobicContact CD2-CD1 3.53Å; L191-Y244 HydrophobicContact CD2-CD2 3.84Å; L191-Y244 HydrophobicContact CD2-CE1 3.94Å; L191-Y244 HydrophobicContact CD2-CE2 4.22Å; L191-Y244 HydrophobicContact CD2-CG 3.47Å; L191-Y244 VanDerWaalsContact CD2-CG 3.47Å; L191-L245 HydrophobicContact CD1-CD2 4.44Å; L191-L245 HydrophobicContact CD1-CG 4.21Å
192	L	85.2	Confident	77.2	Confident	7 Å²	7	40.3 Å²	40.3	4%	0.037	21%	0.208	C	C	.	.	H	α-helix	trans	-63.5	-35.6	178.7	-78.4	166.6	0	0	0	112.6	L181 T188 L190 I194 L195 S196 I270 I275	L181-L192 HydrophobicContact CD2-CD1 2.93Å; L181-L192 HydrophobicContact CD2-CG 4.39Å; L181-L192 HydrophobicContact CG-CD1 4.41Å; T188-L192 HydrophobicContact CG2-CD1 3.94Å; T188-L192 HydrophobicContact CG2-CG 4.49Å; T188-L192 WeakPolarHBondContact O-CB 3.45Å; T188-L192 WeakPolarHBondContact O-CG 3.07Å; T188-L192 PolarHBondContact O-N 3.24Å; L190-L192 PolarHBondContact O-N 3.49Å; L192-I194 VanDerWaalsContact C-N 3.31Å; L192-I194 PolarHBondContact O-N 3.03Å; L192-L195 PolarHBondContact O-N 3.49Å; L192-S196 WeakPolarHBondContact O-CB 3.36Å; L192-S196 PolarHBondContact O-N 2.9Å; L192-S196 PolarHBondContact O-OG 2.86Å; L192-I270 HydrophobicContact CD2-CD1 3.72Å; L192-I270 HydrophobicContact CD2-CG1 4.16Å; L192-I270 HydrophobicContact CD2-CG2 3.74Å; L192-I270 HydrophobicContact CG-CD1 4.45Å; L192-I275 HydrophobicContact CD2-CD1 3.81Å
193	M	85	Confident	78.9	Confident	17 Å²	17	48.8 Å²	48.8	8%	0.084	23%	0.231	C	C	.	.	H	α-helix	trans	-60.3	-44.3	173.2	-168.1	68.1	71.6	0	0	111.5	V150 G189 L190 L191 L197 L217 F278 V282	V150-M193 HydrophobicContact CG1-CE 4.21Å; G189-M193 WeakPolarHBondContact O-CB 3.43Å; G189-M193 PolarHBondContact O-N 2.91Å; L190-M193 WeakPolarHBondContact O-CB 3.41Å; L190-M193 PolarHBondContact O-N 2.81Å; L191-M193 VanDerWaalsContact C-N 3.28Å; L191-M193 PolarHBondContact O-N 2.85Å; M193-L197 WeakPolarHBondContact O-CB 3.35Å; M193-L197 PolarHBondContact O-N 3.41Å; M193-L217 HydrophobicContact CE-CD1 3.93Å; M193-L217 HydrophobicContact CE-CD2 4.36Å; M193-L217 HydrophobicContact CG-CD1 3.39Å; M193-L217 HydrophobicContact SD-CD1 3.83Å; M193-F278 HydrophobicContact CB-CE1 4.47Å; M193-F278 HydrophobicContact CB-CZ 4.49Å; M193-F278 HydrophobicContact CE-CE1 3.97Å; M193-F278 HydrophobicContact CE-CZ 3.64Å; M193-F278 HydrophobicContact SD-CE1 3.88Å; M193-F278 HydrophobicContact SD-CZ 4.16Å; M193-V282 HydrophobicContact CE-CG1 4.42Å; M193-V282 HydrophobicContact CE-CG2 4.24Å
194	I	90.1	Very high	80.8	Confident	0 Å²	0	45.3 Å²	45.3	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-67.7	-47.3	178.1	-62.6	162	0	0	0	110.5	L190 L191 L192 S196 L197 I198 V210 L214 I235 F239 L245	L190-I194 HydrophobicContact CD1-CD1 4.1Å; L190-I194 HydrophobicContact CD1-CG1 4.42Å; L190-I194 HydrophobicContact CG-CD1 4.07Å; L190-I194 WeakPolarHBondContact O-CG1 3.4Å; L190-I194 PolarHBondContact O-N 3.22Å; L190-I194 VanDerWaalsContact O-N 3.07Å; L191-I194 PolarHBondContact O-N 3.35Å; L191-I194 VanDerWaalsContact O-N 3.1Å; L192-I194 VanDerWaalsContact C-N 3.31Å; L192-I194 PolarHBondContact O-N 3.03Å; I194-S196 VanDerWaalsContact C-N 3.29Å; I194-S196 PolarHBondContact O-N 3.38Å; I194-L197 WeakPolarHBondContact O-CB 3.16Å; I194-L197 PolarHBondContact O-N 2.75Å; I194-L197 VanDerWaalsContact O-N 3.14Å; I194-I198 HydrophobicContact CG2-CD1 3.9Å; I194-I198 HydrophobicContact CG2-CG1 4.5Å; I194-I198 WeakPolarHBondContact O-CG1 3.48Å; I194-I198 PolarHBondContact O-N 2.9Å; I194-V210 HydrophobicContact CG1-CG1 4.22Å; I194-V210 HydrophobicContact CG2-CG1 4.05Å; I194-L214 HydrophobicContact CD1-CD2 4.42Å; I194-L214 HydrophobicContact CG1-CD1 3.97Å; I194-I235 HydrophobicContact CD1-CD1 3.49Å; I194-I235 VanDerWaalsContact CD1-CD1 3.49Å; I194-I235 HydrophobicContact CD1-CG1 3.68Å; I194-I235 HydrophobicContact CD1-CG2 4.08Å; I194-F239 HydrophobicContact CD1-CD2 4.26Å; I194-F239 HydrophobicContact CD1-CE2 4.09Å; I194-L245 HydrophobicContact CG2-CD1 3.95Å; I194-L245 HydrophobicContact CG2-CD2 4.01Å
195	L	90.7	Very high	82.8	Confident	0 Å²	0	36.1 Å²	36.1	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-60.6	-39.8	177.5	-70.3	175.1	0	0	0	111.7	L191 L192 I198 Y199 L245 W262 A266 I270 I275	L191-L195 HydrophobicContact CD1-CD1 3.83Å; L191-L195 HydrophobicContact CD1-CD2 4.45Å; L191-L195 HydrophobicContact CD1-CG 3.89Å; L191-L195 HydrophobicContact CD2-CD1 4.34Å; L191-L195 HydrophobicContact CG-CD1 3.75Å; L191-L195 HydrophobicContact CG-CG 4.22Å; L191-L195 WeakPolarHBondContact O-CB 3.5Å; L191-L195 WeakPolarHBondContact O-CG 3.36Å; L191-L195 PolarHBondContact O-N 2.97Å; L192-L195 PolarHBondContact O-N 3.49Å; L195-I198 PolarHBondContact O-N 3.14Å; L195-Y199 VanDerWaalsContact O-CB 3.32Å; L195-Y199 WeakPolarHBondContact O-CB 3.36Å; L195-Y199 PolarHBondContact O-N 3.17Å; L195-L245 HydrophobicContact CD2-CD2 3.67Å; L195-L245 HydrophobicContact CG-CD2 4.42Å; L195-W262 HydrophobicContact CB-CH2 4.41Å; L195-W262 HydrophobicContact CB-CZ2 3.73Å; L195-W262 HydrophobicContact CD2-CD2 3.77Å; L195-W262 HydrophobicContact CD2-CE3 4.36Å; L195-W262 HydrophobicContact CD2-CG 3.82Å; L195-W262 HydrophobicContact CD2-CZ2 4.4Å; L195-W262 PolarHBondContact O-NE1 2.95Å; L195-A266 HydrophobicContact CD1-CB 3.8Å; L195-A266 HydrophobicContact CD2-CB 3.78Å; L195-A266 HydrophobicContact CG-CB 4.48Å; L195-I270 HydrophobicContact CD1-CD1 3.22Å; L195-I275 HydrophobicContact CB-CD1 4.02Å
196	S	86.1	Confident	84.2	Confident	1 Å²	1	37.3 Å²	37.3	1%	0.007	18%	0.18	C	C	.	.	H	α-helix	trans	-63.8	-41.7	175.1	-60.2	0	0	0	0	111.6	L192 I194 Y199 V200 F278	L192-S196 WeakPolarHBondContact O-CB 3.36Å; L192-S196 PolarHBondContact O-N 2.9Å; L192-S196 PolarHBondContact O-OG 2.86Å; I194-S196 VanDerWaalsContact C-N 3.29Å; I194-S196 PolarHBondContact O-N 3.38Å; S196-Y199 WeakPolarHBondContact O-CB 3.44Å; S196-Y199 PolarHBondContact O-N 3.33Å; S196-V200 VanDerWaalsContact O-CG2 3.27Å; S196-V200 WeakPolarHBondContact O-CG2 3.29Å; S196-V200 PolarHBondContact O-N 3.15Å; S196-F278 VanDerWaalsContact OG-CD1 3.28Å; S196-F278 WeakPolarHBondContact OG-CD1 3Å
197	L	87.6	Confident	85.7	Confident	36 Å²	36	38.5 Å²	38.5	19%	0.188	19%	0.185	C	C	.	.	H	α-helix	trans	-64	-43.7	175.5	177	60.4	0	0	0	111.9	M193 I194 Y199 V200 K201 V210 V213	M193-L197 WeakPolarHBondContact O-CB 3.35Å; M193-L197 PolarHBondContact O-N 3.41Å; I194-L197 WeakPolarHBondContact O-CB 3.16Å; I194-L197 PolarHBondContact O-N 2.75Å; I194-L197 VanDerWaalsContact O-N 3.14Å; L197-Y199 VanDerWaalsContact C-N 3.32Å; L197-V200 PolarHBondContact O-N 2.97Å; L197-K201 PolarHBondContact O-N 2.84Å; L197-V210 HydrophobicContact CD2-CB 4.26Å; L197-V210 HydrophobicContact CD2-CG2 4.02Å; L197-V213 HydrophobicContact CD1-CG2 3.98Å; L197-V213 HydrophobicContact CD2-CB 3.81Å; L197-V213 HydrophobicContact CD2-CG1 4.26Å; L197-V213 HydrophobicContact CD2-CG2 3.75Å
198	I	90.7	Very high	86.4	Confident	1 Å²	1	39.9 Å²	39.9	1%	0.005	20%	0.2	C	C	.	.	H	α-helix	trans	-62.4	-44	175.5	-62	161.2	0	0	0	109.9	I194 L195 V200 K201 G202 A205 L245 F260 W262	I194-I198 HydrophobicContact CG2-CD1 3.9Å; I194-I198 HydrophobicContact CG2-CG1 4.5Å; I194-I198 WeakPolarHBondContact O-CG1 3.48Å; I194-I198 PolarHBondContact O-N 2.9Å; L195-I198 PolarHBondContact O-N 3.14Å; I198-V200 PolarHBondContact O-N 2.82Å; I198-K201 CarbonylContact O-C 3.59Å; I198-K201 PolarHBondContact O-N 2.93Å; I198-K201 VanDerWaalsContact O-N 3.17Å; I198-G202 PolarHBondContact O-N 3.41Å; I198-A205 HydrophobicContact CB-CB 4.38Å; I198-A205 HydrophobicContact CG1-CB 3.77Å; I198-L245 HydrophobicContact CD1-CD2 3.67Å; I198-F260 HydrophobicContact CD1-CB 3.75Å; I198-F260 HydrophobicContact CG1-CB 4.3Å; I198-W262 VanDerWaalsContact CG2-CD1 3.49Å
199	Y	86.6	Confident	86.9	Confident	19 Å²	19	40.6 Å²	40.6	8%	0.075	21%	0.208	C	C	.	.	H	α-helix	trans	-58.4	-49.1	176.5	179.9	-108.2	0	0	0	110.8	L195 S196 L197 K201 G202 K272 I275 L279 R293	L195-Y199 VanDerWaalsContact O-CB 3.32Å; L195-Y199 WeakPolarHBondContact O-CB 3.36Å; L195-Y199 PolarHBondContact O-N 3.17Å; S196-Y199 WeakPolarHBondContact O-CB 3.44Å; S196-Y199 PolarHBondContact O-N 3.33Å; L197-Y199 VanDerWaalsContact C-N 3.32Å; Y199-K201 VanDerWaalsContact C-N 3.29Å; Y199-K201 PolarHBondContact O-N 2.89Å; Y199-G202 WeakPolarHBondContact O-CA 3.36Å; Y199-G202 PolarHBondContact O-N 2.77Å; Y199-K272 HydrophobicContact CD2-CG 4.43Å; Y199-K272 HydrophobicContact CE2-CB 4.22Å; Y199-K272 HydrophobicContact CE2-CD 3.72Å; Y199-K272 HydrophobicContact CE2-CG 3.76Å; Y199-I275 HydrophobicContact CD1-CB 4.49Å; Y199-I275 HydrophobicContact CD1-CG2 3.51Å; Y199-I275 HydrophobicContact CE1-CG2 4.26Å; Y199-I275 HydrophobicContact CG-CG2 3.87Å; Y199-L279 HydrophobicContact CD1-CD1 4.36Å; Y199-R293 HydrophobicContact CE1-CB 4.4Å; Y199-R293 PolarHBondContact O-NH1 3.3Å; Y199-R293 PolarHBondContact O-NH2 3.14Å
200	V	83.1	Confident	87.5	Confident	65 Å²	65	40.3 Å²	40.3	39%	0.394	21%	0.205	S	C	.	.	H	α-helix	trans	-56.3	-44.3	176.4	171.2	0	0	0	0	110.9	S196 L197 I198 G202 L279 R293	S196-V200 VanDerWaalsContact O-CG2 3.27Å; S196-V200 WeakPolarHBondContact O-CG2 3.29Å; S196-V200 PolarHBondContact O-N 3.15Å; L197-V200 PolarHBondContact O-N 2.97Å; I198-V200 PolarHBondContact O-N 2.82Å; V200-G202 VanDerWaalsContact C-N 3.27Å; V200-G202 PolarHBondContact O-N 3.15Å; V200-L279 HydrophobicContact CG2-CD1 3.69Å; V200-L279 HydrophobicContact CG2-CD2 4.12Å; V200-R293 PolarHBondContact O-NH2 3.4Å
201	K	83.5	Confident	87.8	Confident	142 Å²	142	41.2 Å²	41.2	62%	0.617	21%	0.208	S	C	*	.	H	α-helix	trans	-67.5	-26.2	177.9	-165.4	62.8	173.8	177.1	0	113.2	L197 I198 Y199 G204 A205	L197-K201 PolarHBondContact O-N 2.84Å; I198-K201 CarbonylContact O-C 3.59Å; I198-K201 PolarHBondContact O-N 2.93Å; I198-K201 VanDerWaalsContact O-N 3.17Å; Y199-K201 VanDerWaalsContact C-N 3.29Å; Y199-K201 PolarHBondContact O-N 2.89Å; K201-G204 WeakPolarHBondContact CG-O 3.17Å; K201-A205 HydrophobicContact CB-CB 4.28Å; K201-A205 HydrophobicContact CG-CB 4.4Å
202	G	80.7	Confident	87.8	Confident	38 Å²	38	44.8 Å²	44.8	39%	0.392	23%	0.228	S	C	.	.	S	Bend	trans	106.9	-103.1	175.9	0	0	0	0	0	111.6	I198 Y199 V200	I198-G202 PolarHBondContact O-N 3.41Å; Y199-G202 WeakPolarHBondContact O-CA 3.36Å; Y199-G202 PolarHBondContact O-N 2.77Å; V200-G202 VanDerWaalsContact C-N 3.27Å; V200-G202 PolarHBondContact O-N 3.15Å
203	R	83.8	Confident	87.6	Confident	237 Å²	237	46.6 Å²	46.6	89%	0.894	24%	0.239	S	C	*	.	S	Bend	trans	-71.5	-36.3	-171.7	-158.8	-176.3	-169.4	-175.5	4	113.4	F261	R203-F261 WeakPolarHBondContact O-CD1 3.38Å
204	G	89.4	Confident	87.6	Confident	12 Å²	12	45.9 Å²	45.9	12%	0.124	24%	0.235	C	C	.	.			trans	-170.9	163.7	-175.4	0	0	0	0	0	110.2	K201 F260	K201-G204 WeakPolarHBondContact CG-O 3.17Å; G204-F260 CarbonylContact C-O 3.52Å; G204-F260 WeakPolarHBondContact CA-O 3.42Å
205	A	92.2	Very high	87.3	Confident	1 Å²	1	50.5 Å²	50.5	1%	0.008	25%	0.253	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.9	131.3	175.1	0	0	0	0	0	111.7	I198 K201 V210 E259 F260	I198-A205 HydrophobicContact CB-CB 4.38Å; I198-A205 HydrophobicContact CG1-CB 3.77Å; K201-A205 HydrophobicContact CB-CB 4.28Å; K201-A205 HydrophobicContact CG-CB 4.4Å; A205-V210 HydrophobicContact CB-CG2 3.81Å; A205-E259 WeakPolarHBondContact O-CA 3.22Å; A205-F260 PolarHBondContact N-O 3.3Å; A205-F260 PolarHBondContact O-N 3.09Å
206	R	91.8	Very high	86.6	Confident	117 Å²	117	55.8 Å²	55.8	44%	0.442	28%	0.28	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-56.9	139.1	171.8	-64.6	-172.5	-172.9	-168.8	10.2	110.9	S208 A209 V210 E257 E259	R206-S208 PolarHBondContact O-N 2.98Å; R206-A209 HydrophobicContact CB-CB 4.48Å; R206-A209 WeakPolarHBondContact O-CB 3.39Å; R206-A209 PolarHBondContact O-N 3.37Å; R206-V210 PolarHBondContact O-N 3.33Å; R206-V210 VanDerWaalsContact O-N 3.12Å; R206-E257 WeakPolarHBondContact CD-OE2 3.45Å; R206-E257 IonicContact CZ-OE2 3.57Å; R206-E257 IonicContact NE-OE2 3.83Å; R206-E257 IonicContact NH1-OE1 3.9Å; R206-E257 IonicContact NH1-OE2 3.62Å; R206-E257 PolarHBondContact NH1-OE2 3.18Å; R206-E259 HydrophobicContact CG-CG 4.04Å
207	E	92.1	Very high	86.1	Confident	31 Å²	31	56.7 Å²	56.7	15%	0.145	29%	0.285	C	S	.	.	H	α-helix	trans	-52.3	-44.4	-179.8	-163.3	-155.1	162.4	0	0	111.1	A209 V210 W211 Y247 Y258 F260	E207-A209 VanDerWaalsContact C-N 3.31Å; E207-A209 PolarHBondContact O-N 2.97Å; E207-V210 PolarHBondContact O-N 2.88Å; E207-W211 VanDerWaalsContact CG-NE1 3.32Å; E207-W211 PolarHBondContact O-N 3.02Å; E207-W211 PolarHBondContact OE1-NE1 3.46Å; E207-Y247 HydrophobicContact CG-CE2 4.11Å; E207-Y247 PolarHBondContact OE2-OH 3.17Å; E207-Y258 WeakPolarHBondContact CB-O 3.25Å; E207-Y258 PolarHBondContact N-O 3.12Å; E207-F260 HydrophobicContact CB-CE2 4.15Å; E207-F260 HydrophobicContact CG-CD2 4.46Å; E207-F260 HydrophobicContact CG-CE2 3.61Å; E207-F260 HydrophobicContact CG-CZ 4.21Å
208	S	89.9	Confident	85.5	Confident	79 Å²	79	55 Å²	55	55%	0.552	28%	0.276	S	S	*	.	H	α-helix	trans	-58.5	-39.1	177.1	58.5	0	0	0	0	113.3	R206 N212	R206-S208 PolarHBondContact O-N 2.98Å; S208-N212 WeakPolarHBondContact O-CB 3.47Å; S208-N212 PolarHBondContact O-N 3.35Å
209	A	88	Confident	84.9	Confident	38 Å²	38	55 Å²	55	31%	0.314	28%	0.276	S	S	.	.	H	α-helix	trans	-69.8	-42.1	178	0	0	0	0	0	111.3	R206 E207 N212 V213	R206-A209 HydrophobicContact CB-CB 4.48Å; R206-A209 WeakPolarHBondContact O-CB 3.39Å; R206-A209 PolarHBondContact O-N 3.37Å; E207-A209 VanDerWaalsContact C-N 3.31Å; E207-A209 PolarHBondContact O-N 2.97Å; A209-N212 PolarHBondContact O-N 2.86Å; A209-V213 PolarHBondContact O-N 3.34Å; A209-V213 VanDerWaalsContact O-N 3.14Å
210	V	90.2	Very high	84.3	Confident	0 Å²	0	59.1 Å²	59.1	0%	0	29%	0.291	C	S	.	.	H	α-helix	trans	-59.5	-50.6	175	179.5	0	0	0	0	110.2	I194 L197 A205 R206 E207 N212 V213 L214 F260	I194-V210 HydrophobicContact CG1-CG1 4.22Å; I194-V210 HydrophobicContact CG2-CG1 4.05Å; L197-V210 HydrophobicContact CD2-CB 4.26Å; L197-V210 HydrophobicContact CD2-CG2 4.02Å; A205-V210 HydrophobicContact CB-CG2 3.81Å; R206-V210 PolarHBondContact O-N 3.33Å; R206-V210 VanDerWaalsContact O-N 3.12Å; E207-V210 PolarHBondContact O-N 2.88Å; V210-N212 VanDerWaalsContact C-N 3.29Å; V210-N212 PolarHBondContact O-N 3.34Å; V210-V213 PolarHBondContact O-N 2.92Å; V210-L214 HydrophobicContact CG1-CD1 3.95Å; V210-L214 WeakPolarHBondContact O-CB 3.4Å; V210-L214 VanDerWaalsContact O-CD1 3.25Å; V210-L214 WeakPolarHBondContact O-CD1 3.17Å; V210-L214 PolarHBondContact O-N 3.14Å; V210-F260 HydrophobicContact CB-CD2 4.13Å; V210-F260 HydrophobicContact CB-CE2 4.3Å; V210-F260 HydrophobicContact CG1-CD2 4.39Å; V210-F260 HydrophobicContact CG1-CE2 4.39Å; V210-F260 HydrophobicContact CG2-CD2 3.76Å; V210-F260 HydrophobicContact CG2-CE2 4.42Å
211	W	89.7	Confident	83.7	Confident	18 Å²	18	56.5 Å²	56.5	7%	0.068	28%	0.276	C	S	.	.	H	α-helix	trans	-62.6	-34.4	178.6	-70.5	127.5	0	0	0	113.9	E207 L214 R215 P221 V231 R232 I235	E207-W211 VanDerWaalsContact CG-NE1 3.32Å; E207-W211 PolarHBondContact O-N 3.02Å; E207-W211 PolarHBondContact OE1-NE1 3.46Å; W211-L214 HydrophobicContact CE3-CB 4.41Å; W211-L214 HydrophobicContact CE3-CD2 4.02Å; W211-L214 HydrophobicContact CZ3-CD2 3.75Å; W211-L214 PolarHBondContact O-N 3.01Å; W211-R215 WeakPolarHBondContact O-CB 3.3Å; W211-R215 PolarHBondContact O-N 2.96Å; W211-P221 HydrophobicContact CD2-CB 3.91Å; W211-P221 HydrophobicContact CD2-CG 4.05Å; W211-P221 HydrophobicContact CE3-CB 3.64Å; W211-P221 HydrophobicContact CE3-CG 3.88Å; W211-P221 HydrophobicContact CG-CG 4.36Å; W211-P221 HydrophobicContact CH2-CB 4.19Å; W211-P221 HydrophobicContact CZ2-CB 4.39Å; W211-P221 HydrophobicContact CZ3-CB 3.78Å; W211-P221 HydrophobicContact CZ3-CG 4.48Å; W211-V231 HydrophobicContact CH2-CG1 4.36Å; W211-V231 HydrophobicContact CZ3-CG1 4Å; W211-R232 HydrophobicContact CH2-CB 4.17Å; W211-R232 HydrophobicContact CH2-CG 4.32Å; W211-R232 HydrophobicContact CZ2-CB 4.21Å; W211-R232 HydrophobicContact CZ2-CG 3.86Å; W211-I235 HydrophobicContact CH2-CB 4.18Å; W211-I235 HydrophobicContact CH2-CD1 3.61Å; W211-I235 HydrophobicContact CH2-CG1 4.38Å; W211-I235 HydrophobicContact CZ3-CD1 3.79Å
212	N	86.8	Confident	83.2	Confident	81 Å²	81	58.7 Å²	58.7	43%	0.433	28%	0.28	S	S	.	.	H	α-helix	trans	-66.5	-44.2	178.1	-168.3	38.1	0	0	0	111.7	S208 A209 V210 R215 I216	S208-N212 WeakPolarHBondContact O-CB 3.47Å; S208-N212 PolarHBondContact O-N 3.35Å; A209-N212 PolarHBondContact O-N 2.86Å; V210-N212 VanDerWaalsContact C-N 3.29Å; V210-N212 PolarHBondContact O-N 3.34Å; N212-R215 WeakPolarHBondContact O-CB 3.4Å; N212-R215 PolarHBondContact O-N 2.8Å; N212-I216 WeakPolarHBondContact O-CG1 3.28Å; N212-I216 PolarHBondContact O-N 3.48Å
213	V	82	Confident	82.9	Confident	46 Å²	46	61.8 Å²	61.8	28%	0.279	28%	0.283	S	S	.	.	H	α-helix	trans	-66.5	-42	176.4	175.8	0	0	0	0	110.8	L197 A209 V210 R215 I216 L217	L197-V213 HydrophobicContact CD1-CG2 3.98Å; L197-V213 HydrophobicContact CD2-CB 3.81Å; L197-V213 HydrophobicContact CD2-CG1 4.26Å; L197-V213 HydrophobicContact CD2-CG2 3.75Å; A209-V213 PolarHBondContact O-N 3.34Å; A209-V213 VanDerWaalsContact O-N 3.14Å; V210-V213 PolarHBondContact O-N 2.92Å; V213-R215 VanDerWaalsContact C-N 3.26Å; V213-R215 PolarHBondContact O-N 3.46Å; V213-I216 WeakPolarHBondContact O-CB 3.43Å; V213-I216 PolarHBondContact O-N 3.1Å; V213-I216 VanDerWaalsContact O-N 3.14Å; V213-L217 HydrophobicContact CG1-CD1 4.28Å; V213-L217 WeakPolarHBondContact O-CG 3.45Å; V213-L217 PolarHBondContact O-N 3.24Å; V213-L217 VanDerWaalsContact O-N 3.11Å
214	L	85.4	Confident	82.2	Confident	1 Å²	1	58.8 Å²	58.8	1%	0.005	28%	0.276	C	S	.	.	H	α-helix	trans	-61.1	-36.5	176.1	-93.8	65.2	0	0	0	112.1	L190 I194 V210 W211 I216 L217 G218 L219 V231 I235	L190-L214 HydrophobicContact CD1-CD2 4.1Å; L190-L214 HydrophobicContact CD1-CG 4.28Å; I194-L214 HydrophobicContact CD1-CD2 4.42Å; I194-L214 HydrophobicContact CG1-CD1 3.97Å; V210-L214 HydrophobicContact CG1-CD1 3.95Å; V210-L214 WeakPolarHBondContact O-CB 3.4Å; V210-L214 VanDerWaalsContact O-CD1 3.25Å; V210-L214 WeakPolarHBondContact O-CD1 3.17Å; V210-L214 PolarHBondContact O-N 3.14Å; W211-L214 HydrophobicContact CE3-CB 4.41Å; W211-L214 HydrophobicContact CE3-CD2 4.02Å; W211-L214 HydrophobicContact CZ3-CD2 3.75Å; W211-L214 PolarHBondContact O-N 3.01Å; L214-I216 VanDerWaalsContact C-N 3.33Å; L214-I216 PolarHBondContact O-N 3.07Å; L214-L217 CarbonylContact O-C 3.59Å; L214-L217 VanDerWaalsContact O-C 3.31Å; L214-L217 WeakPolarHBondContact O-CA 3.37Å; L214-L217 WeakPolarHBondContact O-CB 3.3Å; L214-L217 PolarHBondContact O-N 3.04Å; L214-L217 VanDerWaalsContact O-N 3.09Å; L214-G218 PolarHBondContact O-N 3.38Å; L214-L219 CarbonylContact C-O 3.55Å; L214-L219 VanDerWaalsContact C-O 3.24Å; L214-L219 HydrophobicContact CB-CB 4.13Å; L214-L219 HydrophobicContact CD2-CD1 4.49Å; L214-L219 HydrophobicContact CG-CB 4.41Å; L214-L219 HydrophobicContact CG-CD1 4.33Å; L214-L219 WeakPolarHBondContact O-CA 3.37Å; L214-L219 WeakPolarHBondContact O-CB 3.46Å; L214-L219 PolarHBondContact O-N 2.78Å; L214-V231 HydrophobicContact CD2-CG1 4.45Å; L214-I235 HydrophobicContact CD2-CD1 3.26Å
215	R	82.5	Confident	81.2	Confident	98 Å²	98	59.3 Å²	59.3	37%	0.37	28%	0.275	S	S	.	.	H	α-helix	trans	-61.4	-40.6	175.2	-173	-173.5	-59.9	157.6	1.3	112.2	W211 N212 V213 L217 G218 L219	W211-R215 WeakPolarHBondContact O-CB 3.3Å; W211-R215 PolarHBondContact O-N 2.96Å; N212-R215 WeakPolarHBondContact O-CB 3.4Å; N212-R215 PolarHBondContact O-N 2.8Å; V213-R215 VanDerWaalsContact C-N 3.26Å; V213-R215 PolarHBondContact O-N 3.46Å; R215-L217 VanDerWaalsContact C-N 3.26Å; R215-L217 PolarHBondContact O-N 2.62Å; R215-G218 PolarHBondContact O-N 2.81Å; R215-G218 VanDerWaalsContact O-N 3.11Å; R215-L219 WeakPolarHBondContact CA-O 3.22Å; R215-L219 PolarHBondContact N-O 3.38Å
216	I	77.1	Confident	79.9	Confident	111 Å²	111	63.7 Å²	63.7	57%	0.569	31%	0.306	S	S	*	.	H	α-helix	trans	-63.5	-37.3	175.1	-63.3	166.8	0	0	0	110.1	N212 V213 L214 G218	N212-I216 WeakPolarHBondContact O-CG1 3.28Å; N212-I216 PolarHBondContact O-N 3.48Å; V213-I216 WeakPolarHBondContact O-CB 3.43Å; V213-I216 PolarHBondContact O-N 3.1Å; V213-I216 VanDerWaalsContact O-N 3.14Å; L214-I216 VanDerWaalsContact C-N 3.33Å; L214-I216 PolarHBondContact O-N 3.07Å; I216-G218 PolarHBondContact O-N 3.37Å
217	L	75	Confident	78.6	Confident	20 Å²	20	59.1 Å²	59.1	11%	0.105	29%	0.291	C	S	.	.	T	Hydrogen-bonded Turn	trans	-78.8	15.4	174.5	-61.1	172.1	0	0	0	113.9	H103 W107 M193 V213 L214 R215 L219	H103-L217 VanDerWaalsContact CB-O 3.32Å; H103-L217 WeakPolarHBondContact CB-O 3.08Å; W107-L217 PolarHBondContact NE1-O 3.49Å; W107-L217 VanDerWaalsContact NE1-O 3.17Å; M193-L217 HydrophobicContact CE-CD1 3.93Å; M193-L217 HydrophobicContact CE-CD2 4.36Å; M193-L217 HydrophobicContact CG-CD1 3.39Å; M193-L217 HydrophobicContact SD-CD1 3.83Å; V213-L217 HydrophobicContact CG1-CD1 4.28Å; V213-L217 WeakPolarHBondContact O-CG 3.45Å; V213-L217 PolarHBondContact O-N 3.24Å; V213-L217 VanDerWaalsContact O-N 3.11Å; L214-L217 CarbonylContact O-C 3.59Å; L214-L217 VanDerWaalsContact O-C 3.31Å; L214-L217 WeakPolarHBondContact O-CA 3.37Å; L214-L217 WeakPolarHBondContact O-CB 3.3Å; L214-L217 PolarHBondContact O-N 3.04Å; L214-L217 VanDerWaalsContact O-N 3.09Å; R215-L217 VanDerWaalsContact C-N 3.26Å; R215-L217 PolarHBondContact O-N 2.62Å; L217-L219 VanDerWaalsContact C-N 3.27Å; L217-L219 PolarHBondContact O-N 2.84Å
218	G	74.6	Confident	77.4	Confident	1 Å²	1	58.4 Å²	58.4	1%	0.01	29%	0.288	C	S	.	.	T	Hydrogen-bonded Turn	trans	78.6	-1.2	177	0	0	0	0	0	115.5	L214 R215 I216	L214-G218 PolarHBondContact O-N 3.38Å; R215-G218 PolarHBondContact O-N 2.81Å; R215-G218 VanDerWaalsContact O-N 3.11Å; I216-G218 PolarHBondContact O-N 3.37Å
219	L	78.7	Confident	76.9	Confident	0 Å²	0	56.2 Å²	56.2	0%	0	28%	0.277	C	S	.	.			trans	-93.5	103.3	-179.5	-62.8	176	0	0	0	110.6	W107 L190 L214 R215 L217 F228 V231	W107-L219 HydrophobicContact CG-CD2 4.1Å; W107-L219 HydrophobicContact CZ2-CD1 3.98Å; L190-L219 HydrophobicContact CD1-CD1 3.31Å; L190-L219 HydrophobicContact CD2-CD1 4.13Å; L190-L219 HydrophobicContact CG-CD1 4.31Å; L214-L219 CarbonylContact C-O 3.55Å; L214-L219 VanDerWaalsContact C-O 3.24Å; L214-L219 HydrophobicContact CB-CB 4.13Å; L214-L219 HydrophobicContact CD2-CD1 4.49Å; L214-L219 HydrophobicContact CG-CB 4.41Å; L214-L219 HydrophobicContact CG-CD1 4.33Å; L214-L219 WeakPolarHBondContact O-CA 3.37Å; L214-L219 WeakPolarHBondContact O-CB 3.46Å; L214-L219 PolarHBondContact O-N 2.78Å; R215-L219 WeakPolarHBondContact CA-O 3.22Å; R215-L219 PolarHBondContact N-O 3.38Å; L217-L219 VanDerWaalsContact C-N 3.27Å; L217-L219 PolarHBondContact O-N 2.84Å; L219-F228 HydrophobicContact CD2-CD2 3.95Å; L219-F228 HydrophobicContact CD2-CE2 3.99Å; L219-V231 HydrophobicContact CD2-CG2 4.34Å
220	R	73.4	Confident	76.8	Confident	105 Å²	105	57.5 Å²	57.5	40%	0.396	28%	0.279	S	S	.	.			trans	-92.5	132.2	174.8	-61	-174	-174.5	-176.4	-0.2	110.8	K223 H225	R220-K223 HydrophobicContact CB-CB 4.12Å; R220-K223 PolarHBondContact O-N 3.34Å; R220-H225 PolarHBondContact N-NE2 2.78Å; R220-H225 PolarHBondContact O-NE2 3.13Å
221	P	71.7	Confident	76.5	Confident	10 Å²	10	57.5 Å²	57.5	7%	0.065	28%	0.279	C	S	.	.	T	Hydrogen-bonded Turn	trans	-68.7	-33.9	-177.3	20.5	-28.1	0	0	0	113.9	W211 R232	W211-P221 HydrophobicContact CD2-CB 3.91Å; W211-P221 HydrophobicContact CD2-CG 4.05Å; W211-P221 HydrophobicContact CE3-CB 3.64Å; W211-P221 HydrophobicContact CE3-CG 3.88Å; W211-P221 HydrophobicContact CG-CG 4.36Å; W211-P221 HydrophobicContact CH2-CB 4.19Å; W211-P221 HydrophobicContact CZ2-CB 4.39Å; W211-P221 HydrophobicContact CZ3-CB 3.78Å; W211-P221 HydrophobicContact CZ3-CG 4.48Å; P221-R232 HydrophobicContact CB-CB 4.48Å
222	W	72.8	Confident	76.5	Confident	189 Å²	189	62.9 Å²	62.9	72%	0.716	30%	0.299	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88	1.8	-178	33.2	80.1	0	0	0	114.4
223	K	72.8	Confident	76.5	Confident	103 Å²	103	63.9 Å²	63.9	45%	0.448	30%	0.3	S	S	.	.	S	Bend	trans	-109.7	122.2	178.7	-170.2	178.7	178.5	-173.4	0	108.6	R220 H225	R220-K223 HydrophobicContact CB-CB 4.12Å; R220-K223 PolarHBondContact O-N 3.34Å; K223-H225 PolarHBondContact O-CD2 3.46Å; K223-H225 PolarHBondContact O-N 3.08Å; K223-H225 VanDerWaalsContact O-N 3.15Å
224	K	70.2	Confident	76.9	Confident	173 Å²	173	61.8 Å²	61.8	75%	0.752	29%	0.287	S	S	*	.			trans	-62.4	117.2	165.8	-69.2	-176.9	-179.9	179.4	0	108.2	G229	K224-G229 CarbonylContact C-O 3.57Å; K224-G229 WeakPolarHBondContact CA-O 3.3Å
225	H	69.2	Low	77.1	Confident	23 Å²	23	61.7 Å²	61.7	11%	0.106	29%	0.286	C	S	.	.	B	Isolated β-bridge	trans	-81.2	136.1	170.5	-68.1	-96	0	0	0	107	R220 K223 T227 F228 G229 V231	R220-H225 PolarHBondContact N-NE2 2.78Å; R220-H225 PolarHBondContact O-NE2 3.13Å; K223-H225 PolarHBondContact O-CD2 3.46Å; K223-H225 PolarHBondContact O-N 3.08Å; K223-H225 VanDerWaalsContact O-N 3.15Å; H225-T227 PolarHBondContact O-N 2.97Å; H225-F228 HydrophobicContact CB-CB 4.39Å; H225-G229 PolarHBondContact N-O 3.46Å; H225-G229 WeakPolarHBondContact O-CA 3.27Å; H225-G229 PolarHBondContact O-N 3.18Å; H225-V231 WeakPolarHBondContact CD2-CG2 3.4Å
226	S	64.3	Low	77.5	Confident	93 Å²	93	58.3 Å²	58.3	65%	0.65	28%	0.276	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.7	-21.5	170	53.5	0	0	0	0	111.8
227	T	63.6	Low	78.1	Confident	21 Å²	21	57.8 Å²	57.8	13%	0.129	27%	0.272	C	S	.	.	T	Hydrogen-bonded Turn	trans	-95.9	-55	-167.5	-29.6	0	0	0	0	113.5	V111 H225	V111-T227 HydrophobicContact CB-CG2 3.13Å; V111-T227 HydrophobicContact CG1-CG2 3.58Å; V111-T227 HydrophobicContact CG2-CG2 3.25Å; H225-T227 PolarHBondContact O-N 2.97Å
228	F	68.5	Low	78.8	Confident	17 Å²	17	60.5 Å²	60.5	8%	0.075	28%	0.284	C	S	.	.	T	Hydrogen-bonded Turn	trans	-99.3	-5.1	179.8	-68.2	-66.5	0	0	0	113.4	W107 V111 P186 M187 L219 H225 D230 V231 L234	W107-F228 HydrophobicContact CB-CE2 3.79Å; W107-F228 AromaticContact CD2-CE2 3.74Å; W107-F228 HydrophobicContact CD2-CE2 3.74Å; W107-F228 HydrophobicContact CD2-CZ 4.04Å; W107-F228 AromaticContact CE3-CE2 3.72Å; W107-F228 HydrophobicContact CE3-CE2 3.72Å; W107-F228 AromaticContact CE3-CZ 3.5Å; W107-F228 HydrophobicContact CE3-CZ 3.5Å; W107-F228 AromaticContact CG-CE2 3.8Å; W107-F228 HydrophobicContact CG-CE2 3.8Å; W107-F228 HydrophobicContact CG-CZ 4.49Å; W107-F228 HydrophobicContact CZ3-CZ 4.02Å; V111-F228 HydrophobicContact CG2-CD1 4.39Å; V111-F228 HydrophobicContact CG2-CE1 3.92Å; V111-F228 HydrophobicContact CG2-CZ 4.05Å; P186-F228 HydrophobicContact CB-CE1 4.22Å; P186-F228 HydrophobicContact CB-CZ 4.22Å; P186-F228 HydrophobicContact CG-CE1 4.34Å; M187-F228 HydrophobicContact CG-CE1 4.34Å; L219-F228 HydrophobicContact CD2-CD2 3.95Å; L219-F228 HydrophobicContact CD2-CE2 3.99Å; H225-F228 HydrophobicContact CB-CB 4.39Å; F228-D230 PolarHBondContact O-N 3.42Å; F228-V231 HydrophobicContact CB-CG2 3.74Å; F228-V231 HydrophobicContact CD2-CG2 4.33Å; F228-V231 HydrophobicContact CG-CG2 4.37Å; F228-L234 HydrophobicContact CB-CD2 4.06Å; F228-L234 HydrophobicContact CD1-CD2 3.65Å; F228-L234 HydrophobicContact CE1-CD2 4.4Å; F228-L234 HydrophobicContact CG-CD2 4.1Å
229	G	78.3	Confident	79.6	Confident	32 Å²	32	60.5 Å²	60.5	33%	0.33	28%	0.283	S	S	.	.	B	Isolated β-bridge	trans	65.8	-128.8	-167.4	0	0	0	0	0	110.6	K224 H225 V231	K224-G229 CarbonylContact C-O 3.57Å; K224-G229 WeakPolarHBondContact CA-O 3.3Å; H225-G229 PolarHBondContact N-O 3.46Å; H225-G229 WeakPolarHBondContact O-CA 3.27Å; H225-G229 PolarHBondContact O-N 3.18Å; G229-V231 PolarHBondContact O-N 2.65Å
230	D	85.1	Confident	80.3	Confident	65 Å²	65	62.3 Å²	62.3	35%	0.348	30%	0.295	S	S	.	.			trans	-83.7	103	175.3	-169.2	-22.3	0	0	0	110.3	F228 R232 K233 L234	F228-D230 PolarHBondContact O-N 3.42Å; D230-R232 PolarHBondContact O-N 3.07Å; D230-R232 WeakPolarHBondContact OD1-CA 3.49Å; D230-R232 WeakPolarHBondContact OD1-CB 3.14Å; D230-R232 PolarHBondContact OD1-N 3.42Å; D230-K233 HydrophobicContact CB-CB 3.82Å; D230-K233 WeakPolarHBondContact O-CB 3.47Å; D230-K233 PolarHBondContact O-N 2.85Å; D230-K233 PolarHBondContact OD1-N 3.12Å; D230-L234 PolarHBondContact O-N 3.18Å
231	V	85.1	Confident	81.2	Confident	0 Å²	0	64.9 Å²	64.9	0%	0	31%	0.311	C	S	.	.	H	α-helix	trans	-63.2	-29.4	179.6	177.5	0	0	0	0	111.4	L190 W211 L214 L219 H225 F228 G229 I235	L190-V231 HydrophobicContact CD2-CG1 4.43Å; W211-V231 HydrophobicContact CH2-CG1 4.36Å; W211-V231 HydrophobicContact CZ3-CG1 4Å; L214-V231 HydrophobicContact CD2-CG1 4.45Å; L219-V231 HydrophobicContact CD2-CG2 4.34Å; H225-V231 WeakPolarHBondContact CD2-CG2 3.4Å; F228-V231 HydrophobicContact CB-CG2 3.74Å; F228-V231 HydrophobicContact CD2-CG2 4.33Å; F228-V231 HydrophobicContact CG-CG2 4.37Å; G229-V231 PolarHBondContact O-N 2.65Å; V231-I235 HydrophobicContact CG1-CD1 3.73Å; V231-I235 HydrophobicContact CG1-CG1 4.42Å; V231-I235 WeakPolarHBondContact O-CG1 3.32Å; V231-I235 PolarHBondContact O-N 3.28Å; V231-I235 VanDerWaalsContact O-N 3.14Å
232	R	88.5	Confident	82.1	Confident	132 Å²	132	67.8 Å²	67.8	50%	0.498	33%	0.325	S	S	.	.	H	α-helix	trans	-62.1	-53.6	174.1	-167.8	-177.7	-176.7	-169.1	-0.4	109.7	W211 P221 D230 L234 I235 T236	W211-R232 HydrophobicContact CH2-CB 4.17Å; W211-R232 HydrophobicContact CH2-CG 4.32Å; W211-R232 HydrophobicContact CZ2-CB 4.21Å; W211-R232 HydrophobicContact CZ2-CG 3.86Å; P221-R232 HydrophobicContact CB-CB 4.48Å; D230-R232 PolarHBondContact O-N 3.07Å; D230-R232 WeakPolarHBondContact OD1-CA 3.49Å; D230-R232 WeakPolarHBondContact OD1-CB 3.14Å; D230-R232 PolarHBondContact OD1-N 3.42Å; R232-L234 VanDerWaalsContact C-N 3.34Å; R232-L234 PolarHBondContact O-N 2.83Å; R232-I235 PolarHBondContact O-N 3.13Å; R232-I235 VanDerWaalsContact O-N 3.15Å; R232-T236 HydrophobicContact CG-CG2 4.42Å; R232-T236 PolarHBondContact O-N 3.21Å; R232-T236 PolarHBondContact O-OG1 2.97Å
233	K	88.6	Confident	83	Confident	102 Å²	102	62.7 Å²	62.7	44%	0.443	31%	0.312	S	S	.	.	H	α-helix	trans	-57.1	-46	177.6	-161.9	-178	-175.8	-177.5	0	112.2	D230 I235 E237 E238	D230-K233 HydrophobicContact CB-CB 3.82Å; D230-K233 WeakPolarHBondContact O-CB 3.47Å; D230-K233 PolarHBondContact O-N 2.85Å; D230-K233 PolarHBondContact OD1-N 3.12Å; K233-I235 VanDerWaalsContact C-N 3.28Å; K233-I235 PolarHBondContact O-N 3.19Å; K233-E237 VanDerWaalsContact CE-CD 3.49Å; K233-E237 WeakPolarHBondContact CE-OE2 3.46Å; K233-E237 HydrophobicContact CG-CB 4.24Å; K233-E237 VanDerWaalsContact CG-CD 3.4Å; K233-E237 HydrophobicContact CG-CG 4.05Å; K233-E237 WeakPolarHBondContact CG-OE1 3.34Å; K233-E237 WeakPolarHBondContact CG-OE2 3.38Å; K233-E237 IonicContact NZ-OE2 2.78Å; K233-E237 WeakPolarHBondContact O-CA 3.35Å; K233-E237 VanDerWaalsContact O-CB 3.23Å; K233-E237 WeakPolarHBondContact O-CB 3.32Å; K233-E237 PolarHBondContact O-N 3.09Å; K233-E238 PolarHBondContact O-N 3.35Å
234	L	88.5	Confident	83.9	Confident	1 Å²	1	58.6 Å²	58.6	1%	0.005	29%	0.293	C	S	.	.	I	π-helix	trans	-55	-43.3	177.5	177.8	65.3	0	0	0	112	M187 L190 F228 D230 R232 E238 F239	M187-L234 HydrophobicContact CE-CD1 3.97Å; M187-L234 HydrophobicContact CG-CD1 4.42Å; M187-L234 HydrophobicContact SD-CD1 4.24Å; L190-L234 HydrophobicContact CD2-CD2 3.82Å; F228-L234 HydrophobicContact CB-CD2 4.06Å; F228-L234 HydrophobicContact CD1-CD2 3.65Å; F228-L234 HydrophobicContact CE1-CD2 4.4Å; F228-L234 HydrophobicContact CG-CD2 4.1Å; D230-L234 PolarHBondContact O-N 3.18Å; R232-L234 VanDerWaalsContact C-N 3.34Å; R232-L234 PolarHBondContact O-N 2.83Å; L234-E238 HydrophobicContact CD1-CB 4.06Å; L234-E238 VanDerWaalsContact CD1-CD 3.46Å; L234-E238 HydrophobicContact CD1-CG 4.26Å; L234-E238 WeakPolarHBondContact CD1-OE2 3.46Å; L234-E238 WeakPolarHBondContact O-CB 3.42Å; L234-E238 PolarHBondContact O-N 2.93Å; L234-F239 HydrophobicContact CD1-CE1 4.17Å; L234-F239 HydrophobicContact CD1-CZ 4.38Å; L234-F239 HydrophobicContact CD2-CZ 4.45Å; L234-F239 HydrophobicContact CG-CE1 4.41Å; L234-F239 HydrophobicContact CG-CE2 4.45Å; L234-F239 HydrophobicContact CG-CZ 4.19Å; L234-F239 PolarHBondContact O-N 2.93Å
235	I	90.5	Very high	85	Confident	0 Å²	0	50.4 Å²	50.4	0%	0	26%	0.258	C	S	.	.	I	π-helix	trans	-82	-43.8	-175.6	-66.5	170.9	0	0	0	111.9	L190 I194 W211 L214 V231 R232 K233 F239 L245 F260	L190-I235 HydrophobicContact CD2-CD1 4.41Å; I194-I235 HydrophobicContact CD1-CD1 3.49Å; I194-I235 VanDerWaalsContact CD1-CD1 3.49Å; I194-I235 HydrophobicContact CD1-CG1 3.68Å; I194-I235 HydrophobicContact CD1-CG2 4.08Å; W211-I235 HydrophobicContact CH2-CB 4.18Å; W211-I235 HydrophobicContact CH2-CD1 3.61Å; W211-I235 HydrophobicContact CH2-CG1 4.38Å; W211-I235 HydrophobicContact CZ3-CD1 3.79Å; L214-I235 HydrophobicContact CD2-CD1 3.26Å; V231-I235 HydrophobicContact CG1-CD1 3.73Å; V231-I235 HydrophobicContact CG1-CG1 4.42Å; V231-I235 WeakPolarHBondContact O-CG1 3.32Å; V231-I235 PolarHBondContact O-N 3.28Å; V231-I235 VanDerWaalsContact O-N 3.14Å; R232-I235 PolarHBondContact O-N 3.13Å; R232-I235 VanDerWaalsContact O-N 3.15Å; K233-I235 VanDerWaalsContact C-N 3.28Å; K233-I235 PolarHBondContact O-N 3.19Å; I235-F239 HydrophobicContact CB-CD2 4.41Å; I235-F239 HydrophobicContact CG1-CD2 4.02Å; I235-F239 HydrophobicContact CG1-CE2 4.09Å; I235-L245 HydrophobicContact CG2-CD1 3.9Å; I235-F260 HydrophobicContact CG2-CE1 3.74Å; I235-F260 HydrophobicContact CG2-CE2 4.43Å; I235-F260 HydrophobicContact CG2-CZ 3.66Å
236	T	90.4	Very high	86.3	Confident	26 Å²	26	54.6 Å²	54.6	16%	0.16	28%	0.276	C	S	.	.	I	π-helix	trans	-84.2	-24.9	-174.6	57.8	0	0	0	0	113.2	R232 V240 Y247 F260	R232-T236 HydrophobicContact CG-CG2 4.42Å; R232-T236 PolarHBondContact O-N 3.21Å; R232-T236 PolarHBondContact O-OG1 2.97Å; T236-V240 WeakPolarHBondContact O-CB 3.47Å; T236-V240 WeakPolarHBondContact O-CG2 3.34Å; T236-Y247 HydrophobicContact CG2-CE2 4.38Å; T236-F260 HydrophobicContact CG2-CE1 4.27Å; T236-F260 HydrophobicContact CG2-CZ 3.93Å
237	E	90.2	Very high	87.7	Confident	101 Å²	101	53.2 Å²	53.2	47%	0.472	26%	0.257	S	S	.	.	I	π-helix	trans	-108.9	-65.1	179.5	-57.4	-179	-157.2	0	0	110.8	K233 F239 V240 Q241	K233-E237 VanDerWaalsContact CE-CD 3.49Å; K233-E237 WeakPolarHBondContact CE-OE2 3.46Å; K233-E237 HydrophobicContact CG-CB 4.24Å; K233-E237 VanDerWaalsContact CG-CD 3.4Å; K233-E237 HydrophobicContact CG-CG 4.05Å; K233-E237 WeakPolarHBondContact CG-OE1 3.34Å; K233-E237 WeakPolarHBondContact CG-OE2 3.38Å; K233-E237 IonicContact NZ-OE2 2.78Å; K233-E237 WeakPolarHBondContact O-CA 3.35Å; K233-E237 VanDerWaalsContact O-CB 3.23Å; K233-E237 WeakPolarHBondContact O-CB 3.32Å; K233-E237 PolarHBondContact O-N 3.09Å; E237-F239 PolarHBondContact O-N 3.34Å; E237-V240 PolarHBondContact O-N 2.9Å; E237-Q241 WeakPolarHBondContact O-CB 3.45Å; E237-Q241 PolarHBondContact O-N 3.43Å
238	E	90.1	Very high	89.1	Confident	76 Å²	76	57.8 Å²	57.8	36%	0.355	28%	0.277	S	S	.	.	I	π-helix	trans	-64.5	-49.8	-170.4	-58.7	178.8	-142.7	0	0	112.4	K233 L234 V240 Q241 M242	K233-E238 PolarHBondContact O-N 3.35Å; L234-E238 HydrophobicContact CD1-CB 4.06Å; L234-E238 VanDerWaalsContact CD1-CD 3.46Å; L234-E238 HydrophobicContact CD1-CG 4.26Å; L234-E238 WeakPolarHBondContact CD1-OE2 3.46Å; L234-E238 WeakPolarHBondContact O-CB 3.42Å; L234-E238 PolarHBondContact O-N 2.93Å; E238-V240 VanDerWaalsContact C-N 3.26Å; E238-V240 PolarHBondContact O-N 3.47Å; E238-Q241 PolarHBondContact O-N 2.91Å; E238-M242 WeakPolarHBondContact O-CB 3.18Å; E238-M242 VanDerWaalsContact O-CG 3.29Å; E238-M242 WeakPolarHBondContact O-CG 3.15Å; E238-M242 PolarHBondContact O-N 3.29Å
239	F	91.9	Very high	90.2	Very high	1 Å²	1	62.8 Å²	62.8	0%	0.004	30%	0.295	C	S	.	.	H	α-helix	trans	-66.7	-28.1	177.9	-69.2	-16.2	0	0	0	113.5	M187 L190 L191 I194 L234 I235 E237 M242 Y244 L245	M187-F239 HydrophobicContact CB-CE1 4.04Å; M187-F239 HydrophobicContact CB-CZ 4.09Å; M187-F239 WeakPolarHBondContact O-CZ 3.14Å; L190-F239 HydrophobicContact CD2-CE2 4.32Å; L190-F239 HydrophobicContact CG-CE2 4.16Å; L191-F239 HydrophobicContact CB-CE1 4.34Å; L191-F239 HydrophobicContact CB-CE2 4.02Å; L191-F239 HydrophobicContact CB-CZ 3.91Å; L191-F239 HydrophobicContact CD1-CD2 4.11Å; L191-F239 HydrophobicContact CD1-CE2 4.42Å; L191-F239 HydrophobicContact CD1-CG 4.23Å; I194-F239 HydrophobicContact CD1-CD2 4.26Å; I194-F239 HydrophobicContact CD1-CE2 4.09Å; L234-F239 HydrophobicContact CD1-CE1 4.17Å; L234-F239 HydrophobicContact CD1-CZ 4.38Å; L234-F239 HydrophobicContact CD2-CZ 4.45Å; L234-F239 HydrophobicContact CG-CE1 4.41Å; L234-F239 HydrophobicContact CG-CE2 4.45Å; L234-F239 HydrophobicContact CG-CZ 4.19Å; L234-F239 PolarHBondContact O-N 2.93Å; I235-F239 HydrophobicContact CB-CD2 4.41Å; I235-F239 HydrophobicContact CG1-CD2 4.02Å; I235-F239 HydrophobicContact CG1-CE2 4.09Å; E237-F239 PolarHBondContact O-N 3.34Å; F239-M242 HydrophobicContact CD1-CE 3.73Å; F239-M242 HydrophobicContact CE1-CE 4.14Å; F239-Y244 PolarHBondContact O-N 3.24Å; F239-L245 HydrophobicContact CB-CB 4.39Å; F239-L245 HydrophobicContact CB-CD1 3.82Å; F239-L245 HydrophobicContact CB-CG 4.08Å; F239-L245 HydrophobicContact CD2-CD1 3.99Å; F239-L245 HydrophobicContact CG-CD1 4.4Å; F239-L245 PolarHBondContact O-N 3.23Å
240	V	93.2	Very high	90.7	Very high	39 Å²	39	62.5 Å²	62.5	24%	0.236	29%	0.287	C	S	.	.	H	α-helix	trans	-76.1	-45	176	177.6	0	0	0	0	110.8	T236 E237 E238 M242 N243 L245	T236-V240 WeakPolarHBondContact O-CB 3.47Å; T236-V240 WeakPolarHBondContact O-CG2 3.34Å; E237-V240 PolarHBondContact O-N 2.9Å; E238-V240 VanDerWaalsContact C-N 3.26Å; E238-V240 PolarHBondContact O-N 3.47Å; V240-M242 VanDerWaalsContact C-N 3.3Å; V240-M242 PolarHBondContact O-N 3.42Å; V240-N243 WeakPolarHBondContact O-CA 3.33Å; V240-N243 PolarHBondContact O-N 3.23Å; V240-L245 WeakPolarHBondContact CA-O 3.07Å; V240-L245 HydrophobicContact CG2-CB 4.08Å
241	Q	92.7	Very high	90.8	Very high	158 Å²	158	63.2 Å²	63.2	74%	0.738	30%	0.295	S	S	*	.	H	α-helix	trans	-62.4	-38.2	176.5	-172.9	176.3	18.4	0	0	111.5	E237 E238 N243	E237-Q241 WeakPolarHBondContact O-CB 3.45Å; E237-Q241 PolarHBondContact O-N 3.43Å; E238-Q241 PolarHBondContact O-N 2.91Å; Q241-N243 PolarHBondContact O-N 3.22Å; Q241-N243 PolarHBondContact O-ND2 2.91Å; Q241-N243 VanDerWaalsContact O-ND2 3.13Å
242	M	90.2	Very high	90.9	Very high	71 Å²	71	74.5 Å²	74.5	35%	0.35	34%	0.339	S	S	.	.	T	Hydrogen-bonded Turn	trans	-72.8	1.5	172.3	-70.1	-157.7	-62.7	0	0	113.9	E238 F239 V240 Y244 R265	E238-M242 WeakPolarHBondContact O-CB 3.18Å; E238-M242 VanDerWaalsContact O-CG 3.29Å; E238-M242 WeakPolarHBondContact O-CG 3.15Å; E238-M242 PolarHBondContact O-N 3.29Å; F239-M242 HydrophobicContact CD1-CE 3.73Å; F239-M242 HydrophobicContact CE1-CE 4.14Å; V240-M242 VanDerWaalsContact C-N 3.3Å; V240-M242 PolarHBondContact O-N 3.42Å; M242-Y244 HydrophobicContact CB-CD2 3.58Å; M242-Y244 HydrophobicContact CB-CE2 3.98Å; M242-Y244 HydrophobicContact CE-CD2 3.72Å; M242-Y244 HydrophobicContact CE-CE2 3.76Å; M242-Y244 PolarHBondContact O-N 2.76Å; M242-Y244 HydrophobicContact SD-CD2 4.34Å; M242-Y244 HydrophobicContact SD-CE2 4.04Å; M242-R265 WeakPolarHBondContact O-CD 3.15Å
243	N	91.6	Very high	90.8	Very high	83 Å²	83	70.4 Å²	70.4	44%	0.444	33%	0.329	S	S	.	.	T	Hydrogen-bonded Turn	trans	58.9	24.2	-178.8	-68	-89.7	0	0	0	114.3	V240 Q241 G263 S264 R265	V240-N243 WeakPolarHBondContact O-CA 3.33Å; V240-N243 PolarHBondContact O-N 3.23Å; Q241-N243 PolarHBondContact O-N 3.22Å; Q241-N243 PolarHBondContact O-ND2 2.91Å; Q241-N243 VanDerWaalsContact O-ND2 3.13Å; N243-G263 CarbonylContact O-C 3.59Å; N243-G263 WeakPolarHBondContact O-CA 3.47Å; N243-S264 PolarHBondContact O-N 2.97Å; N243-R265 HydrophobicContact CB-CB 4.08Å; N243-R265 WeakPolarHBondContact O-CB 3.41Å; N243-R265 PolarHBondContact O-N 3.03Å
244	Y	90.7	Very high	90.7	Very high	17 Å²	17	72.8 Å²	72.8	7%	0.067	34%	0.341	C	S	.	.	S	Bend	trans	-83.5	-34.7	170.7	-74.9	-68.9	0	0	0	111.9	L191 F239 M242 G263 R265 A266 E269	L191-Y244 HydrophobicContact CD1-CG 4.28Å; L191-Y244 HydrophobicContact CD2-CD1 3.53Å; L191-Y244 HydrophobicContact CD2-CD2 3.84Å; L191-Y244 HydrophobicContact CD2-CE1 3.94Å; L191-Y244 HydrophobicContact CD2-CE2 4.22Å; L191-Y244 HydrophobicContact CD2-CG 3.47Å; L191-Y244 VanDerWaalsContact CD2-CG 3.47Å; F239-Y244 PolarHBondContact O-N 3.24Å; M242-Y244 HydrophobicContact CB-CD2 3.58Å; M242-Y244 HydrophobicContact CB-CE2 3.98Å; M242-Y244 HydrophobicContact CE-CD2 3.72Å; M242-Y244 HydrophobicContact CE-CE2 3.76Å; M242-Y244 PolarHBondContact O-N 2.76Å; M242-Y244 HydrophobicContact SD-CD2 4.34Å; M242-Y244 HydrophobicContact SD-CE2 4.04Å; Y244-G263 WeakPolarHBondContact O-CA 3.26Å; Y244-G263 PolarHBondContact O-N 3.43Å; Y244-R265 HydrophobicContact CD1-CB 4.25Å; Y244-R265 HydrophobicContact CD1-CG 4.14Å; Y244-R265 HydrophobicContact CE1-CB 4.4Å; Y244-R265 HydrophobicContact CE1-CG 3.79Å; Y244-R265 PolarHBondContact OH-NE 3.37Å; Y244-R265 PolarHBondContact OH-NH2 2.87Å; Y244-A266 HydrophobicContact CD1-CB 4.01Å; Y244-A266 WeakPolarHBondContact O-CB 3.16Å; Y244-E269 VanDerWaalsContact CE1-OE2 3.23Å; Y244-E269 WeakPolarHBondContact CE1-OE2 3.21Å; Y244-E269 PolarHBondContact OH-OE2 3.26Å
245	L	94.7	Very high	90.6	Very high	1 Å²	1	77 Å²	77	1%	0.005	37%	0.369	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-117.2	151.8	172.6	-64	176.7	0	0	0	109.8	L191 I194 L195 I198 I235 F239 V240 F260 F261	L191-L245 HydrophobicContact CD1-CD2 4.44Å; L191-L245 HydrophobicContact CD1-CG 4.21Å; I194-L245 HydrophobicContact CG2-CD1 3.95Å; I194-L245 HydrophobicContact CG2-CD2 4.01Å; L195-L245 HydrophobicContact CD2-CD2 3.67Å; L195-L245 HydrophobicContact CG-CD2 4.42Å; I198-L245 HydrophobicContact CD1-CD2 3.67Å; I235-L245 HydrophobicContact CG2-CD1 3.9Å; F239-L245 HydrophobicContact CB-CB 4.39Å; F239-L245 HydrophobicContact CB-CD1 3.82Å; F239-L245 HydrophobicContact CB-CG 4.08Å; F239-L245 HydrophobicContact CD2-CD1 3.99Å; F239-L245 HydrophobicContact CG-CD1 4.4Å; F239-L245 PolarHBondContact O-N 3.23Å; V240-L245 WeakPolarHBondContact CA-O 3.07Å; V240-L245 HydrophobicContact CG2-CB 4.08Å; L245-F260 HydrophobicContact CB-CD1 4.47Å; L245-F260 HydrophobicContact CD1-CD1 4.2Å; L245-F260 HydrophobicContact CD1-CE1 4.49Å; L245-F261 CarbonylContact C-O 3.58Å; L245-F261 WeakPolarHBondContact CA-O 3.28Å
246	K	94.7	Very high	90.5	Very high	111 Å²	111	80 Å²	80	48%	0.483	39%	0.388	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-112.5	132.4	162	-73.1	171.4	-178.6	-177.9	0	107.3	F260 F261	K246-F260 CarbonylContact O-C 3.17Å; K246-F260 WeakPolarHBondContact O-CA 3.29Å; K246-F261 HydrophobicContact CB-CB 4.11Å; K246-F261 PolarHBondContact N-O 3.41Å; K246-F261 PolarHBondContact O-N 3.03Å
247	Y	94.4	Very high	90.5	Very high	64 Å²	64	81.5 Å²	81.5	25%	0.251	39%	0.394	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.8	117.1	179.7	-175.9	-117.9	0	0	0	108.8	E207 T236 Y258 F260	E207-Y247 HydrophobicContact CG-CE2 4.11Å; E207-Y247 PolarHBondContact OE2-OH 3.17Å; T236-Y247 HydrophobicContact CG2-CE2 4.38Å; Y247-Y258 HydrophobicContact CD1-CD1 4.32Å; Y247-Y258 AromaticContact CE1-CD1 3.53Å; Y247-Y258 HydrophobicContact CE1-CD1 3.53Å; Y247-Y258 AromaticContact CE1-CE1 3.97Å; Y247-Y258 HydrophobicContact CE1-CE1 3.97Å; Y247-Y258 HydrophobicContact CE1-CG 4.08Å; Y247-Y258 HydrophobicContact CE2-CD1 4.09Å; Y247-Y258 AromaticContact CE2-CG 3.95Å; Y247-Y258 HydrophobicContact CE2-CG 3.95Å; Y247-Y258 VanDerWaalsContact CZ-CB 3.46Å; Y247-Y258 AromaticContact CZ-CD1 3.41Å; Y247-Y258 VanDerWaalsContact CZ-CD1 3.41Å; Y247-Y258 AromaticContact CZ-CG 3.45Å; Y247-Y258 VanDerWaalsContact CZ-CG 3.45Å; Y247-Y258 VanDerWaalsContact OH-CB 3.3Å; Y247-Y258 WeakPolarHBondContact OH-CB 3.32Å; Y247-Y258 WeakPolarHBondContact OH-CD1 3.4Å; Y247-Y258 WeakPolarHBondContact OH-CD2 3.37Å; Y247-F260 AromaticContact CD2-CD1 3.67Å; Y247-F260 HydrophobicContact CD2-CD1 3.67Å; Y247-F260 AromaticContact CD2-CE1 3.31Å; Y247-F260 HydrophobicContact CD2-CE1 3.31Å; Y247-F260 HydrophobicContact CD2-CE2 4.27Å; Y247-F260 HydrophobicContact CD2-CG 4.27Å; Y247-F260 AromaticContact CD2-CZ 3.66Å; Y247-F260 HydrophobicContact CD2-CZ 3.66Å; Y247-F260 HydrophobicContact CE2-CD1 4.47Å; Y247-F260 AromaticContact CE2-CE1 3.88Å; Y247-F260 HydrophobicContact CE2-CE1 3.88Å; Y247-F260 HydrophobicContact CE2-CE2 4.16Å; Y247-F260 AromaticContact CE2-CZ 3.71Å; Y247-F260 HydrophobicContact CE2-CZ 3.71Å; Y247-F260 HydrophobicContact CG-CD1 4.45Å; Y247-F260 HydrophobicContact CG-CE1 4.06Å
248	Q	92.3	Very high	90.6	Very high	117 Å²	117	80.6 Å²	80.6	55%	0.547	39%	0.387	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.6	139.8	-174.2	-168.1	177.9	18.5	0	0	110.5	Y258 E259 F261	Q248-Y258 WeakPolarHBondContact O-CA 3.49Å; Q248-E259 PolarHBondContact N-O 2.67Å; Q248-E259 PolarHBondContact O-N 2.74Å; Q248-F261 HydrophobicContact CB-CD2 4.47Å; Q248-F261 HydrophobicContact CB-CE2 4.08Å
249	R	91.8	Very high	90.8	Very high	122 Å²	122	79.3 Å²	79.3	46%	0.46	38%	0.381	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-71.4	135.5	169.8	-176.1	-178.9	171.7	-172.6	1.4	109.5	P251 Y258	R249-P251 WeakPolarHBondContact O-CD 3.13Å; R249-Y258 HydrophobicContact CB-CD1 3.95Å; R249-Y258 HydrophobicContact CB-CE1 3.82Å; R249-Y258 HydrophobicContact CG-CE1 4.3Å
250	V	89	Confident	90.9	Very high	25 Å²	25	79.3 Å²	79.3	15%	0.152	38%	0.38	C	S	.	.	P	Polyproline II helix	trans	-70	122.1	174	-173.9	0	0	0	0	108.9	V253 E257 E259	V250-V253 HydrophobicContact CB-CB 4.44Å; V250-V253 HydrophobicContact CB-CG2 4.2Å; V250-V253 HydrophobicContact CG1-CB 4.31Å; V250-V253 HydrophobicContact CG1-CG2 3.55Å; V250-E257 HydrophobicContact CB-CB 4.39Å; V250-E257 HydrophobicContact CG2-CB 4.21Å; V250-E257 PolarHBondContact N-O 3.31Å; V250-E259 HydrophobicContact CG2-CB 4.23Å; V250-E259 HydrophobicContact CG2-CG 3.52Å
251	P	88.6	Confident	91	Very high	81 Å²	81	79.4 Å²	79.4	53%	0.526	38%	0.378	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63	143.9	178.7	-22.9	34.6	0	0	0	111.9	R249 V253	R249-P251 WeakPolarHBondContact O-CD 3.13Å; P251-V253 PolarHBondContact O-N 2.83Å; P251-V253 VanDerWaalsContact O-N 3.15Å
252	Y	86.2	Confident	91	Very high	237 Å²	237	73.9 Å²	73.9	93%	0.929	35%	0.35	S	S	*	.	T	Hydrogen-bonded Turn	trans	60.8	19.3	170.9	-42.2	-71.7	0	0	0	116.3
253	V	87.2	Confident	91.1	Very high	46 Å²	46	70.5 Å²	70.5	28%	0.279	33%	0.334	S	S	.	.			trans	-106.8	130.1	174.8	179.6	0	0	0	0	110.2	V250 P251 P255 E257	V250-V253 HydrophobicContact CB-CB 4.44Å; V250-V253 HydrophobicContact CB-CG2 4.2Å; V250-V253 HydrophobicContact CG1-CB 4.31Å; V250-V253 HydrophobicContact CG1-CG2 3.55Å; P251-V253 PolarHBondContact O-N 2.83Å; P251-V253 VanDerWaalsContact O-N 3.15Å; V253-P255 CarbonylContact C-O 3.59Å; V253-E257 HydrophobicContact CG1-CB 4.14Å; V253-E257 HydrophobicContact CG1-CG 3.91Å
254	E	86.6	Confident	91.1	Very high	151 Å²	151	69.5 Å²	69.5	71%	0.706	33%	0.333	S	S	*	.	S	Bend	trans	-126.9	122.2	175	-168.6	61.3	-133.9	0	0	108.8	P256	E254-P256 WeakPolarHBondContact OE1-CD 3.29Å
255	P	86	Confident	91	Very high	91 Å²	91	73 Å²	73	59%	0.591	35%	0.346	S	S	*	.	S	Bend	cis	-69.2	162.5	5.9	30.1	-35.9	0	0	0	113.9	V253 E257	V253-P255 CarbonylContact C-O 3.59Å; P255-E257 PolarHBondContact O-N 3.31Å
256	P	88.4	Confident	90.7	Very high	62 Å²	62	73 Å²	73	40%	0.403	35%	0.346	S	S	.	.			trans	-57.2	111.4	-178.7	-24.2	34.7	0	0	0	111.7	E254 Y258	E254-P256 WeakPolarHBondContact OE1-CD 3.29Å; P256-Y258 HydrophobicContact CB-CE2 4.41Å
257	E	90.1	Very high	90.3	Very high	57 Å²	57	71.2 Å²	71.2	27%	0.266	35%	0.348	S	S	.	.			trans	-99.3	148.3	172.5	-71.5	-169.4	-155.1	0	0	110.6	R206 V250 V253 P255	R206-E257 WeakPolarHBondContact CD-OE2 3.45Å; R206-E257 IonicContact CZ-OE2 3.57Å; R206-E257 IonicContact NE-OE2 3.83Å; R206-E257 IonicContact NH1-OE1 3.9Å; R206-E257 IonicContact NH1-OE2 3.62Å; R206-E257 PolarHBondContact NH1-OE2 3.18Å; V250-E257 HydrophobicContact CB-CB 4.39Å; V250-E257 HydrophobicContact CG2-CB 4.21Å; V250-E257 PolarHBondContact N-O 3.31Å; V253-E257 HydrophobicContact CG1-CB 4.14Å; V253-E257 HydrophobicContact CG1-CG 3.91Å; P255-E257 PolarHBondContact O-N 3.31Å
258	Y	92.8	Very high	89.7	Confident	83 Å²	83	77.8 Å²	77.8	33%	0.325	37%	0.372	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.9	151	176.1	-63.1	-96.5	0	0	0	111	E207 Y247 Q248 R249 P256	E207-Y258 WeakPolarHBondContact CB-O 3.25Å; E207-Y258 PolarHBondContact N-O 3.12Å; Y247-Y258 HydrophobicContact CD1-CD1 4.32Å; Y247-Y258 AromaticContact CE1-CD1 3.53Å; Y247-Y258 HydrophobicContact CE1-CD1 3.53Å; Y247-Y258 AromaticContact CE1-CE1 3.97Å; Y247-Y258 HydrophobicContact CE1-CE1 3.97Å; Y247-Y258 HydrophobicContact CE1-CG 4.08Å; Y247-Y258 HydrophobicContact CE2-CD1 4.09Å; Y247-Y258 AromaticContact CE2-CG 3.95Å; Y247-Y258 HydrophobicContact CE2-CG 3.95Å; Y247-Y258 VanDerWaalsContact CZ-CB 3.46Å; Y247-Y258 AromaticContact CZ-CD1 3.41Å; Y247-Y258 VanDerWaalsContact CZ-CD1 3.41Å; Y247-Y258 AromaticContact CZ-CG 3.45Å; Y247-Y258 VanDerWaalsContact CZ-CG 3.45Å; Y247-Y258 VanDerWaalsContact OH-CB 3.3Å; Y247-Y258 WeakPolarHBondContact OH-CB 3.32Å; Y247-Y258 WeakPolarHBondContact OH-CD1 3.4Å; Y247-Y258 WeakPolarHBondContact OH-CD2 3.37Å; Q248-Y258 WeakPolarHBondContact O-CA 3.49Å; R249-Y258 HydrophobicContact CB-CD1 3.95Å; R249-Y258 HydrophobicContact CB-CE1 3.82Å; R249-Y258 HydrophobicContact CG-CE1 4.3Å; P256-Y258 HydrophobicContact CB-CE2 4.41Å
259	E	93.4	Very high	89.3	Confident	49 Å²	49	76.3 Å²	76.3	23%	0.229	37%	0.365	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-129.3	142.8	177.9	-75.5	-177.7	165.9	0	0	111	A205 R206 Q248 V250 F261	A205-E259 WeakPolarHBondContact O-CA 3.22Å; R206-E259 HydrophobicContact CG-CG 4.04Å; Q248-E259 PolarHBondContact N-O 2.67Å; Q248-E259 PolarHBondContact O-N 2.74Å; V250-E259 HydrophobicContact CG2-CB 4.23Å; V250-E259 HydrophobicContact CG2-CG 3.52Å; E259-F261 HydrophobicContact CB-CD2 4.47Å; E259-F261 HydrophobicContact CB-CE2 3.57Å; E259-F261 HydrophobicContact CB-CZ 3.75Å; E259-F261 WeakPolarHBondContact OE2-CZ 3.42Å
260	F	95.2	Very high	88.9	Confident	0 Å²	0	71.3 Å²	71.3	0%	0	35%	0.347	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-97.9	135.8	170.3	-68	-77.1	0	0	0	110.4	I198 G204 A205 E207 V210 I235 T236 L245 K246 Y247	I198-F260 HydrophobicContact CD1-CB 3.75Å; I198-F260 HydrophobicContact CG1-CB 4.3Å; G204-F260 CarbonylContact C-O 3.52Å; G204-F260 WeakPolarHBondContact CA-O 3.42Å; A205-F260 PolarHBondContact N-O 3.3Å; A205-F260 PolarHBondContact O-N 3.09Å; E207-F260 HydrophobicContact CB-CE2 4.15Å; E207-F260 HydrophobicContact CG-CD2 4.46Å; E207-F260 HydrophobicContact CG-CE2 3.61Å; E207-F260 HydrophobicContact CG-CZ 4.21Å; V210-F260 HydrophobicContact CB-CD2 4.13Å; V210-F260 HydrophobicContact CB-CE2 4.3Å; V210-F260 HydrophobicContact CG1-CD2 4.39Å; V210-F260 HydrophobicContact CG1-CE2 4.39Å; V210-F260 HydrophobicContact CG2-CD2 3.76Å; V210-F260 HydrophobicContact CG2-CE2 4.42Å; I235-F260 HydrophobicContact CG2-CE1 3.74Å; I235-F260 HydrophobicContact CG2-CE2 4.43Å; I235-F260 HydrophobicContact CG2-CZ 3.66Å; T236-F260 HydrophobicContact CG2-CE1 4.27Å; T236-F260 HydrophobicContact CG2-CZ 3.93Å; L245-F260 HydrophobicContact CB-CD1 4.47Å; L245-F260 HydrophobicContact CD1-CD1 4.2Å; L245-F260 HydrophobicContact CD1-CE1 4.49Å; K246-F260 CarbonylContact O-C 3.17Å; K246-F260 WeakPolarHBondContact O-CA 3.29Å; Y247-F260 AromaticContact CD2-CD1 3.67Å; Y247-F260 HydrophobicContact CD2-CD1 3.67Å; Y247-F260 AromaticContact CD2-CE1 3.31Å; Y247-F260 HydrophobicContact CD2-CE1 3.31Å; Y247-F260 HydrophobicContact CD2-CE2 4.27Å; Y247-F260 HydrophobicContact CD2-CG 4.27Å; Y247-F260 AromaticContact CD2-CZ 3.66Å; Y247-F260 HydrophobicContact CD2-CZ 3.66Å; Y247-F260 HydrophobicContact CE2-CD1 4.47Å; Y247-F260 AromaticContact CE2-CE1 3.88Å; Y247-F260 HydrophobicContact CE2-CE1 3.88Å; Y247-F260 HydrophobicContact CE2-CE2 4.16Å; Y247-F260 AromaticContact CE2-CZ 3.71Å; Y247-F260 HydrophobicContact CE2-CZ 3.71Å; Y247-F260 HydrophobicContact CG-CD1 4.45Å; Y247-F260 HydrophobicContact CG-CE1 4.06Å
261	F	94.6	Very high	88.5	Confident	41 Å²	41	71.8 Å²	71.8	18%	0.18	35%	0.351	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.4	162.7	173.6	-53.7	-97	0	0	0	109.8	R203 L245 K246 Q248 E259 G263	R203-F261 WeakPolarHBondContact O-CD1 3.38Å; L245-F261 CarbonylContact C-O 3.58Å; L245-F261 WeakPolarHBondContact CA-O 3.28Å; K246-F261 HydrophobicContact CB-CB 4.11Å; K246-F261 PolarHBondContact N-O 3.41Å; K246-F261 PolarHBondContact O-N 3.03Å; Q248-F261 HydrophobicContact CB-CD2 4.47Å; Q248-F261 HydrophobicContact CB-CE2 4.08Å; E259-F261 HydrophobicContact CB-CD2 4.47Å; E259-F261 HydrophobicContact CB-CE2 3.57Å; E259-F261 HydrophobicContact CB-CZ 3.75Å; E259-F261 WeakPolarHBondContact OE2-CZ 3.42Å; F261-G263 PolarHBondContact O-N 3.27Å
262	W	93	Very high	88.2	Confident	43 Å²	43	70.5 Å²	70.5	16%	0.163	34%	0.336	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-64.6	131.2	169.4	-78.5	46.6	0	0	0	110.1	L195 I198 A266 I270 I275	L195-W262 HydrophobicContact CB-CH2 4.41Å; L195-W262 HydrophobicContact CB-CZ2 3.73Å; L195-W262 HydrophobicContact CD2-CD2 3.77Å; L195-W262 HydrophobicContact CD2-CE3 4.36Å; L195-W262 HydrophobicContact CD2-CG 3.82Å; L195-W262 HydrophobicContact CD2-CZ2 4.4Å; L195-W262 PolarHBondContact O-NE1 2.95Å; I198-W262 VanDerWaalsContact CG2-CD1 3.49Å; W262-A266 HydrophobicContact CE3-CB 4Å; W262-I270 HydrophobicContact CH2-CB 4.39Å; W262-I270 HydrophobicContact CH2-CG2 3.93Å; W262-I270 HydrophobicContact CZ3-CB 4.2Å; W262-I270 HydrophobicContact CZ3-CG2 4.24Å; W262-I275 HydrophobicContact CH2-CD1 3.82Å; W262-I275 HydrophobicContact CH2-CG1 3.46Å; W262-I275 VanDerWaalsContact CH2-CG1 3.46Å; W262-I275 HydrophobicContact CZ2-CD1 3.81Å; W262-I275 HydrophobicContact CZ2-CG1 3.66Å
263	G	91.6	Very high	87.9	Confident	0 Å²	0	60.1 Å²	60.1	0%	0	30%	0.297	C	S	.	.			trans	-80.8	163.2	171.7	0	0	0	0	0	112	N243 Y244 F261 R265 A266 S267	N243-G263 CarbonylContact O-C 3.59Å; N243-G263 WeakPolarHBondContact O-CA 3.47Å; Y244-G263 WeakPolarHBondContact O-CA 3.26Å; Y244-G263 PolarHBondContact O-N 3.43Å; F261-G263 PolarHBondContact O-N 3.27Å; G263-R265 PolarHBondContact O-N 3.19Å; G263-A266 PolarHBondContact O-N 3.41Å; G263-S267 PolarHBondContact O-N 3.4Å; G263-S267 PolarHBondContact O-OG 3.27Å
264	S	91.1	Very high	87.5	Confident	62 Å²	62	59.9 Å²	59.9	43%	0.434	29%	0.293	S	S	.	.	H	α-helix	trans	-60.4	-33.4	-178.1	51	0	0	0	0	112.4	N243 R268	N243-S264 PolarHBondContact O-N 2.97Å; S264-R268 WeakPolarHBondContact O-CG 3.41Å; S264-R268 PolarHBondContact O-N 3.21Å
265	R	88.6	Confident	87.2	Confident	90 Å²	90	52.7 Å²	52.7	34%	0.34	26%	0.259	S	S	.	.	H	α-helix	trans	-70.8	-44.8	176.6	-168.2	177.8	-178	-174.7	-4.8	111.5	M242 N243 Y244 G263 S267 R268 E269	M242-R265 WeakPolarHBondContact O-CD 3.15Å; N243-R265 HydrophobicContact CB-CB 4.08Å; N243-R265 WeakPolarHBondContact O-CB 3.41Å; N243-R265 PolarHBondContact O-N 3.03Å; Y244-R265 HydrophobicContact CD1-CB 4.25Å; Y244-R265 HydrophobicContact CD1-CG 4.14Å; Y244-R265 HydrophobicContact CE1-CB 4.4Å; Y244-R265 HydrophobicContact CE1-CG 3.79Å; Y244-R265 PolarHBondContact OH-NE 3.37Å; Y244-R265 PolarHBondContact OH-NH2 2.87Å; G263-R265 PolarHBondContact O-N 3.19Å; R265-S267 VanDerWaalsContact C-N 3.33Å; R265-S267 PolarHBondContact O-N 2.72Å; R265-R268 PolarHBondContact O-N 3.23Å; R265-R268 VanDerWaalsContact O-N 3.13Å; R265-E269 HydrophobicContact CG-CG 4.27Å; R265-E269 VanDerWaalsContact CG-OE1 3.26Å; R265-E269 WeakPolarHBondContact CG-OE1 3.37Å; R265-E269 IonicContact CZ-OE1 3.4Å; R265-E269 IonicContact NE-OE1 2.74Å; R265-E269 PolarHBondContact NE-OE1 3.15Å; R265-E269 IonicContact NE-OE2 3.51Å; R265-E269 IonicContact NH2-OE1 2.72Å; R265-E269 PolarHBondContact NH2-OE1 2.75Å; R265-E269 WeakPolarHBondContact O-CB 3.45Å; R265-E269 PolarHBondContact O-N 2.93Å
266	A	88.6	Confident	86.8	Confident	0 Å²	0	48.4 Å²	48.4	0%	0	23%	0.231	C	C	.	.	H	α-helix	trans	-59.1	-45.1	176.1	0	0	0	0	0	111.6	L195 Y244 W262 G263 R268 E269 I270	L195-A266 HydrophobicContact CD1-CB 3.8Å; L195-A266 HydrophobicContact CD2-CB 3.78Å; L195-A266 HydrophobicContact CG-CB 4.48Å; Y244-A266 HydrophobicContact CD1-CB 4.01Å; Y244-A266 WeakPolarHBondContact O-CB 3.16Å; W262-A266 HydrophobicContact CE3-CB 4Å; G263-A266 PolarHBondContact O-N 3.41Å; A266-R268 PolarHBondContact O-N 3.13Å; A266-E269 PolarHBondContact O-N 2.6Å; A266-I270 WeakPolarHBondContact O-CA 3.38Å; A266-I270 WeakPolarHBondContact O-CB 3.5Å; A266-I270 PolarHBondContact O-N 3.04Å
267	S	86.3	Confident	86.2	Confident	75 Å²	75	48.4 Å²	48.4	52%	0.524	23%	0.226	S	C	.	.	H	α-helix	trans	-64.4	-22.3	178.3	-62.6	0	0	0	0	114.1	G263 R265	G263-S267 PolarHBondContact O-N 3.4Å; G263-S267 PolarHBondContact O-OG 3.27Å; R265-S267 VanDerWaalsContact C-N 3.33Å; R265-S267 PolarHBondContact O-N 2.72Å
268	R	83.2	Confident	85.6	Confident	202 Å²	202	45.8 Å²	45.8	76%	0.762	21%	0.214	S	C	*	.	H	α-helix	trans	-89.7	-39.8	176.7	-74.4	176.2	61.2	-120.1	-3.8	113	S264 R265 A266	S264-R268 WeakPolarHBondContact O-CG 3.41Å; S264-R268 PolarHBondContact O-N 3.21Å; R265-R268 PolarHBondContact O-N 3.23Å; R265-R268 VanDerWaalsContact O-N 3.13Å; A266-R268 PolarHBondContact O-N 3.13Å
269	E	82.9	Confident	84.7	Confident	85 Å²	85	42.3 Å²	42.3	40%	0.397	20%	0.2	S	C	.	.	H	α-helix	trans	-89	-26.1	-173.5	-68.8	-177.6	-166.9	0	0	113.1	Y244 R265 A266	Y244-E269 VanDerWaalsContact CE1-OE2 3.23Å; Y244-E269 WeakPolarHBondContact CE1-OE2 3.21Å; Y244-E269 PolarHBondContact OH-OE2 3.26Å; R265-E269 HydrophobicContact CG-CG 4.27Å; R265-E269 VanDerWaalsContact CG-OE1 3.26Å; R265-E269 WeakPolarHBondContact CG-OE1 3.37Å; R265-E269 IonicContact CZ-OE1 3.4Å; R265-E269 IonicContact NE-OE1 2.74Å; R265-E269 PolarHBondContact NE-OE1 3.15Å; R265-E269 IonicContact NE-OE2 3.51Å; R265-E269 IonicContact NH2-OE1 2.72Å; R265-E269 PolarHBondContact NH2-OE1 2.75Å; R265-E269 WeakPolarHBondContact O-CB 3.45Å; R265-E269 PolarHBondContact O-N 2.93Å; A266-E269 PolarHBondContact O-N 2.6Å
270	I	82.9	Confident	83.7	Confident	17 Å²	17	40.7 Å²	40.7	9%	0.087	20%	0.195	C	C	.	.			trans	-119.7	117.9	-172.2	-59.4	164.1	0	0	0	109	L192 L195 W262 A266 Q274 I275	L192-I270 HydrophobicContact CD2-CD1 3.72Å; L192-I270 HydrophobicContact CD2-CG1 4.16Å; L192-I270 HydrophobicContact CD2-CG2 3.74Å; L192-I270 HydrophobicContact CG-CD1 4.45Å; L195-I270 HydrophobicContact CD1-CD1 3.22Å; W262-I270 HydrophobicContact CH2-CB 4.39Å; W262-I270 HydrophobicContact CH2-CG2 3.93Å; W262-I270 HydrophobicContact CZ3-CB 4.2Å; W262-I270 HydrophobicContact CZ3-CG2 4.24Å; A266-I270 WeakPolarHBondContact O-CA 3.38Å; A266-I270 WeakPolarHBondContact O-CB 3.5Å; A266-I270 PolarHBondContact O-N 3.04Å; I270-Q274 HydrophobicContact CG2-CB 4.48Å; I270-I275 HydrophobicContact CG2-CD1 3.74Å; I270-I275 HydrophobicContact CG2-CG1 3.84Å
271	T	81.2	Confident	82.4	Confident	36 Å²	36	43.9 Å²	43.9	22%	0.221	21%	0.207	C	C	.	.			trans	-84.6	153.9	177.4	65.8	0	0	0	0	111	M273 Q274 I275 L304	T271-M273 PolarHBondContact O-N 2.84Å; T271-Q274 PolarHBondContact O-N 3.19Å; T271-Q274 VanDerWaalsContact O-N 3.1Å; T271-Q274 WeakPolarHBondContact OG1-CG 3.26Å; T271-Q274 PolarHBondContact OG1-N 3.47Å; T271-Q274 PolarHBondContact OG1-OE1 3.13Å; T271-I275 PolarHBondContact O-N 2.97Å; T271-L304 HydrophobicContact CG2-CD2 3.94Å
272	K	81.8	Confident	81	Confident	53 Å²	53	43.5 Å²	43.5	23%	0.23	21%	0.209	C	C	.	.	H	α-helix	trans	-57.2	-30.6	173.3	-66	-177.1	-168.8	156.1	0	112.3	Y199 I275 M276 E296 A297 E300	Y199-K272 HydrophobicContact CD2-CG 4.43Å; Y199-K272 HydrophobicContact CE2-CB 4.22Å; Y199-K272 HydrophobicContact CE2-CD 3.72Å; Y199-K272 HydrophobicContact CE2-CG 3.76Å; K272-I275 PolarHBondContact O-N 3Å; K272-M276 WeakPolarHBondContact O-CB 3.37Å; K272-M276 PolarHBondContact O-N 3.01Å; K272-E296 IonicContact NZ-OE1 2.68Å; K272-E296 PolarHBondContact NZ-OE1 3.38Å; K272-A297 HydrophobicContact CB-CB 3.87Å; K272-E300 WeakPolarHBondContact CD-OE2 3.23Å; K272-E300 WeakPolarHBondContact CE-OE2 3.36Å; K272-E300 IonicContact NZ-OE2 3.39Å; K272-E300 PolarHBondContact NZ-OE2 3.39Å
273	M	80.1	Confident	79.8	Confident	19 Å²	19	47 Å²	47	9%	0.094	23%	0.225	C	C	.	.	H	α-helix	trans	-63.9	-45.8	175.8	-172.3	56.3	72.4	0	0	111.9	T271 I275 M276 E277 Y294 A297 L298 A301	T271-M273 PolarHBondContact O-N 2.84Å; M273-I275 VanDerWaalsContact C-N 3.31Å; M273-I275 PolarHBondContact O-N 3.11Å; M273-M276 WeakPolarHBondContact O-CB 3.16Å; M273-M276 PolarHBondContact O-N 3.49Å; M273-E277 HydrophobicContact CG-CG 4.43Å; M273-E277 WeakPolarHBondContact O-CG 3.21Å; M273-E277 PolarHBondContact O-N 3.48Å; M273-E277 HydrophobicContact SD-CG 4.34Å; M273-Y294 HydrophobicContact CE-CE2 4.34Å; M273-Y294 HydrophobicContact SD-CE2 4Å; M273-A297 HydrophobicContact CE-CB 4.12Å; M273-L298 HydrophobicContact CE-CB 3.75Å; M273-L298 HydrophobicContact CE-CD1 3.72Å; M273-L298 HydrophobicContact CE-CG 4.37Å; M273-A301 HydrophobicContact CB-CB 4.28Å; M273-A301 HydrophobicContact CE-CB 4.35Å
274	Q	78.8	Confident	78.3	Confident	41 Å²	41	54.5 Å²	54.5	19%	0.192	26%	0.258	C	S	.	.	H	α-helix	trans	-61.5	-40.1	178.1	-72.7	170.1	-43.5	0	0	112.2	V179 I270 T271 M276 F278	V179-Q274 HydrophobicContact CG1-CB 4.41Å; V179-Q274 HydrophobicContact CG1-CG 4.38Å; I270-Q274 HydrophobicContact CG2-CB 4.48Å; T271-Q274 PolarHBondContact O-N 3.19Å; T271-Q274 VanDerWaalsContact O-N 3.1Å; T271-Q274 WeakPolarHBondContact OG1-CG 3.26Å; T271-Q274 PolarHBondContact OG1-N 3.47Å; T271-Q274 PolarHBondContact OG1-OE1 3.13Å; Q274-M276 VanDerWaalsContact C-N 3.31Å; Q274-M276 PolarHBondContact O-N 3.05Å; Q274-F278 VanDerWaalsContact O-CB 3.26Å; Q274-F278 WeakPolarHBondContact O-CB 3.43Å; Q274-F278 PolarHBondContact O-N 2.98Å
275	I	81.4	Confident	76.7	Confident	0 Å²	0	57 Å²	57	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-60.7	-43.7	173.1	-66.2	-63	0	0	0	111	L192 L195 Y199 W262 I270 T271 K272 M273 F278 L279	L192-I275 HydrophobicContact CD2-CD1 3.81Å; L195-I275 HydrophobicContact CB-CD1 4.02Å; Y199-I275 HydrophobicContact CD1-CB 4.49Å; Y199-I275 HydrophobicContact CD1-CG2 3.51Å; Y199-I275 HydrophobicContact CE1-CG2 4.26Å; Y199-I275 HydrophobicContact CG-CG2 3.87Å; W262-I275 HydrophobicContact CH2-CD1 3.82Å; W262-I275 HydrophobicContact CH2-CG1 3.46Å; W262-I275 VanDerWaalsContact CH2-CG1 3.46Å; W262-I275 HydrophobicContact CZ2-CD1 3.81Å; W262-I275 HydrophobicContact CZ2-CG1 3.66Å; I270-I275 HydrophobicContact CG2-CD1 3.74Å; I270-I275 HydrophobicContact CG2-CG1 3.84Å; T271-I275 PolarHBondContact O-N 2.97Å; K272-I275 PolarHBondContact O-N 3Å; M273-I275 VanDerWaalsContact C-N 3.31Å; M273-I275 PolarHBondContact O-N 3.11Å; I275-F278 WeakPolarHBondContact O-CB 3.36Å; I275-F278 PolarHBondContact O-N 2.94Å; I275-L279 HydrophobicContact CG2-CD1 3.81Å; I275-L279 HydrophobicContact CG2-CG 4.31Å; I275-L279 WeakPolarHBondContact O-CB 3.42Å; I275-L279 VanDerWaalsContact O-CG 3.29Å; I275-L279 WeakPolarHBondContact O-CG 3.41Å; I275-L279 PolarHBondContact O-N 3.37Å
276	M	78.1	Confident	75.1	Confident	2 Å²	2	57.7 Å²	57.7	1%	0.01	27%	0.271	C	S	.	.	H	α-helix	trans	-68.4	-42.5	-176.5	-165.6	54.5	174.3	0	0	112.1	K272 M273 Q274 F278 L279 A280 P287 W290 Y294 A297	K272-M276 WeakPolarHBondContact O-CB 3.37Å; K272-M276 PolarHBondContact O-N 3.01Å; M273-M276 WeakPolarHBondContact O-CB 3.16Å; M273-M276 PolarHBondContact O-N 3.49Å; Q274-M276 VanDerWaalsContact C-N 3.31Å; Q274-M276 PolarHBondContact O-N 3.05Å; M276-F278 VanDerWaalsContact C-N 3.32Å; M276-F278 PolarHBondContact O-N 2.88Å; M276-L279 PolarHBondContact O-N 2.74Å; M276-A280 WeakPolarHBondContact O-CB 3.41Å; M276-A280 PolarHBondContact O-N 3.18Å; M276-P287 HydrophobicContact CE-CB 4.09Å; M276-P287 WeakPolarHBondContact CE-O 3.27Å; M276-P287 HydrophobicContact CG-CB 4.5Å; M276-W290 HydrophobicContact CE-CB 3.74Å; M276-W290 HydrophobicContact CE-CD2 4.37Å; M276-W290 HydrophobicContact CE-CE3 3.82Å; M276-W290 HydrophobicContact CE-CG 4.41Å; M276-W290 HydrophobicContact SD-CE3 4.38Å; M276-Y294 HydrophobicContact CE-CD2 4.24Å; M276-Y294 HydrophobicContact CE-CG 4.41Å; M276-Y294 HydrophobicContact CG-CD2 3.74Å; M276-A297 HydrophobicContact CB-CB 4.49Å
277	E	75.6	Confident	73.6	Confident	62 Å²	62	59.1 Å²	59.1	29%	0.29	28%	0.28	S	S	.	.	H	α-helix	trans	-64.7	-35.9	173	-70.2	175	178.6	0	0	112.2	V179 M273 R281	V179-E277 WeakPolarHBondContact CG2-OE2 3.4Å; M273-E277 HydrophobicContact CG-CG 4.43Å; M273-E277 WeakPolarHBondContact O-CG 3.21Å; M273-E277 PolarHBondContact O-N 3.48Å; M273-E277 HydrophobicContact SD-CG 4.34Å; E277-R281 WeakPolarHBondContact O-CB 3.22Å; E277-R281 WeakPolarHBondContact O-CG 3.34Å; E277-R281 PolarHBondContact O-N 3.26Å; E277-R281 PolarHBondContact O-NE 2.94Å
278	F	75.9	Confident	72.2	Confident	2 Å²	2	60.6 Å²	60.6	1%	0.009	28%	0.279	C	S	.	.	H	α-helix	trans	-65	-48.2	172.7	177.2	-98.1	0	0	0	111.1	V150 L181 M193 S196 Q274 I275 M276 A280 R281 V282	V150-F278 HydrophobicContact CG1-CE2 3.88Å; V150-F278 HydrophobicContact CG1-CZ 4.02Å; L181-F278 HydrophobicContact CD1-CD2 4.24Å; M193-F278 HydrophobicContact CB-CE1 4.47Å; M193-F278 HydrophobicContact CB-CZ 4.49Å; M193-F278 HydrophobicContact CE-CE1 3.97Å; M193-F278 HydrophobicContact CE-CZ 3.64Å; M193-F278 HydrophobicContact SD-CE1 3.88Å; M193-F278 HydrophobicContact SD-CZ 4.16Å; S196-F278 VanDerWaalsContact OG-CD1 3.28Å; S196-F278 WeakPolarHBondContact OG-CD1 3Å; Q274-F278 VanDerWaalsContact O-CB 3.26Å; Q274-F278 WeakPolarHBondContact O-CB 3.43Å; Q274-F278 PolarHBondContact O-N 2.98Å; I275-F278 WeakPolarHBondContact O-CB 3.36Å; I275-F278 PolarHBondContact O-N 2.94Å; M276-F278 VanDerWaalsContact C-N 3.32Å; M276-F278 PolarHBondContact O-N 2.88Å; F278-A280 PolarHBondContact O-N 3.44Å; F278-R281 PolarHBondContact O-N 3.1Å; F278-V282 HydrophobicContact CD1-CG2 4.08Å; F278-V282 HydrophobicContact CD2-CG2 4.34Å; F278-V282 HydrophobicContact CE1-CG2 3.7Å; F278-V282 HydrophobicContact CE2-CG2 3.98Å; F278-V282 HydrophobicContact CG-CG2 4.4Å; F278-V282 HydrophobicContact CZ-CG2 3.66Å; F278-V282 VanDerWaalsContact O-CG2 3.3Å; F278-V282 WeakPolarHBondContact O-CG2 3.38Å; F278-V282 PolarHBondContact O-N 2.61Å
279	L	74.7	Confident	70.9	Confident	9 Å²	9	53.4 Å²	53.4	5%	0.047	26%	0.263	C	S	.	.	H	α-helix	trans	-59.7	-46.3	177.6	-76.6	170.4	0	0	0	112.1	Y199 V200 I275 M276 R281 V282 F283	Y199-L279 HydrophobicContact CD1-CD1 4.36Å; V200-L279 HydrophobicContact CG2-CD1 3.69Å; V200-L279 HydrophobicContact CG2-CD2 4.12Å; I275-L279 HydrophobicContact CG2-CD1 3.81Å; I275-L279 HydrophobicContact CG2-CG 4.31Å; I275-L279 WeakPolarHBondContact O-CB 3.42Å; I275-L279 VanDerWaalsContact O-CG 3.29Å; I275-L279 WeakPolarHBondContact O-CG 3.41Å; I275-L279 PolarHBondContact O-N 3.37Å; M276-L279 PolarHBondContact O-N 2.74Å; L279-R281 VanDerWaalsContact C-N 3.27Å; L279-R281 PolarHBondContact O-N 3.32Å; L279-V282 PolarHBondContact O-N 3.46Å; L279-F283 HydrophobicContact CB-CD2 4.47Å; L279-F283 HydrophobicContact CD2-CD2 3.98Å; L279-F283 HydrophobicContact CD2-CE2 3.56Å; L279-F283 WeakPolarHBondContact O-CB 3.47Å; L279-F283 VanDerWaalsContact O-CD2 3.3Å; L279-F283 WeakPolarHBondContact O-CD2 3.42Å; L279-F283 PolarHBondContact O-N 3.14Å
280	A	72.3	Confident	70	Confident	15 Å²	15	53 Å²	53	12%	0.124	26%	0.258	C	S	.	.	H	α-helix	trans	-57.2	-42.1	177.6	0	0	0	0	0	111.9	M276 F278 K284 K285 P287	M276-A280 WeakPolarHBondContact O-CB 3.41Å; M276-A280 PolarHBondContact O-N 3.18Å; F278-A280 PolarHBondContact O-N 3.44Å; A280-K284 VanDerWaalsContact O-CA 3.29Å; A280-K284 WeakPolarHBondContact O-CA 3.01Å; A280-K284 PolarHBondContact O-N 3.19Å; A280-K285 WeakPolarHBondContact CA-O 3.02Å; A280-K285 WeakPolarHBondContact CB-O 3.33Å; A280-K285 PolarHBondContact O-N 2.68Å; A280-P287 HydrophobicContact CB-CG 3.73Å
281	R	67.8	Low	69	Low	67 Å²	67	55 Å²	55	25%	0.253	27%	0.272	S	S	.	.	H	α-helix	trans	-67.8	-45.6	176.9	-80	-179	-76.4	179.9	-1.9	113.2	V179 E277 F278 L279	V179-R281 VanDerWaalsContact CG1-NH2 3.27Å; E277-R281 WeakPolarHBondContact O-CB 3.22Å; E277-R281 WeakPolarHBondContact O-CG 3.34Å; E277-R281 PolarHBondContact O-N 3.26Å; E277-R281 PolarHBondContact O-NE 2.94Å; F278-R281 PolarHBondContact O-N 3.1Å; L279-R281 VanDerWaalsContact C-N 3.27Å; L279-R281 PolarHBondContact O-N 3.32Å
282	V	66	Low	68.5	Low	34 Å²	34	57.6 Å²	57.6	21%	0.206	29%	0.292	C	S	.	.	H	α-helix	trans	-62.8	-44.8	179	172.6	0	0	0	0	111.2	V150 M193 F278 L279	V150-V282 HydrophobicContact CB-CG2 4.49Å; V150-V282 HydrophobicContact CG1-CG2 4.11Å; V150-V282 HydrophobicContact CG2-CG2 4.19Å; M193-V282 HydrophobicContact CE-CG1 4.42Å; M193-V282 HydrophobicContact CE-CG2 4.24Å; F278-V282 HydrophobicContact CD1-CG2 4.08Å; F278-V282 HydrophobicContact CD2-CG2 4.34Å; F278-V282 HydrophobicContact CE1-CG2 3.7Å; F278-V282 HydrophobicContact CE2-CG2 3.98Å; F278-V282 HydrophobicContact CG-CG2 4.4Å; F278-V282 HydrophobicContact CZ-CG2 3.66Å; F278-V282 VanDerWaalsContact O-CG2 3.3Å; F278-V282 WeakPolarHBondContact O-CG2 3.38Å; F278-V282 PolarHBondContact O-N 2.61Å; L279-V282 PolarHBondContact O-N 3.46Å
283	F	67.2	Low	67.9	Low	117 Å²	117	58.5 Å²	58.5	51%	0.513	29%	0.293	S	S	.	.	H	α-helix	trans	-89.8	-7.4	-175.1	-71.2	-71.5	0	0	0	114.4	L279 K285 W290	L279-F283 HydrophobicContact CB-CD2 4.47Å; L279-F283 HydrophobicContact CD2-CD2 3.98Å; L279-F283 HydrophobicContact CD2-CE2 3.56Å; L279-F283 WeakPolarHBondContact O-CB 3.47Å; L279-F283 VanDerWaalsContact O-CD2 3.3Å; L279-F283 WeakPolarHBondContact O-CD2 3.42Å; L279-F283 PolarHBondContact O-N 3.14Å; F283-K285 HydrophobicContact CB-CB 4.26Å; F283-K285 HydrophobicContact CB-CD 4.42Å; F283-K285 HydrophobicContact CB-CG 4.3Å; F283-K285 PolarHBondContact O-N 2.89Å; F283-K285 VanDerWaalsContact O-N 3.09Å; F283-W290 HydrophobicContact CB-CH2 4.11Å; F283-W290 AromaticContact CD2-CH2 3.93Å; F283-W290 HydrophobicContact CD2-CH2 3.93Å; F283-W290 HydrophobicContact CD2-CZ2 4.5Å; F283-W290 HydrophobicContact CG-CH2 4.19Å
284	K	60.1	Low	67.2	Low	156 Å²	156	60.4 Å²	60.4	68%	0.678	30%	0.3	S	S	*	.	T	Hydrogen-bonded Turn	trans	47.3	32.1	-168.4	-77.4	-143.9	174	-151.9	0	112.6	A280	A280-K284 VanDerWaalsContact O-CA 3.29Å; A280-K284 WeakPolarHBondContact O-CA 3.01Å; A280-K284 PolarHBondContact O-N 3.19Å
285	K	58.1	Low	66.8	Low	116 Å²	116	65.6 Å²	65.6	50%	0.504	32%	0.318	S	S	.	.			trans	-102.8	139.4	174.6	-79	-178.9	174	-72.8	0	107.2	A280 F283 A289 W290	A280-K285 WeakPolarHBondContact CA-O 3.02Å; A280-K285 WeakPolarHBondContact CB-O 3.33Å; A280-K285 PolarHBondContact O-N 2.68Å; F283-K285 HydrophobicContact CB-CB 4.26Å; F283-K285 HydrophobicContact CB-CD 4.42Å; F283-K285 HydrophobicContact CB-CG 4.3Å; F283-K285 PolarHBondContact O-N 2.89Å; F283-K285 VanDerWaalsContact O-N 3.09Å; K285-A289 HydrophobicContact CB-CB 3.92Å; K285-A289 HydrophobicContact CD-CB 4.23Å; K285-A289 HydrophobicContact CG-CB 4.47Å; K285-W290 HydrophobicContact CB-CH2 4.17Å; K285-W290 HydrophobicContact CB-CZ3 4.11Å; K285-W290 HydrophobicContact CD-CH2 4.2Å; K285-W290 HydrophobicContact CD-CZ2 4.42Å
286	D	54.9	Low	66.6	Low	103 Å²	103	69.2 Å²	69.2	55%	0.551	34%	0.335	S	S	*	.			trans	-52.6	136.9	168.8	-164.3	-63.6	0	0	0	108.2	Q288 A289	D286-Q288 HydrophobicContact CB-CB 4.41Å; D286-Q288 PolarHBondContact O-N 3.32Å; D286-Q288 WeakPolarHBondContact OD1-CB 3.37Å; D286-Q288 WeakPolarHBondContact OD1-CG 2.91Å; D286-Q288 PolarHBondContact OD1-N 3.33Å; D286-A289 WeakPolarHBondContact O-CB 3.49Å; D286-A289 PolarHBondContact O-N 2.96Å
287	P	56.5	Low	66.5	Low	30 Å²	30	69.1 Å²	69.1	20%	0.195	34%	0.335	C	S	.	.	G	3₁₀ helix	trans	-49.2	-29.1	170.8	-23.9	29.8	0	0	0	112.7	M276 A280 A289 W290 Y294	M276-P287 HydrophobicContact CE-CB 4.09Å; M276-P287 WeakPolarHBondContact CE-O 3.27Å; M276-P287 HydrophobicContact CG-CB 4.5Å; A280-P287 HydrophobicContact CB-CG 3.73Å; P287-A289 PolarHBondContact O-N 3.46Å; P287-A289 VanDerWaalsContact O-N 3.15Å; P287-W290 CarbonylContact O-C 3.59Å; P287-W290 PolarHBondContact O-N 3.5Å; P287-Y294 HydrophobicContact CB-CD2 3.35Å; P287-Y294 HydrophobicContact CB-CE2 3.58Å; P287-Y294 HydrophobicContact CB-CG 3.91Å; P287-Y294 HydrophobicContact CG-CD2 4.39Å; P287-Y294 HydrophobicContact CG-CE2 4.17Å
288	Q	55.8	Low	66.4	Low	106 Å²	106	68.6 Å²	68.6	50%	0.495	33%	0.333	S	S	.	.	G	3₁₀ helix	trans	-64.8	-7.8	171.8	-61	-62.1	-45	0	0	114.3	D286 W290 P291	D286-Q288 HydrophobicContact CB-CB 4.41Å; D286-Q288 PolarHBondContact O-N 3.32Å; D286-Q288 WeakPolarHBondContact OD1-CB 3.37Å; D286-Q288 WeakPolarHBondContact OD1-CG 2.91Å; D286-Q288 PolarHBondContact OD1-N 3.33Å; Q288-W290 PolarHBondContact O-N 2.79Å; Q288-P291 WeakPolarHBondContact O-CD 3.38Å; Q288-P291 WeakPolarHBondContact O-CG 3.02Å
289	A	57.9	Low	66.4	Low	51 Å²	51	73.7 Å²	73.7	42%	0.421	36%	0.357	S	S	.	.	G	3₁₀ helix	trans	-64.4	-17.6	166	0	0	0	0	0	112	K285 D286 P287	K285-A289 HydrophobicContact CB-CB 3.92Å; K285-A289 HydrophobicContact CD-CB 4.23Å; K285-A289 HydrophobicContact CG-CB 4.47Å; D286-A289 WeakPolarHBondContact O-CB 3.49Å; D286-A289 PolarHBondContact O-N 2.96Å; P287-A289 PolarHBondContact O-N 3.46Å; P287-A289 VanDerWaalsContact O-N 3.15Å
290	W	63.8	Low	66.6	Low	76 Å²	76	76.8 Å²	76.8	29%	0.288	37%	0.372	S	S	.	.	S	Bend	trans	-129.3	69.8	170	-50.9	-86.7	0	0	0	110.7	M276 F283 K285 P287 Q288 S292 R293 Y294	M276-W290 HydrophobicContact CE-CB 3.74Å; M276-W290 HydrophobicContact CE-CD2 4.37Å; M276-W290 HydrophobicContact CE-CE3 3.82Å; M276-W290 HydrophobicContact CE-CG 4.41Å; M276-W290 HydrophobicContact SD-CE3 4.38Å; F283-W290 HydrophobicContact CB-CH2 4.11Å; F283-W290 AromaticContact CD2-CH2 3.93Å; F283-W290 HydrophobicContact CD2-CH2 3.93Å; F283-W290 HydrophobicContact CD2-CZ2 4.5Å; F283-W290 HydrophobicContact CG-CH2 4.19Å; K285-W290 HydrophobicContact CB-CH2 4.17Å; K285-W290 HydrophobicContact CB-CZ3 4.11Å; K285-W290 HydrophobicContact CD-CH2 4.2Å; K285-W290 HydrophobicContact CD-CZ2 4.42Å; P287-W290 CarbonylContact O-C 3.59Å; P287-W290 PolarHBondContact O-N 3.5Å; Q288-W290 PolarHBondContact O-N 2.79Å; W290-S292 VanDerWaalsContact C-N 3.31Å; W290-S292 PolarHBondContact O-N 3.5Å; W290-R293 HydrophobicContact CB-CB 4.22Å; W290-R293 PolarHBondContact O-N 2.88Å; W290-R293 VanDerWaalsContact O-N 3.13Å; W290-Y294 PolarHBondContact O-N 3.14Å
291	P	61.8	Low	66.6	Low	60 Å²	60	77.7 Å²	77.7	39%	0.39	38%	0.379	S	S	.	.	H	α-helix	trans	-55.5	-43.3	-169	-19.6	27.2	0	0	0	113.2	Q288 R293 Y294 R295	Q288-P291 WeakPolarHBondContact O-CD 3.38Å; Q288-P291 WeakPolarHBondContact O-CG 3.02Å; P291-R293 PolarHBondContact O-N 3.43Å; P291-Y294 PolarHBondContact O-N 2.92Å; P291-R295 WeakPolarHBondContact O-CB 3.12Å; P291-R295 PolarHBondContact O-N 3.37Å
292	S	69.7	Low	66.8	Low	91 Å²	91	81.2 Å²	81.2	64%	0.636	39%	0.392	S	S	*	.	H	α-helix	trans	-64.7	-41.7	-177.9	-47.8	0	0	0	0	112.4	W290 E296	W290-S292 VanDerWaalsContact C-N 3.31Å; W290-S292 PolarHBondContact O-N 3.5Å; S292-E296 PolarHBondContact O-N 3.28Å; S292-E296 VanDerWaalsContact O-N 3.11Å
293	R	70.3	Confident	67.2	Low	71 Å²	71	82.2 Å²	82.2	27%	0.268	40%	0.404	S	S	.	.	H	α-helix	trans	-73.6	-37.9	179.6	-67.7	-69.4	-170.8	83.9	1.9	111.6	Y199 V200 W290 P291 E296 A297	Y199-R293 HydrophobicContact CE1-CB 4.4Å; Y199-R293 PolarHBondContact O-NH1 3.3Å; Y199-R293 PolarHBondContact O-NH2 3.14Å; V200-R293 PolarHBondContact O-NH2 3.4Å; W290-R293 HydrophobicContact CB-CB 4.22Å; W290-R293 PolarHBondContact O-N 2.88Å; W290-R293 VanDerWaalsContact O-N 3.13Å; P291-R293 PolarHBondContact O-N 3.43Å; R293-E296 PolarHBondContact O-N 3.45Å; R293-A297 WeakPolarHBondContact O-CB 3.11Å; R293-A297 PolarHBondContact O-N 3.41Å
294	Y	65.4	Low	67.4	Low	60 Å²	60	81.8 Å²	81.8	24%	0.235	41%	0.406	C	S	.	.	H	α-helix	trans	-64.2	-42.4	175.4	-173.8	-109.4	0	0	0	111.6	M273 M276 P287 W290 P291 A297 L298	M273-Y294 HydrophobicContact CE-CE2 4.34Å; M273-Y294 HydrophobicContact SD-CE2 4Å; M276-Y294 HydrophobicContact CE-CD2 4.24Å; M276-Y294 HydrophobicContact CE-CG 4.41Å; M276-Y294 HydrophobicContact CG-CD2 3.74Å; P287-Y294 HydrophobicContact CB-CD2 3.35Å; P287-Y294 HydrophobicContact CB-CE2 3.58Å; P287-Y294 HydrophobicContact CB-CG 3.91Å; P287-Y294 HydrophobicContact CG-CD2 4.39Å; P287-Y294 HydrophobicContact CG-CE2 4.17Å; W290-Y294 PolarHBondContact O-N 3.14Å; P291-Y294 PolarHBondContact O-N 2.92Å; Y294-A297 PolarHBondContact O-N 3.17Å; Y294-L298 WeakPolarHBondContact O-CB 3.38Å; Y294-L298 PolarHBondContact O-N 2.95Å
295	R	70.1	Confident	67.7	Low	149 Å²	149	84.6 Å²	84.6	56%	0.562	41%	0.413	S	S	*	.	H	α-helix	trans	-61.5	-48.1	176	-172.1	-176.7	-61.7	136	1.2	111.5	P291 A297 L298 E299	P291-R295 WeakPolarHBondContact O-CB 3.12Å; P291-R295 PolarHBondContact O-N 3.37Å; R295-A297 VanDerWaalsContact C-N 3.34Å; R295-A297 PolarHBondContact O-N 3.27Å; R295-L298 PolarHBondContact O-N 2.98Å; R295-L298 VanDerWaalsContact O-N 3.14Å; R295-E299 HydrophobicContact CG-CG 4.5Å; R295-E299 WeakPolarHBondContact CG-OE1 3.4Å; R295-E299 WeakPolarHBondContact O-CG 3.34Å; R295-E299 PolarHBondContact O-N 2.95Å
296	E	76.5	Confident	68.5	Low	77 Å²	77	86.3 Å²	86.3	36%	0.36	42%	0.423	S	S	.	.	H	α-helix	trans	-57.6	-46.5	176	-174.2	-166	172.2	0	0	111.5	K272 S292 R293 L298 E299 E300	K272-E296 IonicContact NZ-OE1 2.68Å; K272-E296 PolarHBondContact NZ-OE1 3.38Å; S292-E296 PolarHBondContact O-N 3.28Å; S292-E296 VanDerWaalsContact O-N 3.11Å; R293-E296 PolarHBondContact O-N 3.45Å; E296-L298 VanDerWaalsContact C-N 3.29Å; E296-L298 PolarHBondContact O-N 2.99Å; E296-E299 PolarHBondContact O-N 3.38Å; E296-E300 WeakPolarHBondContact O-CB 3.34Å; E296-E300 PolarHBondContact O-N 3.13Å
297	A	76.6	Confident	69.1	Low	0 Å²	0	85.1 Å²	85.1	0%	0	43%	0.427	C	S	.	.	H	α-helix	trans	-62.2	-36.8	177.5	0	0	0	0	0	112.4	K272 M273 M276 R293 Y294 R295 A301	K272-A297 HydrophobicContact CB-CB 3.87Å; M273-A297 HydrophobicContact CE-CB 4.12Å; M276-A297 HydrophobicContact CB-CB 4.49Å; R293-A297 WeakPolarHBondContact O-CB 3.11Å; R293-A297 PolarHBondContact O-N 3.41Å; Y294-A297 PolarHBondContact O-N 3.17Å; R295-A297 VanDerWaalsContact C-N 3.34Å; R295-A297 PolarHBondContact O-N 3.27Å; A297-A301 WeakPolarHBondContact O-CB 3.4Å; A297-A301 PolarHBondContact O-N 2.87Å
298	L	73.3	Confident	69.2	Low	51 Å²	51	88.7 Å²	88.7	27%	0.267	44%	0.444	S	S	.	.	H	α-helix	trans	-71.8	-41.2	178.5	-172.5	64.5	0	0	0	112.2	M273 Y294 R295 E296 A301 R302	M273-L298 HydrophobicContact CE-CB 3.75Å; M273-L298 HydrophobicContact CE-CD1 3.72Å; M273-L298 HydrophobicContact CE-CG 4.37Å; Y294-L298 WeakPolarHBondContact O-CB 3.38Å; Y294-L298 PolarHBondContact O-N 2.95Å; R295-L298 PolarHBondContact O-N 2.98Å; R295-L298 VanDerWaalsContact O-N 3.14Å; E296-L298 VanDerWaalsContact C-N 3.29Å; E296-L298 PolarHBondContact O-N 2.99Å; L298-A301 PolarHBondContact O-N 3.31Å; L298-R302 WeakPolarHBondContact O-CB 3.47Å; L298-R302 VanDerWaalsContact O-CG 3.25Å; L298-R302 WeakPolarHBondContact O-CG 3.48Å; L298-R302 PolarHBondContact O-N 2.94Å
299	E	76.3	Confident	69	Low	109 Å²	109	88.5 Å²	88.5	51%	0.509	45%	0.452	S	S	.	.	H	α-helix	trans	-62.8	-43.3	174.2	-73.3	170.6	-172.4	0	0	111	R295 E296 R302 A303	R295-E299 HydrophobicContact CG-CG 4.5Å; R295-E299 WeakPolarHBondContact CG-OE1 3.4Å; R295-E299 WeakPolarHBondContact O-CG 3.34Å; R295-E299 PolarHBondContact O-N 2.95Å; E296-E299 PolarHBondContact O-N 3.38Å; E299-R302 PolarHBondContact O-N 3.42Å; E299-A303 WeakPolarHBondContact O-CB 3.44Å; E299-A303 PolarHBondContact O-N 3.38Å
300	E	77.9	Confident	68.8	Low	74 Å²	74	92.1 Å²	92.1	35%	0.346	47%	0.469	S	S	.	.	H	α-helix	trans	-64.6	-42	175.6	-173.2	172.5	133.7	0	0	112.4	K272 E296 R302 A303 L304	K272-E300 WeakPolarHBondContact CD-OE2 3.23Å; K272-E300 WeakPolarHBondContact CE-OE2 3.36Å; K272-E300 IonicContact NZ-OE2 3.39Å; K272-E300 PolarHBondContact NZ-OE2 3.39Å; E296-E300 WeakPolarHBondContact O-CB 3.34Å; E296-E300 PolarHBondContact O-N 3.13Å; E300-R302 VanDerWaalsContact C-N 3.33Å; E300-R302 PolarHBondContact O-N 3.47Å; E300-A303 PolarHBondContact O-N 2.87Å; E300-L304 WeakPolarHBondContact O-CB 3.34Å; E300-L304 PolarHBondContact O-N 3.36Å
301	A	71.7	Confident	68	Low	34 Å²	34	92.5 Å²	92.5	28%	0.281	49%	0.489	S	S	.	.	H	α-helix	trans	-64.8	-37.1	176.2	0	0	0	0	0	112.2	M273 A297 L298 R305	M273-A301 HydrophobicContact CB-CB 4.28Å; M273-A301 HydrophobicContact CE-CB 4.35Å; A297-A301 WeakPolarHBondContact O-CB 3.4Å; A297-A301 PolarHBondContact O-N 2.87Å; L298-A301 PolarHBondContact O-N 3.31Å; A301-R305 WeakPolarHBondContact O-CB 3.25Å; A301-R305 PolarHBondContact O-N 2.88Å; A301-R305 VanDerWaalsContact O-N 3.08Å
302	R	73.8	Confident	67.1	Low	141 Å²	141	98.1 Å²	98.1	53%	0.532	51%	0.51	S	S	.	.	H	α-helix	trans	-65.8	-48.3	173.4	-73.8	173.2	-172.2	176.2	1.2	111.1	L298 E299 E300 L304 R305 E306	L298-R302 WeakPolarHBondContact O-CB 3.47Å; L298-R302 VanDerWaalsContact O-CG 3.25Å; L298-R302 WeakPolarHBondContact O-CG 3.48Å; L298-R302 PolarHBondContact O-N 2.94Å; E299-R302 PolarHBondContact O-N 3.42Å; E300-R302 VanDerWaalsContact C-N 3.33Å; E300-R302 PolarHBondContact O-N 3.47Å; R302-L304 VanDerWaalsContact C-N 3.3Å; R302-L304 PolarHBondContact O-N 3.36Å; R302-R305 WeakPolarHBondContact O-CB 3.24Å; R302-R305 PolarHBondContact O-N 2.88Å; R302-R305 VanDerWaalsContact O-N 3.09Å; R302-E306 WeakPolarHBondContact O-CG 3.43Å; R302-E306 PolarHBondContact O-N 3.49Å
303	A	74.2	Confident	65.7	Low	55 Å²	55	103.5 Å²	103.5	46%	0.455	52%	0.517	S	S	.	.	H	α-helix	trans	-59.5	-40.5	177.5	0	0	0	0	0	111.9	E299 E300 R305 E306 A307	E299-A303 WeakPolarHBondContact O-CB 3.44Å; E299-A303 PolarHBondContact O-N 3.38Å; E300-A303 PolarHBondContact O-N 2.87Å; A303-R305 VanDerWaalsContact C-N 3.34Å; A303-R305 PolarHBondContact O-N 3.35Å; A303-E306 PolarHBondContact O-N 3.09Å; A303-A307 VanDerWaalsContact O-CB 3.24Å; A303-A307 WeakPolarHBondContact O-CB 3.44Å; A303-A307 PolarHBondContact O-N 3.08Å
304	L	70.2	Confident	64.5	Low	107 Å²	107	105.9 Å²	105.9	56%	0.56	54%	0.542	S	S	*	.	H	α-helix	trans	-66.2	-36.1	176.3	-172.9	64.4	0	0	0	112.2	T271 E300 R302 N308	T271-L304 HydrophobicContact CG2-CD2 3.94Å; E300-L304 WeakPolarHBondContact O-CB 3.34Å; E300-L304 PolarHBondContact O-N 3.36Å; R302-L304 VanDerWaalsContact C-N 3.3Å; R302-L304 PolarHBondContact O-N 3.36Å; L304-N308 PolarHBondContact O-N 3.41Å
305	R	67.5	Low	63.4	Low	215 Å²	215	114.2 Å²	114.2	81%	0.811	57%	0.573	S	S	*	*	H	α-helix	trans	-70.5	-40.9	176.1	-171.7	177.5	-179.2	167.5	0.3	111.8	A301 R302 A303 A307 N308	A301-R305 WeakPolarHBondContact O-CB 3.25Å; A301-R305 PolarHBondContact O-N 2.88Å; A301-R305 VanDerWaalsContact O-N 3.08Å; R302-R305 WeakPolarHBondContact O-CB 3.24Å; R302-R305 PolarHBondContact O-N 2.88Å; R302-R305 VanDerWaalsContact O-N 3.09Å; A303-R305 VanDerWaalsContact C-N 3.34Å; A303-R305 PolarHBondContact O-N 3.35Å; R305-A307 VanDerWaalsContact C-N 3.33Å; R305-N308 PolarHBondContact O-N 3.24Å
306	E	74.6	Confident	62.1	Low	153 Å²	153	111.9 Å²	111.9	72%	0.715	58%	0.579	S	S	*	*	H	α-helix	trans	-67.5	-34.9	175.5	-71.4	171.9	-171.2	0	0	111.8	R302 A303 N308	R302-E306 WeakPolarHBondContact O-CG 3.43Å; R302-E306 PolarHBondContact O-N 3.49Å; A303-E306 PolarHBondContact O-N 3.09Å; E306-N308 PolarHBondContact O-N 3.29Å
307	A	67	Low	60.6	Low	77 Å²	77	113.4 Å²	113.4	64%	0.636	60%	0.599	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.1	-9.5	174.2	0	0	0	0	0	114	A303 R305 P309	A303-A307 VanDerWaalsContact O-CB 3.24Å; A303-A307 WeakPolarHBondContact O-CB 3.44Å; A303-A307 PolarHBondContact O-N 3.08Å; R305-A307 VanDerWaalsContact C-N 3.33Å; A307-P309 WeakPolarHBondContact O-CD 3.1Å
308	N	57.9	Low	59.1	Low	105 Å²	105	119.1 Å²	119.1	56%	0.561	63%	0.633	S	S	*	*			trans	-112.1	70.3	179	-164.9	13.3	0	0	0	112.5	L304 R305 E306 T310	L304-N308 PolarHBondContact O-N 3.41Å; R305-N308 PolarHBondContact O-N 3.24Å; E306-N308 PolarHBondContact O-N 3.29Å; N308-T310 VanDerWaalsContact C-N 3.28Å; N308-T310 PolarHBondContact O-N 3.32Å; N308-T310 PolarHBondContact OD1-OG1 3.04Å
309	P	52.4	Low	58	Low	102 Å²	102	121.8 Å²	121.8	66%	0.662	66%	0.656	S	S	*	*	G	3₁₀ helix	trans	-78.3	3	-178.7	29.9	-33.9	0	0	0	115.1	A307 A311	A307-P309 WeakPolarHBondContact O-CD 3.1Å; P309-A311 PolarHBondContact O-N 3.03Å
310	T	53.2	Low	56.3	Low	127 Å²	127	125.6 Å²	125.6	78%	0.779	67%	0.674	S	S	*	*	G	3₁₀ helix	trans	-74.9	7	-172.8	45.5	0	0	0	0	115.8	N308	N308-T310 VanDerWaalsContact C-N 3.28Å; N308-T310 PolarHBondContact O-N 3.32Å; N308-T310 PolarHBondContact OD1-OG1 3.04Å
311	A	47.8	Very low	54.8	Low	85 Å²	85	133.1 Å²	133.1	70%	0.702	72%	0.717	S	S	*	*	G	3₁₀ helix	trans	-92.2	-1.4	174.9	0	0	0	0	0	114.7	P309 Y313	P309-A311 PolarHBondContact O-N 3.03Å; A311-Y313 VanDerWaalsContact C-N 3.32Å; A311-Y313 PolarHBondContact O-N 2.99Å
312	H	42.6	Very low	54	Low	178 Å²	178	138.1 Å²	138.1	82%	0.824	74%	0.739	S	S	*	*			trans	-80.6	84.9	173.5	-126.1	-62.6	0	0	0	110.1
313	Y	41.5	Very low	53	Low	203 Å²	203	137.9 Å²	137.9	80%	0.796	75%	0.749	S	S	*	*			trans	-48	130.2	163.5	-93.4	-98.8	0	0	0	109.2	A311 R315	A311-Y313 VanDerWaalsContact C-N 3.32Å; A311-Y313 PolarHBondContact O-N 2.99Å; Y313-R315 PolarHBondContact O-N 2.97Å
314	P	45	Very low	51.8	Low	121 Å²	121	142.6 Å²	142.6	79%	0.786	77%	0.766	S	S	*	*			trans	-64.4	109.3	168.5	26.1	-29.6	0	0	0	106.7	S316	P314-S316 PolarHBondContact O-N 2.93Å
315	R	42.3	Very low	50.7	Low	236 Å²	236	144.6 Å²	144.6	89%	0.891	78%	0.778	S	S	*	*			trans	-51.9	110.4	171.5	-165.9	178.5	-156.8	137.1	1.1	106.4	Y313 S317	Y313-R315 PolarHBondContact O-N 2.97Å; R315-S317 PolarHBondContact O-N 2.87Å
316	S	42.7	Very low	49.6	Very low	99 Å²	99	140.3 Å²	140.3	69%	0.692	78%	0.776	S	S	*	*			trans	-49.6	102.5	169.7	48.3	0	0	0	0	108.3	P314 V318	P314-S316 PolarHBondContact O-N 2.93Å; S316-V318 PolarHBondContact O-N 2.97Å
317	S	44.7	Very low	48	Very low	110 Å²	110	139.4 Å²	139.4	77%	0.769	78%	0.78	S	S	*	*			trans	-65.1	89.7	161.4	38.8	0	0	0	0	106.3	R315 S319	R315-S317 PolarHBondContact O-N 2.87Å; S317-S319 VanDerWaalsContact C-N 3.35Å; S317-S319 PolarHBondContact O-N 3.14Å; S317-S319 VanDerWaalsContact O-N 3.14Å
318	V	44.2	Very low	46.6	Very low	119 Å²	119	143.9 Å²	143.9	72%	0.721	79%	0.79	S	S	*	*			trans	-65.5	103.5	159.6	170.5	0	0	0	0	104.7	S316 E320	S316-V318 PolarHBondContact O-N 2.97Å; V318-E320 PolarHBondContact O-N 3.23Å
319	S	51.2	Low	45.8	Very low	107 Å²	107	146.8 Å²	146.8	75%	0.748	81%	0.808	S	S	*	*			trans	-64.6	112	168.3	-62.4	0	0	0	0	107.8	S317 D321	S317-S319 VanDerWaalsContact C-N 3.35Å; S317-S319 PolarHBondContact O-N 3.14Å; S317-S319 VanDerWaalsContact O-N 3.14Å; S319-D321 PolarHBondContact O-N 3.49Å
320	E	40.4	Very low	45.2	Very low	189 Å²	189	150.6 Å²	150.6	88%	0.883	82%	0.82	S	S	*	*			trans	-77.3	102.9	154.5	-77.4	170.9	88.2	0	0	106.8	V318	V318-E320 PolarHBondContact O-N 3.23Å
321	D	46.9	Very low	44.5	Very low	233 Å²	233	152.7 Å²	152.7	100%	1.246	82%	0.824	S	S	*	*			trans	-149.3	0	153.6	-134	-63.8	0	0	0	107.4	S319	S319-D321 PolarHBondContact O-N 3.49Å

Retrieved 321 of 321 residues in 193.4 ms (Link to these results)

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