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Beta-2 adrenergic receptor

G protein-coupled receptor for catecholamines that couples to both G(s) and G(i) proteins, activating bifurcated signaling pathways. ADRB2 binds epinephrine (Epi) with an approximately 30-fold greater affinity than norepinephrine (NE). In the heart, Epi- and NE-activated ADRB2 induces rapid and slow cardiomyocyte contraction rate, respectively. Both NE and Epi promote coupling to G(s)/PKA pathway to regulate myocyte contraction rate. Epi also promotes ADRB2 coupling to G(i) proteins to exert cardioprotective effects especially in the conditions of hypoxia and oxidative stress through the G(i)/PI3K/Akt signaling pathway. ADRB2-G(s) signaling delivers proapoptotic signals in cardiomyocytes although G(i)-mediated survival effect appears to predominate. ADRB2 also transduces signals independently of PKA to regulate cellular pH by modulating Na(+)/H(+) exchanger SLC9A3 function.

AlphaFold DB (P07550), UniProt , Accession X5DQM5, Species HUMAN (Homo sapiens, Human), Gene ADRB2, Length 413 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	41.1	Very low	44.7	Very low	257 Å²	257	140.7 Å²	140.7	100%	1.266	87%	0.872	S	S	*	*				0	115.9	0	-76.7	170.8	172.1	0	0	107.3
2	G	44.9	Very low	45.1	Very low	83 Å²	83	141.9 Å²	141.9	86%	0.856	87%	0.867	S	S	*	*			trans	115.3	71.7	173.4	0	0	0	0	0	117.2
3	Q	44.3	Very low	45.1	Very low	189 Å²	189	138.5 Å²	138.5	88%	0.883	86%	0.862	S	S	*	*			trans	-112.3	162.5	143.5	-98.7	-162	-5	0	0	106
4	P	51.9	Low	45.6	Very low	124 Å²	124	137.6 Å²	137.6	81%	0.805	86%	0.86	S	S	*	*			cis	-147.7	-172.7	33.8	36.8	-13.5	0	0	0	115.1
5	G	45.7	Very low	45.4	Very low	69 Å²	69	139.7 Å²	139.7	71%	0.711	86%	0.862	S	S	*	*			trans	146.8	98.8	147	0	0	0	0	0	118.6
6	N	46.6	Very low	45.3	Very low	170 Å²	170	135.1 Å²	135.1	91%	0.909	85%	0.85	S	S	*	*			trans	64.9	119.7	146.8	-77.9	-2.2	0	0	0	122.1
7	G	40.4	Very low	45.2	Very low	74 Å²	74	134.5 Å²	134.5	76%	0.763	85%	0.852	S	S	*	*			trans	-76.6	159.7	167.5	0	0	0	0	0	114.1
8	S	50.2	Low	45.5	Very low	119 Å²	119	136.3 Å²	136.3	83%	0.832	85%	0.848	S	S	*	*			trans	-143.2	117.7	159.4	-70.1	0	0	0	0	106.2	F10	S8-F10 PolarHBondContact O-N 3.43Å
9	A	41.3	Very low	46	Very low	102 Å²	102	134.7 Å²	134.7	84%	0.843	85%	0.849	S	S	*	*			trans	-69.2	124.4	176.2	0	0	0	0	0	109.6
10	F	45.3	Very low	46.2	Very low	192 Å²	192	131.5 Å²	131.5	84%	0.842	83%	0.829	S	S	*	*			trans	-111.4	106.5	164	-123.4	-90.3	0	0	0	107.2	S8 L12	S8-F10 PolarHBondContact O-N 3.43Å; F10-L12 PolarHBondContact O-N 3.21Å
11	L	40.5	Very low	46.8	Very low	169 Å²	169	130.9 Å²	130.9	89%	0.885	82%	0.82	S	S	*	*			trans	-74.5	116.6	168	-71	169	0	0	0	108.2
12	L	48.7	Very low	47.7	Very low	155 Å²	155	126.4 Å²	126.4	81%	0.812	80%	0.796	S	S	*	*			trans	-113.8	115.4	158.1	-71.8	175.6	0	0	0	107.3	F10	F10-L12 PolarHBondContact O-N 3.21Å
13	A	45.8	Very low	48.7	Very low	97 Å²	97	128.7 Å²	128.7	80%	0.802	79%	0.789	S	S	*	*	P	Polyproline II helix	trans	-63.1	144	172.8	0	0	0	0	0	110.4
14	P	51	Low	49.7	Very low	127 Å²	127	123.7 Å²	123.7	83%	0.825	77%	0.771	S	S	*	*	P	Polyproline II helix	trans	-79.9	135.9	-172.3	31.7	-32.6	0	0	0	112.1
15	N	43.2	Very low	50.7	Low	169 Å²	169	121.4 Å²	121.4	90%	0.904	75%	0.754	S	S	*	*	P	Polyproline II helix	trans	-62.4	146.6	164	-112.2	-15.1	0	0	0	111.6
16	G	43.6	Very low	52	Low	65 Å²	65	123.5 Å²	123.5	67%	0.67	75%	0.746	S	S	*	*			trans	82.7	91.8	148	0	0	0	0	0	116.7	H18	G16-H18 VanDerWaalsContact C-N 3.27Å; G16-H18 PolarHBondContact O-N 2.78Å
17	S	43.8	Very low	53.1	Low	126 Å²	126	121.6 Å²	121.6	88%	0.881	73%	0.731	S	S	*	*			trans	-67.3	87	158.4	49.3	0	0	0	0	109.8	A19	S17-A19 PolarHBondContact O-N 3.35Å
18	H	51.5	Low	54.7	Low	166 Å²	166	126.7 Å²	126.7	77%	0.769	73%	0.728	S	S	*	*			trans	-64.6	113.8	155.1	-101.1	-72.9	0	0	0	107.8	G16 P20	G16-H18 VanDerWaalsContact C-N 3.27Å; G16-H18 PolarHBondContact O-N 2.78Å; H18-P20 VanDerWaalsContact C-CD 3.47Å; H18-P20 HydrophobicContact CB-CG 3.91Å; H18-P20 WeakPolarHBondContact O-CD 3.11Å
19	A	55.3	Low	56.3	Low	106 Å²	106	125 Å²	125	88%	0.876	71%	0.709	S	S	*	*			trans	-106.3	94.1	153.5	0	0	0	0	0	106.4	S17	S17-A19 PolarHBondContact O-N 3.35Å
20	P	48.1	Very low	58.6	Low	70 Å²	70	125.3 Å²	125.3	46%	0.455	69%	0.693	S	S	.	*			trans	-125.7	142.3	-174.8	37.8	-20.5	0	0	0	114.1	H18 H22	H18-P20 VanDerWaalsContact C-CD 3.47Å; H18-P20 HydrophobicContact CB-CG 3.91Å; H18-P20 WeakPolarHBondContact O-CD 3.11Å; P20-H22 PolarHBondContact O-N 3.06Å
21	D	59.4	Low	60.8	Low	120 Å²	120	120.9 Å²	120.9	64%	0.642	68%	0.682	S	S	*	*	S	Bend	trans	80.1	-36	152.2	-56	-24.7	0	0	0	121.7	D23 T25	D21-D23 PolarHBondContact O-N 3.15Å; D21-T25 WeakPolarHBondContact O-CG2 2.98Å; D21-T25 PolarHBondContact O-N 3.33Å; D21-T25 PolarHBondContact O-OG1 3.5Å
22	H	60.6	Low	63.3	Low	162 Å²	162	118.7 Å²	118.7	75%	0.75	66%	0.662	S	S	*	*	H	α-helix	trans	-65.6	-46.8	-173.3	-95.3	-63.3	0	0	0	114.4	P20 V24 T25 Q26	P20-H22 PolarHBondContact O-N 3.06Å; H22-V24 VanDerWaalsContact C-N 3.33Å; H22-V24 PolarHBondContact O-N 3.13Å; H22-T25 PolarHBondContact O-N 3.02Å; H22-T25 PolarHBondContact O-OG1 3.19Å; H22-Q26 PolarHBondContact O-N 3.4Å
23	D	65.7	Low	65.5	Low	132 Å²	132	113.6 Å²	113.6	71%	0.706	64%	0.637	S	S	*	*	H	α-helix	trans	-64.7	-39.4	-176.5	-149.1	11.6	0	0	0	111.6	D21 T25 Q26 E27	D21-D23 PolarHBondContact O-N 3.15Å; D23-T25 PolarHBondContact O-N 2.83Å; D23-Q26 PolarHBondContact O-N 3.03Å; D23-E27 WeakPolarHBondContact O-CB 3.46Å; D23-E27 PolarHBondContact O-N 3.1Å
24	V	66	Low	67.9	Low	84 Å²	84	113.4 Å²	113.4	51%	0.509	63%	0.625	S	S	.	*	H	α-helix	trans	-68	-35.5	180	-178.6	0	0	0	0	112	H22 R28	H22-V24 VanDerWaalsContact C-N 3.33Å; H22-V24 PolarHBondContact O-N 3.13Å; V24-R28 VanDerWaalsContact O-CB 3.29Å; V24-R28 WeakPolarHBondContact O-CB 3.42Å; V24-R28 PolarHBondContact O-N 3.16Å; V24-R28 VanDerWaalsContact O-N 3.14Å
25	T	72.1	Confident	70	Confident	75 Å²	75	109 Å²	109	46%	0.46	60%	0.603	S	S	.	*	H	α-helix	trans	-70.8	-40.8	177.4	55.8	0	0	0	0	112.4	D21 H22 D23 R28 D29	D21-T25 WeakPolarHBondContact O-CG2 2.98Å; D21-T25 PolarHBondContact O-N 3.33Å; D21-T25 PolarHBondContact O-OG1 3.5Å; H22-T25 PolarHBondContact O-N 3.02Å; H22-T25 PolarHBondContact O-OG1 3.19Å; D23-T25 PolarHBondContact O-N 2.83Å; T25-R28 PolarHBondContact O-N 2.84Å; T25-D29 WeakPolarHBondContact O-CB 3.15Å; T25-D29 PolarHBondContact O-N 3.34Å
26	Q	72.7	Confident	72.5	Confident	114 Å²	114	104.1 Å²	104.1	53%	0.533	58%	0.576	S	S	.	*	H	α-helix	trans	-67.8	-45.1	178.4	-174.2	177.3	-27.3	0	0	111.5	H22 D23 R28 D29 E30	H22-Q26 PolarHBondContact O-N 3.4Å; D23-Q26 PolarHBondContact O-N 3.03Å; Q26-R28 VanDerWaalsContact C-N 3.33Å; Q26-R28 PolarHBondContact O-N 3.47Å; Q26-D29 PolarHBondContact O-N 3.25Å; Q26-E30 PolarHBondContact NE2-OE1 3.11Å; Q26-E30 VanDerWaalsContact NE2-OE1 3.15Å; Q26-E30 WeakPolarHBondContact O-CG 3.27Å; Q26-E30 PolarHBondContact O-N 3.48Å
27	E	70.5	Confident	75	Confident	129 Å²	129	101.7 Å²	101.7	60%	0.603	55%	0.551	S	S	*	*	H	α-helix	trans	-61.6	-41.8	177.2	-169.4	-175.9	178.7	0	0	111.5	D23 D29 E30 V31	D23-E27 WeakPolarHBondContact O-CB 3.46Å; D23-E27 PolarHBondContact O-N 3.1Å; E27-D29 VanDerWaalsContact C-N 3.33Å; E27-D29 PolarHBondContact O-N 2.9Å; E27-E30 PolarHBondContact O-N 3.48Å; E27-V31 VanDerWaalsContact O-CG2 3.3Å; E27-V31 WeakPolarHBondContact O-CG2 3.26Å; E27-V31 PolarHBondContact O-N 3.45Å
28	R	72.6	Confident	77.6	Confident	181 Å²	181	100.4 Å²	100.4	68%	0.683	53%	0.533	S	S	*	.	H	α-helix	trans	-62.4	-40.8	176.3	-175.1	-177.4	-66.1	-169.8	0.9	112	V24 T25 Q26 W32	V24-R28 VanDerWaalsContact O-CB 3.29Å; V24-R28 WeakPolarHBondContact O-CB 3.42Å; V24-R28 PolarHBondContact O-N 3.16Å; V24-R28 VanDerWaalsContact O-N 3.14Å; T25-R28 PolarHBondContact O-N 2.84Å; Q26-R28 VanDerWaalsContact C-N 3.33Å; Q26-R28 PolarHBondContact O-N 3.47Å; R28-W32 WeakPolarHBondContact O-CB 3.47Å; R28-W32 PolarHBondContact O-N 2.84Å
29	D	84.2	Confident	79.7	Confident	83 Å²	83	96 Å²	96	44%	0.444	52%	0.518	S	S	.	.	H	α-helix	trans	-66.2	-42.7	177.9	-85.2	2.9	0	0	0	111.3	T25 Q26 E27 W32 V33	T25-D29 WeakPolarHBondContact O-CB 3.15Å; T25-D29 PolarHBondContact O-N 3.34Å; Q26-D29 PolarHBondContact O-N 3.25Å; E27-D29 VanDerWaalsContact C-N 3.33Å; E27-D29 PolarHBondContact O-N 2.9Å; D29-W32 PolarHBondContact O-N 2.84Å; D29-V33 WeakPolarHBondContact O-CB 3.06Å; D29-V33 VanDerWaalsContact O-CG2 3.25Å; D29-V33 WeakPolarHBondContact O-CG2 3.32Å; D29-V33 PolarHBondContact O-N 3.37Å
30	E	89.4	Confident	81.7	Confident	110 Å²	110	91.7 Å²	91.7	51%	0.514	48%	0.48	S	S	.	.	H	α-helix	trans	-63.6	-46.1	177	-72.7	-179.4	-162.6	0	0	111.9	Q26 E27 W32 V33 V34	Q26-E30 PolarHBondContact NE2-OE1 3.11Å; Q26-E30 VanDerWaalsContact NE2-OE1 3.15Å; Q26-E30 WeakPolarHBondContact O-CG 3.27Å; Q26-E30 PolarHBondContact O-N 3.48Å; E27-E30 PolarHBondContact O-N 3.48Å; E30-W32 VanDerWaalsContact C-N 3.3Å; E30-W32 PolarHBondContact O-N 3.3Å; E30-V33 PolarHBondContact O-N 3.17Å; E30-V34 WeakPolarHBondContact O-CG2 2.99Å; E30-V34 PolarHBondContact O-N 3.25Å
31	V	92.9	Very high	84.1	Confident	98 Å²	98	91.6 Å²	91.6	59%	0.594	48%	0.48	S	S	*	.	H	α-helix	trans	-61	-40	176	173.4	0	0	0	0	111.2	E27 G35	E27-V31 VanDerWaalsContact O-CG2 3.3Å; E27-V31 WeakPolarHBondContact O-CG2 3.26Å; E27-V31 PolarHBondContact O-N 3.45Å; V31-G35 PolarHBondContact O-N 3.02Å
32	W	93.2	Very high	85.9	Confident	124 Å²	124	91 Å²	91	47%	0.47	48%	0.477	S	S	.	.	H	α-helix	trans	-65.1	-44.7	176.4	-175.5	90.4	0	0	0	112	R28 D29 E30 G35 M36 I94	R28-W32 WeakPolarHBondContact O-CB 3.47Å; R28-W32 PolarHBondContact O-N 2.84Å; D29-W32 PolarHBondContact O-N 2.84Å; E30-W32 VanDerWaalsContact C-N 3.3Å; E30-W32 PolarHBondContact O-N 3.3Å; W32-G35 PolarHBondContact O-N 3.02Å; W32-M36 HydrophobicContact CD2-CG 4Å; W32-M36 HydrophobicContact CE3-CG 4.29Å; W32-M36 HydrophobicContact CH2-CG 4.09Å; W32-M36 HydrophobicContact CZ2-CE 3.81Å; W32-M36 HydrophobicContact CZ2-CG 3.78Å; W32-M36 HydrophobicContact CZ3-CG 4.33Å; W32-M36 WeakPolarHBondContact O-CB 3.41Å; W32-M36 WeakPolarHBondContact O-CG 3.23Å; W32-M36 PolarHBondContact O-N 3.45Å; W32-I94 HydrophobicContact CH2-CG2 4.41Å
33	V	94.1	Very high	87.6	Confident	48 Å²	48	85 Å²	85	29%	0.291	45%	0.45	S	S	.	.	H	α-helix	trans	-62.2	-47.5	177.9	169.4	0	0	0	0	110.8	D29 E30 M36 G37 L95	D29-V33 WeakPolarHBondContact O-CB 3.06Å; D29-V33 VanDerWaalsContact O-CG2 3.25Å; D29-V33 WeakPolarHBondContact O-CG2 3.32Å; D29-V33 PolarHBondContact O-N 3.37Å; E30-V33 PolarHBondContact O-N 3.17Å; V33-M36 PolarHBondContact O-N 3.07Å; V33-G37 PolarHBondContact O-N 3.21Å; V33-L95 HydrophobicContact CG1-CD2 4.13Å; V33-L95 WeakPolarHBondContact O-CD2 3.37Å
34	V	95.3	Very high	89.2	Confident	92 Å²	92	80 Å²	80	56%	0.558	42%	0.424	S	S	*	.	H	α-helix	trans	-62.7	-46.3	177.8	173.8	0	0	0	0	110.6	E30 G37 I38	E30-V34 WeakPolarHBondContact O-CG2 2.99Å; E30-V34 PolarHBondContact O-N 3.25Å; V34-G37 PolarHBondContact O-N 3.47Å; V34-I38 HydrophobicContact CG1-CD1 4.06Å; V34-I38 WeakPolarHBondContact O-CG1 3.4Å; V34-I38 PolarHBondContact O-N 3.37Å
35	G	96.1	Very high	90.7	Very high	34 Å²	34	81.4 Å²	81.4	35%	0.351	43%	0.428	S	S	.	.	H	α-helix	trans	-59.2	-48.1	177.7	0	0	0	0	0	112.7	V31 W32 I38 V39	V31-G35 PolarHBondContact O-N 3.02Å; W32-G35 PolarHBondContact O-N 3.02Å; G35-I38 PolarHBondContact O-N 3.04Å; G35-V39 WeakPolarHBondContact O-CG2 3.24Å; G35-V39 PolarHBondContact O-N 3.42Å
36	M	95.1	Very high	91.9	Very high	67 Å²	67	80.5 Å²	80.5	33%	0.33	43%	0.428	S	S	.	.	H	α-helix	trans	-65	-39.6	176.7	-77.4	-60.1	-170.5	0	0	112.2	W32 V33 I38 V39 M40 L95	W32-M36 HydrophobicContact CD2-CG 4Å; W32-M36 HydrophobicContact CE3-CG 4.29Å; W32-M36 HydrophobicContact CH2-CG 4.09Å; W32-M36 HydrophobicContact CZ2-CE 3.81Å; W32-M36 HydrophobicContact CZ2-CG 3.78Å; W32-M36 HydrophobicContact CZ3-CG 4.33Å; W32-M36 WeakPolarHBondContact O-CB 3.41Å; W32-M36 WeakPolarHBondContact O-CG 3.23Å; W32-M36 PolarHBondContact O-N 3.45Å; V33-M36 PolarHBondContact O-N 3.07Å; M36-I38 VanDerWaalsContact C-N 3.33Å; M36-I38 PolarHBondContact O-N 3.34Å; M36-V39 PolarHBondContact O-N 2.95Å; M36-M40 WeakPolarHBondContact O-CB 3.42Å; M36-M40 VanDerWaalsContact O-CG 3.26Å; M36-M40 WeakPolarHBondContact O-CG 3.44Å; M36-M40 PolarHBondContact O-N 3.37Å; M36-L95 HydrophobicContact CB-CD2 3.94Å
37	G	96.8	Very high	93.2	Very high	15 Å²	15	75.1 Å²	75.1	16%	0.155	40%	0.403	C	S	.	.	H	α-helix	trans	-59.1	-42.3	175.5	0	0	0	0	0	112.7	V33 V34 S41	V33-G37 PolarHBondContact O-N 3.21Å; V34-G37 PolarHBondContact O-N 3.47Å; G37-S41 VanDerWaalsContact O-CB 3.26Å; G37-S41 WeakPolarHBondContact O-CB 3.41Å; G37-S41 PolarHBondContact O-N 2.89Å; G37-S41 PolarHBondContact O-OG 3.3Å
38	I	97.2	Very high	94.5	Very high	98 Å²	98	70.5 Å²	70.5	50%	0.503	38%	0.383	S	S	.	.	H	α-helix	trans	-64.4	-48.8	174.8	-65.9	166.6	0	0	0	110.6	V34 G35 M36 M40 S41 L42	V34-I38 HydrophobicContact CG1-CD1 4.06Å; V34-I38 WeakPolarHBondContact O-CG1 3.4Å; V34-I38 PolarHBondContact O-N 3.37Å; G35-I38 PolarHBondContact O-N 3.04Å; M36-I38 VanDerWaalsContact C-N 3.33Å; M36-I38 PolarHBondContact O-N 3.34Å; I38-M40 PolarHBondContact O-N 2.87Å; I38-S41 PolarHBondContact O-N 2.63Å; I38-L42 HydrophobicContact CG2-CD1 4.11Å; I38-L42 HydrophobicContact CG2-CG 4.48Å; I38-L42 WeakPolarHBondContact O-CG 3.3Å; I38-L42 PolarHBondContact O-N 3.03Å
39	V	97.1	Very high	95.7	Very high	75 Å²	75	67.8 Å²	67.8	46%	0.455	38%	0.377	S	S	.	.	H	α-helix	trans	-59.7	-48.1	-179.7	171.4	0	0	0	0	111.3	G35 M36 S41 L42 I43	G35-V39 WeakPolarHBondContact O-CG2 3.24Å; G35-V39 PolarHBondContact O-N 3.42Å; M36-V39 PolarHBondContact O-N 2.95Å; V39-S41 PolarHBondContact O-N 3.08Å; V39-L42 PolarHBondContact O-N 3.41Å; V39-I43 HydrophobicContact CG1-CD1 4.02Å; V39-I43 WeakPolarHBondContact O-CG1 3.41Å; V39-I43 PolarHBondContact O-N 3.36Å
40	M	97	Very high	96.4	Very high	15 Å²	15	64.1 Å²	64.1	7%	0.074	36%	0.359	C	S	.	.	H	α-helix	trans	-64.1	-39.4	178.5	-68.6	179	171.3	0	0	111.9	M36 I38 L42 I43 V44 A91 I94 L95 W313	M36-M40 WeakPolarHBondContact O-CB 3.42Å; M36-M40 VanDerWaalsContact O-CG 3.26Å; M36-M40 WeakPolarHBondContact O-CG 3.44Å; M36-M40 PolarHBondContact O-N 3.37Å; I38-M40 PolarHBondContact O-N 2.87Å; M40-L42 PolarHBondContact O-N 2.92Å; M40-I43 WeakPolarHBondContact O-CB 3.5Å; M40-I43 PolarHBondContact O-N 3.43Å; M40-V44 WeakPolarHBondContact O-CG2 3.33Å; M40-V44 PolarHBondContact O-N 3.4Å; M40-A91 HydrophobicContact CB-CB 3.99Å; M40-A91 HydrophobicContact CG-CB 4.35Å; M40-A91 HydrophobicContact SD-CB 3.62Å; M40-I94 HydrophobicContact CE-CB 4.31Å; M40-I94 HydrophobicContact CE-CD1 3.97Å; M40-I94 HydrophobicContact CE-CG2 4.06Å; M40-L95 HydrophobicContact SD-CD1 4.49Å; M40-L95 HydrophobicContact SD-CG 4.38Å; M40-W313 HydrophobicContact CB-CH2 4.18Å; M40-W313 HydrophobicContact CB-CZ3 4.24Å; M40-W313 HydrophobicContact CE-CD2 4.36Å; M40-W313 HydrophobicContact CE-CE3 4.39Å; M40-W313 HydrophobicContact CE-CH2 3.63Å; M40-W313 HydrophobicContact CE-CZ2 3.59Å; M40-W313 HydrophobicContact CE-CZ3 4.05Å; M40-W313 HydrophobicContact CG-CH2 3.61Å; M40-W313 HydrophobicContact CG-CZ3 3.64Å; M40-W313 HydrophobicContact SD-CH2 3.51Å; M40-W313 VanDerWaalsContact SD-CH2 3.51Å; M40-W313 HydrophobicContact SD-CZ2 3.92Å; M40-W313 HydrophobicContact SD-CZ3 4.13Å
41	S	97.4	Very high	96.8	Very high	67 Å²	67	58.9 Å²	58.9	47%	0.469	34%	0.335	S	S	.	.	H	α-helix	trans	-63.2	-41.1	175.5	-61.1	0	0	0	0	112	G37 I38 V39 V44 L45	G37-S41 VanDerWaalsContact O-CB 3.26Å; G37-S41 WeakPolarHBondContact O-CB 3.41Å; G37-S41 PolarHBondContact O-N 2.89Å; G37-S41 PolarHBondContact O-OG 3.3Å; I38-S41 PolarHBondContact O-N 2.63Å; V39-S41 PolarHBondContact O-N 3.08Å; S41-V44 PolarHBondContact O-N 3.1Å; S41-L45 VanDerWaalsContact O-CG 3.31Å; S41-L45 WeakPolarHBondContact O-CG 3.46Å; S41-L45 PolarHBondContact O-N 3.08Å
42	L	97.7	Very high	97.1	Very high	108 Å²	108	57.2 Å²	57.2	57%	0.565	33%	0.325	S	S	*	.	H	α-helix	trans	-65	-38.1	175.1	-70.2	174.3	0	0	0	112.1	I38 V39 M40 L45 A46	I38-L42 HydrophobicContact CG2-CD1 4.11Å; I38-L42 HydrophobicContact CG2-CG 4.48Å; I38-L42 WeakPolarHBondContact O-CG 3.3Å; I38-L42 PolarHBondContact O-N 3.03Å; V39-L42 PolarHBondContact O-N 3.41Å; M40-L42 PolarHBondContact O-N 2.92Å; L42-L45 PolarHBondContact O-N 3.08Å; L42-A46 VanDerWaalsContact O-CB 3.31Å; L42-A46 WeakPolarHBondContact O-CB 3.49Å; L42-A46 PolarHBondContact O-N 2.98Å
43	I	97.5	Very high	97.3	Very high	36 Å²	36	52.4 Å²	52.4	19%	0.185	31%	0.308	C	S	.	.	H	α-helix	trans	-60.8	-50.2	174.2	-69.5	164.7	0	0	0	110.1	V39 M40 L45 A46 I47 V87 V317	V39-I43 HydrophobicContact CG1-CD1 4.02Å; V39-I43 WeakPolarHBondContact O-CG1 3.41Å; V39-I43 PolarHBondContact O-N 3.36Å; M40-I43 WeakPolarHBondContact O-CB 3.5Å; M40-I43 PolarHBondContact O-N 3.43Å; I43-L45 PolarHBondContact O-N 3.41Å; I43-A46 PolarHBondContact O-N 3.43Å; I43-I47 HydrophobicContact CG2-CD1 3.67Å; I43-I47 HydrophobicContact CG2-CG1 4.39Å; I43-I47 VanDerWaalsContact O-CG1 3.27Å; I43-I47 WeakPolarHBondContact O-CG1 3.49Å; I43-I47 PolarHBondContact O-N 3Å; I43-V87 HydrophobicContact CG2-CG1 4.44Å; I43-V317 HydrophobicContact CD1-CG2 3.91Å; I43-V317 HydrophobicContact CG1-CG2 4.39Å; I43-V317 HydrophobicContact CG2-CG2 4.21Å
44	V	98.3	Very high	97.5	Very high	27 Å²	27	50.1 Å²	50.1	16%	0.164	29%	0.294	C	S	.	.	H	α-helix	trans	-56.5	-50	177.2	169	0	0	0	0	110.9	M40 S41 A46 I47 V48 V87 P88	M40-V44 WeakPolarHBondContact O-CG2 3.33Å; M40-V44 PolarHBondContact O-N 3.4Å; S41-V44 PolarHBondContact O-N 3.1Å; V44-A46 VanDerWaalsContact C-N 3.34Å; V44-A46 PolarHBondContact O-N 3.25Å; V44-I47 PolarHBondContact O-N 2.86Å; V44-V48 HydrophobicContact CG1-CG2 4.31Å; V44-V48 WeakPolarHBondContact O-CG2 3.37Å; V44-V48 PolarHBondContact O-N 3.41Å; V44-V87 HydrophobicContact CG2-CB 4.08Å; V44-V87 HydrophobicContact CG2-CG1 3.59Å; V44-P88 HydrophobicContact CG1-CG 4.06Å; V44-P88 HydrophobicContact CG2-CG 3.99Å
45	L	98	Very high	97.6	Very high	114 Å²	114	47.7 Å²	47.7	60%	0.597	28%	0.277	S	S	*	.	H	α-helix	trans	-59.7	-43.2	179.1	-72.6	171.7	0	0	0	112	S41 L42 I43 F49	S41-L45 VanDerWaalsContact O-CG 3.31Å; S41-L45 WeakPolarHBondContact O-CG 3.46Å; S41-L45 PolarHBondContact O-N 3.08Å; L42-L45 PolarHBondContact O-N 3.08Å; I43-L45 PolarHBondContact O-N 3.41Å; L45-F49 WeakPolarHBondContact O-CB 3.49Å; L45-F49 PolarHBondContact O-N 3Å
46	A	97.7	Very high	97.7	Very high	55 Å²	55	48.9 Å²	48.9	46%	0.455	28%	0.278	S	S	.	.	H	α-helix	trans	-63.4	-43.7	178.5	0	0	0	0	0	112.2	L42 I43 V44 G50	L42-A46 VanDerWaalsContact O-CB 3.31Å; L42-A46 WeakPolarHBondContact O-CB 3.49Å; L42-A46 PolarHBondContact O-N 2.98Å; I43-A46 PolarHBondContact O-N 3.43Å; V44-A46 VanDerWaalsContact C-N 3.34Å; V44-A46 PolarHBondContact O-N 3.25Å; A46-G50 PolarHBondContact O-N 3.06Å
47	I	98.4	Very high	97.8	Very high	1 Å²	1	45.7 Å²	45.7	1%	0.005	26%	0.262	C	S	.	.	H	α-helix	trans	-62.7	-53.8	177.4	-65.6	166.3	0	0	0	110.1	I43 V44 N51 D79 V87	I43-I47 HydrophobicContact CG2-CD1 3.67Å; I43-I47 HydrophobicContact CG2-CG1 4.39Å; I43-I47 VanDerWaalsContact O-CG1 3.27Å; I43-I47 WeakPolarHBondContact O-CG1 3.49Å; I43-I47 PolarHBondContact O-N 3Å; V44-I47 PolarHBondContact O-N 2.86Å; I47-N51 WeakPolarHBondContact O-CB 3.43Å; I47-N51 PolarHBondContact O-N 3.43Å; I47-N51 PolarHBondContact O-ND2 3.43Å; I47-D79 WeakPolarHBondContact CG2-O 3.29Å; I47-V87 HydrophobicContact CD1-CG2 4.15Å
48	V	98.6	Very high	97.8	Very high	32 Å²	32	45.2 Å²	45.2	19%	0.194	26%	0.256	C	S	.	.	H	α-helix	trans	-63.6	-52	-175.3	174.1	0	0	0	0	110.5	V44 G50 N51 V52 L80 L84	V44-V48 HydrophobicContact CG1-CG2 4.31Å; V44-V48 WeakPolarHBondContact O-CG2 3.37Å; V44-V48 PolarHBondContact O-N 3.41Å; V48-G50 PolarHBondContact O-N 3.01Å; V48-N51 PolarHBondContact O-N 3.08Å; V48-V52 HydrophobicContact CG1-CG2 4.41Å; V48-V52 WeakPolarHBondContact O-CB 3.26Å; V48-V52 WeakPolarHBondContact O-CG2 3.47Å; V48-V52 PolarHBondContact O-N 2.98Å; V48-L80 HydrophobicContact CB-CD1 4.36Å; V48-L80 HydrophobicContact CG1-CD1 4.02Å; V48-L80 HydrophobicContact CG2-CD1 4.43Å; V48-L84 HydrophobicContact CG1-CD2 4.05Å; V48-L84 HydrophobicContact CG2-CD2 3.67Å; V48-L84 HydrophobicContact CG2-CG 4.03Å
49	F	98	Very high	97.8	Very high	124 Å²	124	43.7 Å²	43.7	54%	0.544	26%	0.258	S	S	.	.	H	α-helix	trans	-60.7	-47.8	-178.9	176.8	-98.3	0	0	0	112.1	L45 N51 L53 L340	L45-F49 WeakPolarHBondContact O-CB 3.49Å; L45-F49 PolarHBondContact O-N 3Å; F49-N51 PolarHBondContact O-N 3.35Å; F49-L53 WeakPolarHBondContact O-CB 3.26Å; F49-L53 PolarHBondContact O-N 3.28Å; F49-L340 HydrophobicContact CE2-CD2 4.33Å; F49-L340 HydrophobicContact CZ-CD2 3.65Å
50	G	97.9	Very high	97.8	Very high	7 Å²	7	46.8 Å²	46.8	7%	0.072	27%	0.265	C	S	.	.	H	α-helix	trans	-63.5	-43.9	-177.2	0	0	0	0	0	112.6	A46 V48 L53 V54 P323	A46-G50 PolarHBondContact O-N 3.06Å; V48-G50 PolarHBondContact O-N 3.01Å; G50-L53 WeakPolarHBondContact O-CB 3.47Å; G50-L53 PolarHBondContact O-N 3.18Å; G50-V54 WeakPolarHBondContact O-CG2 3.38Å; G50-V54 PolarHBondContact O-N 3.28Å; G50-V54 VanDerWaalsContact O-N 3.08Å; G50-P323 WeakPolarHBondContact O-CG 3.08Å
51	N	98.4	Very high	97.7	Very high	0 Å²	0	47.1 Å²	47.1	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-75.1	-34.9	-178.7	-71.3	-65.6	0	0	0	112.7	I47 V48 F49 L53 V54 I55 A76 D79 L80 S319	I47-N51 WeakPolarHBondContact O-CB 3.43Å; I47-N51 PolarHBondContact O-N 3.43Å; I47-N51 PolarHBondContact O-ND2 3.43Å; V48-N51 PolarHBondContact O-N 3.08Å; F49-N51 PolarHBondContact O-N 3.35Å; N51-L53 VanDerWaalsContact C-N 3.27Å; N51-L53 PolarHBondContact O-N 3.02Å; N51-V54 PolarHBondContact O-N 3Å; N51-I55 VanDerWaalsContact O-CG1 3.31Å; N51-I55 WeakPolarHBondContact O-CG1 3.47Å; N51-I55 PolarHBondContact O-N 3.43Å; N51-A76 HydrophobicContact CB-CB 4.38Å; N51-D79 WeakPolarHBondContact ND2-CB 3.25Å; N51-L80 HydrophobicContact CB-CB 4.15Å; N51-S319 PolarHBondContact ND2-O 3.47Å
52	V	98.4	Very high	97.6	Very high	63 Å²	63	51 Å²	51	38%	0.382	28%	0.277	S	S	.	.	H	α-helix	trans	-58.7	-42	168.6	169.7	0	0	0	0	110.6	V48 I55 T56 L80	V48-V52 HydrophobicContact CG1-CG2 4.41Å; V48-V52 WeakPolarHBondContact O-CB 3.26Å; V48-V52 WeakPolarHBondContact O-CG2 3.47Å; V48-V52 PolarHBondContact O-N 2.98Å; V52-I55 PolarHBondContact O-N 3.44Å; V52-T56 VanDerWaalsContact O-CB 3.26Å; V52-T56 WeakPolarHBondContact O-CB 3.47Å; V52-T56 PolarHBondContact O-N 3.3Å; V52-T56 PolarHBondContact O-OG1 2.93Å; V52-L80 HydrophobicContact CG2-CD1 3.87Å; V52-L80 HydrophobicContact CG2-CD2 4.19Å
53	L	97.7	Very high	97.3	Very high	22 Å²	22	51.3 Å²	51.3	12%	0.115	27%	0.271	C	S	.	.	H	α-helix	trans	-64.4	-40.8	178.6	-168.6	69.5	0	0	0	112.2	F49 G50 N51 A57 F336 L339 L340	F49-L53 WeakPolarHBondContact O-CB 3.26Å; F49-L53 PolarHBondContact O-N 3.28Å; G50-L53 WeakPolarHBondContact O-CB 3.47Å; G50-L53 PolarHBondContact O-N 3.18Å; N51-L53 VanDerWaalsContact C-N 3.27Å; N51-L53 PolarHBondContact O-N 3.02Å; L53-A57 VanDerWaalsContact O-CB 3.25Å; L53-A57 WeakPolarHBondContact O-CB 3.34Å; L53-A57 PolarHBondContact O-N 3.24Å; L53-F336 HydrophobicContact CD1-CD1 4.32Å; L53-F336 HydrophobicContact CD2-CB 4.05Å; L53-F336 HydrophobicContact CD2-CD1 3.63Å; L53-F336 HydrophobicContact CD2-CD2 4.21Å; L53-F336 HydrophobicContact CD2-CE1 4.05Å; L53-F336 HydrophobicContact CD2-CG 3.71Å; L53-F336 HydrophobicContact CG-CD1 3.55Å; L53-F336 HydrophobicContact CG-CE1 3.8Å; L53-F336 HydrophobicContact CG-CG 4.17Å; L53-L339 HydrophobicContact CD1-CB 3.84Å; L53-L339 HydrophobicContact CD1-CD1 3.78Å; L53-L339 HydrophobicContact CD1-CG 4.48Å; L53-L340 HydrophobicContact CD1-CD2 4.08Å; L53-L340 HydrophobicContact CD1-CG 4.29Å; L53-L340 HydrophobicContact CD2-CD1 4.23Å; L53-L340 HydrophobicContact CD2-CG 4.5Å
54	V	98.1	Very high	97.2	Very high	0 Å²	0	49.8 Å²	49.8	0%	0	26%	0.263	C	S	.	.	H	α-helix	trans	-61.6	-52	175.3	171.8	0	0	0	0	111.1	G50 N51 T56 A57 I58 I72 A76 P323 Y326 F332 F336	G50-V54 WeakPolarHBondContact O-CG2 3.38Å; G50-V54 PolarHBondContact O-N 3.28Å; G50-V54 VanDerWaalsContact O-N 3.08Å; N51-V54 PolarHBondContact O-N 3Å; V54-T56 VanDerWaalsContact C-N 3.35Å; V54-T56 PolarHBondContact O-N 3.33Å; V54-A57 PolarHBondContact O-N 2.89Å; V54-I58 HydrophobicContact CG1-CD1 3.91Å; V54-I58 WeakPolarHBondContact O-CG1 3.5Å; V54-I58 PolarHBondContact O-N 3.04Å; V54-I72 HydrophobicContact CG1-CG2 3.88Å; V54-A76 HydrophobicContact CB-CB 4.26Å; V54-A76 HydrophobicContact CG1-CB 3.88Å; V54-P323 HydrophobicContact CG2-CB 4.15Å; V54-P323 HydrophobicContact CG2-CG 4.15Å; V54-Y326 HydrophobicContact CG1-CD2 4.28Å; V54-Y326 HydrophobicContact CG1-CE2 4.16Å; V54-Y326 HydrophobicContact CG2-CD2 3.6Å; V54-Y326 HydrophobicContact CG2-CE2 4.03Å; V54-F332 HydrophobicContact CG1-CE1 4.37Å; V54-F336 HydrophobicContact CG2-CE1 4.49Å; V54-F336 HydrophobicContact CG2-CZ 3.95Å
55	I	98.3	Very high	97	Very high	42 Å²	42	51.2 Å²	51.2	22%	0.215	27%	0.268	C	S	.	.	H	α-helix	trans	-59.6	-47.9	179.7	-65.5	165.4	0	0	0	110	N51 V52 A57 I58 A59 T73 A76 L80	N51-I55 VanDerWaalsContact O-CG1 3.31Å; N51-I55 WeakPolarHBondContact O-CG1 3.47Å; N51-I55 PolarHBondContact O-N 3.43Å; V52-I55 PolarHBondContact O-N 3.44Å; I55-A57 VanDerWaalsContact C-N 3.35Å; I55-A57 PolarHBondContact O-N 2.86Å; I55-I58 PolarHBondContact O-N 3.1Å; I55-A59 WeakPolarHBondContact O-CB 3.44Å; I55-A59 PolarHBondContact O-N 3.18Å; I55-T73 HydrophobicContact CG1-CG2 4.36Å; I55-A76 HydrophobicContact CD1-CB 4.24Å; I55-A76 HydrophobicContact CG1-CB 3.82Å; I55-L80 HydrophobicContact CD1-CD2 3.9Å
56	T	97.8	Very high	96.8	Very high	59 Å²	59	48.7 Å²	48.7	36%	0.362	26%	0.257	S	S	.	.	H	α-helix	trans	-61.6	-41.3	179.2	-54.3	0	0	0	0	111.9	V52 V54 A59 K60 L339	V52-T56 VanDerWaalsContact O-CB 3.26Å; V52-T56 WeakPolarHBondContact O-CB 3.47Å; V52-T56 PolarHBondContact O-N 3.3Å; V52-T56 PolarHBondContact O-OG1 2.93Å; V54-T56 VanDerWaalsContact C-N 3.35Å; V54-T56 PolarHBondContact O-N 3.33Å; T56-A59 PolarHBondContact O-N 3.35Å; T56-K60 VanDerWaalsContact O-CB 3.24Å; T56-K60 WeakPolarHBondContact O-CB 3.49Å; T56-K60 PolarHBondContact O-N 3.04Å; T56-L339 HydrophobicContact CG2-CD1 4.07Å; T56-L339 HydrophobicContact CG2-CD2 3.89Å
57	A	97.3	Very high	96.6	Very high	0 Å²	0	46.9 Å²	46.9	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-62.8	-45.7	177.8	0	0	0	0	0	112	L53 V54 I55 F61 L64 A335 F336 L339	L53-A57 VanDerWaalsContact O-CB 3.25Å; L53-A57 WeakPolarHBondContact O-CB 3.34Å; L53-A57 PolarHBondContact O-N 3.24Å; V54-A57 PolarHBondContact O-N 2.89Å; I55-A57 VanDerWaalsContact C-N 3.35Å; I55-A57 PolarHBondContact O-N 2.86Å; A57-F61 HydrophobicContact CB-CD2 4.46Å; A57-F61 WeakPolarHBondContact O-CB 3.38Å; A57-F61 VanDerWaalsContact O-CD2 3.27Å; A57-F61 WeakPolarHBondContact O-CD2 3.49Å; A57-F61 PolarHBondContact O-N 3.12Å; A57-L64 HydrophobicContact CB-CD1 4.15Å; A57-A335 HydrophobicContact CB-CB 4.01Å; A57-F336 HydrophobicContact CB-CD1 4.06Å; A57-F336 HydrophobicContact CB-CE1 3.78Å; A57-L339 HydrophobicContact CB-CD1 3.83Å
58	I	97.4	Very high	96.3	Very high	5 Å²	5	47.6 Å²	47.6	3%	0.026	25%	0.245	C	C	.	.	H	α-helix	trans	-68.7	-38.4	-179.8	-63	165.6	0	0	0	110.7	V54 I55 Q65 N69 I72 T73 F332	V54-I58 HydrophobicContact CG1-CD1 3.91Å; V54-I58 WeakPolarHBondContact O-CG1 3.5Å; V54-I58 PolarHBondContact O-N 3.04Å; I55-I58 PolarHBondContact O-N 3.1Å; I58-Q65 VanDerWaalsContact O-CG 3.24Å; I58-Q65 WeakPolarHBondContact O-CG 3.42Å; I58-N69 HydrophobicContact CD1-CB 4.21Å; I58-N69 HydrophobicContact CG1-CB 4.36Å; I58-N69 HydrophobicContact CG2-CB 4.22Å; I58-I72 HydrophobicContact CD1-CB 4.4Å; I58-I72 HydrophobicContact CD1-CG2 3.87Å; I58-T73 VanDerWaalsContact CD1-OG1 3.3Å; I58-T73 WeakPolarHBondContact CD1-OG1 3.48Å; I58-F332 HydrophobicContact CD1-CE1 4.04Å; I58-F332 HydrophobicContact CD1-CZ 3.92Å; I58-F332 HydrophobicContact CG1-CE1 3.83Å; I58-F332 HydrophobicContact CG1-CZ 3.91Å
59	A	97	Very high	96.1	Very high	66 Å²	66	47 Å²	47	55%	0.545	24%	0.241	S	C	.	.	H	α-helix	trans	-65.7	-44.4	177.6	0	0	0	0	0	112.3	I55 T56 Q65	I55-A59 WeakPolarHBondContact O-CB 3.44Å; I55-A59 PolarHBondContact O-N 3.18Å; T56-A59 PolarHBondContact O-N 3.35Å; A59-Q65 PolarHBondContact O-NE2 3.27Å
60	K	96.6	Very high	96.1	Very high	139 Å²	139	43 Å²	43	60%	0.604	22%	0.222	S	C	*	.	H	α-helix	trans	-81.2	-35.3	-172.6	-169	175.3	-176.1	175.6	0	114.1	T56 L339	T56-K60 VanDerWaalsContact O-CB 3.24Å; T56-K60 WeakPolarHBondContact O-CB 3.49Å; T56-K60 PolarHBondContact O-N 3.04Å; K60-L339 HydrophobicContact CD-CD2 3.74Å
61	F	96	Very high	96.1	Very high	23 Å²	23	42.8 Å²	42.8	10%	0.101	22%	0.219	C	C	.	.			trans	-101.3	108.4	-174.8	-64.4	-77.1	0	0	0	111.4	A57 R63 L64 A335 E338 L339	A57-F61 HydrophobicContact CB-CD2 4.46Å; A57-F61 WeakPolarHBondContact O-CB 3.38Å; A57-F61 VanDerWaalsContact O-CD2 3.27Å; A57-F61 WeakPolarHBondContact O-CD2 3.49Å; A57-F61 PolarHBondContact O-N 3.12Å; F61-R63 HydrophobicContact CB-CG 4.26Å; F61-R63 PolarHBondContact O-N 2.87Å; F61-L64 HydrophobicContact CB-CB 4.41Å; F61-L64 HydrophobicContact CB-CD1 4.13Å; F61-L64 HydrophobicContact CB-CG 4.17Å; F61-L64 HydrophobicContact CD2-CD1 4.47Å; F61-L64 WeakPolarHBondContact O-CA 3.43Å; F61-L64 WeakPolarHBondContact O-CB 3.22Å; F61-L64 PolarHBondContact O-N 3.39Å; F61-A335 HydrophobicContact CD2-CB 3.43Å; F61-A335 VanDerWaalsContact CD2-CB 3.43Å; F61-A335 HydrophobicContact CE2-CB 3.47Å; F61-A335 VanDerWaalsContact CE2-CB 3.47Å; F61-A335 HydrophobicContact CG-CB 4.19Å; F61-A335 HydrophobicContact CZ-CB 4.23Å; F61-E338 VanDerWaalsContact CE1-CD 3.47Å; F61-E338 HydrophobicContact CE1-CG 4.35Å; F61-E338 WeakPolarHBondContact CE1-OE1 3.48Å; F61-E338 HydrophobicContact CZ-CB 3.91Å; F61-E338 HydrophobicContact CZ-CG 3.95Å; F61-L339 HydrophobicContact CE2-CD1 4.29Å; F61-L339 HydrophobicContact CE2-CD2 4.33Å; F61-L339 HydrophobicContact CE2-CG 3.99Å
62	E	93.9	Very high	96	Very high	149 Å²	149	43 Å²	43	70%	0.696	22%	0.221	S	C	*	.	G	3₁₀ helix	trans	-54.1	-38.5	-179.8	-175.5	171.7	-162.3	0	0	113.4	L64 Q65	E62-L64 PolarHBondContact O-N 3.36Å; E62-Q65 WeakPolarHBondContact O-CB 3.46Å; E62-Q65 PolarHBondContact O-N 3.48Å
63	R	92.9	Very high	96	Very high	113 Å²	113	41.6 Å²	41.6	43%	0.426	21%	0.212	S	C	.	.	G	3₁₀ helix	trans	-57.3	-21.5	174.7	70.2	174.8	-177.7	-177.3	-5.5	114.3	F61 D331 I334	F61-R63 HydrophobicContact CB-CG 4.26Å; F61-R63 PolarHBondContact O-N 2.87Å; R63-D331 PolarHBondContact NH2-O 3.1Å; R63-D331 VanDerWaalsContact NH2-O 3.12Å; R63-I334 VanDerWaalsContact NH2-CB 3.34Å
64	L	94.3	Very high	96	Very high	4 Å²	4	40.8 Å²	40.8	2%	0.021	21%	0.208	C	C	.	.	G	3₁₀ helix	trans	-95.1	-5.2	177.5	-66.1	-179.6	0	0	0	112.2	A57 F61 E62 T66 N69 D331 F332 A335	A57-L64 HydrophobicContact CB-CD1 4.15Å; F61-L64 HydrophobicContact CB-CB 4.41Å; F61-L64 HydrophobicContact CB-CD1 4.13Å; F61-L64 HydrophobicContact CB-CG 4.17Å; F61-L64 HydrophobicContact CD2-CD1 4.47Å; F61-L64 WeakPolarHBondContact O-CA 3.43Å; F61-L64 WeakPolarHBondContact O-CB 3.22Å; F61-L64 PolarHBondContact O-N 3.39Å; E62-L64 PolarHBondContact O-N 3.36Å; L64-T66 PolarHBondContact O-N 3.34Å; L64-N69 WeakPolarHBondContact O-CB 3.36Å; L64-N69 PolarHBondContact O-ND2 3.32Å; L64-D331 HydrophobicContact CD2-CB 3.71Å; L64-F332 HydrophobicContact CD1-CD1 4.31Å; L64-F332 HydrophobicContact CD1-CE1 4.36Å; L64-F332 HydrophobicContact CD2-CD2 4.35Å; L64-F332 HydrophobicContact CD2-CE2 4.35Å; L64-A335 HydrophobicContact CD1-CB 3.81Å
65	Q	94.9	Very high	96	Very high	57 Å²	57	40.8 Å²	40.8	27%	0.266	21%	0.209	S	C	.	.			trans	-82.1	56	-179	-63.1	-177.1	-2.5	0	0	112.2	I58 A59 E62 Y70 K147	I58-Q65 VanDerWaalsContact O-CG 3.24Å; I58-Q65 WeakPolarHBondContact O-CG 3.42Å; A59-Q65 PolarHBondContact O-NE2 3.27Å; E62-Q65 WeakPolarHBondContact O-CB 3.46Å; E62-Q65 PolarHBondContact O-N 3.48Å; Q65-Y70 HydrophobicContact CB-CE2 4.41Å; Q65-K147 WeakPolarHBondContact O-CE 3.24Å; Q65-K147 PolarHBondContact O-NZ 3.05Å
66	T	92.8	Very high	96	Very high	61 Å²	61	38.8 Å²	38.8	37%	0.374	20%	0.198	S	C	.	.			trans	-93.3	161.3	175.4	68.9	0	0	0	0	111.1	L64 T68 N69 Y70	L64-T66 PolarHBondContact O-N 3.34Å; T66-T68 PolarHBondContact O-N 3.44Å; T66-N69 PolarHBondContact O-N 3.19Å; T66-N69 VanDerWaalsContact O-N 3.09Å; T66-N69 WeakPolarHBondContact OG1-CB 3.44Å; T66-N69 VanDerWaalsContact OG1-CG 3.24Å; T66-N69 PolarHBondContact OG1-N 2.99Å; T66-N69 PolarHBondContact OG1-ND2 2.99Å; T66-Y70 PolarHBondContact O-N 3.33Å
67	V	93.2	Very high	96.1	Very high	18 Å²	18	38.2 Å²	38.2	11%	0.109	20%	0.196	C	C	.	.	H	α-helix	trans	-58.1	-45.9	179.2	173.7	0	0	0	0	112.2	N69 Y70 F71 L145 K147 A150	V67-N69 PolarHBondContact O-N 3.49Å; V67-Y70 WeakPolarHBondContact O-CB 3.24Å; V67-Y70 PolarHBondContact O-N 2.93Å; V67-Y70 VanDerWaalsContact O-N 3.07Å; V67-F71 HydrophobicContact CG1-CD2 4.48Å; V67-F71 HydrophobicContact CG1-CE2 3.83Å; V67-F71 HydrophobicContact CG1-CZ 4.46Å; V67-F71 PolarHBondContact O-N 3.17Å; V67-L145 HydrophobicContact CG1-CD2 3.42Å; V67-L145 VanDerWaalsContact CG1-CD2 3.42Å; V67-L145 HydrophobicContact CG1-CG 3.83Å; V67-K147 HydrophobicContact CG2-CG 4.46Å; V67-A150 HydrophobicContact CG1-CB 3.8Å
68	T	92.8	Very high	96.1	Very high	16 Å²	16	38.2 Å²	38.2	10%	0.098	20%	0.196	C	C	.	.	H	α-helix	trans	-59.4	-38.2	176	-51.3	0	0	0	0	111.8	T66 Y70 F71 I72 D130 R131 L275	T66-T68 PolarHBondContact O-N 3.44Å; T68-Y70 VanDerWaalsContact C-N 3.31Å; T68-Y70 PolarHBondContact O-N 2.92Å; T68-F71 PolarHBondContact O-N 3.16Å; T68-I72 HydrophobicContact CG2-CD1 4.4Å; T68-I72 PolarHBondContact O-N 3.49Å; T68-D130 PolarHBondContact OG1-OD2 3.39Å; T68-R131 PolarHBondContact OG1-NE 2.96Å; T68-R131 PolarHBondContact OG1-NH2 2.96Å; T68-L275 HydrophobicContact CG2-CD1 4.18Å
69	N	95.1	Very high	96.2	Very high	18 Å²	18	38 Å²	38	10%	0.096	20%	0.195	C	C	.	.	H	α-helix	trans	-72.2	-24.8	179.1	-69.6	-11.2	0	0	0	112.3	I58 L64 T66 V67 F71 I72 T73	I58-N69 HydrophobicContact CD1-CB 4.21Å; I58-N69 HydrophobicContact CG1-CB 4.36Å; I58-N69 HydrophobicContact CG2-CB 4.22Å; L64-N69 WeakPolarHBondContact O-CB 3.36Å; L64-N69 PolarHBondContact O-ND2 3.32Å; T66-N69 PolarHBondContact O-N 3.19Å; T66-N69 VanDerWaalsContact O-N 3.09Å; T66-N69 WeakPolarHBondContact OG1-CB 3.44Å; T66-N69 VanDerWaalsContact OG1-CG 3.24Å; T66-N69 PolarHBondContact OG1-N 2.99Å; T66-N69 PolarHBondContact OG1-ND2 2.99Å; V67-N69 PolarHBondContact O-N 3.49Å; N69-F71 VanDerWaalsContact C-N 3.34Å; N69-I72 PolarHBondContact O-N 2.9Å; N69-I72 WeakPolarHBondContact OD1-CD1 3.45Å; N69-T73 PolarHBondContact O-N 2.91Å; N69-T73 PolarHBondContact O-OG1 3.43Å
70	Y	97	Very high	96.3	Very high	40 Å²	40	36.4 Å²	36.4	16%	0.157	18%	0.177	C	C	.	.	H	α-helix	trans	-64.3	-39.4	169.4	-80.7	-159.8	0	0	0	111.6	Q65 T66 V67 T68 T73 S74 K147 R151 I154	Q65-Y70 HydrophobicContact CB-CE2 4.41Å; T66-Y70 PolarHBondContact O-N 3.33Å; V67-Y70 WeakPolarHBondContact O-CB 3.24Å; V67-Y70 PolarHBondContact O-N 2.93Å; V67-Y70 VanDerWaalsContact O-N 3.07Å; T68-Y70 VanDerWaalsContact C-N 3.31Å; T68-Y70 PolarHBondContact O-N 2.92Å; Y70-T73 WeakPolarHBondContact O-CB 3.4Å; Y70-T73 PolarHBondContact O-N 3.07Å; Y70-S74 PolarHBondContact O-N 3.02Å; Y70-K147 HydrophobicContact CE1-CB 4.04Å; Y70-K147 HydrophobicContact CE1-CG 4.43Å; Y70-R151 HydrophobicContact CD1-CG 4.11Å; Y70-R151 HydrophobicContact CE1-CG 4.06Å; Y70-R151 PolarHBondContact OH-NH2 3.07Å; Y70-I154 WeakPolarHBondContact O-CD1 3.25Å
71	F	97.5	Very high	96.3	Very high	3 Å²	3	32.1 Å²	32.1	1%	0.013	16%	0.163	C	C	.	.	H	α-helix	trans	-68.1	-37.8	172.6	-60.2	-56	0	0	0	112.1	V67 T68 N69 T73 S74 L75 T123 V126 I127 D130 L145 A150 I153 I154	V67-F71 HydrophobicContact CG1-CD2 4.48Å; V67-F71 HydrophobicContact CG1-CE2 3.83Å; V67-F71 HydrophobicContact CG1-CZ 4.46Å; V67-F71 PolarHBondContact O-N 3.17Å; T68-F71 PolarHBondContact O-N 3.16Å; N69-F71 VanDerWaalsContact C-N 3.34Å; F71-T73 VanDerWaalsContact C-N 3.29Å; F71-T73 PolarHBondContact O-N 3.08Å; F71-S74 WeakPolarHBondContact O-CB 3.4Å; F71-S74 PolarHBondContact O-N 3.39Å; F71-S74 VanDerWaalsContact O-N 3.13Å; F71-L75 PolarHBondContact O-N 3.39Å; F71-T123 HydrophobicContact CB-CG2 4.19Å; F71-T123 VanDerWaalsContact O-CG2 3.23Å; F71-T123 WeakPolarHBondContact O-CG2 3.45Å; F71-V126 HydrophobicContact CD1-CG1 3.82Å; F71-V126 HydrophobicContact CD2-CG1 4.39Å; F71-V126 HydrophobicContact CE1-CG1 3.42Å; F71-V126 VanDerWaalsContact CE1-CG1 3.42Å; F71-V126 HydrophobicContact CE2-CG1 4.04Å; F71-V126 HydrophobicContact CG-CG1 4.3Å; F71-V126 HydrophobicContact CZ-CG1 3.55Å; F71-I127 HydrophobicContact CB-CD1 3.85Å; F71-I127 HydrophobicContact CB-CG1 3.47Å; F71-I127 VanDerWaalsContact CB-CG1 3.47Å; F71-I127 HydrophobicContact CD2-CG1 4.33Å; F71-I127 HydrophobicContact CG-CG1 4.15Å; F71-D130 HydrophobicContact CE2-CB 4.09Å; F71-L145 HydrophobicContact CE2-CD2 4.26Å; F71-A150 HydrophobicContact CE1-CB 4.49Å; F71-A150 HydrophobicContact CZ-CB 4.11Å; F71-I153 HydrophobicContact CE1-CB 4.3Å; F71-I153 HydrophobicContact CE1-CG2 4Å; F71-I153 HydrophobicContact CZ-CG2 4.42Å; F71-I154 HydrophobicContact CD1-CD1 3.97Å; F71-I154 HydrophobicContact CD1-CG1 3.63Å; F71-I154 HydrophobicContact CE1-CD1 4.29Å; F71-I154 HydrophobicContact CE1-CG1 3.82Å
72	I	97	Very high	96.5	Very high	5 Å²	5	31.2 Å²	31.2	3%	0.026	16%	0.158	C	C	.	.	H	α-helix	trans	-60.7	-39.2	171.6	-72	167.4	0	0	0	111.3	V54 I58 T68 N69 S74 L75 A76 L275 Y326 F332	V54-I72 HydrophobicContact CG1-CG2 3.88Å; I58-I72 HydrophobicContact CD1-CB 4.4Å; I58-I72 HydrophobicContact CD1-CG2 3.87Å; T68-I72 HydrophobicContact CG2-CD1 4.4Å; T68-I72 PolarHBondContact O-N 3.49Å; N69-I72 PolarHBondContact O-N 2.9Å; N69-I72 WeakPolarHBondContact OD1-CD1 3.45Å; I72-S74 VanDerWaalsContact C-N 3.35Å; I72-L75 PolarHBondContact O-N 3.12Å; I72-A76 WeakPolarHBondContact O-CB 3.44Å; I72-A76 PolarHBondContact O-N 3.49Å; I72-L275 HydrophobicContact CD1-CD2 4.32Å; I72-Y326 HydrophobicContact CD1-CE1 3.78Å; I72-Y326 HydrophobicContact CG1-CE1 4.05Å; I72-Y326 HydrophobicContact CG2-CE1 3.88Å; I72-Y326 HydrophobicContact CG2-CE2 3.83Å; I72-Y326 VanDerWaalsContact CG2-CZ 3.43Å; I72-Y326 WeakPolarHBondContact CG2-OH 3.08Å; I72-F332 HydrophobicContact CG2-CZ 4.45Å
73	T	98	Very high	96.7	Very high	33 Å²	33	24.1 Å²	24.1	20%	0.202	13%	0.125	C	C	.	.	H	α-helix	trans	-62.2	-42.1	172.9	-58	0	0	0	0	111.3	I55 I58 N69 Y70 F71 L75 A76 C77	I55-T73 HydrophobicContact CG1-CG2 4.36Å; I58-T73 VanDerWaalsContact CD1-OG1 3.3Å; I58-T73 WeakPolarHBondContact CD1-OG1 3.48Å; N69-T73 PolarHBondContact O-N 2.91Å; N69-T73 PolarHBondContact O-OG1 3.43Å; Y70-T73 WeakPolarHBondContact O-CB 3.4Å; Y70-T73 PolarHBondContact O-N 3.07Å; F71-T73 VanDerWaalsContact C-N 3.29Å; F71-T73 PolarHBondContact O-N 3.08Å; T73-L75 VanDerWaalsContact C-N 3.33Å; T73-L75 PolarHBondContact O-N 3.49Å; T73-A76 PolarHBondContact O-N 3.48Å; T73-C77 PolarHBondContact O-N 3.03Å; T73-C77 PolarHBondContact O-SG 3.18Å
74	S	98.4	Very high	96.9	Very high	5 Å²	5	23.5 Å²	23.5	4%	0.035	13%	0.13	C	C	.	.	H	α-helix	trans	-57.8	-45.9	174.4	-174.6	0	0	0	0	111.8	Y70 F71 I72 C77 A78 T123 W158	Y70-S74 PolarHBondContact O-N 3.02Å; F71-S74 WeakPolarHBondContact O-CB 3.4Å; F71-S74 PolarHBondContact O-N 3.39Å; F71-S74 VanDerWaalsContact O-N 3.13Å; I72-S74 VanDerWaalsContact C-N 3.35Å; S74-C77 WeakPolarHBondContact O-CB 3.47Å; S74-C77 PolarHBondContact O-N 3.09Å; S74-A78 PolarHBondContact O-N 3.26Å; S74-A78 VanDerWaalsContact O-N 3.1Å; S74-T123 PolarHBondContact OG-OG1 2.91Å; S74-W158 PolarHBondContact OG-NE1 3Å
75	L	98.3	Very high	97.1	Very high	1 Å²	1	24.2 Å²	24.2	1%	0.005	14%	0.137	C	C	.	.	H	α-helix	trans	-61.8	-46	176	-177.1	62.1	0	0	0	111.7	F71 I72 T73 C77 A78 D79 T123 L124 I278	F71-L75 PolarHBondContact O-N 3.39Å; I72-L75 PolarHBondContact O-N 3.12Å; T73-L75 VanDerWaalsContact C-N 3.33Å; T73-L75 PolarHBondContact O-N 3.49Å; L75-C77 VanDerWaalsContact C-N 3.28Å; L75-C77 PolarHBondContact O-N 2.87Å; L75-A78 PolarHBondContact O-N 2.82Å; L75-A78 VanDerWaalsContact O-N 3.16Å; L75-D79 PolarHBondContact O-N 2.89Å; L75-T123 HydrophobicContact CB-CG2 4.1Å; L75-L124 HydrophobicContact CD2-CD2 3.84Å; L75-L124 HydrophobicContact CD2-CG 4.47Å; L75-I278 HydrophobicContact CD2-CG2 4.18Å
76	A	98.5	Very high	97.3	Very high	0 Å²	0	21.5 Å²	21.5	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-63.5	-32	177.3	0	0	0	0	0	112.7	N51 V54 I55 I72 T73 L80	N51-A76 HydrophobicContact CB-CB 4.38Å; V54-A76 HydrophobicContact CB-CB 4.26Å; V54-A76 HydrophobicContact CG1-CB 3.88Å; I55-A76 HydrophobicContact CD1-CB 4.24Å; I55-A76 HydrophobicContact CG1-CB 3.82Å; I72-A76 WeakPolarHBondContact O-CB 3.44Å; I72-A76 PolarHBondContact O-N 3.49Å; T73-A76 PolarHBondContact O-N 3.48Å; A76-L80 WeakPolarHBondContact O-CB 3.33Å; A76-L80 PolarHBondContact O-N 3.33Å
77	C	98.6	Very high	97.5	Very high	46 Å²	46	18.6 Å²	18.6	31%	0.311	11%	0.106	S	C	.	.	H	α-helix	trans	-66.9	-44.3	172.3	-72.1	0	0	0	0	111.7	T73 S74 L75 L80 V81 W158	T73-C77 PolarHBondContact O-N 3.03Å; T73-C77 PolarHBondContact O-SG 3.18Å; S74-C77 WeakPolarHBondContact O-CB 3.47Å; S74-C77 PolarHBondContact O-N 3.09Å; L75-C77 VanDerWaalsContact C-N 3.28Å; L75-C77 PolarHBondContact O-N 2.87Å; C77-L80 PolarHBondContact O-N 2.93Å; C77-V81 VanDerWaalsContact O-CG2 3.31Å; C77-V81 WeakPolarHBondContact O-CG2 3.42Å; C77-V81 PolarHBondContact O-N 2.85Å; C77-W158 HydrophobicContact CB-CH2 4.46Å; C77-W158 HydrophobicContact CB-CZ2 4.01Å
78	A	98.6	Very high	97.8	Very high	0 Å²	0	19.9 Å²	19.9	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-60.6	-46.2	175.2	0	0	0	0	0	111.2	S74 L75 L80 V81 M82 S120 W158	S74-A78 PolarHBondContact O-N 3.26Å; S74-A78 VanDerWaalsContact O-N 3.1Å; L75-A78 PolarHBondContact O-N 2.82Å; L75-A78 VanDerWaalsContact O-N 3.16Å; A78-L80 VanDerWaalsContact C-N 3.34Å; A78-L80 PolarHBondContact O-N 3.06Å; A78-V81 PolarHBondContact O-N 3.02Å; A78-M82 WeakPolarHBondContact O-CG 3.4Å; A78-M82 PolarHBondContact O-N 2.93Å; A78-S120 WeakPolarHBondContact CB-OG 3.49Å; A78-W158 HydrophobicContact CB-CH2 4.14Å; A78-W158 HydrophobicContact CB-CZ2 4.22Å
79	D	98.6	Very high	98	Very high	2 Å²	2	21.4 Å²	21.4	1%	0.011	12%	0.12	C	C	.	.	H	α-helix	trans	-63.9	-35.9	176.3	-71.4	-35.3	0	0	0	112.8	I47 N51 L75 M82 G83 S319 N322	I47-D79 WeakPolarHBondContact CG2-O 3.29Å; N51-D79 WeakPolarHBondContact ND2-CB 3.25Å; L75-D79 PolarHBondContact O-N 2.89Å; D79-M82 WeakPolarHBondContact O-CB 3.48Å; D79-M82 PolarHBondContact O-N 2.9Å; D79-G83 PolarHBondContact O-N 3.47Å; D79-S319 VanDerWaalsContact OD1-CA 3.3Å; D79-S319 WeakPolarHBondContact OD1-CA 3.32Å; D79-S319 WeakPolarHBondContact OD1-CB 3.16Å; D79-S319 PolarHBondContact OD1-OG 3.22Å; D79-N322 PolarHBondContact OD2-ND2 3.48Å
80	L	98.6	Very high	98.1	Very high	32 Å²	32	20.7 Å²	20.7	17%	0.168	12%	0.117	C	C	.	.	H	α-helix	trans	-68	-42.6	175.6	-179.1	60.9	0	0	0	111.6	V48 N51 V52 I55 A76 C77 A78 M82 G83 L84	V48-L80 HydrophobicContact CB-CD1 4.36Å; V48-L80 HydrophobicContact CG1-CD1 4.02Å; V48-L80 HydrophobicContact CG2-CD1 4.43Å; N51-L80 HydrophobicContact CB-CB 4.15Å; V52-L80 HydrophobicContact CG2-CD1 3.87Å; V52-L80 HydrophobicContact CG2-CD2 4.19Å; I55-L80 HydrophobicContact CD1-CD2 3.9Å; A76-L80 WeakPolarHBondContact O-CB 3.33Å; A76-L80 PolarHBondContact O-N 3.33Å; C77-L80 PolarHBondContact O-N 2.93Å; A78-L80 VanDerWaalsContact C-N 3.34Å; A78-L80 PolarHBondContact O-N 3.06Å; L80-M82 VanDerWaalsContact C-N 3.32Å; L80-G83 PolarHBondContact O-N 2.94Å; L80-L84 HydrophobicContact CD1-CD1 3.88Å; L80-L84 HydrophobicContact CD1-CG 4.14Å; L80-L84 HydrophobicContact CG-CD1 3.95Å; L80-L84 WeakPolarHBondContact O-CG 3.36Å; L80-L84 PolarHBondContact O-N 3.13Å
81	V	98.6	Very high	98.1	Very high	49 Å²	49	19.3 Å²	19.3	30%	0.297	11%	0.114	S	C	.	.	H	α-helix	trans	-63.3	-40.4	174.7	175.9	0	0	0	0	110.2	C77 A78 G83 L84 A85 I112 C116	C77-V81 VanDerWaalsContact O-CG2 3.31Å; C77-V81 WeakPolarHBondContact O-CG2 3.42Å; C77-V81 PolarHBondContact O-N 2.85Å; A78-V81 PolarHBondContact O-N 3.02Å; V81-G83 PolarHBondContact O-N 3.03Å; V81-L84 PolarHBondContact O-N 3.47Å; V81-A85 HydrophobicContact CG1-CB 4.26Å; V81-A85 WeakPolarHBondContact O-CA 3.42Å; V81-A85 WeakPolarHBondContact O-CB 3.27Å; V81-A85 PolarHBondContact O-N 3.33Å; V81-I112 HydrophobicContact CG1-CG2 3.58Å; V81-C116 WeakPolarHBondContact CG1-SG 3.47Å
82	M	98.4	Very high	98.1	Very high	3 Å²	3	20.1 Å²	20.1	2%	0.015	12%	0.121	C	C	.	.	I	π-helix	trans	-55.7	-50.6	171.2	-72.1	-69.7	-81.1	0	0	111.9	A78 D79 L80 L84 V86 V87 C116 V117 W286 Y316	A78-M82 WeakPolarHBondContact O-CG 3.4Å; A78-M82 PolarHBondContact O-N 2.93Å; D79-M82 WeakPolarHBondContact O-CB 3.48Å; D79-M82 PolarHBondContact O-N 2.9Å; L80-M82 VanDerWaalsContact C-N 3.32Å; M82-L84 VanDerWaalsContact C-N 3.3Å; M82-L84 PolarHBondContact O-N 3.34Å; M82-V86 HydrophobicContact CE-CG1 4.23Å; M82-V86 WeakPolarHBondContact O-CA 3.49Å; M82-V86 WeakPolarHBondContact O-CB 3.25Å; M82-V86 PolarHBondContact O-N 2.99Å; M82-V86 HydrophobicContact SD-CB 3.9Å; M82-V86 HydrophobicContact SD-CG1 4.07Å; M82-V86 HydrophobicContact SD-CG2 3.71Å; M82-V87 WeakPolarHBondContact O-CG2 3.45Å; M82-V87 PolarHBondContact O-N 2.84Å; M82-C116 HydrophobicContact CG-CB 3.36Å; M82-C116 HydrophobicContact SD-CB 3.31Å; M82-C116 WeakPolarHBondContact SD-CB 3.28Å; M82-V117 HydrophobicContact CE-CG2 4.17Å; M82-W286 HydrophobicContact CE-CZ2 4.34Å; M82-Y316 HydrophobicContact CE-CD1 3.27Å; M82-Y316 HydrophobicContact CE-CE1 3.51Å; M82-Y316 HydrophobicContact CE-CG 4.3Å
83	G	98.1	Very high	98.1	Very high	0 Å²	0	21.4 Å²	21.4	0%	0	13%	0.127	C	C	.	.	I	π-helix	trans	-65	-28.5	-178.3	0	0	0	0	0	114.5	D79 L80 V81 P88	D79-G83 PolarHBondContact O-N 3.47Å; L80-G83 PolarHBondContact O-N 2.94Å; V81-G83 PolarHBondContact O-N 3.03Å; G83-P88 VanDerWaalsContact O-CD 3.26Å; G83-P88 WeakPolarHBondContact O-CD 3.34Å; G83-P88 VanDerWaalsContact O-CG 3.23Å; G83-P88 WeakPolarHBondContact O-CG 3.41Å
84	L	98.4	Very high	98	Very high	101 Å²	101	21.6 Å²	21.6	53%	0.529	13%	0.126	S	C	.	.	I	π-helix	trans	-95.1	-40.5	-178.5	-68.2	174.4	0	0	0	113.5	V48 L80 V81 M82	V48-L84 HydrophobicContact CG1-CD2 4.05Å; V48-L84 HydrophobicContact CG2-CD2 3.67Å; V48-L84 HydrophobicContact CG2-CG 4.03Å; L80-L84 HydrophobicContact CD1-CD1 3.88Å; L80-L84 HydrophobicContact CD1-CG 4.14Å; L80-L84 HydrophobicContact CG-CD1 3.95Å; L80-L84 WeakPolarHBondContact O-CG 3.36Å; L80-L84 PolarHBondContact O-N 3.13Å; V81-L84 PolarHBondContact O-N 3.47Å; M82-L84 VanDerWaalsContact C-N 3.3Å; M82-L84 PolarHBondContact O-N 3.34Å
85	A	98.1	Very high	97.8	Very high	19 Å²	19	23.6 Å²	23.6	16%	0.157	14%	0.136	C	C	.	.	I	π-helix	trans	-111.4	-16.3	-167.7	0	0	0	0	0	114.1	V81 F89 W109 I112	V81-A85 HydrophobicContact CG1-CB 4.26Å; V81-A85 WeakPolarHBondContact O-CA 3.42Å; V81-A85 WeakPolarHBondContact O-CB 3.27Å; V81-A85 PolarHBondContact O-N 3.33Å; A85-F89 WeakPolarHBondContact O-CD2 3.39Å; A85-W109 VanDerWaalsContact O-CD1 3.29Å; A85-I112 HydrophobicContact CB-CD1 4.33Å; A85-I112 HydrophobicContact CB-CG2 4.19Å
86	V	98.6	Very high	97.6	Very high	0 Å²	0	28.4 Å²	28.4	0%	0	16%	0.16	C	C	.	.	I	π-helix	trans	-111.4	-62	-176.3	-179	0	0	0	0	111.1	M82 F89 G90 W109 I112 D113 Y316	M82-V86 HydrophobicContact CE-CG1 4.23Å; M82-V86 WeakPolarHBondContact O-CA 3.49Å; M82-V86 WeakPolarHBondContact O-CB 3.25Å; M82-V86 PolarHBondContact O-N 2.99Å; M82-V86 HydrophobicContact SD-CB 3.9Å; M82-V86 HydrophobicContact SD-CG1 4.07Å; M82-V86 HydrophobicContact SD-CG2 3.71Å; V86-F89 PolarHBondContact O-N 3.18Å; V86-G90 PolarHBondContact O-N 3.11Å; V86-W109 PolarHBondContact O-NE1 2.94Å; V86-I112 HydrophobicContact CG2-CB 4.33Å; V86-I112 HydrophobicContact CG2-CG2 3.65Å; V86-D113 HydrophobicContact CG1-CB 3.83Å; V86-D113 HydrophobicContact CG2-CB 4.18Å; V86-Y316 HydrophobicContact CG1-CE1 4.07Å
87	V	98.2	Very high	97.4	Very high	0 Å²	0	35.8 Å²	35.8	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-60.3	-42.3	-172.6	-177.2	0	0	0	0	113	I43 V44 I47 M82 F89 G90 A91 W313 Y316	I43-V87 HydrophobicContact CG2-CG1 4.44Å; V44-V87 HydrophobicContact CG2-CB 4.08Å; V44-V87 HydrophobicContact CG2-CG1 3.59Å; I47-V87 HydrophobicContact CD1-CG2 4.15Å; M82-V87 WeakPolarHBondContact O-CG2 3.45Å; M82-V87 PolarHBondContact O-N 2.84Å; V87-F89 PolarHBondContact O-N 3.29Å; V87-G90 PolarHBondContact O-N 3.46Å; V87-A91 WeakPolarHBondContact O-CB 3.47Å; V87-A91 PolarHBondContact O-N 3.18Å; V87-W313 HydrophobicContact CG1-CH2 4.03Å; V87-W313 HydrophobicContact CG1-CZ3 3.89Å; V87-Y316 HydrophobicContact CG2-CD2 4.32Å; V87-Y316 HydrophobicContact CG2-CG 4.18Å
88	P	98.2	Very high	97.2	Very high	44 Å²	44	37.5 Å²	37.5	29%	0.286	20%	0.196	S	C	.	.	H	α-helix	trans	-63.5	-39.6	179.5	-24.3	36.1	0	0	0	113.3	V44 G83 A91 A92	V44-P88 HydrophobicContact CG1-CG 4.06Å; V44-P88 HydrophobicContact CG2-CG 3.99Å; G83-P88 VanDerWaalsContact O-CD 3.26Å; G83-P88 WeakPolarHBondContact O-CD 3.34Å; G83-P88 VanDerWaalsContact O-CG 3.23Å; G83-P88 WeakPolarHBondContact O-CG 3.41Å; P88-A91 WeakPolarHBondContact O-CB 3.45Å; P88-A91 PolarHBondContact O-N 3.02Å; P88-A92 PolarHBondContact O-N 2.88Å
89	F	98.1	Very high	97.1	Very high	48 Å²	48	37.5 Å²	37.5	21%	0.211	20%	0.196	C	C	.	.	H	α-helix	trans	-75	-36.1	178.6	-64.1	-83.5	0	0	0	111.7	A85 V86 V87 A91 A92 H93 W99 F101 W105	A85-F89 WeakPolarHBondContact O-CD2 3.39Å; V86-F89 PolarHBondContact O-N 3.18Å; V87-F89 PolarHBondContact O-N 3.29Å; F89-A91 VanDerWaalsContact C-N 3.31Å; F89-A91 PolarHBondContact O-N 3.45Å; F89-A92 PolarHBondContact O-N 3.17Å; F89-H93 WeakPolarHBondContact O-CB 3.28Å; F89-H93 PolarHBondContact O-N 2.65Å; F89-W99 HydrophobicContact CB-CH2 4.1Å; F89-W99 HydrophobicContact CB-CZ3 4.25Å; F89-F101 HydrophobicContact CD1-CD1 4.16Å; F89-F101 AromaticContact CD1-CD2 3.99Å; F89-F101 HydrophobicContact CD1-CD2 3.99Å; F89-F101 AromaticContact CD1-CE1 3.95Å; F89-F101 HydrophobicContact CD1-CE1 3.95Å; F89-F101 AromaticContact CD1-CE2 3.78Å; F89-F101 HydrophobicContact CD1-CE2 3.78Å; F89-F101 HydrophobicContact CD1-CG 4.19Å; F89-F101 AromaticContact CD1-CZ 3.75Å; F89-F101 HydrophobicContact CD1-CZ 3.75Å; F89-F101 HydrophobicContact CE1-CD1 4.08Å; F89-F101 AromaticContact CE1-CE1 3.93Å; F89-F101 HydrophobicContact CE1-CE1 3.93Å; F89-F101 HydrophobicContact CE1-CG 4.47Å; F89-F101 HydrophobicContact CE1-CZ 4.19Å; F89-W105 AromaticContact CD1-CD1 4Å; F89-W105 AromaticContact CD1-NE1 3.36Å; F89-W105 AromaticContact CD2-NE1 3.97Å; F89-W105 HydrophobicContact CE1-CZ2 4.42Å; F89-W105 AromaticContact CE1-NE1 3.24Å; F89-W105 AromaticContact CE2-CZ2 3.85Å; F89-W105 HydrophobicContact CE2-CZ2 3.85Å; F89-W105 AromaticContact CE2-NE1 3.86Å; F89-W105 AromaticContact CG-NE1 3.73Å; F89-W105 AromaticContact CZ-CE2 3.9Å; F89-W105 AromaticContact CZ-CZ2 3.79Å; F89-W105 HydrophobicContact CZ-CZ2 3.79Å; F89-W105 AromaticContact CZ-NE1 3.5Å
90	G	97.1	Very high	97.1	Very high	4 Å²	4	40.8 Å²	40.8	4%	0.041	22%	0.217	C	C	.	.	H	α-helix	trans	-61.7	-39.4	169.7	0	0	0	0	0	112.3	V86 V87 H93 I94	V86-G90 PolarHBondContact O-N 3.11Å; V87-G90 PolarHBondContact O-N 3.46Å; G90-H93 PolarHBondContact O-N 3.49Å; G90-I94 WeakPolarHBondContact O-CG1 3.28Å; G90-I94 PolarHBondContact O-N 3.02Å; G90-I94 VanDerWaalsContact O-N 3.15Å
91	A	97.4	Very high	97	Very high	10 Å²	10	42.9 Å²	42.9	8%	0.083	23%	0.225	C	C	.	.	H	α-helix	trans	-62.3	-49.9	174.4	0	0	0	0	0	111.1	M40 V87 P88 F89 H93 I94 L95 W313	M40-A91 HydrophobicContact CB-CB 3.99Å; M40-A91 HydrophobicContact CG-CB 4.35Å; M40-A91 HydrophobicContact SD-CB 3.62Å; V87-A91 WeakPolarHBondContact O-CB 3.47Å; V87-A91 PolarHBondContact O-N 3.18Å; P88-A91 WeakPolarHBondContact O-CB 3.45Å; P88-A91 PolarHBondContact O-N 3.02Å; F89-A91 VanDerWaalsContact C-N 3.31Å; F89-A91 PolarHBondContact O-N 3.45Å; A91-H93 VanDerWaalsContact C-N 3.32Å; A91-H93 PolarHBondContact O-N 2.94Å; A91-I94 PolarHBondContact O-N 3.45Å; A91-L95 VanDerWaalsContact O-CG 3.3Å; A91-L95 WeakPolarHBondContact O-CG 3.33Å; A91-L95 PolarHBondContact O-N 3.48Å; A91-W313 HydrophobicContact CB-CH2 3.83Å; A91-W313 HydrophobicContact CB-CZ2 4.34Å
92	A	97.1	Very high	96.9	Very high	20 Å²	20	41.5 Å²	41.5	17%	0.165	22%	0.221	C	C	.	.	H	α-helix	trans	-58.6	-44.2	178.1	0	0	0	0	0	111.6	P88 F89 I94 L95 M96 F101	P88-A92 PolarHBondContact O-N 2.88Å; F89-A92 PolarHBondContact O-N 3.17Å; A92-I94 VanDerWaalsContact C-N 3.32Å; A92-I94 PolarHBondContact O-N 3.13Å; A92-L95 PolarHBondContact O-N 2.8Å; A92-M96 VanDerWaalsContact O-CB 3.25Å; A92-M96 WeakPolarHBondContact O-CB 3.42Å; A92-M96 VanDerWaalsContact O-CG 3.29Å; A92-M96 WeakPolarHBondContact O-CG 3.27Å; A92-M96 PolarHBondContact O-N 3.16Å; A92-F101 HydrophobicContact CB-CE2 4.09Å; A92-F101 HydrophobicContact CB-CZ 4.03Å
93	H	96.4	Very high	96.8	Very high	33 Å²	33	43.9 Å²	43.9	15%	0.153	23%	0.233	C	C	.	.	H	α-helix	trans	-57.3	-43.6	176.7	-176.8	-167.4	0	0	0	112	F89 G90 A91 K97 W99 D192	F89-H93 WeakPolarHBondContact O-CB 3.28Å; F89-H93 PolarHBondContact O-N 2.65Å; G90-H93 PolarHBondContact O-N 3.49Å; A91-H93 VanDerWaalsContact C-N 3.32Å; A91-H93 PolarHBondContact O-N 2.94Å; H93-K97 WeakPolarHBondContact O-CA 3.42Å; H93-K97 PolarHBondContact O-N 3.25Å; H93-K97 VanDerWaalsContact O-N 3.09Å; H93-W99 HydrophobicContact CB-CE3 4Å; H93-W99 HydrophobicContact CB-CZ3 4.27Å; H93-D192 IonicContact CE1-OD1 3.05Å
94	I	95.2	Very high	96.7	Very high	37 Å²	37	51.1 Å²	51.1	19%	0.19	27%	0.265	C	S	.	.	H	α-helix	trans	-70.4	-45.8	179.2	-69.4	174	0	0	0	111.9	W32 M40 G90 A91 A92 K97 I309 W313	W32-I94 HydrophobicContact CH2-CG2 4.41Å; M40-I94 HydrophobicContact CE-CB 4.31Å; M40-I94 HydrophobicContact CE-CD1 3.97Å; M40-I94 HydrophobicContact CE-CG2 4.06Å; G90-I94 WeakPolarHBondContact O-CG1 3.28Å; G90-I94 PolarHBondContact O-N 3.02Å; G90-I94 VanDerWaalsContact O-N 3.15Å; A91-I94 PolarHBondContact O-N 3.45Å; A92-I94 VanDerWaalsContact C-N 3.32Å; A92-I94 PolarHBondContact O-N 3.13Å; I94-K97 PolarHBondContact O-N 3.39Å; I94-I309 HydrophobicContact CD1-CG2 3.54Å; I94-I309 HydrophobicContact CG1-CG2 4.39Å; I94-W313 HydrophobicContact CD1-CZ2 3.73Å
95	L	95.1	Very high	96.7	Very high	46 Å²	46	49.4 Å²	49.4	24%	0.241	25%	0.252	C	S	.	.	H	α-helix	trans	-70.2	-38.2	-175.8	-64.7	170.1	0	0	0	112	V33 M36 M40 A91 A92 K97	V33-L95 HydrophobicContact CG1-CD2 4.13Å; V33-L95 WeakPolarHBondContact O-CD2 3.37Å; M36-L95 HydrophobicContact CB-CD2 3.94Å; M40-L95 HydrophobicContact SD-CD1 4.49Å; M40-L95 HydrophobicContact SD-CG 4.38Å; A91-L95 VanDerWaalsContact O-CG 3.3Å; A91-L95 WeakPolarHBondContact O-CG 3.33Å; A91-L95 PolarHBondContact O-N 3.48Å; A92-L95 PolarHBondContact O-N 2.8Å; L95-K97 VanDerWaalsContact C-N 3.31Å
96	M	94.3	Very high	96.7	Very high	103 Å²	103	49.1 Å²	49.1	51%	0.507	25%	0.248	S	C	.	.	H	α-helix	trans	-80.3	-13.2	177.3	-63.1	179.8	177.5	0	0	112.8	A92 M98 T100	A92-M96 VanDerWaalsContact O-CB 3.25Å; A92-M96 WeakPolarHBondContact O-CB 3.42Å; A92-M96 VanDerWaalsContact O-CG 3.29Å; A92-M96 WeakPolarHBondContact O-CG 3.27Å; A92-M96 PolarHBondContact O-N 3.16Å; M96-M98 HydrophobicContact CB-CG 4.31Å; M96-M98 PolarHBondContact O-N 2.9Å; M96-M98 VanDerWaalsContact O-N 3.08Å; M96-T100 HydrophobicContact SD-CG2 3.82Å
97	K	93.2	Very high	96.6	Very high	154 Å²	154	50.4 Å²	50.4	67%	0.67	25%	0.254	S	S	*	.	S	Bend	trans	57.9	13.4	-173.8	-55.8	178.6	-179.7	174.5	0	114.2	H93 I94 L95	H93-K97 WeakPolarHBondContact O-CA 3.42Å; H93-K97 PolarHBondContact O-N 3.25Å; H93-K97 VanDerWaalsContact O-N 3.09Å; I94-K97 PolarHBondContact O-N 3.39Å; L95-K97 VanDerWaalsContact C-N 3.31Å
98	M	94.7	Very high	96.6	Very high	82 Å²	82	53.6 Å²	53.6	40%	0.404	27%	0.268	S	S	.	.	S	Bend	trans	-153.8	158.6	178.7	66.3	-176.3	-61.3	0	0	110.3	M96 T100 T189	M96-M98 HydrophobicContact CB-CG 4.31Å; M96-M98 PolarHBondContact O-N 2.9Å; M96-M98 VanDerWaalsContact O-N 3.08Å; M98-T100 HydrophobicContact CG-CG2 4.05Å; M98-T100 HydrophobicContact SD-CG2 4.49Å; M98-T189 HydrophobicContact CE-CG2 3.39Å
99	W	97.4	Very high	96.6	Very high	0 Å²	0	52.6 Å²	52.6	0%	0	26%	0.259	C	S	.	.			trans	-86	134	171.8	-172.1	-109.2	0	0	0	110.3	F89 H93 F101 G102 W105 C106 W109 T189 C191	F89-W99 HydrophobicContact CB-CH2 4.1Å; F89-W99 HydrophobicContact CB-CZ3 4.25Å; H93-W99 HydrophobicContact CB-CE3 4Å; H93-W99 HydrophobicContact CB-CZ3 4.27Å; W99-F101 AromaticContact CD2-CD2 3.88Å; W99-F101 HydrophobicContact CD2-CD2 3.88Å; W99-F101 AromaticContact CE2-CD2 3.8Å; W99-F101 AromaticContact CE3-CD2 3.91Å; W99-F101 HydrophobicContact CE3-CD2 3.91Å; W99-F101 HydrophobicContact CE3-CE2 4.45Å; W99-F101 AromaticContact CH2-CD2 3.81Å; W99-F101 HydrophobicContact CH2-CD2 3.81Å; W99-F101 HydrophobicContact CZ2-CB 3.77Å; W99-F101 AromaticContact CZ2-CD2 3.78Å; W99-F101 HydrophobicContact CZ2-CD2 3.78Å; W99-F101 HydrophobicContact CZ2-CG 4.2Å; W99-F101 AromaticContact CZ3-CD2 3.87Å; W99-F101 HydrophobicContact CZ3-CD2 3.87Å; W99-F101 HydrophobicContact CZ3-CE2 4.32Å; W99-G102 PolarHBondContact NE1-O 3.4Å; W99-W105 HydrophobicContact CZ2-CB 4.38Å; W99-W105 AromaticContact CZ2-CD1 3.61Å; W99-W105 HydrophobicContact CZ2-CG 4.32Å; W99-C106 HydrophobicContact CZ2-CB 4.12Å; W99-W109 HydrophobicContact CH2-CB 4.09Å; W99-W109 AromaticContact CH2-CD2 3.9Å; W99-W109 HydrophobicContact CH2-CD2 3.9Å; W99-W109 HydrophobicContact CH2-CE3 4.13Å; W99-W109 AromaticContact CH2-CG 3.87Å; W99-W109 HydrophobicContact CH2-CG 3.87Å; W99-W109 HydrophobicContact CZ2-CB 4.44Å; W99-W109 HydrophobicContact CZ3-CD2 4.29Å; W99-W109 HydrophobicContact CZ3-CE3 4.36Å; W99-T189 WeakPolarHBondContact CB-O 3.49Å; W99-T189 PolarHBondContact N-O 2.95Å; W99-T189 WeakPolarHBondContact O-CA 3.48Å; W99-C191 HydrophobicContact CB-CB 3.74Å; W99-C191 HydrophobicContact CD2-CB 3.54Å; W99-C191 HydrophobicContact CE3-CB 3.87Å; W99-C191 HydrophobicContact CG-CB 3.5Å; W99-C191 VanDerWaalsContact CG-CB 3.5Å
100	T	97.3	Very high	96.6	Very high	72 Å²	72	50.7 Å²	50.7	44%	0.442	25%	0.251	S	S	.	.			trans	-121.5	8.4	-177.2	60.6	0	0	0	0	113.4	M96 M98	M96-T100 HydrophobicContact SD-CG2 3.82Å; M98-T100 HydrophobicContact CG-CG2 4.05Å; M98-T100 HydrophobicContact SD-CG2 4.49Å
101	F	97.3	Very high	96.7	Very high	76 Å²	76	50.5 Å²	50.5	33%	0.333	25%	0.249	S	C	.	.	S	Bend	trans	-109.4	5.8	-172.2	-48.9	-79.2	0	0	0	113.3	F89 A92 W99 W105	F89-F101 HydrophobicContact CD1-CD1 4.16Å; F89-F101 AromaticContact CD1-CD2 3.99Å; F89-F101 HydrophobicContact CD1-CD2 3.99Å; F89-F101 AromaticContact CD1-CE1 3.95Å; F89-F101 HydrophobicContact CD1-CE1 3.95Å; F89-F101 AromaticContact CD1-CE2 3.78Å; F89-F101 HydrophobicContact CD1-CE2 3.78Å; F89-F101 HydrophobicContact CD1-CG 4.19Å; F89-F101 AromaticContact CD1-CZ 3.75Å; F89-F101 HydrophobicContact CD1-CZ 3.75Å; F89-F101 HydrophobicContact CE1-CD1 4.08Å; F89-F101 AromaticContact CE1-CE1 3.93Å; F89-F101 HydrophobicContact CE1-CE1 3.93Å; F89-F101 HydrophobicContact CE1-CG 4.47Å; F89-F101 HydrophobicContact CE1-CZ 4.19Å; A92-F101 HydrophobicContact CB-CE2 4.09Å; A92-F101 HydrophobicContact CB-CZ 4.03Å; W99-F101 AromaticContact CD2-CD2 3.88Å; W99-F101 HydrophobicContact CD2-CD2 3.88Å; W99-F101 AromaticContact CE2-CD2 3.8Å; W99-F101 AromaticContact CE3-CD2 3.91Å; W99-F101 HydrophobicContact CE3-CD2 3.91Å; W99-F101 HydrophobicContact CE3-CE2 4.45Å; W99-F101 AromaticContact CH2-CD2 3.81Å; W99-F101 HydrophobicContact CH2-CD2 3.81Å; W99-F101 HydrophobicContact CZ2-CB 3.77Å; W99-F101 AromaticContact CZ2-CD2 3.78Å; W99-F101 HydrophobicContact CZ2-CD2 3.78Å; W99-F101 HydrophobicContact CZ2-CG 4.2Å; W99-F101 AromaticContact CZ3-CD2 3.87Å; W99-F101 HydrophobicContact CZ3-CD2 3.87Å; W99-F101 HydrophobicContact CZ3-CE2 4.32Å; F101-W105 HydrophobicContact CB-CB 3.98Å; F101-W105 HydrophobicContact CB-CG 4.09Å; F101-W105 WeakPolarHBondContact O-CB 3.08Å
102	G	96.9	Very high	96.7	Very high	20 Å²	20	50.8 Å²	50.8	21%	0.206	25%	0.249	C	C	.	.	H	α-helix	trans	73.2	169.1	178.9	0	0	0	0	0	114.6	W99 F104 W105 C106	W99-G102 PolarHBondContact NE1-O 3.4Å; G102-F104 PolarHBondContact O-N 3.26Å; G102-W105 PolarHBondContact O-N 3.29Å; G102-C106 PolarHBondContact O-N 3.03Å; G102-C106 VanDerWaalsContact O-N 3.1Å
103	N	96	Very high	96.8	Very high	52 Å²	52	50.7 Å²	50.7	28%	0.278	25%	0.246	S	C	.	.	H	α-helix	trans	-65.3	-38.2	-172.8	-74.4	-11.1	0	0	0	113.6	W105 C106 E107 Y185 E188	N103-W105 PolarHBondContact O-N 3.33Å; N103-C106 WeakPolarHBondContact O-CB 3.48Å; N103-C106 PolarHBondContact O-N 3.07Å; N103-E107 PolarHBondContact O-N 3.26Å; N103-E107 VanDerWaalsContact O-N 3.09Å; N103-Y185 PolarHBondContact ND2-O 3.31Å; N103-Y185 VanDerWaalsContact ND2-O 3.14Å; N103-E188 WeakPolarHBondContact OD1-CA 3.45Å
104	F	96.8	Very high	96.9	Very high	152 Å²	152	50.3 Å²	50.3	67%	0.667	25%	0.246	S	C	*	.	H	α-helix	trans	-58.9	-49.9	178.7	172.7	-97.7	0	0	0	111.6	G102 C106 E107 F108	G102-F104 PolarHBondContact O-N 3.26Å; F104-C106 VanDerWaalsContact C-N 3.31Å; F104-C106 PolarHBondContact O-N 3Å; F104-E107 PolarHBondContact O-N 3.12Å; F104-F108 WeakPolarHBondContact O-CB 3.46Å; F104-F108 PolarHBondContact O-N 3.37Å; F104-F108 VanDerWaalsContact O-N 3.12Å
105	W	97.7	Very high	97	Very high	66 Å²	66	49.5 Å²	49.5	25%	0.25	24%	0.242	C	C	.	.	H	α-helix	trans	-69.9	-30.6	179	-166.5	-115.3	0	0	0	111.7	F89 W99 F101 G102 N103 F108 W109	F89-W105 AromaticContact CD1-CD1 4Å; F89-W105 AromaticContact CD1-NE1 3.36Å; F89-W105 AromaticContact CD2-NE1 3.97Å; F89-W105 HydrophobicContact CE1-CZ2 4.42Å; F89-W105 AromaticContact CE1-NE1 3.24Å; F89-W105 AromaticContact CE2-CZ2 3.85Å; F89-W105 HydrophobicContact CE2-CZ2 3.85Å; F89-W105 AromaticContact CE2-NE1 3.86Å; F89-W105 AromaticContact CG-NE1 3.73Å; F89-W105 AromaticContact CZ-CE2 3.9Å; F89-W105 AromaticContact CZ-CZ2 3.79Å; F89-W105 HydrophobicContact CZ-CZ2 3.79Å; F89-W105 AromaticContact CZ-NE1 3.5Å; W99-W105 HydrophobicContact CZ2-CB 4.38Å; W99-W105 AromaticContact CZ2-CD1 3.61Å; W99-W105 HydrophobicContact CZ2-CG 4.32Å; F101-W105 HydrophobicContact CB-CB 3.98Å; F101-W105 HydrophobicContact CB-CG 4.09Å; F101-W105 WeakPolarHBondContact O-CB 3.08Å; G102-W105 PolarHBondContact O-N 3.29Å; N103-W105 PolarHBondContact O-N 3.33Å; W105-F108 HydrophobicContact CE3-CB 4.29Å; W105-F108 AromaticContact CE3-CD1 3.84Å; W105-F108 HydrophobicContact CE3-CD1 3.84Å; W105-F108 HydrophobicContact CE3-CG 4.4Å; W105-F108 AromaticContact CH2-CD1 3.9Å; W105-F108 HydrophobicContact CH2-CD1 3.9Å; W105-F108 HydrophobicContact CH2-CE1 4.13Å; W105-F108 AromaticContact CZ3-CD1 3.35Å; W105-F108 HydrophobicContact CZ3-CD1 3.35Å; W105-F108 AromaticContact CZ3-CE1 3.76Å; W105-F108 HydrophobicContact CZ3-CE1 3.76Å; W105-F108 HydrophobicContact CZ3-CG 4.28Å; W105-F108 PolarHBondContact O-N 3.09Å; W105-W109 WeakPolarHBondContact O-CA 3.49Å; W105-W109 WeakPolarHBondContact O-CB 3.46Å; W105-W109 PolarHBondContact O-N 3.04Å
106	C	98	Very high	97.2	Very high	13 Å²	13	47.3 Å²	47.3	9%	0.088	23%	0.23	C	C	.	.	H	α-helix	trans	-58.8	-51	174.5	175.6	0	0	0	0	111.9	W99 G102 N103 F104 F108 W109 T110 C191	W99-C106 HydrophobicContact CZ2-CB 4.12Å; G102-C106 PolarHBondContact O-N 3.03Å; G102-C106 VanDerWaalsContact O-N 3.1Å; N103-C106 WeakPolarHBondContact O-CB 3.48Å; N103-C106 PolarHBondContact O-N 3.07Å; F104-C106 VanDerWaalsContact C-N 3.31Å; F104-C106 PolarHBondContact O-N 3Å; C106-F108 PolarHBondContact O-N 3.3Å; C106-W109 PolarHBondContact O-N 3.42Å; C106-T110 WeakPolarHBondContact O-CB 3.38Å; C106-T110 PolarHBondContact O-N 3.08Å; C106-T110 PolarHBondContact O-OG1 3.27Å; C106-C191 VanDerWaalsContact CA-SG 3.5Å; C106-C191 HydrophobicContact CB-CB 3.85Å; C106-C191 WeakPolarHBondContact CB-SG 3.48Å; C106-C191 WeakPolarHBondContact SG-CA 3.32Å; C106-C191 WeakPolarHBondContact SG-CB 3.44Å; C106-C191 CovalentContact SG-SG 2.03Å; C106-C191 PolarHBondContact SG-SG 3.15Å
107	E	97.4	Very high	97.3	Very high	26 Å²	26	42.9 Å²	42.9	12%	0.121	21%	0.209	C	C	.	.	H	α-helix	trans	-68.2	-37	-179.4	-66.9	-169.1	147.8	0	0	112.1	N103 F104 S111 I169 Q170 H172 Y174 R175	N103-E107 PolarHBondContact O-N 3.26Å; N103-E107 VanDerWaalsContact O-N 3.09Å; F104-E107 PolarHBondContact O-N 3.12Å; E107-S111 WeakPolarHBondContact O-CB 3.06Å; E107-S111 PolarHBondContact O-N 3.46Å; E107-S111 PolarHBondContact O-OG 2.86Å; E107-I169 HydrophobicContact CB-CG2 4.29Å; E107-Q170 PolarHBondContact O-NE2 2.71Å; E107-H172 IonicContact OE1-CE1 3.24Å; E107-H172 PolarHBondContact OE1-CE1 3.26Å; E107-H172 IonicContact OE1-ND1 3.67Å; E107-H172 PolarHBondContact OE1-ND1 3Å; E107-H172 IonicContact OE2-CE1 3.63Å; E107-H172 PolarHBondContact OE2-CE1 2.94Å; E107-H172 VanDerWaalsContact OE2-CE1 3.24Å; E107-H172 IonicContact OE2-ND1 2.95Å; E107-Y174 PolarHBondContact OE1-OH 3.32Å; E107-R175 IonicContact OE1-CZ 2.66Å; E107-R175 IonicContact OE1-NE 4Å; E107-R175 IonicContact OE1-NH2 2.84Å; E107-R175 PolarHBondContact OE1-NH2 3.34Å
108	F	98	Very high	97.6	Very high	68 Å²	68	35.6 Å²	35.6	30%	0.298	18%	0.177	S	C	.	.	H	α-helix	trans	-67.6	-45.3	175.8	-164.3	-99.9	0	0	0	112.2	F104 W105 C106 S111 I112 F166	F104-F108 WeakPolarHBondContact O-CB 3.46Å; F104-F108 PolarHBondContact O-N 3.37Å; F104-F108 VanDerWaalsContact O-N 3.12Å; W105-F108 HydrophobicContact CE3-CB 4.29Å; W105-F108 AromaticContact CE3-CD1 3.84Å; W105-F108 HydrophobicContact CE3-CD1 3.84Å; W105-F108 HydrophobicContact CE3-CG 4.4Å; W105-F108 AromaticContact CH2-CD1 3.9Å; W105-F108 HydrophobicContact CH2-CD1 3.9Å; W105-F108 HydrophobicContact CH2-CE1 4.13Å; W105-F108 AromaticContact CZ3-CD1 3.35Å; W105-F108 HydrophobicContact CZ3-CD1 3.35Å; W105-F108 AromaticContact CZ3-CE1 3.76Å; W105-F108 HydrophobicContact CZ3-CE1 3.76Å; W105-F108 HydrophobicContact CZ3-CG 4.28Å; W105-F108 PolarHBondContact O-N 3.09Å; C106-F108 PolarHBondContact O-N 3.3Å; F108-S111 WeakPolarHBondContact O-CB 3.25Å; F108-S111 PolarHBondContact O-N 3.06Å; F108-S111 VanDerWaalsContact O-N 3.16Å; F108-I112 HydrophobicContact CD1-CD1 3.56Å; F108-I112 HydrophobicContact CD1-CG1 4.29Å; F108-I112 HydrophobicContact CE1-CD1 3.33Å; F108-I112 HydrophobicContact CE1-CG1 4.17Å; F108-I112 HydrophobicContact CZ-CD1 4.19Å; F108-I112 WeakPolarHBondContact O-CG1 3.17Å; F108-I112 PolarHBondContact O-N 3.01Å; F108-F166 HydrophobicContact CD2-CE1 4.01Å; F108-F166 AromaticContact CE2-CE1 3.77Å; F108-F166 HydrophobicContact CE2-CE1 3.77Å; F108-F166 HydrophobicContact CE2-CZ 4.43Å; F108-F166 HydrophobicContact CZ-CE1 4.44Å
109	W	98.4	Very high	97.7	Very high	22 Å²	22	31.7 Å²	31.7	8%	0.083	16%	0.158	C	C	.	.	H	α-helix	trans	-58.1	-48.2	174.8	169.8	78	0	0	0	111.3	A85 V86 W99 W105 C106 S111 I112 D113	A85-W109 VanDerWaalsContact O-CD1 3.29Å; V86-W109 PolarHBondContact O-NE1 2.94Å; W99-W109 HydrophobicContact CH2-CB 4.09Å; W99-W109 AromaticContact CH2-CD2 3.9Å; W99-W109 HydrophobicContact CH2-CD2 3.9Å; W99-W109 HydrophobicContact CH2-CE3 4.13Å; W99-W109 AromaticContact CH2-CG 3.87Å; W99-W109 HydrophobicContact CH2-CG 3.87Å; W99-W109 HydrophobicContact CZ2-CB 4.44Å; W99-W109 HydrophobicContact CZ3-CD2 4.29Å; W99-W109 HydrophobicContact CZ3-CE3 4.36Å; W105-W109 WeakPolarHBondContact O-CA 3.49Å; W105-W109 WeakPolarHBondContact O-CB 3.46Å; W105-W109 PolarHBondContact O-N 3.04Å; C106-W109 PolarHBondContact O-N 3.42Å; W109-S111 VanDerWaalsContact C-N 3.28Å; W109-S111 PolarHBondContact O-N 3.28Å; W109-I112 PolarHBondContact O-N 3.32Å; W109-D113 PolarHBondContact O-N 3.42Å
110	T	98.1	Very high	97.8	Very high	8 Å²	8	31.9 Å²	31.9	5%	0.049	16%	0.159	C	C	.	.	H	α-helix	trans	-60	-39.7	175.8	-53.6	0	0	0	0	111.3	C106 D113 V114 I169 F193	C106-T110 WeakPolarHBondContact O-CB 3.38Å; C106-T110 PolarHBondContact O-N 3.08Å; C106-T110 PolarHBondContact O-OG1 3.27Å; T110-D113 PolarHBondContact O-N 2.69Å; T110-V114 WeakPolarHBondContact O-CG2 3.4Å; T110-V114 PolarHBondContact O-N 2.88Å; T110-V114 VanDerWaalsContact O-N 3.13Å; T110-I169 HydrophobicContact CG2-CD1 3.95Å; T110-F193 HydrophobicContact CG2-CD2 3.43Å; T110-F193 VanDerWaalsContact CG2-CD2 3.43Å; T110-F193 HydrophobicContact CG2-CE2 3.37Å; T110-F193 HydrophobicContact CG2-CG 4.18Å; T110-F193 HydrophobicContact CG2-CZ 4.04Å
111	S	98.2	Very high	97.8	Very high	0 Å²	0	28.4 Å²	28.4	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-65.5	-40	176.9	-57.4	0	0	0	0	112.7	E107 F108 W109 L115 I169 Q170	E107-S111 WeakPolarHBondContact O-CB 3.06Å; E107-S111 PolarHBondContact O-N 3.46Å; E107-S111 PolarHBondContact O-OG 2.86Å; F108-S111 WeakPolarHBondContact O-CB 3.25Å; F108-S111 PolarHBondContact O-N 3.06Å; F108-S111 VanDerWaalsContact O-N 3.16Å; W109-S111 VanDerWaalsContact C-N 3.28Å; W109-S111 PolarHBondContact O-N 3.28Å; S111-L115 VanDerWaalsContact O-CB 3.22Å; S111-L115 WeakPolarHBondContact O-CB 3.24Å; S111-L115 PolarHBondContact O-N 2.94Å; S111-I169 VanDerWaalsContact OG-CG2 3.32Å; S111-I169 WeakPolarHBondContact OG-CG2 3.42Å; S111-Q170 PolarHBondContact OG-NE2 3.28Å
112	I	98.4	Very high	97.8	Very high	17 Å²	17	26.1 Å²	26.1	9%	0.087	13%	0.129	C	C	.	.	H	α-helix	trans	-67.2	-41.6	176.5	-68.8	172.8	0	0	0	111	V81 A85 V86 F108 W109 L115 C116 F166	V81-I112 HydrophobicContact CG1-CG2 3.58Å; A85-I112 HydrophobicContact CB-CD1 4.33Å; A85-I112 HydrophobicContact CB-CG2 4.19Å; V86-I112 HydrophobicContact CG2-CB 4.33Å; V86-I112 HydrophobicContact CG2-CG2 3.65Å; F108-I112 HydrophobicContact CD1-CD1 3.56Å; F108-I112 HydrophobicContact CD1-CG1 4.29Å; F108-I112 HydrophobicContact CE1-CD1 3.33Å; F108-I112 HydrophobicContact CE1-CG1 4.17Å; F108-I112 HydrophobicContact CZ-CD1 4.19Å; F108-I112 WeakPolarHBondContact O-CG1 3.17Å; F108-I112 PolarHBondContact O-N 3.01Å; W109-I112 PolarHBondContact O-N 3.32Å; I112-L115 WeakPolarHBondContact O-CB 3.3Å; I112-L115 PolarHBondContact O-N 3.31Å; I112-C116 WeakPolarHBondContact O-CB 3.24Å; I112-C116 PolarHBondContact O-N 3.43Å; I112-C116 PolarHBondContact O-SG 2.9Å; I112-F166 HydrophobicContact CG1-CZ 4.02Å
113	D	98.2	Very high	97.9	Very high	17 Å²	17	25.3 Å²	25.3	9%	0.091	12%	0.119	C	C	.	.	H	α-helix	trans	-56.1	-58.1	176.7	-173.8	-1.5	0	0	0	110.5	V86 W109 T110 L115 C116 V117 Y316	V86-D113 HydrophobicContact CG1-CB 3.83Å; V86-D113 HydrophobicContact CG2-CB 4.18Å; W109-D113 PolarHBondContact O-N 3.42Å; T110-D113 PolarHBondContact O-N 2.69Å; D113-L115 VanDerWaalsContact C-N 3.28Å; D113-L115 PolarHBondContact O-N 3.06Å; D113-C116 PolarHBondContact O-N 3.06Å; D113-C116 VanDerWaalsContact O-N 3.12Å; D113-V117 WeakPolarHBondContact O-CG2 3.26Å; D113-V117 PolarHBondContact O-N 2.69Å; D113-V117 VanDerWaalsContact O-N 3.09Å; D113-Y316 WeakPolarHBondContact OD1-CE1 3.4Å; D113-Y316 PolarHBondContact OD2-OH 3.4Å
114	V	97.5	Very high	98	Very high	25 Å²	25	23 Å²	23	15%	0.152	11%	0.107	C	C	.	.	H	α-helix	trans	-60.2	-38.7	179.6	-177.7	0	0	0	0	111.5	T110 T118 S165 I169	T110-V114 WeakPolarHBondContact O-CG2 3.4Å; T110-V114 PolarHBondContact O-N 2.88Å; T110-V114 VanDerWaalsContact O-N 3.13Å; V114-T118 VanDerWaalsContact O-CB 3.29Å; V114-T118 WeakPolarHBondContact O-CB 3.1Å; V114-T118 PolarHBondContact O-N 2.97Å; V114-T118 PolarHBondContact O-OG1 2.92Å; V114-S165 PolarHBondContact O-OG 3.45Å; V114-I169 HydrophobicContact CB-CD1 4.46Å; V114-I169 HydrophobicContact CG2-CD1 4.13Å
115	L	98.2	Very high	98	Very high	21 Å²	21	16.6 Å²	16.6	11%	0.11	8%	0.081	C	C	.	.	H	α-helix	trans	-58.1	-51.8	175	165.4	63.6	0	0	0	111.4	S111 I112 D113 V117 T118 A119 W158 S165 F166	S111-L115 VanDerWaalsContact O-CB 3.22Å; S111-L115 WeakPolarHBondContact O-CB 3.24Å; S111-L115 PolarHBondContact O-N 2.94Å; I112-L115 WeakPolarHBondContact O-CB 3.3Å; I112-L115 PolarHBondContact O-N 3.31Å; D113-L115 VanDerWaalsContact C-N 3.28Å; D113-L115 PolarHBondContact O-N 3.06Å; L115-V117 PolarHBondContact O-N 3.43Å; L115-T118 PolarHBondContact O-N 3.41Å; L115-A119 HydrophobicContact CD1-CB 4.49Å; L115-A119 VanDerWaalsContact O-CB 3.23Å; L115-A119 WeakPolarHBondContact O-CB 3.49Å; L115-A119 PolarHBondContact O-N 3.24Å; L115-W158 HydrophobicContact CD1-CE3 4.27Å; L115-W158 HydrophobicContact CD2-CE3 4.45Å; L115-W158 HydrophobicContact CD2-CZ3 4.27Å; L115-W158 HydrophobicContact CG-CZ3 4.46Å; L115-S165 VanDerWaalsContact CA-OG 3.29Å; L115-S165 WeakPolarHBondContact CA-OG 3.26Å; L115-S165 PolarHBondContact N-OG 3.18Å; L115-F166 HydrophobicContact CB-CE2 4.03Å; L115-F166 HydrophobicContact CD2-CE2 3.7Å; L115-F166 HydrophobicContact CG-CE2 4.42Å
116	C	98.4	Very high	98	Very high	0 Å²	0	15 Å²	15	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-68.2	-37.5	-173.1	-67.5	0	0	0	0	112	V81 M82 I112 D113 S120	V81-C116 WeakPolarHBondContact CG1-SG 3.47Å; M82-C116 HydrophobicContact CG-CB 3.36Å; M82-C116 HydrophobicContact SD-CB 3.31Å; M82-C116 WeakPolarHBondContact SD-CB 3.28Å; I112-C116 WeakPolarHBondContact O-CB 3.24Å; I112-C116 PolarHBondContact O-N 3.43Å; I112-C116 PolarHBondContact O-SG 2.9Å; D113-C116 PolarHBondContact O-N 3.06Å; D113-C116 VanDerWaalsContact O-N 3.12Å; C116-S120 VanDerWaalsContact O-CB 3.27Å; C116-S120 WeakPolarHBondContact O-CB 3.29Å; C116-S120 PolarHBondContact O-N 3.47Å; C116-S120 PolarHBondContact O-OG 3.34Å
117	V	97.9	Very high	97.9	Very high	9 Å²	9	14.4 Å²	14.4	6%	0.055	7%	0.074	C	C	.	.	H	α-helix	trans	-64.8	-47.3	174.6	-179.7	0	0	0	0	110.7	M82 D113 L115 S120 I121 W286 F290	M82-V117 HydrophobicContact CE-CG2 4.17Å; D113-V117 WeakPolarHBondContact O-CG2 3.26Å; D113-V117 PolarHBondContact O-N 2.69Å; D113-V117 VanDerWaalsContact O-N 3.09Å; L115-V117 PolarHBondContact O-N 3.43Å; V117-S120 PolarHBondContact O-N 3.34Å; V117-I121 PolarHBondContact O-N 3.47Å; V117-I121 VanDerWaalsContact O-N 3.16Å; V117-W286 HydrophobicContact CB-CH2 4.38Å; V117-W286 HydrophobicContact CB-CZ2 4.4Å; V117-W286 HydrophobicContact CG1-CD2 4.07Å; V117-W286 HydrophobicContact CG1-CE3 4.08Å; V117-W286 HydrophobicContact CG1-CH2 4.17Å; V117-W286 HydrophobicContact CG1-CZ2 4.15Å; V117-W286 HydrophobicContact CG1-CZ3 4.13Å; V117-W286 HydrophobicContact CG2-CH2 3.27Å; V117-W286 HydrophobicContact CG2-CZ2 3.4Å; V117-W286 VanDerWaalsContact CG2-CZ2 3.4Å; V117-W286 HydrophobicContact CG2-CZ3 3.93Å; V117-F290 HydrophobicContact CG1-CE2 4.15Å; V117-F290 HydrophobicContact CG1-CZ 4.16Å
118	T	97.9	Very high	97.8	Very high	1 Å²	1	13.1 Å²	13.1	1%	0.006	7%	0.068	C	C	.	.	H	α-helix	trans	-63	-48.7	179.4	-52	0	0	0	0	111	V114 L115 S120 I121 E122 S207	V114-T118 VanDerWaalsContact O-CB 3.29Å; V114-T118 WeakPolarHBondContact O-CB 3.1Å; V114-T118 PolarHBondContact O-N 2.97Å; V114-T118 PolarHBondContact O-OG1 2.92Å; L115-T118 PolarHBondContact O-N 3.41Å; T118-S120 VanDerWaalsContact C-N 3.26Å; T118-S120 PolarHBondContact O-N 3.4Å; T118-I121 WeakPolarHBondContact O-CG2 3.45Å; T118-I121 PolarHBondContact O-N 2.98Å; T118-E122 HydrophobicContact CG2-CG 4.32Å; T118-E122 WeakPolarHBondContact O-CB 3.42Å; T118-E122 WeakPolarHBondContact O-CG 3.37Å; T118-E122 PolarHBondContact O-N 3.3Å; T118-S207 WeakPolarHBondContact OG1-CB 3.14Å; T118-S207 PolarHBondContact OG1-OG 3.05Å
119	A	98.4	Very high	97.7	Very high	0 Å²	0	12.2 Å²	12.2	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-62.2	-34.6	179.1	0	0	0	0	0	112	L115 T123 S161	L115-A119 HydrophobicContact CD1-CB 4.49Å; L115-A119 VanDerWaalsContact O-CB 3.23Å; L115-A119 WeakPolarHBondContact O-CB 3.49Å; L115-A119 PolarHBondContact O-N 3.24Å; A119-T123 WeakPolarHBondContact O-CB 3.4Å; A119-T123 PolarHBondContact O-N 2.97Å; A119-T123 PolarHBondContact O-OG1 2.7Å; A119-S161 VanDerWaalsContact CA-OG 3.22Å; A119-S161 WeakPolarHBondContact CA-OG 3.46Å; A119-S161 PolarHBondContact N-OG 2.87Å
120	S	98.3	Very high	97.5	Very high	4 Å²	4	11.5 Å²	11.5	3%	0.028	7%	0.066	C	C	.	.	H	α-helix	trans	-65.4	-51.7	177.5	-64.9	0	0	0	0	112	A78 C116 V117 T118 T123 L124	A78-S120 WeakPolarHBondContact CB-OG 3.49Å; C116-S120 VanDerWaalsContact O-CB 3.27Å; C116-S120 WeakPolarHBondContact O-CB 3.29Å; C116-S120 PolarHBondContact O-N 3.47Å; C116-S120 PolarHBondContact O-OG 3.34Å; V117-S120 PolarHBondContact O-N 3.34Å; T118-S120 VanDerWaalsContact C-N 3.26Å; T118-S120 PolarHBondContact O-N 3.4Å; S120-T123 PolarHBondContact O-N 2.95Å; S120-L124 WeakPolarHBondContact O-CG 3.43Å; S120-L124 PolarHBondContact O-N 3.21Å
121	I	97.8	Very high	97.2	Very high	0 Å²	0	13.2 Å²	13.2	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-70.3	-36.7	-179.6	-167.5	170.3	0	0	0	112.4	V117 T118 T123 L124 C125 S207 F208 P211 L212 F282	V117-I121 PolarHBondContact O-N 3.47Å; V117-I121 VanDerWaalsContact O-N 3.16Å; T118-I121 WeakPolarHBondContact O-CG2 3.45Å; T118-I121 PolarHBondContact O-N 2.98Å; I121-T123 VanDerWaalsContact C-N 3.33Å; I121-T123 PolarHBondContact O-N 3.38Å; I121-L124 PolarHBondContact O-N 3.38Å; I121-C125 WeakPolarHBondContact O-CB 3.16Å; I121-C125 PolarHBondContact O-N 3.03Å; I121-S207 WeakPolarHBondContact CG2-O 3.4Å; I121-F208 HydrophobicContact CD1-CD2 3.56Å; I121-F208 HydrophobicContact CD1-CE2 3.86Å; I121-F208 HydrophobicContact CD1-CG 4.26Å; I121-F208 WeakPolarHBondContact CD1-O 3.31Å; I121-P211 HydrophobicContact CD1-CB 4.04Å; I121-P211 HydrophobicContact CG1-CB 3.82Å; I121-P211 HydrophobicContact CG2-CB 4.13Å; I121-P211 HydrophobicContact CG2-CG 4.39Å; I121-L212 HydrophobicContact CD1-CB 3.9Å; I121-F282 HydrophobicContact CB-CE1 3.61Å; I121-F282 HydrophobicContact CB-CZ 3.66Å; I121-F282 HydrophobicContact CD1-CD1 4.44Å; I121-F282 HydrophobicContact CD1-CE1 3.77Å; I121-F282 HydrophobicContact CG1-CD1 4.4Å; I121-F282 HydrophobicContact CG1-CE1 3.8Å; I121-F282 HydrophobicContact CG1-CZ 4.37Å
122	E	97.8	Very high	97	Very high	28 Å²	28	17 Å²	17	13%	0.131	9%	0.087	C	C	.	.	H	α-helix	trans	-61.5	-42.9	172.7	-74.8	-172.9	172.8	0	0	111.1	T118 L124 C125 V126 V157 S161 P211	T118-E122 HydrophobicContact CG2-CG 4.32Å; T118-E122 WeakPolarHBondContact O-CB 3.42Å; T118-E122 WeakPolarHBondContact O-CG 3.37Å; T118-E122 PolarHBondContact O-N 3.3Å; E122-L124 PolarHBondContact O-N 3.45Å; E122-C125 WeakPolarHBondContact O-CB 3.22Å; E122-C125 PolarHBondContact O-N 3.17Å; E122-V126 WeakPolarHBondContact O-CG2 3.34Å; E122-V126 PolarHBondContact O-N 3.15Å; E122-V157 HydrophobicContact CB-CG1 3.74Å; E122-S161 VanDerWaalsContact CD-OG 3.28Å; E122-S161 PolarHBondContact OE2-OG 3.46Å; E122-P211 HydrophobicContact CG-CG 4.38Å
123	T	98.3	Very high	96.7	Very high	2 Å²	2	20.8 Å²	20.8	1%	0.012	10%	0.103	C	C	.	.	H	α-helix	trans	-61.1	-42.8	174.2	-62	0	0	0	0	111.4	F71 S74 L75 A119 S120 I121 C125 V126 I127	F71-T123 HydrophobicContact CB-CG2 4.19Å; F71-T123 VanDerWaalsContact O-CG2 3.23Å; F71-T123 WeakPolarHBondContact O-CG2 3.45Å; S74-T123 PolarHBondContact OG-OG1 2.91Å; L75-T123 HydrophobicContact CB-CG2 4.1Å; A119-T123 WeakPolarHBondContact O-CB 3.4Å; A119-T123 PolarHBondContact O-N 2.97Å; A119-T123 PolarHBondContact O-OG1 2.7Å; S120-T123 PolarHBondContact O-N 2.95Å; I121-T123 VanDerWaalsContact C-N 3.33Å; I121-T123 PolarHBondContact O-N 3.38Å; T123-C125 VanDerWaalsContact C-N 3.35Å; T123-C125 PolarHBondContact O-N 2.93Å; T123-V126 PolarHBondContact O-N 2.98Å; T123-I127 HydrophobicContact CG2-CD1 4.12Å; T123-I127 VanDerWaalsContact O-CG1 3.32Å; T123-I127 WeakPolarHBondContact O-CG1 3.45Å; T123-I127 PolarHBondContact O-N 3.47Å
124	L	97.4	Very high	96.4	Very high	3 Å²	3	20.9 Å²	20.9	2%	0.016	11%	0.106	C	C	.	.	H	α-helix	trans	-64.4	-38.8	176.2	-69.6	173.4	0	0	0	112.4	L75 S120 I121 E122 I127 A128 M215 I278 M279 F282	L75-L124 HydrophobicContact CD2-CD2 3.84Å; L75-L124 HydrophobicContact CD2-CG 4.47Å; S120-L124 WeakPolarHBondContact O-CG 3.43Å; S120-L124 PolarHBondContact O-N 3.21Å; I121-L124 PolarHBondContact O-N 3.38Å; E122-L124 PolarHBondContact O-N 3.45Å; L124-I127 HydrophobicContact CD2-CD1 4.44Å; L124-I127 PolarHBondContact O-N 3.02Å; L124-A128 PolarHBondContact O-N 3.41Å; L124-M215 HydrophobicContact CB-SD 3.54Å; L124-M215 VanDerWaalsContact CB-SD 3.54Å; L124-M215 HydrophobicContact CD1-SD 4.31Å; L124-I278 HydrophobicContact CD2-CG2 3.68Å; L124-M279 HydrophobicContact CD2-CG 4.18Å; L124-F282 HydrophobicContact CD1-CB 3.58Å; L124-F282 HydrophobicContact CD1-CD1 3.98Å; L124-F282 HydrophobicContact CD1-CD2 3.65Å; L124-F282 HydrophobicContact CD1-CE2 4.39Å; L124-F282 HydrophobicContact CD1-CG 3.44Å; L124-F282 VanDerWaalsContact CD1-CG 3.44Å
125	C	97.4	Very high	95.9	Very high	18 Å²	18	20.7 Å²	20.7	12%	0.122	10%	0.103	C	C	.	.	H	α-helix	trans	-61.7	-44.8	173.4	-177.1	0	0	0	0	111.2	I121 E122 T123 I127 A128 V129 P211 I214 M215	I121-C125 WeakPolarHBondContact O-CB 3.16Å; I121-C125 PolarHBondContact O-N 3.03Å; E122-C125 WeakPolarHBondContact O-CB 3.22Å; E122-C125 PolarHBondContact O-N 3.17Å; T123-C125 VanDerWaalsContact C-N 3.35Å; T123-C125 PolarHBondContact O-N 2.93Å; C125-I127 PolarHBondContact O-N 3.4Å; C125-A128 WeakPolarHBondContact O-CB 3.48Å; C125-A128 PolarHBondContact O-N 2.92Å; C125-A128 VanDerWaalsContact O-N 3.17Å; C125-V129 WeakPolarHBondContact O-CG2 3.41Å; C125-V129 PolarHBondContact O-N 3.37Å; C125-P211 HydrophobicContact CB-CB 4.44Å; C125-I214 WeakPolarHBondContact SG-CG2 3.39Å; C125-M215 HydrophobicContact CB-CB 4.34Å
126	V	97.2	Very high	95.5	Very high	32 Å²	32	22.2 Å²	22.2	19%	0.194	11%	0.114	C	C	.	.	H	α-helix	trans	-60.7	-43.2	174.1	171.2	0	0	0	0	111.4	F71 E122 T123 A128 V129 D130 I153 V157	F71-V126 HydrophobicContact CD1-CG1 3.82Å; F71-V126 HydrophobicContact CD2-CG1 4.39Å; F71-V126 HydrophobicContact CE1-CG1 3.42Å; F71-V126 VanDerWaalsContact CE1-CG1 3.42Å; F71-V126 HydrophobicContact CE2-CG1 4.04Å; F71-V126 HydrophobicContact CG-CG1 4.3Å; F71-V126 HydrophobicContact CZ-CG1 3.55Å; E122-V126 WeakPolarHBondContact O-CG2 3.34Å; E122-V126 PolarHBondContact O-N 3.15Å; T123-V126 PolarHBondContact O-N 2.98Å; V126-A128 VanDerWaalsContact C-N 3.3Å; V126-A128 PolarHBondContact O-N 2.94Å; V126-V129 PolarHBondContact O-N 3.3Å; V126-D130 VanDerWaalsContact O-CB 3.22Å; V126-D130 WeakPolarHBondContact O-CB 3.18Å; V126-D130 PolarHBondContact O-N 2.82Å; V126-I153 HydrophobicContact CG1-CG2 3.76Å; V126-I153 HydrophobicContact CG2-CG2 4.11Å; V126-V157 HydrophobicContact CG2-CG2 3.97Å
127	I	96.4	Very high	95	Very high	1 Å²	1	24 Å²	24	1%	0.005	13%	0.126	C	C	.	.	H	α-helix	trans	-59.7	-41.2	174.9	-69.1	166.6	0	0	0	110.9	F71 T123 L124 C125 D130 R131 L275 M279	F71-I127 HydrophobicContact CB-CD1 3.85Å; F71-I127 HydrophobicContact CB-CG1 3.47Å; F71-I127 VanDerWaalsContact CB-CG1 3.47Å; F71-I127 HydrophobicContact CD2-CG1 4.33Å; F71-I127 HydrophobicContact CG-CG1 4.15Å; T123-I127 HydrophobicContact CG2-CD1 4.12Å; T123-I127 VanDerWaalsContact O-CG1 3.32Å; T123-I127 WeakPolarHBondContact O-CG1 3.45Å; T123-I127 PolarHBondContact O-N 3.47Å; L124-I127 HydrophobicContact CD2-CD1 4.44Å; L124-I127 PolarHBondContact O-N 3.02Å; C125-I127 PolarHBondContact O-N 3.4Å; I127-D130 PolarHBondContact O-N 3Å; I127-R131 HydrophobicContact CG2-CG 4.34Å; I127-R131 WeakPolarHBondContact O-CB 3.21Å; I127-R131 VanDerWaalsContact O-CG 3.28Å; I127-R131 WeakPolarHBondContact O-CG 3.22Å; I127-R131 PolarHBondContact O-N 3.08Å; I127-L275 HydrophobicContact CG2-CD1 4.09Å; I127-L275 HydrophobicContact CG2-CD2 4.14Å; I127-M279 HydrophobicContact CB-CE 4.09Å; I127-M279 HydrophobicContact CG2-CE 3.69Å
128	A	96.1	Very high	94.3	Very high	0 Å²	0	27 Å²	27	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-62.3	-45.7	177.9	0	0	0	0	0	111.8	L124 C125 V126 R131 Y132 M215 V218 Y219 M279	L124-A128 PolarHBondContact O-N 3.41Å; C125-A128 WeakPolarHBondContact O-CB 3.48Å; C125-A128 PolarHBondContact O-N 2.92Å; C125-A128 VanDerWaalsContact O-N 3.17Å; V126-A128 VanDerWaalsContact C-N 3.3Å; V126-A128 PolarHBondContact O-N 2.94Å; A128-R131 PolarHBondContact O-N 3.27Å; A128-Y132 PolarHBondContact O-N 3.19Å; A128-M215 HydrophobicContact CB-CG 4.15Å; A128-V218 HydrophobicContact CB-CB 4.31Å; A128-V218 HydrophobicContact CB-CG1 4.1Å; A128-V218 WeakPolarHBondContact O-CG1 3.43Å; A128-Y219 HydrophobicContact CB-CD2 3.93Å; A128-M279 HydrophobicContact CB-CE 3.86Å; A128-M279 HydrophobicContact CB-SD 4.29Å
129	V	95	Very high	93.6	Very high	49 Å²	49	35.9 Å²	35.9	30%	0.297	19%	0.185	S	C	.	.	H	α-helix	trans	-65.1	-43.7	177.2	175.1	0	0	0	0	111.5	C125 V126 R131 Y132 F133 V218	C125-V129 WeakPolarHBondContact O-CG2 3.41Å; C125-V129 PolarHBondContact O-N 3.37Å; V126-V129 PolarHBondContact O-N 3.3Å; V129-R131 PolarHBondContact O-N 2.84Å; V129-Y132 WeakPolarHBondContact O-CB 3.36Å; V129-Y132 PolarHBondContact O-N 2.74Å; V129-Y132 VanDerWaalsContact O-N 3.15Å; V129-F133 HydrophobicContact CG1-CD2 3.75Å; V129-F133 HydrophobicContact CG1-CE2 3.52Å; V129-F133 VanDerWaalsContact O-CD2 3.29Å; V129-F133 WeakPolarHBondContact O-CD2 3.29Å; V129-F133 PolarHBondContact O-N 3.45Å; V129-V218 HydrophobicContact CG2-CG1 4.26Å; V129-V218 HydrophobicContact CG2-CG2 4.33Å
130	D	93.9	Very high	92.9	Very high	7 Å²	7	42.6 Å²	42.6	4%	0.037	21%	0.214	C	C	.	.	H	α-helix	trans	-54.5	-51	173.3	165.3	62.8	0	0	0	111.4	T68 F71 V126 I127 Y132 F133 A134 Y141 L145	T68-D130 PolarHBondContact OG1-OD2 3.39Å; F71-D130 HydrophobicContact CE2-CB 4.09Å; V126-D130 VanDerWaalsContact O-CB 3.22Å; V126-D130 WeakPolarHBondContact O-CB 3.18Å; V126-D130 PolarHBondContact O-N 2.82Å; I127-D130 PolarHBondContact O-N 3Å; D130-Y132 VanDerWaalsContact C-N 3.29Å; D130-Y132 PolarHBondContact O-N 2.87Å; D130-F133 PolarHBondContact O-N 2.96Å; D130-A134 WeakPolarHBondContact O-CB 3.38Å; D130-A134 PolarHBondContact O-N 3.09Å; D130-Y141 WeakPolarHBondContact OD1-CE2 3.32Å; D130-Y141 PolarHBondContact OD1-OH 2.86Å; D130-L145 WeakPolarHBondContact OD1-CD2 3.11Å
131	R	93.4	Very high	92.4	Very high	44 Å²	44	44 Å²	44	17%	0.166	22%	0.219	C	C	.	.	H	α-helix	trans	-64	-33.3	177.1	-67.2	-55.1	84.6	-160.4	-8.5	112.8	T68 I127 A128 V129 A134 I135 Y141 V222 L272 L275	T68-R131 PolarHBondContact OG1-NE 2.96Å; T68-R131 PolarHBondContact OG1-NH2 2.96Å; I127-R131 HydrophobicContact CG2-CG 4.34Å; I127-R131 WeakPolarHBondContact O-CB 3.21Å; I127-R131 VanDerWaalsContact O-CG 3.28Å; I127-R131 WeakPolarHBondContact O-CG 3.22Å; I127-R131 PolarHBondContact O-N 3.08Å; A128-R131 PolarHBondContact O-N 3.27Å; V129-R131 PolarHBondContact O-N 2.84Å; R131-A134 PolarHBondContact O-N 3.31Å; R131-I135 WeakPolarHBondContact O-CB 3.35Å; R131-I135 WeakPolarHBondContact O-CG2 3.37Å; R131-I135 PolarHBondContact O-N 3.1Å; R131-Y141 PolarHBondContact NH2-OH 2.93Å; R131-V222 HydrophobicContact CB-CG1 4.23Å; R131-V222 HydrophobicContact CB-CG2 4.24Å; R131-L272 HydrophobicContact CB-CD2 4.22Å; R131-L272 HydrophobicContact CG-CD2 4.18Å; R131-L275 HydrophobicContact CG-CD1 3.62Å
132	Y	93.2	Very high	91.4	Very high	79 Å²	79	51.6 Å²	51.6	31%	0.31	26%	0.255	S	S	.	.	H	α-helix	trans	-64.9	-45.4	174.9	179.7	-98.6	0	0	0	112.6	A128 V129 D130 I135 T136 V218 R221 V222	A128-Y132 PolarHBondContact O-N 3.19Å; V129-Y132 WeakPolarHBondContact O-CB 3.36Å; V129-Y132 PolarHBondContact O-N 2.74Å; V129-Y132 VanDerWaalsContact O-N 3.15Å; D130-Y132 VanDerWaalsContact C-N 3.29Å; D130-Y132 PolarHBondContact O-N 2.87Å; Y132-I135 WeakPolarHBondContact O-CG2 3.43Å; Y132-I135 PolarHBondContact O-N 3.32Å; Y132-T136 HydrophobicContact CD2-CG2 4.04Å; Y132-T136 HydrophobicContact CE1-CG2 4.22Å; Y132-T136 HydrophobicContact CE2-CG2 3.66Å; Y132-T136 HydrophobicContact CG-CG2 4.47Å; Y132-T136 WeakPolarHBondContact O-CB 3.46Å; Y132-T136 WeakPolarHBondContact O-CG2 3.4Å; Y132-T136 PolarHBondContact O-N 2.84Å; Y132-T136 PolarHBondContact O-OG1 3.43Å; Y132-V218 HydrophobicContact CG-CG1 4.17Å; Y132-R221 HydrophobicContact CD2-CB 4.12Å; Y132-R221 HydrophobicContact CE2-CB 3.94Å; Y132-V222 HydrophobicContact CD2-CG2 4.26Å
133	F	92.3	Very high	90.6	Very high	97 Å²	97	54.1 Å²	54.1	43%	0.425	28%	0.275	S	S	.	.	H	α-helix	trans	-67.7	-39.2	175.1	-75.9	-66.3	0	0	0	112.3	V129 D130 I135 S137 Y141	V129-F133 HydrophobicContact CG1-CD2 3.75Å; V129-F133 HydrophobicContact CG1-CE2 3.52Å; V129-F133 VanDerWaalsContact O-CD2 3.29Å; V129-F133 WeakPolarHBondContact O-CD2 3.29Å; V129-F133 PolarHBondContact O-N 3.45Å; D130-F133 PolarHBondContact O-N 2.96Å; F133-I135 VanDerWaalsContact C-N 3.31Å; F133-I135 PolarHBondContact O-N 3.31Å; F133-S137 PolarHBondContact O-N 3.3Å; F133-Y141 HydrophobicContact CB-CD2 4.25Å
134	A	91.1	Very high	89.9	Confident	19 Å²	19	58.1 Å²	58.1	16%	0.157	30%	0.296	C	S	.	.	H	α-helix	trans	-59.2	-41.1	176.6	0	0	0	0	0	112.5	D130 R131 Y141	D130-A134 WeakPolarHBondContact O-CB 3.38Å; D130-A134 PolarHBondContact O-N 3.09Å; R131-A134 PolarHBondContact O-N 3.31Å; A134-Y141 HydrophobicContact CB-CD1 4.15Å; A134-Y141 HydrophobicContact CB-CD2 3.73Å; A134-Y141 HydrophobicContact CB-CE1 4.23Å; A134-Y141 HydrophobicContact CB-CE2 3.79Å; A134-Y141 HydrophobicContact CB-CG 3.92Å
135	I	88.7	Confident	89.5	Confident	20 Å²	20	59.4 Å²	59.4	10%	0.103	30%	0.303	C	S	.	.	H	α-helix	trans	-82.5	-35.5	-177.1	-161.5	166.1	0	0	0	113.8	R131 Y132 F133 V222 E225 A226 Q229 L272	R131-I135 WeakPolarHBondContact O-CB 3.35Å; R131-I135 WeakPolarHBondContact O-CG2 3.37Å; R131-I135 PolarHBondContact O-N 3.1Å; Y132-I135 WeakPolarHBondContact O-CG2 3.43Å; Y132-I135 PolarHBondContact O-N 3.32Å; F133-I135 VanDerWaalsContact C-N 3.31Å; F133-I135 PolarHBondContact O-N 3.31Å; I135-V222 HydrophobicContact CG2-CG1 4.46Å; I135-E225 HydrophobicContact CD1-CB 4.28Å; I135-E225 HydrophobicContact CG1-CG 4.34Å; I135-E225 HydrophobicContact CG2-CB 4.37Å; I135-E225 HydrophobicContact CG2-CG 4.48Å; I135-A226 VanDerWaalsContact CD1-CA 3.47Å; I135-A226 HydrophobicContact CD1-CB 3.51Å; I135-A226 VanDerWaalsContact CD1-N 3.33Å; I135-Q229 PolarHBondContact O-NE2 3.21Å; I135-L272 HydrophobicContact CD1-CD1 4.07Å
136	T	89.7	Confident	89.3	Confident	53 Å²	53	61.3 Å²	61.3	33%	0.325	31%	0.314	S	S	.	.	H	α-helix	trans	-83.2	-26	-177.4	56.3	0	0	0	0	112.8	Y132 E225	Y132-T136 HydrophobicContact CD2-CG2 4.04Å; Y132-T136 HydrophobicContact CE1-CG2 4.22Å; Y132-T136 HydrophobicContact CE2-CG2 3.66Å; Y132-T136 HydrophobicContact CG-CG2 4.47Å; Y132-T136 WeakPolarHBondContact O-CB 3.46Å; Y132-T136 WeakPolarHBondContact O-CG2 3.4Å; Y132-T136 PolarHBondContact O-N 2.84Å; Y132-T136 PolarHBondContact O-OG1 3.43Å; T136-E225 HydrophobicContact CG2-CG 4.49Å
137	S	87.1	Confident	89.1	Confident	38 Å²	38	64.2 Å²	64.2	27%	0.266	32%	0.324	S	S	.	.			trans	-138.8	64.4	-174.4	-61.8	0	0	0	0	112	F133 F139 K140 Y141	F133-S137 PolarHBondContact O-N 3.3Å; S137-F139 PolarHBondContact O-N 3.01Å; S137-K140 PolarHBondContact O-N 3.22Å; S137-K140 VanDerWaalsContact O-N 3.16Å; S137-Y141 VanDerWaalsContact O-CB 3.28Å; S137-Y141 WeakPolarHBondContact O-CB 3.41Å; S137-Y141 PolarHBondContact O-N 3.03Å
138	P	82.9	Confident	88.9	Confident	72 Å²	72	69.1 Å²	69.1	47%	0.468	35%	0.35	S	S	.	.	H	α-helix	trans	-57.2	-41.7	-171.6	21.3	-33.5	0	0	0	114
139	F	83.1	Confident	88.9	Confident	188 Å²	188	74 Å²	74	83%	0.825	37%	0.371	S	S	*	.	H	α-helix	trans	-75.8	-30.8	-179.7	-58.7	-63	0	0	0	113.5	S137	S137-F139 PolarHBondContact O-N 3.01Å
140	K	84.1	Confident	89	Confident	141 Å²	141	71.7 Å²	71.7	61%	0.613	36%	0.357	S	S	*	.	H	α-helix	trans	-83.2	-28	176.6	-61.9	-176.9	176.5	-178.8	0	111.7	S137 Q142 S143 L144	S137-K140 PolarHBondContact O-N 3.22Å; S137-K140 VanDerWaalsContact O-N 3.16Å; K140-Q142 VanDerWaalsContact C-N 3.28Å; K140-Q142 PolarHBondContact O-N 3.03Å; K140-S143 PolarHBondContact O-N 3.47Å; K140-S143 VanDerWaalsContact O-N 3.1Å; K140-S143 PolarHBondContact O-OG 3.39Å; K140-L144 HydrophobicContact CB-CD1 3.9Å; K140-L144 HydrophobicContact CB-CG 4.3Å; K140-L144 WeakPolarHBondContact O-CB 3.35Å; K140-L144 WeakPolarHBondContact O-CG 3.31Å; K140-L144 PolarHBondContact O-N 3.25Å
141	Y	86.7	Confident	89.1	Confident	34 Å²	34	77.2 Å²	77.2	13%	0.133	38%	0.378	C	S	.	.	H	α-helix	trans	-57.2	-42.5	-176.8	171.9	-97.9	0	0	0	112.2	D130 R131 F133 A134 S137 S143 L144 L145	D130-Y141 WeakPolarHBondContact OD1-CE2 3.32Å; D130-Y141 PolarHBondContact OD1-OH 2.86Å; R131-Y141 PolarHBondContact NH2-OH 2.93Å; F133-Y141 HydrophobicContact CB-CD2 4.25Å; A134-Y141 HydrophobicContact CB-CD1 4.15Å; A134-Y141 HydrophobicContact CB-CD2 3.73Å; A134-Y141 HydrophobicContact CB-CE1 4.23Å; A134-Y141 HydrophobicContact CB-CE2 3.79Å; A134-Y141 HydrophobicContact CB-CG 3.92Å; S137-Y141 VanDerWaalsContact O-CB 3.28Å; S137-Y141 WeakPolarHBondContact O-CB 3.41Å; S137-Y141 PolarHBondContact O-N 3.03Å; Y141-S143 VanDerWaalsContact C-N 3.27Å; Y141-S143 PolarHBondContact O-N 3.07Å; Y141-L144 PolarHBondContact O-N 3.06Å; Y141-L145 HydrophobicContact CE2-CB 4.18Å; Y141-L145 HydrophobicContact CE2-CD2 3.94Å; Y141-L145 PolarHBondContact O-N 3.28Å; Y141-L145 VanDerWaalsContact O-N 3.08Å
142	Q	78.1	Confident	89.3	Confident	159 Å²	159	79.5 Å²	79.5	74%	0.743	40%	0.396	S	S	*	.	H	α-helix	trans	-61.4	-32.7	178.9	-68.1	-178.4	-16.8	0	0	113	K140	K140-Q142 VanDerWaalsContact C-N 3.28Å; K140-Q142 PolarHBondContact O-N 3.03Å
143	S	80.4	Confident	89.6	Confident	80 Å²	80	78.6 Å²	78.6	56%	0.559	40%	0.396	S	S	*	.	H	α-helix	trans	-88.6	-30.2	175.9	63.8	0	0	0	0	113.4	K140 Y141	K140-S143 PolarHBondContact O-N 3.47Å; K140-S143 VanDerWaalsContact O-N 3.1Å; K140-S143 PolarHBondContact O-OG 3.39Å; Y141-S143 VanDerWaalsContact C-N 3.27Å; Y141-S143 PolarHBondContact O-N 3.07Å
144	L	84.1	Confident	89.8	Confident	87 Å²	87	75.3 Å²	75.3	46%	0.455	38%	0.383	S	S	.	.	H	α-helix	trans	-68.5	-45.6	-179.4	-74.1	171.6	0	0	0	111.9	K140 Y141 K149	K140-L144 HydrophobicContact CB-CD1 3.9Å; K140-L144 HydrophobicContact CB-CG 4.3Å; K140-L144 WeakPolarHBondContact O-CB 3.35Å; K140-L144 WeakPolarHBondContact O-CG 3.31Å; K140-L144 PolarHBondContact O-N 3.25Å; Y141-L144 PolarHBondContact O-N 3.06Å; L144-K149 WeakPolarHBondContact O-CD 3.31Å; L144-K149 PolarHBondContact O-NZ 3.47Å
145	L	89.5	Confident	90.2	Very high	29 Å²	29	79.5 Å²	79.5	15%	0.152	40%	0.402	C	S	.	.			trans	-120.6	90.4	-169.8	-161.5	67.6	0	0	0	112.4	V67 F71 D130 Y141 K149 I153	V67-L145 HydrophobicContact CG1-CD2 3.42Å; V67-L145 VanDerWaalsContact CG1-CD2 3.42Å; V67-L145 HydrophobicContact CG1-CG 3.83Å; F71-L145 HydrophobicContact CE2-CD2 4.26Å; D130-L145 WeakPolarHBondContact OD1-CD2 3.11Å; Y141-L145 HydrophobicContact CE2-CB 4.18Å; Y141-L145 HydrophobicContact CE2-CD2 3.94Å; Y141-L145 PolarHBondContact O-N 3.28Å; Y141-L145 VanDerWaalsContact O-N 3.08Å; L145-K149 HydrophobicContact CD1-CB 4.36Å; L145-I153 HydrophobicContact CD1-CD1 3.71Å
146	T	92.2	Very high	90.6	Very high	59 Å²	59	83.2 Å²	83.2	36%	0.362	42%	0.42	S	S	.	.			trans	-82.4	161.2	174	69.3	0	0	0	0	111.3	N148 K149 A150	T146-N148 PolarHBondContact O-N 2.95Å; T146-K149 PolarHBondContact O-N 2.96Å; T146-K149 VanDerWaalsContact O-N 3.15Å; T146-K149 WeakPolarHBondContact OG1-CG 3.33Å; T146-K149 PolarHBondContact OG1-N 3.48Å; T146-A150 PolarHBondContact O-N 3.4Å
147	K	92.4	Very high	91.1	Very high	92 Å²	92	81.4 Å²	81.4	40%	0.4	41%	0.409	S	S	.	.	H	α-helix	trans	-54.9	-37.8	175.4	-66	-177.6	-177.1	179.8	0	112.3	Q65 V67 Y70 A150 R151	Q65-K147 WeakPolarHBondContact O-CE 3.24Å; Q65-K147 PolarHBondContact O-NZ 3.05Å; V67-K147 HydrophobicContact CG2-CG 4.46Å; Y70-K147 HydrophobicContact CE1-CB 4.04Å; Y70-K147 HydrophobicContact CE1-CG 4.43Å; K147-A150 PolarHBondContact O-N 3.24Å; K147-R151 WeakPolarHBondContact O-CG 3.27Å; K147-R151 PolarHBondContact O-N 3.29Å; K147-R151 VanDerWaalsContact O-N 3.11Å
148	N	94.1	Very high	91.6	Very high	105 Å²	105	82.8 Å²	82.8	56%	0.561	41%	0.408	S	S	*	.	H	α-helix	trans	-67.7	-45	177.8	-70	-11.6	0	0	0	111.8	T146 A150 R151 V152	T146-N148 PolarHBondContact O-N 2.95Å; N148-A150 VanDerWaalsContact C-N 3.28Å; N148-A150 PolarHBondContact O-N 2.92Å; N148-R151 PolarHBondContact O-N 2.96Å; N148-R151 PolarHBondContact OD1-NH1 3.39Å; N148-V152 PolarHBondContact O-N 3.49Å; N148-V152 VanDerWaalsContact O-N 3.1Å
149	K	95.6	Very high	92.3	Very high	102 Å²	102	83 Å²	83	44%	0.443	41%	0.405	S	S	.	.	H	α-helix	trans	-60.4	-39.8	174.7	-70.8	175.5	179.4	174.4	0	111.4	L144 L145 T146 R151 V152 I153	L144-K149 WeakPolarHBondContact O-CD 3.31Å; L144-K149 PolarHBondContact O-NZ 3.47Å; L145-K149 HydrophobicContact CD1-CB 4.36Å; T146-K149 PolarHBondContact O-N 2.96Å; T146-K149 VanDerWaalsContact O-N 3.15Å; T146-K149 WeakPolarHBondContact OG1-CG 3.33Å; T146-K149 PolarHBondContact OG1-N 3.48Å; K149-R151 PolarHBondContact O-N 3.25Å; K149-V152 PolarHBondContact O-N 3.01Å; K149-I153 WeakPolarHBondContact O-CG1 3.31Å; K149-I153 PolarHBondContact O-N 3.29Å
150	A	96.2	Very high	93	Very high	0 Å²	0	77 Å²	77	0%	0	38%	0.383	C	S	.	.	H	α-helix	trans	-60.9	-41.9	175.5	0	0	0	0	0	112.6	V67 F71 T146 K147 N148 V152 I153 I154	V67-A150 HydrophobicContact CG1-CB 3.8Å; F71-A150 HydrophobicContact CE1-CB 4.49Å; F71-A150 HydrophobicContact CZ-CB 4.11Å; T146-A150 PolarHBondContact O-N 3.4Å; K147-A150 PolarHBondContact O-N 3.24Å; N148-A150 VanDerWaalsContact C-N 3.28Å; N148-A150 PolarHBondContact O-N 2.92Å; A150-V152 PolarHBondContact O-N 3.44Å; A150-I153 PolarHBondContact O-N 3.46Å; A150-I154 VanDerWaalsContact O-CG1 3.32Å; A150-I154 WeakPolarHBondContact O-CG1 3.21Å; A150-I154 PolarHBondContact O-N 2.94Å
151	R	96.9	Very high	93.7	Very high	124 Å²	124	70.2 Å²	70.2	47%	0.468	35%	0.354	S	S	.	.	H	α-helix	trans	-62.6	-39.9	174.6	-67.8	179.4	-163.4	133	4	112.5	Y70 K147 N148 K149 I154 L155	Y70-R151 HydrophobicContact CD1-CG 4.11Å; Y70-R151 HydrophobicContact CE1-CG 4.06Å; Y70-R151 PolarHBondContact OH-NH2 3.07Å; K147-R151 WeakPolarHBondContact O-CG 3.27Å; K147-R151 PolarHBondContact O-N 3.29Å; K147-R151 VanDerWaalsContact O-N 3.11Å; N148-R151 PolarHBondContact O-N 2.96Å; N148-R151 PolarHBondContact OD1-NH1 3.39Å; K149-R151 PolarHBondContact O-N 3.25Å; R151-I154 PolarHBondContact O-N 3.06Å; R151-L155 PolarHBondContact O-N 3.45Å
152	V	97.9	Very high	94.2	Very high	91 Å²	91	69.4 Å²	69.4	55%	0.552	36%	0.356	S	S	*	.	H	α-helix	trans	-62.8	-45.8	175.2	174.9	0	0	0	0	110.6	N148 K149 A150 I154 L155 M156	N148-V152 PolarHBondContact O-N 3.49Å; N148-V152 VanDerWaalsContact O-N 3.1Å; K149-V152 PolarHBondContact O-N 3.01Å; A150-V152 PolarHBondContact O-N 3.44Å; V152-I154 VanDerWaalsContact C-N 3.34Å; V152-I154 PolarHBondContact O-N 3.41Å; V152-L155 PolarHBondContact O-N 3.06Å; V152-M156 HydrophobicContact CG1-CG 4.45Å; V152-M156 WeakPolarHBondContact O-CG 3.4Å; V152-M156 PolarHBondContact O-N 3.01Å
153	I	97.7	Very high	95.1	Very high	61 Å²	61	66.6 Å²	66.6	31%	0.313	35%	0.345	S	S	.	.	H	α-helix	trans	-60.3	-44.6	177	-66.4	165.2	0	0	0	110.9	F71 V126 L145 K149 A150 M156 V157	F71-I153 HydrophobicContact CE1-CB 4.3Å; F71-I153 HydrophobicContact CE1-CG2 4Å; F71-I153 HydrophobicContact CZ-CG2 4.42Å; V126-I153 HydrophobicContact CG1-CG2 3.76Å; V126-I153 HydrophobicContact CG2-CG2 4.11Å; L145-I153 HydrophobicContact CD1-CD1 3.71Å; K149-I153 WeakPolarHBondContact O-CG1 3.31Å; K149-I153 PolarHBondContact O-N 3.29Å; A150-I153 PolarHBondContact O-N 3.46Å; I153-M156 PolarHBondContact O-N 3.46Å; I153-V157 WeakPolarHBondContact O-CG2 3.24Å; I153-V157 PolarHBondContact O-N 2.81Å
154	I	98.4	Very high	95.8	Very high	28 Å²	28	64.5 Å²	64.5	14%	0.144	33%	0.329	C	S	.	.	H	α-helix	trans	-57.9	-51.2	175.7	-70	164.3	0	0	0	110.1	Y70 F71 A150 R151 V152 M156 V157 W158	Y70-I154 WeakPolarHBondContact O-CD1 3.25Å; F71-I154 HydrophobicContact CD1-CD1 3.97Å; F71-I154 HydrophobicContact CD1-CG1 3.63Å; F71-I154 HydrophobicContact CE1-CD1 4.29Å; F71-I154 HydrophobicContact CE1-CG1 3.82Å; A150-I154 VanDerWaalsContact O-CG1 3.32Å; A150-I154 WeakPolarHBondContact O-CG1 3.21Å; A150-I154 PolarHBondContact O-N 2.94Å; R151-I154 PolarHBondContact O-N 3.06Å; V152-I154 VanDerWaalsContact C-N 3.34Å; V152-I154 PolarHBondContact O-N 3.41Å; I154-M156 VanDerWaalsContact C-N 3.26Å; I154-M156 PolarHBondContact O-N 3Å; I154-V157 WeakPolarHBondContact O-CB 3.35Å; I154-V157 PolarHBondContact O-N 3.5Å; I154-V157 VanDerWaalsContact O-N 3.08Å; I154-W158 VanDerWaalsContact O-CD1 3.25Å; I154-W158 PolarHBondContact O-N 3.49Å; I154-W158 VanDerWaalsContact O-N 3.07Å
155	L	98.3	Very high	96.4	Very high	107 Å²	107	60.3 Å²	60.3	56%	0.56	31%	0.307	S	S	*	.	H	α-helix	trans	-56.8	-41.6	178.7	-177.1	65.2	0	0	0	111.9	R151 V152 W158 I159	R151-L155 PolarHBondContact O-N 3.45Å; V152-L155 PolarHBondContact O-N 3.06Å; L155-W158 PolarHBondContact O-N 2.91Å; L155-I159 HydrophobicContact CD1-CD1 4.34Å; L155-I159 HydrophobicContact CG-CD1 3.93Å; L155-I159 VanDerWaalsContact O-CG1 3.31Å; L155-I159 WeakPolarHBondContact O-CG1 3.37Å; L155-I159 PolarHBondContact O-N 2.99Å
156	M	98.2	Very high	96.8	Very high	98 Å²	98	61.4 Å²	61.4	48%	0.483	31%	0.311	S	S	.	.	H	α-helix	trans	-63.6	-40.7	176.6	-68.7	-54.3	-59.1	0	0	112.5	V152 I153 I154 I159 V160	V152-M156 HydrophobicContact CG1-CG 4.45Å; V152-M156 WeakPolarHBondContact O-CG 3.4Å; V152-M156 PolarHBondContact O-N 3.01Å; I153-M156 PolarHBondContact O-N 3.46Å; I154-M156 VanDerWaalsContact C-N 3.26Å; I154-M156 PolarHBondContact O-N 3Å; M156-I159 PolarHBondContact O-N 3.48Å; M156-I159 HydrophobicContact SD-CD1 4.44Å; M156-V160 WeakPolarHBondContact O-CB 3.24Å; M156-V160 VanDerWaalsContact O-CG2 3.29Å; M156-V160 WeakPolarHBondContact O-CG2 2.96Å; M156-V160 PolarHBondContact O-N 2.98Å
157	V	98.3	Very high	97.1	Very high	14 Å²	14	61.9 Å²	61.9	9%	0.085	31%	0.311	C	S	.	.	H	α-helix	trans	-57.6	-49	173.7	166.7	0	0	0	0	110.5	E122 V126 I153 I154 I159 V160 S161	E122-V157 HydrophobicContact CB-CG1 3.74Å; V126-V157 HydrophobicContact CG2-CG2 3.97Å; I153-V157 WeakPolarHBondContact O-CG2 3.24Å; I153-V157 PolarHBondContact O-N 2.81Å; I154-V157 WeakPolarHBondContact O-CB 3.35Å; I154-V157 PolarHBondContact O-N 3.5Å; I154-V157 VanDerWaalsContact O-N 3.08Å; V157-I159 PolarHBondContact O-N 3.36Å; V157-V160 PolarHBondContact O-N 2.91Å; V157-S161 WeakPolarHBondContact O-CB 3.47Å; V157-S161 PolarHBondContact O-N 2.89Å; V157-S161 PolarHBondContact O-OG 3.48Å; V157-S161 VanDerWaalsContact O-OG 3.09Å
158	W	98.6	Very high	97.3	Very high	67 Å²	67	58.4 Å²	58.4	25%	0.254	30%	0.298	S	S	.	.	H	α-helix	trans	-65	-36.4	179.1	-76.2	86.5	0	0	0	113.1	S74 C77 A78 L115 I154 L155 G162	S74-W158 PolarHBondContact OG-NE1 3Å; C77-W158 HydrophobicContact CB-CH2 4.46Å; C77-W158 HydrophobicContact CB-CZ2 4.01Å; A78-W158 HydrophobicContact CB-CH2 4.14Å; A78-W158 HydrophobicContact CB-CZ2 4.22Å; L115-W158 HydrophobicContact CD1-CE3 4.27Å; L115-W158 HydrophobicContact CD2-CE3 4.45Å; L115-W158 HydrophobicContact CD2-CZ3 4.27Å; L115-W158 HydrophobicContact CG-CZ3 4.46Å; I154-W158 VanDerWaalsContact O-CD1 3.25Å; I154-W158 PolarHBondContact O-N 3.49Å; I154-W158 VanDerWaalsContact O-N 3.07Å; L155-W158 PolarHBondContact O-N 2.91Å; W158-G162 WeakPolarHBondContact O-CA 3.49Å; W158-G162 PolarHBondContact O-N 3.36Å
159	I	98.3	Very high	97.4	Very high	78 Å²	78	53.4 Å²	53.4	40%	0.4	27%	0.271	S	S	.	.	H	α-helix	trans	-66.4	-49	175.2	-70	167.7	0	0	0	110.7	L155 M156 V157 G162 L163	L155-I159 HydrophobicContact CD1-CD1 4.34Å; L155-I159 HydrophobicContact CG-CD1 3.93Å; L155-I159 VanDerWaalsContact O-CG1 3.31Å; L155-I159 WeakPolarHBondContact O-CG1 3.37Å; L155-I159 PolarHBondContact O-N 2.99Å; M156-I159 PolarHBondContact O-N 3.48Å; M156-I159 HydrophobicContact SD-CD1 4.44Å; V157-I159 PolarHBondContact O-N 3.36Å; I159-G162 PolarHBondContact O-N 3.49Å; I159-L163 HydrophobicContact CG2-CD1 3.95Å; I159-L163 HydrophobicContact CG2-CG 4.43Å; I159-L163 WeakPolarHBondContact O-CB 3.29Å; I159-L163 VanDerWaalsContact O-CG 3.3Å; I159-L163 WeakPolarHBondContact O-CG 3.42Å; I159-L163 PolarHBondContact O-N 2.87Å
160	V	97.3	Very high	97.5	Very high	60 Å²	60	51.9 Å²	51.9	36%	0.364	27%	0.265	S	S	.	.	H	α-helix	trans	-62.7	-51.4	-179.6	172.1	0	0	0	0	110.1	M156 V157 G162 L163 T164	M156-V160 WeakPolarHBondContact O-CB 3.24Å; M156-V160 VanDerWaalsContact O-CG2 3.29Å; M156-V160 WeakPolarHBondContact O-CG2 2.96Å; M156-V160 PolarHBondContact O-N 2.98Å; V157-V160 PolarHBondContact O-N 2.91Å; V160-G162 VanDerWaalsContact C-N 3.27Å; V160-G162 PolarHBondContact O-N 3.38Å; V160-L163 PolarHBondContact O-N 2.79Å; V160-L163 VanDerWaalsContact O-N 3.15Å; V160-T164 HydrophobicContact CG1-CG2 4.5Å; V160-T164 WeakPolarHBondContact O-CG2 3.34Å; V160-T164 PolarHBondContact O-N 2.84Å; V160-T164 PolarHBondContact O-OG1 3.01Å
161	S	98	Very high	97.6	Very high	0 Å²	0	57.4 Å²	57.4	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-57.8	-39.1	175.4	-68.5	0	0	0	0	112.1	A119 E122 V157 T164 S165	A119-S161 VanDerWaalsContact CA-OG 3.22Å; A119-S161 WeakPolarHBondContact CA-OG 3.46Å; A119-S161 PolarHBondContact N-OG 2.87Å; E122-S161 VanDerWaalsContact CD-OG 3.28Å; E122-S161 PolarHBondContact OE2-OG 3.46Å; V157-S161 WeakPolarHBondContact O-CB 3.47Å; V157-S161 PolarHBondContact O-N 2.89Å; V157-S161 PolarHBondContact O-OG 3.48Å; V157-S161 VanDerWaalsContact O-OG 3.09Å; S161-T164 WeakPolarHBondContact CA-OG1 3.43Å; S161-T164 PolarHBondContact O-OG1 3.36Å; S161-T164 VanDerWaalsContact O-OG1 3.07Å; S161-S165 WeakPolarHBondContact O-CB 3.42Å; S161-S165 PolarHBondContact O-N 2.91Å; S161-S165 PolarHBondContact O-OG 3.05Å
162	G	97.9	Very high	97.6	Very high	17 Å²	17	55.2 Å²	55.2	18%	0.175	29%	0.288	C	S	.	.	H	α-helix	trans	-63.8	-46.1	175.2	0	0	0	0	0	112.5	W158 I159 V160 S165 F166	W158-G162 WeakPolarHBondContact O-CA 3.49Å; W158-G162 PolarHBondContact O-N 3.36Å; I159-G162 PolarHBondContact O-N 3.49Å; V160-G162 VanDerWaalsContact C-N 3.27Å; V160-G162 PolarHBondContact O-N 3.38Å; G162-S165 PolarHBondContact O-N 3.27Å; G162-F166 WeakPolarHBondContact O-CB 3.45Å; G162-F166 PolarHBondContact O-N 3.24Å
163	L	96.7	Very high	97.5	Very high	100 Å²	100	58.3 Å²	58.3	52%	0.524	29%	0.289	S	S	.	.	H	α-helix	trans	-64.2	-42.3	177.5	-72.3	171.3	0	0	0	112	I159 V160 S165 L167	I159-L163 HydrophobicContact CG2-CD1 3.95Å; I159-L163 HydrophobicContact CG2-CG 4.43Å; I159-L163 WeakPolarHBondContact O-CB 3.29Å; I159-L163 VanDerWaalsContact O-CG 3.3Å; I159-L163 WeakPolarHBondContact O-CG 3.42Å; I159-L163 PolarHBondContact O-N 2.87Å; V160-L163 PolarHBondContact O-N 2.79Å; V160-L163 VanDerWaalsContact O-N 3.15Å; L163-S165 VanDerWaalsContact C-N 3.28Å; L163-S165 PolarHBondContact O-N 3.47Å; L163-L167 HydrophobicContact CD2-CD1 4.48Å; L163-L167 WeakPolarHBondContact O-CB 3.46Å; L163-L167 PolarHBondContact O-N 3.49Å
164	T	95.5	Very high	97.5	Very high	35 Å²	35	55.8 Å²	55.8	22%	0.215	28%	0.276	C	S	.	.	H	α-helix	trans	-71.7	-23.5	179.2	56.3	0	0	0	0	113.1	V160 S161 P168 V206	V160-T164 HydrophobicContact CG1-CG2 4.5Å; V160-T164 WeakPolarHBondContact O-CG2 3.34Å; V160-T164 PolarHBondContact O-N 2.84Å; V160-T164 PolarHBondContact O-OG1 3.01Å; S161-T164 WeakPolarHBondContact CA-OG1 3.43Å; S161-T164 PolarHBondContact O-OG1 3.36Å; S161-T164 VanDerWaalsContact O-OG1 3.07Å; T164-P168 WeakPolarHBondContact O-CD 3.31Å; T164-P168 WeakPolarHBondContact O-CG 3.2Å; T164-V206 HydrophobicContact CG2-CG1 4.15Å
165	S	97.1	Very high	97.4	Very high	0 Å²	0	58.3 Å²	58.3	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-97.1	-58	-176.5	-49.6	0	0	0	0	112.1	V114 L115 S161 G162 L163 I169	V114-S165 PolarHBondContact O-OG 3.45Å; L115-S165 VanDerWaalsContact CA-OG 3.29Å; L115-S165 WeakPolarHBondContact CA-OG 3.26Å; L115-S165 PolarHBondContact N-OG 3.18Å; S161-S165 WeakPolarHBondContact O-CB 3.42Å; S161-S165 PolarHBondContact O-N 2.91Å; S161-S165 PolarHBondContact O-OG 3.05Å; G162-S165 PolarHBondContact O-N 3.27Å; L163-S165 VanDerWaalsContact C-N 3.28Å; L163-S165 PolarHBondContact O-N 3.47Å; S165-I169 WeakPolarHBondContact O-CD1 3.19Å; S165-I169 WeakPolarHBondContact O-CG1 3.45Å
166	F	97.9	Very high	97.2	Very high	52 Å²	52	53.6 Å²	53.6	23%	0.228	26%	0.26	C	S	.	.	H	α-helix	trans	-70.8	-43.9	-176	-80.7	-102.8	0	0	0	112	F108 I112 L115 G162 I169 Q170	F108-F166 HydrophobicContact CD2-CE1 4.01Å; F108-F166 AromaticContact CE2-CE1 3.77Å; F108-F166 HydrophobicContact CE2-CE1 3.77Å; F108-F166 HydrophobicContact CE2-CZ 4.43Å; F108-F166 HydrophobicContact CZ-CE1 4.44Å; I112-F166 HydrophobicContact CG1-CZ 4.02Å; L115-F166 HydrophobicContact CB-CE2 4.03Å; L115-F166 HydrophobicContact CD2-CE2 3.7Å; L115-F166 HydrophobicContact CG-CE2 4.42Å; G162-F166 WeakPolarHBondContact O-CB 3.45Å; G162-F166 PolarHBondContact O-N 3.24Å; F166-I169 PolarHBondContact O-N 3.28Å; F166-Q170 HydrophobicContact CB-CG 4.37Å; F166-Q170 HydrophobicContact CD1-CG 4.23Å; F166-Q170 VanDerWaalsContact O-CB 3.3Å; F166-Q170 WeakPolarHBondContact O-CB 3.29Å; F166-Q170 WeakPolarHBondContact O-CG 3.13Å; F166-Q170 PolarHBondContact O-N 3.42Å
167	L	97.1	Very high	97.1	Very high	69 Å²	69	55.1 Å²	55.1	36%	0.361	28%	0.275	S	S	.	.	H	α-helix	trans	-60	-52	-171.9	-166.6	166	0	0	0	111.9	L163 I169 M171 W173	L163-L167 HydrophobicContact CD2-CD1 4.48Å; L163-L167 WeakPolarHBondContact O-CB 3.46Å; L163-L167 PolarHBondContact O-N 3.49Å; L167-I169 VanDerWaalsContact C-N 3.3Å; L167-I169 PolarHBondContact O-N 3.44Å; L167-M171 HydrophobicContact CD2-CG 4.09Å; L167-M171 HydrophobicContact CG-CG 4.46Å; L167-M171 WeakPolarHBondContact O-CB 3.3Å; L167-M171 WeakPolarHBondContact O-CG 3.36Å; L167-M171 PolarHBondContact O-N 2.88Å; L167-W173 HydrophobicContact CD2-CD2 4.43Å; L167-W173 HydrophobicContact CD2-CE3 3.87Å; L167-W173 HydrophobicContact CD2-CH2 3.35Å; L167-W173 HydrophobicContact CD2-CZ2 3.95Å; L167-W173 HydrophobicContact CD2-CZ3 3.3Å
168	P	97.1	Very high	96.8	Very high	19 Å²	19	58.3 Å²	58.3	12%	0.123	29%	0.289	C	S	.	.	H	α-helix	trans	-66	-30.5	-179.5	-23.2	36.5	0	0	0	114	T164 H172 W173 Y174 Y199	T164-P168 WeakPolarHBondContact O-CD 3.31Å; T164-P168 WeakPolarHBondContact O-CG 3.2Å; P168-H172 PolarHBondContact O-N 3.29Å; P168-W173 HydrophobicContact CB-CB 4.36Å; P168-W173 HydrophobicContact CB-CE3 4.42Å; P168-W173 PolarHBondContact O-N 3.19Å; P168-Y174 PolarHBondContact O-N 3.19Å; P168-Y199 HydrophobicContact CB-CD2 3.88Å; P168-Y199 HydrophobicContact CB-CE2 3.45Å; P168-Y199 VanDerWaalsContact CB-CE2 3.45Å; P168-Y199 HydrophobicContact CG-CE2 4.13Å
169	I	97.3	Very high	96.7	Very high	0 Å²	0	61 Å²	61	0%	0	30%	0.304	C	S	.	.	H	α-helix	trans	-77.2	-50.8	-177.8	-64.9	170.5	0	0	0	110.4	E107 T110 S111 V114 S165 F166 L167 M171 H172 Y174	E107-I169 HydrophobicContact CB-CG2 4.29Å; T110-I169 HydrophobicContact CG2-CD1 3.95Å; S111-I169 VanDerWaalsContact OG-CG2 3.32Å; S111-I169 WeakPolarHBondContact OG-CG2 3.42Å; V114-I169 HydrophobicContact CB-CD1 4.46Å; V114-I169 HydrophobicContact CG2-CD1 4.13Å; S165-I169 WeakPolarHBondContact O-CD1 3.19Å; S165-I169 WeakPolarHBondContact O-CG1 3.45Å; F166-I169 PolarHBondContact O-N 3.28Å; L167-I169 VanDerWaalsContact C-N 3.3Å; L167-I169 PolarHBondContact O-N 3.44Å; I169-M171 VanDerWaalsContact C-N 3.31Å; I169-M171 PolarHBondContact O-N 3.01Å; I169-H172 WeakPolarHBondContact O-CA 3.35Å; I169-H172 PolarHBondContact O-N 3.5Å; I169-H172 PolarHBondContact O-ND1 3.46Å; I169-Y174 HydrophobicContact CB-CD1 4.32Å; I169-Y174 HydrophobicContact CB-CE1 4.42Å; I169-Y174 HydrophobicContact CG1-CD1 4.31Å; I169-Y174 HydrophobicContact CG2-CD1 4.33Å; I169-Y174 HydrophobicContact CG2-CE1 3.95Å; I169-Y174 WeakPolarHBondContact O-CE1 3.15Å
170	Q	97	Very high	96.5	Very high	70 Å²	70	63.6 Å²	63.6	33%	0.327	31%	0.314	S	S	.	.	H	α-helix	trans	-69.7	-28.1	-178.4	-57.5	-59	-37.9	0	0	112.4	E107 S111 F166 H172	E107-Q170 PolarHBondContact O-NE2 2.71Å; S111-Q170 PolarHBondContact OG-NE2 3.28Å; F166-Q170 HydrophobicContact CB-CG 4.37Å; F166-Q170 HydrophobicContact CD1-CG 4.23Å; F166-Q170 VanDerWaalsContact O-CB 3.3Å; F166-Q170 WeakPolarHBondContact O-CB 3.29Å; F166-Q170 WeakPolarHBondContact O-CG 3.13Å; F166-Q170 PolarHBondContact O-N 3.42Å; Q170-H172 VanDerWaalsContact C-N 3.27Å
171	M	97	Very high	96.3	Very high	115 Å²	115	60.7 Å²	60.7	57%	0.567	30%	0.297	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.8	3.6	171.7	-61.3	-61.2	-63.6	0	0	113.3	L167 I169 W173	L167-M171 HydrophobicContact CD2-CG 4.09Å; L167-M171 HydrophobicContact CG-CG 4.46Å; L167-M171 WeakPolarHBondContact O-CB 3.3Å; L167-M171 WeakPolarHBondContact O-CG 3.36Å; L167-M171 PolarHBondContact O-N 2.88Å; I169-M171 VanDerWaalsContact C-N 3.31Å; I169-M171 PolarHBondContact O-N 3.01Å; M171-W173 HydrophobicContact CB-CD2 4.21Å; M171-W173 HydrophobicContact CB-CG 4.16Å; M171-W173 HydrophobicContact CB-CZ2 4.46Å; M171-W173 VanDerWaalsContact O-CD1 3.23Å; M171-W173 PolarHBondContact O-N 3.18Å; M171-W173 VanDerWaalsContact O-N 3.16Å
172	H	97.1	Very high	96.3	Very high	79 Å²	79	64.4 Å²	64.4	37%	0.366	32%	0.316	S	S	.	.	T	Hydrogen-bonded Turn	trans	58.7	20.6	-179.5	-50.3	-43.6	0	0	0	115.7	E107 P168 I169 Q170 Y174 R175	E107-H172 IonicContact OE1-CE1 3.24Å; E107-H172 PolarHBondContact OE1-CE1 3.26Å; E107-H172 IonicContact OE1-ND1 3.67Å; E107-H172 PolarHBondContact OE1-ND1 3Å; E107-H172 IonicContact OE2-CE1 3.63Å; E107-H172 PolarHBondContact OE2-CE1 2.94Å; E107-H172 VanDerWaalsContact OE2-CE1 3.24Å; E107-H172 IonicContact OE2-ND1 2.95Å; P168-H172 PolarHBondContact O-N 3.29Å; I169-H172 WeakPolarHBondContact O-CA 3.35Å; I169-H172 PolarHBondContact O-N 3.5Å; I169-H172 PolarHBondContact O-ND1 3.46Å; Q170-H172 VanDerWaalsContact C-N 3.27Å; H172-Y174 PolarHBondContact O-N 2.98Å; H172-R175 HydrophobicContact CB-CG 4.15Å; H172-R175 PolarHBondContact CE1-NH2 2.88Å; H172-R175 PolarHBondContact ND1-NH2 2.96Å; H172-R175 VanDerWaalsContact ND1-NH2 3.17Å; H172-R175 PolarHBondContact O-N 3.43Å
173	W	97.2	Very high	96.3	Very high	156 Å²	156	68 Å²	68	59%	0.591	33%	0.332	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.6	-18.8	178	-64	-5.9	0	0	0	113.2	L167 P168 M171 N196	L167-W173 HydrophobicContact CD2-CD2 4.43Å; L167-W173 HydrophobicContact CD2-CE3 3.87Å; L167-W173 HydrophobicContact CD2-CH2 3.35Å; L167-W173 HydrophobicContact CD2-CZ2 3.95Å; L167-W173 HydrophobicContact CD2-CZ3 3.3Å; P168-W173 HydrophobicContact CB-CB 4.36Å; P168-W173 HydrophobicContact CB-CE3 4.42Å; P168-W173 PolarHBondContact O-N 3.19Å; M171-W173 HydrophobicContact CB-CD2 4.21Å; M171-W173 HydrophobicContact CB-CG 4.16Å; M171-W173 HydrophobicContact CB-CZ2 4.46Å; M171-W173 VanDerWaalsContact O-CD1 3.23Å; M171-W173 PolarHBondContact O-N 3.18Å; M171-W173 VanDerWaalsContact O-N 3.16Å; W173-N196 PolarHBondContact O-ND2 3.35Å
174	Y	96.7	Very high	96.3	Very high	8 Å²	8	63.7 Å²	63.7	3%	0.031	31%	0.309	C	S	.	.	T	Hydrogen-bonded Turn	trans	-76.7	-24.3	177.6	78.3	-79.6	0	0	0	113.5	E107 P168 I169 H172 A176 Y185 F193 T195 N196	E107-Y174 PolarHBondContact OE1-OH 3.32Å; P168-Y174 PolarHBondContact O-N 3.19Å; I169-Y174 HydrophobicContact CB-CD1 4.32Å; I169-Y174 HydrophobicContact CB-CE1 4.42Å; I169-Y174 HydrophobicContact CG1-CD1 4.31Å; I169-Y174 HydrophobicContact CG2-CD1 4.33Å; I169-Y174 HydrophobicContact CG2-CE1 3.95Å; I169-Y174 WeakPolarHBondContact O-CE1 3.15Å; H172-Y174 PolarHBondContact O-N 2.98Å; Y174-A176 PolarHBondContact O-N 3.46Å; Y174-Y185 HydrophobicContact CE2-CE1 4.26Å; Y174-F193 AromaticContact CD2-CD2 3.98Å; Y174-F193 HydrophobicContact CD2-CD2 3.98Å; Y174-F193 AromaticContact CD2-CE2 3.51Å; Y174-F193 HydrophobicContact CD2-CE2 3.51Å; Y174-F193 HydrophobicContact CD2-CZ 4.34Å; Y174-F193 AromaticContact CE2-CD2 3.91Å; Y174-F193 HydrophobicContact CE2-CD2 3.91Å; Y174-F193 AromaticContact CE2-CE2 3.8Å; Y174-F193 HydrophobicContact CE2-CE2 3.8Å; Y174-F193 HydrophobicContact CG-CE2 4.15Å; Y174-T195 HydrophobicContact CD2-CG2 4.08Å; Y174-T195 CarbonylContact O-C 3.43Å; Y174-T195 WeakPolarHBondContact O-CA 3.34Å; Y174-N196 VanDerWaalsContact C-ND2 3.26Å; Y174-N196 PolarHBondContact O-N 3.26Å; Y174-N196 PolarHBondContact O-ND2 2.92Å; Y174-N196 VanDerWaalsContact O-ND2 3.1Å
175	R	96.7	Very high	96.3	Very high	81 Å²	81	63.6 Å²	63.6	31%	0.306	31%	0.305	S	S	.	.	B	Isolated β-bridge	trans	-62	132.3	-165.2	-69	-171.3	-178.6	174	0	112.6	E107 H172 Y185 N196	E107-R175 IonicContact OE1-CZ 2.66Å; E107-R175 IonicContact OE1-NE 4Å; E107-R175 IonicContact OE1-NH2 2.84Å; E107-R175 PolarHBondContact OE1-NH2 3.34Å; H172-R175 HydrophobicContact CB-CG 4.15Å; H172-R175 PolarHBondContact CE1-NH2 2.88Å; H172-R175 PolarHBondContact ND1-NH2 2.96Å; H172-R175 VanDerWaalsContact ND1-NH2 3.17Å; H172-R175 PolarHBondContact O-N 3.43Å; R175-Y185 WeakPolarHBondContact CA-OH 3.3Å; R175-Y185 HydrophobicContact CB-CD2 4.47Å; R175-Y185 HydrophobicContact CB-CE2 3.75Å; R175-Y185 HydrophobicContact CG-CD2 4.29Å; R175-Y185 HydrophobicContact CG-CE1 4.18Å; R175-Y185 HydrophobicContact CG-CE2 3.91Å; R175-N196 PolarHBondContact O-ND2 3.01Å; R175-N196 VanDerWaalsContact O-ND2 3.12Å
176	A	95	Very high	96.2	Very high	7 Å²	7	67.4 Å²	67.4	6%	0.058	34%	0.337	C	S	.	.			trans	-73.2	156.3	168.4	0	0	0	0	0	112.5	Y174 A181 Y185 F194	Y174-A176 PolarHBondContact O-N 3.46Å; A176-A181 HydrophobicContact CB-CB 3.9Å; A176-Y185 PolarHBondContact N-OH 3.49Å; A176-F194 HydrophobicContact CB-CB 4.24Å
177	T	94.9	Very high	96.1	Very high	130 Å²	130	68.5 Å²	68.5	80%	0.798	35%	0.345	S	S	*	.			trans	-106.2	-0.1	-173.2	54.2	0	0	0	0	115
178	H	93	Very high	96.1	Very high	81 Å²	81	71.4 Å²	71.4	38%	0.375	36%	0.357	S	S	.	.	S	Bend	trans	-80.4	155.1	178.1	62	-93.7	0	0	0	111.4	E180 A181 I182 F194	H178-E180 PolarHBondContact O-N 2.86Å; H178-A181 PolarHBondContact CD2-N 2.96Å; H178-A181 WeakPolarHBondContact NE2-CB 3.36Å; H178-A181 PolarHBondContact NE2-N 3Å; H178-A181 PolarHBondContact O-N 2.94Å; H178-I182 WeakPolarHBondContact O-CG1 3.29Å; H178-I182 PolarHBondContact O-N 3.45Å; H178-I182 VanDerWaalsContact O-N 3.16Å; H178-F194 AromaticContact NE2-CD1 3.76Å
179	Q	95.4	Very high	96.1	Very high	125 Å²	125	73.1 Å²	73.1	58%	0.584	37%	0.367	S	S	*	.	H	α-helix	trans	-61.2	-38	-167.1	-169.3	62.9	48.2	0	0	114	I182 N183	Q179-I182 PolarHBondContact O-N 2.97Å; Q179-N183 PolarHBondContact NE2-OD1 3.41Å; Q179-N183 WeakPolarHBondContact O-CB 3.44Å; Q179-N183 PolarHBondContact O-N 3.31Å; Q179-N183 PolarHBondContact O-ND2 3.47Å; Q179-N183 PolarHBondContact O-OD1 3.39Å
180	E	93.7	Very high	96	Very high	131 Å²	131	74.4 Å²	74.4	61%	0.612	38%	0.376	S	S	*	.	H	α-helix	trans	-59.9	-47.3	178.5	-174	177	-174.4	0	0	111.7	H178 I182 N183 C184 F194	H178-E180 PolarHBondContact O-N 2.86Å; E180-I182 PolarHBondContact O-N 3.1Å; E180-N183 PolarHBondContact O-N 2.66Å; E180-C184 PolarHBondContact O-N 3.16Å; E180-F194 HydrophobicContact CG-CZ 4.25Å
181	A	94.9	Very high	96	Very high	0 Å²	0	71.3 Å²	71.3	0%	0	36%	0.362	C	S	.	.	H	α-helix	trans	-61	-44.5	174.3	0	0	0	0	0	112.7	A176 H178 N183 C184 Y185 F194	A176-A181 HydrophobicContact CB-CB 3.9Å; H178-A181 PolarHBondContact CD2-N 2.96Å; H178-A181 WeakPolarHBondContact NE2-CB 3.36Å; H178-A181 PolarHBondContact NE2-N 3Å; H178-A181 PolarHBondContact O-N 2.94Å; A181-N183 VanDerWaalsContact C-N 3.3Å; A181-N183 PolarHBondContact O-N 3.27Å; A181-C184 WeakPolarHBondContact O-CB 3.37Å; A181-C184 PolarHBondContact O-N 3.16Å; A181-C184 VanDerWaalsContact O-N 3.13Å; A181-Y185 HydrophobicContact CB-CE2 3.82Å; A181-Y185 WeakPolarHBondContact O-CD2 3.49Å; A181-Y185 WeakPolarHBondContact O-CE2 3.45Å; A181-Y185 VanDerWaalsContact O-CG 3.24Å; A181-Y185 PolarHBondContact O-N 3.35Å; A181-F194 HydrophobicContact CB-CB 3.59Å; A181-F194 HydrophobicContact CB-CD1 4.36Å; A181-F194 HydrophobicContact CB-CD2 4.1Å; A181-F194 HydrophobicContact CB-CG 3.78Å
182	I	96.8	Very high	95.9	Very high	78 Å²	78	67.9 Å²	67.9	40%	0.4	35%	0.346	S	S	.	.	H	α-helix	trans	-59.7	-43.4	178.2	-62.8	175.3	0	0	0	110.8	H178 Q179 E180 C184 Y185 A186	H178-I182 WeakPolarHBondContact O-CG1 3.29Å; H178-I182 PolarHBondContact O-N 3.45Å; H178-I182 VanDerWaalsContact O-N 3.16Å; Q179-I182 PolarHBondContact O-N 2.97Å; E180-I182 PolarHBondContact O-N 3.1Å; I182-C184 VanDerWaalsContact C-N 3.32Å; I182-C184 PolarHBondContact O-N 3.01Å; I182-Y185 PolarHBondContact O-N 2.95Å; I182-A186 PolarHBondContact O-N 3.47Å
183	N	97.3	Very high	95.7	Very high	93 Å²	93	67.2 Å²	67.2	50%	0.497	34%	0.342	S	S	.	.	H	α-helix	trans	-62.9	-39.3	176.6	-66.7	-11.2	0	0	0	111.5	Q179 E180 A181 N187	Q179-N183 PolarHBondContact NE2-OD1 3.41Å; Q179-N183 WeakPolarHBondContact O-CB 3.44Å; Q179-N183 PolarHBondContact O-N 3.31Å; Q179-N183 PolarHBondContact O-ND2 3.47Å; Q179-N183 PolarHBondContact O-OD1 3.39Å; E180-N183 PolarHBondContact O-N 2.66Å; A181-N183 VanDerWaalsContact C-N 3.3Å; A181-N183 PolarHBondContact O-N 3.27Å; N183-N187 WeakPolarHBondContact O-CB 3.18Å; N183-N187 PolarHBondContact O-N 3.28Å
184	C	96.5	Very high	95.5	Very high	8 Å²	8	61.8 Å²	61.8	5%	0.054	32%	0.323	C	S	.	.	H	α-helix	trans	-63.3	-50.4	175.5	-177.7	0	0	0	0	111.7	E180 A181 I182 A186 N187 C190 F194	E180-C184 PolarHBondContact O-N 3.16Å; A181-C184 WeakPolarHBondContact O-CB 3.37Å; A181-C184 PolarHBondContact O-N 3.16Å; A181-C184 VanDerWaalsContact O-N 3.13Å; I182-C184 VanDerWaalsContact C-N 3.32Å; I182-C184 PolarHBondContact O-N 3.01Å; C184-A186 PolarHBondContact O-N 3.19Å; C184-N187 PolarHBondContact O-N 3.13Å; C184-C190 VanDerWaalsContact CA-SG 3.59Å; C184-C190 HydrophobicContact CB-CB 3.95Å; C184-C190 WeakPolarHBondContact CB-SG 3.34Å; C184-C190 WeakPolarHBondContact SG-CB 3.23Å; C184-C190 CovalentContact SG-SG 2.04Å; C184-C190 PolarHBondContact SG-SG 3.24Å; C184-F194 HydrophobicContact CB-CD2 4.09Å; C184-F194 HydrophobicContact CB-CE2 3.95Å
185	Y	96.1	Very high	95.4	Very high	33 Å²	33	63 Å²	63	13%	0.129	33%	0.33	C	S	.	.	H	α-helix	trans	-61	-30.3	-179.3	-51.8	-44.7	0	0	0	113.4	N103 Y174 R175 A176 A181 I182 F194	N103-Y185 PolarHBondContact ND2-O 3.31Å; N103-Y185 VanDerWaalsContact ND2-O 3.14Å; Y174-Y185 HydrophobicContact CE2-CE1 4.26Å; R175-Y185 WeakPolarHBondContact CA-OH 3.3Å; R175-Y185 HydrophobicContact CB-CD2 4.47Å; R175-Y185 HydrophobicContact CB-CE2 3.75Å; R175-Y185 HydrophobicContact CG-CD2 4.29Å; R175-Y185 HydrophobicContact CG-CE1 4.18Å; R175-Y185 HydrophobicContact CG-CE2 3.91Å; A176-Y185 PolarHBondContact N-OH 3.49Å; A181-Y185 HydrophobicContact CB-CE2 3.82Å; A181-Y185 WeakPolarHBondContact O-CD2 3.49Å; A181-Y185 WeakPolarHBondContact O-CE2 3.45Å; A181-Y185 VanDerWaalsContact O-CG 3.24Å; A181-Y185 PolarHBondContact O-N 3.35Å; I182-Y185 PolarHBondContact O-N 2.95Å; Y185-F194 HydrophobicContact CE1-CB 4.32Å; Y185-F194 VanDerWaalsContact OH-CB 3.31Å; Y185-F194 WeakPolarHBondContact OH-CB 3.3Å; Y185-F194 PolarHBondContact OH-O 3.23Å
186	A	96.1	Very high	95.2	Very high	81 Å²	81	61.1 Å²	61.1	67%	0.669	33%	0.327	S	S	*	.	H	α-helix	trans	-78.6	-21.7	177.4	0	0	0	0	0	113.1	I182 C184	I182-A186 PolarHBondContact O-N 3.47Å; C184-A186 PolarHBondContact O-N 3.19Å
187	N	96	Very high	95.2	Very high	74 Å²	74	66.9 Å²	66.9	40%	0.396	35%	0.353	S	S	.	.			trans	-94.6	114.4	-176.9	-179.4	5.4	0	0	0	110.9	N183 C184 T189 C190	N183-N187 WeakPolarHBondContact O-CB 3.18Å; N183-N187 PolarHBondContact O-N 3.28Å; C184-N187 PolarHBondContact O-N 3.13Å; N187-T189 PolarHBondContact ND2-OG1 3.4Å; N187-T189 PolarHBondContact O-N 3.11Å; N187-T189 PolarHBondContact OD1-N 2.96Å; N187-T189 PolarHBondContact OD1-OG1 3.42Å; N187-C190 HydrophobicContact CB-CB 4.19Å; N187-C190 PolarHBondContact O-N 2.97Å
188	E	95.7	Very high	95.2	Very high	130 Å²	130	64.1 Å²	64.1	61%	0.607	34%	0.343	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.1	-15.4	178.9	-64.7	-173.8	171.1	0	0	114.7	N103	N103-E188 WeakPolarHBondContact OD1-CA 3.45Å
189	T	96.9	Very high	95.3	Very high	56 Å²	56	61.2 Å²	61.2	34%	0.344	33%	0.328	S	S	.	.	T	Hydrogen-bonded Turn	trans	-94.6	0.8	177.8	66.1	0	0	0	0	114.5	M98 W99 N187	M98-T189 HydrophobicContact CE-CG2 3.39Å; W99-T189 WeakPolarHBondContact CB-O 3.49Å; W99-T189 PolarHBondContact N-O 2.95Å; W99-T189 WeakPolarHBondContact O-CA 3.48Å; N187-T189 PolarHBondContact ND2-OG1 3.4Å; N187-T189 PolarHBondContact O-N 3.11Å; N187-T189 PolarHBondContact OD1-N 2.96Å; N187-T189 PolarHBondContact OD1-OG1 3.42Å
190	C	96.6	Very high	95.2	Very high	26 Å²	26	55.3 Å²	55.3	18%	0.176	30%	0.301	C	S	.	.			trans	-113.3	128.4	178.3	-168.2	0	0	0	0	110.9	C184 N187	C184-C190 VanDerWaalsContact CA-SG 3.59Å; C184-C190 HydrophobicContact CB-CB 3.95Å; C184-C190 WeakPolarHBondContact CB-SG 3.34Å; C184-C190 WeakPolarHBondContact SG-CB 3.23Å; C184-C190 CovalentContact SG-SG 2.04Å; C184-C190 PolarHBondContact SG-SG 3.24Å; N187-C190 HydrophobicContact CB-CB 4.19Å; N187-C190 PolarHBondContact O-N 2.97Å
191	C	96.8	Very high	95.3	Very high	6 Å²	6	52.5 Å²	52.5	4%	0.041	29%	0.29	C	S	.	.			trans	-135.8	44.5	175.2	-170.3	0	0	0	0	110.5	W99 C106	W99-C191 HydrophobicContact CB-CB 3.74Å; W99-C191 HydrophobicContact CD2-CB 3.54Å; W99-C191 HydrophobicContact CE3-CB 3.87Å; W99-C191 HydrophobicContact CG-CB 3.5Å; W99-C191 VanDerWaalsContact CG-CB 3.5Å; C106-C191 VanDerWaalsContact CA-SG 3.5Å; C106-C191 HydrophobicContact CB-CB 3.85Å; C106-C191 WeakPolarHBondContact CB-SG 3.48Å; C106-C191 WeakPolarHBondContact SG-CA 3.32Å; C106-C191 WeakPolarHBondContact SG-CB 3.44Å; C106-C191 CovalentContact SG-SG 2.03Å; C106-C191 PolarHBondContact SG-SG 3.15Å
192	D	93.8	Very high	95.3	Very high	42 Å²	42	55 Å²	55	23%	0.225	31%	0.311	C	S	.	.			trans	-81.5	132.4	173.2	-78.3	-20.6	0	0	0	109.8	H93 F194 K305	H93-D192 IonicContact CE1-OD1 3.05Å; D192-F194 VanDerWaalsContact C-N 3.26Å; D192-F194 HydrophobicContact CB-CD2 3.77Å; D192-F194 HydrophobicContact CB-CE2 3.39Å; D192-F194 HydrophobicContact CB-CZ 4.11Å; D192-F194 PolarHBondContact O-N 3.32Å; D192-K305 IonicContact OD1-NZ 3.58Å; D192-K305 PolarHBondContact OD1-NZ 2.77Å; D192-K305 IonicContact OD2-NZ 3.13Å; D192-K305 PolarHBondContact OD2-NZ 3.49Å
193	F	93.3	Very high	95.2	Very high	66 Å²	66	52.3 Å²	52.3	29%	0.289	30%	0.299	S	S	.	.			trans	-82.9	67.2	-175.4	-169.8	-126.5	0	0	0	112.4	T110 Y174 T195 Y199	T110-F193 HydrophobicContact CG2-CD2 3.43Å; T110-F193 VanDerWaalsContact CG2-CD2 3.43Å; T110-F193 HydrophobicContact CG2-CE2 3.37Å; T110-F193 HydrophobicContact CG2-CG 4.18Å; T110-F193 HydrophobicContact CG2-CZ 4.04Å; Y174-F193 AromaticContact CD2-CD2 3.98Å; Y174-F193 HydrophobicContact CD2-CD2 3.98Å; Y174-F193 AromaticContact CD2-CE2 3.51Å; Y174-F193 HydrophobicContact CD2-CE2 3.51Å; Y174-F193 HydrophobicContact CD2-CZ 4.34Å; Y174-F193 AromaticContact CE2-CD2 3.91Å; Y174-F193 HydrophobicContact CE2-CD2 3.91Å; Y174-F193 AromaticContact CE2-CE2 3.8Å; Y174-F193 HydrophobicContact CE2-CE2 3.8Å; Y174-F193 HydrophobicContact CG-CE2 4.15Å; F193-T195 HydrophobicContact CD1-CG2 3.77Å; F193-T195 HydrophobicContact CD2-CG2 4.19Å; F193-T195 HydrophobicContact CE1-CG2 3.45Å; F193-T195 VanDerWaalsContact CE1-CG2 3.45Å; F193-T195 HydrophobicContact CE2-CG2 3.89Å; F193-T195 HydrophobicContact CG-CG2 4.16Å; F193-T195 HydrophobicContact CZ-CG2 3.54Å; F193-T195 PolarHBondContact O-N 2.98Å; F193-Y199 HydrophobicContact CE1-CE1 4.13Å; F193-Y199 AromaticContact CZ-CE1 3.58Å; F193-Y199 HydrophobicContact CZ-CE1 3.58Å
194	F	93	Very high	95.2	Very high	42 Å²	42	48 Å²	48	18%	0.184	28%	0.276	C	S	.	.			trans	-71.1	124.6	172.8	-67.5	-75.1	0	0	0	110.1	A176 H178 E180 A181 C184 Y185 D192	A176-F194 HydrophobicContact CB-CB 4.24Å; H178-F194 AromaticContact NE2-CD1 3.76Å; E180-F194 HydrophobicContact CG-CZ 4.25Å; A181-F194 HydrophobicContact CB-CB 3.59Å; A181-F194 HydrophobicContact CB-CD1 4.36Å; A181-F194 HydrophobicContact CB-CD2 4.1Å; A181-F194 HydrophobicContact CB-CG 3.78Å; C184-F194 HydrophobicContact CB-CD2 4.09Å; C184-F194 HydrophobicContact CB-CE2 3.95Å; Y185-F194 HydrophobicContact CE1-CB 4.32Å; Y185-F194 VanDerWaalsContact OH-CB 3.31Å; Y185-F194 WeakPolarHBondContact OH-CB 3.3Å; Y185-F194 PolarHBondContact OH-O 3.23Å; D192-F194 VanDerWaalsContact C-N 3.26Å; D192-F194 HydrophobicContact CB-CD2 3.77Å; D192-F194 HydrophobicContact CB-CE2 3.39Å; D192-F194 HydrophobicContact CB-CZ 4.11Å; D192-F194 PolarHBondContact O-N 3.32Å
195	T	94.1	Very high	95.1	Very high	32 Å²	32	51.3 Å²	51.3	20%	0.196	29%	0.292	C	S	.	.	B	Isolated β-bridge	trans	-123.4	148.2	-177.7	55.3	0	0	0	0	111.8	Y174 F193 Y199	Y174-T195 HydrophobicContact CD2-CG2 4.08Å; Y174-T195 CarbonylContact O-C 3.43Å; Y174-T195 WeakPolarHBondContact O-CA 3.34Å; F193-T195 HydrophobicContact CD1-CG2 3.77Å; F193-T195 HydrophobicContact CD2-CG2 4.19Å; F193-T195 HydrophobicContact CE1-CG2 3.45Å; F193-T195 VanDerWaalsContact CE1-CG2 3.45Å; F193-T195 HydrophobicContact CE2-CG2 3.89Å; F193-T195 HydrophobicContact CG-CG2 4.16Å; F193-T195 HydrophobicContact CZ-CG2 3.54Å; F193-T195 PolarHBondContact O-N 2.98Å; T195-Y199 HydrophobicContact CG2-CD1 3.59Å; T195-Y199 HydrophobicContact CG2-CE1 3.72Å
196	N	94.2	Very high	95.1	Very high	43 Å²	43	53.4 Å²	53.4	23%	0.23	31%	0.308	C	S	.	.			trans	-73.4	153.7	165.7	65.9	71.1	0	0	0	110.5	W173 Y174 R175 A198 Y199 A200	W173-N196 PolarHBondContact O-ND2 3.35Å; Y174-N196 VanDerWaalsContact C-ND2 3.26Å; Y174-N196 PolarHBondContact O-N 3.26Å; Y174-N196 PolarHBondContact O-ND2 2.92Å; Y174-N196 VanDerWaalsContact O-ND2 3.1Å; R175-N196 PolarHBondContact O-ND2 3.01Å; R175-N196 VanDerWaalsContact O-ND2 3.12Å; N196-A198 VanDerWaalsContact C-N 3.26Å; N196-A198 PolarHBondContact O-N 3.46Å; N196-A198 PolarHBondContact OD1-N 3.42Å; N196-Y199 PolarHBondContact O-N 2.92Å; N196-Y199 WeakPolarHBondContact OD1-CB 3.26Å; N196-Y199 PolarHBondContact OD1-N 3.36Å; N196-A200 PolarHBondContact O-N 2.7Å
197	Q	93.3	Very high	94.9	Very high	128 Å²	128	49.8 Å²	49.8	60%	0.598	28%	0.278	S	S	*	.	H	α-helix	trans	-58.2	-38.6	-174.8	-59.1	-172.7	-34.1	0	0	112.7	A200 I201 V297	Q197-A200 PolarHBondContact O-N 3.3Å; Q197-I201 VanDerWaalsContact O-CG1 3.32Å; Q197-I201 WeakPolarHBondContact O-CG1 3.36Å; Q197-I201 PolarHBondContact O-N 2.85Å; Q197-V297 HydrophobicContact CB-CG1 3.62Å; Q197-V297 HydrophobicContact CG-CG1 3.81Å; Q197-V297 PolarHBondContact NE2-O 2.86Å
198	A	94.8	Very high	95	Very high	71 Å²	71	46.3 Å²	46.3	59%	0.587	26%	0.259	S	S	*	.	H	α-helix	trans	-64.2	-47.9	-178.4	0	0	0	0	0	111.5	N196 A202	N196-A198 VanDerWaalsContact C-N 3.26Å; N196-A198 PolarHBondContact O-N 3.46Å; N196-A198 PolarHBondContact OD1-N 3.42Å; A198-A202 WeakPolarHBondContact O-CB 3.47Å; A198-A202 PolarHBondContact O-N 3.46Å
199	Y	95.3	Very high	95	Very high	20 Å²	20	42.6 Å²	42.6	8%	0.078	24%	0.24	C	C	.	.	H	α-helix	trans	-62.9	-48.3	175.9	172.4	-94.6	0	0	0	111.5	P168 F193 T195 N196 I201 A202 S203	P168-Y199 HydrophobicContact CB-CD2 3.88Å; P168-Y199 HydrophobicContact CB-CE2 3.45Å; P168-Y199 VanDerWaalsContact CB-CE2 3.45Å; P168-Y199 HydrophobicContact CG-CE2 4.13Å; F193-Y199 HydrophobicContact CE1-CE1 4.13Å; F193-Y199 AromaticContact CZ-CE1 3.58Å; F193-Y199 HydrophobicContact CZ-CE1 3.58Å; T195-Y199 HydrophobicContact CG2-CD1 3.59Å; T195-Y199 HydrophobicContact CG2-CE1 3.72Å; N196-Y199 PolarHBondContact O-N 2.92Å; N196-Y199 WeakPolarHBondContact OD1-CB 3.26Å; N196-Y199 PolarHBondContact OD1-N 3.36Å; Y199-I201 VanDerWaalsContact C-N 3.32Å; Y199-I201 PolarHBondContact O-N 2.97Å; Y199-A202 PolarHBondContact O-N 3.24Å; Y199-S203 WeakPolarHBondContact O-CB 3.26Å; Y199-S203 PolarHBondContact O-N 2.97Å
200	A	94.2	Very high	95	Very high	2 Å²	2	43.5 Å²	43.5	2%	0.017	25%	0.246	C	C	.	.	H	α-helix	trans	-58.9	-42.4	-176.9	0	0	0	0	0	112.4	N196 Q197 S204 V297	N196-A200 PolarHBondContact O-N 2.7Å; Q197-A200 PolarHBondContact O-N 3.3Å; A200-S204 WeakPolarHBondContact O-CB 3.38Å; A200-S204 PolarHBondContact O-N 3.43Å; A200-S204 PolarHBondContact O-OG 3.44Å; A200-V297 HydrophobicContact CB-CG2 3.3Å
201	I	95.2	Very high	95.1	Very high	71 Å²	71	42.8 Å²	42.8	36%	0.364	24%	0.24	S	C	.	.	H	α-helix	trans	-70.7	-53.2	176.2	-64.9	168.7	0	0	0	110.7	Q197 Y199 S203 S204 I205 I294 V297	Q197-I201 VanDerWaalsContact O-CG1 3.32Å; Q197-I201 WeakPolarHBondContact O-CG1 3.36Å; Q197-I201 PolarHBondContact O-N 2.85Å; Y199-I201 VanDerWaalsContact C-N 3.32Å; Y199-I201 PolarHBondContact O-N 2.97Å; I201-S203 PolarHBondContact O-N 2.84Å; I201-S204 PolarHBondContact O-N 2.98Å; I201-I205 HydrophobicContact CG2-CD1 3.65Å; I201-I205 HydrophobicContact CG2-CG1 4.43Å; I201-I205 VanDerWaalsContact O-CG1 3.3Å; I201-I205 WeakPolarHBondContact O-CG1 3.26Å; I201-I205 PolarHBondContact O-N 3.3Å; I201-I294 HydrophobicContact CG1-CD1 4.39Å; I201-V297 HydrophobicContact CD1-CG1 3.74Å; I201-V297 HydrophobicContact CG1-CG1 3.81Å
202	A	95.7	Very high	95.1	Very high	54 Å²	54	43.2 Å²	43.2	45%	0.446	24%	0.242	S	C	.	.	H	α-helix	trans	-63.1	-46.5	-173.9	0	0	0	0	0	111.9	A198 Y199 I205 V206	A198-A202 WeakPolarHBondContact O-CB 3.47Å; A198-A202 PolarHBondContact O-N 3.46Å; Y199-A202 PolarHBondContact O-N 3.24Å; A202-I205 PolarHBondContact O-N 2.93Å; A202-V206 WeakPolarHBondContact O-CG2 3.23Å; A202-V206 PolarHBondContact O-N 3.1Å
203	S	94.9	Very high	95.3	Very high	21 Å²	21	45.8 Å²	45.8	15%	0.147	26%	0.259	C	S	.	.	H	α-helix	trans	-63.2	-45.1	177.4	179.9	0	0	0	0	111.1	Y199 I201 I205 V206 S207	Y199-S203 WeakPolarHBondContact O-CB 3.26Å; Y199-S203 PolarHBondContact O-N 2.97Å; I201-S203 PolarHBondContact O-N 2.84Å; S203-I205 VanDerWaalsContact C-N 3.33Å; S203-I205 PolarHBondContact O-N 2.88Å; S203-V206 PolarHBondContact O-N 3Å; S203-S207 WeakPolarHBondContact O-CB 3.39Å; S203-S207 PolarHBondContact O-N 2.87Å; S203-S207 PolarHBondContact O-OG 2.86Å
204	S	95.7	Very high	95.5	Very high	3 Å²	3	46.2 Å²	46.2	2%	0.021	26%	0.264	C	S	.	.	H	α-helix	trans	-60.9	-40.7	177.1	-62	0	0	0	0	112.6	A200 I201 F208 Y209 N293	A200-S204 WeakPolarHBondContact O-CB 3.38Å; A200-S204 PolarHBondContact O-N 3.43Å; A200-S204 PolarHBondContact O-OG 3.44Å; I201-S204 PolarHBondContact O-N 2.98Å; S204-F208 WeakPolarHBondContact O-CB 3.18Å; S204-F208 PolarHBondContact O-N 3.29Å; S204-F208 VanDerWaalsContact O-N 3.09Å; S204-Y209 VanDerWaalsContact O-CD2 3.31Å; S204-Y209 WeakPolarHBondContact O-CD2 3.29Å; S204-Y209 PolarHBondContact O-N 3.43Å; S204-Y209 VanDerWaalsContact O-N 3.07Å; S204-N293 PolarHBondContact OG-ND2 3.16Å
205	I	96	Very high	95.7	Very high	76 Å²	76	44.3 Å²	44.3	39%	0.39	26%	0.256	S	S	.	.	I	π-helix	trans	-65.5	-51.6	179.5	-70.5	171.9	0	0	0	110.8	I201 A202 S203 Y209 V210	I201-I205 HydrophobicContact CG2-CD1 3.65Å; I201-I205 HydrophobicContact CG2-CG1 4.43Å; I201-I205 VanDerWaalsContact O-CG1 3.3Å; I201-I205 WeakPolarHBondContact O-CG1 3.26Å; I201-I205 PolarHBondContact O-N 3.3Å; A202-I205 PolarHBondContact O-N 2.93Å; S203-I205 VanDerWaalsContact C-N 3.33Å; S203-I205 PolarHBondContact O-N 2.88Å; I205-Y209 HydrophobicContact CG1-CD2 4.37Å; I205-Y209 PolarHBondContact O-N 2.94Å; I205-V210 HydrophobicContact CG2-CG2 3.85Å; I205-V210 WeakPolarHBondContact O-CB 3.43Å; I205-V210 WeakPolarHBondContact O-CG2 3.4Å; I205-V210 PolarHBondContact O-N 3.32Å
206	V	94.8	Very high	95.8	Very high	78 Å²	78	46.1 Å²	46.1	47%	0.473	27%	0.267	S	S	.	.	I	π-helix	trans	-69.5	-48.2	-175.5	174.1	0	0	0	0	111.1	T164 A202 S203 P211	T164-V206 HydrophobicContact CG2-CG1 4.15Å; A202-V206 WeakPolarHBondContact O-CG2 3.23Å; A202-V206 PolarHBondContact O-N 3.1Å; S203-V206 PolarHBondContact O-N 3Å; V206-P211 WeakPolarHBondContact O-CD 3.14Å
207	S	93.5	Very high	96	Very high	5 Å²	5	50.6 Å²	50.6	4%	0.035	28%	0.284	C	S	.	.	I	π-helix	trans	-79.8	-22.3	-173.1	-66.4	0	0	0	0	114	T118 I121 S203	T118-S207 WeakPolarHBondContact OG1-CB 3.14Å; T118-S207 PolarHBondContact OG1-OG 3.05Å; I121-S207 WeakPolarHBondContact CG2-O 3.4Å; S203-S207 WeakPolarHBondContact O-CB 3.39Å; S203-S207 PolarHBondContact O-N 2.87Å; S203-S207 PolarHBondContact O-OG 2.86Å
208	F	96.5	Very high	96.1	Very high	0 Å²	0	45.4 Å²	45.4	0%	0	26%	0.261	C	S	.	.	I	π-helix	trans	-130.6	-59.1	-174.9	-178.3	-100.3	0	0	0	114	I121 S204 V210 P211 L212 F282 W286 L287 F290	I121-F208 HydrophobicContact CD1-CD2 3.56Å; I121-F208 HydrophobicContact CD1-CE2 3.86Å; I121-F208 HydrophobicContact CD1-CG 4.26Å; I121-F208 WeakPolarHBondContact CD1-O 3.31Å; S204-F208 WeakPolarHBondContact O-CB 3.18Å; S204-F208 PolarHBondContact O-N 3.29Å; S204-F208 VanDerWaalsContact O-N 3.09Å; F208-V210 PolarHBondContact O-N 3.39Å; F208-P211 WeakPolarHBondContact O-CD 3.46Å; F208-L212 HydrophobicContact CD1-CD2 4.41Å; F208-L212 HydrophobicContact CE1-CD2 3.66Å; F208-L212 HydrophobicContact CZ-CD2 3.87Å; F208-L212 WeakPolarHBondContact O-CB 3.19Å; F208-L212 PolarHBondContact O-N 3.4Å; F208-F282 HydrophobicContact CD2-CE1 4.34Å; F208-F282 AromaticContact CE2-CE1 3.91Å; F208-F282 HydrophobicContact CE2-CE1 3.91Å; F208-W286 HydrophobicContact CD2-CB 4.48Å; F208-W286 HydrophobicContact CE2-CB 3.58Å; F208-W286 HydrophobicContact CZ-CB 4.06Å; F208-L287 HydrophobicContact CE1-CD1 3.91Å; F208-L287 HydrophobicContact CZ-CB 4.2Å; F208-L287 HydrophobicContact CZ-CD1 4.32Å; F208-F290 HydrophobicContact CB-CD1 3.76Å; F208-F290 HydrophobicContact CB-CD2 4.04Å; F208-F290 HydrophobicContact CB-CE1 3.54Å; F208-F290 HydrophobicContact CB-CE2 3.84Å; F208-F290 HydrophobicContact CB-CG 4.01Å; F208-F290 HydrophobicContact CB-CZ 3.59Å; F208-F290 HydrophobicContact CD1-CB 3.62Å; F208-F290 AromaticContact CD1-CD1 3.94Å; F208-F290 HydrophobicContact CD1-CD1 3.94Å; F208-F290 AromaticContact CD1-CD2 3.54Å; F208-F290 HydrophobicContact CD1-CD2 3.54Å; F208-F290 HydrophobicContact CD1-CE2 4.18Å; F208-F290 AromaticContact CD1-CG 3.41Å; F208-F290 HydrophobicContact CD1-CG 3.41Å; F208-F290 VanDerWaalsContact CD1-CG 3.41Å; F208-F290 AromaticContact CD2-CD2 3.39Å; F208-F290 HydrophobicContact CD2-CD2 3.39Å; F208-F290 AromaticContact CD2-CE2 3.3Å; F208-F290 HydrophobicContact CD2-CE2 3.3Å; F208-F290 HydrophobicContact CD2-CG 4.1Å; F208-F290 AromaticContact CD2-CZ 3.94Å; F208-F290 HydrophobicContact CD2-CZ 3.94Å; F208-F290 HydrophobicContact CE1-CB 3.66Å; F208-F290 AromaticContact CE1-CD2 3.71Å; F208-F290 HydrophobicContact CE1-CD2 3.71Å; F208-F290 AromaticContact CE1-CG 3.8Å; F208-F290 HydrophobicContact CE1-CG 3.8Å; F208-F290 AromaticContact CE2-CD2 3.57Å; F208-F290 HydrophobicContact CE2-CD2 3.57Å; F208-F290 AromaticContact CE2-CE2 3.81Å; F208-F290 HydrophobicContact CE2-CE2 3.81Å; F208-F290 HydrophobicContact CE2-CG 4.43Å; F208-F290 HydrophobicContact CG-CB 4.3Å; F208-F290 AromaticContact CG-CD1 3.88Å; F208-F290 HydrophobicContact CG-CD1 3.88Å; F208-F290 AromaticContact CG-CD2 3.36Å; F208-F290 HydrophobicContact CG-CD2 3.36Å; F208-F290 HydrophobicContact CG-CE1 4Å; F208-F290 AromaticContact CG-CE2 3.51Å; F208-F290 HydrophobicContact CG-CE2 3.51Å; F208-F290 AromaticContact CG-CG 3.57Å; F208-F290 HydrophobicContact CG-CG 3.57Å; F208-F290 AromaticContact CG-CZ 3.83Å; F208-F290 HydrophobicContact CG-CZ 3.83Å; F208-F290 HydrophobicContact CZ-CB 4.38Å; F208-F290 AromaticContact CZ-CD2 3.73Å; F208-F290 HydrophobicContact CZ-CD2 3.73Å; F208-F290 HydrophobicContact CZ-CE2 4.43Å; F208-F290 HydrophobicContact CZ-CG 4.3Å
209	Y	97.5	Very high	96.1	Very high	53 Å²	53	43.1 Å²	43.1	21%	0.208	24%	0.238	C	C	.	.	I	π-helix	trans	-67.6	-40.6	-170	-68.5	-71.5	0	0	0	113.6	S204 I205 L212 V213 L287 F290 I291 I294	S204-Y209 VanDerWaalsContact O-CD2 3.31Å; S204-Y209 WeakPolarHBondContact O-CD2 3.29Å; S204-Y209 PolarHBondContact O-N 3.43Å; S204-Y209 VanDerWaalsContact O-N 3.07Å; I205-Y209 HydrophobicContact CG1-CD2 4.37Å; I205-Y209 PolarHBondContact O-N 2.94Å; Y209-L212 PolarHBondContact O-N 3.4Å; Y209-V213 VanDerWaalsContact O-CG2 3.29Å; Y209-V213 WeakPolarHBondContact O-CG2 3.45Å; Y209-V213 PolarHBondContact O-N 3.15Å; Y209-L287 HydrophobicContact CE1-CD1 4.34Å; Y209-F290 HydrophobicContact CE2-CB 4.38Å; Y209-F290 PolarHBondContact OH-O 3.01Å; Y209-I291 PolarHBondContact OH-N 2.66Å; Y209-I294 HydrophobicContact CE2-CD1 4.2Å; Y209-I294 HydrophobicContact CE2-CG1 3.73Å
210	V	97	Very high	96.1	Very high	75 Å²	75	44.9 Å²	44.9	46%	0.455	25%	0.253	S	S	.	.	H	α-helix	trans	-63.4	-54	177.2	167.3	0	0	0	0	111	I205 F208 L212 V213 I214	I205-V210 HydrophobicContact CG2-CG2 3.85Å; I205-V210 WeakPolarHBondContact O-CB 3.43Å; I205-V210 WeakPolarHBondContact O-CG2 3.4Å; I205-V210 PolarHBondContact O-N 3.32Å; F208-V210 PolarHBondContact O-N 3.39Å; V210-L212 VanDerWaalsContact C-N 3.3Å; V210-L212 PolarHBondContact O-N 2.88Å; V210-V213 PolarHBondContact O-N 2.92Å; V210-I214 HydrophobicContact CG1-CD1 3.93Å; V210-I214 WeakPolarHBondContact O-CG1 3.31Å; V210-I214 PolarHBondContact O-N 2.94Å; V210-I214 VanDerWaalsContact O-N 3.15Å
211	P	97.1	Very high	96.1	Very high	10 Å²	10	50.1 Å²	50.1	7%	0.065	27%	0.272	C	S	.	.	H	α-helix	trans	-56.2	-40.2	172.7	-28.5	35.6	0	0	0	113.8	I121 E122 C125 V206 F208 I214 M215	I121-P211 HydrophobicContact CD1-CB 4.04Å; I121-P211 HydrophobicContact CG1-CB 3.82Å; I121-P211 HydrophobicContact CG2-CB 4.13Å; I121-P211 HydrophobicContact CG2-CG 4.39Å; E122-P211 HydrophobicContact CG-CG 4.38Å; C125-P211 HydrophobicContact CB-CB 4.44Å; V206-P211 WeakPolarHBondContact O-CD 3.14Å; F208-P211 WeakPolarHBondContact O-CD 3.46Å; P211-I214 PolarHBondContact O-N 2.98Å; P211-M215 WeakPolarHBondContact O-CB 3.3Å; P211-M215 PolarHBondContact O-N 3.45Å
212	L	97.9	Very high	96.1	Very high	15 Å²	15	46.8 Å²	46.8	8%	0.079	26%	0.255	C	S	.	.	H	α-helix	trans	-62.2	-49.3	-179.6	178	63.3	0	0	0	111.6	I121 F208 Y209 V210 I214 M215 V216 T283 L287	I121-L212 HydrophobicContact CD1-CB 3.9Å; F208-L212 HydrophobicContact CD1-CD2 4.41Å; F208-L212 HydrophobicContact CE1-CD2 3.66Å; F208-L212 HydrophobicContact CZ-CD2 3.87Å; F208-L212 WeakPolarHBondContact O-CB 3.19Å; F208-L212 PolarHBondContact O-N 3.4Å; Y209-L212 PolarHBondContact O-N 3.4Å; V210-L212 VanDerWaalsContact C-N 3.3Å; V210-L212 PolarHBondContact O-N 2.88Å; L212-I214 VanDerWaalsContact C-N 3.35Å; L212-I214 PolarHBondContact O-N 3.35Å; L212-M215 HydrophobicContact CD1-CE 3.71Å; L212-M215 PolarHBondContact O-N 3.45Å; L212-V216 HydrophobicContact CD1-CG2 3.94Å; L212-V216 HydrophobicContact CG-CG2 4.44Å; L212-V216 WeakPolarHBondContact O-CB 3.38Å; L212-V216 VanDerWaalsContact O-CG2 3.29Å; L212-V216 WeakPolarHBondContact O-CG2 3.46Å; L212-V216 PolarHBondContact O-N 3.34Å; L212-T283 HydrophobicContact CD1-CG2 3.77Å; L212-T283 WeakPolarHBondContact CD1-OG1 3.42Å; L212-L287 HydrophobicContact CD2-CD1 4.07Å
213	V	97.9	Very high	95.9	Very high	97 Å²	97	49 Å²	49	59%	0.588	26%	0.255	S	S	*	.	H	α-helix	trans	-62.2	-44.5	-179.7	170.4	0	0	0	0	110.5	Y209 V210 F217	Y209-V213 VanDerWaalsContact O-CG2 3.29Å; Y209-V213 WeakPolarHBondContact O-CG2 3.45Å; Y209-V213 PolarHBondContact O-N 3.15Å; V210-V213 PolarHBondContact O-N 2.92Å; V213-F217 VanDerWaalsContact O-CB 3.24Å; V213-F217 WeakPolarHBondContact O-CB 3.11Å; V213-F217 PolarHBondContact O-N 3.23Å
214	I	97.3	Very high	95.8	Very high	75 Å²	75	52.1 Å²	52.1	39%	0.385	27%	0.267	S	S	.	.	H	α-helix	trans	-62.3	-50.3	177.2	-63.7	168.4	0	0	0	110.1	C125 V210 P211 L212 V216 F217 V218	C125-I214 WeakPolarHBondContact SG-CG2 3.39Å; V210-I214 HydrophobicContact CG1-CD1 3.93Å; V210-I214 WeakPolarHBondContact O-CG1 3.31Å; V210-I214 PolarHBondContact O-N 2.94Å; V210-I214 VanDerWaalsContact O-N 3.15Å; P211-I214 PolarHBondContact O-N 2.98Å; L212-I214 VanDerWaalsContact C-N 3.35Å; L212-I214 PolarHBondContact O-N 3.35Å; I214-V216 PolarHBondContact O-N 3.47Å; I214-F217 PolarHBondContact O-N 3.33Å; I214-V218 HydrophobicContact CG2-CG2 4.02Å; I214-V218 VanDerWaalsContact O-CB 3.31Å; I214-V218 WeakPolarHBondContact O-CB 3.34Å; I214-V218 WeakPolarHBondContact O-CG2 3.23Å; I214-V218 PolarHBondContact O-N 3.24Å
215	M	96.9	Very high	95.6	Very high	2 Å²	2	54 Å²	54	1%	0.01	28%	0.275	C	S	.	.	H	α-helix	trans	-56.3	-52.1	179.7	-179.2	-172.7	64.9	0	0	111.2	L124 C125 A128 P211 L212 F217 V218 Y219 M279	L124-M215 HydrophobicContact CB-SD 3.54Å; L124-M215 VanDerWaalsContact CB-SD 3.54Å; L124-M215 HydrophobicContact CD1-SD 4.31Å; C125-M215 HydrophobicContact CB-CB 4.34Å; A128-M215 HydrophobicContact CB-CG 4.15Å; P211-M215 WeakPolarHBondContact O-CB 3.3Å; P211-M215 PolarHBondContact O-N 3.45Å; L212-M215 HydrophobicContact CD1-CE 3.71Å; L212-M215 PolarHBondContact O-N 3.45Å; M215-F217 PolarHBondContact O-N 3.16Å; M215-V218 PolarHBondContact O-N 3.22Å; M215-Y219 WeakPolarHBondContact O-CB 3.41Å; M215-Y219 PolarHBondContact O-N 2.96Å; M215-M279 HydrophobicContact CE-CB 4.19Å; M215-M279 HydrophobicContact CG-CG 4.25Å; M215-M279 HydrophobicContact CG-SD 3.93Å; M215-M279 HydrophobicContact SD-CB 3.82Å; M215-M279 HydrophobicContact SD-CG 3.67Å; M215-M279 HydrophobicContact SD-SD 4.16Å
216	V	96.7	Very high	95.2	Very high	70 Å²	70	50.7 Å²	50.7	42%	0.424	26%	0.259	S	S	.	.	H	α-helix	trans	-62.2	-45.3	-178.9	171.1	0	0	0	0	111.2	L212 I214 S220	L212-V216 HydrophobicContact CD1-CG2 3.94Å; L212-V216 HydrophobicContact CG-CG2 4.44Å; L212-V216 WeakPolarHBondContact O-CB 3.38Å; L212-V216 VanDerWaalsContact O-CG2 3.29Å; L212-V216 WeakPolarHBondContact O-CG2 3.46Å; L212-V216 PolarHBondContact O-N 3.34Å; I214-V216 PolarHBondContact O-N 3.47Å; V216-S220 VanDerWaalsContact O-CB 3.26Å; V216-S220 WeakPolarHBondContact O-CB 3.39Å; V216-S220 PolarHBondContact O-N 3.28Å; V216-S220 PolarHBondContact O-OG 2.94Å
217	F	97.4	Very high	94.9	Very high	137 Å²	137	52.4 Å²	52.4	60%	0.601	26%	0.261	S	S	*	.	H	α-helix	trans	-62.1	-52.9	178.7	173.3	-101.3	0	0	0	111.7	V213 I214 M215 Y219 S220 R221	V213-F217 VanDerWaalsContact O-CB 3.24Å; V213-F217 WeakPolarHBondContact O-CB 3.11Å; V213-F217 PolarHBondContact O-N 3.23Å; I214-F217 PolarHBondContact O-N 3.33Å; M215-F217 PolarHBondContact O-N 3.16Å; F217-Y219 PolarHBondContact O-N 3.12Å; F217-S220 WeakPolarHBondContact O-CB 3.27Å; F217-S220 PolarHBondContact O-N 3.49Å; F217-R221 HydrophobicContact CZ-CG 4.4Å; F217-R221 WeakPolarHBondContact O-CG 3.34Å; F217-R221 PolarHBondContact O-N 3.34Å
218	V	96.7	Very high	94.7	Very high	19 Å²	19	58 Å²	58	12%	0.115	28%	0.281	C	S	.	.	H	α-helix	trans	-62.6	-45.5	-178	173.9	0	0	0	0	110.3	A128 V129 Y132 I214 M215 S220 R221 V222	A128-V218 HydrophobicContact CB-CB 4.31Å; A128-V218 HydrophobicContact CB-CG1 4.1Å; A128-V218 WeakPolarHBondContact O-CG1 3.43Å; V129-V218 HydrophobicContact CG2-CG1 4.26Å; V129-V218 HydrophobicContact CG2-CG2 4.33Å; Y132-V218 HydrophobicContact CG-CG1 4.17Å; I214-V218 HydrophobicContact CG2-CG2 4.02Å; I214-V218 VanDerWaalsContact O-CB 3.31Å; I214-V218 WeakPolarHBondContact O-CB 3.34Å; I214-V218 WeakPolarHBondContact O-CG2 3.23Å; I214-V218 PolarHBondContact O-N 3.24Å; M215-V218 PolarHBondContact O-N 3.22Å; V218-S220 VanDerWaalsContact C-N 3.32Å; V218-S220 PolarHBondContact O-N 3.16Å; V218-R221 WeakPolarHBondContact O-CA 3.37Å; V218-R221 WeakPolarHBondContact O-CB 3.38Å; V218-R221 PolarHBondContact O-N 3.28Å; V218-V222 WeakPolarHBondContact O-CG2 3.44Å; V218-V222 PolarHBondContact O-N 3.47Å
219	Y	93.6	Very high	94.1	Very high	23 Å²	23	60.7 Å²	60.7	9%	0.09	29%	0.294	C	S	.	.	H	α-helix	trans	-68.7	-32.2	-178.3	-150.4	-98.3	0	0	0	113.1	A128 M215 F217 R221 V222 F223 L272 L275 G276 M279	A128-Y219 HydrophobicContact CB-CD2 3.93Å; M215-Y219 WeakPolarHBondContact O-CB 3.41Å; M215-Y219 PolarHBondContact O-N 2.96Å; F217-Y219 PolarHBondContact O-N 3.12Å; Y219-R221 VanDerWaalsContact C-N 3.28Å; Y219-R221 PolarHBondContact O-N 3.02Å; Y219-V222 WeakPolarHBondContact O-CB 3.43Å; Y219-V222 PolarHBondContact O-N 3.13Å; Y219-F223 PolarHBondContact O-N 2.93Å; Y219-L272 PolarHBondContact OH-O 2.9Å; Y219-L275 HydrophobicContact CE2-CB 4.36Å; Y219-L275 VanDerWaalsContact OH-CB 3.27Å; Y219-L275 WeakPolarHBondContact OH-CB 3.48Å; Y219-G276 PolarHBondContact OH-N 3.18Å; Y219-G276 VanDerWaalsContact OH-N 3.17Å; Y219-M279 HydrophobicContact CD1-SD 4.02Å; Y219-M279 HydrophobicContact CD2-CE 3.53Å; Y219-M279 HydrophobicContact CD2-SD 3.22Å; Y219-M279 WeakPolarHBondContact CD2-SD 3.31Å; Y219-M279 HydrophobicContact CE1-SD 4.33Å; Y219-M279 HydrophobicContact CE2-CE 3.54Å; Y219-M279 HydrophobicContact CE2-SD 3.58Å; Y219-M279 VanDerWaalsContact CE2-SD 3.58Å; Y219-M279 HydrophobicContact CG-CE 4.37Å; Y219-M279 HydrophobicContact CG-SD 3.45Å
220	S	95.2	Very high	93.4	Very high	57 Å²	57	60.7 Å²	60.7	40%	0.399	30%	0.297	S	S	.	.	H	α-helix	trans	-60.5	-39.7	170.3	-63.3	0	0	0	0	111.4	V216 F217 V218 F223 Q224	V216-S220 VanDerWaalsContact O-CB 3.26Å; V216-S220 WeakPolarHBondContact O-CB 3.39Å; V216-S220 PolarHBondContact O-N 3.28Å; V216-S220 PolarHBondContact O-OG 2.94Å; F217-S220 WeakPolarHBondContact O-CB 3.27Å; F217-S220 PolarHBondContact O-N 3.49Å; V218-S220 VanDerWaalsContact C-N 3.32Å; V218-S220 PolarHBondContact O-N 3.16Å; S220-F223 PolarHBondContact O-N 3.33Å; S220-Q224 VanDerWaalsContact O-CG 3.28Å; S220-Q224 WeakPolarHBondContact O-CG 3.39Å; S220-Q224 PolarHBondContact O-N 3.18Å
221	R	95.7	Very high	92.8	Very high	111 Å²	111	61.8 Å²	61.8	42%	0.419	30%	0.297	S	S	.	.	H	α-helix	trans	-67.9	-39.5	174.8	-61	-71.2	-82.6	-170.9	-12.5	111.9	Y132 F217 V218 Y219 F223 Q224 E225	Y132-R221 HydrophobicContact CD2-CB 4.12Å; Y132-R221 HydrophobicContact CE2-CB 3.94Å; F217-R221 HydrophobicContact CZ-CG 4.4Å; F217-R221 WeakPolarHBondContact O-CG 3.34Å; F217-R221 PolarHBondContact O-N 3.34Å; V218-R221 WeakPolarHBondContact O-CA 3.37Å; V218-R221 WeakPolarHBondContact O-CB 3.38Å; V218-R221 PolarHBondContact O-N 3.28Å; Y219-R221 VanDerWaalsContact C-N 3.28Å; Y219-R221 PolarHBondContact O-N 3.02Å; R221-F223 VanDerWaalsContact C-N 3.34Å; R221-F223 PolarHBondContact O-N 2.68Å; R221-Q224 PolarHBondContact O-N 2.81Å; R221-E225 PolarHBondContact O-N 3.42Å
222	V	93.6	Very high	92.1	Very high	1 Å²	1	68.2 Å²	68.2	1%	0.006	32%	0.324	C	S	.	.	H	α-helix	trans	-56.5	-49.1	172.6	174.7	0	0	0	0	110.6	R131 Y132 I135 V218 Y219 Q224 E225 A226 L272	R131-V222 HydrophobicContact CB-CG1 4.23Å; R131-V222 HydrophobicContact CB-CG2 4.24Å; Y132-V222 HydrophobicContact CD2-CG2 4.26Å; I135-V222 HydrophobicContact CG2-CG1 4.46Å; V218-V222 WeakPolarHBondContact O-CG2 3.44Å; V218-V222 PolarHBondContact O-N 3.47Å; Y219-V222 WeakPolarHBondContact O-CB 3.43Å; Y219-V222 PolarHBondContact O-N 3.13Å; V222-Q224 PolarHBondContact O-N 3.38Å; V222-E225 PolarHBondContact O-N 3.5Å; V222-A226 WeakPolarHBondContact O-CB 3.41Å; V222-A226 PolarHBondContact O-N 3.34Å; V222-L272 HydrophobicContact CG1-CD1 4.17Å; V222-L272 HydrophobicContact CG1-CD2 3.7Å
223	F	91.3	Very high	91.3	Very high	102 Å²	102	69.3 Å²	69.3	45%	0.447	33%	0.329	S	S	.	.	H	α-helix	trans	-65.2	-39.7	-179.4	-167.8	-97.1	0	0	0	112.3	Y219 S220 R221 K227	Y219-F223 PolarHBondContact O-N 2.93Å; S220-F223 PolarHBondContact O-N 3.33Å; R221-F223 VanDerWaalsContact C-N 3.34Å; R221-F223 PolarHBondContact O-N 2.68Å; F223-K227 WeakPolarHBondContact O-CB 3.47Å; F223-K227 PolarHBondContact O-N 3.23Å
224	Q	93.5	Very high	90.3	Very high	86 Å²	86	69.9 Å²	69.9	40%	0.402	33%	0.329	S	S	.	.	H	α-helix	trans	-61.5	-46.7	174.6	-73.8	174	20.6	0	0	111.9	S220 R221 V222 K227 R228	S220-Q224 VanDerWaalsContact O-CG 3.28Å; S220-Q224 WeakPolarHBondContact O-CG 3.39Å; S220-Q224 PolarHBondContact O-N 3.18Å; R221-Q224 PolarHBondContact O-N 2.81Å; V222-Q224 PolarHBondContact O-N 3.38Å; Q224-K227 PolarHBondContact O-N 3.49Å; Q224-R228 WeakPolarHBondContact O-CG 3.43Å; Q224-R228 PolarHBondContact O-N 3.42Å
225	E	90.9	Very high	89.4	Confident	42 Å²	42	73.2 Å²	73.2	20%	0.196	34%	0.341	C	S	.	.	H	α-helix	trans	-68.5	-38.3	-179	-164.6	56.5	-150.1	0	0	111.7	I135 T136 R221 V222 K227 R228 Q229	I135-E225 HydrophobicContact CD1-CB 4.28Å; I135-E225 HydrophobicContact CG1-CG 4.34Å; I135-E225 HydrophobicContact CG2-CB 4.37Å; I135-E225 HydrophobicContact CG2-CG 4.48Å; T136-E225 HydrophobicContact CG2-CG 4.49Å; R221-E225 PolarHBondContact O-N 3.42Å; V222-E225 PolarHBondContact O-N 3.5Å; E225-K227 VanDerWaalsContact C-N 3.34Å; E225-K227 PolarHBondContact O-N 3.14Å; E225-R228 WeakPolarHBondContact O-CB 3.46Å; E225-R228 PolarHBondContact O-N 3.23Å; E225-R228 WeakPolarHBondContact OE2-CD 3.47Å; E225-R228 IonicContact OE2-NH1 2.86Å; E225-R228 PolarHBondContact OE2-NH1 3.31Å; E225-R228 VanDerWaalsContact OE2-NH1 3.13Å; E225-Q229 WeakPolarHBondContact O-CG 3.38Å; E225-Q229 PolarHBondContact O-N 3.44Å
226	A	88.5	Confident	88.4	Confident	6 Å²	6	75 Å²	75	5%	0.05	35%	0.354	C	S	.	.	H	α-helix	trans	-60.6	-43.3	173.1	0	0	0	0	0	112.1	I135 V222 R228 Q229 L230 L272	I135-A226 VanDerWaalsContact CD1-CA 3.47Å; I135-A226 HydrophobicContact CD1-CB 3.51Å; I135-A226 VanDerWaalsContact CD1-N 3.33Å; V222-A226 WeakPolarHBondContact O-CB 3.41Å; V222-A226 PolarHBondContact O-N 3.34Å; A226-R228 VanDerWaalsContact C-N 3.34Å; A226-R228 PolarHBondContact O-N 3.41Å; A226-Q229 PolarHBondContact O-N 3.45Å; A226-L230 WeakPolarHBondContact O-CB 3.36Å; A226-L230 PolarHBondContact O-N 2.68Å; A226-L272 HydrophobicContact CB-CD1 3.67Å
227	K	88.5	Confident	87.1	Confident	115 Å²	115	74.2 Å²	74.2	50%	0.5	35%	0.345	S	S	.	.	H	α-helix	trans	-63.6	-40.5	176.3	-172.2	177.9	-179.8	-179.8	0	111.3	F223 Q224 E225 L230 Q231	F223-K227 WeakPolarHBondContact O-CB 3.47Å; F223-K227 PolarHBondContact O-N 3.23Å; Q224-K227 PolarHBondContact O-N 3.49Å; E225-K227 VanDerWaalsContact C-N 3.34Å; E225-K227 PolarHBondContact O-N 3.14Å; K227-L230 PolarHBondContact O-N 3.09Å; K227-Q231 WeakPolarHBondContact O-CB 3.23Å; K227-Q231 VanDerWaalsContact O-CG 3.3Å; K227-Q231 WeakPolarHBondContact O-CG 3.41Å; K227-Q231 PolarHBondContact O-N 2.94Å
228	R	88.4	Confident	85.5	Confident	121 Å²	121	69.4 Å²	69.4	46%	0.457	33%	0.334	S	S	.	.	H	α-helix	trans	-63.8	-43.1	176.2	-73	170.2	179	173.6	-2.1	112.2	Q224 E225 A226 Q231 K232	Q224-R228 WeakPolarHBondContact O-CG 3.43Å; Q224-R228 PolarHBondContact O-N 3.42Å; E225-R228 WeakPolarHBondContact O-CB 3.46Å; E225-R228 PolarHBondContact O-N 3.23Å; E225-R228 WeakPolarHBondContact OE2-CD 3.47Å; E225-R228 IonicContact OE2-NH1 2.86Å; E225-R228 PolarHBondContact OE2-NH1 3.31Å; E225-R228 VanDerWaalsContact OE2-NH1 3.13Å; A226-R228 VanDerWaalsContact C-N 3.34Å; A226-R228 PolarHBondContact O-N 3.41Å; R228-Q231 PolarHBondContact O-N 3.08Å; R228-K232 WeakPolarHBondContact O-CG 3.31Å; R228-K232 PolarHBondContact O-N 3.04Å
229	Q	84	Confident	83.8	Confident	58 Å²	58	76.4 Å²	76.4	27%	0.271	36%	0.359	S	S	.	.	H	α-helix	trans	-62.9	-44.5	176.4	-71.7	-179	5.7	0	0	111.4	I135 E225 A226 Q231 K232 I233	I135-Q229 PolarHBondContact O-NE2 3.21Å; E225-Q229 WeakPolarHBondContact O-CG 3.38Å; E225-Q229 PolarHBondContact O-N 3.44Å; A226-Q229 PolarHBondContact O-N 3.45Å; Q229-Q231 PolarHBondContact O-N 3.28Å; Q229-K232 PolarHBondContact O-N 3.44Å; Q229-I233 WeakPolarHBondContact O-CG1 3.48Å; Q229-I233 PolarHBondContact O-N 3.39Å
230	L	82.5	Confident	82.1	Confident	53 Å²	53	79.9 Å²	79.9	28%	0.277	38%	0.375	S	S	.	.	H	α-helix	trans	-62	-42.1	177.1	-170.9	65.2	0	0	0	112	A226 K227 K232 I233 D234	A226-L230 WeakPolarHBondContact O-CB 3.36Å; A226-L230 PolarHBondContact O-N 2.68Å; K227-L230 PolarHBondContact O-N 3.09Å; L230-K232 VanDerWaalsContact C-N 3.32Å; L230-K232 PolarHBondContact O-N 3.47Å; L230-I233 PolarHBondContact O-N 3.25Å; L230-D234 WeakPolarHBondContact O-CB 3.33Å; L230-D234 PolarHBondContact O-N 2.96Å
231	Q	84.9	Confident	80.4	Confident	97 Å²	97	83.6 Å²	83.6	45%	0.453	39%	0.385	S	S	.	.	H	α-helix	trans	-63.7	-35.3	175.8	-75.1	176.6	-14.5	0	0	112.9	K227 R228 Q229 K235	K227-Q231 WeakPolarHBondContact O-CB 3.23Å; K227-Q231 VanDerWaalsContact O-CG 3.3Å; K227-Q231 WeakPolarHBondContact O-CG 3.41Å; K227-Q231 PolarHBondContact O-N 2.94Å; R228-Q231 PolarHBondContact O-N 3.08Å; Q229-Q231 PolarHBondContact O-N 3.28Å; Q231-K235 WeakPolarHBondContact O-CB 3.47Å; Q231-K235 VanDerWaalsContact O-CG 3.23Å; Q231-K235 WeakPolarHBondContact O-CG 3.25Å; Q231-K235 PolarHBondContact O-N 3.07Å; Q231-K235 VanDerWaalsContact O-N 3.08Å
232	K	83.9	Confident	78.5	Confident	145 Å²	145	83.4 Å²	83.4	63%	0.63	40%	0.396	S	S	*	.	H	α-helix	trans	-68.2	-40.4	174.9	-72.8	175.7	-179.1	178.3	0	111.3	R228 Q229 L230 S236	R228-K232 WeakPolarHBondContact O-CG 3.31Å; R228-K232 PolarHBondContact O-N 3.04Å; Q229-K232 PolarHBondContact O-N 3.44Å; L230-K232 VanDerWaalsContact C-N 3.32Å; L230-K232 PolarHBondContact O-N 3.47Å; K232-S236 PolarHBondContact O-N 2.95Å; K232-S236 VanDerWaalsContact O-N 3.08Å; K232-S236 PolarHBondContact O-OG 2.99Å
233	I	79.3	Confident	76.6	Confident	38 Å²	38	88.7 Å²	88.7	20%	0.195	42%	0.421	C	S	.	.	H	α-helix	trans	-65.9	-48.6	177.3	-66.5	164.3	0	0	0	110.2	Q229 L230 K235 S236 E237 C265	Q229-I233 WeakPolarHBondContact O-CG1 3.48Å; Q229-I233 PolarHBondContact O-N 3.39Å; L230-I233 PolarHBondContact O-N 3.25Å; I233-K235 VanDerWaalsContact C-N 3.33Å; I233-K235 PolarHBondContact O-N 2.94Å; I233-S236 WeakPolarHBondContact CA-OG 3.43Å; I233-S236 CarbonylContact O-C 3.57Å; I233-S236 WeakPolarHBondContact O-CA 3.5Å; I233-S236 PolarHBondContact O-N 2.91Å; I233-S236 PolarHBondContact O-OG 3.37Å; I233-E237 HydrophobicContact CG2-CG 4.33Å; I233-E237 PolarHBondContact O-N 3.2Å; I233-C265 HydrophobicContact CD1-CB 3.72Å; I233-C265 WeakPolarHBondContact CD1-SG 3.46Å
234	D	77.7	Confident	74.7	Confident	109 Å²	109	87.4 Å²	87.4	58%	0.583	42%	0.419	S	S	*	.	H	α-helix	trans	-60.2	-41.3	178.5	-171	34.5	0	0	0	112.1	L230 S236 E237 G238	L230-D234 WeakPolarHBondContact O-CB 3.33Å; L230-D234 PolarHBondContact O-N 2.96Å; D234-S236 VanDerWaalsContact C-N 3.28Å; D234-S236 PolarHBondContact O-N 3.25Å; D234-E237 PolarHBondContact O-N 3.42Å; D234-G238 PolarHBondContact O-N 3.41Å
235	K	78.8	Confident	72.9	Confident	145 Å²	145	89.9 Å²	89.9	63%	0.63	43%	0.434	S	S	*	.	H	α-helix	trans	-64.8	-27.5	172.4	-74.8	179.4	-176.4	-172.8	0	114	Q231 I233 R239	Q231-K235 WeakPolarHBondContact O-CB 3.47Å; Q231-K235 VanDerWaalsContact O-CG 3.23Å; Q231-K235 WeakPolarHBondContact O-CG 3.25Å; Q231-K235 PolarHBondContact O-N 3.07Å; Q231-K235 VanDerWaalsContact O-N 3.08Å; I233-K235 VanDerWaalsContact C-N 3.33Å; I233-K235 PolarHBondContact O-N 2.94Å; K235-R239 WeakPolarHBondContact O-CG 3.49Å; K235-R239 PolarHBondContact O-NE 3.02Å
236	S	75.6	Confident	71.1	Confident	40 Å²	40	92.5 Å²	92.5	28%	0.28	46%	0.457	S	S	.	.	H	α-helix	trans	-78.1	-44.7	172.2	60.1	0	0	0	0	111.3	K232 I233 D234 G238 R239 F240	K232-S236 PolarHBondContact O-N 2.95Å; K232-S236 VanDerWaalsContact O-N 3.08Å; K232-S236 PolarHBondContact O-OG 2.99Å; I233-S236 WeakPolarHBondContact CA-OG 3.43Å; I233-S236 CarbonylContact O-C 3.57Å; I233-S236 WeakPolarHBondContact O-CA 3.5Å; I233-S236 PolarHBondContact O-N 2.91Å; I233-S236 PolarHBondContact O-OG 3.37Å; D234-S236 VanDerWaalsContact C-N 3.28Å; D234-S236 PolarHBondContact O-N 3.25Å; S236-G238 PolarHBondContact O-N 3.49Å; S236-R239 PolarHBondContact O-N 2.85Å; S236-F240 WeakPolarHBondContact O-CD2 3.3Å; S236-F240 PolarHBondContact O-N 3.43Å; S236-F240 VanDerWaalsContact O-N 3.11Å
237	E	70.1	Confident	69.3	Low	54 Å²	54	99.1 Å²	99.1	25%	0.252	49%	0.487	S	S	.	.	H	α-helix	trans	-63.3	-41.4	178.3	-68.5	-163.2	131.6	0	0	111.7	I233 D234 R239 F240 H241 S262	I233-E237 HydrophobicContact CG2-CG 4.33Å; I233-E237 PolarHBondContact O-N 3.2Å; D234-E237 PolarHBondContact O-N 3.42Å; E237-R239 VanDerWaalsContact C-N 3.3Å; E237-R239 PolarHBondContact O-N 3.37Å; E237-F240 PolarHBondContact O-N 2.91Å; E237-H241 WeakPolarHBondContact O-CB 3.35Å; E237-H241 PolarHBondContact O-N 2.95Å; E237-S262 VanDerWaalsContact CD-CB 3.47Å; E237-S262 WeakPolarHBondContact OE1-CB 3.39Å; E237-S262 VanDerWaalsContact OE2-CB 3.32Å; E237-S262 WeakPolarHBondContact OE2-CB 3.48Å; E237-S262 PolarHBondContact OE2-OG 2.95Å
238	G	62.8	Low	67.6	Low	36 Å²	36	98.7 Å²	98.7	37%	0.371	49%	0.494	S	S	.	.	H	α-helix	trans	-61.4	-35.2	174.8	0	0	0	0	0	113.3	D234 S236 V242	D234-G238 PolarHBondContact O-N 3.41Å; S236-G238 PolarHBondContact O-N 3.49Å; G238-V242 VanDerWaalsContact O-CG2 3.27Å; G238-V242 WeakPolarHBondContact O-CG2 3.5Å; G238-V242 PolarHBondContact O-N 3.28Å; G238-V242 VanDerWaalsContact O-N 3.16Å
239	R	61.2	Low	65.6	Low	166 Å²	166	102.4 Å²	102.4	63%	0.626	52%	0.516	S	S	*	.	H	α-helix	trans	-69.1	-41.7	175.5	-82.3	-175.3	-84.5	173.2	-5.1	112.1	K235 S236 E237 V242 Q243	K235-R239 WeakPolarHBondContact O-CG 3.49Å; K235-R239 PolarHBondContact O-NE 3.02Å; S236-R239 PolarHBondContact O-N 2.85Å; E237-R239 VanDerWaalsContact C-N 3.3Å; E237-R239 PolarHBondContact O-N 3.37Å; R239-V242 PolarHBondContact O-N 3.03Å; R239-Q243 WeakPolarHBondContact O-CG 3.44Å; R239-Q243 PolarHBondContact O-N 3.33Å
240	F	58.4	Low	63.9	Low	96 Å²	96	108 Å²	108	42%	0.421	54%	0.542	S	S	.	.	H	α-helix	trans	-72.6	-30.7	176.7	-70.5	-67.8	0	0	0	112.8	S236 E237 V242 Q243 N244 L258	S236-F240 WeakPolarHBondContact O-CD2 3.3Å; S236-F240 PolarHBondContact O-N 3.43Å; S236-F240 VanDerWaalsContact O-N 3.11Å; E237-F240 PolarHBondContact O-N 2.91Å; F240-V242 VanDerWaalsContact C-N 3.35Å; F240-Q243 PolarHBondContact O-N 2.93Å; F240-N244 WeakPolarHBondContact O-CB 3.49Å; F240-N244 VanDerWaalsContact O-CG 3.27Å; F240-N244 PolarHBondContact O-N 3.3Å; F240-N244 PolarHBondContact O-ND2 3.01Å; F240-L258 HydrophobicContact CB-CD2 4.01Å; F240-L258 HydrophobicContact CD2-CD2 3.75Å; F240-L258 HydrophobicContact CG-CD2 3.97Å
241	H	58	Low	62.2	Low	134 Å²	134	112.1 Å²	112.1	62%	0.62	57%	0.565	S	S	*	*	H	α-helix	trans	-71.8	-30.7	176.1	-147.7	-55.9	0	0	0	112.3	E237 L245	E237-H241 WeakPolarHBondContact O-CB 3.35Å; E237-H241 PolarHBondContact O-N 2.95Å; H241-L245 PolarHBondContact O-N 3.37Å; H241-L245 VanDerWaalsContact O-N 3.13Å
242	V	55.9	Low	60.6	Low	108 Å²	108	111.5 Å²	111.5	66%	0.655	58%	0.584	S	S	*	*	H	α-helix	trans	-75.3	-38.9	172.7	173.5	0	0	0	0	111.5	G238 R239 F240 L245 S246	G238-V242 VanDerWaalsContact O-CG2 3.27Å; G238-V242 WeakPolarHBondContact O-CG2 3.5Å; G238-V242 PolarHBondContact O-N 3.28Å; G238-V242 VanDerWaalsContact O-N 3.16Å; R239-V242 PolarHBondContact O-N 3.03Å; F240-V242 VanDerWaalsContact C-N 3.35Å; V242-L245 PolarHBondContact O-N 3.35Å; V242-S246 PolarHBondContact O-OG 2.81Å
243	Q	55.3	Low	59.2	Low	112 Å²	112	115.8 Å²	115.8	52%	0.523	60%	0.597	S	S	.	*	H	α-helix	trans	-71.3	-34.6	175.3	-76.5	177.6	-24.8	0	0	113	R239 F240 S246 Q247	R239-Q243 WeakPolarHBondContact O-CG 3.44Å; R239-Q243 PolarHBondContact O-N 3.33Å; F240-Q243 PolarHBondContact O-N 2.93Å; Q243-S246 PolarHBondContact O-N 2.83Å; Q243-S246 PolarHBondContact O-OG 3.24Å; Q243-S246 VanDerWaalsContact O-OG 3.1Å; Q243-Q247 PolarHBondContact O-N 3.45Å
244	N	51.2	Low	58	Low	74 Å²	74	120.3 Å²	120.3	40%	0.396	63%	0.626	S	S	.	*	H	α-helix	trans	-74.2	-29.5	175.5	-78.1	-15.6	0	0	0	111.7	F240 S246 Q247 V248	F240-N244 WeakPolarHBondContact O-CB 3.49Å; F240-N244 VanDerWaalsContact O-CG 3.27Å; F240-N244 PolarHBondContact O-N 3.3Å; F240-N244 PolarHBondContact O-ND2 3.01Å; N244-S246 PolarHBondContact O-N 2.84Å; N244-S246 VanDerWaalsContact O-N 3.15Å; N244-Q247 CarbonylContact O-C 3.6Å; N244-Q247 PolarHBondContact O-N 3.15Å; N244-V248 HydrophobicContact CB-CG2 3.7Å; N244-V248 WeakPolarHBondContact O-CB 3.35Å; N244-V248 WeakPolarHBondContact O-CG2 3.32Å; N244-V248 PolarHBondContact O-N 3.17Å
245	L	55.6	Low	56.9	Low	139 Å²	139	118.1 Å²	118.1	73%	0.728	63%	0.629	S	S	*	*	H	α-helix	trans	-61.2	-24.1	172.4	-119.5	83.5	0	0	0	112.8	H241 V242	H241-L245 PolarHBondContact O-N 3.37Å; H241-L245 VanDerWaalsContact O-N 3.13Å; V242-L245 PolarHBondContact O-N 3.35Å
246	S	51.8	Low	55.7	Low	97 Å²	97	118.7 Å²	118.7	68%	0.678	63%	0.634	S	S	*	*	T	Hydrogen-bonded Turn	trans	-95.7	-1	174.3	28.4	0	0	0	0	114.7	V242 Q243 N244	V242-S246 PolarHBondContact O-OG 2.81Å; Q243-S246 PolarHBondContact O-N 2.83Å; Q243-S246 PolarHBondContact O-OG 3.24Å; Q243-S246 VanDerWaalsContact O-OG 3.1Å; N244-S246 PolarHBondContact O-N 2.84Å; N244-S246 VanDerWaalsContact O-N 3.15Å
247	Q	51.6	Low	54.7	Low	145 Å²	145	119.4 Å²	119.4	68%	0.678	65%	0.648	S	S	*	*	T	Hydrogen-bonded Turn	trans	-130.2	-6.1	178.7	-72.3	-172.2	-19.7	0	0	115.1	Q243 N244 E249	Q243-Q247 PolarHBondContact O-N 3.45Å; N244-Q247 CarbonylContact O-C 3.6Å; N244-Q247 PolarHBondContact O-N 3.15Å; Q247-E249 PolarHBondContact O-N 3.18Å
248	V	53	Low	53.9	Low	106 Å²	106	121.2 Å²	121.2	64%	0.642	66%	0.658	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.5	2.8	-176.3	165.2	0	0	0	0	113.7	N244 Q250	N244-V248 HydrophobicContact CB-CG2 3.7Å; N244-V248 WeakPolarHBondContact O-CB 3.35Å; N244-V248 WeakPolarHBondContact O-CG2 3.32Å; N244-V248 PolarHBondContact O-N 3.17Å; V248-Q250 PolarHBondContact O-N 2.92Å
249	E	47	Very low	53.5	Low	199 Å²	199	127.8 Å²	127.8	93%	0.93	67%	0.672	S	S	*	*	T	Hydrogen-bonded Turn	trans	-74.9	-4.4	171.1	-112.9	-179.7	159.3	0	0	114.6	Q247	Q247-E249 PolarHBondContact O-N 3.18Å
250	Q	47.4	Very low	53.3	Low	174 Å²	174	128.7 Å²	128.7	81%	0.813	68%	0.676	S	S	*	*	S	Bend	trans	-134	-8.9	-171.2	-98.9	178.2	8	0	0	120.8	V248	V248-Q250 PolarHBondContact O-N 2.92Å
251	D	45.8	Very low	53.2	Low	141 Å²	141	127.6 Å²	127.6	75%	0.754	68%	0.68	S	S	*	*			trans	-158.2	108.8	172.8	-108.4	-32.1	0	0	0	115	R253	D251-R253 VanDerWaalsContact C-N 3.3Å; D251-R253 PolarHBondContact O-N 3.37Å
252	G	52	Low	53.4	Low	84 Å²	84	122.2 Å²	122.2	87%	0.866	66%	0.657	S	S	*	*	T	Hydrogen-bonded Turn	trans	-79.8	31.7	-171.3	0	0	0	0	0	116.8
253	R	54.2	Low	53.8	Low	235 Å²	235	123.1 Å²	123.1	89%	0.887	65%	0.652	S	S	*	*	T	Hydrogen-bonded Turn	trans	-129.9	1.9	-167.1	-84	-177.6	167.3	158.3	-3.4	119.5	D251	D251-R253 VanDerWaalsContact C-N 3.3Å; D251-R253 PolarHBondContact O-N 3.37Å
254	T	54.6	Low	54.3	Low	132 Å²	132	123.9 Å²	123.9	81%	0.81	65%	0.654	S	S	*	*			trans	-113.6	5.2	-170.5	51	0	0	0	0	117.1	H256	T254-H256 PolarHBondContact O-N 3.35Å
255	G	53.9	Low	55.1	Low	63 Å²	63	121 Å²	121	65%	0.649	64%	0.64	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.3	2.9	-172.3	0	0	0	0	0	118.8
256	H	54.3	Low	55.9	Low	157 Å²	157	118 Å²	118	73%	0.727	62%	0.624	S	S	*	*	H	α-helix	trans	-85.1	-26.6	-167.5	-161.1	-92.1	0	0	0	114.9	T254	T254-H256 PolarHBondContact O-N 3.35Å
257	G	54.2	Low	56.9	Low	56 Å²	56	118.6 Å²	118.6	58%	0.577	61%	0.614	S	S	*	*	H	α-helix	trans	-72	-51	-175.3	0	0	0	0	0	114.3	R259 R260	G257-R259 PolarHBondContact O-N 2.87Å; G257-R260 WeakPolarHBondContact O-CB 3.41Å; G257-R260 PolarHBondContact O-N 3.32Å
258	L	53	Low	58.1	Low	91 Å²	91	116 Å²	116	48%	0.476	60%	0.602	S	S	.	*	H	α-helix	trans	-63.8	-43.6	-176.7	-108.1	71.6	0	0	0	112.5	F240 R260 S261 S262	F240-L258 HydrophobicContact CB-CD2 4.01Å; F240-L258 HydrophobicContact CD2-CD2 3.75Å; F240-L258 HydrophobicContact CG-CD2 3.97Å; L258-R260 PolarHBondContact O-N 3.07Å; L258-R260 VanDerWaalsContact O-N 3.07Å; L258-S261 PolarHBondContact O-N 2.83Å; L258-S262 PolarHBondContact O-N 3.21Å
259	R	54.4	Low	59.4	Low	174 Å²	174	113.1 Å²	113.1	66%	0.657	58%	0.581	S	S	*	*	H	α-helix	trans	-61.6	-21.9	180	-160.4	176.4	178.7	-171	1.4	112.6	G257 K263	G257-R259 PolarHBondContact O-N 2.87Å; R259-K263 VanDerWaalsContact O-CG 3.26Å; R259-K263 WeakPolarHBondContact O-CG 3.4Å; R259-K263 PolarHBondContact O-N 3.47Å
260	R	56.9	Low	61.2	Low	186 Å²	186	110.4 Å²	110.4	70%	0.702	57%	0.567	S	S	*	*	H	α-helix	trans	-76.6	-37.6	175.9	-166.5	176.6	177.7	176.5	-2.8	111.9	G257 L258 F264	G257-R260 WeakPolarHBondContact O-CB 3.41Å; G257-R260 PolarHBondContact O-N 3.32Å; L258-R260 PolarHBondContact O-N 3.07Å; L258-R260 VanDerWaalsContact O-N 3.07Å; R260-F264 PolarHBondContact O-N 3.25Å; R260-F264 VanDerWaalsContact O-N 3.08Å
261	S	57.7	Low	63	Low	72 Å²	72	104.7 Å²	104.7	50%	0.503	55%	0.549	S	S	.	.	H	α-helix	trans	-66.3	-47	178.9	-174	0	0	0	0	112	L258 K263 F264 C265	L258-S261 PolarHBondContact O-N 2.83Å; S261-K263 PolarHBondContact O-N 3.19Å; S261-F264 WeakPolarHBondContact O-CB 3.31Å; S261-F264 PolarHBondContact O-N 2.97Å; S261-F264 VanDerWaalsContact O-N 3.1Å; S261-C265 PolarHBondContact O-N 2.98Å
262	S	62.3	Low	65.1	Low	21 Å²	21	99 Å²	99	15%	0.147	52%	0.519	C	S	.	.	H	α-helix	trans	-62.5	-40	176.7	176.6	0	0	0	0	112.6	E237 L258 F264 C265 L266	E237-S262 VanDerWaalsContact CD-CB 3.47Å; E237-S262 WeakPolarHBondContact OE1-CB 3.39Å; E237-S262 VanDerWaalsContact OE2-CB 3.32Å; E237-S262 WeakPolarHBondContact OE2-CB 3.48Å; E237-S262 PolarHBondContact OE2-OG 2.95Å; L258-S262 PolarHBondContact O-N 3.21Å; S262-F264 VanDerWaalsContact C-N 3.34Å; S262-F264 PolarHBondContact O-N 3.09Å; S262-C265 PolarHBondContact O-N 3.37Å; S262-L266 WeakPolarHBondContact O-CB 3.48Å; S262-L266 WeakPolarHBondContact O-CD1 3.47Å; S262-L266 VanDerWaalsContact O-CG 3.24Å; S262-L266 WeakPolarHBondContact O-CG 3.37Å; S262-L266 PolarHBondContact O-N 3.19Å
263	K	62.8	Low	66.9	Low	128 Å²	128	100.7 Å²	100.7	56%	0.557	50%	0.502	S	S	*	.	H	α-helix	trans	-61.1	-38.8	172.4	-76.7	178.4	-177.1	-179.7	0	113.1	R259 S261 K267	R259-K263 VanDerWaalsContact O-CG 3.26Å; R259-K263 WeakPolarHBondContact O-CG 3.4Å; R259-K263 PolarHBondContact O-N 3.47Å; S261-K263 PolarHBondContact O-N 3.19Å; K263-K267 PolarHBondContact O-N 3.11Å
264	F	66.4	Low	68.7	Low	128 Å²	128	90.1 Å²	90.1	56%	0.561	46%	0.464	S	S	*	.	H	α-helix	trans	-66.2	-50.4	177.7	-178.7	-96.6	0	0	0	111.1	R260 S261 S262 L266 K267 E268	R260-F264 PolarHBondContact O-N 3.25Å; R260-F264 VanDerWaalsContact O-N 3.08Å; S261-F264 WeakPolarHBondContact O-CB 3.31Å; S261-F264 PolarHBondContact O-N 2.97Å; S261-F264 VanDerWaalsContact O-N 3.1Å; S262-F264 VanDerWaalsContact C-N 3.34Å; S262-F264 PolarHBondContact O-N 3.09Å; F264-L266 VanDerWaalsContact C-N 3.3Å; F264-L266 PolarHBondContact O-N 2.92Å; F264-K267 WeakPolarHBondContact O-CA 3.39Å; F264-K267 WeakPolarHBondContact O-CB 3.44Å; F264-K267 PolarHBondContact O-N 2.95Å; F264-E268 HydrophobicContact CD1-CG 4.39Å; F264-E268 HydrophobicContact CE1-CG 4Å; F264-E268 WeakPolarHBondContact CE1-OE1 3.23Å; F264-E268 HydrophobicContact CZ-CG 4.21Å; F264-E268 VanDerWaalsContact CZ-OE1 3.22Å; F264-E268 WeakPolarHBondContact CZ-OE1 3.22Å; F264-E268 PolarHBondContact O-N 3.49Å
265	C	68.7	Low	70.5	Confident	13 Å²	13	84.6 Å²	84.6	9%	0.088	43%	0.429	C	S	.	.	H	α-helix	trans	-59.2	-40.4	176.6	-176.6	0	0	0	0	112.1	I233 S261 S262 K267 E268 H269	I233-C265 HydrophobicContact CD1-CB 3.72Å; I233-C265 WeakPolarHBondContact CD1-SG 3.46Å; S261-C265 PolarHBondContact O-N 2.98Å; S262-C265 PolarHBondContact O-N 3.37Å; C265-K267 VanDerWaalsContact C-N 3.33Å; C265-K267 PolarHBondContact O-N 2.99Å; C265-E268 PolarHBondContact O-N 2.68Å; C265-H269 WeakPolarHBondContact O-CB 3.39Å; C265-H269 PolarHBondContact O-N 2.83Å
266	L	71.8	Confident	72.4	Confident	77 Å²	77	82.7 Å²	82.7	40%	0.403	41%	0.41	S	S	.	.	H	α-helix	trans	-63.4	-35.8	173.9	-76	163.8	0	0	0	112.6	S262 F264 K270	S262-L266 WeakPolarHBondContact O-CB 3.48Å; S262-L266 WeakPolarHBondContact O-CD1 3.47Å; S262-L266 VanDerWaalsContact O-CG 3.24Å; S262-L266 WeakPolarHBondContact O-CG 3.37Å; S262-L266 PolarHBondContact O-N 3.19Å; F264-L266 VanDerWaalsContact C-N 3.3Å; F264-L266 PolarHBondContact O-N 2.92Å; L266-K270 VanDerWaalsContact O-CG 3.29Å; L266-K270 WeakPolarHBondContact O-CG 3.29Å; L266-K270 PolarHBondContact O-N 3.32Å; L266-K270 VanDerWaalsContact O-N 3.08Å
267	K	73.8	Confident	74.4	Confident	109 Å²	109	77.8 Å²	77.8	47%	0.474	39%	0.388	S	S	.	.	H	α-helix	trans	-65.9	-44.3	174.6	-171	-177.3	177.1	-175.1	0	110.4	K263 F264 C265 K270 A271 D331	K263-K267 PolarHBondContact O-N 3.11Å; F264-K267 WeakPolarHBondContact O-CA 3.39Å; F264-K267 WeakPolarHBondContact O-CB 3.44Å; F264-K267 PolarHBondContact O-N 2.95Å; C265-K267 VanDerWaalsContact C-N 3.33Å; C265-K267 PolarHBondContact O-N 2.99Å; K267-K270 WeakPolarHBondContact O-CB 3.17Å; K267-K270 PolarHBondContact O-N 3.09Å; K267-A271 PolarHBondContact O-N 3.35Å; K267-D331 IonicContact NZ-OD1 3.73Å; K267-D331 IonicContact NZ-OD2 2.73Å; K267-D331 PolarHBondContact NZ-OD2 3.23Å
268	E	75.7	Confident	76.3	Confident	89 Å²	89	75.2 Å²	75.2	42%	0.416	36%	0.361	S	S	.	.	H	α-helix	trans	-63.1	-43.4	177	-67.9	-170.6	146	0	0	112	F264 C265 K270 A271 L272	F264-E268 HydrophobicContact CD1-CG 4.39Å; F264-E268 HydrophobicContact CE1-CG 4Å; F264-E268 WeakPolarHBondContact CE1-OE1 3.23Å; F264-E268 HydrophobicContact CZ-CG 4.21Å; F264-E268 VanDerWaalsContact CZ-OE1 3.22Å; F264-E268 WeakPolarHBondContact CZ-OE1 3.22Å; F264-E268 PolarHBondContact O-N 3.49Å; C265-E268 PolarHBondContact O-N 2.68Å; E268-K270 VanDerWaalsContact C-N 3.29Å; E268-K270 PolarHBondContact O-N 2.74Å; E268-A271 WeakPolarHBondContact O-CB 3.41Å; E268-A271 PolarHBondContact O-N 2.82Å; E268-A271 VanDerWaalsContact O-N 3.08Å; E268-L272 PolarHBondContact O-N 2.53Å
269	H	81.1	Confident	78.4	Confident	46 Å²	46	71.3 Å²	71.3	21%	0.213	34%	0.341	C	S	.	.	H	α-helix	trans	-62.6	-36.7	176.6	-164.6	78.8	0	0	0	112.2	C265 L272 K273	C265-H269 WeakPolarHBondContact O-CB 3.39Å; C265-H269 PolarHBondContact O-N 2.83Å; H269-L272 PolarHBondContact O-N 3.12Å; H269-K273 WeakPolarHBondContact O-CB 3.45Å; H269-K273 PolarHBondContact O-N 3.25Å
270	K	84	Confident	80.4	Confident	142 Å²	142	64.5 Å²	64.5	62%	0.617	32%	0.324	S	S	*	.	H	α-helix	trans	-65.3	-39.2	172.8	-75	175.4	-176.2	-177.8	0	112.1	L266 K267 E268 K273 T274	L266-K270 VanDerWaalsContact O-CG 3.29Å; L266-K270 WeakPolarHBondContact O-CG 3.29Å; L266-K270 PolarHBondContact O-N 3.32Å; L266-K270 VanDerWaalsContact O-N 3.08Å; K267-K270 WeakPolarHBondContact O-CB 3.17Å; K267-K270 PolarHBondContact O-N 3.09Å; E268-K270 VanDerWaalsContact C-N 3.29Å; E268-K270 PolarHBondContact O-N 2.74Å; K270-K273 PolarHBondContact O-N 3.34Å; K270-T274 PolarHBondContact O-N 3.24Å; K270-T274 PolarHBondContact O-OG1 3.23Å; K270-T274 VanDerWaalsContact O-OG1 3.12Å
271	A	85.2	Confident	82.3	Confident	54 Å²	54	57.1 Å²	57.1	45%	0.446	30%	0.3	S	S	.	.	H	α-helix	trans	-64.9	-44.8	176.3	0	0	0	0	0	111.5	K267 E268 K273 T274 L275	K267-A271 PolarHBondContact O-N 3.35Å; E268-A271 WeakPolarHBondContact O-CB 3.41Å; E268-A271 PolarHBondContact O-N 2.82Å; E268-A271 VanDerWaalsContact O-N 3.08Å; A271-K273 PolarHBondContact O-N 2.97Å; A271-T274 WeakPolarHBondContact O-CB 3.22Å; A271-T274 PolarHBondContact O-N 3.13Å; A271-T274 VanDerWaalsContact O-N 3.16Å; A271-L275 PolarHBondContact O-N 3.34Å; A271-L275 VanDerWaalsContact O-N 3.07Å
272	L	89.7	Confident	84.2	Confident	22 Å²	22	53.8 Å²	53.8	12%	0.115	28%	0.276	C	S	.	.	H	α-helix	trans	-58.8	-47.1	172.2	-68.2	176.2	0	0	0	111	R131 I135 Y219 V222 A226 E268 H269 T274 L275 G276	R131-L272 HydrophobicContact CB-CD2 4.22Å; R131-L272 HydrophobicContact CG-CD2 4.18Å; I135-L272 HydrophobicContact CD1-CD1 4.07Å; Y219-L272 PolarHBondContact OH-O 2.9Å; V222-L272 HydrophobicContact CG1-CD1 4.17Å; V222-L272 HydrophobicContact CG1-CD2 3.7Å; A226-L272 HydrophobicContact CB-CD1 3.67Å; E268-L272 PolarHBondContact O-N 2.53Å; H269-L272 PolarHBondContact O-N 3.12Å; L272-T274 PolarHBondContact O-N 3.43Å; L272-L275 PolarHBondContact O-N 2.95Å; L272-L275 VanDerWaalsContact O-N 3.13Å; L272-G276 PolarHBondContact O-N 3.28Å
273	K	91.1	Very high	85.9	Confident	119 Å²	119	53.9 Å²	53.9	52%	0.517	28%	0.276	S	S	.	.	H	α-helix	trans	-55.8	-39.4	176.2	-175.7	171.3	-178.8	170.9	0	112.5	H269 K270 A271 G276 I277	H269-K273 WeakPolarHBondContact O-CB 3.45Å; H269-K273 PolarHBondContact O-N 3.25Å; K270-K273 PolarHBondContact O-N 3.34Å; A271-K273 PolarHBondContact O-N 2.97Å; K273-G276 PolarHBondContact O-N 2.86Å; K273-I277 HydrophobicContact CG-CD1 4.21Å; K273-I277 WeakPolarHBondContact O-CD1 3.22Å; K273-I277 VanDerWaalsContact O-CG1 3.25Å; K273-I277 WeakPolarHBondContact O-CG1 3.22Å; K273-I277 PolarHBondContact O-N 2.88Å
274	T	91.9	Very high	87.5	Confident	14 Å²	14	54.1 Å²	54.1	9%	0.086	28%	0.283	C	S	.	.	H	α-helix	trans	-65	-46.6	177.2	-60	0	0	0	0	111.9	K270 A271 L272 G276 I277 I278 I325 R328	K270-T274 PolarHBondContact O-N 3.24Å; K270-T274 PolarHBondContact O-OG1 3.23Å; K270-T274 VanDerWaalsContact O-OG1 3.12Å; A271-T274 WeakPolarHBondContact O-CB 3.22Å; A271-T274 PolarHBondContact O-N 3.13Å; A271-T274 VanDerWaalsContact O-N 3.16Å; L272-T274 PolarHBondContact O-N 3.43Å; T274-G276 VanDerWaalsContact C-N 3.33Å; T274-G276 PolarHBondContact O-N 2.86Å; T274-I277 WeakPolarHBondContact O-CB 3.29Å; T274-I277 PolarHBondContact O-N 3.41Å; T274-I278 WeakPolarHBondContact O-CG1 3.29Å; T274-I278 PolarHBondContact O-N 3.36Å; T274-I278 VanDerWaalsContact O-N 3.11Å; T274-I325 HydrophobicContact CG2-CG2 3.79Å; T274-R328 HydrophobicContact CG2-CB 4.35Å
275	L	91.7	Very high	89	Confident	16 Å²	16	48.5 Å²	48.5	8%	0.084	26%	0.259	C	S	.	.	H	α-helix	trans	-63	-38.7	176.2	-67.8	176.6	0	0	0	112.2	T68 I72 I127 R131 Y219 A271 L272 I277 I278 M279	T68-L275 HydrophobicContact CG2-CD1 4.18Å; I72-L275 HydrophobicContact CD1-CD2 4.32Å; I127-L275 HydrophobicContact CG2-CD1 4.09Å; I127-L275 HydrophobicContact CG2-CD2 4.14Å; R131-L275 HydrophobicContact CG-CD1 3.62Å; Y219-L275 HydrophobicContact CE2-CB 4.36Å; Y219-L275 VanDerWaalsContact OH-CB 3.27Å; Y219-L275 WeakPolarHBondContact OH-CB 3.48Å; A271-L275 PolarHBondContact O-N 3.34Å; A271-L275 VanDerWaalsContact O-N 3.07Å; L272-L275 PolarHBondContact O-N 2.95Å; L272-L275 VanDerWaalsContact O-N 3.13Å; L275-I277 VanDerWaalsContact C-N 3.31Å; L275-I277 PolarHBondContact O-N 3.32Å; L275-I278 HydrophobicContact CD2-CD1 4.26Å; L275-I278 WeakPolarHBondContact O-CB 3.47Å; L275-I278 PolarHBondContact O-N 3.37Å; L275-M279 WeakPolarHBondContact O-CG 3.48Å; L275-M279 PolarHBondContact O-N 3.15Å
276	G	94.6	Very high	90.4	Very high	23 Å²	23	48.2 Å²	48.2	24%	0.237	26%	0.256	C	S	.	.	H	α-helix	trans	-64.1	-34.5	174.3	0	0	0	0	0	113.3	Y219 L272 K273 T274 G280	Y219-G276 PolarHBondContact OH-N 3.18Å; Y219-G276 VanDerWaalsContact OH-N 3.17Å; L272-G276 PolarHBondContact O-N 3.28Å; K273-G276 PolarHBondContact O-N 2.86Å; T274-G276 VanDerWaalsContact C-N 3.33Å; T274-G276 PolarHBondContact O-N 2.86Å; G276-G280 PolarHBondContact O-N 3.37Å
277	I	95.5	Very high	91.7	Very high	53 Å²	53	47 Å²	47	27%	0.272	25%	0.25	S	S	.	.	H	α-helix	trans	-64.4	-44.6	171.9	-69	162.4	0	0	0	110	K273 T274 L275 M279 G280 T281 I325	K273-I277 HydrophobicContact CG-CD1 4.21Å; K273-I277 WeakPolarHBondContact O-CD1 3.22Å; K273-I277 VanDerWaalsContact O-CG1 3.25Å; K273-I277 WeakPolarHBondContact O-CG1 3.22Å; K273-I277 PolarHBondContact O-N 2.88Å; T274-I277 WeakPolarHBondContact O-CB 3.29Å; T274-I277 PolarHBondContact O-N 3.41Å; L275-I277 VanDerWaalsContact C-N 3.31Å; L275-I277 PolarHBondContact O-N 3.32Å; I277-M279 PolarHBondContact O-N 2.96Å; I277-G280 PolarHBondContact O-N 3.32Å; I277-T281 WeakPolarHBondContact O-CB 3.49Å; I277-T281 PolarHBondContact O-N 3.09Å; I277-T281 PolarHBondContact O-OG1 2.87Å; I277-I325 HydrophobicContact CB-CG2 4.3Å; I277-I325 HydrophobicContact CG2-CD1 4.01Å; I277-I325 HydrophobicContact CG2-CG1 4.08Å; I277-I325 HydrophobicContact CG2-CG2 3.96Å
278	I	95	Very high	92.8	Very high	3 Å²	3	44 Å²	44	2%	0.015	24%	0.242	C	C	.	.	H	α-helix	trans	-57.9	-50.1	178	-63.9	169.7	0	0	0	110.9	L75 L124 T274 L275 G280 T281 F282 I325 Y326	L75-I278 HydrophobicContact CD2-CG2 4.18Å; L124-I278 HydrophobicContact CD2-CG2 3.68Å; T274-I278 WeakPolarHBondContact O-CG1 3.29Å; T274-I278 PolarHBondContact O-N 3.36Å; T274-I278 VanDerWaalsContact O-N 3.11Å; L275-I278 HydrophobicContact CD2-CD1 4.26Å; L275-I278 WeakPolarHBondContact O-CB 3.47Å; L275-I278 PolarHBondContact O-N 3.37Å; I278-G280 VanDerWaalsContact C-N 3.35Å; I278-G280 PolarHBondContact O-N 2.9Å; I278-T281 PolarHBondContact O-N 3.12Å; I278-F282 PolarHBondContact O-N 3.28Å; I278-I325 HydrophobicContact CD1-CG2 4.23Å; I278-I325 HydrophobicContact CG1-CB 4.18Å; I278-I325 HydrophobicContact CG1-CD1 4.16Å; I278-I325 HydrophobicContact CG1-CG2 3.58Å; I278-Y326 HydrophobicContact CD1-CD1 3.98Å; I278-Y326 HydrophobicContact CD1-CE1 3.23Å
279	M	95.2	Very high	93.8	Very high	9 Å²	9	40.8 Å²	40.8	4%	0.044	23%	0.226	C	C	.	.	H	α-helix	trans	-63.2	-40.4	179.2	-65	173.4	-174.5	0	0	112.4	L124 I127 A128 M215 Y219 L275 I277 T283	L124-M279 HydrophobicContact CD2-CG 4.18Å; I127-M279 HydrophobicContact CB-CE 4.09Å; I127-M279 HydrophobicContact CG2-CE 3.69Å; A128-M279 HydrophobicContact CB-CE 3.86Å; A128-M279 HydrophobicContact CB-SD 4.29Å; M215-M279 HydrophobicContact CE-CB 4.19Å; M215-M279 HydrophobicContact CG-CG 4.25Å; M215-M279 HydrophobicContact CG-SD 3.93Å; M215-M279 HydrophobicContact SD-CB 3.82Å; M215-M279 HydrophobicContact SD-CG 3.67Å; M215-M279 HydrophobicContact SD-SD 4.16Å; Y219-M279 HydrophobicContact CD1-SD 4.02Å; Y219-M279 HydrophobicContact CD2-CE 3.53Å; Y219-M279 HydrophobicContact CD2-SD 3.22Å; Y219-M279 WeakPolarHBondContact CD2-SD 3.31Å; Y219-M279 HydrophobicContact CE1-SD 4.33Å; Y219-M279 HydrophobicContact CE2-CE 3.54Å; Y219-M279 HydrophobicContact CE2-SD 3.58Å; Y219-M279 VanDerWaalsContact CE2-SD 3.58Å; Y219-M279 HydrophobicContact CG-CE 4.37Å; Y219-M279 HydrophobicContact CG-SD 3.45Å; L275-M279 WeakPolarHBondContact O-CG 3.48Å; L275-M279 PolarHBondContact O-N 3.15Å; I277-M279 PolarHBondContact O-N 2.96Å; M279-T283 WeakPolarHBondContact O-CB 3.39Å; M279-T283 PolarHBondContact O-N 3.48Å; M279-T283 PolarHBondContact O-OG1 3.36Å
280	G	96.7	Very high	94.5	Very high	30 Å²	30	39.5 Å²	39.5	31%	0.309	22%	0.22	S	C	.	.	H	α-helix	trans	-64.5	-45.7	176.5	0	0	0	0	0	112.5	G276 I277 I278 T283 L284	G276-G280 PolarHBondContact O-N 3.37Å; I277-G280 PolarHBondContact O-N 3.32Å; I278-G280 VanDerWaalsContact C-N 3.35Å; I278-G280 PolarHBondContact O-N 2.9Å; G280-T283 PolarHBondContact O-N 3.19Å; G280-L284 WeakPolarHBondContact O-CB 3.44Å; G280-L284 VanDerWaalsContact O-CG 3.29Å; G280-L284 WeakPolarHBondContact O-CG 3.33Å; G280-L284 PolarHBondContact O-N 2.82Å
281	T	97.5	Very high	95.1	Very high	31 Å²	31	36.7 Å²	36.7	19%	0.19	21%	0.211	C	C	.	.	H	α-helix	trans	-61.7	-47.2	176.6	-56.4	0	0	0	0	110.9	I277 I278 T283 L284 C285 N318 F321	I277-T281 WeakPolarHBondContact O-CB 3.49Å; I277-T281 PolarHBondContact O-N 3.09Å; I277-T281 PolarHBondContact O-OG1 2.87Å; I278-T281 PolarHBondContact O-N 3.12Å; T281-T283 VanDerWaalsContact C-N 3.3Å; T281-T283 PolarHBondContact O-N 3.35Å; T281-L284 PolarHBondContact O-N 3.12Å; T281-C285 WeakPolarHBondContact O-CB 3.25Å; T281-C285 PolarHBondContact O-N 3.28Å; T281-C285 PolarHBondContact O-SG 3.36Å; T281-C285 VanDerWaalsContact O-SG 3.4Å; T281-N318 WeakPolarHBondContact CG2-OD1 3.46Å; T281-F321 HydrophobicContact CG2-CB 4.12Å; T281-F321 HydrophobicContact CG2-CD2 3.51Å; T281-F321 HydrophobicContact CG2-CE2 4.32Å; T281-F321 HydrophobicContact CG2-CG 4.21Å
282	F	97.2	Very high	95.5	Very high	2 Å²	2	34.9 Å²	34.9	1%	0.009	19%	0.194	C	C	.	.	H	α-helix	trans	-55.4	-47.7	175.8	-175.3	-81.2	0	0	0	111.5	I121 L124 F208 I278 C285 W286 N318	I121-F282 HydrophobicContact CB-CE1 3.61Å; I121-F282 HydrophobicContact CB-CZ 3.66Å; I121-F282 HydrophobicContact CD1-CD1 4.44Å; I121-F282 HydrophobicContact CD1-CE1 3.77Å; I121-F282 HydrophobicContact CG1-CD1 4.4Å; I121-F282 HydrophobicContact CG1-CE1 3.8Å; I121-F282 HydrophobicContact CG1-CZ 4.37Å; L124-F282 HydrophobicContact CD1-CB 3.58Å; L124-F282 HydrophobicContact CD1-CD1 3.98Å; L124-F282 HydrophobicContact CD1-CD2 3.65Å; L124-F282 HydrophobicContact CD1-CE2 4.39Å; L124-F282 HydrophobicContact CD1-CG 3.44Å; L124-F282 VanDerWaalsContact CD1-CG 3.44Å; F208-F282 HydrophobicContact CD2-CE1 4.34Å; F208-F282 AromaticContact CE2-CE1 3.91Å; F208-F282 HydrophobicContact CE2-CE1 3.91Å; I278-F282 PolarHBondContact O-N 3.28Å; F282-C285 PolarHBondContact O-N 3.35Å; F282-W286 AromaticContact CD2-CD1 3.79Å; F282-W286 HydrophobicContact CE1-CB 4.22Å; F282-W286 AromaticContact CE1-CD1 3.77Å; F282-W286 HydrophobicContact CE1-CG 4.15Å; F282-W286 AromaticContact CE2-CD1 3.47Å; F282-W286 VanDerWaalsContact CE2-CD1 3.47Å; F282-W286 HydrophobicContact CE2-CG 4.43Å; F282-W286 AromaticContact CE2-NE1 3.64Å; F282-W286 AromaticContact CZ-CD1 3.45Å; F282-W286 VanDerWaalsContact CZ-CD1 3.45Å; F282-W286 HydrophobicContact CZ-CG 4.01Å; F282-W286 AromaticContact CZ-NE1 3.89Å; F282-W286 PolarHBondContact O-N 3.49Å; F282-N318 WeakPolarHBondContact CA-OD1 3.29Å; F282-N318 WeakPolarHBondContact CD2-ND2 3.36Å; F282-N318 PolarHBondContact N-OD1 3.49Å
283	T	97.5	Very high	95.6	Very high	24 Å²	24	34.5 Å²	34.5	15%	0.147	19%	0.193	C	C	.	.	H	α-helix	trans	-60.6	-48.4	179	-56.3	0	0	0	0	111.2	L212 M279 G280 T281 C285 L287	L212-T283 HydrophobicContact CD1-CG2 3.77Å; L212-T283 WeakPolarHBondContact CD1-OG1 3.42Å; M279-T283 WeakPolarHBondContact O-CB 3.39Å; M279-T283 PolarHBondContact O-N 3.48Å; M279-T283 PolarHBondContact O-OG1 3.36Å; G280-T283 PolarHBondContact O-N 3.19Å; T281-T283 VanDerWaalsContact C-N 3.3Å; T281-T283 PolarHBondContact O-N 3.35Å; T283-C285 VanDerWaalsContact C-N 3.29Å; T283-C285 PolarHBondContact O-N 3.47Å; T283-L287 HydrophobicContact CG2-CB 4.39Å; T283-L287 HydrophobicContact CG2-CD2 4.29Å; T283-L287 WeakPolarHBondContact O-CB 3.15Å; T283-L287 PolarHBondContact O-N 2.97Å
284	L	97.9	Very high	95.7	Very high	132 Å²	132	30.6 Å²	30.6	69%	0.691	18%	0.177	S	C	*	.	H	α-helix	trans	-65.8	-31.9	-178.2	-70.5	172.3	0	0	0	112.9	G280 T281 P288	G280-L284 WeakPolarHBondContact O-CB 3.44Å; G280-L284 VanDerWaalsContact O-CG 3.29Å; G280-L284 WeakPolarHBondContact O-CG 3.33Å; G280-L284 PolarHBondContact O-N 2.82Å; T281-L284 PolarHBondContact O-N 3.12Å; L284-P288 VanDerWaalsContact O-CD 3.24Å; L284-P288 WeakPolarHBondContact O-CD 3.2Å; L284-P288 WeakPolarHBondContact O-CG 3.3Å
285	C	97.9	Very high	95.7	Very high	11 Å²	11	32.1 Å²	32.1	7%	0.074	19%	0.186	C	C	.	.	H	α-helix	trans	-77.9	-41.8	179.2	-73.3	0	0	0	0	113	T281 F282 T283 I314 N318	T281-C285 WeakPolarHBondContact O-CB 3.25Å; T281-C285 PolarHBondContact O-N 3.28Å; T281-C285 PolarHBondContact O-SG 3.36Å; T281-C285 VanDerWaalsContact O-SG 3.4Å; F282-C285 PolarHBondContact O-N 3.35Å; T283-C285 VanDerWaalsContact C-N 3.29Å; T283-C285 PolarHBondContact O-N 3.47Å; C285-I314 HydrophobicContact CB-CG2 4.15Å; C285-N318 HydrophobicContact CB-CB 3.77Å
286	W	98.2	Very high	95.6	Very high	6 Å²	6	34.6 Å²	34.6	2%	0.023	20%	0.197	C	C	.	.	H	α-helix	trans	-93.3	-31.6	-173.7	-78.8	103.5	0	0	0	114.5	M82 V117 F208 F282 P288 F289 F290 G315 Y316	M82-W286 HydrophobicContact CE-CZ2 4.34Å; V117-W286 HydrophobicContact CB-CH2 4.38Å; V117-W286 HydrophobicContact CB-CZ2 4.4Å; V117-W286 HydrophobicContact CG1-CD2 4.07Å; V117-W286 HydrophobicContact CG1-CE3 4.08Å; V117-W286 HydrophobicContact CG1-CH2 4.17Å; V117-W286 HydrophobicContact CG1-CZ2 4.15Å; V117-W286 HydrophobicContact CG1-CZ3 4.13Å; V117-W286 HydrophobicContact CG2-CH2 3.27Å; V117-W286 HydrophobicContact CG2-CZ2 3.4Å; V117-W286 VanDerWaalsContact CG2-CZ2 3.4Å; V117-W286 HydrophobicContact CG2-CZ3 3.93Å; F208-W286 HydrophobicContact CD2-CB 4.48Å; F208-W286 HydrophobicContact CE2-CB 3.58Å; F208-W286 HydrophobicContact CZ-CB 4.06Å; F282-W286 AromaticContact CD2-CD1 3.79Å; F282-W286 HydrophobicContact CE1-CB 4.22Å; F282-W286 AromaticContact CE1-CD1 3.77Å; F282-W286 HydrophobicContact CE1-CG 4.15Å; F282-W286 AromaticContact CE2-CD1 3.47Å; F282-W286 VanDerWaalsContact CE2-CD1 3.47Å; F282-W286 HydrophobicContact CE2-CG 4.43Å; F282-W286 AromaticContact CE2-NE1 3.64Å; F282-W286 AromaticContact CZ-CD1 3.45Å; F282-W286 VanDerWaalsContact CZ-CD1 3.45Å; F282-W286 HydrophobicContact CZ-CG 4.01Å; F282-W286 AromaticContact CZ-NE1 3.89Å; F282-W286 PolarHBondContact O-N 3.49Å; W286-P288 VanDerWaalsContact C-CD 3.48Å; W286-F289 HydrophobicContact CE3-CD1 4.13Å; W286-F289 HydrophobicContact CZ3-CD1 4.13Å; W286-F289 HydrophobicContact CZ3-CE1 4.49Å; W286-F289 PolarHBondContact O-N 2.81Å; W286-F289 VanDerWaalsContact O-N 3.16Å; W286-F290 HydrophobicContact CB-CD2 4.21Å; W286-F290 HydrophobicContact CB-CE2 4.3Å; W286-F290 HydrophobicContact CD2-CE2 4.36Å; W286-F290 HydrophobicContact CE3-CD2 4.29Å; W286-F290 AromaticContact CE3-CE2 3.73Å; W286-F290 HydrophobicContact CE3-CE2 3.73Å; W286-F290 HydrophobicContact CZ3-CE2 4.49Å; W286-F290 WeakPolarHBondContact O-CD2 3.47Å; W286-F290 PolarHBondContact O-N 3.5Å; W286-F290 VanDerWaalsContact O-N 3.12Å; W286-G315 VanDerWaalsContact CE2-CA 3.44Å; W286-G315 WeakPolarHBondContact CZ2-O 3.43Å; W286-G315 PolarHBondContact NE1-O 3.26Å; W286-Y316 AromaticContact CH2-CD1 3.89Å; W286-Y316 HydrophobicContact CH2-CD1 3.89Å; W286-Y316 AromaticContact CH2-CE1 4Å; W286-Y316 HydrophobicContact CH2-CE1 4Å; W286-Y316 HydrophobicContact CZ2-CD1 4.19Å
287	L	97.6	Very high	95.1	Very high	53 Å²	53	34.3 Å²	34.3	28%	0.277	19%	0.191	S	C	.	.	H	α-helix	trans	-56.6	-42.3	-176.4	-178.9	64.3	0	0	0	113.5	F208 Y209 L212 T283 F289 F290 I291	F208-L287 HydrophobicContact CE1-CD1 3.91Å; F208-L287 HydrophobicContact CZ-CB 4.2Å; F208-L287 HydrophobicContact CZ-CD1 4.32Å; Y209-L287 HydrophobicContact CE1-CD1 4.34Å; L212-L287 HydrophobicContact CD2-CD1 4.07Å; T283-L287 HydrophobicContact CG2-CB 4.39Å; T283-L287 HydrophobicContact CG2-CD2 4.29Å; T283-L287 WeakPolarHBondContact O-CB 3.15Å; T283-L287 PolarHBondContact O-N 2.97Å; L287-F289 VanDerWaalsContact C-N 3.33Å; L287-F289 PolarHBondContact O-N 2.88Å; L287-F290 PolarHBondContact O-N 2.65Å; L287-I291 HydrophobicContact CD1-CD1 4Å; L287-I291 HydrophobicContact CD1-CG1 4.06Å; L287-I291 HydrophobicContact CD2-CD1 4.42Å; L287-I291 HydrophobicContact CG-CD1 3.78Å; L287-I291 HydrophobicContact CG-CG1 4.29Å; L287-I291 VanDerWaalsContact O-CG1 3.3Å; L287-I291 WeakPolarHBondContact O-CG1 3.37Å; L287-I291 PolarHBondContact O-N 3.22Å
288	P	97.5	Very high	94.7	Very high	46 Å²	46	37.9 Å²	37.9	30%	0.299	21%	0.209	S	C	.	.	H	α-helix	trans	-57.8	-44	177.1	-26.3	36.7	0	0	0	113	L284 W286 I291 V292 L311	L284-P288 VanDerWaalsContact O-CD 3.24Å; L284-P288 WeakPolarHBondContact O-CD 3.2Å; L284-P288 WeakPolarHBondContact O-CG 3.3Å; W286-P288 VanDerWaalsContact C-CD 3.48Å; P288-I291 PolarHBondContact O-N 3.38Å; P288-V292 WeakPolarHBondContact O-CG2 3.48Å; P288-V292 PolarHBondContact O-N 3.42Å; P288-L311 HydrophobicContact CB-CD1 4.27Å; P288-L311 HydrophobicContact CB-CD2 3.88Å
289	F	96.7	Very high	94.3	Very high	20 Å²	20	43.2 Å²	43.2	9%	0.088	23%	0.234	C	C	.	.	H	α-helix	trans	-62.1	-49.4	177.7	171.7	-97.9	0	0	0	111.4	W286 L287 I291 V292 N293 Y308 L311 N312	W286-F289 HydrophobicContact CE3-CD1 4.13Å; W286-F289 HydrophobicContact CZ3-CD1 4.13Å; W286-F289 HydrophobicContact CZ3-CE1 4.49Å; W286-F289 PolarHBondContact O-N 2.81Å; W286-F289 VanDerWaalsContact O-N 3.16Å; L287-F289 VanDerWaalsContact C-N 3.33Å; L287-F289 PolarHBondContact O-N 2.88Å; F289-I291 VanDerWaalsContact C-N 3.3Å; F289-I291 PolarHBondContact O-N 2.84Å; F289-V292 PolarHBondContact O-N 2.92Å; F289-V292 VanDerWaalsContact O-N 3.17Å; F289-N293 WeakPolarHBondContact O-CB 3.13Å; F289-N293 PolarHBondContact O-N 2.91Å; F289-Y308 HydrophobicContact CE2-CD1 4.28Å; F289-Y308 HydrophobicContact CE2-CD2 4.46Å; F289-Y308 AromaticContact CE2-CE1 3.67Å; F289-Y308 HydrophobicContact CE2-CE1 3.67Å; F289-Y308 AromaticContact CE2-CE2 3.86Å; F289-Y308 HydrophobicContact CE2-CE2 3.86Å; F289-Y308 AromaticContact CE2-CZ 3.43Å; F289-Y308 VanDerWaalsContact CE2-CZ 3.43Å; F289-Y308 HydrophobicContact CZ-CE1 4.26Å; F289-Y308 HydrophobicContact CZ-CE2 4.41Å; F289-Y308 AromaticContact CZ-CZ 3.79Å; F289-Y308 WeakPolarHBondContact CZ-OH 3.37Å; F289-L311 HydrophobicContact CB-CB 4.12Å; F289-N312 HydrophobicContact CD2-CB 3.74Å; F289-N312 HydrophobicContact CE2-CB 3.74Å
290	F	96.3	Very high	93.5	Very high	19 Å²	19	46.9 Å²	46.9	8%	0.083	25%	0.254	C	S	.	.	H	α-helix	trans	-65.8	-31.5	-179.5	-81.5	-78	0	0	0	113.1	V117 F208 Y209 W286 L287 I294	V117-F290 HydrophobicContact CG1-CE2 4.15Å; V117-F290 HydrophobicContact CG1-CZ 4.16Å; F208-F290 HydrophobicContact CB-CD1 3.76Å; F208-F290 HydrophobicContact CB-CD2 4.04Å; F208-F290 HydrophobicContact CB-CE1 3.54Å; F208-F290 HydrophobicContact CB-CE2 3.84Å; F208-F290 HydrophobicContact CB-CG 4.01Å; F208-F290 HydrophobicContact CB-CZ 3.59Å; F208-F290 HydrophobicContact CD1-CB 3.62Å; F208-F290 AromaticContact CD1-CD1 3.94Å; F208-F290 HydrophobicContact CD1-CD1 3.94Å; F208-F290 AromaticContact CD1-CD2 3.54Å; F208-F290 HydrophobicContact CD1-CD2 3.54Å; F208-F290 HydrophobicContact CD1-CE2 4.18Å; F208-F290 AromaticContact CD1-CG 3.41Å; F208-F290 HydrophobicContact CD1-CG 3.41Å; F208-F290 VanDerWaalsContact CD1-CG 3.41Å; F208-F290 AromaticContact CD2-CD2 3.39Å; F208-F290 HydrophobicContact CD2-CD2 3.39Å; F208-F290 AromaticContact CD2-CE2 3.3Å; F208-F290 HydrophobicContact CD2-CE2 3.3Å; F208-F290 HydrophobicContact CD2-CG 4.1Å; F208-F290 AromaticContact CD2-CZ 3.94Å; F208-F290 HydrophobicContact CD2-CZ 3.94Å; F208-F290 HydrophobicContact CE1-CB 3.66Å; F208-F290 AromaticContact CE1-CD2 3.71Å; F208-F290 HydrophobicContact CE1-CD2 3.71Å; F208-F290 AromaticContact CE1-CG 3.8Å; F208-F290 HydrophobicContact CE1-CG 3.8Å; F208-F290 AromaticContact CE2-CD2 3.57Å; F208-F290 HydrophobicContact CE2-CD2 3.57Å; F208-F290 AromaticContact CE2-CE2 3.81Å; F208-F290 HydrophobicContact CE2-CE2 3.81Å; F208-F290 HydrophobicContact CE2-CG 4.43Å; F208-F290 HydrophobicContact CG-CB 4.3Å; F208-F290 AromaticContact CG-CD1 3.88Å; F208-F290 HydrophobicContact CG-CD1 3.88Å; F208-F290 AromaticContact CG-CD2 3.36Å; F208-F290 HydrophobicContact CG-CD2 3.36Å; F208-F290 HydrophobicContact CG-CE1 4Å; F208-F290 AromaticContact CG-CE2 3.51Å; F208-F290 HydrophobicContact CG-CE2 3.51Å; F208-F290 AromaticContact CG-CG 3.57Å; F208-F290 HydrophobicContact CG-CG 3.57Å; F208-F290 AromaticContact CG-CZ 3.83Å; F208-F290 HydrophobicContact CG-CZ 3.83Å; F208-F290 HydrophobicContact CZ-CB 4.38Å; F208-F290 AromaticContact CZ-CD2 3.73Å; F208-F290 HydrophobicContact CZ-CD2 3.73Å; F208-F290 HydrophobicContact CZ-CE2 4.43Å; F208-F290 HydrophobicContact CZ-CG 4.3Å; Y209-F290 HydrophobicContact CE2-CB 4.38Å; Y209-F290 PolarHBondContact OH-O 3.01Å; W286-F290 HydrophobicContact CB-CD2 4.21Å; W286-F290 HydrophobicContact CB-CE2 4.3Å; W286-F290 HydrophobicContact CD2-CE2 4.36Å; W286-F290 HydrophobicContact CE3-CD2 4.29Å; W286-F290 AromaticContact CE3-CE2 3.73Å; W286-F290 HydrophobicContact CE3-CE2 3.73Å; W286-F290 HydrophobicContact CZ3-CE2 4.49Å; W286-F290 WeakPolarHBondContact O-CD2 3.47Å; W286-F290 PolarHBondContact O-N 3.5Å; W286-F290 VanDerWaalsContact O-N 3.12Å; L287-F290 PolarHBondContact O-N 2.65Å; F290-I294 WeakPolarHBondContact O-CG1 3.4Å; F290-I294 PolarHBondContact O-N 3.49Å
291	I	95.6	Very high	92.6	Very high	83 Å²	83	51.9 Å²	51.9	43%	0.426	27%	0.273	S	S	.	.	H	α-helix	trans	-64.1	-50.8	171.7	-71.9	169.5	0	0	0	109.7	Y209 L287 P288 F289 N293 I294 V295	Y209-I291 PolarHBondContact OH-N 2.66Å; L287-I291 HydrophobicContact CD1-CD1 4Å; L287-I291 HydrophobicContact CD1-CG1 4.06Å; L287-I291 HydrophobicContact CD2-CD1 4.42Å; L287-I291 HydrophobicContact CG-CD1 3.78Å; L287-I291 HydrophobicContact CG-CG1 4.29Å; L287-I291 VanDerWaalsContact O-CG1 3.3Å; L287-I291 WeakPolarHBondContact O-CG1 3.37Å; L287-I291 PolarHBondContact O-N 3.22Å; P288-I291 PolarHBondContact O-N 3.38Å; F289-I291 VanDerWaalsContact C-N 3.3Å; F289-I291 PolarHBondContact O-N 2.84Å; I291-N293 VanDerWaalsContact C-N 3.28Å; I291-N293 PolarHBondContact O-N 2.71Å; I291-I294 PolarHBondContact O-N 3.07Å; I291-V295 HydrophobicContact CG2-CG2 4.29Å; I291-V295 WeakPolarHBondContact O-CG2 3.34Å; I291-V295 PolarHBondContact O-N 3.2Å
292	V	94.3	Very high	92.2	Very high	16 Å²	16	55.9 Å²	55.9	10%	0.097	29%	0.293	C	S	.	.	H	α-helix	trans	-60.6	-38.9	179.3	164.7	0	0	0	0	111.6	P288 F289 I294 V295 H296 I303 Y308 L311	P288-V292 WeakPolarHBondContact O-CG2 3.48Å; P288-V292 PolarHBondContact O-N 3.42Å; F289-V292 PolarHBondContact O-N 2.92Å; F289-V292 VanDerWaalsContact O-N 3.17Å; V292-I294 PolarHBondContact O-N 3.15Å; V292-V295 PolarHBondContact O-N 3.31Å; V292-H296 WeakPolarHBondContact O-CB 3.4Å; V292-H296 PolarHBondContact O-N 2.73Å; V292-I303 HydrophobicContact CB-CD1 4Å; V292-I303 HydrophobicContact CG1-CB 4.36Å; V292-I303 HydrophobicContact CG1-CD1 3.62Å; V292-I303 HydrophobicContact CG1-CG2 3.97Å; V292-I303 HydrophobicContact CG2-CD1 3.6Å; V292-Y308 HydrophobicContact CG1-CD2 3.83Å; V292-Y308 HydrophobicContact CG1-CE2 4.48Å; V292-L311 HydrophobicContact CB-CD1 4.03Å; V292-L311 HydrophobicContact CG1-CD1 4.5Å; V292-L311 HydrophobicContact CG2-CD1 3.4Å
293	N	92.9	Very high	91.7	Very high	14 Å²	14	57.9 Å²	57.9	8%	0.075	30%	0.304	C	S	.	.	H	α-helix	trans	-58.6	-45.5	175.7	-169.6	47.7	0	0	0	111.8	S204 F289 I291 H296 V297 Y308	S204-N293 PolarHBondContact OG-ND2 3.16Å; F289-N293 WeakPolarHBondContact O-CB 3.13Å; F289-N293 PolarHBondContact O-N 2.91Å; I291-N293 VanDerWaalsContact C-N 3.28Å; I291-N293 PolarHBondContact O-N 2.71Å; N293-H296 PolarHBondContact O-N 2.62Å; N293-V297 WeakPolarHBondContact O-CG2 3.46Å; N293-V297 PolarHBondContact O-N 3.07Å; N293-Y308 PolarHBondContact OD1-OH 3.46Å
294	I	92.6	Very high	91.5	Very high	38 Å²	38	65.1 Å²	65.1	20%	0.195	33%	0.328	C	S	.	.	H	α-helix	trans	-67.8	-40.7	176	-63.9	-59.8	0	0	0	111.8	I201 Y209 F290 I291 V292 H296 V297 I298	I201-I294 HydrophobicContact CG1-CD1 4.39Å; Y209-I294 HydrophobicContact CE2-CD1 4.2Å; Y209-I294 HydrophobicContact CE2-CG1 3.73Å; F290-I294 WeakPolarHBondContact O-CG1 3.4Å; F290-I294 PolarHBondContact O-N 3.49Å; I291-I294 PolarHBondContact O-N 3.07Å; V292-I294 PolarHBondContact O-N 3.15Å; I294-H296 VanDerWaalsContact C-N 3.33Å; I294-H296 PolarHBondContact O-N 3.34Å; I294-V297 WeakPolarHBondContact O-CB 3.37Å; I294-V297 PolarHBondContact O-N 3.43Å; I294-I298 HydrophobicContact CG2-CD1 4.06Å; I294-I298 WeakPolarHBondContact O-CG1 3.38Å; I294-I298 PolarHBondContact O-N 3.08Å
295	V	92.4	Very high	91	Very high	46 Å²	46	64 Å²	64	28%	0.279	32%	0.317	S	S	.	.	H	α-helix	trans	-61.9	-42.9	177.8	170.2	0	0	0	0	111.1	I291 V292 V297 I298 Q299 L302 I303	I291-V295 HydrophobicContact CG2-CG2 4.29Å; I291-V295 WeakPolarHBondContact O-CG2 3.34Å; I291-V295 PolarHBondContact O-N 3.2Å; V292-V295 PolarHBondContact O-N 3.31Å; V295-V297 VanDerWaalsContact C-N 3.25Å; V295-V297 PolarHBondContact O-N 2.97Å; V295-I298 PolarHBondContact O-N 3.37Å; V295-I298 VanDerWaalsContact O-N 3.12Å; V295-Q299 PolarHBondContact O-N 2.82Å; V295-L302 HydrophobicContact CG1-CD2 3.83Å; V295-I303 HydrophobicContact CB-CD1 4.44Å; V295-I303 HydrophobicContact CG1-CD1 4.04Å
296	H	87.6	Confident	90.7	Very high	67 Å²	67	69.1 Å²	69.1	31%	0.31	34%	0.341	S	S	.	.	H	α-helix	trans	-62.8	-33.2	179.3	-168.7	55	0	0	0	112.3	V292 N293 I294 Q299 D300	V292-H296 WeakPolarHBondContact O-CB 3.4Å; V292-H296 PolarHBondContact O-N 2.73Å; N293-H296 PolarHBondContact O-N 2.62Å; I294-H296 VanDerWaalsContact C-N 3.33Å; I294-H296 PolarHBondContact O-N 3.34Å; H296-Q299 CarbonylContact O-C 3.37Å; H296-D300 IonicContact CE1-OD1 3.07Å; H296-D300 PolarHBondContact CE1-OD1 2.03Å; H296-D300 IonicContact ND1-OD1 3.85Å; H296-D300 IonicContact NE2-OD1 3.83Å; H296-D300 PolarHBondContact O-N 2.87Å
297	V	85.5	Confident	90.5	Very high	17 Å²	17	71 Å²	71	10%	0.103	35%	0.353	C	S	.	.	H	α-helix	trans	-67.4	-39.1	173.8	171.9	0	0	0	0	112.5	Q197 A200 I201 N293 I294 V295	Q197-V297 HydrophobicContact CB-CG1 3.62Å; Q197-V297 HydrophobicContact CG-CG1 3.81Å; Q197-V297 PolarHBondContact NE2-O 2.86Å; A200-V297 HydrophobicContact CB-CG2 3.3Å; I201-V297 HydrophobicContact CD1-CG1 3.74Å; I201-V297 HydrophobicContact CG1-CG1 3.81Å; N293-V297 WeakPolarHBondContact O-CG2 3.46Å; N293-V297 PolarHBondContact O-N 3.07Å; I294-V297 WeakPolarHBondContact O-CB 3.37Å; I294-V297 PolarHBondContact O-N 3.43Å; V295-V297 VanDerWaalsContact C-N 3.25Å; V295-V297 PolarHBondContact O-N 2.97Å
298	I	86.5	Confident	90.3	Very high	129 Å²	129	70.9 Å²	70.9	66%	0.662	35%	0.349	S	S	*	.	H	α-helix	trans	-76.4	-42.6	-179.3	-63.6	169.5	0	0	0	110.7	I294 V295	I294-I298 HydrophobicContact CG2-CD1 4.06Å; I294-I298 WeakPolarHBondContact O-CG1 3.38Å; I294-I298 PolarHBondContact O-N 3.08Å; V295-I298 PolarHBondContact O-N 3.37Å; V295-I298 VanDerWaalsContact O-N 3.12Å
299	Q	86.6	Confident	90.1	Very high	115 Å²	115	71.4 Å²	71.4	54%	0.537	35%	0.348	S	S	.	.	S	Bend	trans	-136.3	102.7	-177.7	-176.6	64.3	44.2	0	0	109.5	V295 H296 L302	V295-Q299 PolarHBondContact O-N 2.82Å; H296-Q299 CarbonylContact O-C 3.37Å; Q299-L302 HydrophobicContact CG-CB 4.04Å; Q299-L302 HydrophobicContact CG-CD2 4.44Å
300	D	78.8	Confident	90.1	Very high	85 Å²	85	75.4 Å²	75.4	46%	0.455	37%	0.37	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.5	151.3	175.9	-165.9	12.7	0	0	0	110.9	H296 L302	H296-D300 IonicContact CE1-OD1 3.07Å; H296-D300 PolarHBondContact CE1-OD1 2.03Å; H296-D300 IonicContact ND1-OD1 3.85Å; H296-D300 IonicContact NE2-OD1 3.83Å; H296-D300 PolarHBondContact O-N 2.87Å; D300-L302 PolarHBondContact O-N 2.85Å; D300-L302 VanDerWaalsContact O-N 3.12Å
301	N	78.5	Confident	90.1	Very high	135 Å²	135	75.8 Å²	75.8	72%	0.722	37%	0.373	S	S	*	.	T	Hydrogen-bonded Turn	trans	60.7	13.9	177	-58.7	-63.4	0	0	0	116.9
302	L	87.6	Confident	90.2	Very high	116 Å²	116	73 Å²	73	61%	0.607	36%	0.359	S	S	*	.	S	Bend	trans	-73	-32.6	174.5	-173.7	62.6	0	0	0	112.7	V295 Q299 D300	V295-L302 HydrophobicContact CG1-CD2 3.83Å; Q299-L302 HydrophobicContact CG-CB 4.04Å; Q299-L302 HydrophobicContact CG-CD2 4.44Å; D300-L302 PolarHBondContact O-N 2.85Å; D300-L302 VanDerWaalsContact O-N 3.12Å
303	I	88.4	Confident	90.4	Very high	44 Å²	44	73.4 Å²	73.4	23%	0.226	36%	0.359	C	S	.	.	S	Bend	trans	-119.5	128	-172.9	-62.1	172.7	0	0	0	108.5	V292 V295 V307	V292-I303 HydrophobicContact CB-CD1 4Å; V292-I303 HydrophobicContact CG1-CB 4.36Å; V292-I303 HydrophobicContact CG1-CD1 3.62Å; V292-I303 HydrophobicContact CG1-CG2 3.97Å; V292-I303 HydrophobicContact CG2-CD1 3.6Å; V295-I303 HydrophobicContact CB-CD1 4.44Å; V295-I303 HydrophobicContact CG1-CD1 4.04Å; I303-V307 HydrophobicContact CG2-CB 3.8Å; I303-V307 HydrophobicContact CG2-CG1 3.81Å
304	R	91.8	Very high	90.6	Very high	175 Å²	175	75.9 Å²	75.9	66%	0.66	37%	0.372	S	S	*	.			trans	-65.6	147.4	-178.1	-57	-177.6	-70.2	157.8	0.1	111.6	E306 V307 Y308	R304-E306 VanDerWaalsContact CB-OE2 3.23Å; R304-E306 WeakPolarHBondContact CB-OE2 3.3Å; R304-E306 PolarHBondContact O-N 3.46Å; R304-V307 HydrophobicContact CB-CG2 4.44Å; R304-V307 WeakPolarHBondContact O-CB 3.32Å; R304-V307 PolarHBondContact O-N 3.48Å; R304-Y308 PolarHBondContact O-N 2.92Å
305	K	88.9	Confident	90.9	Very high	108 Å²	108	74.1 Å²	74.1	47%	0.47	36%	0.362	S	S	.	.	H	α-helix	trans	-54.3	-37.5	179.5	-174.4	174.2	180	174	0	112.4	D192 V307 Y308 I309	D192-K305 IonicContact OD1-NZ 3.58Å; D192-K305 PolarHBondContact OD1-NZ 2.77Å; D192-K305 IonicContact OD2-NZ 3.13Å; D192-K305 PolarHBondContact OD2-NZ 3.49Å; K305-V307 VanDerWaalsContact C-N 3.29Å; K305-V307 PolarHBondContact O-N 2.93Å; K305-Y308 WeakPolarHBondContact O-CB 3.42Å; K305-Y308 PolarHBondContact O-N 3.42Å; K305-I309 HydrophobicContact CG-CD1 3.95Å; K305-I309 HydrophobicContact CG-CG1 4.46Å; K305-I309 WeakPolarHBondContact O-CG1 3.35Å; K305-I309 PolarHBondContact O-N 3.46Å
306	E	90.7	Very high	91.1	Very high	120 Å²	120	72 Å²	72	56%	0.561	35%	0.349	S	S	*	.	H	α-helix	trans	-65.2	-34.6	179.6	-53.8	75.5	-157.2	0	0	112	R304 L310	R304-E306 VanDerWaalsContact CB-OE2 3.23Å; R304-E306 WeakPolarHBondContact CB-OE2 3.3Å; R304-E306 PolarHBondContact O-N 3.46Å; E306-L310 VanDerWaalsContact O-CB 3.23Å; E306-L310 WeakPolarHBondContact O-CB 3.19Å; E306-L310 PolarHBondContact O-N 3.12Å
307	V	94.3	Very high	91.6	Very high	46 Å²	46	70.8 Å²	70.8	28%	0.279	35%	0.346	S	S	.	.	H	α-helix	trans	-71.1	-42.8	176.7	179.3	0	0	0	0	110	I303 R304 K305 I309 L310 L311	I303-V307 HydrophobicContact CG2-CB 3.8Å; I303-V307 HydrophobicContact CG2-CG1 3.81Å; R304-V307 HydrophobicContact CB-CG2 4.44Å; R304-V307 WeakPolarHBondContact O-CB 3.32Å; R304-V307 PolarHBondContact O-N 3.48Å; K305-V307 VanDerWaalsContact C-N 3.29Å; K305-V307 PolarHBondContact O-N 2.93Å; V307-I309 PolarHBondContact O-N 3.22Å; V307-L310 PolarHBondContact O-N 2.95Å; V307-L311 HydrophobicContact CG1-CD1 4.19Å; V307-L311 HydrophobicContact CG1-CG 4.31Å; V307-L311 VanDerWaalsContact O-CG 3.31Å; V307-L311 WeakPolarHBondContact O-CG 3.48Å; V307-L311 PolarHBondContact O-N 3.49Å
308	Y	92.9	Very high	92.2	Very high	49 Å²	49	70 Å²	70	19%	0.192	34%	0.341	C	S	.	.	H	α-helix	trans	-57.6	-49	176.3	-173	-89.3	0	0	0	111.4	F289 V292 N293 R304 K305 L311 N312	F289-Y308 HydrophobicContact CE2-CD1 4.28Å; F289-Y308 HydrophobicContact CE2-CD2 4.46Å; F289-Y308 AromaticContact CE2-CE1 3.67Å; F289-Y308 HydrophobicContact CE2-CE1 3.67Å; F289-Y308 AromaticContact CE2-CE2 3.86Å; F289-Y308 HydrophobicContact CE2-CE2 3.86Å; F289-Y308 AromaticContact CE2-CZ 3.43Å; F289-Y308 VanDerWaalsContact CE2-CZ 3.43Å; F289-Y308 HydrophobicContact CZ-CE1 4.26Å; F289-Y308 HydrophobicContact CZ-CE2 4.41Å; F289-Y308 AromaticContact CZ-CZ 3.79Å; F289-Y308 WeakPolarHBondContact CZ-OH 3.37Å; V292-Y308 HydrophobicContact CG1-CD2 3.83Å; V292-Y308 HydrophobicContact CG1-CE2 4.48Å; N293-Y308 PolarHBondContact OD1-OH 3.46Å; R304-Y308 PolarHBondContact O-N 2.92Å; K305-Y308 WeakPolarHBondContact O-CB 3.42Å; K305-Y308 PolarHBondContact O-N 3.42Å; Y308-L311 PolarHBondContact O-N 3.02Å; Y308-N312 PolarHBondContact O-N 3.01Å; Y308-N312 VanDerWaalsContact O-N 3.11Å
309	I	94.1	Very high	92.7	Very high	57 Å²	57	64 Å²	64	29%	0.292	31%	0.311	S	S	.	.	H	α-helix	trans	-61.3	-48.9	176.1	-67.1	171.1	0	0	0	110.3	I94 K305 V307 L311 N312 W313	I94-I309 HydrophobicContact CD1-CG2 3.54Å; I94-I309 HydrophobicContact CG1-CG2 4.39Å; K305-I309 HydrophobicContact CG-CD1 3.95Å; K305-I309 HydrophobicContact CG-CG1 4.46Å; K305-I309 WeakPolarHBondContact O-CG1 3.35Å; K305-I309 PolarHBondContact O-N 3.46Å; V307-I309 PolarHBondContact O-N 3.22Å; I309-L311 VanDerWaalsContact C-N 3.33Å; I309-L311 PolarHBondContact O-N 3.28Å; I309-N312 WeakPolarHBondContact O-CB 3.02Å; I309-N312 PolarHBondContact O-N 3.06Å; I309-N312 VanDerWaalsContact O-N 3.13Å; I309-W313 VanDerWaalsContact O-CD1 3.23Å; I309-W313 PolarHBondContact O-N 3.33Å
310	L	95.9	Very high	93.1	Very high	105 Å²	105	59.1 Å²	59.1	55%	0.55	29%	0.292	S	S	.	.	H	α-helix	trans	-56.4	-46.2	-179.7	178	66	0	0	0	112.2	E306 V307 N312 W313 I314	E306-L310 VanDerWaalsContact O-CB 3.23Å; E306-L310 WeakPolarHBondContact O-CB 3.19Å; E306-L310 PolarHBondContact O-N 3.12Å; V307-L310 PolarHBondContact O-N 2.95Å; L310-N312 VanDerWaalsContact C-N 3.32Å; L310-N312 PolarHBondContact O-N 2.96Å; L310-W313 PolarHBondContact O-N 3.33Å; L310-I314 WeakPolarHBondContact O-CG1 3.03Å; L310-I314 PolarHBondContact O-N 3.46Å
311	L	97.3	Very high	94	Very high	27 Å²	27	58.7 Å²	58.7	14%	0.141	29%	0.286	C	S	.	.	H	α-helix	trans	-65	-36.7	179	-66.2	-178.4	0	0	0	112.1	P288 F289 V292 V307 Y308 I309 W313 I314 G315	P288-L311 HydrophobicContact CB-CD1 4.27Å; P288-L311 HydrophobicContact CB-CD2 3.88Å; F289-L311 HydrophobicContact CB-CB 4.12Å; V292-L311 HydrophobicContact CB-CD1 4.03Å; V292-L311 HydrophobicContact CG1-CD1 4.5Å; V292-L311 HydrophobicContact CG2-CD1 3.4Å; V307-L311 HydrophobicContact CG1-CD1 4.19Å; V307-L311 HydrophobicContact CG1-CG 4.31Å; V307-L311 VanDerWaalsContact O-CG 3.31Å; V307-L311 WeakPolarHBondContact O-CG 3.48Å; V307-L311 PolarHBondContact O-N 3.49Å; Y308-L311 PolarHBondContact O-N 3.02Å; I309-L311 VanDerWaalsContact C-N 3.33Å; I309-L311 PolarHBondContact O-N 3.28Å; L311-W313 VanDerWaalsContact C-N 3.34Å; L311-I314 HydrophobicContact CD2-CD1 4.02Å; L311-I314 PolarHBondContact O-N 2.88Å; L311-G315 PolarHBondContact O-N 3.45Å
312	N	97.1	Very high	94.8	Very high	23 Å²	23	52.3 Å²	52.3	12%	0.123	25%	0.252	C	S	.	.	H	α-helix	trans	-63	-42	173.6	-165.7	30.5	0	0	0	111.5	F289 Y308 I309 L310 I314 G315 Y316	F289-N312 HydrophobicContact CD2-CB 3.74Å; F289-N312 HydrophobicContact CE2-CB 3.74Å; Y308-N312 PolarHBondContact O-N 3.01Å; Y308-N312 VanDerWaalsContact O-N 3.11Å; I309-N312 WeakPolarHBondContact O-CB 3.02Å; I309-N312 PolarHBondContact O-N 3.06Å; I309-N312 VanDerWaalsContact O-N 3.13Å; L310-N312 VanDerWaalsContact C-N 3.32Å; L310-N312 PolarHBondContact O-N 2.96Å; N312-I314 VanDerWaalsContact C-N 3.34Å; N312-I314 PolarHBondContact O-N 2.86Å; N312-G315 CarbonylContact O-C 3.58Å; N312-G315 VanDerWaalsContact O-CA 3.3Å; N312-G315 WeakPolarHBondContact O-CA 3.49Å; N312-G315 PolarHBondContact O-N 3.44Å; N312-Y316 VanDerWaalsContact ND2-CZ 3.29Å; N312-Y316 PolarHBondContact ND2-OH 2.79Å; N312-Y316 PolarHBondContact O-N 3.03Å
313	W	97.7	Very high	95.1	Very high	25 Å²	25	47.2 Å²	47.2	10%	0.095	23%	0.226	C	C	.	.	H	α-helix	trans	-65.7	-32.9	176.1	-84.7	77.6	0	0	0	113.6	M40 V87 A91 I94 I309 L310 L311 G315 Y316 V317	M40-W313 HydrophobicContact CB-CH2 4.18Å; M40-W313 HydrophobicContact CB-CZ3 4.24Å; M40-W313 HydrophobicContact CE-CD2 4.36Å; M40-W313 HydrophobicContact CE-CE3 4.39Å; M40-W313 HydrophobicContact CE-CH2 3.63Å; M40-W313 HydrophobicContact CE-CZ2 3.59Å; M40-W313 HydrophobicContact CE-CZ3 4.05Å; M40-W313 HydrophobicContact CG-CH2 3.61Å; M40-W313 HydrophobicContact CG-CZ3 3.64Å; M40-W313 HydrophobicContact SD-CH2 3.51Å; M40-W313 VanDerWaalsContact SD-CH2 3.51Å; M40-W313 HydrophobicContact SD-CZ2 3.92Å; M40-W313 HydrophobicContact SD-CZ3 4.13Å; V87-W313 HydrophobicContact CG1-CH2 4.03Å; V87-W313 HydrophobicContact CG1-CZ3 3.89Å; A91-W313 HydrophobicContact CB-CH2 3.83Å; A91-W313 HydrophobicContact CB-CZ2 4.34Å; I94-W313 HydrophobicContact CD1-CZ2 3.73Å; I309-W313 VanDerWaalsContact O-CD1 3.23Å; I309-W313 PolarHBondContact O-N 3.33Å; L310-W313 PolarHBondContact O-N 3.33Å; L311-W313 VanDerWaalsContact C-N 3.34Å; W313-G315 PolarHBondContact O-N 3.33Å; W313-Y316 HydrophobicContact CD2-CD2 4.09Å; W313-Y316 HydrophobicContact CE3-CD2 4.44Å; W313-Y316 HydrophobicContact CG-CD2 4.23Å; W313-Y316 PolarHBondContact O-N 2.93Å; W313-V317 VanDerWaalsContact O-CG2 3.29Å; W313-V317 WeakPolarHBondContact O-CG2 3.01Å; W313-V317 PolarHBondContact O-N 2.04Å
314	I	97.9	Very high	95.5	Very high	67 Å²	67	50.9 Å²	50.9	34%	0.344	25%	0.245	S	C	.	.	H	α-helix	trans	-60.5	-39.5	169.9	-66.5	171.4	0	0	0	110.3	C285 L310 L311 N312 V317 N318	C285-I314 HydrophobicContact CB-CG2 4.15Å; L310-I314 WeakPolarHBondContact O-CG1 3.03Å; L310-I314 PolarHBondContact O-N 3.46Å; L311-I314 HydrophobicContact CD2-CD1 4.02Å; L311-I314 PolarHBondContact O-N 2.88Å; N312-I314 VanDerWaalsContact C-N 3.34Å; N312-I314 PolarHBondContact O-N 2.86Å; I314-V317 PolarHBondContact O-N 2.99Å; I314-N318 PolarHBondContact O-N 3.41Å
315	G	97.8	Very high	95.7	Very high	0 Å²	0	43.4 Å²	43.4	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-58.4	-48.5	170.5	0	0	0	0	0	112.5	W286 L311 N312 W313 V317 N318	W286-G315 VanDerWaalsContact CE2-CA 3.44Å; W286-G315 WeakPolarHBondContact CZ2-O 3.43Å; W286-G315 PolarHBondContact NE1-O 3.26Å; L311-G315 PolarHBondContact O-N 3.45Å; N312-G315 CarbonylContact O-C 3.58Å; N312-G315 VanDerWaalsContact O-CA 3.3Å; N312-G315 WeakPolarHBondContact O-CA 3.49Å; N312-G315 PolarHBondContact O-N 3.44Å; W313-G315 PolarHBondContact O-N 3.33Å; G315-V317 PolarHBondContact O-N 3.36Å; G315-N318 WeakPolarHBondContact O-CB 3.41Å; G315-N318 PolarHBondContact O-N 3.02Å
316	Y	97.9	Very high	95.9	Very high	2 Å²	2	38.5 Å²	38.5	1%	0.008	20%	0.197	C	C	.	.	H	α-helix	trans	-62.8	-39.5	178.5	-63.3	-18.5	0	0	0	113.6	M82 V86 V87 D113 W286 N312 W313 N318 S319	M82-Y316 HydrophobicContact CE-CD1 3.27Å; M82-Y316 HydrophobicContact CE-CE1 3.51Å; M82-Y316 HydrophobicContact CE-CG 4.3Å; V86-Y316 HydrophobicContact CG1-CE1 4.07Å; V87-Y316 HydrophobicContact CG2-CD2 4.32Å; V87-Y316 HydrophobicContact CG2-CG 4.18Å; D113-Y316 WeakPolarHBondContact OD1-CE1 3.4Å; D113-Y316 PolarHBondContact OD2-OH 3.4Å; W286-Y316 AromaticContact CH2-CD1 3.89Å; W286-Y316 HydrophobicContact CH2-CD1 3.89Å; W286-Y316 AromaticContact CH2-CE1 4Å; W286-Y316 HydrophobicContact CH2-CE1 4Å; W286-Y316 HydrophobicContact CZ2-CD1 4.19Å; N312-Y316 VanDerWaalsContact ND2-CZ 3.29Å; N312-Y316 PolarHBondContact ND2-OH 2.79Å; N312-Y316 PolarHBondContact O-N 3.03Å; W313-Y316 HydrophobicContact CD2-CD2 4.09Å; W313-Y316 HydrophobicContact CE3-CD2 4.44Å; W313-Y316 HydrophobicContact CG-CD2 4.23Å; W313-Y316 PolarHBondContact O-N 2.93Å; Y316-N318 PolarHBondContact O-N 2.93Å; Y316-S319 WeakPolarHBondContact O-CB 3.45Å; Y316-S319 PolarHBondContact O-N 3.1Å; Y316-S319 VanDerWaalsContact O-N 3.16Å
317	V	97.1	Very high	96	Very high	41 Å²	41	35.5 Å²	35.5	25%	0.248	19%	0.188	C	C	.	.	H	α-helix	trans	-62.3	-25.5	178.7	172.5	0	0	0	0	111.6	I43 W313 I314 G315 S319 G320 F321	I43-V317 HydrophobicContact CD1-CG2 3.91Å; I43-V317 HydrophobicContact CG1-CG2 4.39Å; I43-V317 HydrophobicContact CG2-CG2 4.21Å; W313-V317 VanDerWaalsContact O-CG2 3.29Å; W313-V317 WeakPolarHBondContact O-CG2 3.01Å; W313-V317 PolarHBondContact O-N 2.04Å; I314-V317 PolarHBondContact O-N 2.99Å; G315-V317 PolarHBondContact O-N 3.36Å; V317-S319 PolarHBondContact O-N 2.71Å; V317-G320 PolarHBondContact O-N 3.09Å; V317-F321 HydrophobicContact CG1-CE1 3.86Å; V317-F321 HydrophobicContact CG1-CE2 3.93Å; V317-F321 HydrophobicContact CG1-CZ 3.44Å; V317-F321 VanDerWaalsContact CG1-CZ 3.44Å
318	N	97.7	Very high	95.9	Very high	0 Å²	0	39.4 Å²	39.4	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-54.4	-35.8	175	-179.4	72	0	0	0	113.2	T281 F282 C285 I314 G315 Y316 G320 F321	T281-N318 WeakPolarHBondContact CG2-OD1 3.46Å; F282-N318 WeakPolarHBondContact CA-OD1 3.29Å; F282-N318 WeakPolarHBondContact CD2-ND2 3.36Å; F282-N318 PolarHBondContact N-OD1 3.49Å; C285-N318 HydrophobicContact CB-CB 3.77Å; I314-N318 PolarHBondContact O-N 3.41Å; G315-N318 WeakPolarHBondContact O-CB 3.41Å; G315-N318 PolarHBondContact O-N 3.02Å; Y316-N318 PolarHBondContact O-N 2.93Å; N318-G320 PolarHBondContact O-N 2.95Å; N318-G320 VanDerWaalsContact O-N 3.09Å; N318-F321 PolarHBondContact O-N 3.04Å
319	S	97.3	Very high	95.7	Very high	3 Å²	3	38.5 Å²	38.5	2%	0.021	20%	0.199	C	C	.	.	H	α-helix	trans	-61.3	-18.9	178	-65.4	0	0	0	0	113.5	N51 D79 Y316 V317	N51-S319 PolarHBondContact ND2-O 3.47Å; D79-S319 VanDerWaalsContact OD1-CA 3.3Å; D79-S319 WeakPolarHBondContact OD1-CA 3.32Å; D79-S319 WeakPolarHBondContact OD1-CB 3.16Å; D79-S319 PolarHBondContact OD1-OG 3.22Å; Y316-S319 WeakPolarHBondContact O-CB 3.45Å; Y316-S319 PolarHBondContact O-N 3.1Å; Y316-S319 VanDerWaalsContact O-N 3.16Å; V317-S319 PolarHBondContact O-N 2.71Å
320	G	96.5	Very high	95.5	Very high	13 Å²	13	38.8 Å²	38.8	13%	0.134	20%	0.204	C	C	.	.	H	α-helix	trans	-89.9	-17	174.3	0	0	0	0	0	114.3	V317 N318	V317-G320 PolarHBondContact O-N 3.09Å; N318-G320 PolarHBondContact O-N 2.95Å; N318-G320 VanDerWaalsContact O-N 3.09Å
321	F	97.3	Very high	95.3	Very high	76 Å²	76	35.9 Å²	35.9	33%	0.333	19%	0.19	S	C	.	.	H	α-helix	trans	-80.6	-30.7	-176.7	-64.1	-33.3	0	0	0	113.3	T281 V317 N318 L324 I325	T281-F321 HydrophobicContact CG2-CB 4.12Å; T281-F321 HydrophobicContact CG2-CD2 3.51Å; T281-F321 HydrophobicContact CG2-CE2 4.32Å; T281-F321 HydrophobicContact CG2-CG 4.21Å; V317-F321 HydrophobicContact CG1-CE1 3.86Å; V317-F321 HydrophobicContact CG1-CE2 3.93Å; V317-F321 HydrophobicContact CG1-CZ 3.44Å; V317-F321 VanDerWaalsContact CG1-CZ 3.44Å; N318-F321 PolarHBondContact O-N 3.04Å; F321-L324 WeakPolarHBondContact O-CB 3.44Å; F321-L324 PolarHBondContact O-N 3.47Å; F321-L324 VanDerWaalsContact O-N 3.12Å; F321-I325 HydrophobicContact CB-CD1 4.28Å; F321-I325 WeakPolarHBondContact O-CG1 3.05Å; F321-I325 PolarHBondContact O-N 3.45Å
322	N	94.4	Very high	95.1	Very high	1 Å²	1	34.9 Å²	34.9	1%	0.005	18%	0.184	C	C	.	.	H	α-helix	trans	-55.8	-51.8	-176.4	-68.4	-21.5	0	0	0	113	D79 L324 I325 Y326	D79-N322 PolarHBondContact OD2-ND2 3.48Å; N322-L324 VanDerWaalsContact C-N 3.29Å; N322-L324 PolarHBondContact O-N 3.45Å; N322-I325 PolarHBondContact O-N 3.32Å; N322-Y326 HydrophobicContact CB-CE2 3.96Å; N322-Y326 WeakPolarHBondContact O-CD2 3.18Å; N322-Y326 WeakPolarHBondContact O-CE2 3.31Å; N322-Y326 PolarHBondContact O-N 3.45Å
323	P	95.2	Very high	94.9	Very high	10 Å²	10	40.1 Å²	40.1	7%	0.065	20%	0.202	C	C	.	.	H	α-helix	trans	-53.3	-41.2	174.5	-27.9	36.7	0	0	0	114.2	G50 V54 Y326 C327	G50-P323 WeakPolarHBondContact O-CG 3.08Å; V54-P323 HydrophobicContact CG2-CB 4.15Å; V54-P323 HydrophobicContact CG2-CG 4.15Å; P323-Y326 PolarHBondContact O-N 3.12Å; P323-C327 PolarHBondContact O-N 3.1Å
324	L	95.5	Very high	94.7	Very high	121 Å²	121	41.6 Å²	41.6	63%	0.634	21%	0.211	S	C	*	.	H	α-helix	trans	-66.1	-38.8	178.4	-59.8	177.1	0	0	0	111.7	F321 N322 Y326 C327	F321-L324 WeakPolarHBondContact O-CB 3.44Å; F321-L324 PolarHBondContact O-N 3.47Å; F321-L324 VanDerWaalsContact O-N 3.12Å; N322-L324 VanDerWaalsContact C-N 3.29Å; N322-L324 PolarHBondContact O-N 3.45Å; L324-Y326 VanDerWaalsContact C-N 3.35Å; L324-C327 WeakPolarHBondContact O-CB 3.43Å; L324-C327 PolarHBondContact O-N 2.75Å
325	I	95.4	Very high	94.5	Very high	17 Å²	17	38.4 Å²	38.4	9%	0.087	20%	0.195	C	C	.	.	H	α-helix	trans	-67.7	-36.9	177.8	-63.5	161.1	0	0	0	110.6	T274 I277 I278 F321 N322 C327 R328	T274-I325 HydrophobicContact CG2-CG2 3.79Å; I277-I325 HydrophobicContact CB-CG2 4.3Å; I277-I325 HydrophobicContact CG2-CD1 4.01Å; I277-I325 HydrophobicContact CG2-CG1 4.08Å; I277-I325 HydrophobicContact CG2-CG2 3.96Å; I278-I325 HydrophobicContact CD1-CG2 4.23Å; I278-I325 HydrophobicContact CG1-CB 4.18Å; I278-I325 HydrophobicContact CG1-CD1 4.16Å; I278-I325 HydrophobicContact CG1-CG2 3.58Å; F321-I325 HydrophobicContact CB-CD1 4.28Å; F321-I325 WeakPolarHBondContact O-CG1 3.05Å; F321-I325 PolarHBondContact O-N 3.45Å; N322-I325 PolarHBondContact O-N 3.32Å; I325-C327 PolarHBondContact O-N 3.24Å; I325-R328 VanDerWaalsContact O-CB 3.24Å; I325-R328 WeakPolarHBondContact O-CB 3.47Å; I325-R328 VanDerWaalsContact O-CG 3.24Å; I325-R328 WeakPolarHBondContact O-CG 3.2Å; I325-R328 PolarHBondContact O-N 3.48Å; I325-R328 VanDerWaalsContact O-N 3.09Å
326	Y	93.8	Very high	94.4	Very high	6 Å²	6	39 Å²	39	2%	0.024	20%	0.198	C	C	.	.	H	α-helix	trans	-64.2	-24.4	178	-63	-49.4	0	0	0	113.9	V54 I72 I278 N322 P323 L324 R328 S329 F332	V54-Y326 HydrophobicContact CG1-CD2 4.28Å; V54-Y326 HydrophobicContact CG1-CE2 4.16Å; V54-Y326 HydrophobicContact CG2-CD2 3.6Å; V54-Y326 HydrophobicContact CG2-CE2 4.03Å; I72-Y326 HydrophobicContact CD1-CE1 3.78Å; I72-Y326 HydrophobicContact CG1-CE1 4.05Å; I72-Y326 HydrophobicContact CG2-CE1 3.88Å; I72-Y326 HydrophobicContact CG2-CE2 3.83Å; I72-Y326 VanDerWaalsContact CG2-CZ 3.43Å; I72-Y326 WeakPolarHBondContact CG2-OH 3.08Å; I278-Y326 HydrophobicContact CD1-CD1 3.98Å; I278-Y326 HydrophobicContact CD1-CE1 3.23Å; N322-Y326 HydrophobicContact CB-CE2 3.96Å; N322-Y326 WeakPolarHBondContact O-CD2 3.18Å; N322-Y326 WeakPolarHBondContact O-CE2 3.31Å; N322-Y326 PolarHBondContact O-N 3.45Å; P323-Y326 PolarHBondContact O-N 3.12Å; L324-Y326 VanDerWaalsContact C-N 3.35Å; Y326-R328 PolarHBondContact O-N 2.81Å; Y326-S329 WeakPolarHBondContact O-CB 3.21Å; Y326-S329 PolarHBondContact O-N 3.49Å; Y326-F332 WeakPolarHBondContact O-CB 3.3Å
327	C	93.3	Very high	94.2	Very high	56 Å²	56	43 Å²	43	38%	0.378	22%	0.216	S	C	.	.	T	Hydrogen-bonded Turn	trans	-57.6	-16.9	172	-68.5	0	0	0	0	113.7	P323 L324 I325 S329	P323-C327 PolarHBondContact O-N 3.1Å; L324-C327 WeakPolarHBondContact O-CB 3.43Å; L324-C327 PolarHBondContact O-N 2.75Å; I325-C327 PolarHBondContact O-N 3.24Å; C327-S329 VanDerWaalsContact C-N 3.29Å
328	R	91	Very high	94	Very high	129 Å²	129	44.9 Å²	44.9	49%	0.487	22%	0.222	S	C	.	.	T	Hydrogen-bonded Turn	trans	-69.7	-25.4	172	-62.8	175	56.9	74.4	6.7	113	T274 I325 Y326	T274-R328 HydrophobicContact CG2-CB 4.35Å; I325-R328 VanDerWaalsContact O-CB 3.24Å; I325-R328 WeakPolarHBondContact O-CB 3.47Å; I325-R328 VanDerWaalsContact O-CG 3.24Å; I325-R328 WeakPolarHBondContact O-CG 3.2Å; I325-R328 PolarHBondContact O-N 3.48Å; I325-R328 VanDerWaalsContact O-N 3.09Å; Y326-R328 PolarHBondContact O-N 2.81Å
329	S	89.3	Confident	93.8	Very high	30 Å²	30	46.7 Å²	46.7	21%	0.21	23%	0.232	C	C	.	.	S	Bend	trans	-79.3	123.1	174.3	176.2	0	0	0	0	109.8	Y326 C327 D331 F332 R333	Y326-S329 WeakPolarHBondContact O-CB 3.21Å; Y326-S329 PolarHBondContact O-N 3.49Å; C327-S329 VanDerWaalsContact C-N 3.29Å; S329-D331 PolarHBondContact O-N 3.29Å; S329-F332 PolarHBondContact O-N 3.16Å; S329-R333 WeakPolarHBondContact O-CB 3.21Å; S329-R333 PolarHBondContact O-N 3.4Å
330	P	90	Very high	93.7	Very high	62 Å²	62	49.8 Å²	49.8	40%	0.403	25%	0.248	S	C	.	.	H	α-helix	trans	-56.9	-36.2	177.5	-24.8	34.1	0	0	0	113	R333 I334	P330-R333 PolarHBondContact O-N 2.94Å; P330-I334 WeakPolarHBondContact O-CD1 3.16Å; P330-I334 VanDerWaalsContact O-CG1 3.26Å; P330-I334 WeakPolarHBondContact O-CG1 3.09Å; P330-I334 PolarHBondContact O-N 3.13Å
331	D	91.2	Very high	93.4	Very high	45 Å²	45	54.8 Å²	54.8	24%	0.241	28%	0.279	C	S	.	.	H	α-helix	trans	-69.9	-40.7	-176.5	-61	-44.7	0	0	0	111.1	R63 L64 K267 S329 A335	R63-D331 PolarHBondContact NH2-O 3.1Å; R63-D331 VanDerWaalsContact NH2-O 3.12Å; L64-D331 HydrophobicContact CD2-CB 3.71Å; K267-D331 IonicContact NZ-OD1 3.73Å; K267-D331 IonicContact NZ-OD2 2.73Å; K267-D331 PolarHBondContact NZ-OD2 3.23Å; S329-D331 PolarHBondContact O-N 3.29Å; D331-A335 WeakPolarHBondContact O-CB 3.35Å; D331-A335 PolarHBondContact O-N 3.27Å
332	F	93.4	Very high	92.8	Very high	6 Å²	6	57 Å²	57	3%	0.026	29%	0.294	C	S	.	.	H	α-helix	trans	-68.8	-43.2	171.9	-84.3	-82.3	0	0	0	112.2	V54 I58 L64 I72 Y326 S329 I334 A335 F336	V54-F332 HydrophobicContact CG1-CE1 4.37Å; I58-F332 HydrophobicContact CD1-CE1 4.04Å; I58-F332 HydrophobicContact CD1-CZ 3.92Å; I58-F332 HydrophobicContact CG1-CE1 3.83Å; I58-F332 HydrophobicContact CG1-CZ 3.91Å; L64-F332 HydrophobicContact CD1-CD1 4.31Å; L64-F332 HydrophobicContact CD1-CE1 4.36Å; L64-F332 HydrophobicContact CD2-CD2 4.35Å; L64-F332 HydrophobicContact CD2-CE2 4.35Å; I72-F332 HydrophobicContact CG2-CZ 4.45Å; Y326-F332 WeakPolarHBondContact O-CB 3.3Å; S329-F332 PolarHBondContact O-N 3.16Å; F332-I334 VanDerWaalsContact C-N 3.32Å; F332-I334 PolarHBondContact O-N 2.99Å; F332-A335 WeakPolarHBondContact O-CB 3.42Å; F332-A335 PolarHBondContact O-N 2.89Å; F332-A335 VanDerWaalsContact O-N 3.1Å; F332-F336 HydrophobicContact CB-CE2 4.23Å; F332-F336 HydrophobicContact CB-CZ 4.27Å; F332-F336 AromaticContact CD1-CE1 3.91Å; F332-F336 HydrophobicContact CD1-CE1 3.91Å; F332-F336 HydrophobicContact CD1-CE2 4.45Å; F332-F336 AromaticContact CD1-CZ 3.69Å; F332-F336 HydrophobicContact CD1-CZ 3.69Å; F332-F336 HydrophobicContact CG-CZ 4.42Å; F332-F336 VanDerWaalsContact O-CG 3.25Å; F332-F336 WeakPolarHBondContact O-CG 3.08Å; F332-F336 PolarHBondContact O-N 3.41Å
333	R	93.6	Very high	91.6	Very high	133 Å²	133	63.6 Å²	63.6	50%	0.502	32%	0.319	S	S	.	.	H	α-helix	trans	-58.8	-43.4	179.6	-174.2	174.2	65.2	-172.9	1.1	112.2	S329 P330 Q337	S329-R333 WeakPolarHBondContact O-CB 3.21Å; S329-R333 PolarHBondContact O-N 3.4Å; P330-R333 PolarHBondContact O-N 2.94Å; R333-Q337 WeakPolarHBondContact O-CB 3.4Å; R333-Q337 VanDerWaalsContact O-CG 3.26Å; R333-Q337 WeakPolarHBondContact O-CG 3.38Å; R333-Q337 PolarHBondContact O-N 3.32Å
334	I	92.9	Very high	89.7	Confident	56 Å²	56	74.3 Å²	74.3	29%	0.287	36%	0.358	S	S	.	.	H	α-helix	trans	-65.4	-43.6	176	-65.3	164	0	0	0	110.2	R63 P330 F332 F336 Q337 E338	R63-I334 VanDerWaalsContact NH2-CB 3.34Å; P330-I334 WeakPolarHBondContact O-CD1 3.16Å; P330-I334 VanDerWaalsContact O-CG1 3.26Å; P330-I334 WeakPolarHBondContact O-CG1 3.09Å; P330-I334 PolarHBondContact O-N 3.13Å; F332-I334 VanDerWaalsContact C-N 3.32Å; F332-I334 PolarHBondContact O-N 2.99Å; I334-F336 PolarHBondContact O-N 3.27Å; I334-Q337 PolarHBondContact O-N 3.47Å; I334-E338 WeakPolarHBondContact O-CB 3.49Å; I334-E338 PolarHBondContact O-N 2.86Å
335	A	94.1	Very high	87.3	Confident	0 Å²	0	73.6 Å²	73.6	0%	0	36%	0.363	C	S	.	.	H	α-helix	trans	-60	-44.7	177.8	0	0	0	0	0	112.2	A57 F61 L64 D331 F332 E338 L339	A57-A335 HydrophobicContact CB-CB 4.01Å; F61-A335 HydrophobicContact CD2-CB 3.43Å; F61-A335 VanDerWaalsContact CD2-CB 3.43Å; F61-A335 HydrophobicContact CE2-CB 3.47Å; F61-A335 VanDerWaalsContact CE2-CB 3.47Å; F61-A335 HydrophobicContact CG-CB 4.19Å; F61-A335 HydrophobicContact CZ-CB 4.23Å; L64-A335 HydrophobicContact CD1-CB 3.81Å; D331-A335 WeakPolarHBondContact O-CB 3.35Å; D331-A335 PolarHBondContact O-N 3.27Å; F332-A335 WeakPolarHBondContact O-CB 3.42Å; F332-A335 PolarHBondContact O-N 2.89Å; F332-A335 VanDerWaalsContact O-N 3.1Å; A335-E338 PolarHBondContact O-N 3.18Å; A335-L339 WeakPolarHBondContact O-CG 3.38Å; A335-L339 PolarHBondContact O-N 3.41Å
336	F	95.4	Very high	85.3	Confident	13 Å²	13	77.2 Å²	77.2	6%	0.057	39%	0.389	C	S	.	.	H	α-helix	trans	-64.8	-42.4	177.3	-63.7	-17.7	0	0	0	112.2	L53 V54 A57 F332 I334 E338 L339 L340	L53-F336 HydrophobicContact CD1-CD1 4.32Å; L53-F336 HydrophobicContact CD2-CB 4.05Å; L53-F336 HydrophobicContact CD2-CD1 3.63Å; L53-F336 HydrophobicContact CD2-CD2 4.21Å; L53-F336 HydrophobicContact CD2-CE1 4.05Å; L53-F336 HydrophobicContact CD2-CG 3.71Å; L53-F336 HydrophobicContact CG-CD1 3.55Å; L53-F336 HydrophobicContact CG-CE1 3.8Å; L53-F336 HydrophobicContact CG-CG 4.17Å; V54-F336 HydrophobicContact CG2-CE1 4.49Å; V54-F336 HydrophobicContact CG2-CZ 3.95Å; A57-F336 HydrophobicContact CB-CD1 4.06Å; A57-F336 HydrophobicContact CB-CE1 3.78Å; F332-F336 HydrophobicContact CB-CE2 4.23Å; F332-F336 HydrophobicContact CB-CZ 4.27Å; F332-F336 AromaticContact CD1-CE1 3.91Å; F332-F336 HydrophobicContact CD1-CE1 3.91Å; F332-F336 HydrophobicContact CD1-CE2 4.45Å; F332-F336 AromaticContact CD1-CZ 3.69Å; F332-F336 HydrophobicContact CD1-CZ 3.69Å; F332-F336 HydrophobicContact CG-CZ 4.42Å; F332-F336 VanDerWaalsContact O-CG 3.25Å; F332-F336 WeakPolarHBondContact O-CG 3.08Å; F332-F336 PolarHBondContact O-N 3.41Å; I334-F336 PolarHBondContact O-N 3.27Å; F336-E338 PolarHBondContact O-N 3.18Å; F336-L339 PolarHBondContact O-N 3.23Å; F336-L340 WeakPolarHBondContact O-CB 3.38Å; F336-L340 VanDerWaalsContact O-CG 3.25Å; F336-L340 WeakPolarHBondContact O-CG 3.49Å; F336-L340 PolarHBondContact O-N 3Å
337	Q	93.6	Very high	83.1	Confident	84 Å²	84	84.6 Å²	84.6	39%	0.393	43%	0.429	S	S	.	.	H	α-helix	trans	-61.1	-35.2	175.6	-75	173.7	-16	0	0	112.6	R333 I334 C341 L342 R343	R333-Q337 WeakPolarHBondContact O-CB 3.4Å; R333-Q337 VanDerWaalsContact O-CG 3.26Å; R333-Q337 WeakPolarHBondContact O-CG 3.38Å; R333-Q337 PolarHBondContact O-N 3.32Å; I334-Q337 PolarHBondContact O-N 3.47Å; Q337-C341 PolarHBondContact O-N 3.16Å; Q337-L342 PolarHBondContact O-N 3.17Å; Q337-R343 PolarHBondContact O-N 3.06Å
338	E	92.9	Very high	80.4	Confident	82 Å²	82	91.8 Å²	91.8	38%	0.383	45%	0.453	S	S	.	.	H	α-helix	trans	-74.9	-40.7	177.5	-170.8	171.1	150.9	0	0	112.2	F61 I334 A335 F336 C341 R343	F61-E338 VanDerWaalsContact CE1-CD 3.47Å; F61-E338 HydrophobicContact CE1-CG 4.35Å; F61-E338 WeakPolarHBondContact CE1-OE1 3.48Å; F61-E338 HydrophobicContact CZ-CB 3.91Å; F61-E338 HydrophobicContact CZ-CG 3.95Å; I334-E338 WeakPolarHBondContact O-CB 3.49Å; I334-E338 PolarHBondContact O-N 2.86Å; A335-E338 PolarHBondContact O-N 3.18Å; F336-E338 PolarHBondContact O-N 3.18Å; E338-C341 PolarHBondContact O-N 3.47Å; E338-R343 IonicContact OE2-NH1 3.72Å
339	L	94.1	Very high	78.1	Confident	38 Å²	38	90.2 Å²	90.2	20%	0.199	47%	0.468	C	S	.	.	H	α-helix	trans	-66.8	-36.6	175.6	-71.7	173.7	0	0	0	113.1	L53 T56 A57 K60 F61 A335 F336 C341	L53-L339 HydrophobicContact CD1-CB 3.84Å; L53-L339 HydrophobicContact CD1-CD1 3.78Å; L53-L339 HydrophobicContact CD1-CG 4.48Å; T56-L339 HydrophobicContact CG2-CD1 4.07Å; T56-L339 HydrophobicContact CG2-CD2 3.89Å; A57-L339 HydrophobicContact CB-CD1 3.83Å; K60-L339 HydrophobicContact CD-CD2 3.74Å; F61-L339 HydrophobicContact CE2-CD1 4.29Å; F61-L339 HydrophobicContact CE2-CD2 4.33Å; F61-L339 HydrophobicContact CE2-CG 3.99Å; A335-L339 WeakPolarHBondContact O-CG 3.38Å; A335-L339 PolarHBondContact O-N 3.41Å; F336-L339 PolarHBondContact O-N 3.23Å; L339-C341 PolarHBondContact O-N 3.22Å
340	L	94.1	Very high	75.8	Confident	68 Å²	68	100 Å²	100	36%	0.356	50%	0.502	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.1	7.7	179.1	-60.4	177.1	0	0	0	113	F49 L53 F336 L342	F49-L340 HydrophobicContact CE2-CD2 4.33Å; F49-L340 HydrophobicContact CZ-CD2 3.65Å; L53-L340 HydrophobicContact CD1-CD2 4.08Å; L53-L340 HydrophobicContact CD1-CG 4.29Å; L53-L340 HydrophobicContact CD2-CD1 4.23Å; L53-L340 HydrophobicContact CD2-CG 4.5Å; F336-L340 WeakPolarHBondContact O-CB 3.38Å; F336-L340 VanDerWaalsContact O-CG 3.25Å; F336-L340 WeakPolarHBondContact O-CG 3.49Å; F336-L340 PolarHBondContact O-N 3Å; L340-L342 HydrophobicContact CB-CD1 3.99Å; L340-L342 HydrophobicContact CB-CG 3.89Å; L340-L342 HydrophobicContact CD1-CD1 4.32Å; L340-L342 WeakPolarHBondContact O-CG 3.5Å; L340-L342 PolarHBondContact O-N 2.73Å; L340-L342 VanDerWaalsContact O-N 3.1Å
341	C	91.1	Very high	73.5	Confident	118 Å²	118	100.4 Å²	100.4	80%	0.797	52%	0.518	S	S	*	.	T	Hydrogen-bonded Turn	trans	56	25.9	-179	-58.3	0	0	0	0	114.1	Q337 E338 L339	Q337-C341 PolarHBondContact O-N 3.16Å; E338-C341 PolarHBondContact O-N 3.47Å; L339-C341 PolarHBondContact O-N 3.22Å
342	L	85.4	Confident	71.1	Confident	121 Å²	121	106.5 Å²	106.5	63%	0.634	55%	0.55	S	S	*	*			trans	-90	-4.3	-177	-63.7	179.2	0	0	0	113.4	Q337 L340 R344	Q337-L342 PolarHBondContact O-N 3.17Å; L340-L342 HydrophobicContact CB-CD1 3.99Å; L340-L342 HydrophobicContact CB-CG 3.89Å; L340-L342 HydrophobicContact CD1-CD1 4.32Å; L340-L342 WeakPolarHBondContact O-CG 3.5Å; L340-L342 PolarHBondContact O-N 2.73Å; L340-L342 VanDerWaalsContact O-N 3.1Å; L342-R344 VanDerWaalsContact C-N 3.34Å; L342-R344 PolarHBondContact O-N 3.05Å
343	R	67.9	Low	68.5	Low	141 Å²	141	109.8 Å²	109.8	53%	0.532	59%	0.586	S	S	.	*			trans	-72.4	87.3	-179.7	-164.9	173.1	-178.3	179.7	-3.6	110.3	Q337 E338 S345	Q337-R343 PolarHBondContact O-N 3.06Å; E338-R343 IonicContact OE2-NH1 3.72Å; R343-S345 PolarHBondContact O-N 3.14Å
344	R	55.7	Low	65.7	Low	235 Å²	235	114.7 Å²	114.7	89%	0.887	61%	0.606	S	S	*	*			trans	-53.3	127.2	163.2	-98.6	-178.4	178.4	-179.5	0.5	108.6	L342 S346	L342-R344 VanDerWaalsContact C-N 3.34Å; L342-R344 PolarHBondContact O-N 3.05Å; R344-S346 PolarHBondContact O-N 3.07Å
345	S	45.4	Very low	63.2	Low	106 Å²	106	117.7 Å²	117.7	74%	0.741	63%	0.632	S	S	*	*			trans	-46.1	100.3	-179	-42.2	0	0	0	0	111.6	R343 L347	R343-S345 PolarHBondContact O-N 3.14Å; S345-L347 PolarHBondContact O-N 3.24Å
346	S	52.2	Low	60.7	Low	92 Å²	92	122.8 Å²	122.8	64%	0.643	67%	0.667	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72.6	23.4	173.3	72.2	0	0	0	0	112.6	R344	R344-S346 PolarHBondContact O-N 3.07Å
347	L	47.4	Very low	58	Low	162 Å²	162	129.6 Å²	129.6	85%	0.848	70%	0.704	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.1	3.4	178	-114.9	96.8	0	0	0	113.8	S345	S345-L347 PolarHBondContact O-N 3.24Å
348	K	37.5	Very low	55.4	Low	206 Å²	206	129 Å²	129	90%	0.896	72%	0.72	S	S	*	*	S	Bend	trans	-96.4	11.3	-176.9	-120.4	176.5	-175.4	178.8	0	116
349	A	43.6	Very low	52.8	Low	97 Å²	97	132.3 Å²	132.3	80%	0.802	74%	0.741	S	S	*	*	S	Bend	trans	-115.8	12.1	-174.7	0	0	0	0	0	115.8
350	Y	39.3	Very low	50.3	Low	236 Å²	236	136.9 Å²	136.9	93%	0.925	77%	0.77	S	S	*	*	S	Bend	trans	-120.8	12.6	175.9	-144.3	-95.1	0	0	0	114.1
351	G	41.6	Very low	47.6	Very low	70 Å²	70	137.5 Å²	137.5	72%	0.722	79%	0.794	S	S	*	*	S	Bend	trans	-106.8	2.9	-170.7	0	0	0	0	0	117.4
352	N	41.2	Very low	45.1	Very low	173 Å²	173	140.4 Å²	140.4	93%	0.925	80%	0.795	S	S	*	*			trans	-128.6	28.3	-167.4	-114.9	39.7	0	0	0	115.6
353	G	39.4	Very low	42.8	Very low	75 Å²	75	143 Å²	143	77%	0.773	80%	0.804	S	S	*	*			trans	-97.6	-2.5	-179.2	0	0	0	0	0	116.9	S355	G353-S355 PolarHBondContact O-N 3.46Å
354	Y	35.2	Very low	41.3	Very low	236 Å²	236	142.2 Å²	142.2	93%	0.925	82%	0.82	S	S	*	*			trans	-91.6	96.6	178.7	-94	-89.8	0	0	0	111
355	S	41	Very low	40.2	Very low	119 Å²	119	133.8 Å²	133.8	83%	0.832	81%	0.807	S	S	*	*			trans	-159.3	122.3	157.4	-91.4	0	0	0	0	112.6	G353	G353-S355 PolarHBondContact O-N 3.46Å
356	S	39.8	Very low	39.6	Very low	106 Å²	106	139.1 Å²	139.1	74%	0.741	81%	0.812	S	S	*	*			trans	72	98.1	149.7	-145.4	0	0	0	0	119.3
357	N	40.3	Very low	38.8	Very low	157 Å²	157	142.6 Å²	142.6	84%	0.84	82%	0.818	S	S	*	*				-174	121.5	110.5	-95.6	-7.3	0	0	0	111.5
358	G	38.3	Very low	38	Very low	70 Å²	70	141.3 Å²	141.3	72%	0.722	82%	0.817	S	S	*	*			trans	-81.6	138	166.5	0	0	0	0	0	111.2
359	N	39.1	Very low	37.8	Very low	153 Å²	153	139.2 Å²	139.2	82%	0.818	81%	0.81	S	S	*	*			trans	-171	116.3	136.5	-103.4	-7.5	0	0	0	109.9
360	T	41.1	Very low	37.2	Very low	133 Å²	133	143.2 Å²	143.2	82%	0.816	81%	0.812	S	S	*	*			trans	35	115.5	139.1	55.5	0	0	0	0	119.4
361	G	37.1	Very low	36.8	Very low	82 Å²	82	140.9 Å²	140.9	85%	0.845	81%	0.81	S	S	*	*			trans	167.6	114.1	162.1	0	0	0	0	0	111.8
362	E	37.9	Very low	36.5	Very low	179 Å²	179	147.5 Å²	147.5	84%	0.836	82%	0.818	S	S	*	*			trans	-63.8	159.4	-174.2	-79.5	167.8	110	0	0	116.4
363	Q	37.4	Very low	36.1	Very low	175 Å²	175	147.4 Å²	147.4	82%	0.818	81%	0.812	S	S	*	*			trans	88.8	120.7	148.2	-81.5	170	18.4	0	0	121.5
364	S	37.2	Very low	35.8	Very low	125 Å²	125	152 Å²	152	87%	0.874	82%	0.819	S	S	*	*			trans	68.3	125	152.5	-124.2	0	0	0	0	116.1
365	G	33.4	Very low	35.7	Very low	58 Å²	58	150 Å²	150	60%	0.598	82%	0.815	S	S	*	*			cis	145.2	142.1	24	0	0	0	0	0	106.2
366	Y	32.3	Very low	35.2	Very low	218 Å²	218	152.3 Å²	152.3	86%	0.855	82%	0.818	S	S	*	*			trans	81	104.6	164.8	-60.6	-81.8	0	0	0	120.6
367	H	33.9	Very low	34.9	Very low	164 Å²	164	155.1 Å²	155.1	76%	0.759	82%	0.823	S	S	*	*			trans	25.8	113.2	132.2	-92.5	-85.4	0	0	0	118.9
368	V	32.5	Very low	34.5	Very low	136 Å²	136	154.1 Å²	154.1	82%	0.824	83%	0.827	S	S	*	*			trans	-127.4	94.5	154	179.5	0	0	0	0	107.8
369	E	32.6	Very low	34.3	Very low	162 Å²	162	158.5 Å²	158.5	76%	0.757	83%	0.829	S	S	*	*			trans	-122.9	144	160	-102.3	-178.8	138.1	0	0	107.2
370	Q	31.3	Very low	34.2	Very low	180 Å²	180	159.2 Å²	159.2	84%	0.841	83%	0.832	S	S	*	*			trans	78.4	68.2	178.4	-66.2	179	-38.9	0	0	118
371	E	31.3	Very low	33.9	Very low	188 Å²	188	160.2 Å²	160.2	88%	0.879	83%	0.832	S	S	*	*			trans	-123.4	72.5	152.1	-135.1	-173.8	-180	0	0	109.3
372	K	33.4	Very low	33.9	Very low	208 Å²	208	161.8 Å²	161.8	90%	0.904	83%	0.828	S	S	*	*	S	Bend	trans	-150	18.3	173.1	-124.8	177.6	-171.5	177.5	0	117
373	E	34.4	Very low	33.6	Very low	171 Å²	171	157.2 Å²	157.2	80%	0.799	83%	0.828	S	S	*	*	S	Bend	trans	-120.6	-2.9	-177.5	-125.3	174.3	162	0	0	116.2	K375	E373-K375 PolarHBondContact O-N 2.85Å
374	N	31.7	Very low	33.5	Very low	173 Å²	173	155.4 Å²	155.4	93%	0.925	83%	0.829	S	S	*	*			trans	-100.2	44	-174.1	-99.8	-9.6	0	0	0	115.5
375	K	33.5	Very low	33.3	Very low	193 Å²	193	158.2 Å²	158.2	84%	0.839	83%	0.829	S	S	*	*	S	Bend	trans	-142.7	38.9	-178.9	-124.2	-177.1	-163.5	175.9	0	116.7	E373	E373-K375 PolarHBondContact O-N 2.85Å
376	L	31.5	Very low	33.4	Very low	168 Å²	168	162.6 Å²	162.6	88%	0.88	84%	0.838	S	S	*	*			trans	-165.3	61	161.8	-146.1	72.4	0	0	0	115.7
377	L	32.4	Very low	33.3	Very low	165 Å²	165	161.5 Å²	161.5	86%	0.864	84%	0.838	S	S	*	*			trans	-142.6	91.7	165.1	-79	171.8	0	0	0	110.6
378	C	32.5	Very low	33.5	Very low	135 Å²	135	160.4 Å²	160.4	91%	0.912	84%	0.843	S	S	*	*			trans	-140.6	81.7	152.4	-73.9	0	0	0	0	106.4
379	E	34.9	Very low	33.5	Very low	162 Å²	162	156.8 Å²	156.8	76%	0.757	83%	0.833	S	S	*	*			trans	-107.8	113.2	155.5	-85.3	-176.4	122	0	0	106.7	L381	E379-L381 PolarHBondContact O-N 3.35Å
380	D	35.4	Very low	33.6	Very low	168 Å²	168	157.4 Å²	157.4	90%	0.898	84%	0.835	S	S	*	*			trans	-74	115.1	165.1	-74.4	-45.1	0	0	0	108.1
381	L	35.5	Very low	33.8	Very low	155 Å²	155	157 Å²	157	81%	0.812	83%	0.834	S	S	*	*	P	Polyproline II helix	trans	-82.5	138.6	167.6	-122.7	88.3	0	0	0	109.4	E379	E379-L381 PolarHBondContact O-N 3.35Å
382	P	36.3	Very low	33.8	Very low	115 Å²	115	151.3 Å²	151.3	75%	0.747	83%	0.825	S	S	*	*	P	Polyproline II helix	trans	-77.4	140	-178.7	29.7	-28.3	0	0	0	111.6
383	G	31.8	Very low	34	Very low	82 Å²	82	148.6 Å²	148.6	85%	0.845	83%	0.826	S	S	*	*	P	Polyproline II helix	trans	-58	140	-177.1	0	0	0	0	0	114.2
384	T	35.5	Very low	34.4	Very low	138 Å²	138	146.9 Å²	146.9	85%	0.847	83%	0.827	S	S	*	*			trans	-109.3	106.7	162.9	-39.4	0	0	0	0	106.1
385	E	33.1	Very low	34.8	Very low	184 Å²	184	144.1 Å²	144.1	86%	0.86	82%	0.818	S	S	*	*			trans	-73.3	125.6	162.3	-69.1	-179.3	128.1	0	0	107.3
386	D	34.7	Very low	35.2	Very low	150 Å²	150	140.9 Å²	140.9	80%	0.802	82%	0.82	S	S	*	*			trans	-167.5	114.6	139.2	-95.8	-28.3	0	0	0	111.1
387	F	31.9	Very low	35.4	Very low	194 Å²	194	140.4 Å²	140.4	85%	0.851	82%	0.818	S	S	*	*			trans	20.1	126.3	145.9	-83.9	-98.6	0	0	0	119.9
388	V	37.8	Very low	35.7	Very low	142 Å²	142	140.6 Å²	140.6	86%	0.861	82%	0.82	S	S	*	*				-176.5	126.8	114.1	156.7	0	0	0	0	108.2
389	G	31.3	Very low	36.1	Very low	59 Å²	59	141.6 Å²	141.6	61%	0.608	82%	0.815	S	S	*	*			trans	-86.7	159	-179.7	0	0	0	0	0	114.3
390	H	35.4	Very low	36.1	Very low	176 Å²	176	140.6 Å²	140.6	82%	0.815	82%	0.815	S	S	*	*				-168.9	127.3	128.6	-111.5	-56.3	0	0	0	112
391	Q	35.9	Very low	36.2	Very low	172 Å²	172	137.8 Å²	137.8	80%	0.804	81%	0.809	S	S	*	*			trans	-1.8	121.2	152.2	-78.3	155.8	-31	0	0	119.8
392	G	31.2	Very low	36.7	Very low	68 Å²	68	139.5 Å²	139.5	70%	0.701	81%	0.813	S	S	*	*				80.1	111.2	108	0	0	0	0	0	119.1
393	T	37.7	Very low	36.6	Very low	151 Å²	151	137.6 Å²	137.6	93%	0.926	81%	0.813	S	S	*	*				179	142.4	125.5	22.9	0	0	0	0	110.7
394	V	42.8	Very low	36.9	Very low	135 Å²	135	145.3 Å²	145.3	82%	0.818	82%	0.817	S	S	*	*			trans	-113.6	171.2	-174.5	-161.4	0	0	0	0	108
395	P	39.6	Very low	36.8	Very low	114 Å²	114	146.4 Å²	146.4	74%	0.74	82%	0.818	S	S	*	*				-118.8	-178.7	-87.9	39.1	-20.7	0	0	0	112.2
396	S	41.4	Very low	37	Very low	125 Å²	125	143.5 Å²	143.5	87%	0.874	82%	0.816	S	S	*	*			trans	-140	133.4	168.3	-50.3	0	0	0	0	111.1
397	D	35.7	Very low	37.1	Very low	158 Å²	158	141.2 Å²	141.2	85%	0.845	81%	0.812	S	S	*	*			trans	-56.8	144.2	-174.3	-64.7	-54.3	0	0	0	115.2
398	N	38.3	Very low	37.3	Very low	169 Å²	169	138 Å²	138	90%	0.904	81%	0.808	S	S	*	*			trans	-153.8	144.2	145.9	-109.9	-23.6	0	0	0	112.5
399	I	41.8	Very low	37.4	Very low	156 Å²	156	139.1 Å²	139.1	80%	0.8	81%	0.81	S	S	*	*			trans	-87.6	126.7	-158.3	-72.7	164.2	0	0	0	112.8
400	D	34	Very low	37.7	Very low	141 Å²	141	143.3 Å²	143.3	75%	0.754	82%	0.818	S	S	*	*				45.5	122.5	126.7	-133.5	1.4	0	0	0	122.5
401	S	39.3	Very low	37.8	Very low	110 Å²	110	139.9 Å²	139.9	77%	0.769	81%	0.814	S	S	*	*			trans	-172.1	79.7	140.2	59.2	0	0	0	0	111.2
402	Q	45.1	Very low	38	Very low	191 Å²	191	139.4 Å²	139.4	89%	0.893	82%	0.816	S	S	*	*			trans	176.2	101.1	144.1	-100	173.7	27.1	0	0	110.2	R404	Q402-R404 PolarHBondContact O-N 2.94Å
403	G	34.1	Very low	38.8	Very low	74 Å²	74	147.7 Å²	147.7	76%	0.763	84%	0.843	S	S	*	*			trans	-64.4	125.1	178	0	0	0	0	0	113.4
404	R	38.8	Very low	38.8	Very low	245 Å²	245	147.5 Å²	147.5	93%	0.925	84%	0.839	S	S	*	*			trans	-162.6	107.1	138	-115.6	177.6	-81.5	-173.2	-3.3	110.7	Q402	Q402-R404 PolarHBondContact O-N 2.94Å
405	N	32.6	Very low	38.6	Very low	161 Å²	161	148.2 Å²	148.2	86%	0.861	84%	0.84	S	S	*	*			trans	-73.5	138.1	166	-107.1	-19.1	0	0	0	110.1
406	C	36.6	Very low	38.5	Very low	122 Å²	122	150.1 Å²	150.1	82%	0.824	85%	0.845	S	S	*	*			trans	-167.6	90.6	134.9	-105.7	0	0	0	0	110.4
407	S	38.7	Very low	38.4	Very low	102 Å²	102	151.5 Å²	151.5	71%	0.713	84%	0.843	S	S	*	*			trans	34.3	114.9	133.4	55.7	0	0	0	0	120
408	T	36.2	Very low	38.5	Very low	126 Å²	126	151.1 Å²	151.1	77%	0.773	84%	0.843	S	S	*	*			trans	-32.7	141	146.7	43.4	0	0	0	0	115.8
409	N	39.9	Very low	38.6	Very low	167 Å²	167	149.9 Å²	149.9	89%	0.893	84%	0.839	S	S	*	*			trans	-150	118	133.9	-106.4	-9.6	0	0	0	109.7
410	D	36	Very low	38.3	Very low	147 Å²	147	149.5 Å²	149.5	79%	0.786	84%	0.842	S	S	*	*			trans	-54.4	151.7	159.6	-72.4	-53	0	0	0	111.1
411	S	37.6	Very low	38.7	Very low	103 Å²	103	150.2 Å²	150.2	72%	0.72	85%	0.849	S	S	*	*				155.8	123.3	124.7	-68.1	0	0	0	0	113.8
412	L	40.8	Very low	38.6	Very low	162 Å²	162	153.5 Å²	153.5	85%	0.848	86%	0.856	S	S	*	*			trans	66.2	97.1	138.8	-65.9	161.5	0	0	0	120.1
413	L	46.8	Very low	38	Very low	242 Å²	242	150.1 Å²	150.1	100%	1.267	85%	0.852	S	S	*	*				166.8	0	102.1	-104.9	162.4	0	0	0	111.7

Retrieved 413 of 413 residues in 101.7 ms (Link to these results)

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