A0A023IP86_HUMAN Loading...

Integrin a4-subunit

AlphaFold DB , UniProt , Accession A0A023IP86, Species HUMAN (Homo sapiens, Human), Gene ITGA4, Length 31 aa.

						>A0A023IP86_HUMAN|A0A023IP86|ITGA4
AGFFKRQYKSILQEENRRDSWSYINSKSNDD
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	A	52.5	Low	64	Low	164 Å²	164	133.5 Å²	133.5	100%	1.355	67%	0.673	S	S	*	*				0	129.5	0	0	0	0	0	0	109.4
2	G	60.5	Low	64	Low	48 Å²	48	130.2 Å²	130.2	50%	0.495	66%	0.657	S	S	.	*			trans	-168.1	28.2	-178.5	0	0	0	0	0	115.2	F4	G2-F4 VanDerWaalsContact C-N 3.34Å
3	F	65.1	Low	63.9	Low	153 Å²	153	132.5 Å²	132.5	67%	0.671	66%	0.664	S	S	*	*	H	α-helix	trans	-60.1	-46	175.7	-177.8	-102.5	0	0	0	110.9	K5 Q7	F3-K5 PolarHBondContact O-N 3.41Å; F3-Q7 WeakPolarHBondContact O-CG 3.45Å; F3-Q7 PolarHBondContact O-N 3.42Å; F3-Q7 HydrophobicContact CZ-CG 4.49Å
4	F	66.8	Low	63.5	Low	175 Å²	175	130.8 Å²	130.8	77%	0.768	65%	0.653	S	S	*	*	H	α-helix	trans	-64.1	-37.6	-179.1	-65.7	-79.5	0	0	0	114.1	G2 R6 Y8	G2-F4 VanDerWaalsContact C-N 3.34Å; F4-R6 PolarHBondContact O-N 3.01Å; F4-Y8 WeakPolarHBondContact O-CB 3.32Å; F4-Y8 PolarHBondContact O-N 3.5Å
5	K	66.3	Low	63.1	Low	181 Å²	181	130.9 Å²	130.9	79%	0.787	65%	0.651	S	S	*	*	H	α-helix	trans	-71.5	-32.1	-176.2	-90.1	-172.6	174.8	-169	0	114	F3	F3-K5 PolarHBondContact O-N 3.41Å
6	R	66.9	Low	62.8	Low	203 Å²	203	131.5 Å²	131.5	77%	0.766	66%	0.657	S	S	*	*	H	α-helix	trans	-77.5	-41	179.6	-167.1	175.7	-65.7	-109.3	1.1	111	F4	F4-R6 PolarHBondContact O-N 3.01Å
7	Q	64.9	Low	62.8	Low	82 Å²	82	137.2 Å²	137.2	38%	0.383	67%	0.669	S	S	.	*	H	α-helix	trans	-71.6	-30.6	178.3	-61.7	-56.3	-42.1	0	0	112.7	F3 K9 S10 I11	F3-Q7 WeakPolarHBondContact O-CG 3.45Å; F3-Q7 PolarHBondContact O-N 3.42Å; F3-Q7 HydrophobicContact CZ-CG 4.49Å; Q7-K9 VanDerWaalsContact C-N 3.3Å; Q7-K9 PolarHBondContact O-N 3.05Å; Q7-S10 WeakPolarHBondContact O-CB 3.49Å; Q7-S10 PolarHBondContact O-N 3.19Å; Q7-I11 PolarHBondContact O-N 2.85Å; Q7-I11 WeakPolarHBondContact O-CG1 3.24Å; Q7-I11 WeakPolarHBondContact O-CD1 3.49Å; Q7-I11 HydrophobicContact CB-CD1 4.11Å; Q7-I11 VanDerWaalsContact O-CG1 3.24Å
8	Y	64.6	Low	62.8	Low	155 Å²	155	134.3 Å²	134.3	61%	0.608	65%	0.65	S	S	*	*	H	α-helix	trans	-55.3	-42.3	-178.8	-176	-101.1	0	0	0	113.5	F4 L12	F4-Y8 WeakPolarHBondContact O-CB 3.32Å; F4-Y8 PolarHBondContact O-N 3.5Å; Y8-L12 HydrophobicContact CD1-CD1 3.85Å; Y8-L12 HydrophobicContact CE1-CD1 3.34Å; Y8-L12 HydrophobicContact CE2-CD1 4.48Å; Y8-L12 PolarHBondContact O-N 3.24Å
9	K	65	Low	62.7	Low	158 Å²	158	135.2 Å²	135.2	69%	0.687	66%	0.658	S	S	*	*	H	α-helix	trans	-70.9	-36	177.9	-65.7	-169.2	175.7	-165.6	0	112.5	Q7 Q13	Q7-K9 VanDerWaalsContact C-N 3.3Å; Q7-K9 PolarHBondContact O-N 3.05Å; K9-Q13 PolarHBondContact O-N 3.24Å
10	S	65	Low	62.5	Low	61 Å²	61	134 Å²	134	43%	0.427	66%	0.664	S	S	.	*	H	α-helix	trans	-68.3	-41	177.5	-58.2	0	0	0	0	111.6	Q7 Q13 E14	Q7-S10 WeakPolarHBondContact O-CB 3.49Å; Q7-S10 PolarHBondContact O-N 3.19Å; S10-Q13 PolarHBondContact O-N 2.63Å; S10-E14 WeakPolarHBondContact O-CB 3.36Å; S10-E14 PolarHBondContact O-N 3.02Å
11	I	66.6	Low	62.7	Low	89 Å²	89	135.9 Å²	135.9	46%	0.456	66%	0.664	S	S	.	*	H	α-helix	trans	-64	-43.7	177.2	-65.9	162.4	0	0	0	111	Q7 Q13 E14 E15	Q7-I11 PolarHBondContact O-N 2.85Å; Q7-I11 WeakPolarHBondContact O-CG1 3.24Å; Q7-I11 WeakPolarHBondContact O-CD1 3.49Å; Q7-I11 HydrophobicContact CB-CD1 4.11Å; Q7-I11 VanDerWaalsContact O-CG1 3.24Å; I11-Q13 VanDerWaalsContact C-N 3.34Å; I11-Q13 PolarHBondContact O-N 3.35Å; I11-E14 PolarHBondContact O-N 3.01Å; I11-E15 PolarHBondContact O-N 3.21Å
12	L	64.1	Low	63.3	Low	93 Å²	93	133 Å²	133	49%	0.487	63%	0.634	S	S	.	*	H	α-helix	trans	-60.7	-39.3	176.1	-95.3	160	0	0	0	113.3	Y8 E14	Y8-L12 HydrophobicContact CD1-CD1 3.85Å; Y8-L12 HydrophobicContact CE1-CD1 3.34Å; Y8-L12 HydrophobicContact CE2-CD1 4.48Å; Y8-L12 PolarHBondContact O-N 3.24Å; L12-E14 VanDerWaalsContact C-N 3.35Å
13	Q	62.4	Low	63.4	Low	160 Å²	160	139.5 Å²	139.5	75%	0.748	65%	0.645	S	S	*	*	H	α-helix	trans	-72.6	-32.5	177.6	-126.4	173	72.4	0	0	112	K9 S10 I11	K9-Q13 PolarHBondContact O-N 3.24Å; S10-Q13 PolarHBondContact O-N 2.63Å; I11-Q13 VanDerWaalsContact C-N 3.34Å; I11-Q13 PolarHBondContact O-N 3.35Å
14	E	59.1	Low	63.4	Low	109 Å²	109	139 Å²	139	51%	0.509	65%	0.647	S	S	.	*	H	α-helix	trans	-75.1	-31	179.9	-162.8	166.9	101.3	0	0	112.2	S10 I11 L12 N16 R17 R18	S10-E14 WeakPolarHBondContact O-CB 3.36Å; S10-E14 PolarHBondContact O-N 3.02Å; I11-E14 PolarHBondContact O-N 3.01Å; L12-E14 VanDerWaalsContact C-N 3.35Å; E14-N16 PolarHBondContact O-N 2.91Å; E14-N16 VanDerWaalsContact C-N 3.34Å; E14-R17 PolarHBondContact O-N 2.96Å; E14-R18 VanDerWaalsContact CD-NH2 3.28Å; E14-R18 VanDerWaalsContact O-CB 3.32Å; E14-R18 WeakPolarHBondContact O-CB 3.32Å; E14-R18 PolarHBondContact O-N 2.91Å; E14-R18 IonicContact OE1-CZ 3.26Å; E14-R18 VanDerWaalsContact OE1-CZ 3.26Å; E14-R18 IonicContact OE1-NE 3.97Å; E14-R18 IonicContact OE1-NH1 3.76Å; E14-R18 IonicContact OE1-NH2 2.63Å; E14-R18 PolarHBondContact OE1-NH2 3.46Å
15	E	56.7	Low	63.3	Low	132 Å²	132	136.1 Å²	136.1	62%	0.617	64%	0.64	S	S	*	*	H	α-helix	trans	-59.2	-39.5	171.8	-89.7	-142.4	96.4	0	0	113.1	I11 R17 R18	I11-E15 PolarHBondContact O-N 3.21Å; E15-R17 PolarHBondContact O-N 3.43Å; E15-R18 PolarHBondContact O-N 3.07Å
16	N	57.7	Low	63.2	Low	141 Å²	141	132.3 Å²	132.3	75%	0.754	64%	0.636	S	S	*	*	T	Hydrogen-bonded Turn	trans	-66.7	-20.6	179	-165.9	-103.3	0	0	0	113.2	E14	E14-N16 PolarHBondContact O-N 2.91Å; E14-N16 VanDerWaalsContact C-N 3.34Å
17	R	63.9	Low	63.1	Low	228 Å²	228	130.4 Å²	130.4	86%	0.86	63%	0.634	S	S	*	*	T	Hydrogen-bonded Turn	trans	-95.2	-8.7	170.1	-76.4	-176.8	170.3	171	-2.7	113.4	E14 E15	E14-R17 PolarHBondContact O-N 2.96Å; E15-R17 PolarHBondContact O-N 3.43Å
18	R	62.2	Low	62.9	Low	85 Å²	85	131.3 Å²	131.3	32%	0.321	65%	0.649	S	S	.	*			trans	-95	12.4	-172.9	-124.4	-175.9	-71.5	-153	-0.5	114	E14 E15 S20 W21	E14-R18 VanDerWaalsContact CD-NH2 3.28Å; E14-R18 VanDerWaalsContact O-CB 3.32Å; E14-R18 WeakPolarHBondContact O-CB 3.32Å; E14-R18 PolarHBondContact O-N 2.91Å; E14-R18 IonicContact OE1-CZ 3.26Å; E14-R18 VanDerWaalsContact OE1-CZ 3.26Å; E14-R18 IonicContact OE1-NE 3.97Å; E14-R18 IonicContact OE1-NH1 3.76Å; E14-R18 IonicContact OE1-NH2 2.63Å; E14-R18 PolarHBondContact OE1-NH2 3.46Å; E15-R18 PolarHBondContact O-N 3.07Å; R18-S20 PolarHBondContact O-N 3.2Å; R18-W21 HydrophobicContact CG-CE3 3.89Å; R18-W21 PolarHBondContact O-N 3.21Å
19	D	60.5	Low	62.8	Low	151 Å²	151	131.4 Å²	131.4	81%	0.807	66%	0.66	S	S	*	*	T	Hydrogen-bonded Turn	trans	-58.1	-8.6	176.8	-132.6	-94.8	0	0	0	113.6
20	S	58.4	Low	62.8	Low	111 Å²	111	131.4 Å²	131.4	78%	0.776	67%	0.668	S	S	*	*	T	Hydrogen-bonded Turn	trans	-101.4	17.6	173	-51.8	0	0	0	0	114.5	R18 S22	R18-S20 PolarHBondContact O-N 3.2Å; S20-S22 PolarHBondContact O-N 3.41Å
21	W	66.6	Low	62.3	Low	174 Å²	174	139.7 Å²	139.7	66%	0.659	71%	0.707	S	S	*	*			trans	-80.8	85.1	172.4	-156.1	-64.6	0	0	0	110.4	R18 Y23	R18-W21 HydrophobicContact CG-CE3 3.89Å; R18-W21 PolarHBondContact O-N 3.21Å; W21-Y23 VanDerWaalsContact C-N 3.27Å; W21-Y23 PolarHBondContact O-N 3.28Å
22	S	66.5	Low	62.1	Low	103 Å²	103	142.2 Å²	142.2	72%	0.72	72%	0.72	S	S	*	*			trans	-65.2	91.1	163.4	-52.4	0	0	0	0	107.9	S20 I24	S20-S22 PolarHBondContact O-N 3.41Å; S22-I24 VanDerWaalsContact C-N 3.34Å; S22-I24 PolarHBondContact O-N 3.1Å
23	Y	62.5	Low	62	Low	185 Å²	185	144.8 Å²	144.8	73%	0.725	73%	0.732	S	S	*	*			trans	-63.6	100.4	171.6	-175.6	-95.6	0	0	0	106.9	W21 N25	W21-Y23 VanDerWaalsContact C-N 3.27Å; W21-Y23 PolarHBondContact O-N 3.28Å; Y23-N25 HydrophobicContact CD1-CB 4.15Å; Y23-N25 HydrophobicContact CE1-CB 4.21Å; Y23-N25 PolarHBondContact O-N 2.92Å
24	I	65.8	Low	62	Low	142 Å²	142	143.9 Å²	143.9	73%	0.728	73%	0.731	S	S	*	*			trans	-69.4	91.9	175.5	-59	177.9	0	0	0	106	S22 S26	S22-I24 VanDerWaalsContact C-N 3.34Å; S22-I24 PolarHBondContact O-N 3.1Å; I24-S26 PolarHBondContact O-N 2.93Å
25	N	64.6	Low	62.2	Low	116 Å²	116	146 Å²	146	62%	0.62	74%	0.744	S	S	*	*			trans	-73.2	73.7	163.2	-176	42.6	0	0	0	107.6	Y23 K27	Y23-N25 HydrophobicContact CD1-CB 4.15Å; Y23-N25 HydrophobicContact CE1-CB 4.21Å; Y23-N25 PolarHBondContact O-N 2.92Å; N25-K27 PolarHBondContact O-N 2.88Å
26	S	63.9	Low	62.5	Low	101 Å²	101	146.9 Å²	146.9	71%	0.706	75%	0.752	S	S	*	*			trans	-76.1	60.9	166.2	57.8	0	0	0	0	108.6	I24 S28	I24-S26 PolarHBondContact O-N 2.93Å; S26-S28 PolarHBondContact O-N 2.83Å
27	K	64.1	Low	62.8	Low	162 Å²	162	147.3 Å²	147.3	70%	0.704	75%	0.752	S	S	*	*			trans	-87.7	95.5	160.8	-155.3	170.9	-172.7	178.4	0	105.1	N25 N29	N25-K27 PolarHBondContact O-N 2.88Å; K27-N29 PolarHBondContact O-N 2.86Å; K27-N29 VanDerWaalsContact O-N 3.1Å
28	S	60.8	Low	62.8	Low	101 Å²	101	141.5 Å²	141.5	71%	0.706	74%	0.744	S	S	*	*			trans	-41.5	116.9	168.8	-63.5	0	0	0	0	109	S26	S26-S28 PolarHBondContact O-N 2.83Å
29	N	63.1	Low	62.8	Low	157 Å²	157	145.8 Å²	145.8	84%	0.84	78%	0.777	S	S	*	*			trans	-94.9	91.5	155.4	-68.3	-61.3	0	0	0	104.7	K27 D31	K27-N29 PolarHBondContact O-N 2.86Å; K27-N29 VanDerWaalsContact O-N 3.1Å; N29-D31 PolarHBondContact O-N 3.07Å
30	D	64	Low	63	Low	159 Å²	159	145.4 Å²	145.4	85%	0.85	77%	0.774	S	S	*	*			trans	-65.4	102.1	151.8	-84.6	-66.1	0	0	0	106.5
31	D	55.7	Low	63.4	Low	234 Å²	234	148.5 Å²	148.5	100%	1.251	77%	0.774	S	S	*	*			trans	-155.3	0	148.1	-155.8	-99.8	0	0	0	109.5	N29	N29-D31 PolarHBondContact O-N 3.07Å

Retrieved 31 of 31 residues in 9.1 ms (Link to these results)

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