A0A023IPI3_HUMAN Loading...

Integrin a4 subunit

AlphaFold DB , UniProt , Accession A0A023IPI3, Species HUMAN (Homo sapiens, Human), Gene ITGA4, Length 43 aa.

						>A0A023IPI3_HUMAN|A0A023IPI3|ITGA4
DLIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQNQVKFGSYL
					

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	D	36.8	Very low	52.3	Low	220 Å²	220	124.5 Å²	124.5	100%	1.176	79%	0.79	S	S	*	*				0	128.7	0	-76.1	-99.4	0	0	111.8
2	L	43.6	Very low	52	Low	156 Å²	156	130.8 Å²	130.8	82%	0.817	79%	0.79	S	S	*	*			trans	-137.8	117.7	176.1	-173.6	71	0	0	108.8	V4	L2-V4 HydrophobicContact CG-CG2 4.41Å; L2-V4 HydrophobicContact CD2-CG2 4.29Å
3	I	60	Low	51.7	Low	146 Å²	146	140.9 Å²	140.9	75%	0.749	81%	0.805	S	S	*	*			trans	-95.1	113.5	175.7	-61	175.1	0	0	107.5	M5	I3-M5 HydrophobicContact CG2-CE 4.44Å; I3-M5 HydrophobicContact CG2-CG 4.08Å
4	V	55.3	Low	52	Low	124 Å²	124	138 Å²	138	75%	0.752	79%	0.792	S	S	*	*			trans	-93	101.6	174.6	178.1	0	0	0	107.9	L2	L2-V4 HydrophobicContact CG-CG2 4.41Å; L2-V4 HydrophobicContact CD2-CG2 4.29Å
5	M	63.8	Low	51.7	Low	165 Å²	165	134.1 Å²	134.1	81%	0.813	79%	0.794	S	S	*	*			trans	-93.4	109.8	167.6	-73.8	-176.9	-81.6	0	108.2	I3 A7	I3-M5 HydrophobicContact CG2-CE 4.44Å; I3-M5 HydrophobicContact CG2-CG 4.08Å; M5-A7 PolarHBondContact O-N 3.26Å
6	G	53.1	Low	52.2	Low	70 Å²	70	130.2 Å²	130.2	72%	0.722	78%	0.775	S	S	*	*			trans	-64.5	123.4	175	0	0	0	0	110.3	P8	G6-P8 WeakPolarHBondContact O-CD 3.36Å
7	A	56.3	Low	52.3	Low	80 Å²	80	131.2 Å²	131.2	66%	0.661	78%	0.775	S	S	*	*			trans	-96.1	95.7	169.3	0	0	0	0	108.9	M5 G9	M5-A7 PolarHBondContact O-N 3.26Å; A7-G9 PolarHBondContact O-N 2.8Å
8	P	53.4	Low	52.5	Low	141 Å²	141	134 Å²	134	92%	0.916	78%	0.776	S	S	*	*	T	Hydrogen-bonded Turn	trans	-79.8	54.8	176.4	35.9	-36.3	0	0	110.5	G6	G6-P8 WeakPolarHBondContact O-CD 3.36Å
9	G	48.7	Very low	52.4	Low	65 Å²	65	132 Å²	132	67%	0.67	77%	0.766	S	S	*	*	T	Hydrogen-bonded Turn	trans	-162.5	14.5	-175.7	0	0	0	0	115.2	A7	A7-G9 PolarHBondContact O-N 2.8Å
10	S	49.6	Very low	52.2	Low	104 Å²	104	135.3 Å²	135.3	73%	0.727	77%	0.767	S	S	*	*			trans	-98.4	17.7	178.2	-145.8	0	0	0	113.5	Y12	S10-Y12 PolarHBondContact O-N 3.2Å
11	S	55	Low	51.8	Low	99 Å²	99	132.7 Å²	132.7	69%	0.692	75%	0.751	S	S	*	*			trans	-61.9	106.4	143.3	-65.7	0	0	0	104.6
12	Y	48.4	Very low	52.6	Low	200 Å²	200	129.3 Å²	129.3	78%	0.784	73%	0.731	S	S	*	*				-140.4	134.5	55	-79.4	-100.2	0	0	109.8	S10 T14	S10-Y12 PolarHBondContact O-N 3.2Å; Y12-T14 PolarHBondContact O-N 2.99Å
13	W	47.7	Very low	53.1	Low	262 Å²	262	127.5 Å²	127.5	99%	0.992	73%	0.726	S	S	*	*			trans	-61.6	53.7	165.8	-178.3	59.9	0	0	111.7
14	T	56.8	Low	52.6	Low	100 Å²	100	124.4 Å²	124.4	61%	0.613	71%	0.714	S	S	*	*			trans	-122.7	73.1	174	-36.3	0	0	0	105	Y12 S16	Y12-T14 PolarHBondContact O-N 2.99Å; T14-S16 PolarHBondContact O-N 2.78Å
15	G	47.4	Very low	52.5	Low	80 Å²	80	125.7 Å²	125.7	83%	0.825	72%	0.717	S	S	*	*			trans	-59.5	74.8	150.1	0	0	0	0	107.3	L17	G15-L17 PolarHBondContact O-N 2.96Å
16	S	58.5	Low	51.8	Low	71 Å²	71	124.2 Å²	124.2	50%	0.497	71%	0.706	S	S	.	*			trans	-71.2	90.5	164.3	-168.4	0	0	0	103.4	T14 F18	T14-S16 PolarHBondContact O-N 2.78Å; S16-F18 WeakPolarHBondContact O-CD2 3.14Å; S16-F18 PolarHBondContact O-N 2.91Å
17	L	54.5	Low	51.9	Low	148 Å²	148	130.7 Å²	130.7	78%	0.775	71%	0.71	S	S	*	*			trans	-60.1	88.8	164.8	-166.9	73.5	0	0	104.4	G15 V19	G15-L17 PolarHBondContact O-N 2.96Å; L17-V19 PolarHBondContact O-N 3.15Å; L17-V19 VanDerWaalsContact CG-CG2 3.48Å; L17-V19 HydrophobicContact CD2-CG2 3.37Å; L17-V19 HydrophobicContact CB-CG2 4.21Å; L17-V19 HydrophobicContact CG-CG2 3.48Å
18	F	55.3	Low	51.6	Low	181 Å²	181	136 Å²	136	79%	0.794	72%	0.719	S	S	*	*			trans	-62.4	81.4	161.3	-77.2	-87.7	0	0	104.9	S16 Y20	S16-F18 WeakPolarHBondContact O-CD2 3.14Å; S16-F18 PolarHBondContact O-N 2.91Å; F18-Y20 PolarHBondContact O-N 3.1Å
19	V	50.6	Low	51.6	Low	96 Å²	96	132.1 Å²	132.1	58%	0.582	70%	0.699	S	S	*	*			trans	-70.8	71.2	162.8	-172	0	0	0	104.7	L17 N21	L17-V19 PolarHBondContact O-N 3.15Å; L17-V19 VanDerWaalsContact CG-CG2 3.48Å; L17-V19 HydrophobicContact CD2-CG2 3.37Å; L17-V19 HydrophobicContact CB-CG2 4.21Å; L17-V19 HydrophobicContact CG-CG2 3.48Å; V19-N21 HydrophobicContact CG1-CB 4.19Å; V19-N21 PolarHBondContact O-N 2.78Å
20	Y	50.2	Low	51.7	Low	198 Å²	198	136.6 Å²	136.6	78%	0.776	70%	0.7	S	S	*	*			trans	-66.9	87.9	160.3	-157.6	-93.4	0	0	104.7	F18 I22	F18-Y20 PolarHBondContact O-N 3.1Å; Y20-I22 VanDerWaalsContact C-N 3.29Å; Y20-I22 HydrophobicContact CD1-CG1 3.8Å; Y20-I22 HydrophobicContact CE1-CG1 4.36Å; Y20-I22 PolarHBondContact O-N 2.71Å
21	N	42.4	Very low	51.9	Low	81 Å²	81	139.2 Å²	139.2	43%	0.433	71%	0.705	S	S	.	*			trans	-74.1	90.9	-178.4	-151.8	-0.5	0	0	107	V19 T23 T24	V19-N21 HydrophobicContact CG1-CB 4.19Å; V19-N21 PolarHBondContact O-N 2.78Å; N21-T23 PolarHBondContact O-N 2.75Å; N21-T23 PolarHBondContact OD1-OG1 2.89Å; N21-T24 PolarHBondContact O-N 2.7Å; N21-T24 VanDerWaalsContact O-N 3.1Å; N21-T24 PolarHBondContact O-OG1 2.85Å
22	I	54.2	Low	51.7	Low	149 Å²	149	141.1 Å²	141.1	76%	0.764	71%	0.707	S	S	*	*	T	Hydrogen-bonded Turn	trans	-59.9	-5.4	172.5	-62.2	179	0	0	111.2	Y20	Y20-I22 VanDerWaalsContact C-N 3.29Å; Y20-I22 HydrophobicContact CD1-CG1 3.8Å; Y20-I22 HydrophobicContact CE1-CG1 4.36Å; Y20-I22 PolarHBondContact O-N 2.71Å
23	T	52.9	Low	52.1	Low	117 Å²	117	140.5 Å²	140.5	72%	0.718	71%	0.709	S	S	*	*	T	Hydrogen-bonded Turn	trans	-92.9	-7.7	176.9	-10.2	0	0	0	114.7	N21 N25	N21-T23 PolarHBondContact O-N 2.75Å; N21-T23 PolarHBondContact OD1-OG1 2.89Å; T23-N25 PolarHBondContact O-N 3.35Å
24	T	51.1	Low	52.6	Low	81 Å²	81	136.7 Å²	136.7	50%	0.497	70%	0.702	S	S	.	*			trans	-93.3	59.6	169	50	0	0	0	110.4	N21 K26	N21-T24 PolarHBondContact O-N 2.7Å; N21-T24 VanDerWaalsContact O-N 3.1Å; N21-T24 PolarHBondContact O-OG1 2.85Å; T24-K26 PolarHBondContact O-N 2.88Å
25	N	52.4	Low	52.4	Low	152 Å²	152	138.4 Å²	138.4	81%	0.813	71%	0.707	S	S	*	*	T	Hydrogen-bonded Turn	trans	-66.9	36.2	153.8	-159.7	14.7	0	0	111	T23	T23-N25 PolarHBondContact O-N 3.35Å
26	K	49.3	Very low	52.7	Low	133 Å²	133	141.5 Å²	141.5	58%	0.578	70%	0.7	S	S	*	*	T	Hydrogen-bonded Turn	trans	-122	17.3	-176.1	-102.7	-154.1	-179.9	-172.6	112.3	T24 K28 F30	T24-K26 PolarHBondContact O-N 2.88Å; K26-K28 PolarHBondContact O-N 3.28Å; K26-F30 HydrophobicContact CD-CE2 4.23Å
27	Y	54.6	Low	52.5	Low	206 Å²	206	144.9 Å²	144.9	81%	0.808	72%	0.718	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.3	2	164.9	-114	-83.6	0	0	113.7
28	K	50.8	Low	52.5	Low	192 Å²	192	146.7 Å²	146.7	84%	0.835	72%	0.719	S	S	*	*	T	Hydrogen-bonded Turn	trans	-109.2	-7.9	-179.1	-79.5	-164.1	164.4	-159.7	116.3	K26	K26-K28 PolarHBondContact O-N 3.28Å
29	A	52.7	Low	52.5	Low	60 Å²	60	148.2 Å²	148.2	50%	0.496	73%	0.726	S	S	.	*	T	Hydrogen-bonded Turn	trans	-111.2	-11	-173.5	0	0	0	0	115.1
30	F	51.9	Low	52.2	Low	159 Å²	159	147 Å²	147	70%	0.697	73%	0.733	S	S	*	*	S	Bend	trans	-112.2	12.9	-177.6	-78.6	-77.9	0	0	114.6	K26	K26-F30 HydrophobicContact CD-CE2 4.23Å
31	L	52.2	Low	52	Low	158 Å²	158	142.9 Å²	142.9	83%	0.827	73%	0.733	S	S	*	*	S	Bend	trans	-115.5	-8	172.1	-127.2	102.7	0	0	114.8
32	D	52	Low	52.4	Low	140 Å²	140	149.9 Å²	149.9	75%	0.749	76%	0.755	S	S	*	*	S	Bend	trans	-130	17.8	-168.1	-163.8	-114.6	0	0	114.6
33	K	56.4	Low	52.1	Low	187 Å²	187	154.8 Å²	154.8	81%	0.813	78%	0.781	S	S	*	*	S	Bend	trans	-150.3	8.6	-178.1	-122.6	175	-169.3	178.2	119.7
34	Q	58.5	Low	52	Low	181 Å²	181	156.7 Å²	156.7	85%	0.846	78%	0.784	S	S	*	*	S	Bend	trans	-144.7	106.8	173	-69.4	-173.8	-28.7	0	111.9
35	N	51.9	Low	52.1	Low	137 Å²	137	160.6 Å²	160.6	73%	0.733	80%	0.799	S	S	*	*			trans	111.4	71.1	145.9	-141.4	61	0	0	117.4
36	Q	54.1	Low	52	Low	145 Å²	145	161.1 Å²	161.1	68%	0.678	80%	0.799	S	S	*	*				54.2	103.7	118.6	-64.7	-179.6	-4.9	0	116.5	K38	Q36-K38 PolarHBondContact O-N 2.72Å
37	V	53.7	Low	52.2	Low	142 Å²	142	162.8 Å²	162.8	86%	0.861	81%	0.812	S	S	*	*			trans	-19.2	103.2	140	-83.7	0	0	0	113.2
38	K	55.5	Low	52	Low	185 Å²	185	160.1 Å²	160.1	80%	0.804	81%	0.812	S	S	*	*			trans	-138.4	109	151.9	-78.6	-165.1	176.5	179.5	109.1	Q36	Q36-K38 PolarHBondContact O-N 2.72Å
39	F	55.7	Low	52.1	Low	214 Å²	214	157.9 Å²	157.9	94%	0.939	81%	0.81	S	S	*	*			trans	-38	143.6	162.2	-75.3	-106.6	0	0	112.4
40	G	43.8	Very low	52.1	Low	71 Å²	71	164.9 Å²	164.9	73%	0.732	83%	0.833	S	S	*	*			trans	160.3	84.9	161.5	0	0	0	0	116
41	S	45.5	Very low	52.1	Low	110 Å²	110	165.4 Å²	165.4	77%	0.769	84%	0.843	S	S	*	*			trans	46.6	117.3	144	-58.4	0	0	0	121.6
42	Y	50.1	Low	52.1	Low	228 Å²	228	166 Å²	166	89%	0.894	85%	0.845	S	S	*	*				7	122.7	127	-60.3	-86.8	0	0	117
43	L	47.9	Very low	52.1	Low	252 Å²	252	168.4 Å²	168.4	100%	1.319	85%	0.853	S	S	*	*			trans	-146.6	0	135.6	-91.1	170.3	0	0	108.3

Retrieved 43 of 43 residues in 29.5 ms (Link to these results)

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