A0A023IQJ3_HUMAN Loading...

Integrin a4 subunit

AlphaFold DB , UniProt , Accession A0A023IQJ3, Species HUMAN (Homo sapiens, Human), Gene ITGA4, Length 28 aa.

						>A0A023IQJ3_HUMAN|A0A023IQJ3|ITGA4
SLFVYNITTNKYKAFLDKQNQVKFGSYL
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	S	72.6	Confident	73.7	Confident	130 Å²	130	114.8 Å²	114.8	91%	0.909	60%	0.597	S	S	*	*				0	121.4	0	-61.8	0	0	0	111.4	F3 V4	S1-F3 PolarHBondContact O-N 3.37Å; S1-V4 PolarHBondContact O-N 2.92Å
2	L	76.4	Confident	73.9	Confident	137 Å²	137	117.7 Å²	117.7	72%	0.717	60%	0.596	S	S	*	*	H	α-helix	trans	-56.3	-30.2	178.4	-173.9	62.5	0	0	112.5	V4 Y5 N6	L2-V4 PolarHBondContact O-N 3.23Å; L2-Y5 PolarHBondContact O-N 2.81Å; L2-N6 PolarHBondContact O-N 3.29Å; L2-N6 WeakPolarHBondContact O-CB 3.48Å
3	F	70.1	Confident	74.1	Confident	169 Å²	169	119.5 Å²	119.5	74%	0.741	60%	0.597	S	S	*	*	H	α-helix	trans	-55.6	-43.5	172.7	-72.5	-84.2	0	0	113.7	S1 N6 I7	S1-F3 PolarHBondContact O-N 3.37Å; F3-N6 PolarHBondContact O-N 2.86Å; F3-I7 WeakPolarHBondContact O-CB 3.18Å; F3-I7 VanDerWaalsContact O-CD1 3.32Å; F3-I7 WeakPolarHBondContact O-CD1 3.25Å; F3-I7 WeakPolarHBondContact O-CG1 3.39Å; F3-I7 PolarHBondContact O-N 3.26Å
4	V	71.1	Confident	74.2	Confident	91 Å²	91	115 Å²	115	55%	0.552	59%	0.588	S	S	*	*	H	α-helix	trans	-71.7	-40.1	-179.1	-179.5	0	0	0	110.6	S1 L2 N6 I7 T8	S1-V4 PolarHBondContact O-N 2.92Å; L2-V4 PolarHBondContact O-N 3.23Å; V4-N6 VanDerWaalsContact C-N 3.34Å; V4-N6 PolarHBondContact O-N 2.84Å; V4-I7 PolarHBondContact O-N 2.98Å; V4-T8 VanDerWaalsContact O-CB 3.31Å; V4-T8 WeakPolarHBondContact O-CB 3.18Å; V4-T8 PolarHBondContact O-N 3.4Å; V4-T8 PolarHBondContact O-OG1 2.98Å
5	Y	72.8	Confident	74.3	Confident	164 Å²	164	115.5 Å²	115.5	64%	0.643	58%	0.584	S	S	*	*	H	α-helix	trans	-61.6	-43.8	174.8	-174.2	-101.2	0	0	111.1	L2 T8 T9	L2-Y5 PolarHBondContact O-N 2.81Å; Y5-T8 PolarHBondContact O-N 2.73Å; Y5-T9 PolarHBondContact O-N 3.45Å; Y5-T9 WeakPolarHBondContact O-CB 3.22Å
6	N	69.9	Low	74.5	Confident	98 Å²	98	113.6 Å²	113.6	52%	0.524	58%	0.576	S	S	.	*	H	α-helix	trans	-68.4	-37.9	-179.4	-141.6	74.7	0	0	112.6	L2 F3 V4 N10	L2-N6 PolarHBondContact O-N 3.29Å; L2-N6 WeakPolarHBondContact O-CB 3.48Å; F3-N6 PolarHBondContact O-N 2.86Å; V4-N6 VanDerWaalsContact C-N 3.34Å; V4-N6 PolarHBondContact O-N 2.84Å; N6-N10 WeakPolarHBondContact O-CB 3.41Å; N6-N10 PolarHBondContact O-N 3Å
7	I	76.9	Confident	74.4	Confident	95 Å²	95	112.3 Å²	112.3	49%	0.487	57%	0.571	S	S	.	*	H	α-helix	trans	-68.9	-44.8	176	-67.7	162.3	0	0	110.9	F3 V4 K11	F3-I7 WeakPolarHBondContact O-CB 3.18Å; F3-I7 VanDerWaalsContact O-CD1 3.32Å; F3-I7 WeakPolarHBondContact O-CD1 3.25Å; F3-I7 WeakPolarHBondContact O-CG1 3.39Å; F3-I7 PolarHBondContact O-N 3.26Å; V4-I7 PolarHBondContact O-N 2.98Å; I7-K11 WeakPolarHBondContact O-CB 2.88Å; I7-K11 PolarHBondContact O-N 2.96Å
8	T	74.8	Confident	74.2	Confident	84 Å²	84	114.4 Å²	114.4	52%	0.515	58%	0.575	S	S	.	*	H	α-helix	trans	-68.6	-40.8	180	-59.8	0	0	0	111.2	V4 Y5 K11 Y12	V4-T8 VanDerWaalsContact O-CB 3.31Å; V4-T8 WeakPolarHBondContact O-CB 3.18Å; V4-T8 PolarHBondContact O-N 3.4Å; V4-T8 PolarHBondContact O-OG1 2.98Å; Y5-T8 PolarHBondContact O-N 2.73Å; T8-K11 PolarHBondContact O-N 3.41Å; T8-Y12 VanDerWaalsContact O-CB 3.27Å; T8-Y12 WeakPolarHBondContact O-CB 3.31Å; T8-Y12 PolarHBondContact O-N 2.95Å
9	T	76.2	Confident	73.9	Confident	48 Å²	48	114.4 Å²	114.4	29%	0.294	57%	0.573	S	S	.	*	H	α-helix	trans	-69.2	-39.1	177.5	-138.6	0	0	0	111.6	Y5 Y12 K13	Y5-T9 PolarHBondContact O-N 3.45Å; Y5-T9 WeakPolarHBondContact O-CB 3.22Å; T9-Y12 PolarHBondContact O-N 2.88Å; T9-K13 WeakPolarHBondContact O-CB 3.32Å; T9-K13 VanDerWaalsContact O-CG 3.27Å; T9-K13 WeakPolarHBondContact O-CG 3.3Å; T9-K13 PolarHBondContact O-N 3.34Å
10	N	74.4	Confident	73.4	Confident	108 Å²	108	111.6 Å²	111.6	58%	0.578	56%	0.56	S	S	*	*	H	α-helix	trans	-65.9	-43.1	175.7	-172.2	-69.8	0	0	111.2	N6 K13 A14	N6-N10 WeakPolarHBondContact O-CB 3.41Å; N6-N10 PolarHBondContact O-N 3Å; N10-K13 PolarHBondContact O-N 3.37Å; N10-A14 WeakPolarHBondContact O-CB 3.45Å; N10-A14 PolarHBondContact O-N 3.3Å
11	K	75.3	Confident	72.9	Confident	139 Å²	139	112.2 Å²	112.2	60%	0.604	56%	0.561	S	S	*	*	H	α-helix	trans	-63.6	-41.7	173.8	-82.9	-163	-76.3	-176.3	112.9	I7 T8 A14 F15	I7-K11 WeakPolarHBondContact O-CB 2.88Å; I7-K11 PolarHBondContact O-N 2.96Å; T8-K11 PolarHBondContact O-N 3.41Å; K11-A14 PolarHBondContact O-N 2.86Å; K11-F15 PolarHBondContact O-N 3.48Å; K11-F15 WeakPolarHBondContact O-CB 3.27Å
12	Y	76	Confident	72.3	Confident	149 Å²	149	111.8 Å²	111.8	58%	0.584	55%	0.553	S	S	*	*	H	α-helix	trans	-65.5	-43.8	177.9	-174.6	-100.1	0	0	111.4	T8 T9 F15 L16	T8-Y12 VanDerWaalsContact O-CB 3.27Å; T8-Y12 WeakPolarHBondContact O-CB 3.31Å; T8-Y12 PolarHBondContact O-N 2.95Å; T9-Y12 PolarHBondContact O-N 2.88Å; Y12-F15 PolarHBondContact O-N 3.43Å; Y12-L16 WeakPolarHBondContact O-CB 3.36Å; Y12-L16 PolarHBondContact O-N 2.88Å; Y12-L16 VanDerWaalsContact O-CB 3.25Å
13	K	76.3	Confident	71.5	Confident	142 Å²	142	112.4 Å²	112.4	62%	0.617	55%	0.55	S	S	*	.	H	α-helix	trans	-63.9	-41.5	174.8	-71.4	-172.6	73.4	163.6	112.2	T9 N10 L16 D17	T9-K13 WeakPolarHBondContact O-CB 3.32Å; T9-K13 VanDerWaalsContact O-CG 3.27Å; T9-K13 WeakPolarHBondContact O-CG 3.3Å; T9-K13 PolarHBondContact O-N 3.34Å; N10-K13 PolarHBondContact O-N 3.37Å; K13-L16 PolarHBondContact O-N 3.33Å; K13-D17 WeakPolarHBondContact O-CB 3.27Å; K13-D17 PolarHBondContact O-N 3.45Å
14	A	75.6	Confident	71	Confident	56 Å²	56	110.8 Å²	110.8	46%	0.463	54%	0.542	S	S	.	.	H	α-helix	trans	-66.5	-36.9	176.6	0	0	0	0	112.6	N10 K11 K18	N10-A14 WeakPolarHBondContact O-CB 3.45Å; N10-A14 PolarHBondContact O-N 3.3Å; K11-A14 PolarHBondContact O-N 2.86Å; A14-K18 VanDerWaalsContact O-CB 3.3Å; A14-K18 WeakPolarHBondContact O-CB 3.18Å; A14-K18 PolarHBondContact O-N 3Å
15	F	76.9	Confident	70.4	Confident	122 Å²	122	109.9 Å²	109.9	54%	0.535	55%	0.552	S	S	.	*	H	α-helix	trans	-69.3	-44.2	175.2	-176.6	-99	0	0	111.8	K11 Y12 K18 Q19	K11-F15 PolarHBondContact O-N 3.48Å; K11-F15 WeakPolarHBondContact O-CB 3.27Å; Y12-F15 PolarHBondContact O-N 3.43Å; F15-K18 PolarHBondContact O-N 2.91Å; F15-Q19 HydrophobicContact CD1-CG 4.5Å; F15-Q19 HydrophobicContact CE1-CG 4.21Å; F15-Q19 VanDerWaalsContact CE1-NE2 3.27Å; F15-Q19 HydrophobicContact CZ-CG 4.36Å; F15-Q19 VanDerWaalsContact CZ-NE2 3.26Å; F15-Q19 WeakPolarHBondContact O-CG 3.32Å; F15-Q19 PolarHBondContact O-N 3.42Å
16	L	77.2	Confident	69.9	Low	85 Å²	85	107.1 Å²	107.1	45%	0.445	56%	0.557	S	S	.	*	H	α-helix	trans	-63.5	-44.1	176	-172.9	70.3	0	0	111.1	Y12 K13 Q19 N20	Y12-L16 WeakPolarHBondContact O-CB 3.36Å; Y12-L16 PolarHBondContact O-N 2.88Å; Y12-L16 VanDerWaalsContact O-CB 3.25Å; K13-L16 PolarHBondContact O-N 3.33Å; L16-Q19 PolarHBondContact O-N 3.46Å; L16-N20 WeakPolarHBondContact O-CB 3.39Å; L16-N20 PolarHBondContact O-N 2.93Å
17	D	72.3	Confident	69.6	Low	92 Å²	92	112.1 Å²	112.1	49%	0.492	57%	0.569	S	S	.	*	H	α-helix	trans	-60.4	-46.4	175.8	-171.7	-102	0	0	111.3	K13 Q19 N20 Q21	K13-D17 WeakPolarHBondContact O-CB 3.27Å; K13-D17 PolarHBondContact O-N 3.45Å; D17-Q19 VanDerWaalsContact C-N 3.31Å; D17-Q19 PolarHBondContact O-N 3.49Å; D17-N20 CarbonylContact O-C 3.41Å; D17-N20 WeakPolarHBondContact O-CA 3.2Å; D17-N20 PolarHBondContact O-N 3.44Å; D17-Q21 WeakPolarHBondContact O-CG 3.42Å; D17-Q21 PolarHBondContact O-N 2.83Å
18	K	71.7	Confident	68.6	Low	151 Å²	151	119.1 Å²	119.1	66%	0.657	61%	0.607	S	S	*	*	H	α-helix	trans	-61.9	-35.8	175.8	-172.4	176.5	-179.1	176.3	113.2	A14 F15 N20	A14-K18 VanDerWaalsContact O-CB 3.3Å; A14-K18 WeakPolarHBondContact O-CB 3.18Å; A14-K18 PolarHBondContact O-N 3Å; F15-K18 PolarHBondContact O-N 2.91Å; K18-N20 VanDerWaalsContact C-N 3.34Å
19	Q	68.1	Low	68.2	Low	114 Å²	114	120.9 Å²	120.9	53%	0.533	61%	0.611	S	S	.	*	H	α-helix	trans	-74.4	-26.6	173.1	-72.7	-174.1	-36.5	0	112.7	F15 L16 D17	F15-Q19 HydrophobicContact CD1-CG 4.5Å; F15-Q19 HydrophobicContact CE1-CG 4.21Å; F15-Q19 VanDerWaalsContact CE1-NE2 3.27Å; F15-Q19 HydrophobicContact CZ-CG 4.36Å; F15-Q19 VanDerWaalsContact CZ-NE2 3.26Å; F15-Q19 WeakPolarHBondContact O-CG 3.32Å; F15-Q19 PolarHBondContact O-N 3.42Å; L16-Q19 PolarHBondContact O-N 3.46Å; D17-Q19 VanDerWaalsContact C-N 3.31Å; D17-Q19 PolarHBondContact O-N 3.49Å
20	N	63.9	Low	67.8	Low	58 Å²	58	124.7 Å²	124.7	31%	0.31	63%	0.628	S	S	.	*	H	α-helix	trans	-89.1	-18.7	179.4	-151.6	35.6	0	0	112.8	L16 D17 K18 V22 K23 F24	L16-N20 WeakPolarHBondContact O-CB 3.39Å; L16-N20 PolarHBondContact O-N 2.93Å; D17-N20 CarbonylContact O-C 3.41Å; D17-N20 WeakPolarHBondContact O-CA 3.2Å; D17-N20 PolarHBondContact O-N 3.44Å; K18-N20 VanDerWaalsContact C-N 3.34Å; N20-V22 PolarHBondContact O-N 2.96Å; N20-K23 WeakPolarHBondContact O-CB 3.32Å; N20-K23 PolarHBondContact O-N 3.05Å; N20-F24 HydrophobicContact CB-CD2 4.49Å; N20-F24 HydrophobicContact CB-CE2 4.09Å; N20-F24 WeakPolarHBondContact ND2-CE2 3.47Å; N20-F24 WeakPolarHBondContact ND2-CZ 3.13Å; N20-F24 WeakPolarHBondContact O-CD2 3.17Å; N20-F24 PolarHBondContact O-N 2.92Å
21	Q	62.5	Low	67.5	Low	125 Å²	125	125.7 Å²	125.7	58%	0.584	63%	0.631	S	S	*	*	H	α-helix	trans	-57.2	-33.1	175.1	-86.4	-173.3	-81.6	0	112.3	D17 K23	D17-Q21 WeakPolarHBondContact O-CG 3.42Å; D17-Q21 PolarHBondContact O-N 2.83Å; Q21-K23 PolarHBondContact O-N 3.18Å
22	V	60	Low	67	Low	121 Å²	121	124.9 Å²	124.9	73%	0.733	63%	0.632	S	S	*	*	H	α-helix	trans	-70.2	-21.9	177.1	-158.7	0	0	0	111.9	N20	N20-V22 PolarHBondContact O-N 2.96Å
23	K	59.7	Low	66.4	Low	150 Å²	150	123.4 Å²	123.4	65%	0.652	64%	0.635	S	S	*	*	H	α-helix	trans	-91.3	-23.7	-178.7	-66.3	-166.1	175.1	-148.2	113.8	N20 Q21	N20-K23 WeakPolarHBondContact O-CB 3.32Å; N20-K23 PolarHBondContact O-N 3.05Å; Q21-K23 PolarHBondContact O-N 3.18Å
24	F	59.8	Low	65.8	Low	134 Å²	134	122.1 Å²	122.1	59%	0.588	64%	0.637	S	S	*	*	H	α-helix	trans	-83.2	-16.1	179.1	-70	-66.5	0	0	114.3	N20 S26	N20-F24 HydrophobicContact CB-CD2 4.49Å; N20-F24 HydrophobicContact CB-CE2 4.09Å; N20-F24 WeakPolarHBondContact ND2-CE2 3.47Å; N20-F24 WeakPolarHBondContact ND2-CZ 3.13Å; N20-F24 WeakPolarHBondContact O-CD2 3.17Å; N20-F24 PolarHBondContact O-N 2.92Å; F24-S26 PolarHBondContact O-N 3.41Å
25	G	58.2	Low	65.1	Low	73 Å²	73	126.9 Å²	126.9	75%	0.753	65%	0.649	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.4	6	174.4	0	0	0	0	115.2
26	S	63.2	Low	64.2	Low	106 Å²	106	127.2 Å²	127.2	74%	0.741	66%	0.658	S	S	*	*	T	Hydrogen-bonded Turn	trans	-125.9	23.7	178	-69.7	0	0	0	113.3	F24	F24-S26 PolarHBondContact O-N 3.41Å
27	Y	63.1	Low	63.1	Low	202 Å²	202	130.8 Å²	130.8	79%	0.792	68%	0.676	S	S	*	*			trans	-98.5	94.7	158.9	-94.7	-88.4	0	0	108.5
28	L	54.7	Low	62.2	Low	243 Å²	243	134.3 Å²	134.3	100%	1.272	69%	0.692	S	S	*	*			trans	70.9	0	168.8	-65.9	159.9	0	0	117.2

Retrieved 28 of 28 residues in 41.7 ms (Link to these results)

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