A0A023IQJ5_HUMAN Loading...

Integrin a4 subunit

AlphaFold DB , UniProt , Accession A0A023IQJ5, Species HUMAN (Homo sapiens, Human), Gene ITGA4, Length 24 aa.

						>A0A023IQJ5_HUMAN|A0A023IQJ5|ITGA4
YNITTNKYKAFLDKQNQVKFGSYL
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	Y	50.7	Low	68.4	Low	279 Å²	279	136.9 Å²	136.9	100%	1.094	66%	0.661	S	S	*	*				0	94.5	0	-77.3	-92.6	0	0	108.7	I3	Y1-I3 PolarHBondContact O-N 3.42Å
2	N	52.8	Low	69.5	Low	125 Å²	125	132.8 Å²	132.8	67%	0.668	64%	0.644	S	S	*	*			trans	-72.6	121.8	-175.9	-75.7	38.1	0	0	110.3	T4 T5	N2-T4 PolarHBondContact O-N 3.5Å; N2-T4 VanDerWaalsContact O-N 3.11Å; N2-T5 PolarHBondContact O-N 2.84Å
3	I	63.2	Low	70.2	Confident	152 Å²	152	129.6 Å²	129.6	78%	0.779	63%	0.632	S	S	*	*	H	α-helix	trans	-55	-31.3	-177.9	-64.3	164.8	0	0	111.8	Y1 T5 N6 K7	Y1-I3 PolarHBondContact O-N 3.42Å; I3-T5 PolarHBondContact O-N 3.19Å; I3-N6 PolarHBondContact O-N 3.39Å; I3-K7 PolarHBondContact O-N 2.77Å
4	T	63.7	Low	70.8	Confident	114 Å²	114	131 Å²	131	70%	0.699	63%	0.633	S	S	*	*	H	α-helix	trans	-64.1	-38.6	177.6	-40.7	0	0	0	113.1	N2 N6 K7 Y8	N2-T4 PolarHBondContact O-N 3.5Å; N2-T4 VanDerWaalsContact O-N 3.11Å; T4-N6 VanDerWaalsContact C-N 3.34Å; T4-K7 PolarHBondContact O-N 3.26Å; T4-Y8 PolarHBondContact O-N 3.21Å
5	T	65.4	Low	71.4	Confident	77 Å²	77	129.3 Å²	129.3	47%	0.472	62%	0.624	S	S	.	*	H	α-helix	trans	-70.4	-32.6	179	-54.1	0	0	0	111.7	N2 I3 K9	N2-T5 PolarHBondContact O-N 2.84Å; I3-T5 PolarHBondContact O-N 3.19Å; T5-K9 HydrophobicContact CG2-CD 4.19Å; T5-K9 PolarHBondContact O-N 3.01Å; T5-K9 WeakPolarHBondContact O-CG 3.32Å; T5-K9 WeakPolarHBondContact O-CB 3.03Å
6	N	67.4	Low	71.5	Confident	117 Å²	117	126.2 Å²	126.2	63%	0.626	61%	0.612	S	S	*	*	H	α-helix	trans	-67.3	-43.5	177.4	-167	-16.8	0	0	111	I3 T4 Y8 K9 A10	I3-N6 PolarHBondContact O-N 3.39Å; T4-N6 VanDerWaalsContact C-N 3.34Å; N6-Y8 PolarHBondContact O-N 2.81Å; N6-K9 PolarHBondContact O-N 2.82Å; N6-A10 WeakPolarHBondContact O-CB 3.39Å; N6-A10 PolarHBondContact O-N 2.78Å
7	K	73.6	Confident	71.6	Confident	171 Å²	171	126.5 Å²	126.5	74%	0.743	61%	0.612	S	S	*	*	H	α-helix	trans	-64.2	-41.7	178.2	-158.9	179.1	-162.1	178.6	112.8	I3 T4 A10 F11	I3-K7 PolarHBondContact O-N 2.77Å; T4-K7 PolarHBondContact O-N 3.26Å; K7-A10 PolarHBondContact O-N 3.14Å; K7-F11 PolarHBondContact O-N 2.96Å; K7-F11 WeakPolarHBondContact O-CB 3.43Å
8	Y	76.4	Confident	71.3	Confident	160 Å²	160	125.2 Å²	125.2	63%	0.627	61%	0.612	S	S	*	*	H	α-helix	trans	-65.4	-44.2	176.9	-176.5	-98.6	0	0	111.8	T4 N6 A10 F11 L12	T4-Y8 PolarHBondContact O-N 3.21Å; N6-Y8 PolarHBondContact O-N 2.81Å; Y8-A10 PolarHBondContact O-N 3.46Å; Y8-F11 PolarHBondContact O-N 3.46Å; Y8-L12 WeakPolarHBondContact O-CB 3.28Å; Y8-L12 PolarHBondContact O-N 3.05Å
9	K	78.4	Confident	71.1	Confident	137 Å²	137	126.5 Å²	126.5	60%	0.596	61%	0.614	S	S	*	*	H	α-helix	trans	-61.5	-42.5	174.6	-76.6	178.5	175.7	-108.3	112.1	T5 N6 L12 D13	T5-K9 HydrophobicContact CG2-CD 4.19Å; T5-K9 PolarHBondContact O-N 3.01Å; T5-K9 WeakPolarHBondContact O-CG 3.32Å; T5-K9 WeakPolarHBondContact O-CB 3.03Å; N6-K9 PolarHBondContact O-N 2.82Å; K9-L12 PolarHBondContact O-N 3.34Å; K9-D13 WeakPolarHBondContact O-CB 3.23Å; K9-D13 PolarHBondContact O-N 3.5Å; K9-D13 VanDerWaalsContact O-CB 3.23Å
10	A	78.6	Confident	70.7	Confident	52 Å²	52	126.1 Å²	126.1	43%	0.43	61%	0.61	S	S	.	*	H	α-helix	trans	-66.7	-36.6	177.9	0	0	0	0	113.1	N6 K7 Y8 K14	N6-A10 WeakPolarHBondContact O-CB 3.39Å; N6-A10 PolarHBondContact O-N 2.78Å; K7-A10 PolarHBondContact O-N 3.14Å; Y8-A10 PolarHBondContact O-N 3.46Å; A10-K14 WeakPolarHBondContact O-CB 3.2Å; A10-K14 PolarHBondContact O-N 3.43Å
11	F	82.2	Confident	70.2	Confident	122 Å²	122	122.9 Å²	122.9	54%	0.535	61%	0.609	S	S	.	*	H	α-helix	trans	-66.7	-46.3	173.7	-178.9	-99.1	0	0	111.3	K7 Y8 K14 Q15	K7-F11 PolarHBondContact O-N 2.96Å; K7-F11 WeakPolarHBondContact O-CB 3.43Å; Y8-F11 PolarHBondContact O-N 3.46Å; F11-K14 PolarHBondContact O-N 3.36Å; F11-Q15 PolarHBondContact O-N 3.46Å; F11-Q15 WeakPolarHBondContact O-CG 3.39Å; F11-Q15 WeakPolarHBondContact O-CB 3.27Å; F11-Q15 VanDerWaalsContact CZ-NE2 3.33Å; F11-Q15 VanDerWaalsContact CZ-CD 3.45Å; F11-Q15 HydrophobicContact CZ-CG 4.11Å; F11-Q15 HydrophobicContact CD1-CG 4.41Å; F11-Q15 HydrophobicContact CE1-CG 4.08Å; F11-Q15 HydrophobicContact CE2-CG 4.47Å
12	L	81.8	Confident	70.8	Confident	87 Å²	87	114.3 Å²	114.3	46%	0.455	59%	0.591	S	S	.	*	H	α-helix	trans	-61.8	-45.9	177.1	-169.6	75.9	0	0	111.1	Y8 K9 Q15 N16	Y8-L12 WeakPolarHBondContact O-CB 3.28Å; Y8-L12 PolarHBondContact O-N 3.05Å; K9-L12 PolarHBondContact O-N 3.34Å; L12-Q15 PolarHBondContact O-N 3.06Å; L12-N16 WeakPolarHBondContact O-CB 3.27Å; L12-N16 PolarHBondContact O-N 2.88Å
13	D	78.4	Confident	71.2	Confident	92 Å²	92	117.8 Å²	117.8	49%	0.492	60%	0.596	S	S	.	*	H	α-helix	trans	-60.9	-45.8	178.8	-172.4	-102.2	0	0	111.9	K9 Q15 N16 Q17	K9-D13 WeakPolarHBondContact O-CB 3.23Å; K9-D13 PolarHBondContact O-N 3.5Å; K9-D13 VanDerWaalsContact O-CB 3.23Å; D13-Q15 PolarHBondContact O-N 3.27Å; D13-N16 CarbonylContact O-C 3.56Å; D13-N16 WeakPolarHBondContact O-CB 3.44Å; D13-N16 PolarHBondContact O-N 3.38Å; D13-N16 VanDerWaalsContact O-N 3.14Å; D13-Q17 WeakPolarHBondContact O-CG 3.38Å; D13-Q17 PolarHBondContact O-N 3.37Å
14	K	79.2	Confident	70.9	Confident	149 Å²	149	121.7 Å²	121.7	65%	0.648	62%	0.617	S	S	*	*	H	α-helix	trans	-62.7	-41.6	174.9	-176.4	174.9	-179.7	177.4	112.4	A10 F11 N16 V18	A10-K14 WeakPolarHBondContact O-CB 3.2Å; A10-K14 PolarHBondContact O-N 3.43Å; F11-K14 PolarHBondContact O-N 3.36Å; K14-N16 VanDerWaalsContact C-N 3.3Å; K14-V18 WeakPolarHBondContact O-CG2 3.47Å; K14-V18 PolarHBondContact O-N 2.98Å
15	Q	78.7	Confident	71.3	Confident	105 Å²	105	122.1 Å²	122.1	49%	0.491	61%	0.613	S	S	.	*	H	α-helix	trans	-66.8	-34.9	174.5	-74.1	-162.3	-43.7	0	111.9	F11 L12 D13 K19	F11-Q15 PolarHBondContact O-N 3.46Å; F11-Q15 WeakPolarHBondContact O-CG 3.39Å; F11-Q15 WeakPolarHBondContact O-CB 3.27Å; F11-Q15 VanDerWaalsContact CZ-NE2 3.33Å; F11-Q15 VanDerWaalsContact CZ-CD 3.45Å; F11-Q15 HydrophobicContact CZ-CG 4.11Å; F11-Q15 HydrophobicContact CD1-CG 4.41Å; F11-Q15 HydrophobicContact CE1-CG 4.08Å; F11-Q15 HydrophobicContact CE2-CG 4.47Å; L12-Q15 PolarHBondContact O-N 3.06Å; D13-Q15 PolarHBondContact O-N 3.27Å; Q15-K19 PolarHBondContact O-N 3.42Å; Q15-K19 VanDerWaalsContact O-CB 3.27Å; Q15-K19 WeakPolarHBondContact O-CB 3.39Å
16	N	73.3	Confident	71.6	Confident	80 Å²	80	124.4 Å²	124.4	43%	0.428	62%	0.62	S	S	.	*	H	α-helix	trans	-69.7	-43.2	177.5	-152.4	74.5	0	0	110.8	L12 D13 K14 V18 K19 F20	L12-N16 WeakPolarHBondContact O-CB 3.27Å; L12-N16 PolarHBondContact O-N 2.88Å; D13-N16 CarbonylContact O-C 3.56Å; D13-N16 WeakPolarHBondContact O-CB 3.44Å; D13-N16 PolarHBondContact O-N 3.38Å; D13-N16 VanDerWaalsContact O-N 3.14Å; K14-N16 VanDerWaalsContact C-N 3.3Å; N16-V18 VanDerWaalsContact C-N 3.33Å; N16-V18 PolarHBondContact O-N 2.94Å; N16-K19 PolarHBondContact O-N 3.03Å; N16-F20 PolarHBondContact O-N 3.11Å; N16-F20 WeakPolarHBondContact OD1-CE2 3.37Å; N16-F20 WeakPolarHBondContact OD1-CD2 3.41Å; N16-F20 WeakPolarHBondContact O-CD2 3.47Å; N16-F20 VanDerWaalsContact O-CD2 3.27Å; N16-F20 WeakPolarHBondContact O-CB 3.48Å; N16-F20 WeakPolarHBondContact ND2-CD2 3.34Å; N16-F20 VanDerWaalsContact CG-CD2 3.44Å; N16-F20 HydrophobicContact CB-CD2 4.39Å
17	Q	73.1	Confident	71.8	Confident	131 Å²	131	124.8 Å²	124.8	61%	0.612	62%	0.62	S	S	*	*	H	α-helix	trans	-58.9	-41.9	174.5	-78.8	-173.7	-26.7	0	112.5	D13 G21	D13-Q17 WeakPolarHBondContact O-CG 3.38Å; D13-Q17 PolarHBondContact O-N 3.37Å; Q17-G21 VanDerWaalsContact O-CA 3.28Å; Q17-G21 WeakPolarHBondContact O-CA 3.35Å; Q17-G21 PolarHBondContact O-N 3.49Å
18	V	66.9	Low	71.7	Confident	103 Å²	103	122.1 Å²	122.1	62%	0.624	61%	0.612	S	S	*	*	H	α-helix	trans	-69.2	-38.9	176.3	175.7	0	0	0	111.3	K14 N16	K14-V18 WeakPolarHBondContact O-CG2 3.47Å; K14-V18 PolarHBondContact O-N 2.98Å; N16-V18 VanDerWaalsContact C-N 3.33Å; N16-V18 PolarHBondContact O-N 2.94Å
19	K	66.7	Low	71.4	Confident	150 Å²	150	119.8 Å²	119.8	65%	0.652	61%	0.612	S	S	*	*	H	α-helix	trans	-73.7	-32.9	-177.5	-165.6	178.8	-177	-168.7	113.4	Q15 N16	Q15-K19 PolarHBondContact O-N 3.42Å; Q15-K19 VanDerWaalsContact O-CB 3.27Å; Q15-K19 WeakPolarHBondContact O-CB 3.39Å; N16-K19 PolarHBondContact O-N 3.03Å
20	F	63.4	Low	71	Confident	118 Å²	118	118.6 Å²	118.6	52%	0.518	61%	0.613	S	S	.	*	H	α-helix	trans	-105.7	-15.8	-176.5	-69.7	-83.5	0	0	113.7	N16 S22 Y23	N16-F20 PolarHBondContact O-N 3.11Å; N16-F20 WeakPolarHBondContact OD1-CE2 3.37Å; N16-F20 WeakPolarHBondContact OD1-CD2 3.41Å; N16-F20 WeakPolarHBondContact O-CD2 3.47Å; N16-F20 VanDerWaalsContact O-CD2 3.27Å; N16-F20 WeakPolarHBondContact O-CB 3.48Å; N16-F20 WeakPolarHBondContact ND2-CD2 3.34Å; N16-F20 VanDerWaalsContact CG-CD2 3.44Å; N16-F20 HydrophobicContact CB-CD2 4.39Å; F20-S22 VanDerWaalsContact C-N 3.28Å; F20-S22 PolarHBondContact O-N 3.3Å; F20-Y23 PolarHBondContact O-N 3.48Å
21	G	61.5	Low	70.4	Confident	59 Å²	59	123.4 Å²	123.4	61%	0.608	63%	0.626	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75.8	-13.6	173.4	0	0	0	0	114.2	Q17 Y23	Q17-G21 VanDerWaalsContact O-CA 3.28Å; Q17-G21 WeakPolarHBondContact O-CA 3.35Å; Q17-G21 PolarHBondContact O-N 3.49Å; G21-Y23 VanDerWaalsContact C-N 3.34Å
22	S	63.4	Low	69.5	Low	100 Å²	100	123.5 Å²	123.5	70%	0.699	63%	0.633	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91.6	8.5	172.6	-58.8	0	0	0	113.6	F20 L24	F20-S22 VanDerWaalsContact C-N 3.28Å; F20-S22 PolarHBondContact O-N 3.3Å; S22-L24 VanDerWaalsContact C-N 3.3Å
23	Y	60.7	Low	68.5	Low	198 Å²	198	126.5 Å²	126.5	78%	0.776	65%	0.647	S	S	*	*			trans	-93.3	25.5	174.7	-98.5	-86	0	0	113.2	F20 G21	F20-Y23 PolarHBondContact O-N 3.48Å; G21-Y23 VanDerWaalsContact C-N 3.34Å
24	L	56.8	Low	67.6	Low	233 Å²	233	129.6 Å²	129.6	100%	1.22	66%	0.661	S	S	*	*			trans	-125	0	168.8	-150.1	81.5	0	0	110.5	S22	S22-L24 VanDerWaalsContact C-N 3.3Å

Retrieved 24 of 24 residues in 53.7 ms (Link to these results)

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