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Cytochrome c oxidase subunit 1

Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

AlphaFold DB , UniProt , Accession A0A023Q488, Species HUMAN (Homo sapiens, Human), Gene COX1, Length 510 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	D	85.9	Confident	95.6	Very high	162 Å²	162	65.3 Å²	65.3	87%	0.866	31%	0.309	S	S	*	.				0	-70	0	-53.2	-16.5	0	0	0	113	W3 F5	D1-W3 PolarHBondContact O-N 3.47Å; D1-F5 CarbonylContact O-C 3.58Å; D1-F5 VanDerWaalsContact O-C 3.28Å; D1-F5 WeakPolarHBondContact O-CA 3.26Å; D1-F5 PolarHBondContact O-N 2.87Å
2	R	92.1	Very high	95.9	Very high	111 Å²	111	59.8 Å²	59.8	42%	0.419	28%	0.283	S	S	.	.	T	Hydrogen-bonded Turn	trans	-53.4	-42.5	-171.3	-177	175.7	167.7	-158.8	-8.9	117.2	S6 D11 Y499	R2-S6 WeakPolarHBondContact O-CA 3.36Å; R2-S6 WeakPolarHBondContact O-CB 3.23Å; R2-S6 PolarHBondContact O-OG 2.96Å; R2-D11 WeakPolarHBondContact CG-OD2 3.15Å; R2-D11 IonicContact CZ-OD1 2.78Å; R2-D11 IonicContact NE-OD1 3.74Å; R2-D11 PolarHBondContact NE-OD1 2.67Å; R2-D11 VanDerWaalsContact NE-OD1 3.07Å; R2-D11 IonicContact NE-OD2 3.37Å; R2-D11 PolarHBondContact NE-OD2 3.26Å; R2-D11 VanDerWaalsContact NE-OD2 3.12Å; R2-D11 IonicContact NH2-OD1 2.61Å; R2-D11 PolarHBondContact NH2-OD1 2.76Å; R2-Y499 VanDerWaalsContact CZ-CE1 3.44Å; R2-Y499 VanDerWaalsContact CZ-CZ 3.48Å; R2-Y499 PolarHBondContact NH1-OH 2.96Å; R2-Y499 PolarHBondContact NH2-OH 2.91Å; R2-Y499 VanDerWaalsContact NH2-OH 3.11Å
3	W	95.4	Very high	96.1	Very high	114 Å²	114	55.2 Å²	55.2	43%	0.432	26%	0.261	S	S	.	.	T	Hydrogen-bonded Turn	trans	-94.4	-51.3	-173.8	-60.8	112.2	0	0	0	113.1	D1 D11 L15	D1-W3 PolarHBondContact O-N 3.47Å; W3-D11 HydrophobicContact CE3-CB 4.25Å; W3-D11 HydrophobicContact CZ3-CB 4.01Å; W3-L15 HydrophobicContact CE3-CD2 4.08Å; W3-L15 HydrophobicContact CE3-CG 4.2Å
4	L	95.4	Very high	96.3	Very high	90 Å²	90	53.9 Å²	53.9	47%	0.471	26%	0.258	S	S	.	.	T	Hydrogen-bonded Turn	trans	-72.9	-41.2	-177.2	-174.4	63	0	0	0	112.8	N96 W100	L4-N96 PolarHBondContact O-ND2 3.31Å; L4-W100 HydrophobicContact CD1-CD2 4.34Å; L4-W100 HydrophobicContact CD1-CH2 3.74Å; L4-W100 HydrophobicContact CD1-CZ2 3.5Å; L4-W100 VanDerWaalsContact CD1-CZ2 3.5Å; L4-W100 HydrophobicContact CD1-CZ3 4.26Å; L4-W100 PolarHBondContact O-NE1 3.26Å
5	F	96.8	Very high	96.4	Very high	143 Å²	143	51.9 Å²	51.9	63%	0.627	25%	0.25	S	C	*	.	T	Hydrogen-bonded Turn	trans	-108.4	31.6	-179.6	-54.4	-45.4	0	0	0	111	D1	D1-F5 CarbonylContact O-C 3.58Å; D1-F5 VanDerWaalsContact O-C 3.28Å; D1-F5 WeakPolarHBondContact O-CA 3.26Å; D1-F5 PolarHBondContact O-N 2.87Å
6	S	96.9	Very high	96.6	Very high	5 Å²	5	49.4 Å²	49.4	4%	0.035	24%	0.237	C	C	.	.			trans	-62.3	145.6	179.8	-155.1	0	0	0	0	111.1	R2 N8 D11 N96	R2-S6 WeakPolarHBondContact O-CA 3.36Å; R2-S6 WeakPolarHBondContact O-CB 3.23Å; R2-S6 PolarHBondContact O-OG 2.96Å; S6-N8 PolarHBondContact OG-N 2.8Å; S6-D11 VanDerWaalsContact OG-CB 3.32Å; S6-D11 WeakPolarHBondContact OG-CB 3.33Å; S6-N96 VanDerWaalsContact O-CB 3.28Å; S6-N96 WeakPolarHBondContact O-CB 3.21Å; S6-N96 VanDerWaalsContact O-CG 3.23Å
7	T	97.1	Very high	96.7	Very high	67 Å²	67	48.1 Å²	48.1	41%	0.411	23%	0.232	S	C	.	.			trans	-118.9	-5.8	162.2	54.5	0	0	0	0	111.5	D88 P92 R93	T7-D88 VanDerWaalsContact O-OD2 3.11Å; T7-P92 HydrophobicContact CG2-CB 4.23Å; T7-P92 WeakPolarHBondContact O-CB 3.4Å; T7-R93 HydrophobicContact CG2-CG 4.05Å
8	N	97.8	Very high	96.8	Very high	12 Å²	12	51.7 Å²	51.7	6%	0.064	25%	0.252	C	S	.	.			trans	-82.1	127.2	-174.9	-172.4	-73.5	0	0	0	110.9	S6 K10 D11 I12 Y499	S6-N8 PolarHBondContact OG-N 2.8Å; N8-K10 PolarHBondContact O-N 2.67Å; N8-K10 WeakPolarHBondContact OD1-CA 3.2Å; N8-K10 WeakPolarHBondContact OD1-CB 3.24Å; N8-K10 PolarHBondContact OD1-N 3.04Å; N8-D11 HydrophobicContact CB-CB 4.37Å; N8-D11 PolarHBondContact O-N 3.31Å; N8-I12 WeakPolarHBondContact O-CG1 3.3Å; N8-I12 PolarHBondContact O-N 3.28Å; N8-Y499 PolarHBondContact ND2-O 3.01Å
9	H	98	Very high	96.9	Very high	0 Å²	0	50.2 Å²	50.2	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-56.7	-30.1	178.7	71.2	101.7	0	0	0	114.8	G13 N77 P81 D88 M89	H9-G13 WeakPolarHBondContact O-CA 3.32Å; H9-G13 PolarHBondContact O-N 2.99Å; H9-N77 PolarHBondContact ND1-O 2.97Å; H9-P81 HydrophobicContact CB-CG 4.24Å; H9-D88 VanDerWaalsContact CB-OD1 3.28Å; H9-D88 WeakPolarHBondContact CB-OD1 3.22Å; H9-D88 IonicContact CD2-OD1 3.12Å; H9-D88 PolarHBondContact CD2-OD1 3.45Å; H9-D88 VanDerWaalsContact CD2-OD1 3.31Å; H9-D88 IonicContact CG-OD1 2.6Å; H9-D88 PolarHBondContact N-OD1 3.4Å; H9-M89 HydrophobicContact CB-CG 3.79Å
10	K	98.3	Very high	97	Very high	5 Å²	5	47.7 Å²	47.7	2%	0.022	23%	0.231	C	C	.	.	H	α-helix	trans	-74.3	-41.6	179.7	-56.4	165.9	-178	144.3	0	111.5	N8 T14 W78 P497 P498 Y499 T501	N8-K10 PolarHBondContact O-N 2.67Å; N8-K10 WeakPolarHBondContact OD1-CA 3.2Å; N8-K10 WeakPolarHBondContact OD1-CB 3.24Å; N8-K10 PolarHBondContact OD1-N 3.04Å; K10-T14 WeakPolarHBondContact O-CB 3.48Å; K10-T14 PolarHBondContact O-N 3.32Å; K10-T14 PolarHBondContact O-OG1 3.24Å; K10-W78 HydrophobicContact CB-CD2 4.21Å; K10-W78 HydrophobicContact CB-CE3 4.05Å; K10-W78 HydrophobicContact CB-CH2 3.73Å; K10-W78 HydrophobicContact CB-CZ2 3.87Å; K10-W78 HydrophobicContact CB-CZ3 3.82Å; K10-W78 HydrophobicContact CD-CZ3 4.07Å; K10-W78 HydrophobicContact CG-CD2 4.43Å; K10-W78 HydrophobicContact CG-CE3 3.87Å; K10-W78 HydrophobicContact CG-CH2 4.17Å; K10-W78 HydrophobicContact CG-CZ3 3.74Å; K10-W78 PolarHBondContact O-NE1 2.92Å; K10-P497 HydrophobicContact CD-CG 4.37Å; K10-P498 PolarHBondContact NZ-O 3.47Å; K10-Y499 PolarHBondContact NZ-O 3.19Å; K10-T501 PolarHBondContact NZ-OG1 2.86Å
11	D	98.3	Very high	97	Very high	9 Å²	9	48 Å²	48	5%	0.048	24%	0.241	C	C	.	.	H	α-helix	trans	-66	-46.7	175.6	-75.2	-25.2	0	0	0	110.2	R2 W3 S6 N8 T14 L15	R2-D11 WeakPolarHBondContact CG-OD2 3.15Å; R2-D11 IonicContact CZ-OD1 2.78Å; R2-D11 IonicContact NE-OD1 3.74Å; R2-D11 PolarHBondContact NE-OD1 2.67Å; R2-D11 VanDerWaalsContact NE-OD1 3.07Å; R2-D11 IonicContact NE-OD2 3.37Å; R2-D11 PolarHBondContact NE-OD2 3.26Å; R2-D11 VanDerWaalsContact NE-OD2 3.12Å; R2-D11 IonicContact NH2-OD1 2.61Å; R2-D11 PolarHBondContact NH2-OD1 2.76Å; W3-D11 HydrophobicContact CE3-CB 4.25Å; W3-D11 HydrophobicContact CZ3-CB 4.01Å; S6-D11 VanDerWaalsContact OG-CB 3.32Å; S6-D11 WeakPolarHBondContact OG-CB 3.33Å; N8-D11 HydrophobicContact CB-CB 4.37Å; N8-D11 PolarHBondContact O-N 3.31Å; D11-T14 WeakPolarHBondContact O-CB 3.27Å; D11-T14 PolarHBondContact O-N 2.84Å; D11-L15 WeakPolarHBondContact O-CG 3.34Å; D11-L15 PolarHBondContact O-N 3.19Å
12	I	98.6	Very high	97.6	Very high	0 Å²	0	47.5 Å²	47.5	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-63.4	-44.2	177	-64.1	165.6	0	0	0	111	N8 T14 L15 Y16 N95 N96 F99	N8-I12 WeakPolarHBondContact O-CG1 3.3Å; N8-I12 PolarHBondContact O-N 3.28Å; I12-T14 VanDerWaalsContact C-N 3.26Å; I12-T14 PolarHBondContact O-N 3.35Å; I12-L15 WeakPolarHBondContact O-CB 3.45Å; I12-L15 PolarHBondContact O-N 2.86Å; I12-L15 VanDerWaalsContact O-N 3.12Å; I12-Y16 HydrophobicContact CG2-CD2 3.83Å; I12-Y16 HydrophobicContact CG2-CE2 3.64Å; I12-Y16 VanDerWaalsContact O-CD2 3.29Å; I12-Y16 WeakPolarHBondContact O-CD2 3.26Å; I12-Y16 PolarHBondContact O-N 3.35Å; I12-N95 HydrophobicContact CD1-CB 4.07Å; I12-N96 HydrophobicContact CD1-CB 3.92Å; I12-F99 HydrophobicContact CG2-CB 4.14Å
13	G	98.4	Very high	98	Very high	0 Å²	0	42.2 Å²	42.2	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-58.9	-37.9	174.1	0	0	0	0	0	112.3	H9 Y16 L17 G74 W78	H9-G13 WeakPolarHBondContact O-CA 3.32Å; H9-G13 PolarHBondContact O-N 2.99Å; G13-Y16 PolarHBondContact O-N 3.44Å; G13-L17 WeakPolarHBondContact O-CG 3.4Å; G13-L17 PolarHBondContact O-N 3.08Å; G13-G74 WeakPolarHBondContact O-CA 3.44Å; G13-W78 VanDerWaalsContact C-CD1 3.49Å
14	T	98.6	Very high	98.1	Very high	36 Å²	36	37 Å²	37	22%	0.221	19%	0.19	C	C	.	.	H	α-helix	trans	-65.3	-42.1	174.2	-57.1	0	0	0	0	111.8	K10 D11 I12 Y16 L17 L18 W78	K10-T14 WeakPolarHBondContact O-CB 3.48Å; K10-T14 PolarHBondContact O-N 3.32Å; K10-T14 PolarHBondContact O-OG1 3.24Å; D11-T14 WeakPolarHBondContact O-CB 3.27Å; D11-T14 PolarHBondContact O-N 2.84Å; I12-T14 VanDerWaalsContact C-N 3.26Å; I12-T14 PolarHBondContact O-N 3.35Å; T14-Y16 VanDerWaalsContact C-N 3.34Å; T14-Y16 PolarHBondContact O-N 3.39Å; T14-L17 PolarHBondContact O-N 3.41Å; T14-L18 HydrophobicContact CG2-CD1 4.2Å; T14-L18 HydrophobicContact CG2-CG 4.43Å; T14-L18 WeakPolarHBondContact O-CG 3.36Å; T14-L18 PolarHBondContact O-N 2.8Å; T14-W78 VanDerWaalsContact OG1-CZ2 3.28Å; T14-W78 WeakPolarHBondContact OG1-CZ2 3.45Å; T14-W78 PolarHBondContact OG1-NE1 3.33Å; T14-W78 VanDerWaalsContact OG1-NE1 3.09Å
15	L	98.8	Very high	98.2	Very high	25 Å²	25	36.1 Å²	36.1	13%	0.131	19%	0.188	C	C	.	.	H	α-helix	trans	-60.4	-43	176	-70	174.5	0	0	0	111.7	W3 D11 I12 L18 F19 F99 W100	W3-L15 HydrophobicContact CE3-CD2 4.08Å; W3-L15 HydrophobicContact CE3-CG 4.2Å; D11-L15 WeakPolarHBondContact O-CG 3.34Å; D11-L15 PolarHBondContact O-N 3.19Å; I12-L15 WeakPolarHBondContact O-CB 3.45Å; I12-L15 PolarHBondContact O-N 2.86Å; I12-L15 VanDerWaalsContact O-N 3.12Å; L15-L18 PolarHBondContact O-N 3.11Å; L15-F19 VanDerWaalsContact O-CB 3.28Å; L15-F19 WeakPolarHBondContact O-CB 3.49Å; L15-F19 PolarHBondContact O-N 2.97Å; L15-F99 VanDerWaalsContact C-CE2 3.44Å; L15-F99 HydrophobicContact CB-CD1 4.09Å; L15-F99 HydrophobicContact CB-CD2 3.99Å; L15-F99 HydrophobicContact CB-CE1 3.77Å; L15-F99 HydrophobicContact CB-CE2 3.66Å; L15-F99 HydrophobicContact CB-CG 4.21Å; L15-F99 HydrophobicContact CB-CZ 3.56Å; L15-F99 HydrophobicContact CD1-CD1 3.94Å; L15-F99 HydrophobicContact CD1-CE1 3.82Å; L15-F99 HydrophobicContact CD1-CZ 4.45Å; L15-F99 HydrophobicContact CD2-CE1 4.47Å; L15-F99 HydrophobicContact CD2-CZ 4.5Å; L15-F99 HydrophobicContact CG-CE1 4.24Å; L15-F99 HydrophobicContact CG-CZ 4.39Å; L15-F99 WeakPolarHBondContact O-CE2 3.4Å; L15-W100 HydrophobicContact CD1-CZ2 4.5Å
16	Y	98.8	Very high	98.3	Very high	11 Å²	11	31.3 Å²	31.3	4%	0.043	17%	0.168	C	C	.	.	H	α-helix	trans	-60.4	-44.3	173.4	-85.1	-71.9	0	0	0	112.9	I12 G13 T14 G20 P69 G73 S98 F99 L102	I12-Y16 HydrophobicContact CG2-CD2 3.83Å; I12-Y16 HydrophobicContact CG2-CE2 3.64Å; I12-Y16 VanDerWaalsContact O-CD2 3.29Å; I12-Y16 WeakPolarHBondContact O-CD2 3.26Å; I12-Y16 PolarHBondContact O-N 3.35Å; G13-Y16 PolarHBondContact O-N 3.44Å; T14-Y16 VanDerWaalsContact C-N 3.34Å; T14-Y16 PolarHBondContact O-N 3.39Å; Y16-G20 PolarHBondContact O-N 2.81Å; Y16-P69 HydrophobicContact CD1-CB 4.05Å; Y16-G73 VanDerWaalsContact CB-C 3.4Å; Y16-G73 VanDerWaalsContact CD2-O 3.25Å; Y16-G73 WeakPolarHBondContact CD2-O 3.21Å; Y16-G73 VanDerWaalsContact CG-C 3.43Å; Y16-G73 VanDerWaalsContact CG-CA 3.44Å; Y16-S98 WeakPolarHBondContact OH-CB 3.43Å; Y16-S98 PolarHBondContact OH-OG 3.28Å; Y16-F99 AromaticContact CD1-CD2 3.88Å; Y16-F99 HydrophobicContact CD1-CD2 3.88Å; Y16-F99 HydrophobicContact CD2-CB 4.28Å; Y16-F99 HydrophobicContact CD2-CD2 4.07Å; Y16-F99 HydrophobicContact CE1-CB 4.35Å; Y16-F99 HydrophobicContact CE1-CD2 4.07Å; Y16-F99 HydrophobicContact CE2-CB 3.69Å; Y16-F99 HydrophobicContact CE2-CD2 4.23Å; Y16-F99 HydrophobicContact CE2-CG 4.42Å; Y16-F99 AromaticContact CG-CD2 3.88Å; Y16-F99 HydrophobicContact CG-CD2 3.88Å; Y16-F99 WeakPolarHBondContact OH-CA 3.37Å; Y16-F99 PolarHBondContact OH-N 3.46Å; Y16-L102 HydrophobicContact CD1-CD1 3.88Å; Y16-L102 HydrophobicContact CE1-CD1 3.45Å; Y16-L102 VanDerWaalsContact CE1-CD1 3.45Å
17	L	98.7	Very high	98.3	Very high	28 Å²	28	31 Å²	31	15%	0.147	17%	0.167	C	C	.	.	H	α-helix	trans	-62.7	-43.7	177.7	-70.3	175.1	0	0	0	111.9	G13 T14 A21 I70 F75 F397	G13-L17 WeakPolarHBondContact O-CG 3.4Å; G13-L17 PolarHBondContact O-N 3.08Å; T14-L17 PolarHBondContact O-N 3.41Å; L17-A21 VanDerWaalsContact O-CB 3.24Å; L17-A21 WeakPolarHBondContact O-CB 2.95Å; L17-A21 PolarHBondContact O-N 3.41Å; L17-I70 HydrophobicContact CD2-CG2 3.96Å; L17-F75 HydrophobicContact CD2-CE2 4.47Å; L17-F397 HydrophobicContact CD1-CD2 4.09Å; L17-F397 HydrophobicContact CD1-CE2 4.06Å
18	L	98.6	Very high	98.3	Very high	113 Å²	113	29.1 Å²	29.1	59%	0.592	16%	0.155	S	C	*	.	H	α-helix	trans	-66.6	-45.8	178.3	-69.3	175.5	0	0	0	112	T14 L15 A21 W22	T14-L18 HydrophobicContact CG2-CD1 4.2Å; T14-L18 HydrophobicContact CG2-CG 4.43Å; T14-L18 WeakPolarHBondContact O-CG 3.36Å; T14-L18 PolarHBondContact O-N 2.8Å; L15-L18 PolarHBondContact O-N 3.11Å; L18-A21 PolarHBondContact O-N 2.98Å; L18-W22 PolarHBondContact O-N 3.03Å
19	F	98.8	Very high	98.3	Very high	23 Å²	23	30.8 Å²	30.8	10%	0.101	17%	0.17	C	C	.	.	H	α-helix	trans	-59.6	-49.8	176.6	175.2	-95.3	0	0	0	111.3	L15 A21 W22 A23 F65 P69 F99 L102 P103 L106	L15-F19 VanDerWaalsContact O-CB 3.28Å; L15-F19 WeakPolarHBondContact O-CB 3.49Å; L15-F19 PolarHBondContact O-N 2.97Å; F19-A21 VanDerWaalsContact C-N 3.34Å; F19-A21 PolarHBondContact O-N 3.33Å; F19-W22 PolarHBondContact O-N 3.4Å; F19-A23 WeakPolarHBondContact O-CB 3.36Å; F19-A23 PolarHBondContact O-N 3.32Å; F19-F65 HydrophobicContact CE1-CB 4.16Å; F19-F65 AromaticContact CE1-CD1 3.93Å; F19-F65 HydrophobicContact CE1-CD1 3.93Å; F19-F65 HydrophobicContact CZ-CB 4.44Å; F19-F65 AromaticContact CZ-CD1 3.75Å; F19-F65 HydrophobicContact CZ-CD1 3.75Å; F19-P69 HydrophobicContact CD1-CB 4.12Å; F19-P69 HydrophobicContact CD1-CG 4.31Å; F19-P69 HydrophobicContact CE1-CG 4.22Å; F19-F99 HydrophobicContact CB-CE2 3.89Å; F19-F99 HydrophobicContact CB-CZ 4.42Å; F19-F99 HydrophobicContact CG-CE2 4.38Å; F19-L102 HydrophobicContact CD1-CB 4.44Å; F19-L102 HydrophobicContact CD1-CD1 4.24Å; F19-L102 HydrophobicContact CE1-CB 3.84Å; F19-L102 HydrophobicContact CE1-CD1 4.04Å; F19-L102 HydrophobicContact CE2-CB 4.43Å; F19-L102 HydrophobicContact CZ-CB 3.81Å; F19-P103 HydrophobicContact CD2-CG 4.31Å; F19-P103 HydrophobicContact CE2-CB 4.45Å; F19-P103 HydrophobicContact CE2-CG 4.22Å; F19-L106 HydrophobicContact CE2-CB 4.26Å; F19-L106 HydrophobicContact CE2-CD2 3.69Å; F19-L106 HydrophobicContact CZ-CB 3.93Å; F19-L106 HydrophobicContact CZ-CD2 3.62Å; F19-L106 HydrophobicContact CZ-CG 4.43Å
20	G	98.6	Very high	98.3	Very high	0 Å²	0	32 Å²	32	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-65.1	-36.1	179.7	0	0	0	0	0	113.1	Y16 G24 F65 M66	Y16-G20 PolarHBondContact O-N 2.81Å; G20-G24 PolarHBondContact O-N 3.49Å; G20-F65 WeakPolarHBondContact CA-O 3.44Å; G20-M66 WeakPolarHBondContact O-CG 3.34Å
21	A	98.1	Very high	98.3	Very high	53 Å²	53	33 Å²	33	44%	0.438	18%	0.184	S	C	.	.	H	α-helix	trans	-64.3	-44	173.3	0	0	0	0	0	111.8	L17 L18 F19 G24 V25	L17-A21 VanDerWaalsContact O-CB 3.24Å; L17-A21 WeakPolarHBondContact O-CB 2.95Å; L17-A21 PolarHBondContact O-N 3.41Å; L18-A21 PolarHBondContact O-N 2.98Å; F19-A21 VanDerWaalsContact C-N 3.34Å; F19-A21 PolarHBondContact O-N 3.33Å; A21-G24 PolarHBondContact O-N 3.4Å; A21-V25 PolarHBondContact O-N 3.19Å; A21-V25 VanDerWaalsContact O-N 3.08Å
22	W	98.4	Very high	98.3	Very high	152 Å²	152	33.8 Å²	33.8	58%	0.576	19%	0.188	S	C	*	.	H	α-helix	trans	-62.6	-48	176.2	-174.4	90.6	0	0	0	111.7	L18 F19 G24 V25 L26 L106 L110	L18-W22 PolarHBondContact O-N 3.03Å; F19-W22 PolarHBondContact O-N 3.4Å; W22-G24 VanDerWaalsContact C-N 3.27Å; W22-G24 PolarHBondContact O-N 3.31Å; W22-V25 PolarHBondContact O-N 2.83Å; W22-L26 HydrophobicContact CH2-CD2 4.02Å; W22-L26 HydrophobicContact CZ3-CD2 3.8Å; W22-L26 PolarHBondContact O-N 3.05Å; W22-L26 VanDerWaalsContact O-N 3.13Å; W22-L106 HydrophobicContact CE3-CD2 4.02Å; W22-L106 HydrophobicContact CZ3-CD2 3.64Å; W22-L110 HydrophobicContact CH2-CD1 4.34Å
23	A	98.6	Very high	98.3	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-61.3	-36.5	175.3	0	0	0	0	0	111.9	F19 L26 G27 V61 F65 L106	F19-A23 WeakPolarHBondContact O-CB 3.36Å; F19-A23 PolarHBondContact O-N 3.32Å; A23-L26 WeakPolarHBondContact O-CB 3.15Å; A23-L26 PolarHBondContact O-N 3.41Å; A23-G27 PolarHBondContact O-N 2.97Å; A23-V61 HydrophobicContact CB-CG1 4.28Å; A23-V61 WeakPolarHBondContact O-CG1 3.4Å; A23-F65 HydrophobicContact CB-CB 3.86Å; A23-F65 VanDerWaalsContact CB-O 3.3Å; A23-F65 WeakPolarHBondContact CB-O 3.2Å; A23-L106 HydrophobicContact CB-CD2 4.31Å
24	G	97.7	Very high	98.3	Very high	6 Å²	6	38.6 Å²	38.6	6%	0.062	21%	0.213	C	C	.	.	H	α-helix	trans	-63.9	-39.2	175.7	0	0	0	0	0	113.5	G20 A21 W22 G27 T28	G20-G24 PolarHBondContact O-N 3.49Å; A21-G24 PolarHBondContact O-N 3.4Å; W22-G24 VanDerWaalsContact C-N 3.27Å; W22-G24 PolarHBondContact O-N 3.31Å; G24-G27 PolarHBondContact O-N 3.04Å; G24-T28 WeakPolarHBondContact O-CB 3.33Å; G24-T28 PolarHBondContact O-N 3.4Å; G24-T28 PolarHBondContact O-OG1 2.79Å
25	V	98	Very high	98.2	Very high	70 Å²	70	37.5 Å²	37.5	42%	0.424	21%	0.205	S	C	.	.	H	α-helix	trans	-64	-43.7	172.9	173.9	0	0	0	0	110.5	A21 W22 T28 A29	A21-V25 PolarHBondContact O-N 3.19Å; A21-V25 VanDerWaalsContact O-N 3.08Å; W22-V25 PolarHBondContact O-N 2.83Å; V25-T28 PolarHBondContact O-N 3.26Å; V25-A29 PolarHBondContact O-N 3.07Å
26	L	98.4	Very high	98.1	Very high	42 Å²	42	37.9 Å²	37.9	22%	0.22	21%	0.212	C	C	.	.	H	α-helix	trans	-61	-47.6	175.4	177	60.1	0	0	0	112.1	W22 A23 T28 A29 L30 V61 L110	W22-L26 HydrophobicContact CH2-CD2 4.02Å; W22-L26 HydrophobicContact CZ3-CD2 3.8Å; W22-L26 PolarHBondContact O-N 3.05Å; W22-L26 VanDerWaalsContact O-N 3.13Å; A23-L26 WeakPolarHBondContact O-CB 3.15Å; A23-L26 PolarHBondContact O-N 3.41Å; L26-T28 VanDerWaalsContact C-N 3.28Å; L26-T28 PolarHBondContact O-N 2.86Å; L26-A29 WeakPolarHBondContact O-CB 3.44Å; L26-A29 PolarHBondContact O-N 3.12Å; L26-A29 VanDerWaalsContact O-N 3.15Å; L26-L30 WeakPolarHBondContact O-CG 3.35Å; L26-L30 PolarHBondContact O-N 2.75Å; L26-V61 HydrophobicContact CG-CG1 4.49Å; L26-L110 HydrophobicContact CD2-CD1 3.9Å; L26-L110 HydrophobicContact CD2-CD2 3.71Å; L26-L110 HydrophobicContact CD2-CG 4.41Å
27	G	98.1	Very high	98.1	Very high	0 Å²	0	37.5 Å²	37.5	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-61.8	-36	177	0	0	0	0	0	112.6	A23 G24 L30 S31 H58	A23-G27 PolarHBondContact O-N 2.97Å; G24-G27 PolarHBondContact O-N 3.04Å; G27-L30 PolarHBondContact O-N 3.22Å; G27-S31 PolarHBondContact O-N 2.96Å; G27-H58 PolarHBondContact O-ND1 3.06Å
28	T	97.1	Very high	98	Very high	27 Å²	27	36.2 Å²	36.2	17%	0.166	20%	0.203	C	C	.	.	H	α-helix	trans	-68.1	-39.4	173.6	-56.4	0	0	0	0	111.8	G24 V25 L26 L30 S31 L32 V462	G24-T28 WeakPolarHBondContact O-CB 3.33Å; G24-T28 PolarHBondContact O-N 3.4Å; G24-T28 PolarHBondContact O-OG1 2.79Å; V25-T28 PolarHBondContact O-N 3.26Å; L26-T28 VanDerWaalsContact C-N 3.28Å; L26-T28 PolarHBondContact O-N 2.86Å; T28-L30 VanDerWaalsContact C-N 3.32Å; T28-L30 PolarHBondContact O-N 3.34Å; T28-S31 PolarHBondContact O-N 3.47Å; T28-S31 PolarHBondContact O-OG 3.48Å; T28-L32 HydrophobicContact CG2-CD1 4.25Å; T28-L32 VanDerWaalsContact O-CG 3.3Å; T28-L32 WeakPolarHBondContact O-CG 3.46Å; T28-L32 PolarHBondContact O-N 2.61Å; T28-V462 HydrophobicContact CG2-CG2 4.33Å
29	A	98.2	Very high	97.8	Very high	46 Å²	46	31.5 Å²	31.5	38%	0.38	18%	0.183	S	C	.	.	H	α-helix	trans	-61.3	-42.5	174.5	0	0	0	0	0	111.4	V25 L26 L32 L33	V25-A29 PolarHBondContact O-N 3.07Å; L26-A29 WeakPolarHBondContact O-CB 3.44Å; L26-A29 PolarHBondContact O-N 3.12Å; L26-A29 VanDerWaalsContact O-N 3.15Å; A29-L32 PolarHBondContact O-N 2.72Å; A29-L33 PolarHBondContact O-N 3.39Å; A29-L33 VanDerWaalsContact O-N 3.14Å
30	L	98.4	Very high	97.6	Very high	25 Å²	25	35.8 Å²	35.8	13%	0.131	20%	0.203	C	C	.	.	H	α-helix	trans	-63.7	-40.7	175	-63.3	169.8	0	0	0	111.9	L26 G27 T28 L32 L33 I34 I54 A57 H58 V61	L26-L30 WeakPolarHBondContact O-CG 3.35Å; L26-L30 PolarHBondContact O-N 2.75Å; G27-L30 PolarHBondContact O-N 3.22Å; T28-L30 VanDerWaalsContact C-N 3.32Å; T28-L30 PolarHBondContact O-N 3.34Å; L30-L32 VanDerWaalsContact C-N 3.31Å; L30-L32 PolarHBondContact O-N 2.94Å; L30-L33 PolarHBondContact O-N 3.41Å; L30-I34 WeakPolarHBondContact O-CG1 3.4Å; L30-I34 PolarHBondContact O-N 3.27Å; L30-I34 VanDerWaalsContact O-N 3.12Å; L30-I54 HydrophobicContact CB-CG2 4.08Å; L30-I54 HydrophobicContact CD2-CG2 3.98Å; L30-I54 WeakPolarHBondContact O-CG2 3.4Å; L30-A57 HydrophobicContact CD1-CB 3.87Å; L30-H58 HydrophobicContact CB-CB 3.86Å; L30-H58 HydrophobicContact CD1-CB 4.47Å; L30-V61 HydrophobicContact CD1-CG2 4.36Å
31	S	98	Very high	97.4	Very high	26 Å²	26	37.7 Å²	37.7	18%	0.182	22%	0.215	C	C	.	.	H	α-helix	trans	-65.7	-34.6	177.3	76	0	0	0	0	112.9	G27 T28 I34 R35 H58	G27-S31 PolarHBondContact O-N 2.96Å; T28-S31 PolarHBondContact O-N 3.47Å; T28-S31 PolarHBondContact O-OG 3.48Å; S31-I34 WeakPolarHBondContact O-CB 3.19Å; S31-I34 PolarHBondContact O-N 3.24Å; S31-R35 WeakPolarHBondContact O-CG 3.49Å; S31-R35 PolarHBondContact O-N 3.06Å; S31-H58 VanDerWaalsContact CB-CE1 3.45Å; S31-H58 WeakPolarHBondContact CB-CE1 3.11Å
32	L	97.7	Very high	97.1	Very high	26 Å²	26	36.6 Å²	36.6	14%	0.136	21%	0.21	C	C	.	.	H	α-helix	trans	-66.7	-38.2	175	-72	165.3	0	0	0	112	T28 A29 L30 I34 R35 A36 F456 L459	T28-L32 HydrophobicContact CG2-CD1 4.25Å; T28-L32 VanDerWaalsContact O-CG 3.3Å; T28-L32 WeakPolarHBondContact O-CG 3.46Å; T28-L32 PolarHBondContact O-N 2.61Å; A29-L32 PolarHBondContact O-N 2.72Å; L30-L32 VanDerWaalsContact C-N 3.31Å; L30-L32 PolarHBondContact O-N 2.94Å; L32-I34 VanDerWaalsContact C-N 3.34Å; L32-R35 PolarHBondContact O-N 3.11Å; L32-A36 WeakPolarHBondContact O-CB 3.48Å; L32-A36 PolarHBondContact O-N 3.09Å; L32-F456 HydrophobicContact CD2-CD1 4.19Å; L32-F456 HydrophobicContact CD2-CE1 4.32Å; L32-L459 HydrophobicContact CD1-CB 4.17Å; L32-L459 HydrophobicContact CD1-CD1 3.84Å; L32-L459 HydrophobicContact CD1-CD2 3.72Å; L32-L459 HydrophobicContact CD1-CG 4.09Å; L32-L459 HydrophobicContact CD2-CB 4.16Å; L32-L459 HydrophobicContact CD2-CD2 4.36Å
33	L	97.9	Very high	96.6	Very high	80 Å²	80	33.3 Å²	33.3	42%	0.419	20%	0.203	S	C	.	.	H	α-helix	trans	-62.4	-43.2	173.2	-67.8	174.6	0	0	0	111.2	A29 L30 R35 A36 E37 I54	A29-L33 PolarHBondContact O-N 3.39Å; A29-L33 VanDerWaalsContact O-N 3.14Å; L30-L33 PolarHBondContact O-N 3.41Å; L33-R35 PolarHBondContact O-N 3Å; L33-A36 PolarHBondContact O-N 2.96Å; L33-E37 PolarHBondContact O-N 3.48Å; L33-I54 HydrophobicContact CB-CD1 4.43Å; L33-I54 HydrophobicContact CB-CG2 4.26Å; L33-I54 HydrophobicContact CD1-CD1 4.21Å
34	I	98.4	Very high	96.3	Very high	21 Å²	21	39.3 Å²	39.3	11%	0.108	24%	0.235	C	C	.	.	H	α-helix	trans	-59.6	-45.8	175.1	-63.9	163.8	0	0	0	110.7	L30 S31 L32 E37 L38 Y51 I54 V55 H58	L30-I34 WeakPolarHBondContact O-CG1 3.4Å; L30-I34 PolarHBondContact O-N 3.27Å; L30-I34 VanDerWaalsContact O-N 3.12Å; S31-I34 WeakPolarHBondContact O-CB 3.19Å; S31-I34 PolarHBondContact O-N 3.24Å; L32-I34 VanDerWaalsContact C-N 3.34Å; I34-E37 PolarHBondContact O-N 3.15Å; I34-L38 HydrophobicContact CG2-CD1 4Å; I34-L38 WeakPolarHBondContact O-CB 3.32Å; I34-L38 VanDerWaalsContact O-CG 3.32Å; I34-L38 WeakPolarHBondContact O-CG 3.21Å; I34-L38 PolarHBondContact O-N 3.15Å; I34-Y51 HydrophobicContact CB-CE2 4.44Å; I34-Y51 HydrophobicContact CG2-CE2 3.9Å; I34-I54 HydrophobicContact CD1-CG2 4.12Å; I34-I54 HydrophobicContact CG1-CG2 3.7Å; I34-V55 HydrophobicContact CD1-CB 4.32Å; I34-V55 HydrophobicContact CD1-CG2 3.79Å; I34-V55 HydrophobicContact CG1-CG2 3.89Å; I34-V55 HydrophobicContact CG2-CG2 4.39Å; I34-H58 HydrophobicContact CD1-CB 3.89Å
35	R	97.7	Very high	96.1	Very high	14 Å²	14	42 Å²	42	5%	0.053	25%	0.247	C	C	.	.	H	α-helix	trans	-75	-27.1	-179.5	-68	-46.7	-49.3	168.8	8.6	113.6	S31 L32 L33 G39 N448 S452	S31-R35 WeakPolarHBondContact O-CG 3.49Å; S31-R35 PolarHBondContact O-N 3.06Å; L32-R35 PolarHBondContact O-N 3.11Å; L33-R35 PolarHBondContact O-N 3Å; R35-G39 PolarHBondContact O-N 3.4Å; R35-G39 VanDerWaalsContact O-N 3.12Å; R35-N448 PolarHBondContact NH1-OD1 2.9Å; R35-N448 PolarHBondContact NH2-O 3.44Å; R35-N448 PolarHBondContact NH2-OD1 3.5Å; R35-S452 PolarHBondContact NE-OG 2.93Å; R35-S452 PolarHBondContact NH2-OG 2.9Å; R35-S452 WeakPolarHBondContact O-CB 3.41Å; R35-S452 PolarHBondContact O-OG 2.84Å
36	A	96.9	Very high	95.9	Very high	33 Å²	33	41.4 Å²	41.4	27%	0.273	26%	0.255	S	S	.	.	H	α-helix	trans	-68.6	-45.3	171.7	0	0	0	0	0	110.6	L32 L33 L38 G39 L44	L32-A36 WeakPolarHBondContact O-CB 3.48Å; L32-A36 PolarHBondContact O-N 3.09Å; L33-A36 PolarHBondContact O-N 2.96Å; A36-L38 VanDerWaalsContact C-N 3.33Å; A36-L38 PolarHBondContact O-N 3.3Å; A36-G39 PolarHBondContact O-N 2.96Å; A36-G39 VanDerWaalsContact O-N 3.15Å; A36-L44 HydrophobicContact CB-CD2 4.02Å
37	E	97.5	Very high	95.7	Very high	3 Å²	3	42.8 Å²	42.8	1%	0.014	26%	0.263	C	S	.	.	H	α-helix	trans	-56.1	-49.7	173.7	-170.5	65.3	-165.9	0	0	110.6	L33 I34 G39 N43 L44 L45 Y51	L33-E37 PolarHBondContact O-N 3.48Å; I34-E37 PolarHBondContact O-N 3.15Å; E37-G39 PolarHBondContact O-N 3.34Å; E37-N43 WeakPolarHBondContact OE1-CA 3.06Å; E37-L44 PolarHBondContact OE1-N 3.39Å; E37-L44 WeakPolarHBondContact OE2-CA 3.31Å; E37-L44 VanDerWaalsContact OE2-CB 3.22Å; E37-L44 WeakPolarHBondContact OE2-CB 3.41Å; E37-L44 PolarHBondContact OE2-N 3.08Å; E37-L45 HydrophobicContact CB-CD1 4.38Å; E37-L45 HydrophobicContact CG-CD1 4.33Å; E37-L45 PolarHBondContact OE1-N 3.14Å; E37-L45 VanDerWaalsContact OE2-CB 3.3Å; E37-L45 WeakPolarHBondContact OE2-CB 3.38Å; E37-L45 WeakPolarHBondContact OE2-CG 3.47Å; E37-L45 PolarHBondContact OE2-N 2.6Å; E37-Y51 HydrophobicContact CB-CD2 4.18Å; E37-Y51 HydrophobicContact CB-CE2 4.37Å; E37-Y51 HydrophobicContact CG-CD2 3.93Å; E37-Y51 HydrophobicContact CG-CE2 4.34Å
38	L	97.6	Very high	95.6	Very high	0 Å²	0	46.5 Å²	46.5	0%	0	28%	0.282	C	S	.	.	T	Hydrogen-bonded Turn	trans	-80	7.1	-177.9	-62.8	171.3	0	0	0	114.1	I34 A36 Q40 Y51 Y368 Y440 N448	I34-L38 HydrophobicContact CG2-CD1 4Å; I34-L38 WeakPolarHBondContact O-CB 3.32Å; I34-L38 VanDerWaalsContact O-CG 3.32Å; I34-L38 WeakPolarHBondContact O-CG 3.21Å; I34-L38 PolarHBondContact O-N 3.15Å; A36-L38 VanDerWaalsContact C-N 3.33Å; A36-L38 PolarHBondContact O-N 3.3Å; L38-Q40 VanDerWaalsContact C-N 3.3Å; L38-Q40 PolarHBondContact O-N 3.48Å; L38-Y51 HydrophobicContact CD1-CE2 4.44Å; L38-Y51 WeakPolarHBondContact CD1-OH 3.36Å; L38-Y51 HydrophobicContact CG-CE2 4.25Å; L38-Y368 WeakPolarHBondContact CD1-OH 3.49Å; L38-Y440 HydrophobicContact CB-CE1 4.13Å; L38-Y440 HydrophobicContact CD2-CD1 3.85Å; L38-Y440 HydrophobicContact CD2-CE1 3.99Å; L38-Y440 VanDerWaalsContact O-CE1 3.27Å; L38-Y440 WeakPolarHBondContact O-CE1 3.46Å; L38-Y440 PolarHBondContact O-OH 2.94Å; L38-N448 WeakPolarHBondContact O-CB 3.48Å
39	G	94.9	Very high	95.6	Very high	15 Å²	15	47.8 Å²	47.8	16%	0.155	29%	0.286	C	S	.	.	T	Hydrogen-bonded Turn	trans	-69.5	-26.6	-175.1	0	0	0	0	0	114	R35 A36 E37 I449	R35-G39 PolarHBondContact O-N 3.4Å; R35-G39 VanDerWaalsContact O-N 3.12Å; A36-G39 PolarHBondContact O-N 2.96Å; A36-G39 VanDerWaalsContact O-N 3.15Å; E37-G39 PolarHBondContact O-N 3.34Å; G39-I449 VanDerWaalsContact O-CG1 3.22Å; G39-I449 WeakPolarHBondContact O-CG1 3.33Å
40	Q	94.1	Very high	95.5	Very high	112 Å²	112	49.2 Å²	49.2	52%	0.523	29%	0.287	S	S	.	.	S	Bend	trans	-146.8	158.2	176.1	-68	-72.1	-40.8	0	0	108.4	L38 Y440	L38-Q40 VanDerWaalsContact C-N 3.3Å; L38-Q40 PolarHBondContact O-N 3.48Å; Q40-Y440 VanDerWaalsContact C-OH 3.27Å; Q40-Y440 WeakPolarHBondContact CA-OH 3.36Å; Q40-Y440 PolarHBondContact N-OH 3.22Å
41	P	94.4	Very high	95.5	Very high	40 Å²	40	48.2 Å²	48.2	26%	0.26	28%	0.281	S	S	.	.	S	Bend	trans	-59.6	148	166.8	-21.2	32	0	0	0	112.3	Y440 T445	P41-Y440 HydrophobicContact CG-CD2 4.33Å; P41-Y440 HydrophobicContact CG-CE2 3.76Å; P41-T445 HydrophobicContact CG-CG2 4.4Å; P41-T445 WeakPolarHBondContact CG-OG1 3.2Å
42	G	92.1	Very high	95.5	Very high	31 Å²	31	48.9 Å²	48.9	32%	0.32	28%	0.283	S	S	.	.	S	Bend	trans	94.9	164	-176.7	0	0	0	0	0	113.9	D439	G42-D439 PolarHBondContact N-OD1 3.04Å; G42-D439 PolarHBondContact N-OD2 2.81Å
43	N	87.2	Confident	95.5	Very high	83 Å²	83	48.3 Å²	48.3	44%	0.444	28%	0.28	S	S	.	.			trans	-88.1	120.3	-171.2	-67.1	-10.4	0	0	0	112.5	E37	E37-N43 WeakPolarHBondContact OE1-CA 3.06Å
44	L	92.9	Very high	95.5	Very high	126 Å²	126	45.4 Å²	45.4	66%	0.66	27%	0.265	S	S	*	.	S	Bend	trans	-89.4	-44.4	171	166.7	74.7	0	0	0	111	A36 E37 G46	A36-L44 HydrophobicContact CB-CD2 4.02Å; E37-L44 PolarHBondContact OE1-N 3.39Å; E37-L44 WeakPolarHBondContact OE2-CA 3.31Å; E37-L44 VanDerWaalsContact OE2-CB 3.22Å; E37-L44 WeakPolarHBondContact OE2-CB 3.41Å; E37-L44 PolarHBondContact OE2-N 3.08Å; L44-G46 VanDerWaalsContact C-N 3.32Å
45	L	93.4	Very high	95.6	Very high	62 Å²	62	45.6 Å²	45.6	33%	0.325	27%	0.268	S	S	.	.	S	Bend	trans	-74.4	-24	176.8	-74.7	169.9	0	0	0	112.2	E37 N47 I54	E37-L45 HydrophobicContact CB-CD1 4.38Å; E37-L45 HydrophobicContact CG-CD1 4.33Å; E37-L45 PolarHBondContact OE1-N 3.14Å; E37-L45 VanDerWaalsContact OE2-CB 3.3Å; E37-L45 WeakPolarHBondContact OE2-CB 3.38Å; E37-L45 WeakPolarHBondContact OE2-CG 3.47Å; E37-L45 PolarHBondContact OE2-N 2.6Å; L45-N47 PolarHBondContact O-N 2.68Å; L45-I54 HydrophobicContact CD1-CD1 3.88Å; L45-I54 HydrophobicContact CD2-CD1 4.49Å
46	G	93.3	Very high	95.6	Very high	57 Å²	57	45.1 Å²	45.1	59%	0.588	27%	0.266	S	S	*	.	S	Bend	trans	72.7	5.1	178.8	0	0	0	0	0	115.1	L44	L44-G46 VanDerWaalsContact C-N 3.32Å
47	N	94.8	Very high	95.7	Very high	71 Å²	71	44 Å²	44	38%	0.38	26%	0.257	S	S	.	.			trans	-149.5	113.3	179.3	-174.7	-34.8	0	0	0	112	L45 H49 I50 Y51	L45-N47 PolarHBondContact O-N 2.68Å; N47-H49 VanDerWaalsContact C-N 3.3Å; N47-H49 PolarHBondContact O-N 3.19Å; N47-H49 WeakPolarHBondContact OD1-CA 3.24Å; N47-H49 VanDerWaalsContact OD1-CB 3.28Å; N47-H49 WeakPolarHBondContact OD1-CB 3.46Å; N47-H49 PolarHBondContact OD1-N 3.4Å; N47-I50 HydrophobicContact CB-CB 4.2Å; N47-I50 HydrophobicContact CB-CD1 3.86Å; N47-I50 HydrophobicContact CB-CG1 3.97Å; N47-I50 PolarHBondContact O-N 2.83Å; N47-I50 PolarHBondContact OD1-N 3.25Å; N47-Y51 PolarHBondContact O-N 3Å
48	D	95.3	Very high	95.7	Very high	78 Å²	78	45.2 Å²	45.2	42%	0.417	26%	0.262	S	S	.	.	H	α-helix	trans	-64.5	-31.6	-178	-56.8	-21.7	0	0	0	113.2	Y51 N52 S438	D48-Y51 WeakPolarHBondContact O-CB 3.41Å; D48-Y51 PolarHBondContact O-N 3.01Å; D48-N52 PolarHBondContact O-N 3.24Å; D48-N52 VanDerWaalsContact O-N 3.09Å; D48-N52 PolarHBondContact O-ND2 3.47Å; D48-S438 WeakPolarHBondContact OD1-CB 3.46Å; D48-S438 PolarHBondContact OD1-OG 3.32Å
49	H	96.5	Very high	95.7	Very high	54 Å²	54	46.1 Å²	46.1	25%	0.25	27%	0.27	C	S	.	.	H	α-helix	trans	-67.7	-42.9	177.2	-175.1	70	0	0	0	111.1	N47 Y51 N52 V53 A117 G118 H135	N47-H49 VanDerWaalsContact C-N 3.3Å; N47-H49 PolarHBondContact O-N 3.19Å; N47-H49 WeakPolarHBondContact OD1-CA 3.24Å; N47-H49 VanDerWaalsContact OD1-CB 3.28Å; N47-H49 WeakPolarHBondContact OD1-CB 3.46Å; N47-H49 PolarHBondContact OD1-N 3.4Å; H49-Y51 VanDerWaalsContact C-N 3.27Å; H49-Y51 PolarHBondContact O-N 2.91Å; H49-N52 PolarHBondContact O-N 2.88Å; H49-N52 VanDerWaalsContact O-N 3.08Å; H49-V53 WeakPolarHBondContact O-CG2 3.37Å; H49-V53 PolarHBondContact O-N 3.35Å; H49-A117 PolarHBondContact CD2-O 2.78Å; H49-A117 WeakPolarHBondContact NE2-CB 3.24Å; H49-A117 PolarHBondContact NE2-O 2.82Å; H49-G118 PolarHBondContact NE2-O 3.45Å; H49-G118 VanDerWaalsContact NE2-O 3.12Å; H49-H135 AromaticContact CE1-CD2 3.99Å; H49-H135 AromaticContact CE1-NE2 3.45Å; H49-H135 PolarHBondContact CE1-NE2 2.71Å
50	I	97	Very high	95.9	Very high	76 Å²	76	45.4 Å²	45.4	39%	0.39	26%	0.263	S	S	.	.	H	α-helix	trans	-59.6	-41.8	175.3	-66.2	179.4	0	0	0	110.3	N47 N52 V53 I54	N47-I50 HydrophobicContact CB-CB 4.2Å; N47-I50 HydrophobicContact CB-CD1 3.86Å; N47-I50 HydrophobicContact CB-CG1 3.97Å; N47-I50 PolarHBondContact O-N 2.83Å; N47-I50 PolarHBondContact OD1-N 3.25Å; I50-N52 VanDerWaalsContact C-N 3.34Å; I50-N52 PolarHBondContact O-N 2.81Å; I50-V53 PolarHBondContact O-N 3.24Å; I50-I54 HydrophobicContact CG2-CD1 3.87Å; I50-I54 HydrophobicContact CG2-CG1 4.39Å; I50-I54 VanDerWaalsContact O-CG1 3.31Å; I50-I54 WeakPolarHBondContact O-CG1 3.28Å; I50-I54 PolarHBondContact O-N 3.34Å
51	Y	97.8	Very high	96.1	Very high	4 Å²	4	40.1 Å²	40.1	2%	0.016	24%	0.238	C	C	.	.	H	α-helix	trans	-56.8	-47	173.8	170.7	-94.6	0	0	0	111.8	I34 E37 L38 N47 D48 H49 V53 I54 V55 Y437	I34-Y51 HydrophobicContact CB-CE2 4.44Å; I34-Y51 HydrophobicContact CG2-CE2 3.9Å; E37-Y51 HydrophobicContact CB-CD2 4.18Å; E37-Y51 HydrophobicContact CB-CE2 4.37Å; E37-Y51 HydrophobicContact CG-CD2 3.93Å; E37-Y51 HydrophobicContact CG-CE2 4.34Å; L38-Y51 HydrophobicContact CD1-CE2 4.44Å; L38-Y51 WeakPolarHBondContact CD1-OH 3.36Å; L38-Y51 HydrophobicContact CG-CE2 4.25Å; N47-Y51 PolarHBondContact O-N 3Å; D48-Y51 WeakPolarHBondContact O-CB 3.41Å; D48-Y51 PolarHBondContact O-N 3.01Å; H49-Y51 VanDerWaalsContact C-N 3.27Å; H49-Y51 PolarHBondContact O-N 2.91Å; Y51-V53 VanDerWaalsContact C-N 3.35Å; Y51-V53 PolarHBondContact O-N 3.38Å; Y51-I54 PolarHBondContact O-N 2.91Å; Y51-V55 HydrophobicContact CD1-CG2 4.13Å; Y51-V55 HydrophobicContact CD2-CG2 4.41Å; Y51-V55 HydrophobicContact CE1-CG2 3.74Å; Y51-V55 HydrophobicContact CE2-CG2 4.05Å; Y51-V55 HydrophobicContact CG-CG2 4.46Å; Y51-V55 VanDerWaalsContact O-CG2 3.31Å; Y51-V55 WeakPolarHBondContact O-CG2 3.28Å; Y51-V55 PolarHBondContact O-N 3.46Å; Y51-Y437 VanDerWaalsContact CE1-O 3.23Å; Y51-Y437 WeakPolarHBondContact CE1-O 3.26Å; Y51-Y437 PolarHBondContact OH-O 3.31Å
52	N	98.1	Very high	96.3	Very high	41 Å²	41	39.5 Å²	39.5	22%	0.219	23%	0.232	C	C	.	.	H	α-helix	trans	-65.4	-34.6	178	-74.8	-41.6	0	0	0	113.4	D48 H49 I50 V55 T56 R436	D48-N52 PolarHBondContact O-N 3.24Å; D48-N52 VanDerWaalsContact O-N 3.09Å; D48-N52 PolarHBondContact O-ND2 3.47Å; H49-N52 PolarHBondContact O-N 2.88Å; H49-N52 VanDerWaalsContact O-N 3.08Å; I50-N52 VanDerWaalsContact C-N 3.34Å; I50-N52 PolarHBondContact O-N 2.81Å; N52-V55 PolarHBondContact O-N 3.09Å; N52-T56 VanDerWaalsContact O-CB 3.31Å; N52-T56 WeakPolarHBondContact O-CB 3.17Å; N52-T56 PolarHBondContact O-N 2.74Å; N52-T56 PolarHBondContact O-OG1 3.35Å; N52-R436 PolarHBondContact OD1-O 2.7Å
53	V	98.4	Very high	96.5	Very high	13 Å²	13	38.2 Å²	38.2	8%	0.079	22%	0.218	C	C	.	.	H	α-helix	trans	-63.6	-45	172.3	174.6	0	0	0	0	110.6	H49 I50 Y51 T56 A57 A113 A117	H49-V53 WeakPolarHBondContact O-CG2 3.37Å; H49-V53 PolarHBondContact O-N 3.35Å; I50-V53 PolarHBondContact O-N 3.24Å; Y51-V53 VanDerWaalsContact C-N 3.35Å; Y51-V53 PolarHBondContact O-N 3.38Å; V53-T56 PolarHBondContact O-N 3.19Å; V53-A57 VanDerWaalsContact O-CB 3.32Å; V53-A57 WeakPolarHBondContact O-CB 3.38Å; V53-A57 PolarHBondContact O-N 3.16Å; V53-A113 HydrophobicContact CG1-CB 3.87Å; V53-A117 WeakPolarHBondContact CG2-O 3.38Å
54	I	98.4	Very high	97	Very high	19 Å²	19	34.8 Å²	34.8	10%	0.097	20%	0.199	C	C	.	.	H	α-helix	trans	-63.3	-44.5	177.2	-66.6	168.3	0	0	0	110.7	L30 L33 I34 L45 I50 Y51 T56 A57 H58	L30-I54 HydrophobicContact CB-CG2 4.08Å; L30-I54 HydrophobicContact CD2-CG2 3.98Å; L30-I54 WeakPolarHBondContact O-CG2 3.4Å; L33-I54 HydrophobicContact CB-CD1 4.43Å; L33-I54 HydrophobicContact CB-CG2 4.26Å; L33-I54 HydrophobicContact CD1-CD1 4.21Å; I34-I54 HydrophobicContact CD1-CG2 4.12Å; I34-I54 HydrophobicContact CG1-CG2 3.7Å; L45-I54 HydrophobicContact CD1-CD1 3.88Å; L45-I54 HydrophobicContact CD2-CD1 4.49Å; I50-I54 HydrophobicContact CG2-CD1 3.87Å; I50-I54 HydrophobicContact CG2-CG1 4.39Å; I50-I54 VanDerWaalsContact O-CG1 3.31Å; I50-I54 WeakPolarHBondContact O-CG1 3.28Å; I50-I54 PolarHBondContact O-N 3.34Å; Y51-I54 PolarHBondContact O-N 2.91Å; I54-T56 VanDerWaalsContact C-N 3.33Å; I54-T56 PolarHBondContact O-N 3.41Å; I54-A57 PolarHBondContact O-N 2.96Å; I54-H58 VanDerWaalsContact O-CB 3.29Å; I54-H58 WeakPolarHBondContact O-CB 3.3Å; I54-H58 PolarHBondContact O-N 3.23Å
55	V	98.5	Very high	97.3	Very high	26 Å²	26	28.8 Å²	28.8	16%	0.158	17%	0.167	C	C	.	.	H	α-helix	trans	-59.5	-44.5	176	170.9	0	0	0	0	111.1	I34 Y51 N52 A59 R436	I34-V55 HydrophobicContact CD1-CB 4.32Å; I34-V55 HydrophobicContact CD1-CG2 3.79Å; I34-V55 HydrophobicContact CG1-CG2 3.89Å; I34-V55 HydrophobicContact CG2-CG2 4.39Å; Y51-V55 HydrophobicContact CD1-CG2 4.13Å; Y51-V55 HydrophobicContact CD2-CG2 4.41Å; Y51-V55 HydrophobicContact CE1-CG2 3.74Å; Y51-V55 HydrophobicContact CE2-CG2 4.05Å; Y51-V55 HydrophobicContact CG-CG2 4.46Å; Y51-V55 VanDerWaalsContact O-CG2 3.31Å; Y51-V55 WeakPolarHBondContact O-CG2 3.28Å; Y51-V55 PolarHBondContact O-N 3.46Å; N52-V55 PolarHBondContact O-N 3.09Å; V55-A59 PolarHBondContact O-N 3.18Å; V55-R436 HydrophobicContact CG1-CG 4.46Å
56	T	98.4	Very high	97.5	Very high	4 Å²	4	26.6 Å²	26.6	3%	0.025	16%	0.155	C	C	.	.	H	α-helix	trans	-64.7	-48.5	178.8	-57.6	0	0	0	0	111.1	N52 V53 I54 A59 F60 A119 G122	N52-T56 VanDerWaalsContact O-CB 3.31Å; N52-T56 WeakPolarHBondContact O-CB 3.17Å; N52-T56 PolarHBondContact O-N 2.74Å; N52-T56 PolarHBondContact O-OG1 3.35Å; V53-T56 PolarHBondContact O-N 3.19Å; I54-T56 VanDerWaalsContact C-N 3.33Å; I54-T56 PolarHBondContact O-N 3.41Å; T56-A59 PolarHBondContact O-N 3.18Å; T56-F60 HydrophobicContact CG2-CD2 3.77Å; T56-F60 HydrophobicContact CG2-CE2 3.49Å; T56-F60 VanDerWaalsContact CG2-CE2 3.49Å; T56-F60 VanDerWaalsContact O-CD2 3.3Å; T56-F60 WeakPolarHBondContact O-CD2 3.38Å; T56-F60 PolarHBondContact O-N 2.94Å; T56-F60 VanDerWaalsContact O-N 3.13Å; T56-A119 WeakPolarHBondContact CB-O 3.37Å; T56-A119 WeakPolarHBondContact CG2-O 3.45Å; T56-A119 PolarHBondContact OG1-O 3.31Å; T56-G122 WeakPolarHBondContact OG1-CA 3.43Å; T56-G122 PolarHBondContact OG1-N 2.83Å
57	A	98.5	Very high	97.8	Very high	9 Å²	9	24 Å²	24	7%	0.074	13%	0.128	C	C	.	.	H	α-helix	trans	-62.6	-43.6	177.9	0	0	0	0	0	112	L30 V53 I54 A59 F60 V61	L30-A57 HydrophobicContact CD1-CB 3.87Å; V53-A57 VanDerWaalsContact O-CB 3.32Å; V53-A57 WeakPolarHBondContact O-CB 3.38Å; V53-A57 PolarHBondContact O-N 3.16Å; I54-A57 PolarHBondContact O-N 2.96Å; A57-A59 VanDerWaalsContact C-N 3.35Å; A57-A59 PolarHBondContact O-N 3.14Å; A57-F60 PolarHBondContact O-N 3.12Å; A57-V61 VanDerWaalsContact O-CB 3.3Å; A57-V61 WeakPolarHBondContact O-CB 3.18Å; A57-V61 WeakPolarHBondContact O-CG2 3.37Å; A57-V61 PolarHBondContact O-N 2.98Å
58	H	98.4	Very high	97.9	Very high	28 Å²	28	21.1 Å²	21.1	13%	0.13	11%	0.113	C	C	.	.	H	α-helix	trans	-54.9	-50.9	176.8	168.8	66.9	0	0	0	111.1	G27 L30 S31 I34 I54 F60 V61 M62	G27-H58 PolarHBondContact O-ND1 3.06Å; L30-H58 HydrophobicContact CB-CB 3.86Å; L30-H58 HydrophobicContact CD1-CB 4.47Å; S31-H58 VanDerWaalsContact CB-CE1 3.45Å; S31-H58 WeakPolarHBondContact CB-CE1 3.11Å; I34-H58 HydrophobicContact CD1-CB 3.89Å; I54-H58 VanDerWaalsContact O-CB 3.29Å; I54-H58 WeakPolarHBondContact O-CB 3.3Å; I54-H58 PolarHBondContact O-N 3.23Å; H58-F60 PolarHBondContact O-N 2.85Å; H58-V61 PolarHBondContact O-N 2.95Å; H58-M62 WeakPolarHBondContact CE1-CG 3.43Å; H58-M62 WeakPolarHBondContact O-CB 3.44Å; H58-M62 VanDerWaalsContact O-CG 3.23Å; H58-M62 WeakPolarHBondContact O-CG 3.38Å; H58-M62 PolarHBondContact O-N 3.33Å
59	A	98.1	Very high	98	Very high	19 Å²	19	17.6 Å²	17.6	16%	0.157	9%	0.094	C	C	.	.	H	α-helix	trans	-61.4	-47.4	-178.9	0	0	0	0	0	111.9	V55 T56 A57 M62 I63 W123	V55-A59 PolarHBondContact O-N 3.18Å; T56-A59 PolarHBondContact O-N 3.18Å; A57-A59 VanDerWaalsContact C-N 3.35Å; A57-A59 PolarHBondContact O-N 3.14Å; A59-M62 PolarHBondContact O-N 2.89Å; A59-I63 WeakPolarHBondContact O-CB 3.29Å; A59-I63 WeakPolarHBondContact O-CG1 3.44Å; A59-I63 PolarHBondContact O-N 3.24Å; A59-W123 HydrophobicContact CB-CB 3.56Å; A59-W123 HydrophobicContact CB-CG 4.03Å
60	F	98.5	Very high	98.2	Very high	1 Å²	1	15.6 Å²	15.6	0%	0.004	9%	0.085	C	C	.	.	H	α-helix	trans	-64.4	-45.5	178.4	-74.8	-50.9	0	0	0	112.7	T56 A57 H58 M62 I63 F64 F65 L109 W123 V125 T143 L147	T56-F60 HydrophobicContact CG2-CD2 3.77Å; T56-F60 HydrophobicContact CG2-CE2 3.49Å; T56-F60 VanDerWaalsContact CG2-CE2 3.49Å; T56-F60 VanDerWaalsContact O-CD2 3.3Å; T56-F60 WeakPolarHBondContact O-CD2 3.38Å; T56-F60 PolarHBondContact O-N 2.94Å; T56-F60 VanDerWaalsContact O-N 3.13Å; A57-F60 PolarHBondContact O-N 3.12Å; H58-F60 PolarHBondContact O-N 2.85Å; F60-M62 PolarHBondContact O-N 3.18Å; F60-I63 PolarHBondContact O-N 3.19Å; F60-F64 AromaticContact CD1-CD2 3.75Å; F60-F64 HydrophobicContact CD1-CD2 3.75Å; F60-F64 AromaticContact CD1-CE2 3.71Å; F60-F64 HydrophobicContact CD1-CE2 3.71Å; F60-F64 HydrophobicContact CE1-CE2 4.08Å; F60-F64 PolarHBondContact O-N 2.97Å; F60-F65 WeakPolarHBondContact O-CD2 3.41Å; F60-L109 HydrophobicContact CB-CD1 4.08Å; F60-L109 HydrophobicContact CB-CD2 3.63Å; F60-L109 HydrophobicContact CD2-CD1 3.92Å; F60-L109 HydrophobicContact CG-CD1 4.28Å; F60-W123 HydrophobicContact CD1-CB 4.49Å; F60-W123 HydrophobicContact CE1-CB 4.18Å; F60-W123 WeakPolarHBondContact CE1-O 3.45Å; F60-W123 HydrophobicContact CE2-CB 4.49Å; F60-W123 HydrophobicContact CZ-CB 4.19Å; F60-W123 WeakPolarHBondContact CZ-O 3.32Å; F60-V125 HydrophobicContact CE2-CG2 4.2Å; F60-V125 HydrophobicContact CZ-CG2 3.63Å; F60-T143 HydrophobicContact CD2-CG2 4.19Å; F60-T143 HydrophobicContact CE2-CG2 3.58Å; F60-T143 HydrophobicContact CZ-CG2 4.03Å; F60-L147 HydrophobicContact CD1-CD2 3.77Å; F60-L147 HydrophobicContact CE1-CD1 3.74Å; F60-L147 HydrophobicContact CE1-CD2 3.77Å; F60-L147 HydrophobicContact CE1-CG 4.29Å; F60-L147 HydrophobicContact CZ-CD1 3.89Å
61	V	98.7	Very high	98.2	Very high	0 Å²	0	12.1 Å²	12.1	0%	0	7%	0.067	C	C	.	.	I	π-helix	trans	-59.1	-47.5	178.2	171.6	0	0	0	0	110.7	A23 L26 L30 A57 H58 F65 M66 L106 L109	A23-V61 HydrophobicContact CB-CG1 4.28Å; A23-V61 WeakPolarHBondContact O-CG1 3.4Å; L26-V61 HydrophobicContact CG-CG1 4.49Å; L30-V61 HydrophobicContact CD1-CG2 4.36Å; A57-V61 VanDerWaalsContact O-CB 3.3Å; A57-V61 WeakPolarHBondContact O-CB 3.18Å; A57-V61 WeakPolarHBondContact O-CG2 3.37Å; A57-V61 PolarHBondContact O-N 2.98Å; H58-V61 PolarHBondContact O-N 2.95Å; V61-F65 CarbonylContact O-C 3.28Å; V61-F65 WeakPolarHBondContact O-CA 3.46Å; V61-F65 WeakPolarHBondContact O-CB 3.28Å; V61-F65 PolarHBondContact O-N 3.24Å; V61-F65 VanDerWaalsContact O-N 3.11Å; V61-M66 PolarHBondContact O-N 3.03Å; V61-L106 HydrophobicContact CG2-CD1 4.23Å; V61-L109 HydrophobicContact CG2-CD2 3.78Å
62	M	98.3	Very high	98.1	Very high	27 Å²	27	12.8 Å²	12.8	13%	0.133	7%	0.071	C	C	.	.	I	π-helix	trans	-67.1	-43.7	-178.1	-68	-61.3	-71.4	0	0	112.4	H58 A59 F60 M66 V67	H58-M62 WeakPolarHBondContact CE1-CG 3.43Å; H58-M62 WeakPolarHBondContact O-CB 3.44Å; H58-M62 VanDerWaalsContact O-CG 3.23Å; H58-M62 WeakPolarHBondContact O-CG 3.38Å; H58-M62 PolarHBondContact O-N 3.33Å; A59-M62 PolarHBondContact O-N 2.89Å; F60-M62 PolarHBondContact O-N 3.18Å; M62-M66 HydrophobicContact CE-CE 4.46Å; M62-M66 HydrophobicContact CE-SD 3.34Å; M62-M66 WeakPolarHBondContact CE-SD 3.13Å; M62-M66 WeakPolarHBondContact O-CB 3.28Å; M62-M66 HydrophobicContact SD-SD 3.72Å; M62-V67 WeakPolarHBondContact O-CB 3.35Å; M62-V67 VanDerWaalsContact O-CG2 3.23Å; M62-V67 WeakPolarHBondContact O-CG2 3.45Å; M62-V67 PolarHBondContact O-N 3.42Å
63	I	96.8	Very high	98.1	Very high	5 Å²	5	11 Å²	11	3%	0.026	6%	0.063	C	C	.	.	I	π-helix	trans	-75.4	-59.5	-176.4	-65.8	170.1	0	0	0	110.7	A59 F60 M68 W123 L243	A59-I63 WeakPolarHBondContact O-CB 3.29Å; A59-I63 WeakPolarHBondContact O-CG1 3.44Å; A59-I63 PolarHBondContact O-N 3.24Å; F60-I63 PolarHBondContact O-N 3.19Å; I63-M68 HydrophobicContact CG2-CE 4.23Å; I63-M68 PolarHBondContact O-N 3.42Å; I63-M68 VanDerWaalsContact O-N 3.16Å; I63-W123 HydrophobicContact CD1-CE3 4.18Å; I63-W123 HydrophobicContact CD1-CZ3 4.24Å; I63-L243 HydrophobicContact CG1-CD1 4.43Å; I63-L243 HydrophobicContact CG2-CD1 3.86Å; I63-L243 HydrophobicContact CG2-CD2 4.17Å
64	F	98.1	Very high	98.1	Very high	11 Å²	11	10.4 Å²	10.4	5%	0.048	6%	0.059	C	C	.	.	I	π-helix	trans	-86.9	-23.1	-167.7	-65	-89.6	0	0	0	114.1	F60 M68 P69 L147 F235	F60-F64 AromaticContact CD1-CD2 3.75Å; F60-F64 HydrophobicContact CD1-CD2 3.75Å; F60-F64 AromaticContact CD1-CE2 3.71Å; F60-F64 HydrophobicContact CD1-CE2 3.71Å; F60-F64 HydrophobicContact CE1-CE2 4.08Å; F60-F64 PolarHBondContact O-N 2.97Å; F64-M68 HydrophobicContact CB-CE 4.05Å; F64-M68 HydrophobicContact CD1-CE 3.07Å; F64-M68 HydrophobicContact CE1-CE 3.54Å; F64-M68 HydrophobicContact CG-CE 3.69Å; F64-M68 HydrophobicContact CZ-CE 4.49Å; F64-P69 VanDerWaalsContact O-CD 3.23Å; F64-P69 WeakPolarHBondContact O-CD 3.41Å; F64-P69 WeakPolarHBondContact O-CG 3.5Å; F64-L147 HydrophobicContact CD1-CD2 4.39Å; F64-L147 HydrophobicContact CD2-CD2 4.08Å; F64-L147 HydrophobicContact CE1-CD2 4.43Å; F64-L147 HydrophobicContact CE2-CD2 4.08Å; F64-L147 HydrophobicContact CG-CD2 4.25Å; F64-L147 HydrophobicContact CZ-CD2 4.28Å; F64-F235 HydrophobicContact CE1-CZ 4.02Å; F64-F235 HydrophobicContact CZ-CE1 4.22Å; F64-F235 AromaticContact CZ-CZ 3.92Å; F64-F235 HydrophobicContact CZ-CZ 3.92Å
65	F	98.6	Very high	98.1	Very high	0 Å²	0	9.6 Å²	9.6	0%	0	6%	0.055	C	C	.	.	I	π-helix	trans	-115.7	-19.1	-172.9	-60.1	-78.9	0	0	0	114.3	F19 G20 A23 F60 V61 P69 S105 L106 L109 A150	F19-F65 HydrophobicContact CE1-CB 4.16Å; F19-F65 AromaticContact CE1-CD1 3.93Å; F19-F65 HydrophobicContact CE1-CD1 3.93Å; F19-F65 HydrophobicContact CZ-CB 4.44Å; F19-F65 AromaticContact CZ-CD1 3.75Å; F19-F65 HydrophobicContact CZ-CD1 3.75Å; G20-F65 WeakPolarHBondContact CA-O 3.44Å; A23-F65 HydrophobicContact CB-CB 3.86Å; A23-F65 VanDerWaalsContact CB-O 3.3Å; A23-F65 WeakPolarHBondContact CB-O 3.2Å; F60-F65 WeakPolarHBondContact O-CD2 3.41Å; V61-F65 CarbonylContact O-C 3.28Å; V61-F65 WeakPolarHBondContact O-CA 3.46Å; V61-F65 WeakPolarHBondContact O-CB 3.28Å; V61-F65 PolarHBondContact O-N 3.24Å; V61-F65 VanDerWaalsContact O-N 3.11Å; F65-P69 WeakPolarHBondContact O-CG 3.5Å; F65-S105 VanDerWaalsContact CE1-OG 3.28Å; F65-S105 WeakPolarHBondContact CE1-OG 3.47Å; F65-S105 WeakPolarHBondContact CZ-OG 3.26Å; F65-L106 HydrophobicContact CB-CD1 4.25Å; F65-L106 HydrophobicContact CD1-CB 3.74Å; F65-L106 HydrophobicContact CD1-CD1 4.11Å; F65-L106 HydrophobicContact CD1-CG 4.34Å; F65-L106 HydrophobicContact CD2-CD1 4.08Å; F65-L106 HydrophobicContact CE1-CB 3.72Å; F65-L106 HydrophobicContact CE1-CD1 4.46Å; F65-L106 HydrophobicContact CE2-CD1 4.46Å; F65-L106 HydrophobicContact CG-CB 4.38Å; F65-L106 HydrophobicContact CG-CD1 3.86Å; F65-L106 HydrophobicContact CZ-CB 4.37Å; F65-L109 HydrophobicContact CD2-CD2 3.95Å; F65-L109 HydrophobicContact CE2-CB 4.46Å; F65-L109 HydrophobicContact CE2-CD2 3.61Å; F65-A150 HydrophobicContact CZ-CB 4.44Å
66	M	98.2	Very high	98.1	Very high	15 Å²	15	8.3 Å²	8.3	7%	0.074	5%	0.047	C	C	.	.	I	π-helix	trans	-105.1	-68.9	172	-179.1	-154.7	171.2	0	0	111.6	G20 V61 M62 I70 V383	G20-M66 WeakPolarHBondContact O-CG 3.34Å; V61-M66 PolarHBondContact O-N 3.03Å; M62-M66 HydrophobicContact CE-CE 4.46Å; M62-M66 HydrophobicContact CE-SD 3.34Å; M62-M66 WeakPolarHBondContact CE-SD 3.13Å; M62-M66 WeakPolarHBondContact O-CB 3.28Å; M62-M66 HydrophobicContact SD-SD 3.72Å; M66-I70 HydrophobicContact CE-CD1 4.28Å; M66-I70 HydrophobicContact CG-CD1 3.84Å; M66-I70 WeakPolarHBondContact O-CB 3.41Å; M66-I70 VanDerWaalsContact O-CG1 3.23Å; M66-I70 WeakPolarHBondContact O-CG1 3.38Å; M66-I70 PolarHBondContact O-N 3.35Å; M66-V383 HydrophobicContact CE-CG1 4.41Å; M66-V383 HydrophobicContact CE-CG2 4.31Å
67	V	98.2	Very high	98.1	Very high	2 Å²	2	8.2 Å²	8.2	1%	0.012	5%	0.046	C	C	.	.	I	π-helix	trans	-64.6	-52.5	-166.6	174	0	0	0	0	111.7	M62 I70 M71 L243 A382	M62-V67 WeakPolarHBondContact O-CB 3.35Å; M62-V67 VanDerWaalsContact O-CG2 3.23Å; M62-V67 WeakPolarHBondContact O-CG2 3.45Å; M62-V67 PolarHBondContact O-N 3.42Å; V67-I70 PolarHBondContact O-N 3.19Å; V67-M71 HydrophobicContact CG1-CE 3.29Å; V67-M71 WeakPolarHBondContact O-CB 3.39Å; V67-M71 PolarHBondContact O-N 3.47Å; V67-L243 HydrophobicContact CB-CD2 4.15Å; V67-L243 HydrophobicContact CG1-CB 4.29Å; V67-L243 HydrophobicContact CG1-CD2 3.61Å; V67-L243 HydrophobicContact CG1-CG 4.49Å; V67-A382 HydrophobicContact CG1-CB 3.85Å; V67-A382 HydrophobicContact CG2-CB 4.5Å
68	M	97.1	Very high	98.1	Very high	12 Å²	12	8.3 Å²	8.3	6%	0.059	5%	0.045	C	C	.	.	H	α-helix	trans	-60.4	-51.5	177.8	-92.3	-163.6	-80.4	0	0	112.9	I63 F64 I70 M71 I72 G73 L192 E239 I242 L243	I63-M68 HydrophobicContact CG2-CE 4.23Å; I63-M68 PolarHBondContact O-N 3.42Å; I63-M68 VanDerWaalsContact O-N 3.16Å; F64-M68 HydrophobicContact CB-CE 4.05Å; F64-M68 HydrophobicContact CD1-CE 3.07Å; F64-M68 HydrophobicContact CE1-CE 3.54Å; F64-M68 HydrophobicContact CG-CE 3.69Å; F64-M68 HydrophobicContact CZ-CE 4.49Å; M68-I70 VanDerWaalsContact C-N 3.33Å; M68-I70 PolarHBondContact O-N 2.9Å; M68-M71 PolarHBondContact O-N 3.43Å; M68-I72 PolarHBondContact O-N 2.99Å; M68-G73 PolarHBondContact O-N 3.31Å; M68-L192 HydrophobicContact SD-CD2 4.32Å; M68-E239 WeakPolarHBondContact CE-OE1 3.3Å; M68-I242 HydrophobicContact CG-CG2 4.48Å; M68-I242 HydrophobicContact SD-CG2 4.44Å; M68-L243 HydrophobicContact CG-CD2 3.67Å
69	P	98.6	Very high	98.1	Very high	4 Å²	4	7 Å²	7	3%	0.026	4%	0.039	C	C	.	.	I	π-helix	trans	-58.4	-39.3	177.2	-33.5	42.7	0	0	0	113.7	Y16 F19 F64 F65 G73 G74 L102	Y16-P69 HydrophobicContact CD1-CB 4.05Å; F19-P69 HydrophobicContact CD1-CB 4.12Å; F19-P69 HydrophobicContact CD1-CG 4.31Å; F19-P69 HydrophobicContact CE1-CG 4.22Å; F64-P69 VanDerWaalsContact O-CD 3.23Å; F64-P69 WeakPolarHBondContact O-CD 3.41Å; F64-P69 WeakPolarHBondContact O-CG 3.5Å; F65-P69 WeakPolarHBondContact O-CG 3.5Å; P69-G73 CarbonylContact O-C 3.57Å; P69-G73 VanDerWaalsContact O-C 3.28Å; P69-G73 WeakPolarHBondContact O-CA 3.07Å; P69-G73 PolarHBondContact O-N 3.49Å; P69-G73 VanDerWaalsContact O-N 3.16Å; P69-G74 PolarHBondContact O-N 3.49Å; P69-L102 HydrophobicContact CB-CD1 4.09Å; P69-L102 HydrophobicContact CG-CD1 3.71Å
70	I	98.8	Very high	98.1	Very high	12 Å²	12	6.1 Å²	6.1	6%	0.062	3%	0.031	C	C	.	.	I	π-helix	trans	-70.6	-49.8	178.9	-68	173.7	0	0	0	111.3	L17 M66 V67 M68 G74 F75 I386	L17-I70 HydrophobicContact CD2-CG2 3.96Å; M66-I70 HydrophobicContact CE-CD1 4.28Å; M66-I70 HydrophobicContact CG-CD1 3.84Å; M66-I70 WeakPolarHBondContact O-CB 3.41Å; M66-I70 VanDerWaalsContact O-CG1 3.23Å; M66-I70 WeakPolarHBondContact O-CG1 3.38Å; M66-I70 PolarHBondContact O-N 3.35Å; V67-I70 PolarHBondContact O-N 3.19Å; M68-I70 VanDerWaalsContact C-N 3.33Å; M68-I70 PolarHBondContact O-N 2.9Å; I70-G74 CarbonylContact O-C 3.57Å; I70-G74 VanDerWaalsContact O-CA 3.29Å; I70-G74 WeakPolarHBondContact O-CA 3.3Å; I70-G74 PolarHBondContact O-N 3.01Å; I70-F75 HydrophobicContact CG2-CD2 3.98Å; I70-F75 HydrophobicContact CG2-CE2 3.74Å; I70-F75 WeakPolarHBondContact O-CD2 3.25Å; I70-F75 PolarHBondContact O-N 3.44Å; I70-I386 HydrophobicContact CB-CD1 4.15Å; I70-I386 HydrophobicContact CG2-CB 4.38Å; I70-I386 HydrophobicContact CG2-CD1 3.91Å; I70-I386 HydrophobicContact CG2-CG1 3.82Å; I70-I386 HydrophobicContact CG2-CG2 3.69Å
71	M	97.4	Very high	98.1	Very high	2 Å²	2	6 Å²	6	1%	0.01	3%	0.031	C	C	.	.	I	π-helix	trans	-74.7	-50.9	-172.5	-80.5	-156.5	-99.8	0	0	113.8	V67 M68 F75 G76 L243 P246 M250 A382 I386	V67-M71 HydrophobicContact CG1-CE 3.29Å; V67-M71 WeakPolarHBondContact O-CB 3.39Å; V67-M71 PolarHBondContact O-N 3.47Å; M68-M71 PolarHBondContact O-N 3.43Å; M71-F75 WeakPolarHBondContact O-CB 3.4Å; M71-G76 PolarHBondContact O-N 3.04Å; M71-G76 VanDerWaalsContact O-N 3.14Å; M71-L243 WeakPolarHBondContact CE-O 3.43Å; M71-P246 HydrophobicContact CB-CB 4.14Å; M71-P246 HydrophobicContact CB-CG 4.47Å; M71-P246 HydrophobicContact SD-CB 4.02Å; M71-M250 HydrophobicContact CG-CE 3.79Å; M71-M250 HydrophobicContact SD-CE 3.58Å; M71-M250 VanDerWaalsContact SD-CE 3.58Å; M71-A382 HydrophobicContact CE-CB 3.33Å; M71-I386 HydrophobicContact CE-CD1 4.07Å; M71-I386 HydrophobicContact CE-CG1 4.25Å; M71-I386 HydrophobicContact CG-CD1 3.96Å; M71-I386 HydrophobicContact CG-CG1 3.63Å; M71-I386 HydrophobicContact SD-CG1 4.26Å
72	I	96.6	Very high	97.9	Very high	18 Å²	18	6.1 Å²	6.1	9%	0.092	3%	0.031	C	C	.	.	I	π-helix	trans	-88.8	-48.1	-178	-65.9	-61.1	0	0	0	110.3	M68 G76 F161 V185 T188 P246	M68-I72 PolarHBondContact O-N 2.99Å; I72-G76 VanDerWaalsContact O-CA 3.22Å; I72-G76 WeakPolarHBondContact O-CA 3.42Å; I72-G76 PolarHBondContact O-N 3.32Å; I72-F161 HydrophobicContact CG2-CD2 4.11Å; I72-F161 HydrophobicContact CG2-CE2 3.59Å; I72-F161 HydrophobicContact CG2-CZ 4.44Å; I72-F161 VanDerWaalsContact O-CZ 3.29Å; I72-F161 WeakPolarHBondContact O-CZ 3.41Å; I72-V185 HydrophobicContact CD1-CG1 4.4Å; I72-V185 HydrophobicContact CD1-CG2 4.38Å; I72-T188 HydrophobicContact CD1-CG2 3.53Å; I72-T188 HydrophobicContact CG1-CG2 3.91Å; I72-P246 HydrophobicContact CD1-CB 4.32Å; I72-P246 HydrophobicContact CD1-CG 3.44Å; I72-P246 VanDerWaalsContact CD1-CG 3.44Å; I72-P246 HydrophobicContact CG1-CG 4.17Å
73	G	97.6	Very high	97.8	Very high	5 Å²	5	4.9 Å²	4.9	5%	0.052	3%	0.025	C	C	.	.	I	π-helix	trans	-67.3	-48.9	179.8	0	0	0	0	0	113	Y16 M68 P69 N77	Y16-G73 VanDerWaalsContact CB-C 3.4Å; Y16-G73 VanDerWaalsContact CD2-O 3.25Å; Y16-G73 WeakPolarHBondContact CD2-O 3.21Å; Y16-G73 VanDerWaalsContact CG-C 3.43Å; Y16-G73 VanDerWaalsContact CG-CA 3.44Å; M68-G73 PolarHBondContact O-N 3.31Å; P69-G73 CarbonylContact O-C 3.57Å; P69-G73 VanDerWaalsContact O-C 3.28Å; P69-G73 WeakPolarHBondContact O-CA 3.07Å; P69-G73 PolarHBondContact O-N 3.49Å; P69-G73 VanDerWaalsContact O-N 3.16Å; G73-N77 WeakPolarHBondContact O-CB 3.3Å; G73-N77 PolarHBondContact O-ND2 3.04Å
74	G	98.5	Very high	97.7	Very high	0 Å²	0	4.7 Å²	4.7	0%	0	2%	0.024	C	C	.	.	I	π-helix	trans	-81.5	-71.9	-173.5	0	0	0	0	0	112.4	G13 P69 I70 G76 N77 W78	G13-G74 WeakPolarHBondContact O-CA 3.44Å; P69-G74 PolarHBondContact O-N 3.49Å; I70-G74 CarbonylContact O-C 3.57Å; I70-G74 VanDerWaalsContact O-CA 3.29Å; I70-G74 WeakPolarHBondContact O-CA 3.3Å; I70-G74 PolarHBondContact O-N 3.01Å; G74-G76 PolarHBondContact O-N 3.38Å; G74-N77 PolarHBondContact O-N 3.27Å; G74-W78 WeakPolarHBondContact O-CB 3.44Å; G74-W78 PolarHBondContact O-N 3.29Å
75	F	98.8	Very high	97.5	Very high	1 Å²	1	4.4 Å²	4.4	0%	0.004	2%	0.024	C	C	.	.	I	π-helix	trans	-62.4	-41.7	180	-72.6	-71.9	0	0	0	112.1	L17 I70 M71 W78 L79 F181 M250 I386 F390 W393 F397	L17-F75 HydrophobicContact CD2-CE2 4.47Å; I70-F75 HydrophobicContact CG2-CD2 3.98Å; I70-F75 HydrophobicContact CG2-CE2 3.74Å; I70-F75 WeakPolarHBondContact O-CD2 3.25Å; I70-F75 PolarHBondContact O-N 3.44Å; M71-F75 WeakPolarHBondContact O-CB 3.4Å; F75-W78 PolarHBondContact O-N 3.14Å; F75-L79 HydrophobicContact CB-CD1 4.25Å; F75-L79 HydrophobicContact CD1-CD1 3.89Å; F75-L79 VanDerWaalsContact O-CB 3.24Å; F75-L79 WeakPolarHBondContact O-CB 3.38Å; F75-L79 WeakPolarHBondContact O-CG 3.24Å; F75-L79 PolarHBondContact O-N 3.03Å; F75-F181 HydrophobicContact CB-CE2 4.38Å; F75-F181 HydrophobicContact CB-CZ 3.78Å; F75-M250 HydrophobicContact CB-SD 4.46Å; F75-M250 HydrophobicContact CD1-SD 4.22Å; F75-M250 HydrophobicContact CD2-CE 4.44Å; F75-M250 HydrophobicContact CD2-SD 3.72Å; F75-M250 HydrophobicContact CE1-SD 4.41Å; F75-M250 HydrophobicContact CE2-SD 3.92Å; F75-M250 HydrophobicContact CG-SD 3.88Å; F75-M250 HydrophobicContact CZ-SD 4.27Å; F75-I386 HydrophobicContact CE2-CG2 4.44Å; F75-F390 HydrophobicContact CZ-CB 4.27Å; F75-W393 AromaticContact CD1-CE3 3.92Å; F75-W393 HydrophobicContact CD1-CE3 3.92Å; F75-W393 HydrophobicContact CD1-CZ3 4.4Å; F75-W393 AromaticContact CE1-CE3 3.71Å; F75-W393 HydrophobicContact CE1-CE3 3.71Å; F75-W393 HydrophobicContact CE1-CZ3 4.4Å; F75-F397 HydrophobicContact CD1-CE2 4.15Å; F75-F397 AromaticContact CD1-CZ 3.77Å; F75-F397 HydrophobicContact CD1-CZ 3.77Å; F75-F397 AromaticContact CE1-CE2 3.67Å; F75-F397 HydrophobicContact CE1-CE2 3.67Å; F75-F397 AromaticContact CE1-CZ 3.73Å; F75-F397 HydrophobicContact CE1-CZ 3.73Å; F75-F397 HydrophobicContact CZ-CE2 4.48Å
76	G	98.6	Very high	97.4	Very high	0 Å²	0	4.4 Å²	4.4	0%	0	2%	0.024	C	C	.	.	I	π-helix	trans	-57.6	-53.1	177.7	0	0	0	0	0	112.2	M71 I72 G74 W78 V80 F161	M71-G76 PolarHBondContact O-N 3.04Å; M71-G76 VanDerWaalsContact O-N 3.14Å; I72-G76 VanDerWaalsContact O-CA 3.22Å; I72-G76 WeakPolarHBondContact O-CA 3.42Å; I72-G76 PolarHBondContact O-N 3.32Å; G74-G76 PolarHBondContact O-N 3.38Å; G76-W78 PolarHBondContact O-N 3.1Å; G76-V80 VanDerWaalsContact O-CB 3.24Å; G76-V80 WeakPolarHBondContact O-CB 3.44Å; G76-V80 WeakPolarHBondContact O-CG2 3.08Å; G76-V80 PolarHBondContact O-N 3.06Å; G76-F161 VanDerWaalsContact C-CE1 3.46Å
77	N	98.6	Very high	97.2	Very high	1 Å²	1	6.5 Å²	6.5	1%	0.005	4%	0.039	C	C	.	.	H	α-helix	trans	-66.2	-37.7	179.6	-80.1	-68.5	0	0	0	113.1	H9 G73 G74 P81 N95	H9-N77 PolarHBondContact ND1-O 2.97Å; G73-N77 WeakPolarHBondContact O-CB 3.3Å; G73-N77 PolarHBondContact O-ND2 3.04Å; G74-N77 PolarHBondContact O-N 3.27Å; N77-P81 WeakPolarHBondContact O-CD 3.45Å; N77-N95 PolarHBondContact OD1-ND2 3.37Å; N77-N95 PolarHBondContact OD1-OD1 3.49Å
78	W	98.1	Very high	97.1	Very high	12 Å²	12	7.5 Å²	7.5	5%	0.045	4%	0.044	C	C	.	.	H	α-helix	trans	-66	-50.2	176.8	-98	101.8	0	0	0	112.5	K10 G13 T14 G74 F75 G76 L82 F397 P497	K10-W78 HydrophobicContact CB-CD2 4.21Å; K10-W78 HydrophobicContact CB-CE3 4.05Å; K10-W78 HydrophobicContact CB-CH2 3.73Å; K10-W78 HydrophobicContact CB-CZ2 3.87Å; K10-W78 HydrophobicContact CB-CZ3 3.82Å; K10-W78 HydrophobicContact CD-CZ3 4.07Å; K10-W78 HydrophobicContact CG-CD2 4.43Å; K10-W78 HydrophobicContact CG-CE3 3.87Å; K10-W78 HydrophobicContact CG-CH2 4.17Å; K10-W78 HydrophobicContact CG-CZ3 3.74Å; K10-W78 PolarHBondContact O-NE1 2.92Å; G13-W78 VanDerWaalsContact C-CD1 3.49Å; T14-W78 VanDerWaalsContact OG1-CZ2 3.28Å; T14-W78 WeakPolarHBondContact OG1-CZ2 3.45Å; T14-W78 PolarHBondContact OG1-NE1 3.33Å; T14-W78 VanDerWaalsContact OG1-NE1 3.09Å; G74-W78 WeakPolarHBondContact O-CB 3.44Å; G74-W78 PolarHBondContact O-N 3.29Å; F75-W78 PolarHBondContact O-N 3.14Å; G76-W78 PolarHBondContact O-N 3.1Å; W78-L82 HydrophobicContact CE3-CD1 4.4Å; W78-L82 VanDerWaalsContact O-CD1 3.3Å; W78-L82 WeakPolarHBondContact O-CD1 3.49Å; W78-L82 VanDerWaalsContact O-CG 3.32Å; W78-L82 WeakPolarHBondContact O-CG 3.45Å; W78-F397 HydrophobicContact CB-CD1 4.45Å; W78-F397 HydrophobicContact CB-CE1 3.76Å; W78-F397 HydrophobicContact CB-CZ 4.34Å; W78-F397 AromaticContact CD2-CD1 3.59Å; W78-F397 HydrophobicContact CD2-CD1 3.59Å; W78-F397 AromaticContact CD2-CE1 3.82Å; W78-F397 HydrophobicContact CD2-CE1 3.82Å; W78-F397 AromaticContact CE2-CD1 3.93Å; W78-F397 AromaticContact CE3-CD1 3.72Å; W78-F397 HydrophobicContact CE3-CD1 3.72Å; W78-F397 HydrophobicContact CE3-CE1 4.04Å; W78-F397 AromaticContact CG-CD1 3.94Å; W78-F397 HydrophobicContact CG-CD1 3.94Å; W78-F397 AromaticContact CG-CE1 3.71Å; W78-F397 HydrophobicContact CG-CE1 3.71Å; W78-F397 HydrophobicContact CG-CZ 4.42Å; W78-F397 HydrophobicContact CH2-CD1 4.43Å; W78-F397 HydrophobicContact CZ2-CB 4.43Å; W78-F397 HydrophobicContact CZ2-CD1 4.35Å; W78-F397 HydrophobicContact CZ3-CD1 4.14Å; W78-P497 HydrophobicContact CZ3-CG 4.14Å
79	L	98.4	Very high	97.1	Very high	0 Å²	0	7.1 Å²	7.1	0%	0	4%	0.042	C	C	.	.	H	α-helix	trans	-95.4	-32.4	-163.2	-59.3	176.5	0	0	0	113.3	F75 L82 M83 F181 W393 L396 F397	F75-L79 HydrophobicContact CB-CD1 4.25Å; F75-L79 HydrophobicContact CD1-CD1 3.89Å; F75-L79 VanDerWaalsContact O-CB 3.24Å; F75-L79 WeakPolarHBondContact O-CB 3.38Å; F75-L79 WeakPolarHBondContact O-CG 3.24Å; F75-L79 PolarHBondContact O-N 3.03Å; L79-L82 PolarHBondContact O-N 2.82Å; L79-M83 HydrophobicContact CB-CE 4.05Å; L79-M83 HydrophobicContact CB-CG 4.46Å; L79-M83 HydrophobicContact CB-SD 4.1Å; L79-M83 HydrophobicContact CD1-CE 4.05Å; L79-M83 HydrophobicContact CD2-CE 4.36Å; L79-M83 HydrophobicContact CG-CE 4.39Å; L79-M83 VanDerWaalsContact O-CB 3.25Å; L79-M83 WeakPolarHBondContact O-CB 3.19Å; L79-M83 VanDerWaalsContact O-CG 3.27Å; L79-M83 WeakPolarHBondContact O-CG 3.29Å; L79-M83 PolarHBondContact O-N 3.5Å; L79-F181 HydrophobicContact CB-CD1 4.09Å; L79-F181 HydrophobicContact CB-CE1 3.75Å; L79-F181 HydrophobicContact CD1-CD1 4.32Å; L79-F181 HydrophobicContact CD1-CE1 4.01Å; L79-F181 HydrophobicContact CD1-CZ 4.29Å; L79-F181 HydrophobicContact CG-CE1 4.47Å; L79-W393 HydrophobicContact CD1-CD2 3.7Å; L79-W393 HydrophobicContact CD1-CE3 3.81Å; L79-W393 HydrophobicContact CD1-CG 4.34Å; L79-W393 HydrophobicContact CD1-CH2 4Å; L79-W393 HydrophobicContact CD1-CZ2 3.86Å; L79-W393 HydrophobicContact CD1-CZ3 3.97Å; L79-W393 HydrophobicContact CD2-CD2 4.25Å; L79-W393 HydrophobicContact CD2-CG 4.08Å; L79-L396 HydrophobicContact CD2-CD2 3.72Å; L79-F397 HydrophobicContact CD2-CE1 4.11Å; L79-F397 HydrophobicContact CD2-CZ 4.45Å
80	V	98.4	Very high	97.1	Very high	0 Å²	0	8.4 Å²	8.4	0%	0	5%	0.053	C	C	.	.	H	α-helix	trans	-60.4	-53.4	-174.6	169.3	0	0	0	0	111.9	G76 L82 M83 I84 F161 I165 F181 V185	G76-V80 VanDerWaalsContact O-CB 3.24Å; G76-V80 WeakPolarHBondContact O-CB 3.44Å; G76-V80 WeakPolarHBondContact O-CG2 3.08Å; G76-V80 PolarHBondContact O-N 3.06Å; V80-L82 VanDerWaalsContact C-N 3.28Å; V80-L82 PolarHBondContact O-N 3.39Å; V80-M83 PolarHBondContact O-N 2.81Å; V80-I84 HydrophobicContact CG1-CD1 4.41Å; V80-I84 WeakPolarHBondContact O-CG1 3.23Å; V80-I84 PolarHBondContact O-N 3.14Å; V80-I84 VanDerWaalsContact O-N 3.12Å; V80-F161 HydrophobicContact CB-CD1 4.41Å; V80-F161 HydrophobicContact CB-CE1 4.28Å; V80-F161 HydrophobicContact CG1-CD1 4.44Å; V80-F161 HydrophobicContact CG2-CD1 4.26Å; V80-F161 HydrophobicContact CG2-CE1 4.17Å; V80-I165 HydrophobicContact CG1-CD1 3.99Å; V80-I165 HydrophobicContact CG1-CG1 3.53Å; V80-F181 HydrophobicContact CG2-CE1 4.22Å; V80-V185 HydrophobicContact CG2-CB 4.11Å; V80-V185 HydrophobicContact CG2-CG1 3.97Å; V80-V185 HydrophobicContact CG2-CG2 4.11Å
81	P	97.3	Very high	97.1	Very high	0 Å²	0	11.7 Å²	11.7	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-59.7	-39.4	177.3	-26.7	38	0	0	0	112.4	H9 N77 I84 G85 A86 M89	H9-P81 HydrophobicContact CB-CG 4.24Å; N77-P81 WeakPolarHBondContact O-CD 3.45Å; P81-I84 PolarHBondContact O-N 3.35Å; P81-G85 PolarHBondContact O-N 3.33Å; P81-A86 HydrophobicContact CB-CB 4.29Å; P81-A86 PolarHBondContact O-N 3.3Å; P81-M89 HydrophobicContact CG-CG 3.96Å; P81-M89 HydrophobicContact CG-SD 3.47Å; P81-M89 WeakPolarHBondContact CG-SD 3.3Å
82	L	96.1	Very high	97.1	Very high	2 Å²	2	13.3 Å²	13.3	1%	0.01	8%	0.078	C	C	.	.	H	α-helix	trans	-64.8	-45.1	179.2	-67.8	-178.2	0	0	0	112.9	W78 L79 V80 I84 G85 L396 L489 E490 P497 F502	W78-L82 HydrophobicContact CE3-CD1 4.4Å; W78-L82 VanDerWaalsContact O-CD1 3.3Å; W78-L82 WeakPolarHBondContact O-CD1 3.49Å; W78-L82 VanDerWaalsContact O-CG 3.32Å; W78-L82 WeakPolarHBondContact O-CG 3.45Å; L79-L82 PolarHBondContact O-N 2.82Å; V80-L82 VanDerWaalsContact C-N 3.28Å; V80-L82 PolarHBondContact O-N 3.39Å; L82-I84 VanDerWaalsContact C-N 3.3Å; L82-I84 PolarHBondContact O-N 3.06Å; L82-G85 PolarHBondContact O-N 3.39Å; L82-L396 HydrophobicContact CD1-CD2 4.21Å; L82-L489 WeakPolarHBondContact O-CB 3.24Å; L82-E490 HydrophobicContact CB-CB 3.89Å; L82-E490 HydrophobicContact CD1-CB 4.36Å; L82-P497 HydrophobicContact CD1-CG 4.4Å; L82-F502 HydrophobicContact CD2-CE2 3.92Å
83	M	95.5	Very high	97.2	Very high	1 Å²	1	22.2 Å²	22.2	1%	0.005	11%	0.111	C	C	.	.	H	α-helix	trans	-74	-19.2	-177.2	-74.8	-178.1	175.3	0	0	113.4	L79 V80 P179 F181 V182 W393 E490	L79-M83 HydrophobicContact CB-CE 4.05Å; L79-M83 HydrophobicContact CB-CG 4.46Å; L79-M83 HydrophobicContact CB-SD 4.1Å; L79-M83 HydrophobicContact CD1-CE 4.05Å; L79-M83 HydrophobicContact CD2-CE 4.36Å; L79-M83 HydrophobicContact CG-CE 4.39Å; L79-M83 VanDerWaalsContact O-CB 3.25Å; L79-M83 WeakPolarHBondContact O-CB 3.19Å; L79-M83 VanDerWaalsContact O-CG 3.27Å; L79-M83 WeakPolarHBondContact O-CG 3.29Å; L79-M83 PolarHBondContact O-N 3.5Å; V80-M83 PolarHBondContact O-N 2.81Å; M83-P179 HydrophobicContact CB-CG 4.2Å; M83-F181 HydrophobicContact CE-CB 4.5Å; M83-F181 HydrophobicContact CE-CD1 4.4Å; M83-F181 HydrophobicContact SD-CB 3.99Å; M83-F181 HydrophobicContact SD-CD1 3.74Å; M83-F181 HydrophobicContact SD-CG 4.26Å; M83-V182 HydrophobicContact CB-CG2 3.71Å; M83-V182 HydrophobicContact SD-CG2 4.29Å; M83-W393 HydrophobicContact CE-CZ2 3.7Å; M83-E490 HydrophobicContact CE-CG 4.26Å; M83-E490 HydrophobicContact CG-CB 4.26Å
84	I	95.3	Very high	97.2	Very high	0 Å²	0	24.7 Å²	24.7	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-101.9	-1.1	172.5	74.2	-178.8	0	0	0	113.2	V80 P81 L82 A86 T164 K169 P170 V182	V80-I84 HydrophobicContact CG1-CD1 4.41Å; V80-I84 WeakPolarHBondContact O-CG1 3.23Å; V80-I84 PolarHBondContact O-N 3.14Å; V80-I84 VanDerWaalsContact O-N 3.12Å; P81-I84 PolarHBondContact O-N 3.35Å; L82-I84 VanDerWaalsContact C-N 3.3Å; L82-I84 PolarHBondContact O-N 3.06Å; I84-A86 HydrophobicContact CD1-CB 3.92Å; I84-A86 HydrophobicContact CG1-CB 3.71Å; I84-T164 HydrophobicContact CD1-CG2 3.97Å; I84-K169 HydrophobicContact CB-CG 4.07Å; I84-K169 HydrophobicContact CD1-CG 4.32Å; I84-K169 HydrophobicContact CG2-CG 4.33Å; I84-P170 WeakPolarHBondContact O-CD 3.43Å; I84-V182 HydrophobicContact CG2-CB 4.45Å; I84-V182 HydrophobicContact CG2-CG1 3.77Å; I84-V182 HydrophobicContact CG2-CG2 3.92Å
85	G	93.9	Very high	97.2	Very high	5 Å²	5	24.7 Å²	24.7	5%	0.052	12%	0.122	C	C	.	.	T	Hydrogen-bonded Turn	trans	69.4	29	-178	0	0	0	0	0	114.3	P81 L82 F502	P81-G85 PolarHBondContact O-N 3.33Å; L82-G85 PolarHBondContact O-N 3.39Å; G85-F502 WeakPolarHBondContact O-CB 3.39Å
86	A	94.9	Very high	97.2	Very high	0 Å²	0	25.8 Å²	25.8	0%	0	13%	0.127	C	C	.	.			trans	-91.5	143.8	175.7	0	0	0	0	0	111.2	P81 I84 D88 M168 F502	P81-A86 HydrophobicContact CB-CB 4.29Å; P81-A86 PolarHBondContact O-N 3.3Å; I84-A86 HydrophobicContact CD1-CB 3.92Å; I84-A86 HydrophobicContact CG1-CB 3.71Å; A86-D88 PolarHBondContact O-N 3.34Å; A86-M168 HydrophobicContact CB-CB 4.03Å; A86-M168 HydrophobicContact CB-CE 4.49Å; A86-F502 WeakPolarHBondContact O-CD2 3.5Å
87	P	94.6	Very high	97.2	Very high	59 Å²	59	30.7 Å²	30.7	38%	0.383	15%	0.152	S	C	.	.	S	Bend	trans	-71	-29	-179.7	26.9	-34.7	0	0	0	113.9	T501	P87-T501 VanDerWaalsContact CA-O 3.26Å; P87-T501 WeakPolarHBondContact CA-O 3.26Å; P87-T501 WeakPolarHBondContact CB-O 3.49Å
88	D	96.3	Very high	97.2	Very high	24 Å²	24	30.7 Å²	30.7	13%	0.128	15%	0.151	C	C	.	.	S	Bend	trans	-161.3	-175.6	175.9	-148.6	-26	0	0	0	109.9	T7 H9 A86 M168	T7-D88 VanDerWaalsContact O-OD2 3.11Å; H9-D88 VanDerWaalsContact CB-OD1 3.28Å; H9-D88 WeakPolarHBondContact CB-OD1 3.22Å; H9-D88 IonicContact CD2-OD1 3.12Å; H9-D88 PolarHBondContact CD2-OD1 3.45Å; H9-D88 VanDerWaalsContact CD2-OD1 3.31Å; H9-D88 IonicContact CG-OD1 2.6Å; H9-D88 PolarHBondContact N-OD1 3.4Å; A86-D88 PolarHBondContact O-N 3.34Å; D88-M168 WeakPolarHBondContact O-CE 3.48Å
89	M	97.4	Very high	97.2	Very high	3 Å²	3	30.5 Å²	30.5	2%	0.015	15%	0.151	C	C	.	.			trans	-75.8	157.3	170.1	-62.1	-71.8	-70.6	0	0	112.1	H9 P81 F91 P92 N160 F161 T164	H9-M89 HydrophobicContact CB-CG 3.79Å; P81-M89 HydrophobicContact CG-CG 3.96Å; P81-M89 HydrophobicContact CG-SD 3.47Å; P81-M89 WeakPolarHBondContact CG-SD 3.3Å; M89-F91 PolarHBondContact O-N 2.85Å; M89-P92 WeakPolarHBondContact O-CD 3.44Å; M89-P92 WeakPolarHBondContact O-CG 3.34Å; M89-N160 HydrophobicContact CE-CB 4.33Å; M89-N160 WeakPolarHBondContact CE-ND2 3.23Å; M89-F161 HydrophobicContact CE-CD1 3.47Å; M89-F161 VanDerWaalsContact CE-CD1 3.47Å; M89-F161 HydrophobicContact CE-CE1 3.56Å; M89-F161 HydrophobicContact CE-CG 4.04Å; M89-F161 HydrophobicContact CE-CZ 4.22Å; M89-F161 HydrophobicContact SD-CD1 4.39Å; M89-F161 HydrophobicContact SD-CE1 4.2Å; M89-T164 HydrophobicContact SD-CG2 3.86Å
90	A	98.1	Very high	97.2	Very high	31 Å²	31	35 Å²	35	26%	0.256	17%	0.168	S	C	.	.	S	Bend	trans	-64.6	-36.7	-177.3	0	0	0	0	0	113.5	P92 N160 T163 T164 M168	A90-P92 VanDerWaalsContact C-CD 3.49Å; A90-P92 WeakPolarHBondContact O-CD 3.47Å; A90-N160 PolarHBondContact N-OD1 3.25Å; A90-T163 HydrophobicContact CB-CG2 3.73Å; A90-T164 WeakPolarHBondContact CB-OG1 3.27Å; A90-T164 PolarHBondContact N-OG1 3.4Å; A90-M168 WeakPolarHBondContact CA-SD 3.3Å; A90-M168 HydrophobicContact CB-CG 4.43Å; A90-M168 HydrophobicContact CB-SD 3.61Å; A90-M168 PolarHBondContact N-SD 2.94Å
91	F	98.5	Very high	97.2	Very high	81 Å²	81	36.4 Å²	36.4	36%	0.355	18%	0.175	S	C	.	.			trans	-122.9	74.9	179.4	-52	-52.9	0	0	0	111.6	M89 R93 M94 N95 I159 N160 T163	M89-F91 PolarHBondContact O-N 2.85Å; F91-R93 VanDerWaalsContact C-N 3.32Å; F91-R93 PolarHBondContact O-N 3.42Å; F91-M94 HydrophobicContact CB-CB 3.67Å; F91-M94 HydrophobicContact CB-SD 4.3Å; F91-M94 HydrophobicContact CD2-CE 4.28Å; F91-M94 HydrophobicContact CD2-SD 4.12Å; F91-M94 HydrophobicContact CG-CE 4.44Å; F91-M94 WeakPolarHBondContact O-CB 3.29Å; F91-M94 PolarHBondContact O-N 3.05Å; F91-M94 VanDerWaalsContact O-N 3.12Å; F91-N95 PolarHBondContact O-N 3.14Å; F91-I159 HydrophobicContact CE2-CG2 4.15Å; F91-N160 HydrophobicContact CD2-CB 4.3Å; F91-N160 PolarHBondContact N-OD1 3.45Å; F91-T163 HydrophobicContact CE2-CG2 3.8Å; F91-T163 WeakPolarHBondContact CE2-OG1 3.33Å; F91-T163 HydrophobicContact CZ-CG2 3.77Å
92	P	97.9	Very high	97.3	Very high	36 Å²	36	36.6 Å²	36.6	23%	0.234	18%	0.176	C	C	.	.	H	α-helix	trans	-57.1	-38.1	-173.8	-29.3	37.6	0	0	0	115	T7 M89 A90 N95 N96	T7-P92 HydrophobicContact CG2-CB 4.23Å; T7-P92 WeakPolarHBondContact O-CB 3.4Å; M89-P92 WeakPolarHBondContact O-CD 3.44Å; M89-P92 WeakPolarHBondContact O-CG 3.34Å; A90-P92 VanDerWaalsContact C-CD 3.49Å; A90-P92 WeakPolarHBondContact O-CD 3.47Å; P92-N95 VanDerWaalsContact O-CB 3.29Å; P92-N95 WeakPolarHBondContact O-CB 3.37Å; P92-N95 PolarHBondContact O-N 3.39Å; P92-N96 PolarHBondContact O-N 3.04Å; P92-N96 VanDerWaalsContact O-N 3.09Å
93	R	98.4	Very high	97.4	Very high	206 Å²	206	38.1 Å²	38.1	78%	0.777	19%	0.186	S	C	*	.	H	α-helix	trans	-74.3	-36.2	178.6	-65.2	-179.5	-175.4	171.7	1.6	112.7	T7 F91 N95 N96 M97	T7-R93 HydrophobicContact CG2-CG 4.05Å; F91-R93 VanDerWaalsContact C-N 3.32Å; F91-R93 PolarHBondContact O-N 3.42Å; R93-N95 PolarHBondContact O-N 3.15Å; R93-N96 PolarHBondContact O-N 3.38Å; R93-M97 PolarHBondContact O-N 3.23Å
94	M	97.9	Very high	97.6	Very high	57 Å²	57	40.6 Å²	40.6	28%	0.281	20%	0.203	S	C	.	.	H	α-helix	trans	-64.2	-37.2	173.4	-175.6	-176.2	-67.7	0	0	110.1	F91 M97 S98 L156 I159	F91-M94 HydrophobicContact CB-CB 3.67Å; F91-M94 HydrophobicContact CB-SD 4.3Å; F91-M94 HydrophobicContact CD2-CE 4.28Å; F91-M94 HydrophobicContact CD2-SD 4.12Å; F91-M94 HydrophobicContact CG-CE 4.44Å; F91-M94 WeakPolarHBondContact O-CB 3.29Å; F91-M94 PolarHBondContact O-N 3.05Å; F91-M94 VanDerWaalsContact O-N 3.12Å; M94-M97 PolarHBondContact O-N 3.08Å; M94-S98 PolarHBondContact O-N 2.91Å; M94-S98 PolarHBondContact O-OG 3.46Å; M94-L156 HydrophobicContact CE-CD2 4.42Å; M94-L156 HydrophobicContact CG-CB 3.87Å; M94-L156 HydrophobicContact CG-CD2 3.95Å; M94-L156 HydrophobicContact CG-CG 4.34Å; M94-L156 HydrophobicContact SD-CB 4.29Å; M94-L156 HydrophobicContact SD-CD2 4.01Å; M94-I159 HydrophobicContact SD-CG2 4.41Å
95	N	98.4	Very high	97.7	Very high	0 Å²	0	40.6 Å²	40.6	0%	0	20%	0.203	C	C	.	.	H	α-helix	trans	-62.8	-40.7	173.3	-157.1	35.5	0	0	0	113.3	I12 N77 F91 P92 R93 S98 F99 N160	I12-N95 HydrophobicContact CD1-CB 4.07Å; N77-N95 PolarHBondContact OD1-ND2 3.37Å; N77-N95 PolarHBondContact OD1-OD1 3.49Å; F91-N95 PolarHBondContact O-N 3.14Å; P92-N95 VanDerWaalsContact O-CB 3.29Å; P92-N95 WeakPolarHBondContact O-CB 3.37Å; P92-N95 PolarHBondContact O-N 3.39Å; R93-N95 PolarHBondContact O-N 3.15Å; N95-S98 WeakPolarHBondContact CA-OG 3.32Å; N95-S98 PolarHBondContact O-OG 2.92Å; N95-F99 PolarHBondContact O-N 3.47Å; N95-N160 WeakPolarHBondContact CB-ND2 3.38Å
96	N	98.6	Very high	98	Very high	23 Å²	23	40.6 Å²	40.6	12%	0.123	20%	0.201	C	C	.	.	H	α-helix	trans	-66.4	-44.2	175	-171	42.2	0	0	0	110.5	L4 S6 I12 P92 R93 S98 F99 W100	L4-N96 PolarHBondContact O-ND2 3.31Å; S6-N96 VanDerWaalsContact O-CB 3.28Å; S6-N96 WeakPolarHBondContact O-CB 3.21Å; S6-N96 VanDerWaalsContact O-CG 3.23Å; I12-N96 HydrophobicContact CD1-CB 3.92Å; P92-N96 PolarHBondContact O-N 3.04Å; P92-N96 VanDerWaalsContact O-N 3.09Å; R93-N96 PolarHBondContact O-N 3.38Å; N96-S98 VanDerWaalsContact C-N 3.35Å; N96-S98 PolarHBondContact O-N 2.77Å; N96-F99 PolarHBondContact O-N 2.75Å; N96-W100 PolarHBondContact O-N 2.97Å; N96-W100 VanDerWaalsContact O-N 3.07Å; N96-W100 PolarHBondContact OD1-NE1 3.13Å
97	M	98.1	Very high	98.1	Very high	104 Å²	104	46.2 Å²	46.2	51%	0.512	23%	0.231	S	C	.	.	H	α-helix	trans	-61.5	-40.9	177.3	-175.7	175.4	178.1	0	0	112.1	R93 M94 F99 W100 L101 L156	R93-M97 PolarHBondContact O-N 3.23Å; M94-M97 PolarHBondContact O-N 3.08Å; M97-F99 VanDerWaalsContact C-N 3.29Å; M97-F99 PolarHBondContact O-N 3.44Å; M97-W100 PolarHBondContact O-N 3.2Å; M97-L101 HydrophobicContact CE-CD1 4.47Å; M97-L101 HydrophobicContact CG-CD1 4.41Å; M97-L101 WeakPolarHBondContact O-CG 3.25Å; M97-L101 PolarHBondContact O-N 2.9Å; M97-L156 HydrophobicContact CG-CD1 4.24Å; M97-L156 HydrophobicContact SD-CD1 4.24Å
98	S	98.4	Very high	98.3	Very high	0 Å²	0	45.6 Å²	45.6	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-58.8	-42.1	176.6	60.1	0	0	0	0	111.2	Y16 M94 N95 N96 S153	Y16-S98 WeakPolarHBondContact OH-CB 3.43Å; Y16-S98 PolarHBondContact OH-OG 3.28Å; M94-S98 PolarHBondContact O-N 2.91Å; M94-S98 PolarHBondContact O-OG 3.46Å; N95-S98 WeakPolarHBondContact CA-OG 3.32Å; N95-S98 PolarHBondContact O-OG 2.92Å; N96-S98 VanDerWaalsContact C-N 3.35Å; N96-S98 PolarHBondContact O-N 2.77Å; S98-S153 VanDerWaalsContact CB-O 3.28Å; S98-S153 WeakPolarHBondContact CB-O 3.24Å; S98-S153 WeakPolarHBondContact O-CB 3.48Å; S98-S153 PolarHBondContact O-OG 3.47Å
99	F	98.8	Very high	98.4	Very high	9 Å²	9	44.7 Å²	44.7	4%	0.039	22%	0.219	C	C	.	.	H	α-helix	trans	-63	-50.7	175.3	171.4	-101.6	0	0	0	112	I12 L15 Y16 F19 N95 N96 M97 L101 L102 P103	I12-F99 HydrophobicContact CG2-CB 4.14Å; L15-F99 VanDerWaalsContact C-CE2 3.44Å; L15-F99 HydrophobicContact CB-CD1 4.09Å; L15-F99 HydrophobicContact CB-CD2 3.99Å; L15-F99 HydrophobicContact CB-CE1 3.77Å; L15-F99 HydrophobicContact CB-CE2 3.66Å; L15-F99 HydrophobicContact CB-CG 4.21Å; L15-F99 HydrophobicContact CB-CZ 3.56Å; L15-F99 HydrophobicContact CD1-CD1 3.94Å; L15-F99 HydrophobicContact CD1-CE1 3.82Å; L15-F99 HydrophobicContact CD1-CZ 4.45Å; L15-F99 HydrophobicContact CD2-CE1 4.47Å; L15-F99 HydrophobicContact CD2-CZ 4.5Å; L15-F99 HydrophobicContact CG-CE1 4.24Å; L15-F99 HydrophobicContact CG-CZ 4.39Å; L15-F99 WeakPolarHBondContact O-CE2 3.4Å; Y16-F99 AromaticContact CD1-CD2 3.88Å; Y16-F99 HydrophobicContact CD1-CD2 3.88Å; Y16-F99 HydrophobicContact CD2-CB 4.28Å; Y16-F99 HydrophobicContact CD2-CD2 4.07Å; Y16-F99 HydrophobicContact CE1-CB 4.35Å; Y16-F99 HydrophobicContact CE1-CD2 4.07Å; Y16-F99 HydrophobicContact CE2-CB 3.69Å; Y16-F99 HydrophobicContact CE2-CD2 4.23Å; Y16-F99 HydrophobicContact CE2-CG 4.42Å; Y16-F99 AromaticContact CG-CD2 3.88Å; Y16-F99 HydrophobicContact CG-CD2 3.88Å; Y16-F99 WeakPolarHBondContact OH-CA 3.37Å; Y16-F99 PolarHBondContact OH-N 3.46Å; F19-F99 HydrophobicContact CB-CE2 3.89Å; F19-F99 HydrophobicContact CB-CZ 4.42Å; F19-F99 HydrophobicContact CG-CE2 4.38Å; N95-F99 PolarHBondContact O-N 3.47Å; N96-F99 PolarHBondContact O-N 2.75Å; M97-F99 VanDerWaalsContact C-N 3.29Å; M97-F99 PolarHBondContact O-N 3.44Å; F99-L101 PolarHBondContact O-N 2.83Å; F99-L101 VanDerWaalsContact O-N 3.1Å; F99-L102 WeakPolarHBondContact O-CB 3.27Å; F99-L102 PolarHBondContact O-N 3.28Å; F99-P103 HydrophobicContact CZ-CG 4.39Å; F99-P103 WeakPolarHBondContact O-CD 3.43Å
100	W	98.6	Very high	98.5	Very high	95 Å²	95	46.5 Å²	46.5	36%	0.36	23%	0.228	S	C	.	.	H	α-helix	trans	-68.6	-11.3	-172.2	-77.5	110.7	0	0	0	114.9	L4 L15 N96 M97 P103 P104	L4-W100 HydrophobicContact CD1-CD2 4.34Å; L4-W100 HydrophobicContact CD1-CH2 3.74Å; L4-W100 HydrophobicContact CD1-CZ2 3.5Å; L4-W100 VanDerWaalsContact CD1-CZ2 3.5Å; L4-W100 HydrophobicContact CD1-CZ3 4.26Å; L4-W100 PolarHBondContact O-NE1 3.26Å; L15-W100 HydrophobicContact CD1-CZ2 4.5Å; N96-W100 PolarHBondContact O-N 2.97Å; N96-W100 VanDerWaalsContact O-N 3.07Å; N96-W100 PolarHBondContact OD1-NE1 3.13Å; M97-W100 PolarHBondContact O-N 3.2Å; W100-P103 HydrophobicContact CE3-CG 4.39Å; W100-P104 WeakPolarHBondContact O-CD 3.29Å; W100-P104 WeakPolarHBondContact O-CG 3.19Å
101	L	98.7	Very high	98.5	Very high	29 Å²	29	46.4 Å²	46.4	15%	0.152	23%	0.228	C	C	.	.	T	Hydrogen-bonded Turn	trans	-77.2	-21.5	170.2	-70.2	171.1	0	0	0	113.1	M97 F99 P104 S105 L149 V152 L156	M97-L101 HydrophobicContact CE-CD1 4.47Å; M97-L101 HydrophobicContact CG-CD1 4.41Å; M97-L101 WeakPolarHBondContact O-CG 3.25Å; M97-L101 PolarHBondContact O-N 2.9Å; F99-L101 PolarHBondContact O-N 2.83Å; F99-L101 VanDerWaalsContact O-N 3.1Å; L101-P104 WeakPolarHBondContact O-CD 3.25Å; L101-P104 WeakPolarHBondContact O-CG 3.45Å; L101-S105 WeakPolarHBondContact O-CB 3.2Å; L101-S105 PolarHBondContact O-N 2.83Å; L101-L149 HydrophobicContact CD2-CD2 4.3Å; L101-V152 HydrophobicContact CD1-CB 4.21Å; L101-V152 HydrophobicContact CD1-CG1 3.68Å; L101-L156 HydrophobicContact CD1-CD1 4.1Å
102	L	98.8	Very high	98.4	Very high	4 Å²	4	42.7 Å²	42.7	2%	0.021	21%	0.212	C	C	.	.	H	α-helix	trans	-73	-44.1	-178.2	-66.9	-177.3	0	0	0	114.4	Y16 F19 P69 F99 S105 L106 A150	Y16-L102 HydrophobicContact CD1-CD1 3.88Å; Y16-L102 HydrophobicContact CE1-CD1 3.45Å; Y16-L102 VanDerWaalsContact CE1-CD1 3.45Å; F19-L102 HydrophobicContact CD1-CB 4.44Å; F19-L102 HydrophobicContact CD1-CD1 4.24Å; F19-L102 HydrophobicContact CE1-CB 3.84Å; F19-L102 HydrophobicContact CE1-CD1 4.04Å; F19-L102 HydrophobicContact CE2-CB 4.43Å; F19-L102 HydrophobicContact CZ-CB 3.81Å; P69-L102 HydrophobicContact CB-CD1 4.09Å; P69-L102 HydrophobicContact CG-CD1 3.71Å; F99-L102 WeakPolarHBondContact O-CB 3.27Å; F99-L102 PolarHBondContact O-N 3.28Å; L102-S105 WeakPolarHBondContact O-CB 3.49Å; L102-S105 PolarHBondContact O-N 3.44Å; L102-L106 PolarHBondContact O-N 3.05Å; L102-A150 HydrophobicContact CD2-CB 4.33Å
103	P	98.7	Very high	98.3	Very high	33 Å²	33	42.8 Å²	42.8	21%	0.214	22%	0.216	C	C	.	.	H	α-helix	trans	-56.1	-50.2	175.5	-25.2	33.9	0	0	0	114.6	F19 F99 W100 S105 L106 L107	F19-P103 HydrophobicContact CD2-CG 4.31Å; F19-P103 HydrophobicContact CE2-CB 4.45Å; F19-P103 HydrophobicContact CE2-CG 4.22Å; F99-P103 HydrophobicContact CZ-CG 4.39Å; F99-P103 WeakPolarHBondContact O-CD 3.43Å; W100-P103 HydrophobicContact CE3-CG 4.39Å; P103-S105 VanDerWaalsContact C-N 3.3Å; P103-S105 PolarHBondContact O-N 3.38Å; P103-L106 PolarHBondContact O-N 3.28Å; P103-L107 WeakPolarHBondContact O-CG 3.28Å; P103-L107 PolarHBondContact O-N 3.48Å
104	P	98.7	Very high	98.1	Very high	54 Å²	54	40.1 Å²	40.1	35%	0.351	21%	0.214	S	C	.	.	H	α-helix	trans	-65.8	-33.3	176.5	25.3	-32.5	0	0	0	112.4	W100 L101 L107 L108 L149	W100-P104 WeakPolarHBondContact O-CD 3.29Å; W100-P104 WeakPolarHBondContact O-CG 3.19Å; L101-P104 WeakPolarHBondContact O-CD 3.25Å; L101-P104 WeakPolarHBondContact O-CG 3.45Å; P104-L107 PolarHBondContact O-N 3.03Å; P104-L108 WeakPolarHBondContact O-CG 3.35Å; P104-L108 PolarHBondContact O-N 2.72Å; P104-L149 HydrophobicContact CB-CD1 4.41Å
105	S	98.8	Very high	97.9	Very high	0 Å²	0	39.8 Å²	39.8	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-59.9	-48.5	172.8	174.5	0	0	0	0	111.7	F65 L101 L102 P103 L107 L108 L109 S146 A150	F65-S105 VanDerWaalsContact CE1-OG 3.28Å; F65-S105 WeakPolarHBondContact CE1-OG 3.47Å; F65-S105 WeakPolarHBondContact CZ-OG 3.26Å; L101-S105 WeakPolarHBondContact O-CB 3.2Å; L101-S105 PolarHBondContact O-N 2.83Å; L102-S105 WeakPolarHBondContact O-CB 3.49Å; L102-S105 PolarHBondContact O-N 3.44Å; P103-S105 VanDerWaalsContact C-N 3.3Å; P103-S105 PolarHBondContact O-N 3.38Å; S105-L107 VanDerWaalsContact C-N 3.34Å; S105-L107 PolarHBondContact O-N 3.2Å; S105-L108 WeakPolarHBondContact O-CB 3.41Å; S105-L108 PolarHBondContact O-N 3.41Å; S105-L109 PolarHBondContact O-N 2.84Å; S105-S146 VanDerWaalsContact O-CB 3.32Å; S105-S146 WeakPolarHBondContact O-CB 3.39Å; S105-S146 PolarHBondContact O-OG 3.4Å; S105-S146 VanDerWaalsContact O-OG 3.07Å; S105-S146 PolarHBondContact OG-O 2.92Å; S105-S146 PolarHBondContact OG-OG 3.15Å; S105-A150 PolarHBondContact OG-N 2.88Å
106	L	98.8	Very high	97.7	Very high	5 Å²	5	45.4 Å²	45.4	3%	0.026	24%	0.241	C	C	.	.	H	α-helix	trans	-63.6	-40.2	176.7	-178.1	54.9	0	0	0	111.8	F19 W22 A23 V61 F65 L102 P103 L108 L109 L110	F19-L106 HydrophobicContact CE2-CB 4.26Å; F19-L106 HydrophobicContact CE2-CD2 3.69Å; F19-L106 HydrophobicContact CZ-CB 3.93Å; F19-L106 HydrophobicContact CZ-CD2 3.62Å; F19-L106 HydrophobicContact CZ-CG 4.43Å; W22-L106 HydrophobicContact CE3-CD2 4.02Å; W22-L106 HydrophobicContact CZ3-CD2 3.64Å; A23-L106 HydrophobicContact CB-CD2 4.31Å; V61-L106 HydrophobicContact CG2-CD1 4.23Å; F65-L106 HydrophobicContact CB-CD1 4.25Å; F65-L106 HydrophobicContact CD1-CB 3.74Å; F65-L106 HydrophobicContact CD1-CD1 4.11Å; F65-L106 HydrophobicContact CD1-CG 4.34Å; F65-L106 HydrophobicContact CD2-CD1 4.08Å; F65-L106 HydrophobicContact CE1-CB 3.72Å; F65-L106 HydrophobicContact CE1-CD1 4.46Å; F65-L106 HydrophobicContact CE2-CD1 4.46Å; F65-L106 HydrophobicContact CG-CB 4.38Å; F65-L106 HydrophobicContact CG-CD1 3.86Å; F65-L106 HydrophobicContact CZ-CB 4.37Å; L102-L106 PolarHBondContact O-N 3.05Å; P103-L106 PolarHBondContact O-N 3.28Å; L106-L108 VanDerWaalsContact C-N 3.3Å; L106-L108 PolarHBondContact O-N 2.92Å; L106-L109 HydrophobicContact CD1-CD2 4.39Å; L106-L109 WeakPolarHBondContact O-CB 3.43Å; L106-L109 PolarHBondContact O-N 3.48Å; L106-L109 VanDerWaalsContact O-N 3.17Å; L106-L110 HydrophobicContact CD1-CD1 4.39Å; L106-L110 HydrophobicContact CD1-CD2 4.44Å; L106-L110 HydrophobicContact CD1-CG 4.18Å; L106-L110 HydrophobicContact CG-CD1 4.25Å; L106-L110 HydrophobicContact CG-CG 4.44Å; L106-L110 WeakPolarHBondContact O-CG 3.37Å; L106-L110 PolarHBondContact O-N 3.47Å
107	L	98.6	Very high	97.4	Very high	118 Å²	118	47.3 Å²	47.3	62%	0.618	26%	0.26	S	S	*	.	H	α-helix	trans	-61.2	-38.9	175.5	-70.5	174	0	0	0	112.1	P103 P104 S105 L110 A111	P103-L107 WeakPolarHBondContact O-CG 3.28Å; P103-L107 PolarHBondContact O-N 3.48Å; P104-L107 PolarHBondContact O-N 3.03Å; S105-L107 VanDerWaalsContact C-N 3.34Å; S105-L107 PolarHBondContact O-N 3.2Å; L107-L110 PolarHBondContact O-N 2.79Å; L107-A111 VanDerWaalsContact O-CB 3.23Å; L107-A111 WeakPolarHBondContact O-CB 3.47Å; L107-A111 PolarHBondContact O-N 3.23Å
108	L	98.7	Very high	97.4	Very high	46 Å²	46	42.3 Å²	42.3	24%	0.241	24%	0.236	C	C	.	.	H	α-helix	trans	-63.7	-41	173.7	-73.1	168	0	0	0	111.8	P104 S105 L106 A111 S112 L142 F145 L149	P104-L108 WeakPolarHBondContact O-CG 3.35Å; P104-L108 PolarHBondContact O-N 2.72Å; S105-L108 WeakPolarHBondContact O-CB 3.41Å; S105-L108 PolarHBondContact O-N 3.41Å; L106-L108 VanDerWaalsContact C-N 3.3Å; L106-L108 PolarHBondContact O-N 2.92Å; L108-A111 PolarHBondContact O-N 3.28Å; L108-S112 WeakPolarHBondContact O-CB 3.37Å; L108-S112 PolarHBondContact O-N 3.43Å; L108-L142 HydrophobicContact CD2-CD2 3.75Å; L108-F145 HydrophobicContact CD1-CB 4.06Å; L108-L149 HydrophobicContact CD1-CD1 3.65Å; L108-L149 HydrophobicContact CD1-CG 4.5Å
109	L	98.6	Very high	97.3	Very high	5 Å²	5	42.5 Å²	42.5	3%	0.026	24%	0.237	C	C	.	.	H	α-helix	trans	-63.2	-43.1	175.2	-176.7	67.1	0	0	0	111.9	F60 V61 F65 S105 L106 S112 A113 T143	F60-L109 HydrophobicContact CB-CD1 4.08Å; F60-L109 HydrophobicContact CB-CD2 3.63Å; F60-L109 HydrophobicContact CD2-CD1 3.92Å; F60-L109 HydrophobicContact CG-CD1 4.28Å; V61-L109 HydrophobicContact CG2-CD2 3.78Å; F65-L109 HydrophobicContact CD2-CD2 3.95Å; F65-L109 HydrophobicContact CE2-CB 4.46Å; F65-L109 HydrophobicContact CE2-CD2 3.61Å; S105-L109 PolarHBondContact O-N 2.84Å; L106-L109 HydrophobicContact CD1-CD2 4.39Å; L106-L109 WeakPolarHBondContact O-CB 3.43Å; L106-L109 PolarHBondContact O-N 3.48Å; L106-L109 VanDerWaalsContact O-N 3.17Å; L109-S112 VanDerWaalsContact O-CB 3.28Å; L109-S112 WeakPolarHBondContact O-CB 3.09Å; L109-S112 PolarHBondContact O-N 3.41Å; L109-A113 PolarHBondContact O-N 3.36Å; L109-T143 HydrophobicContact CD1-CG2 4.31Å
110	L	97.9	Very high	97.3	Very high	40 Å²	40	42.4 Å²	42.4	21%	0.209	24%	0.238	C	C	.	.	H	α-helix	trans	-71.1	-38.1	179.2	-61.1	179.9	0	0	0	111.6	W22 L26 L106 L107 S112 A113 M114	W22-L110 HydrophobicContact CH2-CD1 4.34Å; L26-L110 HydrophobicContact CD2-CD1 3.9Å; L26-L110 HydrophobicContact CD2-CD2 3.71Å; L26-L110 HydrophobicContact CD2-CG 4.41Å; L106-L110 HydrophobicContact CD1-CD1 4.39Å; L106-L110 HydrophobicContact CD1-CD2 4.44Å; L106-L110 HydrophobicContact CD1-CG 4.18Å; L106-L110 HydrophobicContact CG-CD1 4.25Å; L106-L110 HydrophobicContact CG-CG 4.44Å; L106-L110 WeakPolarHBondContact O-CG 3.37Å; L106-L110 PolarHBondContact O-N 3.47Å; L107-L110 PolarHBondContact O-N 2.79Å; L110-S112 VanDerWaalsContact C-N 3.29Å; L110-S112 PolarHBondContact O-N 3.34Å; L110-A113 PolarHBondContact O-N 2.99Å; L110-M114 WeakPolarHBondContact O-CE 3.34Å; L110-M114 WeakPolarHBondContact O-CG 3.17Å; L110-M114 PolarHBondContact O-N 3.43Å
111	A	98.1	Very high	97.2	Very high	30 Å²	30	38 Å²	38	25%	0.248	22%	0.222	C	C	.	.	H	α-helix	trans	-61	-41	171.3	0	0	0	0	0	111.2	L107 L108 A113 M114 V115 L142	L107-A111 VanDerWaalsContact O-CB 3.23Å; L107-A111 WeakPolarHBondContact O-CB 3.47Å; L107-A111 PolarHBondContact O-N 3.23Å; L108-A111 PolarHBondContact O-N 3.28Å; A111-A113 PolarHBondContact O-N 3.31Å; A111-M114 PolarHBondContact O-N 2.97Å; A111-V115 WeakPolarHBondContact O-CB 3.4Å; A111-V115 VanDerWaalsContact O-CG2 3.31Å; A111-V115 WeakPolarHBondContact O-CG2 3.36Å; A111-V115 PolarHBondContact O-N 3Å; A111-L142 HydrophobicContact CB-CD1 4.27Å
112	S	98	Very high	97.1	Very high	2 Å²	2	36.9 Å²	36.9	1%	0.014	22%	0.217	C	C	.	.	H	α-helix	trans	-54.8	-39.8	174.6	173	0	0	0	0	112.3	L108 L109 L110 M114 G118 S139 T143	L108-S112 WeakPolarHBondContact O-CB 3.37Å; L108-S112 PolarHBondContact O-N 3.43Å; L109-S112 VanDerWaalsContact O-CB 3.28Å; L109-S112 WeakPolarHBondContact O-CB 3.09Å; L109-S112 PolarHBondContact O-N 3.41Å; L110-S112 VanDerWaalsContact C-N 3.29Å; L110-S112 PolarHBondContact O-N 3.34Å; S112-M114 VanDerWaalsContact C-N 3.3Å; S112-M114 PolarHBondContact O-N 3.1Å; S112-G118 VanDerWaalsContact O-CA 3.28Å; S112-G118 WeakPolarHBondContact O-CA 3.46Å; S112-S139 WeakPolarHBondContact CB-O 3.29Å; S112-S139 PolarHBondContact OG-O 3.42Å; S112-T143 PolarHBondContact OG-OG1 2.88Å
113	A	94.5	Very high	97	Very high	39 Å²	39	38.2 Å²	38.2	32%	0.322	22%	0.222	S	C	.	.	H	α-helix	trans	-73.1	-19.2	177.9	0	0	0	0	0	114.2	V53 L109 L110 A111	V53-A113 HydrophobicContact CG1-CB 3.87Å; L109-A113 PolarHBondContact O-N 3.36Å; L110-A113 PolarHBondContact O-N 2.99Å; A111-A113 PolarHBondContact O-N 3.31Å
114	M	94.1	Very high	97	Very high	150 Å²	150	36.7 Å²	36.7	74%	0.739	21%	0.212	S	C	*	.	H	α-helix	trans	-101.8	-21.1	-177.8	-65.2	-174.5	-68.8	0	0	113.8	L110 A111 S112	L110-M114 WeakPolarHBondContact O-CE 3.34Å; L110-M114 WeakPolarHBondContact O-CG 3.17Å; L110-M114 PolarHBondContact O-N 3.43Å; A111-M114 PolarHBondContact O-N 2.97Å; S112-M114 VanDerWaalsContact C-N 3.3Å; S112-M114 PolarHBondContact O-N 3.1Å
115	V	95.4	Very high	96.9	Very high	50 Å²	50	34.2 Å²	34.2	30%	0.303	20%	0.196	S	C	.	.	S	Bend	trans	-83.6	131.6	-179.4	170.1	0	0	0	0	109.9	A111 A117 G118 A138 L142	A111-V115 WeakPolarHBondContact O-CB 3.4Å; A111-V115 VanDerWaalsContact O-CG2 3.31Å; A111-V115 WeakPolarHBondContact O-CG2 3.36Å; A111-V115 PolarHBondContact O-N 3Å; V115-A117 PolarHBondContact O-N 2.74Å; V115-G118 PolarHBondContact O-N 2.73Å; V115-A138 HydrophobicContact CG1-CB 4.39Å; V115-L142 HydrophobicContact CB-CD1 4.18Å; V115-L142 HydrophobicContact CG2-CD1 3.95Å
116	E	93.3	Very high	96.9	Very high	118 Å²	118	36.4 Å²	36.4	55%	0.551	20%	0.204	S	C	*	.	T	Hydrogen-bonded Turn	trans	54.6	-121.1	-178.9	-59.7	155.5	171.2	0	0	111.3	G137 A138 S139	E116-G137 VanDerWaalsContact CD-CA 3.47Å; E116-G137 WeakPolarHBondContact OE1-CA 3.34Å; E116-G137 WeakPolarHBondContact OE2-CA 3.41Å; E116-A138 VanDerWaalsContact CD-N 3.27Å; E116-A138 PolarHBondContact OE1-N 2.91Å; E116-A138 PolarHBondContact OE2-N 2.94Å; E116-S139 PolarHBondContact OE2-N 3.4Å
117	A	92.9	Very high	96.8	Very high	62 Å²	62	36.8 Å²	36.8	51%	0.512	21%	0.207	S	C	.	.	T	Hydrogen-bonded Turn	trans	-95.5	-8.9	176.5	0	0	0	0	0	112.8	H49 V53 V115	H49-A117 PolarHBondContact CD2-O 2.78Å; H49-A117 WeakPolarHBondContact NE2-CB 3.24Å; H49-A117 PolarHBondContact NE2-O 2.82Å; V53-A117 WeakPolarHBondContact CG2-O 3.38Å; V115-A117 PolarHBondContact O-N 2.74Å
118	G	96.8	Very high	96.7	Very high	0 Å²	0	35.2 Å²	35.2	0%	0	20%	0.204	C	C	.	.			trans	79.5	162.9	-172.7	0	0	0	0	0	115.2	H49 S112 V115 G120	H49-G118 PolarHBondContact NE2-O 3.45Å; H49-G118 VanDerWaalsContact NE2-O 3.12Å; S112-G118 VanDerWaalsContact O-CA 3.28Å; S112-G118 WeakPolarHBondContact O-CA 3.46Å; V115-G118 PolarHBondContact O-N 2.73Å; G118-G120 PolarHBondContact O-N 3.34Å
119	A	97.6	Very high	96.7	Very high	4 Å²	4	36.9 Å²	36.9	3%	0.033	21%	0.213	C	C	.	.			trans	-81	94.8	179.9	0	0	0	0	0	112	T56 V140 T143	T56-A119 WeakPolarHBondContact CB-O 3.37Å; T56-A119 WeakPolarHBondContact CG2-O 3.45Å; T56-A119 PolarHBondContact OG1-O 3.31Å; A119-V140 HydrophobicContact CB-CG2 4.27Å; A119-T143 WeakPolarHBondContact CB-OG1 3.34Å
120	G	97.2	Very high	96.7	Very high	6 Å²	6	36.6 Å²	36.6	6%	0.062	21%	0.211	C	C	.	.			trans	-95.5	30.9	179	0	0	0	0	0	114	G118 H135	G118-G120 PolarHBondContact O-N 3.34Å; G120-H135 WeakPolarHBondContact CA-NE2 3.34Å; G120-H135 PolarHBondContact N-NE2 3.48Å; G120-H135 VanDerWaalsContact N-NE2 3.16Å
121	T	97.3	Very high	96.6	Very high	4 Å²	4	35.5 Å²	35.5	3%	0.025	21%	0.209	C	C	.	.	S	Bend	trans	-89.6	-6.2	-169.8	56.9	0	0	0	0	114	L129 A130 V140	T121-L129 HydrophobicContact CG2-CG 4.45Å; T121-A130 HydrophobicContact CG2-CB 3.82Å; T121-V140 HydrophobicContact CG2-CG2 4.08Å
122	G	96.9	Very high	96.4	Very high	4 Å²	4	37.2 Å²	37.2	4%	0.041	21%	0.214	C	C	.	.	T	Hydrogen-bonded Turn	trans	76	159.9	-163.5	0	0	0	0	0	111.7	T56 T124 V125	T56-G122 WeakPolarHBondContact OG1-CA 3.43Å; T56-G122 PolarHBondContact OG1-N 2.83Å; G122-T124 PolarHBondContact O-N 3.03Å; G122-V125 PolarHBondContact O-N 3.21Å
123	W	97.2	Very high	96.1	Very high	33 Å²	33	47.9 Å²	47.9	13%	0.125	26%	0.256	C	S	.	.	T	Hydrogen-bonded Turn	trans	-62.9	-14.9	-176.3	82.6	-81.5	0	0	0	114.7	A59 F60 I63 F232 W233	A59-W123 HydrophobicContact CB-CB 3.56Å; A59-W123 HydrophobicContact CB-CG 4.03Å; F60-W123 HydrophobicContact CD1-CB 4.49Å; F60-W123 HydrophobicContact CE1-CB 4.18Å; F60-W123 WeakPolarHBondContact CE1-O 3.45Å; F60-W123 HydrophobicContact CE2-CB 4.49Å; F60-W123 HydrophobicContact CZ-CB 4.19Å; F60-W123 WeakPolarHBondContact CZ-O 3.32Å; I63-W123 HydrophobicContact CD1-CE3 4.18Å; I63-W123 HydrophobicContact CD1-CZ3 4.24Å; W123-F232 HydrophobicContact CD2-CZ 4.32Å; W123-F232 HydrophobicContact CE3-CE1 4.48Å; W123-F232 AromaticContact CE3-CZ 3.74Å; W123-F232 HydrophobicContact CE3-CZ 3.74Å; W123-F232 AromaticContact CH2-CE1 3.92Å; W123-F232 HydrophobicContact CH2-CE1 3.92Å; W123-F232 AromaticContact CH2-CZ 3.92Å; W123-F232 HydrophobicContact CH2-CZ 3.92Å; W123-F232 HydrophobicContact CZ2-CE1 4.3Å; W123-F232 HydrophobicContact CZ2-CZ 4.47Å; W123-F232 HydrophobicContact CZ3-CE1 4.03Å; W123-F232 AromaticContact CZ3-CZ 3.53Å; W123-F232 HydrophobicContact CZ3-CZ 3.53Å; W123-W233 HydrophobicContact CH2-CH2 4.38Å; W123-W233 HydrophobicContact CH2-CZ3 4.08Å; W123-W233 AromaticContact CZ2-CH2 3.78Å; W123-W233 HydrophobicContact CZ2-CH2 3.78Å; W123-W233 AromaticContact CZ2-CZ3 3.92Å; W123-W233 HydrophobicContact CZ2-CZ3 3.92Å
124	T	97.1	Very high	96.1	Very high	0 Å²	0	48.6 Å²	48.6	0%	0	26%	0.259	C	S	.	.	T	Hydrogen-bonded Turn	trans	-82	-20.8	176.5	57.9	0	0	0	0	112.8	G122 Y126 Y228 F232 W233	G122-T124 PolarHBondContact O-N 3.03Å; T124-Y126 VanDerWaalsContact C-N 3.34Å; T124-Y126 HydrophobicContact CG2-CE1 4.28Å; T124-Y126 PolarHBondContact O-N 3.35Å; T124-Y228 WeakPolarHBondContact O-CE1 3.47Å; T124-Y228 PolarHBondContact O-OH 2.7Å; T124-F232 HydrophobicContact CG2-CD1 4.32Å; T124-F232 HydrophobicContact CG2-CE1 3.68Å; T124-F232 HydrophobicContact CG2-CZ 4.03Å; T124-W233 HydrophobicContact CG2-CH2 4.17Å; T124-W233 HydrophobicContact CG2-CZ2 3.99Å
125	V	97.9	Very high	96.3	Very high	2 Å²	2	42 Å²	42	1%	0.012	23%	0.226	C	C	.	.	T	Hydrogen-bonded Turn	trans	55.2	45.3	175.1	-159.7	0	0	0	0	112.5	F60 G122 A130 V140 L206 Y228	F60-V125 HydrophobicContact CE2-CG2 4.2Å; F60-V125 HydrophobicContact CZ-CG2 3.63Å; G122-V125 PolarHBondContact O-N 3.21Å; V125-A130 HydrophobicContact CG1-CB 3.63Å; V125-A130 WeakPolarHBondContact O-CB 3.37Å; V125-V140 HydrophobicContact CG1-CG1 4.1Å; V125-L206 HydrophobicContact CG1-CD2 3.84Å; V125-Y228 PolarHBondContact O-OH 3.47Å
126	Y	98.2	Very high	96.1	Very high	46 Å²	46	44 Å²	44	18%	0.18	24%	0.24	C	C	.	.			trans	-70.3	130.7	-175.1	-69.8	-23.7	0	0	0	113.2	T124 L129 A130 Y228 Q229 F232 W233	T124-Y126 VanDerWaalsContact C-N 3.34Å; T124-Y126 HydrophobicContact CG2-CE1 4.28Å; T124-Y126 PolarHBondContact O-N 3.35Å; Y126-L129 WeakPolarHBondContact O-CB 3.37Å; Y126-L129 PolarHBondContact O-N 3.07Å; Y126-A130 WeakPolarHBondContact O-CB 3.21Å; Y126-A130 PolarHBondContact O-N 3.33Å; Y126-Y228 AromaticContact CD1-CD1 3.57Å; Y126-Y228 HydrophobicContact CD1-CD1 3.57Å; Y126-Y228 AromaticContact CD1-CE1 3.59Å; Y126-Y228 HydrophobicContact CD1-CE1 3.59Å; Y126-Y228 HydrophobicContact CE1-CD1 4.08Å; Y126-Y228 HydrophobicContact CE1-CE1 4.1Å; Y126-Q229 HydrophobicContact CD1-CG 4.21Å; Y126-Q229 HydrophobicContact CE1-CB 4.46Å; Y126-Q229 HydrophobicContact CE1-CG 3.83Å; Y126-Q229 HydrophobicContact CE2-CG 4.33Å; Y126-F232 HydrophobicContact CE1-CD1 4.44Å; Y126-W233 AromaticContact CZ-NE1 3.95Å; Y126-W233 VanDerWaalsContact OH-CZ2 3.31Å; Y126-W233 WeakPolarHBondContact OH-CZ2 3.23Å; Y126-W233 PolarHBondContact OH-NE1 3.18Å
127	P	97.2	Very high	96.2	Very high	13 Å²	13	39.6 Å²	39.6	8%	0.084	23%	0.227	C	C	.	.	T	Hydrogen-bonded Turn	trans	-67.7	153.8	157.5	29.6	-31.3	0	0	0	110.3	L129 L206 F217 Y228	P127-L129 VanDerWaalsContact C-N 3.34Å; P127-L206 HydrophobicContact CB-CD1 4.1Å; P127-L206 HydrophobicContact CG-CD1 4.4Å; P127-F217 HydrophobicContact CB-CB 3.86Å; P127-F217 HydrophobicContact CG-CB 3.54Å; P127-F217 HydrophobicContact CG-CD2 3.98Å; P127-F217 HydrophobicContact CG-CG 3.8Å; P127-Y228 VanDerWaalsContact CD-CG 3.41Å; P127-Y228 HydrophobicContact CG-CD1 4.45Å; P127-Y228 HydrophobicContact CG-CD2 4.15Å; P127-Y228 HydrophobicContact CG-CG 3.84Å
128	P	96.9	Very high	96.4	Very high	86 Å²	86	38.5 Å²	38.5	56%	0.558	22%	0.218	S	C	*	.	T	Hydrogen-bonded Turn	cis	-81	-4.8	0.9	33.9	-36.4	0	0	0	114	A130 G131 S134	P128-A130 VanDerWaalsContact C-N 3.3Å; P128-A130 PolarHBondContact O-N 3.38Å; P128-G131 PolarHBondContact O-N 3.26Å; P128-S134 PolarHBondContact O-OG 3.09Å
129	L	97.6	Very high	96.4	Very high	80 Å²	80	38.7 Å²	38.7	42%	0.419	22%	0.219	S	C	.	.	T	Hydrogen-bonded Turn	trans	-61.4	-39.2	-179.7	-178.5	64	0	0	0	111.7	T121 Y126 P127 G131 S134 H135	T121-L129 HydrophobicContact CG2-CG 4.45Å; Y126-L129 WeakPolarHBondContact O-CB 3.37Å; Y126-L129 PolarHBondContact O-N 3.07Å; P127-L129 VanDerWaalsContact C-N 3.34Å; L129-G131 PolarHBondContact O-N 3.24Å; L129-S134 VanDerWaalsContact O-CB 3.27Å; L129-S134 WeakPolarHBondContact O-CB 3.22Å; L129-H135 PolarHBondContact O-ND1 3.5Å
130	A	97.6	Very high	96.5	Very high	0 Å²	0	38.5 Å²	38.5	0%	0	22%	0.217	C	C	.	.	T	Hydrogen-bonded Turn	trans	-79.6	2.9	174.6	0	0	0	0	0	114.1	T121 V125 Y126 P128 V140 L206 R210	T121-A130 HydrophobicContact CG2-CB 3.82Å; V125-A130 HydrophobicContact CG1-CB 3.63Å; V125-A130 WeakPolarHBondContact O-CB 3.37Å; Y126-A130 WeakPolarHBondContact O-CB 3.21Å; Y126-A130 PolarHBondContact O-N 3.33Å; P128-A130 VanDerWaalsContact C-N 3.3Å; P128-A130 PolarHBondContact O-N 3.38Å; A130-V140 HydrophobicContact CB-CG1 4.38Å; A130-L206 HydrophobicContact CB-CD1 4.42Å; A130-L206 HydrophobicContact CB-CD2 3.89Å; A130-R210 WeakPolarHBondContact O-CD 3.5Å; A130-R210 PolarHBondContact O-NH1 3.12Å
131	G	96.3	Very high	96.5	Very high	16 Å²	16	39 Å²	39	17%	0.165	22%	0.219	C	C	.	.	S	Bend	trans	-82.3	168.3	175.7	0	0	0	0	0	113	P128 L129 Y133 S134 H135 R210	P128-G131 PolarHBondContact O-N 3.26Å; L129-G131 PolarHBondContact O-N 3.24Å; G131-Y133 PolarHBondContact O-N 3.46Å; G131-S134 PolarHBondContact O-N 3.27Å; G131-H135 PolarHBondContact O-N 2.78Å; G131-R210 PolarHBondContact O-NH1 2.96Å
132	N	94.1	Very high	96.6	Very high	66 Å²	66	40.5 Å²	40.5	35%	0.353	23%	0.226	S	C	.	.	T	Hydrogen-bonded Turn	trans	-67.7	-19.6	-175.8	-97	-27	0	0	0	114.6	R210	N132-R210 PolarHBondContact ND2-O 3.46Å; N132-R210 PolarHBondContact OD1-NH2 2.92Å; N132-R210 VanDerWaalsContact OD1-NH2 3.07Å
133	Y	92.2	Very high	96.7	Very high	226 Å²	226	40.4 Å²	40.4	89%	0.886	23%	0.225	S	C	*	.	T	Hydrogen-bonded Turn	trans	-67.6	-37.7	174.4	-170.8	-93	0	0	0	112.4	G131	G131-Y133 PolarHBondContact O-N 3.46Å
134	S	95.3	Very high	96.8	Very high	55 Å²	55	38.9 Å²	38.9	39%	0.385	22%	0.219	S	C	.	.	T	Hydrogen-bonded Turn	trans	-101.8	-37.4	-174.4	-52.6	0	0	0	0	112.9	P128 L129 G131	P128-S134 PolarHBondContact O-OG 3.09Å; L129-S134 VanDerWaalsContact O-CB 3.27Å; L129-S134 WeakPolarHBondContact O-CB 3.22Å; G131-S134 PolarHBondContact O-N 3.27Å
135	H	96.9	Very high	96.9	Very high	12 Å²	12	43.6 Å²	43.6	6%	0.056	24%	0.24	C	C	.	.	S	Bend	trans	-122	81.6	174.5	-77.9	76.2	0	0	0	109.1	H49 G120 L129 G131 V140 R210	H49-H135 AromaticContact CE1-CD2 3.99Å; H49-H135 AromaticContact CE1-NE2 3.45Å; H49-H135 PolarHBondContact CE1-NE2 2.71Å; G120-H135 WeakPolarHBondContact CA-NE2 3.34Å; G120-H135 PolarHBondContact N-NE2 3.48Å; G120-H135 VanDerWaalsContact N-NE2 3.16Å; L129-H135 PolarHBondContact O-ND1 3.5Å; G131-H135 PolarHBondContact O-N 2.78Å; H135-V140 HydrophobicContact CB-CG2 3.74Å; H135-R210 PolarHBondContact O-NH1 3.27Å; H135-R210 PolarHBondContact O-NH2 3.12Å
136	P	92.1	Very high	96.9	Very high	90 Å²	90	43.5 Å²	43.5	58%	0.584	24%	0.239	S	C	*	.			trans	-67.7	147.3	174.6	29.5	-34.5	0	0	0	110.3
137	G	94.6	Very high	96.9	Very high	27 Å²	27	41.7 Å²	41.7	28%	0.278	23%	0.232	S	C	.	.	S	Bend	trans	95.3	-168.4	169.4	0	0	0	0	0	115.7	E116 R210	E116-G137 VanDerWaalsContact CD-CA 3.47Å; E116-G137 WeakPolarHBondContact OE1-CA 3.34Å; E116-G137 WeakPolarHBondContact OE2-CA 3.41Å; G137-R210 PolarHBondContact O-NH2 3.24Å
138	A	97.1	Very high	97	Very high	39 Å²	39	43.1 Å²	43.1	32%	0.322	24%	0.238	S	C	.	.	S	Bend	trans	-84.8	-10	-165.3	0	0	0	0	0	114.9	V115 E116 V140 D141 L142	V115-A138 HydrophobicContact CG1-CB 4.39Å; E116-A138 VanDerWaalsContact CD-N 3.27Å; E116-A138 PolarHBondContact OE1-N 2.91Å; E116-A138 PolarHBondContact OE2-N 2.94Å; A138-V140 PolarHBondContact O-N 3.32Å; A138-D141 WeakPolarHBondContact O-CB 3.49Å; A138-D141 PolarHBondContact O-N 3.21Å; A138-D141 VanDerWaalsContact O-N 3.16Å; A138-L142 WeakPolarHBondContact O-CG 3.45Å; A138-L142 PolarHBondContact O-N 3.1Å
139	S	98.1	Very high	97.1	Very high	3 Å²	3	41.5 Å²	41.5	2%	0.021	22%	0.224	C	C	.	.	H	α-helix	trans	-56.5	-50.4	-175	59.5	0	0	0	0	113.1	S112 E116 D141 L142 T143	S112-S139 WeakPolarHBondContact CB-O 3.29Å; S112-S139 PolarHBondContact OG-O 3.42Å; E116-S139 PolarHBondContact OE2-N 3.4Å; S139-D141 VanDerWaalsContact C-N 3.32Å; S139-D141 PolarHBondContact O-N 2.87Å; S139-L142 PolarHBondContact O-N 3.44Å; S139-T143 PolarHBondContact O-N 3.38Å
140	V	98.6	Very high	97.1	Very high	0 Å²	0	37.8 Å²	37.8	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-65.9	-36	178	177.2	0	0	0	0	111.5	A119 T121 V125 A130 H135 A138 L142 T143 I144	A119-V140 HydrophobicContact CB-CG2 4.27Å; T121-V140 HydrophobicContact CG2-CG2 4.08Å; V125-V140 HydrophobicContact CG1-CG1 4.1Å; A130-V140 HydrophobicContact CB-CG1 4.38Å; H135-V140 HydrophobicContact CB-CG2 3.74Å; A138-V140 PolarHBondContact O-N 3.32Å; V140-L142 PolarHBondContact O-N 3.39Å; V140-T143 WeakPolarHBondContact O-CB 3.21Å; V140-T143 PolarHBondContact O-N 3.26Å; V140-T143 VanDerWaalsContact O-N 3.14Å; V140-I144 HydrophobicContact CG1-CD1 4.08Å; V140-I144 HydrophobicContact CG1-CG1 4.48Å; V140-I144 WeakPolarHBondContact O-CG1 3.49Å; V140-I144 PolarHBondContact O-N 3.08Å
141	D	98.5	Very high	97.2	Very high	18 Å²	18	38.3 Å²	38.3	10%	0.096	21%	0.21	C	C	.	.	H	α-helix	trans	-64.2	-41.9	179.3	-60	-11.5	0	0	0	111.2	A138 S139 T143 I144 F145 L207 R210 N211	A138-D141 WeakPolarHBondContact O-CB 3.49Å; A138-D141 PolarHBondContact O-N 3.21Å; A138-D141 VanDerWaalsContact O-N 3.16Å; S139-D141 VanDerWaalsContact C-N 3.32Å; S139-D141 PolarHBondContact O-N 2.87Å; D141-T143 VanDerWaalsContact C-N 3.32Å; D141-T143 PolarHBondContact O-N 3.34Å; D141-I144 WeakPolarHBondContact O-CB 3.12Å; D141-I144 PolarHBondContact O-N 2.72Å; D141-I144 VanDerWaalsContact O-N 3.15Å; D141-F145 HydrophobicContact CB-CE2 4.38Å; D141-F145 WeakPolarHBondContact O-CD2 3.14Å; D141-F145 PolarHBondContact O-N 3.4Å; D141-L207 HydrophobicContact CB-CD1 3.92Å; D141-R210 IonicContact OD1-CZ 3.79Å; D141-R210 IonicContact OD1-NE 2.7Å; D141-R210 PolarHBondContact OD1-NE 3.41Å; D141-R210 IonicContact OD1-NH2 2.68Å; D141-N211 VanDerWaalsContact CG-ND2 3.32Å; D141-N211 PolarHBondContact OD1-ND2 3.5Å; D141-N211 PolarHBondContact OD2-ND2 2.76Å; D141-N211 PolarHBondContact OD2-OD1 3.4Å
142	L	98.7	Very high	97.3	Very high	35 Å²	35	40.7 Å²	40.7	18%	0.183	22%	0.222	C	C	.	.	H	α-helix	trans	-62.7	-37.3	173.6	-68.8	174.7	0	0	0	112.2	L108 A111 V115 A138 S139 V140 F145 S146	L108-L142 HydrophobicContact CD2-CD2 3.75Å; A111-L142 HydrophobicContact CB-CD1 4.27Å; V115-L142 HydrophobicContact CB-CD1 4.18Å; V115-L142 HydrophobicContact CG2-CD1 3.95Å; A138-L142 WeakPolarHBondContact O-CG 3.45Å; A138-L142 PolarHBondContact O-N 3.1Å; S139-L142 PolarHBondContact O-N 3.44Å; V140-L142 PolarHBondContact O-N 3.39Å; L142-F145 PolarHBondContact O-N 2.96Å; L142-S146 WeakPolarHBondContact O-CB 3.43Å; L142-S146 PolarHBondContact O-N 3.38Å
143	T	98.6	Very high	97.5	Very high	2 Å²	2	37.7 Å²	37.7	1%	0.012	21%	0.206	C	C	.	.	H	α-helix	trans	-62.1	-45.9	171.6	-64.7	0	0	0	0	110.5	F60 L109 S112 A119 S139 V140 D141 F145 S146 L147	F60-T143 HydrophobicContact CD2-CG2 4.19Å; F60-T143 HydrophobicContact CE2-CG2 3.58Å; F60-T143 HydrophobicContact CZ-CG2 4.03Å; L109-T143 HydrophobicContact CD1-CG2 4.31Å; S112-T143 PolarHBondContact OG-OG1 2.88Å; A119-T143 WeakPolarHBondContact CB-OG1 3.34Å; S139-T143 PolarHBondContact O-N 3.38Å; V140-T143 WeakPolarHBondContact O-CB 3.21Å; V140-T143 PolarHBondContact O-N 3.26Å; V140-T143 VanDerWaalsContact O-N 3.14Å; D141-T143 VanDerWaalsContact C-N 3.32Å; D141-T143 PolarHBondContact O-N 3.34Å; T143-F145 PolarHBondContact O-N 3.37Å; T143-S146 WeakPolarHBondContact O-CB 3.47Å; T143-S146 PolarHBondContact O-N 2.82Å; T143-L147 HydrophobicContact CG2-CD1 4.27Å; T143-L147 WeakPolarHBondContact O-CG 3.32Å; T143-L147 PolarHBondContact O-N 3.48Å
144	I	98.8	Very high	97.8	Very high	1 Å²	1	28 Å²	28	1%	0.005	17%	0.172	C	C	.	.	H	α-helix	trans	-61.3	-45.5	178.7	-68.5	168.8	0	0	0	110.8	V140 D141 S146 L147 H148 I203 L206 L207	V140-I144 HydrophobicContact CG1-CD1 4.08Å; V140-I144 HydrophobicContact CG1-CG1 4.48Å; V140-I144 WeakPolarHBondContact O-CG1 3.49Å; V140-I144 PolarHBondContact O-N 3.08Å; D141-I144 WeakPolarHBondContact O-CB 3.12Å; D141-I144 PolarHBondContact O-N 2.72Å; D141-I144 VanDerWaalsContact O-N 3.15Å; I144-S146 PolarHBondContact O-N 3.37Å; I144-L147 PolarHBondContact O-N 3.15Å; I144-H148 WeakPolarHBondContact CG2-CE1 3.35Å; I144-H148 WeakPolarHBondContact CG2-ND1 3.37Å; I144-H148 PolarHBondContact O-N 3.2Å; I144-H148 PolarHBondContact O-ND1 2.94Å; I144-I203 HydrophobicContact CG1-CB 4.41Å; I144-I203 HydrophobicContact CG2-CB 4.11Å; I144-I203 HydrophobicContact CG2-CD1 4.24Å; I144-I203 HydrophobicContact CG2-CG1 4.17Å; I144-L206 HydrophobicContact CD1-CD2 4.19Å; I144-L206 HydrophobicContact CD1-CG 4.25Å; I144-L207 HydrophobicContact CD1-CB 4.16Å; I144-L207 HydrophobicContact CD1-CD1 4.13Å; I144-L207 HydrophobicContact CG2-CB 4.23Å; I144-L207 HydrophobicContact CG2-CD1 4.39Å; I144-L207 HydrophobicContact CG2-CD2 4.33Å
145	F	98.8	Very high	97.9	Very high	98 Å²	98	27.5 Å²	27.5	43%	0.43	16%	0.164	S	C	.	.	H	α-helix	trans	-64.5	-38.5	176.7	-71.1	-55.2	0	0	0	112.7	L108 D141 L142 T143 H148 L149 L207	L108-F145 HydrophobicContact CD1-CB 4.06Å; D141-F145 HydrophobicContact CB-CE2 4.38Å; D141-F145 WeakPolarHBondContact O-CD2 3.14Å; D141-F145 PolarHBondContact O-N 3.4Å; L142-F145 PolarHBondContact O-N 2.96Å; T143-F145 PolarHBondContact O-N 3.37Å; F145-H148 PolarHBondContact O-N 3.49Å; F145-L149 PolarHBondContact O-N 2.66Å; F145-L149 VanDerWaalsContact O-N 3.08Å; F145-L207 HydrophobicContact CE1-CD2 3.91Å; F145-L207 HydrophobicContact CZ-CD2 3.89Å
146	S	98.8	Very high	98	Very high	0 Å²	0	28.5 Å²	28.5	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-55.2	-52.5	171.4	162.1	0	0	0	0	110.9	S105 L142 T143 I144 H148 L149 A150	S105-S146 VanDerWaalsContact O-CB 3.32Å; S105-S146 WeakPolarHBondContact O-CB 3.39Å; S105-S146 PolarHBondContact O-OG 3.4Å; S105-S146 VanDerWaalsContact O-OG 3.07Å; S105-S146 PolarHBondContact OG-O 2.92Å; S105-S146 PolarHBondContact OG-OG 3.15Å; L142-S146 WeakPolarHBondContact O-CB 3.43Å; L142-S146 PolarHBondContact O-N 3.38Å; T143-S146 WeakPolarHBondContact O-CB 3.47Å; T143-S146 PolarHBondContact O-N 2.82Å; I144-S146 PolarHBondContact O-N 3.37Å; S146-H148 VanDerWaalsContact C-N 3.33Å; S146-H148 PolarHBondContact O-N 3.49Å; S146-L149 PolarHBondContact O-N 2.94Å; S146-A150 PolarHBondContact O-N 3.12Å
147	L	98.6	Very high	98.3	Very high	8 Å²	8	24.5 Å²	24.5	4%	0.042	14%	0.144	C	C	.	.	H	α-helix	trans	-64.2	-35.7	-178.9	-66.5	177.3	0	0	0	112.7	F60 F64 T143 I144 G151 I203	F60-L147 HydrophobicContact CD1-CD2 3.77Å; F60-L147 HydrophobicContact CE1-CD1 3.74Å; F60-L147 HydrophobicContact CE1-CD2 3.77Å; F60-L147 HydrophobicContact CE1-CG 4.29Å; F60-L147 HydrophobicContact CZ-CD1 3.89Å; F64-L147 HydrophobicContact CD1-CD2 4.39Å; F64-L147 HydrophobicContact CD2-CD2 4.08Å; F64-L147 HydrophobicContact CE1-CD2 4.43Å; F64-L147 HydrophobicContact CE2-CD2 4.08Å; F64-L147 HydrophobicContact CG-CD2 4.25Å; F64-L147 HydrophobicContact CZ-CD2 4.28Å; T143-L147 HydrophobicContact CG2-CD1 4.27Å; T143-L147 WeakPolarHBondContact O-CG 3.32Å; T143-L147 PolarHBondContact O-N 3.48Å; I144-L147 PolarHBondContact O-N 3.15Å; L147-G151 PolarHBondContact O-N 3.45Å; L147-I203 HydrophobicContact CB-CD1 3.86Å
148	H	98.8	Very high	98.5	Very high	43 Å²	43	23.2 Å²	23.2	20%	0.199	13%	0.132	C	C	.	.	H	α-helix	trans	-60.7	-49.1	172.5	-79.8	99	0	0	0	112.2	I144 F145 S146 A150 G151 V152 I203 T204	I144-H148 WeakPolarHBondContact CG2-CE1 3.35Å; I144-H148 WeakPolarHBondContact CG2-ND1 3.37Å; I144-H148 PolarHBondContact O-N 3.2Å; I144-H148 PolarHBondContact O-ND1 2.94Å; F145-H148 PolarHBondContact O-N 3.49Å; S146-H148 VanDerWaalsContact C-N 3.33Å; S146-H148 PolarHBondContact O-N 3.49Å; H148-A150 PolarHBondContact O-N 2.98Å; H148-G151 PolarHBondContact O-N 2.9Å; H148-V152 WeakPolarHBondContact O-CG2 3.11Å; H148-V152 PolarHBondContact O-N 3.34Å; H148-I203 VanDerWaalsContact CE1-CG1 3.45Å; H148-I203 WeakPolarHBondContact CE1-CG1 3.21Å; H148-T204 PolarHBondContact NE2-OG1 2.77Å
149	L	98.7	Very high	98.6	Very high	52 Å²	52	24.2 Å²	24.2	27%	0.272	13%	0.131	S	C	.	.	H	α-helix	trans	-63.9	-41.5	179.8	-70.3	-173.5	0	0	0	112	L101 P104 L108 F145 S146 G151 V152 S153	L101-L149 HydrophobicContact CD2-CD2 4.3Å; P104-L149 HydrophobicContact CB-CD1 4.41Å; L108-L149 HydrophobicContact CD1-CD1 3.65Å; L108-L149 HydrophobicContact CD1-CG 4.5Å; F145-L149 PolarHBondContact O-N 2.66Å; F145-L149 VanDerWaalsContact O-N 3.08Å; S146-L149 PolarHBondContact O-N 2.94Å; L149-G151 VanDerWaalsContact C-N 3.33Å; L149-V152 PolarHBondContact O-N 2.83Å; L149-S153 PolarHBondContact O-N 3.36Å
150	A	98.6	Very high	98.6	Very high	2 Å²	2	24 Å²	24	2%	0.017	13%	0.13	C	C	.	.	H	α-helix	trans	-62	-41.7	173.8	0	0	0	0	0	111.5	F65 L102 S105 S146 H148 S153 S154	F65-A150 HydrophobicContact CZ-CB 4.44Å; L102-A150 HydrophobicContact CD2-CB 4.33Å; S105-A150 PolarHBondContact OG-N 2.88Å; S146-A150 PolarHBondContact O-N 3.12Å; H148-A150 PolarHBondContact O-N 2.98Å; A150-S153 WeakPolarHBondContact O-CB 3.3Å; A150-S153 PolarHBondContact O-N 3.31Å; A150-S154 PolarHBondContact O-N 2.85Å; A150-S154 PolarHBondContact O-OG 3.32Å
151	G	98.4	Very high	98.6	Very high	11 Å²	11	24.2 Å²	24.2	11%	0.113	13%	0.13	C	C	.	.	H	α-helix	trans	-62.1	-44.6	175.8	0	0	0	0	0	112.9	L147 H148 L149 S153 S154 I155	L147-G151 PolarHBondContact O-N 3.45Å; H148-G151 PolarHBondContact O-N 2.9Å; L149-G151 VanDerWaalsContact C-N 3.33Å; G151-S153 PolarHBondContact O-N 2.86Å; G151-S154 PolarHBondContact O-N 3.39Å; G151-I155 WeakPolarHBondContact O-CG1 3.47Å; G151-I155 PolarHBondContact O-N 3.45Å
152	V	98.8	Very high	98.7	Very high	67 Å²	67	24.8 Å²	24.8	41%	0.406	13%	0.133	S	C	.	.	H	α-helix	trans	-61.7	-44	175.4	175.4	0	0	0	0	110.8	L101 H148 L149 S154 I155 L156	L101-V152 HydrophobicContact CD1-CB 4.21Å; L101-V152 HydrophobicContact CD1-CG1 3.68Å; H148-V152 WeakPolarHBondContact O-CG2 3.11Å; H148-V152 PolarHBondContact O-N 3.34Å; L149-V152 PolarHBondContact O-N 2.83Å; V152-S154 VanDerWaalsContact C-N 3.33Å; V152-S154 PolarHBondContact O-N 3.47Å; V152-I155 PolarHBondContact O-N 2.64Å; V152-L156 HydrophobicContact CG1-CD1 4.02Å; V152-L156 HydrophobicContact CG1-CG 4.31Å; V152-L156 VanDerWaalsContact O-CG 3.3Å; V152-L156 WeakPolarHBondContact O-CG 3.45Å; V152-L156 PolarHBondContact O-N 3.3Å
153	S	98.7	Very high	98.7	Very high	3 Å²	3	24.6 Å²	24.6	2%	0.021	13%	0.134	C	C	.	.	H	α-helix	trans	-51.6	-52.1	172.8	156.4	0	0	0	0	111.4	S98 L149 A150 G151 L156 G157	S98-S153 VanDerWaalsContact CB-O 3.28Å; S98-S153 WeakPolarHBondContact CB-O 3.24Å; S98-S153 WeakPolarHBondContact O-CB 3.48Å; S98-S153 PolarHBondContact O-OG 3.47Å; L149-S153 PolarHBondContact O-N 3.36Å; A150-S153 WeakPolarHBondContact O-CB 3.3Å; A150-S153 PolarHBondContact O-N 3.31Å; G151-S153 PolarHBondContact O-N 2.86Å; S153-L156 PolarHBondContact O-N 3.25Å; S153-G157 PolarHBondContact O-N 2.71Å
154	S	98.3	Very high	98.6	Very high	23 Å²	23	24.5 Å²	24.5	16%	0.161	13%	0.133	C	C	.	.	H	α-helix	trans	-68.4	-36.4	-176.2	-65.6	0	0	0	0	113.4	A150 G151 V152 G157 A158	A150-S154 PolarHBondContact O-N 2.85Å; A150-S154 PolarHBondContact O-OG 3.32Å; G151-S154 PolarHBondContact O-N 3.39Å; V152-S154 VanDerWaalsContact C-N 3.33Å; V152-S154 PolarHBondContact O-N 3.47Å; S154-G157 PolarHBondContact O-N 3.2Å; S154-A158 VanDerWaalsContact O-CB 3.3Å; S154-A158 WeakPolarHBondContact O-CB 3.28Å; S154-A158 PolarHBondContact O-N 2.7Å
155	I	98.6	Very high	98.6	Very high	44 Å²	44	24.5 Å²	24.5	23%	0.226	13%	0.133	C	C	.	.	H	α-helix	trans	-64.9	-46.2	175.2	-69.2	168.4	0	0	0	110.9	G151 V152 G157 A158 I159 L193 L196	G151-I155 WeakPolarHBondContact O-CG1 3.47Å; G151-I155 PolarHBondContact O-N 3.45Å; V152-I155 PolarHBondContact O-N 2.64Å; I155-G157 VanDerWaalsContact C-N 3.33Å; I155-G157 PolarHBondContact O-N 3.3Å; I155-A158 PolarHBondContact O-N 3.3Å; I155-I159 HydrophobicContact CG2-CD1 3.97Å; I155-I159 WeakPolarHBondContact O-CG1 3.33Å; I155-I159 PolarHBondContact O-N 3.23Å; I155-L193 HydrophobicContact CG2-CD1 4.19Å; I155-L196 HydrophobicContact CD1-CB 4.02Å; I155-L196 HydrophobicContact CG1-CB 4.02Å; I155-L196 HydrophobicContact CG1-CD1 3.82Å
156	L	98.6	Very high	98.5	Very high	32 Å²	32	24.1 Å²	24.1	17%	0.168	13%	0.134	C	C	.	.	H	α-helix	trans	-60.9	-44.1	177.1	-68.7	178.3	0	0	0	111.2	M94 M97 L101 V152 S153 N160	M94-L156 HydrophobicContact CE-CD2 4.42Å; M94-L156 HydrophobicContact CG-CB 3.87Å; M94-L156 HydrophobicContact CG-CD2 3.95Å; M94-L156 HydrophobicContact CG-CG 4.34Å; M94-L156 HydrophobicContact SD-CB 4.29Å; M94-L156 HydrophobicContact SD-CD2 4.01Å; M97-L156 HydrophobicContact CG-CD1 4.24Å; M97-L156 HydrophobicContact SD-CD1 4.24Å; L101-L156 HydrophobicContact CD1-CD1 4.1Å; V152-L156 HydrophobicContact CG1-CD1 4.02Å; V152-L156 HydrophobicContact CG1-CG 4.31Å; V152-L156 VanDerWaalsContact O-CG 3.3Å; V152-L156 WeakPolarHBondContact O-CG 3.45Å; V152-L156 PolarHBondContact O-N 3.3Å; S153-L156 PolarHBondContact O-N 3.25Å; L156-N160 WeakPolarHBondContact O-CB 3.31Å; L156-N160 PolarHBondContact O-N 2.99Å; L156-N160 VanDerWaalsContact O-N 3.16Å
157	G	98.4	Very high	98.4	Very high	6 Å²	6	29.7 Å²	29.7	6%	0.062	16%	0.164	C	C	.	.	H	α-helix	trans	-59.9	-45.7	173.8	0	0	0	0	0	112.5	S153 S154 I155 I159 N160 F161	S153-G157 PolarHBondContact O-N 2.71Å; S154-G157 PolarHBondContact O-N 3.2Å; I155-G157 VanDerWaalsContact C-N 3.33Å; I155-G157 PolarHBondContact O-N 3.3Å; G157-I159 PolarHBondContact O-N 3.27Å; G157-N160 WeakPolarHBondContact O-CB 3.35Å; G157-N160 PolarHBondContact O-N 3.44Å; G157-F161 WeakPolarHBondContact O-CD2 3.34Å; G157-F161 PolarHBondContact O-N 3.12Å
158	A	98.7	Very high	98.2	Very high	1 Å²	1	32 Å²	32	1%	0.008	18%	0.176	C	C	.	.	H	α-helix	trans	-60.5	-46.5	179.6	0	0	0	0	0	112.7	S154 I155 N160 F161 I162 A189 L192	S154-A158 VanDerWaalsContact O-CB 3.3Å; S154-A158 WeakPolarHBondContact O-CB 3.28Å; S154-A158 PolarHBondContact O-N 2.7Å; I155-A158 PolarHBondContact O-N 3.3Å; A158-N160 VanDerWaalsContact C-N 3.28Å; A158-N160 PolarHBondContact O-N 2.92Å; A158-F161 PolarHBondContact O-N 3.32Å; A158-I162 VanDerWaalsContact O-CG1 3.28Å; A158-I162 WeakPolarHBondContact O-CG1 3.18Å; A158-I162 PolarHBondContact O-N 3.46Å; A158-A189 HydrophobicContact CB-CB 4.04Å; A158-A189 WeakPolarHBondContact CB-O 3.29Å; A158-L192 HydrophobicContact CB-CB 4.02Å
159	I	98.8	Very high	97.9	Very high	59 Å²	59	31.6 Å²	31.6	30%	0.303	17%	0.173	S	C	.	.	H	α-helix	trans	-58.6	-43.4	176.2	-67.5	167	0	0	0	110.4	F91 M94 I155 G157 T163 L193	F91-I159 HydrophobicContact CE2-CG2 4.15Å; M94-I159 HydrophobicContact SD-CG2 4.41Å; I155-I159 HydrophobicContact CG2-CD1 3.97Å; I155-I159 WeakPolarHBondContact O-CG1 3.33Å; I155-I159 PolarHBondContact O-N 3.23Å; G157-I159 PolarHBondContact O-N 3.27Å; I159-T163 WeakPolarHBondContact O-CB 3.47Å; I159-T163 PolarHBondContact O-N 2.99Å; I159-T163 PolarHBondContact O-OG1 3.32Å; I159-L193 HydrophobicContact CD1-CD1 4.39Å; I159-L193 HydrophobicContact CG1-CD1 4.03Å
160	N	98.8	Very high	97.4	Very high	0 Å²	0	29.6 Å²	29.6	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-65.6	-44.6	178.5	-169.8	24.2	0	0	0	112.5	M89 A90 F91 N95 L156 G157 A158 T163 T164	M89-N160 HydrophobicContact CE-CB 4.33Å; M89-N160 WeakPolarHBondContact CE-ND2 3.23Å; A90-N160 PolarHBondContact N-OD1 3.25Å; F91-N160 HydrophobicContact CD2-CB 4.3Å; F91-N160 PolarHBondContact N-OD1 3.45Å; N95-N160 WeakPolarHBondContact CB-ND2 3.38Å; L156-N160 WeakPolarHBondContact O-CB 3.31Å; L156-N160 PolarHBondContact O-N 2.99Å; L156-N160 VanDerWaalsContact O-N 3.16Å; G157-N160 WeakPolarHBondContact O-CB 3.35Å; G157-N160 PolarHBondContact O-N 3.44Å; A158-N160 VanDerWaalsContact C-N 3.28Å; A158-N160 PolarHBondContact O-N 2.92Å; N160-T163 PolarHBondContact O-N 3.4Å; N160-T164 VanDerWaalsContact O-CB 3.27Å; N160-T164 WeakPolarHBondContact O-CB 3.15Å; N160-T164 PolarHBondContact O-N 3.29Å; N160-T164 PolarHBondContact O-OG1 3.27Å; N160-T164 PolarHBondContact OD1-OG1 3.3Å
161	F	98.8	Very high	96.8	Very high	3 Å²	3	35.9 Å²	35.9	1%	0.013	20%	0.204	C	C	.	.	H	α-helix	trans	-61.5	-48.4	175.8	-80.1	-60.8	0	0	0	112.4	I72 G76 V80 M89 G157 A158 T163 T164 I165 V185 A189	I72-F161 HydrophobicContact CG2-CD2 4.11Å; I72-F161 HydrophobicContact CG2-CE2 3.59Å; I72-F161 HydrophobicContact CG2-CZ 4.44Å; I72-F161 VanDerWaalsContact O-CZ 3.29Å; I72-F161 WeakPolarHBondContact O-CZ 3.41Å; G76-F161 VanDerWaalsContact C-CE1 3.46Å; V80-F161 HydrophobicContact CB-CD1 4.41Å; V80-F161 HydrophobicContact CB-CE1 4.28Å; V80-F161 HydrophobicContact CG1-CD1 4.44Å; V80-F161 HydrophobicContact CG2-CD1 4.26Å; V80-F161 HydrophobicContact CG2-CE1 4.17Å; M89-F161 HydrophobicContact CE-CD1 3.47Å; M89-F161 VanDerWaalsContact CE-CD1 3.47Å; M89-F161 HydrophobicContact CE-CE1 3.56Å; M89-F161 HydrophobicContact CE-CG 4.04Å; M89-F161 HydrophobicContact CE-CZ 4.22Å; M89-F161 HydrophobicContact SD-CD1 4.39Å; M89-F161 HydrophobicContact SD-CE1 4.2Å; G157-F161 WeakPolarHBondContact O-CD2 3.34Å; G157-F161 PolarHBondContact O-N 3.12Å; A158-F161 PolarHBondContact O-N 3.32Å; F161-T163 VanDerWaalsContact C-N 3.33Å; F161-T163 PolarHBondContact O-N 3.08Å; F161-T164 PolarHBondContact O-N 2.88Å; F161-I165 WeakPolarHBondContact O-CB 3.2Å; F161-I165 VanDerWaalsContact O-CG1 3.26Å; F161-I165 WeakPolarHBondContact O-CG1 3.37Å; F161-I165 PolarHBondContact O-N 2.91Å; F161-V185 HydrophobicContact CB-CG1 4.3Å; F161-V185 HydrophobicContact CD1-CG1 3.74Å; F161-V185 HydrophobicContact CD2-CG1 4.33Å; F161-V185 HydrophobicContact CE1-CG1 4.17Å; F161-V185 HydrophobicContact CG-CG1 3.87Å; F161-A189 HydrophobicContact CB-CB 4.04Å
162	I	98.8	Very high	96.2	Very high	30 Å²	30	38.3 Å²	38.3	15%	0.154	22%	0.223	C	C	.	.	H	α-helix	trans	-57.1	-50.1	178.8	-68.9	164.8	0	0	0	109.9	A158 T164 I165 I166 L186 A189 V190 L193	A158-I162 VanDerWaalsContact O-CG1 3.28Å; A158-I162 WeakPolarHBondContact O-CG1 3.18Å; A158-I162 PolarHBondContact O-N 3.46Å; I162-T164 PolarHBondContact O-N 3.47Å; I162-I165 PolarHBondContact O-N 3.49Å; I162-I166 HydrophobicContact CG2-CD1 3.7Å; I162-I166 WeakPolarHBondContact O-CB 3.28Å; I162-I166 VanDerWaalsContact O-CG1 3.28Å; I162-I166 WeakPolarHBondContact O-CG1 3.44Å; I162-I166 PolarHBondContact O-N 3.33Å; I162-L186 HydrophobicContact CG1-CD1 4.21Å; I162-A189 HydrophobicContact CD1-CB 4.17Å; I162-A189 HydrophobicContact CG1-CB 3.75Å; I162-V190 HydrophobicContact CD1-CG2 4.06Å; I162-V190 HydrophobicContact CG1-CG2 4.32Å; I162-L193 HydrophobicContact CD1-CD2 4.01Å
163	T	98.6	Very high	95.8	Very high	32 Å²	32	35.8 Å²	35.8	20%	0.196	21%	0.207	C	C	.	.	H	α-helix	trans	-63.1	-43.3	-178.5	-52.9	0	0	0	0	111.5	A90 F91 I159 N160 F161 N167	A90-T163 HydrophobicContact CB-CG2 3.73Å; F91-T163 HydrophobicContact CE2-CG2 3.8Å; F91-T163 WeakPolarHBondContact CE2-OG1 3.33Å; F91-T163 HydrophobicContact CZ-CG2 3.77Å; I159-T163 WeakPolarHBondContact O-CB 3.47Å; I159-T163 PolarHBondContact O-N 2.99Å; I159-T163 PolarHBondContact O-OG1 3.32Å; N160-T163 PolarHBondContact O-N 3.4Å; F161-T163 VanDerWaalsContact C-N 3.33Å; F161-T163 PolarHBondContact O-N 3.08Å; T163-N167 VanDerWaalsContact O-CB 3.27Å; T163-N167 WeakPolarHBondContact O-CB 3.5Å; T163-N167 PolarHBondContact O-N 2.85Å
164	T	98.4	Very high	95.4	Very high	0 Å²	0	39.3 Å²	39.3	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-63.2	-50.8	179.4	-57.5	0	0	0	0	111.1	I84 M89 A90 N160 F161 I162 I166 M168	I84-T164 HydrophobicContact CD1-CG2 3.97Å; M89-T164 HydrophobicContact SD-CG2 3.86Å; A90-T164 WeakPolarHBondContact CB-OG1 3.27Å; A90-T164 PolarHBondContact N-OG1 3.4Å; N160-T164 VanDerWaalsContact O-CB 3.27Å; N160-T164 WeakPolarHBondContact O-CB 3.15Å; N160-T164 PolarHBondContact O-N 3.29Å; N160-T164 PolarHBondContact O-OG1 3.27Å; N160-T164 PolarHBondContact OD1-OG1 3.3Å; F161-T164 PolarHBondContact O-N 2.88Å; I162-T164 PolarHBondContact O-N 3.47Å; T164-I166 VanDerWaalsContact C-N 3.35Å; T164-I166 PolarHBondContact O-N 3.13Å; T164-M168 HydrophobicContact CG2-CB 4.33Å; T164-M168 HydrophobicContact CG2-CG 4.5Å; T164-M168 HydrophobicContact CG2-SD 3.99Å; T164-M168 WeakPolarHBondContact O-CB 3.39Å; T164-M168 PolarHBondContact O-N 3.31Å
165	I	98.3	Very high	95.2	Very high	0 Å²	0	40.3 Å²	40.3	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-66.6	-36.6	-176.3	-65.9	169.6	0	0	0	111.5	V80 F161 I162 K169 V182 V185 L186	V80-I165 HydrophobicContact CG1-CD1 3.99Å; V80-I165 HydrophobicContact CG1-CG1 3.53Å; F161-I165 WeakPolarHBondContact O-CB 3.2Å; F161-I165 VanDerWaalsContact O-CG1 3.26Å; F161-I165 WeakPolarHBondContact O-CG1 3.37Å; F161-I165 PolarHBondContact O-N 2.91Å; I162-I165 PolarHBondContact O-N 3.49Å; I165-K169 VanDerWaalsContact O-CD 3.22Å; I165-K169 WeakPolarHBondContact O-CD 3.39Å; I165-K169 VanDerWaalsContact O-CE 3.3Å; I165-K169 WeakPolarHBondContact O-CE 3.49Å; I165-K169 WeakPolarHBondContact O-CG 3.47Å; I165-K169 PolarHBondContact O-NZ 2.99Å; I165-V182 HydrophobicContact CB-CG1 4.4Å; I165-V182 HydrophobicContact CD1-CG1 3.92Å; I165-V182 HydrophobicContact CG1-CG1 3.85Å; I165-V182 HydrophobicContact CG2-CG1 3.68Å; I165-V185 HydrophobicContact CD1-CB 4.47Å; I165-V185 HydrophobicContact CD1-CG1 4.26Å; I165-L186 HydrophobicContact CB-CD1 4.39Å; I165-L186 HydrophobicContact CD1-CB 3.9Å; I165-L186 HydrophobicContact CD1-CD1 4.47Å; I165-L186 HydrophobicContact CG2-CB 4.3Å; I165-L186 HydrophobicContact CG2-CD1 4.3Å; I165-L186 HydrophobicContact CG2-CD2 4.09Å; I165-L186 HydrophobicContact CG2-CG 4.47Å
166	I	96.6	Very high	94.8	Very high	90 Å²	90	43.6 Å²	43.6	46%	0.462	24%	0.241	S	C	.	.	H	α-helix	trans	-77.5	-44.3	-178.7	-63.9	175.8	0	0	0	110.7	I162 T164 K169	I162-I166 HydrophobicContact CG2-CD1 3.7Å; I162-I166 WeakPolarHBondContact O-CB 3.28Å; I162-I166 VanDerWaalsContact O-CG1 3.28Å; I162-I166 WeakPolarHBondContact O-CG1 3.44Å; I162-I166 PolarHBondContact O-N 3.33Å; T164-I166 VanDerWaalsContact C-N 3.35Å; T164-I166 PolarHBondContact O-N 3.13Å; I166-K169 PolarHBondContact O-NZ 3.43Å
167	N	96.1	Very high	94.5	Very high	118 Å²	118	46 Å²	46	63%	0.631	25%	0.251	S	S	*	.	H	α-helix	trans	-104.8	-19.7	-164.7	-62.8	-31.8	0	0	0	115.7	T163	T163-N167 VanDerWaalsContact O-CB 3.27Å; T163-N167 WeakPolarHBondContact O-CB 3.5Å; T163-N167 PolarHBondContact O-N 2.85Å
168	M	95.2	Very high	94.3	Very high	57 Å²	57	45.7 Å²	45.7	28%	0.281	25%	0.248	S	C	.	.	S	Bend	trans	-103.5	5.3	-171.5	-60.5	-172.3	69.7	0	0	114.8	A86 D88 A90 T164	A86-M168 HydrophobicContact CB-CB 4.03Å; A86-M168 HydrophobicContact CB-CE 4.49Å; D88-M168 WeakPolarHBondContact O-CE 3.48Å; A90-M168 WeakPolarHBondContact CA-SD 3.3Å; A90-M168 HydrophobicContact CB-CG 4.43Å; A90-M168 HydrophobicContact CB-SD 3.61Å; A90-M168 PolarHBondContact N-SD 2.94Å; T164-M168 HydrophobicContact CG2-CB 4.33Å; T164-M168 HydrophobicContact CG2-CG 4.5Å; T164-M168 HydrophobicContact CG2-SD 3.99Å; T164-M168 WeakPolarHBondContact O-CB 3.39Å; T164-M168 PolarHBondContact O-N 3.31Å
169	K	91.8	Very high	94.1	Very high	33 Å²	33	47.1 Å²	47.1	14%	0.143	26%	0.257	C	S	.	.	S	Bend	trans	-68.6	151.6	172.7	-59.5	176.1	-58.9	-118.9	0	110.6	I84 I165 I166 M173 T178	I84-K169 HydrophobicContact CB-CG 4.07Å; I84-K169 HydrophobicContact CD1-CG 4.32Å; I84-K169 HydrophobicContact CG2-CG 4.33Å; I165-K169 VanDerWaalsContact O-CD 3.22Å; I165-K169 WeakPolarHBondContact O-CD 3.39Å; I165-K169 VanDerWaalsContact O-CE 3.3Å; I165-K169 WeakPolarHBondContact O-CE 3.49Å; I165-K169 WeakPolarHBondContact O-CG 3.47Å; I165-K169 PolarHBondContact O-NZ 2.99Å; I166-K169 PolarHBondContact O-NZ 3.43Å; K169-M173 HydrophobicContact CB-CB 4.47Å; K169-M173 HydrophobicContact CB-SD 4.47Å; K169-M173 HydrophobicContact CD-SD 4.21Å; K169-M173 HydrophobicContact CG-SD 4.38Å; K169-T178 HydrophobicContact CD-CG2 3.48Å; K169-T178 VanDerWaalsContact CD-CG2 3.48Å
170	P	88.7	Confident	94	Very high	10 Å²	10	44.5 Å²	44.5	7%	0.065	24%	0.244	C	C	.	.			trans	-52.1	139.5	167.1	-27.1	32.5	0	0	0	111	I84 A172 M173 V506	I84-P170 WeakPolarHBondContact O-CD 3.43Å; P170-A172 PolarHBondContact O-N 2.83Å; P170-M173 PolarHBondContact O-N 2.8Å; P170-V506 HydrophobicContact CG-CB 4.25Å
171	P	85.3	Confident	94	Very high	134 Å²	134	44.5 Å²	44.5	87%	0.87	24%	0.244	S	C	*	.	T	Hydrogen-bonded Turn	trans	-55.4	-25.7	-177.8	-28.6	35.1	0	0	0	115
172	A	86.3	Confident	94	Very high	62 Å²	62	44.4 Å²	44.4	51%	0.512	24%	0.244	S	C	.	.	T	Hydrogen-bonded Turn	trans	-78.2	-17.2	178	0	0	0	0	0	114	P170 M508	P170-A172 PolarHBondContact O-N 2.83Å; A172-M508 HydrophobicContact CB-CB 4.34Å
173	M	89.7	Confident	94	Very high	15 Å²	15	43.7 Å²	43.7	7%	0.074	24%	0.239	C	C	.	.			trans	-90	111.7	-178.2	-176	-175.8	-109.7	0	0	110.7	K169 P170 Q177 T178 M508	K169-M173 HydrophobicContact CB-CB 4.47Å; K169-M173 HydrophobicContact CB-SD 4.47Å; K169-M173 HydrophobicContact CD-SD 4.21Å; K169-M173 HydrophobicContact CG-SD 4.38Å; P170-M173 PolarHBondContact O-N 2.8Å; M173-Q177 HydrophobicContact CG-CB 4.21Å; M173-T178 HydrophobicContact CG-CG2 4.44Å; M173-T178 HydrophobicContact SD-CG2 3.9Å; M173-M508 HydrophobicContact CB-CE 4.15Å; M173-M508 HydrophobicContact CE-CE 3.59Å; M173-M508 HydrophobicContact CE-SD 4.4Å; M173-M508 HydrophobicContact CG-CE 4.07Å
174	T	91.9	Very high	94	Very high	76 Å²	76	42.2 Å²	42.2	47%	0.466	23%	0.23	S	C	.	.			trans	-73.2	159.7	170.3	69.2	0	0	0	0	111.3	Y176 Q177	T174-Y176 PolarHBondContact O-N 3.26Å; T174-Q177 PolarHBondContact O-N 3.49Å; T174-Q177 VanDerWaalsContact OG1-CD 3.31Å; T174-Q177 WeakPolarHBondContact OG1-CG 3.36Å; T174-Q177 PolarHBondContact OG1-OE1 2.9Å
175	Q	92.9	Very high	94	Very high	44 Å²	44	42.2 Å²	42.2	21%	0.206	23%	0.23	C	C	.	.	G	3₁₀ helix	trans	-59.7	-35.5	178.2	-176.7	56.3	36.5	0	0	112.4	Q177 T178 W183	Q175-Q177 PolarHBondContact O-N 2.83Å; Q175-T178 PolarHBondContact NE2-OG1 2.97Å; Q175-T178 PolarHBondContact O-N 3.35Å; Q175-T178 PolarHBondContact O-OG1 3.35Å; Q175-W183 HydrophobicContact CB-CZ2 4.48Å; Q175-W183 HydrophobicContact CG-CH2 3.49Å; Q175-W183 VanDerWaalsContact CG-CH2 3.49Å; Q175-W183 HydrophobicContact CG-CZ2 3.51Å; Q175-W183 HydrophobicContact CG-CZ3 4.29Å; Q175-W183 WeakPolarHBondContact O-CZ2 3.34Å; Q175-W183 PolarHBondContact O-NE1 2.97Å
176	Y	91.4	Very high	94	Very high	113 Å²	113	43 Å²	43	44%	0.443	23%	0.234	S	C	.	.	G	3₁₀ helix	trans	-71.2	-9	176.7	-66.3	-65.6	0	0	0	113.9	T174 W183 Y267 M268 W272	T174-Y176 PolarHBondContact O-N 3.26Å; Y176-W183 HydrophobicContact CD1-CZ2 4.03Å; Y176-W183 HydrophobicContact CE1-CZ2 4.37Å; Y176-Y267 WeakPolarHBondContact O-CE1 3.37Å; Y176-Y267 PolarHBondContact O-OH 2.91Å; Y176-M268 HydrophobicContact CD1-CE 3.48Å; Y176-M268 VanDerWaalsContact CD1-CE 3.48Å; Y176-M268 HydrophobicContact CD1-SD 3.9Å; Y176-M268 HydrophobicContact CE1-CE 3.72Å; Y176-M268 HydrophobicContact CG-CE 4.16Å; Y176-M268 HydrophobicContact CG-SD 4.37Å; Y176-W272 HydrophobicContact CE1-CZ2 4.44Å
177	Q	90.6	Very high	94.1	Very high	82 Å²	82	39.5 Å²	39.5	38%	0.383	22%	0.216	S	C	.	.	G	3₁₀ helix	trans	-97.8	1	174.3	-69.4	163.4	-48.9	0	0	112.8	M173 T174 Q175	M173-Q177 HydrophobicContact CG-CB 4.21Å; T174-Q177 PolarHBondContact O-N 3.49Å; T174-Q177 VanDerWaalsContact OG1-CD 3.31Å; T174-Q177 WeakPolarHBondContact OG1-CG 3.36Å; T174-Q177 PolarHBondContact OG1-OE1 2.9Å; Q175-Q177 PolarHBondContact O-N 2.83Å
178	T	94.1	Very high	94.2	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	19%	0.186	C	C	.	.	S	Bend	trans	-74.4	143.9	179.2	59.3	0	0	0	0	111.9	K169 M173 Q175 W183 Y267	K169-T178 HydrophobicContact CD-CG2 3.48Å; K169-T178 VanDerWaalsContact CD-CG2 3.48Å; M173-T178 HydrophobicContact CG-CG2 4.44Å; M173-T178 HydrophobicContact SD-CG2 3.9Å; Q175-T178 PolarHBondContact NE2-OG1 2.97Å; Q175-T178 PolarHBondContact O-N 3.35Å; Q175-T178 PolarHBondContact O-OG1 3.35Å; T178-W183 VanDerWaalsContact OG1-CD1 3.27Å; T178-W183 PolarHBondContact OG1-NE1 3.17Å; T178-W183 VanDerWaalsContact OG1-NE1 3.1Å; T178-Y267 PolarHBondContact O-OH 3.02Å
179	P	95.4	Very high	94.4	Very high	31 Å²	31	31.2 Å²	31.2	20%	0.201	17%	0.173	C	C	.	.			trans	-61.1	154.2	-178.8	-24.9	35.3	0	0	0	113.9	M83 F181 V182 W183 H253	M83-P179 HydrophobicContact CB-CG 4.2Å; P179-F181 PolarHBondContact O-N 3.11Å; P179-V182 HydrophobicContact CB-CG2 4.39Å; P179-V182 HydrophobicContact CG-CG2 4.44Å; P179-V182 WeakPolarHBondContact O-CA 3.48Å; P179-V182 WeakPolarHBondContact O-CB 3.41Å; P179-V182 PolarHBondContact O-N 2.98Å; P179-W183 PolarHBondContact O-N 3.42Å; P179-W183 VanDerWaalsContact O-N 3.07Å; P179-H253 VanDerWaalsContact CB-CE1 3.43Å; P179-H253 WeakPolarHBondContact CB-CE1 3.26Å; P179-H253 VanDerWaalsContact CB-NE2 3.34Å; P179-H253 WeakPolarHBondContact CB-NE2 3.29Å
180	L	97.4	Very high	94.7	Very high	5 Å²	5	32.5 Å²	32.5	3%	0.026	18%	0.184	C	C	.	.	H	α-helix	trans	-61.9	-29.5	-176.4	-71	-175.9	0	0	0	113.3	S184 P264 Y267 M270 V271 M274	L180-S184 WeakPolarHBondContact O-CB 3.43Å; L180-S184 PolarHBondContact O-N 3.12Å; L180-S184 PolarHBondContact O-OG 3.31Å; L180-P264 HydrophobicContact CD1-CB 4.39Å; L180-P264 HydrophobicContact CD1-CG 3.48Å; L180-P264 VanDerWaalsContact CD1-CG 3.48Å; L180-P264 HydrophobicContact CG-CG 4.32Å; L180-Y267 HydrophobicContact CD1-CD2 4.38Å; L180-Y267 HydrophobicContact CD2-CD2 3.63Å; L180-Y267 HydrophobicContact CD2-CE2 3.48Å; L180-Y267 VanDerWaalsContact CD2-CE2 3.48Å; L180-Y267 HydrophobicContact CG-CD2 3.8Å; L180-Y267 HydrophobicContact CG-CE2 3.81Å; L180-M270 HydrophobicContact CD1-CB 3.96Å; L180-M270 HydrophobicContact CD1-CE 3.76Å; L180-M270 HydrophobicContact CD1-CG 4.44Å; L180-M270 HydrophobicContact CD1-SD 3.6Å; L180-M270 HydrophobicContact CD2-CB 4.16Å; L180-V271 HydrophobicContact CD2-CG2 3.57Å; L180-M274 HydrophobicContact CB-CE 4.44Å; L180-M274 HydrophobicContact CD2-CE 3.75Å
181	F	98.1	Very high	95.2	Very high	0 Å²	0	32.2 Å²	32.2	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-63.3	-44.4	171.7	-178.9	-103.1	0	0	0	111.6	F75 L79 V80 M83 P179 W183 S184 V185 P246 M250 H253	F75-F181 HydrophobicContact CB-CE2 4.38Å; F75-F181 HydrophobicContact CB-CZ 3.78Å; L79-F181 HydrophobicContact CB-CD1 4.09Å; L79-F181 HydrophobicContact CB-CE1 3.75Å; L79-F181 HydrophobicContact CD1-CD1 4.32Å; L79-F181 HydrophobicContact CD1-CE1 4.01Å; L79-F181 HydrophobicContact CD1-CZ 4.29Å; L79-F181 HydrophobicContact CG-CE1 4.47Å; V80-F181 HydrophobicContact CG2-CE1 4.22Å; M83-F181 HydrophobicContact CE-CB 4.5Å; M83-F181 HydrophobicContact CE-CD1 4.4Å; M83-F181 HydrophobicContact SD-CB 3.99Å; M83-F181 HydrophobicContact SD-CD1 3.74Å; M83-F181 HydrophobicContact SD-CG 4.26Å; P179-F181 PolarHBondContact O-N 3.11Å; F181-W183 PolarHBondContact O-N 2.91Å; F181-S184 WeakPolarHBondContact CA-OG 3.28Å; F181-S184 PolarHBondContact O-N 2.89Å; F181-S184 VanDerWaalsContact O-N 3.13Å; F181-S184 PolarHBondContact O-OG 2.9Å; F181-V185 HydrophobicContact CD1-CG2 4.28Å; F181-V185 HydrophobicContact CE1-CG2 3.78Å; F181-V185 HydrophobicContact CE2-CG2 4.11Å; F181-V185 HydrophobicContact CZ-CG2 3.69Å; F181-V185 WeakPolarHBondContact O-CG2 3.18Å; F181-V185 PolarHBondContact O-N 3.45Å; F181-P246 HydrophobicContact CE2-CB 4.26Å; F181-M250 HydrophobicContact CD2-CG 3.72Å; F181-M250 HydrophobicContact CE2-CG 3.62Å; F181-M250 HydrophobicContact CE2-SD 4.43Å; F181-H253 WeakPolarHBondContact CB-NE2 3.4Å; F181-H253 PolarHBondContact N-NE2 3.13Å
182	V	98.4	Very high	95.8	Very high	0 Å²	0	26 Å²	26	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-61.9	-44	177	-179.3	0	0	0	0	111.2	M83 I84 I165 P179 S184 V185 L186	M83-V182 HydrophobicContact CB-CG2 3.71Å; M83-V182 HydrophobicContact SD-CG2 4.29Å; I84-V182 HydrophobicContact CG2-CB 4.45Å; I84-V182 HydrophobicContact CG2-CG1 3.77Å; I84-V182 HydrophobicContact CG2-CG2 3.92Å; I165-V182 HydrophobicContact CB-CG1 4.4Å; I165-V182 HydrophobicContact CD1-CG1 3.92Å; I165-V182 HydrophobicContact CG1-CG1 3.85Å; I165-V182 HydrophobicContact CG2-CG1 3.68Å; P179-V182 HydrophobicContact CB-CG2 4.39Å; P179-V182 HydrophobicContact CG-CG2 4.44Å; P179-V182 WeakPolarHBondContact O-CA 3.48Å; P179-V182 WeakPolarHBondContact O-CB 3.41Å; P179-V182 PolarHBondContact O-N 2.98Å; V182-S184 VanDerWaalsContact C-N 3.32Å; V182-S184 PolarHBondContact O-N 3.43Å; V182-V185 PolarHBondContact O-N 2.99Å; V182-L186 WeakPolarHBondContact O-CB 3.45Å; V182-L186 PolarHBondContact O-N 3.25Å
183	W	98.4	Very high	96.4	Very high	16 Å²	16	26 Å²	26	6%	0.061	13%	0.132	C	C	.	.	H	α-helix	trans	-57.7	-44.5	172.4	-89.4	110.3	0	0	0	112.7	Q175 Y176 T178 P179 F181 V185 L186 I187 Y267 V271 M274 M275	Q175-W183 HydrophobicContact CB-CZ2 4.48Å; Q175-W183 HydrophobicContact CG-CH2 3.49Å; Q175-W183 VanDerWaalsContact CG-CH2 3.49Å; Q175-W183 HydrophobicContact CG-CZ2 3.51Å; Q175-W183 HydrophobicContact CG-CZ3 4.29Å; Q175-W183 WeakPolarHBondContact O-CZ2 3.34Å; Q175-W183 PolarHBondContact O-NE1 2.97Å; Y176-W183 HydrophobicContact CD1-CZ2 4.03Å; Y176-W183 HydrophobicContact CE1-CZ2 4.37Å; T178-W183 VanDerWaalsContact OG1-CD1 3.27Å; T178-W183 PolarHBondContact OG1-NE1 3.17Å; T178-W183 VanDerWaalsContact OG1-NE1 3.1Å; P179-W183 PolarHBondContact O-N 3.42Å; P179-W183 VanDerWaalsContact O-N 3.07Å; F181-W183 PolarHBondContact O-N 2.91Å; W183-V185 VanDerWaalsContact C-N 3.34Å; W183-V185 PolarHBondContact O-N 3.35Å; W183-L186 HydrophobicContact CE3-CD2 4.2Å; W183-L186 HydrophobicContact CZ3-CD2 4.17Å; W183-L186 PolarHBondContact O-N 3.48Å; W183-I187 WeakPolarHBondContact O-CG1 3.34Å; W183-I187 PolarHBondContact O-N 2.92Å; W183-Y267 PolarHBondContact NE1-OH 3.32Å; W183-Y267 VanDerWaalsContact NE1-OH 3.12Å; W183-V271 HydrophobicContact CD2-CG1 3.84Å; W183-V271 HydrophobicContact CD2-CG2 4.41Å; W183-V271 HydrophobicContact CE3-CG1 4.17Å; W183-V271 HydrophobicContact CG-CG1 4.35Å; W183-V271 HydrophobicContact CG-CG2 4.14Å; W183-V271 HydrophobicContact CH2-CG1 4.09Å; W183-V271 HydrophobicContact CZ2-CG1 3.76Å; W183-V271 HydrophobicContact CZ3-CG1 4.3Å; W183-M274 HydrophobicContact CB-CE 3.71Å; W183-M275 HydrophobicContact CH2-SD 4.39Å; W183-M275 HydrophobicContact CZ3-SD 4Å
184	S	98.5	Very high	96.8	Very high	0 Å²	0	30 Å²	30	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-64.1	-39.3	-179.9	73.4	0	0	0	0	112.5	L180 F181 V182 T188 L245 P246	L180-S184 WeakPolarHBondContact O-CB 3.43Å; L180-S184 PolarHBondContact O-N 3.12Å; L180-S184 PolarHBondContact O-OG 3.31Å; F181-S184 WeakPolarHBondContact CA-OG 3.28Å; F181-S184 PolarHBondContact O-N 2.89Å; F181-S184 VanDerWaalsContact O-N 3.13Å; F181-S184 PolarHBondContact O-OG 2.9Å; V182-S184 VanDerWaalsContact C-N 3.32Å; V182-S184 PolarHBondContact O-N 3.43Å; S184-T188 VanDerWaalsContact O-CB 3.31Å; S184-T188 WeakPolarHBondContact O-CB 3.11Å; S184-T188 PolarHBondContact O-N 3.41Å; S184-T188 PolarHBondContact O-OG1 3.38Å; S184-L245 WeakPolarHBondContact CB-O 3.11Å; S184-P246 WeakPolarHBondContact OG-CA 3.19Å
185	V	98.8	Very high	97	Very high	0 Å²	0	26.4 Å²	26.4	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-68.3	-40.6	175	175	0	0	0	0	110.8	I72 V80 F161 I165 F181 V182 W183 T188 A189	I72-V185 HydrophobicContact CD1-CG1 4.4Å; I72-V185 HydrophobicContact CD1-CG2 4.38Å; V80-V185 HydrophobicContact CG2-CB 4.11Å; V80-V185 HydrophobicContact CG2-CG1 3.97Å; V80-V185 HydrophobicContact CG2-CG2 4.11Å; F161-V185 HydrophobicContact CB-CG1 4.3Å; F161-V185 HydrophobicContact CD1-CG1 3.74Å; F161-V185 HydrophobicContact CD2-CG1 4.33Å; F161-V185 HydrophobicContact CE1-CG1 4.17Å; F161-V185 HydrophobicContact CG-CG1 3.87Å; I165-V185 HydrophobicContact CD1-CB 4.47Å; I165-V185 HydrophobicContact CD1-CG1 4.26Å; F181-V185 HydrophobicContact CD1-CG2 4.28Å; F181-V185 HydrophobicContact CE1-CG2 3.78Å; F181-V185 HydrophobicContact CE2-CG2 4.11Å; F181-V185 HydrophobicContact CZ-CG2 3.69Å; F181-V185 WeakPolarHBondContact O-CG2 3.18Å; F181-V185 PolarHBondContact O-N 3.45Å; V182-V185 PolarHBondContact O-N 2.99Å; W183-V185 VanDerWaalsContact C-N 3.34Å; W183-V185 PolarHBondContact O-N 3.35Å; V185-T188 PolarHBondContact O-N 3.21Å; V185-A189 WeakPolarHBondContact O-CB 3.47Å; V185-A189 PolarHBondContact O-N 3.28Å
186	L	98.8	Very high	97.2	Very high	18 Å²	18	24.6 Å²	24.6	9%	0.094	12%	0.123	C	C	.	.	H	α-helix	trans	-59.6	-48.9	176.7	178.5	61.3	0	0	0	111.8	I162 I165 V182 W183 T188 A189 V190	I162-L186 HydrophobicContact CG1-CD1 4.21Å; I165-L186 HydrophobicContact CB-CD1 4.39Å; I165-L186 HydrophobicContact CD1-CB 3.9Å; I165-L186 HydrophobicContact CD1-CD1 4.47Å; I165-L186 HydrophobicContact CG2-CB 4.3Å; I165-L186 HydrophobicContact CG2-CD1 4.3Å; I165-L186 HydrophobicContact CG2-CD2 4.09Å; I165-L186 HydrophobicContact CG2-CG 4.47Å; V182-L186 WeakPolarHBondContact O-CB 3.45Å; V182-L186 PolarHBondContact O-N 3.25Å; W183-L186 HydrophobicContact CE3-CD2 4.2Å; W183-L186 HydrophobicContact CZ3-CD2 4.17Å; W183-L186 PolarHBondContact O-N 3.48Å; L186-T188 VanDerWaalsContact C-N 3.33Å; L186-T188 PolarHBondContact O-N 3.36Å; L186-A189 PolarHBondContact O-N 2.97Å; L186-V190 WeakPolarHBondContact O-CG2 3.23Å; L186-V190 PolarHBondContact O-N 3.33Å; L186-V190 VanDerWaalsContact O-N 3.07Å
187	I	98.8	Very high	97.6	Very high	15 Å²	15	22.3 Å²	22.3	8%	0.077	12%	0.122	C	C	.	.	H	α-helix	trans	-63.2	-45.1	178.9	-64.3	162.7	0	0	0	109.5	W183 A189 V190 L191 L245 M274 M275	W183-I187 WeakPolarHBondContact O-CG1 3.34Å; W183-I187 PolarHBondContact O-N 2.92Å; I187-A189 VanDerWaalsContact C-N 3.32Å; I187-A189 PolarHBondContact O-N 3.39Å; I187-V190 PolarHBondContact O-N 3.32Å; I187-V190 VanDerWaalsContact O-N 3.14Å; I187-L191 HydrophobicContact CG2-CG 4.45Å; I187-L191 WeakPolarHBondContact O-CG 3.37Å; I187-L191 PolarHBondContact O-N 3.17Å; I187-L245 HydrophobicContact CB-CD1 4.42Å; I187-L245 HydrophobicContact CG2-CD1 3.73Å; I187-M274 HydrophobicContact CD1-CB 3.39Å; I187-M275 HydrophobicContact CD1-CG 3.8Å; I187-M275 HydrophobicContact CG1-CG 4.33Å
188	T	98.7	Very high	98	Very high	0 Å²	0	20 Å²	20	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-58.5	-42.7	177.3	-57.4	0	0	0	0	112.3	I72 S184 V185 L186 V190 L191 L192 I242 L245 P246	I72-T188 HydrophobicContact CD1-CG2 3.53Å; I72-T188 HydrophobicContact CG1-CG2 3.91Å; S184-T188 VanDerWaalsContact O-CB 3.31Å; S184-T188 WeakPolarHBondContact O-CB 3.11Å; S184-T188 PolarHBondContact O-N 3.41Å; S184-T188 PolarHBondContact O-OG1 3.38Å; V185-T188 PolarHBondContact O-N 3.21Å; L186-T188 VanDerWaalsContact C-N 3.33Å; L186-T188 PolarHBondContact O-N 3.36Å; T188-V190 VanDerWaalsContact C-N 3.34Å; T188-V190 PolarHBondContact O-N 3.14Å; T188-L191 PolarHBondContact O-N 3.16Å; T188-L192 HydrophobicContact CG2-CD1 4.18Å; T188-L192 WeakPolarHBondContact O-CG 3.31Å; T188-L192 PolarHBondContact O-N 2.95Å; T188-I242 HydrophobicContact CG2-CB 3.91Å; T188-I242 HydrophobicContact CG2-CG1 4Å; T188-I242 HydrophobicContact CG2-CG2 3.59Å; T188-L245 WeakPolarHBondContact OG1-CB 3.4Å; T188-P246 HydrophobicContact CG2-CG 4.3Å
189	A	98.8	Very high	98.1	Very high	1 Å²	1	20.4 Å²	20.4	1%	0.008	12%	0.115	C	C	.	.	H	α-helix	trans	-63.4	-39.1	176.6	0	0	0	0	0	112.1	A158 F161 I162 V185 L186 I187 L192 L193	A158-A189 HydrophobicContact CB-CB 4.04Å; A158-A189 WeakPolarHBondContact CB-O 3.29Å; F161-A189 HydrophobicContact CB-CB 4.04Å; I162-A189 HydrophobicContact CD1-CB 4.17Å; I162-A189 HydrophobicContact CG1-CB 3.75Å; V185-A189 WeakPolarHBondContact O-CB 3.47Å; V185-A189 PolarHBondContact O-N 3.28Å; L186-A189 PolarHBondContact O-N 2.97Å; I187-A189 VanDerWaalsContact C-N 3.32Å; I187-A189 PolarHBondContact O-N 3.39Å; A189-L192 PolarHBondContact O-N 2.84Å; A189-L193 WeakPolarHBondContact O-CB 3.22Å; A189-L193 PolarHBondContact O-N 3.18Å
190	V	98.8	Very high	98.3	Very high	61 Å²	61	20.5 Å²	20.5	37%	0.37	12%	0.119	S	C	.	.	H	α-helix	trans	-64.5	-44.2	173.5	172.2	0	0	0	0	111.2	I162 L186 I187 T188 L192 L193 L194	I162-V190 HydrophobicContact CD1-CG2 4.06Å; I162-V190 HydrophobicContact CG1-CG2 4.32Å; L186-V190 WeakPolarHBondContact O-CG2 3.23Å; L186-V190 PolarHBondContact O-N 3.33Å; L186-V190 VanDerWaalsContact O-N 3.07Å; I187-V190 PolarHBondContact O-N 3.32Å; I187-V190 VanDerWaalsContact O-N 3.14Å; T188-V190 VanDerWaalsContact C-N 3.34Å; T188-V190 PolarHBondContact O-N 3.14Å; V190-L192 PolarHBondContact O-N 3.46Å; V190-L193 PolarHBondContact O-N 2.97Å; V190-L194 HydrophobicContact CG1-CD1 3.91Å; V190-L194 WeakPolarHBondContact O-CG 3.49Å; V190-L194 PolarHBondContact O-N 2.87Å; V190-L194 VanDerWaalsContact O-N 3.14Å
191	L	98.5	Very high	98.4	Very high	4 Å²	4	22.1 Å²	22.1	2%	0.021	13%	0.133	C	C	.	.	H	α-helix	trans	-59.3	-46.2	175.9	-63.6	-174.4	0	0	0	111.3	I187 T188 L193 L194 S195 I242 L245 G278 F282	I187-L191 HydrophobicContact CG2-CG 4.45Å; I187-L191 WeakPolarHBondContact O-CG 3.37Å; I187-L191 PolarHBondContact O-N 3.17Å; T188-L191 PolarHBondContact O-N 3.16Å; L191-L193 PolarHBondContact O-N 3.07Å; L191-L194 PolarHBondContact O-N 3.45Å; L191-S195 VanDerWaalsContact O-CB 3.24Å; L191-S195 WeakPolarHBondContact O-CB 3.23Å; L191-S195 PolarHBondContact O-N 2.66Å; L191-S195 PolarHBondContact O-OG 3.24Å; L191-I242 HydrophobicContact CB-CD1 3.74Å; L191-I242 HydrophobicContact CB-CG1 3.54Å; L191-I242 HydrophobicContact CD1-CG1 4.01Å; L191-I242 HydrophobicContact CG-CG1 4.41Å; L191-L245 HydrophobicContact CD1-CD1 3.66Å; L191-G278 WeakPolarHBondContact CD2-O 3.34Å; L191-F282 HydrophobicContact CD2-CD2 4.07Å; L191-F282 HydrophobicContact CD2-CE2 3.34Å; L191-F282 HydrophobicContact CD2-CZ 4.02Å
192	L	98.1	Very high	98.4	Very high	2 Å²	2	22.3 Å²	22.3	1%	0.01	14%	0.135	C	C	.	.	H	α-helix	trans	-58.6	-47.2	178.6	-78.7	167.1	0	0	0	111.4	M68 A158 T188 A189 V190 L194 L196 I242	M68-L192 HydrophobicContact SD-CD2 4.32Å; A158-L192 HydrophobicContact CB-CB 4.02Å; T188-L192 HydrophobicContact CG2-CD1 4.18Å; T188-L192 WeakPolarHBondContact O-CG 3.31Å; T188-L192 PolarHBondContact O-N 2.95Å; A189-L192 PolarHBondContact O-N 2.84Å; V190-L192 PolarHBondContact O-N 3.46Å; L192-L194 VanDerWaalsContact C-N 3.29Å; L192-L194 PolarHBondContact O-N 2.83Å; L192-L196 HydrophobicContact CB-CD1 4.27Å; L192-L196 HydrophobicContact CD2-CD1 3.71Å; L192-L196 HydrophobicContact CD2-CG 4.23Å; L192-L196 WeakPolarHBondContact O-CB 3.43Å; L192-L196 WeakPolarHBondContact O-CG 3.32Å; L192-L196 PolarHBondContact O-N 3.06Å; L192-L196 VanDerWaalsContact O-N 3.14Å; L192-I242 HydrophobicContact CB-CD1 4.45Å; L192-I242 HydrophobicContact CD1-CG2 4.32Å; L192-I242 HydrophobicContact CD2-CD1 3.73Å; L192-I242 HydrophobicContact CD2-CG1 4.36Å; L192-I242 HydrophobicContact CD2-CG2 3.81Å; L192-I242 HydrophobicContact CG-CD1 3.79Å; L192-I242 HydrophobicContact CG-CG1 4.09Å; L192-I242 HydrophobicContact CG-CG2 3.96Å
193	L	98.1	Very high	98.4	Very high	64 Å²	64	22.4 Å²	22.4	34%	0.335	14%	0.135	S	C	.	.	H	α-helix	trans	-62.3	-36.3	-178.8	-175.8	62.9	0	0	0	112.5	I155 I159 I162 A189 V190 L191 P197	I155-L193 HydrophobicContact CG2-CD1 4.19Å; I159-L193 HydrophobicContact CD1-CD1 4.39Å; I159-L193 HydrophobicContact CG1-CD1 4.03Å; I162-L193 HydrophobicContact CD1-CD2 4.01Å; A189-L193 WeakPolarHBondContact O-CB 3.22Å; A189-L193 PolarHBondContact O-N 3.18Å; V190-L193 PolarHBondContact O-N 2.97Å; L191-L193 PolarHBondContact O-N 3.07Å; L193-P197 VanDerWaalsContact O-CD 3.31Å; L193-P197 WeakPolarHBondContact O-CD 3.37Å; L193-P197 WeakPolarHBondContact O-CG 3.28Å
194	L	98.1	Very high	98.4	Very high	98 Å²	98	24.5 Å²	24.5	51%	0.513	15%	0.15	S	C	.	.	H	α-helix	trans	-87.8	-31	-177	-65.4	177.9	0	0	0	113.6	V190 L191 L192 F282	V190-L194 HydrophobicContact CG1-CD1 3.91Å; V190-L194 WeakPolarHBondContact O-CG 3.49Å; V190-L194 PolarHBondContact O-N 2.87Å; V190-L194 VanDerWaalsContact O-N 3.14Å; L191-L194 PolarHBondContact O-N 3.45Å; L192-L194 VanDerWaalsContact C-N 3.29Å; L192-L194 PolarHBondContact O-N 2.83Å; L194-F282 HydrophobicContact CB-CE1 4.24Å; L194-F282 HydrophobicContact CB-CE2 4.28Å; L194-F282 HydrophobicContact CB-CZ 3.61Å; L194-F282 HydrophobicContact CD1-CE2 4.19Å; L194-F282 HydrophobicContact CD1-CZ 4.36Å
195	S	97.6	Very high	98.4	Very high	0 Å²	0	26.9 Å²	26.9	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-91.6	-40.4	-173.7	61.3	0	0	0	0	113.9	L191 P197 V198	L191-S195 VanDerWaalsContact O-CB 3.24Å; L191-S195 WeakPolarHBondContact O-CB 3.23Å; L191-S195 PolarHBondContact O-N 2.66Å; L191-S195 PolarHBondContact O-OG 3.24Å; S195-P197 VanDerWaalsContact C-CD 3.47Å; S195-V198 PolarHBondContact O-N 3.49Å; S195-V198 VanDerWaalsContact O-N 3.11Å
196	L	97	Very high	98.4	Very high	6 Å²	6	27 Å²	27	3%	0.031	16%	0.162	C	C	.	.	H	α-helix	trans	-61.1	-35.9	-175.8	-75	172.5	0	0	0	115	I155 L192 V198 L199 A200 F235	I155-L196 HydrophobicContact CD1-CB 4.02Å; I155-L196 HydrophobicContact CG1-CB 4.02Å; I155-L196 HydrophobicContact CG1-CD1 3.82Å; L192-L196 HydrophobicContact CB-CD1 4.27Å; L192-L196 HydrophobicContact CD2-CD1 3.71Å; L192-L196 HydrophobicContact CD2-CG 4.23Å; L192-L196 WeakPolarHBondContact O-CB 3.43Å; L192-L196 WeakPolarHBondContact O-CG 3.32Å; L192-L196 PolarHBondContact O-N 3.06Å; L192-L196 VanDerWaalsContact O-N 3.14Å; L196-V198 PolarHBondContact O-N 3.24Å; L196-L199 HydrophobicContact CD2-CD2 4.48Å; L196-L199 PolarHBondContact O-N 3.03Å; L196-A200 PolarHBondContact O-N 3.22Å; L196-F235 HydrophobicContact CD2-CD2 4.12Å; L196-F235 HydrophobicContact CD2-CE2 3.52Å; L196-F235 HydrophobicContact CD2-CZ 4.3Å; L196-F235 HydrophobicContact CG-CE2 4.36Å
197	P	98.4	Very high	98.4	Very high	65 Å²	65	27.4 Å²	27.4	42%	0.422	16%	0.164	S	C	.	.	H	α-helix	trans	-57.9	-32	175	-27.4	36.8	0	0	0	113.4	L193 S195 A201	L193-P197 VanDerWaalsContact O-CD 3.31Å; L193-P197 WeakPolarHBondContact O-CD 3.37Å; L193-P197 WeakPolarHBondContact O-CG 3.28Å; S195-P197 VanDerWaalsContact C-CD 3.47Å; P197-A201 WeakPolarHBondContact O-CB 3.36Å; P197-A201 PolarHBondContact O-N 3.48Å
198	V	98.6	Very high	98.4	Very high	34 Å²	34	28 Å²	28	21%	0.206	17%	0.169	C	C	.	.	H	α-helix	trans	-72.5	-41.7	179.3	-174.9	0	0	0	0	111.1	S195 L196 A201 G202 L231 F234	S195-V198 PolarHBondContact O-N 3.49Å; S195-V198 VanDerWaalsContact O-N 3.11Å; L196-V198 PolarHBondContact O-N 3.24Å; V198-A201 PolarHBondContact O-N 2.89Å; V198-G202 PolarHBondContact O-N 2.96Å; V198-L231 HydrophobicContact CG1-CB 4.32Å; V198-L231 HydrophobicContact CG1-CD2 3.88Å; V198-F234 HydrophobicContact CB-CD1 3.99Å; V198-F234 HydrophobicContact CG1-CB 4.35Å; V198-F234 HydrophobicContact CG1-CD1 3.87Å; V198-F234 HydrophobicContact CG1-CG 4.45Å; V198-F234 HydrophobicContact CG2-CD1 3.69Å; V198-F234 HydrophobicContact CG2-CE1 3.79Å
199	L	98	Very high	98.4	Very high	8 Å²	8	29.5 Å²	29.5	4%	0.042	18%	0.177	C	C	.	.	H	α-helix	trans	-58.4	-52.3	171.3	176.8	67.5	0	0	0	110.5	L196 A201 G202 I203 F232 F235	L196-L199 HydrophobicContact CD2-CD2 4.48Å; L196-L199 PolarHBondContact O-N 3.03Å; L199-A201 VanDerWaalsContact C-N 3.26Å; L199-A201 PolarHBondContact O-N 3.12Å; L199-G202 PolarHBondContact O-N 3.37Å; L199-I203 HydrophobicContact CD1-CG2 3.87Å; L199-I203 HydrophobicContact CG-CD1 4.42Å; L199-I203 HydrophobicContact CG-CG2 4.41Å; L199-I203 WeakPolarHBondContact O-CG1 3.41Å; L199-I203 PolarHBondContact O-N 3.43Å; L199-F232 HydrophobicContact CD1-CD2 3.94Å; L199-F232 HydrophobicContact CD1-CE2 4.1Å; L199-F235 HydrophobicContact CB-CB 3.89Å; L199-F235 HydrophobicContact CB-CD1 3.86Å; L199-F235 HydrophobicContact CB-CD2 3.95Å; L199-F235 HydrophobicContact CB-CE1 4.42Å; L199-F235 HydrophobicContact CB-CG 3.59Å; L199-F235 HydrophobicContact CD1-CD1 3.78Å; L199-F235 HydrophobicContact CD1-CE1 4.11Å; L199-F235 HydrophobicContact CD1-CG 4.4Å; L199-F235 HydrophobicContact CD2-CD1 3.93Å; L199-F235 HydrophobicContact CD2-CD2 4.38Å; L199-F235 HydrophobicContact CD2-CE1 3.64Å; L199-F235 HydrophobicContact CD2-CE2 4.12Å; L199-F235 HydrophobicContact CD2-CG 4.29Å; L199-F235 HydrophobicContact CD2-CZ 3.74Å; L199-F235 HydrophobicContact CG-CD1 4.05Å; L199-F235 HydrophobicContact CG-CE1 4.26Å; L199-F235 HydrophobicContact CG-CG 4.29Å
200	A	98.4	Very high	98.3	Very high	33 Å²	33	29.8 Å²	29.8	27%	0.273	18%	0.177	S	C	.	.	H	α-helix	trans	-55.7	-42.2	-178.4	0	0	0	0	0	111.6	L196 T204	L196-A200 PolarHBondContact O-N 3.22Å; A200-T204 WeakPolarHBondContact O-CB 3.36Å; A200-T204 PolarHBondContact O-N 3.5Å; A200-T204 PolarHBondContact O-OG1 2.7Å
201	A	98.6	Very high	98.3	Very high	40 Å²	40	30.6 Å²	30.6	33%	0.331	18%	0.18	S	C	.	.	H	α-helix	trans	-61.3	-50	173.9	0	0	0	0	0	111.9	P197 V198 L199 T204 M205	P197-A201 WeakPolarHBondContact O-CB 3.36Å; P197-A201 PolarHBondContact O-N 3.48Å; V198-A201 PolarHBondContact O-N 2.89Å; L199-A201 VanDerWaalsContact C-N 3.26Å; L199-A201 PolarHBondContact O-N 3.12Å; A201-T204 PolarHBondContact O-N 3.5Å; A201-M205 HydrophobicContact CB-CE 4.38Å; A201-M205 VanDerWaalsContact O-CG 3.27Å; A201-M205 WeakPolarHBondContact O-CG 3.34Å; A201-M205 PolarHBondContact O-N 3.43Å
202	G	98.6	Very high	98.3	Very high	3 Å²	3	36.3 Å²	36.3	3%	0.031	21%	0.21	C	C	.	.	H	α-helix	trans	-61.3	-45.4	-179.4	0	0	0	0	0	113.7	V198 L199 M205 L206	V198-G202 PolarHBondContact O-N 2.96Å; L199-G202 PolarHBondContact O-N 3.37Å; G202-M205 PolarHBondContact O-N 2.85Å; G202-L206 PolarHBondContact O-N 2.96Å
203	I	98.6	Very high	98.2	Very high	3 Å²	3	43.4 Å²	43.4	2%	0.015	25%	0.248	C	C	.	.	H	α-helix	trans	-74.8	-25.7	178.3	66.3	176.6	0	0	0	112.6	I144 L147 H148 L199 L207	I144-I203 HydrophobicContact CG1-CB 4.41Å; I144-I203 HydrophobicContact CG2-CB 4.11Å; I144-I203 HydrophobicContact CG2-CD1 4.24Å; I144-I203 HydrophobicContact CG2-CG1 4.17Å; L147-I203 HydrophobicContact CB-CD1 3.86Å; H148-I203 VanDerWaalsContact CE1-CG1 3.45Å; H148-I203 WeakPolarHBondContact CE1-CG1 3.21Å; L199-I203 HydrophobicContact CD1-CG2 3.87Å; L199-I203 HydrophobicContact CG-CD1 4.42Å; L199-I203 HydrophobicContact CG-CG2 4.41Å; L199-I203 WeakPolarHBondContact O-CG1 3.41Å; L199-I203 PolarHBondContact O-N 3.43Å; I203-L207 WeakPolarHBondContact O-CB 2.91Å; I203-L207 PolarHBondContact O-N 2.99Å
204	T	98.8	Very high	98.2	Very high	60 Å²	60	42.6 Å²	42.6	37%	0.368	25%	0.246	S	C	.	.	H	α-helix	trans	-68.8	-45.8	169.9	-63.3	0	0	0	0	110.8	H148 A200 A201 L206 L207 T208	H148-T204 PolarHBondContact NE2-OG1 2.77Å; A200-T204 WeakPolarHBondContact O-CB 3.36Å; A200-T204 PolarHBondContact O-N 3.5Å; A200-T204 PolarHBondContact O-OG1 2.7Å; A201-T204 PolarHBondContact O-N 3.5Å; T204-L206 PolarHBondContact O-N 2.91Å; T204-L207 WeakPolarHBondContact O-CB 3.19Å; T204-L207 PolarHBondContact O-N 3.12Å; T204-L207 VanDerWaalsContact O-N 3.08Å; T204-T208 WeakPolarHBondContact O-CG2 3.24Å; T204-T208 PolarHBondContact O-N 3.21Å
205	M	98.7	Very high	98.1	Very high	49 Å²	49	40.9 Å²	40.9	24%	0.241	24%	0.239	C	C	.	.	H	α-helix	trans	-56.8	-40.6	173.8	-70.5	170.2	-167.6	0	0	111	A201 G202 T208 D209 F216 F217 L231	A201-M205 HydrophobicContact CB-CE 4.38Å; A201-M205 VanDerWaalsContact O-CG 3.27Å; A201-M205 WeakPolarHBondContact O-CG 3.34Å; A201-M205 PolarHBondContact O-N 3.43Å; G202-M205 PolarHBondContact O-N 2.85Å; M205-T208 PolarHBondContact O-N 3.48Å; M205-T208 PolarHBondContact O-OG1 2.86Å; M205-D209 PolarHBondContact O-N 3.17Å; M205-F216 HydrophobicContact CB-CB 4.19Å; M205-F216 HydrophobicContact CB-CD2 3.69Å; M205-F216 HydrophobicContact CB-CE2 4.18Å; M205-F216 HydrophobicContact CB-CG 3.89Å; M205-F216 HydrophobicContact CG-CD1 4.12Å; M205-F216 HydrophobicContact CG-CD2 3.88Å; M205-F216 HydrophobicContact CG-CE1 4.19Å; M205-F216 HydrophobicContact CG-CE2 3.96Å; M205-F216 HydrophobicContact CG-CG 3.97Å; M205-F216 HydrophobicContact CG-CZ 4.12Å; M205-F216 HydrophobicContact SD-CD1 4.07Å; M205-F216 HydrophobicContact SD-CE1 4.35Å; M205-F216 HydrophobicContact SD-CG 4.31Å; M205-F217 HydrophobicContact CB-CE2 3.61Å; M205-F217 HydrophobicContact CB-CZ 3.65Å; M205-F217 HydrophobicContact CG-CZ 4.5Å; M205-F217 HydrophobicContact SD-CZ 4.07Å; M205-L231 HydrophobicContact SD-CD1 3.94Å
206	L	98.6	Very high	98.2	Very high	2 Å²	2	45 Å²	45	1%	0.01	26%	0.257	C	S	.	.	H	α-helix	trans	-66.1	-41	176.4	179.9	62.4	0	0	0	111.2	V125 P127 A130 I144 G202 T204 T208 D209 R210 F217 Y228	V125-L206 HydrophobicContact CG1-CD2 3.84Å; P127-L206 HydrophobicContact CB-CD1 4.1Å; P127-L206 HydrophobicContact CG-CD1 4.4Å; A130-L206 HydrophobicContact CB-CD1 4.42Å; A130-L206 HydrophobicContact CB-CD2 3.89Å; I144-L206 HydrophobicContact CD1-CD2 4.19Å; I144-L206 HydrophobicContact CD1-CG 4.25Å; G202-L206 PolarHBondContact O-N 2.96Å; T204-L206 PolarHBondContact O-N 2.91Å; L206-T208 VanDerWaalsContact C-N 3.31Å; L206-T208 PolarHBondContact O-N 3.31Å; L206-D209 PolarHBondContact O-N 3.23Å; L206-R210 VanDerWaalsContact O-CG 3.28Å; L206-R210 WeakPolarHBondContact O-CG 3.49Å; L206-R210 PolarHBondContact O-N 3.42Å; L206-F217 HydrophobicContact CB-CD2 4.33Å; L206-F217 HydrophobicContact CB-CE2 4Å; L206-F217 HydrophobicContact CD1-CD2 4.28Å; L206-Y228 HydrophobicContact CB-CE2 4.19Å; L206-Y228 HydrophobicContact CD2-CE2 3.97Å
207	L	98.6	Very high	98.2	Very high	28 Å²	28	44.9 Å²	44.9	15%	0.147	26%	0.257	C	S	.	.	H	α-helix	trans	-62	-38.9	176.1	-171.4	68.6	0	0	0	111.8	D141 I144 F145 I203 T204 R210 N211	D141-L207 HydrophobicContact CB-CD1 3.92Å; I144-L207 HydrophobicContact CD1-CB 4.16Å; I144-L207 HydrophobicContact CD1-CD1 4.13Å; I144-L207 HydrophobicContact CG2-CB 4.23Å; I144-L207 HydrophobicContact CG2-CD1 4.39Å; I144-L207 HydrophobicContact CG2-CD2 4.33Å; F145-L207 HydrophobicContact CE1-CD2 3.91Å; F145-L207 HydrophobicContact CZ-CD2 3.89Å; I203-L207 WeakPolarHBondContact O-CB 2.91Å; I203-L207 PolarHBondContact O-N 2.99Å; T204-L207 WeakPolarHBondContact O-CB 3.19Å; T204-L207 PolarHBondContact O-N 3.12Å; T204-L207 VanDerWaalsContact O-N 3.08Å; L207-R210 PolarHBondContact O-N 3.2Å; L207-N211 WeakPolarHBondContact CD1-ND2 3.48Å; L207-N211 WeakPolarHBondContact O-CB 3.37Å; L207-N211 PolarHBondContact O-N 3.33Å; L207-N211 PolarHBondContact O-ND2 3.43Å
208	T	98.4	Very high	98.1	Very high	28 Å²	28	45.5 Å²	45.5	17%	0.172	26%	0.256	C	S	.	.	H	α-helix	trans	-73.3	-34.6	176.3	62.9	0	0	0	0	112.2	T204 M205 L206 R210 N211 L212 N213 T214	T204-T208 WeakPolarHBondContact O-CG2 3.24Å; T204-T208 PolarHBondContact O-N 3.21Å; M205-T208 PolarHBondContact O-N 3.48Å; M205-T208 PolarHBondContact O-OG1 2.86Å; L206-T208 VanDerWaalsContact C-N 3.31Å; L206-T208 PolarHBondContact O-N 3.31Å; T208-R210 VanDerWaalsContact C-N 3.26Å; T208-R210 PolarHBondContact O-N 2.85Å; T208-N211 PolarHBondContact O-N 2.9Å; T208-L212 HydrophobicContact CG2-CD1 3.87Å; T208-L212 CarbonylContact O-C 3.49Å; T208-L212 WeakPolarHBondContact O-CA 3.27Å; T208-L212 PolarHBondContact O-N 2.88Å; T208-N213 PolarHBondContact O-N 3.05Å; T208-T214 VanDerWaalsContact CB-OG1 3.32Å; T208-T214 WeakPolarHBondContact CB-OG1 3.32Å; T208-T214 PolarHBondContact O-N 2.96Å; T208-T214 PolarHBondContact O-OG1 3.2Å; T208-T214 PolarHBondContact OG1-OG1 2.6Å
209	D	98.3	Very high	98	Very high	30 Å²	30	47.8 Å²	47.8	16%	0.16	27%	0.272	C	S	.	.	H	α-helix	trans	-63.7	-37.1	173.4	-85.1	15.7	0	0	0	110.7	M205 L206 T214 T215 F216 F217	M205-D209 PolarHBondContact O-N 3.17Å; L206-D209 PolarHBondContact O-N 3.23Å; D209-T214 WeakPolarHBondContact CA-O 3.33Å; D209-T214 WeakPolarHBondContact CA-OG1 3.5Å; D209-T214 PolarHBondContact N-OG1 2.88Å; D209-T214 WeakPolarHBondContact OD1-CB 3.28Å; D209-T214 VanDerWaalsContact OD1-O 3.11Å; D209-T214 PolarHBondContact OD1-OG1 3.5Å; D209-T215 PolarHBondContact OD1-N 2.79Å; D209-T215 VanDerWaalsContact OD1-N 3.13Å; D209-F216 VanDerWaalsContact CG-N 3.32Å; D209-F216 WeakPolarHBondContact OD1-CD2 3.41Å; D209-F216 PolarHBondContact OD1-N 3.35Å; D209-F216 PolarHBondContact OD2-N 2.77Å; D209-F217 PolarHBondContact OD2-N 3.27Å
210	R	97.8	Very high	97.9	Very high	7 Å²	7	52 Å²	52	3%	0.026	31%	0.308	C	S	.	.	H	α-helix	trans	-68.6	-51.4	173.9	-68.6	175	64.2	68.5	9.5	111.5	A130 G131 N132 H135 G137 D141 L206 L207 T208	A130-R210 WeakPolarHBondContact O-CD 3.5Å; A130-R210 PolarHBondContact O-NH1 3.12Å; G131-R210 PolarHBondContact O-NH1 2.96Å; N132-R210 PolarHBondContact ND2-O 3.46Å; N132-R210 PolarHBondContact OD1-NH2 2.92Å; N132-R210 VanDerWaalsContact OD1-NH2 3.07Å; H135-R210 PolarHBondContact O-NH1 3.27Å; H135-R210 PolarHBondContact O-NH2 3.12Å; G137-R210 PolarHBondContact O-NH2 3.24Å; D141-R210 IonicContact OD1-CZ 3.79Å; D141-R210 IonicContact OD1-NE 2.7Å; D141-R210 PolarHBondContact OD1-NE 3.41Å; D141-R210 IonicContact OD1-NH2 2.68Å; L206-R210 VanDerWaalsContact O-CG 3.28Å; L206-R210 WeakPolarHBondContact O-CG 3.49Å; L206-R210 PolarHBondContact O-N 3.42Å; L207-R210 PolarHBondContact O-N 3.2Å; T208-R210 VanDerWaalsContact C-N 3.26Å; T208-R210 PolarHBondContact O-N 2.85Å
211	N	98.1	Very high	97.7	Very high	79 Å²	79	52.4 Å²	52.4	42%	0.422	32%	0.315	S	S	.	.	H	α-helix	trans	-108.8	-17.9	-160.8	-69.4	-66	0	0	0	115.9	D141 L207 T208	D141-N211 VanDerWaalsContact CG-ND2 3.32Å; D141-N211 PolarHBondContact OD1-ND2 3.5Å; D141-N211 PolarHBondContact OD2-ND2 2.76Å; D141-N211 PolarHBondContact OD2-OD1 3.4Å; L207-N211 WeakPolarHBondContact CD1-ND2 3.48Å; L207-N211 WeakPolarHBondContact O-CB 3.37Å; L207-N211 PolarHBondContact O-N 3.33Å; L207-N211 PolarHBondContact O-ND2 3.43Å; T208-N211 PolarHBondContact O-N 2.9Å
212	L	97.8	Very high	97.6	Very high	124 Å²	124	53.9 Å²	53.9	65%	0.649	33%	0.334	S	S	*	.	S	Bend	trans	-122.3	14.5	-173	-58.1	-177.8	0	0	0	113.3	T208 T214	T208-L212 HydrophobicContact CG2-CD1 3.87Å; T208-L212 CarbonylContact O-C 3.49Å; T208-L212 WeakPolarHBondContact O-CA 3.27Å; T208-L212 PolarHBondContact O-N 2.88Å; L212-T214 PolarHBondContact O-N 3.17Å
213	N	96.1	Very high	97.5	Very high	151 Å²	151	54.5 Å²	54.5	81%	0.807	34%	0.34	S	S	*	.			trans	54.6	31.7	-179.9	-57.6	-47.8	0	0	0	113.7	T208	T208-N213 PolarHBondContact O-N 3.05Å
214	T	98	Very high	97.5	Very high	47 Å²	47	57.9 Å²	57.9	29%	0.288	36%	0.359	S	S	.	.			trans	-77	166.4	164.4	63.3	0	0	0	0	109.9	T208 D209 L212 F216	T208-T214 VanDerWaalsContact CB-OG1 3.32Å; T208-T214 WeakPolarHBondContact CB-OG1 3.32Å; T208-T214 PolarHBondContact O-N 2.96Å; T208-T214 PolarHBondContact O-OG1 3.2Å; T208-T214 PolarHBondContact OG1-OG1 2.6Å; D209-T214 WeakPolarHBondContact CA-O 3.33Å; D209-T214 WeakPolarHBondContact CA-OG1 3.5Å; D209-T214 PolarHBondContact N-OG1 2.88Å; D209-T214 WeakPolarHBondContact OD1-CB 3.28Å; D209-T214 VanDerWaalsContact OD1-O 3.11Å; D209-T214 PolarHBondContact OD1-OG1 3.5Å; L212-T214 PolarHBondContact O-N 3.17Å; T214-F216 HydrophobicContact CG2-CE2 4.32Å
215	T	97.6	Very high	97.5	Very high	62 Å²	62	56.3 Å²	56.3	38%	0.38	35%	0.349	S	S	.	.			trans	-138.2	50.4	-176.2	58.5	0	0	0	0	111.4	D209 D218 G221 G223	D209-T215 PolarHBondContact OD1-N 2.79Å; D209-T215 VanDerWaalsContact OD1-N 3.13Å; T215-D218 HydrophobicContact CG2-CB 4.45Å; T215-G221 PolarHBondContact OG1-O 3.49Å; T215-G223 VanDerWaalsContact O-CA 3.26Å; T215-G223 WeakPolarHBondContact O-CA 3.35Å; T215-G223 PolarHBondContact O-N 3.02Å
216	F	98.4	Very high	97.4	Very high	87 Å²	87	56.6 Å²	56.6	38%	0.382	35%	0.351	S	S	.	.	S	Bend	trans	-63.9	-40.8	175.9	-72.9	-76.2	0	0	0	112	M205 D209 T214 G223 D224	M205-F216 HydrophobicContact CB-CB 4.19Å; M205-F216 HydrophobicContact CB-CD2 3.69Å; M205-F216 HydrophobicContact CB-CE2 4.18Å; M205-F216 HydrophobicContact CB-CG 3.89Å; M205-F216 HydrophobicContact CG-CD1 4.12Å; M205-F216 HydrophobicContact CG-CD2 3.88Å; M205-F216 HydrophobicContact CG-CE1 4.19Å; M205-F216 HydrophobicContact CG-CE2 3.96Å; M205-F216 HydrophobicContact CG-CG 3.97Å; M205-F216 HydrophobicContact CG-CZ 4.12Å; M205-F216 HydrophobicContact SD-CD1 4.07Å; M205-F216 HydrophobicContact SD-CE1 4.35Å; M205-F216 HydrophobicContact SD-CG 4.31Å; D209-F216 VanDerWaalsContact CG-N 3.32Å; D209-F216 WeakPolarHBondContact OD1-CD2 3.41Å; D209-F216 PolarHBondContact OD1-N 3.35Å; D209-F216 PolarHBondContact OD2-N 2.77Å; T214-F216 HydrophobicContact CG2-CE2 4.32Å; F216-G223 WeakPolarHBondContact O-CA 3.47Å; F216-D224 PolarHBondContact O-N 2.89Å; F216-D224 VanDerWaalsContact O-N 3.09Å
217	F	98.3	Very high	97.4	Very high	3 Å²	3	60 Å²	60	1%	0.013	37%	0.369	C	S	.	.	S	Bend	trans	-118.8	-2.7	-173.3	-48	-54.8	0	0	0	113.6	P127 M205 L206 D209 P219 P225 L227 Y228 L231	P127-F217 HydrophobicContact CB-CB 3.86Å; P127-F217 HydrophobicContact CG-CB 3.54Å; P127-F217 HydrophobicContact CG-CD2 3.98Å; P127-F217 HydrophobicContact CG-CG 3.8Å; M205-F217 HydrophobicContact CB-CE2 3.61Å; M205-F217 HydrophobicContact CB-CZ 3.65Å; M205-F217 HydrophobicContact CG-CZ 4.5Å; M205-F217 HydrophobicContact SD-CZ 4.07Å; L206-F217 HydrophobicContact CB-CD2 4.33Å; L206-F217 HydrophobicContact CB-CE2 4Å; L206-F217 HydrophobicContact CD1-CD2 4.28Å; D209-F217 PolarHBondContact OD2-N 3.27Å; F217-P219 WeakPolarHBondContact O-CD 3.46Å; F217-P225 VanDerWaalsContact O-CD 3.26Å; F217-P225 WeakPolarHBondContact O-CD 3.26Å; F217-P225 VanDerWaalsContact O-CG 3.3Å; F217-P225 WeakPolarHBondContact O-CG 3.41Å; F217-L227 HydrophobicContact CD1-CB 4.41Å; F217-L227 HydrophobicContact CE1-CB 4.33Å; F217-L227 HydrophobicContact CE1-CD2 4.16Å; F217-L227 HydrophobicContact CE1-CG 4.11Å; F217-Y228 HydrophobicContact CD2-CD2 4.1Å; F217-Y228 HydrophobicContact CE1-CD2 4.24Å; F217-Y228 HydrophobicContact CE1-CG 4.47Å; F217-Y228 AromaticContact CE2-CD2 3.61Å; F217-Y228 HydrophobicContact CE2-CD2 3.61Å; F217-Y228 HydrophobicContact CE2-CE2 4.47Å; F217-Y228 HydrophobicContact CE2-CG 4.48Å; F217-Y228 AromaticContact CZ-CD2 3.69Å; F217-Y228 HydrophobicContact CZ-CD2 3.69Å; F217-Y228 HydrophobicContact CZ-CG 4.35Å; F217-L231 HydrophobicContact CE1-CD1 4.31Å; F217-L231 HydrophobicContact CZ-CD1 4.27Å
218	D	96.4	Very high	97.4	Very high	77 Å²	77	58.8 Å²	58.8	41%	0.412	36%	0.363	S	S	.	.			trans	-88.7	112.2	177.3	-176.9	1	0	0	0	111.5	T215 A220 G221 G222 G223	T215-D218 HydrophobicContact CG2-CB 4.45Å; D218-A220 PolarHBondContact O-N 2.95Å; D218-A220 WeakPolarHBondContact OD1-CB 3.35Å; D218-A220 PolarHBondContact OD1-N 3.49Å; D218-G221 PolarHBondContact O-N 2.82Å; D218-G222 PolarHBondContact O-N 3.39Å; D218-G223 WeakPolarHBondContact O-CA 3.22Å; D218-G223 PolarHBondContact O-N 2.84Å
219	P	95.9	Very high	97.4	Very high	83 Å²	83	59.2 Å²	59.2	54%	0.539	36%	0.363	S	S	.	.	G	3₁₀ helix	trans	-58.9	-27.1	177.4	-24.1	35.5	0	0	0	114.4	F217 G221 G222 G223 P225	F217-P219 WeakPolarHBondContact O-CD 3.46Å; P219-G221 PolarHBondContact O-N 3.45Å; P219-G222 PolarHBondContact O-N 2.93Å; P219-G222 VanDerWaalsContact O-N 3.08Å; P219-G223 WeakPolarHBondContact CA-O 3.22Å; P219-P225 HydrophobicContact CG-CG 4.1Å
220	A	94.9	Very high	97.4	Very high	96 Å²	96	61 Å²	61	79%	0.793	37%	0.37	S	S	*	.	G	3₁₀ helix	trans	-65.2	-27.4	177.9	0	0	0	0	0	112.3	D218	D218-A220 PolarHBondContact O-N 2.95Å; D218-A220 WeakPolarHBondContact OD1-CB 3.35Å; D218-A220 PolarHBondContact OD1-N 3.49Å
221	G	94.9	Very high	97.5	Very high	41 Å²	41	62.4 Å²	62.4	42%	0.423	38%	0.378	S	S	.	.	G	3₁₀ helix	trans	-100.1	9.5	172.8	0	0	0	0	0	114.5	T215 D218 P219	T215-G221 PolarHBondContact OG1-O 3.49Å; D218-G221 PolarHBondContact O-N 2.82Å; P219-G221 PolarHBondContact O-N 3.45Å
222	G	96.3	Very high	97.5	Very high	72 Å²	72	59 Å²	59	74%	0.742	36%	0.359	S	S	*	.	T	Hydrogen-bonded Turn	trans	85.4	9.4	-178.1	0	0	0	0	0	115.6	D218 P219	D218-G222 PolarHBondContact O-N 3.39Å; P219-G222 PolarHBondContact O-N 2.93Å; P219-G222 VanDerWaalsContact O-N 3.08Å
223	G	97.8	Very high	97.5	Very high	15 Å²	15	53.5 Å²	53.5	16%	0.155	33%	0.33	C	S	.	.			trans	-77.4	171	173.2	0	0	0	0	0	113.5	T215 F216 D218 P219	T215-G223 VanDerWaalsContact O-CA 3.26Å; T215-G223 WeakPolarHBondContact O-CA 3.35Å; T215-G223 PolarHBondContact O-N 3.02Å; F216-G223 WeakPolarHBondContact O-CA 3.47Å; D218-G223 WeakPolarHBondContact O-CA 3.22Å; D218-G223 PolarHBondContact O-N 2.84Å; P219-G223 WeakPolarHBondContact CA-O 3.22Å
224	D	97.9	Very high	97.7	Very high	75 Å²	75	49.2 Å²	49.2	40%	0.401	30%	0.304	S	S	.	.			trans	-134.2	114.3	-178.8	-176.6	4.4	0	0	0	111.9	F216 I226 L227	F216-D224 PolarHBondContact O-N 2.89Å; F216-D224 VanDerWaalsContact O-N 3.09Å; D224-I226 PolarHBondContact O-N 3.43Å; D224-I226 WeakPolarHBondContact OD1-CB 3.48Å; D224-I226 PolarHBondContact OD1-N 2.96Å; D224-L227 HydrophobicContact CB-CB 4.32Å; D224-L227 VanDerWaalsContact O-CB 3.24Å; D224-L227 WeakPolarHBondContact O-CB 3.25Å; D224-L227 PolarHBondContact O-N 3.43Å
225	P	97.6	Very high	97.7	Very high	26 Å²	26	47 Å²	47	17%	0.169	29%	0.29	C	S	.	.	H	α-helix	trans	-57.6	-26.4	172.8	-24.3	32.8	0	0	0	114.3	F217 P219 L227 Y228 Q229	F217-P225 VanDerWaalsContact O-CD 3.26Å; F217-P225 WeakPolarHBondContact O-CD 3.26Å; F217-P225 VanDerWaalsContact O-CG 3.3Å; F217-P225 WeakPolarHBondContact O-CG 3.41Å; P219-P225 HydrophobicContact CG-CG 4.1Å; P225-L227 VanDerWaalsContact C-N 3.3Å; P225-Y228 WeakPolarHBondContact O-CB 3.27Å; P225-Y228 PolarHBondContact O-N 3.28Å; P225-Q229 PolarHBondContact O-N 2.95Å
226	I	98.3	Very high	97.6	Very high	56 Å²	56	44 Å²	44	29%	0.287	27%	0.272	S	S	.	.	H	α-helix	trans	-69.9	-30.1	177.7	-57.9	176.8	0	0	0	110.5	D224 Y228 Q229 H230 M289 V292	D224-I226 PolarHBondContact O-N 3.43Å; D224-I226 WeakPolarHBondContact OD1-CB 3.48Å; D224-I226 PolarHBondContact OD1-N 2.96Å; I226-Y228 VanDerWaalsContact C-N 3.28Å; I226-Y228 PolarHBondContact O-N 3.12Å; I226-Q229 WeakPolarHBondContact O-CB 3.42Å; I226-Q229 PolarHBondContact O-N 2.88Å; I226-H230 PolarHBondContact O-CD2 3.35Å; I226-H230 VanDerWaalsContact O-CD2 3.31Å; I226-H230 PolarHBondContact O-N 2.84Å; I226-M289 HydrophobicContact CG2-CE 3.77Å; I226-V292 HydrophobicContact CD1-CB 4.44Å; I226-V292 HydrophobicContact CG2-CG2 4.22Å
227	L	98.4	Very high	97.6	Very high	74 Å²	74	40.3 Å²	40.3	39%	0.387	26%	0.256	S	S	.	.	H	α-helix	trans	-57.4	-43.6	170.9	177.3	62.6	0	0	0	111.1	F217 D224 P225 Q229 H230 L231	F217-L227 HydrophobicContact CD1-CB 4.41Å; F217-L227 HydrophobicContact CE1-CB 4.33Å; F217-L227 HydrophobicContact CE1-CD2 4.16Å; F217-L227 HydrophobicContact CE1-CG 4.11Å; D224-L227 HydrophobicContact CB-CB 4.32Å; D224-L227 VanDerWaalsContact O-CB 3.24Å; D224-L227 WeakPolarHBondContact O-CB 3.25Å; D224-L227 PolarHBondContact O-N 3.43Å; P225-L227 VanDerWaalsContact C-N 3.3Å; L227-Q229 VanDerWaalsContact C-N 3.29Å; L227-Q229 PolarHBondContact O-N 2.91Å; L227-H230 PolarHBondContact O-N 3.45Å; L227-L231 HydrophobicContact CD1-CG 4.42Å; L227-L231 HydrophobicContact CG-CD1 4.26Å; L227-L231 WeakPolarHBondContact O-CG 3.24Å; L227-L231 PolarHBondContact O-N 3.42Å
228	Y	98.6	Very high	97.6	Very high	2 Å²	2	40.2 Å²	40.2	1%	0.008	26%	0.256	C	S	.	.	H	α-helix	trans	-59.7	-42.2	175.4	-176.3	-81.5	0	0	0	111	T124 V125 Y126 P127 L206 F217 P225 I226 H230 L231 F232	T124-Y228 WeakPolarHBondContact O-CE1 3.47Å; T124-Y228 PolarHBondContact O-OH 2.7Å; V125-Y228 PolarHBondContact O-OH 3.47Å; Y126-Y228 AromaticContact CD1-CD1 3.57Å; Y126-Y228 HydrophobicContact CD1-CD1 3.57Å; Y126-Y228 AromaticContact CD1-CE1 3.59Å; Y126-Y228 HydrophobicContact CD1-CE1 3.59Å; Y126-Y228 HydrophobicContact CE1-CD1 4.08Å; Y126-Y228 HydrophobicContact CE1-CE1 4.1Å; P127-Y228 VanDerWaalsContact CD-CG 3.41Å; P127-Y228 HydrophobicContact CG-CD1 4.45Å; P127-Y228 HydrophobicContact CG-CD2 4.15Å; P127-Y228 HydrophobicContact CG-CG 3.84Å; L206-Y228 HydrophobicContact CB-CE2 4.19Å; L206-Y228 HydrophobicContact CD2-CE2 3.97Å; F217-Y228 HydrophobicContact CD2-CD2 4.1Å; F217-Y228 HydrophobicContact CE1-CD2 4.24Å; F217-Y228 HydrophobicContact CE1-CG 4.47Å; F217-Y228 AromaticContact CE2-CD2 3.61Å; F217-Y228 HydrophobicContact CE2-CD2 3.61Å; F217-Y228 HydrophobicContact CE2-CE2 4.47Å; F217-Y228 HydrophobicContact CE2-CG 4.48Å; F217-Y228 AromaticContact CZ-CD2 3.69Å; F217-Y228 HydrophobicContact CZ-CD2 3.69Å; F217-Y228 HydrophobicContact CZ-CG 4.35Å; P225-Y228 WeakPolarHBondContact O-CB 3.27Å; P225-Y228 PolarHBondContact O-N 3.28Å; I226-Y228 VanDerWaalsContact C-N 3.28Å; I226-Y228 PolarHBondContact O-N 3.12Å; Y228-H230 VanDerWaalsContact C-N 3.34Å; Y228-H230 PolarHBondContact O-N 2.91Å; Y228-L231 PolarHBondContact O-N 3.26Å; Y228-F232 HydrophobicContact CD1-CB 4.16Å; Y228-F232 HydrophobicContact CE1-CB 3.81Å; Y228-F232 HydrophobicContact CE1-CD2 4.05Å; Y228-F232 HydrophobicContact CE1-CG 4.16Å; Y228-F232 VanDerWaalsContact O-CB 3.26Å; Y228-F232 WeakPolarHBondContact O-CB 3.04Å; Y228-F232 PolarHBondContact O-N 3.41Å
229	Q	98.5	Very high	97.6	Very high	36 Å²	36	36.6 Å²	36.6	17%	0.168	24%	0.236	C	C	.	.	H	α-helix	trans	-61.4	-41.7	177.6	-61.5	-166.2	33.6	0	0	112.2	Y126 P225 I226 L227 W233 M289	Y126-Q229 HydrophobicContact CD1-CG 4.21Å; Y126-Q229 HydrophobicContact CE1-CB 4.46Å; Y126-Q229 HydrophobicContact CE1-CG 3.83Å; Y126-Q229 HydrophobicContact CE2-CG 4.33Å; P225-Q229 PolarHBondContact O-N 2.95Å; I226-Q229 WeakPolarHBondContact O-CB 3.42Å; I226-Q229 PolarHBondContact O-N 2.88Å; L227-Q229 VanDerWaalsContact C-N 3.29Å; L227-Q229 PolarHBondContact O-N 2.91Å; Q229-W233 WeakPolarHBondContact O-CB 3.17Å; Q229-W233 VanDerWaalsContact O-CD1 3.23Å; Q229-W233 PolarHBondContact O-N 3.19Å; Q229-M289 HydrophobicContact CB-CE 3.58Å; Q229-M289 HydrophobicContact CB-CG 4.4Å; Q229-M289 HydrophobicContact CB-SD 4.02Å
230	H	98.6	Very high	97.6	Very high	68 Å²	68	34.1 Å²	34.1	32%	0.315	22%	0.219	S	C	.	.	H	α-helix	trans	-60.4	-49.5	174.4	-80.6	-78.9	0	0	0	111.7	I226 L227 Y228 W233 F234 W285 M289	I226-H230 PolarHBondContact O-CD2 3.35Å; I226-H230 VanDerWaalsContact O-CD2 3.31Å; I226-H230 PolarHBondContact O-N 2.84Å; L227-H230 PolarHBondContact O-N 3.45Å; Y228-H230 VanDerWaalsContact C-N 3.34Å; Y228-H230 PolarHBondContact O-N 2.91Å; H230-W233 PolarHBondContact O-N 3.01Å; H230-F234 WeakPolarHBondContact O-CB 3.33Å; H230-F234 PolarHBondContact O-N 2.9Å; H230-W285 AromaticContact ND1-NE1 3.49Å; H230-W285 PolarHBondContact ND1-NE1 3.45Å; H230-M289 VanDerWaalsContact CD2-CE 3.44Å; H230-M289 WeakPolarHBondContact CD2-CE 3.19Å; H230-M289 WeakPolarHBondContact NE2-CE 3.49Å
231	L	98.6	Very high	97.7	Very high	36 Å²	36	31 Å²	31	19%	0.188	19%	0.187	C	C	.	.	H	α-helix	trans	-61.7	-46.4	179.6	-66.3	173.9	0	0	0	111.4	V198 M205 F217 L227 Y228 F235	V198-L231 HydrophobicContact CG1-CB 4.32Å; V198-L231 HydrophobicContact CG1-CD2 3.88Å; M205-L231 HydrophobicContact SD-CD1 3.94Å; F217-L231 HydrophobicContact CE1-CD1 4.31Å; F217-L231 HydrophobicContact CZ-CD1 4.27Å; L227-L231 HydrophobicContact CD1-CG 4.42Å; L227-L231 HydrophobicContact CG-CD1 4.26Å; L227-L231 WeakPolarHBondContact O-CG 3.24Å; L227-L231 PolarHBondContact O-N 3.42Å; Y228-L231 PolarHBondContact O-N 3.26Å; L231-F235 PolarHBondContact O-N 3.39Å
232	F	98.7	Very high	97.8	Very high	7 Å²	7	29.2 Å²	29.2	3%	0.031	17%	0.168	C	C	.	.	H	α-helix	trans	-63.3	-47.9	-179.8	-175.8	-87.6	0	0	0	111.3	W123 T124 Y126 L199 Y228 F235 G236	W123-F232 HydrophobicContact CD2-CZ 4.32Å; W123-F232 HydrophobicContact CE3-CE1 4.48Å; W123-F232 AromaticContact CE3-CZ 3.74Å; W123-F232 HydrophobicContact CE3-CZ 3.74Å; W123-F232 AromaticContact CH2-CE1 3.92Å; W123-F232 HydrophobicContact CH2-CE1 3.92Å; W123-F232 AromaticContact CH2-CZ 3.92Å; W123-F232 HydrophobicContact CH2-CZ 3.92Å; W123-F232 HydrophobicContact CZ2-CE1 4.3Å; W123-F232 HydrophobicContact CZ2-CZ 4.47Å; W123-F232 HydrophobicContact CZ3-CE1 4.03Å; W123-F232 AromaticContact CZ3-CZ 3.53Å; W123-F232 HydrophobicContact CZ3-CZ 3.53Å; T124-F232 HydrophobicContact CG2-CD1 4.32Å; T124-F232 HydrophobicContact CG2-CE1 3.68Å; T124-F232 HydrophobicContact CG2-CZ 4.03Å; Y126-F232 HydrophobicContact CE1-CD1 4.44Å; L199-F232 HydrophobicContact CD1-CD2 3.94Å; L199-F232 HydrophobicContact CD1-CE2 4.1Å; Y228-F232 HydrophobicContact CD1-CB 4.16Å; Y228-F232 HydrophobicContact CE1-CB 3.81Å; Y228-F232 HydrophobicContact CE1-CD2 4.05Å; Y228-F232 HydrophobicContact CE1-CG 4.16Å; Y228-F232 VanDerWaalsContact O-CB 3.26Å; Y228-F232 WeakPolarHBondContact O-CB 3.04Å; Y228-F232 PolarHBondContact O-N 3.41Å; F232-F235 CarbonylContact O-C 3.57Å; F232-F235 WeakPolarHBondContact O-CB 3.41Å; F232-F235 PolarHBondContact O-N 3.46Å; F232-G236 WeakPolarHBondContact O-CA 3.32Å; F232-G236 PolarHBondContact O-N 2.88Å
233	W	98.6	Very high	97.7	Very high	10 Å²	10	26 Å²	26	4%	0.038	13%	0.134	C	C	.	.	H	α-helix	trans	-76.4	-29	-177.2	-73.2	126.7	0	0	0	113.6	W123 T124 Y126 Q229 H230 F235 G236 H237 W285 H288	W123-W233 HydrophobicContact CH2-CH2 4.38Å; W123-W233 HydrophobicContact CH2-CZ3 4.08Å; W123-W233 AromaticContact CZ2-CH2 3.78Å; W123-W233 HydrophobicContact CZ2-CH2 3.78Å; W123-W233 AromaticContact CZ2-CZ3 3.92Å; W123-W233 HydrophobicContact CZ2-CZ3 3.92Å; T124-W233 HydrophobicContact CG2-CH2 4.17Å; T124-W233 HydrophobicContact CG2-CZ2 3.99Å; Y126-W233 AromaticContact CZ-NE1 3.95Å; Y126-W233 VanDerWaalsContact OH-CZ2 3.31Å; Y126-W233 WeakPolarHBondContact OH-CZ2 3.23Å; Y126-W233 PolarHBondContact OH-NE1 3.18Å; Q229-W233 WeakPolarHBondContact O-CB 3.17Å; Q229-W233 VanDerWaalsContact O-CD1 3.23Å; Q229-W233 PolarHBondContact O-N 3.19Å; H230-W233 PolarHBondContact O-N 3.01Å; W233-F235 PolarHBondContact O-N 2.67Å; W233-G236 PolarHBondContact O-N 3.24Å; W233-H237 PolarHBondContact O-N 3.25Å; W233-W285 HydrophobicContact CB-CB 4.23Å; W233-W285 VanDerWaalsContact O-CB 3.26Å; W233-W285 WeakPolarHBondContact O-CB 3.37Å; W233-H288 HydrophobicContact CD2-CB 3.4Å; W233-H288 VanDerWaalsContact CD2-CB 3.4Å; W233-H288 AromaticContact CD2-CD2 3.54Å; W233-H288 AromaticContact CD2-CG 3.55Å; W233-H288 AromaticContact CE2-CG 3.74Å; W233-H288 HydrophobicContact CE3-CB 3.97Å; W233-H288 AromaticContact CE3-CD2 3.24Å; W233-H288 AromaticContact CE3-CG 3.55Å; W233-H288 AromaticContact CE3-NE2 3.63Å; W233-H288 HydrophobicContact CG-CB 3.67Å; W233-H288 HydrophobicContact CH2-CB 4.31Å; W233-H288 AromaticContact CH2-CG 4Å; W233-H288 AromaticContact CH2-ND1 3.9Å; W233-H288 HydrophobicContact CZ2-CB 3.78Å; W233-H288 AromaticContact CZ2-CG 3.99Å; W233-H288 HydrophobicContact CZ3-CB 4.38Å; W233-H288 AromaticContact CZ3-CD2 3.72Å; W233-H288 AromaticContact CZ3-CE1 3.81Å; W233-H288 AromaticContact CZ3-CG 3.78Å; W233-H288 AromaticContact CZ3-ND1 3.85Å; W233-H288 AromaticContact CZ3-NE2 3.72Å
234	F	98.4	Very high	97.7	Very high	60 Å²	60	25.8 Å²	25.8	26%	0.263	13%	0.129	S	C	.	.	H	α-helix	trans	-57.3	-34.3	170	-174.6	-87.2	0	0	0	111.3	V198 H230 P238 F282 W285	V198-F234 HydrophobicContact CB-CD1 3.99Å; V198-F234 HydrophobicContact CG1-CB 4.35Å; V198-F234 HydrophobicContact CG1-CD1 3.87Å; V198-F234 HydrophobicContact CG1-CG 4.45Å; V198-F234 HydrophobicContact CG2-CD1 3.69Å; V198-F234 HydrophobicContact CG2-CE1 3.79Å; H230-F234 WeakPolarHBondContact O-CB 3.33Å; H230-F234 PolarHBondContact O-N 2.9Å; F234-P238 WeakPolarHBondContact O-CD 3.48Å; F234-P238 WeakPolarHBondContact O-CG 3.08Å; F234-F282 AromaticContact CE1-CD1 3.97Å; F234-F282 HydrophobicContact CE1-CD1 3.97Å; F234-F282 HydrophobicContact CE1-CE1 4.13Å; F234-F282 HydrophobicContact CE2-CD1 4.34Å; F234-F282 AromaticContact CZ-CD1 3.75Å; F234-F282 HydrophobicContact CZ-CD1 3.75Å; F234-F282 HydrophobicContact CZ-CE1 4.33Å; F234-W285 HydrophobicContact CB-CG 4.36Å; F234-W285 HydrophobicContact CD2-CD2 4.04Å; F234-W285 AromaticContact CD2-CE3 3.98Å; F234-W285 HydrophobicContact CD2-CE3 3.98Å; F234-W285 HydrophobicContact CD2-CZ3 4.26Å; F234-W285 HydrophobicContact CE2-CE3 4.43Å; F234-W285 HydrophobicContact CE2-CZ3 4.42Å
235	F	98.1	Very high	97.7	Very high	0 Å²	0	22.2 Å²	22.2	0%	0	11%	0.11	C	C	.	.	H	α-helix	trans	-76.8	-49.6	165.3	154.5	-101.6	0	0	0	112.5	F64 L196 L199 L231 F232 W233 H237 P238 E239	F64-F235 HydrophobicContact CE1-CZ 4.02Å; F64-F235 HydrophobicContact CZ-CE1 4.22Å; F64-F235 AromaticContact CZ-CZ 3.92Å; F64-F235 HydrophobicContact CZ-CZ 3.92Å; L196-F235 HydrophobicContact CD2-CD2 4.12Å; L196-F235 HydrophobicContact CD2-CE2 3.52Å; L196-F235 HydrophobicContact CD2-CZ 4.3Å; L196-F235 HydrophobicContact CG-CE2 4.36Å; L199-F235 HydrophobicContact CB-CB 3.89Å; L199-F235 HydrophobicContact CB-CD1 3.86Å; L199-F235 HydrophobicContact CB-CD2 3.95Å; L199-F235 HydrophobicContact CB-CE1 4.42Å; L199-F235 HydrophobicContact CB-CG 3.59Å; L199-F235 HydrophobicContact CD1-CD1 3.78Å; L199-F235 HydrophobicContact CD1-CE1 4.11Å; L199-F235 HydrophobicContact CD1-CG 4.4Å; L199-F235 HydrophobicContact CD2-CD1 3.93Å; L199-F235 HydrophobicContact CD2-CD2 4.38Å; L199-F235 HydrophobicContact CD2-CE1 3.64Å; L199-F235 HydrophobicContact CD2-CE2 4.12Å; L199-F235 HydrophobicContact CD2-CG 4.29Å; L199-F235 HydrophobicContact CD2-CZ 3.74Å; L199-F235 HydrophobicContact CG-CD1 4.05Å; L199-F235 HydrophobicContact CG-CE1 4.26Å; L199-F235 HydrophobicContact CG-CG 4.29Å; L231-F235 PolarHBondContact O-N 3.39Å; F232-F235 CarbonylContact O-C 3.57Å; F232-F235 WeakPolarHBondContact O-CB 3.41Å; F232-F235 PolarHBondContact O-N 3.46Å; W233-F235 PolarHBondContact O-N 2.67Å; F235-H237 VanDerWaalsContact C-N 3.34Å; F235-H237 PolarHBondContact O-N 3.38Å; F235-P238 VanDerWaalsContact O-CD 3.25Å; F235-P238 WeakPolarHBondContact O-CD 3.37Å; F235-E239 HydrophobicContact CD2-CB 4.35Å; F235-E239 HydrophobicContact CE1-CB 4.14Å; F235-E239 HydrophobicContact CE1-CG 4.22Å; F235-E239 HydrophobicContact CE2-CB 3.76Å; F235-E239 HydrophobicContact CE2-CG 3.98Å; F235-E239 WeakPolarHBondContact CE2-OE2 3.17Å; F235-E239 HydrophobicContact CZ-CB 3.64Å; F235-E239 HydrophobicContact CZ-CG 3.53Å; F235-E239 WeakPolarHBondContact O-CB 3.46Å; F235-E239 PolarHBondContact O-N 2.86Å
236	G	96.9	Very high	97.8	Very high	0 Å²	0	21 Å²	21	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-66.4	-31.2	-164	0	0	0	0	0	114	F232 W233 E239 V240	F232-G236 WeakPolarHBondContact O-CA 3.32Å; F232-G236 PolarHBondContact O-N 2.88Å; W233-G236 PolarHBondContact O-N 3.24Å; G236-E239 WeakPolarHBondContact O-CB 3.49Å; G236-V240 PolarHBondContact O-N 3.37Å
237	H	97.6	Very high	97.8	Very high	10 Å²	10	18.3 Å²	18.3	5%	0.046	9%	0.088	C	C	.	.	H	α-helix	trans	-75.7	-46.3	175.9	-163.1	79.9	0	0	0	113.2	W233 F235 E239 V240 Y241 V284 W285 H287 H288	W233-H237 PolarHBondContact O-N 3.25Å; F235-H237 VanDerWaalsContact C-N 3.34Å; F235-H237 PolarHBondContact O-N 3.38Å; H237-E239 PolarHBondContact O-N 3.25Å; H237-V240 WeakPolarHBondContact O-CG2 3.36Å; H237-V240 PolarHBondContact O-N 2.91Å; H237-Y241 AromaticContact CD2-CD2 3.98Å; H237-Y241 AromaticContact CD2-CE2 3.37Å; H237-Y241 WeakPolarHBondContact CD2-CE2 3.32Å; H237-Y241 AromaticContact NE2-CD2 3.94Å; H237-Y241 AromaticContact NE2-CE2 2.97Å; H237-Y241 WeakPolarHBondContact NE2-CE2 2.99Å; H237-Y241 AromaticContact NE2-CZ 3.24Å; H237-Y241 PolarHBondContact NE2-OH 3.2Å; H237-Y241 PolarHBondContact O-N 2.88Å; H237-V284 WeakPolarHBondContact CD2-CG2 3.45Å; H237-V284 WeakPolarHBondContact NE2-CG2 3.23Å; H237-W285 HydrophobicContact CB-CB 4.16Å; H237-H287 AromaticContact CE1-CE1 3.02Å; H237-H287 PolarHBondContact CE1-CE1 3.22Å; H237-H287 AromaticContact CE1-NE2 3.23Å; H237-H287 PolarHBondContact CE1-NE2 3.32Å; H237-H287 AromaticContact CG-CE1 3.83Å; H237-H287 AromaticContact CG-NE2 3.88Å; H237-H287 AromaticContact ND1-CE1 3.06Å; H237-H287 PolarHBondContact ND1-CE1 3.4Å; H237-H287 AromaticContact ND1-NE2 2.89Å; H237-H287 PolarHBondContact ND1-NE2 3.33Å; H237-H287 AromaticContact NE2-CE1 3.66Å; H237-H288 AromaticContact ND1-NE2 3.31Å; H237-H288 PolarHBondContact ND1-NE2 3.4Å
238	P	98.1	Very high	97.8	Very high	0 Å²	0	14.9 Å²	14.9	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-53.1	-38.7	165.1	-30.5	36.7	0	0	0	113.6	F234 F235 V240 Y241 I242 G281 F282	F234-P238 WeakPolarHBondContact O-CD 3.48Å; F234-P238 WeakPolarHBondContact O-CG 3.08Å; F235-P238 VanDerWaalsContact O-CD 3.25Å; F235-P238 WeakPolarHBondContact O-CD 3.37Å; P238-V240 PolarHBondContact O-N 3.36Å; P238-Y241 WeakPolarHBondContact O-CA 3.4Å; P238-Y241 WeakPolarHBondContact O-CB 3.23Å; P238-Y241 PolarHBondContact O-N 3.49Å; P238-I242 WeakPolarHBondContact O-CG1 3.25Å; P238-I242 PolarHBondContact O-N 2.94Å; P238-G281 WeakPolarHBondContact CD-O 3.37Å; P238-F282 HydrophobicContact CB-CE1 4.08Å; P238-F282 HydrophobicContact CB-CZ 4.22Å; P238-F282 HydrophobicContact CG-CD1 3.65Å; P238-F282 HydrophobicContact CG-CE1 3.61Å; P238-F282 HydrophobicContact CG-CG 4.24Å; P238-F282 HydrophobicContact CG-CZ 4.18Å
239	E	97.3	Very high	97.7	Very high	1 Å²	1	14.8 Å²	14.8	1%	0.005	7%	0.07	C	C	.	.	H	α-helix	trans	-58.6	-44.9	177.4	-177.1	59.8	-156.1	0	0	112.1	M68 F235 G236 H237 Y241 I242 L243	M68-E239 WeakPolarHBondContact CE-OE1 3.3Å; F235-E239 HydrophobicContact CD2-CB 4.35Å; F235-E239 HydrophobicContact CE1-CB 4.14Å; F235-E239 HydrophobicContact CE1-CG 4.22Å; F235-E239 HydrophobicContact CE2-CB 3.76Å; F235-E239 HydrophobicContact CE2-CG 3.98Å; F235-E239 WeakPolarHBondContact CE2-OE2 3.17Å; F235-E239 HydrophobicContact CZ-CB 3.64Å; F235-E239 HydrophobicContact CZ-CG 3.53Å; F235-E239 WeakPolarHBondContact O-CB 3.46Å; F235-E239 PolarHBondContact O-N 2.86Å; G236-E239 WeakPolarHBondContact O-CB 3.49Å; H237-E239 PolarHBondContact O-N 3.25Å; E239-Y241 PolarHBondContact O-N 3.08Å; E239-Y241 VanDerWaalsContact O-N 3.16Å; E239-I242 VanDerWaalsContact O-CB 3.3Å; E239-I242 WeakPolarHBondContact O-CB 3.48Å; E239-I242 PolarHBondContact O-N 3.43Å; E239-L243 HydrophobicContact CG-CD1 4.44Å; E239-L243 VanDerWaalsContact O-CG 3.28Å; E239-L243 WeakPolarHBondContact O-CG 3.36Å; E239-L243 PolarHBondContact O-N 3.43Å
240	V	96	Very high	97.7	Very high	31 Å²	31	13.1 Å²	13.1	19%	0.188	6%	0.062	C	C	.	.	H	α-helix	trans	-64.4	-24.6	177.5	-58.4	0	0	0	0	112.9	G236 H237 P238 F374	G236-V240 PolarHBondContact O-N 3.37Å; H237-V240 WeakPolarHBondContact O-CG2 3.36Å; H237-V240 PolarHBondContact O-N 2.91Å; P238-V240 PolarHBondContact O-N 3.36Å; V240-F374 HydrophobicContact CB-CE2 4.39Å; V240-F374 HydrophobicContact CG1-CE2 3.61Å; V240-F374 HydrophobicContact CG1-CZ 4.23Å
241	Y	97	Very high	97.7	Very high	31 Å²	31	9.9 Å²	9.9	12%	0.122	5%	0.047	C	C	.	.	H	α-helix	trans	-77.9	-37.8	170.3	-69.7	-49.7	0	0	0	113.6	H237 P238 E239 L243 I244 L245 I277 I309	H237-Y241 AromaticContact CD2-CD2 3.98Å; H237-Y241 AromaticContact CD2-CE2 3.37Å; H237-Y241 WeakPolarHBondContact CD2-CE2 3.32Å; H237-Y241 AromaticContact NE2-CD2 3.94Å; H237-Y241 AromaticContact NE2-CE2 2.97Å; H237-Y241 WeakPolarHBondContact NE2-CE2 2.99Å; H237-Y241 AromaticContact NE2-CZ 3.24Å; H237-Y241 PolarHBondContact NE2-OH 3.2Å; H237-Y241 PolarHBondContact O-N 2.88Å; P238-Y241 WeakPolarHBondContact O-CA 3.4Å; P238-Y241 WeakPolarHBondContact O-CB 3.23Å; P238-Y241 PolarHBondContact O-N 3.49Å; E239-Y241 PolarHBondContact O-N 3.08Å; E239-Y241 VanDerWaalsContact O-N 3.16Å; Y241-L243 PolarHBondContact O-N 3.24Å; Y241-I244 HydrophobicContact CD1-CG2 4.15Å; Y241-I244 PolarHBondContact O-N 3.2Å; Y241-L245 WeakPolarHBondContact O-CB 3.29Å; Y241-L245 VanDerWaalsContact O-CG 3.28Å; Y241-L245 WeakPolarHBondContact O-CG 3.35Å; Y241-L245 PolarHBondContact O-N 3.46Å; Y241-I277 HydrophobicContact CD1-CG2 3.46Å; Y241-I277 VanDerWaalsContact CD1-CG2 3.46Å; Y241-I277 HydrophobicContact CD2-CG2 4.24Å; Y241-I277 HydrophobicContact CE1-CG2 3.74Å; Y241-I277 HydrophobicContact CE2-CG2 4.42Å; Y241-I277 HydrophobicContact CG-CG2 3.8Å; Y241-I309 HydrophobicContact CE1-CG2 4.37Å; Y241-I309 HydrophobicContact CE2-CD1 4.13Å; Y241-I309 WeakPolarHBondContact OH-CD1 3.49Å; Y241-I309 WeakPolarHBondContact OH-CG2 3.36Å
242	I	96.7	Very high	97.7	Very high	3 Å²	3	8.2 Å²	8.2	2%	0.015	4%	0.039	C	C	.	.	H	α-helix	trans	-52.8	-40.3	170.5	-73.5	158.1	0	0	0	109.9	M68 T188 L191 L192 P238 E239 I244 P246	M68-I242 HydrophobicContact CG-CG2 4.48Å; M68-I242 HydrophobicContact SD-CG2 4.44Å; T188-I242 HydrophobicContact CG2-CB 3.91Å; T188-I242 HydrophobicContact CG2-CG1 4Å; T188-I242 HydrophobicContact CG2-CG2 3.59Å; L191-I242 HydrophobicContact CB-CD1 3.74Å; L191-I242 HydrophobicContact CB-CG1 3.54Å; L191-I242 HydrophobicContact CD1-CG1 4.01Å; L191-I242 HydrophobicContact CG-CG1 4.41Å; L192-I242 HydrophobicContact CB-CD1 4.45Å; L192-I242 HydrophobicContact CD1-CG2 4.32Å; L192-I242 HydrophobicContact CD2-CD1 3.73Å; L192-I242 HydrophobicContact CD2-CG1 4.36Å; L192-I242 HydrophobicContact CD2-CG2 3.81Å; L192-I242 HydrophobicContact CG-CD1 3.79Å; L192-I242 HydrophobicContact CG-CG1 4.09Å; L192-I242 HydrophobicContact CG-CG2 3.96Å; P238-I242 WeakPolarHBondContact O-CG1 3.25Å; P238-I242 PolarHBondContact O-N 2.94Å; E239-I242 VanDerWaalsContact O-CB 3.3Å; E239-I242 WeakPolarHBondContact O-CB 3.48Å; E239-I242 PolarHBondContact O-N 3.43Å; I242-I244 PolarHBondContact O-N 2.83Å; I242-P246 WeakPolarHBondContact O-CD 3.34Å
243	L	94.8	Very high	97.5	Very high	5 Å²	5	8.7 Å²	8.7	3%	0.026	4%	0.041	C	C	.	.	H	α-helix	trans	-71.4	-23.7	179.4	-60.1	169.5	0	0	0	113.7	I63 V67 M68 M71 E239 Y241 L378	I63-L243 HydrophobicContact CG1-CD1 4.43Å; I63-L243 HydrophobicContact CG2-CD1 3.86Å; I63-L243 HydrophobicContact CG2-CD2 4.17Å; V67-L243 HydrophobicContact CB-CD2 4.15Å; V67-L243 HydrophobicContact CG1-CB 4.29Å; V67-L243 HydrophobicContact CG1-CD2 3.61Å; V67-L243 HydrophobicContact CG1-CG 4.49Å; M68-L243 HydrophobicContact CG-CD2 3.67Å; M71-L243 WeakPolarHBondContact CE-O 3.43Å; E239-L243 HydrophobicContact CG-CD1 4.44Å; E239-L243 VanDerWaalsContact O-CG 3.28Å; E239-L243 WeakPolarHBondContact O-CG 3.36Å; E239-L243 PolarHBondContact O-N 3.43Å; Y241-L243 PolarHBondContact O-N 3.24Å; L243-L378 HydrophobicContact CB-CD1 4.03Å; L243-L378 HydrophobicContact CD1-CD1 3.46Å; L243-L378 VanDerWaalsContact CD1-CD1 3.46Å; L243-L378 HydrophobicContact CG-CD1 4.31Å
244	I	97.6	Very high	97.4	Very high	10 Å²	10	8.2 Å²	8.2	5%	0.051	4%	0.039	C	C	.	.	H	α-helix	trans	-110.1	-27.4	-174.1	-162	62.4	0	0	0	114.4	Y241 I242 G247 F248 F341 F345	Y241-I244 HydrophobicContact CD1-CG2 4.15Å; Y241-I244 PolarHBondContact O-N 3.2Å; I242-I244 PolarHBondContact O-N 2.83Å; I244-G247 CarbonylContact O-C 3.57Å; I244-G247 VanDerWaalsContact O-CA 3.31Å; I244-G247 WeakPolarHBondContact O-CA 3.07Å; I244-G247 PolarHBondContact O-N 3.42Å; I244-F248 HydrophobicContact CB-CZ 4.45Å; I244-F248 HydrophobicContact CD1-CE1 4.36Å; I244-F248 HydrophobicContact CG1-CD1 4.12Å; I244-F248 HydrophobicContact CG1-CE1 3.55Å; I244-F248 HydrophobicContact CG1-CE2 4.36Å; I244-F248 HydrophobicContact CG1-CZ 3.68Å; I244-F248 HydrophobicContact CG2-CE2 3.95Å; I244-F248 HydrophobicContact CG2-CZ 3.91Å; I244-F248 PolarHBondContact O-N 2.93Å; I244-F341 HydrophobicContact CD1-CE2 3.9Å; I244-F341 HydrophobicContact CD1-CZ 4.23Å; I244-F345 HydrophobicContact CD1-CD2 4.2Å; I244-F345 HydrophobicContact CD1-CE2 4.02Å; I244-F345 HydrophobicContact CG1-CD2 4.38Å; I244-F345 HydrophobicContact CG1-CE2 3.74Å; I244-F345 HydrophobicContact CG1-CZ 4.31Å
245	L	98.2	Very high	97.3	Very high	0 Å²	0	5.6 Å²	5.6	0%	0	3%	0.028	C	C	.	.	H	α-helix	trans	-56.8	-48.3	-177.3	-78.5	168.7	0	0	0	112.5	S184 I187 T188 L191 Y241 G247 F248 G249 M274 I277	S184-L245 WeakPolarHBondContact CB-O 3.11Å; I187-L245 HydrophobicContact CB-CD1 4.42Å; I187-L245 HydrophobicContact CG2-CD1 3.73Å; T188-L245 WeakPolarHBondContact OG1-CB 3.4Å; L191-L245 HydrophobicContact CD1-CD1 3.66Å; Y241-L245 WeakPolarHBondContact O-CB 3.29Å; Y241-L245 VanDerWaalsContact O-CG 3.28Å; Y241-L245 WeakPolarHBondContact O-CG 3.35Å; Y241-L245 PolarHBondContact O-N 3.46Å; L245-G247 PolarHBondContact O-N 3.49Å; L245-F248 HydrophobicContact CD2-CD2 4.02Å; L245-F248 HydrophobicContact CD2-CE2 4.36Å; L245-F248 VanDerWaalsContact O-CB 3.32Å; L245-F248 WeakPolarHBondContact O-CB 3.27Å; L245-F248 PolarHBondContact O-N 3.47Å; L245-G249 PolarHBondContact O-N 3.07Å; L245-G249 VanDerWaalsContact O-N 3.1Å; L245-M274 HydrophobicContact CD2-CB 4.25Å; L245-M274 HydrophobicContact CD2-CG 4.2Å; L245-I277 HydrophobicContact CD2-CG2 4.26Å
246	P	98.4	Very high	97.1	Very high	0 Å²	0	6.3 Å²	6.3	0%	0	3%	0.032	C	C	.	.	H	α-helix	trans	-60.7	-35.8	174.9	-22.6	35.3	0	0	0	112.2	M71 I72 F181 S184 T188 I242 F248 G249 M250	M71-P246 HydrophobicContact CB-CB 4.14Å; M71-P246 HydrophobicContact CB-CG 4.47Å; M71-P246 HydrophobicContact SD-CB 4.02Å; I72-P246 HydrophobicContact CD1-CB 4.32Å; I72-P246 HydrophobicContact CD1-CG 3.44Å; I72-P246 VanDerWaalsContact CD1-CG 3.44Å; I72-P246 HydrophobicContact CG1-CG 4.17Å; F181-P246 HydrophobicContact CE2-CB 4.26Å; S184-P246 WeakPolarHBondContact OG-CA 3.19Å; T188-P246 HydrophobicContact CG2-CG 4.3Å; I242-P246 WeakPolarHBondContact O-CD 3.34Å; P246-F248 VanDerWaalsContact C-N 3.33Å; P246-F248 PolarHBondContact O-N 3.19Å; P246-G249 WeakPolarHBondContact O-CA 3.29Å; P246-G249 PolarHBondContact O-N 3.45Å; P246-G249 VanDerWaalsContact O-N 3.08Å; P246-M250 WeakPolarHBondContact O-CG 3.14Å; P246-M250 PolarHBondContact O-N 2.96Å
247	G	98.1	Very high	96.9	Very high	0 Å²	0	8.1 Å²	8.1	0%	0	4%	0.039	C	C	.	.	H	α-helix	trans	-55.8	-47.3	171.9	0	0	0	0	0	111.8	I244 L245 G249 M250 I251 A385	I244-G247 CarbonylContact O-C 3.57Å; I244-G247 VanDerWaalsContact O-CA 3.31Å; I244-G247 WeakPolarHBondContact O-CA 3.07Å; I244-G247 PolarHBondContact O-N 3.42Å; L245-G247 PolarHBondContact O-N 3.49Å; G247-G249 VanDerWaalsContact C-N 3.29Å; G247-G249 PolarHBondContact O-N 2.76Å; G247-M250 PolarHBondContact O-N 3.35Å; G247-I251 VanDerWaalsContact O-CG1 3.29Å; G247-I251 WeakPolarHBondContact O-CG1 3.25Å; G247-I251 PolarHBondContact O-N 3.04Å; G247-A385 VanDerWaalsContact CA-CB 3.46Å
248	F	98.4	Very high	96.6	Very high	3 Å²	3	9.4 Å²	9.4	1%	0.013	4%	0.044	C	C	.	.	H	α-helix	trans	-60.2	-38.2	174.1	-59.2	-29.1	0	0	0	113.3	I244 L245 P246 S252 I277 K316 W320 F341 F345	I244-F248 HydrophobicContact CB-CZ 4.45Å; I244-F248 HydrophobicContact CD1-CE1 4.36Å; I244-F248 HydrophobicContact CG1-CD1 4.12Å; I244-F248 HydrophobicContact CG1-CE1 3.55Å; I244-F248 HydrophobicContact CG1-CE2 4.36Å; I244-F248 HydrophobicContact CG1-CZ 3.68Å; I244-F248 HydrophobicContact CG2-CE2 3.95Å; I244-F248 HydrophobicContact CG2-CZ 3.91Å; I244-F248 PolarHBondContact O-N 2.93Å; L245-F248 HydrophobicContact CD2-CD2 4.02Å; L245-F248 HydrophobicContact CD2-CE2 4.36Å; L245-F248 VanDerWaalsContact O-CB 3.32Å; L245-F248 WeakPolarHBondContact O-CB 3.27Å; L245-F248 PolarHBondContact O-N 3.47Å; P246-F248 VanDerWaalsContact C-N 3.33Å; P246-F248 PolarHBondContact O-N 3.19Å; F248-S252 WeakPolarHBondContact O-CB 3.24Å; F248-S252 PolarHBondContact O-N 2.88Å; F248-S252 VanDerWaalsContact O-N 3.07Å; F248-S252 PolarHBondContact O-OG 2.64Å; F248-I277 HydrophobicContact CE2-CD1 4.16Å; F248-K316 VanDerWaalsContact CB-CE 3.41Å; F248-K316 VanDerWaalsContact CB-NZ 3.27Å; F248-K316 HydrophobicContact CD2-CD 4.11Å; F248-K316 HydrophobicContact CE2-CD 4.43Å; F248-K316 VanDerWaalsContact CG-CE 3.43Å; F248-W320 HydrophobicContact CB-CH2 4.09Å; F248-W320 HydrophobicContact CB-CZ2 3.89Å; F248-W320 AromaticContact CD1-CH2 3.46Å; F248-W320 HydrophobicContact CD1-CH2 3.46Å; F248-W320 VanDerWaalsContact CD1-CH2 3.46Å; F248-W320 HydrophobicContact CD1-CZ2 4.12Å; F248-W320 HydrophobicContact CD1-CZ3 4.46Å; F248-W320 HydrophobicContact CE1-CH2 4.04Å; F248-W320 AromaticContact CG-CH2 3.96Å; F248-W320 HydrophobicContact CG-CH2 3.96Å; F248-W320 HydrophobicContact CG-CZ2 4.28Å; F248-F341 HydrophobicContact CD1-CE1 4.17Å; F248-F341 AromaticContact CD1-CZ 3.64Å; F248-F341 HydrophobicContact CD1-CZ 3.64Å; F248-F341 HydrophobicContact CE1-CE1 4.4Å; F248-F341 AromaticContact CE1-CZ 3.78Å; F248-F341 HydrophobicContact CE1-CZ 3.78Å; F248-F345 HydrophobicContact CE1-CD1 4.25Å; F248-F345 AromaticContact CE1-CE1 3.68Å; F248-F345 HydrophobicContact CE1-CE1 3.68Å; F248-F345 HydrophobicContact CE1-CE2 4.04Å; F248-F345 AromaticContact CE1-CZ 3.58Å; F248-F345 HydrophobicContact CE1-CZ 3.58Å; F248-F345 AromaticContact CZ-CE1 3.83Å; F248-F345 HydrophobicContact CZ-CE1 3.83Å; F248-F345 HydrophobicContact CZ-CE2 4.19Å; F248-F345 AromaticContact CZ-CZ 3.48Å; F248-F345 HydrophobicContact CZ-CZ 3.48Å; F248-F345 VanDerWaalsContact CZ-CZ 3.48Å
249	G	98.1	Very high	96.3	Very high	0 Å²	0	9.9 Å²	9.9	0%	0	5%	0.047	C	C	.	.	H	α-helix	trans	-58.7	-52.2	172.9	0	0	0	0	0	111.4	L245 P246 G247 I251 S252 H253	L245-G249 PolarHBondContact O-N 3.07Å; L245-G249 VanDerWaalsContact O-N 3.1Å; P246-G249 WeakPolarHBondContact O-CA 3.29Å; P246-G249 PolarHBondContact O-N 3.45Å; P246-G249 VanDerWaalsContact O-N 3.08Å; G247-G249 VanDerWaalsContact C-N 3.29Å; G247-G249 PolarHBondContact O-N 2.76Å; G249-I251 PolarHBondContact O-N 2.82Å; G249-S252 WeakPolarHBondContact O-CB 3.18Å; G249-S252 PolarHBondContact O-N 2.86Å; G249-H253 PolarHBondContact O-CD2 3.06Å; G249-H253 PolarHBondContact O-N 3.41Å; G249-H253 VanDerWaalsContact O-N 3.12Å
250	M	98.4	Very high	95.9	Very high	0 Å²	0	12.8 Å²	12.8	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-59.9	-47.5	-179.6	-67.3	-171.4	-76	0	0	112.4	M71 F75 F181 P246 G247 S252 H253 I254 A385 W393	M71-M250 HydrophobicContact CG-CE 3.79Å; M71-M250 HydrophobicContact SD-CE 3.58Å; M71-M250 VanDerWaalsContact SD-CE 3.58Å; F75-M250 HydrophobicContact CB-SD 4.46Å; F75-M250 HydrophobicContact CD1-SD 4.22Å; F75-M250 HydrophobicContact CD2-CE 4.44Å; F75-M250 HydrophobicContact CD2-SD 3.72Å; F75-M250 HydrophobicContact CE1-SD 4.41Å; F75-M250 HydrophobicContact CE2-SD 3.92Å; F75-M250 HydrophobicContact CG-SD 3.88Å; F75-M250 HydrophobicContact CZ-SD 4.27Å; F181-M250 HydrophobicContact CD2-CG 3.72Å; F181-M250 HydrophobicContact CE2-CG 3.62Å; F181-M250 HydrophobicContact CE2-SD 4.43Å; P246-M250 WeakPolarHBondContact O-CG 3.14Å; P246-M250 PolarHBondContact O-N 2.96Å; G247-M250 PolarHBondContact O-N 3.35Å; M250-S252 VanDerWaalsContact C-N 3.27Å; M250-S252 PolarHBondContact O-N 2.68Å; M250-H253 PolarHBondContact O-N 3.18Å; M250-H253 VanDerWaalsContact O-N 3.17Å; M250-I254 WeakPolarHBondContact O-CG1 3.45Å; M250-I254 PolarHBondContact O-N 3.35Å; M250-A385 HydrophobicContact CE-CB 3.94Å; M250-W393 HydrophobicContact CB-CH2 4.14Å; M250-W393 HydrophobicContact CB-CZ3 3.95Å; M250-W393 HydrophobicContact CG-CH2 4.01Å; M250-W393 HydrophobicContact CG-CZ3 3.66Å; M250-W393 HydrophobicContact SD-CZ3 4.04Å
251	I	98.4	Very high	95.5	Very high	0 Å²	0	14.6 Å²	14.6	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-61.1	-38.4	178	-64.4	-55.7	0	0	0	111.3	G247 G249 H253 I254 V255 W320 A338 F341 I342 A385	G247-I251 VanDerWaalsContact O-CG1 3.29Å; G247-I251 WeakPolarHBondContact O-CG1 3.25Å; G247-I251 PolarHBondContact O-N 3.04Å; G249-I251 PolarHBondContact O-N 2.82Å; I251-H253 VanDerWaalsContact C-N 3.35Å; I251-H253 PolarHBondContact O-N 2.85Å; I251-I254 HydrophobicContact CD1-CD1 4.41Å; I251-I254 PolarHBondContact O-N 3.32Å; I251-V255 HydrophobicContact CG2-CG2 4.08Å; I251-V255 VanDerWaalsContact O-CB 3.29Å; I251-V255 WeakPolarHBondContact O-CB 3.28Å; I251-V255 VanDerWaalsContact O-CG2 3.26Å; I251-V255 WeakPolarHBondContact O-CG2 3.43Å; I251-V255 PolarHBondContact O-N 2.93Å; I251-W320 HydrophobicContact CB-CZ2 4.47Å; I251-W320 HydrophobicContact CG2-CD2 4.09Å; I251-W320 HydrophobicContact CG2-CG 4.39Å; I251-W320 HydrophobicContact CG2-CZ2 4.31Å; I251-A338 HydrophobicContact CD1-CB 4.03Å; I251-A338 HydrophobicContact CG2-CB 4.44Å; I251-F341 HydrophobicContact CB-CD1 4.24Å; I251-F341 HydrophobicContact CB-CE1 4.34Å; I251-F341 HydrophobicContact CD1-CB 3.93Å; I251-F341 HydrophobicContact CD1-CD1 4.12Å; I251-F341 HydrophobicContact CD1-CD2 4.37Å; I251-F341 HydrophobicContact CD1-CG 3.88Å; I251-F341 HydrophobicContact CG1-CB 4.31Å; I251-F341 HydrophobicContact CG1-CD1 3.56Å; I251-F341 HydrophobicContact CG1-CD2 4.08Å; I251-F341 HydrophobicContact CG1-CE1 3.84Å; I251-F341 HydrophobicContact CG1-CE2 4.3Å; I251-F341 HydrophobicContact CG1-CG 3.71Å; I251-F341 HydrophobicContact CG1-CZ 4.21Å; I251-F341 HydrophobicContact CG2-CD1 3.94Å; I251-F341 HydrophobicContact CG2-CE1 4.26Å; I251-I342 HydrophobicContact CG2-CD1 4.46Å; I251-I342 HydrophobicContact CG2-CG1 4.31Å; I251-A385 HydrophobicContact CD1-CB 4.22Å; I251-A385 HydrophobicContact CG1-CB 4.12Å
252	S	97.5	Very high	95	Very high	2 Å²	2	21.4 Å²	21.4	1%	0.014	11%	0.113	C	C	.	.	H	α-helix	trans	-63.2	-40.7	177	-53.6	0	0	0	0	112.4	F248 G249 M250 T256 M270 W320	F248-S252 WeakPolarHBondContact O-CB 3.24Å; F248-S252 PolarHBondContact O-N 2.88Å; F248-S252 VanDerWaalsContact O-N 3.07Å; F248-S252 PolarHBondContact O-OG 2.64Å; G249-S252 WeakPolarHBondContact O-CB 3.18Å; G249-S252 PolarHBondContact O-N 2.86Å; M250-S252 VanDerWaalsContact C-N 3.27Å; M250-S252 PolarHBondContact O-N 2.68Å; S252-T256 VanDerWaalsContact O-CB 3.27Å; S252-T256 WeakPolarHBondContact O-CB 3.38Å; S252-T256 PolarHBondContact O-N 3.49Å; S252-T256 VanDerWaalsContact O-N 3.08Å; S252-T256 PolarHBondContact O-OG1 3.35Å; S252-M270 VanDerWaalsContact OG-CE 3.26Å; S252-M270 WeakPolarHBondContact OG-CE 3.29Å; S252-W320 PolarHBondContact OG-NE1 3.29Å
253	H	95.6	Very high	94.6	Very high	17 Å²	17	27.2 Å²	27.2	8%	0.079	14%	0.14	C	C	.	.	H	α-helix	trans	-65.4	-48.6	174.9	-85	-101.5	0	0	0	111.8	P179 F181 G249 M250 I251 V255 T256 Y257 W393	P179-H253 VanDerWaalsContact CB-CE1 3.43Å; P179-H253 WeakPolarHBondContact CB-CE1 3.26Å; P179-H253 VanDerWaalsContact CB-NE2 3.34Å; P179-H253 WeakPolarHBondContact CB-NE2 3.29Å; F181-H253 WeakPolarHBondContact CB-NE2 3.4Å; F181-H253 PolarHBondContact N-NE2 3.13Å; G249-H253 PolarHBondContact O-CD2 3.06Å; G249-H253 PolarHBondContact O-N 3.41Å; G249-H253 VanDerWaalsContact O-N 3.12Å; M250-H253 PolarHBondContact O-N 3.18Å; M250-H253 VanDerWaalsContact O-N 3.17Å; I251-H253 VanDerWaalsContact C-N 3.35Å; I251-H253 PolarHBondContact O-N 2.85Å; H253-V255 PolarHBondContact O-N 3.47Å; H253-T256 PolarHBondContact O-N 2.94Å; H253-Y257 VanDerWaalsContact O-CB 3.24Å; H253-Y257 WeakPolarHBondContact O-CB 3.29Å; H253-Y257 PolarHBondContact O-N 3.47Å; H253-W393 HydrophobicContact CB-CH2 4.05Å; H253-W393 HydrophobicContact CB-CZ2 3.97Å
254	I	95.8	Very high	94.6	Very high	0 Å²	0	27.5 Å²	27.5	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-60.2	-49.8	-179.8	-64.8	164	0	0	0	110.5	M250 I251 T256 Y257 Y258 A334 A338 H392	M250-I254 WeakPolarHBondContact O-CG1 3.45Å; M250-I254 PolarHBondContact O-N 3.35Å; I251-I254 HydrophobicContact CD1-CD1 4.41Å; I251-I254 PolarHBondContact O-N 3.32Å; I254-T256 VanDerWaalsContact C-N 3.32Å; I254-T256 PolarHBondContact O-N 3.44Å; I254-Y257 PolarHBondContact O-N 3.39Å; I254-Y258 HydrophobicContact CG2-CD2 3.79Å; I254-Y258 HydrophobicContact CG2-CE2 4.06Å; I254-Y258 VanDerWaalsContact O-CD2 3.3Å; I254-Y258 WeakPolarHBondContact O-CD2 3.41Å; I254-Y258 PolarHBondContact O-N 3.16Å; I254-A334 HydrophobicContact CG2-CB 4.06Å; I254-A338 HydrophobicContact CG2-CB 3.9Å; I254-H392 HydrophobicContact CD1-CB 4.43Å; I254-H392 HydrophobicContact CG1-CB 4.04Å
255	V	95.8	Very high	94.5	Very high	4 Å²	4	33.2 Å²	33.2	2%	0.024	17%	0.167	C	C	.	.	H	α-helix	trans	-59.5	-44.2	179.7	164.8	0	0	0	0	110.9	I251 H253 S259 T323 L324 A338 I342	I251-V255 HydrophobicContact CG2-CG2 4.08Å; I251-V255 VanDerWaalsContact O-CB 3.29Å; I251-V255 WeakPolarHBondContact O-CB 3.28Å; I251-V255 VanDerWaalsContact O-CG2 3.26Å; I251-V255 WeakPolarHBondContact O-CG2 3.43Å; I251-V255 PolarHBondContact O-N 2.93Å; H253-V255 PolarHBondContact O-N 3.47Å; V255-S259 WeakPolarHBondContact O-CB 3.14Å; V255-S259 PolarHBondContact O-N 3.32Å; V255-S259 VanDerWaalsContact O-N 3.13Å; V255-S259 PolarHBondContact O-OG 2.64Å; V255-T323 HydrophobicContact CG1-CG2 3.72Å; V255-L324 HydrophobicContact CB-CD2 4.46Å; V255-L324 HydrophobicContact CG1-CD1 4.46Å; V255-L324 HydrophobicContact CG1-CD2 3.77Å; V255-L324 HydrophobicContact CG1-CG 3.75Å; V255-L324 HydrophobicContact CG2-CD2 4.35Å; V255-A338 HydrophobicContact CG2-CB 4.12Å; V255-I342 HydrophobicContact CG2-CD1 4.23Å
256	T	93.5	Very high	94.4	Very high	15 Å²	15	35 Å²	35	9%	0.092	19%	0.185	C	C	.	.	H	α-helix	trans	-66.8	-48.1	-179.7	-56.6	0	0	0	0	111.4	S252 H253 I254 S259 G260 K261	S252-T256 VanDerWaalsContact O-CB 3.27Å; S252-T256 WeakPolarHBondContact O-CB 3.38Å; S252-T256 PolarHBondContact O-N 3.49Å; S252-T256 VanDerWaalsContact O-N 3.08Å; S252-T256 PolarHBondContact O-OG1 3.35Å; H253-T256 PolarHBondContact O-N 2.94Å; I254-T256 VanDerWaalsContact C-N 3.32Å; I254-T256 PolarHBondContact O-N 3.44Å; T256-S259 PolarHBondContact O-N 3.08Å; T256-G260 PolarHBondContact O-N 3.49Å; T256-K261 HydrophobicContact CG2-CB 4.47Å; T256-K261 WeakPolarHBondContact CG2-O 3.31Å; T256-K261 PolarHBondContact O-N 2.91Å
257	Y	92.7	Very high	94.3	Very high	39 Å²	39	36.4 Å²	36.4	15%	0.153	19%	0.191	C	C	.	.	H	α-helix	trans	-56.9	-53.9	-179.4	-175.7	-91.5	0	0	0	111.8	H253 I254 S259 G260 H392 E483	H253-Y257 VanDerWaalsContact O-CB 3.24Å; H253-Y257 WeakPolarHBondContact O-CB 3.29Å; H253-Y257 PolarHBondContact O-N 3.47Å; I254-Y257 PolarHBondContact O-N 3.39Å; Y257-S259 VanDerWaalsContact C-N 3.3Å; Y257-S259 PolarHBondContact O-N 3.5Å; Y257-G260 PolarHBondContact O-N 3.04Å; Y257-G260 VanDerWaalsContact O-N 3.14Å; Y257-H392 AromaticContact CD1-CE1 3.67Å; Y257-H392 AromaticContact CG-CE1 3.65Å; Y257-E483 WeakPolarHBondContact CE2-O 3.45Å; Y257-E483 PolarHBondContact OH-O 3.33Å
258	Y	92.5	Very high	94.2	Very high	37 Å²	37	40 Å²	40	15%	0.145	21%	0.209	C	C	.	.	H	α-helix	trans	-78.5	-12.9	-176.5	-71.9	-77.4	0	0	0	114.3	I254 G260 K330 S332 A334 V335 H392	I254-Y258 HydrophobicContact CG2-CD2 3.79Å; I254-Y258 HydrophobicContact CG2-CE2 4.06Å; I254-Y258 VanDerWaalsContact O-CD2 3.3Å; I254-Y258 WeakPolarHBondContact O-CD2 3.41Å; I254-Y258 PolarHBondContact O-N 3.16Å; Y258-G260 VanDerWaalsContact C-N 3.31Å; Y258-K330 HydrophobicContact CD1-CB 4.31Å; Y258-S332 WeakPolarHBondContact CD1-OG 3.48Å; Y258-S332 WeakPolarHBondContact CE1-OG 3.23Å; Y258-S332 VanDerWaalsContact CZ-OG 3.22Å; Y258-A334 HydrophobicContact CD2-CB 4.42Å; Y258-A334 HydrophobicContact CE2-CB 3.57Å; Y258-V335 HydrophobicContact CD1-CG2 3.96Å; Y258-V335 HydrophobicContact CD2-CG2 3.66Å; Y258-V335 HydrophobicContact CG-CG2 3.34Å; Y258-H392 AromaticContact CE2-ND1 3.7Å
259	S	91.8	Very high	94.2	Very high	10 Å²	10	41.4 Å²	41.4	7%	0.07	22%	0.224	C	C	.	.	T	Hydrogen-bonded Turn	trans	-82.7	-9.2	169.1	-58.9	0	0	0	0	112.7	V255 T256 Y257 K261 S327	V255-S259 WeakPolarHBondContact O-CB 3.14Å; V255-S259 PolarHBondContact O-N 3.32Å; V255-S259 VanDerWaalsContact O-N 3.13Å; V255-S259 PolarHBondContact O-OG 2.64Å; T256-S259 PolarHBondContact O-N 3.08Å; Y257-S259 VanDerWaalsContact C-N 3.3Å; Y257-S259 PolarHBondContact O-N 3.5Å; S259-K261 PolarHBondContact O-N 3.1Å; S259-S327 WeakPolarHBondContact O-CB 3.23Å
260	G	88.4	Confident	94.2	Very high	61 Å²	61	41.4 Å²	41.4	63%	0.629	22%	0.224	S	C	*	.	T	Hydrogen-bonded Turn	trans	64.6	21.7	-175.5	0	0	0	0	0	113.6	T256 Y257 Y258	T256-G260 PolarHBondContact O-N 3.49Å; Y257-G260 PolarHBondContact O-N 3.04Å; Y257-G260 VanDerWaalsContact O-N 3.14Å; Y258-G260 VanDerWaalsContact C-N 3.31Å
261	K	88.3	Confident	94.2	Very high	70 Å²	70	41.4 Å²	41.4	30%	0.304	22%	0.224	S	C	.	.			trans	-92.3	148	178.5	-68.2	-174.2	177.8	174.2	0	109.4	T256 S259 E263 A322 T323 H325	T256-K261 HydrophobicContact CG2-CB 4.47Å; T256-K261 WeakPolarHBondContact CG2-O 3.31Å; T256-K261 PolarHBondContact O-N 2.91Å; S259-K261 PolarHBondContact O-N 3.1Å; K261-E263 VanDerWaalsContact C-N 3.33Å; K261-A322 PolarHBondContact NZ-O 3.2Å; K261-T323 HydrophobicContact CD-CG2 4.04Å; K261-T323 VanDerWaalsContact CD-O 3.29Å; K261-T323 WeakPolarHBondContact CD-O 3.27Å; K261-T323 WeakPolarHBondContact CE-O 3.41Å; K261-T323 PolarHBondContact NZ-O 3.14Å; K261-H325 PolarHBondContact NZ-O 3.42Å
262	K	85.8	Confident	94.2	Very high	174 Å²	174	47.7 Å²	47.7	76%	0.757	25%	0.248	S	C	*	.	S	Bend	trans	-68.9	-35.3	178	-65	-173.8	175.1	-177.5	0	112.5	M487	K262-M487 HydrophobicContact CB-SD 4.2Å; K262-M487 HydrophobicContact CD-CE 4.46Å; K262-M487 HydrophobicContact CG-CE 3.78Å; K262-M487 HydrophobicContact CG-SD 3.69Å
263	E	89.3	Confident	94.2	Very high	124 Å²	124	47.9 Å²	47.9	58%	0.579	25%	0.249	S	C	*	.	S	Bend	trans	-146.6	155	-177.3	62.8	-178	164.9	0	0	109.8	K261	K261-E263 VanDerWaalsContact C-N 3.33Å
264	P	93	Very high	94.3	Very high	11 Å²	11	47 Å²	47	7%	0.071	25%	0.245	C	C	.	.			trans	-68.4	150.3	172.1	27.1	-31.8	0	0	0	111	L180 G266 Y267 M270 T323	L180-P264 HydrophobicContact CD1-CB 4.39Å; L180-P264 HydrophobicContact CD1-CG 3.48Å; L180-P264 VanDerWaalsContact CD1-CG 3.48Å; L180-P264 HydrophobicContact CG-CG 4.32Å; P264-G266 PolarHBondContact O-N 2.96Å; P264-Y267 HydrophobicContact CG-CD2 4.43Å; P264-Y267 PolarHBondContact O-N 2.55Å; P264-M270 HydrophobicContact CB-SD 3.73Å; P264-M270 HydrophobicContact CG-SD 4Å; P264-T323 HydrophobicContact CB-CG2 4.44Å
265	F	96.3	Very high	94.5	Very high	130 Å²	130	49.5 Å²	49.5	57%	0.57	26%	0.257	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.6	122.5	177.1	179.6	-92.8	0	0	0	111.1	S319 A322 T323	F265-S319 VanDerWaalsContact O-CB 3.27Å; F265-S319 WeakPolarHBondContact O-CB 3.38Å; F265-S319 PolarHBondContact O-OG 3.21Å; F265-A322 HydrophobicContact CB-CB 3.83Å; F265-A322 HydrophobicContact CD1-CB 3.52Å; F265-A322 HydrophobicContact CD2-CB 4.22Å; F265-A322 HydrophobicContact CE1-CB 4.12Å; F265-A322 HydrophobicContact CG-CB 3.58Å; F265-T323 PolarHBondContact N-OG1 3.4Å
266	G	95.8	Very high	94.6	Very high	38 Å²	38	51.8 Å²	51.8	39%	0.392	27%	0.273	S	S	.	.	T	Hydrogen-bonded Turn	trans	67.1	44.5	179.4	0	0	0	0	0	112.7	P264 M268 G269 M270	P264-G266 PolarHBondContact O-N 2.96Å; G266-M268 VanDerWaalsContact C-N 3.27Å; G266-M268 PolarHBondContact O-N 3.29Å; G266-M268 VanDerWaalsContact O-N 3.16Å; G266-G269 CarbonylContact O-C 3.59Å; G266-G269 WeakPolarHBondContact O-CA 3.39Å; G266-G269 PolarHBondContact O-N 3.01Å; G266-M270 PolarHBondContact O-N 2.77Å
267	Y	96.1	Very high	94.8	Very high	30 Å²	30	51 Å²	51	12%	0.118	27%	0.269	C	S	.	.	H	α-helix	trans	-42	-50.6	178.2	166.2	-90.9	0	0	0	113.2	Y176 T178 L180 W183 P264 G269 M270 V271	Y176-Y267 WeakPolarHBondContact O-CE1 3.37Å; Y176-Y267 PolarHBondContact O-OH 2.91Å; T178-Y267 PolarHBondContact O-OH 3.02Å; L180-Y267 HydrophobicContact CD1-CD2 4.38Å; L180-Y267 HydrophobicContact CD2-CD2 3.63Å; L180-Y267 HydrophobicContact CD2-CE2 3.48Å; L180-Y267 VanDerWaalsContact CD2-CE2 3.48Å; L180-Y267 HydrophobicContact CG-CD2 3.8Å; L180-Y267 HydrophobicContact CG-CE2 3.81Å; W183-Y267 PolarHBondContact NE1-OH 3.32Å; W183-Y267 VanDerWaalsContact NE1-OH 3.12Å; P264-Y267 HydrophobicContact CG-CD2 4.43Å; P264-Y267 PolarHBondContact O-N 2.55Å; Y267-G269 VanDerWaalsContact C-N 3.34Å; Y267-G269 PolarHBondContact O-N 2.83Å; Y267-M270 WeakPolarHBondContact O-CB 3.31Å; Y267-M270 PolarHBondContact O-N 3.47Å; Y267-M270 VanDerWaalsContact O-N 3.1Å; Y267-V271 HydrophobicContact CE1-CG2 3.96Å; Y267-V271 HydrophobicContact CE2-CG2 4.11Å; Y267-V271 PolarHBondContact O-N 3.29Å
268	M	97.1	Very high	95	Very high	76 Å²	76	49.4 Å²	49.4	37%	0.374	26%	0.264	S	S	.	.	H	α-helix	trans	-62.2	-40.1	177.4	-70.9	-60.8	-64.8	0	0	112.6	Y176 G266 M270 V271 W272	Y176-M268 HydrophobicContact CD1-CE 3.48Å; Y176-M268 VanDerWaalsContact CD1-CE 3.48Å; Y176-M268 HydrophobicContact CD1-SD 3.9Å; Y176-M268 HydrophobicContact CE1-CE 3.72Å; Y176-M268 HydrophobicContact CG-CE 4.16Å; Y176-M268 HydrophobicContact CG-SD 4.37Å; G266-M268 VanDerWaalsContact C-N 3.27Å; G266-M268 PolarHBondContact O-N 3.29Å; G266-M268 VanDerWaalsContact O-N 3.16Å; M268-M270 VanDerWaalsContact C-N 3.27Å; M268-M270 PolarHBondContact O-N 3.32Å; M268-V271 PolarHBondContact O-N 3.13Å; M268-W272 PolarHBondContact O-N 3.45Å
269	G	97.6	Very high	95.3	Very high	32 Å²	32	54.3 Å²	54.3	33%	0.33	29%	0.286	S	S	.	.	H	α-helix	trans	-60.6	-37.5	174.3	0	0	0	0	0	112.2	G266 Y267 A273	G266-G269 CarbonylContact O-C 3.59Å; G266-G269 WeakPolarHBondContact O-CA 3.39Å; G266-G269 PolarHBondContact O-N 3.01Å; Y267-G269 VanDerWaalsContact C-N 3.34Å; Y267-G269 PolarHBondContact O-N 2.83Å; G269-A273 VanDerWaalsContact O-CB 3.22Å; G269-A273 WeakPolarHBondContact O-CB 3.42Å; G269-A273 PolarHBondContact O-N 2.96Å
270	M	98	Very high	95.6	Very high	0 Å²	0	55.1 Å²	55.1	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-69.4	-37.1	175.1	-62.6	-175.4	76.3	0	0	112.8	L180 S252 P264 G266 Y267 M268 M274 W320	L180-M270 HydrophobicContact CD1-CB 3.96Å; L180-M270 HydrophobicContact CD1-CE 3.76Å; L180-M270 HydrophobicContact CD1-CG 4.44Å; L180-M270 HydrophobicContact CD1-SD 3.6Å; L180-M270 HydrophobicContact CD2-CB 4.16Å; S252-M270 VanDerWaalsContact OG-CE 3.26Å; S252-M270 WeakPolarHBondContact OG-CE 3.29Å; P264-M270 HydrophobicContact CB-SD 3.73Å; P264-M270 HydrophobicContact CG-SD 4Å; G266-M270 PolarHBondContact O-N 2.77Å; Y267-M270 WeakPolarHBondContact O-CB 3.31Å; Y267-M270 PolarHBondContact O-N 3.47Å; Y267-M270 VanDerWaalsContact O-N 3.1Å; M268-M270 VanDerWaalsContact C-N 3.27Å; M268-M270 PolarHBondContact O-N 3.32Å; M270-M274 WeakPolarHBondContact O-CG 3.26Å; M270-M274 PolarHBondContact O-N 3.1Å; M270-W320 HydrophobicContact CE-CZ2 4.34Å
271	V	98.4	Very high	95.9	Very high	0 Å²	0	52.2 Å²	52.2	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	-62.9	-51.9	173.8	172.9	0	0	0	0	110.3	L180 W183 Y267 M268 A273 M274 M275	L180-V271 HydrophobicContact CD2-CG2 3.57Å; W183-V271 HydrophobicContact CD2-CG1 3.84Å; W183-V271 HydrophobicContact CD2-CG2 4.41Å; W183-V271 HydrophobicContact CE3-CG1 4.17Å; W183-V271 HydrophobicContact CG-CG1 4.35Å; W183-V271 HydrophobicContact CG-CG2 4.14Å; W183-V271 HydrophobicContact CH2-CG1 4.09Å; W183-V271 HydrophobicContact CZ2-CG1 3.76Å; W183-V271 HydrophobicContact CZ3-CG1 4.3Å; Y267-V271 HydrophobicContact CE1-CG2 3.96Å; Y267-V271 HydrophobicContact CE2-CG2 4.11Å; Y267-V271 PolarHBondContact O-N 3.29Å; M268-V271 PolarHBondContact O-N 3.13Å; V271-A273 VanDerWaalsContact C-N 3.32Å; V271-A273 PolarHBondContact O-N 3.07Å; V271-M274 PolarHBondContact O-N 2.78Å; V271-M275 HydrophobicContact CG1-CE 3.99Å; V271-M275 PolarHBondContact O-N 3.21Å
272	W	98.3	Very high	96.3	Very high	132 Å²	132	50.6 Å²	50.6	50%	0.5	25%	0.252	S	S	.	.	H	α-helix	trans	-60.6	-41	177.1	-72.7	113.3	0	0	0	112.1	Y176 M268 M274 M275 S276	Y176-W272 HydrophobicContact CE1-CZ2 4.44Å; M268-W272 PolarHBondContact O-N 3.45Å; W272-M274 VanDerWaalsContact C-N 3.35Å; W272-M274 PolarHBondContact O-N 3.33Å; W272-M275 HydrophobicContact CD2-CE 3.55Å; W272-M275 HydrophobicContact CE3-CE 3.1Å; W272-M275 HydrophobicContact CG-CE 4.28Å; W272-M275 HydrophobicContact CH2-CE 3.82Å; W272-M275 HydrophobicContact CZ2-CE 4.24Å; W272-M275 HydrophobicContact CZ3-CE 3.25Å; W272-M275 PolarHBondContact O-N 2.99Å; W272-S276 WeakPolarHBondContact O-CB 3.43Å; W272-S276 PolarHBondContact O-N 3.32Å; W272-S276 PolarHBondContact O-OG 3.4Å; W272-S276 VanDerWaalsContact O-OG 3.07Å
273	A	98.4	Very high	96.9	Very high	5 Å²	5	44.5 Å²	44.5	4%	0.041	23%	0.228	C	C	.	.	H	α-helix	trans	-59.5	-42.3	175.3	0	0	0	0	0	112.6	G269 V271 S276 I277 P312 V315 K316	G269-A273 VanDerWaalsContact O-CB 3.22Å; G269-A273 WeakPolarHBondContact O-CB 3.42Å; G269-A273 PolarHBondContact O-N 2.96Å; V271-A273 VanDerWaalsContact C-N 3.32Å; V271-A273 PolarHBondContact O-N 3.07Å; A273-S276 PolarHBondContact O-N 3.43Å; A273-I277 VanDerWaalsContact O-CG1 3.28Å; A273-I277 WeakPolarHBondContact O-CG1 3.32Å; A273-I277 PolarHBondContact O-N 2.97Å; A273-P312 HydrophobicContact CB-CB 3.89Å; A273-P312 WeakPolarHBondContact CB-O 3.15Å; A273-V315 HydrophobicContact CB-CB 4.39Å; A273-V315 HydrophobicContact CB-CG1 4.3Å; A273-K316 HydrophobicContact CB-CD 4.2Å; A273-K316 HydrophobicContact CB-CG 3.82Å
274	M	98.4	Very high	97.3	Very high	0 Å²	0	38.6 Å²	38.6	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-65.6	-42.2	176	-70.6	-174.8	-66.1	0	0	112.4	L180 W183 I187 L245 M270 V271 W272 S276 I277 G278 K316	L180-M274 HydrophobicContact CB-CE 4.44Å; L180-M274 HydrophobicContact CD2-CE 3.75Å; W183-M274 HydrophobicContact CB-CE 3.71Å; I187-M274 HydrophobicContact CD1-CB 3.39Å; L245-M274 HydrophobicContact CD2-CB 4.25Å; L245-M274 HydrophobicContact CD2-CG 4.2Å; M270-M274 WeakPolarHBondContact O-CG 3.26Å; M270-M274 PolarHBondContact O-N 3.1Å; V271-M274 PolarHBondContact O-N 2.78Å; W272-M274 VanDerWaalsContact C-N 3.35Å; W272-M274 PolarHBondContact O-N 3.33Å; M274-S276 VanDerWaalsContact C-N 3.34Å; M274-I277 PolarHBondContact O-N 2.72Å; M274-G278 PolarHBondContact O-N 3.46Å; M274-K316 HydrophobicContact CG-CD 4.18Å; M274-K316 PolarHBondContact SD-NZ 3.16Å
275	M	98.4	Very high	97.6	Very high	51 Å²	51	40.8 Å²	40.8	25%	0.251	21%	0.207	S	C	.	.	H	α-helix	trans	-64.8	-40.4	177.3	-68.7	-171.2	-60.2	0	0	111.3	W183 I187 V271 W272 G278 F279	W183-M275 HydrophobicContact CH2-SD 4.39Å; W183-M275 HydrophobicContact CZ3-SD 4Å; I187-M275 HydrophobicContact CD1-CG 3.8Å; I187-M275 HydrophobicContact CG1-CG 4.33Å; V271-M275 HydrophobicContact CG1-CE 3.99Å; V271-M275 PolarHBondContact O-N 3.21Å; W272-M275 HydrophobicContact CD2-CE 3.55Å; W272-M275 HydrophobicContact CE3-CE 3.1Å; W272-M275 HydrophobicContact CG-CE 4.28Å; W272-M275 HydrophobicContact CH2-CE 3.82Å; W272-M275 HydrophobicContact CZ2-CE 4.24Å; W272-M275 HydrophobicContact CZ3-CE 3.25Å; W272-M275 PolarHBondContact O-N 2.99Å; M275-G278 PolarHBondContact O-N 3.44Å; M275-F279 PolarHBondContact O-N 3.16Å
276	S	98.4	Very high	97.6	Very high	52 Å²	52	34.6 Å²	34.6	36%	0.364	18%	0.18	S	C	.	.	H	α-helix	trans	-61.2	-44.7	173.7	-63.7	0	0	0	0	111.9	W272 A273 M274 G278 F279 L280	W272-S276 WeakPolarHBondContact O-CB 3.43Å; W272-S276 PolarHBondContact O-N 3.32Å; W272-S276 PolarHBondContact O-OG 3.4Å; W272-S276 VanDerWaalsContact O-OG 3.07Å; A273-S276 PolarHBondContact O-N 3.43Å; M274-S276 VanDerWaalsContact C-N 3.34Å; S276-G278 PolarHBondContact O-N 3.21Å; S276-F279 PolarHBondContact O-N 2.83Å; S276-L280 VanDerWaalsContact O-CB 3.26Å; S276-L280 WeakPolarHBondContact O-CB 3.3Å; S276-L280 WeakPolarHBondContact O-CG 3.41Å; S276-L280 PolarHBondContact O-N 3.41Å
277	I	98.1	Very high	97.7	Very high	0 Å²	0	33.9 Å²	33.9	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-60.4	-46.2	175.5	-69.8	163.5	0	0	0	110.5	Y241 L245 F248 A273 M274 F279 L280 G281 I309 P312 K316	Y241-I277 HydrophobicContact CD1-CG2 3.46Å; Y241-I277 VanDerWaalsContact CD1-CG2 3.46Å; Y241-I277 HydrophobicContact CD2-CG2 4.24Å; Y241-I277 HydrophobicContact CE1-CG2 3.74Å; Y241-I277 HydrophobicContact CE2-CG2 4.42Å; Y241-I277 HydrophobicContact CG-CG2 3.8Å; L245-I277 HydrophobicContact CD2-CG2 4.26Å; F248-I277 HydrophobicContact CE2-CD1 4.16Å; A273-I277 VanDerWaalsContact O-CG1 3.28Å; A273-I277 WeakPolarHBondContact O-CG1 3.32Å; A273-I277 PolarHBondContact O-N 2.97Å; M274-I277 PolarHBondContact O-N 2.72Å; I277-F279 PolarHBondContact O-N 2.96Å; I277-L280 PolarHBondContact O-N 3.26Å; I277-G281 PolarHBondContact O-N 3.48Å; I277-I309 HydrophobicContact CG1-CG2 4.4Å; I277-P312 HydrophobicContact CD1-CB 4.34Å; I277-P312 HydrophobicContact CG1-CB 3.97Å; I277-P312 HydrophobicContact CG1-CG 3.82Å; I277-K316 HydrophobicContact CD1-CD 4.08Å
278	G	97.8	Very high	97.8	Very high	4 Å²	4	34.5 Å²	34.5	4%	0.041	17%	0.17	C	C	.	.	H	α-helix	trans	-59.9	-45.3	178.2	0	0	0	0	0	112.9	L191 M274 M275 S276	L191-G278 WeakPolarHBondContact CD2-O 3.34Å; M274-G278 PolarHBondContact O-N 3.46Å; M275-G278 PolarHBondContact O-N 3.44Å; S276-G278 PolarHBondContact O-N 3.21Å
279	F	98.1	Very high	97.9	Very high	141 Å²	141	30.9 Å²	30.9	62%	0.618	15%	0.152	S	C	*	.	H	α-helix	trans	-66.4	-49.8	176.9	176.3	-99.2	0	0	0	112.3	M275 S276 I277 G281 F282 I283	M275-F279 PolarHBondContact O-N 3.16Å; S276-F279 PolarHBondContact O-N 2.83Å; I277-F279 PolarHBondContact O-N 2.96Å; F279-G281 PolarHBondContact O-N 2.97Å; F279-F282 PolarHBondContact O-N 3.14Å; F279-I283 HydrophobicContact CE1-CD1 4.4Å
280	L	96.8	Very high	97.9	Very high	26 Å²	26	29.5 Å²	29.5	14%	0.136	14%	0.137	C	C	.	.	H	α-helix	trans	-62.5	-27.9	-178.2	-68.8	173.1	0	0	0	111.8	S276 I277 F282 I283 I308 I309 P312	S276-L280 VanDerWaalsContact O-CB 3.26Å; S276-L280 WeakPolarHBondContact O-CB 3.3Å; S276-L280 WeakPolarHBondContact O-CG 3.41Å; S276-L280 PolarHBondContact O-N 3.41Å; I277-L280 PolarHBondContact O-N 3.26Å; L280-F282 PolarHBondContact O-N 2.93Å; L280-F282 VanDerWaalsContact O-N 3.16Å; L280-I283 HydrophobicContact CD2-CD1 3.68Å; L280-I283 HydrophobicContact CD2-CG1 4.22Å; L280-I283 VanDerWaalsContact O-CG1 3.29Å; L280-I283 WeakPolarHBondContact O-CG1 3.46Å; L280-I283 PolarHBondContact O-N 3.49Å; L280-I308 HydrophobicContact CD1-CG2 4.01Å; L280-I309 HydrophobicContact CB-CD1 3.94Å; L280-I309 HydrophobicContact CB-CG1 3.77Å; L280-I309 HydrophobicContact CD1-CG1 3.9Å; L280-I309 HydrophobicContact CG-CG1 4.44Å; L280-P312 HydrophobicContact CD1-CG 4.4Å
281	G	95.4	Very high	97.8	Very high	0 Å²	0	32.6 Å²	32.6	0%	0	16%	0.156	C	C	.	.	G	3₁₀ helix	trans	-57.6	-26.9	176.9	0	0	0	0	0	115	P238 I277 F279	P238-G281 WeakPolarHBondContact CD-O 3.37Å; I277-G281 PolarHBondContact O-N 3.48Å; F279-G281 PolarHBondContact O-N 2.97Å
282	F	97.7	Very high	97.7	Very high	36 Å²	36	34.5 Å²	34.5	16%	0.158	17%	0.168	C	C	.	.	G	3₁₀ helix	trans	-84.5	-6.4	176.4	-76.5	-70.2	0	0	0	114.7	L191 L194 F234 P238 F279 L280 W285	L191-F282 HydrophobicContact CD2-CD2 4.07Å; L191-F282 HydrophobicContact CD2-CE2 3.34Å; L191-F282 HydrophobicContact CD2-CZ 4.02Å; L194-F282 HydrophobicContact CB-CE1 4.24Å; L194-F282 HydrophobicContact CB-CE2 4.28Å; L194-F282 HydrophobicContact CB-CZ 3.61Å; L194-F282 HydrophobicContact CD1-CE2 4.19Å; L194-F282 HydrophobicContact CD1-CZ 4.36Å; F234-F282 AromaticContact CE1-CD1 3.97Å; F234-F282 HydrophobicContact CE1-CD1 3.97Å; F234-F282 HydrophobicContact CE1-CE1 4.13Å; F234-F282 HydrophobicContact CE2-CD1 4.34Å; F234-F282 AromaticContact CZ-CD1 3.75Å; F234-F282 HydrophobicContact CZ-CD1 3.75Å; F234-F282 HydrophobicContact CZ-CE1 4.33Å; P238-F282 HydrophobicContact CB-CE1 4.08Å; P238-F282 HydrophobicContact CB-CZ 4.22Å; P238-F282 HydrophobicContact CG-CD1 3.65Å; P238-F282 HydrophobicContact CG-CE1 3.61Å; P238-F282 HydrophobicContact CG-CG 4.24Å; P238-F282 HydrophobicContact CG-CZ 4.18Å; F279-F282 PolarHBondContact O-N 3.14Å; L280-F282 PolarHBondContact O-N 2.93Å; L280-F282 VanDerWaalsContact O-N 3.16Å; F282-W285 WeakPolarHBondContact O-CZ3 2.84Å
283	I	97.5	Very high	97.6	Very high	46 Å²	46	31.5 Å²	31.5	24%	0.236	18%	0.178	C	C	.	.	G	3₁₀ helix	trans	-119	12.2	-175.6	68.5	168.7	0	0	0	113.6	F279 L280 F302	F279-I283 HydrophobicContact CE1-CD1 4.4Å; L280-I283 HydrophobicContact CD2-CD1 3.68Å; L280-I283 HydrophobicContact CD2-CG1 4.22Å; L280-I283 VanDerWaalsContact O-CG1 3.29Å; L280-I283 WeakPolarHBondContact O-CG1 3.46Å; L280-I283 PolarHBondContact O-N 3.49Å; I283-F302 WeakPolarHBondContact O-CE1 3.5Å
284	V	98.2	Very high	97.4	Very high	0 Å²	0	32.4 Å²	32.4	0%	0	18%	0.182	C	C	.	.			trans	-124.6	1.7	-177.1	-60.2	0	0	0	0	114.4	H237 A286 H287 A305 I309	H237-V284 WeakPolarHBondContact CD2-CG2 3.45Å; H237-V284 WeakPolarHBondContact NE2-CG2 3.23Å; V284-A286 PolarHBondContact O-N 3.48Å; V284-H287 PolarHBondContact O-CE1 3.21Å; V284-H287 VanDerWaalsContact O-CG 3.31Å; V284-H287 PolarHBondContact O-N 3Å; V284-H287 PolarHBondContact O-ND1 3.28Å; V284-A305 HydrophobicContact CG1-CB 3.87Å; V284-I309 HydrophobicContact CB-CD1 4.22Å; V284-I309 HydrophobicContact CG1-CD1 3.75Å; V284-I309 HydrophobicContact CG1-CG1 4.47Å; V284-I309 HydrophobicContact CG2-CD1 3.65Å
285	W	98.3	Very high	97.3	Very high	57 Å²	57	36.6 Å²	36.6	22%	0.216	20%	0.204	C	C	.	.	G	3₁₀ helix	trans	-55.8	-32.5	-168.3	73.7	92.5	0	0	0	115	H230 W233 F234 H237 F282 H287 H288 F302	H230-W285 AromaticContact ND1-NE1 3.49Å; H230-W285 PolarHBondContact ND1-NE1 3.45Å; W233-W285 HydrophobicContact CB-CB 4.23Å; W233-W285 VanDerWaalsContact O-CB 3.26Å; W233-W285 WeakPolarHBondContact O-CB 3.37Å; F234-W285 HydrophobicContact CB-CG 4.36Å; F234-W285 HydrophobicContact CD2-CD2 4.04Å; F234-W285 AromaticContact CD2-CE3 3.98Å; F234-W285 HydrophobicContact CD2-CE3 3.98Å; F234-W285 HydrophobicContact CD2-CZ3 4.26Å; F234-W285 HydrophobicContact CE2-CE3 4.43Å; F234-W285 HydrophobicContact CE2-CZ3 4.42Å; H237-W285 HydrophobicContact CB-CB 4.16Å; F282-W285 WeakPolarHBondContact O-CZ3 2.84Å; W285-H287 PolarHBondContact O-N 3.48Å; W285-H288 PolarHBondContact O-CD2 2.86Å; W285-H288 VanDerWaalsContact O-CD2 3.32Å; W285-H288 PolarHBondContact O-N 3.04Å; W285-F302 HydrophobicContact CD2-CE1 4.23Å; W285-F302 HydrophobicContact CD2-CZ 4.32Å; W285-F302 HydrophobicContact CE3-CE1 4.1Å; W285-F302 HydrophobicContact CE3-CZ 4.31Å; W285-F302 AromaticContact CH2-CZ 3.96Å; W285-F302 HydrophobicContact CH2-CZ 3.96Å; W285-F302 AromaticContact CZ2-CZ 3.95Å; W285-F302 HydrophobicContact CZ2-CZ 3.95Å; W285-F302 HydrophobicContact CZ3-CE1 4.25Å; W285-F302 HydrophobicContact CZ3-CZ 4.14Å
286	A	97.6	Very high	97.2	Very high	0 Å²	0	38.8 Å²	38.8	0%	0	22%	0.22	C	C	.	.	G	3₁₀ helix	trans	-75.8	-1.5	-173.2	0	0	0	0	0	114	V284 H288 M289 M294 F302	V284-A286 PolarHBondContact O-N 3.48Å; A286-H288 PolarHBondContact O-N 3.46Å; A286-M289 WeakPolarHBondContact O-CA 3.46Å; A286-M289 WeakPolarHBondContact O-CB 3.43Å; A286-M289 PolarHBondContact O-N 3.23Å; A286-M294 HydrophobicContact CB-CE 4.03Å; A286-M294 HydrophobicContact CB-SD 3.99Å; A286-M294 WeakPolarHBondContact O-CE 3.16Å; A286-F302 HydrophobicContact CB-CD1 3.83Å; A286-F302 HydrophobicContact CB-CD2 3.66Å; A286-F302 HydrophobicContact CB-CE1 3.63Å; A286-F302 HydrophobicContact CB-CE2 3.46Å; A286-F302 VanDerWaalsContact CB-CE2 3.46Å; A286-F302 HydrophobicContact CB-CG 3.85Å; A286-F302 HydrophobicContact CB-CZ 3.45Å; A286-F302 VanDerWaalsContact CB-CZ 3.45Å
287	H	98.2	Very high	97.1	Very high	23 Å²	23	42.4 Å²	42.4	11%	0.106	24%	0.236	C	C	.	.	G	3₁₀ helix	trans	-63.1	-20.6	169.3	61.1	-130.8	0	0	0	113.1	H237 V284 W285 M289 F290 T306	H237-H287 AromaticContact CE1-CE1 3.02Å; H237-H287 PolarHBondContact CE1-CE1 3.22Å; H237-H287 AromaticContact CE1-NE2 3.23Å; H237-H287 PolarHBondContact CE1-NE2 3.32Å; H237-H287 AromaticContact CG-CE1 3.83Å; H237-H287 AromaticContact CG-NE2 3.88Å; H237-H287 AromaticContact ND1-CE1 3.06Å; H237-H287 PolarHBondContact ND1-CE1 3.4Å; H237-H287 AromaticContact ND1-NE2 2.89Å; H237-H287 PolarHBondContact ND1-NE2 3.33Å; H237-H287 AromaticContact NE2-CE1 3.66Å; V284-H287 PolarHBondContact O-CE1 3.21Å; V284-H287 VanDerWaalsContact O-CG 3.31Å; V284-H287 PolarHBondContact O-N 3Å; V284-H287 PolarHBondContact O-ND1 3.28Å; W285-H287 PolarHBondContact O-N 3.48Å; H287-M289 PolarHBondContact O-N 2.85Å; H287-F290 HydrophobicContact CB-CD2 4.18Å; H287-F290 HydrophobicContact CB-CE1 4.2Å; H287-F290 HydrophobicContact CB-CE2 3.46Å; H287-F290 VanDerWaalsContact CB-CE2 3.46Å; H287-F290 HydrophobicContact CB-CZ 3.48Å; H287-F290 VanDerWaalsContact CB-CZ 3.48Å; H287-F290 VanDerWaalsContact O-CD2 3.22Å; H287-F290 WeakPolarHBondContact O-CD2 3.43Å; H287-T306 VanDerWaalsContact ND1-CG2 3.31Å; H287-T306 WeakPolarHBondContact ND1-CG2 3.17Å; H287-T306 PolarHBondContact ND1-OG1 3.47Å
288	H	98.1	Very high	97.1	Very high	44 Å²	44	44.5 Å²	44.5	20%	0.204	25%	0.249	C	C	.	.	G	3₁₀ helix	trans	-75.7	0.5	172.7	-62.9	-70.6	0	0	0	113	W233 H237 W285 A286 H365	W233-H288 HydrophobicContact CD2-CB 3.4Å; W233-H288 VanDerWaalsContact CD2-CB 3.4Å; W233-H288 AromaticContact CD2-CD2 3.54Å; W233-H288 AromaticContact CD2-CG 3.55Å; W233-H288 AromaticContact CE2-CG 3.74Å; W233-H288 HydrophobicContact CE3-CB 3.97Å; W233-H288 AromaticContact CE3-CD2 3.24Å; W233-H288 AromaticContact CE3-CG 3.55Å; W233-H288 AromaticContact CE3-NE2 3.63Å; W233-H288 HydrophobicContact CG-CB 3.67Å; W233-H288 HydrophobicContact CH2-CB 4.31Å; W233-H288 AromaticContact CH2-CG 4Å; W233-H288 AromaticContact CH2-ND1 3.9Å; W233-H288 HydrophobicContact CZ2-CB 3.78Å; W233-H288 AromaticContact CZ2-CG 3.99Å; W233-H288 HydrophobicContact CZ3-CB 4.38Å; W233-H288 AromaticContact CZ3-CD2 3.72Å; W233-H288 AromaticContact CZ3-CE1 3.81Å; W233-H288 AromaticContact CZ3-CG 3.78Å; W233-H288 AromaticContact CZ3-ND1 3.85Å; W233-H288 AromaticContact CZ3-NE2 3.72Å; H237-H288 AromaticContact ND1-NE2 3.31Å; H237-H288 PolarHBondContact ND1-NE2 3.4Å; W285-H288 PolarHBondContact O-CD2 2.86Å; W285-H288 VanDerWaalsContact O-CD2 3.32Å; W285-H288 PolarHBondContact O-N 3.04Å; A286-H288 PolarHBondContact O-N 3.46Å; H288-H365 PolarHBondContact O-CE1 2.99Å
289	M	97.8	Very high	97	Very high	0 Å²	0	47 Å²	47	0%	0	26%	0.257	C	S	.	.	G	3₁₀ helix	trans	-126.7	14.9	-171.5	-56.1	173.9	60.7	0	0	111.6	I226 Q229 H230 A286 H287 T291 V292 M294	I226-M289 HydrophobicContact CG2-CE 3.77Å; Q229-M289 HydrophobicContact CB-CE 3.58Å; Q229-M289 HydrophobicContact CB-CG 4.4Å; Q229-M289 HydrophobicContact CB-SD 4.02Å; H230-M289 VanDerWaalsContact CD2-CE 3.44Å; H230-M289 WeakPolarHBondContact CD2-CE 3.19Å; H230-M289 WeakPolarHBondContact NE2-CE 3.49Å; A286-M289 WeakPolarHBondContact O-CA 3.46Å; A286-M289 WeakPolarHBondContact O-CB 3.43Å; A286-M289 PolarHBondContact O-N 3.23Å; H287-M289 PolarHBondContact O-N 2.85Å; M289-T291 PolarHBondContact O-N 3.37Å; M289-V292 HydrophobicContact CB-CG1 3.98Å; M289-V292 HydrophobicContact CB-CG2 4.03Å; M289-V292 HydrophobicContact CE-CG2 4.17Å; M289-V292 VanDerWaalsContact O-CG2 3.24Å; M289-V292 WeakPolarHBondContact O-CG2 3.28Å; M289-V292 PolarHBondContact O-N 2.9Å; M289-M294 HydrophobicContact CB-CE 4.19Å
290	F	97.7	Very high	97	Very high	2 Å²	2	42.6 Å²	42.6	1%	0.009	25%	0.246	C	C	.	.	T	Hydrogen-bonded Turn	trans	-58.7	-21	-174.8	-73.1	-38.1	0	0	0	114.6	H287 M294 R299 F302 D361	H287-F290 HydrophobicContact CB-CD2 4.18Å; H287-F290 HydrophobicContact CB-CE1 4.2Å; H287-F290 HydrophobicContact CB-CE2 3.46Å; H287-F290 VanDerWaalsContact CB-CE2 3.46Å; H287-F290 HydrophobicContact CB-CZ 3.48Å; H287-F290 VanDerWaalsContact CB-CZ 3.48Å; H287-F290 VanDerWaalsContact O-CD2 3.22Å; H287-F290 WeakPolarHBondContact O-CD2 3.43Å; F290-M294 HydrophobicContact CD1-CE 3.89Å; F290-R299 HydrophobicContact CD1-CB 4.43Å; F290-R299 HydrophobicContact CD1-CG 4.05Å; F290-F302 HydrophobicContact CE1-CB 3.69Å; F290-F302 HydrophobicContact CZ-CB 4.08Å; F290-D361 HydrophobicContact CB-CB 4.38Å; F290-D361 HydrophobicContact CD2-CB 3.83Å
291	T	96.6	Very high	97	Very high	66 Å²	66	46.9 Å²	46.9	41%	0.405	26%	0.261	S	S	.	.	T	Hydrogen-bonded Turn	trans	-91.8	-5.6	179.5	53.7	0	0	0	0	114.5	M289 G293 H365	M289-T291 PolarHBondContact O-N 3.37Å; T291-G293 PolarHBondContact O-N 2.87Å; T291-H365 HydrophobicContact CG2-CB 3.48Å; T291-H365 VanDerWaalsContact CG2-CB 3.48Å; T291-H365 VanDerWaalsContact CG2-CG 3.48Å; T291-H365 PolarHBondContact OG1-CD2 2.78Å; T291-H365 VanDerWaalsContact OG1-CD2 3.32Å; T291-H365 PolarHBondContact OG1-NE2 2.79Å
292	V	96.2	Very high	97.2	Very high	39 Å²	39	47.6 Å²	47.6	24%	0.236	26%	0.264	C	S	.	.	S	Bend	trans	-79.4	1	-176.9	-48.5	0	0	0	0	114.1	I226 M289 M294	I226-V292 HydrophobicContact CD1-CB 4.44Å; I226-V292 HydrophobicContact CG2-CG2 4.22Å; M289-V292 HydrophobicContact CB-CG1 3.98Å; M289-V292 HydrophobicContact CB-CG2 4.03Å; M289-V292 HydrophobicContact CE-CG2 4.17Å; M289-V292 VanDerWaalsContact O-CG2 3.24Å; M289-V292 WeakPolarHBondContact O-CG2 3.28Å; M289-V292 PolarHBondContact O-N 2.9Å; V292-M294 HydrophobicContact CG2-CG 3.89Å
293	G	95.3	Very high	97.2	Very high	70 Å²	70	46.6 Å²	46.6	72%	0.722	26%	0.262	S	S	*	.			trans	89.2	25.9	179.1	0	0	0	0	0	115.1	T291	T291-G293 PolarHBondContact O-N 2.87Å
294	M	95.4	Very high	97.2	Very high	24 Å²	24	47.7 Å²	47.7	12%	0.118	27%	0.273	C	S	.	.			trans	-58.9	149.3	170.5	-65.3	-171	-65.7	0	0	111.6	A286 M289 F290 V292 T298 R299	A286-M294 HydrophobicContact CB-CE 4.03Å; A286-M294 HydrophobicContact CB-SD 3.99Å; A286-M294 WeakPolarHBondContact O-CE 3.16Å; M289-M294 HydrophobicContact CB-CE 4.19Å; F290-M294 HydrophobicContact CD1-CE 3.89Å; V292-M294 HydrophobicContact CG2-CG 3.89Å; M294-T298 HydrophobicContact CB-CG2 4.22Å; M294-T298 HydrophobicContact CG-CG2 4.44Å; M294-T298 HydrophobicContact SD-CG2 3.7Å; M294-R299 HydrophobicContact CB-CG 4.01Å; M294-R299 HydrophobicContact CE-CG 4.26Å; M294-R299 PolarHBondContact O-NE 3.43Å
295	D	95.9	Very high	97.2	Very high	87 Å²	87	48.1 Å²	48.1	47%	0.465	28%	0.276	S	S	.	.			trans	-61.1	163.4	177.3	70.1	-90.3	0	0	0	112.3	D297 T298 R299	D295-D297 VanDerWaalsContact C-N 3.33Å; D295-D297 PolarHBondContact O-N 2.88Å; D295-D297 WeakPolarHBondContact OD2-CB 3.44Å; D295-D297 PolarHBondContact OD2-N 3.37Å; D295-T298 VanDerWaalsContact CG-OG1 3.27Å; D295-T298 VanDerWaalsContact OD1-CB 3.29Å; D295-T298 WeakPolarHBondContact OD1-CB 3.36Å; D295-T298 PolarHBondContact OD1-OG1 3.02Å; D295-T298 PolarHBondContact OD2-N 3.48Å; D295-T298 PolarHBondContact OD2-OG1 3.4Å; D295-R299 WeakPolarHBondContact O-CG 3.02Å; D295-R299 PolarHBondContact O-N 2.94Å; D295-R299 VanDerWaalsContact O-N 3.1Å
296	V	95.6	Very high	97.1	Very high	98 Å²	98	46.3 Å²	46.3	59%	0.594	27%	0.272	S	S	*	.	H	α-helix	trans	-63.8	-39.1	-174.1	178	0	0	0	0	111.7	R299 A300	V296-R299 PolarHBondContact O-N 3.47Å; V296-A300 WeakPolarHBondContact O-CB 3.36Å; V296-A300 PolarHBondContact O-N 3.08Å
297	D	97.5	Very high	97.1	Very high	128 Å²	128	49.3 Å²	49.3	68%	0.684	29%	0.287	S	S	*	.	H	α-helix	trans	-71.8	-41.6	-175.9	-65.6	-23.2	0	0	0	110.8	D295 R299 A300 Y301	D295-D297 VanDerWaalsContact C-N 3.33Å; D295-D297 PolarHBondContact O-N 2.88Å; D295-D297 WeakPolarHBondContact OD2-CB 3.44Å; D295-D297 PolarHBondContact OD2-N 3.37Å; D297-R299 PolarHBondContact O-N 3Å; D297-A300 PolarHBondContact O-N 3.05Å; D297-Y301 WeakPolarHBondContact O-CB 3.36Å; D297-Y301 PolarHBondContact O-N 3.38Å
298	T	96.8	Very high	97.1	Very high	44 Å²	44	52.3 Å²	52.3	27%	0.27	30%	0.302	S	S	.	.	H	α-helix	trans	-59	-46.2	172.7	-65.1	0	0	0	0	110.8	M294 D295 A300 Y301 F302	M294-T298 HydrophobicContact CB-CG2 4.22Å; M294-T298 HydrophobicContact CG-CG2 4.44Å; M294-T298 HydrophobicContact SD-CG2 3.7Å; D295-T298 VanDerWaalsContact CG-OG1 3.27Å; D295-T298 VanDerWaalsContact OD1-CB 3.29Å; D295-T298 WeakPolarHBondContact OD1-CB 3.36Å; D295-T298 PolarHBondContact OD1-OG1 3.02Å; D295-T298 PolarHBondContact OD2-N 3.48Å; D295-T298 PolarHBondContact OD2-OG1 3.4Å; T298-A300 PolarHBondContact O-N 3.02Å; T298-Y301 PolarHBondContact O-N 3.38Å; T298-F302 HydrophobicContact CG2-CD2 3.76Å; T298-F302 HydrophobicContact CG2-CE2 3.87Å; T298-F302 VanDerWaalsContact O-CD2 3.31Å; T298-F302 WeakPolarHBondContact O-CD2 3.4Å; T298-F302 PolarHBondContact O-N 3.16Å
299	R	96.8	Very high	97.1	Very high	56 Å²	56	50.5 Å²	50.5	21%	0.211	29%	0.294	C	S	.	.	H	α-helix	trans	-64.3	-38.8	176.4	-71.4	-171	-67.9	156.4	2.1	112.7	F290 M294 D295 V296 D297 T303	F290-R299 HydrophobicContact CD1-CB 4.43Å; F290-R299 HydrophobicContact CD1-CG 4.05Å; M294-R299 HydrophobicContact CB-CG 4.01Å; M294-R299 HydrophobicContact CE-CG 4.26Å; M294-R299 PolarHBondContact O-NE 3.43Å; D295-R299 WeakPolarHBondContact O-CG 3.02Å; D295-R299 PolarHBondContact O-N 2.94Å; D295-R299 VanDerWaalsContact O-N 3.1Å; V296-R299 PolarHBondContact O-N 3.47Å; D297-R299 PolarHBondContact O-N 3Å; R299-T303 VanDerWaalsContact O-CB 3.27Å; R299-T303 WeakPolarHBondContact O-CB 3.41Å; R299-T303 PolarHBondContact O-N 2.94Å; R299-T303 PolarHBondContact O-OG1 2.87Å
300	A	97.1	Very high	97	Very high	48 Å²	48	52.4 Å²	52.4	40%	0.397	31%	0.31	S	S	.	.	H	α-helix	trans	-65.3	-41.3	176.2	0	0	0	0	0	112.1	V296 D297 T298 S304	V296-A300 WeakPolarHBondContact O-CB 3.36Å; V296-A300 PolarHBondContact O-N 3.08Å; D297-A300 PolarHBondContact O-N 3.05Å; T298-A300 PolarHBondContact O-N 3.02Å; A300-S304 WeakPolarHBondContact O-CB 3.46Å; A300-S304 PolarHBondContact O-N 3.45Å; A300-S304 PolarHBondContact O-OG 3.24Å
301	Y	98.2	Very high	97.1	Very high	116 Å²	116	57.8 Å²	57.8	46%	0.455	34%	0.337	S	S	.	.	H	α-helix	trans	-59.1	-56.3	173.4	169.6	-96.7	0	0	0	111.1	D297 T298 T303 S304 A305	D297-Y301 WeakPolarHBondContact O-CB 3.36Å; D297-Y301 PolarHBondContact O-N 3.38Å; T298-Y301 PolarHBondContact O-N 3.38Å; Y301-T303 VanDerWaalsContact C-N 3.28Å; Y301-T303 PolarHBondContact O-N 3.3Å; Y301-S304 PolarHBondContact O-N 3.3Å; Y301-S304 VanDerWaalsContact O-N 3.12Å; Y301-A305 HydrophobicContact CE1-CB 4.41Å; Y301-A305 WeakPolarHBondContact O-CB 3.48Å; Y301-A305 PolarHBondContact O-N 3.21Å
302	F	98.1	Very high	97.1	Very high	15 Å²	15	55.1 Å²	55.1	7%	0.066	32%	0.322	C	S	.	.	H	α-helix	trans	-66.1	-31.3	-176.6	-83.8	-73.1	0	0	0	112.5	I283 W285 A286 F290 T298 T306	I283-F302 WeakPolarHBondContact O-CE1 3.5Å; W285-F302 HydrophobicContact CD2-CE1 4.23Å; W285-F302 HydrophobicContact CD2-CZ 4.32Å; W285-F302 HydrophobicContact CE3-CE1 4.1Å; W285-F302 HydrophobicContact CE3-CZ 4.31Å; W285-F302 AromaticContact CH2-CZ 3.96Å; W285-F302 HydrophobicContact CH2-CZ 3.96Å; W285-F302 AromaticContact CZ2-CZ 3.95Å; W285-F302 HydrophobicContact CZ2-CZ 3.95Å; W285-F302 HydrophobicContact CZ3-CE1 4.25Å; W285-F302 HydrophobicContact CZ3-CZ 4.14Å; A286-F302 HydrophobicContact CB-CD1 3.83Å; A286-F302 HydrophobicContact CB-CD2 3.66Å; A286-F302 HydrophobicContact CB-CE1 3.63Å; A286-F302 HydrophobicContact CB-CE2 3.46Å; A286-F302 VanDerWaalsContact CB-CE2 3.46Å; A286-F302 HydrophobicContact CB-CG 3.85Å; A286-F302 HydrophobicContact CB-CZ 3.45Å; A286-F302 VanDerWaalsContact CB-CZ 3.45Å; F290-F302 HydrophobicContact CE1-CB 3.69Å; F290-F302 HydrophobicContact CZ-CB 4.08Å; T298-F302 HydrophobicContact CG2-CD2 3.76Å; T298-F302 HydrophobicContact CG2-CE2 3.87Å; T298-F302 VanDerWaalsContact O-CD2 3.31Å; T298-F302 WeakPolarHBondContact O-CD2 3.4Å; T298-F302 PolarHBondContact O-N 3.16Å; F302-T306 WeakPolarHBondContact O-CB 3.14Å; F302-T306 PolarHBondContact O-N 3.49Å; F302-T306 PolarHBondContact O-OG1 3.06Å
303	T	98	Very high	97.2	Very high	16 Å²	16	54.6 Å²	54.6	10%	0.098	32%	0.318	C	S	.	.	H	α-helix	trans	-60	-53.6	170.1	-64	0	0	0	0	110.6	R299 Y301 T306 M307 A356 S358	R299-T303 VanDerWaalsContact O-CB 3.27Å; R299-T303 WeakPolarHBondContact O-CB 3.41Å; R299-T303 PolarHBondContact O-N 2.94Å; R299-T303 PolarHBondContact O-OG1 2.87Å; Y301-T303 VanDerWaalsContact C-N 3.28Å; Y301-T303 PolarHBondContact O-N 3.3Å; T303-T306 PolarHBondContact O-N 2.91Å; T303-M307 HydrophobicContact CG2-CE 3.79Å; T303-M307 HydrophobicContact CG2-SD 4.18Å; T303-M307 WeakPolarHBondContact O-CG 3.4Å; T303-M307 PolarHBondContact O-N 3.02Å; T303-A356 WeakPolarHBondContact CA-O 3.5Å; T303-A356 WeakPolarHBondContact CG2-O 3.44Å; T303-S358 VanDerWaalsContact OG1-CB 3.3Å; T303-S358 WeakPolarHBondContact OG1-CB 3.2Å; T303-S358 PolarHBondContact OG1-N 2.72Å; T303-S358 PolarHBondContact OG1-OG 2.99Å
304	S	97.6	Very high	97.3	Very high	69 Å²	69	52.2 Å²	52.2	48%	0.483	29%	0.293	S	S	.	.	H	α-helix	trans	-63.9	-47.2	-177.3	-55.4	0	0	0	0	111.8	A300 Y301 T306 M307 I308	A300-S304 WeakPolarHBondContact O-CB 3.46Å; A300-S304 PolarHBondContact O-N 3.45Å; A300-S304 PolarHBondContact O-OG 3.24Å; Y301-S304 PolarHBondContact O-N 3.3Å; Y301-S304 VanDerWaalsContact O-N 3.12Å; S304-T306 PolarHBondContact O-N 3.42Å; S304-M307 PolarHBondContact O-N 3.47Å; S304-I308 WeakPolarHBondContact O-CG1 3.49Å; S304-I308 PolarHBondContact O-N 2.95Å; S304-I308 VanDerWaalsContact O-N 3.11Å
305	A	97.8	Very high	97.4	Very high	8 Å²	8	53.9 Å²	53.9	7%	0.066	31%	0.305	C	S	.	.	H	α-helix	trans	-61.9	-41.6	179.7	0	0	0	0	0	112	V284 Y301 I308	V284-A305 HydrophobicContact CG1-CB 3.87Å; Y301-A305 HydrophobicContact CE1-CB 4.41Å; Y301-A305 WeakPolarHBondContact O-CB 3.48Å; Y301-A305 PolarHBondContact O-N 3.21Å; A305-I308 PolarHBondContact O-N 2.98Å
306	T	97.8	Very high	97.5	Very high	19 Å²	19	49.8 Å²	49.8	12%	0.117	28%	0.283	C	S	.	.	H	α-helix	trans	-66.3	-42.9	177.6	-55.8	0	0	0	0	111.5	H287 F302 T303 S304 I308 I309 A356	H287-T306 VanDerWaalsContact ND1-CG2 3.31Å; H287-T306 WeakPolarHBondContact ND1-CG2 3.17Å; H287-T306 PolarHBondContact ND1-OG1 3.47Å; F302-T306 WeakPolarHBondContact O-CB 3.14Å; F302-T306 PolarHBondContact O-N 3.49Å; F302-T306 PolarHBondContact O-OG1 3.06Å; T303-T306 PolarHBondContact O-N 2.91Å; S304-T306 PolarHBondContact O-N 3.42Å; T306-I308 VanDerWaalsContact C-N 3.28Å; T306-I308 PolarHBondContact O-N 3.42Å; T306-I309 WeakPolarHBondContact O-CB 3.34Å; T306-I309 PolarHBondContact O-N 2.7Å; T306-A356 HydrophobicContact CG2-CB 3.55Å
307	M	97.6	Very high	97.7	Very high	64 Å²	64	45.8 Å²	45.8	32%	0.315	26%	0.259	S	S	.	.	H	α-helix	trans	-63.4	-32.2	177.7	-72.1	-179.2	179.8	0	0	112.9	T303 S304 I309 A310 A356 N357	T303-M307 HydrophobicContact CG2-CE 3.79Å; T303-M307 HydrophobicContact CG2-SD 4.18Å; T303-M307 WeakPolarHBondContact O-CG 3.4Å; T303-M307 PolarHBondContact O-N 3.02Å; S304-M307 PolarHBondContact O-N 3.47Å; M307-I309 PolarHBondContact O-N 2.9Å; M307-A310 VanDerWaalsContact O-CB 3.23Å; M307-A310 WeakPolarHBondContact O-CB 3.41Å; M307-A310 PolarHBondContact O-N 2.78Å; M307-A310 VanDerWaalsContact O-N 3.08Å; M307-A356 HydrophobicContact CE-CB 4.41Å; M307-A356 HydrophobicContact CG-CB 3.91Å; M307-N357 HydrophobicContact CE-CB 3.76Å
308	I	97.8	Very high	97.7	Very high	85 Å²	85	46.5 Å²	46.5	44%	0.436	26%	0.256	S	S	.	.	H	α-helix	trans	-59.8	-30	176.9	-72.4	166.2	0	0	0	111.8	L280 S304 A305 T306 A310 I311 P312	L280-I308 HydrophobicContact CD1-CG2 4.01Å; S304-I308 WeakPolarHBondContact O-CG1 3.49Å; S304-I308 PolarHBondContact O-N 2.95Å; S304-I308 VanDerWaalsContact O-N 3.11Å; A305-I308 PolarHBondContact O-N 2.98Å; T306-I308 VanDerWaalsContact C-N 3.28Å; T306-I308 PolarHBondContact O-N 3.42Å; I308-A310 PolarHBondContact O-N 3.1Å; I308-A310 VanDerWaalsContact O-N 3.16Å; I308-I311 WeakPolarHBondContact O-CB 3.33Å; I308-I311 PolarHBondContact O-N 3.15Å; I308-P312 VanDerWaalsContact O-CD 3.24Å; I308-P312 WeakPolarHBondContact O-CD 3.42Å
309	I	97.1	Very high	97.8	Very high	7 Å²	7	44.8 Å²	44.8	4%	0.036	25%	0.246	C	C	.	.	T	Hydrogen-bonded Turn	trans	-62.7	-23.6	178.7	-58.4	-178.9	0	0	0	112.3	Y241 I277 L280 V284 T306 M307 I311 P312 T313	Y241-I309 HydrophobicContact CE1-CG2 4.37Å; Y241-I309 HydrophobicContact CE2-CD1 4.13Å; Y241-I309 WeakPolarHBondContact OH-CD1 3.49Å; Y241-I309 WeakPolarHBondContact OH-CG2 3.36Å; I277-I309 HydrophobicContact CG1-CG2 4.4Å; L280-I309 HydrophobicContact CB-CD1 3.94Å; L280-I309 HydrophobicContact CB-CG1 3.77Å; L280-I309 HydrophobicContact CD1-CG1 3.9Å; L280-I309 HydrophobicContact CG-CG1 4.44Å; V284-I309 HydrophobicContact CB-CD1 4.22Å; V284-I309 HydrophobicContact CG1-CD1 3.75Å; V284-I309 HydrophobicContact CG1-CG1 4.47Å; V284-I309 HydrophobicContact CG2-CD1 3.65Å; T306-I309 WeakPolarHBondContact O-CB 3.34Å; T306-I309 PolarHBondContact O-N 2.7Å; M307-I309 PolarHBondContact O-N 2.9Å; I309-I311 PolarHBondContact O-N 3.45Å; I309-P312 VanDerWaalsContact O-CD 3.27Å; I309-P312 WeakPolarHBondContact O-CD 3.3Å; I309-P312 WeakPolarHBondContact O-CG 3.26Å; I309-T313 WeakPolarHBondContact O-CB 3.22Å; I309-T313 PolarHBondContact O-N 3.04Å; I309-T313 PolarHBondContact O-OG1 3.44Å
310	A	97.1	Very high	97.8	Very high	39 Å²	39	42.1 Å²	42.1	32%	0.322	24%	0.236	S	C	.	.	H	α-helix	trans	-60.9	-26.6	174.2	0	0	0	0	0	112.5	M307 I308 G314 I353	M307-A310 VanDerWaalsContact O-CB 3.23Å; M307-A310 WeakPolarHBondContact O-CB 3.41Å; M307-A310 PolarHBondContact O-N 2.78Å; M307-A310 VanDerWaalsContact O-N 3.08Å; I308-A310 PolarHBondContact O-N 3.1Å; I308-A310 VanDerWaalsContact O-N 3.16Å; A310-G314 WeakPolarHBondContact O-CA 3.11Å; A310-G314 PolarHBondContact O-N 3.18Å; A310-I353 HydrophobicContact CB-CD1 3.79Å; A310-I353 HydrophobicContact CB-CG1 4.1Å
311	I	98.3	Very high	97.8	Very high	115 Å²	115	43.7 Å²	43.7	59%	0.59	24%	0.237	S	C	*	.	H	α-helix	trans	-67.7	-62.2	-179.5	-59.2	173	0	0	0	111.7	I308 I309 T313 G314 V315	I308-I311 WeakPolarHBondContact O-CB 3.33Å; I308-I311 PolarHBondContact O-N 3.15Å; I309-I311 PolarHBondContact O-N 3.45Å; I311-T313 PolarHBondContact O-N 3.38Å; I311-G314 PolarHBondContact O-N 3.2Å; I311-G314 VanDerWaalsContact O-N 3.1Å; I311-V315 WeakPolarHBondContact O-CG2 3.3Å; I311-V315 PolarHBondContact O-N 3.13Å
312	P	98.3	Very high	97.8	Very high	11 Å²	11	39.7 Å²	39.7	7%	0.071	23%	0.228	C	C	.	.	H	α-helix	trans	-62.9	-32.1	178.8	25.3	-34.8	0	0	0	112.2	A273 I277 L280 I308 I309 V315 K316	A273-P312 HydrophobicContact CB-CB 3.89Å; A273-P312 WeakPolarHBondContact CB-O 3.15Å; I277-P312 HydrophobicContact CD1-CB 4.34Å; I277-P312 HydrophobicContact CG1-CB 3.97Å; I277-P312 HydrophobicContact CG1-CG 3.82Å; L280-P312 HydrophobicContact CD1-CG 4.4Å; I308-P312 VanDerWaalsContact O-CD 3.24Å; I308-P312 WeakPolarHBondContact O-CD 3.42Å; I309-P312 VanDerWaalsContact O-CD 3.27Å; I309-P312 WeakPolarHBondContact O-CD 3.3Å; I309-P312 WeakPolarHBondContact O-CG 3.26Å; P312-V315 PolarHBondContact O-N 3.09Å; P312-K316 PolarHBondContact O-N 3.05Å
313	T	97.3	Very high	97.7	Very high	28 Å²	28	39 Å²	39	17%	0.172	23%	0.225	C	C	.	.	H	α-helix	trans	-63.3	-45.4	173.1	-55	0	0	0	0	111.3	I309 I311 K316 V317 F345	I309-T313 WeakPolarHBondContact O-CB 3.22Å; I309-T313 PolarHBondContact O-N 3.04Å; I309-T313 PolarHBondContact O-OG1 3.44Å; I311-T313 PolarHBondContact O-N 3.38Å; T313-K316 WeakPolarHBondContact O-CB 3.34Å; T313-K316 PolarHBondContact O-N 3.5Å; T313-V317 PolarHBondContact O-N 3.22Å; T313-V317 VanDerWaalsContact O-N 3.11Å; T313-F345 HydrophobicContact CG2-CE1 3.59Å; T313-F345 HydrophobicContact CG2-CZ 4.11Å
314	G	97.6	Very high	97.5	Very high	19 Å²	19	39.3 Å²	39.3	20%	0.196	23%	0.226	C	C	.	.	H	α-helix	trans	-60.7	-43.4	175.4	0	0	0	0	0	112.6	A310 I311 K316 V317 F318	A310-G314 WeakPolarHBondContact O-CA 3.11Å; A310-G314 PolarHBondContact O-N 3.18Å; I311-G314 PolarHBondContact O-N 3.2Å; I311-G314 VanDerWaalsContact O-N 3.1Å; G314-K316 PolarHBondContact O-N 3.35Å; G314-V317 PolarHBondContact O-N 3.37Å; G314-V317 VanDerWaalsContact O-N 3.12Å; G314-F318 WeakPolarHBondContact O-CD2 3.37Å; G314-F318 PolarHBondContact O-N 2.87Å
315	V	98.2	Very high	97.4	Very high	59 Å²	59	43.3 Å²	43.3	36%	0.358	24%	0.237	S	C	.	.	H	α-helix	trans	-51.9	-45.4	174.5	170.8	0	0	0	0	110.8	A273 I311 P312 S319	A273-V315 HydrophobicContact CB-CB 4.39Å; A273-V315 HydrophobicContact CB-CG1 4.3Å; I311-V315 WeakPolarHBondContact O-CG2 3.3Å; I311-V315 PolarHBondContact O-N 3.13Å; P312-V315 PolarHBondContact O-N 3.09Å; V315-S319 VanDerWaalsContact O-CB 3.31Å; V315-S319 WeakPolarHBondContact O-CB 3.3Å; V315-S319 PolarHBondContact O-N 3.05Å; V315-S319 PolarHBondContact O-OG 2.66Å
316	K	98.1	Very high	97	Very high	1 Å²	1	46.6 Å²	46.6	0%	0.004	27%	0.272	C	S	.	.	H	α-helix	trans	-66.4	-44.8	178.5	-67.1	176.6	64.6	103.5	0	112.8	F248 A273 M274 I277 P312 T313 G314 F318 S319 W320	F248-K316 VanDerWaalsContact CB-CE 3.41Å; F248-K316 VanDerWaalsContact CB-NZ 3.27Å; F248-K316 HydrophobicContact CD2-CD 4.11Å; F248-K316 HydrophobicContact CE2-CD 4.43Å; F248-K316 VanDerWaalsContact CG-CE 3.43Å; A273-K316 HydrophobicContact CB-CD 4.2Å; A273-K316 HydrophobicContact CB-CG 3.82Å; M274-K316 HydrophobicContact CG-CD 4.18Å; M274-K316 PolarHBondContact SD-NZ 3.16Å; I277-K316 HydrophobicContact CD1-CD 4.08Å; P312-K316 PolarHBondContact O-N 3.05Å; T313-K316 WeakPolarHBondContact O-CB 3.34Å; T313-K316 PolarHBondContact O-N 3.5Å; G314-K316 PolarHBondContact O-N 3.35Å; K316-F318 PolarHBondContact O-N 3.32Å; K316-S319 WeakPolarHBondContact O-CB 3.28Å; K316-S319 PolarHBondContact O-N 3.15Å; K316-W320 HydrophobicContact CB-CH2 3.97Å; K316-W320 HydrophobicContact CB-CZ2 4.27Å; K316-W320 HydrophobicContact CB-CZ3 4.2Å; K316-W320 VanDerWaalsContact O-CD2 3.31Å; K316-W320 PolarHBondContact O-N 3.33Å
317	V	98.1	Very high	96.6	Very high	15 Å²	15	47 Å²	47	9%	0.091	28%	0.276	C	S	.	.	H	α-helix	trans	-58.4	-48.4	177	172.5	0	0	0	0	110.8	T313 G314 S319 W320 L321 I342	T313-V317 PolarHBondContact O-N 3.22Å; T313-V317 VanDerWaalsContact O-N 3.11Å; G314-V317 PolarHBondContact O-N 3.37Å; G314-V317 VanDerWaalsContact O-N 3.12Å; V317-S319 PolarHBondContact O-N 2.92Å; V317-W320 HydrophobicContact CG2-CE3 4.28Å; V317-W320 HydrophobicContact CG2-CZ3 3.99Å; V317-W320 PolarHBondContact O-N 3.2Å; V317-L321 HydrophobicContact CG1-CD1 4.37Å; V317-L321 WeakPolarHBondContact O-CG 3.41Å; V317-L321 PolarHBondContact O-N 3.49Å; V317-L321 VanDerWaalsContact O-N 3.11Å; V317-I342 HydrophobicContact CG1-CG2 4.27Å
318	F	98.3	Very high	96	Very high	142 Å²	142	51.6 Å²	51.6	62%	0.623	30%	0.301	S	S	*	.	H	α-helix	trans	-66.1	-37.2	177.3	-68.2	-58.6	0	0	0	112.6	G314 K316 W320 L321 A322	G314-F318 WeakPolarHBondContact O-CD2 3.37Å; G314-F318 PolarHBondContact O-N 2.87Å; K316-F318 PolarHBondContact O-N 3.32Å; F318-W320 PolarHBondContact O-N 3.24Å; F318-L321 PolarHBondContact O-N 3.46Å; F318-A322 VanDerWaalsContact O-CB 3.3Å; F318-A322 WeakPolarHBondContact O-CB 3.37Å; F318-A322 PolarHBondContact O-N 3.4Å
319	S	98.3	Very high	95.4	Very high	8 Å²	8	49.2 Å²	49.2	6%	0.056	29%	0.288	C	S	.	.	H	α-helix	trans	-61.1	-41.4	173.1	-83.8	0	0	0	0	112.6	F265 V315 K316 V317 A322 T323	F265-S319 VanDerWaalsContact O-CB 3.27Å; F265-S319 WeakPolarHBondContact O-CB 3.38Å; F265-S319 PolarHBondContact O-OG 3.21Å; V315-S319 VanDerWaalsContact O-CB 3.31Å; V315-S319 WeakPolarHBondContact O-CB 3.3Å; V315-S319 PolarHBondContact O-N 3.05Å; V315-S319 PolarHBondContact O-OG 2.66Å; K316-S319 WeakPolarHBondContact O-CB 3.28Å; K316-S319 PolarHBondContact O-N 3.15Å; V317-S319 PolarHBondContact O-N 2.92Å; S319-A322 PolarHBondContact O-N 2.64Å; S319-T323 WeakPolarHBondContact O-CB 3.4Å; S319-T323 PolarHBondContact O-N 2.83Å; S319-T323 PolarHBondContact O-OG1 2.95Å
320	W	98.1	Very high	94.7	Very high	1 Å²	1	53.9 Å²	53.9	0%	0.004	31%	0.309	C	S	.	.	H	α-helix	trans	-63.7	-46.1	174.5	-67	-46	0	0	0	111.7	F248 I251 S252 M270 K316 V317 F318 A322 T323 L324 F341 I342	F248-W320 HydrophobicContact CB-CH2 4.09Å; F248-W320 HydrophobicContact CB-CZ2 3.89Å; F248-W320 AromaticContact CD1-CH2 3.46Å; F248-W320 HydrophobicContact CD1-CH2 3.46Å; F248-W320 VanDerWaalsContact CD1-CH2 3.46Å; F248-W320 HydrophobicContact CD1-CZ2 4.12Å; F248-W320 HydrophobicContact CD1-CZ3 4.46Å; F248-W320 HydrophobicContact CE1-CH2 4.04Å; F248-W320 AromaticContact CG-CH2 3.96Å; F248-W320 HydrophobicContact CG-CH2 3.96Å; F248-W320 HydrophobicContact CG-CZ2 4.28Å; I251-W320 HydrophobicContact CB-CZ2 4.47Å; I251-W320 HydrophobicContact CG2-CD2 4.09Å; I251-W320 HydrophobicContact CG2-CG 4.39Å; I251-W320 HydrophobicContact CG2-CZ2 4.31Å; S252-W320 PolarHBondContact OG-NE1 3.29Å; M270-W320 HydrophobicContact CE-CZ2 4.34Å; K316-W320 HydrophobicContact CB-CH2 3.97Å; K316-W320 HydrophobicContact CB-CZ2 4.27Å; K316-W320 HydrophobicContact CB-CZ3 4.2Å; K316-W320 VanDerWaalsContact O-CD2 3.31Å; K316-W320 PolarHBondContact O-N 3.33Å; V317-W320 HydrophobicContact CG2-CE3 4.28Å; V317-W320 HydrophobicContact CG2-CZ3 3.99Å; V317-W320 PolarHBondContact O-N 3.2Å; F318-W320 PolarHBondContact O-N 3.24Å; W320-A322 VanDerWaalsContact C-N 3.34Å; W320-A322 PolarHBondContact O-N 3.11Å; W320-T323 WeakPolarHBondContact O-CB 3.28Å; W320-T323 PolarHBondContact O-N 3.5Å; W320-T323 VanDerWaalsContact O-N 3.12Å; W320-L324 WeakPolarHBondContact O-CG 3.4Å; W320-L324 PolarHBondContact O-N 2.84Å; W320-F341 AromaticContact CH2-CE1 3.98Å; W320-F341 HydrophobicContact CH2-CE1 3.98Å; W320-F341 AromaticContact CZ3-CE1 3.91Å; W320-F341 HydrophobicContact CZ3-CE1 3.91Å; W320-I342 HydrophobicContact CB-CD1 3.71Å; W320-I342 HydrophobicContact CB-CG1 4.39Å; W320-I342 HydrophobicContact CD2-CG1 4.41Å; W320-I342 HydrophobicContact CE3-CD1 4.5Å; W320-I342 HydrophobicContact CE3-CG1 3.94Å; W320-I342 HydrophobicContact CG-CD1 4.25Å
321	L	97.5	Very high	94.4	Very high	81 Å²	81	59.2 Å²	59.2	42%	0.424	32%	0.321	S	S	.	.	H	α-helix	trans	-61.4	-42	177.5	-65.7	176.2	0	0	0	112	V317 F318 T323 L324 H325 I342	V317-L321 HydrophobicContact CG1-CD1 4.37Å; V317-L321 WeakPolarHBondContact O-CG 3.41Å; V317-L321 PolarHBondContact O-N 3.49Å; V317-L321 VanDerWaalsContact O-N 3.11Å; F318-L321 PolarHBondContact O-N 3.46Å; L321-T323 VanDerWaalsContact C-N 3.31Å; L321-T323 PolarHBondContact O-N 2.76Å; L321-L324 PolarHBondContact O-N 2.74Å; L321-H325 WeakPolarHBondContact O-CB 3.17Å; L321-H325 PolarHBondContact O-N 3.34Å; L321-I342 HydrophobicContact CD2-CG2 4.22Å
322	A	97.3	Very high	94.2	Very high	32 Å²	32	54.4 Å²	54.4	26%	0.264	30%	0.297	S	S	.	.	H	α-helix	trans	-66.3	-32.8	174.7	0	0	0	0	0	112.5	K261 F265 F318 S319 W320 H325	K261-A322 PolarHBondContact NZ-O 3.2Å; F265-A322 HydrophobicContact CB-CB 3.83Å; F265-A322 HydrophobicContact CD1-CB 3.52Å; F265-A322 HydrophobicContact CD2-CB 4.22Å; F265-A322 HydrophobicContact CE1-CB 4.12Å; F265-A322 HydrophobicContact CG-CB 3.58Å; F318-A322 VanDerWaalsContact O-CB 3.3Å; F318-A322 WeakPolarHBondContact O-CB 3.37Å; F318-A322 PolarHBondContact O-N 3.4Å; S319-A322 PolarHBondContact O-N 2.64Å; W320-A322 VanDerWaalsContact C-N 3.34Å; W320-A322 PolarHBondContact O-N 3.11Å; A322-H325 PolarHBondContact O-N 3.06Å
323	T	95.9	Very high	94.1	Very high	0 Å²	0	53.9 Å²	53.9	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-66.9	-39.5	173.4	-54.1	0	0	0	0	111	V255 K261 P264 F265 S319 W320 L321	V255-T323 HydrophobicContact CG1-CG2 3.72Å; K261-T323 HydrophobicContact CD-CG2 4.04Å; K261-T323 VanDerWaalsContact CD-O 3.29Å; K261-T323 WeakPolarHBondContact CD-O 3.27Å; K261-T323 WeakPolarHBondContact CE-O 3.41Å; K261-T323 PolarHBondContact NZ-O 3.14Å; P264-T323 HydrophobicContact CB-CG2 4.44Å; F265-T323 PolarHBondContact N-OG1 3.4Å; S319-T323 WeakPolarHBondContact O-CB 3.4Å; S319-T323 PolarHBondContact O-N 2.83Å; S319-T323 PolarHBondContact O-OG1 2.95Å; W320-T323 WeakPolarHBondContact O-CB 3.28Å; W320-T323 PolarHBondContact O-N 3.5Å; W320-T323 VanDerWaalsContact O-N 3.12Å; L321-T323 VanDerWaalsContact C-N 3.31Å; L321-T323 PolarHBondContact O-N 2.76Å
324	L	94.8	Very high	94.1	Very high	22 Å²	22	52.6 Å²	52.6	12%	0.115	29%	0.286	C	S	.	.	H	α-helix	trans	-72.1	-32.6	175.9	-63.1	162.6	0	0	0	112.1	V255 W320 L321 G326 S327 M329 L339 I342	V255-L324 HydrophobicContact CB-CD2 4.46Å; V255-L324 HydrophobicContact CG1-CD1 4.46Å; V255-L324 HydrophobicContact CG1-CD2 3.77Å; V255-L324 HydrophobicContact CG1-CG 3.75Å; V255-L324 HydrophobicContact CG2-CD2 4.35Å; W320-L324 WeakPolarHBondContact O-CG 3.4Å; W320-L324 PolarHBondContact O-N 2.84Å; L321-L324 PolarHBondContact O-N 2.74Å; L324-G326 PolarHBondContact O-N 2.79Å; L324-S327 WeakPolarHBondContact O-CB 3.35Å; L324-S327 PolarHBondContact O-N 2.95Å; L324-S327 PolarHBondContact O-OG 2.87Å; L324-M329 HydrophobicContact CB-SD 4.34Å; L324-M329 HydrophobicContact CD2-SD 3.35Å; L324-M329 WeakPolarHBondContact CD2-SD 3.36Å; L324-M329 HydrophobicContact CG-SD 4.39Å; L324-L339 HydrophobicContact CD1-CD2 3.67Å; L324-I342 HydrophobicContact CD1-CD1 4.2Å
325	H	94.8	Very high	94	Very high	153 Å²	153	51.9 Å²	51.9	71%	0.708	28%	0.277	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.7	132.9	-177.5	-175.8	-99.8	0	0	0	112.6	K261 L321 A322 S327	K261-H325 PolarHBondContact NZ-O 3.42Å; L321-H325 WeakPolarHBondContact O-CB 3.17Å; L321-H325 PolarHBondContact O-N 3.34Å; A322-H325 PolarHBondContact O-N 3.06Å; H325-S327 PolarHBondContact O-N 3.25Å
326	G	90.1	Very high	94	Very high	78 Å²	78	50.9 Å²	50.9	80%	0.804	27%	0.27	S	S	*	.	T	Hydrogen-bonded Turn	trans	69.8	10.4	179.5	0	0	0	0	0	115.2	L324	L324-G326 PolarHBondContact O-N 2.79Å
327	S	88.9	Confident	94	Very high	28 Å²	28	50.9 Å²	50.9	20%	0.196	27%	0.27	C	S	.	.			trans	-91.4	149.9	176.6	70.6	0	0	0	0	112.3	S259 L324 H325 M329	S259-S327 WeakPolarHBondContact O-CB 3.23Å; L324-S327 WeakPolarHBondContact O-CB 3.35Å; L324-S327 PolarHBondContact O-N 2.95Å; L324-S327 PolarHBondContact O-OG 2.87Å; H325-S327 PolarHBondContact O-N 3.25Å; S327-M329 PolarHBondContact O-N 3.48Å; S327-M329 WeakPolarHBondContact OG-CG 3.48Å
328	N	85.3	Confident	94	Very high	159 Å²	159	50.2 Å²	50.2	85%	0.85	27%	0.266	S	S	*	.			trans	-87.5	82.8	168.9	-173.4	12	0	0	0	109.2
329	M	84.1	Confident	94	Very high	35 Å²	35	46 Å²	46	17%	0.172	25%	0.25	C	C	.	.			trans	-69.1	133.7	-171.2	-68.3	-153.6	-57.5	0	0	113.6	L324 S327 W331 V335	L324-M329 HydrophobicContact CB-SD 4.34Å; L324-M329 HydrophobicContact CD2-SD 3.35Å; L324-M329 WeakPolarHBondContact CD2-SD 3.36Å; L324-M329 HydrophobicContact CG-SD 4.39Å; S327-M329 PolarHBondContact O-N 3.48Å; S327-M329 WeakPolarHBondContact OG-CG 3.48Å; M329-W331 HydrophobicContact CE-CE3 4.41Å; M329-W331 HydrophobicContact CE-CH2 3.32Å; M329-W331 HydrophobicContact CE-CZ2 3.47Å; M329-W331 VanDerWaalsContact CE-CZ2 3.47Å; M329-W331 HydrophobicContact CE-CZ3 3.83Å; M329-V335 HydrophobicContact SD-CG1 4.3Å
330	K	82.4	Confident	94	Very high	106 Å²	106	45.7 Å²	45.7	46%	0.461	25%	0.248	S	C	.	.			trans	-83.5	112.4	163.9	-66.5	-177.8	-176.3	176.6	0	109.6	Y258 S332 E483	Y258-K330 HydrophobicContact CD1-CB 4.31Å; K330-S332 PolarHBondContact O-N 3.26Å; K330-E483 IonicContact NZ-OE1 3.07Å; K330-E483 PolarHBondContact NZ-OE1 2.87Å; K330-E483 IonicContact NZ-OE2 2.79Å; K330-E483 PolarHBondContact NZ-OE2 3.25Å
331	W	90.6	Very high	94	Very high	151 Å²	151	45.7 Å²	45.7	57%	0.572	25%	0.248	S	C	*	.			trans	-74	68.9	179.6	-65.6	101.7	0	0	0	112.9	M329 V335 L336 L339 K408	M329-W331 HydrophobicContact CE-CE3 4.41Å; M329-W331 HydrophobicContact CE-CH2 3.32Å; M329-W331 HydrophobicContact CE-CZ2 3.47Å; M329-W331 VanDerWaalsContact CE-CZ2 3.47Å; M329-W331 HydrophobicContact CE-CZ3 3.83Å; W331-V335 HydrophobicContact CE3-CG1 4.43Å; W331-L336 HydrophobicContact CE3-CD2 4.16Å; W331-L336 HydrophobicContact CZ3-CD2 4.43Å; W331-L339 HydrophobicContact CH2-CD1 4.13Å; W331-L339 HydrophobicContact CZ3-CD1 3.55Å; W331-K408 WeakPolarHBondContact O-CE 3.43Å; W331-K408 PolarHBondContact O-NZ 2.88Å
332	S	93.8	Very high	94	Very high	14 Å²	14	42.3 Å²	42.3	10%	0.098	23%	0.231	C	C	.	.			trans	-81.9	163.8	171.2	74.1	0	0	0	0	111.2	Y258 K330 A334 V335 L336	Y258-S332 WeakPolarHBondContact CD1-OG 3.48Å; Y258-S332 WeakPolarHBondContact CE1-OG 3.23Å; Y258-S332 VanDerWaalsContact CZ-OG 3.22Å; K330-S332 PolarHBondContact O-N 3.26Å; S332-A334 VanDerWaalsContact C-N 3.28Å; S332-A334 PolarHBondContact O-N 3.09Å; S332-A334 PolarHBondContact OG-N 3Å; S332-V335 PolarHBondContact O-N 3.26Å; S332-V335 PolarHBondContact OG-N 2.96Å; S332-L336 PolarHBondContact O-N 3.2Å
333	A	96.9	Very high	94.1	Very high	0 Å²	0	46.5 Å²	46.5	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-59.8	-38	173.9	0	0	0	0	0	112.3	V335 L336 W337 I391 Q404 A407 K408	A333-V335 VanDerWaalsContact C-N 3.3Å; A333-V335 PolarHBondContact O-N 2.84Å; A333-L336 WeakPolarHBondContact O-CB 3.41Å; A333-L336 PolarHBondContact O-N 3.12Å; A333-W337 PolarHBondContact O-N 3.17Å; A333-I391 HydrophobicContact CB-CD1 4.4Å; A333-I391 HydrophobicContact CB-CG2 4.13Å; A333-Q404 VanDerWaalsContact N-OE1 3.15Å; A333-A407 HydrophobicContact CB-CB 3.46Å; A333-A407 VanDerWaalsContact CB-CB 3.46Å; A333-K408 HydrophobicContact CB-CG 4.17Å
334	A	96.6	Very high	94.2	Very high	0 Å²	0	46.5 Å²	46.5	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-59.6	-37.9	178.4	0	0	0	0	0	112.7	I254 Y258 S332 W337 A338 I391 H392	I254-A334 HydrophobicContact CG2-CB 4.06Å; Y258-A334 HydrophobicContact CD2-CB 4.42Å; Y258-A334 HydrophobicContact CE2-CB 3.57Å; S332-A334 VanDerWaalsContact C-N 3.28Å; S332-A334 PolarHBondContact O-N 3.09Å; S332-A334 PolarHBondContact OG-N 3Å; A334-W337 PolarHBondContact O-N 2.98Å; A334-A338 PolarHBondContact O-N 3.21Å; A334-I391 HydrophobicContact CB-CG2 4.16Å; A334-H392 HydrophobicContact CB-CB 4.22Å
335	V	96.2	Very high	94.3	Very high	4 Å²	4	46.1 Å²	46.1	2%	0.024	24%	0.241	C	C	.	.	H	α-helix	trans	-65.6	-39.6	174.2	175.8	0	0	0	0	111.5	Y258 M329 W331 S332 A333 W337 A338 L339	Y258-V335 HydrophobicContact CD1-CG2 3.96Å; Y258-V335 HydrophobicContact CD2-CG2 3.66Å; Y258-V335 HydrophobicContact CG-CG2 3.34Å; M329-V335 HydrophobicContact SD-CG1 4.3Å; W331-V335 HydrophobicContact CE3-CG1 4.43Å; S332-V335 PolarHBondContact O-N 3.26Å; S332-V335 PolarHBondContact OG-N 2.96Å; A333-V335 VanDerWaalsContact C-N 3.3Å; A333-V335 PolarHBondContact O-N 2.84Å; V335-W337 VanDerWaalsContact C-N 3.34Å; V335-W337 PolarHBondContact O-N 3.16Å; V335-A338 PolarHBondContact O-N 3.16Å; V335-L339 HydrophobicContact CG1-CD1 3.94Å; V335-L339 HydrophobicContact CG1-CG 4.22Å; V335-L339 WeakPolarHBondContact O-CG 3.35Å; V335-L339 PolarHBondContact O-N 3.44Å
336	L	97.9	Very high	94.4	Very high	39 Å²	39	41.2 Å²	41.2	20%	0.204	22%	0.222	C	C	.	.	H	α-helix	trans	-61.6	-43.6	176.3	-61.8	-179.2	0	0	0	111.4	W331 S332 A333 A338 L339 G340 K408 F411	W331-L336 HydrophobicContact CE3-CD2 4.16Å; W331-L336 HydrophobicContact CZ3-CD2 4.43Å; S332-L336 PolarHBondContact O-N 3.2Å; A333-L336 WeakPolarHBondContact O-CB 3.41Å; A333-L336 PolarHBondContact O-N 3.12Å; L336-A338 VanDerWaalsContact C-N 3.34Å; L336-A338 PolarHBondContact O-N 3.45Å; L336-L339 PolarHBondContact O-N 2.71Å; L336-G340 PolarHBondContact O-N 2.99Å; L336-K408 HydrophobicContact CD1-CB 4.32Å; L336-K408 HydrophobicContact CD1-CG 3.86Å; L336-F411 HydrophobicContact CB-CD1 3.66Å; L336-F411 HydrophobicContact CB-CD2 4.1Å; L336-F411 HydrophobicContact CB-CE1 3.78Å; L336-F411 HydrophobicContact CB-CE2 4.21Å; L336-F411 HydrophobicContact CB-CG 3.82Å; L336-F411 HydrophobicContact CB-CZ 4.05Å; L336-F411 HydrophobicContact CD1-CD1 3.88Å; L336-F411 HydrophobicContact CD1-CE1 4.38Å; L336-F411 HydrophobicContact CD1-CG 4.47Å; L336-F411 HydrophobicContact CG-CD1 4.35Å; L336-F411 WeakPolarHBondContact O-CE2 3.43Å; L336-F411 WeakPolarHBondContact O-CZ 3.33Å
337	W	98.4	Very high	94.8	Very high	0 Å²	0	39.3 Å²	39.3	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-60.9	-41.6	173.3	-74.3	101.3	0	0	0	112.4	A333 A334 V335 G340 F341 F384 M387 I391 H410 F411 M414	A333-W337 PolarHBondContact O-N 3.17Å; A334-W337 PolarHBondContact O-N 2.98Å; V335-W337 VanDerWaalsContact C-N 3.34Å; V335-W337 PolarHBondContact O-N 3.16Å; W337-G340 PolarHBondContact O-N 2.97Å; W337-F341 WeakPolarHBondContact O-CB 3.39Å; W337-F341 PolarHBondContact O-N 3.27Å; W337-F384 HydrophobicContact CE3-CB 4.1Å; W337-F384 AromaticContact CE3-CD1 3.58Å; W337-F384 HydrophobicContact CE3-CD1 3.58Å; W337-F384 HydrophobicContact CE3-CD2 4.24Å; W337-F384 AromaticContact CE3-CE1 3.95Å; W337-F384 HydrophobicContact CE3-CE1 3.95Å; W337-F384 AromaticContact CE3-CG 3.73Å; W337-F384 HydrophobicContact CE3-CG 3.73Å; W337-F384 HydrophobicContact CE3-CZ 4.43Å; W337-F384 HydrophobicContact CZ3-CB 4.49Å; W337-F384 AromaticContact CZ3-CD1 3.88Å; W337-F384 HydrophobicContact CZ3-CD1 3.88Å; W337-F384 AromaticContact CZ3-CD2 3.84Å; W337-F384 HydrophobicContact CZ3-CD2 3.84Å; W337-F384 AromaticContact CZ3-CE1 3.93Å; W337-F384 HydrophobicContact CZ3-CE1 3.93Å; W337-F384 AromaticContact CZ3-CE2 3.89Å; W337-F384 HydrophobicContact CZ3-CE2 3.89Å; W337-F384 AromaticContact CZ3-CG 3.83Å; W337-F384 HydrophobicContact CZ3-CG 3.83Å; W337-F384 AromaticContact CZ3-CZ 3.94Å; W337-F384 HydrophobicContact CZ3-CZ 3.94Å; W337-M387 HydrophobicContact CD2-CB 3.69Å; W337-M387 HydrophobicContact CE3-CB 3.61Å; W337-M387 HydrophobicContact CE3-CG 4.35Å; W337-M387 HydrophobicContact CG-CB 4.39Å; W337-M387 HydrophobicContact CH2-CB 3.87Å; W337-M387 HydrophobicContact CH2-CG 3.91Å; W337-M387 HydrophobicContact CZ2-CB 3.98Å; W337-M387 HydrophobicContact CZ2-CG 4.35Å; W337-M387 HydrophobicContact CZ3-CB 3.7Å; W337-M387 HydrophobicContact CZ3-CG 3.92Å; W337-I391 HydrophobicContact CG-CD1 4.45Å; W337-H410 AromaticContact CH2-CE1 3.87Å; W337-H410 AromaticContact CZ2-CE1 3.44Å; W337-H410 VanDerWaalsContact CZ2-CE1 3.44Å; W337-H410 WeakPolarHBondContact CZ2-CE1 3.25Å; W337-H410 AromaticContact CZ2-ND1 3.4Å; W337-H410 WeakPolarHBondContact CZ2-ND1 3.49Å; W337-F411 HydrophobicContact CD2-CB 4.49Å; W337-F411 AromaticContact CD2-CD2 3.71Å; W337-F411 HydrophobicContact CD2-CD2 3.71Å; W337-F411 AromaticContact CE2-CD2 3.86Å; W337-F411 HydrophobicContact CE3-CD2 4.03Å; W337-F411 AromaticContact CG-CD2 3.99Å; W337-F411 HydrophobicContact CG-CD2 3.99Å; W337-F411 VanDerWaalsContact CZ2-CA 3.5Å; W337-F411 HydrophobicContact CZ2-CB 4Å; W337-F411 HydrophobicContact CZ2-CD2 4.31Å; W337-F411 HydrophobicContact CZ3-CD2 4.49Å; W337-M414 HydrophobicContact CH2-CB 3.63Å; W337-M414 HydrophobicContact CH2-CG 3.7Å; W337-M414 HydrophobicContact CZ2-CB 4.41Å; W337-M414 HydrophobicContact CZ3-CB 4.38Å; W337-M414 HydrophobicContact CZ3-CG 4.09Å
338	A	97.9	Very high	95.2	Very high	2 Å²	2	38 Å²	38	2%	0.017	19%	0.185	C	C	.	.	H	α-helix	trans	-66.3	-40.2	177	0	0	0	0	0	113.1	I251 I254 V255 A334 V335 L336 F341 I342	I251-A338 HydrophobicContact CD1-CB 4.03Å; I251-A338 HydrophobicContact CG2-CB 4.44Å; I254-A338 HydrophobicContact CG2-CB 3.9Å; V255-A338 HydrophobicContact CG2-CB 4.12Å; A334-A338 PolarHBondContact O-N 3.21Å; V335-A338 PolarHBondContact O-N 3.16Å; L336-A338 VanDerWaalsContact C-N 3.34Å; L336-A338 PolarHBondContact O-N 3.45Å; A338-F341 WeakPolarHBondContact O-CB 3.47Å; A338-F341 PolarHBondContact O-N 3.07Å; A338-I342 VanDerWaalsContact O-CG1 3.25Å; A338-I342 WeakPolarHBondContact O-CG1 3.44Å; A338-I342 PolarHBondContact O-N 3.47Å
339	L	97.8	Very high	95.8	Very high	52 Å²	52	31.7 Å²	31.7	27%	0.272	16%	0.157	S	C	.	.	H	α-helix	trans	-68.8	-41.3	174.9	-69.1	173.6	0	0	0	111.7	L324 W331 V335 L336 F341 I342 F343	L324-L339 HydrophobicContact CD1-CD2 3.67Å; W331-L339 HydrophobicContact CH2-CD1 4.13Å; W331-L339 HydrophobicContact CZ3-CD1 3.55Å; V335-L339 HydrophobicContact CG1-CD1 3.94Å; V335-L339 HydrophobicContact CG1-CG 4.22Å; V335-L339 WeakPolarHBondContact O-CG 3.35Å; V335-L339 PolarHBondContact O-N 3.44Å; L336-L339 PolarHBondContact O-N 2.71Å; L339-F341 VanDerWaalsContact C-N 3.32Å; L339-F341 PolarHBondContact O-N 2.9Å; L339-I342 PolarHBondContact O-N 3.05Å; L339-F343 WeakPolarHBondContact O-CB 3.23Å; L339-F343 PolarHBondContact O-N 3Å
340	G	98.1	Very high	96.4	Very high	3 Å²	3	35 Å²	35	3%	0.031	18%	0.175	C	C	.	.	H	α-helix	trans	-59	-44.2	173.3	0	0	0	0	0	111.6	L336 W337 L344	L336-G340 PolarHBondContact O-N 2.99Å; W337-G340 PolarHBondContact O-N 2.97Å; G340-L344 VanDerWaalsContact O-CB 3.32Å; G340-L344 WeakPolarHBondContact O-CB 3.12Å; G340-L344 VanDerWaalsContact O-CG 3.23Å; G340-L344 WeakPolarHBondContact O-CG 3.45Å; G340-L344 PolarHBondContact O-N 3Å
341	F	98.4	Very high	97.1	Very high	0 Å²	0	30.8 Å²	30.8	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-56.4	-56.6	171.6	172.5	-86.3	0	0	0	111.2	I244 F248 I251 W320 W337 A338 L339 F343 L344 F345 G381 F384 A385	I244-F341 HydrophobicContact CD1-CE2 3.9Å; I244-F341 HydrophobicContact CD1-CZ 4.23Å; F248-F341 HydrophobicContact CD1-CE1 4.17Å; F248-F341 AromaticContact CD1-CZ 3.64Å; F248-F341 HydrophobicContact CD1-CZ 3.64Å; F248-F341 HydrophobicContact CE1-CE1 4.4Å; F248-F341 AromaticContact CE1-CZ 3.78Å; F248-F341 HydrophobicContact CE1-CZ 3.78Å; I251-F341 HydrophobicContact CB-CD1 4.24Å; I251-F341 HydrophobicContact CB-CE1 4.34Å; I251-F341 HydrophobicContact CD1-CB 3.93Å; I251-F341 HydrophobicContact CD1-CD1 4.12Å; I251-F341 HydrophobicContact CD1-CD2 4.37Å; I251-F341 HydrophobicContact CD1-CG 3.88Å; I251-F341 HydrophobicContact CG1-CB 4.31Å; I251-F341 HydrophobicContact CG1-CD1 3.56Å; I251-F341 HydrophobicContact CG1-CD2 4.08Å; I251-F341 HydrophobicContact CG1-CE1 3.84Å; I251-F341 HydrophobicContact CG1-CE2 4.3Å; I251-F341 HydrophobicContact CG1-CG 3.71Å; I251-F341 HydrophobicContact CG1-CZ 4.21Å; I251-F341 HydrophobicContact CG2-CD1 3.94Å; I251-F341 HydrophobicContact CG2-CE1 4.26Å; W320-F341 AromaticContact CH2-CE1 3.98Å; W320-F341 HydrophobicContact CH2-CE1 3.98Å; W320-F341 AromaticContact CZ3-CE1 3.91Å; W320-F341 HydrophobicContact CZ3-CE1 3.91Å; W337-F341 WeakPolarHBondContact O-CB 3.39Å; W337-F341 PolarHBondContact O-N 3.27Å; A338-F341 WeakPolarHBondContact O-CB 3.47Å; A338-F341 PolarHBondContact O-N 3.07Å; L339-F341 VanDerWaalsContact C-N 3.32Å; L339-F341 PolarHBondContact O-N 2.9Å; F341-F343 VanDerWaalsContact C-N 3.27Å; F341-F343 PolarHBondContact O-N 2.67Å; F341-L344 PolarHBondContact O-N 3.16Å; F341-F345 HydrophobicContact CE1-CB 4.31Å; F341-F345 HydrophobicContact CE1-CG 4.38Å; F341-F345 HydrophobicContact CE2-CB 4.49Å; F341-F345 HydrophobicContact CZ-CB 4.27Å; F341-F345 HydrophobicContact CZ-CD2 4.29Å; F341-F345 HydrophobicContact CZ-CG 4.09Å; F341-F345 WeakPolarHBondContact O-CA 3.43Å; F341-F345 WeakPolarHBondContact O-CB 3.3Å; F341-F345 PolarHBondContact O-N 2.9Å; F341-G381 WeakPolarHBondContact CD2-O 3.47Å; F341-G381 VanDerWaalsContact CE2-CA 3.48Å; F341-G381 VanDerWaalsContact CE2-O 3.25Å; F341-G381 WeakPolarHBondContact CE2-O 3.5Å; F341-F384 HydrophobicContact CB-CB 4.16Å; F341-F384 HydrophobicContact CD2-CB 4.41Å; F341-A385 HydrophobicContact CD2-CB 4.14Å; F341-A385 HydrophobicContact CE2-CB 4.18Å
342	I	98.4	Very high	97.5	Very high	10 Å²	10	24.3 Å²	24.3	5%	0.051	14%	0.138	C	C	.	.	H	α-helix	trans	-57.5	-44.1	-175.4	-68.8	163.9	0	0	0	110.4	I251 V255 V317 W320 L321 L324 A338 L339 T346	I251-I342 HydrophobicContact CG2-CD1 4.46Å; I251-I342 HydrophobicContact CG2-CG1 4.31Å; V255-I342 HydrophobicContact CG2-CD1 4.23Å; V317-I342 HydrophobicContact CG1-CG2 4.27Å; W320-I342 HydrophobicContact CB-CD1 3.71Å; W320-I342 HydrophobicContact CB-CG1 4.39Å; W320-I342 HydrophobicContact CD2-CG1 4.41Å; W320-I342 HydrophobicContact CE3-CD1 4.5Å; W320-I342 HydrophobicContact CE3-CG1 3.94Å; W320-I342 HydrophobicContact CG-CD1 4.25Å; L321-I342 HydrophobicContact CD2-CG2 4.22Å; L324-I342 HydrophobicContact CD1-CD1 4.2Å; A338-I342 VanDerWaalsContact O-CG1 3.25Å; A338-I342 WeakPolarHBondContact O-CG1 3.44Å; A338-I342 PolarHBondContact O-N 3.47Å; L339-I342 PolarHBondContact O-N 3.05Å; I342-T346 WeakPolarHBondContact O-CB 3.44Å; I342-T346 PolarHBondContact O-N 3.38Å; I342-T346 PolarHBondContact O-OG1 2.67Å
343	F	98.2	Very high	97.6	Very high	120 Å²	120	27 Å²	27	53%	0.526	15%	0.151	S	C	.	.	H	α-helix	trans	-65.4	-57.5	179.3	175.6	-110.7	0	0	0	112.3	L339 F341 T346 V347 F415	L339-F343 WeakPolarHBondContact O-CB 3.23Å; L339-F343 PolarHBondContact O-N 3Å; F341-F343 VanDerWaalsContact C-N 3.27Å; F341-F343 PolarHBondContact O-N 2.67Å; F343-T346 WeakPolarHBondContact O-CB 3.49Å; F343-T346 PolarHBondContact O-N 3Å; F343-T346 VanDerWaalsContact O-N 3.15Å; F343-V347 HydrophobicContact CE1-CG2 4.43Å; F343-V347 HydrophobicContact CE2-CG2 4.23Å; F343-V347 HydrophobicContact CZ-CG2 4.11Å; F343-V347 PolarHBondContact O-N 3.23Å; F343-F415 HydrophobicContact CD1-CE2 4.31Å; F343-F415 HydrophobicContact CD1-CZ 4.09Å; F343-F415 HydrophobicContact CE1-CZ 4.28Å
344	L	97.9	Very high	97.7	Very high	0 Å²	0	29.3 Å²	29.3	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-70.8	-36.5	-172.7	-61.7	169.6	0	0	0	111.8	G340 F341 T346 V347 G348 Y376 M380 F384 F415 N419	G340-L344 VanDerWaalsContact O-CB 3.32Å; G340-L344 WeakPolarHBondContact O-CB 3.12Å; G340-L344 VanDerWaalsContact O-CG 3.23Å; G340-L344 WeakPolarHBondContact O-CG 3.45Å; G340-L344 PolarHBondContact O-N 3Å; F341-L344 PolarHBondContact O-N 3.16Å; L344-T346 VanDerWaalsContact C-N 3.26Å; L344-T346 PolarHBondContact O-N 3.5Å; L344-V347 PolarHBondContact O-N 3.01Å; L344-G348 PolarHBondContact O-N 2.93Å; L344-Y376 HydrophobicContact CB-CD1 4.26Å; L344-Y376 HydrophobicContact CB-CE1 4.43Å; L344-Y376 HydrophobicContact CD2-CD1 4.43Å; L344-Y376 HydrophobicContact CD2-CE1 3.77Å; L344-Y376 WeakPolarHBondContact O-CD1 3.33Å; L344-M380 HydrophobicContact CB-CB 3.67Å; L344-M380 HydrophobicContact CB-CG 4.19Å; L344-M380 HydrophobicContact CB-SD 3.83Å; L344-M380 HydrophobicContact CD1-CB 3.98Å; L344-M380 HydrophobicContact CD1-CG 3.78Å; L344-M380 HydrophobicContact CD1-SD 3.65Å; L344-M380 HydrophobicContact CD2-SD 3.88Å; L344-M380 HydrophobicContact CG-CB 4.43Å; L344-M380 HydrophobicContact CG-SD 3.97Å; L344-F384 HydrophobicContact CD1-CD1 4.37Å; L344-F384 HydrophobicContact CD1-CE1 3.69Å; L344-F384 HydrophobicContact CD1-CZ 3.78Å; L344-F415 HydrophobicContact CD1-CD2 3.73Å; L344-F415 HydrophobicContact CD1-CE2 3.56Å; L344-F415 HydrophobicContact CD2-CE2 4.08Å; L344-F415 HydrophobicContact CD2-CZ 4.33Å; L344-F415 HydrophobicContact CG-CE2 3.88Å; L344-N419 VanDerWaalsContact CD2-ND2 3.33Å; L344-N419 WeakPolarHBondContact CD2-ND2 3.31Å; L344-N419 VanDerWaalsContact CD2-OD1 3.23Å; L344-N419 WeakPolarHBondContact CD2-OD1 3.4Å
345	F	97.8	Very high	97.7	Very high	15 Å²	15	30.1 Å²	30.1	7%	0.066	17%	0.169	C	C	.	.	H	α-helix	trans	-61.8	-36.7	172.5	-175.8	-99.2	0	0	0	111.5	I244 F248 T313 F341 G348 G349 V377	I244-F345 HydrophobicContact CD1-CD2 4.2Å; I244-F345 HydrophobicContact CD1-CE2 4.02Å; I244-F345 HydrophobicContact CG1-CD2 4.38Å; I244-F345 HydrophobicContact CG1-CE2 3.74Å; I244-F345 HydrophobicContact CG1-CZ 4.31Å; F248-F345 HydrophobicContact CE1-CD1 4.25Å; F248-F345 AromaticContact CE1-CE1 3.68Å; F248-F345 HydrophobicContact CE1-CE1 3.68Å; F248-F345 HydrophobicContact CE1-CE2 4.04Å; F248-F345 AromaticContact CE1-CZ 3.58Å; F248-F345 HydrophobicContact CE1-CZ 3.58Å; F248-F345 AromaticContact CZ-CE1 3.83Å; F248-F345 HydrophobicContact CZ-CE1 3.83Å; F248-F345 HydrophobicContact CZ-CE2 4.19Å; F248-F345 AromaticContact CZ-CZ 3.48Å; F248-F345 HydrophobicContact CZ-CZ 3.48Å; F248-F345 VanDerWaalsContact CZ-CZ 3.48Å; T313-F345 HydrophobicContact CG2-CE1 3.59Å; T313-F345 HydrophobicContact CG2-CZ 4.11Å; F341-F345 HydrophobicContact CE1-CB 4.31Å; F341-F345 HydrophobicContact CE1-CG 4.38Å; F341-F345 HydrophobicContact CE2-CB 4.49Å; F341-F345 HydrophobicContact CZ-CB 4.27Å; F341-F345 HydrophobicContact CZ-CD2 4.29Å; F341-F345 HydrophobicContact CZ-CG 4.09Å; F341-F345 WeakPolarHBondContact O-CA 3.43Å; F341-F345 WeakPolarHBondContact O-CB 3.3Å; F341-F345 PolarHBondContact O-N 2.9Å; F345-G348 PolarHBondContact O-N 2.99Å; F345-G349 PolarHBondContact O-N 3.14Å; F345-V377 HydrophobicContact CD2-CB 4.41Å; F345-V377 HydrophobicContact CD2-CG1 4.43Å; F345-V377 HydrophobicContact CE2-CB 4.16Å; F345-V377 HydrophobicContact CE2-CG1 4.24Å
346	T	97.8	Very high	97.8	Very high	50 Å²	50	30.1 Å²	30.1	31%	0.307	17%	0.169	S	C	.	.	H	α-helix	trans	-67.2	-43.6	174.7	-57.7	0	0	0	0	111.4	I342 F343 L344 G348 G349 L350	I342-T346 WeakPolarHBondContact O-CB 3.44Å; I342-T346 PolarHBondContact O-N 3.38Å; I342-T346 PolarHBondContact O-OG1 2.67Å; F343-T346 WeakPolarHBondContact O-CB 3.49Å; F343-T346 PolarHBondContact O-N 3Å; F343-T346 VanDerWaalsContact O-N 3.15Å; L344-T346 VanDerWaalsContact C-N 3.26Å; L344-T346 PolarHBondContact O-N 3.5Å; T346-G348 VanDerWaalsContact C-N 3.34Å; T346-G348 PolarHBondContact O-N 2.74Å; T346-G349 PolarHBondContact O-N 3.12Å; T346-L350 HydrophobicContact CG2-CD1 4.49Å; T346-L350 WeakPolarHBondContact O-CG 3.31Å; T346-L350 PolarHBondContact O-N 3.07Å
347	V	97.8	Very high	97.8	Very high	38 Å²	38	30.5 Å²	30.5	23%	0.23	17%	0.172	C	C	.	.	H	α-helix	trans	-58.6	-46.6	174	174.6	0	0	0	0	110.9	F343 L344 G349 L350 T351 Y376	F343-V347 HydrophobicContact CE1-CG2 4.43Å; F343-V347 HydrophobicContact CE2-CG2 4.23Å; F343-V347 HydrophobicContact CZ-CG2 4.11Å; F343-V347 PolarHBondContact O-N 3.23Å; L344-V347 PolarHBondContact O-N 3.01Å; V347-G349 PolarHBondContact O-N 3.27Å; V347-L350 PolarHBondContact O-N 3.25Å; V347-T351 PolarHBondContact O-N 3.36Å; V347-Y376 HydrophobicContact CB-CD1 4.17Å; V347-Y376 HydrophobicContact CB-CE1 4.26Å; V347-Y376 HydrophobicContact CG1-CD1 4.02Å; V347-Y376 HydrophobicContact CG1-CE1 3.9Å
348	G	97.2	Very high	97.7	Very high	0 Å²	0	31 Å²	31	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-58.8	-45.3	173.1	0	0	0	0	0	112.9	L344 F345 T346 L350 T351 G352 H373	L344-G348 PolarHBondContact O-N 2.93Å; F345-G348 PolarHBondContact O-N 2.99Å; T346-G348 VanDerWaalsContact C-N 3.34Å; T346-G348 PolarHBondContact O-N 2.74Å; G348-L350 PolarHBondContact O-N 2.93Å; G348-T351 PolarHBondContact O-N 3.03Å; G348-T351 PolarHBondContact O-OG1 3.44Å; G348-G352 PolarHBondContact O-N 2.91Å; G348-H373 PolarHBondContact O-CE1 3.2Å; G348-H373 PolarHBondContact O-ND1 2.93Å
349	G	96.8	Very high	97.6	Very high	26 Å²	26	35 Å²	35	27%	0.268	20%	0.203	S	C	.	.	H	α-helix	trans	-60.6	-42	177.7	0	0	0	0	0	112.9	F345 T346 V347 T351 G352 I353	F345-G349 PolarHBondContact O-N 3.14Å; T346-G349 PolarHBondContact O-N 3.12Å; V347-G349 PolarHBondContact O-N 3.27Å; G349-T351 PolarHBondContact O-N 3.36Å; G349-G352 WeakPolarHBondContact O-CA 3.27Å; G349-G352 PolarHBondContact O-N 3.47Å; G349-G352 VanDerWaalsContact O-N 3.11Å; G349-I353 WeakPolarHBondContact O-CG1 3.43Å; G349-I353 PolarHBondContact O-N 3.07Å
350	L	97.6	Very high	97.6	Very high	106 Å²	106	36.2 Å²	36.2	56%	0.555	21%	0.21	S	C	*	.	H	α-helix	trans	-63.5	-41.6	177.3	-68.9	174.7	0	0	0	112.1	T346 V347 G348 G352 I353 V354	T346-L350 HydrophobicContact CG2-CD1 4.49Å; T346-L350 WeakPolarHBondContact O-CG 3.31Å; T346-L350 PolarHBondContact O-N 3.07Å; V347-L350 PolarHBondContact O-N 3.25Å; G348-L350 PolarHBondContact O-N 2.93Å; L350-G352 VanDerWaalsContact C-N 3.25Å; L350-G352 PolarHBondContact O-N 3.15Å; L350-I353 HydrophobicContact CD2-CD1 4.36Å; L350-I353 PolarHBondContact O-N 3.14Å; L350-V354 PolarHBondContact O-N 3.32Å
351	T	98	Very high	97.5	Very high	17 Å²	17	36.4 Å²	36.4	10%	0.104	21%	0.21	C	C	.	.	H	α-helix	trans	-67.1	-29.3	174.1	60.6	0	0	0	0	112.1	V347 G348 G349 V354 L355 H373	V347-T351 PolarHBondContact O-N 3.36Å; G348-T351 PolarHBondContact O-N 3.03Å; G348-T351 PolarHBondContact O-OG1 3.44Å; G349-T351 PolarHBondContact O-N 3.36Å; T351-V354 WeakPolarHBondContact O-CB 3.32Å; T351-V354 PolarHBondContact O-N 3.25Å; T351-L355 PolarHBondContact O-N 3.46Å; T351-L355 VanDerWaalsContact O-N 3.13Å; T351-H373 PolarHBondContact OG1-ND1 2.9Å; T351-H373 VanDerWaalsContact OG1-ND1 3.12Å
352	G	97.1	Very high	97.4	Very high	15 Å²	15	40.9 Å²	40.9	16%	0.155	23%	0.233	C	C	.	.	H	α-helix	trans	-67.1	-36.5	172.1	0	0	0	0	0	113.4	G348 G349 L350 V354 L355 A356 H373	G348-G352 PolarHBondContact O-N 2.91Å; G349-G352 WeakPolarHBondContact O-CA 3.27Å; G349-G352 PolarHBondContact O-N 3.47Å; G349-G352 VanDerWaalsContact O-N 3.11Å; L350-G352 VanDerWaalsContact C-N 3.25Å; L350-G352 PolarHBondContact O-N 3.15Å; G352-V354 VanDerWaalsContact C-N 3.25Å; G352-V354 PolarHBondContact O-N 3.42Å; G352-L355 CarbonylContact O-C 3.42Å; G352-L355 PolarHBondContact O-N 3.25Å; G352-A356 WeakPolarHBondContact O-CB 3.32Å; G352-A356 PolarHBondContact O-N 3.47Å; G352-H373 WeakPolarHBondContact CA-CE1 3.38Å; G352-H373 WeakPolarHBondContact CA-ND1 3.31Å; G352-H373 PolarHBondContact N-CE1 3.39Å; G352-H373 PolarHBondContact N-ND1 3.43Å; G352-H373 VanDerWaalsContact N-ND1 3.13Å
353	I	97.1	Very high	97.3	Very high	69 Å²	69	45.4 Å²	45.4	35%	0.354	26%	0.26	S	S	.	.	H	α-helix	trans	-63.7	-35	173.6	-65.2	169.1	0	0	0	110.7	A310 G349 L350 A356	A310-I353 HydrophobicContact CB-CD1 3.79Å; A310-I353 HydrophobicContact CB-CG1 4.1Å; G349-I353 WeakPolarHBondContact O-CG1 3.43Å; G349-I353 PolarHBondContact O-N 3.07Å; L350-I353 HydrophobicContact CD2-CD1 4.36Å; L350-I353 PolarHBondContact O-N 3.14Å; I353-A356 PolarHBondContact O-N 2.97Å
354	V	98.1	Very high	97.3	Very high	49 Å²	49	40.2 Å²	40.2	30%	0.297	24%	0.238	S	C	.	.	H	α-helix	trans	-63.3	-48.2	172.9	179.7	0	0	0	0	110.4	L350 T351 G352 A356 N357 L360 L364 Y369	L350-V354 PolarHBondContact O-N 3.32Å; T351-V354 WeakPolarHBondContact O-CB 3.32Å; T351-V354 PolarHBondContact O-N 3.25Å; G352-V354 VanDerWaalsContact C-N 3.25Å; G352-V354 PolarHBondContact O-N 3.42Å; V354-A356 VanDerWaalsContact C-N 3.29Å; V354-A356 PolarHBondContact O-N 2.99Å; V354-N357 WeakPolarHBondContact O-CB 3.47Å; V354-N357 PolarHBondContact O-N 3.26Å; V354-L360 HydrophobicContact CG1-CD1 3.84Å; V354-L364 HydrophobicContact CG1-CD1 3.88Å; V354-Y369 HydrophobicContact CB-CE1 4.47Å; V354-Y369 HydrophobicContact CG1-CE1 4.39Å
355	L	98.1	Very high	97.3	Very high	17 Å²	17	42 Å²	42	9%	0.089	25%	0.246	C	C	.	.	H	α-helix	trans	-68.4	-25.1	178.5	-71	173.3	0	0	0	113.8	T351 G352 N357 L364 Y369 V370 H373	T351-L355 PolarHBondContact O-N 3.46Å; T351-L355 VanDerWaalsContact O-N 3.13Å; G352-L355 CarbonylContact O-C 3.42Å; G352-L355 PolarHBondContact O-N 3.25Å; L355-N357 PolarHBondContact O-N 2.82Å; L355-L364 HydrophobicContact CD2-CB 3.75Å; L355-L364 HydrophobicContact CD2-CD1 3.99Å; L355-Y369 HydrophobicContact CD1-CD1 4.05Å; L355-Y369 HydrophobicContact CD1-CE1 4.3Å; L355-Y369 HydrophobicContact CD2-CD1 3.76Å; L355-Y369 HydrophobicContact CD2-CE1 4.18Å; L355-Y369 HydrophobicContact CG-CD1 3.89Å; L355-Y369 HydrophobicContact CG-CE1 3.93Å; L355-V370 HydrophobicContact CD1-CB 4.39Å; L355-V370 HydrophobicContact CD1-CG2 4.03Å; L355-V370 HydrophobicContact CD2-CG2 3.76Å; L355-H373 HydrophobicContact CD1-CB 3.58Å
356	A	97.4	Very high	97.3	Very high	4 Å²	4	44.7 Å²	44.7	3%	0.033	26%	0.262	C	S	.	.	T	Hydrogen-bonded Turn	trans	-64.6	-17.4	174.5	0	0	0	0	0	112.4	T303 T306 M307 G352 I353 V354 S358	T303-A356 WeakPolarHBondContact CA-O 3.5Å; T303-A356 WeakPolarHBondContact CG2-O 3.44Å; T306-A356 HydrophobicContact CG2-CB 3.55Å; M307-A356 HydrophobicContact CE-CB 4.41Å; M307-A356 HydrophobicContact CG-CB 3.91Å; G352-A356 WeakPolarHBondContact O-CB 3.32Å; G352-A356 PolarHBondContact O-N 3.47Å; I353-A356 PolarHBondContact O-N 2.97Å; V354-A356 VanDerWaalsContact C-N 3.29Å; V354-A356 PolarHBondContact O-N 2.99Å; A356-S358 PolarHBondContact O-N 2.94Å
357	N	97.9	Very high	97.3	Very high	48 Å²	48	42.8 Å²	42.8	26%	0.257	25%	0.25	S	C	.	.			trans	-83.3	109.6	176.4	-171.7	-49.6	0	0	0	110.9	M307 V354 L355 S359 L360 D361	M307-N357 HydrophobicContact CE-CB 3.76Å; V354-N357 WeakPolarHBondContact O-CB 3.47Å; V354-N357 PolarHBondContact O-N 3.26Å; L355-N357 PolarHBondContact O-N 2.82Å; N357-S359 PolarHBondContact O-N 2.93Å; N357-S359 VanDerWaalsContact O-N 3.08Å; N357-S359 WeakPolarHBondContact OD1-CA 3.35Å; N357-S359 VanDerWaalsContact OD1-CB 3.29Å; N357-S359 WeakPolarHBondContact OD1-CB 3.31Å; N357-S359 PolarHBondContact OD1-N 2.89Å; N357-L360 HydrophobicContact CB-CB 4.19Å; N357-L360 HydrophobicContact CB-CD1 4.09Å; N357-L360 HydrophobicContact CB-CG 4.15Å; N357-L360 PolarHBondContact O-N 3.26Å; N357-L360 PolarHBondContact OD1-N 3.28Å; N357-D361 PolarHBondContact O-N 3.44Å
358	S	96.7	Very high	97.3	Very high	11 Å²	11	41.5 Å²	41.5	8%	0.077	24%	0.241	C	C	.	.	H	α-helix	trans	-57.8	-24.2	179.7	58.4	0	0	0	0	115.5	T303 A356 I362	T303-S358 VanDerWaalsContact OG1-CB 3.3Å; T303-S358 WeakPolarHBondContact OG1-CB 3.2Å; T303-S358 PolarHBondContact OG1-N 2.72Å; T303-S358 PolarHBondContact OG1-OG 2.99Å; A356-S358 PolarHBondContact O-N 2.94Å; S358-I362 WeakPolarHBondContact O-CG1 3.28Å
359	S	96.1	Very high	97.4	Very high	84 Å²	84	42.4 Å²	42.4	59%	0.587	25%	0.245	S	C	*	.	H	α-helix	trans	-77.6	-36.3	176.1	-57.2	0	0	0	0	112	N357	N357-S359 PolarHBondContact O-N 2.93Å; N357-S359 VanDerWaalsContact O-N 3.08Å; N357-S359 WeakPolarHBondContact OD1-CA 3.35Å; N357-S359 VanDerWaalsContact OD1-CB 3.29Å; N357-S359 WeakPolarHBondContact OD1-CB 3.31Å; N357-S359 PolarHBondContact OD1-N 2.89Å
360	L	97.2	Very high	97.5	Very high	79 Å²	79	42.5 Å²	42.5	41%	0.414	24%	0.24	S	C	.	.	H	α-helix	trans	-77.6	-34.8	175.2	-63.3	178.8	0	0	0	111.2	V354 N357 I362 V363 L364	V354-L360 HydrophobicContact CG1-CD1 3.84Å; N357-L360 HydrophobicContact CB-CB 4.19Å; N357-L360 HydrophobicContact CB-CD1 4.09Å; N357-L360 HydrophobicContact CB-CG 4.15Å; N357-L360 PolarHBondContact O-N 3.26Å; N357-L360 PolarHBondContact OD1-N 3.28Å; L360-I362 PolarHBondContact O-N 2.95Å; L360-V363 WeakPolarHBondContact O-CG2 3.3Å; L360-V363 PolarHBondContact O-N 2.9Å; L360-V363 VanDerWaalsContact O-N 3.13Å; L360-L364 HydrophobicContact CB-CD1 4.47Å; L360-L364 PolarHBondContact O-N 3.36Å
361	D	96.9	Very high	97.5	Very high	6 Å²	6	38.9 Å²	38.9	3%	0.032	22%	0.222	C	C	.	.	H	α-helix	trans	-61.8	-29.4	179.9	-162.5	52.9	0	0	0	111.6	F290 N357 V363 L364 H365	F290-D361 HydrophobicContact CB-CB 4.38Å; F290-D361 HydrophobicContact CD2-CB 3.83Å; N357-D361 PolarHBondContact O-N 3.44Å; D361-V363 PolarHBondContact O-N 3.4Å; D361-L364 PolarHBondContact O-N 2.94Å; D361-H365 WeakPolarHBondContact O-CA 3.28Å; D361-H365 WeakPolarHBondContact O-CB 3.39Å; D361-H365 PolarHBondContact O-N 2.87Å; D361-H365 IonicContact OD1-ND1 3.97Å; D361-H365 IonicContact OD2-CE1 3.98Å; D361-H365 IonicContact OD2-CG 3.69Å; D361-H365 IonicContact OD2-ND1 2.93Å; D361-H365 PolarHBondContact OD2-ND1 3.33Å
362	I	94.9	Very high	97.5	Very high	94 Å²	94	38 Å²	38	48%	0.482	22%	0.217	S	C	.	.	H	α-helix	trans	-51.5	-36.8	175.1	-67.7	164.4	0	0	0	112.9	S358 L360	S358-I362 WeakPolarHBondContact O-CG1 3.28Å; L360-I362 PolarHBondContact O-N 2.95Å
363	V	96.9	Very high	97.6	Very high	105 Å²	105	39 Å²	39	64%	0.636	22%	0.217	S	C	*	.	H	α-helix	trans	-97.1	-16.8	-179.7	-60.1	0	0	0	0	113.6	L360 D361	L360-V363 WeakPolarHBondContact O-CG2 3.3Å; L360-V363 PolarHBondContact O-N 2.9Å; L360-V363 VanDerWaalsContact O-N 3.13Å; D361-V363 PolarHBondContact O-N 3.4Å
364	L	98	Very high	97.5	Very high	12 Å²	12	38 Å²	38	6%	0.063	21%	0.211	C	C	.	.	H	α-helix	trans	-102	-19	-178	-61.5	178.1	0	0	0	113.2	V354 L355 L360 D361 T367 Y369 V370 L430	V354-L364 HydrophobicContact CG1-CD1 3.88Å; L355-L364 HydrophobicContact CD2-CB 3.75Å; L355-L364 HydrophobicContact CD2-CD1 3.99Å; L360-L364 HydrophobicContact CB-CD1 4.47Å; L360-L364 PolarHBondContact O-N 3.36Å; D361-L364 PolarHBondContact O-N 2.94Å; L364-T367 WeakPolarHBondContact O-CB 3.42Å; L364-T367 WeakPolarHBondContact O-CG2 3.39Å; L364-T367 PolarHBondContact O-N 2.86Å; L364-T367 VanDerWaalsContact O-N 3.13Å; L364-T367 PolarHBondContact O-OG1 3.13Å; L364-Y369 HydrophobicContact CD1-CD1 4Å; L364-Y369 HydrophobicContact CD1-CE1 4.09Å; L364-Y369 HydrophobicContact CD1-CG 4.36Å; L364-Y369 HydrophobicContact CD2-CD2 4.35Å; L364-Y369 HydrophobicContact CD2-CG 4.11Å; L364-V370 WeakPolarHBondContact O-CG2 3.36Å; L364-L430 HydrophobicContact CD2-CD2 4.03Å
365	H	98.1	Very high	97.5	Very high	36 Å²	36	37.5 Å²	37.5	17%	0.167	21%	0.205	C	C	.	.	T	Hydrogen-bonded Turn	trans	-58.4	141	-178.9	-162.6	87.8	0	0	0	110.6	H288 T291 D361 T367	H288-H365 PolarHBondContact O-CE1 2.99Å; T291-H365 HydrophobicContact CG2-CB 3.48Å; T291-H365 VanDerWaalsContact CG2-CB 3.48Å; T291-H365 VanDerWaalsContact CG2-CG 3.48Å; T291-H365 PolarHBondContact OG1-CD2 2.78Å; T291-H365 VanDerWaalsContact OG1-CD2 3.32Å; T291-H365 PolarHBondContact OG1-NE2 2.79Å; D361-H365 WeakPolarHBondContact O-CA 3.28Å; D361-H365 WeakPolarHBondContact O-CB 3.39Å; D361-H365 PolarHBondContact O-N 2.87Å; D361-H365 IonicContact OD1-ND1 3.97Å; D361-H365 IonicContact OD2-CE1 3.98Å; D361-H365 IonicContact OD2-CG 3.69Å; D361-H365 IonicContact OD2-ND1 2.93Å; D361-H365 PolarHBondContact OD2-ND1 3.33Å; H365-T367 PolarHBondContact O-N 3.35Å
366	D	97.3	Very high	97.5	Very high	72 Å²	72	36.7 Å²	36.7	39%	0.385	20%	0.201	S	C	.	.	T	Hydrogen-bonded Turn	trans	55	15.6	-176.3	-73.3	-35.4	0	0	0	115.6	P434 R435	D366-P434 CarbonylContact O-C 3.59Å; D366-P434 WeakPolarHBondContact O-CA 3.31Å; D366-R435 HydrophobicContact CB-CG 4.42Å; D366-R435 VanDerWaalsContact O-CG 3.3Å; D366-R435 WeakPolarHBondContact O-CG 3.29Å; D366-R435 PolarHBondContact O-N 3.06Å; D366-R435 IonicContact OD1-CZ 3.62Å; D366-R435 IonicContact OD1-NE 3.31Å; D366-R435 PolarHBondContact OD1-NE 3.16Å; D366-R435 IonicContact OD1-NH2 2.96Å; D366-R435 PolarHBondContact OD1-NH2 2.92Å
367	T	98.5	Very high	97.3	Very high	10 Å²	10	37.8 Å²	37.8	6%	0.061	21%	0.207	C	C	.	.	B	Isolated β-bridge	trans	-95.2	171.2	171.6	75.8	0	0	0	0	112.1	L364 H365 Y369 V370 M433	L364-T367 WeakPolarHBondContact O-CB 3.42Å; L364-T367 WeakPolarHBondContact O-CG2 3.39Å; L364-T367 PolarHBondContact O-N 2.86Å; L364-T367 VanDerWaalsContact O-N 3.13Å; L364-T367 PolarHBondContact O-OG1 3.13Å; H365-T367 PolarHBondContact O-N 3.35Å; T367-Y369 PolarHBondContact O-N 3.35Å; T367-Y369 VanDerWaalsContact O-N 3.12Å; T367-Y369 WeakPolarHBondContact OG1-CB 3.34Å; T367-Y369 PolarHBondContact OG1-N 2.9Å; T367-Y369 VanDerWaalsContact OG1-N 3.13Å; T367-V370 PolarHBondContact O-N 3.12Å; T367-M433 CarbonylContact C-O 3.38Å; T367-M433 VanDerWaalsContact CA-O 3.27Å; T367-M433 WeakPolarHBondContact CA-O 3.24Å; T367-M433 WeakPolarHBondContact CB-O 3.42Å
368	Y	98.4	Very high	96.7	Very high	12 Å²	12	36.4 Å²	36.4	5%	0.047	20%	0.199	C	C	.	.	H	α-helix	trans	-61.6	-11.8	170.1	-91.2	-103.2	0	0	0	114.2	L38 V371 A372 Q425 L428 M433 P434	L38-Y368 WeakPolarHBondContact CD1-OH 3.49Å; Y368-V371 HydrophobicContact CD1-CB 4.49Å; Y368-V371 PolarHBondContact O-N 3.12Å; Y368-A372 WeakPolarHBondContact O-CB 3.01Å; Y368-A372 PolarHBondContact O-N 3.19Å; Y368-Q425 CarbonylContact C-O 3.47Å; Y368-Q425 HydrophobicContact CD1-CB 4.06Å; Y368-Q425 HydrophobicContact CD1-CG 3.85Å; Y368-Q425 HydrophobicContact CE1-CG 4.45Å; Y368-L428 HydrophobicContact CD1-CD1 4.36Å; Y368-L428 HydrophobicContact CG-CB 4.33Å; Y368-M433 HydrophobicContact CD2-CB 4.21Å; Y368-M433 HydrophobicContact CD2-CE 4.11Å; Y368-M433 HydrophobicContact CD2-CG 3.76Å; Y368-M433 HydrophobicContact CD2-SD 3.68Å; Y368-M433 HydrophobicContact CE2-CE 3.5Å; Y368-M433 HydrophobicContact CE2-CG 4.04Å; Y368-M433 HydrophobicContact CE2-SD 3.74Å; Y368-M433 HydrophobicContact CG-SD 4.14Å; Y368-M433 PolarHBondContact N-O 3.02Å; Y368-P434 WeakPolarHBondContact CD2-O 3.23Å; Y368-P434 VanDerWaalsContact CE2-O 3.23Å; Y368-P434 WeakPolarHBondContact CE2-O 3.17Å
369	Y	98.7	Very high	95.7	Very high	19 Å²	19	37 Å²	37	8%	0.075	20%	0.203	C	C	.	.	H	α-helix	trans	-66.7	-43.3	175.7	-165.5	-86.2	0	0	0	110.9	V354 L355 L364 T367 V371 A372 H373 H426 G429 L430	V354-Y369 HydrophobicContact CB-CE1 4.47Å; V354-Y369 HydrophobicContact CG1-CE1 4.39Å; L355-Y369 HydrophobicContact CD1-CD1 4.05Å; L355-Y369 HydrophobicContact CD1-CE1 4.3Å; L355-Y369 HydrophobicContact CD2-CD1 3.76Å; L355-Y369 HydrophobicContact CD2-CE1 4.18Å; L355-Y369 HydrophobicContact CG-CD1 3.89Å; L355-Y369 HydrophobicContact CG-CE1 3.93Å; L364-Y369 HydrophobicContact CD1-CD1 4Å; L364-Y369 HydrophobicContact CD1-CE1 4.09Å; L364-Y369 HydrophobicContact CD1-CG 4.36Å; L364-Y369 HydrophobicContact CD2-CD2 4.35Å; L364-Y369 HydrophobicContact CD2-CG 4.11Å; T367-Y369 PolarHBondContact O-N 3.35Å; T367-Y369 VanDerWaalsContact O-N 3.12Å; T367-Y369 WeakPolarHBondContact OG1-CB 3.34Å; T367-Y369 PolarHBondContact OG1-N 2.9Å; T367-Y369 VanDerWaalsContact OG1-N 3.13Å; Y369-V371 VanDerWaalsContact C-N 3.33Å; Y369-A372 PolarHBondContact O-N 3.29Å; Y369-H373 WeakPolarHBondContact O-CB 3.41Å; Y369-H373 PolarHBondContact O-N 3.5Å; Y369-H426 HydrophobicContact CD2-CB 4.16Å; Y369-H426 AromaticContact CD2-CD2 3.96Å; Y369-H426 HydrophobicContact CE2-CB 4.23Å; Y369-H426 AromaticContact CE2-CD2 3.83Å; Y369-G429 VanDerWaalsContact N-CA 3.34Å; Y369-L430 HydrophobicContact CD2-CD2 4.03Å; Y369-L430 HydrophobicContact CD2-CG 3.83Å; Y369-L430 HydrophobicContact CE2-CD1 4.3Å; Y369-L430 HydrophobicContact CE2-CD2 3.96Å; Y369-L430 HydrophobicContact CE2-CG 3.97Å
370	V	98.3	Very high	95.1	Very high	27 Å²	27	33 Å²	33	16%	0.164	18%	0.175	C	C	.	.	H	α-helix	trans	-65.9	-39.1	175.7	-179.6	0	0	0	0	110.6	L355 L364 T367 F374	L355-V370 HydrophobicContact CD1-CB 4.39Å; L355-V370 HydrophobicContact CD1-CG2 4.03Å; L355-V370 HydrophobicContact CD2-CG2 3.76Å; L364-V370 WeakPolarHBondContact O-CG2 3.36Å; T367-V370 PolarHBondContact O-N 3.12Å; V370-F374 WeakPolarHBondContact O-CB 3.34Å; V370-F374 PolarHBondContact O-N 2.8Å
371	V	98.2	Very high	94.6	Very high	30 Å²	30	29.2 Å²	29.2	18%	0.182	16%	0.156	C	C	.	.	H	α-helix	trans	-61.2	-47.9	175.6	-177.9	0	0	0	0	110.2	Y368 Y369 F374 H375 R435	Y368-V371 HydrophobicContact CD1-CB 4.49Å; Y368-V371 PolarHBondContact O-N 3.12Å; Y369-V371 VanDerWaalsContact C-N 3.33Å; V371-F374 PolarHBondContact O-N 2.76Å; V371-H375 PolarHBondContact O-N 3.18Å; V371-H375 PolarHBondContact O-ND1 2.84Å; V371-R435 HydrophobicContact CG2-CB 3.85Å
372	A	98.3	Very high	94.5	Very high	0 Å²	0	29 Å²	29	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-62	-50.4	178.9	0	0	0	0	0	111.6	Y368 Y369 F374 H375 Y376 Q425 H426	Y368-A372 WeakPolarHBondContact O-CB 3.01Å; Y368-A372 PolarHBondContact O-N 3.19Å; Y369-A372 PolarHBondContact O-N 3.29Å; A372-F374 VanDerWaalsContact C-N 3.33Å; A372-F374 PolarHBondContact O-N 3.49Å; A372-H375 PolarHBondContact O-N 3.45Å; A372-Y376 WeakPolarHBondContact O-CD2 3.43Å; A372-Y376 PolarHBondContact O-N 3.46Å; A372-Q425 HydrophobicContact CB-CB 3.72Å; A372-H426 WeakPolarHBondContact CB-NE2 3.38Å
373	H	98.2	Very high	94.5	Very high	35 Å²	35	25.2 Å²	25.2	16%	0.162	14%	0.136	C	C	.	.	H	α-helix	trans	-51	-53.9	175.2	165.8	61	0	0	0	111.2	G348 T351 G352 L355 Y369 H375 Y376 V377	G348-H373 PolarHBondContact O-CE1 3.2Å; G348-H373 PolarHBondContact O-ND1 2.93Å; T351-H373 PolarHBondContact OG1-ND1 2.9Å; T351-H373 VanDerWaalsContact OG1-ND1 3.12Å; G352-H373 WeakPolarHBondContact CA-CE1 3.38Å; G352-H373 WeakPolarHBondContact CA-ND1 3.31Å; G352-H373 PolarHBondContact N-CE1 3.39Å; G352-H373 PolarHBondContact N-ND1 3.43Å; G352-H373 VanDerWaalsContact N-ND1 3.13Å; L355-H373 HydrophobicContact CD1-CB 3.58Å; Y369-H373 WeakPolarHBondContact O-CB 3.41Å; Y369-H373 PolarHBondContact O-N 3.5Å; H373-H375 VanDerWaalsContact C-N 3.34Å; H373-H375 PolarHBondContact O-N 3.41Å; H373-Y376 PolarHBondContact O-N 3.13Å; H373-Y376 VanDerWaalsContact O-N 3.14Å; H373-V377 PolarHBondContact O-N 3.36Å
374	F	95.9	Very high	94.5	Very high	49 Å²	49	20.3 Å²	20.3	22%	0.215	11%	0.106	C	C	.	.	H	α-helix	trans	-63.5	-38.7	-177.5	-174.6	-115.4	0	0	0	112	V240 V370 V371 A372 V377 L378	V240-F374 HydrophobicContact CB-CE2 4.39Å; V240-F374 HydrophobicContact CG1-CE2 3.61Å; V240-F374 HydrophobicContact CG1-CZ 4.23Å; V370-F374 WeakPolarHBondContact O-CB 3.34Å; V370-F374 PolarHBondContact O-N 2.8Å; V371-F374 PolarHBondContact O-N 2.76Å; A372-F374 VanDerWaalsContact C-N 3.33Å; A372-F374 PolarHBondContact O-N 3.49Å; F374-V377 HydrophobicContact CD2-CG2 4.25Å; F374-V377 WeakPolarHBondContact O-CG2 3.38Å; F374-V377 PolarHBondContact O-N 3.3Å; F374-L378 HydrophobicContact CD1-CB 4.42Å; F374-L378 HydrophobicContact CD2-CB 4.42Å; F374-L378 HydrophobicContact CE1-CB 4.14Å; F374-L378 HydrophobicContact CE1-CD1 4.48Å; F374-L378 HydrophobicContact CE1-CD2 3.73Å; F374-L378 HydrophobicContact CE1-CG 4.32Å; F374-L378 HydrophobicContact CE2-CB 4.11Å; F374-L378 HydrophobicContact CE2-CD1 4.22Å; F374-L378 HydrophobicContact CZ-CB 3.99Å; F374-L378 HydrophobicContact CZ-CD1 3.8Å; F374-L378 HydrophobicContact CZ-CD2 3.89Å; F374-L378 HydrophobicContact CZ-CG 4.08Å; F374-L378 WeakPolarHBondContact O-CA 3.41Å; F374-L378 WeakPolarHBondContact O-CB 3.37Å; F374-L378 PolarHBondContact O-N 2.96Å
375	H	97.9	Very high	94.6	Very high	38 Å²	38	19.8 Å²	19.8	18%	0.176	10%	0.103	C	C	.	.	H	α-helix	trans	-71	-28.5	175.9	-73.8	82.3	0	0	0	112.9	V371 A372 H373 S379 M380 F422	V371-H375 PolarHBondContact O-N 3.18Å; V371-H375 PolarHBondContact O-ND1 2.84Å; A372-H375 PolarHBondContact O-N 3.45Å; H373-H375 VanDerWaalsContact C-N 3.34Å; H373-H375 PolarHBondContact O-N 3.41Å; H375-S379 VanDerWaalsContact O-CA 3.27Å; H375-S379 WeakPolarHBondContact O-CA 3.39Å; H375-S379 WeakPolarHBondContact O-CB 3.45Å; H375-S379 PolarHBondContact O-N 2.97Å; H375-M380 PolarHBondContact O-N 2.82Å; H375-F422 HydrophobicContact CB-CB 4.44Å; H375-F422 HydrophobicContact CB-CD1 3.42Å; H375-F422 VanDerWaalsContact CB-CD1 3.42Å; H375-F422 HydrophobicContact CB-CD2 4.03Å; H375-F422 HydrophobicContact CB-CE1 3.52Å; H375-F422 HydrophobicContact CB-CE2 4.1Å; H375-F422 HydrophobicContact CB-CG 3.7Å; H375-F422 HydrophobicContact CB-CZ 3.86Å; H375-F422 AromaticContact CD2-CE1 3.19Å; H375-F422 WeakPolarHBondContact CD2-CE1 3.44Å; H375-F422 AromaticContact CD2-CZ 3.34Å; H375-F422 WeakPolarHBondContact CD2-CZ 3.49Å; H375-F422 AromaticContact CG-CD1 3.67Å; H375-F422 AromaticContact CG-CE1 3.32Å; H375-F422 AromaticContact CG-CZ 3.79Å; H375-F422 AromaticContact NE2-CE1 3.91Å
376	Y	97.4	Very high	94.6	Very high	0 Å²	0	18.3 Å²	18.3	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-67.5	-39.6	169.5	-91.9	-95.2	0	0	0	113	L344 V347 A372 H373 M380 G381 N419 F422 F423 H426	L344-Y376 HydrophobicContact CB-CD1 4.26Å; L344-Y376 HydrophobicContact CB-CE1 4.43Å; L344-Y376 HydrophobicContact CD2-CD1 4.43Å; L344-Y376 HydrophobicContact CD2-CE1 3.77Å; L344-Y376 WeakPolarHBondContact O-CD1 3.33Å; V347-Y376 HydrophobicContact CB-CD1 4.17Å; V347-Y376 HydrophobicContact CB-CE1 4.26Å; V347-Y376 HydrophobicContact CG1-CD1 4.02Å; V347-Y376 HydrophobicContact CG1-CE1 3.9Å; A372-Y376 WeakPolarHBondContact O-CD2 3.43Å; A372-Y376 PolarHBondContact O-N 3.46Å; H373-Y376 PolarHBondContact O-N 3.13Å; H373-Y376 VanDerWaalsContact O-N 3.14Å; Y376-M380 HydrophobicContact CD1-CE 3.51Å; Y376-M380 HydrophobicContact CD1-SD 3.4Å; Y376-M380 WeakPolarHBondContact CD1-SD 3.49Å; Y376-M380 HydrophobicContact CD2-CE 3.26Å; Y376-M380 HydrophobicContact CD2-SD 4.29Å; Y376-M380 HydrophobicContact CE1-CE 3.61Å; Y376-M380 HydrophobicContact CE1-SD 3.36Å; Y376-M380 WeakPolarHBondContact CE1-SD 3.36Å; Y376-M380 HydrophobicContact CE2-CE 3.35Å; Y376-M380 HydrophobicContact CE2-SD 4.25Å; Y376-M380 HydrophobicContact CG-CE 3.33Å; Y376-M380 HydrophobicContact CG-SD 3.88Å; Y376-M380 CarbonylContact O-C 3.48Å; Y376-M380 VanDerWaalsContact O-CB 3.29Å; Y376-M380 WeakPolarHBondContact O-CB 3.47Å; Y376-G381 PolarHBondContact O-N 3.11Å; Y376-N419 PolarHBondContact OH-OD1 2.98Å; Y376-F422 HydrophobicContact CD2-CB 4.03Å; Y376-F422 HydrophobicContact CE2-CB 3.71Å; Y376-F423 WeakPolarHBondContact OH-CB 3.42Å; Y376-F423 WeakPolarHBondContact OH-CD2 3.45Å; Y376-H426 AromaticContact CD2-CE1 3.58Å; Y376-H426 AromaticContact CE2-CE1 3.58Å
377	V	93.7	Very high	94.6	Very high	27 Å²	27	16.3 Å²	16.3	16%	0.164	9%	0.085	C	C	.	.	H	α-helix	trans	-84.5	-30.8	178.8	-60.6	0	0	0	0	113.2	F345 H373 F374 G381	F345-V377 HydrophobicContact CD2-CB 4.41Å; F345-V377 HydrophobicContact CD2-CG1 4.43Å; F345-V377 HydrophobicContact CE2-CB 4.16Å; F345-V377 HydrophobicContact CE2-CG1 4.24Å; H373-V377 PolarHBondContact O-N 3.36Å; F374-V377 HydrophobicContact CD2-CG2 4.25Å; F374-V377 WeakPolarHBondContact O-CG2 3.38Å; F374-V377 PolarHBondContact O-N 3.3Å; V377-G381 VanDerWaalsContact O-CA 3.24Å; V377-G381 WeakPolarHBondContact O-CA 3.39Å; V377-G381 PolarHBondContact O-N 3.21Å
378	L	85	Confident	94.6	Very high	19 Å²	19	15.8 Å²	15.8	10%	0.099	8%	0.082	C	C	.	.	I	π-helix	trans	-90.5	-65.3	177.8	-169.4	93.1	0	0	0	111.6	L243 F374 G381 A382 V383	L243-L378 HydrophobicContact CB-CD1 4.03Å; L243-L378 HydrophobicContact CD1-CD1 3.46Å; L243-L378 VanDerWaalsContact CD1-CD1 3.46Å; L243-L378 HydrophobicContact CG-CD1 4.31Å; F374-L378 HydrophobicContact CD1-CB 4.42Å; F374-L378 HydrophobicContact CD2-CB 4.42Å; F374-L378 HydrophobicContact CE1-CB 4.14Å; F374-L378 HydrophobicContact CE1-CD1 4.48Å; F374-L378 HydrophobicContact CE1-CD2 3.73Å; F374-L378 HydrophobicContact CE1-CG 4.32Å; F374-L378 HydrophobicContact CE2-CB 4.11Å; F374-L378 HydrophobicContact CE2-CD1 4.22Å; F374-L378 HydrophobicContact CZ-CB 3.99Å; F374-L378 HydrophobicContact CZ-CD1 3.8Å; F374-L378 HydrophobicContact CZ-CD2 3.89Å; F374-L378 HydrophobicContact CZ-CG 4.08Å; F374-L378 WeakPolarHBondContact O-CA 3.41Å; F374-L378 WeakPolarHBondContact O-CB 3.37Å; F374-L378 PolarHBondContact O-N 2.96Å; L378-G381 PolarHBondContact O-N 2.88Å; L378-A382 WeakPolarHBondContact O-CA 3.45Å; L378-A382 WeakPolarHBondContact O-CB 3.16Å; L378-A382 PolarHBondContact O-N 3.25Å; L378-V383 PolarHBondContact O-N 3.43Å
379	S	76.8	Confident	94.6	Very high	23 Å²	23	15.2 Å²	15.2	16%	0.161	8%	0.08	C	C	.	.	I	π-helix	trans	-62.3	-53.2	-177.9	-171.8	0	0	0	0	110.7	H375 G381 V383	H375-S379 VanDerWaalsContact O-CA 3.27Å; H375-S379 WeakPolarHBondContact O-CA 3.39Å; H375-S379 WeakPolarHBondContact O-CB 3.45Å; H375-S379 PolarHBondContact O-N 2.97Å; S379-G381 VanDerWaalsContact C-N 3.33Å; S379-G381 PolarHBondContact O-N 3.12Å; S379-V383 WeakPolarHBondContact O-CB 3.39Å; S379-V383 PolarHBondContact O-N 3.1Å
380	M	82.5	Confident	94.6	Very high	0 Å²	0	16.2 Å²	16.2	0%	0	8%	0.084	C	C	.	.	I	π-helix	trans	-81.2	-10.3	-179.8	-65.4	167.4	-108.4	0	0	114.3	L344 H375 Y376 F384 V418 F422	L344-M380 HydrophobicContact CB-CB 3.67Å; L344-M380 HydrophobicContact CB-CG 4.19Å; L344-M380 HydrophobicContact CB-SD 3.83Å; L344-M380 HydrophobicContact CD1-CB 3.98Å; L344-M380 HydrophobicContact CD1-CG 3.78Å; L344-M380 HydrophobicContact CD1-SD 3.65Å; L344-M380 HydrophobicContact CD2-SD 3.88Å; L344-M380 HydrophobicContact CG-CB 4.43Å; L344-M380 HydrophobicContact CG-SD 3.97Å; H375-M380 PolarHBondContact O-N 2.82Å; Y376-M380 HydrophobicContact CD1-CE 3.51Å; Y376-M380 HydrophobicContact CD1-SD 3.4Å; Y376-M380 WeakPolarHBondContact CD1-SD 3.49Å; Y376-M380 HydrophobicContact CD2-CE 3.26Å; Y376-M380 HydrophobicContact CD2-SD 4.29Å; Y376-M380 HydrophobicContact CE1-CE 3.61Å; Y376-M380 HydrophobicContact CE1-SD 3.36Å; Y376-M380 WeakPolarHBondContact CE1-SD 3.36Å; Y376-M380 HydrophobicContact CE2-CE 3.35Å; Y376-M380 HydrophobicContact CE2-SD 4.25Å; Y376-M380 HydrophobicContact CG-CE 3.33Å; Y376-M380 HydrophobicContact CG-SD 3.88Å; Y376-M380 CarbonylContact O-C 3.48Å; Y376-M380 VanDerWaalsContact O-CB 3.29Å; Y376-M380 WeakPolarHBondContact O-CB 3.47Å; M380-F384 HydrophobicContact CB-CD2 4.36Å; M380-F384 HydrophobicContact CB-CE2 4.44Å; M380-F384 HydrophobicContact CG-CD2 4.47Å; M380-F384 HydrophobicContact CG-CE2 4.09Å; M380-F384 VanDerWaalsContact O-CB 3.28Å; M380-F384 WeakPolarHBondContact O-CB 3.41Å; M380-F384 WeakPolarHBondContact O-CG 3.29Å; M380-V418 HydrophobicContact CG-CB 4.26Å; M380-V418 HydrophobicContact CG-CG2 3.74Å; M380-V418 HydrophobicContact SD-CB 4.47Å; M380-V418 HydrophobicContact SD-CG2 3.89Å; M380-F422 HydrophobicContact CE-CB 3.78Å; M380-F422 HydrophobicContact CE-CD2 3.53Å; M380-F422 HydrophobicContact CE-CG 4.03Å
381	G	87.5	Confident	94.5	Very high	0 Å²	0	15.3 Å²	15.3	0%	0	8%	0.079	C	C	.	.	I	π-helix	trans	-90.8	-74.3	169	0	0	0	0	0	111.8	F341 Y376 V377 L378 S379 A385	F341-G381 WeakPolarHBondContact CD2-O 3.47Å; F341-G381 VanDerWaalsContact CE2-CA 3.48Å; F341-G381 VanDerWaalsContact CE2-O 3.25Å; F341-G381 WeakPolarHBondContact CE2-O 3.5Å; Y376-G381 PolarHBondContact O-N 3.11Å; V377-G381 VanDerWaalsContact O-CA 3.24Å; V377-G381 WeakPolarHBondContact O-CA 3.39Å; V377-G381 PolarHBondContact O-N 3.21Å; L378-G381 PolarHBondContact O-N 2.88Å; S379-G381 VanDerWaalsContact C-N 3.33Å; S379-G381 PolarHBondContact O-N 3.12Å; G381-A385 WeakPolarHBondContact O-CB 3.42Å; G381-A385 PolarHBondContact O-N 3.1Å
382	A	93.3	Very high	94.5	Very high	0 Å²	0	14.2 Å²	14.2	0%	0	7%	0.072	C	C	.	.	I	π-helix	trans	-57.8	-51.7	-176.9	0	0	0	0	0	113.1	V67 M71 L378 F384 A385 I386	V67-A382 HydrophobicContact CG1-CB 3.85Å; V67-A382 HydrophobicContact CG2-CB 4.5Å; M71-A382 HydrophobicContact CE-CB 3.33Å; L378-A382 WeakPolarHBondContact O-CA 3.45Å; L378-A382 WeakPolarHBondContact O-CB 3.16Å; L378-A382 PolarHBondContact O-N 3.25Å; A382-F384 PolarHBondContact O-N 2.89Å; A382-A385 PolarHBondContact O-N 3.28Å; A382-I386 WeakPolarHBondContact O-CB 3.25Å; A382-I386 VanDerWaalsContact O-CG1 3.28Å; A382-I386 WeakPolarHBondContact O-CG1 3.31Å; A382-I386 PolarHBondContact O-N 2.93Å
383	V	95.6	Very high	94.4	Very high	16 Å²	16	14.2 Å²	14.2	10%	0.097	7%	0.072	C	C	.	.	I	π-helix	trans	-69.4	-38.5	-175.1	-174.1	0	0	0	0	111	M66 L378 S379 A385 I386 M387	M66-V383 HydrophobicContact CE-CG1 4.41Å; M66-V383 HydrophobicContact CE-CG2 4.31Å; L378-V383 PolarHBondContact O-N 3.43Å; S379-V383 WeakPolarHBondContact O-CB 3.39Å; S379-V383 PolarHBondContact O-N 3.1Å; V383-A385 PolarHBondContact O-N 2.7Å; V383-I386 WeakPolarHBondContact O-CB 3.42Å; V383-I386 PolarHBondContact O-N 2.84Å; V383-M387 HydrophobicContact CG1-CE 3.93Å; V383-M387 HydrophobicContact CG1-CG 4.21Å; V383-M387 VanDerWaalsContact O-CG 3.25Å; V383-M387 WeakPolarHBondContact O-CG 3.45Å; V383-M387 PolarHBondContact O-N 3.27Å
384	F	98	Very high	94.4	Very high	2 Å²	2	12.9 Å²	12.9	1%	0.009	7%	0.065	C	C	.	.	H	α-helix	trans	-65.7	-39.6	176.5	-85.6	-125.9	0	0	0	112.1	W337 F341 L344 M380 A382 M387 G388 F411 M414 F415 V418	W337-F384 HydrophobicContact CE3-CB 4.1Å; W337-F384 AromaticContact CE3-CD1 3.58Å; W337-F384 HydrophobicContact CE3-CD1 3.58Å; W337-F384 HydrophobicContact CE3-CD2 4.24Å; W337-F384 AromaticContact CE3-CE1 3.95Å; W337-F384 HydrophobicContact CE3-CE1 3.95Å; W337-F384 AromaticContact CE3-CG 3.73Å; W337-F384 HydrophobicContact CE3-CG 3.73Å; W337-F384 HydrophobicContact CE3-CZ 4.43Å; W337-F384 HydrophobicContact CZ3-CB 4.49Å; W337-F384 AromaticContact CZ3-CD1 3.88Å; W337-F384 HydrophobicContact CZ3-CD1 3.88Å; W337-F384 AromaticContact CZ3-CD2 3.84Å; W337-F384 HydrophobicContact CZ3-CD2 3.84Å; W337-F384 AromaticContact CZ3-CE1 3.93Å; W337-F384 HydrophobicContact CZ3-CE1 3.93Å; W337-F384 AromaticContact CZ3-CE2 3.89Å; W337-F384 HydrophobicContact CZ3-CE2 3.89Å; W337-F384 AromaticContact CZ3-CG 3.83Å; W337-F384 HydrophobicContact CZ3-CG 3.83Å; W337-F384 AromaticContact CZ3-CZ 3.94Å; W337-F384 HydrophobicContact CZ3-CZ 3.94Å; F341-F384 HydrophobicContact CB-CB 4.16Å; F341-F384 HydrophobicContact CD2-CB 4.41Å; L344-F384 HydrophobicContact CD1-CD1 4.37Å; L344-F384 HydrophobicContact CD1-CE1 3.69Å; L344-F384 HydrophobicContact CD1-CZ 3.78Å; M380-F384 HydrophobicContact CB-CD2 4.36Å; M380-F384 HydrophobicContact CB-CE2 4.44Å; M380-F384 HydrophobicContact CG-CD2 4.47Å; M380-F384 HydrophobicContact CG-CE2 4.09Å; M380-F384 VanDerWaalsContact O-CB 3.28Å; M380-F384 WeakPolarHBondContact O-CB 3.41Å; M380-F384 WeakPolarHBondContact O-CG 3.29Å; A382-F384 PolarHBondContact O-N 2.89Å; F384-M387 PolarHBondContact O-N 3.41Å; F384-G388 PolarHBondContact O-N 3.29Å; F384-F411 HydrophobicContact CE1-CE2 4.11Å; F384-M414 HydrophobicContact CE2-CG 4.14Å; F384-M414 HydrophobicContact CZ-CG 4.36Å; F384-F415 HydrophobicContact CE1-CD2 4.05Å; F384-F415 HydrophobicContact CZ-CD2 4.39Å; F384-V418 HydrophobicContact CE2-CG2 4Å; F384-V418 HydrophobicContact CZ-CG2 3.93Å
385	A	98.3	Very high	94.4	Very high	0 Å²	0	11.6 Å²	11.6	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-65.2	-40.1	174	0	0	0	0	0	111.6	G247 M250 I251 F341 G381 A382 V383 G389	G247-A385 VanDerWaalsContact CA-CB 3.46Å; M250-A385 HydrophobicContact CE-CB 3.94Å; I251-A385 HydrophobicContact CD1-CB 4.22Å; I251-A385 HydrophobicContact CG1-CB 4.12Å; F341-A385 HydrophobicContact CD2-CB 4.14Å; F341-A385 HydrophobicContact CE2-CB 4.18Å; G381-A385 WeakPolarHBondContact O-CB 3.42Å; G381-A385 PolarHBondContact O-N 3.1Å; A382-A385 PolarHBondContact O-N 3.28Å; V383-A385 PolarHBondContact O-N 2.7Å; A385-G389 PolarHBondContact O-N 3.2Å
386	I	98.4	Very high	94.3	Very high	6 Å²	6	9.8 Å²	9.8	3%	0.031	5%	0.054	C	C	.	.	H	α-helix	trans	-58.7	-47.7	171.6	-73.4	167.3	0	0	0	110.9	I70 M71 F75 A382 V383 G389 F390	I70-I386 HydrophobicContact CB-CD1 4.15Å; I70-I386 HydrophobicContact CG2-CB 4.38Å; I70-I386 HydrophobicContact CG2-CD1 3.91Å; I70-I386 HydrophobicContact CG2-CG1 3.82Å; I70-I386 HydrophobicContact CG2-CG2 3.69Å; M71-I386 HydrophobicContact CE-CD1 4.07Å; M71-I386 HydrophobicContact CE-CG1 4.25Å; M71-I386 HydrophobicContact CG-CD1 3.96Å; M71-I386 HydrophobicContact CG-CG1 3.63Å; M71-I386 HydrophobicContact SD-CG1 4.26Å; F75-I386 HydrophobicContact CE2-CG2 4.44Å; A382-I386 WeakPolarHBondContact O-CB 3.25Å; A382-I386 VanDerWaalsContact O-CG1 3.28Å; A382-I386 WeakPolarHBondContact O-CG1 3.31Å; A382-I386 PolarHBondContact O-N 2.93Å; V383-I386 WeakPolarHBondContact O-CB 3.42Å; V383-I386 PolarHBondContact O-N 2.84Å; I386-G389 PolarHBondContact O-N 3.48Å; I386-F390 WeakPolarHBondContact O-CB 3.46Å; I386-F390 PolarHBondContact O-N 3.05Å
387	M	98.3	Very high	94.2	Very high	29 Å²	29	11.2 Å²	11.2	14%	0.143	6%	0.06	C	C	.	.	H	α-helix	trans	-68.7	-41.7	-177.9	-66.6	-58.7	153.7	0	0	112	W337 V383 F384 F390 I391 M465	W337-M387 HydrophobicContact CD2-CB 3.69Å; W337-M387 HydrophobicContact CE3-CB 3.61Å; W337-M387 HydrophobicContact CE3-CG 4.35Å; W337-M387 HydrophobicContact CG-CB 4.39Å; W337-M387 HydrophobicContact CH2-CB 3.87Å; W337-M387 HydrophobicContact CH2-CG 3.91Å; W337-M387 HydrophobicContact CZ2-CB 3.98Å; W337-M387 HydrophobicContact CZ2-CG 4.35Å; W337-M387 HydrophobicContact CZ3-CB 3.7Å; W337-M387 HydrophobicContact CZ3-CG 3.92Å; V383-M387 HydrophobicContact CG1-CE 3.93Å; V383-M387 HydrophobicContact CG1-CG 4.21Å; V383-M387 VanDerWaalsContact O-CG 3.25Å; V383-M387 WeakPolarHBondContact O-CG 3.45Å; V383-M387 PolarHBondContact O-N 3.27Å; F384-M387 PolarHBondContact O-N 3.41Å; M387-F390 PolarHBondContact O-N 3.4Å; M387-I391 WeakPolarHBondContact O-CB 3.27Å; M387-I391 WeakPolarHBondContact O-CG1 3.34Å; M387-I391 PolarHBondContact O-N 2.92Å; M387-M465 HydrophobicContact SD-CE 3.21Å; M387-M465 WeakPolarHBondContact SD-CE 3.2Å
388	G	98.2	Very high	94.4	Very high	0 Å²	0	11 Å²	11	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-61.4	-46.7	173.4	0	0	0	0	0	111.8	F384 I391 H392	F384-G388 PolarHBondContact O-N 3.29Å; G388-I391 PolarHBondContact O-N 2.94Å; G388-H392 VanDerWaalsContact O-CB 3.29Å; G388-H392 WeakPolarHBondContact O-CB 3.42Å; G388-H392 PolarHBondContact O-N 3.49Å
389	G	98	Very high	94.8	Very high	0 Å²	0	10.3 Å²	10.3	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-63.2	-43.3	175.8	0	0	0	0	0	112.1	A385 I386 H392 W393	A385-G389 PolarHBondContact O-N 3.2Å; I386-G389 PolarHBondContact O-N 3.48Å; G389-H392 PolarHBondContact O-N 3.32Å; G389-W393 PolarHBondContact O-N 3.33Å
390	F	98.3	Very high	95.8	Very high	39 Å²	39	11.7 Å²	11.7	17%	0.171	6%	0.059	C	C	.	.	H	α-helix	trans	-61.3	-50.1	177.8	-179.5	-99.7	0	0	0	110.2	F75 I386 M387 H392 W393 F394 L402 M465 I469	F75-F390 HydrophobicContact CZ-CB 4.27Å; I386-F390 WeakPolarHBondContact O-CB 3.46Å; I386-F390 PolarHBondContact O-N 3.05Å; M387-F390 PolarHBondContact O-N 3.4Å; F390-H392 VanDerWaalsContact C-N 3.29Å; F390-H392 PolarHBondContact O-N 3.25Å; F390-W393 PolarHBondContact O-N 3.45Å; F390-F394 AromaticContact CE1-CD2 3.73Å; F390-F394 HydrophobicContact CE1-CD2 3.73Å; F390-F394 HydrophobicContact CE1-CE2 4.27Å; F390-F394 HydrophobicContact CE1-CG 4.44Å; F390-F394 AromaticContact CE2-CD2 3.8Å; F390-F394 HydrophobicContact CE2-CD2 3.8Å; F390-F394 HydrophobicContact CE2-CE2 4.39Å; F390-F394 AromaticContact CZ-CD2 3.3Å; F390-F394 HydrophobicContact CZ-CD2 3.3Å; F390-F394 AromaticContact CZ-CE2 3.68Å; F390-F394 HydrophobicContact CZ-CE2 3.68Å; F390-F394 HydrophobicContact CZ-CG 4.36Å; F390-F394 VanDerWaalsContact O-CA 3.31Å; F390-F394 WeakPolarHBondContact O-CA 3.41Å; F390-F394 WeakPolarHBondContact O-CB 3.35Å; F390-F394 PolarHBondContact O-N 3.31Å; F390-L402 HydrophobicContact CD1-CD1 4.49Å; F390-L402 HydrophobicContact CE1-CD1 4.27Å; F390-M465 HydrophobicContact CD1-CE 3.92Å; F390-M465 HydrophobicContact CD1-SD 4.18Å; F390-M465 HydrophobicContact CE1-CE 4.23Å; F390-M465 HydrophobicContact CE1-SD 3.87Å; F390-I469 HydrophobicContact CE1-CD1 4.09Å; F390-I469 HydrophobicContact CE1-CG1 4.03Å; F390-I469 HydrophobicContact CZ-CD1 3.7Å; F390-I469 HydrophobicContact CZ-CG1 3.85Å
391	I	97.8	Very high	96.4	Very high	9 Å²	9	13.8 Å²	13.8	5%	0.046	7%	0.072	C	C	.	.	H	α-helix	trans	-63.1	-37.5	179.1	-70.2	163.7	0	0	0	111.7	A333 A334 W337 M387 G388 L402	A333-I391 HydrophobicContact CB-CD1 4.4Å; A333-I391 HydrophobicContact CB-CG2 4.13Å; A334-I391 HydrophobicContact CB-CG2 4.16Å; W337-I391 HydrophobicContact CG-CD1 4.45Å; M387-I391 WeakPolarHBondContact O-CB 3.27Å; M387-I391 WeakPolarHBondContact O-CG1 3.34Å; M387-I391 PolarHBondContact O-N 2.92Å; G388-I391 PolarHBondContact O-N 2.94Å; I391-L402 HydrophobicContact CB-CD1 4.4Å; I391-L402 HydrophobicContact CG1-CD1 3.88Å
392	H	96.5	Very high	96.8	Very high	7 Å²	7	14.3 Å²	14.3	3%	0.032	8%	0.075	C	C	.	.	H	α-helix	trans	-68.1	-49.2	178.7	178.7	54.6	0	0	0	112.4	I254 Y257 Y258 A334 G388 G389 F390 P395 W491	I254-H392 HydrophobicContact CD1-CB 4.43Å; I254-H392 HydrophobicContact CG1-CB 4.04Å; Y257-H392 AromaticContact CD1-CE1 3.67Å; Y257-H392 AromaticContact CG-CE1 3.65Å; Y258-H392 AromaticContact CE2-ND1 3.7Å; A334-H392 HydrophobicContact CB-CB 4.22Å; G388-H392 VanDerWaalsContact O-CB 3.29Å; G388-H392 WeakPolarHBondContact O-CB 3.42Å; G388-H392 PolarHBondContact O-N 3.49Å; G389-H392 PolarHBondContact O-N 3.32Å; F390-H392 VanDerWaalsContact C-N 3.29Å; F390-H392 PolarHBondContact O-N 3.25Å; H392-P395 WeakPolarHBondContact O-CD 3.35Å; H392-W491 AromaticContact CE1-CZ2 3.88Å; H392-W491 AromaticContact NE2-CZ2 3.88Å; H392-W491 WeakPolarHBondContact O-CH2 3.42Å
393	W	97.4	Very high	97	Very high	0 Å²	0	16.5 Å²	16.5	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-96.3	-1.2	-176	-68.5	-66.6	0	0	0	114.7	F75 L79 M83 M250 H253 G389 F390 P395 L396 F397 W491	F75-W393 AromaticContact CD1-CE3 3.92Å; F75-W393 HydrophobicContact CD1-CE3 3.92Å; F75-W393 HydrophobicContact CD1-CZ3 4.4Å; F75-W393 AromaticContact CE1-CE3 3.71Å; F75-W393 HydrophobicContact CE1-CE3 3.71Å; F75-W393 HydrophobicContact CE1-CZ3 4.4Å; L79-W393 HydrophobicContact CD1-CD2 3.7Å; L79-W393 HydrophobicContact CD1-CE3 3.81Å; L79-W393 HydrophobicContact CD1-CG 4.34Å; L79-W393 HydrophobicContact CD1-CH2 4Å; L79-W393 HydrophobicContact CD1-CZ2 3.86Å; L79-W393 HydrophobicContact CD1-CZ3 3.97Å; L79-W393 HydrophobicContact CD2-CD2 4.25Å; L79-W393 HydrophobicContact CD2-CG 4.08Å; M83-W393 HydrophobicContact CE-CZ2 3.7Å; M250-W393 HydrophobicContact CB-CH2 4.14Å; M250-W393 HydrophobicContact CB-CZ3 3.95Å; M250-W393 HydrophobicContact CG-CH2 4.01Å; M250-W393 HydrophobicContact CG-CZ3 3.66Å; M250-W393 HydrophobicContact SD-CZ3 4.04Å; H253-W393 HydrophobicContact CB-CH2 4.05Å; H253-W393 HydrophobicContact CB-CZ2 3.97Å; G389-W393 PolarHBondContact O-N 3.33Å; F390-W393 PolarHBondContact O-N 3.45Å; W393-P395 VanDerWaalsContact C-N 3.27Å; W393-L396 HydrophobicContact CB-CB 4.4Å; W393-L396 WeakPolarHBondContact O-CA 3.14Å; W393-L396 VanDerWaalsContact O-CB 3.24Å; W393-L396 WeakPolarHBondContact O-CB 3.36Å; W393-L396 PolarHBondContact O-N 3.06Å; W393-F397 HydrophobicContact CB-CD2 4.39Å; W393-F397 HydrophobicContact CB-CE1 3.89Å; W393-F397 HydrophobicContact CB-CE2 3.72Å; W393-F397 HydrophobicContact CB-CZ 3.44Å; W393-F397 VanDerWaalsContact CB-CZ 3.44Å; W393-F397 HydrophobicContact CG-CZ 4.26Å; W393-F397 WeakPolarHBondContact O-CD2 3.22Å; W393-F397 WeakPolarHBondContact O-CG 3.42Å; W393-F397 PolarHBondContact O-N 3.25Å; W393-W491 AromaticContact CD1-CH2 3.95Å; W393-W491 AromaticContact CD1-CZ2 3.42Å; W393-W491 VanDerWaalsContact CD1-CZ2 3.42Å; W393-W491 HydrophobicContact CG-CZ2 4.39Å; W393-W491 AromaticContact NE1-CZ2 3.85Å
394	F	97.3	Very high	96.9	Very high	7 Å²	7	19.4 Å²	19.4	3%	0.031	10%	0.099	C	C	.	.	H	α-helix	trans	-51.9	-41.9	174.7	-178	-97.7	0	0	0	112.9	F390 L396 F397 S398 Y400 L402 A472 F473	F390-F394 AromaticContact CE1-CD2 3.73Å; F390-F394 HydrophobicContact CE1-CD2 3.73Å; F390-F394 HydrophobicContact CE1-CE2 4.27Å; F390-F394 HydrophobicContact CE1-CG 4.44Å; F390-F394 AromaticContact CE2-CD2 3.8Å; F390-F394 HydrophobicContact CE2-CD2 3.8Å; F390-F394 HydrophobicContact CE2-CE2 4.39Å; F390-F394 AromaticContact CZ-CD2 3.3Å; F390-F394 HydrophobicContact CZ-CD2 3.3Å; F390-F394 AromaticContact CZ-CE2 3.68Å; F390-F394 HydrophobicContact CZ-CE2 3.68Å; F390-F394 HydrophobicContact CZ-CG 4.36Å; F390-F394 VanDerWaalsContact O-CA 3.31Å; F390-F394 WeakPolarHBondContact O-CA 3.41Å; F390-F394 WeakPolarHBondContact O-CB 3.35Å; F390-F394 PolarHBondContact O-N 3.31Å; F394-L396 VanDerWaalsContact C-N 3.33Å; F394-L396 PolarHBondContact O-N 2.96Å; F394-F397 PolarHBondContact O-N 3.44Å; F394-S398 WeakPolarHBondContact CE1-OG 3.22Å; F394-S398 WeakPolarHBondContact O-CB 3.47Å; F394-S398 PolarHBondContact O-N 3.17Å; F394-S398 PolarHBondContact O-OG 3.07Å; F394-Y400 VanDerWaalsContact CD1-O 3.26Å; F394-Y400 WeakPolarHBondContact CD1-O 3.03Å; F394-L402 HydrophobicContact CB-CD1 4.17Å; F394-L402 HydrophobicContact CB-CG 4.36Å; F394-L402 HydrophobicContact CD1-CD1 4.25Å; F394-L402 HydrophobicContact CD1-CD2 3.75Å; F394-L402 HydrophobicContact CD1-CG 3.56Å; F394-L402 HydrophobicContact CD2-CD2 4.44Å; F394-L402 HydrophobicContact CE1-CD2 3.59Å; F394-L402 HydrophobicContact CE1-CG 3.92Å; F394-L402 HydrophobicContact CE2-CD2 4.29Å; F394-L402 HydrophobicContact CG-CD1 4.13Å; F394-L402 HydrophobicContact CG-CD2 4.17Å; F394-L402 HydrophobicContact CG-CG 3.94Å; F394-L402 HydrophobicContact CZ-CD2 3.87Å; F394-A472 HydrophobicContact CE1-CB 3.76Å; F394-A472 HydrophobicContact CZ-CB 3.91Å; F394-F473 HydrophobicContact CE2-CE2 4.35Å; F394-F473 HydrophobicContact CZ-CE2 4.11Å; F394-F473 HydrophobicContact CZ-CZ 4.44Å
395	P	95.8	Very high	96.9	Very high	22 Å²	22	23.6 Å²	23.6	14%	0.143	13%	0.125	C	C	.	.	H	α-helix	trans	-65.7	-34.8	175	-16.1	30.7	0	0	0	113	H392 W393 G399 Y400 T401 V479 C495	H392-P395 WeakPolarHBondContact O-CD 3.35Å; W393-P395 VanDerWaalsContact C-N 3.27Å; P395-G399 VanDerWaalsContact O-CA 3.24Å; P395-G399 WeakPolarHBondContact O-CA 3.47Å; P395-G399 PolarHBondContact O-N 3.41Å; P395-Y400 WeakPolarHBondContact CA-O 2.97Å; P395-T401 HydrophobicContact CG-CG2 4.5Å; P395-V479 HydrophobicContact CB-CG2 3.43Å; P395-V479 VanDerWaalsContact CB-CG2 3.43Å; P395-C495 WeakPolarHBondContact O-CB 3.3Å
396	L	95.8	Very high	96.9	Very high	0 Å²	0	28 Å²	28	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-62.7	-43.8	174.9	-175.4	64.1	0	0	0	111.4	L79 L82 W393 F394 E490 W491 P496 P497	L79-L396 HydrophobicContact CD2-CD2 3.72Å; L82-L396 HydrophobicContact CD1-CD2 4.21Å; W393-L396 HydrophobicContact CB-CB 4.4Å; W393-L396 WeakPolarHBondContact O-CA 3.14Å; W393-L396 VanDerWaalsContact O-CB 3.24Å; W393-L396 WeakPolarHBondContact O-CB 3.36Å; W393-L396 PolarHBondContact O-N 3.06Å; F394-L396 VanDerWaalsContact C-N 3.33Å; F394-L396 PolarHBondContact O-N 2.96Å; L396-E490 WeakPolarHBondContact CD1-O 3.39Å; L396-E490 HydrophobicContact CD2-CB 4.11Å; L396-E490 HydrophobicContact CD2-CG 4.13Å; L396-W491 HydrophobicContact CB-CE3 4.2Å; L396-W491 HydrophobicContact CB-CH2 3.76Å; L396-W491 HydrophobicContact CB-CZ3 3.55Å; L396-W491 HydrophobicContact CD1-CE3 4.03Å; L396-W491 HydrophobicContact CD1-CZ3 4.23Å; L396-W491 HydrophobicContact CG-CZ3 4.4Å; L396-P496 WeakPolarHBondContact O-CA 3.49Å; L396-P497 HydrophobicContact CD1-CG 4.4Å; L396-P497 WeakPolarHBondContact O-CD 3.49Å
397	F	96.7	Very high	96.9	Very high	29 Å²	29	27.7 Å²	27.7	13%	0.127	14%	0.141	C	C	.	.	H	α-helix	trans	-75.7	-38.4	-176.1	-54.2	-28.4	0	0	0	112.9	L17 F75 W78 L79 W393 F394	L17-F397 HydrophobicContact CD1-CD2 4.09Å; L17-F397 HydrophobicContact CD1-CE2 4.06Å; F75-F397 HydrophobicContact CD1-CE2 4.15Å; F75-F397 AromaticContact CD1-CZ 3.77Å; F75-F397 HydrophobicContact CD1-CZ 3.77Å; F75-F397 AromaticContact CE1-CE2 3.67Å; F75-F397 HydrophobicContact CE1-CE2 3.67Å; F75-F397 AromaticContact CE1-CZ 3.73Å; F75-F397 HydrophobicContact CE1-CZ 3.73Å; F75-F397 HydrophobicContact CZ-CE2 4.48Å; W78-F397 HydrophobicContact CB-CD1 4.45Å; W78-F397 HydrophobicContact CB-CE1 3.76Å; W78-F397 HydrophobicContact CB-CZ 4.34Å; W78-F397 AromaticContact CD2-CD1 3.59Å; W78-F397 HydrophobicContact CD2-CD1 3.59Å; W78-F397 AromaticContact CD2-CE1 3.82Å; W78-F397 HydrophobicContact CD2-CE1 3.82Å; W78-F397 AromaticContact CE2-CD1 3.93Å; W78-F397 AromaticContact CE3-CD1 3.72Å; W78-F397 HydrophobicContact CE3-CD1 3.72Å; W78-F397 HydrophobicContact CE3-CE1 4.04Å; W78-F397 AromaticContact CG-CD1 3.94Å; W78-F397 HydrophobicContact CG-CD1 3.94Å; W78-F397 AromaticContact CG-CE1 3.71Å; W78-F397 HydrophobicContact CG-CE1 3.71Å; W78-F397 HydrophobicContact CG-CZ 4.42Å; W78-F397 HydrophobicContact CH2-CD1 4.43Å; W78-F397 HydrophobicContact CZ2-CB 4.43Å; W78-F397 HydrophobicContact CZ2-CD1 4.35Å; W78-F397 HydrophobicContact CZ3-CD1 4.14Å; L79-F397 HydrophobicContact CD2-CE1 4.11Å; L79-F397 HydrophobicContact CD2-CZ 4.45Å; W393-F397 HydrophobicContact CB-CD2 4.39Å; W393-F397 HydrophobicContact CB-CE1 3.89Å; W393-F397 HydrophobicContact CB-CE2 3.72Å; W393-F397 HydrophobicContact CB-CZ 3.44Å; W393-F397 VanDerWaalsContact CB-CZ 3.44Å; W393-F397 HydrophobicContact CG-CZ 4.26Å; W393-F397 WeakPolarHBondContact O-CD2 3.22Å; W393-F397 WeakPolarHBondContact O-CG 3.42Å; W393-F397 PolarHBondContact O-N 3.25Å; F394-F397 PolarHBondContact O-N 3.44Å
398	S	96.4	Very high	96.9	Very high	22 Å²	22	30.2 Å²	30.2	15%	0.154	15%	0.151	C	C	.	.	H	α-helix	trans	-109.2	-21.2	-168.9	70.2	0	0	0	0	114.9	F394 Y400	F394-S398 WeakPolarHBondContact CE1-OG 3.22Å; F394-S398 WeakPolarHBondContact O-CB 3.47Å; F394-S398 PolarHBondContact O-N 3.17Å; F394-S398 PolarHBondContact O-OG 3.07Å; S398-Y400 PolarHBondContact O-N 3.4Å; S398-Y400 PolarHBondContact OG-N 2.96Å; S398-Y400 VanDerWaalsContact OG-N 3.08Å; S398-Y400 PolarHBondContact OG-O 3.23Å
399	G	95.3	Very high	96.9	Very high	6 Å²	6	33.9 Å²	33.9	6%	0.062	17%	0.17	C	C	.	.	S	Bend	trans	75.8	1	-167.2	0	0	0	0	0	115.2	P395 V479 C495	P395-G399 VanDerWaalsContact O-CA 3.24Å; P395-G399 WeakPolarHBondContact O-CA 3.47Å; P395-G399 PolarHBondContact O-N 3.41Å; G399-V479 PolarHBondContact O-N 3.12Å; G399-C495 WeakPolarHBondContact CA-O 3.08Å
400	Y	96	Very high	96.9	Very high	51 Å²	51	33.9 Å²	33.9	20%	0.2	17%	0.17	C	C	.	.	B	Isolated β-bridge	trans	-114.7	157.3	-178.9	-57.7	-58	0	0	0	112.7	F394 P395 S398 F473 K476 R477 K478	F394-Y400 VanDerWaalsContact CD1-O 3.26Å; F394-Y400 WeakPolarHBondContact CD1-O 3.03Å; P395-Y400 WeakPolarHBondContact CA-O 2.97Å; S398-Y400 PolarHBondContact O-N 3.4Å; S398-Y400 PolarHBondContact OG-N 2.96Å; S398-Y400 VanDerWaalsContact OG-N 3.08Å; S398-Y400 PolarHBondContact OG-O 3.23Å; Y400-F473 AromaticContact CD2-CD1 3.66Å; Y400-F473 HydrophobicContact CD2-CD1 3.66Å; Y400-F473 AromaticContact CD2-CE1 3.73Å; Y400-F473 HydrophobicContact CD2-CE1 3.73Å; Y400-F473 AromaticContact CE2-CD1 3.64Å; Y400-F473 HydrophobicContact CE2-CD1 3.64Å; Y400-F473 AromaticContact CE2-CE1 3.84Å; Y400-F473 HydrophobicContact CE2-CE1 3.84Å; Y400-K476 HydrophobicContact CD1-CB 4.26Å; Y400-K476 HydrophobicContact CE1-CB 3.68Å; Y400-K476 HydrophobicContact CE1-CG 4.12Å; Y400-R477 CarbonylContact C-O 3.47Å; Y400-R477 WeakPolarHBondContact CA-O 3.37Å; Y400-K478 HydrophobicContact CD1-CG 4.33Å; Y400-K478 HydrophobicContact CE1-CG 4.15Å
401	T	95.4	Very high	97	Very high	45 Å²	45	33.3 Å²	33.3	28%	0.276	17%	0.167	S	C	.	.			trans	-105.2	137.6	177.6	61.2	0	0	0	0	112.2	P395 R477 V479	P395-T401 HydrophobicContact CG-CG2 4.5Å; T401-R477 PolarHBondContact N-O 3.02Å; T401-R477 PolarHBondContact O-NE 2.88Å; T401-R477 PolarHBondContact O-NH2 3.24Å; T401-R477 WeakPolarHBondContact OG1-CB 3.27Å; T401-R477 PolarHBondContact OG1-O 2.75Å; T401-V479 HydrophobicContact CG2-CG2 3.87Å
402	L	96.3	Very high	97	Very high	10 Å²	10	34.9 Å²	34.9	5%	0.052	18%	0.182	C	C	.	.			trans	-73.1	142	168.8	-61.6	174	0	0	0	109.8	F390 I391 F394 Q404 M468 A472	F390-L402 HydrophobicContact CD1-CD1 4.49Å; F390-L402 HydrophobicContact CE1-CD1 4.27Å; I391-L402 HydrophobicContact CB-CD1 4.4Å; I391-L402 HydrophobicContact CG1-CD1 3.88Å; F394-L402 HydrophobicContact CB-CD1 4.17Å; F394-L402 HydrophobicContact CB-CG 4.36Å; F394-L402 HydrophobicContact CD1-CD1 4.25Å; F394-L402 HydrophobicContact CD1-CD2 3.75Å; F394-L402 HydrophobicContact CD1-CG 3.56Å; F394-L402 HydrophobicContact CD2-CD2 4.44Å; F394-L402 HydrophobicContact CE1-CD2 3.59Å; F394-L402 HydrophobicContact CE1-CG 3.92Å; F394-L402 HydrophobicContact CE2-CD2 4.29Å; F394-L402 HydrophobicContact CG-CD1 4.13Å; F394-L402 HydrophobicContact CG-CD2 4.17Å; F394-L402 HydrophobicContact CG-CG 3.94Å; F394-L402 HydrophobicContact CZ-CD2 3.87Å; L402-Q404 PolarHBondContact O-N 3.22Å; L402-M468 HydrophobicContact CB-CE 4.32Å; L402-M468 HydrophobicContact CD1-CE 3.99Å; L402-M468 HydrophobicContact CD2-CB 4.45Å; L402-M468 HydrophobicContact CD2-CE 4.4Å; L402-M468 HydrophobicContact CG-CE 4.47Å; L402-A472 HydrophobicContact CD2-CB 3.94Å
403	D	96.7	Very high	97.1	Very high	46 Å²	46	36.8 Å²	36.8	25%	0.246	19%	0.191	C	C	.	.			trans	-63	125.3	170.4	-177.5	-84.6	0	0	0	110.2	T405 Y406 A407	D403-T405 VanDerWaalsContact C-N 3.3Å; D403-T405 PolarHBondContact O-N 3.38Å; D403-T405 VanDerWaalsContact OD1-CA 3.3Å; D403-T405 WeakPolarHBondContact OD1-CA 3.48Å; D403-T405 WeakPolarHBondContact OD1-CB 3.48Å; D403-T405 PolarHBondContact OD1-N 2.87Å; D403-Y406 HydrophobicContact CB-CD2 3.72Å; D403-Y406 HydrophobicContact CB-CE2 4.45Å; D403-Y406 HydrophobicContact CB-CG 4.45Å; D403-Y406 PolarHBondContact OD1-N 3.03Å; D403-A407 VanDerWaalsContact O-CB 3.32Å; D403-A407 WeakPolarHBondContact O-CB 3.37Å; D403-A407 PolarHBondContact O-N 2.92Å
404	Q	95	Very high	97.1	Very high	78 Å²	78	37.5 Å²	37.5	36%	0.364	20%	0.195	S	C	.	.	H	α-helix	trans	-70.7	-25.8	-175.1	-72.1	-62.4	-52	0	0	113	A333 L402 K408	A333-Q404 VanDerWaalsContact N-OE1 3.15Å; L402-Q404 PolarHBondContact O-N 3.22Å; Q404-K408 WeakPolarHBondContact O-CB 3.28Å; Q404-K408 WeakPolarHBondContact O-CG 3.48Å; Q404-K408 PolarHBondContact O-N 3.06Å; Q404-K408 VanDerWaalsContact O-N 3.08Å
405	T	97.4	Very high	97.2	Very high	89 Å²	89	39.9 Å²	39.9	55%	0.546	21%	0.205	S	C	.	.	H	α-helix	trans	-69.9	-52	177.4	-51.6	0	0	0	0	109.3	D403 A407 K408 I409	D403-T405 VanDerWaalsContact C-N 3.3Å; D403-T405 PolarHBondContact O-N 3.38Å; D403-T405 VanDerWaalsContact OD1-CA 3.3Å; D403-T405 WeakPolarHBondContact OD1-CA 3.48Å; D403-T405 WeakPolarHBondContact OD1-CB 3.48Å; D403-T405 PolarHBondContact OD1-N 2.87Å; T405-A407 VanDerWaalsContact C-N 3.31Å; T405-A407 PolarHBondContact O-N 3.38Å; T405-K408 PolarHBondContact O-N 3.35Å; T405-I409 HydrophobicContact CG2-CD1 4.05Å; T405-I409 WeakPolarHBondContact O-CG1 3.17Å; T405-I409 PolarHBondContact O-N 3.32Å
406	Y	98	Very high	97.3	Very high	92 Å²	92	43.2 Å²	43.2	36%	0.361	22%	0.221	S	C	.	.	H	α-helix	trans	-61.7	-39.5	176.2	-64	-45.9	0	0	0	112	D403 K408 I409 H410 F467	D403-Y406 HydrophobicContact CB-CD2 3.72Å; D403-Y406 HydrophobicContact CB-CE2 4.45Å; D403-Y406 HydrophobicContact CB-CG 4.45Å; D403-Y406 PolarHBondContact OD1-N 3.03Å; Y406-K408 VanDerWaalsContact C-N 3.34Å; Y406-K408 PolarHBondContact O-N 2.72Å; Y406-I409 PolarHBondContact O-N 2.71Å; Y406-H410 VanDerWaalsContact O-CB 3.32Å; Y406-H410 WeakPolarHBondContact O-CB 3.45Å; Y406-H410 PolarHBondContact O-N 3.05Å; Y406-F467 HydrophobicContact CD2-CE1 4.1Å; Y406-F467 HydrophobicContact CE1-CE1 4.42Å; Y406-F467 AromaticContact CE2-CE1 3.94Å; Y406-F467 HydrophobicContact CE2-CE1 3.94Å; Y406-F467 HydrophobicContact CE2-CZ 4.5Å; Y406-F467 HydrophobicContact CG-CE1 4.45Å
407	A	98.1	Very high	97.4	Very high	0 Å²	0	43.2 Å²	43.2	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-63.6	-35.8	177.8	0	0	0	0	0	113.6	A333 D403 T405 F411 M468	A333-A407 HydrophobicContact CB-CB 3.46Å; A333-A407 VanDerWaalsContact CB-CB 3.46Å; D403-A407 VanDerWaalsContact O-CB 3.32Å; D403-A407 WeakPolarHBondContact O-CB 3.37Å; D403-A407 PolarHBondContact O-N 2.92Å; T405-A407 VanDerWaalsContact C-N 3.31Å; T405-A407 PolarHBondContact O-N 3.38Å; A407-F411 PolarHBondContact O-N 3.36Å; A407-F411 VanDerWaalsContact O-N 3.14Å; A407-M468 VanDerWaalsContact CA-CE 3.49Å; A407-M468 HydrophobicContact CB-CE 3.59Å
408	K	98.6	Very high	97.4	Very high	83 Å²	83	42 Å²	42	36%	0.361	22%	0.216	S	C	.	.	H	α-helix	trans	-72.5	-39.5	174.4	-72.4	174.3	179.9	-175.3	0	112.2	W331 A333 L336 Q404 T405 Y406 H410 F411 A412	W331-K408 WeakPolarHBondContact O-CE 3.43Å; W331-K408 PolarHBondContact O-NZ 2.88Å; A333-K408 HydrophobicContact CB-CG 4.17Å; L336-K408 HydrophobicContact CD1-CB 4.32Å; L336-K408 HydrophobicContact CD1-CG 3.86Å; Q404-K408 WeakPolarHBondContact O-CB 3.28Å; Q404-K408 WeakPolarHBondContact O-CG 3.48Å; Q404-K408 PolarHBondContact O-N 3.06Å; Q404-K408 VanDerWaalsContact O-N 3.08Å; T405-K408 PolarHBondContact O-N 3.35Å; Y406-K408 VanDerWaalsContact C-N 3.34Å; Y406-K408 PolarHBondContact O-N 2.72Å; K408-H410 VanDerWaalsContact C-N 3.34Å; K408-F411 WeakPolarHBondContact O-CB 3.27Å; K408-F411 PolarHBondContact O-N 2.92Å; K408-A412 PolarHBondContact O-N 3.11Å
409	I	98.6	Very high	97.5	Very high	76 Å²	76	42.5 Å²	42.5	39%	0.39	22%	0.217	S	C	.	.	H	α-helix	trans	-62.4	-44.8	174	-67.2	167.3	0	0	0	109.9	T405 Y406 F411 A412 I413 L464	T405-I409 HydrophobicContact CG2-CD1 4.05Å; T405-I409 WeakPolarHBondContact O-CG1 3.17Å; T405-I409 PolarHBondContact O-N 3.32Å; Y406-I409 PolarHBondContact O-N 2.71Å; I409-F411 VanDerWaalsContact C-N 3.34Å; I409-F411 PolarHBondContact O-N 3.25Å; I409-A412 PolarHBondContact O-N 2.78Å; I409-A412 VanDerWaalsContact O-N 3.11Å; I409-I413 HydrophobicContact CG2-CD1 3.65Å; I409-I413 HydrophobicContact CG2-CG1 4.19Å; I409-I413 WeakPolarHBondContact O-CG1 3.36Å; I409-I413 PolarHBondContact O-N 2.91Å; I409-L464 HydrophobicContact CB-CD2 4.33Å; I409-L464 HydrophobicContact CG2-CD2 3.8Å
410	H	98.6	Very high	97.6	Very high	1 Å²	1	45.4 Å²	45.4	1%	0.005	23%	0.231	C	C	.	.	H	α-helix	trans	-56.4	-46.6	176.1	175.5	-116.2	0	0	0	112.1	W337 Y406 K408 M414 A461 L464 M465 M468	W337-H410 AromaticContact CH2-CE1 3.87Å; W337-H410 AromaticContact CZ2-CE1 3.44Å; W337-H410 VanDerWaalsContact CZ2-CE1 3.44Å; W337-H410 WeakPolarHBondContact CZ2-CE1 3.25Å; W337-H410 AromaticContact CZ2-ND1 3.4Å; W337-H410 WeakPolarHBondContact CZ2-ND1 3.49Å; Y406-H410 VanDerWaalsContact O-CB 3.32Å; Y406-H410 WeakPolarHBondContact O-CB 3.45Å; Y406-H410 PolarHBondContact O-N 3.05Å; K408-H410 VanDerWaalsContact C-N 3.34Å; H410-M414 WeakPolarHBondContact O-CB 3.24Å; H410-M414 PolarHBondContact O-N 2.94Å; H410-A461 PolarHBondContact CD2-O 3.3Å; H410-A461 PolarHBondContact NE2-O 2.87Å; H410-L464 HydrophobicContact CB-CD2 3.79Å; H410-L464 HydrophobicContact CB-CG 4.17Å; H410-M465 VanDerWaalsContact CE1-CE 3.48Å; H410-M465 WeakPolarHBondContact CE1-CE 3.37Å; H410-M468 HydrophobicContact CB-SD 3.64Å
411	F	98.6	Very high	97.7	Very high	27 Å²	27	43.2 Å²	43.2	12%	0.118	22%	0.223	C	C	.	.	H	α-helix	trans	-56.6	-51.3	172	169.2	-100.2	0	0	0	112.2	L336 W337 F384 A407 K408 I409 I413 M414 F415	L336-F411 HydrophobicContact CB-CD1 3.66Å; L336-F411 HydrophobicContact CB-CD2 4.1Å; L336-F411 HydrophobicContact CB-CE1 3.78Å; L336-F411 HydrophobicContact CB-CE2 4.21Å; L336-F411 HydrophobicContact CB-CG 3.82Å; L336-F411 HydrophobicContact CB-CZ 4.05Å; L336-F411 HydrophobicContact CD1-CD1 3.88Å; L336-F411 HydrophobicContact CD1-CE1 4.38Å; L336-F411 HydrophobicContact CD1-CG 4.47Å; L336-F411 HydrophobicContact CG-CD1 4.35Å; L336-F411 WeakPolarHBondContact O-CE2 3.43Å; L336-F411 WeakPolarHBondContact O-CZ 3.33Å; W337-F411 HydrophobicContact CD2-CB 4.49Å; W337-F411 AromaticContact CD2-CD2 3.71Å; W337-F411 HydrophobicContact CD2-CD2 3.71Å; W337-F411 AromaticContact CE2-CD2 3.86Å; W337-F411 HydrophobicContact CE3-CD2 4.03Å; W337-F411 AromaticContact CG-CD2 3.99Å; W337-F411 HydrophobicContact CG-CD2 3.99Å; W337-F411 VanDerWaalsContact CZ2-CA 3.5Å; W337-F411 HydrophobicContact CZ2-CB 4Å; W337-F411 HydrophobicContact CZ2-CD2 4.31Å; W337-F411 HydrophobicContact CZ3-CD2 4.49Å; F384-F411 HydrophobicContact CE1-CE2 4.11Å; A407-F411 PolarHBondContact O-N 3.36Å; A407-F411 VanDerWaalsContact O-N 3.14Å; K408-F411 WeakPolarHBondContact O-CB 3.27Å; K408-F411 PolarHBondContact O-N 2.92Å; I409-F411 VanDerWaalsContact C-N 3.34Å; I409-F411 PolarHBondContact O-N 3.25Å; F411-I413 PolarHBondContact O-N 3.31Å; F411-M414 PolarHBondContact O-N 2.68Å; F411-F415 HydrophobicContact CE1-CB 4.4Å; F411-F415 HydrophobicContact CE2-CB 4.27Å; F411-F415 HydrophobicContact CE2-CD2 4.08Å; F411-F415 HydrophobicContact CZ-CB 4.14Å; F411-F415 AromaticContact CZ-CD2 3.8Å; F411-F415 HydrophobicContact CZ-CD2 3.8Å; F411-F415 HydrophobicContact CZ-CG 4.09Å; F411-F415 WeakPolarHBondContact O-CB 3.37Å; F411-F415 PolarHBondContact O-N 3.24Å
412	A	98.6	Very high	97.9	Very high	42 Å²	42	42.2 Å²	42.2	35%	0.347	22%	0.215	S	C	.	.	H	α-helix	trans	-61.4	-44.8	-175.5	0	0	0	0	0	112.3	K408 I409 F415 I416	K408-A412 PolarHBondContact O-N 3.11Å; I409-A412 PolarHBondContact O-N 2.78Å; I409-A412 VanDerWaalsContact O-N 3.11Å; A412-F415 PolarHBondContact O-N 2.65Å; A412-I416 WeakPolarHBondContact O-CB 3.35Å; A412-I416 VanDerWaalsContact O-CG1 3.3Å; A412-I416 WeakPolarHBondContact O-CG1 3.28Å; A412-I416 PolarHBondContact O-N 2.88Å
413	I	98.6	Very high	98	Very high	46 Å²	46	46.4 Å²	46.4	24%	0.236	23%	0.233	C	C	.	.	H	α-helix	trans	-63.3	-48.4	177.9	-63.7	173.7	0	0	0	110.2	I409 F411 I416 G417 I457 T460 A461 L464	I409-I413 HydrophobicContact CG2-CD1 3.65Å; I409-I413 HydrophobicContact CG2-CG1 4.19Å; I409-I413 WeakPolarHBondContact O-CG1 3.36Å; I409-I413 PolarHBondContact O-N 2.91Å; F411-I413 PolarHBondContact O-N 3.31Å; I413-I416 PolarHBondContact O-N 3.14Å; I413-G417 PolarHBondContact O-N 3.39Å; I413-I457 HydrophobicContact CG2-CG2 3.87Å; I413-I457 WeakPolarHBondContact CG2-O 3.45Å; I413-T460 WeakPolarHBondContact CG2-OG1 3.33Å; I413-A461 HydrophobicContact CB-CB 4.22Å; I413-A461 HydrophobicContact CG2-CB 3.82Å; I413-L464 HydrophobicContact CD1-CD2 4.05Å
414	M	98.1	Very high	98.1	Very high	16 Å²	16	44.6 Å²	44.6	8%	0.079	22%	0.223	C	C	.	.	H	α-helix	trans	-61.9	-47.5	178.9	-174.3	64.9	79.1	0	0	111.1	W337 F384 H410 F411 I416 G417 V418 A461 V462	W337-M414 HydrophobicContact CH2-CB 3.63Å; W337-M414 HydrophobicContact CH2-CG 3.7Å; W337-M414 HydrophobicContact CZ2-CB 4.41Å; W337-M414 HydrophobicContact CZ3-CB 4.38Å; W337-M414 HydrophobicContact CZ3-CG 4.09Å; F384-M414 HydrophobicContact CE2-CG 4.14Å; F384-M414 HydrophobicContact CZ-CG 4.36Å; H410-M414 WeakPolarHBondContact O-CB 3.24Å; H410-M414 PolarHBondContact O-N 2.94Å; F411-M414 PolarHBondContact O-N 2.68Å; M414-I416 VanDerWaalsContact C-N 3.33Å; M414-I416 PolarHBondContact O-N 3.44Å; M414-G417 PolarHBondContact O-N 3.3Å; M414-V418 HydrophobicContact CG-CG1 4.06Å; M414-V418 WeakPolarHBondContact O-CG1 3.44Å; M414-V418 WeakPolarHBondContact O-CG2 3.21Å; M414-V418 PolarHBondContact O-N 2.94Å; M414-V418 HydrophobicContact SD-CG1 3.62Å; M414-A461 HydrophobicContact CB-CB 3.84Å; M414-A461 HydrophobicContact CE-CB 3.72Å; M414-A461 HydrophobicContact SD-CB 4.22Å; M414-V462 HydrophobicContact CE-CG2 4.2Å
415	F	98.3	Very high	98.2	Very high	56 Å²	56	41.2 Å²	41.2	25%	0.246	21%	0.207	C	C	.	.	H	α-helix	trans	-57.5	-45.2	-178.9	-176.3	-90	0	0	0	112	F343 L344 F384 F411 A412 N419	F343-F415 HydrophobicContact CD1-CE2 4.31Å; F343-F415 HydrophobicContact CD1-CZ 4.09Å; F343-F415 HydrophobicContact CE1-CZ 4.28Å; L344-F415 HydrophobicContact CD1-CD2 3.73Å; L344-F415 HydrophobicContact CD1-CE2 3.56Å; L344-F415 HydrophobicContact CD2-CE2 4.08Å; L344-F415 HydrophobicContact CD2-CZ 4.33Å; L344-F415 HydrophobicContact CG-CE2 3.88Å; F384-F415 HydrophobicContact CE1-CD2 4.05Å; F384-F415 HydrophobicContact CZ-CD2 4.39Å; F411-F415 HydrophobicContact CE1-CB 4.4Å; F411-F415 HydrophobicContact CE2-CB 4.27Å; F411-F415 HydrophobicContact CE2-CD2 4.08Å; F411-F415 HydrophobicContact CZ-CB 4.14Å; F411-F415 AromaticContact CZ-CD2 3.8Å; F411-F415 HydrophobicContact CZ-CD2 3.8Å; F411-F415 HydrophobicContact CZ-CG 4.09Å; F411-F415 WeakPolarHBondContact O-CB 3.37Å; F411-F415 PolarHBondContact O-N 3.24Å; A412-F415 PolarHBondContact O-N 2.65Å; F415-N419 PolarHBondContact O-N 3.47Å; F415-N419 PolarHBondContact O-ND2 2.97Å
416	I	98.4	Very high	98.3	Very high	92 Å²	92	37.5 Å²	37.5	47%	0.472	18%	0.184	S	C	.	.	H	α-helix	trans	-67	-47.8	176.1	-67.6	167.4	0	0	0	110.5	A412 I413 M414 V418 N419 L420	A412-I416 WeakPolarHBondContact O-CB 3.35Å; A412-I416 VanDerWaalsContact O-CG1 3.3Å; A412-I416 WeakPolarHBondContact O-CG1 3.28Å; A412-I416 PolarHBondContact O-N 2.88Å; I413-I416 PolarHBondContact O-N 3.14Å; M414-I416 VanDerWaalsContact C-N 3.33Å; M414-I416 PolarHBondContact O-N 3.44Å; I416-V418 PolarHBondContact O-N 3.45Å; I416-N419 PolarHBondContact O-N 3.34Å; I416-L420 HydrophobicContact CG2-CD1 3.75Å; I416-L420 HydrophobicContact CG2-CG 4.33Å; I416-L420 WeakPolarHBondContact O-CB 3.36Å; I416-L420 WeakPolarHBondContact O-CG 3.35Å; I416-L420 PolarHBondContact O-N 2.91Å
417	G	98.2	Very high	98.3	Very high	0 Å²	0	36.9 Å²	36.9	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-58.9	-49.3	-177.3	0	0	0	0	0	113.2	I413 M414 N419 L420 T421 G454 S458	I413-G417 PolarHBondContact O-N 3.39Å; M414-G417 PolarHBondContact O-N 3.3Å; G417-N419 PolarHBondContact O-N 3.08Å; G417-L420 PolarHBondContact O-N 2.95Å; G417-T421 WeakPolarHBondContact O-CB 3.43Å; G417-T421 PolarHBondContact O-N 3.33Å; G417-T421 PolarHBondContact O-OG1 3.29Å; G417-G454 CarbonylContact C-O 3.58Å; G417-G454 WeakPolarHBondContact CA-O 3.39Å; G417-G454 CarbonylContact O-C 3.58Å; G417-G454 WeakPolarHBondContact O-CA 3.35Å; G417-S458 WeakPolarHBondContact CA-OG 3.38Å
418	V	97.3	Very high	98.3	Very high	5 Å²	5	36.9 Å²	36.9	3%	0.03	18%	0.183	C	C	.	.	H	α-helix	trans	-68	-36.8	-178.4	-59.6	0	0	0	0	112.1	M380 F384 M414 I416 T421 F422 S458	M380-V418 HydrophobicContact CG-CB 4.26Å; M380-V418 HydrophobicContact CG-CG2 3.74Å; M380-V418 HydrophobicContact SD-CB 4.47Å; M380-V418 HydrophobicContact SD-CG2 3.89Å; F384-V418 HydrophobicContact CE2-CG2 4Å; F384-V418 HydrophobicContact CZ-CG2 3.93Å; M414-V418 HydrophobicContact CG-CG1 4.06Å; M414-V418 WeakPolarHBondContact O-CG1 3.44Å; M414-V418 WeakPolarHBondContact O-CG2 3.21Å; M414-V418 PolarHBondContact O-N 2.94Å; M414-V418 HydrophobicContact SD-CG1 3.62Å; I416-V418 PolarHBondContact O-N 3.45Å; V418-T421 WeakPolarHBondContact O-CB 3.36Å; V418-T421 PolarHBondContact O-N 3.23Å; V418-F422 HydrophobicContact CB-CD2 4.16Å; V418-F422 HydrophobicContact CB-CE2 4.25Å; V418-F422 WeakPolarHBondContact O-CD2 3.44Å; V418-F422 PolarHBondContact O-N 2.93Å; V418-S458 PolarHBondContact N-OG 3.18Å
419	N	98.1	Very high	98.3	Very high	31 Å²	31	33 Å²	33	17%	0.166	17%	0.167	C	C	.	.	H	α-helix	trans	-68.4	-43.3	176.1	-82.5	-81.9	0	0	0	111.2	L344 Y376 F415 I416 G417 T421 F422 F423	L344-N419 VanDerWaalsContact CD2-ND2 3.33Å; L344-N419 WeakPolarHBondContact CD2-ND2 3.31Å; L344-N419 VanDerWaalsContact CD2-OD1 3.23Å; L344-N419 WeakPolarHBondContact CD2-OD1 3.4Å; Y376-N419 PolarHBondContact OH-OD1 2.98Å; F415-N419 PolarHBondContact O-N 3.47Å; F415-N419 PolarHBondContact O-ND2 2.97Å; I416-N419 PolarHBondContact O-N 3.34Å; G417-N419 PolarHBondContact O-N 3.08Å; N419-T421 PolarHBondContact O-N 2.8Å; N419-F422 PolarHBondContact O-N 2.74Å; N419-F423 WeakPolarHBondContact O-CB 3.43Å; N419-F423 PolarHBondContact O-N 2.99Å
420	L	97.9	Very high	98.3	Very high	67 Å²	67	34.6 Å²	34.6	35%	0.351	18%	0.175	S	C	.	.	H	α-helix	trans	-63.1	-30.1	173.1	-73.2	176.5	0	0	0	112.2	I416 G417 P424 S451 I457	I416-L420 HydrophobicContact CG2-CD1 3.75Å; I416-L420 HydrophobicContact CG2-CG 4.33Å; I416-L420 WeakPolarHBondContact O-CB 3.36Å; I416-L420 WeakPolarHBondContact O-CG 3.35Å; I416-L420 PolarHBondContact O-N 2.91Å; G417-L420 PolarHBondContact O-N 2.95Å; L420-P424 WeakPolarHBondContact O-CD 3.36Å; L420-P424 VanDerWaalsContact O-CG 3.24Å; L420-P424 WeakPolarHBondContact O-CG 3.41Å; L420-S451 WeakPolarHBondContact O-CA 3.27Å; L420-I457 HydrophobicContact CD1-CD1 3.73Å
421	T	98.3	Very high	98.2	Very high	5 Å²	5	37.4 Å²	37.4	3%	0.031	20%	0.195	C	C	.	.	H	α-helix	trans	-70.6	-56.8	175.8	-52.4	0	0	0	0	111.4	G417 V418 N419 Q425 S451 G454 S455	G417-T421 WeakPolarHBondContact O-CB 3.43Å; G417-T421 PolarHBondContact O-N 3.33Å; G417-T421 PolarHBondContact O-OG1 3.29Å; V418-T421 WeakPolarHBondContact O-CB 3.36Å; V418-T421 PolarHBondContact O-N 3.23Å; N419-T421 PolarHBondContact O-N 2.8Å; T421-Q425 PolarHBondContact O-NE2 3.18Å; T421-S451 WeakPolarHBondContact CA-O 3.22Å; T421-S451 VanDerWaalsContact O-CB 3.25Å; T421-S451 WeakPolarHBondContact O-CB 3.32Å; T421-S451 PolarHBondContact O-OG 3.03Å; T421-G454 WeakPolarHBondContact OG1-CA 3.22Å; T421-G454 PolarHBondContact OG1-O 3.05Å; T421-S455 WeakPolarHBondContact OG1-CA 3.31Å; T421-S455 PolarHBondContact OG1-N 3.03Å
422	F	98.4	Very high	98.2	Very high	24 Å²	24	37.9 Å²	37.9	11%	0.105	21%	0.208	C	C	.	.	H	α-helix	trans	-100.3	-24.3	-163.6	-58.6	-62.8	0	0	0	113.8	H375 Y376 M380 V418 N419 Q425	H375-F422 HydrophobicContact CB-CB 4.44Å; H375-F422 HydrophobicContact CB-CD1 3.42Å; H375-F422 VanDerWaalsContact CB-CD1 3.42Å; H375-F422 HydrophobicContact CB-CD2 4.03Å; H375-F422 HydrophobicContact CB-CE1 3.52Å; H375-F422 HydrophobicContact CB-CE2 4.1Å; H375-F422 HydrophobicContact CB-CG 3.7Å; H375-F422 HydrophobicContact CB-CZ 3.86Å; H375-F422 AromaticContact CD2-CE1 3.19Å; H375-F422 WeakPolarHBondContact CD2-CE1 3.44Å; H375-F422 AromaticContact CD2-CZ 3.34Å; H375-F422 WeakPolarHBondContact CD2-CZ 3.49Å; H375-F422 AromaticContact CG-CD1 3.67Å; H375-F422 AromaticContact CG-CE1 3.32Å; H375-F422 AromaticContact CG-CZ 3.79Å; H375-F422 AromaticContact NE2-CE1 3.91Å; Y376-F422 HydrophobicContact CD2-CB 4.03Å; Y376-F422 HydrophobicContact CE2-CB 3.71Å; M380-F422 HydrophobicContact CE-CB 3.78Å; M380-F422 HydrophobicContact CE-CD2 3.53Å; M380-F422 HydrophobicContact CE-CG 4.03Å; V418-F422 HydrophobicContact CB-CD2 4.16Å; V418-F422 HydrophobicContact CB-CE2 4.25Å; V418-F422 WeakPolarHBondContact O-CD2 3.44Å; V418-F422 PolarHBondContact O-N 2.93Å; N419-F422 PolarHBondContact O-N 2.74Å; F422-Q425 WeakPolarHBondContact O-CB 3.49Å; F422-Q425 PolarHBondContact O-N 3.13Å
423	F	98.3	Very high	98.1	Very high	99 Å²	99	36 Å²	36	43%	0.434	19%	0.192	S	C	.	.	H	α-helix	trans	-62	-46.2	177.8	-164.2	-105.7	0	0	0	112	Y376 N419 Q425 H426 F427	Y376-F423 WeakPolarHBondContact OH-CB 3.42Å; Y376-F423 WeakPolarHBondContact OH-CD2 3.45Å; N419-F423 WeakPolarHBondContact O-CB 3.43Å; N419-F423 PolarHBondContact O-N 2.99Å; F423-Q425 PolarHBondContact O-N 3.25Å; F423-Q425 VanDerWaalsContact O-N 3.13Å; F423-H426 PolarHBondContact O-N 3.3Å; F423-H426 VanDerWaalsContact O-N 3.16Å; F423-H426 PolarHBondContact O-ND1 2.66Å; F423-F427 AromaticContact CD1-CE2 3.94Å; F423-F427 HydrophobicContact CD1-CE2 3.94Å; F423-F427 HydrophobicContact CD1-CZ 4.37Å; F423-F427 AromaticContact CE1-CE2 3.75Å; F423-F427 HydrophobicContact CE1-CE2 3.75Å; F423-F427 AromaticContact CE1-CZ 3.72Å; F423-F427 HydrophobicContact CE1-CZ 3.72Å; F423-F427 HydrophobicContact CZ-CZ 4.34Å
424	P	98.4	Very high	98.1	Very high	8 Å²	8	36.1 Å²	36.1	5%	0.052	20%	0.196	C	C	.	.	H	α-helix	trans	-59.4	-25.3	176.2	-27.3	38.7	0	0	0	114.4	L420 H426 F427 L428 W447 L450	L420-P424 WeakPolarHBondContact O-CD 3.36Å; L420-P424 VanDerWaalsContact O-CG 3.24Å; L420-P424 WeakPolarHBondContact O-CG 3.41Å; P424-H426 VanDerWaalsContact C-N 3.25Å; P424-H426 PolarHBondContact O-N 3.28Å; P424-F427 WeakPolarHBondContact O-CB 3.45Å; P424-F427 PolarHBondContact O-N 3.34Å; P424-L428 PolarHBondContact O-N 3.41Å; P424-L428 VanDerWaalsContact O-N 3.09Å; P424-W447 HydrophobicContact CB-CB 4.06Å; P424-W447 HydrophobicContact CB-CD2 4.41Å; P424-W447 HydrophobicContact CB-CE3 3.91Å; P424-W447 HydrophobicContact CG-CE3 4.47Å; P424-L450 HydrophobicContact CG-CB 4.21Å
425	Q	98.5	Very high	98.1	Very high	6 Å²	6	37.4 Å²	37.4	3%	0.028	20%	0.199	C	C	.	.	H	α-helix	trans	-68.4	-24	-179.2	-64.6	-177.9	6.5	0	0	112.8	Y368 A372 T421 F422 F423 F427 L428 G429 S451	Y368-Q425 CarbonylContact C-O 3.47Å; Y368-Q425 HydrophobicContact CD1-CB 4.06Å; Y368-Q425 HydrophobicContact CD1-CG 3.85Å; Y368-Q425 HydrophobicContact CE1-CG 4.45Å; A372-Q425 HydrophobicContact CB-CB 3.72Å; T421-Q425 PolarHBondContact O-NE2 3.18Å; F422-Q425 WeakPolarHBondContact O-CB 3.49Å; F422-Q425 PolarHBondContact O-N 3.13Å; F423-Q425 PolarHBondContact O-N 3.25Å; F423-Q425 VanDerWaalsContact O-N 3.13Å; Q425-F427 VanDerWaalsContact C-N 3.33Å; Q425-L428 HydrophobicContact CG-CD1 4.28Å; Q425-L428 PolarHBondContact O-N 3.2Å; Q425-G429 PolarHBondContact O-N 3.3Å; Q425-S451 PolarHBondContact NE2-OG 3.42Å
426	H	98.6	Very high	97.9	Very high	11 Å²	11	38 Å²	38	5%	0.051	20%	0.2	C	C	.	.	H	α-helix	trans	-63	-41.3	168.8	-63.8	101	0	0	0	111.2	Y369 A372 Y376 F423 P424 G429 L430	Y369-H426 HydrophobicContact CD2-CB 4.16Å; Y369-H426 AromaticContact CD2-CD2 3.96Å; Y369-H426 HydrophobicContact CE2-CB 4.23Å; Y369-H426 AromaticContact CE2-CD2 3.83Å; A372-H426 WeakPolarHBondContact CB-NE2 3.38Å; Y376-H426 AromaticContact CD2-CE1 3.58Å; Y376-H426 AromaticContact CE2-CE1 3.58Å; F423-H426 PolarHBondContact O-N 3.3Å; F423-H426 VanDerWaalsContact O-N 3.16Å; F423-H426 PolarHBondContact O-ND1 2.66Å; P424-H426 VanDerWaalsContact C-N 3.25Å; P424-H426 PolarHBondContact O-N 3.28Å; H426-G429 PolarHBondContact O-N 3Å; H426-L430 WeakPolarHBondContact O-CB 3.23Å; H426-L430 VanDerWaalsContact O-CG 3.25Å; H426-L430 WeakPolarHBondContact O-CG 3.45Å; H426-L430 PolarHBondContact O-N 3.43Å
427	F	98.4	Very high	97.8	Very high	79 Å²	79	40.2 Å²	40.2	35%	0.346	20%	0.204	S	C	.	.	H	α-helix	trans	-67.3	-41.2	176.8	-56.9	-54.7	0	0	0	111.5	F423 P424 Q425 G429 L430 S431 W447	F423-F427 AromaticContact CD1-CE2 3.94Å; F423-F427 HydrophobicContact CD1-CE2 3.94Å; F423-F427 HydrophobicContact CD1-CZ 4.37Å; F423-F427 AromaticContact CE1-CE2 3.75Å; F423-F427 HydrophobicContact CE1-CE2 3.75Å; F423-F427 AromaticContact CE1-CZ 3.72Å; F423-F427 HydrophobicContact CE1-CZ 3.72Å; F423-F427 HydrophobicContact CZ-CZ 4.34Å; P424-F427 WeakPolarHBondContact O-CB 3.45Å; P424-F427 PolarHBondContact O-N 3.34Å; Q425-F427 VanDerWaalsContact C-N 3.33Å; F427-G429 VanDerWaalsContact C-N 3.32Å; F427-G429 PolarHBondContact O-N 3.2Å; F427-L430 PolarHBondContact O-N 2.98Å; F427-S431 WeakPolarHBondContact O-CB 3.43Å; F427-S431 PolarHBondContact O-N 3.13Å; F427-S431 PolarHBondContact O-OG 3.23Å; F427-W447 HydrophobicContact CB-CD2 4.33Å; F427-W447 HydrophobicContact CB-CG 4.37Å; F427-W447 HydrophobicContact CD2-CD2 4.28Å; F427-W447 HydrophobicContact CD2-CE3 4.34Å; F427-W447 HydrophobicContact CD2-CH2 4.15Å; F427-W447 HydrophobicContact CD2-CZ2 4.06Å; F427-W447 HydrophobicContact CD2-CZ3 4.29Å; F427-W447 HydrophobicContact CE2-CH2 4.45Å; F427-W447 HydrophobicContact CG-CZ2 4.38Å
428	L	98.4	Very high	97.7	Very high	0 Å²	0	40.7 Å²	40.7	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-55.5	-48.2	172.2	-71.1	174	0	0	0	111.3	Y368 P424 Q425 S431 G432 M433 Y444 W447	Y368-L428 HydrophobicContact CD1-CD1 4.36Å; Y368-L428 HydrophobicContact CG-CB 4.33Å; P424-L428 PolarHBondContact O-N 3.41Å; P424-L428 VanDerWaalsContact O-N 3.09Å; Q425-L428 HydrophobicContact CG-CD1 4.28Å; Q425-L428 PolarHBondContact O-N 3.2Å; L428-S431 WeakPolarHBondContact CA-OG 3.27Å; L428-S431 PolarHBondContact O-N 2.99Å; L428-S431 PolarHBondContact O-OG 2.89Å; L428-G432 PolarHBondContact O-N 2.81Å; L428-M433 HydrophobicContact CB-CB 4.06Å; L428-M433 HydrophobicContact CB-SD 3.93Å; L428-M433 HydrophobicContact CD1-SD 3.78Å; L428-M433 HydrophobicContact CD2-SD 3.67Å; L428-M433 HydrophobicContact CG-SD 4Å; L428-M433 VanDerWaalsContact O-CB 3.29Å; L428-M433 WeakPolarHBondContact O-CB 3.19Å; L428-M433 PolarHBondContact O-N 3.11Å; L428-Y444 HydrophobicContact CD2-CD1 3.95Å; L428-Y444 HydrophobicContact CD2-CG 4.1Å; L428-W447 HydrophobicContact CD1-CB 4.03Å; L428-W447 HydrophobicContact CD2-CB 3.58Å; L428-W447 HydrophobicContact CD2-CG 4.27Å; L428-W447 HydrophobicContact CG-CB 3.59Å; L428-W447 HydrophobicContact CG-CG 4.37Å
429	G	98.2	Very high	97.7	Very high	1 Å²	1	43.6 Å²	43.6	1%	0.01	22%	0.222	C	C	.	.	H	α-helix	trans	-63.7	-45.6	178	0	0	0	0	0	114	Y369 Q425 H426 F427 S431 G432	Y369-G429 VanDerWaalsContact N-CA 3.34Å; Q425-G429 PolarHBondContact O-N 3.3Å; H426-G429 PolarHBondContact O-N 3Å; F427-G429 VanDerWaalsContact C-N 3.32Å; F427-G429 PolarHBondContact O-N 3.2Å; G429-S431 PolarHBondContact O-N 2.61Å; G429-G432 PolarHBondContact O-N 3.38Å
430	L	97.8	Very high	97.6	Very high	110 Å²	110	42.7 Å²	42.7	58%	0.576	22%	0.217	S	C	*	.	H	α-helix	trans	-62.5	-29.2	176.1	-71.9	169.7	0	0	0	112.5	L364 Y369 H426 F427 G432	L364-L430 HydrophobicContact CD2-CD2 4.03Å; Y369-L430 HydrophobicContact CD2-CD2 4.03Å; Y369-L430 HydrophobicContact CD2-CG 3.83Å; Y369-L430 HydrophobicContact CE2-CD1 4.3Å; Y369-L430 HydrophobicContact CE2-CD2 3.96Å; Y369-L430 HydrophobicContact CE2-CG 3.97Å; H426-L430 WeakPolarHBondContact O-CB 3.23Å; H426-L430 VanDerWaalsContact O-CG 3.25Å; H426-L430 WeakPolarHBondContact O-CG 3.45Å; H426-L430 PolarHBondContact O-N 3.43Å; F427-L430 PolarHBondContact O-N 2.98Å; L430-G432 VanDerWaalsContact C-N 3.28Å
431	S	97.4	Very high	97.6	Very high	60 Å²	60	43.5 Å²	43.5	42%	0.42	23%	0.226	S	C	.	.	T	Hydrogen-bonded Turn	trans	-81.3	-3.1	173.2	61.2	0	0	0	0	114.2	F427 L428 G429 Y444	F427-S431 WeakPolarHBondContact O-CB 3.43Å; F427-S431 PolarHBondContact O-N 3.13Å; F427-S431 PolarHBondContact O-OG 3.23Å; L428-S431 WeakPolarHBondContact CA-OG 3.27Å; L428-S431 PolarHBondContact O-N 2.99Å; L428-S431 PolarHBondContact O-OG 2.89Å; G429-S431 PolarHBondContact O-N 2.61Å; S431-Y444 PolarHBondContact O-OH 2.85Å; S431-Y444 WeakPolarHBondContact OG-CE1 3.49Å
432	G	97.4	Very high	97.5	Very high	37 Å²	37	49.3 Å²	49.3	38%	0.381	26%	0.257	S	S	.	.	T	Hydrogen-bonded Turn	trans	90.3	18	176.7	0	0	0	0	0	115.2	L428 G429 L430 P434	L428-G432 PolarHBondContact O-N 2.81Å; G429-G432 PolarHBondContact O-N 3.38Å; L430-G432 VanDerWaalsContact C-N 3.28Å; G432-P434 VanDerWaalsContact O-CD 3.31Å; G432-P434 WeakPolarHBondContact O-CD 3.14Å
433	M	98.3	Very high	97.4	Very high	2 Å²	2	52.3 Å²	52.3	1%	0.01	29%	0.286	C	S	.	.	P	Polyproline II helix	trans	-67.8	118.8	175.6	-172.5	-173.1	177.5	0	0	110.1	T367 Y368 L428 Y440 Y444 N448	T367-M433 CarbonylContact C-O 3.38Å; T367-M433 VanDerWaalsContact CA-O 3.27Å; T367-M433 WeakPolarHBondContact CA-O 3.24Å; T367-M433 WeakPolarHBondContact CB-O 3.42Å; Y368-M433 HydrophobicContact CD2-CB 4.21Å; Y368-M433 HydrophobicContact CD2-CE 4.11Å; Y368-M433 HydrophobicContact CD2-CG 3.76Å; Y368-M433 HydrophobicContact CD2-SD 3.68Å; Y368-M433 HydrophobicContact CE2-CE 3.5Å; Y368-M433 HydrophobicContact CE2-CG 4.04Å; Y368-M433 HydrophobicContact CE2-SD 3.74Å; Y368-M433 HydrophobicContact CG-SD 4.14Å; Y368-M433 PolarHBondContact N-O 3.02Å; L428-M433 HydrophobicContact CB-CB 4.06Å; L428-M433 HydrophobicContact CB-SD 3.93Å; L428-M433 HydrophobicContact CD1-SD 3.78Å; L428-M433 HydrophobicContact CD2-SD 3.67Å; L428-M433 HydrophobicContact CG-SD 4Å; L428-M433 VanDerWaalsContact O-CB 3.29Å; L428-M433 WeakPolarHBondContact O-CB 3.19Å; L428-M433 PolarHBondContact O-N 3.11Å; M433-Y440 HydrophobicContact CE-CD1 3.78Å; M433-Y440 HydrophobicContact CE-CG 3.85Å; M433-Y444 HydrophobicContact CB-CD1 4.14Å; M433-Y444 HydrophobicContact CB-CD2 4.15Å; M433-Y444 HydrophobicContact CB-CE1 4.04Å; M433-Y444 HydrophobicContact CB-CE2 4.01Å; M433-Y444 HydrophobicContact CB-CG 4.19Å; M433-Y444 HydrophobicContact CG-CD2 3.94Å; M433-Y444 HydrophobicContact CG-CE2 4.12Å; M433-Y444 HydrophobicContact CG-CG 4.19Å; M433-Y444 HydrophobicContact SD-CD2 4.47Å; M433-Y444 HydrophobicContact SD-CG 4.3Å; M433-N448 WeakPolarHBondContact CE-ND2 3.35Å; M433-N448 PolarHBondContact SD-ND2 3.28Å; M433-N448 VanDerWaalsContact SD-ND2 3.44Å
434	P	97.8	Very high	97.4	Very high	49 Å²	49	49.4 Å²	49.4	32%	0.318	27%	0.273	S	S	.	.	B	Isolated β-bridge	trans	-77.4	152.2	-179.3	33.8	-36.5	0	0	0	111.8	D366 Y368 G432 Y437	D366-P434 CarbonylContact O-C 3.59Å; D366-P434 WeakPolarHBondContact O-CA 3.31Å; Y368-P434 WeakPolarHBondContact CD2-O 3.23Å; Y368-P434 VanDerWaalsContact CE2-O 3.23Å; Y368-P434 WeakPolarHBondContact CE2-O 3.17Å; G432-P434 VanDerWaalsContact O-CD 3.31Å; G432-P434 WeakPolarHBondContact O-CD 3.14Å; P434-Y437 HydrophobicContact CB-CD2 3.77Å; P434-Y437 HydrophobicContact CB-CE2 3.54Å; P434-Y437 HydrophobicContact CG-CD2 3.56Å; P434-Y437 HydrophobicContact CG-CE2 3.6Å; P434-Y437 HydrophobicContact CG-CG 4.21Å
435	R	97.3	Very high	97.4	Very high	43 Å²	43	50.2 Å²	50.2	16%	0.162	28%	0.277	C	S	.	.	S	Bend	trans	-83.1	157.7	177.4	74.4	-174.9	-179.1	171.1	-4.2	111.9	D366 V371 Y437	D366-R435 HydrophobicContact CB-CG 4.42Å; D366-R435 VanDerWaalsContact O-CG 3.3Å; D366-R435 WeakPolarHBondContact O-CG 3.29Å; D366-R435 PolarHBondContact O-N 3.06Å; D366-R435 IonicContact OD1-CZ 3.62Å; D366-R435 IonicContact OD1-NE 3.31Å; D366-R435 PolarHBondContact OD1-NE 3.16Å; D366-R435 IonicContact OD1-NH2 2.96Å; D366-R435 PolarHBondContact OD1-NH2 2.92Å; V371-R435 HydrophobicContact CG2-CB 3.85Å; R435-Y437 VanDerWaalsContact O-CD2 3.22Å; R435-Y437 WeakPolarHBondContact O-CD2 3.16Å
436	R	95.6	Very high	97.3	Very high	68 Å²	68	54.2 Å²	54.2	26%	0.257	30%	0.302	S	S	.	.	S	Bend	trans	64	32.4	176.2	-54.4	172.4	-174.6	177.4	1.6	114.8	N52 V55	N52-R436 PolarHBondContact OD1-O 2.7Å; V55-R436 HydrophobicContact CG1-CG 4.46Å
437	Y	95.9	Very high	97.3	Very high	139 Å²	139	58.3 Å²	58.3	55%	0.545	32%	0.317	S	S	.	.			trans	-105.1	139.5	165.8	-70.7	-101.9	0	0	0	108.9	Y51 P434 R435 D439	Y51-Y437 VanDerWaalsContact CE1-O 3.23Å; Y51-Y437 WeakPolarHBondContact CE1-O 3.26Å; Y51-Y437 PolarHBondContact OH-O 3.31Å; P434-Y437 HydrophobicContact CB-CD2 3.77Å; P434-Y437 HydrophobicContact CB-CE2 3.54Å; P434-Y437 HydrophobicContact CG-CD2 3.56Å; P434-Y437 HydrophobicContact CG-CE2 3.6Å; P434-Y437 HydrophobicContact CG-CG 4.21Å; R435-Y437 VanDerWaalsContact O-CD2 3.22Å; R435-Y437 WeakPolarHBondContact O-CD2 3.16Å; Y437-D439 WeakPolarHBondContact CB-O 3.26Å
438	S	95.9	Very high	97.3	Very high	11 Å²	11	54.5 Å²	54.5	8%	0.077	30%	0.301	C	S	.	.	S	Bend	trans	-76.3	-27.6	175.6	40.9	0	0	0	0	112.4	D48	D48-S438 WeakPolarHBondContact OD1-CB 3.46Å; D48-S438 PolarHBondContact OD1-OG 3.32Å
439	D	96.6	Very high	97.3	Very high	65 Å²	65	57.4 Å²	57.4	35%	0.348	32%	0.315	S	S	.	.			trans	-130.3	162.9	180	-163.4	8	0	0	0	111.4	G42 Y437	G42-D439 PolarHBondContact N-OD1 3.04Å; G42-D439 PolarHBondContact N-OD2 2.81Å; Y437-D439 WeakPolarHBondContact CB-O 3.26Å
440	Y	96.6	Very high	97.3	Very high	12 Å²	12	60.6 Å²	60.6	5%	0.047	33%	0.332	C	S	.	.			trans	-152	152.9	-175.9	58	-97.7	0	0	0	113.5	L38 Q40 P41 M433 N448	L38-Y440 HydrophobicContact CB-CE1 4.13Å; L38-Y440 HydrophobicContact CD2-CD1 3.85Å; L38-Y440 HydrophobicContact CD2-CE1 3.99Å; L38-Y440 VanDerWaalsContact O-CE1 3.27Å; L38-Y440 WeakPolarHBondContact O-CE1 3.46Å; L38-Y440 PolarHBondContact O-OH 2.94Å; Q40-Y440 VanDerWaalsContact C-OH 3.27Å; Q40-Y440 WeakPolarHBondContact CA-OH 3.36Å; Q40-Y440 PolarHBondContact N-OH 3.22Å; P41-Y440 HydrophobicContact CG-CD2 4.33Å; P41-Y440 HydrophobicContact CG-CE2 3.76Å; M433-Y440 HydrophobicContact CE-CD1 3.78Å; M433-Y440 HydrophobicContact CE-CG 3.85Å; Y440-N448 HydrophobicContact CE1-CB 4.06Å; Y440-N448 HydrophobicContact CE2-CB 4.13Å; Y440-N448 VanDerWaalsContact OH-CB 3.22Å; Y440-N448 WeakPolarHBondContact OH-CB 3.26Å
441	P	97.1	Very high	97.3	Very high	85 Å²	85	55.3 Å²	55.3	55%	0.552	31%	0.305	S	S	*	.			trans	-58.5	142.8	174.5	-25.6	32.8	0	0	0	113.9	A443 Y444	P441-A443 PolarHBondContact O-N 3.16Å; P441-Y444 HydrophobicContact CB-CD2 4.28Å; P441-Y444 HydrophobicContact CB-CE2 4.34Å; P441-Y444 HydrophobicContact CG-CD2 4.31Å; P441-Y444 HydrophobicContact CG-CE2 4.06Å; P441-Y444 PolarHBondContact O-N 3.45Å
442	D	96.4	Very high	97.3	Very high	126 Å²	126	52.8 Å²	52.8	67%	0.674	29%	0.287	S	S	*	.	G	3₁₀ helix	trans	-51.1	-26.3	-176.9	-62.3	4.5	0	0	0	114.7	Y444 T445	D442-Y444 PolarHBondContact O-N 3Å; D442-Y444 VanDerWaalsContact O-N 3.15Å; D442-T445 WeakPolarHBondContact CA-OG1 3.19Å; D442-T445 VanDerWaalsContact O-CB 3.23Å; D442-T445 WeakPolarHBondContact O-CB 3.11Å; D442-T445 PolarHBondContact O-N 3.46Å; D442-T445 VanDerWaalsContact O-N 3.1Å; D442-T445 PolarHBondContact O-OG1 3.44Å
443	A	97.1	Very high	97.4	Very high	87 Å²	87	54.3 Å²	54.3	72%	0.719	29%	0.289	S	S	*	.	G	3₁₀ helix	trans	-57.5	-25.4	175.8	0	0	0	0	0	113.7	P441	P441-A443 PolarHBondContact O-N 3.16Å
444	Y	97.7	Very high	97.4	Very high	39 Å²	39	54.2 Å²	54.2	15%	0.153	29%	0.288	C	S	.	.	G	3₁₀ helix	trans	-92.7	-2.8	-179.4	-58	-48.8	0	0	0	113.9	L428 S431 M433 P441 D442 T446 W447 N448	L428-Y444 HydrophobicContact CD2-CD1 3.95Å; L428-Y444 HydrophobicContact CD2-CG 4.1Å; S431-Y444 PolarHBondContact O-OH 2.85Å; S431-Y444 WeakPolarHBondContact OG-CE1 3.49Å; M433-Y444 HydrophobicContact CB-CD1 4.14Å; M433-Y444 HydrophobicContact CB-CD2 4.15Å; M433-Y444 HydrophobicContact CB-CE1 4.04Å; M433-Y444 HydrophobicContact CB-CE2 4.01Å; M433-Y444 HydrophobicContact CB-CG 4.19Å; M433-Y444 HydrophobicContact CG-CD2 3.94Å; M433-Y444 HydrophobicContact CG-CE2 4.12Å; M433-Y444 HydrophobicContact CG-CG 4.19Å; M433-Y444 HydrophobicContact SD-CD2 4.47Å; M433-Y444 HydrophobicContact SD-CG 4.3Å; P441-Y444 HydrophobicContact CB-CD2 4.28Å; P441-Y444 HydrophobicContact CB-CE2 4.34Å; P441-Y444 HydrophobicContact CG-CD2 4.31Å; P441-Y444 HydrophobicContact CG-CE2 4.06Å; P441-Y444 PolarHBondContact O-N 3.45Å; D442-Y444 PolarHBondContact O-N 3Å; D442-Y444 VanDerWaalsContact O-N 3.15Å; Y444-T446 PolarHBondContact O-N 2.96Å; Y444-W447 PolarHBondContact O-N 3.23Å; Y444-N448 PolarHBondContact O-N 2.89Å; Y444-N448 PolarHBondContact O-ND2 3.35Å
445	T	97.6	Very high	97.4	Very high	24 Å²	24	52.3 Å²	52.3	15%	0.147	28%	0.276	C	S	.	.	H	α-helix	trans	-58	-47.5	-171.4	-56.8	0	0	0	0	113.1	P41 D442 W447 N448 I449	P41-T445 HydrophobicContact CG-CG2 4.4Å; P41-T445 WeakPolarHBondContact CG-OG1 3.2Å; D442-T445 WeakPolarHBondContact CA-OG1 3.19Å; D442-T445 VanDerWaalsContact O-CB 3.23Å; D442-T445 WeakPolarHBondContact O-CB 3.11Å; D442-T445 PolarHBondContact O-N 3.46Å; D442-T445 VanDerWaalsContact O-N 3.1Å; D442-T445 PolarHBondContact O-OG1 3.44Å; T445-W447 PolarHBondContact O-N 3.4Å; T445-N448 PolarHBondContact O-N 2.85Å; T445-N448 VanDerWaalsContact O-N 3.17Å; T445-I449 HydrophobicContact CG2-CD1 3.55Å; T445-I449 HydrophobicContact CG2-CG1 4.09Å; T445-I449 WeakPolarHBondContact O-CG1 3.33Å; T445-I449 PolarHBondContact O-N 3.07Å
446	T	97.5	Very high	97.4	Very high	91 Å²	91	55.2 Å²	55.2	56%	0.558	29%	0.29	S	S	*	.	H	α-helix	trans	-56.3	-47.7	-175.7	-55.3	0	0	0	0	112.4	Y444 L450	Y444-T446 PolarHBondContact O-N 2.96Å; T446-L450 WeakPolarHBondContact O-CG 3.41Å; T446-L450 PolarHBondContact O-N 2.92Å
447	W	98.2	Very high	97.5	Very high	96 Å²	96	54.3 Å²	54.3	36%	0.364	29%	0.289	S	S	.	.	H	α-helix	trans	-74	-32	-178.8	-62.3	130.9	0	0	0	112.5	P424 F427 L428 Y444 T445 L450 S451	P424-W447 HydrophobicContact CB-CB 4.06Å; P424-W447 HydrophobicContact CB-CD2 4.41Å; P424-W447 HydrophobicContact CB-CE3 3.91Å; P424-W447 HydrophobicContact CG-CE3 4.47Å; F427-W447 HydrophobicContact CB-CD2 4.33Å; F427-W447 HydrophobicContact CB-CG 4.37Å; F427-W447 HydrophobicContact CD2-CD2 4.28Å; F427-W447 HydrophobicContact CD2-CE3 4.34Å; F427-W447 HydrophobicContact CD2-CH2 4.15Å; F427-W447 HydrophobicContact CD2-CZ2 4.06Å; F427-W447 HydrophobicContact CD2-CZ3 4.29Å; F427-W447 HydrophobicContact CE2-CH2 4.45Å; F427-W447 HydrophobicContact CG-CZ2 4.38Å; L428-W447 HydrophobicContact CD1-CB 4.03Å; L428-W447 HydrophobicContact CD2-CB 3.58Å; L428-W447 HydrophobicContact CD2-CG 4.27Å; L428-W447 HydrophobicContact CG-CB 3.59Å; L428-W447 HydrophobicContact CG-CG 4.37Å; Y444-W447 PolarHBondContact O-N 3.23Å; T445-W447 PolarHBondContact O-N 3.4Å; W447-L450 HydrophobicContact CE3-CD1 3.65Å; W447-L450 HydrophobicContact CZ3-CD1 3.67Å; W447-S451 VanDerWaalsContact O-CB 3.26Å; W447-S451 WeakPolarHBondContact O-CB 3.44Å; W447-S451 PolarHBondContact O-N 2.82Å
448	N	98.3	Very high	97.6	Very high	0 Å²	0	48.4 Å²	48.4	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-68.4	-41.8	174.5	-90.3	-59.5	0	0	0	112.8	R35 L38 M433 Y440 Y444 T445 L450 S451 S452	R35-N448 PolarHBondContact NH1-OD1 2.9Å; R35-N448 PolarHBondContact NH2-O 3.44Å; R35-N448 PolarHBondContact NH2-OD1 3.5Å; L38-N448 WeakPolarHBondContact O-CB 3.48Å; M433-N448 WeakPolarHBondContact CE-ND2 3.35Å; M433-N448 PolarHBondContact SD-ND2 3.28Å; M433-N448 VanDerWaalsContact SD-ND2 3.44Å; Y440-N448 HydrophobicContact CE1-CB 4.06Å; Y440-N448 HydrophobicContact CE2-CB 4.13Å; Y440-N448 VanDerWaalsContact OH-CB 3.22Å; Y440-N448 WeakPolarHBondContact OH-CB 3.26Å; Y444-N448 PolarHBondContact O-N 2.89Å; Y444-N448 PolarHBondContact O-ND2 3.35Å; T445-N448 PolarHBondContact O-N 2.85Å; T445-N448 VanDerWaalsContact O-N 3.17Å; N448-L450 PolarHBondContact O-N 3.04Å; N448-S451 PolarHBondContact O-N 3.3Å; N448-S452 WeakPolarHBondContact O-CB 3.1Å; N448-S452 PolarHBondContact O-N 3.01Å; N448-S452 PolarHBondContact O-OG 3.28Å; N448-S452 VanDerWaalsContact O-OG 3.12Å
449	I	98	Very high	97.7	Very high	60 Å²	60	50.5 Å²	50.5	31%	0.308	28%	0.279	S	S	.	.	H	α-helix	trans	-58.1	-49.9	173.6	-68.3	167.9	0	0	0	110	G39 T445 S451 S452 V453	G39-I449 VanDerWaalsContact O-CG1 3.22Å; G39-I449 WeakPolarHBondContact O-CG1 3.33Å; T445-I449 HydrophobicContact CG2-CD1 3.55Å; T445-I449 HydrophobicContact CG2-CG1 4.09Å; T445-I449 WeakPolarHBondContact O-CG1 3.33Å; T445-I449 PolarHBondContact O-N 3.07Å; I449-S451 VanDerWaalsContact C-N 3.31Å; I449-S451 PolarHBondContact O-N 3.19Å; I449-S452 PolarHBondContact O-N 2.86Å; I449-V453 HydrophobicContact CG2-CG2 4.35Å; I449-V453 WeakPolarHBondContact O-CG2 3.35Å; I449-V453 PolarHBondContact O-N 3.4Å
450	L	98.1	Very high	97.8	Very high	68 Å²	68	51 Å²	51	36%	0.356	28%	0.284	S	S	.	.	H	α-helix	trans	-60.2	-43.1	178.7	-73.3	173.2	0	0	0	111.7	P424 T446 W447 N448 S452 V453 G454	P424-L450 HydrophobicContact CG-CB 4.21Å; T446-L450 WeakPolarHBondContact O-CG 3.41Å; T446-L450 PolarHBondContact O-N 2.92Å; W447-L450 HydrophobicContact CE3-CD1 3.65Å; W447-L450 HydrophobicContact CZ3-CD1 3.67Å; N448-L450 PolarHBondContact O-N 3.04Å; L450-S452 VanDerWaalsContact C-N 3.34Å; L450-S452 PolarHBondContact O-N 3.13Å; L450-V453 PolarHBondContact O-N 3.21Å; L450-G454 PolarHBondContact O-N 3.46Å
451	S	98.4	Very high	97.8	Very high	0 Å²	0	50.4 Å²	50.4	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-61	-42.6	176.6	-175.7	0	0	0	0	111.9	L420 T421 Q425 W447 N448 I449 G454 S455	L420-S451 WeakPolarHBondContact O-CA 3.27Å; T421-S451 WeakPolarHBondContact CA-O 3.22Å; T421-S451 VanDerWaalsContact O-CB 3.25Å; T421-S451 WeakPolarHBondContact O-CB 3.32Å; T421-S451 PolarHBondContact O-OG 3.03Å; Q425-S451 PolarHBondContact NE2-OG 3.42Å; W447-S451 VanDerWaalsContact O-CB 3.26Å; W447-S451 WeakPolarHBondContact O-CB 3.44Å; W447-S451 PolarHBondContact O-N 2.82Å; N448-S451 PolarHBondContact O-N 3.3Å; I449-S451 VanDerWaalsContact C-N 3.31Å; I449-S451 PolarHBondContact O-N 3.19Å; S451-G454 PolarHBondContact O-N 3.26Å; S451-S455 PolarHBondContact O-N 3.43Å; S451-S455 VanDerWaalsContact O-N 3.12Å
452	S	98.3	Very high	97.8	Very high	6 Å²	6	47.8 Å²	47.8	4%	0.042	26%	0.264	C	S	.	.	H	α-helix	trans	-70.4	-39.3	178	-62.5	0	0	0	0	112.6	R35 N448 I449 L450 G454 S455 F456	R35-S452 PolarHBondContact NE-OG 2.93Å; R35-S452 PolarHBondContact NH2-OG 2.9Å; R35-S452 WeakPolarHBondContact O-CB 3.41Å; R35-S452 PolarHBondContact O-OG 2.84Å; N448-S452 WeakPolarHBondContact O-CB 3.1Å; N448-S452 PolarHBondContact O-N 3.01Å; N448-S452 PolarHBondContact O-OG 3.28Å; N448-S452 VanDerWaalsContact O-OG 3.12Å; I449-S452 PolarHBondContact O-N 2.86Å; L450-S452 VanDerWaalsContact C-N 3.34Å; L450-S452 PolarHBondContact O-N 3.13Å; S452-G454 VanDerWaalsContact C-N 3.32Å; S452-G454 PolarHBondContact O-N 2.59Å; S452-S455 WeakPolarHBondContact O-CB 3.43Å; S452-S455 PolarHBondContact O-N 2.95Å; S452-S455 VanDerWaalsContact O-N 3.1Å; S452-F456 WeakPolarHBondContact O-CD2 3.33Å; S452-F456 PolarHBondContact O-N 2.9Å; S452-F456 VanDerWaalsContact O-N 3.08Å
453	V	98.4	Very high	97.9	Very high	70 Å²	70	47.1 Å²	47.1	42%	0.424	26%	0.259	S	S	.	.	H	α-helix	trans	-58.9	-44.3	171.8	170.3	0	0	0	0	111	I449 L450 S455 F456 I457	I449-V453 HydrophobicContact CG2-CG2 4.35Å; I449-V453 WeakPolarHBondContact O-CG2 3.35Å; I449-V453 PolarHBondContact O-N 3.4Å; L450-V453 PolarHBondContact O-N 3.21Å; V453-S455 VanDerWaalsContact C-N 3.26Å; V453-S455 PolarHBondContact O-N 3.21Å; V453-F456 PolarHBondContact O-N 2.84Å; V453-I457 HydrophobicContact CG1-CD1 4.05Å; V453-I457 WeakPolarHBondContact O-CG1 3.38Å; V453-I457 PolarHBondContact O-N 3.41Å
454	G	98.4	Very high	98	Very high	0 Å²	0	44.3 Å²	44.3	0%	0	23%	0.231	C	C	.	.	H	α-helix	trans	-57.6	-38.8	174.3	0	0	0	0	0	112.9	G417 T421 L450 S451 S452 I457 S458	G417-G454 CarbonylContact C-O 3.58Å; G417-G454 WeakPolarHBondContact CA-O 3.39Å; G417-G454 CarbonylContact O-C 3.58Å; G417-G454 WeakPolarHBondContact O-CA 3.35Å; T421-G454 WeakPolarHBondContact OG1-CA 3.22Å; T421-G454 PolarHBondContact OG1-O 3.05Å; L450-G454 PolarHBondContact O-N 3.46Å; S451-G454 PolarHBondContact O-N 3.26Å; S452-G454 VanDerWaalsContact C-N 3.32Å; S452-G454 PolarHBondContact O-N 2.59Å; G454-I457 PolarHBondContact O-N 2.72Å; G454-S458 PolarHBondContact O-N 2.86Å; G454-S458 PolarHBondContact O-OG 3.13Å
455	S	97.9	Very high	98	Very high	9 Å²	9	43.4 Å²	43.4	6%	0.063	23%	0.229	C	C	.	.	H	α-helix	trans	-66.6	-42	178.9	-175.5	0	0	0	0	111.7	T421 S451 S452 V453 I457 S458 L459	T421-S455 WeakPolarHBondContact OG1-CA 3.31Å; T421-S455 PolarHBondContact OG1-N 3.03Å; S451-S455 PolarHBondContact O-N 3.43Å; S451-S455 VanDerWaalsContact O-N 3.12Å; S452-S455 WeakPolarHBondContact O-CB 3.43Å; S452-S455 PolarHBondContact O-N 2.95Å; S452-S455 VanDerWaalsContact O-N 3.1Å; V453-S455 VanDerWaalsContact C-N 3.26Å; V453-S455 PolarHBondContact O-N 3.21Å; S455-I457 PolarHBondContact O-N 2.93Å; S455-S458 WeakPolarHBondContact O-CB 3.21Å; S455-S458 PolarHBondContact O-N 3.22Å; S455-S458 VanDerWaalsContact O-N 3.14Å; S455-L459 PolarHBondContact O-N 3.45Å
456	F	97.6	Very high	98	Very high	103 Å²	103	46.2 Å²	46.2	45%	0.452	24%	0.242	S	C	.	.	H	α-helix	trans	-65.3	-36.2	173.3	-73.5	-69.3	0	0	0	112.9	L32 S452 V453 S458 L459 T460	L32-F456 HydrophobicContact CD2-CD1 4.19Å; L32-F456 HydrophobicContact CD2-CE1 4.32Å; S452-F456 WeakPolarHBondContact O-CD2 3.33Å; S452-F456 PolarHBondContact O-N 2.9Å; S452-F456 VanDerWaalsContact O-N 3.08Å; V453-F456 PolarHBondContact O-N 2.84Å; F456-S458 VanDerWaalsContact C-N 3.31Å; F456-S458 PolarHBondContact O-N 3.2Å; F456-L459 WeakPolarHBondContact O-CB 3.44Å; F456-L459 PolarHBondContact O-N 3.46Å; F456-T460 PolarHBondContact O-N 3.35Å
457	I	98.4	Very high	98	Very high	49 Å²	49	45.6 Å²	45.6	25%	0.251	23%	0.232	S	C	.	.	H	α-helix	trans	-62.1	-42.8	171.2	-66.3	166.3	0	0	0	109.9	I413 L420 V453 G454 S455 L459 T460 A461	I413-I457 HydrophobicContact CG2-CG2 3.87Å; I413-I457 WeakPolarHBondContact CG2-O 3.45Å; L420-I457 HydrophobicContact CD1-CD1 3.73Å; V453-I457 HydrophobicContact CG1-CD1 4.05Å; V453-I457 WeakPolarHBondContact O-CG1 3.38Å; V453-I457 PolarHBondContact O-N 3.41Å; G454-I457 PolarHBondContact O-N 2.72Å; S455-I457 PolarHBondContact O-N 2.93Å; I457-L459 VanDerWaalsContact C-N 3.29Å; I457-L459 PolarHBondContact O-N 3.22Å; I457-T460 WeakPolarHBondContact O-CB 3.47Å; I457-T460 PolarHBondContact O-N 3.21Å; I457-T460 PolarHBondContact O-OG1 2.66Å; I457-A461 PolarHBondContact O-N 2.9Å
458	S	97.4	Very high	98	Very high	16 Å²	16	41 Å²	41	11%	0.112	21%	0.214	C	C	.	.	H	α-helix	trans	-64.1	-34.1	178.8	-52.9	0	0	0	0	112.2	G417 V418 G454 S455 F456 T460 A461 V462	G417-S458 WeakPolarHBondContact CA-OG 3.38Å; V418-S458 PolarHBondContact N-OG 3.18Å; G454-S458 PolarHBondContact O-N 2.86Å; G454-S458 PolarHBondContact O-OG 3.13Å; S455-S458 WeakPolarHBondContact O-CB 3.21Å; S455-S458 PolarHBondContact O-N 3.22Å; S455-S458 VanDerWaalsContact O-N 3.14Å; F456-S458 VanDerWaalsContact C-N 3.31Å; F456-S458 PolarHBondContact O-N 3.2Å; S458-T460 VanDerWaalsContact C-N 3.31Å; S458-T460 PolarHBondContact O-N 3.37Å; S458-A461 WeakPolarHBondContact O-CB 3.32Å; S458-A461 PolarHBondContact O-N 3.02Å; S458-A461 VanDerWaalsContact O-N 3.15Å; S458-V462 PolarHBondContact O-N 3.08Å; S458-V462 VanDerWaalsContact O-N 3.1Å
459	L	97.4	Very high	98	Very high	54 Å²	54	43.7 Å²	43.7	28%	0.283	23%	0.228	S	C	.	.	H	α-helix	trans	-59.1	-41.3	170.6	171.8	60.8	0	0	0	111.9	L32 S455 F456 I457 A461 V462 M463	L32-L459 HydrophobicContact CD1-CB 4.17Å; L32-L459 HydrophobicContact CD1-CD1 3.84Å; L32-L459 HydrophobicContact CD1-CD2 3.72Å; L32-L459 HydrophobicContact CD1-CG 4.09Å; L32-L459 HydrophobicContact CD2-CB 4.16Å; L32-L459 HydrophobicContact CD2-CD2 4.36Å; S455-L459 PolarHBondContact O-N 3.45Å; F456-L459 WeakPolarHBondContact O-CB 3.44Å; F456-L459 PolarHBondContact O-N 3.46Å; I457-L459 VanDerWaalsContact C-N 3.29Å; I457-L459 PolarHBondContact O-N 3.22Å; L459-A461 PolarHBondContact O-N 3.08Å; L459-V462 PolarHBondContact O-N 3.3Å; L459-V462 VanDerWaalsContact O-N 3.09Å; L459-M463 HydrophobicContact CD1-CG 4.19Å; L459-M463 HydrophobicContact CD1-SD 4.48Å; L459-M463 WeakPolarHBondContact O-CG 3.41Å; L459-M463 PolarHBondContact O-N 3.32Å
460	T	98.1	Very high	98	Very high	75 Å²	75	48.4 Å²	48.4	46%	0.46	24%	0.242	S	C	.	.	H	α-helix	trans	-62	-33.5	177.1	69.7	0	0	0	0	112.2	I413 F456 I457 S458 M463 L464	I413-T460 WeakPolarHBondContact CG2-OG1 3.33Å; F456-T460 PolarHBondContact O-N 3.35Å; I457-T460 WeakPolarHBondContact O-CB 3.47Å; I457-T460 PolarHBondContact O-N 3.21Å; I457-T460 PolarHBondContact O-OG1 2.66Å; S458-T460 VanDerWaalsContact C-N 3.31Å; S458-T460 PolarHBondContact O-N 3.37Å; T460-M463 PolarHBondContact O-N 3.23Å; T460-L464 WeakPolarHBondContact O-CB 3.3Å; T460-L464 PolarHBondContact O-N 3.05Å
461	A	97.9	Very high	98	Very high	0 Å²	0	46.7 Å²	46.7	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-66.3	-43.4	172.3	0	0	0	0	0	111.9	H410 I413 M414 I457 S458 L459 M463 L464 M465	H410-A461 PolarHBondContact CD2-O 3.3Å; H410-A461 PolarHBondContact NE2-O 2.87Å; I413-A461 HydrophobicContact CB-CB 4.22Å; I413-A461 HydrophobicContact CG2-CB 3.82Å; M414-A461 HydrophobicContact CB-CB 3.84Å; M414-A461 HydrophobicContact CE-CB 3.72Å; M414-A461 HydrophobicContact SD-CB 4.22Å; I457-A461 PolarHBondContact O-N 2.9Å; S458-A461 WeakPolarHBondContact O-CB 3.32Å; S458-A461 PolarHBondContact O-N 3.02Å; S458-A461 VanDerWaalsContact O-N 3.15Å; L459-A461 PolarHBondContact O-N 3.08Å; A461-M463 VanDerWaalsContact C-N 3.32Å; A461-M463 PolarHBondContact O-N 3.37Å; A461-L464 WeakPolarHBondContact O-CB 3.42Å; A461-L464 PolarHBondContact O-N 3.45Å; A461-L464 VanDerWaalsContact O-N 3.15Å; A461-M465 PolarHBondContact O-N 3.17Å
462	V	97.4	Very high	97.9	Very high	31 Å²	31	46.7 Å²	46.7	19%	0.188	23%	0.232	C	C	.	.	H	α-helix	trans	-59.3	-43.6	175.6	175.5	0	0	0	0	111.4	T28 M414 S458 L459 L464 M465 I466	T28-V462 HydrophobicContact CG2-CG2 4.33Å; M414-V462 HydrophobicContact CE-CG2 4.2Å; S458-V462 PolarHBondContact O-N 3.08Å; S458-V462 VanDerWaalsContact O-N 3.1Å; L459-V462 PolarHBondContact O-N 3.3Å; L459-V462 VanDerWaalsContact O-N 3.09Å; V462-L464 VanDerWaalsContact C-N 3.34Å; V462-L464 PolarHBondContact O-N 3.43Å; V462-M465 WeakPolarHBondContact O-CB 3.26Å; V462-M465 PolarHBondContact O-N 3.34Å; V462-I466 PolarHBondContact O-N 2.94Å
463	M	98	Very high	97.9	Very high	112 Å²	112	51 Å²	51	55%	0.552	25%	0.25	S	S	*	.	H	α-helix	trans	-64.2	-39.6	175.9	-64.3	-54	-65.4	0	0	112.1	L459 T460 A461 M465 I466 F467	L459-M463 HydrophobicContact CD1-CG 4.19Å; L459-M463 HydrophobicContact CD1-SD 4.48Å; L459-M463 WeakPolarHBondContact O-CG 3.41Å; L459-M463 PolarHBondContact O-N 3.32Å; T460-M463 PolarHBondContact O-N 3.23Å; A461-M463 VanDerWaalsContact C-N 3.32Å; A461-M463 PolarHBondContact O-N 3.37Å; M463-M465 VanDerWaalsContact C-N 3.33Å; M463-M465 PolarHBondContact O-N 3.11Å; M463-I466 PolarHBondContact O-N 3.32Å; M463-I466 HydrophobicContact SD-CD1 4.35Å; M463-F467 PolarHBondContact O-N 3.2Å
464	L	98.3	Very high	97.8	Very high	28 Å²	28	50.6 Å²	50.6	15%	0.147	25%	0.254	C	S	.	.	H	α-helix	trans	-64.3	-36.8	175.3	-179.2	59.1	0	0	0	111.9	I409 H410 I413 T460 A461 V462 F467 M468	I409-L464 HydrophobicContact CB-CD2 4.33Å; I409-L464 HydrophobicContact CG2-CD2 3.8Å; H410-L464 HydrophobicContact CB-CD2 3.79Å; H410-L464 HydrophobicContact CB-CG 4.17Å; I413-L464 HydrophobicContact CD1-CD2 4.05Å; T460-L464 WeakPolarHBondContact O-CB 3.3Å; T460-L464 PolarHBondContact O-N 3.05Å; A461-L464 WeakPolarHBondContact O-CB 3.42Å; A461-L464 PolarHBondContact O-N 3.45Å; A461-L464 VanDerWaalsContact O-N 3.15Å; V462-L464 VanDerWaalsContact C-N 3.34Å; V462-L464 PolarHBondContact O-N 3.43Å; L464-F467 HydrophobicContact CD1-CD1 3.94Å; L464-F467 WeakPolarHBondContact O-CB 3.33Å; L464-F467 PolarHBondContact O-N 3.04Å; L464-M468 HydrophobicContact CD1-CG 4.41Å; L464-M468 HydrophobicContact CG-CG 4.46Å; L464-M468 HydrophobicContact CG-SD 4.35Å; L464-M468 WeakPolarHBondContact O-CB 3.41Å; L464-M468 VanDerWaalsContact O-CG 3.27Å; L464-M468 WeakPolarHBondContact O-CG 3.16Å; L464-M468 PolarHBondContact O-N 3.19Å
465	M	97.8	Very high	97.8	Very high	19 Å²	19	53 Å²	53	9%	0.094	27%	0.271	C	S	.	.	H	α-helix	trans	-60.7	-46.7	173.9	177.8	58.8	93.8	0	0	111.6	M387 F390 H410 A461 V462 M463 F467 M468 I469	M387-M465 HydrophobicContact SD-CE 3.21Å; M387-M465 WeakPolarHBondContact SD-CE 3.2Å; F390-M465 HydrophobicContact CD1-CE 3.92Å; F390-M465 HydrophobicContact CD1-SD 4.18Å; F390-M465 HydrophobicContact CE1-CE 4.23Å; F390-M465 HydrophobicContact CE1-SD 3.87Å; H410-M465 VanDerWaalsContact CE1-CE 3.48Å; H410-M465 WeakPolarHBondContact CE1-CE 3.37Å; A461-M465 PolarHBondContact O-N 3.17Å; V462-M465 WeakPolarHBondContact O-CB 3.26Å; V462-M465 PolarHBondContact O-N 3.34Å; M463-M465 VanDerWaalsContact C-N 3.33Å; M463-M465 PolarHBondContact O-N 3.11Å; M465-F467 VanDerWaalsContact C-N 3.29Å; M465-F467 PolarHBondContact O-N 3.07Å; M465-M468 PolarHBondContact O-N 3.24Å; M465-I469 HydrophobicContact CG-CD1 4.18Å; M465-I469 WeakPolarHBondContact O-CG1 3.41Å; M465-I469 PolarHBondContact O-N 3.35Å; M465-I469 HydrophobicContact SD-CD1 4.2Å; M465-I469 HydrophobicContact SD-CG1 4.25Å
466	I	97.8	Very high	97.6	Very high	83 Å²	83	58.6 Å²	58.6	43%	0.426	29%	0.294	S	S	.	.	H	α-helix	trans	-59.4	-44.5	177.2	-63.6	169	0	0	0	110.1	V462 M463 I469 W470	V462-I466 PolarHBondContact O-N 2.94Å; M463-I466 PolarHBondContact O-N 3.32Å; M463-I466 HydrophobicContact SD-CD1 4.35Å; I466-I469 PolarHBondContact O-N 3.31Å; I466-W470 PolarHBondContact O-N 3.19Å
467	F	98.4	Very high	97.4	Very high	78 Å²	78	57 Å²	57	34%	0.342	29%	0.285	S	S	.	.	H	α-helix	trans	-60	-45.6	175.2	171.1	-96.6	0	0	0	112.3	Y406 M463 L464 M465 I469 W470 E471	Y406-F467 HydrophobicContact CD2-CE1 4.1Å; Y406-F467 HydrophobicContact CE1-CE1 4.42Å; Y406-F467 AromaticContact CE2-CE1 3.94Å; Y406-F467 HydrophobicContact CE2-CE1 3.94Å; Y406-F467 HydrophobicContact CE2-CZ 4.5Å; Y406-F467 HydrophobicContact CG-CE1 4.45Å; M463-F467 PolarHBondContact O-N 3.2Å; L464-F467 HydrophobicContact CD1-CD1 3.94Å; L464-F467 WeakPolarHBondContact O-CB 3.33Å; L464-F467 PolarHBondContact O-N 3.04Å; M465-F467 VanDerWaalsContact C-N 3.29Å; M465-F467 PolarHBondContact O-N 3.07Å; F467-I469 VanDerWaalsContact C-N 3.32Å; F467-I469 PolarHBondContact O-N 3Å; F467-W470 AromaticContact CD2-CE3 3.85Å; F467-W470 HydrophobicContact CD2-CE3 3.85Å; F467-W470 HydrophobicContact CD2-CZ3 4.05Å; F467-W470 AromaticContact CE2-CE3 3.84Å; F467-W470 HydrophobicContact CE2-CE3 3.84Å; F467-W470 AromaticContact CE2-CZ3 3.58Å; F467-W470 HydrophobicContact CE2-CZ3 3.58Å; F467-W470 HydrophobicContact CZ-CZ3 4.39Å; F467-W470 PolarHBondContact O-N 2.83Å; F467-E471 HydrophobicContact CE1-CB 4.32Å; F467-E471 HydrophobicContact CE1-CG 4.38Å; F467-E471 HydrophobicContact CZ-CB 4.35Å; F467-E471 HydrophobicContact CZ-CG 4.26Å; F467-E471 WeakPolarHBondContact O-CB 3.47Å; F467-E471 PolarHBondContact O-N 3.4Å
468	M	98.3	Very high	97.1	Very high	1 Å²	1	62 Å²	62	1%	0.005	31%	0.305	C	S	.	.	H	α-helix	trans	-60.2	-41.5	179.3	-76.6	172.9	51.3	0	0	112.4	L402 A407 H410 L464 M465 E471 A472	L402-M468 HydrophobicContact CB-CE 4.32Å; L402-M468 HydrophobicContact CD1-CE 3.99Å; L402-M468 HydrophobicContact CD2-CB 4.45Å; L402-M468 HydrophobicContact CD2-CE 4.4Å; L402-M468 HydrophobicContact CG-CE 4.47Å; A407-M468 VanDerWaalsContact CA-CE 3.49Å; A407-M468 HydrophobicContact CB-CE 3.59Å; H410-M468 HydrophobicContact CB-SD 3.64Å; L464-M468 HydrophobicContact CD1-CG 4.41Å; L464-M468 HydrophobicContact CG-CG 4.46Å; L464-M468 HydrophobicContact CG-SD 4.35Å; L464-M468 WeakPolarHBondContact O-CB 3.41Å; L464-M468 VanDerWaalsContact O-CG 3.27Å; L464-M468 WeakPolarHBondContact O-CG 3.16Å; L464-M468 PolarHBondContact O-N 3.19Å; M465-M468 PolarHBondContact O-N 3.24Å; M468-E471 PolarHBondContact O-N 3.38Å; M468-A472 WeakPolarHBondContact O-CB 3.24Å; M468-A472 PolarHBondContact O-N 3.34Å
469	I	97.8	Very high	96.7	Very high	55 Å²	55	63 Å²	63	28%	0.282	31%	0.31	S	S	.	.	H	α-helix	trans	-63.9	-50.1	176.9	-65.9	170.6	0	0	0	109.6	F390 M465 I466 F467 E471 A472 F473	F390-I469 HydrophobicContact CE1-CD1 4.09Å; F390-I469 HydrophobicContact CE1-CG1 4.03Å; F390-I469 HydrophobicContact CZ-CD1 3.7Å; F390-I469 HydrophobicContact CZ-CG1 3.85Å; M465-I469 HydrophobicContact CG-CD1 4.18Å; M465-I469 WeakPolarHBondContact O-CG1 3.41Å; M465-I469 PolarHBondContact O-N 3.35Å; M465-I469 HydrophobicContact SD-CD1 4.2Å; M465-I469 HydrophobicContact SD-CG1 4.25Å; I466-I469 PolarHBondContact O-N 3.31Å; F467-I469 VanDerWaalsContact C-N 3.32Å; F467-I469 PolarHBondContact O-N 3Å; I469-E471 VanDerWaalsContact C-N 3.32Å; I469-E471 PolarHBondContact O-N 3.49Å; I469-A472 PolarHBondContact O-N 3.18Å; I469-F473 HydrophobicContact CG2-CD2 3.9Å; I469-F473 HydrophobicContact CG2-CE2 3.81Å; I469-F473 WeakPolarHBondContact O-CD2 3.29Å; I469-F473 PolarHBondContact O-N 3.23Å
470	W	97.9	Very high	95.9	Very high	160 Å²	160	68.7 Å²	68.7	61%	0.606	34%	0.34	S	S	*	.	H	α-helix	trans	-56.2	-46.7	176.6	168.6	81.7	0	0	0	111.9	I466 F467 A472 F473 A474	I466-W470 PolarHBondContact O-N 3.19Å; F467-W470 AromaticContact CD2-CE3 3.85Å; F467-W470 HydrophobicContact CD2-CE3 3.85Å; F467-W470 HydrophobicContact CD2-CZ3 4.05Å; F467-W470 AromaticContact CE2-CE3 3.84Å; F467-W470 HydrophobicContact CE2-CE3 3.84Å; F467-W470 AromaticContact CE2-CZ3 3.58Å; F467-W470 HydrophobicContact CE2-CZ3 3.58Å; F467-W470 HydrophobicContact CZ-CZ3 4.39Å; F467-W470 PolarHBondContact O-N 2.83Å; W470-A472 PolarHBondContact O-N 3.06Å; W470-F473 PolarHBondContact O-N 3.05Å; W470-A474 HydrophobicContact CZ2-CB 4.49Å; W470-A474 WeakPolarHBondContact O-CB 3.42Å; W470-A474 PolarHBondContact O-N 2.81Å
471	E	98	Very high	95	Very high	31 Å²	31	72.7 Å²	72.7	15%	0.145	36%	0.356	C	S	.	.	H	α-helix	trans	-63.5	-39.7	-178.1	-170.8	-74	144.7	0	0	111.6	F467 M468 I469 A474 S475 R477	F467-E471 HydrophobicContact CE1-CB 4.32Å; F467-E471 HydrophobicContact CE1-CG 4.38Å; F467-E471 HydrophobicContact CZ-CB 4.35Å; F467-E471 HydrophobicContact CZ-CG 4.26Å; F467-E471 WeakPolarHBondContact O-CB 3.47Å; F467-E471 PolarHBondContact O-N 3.4Å; M468-E471 PolarHBondContact O-N 3.38Å; I469-E471 VanDerWaalsContact C-N 3.32Å; I469-E471 PolarHBondContact O-N 3.49Å; E471-A474 PolarHBondContact O-N 2.93Å; E471-S475 VanDerWaalsContact O-CB 3.26Å; E471-S475 WeakPolarHBondContact O-CB 3.3Å; E471-S475 PolarHBondContact O-N 2.86Å; E471-S475 PolarHBondContact O-OG 3.02Å; E471-R477 IonicContact OE1-CZ 3.54Å; E471-R477 IonicContact OE1-NH1 2.67Å; E471-R477 PolarHBondContact OE1-NH1 2.95Å; E471-R477 IonicContact OE1-NH2 3.57Å; E471-R477 IonicContact OE2-CZ 3.42Å; E471-R477 IonicContact OE2-NH1 3.31Å; E471-R477 PolarHBondContact OE2-NH1 3.25Å; E471-R477 IonicContact OE2-NH2 2.67Å; E471-R477 PolarHBondContact OE2-NH2 3.01Å
472	A	97.3	Very high	94.2	Very high	0 Å²	0	74 Å²	74	0%	0	36%	0.363	C	S	.	.	H	α-helix	trans	-64	-41.3	175.4	0	0	0	0	0	112.6	F394 L402 M468 I469 W470 S475 K476	F394-A472 HydrophobicContact CE1-CB 3.76Å; F394-A472 HydrophobicContact CZ-CB 3.91Å; L402-A472 HydrophobicContact CD2-CB 3.94Å; M468-A472 WeakPolarHBondContact O-CB 3.24Å; M468-A472 PolarHBondContact O-N 3.34Å; I469-A472 PolarHBondContact O-N 3.18Å; W470-A472 PolarHBondContact O-N 3.06Å; A472-S475 PolarHBondContact O-OG 3.27Å; A472-K476 PolarHBondContact O-N 3.45Å
473	F	96.9	Very high	92.9	Very high	98 Å²	98	76.9 Å²	76.9	43%	0.43	38%	0.375	S	S	.	.	H	α-helix	trans	-73.7	-29.2	176.4	-76.8	-69.6	0	0	0	113.3	F394 Y400 I469 W470 K476	F394-F473 HydrophobicContact CE2-CE2 4.35Å; F394-F473 HydrophobicContact CZ-CE2 4.11Å; F394-F473 HydrophobicContact CZ-CZ 4.44Å; Y400-F473 AromaticContact CD2-CD1 3.66Å; Y400-F473 HydrophobicContact CD2-CD1 3.66Å; Y400-F473 AromaticContact CD2-CE1 3.73Å; Y400-F473 HydrophobicContact CD2-CE1 3.73Å; Y400-F473 AromaticContact CE2-CD1 3.64Å; Y400-F473 HydrophobicContact CE2-CD1 3.64Å; Y400-F473 AromaticContact CE2-CE1 3.84Å; Y400-F473 HydrophobicContact CE2-CE1 3.84Å; I469-F473 HydrophobicContact CG2-CD2 3.9Å; I469-F473 HydrophobicContact CG2-CE2 3.81Å; I469-F473 WeakPolarHBondContact O-CD2 3.29Å; I469-F473 PolarHBondContact O-N 3.23Å; W470-F473 PolarHBondContact O-N 3.05Å; F473-K476 VanDerWaalsContact O-CG 3.23Å; F473-K476 WeakPolarHBondContact O-CG 3.44Å
474	A	97.8	Very high	91.4	Very high	61 Å²	61	76.8 Å²	76.8	50%	0.504	37%	0.373	S	S	.	.	H	α-helix	trans	-73.9	-46.5	175.2	0	0	0	0	0	111.7	W470 E471	W470-A474 HydrophobicContact CZ2-CB 4.49Å; W470-A474 WeakPolarHBondContact O-CB 3.42Å; W470-A474 PolarHBondContact O-N 2.81Å; E471-A474 PolarHBondContact O-N 2.93Å
475	S	96.3	Very high	89.6	Confident	49 Å²	49	78 Å²	78	34%	0.343	38%	0.383	S	S	.	.	H	α-helix	trans	-74	-27.3	179.7	62.3	0	0	0	0	113.7	E471 A472 R477	E471-S475 VanDerWaalsContact O-CB 3.26Å; E471-S475 WeakPolarHBondContact O-CB 3.3Å; E471-S475 PolarHBondContact O-N 2.86Å; E471-S475 PolarHBondContact O-OG 3.02Å; A472-S475 PolarHBondContact O-OG 3.27Å; S475-R477 PolarHBondContact O-N 3.09Å; S475-R477 VanDerWaalsContact OG-CZ 3.29Å; S475-R477 PolarHBondContact OG-NH1 2.75Å; S475-R477 PolarHBondContact OG-NH2 2.97Å
476	K	94.8	Very high	87.9	Confident	128 Å²	128	81.9 Å²	81.9	56%	0.557	41%	0.412	S	S	*	.	T	Hydrogen-bonded Turn	trans	54.2	37.7	179.4	-59.7	-178.8	-179.3	175.3	0	113.3	Y400 A472 F473 K478	Y400-K476 HydrophobicContact CD1-CB 4.26Å; Y400-K476 HydrophobicContact CE1-CB 3.68Å; Y400-K476 HydrophobicContact CE1-CG 4.12Å; A472-K476 PolarHBondContact O-N 3.45Å; F473-K476 VanDerWaalsContact O-CG 3.23Å; F473-K476 WeakPolarHBondContact O-CG 3.44Å; K476-K478 PolarHBondContact O-N 3.33Å
477	R	93.4	Very high	86.7	Confident	70 Å²	70	81.7 Å²	81.7	26%	0.264	41%	0.41	S	S	.	.			trans	-65.8	100.2	176.3	-70.4	-175.1	-63.6	-86.8	-14.6	110.2	Y400 T401 E471 S475	Y400-R477 CarbonylContact C-O 3.47Å; Y400-R477 WeakPolarHBondContact CA-O 3.37Å; T401-R477 PolarHBondContact N-O 3.02Å; T401-R477 PolarHBondContact O-NE 2.88Å; T401-R477 PolarHBondContact O-NH2 3.24Å; T401-R477 WeakPolarHBondContact OG1-CB 3.27Å; T401-R477 PolarHBondContact OG1-O 2.75Å; E471-R477 IonicContact OE1-CZ 3.54Å; E471-R477 IonicContact OE1-NH1 2.67Å; E471-R477 PolarHBondContact OE1-NH1 2.95Å; E471-R477 IonicContact OE1-NH2 3.57Å; E471-R477 IonicContact OE2-CZ 3.42Å; E471-R477 IonicContact OE2-NH1 3.31Å; E471-R477 PolarHBondContact OE2-NH1 3.25Å; E471-R477 IonicContact OE2-NH2 2.67Å; E471-R477 PolarHBondContact OE2-NH2 3.01Å; S475-R477 PolarHBondContact O-N 3.09Å; S475-R477 VanDerWaalsContact OG-CZ 3.29Å; S475-R477 PolarHBondContact OG-NH1 2.75Å; S475-R477 PolarHBondContact OG-NH2 2.97Å
478	K	92.3	Very high	86.1	Confident	152 Å²	152	79.4 Å²	79.4	66%	0.661	40%	0.401	S	S	*	.	B	Isolated β-bridge	trans	-73.4	149.9	-178.1	-65.6	-174	179.2	-177.7	0	112	Y400 K476 L480	Y400-K478 HydrophobicContact CD1-CG 4.33Å; Y400-K478 HydrophobicContact CE1-CG 4.15Å; K476-K478 PolarHBondContact O-N 3.33Å; K478-L480 PolarHBondContact O-N 3.04Å
479	V	88.2	Confident	85.7	Confident	37 Å²	37	81 Å²	81	22%	0.224	41%	0.41	C	S	.	.			trans	-67.5	119.7	167.8	-175.5	0	0	0	0	109.1	P395 G399 T401 V482 C495	P395-V479 HydrophobicContact CB-CG2 3.43Å; P395-V479 VanDerWaalsContact CB-CG2 3.43Å; G399-V479 PolarHBondContact O-N 3.12Å; T401-V479 HydrophobicContact CG2-CG2 3.87Å; V479-V482 HydrophobicContact CG1-CG2 3.97Å; V479-C495 HydrophobicContact CB-CB 4.18Å; V479-C495 HydrophobicContact CG1-CB 4.47Å; V479-C495 HydrophobicContact CG2-CB 4.03Å
480	L	80.6	Confident	85.4	Confident	175 Å²	175	78.6 Å²	78.6	92%	0.916	40%	0.397	S	S	*	.			trans	-87	-41.1	177.1	-66.1	175.5	0	0	0	112	K478	K478-L480 PolarHBondContact O-N 3.04Å
481	M	79.3	Confident	85.1	Confident	159 Å²	159	71.7 Å²	71.7	78%	0.783	37%	0.371	S	S	*	.			trans	-151.9	137.6	179.6	-173.7	174.2	178.5	0	0	108.9
482	V	81.1	Confident	84.7	Confident	26 Å²	26	74.7 Å²	74.7	16%	0.158	39%	0.387	C	S	.	.			trans	-91.7	130.5	166.5	-177.1	0	0	0	0	107.6	V479 W491	V479-V482 HydrophobicContact CG1-CG2 3.97Å; V482-W491 HydrophobicContact CG1-CB 3.89Å; V482-W491 HydrophobicContact CG1-CD2 3.85Å; V482-W491 HydrophobicContact CG1-CE3 3.89Å; V482-W491 HydrophobicContact CG1-CG 3.84Å; V482-W491 HydrophobicContact CG2-CE3 3.95Å
483	E	70.8	Confident	84.3	Confident	93 Å²	93	77.8 Å²	77.8	44%	0.435	40%	0.402	S	S	.	.	S	Bend	trans	-75.9	133.4	176.3	-61.5	-178.6	150.3	0	0	109.7	Y257 K330	Y257-E483 WeakPolarHBondContact CE2-O 3.45Å; Y257-E483 PolarHBondContact OH-O 3.33Å; K330-E483 IonicContact NZ-OE1 3.07Å; K330-E483 PolarHBondContact NZ-OE1 2.87Å; K330-E483 IonicContact NZ-OE2 2.79Å; K330-E483 PolarHBondContact NZ-OE2 3.25Å
484	E	66.3	Low	84	Confident	110 Å²	110	74.7 Å²	74.7	51%	0.514	40%	0.397	S	S	.	.			trans	54.4	53.8	175.9	-59.1	-63.5	155.7	0	0	116.1	S486	E484-S486 PolarHBondContact O-N 2.92Å
485	P	60.7	Low	83.7	Confident	54 Å²	54	73.1 Å²	73.1	35%	0.351	38%	0.382	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.3	-15.9	-178.6	30.2	-35.2	0	0	0	113.4	M487 W491	P485-M487 VanDerWaalsContact C-N 3.27Å; P485-M487 PolarHBondContact O-N 3Å; P485-W491 HydrophobicContact CB-CB 4.37Å
486	S	62.4	Low	83.6	Confident	100 Å²	100	74.1 Å²	74.1	70%	0.699	39%	0.388	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.7	-18.8	-175.4	63	0	0	0	0	114	E484	E484-S486 PolarHBondContact O-N 2.92Å
487	M	72.5	Confident	83.6	Confident	78 Å²	78	68.6 Å²	68.6	38%	0.384	37%	0.365	S	S	.	.	S	Bend	trans	-97.1	-18.2	-177.7	-58.8	-174.7	-169.8	0	0	113.3	K262 P485	K262-M487 HydrophobicContact CB-SD 4.2Å; K262-M487 HydrophobicContact CD-CE 4.46Å; K262-M487 HydrophobicContact CG-CE 3.78Å; K262-M487 HydrophobicContact CG-SD 3.69Å; P485-M487 VanDerWaalsContact C-N 3.27Å; P485-M487 PolarHBondContact O-N 3Å
488	N	85.3	Confident	83.6	Confident	31 Å²	31	68.7 Å²	68.7	17%	0.166	38%	0.375	C	S	.	.			trans	-130.3	105.5	-172.3	-68.4	-59.9	0	0	0	109.7	E490 W491	N488-E490 PolarHBondContact O-N 2.83Å; N488-E490 VanDerWaalsContact O-N 3.15Å; N488-W491 PolarHBondContact O-N 2.84Å
489	L	89.5	Confident	83.5	Confident	35 Å²	35	67 Å²	67	18%	0.183	37%	0.365	C	S	.	.	G	3₁₀ helix	trans	-59.1	-28.9	-172.3	-69.2	177.6	0	0	0	113.4	L82 W491 L492 V506	L82-L489 WeakPolarHBondContact O-CB 3.24Å; L489-W491 PolarHBondContact O-N 3.31Å; L489-W491 VanDerWaalsContact O-N 3.16Å; L489-L492 VanDerWaalsContact O-CB 3.29Å; L489-L492 WeakPolarHBondContact O-CB 3.31Å; L489-L492 PolarHBondContact O-N 3.39Å; L489-L492 VanDerWaalsContact O-N 3.14Å; L489-V506 HydrophobicContact CD2-CG1 3.98Å
490	E	92.5	Very high	83.6	Confident	4 Å²	4	71.3 Å²	71.3	2%	0.019	38%	0.382	C	S	.	.	G	3₁₀ helix	trans	-64.2	-21.6	-178	70.8	-84.3	-161.7	0	0	113.7	L82 M83 L396 N488	L82-E490 HydrophobicContact CB-CB 3.89Å; L82-E490 HydrophobicContact CD1-CB 4.36Å; M83-E490 HydrophobicContact CE-CG 4.26Å; M83-E490 HydrophobicContact CG-CB 4.26Å; L396-E490 WeakPolarHBondContact CD1-O 3.39Å; L396-E490 HydrophobicContact CD2-CB 4.11Å; L396-E490 HydrophobicContact CD2-CG 4.13Å; N488-E490 PolarHBondContact O-N 2.83Å; N488-E490 VanDerWaalsContact O-N 3.15Å
491	W	91.9	Very high	84.1	Confident	14 Å²	14	63.1 Å²	63.1	5%	0.053	34%	0.34	C	S	.	.	G	3₁₀ helix	trans	-93.8	-5	179.3	-57.4	99.3	0	0	0	113.9	H392 W393 L396 V482 P485 N488 L489 H493 G494 C495	H392-W491 AromaticContact CE1-CZ2 3.88Å; H392-W491 AromaticContact NE2-CZ2 3.88Å; H392-W491 WeakPolarHBondContact O-CH2 3.42Å; W393-W491 AromaticContact CD1-CH2 3.95Å; W393-W491 AromaticContact CD1-CZ2 3.42Å; W393-W491 VanDerWaalsContact CD1-CZ2 3.42Å; W393-W491 HydrophobicContact CG-CZ2 4.39Å; W393-W491 AromaticContact NE1-CZ2 3.85Å; L396-W491 HydrophobicContact CB-CE3 4.2Å; L396-W491 HydrophobicContact CB-CH2 3.76Å; L396-W491 HydrophobicContact CB-CZ3 3.55Å; L396-W491 HydrophobicContact CD1-CE3 4.03Å; L396-W491 HydrophobicContact CD1-CZ3 4.23Å; L396-W491 HydrophobicContact CG-CZ3 4.4Å; V482-W491 HydrophobicContact CG1-CB 3.89Å; V482-W491 HydrophobicContact CG1-CD2 3.85Å; V482-W491 HydrophobicContact CG1-CE3 3.89Å; V482-W491 HydrophobicContact CG1-CG 3.84Å; V482-W491 HydrophobicContact CG2-CE3 3.95Å; P485-W491 HydrophobicContact CB-CB 4.37Å; N488-W491 PolarHBondContact O-N 2.84Å; L489-W491 PolarHBondContact O-N 3.31Å; L489-W491 VanDerWaalsContact O-N 3.16Å; W491-H493 VanDerWaalsContact C-N 3.35Å; W491-H493 PolarHBondContact O-N 3.08Å; W491-G494 PolarHBondContact O-N 3.22Å; W491-C495 VanDerWaalsContact CE3-SG 3.58Å
492	L	89.3	Confident	84.6	Confident	94 Å²	94	56.3 Å²	56.3	49%	0.492	31%	0.306	S	S	.	.	T	Hydrogen-bonded Turn	trans	-64.5	-37	-171.5	-174.7	66.1	0	0	0	113.1	L489 G494 F502	L489-L492 VanDerWaalsContact O-CB 3.29Å; L489-L492 WeakPolarHBondContact O-CB 3.31Å; L489-L492 PolarHBondContact O-N 3.39Å; L489-L492 VanDerWaalsContact O-N 3.14Å; L492-G494 PolarHBondContact O-N 3.1Å; L492-F502 HydrophobicContact CD2-CE1 4.3Å
493	H	89.4	Confident	84.8	Confident	66 Å²	66	63.2 Å²	63.2	31%	0.306	34%	0.336	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.4	20.1	-173.4	-69.4	-67.3	0	0	0	114	W491 P497 P498 T501 F502	W491-H493 VanDerWaalsContact C-N 3.35Å; W491-H493 PolarHBondContact O-N 3.08Å; H493-P497 HydrophobicContact CB-CB 3.97Å; H493-P497 WeakPolarHBondContact O-CA 3.33Å; H493-P498 WeakPolarHBondContact O-CD 3.32Å; H493-T501 HydrophobicContact CB-CG2 3.66Å; H493-F502 AromaticContact CD2-CE1 3.66Å; H493-F502 AromaticContact CD2-CE2 3.96Å; H493-F502 AromaticContact CD2-CZ 3.58Å; H493-F502 AromaticContact NE2-CD1 3.37Å; H493-F502 WeakPolarHBondContact NE2-CD1 3.29Å; H493-F502 AromaticContact NE2-CE1 3.28Å; H493-F502 VanDerWaalsContact NE2-CE1 3.28Å; H493-F502 WeakPolarHBondContact NE2-CE1 3.5Å; H493-F502 AromaticContact NE2-CG 3.92Å; H493-F502 AromaticContact NE2-CZ 3.71Å
494	G	89.1	Confident	85.3	Confident	32 Å²	32	66.7 Å²	66.7	33%	0.33	35%	0.353	S	S	.	.			trans	80.7	-175.1	177.3	0	0	0	0	0	114.3	W491 L492 P496	W491-G494 PolarHBondContact O-N 3.22Å; L492-G494 PolarHBondContact O-N 3.1Å; G494-P496 CarbonylContact O-C 3.28Å
495	C	92.9	Very high	85.8	Confident	28 Å²	28	66.3 Å²	66.3	19%	0.189	36%	0.36	C	S	.	.	S	Bend	trans	-133.9	105.3	-172.6	-67.3	0	0	0	0	110.5	P395 G399 V479 W491	P395-C495 WeakPolarHBondContact O-CB 3.3Å; G399-C495 WeakPolarHBondContact CA-O 3.08Å; V479-C495 HydrophobicContact CB-CB 4.18Å; V479-C495 HydrophobicContact CG1-CB 4.47Å; V479-C495 HydrophobicContact CG2-CB 4.03Å; W491-C495 VanDerWaalsContact CE3-SG 3.58Å
496	P	94.3	Very high	86.6	Confident	71 Å²	71	65 Å²	65	46%	0.461	35%	0.35	S	S	.	.	S	Bend	cis	-77.2	155.3	-4.6	34.7	-34.8	0	0	0	112.2	L396 G494	L396-P496 WeakPolarHBondContact O-CA 3.49Å; G494-P496 CarbonylContact O-C 3.28Å
497	P	93.6	Very high	87.1	Confident	12 Å²	12	69.4 Å²	69.4	8%	0.078	35%	0.353	C	S	.	.	P	Polyproline II helix	trans	-67.3	153.2	174.1	28	-33.9	0	0	0	111.6	K10 W78 L82 L396 H493 T501	K10-P497 HydrophobicContact CD-CG 4.37Å; W78-P497 HydrophobicContact CZ3-CG 4.14Å; L82-P497 HydrophobicContact CD1-CG 4.4Å; L396-P497 HydrophobicContact CD1-CG 4.4Å; L396-P497 WeakPolarHBondContact O-CD 3.49Å; H493-P497 HydrophobicContact CB-CB 3.97Å; H493-P497 WeakPolarHBondContact O-CA 3.33Å; P497-T501 HydrophobicContact CB-CG2 4.05Å
498	P	93.8	Very high	86.9	Confident	72 Å²	72	68.1 Å²	68.1	47%	0.468	35%	0.347	S	S	.	.	P	Polyproline II helix	trans	-57.6	161.6	171.8	-21.2	32	0	0	0	112	K10 H493 H500	K10-P498 PolarHBondContact NZ-O 3.47Å; H493-P498 WeakPolarHBondContact O-CD 3.32Å; P498-H500 VanDerWaalsContact C-N 3.34Å; P498-H500 PolarHBondContact O-N 3.43Å
499	Y	90.4	Very high	85.7	Confident	117 Å²	117	75.2 Å²	75.2	46%	0.459	38%	0.376	S	S	.	.	S	Bend	trans	-57.2	-48.2	179.1	-66.7	-65.7	0	0	0	112.1	R2 N8 K10	R2-Y499 VanDerWaalsContact CZ-CE1 3.44Å; R2-Y499 VanDerWaalsContact CZ-CZ 3.48Å; R2-Y499 PolarHBondContact NH1-OH 2.96Å; R2-Y499 PolarHBondContact NH2-OH 2.91Å; R2-Y499 VanDerWaalsContact NH2-OH 3.11Å; N8-Y499 PolarHBondContact ND2-O 3.01Å; K10-Y499 PolarHBondContact NZ-O 3.19Å
500	H	90.3	Very high	83.7	Confident	126 Å²	126	81.5 Å²	81.5	58%	0.583	42%	0.423	S	S	*	.	S	Bend	trans	-100.3	126.2	174.2	-59.2	-68.7	0	0	0	109.3	P498	P498-H500 VanDerWaalsContact C-N 3.34Å; P498-H500 PolarHBondContact O-N 3.43Å
501	T	91.4	Very high	83.2	Confident	4 Å²	4	85.4 Å²	85.4	3%	0.025	44%	0.443	C	S	.	.			trans	-127.6	159.8	176.9	40.7	0	0	0	0	108	K10 P87 H493 P497 E503	K10-T501 PolarHBondContact NZ-OG1 2.86Å; P87-T501 VanDerWaalsContact CA-O 3.26Å; P87-T501 WeakPolarHBondContact CA-O 3.26Å; P87-T501 WeakPolarHBondContact CB-O 3.49Å; H493-T501 HydrophobicContact CB-CG2 3.66Å; P497-T501 HydrophobicContact CB-CG2 4.05Å; T501-E503 PolarHBondContact O-N 3.24Å
502	F	90	Very high	82.8	Confident	15 Å²	15	89.2 Å²	89.2	7%	0.066	46%	0.464	C	S	.	.			trans	56	45.6	178.1	-46.4	-69.9	0	0	0	114.3	L82 G85 A86 L492 H493 E504 V506	L82-F502 HydrophobicContact CD2-CE2 3.92Å; G85-F502 WeakPolarHBondContact O-CB 3.39Å; A86-F502 WeakPolarHBondContact O-CD2 3.5Å; L492-F502 HydrophobicContact CD2-CE1 4.3Å; H493-F502 AromaticContact CD2-CE1 3.66Å; H493-F502 AromaticContact CD2-CE2 3.96Å; H493-F502 AromaticContact CD2-CZ 3.58Å; H493-F502 AromaticContact NE2-CD1 3.37Å; H493-F502 WeakPolarHBondContact NE2-CD1 3.29Å; H493-F502 AromaticContact NE2-CE1 3.28Å; H493-F502 VanDerWaalsContact NE2-CE1 3.28Å; H493-F502 WeakPolarHBondContact NE2-CE1 3.5Å; H493-F502 AromaticContact NE2-CG 3.92Å; H493-F502 AromaticContact NE2-CZ 3.71Å; F502-E504 CarbonylContact C-O 3.56Å; F502-E504 PolarHBondContact O-N 3.35Å; F502-V506 HydrophobicContact CD1-CG2 3.17Å; F502-V506 HydrophobicContact CE1-CG2 3.37Å; F502-V506 HydrophobicContact CG-CG2 4.2Å
503	E	84.5	Confident	82.4	Confident	172 Å²	172	88.9 Å²	88.9	80%	0.804	46%	0.462	S	S	*	.	S	Bend	trans	-60.2	-31.9	171.5	-66.1	-175.5	178.4	0	0	111.6	T501	T501-E503 PolarHBondContact O-N 3.24Å
504	E	81.1	Confident	82	Confident	166 Å²	166	90.2 Å²	90.2	78%	0.776	47%	0.472	S	S	*	.	S	Bend	trans	-107.6	142	167.2	-64.4	-175.5	173.7	0	0	110	F502 V506	F502-E504 CarbonylContact C-O 3.56Å; F502-E504 PolarHBondContact O-N 3.35Å; E504-V506 PolarHBondContact O-N 3.47Å
505	P	77.7	Confident	81.5	Confident	102 Å²	102	93.9 Å²	93.9	66%	0.662	48%	0.48	S	S	*	.			trans	-57.6	134.9	177.4	-24	33.3	0	0	0	112.1	Y507	P505-Y507 PolarHBondContact O-N 2.65Å
506	V	76.7	Confident	80.8	Confident	25 Å²	25	98.3 Å²	98.3	15%	0.152	50%	0.5	C	S	.	.			trans	-60.1	123.1	177	-177	0	0	0	0	110.1	P170 L489 F502 E504 M508	P170-V506 HydrophobicContact CG-CB 4.25Å; L489-V506 HydrophobicContact CD2-CG1 3.98Å; F502-V506 HydrophobicContact CD1-CG2 3.17Å; F502-V506 HydrophobicContact CE1-CG2 3.37Å; F502-V506 HydrophobicContact CG-CG2 4.2Å; E504-V506 PolarHBondContact O-N 3.47Å; V506-M508 HydrophobicContact CG1-CG 4.48Å; V506-M508 PolarHBondContact O-N 3.24Å
507	Y	72.4	Confident	79.8	Confident	194 Å²	194	100.2 Å²	100.2	76%	0.761	50%	0.503	S	S	*	.			trans	-74.1	115.9	170.3	-179.7	-100.3	0	0	0	110.1	P505 K509	P505-Y507 PolarHBondContact O-N 2.65Å; Y507-K509 HydrophobicContact CE1-CG 3.68Å
508	M	68.2	Low	78.7	Confident	51 Å²	51	107 Å²	107	25%	0.251	54%	0.535	S	S	.	.			trans	-103.7	123.1	173.8	-66.6	-97	-73.3	0	0	108.4	A172 M173 V506 S510	A172-M508 HydrophobicContact CB-CB 4.34Å; M173-M508 HydrophobicContact CB-CE 4.15Å; M173-M508 HydrophobicContact CE-CE 3.59Å; M173-M508 HydrophobicContact CE-SD 4.4Å; M173-M508 HydrophobicContact CG-CE 4.07Å; V506-M508 HydrophobicContact CG1-CG 4.48Å; V506-M508 PolarHBondContact O-N 3.24Å; M508-S510 PolarHBondContact O-N 2.82Å
509	K	60.2	Low	77.5	Confident	179 Å²	179	109.9 Å²	109.9	78%	0.778	54%	0.541	S	S	*	.			trans	-68.5	124.2	166.4	-80.2	-173.3	176.4	178.3	0	107.8	Y507	Y507-K509 HydrophobicContact CE1-CG 3.68Å
510	S	47	Very low	76.3	Confident	168 Å²	168	109.3 Å²	109.3	100%	1.175	55%	0.548	S	S	*	.			trans	-50.7	0	179.1	59.3	0	0	0	0	113.2	M508	M508-S510 PolarHBondContact O-N 2.82Å

Retrieved 510 of 510 residues in 120.7 ms (Link to these results)

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