A0A023T408_HUMAN Loading...

PVT1/EYA1 fusion protein isoform 2

AlphaFold DB , UniProt , Accession A0A023T408, Species HUMAN (Homo sapiens, Human), Gene n/a, Length 62 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M38.6Very low51.2Low242 Ų242133.5 Ų133.5100%1.19284%0.841SS**  0116.50-69.616173.600106.6
2S46.7Very low51.3Low122 Ų122133.3 Ų133.385%0.85383%0.83SS**  trans-81.5125.8179.1-179.70000108.7
3S43.8Very low51.5Low111 Ų111128.8 Ų128.878%0.77683%0.825SS**  trans-159.379.7168.2-66.60000108.9
4S57.5Low51.7Low118 Ų118126.2 Ų126.283%0.82581%0.812SS**  trans-91.2104.9155.7-74.90000106.4T6S4-T6 PolarHBondContact O-N 3.21Å
5E56.2Low52Low193 Ų193127.3 Ų127.390%0.90281%0.808SS**  trans-53.7119.9171.3-76.2176.679.200109.8A7E5-A7 PolarHBondContact O-N 3.25Å
6T57.4Low52.1Low130 Ų130126.8 Ų126.880%0.79880%0.797SS**  trans-75.9108165.148.80000107.4S4 S8S4-T6 PolarHBondContact O-N 3.21Å; T6-S8 PolarHBondContact O-N 3.3Å
7A54.1Low52.3Low90 Ų90128.1 Ų128.174%0.74480%0.797SS**  trans-60.6102.617500000109.8E5 T9E5-A7 PolarHBondContact O-N 3.25Å; A7-T9 PolarHBondContact O-N 3.36Å
8S52.3Low52.5Low117 Ų117131.9 Ų131.982%0.81880%0.801SS**  trans-64.494.6168.3-62.40000108.4T6 T10T6-S8 PolarHBondContact O-N 3.3Å; S8-T10 PolarHBondContact O-N 3.45Å
9T54.8Low53Low126 Ų126131.2 Ų131.277%0.77380%0.802SS**  trans-87.5109.1169-53.20000107A7 A11A7-T9 PolarHBondContact O-N 3.36Å; T9-A11 PolarHBondContact O-N 2.92Å; T9-A11 VanDerWaalsContact O-N 3.11Å
10T47.9Very low52.9Low113 Ų113127.4 Ų127.469%0.69379%0.79SS**  trans-50.2114.7175.5-49.50000109.4S8 D12S8-T10 PolarHBondContact O-N 3.45Å; T10-D12 HydrophobicContact CG2-CB 4.25Å; T10-D12 WeakPolarHBondContact CG2-OD1 3.5Å; T10-D12 PolarHBondContact O-N 2.99Å
11A54.2Low53Low106 Ų106126.1 Ų126.188%0.87679%0.786SS**  trans-95.374.9172.500000108.3T9T9-A11 PolarHBondContact O-N 2.92Å; T9-A11 VanDerWaalsContact O-N 3.11Å
12D52.1Low53.7Low132 Ų132119.4 Ų119.471%0.70677%0.769SS**  trans-115.8102.816867.7-41.4000110.6T10T10-D12 HydrophobicContact CG2-CB 4.25Å; T10-D12 WeakPolarHBondContact CG2-OD1 3.5Å; T10-D12 PolarHBondContact O-N 2.99Å
13G53.8Low54.1Low74 Ų74119.9 Ų119.976%0.76376%0.761SS**SBendtrans109.2110158.200000115.3
14S54.5Low54.6Low93 Ų93117.6 Ų117.665%0.6576%0.755SS**  trans77.282.4148.4-155.70000115.8N16S14-N16 PolarHBondContact O-N 3.07Å; S14-N16 PolarHBondContact OG-ND2 3.16Å
15L55.5Low54.7Low143 Ų143117 Ų11775%0.74975%0.751SS**  trans-59.974.6154.7-178.573.2000109.7F18L15-F18 HydrophobicContact CD1-CD2 3.59Å; L15-F18 HydrophobicContact CD1-CE2 3.66Å
16N54.4Low55Low118 Ų118112.5 Ų112.563%0.63174%0.741SS**  trans-145.677.3176.6-72.1-56.3000108.3S14S14-N16 PolarHBondContact O-N 3.07Å; S14-N16 PolarHBondContact OG-ND2 3.16Å
17N55.3Low55.5Low150 Ų150112 Ų11280%0.80274%0.743SS**  trans155.353.8154.8-79.9-41.4000111.9S19N17-S19 PolarHBondContact O-N 2.98Å; N17-S19 VanDerWaalsContact O-N 3.08Å
18F55.7Low56.2Low197 Ų197114.9 Ų114.986%0.86474%0.739SS**THydrogen-bonded Turntrans-80.241.2160.3-86-83.3000111.5L15L15-F18 HydrophobicContact CD1-CD2 3.59Å; L15-F18 HydrophobicContact CD1-CE2 3.66Å
19S61.8Low57.1Low117 Ų117114 Ų11482%0.81873%0.733SS**THydrogen-bonded Turntrans-127.723.4168.3-171.40000111.1N17N17-S19 PolarHBondContact O-N 2.98Å; N17-S19 VanDerWaalsContact O-N 3.08Å
20G51Low58Low55 Ų55113 Ų11357%0.56773%0.728SS**SBendtrans-103.999.6159.400000105.6A22G20-A22 VanDerWaalsContact C-N 3.28Å; G20-A22 PolarHBondContact O-N 3.39Å
21S55.8Low59.5Low101 Ų101118.1 Ų118.171%0.70674%0.735SS**  trans-41.5102.2161.7-152.50000106.5I23S21-I23 WeakPolarHBondContact OG-CD1 3.36Å; S21-I23 PolarHBondContact O-N 3.17Å; S21-I23 WeakPolarHBondContact O-CG1 3.22Å
22A53.3Low60.6Low102 Ų102119 Ų11984%0.84373%0.731SS**  trans-75.780.3173.100000103.7G20 G24G20-A22 VanDerWaalsContact C-N 3.28Å; G20-A22 PolarHBondContact O-N 3.39Å; A22-G24 PolarHBondContact O-N 2.92Å
23I54.3Low61.7Low131 Ų131118.9 Ų118.967%0.67274%0.736SS**  trans-5979.9175.1-58.1-62.1000106.5S21 S25S21-I23 WeakPolarHBondContact OG-CD1 3.36Å; S21-I23 PolarHBondContact O-N 3.17Å; S21-I23 WeakPolarHBondContact O-CG1 3.22Å; I23-S25 VanDerWaalsContact C-N 3.28Å; I23-S25 PolarHBondContact O-N 3.26Å
24G55.1Low62.9Low64 Ų64122 Ų12266%0.6673%0.73SS**  trans-70.199.4145.200000104.7A22 S26A22-G24 PolarHBondContact O-N 2.92Å; G24-S26 PolarHBondContact O-N 3.26Å
25S58.6Low64Low106 Ų106125.8 Ų125.874%0.74174%0.738SS**  trans-65.559.2163.658.20000109I23 S27I23-S25 VanDerWaalsContact C-N 3.28Å; I23-S25 PolarHBondContact O-N 3.26Å; S25-S27 VanDerWaalsContact C-N 3.33Å; S25-S27 PolarHBondContact O-N 2.9Å
26S62.7Low64.9Low97 Ų97127.6 Ų127.668%0.67874%0.74SS**  trans-69.6103.2164.4-173.20000104.4G24 F28G24-S26 PolarHBondContact O-N 3.26Å; S26-F28 PolarHBondContact O-N 3.15Å
27S68Low66Low121 Ų121126.6 Ų126.685%0.84674%0.742SS**  trans-68.247.6169.155.30000110.2S25 S29S25-S27 VanDerWaalsContact C-N 3.33Å; S25-S27 PolarHBondContact O-N 2.9Å; S27-S29 PolarHBondContact O-N 3.03Å; S27-S29 VanDerWaalsContact O-N 3.15Å
28F69.9Low67.2Low149 Ų149124.8 Ų124.865%0.65474%0.738SS**  trans-81.790.7175.6-173.6-100.9000107.1S26 P30S26-F28 PolarHBondContact O-N 3.15Å; F28-P30 HydrophobicContact CE1-CB 4.11Å; F28-P30 VanDerWaalsContact O-CD 3.26Å; F28-P30 WeakPolarHBondContact O-CD 3.35Å
29S71.4Confident68.1Low99 Ų99120.6 Ų120.669%0.69273%0.731SS**  trans-65.2115.2157.6-58.40000106.7S27 R31S27-S29 PolarHBondContact O-N 3.03Å; S27-S29 VanDerWaalsContact O-N 3.15Å; S29-R31 PolarHBondContact O-N 2.98Å
30P73.8Confident68.7Low104 Ų104123 Ų12368%0.67573%0.729SS**PPolyproline II helixtrans-58.5118.8174.123.9-31.2000107.3F28F28-P30 HydrophobicContact CE1-CB 4.11Å; F28-P30 VanDerWaalsContact O-CD 3.26Å; F28-P30 WeakPolarHBondContact O-CD 3.35Å
31R78.9Confident69.8Low222 Ų222127 Ų12784%0.83874%0.736SS**PPolyproline II helixtrans-61.6133.6173.3-68.9179179.4-103-0.1106.9S29 T33S29-R31 PolarHBondContact O-N 2.98Å; R31-T33 PolarHBondContact O-N 3.2Å
32P77Confident70.2Confident124 Ų124131 Ų13181%0.80574%0.737SS**PPolyproline II helixtrans-51.8130173-23.231.5000109.1H34P32-H34 PolarHBondContact O-N 3.01Å
33T75.5Confident70.9Confident129 Ų129129.6 Ų129.679%0.79172%0.72SS**PPolyproline II helixtrans-65.9119.1170.249.50000106.9R31 Q35R31-T33 PolarHBondContact O-N 3.2Å; T33-Q35 PolarHBondContact O-N 3.21Å
34H78.3Confident71.6Confident139 Ų139128.1 Ų128.164%0.64472%0.721SS**  trans-68.3104.4175.1-174.284.4000107.7P32 F36P32-H34 PolarHBondContact O-N 3.01Å; H34-F36 AromaticContact NE2-CZ 3.82Å; H34-F36 AromaticContact CD2-CD2 3.35Å; H34-F36 PolarHBondContact O-N 3.01Å; H34-F36 AromaticContact NE2-CE2 3.92Å; H34-F36 AromaticContact NE2-CE1 3.86Å; H34-F36 AromaticContact NE2-CD1 3.96Å; H34-F36 AromaticContact CD2-CZ 3.77Å; H34-F36 AromaticContact CD2-CG 3.72Å; H34-F36 WeakPolarHBondContact CD2-CE2 3.21Å; H34-F36 AromaticContact CD2-CE2 3.36Å; H34-F36 WeakPolarHBondContact CD2-CD2 3.26Å
35Q78.8Confident72.3Confident174 Ų174131.8 Ų131.881%0.81373%0.726SS**  trans-68.699.1168.5-96.3-171.6-56.700108T33 S37T33-Q35 PolarHBondContact O-N 3.21Å; Q35-S37 PolarHBondContact O-N 3.15Å
36F74.1Confident72.5Confident180 Ų180135.5 Ų135.579%0.78972%0.723SS**  trans-66.9103.1165.1-94.1-75.1000108.2H34H34-F36 AromaticContact NE2-CZ 3.82Å; H34-F36 AromaticContact CD2-CD2 3.35Å; H34-F36 PolarHBondContact O-N 3.01Å; H34-F36 AromaticContact NE2-CE2 3.92Å; H34-F36 AromaticContact NE2-CE1 3.86Å; H34-F36 AromaticContact NE2-CD1 3.96Å; H34-F36 AromaticContact CD2-CZ 3.77Å; H34-F36 AromaticContact CD2-CG 3.72Å; H34-F36 WeakPolarHBondContact CD2-CE2 3.21Å; H34-F36 AromaticContact CD2-CE2 3.36Å; H34-F36 WeakPolarHBondContact CD2-CD2 3.26Å
37S76.9Confident72.7Confident98 Ų98135.6 Ų135.669%0.68572%0.721SS**PPolyproline II helixtrans-68.9129.4161.6-31.20000107.1Q35Q35-S37 PolarHBondContact O-N 3.15Å
38P80.6Confident72.5Confident111 Ų111140 Ų14072%0.72172%0.721SS**PPolyproline II helixtrans-58.8135.6173.322.6-30.2000108.9Q40P38-Q40 PolarHBondContact O-N 2.71Å; P38-Q40 VanDerWaalsContact O-N 3.15Å
39P75.1Confident72.3Confident110 Ų110138.2 Ų138.271%0.71473%0.725SS**PPolyproline II helixtrans-59.5123.6176.622.4-30.3000108.5I41P39-I41 VanDerWaalsContact C-N 3.32Å; P39-I41 WeakPolarHBondContact O-CG1 3.39Å; P39-I41 PolarHBondContact O-N 3.04Å
40Q73.7Confident71.8Confident167 Ų167140.7 Ų140.778%0.7873%0.725SS**  trans-70.195.5172.7-75.9-150.731.400108.6P38 Y42P38-Q40 PolarHBondContact O-N 2.71Å; P38-Q40 VanDerWaalsContact O-N 3.15Å; Q40-Y42 PolarHBondContact O-N 2.76Å
41I73.5Confident71.4Confident139 Ų139143.6 Ų143.671%0.71373%0.733SS**  trans-71-11-175.9-11.7174.4000112.5P39P39-I41 VanDerWaalsContact C-N 3.32Å; P39-I41 WeakPolarHBondContact O-CG1 3.39Å; P39-I41 PolarHBondContact O-N 3.04Å
42Y65.7Low70.8Confident184 Ų184140 Ų14072%0.72273%0.729SS**SBendtrans-132129.3179-60.2-68.7000110.4Q40 S44Q40-Y42 PolarHBondContact O-N 2.76Å; Y42-S44 PolarHBondContact O-N 2.79Å
43P67.9Low70.2Confident74 Ų74139.7 Ų139.748%0.48173%0.728SS.*  trans-65.4121.1170-22.636.7000109.5N45 R46P43-N45 PolarHBondContact O-N 3.24Å; P43-R46 HydrophobicContact CB-CG 4.2Å; P43-R46 PolarHBondContact O-N 2.73Å
44S68.8Low70Confident100 Ų100139.9 Ų139.970%0.69973%0.729SS**THydrogen-bonded Turntrans-57.3-15.6179.552.40000114.6Y42Y42-S44 PolarHBondContact O-N 2.79Å
45N68.1Low69.5Low141 Ų141138.8 Ų138.875%0.75473%0.734SS**THydrogen-bonded Turntrans-111.812.9-170.2-73.866.6000114.4P43 P47P43-N45 PolarHBondContact O-N 3.24Å; N45-P47 WeakPolarHBondContact O-CD 3.17Å
46R64.5Low69.1Low183 Ų183135.7 Ų135.769%0.69173%0.732SS**SBendtrans-85.4123.3169.9-70.4179.5-166.2-143.56.8108.7P43 Y48P43-R46 HydrophobicContact CB-CG 4.2Å; P43-R46 PolarHBondContact O-N 2.73Å; R46-Y48 PolarHBondContact O-N 2.75Å
47P67.2Low69.1Low99 Ų99132.8 Ų132.864%0.64373%0.734SS**PPolyproline II helixtrans-51.5125.9166.9-17.827000108N45N45-P47 WeakPolarHBondContact O-CD 3.17Å
48Y62Low68.8Low213 Ų213136.7 Ų136.784%0.83574%0.741SS**PPolyproline II helixtrans-47.6144.1169.6-85.5-93000109.1R46 H50R46-Y48 PolarHBondContact O-N 2.75Å; Y48-H50 PolarHBondContact O-N 3.08Å
49P67.1Low68.5Low113 Ų113138 Ų13873%0.73475%0.747SS**PPolyproline II helixtrans-52119.8-173.422.5-32.9000108.8I51P49-I51 PolarHBondContact O-N 3.32Å
50H60.2Low68.1Low151 Ų151141.4 Ų141.470%0.69976%0.756SS**  trans-50.4109-178.7-53.3-87.3000107.5Y48 L52Y48-H50 PolarHBondContact O-N 3.08Å; H50-L52 PolarHBondContact O-N 3.25Å
51I64.6Low67.8Low165 Ų165138 Ų13885%0.84676%0.756SS**  trans-52.4114.3165-51.4171.6000103.2P49P49-I51 PolarHBondContact O-N 3.32Å
52L67.3Low67.4Low145 Ų145139.6 Ų139.676%0.75979%0.79SS**  trans-48.8135.5-179.1-86.170.5000106.8H50 T54H50-L52 PolarHBondContact O-N 3.25Å; L52-T54 PolarHBondContact O-N 2.94Å
53P63.4Low67.5Low119 Ų119137.4 Ų137.477%0.77379%0.794SS**  trans-44.4125.6-179.6-2631.3000108.8
54T71.6Confident67.5Low133 Ų133140.7 Ų140.782%0.81681%0.81SS**PPolyproline II helixtrans-47.8120.4176.8-10.80000106.8L52 S56L52-T54 PolarHBondContact O-N 2.94Å; T54-S56 PolarHBondContact O-N 2.96Å
55P68.8Low67.4Low116 Ų116143 Ų14375%0.75382%0.816SS**PPolyproline II helixtrans-56.6132.2-179.622-31.5000107.8S57P55-S57 PolarHBondContact O-N 3.11Å; P55-S57 VanDerWaalsContact O-N 3.16Å
56S69.8Low67.4Low109 Ų109143.1 Ų143.176%0.76282%0.82SS**PPolyproline II helixtrans-55.3123.5-178.352.20000109.4T54 Q58T54-S56 PolarHBondContact O-N 2.96Å; S56-Q58 PolarHBondContact O-N 3.5Å
57S73.4Confident67.5Low119 Ų119140.6 Ų140.683%0.83283%0.828SS**PPolyproline II helixtrans-61.2123.5177-154.40000108.9P55 T59P55-S57 PolarHBondContact O-N 3.11Å; P55-S57 VanDerWaalsContact O-N 3.16Å; S57-T59 PolarHBondContact O-N 2.8Å
58Q72.4Confident67.6Low180 Ų180143.4 Ų143.484%0.84184%0.841SS**PPolyproline II helixtrans-75117.4176.9-66-178.122.200108.7S56 M60S56-Q58 PolarHBondContact O-N 3.5Å; Q58-M60 PolarHBondContact O-N 3.44Å
59T72.8Confident68Low138 Ų138138.4 Ų138.485%0.84784%0.841SS**  trans-72.3113.9170.8-59.90000108.9S57 A61S57-T59 PolarHBondContact O-N 2.8Å; T59-A61 PolarHBondContact O-N 2.82Å
60M67.1Low68Low182 Ų182140.4 Ų140.490%0.89785%0.849SS**  trans-73.9117.4166.8-175177.8-8700108Q58Q58-M60 PolarHBondContact O-N 3.44Å
61A67.8Low68.7Low94 Ų94139.5 Ų139.578%0.77786%0.862SS**  trans-74135.9172.900000109.7T59T59-A61 PolarHBondContact O-N 2.82Å
62A65.3Low69.1Low174 Ų174137.2 Ų137.2100%1.43886%0.863SS**  trans-95.30172.800000110.8

Retrieved 62 of 62 residues in 28.2 ms (Link to these results)