A0A024CDU6_MOUSE Loading...

Survival motor neuron protein isoform n

AlphaFold DB , UniProt , Accession A0A024CDU6, Species MOUSE (Mus musculus, Mouse), Gene SMN2, Length 63 aa.

						>A0A024CDU6_MOUSE|A0A024CDU6|SMN2
NTAASLQQNENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKEMLA
					

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	N	42.8	Very low	56.5	Low	215 Å²	215	142.2 Å²	142.2	100%	1.15	80%	0.801	S	S	*	*				0	82.4	0	-43.7	-36.3	0	0	0	107.4
2	T	43.8	Very low	57	Low	143 Å²	143	146 Å²	146	88%	0.877	81%	0.807	S	S	*	*			trans	-80.5	137.4	-170.8	-55.1	0	0	0	0	109.7	A4	T2-A4 PolarHBondContact O-N 2.89Å
3	A	52.5	Low	57.9	Low	89 Å²	89	142.2 Å²	142.2	74%	0.736	80%	0.797	S	S	*	*			trans	-46.2	129.7	-178.9	0	0	0	0	0	112.5	S5	A3-S5 VanDerWaalsContact C-N 3.28Å; A3-S5 PolarHBondContact O-N 2.68Å
4	A	60.6	Low	58.8	Low	106 Å²	106	144.8 Å²	144.8	88%	0.876	80%	0.8	S	S	*	*			trans	-68	89.8	167.6	0	0	0	0	0	108.2	T2 L6	T2-A4 PolarHBondContact O-N 2.89Å; A4-L6 PolarHBondContact O-N 3.35Å
5	S	59.8	Low	59.5	Low	99 Å²	99	143.8 Å²	143.8	69%	0.692	80%	0.799	S	S	*	*			trans	-76.9	113.2	175.7	-158.6	0	0	0	0	108.9	A3 Q7	A3-S5 VanDerWaalsContact C-N 3.28Å; A3-S5 PolarHBondContact O-N 2.68Å; S5-Q7 PolarHBondContact O-N 2.85Å
6	L	57.8	Low	60	Low	140 Å²	140	142 Å²	142	73%	0.733	80%	0.799	S	S	*	*			trans	19.9	93.7	140.3	-73.8	83	0	0	0	115.1	A4	A4-L6 PolarHBondContact O-N 3.35Å
7	Q	60.7	Low	60.4	Low	186 Å²	186	140.9 Å²	140.9	87%	0.869	80%	0.797	S	S	*	*			trans	-142.4	80.5	133.9	-65.9	-165	-8.9	0	0	106	S5 N9	S5-Q7 PolarHBondContact O-N 2.85Å; Q7-N9 PolarHBondContact O-N 2.61Å
8	Q	58.8	Low	60.9	Low	181 Å²	181	140.3 Å²	140.3	85%	0.846	79%	0.791	S	S	*	*			trans	-59	92.6	158.8	-68.9	180	-97.5	0	0	105.1	E10	Q8-E10 WeakPolarHBondContact O-CG 3.12Å; Q8-E10 PolarHBondContact O-N 2.92Å
9	N	55.4	Low	61.4	Low	98 Å²	98	141.8 Å²	141.8	52%	0.524	79%	0.791	S	S	.	*			trans	-59.4	108.7	-173.1	168.9	40.6	0	0	0	108.7	Q7 N11	Q7-N9 PolarHBondContact O-N 2.61Å; N9-N11 VanDerWaalsContact CG-CG 3.41Å; N9-N11 VanDerWaalsContact CG-ND2 3.26Å; N9-N11 PolarHBondContact ND2-ND2 2.74Å; N9-N11 PolarHBondContact ND2-OD1 3.29Å; N9-N11 PolarHBondContact O-N 3.33Å; N9-N11 PolarHBondContact OD1-ND2 3.07Å
10	E	63.9	Low	61.8	Low	199 Å²	199	139.2 Å²	139.2	93%	0.93	78%	0.783	S	S	*	*	T	Hydrogen-bonded Turn	trans	-67.4	28.1	-174.6	-62.8	167.1	90.3	0	0	113.1	Q8	Q8-E10 WeakPolarHBondContact O-CG 3.12Å; Q8-E10 PolarHBondContact O-N 2.92Å
11	N	65.6	Low	62	Low	108 Å²	108	140.2 Å²	140.2	58%	0.578	78%	0.781	S	S	*	*	T	Hydrogen-bonded Turn	trans	-124.4	22	-172.2	82	26.2	0	0	0	115.6	N9 S13	N9-N11 VanDerWaalsContact CG-CG 3.41Å; N9-N11 VanDerWaalsContact CG-ND2 3.26Å; N9-N11 PolarHBondContact ND2-ND2 2.74Å; N9-N11 PolarHBondContact ND2-OD1 3.29Å; N9-N11 PolarHBondContact O-N 3.33Å; N9-N11 PolarHBondContact OD1-ND2 3.07Å; N11-S13 PolarHBondContact O-N 2.81Å
12	E	62.8	Low	63	Low	188 Å²	188	134.9 Å²	134.9	88%	0.879	75%	0.753	S	S	*	*	S	Bend	trans	-72.3	73.2	164.2	-54.1	-147.7	123.4	0	0	109.7	Q14	E12-Q14 PolarHBondContact O-N 2.69Å
13	S	68.1	Low	64	Low	97 Å²	97	132.9 Å²	132.9	68%	0.678	75%	0.745	S	S	*	*			trans	33.9	88.6	150.7	-170.8	0	0	0	0	114	N11 V15	N11-S13 PolarHBondContact O-N 2.81Å; S13-V15 PolarHBondContact O-N 2.79Å
14	Q	70.3	Confident	64.7	Low	178 Å²	178	138.2 Å²	138.2	83%	0.832	75%	0.746	S	S	*	*			trans	-41.3	111.1	160.1	-73	-76.4	-67.3	0	0	109.1	E12 S16	E12-Q14 PolarHBondContact O-N 2.69Å; Q14-S16 VanDerWaalsContact C-N 3.33Å; Q14-S16 PolarHBondContact O-N 3.47Å
15	V	69.3	Low	65	Low	130 Å²	130	138 Å²	138	79%	0.788	74%	0.738	S	S	*	*			trans	-63.8	94.8	171.8	-81.3	0	0	0	0	107.9	S13 T17	S13-V15 PolarHBondContact O-N 2.79Å; V15-T17 PolarHBondContact O-N 2.81Å
16	S	68	Low	65.3	Low	115 Å²	115	139.2 Å²	139.2	80%	0.804	74%	0.744	S	S	*	*			trans	-77	80.4	171.6	-65.4	0	0	0	0	108.3	Q14 D18	Q14-S16 VanDerWaalsContact C-N 3.33Å; Q14-S16 PolarHBondContact O-N 3.47Å; S16-D18 VanDerWaalsContact C-N 3.33Å
17	T	66.4	Low	65.4	Low	123 Å²	123	135.7 Å²	135.7	76%	0.755	74%	0.741	S	S	*	*			trans	-95.7	74.3	158.4	-50	0	0	0	0	106.9	V15 E19	V15-T17 PolarHBondContact O-N 2.81Å; T17-E19 PolarHBondContact O-N 3.48Å
18	D	69.8	Low	65.8	Low	130 Å²	130	132.9 Å²	132.9	70%	0.695	73%	0.732	S	S	*	*			trans	-89.6	95.9	159.9	-175.2	-118.2	0	0	0	107	S16 S20	S16-D18 VanDerWaalsContact C-N 3.33Å; D18-S20 PolarHBondContact O-N 3.04Å
19	E	70	Confident	66	Low	169 Å²	169	132.9 Å²	132.9	79%	0.79	73%	0.729	S	S	*	*			trans	-58.6	66	162.3	-94.9	-102.1	105.9	0	0	109.4	T17 E21	T17-E19 PolarHBondContact O-N 3.48Å; E19-E21 PolarHBondContact O-N 2.94Å
20	S	70.5	Confident	66.2	Low	90 Å²	90	132 Å²	132	63%	0.629	73%	0.731	S	S	*	*			trans	-71.8	83.1	161.9	52.2	0	0	0	0	106.8	D18 N22	D18-S20 PolarHBondContact O-N 3.04Å; S20-N22 PolarHBondContact O-N 2.81Å
21	E	65.8	Low	66.2	Low	160 Å²	160	130.6 Å²	130.6	75%	0.748	73%	0.729	S	S	*	*			trans	-54.7	85.4	145.2	-171.9	-175.4	94.3	0	0	105.1	E19 S23	E19-E21 PolarHBondContact O-N 2.94Å; E21-S23 PolarHBondContact O-N 2.9Å; E21-S23 PolarHBondContact O-OG 3.47Å
22	N	63.3	Low	66	Low	103 Å²	103	133 Å²	133	55%	0.551	74%	0.742	S	S	*	*			trans	-48.8	100.4	162.4	163.3	83.5	0	0	0	103.3	S20 R24	S20-N22 PolarHBondContact O-N 2.81Å; N22-R24 WeakPolarHBondContact ND2-CB 3.2Å; N22-R24 PolarHBondContact O-N 3.48Å
23	S	64	Low	65.9	Low	101 Å²	101	130.2 Å²	130.2	71%	0.706	73%	0.732	S	S	*	*			trans	-68	72.2	-173.2	-6.7	0	0	0	0	105.8	E21 S25	E21-S23 PolarHBondContact O-N 2.9Å; E21-S23 PolarHBondContact O-OG 3.47Å; S23-S25 PolarHBondContact O-N 2.92Å
24	R	67.3	Low	65.8	Low	201 Å²	201	134.2 Å²	134.2	76%	0.758	74%	0.737	S	S	*	*			trans	-79.1	80.8	179.4	-146	165.4	-163.5	116.5	4.7	103.4	N22 P26	N22-R24 WeakPolarHBondContact ND2-CB 3.2Å; N22-R24 PolarHBondContact O-N 3.48Å; R24-P26 WeakPolarHBondContact O-CD 3.4Å
25	S	68.1	Low	65.6	Low	102 Å²	102	130.3 Å²	130.3	71%	0.713	73%	0.727	S	S	*	*			trans	-46	117.4	155.3	-80	0	0	0	0	105.3	S23 G27	S23-S25 PolarHBondContact O-N 2.92Å; S25-G27 PolarHBondContact O-N 3.47Å
26	P	65.1	Low	65.5	Low	125 Å²	125	134.2 Å²	134.2	81%	0.812	73%	0.734	S	S	*	*			trans	-62.5	94.6	175.7	-20	33.1	0	0	0	105.2	R24 N28	R24-P26 WeakPolarHBondContact O-CD 3.4Å; P26-N28 PolarHBondContact O-N 2.72Å
27	G	59.4	Low	65.5	Low	65 Å²	65	132.1 Å²	132.1	67%	0.67	72%	0.719	S	S	*	*			trans	-53.2	112.3	177	0	0	0	0	0	105.6	S25	S25-G27 PolarHBondContact O-N 3.47Å
28	N	69.4	Low	65.4	Low	127 Å²	127	129 Å²	129	68%	0.679	71%	0.706	S	S	*	*			trans	-50.3	150.4	176.7	52.9	61.4	0	0	0	109.9	P26	P26-N28 PolarHBondContact O-N 2.72Å
29	K	64.1	Low	65.8	Low	181 Å²	181	126.5 Å²	126.5	79%	0.787	70%	0.696	S	S	*	*			trans	93	118.7	177.8	-48	163.6	-144.8	-159.9	0	112
30	S	58.7	Low	65.8	Low	80 Å²	80	129.2 Å²	129.2	56%	0.559	70%	0.7	S	S	*	*			cis	-161.4	138.9	15.6	37.7	0	0	0	0	107.4	N32	S30-N32 PolarHBondContact O-N 2.83Å
31	D	64.4	Low	65.7	Low	169 Å²	169	130.7 Å²	130.7	90%	0.904	70%	0.7	S	S	*	*	S	Bend	trans	-38.2	130.2	163.6	-80.4	-93.1	0	0	0	110.8
32	N	60.4	Low	66.2	Low	159 Å²	159	127.1 Å²	127.1	85%	0.85	69%	0.693	S	S	*	*			trans	86.7	39.4	178.8	-140.1	-76.2	0	0	0	118.2	S30	S30-N32 PolarHBondContact O-N 2.83Å
33	I	61.7	Low	67	Low	129 Å²	129	131 Å²	131	66%	0.662	71%	0.705	S	S	*	*			trans	-102.4	86.7	153.8	-52.2	171.3	0	0	0	106.8	P35	I33-P35 WeakPolarHBondContact O-CD 3.49Å
34	K	66.7	Low	68	Low	181 Å²	181	131.7 Å²	131.7	79%	0.787	70%	0.701	S	S	*	*			trans	-56.7	115	166.2	-177.2	169.9	174	-177.4	0	106.2	K36	K34-K36 PolarHBondContact O-N 2.96Å
35	P	65.4	Low	69	Low	96 Å²	96	127.2 Å²	127.2	62%	0.623	70%	0.698	S	S	*	*			trans	-60.8	112.2	-177.4	22.8	-31.2	0	0	0	107.9	I33 S37	I33-P35 WeakPolarHBondContact O-CD 3.49Å; P35-S37 PolarHBondContact O-N 2.73Å; P35-S37 VanDerWaalsContact O-N 3.07Å
36	K	66.8	Low	69.9	Low	213 Å²	213	127.8 Å²	127.8	93%	0.926	70%	0.699	S	S	*	*			trans	-73.8	23.4	169.1	-74.5	178.2	170.5	177	0	111.2	K34 A38	K34-K36 PolarHBondContact O-N 2.96Å; K36-A38 PolarHBondContact O-N 3.01Å
37	S	67.4	Low	71	Confident	71 Å²	71	127.3 Å²	127.3	50%	0.497	70%	0.696	S	S	.	*	P	Polyproline II helix	trans	-68.4	121.2	165.1	57.2	0	0	0	0	106.3	P35	P35-S37 PolarHBondContact O-N 2.73Å; P35-S37 VanDerWaalsContact O-N 3.07Å
38	A	66.1	Low	72.4	Confident	57 Å²	57	129.4 Å²	129.4	47%	0.471	70%	0.698	S	S	.	*	P	Polyproline II helix	trans	-47.3	130.5	159.6	0	0	0	0	0	106.8	K36 W40	K36-A38 PolarHBondContact O-N 3.01Å; A38-W40 PolarHBondContact O-N 2.76Å
39	P	77.6	Confident	73.4	Confident	77 Å²	77	129.2 Å²	129.2	50%	0.5	70%	0.703	S	S	.	*	P	Polyproline II helix	trans	-54.2	125.8	172.3	22.2	-29.1	0	0	0	105.1	N41 S42	P39-N41 PolarHBondContact O-N 2.81Å; P39-S42 WeakPolarHBondContact O-CB 3.46Å; P39-S42 PolarHBondContact O-N 2.74Å
40	W	69.9	Low	74.6	Confident	227 Å²	227	128.5 Å²	128.5	86%	0.86	71%	0.705	S	S	*	*	G	3₁₀ helix	trans	-53.8	-16.6	-178.4	-75.6	58.1	0	0	0	111.9	A38 S42	A38-W40 PolarHBondContact O-N 2.76Å; W40-S42 VanDerWaalsContact C-N 3.35Å; W40-S42 PolarHBondContact O-N 3.18Å
41	N	69	Low	75.8	Confident	120 Å²	120	129.5 Å²	129.5	64%	0.642	71%	0.709	S	S	*	*	G	3₁₀ helix	trans	-74.3	-9.1	173.9	-54.6	-42.7	0	0	0	115.5	P39 F43 L44	P39-N41 PolarHBondContact O-N 2.81Å; N41-F43 VanDerWaalsContact C-N 3.32Å; N41-F43 PolarHBondContact O-N 2.96Å; N41-L44 HydrophobicContact CB-CD1 4.49Å; N41-L44 PolarHBondContact O-N 3.32Å
42	S	75.4	Confident	76.5	Confident	86 Å²	86	123.8 Å²	123.8	60%	0.601	69%	0.69	S	S	*	*	G	3₁₀ helix	trans	-76.2	-15.6	-179.8	-96.8	0	0	0	0	114.2	P39 W40	P39-S42 WeakPolarHBondContact O-CB 3.46Å; P39-S42 PolarHBondContact O-N 2.74Å; W40-S42 VanDerWaalsContact C-N 3.35Å; W40-S42 PolarHBondContact O-N 3.18Å
43	F	79.9	Confident	77.3	Confident	183 Å²	183	122.5 Å²	122.5	80%	0.803	69%	0.691	S	S	*	*	G	3₁₀ helix	trans	-91.1	-0.5	175.6	-67.3	-78.2	0	0	0	113.3	N41	N41-F43 VanDerWaalsContact C-N 3.32Å; N41-F43 PolarHBondContact O-N 2.96Å
44	L	85.6	Confident	77.6	Confident	116 Å²	116	127.3 Å²	127.3	61%	0.607	70%	0.701	S	S	*	*	S	Bend	trans	-79.6	139.1	177.1	-59.7	178.7	0	0	0	109.6	N41	N41-L44 HydrophobicContact CB-CD1 4.49Å; N41-L44 PolarHBondContact O-N 3.32Å
45	P	88	Confident	77.5	Confident	108 Å²	108	124.2 Å²	124.2	70%	0.701	69%	0.692	S	S	*	*	P	Polyproline II helix	trans	-59.3	150.3	170.9	26.9	-33.7	0	0	0	109.8
46	P	86.8	Confident	77.7	Confident	114 Å²	114	121.6 Å²	121.6	74%	0.74	68%	0.682	S	S	*	*	P	Polyproline II helix	trans	-56.5	145.7	175.8	25.1	-33.7	0	0	0	110
47	P	87.4	Confident	77.8	Confident	114 Å²	114	118.6 Å²	118.6	74%	0.74	69%	0.685	S	S	*	*	P	Polyproline II helix	trans	-58	144.3	177	25.1	-33.1	0	0	0	109.7
48	P	90.4	Very high	77.5	Confident	110 Å²	110	118.1 Å²	118.1	71%	0.714	69%	0.691	S	S	*	*	P	Polyproline II helix	trans	-59.5	149.9	176.1	26.4	-33.8	0	0	0	109.9	M50	P48-M50 PolarHBondContact O-N 3.32Å
49	P	90.4	Very high	77.2	Confident	122 Å²	122	122 Å²	122	79%	0.792	70%	0.697	S	S	*	*	P	Polyproline II helix	trans	-56.4	127.4	172.5	24.5	-32.3	0	0	0	108.4
50	M	88.4	Confident	76.4	Confident	166 Å²	166	126.5 Å²	126.5	82%	0.818	71%	0.711	S	S	*	*	P	Polyproline II helix	trans	-57.1	134.1	174.7	-161.5	68.1	63.3	0	0	107.8	P48 G52	P48-M50 PolarHBondContact O-N 3.32Å; M50-G52 PolarHBondContact O-N 2.77Å
51	P	83.7	Confident	75.7	Confident	101 Å²	101	123.3 Å²	123.3	66%	0.656	71%	0.708	S	S	*	*	P	Polyproline II helix	trans	-51.9	117.7	166.6	-21.4	31.7	0	0	0	106.9
52	G	79	Confident	75.1	Confident	49 Å²	49	125.8 Å²	125.8	51%	0.505	72%	0.72	S	S	.	*	P	Polyproline II helix	trans	-53.2	157.4	179.1	0	0	0	0	0	109.8	M50 R54	M50-G52 PolarHBondContact O-N 2.77Å; G52-R54 PolarHBondContact O-N 2.92Å
53	P	78.8	Confident	73.5	Confident	132 Å²	132	128.9 Å²	128.9	86%	0.857	75%	0.751	S	S	*	*			trans	-46.2	115	173.5	-22.7	30.9	0	0	0	107.3	L55	P53-L55 PolarHBondContact O-N 2.85Å
54	R	67.5	Low	73.2	Confident	231 Å²	231	126.2 Å²	126.2	87%	0.872	75%	0.749	S	S	*	*			trans	-60.6	103.4	175.2	-70.7	-162.1	-156	-95.7	3.8	104	G52 G56	G52-R54 PolarHBondContact O-N 2.92Å; R54-G56 PolarHBondContact O-N 3.45Å
55	L	64.5	Low	72.6	Confident	115 Å²	115	126.7 Å²	126.7	60%	0.602	76%	0.756	S	S	*	*			trans	-68.1	88.2	167	-169.8	80.7	0	0	0	104.7	P53 K59	P53-L55 PolarHBondContact O-N 2.85Å; L55-K59 HydrophobicContact CD1-CD 3.67Å; L55-K59 HydrophobicContact CD1-CG 3.84Å; L55-K59 HydrophobicContact CD2-CD 4.04Å; L55-K59 HydrophobicContact CD2-CG 3.94Å; L55-K59 HydrophobicContact CG-CD 4.21Å; L55-K59 HydrophobicContact CG-CG 3.98Å
56	G	69	Low	71.7	Confident	41 Å²	41	127.7 Å²	127.7	42%	0.423	76%	0.759	S	S	.	*			trans	-53.3	150.4	177.4	0	0	0	0	0	109	R54 G58	R54-G56 PolarHBondContact O-N 3.45Å; G56-G58 PolarHBondContact O-N 2.97Å
57	P	68.8	Low	70.8	Confident	150 Å²	150	128.5 Å²	128.5	97%	0.974	76%	0.76	S	S	*	*	S	Bend	trans	-58.9	89.8	165.7	-14.5	27.9	0	0	0	108.1
58	G	61.4	Low	69.8	Low	61 Å²	61	129.4 Å²	129.4	63%	0.629	76%	0.761	S	S	*	*			trans	-179.8	11.3	-171.2	0	0	0	0	0	114	G56	G56-G58 PolarHBondContact O-N 2.97Å
59	K	60	Low	68.4	Low	138 Å²	138	130.7 Å²	130.7	60%	0.6	77%	0.765	S	S	*	*			trans	-117.9	68.8	159.7	67.3	155.7	-160	-113.4	0	110.5	L55 M61	L55-K59 HydrophobicContact CD1-CD 3.67Å; L55-K59 HydrophobicContact CD1-CG 3.84Å; L55-K59 HydrophobicContact CD2-CD 4.04Å; L55-K59 HydrophobicContact CD2-CG 3.94Å; L55-K59 HydrophobicContact CG-CD 4.21Å; L55-K59 HydrophobicContact CG-CG 3.98Å; K59-M61 PolarHBondContact O-N 3.15Å
60	E	61.3	Low	66.9	Low	172 Å²	172	131.4 Å²	131.4	80%	0.804	76%	0.763	S	S	*	*			trans	-58.1	95.8	139.5	48.7	-123	-177.7	0	0	107.4	L62	E60-L62 PolarHBondContact O-N 2.73Å
61	M	55.2	Low	65.2	Low	160 Å²	160	128.7 Å²	128.7	79%	0.788	76%	0.758	S	S	*	*			trans	-73.4	90.2	166.4	-169.3	175	77.4	0	0	106.2	K59 A63	K59-M61 PolarHBondContact O-N 3.15Å; M61-A63 PolarHBondContact O-N 3.01Å; M61-A63 VanDerWaalsContact O-N 3.15Å
62	L	54.8	Low	63.7	Low	172 Å²	172	131 Å²	131	90%	0.901	77%	0.767	S	S	*	*			trans	-71.5	94.8	165.3	-158.6	150.2	0	0	0	106.7	E60	E60-L62 PolarHBondContact O-N 2.73Å
63	A	43.6	Very low	62.3	Low	151 Å²	151	138.5 Å²	138.5	100%	1.248	79%	0.791	S	S	*	*			trans	-165.5	0	158.8	0	0	0	0	0	109.6	M61	M61-A63 PolarHBondContact O-N 3.01Å; M61-A63 VanDerWaalsContact O-N 3.15Å

Retrieved 63 of 63 residues in 37.6 ms (Link to these results)

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