A0A024RCQ1_HUMAN Loading...

Epithelial discoidin domain-containing receptor 1

AlphaFold DB , UniProt , Accession A0A024RCQ1, Species HUMAN (Homo sapiens, Human), Gene n/a, Length 876 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M42.1Very low38.1Very low239 Ų239112.5 Ų112.5100%1.17765%0.645SS**  0132.90-72.3157.3169.900107.4
2G37.8Very low38Very low41 Ų41113 Ų11342%0.42364%0.643SS.*  trans-84.9164.4-175.800000113.5E4 A5G2-E4 PolarHBondContact O-N 2.77Å; G2-A5 WeakPolarHBondContact O-CB 3.07Å; G2-A5 PolarHBondContact O-N 2.88Å; G2-A5 VanDerWaalsContact O-N 3.08Å
3P39.6Very low37.3Very low113 Ų113113.2 Ų113.273%0.73464%0.64SS**Hα-helixtrans-61.8-28.9-178.124.5-33.9000113.7A5 L6 S7P3-A5 PolarHBondContact O-N 3.02Å; P3-L6 PolarHBondContact O-N 3.34Å; P3-L6 VanDerWaalsContact O-N 3.1Å; P3-S7 PolarHBondContact O-N 3.29Å
4E37.4Very low37.3Very low160 Ų160114.6 Ų114.675%0.74864%0.644SS**Hα-helixtrans-62.1-27175.3-60.2-174.6146.400113.3G2 S7 S8G2-E4 PolarHBondContact O-N 2.77Å; E4-S7 PolarHBondContact O-N 3.26Å; E4-S8 WeakPolarHBondContact O-CB 3.47Å; E4-S8 PolarHBondContact O-N 3.26Å; E4-S8 PolarHBondContact O-OG 3.18Å
5A37.1Very low37.4Very low53 Ų53112.6 Ų112.644%0.43864%0.635SS.*Hα-helixtrans-69.4-36.817500000111.5G2 P3 L9G2-A5 WeakPolarHBondContact O-CB 3.07Å; G2-A5 PolarHBondContact O-N 2.88Å; G2-A5 VanDerWaalsContact O-N 3.08Å; P3-A5 PolarHBondContact O-N 3.02Å; A5-L9 WeakPolarHBondContact O-CB 3.29Å; A5-L9 PolarHBondContact O-N 2.8Å
6L37.6Very low37Very low129 Ų129110.5 Ų110.568%0.67564%0.636SS**Hα-helixtrans-68.4-41.9172.9-94.585.2000111.4P3 S8 L9 L10P3-L6 PolarHBondContact O-N 3.34Å; P3-L6 VanDerWaalsContact O-N 3.1Å; L6-S8 VanDerWaalsContact C-N 3.33Å; L6-S8 PolarHBondContact O-N 2.74Å; L6-L9 PolarHBondContact O-N 2.89Å; L6-L10 WeakPolarHBondContact O-CB 3.18Å; L6-L10 PolarHBondContact O-N 3.36Å
7S37.9Very low36.6Very low84 Ų84107.2 Ų107.259%0.58762%0.622SS**Hα-helixtrans-59.4-45.2177.3-166.20000111.5P3 E4 L10 L11P3-S7 PolarHBondContact O-N 3.29Å; E4-S7 PolarHBondContact O-N 3.26Å; S7-L10 PolarHBondContact O-N 3.22Å; S7-L11 PolarHBondContact O-N 3.1Å; S7-L11 VanDerWaalsContact O-N 3.08Å
8S38.6Very low36.5Very low69 Ų69105.1 Ų105.148%0.48363%0.626SS.*Hα-helixtrans-63.4-40.5175-58.90000112.9E4 L6 L11 L12E4-S8 WeakPolarHBondContact O-CB 3.47Å; E4-S8 PolarHBondContact O-N 3.26Å; E4-S8 PolarHBondContact O-OG 3.18Å; L6-S8 VanDerWaalsContact C-N 3.33Å; L6-S8 PolarHBondContact O-N 2.74Å; S8-L11 PolarHBondContact O-N 2.97Å; S8-L12 WeakPolarHBondContact O-CD1 3.48Å; S8-L12 PolarHBondContact O-N 3.21Å
9L35.1Very low36.4Very low111 Ų111107.9 Ų107.958%0.58164%0.638SS**Hα-helixtrans-69.3-37.5179.5-155.875.3000112.1A5 L6 L11 L12 L13A5-L9 WeakPolarHBondContact O-CB 3.29Å; A5-L9 PolarHBondContact O-N 2.8Å; L6-L9 PolarHBondContact O-N 2.89Å; L9-L11 VanDerWaalsContact C-N 3.31Å; L9-L12 PolarHBondContact O-N 3.14Å; L9-L13 WeakPolarHBondContact O-CB 3.38Å; L9-L13 WeakPolarHBondContact O-CG 3.47Å; L9-L13 PolarHBondContact O-N 3.32Å
10L36.3Very low36.6Very low117 Ų117105 Ų10561%0.61363%0.627SS**Hα-helixtrans-65.5-36.6174.7-145.377000111.4L6 S7 L13 L14L6-L10 WeakPolarHBondContact O-CB 3.18Å; L6-L10 PolarHBondContact O-N 3.36Å; S7-L10 PolarHBondContact O-N 3.22Å; L10-L13 PolarHBondContact O-N 2.89Å; L10-L14 PolarHBondContact O-N 2.88Å
11L39.8Very low37.4Very low121 Ų121106 Ų10663%0.63463%0.629SS**Hα-helixtrans-67.7-40.5175.7-146.475.1000112.1S7 S8 L9 L14 V15S7-L11 PolarHBondContact O-N 3.1Å; S7-L11 VanDerWaalsContact O-N 3.08Å; S8-L11 PolarHBondContact O-N 2.97Å; L9-L11 VanDerWaalsContact C-N 3.31Å; L11-L14 PolarHBondContact O-N 2.86Å; L11-V15 PolarHBondContact O-N 2.87Å
12L36.3Very low38.1Very low119 Ų11995.2 Ų95.262%0.62358%0.576SS**Hα-helixtrans-65.8-40.8172.4-95.581.4000112.2S8 L9 L14 V15 A16S8-L12 WeakPolarHBondContact O-CD1 3.48Å; S8-L12 PolarHBondContact O-N 3.21Å; L9-L12 PolarHBondContact O-N 3.14Å; L12-L14 PolarHBondContact O-N 3.05Å; L12-V15 PolarHBondContact O-N 2.86Å; L12-A16 VanDerWaalsContact O-CB 3.24Å; L12-A16 WeakPolarHBondContact O-CB 3.14Å; L12-A16 PolarHBondContact O-N 3.46Å
13L29.6Very low38.9Very low116 Ų116102.2 Ų102.261%0.60759%0.594SS**Hα-helixtrans-62.6-26.4178.6-82.1161.9000113.3L9 L10L9-L13 WeakPolarHBondContact O-CB 3.38Å; L9-L13 WeakPolarHBondContact O-CG 3.47Å; L9-L13 PolarHBondContact O-N 3.32Å; L10-L13 PolarHBondContact O-N 2.89Å
14L37.1Very low39.5Very low132 Ų13297.9 Ų97.969%0.69157%0.571SS**Hα-helixtrans-77.7-23.3172.3-78.5163.5000113.9L10 L11 L12L10-L14 PolarHBondContact O-N 2.88Å; L11-L14 PolarHBondContact O-N 2.86Å; L12-L14 PolarHBondContact O-N 3.05Å
15V39.3Very low40.8Very low85 Ų8592.5 Ų92.552%0.51555%0.545SS..Hα-helixtrans-92.4-26177.5178.40000112.3L11 L12 R332L11-V15 PolarHBondContact O-N 2.87Å; L12-V15 PolarHBondContact O-N 2.86Å; V15-R332 PolarHBondContact O-NH2 2.77Å
16A30Very low42.3Very low79 Ų7991.4 Ų91.465%0.65353%0.531SS*.  trans-90.414.1-174.700000114.9L12 G18L12-A16 VanDerWaalsContact O-CB 3.24Å; L12-A16 WeakPolarHBondContact O-CB 3.14Å; L12-A16 PolarHBondContact O-N 3.46Å; A16-G18 PolarHBondContact O-N 2.83Å
17S31.4Very low44Very low55 Ų5587.8 Ų87.839%0.38551%0.512SS..  trans-73.9108.4162.547.10000109.5
18G33.5Very low45.5Very low68 Ų6885.1 Ų85.170%0.70149%0.493SS*.THydrogen-bonded Turntrans-66.4148.2161.400000109.8A16 A20A16-G18 PolarHBondContact O-N 2.83Å; G18-A20 VanDerWaalsContact C-N 3.27Å; G18-A20 PolarHBondContact O-N 3.07Å
19D35.4Very low47Very low159 Ų15985.2 Ų85.285%0.8550%0.498SS*.THydrogen-bonded Turntrans41.552.8179.9-57.7-9.6000113.6D21D19-D21 PolarHBondContact O-N 2.77Å
20A40.9Very low49.1Very low50 Ų5086.7 Ų86.741%0.41350%0.499SS..  trans-68.777.6166.800000109.6G18 M22G18-A20 VanDerWaalsContact C-N 3.27Å; G18-A20 PolarHBondContact O-N 3.07Å; A20-M22 PolarHBondContact O-N 2.75Å
21D51.5Low51.4Low127 Ų12781.3 Ų81.368%0.67947%0.472SS*.  trans-45.6137.1177.3-167.79000110.5D19 K23D19-D21 PolarHBondContact O-N 2.77Å; D21-K23 VanDerWaalsContact O-CG 3.31Å; D21-K23 WeakPolarHBondContact O-CG 3.25Å; D21-K23 PolarHBondContact O-N 2.69Å
22M57.8Low53.8Low12 Ų1277.4 Ų77.46%0.05945%0.448CS..  trans-77.794-157.2-170.8163.9148.400109.2A20 G24 H25 Q284 H286 A333 E361 S363A20-M22 PolarHBondContact O-N 2.75Å; M22-G24 PolarHBondContact O-N 3.01Å; M22-H25 HydrophobicContact CB-CB 3.62Å; M22-H25 HydrophobicContact CE-CB 4.17Å; M22-H25 HydrophobicContact CG-CB 3.6Å; M22-H25 WeakPolarHBondContact O-CB 3.29Å; M22-H25 PolarHBondContact O-N 2.9Å; M22-H25 HydrophobicContact SD-CB 4.16Å; M22-Q284 HydrophobicContact CE-CB 4.32Å; M22-Q284 HydrophobicContact CE-CG 4.38Å; M22-Q284 WeakPolarHBondContact CE-O 3.43Å; M22-Q284 HydrophobicContact CG-CB 4.4Å; M22-Q284 VanDerWaalsContact CG-CD 3.49Å; M22-Q284 HydrophobicContact CG-CG 3.83Å; M22-Q284 HydrophobicContact SD-CG 4.35Å; M22-H286 HydrophobicContact SD-CB 4.19Å; M22-A333 HydrophobicContact CB-CB 4.33Å; M22-A333 HydrophobicContact CG-CB 4.02Å; M22-A333 HydrophobicContact SD-CB 3.81Å; M22-E361 HydrophobicContact CE-CB 4.3Å; M22-E361 HydrophobicContact CE-CG 3.53Å; M22-S363 VanDerWaalsContact CE-OG 3.29Å; M22-S363 WeakPolarHBondContact CE-OG 3.5Å
23K55.2Low56.5Low187 Ų18776.9 Ų76.981%0.81344%0.439SS*.THydrogen-bonded Turntrans-63.9-15.4-159.7-62.3-172.2179.1177.80116.3D21 Q284 I365D21-K23 VanDerWaalsContact O-CG 3.31Å; D21-K23 WeakPolarHBondContact O-CG 3.25Å; D21-K23 PolarHBondContact O-N 2.69Å; K23-Q284 VanDerWaalsContact N-OE1 3.17Å; K23-I365 HydrophobicContact CB-CD1 4.18Å
24G52Low59.5Low23 Ų2371.6 Ų71.624%0.23741%0.412CS..THydrogen-bonded Turntrans-103.2-7.117200000114.8M22 S363M22-G24 PolarHBondContact O-N 3.01Å; G24-S363 WeakPolarHBondContact O-CB 3.41Å
25H63.9Low62.2Low46 Ų4666.4 Ų66.421%0.21339%0.385CS..  trans-77.2154.6-178.9174.767.3000111.2M22 G234 E361M22-H25 HydrophobicContact CB-CB 3.62Å; M22-H25 HydrophobicContact CE-CB 4.17Å; M22-H25 HydrophobicContact CG-CB 3.6Å; M22-H25 WeakPolarHBondContact O-CB 3.29Å; M22-H25 PolarHBondContact O-N 2.9Å; M22-H25 HydrophobicContact SD-CB 4.16Å; H25-G234 PolarHBondContact CE1-O 2.7Å; H25-G234 VanDerWaalsContact CE1-O 3.22Å; H25-E361 IonicContact CE1-OE1 3.48Å; H25-E361 IonicContact ND1-OE1 2.76Å; H25-E361 PolarHBondContact ND1-OE1 3.45Å; H25-E361 VanDerWaalsContact ND1-OE1 3.1Å
26F69.8Low64.7Low31 Ų3162.3 Ų62.314%0.13636%0.36CS..  trans-116.6139.8175.559.5-82.5000108.7P28 L96 W187 D233 G234 E361F26-P28 HydrophobicContact CD2-CG 4.4Å; F26-P28 HydrophobicContact CE2-CG 4.28Å; F26-P28 WeakPolarHBondContact O-CD 3.12Å; F26-L96 HydrophobicContact CD2-CD2 3.52Å; F26-L96 HydrophobicContact CE2-CD1 3.93Å; F26-L96 HydrophobicContact CE2-CD2 3.42Å; F26-L96 VanDerWaalsContact CE2-CD2 3.42Å; F26-L96 HydrophobicContact CE2-CG 4.27Å; F26-L96 HydrophobicContact CZ-CD1 4.35Å; F26-W187 HydrophobicContact CD1-CH2 4.3Å; F26-W187 AromaticContact CD1-CZ3 3.82Å; F26-W187 HydrophobicContact CD1-CZ3 3.82Å; F26-W187 AromaticContact CE1-CH2 3.52Å; F26-W187 HydrophobicContact CE1-CH2 3.52Å; F26-W187 AromaticContact CE1-CZ3 3.35Å; F26-W187 HydrophobicContact CE1-CZ3 3.35Å; F26-W187 HydrophobicContact CE2-CZ3 4.18Å; F26-W187 HydrophobicContact CG-CZ3 4.44Å; F26-W187 AromaticContact CZ-CH2 3.84Å; F26-W187 HydrophobicContact CZ-CH2 3.84Å; F26-W187 AromaticContact CZ-CZ3 3.54Å; F26-W187 HydrophobicContact CZ-CZ3 3.54Å; F26-D233 WeakPolarHBondContact CE2-O 3.32Å; F26-D233 VanDerWaalsContact CZ-C 3.48Å; F26-G234 VanDerWaalsContact CE2-CA 3.42Å; F26-G234 VanDerWaalsContact CZ-CA 3.42Å; F26-E361 WeakPolarHBondContact CE1-OE1 3.32Å
27D71.7Confident67.9Low52 Ų5258.6 Ų58.628%0.27833%0.329SS..  trans-97.9113.8177.2174.8-21.9000108.9A29 K30 C31D27-A29 PolarHBondContact O-N 3.47Å; D27-A29 VanDerWaalsContact OD1-CA 3.31Å; D27-A29 WeakPolarHBondContact OD1-CA 3.38Å; D27-A29 VanDerWaalsContact OD1-CB 3.22Å; D27-A29 WeakPolarHBondContact OD1-CB 3.38Å; D27-A29 PolarHBondContact OD1-N 2.81Å; D27-K30 HydrophobicContact CB-CB 4.08Å; D27-K30 HydrophobicContact CB-CD 3.97Å; D27-K30 HydrophobicContact CB-CG 4.04Å; D27-K30 PolarHBondContact O-N 2.79Å; D27-K30 PolarHBondContact OD1-N 3.44Å; D27-K30 WeakPolarHBondContact OD2-CD 3.45Å; D27-K30 VanDerWaalsContact OD2-CE 3.25Å; D27-K30 WeakPolarHBondContact OD2-CE 3.4Å; D27-K30 WeakPolarHBondContact OD2-CG 3.35Å; D27-K30 IonicContact OD2-NZ 3.25Å; D27-K30 PolarHBondContact OD2-NZ 3.22Å; D27-C31 VanDerWaalsContact O-CB 3.3Å; D27-C31 WeakPolarHBondContact O-CB 3.41Å; D27-C31 PolarHBondContact O-N 3.45Å
28P69.9Low70.8Confident29 Ų2959.9 Ų59.919%0.18833%0.329CS..THydrogen-bonded Turntrans-59.8-24.6178.6-25.836.1000114.5F26 R32 G234F26-P28 HydrophobicContact CD2-CG 4.4Å; F26-P28 HydrophobicContact CE2-CG 4.28Å; F26-P28 WeakPolarHBondContact O-CD 3.12Å; P28-R32 WeakPolarHBondContact O-CG 3.19Å; P28-G234 WeakPolarHBondContact CD-O 3.42Å
29A70.5Confident73.4Confident71 Ų7160 Ų6059%0.58731%0.314SS*.THydrogen-bonded Turntrans-77.6-22.5174.700000112.8D27 R32D27-A29 PolarHBondContact O-N 3.47Å; D27-A29 VanDerWaalsContact OD1-CA 3.31Å; D27-A29 WeakPolarHBondContact OD1-CA 3.38Å; D27-A29 VanDerWaalsContact OD1-CB 3.22Å; D27-A29 WeakPolarHBondContact OD1-CB 3.38Å; D27-A29 PolarHBondContact OD1-N 2.81Å; A29-R32 WeakPolarHBondContact O-CD 3.23Å; A29-R32 WeakPolarHBondContact O-CG 3.16Å
30K78.7Confident76.1Confident141 Ų14158.1 Ų58.161%0.61330%0.295SS*.THydrogen-bonded Turntrans-91.7-27.6171-62177.1-172.8110.40112.6D27 R32 Y33D27-K30 HydrophobicContact CB-CB 4.08Å; D27-K30 HydrophobicContact CB-CD 3.97Å; D27-K30 HydrophobicContact CB-CG 4.04Å; D27-K30 PolarHBondContact O-N 2.79Å; D27-K30 PolarHBondContact OD1-N 3.44Å; D27-K30 WeakPolarHBondContact OD2-CD 3.45Å; D27-K30 VanDerWaalsContact OD2-CE 3.25Å; D27-K30 WeakPolarHBondContact OD2-CE 3.4Å; D27-K30 WeakPolarHBondContact OD2-CG 3.35Å; D27-K30 IonicContact OD2-NZ 3.25Å; D27-K30 PolarHBondContact OD2-NZ 3.22Å; K30-R32 PolarHBondContact O-N 2.89Å; K30-Y33 WeakPolarHBondContact O-CE2 3.34Å
31C85.6Confident78.6Confident4 Ų460.4 Ų60.43%0.02730%0.304CS..  trans-77.658.2-179.7-170.80000112.3D27 L96 G184 C185D27-C31 VanDerWaalsContact O-CB 3.3Å; D27-C31 WeakPolarHBondContact O-CB 3.41Å; D27-C31 PolarHBondContact O-N 3.45Å; C31-L96 HydrophobicContact CB-CD2 4.35Å; C31-G184 CarbonylContact C-O 3.6Å; C31-G184 CarbonylContact O-C 3.57Å; C31-G184 WeakPolarHBondContact O-CA 3.27Å; C31-G184 VanDerWaalsContact SG-C 3.57Å; C31-C185 HydrophobicContact CB-CB 4.02Å; C31-C185 WeakPolarHBondContact CB-SG 3.33Å; C31-C185 VanDerWaalsContact SG-CA 3.6Å; C31-C185 WeakPolarHBondContact SG-CB 3.13Å; C31-C185 PolarHBondContact SG-N 3.49Å; C31-C185 CovalentContact SG-SG 2.04Å; C31-C185 PolarHBondContact SG-SG 3.2Å
32R90Very high80.7Confident39 Ų3954.9 Ų54.915%0.14727%0.274CS..  trans-129.831.3-169.3-53.9-179.67690.3-15.5114P28 A29 K30 L99 D154P28-R32 WeakPolarHBondContact O-CG 3.19Å; A29-R32 WeakPolarHBondContact O-CD 3.23Å; A29-R32 WeakPolarHBondContact O-CG 3.16Å; K30-R32 PolarHBondContact O-N 2.89Å; R32-L99 HydrophobicContact CB-CD1 4.01Å; R32-L99 HydrophobicContact CG-CD1 3.75Å; R32-L99 VanDerWaalsContact CZ-CD1 3.45Å; R32-D154 IonicContact CZ-OD1 3.71Å; R32-D154 IonicContact NH1-OD1 3.45Å; R32-D154 PolarHBondContact NH1-OD1 3.03Å; R32-D154 VanDerWaalsContact NH2-CG 3.33Å; R32-D154 IonicContact NH2-OD1 3.87Å; R32-D154 PolarHBondContact NH2-OD1 3.1Å; R32-D154 IonicContact NH2-OD2 2.74Å; R32-D154 PolarHBondContact NH2-OD2 2.88Å; R32-D154 VanDerWaalsContact NH2-OD2 3.16Å
33Y91.8Very high82.5Confident108 Ų10857 Ų5742%0.42429%0.288SS..EExtended strand (participates in β ladder)trans-83.2141.9178.6-53.4-81.9000110.7K30 L35 Y183 G184 C185 V408K30-Y33 WeakPolarHBondContact O-CE2 3.34Å; Y33-L35 PolarHBondContact O-N 3.44Å; Y33-Y183 CarbonylContact O-C 3.54Å; Y33-Y183 VanDerWaalsContact O-CA 3.24Å; Y33-Y183 WeakPolarHBondContact O-CA 3.43Å; Y33-G184 PolarHBondContact N-O 3Å; Y33-G184 PolarHBondContact O-N 3.08Å; Y33-C185 HydrophobicContact CD2-CB 4.29Å; Y33-V408 HydrophobicContact CD1-CG2 4.08Å; Y33-V408 HydrophobicContact CE1-CG2 4.09Å
34A93.2Very high84.4Confident5 Ų551.7 Ų51.74%0.04127%0.269CS..EExtended strand (participates in β ladder)trans-59.9130.7170.900000110.1E181 Y183A34-E181 HydrophobicContact CB-CG 4.1Å; A34-Y183 HydrophobicContact CB-CD1 4.04Å; A34-Y183 HydrophobicContact CB-CE1 3.9Å
35L93.9Very high86.6Confident23 Ų2355.2 Ų55.212%0.1229%0.29CS..  trans-88.2-14.4-175.3-61.2-175.2000113.2Y33 I42 L91 H95 V97 L182Y33-L35 PolarHBondContact O-N 3.44Å; L35-I42 WeakPolarHBondContact O-CG1 3.4Å; L35-L91 HydrophobicContact CB-CD2 4.3Å; L35-L91 HydrophobicContact CD1-CD1 3.95Å; L35-L91 HydrophobicContact CD1-CD2 4.36Å; L35-H95 HydrophobicContact CD1-CB 4.14Å; L35-V97 HydrophobicContact CD1-CG2 4.13Å; L35-L182 HydrophobicContact CB-CB 4.27Å; L35-L182 WeakPolarHBondContact CB-O 3.34Å; L35-L182 HydrophobicContact CD1-CB 4Å; L35-L182 HydrophobicContact CG-CB 4.36Å; L35-L182 WeakPolarHBondContact CG-O 3.41Å; L35-L182 PolarHBondContact N-O 2.91Å
36G92.5Very high88.2Confident0 Ų053.9 Ų53.90%029%0.285CS..SBendtrans127.531.415400000116.5D39 R40 T41 I42 E181G36-D39 WeakPolarHBondContact CA-OD1 3.31Å; G36-R40 WeakPolarHBondContact O-CA 3.43Å; G36-R40 PolarHBondContact O-N 2.87Å; G36-T41 PolarHBondContact O-N 3.08Å; G36-I42 PolarHBondContact O-N 2.94Å; G36-I42 VanDerWaalsContact O-N 3.09Å; G36-E181 PolarHBondContact N-OE1 3.5Å
37M96.2Very high89.5Confident0 Ų052.8 Ų52.80%028%0.28CS..SBendtrans-68.3-50.4169.4-64.1-64.5-68.900110.3I42 I47 S62 R63 V89 V180 E181 L182M37-I42 HydrophobicContact CG-CD1 4.13Å; M37-I42 HydrophobicContact SD-CD1 3.87Å; M37-I42 HydrophobicContact SD-CG2 4.37Å; M37-I47 HydrophobicContact CE-CD1 3.67Å; M37-I47 HydrophobicContact CE-CG1 4.04Å; M37-I47 HydrophobicContact CE-CG2 4.08Å; M37-I47 HydrophobicContact SD-CD1 3.86Å; M37-I47 HydrophobicContact SD-CG1 4.07Å; M37-S62 WeakPolarHBondContact CE-OG 3.45Å; M37-R63 HydrophobicContact CE-CG 4.43Å; M37-R63 WeakPolarHBondContact O-CB 3.11Å; M37-R63 VanDerWaalsContact O-CD 3.29Å; M37-R63 WeakPolarHBondContact O-CD 3.17Å; M37-R63 WeakPolarHBondContact O-CG 3.46Å; M37-R63 PolarHBondContact O-NH1 3.44Å; M37-V89 HydrophobicContact CE-CG2 3.95Å; M37-V89 HydrophobicContact SD-CB 4.48Å; M37-V89 HydrophobicContact SD-CG1 3.83Å; M37-V89 HydrophobicContact SD-CG2 3.74Å; M37-V180 WeakPolarHBondContact CB-O 3.4Å; M37-V180 HydrophobicContact CE-CG2 3.81Å; M37-V180 HydrophobicContact CG-CG2 4.37Å; M37-V180 WeakPolarHBondContact CG-O 3.31Å; M37-E181 WeakPolarHBondContact CB-OE1 3.48Å; M37-E181 WeakPolarHBondContact CG-OE1 3.36Å; M37-E181 PolarHBondContact N-OE1 2.84Å; M37-E181 PolarHBondContact N-OE2 2.89Å; M37-L182 HydrophobicContact CG-CD1 3.93Å; M37-L182 HydrophobicContact SD-CD1 4.44Å
38Q92.6Very high90.8Very high83 Ų8352.4 Ų52.439%0.38828%0.281SS..SBendtrans-73.1-46.5-179-175.8178.212.700112.5R40 L64 E65 E181Q38-R40 PolarHBondContact O-N 3.36Å; Q38-L64 HydrophobicContact CB-CB 4.45Å; Q38-L64 WeakPolarHBondContact CG-O 3.28Å; Q38-E65 HydrophobicContact CG-CB 4.4Å; Q38-E181 WeakPolarHBondContact CB-OE2 3.5Å; Q38-E181 PolarHBondContact N-OE2 2.94Å
39D88.6Confident92.1Very high70 Ų7052.5 Ų52.537%0.37429%0.285SS..SBendtrans-77.9-6.2-177.879.76.8000114.2G36 T41 Q406G36-D39 WeakPolarHBondContact CA-OD1 3.31Å; D39-T41 VanDerWaalsContact C-N 3.3Å; D39-T41 VanDerWaalsContact CG-OG1 3.28Å; D39-T41 PolarHBondContact O-N 3.48Å; D39-T41 WeakPolarHBondContact OD1-CB 3.1Å; D39-T41 PolarHBondContact OD1-N 2.93Å; D39-T41 PolarHBondContact OD1-OG1 2.66Å; D39-T41 PolarHBondContact OD2-OG1 2.91Å; D39-Q406 PolarHBondContact OD2-NE2 3.33Å; D39-Q406 VanDerWaalsContact OD2-NE2 3.15Å
40R91.9Very high93.4Very high119 Ų11951.2 Ų51.245%0.44927%0.272SS..SBendtrans63.422.6-178.2-48-165-169.1-137.22.4115.7G36 Q38 I42 D68G36-R40 WeakPolarHBondContact O-CA 3.43Å; G36-R40 PolarHBondContact O-N 2.87Å; Q38-R40 PolarHBondContact O-N 3.36Å; R40-I42 PolarHBondContact O-N 2.97Å; R40-D68 IonicContact CZ-OD1 2.73Å; R40-D68 IonicContact CZ-OD2 2.7Å; R40-D68 VanDerWaalsContact CZ-OD2 3.26Å; R40-D68 IonicContact NH1-OD2 2.71Å; R40-D68 PolarHBondContact NH1-OD2 2.99Å; R40-D68 IonicContact NH2-OD1 2.65Å; R40-D68 PolarHBondContact NH2-OD1 2.99Å; R40-D68 IonicContact NH2-OD2 2.65Å; R40-D68 PolarHBondContact NH2-OD2 2.73Å
41T92.6Very high94.2Very high99 Ų9945.9 Ų45.961%0.60725%0.252SS*.  trans-60.9-33.7165.7-55.90000111.4G36 D39 P43G36-T41 PolarHBondContact O-N 3.08Å; D39-T41 VanDerWaalsContact C-N 3.3Å; D39-T41 VanDerWaalsContact CG-OG1 3.28Å; D39-T41 PolarHBondContact O-N 3.48Å; D39-T41 WeakPolarHBondContact OD1-CB 3.1Å; D39-T41 PolarHBondContact OD1-N 2.93Å; D39-T41 PolarHBondContact OD1-OG1 2.66Å; D39-T41 PolarHBondContact OD2-OG1 2.91Å; T41-P43 WeakPolarHBondContact O-CD 3.27Å
42I95.7Very high94.7Very high10 Ų1047.7 Ų47.75%0.05127%0.265CS..SBendtrans-82.6117.9169.9-58.1172.8000108.1L35 G36 M37 R40 D46 I47 R63 V89 L91L35-I42 WeakPolarHBondContact O-CG1 3.4Å; G36-I42 PolarHBondContact O-N 2.94Å; G36-I42 VanDerWaalsContact O-N 3.09Å; M37-I42 HydrophobicContact CG-CD1 4.13Å; M37-I42 HydrophobicContact SD-CD1 3.87Å; M37-I42 HydrophobicContact SD-CG2 4.37Å; R40-I42 PolarHBondContact O-N 2.97Å; I42-D46 HydrophobicContact CG2-CB 4.05Å; I42-I47 HydrophobicContact CG2-CD1 4.2Å; I42-I47 HydrophobicContact CG2-CG1 3.84Å; I42-R63 VanDerWaalsContact O-CZ 3.27Å; I42-R63 PolarHBondContact O-NH1 3.21Å; I42-R63 PolarHBondContact O-NH2 3.42Å; I42-V89 HydrophobicContact CD1-CG1 3.82Å; I42-V89 HydrophobicContact CG2-CG1 4.13Å; I42-L91 HydrophobicContact CD1-CD2 3.69Å
43P96.4Very high94.8Very high56 Ų5654.1 Ų54.136%0.36429%0.289SS..  trans-78.8162-177.933.3-36.4000112.7T41 S45 D46T41-P43 WeakPolarHBondContact O-CD 3.27Å; P43-S45 WeakPolarHBondContact CG-OG 3.33Å; P43-S45 PolarHBondContact O-N 2.05Å; P43-S45 VanDerWaalsContact O-N 3.15Å; P43-D46 HydrophobicContact CG-CB 4.14Å; P43-D46 WeakPolarHBondContact CG-OD2 3.28Å; P43-D46 PolarHBondContact O-N 2.84Å
44D95.8Very high94.9Very high76 Ų7650.7 Ų50.741%0.40628%0.281SS..G310 helixtrans-61.1-22.6-179.9-75.713.6000113.8D46 R60 R63D44-D46 PolarHBondContact O-N 2.83Å; D44-R60 HydrophobicContact CB-CB 4.14Å; D44-R60 WeakPolarHBondContact OD2-CB 3.36Å; D44-R63 IonicContact OD1-CZ 2.88Å; D44-R63 IonicContact OD1-NE 3.94Å; D44-R63 PolarHBondContact OD1-NE 3.48Å; D44-R63 IonicContact OD1-NH2 2.75Å; D44-R63 PolarHBondContact OD1-NH2 3.38Å
45S96.6Very high94.9Very high97 Ų9755.8 Ų55.868%0.67831%0.308SS*.G310 helixtrans-64.6-25173.952.30000113.5P43P43-S45 WeakPolarHBondContact CG-OG 3.33Å; P43-S45 PolarHBondContact O-N 2.05Å; P43-S45 VanDerWaalsContact O-N 3.15Å
46D97.4Very high94.9Very high19 Ų1956.5 Ų56.510%0.10231%0.314CS..G310 helixtrans-102.4-5.1-168.4-61.79.6000111.1I42 P43 D44 D90 Q92I42-D46 HydrophobicContact CG2-CB 4.05Å; P43-D46 HydrophobicContact CG-CB 4.14Å; P43-D46 WeakPolarHBondContact CG-OD2 3.28Å; P43-D46 PolarHBondContact O-N 2.84Å; D44-D46 PolarHBondContact O-N 2.83Å; D46-D90 HydrophobicContact CB-CB 4.26Å; D46-D90 PolarHBondContact O-N 2.78Å; D46-Q92 PolarHBondContact OD1-NE2 2.83Å; D46-Q92 VanDerWaalsContact OD2-CG 3.26Å; D46-Q92 WeakPolarHBondContact OD2-CG 3.41Å; D46-Q92 PolarHBondContact OD2-NE2 3.01Å
47I98.3Very high95Very high8 Ų856.8 Ų56.84%0.04132%0.316CS..EExtended strand (participates in β ladder)trans-107.6107.4176.5-52.9168.4000108.1M37 I42 A59 S62 R63 L87 Q88M37-I47 HydrophobicContact CE-CD1 3.67Å; M37-I47 HydrophobicContact CE-CG1 4.04Å; M37-I47 HydrophobicContact CE-CG2 4.08Å; M37-I47 HydrophobicContact SD-CD1 3.86Å; M37-I47 HydrophobicContact SD-CG1 4.07Å; I42-I47 HydrophobicContact CG2-CD1 4.2Å; I42-I47 HydrophobicContact CG2-CG1 3.84Å; I47-A59 HydrophobicContact CG2-CB 4.18Å; I47-A59 VanDerWaalsContact CG2-O 3.22Å; I47-A59 WeakPolarHBondContact CG2-O 3.36Å; I47-A59 WeakPolarHBondContact O-CB 3.16Å; I47-S62 WeakPolarHBondContact CG2-OG 3.28Å; I47-R63 HydrophobicContact CD1-CG 4.33Å; I47-R63 VanDerWaalsContact CD1-CZ 3.44Å; I47-L87 HydrophobicContact CG2-CD1 4Å; I47-Q88 WeakPolarHBondContact CA-O 3.1Å
48S98Very high95Very high43 Ų4357.3 Ų57.330%0.30132%0.321SS..EExtended strand (participates in β ladder)trans-127.5167.1-174.147.10000110.9Q88S48-Q88 PolarHBondContact N-O 3.33Å; S48-Q88 PolarHBondContact O-N 2.84Å; S48-Q88 VanDerWaalsContact O-O 3.11Å; S48-Q88 PolarHBondContact OG-NE2 2.94Å
49A97.9Very high95.2Very high31 Ų3153.9 Ų53.926%0.25631%0.306SS..EExtended strand (participates in β ladder)trans-148.1163.117900000111.8S51 A59 W73 Y86A49-S51 VanDerWaalsContact C-N 3.32Å; A49-S51 WeakPolarHBondContact CB-O 3.47Å; A49-A59 HydrophobicContact CB-CB 3.86Å; A49-W73 HydrophobicContact CB-CZ2 3.81Å; A49-W73 VanDerWaalsContact CB-NE1 3.27Å; A49-Y86 CarbonylContact C-O 3.38Å; A49-Y86 VanDerWaalsContact CA-O 3.25Å; A49-Y86 WeakPolarHBondContact CA-O 3.37Å; A49-Y86 WeakPolarHBondContact CB-O 3.33Å
50S96.9Very high95.6Very high45 Ų4553.7 Ų53.732%0.31530%0.3SS..SBendtrans-60-40.5169.947.60000112.9E85 Y86S50-E85 WeakPolarHBondContact CB-OE2 3.47Å; S50-E85 VanDerWaalsContact OG-CA 3.32Å; S50-E85 WeakPolarHBondContact OG-CA 3.29Å; S50-E85 PolarHBondContact OG-OE2 2.99Å; S50-Y86 PolarHBondContact N-O 2.91Å; S50-Y86 PolarHBondContact OG-N 3.02Å; S50-Y86 PolarHBondContact OG-O 2.88Å
51S96.8Very high95.8Very high28 Ų2849.3 Ų49.320%0.19629%0.285CS..  trans-158.2177.2178.972.10000110.5A49 W73 A76 E85A49-S51 VanDerWaalsContact C-N 3.32Å; A49-S51 WeakPolarHBondContact CB-O 3.47Å; S51-W73 PolarHBondContact O-NE1 2.87Å; S51-A76 PolarHBondContact OG-N 3.48Å; S51-E85 WeakPolarHBondContact CB-OE2 3.19Å; S51-E85 PolarHBondContact OG-OE2 3.01Å
52S95.8Very high96.1Very high43 Ų4344.6 Ų44.630%0.30126%0.256SS..  trans-150.9133.2169.9-59.90000109.4S54 C74S52-S54 PolarHBondContact O-N 2.84Å; S52-C74 CarbonylContact C-O 3.53Å; S52-C74 WeakPolarHBondContact CA-O 3.48Å
53W92.5Very high96.2Very high174 Ų17444.3 Ų44.366%0.65925%0.254SS*.SBendtrans-59.8-36.8-175.5176.3-81.7000112.6T57 C74W53-T57 WeakPolarHBondContact CB-OG1 3.46Å; W53-C74 HydrophobicContact CB-CB 4.45Å; W53-C74 PolarHBondContact N-O 2.87Å
54S93.8Very high96.1Very high36 Ų3641.8 Ų41.825%0.25224%0.238SC..SBendtrans-150.8166.6174.854.60000109.5S52 S56 T57 A58S52-S54 PolarHBondContact O-N 2.84Å; S54-S56 WeakPolarHBondContact CB-OG 3.22Å; S54-S56 PolarHBondContact O-N 2.96Å; S54-S56 PolarHBondContact OG-OG 3.07Å; S54-T57 PolarHBondContact N-OG1 2.91Å; S54-T57 CarbonylContact O-C 3.6Å; S54-T57 VanDerWaalsContact O-C 3.3Å; S54-T57 WeakPolarHBondContact O-CA 3.39Å; S54-T57 PolarHBondContact O-N 3.03Å; S54-T57 PolarHBondContact O-OG1 3.06Å; S54-T57 PolarHBondContact OG-N 3.41Å; S54-T57 PolarHBondContact OG-OG1 3.14Å; S54-A58 PolarHBondContact O-N 3.49Å; S54-A58 VanDerWaalsContact O-N 3.14Å
55D93.6Very high96Very high112 Ų11242.9 Ų42.960%0.59924%0.24SC*.G310 helixtrans-64.4-26.4171.3-174.963.8000112.3T57 A58 R60 H61D55-T57 PolarHBondContact O-N 3.19Å; D55-A58 VanDerWaalsContact O-CB 3.24Å; D55-A58 WeakPolarHBondContact O-CB 3.24Å; D55-A58 PolarHBondContact O-N 2.74Å; D55-R60 PolarHBondContact O-NH2 2.87Å; D55-R60 IonicContact OD1-CZ 2.81Å; D55-R60 IonicContact OD1-NH1 3.1Å; D55-R60 PolarHBondContact OD1-NH1 2.86Å; D55-R60 IonicContact OD1-NH2 3.48Å; D55-R60 PolarHBondContact OD1-NH2 2.85Å; D55-R60 VanDerWaalsContact OD1-NH2 3.12Å; D55-R60 IonicContact OD2-CZ 2.92Å; D55-R60 IonicContact OD2-NH1 3.8Å; D55-R60 IonicContact OD2-NH2 2.7Å; D55-R60 PolarHBondContact OD2-NH2 2.9Å; D55-H61 PolarHBondContact O-NE2 3.34Å
56S92.4Very high95.8Very high37 Ų3738.8 Ų38.826%0.25921%0.212SC..G310 helixtrans-70.6-13.8170.358.60000113.8S54 H61 D70S54-S56 WeakPolarHBondContact CB-OG 3.22Å; S54-S56 PolarHBondContact O-N 2.96Å; S54-S56 PolarHBondContact OG-OG 3.07Å; S56-H61 WeakPolarHBondContact CA-NE2 3.21Å; S56-H61 PolarHBondContact O-CD2 3.23Å; S56-D70 VanDerWaalsContact CB-CG 3.47Å; S56-D70 WeakPolarHBondContact CB-OD2 3.43Å; S56-D70 PolarHBondContact O-N 3.36Å; S56-D70 PolarHBondContact OG-OD2 2.66Å
57T95.1Very high95.5Very high7 Ų742.7 Ų42.74%0.04324%0.241CC..G310 helixtrans-119.427170.8590000112.4W53 S54 D55 D70 A72 W73 C74W53-T57 WeakPolarHBondContact CB-OG1 3.46Å; S54-T57 PolarHBondContact N-OG1 2.91Å; S54-T57 CarbonylContact O-C 3.6Å; S54-T57 VanDerWaalsContact O-C 3.3Å; S54-T57 WeakPolarHBondContact O-CA 3.39Å; S54-T57 PolarHBondContact O-N 3.03Å; S54-T57 PolarHBondContact O-OG1 3.06Å; S54-T57 PolarHBondContact OG-N 3.41Å; S54-T57 PolarHBondContact OG-OG1 3.14Å; D55-T57 PolarHBondContact O-N 3.19Å; T57-D70 HydrophobicContact CG2-CB 3.99Å; T57-A72 WeakPolarHBondContact CA-O 3.46Å; T57-W73 WeakPolarHBondContact O-CA 3.43Å; T57-W73 VanDerWaalsContact O-CD1 3.24Å; T57-C74 HydrophobicContact CG2-CB 4.18Å; T57-C74 PolarHBondContact O-N 2.91Å
58A96.4Very high95.1Very high11 Ų1144.7 Ų44.79%0.09125%0.251CS..  trans-62.6158.5175.600000113.4S54 D55 R60 H61S54-A58 PolarHBondContact O-N 3.49Å; S54-A58 VanDerWaalsContact O-N 3.14Å; D55-A58 VanDerWaalsContact O-CB 3.24Å; D55-A58 WeakPolarHBondContact O-CB 3.24Å; D55-A58 PolarHBondContact O-N 2.74Å; A58-R60 VanDerWaalsContact C-N 3.26Å; A58-R60 HydrophobicContact CB-CG 4.22Å; A58-R60 PolarHBondContact O-N 3.34Å; A58-R60 VanDerWaalsContact O-N 3.1Å; A58-H61 WeakPolarHBondContact O-CB 3.49Å; A58-H61 PolarHBondContact O-N 2.85Å
59A97.2Very high94.7Very high11 Ų1144.6 Ų44.69%0.09126%0.258CS..G310 helixtrans-50.8-38.9-175.400000114.3I47 A49 H61 S62 L87I47-A59 HydrophobicContact CG2-CB 4.18Å; I47-A59 VanDerWaalsContact CG2-O 3.22Å; I47-A59 WeakPolarHBondContact CG2-O 3.36Å; I47-A59 WeakPolarHBondContact O-CB 3.16Å; A49-A59 HydrophobicContact CB-CB 3.86Å; A59-H61 PolarHBondContact O-N 3.08Å; A59-H61 VanDerWaalsContact O-N 3.09Å; A59-S62 WeakPolarHBondContact O-CB 3.37Å; A59-S62 PolarHBondContact O-N 3.42Å; A59-S62 PolarHBondContact O-OG 3.44Å; A59-L87 HydrophobicContact CB-CD1 4.08Å
60R96Very high94.3Very high65 Ų6546.7 Ų46.725%0.24527%0.265CS..G310 helixtrans-53.9-25.3175.464.8-174.7-174.6-107.2-7.1115.1D44 D55 A58 S62D44-R60 HydrophobicContact CB-CB 4.14Å; D44-R60 WeakPolarHBondContact OD2-CB 3.36Å; D55-R60 PolarHBondContact O-NH2 2.87Å; D55-R60 IonicContact OD1-CZ 2.81Å; D55-R60 IonicContact OD1-NH1 3.1Å; D55-R60 PolarHBondContact OD1-NH1 2.86Å; D55-R60 IonicContact OD1-NH2 3.48Å; D55-R60 PolarHBondContact OD1-NH2 2.85Å; D55-R60 VanDerWaalsContact OD1-NH2 3.12Å; D55-R60 IonicContact OD2-CZ 2.92Å; D55-R60 IonicContact OD2-NH1 3.8Å; D55-R60 IonicContact OD2-NH2 2.7Å; D55-R60 PolarHBondContact OD2-NH2 2.9Å; A58-R60 VanDerWaalsContact C-N 3.26Å; A58-R60 HydrophobicContact CB-CG 4.22Å; A58-R60 PolarHBondContact O-N 3.34Å; A58-R60 VanDerWaalsContact O-N 3.1Å; R60-S62 VanDerWaalsContact C-N 3.27Å; R60-S62 PolarHBondContact O-N 3.3Å
61H97.2Very high93.9Very high28 Ų2844.6 Ų44.613%0.1325%0.25CS..G310 helixtrans-84.92.9179-56.5-46.1000113D55 S56 A58 A59 R63 D68 A72D55-H61 PolarHBondContact O-NE2 3.34Å; S56-H61 WeakPolarHBondContact CA-NE2 3.21Å; S56-H61 PolarHBondContact O-CD2 3.23Å; A58-H61 WeakPolarHBondContact O-CB 3.49Å; A58-H61 PolarHBondContact O-N 2.85Å; A59-H61 PolarHBondContact O-N 3.08Å; A59-H61 VanDerWaalsContact O-N 3.09Å; H61-R63 PolarHBondContact O-N 2.86Å; H61-D68 VanDerWaalsContact ND1-CB 3.32Å; H61-D68 WeakPolarHBondContact ND1-CB 3.29Å; H61-A72 CarbonylContact O-C 3.38Å; H61-A72 VanDerWaalsContact O-CA 3.31Å; H61-A72 WeakPolarHBondContact O-CA 3.25Å
62S97.6Very high93.9Very high0 Ų043.3 Ų43.30%024%0.241CC..  trans-79.416177.268.30000115M37 I47 A59 R60 L87 L178 R179 V180M37-S62 WeakPolarHBondContact CE-OG 3.45Å; I47-S62 WeakPolarHBondContact CG2-OG 3.28Å; A59-S62 WeakPolarHBondContact O-CB 3.37Å; A59-S62 PolarHBondContact O-N 3.42Å; A59-S62 PolarHBondContact O-OG 3.44Å; R60-S62 VanDerWaalsContact C-N 3.27Å; R60-S62 PolarHBondContact O-N 3.3Å; S62-L87 VanDerWaalsContact CB-CD2 3.48Å; S62-L87 WeakPolarHBondContact OG-CD1 3.48Å; S62-L87 WeakPolarHBondContact OG-CD2 3.47Å; S62-L178 WeakPolarHBondContact CA-O 3.42Å; S62-R179 CarbonylContact O-C 3.24Å; S62-R179 VanDerWaalsContact O-CA 3.24Å; S62-R179 WeakPolarHBondContact O-CA 3.44Å; S62-V180 PolarHBondContact O-N 2.86Å
63R97.9Very high94Very high3 Ų341.2 Ų41.21%0.01123%0.226CC..BIsolated β-bridgetrans-79.9130.1-177.3-63.7174.9179.1-77.11.9110.6M37 I42 D44 I47 H61 S66 R179M37-R63 HydrophobicContact CE-CG 4.43Å; M37-R63 WeakPolarHBondContact O-CB 3.11Å; M37-R63 VanDerWaalsContact O-CD 3.29Å; M37-R63 WeakPolarHBondContact O-CD 3.17Å; M37-R63 WeakPolarHBondContact O-CG 3.46Å; M37-R63 PolarHBondContact O-NH1 3.44Å; I42-R63 VanDerWaalsContact O-CZ 3.27Å; I42-R63 PolarHBondContact O-NH1 3.21Å; I42-R63 PolarHBondContact O-NH2 3.42Å; D44-R63 IonicContact OD1-CZ 2.88Å; D44-R63 IonicContact OD1-NE 3.94Å; D44-R63 PolarHBondContact OD1-NE 3.48Å; D44-R63 IonicContact OD1-NH2 2.75Å; D44-R63 PolarHBondContact OD1-NH2 3.38Å; I47-R63 HydrophobicContact CD1-CG 4.33Å; I47-R63 VanDerWaalsContact CD1-CZ 3.44Å; H61-R63 PolarHBondContact O-N 2.86Å; R63-S66 WeakPolarHBondContact O-CB 3.4Å; R63-S66 PolarHBondContact O-N 3.35Å; R63-S66 VanDerWaalsContact O-N 3.12Å; R63-R179 VanDerWaalsContact O-CD 3.27Å; R63-R179 WeakPolarHBondContact O-CD 3.18Å; R63-R179 WeakPolarHBondContact O-CG 3.45Å
64L95.8Very high94.2Very high4 Ų433.4 Ų33.42%0.02120%0.198CC..THydrogen-bonded Turntrans-53.4141.6174.9-154.183000111.4Q38 S66 Q103 V150 V180 E181Q38-L64 HydrophobicContact CB-CB 4.45Å; Q38-L64 WeakPolarHBondContact CG-O 3.28Å; L64-S66 PolarHBondContact O-N 2.95Å; L64-Q103 HydrophobicContact CD1-CB 3.65Å; L64-V150 HydrophobicContact CD1-CG1 4.27Å; L64-V150 HydrophobicContact CD1-CG2 4.19Å; L64-V150 HydrophobicContact CD2-CG1 4Å; L64-V150 HydrophobicContact CD2-CG2 4.08Å; L64-V150 HydrophobicContact CG-CG2 4.18Å; L64-V180 PolarHBondContact N-O 3.05Å; L64-V180 VanDerWaalsContact N-O 3.11Å; L64-E181 HydrophobicContact CB-CB 3.87Å; L64-E181 HydrophobicContact CD2-CB 3.83Å; L64-E181 HydrophobicContact CG-CB 4.3Å
65E93.2Very high94.4Very high98 Ų9832.1 Ų32.146%0.45819%0.189SC..THydrogen-bonded Turntrans55.92.9-174.5-61.1-53.7144.200116.8Q38 Q103 V150Q38-E65 HydrophobicContact CG-CB 4.4Å; E65-Q103 VanDerWaalsContact CD-NE2 3.34Å; E65-Q103 PolarHBondContact OE1-NE2 3.03Å; E65-Q103 PolarHBondContact OE2-NE2 3.41Å; E65-V150 WeakPolarHBondContact OE1-CG2 3.2Å
66S92.2Very high94.2Very high12 Ų1229 Ų298%0.08418%0.179CC..  trans-72.1147.8174.2-1760000111.6R63 L64 D68 R179R63-S66 WeakPolarHBondContact O-CB 3.4Å; R63-S66 PolarHBondContact O-N 3.35Å; R63-S66 VanDerWaalsContact O-N 3.12Å; L64-S66 PolarHBondContact O-N 2.95Å; S66-D68 WeakPolarHBondContact OG-CB 3.46Å; S66-D68 VanDerWaalsContact OG-CG 3.29Å; S66-D68 PolarHBondContact OG-N 2.79Å; S66-D68 VanDerWaalsContact OG-N 3.13Å; S66-D68 PolarHBondContact OG-OD1 2.93Å; S66-R179 VanDerWaalsContact O-CD 3.32Å; S66-R179 WeakPolarHBondContact O-CD 3.32Å; S66-R179 PolarHBondContact O-NH1 2.78Å
67S90.6Very high93.8Very high101 Ų10128.8 Ų28.871%0.70618%0.183SC*.  trans-11611.8169.854.90000112.5
68D89.6Confident93.4Very high49 Ų4931.5 Ų31.526%0.26220%0.201SC..  trans-60.8144.3177.9-65.531.3000111.9R40 H61 S66 G71R40-D68 IonicContact CZ-OD1 2.73Å; R40-D68 IonicContact CZ-OD2 2.7Å; R40-D68 VanDerWaalsContact CZ-OD2 3.26Å; R40-D68 IonicContact NH1-OD2 2.71Å; R40-D68 PolarHBondContact NH1-OD2 2.99Å; R40-D68 IonicContact NH2-OD1 2.65Å; R40-D68 PolarHBondContact NH2-OD1 2.99Å; R40-D68 IonicContact NH2-OD2 2.65Å; R40-D68 PolarHBondContact NH2-OD2 2.73Å; H61-D68 VanDerWaalsContact ND1-CB 3.32Å; H61-D68 WeakPolarHBondContact ND1-CB 3.29Å; S66-D68 WeakPolarHBondContact OG-CB 3.46Å; S66-D68 VanDerWaalsContact OG-CG 3.29Å; S66-D68 PolarHBondContact OG-N 2.79Å; S66-D68 VanDerWaalsContact OG-N 3.13Å; S66-D68 PolarHBondContact OG-OD1 2.93Å; D68-G71 WeakPolarHBondContact O-CA 3.26Å; D68-G71 PolarHBondContact O-N 3.45Å
69G90.8Very high92.8Very high42 Ų4231.1 Ų31.143%0.43320%0.198SC..THydrogen-bonded Turntrans64.1-136.3-178.500000112.5G71G69-G71 PolarHBondContact O-N 3.33Å
70D88.9Confident92.1Very high75 Ų7533.8 Ų33.840%0.40121%0.208SC..THydrogen-bonded Turntrans-87.416.7170.8-71.2-25.9000112.1S56 T57 R105 A107S56-D70 VanDerWaalsContact CB-CG 3.47Å; S56-D70 WeakPolarHBondContact CB-OD2 3.43Å; S56-D70 PolarHBondContact O-N 3.36Å; S56-D70 PolarHBondContact OG-OD2 2.66Å; T57-D70 HydrophobicContact CG2-CB 3.99Å; D70-R105 VanDerWaalsContact O-CD 3.23Å; D70-R105 WeakPolarHBondContact O-CD 3.49Å; D70-R105 VanDerWaalsContact O-CG 3.26Å; D70-R105 WeakPolarHBondContact O-CG 3.38Å; D70-R105 PolarHBondContact O-NH1 2.95Å; D70-A107 WeakPolarHBondContact O-CB 3.26Å
71G88.9Confident91Very high1 Ų134.9 Ų34.91%0.0122%0.223CC..SBendtrans9012.3164.900000117.6D68 G69 R179D68-G71 WeakPolarHBondContact O-CA 3.26Å; D68-G71 PolarHBondContact O-N 3.45Å; G69-G71 PolarHBondContact O-N 3.33Å; G71-R179 VanDerWaalsContact O-CD 3.28Å; G71-R179 WeakPolarHBondContact O-CD 3.49Å; G71-R179 PolarHBondContact O-NE 2.81Å
72A96.5Very high90Very high0 Ų039.4 Ų39.40%024%0.243CC..SBendtrans-171.7169.8168.300000111.1T57 H61 R105 C177 R179T57-A72 WeakPolarHBondContact CA-O 3.46Å; H61-A72 CarbonylContact O-C 3.38Å; H61-A72 VanDerWaalsContact O-CA 3.31Å; H61-A72 WeakPolarHBondContact O-CA 3.25Å; A72-R105 HydrophobicContact CB-CB 3.59Å; A72-R105 HydrophobicContact CB-CG 3.67Å; A72-C177 HydrophobicContact CB-CB 3.78Å; A72-R179 HydrophobicContact CB-CG 3.99Å
73W98Very high89.4Confident0 Ų041 Ų410%025%0.25CS..BIsolated β-bridgetrans-79.9140.7156166.772.6000110.8A49 S51 T57 P75 Y86 L87 P168 C177 L178A49-W73 HydrophobicContact CB-CZ2 3.81Å; A49-W73 VanDerWaalsContact CB-NE1 3.27Å; S51-W73 PolarHBondContact O-NE1 2.87Å; T57-W73 WeakPolarHBondContact O-CA 3.43Å; T57-W73 VanDerWaalsContact O-CD1 3.24Å; W73-P75 HydrophobicContact CH2-CG 3.61Å; W73-P75 HydrophobicContact CZ2-CB 4.26Å; W73-P75 HydrophobicContact CZ2-CG 3.67Å; W73-P75 HydrophobicContact CZ3-CG 4.22Å; W73-Y86 WeakPolarHBondContact CZ2-O 3.18Å; W73-L87 HydrophobicContact CB-CD1 4.46Å; W73-L87 HydrophobicContact CD2-CB 4.27Å; W73-L87 HydrophobicContact CD2-CD1 4.1Å; W73-L87 HydrophobicContact CE3-CB 3.77Å; W73-L87 HydrophobicContact CE3-CD1 4.27Å; W73-L87 HydrophobicContact CE3-CG 4.43Å; W73-L87 HydrophobicContact CG-CD1 4.19Å; W73-L87 HydrophobicContact CH2-CB 4.02Å; W73-L87 VanDerWaalsContact CH2-N 3.31Å; W73-L87 HydrophobicContact CZ3-CB 3.64Å; W73-P168 HydrophobicContact CH2-CG 3.94Å; W73-P168 HydrophobicContact CZ3-CG 3.95Å; W73-C177 CarbonylContact O-C 3.58Å; W73-C177 WeakPolarHBondContact O-CA 3.28Å; W73-C177 VanDerWaalsContact O-CB 3.23Å; W73-C177 WeakPolarHBondContact O-CB 3.46Å; W73-L178 HydrophobicContact CE3-CB 4.1Å; W73-L178 HydrophobicContact CZ3-CB 4.4Å; W73-L178 HydrophobicContact CZ3-CD1 4.31Å; W73-L178 PolarHBondContact N-O 2.9Å; W73-L178 PolarHBondContact O-N 3.25Å
74C97.1Very high89.2Confident10 Ų1045.7 Ų45.77%0.06827%0.272CS..  trans-138.6130.3175.2-50.10000109.7S52 W53 T57 C177S52-C74 CarbonylContact C-O 3.53Å; S52-C74 WeakPolarHBondContact CA-O 3.48Å; W53-C74 HydrophobicContact CB-CB 4.45Å; W53-C74 PolarHBondContact N-O 2.87Å; T57-C74 HydrophobicContact CG2-CB 4.18Å; T57-C74 PolarHBondContact O-N 2.91Å; C74-C177 HydrophobicContact CB-CB 4.11Å; C74-C177 WeakPolarHBondContact CB-SG 3.09Å; C74-C177 WeakPolarHBondContact SG-CB 3.42Å; C74-C177 CovalentContact SG-SG 2.04Å; C74-C177 PolarHBondContact SG-SG 2.81Å
75P96.8Very high89.2Confident8 Ų847.1 Ų47.15%0.05228%0.279CS..  trans-59.8149.8174.6-20.330.8000113W73 V79 E85 P168 V176W73-P75 HydrophobicContact CH2-CG 3.61Å; W73-P75 HydrophobicContact CZ2-CB 4.26Å; W73-P75 HydrophobicContact CZ2-CG 3.67Å; W73-P75 HydrophobicContact CZ3-CG 4.22Å; P75-V79 HydrophobicContact CB-CG2 4.28Å; P75-V79 HydrophobicContact CG-CG2 3.85Å; P75-E85 HydrophobicContact CB-CB 4.02Å; P75-E85 HydrophobicContact CB-CG 3.84Å; P75-E85 HydrophobicContact CG-CB 4.08Å; P75-E85 HydrophobicContact CG-CG 4.41Å; P75-P168 HydrophobicContact CG-CG 4.34Å; P75-V176 WeakPolarHBondContact CD-O 3.47Å; P75-V176 HydrophobicContact CG-CG2 4.49Å
76A90.9Very high89.4Confident48 Ų4844.9 Ų44.940%0.39727%0.267SS..SBendtrans-75.3-39.7170.800000112.2S51S51-A76 PolarHBondContact OG-N 3.48Å
77G82.5Confident89.7Confident32 Ų3244.3 Ų44.333%0.3326%0.263SS..SBendtrans-79.5150.9177.600000112.6V79G77-V79 PolarHBondContact O-N 2.98Å
78S86.8Confident90.1Very high63 Ų6340.9 Ų40.944%0.44124%0.235SC..  trans-66.1119.7164.4-1690000109.3F80S78-F80 PolarHBondContact O-N 3.5Å; S78-F80 PolarHBondContact OG-O 2.87Å
79V84.9Confident90.5Very high3 Ų338.5 Ų38.52%0.01822%0.223CC..  trans-60.8-32.1178.1177.60000111.8P75 G77 K82 E83 E85 P168 A170 V176P75-V79 HydrophobicContact CB-CG2 4.28Å; P75-V79 HydrophobicContact CG-CG2 3.85Å; G77-V79 PolarHBondContact O-N 2.98Å; V79-K82 PolarHBondContact O-N 3.12Å; V79-E83 PolarHBondContact O-N 3Å; V79-E85 HydrophobicContact CG2-CB 4.04Å; V79-E85 HydrophobicContact CG2-CG 4.16Å; V79-P168 WeakPolarHBondContact CG1-O 3.46Å; V79-P168 HydrophobicContact CG2-CG 4.25Å; V79-A170 HydrophobicContact CB-CB 4.43Å; V79-V176 HydrophobicContact CB-CG2 4.12Å; V79-V176 HydrophobicContact CG2-CG2 3.41Å; V79-V176 VanDerWaalsContact CG2-CG2 3.41Å
80F81Confident90.8Very high67 Ų6737.6 Ų37.629%0.29421%0.208SC..THydrogen-bonded Turntrans-83.3136.8173.9178.2-86000111S78 A170 R172 V173S78-F80 PolarHBondContact O-N 3.5Å; S78-F80 PolarHBondContact OG-O 2.87Å; F80-A170 HydrophobicContact CB-CB 4.43Å; F80-R172 VanDerWaalsContact CB-O 3.3Å; F80-R172 WeakPolarHBondContact CB-O 3.36Å; F80-V173 HydrophobicContact CD1-CG2 3.82Å
81P74.4Confident91.2Very high89 Ų8934.8 Ų34.858%0.57819%0.193SC*.THydrogen-bonded Turncis-96-4.24.337.4-36.5000114.2
82K76.4Confident91.4Very high123 Ų12339.6 Ų39.654%0.53522%0.215SC..THydrogen-bonded Turntrans-81.9-28.3-161.8-66.6-157.1-175.7-173.30115.4V79 E84V79-K82 PolarHBondContact O-N 3.12Å; K82-E84 HydrophobicContact CB-CB 4.29Å; K82-E84 HydrophobicContact CB-CG 3.99Å; K82-E84 HydrophobicContact CD-CG 4.12Å; K82-E84 VanDerWaalsContact CD-OE1 3.25Å; K82-E84 WeakPolarHBondContact CD-OE1 3.43Å; K82-E84 WeakPolarHBondContact CD-OE2 3.46Å; K82-E84 IonicContact NZ-OE1 3.67Å; K82-E84 PolarHBondContact NZ-OE1 2.86Å; K82-E84 IonicContact NZ-OE2 2.72Å; K82-E84 PolarHBondContact NZ-OE2 3.26Å; K82-E84 PolarHBondContact O-N 3.16Å
83E84.9Confident91.2Very high34 Ų3446.3 Ų46.316%0.15924%0.24CC..  trans58.929.5-177.4-52.8174.5-178.700112.5V79 R119 Y167 R169V79-E83 PolarHBondContact O-N 3Å; E83-R119 IonicContact OE2-CZ 3.85Å; E83-R119 IonicContact OE2-NH1 2.95Å; E83-R119 PolarHBondContact OE2-NH1 2.79Å; E83-R119 IonicContact OE2-NH2 3.76Å; E83-R119 PolarHBondContact OE2-NH2 3.42Å; E83-Y167 WeakPolarHBondContact O-CD1 3.5Å; E83-R169 VanDerWaalsContact CD-NE 3.28Å; E83-R169 HydrophobicContact CG-CG 4.36Å; E83-R169 IonicContact OE1-CZ 2.71Å; E83-R169 IonicContact OE1-NE 3.22Å; E83-R169 PolarHBondContact OE1-NE 2.91Å; E83-R169 IonicContact OE1-NH2 3.18Å; E83-R169 PolarHBondContact OE1-NH2 3.26Å; E83-R169 IonicContact OE2-NE 3.57Å; E83-R169 PolarHBondContact OE2-NE 2.8Å; E83-R169 VanDerWaalsContact OE2-NE 3.16Å
84E92.1Very high91.1Very high100 Ų10047.1 Ų47.147%0.46725%0.245SC..  trans-84-24.5-178.1-83.2173.5-175.200114.1K82 Y86K82-E84 HydrophobicContact CB-CB 4.29Å; K82-E84 HydrophobicContact CB-CG 3.99Å; K82-E84 HydrophobicContact CD-CG 4.12Å; K82-E84 VanDerWaalsContact CD-OE1 3.25Å; K82-E84 WeakPolarHBondContact CD-OE1 3.43Å; K82-E84 WeakPolarHBondContact CD-OE2 3.46Å; K82-E84 IonicContact NZ-OE1 3.67Å; K82-E84 PolarHBondContact NZ-OE1 2.86Å; K82-E84 IonicContact NZ-OE2 2.72Å; K82-E84 PolarHBondContact NZ-OE2 3.26Å; K82-E84 PolarHBondContact O-N 3.16Å; E84-Y86 WeakPolarHBondContact O-CD1 3.45Å
85E96Very high91Very high35 Ų3547.9 Ų47.916%0.16425%0.247CC..  trans-72.6145.5-178.3-62.7-67.5148.200111.9S50 S51 P75 V79 Y167 P168S50-E85 WeakPolarHBondContact CB-OE2 3.47Å; S50-E85 VanDerWaalsContact OG-CA 3.32Å; S50-E85 WeakPolarHBondContact OG-CA 3.29Å; S50-E85 PolarHBondContact OG-OE2 2.99Å; S51-E85 WeakPolarHBondContact CB-OE2 3.19Å; S51-E85 PolarHBondContact OG-OE2 3.01Å; P75-E85 HydrophobicContact CB-CB 4.02Å; P75-E85 HydrophobicContact CB-CG 3.84Å; P75-E85 HydrophobicContact CG-CB 4.08Å; P75-E85 HydrophobicContact CG-CG 4.41Å; V79-E85 HydrophobicContact CG2-CB 4.04Å; V79-E85 HydrophobicContact CG2-CG 4.16Å; E85-Y167 VanDerWaalsContact O-CD1 3.3Å; E85-Y167 WeakPolarHBondContact O-CD1 3.24Å; E85-P168 WeakPolarHBondContact O-CD 3.37Å
86Y97.8Very high90.9Very high51 Ų5147.7 Ų47.720%0.225%0.245CC..  trans-152.2149.7178.960.7-89.2000113.6A49 S50 W73 E84 Q88 R165 F166 Y167A49-Y86 CarbonylContact C-O 3.38Å; A49-Y86 VanDerWaalsContact CA-O 3.25Å; A49-Y86 WeakPolarHBondContact CA-O 3.37Å; A49-Y86 WeakPolarHBondContact CB-O 3.33Å; S50-Y86 PolarHBondContact N-O 2.91Å; S50-Y86 PolarHBondContact OG-N 3.02Å; S50-Y86 PolarHBondContact OG-O 2.88Å; W73-Y86 WeakPolarHBondContact CZ2-O 3.18Å; E84-Y86 WeakPolarHBondContact O-CD1 3.45Å; Y86-Q88 HydrophobicContact CD2-CB 4.04Å; Y86-Q88 HydrophobicContact CE2-CB 4.09Å; Y86-R165 HydrophobicContact CD2-CG 3.73Å; Y86-R165 HydrophobicContact CE2-CG 4.3Å; Y86-R165 HydrophobicContact CG-CG 4.26Å; Y86-R165 PolarHBondContact OH-NH2 3Å; Y86-F166 VanDerWaalsContact CA-O 3.25Å; Y86-F166 WeakPolarHBondContact CA-O 3.45Å; Y86-Y167 HydrophobicContact CD1-CD1 4.48Å; Y86-Y167 AromaticContact CD1-CE1 3.64Å; Y86-Y167 HydrophobicContact CD1-CE1 3.64Å; Y86-Y167 AromaticContact CD1-CZ 3.7Å; Y86-Y167 HydrophobicContact CG-CE1 4.05Å; Y86-Y167 HydrophobicContact CG-CE2 4.38Å; Y86-Y167 AromaticContact CG-CZ 3.89Å
87L98.5Very high91.2Very high0 Ų045.4 Ų45.40%023%0.227CC..EExtended strand (participates in β ladder)trans-91.2139156.6-179.872.2000108.1I47 A59 S62 W73 R165 F166 V180I47-L87 HydrophobicContact CG2-CD1 4Å; A59-L87 HydrophobicContact CB-CD1 4.08Å; S62-L87 VanDerWaalsContact CB-CD2 3.48Å; S62-L87 WeakPolarHBondContact OG-CD1 3.48Å; S62-L87 WeakPolarHBondContact OG-CD2 3.47Å; W73-L87 HydrophobicContact CB-CD1 4.46Å; W73-L87 HydrophobicContact CD2-CB 4.27Å; W73-L87 HydrophobicContact CD2-CD1 4.1Å; W73-L87 HydrophobicContact CE3-CB 3.77Å; W73-L87 HydrophobicContact CE3-CD1 4.27Å; W73-L87 HydrophobicContact CE3-CG 4.43Å; W73-L87 HydrophobicContact CG-CD1 4.19Å; W73-L87 HydrophobicContact CH2-CB 4.02Å; W73-L87 VanDerWaalsContact CH2-N 3.31Å; W73-L87 HydrophobicContact CZ3-CB 3.64Å; L87-R165 CarbonylContact O-C 3.57Å; L87-R165 WeakPolarHBondContact O-CA 3.46Å; L87-F166 HydrophobicContact CB-CB 4.39Å; L87-F166 PolarHBondContact N-O 3.27Å; L87-F166 PolarHBondContact O-N 3.04Å; L87-V180 HydrophobicContact CD2-CB 4.47Å; L87-V180 HydrophobicContact CD2-CG1 3.92Å; L87-V180 HydrophobicContact CD2-CG2 3.62Å
88Q98.6Very high91.7Very high28 Ų2844 Ų4413%0.13121%0.212CC..EExtended strand (participates in β ladder)trans-122.7130.9176-178.6-179.1-78.300110.2I47 S48 Y86 W129 V164 R165I47-Q88 WeakPolarHBondContact CA-O 3.1Å; S48-Q88 PolarHBondContact N-O 3.33Å; S48-Q88 PolarHBondContact O-N 2.84Å; S48-Q88 VanDerWaalsContact O-O 3.11Å; S48-Q88 PolarHBondContact OG-NE2 2.94Å; Y86-Q88 HydrophobicContact CD2-CB 4.04Å; Y86-Q88 HydrophobicContact CE2-CB 4.09Å; Q88-W129 HydrophobicContact CG-CH2 4.25Å; Q88-V164 WeakPolarHBondContact CA-O 3.31Å; Q88-R165 HydrophobicContact CB-CG 3.83Å; Q88-R165 HydrophobicContact CG-CG 3.93Å; Q88-R165 VanDerWaalsContact OE1-CZ 3.26Å
89V98.6Very high92.1Very high0 Ų041 Ų410%019%0.191CC..EExtended strand (participates in β ladder)trans-115.7126.1171.5-177.60000108.2M37 I42 L91 L163 V164 L182M37-V89 HydrophobicContact CE-CG2 3.95Å; M37-V89 HydrophobicContact SD-CB 4.48Å; M37-V89 HydrophobicContact SD-CG1 3.83Å; M37-V89 HydrophobicContact SD-CG2 3.74Å; I42-V89 HydrophobicContact CD1-CG1 3.82Å; I42-V89 HydrophobicContact CG2-CG1 4.13Å; V89-L91 HydrophobicContact CG1-CD2 3.95Å; V89-L163 WeakPolarHBondContact O-CA 3.41Å; V89-V164 PolarHBondContact N-O 2.7Å; V89-V164 PolarHBondContact O-N 3.18Å; V89-L182 HydrophobicContact CB-CD1 4.24Å; V89-L182 HydrophobicContact CG1-CD1 4.09Å; V89-L182 HydrophobicContact CG2-CD1 4.13Å
90D98.1Very high92.7Very high22 Ų2240.9 Ų40.912%0.11819%0.19CC..EExtended strand (participates in β ladder)trans-98123.5168.8-164-29.7000109.1D46 Q92 R162 L163D46-D90 HydrophobicContact CB-CB 4.26Å; D46-D90 PolarHBondContact O-N 2.78Å; D90-Q92 VanDerWaalsContact C-N 3.31Å; D90-Q92 WeakPolarHBondContact OD1-CA 3.23Å; D90-Q92 PolarHBondContact OD1-N 2.89Å; D90-R162 IonicContact OD1-CZ 2.66Å; D90-R162 IonicContact OD1-NH1 3.36Å; D90-R162 PolarHBondContact OD1-NH1 2.97Å; D90-R162 IonicContact OD1-NH2 2.86Å; D90-R162 IonicContact OD2-CZ 3.5Å; D90-R162 IonicContact OD2-NH1 3.15Å; D90-R162 PolarHBondContact OD2-NH1 3.1Å; D90-R162 IonicContact OD2-NH2 3.66Å; D90-R162 PolarHBondContact OD2-NH2 2.84Å; D90-L163 HydrophobicContact CB-CD2 4.4Å; D90-L163 HydrophobicContact CB-CG 4.47Å
91L96.6Very high93.5Very high16 Ų1637.7 Ų37.78%0.08418%0.176CC..EExtended strand (participates in β ladder)trans-91.53.8-179.8-56.1174000112.1L35 I42 V89 R93 H95 V97 R162 L182L35-L91 HydrophobicContact CB-CD2 4.3Å; L35-L91 HydrophobicContact CD1-CD1 3.95Å; L35-L91 HydrophobicContact CD1-CD2 4.36Å; I42-L91 HydrophobicContact CD1-CD2 3.69Å; V89-L91 HydrophobicContact CG1-CD2 3.95Å; L91-R93 PolarHBondContact O-N 3.26Å; L91-H95 WeakPolarHBondContact CB-ND1 3.45Å; L91-H95 HydrophobicContact CD1-CB 3.92Å; L91-H95 PolarHBondContact O-CE1 3.39Å; L91-V97 HydrophobicContact CD1-CG2 4.04Å; L91-R162 WeakPolarHBondContact CB-O 3.25Å; L91-R162 PolarHBondContact N-O 3.2Å; L91-L182 HydrophobicContact CD1-CD2 4.41Å; L91-L182 HydrophobicContact CD2-CD2 4.46Å
92Q93Very high94.6Very high103 Ų10333.5 Ų33.548%0.48115%0.149SC..EExtended strand (participates in β ladder)trans61.1-43.2-174.6-64.2-66.6-10.900115.6D46 D90 R162D46-Q92 PolarHBondContact OD1-NE2 2.83Å; D46-Q92 VanDerWaalsContact OD2-CG 3.26Å; D46-Q92 WeakPolarHBondContact OD2-CG 3.41Å; D46-Q92 PolarHBondContact OD2-NE2 3.01Å; D90-Q92 VanDerWaalsContact C-N 3.31Å; D90-Q92 WeakPolarHBondContact OD1-CA 3.23Å; D90-Q92 PolarHBondContact OD1-N 2.89Å; Q92-R162 WeakPolarHBondContact O-CD 3.13Å
93R92.6Very high95.5Very high140 Ų14027.7 Ų27.753%0.52812%0.124SC..EExtended strand (participates in β ladder)trans-112.3160.5177.9-60.3175.468.71740.4109.8L91 H95L91-R93 PolarHBondContact O-N 3.26Å; R93-H95 PolarHBondContact O-N 3.5Å; R93-H95 PolarHBondContact O-ND1 2.87Å
94L94.9Very high95.9Very high18 Ų1826.1 Ų26.19%0.09412%0.116CC..EExtended strand (participates in β ladder)trans-64.2132.2170-65.1166.5000109.7R124 A161 R162 W187 L192 D275L94-R124 HydrophobicContact CD2-CB 3.81Å; L94-R124 HydrophobicContact CD2-CG 3.7Å; L94-A161 WeakPolarHBondContact CA-O 3.45Å; L94-R162 HydrophobicContact CD2-CB 4.11Å; L94-W187 HydrophobicContact CB-CB 3.67Å; L94-W187 HydrophobicContact CB-CG 4.16Å; L94-W187 VanDerWaalsContact O-CB 3.29Å; L94-W187 WeakPolarHBondContact O-CB 3.29Å; L94-W187 PolarHBondContact O-N 2.83Å; L94-L192 HydrophobicContact CD1-CD2 3.73Å; L94-L192 HydrophobicContact CD2-CD2 4.43Å; L94-D275 HydrophobicContact CD1-CB 3.96Å
95H95.1Very high96Very high26 Ų2623.3 Ų23.312%0.1210%0.101CC..EExtended strand (participates in β ladder)trans-129.6149173.3-69.580.6000108.9L35 L91 R93 V160 A161 C185L35-H95 HydrophobicContact CD1-CB 4.14Å; L91-H95 WeakPolarHBondContact CB-ND1 3.45Å; L91-H95 HydrophobicContact CD1-CB 3.92Å; L91-H95 PolarHBondContact O-CE1 3.39Å; R93-H95 PolarHBondContact O-N 3.5Å; R93-H95 PolarHBondContact O-ND1 2.87Å; H95-V160 WeakPolarHBondContact O-CA 2.99Å; H95-A161 PolarHBondContact N-O 3.44Å; H95-A161 PolarHBondContact O-N 2.91Å; H95-C185 CarbonylContact C-O 3.43Å; H95-C185 WeakPolarHBondContact CA-O 3.47Å; H95-C185 WeakPolarHBondContact CB-O 3.3Å
96L95Very high95.6Very high3 Ų324.2 Ų24.22%0.01611%0.106CC..EExtended strand (participates in β ladder)trans-81.6120.1157.7-171.984.9000107F26 C31 P158 V160 G184 C185 W187F26-L96 HydrophobicContact CD2-CD2 3.52Å; F26-L96 HydrophobicContact CE2-CD1 3.93Å; F26-L96 HydrophobicContact CE2-CD2 3.42Å; F26-L96 VanDerWaalsContact CE2-CD2 3.42Å; F26-L96 HydrophobicContact CE2-CG 4.27Å; F26-L96 HydrophobicContact CZ-CD1 4.35Å; C31-L96 HydrophobicContact CB-CD2 4.35Å; L96-P158 HydrophobicContact CD1-CB 3.87Å; L96-P158 HydrophobicContact CD1-CG 4Å; L96-P158 HydrophobicContact CD2-CB 4.11Å; L96-P158 HydrophobicContact CD2-CG 4.32Å; L96-P158 HydrophobicContact CG-CB 3.96Å; L96-P158 HydrophobicContact CG-CG 4.44Å; L96-V160 HydrophobicContact CD1-CG2 3.69Å; L96-G184 CarbonylContact O-C 3.55Å; L96-G184 WeakPolarHBondContact O-CA 3.32Å; L96-C185 PolarHBondContact N-O 2.96Å; L96-C185 PolarHBondContact O-N 3.45Å; L96-C185 VanDerWaalsContact O-N 3.08Å; L96-W187 HydrophobicContact CB-CE3 4.23Å; L96-W187 HydrophobicContact CD1-CE3 4.48Å; L96-W187 HydrophobicContact CD1-CZ3 4.12Å
97V96.4Very high95.1Very high0 Ų023.2 Ų23.20%011%0.108CC..EExtended strand (participates in β ladder)trans-100.6113172-173.30000107.6L35 L91 L99 V100 L155 M159 V164 L182L35-V97 HydrophobicContact CD1-CG2 4.13Å; L91-V97 HydrophobicContact CD1-CG2 4.04Å; V97-L99 VanDerWaalsContact CG1-O 3.32Å; V97-L99 WeakPolarHBondContact CG1-O 3.21Å; V97-V100 HydrophobicContact CG1-CG1 4.24Å; V97-L155 HydrophobicContact CG1-CD1 4.05Å; V97-M159 HydrophobicContact CB-CE 3.84Å; V97-M159 HydrophobicContact CB-CG 3.95Å; V97-M159 HydrophobicContact CG1-CE 3.77Å; V97-M159 HydrophobicContact CG2-CE 4.34Å; V97-M159 PolarHBondContact N-O 2.68Å; V97-M159 PolarHBondContact O-N 3.31Å; V97-V164 HydrophobicContact CG2-CG2 4.32Å; V97-L182 HydrophobicContact CG1-CB 4.29Å; V97-L182 HydrophobicContact CG1-CD2 4.27Å; V97-L182 HydrophobicContact CG2-CD2 4.35Å
98A94.1Very high94.1Very high3 Ų326.5 Ų26.53%0.02514%0.142CC..EExtended strand (participates in β ladder)trans-105.4-19.5-175.700000112.9L155 P158 Y183A98-L155 WeakPolarHBondContact O-CB 3.41Å; A98-L155 PolarHBondContact O-N 2.87Å; A98-P158 HydrophobicContact CB-CB 4.32Å; A98-Y183 PolarHBondContact N-O 2.86Å
99L95.2Very high93.2Very high1 Ų127.6 Ų27.61%0.00516%0.161CC..EExtended strand (participates in β ladder)trans-141.3163.7167.7-38.258.6000110.6R32 V97 K153 Y183 A409R32-L99 HydrophobicContact CB-CD1 4.01Å; R32-L99 HydrophobicContact CG-CD1 3.75Å; R32-L99 VanDerWaalsContact CZ-CD1 3.45Å; V97-L99 VanDerWaalsContact CG1-O 3.32Å; V97-L99 WeakPolarHBondContact CG1-O 3.21Å; L99-K153 VanDerWaalsContact CA-O 3.23Å; L99-K153 WeakPolarHBondContact CA-O 3.37Å; L99-K153 WeakPolarHBondContact CB-O 3.21Å; L99-Y183 HydrophobicContact CB-CD2 4.12Å; L99-Y183 HydrophobicContact CB-CG 4.47Å; L99-Y183 HydrophobicContact CD2-CD2 4.39Å; L99-Y183 HydrophobicContact CD2-CG 4.43Å; L99-Y183 PolarHBondContact N-O 3.35Å; L99-Y183 PolarHBondContact O-N 3.43Å; L99-A409 HydrophobicContact CD2-CB 4.18Å
100V97.5Very high92.4Very high0 Ų034.4 Ų34.40%020%0.196CC..EExtended strand (participates in β ladder)trans-126.6150.2156.1-67.70000110.4V97 Y118 L120 K153 L155 F166 E181 L182V97-V100 HydrophobicContact CG1-CG1 4.24Å; V100-Y118 HydrophobicContact CG2-CE2 4.03Å; V100-Y118 VanDerWaalsContact CG2-OH 3.29Å; V100-Y118 WeakPolarHBondContact CG2-OH 3.17Å; V100-L120 HydrophobicContact CG1-CD1 4.11Å; V100-L120 HydrophobicContact CG1-CD2 4.49Å; V100-L120 HydrophobicContact CG2-CD1 3.99Å; V100-K153 HydrophobicContact CG2-CB 4.24Å; V100-K153 PolarHBondContact N-O 3Å; V100-K153 VanDerWaalsContact N-O 3.08Å; V100-K153 PolarHBondContact O-N 2.73Å; V100-L155 HydrophobicContact CG1-CD1 4.39Å; V100-F166 HydrophobicContact CB-CE1 3.79Å; V100-F166 HydrophobicContact CB-CZ 3.93Å; V100-F166 HydrophobicContact CG1-CE1 3.86Å; V100-F166 HydrophobicContact CG1-CZ 3.6Å; V100-F166 HydrophobicContact CG2-CE1 4.1Å; V100-E181 WeakPolarHBondContact CA-O 3.43Å; V100-L182 HydrophobicContact CG1-CG 4.34Å
101G96.9Very high91.7Very high0 Ų033.7 Ų33.70%019%0.194CC..EExtended strand (participates in β ladder)trans-109.2139.3166.100000110.1V151 V180 E181G101-V151 WeakPolarHBondContact CA-O 3.12Å; G101-V180 CarbonylContact O-C 3.44Å; G101-V180 VanDerWaalsContact O-CA 3.24Å; G101-V180 WeakPolarHBondContact O-CA 3.34Å; G101-E181 PolarHBondContact N-O 3.12Å; G101-E181 PolarHBondContact O-N 2.86Å
102T97.7Very high91.3Very high0 Ų040.4 Ų40.40%022%0.223CC..EExtended strand (participates in β ladder)trans-127.1150.6171.257.70000111.5Y118 N144 V151 F166 L178 R179 V180T102-Y118 HydrophobicContact CG2-CD1 4.12Å; T102-Y118 HydrophobicContact CG2-CE1 3.42Å; T102-Y118 VanDerWaalsContact CG2-CE1 3.42Å; T102-Y118 HydrophobicContact CG2-CE2 4.28Å; T102-Y118 WeakPolarHBondContact OG1-CE1 3.38Å; T102-N144 VanDerWaalsContact C-OD1 3.31Å; T102-N144 WeakPolarHBondContact CB-OD1 3.48Å; T102-N144 PolarHBondContact O-ND2 2.93Å; T102-N144 PolarHBondContact O-OD1 3.18Å; T102-N144 PolarHBondContact OG1-OD1 3.28Å; T102-V151 PolarHBondContact N-O 3.04Å; T102-V151 PolarHBondContact O-N 2.82Å; T102-F166 HydrophobicContact CG2-CD1 4.17Å; T102-F166 HydrophobicContact CG2-CE1 4.04Å; T102-L178 HydrophobicContact CG2-CD2 4Å; T102-R179 CarbonylContact C-O 3.47Å; T102-R179 WeakPolarHBondContact CA-O 3.38Å; T102-V180 HydrophobicContact CG2-CG1 4.15Å
103Q96.7Very high91.3Very high2 Ų237.7 Ų37.71%0.00921%0.21CC..EExtended strand (participates in β ladder)trans-148.7151.1-178.9-163.2-175.223.200109L64 E65 N144 E148 V150 R179L64-Q103 HydrophobicContact CD1-CB 3.65Å; E65-Q103 VanDerWaalsContact CD-NE2 3.34Å; E65-Q103 PolarHBondContact OE1-NE2 3.03Å; E65-Q103 PolarHBondContact OE2-NE2 3.41Å; Q103-N144 WeakPolarHBondContact CA-ND2 3.5Å; Q103-N144 PolarHBondContact N-OD1 2.88Å; Q103-E148 WeakPolarHBondContact CG-O 3.49Å; Q103-E148 PolarHBondContact NE2-O 2.82Å; Q103-V150 HydrophobicContact CB-CG2 4.31Å; Q103-V150 HydrophobicContact CG-CG2 4.05Å; Q103-R179 HydrophobicContact CB-CB 4.15Å; Q103-R179 VanDerWaalsContact CD-CZ 3.41Å; Q103-R179 PolarHBondContact N-O 3.07Å; Q103-R179 PolarHBondContact O-N 2.9Å
104G93.4Very high91.4Very high0 Ų032.1 Ų32.10%019%0.19CC..  trans-84.7-168.9178.300000114.3H106 P147 R179G104-H106 PolarHBondContact O-N 2.88Å; G104-P147 CarbonylContact C-O 3.58Å; G104-P147 WeakPolarHBondContact CA-O 3.34Å; G104-P147 PolarHBondContact N-O 2.7Å; G104-R179 VanDerWaalsContact O-CZ 3.27Å; G104-R179 PolarHBondContact O-NE 3.2Å; G104-R179 PolarHBondContact O-NH2 3.35Å
105R94.2Very high91.4Very high41 Ų4131.2 Ų31.216%0.15519%0.185CC..BIsolated β-bridgetrans-89.596.5174.7-167.9-177.381.298.7-6.7110.4D70 A72 A107 G111 E113 P147 C177D70-R105 VanDerWaalsContact O-CD 3.23Å; D70-R105 WeakPolarHBondContact O-CD 3.49Å; D70-R105 VanDerWaalsContact O-CG 3.26Å; D70-R105 WeakPolarHBondContact O-CG 3.38Å; D70-R105 PolarHBondContact O-NH1 2.95Å; A72-R105 HydrophobicContact CB-CB 3.59Å; A72-R105 HydrophobicContact CB-CG 3.67Å; R105-A107 HydrophobicContact CG-CB 4.2Å; R105-G111 CarbonylContact O-C 3.59Å; R105-G111 WeakPolarHBondContact O-CA 3.35Å; R105-E113 WeakPolarHBondContact CB-O 3.43Å; R105-E113 IonicContact CZ-OE1 2.91Å; R105-E113 IonicContact CZ-OE2 2.71Å; R105-E113 VanDerWaalsContact CZ-OE2 3.24Å; R105-E113 PolarHBondContact N-O 2.82Å; R105-E113 IonicContact NE-OE1 2.83Å; R105-E113 IonicContact NE-OE2 3.03Å; R105-E113 PolarHBondContact NE-OE2 3.35Å; R105-E113 VanDerWaalsContact NH2-CD 3.28Å; R105-E113 IonicContact NH2-OE1 2.9Å; R105-E113 PolarHBondContact NH2-OE1 3.3Å; R105-E113 IonicContact NH2-OE2 3.3Å; R105-E113 PolarHBondContact NH2-OE2 3Å; R105-P147 WeakPolarHBondContact O-CB 3.32Å; R105-C177 HydrophobicContact CB-CB 3.86Å
106H87.6Confident91.2Very high55 Ų5533.9 Ų33.926%0.25519%0.194SC..  trans-76.3-41.8179.1174.689.1000112.6G104 G108 G109 L110 G111 E148G104-H106 PolarHBondContact O-N 2.88Å; H106-G108 PolarHBondContact CD2-N 2.72Å; H106-G108 PolarHBondContact O-N 3.41Å; H106-G109 PolarHBondContact CD2-N 2.78Å; H106-G109 PolarHBondContact NE2-N 2.84Å; H106-G109 PolarHBondContact O-N 2.92Å; H106-L110 PolarHBondContact O-N 3.44Å; H106-G111 PolarHBondContact O-N 2.81Å; H106-E148 IonicContact CE1-OE2 2.72Å; H106-E148 PolarHBondContact CE1-OE2 2.77Å; H106-E148 IonicContact ND1-OE2 3.85Å; H106-E148 PolarHBondContact ND1-OE2 2.8Å
107A85.3Confident91.3Very high29 Ų2934.7 Ų34.724%0.2420%0.2CC..G310 helixtrans45.153.8173.900000114.8D70 R105 G109 L110D70-A107 WeakPolarHBondContact O-CB 3.26Å; R105-A107 HydrophobicContact CG-CB 4.2Å; A107-G109 VanDerWaalsContact C-N 3.32Å; A107-G109 PolarHBondContact O-N 3.26Å; A107-L110 PolarHBondContact O-N 3.4Å
108G78.7Confident91.3Very high70 Ų7034.7 Ų34.772%0.72220%0.2SC*.G310 helixtrans62.832.1-179.200000114.7H106 L110H106-G108 PolarHBondContact CD2-N 2.72Å; H106-G108 PolarHBondContact O-N 3.41Å; G108-L110 VanDerWaalsContact C-N 3.29Å; G108-L110 PolarHBondContact O-N 2.98Å
109G78.9Confident91.5Very high51 Ų5137.3 Ų37.353%0.52621%0.209SC..G310 helixtrans80.20.5-178.200000115.1H106 A107H106-G109 PolarHBondContact CD2-N 2.78Å; H106-G109 PolarHBondContact NE2-N 2.84Å; H106-G109 PolarHBondContact O-N 2.92Å; A107-G109 VanDerWaalsContact C-N 3.32Å; A107-G109 PolarHBondContact O-N 3.26Å
110L81.4Confident91.6Very high142 Ų14237.4 Ų37.474%0.74321%0.209SC*.THydrogen-bonded Turntrans-94.5-23178.2-62.8178.9000113.3H106 A107 G108H106-L110 PolarHBondContact O-N 3.44Å; A107-L110 PolarHBondContact O-N 3.4Å; G108-L110 VanDerWaalsContact C-N 3.29Å; G108-L110 PolarHBondContact O-N 2.98Å
111G83.9Confident91.6Very high7 Ų742.2 Ų42.27%0.07223%0.228CC..  trans-74.6149.2179.600000112.9R105 H106 P147R105-G111 CarbonylContact O-C 3.59Å; R105-G111 WeakPolarHBondContact O-CA 3.35Å; H106-G111 PolarHBondContact O-N 2.81Å; G111-P147 WeakPolarHBondContact O-CG 3.38Å
112K89.5Confident91.7Very high157 Ų15743.1 Ų43.168%0.68323%0.231SC*.  trans-141.52.7-169.1-65.2173.8-171.7165.20112.9F114K112-F114 WeakPolarHBondContact O-CD1 3.31Å
113E92.1Very high91.7Very high47 Ų4743.1 Ų43.122%0.2223%0.231CC..BIsolated β-bridgetrans-105.5125.6-168.7-5384.1170.400110.4R105 C177R105-E113 WeakPolarHBondContact CB-O 3.43Å; R105-E113 IonicContact CZ-OE1 2.91Å; R105-E113 IonicContact CZ-OE2 2.71Å; R105-E113 VanDerWaalsContact CZ-OE2 3.24Å; R105-E113 PolarHBondContact N-O 2.82Å; R105-E113 IonicContact NE-OE1 2.83Å; R105-E113 IonicContact NE-OE2 3.03Å; R105-E113 PolarHBondContact NE-OE2 3.35Å; R105-E113 VanDerWaalsContact NH2-CD 3.28Å; R105-E113 IonicContact NH2-OE1 2.9Å; R105-E113 PolarHBondContact NH2-OE1 3.3Å; R105-E113 IonicContact NH2-OE2 3.3Å; R105-E113 PolarHBondContact NH2-OE2 3Å; E113-C177 HydrophobicContact CB-CB 4.26Å; E113-C177 VanDerWaalsContact CB-SG 3.54Å
114F94.6Very high91.7Very high22 Ų2244 Ų4410%0.09623%0.234CC..  trans-157.8158.5-17556.8-90.1000111.3K112 R116 N144 E145 P147K112-F114 WeakPolarHBondContact O-CD1 3.31Å; F114-R116 HydrophobicContact CD2-CG 3.99Å; F114-R116 HydrophobicContact CE2-CG 3.58Å; F114-N144 HydrophobicContact CB-CB 4.32Å; F114-N144 HydrophobicContact CD2-CB 4.16Å; F114-N144 WeakPolarHBondContact CD2-O 3.4Å; F114-N144 VanDerWaalsContact CE2-O 3.23Å; F114-N144 WeakPolarHBondContact CE2-O 3.42Å; F114-E145 VanDerWaalsContact CE2-O 3.3Å; F114-E145 WeakPolarHBondContact CE2-O 3.29Å; F114-E145 VanDerWaalsContact CZ-C 3.45Å; F114-E145 WeakPolarHBondContact CZ-O 3.33Å; F114-P147 HydrophobicContact CD1-CG 4.01Å; F114-P147 HydrophobicContact CE1-CG 4.4Å
115S94.3Very high91.5Very high0 Ų048.2 Ų48.20%026%0.257CS..  trans-95.8104.4179.6-600000111.1S117 N144 P168 C177 L178S115-S117 PolarHBondContact O-N 3.17Å; S115-N144 PolarHBondContact O-N 2.86Å; S115-P168 WeakPolarHBondContact OG-CB 3.48Å; S115-C177 PolarHBondContact N-O 3.1Å; S115-C177 PolarHBondContact OG-O 2.87Å; S115-C177 VanDerWaalsContact OG-O 3.1Å; S115-L178 WeakPolarHBondContact OG-CG 3.1Å
116R92.7Very high91.4Very high82 Ų8247.8 Ų47.831%0.30927%0.265SS..SBendtrans-62.8-24.9176.2-74.3169.5164.5-82.7-22114.1F114 G143 N144 E145F114-R116 HydrophobicContact CD2-CG 3.99Å; F114-R116 HydrophobicContact CE2-CG 3.58Å; R116-G143 PolarHBondContact O-N 2.82Å; R116-N144 WeakPolarHBondContact CA-O 3.49Å; R116-E145 IonicContact CZ-OE2 2.79Å; R116-E145 IonicContact NH1-OE1 3.19Å; R116-E145 PolarHBondContact NH1-OE1 3.32Å; R116-E145 IonicContact NH1-OE2 3.37Å; R116-E145 PolarHBondContact NH1-OE2 2.97Å; R116-E145 IonicContact NH2-OE2 3.16Å; R116-E145 PolarHBondContact NH2-OE2 3.42Å
117S95.4Very high91.5Very high19 Ų1955.7 Ų55.713%0.13329%0.293CS..EExtended strand (participates in β ladder)trans-153.1165.7172.357.70000110.1S115 I141 R169S115-S117 PolarHBondContact O-N 3.17Å; S117-I141 CarbonylContact C-O 3.54Å; S117-I141 WeakPolarHBondContact CA-O 3.2Å; S117-I141 VanDerWaalsContact CB-O 3.24Å; S117-I141 WeakPolarHBondContact CB-O 3.46Å; S117-R169 WeakPolarHBondContact O-CA 3.1Å; S117-R169 WeakPolarHBondContact O-CB 3.47Å; S117-R169 PolarHBondContact O-N 2.8Å; S117-R169 WeakPolarHBondContact OG-CB 3.05Å; S117-R169 PolarHBondContact OG-O 3.15Å
118Y96.7Very high91.9Very high0 Ų057.9 Ų57.90%030%0.295CS..EExtended strand (participates in β ladder)trans-153.3170.9172.953.4-86.2000110.4V100 T102 L120 I141 F166 Y167V100-Y118 HydrophobicContact CG2-CE2 4.03Å; V100-Y118 VanDerWaalsContact CG2-OH 3.29Å; V100-Y118 WeakPolarHBondContact CG2-OH 3.17Å; T102-Y118 HydrophobicContact CG2-CD1 4.12Å; T102-Y118 HydrophobicContact CG2-CE1 3.42Å; T102-Y118 VanDerWaalsContact CG2-CE1 3.42Å; T102-Y118 HydrophobicContact CG2-CE2 4.28Å; T102-Y118 WeakPolarHBondContact OG1-CE1 3.38Å; Y118-L120 HydrophobicContact CD2-CD2 4.28Å; Y118-L120 HydrophobicContact CD2-CG 4.28Å; Y118-L120 HydrophobicContact CE2-CD2 4.21Å; Y118-L120 HydrophobicContact CE2-CG 4.15Å; Y118-I141 HydrophobicContact CD1-CG2 4.49Å; Y118-I141 HydrophobicContact CD2-CB 4.11Å; Y118-I141 HydrophobicContact CD2-CD1 4.12Å; Y118-I141 HydrophobicContact CD2-CG2 4.38Å; Y118-I141 HydrophobicContact CE1-CB 4.41Å; Y118-I141 HydrophobicContact CE1-CG2 3.82Å; Y118-I141 HydrophobicContact CE2-CB 3.84Å; Y118-I141 HydrophobicContact CE2-CD1 3.63Å; Y118-I141 HydrophobicContact CE2-CG1 4.35Å; Y118-I141 HydrophobicContact CE2-CG2 3.69Å; Y118-I141 PolarHBondContact N-O 3.12Å; Y118-I141 PolarHBondContact O-N 3.44Å; Y118-I141 WeakPolarHBondContact OH-CG2 3.29Å; Y118-F166 HydrophobicContact CD2-CD1 4.14Å; Y118-F166 HydrophobicContact CE2-CD1 4.12Å; Y118-F166 HydrophobicContact CE2-CE1 4.36Å; Y118-Y167 CarbonylContact C-O 3.58Å; Y118-Y167 WeakPolarHBondContact CA-O 3.48Å; Y118-Y167 WeakPolarHBondContact CB-O 3.5Å
119R97.8Very high92.7Very high59 Ų5956.9 Ų56.922%0.22327%0.269CS..EExtended strand (participates in β ladder)trans-118.1153.4160.2-64.8-172-160.471.9-4.8109.6E83 E139 V140 Y167E83-R119 IonicContact OE2-CZ 3.85Å; E83-R119 IonicContact OE2-NH1 2.95Å; E83-R119 PolarHBondContact OE2-NH1 2.79Å; E83-R119 IonicContact OE2-NH2 3.76Å; E83-R119 PolarHBondContact OE2-NH2 3.42Å; R119-E139 HydrophobicContact CG-CB 4.42Å; R119-E139 IonicContact NE-OE2 3.42Å; R119-V140 HydrophobicContact CG-CG2 4.09Å; R119-Y167 PolarHBondContact N-O 2.93Å; R119-Y167 PolarHBondContact O-N 3.01Å
120L98.3Very high93.6Very high2 Ų255 Ų551%0.0125%0.247CC..EExtended strand (participates in β ladder)trans-100.9137.9169.3-67.3172.7000110.3V100 Y118 W132 I141 L155 M159 V164 R165 F166V100-L120 HydrophobicContact CG1-CD1 4.11Å; V100-L120 HydrophobicContact CG1-CD2 4.49Å; V100-L120 HydrophobicContact CG2-CD1 3.99Å; Y118-L120 HydrophobicContact CD2-CD2 4.28Å; Y118-L120 HydrophobicContact CD2-CG 4.28Å; Y118-L120 HydrophobicContact CE2-CD2 4.21Å; Y118-L120 HydrophobicContact CE2-CG 4.15Å; L120-W132 HydrophobicContact CB-CB 3.92Å; L120-W132 PolarHBondContact O-N 2.84Å; L120-I141 HydrophobicContact CD1-CD1 3.65Å; L120-I141 HydrophobicContact CG-CD1 3.8Å; L120-L155 HydrophobicContact CD1-CD1 4Å; L120-L155 HydrophobicContact CD1-CD2 3.72Å; L120-M159 HydrophobicContact CD1-CE 4.04Å; L120-V164 HydrophobicContact CD2-CG1 4.04Å; L120-R165 WeakPolarHBondContact CA-O 3.37Å; L120-F166 HydrophobicContact CD2-CD1 3.58Å; L120-F166 HydrophobicContact CD2-CD2 4.31Å; L120-F166 HydrophobicContact CD2-CE1 3.72Å; L120-F166 HydrophobicContact CD2-CE2 4.41Å; L120-F166 HydrophobicContact CD2-CG 3.9Å; L120-F166 HydrophobicContact CD2-CZ 4.14Å
121R98.4Very high94.3Very high102 Ų10250 Ų5039%0.38523%0.229SC..EExtended strand (participates in β ladder)trans-122.9147.7160.2-58.1-168.474130.1-0.5109.1W129 M130 V164 R165 Y167R121-W129 HydrophobicContact CB-CE3 4.12Å; R121-W129 PolarHBondContact NH2-O 2.86Å; R121-M130 CarbonylContact C-O 3.52Å; R121-M130 WeakPolarHBondContact CA-O 3.25Å; R121-M130 VanDerWaalsContact CB-O 3.27Å; R121-M130 WeakPolarHBondContact CB-O 3.49Å; R121-V164 CarbonylContact O-C 3.51Å; R121-R165 HydrophobicContact CB-CB 4.4Å; R121-R165 PolarHBondContact N-O 3.27Å; R121-R165 PolarHBondContact O-N 2.97Å; R121-Y167 HydrophobicContact CB-CD2 4.32Å; R121-Y167 HydrophobicContact CB-CE2 3.89Å; R121-Y167 VanDerWaalsContact CD-CE2 3.5Å; R121-Y167 HydrophobicContact CG-CD2 3.84Å; R121-Y167 HydrophobicContact CG-CE2 3.62Å
122Y98.4Very high95Very high18 Ų1850 Ų507%0.07123%0.227CC..EExtended strand (participates in β ladder)trans-139.4160.6-178.463.2-81.9000111.9W129 M130 W132 M159 A161 L163 D216Y122-W129 WeakPolarHBondContact O-CA 3.29Å; Y122-M130 HydrophobicContact CD1-CB 4.49Å; Y122-M130 HydrophobicContact CD2-CE 3.91Å; Y122-M130 HydrophobicContact CE1-CB 4.07Å; Y122-M130 HydrophobicContact CE2-CB 4.17Å; Y122-M130 HydrophobicContact CE2-CE 3.81Å; Y122-M130 HydrophobicContact CE2-SD 4.26Å; Y122-M130 PolarHBondContact N-O 3.47Å; Y122-M130 PolarHBondContact O-N 2.73Å; Y122-W132 HydrophobicContact CD1-CB 4.15Å; Y122-W132 HydrophobicContact CE1-CB 3.98Å; Y122-M159 HydrophobicContact CD1-CB 4.11Å; Y122-M159 HydrophobicContact CD1-CG 4.42Å; Y122-M159 HydrophobicContact CD1-SD 3.54Å; Y122-M159 VanDerWaalsContact CD1-SD 3.54Å; Y122-M159 HydrophobicContact CD2-CB 4.12Å; Y122-M159 HydrophobicContact CE1-CB 4.05Å; Y122-M159 HydrophobicContact CE1-SD 4.25Å; Y122-M159 HydrophobicContact CE2-CB 4.05Å; Y122-M159 HydrophobicContact CG-CB 4.15Å; Y122-M159 HydrophobicContact CG-CG 4.38Å; Y122-M159 HydrophobicContact CG-SD 3.74Å; Y122-A161 HydrophobicContact CD2-CB 4.24Å; Y122-A161 HydrophobicContact CG-CB 4.44Å; Y122-L163 VanDerWaalsContact CA-O 3.32Å; Y122-L163 WeakPolarHBondContact CA-O 3.48Å; Y122-D216 VanDerWaalsContact OH-CB 3.3Å; Y122-D216 WeakPolarHBondContact OH-CB 3.45Å; Y122-D216 PolarHBondContact OH-OD2 3.01Å
123S97.6Very high95.2Very high0 Ų047.1 Ų47.10%022%0.215CC..EExtended strand (participates in β ladder)trans-148.4141.6-178.2-177.20000110.8D125 G126 R128 R162 L163S123-D125 PolarHBondContact OG-OD1 3.01Å; S123-D125 VanDerWaalsContact OG-OD1 3.11Å; S123-G126 WeakPolarHBondContact OG-CA 3.27Å; S123-G126 PolarHBondContact OG-N 3.49Å; S123-R128 WeakPolarHBondContact CA-O 3.46Å; S123-R128 WeakPolarHBondContact CB-O 3.5Å; S123-R128 PolarHBondContact OG-O 3.16Å; S123-R162 PolarHBondContact O-N 3.07Å; S123-L163 PolarHBondContact N-O 2.94Å; S123-L163 PolarHBondContact O-N 2.86Å
124R95.6Very high95.2Very high21 Ų2145.9 Ų45.98%0.07921%0.209CC..SBendtrans-94.3-32173-69.2-171.3-78.6-74.53.7112.2L94 V160 L192 D216L94-R124 HydrophobicContact CD2-CB 3.81Å; L94-R124 HydrophobicContact CD2-CG 3.7Å; R124-V160 WeakPolarHBondContact CD-O 3.39Å; R124-V160 WeakPolarHBondContact CG-O 3.37Å; R124-V160 PolarHBondContact NH1-O 3.24Å; R124-L192 HydrophobicContact CB-CD2 4.29Å; R124-L192 PolarHBondContact NE-O 3.33Å; R124-D216 IonicContact CZ-OD1 2.7Å; R124-D216 IonicContact CZ-OD2 3.31Å; R124-D216 VanDerWaalsContact CZ-OD2 3.25Å; R124-D216 IonicContact NH1-OD2 3.76Å; R124-D216 PolarHBondContact NH1-OD2 3.08Å; R124-D216 VanDerWaalsContact NH2-CG 3.28Å; R124-D216 IonicContact NH2-OD1 2.87Å; R124-D216 PolarHBondContact NH2-OD1 3.49Å; R124-D216 IonicContact NH2-OD2 3.3Å; R124-D216 PolarHBondContact NH2-OD2 3.07Å
125D90.1Very high95Very high88 Ų8845.7 Ų45.747%0.47121%0.208SC..SBendtrans-109-9.5-172.471.1-20.4000114.6S123 R127 R128S123-D125 PolarHBondContact OG-OD1 3.01Å; S123-D125 VanDerWaalsContact OG-OD1 3.11Å; D125-R127 VanDerWaalsContact C-N 3.29Å; D125-R127 PolarHBondContact O-N 2.83Å; D125-R127 PolarHBondContact OD1-N 3.28Å; D125-R127 WeakPolarHBondContact OD2-CB 3.42Å; D125-R128 PolarHBondContact OD1-N 2.71Å; D125-R128 PolarHBondContact OD2-N 2.99Å
126G91.3Very high94.9Very high32 Ų3251.1 Ų51.133%0.3323%0.228SC..SBendtrans81.1-2.7-173.200000115.2S123S123-G126 WeakPolarHBondContact OG-CA 3.27Å; S123-G126 PolarHBondContact OG-N 3.49Å
127R90.8Very high94.7Very high221 Ų22149.3 Ų49.383%0.83424%0.236SC*.SBendtrans-116-50.3-175.7-49.4177.4176.6-165.2-2.8111.4D125D125-R127 VanDerWaalsContact C-N 3.29Å; D125-R127 PolarHBondContact O-N 2.83Å; D125-R127 PolarHBondContact OD1-N 3.28Å; D125-R127 WeakPolarHBondContact OD2-CB 3.42Å
128R93.3Very high94.5Very high76 Ų7653.2 Ų53.229%0.28725%0.252SS..  trans-80.4118.9172.6-178.5-172.3177.482.20.8109.4S123 D125 M130 D216 G217 H218S123-R128 WeakPolarHBondContact CA-O 3.46Å; S123-R128 WeakPolarHBondContact CB-O 3.5Å; S123-R128 PolarHBondContact OG-O 3.16Å; D125-R128 PolarHBondContact OD1-N 2.71Å; D125-R128 PolarHBondContact OD2-N 2.99Å; R128-M130 HydrophobicContact CG-CE 4.49Å; R128-M130 HydrophobicContact CG-CG 4.25Å; R128-M130 HydrophobicContact CG-SD 4.33Å; R128-M130 PolarHBondContact NE-SD 3.25Å; R128-D216 PolarHBondContact NH2-O 3.25Å; R128-G217 VanDerWaalsContact NH2-C 3.29Å; R128-G217 PolarHBondContact NH2-O 2.77Å; R128-H218 PolarHBondContact NH1-CD2 3.33Å; R128-H218 PolarHBondContact NH1-NE2 3.09Å
129W96.1Very high94.3Very high48 Ų4856.6 Ų56.618%0.18227%0.268CS..  trans-110.8103.8176-75.890.9000111.2Q88 R121 Y122 L163 R165Q88-W129 HydrophobicContact CG-CH2 4.25Å; R121-W129 HydrophobicContact CB-CE3 4.12Å; R121-W129 PolarHBondContact NH2-O 2.86Å; Y122-W129 WeakPolarHBondContact O-CA 3.29Å; W129-L163 HydrophobicContact CH2-CB 3.56Å; W129-L163 HydrophobicContact CH2-CD2 4.3Å; W129-L163 HydrophobicContact CH2-CG 4.45Å; W129-L163 HydrophobicContact CZ2-CB 4.18Å; W129-L163 HydrophobicContact CZ2-CD2 4.19Å; W129-L163 HydrophobicContact CZ3-CB 4.3Å; W129-R165 HydrophobicContact CE3-CG 4.31Å; W129-R165 HydrophobicContact CH2-CG 3.62Å; W129-R165 VanDerWaalsContact CH2-NE 3.32Å; W129-R165 HydrophobicContact CZ3-CB 4Å; W129-R165 HydrophobicContact CZ3-CG 3.5Å
130M96.8Very high94.1Very high13 Ų1355.5 Ų55.56%0.06427%0.267CS..EExtended strand (participates in β ladder)trans-83147.8176.3-66.3145.1-58.500109.7R121 Y122 R128 D216R121-M130 CarbonylContact C-O 3.52Å; R121-M130 WeakPolarHBondContact CA-O 3.25Å; R121-M130 VanDerWaalsContact CB-O 3.27Å; R121-M130 WeakPolarHBondContact CB-O 3.49Å; Y122-M130 HydrophobicContact CD1-CB 4.49Å; Y122-M130 HydrophobicContact CD2-CE 3.91Å; Y122-M130 HydrophobicContact CE1-CB 4.07Å; Y122-M130 HydrophobicContact CE2-CB 4.17Å; Y122-M130 HydrophobicContact CE2-CE 3.81Å; Y122-M130 HydrophobicContact CE2-SD 4.26Å; Y122-M130 PolarHBondContact N-O 3.47Å; Y122-M130 PolarHBondContact O-N 2.73Å; R128-M130 HydrophobicContact CG-CE 4.49Å; R128-M130 HydrophobicContact CG-CG 4.25Å; R128-M130 HydrophobicContact CG-SD 4.33Å; R128-M130 PolarHBondContact NE-SD 3.25Å; M130-D216 HydrophobicContact CG-CB 4.4Å; M130-D216 HydrophobicContact SD-CB 3.95Å; M130-D216 VanDerWaalsContact SD-OD2 3.41Å
131G96.6Very high94Very high35 Ų3555.5 Ų55.536%0.36127%0.268SS..EExtended strand (participates in β ladder)trans-91.3133.7169.200000109.2
132W97.8Very high93.7Very high7 Ų755.3 Ų55.33%0.02728%0.282CS..PPolyproline II helixtrans-77.4142172.5-177.887.1000110.4L120 Y122 D134 I141 L155 P157L120-W132 HydrophobicContact CB-CB 3.92Å; L120-W132 PolarHBondContact O-N 2.84Å; Y122-W132 HydrophobicContact CD1-CB 4.15Å; Y122-W132 HydrophobicContact CE1-CB 3.98Å; W132-D134 HydrophobicContact CH2-CB 3.61Å; W132-D134 HydrophobicContact CZ2-CB 4.02Å; W132-D134 HydrophobicContact CZ3-CB 4.28Å; W132-I141 HydrophobicContact CE3-CD1 3.82Å; W132-I141 HydrophobicContact CE3-CG1 4.14Å; W132-I141 HydrophobicContact CH2-CG1 4.49Å; W132-I141 HydrophobicContact CZ3-CD1 3.69Å; W132-I141 HydrophobicContact CZ3-CG1 3.62Å; W132-L155 HydrophobicContact CD2-CD2 4.16Å; W132-L155 HydrophobicContact CE3-CD2 4.47Å; W132-L155 HydrophobicContact CH2-CD2 3.97Å; W132-L155 HydrophobicContact CZ2-CB 3.98Å; W132-L155 HydrophobicContact CZ2-CD2 3.66Å; W132-L155 HydrophobicContact CZ2-CG 4.43Å; W132-L155 HydrophobicContact CZ3-CD2 4.39Å; W132-P157 PolarHBondContact NE1-O 3.33Å
133K95.1Very high93.4Very high98 Ų9854.9 Ų54.943%0.42628%0.283SS..  trans-137.9150.7169.7-31.6-160.5-176.4-147.80107.6Q138 E139 P157K133-Q138 WeakPolarHBondContact CA-O 3.39Å; K133-E139 HydrophobicContact CD-CG 3.86Å; K133-E139 VanDerWaalsContact CE-OE1 3.29Å; K133-E139 WeakPolarHBondContact CE-OE1 3.45Å; K133-E139 HydrophobicContact CG-CG 4Å; K133-E139 IonicContact NZ-OE1 3.69Å; K133-E139 PolarHBondContact NZ-OE1 2.88Å; K133-P157 WeakPolarHBondContact O-CD 3.2Å
134D92.8Very high93.2Very high20 Ų2054.9 Ų54.911%0.10728%0.283CS..  trans-74.4174.7170.266.924.8000112.8W132 W136 G137 Q138 G156W132-D134 HydrophobicContact CH2-CB 3.61Å; W132-D134 HydrophobicContact CZ2-CB 4.02Å; W132-D134 HydrophobicContact CZ3-CB 4.28Å; D134-W136 HydrophobicContact CB-CE3 4.26Å; D134-W136 PolarHBondContact O-N 2.9Å; D134-W136 WeakPolarHBondContact OD1-CA 3Å; D134-W136 PolarHBondContact OD1-N 3.45Å; D134-G137 PolarHBondContact O-N 2.93Å; D134-G137 PolarHBondContact OD1-N 2.84Å; D134-Q138 PolarHBondContact N-O 2.93Å; D134-Q138 WeakPolarHBondContact OD1-CB 3.39Å; D134-Q138 PolarHBondContact OD1-N 2.96Å; D134-G156 CarbonylContact C-O 3.59Å; D134-G156 WeakPolarHBondContact CA-O 3.47Å; D134-G156 WeakPolarHBondContact CB-O 3.46Å
135R89.9Confident93Very high18 Ų1859.6 Ų59.67%0.06831%0.306CS..THydrogen-bonded Turntrans-57-15.5178-61-167.2-169.2-76.59.6114.5G156 D233 E246 Y253R135-G156 PolarHBondContact N-O 2.75Å; R135-D233 IonicContact CZ-OD2 2.82Å; R135-D233 IonicContact NH1-OD2 3.02Å; R135-D233 PolarHBondContact NH1-OD2 3.17Å; R135-D233 IonicContact NH2-OD2 2.73Å; R135-D233 PolarHBondContact NH2-OD2 2.74Å; R135-E246 IonicContact CZ-OE1 2.75Å; R135-E246 IonicContact NE-OE1 2.96Å; R135-E246 PolarHBondContact NE-OE1 2.82Å; R135-E246 IonicContact NE-OE2 3.18Å; R135-E246 IonicContact NH2-OE1 2.68Å; R135-E246 PolarHBondContact NH2-OE1 2.86Å; R135-Y253 WeakPolarHBondContact CB-OH 3.44Å; R135-Y253 WeakPolarHBondContact CD-OH 3.47Å; R135-Y253 VanDerWaalsContact CG-OH 3.32Å; R135-Y253 WeakPolarHBondContact CG-OH 3.4Å
136W91Very high93Very high114 Ų11458.8 Ų58.843%0.43230%0.301SS..THydrogen-bonded Turntrans-104.98.1177.3-47.2-71.9000112.7D134 L247 R248D134-W136 HydrophobicContact CB-CE3 4.26Å; D134-W136 PolarHBondContact O-N 2.9Å; D134-W136 WeakPolarHBondContact OD1-CA 3Å; D134-W136 PolarHBondContact OD1-N 3.45Å; W136-L247 WeakPolarHBondContact CZ2-O 3.34Å; W136-L247 PolarHBondContact NE1-O 2.92Å; W136-R248 VanDerWaalsContact CD2-NH2 3.32Å; W136-R248 VanDerWaalsContact CE2-NH2 3.32Å
137G89.8Confident92.9Very high45 Ų4558.4 Ų58.446%0.46429%0.293SS..  trans85.95.8174.300000115.3D134D134-G137 PolarHBondContact O-N 2.93Å; D134-G137 PolarHBondContact OD1-N 2.84Å
138Q91.3Very high92.9Very high101 Ų10153.7 Ų53.747%0.47228%0.28SS..  trans-80.7123.5-177.317064.519.600111.1K133 D134 V140K133-Q138 WeakPolarHBondContact CA-O 3.39Å; D134-Q138 PolarHBondContact N-O 2.93Å; D134-Q138 WeakPolarHBondContact OD1-CB 3.39Å; D134-Q138 PolarHBondContact OD1-N 2.96Å; Q138-V140 PolarHBondContact NE2-O 3.49Å
139E92Very high92.8Very high70 Ų7051.4 Ų51.433%0.32728%0.281SS..  trans-91.1-32.9-177.8-55-172.5169.100114.1R119 K133R119-E139 HydrophobicContact CG-CB 4.42Å; R119-E139 IonicContact NE-OE2 3.42Å; K133-E139 HydrophobicContact CD-CG 3.86Å; K133-E139 VanDerWaalsContact CE-OE1 3.29Å; K133-E139 WeakPolarHBondContact CE-OE1 3.45Å; K133-E139 HydrophobicContact CG-CG 4Å; K133-E139 IonicContact NZ-OE1 3.69Å; K133-E139 PolarHBondContact NZ-OE1 2.88Å
140V94Very high92.7Very high36 Ų3651.9 Ų51.922%0.21829%0.289CS..PPolyproline II helixtrans-86.9120.3-173.8-177.50000109.4R119 Q138R119-V140 HydrophobicContact CG-CG2 4.09Å; Q138-V140 PolarHBondContact NE2-O 3.49Å
141I95Very high92.6Very high3 Ų353.5 Ų53.52%0.01530%0.3CS..EExtended strand (participates in β ladder)trans-91.6132.6176-64.4166000108.7S117 Y118 L120 W132 K153 L155S117-I141 CarbonylContact C-O 3.54Å; S117-I141 WeakPolarHBondContact CA-O 3.2Å; S117-I141 VanDerWaalsContact CB-O 3.24Å; S117-I141 WeakPolarHBondContact CB-O 3.46Å; Y118-I141 HydrophobicContact CD1-CG2 4.49Å; Y118-I141 HydrophobicContact CD2-CB 4.11Å; Y118-I141 HydrophobicContact CD2-CD1 4.12Å; Y118-I141 HydrophobicContact CD2-CG2 4.38Å; Y118-I141 HydrophobicContact CE1-CB 4.41Å; Y118-I141 HydrophobicContact CE1-CG2 3.82Å; Y118-I141 HydrophobicContact CE2-CB 3.84Å; Y118-I141 HydrophobicContact CE2-CD1 3.63Å; Y118-I141 HydrophobicContact CE2-CG1 4.35Å; Y118-I141 HydrophobicContact CE2-CG2 3.69Å; Y118-I141 PolarHBondContact N-O 3.12Å; Y118-I141 PolarHBondContact O-N 3.44Å; Y118-I141 WeakPolarHBondContact OH-CG2 3.29Å; L120-I141 HydrophobicContact CD1-CD1 3.65Å; L120-I141 HydrophobicContact CG-CD1 3.8Å; W132-I141 HydrophobicContact CE3-CD1 3.82Å; W132-I141 HydrophobicContact CE3-CG1 4.14Å; W132-I141 HydrophobicContact CH2-CG1 4.49Å; W132-I141 HydrophobicContact CZ3-CD1 3.69Å; W132-I141 HydrophobicContact CZ3-CG1 3.62Å; I141-K153 HydrophobicContact CD1-CG 4.32Å; I141-K153 HydrophobicContact CG1-CG 4.34Å; I141-K153 HydrophobicContact CG2-CB 3.95Å; I141-K153 HydrophobicContact CG2-CD 4.02Å; I141-K153 HydrophobicContact CG2-CG 3.62Å; I141-L155 HydrophobicContact CD1-CD2 4.25Å
142S93.6Very high92.4Very high97 Ų9755.4 Ų55.468%0.67830%0.301SS*.EExtended strand (participates in β ladder)trans-68128.9167-550000110.1
143G92.1Very high92.3Very high9 Ų958 Ų589%0.09331%0.312CS..  trans-105.8-135.6177.700000111.6R116R116-G143 PolarHBondContact O-N 2.82Å
144N93.3Very high92.2Very high0 Ų057.3 Ų57.30%031%0.314CS..  trans-86.1146.3-170.6-56.288.1000112.9T102 Q103 F114 S115 R116 D146 G149T102-N144 VanDerWaalsContact C-OD1 3.31Å; T102-N144 WeakPolarHBondContact CB-OD1 3.48Å; T102-N144 PolarHBondContact O-ND2 2.93Å; T102-N144 PolarHBondContact O-OD1 3.18Å; T102-N144 PolarHBondContact OG1-OD1 3.28Å; Q103-N144 WeakPolarHBondContact CA-ND2 3.5Å; Q103-N144 PolarHBondContact N-OD1 2.88Å; F114-N144 HydrophobicContact CB-CB 4.32Å; F114-N144 HydrophobicContact CD2-CB 4.16Å; F114-N144 WeakPolarHBondContact CD2-O 3.4Å; F114-N144 VanDerWaalsContact CE2-O 3.23Å; F114-N144 WeakPolarHBondContact CE2-O 3.42Å; S115-N144 PolarHBondContact O-N 2.86Å; R116-N144 WeakPolarHBondContact CA-O 3.49Å; N144-D146 WeakPolarHBondContact CB-O 3.3Å; N144-G149 PolarHBondContact ND2-O 3.46Å
145E91.3Very high92.3Very high120 Ų12056.7 Ų56.756%0.56131%0.31SS*.SBendtrans-99.5-8.6169-76.5-62.6154.200113.4F114 R116F114-E145 VanDerWaalsContact CE2-O 3.3Å; F114-E145 WeakPolarHBondContact CE2-O 3.29Å; F114-E145 VanDerWaalsContact CZ-C 3.45Å; F114-E145 WeakPolarHBondContact CZ-O 3.33Å; R116-E145 IonicContact CZ-OE2 2.79Å; R116-E145 IonicContact NH1-OE1 3.19Å; R116-E145 PolarHBondContact NH1-OE1 3.32Å; R116-E145 IonicContact NH1-OE2 3.37Å; R116-E145 PolarHBondContact NH1-OE2 2.97Å; R116-E145 IonicContact NH2-OE2 3.16Å; R116-E145 PolarHBondContact NH2-OE2 3.42Å
146D90.3Very high92.4Very high72 Ų7257 Ų5739%0.38532%0.318SS..SBendtrans-147.3173.6177.373.578.5000111.8N144 E148 G149N144-D146 WeakPolarHBondContact CB-O 3.3Å; D146-E148 WeakPolarHBondContact OD1-CA 3.33Å; D146-E148 PolarHBondContact OD1-N 3.11Å; D146-G149 PolarHBondContact OD1-N 2.84Å
147P89.3Confident92.5Very high24 Ų2452.2 Ų52.216%0.15630%0.302CS..SBendtrans-82.7-10.2-175.3-9.126.9000116.1G104 R105 G111 F114 R179G104-P147 CarbonylContact C-O 3.58Å; G104-P147 WeakPolarHBondContact CA-O 3.34Å; G104-P147 PolarHBondContact N-O 2.7Å; R105-P147 WeakPolarHBondContact O-CB 3.32Å; G111-P147 WeakPolarHBondContact O-CG 3.38Å; F114-P147 HydrophobicContact CD1-CG 4.01Å; F114-P147 HydrophobicContact CE1-CG 4.4Å; P147-R179 PolarHBondContact O-NH2 3.08Å
148E90.2Very high92.8Very high121 Ų12150.9 Ų50.957%0.56529%0.285SS*.SBendtrans-112.9-45-165.6-173.2172.7148.800112.5Q103 H106 D146 V150Q103-E148 WeakPolarHBondContact CG-O 3.49Å; Q103-E148 PolarHBondContact NE2-O 2.82Å; H106-E148 IonicContact CE1-OE2 2.72Å; H106-E148 PolarHBondContact CE1-OE2 2.77Å; H106-E148 IonicContact ND1-OE2 3.85Å; H106-E148 PolarHBondContact ND1-OE2 2.8Å; D146-E148 WeakPolarHBondContact OD1-CA 3.33Å; D146-E148 PolarHBondContact OD1-N 3.11Å; E148-V150 PolarHBondContact O-N 2.94Å
149G90.1Very high93Very high29 Ų2946.1 Ų46.130%0.29926%0.263SS..  trans-64.5131-179.300000113N144 D146N144-G149 PolarHBondContact ND2-O 3.46Å; D146-G149 PolarHBondContact OD1-N 2.84Å
150V93.8Very high93.2Very high57 Ų5743.2 Ų43.235%0.34525%0.25SC..  trans-78.6125.2169.8175.60000109.4L64 E65 Q103 E148 L152L64-V150 HydrophobicContact CD1-CG1 4.27Å; L64-V150 HydrophobicContact CD1-CG2 4.19Å; L64-V150 HydrophobicContact CD2-CG1 4Å; L64-V150 HydrophobicContact CD2-CG2 4.08Å; L64-V150 HydrophobicContact CG-CG2 4.18Å; E65-V150 WeakPolarHBondContact OE1-CG2 3.2Å; Q103-V150 HydrophobicContact CB-CG2 4.31Å; Q103-V150 HydrophobicContact CG-CG2 4.05Å; E148-V150 PolarHBondContact O-N 2.94Å; V150-L152 HydrophobicContact CG1-CD2 4.03Å; V150-L152 HydrophobicContact CG1-CG 4.44Å
151V95Very high93.4Very high48 Ų4841.5 Ų41.529%0.29124%0.239SC..EExtended strand (participates in β ladder)trans-105.7117.3172.4173.90000108.8G101 T102G101-V151 WeakPolarHBondContact CA-O 3.12Å; T102-V151 PolarHBondContact N-O 3.04Å; T102-V151 PolarHBondContact O-N 2.82Å
152L93.6Very high93.4Very high74 Ų7444.2 Ų44.239%0.38725%0.25SC..EExtended strand (participates in β ladder)trans-89.9137.1172.8-60.8179.9000110.1V150 Y183 A409V150-L152 HydrophobicContact CG1-CD2 4.03Å; V150-L152 HydrophobicContact CG1-CG 4.44Å; L152-Y183 HydrophobicContact CD2-CD2 4.33Å; L152-Y183 HydrophobicContact CD2-CE2 3.56Å; L152-A409 HydrophobicContact CD1-CB 4.14Å
153K95.3Very high93.6Very high61 Ų6140 Ų4027%0.26522%0.219SC..EExtended strand (participates in β ladder)trans-122.3114.9171.3173.965.4176.5174.20109.7L99 V100 I141 L155L99-K153 VanDerWaalsContact CA-O 3.23Å; L99-K153 WeakPolarHBondContact CA-O 3.37Å; L99-K153 WeakPolarHBondContact CB-O 3.21Å; V100-K153 HydrophobicContact CG2-CB 4.24Å; V100-K153 PolarHBondContact N-O 3Å; V100-K153 VanDerWaalsContact N-O 3.08Å; V100-K153 PolarHBondContact O-N 2.73Å; I141-K153 HydrophobicContact CD1-CG 4.32Å; I141-K153 HydrophobicContact CG1-CG 4.34Å; I141-K153 HydrophobicContact CG2-CB 3.95Å; I141-K153 HydrophobicContact CG2-CD 4.02Å; I141-K153 HydrophobicContact CG2-CG 3.62Å; K153-L155 HydrophobicContact CG-CD2 4.13Å
154D92.7Very high94Very high85 Ų8539.6 Ų39.646%0.45522%0.215SC..EExtended strand (participates in β ladder)trans-62.9131.2162.4-83.7-80.4000110.9R32R32-D154 IonicContact CZ-OD1 3.71Å; R32-D154 IonicContact NH1-OD1 3.45Å; R32-D154 PolarHBondContact NH1-OD1 3.03Å; R32-D154 VanDerWaalsContact NH2-CG 3.33Å; R32-D154 IonicContact NH2-OD1 3.87Å; R32-D154 PolarHBondContact NH2-OD1 3.1Å; R32-D154 IonicContact NH2-OD2 2.74Å; R32-D154 PolarHBondContact NH2-OD2 2.88Å; R32-D154 VanDerWaalsContact NH2-OD2 3.16Å
155L94.6Very high94.2Very high7 Ų741.3 Ų41.34%0.03722%0.222CC..EExtended strand (participates in β ladder)trans-99.397.8175.2-56.7-179.2000108.4V97 A98 V100 L120 W132 I141 K153 P157 P158 M159V97-L155 HydrophobicContact CG1-CD1 4.05Å; A98-L155 WeakPolarHBondContact O-CB 3.41Å; A98-L155 PolarHBondContact O-N 2.87Å; V100-L155 HydrophobicContact CG1-CD1 4.39Å; L120-L155 HydrophobicContact CD1-CD1 4Å; L120-L155 HydrophobicContact CD1-CD2 3.72Å; W132-L155 HydrophobicContact CD2-CD2 4.16Å; W132-L155 HydrophobicContact CE3-CD2 4.47Å; W132-L155 HydrophobicContact CH2-CD2 3.97Å; W132-L155 HydrophobicContact CZ2-CB 3.98Å; W132-L155 HydrophobicContact CZ2-CD2 3.66Å; W132-L155 HydrophobicContact CZ2-CG 4.43Å; W132-L155 HydrophobicContact CZ3-CD2 4.39Å; I141-L155 HydrophobicContact CD1-CD2 4.25Å; K153-L155 HydrophobicContact CG-CD2 4.13Å; L155-P157 VanDerWaalsContact C-C 3.45Å; L155-P157 CarbonylContact C-O 3.54Å; L155-P157 VanDerWaalsContact C-O 3.26Å; L155-P157 CarbonylContact O-C 3.55Å; L155-P158 WeakPolarHBondContact O-CA 3.13Å; L155-M159 HydrophobicContact CD1-CE 3.76Å; L155-M159 HydrophobicContact CD1-CG 4.23Å; L155-M159 HydrophobicContact CD1-SD 4.26Å
156G92.1Very high94.6Very high23 Ų2335.6 Ų35.624%0.23720%0.195CC..EExtended strand (participates in β ladder)trans-110.6110.7166.200000109.2D134 R135D134-G156 CarbonylContact C-O 3.59Å; D134-G156 WeakPolarHBondContact CA-O 3.47Å; D134-G156 WeakPolarHBondContact CB-O 3.46Å; R135-G156 PolarHBondContact N-O 2.75Å
157P94.1Very high94.9Very high14 Ų1433.7 Ų33.79%0.09118%0.183CC..EExtended strand (participates in β ladder)cis-70.4156.4-2.733.2-37.7000112.9W132 K133 L155 T214W132-P157 PolarHBondContact NE1-O 3.33Å; K133-P157 WeakPolarHBondContact O-CD 3.2Å; L155-P157 VanDerWaalsContact C-C 3.45Å; L155-P157 CarbonylContact C-O 3.54Å; L155-P157 VanDerWaalsContact C-O 3.26Å; L155-P157 CarbonylContact O-C 3.55Å; P157-T214 HydrophobicContact CB-CG2 3.96Å; P157-T214 HydrophobicContact CG-CG2 3.74Å
158P94.6Very high95.2Very high17 Ų1732.6 Ų32.611%0.1118%0.176CC..EExtended strand (participates in β ladder)trans-69.7163.5168.731.9-35.9000110.4L96 A98 L155 D233L96-P158 HydrophobicContact CD1-CB 3.87Å; L96-P158 HydrophobicContact CD1-CG 4Å; L96-P158 HydrophobicContact CD2-CB 4.11Å; L96-P158 HydrophobicContact CD2-CG 4.32Å; L96-P158 HydrophobicContact CG-CB 3.96Å; L96-P158 HydrophobicContact CG-CG 4.44Å; A98-P158 HydrophobicContact CB-CB 4.32Å; L155-P158 WeakPolarHBondContact O-CA 3.13Å; P158-D233 HydrophobicContact CG-CB 4.48Å; P158-D233 VanDerWaalsContact CG-O 3.29Å; P158-D233 WeakPolarHBondContact CG-O 3.45Å
159M95.9Very high95.3Very high2 Ų230.2 Ų30.21%0.0116%0.161CC..EExtended strand (participates in β ladder)trans-121.1127.1-177.861.2-177.5-178.300112.8V97 L120 Y122 L155 A161 V164V97-M159 HydrophobicContact CB-CE 3.84Å; V97-M159 HydrophobicContact CB-CG 3.95Å; V97-M159 HydrophobicContact CG1-CE 3.77Å; V97-M159 HydrophobicContact CG2-CE 4.34Å; V97-M159 PolarHBondContact N-O 2.68Å; V97-M159 PolarHBondContact O-N 3.31Å; L120-M159 HydrophobicContact CD1-CE 4.04Å; Y122-M159 HydrophobicContact CD1-CB 4.11Å; Y122-M159 HydrophobicContact CD1-CG 4.42Å; Y122-M159 HydrophobicContact CD1-SD 3.54Å; Y122-M159 VanDerWaalsContact CD1-SD 3.54Å; Y122-M159 HydrophobicContact CD2-CB 4.12Å; Y122-M159 HydrophobicContact CE1-CB 4.05Å; Y122-M159 HydrophobicContact CE1-SD 4.25Å; Y122-M159 HydrophobicContact CE2-CB 4.05Å; Y122-M159 HydrophobicContact CG-CB 4.15Å; Y122-M159 HydrophobicContact CG-CG 4.38Å; Y122-M159 HydrophobicContact CG-SD 3.74Å; L155-M159 HydrophobicContact CD1-CE 3.76Å; L155-M159 HydrophobicContact CD1-CG 4.23Å; L155-M159 HydrophobicContact CD1-SD 4.26Å; M159-A161 PolarHBondContact O-N 3.31Å; M159-V164 HydrophobicContact CE-CB 4.43Å; M159-V164 HydrophobicContact CE-CG1 3.71Å; M159-V164 HydrophobicContact CE-CG2 3.77Å
160V96.6Very high95.1Very high8 Ų828.9 Ų28.95%0.04815%0.147CC..EExtended strand (participates in β ladder)trans-83.7109.9171-1780000109.1H95 L96 R124 W187 L228H95-V160 WeakPolarHBondContact O-CA 2.99Å; L96-V160 HydrophobicContact CD1-CG2 3.69Å; R124-V160 WeakPolarHBondContact CD-O 3.39Å; R124-V160 WeakPolarHBondContact CG-O 3.37Å; R124-V160 PolarHBondContact NH1-O 3.24Å; V160-W187 HydrophobicContact CG1-CB 4.44Å; V160-W187 HydrophobicContact CG1-CD2 3.77Å; V160-W187 HydrophobicContact CG1-CE3 4.36Å; V160-W187 HydrophobicContact CG1-CG 3.78Å; V160-W187 HydrophobicContact CG1-CZ2 4.48Å; V160-W187 HydrophobicContact CG2-CD2 4Å; V160-W187 HydrophobicContact CG2-CE3 3.83Å; V160-W187 HydrophobicContact CG2-CH2 3.8Å; V160-W187 HydrophobicContact CG2-CZ2 3.96Å; V160-W187 HydrophobicContact CG2-CZ3 3.73Å; V160-L228 HydrophobicContact CB-CD1 3.76Å; V160-L228 HydrophobicContact CG1-CD1 3.97Å; V160-L228 HydrophobicContact CG2-CD1 4Å
161A97.1Very high94.4Very high0 Ų028.9 Ų28.90%015%0.146CC..EExtended strand (participates in β ladder)trans-138.6150.9-168.800000112.7L94 H95 Y122 M159 V164L94-A161 WeakPolarHBondContact CA-O 3.45Å; H95-A161 PolarHBondContact N-O 3.44Å; H95-A161 PolarHBondContact O-N 2.91Å; Y122-A161 HydrophobicContact CD2-CB 4.24Å; Y122-A161 HydrophobicContact CG-CB 4.44Å; M159-A161 PolarHBondContact O-N 3.31Å; A161-V164 HydrophobicContact CB-CG2 3.88Å
162R96.4Very high93.6Very high60 Ų6029.1 Ų29.123%0.22614%0.141CC..EExtended strand (participates in β ladder)trans-104.4-41.2163.4-168.3-173.385.275.511.5110.5D90 L91 Q92 L94 S123D90-R162 IonicContact OD1-CZ 2.66Å; D90-R162 IonicContact OD1-NH1 3.36Å; D90-R162 PolarHBondContact OD1-NH1 2.97Å; D90-R162 IonicContact OD1-NH2 2.86Å; D90-R162 IonicContact OD2-CZ 3.5Å; D90-R162 IonicContact OD2-NH1 3.15Å; D90-R162 PolarHBondContact OD2-NH1 3.1Å; D90-R162 IonicContact OD2-NH2 3.66Å; D90-R162 PolarHBondContact OD2-NH2 2.84Å; L91-R162 WeakPolarHBondContact CB-O 3.25Å; L91-R162 PolarHBondContact N-O 3.2Å; Q92-R162 WeakPolarHBondContact O-CD 3.13Å; L94-R162 HydrophobicContact CD2-CB 4.11Å; S123-R162 PolarHBondContact O-N 3.07Å
163L98.3Very high93Very high9 Ų930.2 Ų30.25%0.04715%0.151CC..EExtended strand (participates in β ladder)trans-118142.3173.4-41.890.1000110.2V89 D90 Y122 S123 W129V89-L163 WeakPolarHBondContact O-CA 3.41Å; D90-L163 HydrophobicContact CB-CD2 4.4Å; D90-L163 HydrophobicContact CB-CG 4.47Å; Y122-L163 VanDerWaalsContact CA-O 3.32Å; Y122-L163 WeakPolarHBondContact CA-O 3.48Å; S123-L163 PolarHBondContact N-O 2.94Å; S123-L163 PolarHBondContact O-N 2.86Å; W129-L163 HydrophobicContact CH2-CB 3.56Å; W129-L163 HydrophobicContact CH2-CD2 4.3Å; W129-L163 HydrophobicContact CH2-CG 4.45Å; W129-L163 HydrophobicContact CZ2-CB 4.18Å; W129-L163 HydrophobicContact CZ2-CD2 4.19Å; W129-L163 HydrophobicContact CZ3-CB 4.3Å
164V98.6Very high92.3Very high0 Ų029.4 Ų29.40%015%0.149CC..EExtended strand (participates in β ladder)trans-126.9138.8175.8179.40000109Q88 V89 V97 L120 R121 M159 A161 F166 L182Q88-V164 WeakPolarHBondContact CA-O 3.31Å; V89-V164 PolarHBondContact N-O 2.7Å; V89-V164 PolarHBondContact O-N 3.18Å; V97-V164 HydrophobicContact CG2-CG2 4.32Å; L120-V164 HydrophobicContact CD2-CG1 4.04Å; R121-V164 CarbonylContact O-C 3.51Å; M159-V164 HydrophobicContact CE-CB 4.43Å; M159-V164 HydrophobicContact CE-CG1 3.71Å; M159-V164 HydrophobicContact CE-CG2 3.77Å; A161-V164 HydrophobicContact CB-CG2 3.88Å; V164-F166 HydrophobicContact CG1-CD2 4.41Å; V164-F166 HydrophobicContact CG1-CE2 4.06Å; V164-L182 HydrophobicContact CB-CD2 3.77Å; V164-L182 HydrophobicContact CG1-CD2 3.98Å; V164-L182 HydrophobicContact CG2-CD2 3.69Å
165R98.6Very high92Very high37 Ų3728.9 Ų28.914%0.1415%0.151CC..EExtended strand (participates in β ladder)trans-119.6125.7173.8-79.1177.3-175-169.2-1.9111.1Y86 L87 Q88 L120 R121 W129 Y167Y86-R165 HydrophobicContact CD2-CG 3.73Å; Y86-R165 HydrophobicContact CE2-CG 4.3Å; Y86-R165 HydrophobicContact CG-CG 4.26Å; Y86-R165 PolarHBondContact OH-NH2 3Å; L87-R165 CarbonylContact O-C 3.57Å; L87-R165 WeakPolarHBondContact O-CA 3.46Å; Q88-R165 HydrophobicContact CB-CG 3.83Å; Q88-R165 HydrophobicContact CG-CG 3.93Å; Q88-R165 VanDerWaalsContact OE1-CZ 3.26Å; L120-R165 WeakPolarHBondContact CA-O 3.37Å; R121-R165 HydrophobicContact CB-CB 4.4Å; R121-R165 PolarHBondContact N-O 3.27Å; R121-R165 PolarHBondContact O-N 2.97Å; W129-R165 HydrophobicContact CE3-CG 4.31Å; W129-R165 HydrophobicContact CH2-CG 3.62Å; W129-R165 VanDerWaalsContact CH2-NE 3.32Å; W129-R165 HydrophobicContact CZ3-CB 4Å; W129-R165 HydrophobicContact CZ3-CG 3.5Å; R165-Y167 HydrophobicContact CB-CD2 3.96Å; R165-Y167 HydrophobicContact CB-CE2 3.53Å; R165-Y167 WeakPolarHBondContact CD-OH 3.46Å; R165-Y167 HydrophobicContact CG-CE2 4.27Å; R165-Y167 PolarHBondContact NH1-OH 2.79Å; R165-Y167 VanDerWaalsContact NH1-OH 3.16Å
166F98.6Very high92Very high0 Ų028.8 Ų28.80%015%0.151CC..EExtended strand (participates in β ladder)trans-92.1110.7166.7-63.2-105000107.5Y86 L87 V100 T102 Y118 L120 V164 P168 L178 V180 L182Y86-F166 VanDerWaalsContact CA-O 3.25Å; Y86-F166 WeakPolarHBondContact CA-O 3.45Å; L87-F166 HydrophobicContact CB-CB 4.39Å; L87-F166 PolarHBondContact N-O 3.27Å; L87-F166 PolarHBondContact O-N 3.04Å; V100-F166 HydrophobicContact CB-CE1 3.79Å; V100-F166 HydrophobicContact CB-CZ 3.93Å; V100-F166 HydrophobicContact CG1-CE1 3.86Å; V100-F166 HydrophobicContact CG1-CZ 3.6Å; V100-F166 HydrophobicContact CG2-CE1 4.1Å; T102-F166 HydrophobicContact CG2-CD1 4.17Å; T102-F166 HydrophobicContact CG2-CE1 4.04Å; Y118-F166 HydrophobicContact CD2-CD1 4.14Å; Y118-F166 HydrophobicContact CE2-CD1 4.12Å; Y118-F166 HydrophobicContact CE2-CE1 4.36Å; L120-F166 HydrophobicContact CD2-CD1 3.58Å; L120-F166 HydrophobicContact CD2-CD2 4.31Å; L120-F166 HydrophobicContact CD2-CE1 3.72Å; L120-F166 HydrophobicContact CD2-CE2 4.41Å; L120-F166 HydrophobicContact CD2-CG 3.9Å; L120-F166 HydrophobicContact CD2-CZ 4.14Å; V164-F166 HydrophobicContact CG1-CD2 4.41Å; V164-F166 HydrophobicContact CG1-CE2 4.06Å; F166-P168 WeakPolarHBondContact O-CD 3.43Å; F166-L178 HydrophobicContact CB-CD1 3.91Å; F166-V180 HydrophobicContact CD1-CB 4.5Å; F166-V180 HydrophobicContact CD1-CG1 3.9Å; F166-V180 HydrophobicContact CD2-CG1 4.26Å; F166-V180 HydrophobicContact CD2-CG2 4.26Å; F166-V180 HydrophobicContact CE1-CB 4.05Å; F166-V180 HydrophobicContact CE1-CG1 3.93Å; F166-V180 HydrophobicContact CE2-CB 4.13Å; F166-V180 HydrophobicContact CE2-CG1 4.32Å; F166-V180 HydrophobicContact CE2-CG2 3.85Å; F166-V180 HydrophobicContact CG-CG1 4.07Å; F166-V180 HydrophobicContact CZ-CB 3.85Å; F166-V180 HydrophobicContact CZ-CG1 4.14Å; F166-V180 HydrophobicContact CZ-CG2 4.06Å; F166-L182 HydrophobicContact CE2-CD1 4.13Å; F166-L182 HydrophobicContact CE2-CD2 4.47Å; F166-L182 HydrophobicContact CE2-CG 4.28Å; F166-L182 HydrophobicContact CZ-CD1 4.33Å; F166-L182 HydrophobicContact CZ-CG 4.18Å
167Y97.9Very high92.2Very high32 Ų3227.8 Ų27.813%0.12514%0.14CC..EExtended strand (participates in β ladder)trans-90.695.2169.4-76-97000107.4E83 E85 Y86 Y118 R119 R121 R165E83-Y167 WeakPolarHBondContact O-CD1 3.5Å; E85-Y167 VanDerWaalsContact O-CD1 3.3Å; E85-Y167 WeakPolarHBondContact O-CD1 3.24Å; Y86-Y167 HydrophobicContact CD1-CD1 4.48Å; Y86-Y167 AromaticContact CD1-CE1 3.64Å; Y86-Y167 HydrophobicContact CD1-CE1 3.64Å; Y86-Y167 AromaticContact CD1-CZ 3.7Å; Y86-Y167 HydrophobicContact CG-CE1 4.05Å; Y86-Y167 HydrophobicContact CG-CE2 4.38Å; Y86-Y167 AromaticContact CG-CZ 3.89Å; Y118-Y167 CarbonylContact C-O 3.58Å; Y118-Y167 WeakPolarHBondContact CA-O 3.48Å; Y118-Y167 WeakPolarHBondContact CB-O 3.5Å; R119-Y167 PolarHBondContact N-O 2.93Å; R119-Y167 PolarHBondContact O-N 3.01Å; R121-Y167 HydrophobicContact CB-CD2 4.32Å; R121-Y167 HydrophobicContact CB-CE2 3.89Å; R121-Y167 VanDerWaalsContact CD-CE2 3.5Å; R121-Y167 HydrophobicContact CG-CD2 3.84Å; R121-Y167 HydrophobicContact CG-CE2 3.62Å; R165-Y167 HydrophobicContact CB-CD2 3.96Å; R165-Y167 HydrophobicContact CB-CE2 3.53Å; R165-Y167 WeakPolarHBondContact CD-OH 3.46Å; R165-Y167 HydrophobicContact CG-CE2 4.27Å; R165-Y167 PolarHBondContact NH1-OH 2.79Å; R165-Y167 VanDerWaalsContact NH1-OH 3.16Å
168P96.2Very high92.3Very high1 Ų127.1 Ų27.11%0.00614%0.136CC..EExtended strand (participates in β ladder)trans-55.3149.4173.827-37.2000109.8W73 P75 V79 E85 S115 F166 V176 L178W73-P168 HydrophobicContact CH2-CG 3.94Å; W73-P168 HydrophobicContact CZ3-CG 3.95Å; P75-P168 HydrophobicContact CG-CG 4.34Å; V79-P168 WeakPolarHBondContact CG1-O 3.46Å; V79-P168 HydrophobicContact CG2-CG 4.25Å; E85-P168 WeakPolarHBondContact O-CD 3.37Å; S115-P168 WeakPolarHBondContact OG-CB 3.48Å; F166-P168 WeakPolarHBondContact O-CD 3.43Å; P168-V176 HydrophobicContact CB-CG2 4.05Å; P168-V176 HydrophobicContact CG-CG2 4.42Å; P168-L178 HydrophobicContact CB-CD1 4.04Å
169R92Very high92.5Very high70 Ų7026.9 Ų26.926%0.26413%0.133SC..EExtended strand (participates in β ladder)trans-132.9128.1-176.5-177.1175-165.3-84.9-25111.4E83 S117E83-R169 VanDerWaalsContact CD-NE 3.28Å; E83-R169 HydrophobicContact CG-CG 4.36Å; E83-R169 IonicContact OE1-CZ 2.71Å; E83-R169 IonicContact OE1-NE 3.22Å; E83-R169 PolarHBondContact OE1-NE 2.91Å; E83-R169 IonicContact OE1-NH2 3.18Å; E83-R169 PolarHBondContact OE1-NH2 3.26Å; E83-R169 IonicContact OE2-NE 3.57Å; E83-R169 PolarHBondContact OE2-NE 2.8Å; E83-R169 VanDerWaalsContact OE2-NE 3.16Å; S117-R169 WeakPolarHBondContact O-CA 3.1Å; S117-R169 WeakPolarHBondContact O-CB 3.47Å; S117-R169 PolarHBondContact O-N 2.8Å; S117-R169 WeakPolarHBondContact OG-CB 3.05Å; S117-R169 PolarHBondContact OG-O 3.15Å
170A85Confident92.6Very high1 Ų126.8 Ų26.81%0.00813%0.132CC..  trans-121.2132.6178.600000110.3V79 F80 R172 M174 V176V79-A170 HydrophobicContact CB-CB 4.43Å; F80-A170 HydrophobicContact CB-CB 4.43Å; A170-R172 WeakPolarHBondContact CB-O 3.5Å; A170-R172 PolarHBondContact O-N 3.15Å; A170-M174 HydrophobicContact CB-CG 3.99Å; A170-V176 HydrophobicContact CB-CG1 3.93Å
171D79.3Confident92.7Very high58 Ų5826.4 Ų26.431%0.3113%0.13SC..SBendtrans-81.90.3177.872-50.7000113.4K634D171-K634 VanDerWaalsContact OD2-CE 3.23Å; D171-K634 WeakPolarHBondContact OD2-CE 3.46Å; D171-K634 IonicContact OD2-NZ 3.81Å; D171-K634 PolarHBondContact OD2-NZ 3.4Å
172R77.7Confident92.7Very high52 Ų5226.4 Ų26.420%0.19613%0.13CC..SBendtrans-163168.7-173.858.9-166.3144.8175.5-2.3109.2F80 A170 M174 N630F80-R172 VanDerWaalsContact CB-O 3.3Å; F80-R172 WeakPolarHBondContact CB-O 3.36Å; A170-R172 WeakPolarHBondContact CB-O 3.5Å; A170-R172 PolarHBondContact O-N 3.15Å; R172-M174 HydrophobicContact CG-CB 4.36Å; R172-M174 HydrophobicContact CG-CG 4.05Å; R172-M174 HydrophobicContact CG-SD 4.1Å; R172-M174 PolarHBondContact O-N 3.17Å; R172-N630 WeakPolarHBondContact CD-OD1 3.46Å; R172-N630 PolarHBondContact NH1-ND2 3.31Å; R172-N630 PolarHBondContact NH1-OD1 3.24Å
173V81.6Confident92.7Very high97 Ų9724.4 Ų24.459%0.58812%0.123SC*.SBendtrans-67.6104.9167.5179.40000108.3F80F80-V173 HydrophobicContact CD1-CG2 3.82Å
174M80.2Confident92.5Very high45 Ų4524 Ų2422%0.22212%0.12CC..  trans-146.4146.2170.556178.7-75.600108.4A170 R172 V176A170-M174 HydrophobicContact CB-CG 3.99Å; R172-M174 HydrophobicContact CG-CB 4.36Å; R172-M174 HydrophobicContact CG-CG 4.05Å; R172-M174 HydrophobicContact CG-SD 4.1Å; R172-M174 PolarHBondContact O-N 3.17Å; M174-V176 HydrophobicContact CE-CG1 4.09Å; M174-V176 HydrophobicContact CG-CG1 4.09Å; M174-V176 PolarHBondContact O-N 2.81Å
175S87.1Confident92.1Very high73 Ų7325.5 Ų25.551%0.5113%0.131SC..  trans-65.2119169-56.20000108.5
176V93.4Very high91.8Very high5 Ų525.9 Ų25.93%0.0314%0.136CC..  trans-109.6143.8172.6-66.60000108.5P75 V79 P168 A170 M174P75-V176 WeakPolarHBondContact CD-O 3.47Å; P75-V176 HydrophobicContact CG-CG2 4.49Å; V79-V176 HydrophobicContact CB-CG2 4.12Å; V79-V176 HydrophobicContact CG2-CG2 3.41Å; V79-V176 VanDerWaalsContact CG2-CG2 3.41Å; P168-V176 HydrophobicContact CB-CG2 4.05Å; P168-V176 HydrophobicContact CG-CG2 4.42Å; A170-V176 HydrophobicContact CB-CG1 3.93Å; M174-V176 HydrophobicContact CE-CG1 4.09Å; M174-V176 HydrophobicContact CG-CG1 4.09Å; M174-V176 PolarHBondContact O-N 2.81Å
177C96.4Very high91.6Very high2 Ų226.5 Ų26.51%0.01414%0.138CC..  trans-134.7159.8174.4-580000108.7A72 W73 C74 R105 E113 S115A72-C177 HydrophobicContact CB-CB 3.78Å; W73-C177 CarbonylContact O-C 3.58Å; W73-C177 WeakPolarHBondContact O-CA 3.28Å; W73-C177 VanDerWaalsContact O-CB 3.23Å; W73-C177 WeakPolarHBondContact O-CB 3.46Å; C74-C177 HydrophobicContact CB-CB 4.11Å; C74-C177 WeakPolarHBondContact CB-SG 3.09Å; C74-C177 WeakPolarHBondContact SG-CB 3.42Å; C74-C177 CovalentContact SG-SG 2.04Å; C74-C177 PolarHBondContact SG-SG 2.81Å; R105-C177 HydrophobicContact CB-CB 3.86Å; E113-C177 HydrophobicContact CB-CB 4.26Å; E113-C177 VanDerWaalsContact CB-SG 3.54Å; S115-C177 PolarHBondContact N-O 3.1Å; S115-C177 PolarHBondContact OG-O 2.87Å; S115-C177 VanDerWaalsContact OG-O 3.1Å
178L97.3Very high91.2Very high0 Ų034.3 Ų34.30%017%0.167CC..BIsolated β-bridgetrans-137.5133.1174.3-80.3174.4000110.9S62 W73 T102 S115 F166 P168 V180S62-L178 WeakPolarHBondContact CA-O 3.42Å; W73-L178 HydrophobicContact CE3-CB 4.1Å; W73-L178 HydrophobicContact CZ3-CB 4.4Å; W73-L178 HydrophobicContact CZ3-CD1 4.31Å; W73-L178 PolarHBondContact N-O 2.9Å; W73-L178 PolarHBondContact O-N 3.25Å; T102-L178 HydrophobicContact CG2-CD2 4Å; S115-L178 WeakPolarHBondContact OG-CG 3.1Å; F166-L178 HydrophobicContact CB-CD1 3.91Å; P168-L178 HydrophobicContact CB-CD1 4.04Å; L178-V180 HydrophobicContact CB-CG1 4.02Å; L178-V180 HydrophobicContact CD1-CG1 4.31Å; L178-V180 HydrophobicContact CD2-CG1 4.35Å; L178-V180 HydrophobicContact CG-CG1 4.47Å
179R97.9Very high90.9Very high12 Ų1235 Ų355%0.04517%0.171CC..EExtended strand (participates in β ladder)trans-106.3142.5145.6-70.8178.3-69.6154.69.4107.7S62 R63 S66 G71 A72 T102 Q103 G104 P147S62-R179 CarbonylContact O-C 3.24Å; S62-R179 VanDerWaalsContact O-CA 3.24Å; S62-R179 WeakPolarHBondContact O-CA 3.44Å; R63-R179 VanDerWaalsContact O-CD 3.27Å; R63-R179 WeakPolarHBondContact O-CD 3.18Å; R63-R179 WeakPolarHBondContact O-CG 3.45Å; S66-R179 VanDerWaalsContact O-CD 3.32Å; S66-R179 WeakPolarHBondContact O-CD 3.32Å; S66-R179 PolarHBondContact O-NH1 2.78Å; G71-R179 VanDerWaalsContact O-CD 3.28Å; G71-R179 WeakPolarHBondContact O-CD 3.49Å; G71-R179 PolarHBondContact O-NE 2.81Å; A72-R179 HydrophobicContact CB-CG 3.99Å; T102-R179 CarbonylContact C-O 3.47Å; T102-R179 WeakPolarHBondContact CA-O 3.38Å; Q103-R179 HydrophobicContact CB-CB 4.15Å; Q103-R179 VanDerWaalsContact CD-CZ 3.41Å; Q103-R179 PolarHBondContact N-O 3.07Å; Q103-R179 PolarHBondContact O-N 2.9Å; G104-R179 VanDerWaalsContact O-CZ 3.27Å; G104-R179 PolarHBondContact O-NE 3.2Å; G104-R179 PolarHBondContact O-NH2 3.35Å; P147-R179 PolarHBondContact O-NH2 3.08Å
180V98.2Very high90.9Very high0 Ų031.7 Ų31.70%016%0.158CC..EExtended strand (participates in β ladder)trans-139.2156.3-174.6-49.60000112.1M37 S62 L64 L87 G101 T102 F166 L178M37-V180 WeakPolarHBondContact CB-O 3.4Å; M37-V180 HydrophobicContact CE-CG2 3.81Å; M37-V180 HydrophobicContact CG-CG2 4.37Å; M37-V180 WeakPolarHBondContact CG-O 3.31Å; S62-V180 PolarHBondContact O-N 2.86Å; L64-V180 PolarHBondContact N-O 3.05Å; L64-V180 VanDerWaalsContact N-O 3.11Å; L87-V180 HydrophobicContact CD2-CB 4.47Å; L87-V180 HydrophobicContact CD2-CG1 3.92Å; L87-V180 HydrophobicContact CD2-CG2 3.62Å; G101-V180 CarbonylContact O-C 3.44Å; G101-V180 VanDerWaalsContact O-CA 3.24Å; G101-V180 WeakPolarHBondContact O-CA 3.34Å; T102-V180 HydrophobicContact CG2-CG1 4.15Å; F166-V180 HydrophobicContact CD1-CB 4.5Å; F166-V180 HydrophobicContact CD1-CG1 3.9Å; F166-V180 HydrophobicContact CD2-CG1 4.26Å; F166-V180 HydrophobicContact CD2-CG2 4.26Å; F166-V180 HydrophobicContact CE1-CB 4.05Å; F166-V180 HydrophobicContact CE1-CG1 3.93Å; F166-V180 HydrophobicContact CE2-CB 4.13Å; F166-V180 HydrophobicContact CE2-CG1 4.32Å; F166-V180 HydrophobicContact CE2-CG2 3.85Å; F166-V180 HydrophobicContact CG-CG1 4.07Å; F166-V180 HydrophobicContact CZ-CB 3.85Å; F166-V180 HydrophobicContact CZ-CG1 4.14Å; F166-V180 HydrophobicContact CZ-CG2 4.06Å; L178-V180 HydrophobicContact CB-CG1 4.02Å; L178-V180 HydrophobicContact CD1-CG1 4.31Å; L178-V180 HydrophobicContact CD2-CG1 4.35Å; L178-V180 HydrophobicContact CG-CG1 4.47Å
181E98.1Very high91.4Very high0 Ų031.7 Ų31.70%016%0.158CC..EExtended strand (participates in β ladder)trans-135.7152.8162.4-175.757.5-86.500108.8A34 G36 M37 Q38 L64 V100 G101 Y183A34-E181 HydrophobicContact CB-CG 4.1Å; G36-E181 PolarHBondContact N-OE1 3.5Å; M37-E181 WeakPolarHBondContact CB-OE1 3.48Å; M37-E181 WeakPolarHBondContact CG-OE1 3.36Å; M37-E181 PolarHBondContact N-OE1 2.84Å; M37-E181 PolarHBondContact N-OE2 2.89Å; Q38-E181 WeakPolarHBondContact CB-OE2 3.5Å; Q38-E181 PolarHBondContact N-OE2 2.94Å; L64-E181 HydrophobicContact CB-CB 3.87Å; L64-E181 HydrophobicContact CD2-CB 3.83Å; L64-E181 HydrophobicContact CG-CB 4.3Å; V100-E181 WeakPolarHBondContact CA-O 3.43Å; G101-E181 PolarHBondContact N-O 3.12Å; G101-E181 PolarHBondContact O-N 2.86Å; E181-Y183 HydrophobicContact CB-CE2 3.89Å; E181-Y183 HydrophobicContact CG-CD1 4.46Å; E181-Y183 HydrophobicContact CG-CD2 4.36Å; E181-Y183 HydrophobicContact CG-CE1 3.9Å; E181-Y183 HydrophobicContact CG-CE2 3.8Å
182L97.7Very high92.1Very high0 Ų030.6 Ų30.60%015%0.152CC..EExtended strand (participates in β ladder)trans-113.5136.5173-6288.4000108.2L35 M37 V89 L91 V97 V100 V164 F166L35-L182 HydrophobicContact CB-CB 4.27Å; L35-L182 WeakPolarHBondContact CB-O 3.34Å; L35-L182 HydrophobicContact CD1-CB 4Å; L35-L182 HydrophobicContact CG-CB 4.36Å; L35-L182 WeakPolarHBondContact CG-O 3.41Å; L35-L182 PolarHBondContact N-O 2.91Å; M37-L182 HydrophobicContact CG-CD1 3.93Å; M37-L182 HydrophobicContact SD-CD1 4.44Å; V89-L182 HydrophobicContact CB-CD1 4.24Å; V89-L182 HydrophobicContact CG1-CD1 4.09Å; V89-L182 HydrophobicContact CG2-CD1 4.13Å; L91-L182 HydrophobicContact CD1-CD2 4.41Å; L91-L182 HydrophobicContact CD2-CD2 4.46Å; V97-L182 HydrophobicContact CG1-CB 4.29Å; V97-L182 HydrophobicContact CG1-CD2 4.27Å; V97-L182 HydrophobicContact CG2-CD2 4.35Å; V100-L182 HydrophobicContact CG1-CG 4.34Å; V164-L182 HydrophobicContact CB-CD2 3.77Å; V164-L182 HydrophobicContact CG1-CD2 3.98Å; V164-L182 HydrophobicContact CG2-CD2 3.69Å; F166-L182 HydrophobicContact CE2-CD1 4.13Å; F166-L182 HydrophobicContact CE2-CD2 4.47Å; F166-L182 HydrophobicContact CE2-CG 4.28Å; F166-L182 HydrophobicContact CZ-CD1 4.33Å; F166-L182 HydrophobicContact CZ-CG 4.18Å
183Y95.8Very high93Very high18 Ų1828.9 Ų28.97%0.07115%0.148CC..EExtended strand (participates in β ladder)trans-120.2135177.5-54.3-94.4000110.5Y33 A34 A98 L99 L152 E181 A409Y33-Y183 CarbonylContact O-C 3.54Å; Y33-Y183 VanDerWaalsContact O-CA 3.24Å; Y33-Y183 WeakPolarHBondContact O-CA 3.43Å; A34-Y183 HydrophobicContact CB-CD1 4.04Å; A34-Y183 HydrophobicContact CB-CE1 3.9Å; A98-Y183 PolarHBondContact N-O 2.86Å; L99-Y183 HydrophobicContact CB-CD2 4.12Å; L99-Y183 HydrophobicContact CB-CG 4.47Å; L99-Y183 HydrophobicContact CD2-CD2 4.39Å; L99-Y183 HydrophobicContact CD2-CG 4.43Å; L99-Y183 PolarHBondContact N-O 3.35Å; L99-Y183 PolarHBondContact O-N 3.43Å; L152-Y183 HydrophobicContact CD2-CD2 4.33Å; L152-Y183 HydrophobicContact CD2-CE2 3.56Å; E181-Y183 HydrophobicContact CB-CE2 3.89Å; E181-Y183 HydrophobicContact CG-CD1 4.46Å; E181-Y183 HydrophobicContact CG-CD2 4.36Å; E181-Y183 HydrophobicContact CG-CE1 3.9Å; E181-Y183 HydrophobicContact CG-CE2 3.8Å; Y183-A409 HydrophobicContact CD1-CB 3.93Å; Y183-A409 HydrophobicContact CE1-CB 3.94Å; Y183-A409 HydrophobicContact CG-CB 4.41Å
184G94.1Very high93.8Very high0 Ų024.3 Ų24.30%012%0.121CC..EExtended strand (participates in β ladder)trans178.1-153.6-167.800000113.3C31 Y33 L96C31-G184 CarbonylContact C-O 3.6Å; C31-G184 CarbonylContact O-C 3.57Å; C31-G184 WeakPolarHBondContact O-CA 3.27Å; C31-G184 VanDerWaalsContact SG-C 3.57Å; Y33-G184 PolarHBondContact N-O 3Å; Y33-G184 PolarHBondContact O-N 3.08Å; L96-G184 CarbonylContact O-C 3.55Å; L96-G184 WeakPolarHBondContact O-CA 3.32Å
185C92.1Very high94.7Very high32 Ų3224 Ų2422%0.21612%0.121CC..EExtended strand (participates in β ladder)trans-159.3167.3170.366.70000110.5C31 Y33 H95 L96C31-C185 HydrophobicContact CB-CB 4.02Å; C31-C185 WeakPolarHBondContact CB-SG 3.33Å; C31-C185 VanDerWaalsContact SG-CA 3.6Å; C31-C185 WeakPolarHBondContact SG-CB 3.13Å; C31-C185 PolarHBondContact SG-N 3.49Å; C31-C185 CovalentContact SG-SG 2.04Å; C31-C185 PolarHBondContact SG-SG 3.2Å; Y33-C185 HydrophobicContact CD2-CB 4.29Å; H95-C185 CarbonylContact C-O 3.43Å; H95-C185 WeakPolarHBondContact CA-O 3.47Å; H95-C185 WeakPolarHBondContact CB-O 3.3Å; L96-C185 PolarHBondContact N-O 2.96Å; L96-C185 PolarHBondContact O-N 3.45Å; L96-C185 VanDerWaalsContact O-N 3.08Å
186L91.7Very high95.2Very high46 Ų4620.6 Ų20.624%0.24110%0.098CC..EExtended strand (participates in β ladder)trans-73.8133.2-173.6-161.5147000111.9R188L186-R188 HydrophobicContact CD2-CG 4.16Å; L186-R188 PolarHBondContact O-N 3.24Å
187W93.7Very high95.4Very high12 Ų1221.4 Ų21.45%0.04510%0.103CC..  trans-74.687.6179.9-169.7-117.7000110.7F26 L94 L96 V160 D189 L191 A232F26-W187 HydrophobicContact CD1-CH2 4.3Å; F26-W187 AromaticContact CD1-CZ3 3.82Å; F26-W187 HydrophobicContact CD1-CZ3 3.82Å; F26-W187 AromaticContact CE1-CH2 3.52Å; F26-W187 HydrophobicContact CE1-CH2 3.52Å; F26-W187 AromaticContact CE1-CZ3 3.35Å; F26-W187 HydrophobicContact CE1-CZ3 3.35Å; F26-W187 HydrophobicContact CE2-CZ3 4.18Å; F26-W187 HydrophobicContact CG-CZ3 4.44Å; F26-W187 AromaticContact CZ-CH2 3.84Å; F26-W187 HydrophobicContact CZ-CH2 3.84Å; F26-W187 AromaticContact CZ-CZ3 3.54Å; F26-W187 HydrophobicContact CZ-CZ3 3.54Å; L94-W187 HydrophobicContact CB-CB 3.67Å; L94-W187 HydrophobicContact CB-CG 4.16Å; L94-W187 VanDerWaalsContact O-CB 3.29Å; L94-W187 WeakPolarHBondContact O-CB 3.29Å; L94-W187 PolarHBondContact O-N 2.83Å; L96-W187 HydrophobicContact CB-CE3 4.23Å; L96-W187 HydrophobicContact CD1-CE3 4.48Å; L96-W187 HydrophobicContact CD1-CZ3 4.12Å; V160-W187 HydrophobicContact CG1-CB 4.44Å; V160-W187 HydrophobicContact CG1-CD2 3.77Å; V160-W187 HydrophobicContact CG1-CE3 4.36Å; V160-W187 HydrophobicContact CG1-CG 3.78Å; V160-W187 HydrophobicContact CG1-CZ2 4.48Å; V160-W187 HydrophobicContact CG2-CD2 4Å; V160-W187 HydrophobicContact CG2-CE3 3.83Å; V160-W187 HydrophobicContact CG2-CH2 3.8Å; V160-W187 HydrophobicContact CG2-CZ2 3.96Å; V160-W187 HydrophobicContact CG2-CZ3 3.73Å; W187-D189 HydrophobicContact CZ2-CB 4.3Å; W187-L191 HydrophobicContact CZ2-CB 4.44Å; W187-L191 PolarHBondContact NE1-O 2.82Å; W187-A232 HydrophobicContact CH2-CB 4.31Å; W187-A232 HydrophobicContact CZ2-CB 4.49Å
188R89.6Confident95.4Very high196 Ų19623.6 Ų23.674%0.7412%0.116SC*.  trans-73.8-38.4-173.8-70.9179.8-178.3-93.81.5112.9L186 G190 R278L186-R188 HydrophobicContact CD2-CG 4.16Å; L186-R188 PolarHBondContact O-N 3.24Å; R188-G190 VanDerWaalsContact C-N 3.33Å; R188-G190 PolarHBondContact O-N 2.72Å; R188-R278 PolarHBondContact O-NH1 2.86Å; R188-R278 PolarHBondContact O-NH2 3.22Å
189D90Very high95.4Very high15 Ų1524 Ų248%0.0812%0.12CC..SBendtrans-49.5-51.7175.8-177.2-62.7000111.7W187 L191 R278 S363 F364W187-D189 HydrophobicContact CZ2-CB 4.3Å; D189-L191 WeakPolarHBondContact OD1-CB 3.33Å; D189-L191 PolarHBondContact OD1-N 3.06Å; D189-R278 PolarHBondContact O-NH1 2.95Å; D189-S363 WeakPolarHBondContact OD2-CA 3.48Å; D189-F364 PolarHBondContact OD2-N 3.23Å
190G91.8Very high95.4Very high1 Ų125.8 Ų25.81%0.0113%0.129CC..  trans870175.600000115.4R188 L192 F274 D275 R278R188-G190 VanDerWaalsContact C-N 3.33Å; R188-G190 PolarHBondContact O-N 2.72Å; G190-L192 PolarHBondContact O-N 3.1Å; G190-F274 CarbonylContact O-C 3.51Å; G190-F274 WeakPolarHBondContact O-CA 3.34Å; G190-D275 PolarHBondContact O-N 2.87Å; G190-R278 VanDerWaalsContact CA-NH2 3.33Å
191L95.6Very high95.3Very high1 Ų127.7 Ų27.71%0.00514%0.14CC..EExtended strand (participates in β ladder)trans-54.1125.9170.7-170.269.9000110.9W187 D189 Y194 L228 A232 F272 F274 F364W187-L191 HydrophobicContact CZ2-CB 4.44Å; W187-L191 PolarHBondContact NE1-O 2.82Å; D189-L191 WeakPolarHBondContact OD1-CB 3.33Å; D189-L191 PolarHBondContact OD1-N 3.06Å; L191-Y194 HydrophobicContact CD2-CD1 4.06Å; L191-L228 HydrophobicContact CD2-CD2 3.67Å; L191-L228 HydrophobicContact CG-CD2 3.84Å; L191-A232 HydrophobicContact CD2-CB 4.25Å; L191-F272 HydrophobicContact CD1-CB 3.65Å; L191-F272 HydrophobicContact CD1-CD1 3.82Å; L191-F272 HydrophobicContact CD1-CG 4.24Å; L191-F272 HydrophobicContact CD2-CD1 4.28Å; L191-F274 HydrophobicContact CB-CD1 4.22Å; L191-F274 HydrophobicContact CB-CE1 3.99Å; L191-F274 HydrophobicContact CD1-CD1 4.35Å; L191-F274 HydrophobicContact CD1-CE1 3.87Å; L191-F274 HydrophobicContact CD1-CE2 4.15Å; L191-F274 HydrophobicContact CD1-CZ 3.76Å; L191-F364 HydrophobicContact CD1-CE2 4.4Å; L191-F364 HydrophobicContact CD2-CE2 4.38Å
192L94.5Very high95.1Very high36 Ų3627.9 Ų27.919%0.18814%0.141CC..EExtended strand (participates in β ladder)trans-91.8-37.1175.5-77.7174.5000111.9L94 R124 G190 E273 D275L94-L192 HydrophobicContact CD1-CD2 3.73Å; L94-L192 HydrophobicContact CD2-CD2 4.43Å; R124-L192 HydrophobicContact CB-CD2 4.29Å; R124-L192 PolarHBondContact NE-O 3.33Å; G190-L192 PolarHBondContact O-N 3.1Å; L192-E273 HydrophobicContact CD1-CG 4.3Å; L192-E273 PolarHBondContact N-O 2.88Å; L192-D275 HydrophobicContact CD2-CB 4.48Å; L192-D275 HydrophobicContact CG-CB 4.3Å
193S96.9Very high94.8Very high15 Ų1536.5 Ų36.511%0.10518%0.175CC..EExtended strand (participates in β ladder)trans-166.3150.4177.353.90000110.8G227 E273S193-G227 CarbonylContact C-O 3.44Å; S193-G227 WeakPolarHBondContact CA-O 3.16Å; S193-G227 VanDerWaalsContact CB-O 3.23Å; S193-G227 WeakPolarHBondContact CB-O 3.36Å; S193-E273 PolarHBondContact O-N 2.94Å
194Y98.1Very high94.5Very high2 Ų238.8 Ų38.81%0.00819%0.188CC..EExtended strand (participates in β ladder)trans-111.4157.6161.761.3-101.5000110.8L191 A196 D212 Y215 G227 L228 G229 L231 A232 E271 F272L191-Y194 HydrophobicContact CD2-CD1 4.06Å; Y194-A196 HydrophobicContact CD2-CB 4.35Å; Y194-D212 PolarHBondContact OH-OD2 3.16Å; Y194-Y215 AromaticContact CD2-CE2 4Å; Y194-Y215 HydrophobicContact CD2-CE2 4Å; Y194-Y215 AromaticContact CE2-CD2 3.84Å; Y194-Y215 HydrophobicContact CE2-CD2 3.84Å; Y194-Y215 AromaticContact CE2-CE2 3.44Å; Y194-Y215 HydrophobicContact CE2-CE2 3.44Å; Y194-Y215 VanDerWaalsContact CE2-CE2 3.44Å; Y194-Y215 AromaticContact CZ-CD2 3.87Å; Y194-Y215 AromaticContact CZ-CE2 3.75Å; Y194-Y215 PolarHBondContact O-OH 2.88Å; Y194-G227 PolarHBondContact N-O 3.06Å; Y194-L228 HydrophobicContact CD1-CD2 3.86Å; Y194-L228 HydrophobicContact CE1-CD2 4.18Å; Y194-G229 VanDerWaalsContact OH-CA 3.25Å; Y194-G229 WeakPolarHBondContact OH-CA 3.48Å; Y194-G229 PolarHBondContact OH-N 2.91Å; Y194-L231 HydrophobicContact CE1-CB 3.84Å; Y194-L231 HydrophobicContact CE2-CB 4.41Å; Y194-L231 HydrophobicContact CE2-CD1 4.07Å; Y194-A232 HydrophobicContact CE1-CB 4.3Å; Y194-E271 CarbonylContact C-O 3.6Å; Y194-E271 VanDerWaalsContact CA-O 3.25Å; Y194-E271 WeakPolarHBondContact CA-O 3.18Å; Y194-F272 HydrophobicContact CG-CE1 4.49Å
195T98.2Very high94Very high38 Ų3844.3 Ų44.323%0.23323%0.227CC..EExtended strand (participates in β ladder)trans-121.6126.7176.4-64.50000107.9L223 Q224 M270 E271T195-L223 HydrophobicContact CG2-CD1 4.13Å; T195-L223 HydrophobicContact CG2-CD2 4.07Å; T195-L223 HydrophobicContact CG2-CG 4.16Å; T195-Q224 CarbonylContact C-O 3.56Å; T195-Q224 WeakPolarHBondContact CA-O 3.38Å; T195-Q224 WeakPolarHBondContact CG2-O 3.44Å; T195-M270 CarbonylContact O-C 3.49Å; T195-M270 WeakPolarHBondContact O-CA 3.24Å; T195-M270 WeakPolarHBondContact O-CB 3.44Å; T195-E271 PolarHBondContact N-O 2.54Å; T195-E271 PolarHBondContact O-N 2.88Å
196A97.8Very high93.9Very high2 Ų246.9 Ų46.92%0.01724%0.236CC..EExtended strand (participates in β ladder)trans-150.5156-174.500000111.4Y194 L223 Q224 M270Y194-A196 HydrophobicContact CD2-CB 4.35Å; A196-L223 WeakPolarHBondContact O-CD1 3.21Å; A196-Q224 PolarHBondContact N-O 2.96Å; A196-Q224 PolarHBondContact O-N 2.84Å; A196-M270 HydrophobicContact CB-CE 4.12Å; A196-M270 HydrophobicContact CB-CG 3.97Å; A196-M270 HydrophobicContact CB-SD 4.44Å
197P97.8Very high93.9Very high21 Ų2146 Ų4614%0.13624%0.235CC..EExtended strand (participates in β ladder)trans-62.8146168.2-17.531.5000110.6G199 W258 F263 V268 E269P197-G199 PolarHBondContact O-N 3.15Å; P197-W258 PolarHBondContact O-NE1 2.75Å; P197-F263 HydrophobicContact CB-CE1 4.09Å; P197-F263 HydrophobicContact CB-CZ 3.74Å; P197-F263 HydrophobicContact CG-CE1 3.77Å; P197-F263 HydrophobicContact CG-CZ 3.86Å; P197-V268 HydrophobicContact CG-CG1 4.2Å; P197-E269 WeakPolarHBondContact CD-O 3.5Å
198V97.4Very high94.1Very high49 Ų4945.4 Ų45.430%0.29723%0.233SC..PPolyproline II helixtrans-57.7126.3175.1172.40000110.1T219 G222 Q224V198-T219 HydrophobicContact CG2-CG2 3.46Å; V198-T219 VanDerWaalsContact CG2-CG2 3.46Å; V198-G222 WeakPolarHBondContact CG2-O 3.38Å; V198-G222 PolarHBondContact N-O 3.06Å; V198-Q224 HydrophobicContact CB-CG 4.5Å; V198-Q224 HydrophobicContact CG2-CG 3.6Å
199G96.4Very high94.4Very high7 Ų740.9 Ų40.97%0.07222%0.216CC..PPolyproline II helixtrans-63.6151.2175.900000113P197 L210 G257P197-G199 PolarHBondContact O-N 3.15Å; G199-L210 CarbonylContact C-O 3.56Å; G199-L210 WeakPolarHBondContact CA-O 3.39Å; G199-G257 CarbonylContact C-O 3.37Å; G199-G257 WeakPolarHBondContact CA-O 3.25Å
200Q97.3Very high94.8Very high50 Ų5040.2 Ų40.223%0.23421%0.213CC..  trans-114.8163.4-159.9-55.5-172.6-43.900113.2L210 G257 S259 S262 W356Q200-L210 PolarHBondContact N-O 2.04Å; Q200-L210 WeakPolarHBondContact O-CA 3.42Å; Q200-L210 VanDerWaalsContact O-CB 3.25Å; Q200-L210 WeakPolarHBondContact O-CB 3.29Å; Q200-L210 PolarHBondContact O-N 2.92Å; Q200-G257 PolarHBondContact N-O 3.36Å; Q200-S259 PolarHBondContact OE1-OG 2.86Å; Q200-S262 VanDerWaalsContact NE2-CB 3.32Å; Q200-S262 PolarHBondContact NE2-OG 3.02Å; Q200-S262 PolarHBondContact OE1-OG 2.86Å; Q200-W356 HydrophobicContact CB-CH2 4.09Å; Q200-W356 HydrophobicContact CB-CZ3 3.95Å
201T96.4Very high95Very high40 Ų4042.3 Ų42.325%0.24522%0.224CC..EExtended strand (participates in β ladder)trans-91.3125.3174.7-49.90000111.1Y203 A207 V208 Y209 W356T201-Y203 HydrophobicContact CG2-CD1 4.41Å; T201-Y203 HydrophobicContact CG2-CE1 3.96Å; T201-Y203 HydrophobicContact CG2-CE2 4.2Å; T201-A207 HydrophobicContact CG2-CB 4.17Å; T201-V208 CarbonylContact C-O 3.55Å; T201-V208 WeakPolarHBondContact CA-O 3.18Å; T201-V208 WeakPolarHBondContact CG2-O 3.3Å; T201-Y209 HydrophobicContact CG2-CD1 3.87Å; T201-Y209 HydrophobicContact CG2-CE1 4.05Å; T201-Y209 HydrophobicContact CG2-CG 4.31Å; T201-W356 WeakPolarHBondContact O-CH2 3.39Å
202M95.3Very high95.1Very high5 Ų542.8 Ų42.83%0.02523%0.226CC..EExtended strand (participates in β ladder)trans-91.8120.9169-171.1-167.7-4700109.5L204 V208 L210 F241 W356 L358M202-L204 HydrophobicContact CG-CD2 4.17Å; M202-L204 HydrophobicContact CG-CG 4.04Å; M202-L204 HydrophobicContact SD-CD1 3.75Å; M202-L204 HydrophobicContact SD-CD2 3.73Å; M202-L204 HydrophobicContact SD-CG 3.72Å; M202-V208 HydrophobicContact CB-CB 4.29Å; M202-V208 PolarHBondContact N-O 3.14Å; M202-V208 PolarHBondContact O-N 2.87Å; M202-L210 HydrophobicContact CB-CD1 3.88Å; M202-L210 HydrophobicContact CE-CD1 4Å; M202-F241 HydrophobicContact CE-CE2 3.73Å; M202-F241 HydrophobicContact CE-CZ 3.72Å; M202-F241 HydrophobicContact SD-CE2 4.21Å; M202-F241 HydrophobicContact SD-CZ 4.09Å; M202-W356 HydrophobicContact CB-CH2 3.79Å; M202-W356 HydrophobicContact CB-CZ2 3.61Å; M202-W356 HydrophobicContact CB-CZ3 4.29Å; M202-W356 HydrophobicContact CE-CB 4.23Å; M202-W356 HydrophobicContact CE-CD2 3.71Å; M202-W356 HydrophobicContact CE-CE3 4.21Å; M202-W356 HydrophobicContact CE-CG 3.67Å; M202-W356 HydrophobicContact CG-CD2 4.42Å; M202-W356 HydrophobicContact CG-CH2 4.36Å; M202-W356 HydrophobicContact CG-CZ2 3.67Å; M202-L358 HydrophobicContact CE-CD2 4.45Å
203Y91.6Very high95.1Very high181 Ų18142.9 Ų42.971%0.7123%0.23SC*.EExtended strand (participates in β ladder)trans-91.9104.8176.6-61.5-81.6000109.9T201 A207T201-Y203 HydrophobicContact CG2-CD1 4.41Å; T201-Y203 HydrophobicContact CG2-CE1 3.96Å; T201-Y203 HydrophobicContact CG2-CE2 4.2Å; Y203-A207 HydrophobicContact CD1-CB 4.34Å; Y203-A207 HydrophobicContact CE1-CB 4.38Å
204L88.2Confident95.1Very high65 Ų6543.4 Ų43.434%0.3423%0.233SC..SBendtrans-107.7-141.7173.2-63.6179.7000109M202 E206 V208 L293M202-L204 HydrophobicContact CG-CD2 4.17Å; M202-L204 HydrophobicContact CG-CG 4.04Å; M202-L204 HydrophobicContact SD-CD1 3.75Å; M202-L204 HydrophobicContact SD-CD2 3.73Å; M202-L204 HydrophobicContact SD-CG 3.72Å; L204-E206 PolarHBondContact N-O 2.9Å; L204-E206 PolarHBondContact O-N 2.91Å; L204-V208 HydrophobicContact CD1-CG2 4.12Å; L204-L293 HydrophobicContact CD1-CB 4.44Å; L204-L293 HydrophobicContact CD1-CD1 4.1Å; L204-L293 HydrophobicContact CD1-CD2 4.28Å
205S84.6Confident95Very high117 Ų11744.7 Ų44.782%0.81824%0.238SC*.SBendtrans-62.7-20.2164.651.30000113.2
206E89.2Confident94.9Very high86 Ų8643.9 Ų43.940%0.40223%0.232SC..SBendtrans-137.3162.9173.367.4-160.914500108.8L204 V208 P251L204-E206 PolarHBondContact N-O 2.9Å; L204-E206 PolarHBondContact O-N 2.91Å; E206-V208 HydrophobicContact CG-CG2 4.26Å; E206-V208 PolarHBondContact O-N 3.08Å; E206-P251 HydrophobicContact CG-CG 4.4Å
207A92.6Very high94.8Very high27 Ų2744.4 Ų44.422%0.22324%0.237CC..EExtended strand (participates in β ladder)trans-80.5118.2173.900000109.9T201 Y203 Y209T201-A207 HydrophobicContact CG2-CB 4.17Å; Y203-A207 HydrophobicContact CD1-CB 4.34Å; Y203-A207 HydrophobicContact CE1-CB 4.38Å; A207-Y209 HydrophobicContact CB-CE2 3.79Å; A207-Y209 WeakPolarHBondContact O-CE2 3.21Å
208V96.6Very high94.6Very high0 Ų047.4 Ų47.40%025%0.25CC..EExtended strand (participates in β ladder)trans-103.1111.8177.9-173.90000107.9T201 M202 L204 E206 L210 F241 R242 P251 G252T201-V208 CarbonylContact C-O 3.55Å; T201-V208 WeakPolarHBondContact CA-O 3.18Å; T201-V208 WeakPolarHBondContact CG2-O 3.3Å; M202-V208 HydrophobicContact CB-CB 4.29Å; M202-V208 PolarHBondContact N-O 3.14Å; M202-V208 PolarHBondContact O-N 2.87Å; L204-V208 HydrophobicContact CD1-CG2 4.12Å; E206-V208 HydrophobicContact CG-CG2 4.26Å; E206-V208 PolarHBondContact O-N 3.08Å; V208-L210 HydrophobicContact CG1-CD2 3.93Å; V208-L210 HydrophobicContact CG1-CG 4.12Å; V208-F241 HydrophobicContact CG1-CD2 4.02Å; V208-F241 HydrophobicContact CG1-CE2 4Å; V208-R242 HydrophobicContact CG1-CG 4.48Å; V208-R242 HydrophobicContact CG2-CG 4.01Å; V208-P251 CarbonylContact C-O 3.55Å; V208-P251 WeakPolarHBondContact CA-O 3.31Å; V208-P251 HydrophobicContact CG1-CB 4.43Å; V208-P251 WeakPolarHBondContact CG1-O 3.25Å; V208-P251 HydrophobicContact CG2-CB 4.28Å; V208-G252 VanDerWaalsContact CG1-CA 3.47Å
209Y96.8Very high94.4Very high101 Ų10149 Ų4940%0.39626%0.26SS..EExtended strand (participates in β ladder)trans-94.8113.7-175.5-55.4-96.7000109.3T201 A207 W250 P251 G252T201-Y209 HydrophobicContact CG2-CD1 3.87Å; T201-Y209 HydrophobicContact CG2-CE1 4.05Å; T201-Y209 HydrophobicContact CG2-CG 4.31Å; A207-Y209 HydrophobicContact CB-CE2 3.79Å; A207-Y209 WeakPolarHBondContact O-CE2 3.21Å; Y209-W250 HydrophobicContact CD2-CB 4.19Å; Y209-W250 HydrophobicContact CD2-CG 4.19Å; Y209-P251 PolarHBondContact N-O 2.97Å; Y209-G252 CarbonylContact O-C 3.54Å
210L97.4Very high94.2Very high0 Ų052.8 Ų52.80%028%0.281CS..  trans-112.539.9-174.7-50.8149.6000110G199 Q200 M202 V208 F241 Y255 V256 G257 W356 L358G199-L210 CarbonylContact C-O 3.56Å; G199-L210 WeakPolarHBondContact CA-O 3.39Å; Q200-L210 PolarHBondContact N-O 2.04Å; Q200-L210 WeakPolarHBondContact O-CA 3.42Å; Q200-L210 VanDerWaalsContact O-CB 3.25Å; Q200-L210 WeakPolarHBondContact O-CB 3.29Å; Q200-L210 PolarHBondContact O-N 2.92Å; M202-L210 HydrophobicContact CB-CD1 3.88Å; M202-L210 HydrophobicContact CE-CD1 4Å; V208-L210 HydrophobicContact CG1-CD2 3.93Å; V208-L210 HydrophobicContact CG1-CG 4.12Å; L210-F241 HydrophobicContact CD2-CD2 4.22Å; L210-Y255 CarbonylContact C-O 3.57Å; L210-Y255 WeakPolarHBondContact CA-O 3.32Å; L210-Y255 WeakPolarHBondContact CB-O 3.32Å; L210-V256 CarbonylContact O-C 3.55Å; L210-V256 WeakPolarHBondContact O-CA 3.09Å; L210-G257 PolarHBondContact O-N 2.74Å; L210-W356 HydrophobicContact CD1-CE3 4.02Å; L210-W356 HydrophobicContact CD1-CZ3 3.86Å; L210-L358 HydrophobicContact CD1-CD2 3.58Å; L210-L358 HydrophobicContact CD2-CD1 4.34Å; L210-L358 HydrophobicContact CD2-CD2 4.04Å; L210-L358 HydrophobicContact CG-CD2 4.29Å
211N96.5Very high93.7Very high46 Ų4654.8 Ų54.825%0.24632%0.315CS..SBendtrans-88.6149.8174.666.4-87.4000110.1S213 Q230N211-S213 PolarHBondContact O-N 2.94Å; N211-S213 VanDerWaalsContact O-N 3.12Å; N211-Q230 PolarHBondContact O-OE1 2.88Å
212D97.4Very high93.4Very high11 Ų1155.1 Ų55.16%0.05933%0.327CS..  trans-69114.5166.7-162-65.1000109.1Y194 T214 Y215 Q230 V256Y194-D212 PolarHBondContact OH-OD2 3.16Å; D212-T214 PolarHBondContact OD1-N 3.22Å; D212-T214 VanDerWaalsContact OD1-N 3.1Å; D212-Y215 WeakPolarHBondContact OD1-CB 3.36Å; D212-Y215 PolarHBondContact OD1-N 2.96Å; D212-Q230 PolarHBondContact OD1-N 2.91Å; D212-Q230 WeakPolarHBondContact OD2-CB 3.47Å; D212-Q230 PolarHBondContact OD2-N 3.4Å; D212-V256 HydrophobicContact CB-CG1 4.26Å; D212-V256 HydrophobicContact CB-CG2 3.72Å; D212-V256 WeakPolarHBondContact OD2-CG2 3.21Å
213S95Very high93.4Very high38 Ų3858.6 Ų58.627%0.26635%0.345SS..SBendtrans-87.7-17.4-174.7-172.70000113.7N211 W250 Y253N211-S213 PolarHBondContact O-N 2.94Å; N211-S213 VanDerWaalsContact O-N 3.12Å; S213-W250 WeakPolarHBondContact OG-CH2 3.26Å; S213-W250 WeakPolarHBondContact OG-CZ2 3.49Å; S213-Y253 WeakPolarHBondContact OG-CE2 3.36Å
214T95.9Very high93.6Very high26 Ų2650.3 Ų50.316%0.1631%0.312CS..SBendtrans-115.91-171.261.60000113.2P157 D212 D216 Q230P157-T214 HydrophobicContact CB-CG2 3.96Å; P157-T214 HydrophobicContact CG-CG2 3.74Å; D212-T214 PolarHBondContact OD1-N 3.22Å; D212-T214 VanDerWaalsContact OD1-N 3.1Å; T214-D216 PolarHBondContact O-N 3.18Å; T214-D216 VanDerWaalsContact O-N 3.15Å; T214-Q230 HydrophobicContact CG2-CG 4.12Å; T214-Q230 WeakPolarHBondContact OG1-CG 3.46Å; T214-Q230 PolarHBondContact OG1-N 3.34Å; T214-Q230 VanDerWaalsContact OG1-N 3.15Å
215Y97.4Very high94Very high28 Ų2851.7 Ų51.711%0.1131%0.314CS..  trans-51.4112.2-176.7-161.7-102.6000114.7Y194 D212 G217 Q224 Y225 G226 G227 L228Y194-Y215 AromaticContact CD2-CE2 4Å; Y194-Y215 HydrophobicContact CD2-CE2 4Å; Y194-Y215 AromaticContact CE2-CD2 3.84Å; Y194-Y215 HydrophobicContact CE2-CD2 3.84Å; Y194-Y215 AromaticContact CE2-CE2 3.44Å; Y194-Y215 HydrophobicContact CE2-CE2 3.44Å; Y194-Y215 VanDerWaalsContact CE2-CE2 3.44Å; Y194-Y215 AromaticContact CZ-CD2 3.87Å; Y194-Y215 AromaticContact CZ-CE2 3.75Å; Y194-Y215 PolarHBondContact O-OH 2.88Å; D212-Y215 WeakPolarHBondContact OD1-CB 3.36Å; D212-Y215 PolarHBondContact OD1-N 2.96Å; Y215-G217 VanDerWaalsContact C-N 3.34Å; Y215-G217 PolarHBondContact O-N 2.8Å; Y215-Q224 HydrophobicContact CD1-CB 4.02Å; Y215-Q224 HydrophobicContact CD1-CG 4.49Å; Y215-Q224 HydrophobicContact CE1-CB 3.71Å; Y215-Q224 HydrophobicContact CE2-CB 4.34Å; Y215-Q224 HydrophobicContact CG-CB 4.44Å; Y215-Y225 WeakPolarHBondContact OH-CA 3.24Å; Y215-Y225 PolarHBondContact OH-N 2.75Å; Y215-Y225 VanDerWaalsContact OH-N 3.17Å; Y215-Y225 PolarHBondContact OH-O 3.13Å; Y215-G226 PolarHBondContact OH-N 3.34Å; Y215-G227 WeakPolarHBondContact CE2-O 3.45Å; Y215-G227 PolarHBondContact OH-N 2.67Å; Y215-G227 PolarHBondContact OH-O 3Å; Y215-L228 CarbonylContact C-O 3.52Å; Y215-L228 VanDerWaalsContact CA-O 3.29Å; Y215-L228 WeakPolarHBondContact CA-O 3.41Å
216D96.3Very high94.4Very high21 Ų2147.6 Ų47.611%0.11229%0.29CS..  trans-85.40.7-173.776.76.9000115Y122 R124 R128 M130 T214 G227 L228Y122-D216 VanDerWaalsContact OH-CB 3.3Å; Y122-D216 WeakPolarHBondContact OH-CB 3.45Å; Y122-D216 PolarHBondContact OH-OD2 3.01Å; R124-D216 IonicContact CZ-OD1 2.7Å; R124-D216 IonicContact CZ-OD2 3.31Å; R124-D216 VanDerWaalsContact CZ-OD2 3.25Å; R124-D216 IonicContact NH1-OD2 3.76Å; R124-D216 PolarHBondContact NH1-OD2 3.08Å; R124-D216 VanDerWaalsContact NH2-CG 3.28Å; R124-D216 IonicContact NH2-OD1 2.87Å; R124-D216 PolarHBondContact NH2-OD1 3.49Å; R124-D216 IonicContact NH2-OD2 3.3Å; R124-D216 PolarHBondContact NH2-OD2 3.07Å; R128-D216 PolarHBondContact NH2-O 3.25Å; M130-D216 HydrophobicContact CG-CB 4.4Å; M130-D216 HydrophobicContact SD-CB 3.95Å; M130-D216 VanDerWaalsContact SD-OD2 3.41Å; T214-D216 PolarHBondContact O-N 3.18Å; T214-D216 VanDerWaalsContact O-N 3.15Å; D216-G227 WeakPolarHBondContact OD1-CA 3.22Å; D216-L228 PolarHBondContact N-O 3.22Å; D216-L228 PolarHBondContact OD1-N 3.08Å
217G94.6Very high94.7Very high13 Ų1343.5 Ų43.513%0.13427%0.271CS..SBendtrans-90-129.8-172.500000114.9R128 Y215R128-G217 VanDerWaalsContact NH2-C 3.29Å; R128-G217 PolarHBondContact NH2-O 2.77Å; Y215-G217 VanDerWaalsContact C-N 3.34Å; Y215-G217 PolarHBondContact O-N 2.8Å
218H93.6Very high95Very high85 Ų8542.6 Ų42.639%0.39426%0.263SS..EExtended strand (participates in β ladder)trans-126.2142172.5-71.1-72.9000110.6R128 Q224 Y225R128-H218 PolarHBondContact NH1-CD2 3.33Å; R128-H218 PolarHBondContact NH1-NE2 3.09Å; H218-Q224 CarbonylContact O-C 3.51Å; H218-Q224 VanDerWaalsContact O-CA 3.32Å; H218-Q224 WeakPolarHBondContact O-CA 3.09Å; H218-Y225 HydrophobicContact CB-CD1 4.25Å; H218-Y225 HydrophobicContact CB-CD2 4.39Å; H218-Y225 HydrophobicContact CB-CE1 3.76Å; H218-Y225 HydrophobicContact CB-CE2 3.92Å; H218-Y225 PolarHBondContact N-O 3.39Å; H218-Y225 PolarHBondContact O-N 2.7Å
219T94.1Very high94.9Very high83 Ų8342.9 Ų42.951%0.50927%0.266SS..EExtended strand (participates in β ladder)trans-120.4113.8172.9-55.90000108.7V198 L223 Q224V198-T219 HydrophobicContact CG2-CG2 3.46Å; V198-T219 VanDerWaalsContact CG2-CG2 3.46Å; T219-L223 CarbonylContact C-O 3.46Å; T219-L223 WeakPolarHBondContact CA-O 3.44Å; T219-Q224 HydrophobicContact CG2-CG 4.15Å
220V91.9Very high94.9Very high86 Ų8638.4 Ų38.452%0.52125%0.248SC..EExtended strand (participates in β ladder)trans-141.1131.7-177.2-174.70000109.5G222 L223 Y225V220-G222 PolarHBondContact O-N 2.96Å; V220-G222 VanDerWaalsContact O-N 3.12Å; V220-L223 PolarHBondContact N-O 3.42Å; V220-L223 PolarHBondContact O-N 2.73Å; V220-Y225 HydrophobicContact CB-CE1 4.07Å; V220-Y225 HydrophobicContact CG2-CE1 3.88Å
221G86.3Confident94.9Very high91 Ų9138.5 Ų38.594%0.93825%0.249SC*.THydrogen-bonded Turntrans61.821.5172.100000115.8
222G90.6Very high94.8Very high48 Ų4836.5 Ų36.550%0.49524%0.238SC..THydrogen-bonded Turntrans87.37.1-174.500000114.9V198 V220V198-G222 WeakPolarHBondContact CG2-O 3.38Å; V198-G222 PolarHBondContact N-O 3.06Å; V220-G222 PolarHBondContact O-N 2.96Å; V220-G222 VanDerWaalsContact O-N 3.12Å
223L94.1Very high94.5Very high77 Ų7736.3 Ų36.340%0.40324%0.237SC..EExtended strand (participates in β ladder)trans-115.3137.1174.3-169.374.3000111T195 A196 T219 V220T195-L223 HydrophobicContact CG2-CD1 4.13Å; T195-L223 HydrophobicContact CG2-CD2 4.07Å; T195-L223 HydrophobicContact CG2-CG 4.16Å; A196-L223 WeakPolarHBondContact O-CD1 3.21Å; T219-L223 CarbonylContact C-O 3.46Å; T219-L223 WeakPolarHBondContact CA-O 3.44Å; V220-L223 PolarHBondContact N-O 3.42Å; V220-L223 PolarHBondContact O-N 2.73Å
224Q96.4Very high94.1Very high7 Ų734.7 Ų34.73%0.03323%0.227CC..EExtended strand (participates in β ladder)trans-101.3129.4171.2-57-174.1-98.300108.7T195 A196 V198 Y215 H218 T219T195-Q224 CarbonylContact C-O 3.56Å; T195-Q224 WeakPolarHBondContact CA-O 3.38Å; T195-Q224 WeakPolarHBondContact CG2-O 3.44Å; A196-Q224 PolarHBondContact N-O 2.96Å; A196-Q224 PolarHBondContact O-N 2.84Å; V198-Q224 HydrophobicContact CB-CG 4.5Å; V198-Q224 HydrophobicContact CG2-CG 3.6Å; Y215-Q224 HydrophobicContact CD1-CB 4.02Å; Y215-Q224 HydrophobicContact CD1-CG 4.49Å; Y215-Q224 HydrophobicContact CE1-CB 3.71Å; Y215-Q224 HydrophobicContact CE2-CB 4.34Å; Y215-Q224 HydrophobicContact CG-CB 4.44Å; H218-Q224 CarbonylContact O-C 3.51Å; H218-Q224 VanDerWaalsContact O-CA 3.32Å; H218-Q224 WeakPolarHBondContact O-CA 3.09Å; T219-Q224 HydrophobicContact CG2-CG 4.15Å
225Y96.4Very high93.8Very high94 Ų9434.6 Ų34.637%0.36923%0.227SC..EExtended strand (participates in β ladder)trans-150.1157-179.267.8-84.5000113.5Y215 H218 V220 G227Y215-Y225 WeakPolarHBondContact OH-CA 3.24Å; Y215-Y225 PolarHBondContact OH-N 2.75Å; Y215-Y225 VanDerWaalsContact OH-N 3.17Å; Y215-Y225 PolarHBondContact OH-O 3.13Å; H218-Y225 HydrophobicContact CB-CD1 4.25Å; H218-Y225 HydrophobicContact CB-CD2 4.39Å; H218-Y225 HydrophobicContact CB-CE1 3.76Å; H218-Y225 HydrophobicContact CB-CE2 3.92Å; H218-Y225 PolarHBondContact N-O 3.39Å; H218-Y225 PolarHBondContact O-N 2.7Å; V220-Y225 HydrophobicContact CB-CE1 4.07Å; V220-Y225 HydrophobicContact CG2-CE1 3.88Å; Y225-G227 VanDerWaalsContact C-N 3.32Å; Y225-G227 PolarHBondContact O-N 3.49Å
226G93.4Very high93.5Very high32 Ų3235.2 Ų35.233%0.3323%0.233SC..EExtended strand (participates in β ladder)trans71.419.6172.900000115.6Y215Y215-G226 PolarHBondContact OH-N 3.34Å
227G96.1Very high93.4Very high0 Ų034.4 Ų34.40%023%0.23CC..EExtended strand (participates in β ladder)trans-145.4-178.5177.800000115.1S193 Y194 Y215 D216 Y225S193-G227 CarbonylContact C-O 3.44Å; S193-G227 WeakPolarHBondContact CA-O 3.16Å; S193-G227 VanDerWaalsContact CB-O 3.23Å; S193-G227 WeakPolarHBondContact CB-O 3.36Å; Y194-G227 PolarHBondContact N-O 3.06Å; Y215-G227 WeakPolarHBondContact CE2-O 3.45Å; Y215-G227 PolarHBondContact OH-N 2.67Å; Y215-G227 PolarHBondContact OH-O 3Å; D216-G227 WeakPolarHBondContact OD1-CA 3.22Å; Y225-G227 VanDerWaalsContact C-N 3.32Å; Y225-G227 PolarHBondContact O-N 3.49Å
228L97.4Very high93.3Very high8 Ų837 Ų374%0.04224%0.24CC..  trans-122.3161.2171.8-64.5172.7000108.8V160 L191 Y194 Y215 D216 A232V160-L228 HydrophobicContact CB-CD1 3.76Å; V160-L228 HydrophobicContact CG1-CD1 3.97Å; V160-L228 HydrophobicContact CG2-CD1 4Å; L191-L228 HydrophobicContact CD2-CD2 3.67Å; L191-L228 HydrophobicContact CG-CD2 3.84Å; Y194-L228 HydrophobicContact CD1-CD2 3.86Å; Y194-L228 HydrophobicContact CE1-CD2 4.18Å; Y215-L228 CarbonylContact C-O 3.52Å; Y215-L228 VanDerWaalsContact CA-O 3.29Å; Y215-L228 WeakPolarHBondContact CA-O 3.41Å; D216-L228 PolarHBondContact N-O 3.22Å; D216-L228 PolarHBondContact OD1-N 3.08Å; L228-A232 HydrophobicContact CD2-CB 4.29Å
229G96Very high93.4Very high6 Ų636.4 Ų36.46%0.06224%0.24CC..  trans-167-152.4-17500000109.4Y194 L231 A232 D233Y194-G229 VanDerWaalsContact OH-CA 3.25Å; Y194-G229 WeakPolarHBondContact OH-CA 3.48Å; Y194-G229 PolarHBondContact OH-N 2.91Å; G229-L231 VanDerWaalsContact C-N 3.3Å; G229-L231 PolarHBondContact O-N 3.47Å; G229-A232 CarbonylContact O-C 3.33Å; G229-A232 PolarHBondContact O-N 3.27Å; G229-D233 PolarHBondContact O-N 2.98Å
230Q95.9Very high93.4Very high7 Ų733.6 Ų33.63%0.03322%0.222CC..G310 helixtrans-56.1-39.3-172.2-59.6-169.4-108.600113.8N211 D212 T214 A232 D233 Y253 V256 S360N211-Q230 PolarHBondContact O-OE1 2.88Å; D212-Q230 PolarHBondContact OD1-N 2.91Å; D212-Q230 WeakPolarHBondContact OD2-CB 3.47Å; D212-Q230 PolarHBondContact OD2-N 3.4Å; T214-Q230 HydrophobicContact CG2-CG 4.12Å; T214-Q230 WeakPolarHBondContact OG1-CG 3.46Å; T214-Q230 PolarHBondContact OG1-N 3.34Å; T214-Q230 VanDerWaalsContact OG1-N 3.15Å; Q230-A232 PolarHBondContact O-N 3.5Å; Q230-D233 PolarHBondContact O-N 3.34Å; Q230-D233 VanDerWaalsContact O-N 3.07Å; Q230-Y253 PolarHBondContact NE2-O 2.9Å; Q230-Y253 PolarHBondContact OE1-O 3Å; Q230-V256 HydrophobicContact CB-CG2 4.36Å; Q230-S360 CarbonylContact C-O 3.49Å; Q230-S360 VanDerWaalsContact O-O 3.08Å
231L96.9Very high93.5Very high1 Ų129.5 Ų29.51%0.00520%0.197CC..G310 helixtrans-60.6-0.8175.6-60177.8000115.4Y194 G229 V256 W258 M270 F359 S360 I362Y194-L231 HydrophobicContact CE1-CB 3.84Å; Y194-L231 HydrophobicContact CE2-CB 4.41Å; Y194-L231 HydrophobicContact CE2-CD1 4.07Å; G229-L231 VanDerWaalsContact C-N 3.3Å; G229-L231 PolarHBondContact O-N 3.47Å; L231-V256 HydrophobicContact CD1-CB 4.32Å; L231-V256 HydrophobicContact CD1-CG2 4.32Å; L231-V256 HydrophobicContact CD2-CB 3.99Å; L231-V256 HydrophobicContact CD2-CG2 3.85Å; L231-V256 HydrophobicContact CG-CB 4.17Å; L231-V256 HydrophobicContact CG-CG2 3.76Å; L231-W258 HydrophobicContact CD1-CH2 4.2Å; L231-M270 HydrophobicContact CD1-CE 3.98Å; L231-F359 HydrophobicContact CD2-CB 3.71Å; L231-F359 WeakPolarHBondContact CD2-O 3.48Å; L231-S360 WeakPolarHBondContact CA-O 3.45Å; L231-I362 HydrophobicContact CB-CD1 4.47Å; L231-I362 HydrophobicContact CB-CG1 4.39Å; L231-I362 HydrophobicContact CD1-CD1 4.22Å; L231-I362 PolarHBondContact O-N 2.87Å
232A95Very high93.9Very high4 Ų428.7 Ų28.73%0.03317%0.165CC..G310 helixtrans-149.732.5171.700000111.9W187 L191 Y194 L228 G229 Q230 E361W187-A232 HydrophobicContact CH2-CB 4.31Å; W187-A232 HydrophobicContact CZ2-CB 4.49Å; L191-A232 HydrophobicContact CD2-CB 4.25Å; Y194-A232 HydrophobicContact CE1-CB 4.3Å; L228-A232 HydrophobicContact CD2-CB 4.29Å; G229-A232 CarbonylContact O-C 3.33Å; G229-A232 PolarHBondContact O-N 3.27Å; Q230-A232 PolarHBondContact O-N 3.5Å; A232-E361 WeakPolarHBondContact CA-OE2 3.37Å
233D90.2Very high94Very high7 Ų732.1 Ų32.14%0.03717%0.167CC..SBendtrans-97.5-7.6177.899.7-24.5000114.1F26 R135 P158 G229 Q230 V235 E361F26-D233 WeakPolarHBondContact CE2-O 3.32Å; F26-D233 VanDerWaalsContact CZ-C 3.48Å; R135-D233 IonicContact CZ-OD2 2.82Å; R135-D233 IonicContact NH1-OD2 3.02Å; R135-D233 PolarHBondContact NH1-OD2 3.17Å; R135-D233 IonicContact NH2-OD2 2.73Å; R135-D233 PolarHBondContact NH2-OD2 2.74Å; P158-D233 HydrophobicContact CG-CB 4.48Å; P158-D233 VanDerWaalsContact CG-O 3.29Å; P158-D233 WeakPolarHBondContact CG-O 3.45Å; G229-D233 PolarHBondContact O-N 2.98Å; Q230-D233 PolarHBondContact O-N 3.34Å; Q230-D233 VanDerWaalsContact O-N 3.07Å; D233-V235 WeakPolarHBondContact OD1-CB 3.47Å; D233-V235 WeakPolarHBondContact OD1-CG2 3.24Å; D233-V235 PolarHBondContact OD1-N 2.75Å; D233-E361 PolarHBondContact N-OE2 3.45Å
234G87.7Confident93.9Very high5 Ų529.8 Ų29.85%0.05216%0.157CC..SBendtrans8614.3177.100000114.3H25 F26 P28 E361H25-G234 PolarHBondContact CE1-O 2.7Å; H25-G234 VanDerWaalsContact CE1-O 3.22Å; F26-G234 VanDerWaalsContact CE2-CA 3.42Å; F26-G234 VanDerWaalsContact CZ-CA 3.42Å; P28-G234 WeakPolarHBondContact CD-O 3.42Å; G234-E361 PolarHBondContact N-OE2 3.01Å; G234-E361 VanDerWaalsContact N-OE2 3.1Å
235V89.1Confident93.4Very high24 Ų2435.3 Ų35.315%0.14518%0.183CC..  trans-100.6114.9171.9-179.20000111.6D233D233-V235 WeakPolarHBondContact OD1-CB 3.47Å; D233-V235 WeakPolarHBondContact OD1-CG2 3.24Å; D233-V235 PolarHBondContact OD1-N 2.75Å
236V91.9Very high92.9Very high41 Ų4133.7 Ų33.725%0.24818%0.178CC..PPolyproline II helixtrans-81.7117.6170.71700000109.5Q245V236-Q245 PolarHBondContact O-NE2 3.48Å
237G92.8Very high92.5Very high4 Ų438.5 Ų38.54%0.04120%0.196CC..PPolyproline II helixtrans-72.2151.6-179.600000113.7Y255 H286 S360G237-Y255 PolarHBondContact O-OH 3.01Å; G237-Y255 VanDerWaalsContact O-OH 3.13Å; G237-H286 PolarHBondContact O-CE1 3.18Å; G237-H286 VanDerWaalsContact O-CE1 3.27Å; G237-S360 WeakPolarHBondContact CA-OG 3.35Å; G237-S360 PolarHBondContact N-OG 2.88Å; G237-S360 VanDerWaalsContact N-OG 3.08Å
238L94.3Very high92Very high67 Ų6747.6 Ų47.635%0.35123%0.23SC..PPolyproline II helixtrans-68.4162.7-176.4-62.9177.1000113.8D240 K243 Q245 Y255 N288L238-D240 VanDerWaalsContact C-N 3.32Å; L238-D240 PolarHBondContact O-N 2.86Å; L238-K243 HydrophobicContact CD1-CB 4.12Å; L238-Q245 HydrophobicContact CD1-CG 4.3Å; L238-Q245 HydrophobicContact CD2-CG 3.86Å; L238-Q245 HydrophobicContact CG-CG 3.93Å; L238-Y255 VanDerWaalsContact O-CE2 3.3Å; L238-Y255 WeakPolarHBondContact O-CE2 3.25Å; L238-Y255 PolarHBondContact O-OH 2.93Å; L238-N288 PolarHBondContact O-ND2 3.01Å
239D94.1Very high91.7Very high73 Ų7348.8 Ų48.839%0.3924%0.238SC..SBendtrans-53.1-47.1172.7-77.6-31.7000112.3F241 N288 M290 R330 A331D239-F241 PolarHBondContact O-N 3.42Å; D239-N288 PolarHBondContact O-ND2 2.99Å; D239-M290 WeakPolarHBondContact O-CE 3.39Å; D239-R330 WeakPolarHBondContact OD1-CA 3.2Å; D239-R330 WeakPolarHBondContact OD1-CB 3.44Å; D239-A331 PolarHBondContact OD1-N 2.98Å
240D94.4Very high91.5Very high24 Ų2453.1 Ų53.113%0.12825%0.252CS..SBendtrans-89.188.3175-172.9-0.2000109.1L238 R242 K243 M290L238-D240 VanDerWaalsContact C-N 3.32Å; L238-D240 PolarHBondContact O-N 2.86Å; D240-R242 VanDerWaalsContact CG-NH2 3.28Å; D240-R242 PolarHBondContact O-N 3.38Å; D240-R242 IonicContact OD1-CZ 3.21Å; D240-R242 VanDerWaalsContact OD1-CZ 3.3Å; D240-R242 IonicContact OD1-NE 3.04Å; D240-R242 PolarHBondContact OD1-NE 3.09Å; D240-R242 IonicContact OD1-NH2 3.19Å; D240-R242 PolarHBondContact OD1-NH2 3.31Å; D240-R242 IonicContact OD2-CZ 3.87Å; D240-R242 IonicContact OD2-NH2 3.56Å; D240-R242 PolarHBondContact OD2-NH2 2.87Å; D240-K243 HydrophobicContact CB-CD 4.39Å; D240-K243 PolarHBondContact O-N 2.68Å; D240-K243 WeakPolarHBondContact OD2-CE 3.48Å; D240-K243 IonicContact OD2-NZ 2.67Å; D240-K243 PolarHBondContact OD2-NZ 3.15Å; D240-M290 HydrophobicContact CB-CE 3.93Å
241F95.1Very high91.5Very high0 Ų054.3 Ų54.30%026%0.261CS..THydrogen-bonded Turntrans-55.7-14.7-173.763-95.1000115.4M202 V208 L210 D239 K243 G252 Y255 N288 M290 L293 A295 L358M202-F241 HydrophobicContact CE-CE2 3.73Å; M202-F241 HydrophobicContact CE-CZ 3.72Å; M202-F241 HydrophobicContact SD-CE2 4.21Å; M202-F241 HydrophobicContact SD-CZ 4.09Å; V208-F241 HydrophobicContact CG1-CD2 4.02Å; V208-F241 HydrophobicContact CG1-CE2 4Å; L210-F241 HydrophobicContact CD2-CD2 4.22Å; D239-F241 PolarHBondContact O-N 3.42Å; F241-K243 PolarHBondContact O-N 3.3Å; F241-G252 WeakPolarHBondContact O-CA 3.41Å; F241-G252 PolarHBondContact O-N 3.33Å; F241-Y255 HydrophobicContact CB-CD2 3.52Å; F241-Y255 HydrophobicContact CB-CE2 3.57Å; F241-Y255 HydrophobicContact CB-CG 4.2Å; F241-N288 WeakPolarHBondContact CD1-OD1 3.32Å; F241-M290 HydrophobicContact CD1-CB 4.1Å; F241-M290 HydrophobicContact CD1-SD 4.43Å; F241-M290 HydrophobicContact CE1-CB 4.02Å; F241-M290 HydrophobicContact CE1-CG 4.31Å; F241-M290 HydrophobicContact CE1-SD 4.3Å; F241-L293 HydrophobicContact CE1-CB 3.87Å; F241-L293 HydrophobicContact CE1-CD1 4.01Å; F241-L293 HydrophobicContact CZ-CB 3.74Å; F241-L293 HydrophobicContact CZ-CD1 3.9Å; F241-L293 HydrophobicContact CZ-CG 4.49Å; F241-A295 HydrophobicContact CD1-CB 4.47Å; F241-A295 HydrophobicContact CE1-CB 4.12Å; F241-L358 HydrophobicContact CB-CD1 3.93Å; F241-L358 HydrophobicContact CD1-CD1 3.66Å; F241-L358 HydrophobicContact CD2-CD1 3.7Å; F241-L358 HydrophobicContact CE1-CD1 4Å; F241-L358 HydrophobicContact CE2-CD1 4.05Å; F241-L358 HydrophobicContact CG-CD1 3.48Å; F241-L358 VanDerWaalsContact CG-CD1 3.48Å; F241-L358 HydrophobicContact CZ-CD1 4.19Å
242R94.1Very high91.4Very high73 Ų7354.3 Ų54.328%0.27526%0.261SS..THydrogen-bonded Turntrans-75-12.8173.3-59.1171-63.4154.97.3112.7V208 D240 P251V208-R242 HydrophobicContact CG1-CG 4.48Å; V208-R242 HydrophobicContact CG2-CG 4.01Å; D240-R242 VanDerWaalsContact CG-NH2 3.28Å; D240-R242 PolarHBondContact O-N 3.38Å; D240-R242 IonicContact OD1-CZ 3.21Å; D240-R242 VanDerWaalsContact OD1-CZ 3.3Å; D240-R242 IonicContact OD1-NE 3.04Å; D240-R242 PolarHBondContact OD1-NE 3.09Å; D240-R242 IonicContact OD1-NH2 3.19Å; D240-R242 PolarHBondContact OD1-NH2 3.31Å; D240-R242 IonicContact OD2-CZ 3.87Å; D240-R242 IonicContact OD2-NH2 3.56Å; D240-R242 PolarHBondContact OD2-NH2 2.87Å; R242-P251 HydrophobicContact CB-CB 4.36Å; R242-P251 VanDerWaalsContact O-CA 3.28Å; R242-P251 WeakPolarHBondContact O-CA 3.3Å; R242-P251 WeakPolarHBondContact O-CB 3.4Å
243K92.6Very high91.5Very high121 Ų12154.1 Ų54.153%0.52626%0.259SS..SBendtrans-110.7144.9176.3-64.8170.4-176.2136.70109L238 D240 F241L238-K243 HydrophobicContact CD1-CB 4.12Å; D240-K243 HydrophobicContact CB-CD 4.39Å; D240-K243 PolarHBondContact O-N 2.68Å; D240-K243 WeakPolarHBondContact OD2-CE 3.48Å; D240-K243 IonicContact OD2-NZ 2.67Å; D240-K243 PolarHBondContact OD2-NZ 3.15Å; F241-K243 PolarHBondContact O-N 3.3Å
244S92Very high91.7Very high27 Ų2754 Ų5419%0.18926%0.258CS..  trans-113.5158.6176.4175.70000110.3E246 V249 D254S244-E246 VanDerWaalsContact C-N 3.28Å; S244-E246 WeakPolarHBondContact OG-CB 3.19Å; S244-E246 PolarHBondContact OG-N 2.73Å; S244-V249 WeakPolarHBondContact OG-CG2 3.44Å; S244-D254 VanDerWaalsContact CA-OD2 3.29Å; S244-D254 WeakPolarHBondContact CA-OD2 3.25Å; S244-D254 VanDerWaalsContact CB-OD1 3.23Å; S244-D254 WeakPolarHBondContact CB-OD1 3.46Å; S244-D254 PolarHBondContact OG-OD1 2.83Å
245Q85.4Confident92.2Very high124 Ų12453.8 Ų53.858%0.57926%0.256SS*.SBendtrans-73.5-22.7163.6-53.5-161.94800112.4V236 L238 D254V236-Q245 PolarHBondContact O-NE2 3.48Å; L238-Q245 HydrophobicContact CD1-CG 4.3Å; L238-Q245 HydrophobicContact CD2-CG 3.86Å; L238-Q245 HydrophobicContact CG-CG 3.93Å; Q245-D254 PolarHBondContact N-OD2 3.4Å
246E85.6Confident92.6Very high59 Ų5952.8 Ų52.828%0.27625%0.25SC..SBendtrans-85.3150.2-177-63.9-74.8-173.400112.3R135 S244 V249R135-E246 IonicContact CZ-OE1 2.75Å; R135-E246 IonicContact NE-OE1 2.96Å; R135-E246 PolarHBondContact NE-OE1 2.82Å; R135-E246 IonicContact NE-OE2 3.18Å; R135-E246 IonicContact NH2-OE1 2.68Å; R135-E246 PolarHBondContact NH2-OE1 2.86Å; S244-E246 VanDerWaalsContact C-N 3.28Å; S244-E246 WeakPolarHBondContact OG-CB 3.19Å; S244-E246 PolarHBondContact OG-N 2.73Å; E246-V249 HydrophobicContact CB-CG1 4Å; E246-V249 HydrophobicContact CB-CG2 4.17Å
247L85.4Confident92.9Very high134 Ų13450.8 Ų50.870%0.70224%0.238SC*.THydrogen-bonded Turntrans-94.1141.2-177.6-65177.3000112.4W136 V249W136-L247 WeakPolarHBondContact CZ2-O 3.34Å; W136-L247 PolarHBondContact NE1-O 2.92Å; L247-V249 VanDerWaalsContact C-N 3.32Å; L247-V249 PolarHBondContact O-N 3.1Å
248R85.2Confident93.2Very high191 Ų19150.6 Ų50.672%0.72124%0.236SC*.THydrogen-bonded Turntrans62.133.3178.5-45.3172.3-62.5175.34.1113.9W136W136-R248 VanDerWaalsContact CD2-NH2 3.32Å; W136-R248 VanDerWaalsContact CE2-NH2 3.32Å
249V90.9Very high93.3Very high33 Ų3348 Ų4820%0.222%0.224CC..  trans-104.1166.9169.9-58.40000111S244 E246 L247 Y253S244-V249 WeakPolarHBondContact OG-CG2 3.44Å; E246-V249 HydrophobicContact CB-CG1 4Å; E246-V249 HydrophobicContact CB-CG2 4.17Å; L247-V249 VanDerWaalsContact C-N 3.32Å; L247-V249 PolarHBondContact O-N 3.1Å; V249-Y253 HydrophobicContact CB-CD1 4.18Å; V249-Y253 HydrophobicContact CB-CD2 3.65Å; V249-Y253 HydrophobicContact CB-CE2 4.3Å; V249-Y253 HydrophobicContact CB-CG 3.59Å; V249-Y253 HydrophobicContact CG1-CD1 4.06Å; V249-Y253 HydrophobicContact CG1-CD2 3.83Å; V249-Y253 HydrophobicContact CG1-CE1 4.22Å; V249-Y253 HydrophobicContact CG1-CE2 3.97Å; V249-Y253 HydrophobicContact CG1-CG 3.88Å; V249-Y253 HydrophobicContact CG2-CD1 4.14Å; V249-Y253 HydrophobicContact CG2-CD2 4.34Å; V249-Y253 HydrophobicContact CG2-CG 3.76Å
250W92.6Very high93.4Very high96 Ų9647.4 Ų47.436%0.36422%0.22SC..  trans-83161-179.95075.7000113Y209 S213 G252 Y253Y209-W250 HydrophobicContact CD2-CB 4.19Å; Y209-W250 HydrophobicContact CD2-CG 4.19Å; S213-W250 WeakPolarHBondContact OG-CH2 3.26Å; S213-W250 WeakPolarHBondContact OG-CZ2 3.49Å; W250-G252 PolarHBondContact O-N 2.67Å; W250-Y253 HydrophobicContact CD2-CD2 4.22Å; W250-Y253 AromaticContact CE2-CD2 3.67Å; W250-Y253 HydrophobicContact CH2-CD2 4.38Å; W250-Y253 HydrophobicContact CH2-CE2 4.24Å; W250-Y253 AromaticContact CZ2-CD2 3.78Å; W250-Y253 HydrophobicContact CZ2-CD2 3.78Å; W250-Y253 AromaticContact CZ2-CE2 3.95Å; W250-Y253 HydrophobicContact CZ2-CE2 3.95Å; W250-Y253 AromaticContact NE1-CD2 3.8Å; W250-Y253 WeakPolarHBondContact O-CB 3.43Å; W250-Y253 PolarHBondContact O-N 3.09Å
251P95.9Very high93.4Very high33 Ų3354.5 Ų54.521%0.21425%0.252CS..THydrogen-bonded Turntrans-57.4130.9171.2-23.434.4000111.2E206 V208 Y209 R242E206-P251 HydrophobicContact CG-CG 4.4Å; V208-P251 CarbonylContact C-O 3.55Å; V208-P251 WeakPolarHBondContact CA-O 3.31Å; V208-P251 HydrophobicContact CG1-CB 4.43Å; V208-P251 WeakPolarHBondContact CG1-O 3.25Å; V208-P251 HydrophobicContact CG2-CB 4.28Å; Y209-P251 PolarHBondContact N-O 2.97Å; R242-P251 HydrophobicContact CB-CB 4.36Å; R242-P251 VanDerWaalsContact O-CA 3.28Å; R242-P251 WeakPolarHBondContact O-CA 3.3Å; R242-P251 WeakPolarHBondContact O-CB 3.4Å
252G94.3Very high93.3Very high0 Ų057.6 Ų57.60%027%0.274CS..THydrogen-bonded Turntrans100.9-12.6-176.800000115.2V208 Y209 F241 W250 D254 Y255V208-G252 VanDerWaalsContact CG1-CA 3.47Å; Y209-G252 CarbonylContact O-C 3.54Å; F241-G252 WeakPolarHBondContact O-CA 3.41Å; F241-G252 PolarHBondContact O-N 3.33Å; W250-G252 PolarHBondContact O-N 2.67Å; G252-D254 VanDerWaalsContact C-N 3.33Å; G252-D254 PolarHBondContact O-N 3.19Å; G252-D254 VanDerWaalsContact O-N 3.08Å; G252-Y255 PolarHBondContact O-N 2.89Å
253Y96.8Very high93.4Very high1 Ų155.9 Ų55.90%0.00427%0.269CS..THydrogen-bonded Turntrans-49-43.9-166.2-172.4-90.5000115.4R135 S213 Q230 V249 W250 Y255R135-Y253 WeakPolarHBondContact CB-OH 3.44Å; R135-Y253 WeakPolarHBondContact CD-OH 3.47Å; R135-Y253 VanDerWaalsContact CG-OH 3.32Å; R135-Y253 WeakPolarHBondContact CG-OH 3.4Å; S213-Y253 WeakPolarHBondContact OG-CE2 3.36Å; Q230-Y253 PolarHBondContact NE2-O 2.9Å; Q230-Y253 PolarHBondContact OE1-O 3Å; V249-Y253 HydrophobicContact CB-CD1 4.18Å; V249-Y253 HydrophobicContact CB-CD2 3.65Å; V249-Y253 HydrophobicContact CB-CE2 4.3Å; V249-Y253 HydrophobicContact CB-CG 3.59Å; V249-Y253 HydrophobicContact CG1-CD1 4.06Å; V249-Y253 HydrophobicContact CG1-CD2 3.83Å; V249-Y253 HydrophobicContact CG1-CE1 4.22Å; V249-Y253 HydrophobicContact CG1-CE2 3.97Å; V249-Y253 HydrophobicContact CG1-CG 3.88Å; V249-Y253 HydrophobicContact CG2-CD1 4.14Å; V249-Y253 HydrophobicContact CG2-CD2 4.34Å; V249-Y253 HydrophobicContact CG2-CG 3.76Å; W250-Y253 HydrophobicContact CD2-CD2 4.22Å; W250-Y253 AromaticContact CE2-CD2 3.67Å; W250-Y253 HydrophobicContact CH2-CD2 4.38Å; W250-Y253 HydrophobicContact CH2-CE2 4.24Å; W250-Y253 AromaticContact CZ2-CD2 3.78Å; W250-Y253 HydrophobicContact CZ2-CD2 3.78Å; W250-Y253 AromaticContact CZ2-CE2 3.95Å; W250-Y253 HydrophobicContact CZ2-CE2 3.95Å; W250-Y253 AromaticContact NE1-CD2 3.8Å; W250-Y253 WeakPolarHBondContact O-CB 3.43Å; W250-Y253 PolarHBondContact O-N 3.09Å; Y253-Y255 PolarHBondContact O-N 3Å
254D95.7Very high93.4Very high4 Ų456.8 Ų56.82%0.02129%0.29CS..THydrogen-bonded Turntrans-72.53.4-176.1-60.9-1.8000114.3S244 Q245 G252 S360S244-D254 VanDerWaalsContact CA-OD2 3.29Å; S244-D254 WeakPolarHBondContact CA-OD2 3.25Å; S244-D254 VanDerWaalsContact CB-OD1 3.23Å; S244-D254 WeakPolarHBondContact CB-OD1 3.46Å; S244-D254 PolarHBondContact OG-OD1 2.83Å; Q245-D254 PolarHBondContact N-OD2 3.4Å; G252-D254 VanDerWaalsContact C-N 3.33Å; G252-D254 PolarHBondContact O-N 3.19Å; G252-D254 VanDerWaalsContact O-N 3.08Å; D254-S360 WeakPolarHBondContact O-CA 3.29Å; D254-S360 WeakPolarHBondContact O-CB 3.48Å
255Y97.8Very high93.4Very high1 Ų158.2 Ų58.20%0.00430%0.3CS..  trans-136.2127.8-171.1-75.8-85.2000112.9L210 G237 L238 F241 G252 Y253 N288 A331 L358 F359 S360L210-Y255 CarbonylContact C-O 3.57Å; L210-Y255 WeakPolarHBondContact CA-O 3.32Å; L210-Y255 WeakPolarHBondContact CB-O 3.32Å; G237-Y255 PolarHBondContact O-OH 3.01Å; G237-Y255 VanDerWaalsContact O-OH 3.13Å; L238-Y255 VanDerWaalsContact O-CE2 3.3Å; L238-Y255 WeakPolarHBondContact O-CE2 3.25Å; L238-Y255 PolarHBondContact O-OH 2.93Å; F241-Y255 HydrophobicContact CB-CD2 3.52Å; F241-Y255 HydrophobicContact CB-CE2 3.57Å; F241-Y255 HydrophobicContact CB-CG 4.2Å; G252-Y255 PolarHBondContact O-N 2.89Å; Y253-Y255 PolarHBondContact O-N 3Å; Y255-N288 HydrophobicContact CD1-CB 4.3Å; Y255-N288 HydrophobicContact CE1-CB 3.61Å; Y255-N288 PolarHBondContact OH-ND2 2.84Å; Y255-A331 WeakPolarHBondContact OH-CB 3.23Å; Y255-L358 HydrophobicContact CD1-CB 3.77Å; Y255-L358 HydrophobicContact CE1-CB 4.41Å; Y255-L358 HydrophobicContact CG-CB 4.29Å; Y255-F359 WeakPolarHBondContact CA-O 3.43Å; Y255-S360 WeakPolarHBondContact CD1-OG 3.46Å; Y255-S360 WeakPolarHBondContact CE1-OG 3.3Å
256V98.4Very high93.9Very high2 Ų253.5 Ų53.51%0.01229%0.285CS..EExtended strand (participates in β ladder)trans-89.3131.4162.7-163.40000108.4L210 D212 Q230 L231 W258 F359L210-V256 CarbonylContact O-C 3.55Å; L210-V256 WeakPolarHBondContact O-CA 3.09Å; D212-V256 HydrophobicContact CB-CG1 4.26Å; D212-V256 HydrophobicContact CB-CG2 3.72Å; D212-V256 WeakPolarHBondContact OD2-CG2 3.21Å; Q230-V256 HydrophobicContact CB-CG2 4.36Å; L231-V256 HydrophobicContact CD1-CB 4.32Å; L231-V256 HydrophobicContact CD1-CG2 4.32Å; L231-V256 HydrophobicContact CD2-CB 3.99Å; L231-V256 HydrophobicContact CD2-CG2 3.85Å; L231-V256 HydrophobicContact CG-CB 4.17Å; L231-V256 HydrophobicContact CG-CG2 3.76Å; V256-W258 HydrophobicContact CB-CH2 3.92Å; V256-W258 HydrophobicContact CB-CZ2 4.18Å; V256-W258 HydrophobicContact CG1-CH2 3.74Å; V256-W258 HydrophobicContact CG1-CZ2 3.47Å; V256-W258 VanDerWaalsContact CG1-CZ2 3.47Å; V256-W258 WeakPolarHBondContact O-CZ3 3.5Å; V256-F359 PolarHBondContact N-O 3.46Å; V256-F359 PolarHBondContact O-N 3.38Å
257G97.7Very high94.4Very high0 Ų053.6 Ų53.60%028%0.283CS..EExtended strand (participates in β ladder)trans-148.2150.2-167.400000115.8G199 Q200 L210 L357G199-G257 CarbonylContact C-O 3.37Å; G199-G257 WeakPolarHBondContact CA-O 3.25Å; Q200-G257 PolarHBondContact N-O 3.36Å; L210-G257 PolarHBondContact O-N 2.74Å; G257-L357 CarbonylContact C-O 3.6Å; G257-L357 WeakPolarHBondContact CA-O 3.4Å
258W98.2Very high95Very high0 Ų047.2 Ų47.20%025%0.25CC..EExtended strand (participates in β ladder)trans-137.2146.6-174.3-51.7-88.1000111.2P197 L231 V256 F263 V268 M270 F352 W356 L357 F359P197-W258 PolarHBondContact O-NE1 2.75Å; L231-W258 HydrophobicContact CD1-CH2 4.2Å; V256-W258 HydrophobicContact CB-CH2 3.92Å; V256-W258 HydrophobicContact CB-CZ2 4.18Å; V256-W258 HydrophobicContact CG1-CH2 3.74Å; V256-W258 HydrophobicContact CG1-CZ2 3.47Å; V256-W258 VanDerWaalsContact CG1-CZ2 3.47Å; V256-W258 WeakPolarHBondContact O-CZ3 3.5Å; W258-F263 HydrophobicContact CB-CE2 3.86Å; W258-F263 HydrophobicContact CG-CE2 4.28Å; W258-F263 HydrophobicContact CG-CZ 4.49Å; W258-V268 HydrophobicContact CB-CG2 3.78Å; W258-V268 HydrophobicContact CD2-CG1 4Å; W258-V268 HydrophobicContact CD2-CG2 3.9Å; W258-V268 HydrophobicContact CE3-CG1 4.24Å; W258-V268 HydrophobicContact CE3-CG2 3.98Å; W258-V268 HydrophobicContact CG-CG1 4.41Å; W258-V268 HydrophobicContact CG-CG2 3.83Å; W258-M270 HydrophobicContact CH2-CE 3.19Å; W258-M270 HydrophobicContact CZ2-CE 3.6Å; W258-M270 HydrophobicContact CZ3-CE 3.84Å; W258-F352 HydrophobicContact CB-CZ 4.2Å; W258-F352 WeakPolarHBondContact O-CE1 3.29Å; W258-W356 WeakPolarHBondContact O-CA 3.32Å; W258-L357 HydrophobicContact CE3-CB 4.49Å; W258-L357 PolarHBondContact N-O 2.92Å; W258-L357 PolarHBondContact O-N 3.38Å; W258-F359 HydrophobicContact CH2-CD2 4.1Å; W258-F359 AromaticContact CZ3-CD2 3.63Å; W258-F359 HydrophobicContact CZ3-CD2 3.63Å; W258-F359 AromaticContact CZ3-CE2 4Å; W258-F359 HydrophobicContact CZ3-CE2 4Å; W258-F359 HydrophobicContact CZ3-CG 4.19Å
259S97.3Very high95.6Very high13 Ų1341.2 Ų41.29%0.09123%0.23CC..EExtended strand (participates in β ladder)trans-96.1134.3176.763.90000111.8Q200 H261 S262 F263 P355Q200-S259 PolarHBondContact OE1-OG 2.86Å; S259-H261 PolarHBondContact O-N 3.05Å; S259-H261 VanDerWaalsContact O-N 3.16Å; S259-S262 WeakPolarHBondContact O-CB 3.47Å; S259-S262 PolarHBondContact O-N 2.94Å; S259-S262 PolarHBondContact OG-OG 2.99Å; S259-F263 WeakPolarHBondContact O-CD2 3.3Å; S259-P355 WeakPolarHBondContact CA-O 3.22Å
260N96.6Very high95.9Very high60 Ų6039.7 Ų39.732%0.32122%0.221SC..G310 helixtrans-56-35.2178.2-17329.2000112.1S262 F263 F352 P355N260-S262 PolarHBondContact O-N 2.87Å; N260-S262 VanDerWaalsContact O-N 3.14Å; N260-F263 PolarHBondContact O-N 3.24Å; N260-F352 HydrophobicContact CB-CB 4.04Å; N260-F352 HydrophobicContact CB-CD1 3.67Å; N260-F352 HydrophobicContact CB-CD2 4.07Å; N260-F352 HydrophobicContact CB-CE1 4.11Å; N260-F352 HydrophobicContact CB-CE2 4.48Å; N260-F352 HydrophobicContact CB-CG 3.67Å; N260-F352 HydrophobicContact CB-CZ 4.5Å; N260-F352 VanDerWaalsContact OD1-CD2 3.26Å; N260-F352 WeakPolarHBondContact OD1-CD2 3.21Å; N260-F352 WeakPolarHBondContact OD1-CG 3.39Å; N260-P355 PolarHBondContact N-O 2.94Å
261H94.1Very high96.1Very high173 Ų17337.9 Ų37.980%0.80122%0.216SC*.G310 helixtrans-61.1-21.4178-64.5-71.2000114.3S259S259-H261 PolarHBondContact O-N 3.05Å; S259-H261 VanDerWaalsContact O-N 3.16Å
262S93Very high96.2Very high64 Ų6436.4 Ų36.445%0.44821%0.206SC..G310 helixtrans-84.4-13.7177.1-61.90000113.6Q200 S259 N260Q200-S262 VanDerWaalsContact NE2-CB 3.32Å; Q200-S262 PolarHBondContact NE2-OG 3.02Å; Q200-S262 PolarHBondContact OE1-OG 2.86Å; S259-S262 WeakPolarHBondContact O-CB 3.47Å; S259-S262 PolarHBondContact O-N 2.94Å; S259-S262 PolarHBondContact OG-OG 2.99Å; N260-S262 PolarHBondContact O-N 2.87Å; N260-S262 VanDerWaalsContact O-N 3.14Å
263F95.1Very high96.3Very high38 Ų3839 Ų3917%0.16722%0.218CC..  trans-123.490-170.8-67.9-91.2000110.7P197 W258 S259 N260 S265 G266 F352P197-F263 HydrophobicContact CB-CE1 4.09Å; P197-F263 HydrophobicContact CB-CZ 3.74Å; P197-F263 HydrophobicContact CG-CE1 3.77Å; P197-F263 HydrophobicContact CG-CZ 3.86Å; W258-F263 HydrophobicContact CB-CE2 3.86Å; W258-F263 HydrophobicContact CG-CE2 4.28Å; W258-F263 HydrophobicContact CG-CZ 4.49Å; S259-F263 WeakPolarHBondContact O-CD2 3.3Å; N260-F263 PolarHBondContact O-N 3.24Å; F263-S265 PolarHBondContact O-N 2.65Å; F263-G266 PolarHBondContact O-N 3.21Å; F263-F352 HydrophobicContact CB-CE2 3.88Å; F263-F352 HydrophobicContact CD2-CE2 4.14Å; F263-F352 AromaticContact CD2-CZ 3.98Å; F263-F352 HydrophobicContact CD2-CZ 3.98Å; F263-F352 HydrophobicContact CG-CE2 4.16Å; F263-F352 HydrophobicContact CG-CZ 4.45Å
264S92.7Very high96.2Very high140 Ų14039 Ų3998%0.97922%0.218SC*.THydrogen-bonded Turntrans-59.8-13.3175.356.20000114.3
265S93.1Very high96Very high56 Ų5640.8 Ų40.839%0.39223%0.228SC..THydrogen-bonded Turntrans-71.4-22.3170.355.90000114.4F263 Y267F263-S265 PolarHBondContact O-N 2.65Å; S265-Y267 VanDerWaalsContact C-N 3.29Å; S265-Y267 WeakPolarHBondContact O-CD1 3.09Å; S265-Y267 WeakPolarHBondContact O-CE1 3.4Å; S265-Y267 PolarHBondContact OG-N 2.87Å; S265-Y267 PolarHBondContact OG-O 2.59Å
266G94.7Very high95.7Very high26 Ų2646.5 Ų46.527%0.26825%0.25SC..SBendtrans73.514.3-171.500000114.7F263 F352F263-G266 PolarHBondContact O-N 3.21Å; G266-F352 PolarHBondContact O-N 3.43Å
267Y96.8Very high95.5Very high60 Ų6048.4 Ų48.424%0.23526%0.259CS..EExtended strand (participates in β ladder)trans-149.5152.3174.754.7-95.6000113.7S265 E269 R349 F350 L351S265-Y267 VanDerWaalsContact C-N 3.29Å; S265-Y267 WeakPolarHBondContact O-CD1 3.09Å; S265-Y267 WeakPolarHBondContact O-CE1 3.4Å; S265-Y267 PolarHBondContact OG-N 2.87Å; S265-Y267 PolarHBondContact OG-O 2.59Å; Y267-E269 HydrophobicContact CD2-CB 4.16Å; Y267-E269 HydrophobicContact CE2-CB 4.14Å; Y267-R349 HydrophobicContact CD2-CB 3.86Å; Y267-R349 HydrophobicContact CD2-CG 3.71Å; Y267-R349 HydrophobicContact CE2-CB 4.4Å; Y267-R349 HydrophobicContact CE2-CG 3.79Å; Y267-R349 HydrophobicContact CG-CB 4.08Å; Y267-R349 HydrophobicContact CG-CG 4.36Å; Y267-F350 WeakPolarHBondContact CA-O 3.43Å; Y267-F350 VanDerWaalsContact CB-O 3.29Å; Y267-F350 WeakPolarHBondContact CB-O 3.38Å; Y267-L351 HydrophobicContact CD1-CD2 4.36Å
268V97.6Very high95.4Very high0 Ų048.9 Ų48.90%026%0.261CS..EExtended strand (participates in β ladder)trans-84130.6160.2-177.20000108P197 W258 M270 R349 F350 F352 L357P197-V268 HydrophobicContact CG-CG1 4.2Å; W258-V268 HydrophobicContact CB-CG2 3.78Å; W258-V268 HydrophobicContact CD2-CG1 4Å; W258-V268 HydrophobicContact CD2-CG2 3.9Å; W258-V268 HydrophobicContact CE3-CG1 4.24Å; W258-V268 HydrophobicContact CE3-CG2 3.98Å; W258-V268 HydrophobicContact CG-CG1 4.41Å; W258-V268 HydrophobicContact CG-CG2 3.83Å; V268-M270 HydrophobicContact CG1-CE 4.09Å; V268-M270 HydrophobicContact CG1-CG 4.42Å; V268-R349 CarbonylContact O-C 3.3Å; V268-R349 WeakPolarHBondContact O-CA 3.41Å; V268-F350 PolarHBondContact N-O 3.26Å; V268-F350 PolarHBondContact O-N 2.94Å; V268-F352 HydrophobicContact CG2-CE1 4.34Å; V268-F352 HydrophobicContact CG2-CE2 3.96Å; V268-F352 HydrophobicContact CG2-CZ 3.54Å; V268-L357 HydrophobicContact CG2-CD1 4.12Å
269E97.5Very high95.2Very high66 Ų6649.8 Ų49.831%0.30827%0.269SS..EExtended strand (participates in β ladder)trans-106.5138.8173.9-175.1169.681.800110P197 Y267 Q347 C348 R349P197-E269 WeakPolarHBondContact CD-O 3.5Å; Y267-E269 HydrophobicContact CD2-CB 4.16Å; Y267-E269 HydrophobicContact CE2-CB 4.14Å; E269-Q347 HydrophobicContact CG-CG 4.04Å; E269-C348 WeakPolarHBondContact CA-O 3.26Å; E269-R349 HydrophobicContact CB-CG 4.33Å; E269-R349 HydrophobicContact CG-CG 4.14Å; E269-R349 IonicContact OE2-CZ 3.46Å; E269-R349 IonicContact OE2-NE 3.77Å; E269-R349 PolarHBondContact OE2-NE 2.94Å; E269-R349 IonicContact OE2-NH2 3.16Å; E269-R349 PolarHBondContact OE2-NH2 3.23Å
270M98.3Very high95.1Very high1 Ų149.2 Ų49.21%0.00526%0.264CS..EExtended strand (participates in β ladder)trans-136144.4176.2-63.2-179.8176.700110.9T195 A196 L231 W258 V268 F272 Q347 C348 F350 F359 I362T195-M270 CarbonylContact O-C 3.49Å; T195-M270 WeakPolarHBondContact O-CA 3.24Å; T195-M270 WeakPolarHBondContact O-CB 3.44Å; A196-M270 HydrophobicContact CB-CE 4.12Å; A196-M270 HydrophobicContact CB-CG 3.97Å; A196-M270 HydrophobicContact CB-SD 4.44Å; L231-M270 HydrophobicContact CD1-CE 3.98Å; W258-M270 HydrophobicContact CH2-CE 3.19Å; W258-M270 HydrophobicContact CZ2-CE 3.6Å; W258-M270 HydrophobicContact CZ3-CE 3.84Å; V268-M270 HydrophobicContact CG1-CE 4.09Å; V268-M270 HydrophobicContact CG1-CG 4.42Å; M270-F272 HydrophobicContact CB-CD2 4.44Å; M270-F272 HydrophobicContact CB-CE2 3.59Å; M270-F272 HydrophobicContact CB-CZ 3.78Å; M270-F272 HydrophobicContact CG-CZ 4.44Å; M270-F272 HydrophobicContact SD-CE2 4.46Å; M270-F272 HydrophobicContact SD-CZ 3.77Å; M270-Q347 CarbonylContact O-C 3.54Å; M270-Q347 WeakPolarHBondContact O-CA 3.44Å; M270-C348 PolarHBondContact N-O 2.97Å; M270-C348 PolarHBondContact O-N 3.32Å; M270-F350 HydrophobicContact CB-CE2 4.32Å; M270-F350 HydrophobicContact CG-CE2 4.14Å; M270-F350 HydrophobicContact SD-CD2 4.38Å; M270-F350 HydrophobicContact SD-CE2 3.77Å; M270-F359 HydrophobicContact CE-CD2 3.99Å; M270-F359 HydrophobicContact CE-CE2 4.11Å; M270-I362 HydrophobicContact CE-CD1 4.46Å; M270-I362 HydrophobicContact SD-CD1 3.81Å
271E97.4Very high94.9Very high57 Ų5751.1 Ų51.127%0.26627%0.271SS..EExtended strand (participates in β ladder)trans-112.7141.8167.6-62.6-153.9-179.300111.6Y194 T195 R306 L346 Q347Y194-E271 CarbonylContact C-O 3.6Å; Y194-E271 VanDerWaalsContact CA-O 3.25Å; Y194-E271 WeakPolarHBondContact CA-O 3.18Å; T195-E271 PolarHBondContact N-O 2.54Å; T195-E271 PolarHBondContact O-N 2.88Å; E271-R306 IonicContact OE2-NH2 3.05Å; E271-R306 PolarHBondContact OE2-NH2 3.32Å; E271-L346 CarbonylContact C-O 3.55Å; E271-L346 VanDerWaalsContact CA-O 3.28Å; E271-L346 WeakPolarHBondContact CA-O 3.41Å; E271-Q347 HydrophobicContact CG-CB 3.97Å; E271-Q347 HydrophobicContact CG-CG 4.03Å; E271-Q347 PolarHBondContact OE1-NE2 2.91Å
272F97.7Very high94.9Very high2 Ų243.4 Ų43.41%0.00924%0.238CC..EExtended strand (participates in β ladder)trans-126.5123.8-177.1-58.9-91.6000109.3L191 Y194 M270 F274 F345 L346 C348 I362 F364L191-F272 HydrophobicContact CD1-CB 3.65Å; L191-F272 HydrophobicContact CD1-CD1 3.82Å; L191-F272 HydrophobicContact CD1-CG 4.24Å; L191-F272 HydrophobicContact CD2-CD1 4.28Å; Y194-F272 HydrophobicContact CG-CE1 4.49Å; M270-F272 HydrophobicContact CB-CD2 4.44Å; M270-F272 HydrophobicContact CB-CE2 3.59Å; M270-F272 HydrophobicContact CB-CZ 3.78Å; M270-F272 HydrophobicContact CG-CZ 4.44Å; M270-F272 HydrophobicContact SD-CE2 4.46Å; M270-F272 HydrophobicContact SD-CZ 3.77Å; F272-F274 HydrophobicContact CB-CE2 3.63Å; F272-F274 HydrophobicContact CB-CZ 3.97Å; F272-F345 VanDerWaalsContact O-CA 3.31Å; F272-F345 WeakPolarHBondContact O-CA 3.35Å; F272-L346 HydrophobicContact CB-CB 4.32Å; F272-L346 HydrophobicContact CD2-CB 4.42Å; F272-L346 PolarHBondContact N-O 3.44Å; F272-L346 PolarHBondContact O-N 3.41Å; F272-C348 HydrophobicContact CE2-CB 4.24Å; F272-I362 HydrophobicContact CE1-CD1 4.14Å; F272-I362 HydrophobicContact CE1-CG2 3.98Å; F272-I362 HydrophobicContact CZ-CD1 3.93Å; F272-I362 HydrophobicContact CZ-CG2 4.16Å; F272-F364 HydrophobicContact CB-CZ 4.24Å; F272-F364 AromaticContact CD1-CE2 3.64Å; F272-F364 HydrophobicContact CD1-CE2 3.64Å; F272-F364 AromaticContact CD1-CZ 3.49Å; F272-F364 HydrophobicContact CD1-CZ 3.49Å; F272-F364 VanDerWaalsContact CD1-CZ 3.49Å; F272-F364 AromaticContact CD2-CZ 3.97Å; F272-F364 HydrophobicContact CD2-CZ 3.97Å; F272-F364 AromaticContact CE1-CE2 3.96Å; F272-F364 HydrophobicContact CE1-CE2 3.96Å; F272-F364 AromaticContact CE1-CZ 3.72Å; F272-F364 HydrophobicContact CE1-CZ 3.72Å; F272-F364 HydrophobicContact CE2-CZ 4.17Å; F272-F364 HydrophobicContact CG-CE2 4.15Å; F272-F364 AromaticContact CG-CZ 3.63Å; F272-F364 HydrophobicContact CG-CZ 3.63Å; F272-F364 HydrophobicContact CZ-CZ 4.06Å
273E95.9Very high95Very high55 Ų5540.4 Ų40.426%0.25722%0.217SC..EExtended strand (participates in β ladder)trans-106.8134.8174177.4172.6175.800110.8L192 S193 R344 F345L192-E273 HydrophobicContact CD1-CG 4.3Å; L192-E273 PolarHBondContact N-O 2.88Å; S193-E273 PolarHBondContact O-N 2.94Å; E273-R344 IonicContact OE1-CZ 2.75Å; E273-R344 IonicContact OE1-NE 3.38Å; E273-R344 IonicContact OE1-NH2 2.69Å; E273-R344 PolarHBondContact OE1-NH2 3.31Å; E273-F345 HydrophobicContact CB-CD1 3.95Å; E273-F345 HydrophobicContact CB-CE1 3.85Å; E273-F345 HydrophobicContact CG-CD1 4.02Å; E273-F345 HydrophobicContact CG-CE1 3.51Å; E273-F345 HydrophobicContact CG-CZ 3.99Å; E273-F345 WeakPolarHBondContact OE2-CE1 3.5Å
274F95.3Very high95Very high0 Ų039.1 Ų39.10%021%0.211CC..EExtended strand (participates in β ladder)trans-113.4160-179-61.2-95.8000112.8G190 L191 F272 R276 F280 R344 L346 F364G190-F274 CarbonylContact O-C 3.51Å; G190-F274 WeakPolarHBondContact O-CA 3.34Å; L191-F274 HydrophobicContact CB-CD1 4.22Å; L191-F274 HydrophobicContact CB-CE1 3.99Å; L191-F274 HydrophobicContact CD1-CD1 4.35Å; L191-F274 HydrophobicContact CD1-CE1 3.87Å; L191-F274 HydrophobicContact CD1-CE2 4.15Å; L191-F274 HydrophobicContact CD1-CZ 3.76Å; F272-F274 HydrophobicContact CB-CE2 3.63Å; F272-F274 HydrophobicContact CB-CZ 3.97Å; F274-R276 VanDerWaalsContact C-N 3.3Å; F274-R276 PolarHBondContact O-N 2.89Å; F274-F280 HydrophobicContact CB-CZ 4.49Å; F274-F280 HydrophobicContact CD1-CE1 4.01Å; F274-F280 AromaticContact CD1-CZ 3.95Å; F274-F280 HydrophobicContact CD1-CZ 3.95Å; F274-F280 HydrophobicContact CD2-CE1 4.11Å; F274-F280 AromaticContact CD2-CZ 3.53Å; F274-F280 HydrophobicContact CD2-CZ 3.53Å; F274-F280 AromaticContact CE1-CE1 3.69Å; F274-F280 HydrophobicContact CE1-CE1 3.69Å; F274-F280 HydrophobicContact CE1-CZ 4.04Å; F274-F280 AromaticContact CE2-CE1 3.79Å; F274-F280 HydrophobicContact CE2-CE1 3.79Å; F274-F280 AromaticContact CE2-CZ 3.63Å; F274-F280 HydrophobicContact CE2-CZ 3.63Å; F274-F280 HydrophobicContact CG-CE1 4.23Å; F274-F280 AromaticContact CG-CZ 3.71Å; F274-F280 HydrophobicContact CG-CZ 3.71Å; F274-F280 AromaticContact CZ-CE1 3.58Å; F274-F280 HydrophobicContact CZ-CE1 3.58Å; F274-F280 AromaticContact CZ-CZ 3.89Å; F274-F280 HydrophobicContact CZ-CZ 3.89Å; F274-R344 WeakPolarHBondContact CD2-O 3.12Å; F274-R344 PolarHBondContact N-O 3.18Å; F274-R344 VanDerWaalsContact O-CG 3.28Å; F274-R344 WeakPolarHBondContact O-CG 3.44Å; F274-R344 PolarHBondContact O-NE 3.17Å; F274-L346 HydrophobicContact CE2-CB 4.5Å; F274-L346 HydrophobicContact CE2-CD1 3.87Å; F274-L346 HydrophobicContact CE2-CG 3.96Å; F274-L346 HydrophobicContact CZ-CD1 4.14Å; F274-F364 HydrophobicContact CE1-CB 3.9Å; F274-F364 HydrophobicContact CE1-CD1 4.33Å; F274-F364 AromaticContact CE1-CD2 3.64Å; F274-F364 HydrophobicContact CE1-CD2 3.64Å; F274-F364 HydrophobicContact CE1-CE2 4.26Å; F274-F364 AromaticContact CE1-CG 3.69Å; F274-F364 HydrophobicContact CE1-CG 3.69Å; F274-F364 HydrophobicContact CZ-CB 4.19Å; F274-F364 AromaticContact CZ-CD1 3.75Å; F274-F364 HydrophobicContact CZ-CD1 3.75Å; F274-F364 AromaticContact CZ-CD2 3.54Å; F274-F364 HydrophobicContact CZ-CD2 3.54Å; F274-F364 AromaticContact CZ-CE1 3.96Å; F274-F364 HydrophobicContact CZ-CE1 3.96Å; F274-F364 AromaticContact CZ-CE2 3.77Å; F274-F364 HydrophobicContact CZ-CE2 3.77Å; F274-F364 AromaticContact CZ-CG 3.54Å; F274-F364 HydrophobicContact CZ-CG 3.54Å; F274-F364 AromaticContact CZ-CZ 3.98Å; F274-F364 HydrophobicContact CZ-CZ 3.98Å
275D91.5Very high95.1Very high42 Ų4232.6 Ų32.623%0.22517%0.165CC..EExtended strand (participates in β ladder)trans-63.3-32.2-176.381.8-52.6000114L94 G190 L192 R278L94-D275 HydrophobicContact CD1-CB 3.96Å; G190-D275 PolarHBondContact O-N 2.87Å; L192-D275 HydrophobicContact CD2-CB 4.48Å; L192-D275 HydrophobicContact CG-CB 4.3Å; D275-R278 IonicContact OD1-CZ 3.86Å; D275-R278 VanDerWaalsContact OD1-CZ 3.3Å; D275-R278 IonicContact OD1-NE 3.65Å; D275-R278 PolarHBondContact OD1-NE 3Å; D275-R278 IonicContact OD1-NH2 2.71Å; D275-R278 PolarHBondContact OD1-NH2 2.75Å
276R91.8Very high95.2Very high122 Ų12230.6 Ų30.646%0.4615%0.15SC..EExtended strand (participates in β ladder)trans-143.3170.7-172.1-69.6169.2-151.2-114.5-8.6111.1F274 R278 V368F274-R276 VanDerWaalsContact C-N 3.3Å; F274-R276 PolarHBondContact O-N 2.89Å; R276-R278 PolarHBondContact O-N 2.96Å; R276-V368 HydrophobicContact CB-CG1 4.17Å; R276-V368 HydrophobicContact CG-CG1 4.45Å
277L93.8Very high95.2Very high41 Ų4129.3 Ų29.322%0.21514%0.137CC..EExtended strand (participates in β ladder)trans-64.8126.2161.5-80.5161.6000109.3R307 V342 A343 R344 V369L277-R307 HydrophobicContact CD2-CB 3.92Å; L277-R307 HydrophobicContact CD2-CG 4Å; L277-V342 HydrophobicContact CB-CG1 4.5Å; L277-V342 HydrophobicContact CD2-CG1 4.15Å; L277-A343 CarbonylContact C-O 3.26Å; L277-A343 WeakPolarHBondContact CA-O 3.41Å; L277-R344 HydrophobicContact CD2-CB 4.38Å; L277-V369 HydrophobicContact CB-CB 4.43Å; L277-V369 PolarHBondContact O-N 2.93Å
278R94.4Very high95.2Very high11 Ų1126.5 Ų26.54%0.04213%0.126CC..EExtended strand (participates in β ladder)trans-135.3141.5-173.6-77.8166.3174.2-92.94.1111R188 D189 G190 D275 R276 F280 V342 A343 S366 D367 V368R188-R278 PolarHBondContact O-NH1 2.86Å; R188-R278 PolarHBondContact O-NH2 3.22Å; D189-R278 PolarHBondContact O-NH1 2.95Å; G190-R278 VanDerWaalsContact CA-NH2 3.33Å; D275-R278 IonicContact OD1-CZ 3.86Å; D275-R278 VanDerWaalsContact OD1-CZ 3.3Å; D275-R278 IonicContact OD1-NE 3.65Å; D275-R278 PolarHBondContact OD1-NE 3Å; D275-R278 IonicContact OD1-NH2 2.71Å; D275-R278 PolarHBondContact OD1-NH2 2.75Å; R276-R278 PolarHBondContact O-N 2.96Å; R278-F280 HydrophobicContact CB-CD2 4.39Å; R278-F280 HydrophobicContact CB-CE1 4.48Å; R278-F280 HydrophobicContact CB-CE2 3.75Å; R278-F280 HydrophobicContact CB-CZ 3.8Å; R278-F280 VanDerWaalsContact O-CD2 3.31Å; R278-F280 WeakPolarHBondContact O-CD2 3.42Å; R278-F280 WeakPolarHBondContact O-CE2 3.29Å; R278-V342 CarbonylContact O-C 3.52Å; R278-V342 VanDerWaalsContact O-CA 3.29Å; R278-V342 WeakPolarHBondContact O-CA 3.37Å; R278-A343 PolarHBondContact N-O 2.73Å; R278-A343 PolarHBondContact O-N 2.63Å; R278-S366 PolarHBondContact NH1-OG 2.71Å; R278-D367 CarbonylContact C-O 3.5Å; R278-D367 WeakPolarHBondContact CA-O 3.32Å; R278-V368 HydrophobicContact CG-CG2 4.26Å
279A94.8Very high95.1Very high19 Ų1926.7 Ų26.716%0.15713%0.127CC..EExtended strand (participates in β ladder)trans-89.3109172.100000108.7Q281 V342 S366 D367 V369A279-Q281 PolarHBondContact O-N 3.05Å; A279-V342 HydrophobicContact CB-CG2 4.15Å; A279-S366 VanDerWaalsContact O-CA 3.22Å; A279-S366 WeakPolarHBondContact O-CA 3.13Å; A279-S366 WeakPolarHBondContact O-CB 3.39Å; A279-D367 PolarHBondContact N-O 2.85Å; A279-D367 PolarHBondContact O-N 2.96Å; A279-D367 VanDerWaalsContact O-N 3.08Å; A279-V369 HydrophobicContact CB-CG2 4.05Å
280F94.6Very high94.9Very high0 Ų024.9 Ų24.90%012%0.119CC..EExtended strand (participates in β ladder)trans-86.7109.1-172.7-71-85.6000111.4F274 R278 F305 L338 G339 G340 R341 A343 L346 F364F274-F280 HydrophobicContact CB-CZ 4.49Å; F274-F280 HydrophobicContact CD1-CE1 4.01Å; F274-F280 AromaticContact CD1-CZ 3.95Å; F274-F280 HydrophobicContact CD1-CZ 3.95Å; F274-F280 HydrophobicContact CD2-CE1 4.11Å; F274-F280 AromaticContact CD2-CZ 3.53Å; F274-F280 HydrophobicContact CD2-CZ 3.53Å; F274-F280 AromaticContact CE1-CE1 3.69Å; F274-F280 HydrophobicContact CE1-CE1 3.69Å; F274-F280 HydrophobicContact CE1-CZ 4.04Å; F274-F280 AromaticContact CE2-CE1 3.79Å; F274-F280 HydrophobicContact CE2-CE1 3.79Å; F274-F280 AromaticContact CE2-CZ 3.63Å; F274-F280 HydrophobicContact CE2-CZ 3.63Å; F274-F280 HydrophobicContact CG-CE1 4.23Å; F274-F280 AromaticContact CG-CZ 3.71Å; F274-F280 HydrophobicContact CG-CZ 3.71Å; F274-F280 AromaticContact CZ-CE1 3.58Å; F274-F280 HydrophobicContact CZ-CE1 3.58Å; F274-F280 AromaticContact CZ-CZ 3.89Å; F274-F280 HydrophobicContact CZ-CZ 3.89Å; R278-F280 HydrophobicContact CB-CD2 4.39Å; R278-F280 HydrophobicContact CB-CE1 4.48Å; R278-F280 HydrophobicContact CB-CE2 3.75Å; R278-F280 HydrophobicContact CB-CZ 3.8Å; R278-F280 VanDerWaalsContact O-CD2 3.31Å; R278-F280 WeakPolarHBondContact O-CD2 3.42Å; R278-F280 WeakPolarHBondContact O-CE2 3.29Å; F280-F305 HydrophobicContact CB-CE1 4.4Å; F280-L338 HydrophobicContact CB-CB 3.83Å; F280-L338 HydrophobicContact CB-CD1 3.76Å; F280-L338 HydrophobicContact CB-CG 4.47Å; F280-L338 HydrophobicContact CD1-CD1 4.27Å; F280-L338 HydrophobicContact CG-CD1 4.28Å; F280-L338 CarbonylContact O-C 3.03Å; F280-L338 WeakPolarHBondContact O-CB 3.16Å; F280-G339 PolarHBondContact O-N 2.75Å; F280-G340 VanDerWaalsContact O-CA 3.23Å; F280-G340 WeakPolarHBondContact O-CA 3.42Å; F280-G340 PolarHBondContact O-N 2.76Å; F280-R341 PolarHBondContact N-O 3.48Å; F280-A343 HydrophobicContact CD2-CB 4.1Å; F280-A343 HydrophobicContact CE2-CB 3.92Å; F280-L346 HydrophobicContact CD1-CD1 3.91Å; F280-L346 HydrophobicContact CD2-CD2 4.22Å; F280-L346 HydrophobicContact CE1-CD1 3.92Å; F280-L346 HydrophobicContact CE2-CD2 4.38Å; F280-L346 HydrophobicContact CE2-CG 4.47Å; F280-L346 HydrophobicContact CG-CD1 4.22Å; F280-L346 HydrophobicContact CZ-CD1 4.24Å; F280-L346 HydrophobicContact CZ-CG 4.45Å; F280-F364 HydrophobicContact CD1-CB 4.33Å; F280-F364 HydrophobicContact CD1-CD1 4.25Å; F280-F364 HydrophobicContact CE1-CB 4.17Å; F280-F364 HydrophobicContact CE1-CD1 4.26Å; F280-F364 HydrophobicContact CE1-CG 4.43Å
281Q93.9Very high94.6Very high100 Ų10027.2 Ų27.247%0.46713%0.13SC..EExtended strand (participates in β ladder)trans-74.3-51.9176-54.5-172.914.400110.4A279 L338 G339 I365 D367A279-Q281 PolarHBondContact O-N 3.05Å; Q281-L338 PolarHBondContact O-N 2.86Å; Q281-G339 PolarHBondContact O-N 3.16Å; Q281-I365 HydrophobicContact CB-CG2 4.14Å; Q281-I365 WeakPolarHBondContact CB-O 3.23Å; Q281-I365 HydrophobicContact CG-CG2 4.48Å; Q281-I365 PolarHBondContact N-O 3.37Å; Q281-D367 PolarHBondContact NE2-OD2 3.03Å
282A93.2Very high94.3Very high12 Ų1229.4 Ų29.410%0.09915%0.147CC..EExtended strand (participates in β ladder)trans-154.6158.3179.800000112.4V336 I365A282-V336 CarbonylContact C-O 3.6Å; A282-V336 VanDerWaalsContact CA-O 3.24Å; A282-V336 WeakPolarHBondContact CA-O 3.46Å; A282-V336 WeakPolarHBondContact CB-O 3.44Å; A282-I365 PolarHBondContact N-O 2.83Å; A282-I365 PolarHBondContact O-N 3.04Å
283M94.9Very high94.1Very high0 Ų031.6 Ų31.60%016%0.158CC..EExtended strand (participates in β ladder)trans-109.6142.2162.6171.7-179.667.800108V285 V301 V336 L338 C348 F350 I362 F364M283-V285 HydrophobicContact CE-CG2 4.16Å; M283-V285 HydrophobicContact CG-CG2 4.12Å; M283-V285 HydrophobicContact SD-CG2 4.22Å; M283-V301 HydrophobicContact CE-CG1 3.81Å; M283-V336 HydrophobicContact CE-CB 4.25Å; M283-V336 HydrophobicContact CE-CG2 4.19Å; M283-V336 PolarHBondContact N-O 2.7Å; M283-V336 PolarHBondContact O-N 3.18Å; M283-L338 HydrophobicContact CB-CD1 3.83Å; M283-L338 HydrophobicContact CB-CG 4.28Å; M283-C348 HydrophobicContact CE-CB 4.43Å; M283-F350 HydrophobicContact CE-CE1 3.71Å; M283-F350 HydrophobicContact CE-CZ 3.8Å; M283-F350 HydrophobicContact SD-CZ 4.19Å; M283-I362 HydrophobicContact CG-CG2 4.08Å; M283-I362 HydrophobicContact SD-CG2 4.09Å; M283-F364 HydrophobicContact CB-CD1 3.85Å; M283-F364 HydrophobicContact CB-CE1 3.8Å; M283-F364 HydrophobicContact CG-CD1 3.96Å; M283-F364 HydrophobicContact CG-CE1 3.53Å; M283-F364 HydrophobicContact CG-CZ 4.01Å; M283-F364 HydrophobicContact SD-CD1 4.47Å; M283-F364 HydrophobicContact SD-CE1 3.49Å; M283-F364 WeakPolarHBondContact SD-CE1 3.36Å; M283-F364 HydrophobicContact SD-CZ 3.76Å
284Q94.6Very high93.9Very high12 Ų1229.5 Ų29.56%0.05615%0.152CC..EExtended strand (participates in β ladder)trans-125.8126.1176.2-160.7165.48.300109.9M22 K23 A333 V334 I362 S363M22-Q284 HydrophobicContact CE-CB 4.32Å; M22-Q284 HydrophobicContact CE-CG 4.38Å; M22-Q284 WeakPolarHBondContact CE-O 3.43Å; M22-Q284 HydrophobicContact CG-CB 4.4Å; M22-Q284 VanDerWaalsContact CG-CD 3.49Å; M22-Q284 HydrophobicContact CG-CG 3.83Å; M22-Q284 HydrophobicContact SD-CG 4.35Å; K23-Q284 VanDerWaalsContact N-OE1 3.17Å; Q284-A333 HydrophobicContact CG-CB 4.07Å; Q284-V334 CarbonylContact C-O 3.57Å; Q284-V334 VanDerWaalsContact CA-O 3.31Å; Q284-V334 WeakPolarHBondContact CA-O 3.4Å; Q284-I362 WeakPolarHBondContact O-CA 3.47Å; Q284-S363 PolarHBondContact N-O 3.3Å; Q284-S363 PolarHBondContact O-N 3.15Å
285V95.1Very high93.8Very high2 Ų229.5 Ų29.51%0.01215%0.152CC..EExtended strand (participates in β ladder)trans-119.5124.3-175.9-178.30000109M283 C287 A333 V334 F350 F359 E361 I362M283-V285 HydrophobicContact CE-CG2 4.16Å; M283-V285 HydrophobicContact CG-CG2 4.12Å; M283-V285 HydrophobicContact SD-CG2 4.22Å; V285-C287 VanDerWaalsContact CG1-SG 3.52Å; V285-C287 PolarHBondContact O-N 2.9Å; V285-A333 CarbonylContact O-C 3.56Å; V285-A333 WeakPolarHBondContact O-CA 3.21Å; V285-V334 PolarHBondContact N-O 2.51Å; V285-V334 PolarHBondContact O-N 3.26Å; V285-F350 HydrophobicContact CG2-CE1 3.98Å; V285-F350 HydrophobicContact CG2-CZ 4.43Å; V285-F359 HydrophobicContact CG1-CB 4.14Å; V285-F359 HydrophobicContact CG1-CD1 3.6Å; V285-F359 HydrophobicContact CG1-CD2 4.05Å; V285-F359 HydrophobicContact CG1-CE1 4Å; V285-F359 HydrophobicContact CG1-CE2 4.4Å; V285-F359 HydrophobicContact CG1-CG 3.67Å; V285-F359 HydrophobicContact CG1-CZ 4.38Å; V285-E361 WeakPolarHBondContact CA-O 3.28Å; V285-I362 HydrophobicContact CG1-CG1 4.12Å; V285-I362 HydrophobicContact CG2-CG1 4.23Å; V285-I362 HydrophobicContact CG2-CG2 4.21Å
286H95.9Very high93.9Very high14 Ų1429.9 Ų29.97%0.06515%0.15CC..EExtended strand (participates in β ladder)trans-81.2111.3171.2-169.5-100.5000110.6M22 G237 A331 F359 S360 E361M22-H286 HydrophobicContact SD-CB 4.19Å; G237-H286 PolarHBondContact O-CE1 3.18Å; G237-H286 VanDerWaalsContact O-CE1 3.27Å; H286-A331 VanDerWaalsContact CE1-CB 3.42Å; H286-A331 WeakPolarHBondContact CE1-CB 3.34Å; H286-F359 CarbonylContact O-C 3.52Å; H286-F359 VanDerWaalsContact O-CA 3.27Å; H286-F359 WeakPolarHBondContact O-CA 3.38Å; H286-S360 PolarHBondContact ND1-OG 2.9Å; H286-S360 PolarHBondContact O-N 3.02Å; H286-E361 HydrophobicContact CB-CB 4.26Å; H286-E361 PolarHBondContact N-O 2.83Å
287C95.1Very high94Very high0 Ų025.4 Ų25.40%014%0.135CC..EExtended strand (participates in β ladder)trans-113.9138.8-174.4-61.70000111.3V285 L297 A331 R332 V334 L358 F359V285-C287 VanDerWaalsContact CG1-SG 3.52Å; V285-C287 PolarHBondContact O-N 2.9Å; C287-L297 HydrophobicContact CB-CD2 3.44Å; C287-L297 VanDerWaalsContact CB-CD2 3.44Å; C287-A331 CarbonylContact O-C 3.21Å; C287-A331 VanDerWaalsContact O-CA 3.3Å; C287-A331 WeakPolarHBondContact O-CA 3.07Å; C287-A331 WeakPolarHBondContact O-CB 3.09Å; C287-R332 PolarHBondContact N-O 3.3Å; C287-R332 PolarHBondContact O-N 3.38Å; C287-V334 HydrophobicContact CB-CG2 4.15Å; C287-L358 WeakPolarHBondContact CA-O 3.27Å; C287-F359 HydrophobicContact CB-CD1 4.3Å; C287-F359 VanDerWaalsContact SG-CD1 3.53Å; C287-F359 VanDerWaalsContact SG-CE1 3.51Å
288N96.3Very high94Very high0 Ų023.7 Ų23.70%013%0.126CC..  trans-76.1147.4167-161.2-91.6000111.5L238 D239 F241 Y255 M290 A295 R296 L358L238-N288 PolarHBondContact O-ND2 3.01Å; D239-N288 PolarHBondContact O-ND2 2.99Å; F241-N288 WeakPolarHBondContact CD1-OD1 3.32Å; Y255-N288 HydrophobicContact CD1-CB 4.3Å; Y255-N288 HydrophobicContact CE1-CB 3.61Å; Y255-N288 PolarHBondContact OH-ND2 2.84Å; N288-M290 WeakPolarHBondContact OD1-CB 3.32Å; N288-M290 PolarHBondContact OD1-N 2.83Å; N288-A295 HydrophobicContact CB-CB 4.36Å; N288-R296 CarbonylContact O-C 3.53Å; N288-L358 HydrophobicContact CB-CB 3.94Å; N288-L358 HydrophobicContact CB-CD1 4.09Å; N288-L358 HydrophobicContact CB-CG 4.44Å; N288-L358 PolarHBondContact N-O 3.01Å
289N94.9Very high93.9Very high4 Ų424.5 Ų24.52%0.02114%0.139CC..  trans-128.122.9173.7-162.149.2000113.5H291 A295 R296 L297 L326 D328 P329 R330N289-H291 PolarHBondContact O-CD2 2.9Å; N289-H291 VanDerWaalsContact O-CD2 3.24Å; N289-H291 PolarHBondContact O-N 2.7Å; N289-A295 CarbonylContact C-O 3.19Å; N289-R296 WeakPolarHBondContact OD1-CA 3.34Å; N289-L297 HydrophobicContact CB-CD2 4Å; N289-L297 HydrophobicContact CB-CG 3.96Å; N289-L297 PolarHBondContact OD1-N 3.12Å; N289-L297 VanDerWaalsContact OD1-N 3.12Å; N289-L326 PolarHBondContact ND2-O 3.16Å; N289-D328 PolarHBondContact ND2-O 2.91Å; N289-P329 CarbonylContact C-O 3.49Å; N289-P329 WeakPolarHBondContact O-CA 3.48Å; N289-R330 WeakPolarHBondContact CB-O 3.44Å
290M94.1Very high93.9Very high28 Ų2823.6 Ų23.614%0.13813%0.131CC..  trans-71.473178.8-173.3168-76.300111.2D239 D240 F241 N288 T292 L293 G294 A295 P329D239-M290 WeakPolarHBondContact O-CE 3.39Å; D240-M290 HydrophobicContact CB-CE 3.93Å; F241-M290 HydrophobicContact CD1-CB 4.1Å; F241-M290 HydrophobicContact CD1-SD 4.43Å; F241-M290 HydrophobicContact CE1-CB 4.02Å; F241-M290 HydrophobicContact CE1-CG 4.31Å; F241-M290 HydrophobicContact CE1-SD 4.3Å; N288-M290 WeakPolarHBondContact OD1-CB 3.32Å; N288-M290 PolarHBondContact OD1-N 2.83Å; M290-T292 VanDerWaalsContact CG-OG1 3.26Å; M290-T292 WeakPolarHBondContact CG-OG1 3.43Å; M290-T292 PolarHBondContact O-N 3.46Å; M290-L293 HydrophobicContact CG-CB 4.49Å; M290-L293 HydrophobicContact CG-CD1 4.46Å; M290-L293 HydrophobicContact CG-CG 4.36Å; M290-L293 PolarHBondContact O-N 3.42Å; M290-L293 HydrophobicContact SD-CD1 3.82Å; M290-L293 HydrophobicContact SD-CG 4.3Å; M290-G294 PolarHBondContact O-N 3.2Å; M290-A295 CarbonylContact C-O 3.34Å; M290-A295 VanDerWaalsContact C-O 3.24Å; M290-A295 PolarHBondContact N-O 2.94Å; M290-A295 PolarHBondContact O-N 3.24Å; M290-P329 PolarHBondContact N-O 3.22Å
291H91.1Very high93.9Very high51 Ų5123.7 Ų23.724%0.23613%0.132CC..G310 helixtrans-69.3-16.8-172.660.182.8000113.6N289 L293 G294 A295 R296 G327N289-H291 PolarHBondContact O-CD2 2.9Å; N289-H291 VanDerWaalsContact O-CD2 3.24Å; N289-H291 PolarHBondContact O-N 2.7Å; H291-L293 PolarHBondContact O-N 2.85Å; H291-G294 PolarHBondContact O-N 2.69Å; H291-G294 VanDerWaalsContact O-N 3.1Å; H291-A295 WeakPolarHBondContact CA-O 3.29Å; H291-A295 PolarHBondContact N-O 2.71Å; H291-A295 VanDerWaalsContact N-O 3.07Å; H291-R296 HydrophobicContact CB-CG 3.8Å; H291-R296 PolarHBondContact ND1-NH2 2.79Å; H291-G327 PolarHBondContact NE2-O 2.7Å
292T91.4Very high94Very high103 Ų10320.6 Ų20.663%0.63212%0.117SC*.G310 helixtrans-60.1-2516749.80000113.2M290M290-T292 VanDerWaalsContact CG-OG1 3.26Å; M290-T292 WeakPolarHBondContact CG-OG1 3.43Å; M290-T292 PolarHBondContact O-N 3.46Å
293L92.7Very high94.1Very high47 Ų4720 Ų2025%0.24611%0.112CC..G310 helixtrans-114.917.8173.4-58.4179.9000112.2L204 F241 M290 H291 A295L204-L293 HydrophobicContact CD1-CB 4.44Å; L204-L293 HydrophobicContact CD1-CD1 4.1Å; L204-L293 HydrophobicContact CD1-CD2 4.28Å; F241-L293 HydrophobicContact CE1-CB 3.87Å; F241-L293 HydrophobicContact CE1-CD1 4.01Å; F241-L293 HydrophobicContact CZ-CB 3.74Å; F241-L293 HydrophobicContact CZ-CD1 3.9Å; F241-L293 HydrophobicContact CZ-CG 4.49Å; M290-L293 HydrophobicContact CG-CB 4.49Å; M290-L293 HydrophobicContact CG-CD1 4.46Å; M290-L293 HydrophobicContact CG-CG 4.36Å; M290-L293 PolarHBondContact O-N 3.42Å; M290-L293 HydrophobicContact SD-CD1 3.82Å; M290-L293 HydrophobicContact SD-CG 4.3Å; H291-L293 PolarHBondContact O-N 2.85Å; L293-A295 PolarHBondContact O-N 2.75Å
294G91.8Very high94.1Very high12 Ų1223.5 Ų23.512%0.12413%0.125CC..THydrogen-bonded Turntrans86.1-4.7173.600000116.7M290 H291 P355 W356M290-G294 PolarHBondContact O-N 3.2Å; H291-G294 PolarHBondContact O-N 2.69Å; H291-G294 VanDerWaalsContact O-N 3.1Å; G294-P355 WeakPolarHBondContact O-CD 3.46Å; G294-W356 PolarHBondContact O-N 3.09Å
295A94.7Very high94.1Very high0 Ų023 Ų230%012%0.123CC..BIsolated β-bridgetrans-77.3131.6173.400000111.2F241 N288 N289 M290 H291 L293 L358F241-A295 HydrophobicContact CD1-CB 4.47Å; F241-A295 HydrophobicContact CE1-CB 4.12Å; N288-A295 HydrophobicContact CB-CB 4.36Å; N289-A295 CarbonylContact C-O 3.19Å; M290-A295 CarbonylContact C-O 3.34Å; M290-A295 VanDerWaalsContact C-O 3.24Å; M290-A295 PolarHBondContact N-O 2.94Å; M290-A295 PolarHBondContact O-N 3.24Å; H291-A295 WeakPolarHBondContact CA-O 3.29Å; H291-A295 PolarHBondContact N-O 2.71Å; H291-A295 VanDerWaalsContact N-O 3.07Å; L293-A295 PolarHBondContact O-N 2.75Å; A295-L358 HydrophobicContact CB-CD1 3.65Å; A295-L358 HydrophobicContact CB-CG 3.91Å
296R93.9Very high93.9Very high50 Ų5024.8 Ų24.819%0.18913%0.13CC..  trans-138155.1174.6-76.7-172176.5-75.5-4.1111.6N288 N289 H291 N325 A353 W356N288-R296 CarbonylContact O-C 3.53Å; N289-R296 WeakPolarHBondContact OD1-CA 3.34Å; H291-R296 HydrophobicContact CB-CG 3.8Å; H291-R296 PolarHBondContact ND1-NH2 2.79Å; R296-N325 PolarHBondContact NH1-OD1 3.08Å; R296-A353 VanDerWaalsContact CD-O 3.28Å; R296-A353 WeakPolarHBondContact CD-O 3.44Å; R296-W356 PolarHBondContact N-O 3.04Å; R296-W356 VanDerWaalsContact N-O 3.16Å
297L93.4Very high93.6Very high28 Ų2828.9 Ų28.915%0.14715%0.145CC..  trans-54.4148.1163.8-55.6-178.2000110.4C287 N289 V334 A353C287-L297 HydrophobicContact CB-CD2 3.44Å; C287-L297 VanDerWaalsContact CB-CD2 3.44Å; N289-L297 HydrophobicContact CB-CD2 4Å; N289-L297 HydrophobicContact CB-CG 3.96Å; N289-L297 PolarHBondContact OD1-N 3.12Å; N289-L297 VanDerWaalsContact OD1-N 3.12Å; L297-V334 HydrophobicContact CD2-CG2 4.02Å; L297-A353 WeakPolarHBondContact O-CB 3.43Å
298P94.3Very high92.9Very high4 Ų429.5 Ų29.53%0.02615%0.151CC..  trans-61.3143.1173.922.8-30.3000111.7G300 V301 L322 F350 L351 L357 F359P298-G300 PolarHBondContact O-N 2.9Å; P298-V301 HydrophobicContact CG-CG2 4.44Å; P298-L322 HydrophobicContact CB-CD1 4.42Å; P298-L322 HydrophobicContact CG-CD1 3.87Å; P298-L322 WeakPolarHBondContact O-CB 3.4Å; P298-L322 WeakPolarHBondContact O-CD1 3.03Å; P298-F350 HydrophobicContact CB-CB 4.43Å; P298-L351 CarbonylContact C-O 3.53Å; P298-L351 VanDerWaalsContact CA-O 3.29Å; P298-L351 WeakPolarHBondContact CA-O 3.47Å; P298-L357 HydrophobicContact CB-CD2 3.78Å; P298-L357 HydrophobicContact CG-CD2 4.35Å; P298-F359 HydrophobicContact CG-CE1 4.42Å
299G91.4Very high91.7Very high29 Ų2934 Ų3430%0.29918%0.18SC..SBendtrans-72.7-16.9178.200000113.2L322 L351G299-L322 PolarHBondContact O-N 2.94Å; G299-L351 PolarHBondContact N-O 3.06Å
300G93.6Very high90.5Very high0 Ų038.9 Ų38.90%022%0.221CC..EExtended strand (participates in β ladder)trans176.4166.3173.300000111.1P298 H320 L351P298-G300 PolarHBondContact O-N 2.9Å; G300-H320 CarbonylContact C-O 3.58Å; G300-H320 WeakPolarHBondContact CA-O 3.45Å; G300-L351 WeakPolarHBondContact O-CB 3.32Å; G300-L351 PolarHBondContact O-N 3.26Å
301V95.9Very high89.8Confident1 Ų142.8 Ų42.81%0.00624%0.24CC..EExtended strand (participates in β ladder)trans-128.8129.9-179.6-172.60000109.4M283 P298 R319 H320 L322 V336 C348 R349 F350M283-V301 HydrophobicContact CE-CG1 3.81Å; P298-V301 HydrophobicContact CG-CG2 4.44Å; V301-R319 CarbonylContact O-C 3.38Å; V301-R319 WeakPolarHBondContact O-CA 3.24Å; V301-H320 PolarHBondContact N-O 2.9Å; V301-H320 PolarHBondContact O-N 2.86Å; V301-L322 HydrophobicContact CG2-CD1 4.22Å; V301-V336 HydrophobicContact CB-CG1 4.3Å; V301-V336 HydrophobicContact CB-CG2 4.06Å; V301-V336 HydrophobicContact CG1-CG1 4.4Å; V301-V336 HydrophobicContact CG1-CG2 4.4Å; V301-V336 HydrophobicContact CG2-CG2 3.87Å; V301-C348 HydrophobicContact CG1-CB 4.46Å; V301-R349 VanDerWaalsContact CA-O 3.28Å; V301-R349 WeakPolarHBondContact CA-O 3.44Å; V301-F350 HydrophobicContact CB-CD1 4.45Å; V301-F350 HydrophobicContact CG1-CD1 3.94Å; V301-F350 HydrophobicContact CG1-CE1 3.76Å; V301-F350 HydrophobicContact CG1-CZ 4.42Å; V301-F350 HydrophobicContact CG2-CD1 3.7Å; V301-F350 HydrophobicContact CG2-CE1 4.03Å
302E95.1Very high89.3Confident35 Ų3544.5 Ų44.516%0.16426%0.263CS..EExtended strand (participates in β ladder)trans-112.1118.8171.8179.9-166.213400108.9R304 P317 M318 C348 R349E302-R304 IonicContact OE1-CZ 3.23Å; E302-R304 VanDerWaalsContact OE1-CZ 3.23Å; E302-R304 IonicContact OE1-NE 2.86Å; E302-R304 PolarHBondContact OE1-NE 3.14Å; E302-R304 IonicContact OE1-NH2 2.74Å; E302-R304 PolarHBondContact OE1-NH2 3.38Å; E302-P317 HydrophobicContact CG-CB 3.52Å; E302-P317 HydrophobicContact CG-CG 3.8Å; E302-M318 CarbonylContact C-O 3.59Å; E302-M318 WeakPolarHBondContact CA-O 3.47Å; E302-C348 CarbonylContact O-C 3.56Å; E302-C348 VanDerWaalsContact O-CA 3.27Å; E302-C348 WeakPolarHBondContact O-CA 3.3Å; E302-R349 HydrophobicContact CB-CB 4.32Å; E302-R349 PolarHBondContact N-O 2.72Å; E302-R349 PolarHBondContact O-N 2.79Å; E302-R349 IonicContact OE1-NH1 3.78Å; E302-R349 PolarHBondContact OE1-NH1 3.25Å
303C95.6Very high89Confident0 Ų043.1 Ų43.10%025%0.247CC..EExtended strand (participates in β ladder)trans-117136.9177.2-68.10000112.8F305 P317 M318 L338 Q347 C348C303-F305 HydrophobicContact CB-CE2 4.23Å; C303-F305 HydrophobicContact CB-CZ 4.41Å; C303-F305 WeakPolarHBondContact O-CE2 3.31Å; C303-P317 CarbonylContact O-C 3.56Å; C303-P317 WeakPolarHBondContact O-CA 3.35Å; C303-P317 WeakPolarHBondContact O-CB 3.17Å; C303-M318 PolarHBondContact N-O 2.92Å; C303-M318 PolarHBondContact O-N 3.31Å; C303-L338 HydrophobicContact CB-CD2 3.96Å; C303-Q347 CarbonylContact C-O 3.43Å; C303-Q347 WeakPolarHBondContact CA-O 3.39Å; C303-C348 HydrophobicContact CB-CB 4.23Å; C303-C348 WeakPolarHBondContact CB-SG 3.4Å; C303-C348 WeakPolarHBondContact SG-CB 3.43Å; C303-C348 CovalentContact SG-SG 2.05Å; C303-C348 PolarHBondContact SG-SG 3.28Å
304R94.6Very high88.2Confident73 Ų7345.2 Ų45.228%0.27526%0.255SS..EExtended strand (participates in β ladder)trans-112.9149.2176.1-68166.7-176.3-98.9-9109.5E302 W313 P317 L346 Q347E302-R304 IonicContact OE1-CZ 3.23Å; E302-R304 VanDerWaalsContact OE1-CZ 3.23Å; E302-R304 IonicContact OE1-NE 2.86Å; E302-R304 PolarHBondContact OE1-NE 3.14Å; E302-R304 IonicContact OE1-NH2 2.74Å; E302-R304 PolarHBondContact OE1-NH2 3.38Å; R304-W313 HydrophobicContact CB-CD2 4.14Å; R304-W313 HydrophobicContact CB-CE3 3.74Å; R304-W313 HydrophobicContact CB-CZ3 4.31Å; R304-P317 HydrophobicContact CG-CB 3.83Å; R304-L346 VanDerWaalsContact O-CA 3.32Å; R304-L346 WeakPolarHBondContact O-CA 3.35Å; R304-Q347 HydrophobicContact CB-CB 4.34Å; R304-Q347 PolarHBondContact N-O 2.61Å; R304-Q347 PolarHBondContact O-N 3.31Å
305F94.1Very high87.3Confident1 Ų147.6 Ų47.60%0.00428%0.279CS..EExtended strand (participates in β ladder)trans-124137.1-167.9-63.1-100.6000109.9F280 C303 W313 E314 M318 L338 R341 A343 L346F280-F305 HydrophobicContact CB-CE1 4.4Å; C303-F305 HydrophobicContact CB-CE2 4.23Å; C303-F305 HydrophobicContact CB-CZ 4.41Å; C303-F305 WeakPolarHBondContact O-CE2 3.31Å; F305-W313 CarbonylContact O-C 3.45Å; F305-W313 WeakPolarHBondContact O-CA 3.37Å; F305-E314 HydrophobicContact CB-CB 4.44Å; F305-E314 WeakPolarHBondContact O-CB 3.36Å; F305-E314 PolarHBondContact O-N 3.46Å; F305-M318 HydrophobicContact CE2-CB 3.89Å; F305-M318 HydrophobicContact CE2-CG 3.48Å; F305-M318 VanDerWaalsContact CE2-CG 3.48Å; F305-M318 HydrophobicContact CZ-CB 4.28Å; F305-M318 HydrophobicContact CZ-CG 3.78Å; F305-L338 HydrophobicContact CE1-CB 4.11Å; F305-L338 HydrophobicContact CZ-CB 3.97Å; F305-L338 HydrophobicContact CZ-CD2 3.89Å; F305-L338 HydrophobicContact CZ-CG 4.37Å; F305-R341 HydrophobicContact CD1-CB 3.61Å; F305-R341 HydrophobicContact CD1-CG 4.49Å; F305-R341 HydrophobicContact CE1-CB 3.68Å; F305-R341 HydrophobicContact CE1-CG 4.39Å; F305-R341 HydrophobicContact CG-CB 4.12Å; F305-R341 HydrophobicContact CZ-CB 4.24Å; F305-R341 HydrophobicContact CZ-CG 4.48Å; F305-A343 HydrophobicContact CB-CB 4.08Å; F305-A343 HydrophobicContact CD1-CB 4.04Å; F305-L346 HydrophobicContact CD1-CD2 3.28Å; F305-L346 HydrophobicContact CE1-CD2 3.52Å; F305-L346 HydrophobicContact CG-CD2 3.98Å; F305-L346 HydrophobicContact CZ-CD2 4.36Å
306R92.4Very high86.6Confident41 Ų4155.1 Ų55.116%0.15532%0.315CS..EExtended strand (participates in β ladder)trans-143.8131.9178166.8171.359.3153.5-5.6110.6E271 G308 P309 M311 W313 R344 F345E271-R306 IonicContact OE2-NH2 3.05Å; E271-R306 PolarHBondContact OE2-NH2 3.32Å; R306-G308 WeakPolarHBondContact CD-O 3.47Å; R306-G308 WeakPolarHBondContact CG-O 3.12Å; R306-P309 PolarHBondContact NH1-O 3.13Å; R306-P309 VanDerWaalsContact NH1-O 3.14Å; R306-M311 WeakPolarHBondContact CD-O 3.5Å; R306-W313 HydrophobicContact CB-CD2 4.05Å; R306-W313 HydrophobicContact CB-CE3 3.41Å; R306-W313 VanDerWaalsContact CB-CE3 3.41Å; R306-W313 HydrophobicContact CB-CH2 4.23Å; R306-W313 HydrophobicContact CB-CZ3 3.51Å; R306-W313 VanDerWaalsContact NH2-CZ2 3.33Å; R306-R344 PolarHBondContact O-N 2.92Å; R306-F345 HydrophobicContact CB-CB 4.11Å; R306-F345 HydrophobicContact CG-CB 4.39Å; R306-F345 HydrophobicContact CG-CD2 4.42Å; R306-F345 PolarHBondContact N-O 3.27Å; R306-F345 PolarHBondContact O-N 2.96Å
307R89.6Confident86.1Confident100 Ų10054 Ų5438%0.37731%0.314SS..SBendtrans-87.3-21.6-172.7-71.4177.769.1179.93.7114.6L277 M311 E314 V342L277-R307 HydrophobicContact CD2-CB 3.92Å; L277-R307 HydrophobicContact CD2-CG 4Å; R307-M311 HydrophobicContact CB-SD 3.9Å; R307-E314 WeakPolarHBondContact CD-OE2 3.16Å; R307-E314 VanDerWaalsContact CG-OE2 3.29Å; R307-E314 WeakPolarHBondContact CG-OE2 3.23Å; R307-V342 WeakPolarHBondContact CD-O 3.38Å; R307-V342 WeakPolarHBondContact CG-O 3.47Å
308G79.1Confident85.8Confident12 Ų1255 Ų5512%0.12432%0.319CS..SBendtrans-160.5158.117500000110.8R306 A310 M311R306-G308 WeakPolarHBondContact CD-O 3.47Å; R306-G308 WeakPolarHBondContact CG-O 3.12Å; G308-A310 VanDerWaalsContact C-N 3.29Å; G308-A310 PolarHBondContact O-N 2.93Å; G308-M311 WeakPolarHBondContact O-CB 3.5Å; G308-M311 PolarHBondContact O-N 3.23Å
309P71.4Confident85.6Confident95 Ų9562.1 Ų62.162%0.61735%0.345SS*.THydrogen-bonded Turntrans-62.6-34.1-16723.8-34.2000113.6R306 F345R306-P309 PolarHBondContact NH1-O 3.13Å; R306-P309 VanDerWaalsContact NH1-O 3.14Å; P309-F345 HydrophobicContact CB-CE2 4.49Å; P309-F345 HydrophobicContact CB-CZ 4.32Å
310A69.8Low85.5Confident107 Ų10763.8 Ų63.888%0.88435%0.345SS*.THydrogen-bonded Turntrans-88.87.4178.500000114.5G308G308-A310 VanDerWaalsContact C-N 3.29Å; G308-A310 PolarHBondContact O-N 2.93Å
311M78.9Confident85.3Confident110 Ų11068.4 Ų68.454%0.54237%0.37SS..SBendtrans-95.9150.5175.3-58.4-172.775.900110.7R306 R307 G308R306-M311 WeakPolarHBondContact CD-O 3.5Å; R307-M311 HydrophobicContact CB-SD 3.9Å; G308-M311 WeakPolarHBondContact O-CB 3.5Å; G308-M311 PolarHBondContact O-N 3.23Å
312A81.6Confident84.5Confident87 Ų8770.3 Ų70.372%0.71938%0.379SS*.PPolyproline II helixtrans-62.8159.6168.800000111.5
313W84.9Confident82.9Confident74 Ų7471.8 Ų71.828%0.2840%0.404SS..PPolyproline II helixtrans-65.1138168.8-64.4105.4000110.4R304 F305 R306 G315 F345 Q347R304-W313 HydrophobicContact CB-CD2 4.14Å; R304-W313 HydrophobicContact CB-CE3 3.74Å; R304-W313 HydrophobicContact CB-CZ3 4.31Å; F305-W313 CarbonylContact O-C 3.45Å; F305-W313 WeakPolarHBondContact O-CA 3.37Å; R306-W313 HydrophobicContact CB-CD2 4.05Å; R306-W313 HydrophobicContact CB-CE3 3.41Å; R306-W313 VanDerWaalsContact CB-CE3 3.41Å; R306-W313 HydrophobicContact CB-CH2 4.23Å; R306-W313 HydrophobicContact CB-CZ3 3.51Å; R306-W313 VanDerWaalsContact NH2-CZ2 3.33Å; W313-G315 PolarHBondContact O-N 2.81Å; W313-F345 HydrophobicContact CH2-CB 4.43Å; W313-F345 HydrophobicContact CZ3-CB 4.49Å; W313-Q347 HydrophobicContact CH2-CB 3.39Å; W313-Q347 HydrophobicContact CZ2-CB 3.75Å; W313-Q347 HydrophobicContact CZ3-CB 3.82Å
314E76.9Confident81.1Confident90 Ų9075.2 Ų75.242%0.42144%0.44SS..  trans-90.996.7-164-170.5164.9179.200112.5F305 R307 R341F305-E314 HydrophobicContact CB-CB 4.44Å; F305-E314 WeakPolarHBondContact O-CB 3.36Å; F305-E314 PolarHBondContact O-N 3.46Å; R307-E314 WeakPolarHBondContact CD-OE2 3.16Å; R307-E314 VanDerWaalsContact CG-OE2 3.29Å; R307-E314 WeakPolarHBondContact CG-OE2 3.23Å; E314-R341 PolarHBondContact O-NH1 3.11Å
315G71.5Confident79.6Confident62 Ų6277.2 Ų77.264%0.63946%0.456SS*.SBendtrans71.6-165172.100000114.7W313W313-G315 PolarHBondContact O-N 2.81Å
316E79.4Confident78.3Confident159 Ų15979.6 Ų79.674%0.74347%0.468SS*.SBendtrans-65.7139.6173.8-70.6-58.4142.100111R341E316-R341 VanDerWaalsContact O-CZ 3.31Å; E316-R341 PolarHBondContact O-NH1 3.23Å; E316-R341 PolarHBondContact O-NH2 3.02Å
317P84.6Confident77.3Confident27 Ų2780.6 Ų80.618%0.17549%0.491CS..  trans-67.5151.9-17629.6-36.1000112.6E302 C303 R304 R319E302-P317 HydrophobicContact CG-CB 3.52Å; E302-P317 HydrophobicContact CG-CG 3.8Å; C303-P317 CarbonylContact O-C 3.56Å; C303-P317 WeakPolarHBondContact O-CA 3.35Å; C303-P317 WeakPolarHBondContact O-CB 3.17Å; R304-P317 HydrophobicContact CG-CB 3.83Å; P317-R319 PolarHBondContact O-N 3.02Å
318M86.9Confident77Confident49 Ų4979.6 Ų79.624%0.24149%0.493CS..EExtended strand (participates in β ladder)trans-75.1104.5167.3-71.4-66.4-72.400108.7E302 C303 F305 P337 R341E302-M318 CarbonylContact C-O 3.59Å; E302-M318 WeakPolarHBondContact CA-O 3.47Å; C303-M318 PolarHBondContact N-O 2.92Å; C303-M318 PolarHBondContact O-N 3.31Å; F305-M318 HydrophobicContact CE2-CB 3.89Å; F305-M318 HydrophobicContact CE2-CG 3.48Å; F305-M318 VanDerWaalsContact CE2-CG 3.48Å; F305-M318 HydrophobicContact CZ-CB 4.28Å; F305-M318 HydrophobicContact CZ-CG 3.78Å; M318-P337 VanDerWaalsContact CE-O 3.25Å; M318-P337 WeakPolarHBondContact CE-O 3.24Å; M318-R341 PolarHBondContact SD-NH2 3.21Å
319R89.5Confident77.5Confident152 Ų15281.4 Ų81.457%0.57450%0.503SS*.EExtended strand (participates in β ladder)trans-100.2120.6171-177.2172.9173156.11.4111V301 P317 N321V301-R319 CarbonylContact O-C 3.38Å; V301-R319 WeakPolarHBondContact O-CA 3.24Å; P317-R319 PolarHBondContact O-N 3.02Å; R319-N321 PolarHBondContact NE-OD1 3.21Å; R319-N321 PolarHBondContact NH2-OD1 2.77Å; R319-N321 VanDerWaalsContact NH2-OD1 3.07Å
320H90.3Very high78.3Confident64 Ų6483.8 Ų83.830%0.29650%0.5SS..EExtended strand (participates in β ladder)trans-115.9110.8172.9-172.977000109.1G300 V301 V336G300-H320 CarbonylContact C-O 3.58Å; G300-H320 WeakPolarHBondContact CA-O 3.45Å; V301-H320 PolarHBondContact N-O 2.9Å; V301-H320 PolarHBondContact O-N 2.86Å; H320-V336 HydrophobicContact CB-CG1 4.05Å
321N88.1Confident79.4Confident98 Ų9879.5 Ų79.552%0.52446%0.464SS..EExtended strand (participates in β ladder)trans-83.2135.8173.1-59.8-46.5000109R319R319-N321 PolarHBondContact NE-OD1 3.21Å; R319-N321 PolarHBondContact NH2-OD1 2.77Å; R319-N321 VanDerWaalsContact NH2-OD1 3.07Å
322L80.6Confident79.9Confident40 Ų4078 Ų7821%0.20945%0.452CS..PPolyproline II helixtrans-96.9142.4-177.9-69.7159.5000109.8P298 G299 V301 G324 V334P298-L322 HydrophobicContact CB-CD1 4.42Å; P298-L322 HydrophobicContact CG-CD1 3.87Å; P298-L322 WeakPolarHBondContact O-CB 3.4Å; P298-L322 WeakPolarHBondContact O-CD1 3.03Å; G299-L322 PolarHBondContact O-N 2.94Å; V301-L322 HydrophobicContact CG2-CD1 4.22Å; L322-G324 PolarHBondContact O-N 2.86Å; L322-V334 HydrophobicContact CD1-CG1 3.54Å; L322-V334 HydrophobicContact CD2-CG1 3.71Å; L322-V334 HydrophobicContact CG-CG1 4.29Å
323G60.4Low80.3Confident67 Ų6775.4 Ų75.469%0.69143%0.431SS*.PPolyproline II helixtrans-57.5135.7-174.900000112.4
324G59.1Low80.5Confident72 Ų7272.5 Ų72.574%0.74242%0.421SS*.SBendtrans-61.3142.3-167.700000115L322 L326L322-G324 PolarHBondContact O-N 2.86Å; G324-L326 PolarHBondContact O-N 2.85Å
325N61.8Low81.2Confident115 Ų11571 Ų7162%0.61542%0.421SS*.  trans23.676.2166.5-72.8-21.4000116.5R296 G327R296-N325 PolarHBondContact NH1-OD1 3.08Å; N325-G327 PolarHBondContact O-N 2.73Å
326L66.3Low82.2Confident51 Ų5168.1 Ų68.127%0.26739%0.391SS..  trans-57.4133.5162.5-91.366.2000110.1N289 G324N289-L326 PolarHBondContact ND2-O 3.16Å; G324-L326 PolarHBondContact O-N 2.85Å
327G71.7Confident82.8Confident61 Ų6163.4 Ų63.463%0.62937%0.374SS*.SBendtrans-80.4-23.4177.100000114.1H291 N325 P329H291-G327 PolarHBondContact NE2-O 2.7Å; N325-G327 PolarHBondContact O-N 2.73Å; G327-P329 WeakPolarHBondContact O-CD 3.39Å
328D84.1Confident83.2Confident79 Ų7962.1 Ų62.142%0.42237%0.365SS..  trans-68.9121175.4-174.7-6.1000110.3N289 R330N289-D328 PolarHBondContact ND2-O 2.91Å; D328-R330 PolarHBondContact O-N 2.86Å; D328-R330 WeakPolarHBondContact OD1-CB 3.29Å; D328-R330 VanDerWaalsContact OD1-CG 3.24Å; D328-R330 WeakPolarHBondContact OD1-CG 3.41Å; D328-R330 PolarHBondContact OD1-N 2.94Å; D328-R330 VanDerWaalsContact OD1-N 3.08Å
329P88.7Confident83.3Confident50 Ų5062.7 Ų62.733%0.32538%0.383SS..  trans-75.5-4.9-178.532.1-37.1000114.8N289 M290 G327N289-P329 CarbonylContact C-O 3.49Å; N289-P329 WeakPolarHBondContact O-CA 3.48Å; M290-P329 PolarHBondContact N-O 3.22Å; G327-P329 WeakPolarHBondContact O-CD 3.39Å
330R89.9Confident83.4Confident146 Ų14657.2 Ų57.255%0.55137%0.374SS*.  trans-58.8144.8-178.6-73.1174.8175.9-159.2-2.9113.5D239 N289 D328D239-R330 WeakPolarHBondContact OD1-CA 3.2Å; D239-R330 WeakPolarHBondContact OD1-CB 3.44Å; N289-R330 WeakPolarHBondContact CB-O 3.44Å; D328-R330 PolarHBondContact O-N 2.86Å; D328-R330 WeakPolarHBondContact OD1-CB 3.29Å; D328-R330 VanDerWaalsContact OD1-CG 3.24Å; D328-R330 WeakPolarHBondContact OD1-CG 3.41Å; D328-R330 PolarHBondContact OD1-N 2.94Å; D328-R330 VanDerWaalsContact OD1-N 3.08Å
331A91.3Very high83.3Confident16 Ų1657.7 Ų57.713%0.13237%0.373CS..  trans-68.8147.7170.800000110.5D239 Y255 H286 C287D239-A331 PolarHBondContact OD1-N 2.98Å; Y255-A331 WeakPolarHBondContact OH-CB 3.23Å; H286-A331 VanDerWaalsContact CE1-CB 3.42Å; H286-A331 WeakPolarHBondContact CE1-CB 3.34Å; C287-A331 CarbonylContact O-C 3.21Å; C287-A331 VanDerWaalsContact O-CA 3.3Å; C287-A331 WeakPolarHBondContact O-CA 3.07Å; C287-A331 WeakPolarHBondContact O-CB 3.09Å
332R89.4Confident83.5Confident80 Ų8055 Ų5530%0.30236%0.36SS..EExtended strand (participates in β ladder)trans-146.3144.5-176.9-60.7-168.879-165.64.2112.3V15 C287 V334V15-R332 PolarHBondContact O-NH2 2.77Å; C287-R332 PolarHBondContact N-O 3.3Å; C287-R332 PolarHBondContact O-N 3.38Å; R332-V334 PolarHBondContact O-N 2.66Å
333A89.9Confident84.1Confident32 Ų3253 Ų5326%0.26435%0.35SS..EExtended strand (participates in β ladder)trans-77.4100.8170.300000111.3M22 Q284 V285M22-A333 HydrophobicContact CB-CB 4.33Å; M22-A333 HydrophobicContact CG-CB 4.02Å; M22-A333 HydrophobicContact SD-CB 3.81Å; Q284-A333 HydrophobicContact CG-CB 4.07Å; V285-A333 CarbonylContact O-C 3.56Å; V285-A333 WeakPolarHBondContact O-CA 3.21Å
334V90.6Very high85.7Confident12 Ų1253.8 Ų53.87%0.07333%0.332CS..EExtended strand (participates in β ladder)trans-75.9118.1177.3174.20000109.9Q284 V285 C287 L297 L322 R332 V336Q284-V334 CarbonylContact C-O 3.57Å; Q284-V334 VanDerWaalsContact CA-O 3.31Å; Q284-V334 WeakPolarHBondContact CA-O 3.4Å; V285-V334 PolarHBondContact N-O 2.51Å; V285-V334 PolarHBondContact O-N 3.26Å; C287-V334 HydrophobicContact CB-CG2 4.15Å; L297-V334 HydrophobicContact CD2-CG2 4.02Å; L322-V334 HydrophobicContact CD1-CG1 3.54Å; L322-V334 HydrophobicContact CD2-CG1 3.71Å; L322-V334 HydrophobicContact CG-CG1 4.29Å; R332-V334 PolarHBondContact O-N 2.66Å; V334-V336 HydrophobicContact CG1-CG2 4.26Å
335S91.1Very high87.5Confident60 Ų6051.2 Ų51.242%0.4230%0.301SS..EExtended strand (participates in β ladder)trans-99.4124176.8-169.90000111.4
336V92.4Very high89.1Confident1 Ų145.8 Ų45.81%0.00627%0.271CS..EExtended strand (participates in β ladder)trans-111.9112.9-178.8179.40000108.8A282 M283 V301 H320 V334 L338A282-V336 CarbonylContact C-O 3.6Å; A282-V336 VanDerWaalsContact CA-O 3.24Å; A282-V336 WeakPolarHBondContact CA-O 3.46Å; A282-V336 WeakPolarHBondContact CB-O 3.44Å; M283-V336 HydrophobicContact CE-CB 4.25Å; M283-V336 HydrophobicContact CE-CG2 4.19Å; M283-V336 PolarHBondContact N-O 2.7Å; M283-V336 PolarHBondContact O-N 3.18Å; V301-V336 HydrophobicContact CB-CG1 4.3Å; V301-V336 HydrophobicContact CB-CG2 4.06Å; V301-V336 HydrophobicContact CG1-CG1 4.4Å; V301-V336 HydrophobicContact CG1-CG2 4.4Å; V301-V336 HydrophobicContact CG2-CG2 3.87Å; H320-V336 HydrophobicContact CB-CG1 4.05Å; V334-V336 HydrophobicContact CG1-CG2 4.26Å; V336-L338 HydrophobicContact CG1-CD2 4.17Å; V336-L338 PolarHBondContact O-N 2.88Å
337P93.1Very high90.5Very high60 Ų6044.2 Ų44.239%0.3926%0.263SS..EExtended strand (participates in β ladder)trans-70.2124178.227.9-33.2000110.8M318M318-P337 VanDerWaalsContact CE-O 3.25Å; M318-P337 WeakPolarHBondContact CE-O 3.24Å
338L92.8Very high91.7Very high0 Ų041.3 Ų41.30%023%0.233CC..EExtended strand (participates in β ladder)trans-99.9-6.5179.5-62.6-176.2000113F280 Q281 M283 C303 F305 V336 L346 F364F280-L338 HydrophobicContact CB-CB 3.83Å; F280-L338 HydrophobicContact CB-CD1 3.76Å; F280-L338 HydrophobicContact CB-CG 4.47Å; F280-L338 HydrophobicContact CD1-CD1 4.27Å; F280-L338 HydrophobicContact CG-CD1 4.28Å; F280-L338 CarbonylContact O-C 3.03Å; F280-L338 WeakPolarHBondContact O-CB 3.16Å; Q281-L338 PolarHBondContact O-N 2.86Å; M283-L338 HydrophobicContact CB-CD1 3.83Å; M283-L338 HydrophobicContact CB-CG 4.28Å; C303-L338 HydrophobicContact CB-CD2 3.96Å; F305-L338 HydrophobicContact CE1-CB 4.11Å; F305-L338 HydrophobicContact CZ-CB 3.97Å; F305-L338 HydrophobicContact CZ-CD2 3.89Å; F305-L338 HydrophobicContact CZ-CG 4.37Å; V336-L338 HydrophobicContact CG1-CD2 4.17Å; V336-L338 PolarHBondContact O-N 2.88Å; L338-L346 HydrophobicContact CD1-CD1 3.98Å; L338-F364 HydrophobicContact CD1-CD1 4.44Å
339G88.9Confident92.4Very high60 Ų6039.9 Ų39.962%0.61922%0.222SC*.EExtended strand (participates in β ladder)trans78.819.116200000115.7F280 Q281 R341F280-G339 PolarHBondContact O-N 2.75Å; Q281-G339 PolarHBondContact O-N 3.16Å; G339-R341 PolarHBondContact O-N 2.78Å
340G90.1Very high92.8Very high37 Ų3737.5 Ų37.538%0.38121%0.206SC..EExtended strand (participates in β ladder)trans74.39.1-179.300000114.3F280 V342F280-G340 VanDerWaalsContact O-CA 3.23Å; F280-G340 WeakPolarHBondContact O-CA 3.42Å; F280-G340 PolarHBondContact O-N 2.76Å; G340-V342 PolarHBondContact O-N 3.04Å
341R89.9Confident93.1Very high74 Ų7432.8 Ų32.828%0.27919%0.192SC..EExtended strand (participates in β ladder)trans-61135.8-177.9-68.6-171.6-173-157.413.6110.8F280 F305 E314 E316 M318 G339F280-R341 PolarHBondContact N-O 3.48Å; F305-R341 HydrophobicContact CD1-CB 3.61Å; F305-R341 HydrophobicContact CD1-CG 4.49Å; F305-R341 HydrophobicContact CE1-CB 3.68Å; F305-R341 HydrophobicContact CE1-CG 4.39Å; F305-R341 HydrophobicContact CG-CB 4.12Å; F305-R341 HydrophobicContact CZ-CB 4.24Å; F305-R341 HydrophobicContact CZ-CG 4.48Å; E314-R341 PolarHBondContact O-NH1 3.11Å; E316-R341 VanDerWaalsContact O-CZ 3.31Å; E316-R341 PolarHBondContact O-NH1 3.23Å; E316-R341 PolarHBondContact O-NH2 3.02Å; M318-R341 PolarHBondContact SD-NH2 3.21Å; G339-R341 PolarHBondContact O-N 2.78Å
342V92.3Very high93.3Very high41 Ų4133.2 Ų33.225%0.24819%0.191CC..EExtended strand (participates in β ladder)trans-89.8116.5-176.5179.30000110.5L277 R278 A279 R307 G340 V369L277-V342 HydrophobicContact CB-CG1 4.5Å; L277-V342 HydrophobicContact CD2-CG1 4.15Å; R278-V342 CarbonylContact O-C 3.52Å; R278-V342 VanDerWaalsContact O-CA 3.29Å; R278-V342 WeakPolarHBondContact O-CA 3.37Å; A279-V342 HydrophobicContact CB-CG2 4.15Å; R307-V342 WeakPolarHBondContact CD-O 3.38Å; R307-V342 WeakPolarHBondContact CG-O 3.47Å; G340-V342 PolarHBondContact O-N 3.04Å; V342-V369 HydrophobicContact CG1-CB 4.39Å; V342-V369 HydrophobicContact CG1-CG2 3.95Å; V342-V369 HydrophobicContact CG2-CG2 4.08Å
343A93.1Very high93.4Very high0 Ų031.4 Ų31.40%019%0.193CC..EExtended strand (participates in β ladder)trans-143.4172.9-179.200000112.3L277 R278 F280 F305 L346L277-A343 CarbonylContact C-O 3.26Å; L277-A343 WeakPolarHBondContact CA-O 3.41Å; R278-A343 PolarHBondContact N-O 2.73Å; R278-A343 PolarHBondContact O-N 2.63Å; F280-A343 HydrophobicContact CD2-CB 4.1Å; F280-A343 HydrophobicContact CE2-CB 3.92Å; F305-A343 HydrophobicContact CB-CB 4.08Å; F305-A343 HydrophobicContact CD1-CB 4.04Å; A343-L346 HydrophobicContact CB-CD2 4.11Å
344R94.1Very high93.4Very high83 Ų8330.5 Ų30.531%0.31319%0.187SC..EExtended strand (participates in β ladder)trans-123.6-18.7162.1178.6171.6165.7-165.9-10.2112.1E273 F274 L277 R306E273-R344 IonicContact OE1-CZ 2.75Å; E273-R344 IonicContact OE1-NE 3.38Å; E273-R344 IonicContact OE1-NH2 2.69Å; E273-R344 PolarHBondContact OE1-NH2 3.31Å; F274-R344 WeakPolarHBondContact CD2-O 3.12Å; F274-R344 PolarHBondContact N-O 3.18Å; F274-R344 VanDerWaalsContact O-CG 3.28Å; F274-R344 WeakPolarHBondContact O-CG 3.44Å; F274-R344 PolarHBondContact O-NE 3.17Å; L277-R344 HydrophobicContact CD2-CB 4.38Å; R306-R344 PolarHBondContact O-N 2.92Å
345F95.3Very high93.7Very high18 Ų1832.9 Ų32.98%0.07920%0.202CC..EExtended strand (participates in β ladder)trans-125134.3176.2-59.2-96.1000109.1F272 E273 R306 P309 W313F272-F345 VanDerWaalsContact O-CA 3.31Å; F272-F345 WeakPolarHBondContact O-CA 3.35Å; E273-F345 HydrophobicContact CB-CD1 3.95Å; E273-F345 HydrophobicContact CB-CE1 3.85Å; E273-F345 HydrophobicContact CG-CD1 4.02Å; E273-F345 HydrophobicContact CG-CE1 3.51Å; E273-F345 HydrophobicContact CG-CZ 3.99Å; E273-F345 WeakPolarHBondContact OE2-CE1 3.5Å; R306-F345 HydrophobicContact CB-CB 4.11Å; R306-F345 HydrophobicContact CG-CB 4.39Å; R306-F345 HydrophobicContact CG-CD2 4.42Å; R306-F345 PolarHBondContact N-O 3.27Å; R306-F345 PolarHBondContact O-N 2.96Å; P309-F345 HydrophobicContact CB-CE2 4.49Å; P309-F345 HydrophobicContact CB-CZ 4.32Å; W313-F345 HydrophobicContact CH2-CB 4.43Å; W313-F345 HydrophobicContact CZ3-CB 4.49Å
346L95.9Very high94Very high0 Ų031.6 Ų31.60%019%0.188CC..EExtended strand (participates in β ladder)trans-115.4144168.4-58177.1000109.3E271 F272 F274 F280 R304 F305 L338 A343 F364E271-L346 CarbonylContact C-O 3.55Å; E271-L346 VanDerWaalsContact CA-O 3.28Å; E271-L346 WeakPolarHBondContact CA-O 3.41Å; F272-L346 HydrophobicContact CB-CB 4.32Å; F272-L346 HydrophobicContact CD2-CB 4.42Å; F272-L346 PolarHBondContact N-O 3.44Å; F272-L346 PolarHBondContact O-N 3.41Å; F274-L346 HydrophobicContact CE2-CB 4.5Å; F274-L346 HydrophobicContact CE2-CD1 3.87Å; F274-L346 HydrophobicContact CE2-CG 3.96Å; F274-L346 HydrophobicContact CZ-CD1 4.14Å; F280-L346 HydrophobicContact CD1-CD1 3.91Å; F280-L346 HydrophobicContact CD2-CD2 4.22Å; F280-L346 HydrophobicContact CE1-CD1 3.92Å; F280-L346 HydrophobicContact CE2-CD2 4.38Å; F280-L346 HydrophobicContact CE2-CG 4.47Å; F280-L346 HydrophobicContact CG-CD1 4.22Å; F280-L346 HydrophobicContact CZ-CD1 4.24Å; F280-L346 HydrophobicContact CZ-CG 4.45Å; R304-L346 VanDerWaalsContact O-CA 3.32Å; R304-L346 WeakPolarHBondContact O-CA 3.35Å; F305-L346 HydrophobicContact CD1-CD2 3.28Å; F305-L346 HydrophobicContact CE1-CD2 3.52Å; F305-L346 HydrophobicContact CG-CD2 3.98Å; F305-L346 HydrophobicContact CZ-CD2 4.36Å; L338-L346 HydrophobicContact CD1-CD1 3.98Å; A343-L346 HydrophobicContact CB-CD2 4.11Å; L346-F364 HydrophobicContact CD1-CD1 3.84Å; L346-F364 HydrophobicContact CD1-CE1 3.59Å
347Q96.5Very high94.2Very high19 Ų1931.6 Ų31.69%0.08919%0.188CC..EExtended strand (participates in β ladder)trans-122.3117164.8173.6-172.59300107.1E269 M270 E271 C303 R304 W313E269-Q347 HydrophobicContact CG-CG 4.04Å; M270-Q347 CarbonylContact O-C 3.54Å; M270-Q347 WeakPolarHBondContact O-CA 3.44Å; E271-Q347 HydrophobicContact CG-CB 3.97Å; E271-Q347 HydrophobicContact CG-CG 4.03Å; E271-Q347 PolarHBondContact OE1-NE2 2.91Å; C303-Q347 CarbonylContact C-O 3.43Å; C303-Q347 WeakPolarHBondContact CA-O 3.39Å; R304-Q347 HydrophobicContact CB-CB 4.34Å; R304-Q347 PolarHBondContact N-O 2.61Å; R304-Q347 PolarHBondContact O-N 3.31Å; W313-Q347 HydrophobicContact CH2-CB 3.39Å; W313-Q347 HydrophobicContact CZ2-CB 3.75Å; W313-Q347 HydrophobicContact CZ3-CB 3.82Å
348C97.1Very high94.4Very high0 Ų028.8 Ų28.80%017%0.17CC..EExtended strand (participates in β ladder)trans-120.2141.3-177.2-66.30000111.6E269 M270 F272 M283 V301 E302 C303 F350E269-C348 WeakPolarHBondContact CA-O 3.26Å; M270-C348 PolarHBondContact N-O 2.97Å; M270-C348 PolarHBondContact O-N 3.32Å; F272-C348 HydrophobicContact CE2-CB 4.24Å; M283-C348 HydrophobicContact CE-CB 4.43Å; V301-C348 HydrophobicContact CG1-CB 4.46Å; E302-C348 CarbonylContact O-C 3.56Å; E302-C348 VanDerWaalsContact O-CA 3.27Å; E302-C348 WeakPolarHBondContact O-CA 3.3Å; C303-C348 HydrophobicContact CB-CB 4.23Å; C303-C348 WeakPolarHBondContact CB-SG 3.4Å; C303-C348 WeakPolarHBondContact SG-CB 3.43Å; C303-C348 CovalentContact SG-SG 2.05Å; C303-C348 PolarHBondContact SG-SG 3.28Å; C348-F350 HydrophobicContact CB-CE2 4.02Å; C348-F350 HydrophobicContact CB-CZ 3.97Å
349R97.3Very high94.7Very high48 Ų4828.8 Ų28.818%0.18117%0.17CC..EExtended strand (participates in β ladder)trans-117.6125.3179.3-63.8173.3172.8164.3-3.7109.9Y267 V268 E269 V301 E302Y267-R349 HydrophobicContact CD2-CB 3.86Å; Y267-R349 HydrophobicContact CD2-CG 3.71Å; Y267-R349 HydrophobicContact CE2-CB 4.4Å; Y267-R349 HydrophobicContact CE2-CG 3.79Å; Y267-R349 HydrophobicContact CG-CB 4.08Å; Y267-R349 HydrophobicContact CG-CG 4.36Å; V268-R349 CarbonylContact O-C 3.3Å; V268-R349 WeakPolarHBondContact O-CA 3.41Å; E269-R349 HydrophobicContact CB-CG 4.33Å; E269-R349 HydrophobicContact CG-CG 4.14Å; E269-R349 IonicContact OE2-CZ 3.46Å; E269-R349 IonicContact OE2-NE 3.77Å; E269-R349 PolarHBondContact OE2-NE 2.94Å; E269-R349 IonicContact OE2-NH2 3.16Å; E269-R349 PolarHBondContact OE2-NH2 3.23Å; V301-R349 VanDerWaalsContact CA-O 3.28Å; V301-R349 WeakPolarHBondContact CA-O 3.44Å; E302-R349 HydrophobicContact CB-CB 4.32Å; E302-R349 PolarHBondContact N-O 2.72Å; E302-R349 PolarHBondContact O-N 2.79Å; E302-R349 IonicContact OE1-NH1 3.78Å; E302-R349 PolarHBondContact OE1-NH1 3.25Å
350F97.1Very high95.1Very high0 Ų026 Ų260%014%0.14CC..EExtended strand (participates in β ladder)trans-106.9109.4-178.5-56.6-86.1000109.3Y267 V268 M270 M283 V285 P298 V301 C348 L357 F359Y267-F350 WeakPolarHBondContact CA-O 3.43Å; Y267-F350 VanDerWaalsContact CB-O 3.29Å; Y267-F350 WeakPolarHBondContact CB-O 3.38Å; V268-F350 PolarHBondContact N-O 3.26Å; V268-F350 PolarHBondContact O-N 2.94Å; M270-F350 HydrophobicContact CB-CE2 4.32Å; M270-F350 HydrophobicContact CG-CE2 4.14Å; M270-F350 HydrophobicContact SD-CD2 4.38Å; M270-F350 HydrophobicContact SD-CE2 3.77Å; M283-F350 HydrophobicContact CE-CE1 3.71Å; M283-F350 HydrophobicContact CE-CZ 3.8Å; M283-F350 HydrophobicContact SD-CZ 4.19Å; V285-F350 HydrophobicContact CG2-CE1 3.98Å; V285-F350 HydrophobicContact CG2-CZ 4.43Å; P298-F350 HydrophobicContact CB-CB 4.43Å; V301-F350 HydrophobicContact CB-CD1 4.45Å; V301-F350 HydrophobicContact CG1-CD1 3.94Å; V301-F350 HydrophobicContact CG1-CE1 3.76Å; V301-F350 HydrophobicContact CG1-CZ 4.42Å; V301-F350 HydrophobicContact CG2-CD1 3.7Å; V301-F350 HydrophobicContact CG2-CE1 4.03Å; C348-F350 HydrophobicContact CB-CE2 4.02Å; C348-F350 HydrophobicContact CB-CZ 3.97Å; F350-L357 HydrophobicContact CB-CD1 4.12Å; F350-L357 WeakPolarHBondContact O-CD1 3.49Å; F350-F359 HydrophobicContact CB-CE2 4.25Å; F350-F359 HydrophobicContact CB-CZ 3.85Å; F350-F359 HydrophobicContact CD1-CE2 4.03Å; F350-F359 AromaticContact CD1-CZ 3.79Å; F350-F359 HydrophobicContact CD1-CZ 3.79Å; F350-F359 AromaticContact CD2-CE2 3.96Å; F350-F359 HydrophobicContact CD2-CE2 3.96Å; F350-F359 HydrophobicContact CD2-CZ 4.36Å; F350-F359 HydrophobicContact CE1-CE2 4.41Å; F350-F359 HydrophobicContact CE1-CZ 4.47Å; F350-F359 HydrophobicContact CE2-CE2 4.33Å; F350-F359 AromaticContact CG-CE2 3.8Å; F350-F359 HydrophobicContact CG-CE2 3.8Å; F350-F359 AromaticContact CG-CZ 3.73Å; F350-F359 HydrophobicContact CG-CZ 3.73Å
351L96.1Very high95.3Very high47 Ų4724.2 Ų24.225%0.24612%0.122CC..EExtended strand (participates in β ladder)trans-75.9129.7-176.1-66.8162.2000110.8Y267 P298 G299 G300 A353Y267-L351 HydrophobicContact CD1-CD2 4.36Å; P298-L351 CarbonylContact C-O 3.53Å; P298-L351 VanDerWaalsContact CA-O 3.29Å; P298-L351 WeakPolarHBondContact CA-O 3.47Å; G299-L351 PolarHBondContact N-O 3.06Å; G300-L351 WeakPolarHBondContact O-CB 3.32Å; G300-L351 PolarHBondContact O-N 3.26Å; L351-A353 PolarHBondContact O-N 2.96Å
352F95.4Very high95.6Very high26 Ų2620.8 Ų20.811%0.11411%0.11CC..  trans-66130175.2-70.5-84.5000111.2W258 N260 F263 G266 V268 L357W258-F352 HydrophobicContact CB-CZ 4.2Å; W258-F352 WeakPolarHBondContact O-CE1 3.29Å; N260-F352 HydrophobicContact CB-CB 4.04Å; N260-F352 HydrophobicContact CB-CD1 3.67Å; N260-F352 HydrophobicContact CB-CD2 4.07Å; N260-F352 HydrophobicContact CB-CE1 4.11Å; N260-F352 HydrophobicContact CB-CE2 4.48Å; N260-F352 HydrophobicContact CB-CG 3.67Å; N260-F352 HydrophobicContact CB-CZ 4.5Å; N260-F352 VanDerWaalsContact OD1-CD2 3.26Å; N260-F352 WeakPolarHBondContact OD1-CD2 3.21Å; N260-F352 WeakPolarHBondContact OD1-CG 3.39Å; F263-F352 HydrophobicContact CB-CE2 3.88Å; F263-F352 HydrophobicContact CD2-CE2 4.14Å; F263-F352 AromaticContact CD2-CZ 3.98Å; F263-F352 HydrophobicContact CD2-CZ 3.98Å; F263-F352 HydrophobicContact CG-CE2 4.16Å; F263-F352 HydrophobicContact CG-CZ 4.45Å; G266-F352 PolarHBondContact O-N 3.43Å; V268-F352 HydrophobicContact CG2-CE1 4.34Å; V268-F352 HydrophobicContact CG2-CE2 3.96Å; V268-F352 HydrophobicContact CG2-CZ 3.54Å; F352-L357 HydrophobicContact CD1-CB 4.14Å; F352-L357 HydrophobicContact CD1-CD1 3.59Å; F352-L357 HydrophobicContact CD1-CG 3.53Å; F352-L357 HydrophobicContact CD2-CD1 4.33Å; F352-L357 HydrophobicContact CE1-CB 3.85Å; F352-L357 HydrophobicContact CE1-CD1 3.69Å; F352-L357 HydrophobicContact CE1-CG 3.73Å; F352-L357 HydrophobicContact CE2-CD1 4.41Å; F352-L357 HydrophobicContact CG-CD1 3.92Å; F352-L357 HydrophobicContact CG-CG 4.27Å; F352-L357 HydrophobicContact CZ-CD1 4.12Å
353A92.3Very high95.7Very high42 Ų4218.9 Ų18.935%0.34710%0.098SC..SBendtrans-110.90.9166.200000113.2R296 L297 L351R296-A353 VanDerWaalsContact CD-O 3.28Å; R296-A353 WeakPolarHBondContact CD-O 3.44Å; L297-A353 WeakPolarHBondContact O-CB 3.43Å; L351-A353 PolarHBondContact O-N 2.96Å
354G91Very high95.8Very high13 Ų1319.1 Ų19.113%0.13410%0.099CC..SBendtrans-154-179.117800000111.6W356G354-W356 PolarHBondContact O-N 3.38Å
355P95.3Very high95.8Very high61 Ų6117.3 Ų17.340%0.39610%0.095SC..SBendtrans-55.1-33.6177.4-28.936.1000114.7S259 N260 G294S259-P355 WeakPolarHBondContact CA-O 3.22Å; N260-P355 PolarHBondContact N-O 2.94Å; G294-P355 WeakPolarHBondContact O-CD 3.46Å
356W97.2Very high95.7Very high34 Ų3417.3 Ų17.313%0.12910%0.098CC..EExtended strand (participates in β ladder)trans-132.9145.3-178.8-69.386.9000113.2Q200 T201 M202 L210 W258 G294 R296 G354 L358Q200-W356 HydrophobicContact CB-CH2 4.09Å; Q200-W356 HydrophobicContact CB-CZ3 3.95Å; T201-W356 WeakPolarHBondContact O-CH2 3.39Å; M202-W356 HydrophobicContact CB-CH2 3.79Å; M202-W356 HydrophobicContact CB-CZ2 3.61Å; M202-W356 HydrophobicContact CB-CZ3 4.29Å; M202-W356 HydrophobicContact CE-CB 4.23Å; M202-W356 HydrophobicContact CE-CD2 3.71Å; M202-W356 HydrophobicContact CE-CE3 4.21Å; M202-W356 HydrophobicContact CE-CG 3.67Å; M202-W356 HydrophobicContact CG-CD2 4.42Å; M202-W356 HydrophobicContact CG-CH2 4.36Å; M202-W356 HydrophobicContact CG-CZ2 3.67Å; L210-W356 HydrophobicContact CD1-CE3 4.02Å; L210-W356 HydrophobicContact CD1-CZ3 3.86Å; W258-W356 WeakPolarHBondContact O-CA 3.32Å; G294-W356 PolarHBondContact O-N 3.09Å; R296-W356 PolarHBondContact N-O 3.04Å; R296-W356 VanDerWaalsContact N-O 3.16Å; G354-W356 PolarHBondContact O-N 3.38Å; W356-L358 HydrophobicContact CB-CD2 4.22Å; W356-L358 HydrophobicContact CE3-CD2 4.21Å
357L97.3Very high95.5Very high0 Ų021.4 Ų21.40%012%0.12CC..EExtended strand (participates in β ladder)trans-109.4126.2162.6-80.2170.6000108.3G257 W258 V268 P298 F350 F352 F359G257-L357 CarbonylContact C-O 3.6Å; G257-L357 WeakPolarHBondContact CA-O 3.4Å; W258-L357 HydrophobicContact CE3-CB 4.49Å; W258-L357 PolarHBondContact N-O 2.92Å; W258-L357 PolarHBondContact O-N 3.38Å; V268-L357 HydrophobicContact CG2-CD1 4.12Å; P298-L357 HydrophobicContact CB-CD2 3.78Å; P298-L357 HydrophobicContact CG-CD2 4.35Å; F350-L357 HydrophobicContact CB-CD1 4.12Å; F350-L357 WeakPolarHBondContact O-CD1 3.49Å; F352-L357 HydrophobicContact CD1-CB 4.14Å; F352-L357 HydrophobicContact CD1-CD1 3.59Å; F352-L357 HydrophobicContact CD1-CG 3.53Å; F352-L357 HydrophobicContact CD2-CD1 4.33Å; F352-L357 HydrophobicContact CE1-CB 3.85Å; F352-L357 HydrophobicContact CE1-CD1 3.69Å; F352-L357 HydrophobicContact CE1-CG 3.73Å; F352-L357 HydrophobicContact CE2-CD1 4.41Å; F352-L357 HydrophobicContact CG-CD1 3.92Å; F352-L357 HydrophobicContact CG-CG 4.27Å; F352-L357 HydrophobicContact CZ-CD1 4.12Å; L357-F359 HydrophobicContact CD2-CE1 4.13Å; L357-F359 HydrophobicContact CD2-CZ 4.31Å
358L98.1Very high95.3Very high1 Ų123.5 Ų23.51%0.00513%0.133CC..EExtended strand (participates in β ladder)trans-126.7124.7177.4-46-177.1000109.6M202 L210 F241 Y255 C287 N288 A295 W356M202-L358 HydrophobicContact CE-CD2 4.45Å; L210-L358 HydrophobicContact CD1-CD2 3.58Å; L210-L358 HydrophobicContact CD2-CD1 4.34Å; L210-L358 HydrophobicContact CD2-CD2 4.04Å; L210-L358 HydrophobicContact CG-CD2 4.29Å; F241-L358 HydrophobicContact CB-CD1 3.93Å; F241-L358 HydrophobicContact CD1-CD1 3.66Å; F241-L358 HydrophobicContact CD2-CD1 3.7Å; F241-L358 HydrophobicContact CE1-CD1 4Å; F241-L358 HydrophobicContact CE2-CD1 4.05Å; F241-L358 HydrophobicContact CG-CD1 3.48Å; F241-L358 VanDerWaalsContact CG-CD1 3.48Å; F241-L358 HydrophobicContact CZ-CD1 4.19Å; Y255-L358 HydrophobicContact CD1-CB 3.77Å; Y255-L358 HydrophobicContact CE1-CB 4.41Å; Y255-L358 HydrophobicContact CG-CB 4.29Å; C287-L358 WeakPolarHBondContact CA-O 3.27Å; N288-L358 HydrophobicContact CB-CB 3.94Å; N288-L358 HydrophobicContact CB-CD1 4.09Å; N288-L358 HydrophobicContact CB-CG 4.44Å; N288-L358 PolarHBondContact N-O 3.01Å; A295-L358 HydrophobicContact CB-CD1 3.65Å; A295-L358 HydrophobicContact CB-CG 3.91Å; W356-L358 HydrophobicContact CB-CD2 4.22Å; W356-L358 HydrophobicContact CE3-CD2 4.21Å
359F98.2Very high95Very high0 Ų025.8 Ų25.80%015%0.147CC..EExtended strand (participates in β ladder)trans-121141.4176.6-54.1-30000111.1L231 Y255 V256 W258 M270 V285 H286 C287 P298 F350 L357 I362L231-F359 HydrophobicContact CD2-CB 3.71Å; L231-F359 WeakPolarHBondContact CD2-O 3.48Å; Y255-F359 WeakPolarHBondContact CA-O 3.43Å; V256-F359 PolarHBondContact N-O 3.46Å; V256-F359 PolarHBondContact O-N 3.38Å; W258-F359 HydrophobicContact CH2-CD2 4.1Å; W258-F359 AromaticContact CZ3-CD2 3.63Å; W258-F359 HydrophobicContact CZ3-CD2 3.63Å; W258-F359 AromaticContact CZ3-CE2 4Å; W258-F359 HydrophobicContact CZ3-CE2 4Å; W258-F359 HydrophobicContact CZ3-CG 4.19Å; M270-F359 HydrophobicContact CE-CD2 3.99Å; M270-F359 HydrophobicContact CE-CE2 4.11Å; V285-F359 HydrophobicContact CG1-CB 4.14Å; V285-F359 HydrophobicContact CG1-CD1 3.6Å; V285-F359 HydrophobicContact CG1-CD2 4.05Å; V285-F359 HydrophobicContact CG1-CE1 4Å; V285-F359 HydrophobicContact CG1-CE2 4.4Å; V285-F359 HydrophobicContact CG1-CG 3.67Å; V285-F359 HydrophobicContact CG1-CZ 4.38Å; H286-F359 CarbonylContact O-C 3.52Å; H286-F359 VanDerWaalsContact O-CA 3.27Å; H286-F359 WeakPolarHBondContact O-CA 3.38Å; C287-F359 HydrophobicContact CB-CD1 4.3Å; C287-F359 VanDerWaalsContact SG-CD1 3.53Å; C287-F359 VanDerWaalsContact SG-CE1 3.51Å; P298-F359 HydrophobicContact CG-CE1 4.42Å; F350-F359 HydrophobicContact CB-CE2 4.25Å; F350-F359 HydrophobicContact CB-CZ 3.85Å; F350-F359 HydrophobicContact CD1-CE2 4.03Å; F350-F359 AromaticContact CD1-CZ 3.79Å; F350-F359 HydrophobicContact CD1-CZ 3.79Å; F350-F359 AromaticContact CD2-CE2 3.96Å; F350-F359 HydrophobicContact CD2-CE2 3.96Å; F350-F359 HydrophobicContact CD2-CZ 4.36Å; F350-F359 HydrophobicContact CE1-CE2 4.41Å; F350-F359 HydrophobicContact CE1-CZ 4.47Å; F350-F359 HydrophobicContact CE2-CE2 4.33Å; F350-F359 AromaticContact CG-CE2 3.8Å; F350-F359 HydrophobicContact CG-CE2 3.8Å; F350-F359 AromaticContact CG-CZ 3.73Å; F350-F359 HydrophobicContact CG-CZ 3.73Å; L357-F359 HydrophobicContact CD2-CE1 4.13Å; L357-F359 HydrophobicContact CD2-CZ 4.31Å; F359-I362 HydrophobicContact CD2-CD1 4.3Å
360S96.8Very high94Very high1 Ų129.4 Ų29.41%0.00717%0.17CC..EExtended strand (participates in β ladder)trans-95.5-46172.3-35.80000112.3Q230 L231 G237 D254 Y255 H286Q230-S360 CarbonylContact C-O 3.49Å; Q230-S360 VanDerWaalsContact O-O 3.08Å; L231-S360 WeakPolarHBondContact CA-O 3.45Å; G237-S360 WeakPolarHBondContact CA-OG 3.35Å; G237-S360 PolarHBondContact N-OG 2.88Å; G237-S360 VanDerWaalsContact N-OG 3.08Å; D254-S360 WeakPolarHBondContact O-CA 3.29Å; D254-S360 WeakPolarHBondContact O-CB 3.48Å; Y255-S360 WeakPolarHBondContact CD1-OG 3.46Å; Y255-S360 WeakPolarHBondContact CE1-OG 3.3Å; H286-S360 PolarHBondContact ND1-OG 2.9Å; H286-S360 PolarHBondContact O-N 3.02Å
361E95.9Very high91.9Very high0 Ų035.6 Ų35.60%020%0.203CC..EExtended strand (participates in β ladder)trans-148.9142.5-164.2168.17817500109M22 H25 F26 A232 D233 G234 V285 H286 S363M22-E361 HydrophobicContact CE-CB 4.3Å; M22-E361 HydrophobicContact CE-CG 3.53Å; H25-E361 IonicContact CE1-OE1 3.48Å; H25-E361 IonicContact ND1-OE1 2.76Å; H25-E361 PolarHBondContact ND1-OE1 3.45Å; H25-E361 VanDerWaalsContact ND1-OE1 3.1Å; F26-E361 WeakPolarHBondContact CE1-OE1 3.32Å; A232-E361 WeakPolarHBondContact CA-OE2 3.37Å; D233-E361 PolarHBondContact N-OE2 3.45Å; G234-E361 PolarHBondContact N-OE2 3.01Å; G234-E361 VanDerWaalsContact N-OE2 3.1Å; V285-E361 WeakPolarHBondContact CA-O 3.28Å; H286-E361 HydrophobicContact CB-CB 4.26Å; H286-E361 PolarHBondContact N-O 2.83Å; E361-S363 PolarHBondContact OE1-OG 2.78Å
362I96.5Very high89.1Confident3 Ų338.3 Ų38.32%0.01523%0.226CC..EExtended strand (participates in β ladder)trans-132.9116.8175.6-56.2-178.2000108.6L231 M270 F272 M283 Q284 V285 F359 F364L231-I362 HydrophobicContact CB-CD1 4.47Å; L231-I362 HydrophobicContact CB-CG1 4.39Å; L231-I362 HydrophobicContact CD1-CD1 4.22Å; L231-I362 PolarHBondContact O-N 2.87Å; M270-I362 HydrophobicContact CE-CD1 4.46Å; M270-I362 HydrophobicContact SD-CD1 3.81Å; F272-I362 HydrophobicContact CE1-CD1 4.14Å; F272-I362 HydrophobicContact CE1-CG2 3.98Å; F272-I362 HydrophobicContact CZ-CD1 3.93Å; F272-I362 HydrophobicContact CZ-CG2 4.16Å; M283-I362 HydrophobicContact CG-CG2 4.08Å; M283-I362 HydrophobicContact SD-CG2 4.09Å; Q284-I362 WeakPolarHBondContact O-CA 3.47Å; V285-I362 HydrophobicContact CG1-CG1 4.12Å; V285-I362 HydrophobicContact CG2-CG1 4.23Å; V285-I362 HydrophobicContact CG2-CG2 4.21Å; F359-I362 HydrophobicContact CD2-CD1 4.3Å; I362-F364 HydrophobicContact CG2-CE2 3.65Å; I362-F364 HydrophobicContact CG2-CZ 3.69Å
363S94.4Very high86.1Confident1 Ų142 Ų421%0.00726%0.255CS..EExtended strand (participates in β ladder)trans-126.2151.9178.7-25.80000112.2M22 G24 D189 Q284 E361M22-S363 VanDerWaalsContact CE-OG 3.29Å; M22-S363 WeakPolarHBondContact CE-OG 3.5Å; G24-S363 WeakPolarHBondContact O-CB 3.41Å; D189-S363 WeakPolarHBondContact OD2-CA 3.48Å; Q284-S363 PolarHBondContact N-O 3.3Å; Q284-S363 PolarHBondContact O-N 3.15Å; E361-S363 PolarHBondContact OE1-OG 2.78Å
364F95Very high83.5Confident5 Ų546.2 Ų46.22%0.02228%0.279CS..EExtended strand (participates in β ladder)trans-121.8117.6-171.8-63.8-89.5000112.4D189 L191 F272 F274 F280 M283 L338 L346 I362 S366D189-F364 PolarHBondContact OD2-N 3.23Å; L191-F364 HydrophobicContact CD1-CE2 4.4Å; L191-F364 HydrophobicContact CD2-CE2 4.38Å; F272-F364 HydrophobicContact CB-CZ 4.24Å; F272-F364 AromaticContact CD1-CE2 3.64Å; F272-F364 HydrophobicContact CD1-CE2 3.64Å; F272-F364 AromaticContact CD1-CZ 3.49Å; F272-F364 HydrophobicContact CD1-CZ 3.49Å; F272-F364 VanDerWaalsContact CD1-CZ 3.49Å; F272-F364 AromaticContact CD2-CZ 3.97Å; F272-F364 HydrophobicContact CD2-CZ 3.97Å; F272-F364 AromaticContact CE1-CE2 3.96Å; F272-F364 HydrophobicContact CE1-CE2 3.96Å; F272-F364 AromaticContact CE1-CZ 3.72Å; F272-F364 HydrophobicContact CE1-CZ 3.72Å; F272-F364 HydrophobicContact CE2-CZ 4.17Å; F272-F364 HydrophobicContact CG-CE2 4.15Å; F272-F364 AromaticContact CG-CZ 3.63Å; F272-F364 HydrophobicContact CG-CZ 3.63Å; F272-F364 HydrophobicContact CZ-CZ 4.06Å; F274-F364 HydrophobicContact CE1-CB 3.9Å; F274-F364 HydrophobicContact CE1-CD1 4.33Å; F274-F364 AromaticContact CE1-CD2 3.64Å; F274-F364 HydrophobicContact CE1-CD2 3.64Å; F274-F364 HydrophobicContact CE1-CE2 4.26Å; F274-F364 AromaticContact CE1-CG 3.69Å; F274-F364 HydrophobicContact CE1-CG 3.69Å; F274-F364 HydrophobicContact CZ-CB 4.19Å; F274-F364 AromaticContact CZ-CD1 3.75Å; F274-F364 HydrophobicContact CZ-CD1 3.75Å; F274-F364 AromaticContact CZ-CD2 3.54Å; F274-F364 HydrophobicContact CZ-CD2 3.54Å; F274-F364 AromaticContact CZ-CE1 3.96Å; F274-F364 HydrophobicContact CZ-CE1 3.96Å; F274-F364 AromaticContact CZ-CE2 3.77Å; F274-F364 HydrophobicContact CZ-CE2 3.77Å; F274-F364 AromaticContact CZ-CG 3.54Å; F274-F364 HydrophobicContact CZ-CG 3.54Å; F274-F364 AromaticContact CZ-CZ 3.98Å; F274-F364 HydrophobicContact CZ-CZ 3.98Å; F280-F364 HydrophobicContact CD1-CB 4.33Å; F280-F364 HydrophobicContact CD1-CD1 4.25Å; F280-F364 HydrophobicContact CE1-CB 4.17Å; F280-F364 HydrophobicContact CE1-CD1 4.26Å; F280-F364 HydrophobicContact CE1-CG 4.43Å; M283-F364 HydrophobicContact CB-CD1 3.85Å; M283-F364 HydrophobicContact CB-CE1 3.8Å; M283-F364 HydrophobicContact CG-CD1 3.96Å; M283-F364 HydrophobicContact CG-CE1 3.53Å; M283-F364 HydrophobicContact CG-CZ 4.01Å; M283-F364 HydrophobicContact SD-CD1 4.47Å; M283-F364 HydrophobicContact SD-CE1 3.49Å; M283-F364 WeakPolarHBondContact SD-CE1 3.36Å; M283-F364 HydrophobicContact SD-CZ 3.76Å; L338-F364 HydrophobicContact CD1-CD1 4.44Å; L346-F364 HydrophobicContact CD1-CD1 3.84Å; L346-F364 HydrophobicContact CD1-CE1 3.59Å; I362-F364 HydrophobicContact CG2-CE2 3.65Å; I362-F364 HydrophobicContact CG2-CZ 3.69Å; F364-S366 PolarHBondContact O-N 3.25Å
365I93.3Very high80.7Confident44 Ų4450.4 Ų50.423%0.22631%0.312CS..EExtended strand (participates in β ladder)trans-85.4104.3175.1-55.9177.9000107.7K23 Q281 A282K23-I365 HydrophobicContact CB-CD1 4.18Å; Q281-I365 HydrophobicContact CB-CG2 4.14Å; Q281-I365 WeakPolarHBondContact CB-O 3.23Å; Q281-I365 HydrophobicContact CG-CG2 4.48Å; Q281-I365 PolarHBondContact N-O 3.37Å; A282-I365 PolarHBondContact N-O 2.83Å; A282-I365 PolarHBondContact O-N 3.04Å
366S93.4Very high77.7Confident19 Ų1956.1 Ų56.113%0.13334%0.338CS..EExtended strand (participates in β ladder)trans-150.9149.8-174.169.70000114.4R278 A279 F364R278-S366 PolarHBondContact NH1-OG 2.71Å; A279-S366 VanDerWaalsContact O-CA 3.22Å; A279-S366 WeakPolarHBondContact O-CA 3.13Å; A279-S366 WeakPolarHBondContact O-CB 3.39Å; F364-S366 PolarHBondContact O-N 3.25Å
367D92.5Very high74.6Confident86 Ų8658.3 Ų58.346%0.4637%0.372SS..EExtended strand (participates in β ladder)trans-107142.2177.6-57.1-69.7000111.5R278 A279 Q281R278-D367 CarbonylContact C-O 3.5Å; R278-D367 WeakPolarHBondContact CA-O 3.32Å; A279-D367 PolarHBondContact N-O 2.85Å; A279-D367 PolarHBondContact O-N 2.96Å; A279-D367 VanDerWaalsContact O-N 3.08Å; Q281-D367 PolarHBondContact NE2-OD2 3.03Å
368V90.9Very high71.3Confident62 Ų6262.1 Ų62.138%0.37641%0.411SS..EExtended strand (participates in β ladder)trans-77.4127.9180176.70000111.2R276 R278R276-V368 HydrophobicContact CB-CG1 4.17Å; R276-V368 HydrophobicContact CG-CG1 4.45Å; R278-V368 HydrophobicContact CG-CG2 4.26Å
369V90.7Very high68.1Low49 Ų4968.1 Ų68.130%0.29745%0.448SS..  trans-94.6103.6-179.5-177.10000110.5L277 A279 V342L277-V369 HydrophobicContact CB-CB 4.43Å; L277-V369 PolarHBondContact O-N 2.93Å; A279-V369 HydrophobicContact CB-CG2 4.05Å; V342-V369 HydrophobicContact CG1-CB 4.39Å; V342-V369 HydrophobicContact CG1-CG2 3.95Å; V342-V369 HydrophobicContact CG2-CG2 4.08Å
370N77.5Confident64.7Low124 Ų12478 Ų7866%0.66349%0.491SS*.  trans-77121.5173.2-76.7-21.4000111S372N370-S372 PolarHBondContact O-N 3.1Å
371N51.8Low61.5Low130 Ų13083.3 Ų83.370%0.69553%0.526SS*.  trans-77.758.8178.5-107.416.9000112.4
372S38Very low58.9Low103 Ų10389.5 Ų89.572%0.7257%0.566SS**  trans-10154.8173.558.10000111.8N370N370-S372 PolarHBondContact O-N 3.1Å
373S31.4Very low55.6Low103 Ų10393.9 Ų93.972%0.7260%0.603SS**SBendtrans-156.7142.8167.5-78.10000109.3
374P37.7Very low52.8Low131 Ų13199.1 Ų99.185%0.85164%0.637SS**  trans-73.6143.2-167.529-35.4000113.1
375A32.4Very low49.5Very low101 Ų101110.1 Ų110.184%0.83568%0.678SS**  trans-74.6141.4177.100000112.2
376L33.3Very low46.3Very low181 Ų181120 Ų12095%0.94871%0.713SS**  trans-88.1113.3173.2-15382.4000110.5
377G31.1Very low43.3Very low80 Ų80124 Ų12483%0.82574%0.739SS**  trans42.499157.500000119.7
378G28Very low40.4Very low81 Ų81126.1 Ų126.184%0.83576%0.757SS**  trans-158.384.4168.100000112.8
379T30.8Very low37.5Very low126 Ų126126.1 Ų126.177%0.77377%0.769SS**  trans-86.5132.3-175.349.60000113.5
380F27.3Very low34.7Very low208 Ų208129.7 Ų129.791%0.91279%0.794SS**  trans-163164146.1-88.4-52.6000110.2
381P30Very low32.4Very low112 Ų112129.2 Ų129.273%0.72780%0.798SS**  trans-95.3167.6-151.237.1-39.2000116.9
382P41Very low31.3Very low131 Ų131128.9 Ų128.985%0.85180%0.802SS**  trans-97.3161.6-169.938.3-36.9000116.2
383A26.6Very low30.8Very low95 Ų95129.5 Ų129.579%0.78580%0.802SS**  trans-150.5166.6169.900000109.3
384P36.1Very low30.6Very low111 Ų111132.4 Ų132.472%0.72181%0.81SS**  -119144.1-91.27.415.2000116.9
385W26.5Very low30Very low235 Ų235135.3 Ų135.389%0.8981%0.809SS**  trans39.9110.2147.9-53.5101.1000122.2
386W24.6Very low29.7Very low251 Ų251135.7 Ų135.795%0.95181%0.806SS**  -141.3158.5128.4-114.3-88.9000107.3
387P31.1Very low29.4Very low105 Ų105132.4 Ų132.468%0.68280%0.798SS**PPolyproline II helixtrans-86.8157.6-163.534.9-31.6000113.7
388P31.5Very low29.1Very low129 Ų129136.3 Ų136.384%0.83880%0.799SS**PPolyproline II helixtrans-77.5139.9-179.731.7-35000112.9
389G30.9Very low29.2Very low62 Ų62141.1 Ų141.164%0.63980%0.8SS**PPolyproline II helixtrans-74.1167.115700000111.6
390P31.7Very low28.9Very low124 Ų124141.9 Ų141.981%0.80580%0.798SS**PPolyproline II helixtrans-65.2151.3179.728.6-35.2000111.9
391P28.4Very low28.8Very low115 Ų115139.7 Ų139.775%0.74779%0.791SS**PPolyproline II helixtrans-69.8139.9-178.729.2-34.8000111.4T393P391-T393 PolarHBondContact O-N 2.83Å
392P29.5Very low28.8Very low122 Ų122139 Ų13979%0.79279%0.787SS**PPolyproline II helixtrans-63.7135.7166.528.3-33.2000109.5
393T27.6Very low28.1Very low117 Ų117142.6 Ų142.672%0.71878%0.783SS**PPolyproline II helixtrans-68143.6178.641.90000111.4P391 F395P391-T393 PolarHBondContact O-N 2.83Å; T393-F395 PolarHBondContact O-N 3.44Å
394N26.2Very low28.3Very low164 Ų164142.1 Ų142.188%0.87779%0.787SS**  trans-55.8112.2175.8-73.4-21.3000111.3
395F25.5Very low28.1Very low192 Ų192145.8 Ų145.884%0.84280%0.795SS**  trans-103112.4152.9-89.6-88.6000108.4T393T393-F395 PolarHBondContact O-N 3.44Å
396S25.8Very low28.6Very low109 Ų109138.4 Ų138.476%0.76277%0.77SS**  trans-60.6137.3175.4-58.60000110.2L398S396-L398 PolarHBondContact O-N 3.34Å
397S26.4Very low29.4Very low111 Ų111130 Ų13078%0.77675%0.748SS**  trans-64.897.2176.450.50000111.2E399S397-E399 PolarHBondContact O-N 3.48Å
398L26.5Very low30.1Very low163 Ų163128.9 Ų128.985%0.85374%0.739SS**  trans-78.2101.1159-81.6168.2000107.9S396 L400S396-L398 PolarHBondContact O-N 3.34Å; L398-L400 PolarHBondContact O-N 3.26Å; L398-L400 VanDerWaalsContact O-N 3.09Å
399E29.1Very low30.5Very low182 Ų182123.4 Ų123.485%0.8571%0.705SS**  trans-66.8104.4171-65.1-179.6126.900108.9S397 E401S397-E399 PolarHBondContact O-N 3.48Å; E399-E401 PolarHBondContact O-N 2.9Å
400L25Very low30.8Very low141 Ų141129.2 Ų129.274%0.73871%0.712SS**  trans-85.598171.8-126.876.2000109.3L398L398-L400 PolarHBondContact O-N 3.26Å; L398-L400 VanDerWaalsContact O-N 3.09Å
401E25.8Very low31Very low162 Ų162127.3 Ų127.376%0.75771%0.707SS**  trans-54.4145.2158.7-91.7-69.3107.900110.1E399 R403E399-E401 PolarHBondContact O-N 2.9Å; E401-R403 PolarHBondContact O-N 3.28Å
402P28.3Very low31.4Very low99 Ų99130.9 Ų130.964%0.64371%0.714SS**  trans-64.5106.1-174.7-19.732.5000111.8G404P402-G404 PolarHBondContact O-N 3.35Å; P402-G404 VanDerWaalsContact O-N 3.17Å
403R28.1Very low31.7Very low206 Ų206127.8 Ų127.878%0.77770%0.703SS**  trans-62.2119169-75-177.5170.4-177.5-2.6108.5E401 Q405E401-R403 PolarHBondContact O-N 3.28Å; R403-Q405 PolarHBondContact O-N 3.4Å
404G30.3Very low32.4Very low84 Ų84124.6 Ų124.687%0.86669%0.686SS**THydrogen-bonded Turntrans-70.145.4-172.600000116.2P402P402-G404 PolarHBondContact O-N 3.35Å; P402-G404 VanDerWaalsContact O-N 3.17Å
405Q31.7Very low33.8Very low189 Ų189121.3 Ų121.388%0.88367%0.673SS**THydrogen-bonded Turntrans-141.513.2179.9-68.2-172.2-33.300113.4R403R403-Q405 PolarHBondContact O-N 3.4Å
406Q35.9Very low35.1Very low80 Ų80116.1 Ų116.137%0.37466%0.658SS.*  trans-66.3138.3170.9-82.8-170.1-49.200111.3D39 V408D39-Q406 PolarHBondContact OD2-NE2 3.33Å; D39-Q406 VanDerWaalsContact OD2-NE2 3.15Å; Q406-V408 PolarHBondContact O-N 3.27Å
407P42.3Very low36.3Very low75 Ų75113.9 Ų113.949%0.48765%0.646SS.*  trans-71.8114.5178.229-33.4000110.7
408V45.8Very low37.9Very low80 Ų80114 Ų11449%0.48564%0.637SS.*BIsolated β-bridgetrans-80132.6167.2179.60000108.6Y33 Q406 K410Y33-V408 HydrophobicContact CD1-CG2 4.08Å; Y33-V408 HydrophobicContact CE1-CG2 4.09Å; Q406-V408 PolarHBondContact O-N 3.27Å; V408-K410 PolarHBondContact O-N 2.95Å
409A40.4Very low39.7Very low15 Ų15111.8 Ų111.812%0.12463%0.625CS.*  trans-63.998.7172.200000109.9L99 L152 Y183 A411L99-A409 HydrophobicContact CD2-CB 4.18Å; L152-A409 HydrophobicContact CD1-CB 4.14Å; Y183-A409 HydrophobicContact CD1-CB 3.93Å; Y183-A409 HydrophobicContact CE1-CB 3.94Å; Y183-A409 HydrophobicContact CG-CB 4.41Å; A409-A411 PolarHBondContact O-N 3.49Å
410K36.3Very low41.8Very low184 Ų184108.3 Ų108.380%0.861%0.611SS**  trans-63125.9171.4-72.1-178179176.60108.4V408 E412V408-K410 PolarHBondContact O-N 2.95Å; K410-E412 PolarHBondContact O-N 3.33Å
411A35.8Very low44.2Very low83 Ų83103.6 Ų103.669%0.68660%0.596SS**  trans-58.4131.616400000108.7A409 G413A409-A411 PolarHBondContact O-N 3.49Å; A411-G413 PolarHBondContact O-N 3.43Å
412E36.7Very low46.8Very low191 Ų19199 Ų9989%0.89358%0.582SS**  trans-71.484.9172.4-69.5-153.1134.500109.7K410 S414K410-E412 PolarHBondContact O-N 3.33Å; E412-S414 PolarHBondContact O-N 3.35Å
413G35.6Very low49.4Very low56 Ų5699.5 Ų99.558%0.57758%0.578SS**  trans-6289.5159.700000108.2A411A411-G413 PolarHBondContact O-N 3.43Å
414S43.9Very low52.3Low50 Ų5093.2 Ų93.235%0.3556%0.563SS.*  trans-43.7135.6-172.1172.30000111.6E412 T416 A417E412-S414 PolarHBondContact O-N 3.35Å; S414-T416 PolarHBondContact O-N 3.07Å; S414-T416 PolarHBondContact OG-N 3.39Å; S414-T416 PolarHBondContact OG-OG1 2.97Å; S414-A417 WeakPolarHBondContact O-CB 3.28Å; S414-A417 PolarHBondContact O-N 2.91Å
415P54.4Low54.9Low95 Ų9592 Ų9262%0.61754%0.544SS*.Hα-helixtrans-57.8-20.8178.223.8-33.7000112.5I418 L419P415-I418 PolarHBondContact O-N 3.44Å; P415-L419 VanDerWaalsContact O-CB 3.31Å; P415-L419 WeakPolarHBondContact O-CB 3.32Å; P415-L419 WeakPolarHBondContact O-CG 3.37Å; P415-L419 PolarHBondContact O-N 3.29Å
416T53.3Low57.8Low83 Ų8387.5 Ų87.551%0.50953%0.525SS..Hα-helixtrans-62.7-38.1171.862.20000112.8S414 L419 I420S414-T416 PolarHBondContact O-N 3.07Å; S414-T416 PolarHBondContact OG-N 3.39Å; S414-T416 PolarHBondContact OG-OG1 2.97Å; T416-L419 PolarHBondContact O-N 3.33Å; T416-I420 WeakPolarHBondContact O-CB 3.12Å; T416-I420 WeakPolarHBondContact O-CD1 3.46Å; T416-I420 WeakPolarHBondContact O-CG1 3.45Å; T416-I420 PolarHBondContact O-N 3.06Å
417A49.7Very low60.4Low62 Ų6287.7 Ų87.751%0.51253%0.528SS..Hα-helixtrans-68.1-40.4179.700000111.8S414 G421S414-A417 WeakPolarHBondContact O-CB 3.28Å; S414-A417 PolarHBondContact O-N 2.91Å; A417-G421 PolarHBondContact O-N 3.44Å
418I60.9Low62.8Low115 Ų11589.3 Ų89.359%0.5953%0.532SS*.Hα-helixtrans-68.1-44.2175.2-58177.7000110.1P415 I420 G421 C422P415-I418 PolarHBondContact O-N 3.44Å; I418-I420 PolarHBondContact O-N 2.81Å; I418-G421 PolarHBondContact O-N 3.2Å; I418-C422 WeakPolarHBondContact O-CB 3.43Å; I418-C422 PolarHBondContact O-N 3.25Å; I418-C422 PolarHBondContact O-SG 3.25Å; I418-C422 VanDerWaalsContact O-SG 3.38Å
419L63.7Low65Low116 Ų11690.3 Ų90.361%0.60753%0.534SS*.Hα-helixtrans-59.3-45175.1-83.4163.7000112.3P415 T416 C422 L423P415-L419 VanDerWaalsContact O-CB 3.31Å; P415-L419 WeakPolarHBondContact O-CB 3.32Å; P415-L419 WeakPolarHBondContact O-CG 3.37Å; P415-L419 PolarHBondContact O-N 3.29Å; T416-L419 PolarHBondContact O-N 3.33Å; L419-C422 PolarHBondContact O-N 3.22Å; L419-L423 WeakPolarHBondContact O-CB 3.27Å; L419-L423 PolarHBondContact O-N 3.37Å
420I74.6Confident67.4Low108 Ų10894 Ų9455%0.55455%0.551SS**Hα-helixtrans-62.9-45.2176.2-70.7162.5000110.4T416 I418 C422 L423 V424T416-I420 WeakPolarHBondContact O-CB 3.12Å; T416-I420 WeakPolarHBondContact O-CD1 3.46Å; T416-I420 WeakPolarHBondContact O-CG1 3.45Å; T416-I420 PolarHBondContact O-N 3.06Å; I418-I420 PolarHBondContact O-N 2.81Å; I420-C422 PolarHBondContact O-N 3.32Å; I420-L423 PolarHBondContact O-N 3.31Å; I420-V424 HydrophobicContact CG2-CG2 4.34Å; I420-V424 WeakPolarHBondContact O-CB 3.1Å; I420-V424 WeakPolarHBondContact O-CG2 3.1Å; I420-V424 PolarHBondContact O-N 2.99Å
421G74.3Confident70.1Confident42 Ų4289.9 Ų89.943%0.43354%0.537SS..Hα-helixtrans-58-45.3175.400000112.8A417 I418 A425A417-G421 PolarHBondContact O-N 3.44Å; I418-G421 PolarHBondContact O-N 3.2Å; G421-A425 WeakPolarHBondContact O-CB 3.39Å; G421-A425 PolarHBondContact O-N 3.13Å
422C81Confident72.9Confident66 Ų6690.9 Ų90.945%0.44653%0.53SS..Hα-helixtrans-64.1-41.8174-70.50000112.5I418 L419 I420 A425 I426I418-C422 WeakPolarHBondContact O-CB 3.43Å; I418-C422 PolarHBondContact O-N 3.25Å; I418-C422 PolarHBondContact O-SG 3.25Å; I418-C422 VanDerWaalsContact O-SG 3.38Å; L419-C422 PolarHBondContact O-N 3.22Å; I420-C422 PolarHBondContact O-N 3.32Å; C422-A425 PolarHBondContact O-N 3.08Å; C422-I426 WeakPolarHBondContact O-CB 3.42Å; C422-I426 WeakPolarHBondContact O-CD1 3.13Å; C422-I426 VanDerWaalsContact O-CG1 3.25Å; C422-I426 WeakPolarHBondContact O-CG1 3.49Å; C422-I426 PolarHBondContact O-N 2.76Å
423L81.7Confident75.6Confident110 Ų11085.5 Ų85.558%0.57651%0.507SS*.Hα-helixtrans-64.2-45179.2-148.391.4000111.2L419 I420 I426 I427L419-L423 WeakPolarHBondContact O-CB 3.27Å; L419-L423 PolarHBondContact O-N 3.37Å; I420-L423 PolarHBondContact O-N 3.31Å; L423-I426 PolarHBondContact O-N 2.54Å; L423-I427 HydrophobicContact CD2-CD1 4.25Å; L423-I427 HydrophobicContact CG-CD1 4.39Å; L423-I427 WeakPolarHBondContact O-CD1 3.42Å; L423-I427 VanDerWaalsContact O-CG1 3.26Å; L423-I427 WeakPolarHBondContact O-CG1 3.24Å; L423-I427 PolarHBondContact O-N 3.47Å
424V89Confident78.3Confident74 Ų7487 Ų8745%0.44850%0.501SS..Hα-helixtrans-62.5-43.5175.6170.60000110.8I420 I426 I427 L428I420-V424 HydrophobicContact CG2-CG2 4.34Å; I420-V424 WeakPolarHBondContact O-CB 3.1Å; I420-V424 WeakPolarHBondContact O-CG2 3.1Å; I420-V424 PolarHBondContact O-N 2.99Å; V424-I426 PolarHBondContact O-N 2.72Å; V424-I427 PolarHBondContact O-N 2.82Å; V424-L428 HydrophobicContact CG1-CD1 3.91Å; V424-L428 HydrophobicContact CG1-CG 4.39Å; V424-L428 WeakPolarHBondContact O-CB 3.44Å; V424-L428 VanDerWaalsContact O-CG 3.31Å; V424-L428 WeakPolarHBondContact O-CG 3.26Å; V424-L428 PolarHBondContact O-N 3.25Å
425A85.2Confident80.6Confident57 Ų5787.2 Ų87.247%0.47151%0.505SS..Hα-helixtrans-61.5-41.2175.600000112.5G421 C422 L428 L429G421-A425 WeakPolarHBondContact O-CB 3.39Å; G421-A425 PolarHBondContact O-N 3.13Å; C422-A425 PolarHBondContact O-N 3.08Å; A425-L428 PolarHBondContact O-N 2.81Å; A425-L429 WeakPolarHBondContact O-CB 3.21Å; A425-L429 PolarHBondContact O-N 2.91Å
426I92.3Very high82.3Confident96 Ų9687.5 Ų87.549%0.49250%0.502SS..Hα-helixtrans-65.6-43.3175.7-70163.4000111.1C422 L423 V424 L429 L430C422-I426 WeakPolarHBondContact O-CB 3.42Å; C422-I426 WeakPolarHBondContact O-CD1 3.13Å; C422-I426 VanDerWaalsContact O-CG1 3.25Å; C422-I426 WeakPolarHBondContact O-CG1 3.49Å; C422-I426 PolarHBondContact O-N 2.76Å; L423-I426 PolarHBondContact O-N 2.54Å; V424-I426 PolarHBondContact O-N 2.72Å; I426-L429 PolarHBondContact O-N 3.12Å; I426-L430 HydrophobicContact CG2-CD1 3.98Å; I426-L430 HydrophobicContact CG2-CG 4.5Å; I426-L430 WeakPolarHBondContact O-CB 3.46Å; I426-L430 WeakPolarHBondContact O-CG 3.42Å; I426-L430 PolarHBondContact O-N 2.84Å
427I92.4Very high84Confident84 Ų8489.1 Ų89.143%0.43151%0.505SS..Hα-helixtrans-62.1-45.2176.8-70.5163.6000110.8L423 V424 L429 L430 L431L423-I427 HydrophobicContact CD2-CD1 4.25Å; L423-I427 HydrophobicContact CG-CD1 4.39Å; L423-I427 WeakPolarHBondContact O-CD1 3.42Å; L423-I427 VanDerWaalsContact O-CG1 3.26Å; L423-I427 WeakPolarHBondContact O-CG1 3.24Å; L423-I427 PolarHBondContact O-N 3.47Å; V424-I427 PolarHBondContact O-N 2.82Å; I427-L429 PolarHBondContact O-N 2.92Å; I427-L430 PolarHBondContact O-N 3.37Å; I427-L431 HydrophobicContact CG2-CD1 3.98Å; I427-L431 HydrophobicContact CG2-CG 4.48Å; I427-L431 WeakPolarHBondContact O-CB 3.32Å; I427-L431 VanDerWaalsContact O-CG 3.31Å; I427-L431 WeakPolarHBondContact O-CG 3.3Å; I427-L431 PolarHBondContact O-N 3.04Å
428L90.7Very high85.9Confident108 Ų10891.3 Ų91.357%0.56551%0.507SS*.Hα-helixtrans-63.7-39176.5-70.9171.2000112.2V424 A425 L431 L432V424-L428 HydrophobicContact CG1-CD1 3.91Å; V424-L428 HydrophobicContact CG1-CG 4.39Å; V424-L428 WeakPolarHBondContact O-CB 3.44Å; V424-L428 VanDerWaalsContact O-CG 3.31Å; V424-L428 WeakPolarHBondContact O-CG 3.26Å; V424-L428 PolarHBondContact O-N 3.25Å; A425-L428 PolarHBondContact O-N 2.81Å; L428-L431 PolarHBondContact O-N 2.86Å; L428-L432 WeakPolarHBondContact O-CB 3.33Å; L428-L432 PolarHBondContact O-N 3.37Å
429L92.8Very high87.1Confident102 Ų10293.7 Ų93.753%0.53451%0.509SS..Hα-helixtrans-64.7-42.8175.1-167.576.6000111.7A425 I426 I427 L432 I433A425-L429 WeakPolarHBondContact O-CB 3.21Å; A425-L429 PolarHBondContact O-N 2.91Å; I426-L429 PolarHBondContact O-N 3.12Å; I427-L429 PolarHBondContact O-N 2.92Å; L429-L432 WeakPolarHBondContact O-CB 3.36Å; L429-L432 PolarHBondContact O-N 2.04Å; L429-I433 HydrophobicContact CG-CD1 4.21Å; L429-I433 VanDerWaalsContact O-CG1 3.29Å; L429-I433 WeakPolarHBondContact O-CG1 3.38Å; L429-I433 PolarHBondContact O-N 2.83Å
430L91.9Very high88.1Confident92 Ų9296.1 Ų96.148%0.48251%0.51SS..Hα-helixtrans-64.4-42.5175.7-73.1168.6000111.7I426 I427 L432 I433 I434I426-L430 HydrophobicContact CG2-CD1 3.98Å; I426-L430 HydrophobicContact CG2-CG 4.5Å; I426-L430 WeakPolarHBondContact O-CB 3.46Å; I426-L430 WeakPolarHBondContact O-CG 3.42Å; I426-L430 PolarHBondContact O-N 2.84Å; I427-L430 PolarHBondContact O-N 3.37Å; L430-L432 VanDerWaalsContact C-N 3.34Å; L430-L432 PolarHBondContact O-N 3.1Å; L430-I433 PolarHBondContact O-N 3.32Å; L430-I434 WeakPolarHBondContact O-CB 3.27Å; L430-I434 VanDerWaalsContact O-CG1 3.27Å; L430-I434 WeakPolarHBondContact O-CG1 3.45Å; L430-I434 PolarHBondContact O-N 3.02Å
431L93.2Very high88.3Confident98 Ų9895.4 Ų95.451%0.51351%0.507SS..Hα-helixtrans-62.7-39.4174.4-72.2171000112I427 L428 I434 A435I427-L431 HydrophobicContact CG2-CD1 3.98Å; I427-L431 HydrophobicContact CG2-CG 4.48Å; I427-L431 WeakPolarHBondContact O-CB 3.32Å; I427-L431 VanDerWaalsContact O-CG 3.31Å; I427-L431 WeakPolarHBondContact O-CG 3.3Å; I427-L431 PolarHBondContact O-N 3.04Å; L428-L431 PolarHBondContact O-N 2.86Å; L431-I434 PolarHBondContact O-N 3.41Å; L431-A435 VanDerWaalsContact O-CB 3.29Å; L431-A435 WeakPolarHBondContact O-CB 3.3Å; L431-A435 PolarHBondContact O-N 3.33Å
432L93.6Very high88.6Confident103 Ų10398.6 Ų98.654%0.53951%0.51SS..Hα-helixtrans-62.6-44.4173.4-170.878.6000111.6L428 L429 L430 A435 L436L428-L432 WeakPolarHBondContact O-CB 3.33Å; L428-L432 PolarHBondContact O-N 3.37Å; L429-L432 WeakPolarHBondContact O-CB 3.36Å; L429-L432 PolarHBondContact O-N 2.04Å; L430-L432 VanDerWaalsContact C-N 3.34Å; L430-L432 PolarHBondContact O-N 3.1Å; L432-A435 PolarHBondContact O-N 2.89Å; L432-L436 HydrophobicContact CG-CD1 4.2Å; L432-L436 WeakPolarHBondContact O-CB 3.39Å; L432-L436 VanDerWaalsContact O-CG 3.3Å; L432-L436 WeakPolarHBondContact O-CG 3.3Å; L432-L436 PolarHBondContact O-N 3.24Å
433I93.4Very high88.3Confident79 Ų79101.2 Ų101.241%0.40551%0.511SS..Hα-helixtrans-64-43.4177.6-69.6163.1000110.8L429 L430 L436 M437L429-I433 HydrophobicContact CG-CD1 4.21Å; L429-I433 VanDerWaalsContact O-CG1 3.29Å; L429-I433 WeakPolarHBondContact O-CG1 3.38Å; L429-I433 PolarHBondContact O-N 2.83Å; L430-I433 PolarHBondContact O-N 3.32Å; I433-L436 PolarHBondContact O-N 2.87Å; I433-M437 HydrophobicContact CG2-SD 4.31Å; I433-M437 WeakPolarHBondContact O-CB 3.46Å; I433-M437 WeakPolarHBondContact O-CG 3.47Å; I433-M437 PolarHBondContact O-N 3.04Å
434I93.1Very high87.9Confident88 Ų88103.6 Ų103.645%0.45151%0.512SS..Hα-helixtrans-62.6-44.9175.3-69.2164000110.4L430 L431 L436 M437 L438L430-I434 WeakPolarHBondContact O-CB 3.27Å; L430-I434 VanDerWaalsContact O-CG1 3.27Å; L430-I434 WeakPolarHBondContact O-CG1 3.45Å; L430-I434 PolarHBondContact O-N 3.02Å; L431-I434 PolarHBondContact O-N 3.41Å; I434-L436 PolarHBondContact O-N 3.3Å; I434-M437 PolarHBondContact O-N 3.03Å; I434-L438 HydrophobicContact CG2-CD1 3.88Å; I434-L438 HydrophobicContact CG2-CG 4.34Å; I434-L438 WeakPolarHBondContact O-CB 3.26Å; I434-L438 VanDerWaalsContact O-CG 3.31Å; I434-L438 WeakPolarHBondContact O-CG 3.4Å; I434-L438 PolarHBondContact O-N 2.8Å
435A91.3Very high87Confident53 Ų53109 Ų10944%0.43852%0.524SS..Hα-helixtrans-60.9-42.517600000112L431 L432 L438 W439L431-A435 VanDerWaalsContact O-CB 3.29Å; L431-A435 WeakPolarHBondContact O-CB 3.3Å; L431-A435 PolarHBondContact O-N 3.33Å; L432-A435 PolarHBondContact O-N 2.89Å; A435-L438 PolarHBondContact O-N 2.91Å; A435-W439 WeakPolarHBondContact O-CB 3.2Å; A435-W439 PolarHBondContact O-N 3.44Å
436L91.3Very high86.2Confident102 Ų102110 Ų11053%0.53452%0.522SS..Hα-helixtrans-66.7-37.2175.1-72.9169.1000112.6L432 I433 I434 R440L432-L436 HydrophobicContact CG-CD1 4.2Å; L432-L436 WeakPolarHBondContact O-CB 3.39Å; L432-L436 VanDerWaalsContact O-CG 3.3Å; L432-L436 WeakPolarHBondContact O-CG 3.3Å; L432-L436 PolarHBondContact O-N 3.24Å; I433-L436 PolarHBondContact O-N 2.87Å; I434-L436 PolarHBondContact O-N 3.3Å; L436-R440 VanDerWaalsContact O-CB 3.25Å; L436-R440 WeakPolarHBondContact O-CB 3.29Å; L436-R440 PolarHBondContact O-N 3.1Å
437M89Confident84.9Confident117 Ų117110.1 Ų110.158%0.57652%0.523SS*.Hα-helixtrans-65.7-45.6173-76.7-178.264.200111.6I433 I434 R440 L441I433-M437 HydrophobicContact CG2-SD 4.31Å; I433-M437 WeakPolarHBondContact O-CB 3.46Å; I433-M437 WeakPolarHBondContact O-CG 3.47Å; I433-M437 PolarHBondContact O-N 3.04Å; I434-M437 PolarHBondContact O-N 3.03Å; M437-R440 PolarHBondContact O-N 2.96Å; M437-L441 WeakPolarHBondContact O-CB 3.27Å; M437-L441 WeakPolarHBondContact O-CD1 3.5Å; M437-L441 VanDerWaalsContact O-CG 3.27Å; M437-L441 WeakPolarHBondContact O-CG 3.49Å; M437-L441 PolarHBondContact O-N 3.25Å
438L88.1Confident83.3Confident108 Ų108108.4 Ų108.457%0.56552%0.518SS*.Hα-helixtrans-64.4-40.8176.1-70.7173.4000111.6I434 A435 L441 H442I434-L438 HydrophobicContact CG2-CD1 3.88Å; I434-L438 HydrophobicContact CG2-CG 4.34Å; I434-L438 WeakPolarHBondContact O-CB 3.26Å; I434-L438 VanDerWaalsContact O-CG 3.31Å; I434-L438 WeakPolarHBondContact O-CG 3.4Å; I434-L438 PolarHBondContact O-N 2.8Å; A435-L438 PolarHBondContact O-N 2.91Å; L438-L441 PolarHBondContact O-N 3.08Å; L438-H442 VanDerWaalsContact O-CB 3.27Å; L438-H442 WeakPolarHBondContact O-CB 3.5Å; L438-H442 PolarHBondContact O-N 3.41Å
439W86.8Confident81.7Confident165 Ų165110.4 Ų110.463%0.62552%0.522SS*.Hα-helixtrans-61.5-44.7173.1-176.9-98.4000111.7A435 H442 W443A435-W439 WeakPolarHBondContact O-CB 3.2Å; A435-W439 PolarHBondContact O-N 3.44Å; W439-H442 PolarHBondContact O-N 3.39Å; W439-W443 AromaticContact CD1-CD1 3.8Å; W439-W443 AromaticContact CE2-CD1 3.51Å; W439-W443 AromaticContact CE2-NE1 3.39Å; W439-W443 AromaticContact CZ2-CD1 3.97Å; W439-W443 AromaticContact CZ2-NE1 3.34Å; W439-W443 VanDerWaalsContact CZ2-NE1 3.34Å; W439-W443 AromaticContact NE1-CD1 3.37Å; W439-W443 AromaticContact NE1-NE1 3.54Å; W439-W443 WeakPolarHBondContact O-CB 3.33Å; W439-W443 PolarHBondContact O-N 3.46Å
440R85.1Confident79.8Confident167 Ų167108.1 Ų108.163%0.6352%0.518SS*.Hα-helixtrans-67.1-35.1176.4-165.5179.4-169-1635.2112.4L436 M437 R444L436-R440 VanDerWaalsContact O-CB 3.25Å; L436-R440 WeakPolarHBondContact O-CB 3.29Å; L436-R440 PolarHBondContact O-N 3.1Å; M437-R440 PolarHBondContact O-N 2.96Å; R440-R444 WeakPolarHBondContact O-CB 3.45Å; R440-R444 VanDerWaalsContact O-CG 3.3Å; R440-R444 WeakPolarHBondContact O-CG 3.43Å; R440-R444 PolarHBondContact O-N 3.4Å
441L77.9Confident77.9Confident92 Ų92110.4 Ų110.448%0.48253%0.526SS..Hα-helixtrans-69.5-38.7172.4-76.4163.5000111.8M437 L438 R445M437-L441 WeakPolarHBondContact O-CB 3.27Å; M437-L441 WeakPolarHBondContact O-CD1 3.5Å; M437-L441 VanDerWaalsContact O-CG 3.27Å; M437-L441 WeakPolarHBondContact O-CG 3.49Å; M437-L441 PolarHBondContact O-N 3.25Å; L438-L441 PolarHBondContact O-N 3.08Å; L441-R445 WeakPolarHBondContact O-CB 3.49Å; L441-R445 WeakPolarHBondContact O-CG 3.46Å; L441-R445 PolarHBondContact O-N 3.16Å
442H80Confident75.8Confident109 Ų109114.6 Ų114.651%0.50554%0.535SS..Hα-helixtrans-66-46.8175.4-170.990.6000111L438 W439 R445 L446L438-H442 VanDerWaalsContact O-CB 3.27Å; L438-H442 WeakPolarHBondContact O-CB 3.5Å; L438-H442 PolarHBondContact O-N 3.41Å; W439-H442 PolarHBondContact O-N 3.39Å; H442-R445 CarbonylContact O-C 3.6Å; H442-R445 WeakPolarHBondContact O-CB 3.27Å; H442-R445 PolarHBondContact O-N 3.05Å; H442-R445 VanDerWaalsContact O-N 3.15Å; H442-L446 PolarHBondContact O-N 3.16Å
443W75Confident73.6Confident121 Ų121119.7 Ų119.746%0.45855%0.547SS..Hα-helixtrans-63.9-39.2174-93.898.4000113.4W439 R445 L446 L447W439-W443 AromaticContact CD1-CD1 3.8Å; W439-W443 AromaticContact CE2-CD1 3.51Å; W439-W443 AromaticContact CE2-NE1 3.39Å; W439-W443 AromaticContact CZ2-CD1 3.97Å; W439-W443 AromaticContact CZ2-NE1 3.34Å; W439-W443 VanDerWaalsContact CZ2-NE1 3.34Å; W439-W443 AromaticContact NE1-CD1 3.37Å; W439-W443 AromaticContact NE1-NE1 3.54Å; W439-W443 WeakPolarHBondContact O-CB 3.33Å; W439-W443 PolarHBondContact O-N 3.46Å; W443-R445 VanDerWaalsContact C-N 3.33Å; W443-R445 PolarHBondContact O-N 2.77Å; W443-L446 HydrophobicContact CD2-CD1 4.46Å; W443-L446 PolarHBondContact O-N 2.92Å; W443-L447 HydrophobicContact CE3-CD1 4.43Å; W443-L447 HydrophobicContact CE3-CG 4.31Å; W443-L447 WeakPolarHBondContact O-CB 3.33Å; W443-L447 WeakPolarHBondContact O-CG 3.26Å; W443-L447 PolarHBondContact O-N 2.78Å
444R74.4Confident71.5Confident160 Ų160120.5 Ų120.560%0.60456%0.556SS**Hα-helixtrans-61.2-40.9170.3-81.2178.3167.8-164.9-5.8112R440 S448R440-R444 WeakPolarHBondContact O-CB 3.45Å; R440-R444 VanDerWaalsContact O-CG 3.3Å; R440-R444 WeakPolarHBondContact O-CG 3.43Å; R440-R444 PolarHBondContact O-N 3.4Å; R444-S448 WeakPolarHBondContact O-CB 3.46Å; R444-S448 PolarHBondContact O-N 2.92Å; R444-S448 PolarHBondContact O-OG 3.42Å
445R70.6Confident69.4Low187 Ų187121.9 Ų121.971%0.70656%0.563SS**Hα-helixtrans-65.6-39.9174.6-76.9176.8174.2-171.3-1.1112.2L441 H442 W443 S448 K449L441-R445 WeakPolarHBondContact O-CB 3.49Å; L441-R445 WeakPolarHBondContact O-CG 3.46Å; L441-R445 PolarHBondContact O-N 3.16Å; H442-R445 CarbonylContact O-C 3.6Å; H442-R445 WeakPolarHBondContact O-CB 3.27Å; H442-R445 PolarHBondContact O-N 3.05Å; H442-R445 VanDerWaalsContact O-N 3.15Å; W443-R445 VanDerWaalsContact C-N 3.33Å; W443-R445 PolarHBondContact O-N 2.77Å; R445-S448 WeakPolarHBondContact CA-OG 3.44Å; R445-S448 PolarHBondContact O-OG 3.46Å; R445-K449 WeakPolarHBondContact O-CG 3.48Å; R445-K449 PolarHBondContact O-N 2.7Å; R445-K449 VanDerWaalsContact O-N 3.16Å
446L67.4Low67.2Low80 Ų80126.9 Ų126.942%0.41958%0.577SS.*Hα-helixtrans-63.1-49.9173.7-78.4167.7000112H442 W443 S448 K449 A450H442-L446 PolarHBondContact O-N 3.16Å; W443-L446 HydrophobicContact CD2-CD1 4.46Å; W443-L446 PolarHBondContact O-N 2.92Å; L446-S448 PolarHBondContact O-N 3.03Å; L446-K449 CarbonylContact O-C 3.5Å; L446-K449 WeakPolarHBondContact O-CA 3.32Å; L446-K449 WeakPolarHBondContact O-CB 3.49Å; L446-K449 PolarHBondContact O-N 3.16Å; L446-A450 PolarHBondContact O-N 2.97Å
447L64.1Low65.1Low98 Ų98129.9 Ų129.951%0.51359%0.589SS.*Hα-helixtrans-61.1-43.6177.9-72.1164.4000111.7W443 K449 A450 E451W443-L447 HydrophobicContact CE3-CD1 4.43Å; W443-L447 HydrophobicContact CE3-CG 4.31Å; W443-L447 WeakPolarHBondContact O-CB 3.33Å; W443-L447 WeakPolarHBondContact O-CG 3.26Å; W443-L447 PolarHBondContact O-N 2.78Å; L447-K449 PolarHBondContact O-N 3.43Å; L447-K449 VanDerWaalsContact O-N 3.15Å; L447-A450 WeakPolarHBondContact O-CA 3.05Å; L447-A450 WeakPolarHBondContact O-CB 3.34Å; L447-A450 PolarHBondContact O-N 3.39Å; L447-E451 PolarHBondContact O-N 3.33Å
448S60.5Low62.9Low47 Ų47131.7 Ų131.733%0.32960%0.596SS.*Hα-helixtrans-64.3-18.2174.271.30000114.4R444 R445 L446 R452R444-S448 WeakPolarHBondContact O-CB 3.46Å; R444-S448 PolarHBondContact O-N 2.92Å; R444-S448 PolarHBondContact O-OG 3.42Å; R445-S448 WeakPolarHBondContact CA-OG 3.44Å; R445-S448 PolarHBondContact O-OG 3.46Å; L446-S448 PolarHBondContact O-N 3.03Å; S448-R452 WeakPolarHBondContact O-CB 3.45Å; S448-R452 WeakPolarHBondContact O-CD 3.39Å; S448-R452 VanDerWaalsContact O-CG 3.25Å; S448-R452 WeakPolarHBondContact O-CG 3.46Å
449K56.4Low60.5Low151 Ų151133.3 Ų133.366%0.65760%0.604SS**Hα-helixtrans-90.5-19171.4-78.3-177173.1-170.30112.8R445 L446 L447R445-K449 WeakPolarHBondContact O-CG 3.48Å; R445-K449 PolarHBondContact O-N 2.7Å; R445-K449 VanDerWaalsContact O-N 3.16Å; L446-K449 CarbonylContact O-C 3.5Å; L446-K449 WeakPolarHBondContact O-CA 3.32Å; L446-K449 WeakPolarHBondContact O-CB 3.49Å; L446-K449 PolarHBondContact O-N 3.16Å; L447-K449 PolarHBondContact O-N 3.43Å; L447-K449 VanDerWaalsContact O-N 3.15Å
450A53.2Low58.2Low54 Ų54131.3 Ų131.345%0.44661%0.611SS.*Hα-helixtrans-77.5-51.1169.500000110.4L446 L447 R452 R453 V454L446-A450 PolarHBondContact O-N 2.97Å; L447-A450 WeakPolarHBondContact O-CA 3.05Å; L447-A450 WeakPolarHBondContact O-CB 3.34Å; L447-A450 PolarHBondContact O-N 3.39Å; A450-R452 VanDerWaalsContact C-N 3.32Å; A450-R452 PolarHBondContact O-N 3.35Å; A450-R453 PolarHBondContact O-N 2.92Å; A450-V454 PolarHBondContact O-N 3.19Å
451E52.2Low56Low140 Ų140127.9 Ų127.965%0.65461%0.608SS**Hα-helixtrans-56.6-44176.8-70.7176.6127.400112.1L447 R453 V454 L455L447-E451 PolarHBondContact O-N 3.33Å; E451-R453 PolarHBondContact O-N 3.23Å; E451-V454 PolarHBondContact O-N 3.45Å; E451-L455 PolarHBondContact O-N 2.84Å
452R48.4Very low54Low185 Ų185132 Ų13270%0.69863%0.625SS**Hα-helixtrans-65.6-19.2178.1-76.3-178.5-179.3-158.1-1.8114.7S448 A450S448-R452 WeakPolarHBondContact O-CB 3.45Å; S448-R452 WeakPolarHBondContact O-CD 3.39Å; S448-R452 VanDerWaalsContact O-CG 3.25Å; S448-R452 WeakPolarHBondContact O-CG 3.46Å; A450-R452 VanDerWaalsContact C-N 3.32Å; A450-R452 PolarHBondContact O-N 3.35Å
453R47.3Very low51.6Low210 Ų210134.7 Ų134.779%0.79264%0.641SS**Hα-helixtrans-85.8-15172.2-80.2-172.2173.3-167.4-2.1113.9A450 E451A450-R453 PolarHBondContact O-N 2.92Å; E451-R453 PolarHBondContact O-N 3.23Å
454V49.8Very low49.5Very low97 Ų97134.8 Ų134.859%0.58866%0.661SS**Hα-helixtrans-93.3-38175.4179.90000110.3A450 E451 E456A450-V454 PolarHBondContact O-N 3.19Å; E451-V454 PolarHBondContact O-N 3.45Å; V454-E456 PolarHBondContact O-N 2.87Å
455L47.9Very low47.4Very low116 Ų116133.8 Ų133.861%0.60767%0.672SS**Hα-helixtrans-77.4-17.2-175.2-151.572.8000114.7E451E451-L455 PolarHBondContact O-N 2.84Å
456E45.4Very low46Very low158 Ų158130.7 Ų130.774%0.73868%0.676SS**Hα-helixtrans-79.2-14.6176.5-77.3-176.8157.700113.6V454V454-E456 PolarHBondContact O-N 2.87Å
457E46.4Very low44.2Very low165 Ų165130.2 Ų130.277%0.77169%0.691SS**Hα-helixtrans-88.4-29.6174.8-68.5-168133.900113.4
458E43.7Very low42.6Very low156 Ų156132.6 Ų132.673%0.72970%0.704SS**Hα-helixtrans-92.2-17.6-175.6-73.9-165.313200115.7
459L37.3Very low41.1Very low142 Ų142136.1 Ų136.174%0.74372%0.724SS**  trans-101.330.9-173.6-145.374.3000115.1V461L459-V461 VanDerWaalsContact C-N 3.31Å
460T39.6Very low40Very low123 Ų123136.3 Ų136.376%0.75573%0.73SS**SBendtrans-89.314.9172.440.60000113.9
461V37.5Very low38.9Very low94 Ų94140.7 Ų140.757%0.5775%0.745SS**  trans-132.1141.8-176.5-152.50000112.6L459L459-V461 VanDerWaalsContact C-N 3.31Å
462H35.7Very low38.2Very low180 Ų180141 Ų14183%0.83375%0.75SS**  trans82.8117.6174.3-59.1-70.4000118.7
463L31.3Very low37.4Very low164 Ų164138 Ų13886%0.85975%0.748SS**  trans-97.7174178.9-59.286.9000112.5
464S30Very low36.6Very low123 Ų123135.5 Ų135.586%0.8675%0.75SS**  trans116.2148.4142.6760000119.3
465V31Very low35.6Very low139 Ų139141 Ų14184%0.84276%0.76SS**  trans-166.6157.7-159153.60000107.1
466P41.3Very low35.5Very low122 Ų122141.4 Ų141.479%0.79277%0.77SS**  cis-122.7-157.73.643.8-29.4000113.5
467G28.3Very low34.6Very low71 Ų71137.1 Ų137.173%0.73277%0.769SS**  trans157.582.7153.700000119.8
468D30.3Very low34.8Very low148 Ų148134.8 Ų134.879%0.79177%0.768SS**  trans34.6115.4135.9-71.525.3000126
469T30.7Very low34.2Very low120 Ų120137 Ų13774%0.73677%0.77SS**  79152.3121.3-34.10000123.9
470I32.9Very low33.8Very low155 Ų155137 Ų13780%0.79577%0.765SS**  trans90.2145.6160.8-57-175.4000117.9
471L29.1Very low34.4Very low146 Ų146136.5 Ų136.576%0.76477%0.765SS**  cis-177.8176.1-42.1-129.6170.8000110.2
472I37.6Very low35.7Very low147 Ų147137.2 Ų137.275%0.75477%0.771SS**  trans76127.9169.2-51.3-178.6000116.1
473N31.4Very low37Very low122 Ų122133.3 Ų133.365%0.65276%0.762SS**  cis104.9129.59.6-171.617.4000116.5
474N30.4Very low37.2Very low158 Ų158135.8 Ų135.885%0.84576%0.761SS**  trans-157.4113.8152-107.1-28.1000116.5
475R30.7Very low37.3Very low211 Ų211138.5 Ų138.580%0.79676%0.76SS**  trans-20.3177.2147.6-72.7174.6171.9179-2.1120
476P44.9Very low37.4Very low125 Ų125137.8 Ų137.881%0.81275%0.748SS**  cis-135.1-1769.829.2-4.4000117.6
477G27.3Very low37.7Very low69 Ų69137.6 Ų137.671%0.71175%0.746SS**  trans-99.4-13916600000112.8
478P49.7Very low37.9Very low116 Ų116143.4 Ų143.475%0.75375%0.746SS**  cis-153.4-168.27.947.1-26.7000118.4
479R32Very low39.2Very low203 Ų203141.8 Ų141.877%0.76674%0.744SS**  trans81.6143.4147.8-77.7-164.8155.9132.57.1122.6
480E29.1Very low39.1Very low140 Ų140148.1 Ų148.165%0.65476%0.755SS**  cis-171.2-151.9-17.4-131.1168.3-137.200109.3
481P52.3Low38.8Very low114 Ų114144.3 Ų144.374%0.7475%0.753SS**  -102.6-78.8-75.715.13.6000122
482P63.6Low38.8Very low108 Ų108145 Ų14570%0.70176%0.758SS**  trans-133.1-150.4-14546.7-26.3000113.9
483P63.8Low39.9Very low98 Ų98143 Ų14364%0.63675%0.754SS**  cis-141.2164.3-10.340.4-20.9000119.8
484Y35.8Very low40.8Very low216 Ų216141.6 Ų141.685%0.84775%0.752SS**  trans52.5149.9149-63.2-50.7000123.7
485Q31.2Very low40.9Very low180 Ų180142.8 Ų142.884%0.84175%0.752SS**  cis-154.8-173.212.5-136.7167.312.600113.4
486E33.3Very low40.9Very low124 Ų124138 Ų13858%0.57975%0.751SS**  trans-144.5173.3178.4-127.1-153.6-112.500110.5R488E486-R488 IonicContact OE1-CZ 2.94Å; E486-R488 IonicContact OE1-NE 2.73Å; E486-R488 IonicContact OE1-NH2 2.8Å; E486-R488 PolarHBondContact OE1-NH2 3.26Å; E486-R488 WeakPolarHBondContact OE2-CG 3.23Å; E486-R488 IonicContact OE2-CZ 2.91Å; E486-R488 IonicContact OE2-NE 3.24Å; E486-R488 PolarHBondContact OE2-NE 3.03Å; E486-R488 IonicContact OE2-NH2 3.62Å; E486-R488 PolarHBondContact OE2-NH2 3.4Å
487P46.9Very low40.2Very low118 Ų118136.3 Ų136.377%0.76675%0.747SS**  cis-148.6-118.944.742.4-16.7000118.9
488R32.8Very low40.9Very low193 Ų193138.7 Ų138.773%0.72875%0.75SS**  trans-154.2-170.1-155.1-38.3179.7-163.5-166.1-0.5110.4E486E486-R488 IonicContact OE1-CZ 2.94Å; E486-R488 IonicContact OE1-NE 2.73Å; E486-R488 IonicContact OE1-NH2 2.8Å; E486-R488 PolarHBondContact OE1-NH2 3.26Å; E486-R488 WeakPolarHBondContact OE2-CG 3.23Å; E486-R488 IonicContact OE2-CZ 2.91Å; E486-R488 IonicContact OE2-NE 3.24Å; E486-R488 PolarHBondContact OE2-NE 3.03Å; E486-R488 IonicContact OE2-NH2 3.62Å; E486-R488 PolarHBondContact OE2-NH2 3.4Å
489P56.7Low39.9Very low115 Ų115138.5 Ų138.575%0.74775%0.75SS**  cis-143-157.7-7.745.1-24.2000116.1
490R29.6Very low39.8Very low253 Ų253135.1 Ų135.196%0.95575%0.752SS**  trans84.4132.6156.7-91.1-175.1175.1-178.9-0.7122.9
491G26.5Very low40.7Very low74 Ų74132.9 Ų132.976%0.76375%0.75SS**  trans167.6142.4162.700000113.9
492N29.7Very low39.6Very low161 Ų161135.2 Ų135.286%0.86176%0.756SS**  trans-175.3168.8-179.3-138.118.8000112
493P60.8Low37.8Very low105 Ų105134 Ų13468%0.68276%0.763SS**  cis-108-100.6-27.231.3-9.8000110.1
494P50.2Low36.1Very low93 Ų93135 Ų13560%0.60477%0.772SS**  cis-129.5176.1-16.843.8-27.5000116.8
495H33Very low35.8Very low182 Ų182128.5 Ų128.584%0.84376%0.763SS**  trans58.8146.3162.2-65.2-59.6000120.4
496S29.5Very low35.6Very low112 Ų112130.5 Ų130.578%0.78377%0.765SS**  cis-165.3156.1-9.946.40000112.1
497A30.4Very low35.3Very low88 Ų88129.9 Ų129.973%0.72777%0.774SS**  trans-123.8163.417100000111.8
498P42.7Very low34.5Very low120 Ų120127.1 Ų127.178%0.77977%0.767SS**  -137.7153.4111.516.36.2000112.9
499C27.3Very low34.2Very low111 Ų111124.3 Ų124.375%0.7577%0.767SS**  79.6113.850.6-69.80000113.7
500V29.6Very low33Very low132 Ų132129.7 Ų129.780%0.877%0.774SS**  99.4147.966.3137.80000111.5
501P49.3Very low32.9Very low94 Ų94126.5 Ų126.561%0.6177%0.772SS**  cis-149.6-162.1-21.744.4-23.8000116.8
502N28.3Very low33.1Very low163 Ų163130.9 Ų130.987%0.87277%0.773SS**  trans79.7144.9144.8-74.3-1.6000124.1
503G27.1Very low33.5Very low82 Ų82129.1 Ų129.185%0.84577%0.77SS**  trans17761.7176.100000115.9
504S28.3Very low31.9Very low118 Ų118130.5 Ų130.583%0.82577%0.767SS**  trans-75164.2172.546.80000113.4
505A28.1Very low31.4Very low81 Ų81133.9 Ų133.967%0.66977%0.772SS**  cis-172.6-150.9-11.700000108.2
506Y27.6Very low31.6Very low221 Ų221131.6 Ų131.687%0.86777%0.773SS**  trans78.6143.6174-69.9-83.1000117.2
507S27.9Very low31.6Very low111 Ų111129.6 Ų129.678%0.77677%0.77SS**  cis-160.1162.7-6.4-157.80000112.4
508G28.4Very low31.6Very low61 Ų61130.3 Ų130.363%0.62978%0.777SS**  trans108.583.8136.600000120.4
509D27.5Very low31.2Very low133 Ų133130.8 Ų130.871%0.71178%0.78SS**  trans18.1138.3132.3-44.4-33.9000121.7
510Y30.6Very low31.8Very low228 Ų228133.7 Ų133.789%0.89479%0.787SS**  -169.917298.2-97.6-63.5000112.9
511M28.7Very low31.8Very low187 Ų187135.5 Ų135.592%0.92179%0.791SS**  trans-95.6156.3-158.5-89.8-177.8148.500117.6
512E31.2Very low31.3Very low166 Ų166136.1 Ų136.178%0.77680%0.795SS**  trans-90.9154.7166.4178.1-178.9-156.900111.8
513P37.3Very low31.4Very low123 Ų123134 Ų13480%0.79979%0.79SS**  trans-117.4142.9158.936-25.9000113.3
514E27.3Very low31.6Very low134 Ų134135.8 Ų135.863%0.62679%0.787SS**  trans-100.6151.9-163.5-50.3-165.9114.500117.8
515K38.6Very low32.2Very low165 Ų165136 Ų13672%0.71779%0.785SS**  trans67166.9135.8-78.5164.7-164.2159.20118.5
516P37.2Very low32.1Very low133 Ų133141.1 Ų141.186%0.86480%0.796SS**  cis-113.8-166.711.842-29000114.6
517G30.2Very low32.3Very low70 Ų70138.3 Ų138.372%0.72280%0.796SS**  trans-152.8-175.5-173.400000117.4
518A31.5Very low32.2Very low104 Ų104138.4 Ų138.486%0.8680%0.796SS**  trans68.7150.9-172.600000115.6
519P33.5Very low32Very low129 Ų129140.9 Ų140.984%0.83880%0.799SS**  cis-119.9-179.81142-29.5000115.8
520L38.8Very low32Very low172 Ų172139.4 Ų139.490%0.90180%0.797SS**  trans-82.2133.5175.5-70.7158.8000112.7
521L30.2Very low31.8Very low170 Ų170137.5 Ų137.589%0.8980%0.796SS**  trans-164.1163.6151.1-97.6172.1000108.1
522P39.6Very low31.7Very low107 Ų107137.1 Ų137.170%0.69579%0.785SS**  trans-100.1154.1-149.837.2-38.2000117.1
523P29.6Very low31.4Very low119 Ų119133.5 Ų133.577%0.77378%0.784SS**  trans-90.4150.2160.336-31.8000112.4
524P31.1Very low30.8Very low119 Ų119137.1 Ų137.177%0.77379%0.79SS**  trans-103.2-164.4177.545.3-39000111.8
525P40.8Very low30.7Very low122 Ų122134.1 Ų134.179%0.79279%0.788SS**  -82.3147.5-124.838.7-26000115.1
526Q25.8Very low30.1Very low190 Ų190132.3 Ų132.389%0.88879%0.786SS**  trans-136.4136.5163.7-70.4-168.2-1600112.2S528Q526-S528 PolarHBondContact O-N 2.8Å; Q526-S528 VanDerWaalsContact O-N 3.12Å
527N32.8Very low29.7Very low162 Ų162128.7 Ų128.787%0.86676%0.759SS**  trans-38.4100.6-172.4-58-18.2000116.3V529N527-V529 PolarHBondContact O-N 3.26Å
528S26.1Very low29.6Very low112 Ų112130.9 Ų130.978%0.78376%0.758SS**  trans-72.5103.1150.958.20000109Q526Q526-S528 PolarHBondContact O-N 2.8Å; Q526-S528 VanDerWaalsContact O-N 3.12Å
529V24.6Very low29.5Very low113 Ų113131.4 Ų131.469%0.68575%0.75SS**PPolyproline II helixtrans-61128.5166.6179.40000107.3N527 H531N527-V529 PolarHBondContact O-N 3.26Å; V529-H531 PolarHBondContact O-N 3.1Å
530P26.8Very low29.3Very low103 Ų103126.4 Ų126.467%0.66972%0.717SS**PPolyproline II helixtrans-59.1129177.2-24.134.2000110.3Y532P530-Y532 PolarHBondContact O-N 3.36Å
531H26.3Very low29Very low188 Ų188126.5 Ų126.587%0.8771%0.713SS**PPolyproline II helixtrans-56.4117167.8-76.6-94.9000107.9V529 A533V529-H531 PolarHBondContact O-N 3.1Å; H531-A533 PolarHBondContact O-N 3.39Å
532Y25.9Very low29.2Very low179 Ų179119.8 Ų119.870%0.70268%0.684SS**PPolyproline II helixtrans-60.5138.5174.7-93.1-99.5000109P530P530-Y532 PolarHBondContact O-N 3.36Å
533A25.8Very low28.9Very low90 Ų90115.4 Ų115.474%0.74466%0.655SS**PPolyproline II helixtrans-53.3147.9-167.400000113.1H531 A535H531-A533 PolarHBondContact O-N 3.39Å; A533-A535 VanDerWaalsContact C-N 3.32Å; A533-A535 PolarHBondContact O-N 2.9Å
534E24.8Very low28.9Very low198 Ų198115.2 Ų115.293%0.92565%0.652SS**  trans-58.597.5163.1-68.7-177111.300108.8D536E534-D536 PolarHBondContact O-N 3.32Å; E534-D536 VanDerWaalsContact O-N 3.14Å
535A25.1Very low29.1Very low71 Ų71110.4 Ų110.459%0.58762%0.624SS**  trans-65.9112.3165.600000107.1A533 I537A533-A535 VanDerWaalsContact C-N 3.32Å; A533-A535 PolarHBondContact O-N 2.9Å; A535-I537 PolarHBondContact O-N 2.95Å
536D25.3Very low29.1Very low127 Ų127105.7 Ų105.768%0.67960%0.598SS**  trans-69.2102.3172.9-136.4-23.3000107.8E534 V538 R765E534-D536 PolarHBondContact O-N 3.32Å; E534-D536 VanDerWaalsContact O-N 3.14Å; D536-V538 WeakPolarHBondContact O-CG2 3.26Å; D536-V538 PolarHBondContact O-N 2.79Å; D536-R765 IonicContact OD1-CZ 3.13Å; D536-R765 IonicContact OD1-NH2 3.6Å; D536-R765 PolarHBondContact OD1-NH2 3.18Å
537I29.5Very low29.9Very low58 Ų5897.9 Ų97.930%0.29756%0.562SS.*  trans-73.382.3-179.3-55.9174.3000107.4A535 T539 L540 R765A535-I537 PolarHBondContact O-N 2.95Å; I537-T539 PolarHBondContact O-N 2.97Å; I537-T539 VanDerWaalsContact O-N 3.13Å; I537-L540 HydrophobicContact CG2-CD1 3.82Å; I537-L540 HydrophobicContact CG2-CG 4.41Å; I537-R765 WeakPolarHBondContact O-CD 3.37Å; I537-R765 PolarHBondContact O-NE 3.33Å
538V27.3Very low30.7Very low115 Ų11590.3 Ų90.370%0.69752%0.522SS*.  trans-59.2113.3-176.2174.60000110.2D536 L540D536-V538 WeakPolarHBondContact O-CG2 3.26Å; D536-V538 PolarHBondContact O-N 2.79Å; V538-L540 PolarHBondContact O-N 3.48Å
539T29.1Very low31.5Very low115 Ų11586 Ų8671%0.70649%0.488SS*.  trans19.886.6163.955.70000116.5I537 Q541I537-T539 PolarHBondContact O-N 2.97Å; I537-T539 VanDerWaalsContact O-N 3.13Å; T539-Q541 PolarHBondContact O-N 3.35Å
540L30.4Very low32.4Very low24 Ų2481.4 Ų81.413%0.12646%0.462CS..  trans-64.386.8172-75145.8000112.1I537 V538 G542 V543 A766 L768 F783I537-L540 HydrophobicContact CG2-CD1 3.82Å; I537-L540 HydrophobicContact CG2-CG 4.41Å; V538-L540 PolarHBondContact O-N 3.48Å; L540-G542 PolarHBondContact O-N 3.33Å; L540-V543 HydrophobicContact CB-CG2 3.79Å; L540-A766 HydrophobicContact CB-CB 3.87Å; L540-A766 HydrophobicContact CD1-CB 4.14Å; L540-L768 HydrophobicContact CD1-CD1 3.76Å; L540-L768 HydrophobicContact CD1-CD2 4.1Å; L540-L768 HydrophobicContact CD1-CG 4.15Å; L540-L768 HydrophobicContact CD2-CD2 4.31Å; L540-F783 HydrophobicContact CD2-CE2 3.91Å; L540-F783 HydrophobicContact CD2-CZ 4.45Å
541Q31.8Very low32.8Very low175 Ų17581.2 Ų81.282%0.81846%0.459SS*.THydrogen-bonded Turntrans-67.394.2169.7-77-168.6-16.300110.4T539 R728T539-Q541 PolarHBondContact O-N 3.35Å; Q541-R728 PolarHBondContact O-NH1 3.03Å
542G34.7Very low33.1Very low28 Ų2873.5 Ų73.529%0.28943%0.426SS..THydrogen-bonded Turntrans152.8-0.4177.100000116.6L540L540-G542 PolarHBondContact O-N 3.33Å
543V32.8Very low33.4Very low15 Ų1569.9 Ų69.99%0.09143%0.433CS..SBendtrans-135.41.8-177.3-100.70000114.9L540 G545 A766 V767 L768L540-V543 HydrophobicContact CB-CG2 3.79Å; V543-G545 VanDerWaalsContact C-N 3.33Å; V543-G545 PolarHBondContact O-N 3.13Å; V543-A766 HydrophobicContact CB-CB 3.93Å; V543-A766 HydrophobicContact CG2-CB 3.45Å; V543-A766 VanDerWaalsContact CG2-CB 3.45Å; V543-V767 WeakPolarHBondContact CB-O 3.15Å; V543-V767 VanDerWaalsContact CG1-O 3.27Å; V543-V767 WeakPolarHBondContact CG1-O 3.19Å; V543-L768 HydrophobicContact CG2-CD2 4.01Å
544T30.9Very low33.6Very low116 Ų11669.4 Ų69.471%0.71242%0.417SS*.SBendtrans-84.35.317843.20000115.1A766T544-A766 HydrophobicContact CG2-CB 4.19Å
545G35.3Very low33.7Very low18 Ų1865.1 Ų65.119%0.18641%0.407CS..SBendtrans-175.3123.2169.600000114.2V543 N547V543-G545 VanDerWaalsContact C-N 3.33Å; V543-G545 PolarHBondContact O-N 3.13Å; G545-N547 VanDerWaalsContact C-N 3.25Å; G545-N547 PolarHBondContact O-N 2.87Å
546G40.3Very low33.9Very low23 Ų2367 Ų6724%0.23741%0.413CS..SBendtrans68.5-56.9159.300000118.3
547N42.8Very low34.2Very low25 Ų2564.1 Ų64.113%0.13441%0.413CS..  trans-113.1159-161.5-48.3-0000109.6G545 D631 R752G545-N547 VanDerWaalsContact C-N 3.25Å; G545-N547 PolarHBondContact O-N 2.87Å; N547-D631 PolarHBondContact ND2-O 2.95Å; N547-R752 PolarHBondContact O-NH2 2.84Å
548T48.3Very low34.2Very low3 Ų365.9 Ų65.92%0.01844%0.437CS..  trans-124.6-19.3-177.1-32.60000113.1H727 R728 D729 D747 R752T548-H727 WeakPolarHBondContact CG2-O 3.34Å; T548-R728 HydrophobicContact CG2-CB 3.85Å; T548-R728 WeakPolarHBondContact O-CD 3.43Å; T548-R728 WeakPolarHBondContact O-CG 3.46Å; T548-D729 HydrophobicContact CG2-CB 3.31Å; T548-D747 WeakPolarHBondContact CA-OD2 3.32Å; T548-D747 WeakPolarHBondContact CB-OD1 3.49Å; T548-D747 WeakPolarHBondContact CB-OD2 3.46Å; T548-D747 PolarHBondContact N-OD2 3.48Å; T548-D747 PolarHBondContact OG1-OD1 3.38Å; T548-D747 PolarHBondContact OG1-OD2 3.27Å; T548-R752 PolarHBondContact OG1-NH2 3.42Å
549Y44.7Very low34.7Very low22 Ų2267.6 Ų67.69%0.08645%0.447CS..PPolyproline II helixtrans-62.1141.6-178.2-61.3-41.6000116.5I638 F725 H727 D747Y549-I638 HydrophobicContact CD2-CD1 4.5Å; Y549-I638 HydrophobicContact CD2-CG2 3.8Å; Y549-I638 HydrophobicContact CE2-CG2 4.18Å; Y549-I638 HydrophobicContact CG-CG2 4.48Å; Y549-F725 VanDerWaalsContact CB-CZ 3.4Å; Y549-F725 HydrophobicContact CD1-CD1 4.5Å; Y549-F725 AromaticContact CD1-CE1 3.32Å; Y549-F725 HydrophobicContact CD1-CE1 3.32Å; Y549-F725 AromaticContact CD1-CZ 3.46Å; Y549-F725 HydrophobicContact CD1-CZ 3.46Å; Y549-F725 VanDerWaalsContact CD1-CZ 3.46Å; Y549-F725 HydrophobicContact CD2-CE1 4.41Å; Y549-F725 AromaticContact CD2-CZ 3.75Å; Y549-F725 HydrophobicContact CD2-CZ 3.75Å; Y549-F725 AromaticContact CE1-CE1 3.76Å; Y549-F725 HydrophobicContact CE1-CE1 3.76Å; Y549-F725 HydrophobicContact CE1-CZ 4.06Å; Y549-F725 HydrophobicContact CE2-CZ 4.29Å; Y549-F725 AromaticContact CG-CE1 3.69Å; Y549-F725 HydrophobicContact CG-CE1 3.69Å; Y549-F725 HydrophobicContact CG-CE2 4.26Å; Y549-F725 AromaticContact CG-CZ 3.27Å; Y549-F725 HydrophobicContact CG-CZ 3.27Å; Y549-H727 AromaticContact CE1-CE1 3.94Å; Y549-H727 AromaticContact CE1-NE2 3.9Å; Y549-D747 HydrophobicContact CD1-CB 4.35Å; Y549-D747 HydrophobicContact CD2-CB 4.25Å; Y549-D747 HydrophobicContact CE1-CB 3.66Å; Y549-D747 HydrophobicContact CE2-CB 3.56Å; Y549-D747 VanDerWaalsContact OH-CB 3.29Å; Y549-D747 WeakPolarHBondContact OH-CB 3.41Å; Y549-D747 PolarHBondContact OH-N 2.96Å
550A42.8Very low35.1Very low17 Ų1765.1 Ų65.114%0.1444%0.444CS..BIsolated β-bridgetrans-103.1128.516800000112.1F725 V726A550-F725 VanDerWaalsContact O-CD2 3.26Å; A550-F725 WeakPolarHBondContact O-CD2 3.5Å; A550-V726 HydrophobicContact CB-CB 3.92Å; A550-V726 PolarHBondContact N-O 3.34Å
551V35.8Very low35.7Very low98 Ų9868.4 Ų68.459%0.59446%0.462SS*.PPolyproline II helixtrans-89.8123.1177.4-176.60000110.7I638V551-I638 HydrophobicContact CG2-CD1 3.67Å; V551-I638 HydrophobicContact CG2-CG1 3.91Å
552P32.4Very low36.3Very low26 Ų2662.3 Ų62.317%0.16945%0.446CS..PPolyproline II helixtrans-79.7154.5172.329.4-30.5000112.4L554 L723 N724P552-L554 HydrophobicContact CG-CD1 4.38Å; P552-L723 WeakPolarHBondContact CG-O 3.25Å; P552-N724 HydrophobicContact CB-CB 3.66Å; P552-N724 WeakPolarHBondContact CB-O 3.03Å; P552-N724 HydrophobicContact CG-CB 3.97Å; P552-N724 WeakPolarHBondContact CG-O 3.37Å
553A31.6Very low37.1Very low103 Ų10364.1 Ų64.185%0.85145%0.453SS*.PPolyproline II helixtrans-71.3133164.800000109.8
554L29.2Very low38.1Very low80 Ų8065.1 Ų65.142%0.41946%0.46SS..  trans-115.5150179.4-78.9115.3000112.2P552 R641P552-L554 HydrophobicContact CG-CD1 4.38Å; L554-R641 VanDerWaalsContact CD1-NH1 3.35Å
555P28.4Very low39.6Very low109 Ų10970.4 Ų70.471%0.70847%0.466SS*.  trans-67.1153.4173.2-1731000112.7G557P555-G557 PolarHBondContact O-N 2.99Å
556P28.7Very low41.8Very low110 Ų11073.6 Ų73.671%0.71448%0.482SS*.THydrogen-bonded Turntrans-70.4122.4170.529.6-33.3000110.6
557G31.2Very low44.1Very low67 Ų6774 Ų7469%0.69148%0.479SS*.THydrogen-bonded Turntrans153.7-16.8169.200000117.7P555 V559P555-G557 PolarHBondContact O-N 2.99Å; G557-V559 PolarHBondContact O-N 3.34Å
558A30.1Very low46.4Very low95 Ų9573 Ų7379%0.78547%0.473SS*.  trans-7486-178.300000112.5
559V37.1Very low48.5Very low151 Ų15174.9 Ų74.992%0.91549%0.486SS*.  trans-71.4125.1173.7-179.50000109.9G557G557-V559 PolarHBondContact O-N 3.34Å
560G37.4Very low50.7Low62 Ų6277.6 Ų77.664%0.63950%0.496SS*.SBendtrans164.1-85.117500000113.1
561D42.6Very low53.1Low93 Ų9381.9 Ų81.950%0.49753%0.525SS..  trans-105.1103.4-159.3-71.9-50.3000114.8K643D561-K643 IonicContact OD1-NZ 3.24Å; D561-K643 PolarHBondContact OD1-NZ 3.19Å; D561-K643 WeakPolarHBondContact OD2-CE 3.44Å; D561-K643 IonicContact OD2-NZ 2.7Å; D561-K643 PolarHBondContact OD2-NZ 3.1Å
562G45.1Very low55.8Low48 Ų4880.3 Ų80.350%0.49551%0.508SS..  trans-87.9-178.3154.900000111.7
563P50.8Low58.8Low66 Ų6680.5 Ų80.543%0.42951%0.508SS..SBendtrans-61.5160.7165.529.7-35.5000111R565P563-R565 PolarHBondContact O-N 3.28Å
564P54.6Low61.9Low36 Ų3681.7 Ų81.723%0.23449%0.49CS..  trans-49.9134.7178.4-2836000112.1V566 V653P564-V566 PolarHBondContact O-N 3.38Å; P564-V653 HydrophobicContact CB-CG2 4.19Å; P564-V653 HydrophobicContact CG-CG2 4.07Å
565R62.8Low65.1Low226 Ų22683.1 Ų83.185%0.85349%0.493SS*.SBendtrans-75.4-15.9-174.4-69.3-178.3173.8-169.7-0.9113.3P563P563-R565 PolarHBondContact O-N 3.28Å
566V80.6Confident68.2Low85 Ų8582.7 Ų82.752%0.51548%0.48SS..SBendtrans-135.8140.6-177.8-1680000107.8P564P564-V566 PolarHBondContact O-N 3.38Å
567D88.3Confident71.2Confident33 Ų3382.2 Ų82.218%0.17647%0.468CS..  trans-66.1142.3171.9-97.116.6000110.7V653 C654 V655 Q656D567-V653 CarbonylContact C-O 3.3Å; D567-V653 WeakPolarHBondContact CA-O 3.38Å; D567-C654 WeakPolarHBondContact OD2-CA 3.02Å; D567-V655 WeakPolarHBondContact OD1-CG2 3.42Å; D567-V655 PolarHBondContact OD1-N 3.02Å; D567-V655 PolarHBondContact OD2-N 3.47Å; D567-Q656 HydrophobicContact CB-CG 4.33Å; D567-Q656 PolarHBondContact OD2-N 3.07Å
568F92Very high74Confident3 Ų383.1 Ų83.11%0.01345%0.454CS..  trans-61.4135.6168.2-169.4-84.1000109.2R570 R572 L573 V592 L598 F603 L605 V653 C654 I663F568-R570 PolarHBondContact O-N 3.28Å; F568-R572 HydrophobicContact CE1-CB 4.36Å; F568-L573 HydrophobicContact CD1-CD1 4.18Å; F568-L573 HydrophobicContact CD1-CD2 4.05Å; F568-L573 HydrophobicContact CD1-CG 4Å; F568-L573 HydrophobicContact CE1-CD1 4.43Å; F568-L573 HydrophobicContact CE1-CD2 3.52Å; F568-L573 HydrophobicContact CE1-CG 3.77Å; F568-L573 HydrophobicContact CZ-CD2 4.24Å; F568-V592 HydrophobicContact CZ-CG1 3.87Å; F568-V592 HydrophobicContact CZ-CG2 4.17Å; F568-L598 HydrophobicContact CE1-CD1 4.39Å; F568-L598 HydrophobicContact CE2-CD1 4.12Å; F568-L598 HydrophobicContact CZ-CD1 3.7Å; F568-F603 HydrophobicContact CB-CE1 4.03Å; F568-F603 HydrophobicContact CB-CZ 4.44Å; F568-F603 AromaticContact CD2-CD1 3.77Å; F568-F603 HydrophobicContact CD2-CD1 3.77Å; F568-F603 HydrophobicContact CD2-CE1 4.01Å; F568-F603 HydrophobicContact CD2-CG 4.1Å; F568-F603 HydrophobicContact CE2-CG 4.49Å; F568-F603 HydrophobicContact CG-CE1 4.49Å; F568-L605 HydrophobicContact CE2-CD1 4.31Å; F568-L605 HydrophobicContact CE2-CD2 4.36Å; F568-V653 WeakPolarHBondContact CB-O 3.34Å; F568-V653 PolarHBondContact N-O 3.08Å; F568-C654 PolarHBondContact O-SG 3.48Å; F568-I663 HydrophobicContact CB-CD1 3.88Å; F568-I663 HydrophobicContact CD1-CD1 4.41Å; F568-I663 HydrophobicContact CG-CD1 4.13Å
569P92Very high76.5Confident43 Ų4381.7 Ų81.728%0.27943%0.432SS..  trans-67.397.7-177.326.2-34.5000111S571 R572 L598P569-S571 PolarHBondContact O-N 3.4Å; P569-R572 HydrophobicContact CB-CG 4.05Å; P569-R572 HydrophobicContact CG-CB 4.29Å; P569-R572 HydrophobicContact CG-CG 3.82Å; P569-R572 WeakPolarHBondContact O-CB 3.23Å; P569-R572 PolarHBondContact O-N 2.83Å; P569-L598 HydrophobicContact CG-CD1 4.1Å; P569-L598 HydrophobicContact CG-CD2 3.78Å
570R92.1Very high78.5Confident78 Ų7875.3 Ų75.329%0.29440%0.397SS..G310 helixtrans-49.7-35-176.6-170.9-171.4-64.1-82.15.7113.5F568 R572 L573 D657 P659 C661F568-R570 PolarHBondContact O-N 3.28Å; R570-R572 PolarHBondContact O-N 2.93Å; R570-L573 WeakPolarHBondContact O-CB 3.3Å; R570-L573 PolarHBondContact O-N 3.07Å; R570-L573 VanDerWaalsContact O-N 3.1Å; R570-D657 PolarHBondContact NH2-O 3.15Å; R570-P659 VanDerWaalsContact CZ-O 3.23Å; R570-P659 PolarHBondContact NH1-O 3.36Å; R570-P659 PolarHBondContact NH2-O 3.09Å; R570-C661 PolarHBondContact NH1-SG 2.94Å
571S92.1Very high80.3Confident108 Ų10877 Ų7776%0.75539%0.389SS*.G310 helixtrans-66.4-12.4177.352.50000115.1P569P569-S571 PolarHBondContact O-N 3.4Å
572R93.1Very high81.5Confident64 Ų6473.2 Ų73.224%0.24237%0.372CS..G310 helixtrans-89.5-6.6172.4-61.7-65.6-161.496.5-4.9113.3F568 P569 R570 R574 V592 D593 S594 D597 L598F568-R572 HydrophobicContact CE1-CB 4.36Å; P569-R572 HydrophobicContact CB-CG 4.05Å; P569-R572 HydrophobicContact CG-CB 4.29Å; P569-R572 HydrophobicContact CG-CG 3.82Å; P569-R572 WeakPolarHBondContact O-CB 3.23Å; P569-R572 PolarHBondContact O-N 2.83Å; R570-R572 PolarHBondContact O-N 2.93Å; R572-R574 PolarHBondContact O-N 3.17Å; R572-V592 WeakPolarHBondContact O-CA 3.32Å; R572-D593 WeakPolarHBondContact CD-O 3.13Å; R572-D593 PolarHBondContact NH1-O 2.88Å; R572-D593 PolarHBondContact O-N 3.36Å; R572-S594 PolarHBondContact NH1-O 2.77Å; R572-D597 IonicContact CZ-OD2 2.76Å; R572-D597 IonicContact NH1-OD2 2.76Å; R572-D597 PolarHBondContact NH1-OD2 2.83Å; R572-D597 VanDerWaalsContact NH1-OD2 3.13Å; R572-D597 IonicContact NH2-OD2 2.78Å; R572-D597 PolarHBondContact NH2-OD2 3.47Å; R572-L598 HydrophobicContact CB-CD1 4.25Å; R572-L598 HydrophobicContact CG-CD1 4.19Å
573L95.3Very high82.4Confident31 Ų3177.3 Ų77.316%0.16238%0.378CS..EExtended strand (participates in β ladder)trans-89.8100.5179-64174.2000110.6F568 R570 C590 V592 V615 V617 I663F568-L573 HydrophobicContact CD1-CD1 4.18Å; F568-L573 HydrophobicContact CD1-CD2 4.05Å; F568-L573 HydrophobicContact CD1-CG 4Å; F568-L573 HydrophobicContact CE1-CD1 4.43Å; F568-L573 HydrophobicContact CE1-CD2 3.52Å; F568-L573 HydrophobicContact CE1-CG 3.77Å; F568-L573 HydrophobicContact CZ-CD2 4.24Å; R570-L573 WeakPolarHBondContact O-CB 3.3Å; R570-L573 PolarHBondContact O-N 3.07Å; R570-L573 VanDerWaalsContact O-N 3.1Å; L573-C590 HydrophobicContact CB-CB 4.4Å; L573-C590 HydrophobicContact CD2-CB 4.33Å; L573-V592 HydrophobicContact CD2-CG2 4.31Å; L573-V615 HydrophobicContact CD2-CG2 4.05Å; L573-V617 HydrophobicContact CD1-CG1 4.42Å; L573-V617 HydrophobicContact CD1-CG2 4.37Å; L573-V617 HydrophobicContact CD2-CG2 4.27Å; L573-I663 HydrophobicContact CD1-CD1 4.34Å; L573-I663 HydrophobicContact CD1-CG1 4.07Å; L573-I663 HydrophobicContact CD2-CG1 4.32Å
574R96Very high83.3Confident127 Ų12776.5 Ų76.548%0.47937%0.367SS..EExtended strand (participates in β ladder)trans-90.3104.3177.5-179.9-176.4-62.6-90.3-7.6110.1R572 C590 E591 D593R572-R574 PolarHBondContact O-N 3.17Å; R574-C590 CarbonylContact O-C 3.6Å; R574-C590 VanDerWaalsContact O-CA 3.28Å; R574-C590 WeakPolarHBondContact O-CA 3.42Å; R574-E591 HydrophobicContact CB-CB 4.39Å; R574-E591 WeakPolarHBondContact CB-O 3.45Å; R574-E591 PolarHBondContact N-O 2.94Å; R574-E591 PolarHBondContact O-N 2.9Å; R574-D593 IonicContact CZ-OD1 3.64Å; R574-D593 IonicContact CZ-OD2 3.93Å; R574-D593 IonicContact NE-OD1 3.73Å; R574-D593 PolarHBondContact NE-OD1 3.42Å; R574-D593 IonicContact NE-OD2 2.73Å; R574-D593 VanDerWaalsContact NH2-CG 3.33Å; R574-D593 IonicContact NH2-OD1 3.75Å; R574-D593 PolarHBondContact NH2-OD1 3.47Å; R574-D593 VanDerWaalsContact NH2-OD1 3.16Å; R574-D593 IonicContact NH2-OD2 2.72Å; R574-D593 PolarHBondContact NH2-OD2 2.86Å
575F96.3Very high84.5Confident110 Ų11075.4 Ų75.448%0.48236%0.363SS..EExtended strand (participates in β ladder)trans-51.7139.5174.4176.2-95.5000112.4E577 H588F575-E577 VanDerWaalsContact CE2-C 3.46Å; F575-E577 VanDerWaalsContact CE2-O 3.32Å; F575-E577 WeakPolarHBondContact CE2-O 3.35Å; F575-E577 VanDerWaalsContact CZ-C 3.46Å; F575-E577 VanDerWaalsContact CZ-CA 3.48Å; F575-H588 HydrophobicContact CD2-CB 3.84Å; F575-H588 AromaticContact CD2-CE1 4Å; F575-H588 AromaticContact CD2-CG 3.63Å; F575-H588 AromaticContact CD2-ND1 3.35Å; F575-H588 VanDerWaalsContact CD2-ND1 3.35Å; F575-H588 WeakPolarHBondContact CD2-ND1 3.39Å; F575-H588 HydrophobicContact CE2-CB 3.95Å; F575-H588 AromaticContact CE2-CD2 3.85Å; F575-H588 AromaticContact CE2-CE1 3.84Å; F575-H588 AromaticContact CE2-CG 3.52Å; F575-H588 AromaticContact CE2-ND1 3.52Å
576K95.1Very high85.5Confident101 Ų10167 Ų6744%0.43933%0.333SS..EExtended strand (participates in β ladder)trans-115.3-60172.1-64.5-70-176.2169.80111L589 E591K576-L589 HydrophobicContact CB-CB 4.27Å; K576-L589 HydrophobicContact CB-CD2 4.29Å; K576-L589 HydrophobicContact CB-CG 4.13Å; K576-L589 WeakPolarHBondContact CB-O 3.49Å; K576-L589 HydrophobicContact CG-CG 4.41Å; K576-L589 PolarHBondContact N-O 2.91Å; K576-E591 VanDerWaalsContact CE-CB 3.44Å; K576-E591 WeakPolarHBondContact CE-OE2 3.29Å; K576-E591 IonicContact NZ-OE2 2.7Å; K576-E591 PolarHBondContact NZ-OE2 2.73Å
577E91.2Very high85.9Confident99 Ų9963.1 Ų63.146%0.46331%0.31SS..EExtended strand (participates in β ladder)trans-157.1168.8-173.859.6-178.3-175.400111.2F575 H588 L589F575-E577 VanDerWaalsContact CE2-C 3.46Å; F575-E577 VanDerWaalsContact CE2-O 3.32Å; F575-E577 WeakPolarHBondContact CE2-O 3.35Å; F575-E577 VanDerWaalsContact CZ-C 3.46Å; F575-E577 VanDerWaalsContact CZ-CA 3.48Å; E577-H588 CarbonylContact O-C 3.54Å; E577-H588 WeakPolarHBondContact O-CA 3.23Å; E577-L589 HydrophobicContact CG-CB 3.74Å; E577-L589 HydrophobicContact CG-CD2 3.96Å; E577-L589 HydrophobicContact CG-CG 4.44Å; E577-L589 PolarHBondContact O-N 2.77Å; E577-L589 WeakPolarHBondContact OE1-CD2 3.38Å
578K89Confident86.1Confident87 Ų8763 Ų6338%0.37831%0.308SS..EExtended strand (participates in β ladder)trans-101.3110.9179177.9172.4168.5178.60109.2E581 E586 V587K578-E581 IonicContact NZ-OE2 3.51Å; K578-E581 PolarHBondContact NZ-OE2 3.15Å; K578-E586 VanDerWaalsContact CE-CD 3.45Å; K578-E586 WeakPolarHBondContact CE-OE1 3.43Å; K578-E586 VanDerWaalsContact NZ-CD 3.25Å; K578-E586 IonicContact NZ-OE1 3.67Å; K578-E586 PolarHBondContact NZ-OE1 3.08Å; K578-E586 IonicContact NZ-OE2 3.61Å; K578-V587 CarbonylContact C-O 3.57Å
579L83.8Confident86.2Confident64 Ų6463.3 Ų63.334%0.33531%0.31SS..EExtended strand (participates in β ladder)trans-76.4-22.3-179.6-63.7174.7000112.6V587 L589 A616 Y666L579-V587 HydrophobicContact CB-CB 4.49Å; L579-V587 HydrophobicContact CB-CG1 4.19Å; L579-V587 HydrophobicContact CD1-CG1 4.19Å; L579-V587 PolarHBondContact N-O 2.92Å; L579-L589 HydrophobicContact CD1-CB 3.98Å; L579-L589 HydrophobicContact CD2-CB 4.12Å; L579-L589 HydrophobicContact CG-CB 3.93Å; L579-A616 HydrophobicContact CD1-CB 4.26Å; L579-Y666 HydrophobicContact CD1-CD2 4.04Å; L579-Y666 HydrophobicContact CD1-CE2 3.79Å; L579-Y666 HydrophobicContact CD2-CE2 4.09Å
580G77.5Confident86.3Confident18 Ų1861.6 Ų61.619%0.18630%0.299CS..EExtended strand (participates in β ladder)trans176.7177173.200000115V587 M750G580-V587 PolarHBondContact N-O 3.43Å; G580-V587 PolarHBondContact O-N 3.31Å; G580-M750 VanDerWaalsContact CA-SD 3.56Å
581E75.6Confident86.5Confident98 Ų9860 Ų6046%0.45829%0.294SS..EExtended strand (participates in β ladder)trans-137129.5-180-172.2170.7164.700110.7K578 E586 N753K578-E581 IonicContact NZ-OE2 3.51Å; K578-E581 PolarHBondContact NZ-OE2 3.15Å; E581-E586 HydrophobicContact CG-CG 4.48Å; E581-N753 PolarHBondContact O-ND2 3.04Å
582G67.8Low86.6Confident13 Ų1355 Ų5513%0.13426%0.259CS..EExtended strand (participates in β ladder)trans-114.3169.4171.200000111.2F584 G585G582-F584 PolarHBondContact O-N 3.39Å; G582-G585 CarbonylContact C-O 3.58Å; G582-G585 PolarHBondContact N-O 3.34Å; G582-G585 PolarHBondContact O-N 2.75Å
583Q65.5Low86.5Confident133 Ų13354 Ų5462%0.62126%0.259SS*.THydrogen-bonded Turntrans-50.5-31.5-173.3-170.2178.77.200115R621Q583-R621 PolarHBondContact O-NH2 3.05Å
584F68.1Low86.1Confident49 Ų4955.9 Ų55.922%0.21528%0.275CS..THydrogen-bonded Turntrans-123.62.9-174.1-50.7-68.9000114.6G582 L620 R621 A628G582-F584 PolarHBondContact O-N 3.39Å; F584-L620 HydrophobicContact CB-CD1 4.27Å; F584-L620 WeakPolarHBondContact O-CD1 3.21Å; F584-R621 PolarHBondContact O-N 3.1Å; F584-A628 HydrophobicContact CB-CB 3.83Å; F584-A628 HydrophobicContact CD1-CB 3.78Å; F584-A628 HydrophobicContact CD2-CB 4.08Å; F584-A628 HydrophobicContact CE1-CB 4.36Å; F584-A628 HydrophobicContact CG-CB 3.61Å
585G79.6Confident85.7Confident14 Ų1450.3 Ų50.314%0.14426%0.255CS..EExtended strand (participates in β ladder)trans-170.3167.2-166.200000113.7G582 I619G582-G585 CarbonylContact C-O 3.58Å; G582-G585 PolarHBondContact N-O 3.34Å; G582-G585 PolarHBondContact O-N 2.75Å; G585-I619 CarbonylContact C-O 3.54Å; G585-I619 WeakPolarHBondContact CA-O 3.49Å
586E85.4Confident85.1Confident49 Ų4950.1 Ų50.123%0.22926%0.255CS..EExtended strand (participates in β ladder)trans-118.8162177.1-55.3-168.5160.200110.1K578 E581 H588 K618 I619K578-E586 VanDerWaalsContact CE-CD 3.45Å; K578-E586 WeakPolarHBondContact CE-OE1 3.43Å; K578-E586 VanDerWaalsContact NZ-CD 3.25Å; K578-E586 IonicContact NZ-OE1 3.67Å; K578-E586 PolarHBondContact NZ-OE1 3.08Å; K578-E586 IonicContact NZ-OE2 3.61Å; E581-E586 HydrophobicContact CG-CG 4.48Å; E586-H588 IonicContact OE2-CD2 2.73Å; E586-H588 IonicContact OE2-CE1 3.43Å; E586-H588 IonicContact OE2-NE2 3.51Å; E586-H588 PolarHBondContact OE2-NE2 2.8Å; E586-K618 CarbonylContact O-C 3.54Å; E586-K618 WeakPolarHBondContact O-CA 3.36Å; E586-I619 PolarHBondContact N-O 3.18Å; E586-I619 PolarHBondContact O-N 3.21Å
587V88.3Confident84.6Confident3 Ų350.4 Ų50.42%0.01826%0.262CS..EExtended strand (participates in β ladder)trans-118.9128162.5178.80000108.9K578 L579 G580 A616 V617 K618 F748 M750K578-V587 CarbonylContact C-O 3.57Å; L579-V587 HydrophobicContact CB-CB 4.49Å; L579-V587 HydrophobicContact CB-CG1 4.19Å; L579-V587 HydrophobicContact CD1-CG1 4.19Å; L579-V587 PolarHBondContact N-O 2.92Å; G580-V587 PolarHBondContact N-O 3.43Å; G580-V587 PolarHBondContact O-N 3.31Å; V587-A616 HydrophobicContact CG1-CB 4.25Å; V587-V617 WeakPolarHBondContact CA-O 3.49Å; V587-K618 HydrophobicContact CG2-CB 4.01Å; V587-K618 HydrophobicContact CG2-CG 3.83Å; V587-F748 HydrophobicContact CG2-CD1 3.98Å; V587-M750 HydrophobicContact CB-CE 3.81Å; V587-M750 HydrophobicContact CB-SD 3.53Å; V587-M750 VanDerWaalsContact CB-SD 3.53Å; V587-M750 HydrophobicContact CG1-CE 4.34Å; V587-M750 HydrophobicContact CG2-CE 3.66Å; V587-M750 HydrophobicContact CG2-CG 4.29Å; V587-M750 HydrophobicContact CG2-SD 3.31Å; V587-M750 WeakPolarHBondContact CG2-SD 3.47Å
588H91.6Very high84.2Confident31 Ų3146.7 Ų46.714%0.14425%0.245CC..EExtended strand (participates in β ladder)trans-110.2146.9178.6-64.9178.1000110.7F575 E577 E586 V617 I619F575-H588 HydrophobicContact CD2-CB 3.84Å; F575-H588 AromaticContact CD2-CE1 4Å; F575-H588 AromaticContact CD2-CG 3.63Å; F575-H588 AromaticContact CD2-ND1 3.35Å; F575-H588 VanDerWaalsContact CD2-ND1 3.35Å; F575-H588 WeakPolarHBondContact CD2-ND1 3.39Å; F575-H588 HydrophobicContact CE2-CB 3.95Å; F575-H588 AromaticContact CE2-CD2 3.85Å; F575-H588 AromaticContact CE2-CE1 3.84Å; F575-H588 AromaticContact CE2-CG 3.52Å; F575-H588 AromaticContact CE2-ND1 3.52Å; E577-H588 CarbonylContact O-C 3.54Å; E577-H588 WeakPolarHBondContact O-CA 3.23Å; E586-H588 IonicContact OE2-CD2 2.73Å; E586-H588 IonicContact OE2-CE1 3.43Å; E586-H588 IonicContact OE2-NE2 3.51Å; E586-H588 PolarHBondContact OE2-NE2 2.8Å; H588-V617 PolarHBondContact N-O 3.11Å; H588-V617 PolarHBondContact O-N 2.82Å; H588-I619 VanDerWaalsContact ND1-CD1 3.35Å; H588-I619 WeakPolarHBondContact ND1-CD1 3.44Å
589L94.1Very high83.9Confident10 Ų1046.4 Ų46.45%0.05225%0.251CS..EExtended strand (participates in β ladder)trans-83.1126.9160-178.258.2000108K576 E577 L579 L614 Y666K576-L589 HydrophobicContact CB-CB 4.27Å; K576-L589 HydrophobicContact CB-CD2 4.29Å; K576-L589 HydrophobicContact CB-CG 4.13Å; K576-L589 WeakPolarHBondContact CB-O 3.49Å; K576-L589 HydrophobicContact CG-CG 4.41Å; K576-L589 PolarHBondContact N-O 2.91Å; E577-L589 HydrophobicContact CG-CB 3.74Å; E577-L589 HydrophobicContact CG-CD2 3.96Å; E577-L589 HydrophobicContact CG-CG 4.44Å; E577-L589 PolarHBondContact O-N 2.77Å; E577-L589 WeakPolarHBondContact OE1-CD2 3.38Å; L579-L589 HydrophobicContact CD1-CB 3.98Å; L579-L589 HydrophobicContact CD2-CB 4.12Å; L579-L589 HydrophobicContact CG-CB 3.93Å; L589-L614 HydrophobicContact CD1-CB 4.07Å; L589-L614 HydrophobicContact CD1-CD2 4.32Å; L589-L614 HydrophobicContact CG-CD2 4.5Å; L589-Y666 HydrophobicContact CD1-CD1 3.89Å; L589-Y666 HydrophobicContact CD1-CD2 3.56Å; L589-Y666 HydrophobicContact CD1-CE1 4.05Å; L589-Y666 HydrophobicContact CD1-CE2 3.74Å; L589-Y666 HydrophobicContact CD1-CG 3.65Å; L589-Y666 HydrophobicContact CD2-CE1 4.45Å
590C95.8Very high83.7Confident6 Ų645.8 Ų45.84%0.04125%0.251CS..EExtended strand (participates in β ladder)trans-124.7144.9174.3-67.50000110.9L573 R574 L614 V615 V617L573-C590 HydrophobicContact CB-CB 4.4Å; L573-C590 HydrophobicContact CD2-CB 4.33Å; R574-C590 CarbonylContact O-C 3.6Å; R574-C590 VanDerWaalsContact O-CA 3.28Å; R574-C590 WeakPolarHBondContact O-CA 3.42Å; C590-L614 WeakPolarHBondContact O-CA 3.29Å; C590-V615 HydrophobicContact CB-CG2 4.03Å; C590-V615 PolarHBondContact N-O 3.48Å; C590-V615 PolarHBondContact O-N 2.94Å; C590-V617 HydrophobicContact CB-CG2 3.86Å
591E95.3Very high83.1Confident44 Ų4453.5 Ų53.521%0.20629%0.288CS..EExtended strand (participates in β ladder)trans-90.5141.3160.8179176.4-166.100109R574 K576 P612 L613 L614R574-E591 HydrophobicContact CB-CB 4.39Å; R574-E591 WeakPolarHBondContact CB-O 3.45Å; R574-E591 PolarHBondContact N-O 2.94Å; R574-E591 PolarHBondContact O-N 2.9Å; K576-E591 VanDerWaalsContact CE-CB 3.44Å; K576-E591 WeakPolarHBondContact CE-OE2 3.29Å; K576-E591 IonicContact NZ-OE2 2.7Å; K576-E591 PolarHBondContact NZ-OE2 2.73Å; E591-P612 HydrophobicContact CG-CB 4.15Å; E591-P612 VanDerWaalsContact OE1-CB 3.25Å; E591-P612 WeakPolarHBondContact OE1-CB 3.45Å; E591-L613 CarbonylContact C-O 3.57Å; E591-L613 WeakPolarHBondContact CA-O 3.44Å; E591-L614 HydrophobicContact CB-CD2 4.22Å
592V94.4Very high83Confident3 Ų352 Ų522%0.01828%0.283CS..EExtended strand (participates in β ladder)trans-92.7116.7174.2-178.60000109.7F568 R572 L573 P595 L598 L613 V615F568-V592 HydrophobicContact CZ-CG1 3.87Å; F568-V592 HydrophobicContact CZ-CG2 4.17Å; R572-V592 WeakPolarHBondContact O-CA 3.32Å; L573-V592 HydrophobicContact CD2-CG2 4.31Å; V592-P595 HydrophobicContact CB-CB 4.18Å; V592-P595 HydrophobicContact CG1-CB 3.85Å; V592-P595 WeakPolarHBondContact O-CD 3.46Å; V592-L598 HydrophobicContact CG1-CD1 3.74Å; V592-L613 HydrophobicContact CB-CB 4.26Å; V592-L613 HydrophobicContact CB-CD2 4.03Å; V592-L613 HydrophobicContact CB-CG 4.34Å; V592-L613 HydrophobicContact CG1-CD2 4.48Å; V592-L613 HydrophobicContact CG2-CD2 3.95Å; V592-L613 HydrophobicContact CG2-CG 4.2Å; V592-L613 PolarHBondContact N-O 2.84Å; V592-V615 HydrophobicContact CG2-CG1 3.94Å; V592-V615 HydrophobicContact CG2-CG2 3.8Å
593D91.6Very high83.7Confident45 Ų4552.2 Ų52.224%0.24128%0.28CS..SBendtrans-68.1132.3175.5-81.4-1.3000111.4R572 R574R572-D593 WeakPolarHBondContact CD-O 3.13Å; R572-D593 PolarHBondContact NH1-O 2.88Å; R572-D593 PolarHBondContact O-N 3.36Å; R574-D593 IonicContact CZ-OD1 3.64Å; R574-D593 IonicContact CZ-OD2 3.93Å; R574-D593 IonicContact NE-OD1 3.73Å; R574-D593 PolarHBondContact NE-OD1 3.42Å; R574-D593 IonicContact NE-OD2 2.73Å; R574-D593 VanDerWaalsContact NH2-CG 3.33Å; R574-D593 IonicContact NH2-OD1 3.75Å; R574-D593 PolarHBondContact NH2-OD1 3.47Å; R574-D593 VanDerWaalsContact NH2-OD1 3.16Å; R574-D593 IonicContact NH2-OD2 2.72Å; R574-D593 PolarHBondContact NH2-OD2 2.86Å
594S87.1Confident84.5Confident69 Ų6948.5 Ų48.548%0.48327%0.267SS..SBendtrans40.960.7-178.5-61.30000113.8R572 Q596 D597R572-S594 PolarHBondContact NH1-O 2.77Å; S594-Q596 PolarHBondContact O-N 2.82Å; S594-Q596 VanDerWaalsContact O-N 3.16Å; S594-D597 VanDerWaalsContact CB-OD2 3.31Å; S594-D597 WeakPolarHBondContact CB-OD2 3.32Å; S594-D597 PolarHBondContact O-N 2.79Å
595P86Confident85.2Confident10 Ų1046.7 Ų46.77%0.06526%0.26CS..G310 helixtrans-69.1-17.4-168.229.7-35.9000113.4V592 D597 L598 V599 V607 L613V592-P595 HydrophobicContact CB-CB 4.18Å; V592-P595 HydrophobicContact CG1-CB 3.85Å; V592-P595 WeakPolarHBondContact O-CD 3.46Å; P595-D597 PolarHBondContact O-N 2.84Å; P595-L598 PolarHBondContact O-N 3.38Å; P595-L598 VanDerWaalsContact O-N 3.16Å; P595-V599 WeakPolarHBondContact O-CG2 3.44Å; P595-V607 HydrophobicContact CB-CG1 4.45Å; P595-V607 HydrophobicContact CB-CG2 3.91Å; P595-V607 HydrophobicContact CG-CG1 3.93Å; P595-V607 HydrophobicContact CG-CG2 4.29Å; P595-L613 HydrophobicContact CB-CB 4.02Å; P595-L613 HydrophobicContact CB-CD2 3.72Å; P595-L613 HydrophobicContact CG-CB 3.98Å
596Q84Confident85.4Confident106 Ų10651.3 Ų51.350%0.49528%0.281SS..G310 helixtrans-61.1-32.4176.5-62.376.916.400112.1S594 L598 V607S594-Q596 PolarHBondContact O-N 2.82Å; S594-Q596 VanDerWaalsContact O-N 3.16Å; Q596-L598 PolarHBondContact O-N 3.49Å; Q596-V607 HydrophobicContact CG-CG1 4.09Å
597D84.3Confident85.3Confident107 Ų10750.7 Ų50.757%0.57228%0.281SS*.G310 helixtrans-68.1-19.9178.9-50.2-25.8000112.9R572 S594 P595R572-D597 IonicContact CZ-OD2 2.76Å; R572-D597 IonicContact NH1-OD2 2.76Å; R572-D597 PolarHBondContact NH1-OD2 2.83Å; R572-D597 VanDerWaalsContact NH1-OD2 3.13Å; R572-D597 IonicContact NH2-OD2 2.78Å; R572-D597 PolarHBondContact NH2-OD2 3.47Å; S594-D597 VanDerWaalsContact CB-OD2 3.31Å; S594-D597 WeakPolarHBondContact CB-OD2 3.32Å; S594-D597 PolarHBondContact O-N 2.79Å; P595-D597 PolarHBondContact O-N 2.84Å
598L83Confident85Confident21 Ų2156.4 Ų56.411%0.1130%0.302CS..G310 helixtrans-102.8-14.8-169-54.5-178.8000112.9F568 P569 R572 V592 P595 Q596 S600 L605F568-L598 HydrophobicContact CE1-CD1 4.39Å; F568-L598 HydrophobicContact CE2-CD1 4.12Å; F568-L598 HydrophobicContact CZ-CD1 3.7Å; P569-L598 HydrophobicContact CG-CD1 4.1Å; P569-L598 HydrophobicContact CG-CD2 3.78Å; R572-L598 HydrophobicContact CB-CD1 4.25Å; R572-L598 HydrophobicContact CG-CD1 4.19Å; V592-L598 HydrophobicContact CG1-CD1 3.74Å; P595-L598 PolarHBondContact O-N 3.38Å; P595-L598 VanDerWaalsContact O-N 3.16Å; Q596-L598 PolarHBondContact O-N 3.49Å; L598-S600 WeakPolarHBondContact O-CB 3.32Å; L598-S600 PolarHBondContact O-N 2.71Å; L598-S600 PolarHBondContact O-OG 3.16Å; L598-L605 HydrophobicContact CB-CD1 3.8Å; L598-L605 HydrophobicContact CD1-CD1 4.48Å
599V83.5Confident84.3Confident82 Ų8264.5 Ų64.550%0.49734%0.337SS..  trans-61.4110.7-177.7-174.70000109.8P595 V607P595-V599 WeakPolarHBondContact O-CG2 3.44Å; V599-V607 HydrophobicContact CG2-CB 4.36Å; V599-V607 HydrophobicContact CG2-CG2 3.58Å
600S78.6Confident83.4Confident50 Ų5067.7 Ų67.735%0.3537%0.372SS..SBendtrans-155.4176.1-168.956.40000110.9L598 D602 F603L598-S600 WeakPolarHBondContact O-CB 3.32Å; L598-S600 PolarHBondContact O-N 2.71Å; L598-S600 PolarHBondContact O-OG 3.16Å; S600-D602 VanDerWaalsContact C-N 3.27Å; S600-F603 PolarHBondContact N-O 3.38Å; S600-F603 CarbonylContact O-C 3.53Å; S600-F603 PolarHBondContact OG-N 3.27Å; S600-F603 VanDerWaalsContact OG-N 3.09Å
601L66.1Low82.8Confident181 Ų18173.2 Ų73.295%0.94840%0.397SS*.SBendtrans-67-29.7172-74169000112.2
602D72.9Confident82.5Confident66 Ų6674.8 Ų74.835%0.35341%0.411SS..SBendtrans-79.9-30.2177.2-63-86.5000112.8S600S600-D602 VanDerWaalsContact C-N 3.27Å
603F81.9Confident82.3Confident18 Ų1875.6 Ų75.68%0.07942%0.416CS..  trans-125.692.9178.5-47.1-54.9000111.7F568 S600 L605F568-F603 HydrophobicContact CB-CE1 4.03Å; F568-F603 HydrophobicContact CB-CZ 4.44Å; F568-F603 AromaticContact CD2-CD1 3.77Å; F568-F603 HydrophobicContact CD2-CD1 3.77Å; F568-F603 HydrophobicContact CD2-CE1 4.01Å; F568-F603 HydrophobicContact CD2-CG 4.1Å; F568-F603 HydrophobicContact CE2-CG 4.49Å; F568-F603 HydrophobicContact CG-CE1 4.49Å; S600-F603 PolarHBondContact N-O 3.38Å; S600-F603 CarbonylContact O-C 3.53Å; S600-F603 PolarHBondContact OG-N 3.27Å; S600-F603 VanDerWaalsContact OG-N 3.09Å; F603-L605 HydrophobicContact CB-CD2 4.45Å; F603-L605 HydrophobicContact CB-CG 4.15Å; F603-L605 PolarHBondContact O-N 3.47Å
604P82.6Confident82.4Confident55 Ų5576.4 Ų76.436%0.35742%0.419SS..  trans-82.158.2-173.934.5-37.6000112.9R649P604-R649 PolarHBondContact O-NH1 3.02Å; P604-R649 PolarHBondContact O-NH2 2.9Å
605L84Confident82.7Confident10 Ų1073.1 Ų73.15%0.05240%0.397CS..  trans-73.6133.2-174.4-52.7-179.4000112.6F568 L598 F603 V607 L613 L651F568-L605 HydrophobicContact CE2-CD1 4.31Å; F568-L605 HydrophobicContact CE2-CD2 4.36Å; L598-L605 HydrophobicContact CB-CD1 3.8Å; L598-L605 HydrophobicContact CD1-CD1 4.48Å; F603-L605 HydrophobicContact CB-CD2 4.45Å; F603-L605 HydrophobicContact CB-CG 4.15Å; F603-L605 PolarHBondContact O-N 3.47Å; L605-V607 HydrophobicContact CB-CG2 3.95Å; L605-V607 PolarHBondContact O-N 3.21Å; L605-L613 HydrophobicContact CB-CD2 3.87Å; L605-L613 HydrophobicContact CD1-CD2 3.85Å; L605-L613 HydrophobicContact CD2-CD2 4.18Å; L605-L613 HydrophobicContact CG-CD2 4.17Å; L605-L651 HydrophobicContact CD2-CB 4.05Å; L605-L651 HydrophobicContact CD2-CD1 4.1Å
606N82.7Confident83.1Confident111 Ų11173 Ų7359%0.59440%0.397SS*.  trans-89.776.1178.4-171.210.7000111.5R608N606-R608 PolarHBondContact O-N 2.95Å
607V84.1Confident83.5Confident37 Ų3768 Ų6822%0.22437%0.373CS..  trans-83.7104.2-171.6-174.50000112.1P595 Q596 V599 L605 L613P595-V607 HydrophobicContact CB-CG1 4.45Å; P595-V607 HydrophobicContact CB-CG2 3.91Å; P595-V607 HydrophobicContact CG-CG1 3.93Å; P595-V607 HydrophobicContact CG-CG2 4.29Å; Q596-V607 HydrophobicContact CG-CG1 4.09Å; V599-V607 HydrophobicContact CG2-CB 4.36Å; V599-V607 HydrophobicContact CG2-CG2 3.58Å; L605-V607 HydrophobicContact CB-CG2 3.95Å; L605-V607 PolarHBondContact O-N 3.21Å; V607-L613 HydrophobicContact CG2-CD2 4.27Å
608R82Confident83.7Confident122 Ų12264 Ų6446%0.4635%0.351SS..  trans-75.2130.2168.1-69.4-177.1-179164.34.8110.8N606 G610 H611 E739N606-R608 PolarHBondContact O-N 2.95Å; R608-G610 PolarHBondContact O-N 3.05Å; R608-H611 HydrophobicContact CB-CB 4.07Å; R608-H611 PolarHBondContact O-N 2.84Å; R608-E739 IonicContact CZ-OE1 2.7Å; R608-E739 VanDerWaalsContact CZ-OE1 3.24Å; R608-E739 IonicContact CZ-OE2 2.73Å; R608-E739 IonicContact NH1-OE1 3.61Å; R608-E739 PolarHBondContact NH1-OE1 3.25Å; R608-E739 IonicContact NH1-OE2 3.55Å; R608-E739 PolarHBondContact NH1-OE2 3.43Å; R608-E739 VanDerWaalsContact NH2-CD 3.32Å; R608-E739 IonicContact NH2-OE1 2.7Å; R608-E739 PolarHBondContact NH2-OE1 3.04Å; R608-E739 VanDerWaalsContact NH2-OE1 3.14Å; R608-E739 IonicContact NH2-OE2 2.73Å; R608-E739 PolarHBondContact NH2-OE2 3.33Å
609K77.1Confident84.1Confident201 Ų20164.5 Ų64.587%0.87435%0.353SS*.THydrogen-bonded Turntrans-62.7129-178.8-167.6175.3-177.8179.10110.5H611K609-H611 VanDerWaalsContact C-N 3.29Å; K609-H611 PolarHBondContact O-N 3.31Å; K609-H611 PolarHBondContact O-ND1 2.8Å; K609-H611 VanDerWaalsContact O-ND1 3.16Å
610G75.6Confident84.3Confident78 Ų7861.1 Ų61.180%0.80433%0.332SS*.THydrogen-bonded Turntrans75.27.8178.400000115.9R608R608-G610 PolarHBondContact O-N 3.05Å
611H82.7Confident84.6Confident122 Ų12262.2 Ų62.257%0.56533%0.329SS*.SBendtrans-116148.2177.1-68.469000110.4R608 K609R608-H611 HydrophobicContact CB-CB 4.07Å; R608-H611 PolarHBondContact O-N 2.84Å; K609-H611 VanDerWaalsContact C-N 3.29Å; K609-H611 PolarHBondContact O-N 3.31Å; K609-H611 PolarHBondContact O-ND1 2.8Å; K609-H611 VanDerWaalsContact O-ND1 3.16Å
612P87.8Confident85.3Confident77 Ų7758.7 Ų58.750%0.532%0.317SS..  trans-67.4138.617430.3-35.6000110.2E591 L614E591-P612 HydrophobicContact CG-CB 4.15Å; E591-P612 VanDerWaalsContact OE1-CB 3.25Å; E591-P612 WeakPolarHBondContact OE1-CB 3.45Å; P612-L614 PolarHBondContact O-N 3.09Å
613L91Very high85.7Confident20 Ų2061 Ų6111%0.10533%0.329CS..EExtended strand (participates in β ladder)trans-88.2106.1171.7178.266000109.1E591 V592 P595 L605 V607 V615E591-L613 CarbonylContact C-O 3.57Å; E591-L613 WeakPolarHBondContact CA-O 3.44Å; V592-L613 HydrophobicContact CB-CB 4.26Å; V592-L613 HydrophobicContact CB-CD2 4.03Å; V592-L613 HydrophobicContact CB-CG 4.34Å; V592-L613 HydrophobicContact CG1-CD2 4.48Å; V592-L613 HydrophobicContact CG2-CD2 3.95Å; V592-L613 HydrophobicContact CG2-CG 4.2Å; V592-L613 PolarHBondContact N-O 2.84Å; P595-L613 HydrophobicContact CB-CB 4.02Å; P595-L613 HydrophobicContact CB-CD2 3.72Å; P595-L613 HydrophobicContact CG-CB 3.98Å; L605-L613 HydrophobicContact CB-CD2 3.87Å; L605-L613 HydrophobicContact CD1-CD2 3.85Å; L605-L613 HydrophobicContact CD2-CD2 4.18Å; L605-L613 HydrophobicContact CG-CD2 4.17Å; V607-L613 HydrophobicContact CG2-CD2 4.27Å; L613-V615 HydrophobicContact CG-CG1 4.27Å
614L93.5Very high85.5Confident61 Ų6161.1 Ų61.132%0.31933%0.333SS..EExtended strand (participates in β ladder)trans-89137.3173.8-64.3-179.3000111L589 C590 E591 P612 Y666L589-L614 HydrophobicContact CD1-CB 4.07Å; L589-L614 HydrophobicContact CD1-CD2 4.32Å; L589-L614 HydrophobicContact CG-CD2 4.5Å; C590-L614 WeakPolarHBondContact O-CA 3.29Å; E591-L614 HydrophobicContact CB-CD2 4.22Å; P612-L614 PolarHBondContact O-N 3.09Å; L614-Y666 HydrophobicContact CB-CD1 3.84Å; L614-Y666 HydrophobicContact CB-CG 4.28Å; L614-Y666 HydrophobicContact CD1-CD1 4.04Å; L614-Y666 HydrophobicContact CD1-CE1 4.13Å
615V94.3Very high85.3Confident1 Ų162.1 Ų62.11%0.00634%0.339CS..EExtended strand (participates in β ladder)trans-138145.6178.3-63.90000110.7L573 C590 V592 L613 V617 L651 I663 T664L573-V615 HydrophobicContact CD2-CG2 4.05Å; C590-V615 HydrophobicContact CB-CG2 4.03Å; C590-V615 PolarHBondContact N-O 3.48Å; C590-V615 PolarHBondContact O-N 2.94Å; V592-V615 HydrophobicContact CG2-CG1 3.94Å; V592-V615 HydrophobicContact CG2-CG2 3.8Å; L613-V615 HydrophobicContact CG-CG1 4.27Å; V615-V617 HydrophobicContact CG2-CG2 4.03Å; V615-L651 HydrophobicContact CG1-CD1 3.78Å; V615-I663 HydrophobicContact CB-CG2 3.62Å; V615-I663 HydrophobicContact CG1-CG2 3.98Å; V615-I663 HydrophobicContact CG2-CG2 3.68Å; V615-T664 WeakPolarHBondContact CB-O 3.5Å
616A92.7Very high85Confident8 Ų870 Ų707%0.06637%0.372CS..EExtended strand (participates in β ladder)trans-88.3133.1169.600000109.2L579 V587 I663 T664L579-A616 HydrophobicContact CD1-CB 4.26Å; V587-A616 HydrophobicContact CG1-CB 4.25Å; A616-I663 WeakPolarHBondContact O-CA 3.38Å; A616-T664 PolarHBondContact N-O 3.11Å; A616-T664 VanDerWaalsContact N-O 3.11Å; A616-T664 PolarHBondContact O-N 3.41Å
617V92.6Very high84.5Confident1 Ų170.1 Ų70.11%0.00637%0.373CS..EExtended strand (participates in β ladder)trans-122.2107.9-177.6-171.90000109.5L573 V587 H588 C590 V615 I619 C661 M662 I663L573-V617 HydrophobicContact CD1-CG1 4.42Å; L573-V617 HydrophobicContact CD1-CG2 4.37Å; L573-V617 HydrophobicContact CD2-CG2 4.27Å; V587-V617 WeakPolarHBondContact CA-O 3.49Å; H588-V617 PolarHBondContact N-O 3.11Å; H588-V617 PolarHBondContact O-N 2.82Å; C590-V617 HydrophobicContact CB-CG2 3.86Å; V615-V617 HydrophobicContact CG2-CG2 4.03Å; V617-I619 HydrophobicContact CG1-CD1 4.29Å; V617-I619 HydrophobicContact CG1-CG1 3.87Å; V617-C661 HydrophobicContact CG1-CB 3.9Å; V617-M662 CarbonylContact C-O 3.34Å; V617-M662 VanDerWaalsContact CA-O 3.31Å; V617-M662 WeakPolarHBondContact CA-O 3.49Å; V617-I663 HydrophobicContact CG1-CG1 4.36Å; V617-I663 HydrophobicContact CG2-CG1 4.18Å; V617-I663 HydrophobicContact CG2-CG2 4.46Å
618K89.8Confident83.9Confident22 Ų2268.7 Ų68.710%0.09637%0.365CS..EExtended strand (participates in β ladder)trans-79.8123.2171.3-162.6-175.2-160.9-177.70108.3E586 V587 F632 E635 C661 M662 F748E586-K618 CarbonylContact O-C 3.54Å; E586-K618 WeakPolarHBondContact O-CA 3.36Å; V587-K618 HydrophobicContact CG2-CB 4.01Å; V587-K618 HydrophobicContact CG2-CG 3.83Å; K618-F632 HydrophobicContact CB-CE2 4.47Å; K618-F632 HydrophobicContact CD-CE2 4.22Å; K618-F632 HydrophobicContact CG-CE2 4.12Å; K618-F632 WeakPolarHBondContact O-CZ 3.28Å; K618-E635 IonicContact NZ-OE1 2.72Å; K618-E635 PolarHBondContact NZ-OE1 3.02Å; K618-E635 IonicContact NZ-OE2 3.85Å; K618-E635 PolarHBondContact NZ-OE2 2.73Å; K618-C661 CarbonylContact O-C 3.59Å; K618-C661 VanDerWaalsContact O-CA 3.25Å; K618-C661 WeakPolarHBondContact O-CA 3.33Å; K618-M662 HydrophobicContact CB-CB 4.46Å; K618-M662 HydrophobicContact CD-CE 3.73Å; K618-M662 PolarHBondContact N-O 3.03Å; K618-M662 PolarHBondContact O-N 3.48Å; K618-F748 HydrophobicContact CD-CD1 4.29Å; K618-F748 WeakPolarHBondContact CE-O 3.43Å; K618-F748 PolarHBondContact NZ-O 2.87Å
619I90.1Very high83.8Confident32 Ų3266.9 Ų66.916%0.16436%0.358CS..EExtended strand (participates in β ladder)trans-120124.1-174.5-51.1-173.3000109.5G585 E586 H588 V617 P659 L660G585-I619 CarbonylContact C-O 3.54Å; G585-I619 WeakPolarHBondContact CA-O 3.49Å; E586-I619 PolarHBondContact N-O 3.18Å; E586-I619 PolarHBondContact O-N 3.21Å; H588-I619 VanDerWaalsContact ND1-CD1 3.35Å; H588-I619 WeakPolarHBondContact ND1-CD1 3.44Å; V617-I619 HydrophobicContact CG1-CD1 4.29Å; V617-I619 HydrophobicContact CG1-CG1 3.87Å; I619-P659 HydrophobicContact CG2-CB 3.76Å; I619-P659 HydrophobicContact CG2-CG 3.87Å; I619-L660 WeakPolarHBondContact CA-O 3.5Å
620L88.7Confident83.9Confident10 Ų1059.5 Ų59.55%0.05233%0.329CS..EExtended strand (participates in β ladder)trans-76.9132.9170-172.576.4000109.9F584 A624 A628 R629 F632 P659 L660F584-L620 HydrophobicContact CB-CD1 4.27Å; F584-L620 WeakPolarHBondContact O-CD1 3.21Å; L620-A624 HydrophobicContact CD1-CB 3.73Å; L620-A624 HydrophobicContact CD2-CB 4.12Å; L620-A624 HydrophobicContact CG-CB 3.72Å; L620-A628 HydrophobicContact CD1-CB 4.36Å; L620-R629 HydrophobicContact CD2-CB 3.83Å; L620-R629 HydrophobicContact CD2-CG 3.82Å; L620-F632 HydrophobicContact CB-CD2 3.92Å; L620-F632 HydrophobicContact CB-CE2 4.04Å; L620-F632 HydrophobicContact CB-CG 4.24Å; L620-F632 HydrophobicContact CB-CZ 4.47Å; L620-F632 HydrophobicContact CD1-CB 4.23Å; L620-F632 HydrophobicContact CD1-CD2 4.15Å; L620-F632 HydrophobicContact CD1-CG 4.43Å; L620-F632 HydrophobicContact CD2-CB 4.46Å; L620-P659 WeakPolarHBondContact O-CB 3.46Å; L620-L660 HydrophobicContact CB-CB 4.11Å; L620-L660 HydrophobicContact CD2-CB 4.45Å; L620-L660 HydrophobicContact CD2-CD1 3.98Å; L620-L660 HydrophobicContact CD2-CG 4.3Å; L620-L660 PolarHBondContact N-O 2.88Å
621R84.2Confident83.7Confident74 Ų7458 Ų5828%0.27930%0.302SS..  trans-66.6142.2178-62.3-167.9-78.2109-10.1111.1Q583 F584 D623 A624Q583-R621 PolarHBondContact O-NH2 3.05Å; F584-R621 PolarHBondContact O-N 3.1Å; R621-D623 WeakPolarHBondContact CB-OD1 3.39Å; R621-D623 IonicContact CZ-OD1 2.68Å; R621-D623 IonicContact CZ-OD2 2.72Å; R621-D623 IonicContact NH1-OD1 3.27Å; R621-D623 PolarHBondContact NH1-OD1 2.9Å; R621-D623 IonicContact NH1-OD2 3.43Å; R621-D623 PolarHBondContact NH1-OD2 3.4Å; R621-D623 PolarHBondContact O-N 3.04Å; R621-A624 WeakPolarHBondContact O-CB 3.45Å; R621-A624 PolarHBondContact O-N 3.26Å
622P81.5Confident83.6Confident107 Ų10752.7 Ų52.770%0.69528%0.277SS*.THydrogen-bonded Turntrans-61.1-25-179.1-25.334.5000115.1A624 P659P622-A624 VanDerWaalsContact C-N 3.32Å; P622-P659 HydrophobicContact CG-CB 4.38Å
623D81.6Confident83.4Confident113 Ų11351.5 Ų51.560%0.60427%0.267SS*.THydrogen-bonded Turntrans-85.6-0.517669.8-53.3000113.5R621R621-D623 WeakPolarHBondContact CB-OD1 3.39Å; R621-D623 IonicContact CZ-OD1 2.68Å; R621-D623 IonicContact CZ-OD2 2.72Å; R621-D623 IonicContact NH1-OD1 3.27Å; R621-D623 PolarHBondContact NH1-OD1 2.9Å; R621-D623 IonicContact NH1-OD2 3.43Å; R621-D623 PolarHBondContact NH1-OD2 3.4Å; R621-D623 PolarHBondContact O-N 3.04Å
624A77.6Confident82.8Confident21 Ų2153.7 Ų53.717%0.17428%0.275CS..  trans-60.8141.6-17700000112.3L620 R621 P622 A628L620-A624 HydrophobicContact CD1-CB 3.73Å; L620-A624 HydrophobicContact CD2-CB 4.12Å; L620-A624 HydrophobicContact CG-CB 3.72Å; R621-A624 WeakPolarHBondContact O-CB 3.45Å; R621-A624 PolarHBondContact O-N 3.26Å; P622-A624 VanDerWaalsContact C-N 3.32Å; A624-A628 HydrophobicContact CB-CB 4.25Å
625T78Confident82.1Confident77 Ų7751.1 Ų51.147%0.47226%0.262SS..  trans-60.3154.7-177.871.60000111.8N627 A628 R629T625-N627 PolarHBondContact O-N 2.96Å; T625-A628 PolarHBondContact O-N 3.28Å; T625-A628 VanDerWaalsContact O-N 3.08Å; T625-A628 PolarHBondContact OG1-N 3.19Å; T625-R629 PolarHBondContact O-N 3.21Å
626K78.4Confident81.6Confident174 Ų17451.3 Ų51.376%0.75726%0.263SS*.Hα-helixtrans-55-28.1174.5-69.1-176.9179.6177.60112.7N630K626-N630 PolarHBondContact O-N 2.88Å; K626-N630 VanDerWaalsContact O-N 3.14Å; K626-N630 PolarHBondContact O-ND2 3.4Å
627N71.3Confident81.1Confident114 Ų11455 Ų5561%0.6128%0.277SS*.Hα-helixtrans-70-55.2174.6-66.4-4.2000110.3T625 R629 N630 D631T625-N627 PolarHBondContact O-N 2.96Å; N627-R629 PolarHBondContact O-N 3.3Å; N627-R629 VanDerWaalsContact O-N 3.16Å; N627-N630 CarbonylContact O-C 3.38Å; N627-N630 WeakPolarHBondContact O-CA 3.43Å; N627-N630 WeakPolarHBondContact O-CB 3.34Å; N627-N630 PolarHBondContact O-N 3.47Å; N627-D631 PolarHBondContact O-N 3.17Å; N627-D631 VanDerWaalsContact O-OD2 3.1Å
628A70.8Confident80.5Confident8 Ų855.9 Ų55.97%0.06628%0.282CS..Hα-helixtrans-55.1-37176.300000113.1F584 L620 A624 T625 D631 F632F584-A628 HydrophobicContact CB-CB 3.83Å; F584-A628 HydrophobicContact CD1-CB 3.78Å; F584-A628 HydrophobicContact CD2-CB 4.08Å; F584-A628 HydrophobicContact CE1-CB 4.36Å; F584-A628 HydrophobicContact CG-CB 3.61Å; L620-A628 HydrophobicContact CD1-CB 4.36Å; A624-A628 HydrophobicContact CB-CB 4.25Å; T625-A628 PolarHBondContact O-N 3.28Å; T625-A628 VanDerWaalsContact O-N 3.08Å; T625-A628 PolarHBondContact OG1-N 3.19Å; A628-D631 PolarHBondContact O-N 3.45Å; A628-F632 WeakPolarHBondContact O-CB 3.41Å; A628-F632 PolarHBondContact O-N 3.39Å
629R81.4Confident80.1Confident83 Ų8355 Ų5531%0.31328%0.278SS..Hα-helixtrans-63.5-41.1172.2-164.9-170.4-174.5114.31.1113L620 T625 N627 L633 D658 L660L620-R629 HydrophobicContact CD2-CB 3.83Å; L620-R629 HydrophobicContact CD2-CG 3.82Å; T625-R629 PolarHBondContact O-N 3.21Å; N627-R629 PolarHBondContact O-N 3.3Å; N627-R629 VanDerWaalsContact O-N 3.16Å; R629-L633 VanDerWaalsContact O-CG 3.31Å; R629-L633 WeakPolarHBondContact O-CG 3.38Å; R629-L633 PolarHBondContact O-N 2.78Å; R629-L633 VanDerWaalsContact O-N 3.14Å; R629-D658 IonicContact CZ-OD1 3.39Å; R629-D658 IonicContact CZ-OD2 2.75Å; R629-D658 VanDerWaalsContact CZ-OD2 3.31Å; R629-D658 VanDerWaalsContact NH1-CG 3.26Å; R629-D658 IonicContact NH1-OD1 3.17Å; R629-D658 PolarHBondContact NH1-OD1 2.76Å; R629-D658 IonicContact NH1-OD2 2.66Å; R629-D658 PolarHBondContact NH1-OD2 3.31Å; R629-D658 VanDerWaalsContact NH2-CG 3.26Å; R629-D658 IonicContact NH2-OD1 3.16Å; R629-D658 PolarHBondContact NH2-OD1 3.42Å; R629-D658 IonicContact NH2-OD2 3.16Å; R629-D658 PolarHBondContact NH2-OD2 2.82Å; R629-L660 HydrophobicContact CG-CD1 3.55Å
630N78.2Confident79.8Confident47 Ų4754.1 Ų54.125%0.25128%0.275SS..Hα-helixtrans-68-38.6175.2-86.9-91.9000111.8R172 K626 N627 L633 K634R172-N630 WeakPolarHBondContact CD-OD1 3.46Å; R172-N630 PolarHBondContact NH1-ND2 3.31Å; R172-N630 PolarHBondContact NH1-OD1 3.24Å; K626-N630 PolarHBondContact O-N 2.88Å; K626-N630 VanDerWaalsContact O-N 3.14Å; K626-N630 PolarHBondContact O-ND2 3.4Å; N627-N630 CarbonylContact O-C 3.38Å; N627-N630 WeakPolarHBondContact O-CA 3.43Å; N627-N630 WeakPolarHBondContact O-CB 3.34Å; N627-N630 PolarHBondContact O-N 3.47Å; N630-L633 CarbonylContact O-C 3.52Å; N630-L633 PolarHBondContact O-N 2.95Å; N630-K634 WeakPolarHBondContact O-CG 3.42Å; N630-K634 PolarHBondContact O-N 2.84Å
631D71.6Confident79.5Confident46 Ų4658.2 Ų58.225%0.24629%0.29CS..Hα-helixtrans-72.7-35.8-178.2-59.9-37.9000111.4N547 N627 A628 K634 E635N547-D631 PolarHBondContact ND2-O 2.95Å; N627-D631 PolarHBondContact O-N 3.17Å; N627-D631 VanDerWaalsContact O-OD2 3.1Å; A628-D631 PolarHBondContact O-N 3.45Å; D631-K634 WeakPolarHBondContact O-CB 3.36Å; D631-K634 PolarHBondContact O-N 3.16Å; D631-K634 IonicContact OD1-NZ 2.85Å; D631-E635 PolarHBondContact O-N 3.03Å
632F81.4Confident79.6Confident10 Ų1054.9 Ų54.94%0.04428%0.277CS..Hα-helixtrans-60.6-43.4167-168-83000111.9K618 L620 A628 K634 E635 V636 L660 M662K618-F632 HydrophobicContact CB-CE2 4.47Å; K618-F632 HydrophobicContact CD-CE2 4.22Å; K618-F632 HydrophobicContact CG-CE2 4.12Å; K618-F632 WeakPolarHBondContact O-CZ 3.28Å; L620-F632 HydrophobicContact CB-CD2 3.92Å; L620-F632 HydrophobicContact CB-CE2 4.04Å; L620-F632 HydrophobicContact CB-CG 4.24Å; L620-F632 HydrophobicContact CB-CZ 4.47Å; L620-F632 HydrophobicContact CD1-CB 4.23Å; L620-F632 HydrophobicContact CD1-CD2 4.15Å; L620-F632 HydrophobicContact CD1-CG 4.43Å; L620-F632 HydrophobicContact CD2-CB 4.46Å; A628-F632 WeakPolarHBondContact O-CB 3.41Å; A628-F632 PolarHBondContact O-N 3.39Å; F632-K634 VanDerWaalsContact C-N 3.29Å; F632-K634 PolarHBondContact O-N 2.94Å; F632-E635 WeakPolarHBondContact O-CB 3.24Å; F632-E635 PolarHBondContact O-N 2.98Å; F632-V636 HydrophobicContact CD1-CG2 4.15Å; F632-V636 HydrophobicContact CE1-CG2 4.14Å; F632-V636 WeakPolarHBondContact O-CG2 3.39Å; F632-V636 PolarHBondContact O-N 2.72Å; F632-L660 HydrophobicContact CD1-CB 3.83Å; F632-L660 HydrophobicContact CD1-CD1 4.13Å; F632-L660 HydrophobicContact CE1-CB 3.6Å; F632-L660 HydrophobicContact CZ-CB 4.29Å; F632-L660 WeakPolarHBondContact CZ-O 3.43Å; F632-M662 HydrophobicContact CD1-CE 4.37Å; F632-M662 HydrophobicContact CD2-CE 4.06Å; F632-M662 HydrophobicContact CE1-CE 4.05Å; F632-M662 HydrophobicContact CE1-CG 4.04Å; F632-M662 HydrophobicContact CE2-CE 3.75Å; F632-M662 HydrophobicContact CG-CE 4.37Å; F632-M662 HydrophobicContact CZ-CB 4.44Å; F632-M662 HydrophobicContact CZ-CE 3.74Å; F632-M662 HydrophobicContact CZ-CG 4.07Å
633L83Confident79.9Confident53 Ų5355.4 Ų55.428%0.27727%0.269SS..Hα-helixtrans-72.1-18.1176.3-70.3171.9000113.9R629 N630 K637 V655 L660R629-L633 VanDerWaalsContact O-CG 3.31Å; R629-L633 WeakPolarHBondContact O-CG 3.38Å; R629-L633 PolarHBondContact O-N 2.78Å; R629-L633 VanDerWaalsContact O-N 3.14Å; N630-L633 CarbonylContact O-C 3.52Å; N630-L633 PolarHBondContact O-N 2.95Å; L633-K637 WeakPolarHBondContact O-CD 3.47Å; L633-K637 WeakPolarHBondContact O-CG 3.37Å; L633-V655 HydrophobicContact CD2-CB 4.18Å; L633-V655 HydrophobicContact CD2-CG1 3.89Å; L633-L660 HydrophobicContact CD1-CD1 4.19Å; L633-L660 HydrophobicContact CD2-CD1 4Å; L633-L660 HydrophobicContact CG-CD1 3.89Å
634K78.7Confident80.5Confident65 Ų6551.5 Ų51.528%0.28325%0.248SC..Hα-helixtrans-76.6-43.7166.3-74.7170.4176.51760110.6D171 N630 D631 F632 V636 K637 I638D171-K634 VanDerWaalsContact OD2-CE 3.23Å; D171-K634 WeakPolarHBondContact OD2-CE 3.46Å; D171-K634 IonicContact OD2-NZ 3.81Å; D171-K634 PolarHBondContact OD2-NZ 3.4Å; N630-K634 WeakPolarHBondContact O-CG 3.42Å; N630-K634 PolarHBondContact O-N 2.84Å; D631-K634 WeakPolarHBondContact O-CB 3.36Å; D631-K634 PolarHBondContact O-N 3.16Å; D631-K634 IonicContact OD1-NZ 2.85Å; F632-K634 VanDerWaalsContact C-N 3.29Å; F632-K634 PolarHBondContact O-N 2.94Å; K634-V636 PolarHBondContact O-N 3.28Å; K634-K637 PolarHBondContact O-N 3.21Å; K634-K637 VanDerWaalsContact O-N 3.16Å; K634-I638 WeakPolarHBondContact O-CG1 3.47Å; K634-I638 PolarHBondContact O-N 3.16Å
635E79.4Confident81.2Confident8 Ų854.9 Ų54.94%0.03727%0.268CS..Hα-helixtrans-56-48.2174.5-162.6-172.9160.700111.2K618 D631 F632 K637 I638 M639 M662K618-E635 IonicContact NZ-OE1 2.72Å; K618-E635 PolarHBondContact NZ-OE1 3.02Å; K618-E635 IonicContact NZ-OE2 3.85Å; K618-E635 PolarHBondContact NZ-OE2 2.73Å; D631-E635 PolarHBondContact O-N 3.03Å; F632-E635 WeakPolarHBondContact O-CB 3.24Å; F632-E635 PolarHBondContact O-N 2.98Å; E635-K637 VanDerWaalsContact C-N 3.31Å; E635-K637 PolarHBondContact O-N 2.75Å; E635-I638 WeakPolarHBondContact O-CB 3.49Å; E635-I638 PolarHBondContact O-N 2.93Å; E635-I638 VanDerWaalsContact O-N 3.11Å; E635-M639 HydrophobicContact CG-CG 4.26Å; E635-M639 VanDerWaalsContact O-CB 3.32Å; E635-M639 WeakPolarHBondContact O-CB 3.33Å; E635-M639 VanDerWaalsContact O-CG 3.29Å; E635-M639 WeakPolarHBondContact O-CG 3.27Å; E635-M639 PolarHBondContact O-N 2.9Å; E635-M662 HydrophobicContact CB-CE 4.02Å; E635-M662 HydrophobicContact CB-SD 4.38Å; E635-M662 HydrophobicContact CG-CE 3.81Å; E635-M662 HydrophobicContact CG-SD 4.25Å; E635-M662 WeakPolarHBondContact OE1-CE 3.47Å; E635-M662 WeakPolarHBondContact OE2-CE 3.31Å
636V83.3Confident82.1Confident5 Ų552 Ų523%0.0325%0.25CC..Hα-helixtrans-49.1-48.7173.1166.30000112.5F632 K634 I638 M639 S640 V653 V655 M662F632-V636 HydrophobicContact CD1-CG2 4.15Å; F632-V636 HydrophobicContact CE1-CG2 4.14Å; F632-V636 WeakPolarHBondContact O-CG2 3.39Å; F632-V636 PolarHBondContact O-N 2.72Å; K634-V636 PolarHBondContact O-N 3.28Å; V636-I638 VanDerWaalsContact C-N 3.34Å; V636-M639 PolarHBondContact O-N 2.8Å; V636-S640 WeakPolarHBondContact O-CB 3.38Å; V636-S640 PolarHBondContact O-N 3.17Å; V636-V653 HydrophobicContact CG1-CG1 4Å; V636-V653 HydrophobicContact CG2-CG1 4.36Å; V636-V655 HydrophobicContact CG2-CG1 4.32Å; V636-M662 HydrophobicContact CB-SD 4.21Å; V636-M662 HydrophobicContact CG2-CE 4.49Å; V636-M662 HydrophobicContact CG2-CG 3.51Å; V636-M662 HydrophobicContact CG2-SD 3.51Å; V636-M662 VanDerWaalsContact CG2-SD 3.51Å
637K81.2Confident82.9Confident84 Ų8443.8 Ų43.837%0.36521%0.214SC..Hα-helixtrans-75.1-22.8-176.3-69.9172.1-177.4176.70113.6L633 K634 E635 S640L633-K637 WeakPolarHBondContact O-CD 3.47Å; L633-K637 WeakPolarHBondContact O-CG 3.37Å; K634-K637 PolarHBondContact O-N 3.21Å; K634-K637 VanDerWaalsContact O-N 3.16Å; E635-K637 VanDerWaalsContact C-N 3.31Å; E635-K637 PolarHBondContact O-N 2.75Å; K637-S640 PolarHBondContact O-OG 2.97Å
638I79.6Confident83.8Confident20 Ų2038.5 Ų38.510%0.10319%0.186CC..Hα-helixtrans-74.2-57.5169.9-74.1167.7000108.1Y549 V551 K634 E635 V636 S640 R641 L642 F725Y549-I638 HydrophobicContact CD2-CD1 4.5Å; Y549-I638 HydrophobicContact CD2-CG2 3.8Å; Y549-I638 HydrophobicContact CE2-CG2 4.18Å; Y549-I638 HydrophobicContact CG-CG2 4.48Å; V551-I638 HydrophobicContact CG2-CD1 3.67Å; V551-I638 HydrophobicContact CG2-CG1 3.91Å; K634-I638 WeakPolarHBondContact O-CG1 3.47Å; K634-I638 PolarHBondContact O-N 3.16Å; E635-I638 WeakPolarHBondContact O-CB 3.49Å; E635-I638 PolarHBondContact O-N 2.93Å; E635-I638 VanDerWaalsContact O-N 3.11Å; V636-I638 VanDerWaalsContact C-N 3.34Å; I638-S640 VanDerWaalsContact C-N 3.3Å; I638-S640 PolarHBondContact O-N 3.09Å; I638-R641 WeakPolarHBondContact O-CB 3.43Å; I638-R641 PolarHBondContact O-N 2.83Å; I638-L642 HydrophobicContact CG2-CD1 4.07Å; I638-F725 HydrophobicContact CB-CE2 4.49Å; I638-F725 HydrophobicContact CD1-CE2 4.46Å; I638-F725 HydrophobicContact CG1-CE2 4.32Å; I638-F725 HydrophobicContact CG2-CE2 3.48Å; I638-F725 VanDerWaalsContact CG2-CE2 3.48Å; I638-F725 HydrophobicContact CG2-CZ 3.43Å; I638-F725 VanDerWaalsContact CG2-CZ 3.43Å
639M81.8Confident84.7Confident5 Ų541.1 Ų41.13%0.02519%0.194CC..Hα-helixtrans-56.5-37.3-177.2-74.6-71-73.900113.4E635 V636 R641 L642 I648 L650 M662 T664E635-M639 HydrophobicContact CG-CG 4.26Å; E635-M639 VanDerWaalsContact O-CB 3.32Å; E635-M639 WeakPolarHBondContact O-CB 3.33Å; E635-M639 VanDerWaalsContact O-CG 3.29Å; E635-M639 WeakPolarHBondContact O-CG 3.27Å; E635-M639 PolarHBondContact O-N 2.9Å; V636-M639 PolarHBondContact O-N 2.8Å; M639-R641 PolarHBondContact O-N 3.05Å; M639-R641 VanDerWaalsContact O-N 3.1Å; M639-L642 PolarHBondContact O-N 2.81Å; M639-L642 VanDerWaalsContact O-N 3.16Å; M639-L642 HydrophobicContact SD-CD1 4.25Å; M639-I648 HydrophobicContact CE-CG1 4.37Å; M639-I648 HydrophobicContact CE-CG2 3.68Å; M639-I648 HydrophobicContact SD-CG2 4Å; M639-L650 HydrophobicContact CB-CB 4.26Å; M639-L650 HydrophobicContact CB-CD1 4.39Å; M639-L650 HydrophobicContact CB-CD2 4.18Å; M639-M662 HydrophobicContact CG-SD 4.42Å; M639-T664 HydrophobicContact CE-CG2 3.8Å
640S83.6Confident85.1Confident13 Ų1338.1 Ų38.19%0.09118%0.184CC..THydrogen-bonded Turntrans-64.7-14.2177.4730000114.1V636 K637 I638V636-S640 WeakPolarHBondContact O-CB 3.38Å; V636-S640 PolarHBondContact O-N 3.17Å; K637-S640 PolarHBondContact O-OG 2.97Å; I638-S640 VanDerWaalsContact C-N 3.3Å; I638-S640 PolarHBondContact O-N 3.09Å
641R82.2Confident85.7Confident95 Ų9536 Ų3636%0.35817%0.173SC..THydrogen-bonded Turntrans-103.3-6.8179.4-58.2179.364.7-144.4-6.3113.3L554 I638 M639 Y719L554-R641 VanDerWaalsContact CD1-NH1 3.35Å; I638-R641 WeakPolarHBondContact O-CB 3.43Å; I638-R641 PolarHBondContact O-N 2.83Å; M639-R641 PolarHBondContact O-N 3.05Å; M639-R641 VanDerWaalsContact O-N 3.1Å; R641-Y719 PolarHBondContact O-OH 3.43Å
642L86.3Confident86.6Confident5 Ų533.8 Ų33.83%0.02616%0.161CC..  trans-92.1106.9-178.7-58.4-178.3000109.9I638 M639 I647 Y719 L720 L723 F725I638-L642 HydrophobicContact CG2-CD1 4.07Å; M639-L642 PolarHBondContact O-N 2.81Å; M639-L642 VanDerWaalsContact O-N 3.16Å; M639-L642 HydrophobicContact SD-CD1 4.25Å; L642-I647 HydrophobicContact CB-CG2 3.89Å; L642-I647 HydrophobicContact CD1-CG2 3.94Å; L642-I647 HydrophobicContact CG-CG2 4.44Å; L642-Y719 HydrophobicContact CD2-CE1 4.17Å; L642-L720 HydrophobicContact CD1-CD2 4.5Å; L642-L720 HydrophobicContact CD2-CD2 3.74Å; L642-L723 HydrophobicContact CD2-CD1 3.86Å; L642-F725 HydrophobicContact CD1-CZ 4.46Å
643K89.1Confident87.2Confident118 Ų11833.4 Ų33.451%0.51316%0.159SC..  trans-133.675.7-173.9-66.4-174.5177.7-178.80110.6D561 Y719D561-K643 IonicContact OD1-NZ 3.24Å; D561-K643 PolarHBondContact OD1-NZ 3.19Å; D561-K643 WeakPolarHBondContact OD2-CE 3.44Å; D561-K643 IonicContact OD2-NZ 2.7Å; D561-K643 PolarHBondContact OD2-NZ 3.1Å; K643-Y719 PolarHBondContact N-OH 3.11Å
644D93.3Very high87.6Confident30 Ų3030.9 Ų30.916%0.1615%0.146CC..  trans-140.5146.6178.7-178.2-90.6000110.6N646 I647 Y719D644-N646 PolarHBondContact O-N 3.39Å; D644-N646 WeakPolarHBondContact OD1-CA 3.46Å; D644-N646 PolarHBondContact OD1-N 3.28Å; D644-I647 HydrophobicContact CB-CB 4.27Å; D644-I647 HydrophobicContact CB-CG1 3.95Å; D644-I647 PolarHBondContact O-N 3.38Å; D644-Y719 HydrophobicContact CB-CD1 3.61Å; D644-Y719 HydrophobicContact CB-CD2 3.78Å; D644-Y719 HydrophobicContact CB-CE1 3.94Å; D644-Y719 HydrophobicContact CB-CE2 4.09Å; D644-Y719 HydrophobicContact CB-CG 3.52Å
645P93.4Very high88.1Confident93 Ų9329.7 Ų29.760%0.60414%0.144SC*.THydrogen-bonded Turntrans-56.9-31.9178.1-26.836.7000114.2K744P645-K744 PolarHBondContact O-NZ 3.1Å
646N96.6Very high88.5Confident16 Ų1636.1 Ų36.19%0.08617%0.174CC..THydrogen-bonded Turntrans-10413.6-175.4-60.9120.2000114.2D644 Q712 S715 I743 K744 I745D644-N646 PolarHBondContact O-N 3.39Å; D644-N646 WeakPolarHBondContact OD1-CA 3.46Å; D644-N646 PolarHBondContact OD1-N 3.28Å; N646-Q712 VanDerWaalsContact CB-O 3.29Å; N646-Q712 WeakPolarHBondContact CB-O 3.39Å; N646-Q712 WeakPolarHBondContact ND2-CB 3.32Å; N646-Q712 WeakPolarHBondContact ND2-CG 3.36Å; N646-Q712 PolarHBondContact ND2-OE1 3.15Å; N646-Q712 VanDerWaalsContact ND2-OE1 3.09Å; N646-S715 WeakPolarHBondContact OD1-CB 3.49Å; N646-S715 PolarHBondContact OD1-OG 3.27Å; N646-I743 WeakPolarHBondContact CA-O 3.38Å; N646-I743 PolarHBondContact ND2-O 3.47Å; N646-K744 WeakPolarHBondContact O-CA 3.34Å; N646-I745 PolarHBondContact O-N 3.26Å
647I94.1Very high88.6Confident2 Ų241.6 Ų41.61%0.0120%0.203CC..BIsolated β-bridgetrans-112150.7167.3-56.6-61.7000109.8L642 D644 R649 Y719 L720 K744 I745L642-I647 HydrophobicContact CB-CG2 3.89Å; L642-I647 HydrophobicContact CD1-CG2 3.94Å; L642-I647 HydrophobicContact CG-CG2 4.44Å; D644-I647 HydrophobicContact CB-CB 4.27Å; D644-I647 HydrophobicContact CB-CG1 3.95Å; D644-I647 PolarHBondContact O-N 3.38Å; I647-R649 PolarHBondContact O-N 3.04Å; I647-Y719 HydrophobicContact CG1-CD1 4.08Å; I647-L720 HydrophobicContact CD1-CD1 4.03Å; I647-L720 HydrophobicContact CD1-CD2 4.05Å; I647-L720 HydrophobicContact CD1-CG 3.89Å; I647-L720 HydrophobicContact CG1-CD2 4.28Å; I647-K744 PolarHBondContact O-NZ 2.88Å; I647-I745 HydrophobicContact CD1-CB 3.96Å; I647-I745 HydrophobicContact CD1-CD1 4.11Å; I647-I745 HydrophobicContact CD1-CG1 4.3Å
648I90.9Very high88.9Confident2 Ų241.3 Ų41.31%0.0121%0.206CC..  trans-64.5130172.8-170.162.1000110.8M639 T664 K744 I745 A746 F748M639-I648 HydrophobicContact CE-CG1 4.37Å; M639-I648 HydrophobicContact CE-CG2 3.68Å; M639-I648 HydrophobicContact SD-CG2 4Å; I648-T664 HydrophobicContact CG1-CG2 4.06Å; I648-K744 HydrophobicContact CD1-CD 4.26Å; I648-I745 WeakPolarHBondContact CG2-O 3.43Å; I648-I745 PolarHBondContact N-O 2.8Å; I648-A746 HydrophobicContact CB-CB 3.93Å; I648-A746 HydrophobicContact CG1-CB 4.49Å; I648-A746 HydrophobicContact CG2-CB 3.66Å; I648-F748 HydrophobicContact CD1-CZ 4.47Å; I648-F748 HydrophobicContact CG1-CE2 4.04Å; I648-F748 HydrophobicContact CG1-CZ 3.96Å
649R89.1Confident89.5Confident64 Ų6442.3 Ų42.324%0.24221%0.213CC..  trans-106.7130.6-168.5-179.6178.868.5123.31110.9P604 I647 L651 T664 D665P604-R649 PolarHBondContact O-NH1 3.02Å; P604-R649 PolarHBondContact O-NH2 2.9Å; I647-R649 PolarHBondContact O-N 3.04Å; R649-L651 HydrophobicContact CG-CD2 4.44Å; R649-T664 VanDerWaalsContact O-CA 3.28Å; R649-T664 WeakPolarHBondContact O-CA 3.4Å; R649-T664 VanDerWaalsContact O-CB 3.3Å; R649-T664 WeakPolarHBondContact O-CB 3.41Å; R649-D665 WeakPolarHBondContact CB-OD2 3.33Å; R649-D665 IonicContact CZ-OD1 3.34Å; R649-D665 IonicContact CZ-OD2 2.69Å; R649-D665 IonicContact NE-OD1 3.58Å; R649-D665 IonicContact NE-OD2 2.75Å; R649-D665 PolarHBondContact NE-OD2 3.37Å; R649-D665 IonicContact NH2-OD1 3.24Å; R649-D665 PolarHBondContact NH2-OD1 2.9Å; R649-D665 IonicContact NH2-OD2 3.62Å; R649-D665 PolarHBondContact NH2-OD2 3.32Å; R649-D665 PolarHBondContact O-N 2.72Å
650L90.1Very high89.9Confident19 Ų1942.1 Ų42.110%0.09921%0.212CC..EExtended strand (participates in β ladder)trans-75.2125.6172-166.368.7000110.2M639 V653 M662M639-L650 HydrophobicContact CB-CB 4.26Å; M639-L650 HydrophobicContact CB-CD1 4.39Å; M639-L650 HydrophobicContact CB-CD2 4.18Å; L650-V653 HydrophobicContact CD1-CG1 4.09Å; L650-V653 HydrophobicContact CD2-CG1 3.9Å; L650-V653 HydrophobicContact CG-CG1 4.32Å; L650-M662 HydrophobicContact CD1-CB 3.88Å; L650-M662 HydrophobicContact CD1-CG 3.99Å; L650-M662 HydrophobicContact CD1-SD 4.41Å
651L90.4Very high90.3Very high3 Ų341.6 Ų41.62%0.01621%0.209CC..EExtended strand (participates in β ladder)trans-99.7-23.9177.7-57.5-174.4000113.1L605 V615 R649 I663L605-L651 HydrophobicContact CD2-CB 4.05Å; L605-L651 HydrophobicContact CD2-CD1 4.1Å; V615-L651 HydrophobicContact CG1-CD1 3.78Å; R649-L651 HydrophobicContact CG-CD2 4.44Å; L651-I663 HydrophobicContact CB-CG2 4.24Å; L651-I663 PolarHBondContact N-O 3.37Å
652G91Very high90.7Very high0 Ų037.2 Ų37.20%019%0.193CC..EExtended strand (participates in β ladder)trans175.2173.3-177.100000111.1I663G652-I663 PolarHBondContact N-O 3.48Å; G652-I663 WeakPolarHBondContact O-CD1 3.36Å; G652-I663 PolarHBondContact O-N 3.22Å
653V92.9Very high91.1Very high1 Ų137 Ų371%0.00619%0.192CC..EExtended strand (participates in β ladder)trans-140.8155.8179.1-65.30000110.2P564 D567 F568 V636 L650 V655 C661 M662P564-V653 HydrophobicContact CB-CG2 4.19Å; P564-V653 HydrophobicContact CG-CG2 4.07Å; D567-V653 CarbonylContact C-O 3.3Å; D567-V653 WeakPolarHBondContact CA-O 3.38Å; F568-V653 WeakPolarHBondContact CB-O 3.34Å; F568-V653 PolarHBondContact N-O 3.08Å; V636-V653 HydrophobicContact CG1-CG1 4Å; V636-V653 HydrophobicContact CG2-CG1 4.36Å; L650-V653 HydrophobicContact CD1-CG1 4.09Å; L650-V653 HydrophobicContact CD2-CG1 3.9Å; L650-V653 HydrophobicContact CG-CG1 4.32Å; V653-V655 HydrophobicContact CB-CG1 4.15Å; V653-V655 HydrophobicContact CB-CG2 4.41Å; V653-V655 HydrophobicContact CG2-CG2 3.89Å; V653-C661 CarbonylContact C-O 3.51Å; V653-C661 WeakPolarHBondContact CA-O 3.36Å; V653-M662 HydrophobicContact CG1-CG 4.27Å
654C92.5Very high91.2Very high1 Ų131.6 Ų31.61%0.00717%0.168CC..EExtended strand (participates in β ladder)trans-123.1101.6162.3-51.60000107.3D567 F568 L660 C661D567-C654 WeakPolarHBondContact OD2-CA 3.02Å; F568-C654 PolarHBondContact O-SG 3.48Å; C654-L660 CarbonylContact O-C 3.44Å; C654-L660 WeakPolarHBondContact O-CA 3.14Å; C654-C661 HydrophobicContact CB-CB 3.95Å; C654-C661 PolarHBondContact N-O 3.3Å; C654-C661 PolarHBondContact O-N 3.19Å
655V89.9Confident91.1Very high39 Ų3931.5 Ų31.524%0.23617%0.168CC..  trans-133.5-3.1-172.4-67.30000115.2D567 L633 V636 V653 L660D567-V655 WeakPolarHBondContact OD1-CG2 3.42Å; D567-V655 PolarHBondContact OD1-N 3.02Å; D567-V655 PolarHBondContact OD2-N 3.47Å; L633-V655 HydrophobicContact CD2-CB 4.18Å; L633-V655 HydrophobicContact CD2-CG1 3.89Å; V636-V655 HydrophobicContact CG2-CG1 4.32Å; V653-V655 HydrophobicContact CB-CG1 4.15Å; V653-V655 HydrophobicContact CB-CG2 4.41Å; V653-V655 HydrophobicContact CG2-CG2 3.89Å; V655-L660 HydrophobicContact CB-CD2 4.24Å; V655-L660 HydrophobicContact CG1-CD2 4.32Å
656Q86.1Confident91Very high143 Ų14330.1 Ų30.167%0.66815%0.151SC*.SBendtrans-70.7-51.3170.2-58.5-63-28.200110.5D567D567-Q656 HydrophobicContact CB-CG 4.33Å; D567-Q656 PolarHBondContact OD2-N 3.07Å
657D86.4Confident90.7Very high121 Ų12130.1 Ų30.165%0.64715%0.151SC*.SBendtrans-113.4154-179.2-63.9-51.9000111.7R570R570-D657 PolarHBondContact NH2-O 3.15Å
658D88.1Confident90.5Very high78 Ų7835 Ų3542%0.41717%0.173SC..SBendtrans-78.4155.8175.7-77.8-45000113.4R629R629-D658 IonicContact CZ-OD1 3.39Å; R629-D658 IonicContact CZ-OD2 2.75Å; R629-D658 VanDerWaalsContact CZ-OD2 3.31Å; R629-D658 VanDerWaalsContact NH1-CG 3.26Å; R629-D658 IonicContact NH1-OD1 3.17Å; R629-D658 PolarHBondContact NH1-OD1 2.76Å; R629-D658 IonicContact NH1-OD2 2.66Å; R629-D658 PolarHBondContact NH1-OD2 3.31Å; R629-D658 VanDerWaalsContact NH2-CG 3.26Å; R629-D658 IonicContact NH2-OD1 3.16Å; R629-D658 PolarHBondContact NH2-OD1 3.42Å; R629-D658 IonicContact NH2-OD2 3.16Å; R629-D658 PolarHBondContact NH2-OD2 2.82Å
659P90.9Very high90.5Very high40 Ų4038 Ų3826%0.2619%0.189SC..SBendcis-75.5143.1-5.830.6-34.4000112R570 I619 L620 P622 C661R570-P659 VanDerWaalsContact CZ-O 3.23Å; R570-P659 PolarHBondContact NH1-O 3.36Å; R570-P659 PolarHBondContact NH2-O 3.09Å; I619-P659 HydrophobicContact CG2-CB 3.76Å; I619-P659 HydrophobicContact CG2-CG 3.87Å; L620-P659 WeakPolarHBondContact O-CB 3.46Å; P622-P659 HydrophobicContact CG-CB 4.38Å; P659-C661 PolarHBondContact O-N 2.93Å; P659-C661 PolarHBondContact O-SG 3.47Å; P659-C661 VanDerWaalsContact O-SG 3.39Å
660L91.2Very high90.6Very high1 Ų136.4 Ų36.41%0.00519%0.193CC..PPolyproline II helixtrans-62.3132.5178.8-54.5-174.7000111.3I619 L620 R629 F632 L633 C654 V655I619-L660 WeakPolarHBondContact CA-O 3.5Å; L620-L660 HydrophobicContact CB-CB 4.11Å; L620-L660 HydrophobicContact CD2-CB 4.45Å; L620-L660 HydrophobicContact CD2-CD1 3.98Å; L620-L660 HydrophobicContact CD2-CG 4.3Å; L620-L660 PolarHBondContact N-O 2.88Å; R629-L660 HydrophobicContact CG-CD1 3.55Å; F632-L660 HydrophobicContact CD1-CB 3.83Å; F632-L660 HydrophobicContact CD1-CD1 4.13Å; F632-L660 HydrophobicContact CE1-CB 3.6Å; F632-L660 HydrophobicContact CZ-CB 4.29Å; F632-L660 WeakPolarHBondContact CZ-O 3.43Å; L633-L660 HydrophobicContact CD1-CD1 4.19Å; L633-L660 HydrophobicContact CD2-CD1 4Å; L633-L660 HydrophobicContact CG-CD1 3.89Å; C654-L660 CarbonylContact O-C 3.44Å; C654-L660 WeakPolarHBondContact O-CA 3.14Å; V655-L660 HydrophobicContact CB-CD2 4.24Å; V655-L660 HydrophobicContact CG1-CD2 4.32Å
661C92.4Very high90.7Very high3 Ų336.3 Ų36.32%0.0219%0.193CC..EExtended strand (participates in β ladder)trans-128146.1179.8-60.70000113.2R570 V617 K618 V653 C654 P659R570-C661 PolarHBondContact NH1-SG 2.94Å; V617-C661 HydrophobicContact CG1-CB 3.9Å; K618-C661 CarbonylContact O-C 3.59Å; K618-C661 VanDerWaalsContact O-CA 3.25Å; K618-C661 WeakPolarHBondContact O-CA 3.33Å; V653-C661 CarbonylContact C-O 3.51Å; V653-C661 WeakPolarHBondContact CA-O 3.36Å; C654-C661 HydrophobicContact CB-CB 3.95Å; C654-C661 PolarHBondContact N-O 3.3Å; C654-C661 PolarHBondContact O-N 3.19Å; P659-C661 PolarHBondContact O-N 2.93Å; P659-C661 PolarHBondContact O-SG 3.47Å; P659-C661 VanDerWaalsContact O-SG 3.39Å
662M90.8Very high90.9Very high3 Ų336.1 Ų36.12%0.01519%0.192CC..EExtended strand (participates in β ladder)trans-118.2132.2161.3-75.2-178.8-71.400109V617 K618 F632 E635 V636 M639 L650 V653V617-M662 CarbonylContact C-O 3.34Å; V617-M662 VanDerWaalsContact CA-O 3.31Å; V617-M662 WeakPolarHBondContact CA-O 3.49Å; K618-M662 HydrophobicContact CB-CB 4.46Å; K618-M662 HydrophobicContact CD-CE 3.73Å; K618-M662 PolarHBondContact N-O 3.03Å; K618-M662 PolarHBondContact O-N 3.48Å; F632-M662 HydrophobicContact CD1-CE 4.37Å; F632-M662 HydrophobicContact CD2-CE 4.06Å; F632-M662 HydrophobicContact CE1-CE 4.05Å; F632-M662 HydrophobicContact CE1-CG 4.04Å; F632-M662 HydrophobicContact CE2-CE 3.75Å; F632-M662 HydrophobicContact CG-CE 4.37Å; F632-M662 HydrophobicContact CZ-CB 4.44Å; F632-M662 HydrophobicContact CZ-CE 3.74Å; F632-M662 HydrophobicContact CZ-CG 4.07Å; E635-M662 HydrophobicContact CB-CE 4.02Å; E635-M662 HydrophobicContact CB-SD 4.38Å; E635-M662 HydrophobicContact CG-CE 3.81Å; E635-M662 HydrophobicContact CG-SD 4.25Å; E635-M662 WeakPolarHBondContact OE1-CE 3.47Å; E635-M662 WeakPolarHBondContact OE2-CE 3.31Å; V636-M662 HydrophobicContact CB-SD 4.21Å; V636-M662 HydrophobicContact CG2-CE 4.49Å; V636-M662 HydrophobicContact CG2-CG 3.51Å; V636-M662 HydrophobicContact CG2-SD 3.51Å; V636-M662 VanDerWaalsContact CG2-SD 3.51Å; M639-M662 HydrophobicContact CG-SD 4.42Å; L650-M662 HydrophobicContact CD1-CB 3.88Å; L650-M662 HydrophobicContact CD1-CG 3.99Å; L650-M662 HydrophobicContact CD1-SD 4.41Å; V653-M662 HydrophobicContact CG1-CG 4.27Å
663I93.2Very high91.1Very high1 Ų137.4 Ų37.41%0.00520%0.198CC..EExtended strand (participates in β ladder)trans-106.9126.8177.6-56.488.2000108.3F568 L573 V615 A616 V617 L651 G652F568-I663 HydrophobicContact CB-CD1 3.88Å; F568-I663 HydrophobicContact CD1-CD1 4.41Å; F568-I663 HydrophobicContact CG-CD1 4.13Å; L573-I663 HydrophobicContact CD1-CD1 4.34Å; L573-I663 HydrophobicContact CD1-CG1 4.07Å; L573-I663 HydrophobicContact CD2-CG1 4.32Å; V615-I663 HydrophobicContact CB-CG2 3.62Å; V615-I663 HydrophobicContact CG1-CG2 3.98Å; V615-I663 HydrophobicContact CG2-CG2 3.68Å; A616-I663 WeakPolarHBondContact O-CA 3.38Å; V617-I663 HydrophobicContact CG1-CG1 4.36Å; V617-I663 HydrophobicContact CG2-CG1 4.18Å; V617-I663 HydrophobicContact CG2-CG2 4.46Å; L651-I663 HydrophobicContact CB-CG2 4.24Å; L651-I663 PolarHBondContact N-O 3.37Å; G652-I663 PolarHBondContact N-O 3.48Å; G652-I663 WeakPolarHBondContact O-CD1 3.36Å; G652-I663 PolarHBondContact O-N 3.22Å
664T92.6Very high91Very high3 Ų342 Ų422%0.01822%0.22CC..EExtended strand (participates in β ladder)trans-125.4166176.566.80000111.8V615 A616 M639 I648 R649 Y666 F748V615-T664 WeakPolarHBondContact CB-O 3.5Å; A616-T664 PolarHBondContact N-O 3.11Å; A616-T664 VanDerWaalsContact N-O 3.11Å; A616-T664 PolarHBondContact O-N 3.41Å; M639-T664 HydrophobicContact CE-CG2 3.8Å; I648-T664 HydrophobicContact CG1-CG2 4.06Å; R649-T664 VanDerWaalsContact O-CA 3.28Å; R649-T664 WeakPolarHBondContact O-CA 3.4Å; R649-T664 VanDerWaalsContact O-CB 3.3Å; R649-T664 WeakPolarHBondContact O-CB 3.41Å; T664-Y666 PolarHBondContact O-N 3.14Å; T664-F748 HydrophobicContact CG2-CZ 4.43Å
665D89.6Confident91.1Very high29 Ų2943.1 Ų43.116%0.15523%0.225CC..EExtended strand (participates in β ladder)trans-50.8136.9165.2-67.4-50.5000109.6R649R649-D665 WeakPolarHBondContact CB-OD2 3.33Å; R649-D665 IonicContact CZ-OD1 3.34Å; R649-D665 IonicContact CZ-OD2 2.69Å; R649-D665 IonicContact NE-OD1 3.58Å; R649-D665 IonicContact NE-OD2 2.75Å; R649-D665 PolarHBondContact NE-OD2 3.37Å; R649-D665 IonicContact NH2-OD1 3.24Å; R649-D665 PolarHBondContact NH2-OD1 2.9Å; R649-D665 IonicContact NH2-OD2 3.62Å; R649-D665 PolarHBondContact NH2-OD2 3.32Å; R649-D665 PolarHBondContact O-N 2.72Å
666Y91.4Very high91.4Very high64 Ų6441.3 Ų41.325%0.25121%0.214SC..  trans-81.3144.8170.6177.1-121.4000110.4L579 L589 L614 T664 E668L579-Y666 HydrophobicContact CD1-CD2 4.04Å; L579-Y666 HydrophobicContact CD1-CE2 3.79Å; L579-Y666 HydrophobicContact CD2-CE2 4.09Å; L589-Y666 HydrophobicContact CD1-CD1 3.89Å; L589-Y666 HydrophobicContact CD1-CD2 3.56Å; L589-Y666 HydrophobicContact CD1-CE1 4.05Å; L589-Y666 HydrophobicContact CD1-CE2 3.74Å; L589-Y666 HydrophobicContact CD1-CG 3.65Å; L589-Y666 HydrophobicContact CD2-CE1 4.45Å; L614-Y666 HydrophobicContact CB-CD1 3.84Å; L614-Y666 HydrophobicContact CB-CG 4.28Å; L614-Y666 HydrophobicContact CD1-CD1 4.04Å; L614-Y666 HydrophobicContact CD1-CE1 4.13Å; T664-Y666 PolarHBondContact O-N 3.14Å; Y666-E668 HydrophobicContact CD1-CB 4.45Å; Y666-E668 HydrophobicContact CE1-CB 3.93Å
667M91.7Very high91.7Very high16 Ų1637 Ų378%0.07920%0.199CC..  trans-122.996.3-177-63.8-64.9-78.400108N669 G670 L736 V737 T742 K744M667-N669 VanDerWaalsContact C-N 3.25Å; M667-N669 PolarHBondContact O-N 3.07Å; M667-G670 PolarHBondContact O-N 3.15Å; M667-L736 HydrophobicContact CB-CB 3.76Å; M667-L736 HydrophobicContact CB-CD1 4.08Å; M667-L736 HydrophobicContact CE-CB 4.17Å; M667-L736 WeakPolarHBondContact CE-O 3.33Å; M667-L736 HydrophobicContact CG-CB 3.75Å; M667-L736 HydrophobicContact CG-CD1 3.95Å; M667-V737 CarbonylContact C-O 3.58Å; M667-T742 WeakPolarHBondContact CE-O 3.44Å; M667-K744 HydrophobicContact CE-CB 3.87Å; M667-K744 HydrophobicContact CE-CD 4Å; M667-K744 HydrophobicContact CE-CG 3.8Å; M667-K744 HydrophobicContact SD-CD 3.8Å; M667-K744 HydrophobicContact SD-CG 4.3Å
668E89.1Confident91.9Very high103 Ų10333.9 Ų33.948%0.48119%0.191SC..THydrogen-bonded Turntrans-62.9-22.7-164.957.9171.8-15300115.7Y666 E739Y666-E668 HydrophobicContact CD1-CB 4.45Å; Y666-E668 HydrophobicContact CE1-CB 3.93Å; E668-E739 WeakPolarHBondContact OE1-CG 3.25Å
669N91.9Very high92.1Very high65 Ų6530.9 Ų30.935%0.34817%0.174SC..THydrogen-bonded Turntrans-99.513-176.1-70.4-59.2000112.7M667 F675 V737 G738M667-N669 VanDerWaalsContact C-N 3.25Å; M667-N669 PolarHBondContact O-N 3.07Å; N669-F675 HydrophobicContact CB-CD2 3.73Å; N669-F675 HydrophobicContact CB-CE2 3.79Å; N669-V737 WeakPolarHBondContact CA-O 3.45Å; N669-V737 HydrophobicContact CB-CB 3.79Å; N669-V737 HydrophobicContact CB-CG1 3.81Å; N669-V737 WeakPolarHBondContact CB-O 3.33Å; N669-V737 PolarHBondContact N-O 3.18Å; N669-G738 PolarHBondContact ND2-O 2.98Å
670G90.8Very high92Very high31 Ų3132.4 Ų32.432%0.3218%0.178SC..  trans74.1-149.6173.900000113.8M667 L736 V737M667-G670 PolarHBondContact O-N 3.15Å; G670-L736 CarbonylContact O-C 3.56Å; G670-L736 WeakPolarHBondContact O-CA 3.46Å; G670-V737 PolarHBondContact O-N 2.65Å
671D91.4Very high91.8Very high17 Ų1735.8 Ų35.89%0.09120%0.195CC..BIsolated β-bridgetrans-86.8155.1172.675.868.3000112.5N673 Q674 F675 C735 L736 Y755D671-N673 VanDerWaalsContact C-N 3.25Å; D671-N673 PolarHBondContact O-N 3.41Å; D671-N673 WeakPolarHBondContact OD1-CA 3.39Å; D671-N673 VanDerWaalsContact OD1-CB 3.24Å; D671-N673 WeakPolarHBondContact OD1-CB 3.35Å; D671-N673 PolarHBondContact OD1-N 3.28Å; D671-Q674 PolarHBondContact O-N 2.96Å; D671-Q674 PolarHBondContact OD1-N 3.43Å; D671-Q674 WeakPolarHBondContact OD2-CG 3.36Å; D671-Q674 PolarHBondContact OD2-NE2 3.27Å; D671-F675 VanDerWaalsContact O-CB 3.29Å; D671-F675 WeakPolarHBondContact O-CB 3.27Å; D671-F675 PolarHBondContact O-N 3.48Å; D671-C735 CarbonylContact C-O 3.46Å; D671-C735 VanDerWaalsContact CA-O 3.31Å; D671-C735 WeakPolarHBondContact CA-O 3.38Å; D671-L736 HydrophobicContact CB-CD2 3.96Å; D671-Y755 PolarHBondContact OD1-OH 2.95Å
672L95.3Very high91.5Very high0 Ų040 Ų400%022%0.215CC..Hα-helixtrans-68.3-24.3-173.7-176.762.9000112.8F675 L676 V709 I713 T732 C735 V737 I743 V799L672-F675 HydrophobicContact CD1-CD1 4.41Å; L672-L676 HydrophobicContact CD1-CD1 3.79Å; L672-L676 HydrophobicContact CD1-CD2 4.29Å; L672-L676 HydrophobicContact CD1-CG 3.7Å; L672-L676 HydrophobicContact CG-CD1 3.91Å; L672-L676 HydrophobicContact CG-CG 4.18Å; L672-L676 WeakPolarHBondContact O-CB 3.39Å; L672-L676 WeakPolarHBondContact O-CG 3.43Å; L672-L676 PolarHBondContact O-N 3.1Å; L672-V709 HydrophobicContact CD1-CG1 3.9Å; L672-V709 HydrophobicContact CD2-CG1 3.74Å; L672-V709 HydrophobicContact CG-CG1 4.45Å; L672-I713 HydrophobicContact CD2-CD1 3.79Å; L672-T732 HydrophobicContact CD2-CG2 4.26Å; L672-T732 HydrophobicContact CG-CG2 4.5Å; L672-C735 HydrophobicContact CB-CB 3.89Å; L672-C735 HydrophobicContact CD2-CB 3.95Å; L672-C735 PolarHBondContact N-O 3.14Å; L672-V737 HydrophobicContact CB-CG2 3.92Å; L672-V737 HydrophobicContact CD1-CG2 3.69Å; L672-V737 HydrophobicContact CG-CG2 4.43Å; L672-I743 HydrophobicContact CD1-CD1 3.9Å; L672-I743 HydrophobicContact CD2-CD1 4.44Å; L672-V799 HydrophobicContact CD2-CG2 4.17Å
673N94.1Very high90.6Very high26 Ų2645 Ų4514%0.13924%0.242CC..Hα-helixtrans-70.7-52.9178.1-172.4-85.4000110.3D671 F675 S677 T732 R733 Y755D671-N673 VanDerWaalsContact C-N 3.25Å; D671-N673 PolarHBondContact O-N 3.41Å; D671-N673 WeakPolarHBondContact OD1-CA 3.39Å; D671-N673 VanDerWaalsContact OD1-CB 3.24Å; D671-N673 WeakPolarHBondContact OD1-CB 3.35Å; D671-N673 PolarHBondContact OD1-N 3.28Å; N673-F675 PolarHBondContact O-N 3.37Å; N673-S677 VanDerWaalsContact O-CB 3.3Å; N673-S677 WeakPolarHBondContact O-CB 3.4Å; N673-S677 PolarHBondContact O-N 2.76Å; N673-S677 PolarHBondContact O-OG 3.19Å; N673-T732 WeakPolarHBondContact CB-OG1 3.35Å; N673-T732 PolarHBondContact ND2-OG1 2.97Å; N673-R733 HydrophobicContact CB-CB 4.44Å; N673-Y755 HydrophobicContact CB-CE1 4.27Å; N673-Y755 VanDerWaalsContact OD1-CE1 3.23Å; N673-Y755 WeakPolarHBondContact OD1-CE1 3.31Å; N673-Y755 PolarHBondContact OD1-OH 2.71Å
674Q91.8Very high89.1Confident97 Ų9751.7 Ų51.745%0.45327%0.271SS..Hα-helixtrans-57.2-50172.8-65.7-175.552.200110.8D671 L676 S677 A678 Y755D671-Q674 PolarHBondContact O-N 2.96Å; D671-Q674 PolarHBondContact OD1-N 3.43Å; D671-Q674 WeakPolarHBondContact OD2-CG 3.36Å; D671-Q674 PolarHBondContact OD2-NE2 3.27Å; Q674-L676 PolarHBondContact O-N 3.43Å; Q674-S677 PolarHBondContact O-N 3.42Å; Q674-S677 PolarHBondContact O-OG 3.24Å; Q674-A678 PolarHBondContact O-N 3.4Å; Q674-Y755 WeakPolarHBondContact CG-OH 3.47Å
675F94.7Very high87.3Confident26 Ų2655.6 Ų55.611%0.11430%0.303CS..Hα-helixtrans-56.9-52-177.5-176-96.5000112.5N669 D671 L672 N673 S677 A678 H679 V737 F741N669-F675 HydrophobicContact CB-CD2 3.73Å; N669-F675 HydrophobicContact CB-CE2 3.79Å; D671-F675 VanDerWaalsContact O-CB 3.29Å; D671-F675 WeakPolarHBondContact O-CB 3.27Å; D671-F675 PolarHBondContact O-N 3.48Å; L672-F675 HydrophobicContact CD1-CD1 4.41Å; N673-F675 PolarHBondContact O-N 3.37Å; F675-S677 PolarHBondContact O-N 3.03Å; F675-A678 PolarHBondContact O-N 3.02Å; F675-H679 AromaticContact CD2-CE1 3.99Å; F675-H679 AromaticContact CE1-CE1 3.56Å; F675-H679 AromaticContact CE1-ND1 3.99Å; F675-H679 AromaticContact CE2-CE1 3.56Å; F675-H679 AromaticContact CZ-CE1 3.32Å; F675-H679 WeakPolarHBondContact CZ-CE1 3.43Å; F675-H679 AromaticContact CZ-NE2 3.79Å; F675-H679 PolarHBondContact O-ND1 3.29Å; F675-V737 HydrophobicContact CB-CG2 3.95Å; F675-V737 HydrophobicContact CD1-CG1 4.17Å; F675-V737 HydrophobicContact CD1-CG2 4.13Å; F675-V737 HydrophobicContact CD2-CB 4.46Å; F675-V737 HydrophobicContact CD2-CG1 4.2Å; F675-V737 HydrophobicContact CE1-CG1 4.15Å; F675-V737 HydrophobicContact CE2-CG1 4.16Å; F675-V737 HydrophobicContact CG-CB 4.32Å; F675-V737 HydrophobicContact CG-CG1 4.19Å; F675-V737 HydrophobicContact CG-CG2 3.99Å; F675-V737 HydrophobicContact CZ-CG1 4.13Å; F675-F741 AromaticContact CE1-CD1 3.67Å; F675-F741 HydrophobicContact CE1-CD1 3.67Å; F675-F741 AromaticContact CE1-CE1 3.64Å; F675-F741 HydrophobicContact CE1-CE1 3.64Å; F675-F741 AromaticContact CZ-CD1 3.82Å; F675-F741 HydrophobicContact CZ-CD1 3.82Å; F675-F741 AromaticContact CZ-CE1 3.6Å; F675-F741 HydrophobicContact CZ-CE1 3.6Å
676L95.3Very high85.6Confident0 Ų057.3 Ų57.30%032%0.321CS..Hα-helixtrans-69.3-33.2179.6-68.9179.6000112.9L672 Q674 A678 H679 I701 L706 V799 L802 C803L672-L676 HydrophobicContact CD1-CD1 3.79Å; L672-L676 HydrophobicContact CD1-CD2 4.29Å; L672-L676 HydrophobicContact CD1-CG 3.7Å; L672-L676 HydrophobicContact CG-CD1 3.91Å; L672-L676 HydrophobicContact CG-CG 4.18Å; L672-L676 WeakPolarHBondContact O-CB 3.39Å; L672-L676 WeakPolarHBondContact O-CG 3.43Å; L672-L676 PolarHBondContact O-N 3.1Å; Q674-L676 PolarHBondContact O-N 3.43Å; L676-A678 PolarHBondContact O-N 3.03Å; L676-H679 PolarHBondContact O-N 3.05Å; L676-I701 HydrophobicContact CD2-CD1 3.74Å; L676-L706 HydrophobicContact CD2-CD2 3.87Å; L676-V799 HydrophobicContact CD1-CB 4.21Å; L676-V799 HydrophobicContact CD1-CG1 4.18Å; L676-V799 HydrophobicContact CD1-CG2 3.98Å; L676-L802 CarbonylContact C-O 3.45Å; L676-L802 VanDerWaalsContact C-O 3.3Å; L676-C803 HydrophobicContact CB-CB 4.34Å
677S92.7Very high83.5Confident52 Ų5263 Ų6336%0.36435%0.35SS..Hα-helixtrans-61.5-30.317877.70000113.1N673 Q674 F675 L802 R804N673-S677 VanDerWaalsContact O-CB 3.3Å; N673-S677 WeakPolarHBondContact O-CB 3.4Å; N673-S677 PolarHBondContact O-N 2.76Å; N673-S677 PolarHBondContact O-OG 3.19Å; Q674-S677 PolarHBondContact O-N 3.42Å; Q674-S677 PolarHBondContact O-OG 3.24Å; F675-S677 PolarHBondContact O-N 3.03Å; S677-L802 WeakPolarHBondContact CA-O 3.49Å; S677-L802 PolarHBondContact N-O 3.26Å; S677-R804 PolarHBondContact O-NH2 2.83Å
678A91.1Very high81.4Confident57 Ų5765.7 Ų65.747%0.47138%0.381SS..Hα-helixtrans-76-21.8174.900000113.4Q674 F675 L676Q674-A678 PolarHBondContact O-N 3.4Å; F675-A678 PolarHBondContact O-N 3.02Å; L676-A678 PolarHBondContact O-N 3.03Å
679H91.9Very high79.4Confident15 Ų1564.7 Ų64.77%0.06939%0.391CS..  trans-89.4156.9-176.5-74.575.3000113.3F675 L676 P699 I701 L802 R804F675-H679 AromaticContact CD2-CE1 3.99Å; F675-H679 AromaticContact CE1-CE1 3.56Å; F675-H679 AromaticContact CE1-ND1 3.99Å; F675-H679 AromaticContact CE2-CE1 3.56Å; F675-H679 AromaticContact CZ-CE1 3.32Å; F675-H679 WeakPolarHBondContact CZ-CE1 3.43Å; F675-H679 AromaticContact CZ-NE2 3.79Å; F675-H679 PolarHBondContact O-ND1 3.29Å; L676-H679 PolarHBondContact O-N 3.05Å; H679-P699 CarbonylContact C-O 3.58Å; H679-P699 VanDerWaalsContact CA-O 3.24Å; H679-P699 WeakPolarHBondContact CA-O 3.49Å; H679-I701 HydrophobicContact CB-CB 4.3Å; H679-I701 HydrophobicContact CB-CG2 3.89Å; H679-L802 HydrophobicContact CB-CD2 4.5Å; H679-L802 WeakPolarHBondContact O-CD2 3.43Å; H679-R804 PolarHBondContact O-NH2 2.93Å
680Q88.8Confident77.8Confident72 Ų7268 Ų6834%0.33642%0.416SS..EExtended strand (participates in β ladder)trans-114.9152.9168.5-66.1177.495.600109.9P699 T700 I701Q680-P699 PolarHBondContact N-O 2.88Å; Q680-T700 CarbonylContact O-C 3.58Å; Q680-T700 VanDerWaalsContact O-CA 3.28Å; Q680-T700 WeakPolarHBondContact O-CA 3.44Å; Q680-I701 PolarHBondContact O-N 3.14Å
681L87.7Confident75.6Confident71 Ų7169.8 Ų69.837%0.37244%0.435SS..EExtended strand (participates in β ladder)trans-69.4135.3174.4-170.772.5000109.3D683 L706 L802 A838L681-D683 PolarHBondContact O-N 2.98Å; L681-L706 HydrophobicContact CD1-CD1 3.7Å; L681-L802 HydrophobicContact CB-CD2 4.47Å; L681-A838 HydrophobicContact CD2-CB 3.87Å
682E84.8Confident73.4Confident91 Ų9177.3 Ų77.343%0.42548%0.475SS..  trans-61.6118.2174.8-178.5-179.1-110.300111.6I701 S702E682-I701 PolarHBondContact N-O 2.88Å; E682-S702 WeakPolarHBondContact OE2-CB 3.49Å
683D72.5Confident71.2Confident109 Ų10980.5 Ų80.558%0.58351%0.508SS*.  trans-94101178.1-170.5-6.5000111.5L681 A685 A686L681-D683 PolarHBondContact O-N 2.98Å; D683-A685 PolarHBondContact O-N 3.49Å; D683-A685 VanDerWaalsContact O-N 3.08Å; D683-A685 VanDerWaalsContact OD1-CB 3.28Å; D683-A685 WeakPolarHBondContact OD1-CB 3.3Å; D683-A685 PolarHBondContact OD1-N 2.81Å; D683-A686 WeakPolarHBondContact O-CB 3.28Å; D683-A686 PolarHBondContact O-N 2.95Å; D683-A686 VanDerWaalsContact O-N 3.08Å
684K62.6Low68.9Low142 Ų14288.8 Ų88.862%0.61755%0.546SS*.THydrogen-bonded Turntrans-62.9-9.1176.7-65.6-173.9177.9-178.50114.1
685A53.7Low66.9Low84 Ų8488.3 Ų88.369%0.69456%0.559SS**THydrogen-bonded Turntrans-83-15.8173.300000113.5D683D683-A685 PolarHBondContact O-N 3.49Å; D683-A685 VanDerWaalsContact O-N 3.08Å; D683-A685 VanDerWaalsContact OD1-CB 3.28Å; D683-A685 WeakPolarHBondContact OD1-CB 3.3Å; D683-A685 PolarHBondContact OD1-N 2.81Å
686A54.2Low64.8Low65 Ų6590.3 Ų90.354%0.53758%0.58SS.*G310 helixtrans-81-18.4-171.500000114.9D683 G688D683-A686 WeakPolarHBondContact O-CB 3.28Å; D683-A686 PolarHBondContact O-N 2.95Å; D683-A686 VanDerWaalsContact O-N 3.08Å; A686-G688 PolarHBondContact O-N 2.8Å
687E47.4Very low63Low185 Ų185100 Ų10086%0.86463%0.626SS**G310 helixtrans-65.9-8.8-173.7-61.9-166.8124.100114.9
688G47.7Very low61.8Low71 Ų7198.8 Ų98.873%0.73262%0.621SS**G310 helixtrans-104.5-3.3-173.900000117A686 P690A686-G688 PolarHBondContact O-N 2.8Å; G688-P690 WeakPolarHBondContact O-CD 3.47Å
689A47.4Very low61.5Low82 Ų8299.3 Ų99.368%0.67862%0.62SS**  trans-116.4102.9-165.900000114.1G691A689-G691 PolarHBondContact O-N 2.83Å
690P57.3Low61.4Low134 Ų134102.5 Ų102.587%0.8764%0.64SS**  trans-78.8103.3167.131.2-30.9000109.8G688G688-P690 WeakPolarHBondContact O-CD 3.47Å
691G45Very low61.5Low70 Ų7099.2 Ų99.272%0.72263%0.625SS**  trans-155.8127.8-178.500000113.6A689A689-G691 PolarHBondContact O-N 2.83Å
692D46Very low61.7Low174 Ų17497.2 Ų97.293%0.9362%0.617SS**  trans-60.5146.7-176.1-57.6-75000114.8
693G48.3Very low62Low68 Ų6894.3 Ų94.370%0.70160%0.602SS**SBendtrans121.996.4157.400000116.1
694Q46.1Very low63Low199 Ų19991.2 Ų91.293%0.9359%0.588SS**  trans53.165155.1-67163.4-10.300115.3A696Q694-A696 PolarHBondContact O-N 3.47Å
695A49.1Very low64.5Low87 Ų8786.9 Ų86.972%0.71957%0.57SS**  trans-49.1135.7170.100000112.2Q697A695-Q697 VanDerWaalsContact O-CG 3.29Å; A695-Q697 WeakPolarHBondContact O-CG 3.4Å; A695-Q697 PolarHBondContact O-N 2.76Å; A695-Q697 VanDerWaalsContact O-N 3.13Å
696A51.5Low66.4Low69 Ų6982.9 Ų82.957%0.5754%0.537SS*.  trans-64.4111.6-179.400000110.7Q694 G698Q694-A696 PolarHBondContact O-N 3.47Å; A696-G698 PolarHBondContact O-N 2.91Å
697Q56.2Low68.4Low204 Ų20479.8 Ų79.895%0.95351%0.512SS*.  trans-78.441.7-162.1-57.5-175.3-23.700115.2A695A695-Q697 VanDerWaalsContact O-CG 3.29Å; A695-Q697 WeakPolarHBondContact O-CG 3.4Å; A695-Q697 PolarHBondContact O-N 2.76Å; A695-Q697 VanDerWaalsContact O-N 3.13Å
698G67.5Low70.7Confident25 Ų2575.4 Ų75.426%0.25849%0.491SS..SBendtrans-119.9147.8176.600000112.2A696A696-G698 PolarHBondContact O-N 2.91Å
699P85.6Confident73Confident69 Ų6972 Ų7245%0.44846%0.456SS..  trans-62.8147.7174.528.7-35.8000111.5H679 Q680H679-P699 CarbonylContact C-O 3.58Å; H679-P699 VanDerWaalsContact CA-O 3.24Å; H679-P699 WeakPolarHBondContact CA-O 3.49Å; Q680-P699 PolarHBondContact N-O 2.88Å
700T89.3Confident75.4Confident82 Ų8268.2 Ų68.250%0.50343%0.425SS..EExtended strand (participates in β ladder)trans-96.2148.9177.346.60000111.9Q680Q680-T700 CarbonylContact O-C 3.58Å; Q680-T700 VanDerWaalsContact O-CA 3.28Å; Q680-T700 WeakPolarHBondContact O-CA 3.44Å
701I92.2Very high77.4Confident3 Ų362.3 Ų62.32%0.01539%0.387CS..EExtended strand (participates in β ladder)trans-128.8132.1171.1-168.2167.8000109.7L676 H679 Q680 E682 M705 L706 F741 L802L676-I701 HydrophobicContact CD2-CD1 3.74Å; H679-I701 HydrophobicContact CB-CB 4.3Å; H679-I701 HydrophobicContact CB-CG2 3.89Å; Q680-I701 PolarHBondContact O-N 3.14Å; E682-I701 PolarHBondContact N-O 2.88Å; I701-M705 HydrophobicContact CD1-CB 4.38Å; I701-M705 HydrophobicContact CD1-CG 4.04Å; I701-M705 HydrophobicContact CG1-CB 3.85Å; I701-M705 HydrophobicContact CG1-CG 3.92Å; I701-L706 HydrophobicContact CD1-CD2 3.83Å; I701-L706 HydrophobicContact CD1-CG 4.46Å; I701-L706 HydrophobicContact CG1-CD2 4.29Å; I701-L706 HydrophobicContact CG1-CG 4.45Å; I701-L706 HydrophobicContact CG2-CD2 4.06Å; I701-L706 HydrophobicContact CG2-CG 4.38Å; I701-F741 HydrophobicContact CD1-CD1 4.01Å; I701-F741 HydrophobicContact CD1-CE1 3.74Å; I701-F741 HydrophobicContact CG1-CE1 4.13Å; I701-L802 HydrophobicContact CG2-CD2 3.9Å
702S91.9Very high79.9Confident28 Ų2859.7 Ų59.720%0.19636%0.356CS..  trans-81.9152.3-178.573.10000111.7E682 M705 L706E682-S702 WeakPolarHBondContact OE2-CB 3.49Å; S702-M705 WeakPolarHBondContact O-CA 3.48Å; S702-M705 WeakPolarHBondContact O-CB 3.38Å; S702-M705 PolarHBondContact O-N 3.37Å; S702-M705 PolarHBondContact OG-N 2.89Å; S702-L706 PolarHBondContact O-N 2.7Å
703Y90.6Very high82.4Confident31 Ų3151.5 Ų51.512%0.12231%0.312CS..Hα-helixtrans-58.2-41.1176.9176.4-100.4000113.6M705 L706 L707 L800 A838 P840 L843 V876Y703-M705 PolarHBondContact O-N 3.27Å; Y703-L706 WeakPolarHBondContact O-CB 3.46Å; Y703-L706 PolarHBondContact O-N 2.77Å; Y703-L706 VanDerWaalsContact O-N 3.15Å; Y703-L707 HydrophobicContact CD1-CD1 4.22Å; Y703-L707 HydrophobicContact CE1-CD1 3.56Å; Y703-L707 HydrophobicContact CE1-CD2 4.47Å; Y703-L707 HydrophobicContact CE1-CG 3.96Å; Y703-L707 HydrophobicContact CE2-CG 4.47Å; Y703-L707 PolarHBondContact O-N 2.82Å; Y703-L800 HydrophobicContact CD2-CD2 4.28Å; Y703-L800 HydrophobicContact CE2-CD2 3.84Å; Y703-A838 WeakPolarHBondContact CD2-O 3.45Å; Y703-A838 WeakPolarHBondContact CE2-O 3.4Å; Y703-P840 HydrophobicContact CE1-CG 4.45Å; Y703-P840 WeakPolarHBondContact OH-CD 3.48Å; Y703-P840 WeakPolarHBondContact OH-CG 3.48Å; Y703-L843 VanDerWaalsContact OH-CD2 3.26Å; Y703-L843 WeakPolarHBondContact OH-CD2 3.23Å; Y703-V876 HydrophobicContact CD1-CG1 3.97Å; Y703-V876 HydrophobicContact CD1-CG2 3.75Å; Y703-V876 HydrophobicContact CE1-CG2 3.56Å
704P92.5Very high84.8Confident44 Ų4448.2 Ų48.229%0.28628%0.279SS..Hα-helixtrans-55.8-34.5168.9-28.737000114.2L707 H708 L873 V876P704-L707 PolarHBondContact O-N 3Å; P704-H708 PolarHBondContact O-N 2.91Å; P704-L873 HydrophobicContact CB-CD1 4.07Å; P704-V876 HydrophobicContact CG-CG1 4.03Å
705M94.1Very high87.2Confident50 Ų5039.3 Ų39.325%0.24624%0.238CC..Hα-helixtrans-72.7-35.9176.8-167.358.771.300112I701 S702 Y703 L707 H708 V709 F741I701-M705 HydrophobicContact CD1-CB 4.38Å; I701-M705 HydrophobicContact CD1-CG 4.04Å; I701-M705 HydrophobicContact CG1-CB 3.85Å; I701-M705 HydrophobicContact CG1-CG 3.92Å; S702-M705 WeakPolarHBondContact O-CA 3.48Å; S702-M705 WeakPolarHBondContact O-CB 3.38Å; S702-M705 PolarHBondContact O-N 3.37Å; S702-M705 PolarHBondContact OG-N 2.89Å; Y703-M705 PolarHBondContact O-N 3.27Å; M705-L707 VanDerWaalsContact C-N 3.33Å; M705-L707 PolarHBondContact O-N 2.87Å; M705-H708 PolarHBondContact O-N 2.94Å; M705-H708 HydrophobicContact SD-CB 4.16Å; M705-V709 WeakPolarHBondContact O-CG2 3.48Å; M705-V709 PolarHBondContact O-N 3.4Å; M705-F741 HydrophobicContact CE-CD2 3.73Å; M705-F741 HydrophobicContact CE-CE2 4.12Å; M705-F741 HydrophobicContact CE-CG 4.32Å; M705-F741 HydrophobicContact CG-CB 4.21Å; M705-F741 HydrophobicContact CG-CD1 3.8Å; M705-F741 HydrophobicContact CG-CD2 3.94Å; M705-F741 HydrophobicContact CG-CE1 4.11Å; M705-F741 HydrophobicContact CG-CE2 4.25Å; M705-F741 HydrophobicContact CG-CG 3.72Å; M705-F741 HydrophobicContact CG-CZ 4.33Å; M705-F741 HydrophobicContact SD-CB 3.63Å; M705-F741 HydrophobicContact SD-CD1 4.31Å; M705-F741 HydrophobicContact SD-CD2 3.66Å; M705-F741 HydrophobicContact SD-CE2 4.41Å; M705-F741 HydrophobicContact SD-CG 3.62Å
706L95.3Very high89.5Confident0 Ų035.1 Ų35.10%020%0.204CC..Hα-helixtrans-62.1-39.4170.6-64.8174.7000111.8L676 L681 I701 S702 Y703 A710 V799 L800 L802L676-L706 HydrophobicContact CD2-CD2 3.87Å; L681-L706 HydrophobicContact CD1-CD1 3.7Å; I701-L706 HydrophobicContact CD1-CD2 3.83Å; I701-L706 HydrophobicContact CD1-CG 4.46Å; I701-L706 HydrophobicContact CG1-CD2 4.29Å; I701-L706 HydrophobicContact CG1-CG 4.45Å; I701-L706 HydrophobicContact CG2-CD2 4.06Å; I701-L706 HydrophobicContact CG2-CG 4.38Å; S702-L706 PolarHBondContact O-N 2.7Å; Y703-L706 WeakPolarHBondContact O-CB 3.46Å; Y703-L706 PolarHBondContact O-N 2.77Å; Y703-L706 VanDerWaalsContact O-N 3.15Å; L706-A710 WeakPolarHBondContact O-CB 3.39Å; L706-A710 PolarHBondContact O-N 3.22Å; L706-V799 HydrophobicContact CB-CG1 4.14Å; L706-V799 HydrophobicContact CD2-CG1 3.92Å; L706-L800 HydrophobicContact CB-CD2 4.16Å; L706-L800 HydrophobicContact CD1-CD2 4.33Å; L706-L802 HydrophobicContact CD1-CD1 4.12Å
707L95.1Very high91.7Very high1 Ų131.9 Ų31.91%0.00518%0.177CC..Hα-helixtrans-64-41.1171.3-69.6-179.7000112.2Y703 P704 M705 A710 A711 L843 L868 A872 L873 V876Y703-L707 HydrophobicContact CD1-CD1 4.22Å; Y703-L707 HydrophobicContact CE1-CD1 3.56Å; Y703-L707 HydrophobicContact CE1-CD2 4.47Å; Y703-L707 HydrophobicContact CE1-CG 3.96Å; Y703-L707 HydrophobicContact CE2-CG 4.47Å; Y703-L707 PolarHBondContact O-N 2.82Å; P704-L707 PolarHBondContact O-N 3Å; M705-L707 VanDerWaalsContact C-N 3.33Å; M705-L707 PolarHBondContact O-N 2.87Å; L707-A710 PolarHBondContact O-N 2.94Å; L707-A711 WeakPolarHBondContact O-CB 3.32Å; L707-A711 PolarHBondContact O-N 2.75Å; L707-L843 HydrophobicContact CD2-CD2 3.8Å; L707-L868 HydrophobicContact CD2-CD2 3.84Å; L707-A872 HydrophobicContact CD1-CB 3.87Å; L707-A872 HydrophobicContact CD2-CB 4.1Å; L707-L873 HydrophobicContact CB-CD1 4.44Å; L707-L873 HydrophobicContact CD1-CD1 4.06Å; L707-V876 HydrophobicContact CD1-CG2 4.25Å
708H95.3Very high93.7Very high92 Ų9226 Ų2643%0.42615%0.146SC..Hα-helixtrans-64.1-43177.2-175.761000112.5P704 M705 A711 Q712P704-H708 PolarHBondContact O-N 2.91Å; M705-H708 PolarHBondContact O-N 2.94Å; M705-H708 HydrophobicContact SD-CB 4.16Å; H708-A711 PolarHBondContact O-N 3.13Å; H708-Q712 PolarHBondContact CD2-NE2 3.47Å; H708-Q712 PolarHBondContact NE2-NE2 2.65Å; H708-Q712 WeakPolarHBondContact O-CG 3.33Å; H708-Q712 PolarHBondContact O-N 3.41Å; H708-Q712 VanDerWaalsContact O-N 3.08Å; H708-Q712 PolarHBondContact O-NE2 2.92Å
709V97.6Very high95Very high1 Ų126.9 Ų26.91%0.00614%0.142CC..Hα-helixtrans-56.9-48.9171.4163.10000110.7L672 M705 Q712 I713 F741 I743 V799L672-V709 HydrophobicContact CD1-CG1 3.9Å; L672-V709 HydrophobicContact CD2-CG1 3.74Å; L672-V709 HydrophobicContact CG-CG1 4.45Å; M705-V709 WeakPolarHBondContact O-CG2 3.48Å; M705-V709 PolarHBondContact O-N 3.4Å; V709-Q712 PolarHBondContact O-N 2.97Å; V709-I713 HydrophobicContact CG1-CD1 4.44Å; V709-I713 WeakPolarHBondContact O-CG1 3.36Å; V709-I713 PolarHBondContact O-N 2.71Å; V709-F741 HydrophobicContact CG2-CB 4.44Å; V709-I743 HydrophobicContact CB-CG1 4.29Å; V709-I743 HydrophobicContact CG1-CD1 4.14Å; V709-I743 HydrophobicContact CG1-CG1 4.05Å; V709-I743 HydrophobicContact CG2-CD1 4.14Å; V709-I743 HydrophobicContact CG2-CG1 4.17Å; V709-V799 HydrophobicContact CG1-CG1 4.23Å; V709-V799 HydrophobicContact CG1-CG2 4.28Å
710A97.8Very high95.3Very high2 Ų223.7 Ų23.72%0.01712%0.121CC..Hα-helixtrans-65.6-39.717900000113.6L706 L707 Q712 I713 A714 L796 L868L706-A710 WeakPolarHBondContact O-CB 3.39Å; L706-A710 PolarHBondContact O-N 3.22Å; L707-A710 PolarHBondContact O-N 2.94Å; A710-Q712 VanDerWaalsContact C-N 3.33Å; A710-Q712 PolarHBondContact O-N 3.14Å; A710-I713 PolarHBondContact O-N 2.91Å; A710-A714 PolarHBondContact O-N 3.19Å; A710-L796 HydrophobicContact CB-CD1 3.45Å; A710-L796 VanDerWaalsContact CB-CD1 3.45Å; A710-L868 HydrophobicContact CB-CD1 4.02Å; A710-L868 HydrophobicContact CB-CD2 4.16Å
711A97.6Very high95.3Very high9 Ų921 Ų217%0.07411%0.107CC..Hα-helixtrans-63.8-37.6177.400000112L707 H708 A714 S715 L868 A869L707-A711 WeakPolarHBondContact O-CB 3.32Å; L707-A711 PolarHBondContact O-N 2.75Å; H708-A711 PolarHBondContact O-N 3.13Å; A711-A714 PolarHBondContact O-N 2.75Å; A711-S715 PolarHBondContact O-N 2.72Å; A711-L868 HydrophobicContact CB-CB 3.92Å; A711-A869 HydrophobicContact CB-CB 4.44Å
712Q98.3Very high95.1Very high16 Ų1625.7 Ų25.78%0.07514%0.136CC..Hα-helixtrans-63.7-43.1173.3-75.8-178.286.400112.3N646 H708 V709 A710 A714 S715 G716 F741 I743N646-Q712 VanDerWaalsContact CB-O 3.29Å; N646-Q712 WeakPolarHBondContact CB-O 3.39Å; N646-Q712 WeakPolarHBondContact ND2-CB 3.32Å; N646-Q712 WeakPolarHBondContact ND2-CG 3.36Å; N646-Q712 PolarHBondContact ND2-OE1 3.15Å; N646-Q712 VanDerWaalsContact ND2-OE1 3.09Å; H708-Q712 PolarHBondContact CD2-NE2 3.47Å; H708-Q712 PolarHBondContact NE2-NE2 2.65Å; H708-Q712 WeakPolarHBondContact O-CG 3.33Å; H708-Q712 PolarHBondContact O-N 3.41Å; H708-Q712 VanDerWaalsContact O-N 3.08Å; H708-Q712 PolarHBondContact O-NE2 2.92Å; V709-Q712 PolarHBondContact O-N 2.97Å; A710-Q712 VanDerWaalsContact C-N 3.33Å; A710-Q712 PolarHBondContact O-N 3.14Å; Q712-A714 VanDerWaalsContact C-N 3.34Å; Q712-A714 PolarHBondContact O-N 2.83Å; Q712-S715 VanDerWaalsContact O-CB 3.27Å; Q712-S715 WeakPolarHBondContact O-CB 3.49Å; Q712-S715 PolarHBondContact O-N 3.47Å; Q712-S715 VanDerWaalsContact O-N 3.13Å; Q712-G716 PolarHBondContact O-N 3.25Å; Q712-F741 PolarHBondContact NE2-O 2.92Å; Q712-I743 HydrophobicContact CB-CB 3.99Å; Q712-I743 HydrophobicContact CB-CG1 4.31Å
713I98.4Very high94.8Very high1 Ų126.3 Ų26.31%0.00514%0.137CC..Hα-helixtrans-62.2-43.4174.2-60.1167.7000110.1L672 V709 A710 S715 G716 M717 L730 I743 I745 F792 T795L672-I713 HydrophobicContact CD2-CD1 3.79Å; V709-I713 HydrophobicContact CG1-CD1 4.44Å; V709-I713 WeakPolarHBondContact O-CG1 3.36Å; V709-I713 PolarHBondContact O-N 2.71Å; A710-I713 PolarHBondContact O-N 2.91Å; I713-S715 VanDerWaalsContact C-N 3.26Å; I713-S715 PolarHBondContact O-N 3.07Å; I713-G716 PolarHBondContact O-N 3.35Å; I713-M717 HydrophobicContact CG2-CG 4.43Å; I713-M717 WeakPolarHBondContact O-CB 3.41Å; I713-M717 WeakPolarHBondContact O-CG 3.31Å; I713-M717 PolarHBondContact O-N 3.16Å; I713-L730 HydrophobicContact CG2-CD1 4.14Å; I713-I743 HydrophobicContact CG1-CG2 3.81Å; I713-I745 HydrophobicContact CG2-CD1 3.97Å; I713-I745 HydrophobicContact CG2-CG1 4.45Å; I713-F792 HydrophobicContact CB-CE2 4.04Å; I713-F792 HydrophobicContact CG2-CD2 3.85Å; I713-F792 HydrophobicContact CG2-CE2 3.8Å; I713-T795 HydrophobicContact CD1-CG2 4.1Å
714A98.3Very high94.4Very high0 Ų030 Ų300%016%0.159CC..Hα-helixtrans-62.9-31.317500000112.8A710 A711 Q712 R718 F792 L864 H865 L868A710-A714 PolarHBondContact O-N 3.19Å; A711-A714 PolarHBondContact O-N 2.75Å; Q712-A714 VanDerWaalsContact C-N 3.34Å; Q712-A714 PolarHBondContact O-N 2.83Å; A714-R718 WeakPolarHBondContact O-CB 3.48Å; A714-R718 PolarHBondContact O-N 2.88Å; A714-F792 HydrophobicContact CB-CE2 3.9Å; A714-F792 HydrophobicContact CB-CZ 3.84Å; A714-L864 HydrophobicContact CB-CB 4.41Å; A714-H865 HydrophobicContact CB-CB 3.93Å; A714-L868 HydrophobicContact CB-CD1 4.24Å
715S98.1Very high93.9Very high11 Ų1128.4 Ų28.48%0.07715%0.147CC..Hα-helixtrans-65.4-51.9173.9-173.30000111.9N646 A711 Q712 I713 M717 R718 Y719N646-S715 WeakPolarHBondContact OD1-CB 3.49Å; N646-S715 PolarHBondContact OD1-OG 3.27Å; A711-S715 PolarHBondContact O-N 2.72Å; Q712-S715 VanDerWaalsContact O-CB 3.27Å; Q712-S715 WeakPolarHBondContact O-CB 3.49Å; Q712-S715 PolarHBondContact O-N 3.47Å; Q712-S715 VanDerWaalsContact O-N 3.13Å; I713-S715 VanDerWaalsContact C-N 3.26Å; I713-S715 PolarHBondContact O-N 3.07Å; S715-M717 PolarHBondContact O-N 2.79Å; S715-R718 WeakPolarHBondContact O-CB 3.41Å; S715-R718 PolarHBondContact O-N 3.48Å; S715-R718 PolarHBondContact OG-NH2 3.34Å; S715-Y719 PolarHBondContact O-N 3.03Å
716G96.7Very high93.5Very high0 Ų026.7 Ų26.70%014%0.14CC..Hα-helixtrans-61.6-44.5178.400000111.8Q712 I713 R718 Y719 L720Q712-G716 PolarHBondContact O-N 3.25Å; I713-G716 PolarHBondContact O-N 3.35Å; G716-R718 PolarHBondContact O-N 3.29Å; G716-Y719 WeakPolarHBondContact O-CB 3.37Å; G716-Y719 PolarHBondContact O-N 3.27Å; G716-Y719 VanDerWaalsContact O-N 3.09Å; G716-L720 PolarHBondContact O-N 2.87Å
717M97.6Very high93.3Very high1 Ų126.7 Ų26.71%0.00514%0.14CC..Hα-helixtrans-67.3-33177-68.3-54.4-58.800113.5I713 S715 Y719 L720 A721 H727 L730 I745 D788 F861I713-M717 HydrophobicContact CG2-CG 4.43Å; I713-M717 WeakPolarHBondContact O-CB 3.41Å; I713-M717 WeakPolarHBondContact O-CG 3.31Å; I713-M717 PolarHBondContact O-N 3.16Å; S715-M717 PolarHBondContact O-N 2.79Å; M717-Y719 VanDerWaalsContact C-N 3.32Å; M717-L720 HydrophobicContact CE-CD1 4.45Å; M717-L720 PolarHBondContact O-N 2.78Å; M717-L720 HydrophobicContact SD-CD1 3.92Å; M717-A721 VanDerWaalsContact O-CB 3.3Å; M717-A721 WeakPolarHBondContact O-CB 3.46Å; M717-A721 PolarHBondContact O-N 2.92Å; M717-H727 HydrophobicContact CE-CB 3.9Å; M717-H727 HydrophobicContact SD-CB 4.31Å; M717-L730 HydrophobicContact CE-CD2 4.08Å; M717-L730 HydrophobicContact CG-CD1 4.22Å; M717-L730 HydrophobicContact CG-CD2 3.66Å; M717-L730 HydrophobicContact SD-CD1 3.87Å; M717-L730 HydrophobicContact SD-CD2 3.84Å; M717-L730 HydrophobicContact SD-CG 4.36Å; M717-I745 HydrophobicContact CG-CD1 3.63Å; M717-I745 HydrophobicContact SD-CD1 3.73Å; M717-D788 HydrophobicContact CE-CB 3.74Å; M717-F861 HydrophobicContact CB-CD1 3.51Å; M717-F861 HydrophobicContact CB-CD2 3.99Å; M717-F861 HydrophobicContact CB-CE1 3.37Å; M717-F861 HydrophobicContact CB-CE2 3.87Å; M717-F861 HydrophobicContact CB-CG 3.82Å; M717-F861 HydrophobicContact CB-CZ 3.57Å; M717-F861 HydrophobicContact CE-CE2 4.06Å; M717-F861 HydrophobicContact CE-CZ 3.87Å; M717-F861 HydrophobicContact CG-CD1 4.49Å; M717-F861 HydrophobicContact CG-CE1 3.94Å; M717-F861 HydrophobicContact CG-CZ 4.04Å
718R97.2Very high92.9Very high79 Ų7929.5 Ų29.530%0.29815%0.15SC..Hα-helixtrans-60-41.9168.4172.4-172.362.6-158.9-9.9111.1A714 S715 G716 A721 T722 F861 H865A714-R718 WeakPolarHBondContact O-CB 3.48Å; A714-R718 PolarHBondContact O-N 2.88Å; S715-R718 WeakPolarHBondContact O-CB 3.41Å; S715-R718 PolarHBondContact O-N 3.48Å; S715-R718 PolarHBondContact OG-NH2 3.34Å; G716-R718 PolarHBondContact O-N 3.29Å; R718-A721 PolarHBondContact O-N 3.18Å; R718-T722 PolarHBondContact O-N 3.32Å; R718-F861 HydrophobicContact CB-CB 3.8Å; R718-H865 PolarHBondContact NH1-CD2 2.86Å; R718-H865 VanDerWaalsContact NH1-CD2 3.27Å; R718-H865 PolarHBondContact NH1-CE1 3.46Å; R718-H865 VanDerWaalsContact NH1-CG 3.28Å; R718-H865 PolarHBondContact NH1-ND1 3.02Å; R718-H865 PolarHBondContact NH1-NE2 2.98Å; R718-H865 PolarHBondContact NH2-CD2 2.65Å; R718-H865 PolarHBondContact NH2-NE2 2.58Å
719Y95.3Very high92.7Very high45 Ų4525.2 Ų25.218%0.17613%0.13CC..Hα-helixtrans-66-44.3176.9173.4-92.5000112.4R641 L642 K643 D644 I647 S715 G716 M717 A721 T722 L723R641-Y719 PolarHBondContact O-OH 3.43Å; L642-Y719 HydrophobicContact CD2-CE1 4.17Å; K643-Y719 PolarHBondContact N-OH 3.11Å; D644-Y719 HydrophobicContact CB-CD1 3.61Å; D644-Y719 HydrophobicContact CB-CD2 3.78Å; D644-Y719 HydrophobicContact CB-CE1 3.94Å; D644-Y719 HydrophobicContact CB-CE2 4.09Å; D644-Y719 HydrophobicContact CB-CG 3.52Å; I647-Y719 HydrophobicContact CG1-CD1 4.08Å; S715-Y719 PolarHBondContact O-N 3.03Å; G716-Y719 WeakPolarHBondContact O-CB 3.37Å; G716-Y719 PolarHBondContact O-N 3.27Å; G716-Y719 VanDerWaalsContact O-N 3.09Å; M717-Y719 VanDerWaalsContact C-N 3.32Å; Y719-A721 VanDerWaalsContact C-N 3.28Å; Y719-A721 PolarHBondContact O-N 3.12Å; Y719-T722 PolarHBondContact O-N 2.96Å; Y719-T722 PolarHBondContact O-OG1 3.47Å; Y719-L723 HydrophobicContact CD1-CD1 4.32Å; Y719-L723 HydrophobicContact CE1-CD1 3.62Å; Y719-L723 HydrophobicContact CE1-CG 4.4Å; Y719-L723 PolarHBondContact O-N 2.9Å
720L91.3Very high92.6Very high2 Ų225.1 Ų25.11%0.0113%0.13CC..Hα-helixtrans-60.1-41.2173.7-62.4-174000111.3L642 I647 G716 M717 T722 L723 N724 F725 H727L642-L720 HydrophobicContact CD1-CD2 4.5Å; L642-L720 HydrophobicContact CD2-CD2 3.74Å; I647-L720 HydrophobicContact CD1-CD1 4.03Å; I647-L720 HydrophobicContact CD1-CD2 4.05Å; I647-L720 HydrophobicContact CD1-CG 3.89Å; I647-L720 HydrophobicContact CG1-CD2 4.28Å; G716-L720 PolarHBondContact O-N 2.87Å; M717-L720 HydrophobicContact CE-CD1 4.45Å; M717-L720 PolarHBondContact O-N 2.78Å; M717-L720 HydrophobicContact SD-CD1 3.92Å; L720-T722 PolarHBondContact O-N 3.06Å; L720-L723 WeakPolarHBondContact O-CB 3.39Å; L720-L723 PolarHBondContact O-N 3.47Å; L720-N724 PolarHBondContact O-N 3.05Å; L720-F725 CarbonylContact C-O 3.55Å; L720-F725 HydrophobicContact CB-CB 4.49Å; L720-F725 HydrophobicContact CB-CD1 4.05Å; L720-F725 HydrophobicContact CD1-CD1 4.05Å; L720-F725 HydrophobicContact CD1-CE1 4.16Å; L720-F725 HydrophobicContact CD2-CD1 3.72Å; L720-F725 HydrophobicContact CD2-CE1 3.93Å; L720-F725 HydrophobicContact CG-CD1 4.13Å; L720-F725 WeakPolarHBondContact O-CB 3.47Å; L720-F725 PolarHBondContact O-N 2.74Å; L720-H727 HydrophobicContact CD1-CB 4.46Å
721A89.7Confident92.4Very high26 Ų2625 Ų2522%0.21513%0.129CC..Hα-helixtrans-61.8-38.6176.300000113.8M717 R718 Y719 L723 N724 T785 F861M717-A721 VanDerWaalsContact O-CB 3.3Å; M717-A721 WeakPolarHBondContact O-CB 3.46Å; M717-A721 PolarHBondContact O-N 2.92Å; R718-A721 PolarHBondContact O-N 3.18Å; Y719-A721 VanDerWaalsContact C-N 3.28Å; Y719-A721 PolarHBondContact O-N 3.12Å; A721-L723 VanDerWaalsContact C-N 3.27Å; A721-L723 PolarHBondContact O-N 2.85Å; A721-N724 WeakPolarHBondContact O-CA 3.39Å; A721-N724 PolarHBondContact O-N 3.24Å; A721-T785 HydrophobicContact CB-CG2 3.59Å; A721-F861 HydrophobicContact CB-CD2 4.19Å
722T89.4Confident92.3Very high101 Ų10124.6 Ų24.662%0.6213%0.126SC*.Hα-helixtrans-69.5-25.2176.559.40000112.8R718 Y719 L720 N724R718-T722 PolarHBondContact O-N 3.32Å; Y719-T722 PolarHBondContact O-N 2.96Å; Y719-T722 PolarHBondContact O-OG1 3.47Å; L720-T722 PolarHBondContact O-N 3.06Å; T722-N724 PolarHBondContact O-N 3.5Å
723L85.1Confident92.1Very high41 Ų4124.2 Ų24.222%0.21512%0.123CC..THydrogen-bonded Turntrans-76.1-7.9169.2-62.1-178.4000113.2P552 L642 Y719 L720 A721 F725P552-L723 WeakPolarHBondContact CG-O 3.25Å; L642-L723 HydrophobicContact CD2-CD1 3.86Å; Y719-L723 HydrophobicContact CD1-CD1 4.32Å; Y719-L723 HydrophobicContact CE1-CD1 3.62Å; Y719-L723 HydrophobicContact CE1-CG 4.4Å; Y719-L723 PolarHBondContact O-N 2.9Å; L720-L723 WeakPolarHBondContact O-CB 3.39Å; L720-L723 PolarHBondContact O-N 3.47Å; A721-L723 VanDerWaalsContact C-N 3.27Å; A721-L723 PolarHBondContact O-N 2.85Å; L723-F725 VanDerWaalsContact C-N 3.28Å; L723-F725 HydrophobicContact CB-CB 4.09Å
724N81.6Confident91.8Very high109 Ų10924.5 Ų24.558%0.58313%0.125SC*.THydrogen-bonded Turntrans65.922.9-166.8-57.2-89.8000114.2P552 L720 A721 T722P552-N724 HydrophobicContact CB-CB 3.66Å; P552-N724 WeakPolarHBondContact CB-O 3.03Å; P552-N724 HydrophobicContact CG-CB 3.97Å; P552-N724 WeakPolarHBondContact CG-O 3.37Å; L720-N724 PolarHBondContact O-N 3.05Å; A721-N724 WeakPolarHBondContact O-CA 3.39Å; A721-N724 PolarHBondContact O-N 3.24Å; T722-N724 PolarHBondContact O-N 3.5Å
725F83.2Confident91.6Very high10 Ų1024.5 Ų24.54%0.04413%0.125CC..  trans-96.1132.3-171.4-177.9-87.5000110.8Y549 A550 I638 L642 L720 L723Y549-F725 VanDerWaalsContact CB-CZ 3.4Å; Y549-F725 HydrophobicContact CD1-CD1 4.5Å; Y549-F725 AromaticContact CD1-CE1 3.32Å; Y549-F725 HydrophobicContact CD1-CE1 3.32Å; Y549-F725 AromaticContact CD1-CZ 3.46Å; Y549-F725 HydrophobicContact CD1-CZ 3.46Å; Y549-F725 VanDerWaalsContact CD1-CZ 3.46Å; Y549-F725 HydrophobicContact CD2-CE1 4.41Å; Y549-F725 AromaticContact CD2-CZ 3.75Å; Y549-F725 HydrophobicContact CD2-CZ 3.75Å; Y549-F725 AromaticContact CE1-CE1 3.76Å; Y549-F725 HydrophobicContact CE1-CE1 3.76Å; Y549-F725 HydrophobicContact CE1-CZ 4.06Å; Y549-F725 HydrophobicContact CE2-CZ 4.29Å; Y549-F725 AromaticContact CG-CE1 3.69Å; Y549-F725 HydrophobicContact CG-CE1 3.69Å; Y549-F725 HydrophobicContact CG-CE2 4.26Å; Y549-F725 AromaticContact CG-CZ 3.27Å; Y549-F725 HydrophobicContact CG-CZ 3.27Å; A550-F725 VanDerWaalsContact O-CD2 3.26Å; A550-F725 WeakPolarHBondContact O-CD2 3.5Å; I638-F725 HydrophobicContact CB-CE2 4.49Å; I638-F725 HydrophobicContact CD1-CE2 4.46Å; I638-F725 HydrophobicContact CG1-CE2 4.32Å; I638-F725 HydrophobicContact CG2-CE2 3.48Å; I638-F725 VanDerWaalsContact CG2-CE2 3.48Å; I638-F725 HydrophobicContact CG2-CZ 3.43Å; I638-F725 VanDerWaalsContact CG2-CZ 3.43Å; L642-F725 HydrophobicContact CD1-CZ 4.46Å; L720-F725 CarbonylContact C-O 3.55Å; L720-F725 HydrophobicContact CB-CB 4.49Å; L720-F725 HydrophobicContact CB-CD1 4.05Å; L720-F725 HydrophobicContact CD1-CD1 4.05Å; L720-F725 HydrophobicContact CD1-CE1 4.16Å; L720-F725 HydrophobicContact CD2-CD1 3.72Å; L720-F725 HydrophobicContact CD2-CE1 3.93Å; L720-F725 HydrophobicContact CG-CD1 4.13Å; L720-F725 WeakPolarHBondContact O-CB 3.47Å; L720-F725 PolarHBondContact O-N 2.74Å; L723-F725 VanDerWaalsContact C-N 3.28Å; L723-F725 HydrophobicContact CB-CB 4.09Å
726V85.9Confident91.4Very high14 Ų1425.5 Ų25.59%0.08513%0.13CC..BIsolated β-bridgetrans-111.7131.3-173.3-174.10000109.9A550 R728 F783 D788A550-V726 HydrophobicContact CB-CB 3.92Å; A550-V726 PolarHBondContact N-O 3.34Å; V726-R728 HydrophobicContact CG1-CG 4.01Å; V726-F783 HydrophobicContact CG1-CB 4.39Å; V726-D788 VanDerWaalsContact CA-OD2 3.3Å; V726-D788 WeakPolarHBondContact CA-OD2 3.43Å; V726-D788 WeakPolarHBondContact CG1-OD1 3.32Å; V726-D788 WeakPolarHBondContact CG1-OD2 3.41Å
727H89.3Confident91.3Very high0 Ų025.5 Ų25.50%013%0.13CC..  trans-87.1-33.5-172.7-163.7-40.1000113.7T548 Y549 M717 L720 D729 I745 D788T548-H727 WeakPolarHBondContact CG2-O 3.34Å; Y549-H727 AromaticContact CE1-CE1 3.94Å; Y549-H727 AromaticContact CE1-NE2 3.9Å; M717-H727 HydrophobicContact CE-CB 3.9Å; M717-H727 HydrophobicContact SD-CB 4.31Å; L720-H727 HydrophobicContact CD1-CB 4.46Å; H727-D729 PolarHBondContact O-N 3.29Å; H727-I745 WeakPolarHBondContact NE2-CG2 3.48Å; H727-D788 PolarHBondContact N-OD1 3.04Å; H727-D788 PolarHBondContact N-OD2 3.25Å
728R88.4Confident91.1Very high59 Ų5925.7 Ų25.722%0.22313%0.132CC..SBendtrans64.9-20.8175.8-49.7-169.6171.1173.8-6.4118.2Q541 T548 V726 F783 D788Q541-R728 PolarHBondContact O-NH1 3.03Å; T548-R728 HydrophobicContact CG2-CB 3.85Å; T548-R728 WeakPolarHBondContact O-CD 3.43Å; T548-R728 WeakPolarHBondContact O-CG 3.46Å; V726-R728 HydrophobicContact CG1-CG 4.01Å; R728-F783 HydrophobicContact CB-CD1 3.63Å; R728-F783 HydrophobicContact CB-CE1 3.9Å; R728-F783 HydrophobicContact CB-CG 4.33Å; R728-F783 HydrophobicContact CG-CB 3.9Å; R728-F783 HydrophobicContact CG-CD1 3.61Å; R728-F783 HydrophobicContact CG-CE1 4.31Å; R728-F783 HydrophobicContact CG-CG 3.82Å; R728-D788 PolarHBondContact N-OD1 3.4Å
729D90Very high90.7Very high2 Ų225.2 Ų25.21%0.01113%0.133CC..  trans-141.657.1179-174.924000109.7T548 H727 R733 N734 Y759 P769T548-D729 HydrophobicContact CG2-CB 3.31Å; H727-D729 PolarHBondContact O-N 3.29Å; D729-R733 IonicContact OD1-CZ 3.02Å; D729-R733 IonicContact OD1-NE 3.3Å; D729-R733 IonicContact OD1-NH2 3.17Å; D729-R733 PolarHBondContact OD1-NH2 3.34Å; D729-N734 PolarHBondContact O-ND2 2.7Å; D729-N734 PolarHBondContact OD2-ND2 3.35Å; D729-Y759 PolarHBondContact OD1-OH 3.16Å; D729-Y759 WeakPolarHBondContact OD2-CE1 3.37Å; D729-Y759 PolarHBondContact OD2-OH 3.32Å; D729-P769 HydrophobicContact CB-CG 4.17Å; D729-P769 WeakPolarHBondContact OD1-CB 3.31Å; D729-P769 WeakPolarHBondContact OD1-CG 3.34Å
730L95Very high90.5Very high0 Ų029.4 Ų29.40%016%0.158CC..  trans-80.9120.1171.8179.667.7000109.3I713 M717 I745 A791 F792 T795I713-L730 HydrophobicContact CG2-CD1 4.14Å; M717-L730 HydrophobicContact CE-CD2 4.08Å; M717-L730 HydrophobicContact CG-CD1 4.22Å; M717-L730 HydrophobicContact CG-CD2 3.66Å; M717-L730 HydrophobicContact SD-CD1 3.87Å; M717-L730 HydrophobicContact SD-CD2 3.84Å; M717-L730 HydrophobicContact SD-CG 4.36Å; L730-I745 HydrophobicContact CD1-CD1 4.27Å; L730-I745 HydrophobicContact CD1-CG2 3.99Å; L730-A791 HydrophobicContact CB-CB 4.09Å; L730-F792 HydrophobicContact CD2-CB 3.78Å; L730-F792 HydrophobicContact CD2-CD2 4.21Å; L730-T795 PolarHBondContact O-OG1 2.87Å
731A95.3Very high90.6Very high0 Ų031.9 Ų31.90%017%0.169CC..SBendtrans-159.8166.6179.400000109.7R733 N734 W772A731-R733 VanDerWaalsContact C-N 3.31Å; A731-R733 HydrophobicContact CB-CG 3.84Å; A731-R733 VanDerWaalsContact CB-CZ 3.44Å; A731-R733 PolarHBondContact O-N 2.81Å; A731-N734 PolarHBondContact O-N 2.75Å; A731-W772 HydrophobicContact CB-CD2 4.26Å; A731-W772 HydrophobicContact CB-CG 4.24Å; A731-W772 HydrophobicContact CB-CZ2 4.39Å; A731-W772 VanDerWaalsContact CB-NE1 3.34Å
732T95.5Very high90.9Very high0 Ų033.3 Ų33.30%018%0.175CC..G310 helixtrans-61.1-3717960.10000113.3L672 N673 N734 C735 T795 E798 V799L672-T732 HydrophobicContact CD2-CG2 4.26Å; L672-T732 HydrophobicContact CG-CG2 4.5Å; N673-T732 WeakPolarHBondContact CB-OG1 3.35Å; N673-T732 PolarHBondContact ND2-OG1 2.97Å; T732-N734 PolarHBondContact O-N 2.56Å; T732-C735 PolarHBondContact O-N 3.29Å; T732-T795 HydrophobicContact CG2-CG2 4.05Å; T732-E798 WeakPolarHBondContact CB-OE1 3.16Å; T732-E798 HydrophobicContact CG2-CB 3.51Å; T732-E798 HydrophobicContact CG2-CG 4.23Å; T732-E798 PolarHBondContact N-OE2 2.81Å; T732-E798 VanDerWaalsContact N-OE2 3.13Å; T732-E798 PolarHBondContact OG1-OE1 3.43Å; T732-V799 HydrophobicContact CG2-CG2 3.99Å
733R92.3Very high91.3Very high7 Ų728.5 Ų28.53%0.02615%0.146CC..G310 helixtrans-58.3-15.5173.361.9174.3178.8-81.2-15.3115.2N673 D729 A731 Y755 D758 Y759N673-R733 HydrophobicContact CB-CB 4.44Å; D729-R733 IonicContact OD1-CZ 3.02Å; D729-R733 IonicContact OD1-NE 3.3Å; D729-R733 IonicContact OD1-NH2 3.17Å; D729-R733 PolarHBondContact OD1-NH2 3.34Å; A731-R733 VanDerWaalsContact C-N 3.31Å; A731-R733 HydrophobicContact CB-CG 3.84Å; A731-R733 VanDerWaalsContact CB-CZ 3.44Å; A731-R733 PolarHBondContact O-N 2.81Å; R733-Y755 HydrophobicContact CB-CD1 4.3Å; R733-Y755 HydrophobicContact CB-CD2 3.57Å; R733-Y755 HydrophobicContact CB-CE1 4.34Å; R733-Y755 HydrophobicContact CB-CE2 3.61Å; R733-Y755 HydrophobicContact CB-CG 3.94Å; R733-Y755 HydrophobicContact CG-CD2 4.39Å; R733-Y755 HydrophobicContact CG-CG 4.48Å; R733-D758 IonicContact CZ-OD2 2.63Å; R733-D758 IonicContact NE-OD2 2.7Å; R733-D758 VanDerWaalsContact NH1-CG 3.33Å; R733-D758 IonicContact NH1-OD2 2.73Å; R733-D758 PolarHBondContact NH1-OD2 3.13Å; R733-Y759 PolarHBondContact NE-OH 2.94Å
734N92.3Very high91.8Very high7 Ų727.6 Ų27.64%0.03714%0.14CC..G310 helixtrans-111.814.1178.6-72.1-18000111.9D729 A731 T732 A746 S751D729-N734 PolarHBondContact O-ND2 2.7Å; D729-N734 PolarHBondContact OD2-ND2 3.35Å; A731-N734 PolarHBondContact O-N 2.75Å; T732-N734 PolarHBondContact O-N 2.56Å; N734-A746 WeakPolarHBondContact CB-O 3.39Å; N734-A746 PolarHBondContact O-N 2.81Å; N734-S751 WeakPolarHBondContact OD1-CB 3.38Å; N734-S751 PolarHBondContact OD1-OG 3.45Å
735C94.4Very high92.4Very high0 Ų022.4 Ų22.40%011%0.112CC..EExtended strand (participates in β ladder)trans-113.6135170.1-62.40000109.2D671 L672 T732 I743D671-C735 CarbonylContact C-O 3.46Å; D671-C735 VanDerWaalsContact CA-O 3.31Å; D671-C735 WeakPolarHBondContact CA-O 3.38Å; L672-C735 HydrophobicContact CB-CB 3.89Å; L672-C735 HydrophobicContact CD2-CB 3.95Å; L672-C735 PolarHBondContact N-O 3.14Å; T732-C735 PolarHBondContact O-N 3.29Å; C735-I743 HydrophobicContact CB-CG2 4.06Å
736L93.7Very high92.5Very high33 Ų3322 Ų2217%0.17311%0.111CC..EExtended strand (participates in β ladder)trans-106.2148.7177.4-61.8-174.1000112M667 G670 D671 I743 K744 A746 F748M667-L736 HydrophobicContact CB-CB 3.76Å; M667-L736 HydrophobicContact CB-CD1 4.08Å; M667-L736 HydrophobicContact CE-CB 4.17Å; M667-L736 WeakPolarHBondContact CE-O 3.33Å; M667-L736 HydrophobicContact CG-CB 3.75Å; M667-L736 HydrophobicContact CG-CD1 3.95Å; G670-L736 CarbonylContact O-C 3.56Å; G670-L736 WeakPolarHBondContact O-CA 3.46Å; D671-L736 HydrophobicContact CB-CD2 3.96Å; L736-I743 WeakPolarHBondContact O-CA 3.31Å; L736-K744 PolarHBondContact N-O 2.87Å; L736-K744 PolarHBondContact O-N 3.34Å; L736-A746 HydrophobicContact CD1-CB 4.38Å; L736-A746 HydrophobicContact CG-CB 4.34Å; L736-F748 HydrophobicContact CD1-CD2 4.19Å; L736-F748 HydrophobicContact CD1-CE2 3.61Å
737V95.9Very high91.7Very high0 Ų021.5 Ų21.50%011%0.108CC..EExtended strand (participates in β ladder)trans-112.5125-177.2-1680000110.4M667 N669 G670 L672 F675 I743M667-V737 CarbonylContact C-O 3.58Å; N669-V737 WeakPolarHBondContact CA-O 3.45Å; N669-V737 HydrophobicContact CB-CB 3.79Å; N669-V737 HydrophobicContact CB-CG1 3.81Å; N669-V737 WeakPolarHBondContact CB-O 3.33Å; N669-V737 PolarHBondContact N-O 3.18Å; G670-V737 PolarHBondContact O-N 2.65Å; L672-V737 HydrophobicContact CB-CG2 3.92Å; L672-V737 HydrophobicContact CD1-CG2 3.69Å; L672-V737 HydrophobicContact CG-CG2 4.43Å; F675-V737 HydrophobicContact CB-CG2 3.95Å; F675-V737 HydrophobicContact CD1-CG1 4.17Å; F675-V737 HydrophobicContact CD1-CG2 4.13Å; F675-V737 HydrophobicContact CD2-CB 4.46Å; F675-V737 HydrophobicContact CD2-CG1 4.2Å; F675-V737 HydrophobicContact CE1-CG1 4.15Å; F675-V737 HydrophobicContact CE2-CG1 4.16Å; F675-V737 HydrophobicContact CG-CB 4.32Å; F675-V737 HydrophobicContact CG-CG1 4.19Å; F675-V737 HydrophobicContact CG-CG2 3.99Å; F675-V737 HydrophobicContact CZ-CG1 4.13Å; V737-I743 HydrophobicContact CB-CD1 4.45Å; V737-I743 HydrophobicContact CG1-CD1 4.3Å; V737-I743 HydrophobicContact CG2-CD1 3.91Å
738G91.6Very high90Very high5 Ų522.8 Ų22.85%0.05211%0.113CC..  trans-105.4-159.5176.100000111.6N669 T742N669-G738 PolarHBondContact ND2-O 2.98Å; G738-T742 PolarHBondContact N-O 3.39Å
739E90.1Very high88.6Confident68 Ų6820.6 Ų20.632%0.31811%0.109SC..G310 helixtrans-55.2149170.2-66.9176.9-159.500111.7R608 E668 F741 T742R608-E739 IonicContact CZ-OE1 2.7Å; R608-E739 VanDerWaalsContact CZ-OE1 3.24Å; R608-E739 IonicContact CZ-OE2 2.73Å; R608-E739 IonicContact NH1-OE1 3.61Å; R608-E739 PolarHBondContact NH1-OE1 3.25Å; R608-E739 IonicContact NH1-OE2 3.55Å; R608-E739 PolarHBondContact NH1-OE2 3.43Å; R608-E739 VanDerWaalsContact NH2-CD 3.32Å; R608-E739 IonicContact NH2-OE1 2.7Å; R608-E739 PolarHBondContact NH2-OE1 3.04Å; R608-E739 VanDerWaalsContact NH2-OE1 3.14Å; R608-E739 IonicContact NH2-OE2 2.73Å; R608-E739 PolarHBondContact NH2-OE2 3.33Å; E668-E739 WeakPolarHBondContact OE1-CG 3.25Å; E739-F741 VanDerWaalsContact C-N 3.27Å; E739-F741 PolarHBondContact O-N 2.95Å; E739-T742 VanDerWaalsContact O-CB 3.27Å; E739-T742 WeakPolarHBondContact O-CB 3.47Å; E739-T742 PolarHBondContact O-N 2.87Å; E739-T742 PolarHBondContact O-OG1 3.16Å
740N91.1Very high86.7Confident134 Ų13422.4 Ų22.472%0.71712%0.118SC*.G310 helixtrans5436.1170-50.5-55000114.6T742N740-T742 PolarHBondContact O-N 3.06Å
741F93.3Very high84.9Confident54 Ų5423 Ų2324%0.23712%0.122CC..G310 helixtrans59.125.6-176.1-53.3-93.7000114.1F675 I701 M705 V709 Q712 E739 I743F675-F741 AromaticContact CE1-CD1 3.67Å; F675-F741 HydrophobicContact CE1-CD1 3.67Å; F675-F741 AromaticContact CE1-CE1 3.64Å; F675-F741 HydrophobicContact CE1-CE1 3.64Å; F675-F741 AromaticContact CZ-CD1 3.82Å; F675-F741 HydrophobicContact CZ-CD1 3.82Å; F675-F741 AromaticContact CZ-CE1 3.6Å; F675-F741 HydrophobicContact CZ-CE1 3.6Å; I701-F741 HydrophobicContact CD1-CD1 4.01Å; I701-F741 HydrophobicContact CD1-CE1 3.74Å; I701-F741 HydrophobicContact CG1-CE1 4.13Å; M705-F741 HydrophobicContact CE-CD2 3.73Å; M705-F741 HydrophobicContact CE-CE2 4.12Å; M705-F741 HydrophobicContact CE-CG 4.32Å; M705-F741 HydrophobicContact CG-CB 4.21Å; M705-F741 HydrophobicContact CG-CD1 3.8Å; M705-F741 HydrophobicContact CG-CD2 3.94Å; M705-F741 HydrophobicContact CG-CE1 4.11Å; M705-F741 HydrophobicContact CG-CE2 4.25Å; M705-F741 HydrophobicContact CG-CG 3.72Å; M705-F741 HydrophobicContact CG-CZ 4.33Å; M705-F741 HydrophobicContact SD-CB 3.63Å; M705-F741 HydrophobicContact SD-CD1 4.31Å; M705-F741 HydrophobicContact SD-CD2 3.66Å; M705-F741 HydrophobicContact SD-CE2 4.41Å; M705-F741 HydrophobicContact SD-CG 3.62Å; V709-F741 HydrophobicContact CG2-CB 4.44Å; Q712-F741 PolarHBondContact NE2-O 2.92Å; E739-F741 VanDerWaalsContact C-N 3.27Å; E739-F741 PolarHBondContact O-N 2.95Å; F741-I743 PolarHBondContact O-N 2.97Å
742T95.8Very high83.1Confident55 Ų5524.6 Ų24.634%0.33713%0.128SC..  trans-67.3123.6174.3-540000110M667 G738 E739 N740M667-T742 WeakPolarHBondContact CE-O 3.44Å; G738-T742 PolarHBondContact N-O 3.39Å; E739-T742 VanDerWaalsContact O-CB 3.27Å; E739-T742 WeakPolarHBondContact O-CB 3.47Å; E739-T742 PolarHBondContact O-N 2.87Å; E739-T742 PolarHBondContact O-OG1 3.16Å; N740-T742 PolarHBondContact O-N 3.06Å
743I97.6Very high81.6Confident1 Ų129 Ų291%0.00515%0.152CC..EExtended strand (participates in β ladder)trans-103.3134-179.1-53.4-57.7000111.2N646 L672 V709 Q712 I713 C735 L736 V737 F741N646-I743 WeakPolarHBondContact CA-O 3.38Å; N646-I743 PolarHBondContact ND2-O 3.47Å; L672-I743 HydrophobicContact CD1-CD1 3.9Å; L672-I743 HydrophobicContact CD2-CD1 4.44Å; V709-I743 HydrophobicContact CB-CG1 4.29Å; V709-I743 HydrophobicContact CG1-CD1 4.14Å; V709-I743 HydrophobicContact CG1-CG1 4.05Å; V709-I743 HydrophobicContact CG2-CD1 4.14Å; V709-I743 HydrophobicContact CG2-CG1 4.17Å; Q712-I743 HydrophobicContact CB-CB 3.99Å; Q712-I743 HydrophobicContact CB-CG1 4.31Å; I713-I743 HydrophobicContact CG1-CG2 3.81Å; C735-I743 HydrophobicContact CB-CG2 4.06Å; L736-I743 WeakPolarHBondContact O-CA 3.31Å; V737-I743 HydrophobicContact CB-CD1 4.45Å; V737-I743 HydrophobicContact CG1-CD1 4.3Å; V737-I743 HydrophobicContact CG2-CD1 3.91Å; F741-I743 PolarHBondContact O-N 2.97Å
744K95.6Very high80.5Confident21 Ų2134.1 Ų34.19%0.09118%0.179CC..EExtended strand (participates in β ladder)trans-125.5124.7166.7-67.5-177.9164.7-60.70111.3P645 N646 I647 I648 M667 L736P645-K744 PolarHBondContact O-NZ 3.1Å; N646-K744 WeakPolarHBondContact O-CA 3.34Å; I647-K744 PolarHBondContact O-NZ 2.88Å; I648-K744 HydrophobicContact CD1-CD 4.26Å; M667-K744 HydrophobicContact CE-CB 3.87Å; M667-K744 HydrophobicContact CE-CD 4Å; M667-K744 HydrophobicContact CE-CG 3.8Å; M667-K744 HydrophobicContact SD-CD 3.8Å; M667-K744 HydrophobicContact SD-CG 4.3Å; L736-K744 PolarHBondContact N-O 2.87Å; L736-K744 PolarHBondContact O-N 3.34Å
745I94.4Very high80Confident1 Ų135.3 Ų35.31%0.00518%0.183CC..EExtended strand (participates in β ladder)trans-74.2139.5173.4-47.1175.9000109.4N646 I647 I648 I713 M717 H727 L730N646-I745 PolarHBondContact O-N 3.26Å; I647-I745 HydrophobicContact CD1-CB 3.96Å; I647-I745 HydrophobicContact CD1-CD1 4.11Å; I647-I745 HydrophobicContact CD1-CG1 4.3Å; I648-I745 WeakPolarHBondContact CG2-O 3.43Å; I648-I745 PolarHBondContact N-O 2.8Å; I713-I745 HydrophobicContact CG2-CD1 3.97Å; I713-I745 HydrophobicContact CG2-CG1 4.45Å; M717-I745 HydrophobicContact CG-CD1 3.63Å; M717-I745 HydrophobicContact SD-CD1 3.73Å; H727-I745 WeakPolarHBondContact NE2-CG2 3.48Å; L730-I745 HydrophobicContact CD1-CD1 4.27Å; L730-I745 HydrophobicContact CD1-CG2 3.99Å
746A85.4Confident79.2Confident2 Ų237.5 Ų37.52%0.01720%0.201CC..  trans-147.6160.9-174.800000113.4I648 N734 L736 F748I648-A746 HydrophobicContact CB-CB 3.93Å; I648-A746 HydrophobicContact CG1-CB 4.49Å; I648-A746 HydrophobicContact CG2-CB 3.66Å; N734-A746 WeakPolarHBondContact CB-O 3.39Å; N734-A746 PolarHBondContact O-N 2.81Å; L736-A746 HydrophobicContact CD1-CB 4.38Å; L736-A746 HydrophobicContact CG-CB 4.34Å; A746-F748 HydrophobicContact CB-CD2 3.61Å; A746-F748 HydrophobicContact CB-CE2 3.58Å
747D69.1Low78.6Confident3 Ų338.6 Ų38.62%0.01622%0.22CC..  trans-133.557.8178.8-173.427.4000110.5T548 Y549 G749T548-D747 WeakPolarHBondContact CA-OD2 3.32Å; T548-D747 WeakPolarHBondContact CB-OD1 3.49Å; T548-D747 WeakPolarHBondContact CB-OD2 3.46Å; T548-D747 PolarHBondContact N-OD2 3.48Å; T548-D747 PolarHBondContact OG1-OD1 3.38Å; T548-D747 PolarHBondContact OG1-OD2 3.27Å; Y549-D747 HydrophobicContact CD1-CB 4.35Å; Y549-D747 HydrophobicContact CD2-CB 4.25Å; Y549-D747 HydrophobicContact CE1-CB 3.66Å; Y549-D747 HydrophobicContact CE2-CB 3.56Å; Y549-D747 VanDerWaalsContact OH-CB 3.29Å; Y549-D747 WeakPolarHBondContact OH-CB 3.41Å; Y549-D747 PolarHBondContact OH-N 2.96Å; D747-G749 PolarHBondContact O-N 2.96Å
748F53.8Low78.1Confident26 Ų2639.4 Ų39.411%0.11423%0.225CC..  trans-68.4-12.1-177.3-77.6-79.2000113.7V587 K618 I648 T664 L736 A746 M750V587-F748 HydrophobicContact CG2-CD1 3.98Å; K618-F748 HydrophobicContact CD-CD1 4.29Å; K618-F748 WeakPolarHBondContact CE-O 3.43Å; K618-F748 PolarHBondContact NZ-O 2.87Å; I648-F748 HydrophobicContact CD1-CZ 4.47Å; I648-F748 HydrophobicContact CG1-CE2 4.04Å; I648-F748 HydrophobicContact CG1-CZ 3.96Å; T664-F748 HydrophobicContact CG2-CZ 4.43Å; L736-F748 HydrophobicContact CD1-CD2 4.19Å; L736-F748 HydrophobicContact CD1-CE2 3.61Å; A746-F748 HydrophobicContact CB-CD2 3.61Å; A746-F748 HydrophobicContact CB-CE2 3.58Å; F748-M750 HydrophobicContact CB-CE 4.02Å; F748-M750 HydrophobicContact CB-CG 4.25Å; F748-M750 HydrophobicContact CG-CE 4.36Å; F748-M750 PolarHBondContact O-N 3.47Å
749G57.7Low77.7Confident13 Ų1339.7 Ų39.713%0.13422%0.224CC..SBendtrans69.3-7.3-177.300000115.1D747D747-G749 PolarHBondContact O-N 2.96Å
750M51.5Low77.3Confident40 Ų4039 Ų3920%0.19722%0.219CC..  trans-73.3-32.6179.7-60.2-168.2-62.700113.1G580 V587 F748 R752 N753G580-M750 VanDerWaalsContact CA-SD 3.56Å; V587-M750 HydrophobicContact CB-CE 3.81Å; V587-M750 HydrophobicContact CB-SD 3.53Å; V587-M750 VanDerWaalsContact CB-SD 3.53Å; V587-M750 HydrophobicContact CG1-CE 4.34Å; V587-M750 HydrophobicContact CG2-CE 3.66Å; V587-M750 HydrophobicContact CG2-CG 4.29Å; V587-M750 HydrophobicContact CG2-SD 3.31Å; V587-M750 WeakPolarHBondContact CG2-SD 3.47Å; F748-M750 HydrophobicContact CB-CE 4.02Å; F748-M750 HydrophobicContact CB-CG 4.25Å; F748-M750 HydrophobicContact CG-CE 4.36Å; F748-M750 PolarHBondContact O-N 3.47Å; M750-R752 PolarHBondContact O-N 3.38Å; M750-R752 VanDerWaalsContact O-N 3.12Å; M750-N753 PolarHBondContact O-N 2.92Å
751S56Low76.5Confident13 Ų1340.5 Ų40.59%0.09122%0.215CC..Hα-helixtrans-53.3-33.4178.848.40000112.2N734 N753 L754 Y755N734-S751 WeakPolarHBondContact OD1-CB 3.38Å; N734-S751 PolarHBondContact OD1-OG 3.45Å; S751-N753 PolarHBondContact O-N 2.84Å; S751-N753 VanDerWaalsContact O-N 3.12Å; S751-L754 PolarHBondContact O-N 2.96Å; S751-Y755 WeakPolarHBondContact O-CA 3.31Å; S751-Y755 WeakPolarHBondContact O-CB 3.48Å; S751-Y755 WeakPolarHBondContact O-CD2 3.15Å; S751-Y755 PolarHBondContact O-N 2.88Å
752R58.8Low74.8Confident33 Ų3339.3 Ų39.313%0.12521%0.212CC..Hα-helixtrans-60.8-19.8178.1-56.7-174.8-175-178.57.8115.1N547 T548 M750 Y759N547-R752 PolarHBondContact O-NH2 2.84Å; T548-R752 PolarHBondContact OG1-NH2 3.42Å; M750-R752 PolarHBondContact O-N 3.38Å; M750-R752 VanDerWaalsContact O-N 3.12Å; R752-Y759 HydrophobicContact CB-CE2 4.28Å; R752-Y759 HydrophobicContact CG-CE1 4.09Å; R752-Y759 HydrophobicContact CG-CE2 4.01Å
753N63.2Low72.3Confident92 Ų9245.7 Ų45.749%0.49224%0.238SC..Hα-helixtrans-89.5-42.7175.4-79.5-16.2000112.3E581 M750 S751E581-N753 PolarHBondContact O-ND2 3.04Å; M750-N753 PolarHBondContact O-N 2.92Å; S751-N753 PolarHBondContact O-N 2.84Å; S751-N753 VanDerWaalsContact O-N 3.12Å
754L69.7Low69.8Low115 Ų11550 Ų5060%0.60228%0.283SS*.Hα-helixtrans-75.2-43.9179.9-178.359.2000111.7S751 A756S751-L754 PolarHBondContact O-N 2.96Å; L754-A756 VanDerWaalsContact C-N 3.32Å; L754-A756 PolarHBondContact O-N 3.03Å
755Y80.7Confident67.6Low33 Ų3353.7 Ų53.713%0.12930%0.296CS..THydrogen-bonded Turntrans-95.236.7-178.5-62.5-80.8000112.2D671 N673 Q674 R733 S751 G757 D758 Y759D671-Y755 PolarHBondContact OD1-OH 2.95Å; N673-Y755 HydrophobicContact CB-CE1 4.27Å; N673-Y755 VanDerWaalsContact OD1-CE1 3.23Å; N673-Y755 WeakPolarHBondContact OD1-CE1 3.31Å; N673-Y755 PolarHBondContact OD1-OH 2.71Å; Q674-Y755 WeakPolarHBondContact CG-OH 3.47Å; R733-Y755 HydrophobicContact CB-CD1 4.3Å; R733-Y755 HydrophobicContact CB-CD2 3.57Å; R733-Y755 HydrophobicContact CB-CE1 4.34Å; R733-Y755 HydrophobicContact CB-CE2 3.61Å; R733-Y755 HydrophobicContact CB-CG 3.94Å; R733-Y755 HydrophobicContact CG-CD2 4.39Å; R733-Y755 HydrophobicContact CG-CG 4.48Å; S751-Y755 WeakPolarHBondContact O-CA 3.31Å; S751-Y755 WeakPolarHBondContact O-CB 3.48Å; S751-Y755 WeakPolarHBondContact O-CD2 3.15Å; S751-Y755 PolarHBondContact O-N 2.88Å; Y755-G757 PolarHBondContact O-N 2.88Å; Y755-D758 WeakPolarHBondContact O-CB 3.39Å; Y755-D758 PolarHBondContact O-N 3.2Å; Y755-Y759 VanDerWaalsContact O-CD2 3.31Å; Y755-Y759 WeakPolarHBondContact O-CD2 3.35Å
756A79.2Confident66Low46 Ų4654 Ų5438%0.3830%0.299SS..G310 helixtrans-56.4-27.2-173.900000114L754 D758 Y759L754-A756 VanDerWaalsContact C-N 3.32Å; L754-A756 PolarHBondContact O-N 3.03Å; A756-D758 VanDerWaalsContact C-N 3.32Å; A756-D758 PolarHBondContact O-N 3.14Å; A756-Y759 PolarHBondContact O-N 2.76Å
757G80.8Confident65.5Low55 Ų5556 Ų5657%0.56731%0.31SS*.G310 helixtrans-76.9-5.8175.100000115.8Y755 Q806Y755-G757 PolarHBondContact O-N 2.88Å; G757-Q806 PolarHBondContact O-NE2 2.9Å
758D85.1Confident66.2Low17 Ų1756.3 Ų56.39%0.09131%0.312CS..G310 helixtrans-85.9-12.1170.4-73.1-15.9000112.6R733 Y755 A756 P769 W772 Q806R733-D758 IonicContact CZ-OD2 2.63Å; R733-D758 IonicContact NE-OD2 2.7Å; R733-D758 VanDerWaalsContact NH1-CG 3.33Å; R733-D758 IonicContact NH1-OD2 2.73Å; R733-D758 PolarHBondContact NH1-OD2 3.13Å; Y755-D758 WeakPolarHBondContact O-CB 3.39Å; Y755-D758 PolarHBondContact O-N 3.2Å; A756-D758 VanDerWaalsContact C-N 3.32Å; A756-D758 PolarHBondContact O-N 3.14Å; D758-P769 WeakPolarHBondContact O-CA 3.44Å; D758-W772 HydrophobicContact CB-CH2 4Å; D758-W772 HydrophobicContact CB-CZ3 3.66Å; D758-W772 WeakPolarHBondContact OD1-CH2 3.48Å; D758-W772 WeakPolarHBondContact OD2-CH2 3.31Å; D758-Q806 PolarHBondContact OD1-NE2 2.97Å
759Y83.8Confident67.9Low11 Ų1155.3 Ų55.34%0.04331%0.308CS..SBendtrans-119.1106.8-169.9-65.3-87.5000113D729 R733 R752 Y755 A756 V767 L768 P769D729-Y759 PolarHBondContact OD1-OH 3.16Å; D729-Y759 WeakPolarHBondContact OD2-CE1 3.37Å; D729-Y759 PolarHBondContact OD2-OH 3.32Å; R733-Y759 PolarHBondContact NE-OH 2.94Å; R752-Y759 HydrophobicContact CB-CE2 4.28Å; R752-Y759 HydrophobicContact CG-CE1 4.09Å; R752-Y759 HydrophobicContact CG-CE2 4.01Å; Y755-Y759 VanDerWaalsContact O-CD2 3.31Å; Y755-Y759 WeakPolarHBondContact O-CD2 3.35Å; A756-Y759 PolarHBondContact O-N 2.76Å; Y759-V767 HydrophobicContact CD1-CG1 4.22Å; Y759-V767 HydrophobicContact CG-CG1 4.17Å; Y759-L768 CarbonylContact C-O 3.38Å; Y759-L768 WeakPolarHBondContact CA-O 3.4Å; Y759-P769 HydrophobicContact CD1-CB 3.95Å; Y759-P769 HydrophobicContact CE1-CB 3.79Å; Y759-P769 HydrophobicContact CE1-CG 4.25Å
760Y81.8Confident69.5Low53 Ų5354.9 Ų54.921%0.20830%0.303CS..EExtended strand (participates in β ladder)trans-67.6143.6174.6-172.6-123.3000111.6V762 L768 I770 D813 I817Y760-V762 HydrophobicContact CD1-CG2 3.73Å; Y760-V762 HydrophobicContact CE1-CG2 3.44Å; Y760-V762 VanDerWaalsContact CE1-CG2 3.44Å; Y760-L768 PolarHBondContact N-O 3.24Å; Y760-L768 PolarHBondContact O-N 2.86Å; Y760-I770 HydrophobicContact CD1-CD1 4.36Å; Y760-I770 HydrophobicContact CG-CD1 4.06Å; Y760-D813 HydrophobicContact CD2-CB 3.45Å; Y760-D813 VanDerWaalsContact CD2-CB 3.45Å; Y760-D813 WeakPolarHBondContact CD2-OD2 3.39Å; Y760-D813 HydrophobicContact CE2-CB 3.76Å; Y760-D813 HydrophobicContact CG-CB 4.13Å; Y760-I817 HydrophobicContact CD1-CD1 3.74Å; Y760-I817 HydrophobicContact CE1-CD1 3.37Å
761R72.9Confident71.7Confident166 Ų16653.5 Ų53.563%0.62630%0.296SS*.EExtended strand (participates in β ladder)trans-123.794.5-177-61.7-169179.2-175.1-0.1111.2V767R761-V767 HydrophobicContact CG-CG1 4.31Å; R761-V767 HydrophobicContact CG-CG2 4.17Å
762V58.8Low73.6Confident30 Ų3053.1 Ų53.118%0.18229%0.292CS..  trans-72131.3172.41790000109.7Y760 G764 R765Y760-V762 HydrophobicContact CD1-CG2 3.73Å; Y760-V762 HydrophobicContact CE1-CG2 3.44Å; Y760-V762 VanDerWaalsContact CE1-CG2 3.44Å; V762-G764 PolarHBondContact O-N 3.08Å; V762-R765 HydrophobicContact CB-CB 4.05Å; V762-R765 HydrophobicContact CG1-CB 4.01Å; V762-R765 HydrophobicContact CG1-CG 4.08Å; V762-R765 PolarHBondContact O-N 3.23Å
763Q43.3Very low75.3Confident188 Ų18852 Ų5288%0.87929%0.288SS*.THydrogen-bonded Turntrans-55.9129.9-178.8-65.5-171.75.700111.5R765Q763-R765 PolarHBondContact O-N 3.06Å; Q763-R765 VanDerWaalsContact O-N 3.15Å
764G43.3Very low76.9Confident92 Ų9247.6 Ų47.695%0.94827%0.265SS*.THydrogen-bonded Turntrans691.5-17900000115.9V762V762-G764 PolarHBondContact O-N 3.08Å
765R50.1Low78.1Confident99 Ų9943 Ų4337%0.37424%0.239SC..SBendtrans-122.4-172.7-177.7-57.2-171.6-178.5133.1-7.3110.9D536 I537 V762 Q763D536-R765 IonicContact OD1-CZ 3.13Å; D536-R765 IonicContact OD1-NH2 3.6Å; D536-R765 PolarHBondContact OD1-NH2 3.18Å; I537-R765 WeakPolarHBondContact O-CD 3.37Å; I537-R765 PolarHBondContact O-NE 3.33Å; V762-R765 HydrophobicContact CB-CB 4.05Å; V762-R765 HydrophobicContact CG1-CB 4.01Å; V762-R765 HydrophobicContact CG1-CG 4.08Å; V762-R765 PolarHBondContact O-N 3.23Å; Q763-R765 PolarHBondContact O-N 3.06Å; Q763-R765 VanDerWaalsContact O-N 3.15Å
766A61.2Low78.5Confident7 Ų741.5 Ų41.56%0.05823%0.234CC..  trans-82.1166.1-172.900000113.7L540 V543 T544L540-A766 HydrophobicContact CB-CB 3.87Å; L540-A766 HydrophobicContact CD1-CB 4.14Å; V543-A766 HydrophobicContact CB-CB 3.93Å; V543-A766 HydrophobicContact CG2-CB 3.45Å; V543-A766 VanDerWaalsContact CG2-CB 3.45Å; T544-A766 HydrophobicContact CG2-CB 4.19Å
767V74Confident78.9Confident43 Ų4339.4 Ų39.426%0.26122%0.216SC..EExtended strand (participates in β ladder)trans-93.9129.4-176.8179.90000109.6V543 Y759 R761V543-V767 WeakPolarHBondContact CB-O 3.15Å; V543-V767 VanDerWaalsContact CG1-O 3.27Å; V543-V767 WeakPolarHBondContact CG1-O 3.19Å; Y759-V767 HydrophobicContact CD1-CG1 4.22Å; Y759-V767 HydrophobicContact CG-CG1 4.17Å; R761-V767 HydrophobicContact CG-CG1 4.31Å; R761-V767 HydrophobicContact CG-CG2 4.17Å
768L83.6Confident79.2Confident11 Ų1137.9 Ų37.96%0.05820%0.195CC..EExtended strand (participates in β ladder)trans-134.9132.6-165.2-73.6179.3000114.9L540 V543 Y759 Y760 I770 M773 F783L540-L768 HydrophobicContact CD1-CD1 3.76Å; L540-L768 HydrophobicContact CD1-CD2 4.1Å; L540-L768 HydrophobicContact CD1-CG 4.15Å; L540-L768 HydrophobicContact CD2-CD2 4.31Å; V543-L768 HydrophobicContact CG2-CD2 4.01Å; Y759-L768 CarbonylContact C-O 3.38Å; Y759-L768 WeakPolarHBondContact CA-O 3.4Å; Y760-L768 PolarHBondContact N-O 3.24Å; Y760-L768 PolarHBondContact O-N 2.86Å; L768-I770 HydrophobicContact CB-CG2 3.8Å; L768-I770 HydrophobicContact CD1-CG2 4.45Å; L768-I770 PolarHBondContact O-N 2.76Å; L768-M773 HydrophobicContact CB-SD 3.88Å; L768-M773 HydrophobicContact CD1-CE 4.12Å; L768-M773 HydrophobicContact CD1-SD 4.38Å; L768-M773 HydrophobicContact CD2-CE 3.98Å; L768-M773 HydrophobicContact CD2-SD 3.94Å; L768-M773 HydrophobicContact CG-CE 4.49Å; L768-M773 HydrophobicContact CG-SD 4.3Å; L768-F783 HydrophobicContact CD2-CZ 4.48Å
769P90.3Very high79Confident4 Ų440.4 Ų40.43%0.02621%0.208CC..  trans-79.958.5175.535.7-37000111.8D729 D758 Y759 R771 W772 M773D729-P769 HydrophobicContact CB-CG 4.17Å; D729-P769 WeakPolarHBondContact OD1-CB 3.31Å; D729-P769 WeakPolarHBondContact OD1-CG 3.34Å; D758-P769 WeakPolarHBondContact O-CA 3.44Å; Y759-P769 HydrophobicContact CD1-CB 3.95Å; Y759-P769 HydrophobicContact CE1-CB 3.79Å; Y759-P769 HydrophobicContact CE1-CG 4.25Å; P769-R771 PolarHBondContact O-N 2.84Å; P769-W772 HydrophobicContact CB-CE3 4.37Å; P769-W772 PolarHBondContact O-N 3.45Å; P769-M773 HydrophobicContact CG-CG 4.24Å; P769-M773 HydrophobicContact CG-SD 4.3Å; P769-M773 WeakPolarHBondContact O-CG 3.46Å; P769-M773 PolarHBondContact O-N 3.04Å
770I91.9Very high78.7Confident5 Ų545.1 Ų45.13%0.02623%0.232CC..THydrogen-bonded Turntrans-54.4-29-166.259.4166.4000114.6Y760 L768 W772 M773 I778 D813 V816 I817Y760-I770 HydrophobicContact CD1-CD1 4.36Å; Y760-I770 HydrophobicContact CG-CD1 4.06Å; L768-I770 HydrophobicContact CB-CG2 3.8Å; L768-I770 HydrophobicContact CD1-CG2 4.45Å; L768-I770 PolarHBondContact O-N 2.76Å; I770-W772 PolarHBondContact O-N 3.15Å; I770-M773 HydrophobicContact CG2-SD 4.18Å; I770-M773 PolarHBondContact O-N 3.32Å; I770-I778 HydrophobicContact CB-CD1 4.47Å; I770-D813 HydrophobicContact CD1-CB 3.68Å; I770-D813 WeakPolarHBondContact CD1-O 3.4Å; I770-V816 HydrophobicContact CB-CG1 4.43Å; I770-V816 HydrophobicContact CD1-CB 4.15Å; I770-V816 HydrophobicContact CD1-CG1 4.05Å; I770-V816 HydrophobicContact CG1-CG1 4.18Å; I770-I817 HydrophobicContact CD1-CD1 4.17Å; I770-I817 HydrophobicContact CD1-CG1 4.01Å
771R96.6Very high78.6Confident11 Ų1144.2 Ų44.24%0.04224%0.239CC..THydrogen-bonded Turntrans-70.4-15.9179.4-69.3162.9-176.7-81.3-5.2113.9P769 P807 F808 L811 D813 V816P769-R771 PolarHBondContact O-N 2.84Å; R771-P807 HydrophobicContact CB-CB 4.35Å; R771-P807 PolarHBondContact NH1-O 3.08Å; R771-F808 PolarHBondContact NH1-O 3.02Å; R771-L811 PolarHBondContact NH1-O 3.4Å; R771-L811 PolarHBondContact NH2-O 2.91Å; R771-D813 IonicContact CZ-OD1 3.84Å; R771-D813 VanDerWaalsContact CZ-OD1 3.3Å; R771-D813 IonicContact NE-OD1 2.64Å; R771-D813 PolarHBondContact NE-OD1 2.95Å; R771-D813 IonicContact NH2-OD1 2.74Å; R771-D813 PolarHBondContact NH2-OD1 3.33Å; R771-V816 HydrophobicContact CG-CG1 4.24Å; R771-V816 HydrophobicContact CG-CG2 4.19Å
772W96.9Very high79Confident4 Ų441.4 Ų41.42%0.01523%0.231CC..THydrogen-bonded Turntrans-105.6-12.3173.3-71.1-103.4000113.2A731 D758 P769 I770 A791 V794 E798 Q806 P807A731-W772 HydrophobicContact CB-CD2 4.26Å; A731-W772 HydrophobicContact CB-CG 4.24Å; A731-W772 HydrophobicContact CB-CZ2 4.39Å; A731-W772 VanDerWaalsContact CB-NE1 3.34Å; D758-W772 HydrophobicContact CB-CH2 4Å; D758-W772 HydrophobicContact CB-CZ3 3.66Å; D758-W772 WeakPolarHBondContact OD1-CH2 3.48Å; D758-W772 WeakPolarHBondContact OD2-CH2 3.31Å; P769-W772 HydrophobicContact CB-CE3 4.37Å; P769-W772 PolarHBondContact O-N 3.45Å; I770-W772 PolarHBondContact O-N 3.15Å; W772-A791 HydrophobicContact CB-CB 4.42Å; W772-A791 WeakPolarHBondContact O-CA 3.39Å; W772-A791 WeakPolarHBondContact O-CB 3.43Å; W772-V794 HydrophobicContact CD2-CG1 4.29Å; W772-V794 HydrophobicContact CG-CB 4.37Å; W772-V794 HydrophobicContact CG-CG1 3.95Å; W772-E798 HydrophobicContact CZ2-CG 4.36Å; W772-E798 PolarHBondContact NE1-OE2 3.02Å; W772-Q806 HydrophobicContact CH2-CG 4.45Å; W772-P807 HydrophobicContact CH2-CG 4.02Å; W772-P807 HydrophobicContact CZ2-CG 3.64Å
773M94.8Very high80.3Confident10 Ų1041.6 Ų41.65%0.04923%0.229CC..SBendtrans-80.1141.4-173.3-71.9170.362.800112.1L768 P769 I770 C777 I778 F783 W790L768-M773 HydrophobicContact CB-SD 3.88Å; L768-M773 HydrophobicContact CD1-CE 4.12Å; L768-M773 HydrophobicContact CD1-SD 4.38Å; L768-M773 HydrophobicContact CD2-CE 3.98Å; L768-M773 HydrophobicContact CD2-SD 3.94Å; L768-M773 HydrophobicContact CG-CE 4.49Å; L768-M773 HydrophobicContact CG-SD 4.3Å; P769-M773 HydrophobicContact CG-CG 4.24Å; P769-M773 HydrophobicContact CG-SD 4.3Å; P769-M773 WeakPolarHBondContact O-CG 3.46Å; P769-M773 PolarHBondContact O-N 3.04Å; I770-M773 HydrophobicContact CG2-SD 4.18Å; I770-M773 PolarHBondContact O-N 3.32Å; M773-C777 HydrophobicContact CB-CB 4.14Å; M773-C777 HydrophobicContact CE-CB 3.65Å; M773-C777 WeakPolarHBondContact CE-O 3.41Å; M773-C777 HydrophobicContact CG-CB 4.47Å; M773-I778 HydrophobicContact CB-CD1 4.03Å; M773-I778 HydrophobicContact CB-CG1 3.69Å; M773-I778 HydrophobicContact CE-CG1 3.96Å; M773-I778 HydrophobicContact SD-CG1 4.48Å; M773-F783 HydrophobicContact CE-CE1 4.21Å; M773-F783 HydrophobicContact CE-CZ 3.87Å; M773-W790 PolarHBondContact O-NE1 2.71Å; M773-W790 VanDerWaalsContact O-NE1 3.17Å
774A96.3Very high82.5Confident0 Ų034.6 Ų34.60%020%0.199CC..  trans-68.1155.7168.500000111.5E776 C777 I778 W790A774-E776 VanDerWaalsContact CB-CD 3.45Å; A774-E776 VanDerWaalsContact CB-OE1 3.26Å; A774-E776 WeakPolarHBondContact CB-OE1 3.33Å; A774-E776 VanDerWaalsContact CB-OE2 3.3Å; A774-E776 WeakPolarHBondContact CB-OE2 3.24Å; A774-E776 PolarHBondContact O-N 2.86Å; A774-C777 WeakPolarHBondContact O-CA 3.5Å; A774-C777 WeakPolarHBondContact O-CB 3.39Å; A774-C777 PolarHBondContact O-N 2.94Å; A774-I778 PolarHBondContact O-N 3.13Å; A774-W790 HydrophobicContact CB-CB 3.79Å; A774-W790 HydrophobicContact CB-CD2 3.66Å; A774-W790 HydrophobicContact CB-CE3 3.91Å; A774-W790 HydrophobicContact CB-CG 3.62Å
775W94.3Very high85Confident18 Ų1832.4 Ų32.47%0.06817%0.167CC..Hα-helixtrans-57.2-36.8-177.374.7-95.2000112.2C777 I778 L779 M780 A820 F823 F824 R853W775-C777 VanDerWaalsContact C-N 3.29Å; W775-C777 PolarHBondContact O-N 3.21Å; W775-I778 PolarHBondContact O-N 2.88Å; W775-L779 HydrophobicContact CE3-CD1 4.12Å; W775-L779 PolarHBondContact O-N 3.16Å; W775-M780 HydrophobicContact CE3-CE 4.49Å; W775-M780 HydrophobicContact CH2-CE 3.65Å; W775-M780 HydrophobicContact CZ3-CE 3.56Å; W775-M780 HydrophobicContact CZ3-SD 4.43Å; W775-A820 HydrophobicContact CB-CB 4.17Å; W775-F823 HydrophobicContact CB-CB 3.77Å; W775-F823 HydrophobicContact CG-CB 3.95Å; W775-F824 HydrophobicContact CE3-CB 3.85Å; W775-F824 HydrophobicContact CE3-CD2 4.16Å; W775-F824 HydrophobicContact CE3-CG 4.4Å; W775-F824 AromaticContact CH2-CD2 3.73Å; W775-F824 HydrophobicContact CH2-CD2 3.73Å; W775-F824 HydrophobicContact CH2-CE2 4.41Å; W775-F824 HydrophobicContact CZ3-CB 4Å; W775-F824 AromaticContact CZ3-CD2 3.41Å; W775-F824 HydrophobicContact CZ3-CD2 3.41Å; W775-F824 VanDerWaalsContact CZ3-CD2 3.41Å; W775-F824 HydrophobicContact CZ3-CE2 4.26Å; W775-F824 HydrophobicContact CZ3-CG 4.05Å; W775-R853 HydrophobicContact CZ2-CG 4.35Å; W775-R853 PolarHBondContact NE1-O 3.34Å
776E89.1Confident87.2Confident1 Ų128.6 Ų28.61%0.00516%0.158CC..Hα-helixtrans-70.5-22.5177.573.7-79.9-177.800113.6A774 M780 G781 K782 R858A774-E776 VanDerWaalsContact CB-CD 3.45Å; A774-E776 VanDerWaalsContact CB-OE1 3.26Å; A774-E776 WeakPolarHBondContact CB-OE1 3.33Å; A774-E776 VanDerWaalsContact CB-OE2 3.3Å; A774-E776 WeakPolarHBondContact CB-OE2 3.24Å; A774-E776 PolarHBondContact O-N 2.86Å; E776-M780 HydrophobicContact CB-CE 3.57Å; E776-M780 CarbonylContact O-C 3.57Å; E776-M780 WeakPolarHBondContact O-CA 3.49Å; E776-M780 WeakPolarHBondContact O-CB 3.41Å; E776-M780 PolarHBondContact O-N 2.79Å; E776-M780 VanDerWaalsContact O-N 3.1Å; E776-G781 PolarHBondContact O-N 2.84Å; E776-K782 HydrophobicContact CB-CB 4.28Å; E776-K782 HydrophobicContact CG-CB 4.13Å; E776-K782 HydrophobicContact CG-CD 4.31Å; E776-K782 PolarHBondContact O-N 2.95Å; E776-R858 IonicContact OE1-CZ 3.14Å; E776-R858 IonicContact OE1-NH1 3.29Å; E776-R858 PolarHBondContact OE1-NH1 3.04Å; E776-R858 IonicContact OE1-NH2 2.65Å; E776-R858 PolarHBondContact OE1-NH2 2.9Å; E776-R858 IonicContact OE2-CZ 2.7Å; E776-R858 IonicContact OE2-NH1 2.7Å; E776-R858 IonicContact OE2-NH2 3.87Å; E776-R858 PolarHBondContact OE2-NH2 2.73Å
777C88.9Confident88.8Confident2 Ų228.5 Ų28.51%0.01416%0.156CC..Hα-helixtrans-77.7-36.7173.2-65.40000111.6M773 A774 W775 G781 K782 F783 S787M773-C777 HydrophobicContact CB-CB 4.14Å; M773-C777 HydrophobicContact CE-CB 3.65Å; M773-C777 WeakPolarHBondContact CE-O 3.41Å; M773-C777 HydrophobicContact CG-CB 4.47Å; A774-C777 WeakPolarHBondContact O-CA 3.5Å; A774-C777 WeakPolarHBondContact O-CB 3.39Å; A774-C777 PolarHBondContact O-N 2.94Å; W775-C777 VanDerWaalsContact C-N 3.29Å; W775-C777 PolarHBondContact O-N 3.21Å; C777-G781 WeakPolarHBondContact O-CA 3.5Å; C777-G781 PolarHBondContact O-N 3.05Å; C777-K782 PolarHBondContact SG-O 2.87Å; C777-F783 HydrophobicContact CB-CD1 4.27Å; C777-F783 HydrophobicContact CB-CE1 4.04Å; C777-F783 HydrophobicContact CB-CZ 4.3Å; C777-S787 WeakPolarHBondContact SG-CB 3.36Å; C777-S787 PolarHBondContact SG-OG 3.12Å
778I85.2Confident89.9Confident23 Ų2326.6 Ų26.612%0.11815%0.145CC..Hα-helixtrans-74.2-48.4179.7-61.4169000110.4I770 M773 A774 W775 I817 A820I770-I778 HydrophobicContact CB-CD1 4.47Å; M773-I778 HydrophobicContact CB-CD1 4.03Å; M773-I778 HydrophobicContact CB-CG1 3.69Å; M773-I778 HydrophobicContact CE-CG1 3.96Å; M773-I778 HydrophobicContact SD-CG1 4.48Å; A774-I778 PolarHBondContact O-N 3.13Å; W775-I778 PolarHBondContact O-N 2.88Å; I778-I817 HydrophobicContact CG2-CG1 4.16Å; I778-I817 HydrophobicContact CG2-CG2 4.23Å; I778-A820 HydrophobicContact CB-CB 4.13Å; I778-A820 HydrophobicContact CD1-CB 3.75Å; I778-A820 HydrophobicContact CG2-CB 4.12Å
779L81.8Confident90.6Very high70 Ų7026.2 Ų26.237%0.36614%0.143SC..Hα-helixtrans-87.2-26.7-174-57.5-174.2000114.3W775 F824W775-L779 HydrophobicContact CE3-CD1 4.12Å; W775-L779 PolarHBondContact O-N 3.16Å; L779-F824 HydrophobicContact CD1-CB 3.68Å; L779-F824 HydrophobicContact CD1-CD1 4.49Å; L779-F824 HydrophobicContact CD1-CG 4.17Å
780M78.2Confident91Very high111 Ų11126.6 Ų26.655%0.54714%0.144SC..Hα-helixtrans-130.42.1-172.5-53.8-174.7-66.200114.2W775 E776 K782W775-M780 HydrophobicContact CE3-CE 4.49Å; W775-M780 HydrophobicContact CH2-CE 3.65Å; W775-M780 HydrophobicContact CZ3-CE 3.56Å; W775-M780 HydrophobicContact CZ3-SD 4.43Å; E776-M780 HydrophobicContact CB-CE 3.57Å; E776-M780 CarbonylContact O-C 3.57Å; E776-M780 WeakPolarHBondContact O-CA 3.49Å; E776-M780 WeakPolarHBondContact O-CB 3.41Å; E776-M780 PolarHBondContact O-N 2.79Å; E776-M780 VanDerWaalsContact O-N 3.1Å; M780-K782 HydrophobicContact CB-CB 4.41Å; M780-K782 PolarHBondContact O-N 3.48Å; M780-K782 VanDerWaalsContact O-N 3.16Å
781G79.1Confident91.3Very high34 Ų3426.6 Ų26.635%0.35114%0.144SC..  trans63.516-177.900000114.9E776 C777 F783E776-G781 PolarHBondContact O-N 2.84Å; C777-G781 WeakPolarHBondContact O-CA 3.5Å; C777-G781 PolarHBondContact O-N 3.05Å; G781-F783 WeakPolarHBondContact O-CD2 3.29Å; G781-F783 PolarHBondContact O-N 2.93Å; G781-F783 VanDerWaalsContact O-N 3.08Å
782K81.9Confident91.4Very high106 Ų10626.1 Ų26.146%0.46114%0.143SC..  trans-86.972.6-166.8-169.1-166.8171.2-170.80113.1E776 C777 M780 T784E776-K782 HydrophobicContact CB-CB 4.28Å; E776-K782 HydrophobicContact CG-CB 4.13Å; E776-K782 HydrophobicContact CG-CD 4.31Å; E776-K782 PolarHBondContact O-N 2.95Å; C777-K782 PolarHBondContact SG-O 2.87Å; M780-K782 HydrophobicContact CB-CB 4.41Å; M780-K782 PolarHBondContact O-N 3.48Å; M780-K782 VanDerWaalsContact O-N 3.16Å; K782-T784 HydrophobicContact CG-CG2 4.34Å
783F85.6Confident91.5Very high35 Ų3525.9 Ų25.915%0.15414%0.142CC..  trans-70.2127.5175.9-62.7-86.9000112.9L540 V726 R728 L768 M773 C777 G781L540-F783 HydrophobicContact CD2-CE2 3.91Å; L540-F783 HydrophobicContact CD2-CZ 4.45Å; V726-F783 HydrophobicContact CG1-CB 4.39Å; R728-F783 HydrophobicContact CB-CD1 3.63Å; R728-F783 HydrophobicContact CB-CE1 3.9Å; R728-F783 HydrophobicContact CB-CG 4.33Å; R728-F783 HydrophobicContact CG-CB 3.9Å; R728-F783 HydrophobicContact CG-CD1 3.61Å; R728-F783 HydrophobicContact CG-CE1 4.31Å; R728-F783 HydrophobicContact CG-CG 3.82Å; L768-F783 HydrophobicContact CD2-CZ 4.48Å; M773-F783 HydrophobicContact CE-CE1 4.21Å; M773-F783 HydrophobicContact CE-CZ 3.87Å; C777-F783 HydrophobicContact CB-CD1 4.27Å; C777-F783 HydrophobicContact CB-CE1 4.04Å; C777-F783 HydrophobicContact CB-CZ 4.3Å; G781-F783 WeakPolarHBondContact O-CD2 3.29Å; G781-F783 PolarHBondContact O-N 2.93Å; G781-F783 VanDerWaalsContact O-N 3.08Å
784T89.9Confident91.6Very high40 Ų4025.5 Ų25.525%0.24514%0.14CC..  trans-147.9171179.565.30000111.5K782 A786 S787 D788K782-T784 HydrophobicContact CG-CG2 4.34Å; T784-A786 PolarHBondContact O-N 2.97Å; T784-A786 VanDerWaalsContact O-N 3.16Å; T784-A786 PolarHBondContact OG1-N 3.45Å; T784-S787 PolarHBondContact N-OG 3.34Å; T784-S787 PolarHBondContact O-N 2.9Å; T784-S787 PolarHBondContact O-OG 2.94Å; T784-S787 PolarHBondContact OG1-N 2.68Å; T784-D788 PolarHBondContact O-N 2.88Å
785T94.6Very high91.7Very high46 Ų4625.5 Ų25.528%0.28214%0.14SC..Hα-helixtrans-56.3-29.2169.4-41.40000112.6A721 D788 V789 F861A721-T785 HydrophobicContact CB-CG2 3.59Å; T785-D788 PolarHBondContact O-N 2.72Å; T785-V789 WeakPolarHBondContact O-CG2 3.3Å; T785-V789 PolarHBondContact O-N 3.02Å; T785-F861 HydrophobicContact CG2-CD2 4.12Å; T785-F861 HydrophobicContact CG2-CE2 4.05Å
786A96.6Very high91.9Very high20 Ų2024.8 Ų24.817%0.16514%0.138CC..Hα-helixtrans-74.3-24.7175.900000113.2T784 W790 R858T784-A786 PolarHBondContact O-N 2.97Å; T784-A786 VanDerWaalsContact O-N 3.16Å; T784-A786 PolarHBondContact OG1-N 3.45Å; A786-W790 PolarHBondContact O-N 2.73Å; A786-R858 VanDerWaalsContact O-CD 3.26Å; A786-R858 WeakPolarHBondContact O-CD 3.49Å; A786-R858 PolarHBondContact O-NH1 2.72Å
787S94.7Very high92.4Very high5 Ų525.4 Ų25.44%0.03514%0.14CC..Hα-helixtrans-80.8-30.2169.167.10000112.2C777 T784 V789 W790 A791C777-S787 WeakPolarHBondContact SG-CB 3.36Å; C777-S787 PolarHBondContact SG-OG 3.12Å; T784-S787 PolarHBondContact N-OG 3.34Å; T784-S787 PolarHBondContact O-N 2.9Å; T784-S787 PolarHBondContact O-OG 2.94Å; T784-S787 PolarHBondContact OG1-N 2.68Å; S787-V789 VanDerWaalsContact C-N 3.3Å; S787-W790 WeakPolarHBondContact O-CB 3.24Å; S787-W790 PolarHBondContact O-N 3.29Å; S787-A791 PolarHBondContact O-N 2.95Å
788D97Very high92.8Very high2 Ų225.5 Ų25.51%0.01114%0.14CC..Hα-helixtrans-65.1-34.9169.5-76-8.1000111.4M717 V726 H727 R728 T784 T785 W790 A791 F792 F861M717-D788 HydrophobicContact CE-CB 3.74Å; V726-D788 VanDerWaalsContact CA-OD2 3.3Å; V726-D788 WeakPolarHBondContact CA-OD2 3.43Å; V726-D788 WeakPolarHBondContact CG1-OD1 3.32Å; V726-D788 WeakPolarHBondContact CG1-OD2 3.41Å; H727-D788 PolarHBondContact N-OD1 3.04Å; H727-D788 PolarHBondContact N-OD2 3.25Å; R728-D788 PolarHBondContact N-OD1 3.4Å; T784-D788 PolarHBondContact O-N 2.88Å; T785-D788 PolarHBondContact O-N 2.72Å; D788-W790 VanDerWaalsContact C-N 3.34Å; D788-A791 PolarHBondContact O-N 3.39Å; D788-F792 WeakPolarHBondContact O-CB 3.37Å; D788-F792 PolarHBondContact O-N 3.42Å; D788-F861 HydrophobicContact CB-CE2 4.09Å; D788-F861 HydrophobicContact CB-CZ 4.07Å
789V98.6Very high93.4Very high4 Ų424.5 Ų24.52%0.02414%0.135CC..Hα-helixtrans-62.5-39.2171.6164.20000111.8T785 S787 F792 G793 C850 R858 P859 F861 L864T785-V789 WeakPolarHBondContact O-CG2 3.3Å; T785-V789 PolarHBondContact O-N 3.02Å; S787-V789 VanDerWaalsContact C-N 3.3Å; V789-F792 WeakPolarHBondContact O-CB 3.28Å; V789-F792 PolarHBondContact O-N 3.19Å; V789-G793 PolarHBondContact O-N 3.33Å; V789-C850 HydrophobicContact CG1-CB 4.09Å; V789-C850 WeakPolarHBondContact O-CB 3.28Å; V789-R858 HydrophobicContact CG1-CB 3.86Å; V789-P859 HydrophobicContact CG1-CG 4.31Å; V789-P859 WeakPolarHBondContact CG1-O 3.36Å; V789-P859 WeakPolarHBondContact CG2-O 3.27Å; V789-F861 HydrophobicContact CB-CZ 4.4Å; V789-F861 HydrophobicContact CG2-CD1 4.48Å; V789-F861 HydrophobicContact CG2-CD2 3.93Å; V789-F861 HydrophobicContact CG2-CE1 4.18Å; V789-F861 HydrophobicContact CG2-CE2 3.58Å; V789-F861 HydrophobicContact CG2-CG 4.36Å; V789-F861 HydrophobicContact CG2-CZ 3.72Å; V789-L864 HydrophobicContact CG1-CD1 4.19Å; V789-L864 HydrophobicContact CG2-CD1 4.28Å
790W98.7Very high94.1Very high12 Ų1221.3 Ų21.35%0.04512%0.118CC..Hα-helixtrans-62-48.4173.5-179.2-67.1000111.3M773 A774 A786 S787 D788 F792 G793 V794 F823 C850 W851M773-W790 PolarHBondContact O-NE1 2.71Å; M773-W790 VanDerWaalsContact O-NE1 3.17Å; A774-W790 HydrophobicContact CB-CB 3.79Å; A774-W790 HydrophobicContact CB-CD2 3.66Å; A774-W790 HydrophobicContact CB-CE3 3.91Å; A774-W790 HydrophobicContact CB-CG 3.62Å; A786-W790 PolarHBondContact O-N 2.73Å; S787-W790 WeakPolarHBondContact O-CB 3.24Å; S787-W790 PolarHBondContact O-N 3.29Å; D788-W790 VanDerWaalsContact C-N 3.34Å; W790-F792 VanDerWaalsContact C-N 3.27Å; W790-F792 PolarHBondContact O-N 2.95Å; W790-G793 WeakPolarHBondContact O-CA 3.47Å; W790-G793 PolarHBondContact O-N 2.84Å; W790-V794 PolarHBondContact O-N 2.95Å; W790-V794 VanDerWaalsContact O-N 3.15Å; W790-F823 AromaticContact CH2-CD1 3.73Å; W790-F823 HydrophobicContact CH2-CD1 3.73Å; W790-F823 HydrophobicContact CH2-CD2 4.07Å; W790-F823 AromaticContact CH2-CE1 3.65Å; W790-F823 HydrophobicContact CH2-CE1 3.65Å; W790-F823 HydrophobicContact CH2-CE2 4.02Å; W790-F823 AromaticContact CH2-CG 3.94Å; W790-F823 HydrophobicContact CH2-CG 3.94Å; W790-F823 AromaticContact CH2-CZ 3.81Å; W790-F823 HydrophobicContact CH2-CZ 3.81Å; W790-F823 HydrophobicContact CZ2-CD2 4.43Å; W790-F823 HydrophobicContact CZ2-CE1 4.49Å; W790-F823 HydrophobicContact CZ2-CE2 4.19Å; W790-F823 HydrophobicContact CZ2-CZ 4.22Å; W790-F823 HydrophobicContact CZ3-CD1 4.41Å; W790-F823 HydrophobicContact CZ3-CE1 4.4Å; W790-C850 WeakPolarHBondContact CA-O 3.35Å; W790-W851 AromaticContact CD1-CD1 3.9Å; W790-W851 HydrophobicContact CD2-CB 4.45Å; W790-W851 AromaticContact CD2-CD1 3.61Å; W790-W851 HydrophobicContact CD2-CG 4.39Å; W790-W851 AromaticContact CE2-CD1 3.71Å; W790-W851 HydrophobicContact CE3-CB 4.21Å; W790-W851 AromaticContact CG-CD1 3.73Å; W790-W851 HydrophobicContact CH2-CB 4.2Å; W790-W851 HydrophobicContact CZ2-CB 4.44Å; W790-W851 HydrophobicContact CZ3-CB 4.08Å; W790-W851 WeakPolarHBondContact CZ3-O 3.32Å; W790-W851 AromaticContact NE1-CD1 3.87Å; W790-W851 PolarHBondContact O-NE1 3.33Å
791A98.1Very high94.9Very high4 Ų418.2 Ų18.23%0.03310%0.103CC..Hα-helixtrans-61.9-34.3176.400000112.2L730 W772 S787 D788 V794 T795L730-A791 HydrophobicContact CB-CB 4.09Å; W772-A791 HydrophobicContact CB-CB 4.42Å; W772-A791 WeakPolarHBondContact O-CA 3.39Å; W772-A791 WeakPolarHBondContact O-CB 3.43Å; S787-A791 PolarHBondContact O-N 2.95Å; D788-A791 PolarHBondContact O-N 3.39Å; A791-V794 PolarHBondContact O-N 2.91Å; A791-T795 WeakPolarHBondContact O-CB 3.25Å; A791-T795 PolarHBondContact O-N 2.83Å; A791-T795 PolarHBondContact O-OG1 3.26Å
792F98.7Very high95.7Very high1 Ų117.2 Ų17.20%0.0049%0.089CC..Hα-helixtrans-64.8-39.7170.8178.2-91000112.4I713 A714 L730 D788 V789 W790 V794 T795 L796 F861 L864 L868I713-F792 HydrophobicContact CB-CE2 4.04Å; I713-F792 HydrophobicContact CG2-CD2 3.85Å; I713-F792 HydrophobicContact CG2-CE2 3.8Å; A714-F792 HydrophobicContact CB-CE2 3.9Å; A714-F792 HydrophobicContact CB-CZ 3.84Å; L730-F792 HydrophobicContact CD2-CB 3.78Å; L730-F792 HydrophobicContact CD2-CD2 4.21Å; D788-F792 WeakPolarHBondContact O-CB 3.37Å; D788-F792 PolarHBondContact O-N 3.42Å; V789-F792 WeakPolarHBondContact O-CB 3.28Å; V789-F792 PolarHBondContact O-N 3.19Å; W790-F792 VanDerWaalsContact C-N 3.27Å; W790-F792 PolarHBondContact O-N 2.95Å; F792-V794 VanDerWaalsContact C-N 3.27Å; F792-V794 PolarHBondContact O-N 2.97Å; F792-T795 PolarHBondContact O-N 2.97Å; F792-T795 VanDerWaalsContact O-N 3.17Å; F792-L796 HydrophobicContact CE1-CB 4.37Å; F792-L796 HydrophobicContact CE1-CD2 4.39Å; F792-L796 WeakPolarHBondContact O-CB 3.45Å; F792-L796 PolarHBondContact O-N 2.78Å; F792-F861 HydrophobicContact CB-CE1 3.64Å; F792-F861 HydrophobicContact CB-CZ 4.13Å; F792-F861 HydrophobicContact CD1-CE1 4.46Å; F792-F861 HydrophobicContact CD2-CE1 4.01Å; F792-F861 AromaticContact CG-CE1 3.77Å; F792-F861 HydrophobicContact CG-CE1 3.77Å; F792-L864 HydrophobicContact CD1-CD1 3.69Å; F792-L864 HydrophobicContact CD1-CD2 4.36Å; F792-L864 HydrophobicContact CD1-CG 4.48Å; F792-L864 HydrophobicContact CE1-CB 4.25Å; F792-L864 HydrophobicContact CE1-CD1 4.04Å; F792-L864 HydrophobicContact CE1-CD2 4.16Å; F792-L864 HydrophobicContact CE1-CG 4.39Å; F792-L864 HydrophobicContact CG-CD1 4.4Å; F792-L868 HydrophobicContact CE1-CD1 4.11Å; F792-L868 HydrophobicContact CZ-CD1 3.63Å
793G98.5Very high96.4Very high0 Ų012.9 Ų12.90%07%0.072CC..Hα-helixtrans-56.6-42.2172.300000112V789 W790 W797 W851V789-G793 PolarHBondContact O-N 3.33Å; W790-G793 WeakPolarHBondContact O-CA 3.47Å; W790-G793 PolarHBondContact O-N 2.84Å; G793-W797 PolarHBondContact O-N 3.16Å; G793-W797 VanDerWaalsContact O-N 3.15Å; G793-W851 VanDerWaalsContact C-CZ2 3.44Å; G793-W851 WeakPolarHBondContact O-CZ2 3.29Å
794V98.6Very high96.8Very high1 Ų118.3 Ų18.31%0.0069%0.092CC..Hα-helixtrans-68.3-41.9174.2-176.10000111.5W772 W790 A791 F792 L796 W797 E798 P807 L833 W851W772-V794 HydrophobicContact CD2-CG1 4.29Å; W772-V794 HydrophobicContact CG-CB 4.37Å; W772-V794 HydrophobicContact CG-CG1 3.95Å; W790-V794 PolarHBondContact O-N 2.95Å; W790-V794 VanDerWaalsContact O-N 3.15Å; A791-V794 PolarHBondContact O-N 2.91Å; F792-V794 VanDerWaalsContact C-N 3.27Å; F792-V794 PolarHBondContact O-N 2.97Å; V794-L796 VanDerWaalsContact C-N 3.34Å; V794-L796 PolarHBondContact O-N 2.82Å; V794-W797 WeakPolarHBondContact O-CA 3.5Å; V794-W797 WeakPolarHBondContact O-CB 3.37Å; V794-W797 PolarHBondContact O-N 3.04Å; V794-E798 PolarHBondContact O-N 2.98Å; V794-P807 HydrophobicContact CG1-CB 3.7Å; V794-P807 HydrophobicContact CG1-CG 3.45Å; V794-P807 VanDerWaalsContact CG1-CG 3.45Å; V794-L833 HydrophobicContact CB-CD1 4.41Å; V794-L833 HydrophobicContact CG1-CD1 4.03Å; V794-L833 HydrophobicContact CG2-CD1 4.11Å; V794-W851 HydrophobicContact CG2-CZ2 4.19Å
795T98.4Very high96.9Very high1 Ų118.5 Ų18.51%0.00610%0.097CC..Hα-helixtrans-61.9-40.3177.3-53.20000112.1I713 L730 T732 A791 F792 W797 E798 V799I713-T795 HydrophobicContact CD1-CG2 4.1Å; L730-T795 PolarHBondContact O-OG1 2.87Å; T732-T795 HydrophobicContact CG2-CG2 4.05Å; A791-T795 WeakPolarHBondContact O-CB 3.25Å; A791-T795 PolarHBondContact O-N 2.83Å; A791-T795 PolarHBondContact O-OG1 3.26Å; F792-T795 PolarHBondContact O-N 2.97Å; F792-T795 VanDerWaalsContact O-N 3.17Å; T795-W797 VanDerWaalsContact C-N 3.3Å; T795-W797 PolarHBondContact O-N 3.45Å; T795-E798 WeakPolarHBondContact CA-OE2 3.46Å; T795-E798 WeakPolarHBondContact O-CB 3.26Å; T795-E798 PolarHBondContact O-N 3.48Å; T795-V799 WeakPolarHBondContact O-CG2 3.5Å; T795-V799 PolarHBondContact O-N 3.37Å
796L98.3Very high97Very high3 Ų319.4 Ų19.42%0.01610%0.098CC..Hα-helixtrans-64.7-35.5174-177.368.5000111.5A710 F792 V794 L800 L843 M847 L868A710-L796 HydrophobicContact CB-CD1 3.45Å; A710-L796 VanDerWaalsContact CB-CD1 3.45Å; F792-L796 HydrophobicContact CE1-CB 4.37Å; F792-L796 HydrophobicContact CE1-CD2 4.39Å; F792-L796 WeakPolarHBondContact O-CB 3.45Å; F792-L796 PolarHBondContact O-N 2.78Å; V794-L796 VanDerWaalsContact C-N 3.34Å; V794-L796 PolarHBondContact O-N 2.82Å; L796-L800 WeakPolarHBondContact O-CG 3.31Å; L796-L800 PolarHBondContact O-N 3.46Å; L796-L800 VanDerWaalsContact O-N 3.11Å; L796-L843 HydrophobicContact CD2-CD1 4.05Å; L796-M847 HydrophobicContact CB-CE 4.11Å; L796-M847 HydrophobicContact CD2-CE 3.86Å; L796-M847 HydrophobicContact CD2-CG 3.92Å; L796-M847 HydrophobicContact CG-CE 3.59Å; L796-L868 HydrophobicContact CD1-CD2 4.01Å
797W98.4Very high97Very high14 Ų1418.5 Ų18.55%0.0539%0.091CC..Hα-helixtrans-66.4-44.3173.7-178.996.4000111.5G793 V794 T795 V799 L800 M801 A805 P807 L833 S834 P836 M847 W851G793-W797 PolarHBondContact O-N 3.16Å; G793-W797 VanDerWaalsContact O-N 3.15Å; V794-W797 WeakPolarHBondContact O-CA 3.5Å; V794-W797 WeakPolarHBondContact O-CB 3.37Å; V794-W797 PolarHBondContact O-N 3.04Å; T795-W797 VanDerWaalsContact C-N 3.3Å; T795-W797 PolarHBondContact O-N 3.45Å; W797-V799 VanDerWaalsContact C-N 3.34Å; W797-V799 PolarHBondContact O-N 2.99Å; W797-L800 PolarHBondContact O-N 3.4Å; W797-M801 HydrophobicContact CD2-CG 3.88Å; W797-M801 HydrophobicContact CE3-CG 4.12Å; W797-M801 HydrophobicContact CH2-CE 4.3Å; W797-M801 HydrophobicContact CH2-CG 4.01Å; W797-M801 HydrophobicContact CZ2-CE 4.08Å; W797-M801 HydrophobicContact CZ2-CG 3.75Å; W797-M801 HydrophobicContact CZ2-SD 4.24Å; W797-M801 HydrophobicContact CZ3-CG 4.17Å; W797-M801 WeakPolarHBondContact O-CB 3.47Å; W797-M801 VanDerWaalsContact O-CG 3.25Å; W797-M801 WeakPolarHBondContact O-CG 3.29Å; W797-M801 PolarHBondContact O-N 3.37Å; W797-A805 HydrophobicContact CH2-CB 4.03Å; W797-A805 WeakPolarHBondContact CZ3-O 3.48Å; W797-P807 HydrophobicContact CE3-CB 4.43Å; W797-P807 HydrophobicContact CE3-CG 4.04Å; W797-P807 HydrophobicContact CZ3-CB 4.24Å; W797-P807 HydrophobicContact CZ3-CG 3.9Å; W797-L833 HydrophobicContact CB-CD1 4.17Å; W797-L833 HydrophobicContact CD2-CB 4.3Å; W797-L833 HydrophobicContact CD2-CD1 3.92Å; W797-L833 HydrophobicContact CE3-CD1 4.24Å; W797-L833 HydrophobicContact CG-CB 4.14Å; W797-L833 HydrophobicContact CG-CD1 3.88Å; W797-S834 PolarHBondContact NE1-O 2.98Å; W797-P836 HydrophobicContact CG-CG 4.15Å; W797-M847 HydrophobicContact CB-CE 4.1Å; W797-M847 HydrophobicContact CB-SD 4.44Å; W797-W851 HydrophobicContact CB-CH2 4.47Å
798E98.1Very high97.1Very high4 Ų419 Ų192%0.0199%0.092CC..Hα-helixtrans-56.3-47.2173.5-65.2176.183.400111.6T732 W772 V794 T795 L800 M801 L802 C803 P807T732-E798 WeakPolarHBondContact CB-OE1 3.16Å; T732-E798 HydrophobicContact CG2-CB 3.51Å; T732-E798 HydrophobicContact CG2-CG 4.23Å; T732-E798 PolarHBondContact N-OE2 2.81Å; T732-E798 VanDerWaalsContact N-OE2 3.13Å; T732-E798 PolarHBondContact OG1-OE1 3.43Å; W772-E798 HydrophobicContact CZ2-CG 4.36Å; W772-E798 PolarHBondContact NE1-OE2 3.02Å; V794-E798 PolarHBondContact O-N 2.98Å; T795-E798 WeakPolarHBondContact CA-OE2 3.46Å; T795-E798 WeakPolarHBondContact O-CB 3.26Å; T795-E798 PolarHBondContact O-N 3.48Å; E798-L800 PolarHBondContact O-N 3.5Å; E798-M801 CarbonylContact O-C 3.15Å; E798-M801 PolarHBondContact O-N 3.08Å; E798-M801 VanDerWaalsContact O-N 3.16Å; E798-L802 PolarHBondContact O-N 3.48Å; E798-L802 VanDerWaalsContact O-N 3.1Å; E798-C803 PolarHBondContact O-N 3.32Å; E798-P807 HydrophobicContact CG-CG 4.12Å
799V97.7Very high96.9Very high1 Ų121.2 Ų21.21%0.00612%0.116CC..Hα-helixtrans-59.8-46.3179.8169.70000111.4L672 L676 L706 V709 T732 T795 W797 M801 L802L672-V799 HydrophobicContact CD2-CG2 4.17Å; L676-V799 HydrophobicContact CD1-CB 4.21Å; L676-V799 HydrophobicContact CD1-CG1 4.18Å; L676-V799 HydrophobicContact CD1-CG2 3.98Å; L706-V799 HydrophobicContact CB-CG1 4.14Å; L706-V799 HydrophobicContact CD2-CG1 3.92Å; V709-V799 HydrophobicContact CG1-CG1 4.23Å; V709-V799 HydrophobicContact CG1-CG2 4.28Å; T732-V799 HydrophobicContact CG2-CG2 3.99Å; T795-V799 WeakPolarHBondContact O-CG2 3.5Å; T795-V799 PolarHBondContact O-N 3.37Å; W797-V799 VanDerWaalsContact C-N 3.34Å; W797-V799 PolarHBondContact O-N 2.99Å; V799-M801 VanDerWaalsContact C-N 3.27Å; V799-M801 PolarHBondContact O-N 3.33Å; V799-L802 PolarHBondContact O-N 2.76Å
800L96.3Very high96.7Very high3 Ų326.9 Ų26.92%0.01614%0.142CC..Hα-helixtrans-76.5-11178.9-63.2-178.1000114.2Y703 L706 L796 W797 E798 P836 C839 L843 M847Y703-L800 HydrophobicContact CD2-CD2 4.28Å; Y703-L800 HydrophobicContact CE2-CD2 3.84Å; L706-L800 HydrophobicContact CB-CD2 4.16Å; L706-L800 HydrophobicContact CD1-CD2 4.33Å; L796-L800 WeakPolarHBondContact O-CG 3.31Å; L796-L800 PolarHBondContact O-N 3.46Å; L796-L800 VanDerWaalsContact O-N 3.11Å; W797-L800 PolarHBondContact O-N 3.4Å; E798-L800 PolarHBondContact O-N 3.5Å; L800-P836 HydrophobicContact CB-CB 3.84Å; L800-P836 HydrophobicContact CB-CG 3.94Å; L800-C839 HydrophobicContact CD1-CB 3.65Å; L800-C839 VanDerWaalsContact CD1-SG 3.59Å; L800-L843 HydrophobicContact CD1-CD2 3.63Å; L800-L843 HydrophobicContact CD1-CG 4.34Å; L800-M847 HydrophobicContact CD1-CE 3.7Å
801M95.4Very high96.5Very high46 Ų4628 Ų2823%0.22715%0.149CC..THydrogen-bonded Turntrans-94.64.5167.2-68.6-67.5-69.600112.6W797 E798 V799 C803 R804 A805 P836W797-M801 HydrophobicContact CD2-CG 3.88Å; W797-M801 HydrophobicContact CE3-CG 4.12Å; W797-M801 HydrophobicContact CH2-CE 4.3Å; W797-M801 HydrophobicContact CH2-CG 4.01Å; W797-M801 HydrophobicContact CZ2-CE 4.08Å; W797-M801 HydrophobicContact CZ2-CG 3.75Å; W797-M801 HydrophobicContact CZ2-SD 4.24Å; W797-M801 HydrophobicContact CZ3-CG 4.17Å; W797-M801 WeakPolarHBondContact O-CB 3.47Å; W797-M801 VanDerWaalsContact O-CG 3.25Å; W797-M801 WeakPolarHBondContact O-CG 3.29Å; W797-M801 PolarHBondContact O-N 3.37Å; E798-M801 CarbonylContact O-C 3.15Å; E798-M801 PolarHBondContact O-N 3.08Å; E798-M801 VanDerWaalsContact O-N 3.16Å; V799-M801 VanDerWaalsContact C-N 3.27Å; V799-M801 PolarHBondContact O-N 3.33Å; M801-C803 PolarHBondContact O-N 3.02Å; M801-C803 VanDerWaalsContact O-N 3.14Å; M801-R804 WeakPolarHBondContact O-CB 3.33Å; M801-R804 PolarHBondContact O-N 2.85Å; M801-A805 HydrophobicContact CE-CB 3.93Å; M801-P836 HydrophobicContact CG-CB 4Å; M801-P836 HydrophobicContact CG-CG 3.95Å; M801-P836 HydrophobicContact SD-CB 3.68Å; M801-P836 HydrophobicContact SD-CG 4.1Å
802L95.6Very high96.4Very high13 Ų1331.1 Ų31.17%0.06817%0.167CC..THydrogen-bonded Turntrans50.133.5-173.3-69.678.2000112.6L676 S677 H679 L681 I701 L706 E798 V799 R804L676-L802 CarbonylContact C-O 3.45Å; L676-L802 VanDerWaalsContact C-O 3.3Å; S677-L802 WeakPolarHBondContact CA-O 3.49Å; S677-L802 PolarHBondContact N-O 3.26Å; H679-L802 HydrophobicContact CB-CD2 4.5Å; H679-L802 WeakPolarHBondContact O-CD2 3.43Å; L681-L802 HydrophobicContact CB-CD2 4.47Å; I701-L802 HydrophobicContact CG2-CD2 3.9Å; L706-L802 HydrophobicContact CD1-CD1 4.12Å; E798-L802 PolarHBondContact O-N 3.48Å; E798-L802 VanDerWaalsContact O-N 3.1Å; V799-L802 PolarHBondContact O-N 2.76Å; L802-R804 HydrophobicContact CB-CG 4.33Å; L802-R804 PolarHBondContact O-N 2.99Å; L802-R804 VanDerWaalsContact O-N 3.08Å
803C95.8Very high96Very high15 Ų1532.8 Ų32.810%0.10118%0.177CC..THydrogen-bonded Turntrans56.718.3-175.7-570000115.2L676 E798 M801 A805L676-C803 HydrophobicContact CB-CB 4.34Å; E798-C803 PolarHBondContact O-N 3.32Å; M801-C803 PolarHBondContact O-N 3.02Å; M801-C803 VanDerWaalsContact O-N 3.14Å; C803-A805 VanDerWaalsContact C-N 3.29Å; C803-A805 PolarHBondContact O-N 3.14Å
804R94Very high95.6Very high150 Ų15037.9 Ų37.957%0.56620%0.2SC*.  trans-80.7-1.3-176.8-64.3179172.2-82.3-10.3114.7S677 H679 M801 L802S677-R804 PolarHBondContact O-NH2 2.83Å; H679-R804 PolarHBondContact O-NH2 2.93Å; M801-R804 WeakPolarHBondContact O-CB 3.33Å; M801-R804 PolarHBondContact O-N 2.85Å; L802-R804 HydrophobicContact CB-CG 4.33Å; L802-R804 PolarHBondContact O-N 2.99Å; L802-R804 VanDerWaalsContact O-N 3.08Å
805A93.6Very high95.4Very high43 Ų4341.9 Ų41.936%0.35522%0.219SC..SBendtrans-148142.5178.300000110.7W797 M801 C803W797-A805 HydrophobicContact CH2-CB 4.03Å; W797-A805 WeakPolarHBondContact CZ3-O 3.48Å; M801-A805 HydrophobicContact CE-CB 3.93Å; C803-A805 VanDerWaalsContact C-N 3.29Å; C803-A805 PolarHBondContact O-N 3.14Å
806Q94.8Very high95.2Very high65 Ų6542.1 Ų42.130%0.30422%0.221SC..  trans-74.4140.6172.4-165.6-173.749.600110.2G757 D758 W772 F808 G809G757-Q806 PolarHBondContact O-NE2 2.9Å; D758-Q806 PolarHBondContact OD1-NE2 2.97Å; W772-Q806 HydrophobicContact CH2-CG 4.45Å; Q806-F808 PolarHBondContact O-N 3.29Å; Q806-G809 PolarHBondContact O-N 2.9Å
807P97.6Very high94.8Very high1 Ų144.4 Ų44.41%0.00623%0.232CC..THydrogen-bonded Turntrans-55.5130.1170.8-2534.5000111.6R771 W772 V794 W797 E798 G809 L833R771-P807 HydrophobicContact CB-CB 4.35Å; R771-P807 PolarHBondContact NH1-O 3.08Å; W772-P807 HydrophobicContact CH2-CG 4.02Å; W772-P807 HydrophobicContact CZ2-CG 3.64Å; V794-P807 HydrophobicContact CG1-CB 3.7Å; V794-P807 HydrophobicContact CG1-CG 3.45Å; V794-P807 VanDerWaalsContact CG1-CG 3.45Å; W797-P807 HydrophobicContact CE3-CB 4.43Å; W797-P807 HydrophobicContact CE3-CG 4.04Å; W797-P807 HydrophobicContact CZ3-CB 4.24Å; W797-P807 HydrophobicContact CZ3-CG 3.9Å; E798-P807 HydrophobicContact CG-CG 4.12Å; P807-G809 PolarHBondContact O-N 3.08Å; P807-L833 HydrophobicContact CB-CD1 4.08Å; P807-L833 HydrophobicContact CB-CD2 3.98Å
808F96.8Very high94.5Very high15 Ų1549.5 Ų49.57%0.06626%0.256CS..THydrogen-bonded Turntrans53.931.2-172.8-53.8-76.3000114.3R771 Q806 Q810 L811 V816 V831 L833R771-F808 PolarHBondContact NH1-O 3.02Å; Q806-F808 PolarHBondContact O-N 3.29Å; F808-Q810 VanDerWaalsContact C-OE1 3.27Å; F808-Q810 PolarHBondContact O-N 2.93Å; F808-L811 HydrophobicContact CB-CB 4.34Å; F808-L811 HydrophobicContact CB-CD1 4.18Å; F808-L811 HydrophobicContact CB-CG 4.38Å; F808-L811 HydrophobicContact CD1-CD1 4.06Å; F808-L811 HydrophobicContact CG-CD1 4.44Å; F808-L811 WeakPolarHBondContact O-CB 3.1Å; F808-L811 PolarHBondContact O-N 3.36Å; F808-V816 HydrophobicContact CB-CG2 3.88Å; F808-V816 HydrophobicContact CG-CG2 4.4Å; F808-V831 HydrophobicContact CE1-CG1 4.49Å; F808-V831 WeakPolarHBondContact CE1-O 3.45Å; F808-L833 HydrophobicContact CB-CD2 4.45Å; F808-L833 HydrophobicContact CD1-CD2 3.67Å; F808-L833 HydrophobicContact CD1-CG 4.47Å; F808-L833 HydrophobicContact CD2-CD2 3.69Å; F808-L833 HydrophobicContact CD2-CG 4.4Å; F808-L833 HydrophobicContact CE1-CD2 3.7Å; F808-L833 HydrophobicContact CE1-CG 3.99Å; F808-L833 HydrophobicContact CE2-CD1 4.42Å; F808-L833 HydrophobicContact CE2-CD2 3.73Å; F808-L833 HydrophobicContact CE2-CG 3.93Å; F808-L833 HydrophobicContact CG-CD2 3.66Å; F808-L833 HydrophobicContact CZ-CD2 3.74Å; F808-L833 HydrophobicContact CZ-CG 3.71Å
809G93.5Very high94.4Very high50 Ų5049.9 Ų49.952%0.51526%0.259SS..THydrogen-bonded Turntrans-58.7-11.9-177.600000115.8Q806 P807Q806-G809 PolarHBondContact O-N 2.9Å; P807-G809 PolarHBondContact O-N 3.08Å
810Q93.2Very high94.1Very high122 Ų12250.1 Ų50.157%0.5726%0.261SS*.THydrogen-bonded Turntrans-84.9-3.6170.578.1-74.63.200114.7F808F808-Q810 VanDerWaalsContact C-OE1 3.27Å; F808-Q810 PolarHBondContact O-N 2.93Å
811L95.1Very high93.7Very high36 Ų3650.4 Ų50.419%0.18827%0.265CS..SBendtrans-117.8144.2-178.8-58.3-175.5000110.9R771 F808 Q815 V816R771-L811 PolarHBondContact NH1-O 3.4Å; R771-L811 PolarHBondContact NH2-O 2.91Å; F808-L811 HydrophobicContact CB-CB 4.34Å; F808-L811 HydrophobicContact CB-CD1 4.18Å; F808-L811 HydrophobicContact CB-CG 4.38Å; F808-L811 HydrophobicContact CD1-CD1 4.06Å; F808-L811 HydrophobicContact CG-CD1 4.44Å; F808-L811 WeakPolarHBondContact O-CB 3.1Å; F808-L811 PolarHBondContact O-N 3.36Å; L811-Q815 HydrophobicContact CB-CB 3.94Å; L811-Q815 HydrophobicContact CD2-CB 4.41Å; L811-V816 HydrophobicContact CB-CG2 4.1Å
812T95.4Very high93.6Very high69 Ų6949.1 Ų49.142%0.42326%0.258SS..  trans-70.6166.5167.983.60000111.3E814 Q815 V816T812-E814 VanDerWaalsContact C-N 3.28Å; T812-E814 WeakPolarHBondContact CB-OE2 3.35Å; T812-E814 PolarHBondContact O-N 3.3Å; T812-E814 PolarHBondContact OG1-N 3.46Å; T812-E814 PolarHBondContact OG1-OE2 2.91Å; T812-Q815 WeakPolarHBondContact O-CB 3.33Å; T812-Q815 PolarHBondContact O-N 3.31Å; T812-Q815 VanDerWaalsContact O-N 3.12Å; T812-Q815 PolarHBondContact OG1-N 2.92Å; T812-V816 WeakPolarHBondContact O-CG2 3.49Å; T812-V816 PolarHBondContact O-N 3.48Å
813D91Very high93.4Very high37 Ų3748.8 Ų48.820%0.19826%0.256CS..Hα-helixtrans-62.9-35.8178.7-72.6-10.4000112.1Y760 I770 R771 V816 I817Y760-D813 HydrophobicContact CD2-CB 3.45Å; Y760-D813 VanDerWaalsContact CD2-CB 3.45Å; Y760-D813 WeakPolarHBondContact CD2-OD2 3.39Å; Y760-D813 HydrophobicContact CE2-CB 3.76Å; Y760-D813 HydrophobicContact CG-CB 4.13Å; I770-D813 HydrophobicContact CD1-CB 3.68Å; I770-D813 WeakPolarHBondContact CD1-O 3.4Å; R771-D813 IonicContact CZ-OD1 3.84Å; R771-D813 VanDerWaalsContact CZ-OD1 3.3Å; R771-D813 IonicContact NE-OD1 2.64Å; R771-D813 PolarHBondContact NE-OD1 2.95Å; R771-D813 IonicContact NH2-OD1 2.74Å; R771-D813 PolarHBondContact NH2-OD1 3.33Å; D813-V816 PolarHBondContact O-N 3.31Å; D813-I817 WeakPolarHBondContact O-CG1 3.44Å; D813-I817 PolarHBondContact O-N 2.95Å
814E90.4Very high93.1Very high106 Ų10653.2 Ų53.250%0.49527%0.274SS..Hα-helixtrans-63.8-39.9172.6-59.170.6-153.800111.6T812 V816 I817 E818T812-E814 VanDerWaalsContact C-N 3.28Å; T812-E814 WeakPolarHBondContact CB-OE2 3.35Å; T812-E814 PolarHBondContact O-N 3.3Å; T812-E814 PolarHBondContact OG1-N 3.46Å; T812-E814 PolarHBondContact OG1-OE2 2.91Å; E814-V816 VanDerWaalsContact C-N 3.35Å; E814-I817 PolarHBondContact O-N 3.49Å; E814-E818 PolarHBondContact O-N 2.9Å
815Q93.9Very high92.8Very high86 Ų8649.2 Ų49.240%0.40226%0.259SS..Hα-helixtrans-70.1-30.5176.3-69.2177.9-38.300112.4L811 T812 E818 N819L811-Q815 HydrophobicContact CB-CB 3.94Å; L811-Q815 HydrophobicContact CD2-CB 4.41Å; T812-Q815 WeakPolarHBondContact O-CB 3.33Å; T812-Q815 PolarHBondContact O-N 3.31Å; T812-Q815 VanDerWaalsContact O-N 3.12Å; T812-Q815 PolarHBondContact OG1-N 2.92Å; Q815-E818 PolarHBondContact O-N 2.9Å; Q815-N819 VanDerWaalsContact O-CB 3.32Å; Q815-N819 WeakPolarHBondContact O-CB 3.04Å; Q815-N819 PolarHBondContact O-N 3.3Å
816V94.1Very high92.6Very high6 Ų651.4 Ų51.44%0.03626%0.264CS..Hα-helixtrans-67.2-37.5170.5171.80000110.8I770 R771 F808 L811 T812 D813 E814 N819 A820I770-V816 HydrophobicContact CB-CG1 4.43Å; I770-V816 HydrophobicContact CD1-CB 4.15Å; I770-V816 HydrophobicContact CD1-CG1 4.05Å; I770-V816 HydrophobicContact CG1-CG1 4.18Å; R771-V816 HydrophobicContact CG-CG1 4.24Å; R771-V816 HydrophobicContact CG-CG2 4.19Å; F808-V816 HydrophobicContact CB-CG2 3.88Å; F808-V816 HydrophobicContact CG-CG2 4.4Å; L811-V816 HydrophobicContact CB-CG2 4.1Å; T812-V816 WeakPolarHBondContact O-CG2 3.49Å; T812-V816 PolarHBondContact O-N 3.48Å; D813-V816 PolarHBondContact O-N 3.31Å; E814-V816 VanDerWaalsContact C-N 3.35Å; V816-N819 PolarHBondContact O-N 2.91Å; V816-A820 PolarHBondContact O-N 3.19Å; V816-A820 VanDerWaalsContact O-N 3.16Å
817I90.8Very high92.4Very high51 Ų5153.9 Ų53.926%0.26228%0.276SS..Hα-helixtrans-69.6-40.1173.7-65.9163.8000111.4Y760 I770 I778 D813 E814 N819 A820 G821Y760-I817 HydrophobicContact CD1-CD1 3.74Å; Y760-I817 HydrophobicContact CE1-CD1 3.37Å; I770-I817 HydrophobicContact CD1-CD1 4.17Å; I770-I817 HydrophobicContact CD1-CG1 4.01Å; I778-I817 HydrophobicContact CG2-CG1 4.16Å; I778-I817 HydrophobicContact CG2-CG2 4.23Å; D813-I817 WeakPolarHBondContact O-CG1 3.44Å; D813-I817 PolarHBondContact O-N 2.95Å; E814-I817 PolarHBondContact O-N 3.49Å; I817-N819 VanDerWaalsContact C-N 3.34Å; I817-N819 PolarHBondContact O-N 3.49Å; I817-A820 WeakPolarHBondContact O-CB 3.45Å; I817-A820 PolarHBondContact O-N 2.98Å; I817-G821 PolarHBondContact O-N 2.83Å; I817-G821 VanDerWaalsContact O-N 3.16Å
818E91.9Very high92Very high120 Ų12057.2 Ų57.256%0.56131%0.31SS*.Hα-helixtrans-62.6-40.6173.2-177.7170.3-148.900111.8E814 Q815 A820 G821 E822E814-E818 PolarHBondContact O-N 2.9Å; Q815-E818 PolarHBondContact O-N 2.9Å; E818-A820 VanDerWaalsContact C-N 3.32Å; E818-A820 PolarHBondContact O-N 3.22Å; E818-G821 CarbonylContact O-C 3.6Å; E818-G821 VanDerWaalsContact O-CA 3.24Å; E818-G821 WeakPolarHBondContact O-CA 3.33Å; E818-G821 PolarHBondContact O-N 3.39Å; E818-E822 PolarHBondContact O-N 2.93Å
819N94.7Very high91.9Very high13 Ų1362.4 Ų62.47%0.0733%0.329CS..Hα-helixtrans-60.1-39.8175.2-170.929.7000112Q815 V816 I817 G821 E822 F823 V831Q815-N819 VanDerWaalsContact O-CB 3.32Å; Q815-N819 WeakPolarHBondContact O-CB 3.04Å; Q815-N819 PolarHBondContact O-N 3.3Å; V816-N819 PolarHBondContact O-N 2.91Å; I817-N819 VanDerWaalsContact C-N 3.34Å; I817-N819 PolarHBondContact O-N 3.49Å; N819-G821 VanDerWaalsContact C-N 3.26Å; N819-G821 PolarHBondContact O-N 3.03Å; N819-E822 PolarHBondContact O-N 3.43Å; N819-F823 WeakPolarHBondContact O-CD2 3.28Å; N819-F823 PolarHBondContact O-N 3.23Å; N819-V831 PolarHBondContact ND2-O 3.25Å; N819-V831 PolarHBondContact OD1-N 2.84Å
820A92.1Very high91.9Very high5 Ų561.2 Ų61.24%0.04131%0.311CS..Hα-helixtrans-61.4-35171.200000112.3W775 I778 V816 I817 E818 E822 F823 F824W775-A820 HydrophobicContact CB-CB 4.17Å; I778-A820 HydrophobicContact CB-CB 4.13Å; I778-A820 HydrophobicContact CD1-CB 3.75Å; I778-A820 HydrophobicContact CG2-CB 4.12Å; V816-A820 PolarHBondContact O-N 3.19Å; V816-A820 VanDerWaalsContact O-N 3.16Å; I817-A820 WeakPolarHBondContact O-CB 3.45Å; I817-A820 PolarHBondContact O-N 2.98Å; E818-A820 VanDerWaalsContact C-N 3.32Å; E818-A820 PolarHBondContact O-N 3.22Å; A820-E822 VanDerWaalsContact C-N 3.35Å; A820-F823 PolarHBondContact O-N 2.9Å; A820-F824 PolarHBondContact O-N 2.8Å; A820-F824 VanDerWaalsContact O-N 3.1Å
821G87.4Confident92Very high10 Ų1058.3 Ų58.310%0.10330%0.301CS..Hα-helixtrans-61-38.2168.600000113.5I817 E818 N819 F824 R825I817-G821 PolarHBondContact O-N 2.83Å; I817-G821 VanDerWaalsContact O-N 3.16Å; E818-G821 CarbonylContact O-C 3.6Å; E818-G821 VanDerWaalsContact O-CA 3.24Å; E818-G821 WeakPolarHBondContact O-CA 3.33Å; E818-G821 PolarHBondContact O-N 3.39Å; N819-G821 VanDerWaalsContact C-N 3.26Å; N819-G821 PolarHBondContact O-N 3.03Å; G821-F824 PolarHBondContact O-N 2.83Å; G821-R825 WeakPolarHBondContact O-CB 3.31Å; G821-R825 WeakPolarHBondContact O-CD 3.38Å; G821-R825 WeakPolarHBondContact O-CG 3.25Å; G821-R825 PolarHBondContact O-N 2.7Å
822E93.5Very high92.1Very high19 Ų1960.3 Ų60.39%0.08931%0.307CS..Hα-helixtrans-72.5-36.2175.4-70.1-57.6153.300113.5E818 N819 A820 F824 R825 D826 R829 Q830E818-E822 PolarHBondContact O-N 2.93Å; N819-E822 PolarHBondContact O-N 3.43Å; A820-E822 VanDerWaalsContact C-N 3.35Å; E822-F824 VanDerWaalsContact C-N 3.27Å; E822-F824 PolarHBondContact O-N 3.25Å; E822-R825 PolarHBondContact O-N 3.16Å; E822-R825 VanDerWaalsContact OE1-CD 3.28Å; E822-R825 WeakPolarHBondContact OE1-CD 3.38Å; E822-R825 IonicContact OE1-CZ 3.66Å; E822-R825 IonicContact OE1-NE 2.9Å; E822-R825 IonicContact OE1-NH1 3.26Å; E822-R825 PolarHBondContact OE1-NH1 2.92Å; E822-D826 PolarHBondContact O-N 2.83Å; E822-R829 HydrophobicContact CB-CB 4.44Å; E822-R829 VanDerWaalsContact CD-NE 3.3Å; E822-R829 VanDerWaalsContact CD-NH2 3.3Å; E822-R829 HydrophobicContact CG-CB 4.07Å; E822-R829 IonicContact OE1-CZ 2.9Å; E822-R829 IonicContact OE1-NE 3.31Å; E822-R829 PolarHBondContact OE1-NE 2.9Å; E822-R829 IonicContact OE1-NH2 2.71Å; E822-R829 PolarHBondContact OE1-NH2 2.85Å; E822-R829 IonicContact OE2-CZ 2.97Å; E822-R829 IonicContact OE2-NE 2.71Å; E822-R829 PolarHBondContact OE2-NE 3.1Å; E822-R829 IonicContact OE2-NH2 3.12Å; E822-R829 PolarHBondContact OE2-NH2 2.91Å; E822-Q830 HydrophobicContact CB-CB 4.23Å
823F92.3Very high92.3Very high6 Ų657.2 Ų57.23%0.02629%0.287CS..Hα-helixtrans-58.7-38.3168-85.4-76.9000112.3W775 W790 N819 A820 Q830 Y832 R853W775-F823 HydrophobicContact CB-CB 3.77Å; W775-F823 HydrophobicContact CG-CB 3.95Å; W790-F823 AromaticContact CH2-CD1 3.73Å; W790-F823 HydrophobicContact CH2-CD1 3.73Å; W790-F823 HydrophobicContact CH2-CD2 4.07Å; W790-F823 AromaticContact CH2-CE1 3.65Å; W790-F823 HydrophobicContact CH2-CE1 3.65Å; W790-F823 HydrophobicContact CH2-CE2 4.02Å; W790-F823 AromaticContact CH2-CG 3.94Å; W790-F823 HydrophobicContact CH2-CG 3.94Å; W790-F823 AromaticContact CH2-CZ 3.81Å; W790-F823 HydrophobicContact CH2-CZ 3.81Å; W790-F823 HydrophobicContact CZ2-CD2 4.43Å; W790-F823 HydrophobicContact CZ2-CE1 4.49Å; W790-F823 HydrophobicContact CZ2-CE2 4.19Å; W790-F823 HydrophobicContact CZ2-CZ 4.22Å; W790-F823 HydrophobicContact CZ3-CD1 4.41Å; W790-F823 HydrophobicContact CZ3-CE1 4.4Å; N819-F823 WeakPolarHBondContact O-CD2 3.28Å; N819-F823 PolarHBondContact O-N 3.23Å; A820-F823 PolarHBondContact O-N 2.9Å; F823-Q830 HydrophobicContact CD1-CB 4.02Å; F823-Q830 HydrophobicContact CD1-CG 4.03Å; F823-Q830 HydrophobicContact CD2-CB 3.87Å; F823-Q830 HydrophobicContact CE1-CB 4.09Å; F823-Q830 HydrophobicContact CE1-CG 3.94Å; F823-Q830 HydrophobicContact CE2-CB 3.93Å; F823-Q830 HydrophobicContact CG-CB 3.91Å; F823-Q830 HydrophobicContact CG-CG 4.43Å; F823-Q830 HydrophobicContact CZ-CB 4.04Å; F823-Q830 HydrophobicContact CZ-CG 4.23Å; F823-Y832 HydrophobicContact CE1-CD1 4.18Å; F823-Y832 AromaticContact CE1-CE1 3.47Å; F823-Y832 HydrophobicContact CE1-CE1 3.47Å; F823-Y832 VanDerWaalsContact CE1-CE1 3.47Å; F823-Y832 HydrophobicContact CE1-CE2 4.48Å; F823-Y832 AromaticContact CE1-CZ 3.64Å; F823-Y832 AromaticContact CZ-CD1 3.84Å; F823-Y832 HydrophobicContact CZ-CD1 3.84Å; F823-Y832 AromaticContact CZ-CE1 3.62Å; F823-Y832 HydrophobicContact CZ-CE1 3.62Å; F823-Y832 HydrophobicContact CZ-CE2 4.49Å; F823-Y832 HydrophobicContact CZ-CG 4.39Å; F823-Y832 AromaticContact CZ-CZ 3.96Å; F823-R853 WeakPolarHBondContact O-CD 3.25Å; F823-R853 WeakPolarHBondContact O-CG 3.37Å; F823-R853 PolarHBondContact O-NE 2.89Å; F823-R853 VanDerWaalsContact O-NE 3.15Å
824F88.4Confident92.5Very high107 Ų10759.5 Ų59.547%0.46931%0.306SS..Hα-helixtrans-69.1-41.1173.1174.3-115000112.7W775 L779 A820 G821 E822 D826 R853W775-F824 HydrophobicContact CE3-CB 3.85Å; W775-F824 HydrophobicContact CE3-CD2 4.16Å; W775-F824 HydrophobicContact CE3-CG 4.4Å; W775-F824 AromaticContact CH2-CD2 3.73Å; W775-F824 HydrophobicContact CH2-CD2 3.73Å; W775-F824 HydrophobicContact CH2-CE2 4.41Å; W775-F824 HydrophobicContact CZ3-CB 4Å; W775-F824 AromaticContact CZ3-CD2 3.41Å; W775-F824 HydrophobicContact CZ3-CD2 3.41Å; W775-F824 VanDerWaalsContact CZ3-CD2 3.41Å; W775-F824 HydrophobicContact CZ3-CE2 4.26Å; W775-F824 HydrophobicContact CZ3-CG 4.05Å; L779-F824 HydrophobicContact CD1-CB 3.68Å; L779-F824 HydrophobicContact CD1-CD1 4.49Å; L779-F824 HydrophobicContact CD1-CG 4.17Å; A820-F824 PolarHBondContact O-N 2.8Å; A820-F824 VanDerWaalsContact O-N 3.1Å; G821-F824 PolarHBondContact O-N 2.83Å; E822-F824 VanDerWaalsContact C-N 3.27Å; E822-F824 PolarHBondContact O-N 3.25Å; F824-D826 VanDerWaalsContact C-N 3.35Å; F824-R853 PolarHBondContact O-NE 3.32Å; F824-R853 PolarHBondContact O-NH2 2.79Å
825R88.5Confident92.9Very high66 Ų6660 Ų6025%0.24930%0.304CS..Hα-helixtrans-68.9-29.3-179.7-72.9162.2-177.5156.96.5113.9G821 E822 Q827G821-R825 WeakPolarHBondContact O-CB 3.31Å; G821-R825 WeakPolarHBondContact O-CD 3.38Å; G821-R825 WeakPolarHBondContact O-CG 3.25Å; G821-R825 PolarHBondContact O-N 2.7Å; E822-R825 PolarHBondContact O-N 3.16Å; E822-R825 VanDerWaalsContact OE1-CD 3.28Å; E822-R825 WeakPolarHBondContact OE1-CD 3.38Å; E822-R825 IonicContact OE1-CZ 3.66Å; E822-R825 IonicContact OE1-NE 2.9Å; E822-R825 IonicContact OE1-NH1 3.26Å; E822-R825 PolarHBondContact OE1-NH1 2.92Å; R825-Q827 WeakPolarHBondContact O-CG 3Å; R825-Q827 PolarHBondContact O-NE2 2.76Å
826D90Very high92.9Very high89 Ų8956 Ų5648%0.47629%0.285SS..THydrogen-bonded Turntrans48.355.8-179.2-156.219.8000114.9E822 F824 Q830E822-D826 PolarHBondContact O-N 2.83Å; F824-D826 VanDerWaalsContact C-N 3.35Å; D826-Q830 PolarHBondContact OD1-NE2 3.48Å
827Q89.8Confident92.7Very high118 Ų11861.3 Ų61.355%0.55132%0.32SS*.SBendtrans-116.421.4-175.6-75.4162.636.300113R825 R829R825-Q827 WeakPolarHBondContact O-CG 3Å; R825-Q827 PolarHBondContact O-NE2 2.76Å; Q827-R829 PolarHBondContact O-N 2.85Å; Q827-R829 VanDerWaalsContact OE1-CZ 3.3Å
828G90Very high92.3Very high70 Ų7060 Ų6072%0.72232%0.317SS*.SBendtrans69.215.2179.500000114.6Q830G828-Q830 VanDerWaalsContact CA-OE1 3.3Å
829R93.1Very high92.3Very high125 Ų12554.3 Ų54.347%0.47229%0.29SS..  trans-99.8-8.7176.2-64.3-170.2-60.5-86.5-7.2113.2E822 Q827E822-R829 HydrophobicContact CB-CB 4.44Å; E822-R829 VanDerWaalsContact CD-NE 3.3Å; E822-R829 VanDerWaalsContact CD-NH2 3.3Å; E822-R829 HydrophobicContact CG-CB 4.07Å; E822-R829 IonicContact OE1-CZ 2.9Å; E822-R829 IonicContact OE1-NE 3.31Å; E822-R829 PolarHBondContact OE1-NE 2.9Å; E822-R829 IonicContact OE1-NH2 2.71Å; E822-R829 PolarHBondContact OE1-NH2 2.85Å; E822-R829 IonicContact OE2-CZ 2.97Å; E822-R829 IonicContact OE2-NE 2.71Å; E822-R829 PolarHBondContact OE2-NE 3.1Å; E822-R829 IonicContact OE2-NH2 3.12Å; E822-R829 PolarHBondContact OE2-NH2 2.91Å; Q827-R829 PolarHBondContact O-N 2.85Å; Q827-R829 VanDerWaalsContact OE1-CZ 3.3Å
830Q94.4Very high92.2Very high25 Ų2556.3 Ų56.312%0.11730%0.304CS..PPolyproline II helixtrans-63.5135.6176.961-91.939.100111.6E822 F823 D826 G828 Y832E822-Q830 HydrophobicContact CB-CB 4.23Å; F823-Q830 HydrophobicContact CD1-CB 4.02Å; F823-Q830 HydrophobicContact CD1-CG 4.03Å; F823-Q830 HydrophobicContact CD2-CB 3.87Å; F823-Q830 HydrophobicContact CE1-CB 4.09Å; F823-Q830 HydrophobicContact CE1-CG 3.94Å; F823-Q830 HydrophobicContact CE2-CB 3.93Å; F823-Q830 HydrophobicContact CG-CB 3.91Å; F823-Q830 HydrophobicContact CG-CG 4.43Å; F823-Q830 HydrophobicContact CZ-CB 4.04Å; F823-Q830 HydrophobicContact CZ-CG 4.23Å; D826-Q830 PolarHBondContact OD1-NE2 3.48Å; G828-Q830 VanDerWaalsContact CA-OE1 3.3Å; Q830-Y832 HydrophobicContact CG-CE2 3.73Å
831V96Very high92.1Very high61 Ų6160.9 Ų60.937%0.3732%0.324SS..PPolyproline II helixtrans-100.8125.4-179.7-178.50000109.2F808 N819F808-V831 HydrophobicContact CE1-CG1 4.49Å; F808-V831 WeakPolarHBondContact CE1-O 3.45Å; N819-V831 PolarHBondContact ND2-O 3.25Å; N819-V831 PolarHBondContact OD1-N 2.84Å
832Y97.3Very high92.3Very high78 Ų7862 Ų6231%0.30634%0.336SS..PPolyproline II helixtrans-96.4160.2173.3-61.7-91.9000110.8F823 Q830 S834 L848 W851F823-Y832 HydrophobicContact CE1-CD1 4.18Å; F823-Y832 AromaticContact CE1-CE1 3.47Å; F823-Y832 HydrophobicContact CE1-CE1 3.47Å; F823-Y832 VanDerWaalsContact CE1-CE1 3.47Å; F823-Y832 HydrophobicContact CE1-CE2 4.48Å; F823-Y832 AromaticContact CE1-CZ 3.64Å; F823-Y832 AromaticContact CZ-CD1 3.84Å; F823-Y832 HydrophobicContact CZ-CD1 3.84Å; F823-Y832 AromaticContact CZ-CE1 3.62Å; F823-Y832 HydrophobicContact CZ-CE1 3.62Å; F823-Y832 HydrophobicContact CZ-CE2 4.49Å; F823-Y832 HydrophobicContact CZ-CG 4.39Å; F823-Y832 AromaticContact CZ-CZ 3.96Å; Q830-Y832 HydrophobicContact CG-CE2 3.73Å; Y832-S834 PolarHBondContact O-N 2.81Å; Y832-L848 HydrophobicContact CD1-CD2 3.75Å; Y832-L848 HydrophobicContact CE1-CD2 4.32Å; Y832-L848 HydrophobicContact CG-CD2 3.92Å; Y832-W851 HydrophobicContact CD1-CB 4.13Å; Y832-W851 HydrophobicContact CD1-CE3 4.02Å; Y832-W851 HydrophobicContact CE1-CB 4.07Å
833L97.8Very high92.3Very high3 Ų361.3 Ų61.32%0.01633%0.333CS..PPolyproline II helixtrans-69.3127.4171.4-64.7173000110.1V794 W797 P807 F808 Y844 W851V794-L833 HydrophobicContact CB-CD1 4.41Å; V794-L833 HydrophobicContact CG1-CD1 4.03Å; V794-L833 HydrophobicContact CG2-CD1 4.11Å; W797-L833 HydrophobicContact CB-CD1 4.17Å; W797-L833 HydrophobicContact CD2-CB 4.3Å; W797-L833 HydrophobicContact CD2-CD1 3.92Å; W797-L833 HydrophobicContact CE3-CD1 4.24Å; W797-L833 HydrophobicContact CG-CB 4.14Å; W797-L833 HydrophobicContact CG-CD1 3.88Å; P807-L833 HydrophobicContact CB-CD1 4.08Å; P807-L833 HydrophobicContact CB-CD2 3.98Å; F808-L833 HydrophobicContact CB-CD2 4.45Å; F808-L833 HydrophobicContact CD1-CD2 3.67Å; F808-L833 HydrophobicContact CD1-CG 4.47Å; F808-L833 HydrophobicContact CD2-CD2 3.69Å; F808-L833 HydrophobicContact CD2-CG 4.4Å; F808-L833 HydrophobicContact CE1-CD2 3.7Å; F808-L833 HydrophobicContact CE1-CG 3.99Å; F808-L833 HydrophobicContact CE2-CD1 4.42Å; F808-L833 HydrophobicContact CE2-CD2 3.73Å; F808-L833 HydrophobicContact CE2-CG 3.93Å; F808-L833 HydrophobicContact CG-CD2 3.66Å; F808-L833 HydrophobicContact CZ-CD2 3.74Å; F808-L833 HydrophobicContact CZ-CG 3.71Å; L833-Y844 WeakPolarHBondContact O-CE2 3.27Å; L833-Y844 PolarHBondContact O-OH 2.81Å; L833-Y844 VanDerWaalsContact O-OH 3.14Å; L833-W851 HydrophobicContact CB-CH2 3.76Å; L833-W851 HydrophobicContact CB-CZ2 4.44Å; L833-W851 HydrophobicContact CB-CZ3 4.16Å; L833-W851 HydrophobicContact CD1-CH2 3.93Å; L833-W851 HydrophobicContact CD1-CZ2 3.79Å; L833-W851 HydrophobicContact CG-CH2 4.24Å; L833-W851 HydrophobicContact CG-CZ2 4.45Å
834S96.7Very high92.6Very high86 Ų8662.8 Ų62.860%0.60134%0.339SS*.PPolyproline II helixtrans-58.4141.7-179.5-53.80000112.8W797 Y832 P836W797-S834 PolarHBondContact NE1-O 2.98Å; Y832-S834 PolarHBondContact O-N 2.81Å; S834-P836 WeakPolarHBondContact O-CD 3.32Å
835R97.3Very high92.9Very high116 Ų11662.3 Ų62.344%0.43834%0.338SS..PPolyproline II helixtrans-52.4120.6176.9-174.217468.470.24.7111.5C839 Y844R835-C839 WeakPolarHBondContact CD-O 3.37Å; R835-C839 HydrophobicContact CG-CB 4.04Å; R835-C839 PolarHBondContact NH1-O 3.12Å; R835-Y844 VanDerWaalsContact CA-CE2 3.47Å; R835-Y844 HydrophobicContact CB-CD1 3.92Å; R835-Y844 HydrophobicContact CB-CD2 3.66Å; R835-Y844 HydrophobicContact CB-CE1 4.01Å; R835-Y844 HydrophobicContact CB-CE2 3.77Å; R835-Y844 HydrophobicContact CB-CG 3.73Å; R835-Y844 HydrophobicContact CG-CD1 4.13Å; R835-Y844 HydrophobicContact CG-CD2 3.85Å; R835-Y844 HydrophobicContact CG-CE2 4.47Å; R835-Y844 HydrophobicContact CG-CG 3.65Å
836P94.6Very high93.3Very high1 Ų159.5 Ų59.51%0.00633%0.328CS..PPolyproline II helixtrans-58.3147.5175.2-26.535.2000111.9W797 L800 M801 S834 A838 C839 M847W797-P836 HydrophobicContact CG-CG 4.15Å; L800-P836 HydrophobicContact CB-CB 3.84Å; L800-P836 HydrophobicContact CB-CG 3.94Å; M801-P836 HydrophobicContact CG-CB 4Å; M801-P836 HydrophobicContact CG-CG 3.95Å; M801-P836 HydrophobicContact SD-CB 3.68Å; M801-P836 HydrophobicContact SD-CG 4.1Å; S834-P836 WeakPolarHBondContact O-CD 3.32Å; P836-A838 PolarHBondContact O-N 2.97Å; P836-C839 HydrophobicContact CB-CB 3.88Å; P836-C839 HydrophobicContact CG-CB 4.08Å; P836-C839 WeakPolarHBondContact O-CB 3.5Å; P836-C839 PolarHBondContact O-N 2.85Å; P836-M847 HydrophobicContact CG-CE 4.49Å
837P89.7Confident93.7Very high118 Ų11855.2 Ų55.277%0.76631%0.305SS*.THydrogen-bonded Turntrans-54.4-39.9-180-2735.2000113.2C839P837-C839 VanDerWaalsContact C-N 3.31Å; P837-C839 PolarHBondContact O-N 3.03Å
838A82.9Confident94.1Very high24 Ų2452.2 Ų52.220%0.19829%0.292CS..THydrogen-bonded Turntrans-79.1-2.9179.200000114.8L681 Y703 P836 P840L681-A838 HydrophobicContact CD2-CB 3.87Å; Y703-A838 WeakPolarHBondContact CD2-O 3.45Å; Y703-A838 WeakPolarHBondContact CE2-O 3.4Å; P836-A838 PolarHBondContact O-N 2.97Å; A838-P840 WeakPolarHBondContact O-CD 3.41Å
839C92.2Very high94.4Very high1 Ų153.2 Ų53.21%0.00727%0.274CS..  trans-96.2117-172.2-174.60000112L800 R835 P836 P837L800-C839 HydrophobicContact CD1-CB 3.65Å; L800-C839 VanDerWaalsContact CD1-SG 3.59Å; R835-C839 WeakPolarHBondContact CD-O 3.37Å; R835-C839 HydrophobicContact CG-CB 4.04Å; R835-C839 PolarHBondContact NH1-O 3.12Å; P836-C839 HydrophobicContact CB-CB 3.88Å; P836-C839 HydrophobicContact CG-CB 4.08Å; P836-C839 WeakPolarHBondContact O-CB 3.5Å; P836-C839 PolarHBondContact O-N 2.85Å; P837-C839 VanDerWaalsContact C-N 3.31Å; P837-C839 PolarHBondContact O-N 3.03Å
840P91.7Very high94.7Very high55 Ų5547.3 Ų47.336%0.35725%0.252SS..  trans-63.9154.4172-21.534.4000112.5Y703 A838 G842 L843 Y844Y703-P840 HydrophobicContact CE1-CG 4.45Å; Y703-P840 WeakPolarHBondContact OH-CD 3.48Å; Y703-P840 WeakPolarHBondContact OH-CG 3.48Å; A838-P840 WeakPolarHBondContact O-CD 3.41Å; P840-G842 PolarHBondContact O-N 3.12Å; P840-L843 PolarHBondContact O-N 3.49Å; P840-L843 VanDerWaalsContact O-N 3.08Å; P840-Y844 PolarHBondContact O-N 2.64Å
841Q91.5Very high94.9Very high100 Ų10046.4 Ų46.447%0.46725%0.248SC..Hα-helixtrans-56.7-45.1-174.4-179.958.424.800113.5L843 Y844 E845Q841-L843 VanDerWaalsContact C-N 3.29Å; Q841-L843 PolarHBondContact O-N 3.41Å; Q841-Y844 WeakPolarHBondContact O-CB 3.3Å; Q841-Y844 PolarHBondContact O-N 3.25Å; Q841-Y844 VanDerWaalsContact O-N 3.15Å; Q841-E845 WeakPolarHBondContact CG-OE1 3.29Å; Q841-E845 PolarHBondContact NE2-OE1 2.89Å; Q841-E845 WeakPolarHBondContact O-CG 3.48Å; Q841-E845 PolarHBondContact O-N 3.38Å
842G91.3Very high95Very high35 Ų3544.6 Ų44.636%0.36124%0.238SC..Hα-helixtrans-65.9-27.9178.800000114.3P840 L846P840-G842 PolarHBondContact O-N 3.12Å; G842-L846 PolarHBondContact O-N 3.02Å
843L93.8Very high94.8Very high4 Ų443.9 Ų43.92%0.02124%0.235CC..Hα-helixtrans-77.3-33.1173.9-175.660.1000111.5Y703 L707 L796 L800 P840 Q841 L846 M847 F867 L868Y703-L843 VanDerWaalsContact OH-CD2 3.26Å; Y703-L843 WeakPolarHBondContact OH-CD2 3.23Å; L707-L843 HydrophobicContact CD2-CD2 3.8Å; L796-L843 HydrophobicContact CD2-CD1 4.05Å; L800-L843 HydrophobicContact CD1-CD2 3.63Å; L800-L843 HydrophobicContact CD1-CG 4.34Å; P840-L843 PolarHBondContact O-N 3.49Å; P840-L843 VanDerWaalsContact O-N 3.08Å; Q841-L843 VanDerWaalsContact C-N 3.29Å; Q841-L843 PolarHBondContact O-N 3.41Å; L843-L846 HydrophobicContact CD1-CD2 4.18Å; L843-L846 WeakPolarHBondContact O-CB 3.31Å; L843-L846 PolarHBondContact O-N 2.92Å; L843-M847 PolarHBondContact O-N 2.73Å; L843-M847 VanDerWaalsContact O-N 3.17Å; L843-F867 HydrophobicContact CB-CE1 4.37Å; L843-F867 HydrophobicContact CD1-CD1 4.1Å; L843-F867 HydrophobicContact CD1-CE1 3.84Å; L843-L868 HydrophobicContact CD1-CD2 3.74Å
844Y96.8Very high94.7Very high36 Ų3646.4 Ų46.414%0.14125%0.246CC..Hα-helixtrans-68.3-37.6171.5-176.4-117.8000112.3L833 R835 P840 Q841 L846 M847 L848L833-Y844 WeakPolarHBondContact O-CE2 3.27Å; L833-Y844 PolarHBondContact O-OH 2.81Å; L833-Y844 VanDerWaalsContact O-OH 3.14Å; R835-Y844 VanDerWaalsContact CA-CE2 3.47Å; R835-Y844 HydrophobicContact CB-CD1 3.92Å; R835-Y844 HydrophobicContact CB-CD2 3.66Å; R835-Y844 HydrophobicContact CB-CE1 4.01Å; R835-Y844 HydrophobicContact CB-CE2 3.77Å; R835-Y844 HydrophobicContact CB-CG 3.73Å; R835-Y844 HydrophobicContact CG-CD1 4.13Å; R835-Y844 HydrophobicContact CG-CD2 3.85Å; R835-Y844 HydrophobicContact CG-CE2 4.47Å; R835-Y844 HydrophobicContact CG-CG 3.65Å; P840-Y844 PolarHBondContact O-N 2.64Å; Q841-Y844 WeakPolarHBondContact O-CB 3.3Å; Q841-Y844 PolarHBondContact O-N 3.25Å; Q841-Y844 VanDerWaalsContact O-N 3.15Å; Y844-L846 VanDerWaalsContact C-N 3.25Å; Y844-L846 PolarHBondContact O-N 2.78Å; Y844-M847 HydrophobicContact CD2-SD 3.88Å; Y844-M847 WeakPolarHBondContact O-CA 3.42Å; Y844-M847 WeakPolarHBondContact O-CB 3.47Å; Y844-M847 PolarHBondContact O-N 3.21Å; Y844-M847 VanDerWaalsContact O-N 3.07Å; Y844-L848 HydrophobicContact CD1-CD1 4.08Å; Y844-L848 HydrophobicContact CD1-CG 4.45Å; Y844-L848 HydrophobicContact CE1-CD1 3.79Å; Y844-L848 HydrophobicContact CE1-CD2 4.35Å; Y844-L848 HydrophobicContact CE1-CG 4.15Å; Y844-L848 WeakPolarHBondContact O-CG 3.43Å; Y844-L848 PolarHBondContact O-N 3.25Å
845E96.4Very high94.6Very high97 Ų9743.5 Ų43.545%0.45323%0.226SC..Hα-helixtrans-63.2-31.6172.1-74166.4-166.200112.3Q841 L848 R849Q841-E845 WeakPolarHBondContact CG-OE1 3.29Å; Q841-E845 PolarHBondContact NE2-OE1 2.89Å; Q841-E845 WeakPolarHBondContact O-CG 3.48Å; Q841-E845 PolarHBondContact O-N 3.38Å; E845-L848 PolarHBondContact O-N 3.25Å; E845-R849 WeakPolarHBondContact O-CG 3.2Å; E845-R849 PolarHBondContact O-N 2.74Å
846L95.9Very high94.4Very high7 Ų745.3 Ų45.34%0.03724%0.239CC..Hα-helixtrans-66-40.5169.9-16869.8000112G842 L843 Y844 R849 C850 P859 L864 F867G842-L846 PolarHBondContact O-N 3.02Å; L843-L846 HydrophobicContact CD1-CD2 4.18Å; L843-L846 WeakPolarHBondContact O-CB 3.31Å; L843-L846 PolarHBondContact O-N 2.92Å; Y844-L846 VanDerWaalsContact C-N 3.25Å; Y844-L846 PolarHBondContact O-N 2.78Å; L846-R849 PolarHBondContact O-N 3.02Å; L846-C850 PolarHBondContact O-N 3.26Å; L846-C850 VanDerWaalsContact O-N 3.09Å; L846-C850 PolarHBondContact O-SG 3.25Å; L846-C850 VanDerWaalsContact O-SG 3.36Å; L846-P859 HydrophobicContact CD1-CG 4.37Å; L846-L864 HydrophobicContact CD1-CD2 3.98Å; L846-L864 HydrophobicContact CD2-CD2 3.79Å; L846-L864 HydrophobicContact CG-CD2 3.77Å; L846-F867 HydrophobicContact CD2-CB 4.01Å; L846-F867 HydrophobicContact CD2-CD1 3.55Å; L846-F867 HydrophobicContact CD2-CE1 4.16Å; L846-F867 HydrophobicContact CD2-CG 3.82Å
847M98Very high94.4Very high0 Ų050.6 Ų50.60%026%0.264CS..Hα-helixtrans-61-47172.6-63.5172.316600111.7L796 W797 L800 P836 L843 Y844 R849 C850 W851L796-M847 HydrophobicContact CB-CE 4.11Å; L796-M847 HydrophobicContact CD2-CE 3.86Å; L796-M847 HydrophobicContact CD2-CG 3.92Å; L796-M847 HydrophobicContact CG-CE 3.59Å; W797-M847 HydrophobicContact CB-CE 4.1Å; W797-M847 HydrophobicContact CB-SD 4.44Å; L800-M847 HydrophobicContact CD1-CE 3.7Å; P836-M847 HydrophobicContact CG-CE 4.49Å; L843-M847 PolarHBondContact O-N 2.73Å; L843-M847 VanDerWaalsContact O-N 3.17Å; Y844-M847 HydrophobicContact CD2-SD 3.88Å; Y844-M847 WeakPolarHBondContact O-CA 3.42Å; Y844-M847 WeakPolarHBondContact O-CB 3.47Å; Y844-M847 PolarHBondContact O-N 3.21Å; Y844-M847 VanDerWaalsContact O-N 3.07Å; M847-R849 PolarHBondContact O-N 2.75Å; M847-C850 WeakPolarHBondContact O-CA 3.46Å; M847-C850 VanDerWaalsContact O-CB 3.27Å; M847-C850 WeakPolarHBondContact O-CB 3.18Å; M847-C850 PolarHBondContact O-N 2.85Å; M847-W851 HydrophobicContact CB-CE3 4.29Å; M847-W851 HydrophobicContact CB-CH2 3.76Å; M847-W851 HydrophobicContact CB-CZ2 4.28Å; M847-W851 HydrophobicContact CB-CZ3 3.78Å; M847-W851 HydrophobicContact CG-CH2 4.39Å; M847-W851 PolarHBondContact O-N 2.85Å; M847-W851 HydrophobicContact SD-CH2 4.29Å
848L97.9Very high94.9Very high54 Ų5445.7 Ų45.728%0.28323%0.23SC..Hα-helixtrans-59.1-36.8177.8-67.4175.4000111.7Y832 Y844 E845 W851 S852Y832-L848 HydrophobicContact CD1-CD2 3.75Å; Y832-L848 HydrophobicContact CE1-CD2 4.32Å; Y832-L848 HydrophobicContact CG-CD2 3.92Å; Y844-L848 HydrophobicContact CD1-CD1 4.08Å; Y844-L848 HydrophobicContact CD1-CG 4.45Å; Y844-L848 HydrophobicContact CE1-CD1 3.79Å; Y844-L848 HydrophobicContact CE1-CD2 4.35Å; Y844-L848 HydrophobicContact CE1-CG 4.15Å; Y844-L848 WeakPolarHBondContact O-CG 3.43Å; Y844-L848 PolarHBondContact O-N 3.25Å; E845-L848 PolarHBondContact O-N 3.25Å; L848-W851 HydrophobicContact CD2-CE3 4.17Å; L848-W851 HydrophobicContact CD2-CZ3 4.41Å; L848-W851 CarbonylContact O-C 3.59Å; L848-W851 WeakPolarHBondContact O-CA 3.43Å; L848-W851 PolarHBondContact O-N 3.46Å; L848-W851 VanDerWaalsContact O-N 3.1Å; L848-S852 PolarHBondContact O-N 2.86Å
849R97.9Very high95.6Very high91 Ų9144.6 Ų44.634%0.34322%0.221SC..Hα-helixtrans-68.9-28.4171.8-74.5-17660.7-138.5-9.7114E845 L846 M847 W851 S852 R858 P859E845-R849 WeakPolarHBondContact O-CG 3.2Å; E845-R849 PolarHBondContact O-N 2.74Å; L846-R849 PolarHBondContact O-N 3.02Å; M847-R849 PolarHBondContact O-N 2.75Å; R849-W851 PolarHBondContact O-N 3.29Å; R849-S852 PolarHBondContact O-N 3.43Å; R849-S852 PolarHBondContact O-OG 2.87Å; R849-R858 WeakPolarHBondContact O-CA 3.42Å; R849-P859 HydrophobicContact CB-CG 4.44Å; R849-P859 VanDerWaalsContact O-CD 3.27Å; R849-P859 WeakPolarHBondContact O-CD 3.47Å
850C98.3Very high95.8Very high1 Ų147.9 Ų47.91%0.00724%0.243CC..Hα-helixtrans-66.1-26.3168.6-63.60000112V789 W790 L846 M847 R858V789-C850 HydrophobicContact CG1-CB 4.09Å; V789-C850 WeakPolarHBondContact O-CB 3.28Å; W790-C850 WeakPolarHBondContact CA-O 3.35Å; L846-C850 PolarHBondContact O-N 3.26Å; L846-C850 VanDerWaalsContact O-N 3.09Å; L846-C850 PolarHBondContact O-SG 3.25Å; L846-C850 VanDerWaalsContact O-SG 3.36Å; M847-C850 WeakPolarHBondContact O-CA 3.46Å; M847-C850 VanDerWaalsContact O-CB 3.27Å; M847-C850 WeakPolarHBondContact O-CB 3.18Å; M847-C850 PolarHBondContact O-N 2.85Å; C850-R858 WeakPolarHBondContact O-CD 3.27Å
851W98.4Very high96.1Very high6 Ų645.6 Ų45.62%0.02323%0.227CC..THydrogen-bonded Turntrans-101.321.2179.3-51-40.4000113.9W790 G793 V794 W797 Y832 L833 M847 L848 R849W790-W851 AromaticContact CD1-CD1 3.9Å; W790-W851 HydrophobicContact CD2-CB 4.45Å; W790-W851 AromaticContact CD2-CD1 3.61Å; W790-W851 HydrophobicContact CD2-CG 4.39Å; W790-W851 AromaticContact CE2-CD1 3.71Å; W790-W851 HydrophobicContact CE3-CB 4.21Å; W790-W851 AromaticContact CG-CD1 3.73Å; W790-W851 HydrophobicContact CH2-CB 4.2Å; W790-W851 HydrophobicContact CZ2-CB 4.44Å; W790-W851 HydrophobicContact CZ3-CB 4.08Å; W790-W851 WeakPolarHBondContact CZ3-O 3.32Å; W790-W851 AromaticContact NE1-CD1 3.87Å; W790-W851 PolarHBondContact O-NE1 3.33Å; G793-W851 VanDerWaalsContact C-CZ2 3.44Å; G793-W851 WeakPolarHBondContact O-CZ2 3.29Å; V794-W851 HydrophobicContact CG2-CZ2 4.19Å; W797-W851 HydrophobicContact CB-CH2 4.47Å; Y832-W851 HydrophobicContact CD1-CB 4.13Å; Y832-W851 HydrophobicContact CD1-CE3 4.02Å; Y832-W851 HydrophobicContact CE1-CB 4.07Å; L833-W851 HydrophobicContact CB-CH2 3.76Å; L833-W851 HydrophobicContact CB-CZ2 4.44Å; L833-W851 HydrophobicContact CB-CZ3 4.16Å; L833-W851 HydrophobicContact CD1-CH2 3.93Å; L833-W851 HydrophobicContact CD1-CZ2 3.79Å; L833-W851 HydrophobicContact CG-CH2 4.24Å; L833-W851 HydrophobicContact CG-CZ2 4.45Å; M847-W851 HydrophobicContact CB-CE3 4.29Å; M847-W851 HydrophobicContact CB-CH2 3.76Å; M847-W851 HydrophobicContact CB-CZ2 4.28Å; M847-W851 HydrophobicContact CB-CZ3 3.78Å; M847-W851 HydrophobicContact CG-CH2 4.39Å; M847-W851 PolarHBondContact O-N 2.85Å; M847-W851 HydrophobicContact SD-CH2 4.29Å; L848-W851 HydrophobicContact CD2-CE3 4.17Å; L848-W851 HydrophobicContact CD2-CZ3 4.41Å; L848-W851 CarbonylContact O-C 3.59Å; L848-W851 WeakPolarHBondContact O-CA 3.43Å; L848-W851 PolarHBondContact O-N 3.46Å; L848-W851 VanDerWaalsContact O-N 3.1Å; R849-W851 PolarHBondContact O-N 3.29Å
852S97.9Very high96.3Very high23 Ų2344 Ų4416%0.16123%0.227CC..  trans-58.4138.6168.4-730000111L848 R849 R858L848-S852 PolarHBondContact O-N 2.86Å; R849-S852 PolarHBondContact O-N 3.43Å; R849-S852 PolarHBondContact O-OG 2.87Å; S852-R858 PolarHBondContact O-NE 2.74Å; S852-R858 PolarHBondContact O-NH2 2.7Å
853R94.7Very high96.6Very high64 Ų6445.7 Ų45.724%0.24223%0.226CC..SBendtrans-55-59.5177.3-176.2-177.1-175.6-85.95110.8W775 F823 F824 R858W775-R853 HydrophobicContact CZ2-CG 4.35Å; W775-R853 PolarHBondContact NE1-O 3.34Å; F823-R853 WeakPolarHBondContact O-CD 3.25Å; F823-R853 WeakPolarHBondContact O-CG 3.37Å; F823-R853 PolarHBondContact O-NE 2.89Å; F823-R853 VanDerWaalsContact O-NE 3.15Å; F824-R853 PolarHBondContact O-NE 3.32Å; F824-R853 PolarHBondContact O-NH2 2.79Å; R853-R858 PolarHBondContact O-NH2 2.84Å
854E94.2Very high96.8Very high56 Ų5645.5 Ų45.526%0.26223%0.225SC..SBendtrans-69.9135.8178-48.5-37.8125.400111.3E856 Q857E854-E856 VanDerWaalsContact C-N 3.33Å; E854-E856 PolarHBondContact O-N 3.28Å; E854-Q857 HydrophobicContact CB-CG 4.05Å; E854-Q857 PolarHBondContact O-N 3.41Å
855S94.4Very high96.8Very high25 Ų2545.8 Ų45.818%0.17523%0.227CC..G310 helixtrans-67.3-34.2-173.7-58.20000112.7R858S855-R858 WeakPolarHBondContact O-CB 3.36Å; S855-R858 PolarHBondContact O-N 2.83Å
856E93.2Very high96.7Very high154 Ų15445.7 Ų45.772%0.7222%0.223SC*.G310 helixtrans-77.5-14.5-176.864-87.9-156.400114.4E854E854-E856 VanDerWaalsContact C-N 3.33Å; E854-E856 PolarHBondContact O-N 3.28Å
857Q96.2Very high96.6Very high112 Ų11247.6 Ų47.652%0.52323%0.231SC..G310 helixtrans-82.5-18.6174.6-65.2179.118.100112.4E854E854-Q857 HydrophobicContact CB-CG 4.05Å; E854-Q857 PolarHBondContact O-N 3.41Å
858R98.3Very high96.3Very high14 Ų1447.6 Ų47.65%0.05323%0.231CC..SBendtrans-70.7137.5-176.7-57.1178.1-166.5162.77.6110.5E776 A786 V789 R849 C850 S852 R853 S855E776-R858 IonicContact OE1-CZ 3.14Å; E776-R858 IonicContact OE1-NH1 3.29Å; E776-R858 PolarHBondContact OE1-NH1 3.04Å; E776-R858 IonicContact OE1-NH2 2.65Å; E776-R858 PolarHBondContact OE1-NH2 2.9Å; E776-R858 IonicContact OE2-CZ 2.7Å; E776-R858 IonicContact OE2-NH1 2.7Å; E776-R858 IonicContact OE2-NH2 3.87Å; E776-R858 PolarHBondContact OE2-NH2 2.73Å; A786-R858 VanDerWaalsContact O-CD 3.26Å; A786-R858 WeakPolarHBondContact O-CD 3.49Å; A786-R858 PolarHBondContact O-NH1 2.72Å; V789-R858 HydrophobicContact CG1-CB 3.86Å; R849-R858 WeakPolarHBondContact O-CA 3.42Å; C850-R858 WeakPolarHBondContact O-CD 3.27Å; S852-R858 PolarHBondContact O-NE 2.74Å; S852-R858 PolarHBondContact O-NH2 2.7Å; R853-R858 PolarHBondContact O-NH2 2.84Å; S855-R858 WeakPolarHBondContact O-CB 3.36Å; S855-R858 PolarHBondContact O-N 2.83Å
859P97.8Very high96Very high1 Ų147 Ų471%0.00623%0.233CC..PPolyproline II helixtrans-67.6134.8-175.127.7-34.9000111.5V789 L846 R849 Q863 L864V789-P859 HydrophobicContact CG1-CG 4.31Å; V789-P859 WeakPolarHBondContact CG1-O 3.36Å; V789-P859 WeakPolarHBondContact CG2-O 3.27Å; L846-P859 HydrophobicContact CD1-CG 4.37Å; R849-P859 HydrophobicContact CB-CG 4.44Å; R849-P859 VanDerWaalsContact O-CD 3.27Å; R849-P859 WeakPolarHBondContact O-CD 3.47Å; P859-Q863 HydrophobicContact CB-CB 4.4Å; P859-Q863 HydrophobicContact CB-CG 4.48Å; P859-L864 HydrophobicContact CB-CD2 4.17Å; P859-L864 HydrophobicContact CB-CG 4.19Å; P859-L864 HydrophobicContact CG-CD1 4.39Å; P859-L864 HydrophobicContact CG-CD2 3.66Å; P859-L864 HydrophobicContact CG-CG 4.03Å
860P97.3Very high95.3Very high71 Ų7147 Ų4746%0.46124%0.237SC..PPolyproline II helixtrans-67.2153.2174.229.1-35000110.9S862 Q863 L864P860-S862 PolarHBondContact O-N 3.45Å; P860-Q863 HydrophobicContact CG-CB 4.07Å; P860-Q863 WeakPolarHBondContact O-CA 3.36Å; P860-Q863 WeakPolarHBondContact O-CB 3.46Å; P860-Q863 PolarHBondContact O-N 2.68Å; P860-L864 PolarHBondContact O-N 2.85Å; P860-L864 VanDerWaalsContact O-N 3.1Å
861F98.2Very high94.2Very high6 Ų649.5 Ų49.53%0.02625%0.251CS..Hα-helixtrans-56-25.2179.3-75.1-67.6000114.6M717 R718 A721 T785 D788 V789 F792 L864 H865M717-F861 HydrophobicContact CB-CD1 3.51Å; M717-F861 HydrophobicContact CB-CD2 3.99Å; M717-F861 HydrophobicContact CB-CE1 3.37Å; M717-F861 HydrophobicContact CB-CE2 3.87Å; M717-F861 HydrophobicContact CB-CG 3.82Å; M717-F861 HydrophobicContact CB-CZ 3.57Å; M717-F861 HydrophobicContact CE-CE2 4.06Å; M717-F861 HydrophobicContact CE-CZ 3.87Å; M717-F861 HydrophobicContact CG-CD1 4.49Å; M717-F861 HydrophobicContact CG-CE1 3.94Å; M717-F861 HydrophobicContact CG-CZ 4.04Å; R718-F861 HydrophobicContact CB-CB 3.8Å; A721-F861 HydrophobicContact CB-CD2 4.19Å; T785-F861 HydrophobicContact CG2-CD2 4.12Å; T785-F861 HydrophobicContact CG2-CE2 4.05Å; D788-F861 HydrophobicContact CB-CE2 4.09Å; D788-F861 HydrophobicContact CB-CZ 4.07Å; V789-F861 HydrophobicContact CB-CZ 4.4Å; V789-F861 HydrophobicContact CG2-CD1 4.48Å; V789-F861 HydrophobicContact CG2-CD2 3.93Å; V789-F861 HydrophobicContact CG2-CE1 4.18Å; V789-F861 HydrophobicContact CG2-CE2 3.58Å; V789-F861 HydrophobicContact CG2-CG 4.36Å; V789-F861 HydrophobicContact CG2-CZ 3.72Å; F792-F861 HydrophobicContact CB-CE1 3.64Å; F792-F861 HydrophobicContact CB-CZ 4.13Å; F792-F861 HydrophobicContact CD1-CE1 4.46Å; F792-F861 HydrophobicContact CD2-CE1 4.01Å; F792-F861 AromaticContact CG-CE1 3.77Å; F792-F861 HydrophobicContact CG-CE1 3.77Å; F861-L864 HydrophobicContact CD1-CD1 3.75Å; F861-L864 HydrophobicContact CE1-CD1 4.06Å; F861-L864 HydrophobicContact CG-CD1 4.47Å; F861-H865 VanDerWaalsContact O-CB 3.29Å; F861-H865 WeakPolarHBondContact O-CB 3.34Å; F861-H865 PolarHBondContact O-N 3.13Å
862S96Very high93Very high68 Ų6849.4 Ų49.448%0.47625%0.251SS..Hα-helixtrans-64.7-40.5169.950.20000113.3P860 R866P860-S862 PolarHBondContact O-N 3.45Å; S862-R866 WeakPolarHBondContact O-CB 3.3Å; S862-R866 PolarHBondContact O-N 3.33Å
863Q96.6Very high91.9Very high70 Ų7052.2 Ų52.233%0.32726%0.264SS..Hα-helixtrans-69.7-42.8174-175.217529.200110.9P859 P860 R866 F867P859-Q863 HydrophobicContact CB-CB 4.4Å; P859-Q863 HydrophobicContact CB-CG 4.48Å; P860-Q863 HydrophobicContact CG-CB 4.07Å; P860-Q863 WeakPolarHBondContact O-CA 3.36Å; P860-Q863 WeakPolarHBondContact O-CB 3.46Å; P860-Q863 PolarHBondContact O-N 2.68Å; Q863-R866 PolarHBondContact O-N 3.3Å; Q863-F867 PolarHBondContact O-N 2.84Å
864L97.6Very high90.7Very high0 Ų055.6 Ų55.60%029%0.287CS..Hα-helixtrans-60.1-51.2178.6-68.6170.4000112A714 V789 F792 L846 P859 P860 F861 R866 F867 L868A714-L864 HydrophobicContact CB-CB 4.41Å; V789-L864 HydrophobicContact CG1-CD1 4.19Å; V789-L864 HydrophobicContact CG2-CD1 4.28Å; F792-L864 HydrophobicContact CD1-CD1 3.69Å; F792-L864 HydrophobicContact CD1-CD2 4.36Å; F792-L864 HydrophobicContact CD1-CG 4.48Å; F792-L864 HydrophobicContact CE1-CB 4.25Å; F792-L864 HydrophobicContact CE1-CD1 4.04Å; F792-L864 HydrophobicContact CE1-CD2 4.16Å; F792-L864 HydrophobicContact CE1-CG 4.39Å; F792-L864 HydrophobicContact CG-CD1 4.4Å; L846-L864 HydrophobicContact CD1-CD2 3.98Å; L846-L864 HydrophobicContact CD2-CD2 3.79Å; L846-L864 HydrophobicContact CG-CD2 3.77Å; P859-L864 HydrophobicContact CB-CD2 4.17Å; P859-L864 HydrophobicContact CB-CG 4.19Å; P859-L864 HydrophobicContact CG-CD1 4.39Å; P859-L864 HydrophobicContact CG-CD2 3.66Å; P859-L864 HydrophobicContact CG-CG 4.03Å; P860-L864 PolarHBondContact O-N 2.85Å; P860-L864 VanDerWaalsContact O-N 3.1Å; F861-L864 HydrophobicContact CD1-CD1 3.75Å; F861-L864 HydrophobicContact CE1-CD1 4.06Å; F861-L864 HydrophobicContact CG-CD1 4.47Å; L864-R866 VanDerWaalsContact C-N 3.34Å; L864-R866 PolarHBondContact O-N 3.48Å; L864-F867 PolarHBondContact O-N 2.79Å; L864-L868 WeakPolarHBondContact O-CD1 3.45Å; L864-L868 WeakPolarHBondContact O-CG 3.43Å; L864-L868 PolarHBondContact O-N 2.94Å; L864-L868 VanDerWaalsContact O-N 3.07Å
865H97.1Very high89.1Confident42 Ų4258 Ų5819%0.19431%0.305CS..Hα-helixtrans-56.6-47.8175.5173.8-69.8000111.6A714 R718 F861 F867 L868 A869A714-H865 HydrophobicContact CB-CB 3.93Å; R718-H865 PolarHBondContact NH1-CD2 2.86Å; R718-H865 VanDerWaalsContact NH1-CD2 3.27Å; R718-H865 PolarHBondContact NH1-CE1 3.46Å; R718-H865 VanDerWaalsContact NH1-CG 3.28Å; R718-H865 PolarHBondContact NH1-ND1 3.02Å; R718-H865 PolarHBondContact NH1-NE2 2.98Å; R718-H865 PolarHBondContact NH2-CD2 2.65Å; R718-H865 PolarHBondContact NH2-NE2 2.58Å; F861-H865 VanDerWaalsContact O-CB 3.29Å; F861-H865 WeakPolarHBondContact O-CB 3.34Å; F861-H865 PolarHBondContact O-N 3.13Å; H865-F867 PolarHBondContact O-N 3.15Å; H865-L868 PolarHBondContact O-N 2.83Å; H865-A869 VanDerWaalsContact O-CB 3.29Å; H865-A869 WeakPolarHBondContact O-CB 3.39Å; H865-A869 PolarHBondContact O-N 2.93Å
866R94.1Very high87.5Confident94 Ų9461.6 Ų61.636%0.35533%0.326SS..Hα-helixtrans-62.6-44.5-177.3-160-167.76363.811.6111.3S862 Q863 L864 L868 A869 E870 D871S862-R866 WeakPolarHBondContact O-CB 3.3Å; S862-R866 PolarHBondContact O-N 3.33Å; Q863-R866 PolarHBondContact O-N 3.3Å; L864-R866 VanDerWaalsContact C-N 3.34Å; L864-R866 PolarHBondContact O-N 3.48Å; R866-L868 PolarHBondContact O-N 3.18Å; R866-A869 PolarHBondContact O-N 2.92Å; R866-E870 WeakPolarHBondContact CD-OE2 3.33Å; R866-E870 HydrophobicContact CG-CG 4.36Å; R866-E870 VanDerWaalsContact CG-OE1 3.32Å; R866-E870 WeakPolarHBondContact CG-OE1 3.25Å; R866-E870 WeakPolarHBondContact CG-OE2 3.44Å; R866-E870 IonicContact CZ-OE2 3.03Å; R866-E870 IonicContact NH1-OE2 3.05Å; R866-E870 PolarHBondContact NH1-OE2 3.04Å; R866-E870 WeakPolarHBondContact O-CB 3.42Å; R866-E870 PolarHBondContact O-N 3.33Å; R866-D871 IonicContact CZ-OD1 3.63Å; R866-D871 IonicContact CZ-OD2 3.09Å; R866-D871 VanDerWaalsContact NH1-CG 3.34Å; R866-D871 IonicContact NH1-OD1 3.51Å; R866-D871 PolarHBondContact NH1-OD1 3.16Å; R866-D871 IonicContact NH1-OD2 2.8Å; R866-D871 PolarHBondContact NH1-OD2 3.23Å; R866-D871 IonicContact NH2-OD1 3.37Å; R866-D871 IonicContact NH2-OD2 2.81Å; R866-D871 PolarHBondContact NH2-OD2 2.93Å
867F93.8Very high87.2Confident47 Ų4757 Ų5721%0.20631%0.306CS..Iπ-helixtrans-61.7-42.5177.1-170.2-83.9000112.2L843 L846 Q863 L864 H865 D871 A872L843-F867 HydrophobicContact CB-CE1 4.37Å; L843-F867 HydrophobicContact CD1-CD1 4.1Å; L843-F867 HydrophobicContact CD1-CE1 3.84Å; L846-F867 HydrophobicContact CD2-CB 4.01Å; L846-F867 HydrophobicContact CD2-CD1 3.55Å; L846-F867 HydrophobicContact CD2-CE1 4.16Å; L846-F867 HydrophobicContact CD2-CG 3.82Å; Q863-F867 PolarHBondContact O-N 2.84Å; L864-F867 PolarHBondContact O-N 2.79Å; H865-F867 PolarHBondContact O-N 3.15Å; F867-D871 HydrophobicContact CD2-CB 3.64Å; F867-D871 WeakPolarHBondContact CD2-OD2 3.45Å; F867-D871 HydrophobicContact CE2-CB 3.95Å; F867-D871 HydrophobicContact CG-CB 4.03Å; F867-D871 PolarHBondContact O-N 3.15Å; F867-A872 HydrophobicContact CD1-CB 4.08Å; F867-A872 HydrophobicContact CE1-CB 3.97Å; F867-A872 VanDerWaalsContact O-CB 3.3Å; F867-A872 WeakPolarHBondContact O-CB 3.49Å; F867-A872 PolarHBondContact O-N 2.84Å
868L93.5Very high86.7Confident1 Ų154.1 Ų54.11%0.00530%0.295CS..Iπ-helixtrans-72.5-33.4-178.6-69.3164.2000113.4L707 A710 A711 A714 F792 L796 L843 L864 H865 R866L707-L868 HydrophobicContact CD2-CD2 3.84Å; A710-L868 HydrophobicContact CB-CD1 4.02Å; A710-L868 HydrophobicContact CB-CD2 4.16Å; A711-L868 HydrophobicContact CB-CB 3.92Å; A714-L868 HydrophobicContact CB-CD1 4.24Å; F792-L868 HydrophobicContact CE1-CD1 4.11Å; F792-L868 HydrophobicContact CZ-CD1 3.63Å; L796-L868 HydrophobicContact CD1-CD2 4.01Å; L843-L868 HydrophobicContact CD1-CD2 3.74Å; L864-L868 WeakPolarHBondContact O-CD1 3.45Å; L864-L868 WeakPolarHBondContact O-CG 3.43Å; L864-L868 PolarHBondContact O-N 2.94Å; L864-L868 VanDerWaalsContact O-N 3.07Å; H865-L868 PolarHBondContact O-N 2.83Å; R866-L868 PolarHBondContact O-N 3.18Å
869A89.9Confident86.1Confident41 Ų4156.3 Ų56.334%0.33931%0.308SS..Iπ-helixtrans-86.7-28.1-178.900000114A711 H865 R866A711-A869 HydrophobicContact CB-CB 4.44Å; H865-A869 VanDerWaalsContact O-CB 3.29Å; H865-A869 WeakPolarHBondContact O-CB 3.39Å; H865-A869 PolarHBondContact O-N 2.93Å; R866-A869 PolarHBondContact O-N 2.92Å
870E84.4Confident85.4Confident91 Ų9159.5 Ų59.543%0.42533%0.326SS..Iπ-helixtrans-116.8-73.5-176.4-60.3163.6-161.300111R866 A872 L873 N874R866-E870 WeakPolarHBondContact CD-OE2 3.33Å; R866-E870 HydrophobicContact CG-CG 4.36Å; R866-E870 VanDerWaalsContact CG-OE1 3.32Å; R866-E870 WeakPolarHBondContact CG-OE1 3.25Å; R866-E870 WeakPolarHBondContact CG-OE2 3.44Å; R866-E870 IonicContact CZ-OE2 3.03Å; R866-E870 IonicContact NH1-OE2 3.05Å; R866-E870 PolarHBondContact NH1-OE2 3.04Å; R866-E870 WeakPolarHBondContact O-CB 3.42Å; R866-E870 PolarHBondContact O-N 3.33Å; E870-A872 PolarHBondContact O-N 3.39Å; E870-L873 PolarHBondContact O-N 3.27Å; E870-N874 PolarHBondContact O-N 2.98Å; E870-N874 VanDerWaalsContact O-N 3.08Å; E870-N874 PolarHBondContact O-ND2 2.73Å
871D74.4Confident84.7Confident54 Ų5458.8 Ų58.829%0.28932%0.318SS..Iπ-helixtrans-60-44.7-165.2-57.4-23.7000112.5R866 F867 T875R866-D871 IonicContact CZ-OD1 3.63Å; R866-D871 IonicContact CZ-OD2 3.09Å; R866-D871 VanDerWaalsContact NH1-CG 3.34Å; R866-D871 IonicContact NH1-OD1 3.51Å; R866-D871 PolarHBondContact NH1-OD1 3.16Å; R866-D871 IonicContact NH1-OD2 2.8Å; R866-D871 PolarHBondContact NH1-OD2 3.23Å; R866-D871 IonicContact NH2-OD1 3.37Å; R866-D871 IonicContact NH2-OD2 2.81Å; R866-D871 PolarHBondContact NH2-OD2 2.93Å; F867-D871 HydrophobicContact CD2-CB 3.64Å; F867-D871 WeakPolarHBondContact CD2-OD2 3.45Å; F867-D871 HydrophobicContact CE2-CB 3.95Å; F867-D871 HydrophobicContact CG-CB 4.03Å; F867-D871 PolarHBondContact O-N 3.15Å; D871-T875 WeakPolarHBondContact O-CG2 3.44Å
872A74Confident83.8Confident3 Ų362.3 Ų62.33%0.02534%0.337CS..THydrogen-bonded Turntrans-70.6-41.7179.600000112.1L707 F867 E870 N874 T875 V876L707-A872 HydrophobicContact CD1-CB 3.87Å; L707-A872 HydrophobicContact CD2-CB 4.1Å; F867-A872 HydrophobicContact CD1-CB 4.08Å; F867-A872 HydrophobicContact CE1-CB 3.97Å; F867-A872 VanDerWaalsContact O-CB 3.3Å; F867-A872 WeakPolarHBondContact O-CB 3.49Å; F867-A872 PolarHBondContact O-N 2.84Å; E870-A872 PolarHBondContact O-N 3.39Å; A872-N874 VanDerWaalsContact C-N 3.28Å; A872-N874 PolarHBondContact O-N 3.04Å; A872-T875 PolarHBondContact O-N 2.94Å; A872-T875 PolarHBondContact O-OG1 3.46Å; A872-V876 WeakPolarHBondContact O-CG2 3.48Å
873L73.8Confident82.9Confident82 Ų8261.9 Ų61.943%0.42933%0.327SS..G310 helixtrans-67.6-30.9-176.7-153.774.8000111.9P704 L707 E870 T875P704-L873 HydrophobicContact CB-CD1 4.07Å; L707-L873 HydrophobicContact CB-CD1 4.44Å; L707-L873 HydrophobicContact CD1-CD1 4.06Å; E870-L873 PolarHBondContact O-N 3.27Å; L873-T875 PolarHBondContact O-N 2.72Å
874N70.1Confident81.8Confident136 Ų13661.3 Ų61.373%0.72733%0.327SS*.G310 helixtrans-73.73.6172.6-68.8-44000114.2E870 A872E870-N874 PolarHBondContact O-N 2.98Å; E870-N874 VanDerWaalsContact O-N 3.08Å; E870-N874 PolarHBondContact O-ND2 2.73Å; A872-N874 VanDerWaalsContact C-N 3.28Å; A872-N874 PolarHBondContact O-N 3.04Å
875T61.4Low80.5Confident105 Ų10566.4 Ų66.464%0.64435%0.354SS*.G310 helixtrans-121.820.3-179.761.30000114D871 A872 L873D871-T875 WeakPolarHBondContact O-CG2 3.44Å; A872-T875 PolarHBondContact O-N 2.94Å; A872-T875 PolarHBondContact O-OG1 3.46Å; L873-T875 PolarHBondContact O-N 2.72Å
876V59.8Low79Confident101 Ų10168.6 Ų68.661%0.61237%0.369SS*.  trans-114.50-178.5-170.10000112.1Y703 P704 L707 A872Y703-V876 HydrophobicContact CD1-CG1 3.97Å; Y703-V876 HydrophobicContact CD1-CG2 3.75Å; Y703-V876 HydrophobicContact CE1-CG2 3.56Å; P704-V876 HydrophobicContact CG-CG1 4.03Å; L707-V876 HydrophobicContact CD1-CG2 4.25Å; A872-V876 WeakPolarHBondContact O-CG2 3.48Å

Retrieved 876 of 876 residues in 1422.4 ms (Link to these results)