A0A024RCX7_HUMAN Loading...

Zinc transporter SLC39A7

AlphaFold DB (Q92504), UniProt , Accession A0A024RCX7, Species HUMAN (Homo sapiens, Human), Gene n/a, Length 469 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	40.6	Very low	45.7	Very low	253 Å²	253	116.2 Å²	116.2	100%	1.246	66%	0.66	S	S	*	*				0	49.2	0	-66.3	172.9	172.4	0	0	111.3
2	A	44.6	Very low	46.2	Very low	76 Å²	76	110.8 Å²	110.8	63%	0.628	64%	0.641	S	S	*	*			trans	-130.8	19.4	-173.8	0	0	0	0	0	114	G4	A2-G4 PolarHBondContact O-N 3.18Å
3	R	42	Very low	47	Very low	261 Å²	261	107.2 Å²	107.2	99%	0.985	62%	0.621	S	S	*	*	T	Hydrogen-bonded Turn	trans	-86.1	99.3	170.8	-71.5	-177.5	176.6	172	-2.3	108.5
4	G	48.6	Very low	47.3	Very low	79 Å²	79	101.9 Å²	101.9	81%	0.814	60%	0.601	S	S	*	*	T	Hydrogen-bonded Turn	trans	157.3	-11.9	176	0	0	0	0	0	117.4	A2 G6	A2-G4 PolarHBondContact O-N 3.18Å; G4-G6 PolarHBondContact O-N 3.46Å
5	L	42.4	Very low	47.8	Very low	95 Å²	95	102.7 Å²	102.7	50%	0.497	60%	0.601	S	S	.	*			trans	-87.6	106.3	176.2	-75.3	160.2	0	0	0	110	H9 W10	L5-H9 HydrophobicContact CB-CB 4.42Å; L5-H9 HydrophobicContact CD2-CB 4.18Å; L5-W10 PolarHBondContact O-NE1 3.33Å
6	G	43.6	Very low	48.5	Very low	42 Å²	42	103.3 Å²	103.3	43%	0.433	60%	0.6	S	S	.	*			trans	-67.1	157.4	179.8	0	0	0	0	0	113.6	G4 P8 H9	G4-G6 PolarHBondContact O-N 3.46Å; G6-P8 WeakPolarHBondContact O-CD 3.41Å; G6-H9 PolarHBondContact O-N 2.82Å
7	A	46.7	Very low	49.3	Very low	76 Å²	76	101.5 Å²	101.5	63%	0.628	59%	0.591	S	S	*	*	T	Hydrogen-bonded Turn	trans	-35.8	-46.2	-175.7	0	0	0	0	0	117.9	H9 W10 V11	A7-H9 PolarHBondContact O-N 3.12Å; A7-H9 VanDerWaalsContact O-N 3.13Å; A7-W10 PolarHBondContact O-N 2.93Å; A7-W10 VanDerWaalsContact O-N 3.08Å; A7-V11 PolarHBondContact O-N 3.34Å
8	P	53.2	Low	49.8	Very low	98 Å²	98	101.2 Å²	101.2	64%	0.636	58%	0.578	S	S	*	*	H	α-helix	trans	-60.2	-25.5	-179.9	22.6	-35.3	0	0	0	114.3	G6 A12	G6-P8 WeakPolarHBondContact O-CD 3.41Å; P8-A12 WeakPolarHBondContact O-CB 3.14Å; P8-A12 PolarHBondContact O-N 3.47Å; P8-A12 VanDerWaalsContact O-N 3.08Å
9	H	46	Very low	50.3	Low	109 Å²	109	98.6 Å²	98.6	51%	0.505	57%	0.571	S	S	.	*	H	α-helix	trans	-70	-30.7	176.6	-85.5	-78.3	0	0	0	113.1	L5 G6 A7 A12 V13	L5-H9 HydrophobicContact CB-CB 4.42Å; L5-H9 HydrophobicContact CD2-CB 4.18Å; G6-H9 PolarHBondContact O-N 2.82Å; A7-H9 PolarHBondContact O-N 3.12Å; A7-H9 VanDerWaalsContact O-N 3.13Å; H9-A12 PolarHBondContact O-N 2.99Å; H9-V13 VanDerWaalsContact O-CG2 3.29Å; H9-V13 WeakPolarHBondContact O-CG2 3.42Å; H9-V13 PolarHBondContact O-N 3.28Å
10	W	47.9	Very low	50.9	Low	113 Å²	113	97.8 Å²	97.8	43%	0.428	57%	0.567	S	S	.	*	H	α-helix	trans	-78.5	-37.2	-179.5	-67	108.5	0	0	0	112.4	L5 A7 A12 V13 G14	L5-W10 PolarHBondContact O-NE1 3.33Å; A7-W10 PolarHBondContact O-N 2.93Å; A7-W10 VanDerWaalsContact O-N 3.08Å; W10-A12 VanDerWaalsContact C-N 3.29Å; W10-A12 PolarHBondContact O-N 3.46Å; W10-V13 HydrophobicContact CE3-CB 4.35Å; W10-V13 HydrophobicContact CE3-CG1 4.42Å; W10-V13 PolarHBondContact O-N 2.78Å; W10-V13 VanDerWaalsContact O-N 3.14Å; W10-G14 PolarHBondContact O-N 3.22Å
11	V	47.5	Very low	51.3	Low	76 Å²	76	95.9 Å²	95.9	46%	0.461	56%	0.555	S	S	.	*	H	α-helix	trans	-60.6	-42.2	167.8	-179.1	0	0	0	0	110.1	A7 V13 G14 L15	A7-V11 PolarHBondContact O-N 3.34Å; V11-V13 VanDerWaalsContact C-N 3.35Å; V11-V13 PolarHBondContact O-N 3.31Å; V11-G14 PolarHBondContact O-N 3.34Å; V11-L15 HydrophobicContact CG1-CD1 3.97Å; V11-L15 HydrophobicContact CG1-CG 4.43Å; V11-L15 WeakPolarHBondContact O-CB 3.44Å; V11-L15 VanDerWaalsContact O-CG 3.32Å; V11-L15 WeakPolarHBondContact O-CG 3.48Å; V11-L15 PolarHBondContact O-N 3.38Å
12	A	51.4	Low	52.1	Low	52 Å²	52	85.8 Å²	85.8	43%	0.43	52%	0.516	S	S	.	.	H	α-helix	trans	-63.2	-37.7	173.3	0	0	0	0	0	112.6	P8 H9 W10 L16	P8-A12 WeakPolarHBondContact O-CB 3.14Å; P8-A12 PolarHBondContact O-N 3.47Å; P8-A12 VanDerWaalsContact O-N 3.08Å; H9-A12 PolarHBondContact O-N 2.99Å; W10-A12 VanDerWaalsContact C-N 3.29Å; W10-A12 PolarHBondContact O-N 3.46Å; A12-L16 WeakPolarHBondContact O-CB 3.33Å; A12-L16 PolarHBondContact O-N 3.09Å
13	V	56.4	Low	52.8	Low	63 Å²	63	88.7 Å²	88.7	38%	0.382	52%	0.52	S	S	.	.	H	α-helix	trans	-66.2	-44.5	174.5	166.8	0	0	0	0	111.5	H9 W10 V11 L16 T17	H9-V13 VanDerWaalsContact O-CG2 3.29Å; H9-V13 WeakPolarHBondContact O-CG2 3.42Å; H9-V13 PolarHBondContact O-N 3.28Å; W10-V13 HydrophobicContact CE3-CB 4.35Å; W10-V13 HydrophobicContact CE3-CG1 4.42Å; W10-V13 PolarHBondContact O-N 2.78Å; W10-V13 VanDerWaalsContact O-N 3.14Å; V11-V13 VanDerWaalsContact C-N 3.35Å; V11-V13 PolarHBondContact O-N 3.31Å; V13-L16 CarbonylContact O-C 3.58Å; V13-L16 PolarHBondContact O-N 3.14Å; V13-T17 WeakPolarHBondContact O-CG2 3.26Å; V13-T17 PolarHBondContact O-N 2.92Å; V13-T17 PolarHBondContact O-OG1 2.86Å
14	G	51.8	Low	53.5	Low	33 Å²	33	80 Å²	80	34%	0.34	49%	0.493	S	S	.	.	H	α-helix	trans	-64.3	-41.2	177	0	0	0	0	0	113.2	W10 V11 L16 T17 W18	W10-G14 PolarHBondContact O-N 3.22Å; V11-G14 PolarHBondContact O-N 3.34Å; G14-L16 VanDerWaalsContact C-N 3.34Å; G14-T17 WeakPolarHBondContact CA-OG1 3.38Å; G14-T17 PolarHBondContact O-OG1 3.31Å; G14-W18 WeakPolarHBondContact O-CB 3.31Å; G14-W18 PolarHBondContact O-N 2.94Å; G14-W18 VanDerWaalsContact O-N 3.09Å
15	L	54.4	Low	53.8	Low	115 Å²	115	77.8 Å²	77.8	60%	0.602	46%	0.463	S	S	*	.	H	α-helix	trans	-69.2	-32	172.5	-69.3	173.7	0	0	0	112.2	V11 W18 A19	V11-L15 HydrophobicContact CG1-CD1 3.97Å; V11-L15 HydrophobicContact CG1-CG 4.43Å; V11-L15 WeakPolarHBondContact O-CB 3.44Å; V11-L15 VanDerWaalsContact O-CG 3.32Å; V11-L15 WeakPolarHBondContact O-CG 3.48Å; V11-L15 PolarHBondContact O-N 3.38Å; L15-W18 WeakPolarHBondContact O-CB 3.42Å; L15-A19 WeakPolarHBondContact O-CB 3.46Å; L15-A19 PolarHBondContact O-N 3.09Å
16	L	59.1	Low	54.3	Low	111 Å²	111	75.4 Å²	75.4	58%	0.581	46%	0.457	S	S	*	.	H	α-helix	trans	-73.9	-40.6	176.5	-171.6	71.8	0	0	0	111.4	A12 V13 G14 W18 A19 T20	A12-L16 WeakPolarHBondContact O-CB 3.33Å; A12-L16 PolarHBondContact O-N 3.09Å; V13-L16 CarbonylContact O-C 3.58Å; V13-L16 PolarHBondContact O-N 3.14Å; G14-L16 VanDerWaalsContact C-N 3.34Å; L16-W18 VanDerWaalsContact C-N 3.29Å; L16-W18 PolarHBondContact O-N 2.94Å; L16-A19 PolarHBondContact O-N 3.14Å; L16-T20 WeakPolarHBondContact O-CG2 3.37Å; L16-T20 PolarHBondContact O-N 3.14Å; L16-T20 PolarHBondContact O-OG1 2.81Å; L16-T20 VanDerWaalsContact O-OG1 3.14Å
17	T	61.1	Low	54.4	Low	73 Å²	73	75.8 Å²	75.8	45%	0.448	46%	0.461	S	S	.	.	H	α-helix	trans	-60.6	-43.3	172.3	49.4	0	0	0	0	110	V13 G14 T20 L21	V13-T17 WeakPolarHBondContact O-CG2 3.26Å; V13-T17 PolarHBondContact O-N 2.92Å; V13-T17 PolarHBondContact O-OG1 2.86Å; G14-T17 WeakPolarHBondContact CA-OG1 3.38Å; G14-T17 PolarHBondContact O-OG1 3.31Å; T17-T20 WeakPolarHBondContact CA-OG1 3.23Å; T17-T20 PolarHBondContact O-N 2.95Å; T17-T20 PolarHBondContact O-OG1 3.37Å; T17-L21 WeakPolarHBondContact O-CB 3.3Å; T17-L21 PolarHBondContact O-N 3.43Å
18	W	59.4	Low	54.7	Low	96 Å²	96	77.1 Å²	77.1	36%	0.364	46%	0.457	S	S	.	.	H	α-helix	trans	-55.7	-50.3	169.5	-106.2	88.2	0	0	0	113.7	G14 L15 L16 T20 L21 G22 L172 V364	G14-W18 WeakPolarHBondContact O-CB 3.31Å; G14-W18 PolarHBondContact O-N 2.94Å; G14-W18 VanDerWaalsContact O-N 3.09Å; L15-W18 WeakPolarHBondContact O-CB 3.42Å; L16-W18 VanDerWaalsContact C-N 3.29Å; L16-W18 PolarHBondContact O-N 2.94Å; W18-T20 VanDerWaalsContact C-N 3.32Å; W18-T20 PolarHBondContact O-N 2.65Å; W18-L21 PolarHBondContact O-N 3.29Å; W18-G22 PolarHBondContact O-N 2.79Å; W18-L172 HydrophobicContact CH2-CD2 4.42Å; W18-V364 HydrophobicContact CH2-CG1 3.75Å; W18-V364 HydrophobicContact CH2-CG2 4.18Å; W18-V364 HydrophobicContact CZ2-CB 4.42Å; W18-V364 HydrophobicContact CZ2-CG1 3.89Å; W18-V364 HydrophobicContact CZ2-CG2 4.18Å
19	A	59.4	Low	54.4	Low	53 Å²	53	75.2 Å²	75.2	44%	0.438	46%	0.455	S	S	.	.	H	α-helix	trans	-62.3	-39.3	178.2	0	0	0	0	0	111.7	L15 L16 L23	L15-A19 WeakPolarHBondContact O-CB 3.46Å; L15-A19 PolarHBondContact O-N 3.09Å; L16-A19 PolarHBondContact O-N 3.14Å; A19-L23 WeakPolarHBondContact O-CB 3.39Å; A19-L23 PolarHBondContact O-N 2.82Å
20	T	61.3	Low	54.2	Low	81 Å²	81	72.8 Å²	72.8	50%	0.497	46%	0.46	S	S	.	.	H	α-helix	trans	-70.2	-39.3	176.9	57.7	0	0	0	0	112.6	L16 T17 W18 L23 L24	L16-T20 WeakPolarHBondContact O-CG2 3.37Å; L16-T20 PolarHBondContact O-N 3.14Å; L16-T20 PolarHBondContact O-OG1 2.81Å; L16-T20 VanDerWaalsContact O-OG1 3.14Å; T17-T20 WeakPolarHBondContact CA-OG1 3.23Å; T17-T20 PolarHBondContact O-N 2.95Å; T17-T20 PolarHBondContact O-OG1 3.37Å; W18-T20 VanDerWaalsContact C-N 3.32Å; W18-T20 PolarHBondContact O-N 2.65Å; T20-L23 PolarHBondContact O-N 3.35Å; T20-L24 VanDerWaalsContact O-CB 3.23Å; T20-L24 WeakPolarHBondContact O-CB 3.35Å; T20-L24 PolarHBondContact O-N 2.85Å
21	L	60.8	Low	54.2	Low	59 Å²	59	75.5 Å²	75.5	31%	0.309	48%	0.477	S	S	.	.	H	α-helix	trans	-65.4	-44.5	174.5	-173	66.2	0	0	0	110.4	T17 W18 L23 L24 V25	T17-L21 WeakPolarHBondContact O-CB 3.3Å; T17-L21 PolarHBondContact O-N 3.43Å; W18-L21 PolarHBondContact O-N 3.29Å; L21-L23 PolarHBondContact O-N 3.27Å; L21-L24 PolarHBondContact O-N 2.95Å; L21-V25 WeakPolarHBondContact O-CB 3.33Å; L21-V25 VanDerWaalsContact O-CG2 3.3Å; L21-V25 WeakPolarHBondContact O-CG2 3.49Å; L21-V25 PolarHBondContact O-N 3.08Å
22	G	55.7	Low	54.2	Low	41 Å²	41	78.2 Å²	78.2	42%	0.423	49%	0.489	S	S	.	.	H	α-helix	trans	-59.4	-42.2	173.3	0	0	0	0	0	113.1	W18 A26	W18-G22 PolarHBondContact O-N 2.79Å; G22-A26 WeakPolarHBondContact O-CB 3.37Å; G22-A26 PolarHBondContact O-N 2.85Å
23	L	59.1	Low	54	Low	136 Å²	136	83 Å²	83	71%	0.712	51%	0.507	S	S	*	.	H	α-helix	trans	-69.5	-38.5	175	-121.2	79.9	0	0	0	112.7	A19 T20 L21 A26 G27	A19-L23 WeakPolarHBondContact O-CB 3.39Å; A19-L23 PolarHBondContact O-N 2.82Å; T20-L23 PolarHBondContact O-N 3.35Å; L21-L23 PolarHBondContact O-N 3.27Å; L23-A26 PolarHBondContact O-N 3.46Å; L23-G27 WeakPolarHBondContact O-CA 3.37Å; L23-G27 PolarHBondContact O-N 3.22Å
24	L	57.9	Low	53.3	Low	80 Å²	80	87.5 Å²	87.5	42%	0.419	53%	0.528	S	S	.	.	H	α-helix	trans	-63.6	-48.5	179.1	-167.5	83.1	0	0	0	110.2	T20 L21 A26 G27 L28 L450	T20-L24 VanDerWaalsContact O-CB 3.23Å; T20-L24 WeakPolarHBondContact O-CB 3.35Å; T20-L24 PolarHBondContact O-N 2.85Å; L21-L24 PolarHBondContact O-N 2.95Å; L24-A26 VanDerWaalsContact C-N 3.32Å; L24-A26 PolarHBondContact O-N 2.88Å; L24-G27 PolarHBondContact O-N 3.2Å; L24-L28 HydrophobicContact CD1-CD1 4.08Å; L24-L28 HydrophobicContact CD1-CG 4.49Å; L24-L28 HydrophobicContact CD2-CD1 4.37Å; L24-L28 HydrophobicContact CG-CD1 3.8Å; L24-L28 HydrophobicContact CG-CG 4.4Å; L24-L28 WeakPolarHBondContact O-CB 3.45Å; L24-L28 WeakPolarHBondContact O-CG 3.49Å; L24-L28 PolarHBondContact O-N 2.96Å; L24-L450 HydrophobicContact CD2-CD2 4.43Å
25	V	53.9	Low	53.1	Low	31 Å²	31	94 Å²	94	19%	0.188	55%	0.549	C	S	.	.	H	α-helix	trans	-65.6	-34	175.4	174.7	0	0	0	0	111.5	L21 L168 I171	L21-V25 WeakPolarHBondContact O-CB 3.33Å; L21-V25 VanDerWaalsContact O-CG2 3.3Å; L21-V25 WeakPolarHBondContact O-CG2 3.49Å; L21-V25 PolarHBondContact O-N 3.08Å; V25-L168 HydrophobicContact CG1-CD1 4.3Å; V25-I171 HydrophobicContact CG1-CD1 4.04Å; V25-I171 HydrophobicContact CG2-CD1 3.99Å
26	A	54.4	Low	52.6	Low	46 Å²	46	94.2 Å²	94.2	38%	0.38	55%	0.551	S	S	.	*	H	α-helix	trans	-77.6	-27.1	176.3	0	0	0	0	0	114.5	G22 L23 L24	G22-A26 WeakPolarHBondContact O-CB 3.37Å; G22-A26 PolarHBondContact O-N 2.85Å; L23-A26 PolarHBondContact O-N 3.46Å; L24-A26 VanDerWaalsContact C-N 3.32Å; L24-A26 PolarHBondContact O-N 2.88Å
27	G	45.5	Very low	51.8	Low	50 Å²	50	97.6 Å²	97.6	52%	0.515	57%	0.57	S	S	.	*	H	α-helix	trans	-95.6	-35.9	-173	0	0	0	0	0	114.5	L23 L24 G29 G30	L23-G27 WeakPolarHBondContact O-CA 3.37Å; L23-G27 PolarHBondContact O-N 3.22Å; L24-G27 PolarHBondContact O-N 3.2Å; G27-G29 VanDerWaalsContact C-N 3.31Å; G27-G29 PolarHBondContact O-N 3.06Å; G27-G30 PolarHBondContact O-N 3.24Å
28	L	52.8	Low	51	Low	104 Å²	104	100.3 Å²	100.3	55%	0.545	58%	0.581	S	S	.	*	H	α-helix	trans	-70.5	-27.3	178.9	-69.7	175.9	0	0	0	112.8	L24 G30	L24-L28 HydrophobicContact CD1-CD1 4.08Å; L24-L28 HydrophobicContact CD1-CG 4.49Å; L24-L28 HydrophobicContact CD2-CD1 4.37Å; L24-L28 HydrophobicContact CG-CD1 3.8Å; L24-L28 HydrophobicContact CG-CG 4.4Å; L24-L28 WeakPolarHBondContact O-CB 3.45Å; L24-L28 WeakPolarHBondContact O-CG 3.49Å; L24-L28 PolarHBondContact O-N 2.96Å; L28-G30 PolarHBondContact O-N 3.44Å
29	G	45.6	Very low	50	Low	57 Å²	57	103.4 Å²	103.4	59%	0.588	60%	0.599	S	S	*	*	T	Hydrogen-bonded Turn	trans	-80.2	11.8	174.6	0	0	0	0	0	115.2	G27	G27-G29 VanDerWaalsContact C-N 3.31Å; G27-G29 PolarHBondContact O-N 3.06Å
30	G	43.2	Very low	49.2	Very low	59 Å²	59	108.3 Å²	108.3	61%	0.608	61%	0.613	S	S	*	*	T	Hydrogen-bonded Turn	trans	-104.2	9	-178.4	0	0	0	0	0	115	G27 L28	G27-G30 PolarHBondContact O-N 3.24Å; L28-G30 PolarHBondContact O-N 3.44Å
31	H	46.8	Very low	48.2	Very low	170 Å²	170	110.3 Å²	110.3	79%	0.787	62%	0.621	S	S	*	*	S	Bend	trans	-128.5	2.8	-166.7	-139.3	-76.1	0	0	0	115.6
32	D	48.6	Very low	47.2	Very low	132 Å²	132	115.8 Å²	115.8	71%	0.706	64%	0.642	S	S	*	*	S	Bend	trans	-106.1	-6	-178.8	-69.1	-30.8	0	0	0	114	L34	D32-L34 VanDerWaalsContact C-N 3.26Å; D32-L34 PolarHBondContact O-N 3.04Å
33	D	46.8	Very low	46.5	Very low	154 Å²	154	122.8 Å²	122.8	82%	0.824	66%	0.664	S	S	*	*	S	Bend	trans	-85.7	27.4	-178.8	-73.3	-38.5	0	0	0	113.8
34	L	42.7	Very low	45.6	Very low	156 Å²	156	119.6 Å²	119.6	82%	0.817	66%	0.664	S	S	*	*			trans	-144.1	55.9	-178.1	-157.5	83.7	0	0	0	114.1	D32	D32-L34 VanDerWaalsContact C-N 3.26Å; D32-L34 PolarHBondContact O-N 3.04Å
35	H	47.1	Very low	45	Very low	170 Å²	170	124.6 Å²	124.6	79%	0.787	69%	0.685	S	S	*	*	S	Bend	trans	-138.2	105.6	161	-96.8	-66.6	0	0	0	113.5
36	D	43.7	Very low	44.2	Very low	120 Å²	120	128.1 Å²	128.1	64%	0.642	71%	0.711	S	S	*	*			trans	50.3	92	149.1	-58.9	-50	0	0	0	119.8	L38	D36-L38 HydrophobicContact CB-CB 4.4Å; D36-L38 HydrophobicContact CB-CD1 4.15Å; D36-L38 HydrophobicContact CB-CG 4.23Å; D36-L38 PolarHBondContact O-N 3.48Å
37	D	42	Very low	43.9	Very low	181 Å²	181	134.6 Å²	134.6	97%	0.968	73%	0.733	S	S	*	*			trans	-56.7	85.3	136.1	-78.5	-53.8	0	0	0	110
38	L	43.6	Very low	43.4	Very low	130 Å²	130	143.6 Å²	143.6	68%	0.681	75%	0.751	S	S	*	*			trans	-117.5	93.3	166.4	-87.4	171.5	0	0	0	111.3	D36 E40	D36-L38 HydrophobicContact CB-CB 4.4Å; D36-L38 HydrophobicContact CB-CD1 4.15Å; D36-L38 HydrophobicContact CB-CG 4.23Å; D36-L38 PolarHBondContact O-N 3.48Å; L38-E40 PolarHBondContact O-N 2.97Å; L38-E40 VanDerWaalsContact O-N 3.12Å
39	Q	38.7	Very low	43.1	Very low	162 Å²	162	146.8 Å²	146.8	76%	0.757	76%	0.763	S	S	*	*			trans	-65.9	97.1	165.5	177.1	-177.5	-31	0	0	109.9	D41	Q39-D41 PolarHBondContact NE2-OD2 3.45Å; Q39-D41 PolarHBondContact O-N 3.43Å
40	E	42.3	Very low	42.8	Very low	155 Å²	155	148.9 Å²	148.9	72%	0.724	77%	0.769	S	S	*	*			trans	-89.8	95.1	167.7	-72.5	-148.7	148.4	0	0	111.7	L38 F42	L38-E40 PolarHBondContact O-N 2.97Å; L38-E40 VanDerWaalsContact O-N 3.12Å; E40-F42 HydrophobicContact CB-CD2 4.47Å; E40-F42 PolarHBondContact O-N 3.17Å
41	D	40.7	Very low	43.2	Very low	123 Å²	123	155 Å²	155	66%	0.658	78%	0.781	S	S	*	*			trans	-71.4	97	166.1	-77.8	-57.5	0	0	0	110.9	Q39	Q39-D41 PolarHBondContact NE2-OD2 3.45Å; Q39-D41 PolarHBondContact O-N 3.43Å
42	F	40.9	Very low	42.9	Very low	174 Å²	174	154.9 Å²	154.9	76%	0.763	78%	0.781	S	S	*	*			trans	-106.6	94.3	171.1	-101.9	-77.7	0	0	0	113.4	E40	E40-F42 HydrophobicContact CB-CD2 4.47Å; E40-F42 PolarHBondContact O-N 3.17Å
43	H	41	Very low	42.9	Very low	188 Å²	188	155.1 Å²	155.1	87%	0.87	78%	0.782	S	S	*	*			trans	-75.1	117.7	159.1	-73.4	-47	0	0	0	110.1
44	G	40.3	Very low	42.6	Very low	70 Å²	70	156.2 Å²	156.2	72%	0.722	78%	0.78	S	S	*	*			trans	-147.5	93.7	-175.9	0	0	0	0	0	114
45	H	44.3	Very low	42.8	Very low	185 Å²	185	155.4 Å²	155.4	86%	0.856	77%	0.772	S	S	*	*			trans	-3	137.4	171.2	-62.3	-69.6	0	0	0	122.7
46	S	37.3	Very low	42.9	Very low	105 Å²	105	155.3 Å²	155.3	73%	0.734	77%	0.771	S	S	*	*			trans	-58.2	139.7	165.9	55.2	0	0	0	0	115.2
47	H	47.2	Very low	42.9	Very low	182 Å²	182	153.4 Å²	153.4	84%	0.843	78%	0.78	S	S	*	*			trans	-141.4	139.4	140.6	-91.7	-78	0	0	0	110.9
48	R	35.8	Very low	43.2	Very low	239 Å²	239	153.7 Å²	153.7	90%	0.902	78%	0.775	S	S	*	*			trans	-118.3	116.1	-176.2	177.5	-175	-177.1	-177.6	1.6	108
49	H	46.9	Very low	43.4	Very low	170 Å²	170	153.2 Å²	153.2	79%	0.787	78%	0.783	S	S	*	*			trans	-128.8	120.5	168.3	-85.2	-79.5	0	0	0	110.5
50	S	39.4	Very low	44.1	Very low	102 Å²	102	153.3 Å²	153.3	71%	0.713	78%	0.783	S	S	*	*			trans	-89.3	137.5	165.8	48	0	0	0	0	109.4
51	H	51.9	Low	44.4	Very low	186 Å²	186	150.9 Å²	150.9	86%	0.861	79%	0.789	S	S	*	*			trans	-139.2	121.2	154.5	-106.1	-80.7	0	0	0	108.3
52	E	41	Very low	44.9	Very low	168 Å²	168	152.6 Å²	152.6	79%	0.785	79%	0.793	S	S	*	*			trans	-94.5	173.4	168.1	-65.9	-178.4	119	0	0	109.8
53	D	47.4	Very low	45.1	Very low	137 Å²	137	148.2 Å²	148.2	73%	0.733	80%	0.797	S	S	*	*			trans	95.8	144.4	157.3	-53.5	-33	0	0	0	121.6
54	F	41.7	Very low	45.5	Very low	178 Å²	178	147.5 Å²	147.5	78%	0.781	79%	0.794	S	S	*	*			trans	89	73.9	164.2	-66.1	-76.7	0	0	0	121.8
55	H	45.4	Very low	45.5	Very low	138 Å²	138	147 Å²	147	64%	0.639	79%	0.789	S	S	*	*				52.4	117.8	112.2	-69.6	-73	0	0	0	122.9
56	H	50.1	Low	45.7	Very low	169 Å²	169	146.5 Å²	146.5	78%	0.782	79%	0.786	S	S	*	*			trans	62.4	123.2	136.9	-58	-52.2	0	0	0	122.6
57	G	43.5	Very low	45.9	Very low	80 Å²	80	148 Å²	148	83%	0.825	79%	0.791	S	S	*	*			trans	-164.8	87.6	157.6	0	0	0	0	0	112.3
58	H	47.8	Very low	46	Very low	187 Å²	187	147.9 Å²	147.9	87%	0.866	79%	0.791	S	S	*	*			trans	-87.2	136.1	167.2	-78.8	-61.7	0	0	0	110.3
59	S	48.2	Very low	46.4	Very low	119 Å²	119	144.6 Å²	144.6	83%	0.832	79%	0.786	S	S	*	*			trans	-145	136.1	156.4	54.3	0	0	0	0	110.2
60	H	52.9	Low	46.3	Very low	165 Å²	165	140.9 Å²	140.9	76%	0.764	78%	0.779	S	S	*	*			trans	-90.7	146.9	177.7	-74.5	-103.9	0	0	0	110.4
61	A	48.8	Very low	46.7	Very low	104 Å²	104	143.2 Å²	143.2	86%	0.86	78%	0.782	S	S	*	*			trans	-128.7	109.8	159.6	0	0	0	0	0	109.1
62	H	51.2	Low	46.3	Very low	159 Å²	159	146.2 Å²	146.2	74%	0.736	79%	0.786	S	S	*	*			trans	-86.8	127.3	167.9	-79.8	-93.6	0	0	0	109.3
63	G	44.2	Very low	46.9	Very low	82 Å²	82	146.5 Å²	146.5	85%	0.845	79%	0.787	S	S	*	*			trans	-113.2	112.6	166.8	0	0	0	0	0	110.2
64	H	50.2	Low	46.5	Very low	173 Å²	173	143.3 Å²	143.3	80%	0.801	79%	0.786	S	S	*	*			trans	-94.2	150.3	175	-86.7	-82	0	0	0	111.6
65	G	40.7	Very low	46.9	Very low	60 Å²	60	143 Å²	143	62%	0.619	79%	0.786	S	S	*	*			trans	75.6	143.4	159.7	0	0	0	0	0	114.7
66	H	48.4	Very low	46.9	Very low	173 Å²	173	142.9 Å²	142.9	80%	0.801	80%	0.795	S	S	*	*			cis	-155.7	152.1	24.7	-76.8	-87.9	0	0	0	110.4
67	T	41.9	Very low	47.3	Very low	137 Å²	137	141.4 Å²	141.4	84%	0.84	79%	0.789	S	S	*	*			trans	-70.5	132.5	162.6	45.8	0	0	0	0	109.9
68	H	48.4	Very low	47.4	Very low	180 Å²	180	145.2 Å²	145.2	83%	0.833	79%	0.79	S	S	*	*			trans	-121	127.8	163.5	-99.1	-86.6	0	0	0	110.1
69	E	44.4	Very low	48	Very low	170 Å²	170	144.1 Å²	144.1	79%	0.794	79%	0.785	S	S	*	*			trans	-81.7	163.8	173.1	-58.8	-178.6	131.1	0	0	111.2
70	S	45.8	Very low	47.9	Very low	92 Å²	92	144.7 Å²	144.7	64%	0.643	78%	0.778	S	S	*	*			trans	43.6	113.3	146.1	59.4	0	0	0	0	120.4
71	I	45.8	Very low	48	Very low	151 Å²	151	145 Å²	145	77%	0.774	78%	0.78	S	S	*	*			trans	-145.2	111.3	137.2	-88	131.4	0	0	0	107.4
72	W	43.7	Very low	47.8	Very low	249 Å²	249	143.7 Å²	143.7	94%	0.943	78%	0.777	S	S	*	*			trans	-176.9	64.5	144.2	-83.8	122.7	0	0	0	107.2
73	H	54	Low	47.7	Very low	174 Å²	174	145.4 Å²	145.4	81%	0.806	79%	0.785	S	S	*	*			trans	-122.3	129.3	175.3	-91.7	-64.6	0	0	0	110.3
74	G	39.7	Very low	47.7	Very low	69 Å²	69	146.6 Å²	146.6	71%	0.711	78%	0.78	S	S	*	*			trans	52.5	100.5	144.3	0	0	0	0	0	119.8
75	H	49	Very low	47.8	Very low	173 Å²	173	146.2 Å²	146.2	80%	0.801	78%	0.778	S	S	*	*			trans	-119.5	104.3	144.3	-76.7	-54.4	0	0	0	110.2
76	T	47.2	Very low	48.1	Very low	134 Å²	134	151 Å²	151	82%	0.822	79%	0.785	S	S	*	*			trans	-72.6	123.8	159.1	44.4	0	0	0	0	108.6
77	H	57.9	Low	48.1	Very low	139 Å²	139	149.3 Å²	149.3	64%	0.644	78%	0.782	S	S	*	*			trans	-108.1	95.7	168.7	-80.5	-90.8	0	0	0	109.4	H79	H77-H79 AromaticContact ND1-CD2 3.97Å; H77-H79 AromaticContact ND1-NE2 3.44Å; H77-H79 PolarHBondContact ND1-NE2 2.81Å
78	D	44.2	Very low	48.2	Very low	159 Å²	159	148.2 Å²	148.2	85%	0.85	77%	0.77	S	S	*	*			trans	-72.3	122.7	153.1	-79.7	-48.7	0	0	0	107.6
79	H	60.9	Low	48.3	Very low	165 Å²	165	149.1 Å²	149.1	76%	0.764	77%	0.774	S	S	*	*			trans	-124.9	124.1	166.2	-86.1	-60.3	0	0	0	109.8	H77	H77-H79 AromaticContact ND1-CD2 3.97Å; H77-H79 AromaticContact ND1-NE2 3.44Å; H77-H79 PolarHBondContact ND1-NE2 2.81Å
80	D	45.7	Very low	48.7	Very low	130 Å²	130	149.1 Å²	149.1	70%	0.695	77%	0.774	S	S	*	*			trans	-90.4	150.9	-164.1	-134.2	-14.1	0	0	0	113
81	H	55.9	Low	48.6	Very low	172 Å²	172	148 Å²	148	80%	0.796	78%	0.776	S	S	*	*			trans	63.9	126.3	152.3	-60.9	-11	0	0	0	121
82	G	44	Very low	48.7	Very low	77 Å²	77	149.7 Å²	149.7	79%	0.794	78%	0.781	S	S	*	*			trans	177.3	61.3	166.7	0	0	0	0	0	115.1
83	H	49.9	Very low	48.6	Very low	195 Å²	195	142.8 Å²	142.8	90%	0.903	77%	0.771	S	S	*	*			trans	-108.6	122.9	174.6	-77.1	-62	0	0	0	113
84	S	43.9	Very low	48.7	Very low	107 Å²	107	143.5 Å²	143.5	75%	0.748	77%	0.774	S	S	*	*			trans	-167.2	126.1	148.4	23.6	0	0	0	0	109.6
85	H	53.3	Low	48.7	Very low	165 Å²	165	143.4 Å²	143.4	76%	0.764	77%	0.773	S	S	*	*				55.1	128.3	102.7	-69.5	-93.1	0	0	0	113.1
86	E	45.3	Very low	48.4	Very low	161 Å²	161	146 Å²	146	75%	0.752	78%	0.778	S	S	*	*			cis	-154.6	-173.5	13.8	-116.9	138.7	-152.2	0	0	107.8
87	D	49.4	Very low	48.1	Very low	137 Å²	137	144.9 Å²	144.9	73%	0.733	78%	0.775	S	S	*	*			cis	-151.7	-178	21.7	-163.5	10.6	0	0	0	112.3
88	L	43.2	Very low	47.7	Very low	113 Å²	113	147.5 Å²	147.5	59%	0.592	79%	0.787	S	S	*	*			trans	-62.9	153.2	176.4	-83.2	49.5	0	0	0	117.3
89	H	51.3	Low	47.5	Very low	199 Å²	199	148.3 Å²	148.3	92%	0.921	79%	0.786	S	S	*	*				-149.1	123.3	129.7	-88.7	-61.6	0	0	0	111.9
90	H	52.5	Low	46.7	Very low	171 Å²	171	144.8 Å²	144.8	79%	0.792	78%	0.78	S	S	*	*			trans	-115.9	156.9	176	-73.2	-66.9	0	0	0	111.7
91	G	43.8	Very low	46.5	Very low	68 Å²	68	146.5 Å²	146.5	70%	0.701	79%	0.788	S	S	*	*			trans	151.4	87.7	165.9	0	0	0	0	0	112.1
92	H	48.6	Very low	45.8	Very low	186 Å²	186	147.9 Å²	147.9	86%	0.861	79%	0.788	S	S	*	*				83.9	123.3	81.1	-77.6	10.9	0	0	0	115
93	S	40.6	Very low	46.1	Very low	105 Å²	105	153.9 Å²	153.9	73%	0.734	80%	0.795	S	S	*	*			trans	-99.8	137.6	-178.4	53.1	0	0	0	0	112
94	H	55.5	Low	45.7	Very low	188 Å²	188	156 Å²	156	87%	0.87	80%	0.795	S	S	*	*			trans	-144.4	135.2	154	-79.1	-71.8	0	0	0	109.7
95	G	40.6	Very low	45.7	Very low	68 Å²	68	153.9 Å²	153.9	70%	0.701	79%	0.79	S	S	*	*			trans	-103.9	157.2	174.5	0	0	0	0	0	111.7
96	Y	43.2	Very low	45.6	Very low	228 Å²	228	154.8 Å²	154.8	89%	0.894	79%	0.794	S	S	*	*			trans	-141.1	126.9	159.7	-89.3	-78.2	0	0	0	109.8
97	S	41	Very low	45.5	Very low	110 Å²	110	150.5 Å²	150.5	77%	0.769	79%	0.793	S	S	*	*			trans	-81.5	144.4	166.5	49.4	0	0	0	0	110.3
98	H	48	Very low	45.8	Very low	193 Å²	193	151 Å²	151	89%	0.894	79%	0.791	S	S	*	*			trans	-136.6	135.5	160.2	-122.1	-85.3	0	0	0	110.8
99	E	41.5	Very low	45.8	Very low	176 Å²	176	153.6 Å²	153.6	82%	0.822	81%	0.805	S	S	*	*			trans	-80.5	155.5	-171.9	-77	179.3	96.4	0	0	114.3
100	S	42.6	Very low	46.1	Very low	92 Å²	92	151 Å²	151	64%	0.643	79%	0.793	S	S	*	*			trans	23.9	126.4	147	69.9	0	0	0	0	120.3
101	L	41.4	Very low	45.7	Very low	165 Å²	165	152.8 Å²	152.8	86%	0.864	80%	0.802	S	S	*	*				-155.1	142.1	121.6	-114	145.3	0	0	0	112.3
102	Y	43.1	Very low	46.1	Very low	202 Å²	202	156.7 Å²	156.7	79%	0.792	80%	0.801	S	S	*	*			trans	-62	141.1	-177.5	-59.6	-101.1	0	0	0	112.2
103	H	49.5	Very low	45.7	Very low	202 Å²	202	153.7 Å²	153.7	94%	0.935	80%	0.801	S	S	*	*			trans	-155.2	147.4	130.8	-104.5	-70.7	0	0	0	111.4
104	R	41.5	Very low	46.5	Very low	240 Å²	240	156.8 Å²	156.8	91%	0.906	80%	0.804	S	S	*	*			trans	-122.2	127.6	-168	171.7	179.8	179.3	157.9	0	110
105	G	43.6	Very low	45.7	Very low	62 Å²	62	151.8 Å²	151.8	64%	0.639	80%	0.803	S	S	*	*			trans	84.1	118.1	164.3	0	0	0	0	0	115.4
106	H	50.7	Low	45.8	Very low	184 Å²	184	151.9 Å²	151.9	85%	0.852	80%	0.804	S	S	*	*				-173.7	134	106.3	-95.3	-73.8	0	0	0	108.2
107	G	42.8	Very low	45.8	Very low	72 Å²	72	152.8 Å²	152.8	74%	0.742	81%	0.808	S	S	*	*			trans	-85.3	136	176	0	0	0	0	0	110.7
108	H	55.9	Low	45.6	Very low	148 Å²	148	150.8 Å²	150.8	69%	0.685	81%	0.805	S	S	*	*			trans	-142.5	116.4	164.6	-81.1	-72.2	0	0	0	108.8
109	D	44.8	Very low	45.5	Very low	167 Å²	167	151.1 Å²	151.1	89%	0.893	81%	0.807	S	S	*	*			trans	-70.3	126	170.6	-55.9	-62.4	0	0	0	109.1
110	H	56.4	Low	45.2	Very low	145 Å²	145	148.8 Å²	148.8	67%	0.671	81%	0.81	S	S	*	*			trans	-127.7	91.7	175	-79.4	-63.4	0	0	0	110.2	H112	H110-H112 PolarHBondContact O-N 2.82Å
111	E	43.4	Very low	44.9	Very low	207 Å²	207	147.7 Å²	147.7	97%	0.967	81%	0.814	S	S	*	*			trans	-71.2	107.7	166.1	-118.4	177.1	105	0	0	109.3
112	H	52.9	Low	44.8	Very low	150 Å²	150	144 Å²	144	69%	0.694	81%	0.806	S	S	*	*			trans	-91.2	110.1	175.1	-79.9	-78.5	0	0	0	110.7	H110 H114	H110-H112 PolarHBondContact O-N 2.82Å; H112-H114 PolarHBondContact O-N 3.45Å
113	S	41.1	Very low	44.7	Very low	123 Å²	123	139.9 Å²	139.9	86%	0.86	80%	0.804	S	S	*	*			trans	-71	116.7	172.2	-168.9	0	0	0	0	110.6
114	H	56.8	Low	44.3	Very low	171 Å²	171	133.8 Å²	133.8	79%	0.792	80%	0.797	S	S	*	*			trans	-108.8	112.7	166.8	-80.8	-79.6	0	0	0	109.6	H112 G116	H112-H114 PolarHBondContact O-N 3.45Å; H114-G116 PolarHBondContact O-N 3.46Å
115	G	39.3	Very low	44.5	Very low	82 Å²	82	129.4 Å²	129.4	85%	0.845	79%	0.79	S	S	*	*			trans	-69.7	117.9	171.4	0	0	0	0	0	110.9
116	G	42	Very low	44.9	Very low	71 Å²	71	134.8 Å²	134.8	73%	0.732	80%	0.795	S	S	*	*			trans	-119.4	126.4	169.1	0	0	0	0	0	109.8	H114 G118	H114-G116 PolarHBondContact O-N 3.46Å; G116-G118 PolarHBondContact O-N 2.89Å
117	Y	42.7	Very low	45.1	Very low	246 Å²	246	131.3 Å²	131.3	97%	0.965	78%	0.779	S	S	*	*			trans	-70.2	98.5	171.5	-69.8	-96	0	0	0	108.7
118	G	38.4	Very low	46.1	Very low	69 Å²	69	135.2 Å²	135.2	71%	0.711	78%	0.783	S	S	*	*			trans	-98.1	117.4	176.7	0	0	0	0	0	111.5	G116 S120	G116-G118 PolarHBondContact O-N 2.89Å; G118-S120 PolarHBondContact O-N 2.91Å
119	E	43.9	Very low	47.1	Very low	200 Å²	200	130 Å²	130	94%	0.935	76%	0.76	S	S	*	*			trans	-62	131.2	164.5	-73.9	-177.7	102.9	0	0	109.7	G121	E119-G121 PolarHBondContact O-N 3.38Å
120	S	35.8	Very low	49	Very low	126 Å²	126	126.2 Å²	126.2	88%	0.881	74%	0.74	S	S	*	*			trans	-79	69.3	-172.7	-166	0	0	0	0	112.1	G118 A122	G118-S120 PolarHBondContact O-N 2.91Å; S120-A122 PolarHBondContact O-N 2.68Å
121	G	37.8	Very low	50.5	Low	70 Å²	70	122.5 Å²	122.5	72%	0.722	74%	0.735	S	S	*	*			trans	-77.7	96	166.4	0	0	0	0	0	110.2	E119	E119-G121 PolarHBondContact O-N 3.38Å
122	A	37.8	Very low	52.8	Low	86 Å²	86	118.1 Å²	118.1	71%	0.711	72%	0.722	S	S	*	*			trans	-63.6	132.7	179.1	0	0	0	0	0	111.3	S120 G124	S120-A122 PolarHBondContact O-N 2.68Å; A122-G124 PolarHBondContact O-N 3.48Å
123	P	42.3	Very low	54.6	Low	116 Å²	116	113 Å²	113	75%	0.753	70%	0.701	S	S	*	*			trans	-66.2	127.2	173.2	28.1	-33	0	0	0	108.8	I125	P123-I125 PolarHBondContact O-N 2.75Å
124	G	41.2	Very low	57.1	Low	75 Å²	75	108 Å²	108	77%	0.773	67%	0.665	S	S	*	*			trans	-59.8	108.2	-179.6	0	0	0	0	0	111	A122 K126	A122-G124 PolarHBondContact O-N 3.48Å; G124-K126 PolarHBondContact O-N 2.89Å
125	I	44.7	Very low	58.8	Low	148 Å²	148	104 Å²	104	76%	0.759	64%	0.642	S	S	*	*			trans	-61.5	107.8	170.2	-61.4	176.7	0	0	0	106.6	P123 Q127	P123-I125 PolarHBondContact O-N 2.75Å; I125-Q127 HydrophobicContact CG2-CG 4.12Å; I125-Q127 PolarHBondContact O-N 3.18Å
126	K	52	Low	61.5	Low	174 Å²	174	102.9 Å²	102.9	76%	0.757	63%	0.625	S	S	*	*			trans	-61.6	96	162.7	-70.1	-171.6	176.5	-171.3	0	106.5	G124 D128	G124-K126 PolarHBondContact O-N 2.89Å; K126-D128 VanDerWaalsContact C-N 3.28Å; K126-D128 PolarHBondContact O-N 3.2Å
127	Q	54.8	Low	64	Low	111 Å²	111	104.2 Å²	104.2	52%	0.519	61%	0.609	S	S	.	*			trans	-72.8	92	171	-67	-171.5	-55.2	0	0	106.5	I125 L129	I125-Q127 HydrophobicContact CG2-CG 4.12Å; I125-Q127 PolarHBondContact O-N 3.18Å; Q127-L129 PolarHBondContact O-N 3.09Å
128	D	64.8	Low	66.5	Low	154 Å²	154	92.5 Å²	92.5	82%	0.824	56%	0.563	S	S	*	*			trans	-55.9	109	168.5	-73.8	-22.6	0	0	0	107.7	K126	K126-D128 VanDerWaalsContact C-N 3.28Å; K126-D128 PolarHBondContact O-N 3.2Å
129	L	75.4	Confident	69.2	Low	39 Å²	39	91.9 Å²	91.9	20%	0.204	54%	0.543	C	S	.	.			trans	-68.1	133.1	172.8	-66.5	164.9	0	0	0	107.1	Q127 T133 L134 Y137 F341 R345	Q127-L129 PolarHBondContact O-N 3.09Å; L129-T133 HydrophobicContact CD2-CG2 3.92Å; L129-L134 HydrophobicContact CB-CB 3.96Å; L129-L134 HydrophobicContact CD1-CD1 4.05Å; L129-Y137 HydrophobicContact CD1-CD2 4.12Å; L129-Y137 HydrophobicContact CD2-CD2 3.95Å; L129-Y137 HydrophobicContact CD2-CE2 3.74Å; L129-F341 HydrophobicContact CD1-CD1 4.49Å; L129-R345 HydrophobicContact CD1-CB 4.16Å; L129-R345 HydrophobicContact CD2-CB 4.34Å
130	D	86.3	Confident	71.7	Confident	87 Å²	87	84.3 Å²	84.3	47%	0.465	52%	0.519	S	S	.	.			trans	-59.6	153.2	167.5	72.5	-90.7	0	0	0	109.5	V132 T133 L134	D130-V132 PolarHBondContact O-N 3.25Å; D130-V132 VanDerWaalsContact O-N 3.11Å; D130-V132 WeakPolarHBondContact OD2-CA 3.26Å; D130-V132 WeakPolarHBondContact OD2-CB 3.42Å; D130-V132 PolarHBondContact OD2-N 3.34Å; D130-T133 PolarHBondContact O-N 2.99Å; D130-T133 VanDerWaalsContact O-N 3.13Å; D130-T133 WeakPolarHBondContact OD1-CB 3.11Å; D130-T133 PolarHBondContact OD1-OG1 3.23Å; D130-T133 PolarHBondContact OD2-N 3.48Å; D130-T133 PolarHBondContact OD2-OG1 2.79Å; D130-L134 WeakPolarHBondContact O-CB 3.41Å; D130-L134 PolarHBondContact O-N 3.21Å
131	A	87.7	Confident	74.6	Confident	68 Å²	68	78.8 Å²	78.8	56%	0.562	48%	0.481	S	S	*	.	H	α-helix	trans	-57.5	-32.9	-172.4	0	0	0	0	0	113.3	W135	A131-W135 WeakPolarHBondContact O-CB 3.15Å; A131-W135 PolarHBondContact O-N 3.21Å; A131-W135 VanDerWaalsContact O-N 3.12Å
132	V	90.6	Very high	77.3	Confident	115 Å²	115	75.4 Å²	75.4	70%	0.697	45%	0.446	S	S	*	.	H	α-helix	trans	-72.7	-45.8	179.7	-177.6	0	0	0	0	110.2	D130 W135 A136	D130-V132 PolarHBondContact O-N 3.25Å; D130-V132 VanDerWaalsContact O-N 3.11Å; D130-V132 WeakPolarHBondContact OD2-CA 3.26Å; D130-V132 WeakPolarHBondContact OD2-CB 3.42Å; D130-V132 PolarHBondContact OD2-N 3.34Å; V132-W135 PolarHBondContact O-N 2.83Å; V132-A136 VanDerWaalsContact O-CB 3.27Å; V132-A136 WeakPolarHBondContact O-CB 3.46Å; V132-A136 PolarHBondContact O-N 2.84Å
133	T	92.2	Very high	80	Confident	41 Å²	41	75.2 Å²	75.2	25%	0.252	44%	0.436	S	S	.	.	H	α-helix	trans	-64.9	-38.9	176.4	-57.7	0	0	0	0	111.9	L129 D130 A136 Y137	L129-T133 HydrophobicContact CD2-CG2 3.92Å; D130-T133 PolarHBondContact O-N 2.99Å; D130-T133 VanDerWaalsContact O-N 3.13Å; D130-T133 WeakPolarHBondContact OD1-CB 3.11Å; D130-T133 PolarHBondContact OD1-OG1 3.23Å; D130-T133 PolarHBondContact OD2-N 3.48Å; D130-T133 PolarHBondContact OD2-OG1 2.79Å; T133-A136 PolarHBondContact O-N 3.45Å; T133-Y137 HydrophobicContact CG2-CD1 4.23Å; T133-Y137 HydrophobicContact CG2-CD2 3.88Å; T133-Y137 HydrophobicContact CG2-CE1 3.88Å; T133-Y137 HydrophobicContact CG2-CE2 3.49Å; T133-Y137 VanDerWaalsContact CG2-CE2 3.49Å; T133-Y137 HydrophobicContact CG2-CG 4.24Å; T133-Y137 VanDerWaalsContact CG2-CZ 3.5Å; T133-Y137 WeakPolarHBondContact O-CB 3.5Å; T133-Y137 PolarHBondContact O-N 3.09Å
134	L	91.8	Very high	82.5	Confident	19 Å²	19	73.8 Å²	73.8	10%	0.099	42%	0.422	C	S	.	.	H	α-helix	trans	-57.2	-53.5	174.7	174.4	63.6	0	0	0	111.3	L129 D130 Y137 A138 F341 R342 L399	L129-L134 HydrophobicContact CB-CB 3.96Å; L129-L134 HydrophobicContact CD1-CD1 4.05Å; D130-L134 WeakPolarHBondContact O-CB 3.41Å; D130-L134 PolarHBondContact O-N 3.21Å; L134-Y137 PolarHBondContact O-N 3.46Å; L134-A138 WeakPolarHBondContact O-CB 3.44Å; L134-A138 PolarHBondContact O-N 3.27Å; L134-F341 HydrophobicContact CD1-CB 3.87Å; L134-F341 WeakPolarHBondContact CD1-O 3.46Å; L134-R342 HydrophobicContact CD2-CG 4.4Å; L134-L399 HydrophobicContact CD1-CD2 4.21Å; L134-L399 HydrophobicContact CD2-CD2 4.08Å; L134-L399 HydrophobicContact CG-CD2 3.86Å
135	W	94.1	Very high	84.9	Confident	86 Å²	86	70.2 Å²	70.2	33%	0.326	39%	0.385	S	S	.	.	H	α-helix	trans	-63.5	-41.2	178.7	-83.7	68.9	0	0	0	111.9	A131 V132 L139 L399 L400	A131-W135 WeakPolarHBondContact O-CB 3.15Å; A131-W135 PolarHBondContact O-N 3.21Å; A131-W135 VanDerWaalsContact O-N 3.12Å; V132-W135 PolarHBondContact O-N 2.83Å; W135-L139 HydrophobicContact CE3-CD1 4Å; W135-L139 VanDerWaalsContact O-CB 3.27Å; W135-L139 WeakPolarHBondContact O-CB 3.42Å; W135-L139 WeakPolarHBondContact O-CG 3.39Å; W135-L139 PolarHBondContact O-N 3.45Å; W135-L399 HydrophobicContact CB-CD1 4.46Å; W135-L399 HydrophobicContact CD2-CB 4.24Å; W135-L399 HydrophobicContact CD2-CD1 3.68Å; W135-L399 HydrophobicContact CE3-CD1 3.89Å; W135-L399 HydrophobicContact CG-CD1 3.93Å; W135-L399 HydrophobicContact CH2-CB 4.19Å; W135-L399 HydrophobicContact CZ2-CB 3.64Å; W135-L399 HydrophobicContact CZ2-CD1 4.48Å; W135-L399 HydrophobicContact CZ3-CD1 4.37Å; W135-L400 HydrophobicContact CH2-CD2 3.87Å; W135-L400 HydrophobicContact CH2-CG 3.84Å; W135-L400 HydrophobicContact CZ2-CD2 3.89Å; W135-L400 HydrophobicContact CZ2-CG 4.03Å
136	A	95.1	Very high	87.1	Confident	59 Å²	59	63.6 Å²	63.6	49%	0.488	35%	0.352	S	S	.	.	H	α-helix	trans	-63.9	-40.6	178.2	0	0	0	0	0	112.7	V132 T133 G140	V132-A136 VanDerWaalsContact O-CB 3.27Å; V132-A136 WeakPolarHBondContact O-CB 3.46Å; V132-A136 PolarHBondContact O-N 2.84Å; T133-A136 PolarHBondContact O-N 3.45Å; A136-G140 WeakPolarHBondContact O-CA 3.29Å; A136-G140 PolarHBondContact O-N 3.01Å
137	Y	94.8	Very high	88.9	Confident	99 Å²	99	57 Å²	57	39%	0.388	33%	0.329	S	S	.	.	H	α-helix	trans	-70.8	-47	177.5	-72.9	-7	0	0	0	112.2	L129 T133 L134 G140 A141 F341 R345	L129-Y137 HydrophobicContact CD1-CD2 4.12Å; L129-Y137 HydrophobicContact CD2-CD2 3.95Å; L129-Y137 HydrophobicContact CD2-CE2 3.74Å; T133-Y137 HydrophobicContact CG2-CD1 4.23Å; T133-Y137 HydrophobicContact CG2-CD2 3.88Å; T133-Y137 HydrophobicContact CG2-CE1 3.88Å; T133-Y137 HydrophobicContact CG2-CE2 3.49Å; T133-Y137 VanDerWaalsContact CG2-CE2 3.49Å; T133-Y137 HydrophobicContact CG2-CG 4.24Å; T133-Y137 VanDerWaalsContact CG2-CZ 3.5Å; T133-Y137 WeakPolarHBondContact O-CB 3.5Å; T133-Y137 PolarHBondContact O-N 3.09Å; L134-Y137 PolarHBondContact O-N 3.46Å; Y137-G140 PolarHBondContact O-N 2.91Å; Y137-A141 VanDerWaalsContact O-CB 3.28Å; Y137-A141 WeakPolarHBondContact O-CB 3.07Å; Y137-A141 PolarHBondContact O-N 2.96Å; Y137-F341 HydrophobicContact CD2-CE1 4.33Å; Y137-F341 HydrophobicContact CG-CE1 4.4Å; Y137-R345 HydrophobicContact CD2-CG 4.28Å; Y137-R345 HydrophobicContact CE2-CG 4.14Å
138	A	94.3	Very high	90.3	Very high	0 Å²	0	52.7 Å²	52.7	0%	0	31%	0.313	C	S	.	.	H	α-helix	trans	-65.1	-46.6	180	0	0	0	0	0	112.1	L134 A141 T142 F341 T395 L399	L134-A138 WeakPolarHBondContact O-CB 3.44Å; L134-A138 PolarHBondContact O-N 3.27Å; A138-A141 PolarHBondContact O-N 3.21Å; A138-T142 WeakPolarHBondContact O-CB 3.4Å; A138-T142 PolarHBondContact O-N 3.49Å; A138-T142 PolarHBondContact O-OG1 3.2Å; A138-F341 HydrophobicContact CB-CB 4.11Å; A138-F341 HydrophobicContact CB-CD2 3.97Å; A138-F341 HydrophobicContact CB-CG 4.2Å; A138-T395 HydrophobicContact CB-CG2 3.82Å; A138-L399 HydrophobicContact CB-CD1 3.92Å; A138-L399 HydrophobicContact CB-CD2 4.17Å; A138-L399 HydrophobicContact CB-CG 4.43Å
139	L	96.2	Very high	91.1	Very high	56 Å²	56	45.4 Å²	45.4	29%	0.293	27%	0.274	S	S	.	.	H	α-helix	trans	-67.2	-37.6	175	-67.1	175.6	0	0	0	112.1	W135 T142 V143 L392 T395	W135-L139 HydrophobicContact CE3-CD1 4Å; W135-L139 VanDerWaalsContact O-CB 3.27Å; W135-L139 WeakPolarHBondContact O-CB 3.42Å; W135-L139 WeakPolarHBondContact O-CG 3.39Å; W135-L139 PolarHBondContact O-N 3.45Å; L139-T142 PolarHBondContact O-N 2.76Å; L139-V143 WeakPolarHBondContact O-CG2 3.41Å; L139-V143 PolarHBondContact O-N 2.93Å; L139-L392 HydrophobicContact CD2-CD2 4.08Å; L139-T395 HydrophobicContact CD2-CG2 4Å
140	G	96.4	Very high	91.5	Very high	42 Å²	42	47.5 Å²	47.5	43%	0.433	28%	0.282	S	S	.	.	H	α-helix	trans	-63.4	-41.1	175.9	0	0	0	0	0	112.9	A136 Y137 L144	A136-G140 WeakPolarHBondContact O-CA 3.29Å; A136-G140 PolarHBondContact O-N 3.01Å; Y137-G140 PolarHBondContact O-N 2.91Å; G140-L144 WeakPolarHBondContact O-CB 3.38Å; G140-L144 PolarHBondContact O-N 3.37Å
141	A	95.8	Very high	91.4	Very high	9 Å²	9	50.4 Å²	50.4	7%	0.074	29%	0.291	C	S	.	.	H	α-helix	trans	-63.6	-42.9	171.3	0	0	0	0	0	112.3	Y137 A138 L144 I145 I337 F341 T352	Y137-A141 VanDerWaalsContact O-CB 3.28Å; Y137-A141 WeakPolarHBondContact O-CB 3.07Å; Y137-A141 PolarHBondContact O-N 2.96Å; A138-A141 PolarHBondContact O-N 3.21Å; A141-L144 WeakPolarHBondContact O-CB 3.42Å; A141-L144 PolarHBondContact O-N 3.08Å; A141-L144 VanDerWaalsContact O-N 3.12Å; A141-I145 PolarHBondContact O-N 3.05Å; A141-I337 HydrophobicContact CB-CG2 3.89Å; A141-F341 HydrophobicContact CB-CE2 3.53Å; A141-F341 HydrophobicContact CB-CZ 4.08Å; A141-T352 HydrophobicContact CB-CG2 3.64Å; A141-T352 VanDerWaalsContact CB-OG1 3.32Å; A141-T352 WeakPolarHBondContact CB-OG1 3.09Å
142	T	95.4	Very high	91.1	Very high	0 Å²	0	49.4 Å²	49.4	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-61.4	-45.9	177.2	-49.3	0	0	0	0	111.4	A138 L139 L144 I145 S146 A391 L392 T395	A138-T142 WeakPolarHBondContact O-CB 3.4Å; A138-T142 PolarHBondContact O-N 3.49Å; A138-T142 PolarHBondContact O-OG1 3.2Å; L139-T142 PolarHBondContact O-N 2.76Å; T142-L144 VanDerWaalsContact C-N 3.27Å; T142-L144 PolarHBondContact O-N 3.38Å; T142-I145 WeakPolarHBondContact O-CG1 3.4Å; T142-I145 PolarHBondContact O-N 3.41Å; T142-S146 PolarHBondContact O-N 2.98Å; T142-S146 PolarHBondContact O-OG 3.28Å; T142-A391 VanDerWaalsContact CG2-C 3.47Å; T142-A391 HydrophobicContact CG2-CB 3.58Å; T142-L392 HydrophobicContact CG2-CD2 3.83Å; T142-L392 HydrophobicContact CG2-CG 4.15Å; T142-T395 WeakPolarHBondContact OG1-CB 3.43Å; T142-T395 WeakPolarHBondContact OG1-CG2 3.21Å; T142-T395 PolarHBondContact OG1-OG1 3.41Å
143	V	94.8	Very high	90.7	Very high	82 Å²	82	44 Å²	44	50%	0.497	25%	0.245	S	C	.	.	H	α-helix	trans	-64.2	-33.7	174.8	172.5	0	0	0	0	111.5	L139 A147 L392	L139-V143 WeakPolarHBondContact O-CG2 3.41Å; L139-V143 PolarHBondContact O-N 2.93Å; V143-A147 WeakPolarHBondContact O-CB 3.37Å; V143-A147 PolarHBondContact O-N 3.36Å; V143-L392 HydrophobicContact CG2-CD2 4.06Å
144	L	93.5	Very high	90.1	Very high	85 Å²	85	49 Å²	49	45%	0.445	26%	0.263	S	S	.	.	H	α-helix	trans	-66.3	-46.6	177	-179.9	65	0	0	0	112.1	G140 A141 T142 S146 A147 A148	G140-L144 WeakPolarHBondContact O-CB 3.38Å; G140-L144 PolarHBondContact O-N 3.37Å; A141-L144 WeakPolarHBondContact O-CB 3.42Å; A141-L144 PolarHBondContact O-N 3.08Å; A141-L144 VanDerWaalsContact O-N 3.12Å; T142-L144 VanDerWaalsContact C-N 3.27Å; T142-L144 PolarHBondContact O-N 3.38Å; L144-S146 PolarHBondContact O-N 2.81Å; L144-A147 PolarHBondContact O-N 2.91Å; L144-A148 WeakPolarHBondContact O-CB 3.4Å; L144-A148 PolarHBondContact O-N 3Å
145	I	92.4	Very high	89.5	Confident	0 Å²	0	54.8 Å²	54.8	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-62.9	-42.3	179.6	61.4	159.4	0	0	0	111.5	A141 T142 P149 D333 I337 T352 V355 L356	A141-I145 PolarHBondContact O-N 3.05Å; T142-I145 WeakPolarHBondContact O-CG1 3.4Å; T142-I145 PolarHBondContact O-N 3.41Å; I145-P149 WeakPolarHBondContact O-CD 3.44Å; I145-P149 WeakPolarHBondContact O-CG 3.32Å; I145-D333 HydrophobicContact CD1-CB 4.29Å; I145-I337 HydrophobicContact CD1-CD1 3.6Å; I145-I337 HydrophobicContact CG1-CD1 4.15Å; I145-I337 HydrophobicContact CG2-CD1 4.08Å; I145-T352 HydrophobicContact CG2-CG2 4.05Å; I145-V355 HydrophobicContact CB-CG1 4.36Å; I145-V355 HydrophobicContact CD1-CG1 3.61Å; I145-V355 HydrophobicContact CG2-CB 4.49Å; I145-V355 HydrophobicContact CG2-CG1 4.07Å; I145-L356 HydrophobicContact CG2-CB 4.18Å
146	S	91.1	Very high	88.7	Confident	9 Å²	9	51.5 Å²	51.5	6%	0.063	28%	0.282	C	S	.	.	H	α-helix	trans	-79.4	-19.5	-179.5	-45.4	0	0	0	0	113.5	T142 L144 A388	T142-S146 PolarHBondContact O-N 2.98Å; T142-S146 PolarHBondContact O-OG 3.28Å; L144-S146 PolarHBondContact O-N 2.81Å; S146-A388 VanDerWaalsContact CB-CB 3.45Å
147	A	88.8	Confident	87.5	Confident	35 Å²	35	53.7 Å²	53.7	29%	0.289	29%	0.292	S	S	.	.	H	α-helix	trans	-88.3	-29.7	177.3	0	0	0	0	0	113.2	V143 L144 F150 F151	V143-A147 WeakPolarHBondContact O-CB 3.37Å; V143-A147 PolarHBondContact O-N 3.36Å; L144-A147 PolarHBondContact O-N 2.91Å; A147-F150 WeakPolarHBondContact O-CB 3.32Å; A147-F150 PolarHBondContact O-N 2.97Å; A147-F151 WeakPolarHBondContact O-CD2 3.47Å; A147-F151 WeakPolarHBondContact O-CE2 3.35Å
148	A	85.3	Confident	86.2	Confident	22 Å²	22	49.5 Å²	49.5	18%	0.182	28%	0.276	C	S	.	.	H	α-helix	trans	-63.7	-44.8	-176.1	0	0	0	0	0	114.2	L144 F150 F151 L356	L144-A148 WeakPolarHBondContact O-CB 3.4Å; L144-A148 PolarHBondContact O-N 3Å; A148-F150 VanDerWaalsContact C-N 3.26Å; A148-F150 PolarHBondContact O-N 3.19Å; A148-F151 PolarHBondContact O-N 3.45Å; A148-F151 VanDerWaalsContact O-N 3.14Å; A148-L356 HydrophobicContact CB-CD1 3.44Å; A148-L356 VanDerWaalsContact CB-CD1 3.44Å
149	P	80.6	Confident	84.6	Confident	1 Å²	1	56.2 Å²	56.2	1%	0.006	31%	0.308	C	S	.	.	H	α-helix	trans	-57	-37.1	175.3	-25.8	33.4	0	0	0	113.1	I145 F151 V152 L153 V360 E363	I145-P149 WeakPolarHBondContact O-CD 3.44Å; I145-P149 WeakPolarHBondContact O-CG 3.32Å; P149-F151 PolarHBondContact O-N 3.41Å; P149-F151 VanDerWaalsContact O-N 3.16Å; P149-V152 WeakPolarHBondContact O-CA 3.45Å; P149-V152 WeakPolarHBondContact O-CB 3.43Å; P149-V152 PolarHBondContact O-N 3.24Å; P149-L153 WeakPolarHBondContact O-CG 3.15Å; P149-L153 PolarHBondContact O-N 3.19Å; P149-V360 HydrophobicContact CG-CG2 4.08Å; P149-E363 HydrophobicContact CB-CB 3.49Å; P149-E363 VanDerWaalsContact CB-CB 3.49Å; P149-E363 HydrophobicContact CB-CG 3.69Å; P149-E363 HydrophobicContact CG-CB 4.04Å; P149-E363 HydrophobicContact CG-CG 3.79Å
150	F	85.1	Confident	82.6	Confident	82 Å²	82	57 Å²	57	36%	0.36	32%	0.318	S	S	.	.	H	α-helix	trans	-55.4	-35.6	177.7	-169.9	-87.3	0	0	0	113	A147 A148 F154 M381	A147-F150 WeakPolarHBondContact O-CB 3.32Å; A147-F150 PolarHBondContact O-N 2.97Å; A148-F150 VanDerWaalsContact C-N 3.26Å; A148-F150 PolarHBondContact O-N 3.19Å; F150-F154 PolarHBondContact O-N 3.17Å; F150-F154 VanDerWaalsContact O-N 3.14Å; F150-M381 HydrophobicContact CD1-CE 4.21Å; F150-M381 HydrophobicContact CD2-CB 4.31Å; F150-M381 HydrophobicContact CD2-CE 3.92Å; F150-M381 HydrophobicContact CE1-CE 4.04Å; F150-M381 HydrophobicContact CE2-CB 3.97Å; F150-M381 HydrophobicContact CE2-CE 3.74Å; F150-M381 HydrophobicContact CG-CE 4.15Å; F150-M381 HydrophobicContact CZ-CE 3.8Å
151	F	82.9	Confident	80.8	Confident	149 Å²	149	62.7 Å²	62.7	65%	0.654	34%	0.338	S	S	*	.	H	α-helix	trans	-70.5	-36.7	174.8	-65	-81.6	0	0	0	112.5	A147 A148 P149	A147-F151 WeakPolarHBondContact O-CD2 3.47Å; A147-F151 WeakPolarHBondContact O-CE2 3.35Å; A148-F151 PolarHBondContact O-N 3.45Å; A148-F151 VanDerWaalsContact O-N 3.14Å; P149-F151 PolarHBondContact O-N 3.41Å; P149-F151 VanDerWaalsContact O-N 3.16Å
152	V	81.5	Confident	79.4	Confident	47 Å²	47	64.5 Å²	64.5	29%	0.285	35%	0.35	S	S	.	.	H	α-helix	trans	-68	-47.6	176.2	-178.4	0	0	0	0	110.2	P149 F154 L155 V360 V364	P149-V152 WeakPolarHBondContact O-CA 3.45Å; P149-V152 WeakPolarHBondContact O-CB 3.43Å; P149-V152 PolarHBondContact O-N 3.24Å; V152-F154 PolarHBondContact O-N 3.34Å; V152-L155 WeakPolarHBondContact O-CB 3.28Å; V152-L155 PolarHBondContact O-N 2.82Å; V152-V360 HydrophobicContact CB-CG1 4.39Å; V152-V360 HydrophobicContact CG1-CG1 4.25Å; V152-V360 HydrophobicContact CG2-CG1 3.89Å; V152-V364 HydrophobicContact CG1-CG2 4.2Å
153	L	82.2	Confident	78.2	Confident	2 Å²	2	69.6 Å²	69.6	1%	0.01	38%	0.383	C	S	.	.	H	α-helix	trans	-59.8	-31	177.4	-66	178.2	0	0	0	113	P149 L155 I156 V364 F367 K377 M381	P149-L153 WeakPolarHBondContact O-CG 3.15Å; P149-L153 PolarHBondContact O-N 3.19Å; L153-L155 PolarHBondContact O-N 2.7Å; L153-I156 HydrophobicContact CD2-CD1 3.87Å; L153-I156 PolarHBondContact O-N 3.4Å; L153-V364 HydrophobicContact CD2-CG2 4.17Å; L153-F367 HydrophobicContact CD1-CB 4.34Å; L153-F367 HydrophobicContact CD1-CD2 4.34Å; L153-F367 HydrophobicContact CD2-CB 3.56Å; L153-F367 HydrophobicContact CD2-CD1 4.05Å; L153-F367 HydrophobicContact CD2-CD2 4.08Å; L153-F367 HydrophobicContact CD2-CG 3.63Å; L153-K377 VanDerWaalsContact O-CE 3.27Å; L153-K377 WeakPolarHBondContact O-CE 3.41Å; L153-K377 PolarHBondContact O-NZ 2.89Å; L153-M381 HydrophobicContact CB-CE 4.07Å; L153-M381 HydrophobicContact CB-CG 4.31Å; L153-M381 HydrophobicContact CD1-CG 4.42Å
154	F	80.8	Confident	77.1	Confident	145 Å²	145	73.7 Å²	73.7	64%	0.636	39%	0.39	S	S	*	.	H	α-helix	trans	-59.5	-37.6	174.2	-169.3	-96.9	0	0	0	112	F150 V152 I156 K377 M381	F150-F154 PolarHBondContact O-N 3.17Å; F150-F154 VanDerWaalsContact O-N 3.14Å; V152-F154 PolarHBondContact O-N 3.34Å; F154-I156 VanDerWaalsContact C-N 3.32Å; F154-I156 PolarHBondContact O-N 3.45Å; F154-K377 PolarHBondContact O-NZ 3.49Å; F154-M381 HydrophobicContact CB-CE 4.4Å
155	L	78.8	Confident	76.4	Confident	140 Å²	140	71 Å²	71	73%	0.733	38%	0.375	S	S	*	.	H	α-helix	trans	-73.3	-17.4	-178.3	-58.3	174	0	0	0	114	V152 L153 P157	V152-L155 WeakPolarHBondContact O-CB 3.28Å; V152-L155 PolarHBondContact O-N 2.82Å; L153-L155 PolarHBondContact O-N 2.7Å; L155-P157 WeakPolarHBondContact O-CD 3.38Å
156	I	75.9	Confident	76	Confident	17 Å²	17	79.7 Å²	79.7	9%	0.087	41%	0.408	C	S	.	.	S	Bend	trans	-80.3	120	-175.2	-43.1	-177.9	0	0	0	110.7	L153 F154 V158 L172 V364 K377	L153-I156 HydrophobicContact CD2-CD1 3.87Å; L153-I156 PolarHBondContact O-N 3.4Å; F154-I156 VanDerWaalsContact C-N 3.32Å; F154-I156 PolarHBondContact O-N 3.45Å; I156-V158 HydrophobicContact CB-CG2 4.16Å; I156-V158 HydrophobicContact CG2-CG2 3.5Å; I156-V158 VanDerWaalsContact CG2-CG2 3.5Å; I156-V158 PolarHBondContact O-N 2.98Å; I156-L172 HydrophobicContact CG2-CD1 4.49Å; I156-V364 HydrophobicContact CD1-CG1 4.4Å; I156-V364 HydrophobicContact CD1-CG2 4.13Å; I156-K377 PolarHBondContact O-NZ 3.4Å
157	P	70	Confident	75.7	Confident	106 Å²	106	81 Å²	81	69%	0.688	42%	0.417	S	S	*	.			trans	-84.6	71	-170.6	34.4	-36.7	0	0	0	113.1	L155	L155-P157 WeakPolarHBondContact O-CD 3.38Å
158	V	67.7	Low	75.6	Confident	10 Å²	10	81.6 Å²	81.6	6%	0.061	42%	0.415	C	S	.	.			trans	-97.3	13.6	-166.5	161.2	0	0	0	0	115	I156 H165 F367 V371 K377	I156-V158 HydrophobicContact CB-CG2 4.16Å; I156-V158 HydrophobicContact CG2-CG2 3.5Å; I156-V158 VanDerWaalsContact CG2-CG2 3.5Å; I156-V158 PolarHBondContact O-N 2.98Å; V158-H165 VanDerWaalsContact CA-NE2 3.32Å; V158-H165 WeakPolarHBondContact CA-NE2 3.46Å; V158-H165 WeakPolarHBondContact CB-NE2 3.22Å; V158-H165 WeakPolarHBondContact CG1-NE2 3.39Å; V158-H165 WeakPolarHBondContact CG2-NE2 3.44Å; V158-H165 PolarHBondContact O-CE1 3.13Å; V158-F367 HydrophobicContact CB-CE1 3.96Å; V158-F367 HydrophobicContact CB-CZ 3.96Å; V158-F367 HydrophobicContact CG1-CE1 3.66Å; V158-F367 HydrophobicContact CG1-CZ 3.58Å; V158-F367 HydrophobicContact CG2-CE1 3.66Å; V158-F367 HydrophobicContact CG2-CZ 4.17Å; V158-V371 HydrophobicContact CG1-CG1 4.01Å; V158-V371 HydrophobicContact CG1-CG2 3.98Å; V158-K377 HydrophobicContact CB-CD 4.49Å; V158-K377 HydrophobicContact CG1-CB 4.49Å
159	E	62.2	Low	75.7	Confident	142 Å²	142	81.1 Å²	81.1	66%	0.664	41%	0.409	S	S	*	.			trans	-99.3	18.7	-166.5	-59.4	-168.9	148.3	0	0	115.4	K377	E159-K377 HydrophobicContact CG-CB 4.17Å; E159-K377 HydrophobicContact CG-CD 3.88Å
160	S	53.3	Low	76.1	Confident	72 Å²	72	82.5 Å²	82.5	50%	0.503	42%	0.416	S	S	.	.			trans	-129.4	139.2	-178	-176	0	0	0	0	114	S162 H165	S160-S162 PolarHBondContact O-N 2.82Å; S160-S162 PolarHBondContact OG-N 2.83Å; S160-H165 WeakPolarHBondContact O-CB 3.31Å; S160-H165 PolarHBondContact O-ND1 2.95Å
161	N	58.3	Low	76.4	Confident	162 Å²	162	78.9 Å²	78.9	87%	0.866	40%	0.4	S	S	*	.			trans	-75.3	22.7	173.6	-77.4	-56.3	0	0	0	113.7
162	S	66.9	Low	76.7	Confident	46 Å²	46	72.6 Å²	72.6	32%	0.322	37%	0.373	S	S	.	.			trans	-69.2	145.5	179.4	176.3	0	0	0	0	112	S160 R164 H165	S160-S162 PolarHBondContact O-N 2.82Å; S160-S162 PolarHBondContact OG-N 2.83Å; S162-R164 PolarHBondContact O-N 3.35Å; S162-R164 PolarHBondContact OG-N 2.85Å; S162-H165 WeakPolarHBondContact O-CB 3.5Å; S162-H165 PolarHBondContact O-N 3.27Å
163	P	69.4	Low	77.2	Confident	108 Å²	108	70.6 Å²	70.6	70%	0.701	36%	0.361	S	S	*	.	H	α-helix	trans	-51.7	-38.9	171.9	-27.5	35.5	0	0	0	113.4	H165 R166 S167	P163-H165 PolarHBondContact O-N 3.45Å; P163-R166 WeakPolarHBondContact O-CB 3.35Å; P163-R166 PolarHBondContact O-N 2.88Å; P163-S167 PolarHBondContact O-N 3.45Å
164	R	73	Confident	77.7	Confident	167 Å²	167	70.5 Å²	70.5	63%	0.63	36%	0.36	S	S	*	.	H	α-helix	trans	-55.4	-35.6	175.9	-176.9	176.1	-177.3	152	4.8	112.6	S162 L168	S162-R164 PolarHBondContact O-N 3.35Å; S162-R164 PolarHBondContact OG-N 2.85Å; R164-L168 PolarHBondContact O-N 2.81Å; R164-L168 VanDerWaalsContact O-N 3.08Å
165	H	78.3	Confident	78.2	Confident	29 Å²	29	64.4 Å²	64.4	13%	0.134	33%	0.333	C	S	.	.	H	α-helix	trans	-73.6	-31.7	-179.1	-174.4	-135.8	0	0	0	112	V158 S160 S162 P163 L169	V158-H165 VanDerWaalsContact CA-NE2 3.32Å; V158-H165 WeakPolarHBondContact CA-NE2 3.46Å; V158-H165 WeakPolarHBondContact CB-NE2 3.22Å; V158-H165 WeakPolarHBondContact CG1-NE2 3.39Å; V158-H165 WeakPolarHBondContact CG2-NE2 3.44Å; V158-H165 PolarHBondContact O-CE1 3.13Å; S160-H165 WeakPolarHBondContact O-CB 3.31Å; S160-H165 PolarHBondContact O-ND1 2.95Å; S162-H165 WeakPolarHBondContact O-CB 3.5Å; S162-H165 PolarHBondContact O-N 3.27Å; P163-H165 PolarHBondContact O-N 3.45Å; H165-L169 WeakPolarHBondContact O-CB 3.29Å; H165-L169 PolarHBondContact O-N 3.48Å
166	R	83.2	Confident	78.8	Confident	183 Å²	183	57.9 Å²	57.9	69%	0.691	30%	0.3	S	S	*	.	H	α-helix	trans	-66.2	-45.9	172.4	-63.7	-175.5	-178.3	175	1.3	111.9	P163 L169 Q170	P163-R166 WeakPolarHBondContact O-CB 3.35Å; P163-R166 PolarHBondContact O-N 2.88Å; R166-L169 PolarHBondContact O-N 3.14Å; R166-Q170 WeakPolarHBondContact O-CG 3.39Å; R166-Q170 PolarHBondContact O-N 3.47Å
167	S	86.2	Confident	79.7	Confident	37 Å²	37	57.1 Å²	57.1	26%	0.259	30%	0.296	S	S	.	.	H	α-helix	trans	-58.7	-47.9	176.1	162.5	0	0	0	0	111.6	P163 L169 Q170 I171 Q447	P163-S167 PolarHBondContact O-N 3.45Å; S167-L169 VanDerWaalsContact C-N 3.34Å; S167-L169 PolarHBondContact O-N 2.86Å; S167-Q170 PolarHBondContact O-N 3.44Å; S167-I171 WeakPolarHBondContact O-CG1 3.23Å; S167-I171 PolarHBondContact O-N 3.5Å; S167-I171 VanDerWaalsContact O-N 3.09Å; S167-Q447 PolarHBondContact O-NE2 3.19Å; S167-Q447 PolarHBondContact OG-OE1 3.33Å
168	L	85.9	Confident	80.8	Confident	46 Å²	46	52 Å²	52	24%	0.241	26%	0.263	C	S	.	.	H	α-helix	trans	-60.6	-42.5	175	-179.9	64.3	0	0	0	112.1	V25 R164 Q170 I171 L172	V25-L168 HydrophobicContact CG1-CD1 4.3Å; R164-L168 PolarHBondContact O-N 2.81Å; R164-L168 VanDerWaalsContact O-N 3.08Å; L168-Q170 PolarHBondContact O-N 3.08Å; L168-I171 PolarHBondContact O-N 2.85Å; L168-L172 HydrophobicContact CD1-CD1 4.41Å; L168-L172 HydrophobicContact CD1-CG 4.3Å; L168-L172 HydrophobicContact CG-CD1 4.07Å; L168-L172 HydrophobicContact CG-CG 4.38Å; L168-L172 WeakPolarHBondContact O-CG 3.42Å; L168-L172 PolarHBondContact O-N 3.08Å
169	L	87.3	Confident	82	Confident	12 Å²	12	51.8 Å²	51.8	6%	0.063	26%	0.263	C	S	.	.	H	α-helix	trans	-62.9	-40.6	179.7	-171.6	66.8	0	0	0	111.8	H165 R166 S167 L172 L173 A368 V371 Q372	H165-L169 WeakPolarHBondContact O-CB 3.29Å; H165-L169 PolarHBondContact O-N 3.48Å; R166-L169 PolarHBondContact O-N 3.14Å; S167-L169 VanDerWaalsContact C-N 3.34Å; S167-L169 PolarHBondContact O-N 2.86Å; L169-L172 PolarHBondContact O-N 2.92Å; L169-L173 WeakPolarHBondContact O-CB 3.4Å; L169-L173 PolarHBondContact O-N 3.45Å; L169-A368 HydrophobicContact CD1-CB 3.82Å; L169-V371 HydrophobicContact CD1-CB 4.33Å; L169-V371 HydrophobicContact CD1-CG1 4.2Å; L169-V371 HydrophobicContact CD2-CG1 4.33Å; L169-Q372 HydrophobicContact CD2-CB 4.1Å
170	Q	89.9	Confident	83.5	Confident	31 Å²	31	45.1 Å²	45.1	15%	0.145	23%	0.232	C	C	.	.	H	α-helix	trans	-67.1	-37.5	174.9	-63.3	-65.7	-10.6	0	0	112.4	R166 S167 L168 L173 S174 L439 E451	R166-Q170 WeakPolarHBondContact O-CG 3.39Å; R166-Q170 PolarHBondContact O-N 3.47Å; S167-Q170 PolarHBondContact O-N 3.44Å; L168-Q170 PolarHBondContact O-N 3.08Å; Q170-L173 PolarHBondContact O-N 3.01Å; Q170-S174 WeakPolarHBondContact O-CB 3.08Å; Q170-S174 PolarHBondContact O-N 3.34Å; Q170-L439 HydrophobicContact CB-CD2 4.48Å; Q170-L439 WeakPolarHBondContact O-CD2 3.3Å; Q170-E451 HydrophobicContact CB-CG 4.18Å; Q170-E451 WeakPolarHBondContact CB-OE1 3.32Å
171	I	90.6	Very high	85.5	Confident	6 Å²	6	43.1 Å²	43.1	3%	0.031	22%	0.215	C	C	.	.	H	α-helix	trans	-66.8	-42	174.7	-66.7	159.1	0	0	0	111.4	V25 S167 L168 L173 S174 F175 L450 E451	V25-I171 HydrophobicContact CG1-CD1 4.04Å; V25-I171 HydrophobicContact CG2-CD1 3.99Å; S167-I171 WeakPolarHBondContact O-CG1 3.23Å; S167-I171 PolarHBondContact O-N 3.5Å; S167-I171 VanDerWaalsContact O-N 3.09Å; L168-I171 PolarHBondContact O-N 2.85Å; I171-L173 VanDerWaalsContact C-N 3.32Å; I171-S174 PolarHBondContact O-N 2.85Å; I171-S174 PolarHBondContact O-OG 3.41Å; I171-F175 WeakPolarHBondContact O-CB 3.32Å; I171-F175 PolarHBondContact O-N 3.28Å; I171-L450 HydrophobicContact CD1-CB 4.06Å; I171-L450 HydrophobicContact CD1-CD1 4.35Å; I171-L450 HydrophobicContact CG1-CB 4.16Å; I171-E451 HydrophobicContact CG1-CG 4.46Å
172	L	89.5	Confident	87.2	Confident	17 Å²	17	35.5 Å²	35.5	9%	0.089	18%	0.175	C	C	.	.	H	α-helix	trans	-65	-38.2	174	-70.4	173.5	0	0	0	111.5	W18 I156 L168 L169 F175 A176 V364 A368	W18-L172 HydrophobicContact CH2-CD2 4.42Å; I156-L172 HydrophobicContact CG2-CD1 4.49Å; L168-L172 HydrophobicContact CD1-CD1 4.41Å; L168-L172 HydrophobicContact CD1-CG 4.3Å; L168-L172 HydrophobicContact CG-CD1 4.07Å; L168-L172 HydrophobicContact CG-CG 4.38Å; L168-L172 WeakPolarHBondContact O-CG 3.42Å; L168-L172 PolarHBondContact O-N 3.08Å; L169-L172 PolarHBondContact O-N 2.92Å; L172-F175 PolarHBondContact O-N 3.14Å; L172-A176 WeakPolarHBondContact O-CB 3.4Å; L172-A176 PolarHBondContact O-N 3.38Å; L172-V364 HydrophobicContact CD2-CG1 3.87Å; L172-A368 HydrophobicContact CB-CB 3.8Å
173	L	91.1	Very high	88.4	Confident	4 Å²	4	33.3 Å²	33.3	2%	0.021	16%	0.16	C	C	.	.	H	α-helix	trans	-68.3	-35.8	176.9	-178.4	63.9	0	0	0	112.2	L169 Q170 I171 A176 S177 I369 Q372 V435 E438 L439	L169-L173 WeakPolarHBondContact O-CB 3.4Å; L169-L173 PolarHBondContact O-N 3.45Å; Q170-L173 PolarHBondContact O-N 3.01Å; I171-L173 VanDerWaalsContact C-N 3.32Å; L173-A176 WeakPolarHBondContact O-CB 3.39Å; L173-A176 PolarHBondContact O-N 3.02Å; L173-S177 PolarHBondContact O-N 2.95Å; L173-I369 HydrophobicContact CD1-CB 4.48Å; L173-I369 HydrophobicContact CD1-CD1 4.32Å; L173-I369 HydrophobicContact CD1-CG1 3.4Å; L173-I369 VanDerWaalsContact CD1-CG1 3.4Å; L173-Q372 HydrophobicContact CD2-CG 4.42Å; L173-V435 HydrophobicContact CD1-CB 4.17Å; L173-V435 HydrophobicContact CD1-CG1 3.47Å; L173-V435 VanDerWaalsContact CD1-CG1 3.47Å; L173-V435 HydrophobicContact CD1-CG2 3.88Å; L173-V435 HydrophobicContact CD2-CG1 4.47Å; L173-V435 HydrophobicContact CG-CG1 3.64Å; L173-V435 WeakPolarHBondContact O-CG1 3.14Å; L173-E438 HydrophobicContact CD2-CB 3.93Å; L173-E438 HydrophobicContact CD2-CG 3.65Å; L173-L439 HydrophobicContact CB-CD2 4.28Å; L173-L439 HydrophobicContact CD2-CD2 4.16Å; L173-L439 HydrophobicContact CG-CD2 4.12Å
174	S	93.2	Very high	89.5	Confident	0 Å²	0	28.2 Å²	28.2	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-70	-43	173.9	81.6	0	0	0	0	111.4	Q170 I171 A176 S177 G178 E451 G454 L455	Q170-S174 WeakPolarHBondContact O-CB 3.08Å; Q170-S174 PolarHBondContact O-N 3.34Å; I171-S174 PolarHBondContact O-N 2.85Å; I171-S174 PolarHBondContact O-OG 3.41Å; S174-A176 VanDerWaalsContact C-N 3.33Å; S174-A176 PolarHBondContact O-N 3.25Å; S174-S177 WeakPolarHBondContact O-CB 3.33Å; S174-S177 PolarHBondContact O-N 2.82Å; S174-G178 PolarHBondContact O-N 3.23Å; S174-E451 WeakPolarHBondContact CB-O 3.41Å; S174-E451 WeakPolarHBondContact OG-CA 3.47Å; S174-E451 PolarHBondContact OG-O 3.13Å; S174-G454 WeakPolarHBondContact OG-CA 3.45Å; S174-L455 WeakPolarHBondContact O-CA 3.28Å; S174-L455 WeakPolarHBondContact O-CB 3.43Å; S174-L455 PolarHBondContact OG-N 2.99Å
175	F	92.4	Very high	90.5	Very high	17 Å²	17	25.7 Å²	25.7	8%	0.075	12%	0.12	C	C	.	.	H	α-helix	trans	-57.1	-43.7	170.2	179.3	-92.9	0	0	0	112.1	I171 L172 S177 G178 G179 P361 G454 M461	I171-F175 WeakPolarHBondContact O-CB 3.32Å; I171-F175 PolarHBondContact O-N 3.28Å; L172-F175 PolarHBondContact O-N 3.14Å; F175-S177 PolarHBondContact O-N 2.74Å; F175-G178 PolarHBondContact O-N 3.11Å; F175-G179 PolarHBondContact O-N 3.48Å; F175-P361 HydrophobicContact CE1-CB 4.11Å; F175-P361 HydrophobicContact CZ-CB 4.27Å; F175-G454 VanDerWaalsContact CA-O 3.31Å; F175-G454 WeakPolarHBondContact CA-O 3.45Å; F175-M461 HydrophobicContact CE2-SD 4.36Å; F175-M461 HydrophobicContact CZ-SD 3.64Å
176	A	90.4	Very high	91.1	Very high	4 Å²	4	27.6 Å²	27.6	3%	0.033	13%	0.131	C	C	.	.	H	α-helix	trans	-56.6	-48.4	173.4	0	0	0	0	0	112	L172 L173 S174 G178 G179 L180 I369	L172-A176 WeakPolarHBondContact O-CB 3.4Å; L172-A176 PolarHBondContact O-N 3.38Å; L173-A176 WeakPolarHBondContact O-CB 3.39Å; L173-A176 PolarHBondContact O-N 3.02Å; S174-A176 VanDerWaalsContact C-N 3.33Å; S174-A176 PolarHBondContact O-N 3.25Å; A176-G178 VanDerWaalsContact C-N 3.29Å; A176-G178 PolarHBondContact O-N 2.89Å; A176-G179 PolarHBondContact O-N 3.33Å; A176-L180 WeakPolarHBondContact O-CB 3.35Å; A176-L180 WeakPolarHBondContact O-CG 3.24Å; A176-L180 PolarHBondContact O-N 3.28Å; A176-I369 HydrophobicContact CB-CD1 4.1Å
177	S	93.9	Very high	91.2	Very high	0 Å²	0	20.6 Å²	20.6	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-59.2	-41.2	176.9	-161.5	0	0	0	0	112.1	L173 S174 F175 L181 L436	L173-S177 PolarHBondContact O-N 2.95Å; S174-S177 WeakPolarHBondContact O-CB 3.33Å; S174-S177 PolarHBondContact O-N 2.82Å; F175-S177 PolarHBondContact O-N 2.74Å; S177-L181 WeakPolarHBondContact O-CB 3.43Å; S177-L181 VanDerWaalsContact O-CG 3.25Å; S177-L181 WeakPolarHBondContact O-CG 3.3Å; S177-L181 PolarHBondContact O-N 3.43Å; S177-L436 WeakPolarHBondContact OG-CD1 3.31Å
178	G	94.3	Very high	91.3	Very high	0 Å²	0	18.9 Å²	18.9	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-65.5	-41.5	175.7	0	0	0	0	0	113.3	S174 F175 A176 G182 L455 V459	S174-G178 PolarHBondContact O-N 3.23Å; F175-G178 PolarHBondContact O-N 3.11Å; A176-G178 VanDerWaalsContact C-N 3.29Å; A176-G178 PolarHBondContact O-N 2.89Å; G178-G182 WeakPolarHBondContact O-CA 3.46Å; G178-G182 PolarHBondContact O-N 3.29Å; G178-L455 WeakPolarHBondContact CA-O 3.41Å; G178-V459 WeakPolarHBondContact O-CG2 3.34Å; G178-V459 PolarHBondContact O-N 2.78Å
179	G	92.7	Very high	91.5	Very high	5 Å²	5	18 Å²	18	5%	0.052	9%	0.089	C	C	.	.	H	α-helix	trans	-63.5	-55.3	174.8	0	0	0	0	0	112	F175 A176 L181 G182 D183 M462	F175-G179 PolarHBondContact O-N 3.48Å; A176-G179 PolarHBondContact O-N 3.33Å; G179-L181 VanDerWaalsContact C-N 3.33Å; G179-L181 PolarHBondContact O-N 3.45Å; G179-G182 CarbonylContact O-C 3.58Å; G179-G182 PolarHBondContact O-N 2.93Å; G179-G182 VanDerWaalsContact O-N 3.09Å; G179-D183 WeakPolarHBondContact O-CB 3.27Å; G179-D183 PolarHBondContact O-N 3.18Å; G179-M462 WeakPolarHBondContact O-CG 3.04Å
180	L	93.3	Very high	91.5	Very high	2 Å²	2	19.6 Å²	19.6	1%	0.01	10%	0.1	C	C	.	.	H	α-helix	trans	-57.7	-40	179.1	-68.7	170.6	0	0	0	113.2	A176 A184 I369 F427 V430 A431	A176-L180 WeakPolarHBondContact O-CB 3.35Å; A176-L180 WeakPolarHBondContact O-CG 3.24Å; A176-L180 PolarHBondContact O-N 3.28Å; L180-A184 WeakPolarHBondContact O-CB 3.45Å; L180-A184 PolarHBondContact O-N 2.89Å; L180-A184 VanDerWaalsContact O-N 3.14Å; L180-I369 HydrophobicContact CD1-CD1 4.13Å; L180-F427 HydrophobicContact CB-CD2 4.5Å; L180-F427 HydrophobicContact CD2-CD1 3.98Å; L180-F427 HydrophobicContact CD2-CD2 3.67Å; L180-F427 HydrophobicContact CD2-CE1 3.91Å; L180-F427 HydrophobicContact CD2-CE2 3.62Å; L180-F427 HydrophobicContact CD2-CG 3.82Å; L180-F427 HydrophobicContact CD2-CZ 3.72Å; L180-V430 HydrophobicContact CD1-CG1 3.96Å; L180-A431 HydrophobicContact CB-CB 4.07Å; L180-A431 HydrophobicContact CD1-CB 4.49Å
181	L	95.3	Very high	91.1	Very high	30 Å²	30	21.8 Å²	21.8	16%	0.157	11%	0.11	C	C	.	.	H	α-helix	trans	-73.1	-39.8	174.5	-70.2	171.2	0	0	0	112	S177 G179 F185 I428 A431 T432 L436	S177-L181 WeakPolarHBondContact O-CB 3.43Å; S177-L181 VanDerWaalsContact O-CG 3.25Å; S177-L181 WeakPolarHBondContact O-CG 3.3Å; S177-L181 PolarHBondContact O-N 3.43Å; G179-L181 VanDerWaalsContact C-N 3.33Å; G179-L181 PolarHBondContact O-N 3.45Å; L181-F185 HydrophobicContact CD2-CD2 4.46Å; L181-F185 HydrophobicContact CD2-CE2 4.11Å; L181-F185 WeakPolarHBondContact O-CB 3.46Å; L181-F185 WeakPolarHBondContact O-CD2 3.47Å; L181-F185 PolarHBondContact O-N 3.35Å; L181-I428 HydrophobicContact CD2-CG1 4.38Å; L181-A431 HydrophobicContact CD1-CB 4.28Å; L181-A431 HydrophobicContact CD2-CB 3.9Å; L181-A431 HydrophobicContact CG-CB 3.69Å; L181-T432 HydrophobicContact CD2-CG2 4.15Å; L181-L436 HydrophobicContact CD1-CD1 4.07Å
182	G	93.8	Very high	90.7	Very high	2 Å²	2	22.5 Å²	22.5	2%	0.021	12%	0.117	C	C	.	.	H	α-helix	trans	-59	-48.7	175.7	0	0	0	0	0	111.4	G178 G179 L186	G178-G182 WeakPolarHBondContact O-CA 3.46Å; G178-G182 PolarHBondContact O-N 3.29Å; G179-G182 CarbonylContact O-C 3.58Å; G179-G182 PolarHBondContact O-N 2.93Å; G179-G182 VanDerWaalsContact O-N 3.09Å; G182-L186 WeakPolarHBondContact O-CA 3.31Å; G182-L186 WeakPolarHBondContact O-CB 3.44Å; G182-L186 VanDerWaalsContact O-CG 3.24Å; G182-L186 WeakPolarHBondContact O-CG 3.37Å; G182-L186 PolarHBondContact O-N 3.34Å
183	D	91.6	Very high	90.5	Very high	0 Å²	0	24.7 Å²	24.7	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-61.2	-53	177	176.2	59.6	0	0	0	112.3	G179 F185 H187 L188 H329 F427 M462	G179-D183 WeakPolarHBondContact O-CB 3.27Å; G179-D183 PolarHBondContact O-N 3.18Å; D183-F185 VanDerWaalsContact C-N 3.3Å; D183-F185 PolarHBondContact O-N 3.03Å; D183-H187 WeakPolarHBondContact O-CA 3.37Å; D183-H187 WeakPolarHBondContact O-CB 3.49Å; D183-H187 PolarHBondContact O-N 2.87Å; D183-H187 WeakPolarHBondContact OD1-CB 3.25Å; D183-H187 IonicContact OD1-CD2 3.32Å; D183-H187 IonicContact OD1-CG 2.77Å; D183-L188 PolarHBondContact O-N 3.05Å; D183-L188 WeakPolarHBondContact OD2-CD1 3.47Å; D183-L188 VanDerWaalsContact OD2-CG 3.32Å; D183-L188 WeakPolarHBondContact OD2-CG 3.39Å; D183-H329 IonicContact OD1-CE1 3.88Å; D183-H329 IonicContact OD2-CE1 3.99Å; D183-H329 PolarHBondContact OD2-CE1 3.37Å; D183-H329 IonicContact OD2-ND1 3.14Å; D183-H329 PolarHBondContact OD2-ND1 3.47Å; D183-F427 HydrophobicContact CB-CD2 4.23Å; D183-F427 HydrophobicContact CB-CE2 4.33Å; D183-F427 WeakPolarHBondContact OD2-CD2 3.48Å; D183-F427 WeakPolarHBondContact OD2-CE2 3.28Å; D183-M462 HydrophobicContact CB-CE 3.81Å; D183-M462 HydrophobicContact CB-SD 4.42Å
184	A	93	Very high	89.7	Confident	0 Å²	0	29.9 Å²	29.9	0%	0	15%	0.153	C	C	.	.	I	π-helix	trans	-55.9	-43.6	179.8	0	0	0	0	0	112.7	L180 I189 A424 F427 I428	L180-A184 WeakPolarHBondContact O-CB 3.45Å; L180-A184 PolarHBondContact O-N 2.89Å; L180-A184 VanDerWaalsContact O-N 3.14Å; A184-I189 VanDerWaalsContact O-CB 3.27Å; A184-I189 WeakPolarHBondContact O-CB 3.41Å; A184-I189 VanDerWaalsContact O-CD1 3.32Å; A184-I189 WeakPolarHBondContact O-CD1 3.33Å; A184-I189 WeakPolarHBondContact O-CG1 3.46Å; A184-I189 PolarHBondContact O-N 3.46Å; A184-I189 VanDerWaalsContact O-N 3.09Å; A184-A424 HydrophobicContact CB-CB 4Å; A184-F427 HydrophobicContact CB-CB 4.08Å; A184-I428 HydrophobicContact CB-CD1 4.15Å; A184-I428 HydrophobicContact CB-CG1 3.76Å
185	F	94.6	Very high	88	Confident	115 Å²	115	34 Å²	34	50%	0.504	18%	0.18	S	C	.	.	I	π-helix	trans	-92.1	-23.5	-174.8	-76.8	-70.1	0	0	0	115.6	L181 D183 I189 P190 I428	L181-F185 HydrophobicContact CD2-CD2 4.46Å; L181-F185 HydrophobicContact CD2-CE2 4.11Å; L181-F185 WeakPolarHBondContact O-CB 3.46Å; L181-F185 WeakPolarHBondContact O-CD2 3.47Å; L181-F185 PolarHBondContact O-N 3.35Å; D183-F185 VanDerWaalsContact C-N 3.3Å; D183-F185 PolarHBondContact O-N 3.03Å; F185-I189 HydrophobicContact CD1-CD1 4.08Å; F185-I189 HydrophobicContact CE1-CD1 4.25Å; F185-P190 WeakPolarHBondContact O-CD 3.44Å; F185-P190 WeakPolarHBondContact O-CG 3.33Å; F185-I428 HydrophobicContact CE1-CD1 4.21Å; F185-I428 HydrophobicContact CE2-CD1 3.86Å; F185-I428 HydrophobicContact CE2-CG1 3.86Å; F185-I428 HydrophobicContact CZ-CD1 3.66Å; F185-I428 HydrophobicContact CZ-CG1 4.16Å
186	L	91.1	Very high	86.1	Confident	69 Å²	69	37.1 Å²	37.1	36%	0.361	19%	0.194	S	C	.	.	I	π-helix	trans	-111.1	-22	-174	-51.9	174.3	0	0	0	113.5	G182 M462 V463	G182-L186 WeakPolarHBondContact O-CA 3.31Å; G182-L186 WeakPolarHBondContact O-CB 3.44Å; G182-L186 VanDerWaalsContact O-CG 3.24Å; G182-L186 WeakPolarHBondContact O-CG 3.37Å; G182-L186 PolarHBondContact O-N 3.34Å; L186-M462 HydrophobicContact CD1-CB 4.41Å; L186-V463 HydrophobicContact CD1-CB 4.43Å; L186-V463 HydrophobicContact CD1-CG2 3.44Å; L186-V463 VanDerWaalsContact CD1-CG2 3.44Å
187	H	85.4	Confident	83.6	Confident	35 Å²	35	42.1 Å²	42.1	16%	0.162	23%	0.229	C	C	.	.	I	π-helix	trans	-113.6	-68.3	178.9	-172.4	75.6	0	0	0	110.7	D183 I189 P190 H191 H358 E469	D183-H187 WeakPolarHBondContact O-CA 3.37Å; D183-H187 WeakPolarHBondContact O-CB 3.49Å; D183-H187 PolarHBondContact O-N 2.87Å; D183-H187 WeakPolarHBondContact OD1-CB 3.25Å; D183-H187 IonicContact OD1-CD2 3.32Å; D183-H187 IonicContact OD1-CG 2.77Å; H187-I189 PolarHBondContact O-N 3.38Å; H187-P190 WeakPolarHBondContact O-CD 3.39Å; H187-H191 VanDerWaalsContact O-CB 3.24Å; H187-H191 WeakPolarHBondContact O-CB 3.34Å; H187-H191 PolarHBondContact O-N 3.19Å; H187-H358 AromaticContact NE2-CE1 3.96Å; H187-E469 VanDerWaalsContact CE1-CD 3.44Å; H187-E469 IonicContact CE1-OE1 3.71Å; H187-E469 PolarHBondContact CE1-OE1 3.4Å; H187-E469 IonicContact CE1-OE2 3.79Å; H187-E469 PolarHBondContact CE1-OE2 2.92Å; H187-E469 VanDerWaalsContact CE1-OE2 3.32Å; H187-E469 IonicContact CG-OE2 3.61Å; H187-E469 VanDerWaalsContact ND1-CD 3.31Å; H187-E469 IonicContact ND1-OE1 3.76Å; H187-E469 PolarHBondContact ND1-OE1 3.38Å; H187-E469 IonicContact ND1-OE2 3.21Å; H187-E469 PolarHBondContact ND1-OE2 3.47Å
188	L	88.1	Confident	81.2	Confident	2 Å²	2	49.6 Å²	49.6	1%	0.01	26%	0.263	C	S	.	.	I	π-helix	trans	-63.2	-48.7	-171.3	-61.6	-179.5	0	0	0	114.5	D183 A192 L420 T423 A424 F427	D183-L188 PolarHBondContact O-N 3.05Å; D183-L188 WeakPolarHBondContact OD2-CD1 3.47Å; D183-L188 VanDerWaalsContact OD2-CG 3.32Å; D183-L188 WeakPolarHBondContact OD2-CG 3.39Å; L188-A192 WeakPolarHBondContact O-CB 3.42Å; L188-A192 PolarHBondContact O-N 2.97Å; L188-A192 VanDerWaalsContact O-N 3.14Å; L188-L420 HydrophobicContact CD2-CD2 3.69Å; L188-T423 HydrophobicContact CD1-CG2 3.88Å; L188-A424 HydrophobicContact CB-CB 3.78Å; L188-A424 HydrophobicContact CD1-CB 3.91Å; L188-F427 HydrophobicContact CD1-CD2 4.36Å
189	I	90.5	Very high	78.4	Confident	28 Å²	28	58.7 Å²	58.7	14%	0.144	31%	0.306	C	S	.	.	H	α-helix	trans	-68.3	-48.5	-179.9	-72.8	167.8	0	0	0	111.8	A184 F185 H187 H191 A192 L193 V219 V223 A424 I428	A184-I189 VanDerWaalsContact O-CB 3.27Å; A184-I189 WeakPolarHBondContact O-CB 3.41Å; A184-I189 VanDerWaalsContact O-CD1 3.32Å; A184-I189 WeakPolarHBondContact O-CD1 3.33Å; A184-I189 WeakPolarHBondContact O-CG1 3.46Å; A184-I189 PolarHBondContact O-N 3.46Å; A184-I189 VanDerWaalsContact O-N 3.09Å; F185-I189 HydrophobicContact CD1-CD1 4.08Å; F185-I189 HydrophobicContact CE1-CD1 4.25Å; H187-I189 PolarHBondContact O-N 3.38Å; I189-H191 PolarHBondContact O-N 2.86Å; I189-A192 PolarHBondContact O-N 3.26Å; I189-L193 HydrophobicContact CG2-CD1 3.85Å; I189-L193 HydrophobicContact CG2-CG 4.47Å; I189-L193 WeakPolarHBondContact O-CG 3.38Å; I189-L193 PolarHBondContact O-N 3.47Å; I189-L193 VanDerWaalsContact O-N 3.15Å; I189-V219 HydrophobicContact CG2-CG1 4.34Å; I189-V223 HydrophobicContact CD1-CG1 4.37Å; I189-V223 HydrophobicContact CD1-CG2 3.85Å; I189-V223 HydrophobicContact CG1-CG2 3.8Å; I189-A424 HydrophobicContact CD1-CB 4.19Å; I189-A424 HydrophobicContact CG1-CB 3.8Å; I189-I428 HydrophobicContact CD1-CD1 4.22Å
190	P	87	Confident	75.8	Confident	44 Å²	44	64.9 Å²	64.9	29%	0.286	34%	0.342	S	S	.	.	H	α-helix	trans	-58.6	-44.8	175.8	-29	39.1	0	0	0	113.2	F185 H187 A192 L193 E194	F185-P190 WeakPolarHBondContact O-CD 3.44Å; F185-P190 WeakPolarHBondContact O-CG 3.33Å; H187-P190 WeakPolarHBondContact O-CD 3.39Å; P190-A192 VanDerWaalsContact C-N 3.27Å; P190-A192 PolarHBondContact O-N 2.91Å; P190-L193 WeakPolarHBondContact O-CA 3.13Å; P190-L193 WeakPolarHBondContact O-CB 3.27Å; P190-L193 PolarHBondContact O-N 3.03Å; P190-E194 PolarHBondContact O-N 3.39Å
191	H	81.2	Confident	73.3	Confident	77 Å²	77	72.8 Å²	72.8	36%	0.356	38%	0.384	S	S	.	.	H	α-helix	trans	-63.5	-34.1	179.2	-154	78.1	0	0	0	112.1	H187 I189 L193 L420	H187-H191 VanDerWaalsContact O-CB 3.24Å; H187-H191 WeakPolarHBondContact O-CB 3.34Å; H187-H191 PolarHBondContact O-N 3.19Å; I189-H191 PolarHBondContact O-N 2.86Å; H191-L193 VanDerWaalsContact C-N 3.29Å; H191-L193 PolarHBondContact O-N 3.21Å; H191-L420 HydrophobicContact CB-CD1 4.48Å
192	A	82.9	Confident	70.5	Confident	22 Å²	22	80 Å²	80	18%	0.182	42%	0.417	C	S	.	.	H	α-helix	trans	-71.1	-19.9	172.4	0	0	0	0	0	114.3	L188 I189 P190 V219 L420 P421	L188-A192 WeakPolarHBondContact O-CB 3.42Å; L188-A192 PolarHBondContact O-N 2.97Å; L188-A192 VanDerWaalsContact O-N 3.14Å; I189-A192 PolarHBondContact O-N 3.26Å; P190-A192 VanDerWaalsContact C-N 3.27Å; P190-A192 PolarHBondContact O-N 2.91Å; A192-V219 HydrophobicContact CB-CG1 4.24Å; A192-V219 HydrophobicContact CB-CG2 3.92Å; A192-V219 VanDerWaalsContact O-CG2 3.26Å; A192-V219 WeakPolarHBondContact O-CG2 3.35Å; A192-L420 HydrophobicContact CB-CB 4.27Å; A192-P421 HydrophobicContact CB-CB 4.44Å; A192-P421 HydrophobicContact CB-CG 4.14Å
193	L	85.5	Confident	68.1	Low	62 Å²	62	88.8 Å²	88.8	33%	0.325	46%	0.457	S	S	.	.	H	α-helix	trans	-91.6	-14.6	179.6	-72.8	170.2	0	0	0	113.8	I189 P190 H191 P195 I216 V219	I189-L193 HydrophobicContact CG2-CD1 3.85Å; I189-L193 HydrophobicContact CG2-CG 4.47Å; I189-L193 WeakPolarHBondContact O-CG 3.38Å; I189-L193 PolarHBondContact O-N 3.47Å; I189-L193 VanDerWaalsContact O-N 3.15Å; P190-L193 WeakPolarHBondContact O-CA 3.13Å; P190-L193 WeakPolarHBondContact O-CB 3.27Å; P190-L193 PolarHBondContact O-N 3.03Å; H191-L193 VanDerWaalsContact C-N 3.29Å; H191-L193 PolarHBondContact O-N 3.21Å; L193-P195 WeakPolarHBondContact O-CD 3.03Å; L193-I216 HydrophobicContact CD2-CB 4.31Å; L193-I216 HydrophobicContact CD2-CG1 3.94Å; L193-V219 HydrophobicContact CD2-CB 3.86Å; L193-V219 HydrophobicContact CD2-CG1 3.96Å; L193-V219 HydrophobicContact CD2-CG2 3.86Å; L193-V219 HydrophobicContact CG-CB 4.45Å; L193-V219 HydrophobicContact CG-CG1 4.06Å; L193-V219 HydrophobicContact CG-CG2 4.31Å
194	E	73.1	Confident	65.5	Low	113 Å²	113	94.5 Å²	94.5	53%	0.528	49%	0.494	S	S	.	.			trans	-93.4	97.9	-179.5	-72	-166.1	-175	0	0	112.4	P190 H196	P190-E194 PolarHBondContact O-N 3.39Å; E194-H196 PolarHBondContact O-N 3.47Å; E194-H196 IonicContact OE2-CE1 3.51Å; E194-H196 PolarHBondContact OE2-CE1 2.86Å
195	P	57.1	Low	63	Low	88 Å²	88	97.8 Å²	97.8	57%	0.571	53%	0.528	S	S	*	.			trans	-71.3	99.6	167.5	30.1	-34.7	0	0	0	109.3	L193 S197	L193-P195 WeakPolarHBondContact O-CD 3.03Å; P195-S197 VanDerWaalsContact C-N 3.33Å; P195-S197 PolarHBondContact O-N 2.85Å
196	H	53.3	Low	60.7	Low	82 Å²	82	101.2 Å²	101.2	38%	0.38	55%	0.546	S	S	.	.			trans	-63.4	93.3	169.9	-72.1	-11.5	0	0	0	110.4	E194 H198 A411	E194-H196 PolarHBondContact O-N 3.47Å; E194-H196 IonicContact OE2-CE1 3.51Å; E194-H196 PolarHBondContact OE2-CE1 2.86Å; H196-H198 VanDerWaalsContact C-N 3.34Å; H196-H198 PolarHBondContact O-N 3.45Å; H196-A411 PolarHBondContact CD2-O 3.01Å
197	S	38.4	Very low	58.1	Low	108 Å²	108	101.5 Å²	101.5	76%	0.755	57%	0.565	S	S	*	*			trans	-71.1	82.3	-176.4	58.7	0	0	0	0	111.7	P195 H199	P195-S197 VanDerWaalsContact C-N 3.33Å; P195-S197 PolarHBondContact O-N 2.85Å; S197-H199 PolarHBondContact O-N 3.2Å
198	H	42.9	Very low	56	Low	157 Å²	157	108.4 Å²	108.4	73%	0.727	60%	0.597	S	S	*	*			trans	-65.6	120.3	166.1	-82.8	-67	0	0	0	110	H196 T200	H196-H198 VanDerWaalsContact C-N 3.34Å; H196-H198 PolarHBondContact O-N 3.45Å; H198-T200 PolarHBondContact O-N 2.85Å
199	H	35.3	Very low	53.6	Low	191 Å²	191	113 Å²	113	88%	0.884	63%	0.629	S	S	*	*			trans	-51.1	96.6	180	-67.5	-88.6	0	0	0	113.1	S197	S197-H199 PolarHBondContact O-N 3.2Å
200	T	39.5	Very low	51.2	Low	135 Å²	135	120.6 Å²	120.6	83%	0.828	66%	0.664	S	S	*	*	P	Polyproline II helix	trans	-81.6	129	153.3	46.4	0	0	0	0	108.3	H198	H198-T200 PolarHBondContact O-N 2.85Å
201	L	40.8	Very low	49.3	Very low	168 Å²	168	123.2 Å²	123.2	88%	0.88	68%	0.683	S	S	*	*	P	Polyproline II helix	trans	-61.8	151.6	-177.1	-79.1	155.3	0	0	0	111.9
202	E	35.3	Very low	47.9	Very low	182 Å²	182	123.2 Å²	123.2	85%	0.85	70%	0.704	S	S	*	*	P	Polyproline II helix	trans	-48.4	130.5	-167.8	-53.9	-174.1	154.9	0	0	115.2
203	Q	43	Very low	46.7	Very low	186 Å²	186	129.8 Å²	129.8	87%	0.869	73%	0.731	S	S	*	*			trans	-130.6	105.3	150.3	-72.2	-160.9	36.4	0	0	109.8	G205	Q203-G205 PolarHBondContact O-N 3.5Å
204	P	37.5	Very low	45.9	Very low	120 Å²	120	128.5 Å²	128.5	78%	0.779	73%	0.733	S	S	*	*			trans	-78.7	70.3	176.1	31.6	-33.8	0	0	0	111.3
205	G	41.6	Very low	46.1	Very low	69 Å²	69	126 Å²	126	71%	0.711	73%	0.726	S	S	*	*			trans	-97	117.3	176.3	0	0	0	0	0	112.3	Q203	Q203-G205 PolarHBondContact O-N 3.5Å
206	H	44.9	Very low	47.4	Very low	188 Å²	188	127 Å²	127	87%	0.87	73%	0.725	S	S	*	*			trans	-73	127.6	-176.8	-71.9	45.1	0	0	0	112.6
207	G	37.8	Very low	49	Very low	74 Å²	74	128.3 Å²	128.3	76%	0.763	74%	0.735	S	S	*	*			trans	-161.3	113.1	170.2	0	0	0	0	0	111
208	H	39.7	Very low	51.3	Low	181 Å²	181	125.7 Å²	125.7	84%	0.838	72%	0.717	S	S	*	*			trans	-79.4	155.9	-172.5	-66.2	-72.4	0	0	0	114
209	S	37.7	Very low	53.5	Low	98 Å²	98	118.6 Å²	118.6	69%	0.685	68%	0.684	S	S	*	*			trans	103.3	127.2	143.9	81.7	0	0	0	0	120.3
210	H	40.8	Very low	56.2	Low	188 Å²	188	111.4 Å²	111.4	87%	0.87	66%	0.661	S	S	*	*			trans	50.4	83.3	159.8	-47.8	-70.3	0	0	0	120.5
211	S	47	Very low	58.8	Low	98 Å²	98	109.8 Å²	109.8	69%	0.685	65%	0.647	S	S	*	*			trans	-150.9	5.7	168	61.5	0	0	0	0	119.2	Q213 G214	S211-Q213 PolarHBondContact O-N 3.18Å; S211-G214 PolarHBondContact O-N 3Å
212	G	52.6	Low	61.2	Low	77 Å²	77	106.5 Å²	106.5	79%	0.794	62%	0.623	S	S	*	*	T	Hydrogen-bonded Turn	trans	-61.9	-14.3	178.4	0	0	0	0	0	115.8
213	Q	57.9	Low	64	Low	160 Å²	160	98.6 Å²	98.6	75%	0.748	59%	0.587	S	S	*	*	T	Hydrogen-bonded Turn	trans	-102.5	-3.1	176.1	-70	174.8	-23.9	0	0	113.5	S211 I216 L217	S211-Q213 PolarHBondContact O-N 3.18Å; Q213-I216 PolarHBondContact O-N 3.36Å; Q213-L217 WeakPolarHBondContact O-CB 3.4Å; Q213-L217 PolarHBondContact O-N 2.91Å
214	G	68.4	Low	66.5	Low	36 Å²	36	94.4 Å²	94.4	37%	0.371	57%	0.57	S	S	.	*	H	α-helix	trans	-56.6	-54.9	-173.6	0	0	0	0	0	113.8	S211 L217 S218	S211-G214 PolarHBondContact O-N 3Å; G214-L217 PolarHBondContact O-N 3.28Å; G214-S218 WeakPolarHBondContact O-CB 3.11Å; G214-S218 PolarHBondContact O-N 3.44Å; G214-S218 PolarHBondContact O-OG 3.11Å
215	P	75.8	Confident	69.2	Low	59 Å²	59	90.9 Å²	90.9	38%	0.383	55%	0.548	S	S	.	.	H	α-helix	trans	-61.6	-44.9	178.6	-24.2	34.8	0	0	0	112.9	L217 S218 V219	P215-L217 PolarHBondContact O-N 3.31Å; P215-S218 PolarHBondContact O-N 3.21Å; P215-S218 PolarHBondContact O-OG 3.31Å; P215-V219 WeakPolarHBondContact O-CB 3.17Å; P215-V219 VanDerWaalsContact O-CG2 3.29Å; P215-V219 WeakPolarHBondContact O-CG2 3.49Å; P215-V219 PolarHBondContact O-N 3Å
216	I	84.8	Confident	71.6	Confident	109 Å²	109	87.6 Å²	87.6	56%	0.559	51%	0.514	S	S	*	.	H	α-helix	trans	-62.7	-44	-178.5	-61.2	163.5	0	0	0	110.8	L193 Q213 G220	L193-I216 HydrophobicContact CD2-CB 4.31Å; L193-I216 HydrophobicContact CD2-CG1 3.94Å; Q213-I216 PolarHBondContact O-N 3.36Å; I216-G220 PolarHBondContact O-N 2.81Å
217	L	86.7	Confident	74	Confident	111 Å²	111	80.9 Å²	80.9	58%	0.581	49%	0.485	S	S	*	.	H	α-helix	trans	-66.7	-42	177.1	179.9	61.5	0	0	0	111.6	Q213 G214 P215 G220 L221	Q213-L217 WeakPolarHBondContact O-CB 3.4Å; Q213-L217 PolarHBondContact O-N 2.91Å; G214-L217 PolarHBondContact O-N 3.28Å; P215-L217 PolarHBondContact O-N 3.31Å; L217-G220 PolarHBondContact O-N 3.2Å; L217-L221 HydrophobicContact CD1-CD1 4.21Å; L217-L221 HydrophobicContact CD1-CG 4.22Å; L217-L221 HydrophobicContact CG-CD1 4.05Å; L217-L221 HydrophobicContact CG-CG 4.48Å; L217-L221 WeakPolarHBondContact O-CB 3.29Å; L217-L221 VanDerWaalsContact O-CG 3.24Å; L217-L221 WeakPolarHBondContact O-CG 3.46Å; L217-L221 PolarHBondContact O-N 2.83Å
218	S	86.8	Confident	76.8	Confident	53 Å²	53	80.9 Å²	80.9	37%	0.371	47%	0.469	S	S	.	.	H	α-helix	trans	-66.1	-45.1	179.7	66.6	0	0	0	0	111.7	G214 P215 L221 W222	G214-S218 WeakPolarHBondContact O-CB 3.11Å; G214-S218 PolarHBondContact O-N 3.44Å; G214-S218 PolarHBondContact O-OG 3.11Å; P215-S218 PolarHBondContact O-N 3.21Å; P215-S218 PolarHBondContact O-OG 3.31Å; S218-L221 PolarHBondContact O-N 2.98Å; S218-W222 PolarHBondContact O-N 3.45Å
219	V	89.3	Confident	79.2	Confident	8 Å²	8	73.8 Å²	73.8	5%	0.048	44%	0.442	C	S	.	.	H	α-helix	trans	-57.3	-51	173.4	169.2	0	0	0	0	110.5	I189 A192 L193 P215 L221 W222 V223 P421	I189-V219 HydrophobicContact CG2-CG1 4.34Å; A192-V219 HydrophobicContact CB-CG1 4.24Å; A192-V219 HydrophobicContact CB-CG2 3.92Å; A192-V219 VanDerWaalsContact O-CG2 3.26Å; A192-V219 WeakPolarHBondContact O-CG2 3.35Å; L193-V219 HydrophobicContact CD2-CB 3.86Å; L193-V219 HydrophobicContact CD2-CG1 3.96Å; L193-V219 HydrophobicContact CD2-CG2 3.86Å; L193-V219 HydrophobicContact CG-CB 4.45Å; L193-V219 HydrophobicContact CG-CG1 4.06Å; L193-V219 HydrophobicContact CG-CG2 4.31Å; P215-V219 WeakPolarHBondContact O-CB 3.17Å; P215-V219 VanDerWaalsContact O-CG2 3.29Å; P215-V219 WeakPolarHBondContact O-CG2 3.49Å; P215-V219 PolarHBondContact O-N 3Å; V219-L221 VanDerWaalsContact C-N 3.31Å; V219-L221 PolarHBondContact O-N 2.89Å; V219-W222 PolarHBondContact O-N 3.48Å; V219-W222 VanDerWaalsContact O-N 3.08Å; V219-V223 HydrophobicContact CG1-CG2 4.47Å; V219-V223 WeakPolarHBondContact O-CG2 3.12Å; V219-V223 PolarHBondContact O-N 3.06Å; V219-P421 HydrophobicContact CG1-CB 4.03Å
220	G	92.5	Very high	81.8	Confident	39 Å²	39	69.9 Å²	69.9	40%	0.402	41%	0.413	S	S	.	.	H	α-helix	trans	-59.7	-37.2	178.6	0	0	0	0	0	113.8	I216 L217 L224	I216-G220 PolarHBondContact O-N 2.81Å; L217-G220 PolarHBondContact O-N 3.2Å; G220-L224 WeakPolarHBondContact O-CB 3.32Å; G220-L224 PolarHBondContact O-N 2.96Å
221	L	93	Very high	84.2	Confident	101 Å²	101	64.5 Å²	64.5	53%	0.529	39%	0.39	S	S	.	.	H	α-helix	trans	-67.3	-36.4	174.6	-74.7	171	0	0	0	112.5	L217 S218 V219 S225	L217-L221 HydrophobicContact CD1-CD1 4.21Å; L217-L221 HydrophobicContact CD1-CG 4.22Å; L217-L221 HydrophobicContact CG-CD1 4.05Å; L217-L221 HydrophobicContact CG-CG 4.48Å; L217-L221 WeakPolarHBondContact O-CB 3.29Å; L217-L221 VanDerWaalsContact O-CG 3.24Å; L217-L221 WeakPolarHBondContact O-CG 3.46Å; L217-L221 PolarHBondContact O-N 2.83Å; S218-L221 PolarHBondContact O-N 2.98Å; V219-L221 VanDerWaalsContact C-N 3.31Å; V219-L221 PolarHBondContact O-N 2.89Å; L221-S225 WeakPolarHBondContact O-CB 3.42Å; L221-S225 PolarHBondContact O-N 2.67Å
222	W	92.3	Very high	86.4	Confident	100 Å²	100	63.9 Å²	63.9	38%	0.379	38%	0.382	S	S	.	.	H	α-helix	trans	-74.5	-36.6	176.3	-72.1	119.9	0	0	0	113	S218 V219 L224 S225 G226 W418 P421 F422	S218-W222 PolarHBondContact O-N 3.45Å; V219-W222 PolarHBondContact O-N 3.48Å; V219-W222 VanDerWaalsContact O-N 3.08Å; W222-L224 VanDerWaalsContact C-N 3.35Å; W222-S225 WeakPolarHBondContact O-CB 3.48Å; W222-S225 PolarHBondContact O-N 3.01Å; W222-G226 PolarHBondContact O-N 3.16Å; W222-W418 HydrophobicContact CB-CB 4.48Å; W222-W418 HydrophobicContact CD2-CB 3.38Å; W222-W418 HydrophobicContact CD2-CG 4.4Å; W222-W418 HydrophobicContact CE3-CB 3.88Å; W222-W418 HydrophobicContact CG-CB 3.63Å; W222-W418 HydrophobicContact CH2-CB 4.22Å; W222-W418 HydrophobicContact CH2-CG 4.34Å; W222-W418 HydrophobicContact CZ2-CB 3.76Å; W222-W418 HydrophobicContact CZ2-CG 4.19Å; W222-W418 HydrophobicContact CZ3-CB 4.27Å; W222-W418 HydrophobicContact CZ3-CE3 4.44Å; W222-P421 HydrophobicContact CB-CB 3.83Å; W222-P421 HydrophobicContact CB-CG 3.6Å; W222-P421 HydrophobicContact CG-CG 4.39Å; W222-F422 WeakPolarHBondContact O-CA 3.04Å
223	V	94.8	Very high	87.9	Confident	16 Å²	16	63.6 Å²	63.6	10%	0.097	37%	0.365	C	S	.	.	H	α-helix	trans	-58.2	-48	168.4	177.3	0	0	0	0	110.5	I189 V219 S225 G226 I227 P421 G425 I428	I189-V223 HydrophobicContact CD1-CG1 4.37Å; I189-V223 HydrophobicContact CD1-CG2 3.85Å; I189-V223 HydrophobicContact CG1-CG2 3.8Å; V219-V223 HydrophobicContact CG1-CG2 4.47Å; V219-V223 WeakPolarHBondContact O-CG2 3.12Å; V219-V223 PolarHBondContact O-N 3.06Å; V223-S225 VanDerWaalsContact C-N 3.3Å; V223-S225 PolarHBondContact O-N 2.86Å; V223-G226 PolarHBondContact O-N 3.29Å; V223-I227 HydrophobicContact CG1-CD1 4.12Å; V223-I227 WeakPolarHBondContact O-CG1 3.38Å; V223-I227 PolarHBondContact O-N 3.17Å; V223-P421 VanDerWaalsContact CA-O 3.24Å; V223-P421 WeakPolarHBondContact CA-O 3.14Å; V223-P421 HydrophobicContact CG2-CB 3.64Å; V223-P421 WeakPolarHBondContact CG2-O 3.34Å; V223-G425 WeakPolarHBondContact O-CA 3.27Å; V223-I428 HydrophobicContact CG1-CD1 4.04Å
224	L	95.7	Very high	89.3	Confident	97 Å²	97	56.6 Å²	56.6	51%	0.508	33%	0.332	S	S	.	.	H	α-helix	trans	-63	-36.9	176	-175.6	62.2	0	0	0	112	G220 W222 I227 V228	G220-L224 WeakPolarHBondContact O-CB 3.32Å; G220-L224 PolarHBondContact O-N 2.96Å; W222-L224 VanDerWaalsContact C-N 3.35Å; L224-I227 PolarHBondContact O-N 3.47Å; L224-V228 HydrophobicContact CD1-CG2 4.3Å; L224-V228 HydrophobicContact CG-CG2 4.41Å; L224-V228 WeakPolarHBondContact O-CB 3.49Å; L224-V228 VanDerWaalsContact O-CG2 3.26Å; L224-V228 WeakPolarHBondContact O-CG2 3.35Å; L224-V228 PolarHBondContact O-N 2.98Å
225	S	93.8	Very high	90.2	Very high	46 Å²	46	61.8 Å²	61.8	32%	0.322	35%	0.345	S	S	.	.	H	α-helix	trans	-61.6	-43.3	174.9	-169	0	0	0	0	111.9	L221 W222 V223 V228 A229	L221-S225 WeakPolarHBondContact O-CB 3.42Å; L221-S225 PolarHBondContact O-N 2.67Å; W222-S225 WeakPolarHBondContact O-CB 3.48Å; W222-S225 PolarHBondContact O-N 3.01Å; V223-S225 VanDerWaalsContact C-N 3.3Å; V223-S225 PolarHBondContact O-N 2.86Å; S225-V228 PolarHBondContact O-N 3Å; S225-A229 VanDerWaalsContact O-CB 3.29Å; S225-A229 WeakPolarHBondContact O-CB 3.21Å; S225-A229 PolarHBondContact O-N 3.18Å
226	G	92.5	Very high	90.7	Very high	0 Å²	0	65.5 Å²	65.5	0%	0	36%	0.355	C	S	.	.	H	α-helix	trans	-59.3	-51.9	173.3	0	0	0	0	0	112.4	W222 V223 V228 A229 F230 F422	W222-G226 PolarHBondContact O-N 3.16Å; V223-G226 PolarHBondContact O-N 3.29Å; G226-V228 VanDerWaalsContact C-N 3.31Å; G226-V228 PolarHBondContact O-N 3.05Å; G226-A229 PolarHBondContact O-N 3.47Å; G226-F230 WeakPolarHBondContact O-CD2 3.37Å; G226-F230 PolarHBondContact O-N 2.74Å; G226-F422 WeakPolarHBondContact CA-O 3.45Å
227	I	95.3	Very high	90.4	Very high	48 Å²	48	61.9 Å²	61.9	25%	0.246	34%	0.338	C	S	.	.	H	α-helix	trans	-55	-46.2	176.4	-67.3	170	0	0	0	111	V223 L224 L231 G425 I428 Y429	V223-I227 HydrophobicContact CG1-CD1 4.12Å; V223-I227 WeakPolarHBondContact O-CG1 3.38Å; V223-I227 PolarHBondContact O-N 3.17Å; L224-I227 PolarHBondContact O-N 3.47Å; I227-L231 WeakPolarHBondContact O-CB 3.24Å; I227-L231 PolarHBondContact O-N 3.29Å; I227-G425 VanDerWaalsContact CG1-O 3.22Å; I227-G425 WeakPolarHBondContact CG1-O 3.3Å; I227-I428 HydrophobicContact CD1-CG2 4.18Å; I227-Y429 HydrophobicContact CG2-CD2 4.16Å
228	V	95.4	Very high	90.2	Very high	73 Å²	73	62.9 Å²	62.9	44%	0.442	33%	0.334	S	S	.	.	H	α-helix	trans	-68.9	-39.7	-179.9	170.3	0	0	0	0	111.8	L224 S225 G226 L231 V232	L224-V228 HydrophobicContact CD1-CG2 4.3Å; L224-V228 HydrophobicContact CG-CG2 4.41Å; L224-V228 WeakPolarHBondContact O-CB 3.49Å; L224-V228 VanDerWaalsContact O-CG2 3.26Å; L224-V228 WeakPolarHBondContact O-CG2 3.35Å; L224-V228 PolarHBondContact O-N 2.98Å; S225-V228 PolarHBondContact O-N 3Å; G226-V228 VanDerWaalsContact C-N 3.31Å; G226-V228 PolarHBondContact O-N 3.05Å; V228-L231 PolarHBondContact O-N 3.38Å; V228-V232 HydrophobicContact CG1-CG2 4.37Å; V228-V232 WeakPolarHBondContact O-CB 3.44Å; V228-V232 VanDerWaalsContact O-CG2 3.29Å; V228-V232 WeakPolarHBondContact O-CG2 3.47Å; V228-V232 PolarHBondContact O-N 2.93Å
229	A	90.9	Very high	90.1	Very high	32 Å²	32	67.5 Å²	67.5	26%	0.264	35%	0.349	S	S	.	.	H	α-helix	trans	-62	-46.5	177.1	0	0	0	0	0	111.2	S225 G226 L231 V232 V233 F422	S225-A229 VanDerWaalsContact O-CB 3.29Å; S225-A229 WeakPolarHBondContact O-CB 3.21Å; S225-A229 PolarHBondContact O-N 3.18Å; G226-A229 PolarHBondContact O-N 3.47Å; A229-L231 PolarHBondContact O-N 3.05Å; A229-V232 PolarHBondContact O-N 3.38Å; A229-V233 WeakPolarHBondContact O-CG2 3.34Å; A229-V233 PolarHBondContact O-N 2.92Å; A229-F422 HydrophobicContact CB-CE2 3.79Å; A229-F422 HydrophobicContact CB-CZ 3.7Å
230	F	91	Very high	89.8	Confident	16 Å²	16	71.3 Å²	71.3	7%	0.07	37%	0.372	C	S	.	.	H	α-helix	trans	-64	-40.2	176.9	-85.2	-111.3	0	0	0	112.1	G226 V232 V233 E234 L321 A324 A325 Y429 V430	G226-F230 WeakPolarHBondContact O-CD2 3.37Å; G226-F230 PolarHBondContact O-N 2.74Å; F230-V232 PolarHBondContact O-N 3.16Å; F230-V233 PolarHBondContact O-N 3.16Å; F230-E234 WeakPolarHBondContact O-CB 3.46Å; F230-E234 PolarHBondContact O-N 3.14Å; F230-L321 HydrophobicContact CD1-CB 4.4Å; F230-L321 HydrophobicContact CD1-CD2 4.18Å; F230-L321 WeakPolarHBondContact CE1-O 3.46Å; F230-A324 HydrophobicContact CE1-CB 4.37Å; F230-A324 HydrophobicContact CZ-CB 4.31Å; F230-A325 HydrophobicContact CE1-CB 3.69Å; F230-A325 HydrophobicContact CZ-CB 3.89Å; F230-Y429 HydrophobicContact CB-CD1 3.64Å; F230-Y429 HydrophobicContact CB-CD2 4.23Å; F230-Y429 HydrophobicContact CB-CE1 4.26Å; F230-Y429 HydrophobicContact CB-CG 3.63Å; F230-Y429 HydrophobicContact CD1-CD1 4.42Å; F230-V430 HydrophobicContact CD1-CG2 4.16Å; F230-V430 HydrophobicContact CE1-CG2 4.12Å
231	L	92.8	Very high	89	Confident	76 Å²	76	73.4 Å²	73.4	40%	0.398	37%	0.37	S	S	.	.	H	α-helix	trans	-59.4	-44	171.7	-171	156.7	0	0	0	112.3	I227 V228 A229 E234 K235 Y429	I227-L231 WeakPolarHBondContact O-CB 3.24Å; I227-L231 PolarHBondContact O-N 3.29Å; V228-L231 PolarHBondContact O-N 3.38Å; A229-L231 PolarHBondContact O-N 3.05Å; L231-E234 PolarHBondContact O-N 3.35Å; L231-K235 WeakPolarHBondContact O-CB 3.32Å; L231-K235 PolarHBondContact O-N 2.75Å; L231-Y429 WeakPolarHBondContact CA-OH 3.41Å; L231-Y429 HydrophobicContact CB-CD2 4.43Å; L231-Y429 HydrophobicContact CB-CE2 3.62Å; L231-Y429 HydrophobicContact CD1-CE2 4.35Å; L231-Y429 HydrophobicContact CG-CE2 4.19Å
232	V	91.4	Very high	87.5	Confident	85 Å²	85	71.3 Å²	71.3	52%	0.515	37%	0.374	S	S	.	.	H	α-helix	trans	-66	-45.5	179.1	167.6	0	0	0	0	111	V228 A229 F230 K235 F236	V228-V232 HydrophobicContact CG1-CG2 4.37Å; V228-V232 WeakPolarHBondContact O-CB 3.44Å; V228-V232 VanDerWaalsContact O-CG2 3.29Å; V228-V232 WeakPolarHBondContact O-CG2 3.47Å; V228-V232 PolarHBondContact O-N 2.93Å; A229-V232 PolarHBondContact O-N 3.38Å; F230-V232 PolarHBondContact O-N 3.16Å; V232-K235 PolarHBondContact O-N 3.32Å; V232-F236 VanDerWaalsContact O-CB 3.28Å; V232-F236 WeakPolarHBondContact O-CB 3.38Å; V232-F236 PolarHBondContact O-N 3.02Å
233	V	85.1	Confident	85.5	Confident	71 Å²	71	69.5 Å²	69.5	43%	0.43	39%	0.386	S	S	.	.	H	α-helix	trans	-59.5	-48.9	175	171.9	0	0	0	0	110.2	A229 F230 K235 F236 V237 L321	A229-V233 WeakPolarHBondContact O-CG2 3.34Å; A229-V233 PolarHBondContact O-N 2.92Å; F230-V233 PolarHBondContact O-N 3.16Å; V233-K235 PolarHBondContact O-N 2.64Å; V233-F236 PolarHBondContact O-N 3.29Å; V233-V237 HydrophobicContact CG1-CG2 4.4Å; V233-V237 WeakPolarHBondContact O-CG2 3.35Å; V233-V237 PolarHBondContact O-N 2.92Å; V233-L321 HydrophobicContact CB-CD2 4.17Å; V233-L321 HydrophobicContact CG1-CD2 3.84Å
234	E	87.3	Confident	83.3	Confident	13 Å²	13	76.3 Å²	76.3	6%	0.061	42%	0.416	C	S	.	.	H	α-helix	trans	-59.9	-49.7	178.8	-178.2	158.3	-162	0	0	111.4	F230 L231 F236 V237 R238 V317 L321 Y429	F230-E234 WeakPolarHBondContact O-CB 3.46Å; F230-E234 PolarHBondContact O-N 3.14Å; L231-E234 PolarHBondContact O-N 3.35Å; E234-F236 VanDerWaalsContact C-N 3.28Å; E234-F236 PolarHBondContact O-N 3.41Å; E234-V237 PolarHBondContact O-N 3.43Å; E234-R238 VanDerWaalsContact CD-NE 3.28Å; E234-R238 HydrophobicContact CG-CG 4.05Å; E234-R238 VanDerWaalsContact CG-NE 3.33Å; E234-R238 WeakPolarHBondContact O-CB 3.43Å; E234-R238 VanDerWaalsContact O-CG 3.31Å; E234-R238 WeakPolarHBondContact O-CG 3.32Å; E234-R238 PolarHBondContact O-N 2.89Å; E234-R238 IonicContact OE1-CZ 3.15Å; E234-R238 IonicContact OE1-NE 2.81Å; E234-R238 PolarHBondContact OE1-NE 3.04Å; E234-R238 IonicContact OE1-NH2 2.74Å; E234-R238 PolarHBondContact OE1-NH2 3.14Å; E234-R238 IonicContact OE2-CZ 3.69Å; E234-R238 IonicContact OE2-NE 3.99Å; E234-R238 IonicContact OE2-NH2 2.87Å; E234-R238 PolarHBondContact OE2-NH2 3.34Å; E234-V317 HydrophobicContact CB-CG1 4.39Å; E234-V317 HydrophobicContact CG-CG1 3.8Å; E234-L321 HydrophobicContact CB-CD1 3.65Å; E234-L321 HydrophobicContact CB-CD2 4Å; E234-L321 HydrophobicContact CB-CG 4.37Å; E234-L321 HydrophobicContact CG-CD1 3.82Å; E234-Y429 HydrophobicContact CB-CE1 4.38Å; E234-Y429 WeakPolarHBondContact OE2-CE1 3.27Å; E234-Y429 PolarHBondContact OE2-OH 3.42Å
235	K	87.3	Confident	80.7	Confident	145 Å²	145	74.9 Å²	74.9	63%	0.63	43%	0.425	S	S	*	.	H	α-helix	trans	-60.7	-38.7	-179.6	-172.8	173.3	-178	176.8	0	111.6	L231 V232 V233 H239	L231-K235 WeakPolarHBondContact O-CB 3.32Å; L231-K235 PolarHBondContact O-N 2.75Å; V232-K235 PolarHBondContact O-N 3.32Å; V233-K235 PolarHBondContact O-N 2.64Å; K235-H239 VanDerWaalsContact O-CB 3.3Å; K235-H239 WeakPolarHBondContact O-CB 3.33Å; K235-H239 PolarHBondContact O-N 3.36Å
236	F	86	Confident	78.2	Confident	136 Å²	136	79.8 Å²	79.8	60%	0.596	44%	0.443	S	S	*	.	H	α-helix	trans	-65.4	-49.7	174.9	179.9	-99.8	0	0	0	111.8	V232 V233 E234 R238 H239 V240	V232-F236 VanDerWaalsContact O-CB 3.28Å; V232-F236 WeakPolarHBondContact O-CB 3.38Å; V232-F236 PolarHBondContact O-N 3.02Å; V233-F236 PolarHBondContact O-N 3.29Å; E234-F236 VanDerWaalsContact C-N 3.28Å; E234-F236 PolarHBondContact O-N 3.41Å; F236-R238 PolarHBondContact O-N 2.81Å; F236-H239 WeakPolarHBondContact O-CB 3.33Å; F236-H239 PolarHBondContact O-N 2.91Å; F236-H239 VanDerWaalsContact O-N 3.1Å; F236-V240 HydrophobicContact CD1-CG2 4.34Å; F236-V240 HydrophobicContact CE1-CG2 3.93Å; F236-V240 HydrophobicContact CE2-CG2 4.17Å; F236-V240 HydrophobicContact CZ-CG2 3.84Å; F236-V240 WeakPolarHBondContact O-CG2 3.38Å; F236-V240 PolarHBondContact O-N 3.49Å
237	V	79.6	Confident	75.7	Confident	33 Å²	33	85.3 Å²	85.3	20%	0.2	48%	0.481	C	S	.	.	H	α-helix	trans	-64.6	-41.1	179.3	178	0	0	0	0	111.3	V233 E234 H239 V240 K241 V317	V233-V237 HydrophobicContact CG1-CG2 4.4Å; V233-V237 WeakPolarHBondContact O-CG2 3.35Å; V233-V237 PolarHBondContact O-N 2.92Å; E234-V237 PolarHBondContact O-N 3.43Å; V237-H239 VanDerWaalsContact C-N 3.3Å; V237-H239 PolarHBondContact O-N 3.32Å; V237-V240 PolarHBondContact O-N 3.28Å; V237-K241 HydrophobicContact CG1-CD 4.34Å; V237-K241 HydrophobicContact CG1-CG 4.42Å; V237-K241 WeakPolarHBondContact O-CB 3.08Å; V237-K241 PolarHBondContact O-N 2.81Å; V237-V317 HydrophobicContact CB-CG1 3.72Å; V237-V317 HydrophobicContact CB-CG2 4.46Å; V237-V317 HydrophobicContact CG1-CB 4.31Å; V237-V317 HydrophobicContact CG1-CG1 3.71Å; V237-V317 HydrophobicContact CG1-CG2 3.81Å
238	R	82.4	Confident	73.4	Confident	132 Å²	132	91.3 Å²	91.3	50%	0.498	51%	0.508	S	S	.	.	H	α-helix	trans	-60.2	-37.9	171.8	-71.5	-174.8	-162.9	162.9	5	111.8	E234 F236 G242 V317	E234-R238 VanDerWaalsContact CD-NE 3.28Å; E234-R238 HydrophobicContact CG-CG 4.05Å; E234-R238 VanDerWaalsContact CG-NE 3.33Å; E234-R238 WeakPolarHBondContact O-CB 3.43Å; E234-R238 VanDerWaalsContact O-CG 3.31Å; E234-R238 WeakPolarHBondContact O-CG 3.32Å; E234-R238 PolarHBondContact O-N 2.89Å; E234-R238 IonicContact OE1-CZ 3.15Å; E234-R238 IonicContact OE1-NE 2.81Å; E234-R238 PolarHBondContact OE1-NE 3.04Å; E234-R238 IonicContact OE1-NH2 2.74Å; E234-R238 PolarHBondContact OE1-NH2 3.14Å; E234-R238 IonicContact OE2-CZ 3.69Å; E234-R238 IonicContact OE2-NE 3.99Å; E234-R238 IonicContact OE2-NH2 2.87Å; E234-R238 PolarHBondContact OE2-NH2 3.34Å; F236-R238 PolarHBondContact O-N 2.81Å; R238-G242 VanDerWaalsContact O-CA 3.3Å; R238-G242 WeakPolarHBondContact O-CA 3.41Å; R238-G242 PolarHBondContact O-N 3.09Å; R238-V317 HydrophobicContact CG-CG2 4.06Å
239	H	84.5	Confident	70.7	Confident	150 Å²	150	91 Å²	91	69%	0.694	52%	0.519	S	S	*	.	H	α-helix	trans	-68.6	-44.7	177.1	-173.4	68.3	0	0	0	112	K235 F236 V237 G243	K235-H239 VanDerWaalsContact O-CB 3.3Å; K235-H239 WeakPolarHBondContact O-CB 3.33Å; K235-H239 PolarHBondContact O-N 3.36Å; F236-H239 WeakPolarHBondContact O-CB 3.33Å; F236-H239 PolarHBondContact O-N 2.91Å; F236-H239 VanDerWaalsContact O-N 3.1Å; V237-H239 VanDerWaalsContact C-N 3.3Å; V237-H239 PolarHBondContact O-N 3.32Å; H239-G243 PolarHBondContact O-N 2.87Å
240	V	82.6	Confident	68.6	Low	89 Å²	89	97.4 Å²	97.4	54%	0.539	54%	0.543	S	S	.	.	H	α-helix	trans	-65.7	-45.2	178.2	174.1	0	0	0	0	111.7	F236 V237	F236-V240 HydrophobicContact CD1-CG2 4.34Å; F236-V240 HydrophobicContact CE1-CG2 3.93Å; F236-V240 HydrophobicContact CE2-CG2 4.17Å; F236-V240 HydrophobicContact CZ-CG2 3.84Å; F236-V240 WeakPolarHBondContact O-CG2 3.38Å; F236-V240 PolarHBondContact O-N 3.49Å; V237-V240 PolarHBondContact O-N 3.28Å
241	K	75.4	Confident	66.1	Low	82 Å²	82	100.3 Å²	100.3	36%	0.357	58%	0.578	S	S	.	*	H	α-helix	trans	-74.1	-34	177.1	-71.3	-165.7	170.2	-157.3	0	112.9	V237 G243 D314 L315	V237-K241 HydrophobicContact CG1-CD 4.34Å; V237-K241 HydrophobicContact CG1-CG 4.42Å; V237-K241 WeakPolarHBondContact O-CB 3.08Å; V237-K241 PolarHBondContact O-N 2.81Å; K241-G243 PolarHBondContact O-N 2.87Å; K241-D314 IonicContact NZ-OD1 3.22Å; K241-D314 PolarHBondContact NZ-OD1 2.91Å; K241-L315 PolarHBondContact NZ-O 2.74Å
242	G	60.5	Low	64.1	Low	58 Å²	58	102.9 Å²	102.9	60%	0.598	59%	0.588	S	S	*	*	H	α-helix	trans	-69.5	-10.6	-179.6	0	0	0	0	0	115.2	R238 H244	R238-G242 VanDerWaalsContact O-CA 3.3Å; R238-G242 WeakPolarHBondContact O-CA 3.41Å; R238-G242 PolarHBondContact O-N 3.09Å; G242-H244 PolarHBondContact O-N 2.99Å
243	G	51.7	Low	61.8	Low	61 Å²	61	103.9 Å²	103.9	63%	0.629	61%	0.605	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.6	-6.9	178	0	0	0	0	0	116	H239 K241	H239-G243 PolarHBondContact O-N 2.87Å; K241-G243 PolarHBondContact O-N 2.87Å
244	H	47.1	Very low	60.2	Low	159 Å²	159	107 Å²	107	74%	0.736	62%	0.615	S	S	*	*	T	Hydrogen-bonded Turn	trans	-116.7	40.1	-177.3	-82.6	86.3	0	0	0	113.9	G242 H246	G242-H244 PolarHBondContact O-N 2.99Å; H244-H246 PolarHBondContact O-N 3.24Å
245	G	42.3	Very low	58.4	Low	68 Å²	68	111.8 Å²	111.8	70%	0.701	65%	0.649	S	S	*	*			trans	-85	68.8	171.5	0	0	0	0	0	114	S247	G245-S247 PolarHBondContact O-N 2.74Å; G245-S247 VanDerWaalsContact O-N 3.09Å
246	H	42	Very low	56.4	Low	149 Å²	149	113.1 Å²	113.1	69%	0.69	66%	0.657	S	S	*	*			trans	-73.8	96.1	172.3	-77.4	123.5	0	0	0	111.6	H244 H248	H244-H246 PolarHBondContact O-N 3.24Å; H246-H248 VanDerWaalsContact C-N 3.34Å; H246-H248 PolarHBondContact O-N 2.77Å
247	S	38.7	Very low	54.5	Low	115 Å²	115	112.9 Å²	112.9	80%	0.804	67%	0.667	S	S	*	*			trans	-75.6	79.2	169.8	49.3	0	0	0	0	111.8	G245 G249	G245-S247 PolarHBondContact O-N 2.74Å; G245-S247 VanDerWaalsContact O-N 3.09Å; S247-G249 PolarHBondContact O-N 2.84Å
248	H	46.5	Very low	52.8	Low	174 Å²	174	123.2 Å²	123.2	81%	0.806	70%	0.703	S	S	*	*			trans	-74.2	69.4	169	-82.4	-70.6	0	0	0	112	H246 H250	H246-H248 VanDerWaalsContact C-N 3.34Å; H246-H248 PolarHBondContact O-N 2.77Å; H248-H250 PolarHBondContact O-N 3.23Å
249	G	39.3	Very low	50.6	Low	67 Å²	67	120.8 Å²	120.8	69%	0.691	72%	0.718	S	S	*	*			trans	-95.8	67.9	174.4	0	0	0	0	0	113.1	S247	S247-G249 PolarHBondContact O-N 2.84Å
250	H	46.9	Very low	48.7	Very low	166 Å²	166	117.9 Å²	117.9	77%	0.769	72%	0.715	S	S	*	*			trans	-144.8	94.7	163	-99.5	-50.3	0	0	0	111.8	H248 H252	H248-H250 PolarHBondContact O-N 3.23Å; H250-H252 AromaticContact ND1-CD2 3.92Å; H250-H252 PolarHBondContact O-N 3.09Å
251	G	39.6	Very low	46.9	Very low	77 Å²	77	122.4 Å²	122.4	79%	0.794	73%	0.73	S	S	*	*			trans	-81.5	106	165.2	0	0	0	0	0	110.7
252	H	50.1	Low	45.3	Very low	131 Å²	131	121.7 Å²	121.7	61%	0.606	75%	0.745	S	S	*	*			trans	-136.5	82.6	166.4	-80.9	-56.7	0	0	0	110.7	H250 H254	H250-H252 AromaticContact ND1-CD2 3.92Å; H250-H252 PolarHBondContact O-N 3.09Å; H252-H254 AromaticContact CG-NE2 3.95Å; H252-H254 PolarHBondContact O-N 3.24Å
253	A	43.4	Very low	44.3	Very low	105 Å²	105	128.8 Å²	128.8	87%	0.868	76%	0.763	S	S	*	*			trans	-80.2	95.2	167.9	0	0	0	0	0	109.8	S255	A253-S255 PolarHBondContact O-N 3.01Å
254	H	50.6	Low	43.7	Very low	138 Å²	138	129.4 Å²	129.4	64%	0.639	77%	0.769	S	S	*	*			trans	-91	91.2	172.8	-65	-66	0	0	0	110.8	H252 H256	H252-H254 AromaticContact CG-NE2 3.95Å; H252-H254 PolarHBondContact O-N 3.24Å; H254-H256 PolarHBondContact O-N 3.07Å
255	S	49.2	Very low	43.3	Very low	112 Å²	112	132.6 Å²	132.6	78%	0.783	77%	0.774	S	S	*	*			trans	-78.2	99.2	170.5	60.1	0	0	0	0	110.7	A253 T257	A253-S255 PolarHBondContact O-N 3.01Å; S255-T257 PolarHBondContact O-N 3.4Å
256	H	45.1	Very low	43	Very low	173 Å²	173	137.6 Å²	137.6	80%	0.801	78%	0.78	S	S	*	*			trans	-79	114.4	170.9	-67.1	-93.1	0	0	0	111	H254	H254-H256 PolarHBondContact O-N 3.07Å
257	T	46.8	Very low	42.9	Very low	132 Å²	132	136.9 Å²	136.9	81%	0.81	78%	0.776	S	S	*	*			trans	-141.8	98.2	162.8	8.6	0	0	0	0	111.8	S255	S255-T257 PolarHBondContact O-N 3.4Å
258	R	43.6	Very low	42.8	Very low	250 Å²	250	141.4 Å²	141.4	94%	0.943	78%	0.776	S	S	*	*			trans	-1.5	121.4	161	-72	172.2	158.4	166.3	-7.2	117.4
259	G	37	Very low	42.3	Very low	80 Å²	80	137.4 Å²	137.4	83%	0.825	77%	0.768	S	S	*	*			trans	-79.7	141.2	151.1	0	0	0	0	0	111.6
260	S	43.6	Very low	42.1	Very low	90 Å²	90	139.6 Å²	139.6	63%	0.629	77%	0.768	S	S	*	*			trans	-169	142.5	146.8	-165.1	0	0	0	0	110.2
261	H	44.7	Very low	41.6	Very low	184 Å²	184	139.9 Å²	139.9	85%	0.852	77%	0.767	S	S	*	*			trans	66.6	143.3	175.9	-42	-71	0	0	0	116.2
262	G	41.6	Very low	41.5	Very low	66 Å²	66	143.1 Å²	143.1	68%	0.68	76%	0.761	S	S	*	*			cis	150.2	117.2	-6.6	0	0	0	0	0	112.6
263	H	41.4	Very low	40.7	Very low	208 Å²	208	145.5 Å²	145.5	96%	0.963	77%	0.77	S	S	*	*			trans	61	128.2	168.5	-85.4	-93.3	0	0	0	120.6
264	G	38.9	Very low	40.2	Very low	73 Å²	73	147.1 Å²	147.1	75%	0.753	76%	0.759	S	S	*	*				132.9	90.3	121.1	0	0	0	0	0	120.7
265	R	37.6	Very low	39.4	Very low	227 Å²	227	145.5 Å²	145.5	86%	0.857	76%	0.764	S	S	*	*			trans	71.2	89	133.6	-159.6	178.3	-171.4	-176.3	1.6	121.3
266	Q	36.6	Very low	38.7	Very low	173 Å²	173	144 Å²	144	81%	0.808	75%	0.753	S	S	*	*				41.9	146.7	105.3	-145.9	177.3	10	0	0	122.4
267	E	39.9	Very low	38.2	Very low	133 Å²	133	143.4 Å²	143.4	62%	0.621	75%	0.75	S	S	*	*			trans	86.1	140	165	-64.3	-154.9	117.5	0	0	117.9
268	R	35.6	Very low	37.7	Very low	210 Å²	210	144.9 Å²	144.9	79%	0.792	75%	0.748	S	S	*	*			cis	-162.1	-179.2	-17.6	-146.3	169.4	-178.5	161.2	-9.6	110.1
269	S	35.8	Very low	37.2	Very low	91 Å²	91	141.1 Å²	141.1	64%	0.636	74%	0.741	S	S	*	*			trans	-50.8	169.8	179.7	64	0	0	0	0	116.3
270	T	36.3	Very low	37.1	Very low	113 Å²	113	144.9 Å²	144.9	69%	0.693	74%	0.737	S	S	*	*			cis	-174.2	152.8	44.6	-18.1	0	0	0	0	111.8
271	K	35.2	Very low	36.6	Very low	172 Å²	172	148.9 Å²	148.9	75%	0.748	74%	0.743	S	S	*	*			trans	45.3	135.6	138.1	-100.6	-178.1	153.5	-141	0	119.9
272	E	38	Very low	36	Very low	144 Å²	144	147.8 Å²	147.8	67%	0.673	74%	0.739	S	S	*	*			cis	-164.8	147.5	47	-103.9	156.5	-174	0	0	110.1
273	K	34.2	Very low	35.6	Very low	181 Å²	181	149.8 Å²	149.8	79%	0.787	74%	0.738	S	S	*	*				42.6	143.1	107.6	-80.1	-167.7	165.8	-138.8	0	117.2
274	Q	33.2	Very low	35.4	Very low	139 Å²	139	151.5 Å²	151.5	65%	0.65	74%	0.736	S	S	*	*			cis	-177.7	152.4	-3.1	173.3	178.8	-25.9	0	0	108.7
275	S	33.7	Very low	35.4	Very low	105 Å²	105	151.7 Å²	151.7	73%	0.734	74%	0.738	S	S	*	*			trans	58.8	159.6	164.2	45.5	0	0	0	0	119.1
276	S	32.8	Very low	35.3	Very low	79 Å²	79	147.4 Å²	147.4	55%	0.552	74%	0.737	S	S	*	*			cis	-169.6	162.8	-21	49.8	0	0	0	0	108.2
277	E	35.9	Very low	35.6	Very low	161 Å²	161	148.8 Å²	148.8	75%	0.752	74%	0.743	S	S	*	*			trans	58.9	159.9	160.7	-66.5	125	-173.3	0	0	117.7
278	E	35.9	Very low	35.5	Very low	164 Å²	164	150.6 Å²	150.6	77%	0.766	75%	0.749	S	S	*	*			cis	-157.2	155.9	-17.8	-113	168.3	177.5	0	0	108.9
279	E	33.7	Very low	35.9	Very low	170 Å²	170	152.8 Å²	152.8	79%	0.794	76%	0.757	S	S	*	*			trans	49.1	148.7	150.3	-74	-162.6	135.8	0	0	127.8
280	E	34.4	Very low	36	Very low	159 Å²	159	159.4 Å²	159.4	74%	0.743	77%	0.768	S	S	*	*			trans	71.5	113.5	153.8	-69.5	-156.1	123.2	0	0	125.7
281	K	32.9	Very low	36.1	Very low	174 Å²	174	158.1 Å²	158.1	76%	0.757	78%	0.777	S	S	*	*				18	138	125.5	-72.6	176.9	175.4	171	0	117.9
282	E	32.6	Very low	36.3	Very low	161 Å²	161	154 Å²	154	75%	0.752	78%	0.783	S	S	*	*			cis	-179.2	169.1	47.9	-152.2	-178.3	-145.8	0	0	112.4
283	T	33.3	Very low	36.2	Very low	108 Å²	108	152.1 Å²	152.1	66%	0.663	79%	0.787	S	S	*	*			trans	91.7	147.5	156.4	76.9	0	0	0	0	122
284	R	36.6	Very low	36.5	Very low	245 Å²	245	150.4 Å²	150.4	93%	0.925	79%	0.791	S	S	*	*			trans	82	131.3	171.1	-54.7	-180	175	-162.9	-2.7	116.1
285	G	39.5	Very low	37	Very low	77 Å²	77	149.9 Å²	149.9	79%	0.794	80%	0.798	S	S	*	*			cis	-167.3	161.6	-0.6	0	0	0	0	0	113.8
286	V	35	Very low	37.5	Very low	137 Å²	137	149.9 Å²	149.9	83%	0.83	80%	0.795	S	S	*	*			trans	-86	140.7	-171.7	172.3	0	0	0	0	112.4	K288	V286-K288 HydrophobicContact CG1-CB 4.39Å
287	Q	43.5	Very low	37.9	Very low	202 Å²	202	155.9 Å²	155.9	94%	0.944	81%	0.811	S	S	*	*			trans	-133.4	140.7	152.1	-113.3	-178.4	9.2	0	0	112.2
288	K	37	Very low	38.1	Very low	171 Å²	171	156 Å²	156	74%	0.743	82%	0.817	S	S	*	*			trans	-142.2	130.8	-163.4	171.1	-174.5	-175.7	175.1	0	108.7	V286	V286-K288 HydrophobicContact CG1-CB 4.39Å
289	R	44.1	Very low	38.7	Very low	255 Å²	255	150.9 Å²	150.9	96%	0.962	81%	0.808	S	S	*	*			trans	-146.7	146	160.3	-110.8	170.5	-176.7	-168	-2	111.8
290	R	39.1	Very low	39.2	Very low	230 Å²	230	148.9 Å²	148.9	87%	0.868	81%	0.81	S	S	*	*			trans	-106.5	150.7	-166.3	-81.1	169.9	143.6	179.8	-7.8	111.7
291	G	36.7	Very low	39.6	Very low	86 Å²	86	148.1 Å²	148.1	89%	0.887	82%	0.816	S	S	*	*				101.3	130.3	118.6	0	0	0	0	0	118.5
292	G	40.1	Very low	40	Very low	85 Å²	85	149.5 Å²	149.5	88%	0.876	82%	0.816	S	S	*	*			trans	161.5	121.3	169.2	0	0	0	0	0	111
293	S	36.4	Very low	40.4	Very low	106 Å²	106	146.6 Å²	146.6	74%	0.741	81%	0.812	S	S	*	*			trans	-111.2	142.1	-174.6	176.9	0	0	0	0	111.8
294	T	40.1	Very low	40.7	Very low	144 Å²	144	150.5 Å²	150.5	88%	0.883	82%	0.823	S	S	*	*			trans	179.3	162.2	133.1	24.6	0	0	0	0	111.9
295	V	44.3	Very low	40.9	Very low	129 Å²	129	146.1 Å²	146.1	78%	0.782	82%	0.817	S	S	*	*			trans	-130.9	168.4	-158.2	177.1	0	0	0	0	108.6
296	P	42.6	Very low	40.9	Very low	105 Å²	105	146.6 Å²	146.6	68%	0.682	81%	0.814	S	S	*	*			cis	-117.1	-178	-36.1	35.7	-21.2	0	0	0	112.1
297	K	43.3	Very low	41.1	Very low	205 Å²	205	148.4 Å²	148.4	89%	0.891	81%	0.813	S	S	*	*			trans	-158.4	120	142.6	-126.6	173.2	-175.4	177.6	0	113.4
298	D	38.8	Very low	41	Very low	162 Å²	162	147.9 Å²	147.9	87%	0.866	81%	0.811	S	S	*	*			trans	-65.6	133.8	172	-58.5	-73.4	0	0	0	111.3
299	G	48.8	Very low	41	Very low	57 Å²	57	147.1 Å²	147.1	59%	0.588	81%	0.81	S	S	*	*			trans	-123.9	137.9	167.9	0	0	0	0	0	108.9	V301	G299-V301 PolarHBondContact O-N 3.42Å
300	P	44.4	Very low	40.5	Very low	128 Å²	128	144.9 Å²	144.9	83%	0.831	81%	0.807	S	S	*	*			trans	-69.7	123.1	-169.6	27.3	-34.2	0	0	0	111.4	R302	P300-R302 PolarHBondContact O-N 3.37Å
301	V	43.5	Very low	40.5	Very low	144 Å²	144	145 Å²	145	87%	0.873	81%	0.808	S	S	*	*			trans	-66.3	96.9	163.8	178.3	0	0	0	0	107.5	G299 P303	G299-V301 PolarHBondContact O-N 3.42Å; V301-P303 WeakPolarHBondContact O-CD 3.26Å
302	R	40.7	Very low	41.1	Very low	202 Å²	202	144.1 Å²	144.1	76%	0.762	80%	0.799	S	S	*	*			trans	-72.4	120.4	176.7	-163	-178.7	-155.9	-138.9	4.5	108.4	P300 Q304	P300-R302 PolarHBondContact O-N 3.37Å; R302-Q304 PolarHBondContact O-N 2.91Å
303	P	39.8	Very low	42.1	Very low	101 Å²	101	143.3 Å²	143.3	66%	0.656	77%	0.774	S	S	*	*			trans	-66.9	124.2	176.5	27.4	-32.8	0	0	0	109.2	V301 N305	V301-P303 WeakPolarHBondContact O-CD 3.26Å; P303-N305 PolarHBondContact O-N 2.86Å
304	Q	40.3	Very low	43.9	Very low	190 Å²	190	144.8 Å²	144.8	89%	0.888	77%	0.773	S	S	*	*	S	Bend	trans	-78.8	27.9	179.7	-67.6	-178.6	-20.3	0	0	112.8	R302	R302-Q304 PolarHBondContact O-N 2.91Å
305	N	40.3	Very low	45.9	Very low	152 Å²	152	138 Å²	138	81%	0.813	73%	0.732	S	S	*	*			trans	-116.3	58.4	-171.6	-64.4	8.4	0	0	0	110.8	P303	P303-N305 PolarHBondContact O-N 2.86Å
306	A	40.7	Very low	47.9	Very low	88 Å²	88	138.5 Å²	138.5	73%	0.727	72%	0.72	S	S	*	*	S	Bend	trans	-149.9	3.1	-179.8	0	0	0	0	0	115.7
307	E	39.2	Very low	49.9	Very low	175 Å²	175	134.5 Å²	134.5	82%	0.818	69%	0.693	S	S	*	*	S	Bend	trans	-107.4	4.5	-172.9	-64	-170	171.5	0	0	114.6
308	E	39.8	Very low	52	Low	190 Å²	190	125.8 Å²	125.8	89%	0.888	66%	0.658	S	S	*	*	S	Bend	trans	-82.8	-14.7	179.6	-76.5	-170.5	129.6	0	0	115.2	K310	E308-K310 PolarHBondContact O-N 3.18Å
309	E	37.3	Very low	54.4	Low	155 Å²	155	118 Å²	118	72%	0.724	62%	0.617	S	S	*	*	T	Hydrogen-bonded Turn	trans	-90	12.9	-163.9	-157.5	160.9	-150.3	0	0	115.8	R382	E309-R382 IonicContact OE1-NH1 3.69Å
310	K	34.2	Very low	56.4	Low	208 Å²	208	120.1 Å²	120.1	90%	0.904	61%	0.607	S	S	*	*	T	Hydrogen-bonded Turn	trans	-132.3	19	177.9	-83	-165.6	176.1	-176.4	0	116.6	E308 G312	E308-K310 PolarHBondContact O-N 3.18Å; K310-G312 PolarHBondContact O-N 3.09Å
311	R	38.4	Very low	58.5	Low	233 Å²	233	114 Å²	114	88%	0.879	57%	0.568	S	S	*	*	S	Bend	trans	-76.4	114.1	161.9	-126.1	175.4	178.2	177.6	-2.6	108.3	L313	R311-L313 PolarHBondContact O-N 2.88Å
312	G	49	Very low	60.8	Low	68 Å²	68	107.2 Å²	107.2	70%	0.701	53%	0.526	S	S	*	.			trans	-54.2	138.2	174.8	0	0	0	0	0	110.5	K310 D314	K310-G312 PolarHBondContact O-N 3.09Å; G312-D314 PolarHBondContact O-N 3.47Å
313	L	62.4	Low	63.2	Low	68 Å²	68	98.8 Å²	98.8	36%	0.356	50%	0.497	S	S	.	.			trans	-65	96	-177.4	-112.6	135.7	0	0	0	109.8	R311 L315 Y320 L383	R311-L313 PolarHBondContact O-N 2.88Å; L313-L315 HydrophobicContact CD2-CB 4.22Å; L313-L315 PolarHBondContact O-N 3.42Å; L313-Y320 PolarHBondContact O-OH 3.15Å; L313-L383 HydrophobicContact CD2-CD1 4Å
314	D	73.1	Confident	65.6	Low	136 Å²	136	96 Å²	96	73%	0.727	48%	0.482	S	S	*	.			trans	-81.5	60.2	173.6	-163.4	17.6	0	0	0	110.9	K241 G312	K241-D314 IonicContact NZ-OD1 3.22Å; K241-D314 PolarHBondContact NZ-OD1 2.91Å; G312-D314 PolarHBondContact O-N 3.47Å
315	L	82.2	Confident	67.9	Low	3 Å²	3	87.1 Å²	87.1	2%	0.016	44%	0.441	C	S	.	.			trans	-72.1	132.8	178.9	-174.8	61.8	0	0	0	109.4	K241 L313 Y320 L323 L370 S373 C375	K241-L315 PolarHBondContact NZ-O 2.74Å; L313-L315 HydrophobicContact CD2-CB 4.22Å; L313-L315 PolarHBondContact O-N 3.42Å; L315-Y320 HydrophobicContact CB-CD2 4.15Å; L315-Y320 HydrophobicContact CB-CE2 3.63Å; L315-Y320 HydrophobicContact CD2-CD1 4.4Å; L315-Y320 HydrophobicContact CD2-CD2 4.14Å; L315-Y320 HydrophobicContact CD2-CE1 4.43Å; L315-Y320 HydrophobicContact CD2-CE2 4.19Å; L315-Y320 HydrophobicContact CD2-CG 4.26Å; L315-Y320 HydrophobicContact CG-CD2 4.17Å; L315-Y320 HydrophobicContact CG-CE2 4.14Å; L315-Y320 WeakPolarHBondContact O-CE2 3.39Å; L315-L323 HydrophobicContact CD2-CD1 4.18Å; L315-L370 HydrophobicContact CD1-CD2 4.49Å; L315-L370 HydrophobicContact CD2-CD2 4.33Å; L315-S373 VanDerWaalsContact CD1-CB 3.48Å; L315-C375 VanDerWaalsContact CD1-SG 3.57Å
316	R	86	Confident	70.3	Confident	139 Å²	139	80 Å²	80	53%	0.525	40%	0.403	S	S	.	.			trans	-58.9	154.9	170.8	-68.7	-179.6	-174.3	167.8	0.6	110.4	S318 G319 Q372 S373	R316-S318 WeakPolarHBondContact CB-OG 3.29Å; R316-S318 PolarHBondContact O-N 3.27Å; R316-G319 PolarHBondContact O-N 2.77Å; R316-Q372 PolarHBondContact NH1-O 3.19Å; R316-S373 WeakPolarHBondContact CG-O 3.43Å; R316-S373 PolarHBondContact N-O 3.29Å
317	V	86.6	Confident	72.7	Confident	21 Å²	21	79.5 Å²	79.5	13%	0.127	39%	0.388	C	S	.	.	H	α-helix	trans	-60	-35.7	-175.3	-166.5	0	0	0	0	111.9	E234 V237 R238 G319 Y320 L321	E234-V317 HydrophobicContact CB-CG1 4.39Å; E234-V317 HydrophobicContact CG-CG1 3.8Å; V237-V317 HydrophobicContact CB-CG1 3.72Å; V237-V317 HydrophobicContact CB-CG2 4.46Å; V237-V317 HydrophobicContact CG1-CB 4.31Å; V237-V317 HydrophobicContact CG1-CG1 3.71Å; V237-V317 HydrophobicContact CG1-CG2 3.81Å; R238-V317 HydrophobicContact CG-CG2 4.06Å; V317-G319 VanDerWaalsContact C-N 3.28Å; V317-G319 PolarHBondContact O-N 3.24Å; V317-Y320 PolarHBondContact O-N 2.66Å; V317-Y320 VanDerWaalsContact O-N 3.09Å; V317-L321 HydrophobicContact CG1-CD1 4.19Å; V317-L321 HydrophobicContact CG1-CG 4.36Å; V317-L321 WeakPolarHBondContact O-CG 3.49Å; V317-L321 PolarHBondContact O-N 2.92Å
318	S	85.5	Confident	74.9	Confident	21 Å²	21	72.1 Å²	72.1	15%	0.147	36%	0.357	C	S	.	.	H	α-helix	trans	-45.6	-47.3	169.4	48.8	0	0	0	0	113.4	R316 Y320 L321 N322 S373	R316-S318 WeakPolarHBondContact CB-OG 3.29Å; R316-S318 PolarHBondContact O-N 3.27Å; S318-Y320 PolarHBondContact O-N 2.99Å; S318-L321 PolarHBondContact O-N 3.33Å; S318-N322 WeakPolarHBondContact O-CB 3.45Å; S318-N322 PolarHBondContact O-N 3.47Å; S318-S373 PolarHBondContact OG-OG 2.9Å
319	G	90.2	Very high	77.3	Confident	0 Å²	0	63.2 Å²	63.2	0%	0	32%	0.315	C	S	.	.	H	α-helix	trans	-70	-31.4	-178.3	0	0	0	0	0	113.6	R316 V317 L323 S373	R316-G319 PolarHBondContact O-N 2.77Å; V317-G319 VanDerWaalsContact C-N 3.28Å; V317-G319 PolarHBondContact O-N 3.24Å; G319-L323 WeakPolarHBondContact O-CG 3.49Å; G319-L323 PolarHBondContact O-N 3.01Å; G319-S373 WeakPolarHBondContact CA-OG 3.38Å; G319-S373 PolarHBondContact N-OG 3.38Å; G319-S373 VanDerWaalsContact N-OG 3.16Å
320	Y	90.2	Very high	79.8	Confident	100 Å²	100	55.9 Å²	55.9	39%	0.392	28%	0.281	S	S	.	.	H	α-helix	trans	-72	-38.9	173.1	-76.1	-75.8	0	0	0	112.4	L313 L315 V317 S318 N322 A324	L313-Y320 PolarHBondContact O-OH 3.15Å; L315-Y320 HydrophobicContact CB-CD2 4.15Å; L315-Y320 HydrophobicContact CB-CE2 3.63Å; L315-Y320 HydrophobicContact CD2-CD1 4.4Å; L315-Y320 HydrophobicContact CD2-CD2 4.14Å; L315-Y320 HydrophobicContact CD2-CE1 4.43Å; L315-Y320 HydrophobicContact CD2-CE2 4.19Å; L315-Y320 HydrophobicContact CD2-CG 4.26Å; L315-Y320 HydrophobicContact CG-CD2 4.17Å; L315-Y320 HydrophobicContact CG-CE2 4.14Å; L315-Y320 WeakPolarHBondContact O-CE2 3.39Å; V317-Y320 PolarHBondContact O-N 2.66Å; V317-Y320 VanDerWaalsContact O-N 3.09Å; S318-Y320 PolarHBondContact O-N 2.99Å; Y320-N322 VanDerWaalsContact C-N 3.32Å; Y320-A324 WeakPolarHBondContact O-CB 3.43Å; Y320-A324 PolarHBondContact O-N 3.47Å; Y320-A324 VanDerWaalsContact O-N 3.11Å
321	L	89.9	Confident	82.5	Confident	1 Å²	1	48.7 Å²	48.7	1%	0.005	25%	0.25	C	C	.	.	H	α-helix	trans	-65.5	-40.9	175.2	-63.3	164.1	0	0	0	110.4	F230 V233 E234 V317 S318 A324 A325 Y429 V430	F230-L321 HydrophobicContact CD1-CB 4.4Å; F230-L321 HydrophobicContact CD1-CD2 4.18Å; F230-L321 WeakPolarHBondContact CE1-O 3.46Å; V233-L321 HydrophobicContact CB-CD2 4.17Å; V233-L321 HydrophobicContact CG1-CD2 3.84Å; E234-L321 HydrophobicContact CB-CD1 3.65Å; E234-L321 HydrophobicContact CB-CD2 4Å; E234-L321 HydrophobicContact CB-CG 4.37Å; E234-L321 HydrophobicContact CG-CD1 3.82Å; V317-L321 HydrophobicContact CG1-CD1 4.19Å; V317-L321 HydrophobicContact CG1-CG 4.36Å; V317-L321 WeakPolarHBondContact O-CG 3.49Å; V317-L321 PolarHBondContact O-N 2.92Å; S318-L321 PolarHBondContact O-N 3.33Å; L321-A324 PolarHBondContact O-N 2.91Å; L321-A324 VanDerWaalsContact O-N 3.16Å; L321-A325 PolarHBondContact O-N 3.5Å; L321-Y429 HydrophobicContact CD1-CE1 4.21Å; L321-V430 HydrophobicContact CB-CG2 4.31Å
322	N	90.5	Very high	84.8	Confident	0 Å²	0	37.8 Å²	37.8	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-55.9	-54	175.6	-152.7	89.5	0	0	0	111.7	S318 Y320 A324 A325 D326 D366 I369 V430	S318-N322 WeakPolarHBondContact O-CB 3.45Å; S318-N322 PolarHBondContact O-N 3.47Å; Y320-N322 VanDerWaalsContact C-N 3.32Å; N322-A324 PolarHBondContact O-N 2.99Å; N322-A325 WeakPolarHBondContact O-CB 3.35Å; N322-A325 PolarHBondContact O-N 3.37Å; N322-D326 VanDerWaalsContact O-CB 3.29Å; N322-D326 WeakPolarHBondContact O-CB 3.38Å; N322-D326 PolarHBondContact O-N 3Å; N322-D366 VanDerWaalsContact ND2-CB 3.29Å; N322-D366 WeakPolarHBondContact ND2-CB 3.45Å; N322-D366 PolarHBondContact ND2-OD1 3.28Å; N322-D366 PolarHBondContact OD1-OD1 3.48Å; N322-I369 HydrophobicContact CB-CG2 3.88Å; N322-I369 WeakPolarHBondContact OD1-CD1 3.49Å; N322-I369 VanDerWaalsContact OD1-CG2 3.25Å; N322-I369 WeakPolarHBondContact OD1-CG2 3.1Å; N322-V430 WeakPolarHBondContact OD1-CG1 3.29Å
323	L	91.8	Very high	86.7	Confident	26 Å²	26	34.9 Å²	34.9	14%	0.136	18%	0.177	C	C	.	.	H	α-helix	trans	-61.1	-29.3	178	-68	167.9	0	0	0	113.4	L315 G319 L327 L370 L383 T387	L315-L323 HydrophobicContact CD2-CD1 4.18Å; G319-L323 WeakPolarHBondContact O-CG 3.49Å; G319-L323 PolarHBondContact O-N 3.01Å; L323-L327 WeakPolarHBondContact O-CB 3.46Å; L323-L327 PolarHBondContact O-N 3.49Å; L323-L370 HydrophobicContact CD1-CD2 3.98Å; L323-L370 HydrophobicContact CD2-CD1 4.06Å; L323-L370 HydrophobicContact CD2-CD2 4.12Å; L323-L370 HydrophobicContact CG-CD2 3.91Å; L323-L383 HydrophobicContact CD1-CB 4.04Å; L323-L383 HydrophobicContact CD1-CD1 4.27Å; L323-L383 HydrophobicContact CD1-CD2 4.15Å; L323-L383 HydrophobicContact CD1-CG 4.38Å; L323-L383 HydrophobicContact CD2-CB 3.82Å; L323-T387 HydrophobicContact CD2-CG2 3.89Å
324	A	89.5	Confident	88.1	Confident	43 Å²	43	31.6 Å²	31.6	36%	0.355	16%	0.16	S	C	.	.	H	α-helix	trans	-76.2	-31.4	175.4	0	0	0	0	0	112.5	F230 Y320 L321 N322 A328	F230-A324 HydrophobicContact CE1-CB 4.37Å; F230-A324 HydrophobicContact CZ-CB 4.31Å; Y320-A324 WeakPolarHBondContact O-CB 3.43Å; Y320-A324 PolarHBondContact O-N 3.47Å; Y320-A324 VanDerWaalsContact O-N 3.11Å; L321-A324 PolarHBondContact O-N 2.91Å; L321-A324 VanDerWaalsContact O-N 3.16Å; N322-A324 PolarHBondContact O-N 2.99Å; A324-A328 WeakPolarHBondContact O-CB 3.28Å; A324-A328 PolarHBondContact O-N 3.19Å
325	A	88.8	Confident	88.8	Confident	3 Å²	3	25.2 Å²	25.2	3%	0.025	13%	0.126	C	C	.	.	H	α-helix	trans	-72.5	-54.5	174.5	0	0	0	0	0	110.7	F230 L321 N322 L327 A328 H329 F427 V430	F230-A325 HydrophobicContact CE1-CB 3.69Å; F230-A325 HydrophobicContact CZ-CB 3.89Å; L321-A325 PolarHBondContact O-N 3.5Å; N322-A325 WeakPolarHBondContact O-CB 3.35Å; N322-A325 PolarHBondContact O-N 3.37Å; A325-L327 PolarHBondContact O-N 3.16Å; A325-A328 WeakPolarHBondContact O-CA 3.42Å; A325-A328 WeakPolarHBondContact O-CB 3.26Å; A325-A328 PolarHBondContact O-N 3.02Å; A325-H329 PolarHBondContact O-N 3.27Å; A325-F427 HydrophobicContact CB-CD1 3.83Å; A325-F427 HydrophobicContact CB-CE1 3.85Å; A325-V430 HydrophobicContact CB-CG2 3.86Å
326	D	90.1	Very high	89	Confident	3 Å²	3	27 Å²	27	2%	0.016	14%	0.141	C	C	.	.	H	α-helix	trans	-50.8	-54.5	174.7	169.4	2.3	0	0	0	110.6	N322 A328 H329 N330 T387	N322-D326 VanDerWaalsContact O-CB 3.29Å; N322-D326 WeakPolarHBondContact O-CB 3.38Å; N322-D326 PolarHBondContact O-N 3Å; D326-A328 PolarHBondContact O-N 2.98Å; D326-A328 VanDerWaalsContact O-N 3.1Å; D326-H329 PolarHBondContact O-N 2.99Å; D326-N330 WeakPolarHBondContact O-CB 3.37Å; D326-N330 PolarHBondContact O-N 2.94Å; D326-N330 PolarHBondContact OD1-ND2 2.98Å; D326-T387 HydrophobicContact CB-CG2 4.14Å; D326-T387 VanDerWaalsContact CG-CB 3.49Å; D326-T387 WeakPolarHBondContact OD1-CB 3.37Å; D326-T387 PolarHBondContact OD1-OG1 3.32Å; D326-T387 WeakPolarHBondContact OD2-CB 3.41Å; D326-T387 WeakPolarHBondContact OD2-CG2 3.42Å; D326-T387 PolarHBondContact OD2-OG1 3.21Å
327	L	91.4	Very high	89.2	Confident	77 Å²	77	20.4 Å²	20.4	40%	0.403	12%	0.116	S	C	.	.	H	α-helix	trans	-58.5	-29.5	177.6	-177.4	144.9	0	0	0	113.9	L323 A325 F331 T387	L323-L327 WeakPolarHBondContact O-CB 3.46Å; L323-L327 PolarHBondContact O-N 3.49Å; A325-L327 PolarHBondContact O-N 3.16Å; L327-F331 VanDerWaalsContact O-CB 3.31Å; L327-F331 WeakPolarHBondContact O-CB 3.33Å; L327-F331 PolarHBondContact O-N 3.49Å; L327-T387 HydrophobicContact CB-CG2 3.96Å
328	A	86.6	Confident	89.4	Confident	20 Å²	20	19.4 Å²	19.4	17%	0.165	11%	0.11	C	C	.	.	H	α-helix	trans	-79.9	-31.9	176.3	0	0	0	0	0	112.9	A324 A325 D326 T332	A324-A328 WeakPolarHBondContact O-CB 3.28Å; A324-A328 PolarHBondContact O-N 3.19Å; A325-A328 WeakPolarHBondContact O-CA 3.42Å; A325-A328 WeakPolarHBondContact O-CB 3.26Å; A325-A328 PolarHBondContact O-N 3.02Å; D326-A328 PolarHBondContact O-N 2.98Å; D326-A328 VanDerWaalsContact O-N 3.1Å; A328-T332 PolarHBondContact O-N 3.09Å; A328-T332 PolarHBondContact O-OG1 2.87Å
329	H	89	Confident	89.3	Confident	2 Å²	2	19.1 Å²	19.1	1%	0.009	11%	0.109	C	C	.	.	H	α-helix	trans	-72	-53.2	173	-173.4	93.5	0	0	0	110.9	D183 A325 D326 F331 T332 D333 H358 E359 T423 F427	D183-H329 IonicContact OD1-CE1 3.88Å; D183-H329 IonicContact OD2-CE1 3.99Å; D183-H329 PolarHBondContact OD2-CE1 3.37Å; D183-H329 IonicContact OD2-ND1 3.14Å; D183-H329 PolarHBondContact OD2-ND1 3.47Å; A325-H329 PolarHBondContact O-N 3.27Å; D326-H329 PolarHBondContact O-N 2.99Å; H329-F331 PolarHBondContact O-N 2.95Å; H329-T332 WeakPolarHBondContact CA-OG1 3.16Å; H329-T332 WeakPolarHBondContact O-CA 2.85Å; H329-T332 PolarHBondContact O-N 2.9Å; H329-T332 PolarHBondContact O-OG1 2.88Å; H329-D333 IonicContact CD2-OD1 3.41Å; H329-D333 IonicContact CD2-OD2 3.45Å; H329-D333 PolarHBondContact CD2-OD2 2.81Å; H329-D333 IonicContact NE2-OD1 3.63Å; H329-D333 IonicContact NE2-OD2 3.27Å; H329-D333 PolarHBondContact O-N 3.13Å; H329-D333 VanDerWaalsContact O-OD2 3.13Å; H329-H358 AromaticContact NE2-CD2 3.99Å; H329-E359 IonicContact CD2-OE1 3.13Å; H329-E359 PolarHBondContact CD2-OE1 3.39Å; H329-E359 IonicContact NE2-OE1 3.66Å; H329-T423 HydrophobicContact CB-CG2 3.91Å; H329-F427 HydrophobicContact CB-CE1 3.74Å; H329-F427 HydrophobicContact CB-CE2 4.22Å; H329-F427 HydrophobicContact CB-CZ 3.36Å; H329-F427 AromaticContact CE1-CE2 3.71Å; H329-F427 AromaticContact CG-CE2 3.78Å; H329-F427 AromaticContact CG-CZ 3.35Å; H329-F427 AromaticContact ND1-CE2 3.23Å; H329-F427 WeakPolarHBondContact ND1-CE2 3.44Å; H329-F427 AromaticContact ND1-CZ 3.32Å; H329-F427 VanDerWaalsContact ND1-CZ 3.32Å; H329-F427 WeakPolarHBondContact ND1-CZ 3.29Å
330	N	90.8	Very high	89.1	Confident	1 Å²	1	19.5 Å²	19.5	1%	0.005	11%	0.112	C	C	.	.	H	α-helix	trans	-48.9	-41.1	171.5	-105.4	-81.9	0	0	0	111	D326 D333 G334 E359 A391	D326-N330 WeakPolarHBondContact O-CB 3.37Å; D326-N330 PolarHBondContact O-N 2.94Å; D326-N330 PolarHBondContact OD1-ND2 2.98Å; N330-D333 WeakPolarHBondContact CA-OD2 3.25Å; N330-D333 PolarHBondContact O-N 3.05Å; N330-G334 PolarHBondContact O-N 3.32Å; N330-E359 PolarHBondContact ND2-OE2 3.12Å; N330-A391 HydrophobicContact CB-CB 4.08Å; N330-A391 WeakPolarHBondContact O-CA 3.43Å; N330-A391 WeakPolarHBondContact O-CB 3.49Å; N330-A391 PolarHBondContact O-N 3.28Å; N330-A391 WeakPolarHBondContact OD1-CB 3.25Å
331	F	89.8	Confident	89.1	Confident	57 Å²	57	15.2 Å²	15.2	25%	0.25	10%	0.095	C	C	.	.	H	α-helix	trans	-62.5	-41.4	173.6	177.1	-97.9	0	0	0	114.1	L327 H329 D333 L335 G390 A393 G394 V419	L327-F331 VanDerWaalsContact O-CB 3.31Å; L327-F331 WeakPolarHBondContact O-CB 3.33Å; L327-F331 PolarHBondContact O-N 3.49Å; H329-F331 PolarHBondContact O-N 2.95Å; F331-D333 VanDerWaalsContact C-N 3.34Å; F331-L335 HydrophobicContact CD1-CD1 3.66Å; F331-L335 HydrophobicContact CE1-CD1 3.29Å; F331-L335 HydrophobicContact CE1-CG 4.24Å; F331-L335 HydrophobicContact CG-CD1 4.43Å; F331-L335 HydrophobicContact CZ-CD1 3.77Å; F331-L335 HydrophobicContact CZ-CD2 4.5Å; F331-L335 HydrophobicContact CZ-CG 4.3Å; F331-L335 WeakPolarHBondContact O-CD1 3.28Å; F331-L335 WeakPolarHBondContact O-CG 3.44Å; F331-L335 PolarHBondContact O-N 3.24Å; F331-L335 VanDerWaalsContact O-N 3.1Å; F331-G390 WeakPolarHBondContact CA-O 3.42Å; F331-G390 WeakPolarHBondContact CD2-O 3.36Å; F331-A393 HydrophobicContact CD2-CB 4.21Å; F331-A393 HydrophobicContact CE2-CB 4.37Å; F331-G394 WeakPolarHBondContact O-CA 3.21Å; F331-V419 HydrophobicContact CD1-CG1 4.27Å; F331-V419 HydrophobicContact CE1-CG1 4.37Å
332	T	86.9	Confident	88.9	Confident	5 Å²	5	19.5 Å²	19.5	3%	0.031	11%	0.112	C	C	.	.	H	α-helix	trans	-66.4	-34.1	173.5	41	0	0	0	0	112.8	A328 H329 L335 A336 V419 L420	A328-T332 PolarHBondContact O-N 3.09Å; A328-T332 PolarHBondContact O-OG1 2.87Å; H329-T332 WeakPolarHBondContact CA-OG1 3.16Å; H329-T332 WeakPolarHBondContact O-CA 2.85Å; H329-T332 PolarHBondContact O-N 2.9Å; H329-T332 PolarHBondContact O-OG1 2.88Å; T332-L335 WeakPolarHBondContact O-CB 3.46Å; T332-L335 PolarHBondContact O-N 3.36Å; T332-A336 PolarHBondContact O-N 3.22Å; T332-V419 HydrophobicContact CG2-CB 4.12Å; T332-V419 HydrophobicContact CG2-CG1 3.39Å; T332-L420 HydrophobicContact CG2-CD2 3.91Å
333	D	89.7	Confident	88.4	Confident	6 Å²	6	21.8 Å²	21.8	3%	0.032	14%	0.135	C	C	.	.	H	α-helix	trans	-70.6	-41.7	178.5	-48.6	-30.5	0	0	0	111.4	I145 H329 N330 F331 L335 A336 I337 V355	I145-D333 HydrophobicContact CD1-CB 4.29Å; H329-D333 IonicContact CD2-OD1 3.41Å; H329-D333 IonicContact CD2-OD2 3.45Å; H329-D333 PolarHBondContact CD2-OD2 2.81Å; H329-D333 IonicContact NE2-OD1 3.63Å; H329-D333 IonicContact NE2-OD2 3.27Å; H329-D333 PolarHBondContact O-N 3.13Å; H329-D333 VanDerWaalsContact O-OD2 3.13Å; N330-D333 WeakPolarHBondContact CA-OD2 3.25Å; N330-D333 PolarHBondContact O-N 3.05Å; F331-D333 VanDerWaalsContact C-N 3.34Å; D333-L335 VanDerWaalsContact C-N 3.29Å; D333-L335 PolarHBondContact O-N 2.97Å; D333-A336 PolarHBondContact O-N 3.21Å; D333-A336 VanDerWaalsContact O-N 3.16Å; D333-I337 WeakPolarHBondContact O-CB 3.45Å; D333-I337 WeakPolarHBondContact O-CG1 3.29Å; D333-I337 PolarHBondContact O-N 3.43Å; D333-V355 HydrophobicContact CB-CG1 3.78Å; D333-V355 HydrophobicContact CB-CG2 4.31Å
334	G	91.5	Very high	88	Confident	0 Å²	0	21.4 Å²	21.4	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-57.4	-43.7	171.4	0	0	0	0	0	112	N330 A336 I337 G338 A391 G394 T395	N330-G334 PolarHBondContact O-N 3.32Å; G334-A336 PolarHBondContact O-N 3.4Å; G334-I337 PolarHBondContact O-N 3.1Å; G334-G338 PolarHBondContact O-N 3.47Å; G334-A391 WeakPolarHBondContact CA-O 3.32Å; G334-G394 VanDerWaalsContact C-C 3.47Å; G334-T395 VanDerWaalsContact C-N 3.27Å; G334-T395 WeakPolarHBondContact CA-OG1 3.35Å; G334-T395 WeakPolarHBondContact O-CA 3.48Å; G334-T395 PolarHBondContact O-N 3.04Å; G334-T395 PolarHBondContact O-OG1 3.09Å
335	L	88.1	Confident	88	Confident	2 Å²	2	24.3 Å²	24.3	1%	0.01	14%	0.139	C	C	.	.	H	α-helix	trans	-59.3	-46.5	173.8	-73.8	159.2	0	0	0	111.5	F331 T332 D333 G338 A339 G394 C397 A398 V406 I410	F331-L335 HydrophobicContact CD1-CD1 3.66Å; F331-L335 HydrophobicContact CE1-CD1 3.29Å; F331-L335 HydrophobicContact CE1-CG 4.24Å; F331-L335 HydrophobicContact CG-CD1 4.43Å; F331-L335 HydrophobicContact CZ-CD1 3.77Å; F331-L335 HydrophobicContact CZ-CD2 4.5Å; F331-L335 HydrophobicContact CZ-CG 4.3Å; F331-L335 WeakPolarHBondContact O-CD1 3.28Å; F331-L335 WeakPolarHBondContact O-CG 3.44Å; F331-L335 PolarHBondContact O-N 3.24Å; F331-L335 VanDerWaalsContact O-N 3.1Å; T332-L335 WeakPolarHBondContact O-CB 3.46Å; T332-L335 PolarHBondContact O-N 3.36Å; D333-L335 VanDerWaalsContact C-N 3.29Å; D333-L335 PolarHBondContact O-N 2.97Å; L335-G338 PolarHBondContact O-N 2.77Å; L335-A339 VanDerWaalsContact O-CB 3.24Å; L335-A339 WeakPolarHBondContact O-CB 3.34Å; L335-A339 PolarHBondContact O-N 3.14Å; L335-G394 WeakPolarHBondContact CD2-O 3.16Å; L335-C397 HydrophobicContact CD2-CB 3.95Å; L335-A398 HydrophobicContact CD2-CB 4.21Å; L335-A398 WeakPolarHBondContact O-CB 3.45Å; L335-V406 HydrophobicContact CD2-CG1 3.84Å; L335-I410 HydrophobicContact CB-CD1 4.3Å; L335-I410 HydrophobicContact CD1-CD1 3.56Å; L335-I410 HydrophobicContact CD2-CD1 4.1Å; L335-I410 HydrophobicContact CG-CD1 4.2Å
336	A	86.3	Confident	88	Confident	40 Å²	40	26.9 Å²	26.9	33%	0.331	17%	0.166	S	C	.	.	H	α-helix	trans	-63.2	-42.8	178.2	0	0	0	0	0	112.5	T332 D333 G334 A339 S340 T351	T332-A336 PolarHBondContact O-N 3.22Å; D333-A336 PolarHBondContact O-N 3.21Å; D333-A336 VanDerWaalsContact O-N 3.16Å; G334-A336 PolarHBondContact O-N 3.4Å; A336-A339 PolarHBondContact O-N 3.25Å; A336-S340 VanDerWaalsContact O-CB 3.23Å; A336-S340 WeakPolarHBondContact O-CB 3.35Å; A336-S340 PolarHBondContact O-N 3.35Å; A336-S340 PolarHBondContact O-OG 2.82Å; A336-T351 HydrophobicContact CB-CG2 4.1Å
337	I	90.9	Very high	87.8	Confident	0 Å²	0	30.9 Å²	30.9	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-64.4	-47.3	175.6	-72	175.7	0	0	0	110.9	A141 I145 D333 G334 A339 S340 F341 T351 V355	A141-I337 HydrophobicContact CB-CG2 3.89Å; I145-I337 HydrophobicContact CD1-CD1 3.6Å; I145-I337 HydrophobicContact CG1-CD1 4.15Å; I145-I337 HydrophobicContact CG2-CD1 4.08Å; D333-I337 WeakPolarHBondContact O-CB 3.45Å; D333-I337 WeakPolarHBondContact O-CG1 3.29Å; D333-I337 PolarHBondContact O-N 3.43Å; G334-I337 PolarHBondContact O-N 3.1Å; I337-A339 VanDerWaalsContact C-N 3.32Å; I337-A339 PolarHBondContact O-N 2.97Å; I337-S340 WeakPolarHBondContact CA-OG 3.32Å; I337-S340 PolarHBondContact O-N 3.37Å; I337-S340 PolarHBondContact O-OG 2.9Å; I337-F341 HydrophobicContact CG2-CD2 3.86Å; I337-F341 HydrophobicContact CG2-CE2 4Å; I337-F341 WeakPolarHBondContact O-CD2 3.24Å; I337-F341 PolarHBondContact O-N 2.81Å; I337-F341 VanDerWaalsContact O-N 3.09Å; I337-T351 HydrophobicContact CG1-CG2 4.32Å; I337-V355 HydrophobicContact CD1-CB 4.48Å; I337-V355 HydrophobicContact CD1-CG1 4.39Å
338	G	89.3	Confident	87.6	Confident	0 Å²	0	27.2 Å²	27.2	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-62.9	-37.4	177.3	0	0	0	0	0	113	G334 L335 R342	G334-G338 PolarHBondContact O-N 3.47Å; L335-G338 PolarHBondContact O-N 2.77Å; G338-R342 PolarHBondContact O-N 3.23Å
339	A	85.1	Confident	87.9	Confident	16 Å²	16	30.2 Å²	30.2	13%	0.132	18%	0.18	C	C	.	.	H	α-helix	trans	-67.9	-50.5	175.9	0	0	0	0	0	112.3	L335 A336 I337 F341 R342 G343	L335-A339 VanDerWaalsContact O-CB 3.24Å; L335-A339 WeakPolarHBondContact O-CB 3.34Å; L335-A339 PolarHBondContact O-N 3.14Å; A336-A339 PolarHBondContact O-N 3.25Å; I337-A339 VanDerWaalsContact C-N 3.32Å; I337-A339 PolarHBondContact O-N 2.97Å; A339-F341 PolarHBondContact O-N 3.43Å; A339-R342 WeakPolarHBondContact O-CA 3.24Å; A339-R342 WeakPolarHBondContact O-CB 3.45Å; A339-R342 PolarHBondContact O-N 3.3Å; A339-R342 VanDerWaalsContact O-N 3.07Å; A339-G343 PolarHBondContact O-N 3.3Å
340	S	85.7	Confident	87.9	Confident	8 Å²	8	35 Å²	35	6%	0.056	21%	0.205	C	C	.	.	H	α-helix	trans	-63.8	-41.4	-176.3	52.5	0	0	0	0	112.6	A336 I337 R342 G343 G344 G348 T351	A336-S340 VanDerWaalsContact O-CB 3.23Å; A336-S340 WeakPolarHBondContact O-CB 3.35Å; A336-S340 PolarHBondContact O-N 3.35Å; A336-S340 PolarHBondContact O-OG 2.82Å; I337-S340 WeakPolarHBondContact CA-OG 3.32Å; I337-S340 PolarHBondContact O-N 3.37Å; I337-S340 PolarHBondContact O-OG 2.9Å; S340-R342 VanDerWaalsContact C-N 3.27Å; S340-R342 PolarHBondContact O-N 2.89Å; S340-G343 CarbonylContact O-C 3.35Å; S340-G343 WeakPolarHBondContact O-CA 3.46Å; S340-G343 PolarHBondContact O-N 2.9Å; S340-G343 VanDerWaalsContact O-N 3.12Å; S340-G344 PolarHBondContact O-N 3.4Å; S340-G348 PolarHBondContact O-N 3.46Å; S340-T351 WeakPolarHBondContact CB-OG1 3.49Å; S340-T351 WeakPolarHBondContact OG-CB 3.47Å; S340-T351 PolarHBondContact OG-OG1 3.09Å
341	F	89.7	Confident	87.8	Confident	9 Å²	9	36.4 Å²	36.4	4%	0.039	21%	0.213	C	C	.	.	H	α-helix	trans	-62.9	-32.4	172.6	-88.8	-71	0	0	0	113	L129 L134 Y137 A138 A141 I337 A339 G344 G348 I349 T352	L129-F341 HydrophobicContact CD1-CD1 4.49Å; L134-F341 HydrophobicContact CD1-CB 3.87Å; L134-F341 WeakPolarHBondContact CD1-O 3.46Å; Y137-F341 HydrophobicContact CD2-CE1 4.33Å; Y137-F341 HydrophobicContact CG-CE1 4.4Å; A138-F341 HydrophobicContact CB-CB 4.11Å; A138-F341 HydrophobicContact CB-CD2 3.97Å; A138-F341 HydrophobicContact CB-CG 4.2Å; A141-F341 HydrophobicContact CB-CE2 3.53Å; A141-F341 HydrophobicContact CB-CZ 4.08Å; I337-F341 HydrophobicContact CG2-CD2 3.86Å; I337-F341 HydrophobicContact CG2-CE2 4Å; I337-F341 WeakPolarHBondContact O-CD2 3.24Å; I337-F341 PolarHBondContact O-N 2.81Å; I337-F341 VanDerWaalsContact O-N 3.09Å; A339-F341 PolarHBondContact O-N 3.43Å; F341-G344 CarbonylContact O-C 3.6Å; F341-G344 WeakPolarHBondContact O-CA 3.46Å; F341-G344 PolarHBondContact O-N 3.41Å; F341-G348 WeakPolarHBondContact CE2-O 3.44Å; F341-G348 VanDerWaalsContact CZ-C 3.47Å; F341-I349 HydrophobicContact CE1-CG1 4.23Å; F341-I349 HydrophobicContact CZ-CG1 4.22Å; F341-T352 WeakPolarHBondContact CE2-OG1 3.23Å
342	R	85.9	Confident	87.9	Confident	92 Å²	92	33.9 Å²	33.9	35%	0.347	20%	0.203	S	C	.	.	H	α-helix	trans	-71.3	-32.4	173.5	-157.2	-173.1	-165.1	111.1	3.3	112.3	L134 G338 A339 S340 G344 L399 T401 G404	L134-R342 HydrophobicContact CD2-CG 4.4Å; G338-R342 PolarHBondContact O-N 3.23Å; A339-R342 WeakPolarHBondContact O-CA 3.24Å; A339-R342 WeakPolarHBondContact O-CB 3.45Å; A339-R342 PolarHBondContact O-N 3.3Å; A339-R342 VanDerWaalsContact O-N 3.07Å; S340-R342 VanDerWaalsContact C-N 3.27Å; S340-R342 PolarHBondContact O-N 2.89Å; R342-G344 VanDerWaalsContact C-N 3.25Å; R342-L399 PolarHBondContact NH1-O 3.01Å; R342-T401 VanDerWaalsContact CZ-O 3.23Å; R342-T401 PolarHBondContact NH1-O 3.31Å; R342-T401 PolarHBondContact NH2-O 2.9Å; R342-G404 VanDerWaalsContact CD-CA 3.47Å
343	G	79.2	Confident	88.1	Confident	47 Å²	47	38.1 Å²	38.1	49%	0.485	22%	0.223	S	C	.	.	H	α-helix	trans	-68.6	-22.8	169	0	0	0	0	0	113.7	A339 S340	A339-G343 PolarHBondContact O-N 3.3Å; S340-G343 CarbonylContact O-C 3.35Å; S340-G343 WeakPolarHBondContact O-CA 3.46Å; S340-G343 PolarHBondContact O-N 2.9Å; S340-G343 VanDerWaalsContact O-N 3.12Å
344	G	83.9	Confident	88	Confident	18 Å²	18	38.8 Å²	38.8	19%	0.186	23%	0.228	C	C	.	.			trans	144.6	155.5	167.3	0	0	0	0	0	112.7	S340 F341 R342 G346 L347 G348	S340-G344 PolarHBondContact O-N 3.4Å; F341-G344 CarbonylContact O-C 3.6Å; F341-G344 WeakPolarHBondContact O-CA 3.46Å; F341-G344 PolarHBondContact O-N 3.41Å; R342-G344 VanDerWaalsContact C-N 3.25Å; G344-G346 VanDerWaalsContact C-N 3.26Å; G344-G346 PolarHBondContact O-N 3.13Å; G344-G346 VanDerWaalsContact O-N 3.09Å; G344-L347 PolarHBondContact O-N 2.8Å; G344-G348 PolarHBondContact O-N 3.05Å
345	R	90.2	Very high	87.9	Confident	104 Å²	104	39 Å²	39	39%	0.392	23%	0.229	S	C	.	.	H	α-helix	trans	-49.1	-41.8	-176.1	-176	179	61.3	166.8	-6.1	114.5	L129 Y137 I349	L129-R345 HydrophobicContact CD1-CB 4.16Å; L129-R345 HydrophobicContact CD2-CB 4.34Å; Y137-R345 HydrophobicContact CD2-CG 4.28Å; Y137-R345 HydrophobicContact CE2-CG 4.14Å; R345-I349 HydrophobicContact CG-CD1 3.87Å; R345-I349 VanDerWaalsContact O-CG1 3.29Å; R345-I349 WeakPolarHBondContact O-CG1 3.46Å; R345-I349 PolarHBondContact O-N 3.01Å
346	G	88.6	Confident	88	Confident	57 Å²	57	40.7 Å²	40.7	59%	0.588	24%	0.238	S	C	*	.	H	α-helix	trans	-66.6	-40.9	-179	0	0	0	0	0	112.9	G344 L350	G344-G346 VanDerWaalsContact C-N 3.26Å; G344-G346 PolarHBondContact O-N 3.13Å; G344-G346 VanDerWaalsContact O-N 3.09Å; G346-L350 PolarHBondContact O-N 3.02Å; G346-L350 VanDerWaalsContact O-N 3.09Å
347	L	84.5	Confident	88.1	Confident	88 Å²	88	42 Å²	42	46%	0.461	24%	0.239	S	C	.	.	H	α-helix	trans	-67.7	-46.6	176.3	-175	64	0	0	0	110.4	G344 I349 L350 T351	G344-L347 PolarHBondContact O-N 2.8Å; L347-I349 VanDerWaalsContact C-N 3.34Å; L347-I349 PolarHBondContact O-N 3.1Å; L347-L350 WeakPolarHBondContact O-CB 3.4Å; L347-L350 PolarHBondContact O-N 3.03Å; L347-L350 VanDerWaalsContact O-N 3.1Å; L347-T351 PolarHBondContact O-N 3.11Å; L347-T351 PolarHBondContact O-OG1 3.27Å
348	G	89.2	Confident	87.9	Confident	0 Å²	0	42 Å²	42	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-55.6	-43.8	175.2	0	0	0	0	0	114	S340 F341 G344 T352	S340-G348 PolarHBondContact O-N 3.46Å; F341-G348 WeakPolarHBondContact CE2-O 3.44Å; F341-G348 VanDerWaalsContact CZ-C 3.47Å; G344-G348 PolarHBondContact O-N 3.05Å; G348-T352 WeakPolarHBondContact O-CB 3.42Å; G348-T352 PolarHBondContact O-N 3.1Å; G348-T352 PolarHBondContact O-OG1 3.09Å
349	I	92.8	Very high	87.9	Confident	83 Å²	83	42.1 Å²	42.1	43%	0.426	24%	0.24	S	C	.	.	H	α-helix	trans	-65	-42.2	175.3	-68.6	167.1	0	0	0	111.2	F341 R345 L347 T352 M353	F341-I349 HydrophobicContact CE1-CG1 4.23Å; F341-I349 HydrophobicContact CZ-CG1 4.22Å; R345-I349 HydrophobicContact CG-CD1 3.87Å; R345-I349 VanDerWaalsContact O-CG1 3.29Å; R345-I349 WeakPolarHBondContact O-CG1 3.46Å; R345-I349 PolarHBondContact O-N 3.01Å; L347-I349 VanDerWaalsContact C-N 3.34Å; L347-I349 PolarHBondContact O-N 3.1Å; I349-T352 PolarHBondContact O-N 2.86Å; I349-M353 VanDerWaalsContact O-CG 3.28Å; I349-M353 WeakPolarHBondContact O-CG 3.1Å; I349-M353 PolarHBondContact O-N 2.92Å
350	L	89.1	Confident	87.9	Confident	102 Å²	102	42.9 Å²	42.9	53%	0.534	24%	0.243	S	C	.	.	H	α-helix	trans	-61.5	-53.1	178	-179.3	60.8	0	0	0	111	G346 L347 T352 M353 T354	G346-L350 PolarHBondContact O-N 3.02Å; G346-L350 VanDerWaalsContact O-N 3.09Å; L347-L350 WeakPolarHBondContact O-CB 3.4Å; L347-L350 PolarHBondContact O-N 3.03Å; L347-L350 VanDerWaalsContact O-N 3.1Å; L350-T352 VanDerWaalsContact C-N 3.29Å; L350-T352 PolarHBondContact O-N 2.92Å; L350-M353 PolarHBondContact O-N 3.23Å; L350-T354 PolarHBondContact O-N 3.05Å; L350-T354 PolarHBondContact O-OG1 3.16Å
351	T	88.3	Confident	87.8	Confident	30 Å²	30	43 Å²	43	18%	0.184	24%	0.243	C	C	.	.	H	α-helix	trans	-57.5	-40.1	176.6	-57.3	0	0	0	0	111.9	A336 I337 S340 L347 M353 T354 V355	A336-T351 HydrophobicContact CB-CG2 4.1Å; I337-T351 HydrophobicContact CG1-CG2 4.32Å; S340-T351 WeakPolarHBondContact CB-OG1 3.49Å; S340-T351 WeakPolarHBondContact OG-CB 3.47Å; S340-T351 PolarHBondContact OG-OG1 3.09Å; L347-T351 PolarHBondContact O-N 3.11Å; L347-T351 PolarHBondContact O-OG1 3.27Å; T351-M353 VanDerWaalsContact C-N 3.32Å; T351-M353 PolarHBondContact O-N 3.04Å; T351-T354 PolarHBondContact O-N 3.39Å; T351-V355 HydrophobicContact CG2-CG2 4.33Å; T351-V355 WeakPolarHBondContact O-CB 3.49Å; T351-V355 VanDerWaalsContact O-CG2 3.3Å; T351-V355 WeakPolarHBondContact O-CG2 3.38Å; T351-V355 PolarHBondContact O-N 3.18Å
352	T	91.9	Very high	87.7	Confident	5 Å²	5	43 Å²	43	3%	0.031	24%	0.243	C	C	.	.	H	α-helix	trans	-60.5	-40.7	174.8	-55.1	0	0	0	0	112.1	A141 I145 F341 G348 I349 L350 L356	A141-T352 HydrophobicContact CB-CG2 3.64Å; A141-T352 VanDerWaalsContact CB-OG1 3.32Å; A141-T352 WeakPolarHBondContact CB-OG1 3.09Å; I145-T352 HydrophobicContact CG2-CG2 4.05Å; F341-T352 WeakPolarHBondContact CE2-OG1 3.23Å; G348-T352 WeakPolarHBondContact O-CB 3.42Å; G348-T352 PolarHBondContact O-N 3.1Å; G348-T352 PolarHBondContact O-OG1 3.09Å; I349-T352 PolarHBondContact O-N 2.86Å; L350-T352 VanDerWaalsContact C-N 3.29Å; L350-T352 PolarHBondContact O-N 2.92Å; T352-L356 WeakPolarHBondContact O-CB 3.1Å; T352-L356 PolarHBondContact O-N 2.88Å
353	M	90.6	Very high	87.8	Confident	93 Å²	93	38.9 Å²	38.9	46%	0.458	23%	0.228	S	C	.	.	H	α-helix	trans	-73.1	-38.6	179.8	-66.9	-69	151.8	0	0	111.9	I349 L350 T351 L356 L357	I349-M353 VanDerWaalsContact O-CG 3.28Å; I349-M353 WeakPolarHBondContact O-CG 3.1Å; I349-M353 PolarHBondContact O-N 2.92Å; L350-M353 PolarHBondContact O-N 3.23Å; T351-M353 VanDerWaalsContact C-N 3.32Å; T351-M353 PolarHBondContact O-N 3.04Å; M353-L356 HydrophobicContact SD-CD2 4.49Å; M353-L357 VanDerWaalsContact O-CG 3.26Å; M353-L357 WeakPolarHBondContact O-CG 3.1Å; M353-L357 PolarHBondContact O-N 2.91Å
354	T	86.9	Confident	88.2	Confident	21 Å²	21	36.7 Å²	36.7	13%	0.129	21%	0.205	C	C	.	.	H	α-helix	trans	-57.2	-55.3	170.8	-67.6	0	0	0	0	111	L350 T351 L356 L357 H358 E469	L350-T354 PolarHBondContact O-N 3.05Å; L350-T354 PolarHBondContact O-OG1 3.16Å; T351-T354 PolarHBondContact O-N 3.39Å; T354-L356 VanDerWaalsContact C-N 3.35Å; T354-L356 PolarHBondContact O-N 2.65Å; T354-L357 WeakPolarHBondContact O-CB 3.32Å; T354-L357 PolarHBondContact O-N 2.87Å; T354-H358 PolarHBondContact O-N 2.94Å; T354-E469 HydrophobicContact CG2-CG 3.4Å; T354-E469 WeakPolarHBondContact CG2-OE1 3.07Å
355	V	90	Very high	88.4	Confident	5 Å²	5	35.9 Å²	35.9	3%	0.03	20%	0.197	C	C	.	.	H	α-helix	trans	-59.6	-46.2	-178.9	169.5	0	0	0	0	111.2	I145 D333 I337 T351 L357 H358 E359	I145-V355 HydrophobicContact CB-CG1 4.36Å; I145-V355 HydrophobicContact CD1-CG1 3.61Å; I145-V355 HydrophobicContact CG2-CB 4.49Å; I145-V355 HydrophobicContact CG2-CG1 4.07Å; D333-V355 HydrophobicContact CB-CG1 3.78Å; D333-V355 HydrophobicContact CB-CG2 4.31Å; I337-V355 HydrophobicContact CD1-CB 4.48Å; I337-V355 HydrophobicContact CD1-CG1 4.39Å; T351-V355 HydrophobicContact CG2-CG2 4.33Å; T351-V355 WeakPolarHBondContact O-CB 3.49Å; T351-V355 VanDerWaalsContact O-CG2 3.3Å; T351-V355 WeakPolarHBondContact O-CG2 3.38Å; T351-V355 PolarHBondContact O-N 3.18Å; V355-L357 PolarHBondContact O-N 2.8Å; V355-L357 VanDerWaalsContact O-N 3.07Å; V355-H358 WeakPolarHBondContact CA-NE2 3.42Å; V355-H358 PolarHBondContact O-CD2 3.41Å; V355-H358 PolarHBondContact O-N 2.87Å; V355-H358 VanDerWaalsContact O-N 3.09Å; V355-E359 HydrophobicContact CG1-CG 3.75Å; V355-E359 WeakPolarHBondContact O-CB 3.32Å; V355-E359 PolarHBondContact O-N 2.97Å
356	L	90.6	Very high	88.4	Confident	36 Å²	36	31.1 Å²	31.1	19%	0.188	18%	0.179	C	C	.	.	H	α-helix	trans	-55	-30	176.3	-178.8	61.9	0	0	0	113.5	I145 A148 T352 M353 T354 V360	I145-L356 HydrophobicContact CG2-CB 4.18Å; A148-L356 HydrophobicContact CB-CD1 3.44Å; A148-L356 VanDerWaalsContact CB-CD1 3.44Å; T352-L356 WeakPolarHBondContact O-CB 3.1Å; T352-L356 PolarHBondContact O-N 2.88Å; M353-L356 HydrophobicContact SD-CD2 4.49Å; T354-L356 VanDerWaalsContact C-N 3.35Å; T354-L356 PolarHBondContact O-N 2.65Å; L356-V360 HydrophobicContact CD1-CG2 4.2Å
357	L	87.2	Confident	88.5	Confident	68 Å²	68	28.5 Å²	28.5	36%	0.356	15%	0.152	S	C	.	.	H	α-helix	trans	-77.1	-31.4	179.7	-72.6	166.7	0	0	0	113.3	M353 T354 V355 P361 I465 L468	M353-L357 VanDerWaalsContact O-CG 3.26Å; M353-L357 WeakPolarHBondContact O-CG 3.1Å; M353-L357 PolarHBondContact O-N 2.91Å; T354-L357 WeakPolarHBondContact O-CB 3.32Å; T354-L357 PolarHBondContact O-N 2.87Å; V355-L357 PolarHBondContact O-N 2.8Å; V355-L357 VanDerWaalsContact O-N 3.07Å; L357-P361 WeakPolarHBondContact O-CD 3.3Å; L357-P361 VanDerWaalsContact O-CG 3.29Å; L357-P361 WeakPolarHBondContact O-CG 3.37Å; L357-I465 HydrophobicContact CB-CD1 4.39Å; L357-I465 HydrophobicContact CB-CG1 4.5Å; L357-I465 WeakPolarHBondContact O-CD1 3.19Å; L357-L468 HydrophobicContact CD1-CD1 4.02Å
358	H	87.7	Confident	88.7	Confident	1 Å²	1	24.3 Å²	24.3	1%	0.005	13%	0.13	C	C	.	.	H	α-helix	trans	-87.7	-33	172.5	53	-130.9	0	0	0	112.8	H187 H329 T354 V355 V360 P361 H362 M462 I465 E469	H187-H358 AromaticContact NE2-CE1 3.96Å; H329-H358 AromaticContact NE2-CD2 3.99Å; T354-H358 PolarHBondContact O-N 2.94Å; V355-H358 WeakPolarHBondContact CA-NE2 3.42Å; V355-H358 PolarHBondContact O-CD2 3.41Å; V355-H358 PolarHBondContact O-N 2.87Å; V355-H358 VanDerWaalsContact O-N 3.09Å; H358-V360 PolarHBondContact O-N 3.17Å; H358-P361 WeakPolarHBondContact O-CB 3.31Å; H358-P361 WeakPolarHBondContact O-CD 3.44Å; H358-H362 PolarHBondContact O-CD2 3.49Å; H358-H362 PolarHBondContact O-N 3.33Å; H358-M462 HydrophobicContact CB-CE 4Å; H358-M462 HydrophobicContact CB-SD 4.2Å; H358-I465 HydrophobicContact CB-CD1 3.76Å; H358-I465 HydrophobicContact CB-CG2 4.36Å; H358-E469 IonicContact ND1-OE1 3.4Å
359	E	88	Confident	88.7	Confident	2 Å²	2	24.5 Å²	24.5	1%	0.009	13%	0.131	C	C	.	.	H	α-helix	trans	-63.9	-43.4	-178.5	-85.3	-61.8	92.6	0	0	113.7	H329 N330 V355 H362 E363	H329-E359 IonicContact CD2-OE1 3.13Å; H329-E359 PolarHBondContact CD2-OE1 3.39Å; H329-E359 IonicContact NE2-OE1 3.66Å; N330-E359 PolarHBondContact ND2-OE2 3.12Å; V355-E359 HydrophobicContact CG1-CG 3.75Å; V355-E359 WeakPolarHBondContact O-CB 3.32Å; V355-E359 PolarHBondContact O-N 2.97Å; E359-H362 PolarHBondContact O-N 3.26Å; E359-E363 VanDerWaalsContact O-CB 3.28Å; E359-E363 WeakPolarHBondContact O-CB 3.42Å; E359-E363 WeakPolarHBondContact O-CG 3.39Å; E359-E363 PolarHBondContact O-N 2.89Å
360	V	85.8	Confident	88.7	Confident	32 Å²	32	20.5 Å²	20.5	19%	0.194	11%	0.11	C	C	.	.	H	α-helix	trans	-56.9	-46.4	177.4	165.8	0	0	0	0	111.9	P149 V152 L356 H358 V364	P149-V360 HydrophobicContact CG-CG2 4.08Å; V152-V360 HydrophobicContact CB-CG1 4.39Å; V152-V360 HydrophobicContact CG1-CG1 4.25Å; V152-V360 HydrophobicContact CG2-CG1 3.89Å; L356-V360 HydrophobicContact CD1-CG2 4.2Å; H358-V360 PolarHBondContact O-N 3.17Å; V360-V364 VanDerWaalsContact O-CG2 3.27Å; V360-V364 WeakPolarHBondContact O-CG2 3.5Å; V360-V364 PolarHBondContact O-N 3.19Å
361	P	82.8	Confident	88.7	Confident	11 Å²	11	16.8 Å²	16.8	7%	0.071	9%	0.092	C	C	.	.	H	α-helix	trans	-59.4	-46.9	168.1	-28.1	32.5	0	0	0	116.5	F175 L357 H358 V364 G365 M461	F175-P361 HydrophobicContact CE1-CB 4.11Å; F175-P361 HydrophobicContact CZ-CB 4.27Å; L357-P361 WeakPolarHBondContact O-CD 3.3Å; L357-P361 VanDerWaalsContact O-CG 3.29Å; L357-P361 WeakPolarHBondContact O-CG 3.37Å; H358-P361 WeakPolarHBondContact O-CB 3.31Å; H358-P361 WeakPolarHBondContact O-CD 3.44Å; P361-V364 PolarHBondContact O-N 3Å; P361-G365 PolarHBondContact O-N 2.89Å; P361-G365 VanDerWaalsContact O-N 3.11Å; P361-M461 HydrophobicContact CB-CE 3.53Å; P361-M461 HydrophobicContact CB-SD 3.27Å; P361-M461 WeakPolarHBondContact CB-SD 3.39Å; P361-M461 HydrophobicContact CG-CE 3.73Å; P361-M461 HydrophobicContact CG-SD 3.13Å; P361-M461 WeakPolarHBondContact CG-SD 3.37Å
362	H	87.8	Confident	88.7	Confident	8 Å²	8	17.4 Å²	17.4	4%	0.037	9%	0.093	C	C	.	.	H	α-helix	trans	-60.8	-48.9	-179.3	-82.7	-69.9	0	0	0	110.8	H358 E359 V364 G365 D366 F427	H358-H362 PolarHBondContact O-CD2 3.49Å; H358-H362 PolarHBondContact O-N 3.33Å; E359-H362 PolarHBondContact O-N 3.26Å; H362-V364 VanDerWaalsContact C-N 3.31Å; H362-V364 PolarHBondContact O-N 3.32Å; H362-G365 CarbonylContact O-C 3.56Å; H362-G365 WeakPolarHBondContact O-CA 3.3Å; H362-G365 PolarHBondContact O-N 3.15Å; H362-D366 PolarHBondContact O-N 3.44Å; H362-F427 AromaticContact CE1-CE2 3.79Å
363	E	89.3	Confident	88.5	Confident	6 Å²	6	17.3 Å²	17.3	3%	0.028	9%	0.092	C	C	.	.	H	α-helix	trans	-62.8	-32	177.7	-77.2	-90.9	-122.4	0	0	113.5	P149 E359 G365 F367 Q384	P149-E363 HydrophobicContact CB-CB 3.49Å; P149-E363 VanDerWaalsContact CB-CB 3.49Å; P149-E363 HydrophobicContact CB-CG 3.69Å; P149-E363 HydrophobicContact CG-CB 4.04Å; P149-E363 HydrophobicContact CG-CG 3.79Å; E359-E363 VanDerWaalsContact O-CB 3.28Å; E359-E363 WeakPolarHBondContact O-CB 3.42Å; E359-E363 WeakPolarHBondContact O-CG 3.39Å; E359-E363 PolarHBondContact O-N 2.89Å; E363-G365 VanDerWaalsContact C-N 3.33Å; E363-F367 WeakPolarHBondContact O-CB 3.4Å; E363-F367 PolarHBondContact O-N 3Å; E363-Q384 PolarHBondContact O-NE2 3.44Å; E363-Q384 VanDerWaalsContact OE2-CB 3.25Å; E363-Q384 WeakPolarHBondContact OE2-CB 3.47Å; E363-Q384 WeakPolarHBondContact OE2-CG 3.13Å; E363-Q384 PolarHBondContact OE2-NE2 3.29Å
364	V	86.9	Confident	88.4	Confident	1 Å²	1	15.5 Å²	15.5	1%	0.006	10%	0.098	C	C	.	.	H	α-helix	trans	-64.6	-40.3	169.5	164	0	0	0	0	111.4	W18 V152 L153 I156 L172 V360 P361 H362 A368	W18-V364 HydrophobicContact CH2-CG1 3.75Å; W18-V364 HydrophobicContact CH2-CG2 4.18Å; W18-V364 HydrophobicContact CZ2-CB 4.42Å; W18-V364 HydrophobicContact CZ2-CG1 3.89Å; W18-V364 HydrophobicContact CZ2-CG2 4.18Å; V152-V364 HydrophobicContact CG1-CG2 4.2Å; L153-V364 HydrophobicContact CD2-CG2 4.17Å; I156-V364 HydrophobicContact CD1-CG1 4.4Å; I156-V364 HydrophobicContact CD1-CG2 4.13Å; L172-V364 HydrophobicContact CD2-CG1 3.87Å; V360-V364 VanDerWaalsContact O-CG2 3.27Å; V360-V364 WeakPolarHBondContact O-CG2 3.5Å; V360-V364 PolarHBondContact O-N 3.19Å; P361-V364 PolarHBondContact O-N 3Å; H362-V364 VanDerWaalsContact C-N 3.31Å; H362-V364 PolarHBondContact O-N 3.32Å; V364-A368 PolarHBondContact O-N 2.93Å
365	G	87.8	Confident	88.4	Confident	1 Å²	1	14.9 Å²	14.9	1%	0.01	9%	0.094	C	C	.	.	H	α-helix	trans	-69.4	-47.3	178.4	0	0	0	0	0	112.8	P361 H362 E363 F367 A368 I369	P361-G365 PolarHBondContact O-N 2.89Å; P361-G365 VanDerWaalsContact O-N 3.11Å; H362-G365 CarbonylContact O-C 3.56Å; H362-G365 WeakPolarHBondContact O-CA 3.3Å; H362-G365 PolarHBondContact O-N 3.15Å; E363-G365 VanDerWaalsContact C-N 3.33Å; G365-F367 VanDerWaalsContact C-N 3.26Å; G365-F367 PolarHBondContact O-N 3.4Å; G365-A368 WeakPolarHBondContact O-CA 3.29Å; G365-A368 WeakPolarHBondContact O-CB 3.43Å; G365-A368 PolarHBondContact O-N 3.04Å; G365-I369 WeakPolarHBondContact O-CG1 3.48Å; G365-I369 PolarHBondContact O-N 3.42Å
366	D	89.8	Confident	88.3	Confident	4 Å²	4	17.4 Å²	17.4	2%	0.021	11%	0.112	C	C	.	.	H	α-helix	trans	-62.1	-35.9	177.5	-71.6	-18.9	0	0	0	111.8	N322 H362 A368 I369 L370	N322-D366 VanDerWaalsContact ND2-CB 3.29Å; N322-D366 WeakPolarHBondContact ND2-CB 3.45Å; N322-D366 PolarHBondContact ND2-OD1 3.28Å; N322-D366 PolarHBondContact OD1-OD1 3.48Å; H362-D366 PolarHBondContact O-N 3.44Å; D366-A368 PolarHBondContact O-N 2.91Å; D366-I369 PolarHBondContact O-N 3.45Å; D366-L370 WeakPolarHBondContact O-CB 3.42Å; D366-L370 WeakPolarHBondContact O-CG 3.37Å; D366-L370 PolarHBondContact O-N 3.14Å
367	F	90.6	Very high	88.1	Confident	1 Å²	1	16.8 Å²	16.8	0%	0.004	11%	0.107	C	C	.	.	H	α-helix	trans	-61.8	-43.6	172.8	173.5	-96.3	0	0	0	111.6	L153 V158 E363 G365 L370 V371 K377 A380 M381	L153-F367 HydrophobicContact CD1-CB 4.34Å; L153-F367 HydrophobicContact CD1-CD2 4.34Å; L153-F367 HydrophobicContact CD2-CB 3.56Å; L153-F367 HydrophobicContact CD2-CD1 4.05Å; L153-F367 HydrophobicContact CD2-CD2 4.08Å; L153-F367 HydrophobicContact CD2-CG 3.63Å; V158-F367 HydrophobicContact CB-CE1 3.96Å; V158-F367 HydrophobicContact CB-CZ 3.96Å; V158-F367 HydrophobicContact CG1-CE1 3.66Å; V158-F367 HydrophobicContact CG1-CZ 3.58Å; V158-F367 HydrophobicContact CG2-CE1 3.66Å; V158-F367 HydrophobicContact CG2-CZ 4.17Å; E363-F367 WeakPolarHBondContact O-CB 3.4Å; E363-F367 PolarHBondContact O-N 3Å; G365-F367 VanDerWaalsContact C-N 3.26Å; G365-F367 PolarHBondContact O-N 3.4Å; F367-L370 PolarHBondContact O-N 3.43Å; F367-V371 HydrophobicContact CD2-CG2 4.47Å; F367-V371 HydrophobicContact CE1-CG2 4.14Å; F367-V371 HydrophobicContact CE2-CG2 4.08Å; F367-V371 HydrophobicContact CZ-CG2 3.9Å; F367-V371 WeakPolarHBondContact O-CB 3.41Å; F367-V371 VanDerWaalsContact O-CG2 3.3Å; F367-V371 WeakPolarHBondContact O-CG2 3.32Å; F367-V371 PolarHBondContact O-N 3.24Å; F367-K377 HydrophobicContact CE2-CB 4.36Å; F367-K377 HydrophobicContact CE2-CG 3.92Å; F367-K377 HydrophobicContact CZ-CB 4.2Å; F367-K377 HydrophobicContact CZ-CD 4.32Å; F367-K377 HydrophobicContact CZ-CG 3.84Å; F367-A380 HydrophobicContact CD2-CB 3.66Å; F367-A380 HydrophobicContact CE2-CB 3.83Å; F367-M381 HydrophobicContact CD2-CG 4.23Å; F367-M381 HydrophobicContact CE2-CG 3.97Å
368	A	89.3	Confident	88.2	Confident	0 Å²	0	20.5 Å²	20.5	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-62.6	-41.9	174.2	0	0	0	0	0	111.5	L169 L172 V364 G365 D366 V371 Q372	L169-A368 HydrophobicContact CD1-CB 3.82Å; L172-A368 HydrophobicContact CB-CB 3.8Å; V364-A368 PolarHBondContact O-N 2.93Å; G365-A368 WeakPolarHBondContact O-CA 3.29Å; G365-A368 WeakPolarHBondContact O-CB 3.43Å; G365-A368 PolarHBondContact O-N 3.04Å; D366-A368 PolarHBondContact O-N 2.91Å; A368-V371 PolarHBondContact O-N 3.38Å; A368-Q372 VanDerWaalsContact O-CB 3.24Å; A368-Q372 WeakPolarHBondContact O-CB 3.37Å; A368-Q372 PolarHBondContact O-N 3.33Å
369	I	90.2	Very high	88.3	Confident	4 Å²	4	23.7 Å²	23.7	2%	0.021	14%	0.135	C	C	.	.	H	α-helix	trans	-65.7	-40.5	178.7	-63	163.6	0	0	0	111.4	L173 A176 L180 N322 G365 D366 S373 V430 V435	L173-I369 HydrophobicContact CD1-CB 4.48Å; L173-I369 HydrophobicContact CD1-CD1 4.32Å; L173-I369 HydrophobicContact CD1-CG1 3.4Å; L173-I369 VanDerWaalsContact CD1-CG1 3.4Å; A176-I369 HydrophobicContact CB-CD1 4.1Å; L180-I369 HydrophobicContact CD1-CD1 4.13Å; N322-I369 HydrophobicContact CB-CG2 3.88Å; N322-I369 WeakPolarHBondContact OD1-CD1 3.49Å; N322-I369 VanDerWaalsContact OD1-CG2 3.25Å; N322-I369 WeakPolarHBondContact OD1-CG2 3.1Å; G365-I369 WeakPolarHBondContact O-CG1 3.48Å; G365-I369 PolarHBondContact O-N 3.42Å; D366-I369 PolarHBondContact O-N 3.45Å; I369-S373 WeakPolarHBondContact O-CB 3.1Å; I369-S373 PolarHBondContact O-N 2.96Å; I369-S373 PolarHBondContact O-OG 2.98Å; I369-V430 HydrophobicContact CD1-CG1 4.42Å; I369-V435 HydrophobicContact CD1-CG2 3.55Å; I369-V435 HydrophobicContact CG1-CG2 3.85Å
370	L	91.2	Very high	88.4	Confident	0 Å²	0	23.6 Å²	23.6	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-65.8	-45.2	176	-75.5	169.9	0	0	0	112.4	L315 L323 D366 F367 S373 G374 C375 A380 L383 Q384	L315-L370 HydrophobicContact CD1-CD2 4.49Å; L315-L370 HydrophobicContact CD2-CD2 4.33Å; L323-L370 HydrophobicContact CD1-CD2 3.98Å; L323-L370 HydrophobicContact CD2-CD1 4.06Å; L323-L370 HydrophobicContact CD2-CD2 4.12Å; L323-L370 HydrophobicContact CG-CD2 3.91Å; D366-L370 WeakPolarHBondContact O-CB 3.42Å; D366-L370 WeakPolarHBondContact O-CG 3.37Å; D366-L370 PolarHBondContact O-N 3.14Å; F367-L370 PolarHBondContact O-N 3.43Å; L370-S373 CarbonylContact O-C 3.6Å; L370-S373 PolarHBondContact O-N 3.21Å; L370-G374 PolarHBondContact O-N 3.32Å; L370-C375 HydrophobicContact CB-CB 4.36Å; L370-C375 WeakPolarHBondContact O-CB 3.22Å; L370-C375 PolarHBondContact O-N 3.2Å; L370-A380 HydrophobicContact CB-CB 3.73Å; L370-A380 HydrophobicContact CD1-CB 4.16Å; L370-L383 HydrophobicContact CD1-CB 4.33Å; L370-L383 HydrophobicContact CD2-CD1 4.34Å; L370-Q384 HydrophobicContact CD1-CG 3.64Å
371	V	89.6	Confident	88.5	Confident	24 Å²	24	22.6 Å²	22.6	15%	0.145	13%	0.129	C	C	.	.	H	α-helix	trans	-63.4	-46.3	176.7	170.9	0	0	0	0	110.7	V158 L169 F367 A368 S373 G374 C375 A380	V158-V371 HydrophobicContact CG1-CG1 4.01Å; V158-V371 HydrophobicContact CG1-CG2 3.98Å; L169-V371 HydrophobicContact CD1-CB 4.33Å; L169-V371 HydrophobicContact CD1-CG1 4.2Å; L169-V371 HydrophobicContact CD2-CG1 4.33Å; F367-V371 HydrophobicContact CD2-CG2 4.47Å; F367-V371 HydrophobicContact CE1-CG2 4.14Å; F367-V371 HydrophobicContact CE2-CG2 4.08Å; F367-V371 HydrophobicContact CZ-CG2 3.9Å; F367-V371 WeakPolarHBondContact O-CB 3.41Å; F367-V371 VanDerWaalsContact O-CG2 3.3Å; F367-V371 WeakPolarHBondContact O-CG2 3.32Å; F367-V371 PolarHBondContact O-N 3.24Å; A368-V371 PolarHBondContact O-N 3.38Å; V371-S373 PolarHBondContact O-N 2.95Å; V371-G374 PolarHBondContact O-N 2.92Å; V371-C375 WeakPolarHBondContact CA-O 3.11Å; V371-A380 HydrophobicContact CG2-CB 4.04Å
372	Q	87.6	Confident	88.9	Confident	43 Å²	43	30.1 Å²	30.1	20%	0.201	16%	0.155	C	C	.	.	H	α-helix	trans	-62.2	-29.5	173.7	-179.3	58.1	17.4	0	0	112.7	L169 L173 R316 A368 G374 E438	L169-Q372 HydrophobicContact CD2-CB 4.1Å; L173-Q372 HydrophobicContact CD2-CG 4.42Å; R316-Q372 PolarHBondContact NH1-O 3.19Å; A368-Q372 VanDerWaalsContact O-CB 3.24Å; A368-Q372 WeakPolarHBondContact O-CB 3.37Å; A368-Q372 PolarHBondContact O-N 3.33Å; Q372-G374 VanDerWaalsContact C-N 3.28Å; Q372-G374 PolarHBondContact O-N 3.07Å; Q372-E438 HydrophobicContact CG-CG 4.37Å; Q372-E438 PolarHBondContact NE2-OE1 3.01Å; Q372-E438 PolarHBondContact NE2-OE2 3.12Å
373	S	88.3	Confident	89.1	Confident	2 Å²	2	31.1 Å²	31.1	1%	0.014	16%	0.161	C	C	.	.	T	Hydrogen-bonded Turn	trans	-79.1	-6.4	176.3	-63	0	0	0	0	114	L315 R316 S318 G319 I369 L370 V371	L315-S373 VanDerWaalsContact CD1-CB 3.48Å; R316-S373 WeakPolarHBondContact CG-O 3.43Å; R316-S373 PolarHBondContact N-O 3.29Å; S318-S373 PolarHBondContact OG-OG 2.9Å; G319-S373 WeakPolarHBondContact CA-OG 3.38Å; G319-S373 PolarHBondContact N-OG 3.38Å; G319-S373 VanDerWaalsContact N-OG 3.16Å; I369-S373 WeakPolarHBondContact O-CB 3.1Å; I369-S373 PolarHBondContact O-N 2.96Å; I369-S373 PolarHBondContact O-OG 2.98Å; L370-S373 CarbonylContact O-C 3.6Å; L370-S373 PolarHBondContact O-N 3.21Å; V371-S373 PolarHBondContact O-N 2.95Å
374	G	88.2	Confident	89.2	Confident	56 Å²	56	31 Å²	31	58%	0.577	16%	0.16	S	C	*	.	T	Hydrogen-bonded Turn	trans	117.3	3.9	172.9	0	0	0	0	0	115.9	L370 V371 Q372	L370-G374 PolarHBondContact O-N 3.32Å; V371-G374 PolarHBondContact O-N 2.92Å; Q372-G374 VanDerWaalsContact C-N 3.28Å; Q372-G374 PolarHBondContact O-N 3.07Å
375	C	87.9	Confident	89.3	Confident	7 Å²	7	35.4 Å²	35.4	5%	0.047	18%	0.183	C	C	.	.			trans	-74.8	141	174.6	-70.2	0	0	0	0	112.3	L315 L370 V371 Q379 A380 L383	L315-C375 VanDerWaalsContact CD1-SG 3.57Å; L370-C375 HydrophobicContact CB-CB 4.36Å; L370-C375 WeakPolarHBondContact O-CB 3.22Å; L370-C375 PolarHBondContact O-N 3.2Å; V371-C375 WeakPolarHBondContact CA-O 3.11Å; C375-Q379 HydrophobicContact CB-CB 3.98Å; C375-A380 HydrophobicContact CB-CB 4.01Å; C375-L383 VanDerWaalsContact SG-CD1 3.53Å
376	S	88	Confident	89.5	Confident	58 Å²	58	40.2 Å²	40.2	41%	0.406	21%	0.209	S	C	.	.			trans	-65.9	156.8	155.8	62	0	0	0	0	110.7	K378 Q379 A380	S376-K378 PolarHBondContact O-N 3.37Å; S376-K378 VanDerWaalsContact O-N 3.16Å; S376-Q379 WeakPolarHBondContact O-CA 3.07Å; S376-Q379 WeakPolarHBondContact O-CB 3.49Å; S376-Q379 PolarHBondContact O-N 2.85Å; S376-Q379 VanDerWaalsContact OG-CD 3.27Å; S376-Q379 WeakPolarHBondContact OG-CG 3.45Å; S376-Q379 PolarHBondContact OG-N 3.42Å; S376-Q379 PolarHBondContact OG-OE1 3.46Å; S376-A380 PolarHBondContact O-N 2.9Å
377	K	86.6	Confident	89.6	Confident	23 Å²	23	40.2 Å²	40.2	10%	0.1	21%	0.208	C	C	.	.	H	α-helix	trans	-46	-48	175.9	173.3	168.6	-178	178.1	0	112.4	L153 F154 I156 V158 E159 F367 Q379 A380 M381	L153-K377 VanDerWaalsContact O-CE 3.27Å; L153-K377 WeakPolarHBondContact O-CE 3.41Å; L153-K377 PolarHBondContact O-NZ 2.89Å; F154-K377 PolarHBondContact O-NZ 3.49Å; I156-K377 PolarHBondContact O-NZ 3.4Å; V158-K377 HydrophobicContact CB-CD 4.49Å; V158-K377 HydrophobicContact CG1-CB 4.49Å; E159-K377 HydrophobicContact CG-CB 4.17Å; E159-K377 HydrophobicContact CG-CD 3.88Å; F367-K377 HydrophobicContact CE2-CB 4.36Å; F367-K377 HydrophobicContact CE2-CG 3.92Å; F367-K377 HydrophobicContact CZ-CB 4.2Å; F367-K377 HydrophobicContact CZ-CD 4.32Å; F367-K377 HydrophobicContact CZ-CG 3.84Å; K377-Q379 VanDerWaalsContact C-N 3.33Å; K377-Q379 PolarHBondContact O-N 3.19Å; K377-A380 PolarHBondContact O-N 2.83Å; K377-M381 HydrophobicContact CD-SD 4.42Å; K377-M381 HydrophobicContact CG-CG 4.49Å; K377-M381 HydrophobicContact CG-SD 3.79Å; K377-M381 VanDerWaalsContact O-CG 3.3Å; K377-M381 WeakPolarHBondContact O-CG 3.32Å; K377-M381 PolarHBondContact O-N 2.87Å
378	K	88	Confident	89.7	Confident	147 Å²	147	40.6 Å²	40.6	64%	0.639	21%	0.212	S	C	*	.	H	α-helix	trans	-66	-29.8	179	-65.9	178.5	-175.8	170.4	0	113.9	S376 R382	S376-K378 PolarHBondContact O-N 3.37Å; S376-K378 VanDerWaalsContact O-N 3.16Å; K378-R382 WeakPolarHBondContact O-CB 3.25Å; K378-R382 WeakPolarHBondContact O-CD 3.41Å; K378-R382 WeakPolarHBondContact O-CG 3.38Å; K378-R382 PolarHBondContact O-N 3.02Å
379	Q	90.1	Very high	89.9	Confident	67 Å²	67	44.7 Å²	44.7	31%	0.313	24%	0.237	S	C	.	.	H	α-helix	trans	-76	-44.3	174.3	-75.6	163.6	-42	0	0	111.1	C375 S376 K377 R382 L383	C375-Q379 HydrophobicContact CB-CB 3.98Å; S376-Q379 WeakPolarHBondContact O-CA 3.07Å; S376-Q379 WeakPolarHBondContact O-CB 3.49Å; S376-Q379 PolarHBondContact O-N 2.85Å; S376-Q379 VanDerWaalsContact OG-CD 3.27Å; S376-Q379 WeakPolarHBondContact OG-CG 3.45Å; S376-Q379 PolarHBondContact OG-N 3.42Å; S376-Q379 PolarHBondContact OG-OE1 3.46Å; K377-Q379 VanDerWaalsContact C-N 3.33Å; K377-Q379 PolarHBondContact O-N 3.19Å; Q379-R382 PolarHBondContact O-N 3.46Å; Q379-L383 VanDerWaalsContact O-CG 3.29Å; Q379-L383 WeakPolarHBondContact O-CG 3.47Å; Q379-L383 PolarHBondContact O-N 3.05Å
380	A	90	Very high	90	Very high	0 Å²	0	44.7 Å²	44.7	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-57	-53.6	177.2	0	0	0	0	0	111	F367 L370 V371 C375 S376 K377 R382 L383 Q384	F367-A380 HydrophobicContact CD2-CB 3.66Å; F367-A380 HydrophobicContact CE2-CB 3.83Å; L370-A380 HydrophobicContact CB-CB 3.73Å; L370-A380 HydrophobicContact CD1-CB 4.16Å; V371-A380 HydrophobicContact CG2-CB 4.04Å; C375-A380 HydrophobicContact CB-CB 4.01Å; S376-A380 PolarHBondContact O-N 2.9Å; K377-A380 PolarHBondContact O-N 2.83Å; A380-R382 PolarHBondContact O-N 3.41Å; A380-R382 VanDerWaalsContact O-N 3.16Å; A380-L383 PolarHBondContact O-N 3.15Å; A380-Q384 PolarHBondContact O-N 2.91Å; A380-Q384 PolarHBondContact O-OE1 2.89Å
381	M	89.1	Confident	90.1	Very high	12 Å²	12	44.7 Å²	44.7	6%	0.059	24%	0.238	C	C	.	.	H	α-helix	trans	-59.3	-29.7	177.5	-64.2	173	77.9	0	0	113.9	F150 L153 F154 F367 K377 L385	F150-M381 HydrophobicContact CD1-CE 4.21Å; F150-M381 HydrophobicContact CD2-CB 4.31Å; F150-M381 HydrophobicContact CD2-CE 3.92Å; F150-M381 HydrophobicContact CE1-CE 4.04Å; F150-M381 HydrophobicContact CE2-CB 3.97Å; F150-M381 HydrophobicContact CE2-CE 3.74Å; F150-M381 HydrophobicContact CG-CE 4.15Å; F150-M381 HydrophobicContact CZ-CE 3.8Å; L153-M381 HydrophobicContact CB-CE 4.07Å; L153-M381 HydrophobicContact CB-CG 4.31Å; L153-M381 HydrophobicContact CD1-CG 4.42Å; F154-M381 HydrophobicContact CB-CE 4.4Å; F367-M381 HydrophobicContact CD2-CG 4.23Å; F367-M381 HydrophobicContact CE2-CG 3.97Å; K377-M381 HydrophobicContact CD-SD 4.42Å; K377-M381 HydrophobicContact CG-CG 4.49Å; K377-M381 HydrophobicContact CG-SD 3.79Å; K377-M381 VanDerWaalsContact O-CG 3.3Å; K377-M381 WeakPolarHBondContact O-CG 3.32Å; K377-M381 PolarHBondContact O-N 2.87Å; M381-L385 WeakPolarHBondContact O-CB 3.27Å; M381-L385 PolarHBondContact O-N 2.92Å
382	R	91.3	Very high	90.4	Very high	168 Å²	168	46.7 Å²	46.7	63%	0.634	25%	0.247	S	C	*	.	H	α-helix	trans	-77.6	-30.2	175.4	-80.6	176.8	-179.8	-168.7	0.6	112.8	E309 K378 Q379 A380 L386	E309-R382 IonicContact OE1-NH1 3.69Å; K378-R382 WeakPolarHBondContact O-CB 3.25Å; K378-R382 WeakPolarHBondContact O-CD 3.41Å; K378-R382 WeakPolarHBondContact O-CG 3.38Å; K378-R382 PolarHBondContact O-N 3.02Å; Q379-R382 PolarHBondContact O-N 3.46Å; A380-R382 PolarHBondContact O-N 3.41Å; A380-R382 VanDerWaalsContact O-N 3.16Å; R382-L386 PolarHBondContact O-N 3.49Å
383	L	92	Very high	90.7	Very high	30 Å²	30	46.6 Å²	46.6	16%	0.157	25%	0.254	C	S	.	.	H	α-helix	trans	-79.9	-34.6	179.9	-70.4	165.6	0	0	0	111.2	L313 L323 L370 C375 Q379 A380 L386	L313-L383 HydrophobicContact CD2-CD1 4Å; L323-L383 HydrophobicContact CD1-CB 4.04Å; L323-L383 HydrophobicContact CD1-CD1 4.27Å; L323-L383 HydrophobicContact CD1-CD2 4.15Å; L323-L383 HydrophobicContact CD1-CG 4.38Å; L323-L383 HydrophobicContact CD2-CB 3.82Å; L370-L383 HydrophobicContact CD1-CB 4.33Å; L370-L383 HydrophobicContact CD2-CD1 4.34Å; C375-L383 VanDerWaalsContact SG-CD1 3.53Å; Q379-L383 VanDerWaalsContact O-CG 3.29Å; Q379-L383 WeakPolarHBondContact O-CG 3.47Å; Q379-L383 PolarHBondContact O-N 3.05Å; A380-L383 PolarHBondContact O-N 3.15Å; L383-L386 VanDerWaalsContact O-CB 3.25Å; L383-L386 WeakPolarHBondContact O-CB 3.42Å; L383-L386 PolarHBondContact O-N 2.84Å; L383-L386 VanDerWaalsContact O-N 3.17Å
384	Q	90.3	Very high	90.8	Very high	2 Å²	2	46.5 Å²	46.5	1%	0.009	25%	0.253	C	S	.	.	H	α-helix	trans	-65.5	-44.8	169.5	-70.5	173.4	-66.4	0	0	111.7	E363 L370 A380 L386 T387	E363-Q384 PolarHBondContact O-NE2 3.44Å; E363-Q384 VanDerWaalsContact OE2-CB 3.25Å; E363-Q384 WeakPolarHBondContact OE2-CB 3.47Å; E363-Q384 WeakPolarHBondContact OE2-CG 3.13Å; E363-Q384 PolarHBondContact OE2-NE2 3.29Å; L370-Q384 HydrophobicContact CD1-CG 3.64Å; A380-Q384 PolarHBondContact O-N 2.91Å; A380-Q384 PolarHBondContact O-OE1 2.89Å; Q384-L386 PolarHBondContact O-N 3.45Å; Q384-T387 PolarHBondContact O-N 2.85Å; Q384-T387 PolarHBondContact O-OG1 3.48Å
385	L	90	Very high	91	Very high	94 Å²	94	43.9 Å²	43.9	49%	0.492	23%	0.226	S	C	.	.	H	α-helix	trans	-60.2	-13.5	172.7	-170.5	59.7	0	0	0	113.7	M381 A388	M381-L385 WeakPolarHBondContact O-CB 3.27Å; M381-L385 PolarHBondContact O-N 2.92Å; L385-A388 WeakPolarHBondContact O-CB 3.24Å
386	L	92	Very high	91.2	Very high	103 Å²	103	44.8 Å²	44.8	54%	0.539	23%	0.234	S	C	.	.	H	α-helix	trans	-84.3	-26.8	172.2	-171.5	63.8	0	0	0	113	R382 L383 Q384 A388 V389	R382-L386 PolarHBondContact O-N 3.49Å; L383-L386 VanDerWaalsContact O-CB 3.25Å; L383-L386 WeakPolarHBondContact O-CB 3.42Å; L383-L386 PolarHBondContact O-N 2.84Å; L383-L386 VanDerWaalsContact O-N 3.17Å; Q384-L386 PolarHBondContact O-N 3.45Å; L386-A388 VanDerWaalsContact C-N 3.28Å; L386-A388 PolarHBondContact O-N 2.89Å; L386-V389 HydrophobicContact CD1-CG2 4.24Å; L386-V389 VanDerWaalsContact O-CB 3.32Å; L386-V389 WeakPolarHBondContact O-CB 3.22Å; L386-V389 VanDerWaalsContact O-CG2 3.32Å; L386-V389 WeakPolarHBondContact O-CG2 3.4Å; L386-V389 PolarHBondContact O-N 3.45Å
387	T	91.8	Very high	91.2	Very high	3 Å²	3	44.5 Å²	44.5	2%	0.018	23%	0.232	C	C	.	.	H	α-helix	trans	-74	-21.4	177.3	61.8	0	0	0	0	112.5	L323 D326 L327 Q384 V389 G390	L323-T387 HydrophobicContact CD2-CG2 3.89Å; D326-T387 HydrophobicContact CB-CG2 4.14Å; D326-T387 VanDerWaalsContact CG-CB 3.49Å; D326-T387 WeakPolarHBondContact OD1-CB 3.37Å; D326-T387 PolarHBondContact OD1-OG1 3.32Å; D326-T387 WeakPolarHBondContact OD2-CB 3.41Å; D326-T387 WeakPolarHBondContact OD2-CG2 3.42Å; D326-T387 PolarHBondContact OD2-OG1 3.21Å; L327-T387 HydrophobicContact CB-CG2 3.96Å; Q384-T387 PolarHBondContact O-N 2.85Å; Q384-T387 PolarHBondContact O-OG1 3.48Å; T387-V389 PolarHBondContact O-N 3.29Å; T387-G390 WeakPolarHBondContact O-CA 3.26Å; T387-G390 PolarHBondContact O-N 2.95Å
388	A	92.2	Very high	91.2	Very high	10 Å²	10	43.4 Å²	43.4	8%	0.083	23%	0.227	C	C	.	.	H	α-helix	trans	-49.7	-24.8	163.1	0	0	0	0	0	114.6	S146 L385 L386 G390 A391 L392	S146-A388 VanDerWaalsContact CB-CB 3.45Å; L385-A388 WeakPolarHBondContact O-CB 3.24Å; L386-A388 VanDerWaalsContact C-N 3.28Å; L386-A388 PolarHBondContact O-N 2.89Å; A388-G390 VanDerWaalsContact C-N 3.26Å; A388-G390 PolarHBondContact O-N 3.49Å; A388-A391 PolarHBondContact O-N 2.73Å; A388-L392 WeakPolarHBondContact O-CG 3.38Å; A388-L392 PolarHBondContact O-N 3.1Å
389	V	93.9	Very high	91.2	Very high	85 Å²	85	36.7 Å²	36.7	52%	0.515	20%	0.198	S	C	.	.	H	α-helix	trans	-64.6	-33.5	172.7	177.7	0	0	0	0	111.2	L386 T387 A393	L386-V389 HydrophobicContact CD1-CG2 4.24Å; L386-V389 VanDerWaalsContact O-CB 3.32Å; L386-V389 WeakPolarHBondContact O-CB 3.22Å; L386-V389 VanDerWaalsContact O-CG2 3.32Å; L386-V389 WeakPolarHBondContact O-CG2 3.4Å; L386-V389 PolarHBondContact O-N 3.45Å; T387-V389 PolarHBondContact O-N 3.29Å; V389-A393 VanDerWaalsContact O-CB 3.28Å; V389-A393 WeakPolarHBondContact O-CB 3.38Å; V389-A393 PolarHBondContact O-N 2.69Å
390	G	92.7	Very high	91.1	Very high	4 Å²	4	39.3 Å²	39.3	4%	0.041	21%	0.214	C	C	.	.	H	α-helix	trans	-58.2	-54	170.6	0	0	0	0	0	111.1	F331 T387 A388 L392 A393 G394	F331-G390 WeakPolarHBondContact CA-O 3.42Å; F331-G390 WeakPolarHBondContact CD2-O 3.36Å; T387-G390 WeakPolarHBondContact O-CA 3.26Å; T387-G390 PolarHBondContact O-N 2.95Å; A388-G390 VanDerWaalsContact C-N 3.26Å; A388-G390 PolarHBondContact O-N 3.49Å; G390-L392 PolarHBondContact O-N 3.16Å; G390-A393 WeakPolarHBondContact O-CB 3.5Å; G390-A393 PolarHBondContact O-N 3.32Å; G390-A393 VanDerWaalsContact O-N 3.13Å; G390-G394 PolarHBondContact O-N 2.95Å
391	A	93.7	Very high	90.4	Very high	0 Å²	0	40.9 Å²	40.9	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-60.7	-44.8	179.2	0	0	0	0	0	113	T142 N330 G334 A388 A393 G394 T395	T142-A391 VanDerWaalsContact CG2-C 3.47Å; T142-A391 HydrophobicContact CG2-CB 3.58Å; N330-A391 HydrophobicContact CB-CB 4.08Å; N330-A391 WeakPolarHBondContact O-CA 3.43Å; N330-A391 WeakPolarHBondContact O-CB 3.49Å; N330-A391 PolarHBondContact O-N 3.28Å; N330-A391 WeakPolarHBondContact OD1-CB 3.25Å; G334-A391 WeakPolarHBondContact CA-O 3.32Å; A388-A391 PolarHBondContact O-N 2.73Å; A391-A393 VanDerWaalsContact C-N 3.3Å; A391-A393 PolarHBondContact O-N 3.41Å; A391-G394 PolarHBondContact O-N 2.79Å; A391-T395 PolarHBondContact O-N 3.24Å; A391-T395 PolarHBondContact O-OG1 3.41Å
392	L	95.3	Very high	89	Confident	66 Å²	66	48.8 Å²	48.8	35%	0.346	26%	0.26	S	S	.	.	H	α-helix	trans	-61.7	-37.5	175.3	-69.6	170	0	0	0	112.6	L139 T142 V143 A388 G390 A396	L139-L392 HydrophobicContact CD2-CD2 4.08Å; T142-L392 HydrophobicContact CG2-CD2 3.83Å; T142-L392 HydrophobicContact CG2-CG 4.15Å; V143-L392 HydrophobicContact CG2-CD2 4.06Å; A388-L392 WeakPolarHBondContact O-CG 3.38Å; A388-L392 PolarHBondContact O-N 3.1Å; G390-L392 PolarHBondContact O-N 3.16Å; L392-A396 WeakPolarHBondContact O-CB 3.32Å; L392-A396 PolarHBondContact O-N 2.82Å
393	A	93	Very high	87.3	Confident	42 Å²	42	44 Å²	44	35%	0.347	26%	0.263	S	S	.	.	H	α-helix	trans	-68.1	-42.8	174.8	0	0	0	0	0	112	F331 V389 G390 A391 A396 C397	F331-A393 HydrophobicContact CD2-CB 4.21Å; F331-A393 HydrophobicContact CE2-CB 4.37Å; V389-A393 VanDerWaalsContact O-CB 3.28Å; V389-A393 WeakPolarHBondContact O-CB 3.38Å; V389-A393 PolarHBondContact O-N 2.69Å; G390-A393 WeakPolarHBondContact O-CB 3.5Å; G390-A393 PolarHBondContact O-N 3.32Å; G390-A393 VanDerWaalsContact O-N 3.13Å; A391-A393 VanDerWaalsContact C-N 3.3Å; A391-A393 PolarHBondContact O-N 3.41Å; A393-A396 PolarHBondContact O-N 3.05Å; A393-C397 WeakPolarHBondContact O-CB 3.38Å; A393-C397 PolarHBondContact O-N 3.2Å; A393-C397 PolarHBondContact O-SG 3.41Å; A393-C397 VanDerWaalsContact O-SG 3.33Å
394	G	90.3	Very high	85.4	Confident	0 Å²	0	42.7 Å²	42.7	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-60	-48.1	176.2	0	0	0	0	0	112.1	F331 G334 L335 G390 A391 A396 C397 A398	F331-G394 WeakPolarHBondContact O-CA 3.21Å; G334-G394 VanDerWaalsContact C-C 3.47Å; L335-G394 WeakPolarHBondContact CD2-O 3.16Å; G390-G394 PolarHBondContact O-N 2.95Å; A391-G394 PolarHBondContact O-N 2.79Å; G394-A396 PolarHBondContact O-N 3.03Å; G394-C397 WeakPolarHBondContact O-CB 3.29Å; G394-C397 PolarHBondContact O-N 3.09Å; G394-A398 PolarHBondContact O-N 3.36Å
395	T	92.5	Very high	83.5	Confident	0 Å²	0	44.3 Å²	44.3	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-59.4	-46.4	175.6	-57.7	0	0	0	0	111.4	A138 L139 T142 G334 A391 C397 A398 L399	A138-T395 HydrophobicContact CB-CG2 3.82Å; L139-T395 HydrophobicContact CD2-CG2 4Å; T142-T395 WeakPolarHBondContact OG1-CB 3.43Å; T142-T395 WeakPolarHBondContact OG1-CG2 3.21Å; T142-T395 PolarHBondContact OG1-OG1 3.41Å; G334-T395 VanDerWaalsContact C-N 3.27Å; G334-T395 WeakPolarHBondContact CA-OG1 3.35Å; G334-T395 WeakPolarHBondContact O-CA 3.48Å; G334-T395 PolarHBondContact O-N 3.04Å; G334-T395 PolarHBondContact O-OG1 3.09Å; A391-T395 PolarHBondContact O-N 3.24Å; A391-T395 PolarHBondContact O-OG1 3.41Å; T395-C397 PolarHBondContact O-N 2.99Å; T395-A398 PolarHBondContact O-N 3.39Å; T395-L399 HydrophobicContact CG2-CD1 3.89Å; T395-L399 HydrophobicContact CG2-CG 4.41Å; T395-L399 WeakPolarHBondContact O-CB 3.18Å; T395-L399 VanDerWaalsContact O-CG 3.23Å; T395-L399 WeakPolarHBondContact O-CG 3.28Å; T395-L399 PolarHBondContact O-N 2.96Å
396	A	92.3	Very high	81.6	Confident	26 Å²	26	41.8 Å²	41.8	22%	0.215	26%	0.259	C	S	.	.	H	α-helix	trans	-61.1	-42.3	176.2	0	0	0	0	0	112	L392 A393 G394 L399 L400	L392-A396 WeakPolarHBondContact O-CB 3.32Å; L392-A396 PolarHBondContact O-N 2.82Å; A393-A396 PolarHBondContact O-N 3.05Å; G394-A396 PolarHBondContact O-N 3.03Å; A396-L399 PolarHBondContact O-N 3.04Å; A396-L400 VanDerWaalsContact O-CB 3.29Å; A396-L400 WeakPolarHBondContact O-CB 3.44Å; A396-L400 WeakPolarHBondContact O-CD1 3.3Å; A396-L400 WeakPolarHBondContact O-CG 3.19Å; A396-L400 PolarHBondContact O-N 3.42Å
397	C	88.6	Confident	79.6	Confident	53 Å²	53	37 Å²	37	36%	0.358	23%	0.234	S	C	.	.	H	α-helix	trans	-59.8	-48.4	175.9	-76.7	0	0	0	0	112.3	L335 A393 G394 T395 L399 L400 T401	L335-C397 HydrophobicContact CD2-CB 3.95Å; A393-C397 WeakPolarHBondContact O-CB 3.38Å; A393-C397 PolarHBondContact O-N 3.2Å; A393-C397 PolarHBondContact O-SG 3.41Å; A393-C397 VanDerWaalsContact O-SG 3.33Å; G394-C397 WeakPolarHBondContact O-CB 3.29Å; G394-C397 PolarHBondContact O-N 3.09Å; T395-C397 PolarHBondContact O-N 2.99Å; C397-L399 PolarHBondContact O-N 2.97Å; C397-L400 PolarHBondContact O-N 3.23Å; C397-T401 VanDerWaalsContact O-CG2 3.26Å; C397-T401 WeakPolarHBondContact O-CG2 3.43Å; C397-T401 PolarHBondContact O-N 3.03Å
398	A	85.6	Confident	77.6	Confident	0 Å²	0	39.9 Å²	39.9	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-62	-41.1	177.8	0	0	0	0	0	112.4	L335 G394 T395 T401	L335-A398 HydrophobicContact CD2-CB 4.21Å; L335-A398 WeakPolarHBondContact O-CB 3.45Å; G394-A398 PolarHBondContact O-N 3.36Å; T395-A398 PolarHBondContact O-N 3.39Å; A398-T401 PolarHBondContact O-OG1 2.72Å
399	L	88.7	Confident	75.6	Confident	6 Å²	6	42.8 Å²	42.8	3%	0.031	27%	0.266	C	S	.	.	H	α-helix	trans	-71.6	-37.5	179.4	-67.2	173.7	0	0	0	113.7	L134 W135 A138 R342 T395 A396 C397 T401	L134-L399 HydrophobicContact CD1-CD2 4.21Å; L134-L399 HydrophobicContact CD2-CD2 4.08Å; L134-L399 HydrophobicContact CG-CD2 3.86Å; W135-L399 HydrophobicContact CB-CD1 4.46Å; W135-L399 HydrophobicContact CD2-CB 4.24Å; W135-L399 HydrophobicContact CD2-CD1 3.68Å; W135-L399 HydrophobicContact CE3-CD1 3.89Å; W135-L399 HydrophobicContact CG-CD1 3.93Å; W135-L399 HydrophobicContact CH2-CB 4.19Å; W135-L399 HydrophobicContact CZ2-CB 3.64Å; W135-L399 HydrophobicContact CZ2-CD1 4.48Å; W135-L399 HydrophobicContact CZ3-CD1 4.37Å; A138-L399 HydrophobicContact CB-CD1 3.92Å; A138-L399 HydrophobicContact CB-CD2 4.17Å; A138-L399 HydrophobicContact CB-CG 4.43Å; R342-L399 PolarHBondContact NH1-O 3.01Å; T395-L399 HydrophobicContact CG2-CD1 3.89Å; T395-L399 HydrophobicContact CG2-CG 4.41Å; T395-L399 WeakPolarHBondContact O-CB 3.18Å; T395-L399 VanDerWaalsContact O-CG 3.23Å; T395-L399 WeakPolarHBondContact O-CG 3.28Å; T395-L399 PolarHBondContact O-N 2.96Å; A396-L399 PolarHBondContact O-N 3.04Å; C397-L399 PolarHBondContact O-N 2.97Å; L399-T401 VanDerWaalsContact C-N 3.31Å; L399-T401 PolarHBondContact O-N 3.36Å
400	L	87.3	Confident	73.4	Confident	122 Å²	122	39.6 Å²	39.6	64%	0.639	25%	0.246	S	C	*	.	H	α-helix	trans	-69.2	-26.8	179	-75.8	169.1	0	0	0	113.1	W135 A396 C397 E402	W135-L400 HydrophobicContact CH2-CD2 3.87Å; W135-L400 HydrophobicContact CH2-CG 3.84Å; W135-L400 HydrophobicContact CZ2-CD2 3.89Å; W135-L400 HydrophobicContact CZ2-CG 4.03Å; A396-L400 VanDerWaalsContact O-CB 3.29Å; A396-L400 WeakPolarHBondContact O-CB 3.44Å; A396-L400 WeakPolarHBondContact O-CD1 3.3Å; A396-L400 WeakPolarHBondContact O-CG 3.19Å; A396-L400 PolarHBondContact O-N 3.42Å; C397-L400 PolarHBondContact O-N 3.23Å; L400-E402 PolarHBondContact O-N 3.47Å
401	T	75.5	Confident	71.2	Confident	33 Å²	33	41.4 Å²	41.4	20%	0.202	26%	0.261	C	S	.	.	S	Bend	trans	-73.9	122.4	180	60.9	0	0	0	0	111.2	R342 C397 A398 L399 G404 A405 V406	R342-T401 VanDerWaalsContact CZ-O 3.23Å; R342-T401 PolarHBondContact NH1-O 3.31Å; R342-T401 PolarHBondContact NH2-O 2.9Å; C397-T401 VanDerWaalsContact O-CG2 3.26Å; C397-T401 WeakPolarHBondContact O-CG2 3.43Å; C397-T401 PolarHBondContact O-N 3.03Å; A398-T401 PolarHBondContact O-OG1 2.72Å; L399-T401 VanDerWaalsContact C-N 3.31Å; L399-T401 PolarHBondContact O-N 3.36Å; T401-G404 WeakPolarHBondContact O-CA 3.23Å; T401-G404 PolarHBondContact O-N 2.84Å; T401-G404 VanDerWaalsContact OG1-C 3.26Å; T401-G404 WeakPolarHBondContact OG1-CA 3.35Å; T401-A405 PolarHBondContact OG1-N 2.78Å; T401-V406 HydrophobicContact CG2-CB 3.78Å; T401-V406 HydrophobicContact CG2-CG2 3.42Å; T401-V406 VanDerWaalsContact CG2-CG2 3.42Å; T401-V406 PolarHBondContact OG1-N 2.86Å
402	E	59.4	Low	68.7	Low	177 Å²	177	42.3 Å²	42.3	83%	0.827	27%	0.27	S	S	*	.	G	3₁₀ helix	trans	-61.5	142.3	173.4	-67.6	-173.5	171.4	0	0	110.2	L400 G404 A405	L400-E402 PolarHBondContact O-N 3.47Å; E402-G404 PolarHBondContact O-N 3.34Å; E402-A405 PolarHBondContact O-N 3.47Å
403	G	57.1	Low	66	Low	68 Å²	68	41.6 Å²	41.6	70%	0.701	28%	0.279	S	S	*	.	G	3₁₀ helix	trans	65.9	-3.7	-167.3	0	0	0	0	0	115.1
404	G	52.4	Low	63.5	Low	2 Å²	2	43.4 Å²	43.4	2%	0.021	29%	0.294	C	S	.	.	G	3₁₀ helix	trans	69.1	20.4	-169.4	0	0	0	0	0	112.7	R342 T401 E402 V406 G407 S408	R342-G404 VanDerWaalsContact CD-CA 3.47Å; T401-G404 WeakPolarHBondContact O-CA 3.23Å; T401-G404 PolarHBondContact O-N 2.84Å; T401-G404 VanDerWaalsContact OG1-C 3.26Å; T401-G404 WeakPolarHBondContact OG1-CA 3.35Å; E402-G404 PolarHBondContact O-N 3.34Å; G404-V406 VanDerWaalsContact C-N 3.31Å; G404-V406 PolarHBondContact O-N 3.13Å; G404-V406 VanDerWaalsContact O-N 3.13Å; G404-G407 CarbonylContact O-C 3.57Å; G404-G407 WeakPolarHBondContact O-CA 3.37Å; G404-G407 PolarHBondContact O-N 3.44Å; G404-S408 WeakPolarHBondContact O-CB 3.43Å; G404-S408 PolarHBondContact O-N 3.45Å
405	A	49.5	Very low	61.6	Low	36 Å²	36	44.3 Å²	44.3	30%	0.298	30%	0.303	S	S	.	.	H	α-helix	trans	-47.7	-47.6	-166.2	0	0	0	0	0	113.3	T401 E402 G407 S408 E409	T401-A405 PolarHBondContact OG1-N 2.78Å; E402-A405 PolarHBondContact O-N 3.47Å; A405-G407 PolarHBondContact O-N 3.01Å; A405-S408 PolarHBondContact O-N 3.01Å; A405-E409 WeakPolarHBondContact O-CA 3.39Å; A405-E409 WeakPolarHBondContact O-CB 3.44Å; A405-E409 WeakPolarHBondContact O-CG 3.48Å; A405-E409 PolarHBondContact O-N 3.38Å
406	V	50.7	Low	59.8	Low	41 Å²	41	46 Å²	46	25%	0.248	31%	0.314	C	S	.	.	H	α-helix	trans	-62.4	-43.1	179.1	172.5	0	0	0	0	111.9	L335 T401 G404 I410 P416	L335-V406 HydrophobicContact CD2-CG1 3.84Å; T401-V406 HydrophobicContact CG2-CB 3.78Å; T401-V406 HydrophobicContact CG2-CG2 3.42Å; T401-V406 VanDerWaalsContact CG2-CG2 3.42Å; T401-V406 PolarHBondContact OG1-N 2.86Å; G404-V406 VanDerWaalsContact C-N 3.31Å; G404-V406 PolarHBondContact O-N 3.13Å; G404-V406 VanDerWaalsContact O-N 3.13Å; V406-I410 HydrophobicContact CG1-CD1 3.82Å; V406-I410 VanDerWaalsContact O-CB 3.28Å; V406-I410 WeakPolarHBondContact O-CB 3.33Å; V406-I410 VanDerWaalsContact O-CD1 3.3Å; V406-I410 WeakPolarHBondContact O-CD1 3.4Å; V406-I410 WeakPolarHBondContact O-CG1 3.31Å; V406-I410 PolarHBondContact O-N 2.68Å; V406-P416 HydrophobicContact CG1-CG 3.84Å
407	G	50.1	Low	58.5	Low	2 Å²	2	46.1 Å²	46.1	2%	0.021	32%	0.318	C	S	.	.	H	α-helix	trans	-72.3	-39.9	178.4	0	0	0	0	0	113.8	G404 A405 A411	G404-G407 CarbonylContact O-C 3.57Å; G404-G407 WeakPolarHBondContact O-CA 3.37Å; G404-G407 PolarHBondContact O-N 3.44Å; A405-G407 PolarHBondContact O-N 3.01Å; G407-A411 VanDerWaalsContact O-CB 3.3Å; G407-A411 WeakPolarHBondContact O-CB 3.45Å; G407-A411 PolarHBondContact O-N 3.27Å
408	S	49.2	Very low	58.1	Low	65 Å²	65	48.8 Å²	48.8	46%	0.455	32%	0.32	S	S	.	.	H	α-helix	trans	-78.5	-19.5	179.6	-172	0	0	0	0	113.5	G404 A405 A411 G412	G404-S408 WeakPolarHBondContact O-CB 3.43Å; G404-S408 PolarHBondContact O-N 3.45Å; A405-S408 PolarHBondContact O-N 3.01Å; S408-A411 CarbonylContact O-C 3.56Å; S408-G412 WeakPolarHBondContact O-CA 3.46Å; S408-G412 PolarHBondContact O-N 2.94Å; S408-G412 VanDerWaalsContact O-N 3.09Å
409	E	49.2	Very low	57.8	Low	71 Å²	71	49.3 Å²	49.3	33%	0.332	32%	0.324	S	S	.	.	H	α-helix	trans	-92.1	-30.2	173.4	-67.1	178.6	-180	0	0	111.1	A405 A411 G412 G413 A414 G415	A405-E409 WeakPolarHBondContact O-CA 3.39Å; A405-E409 WeakPolarHBondContact O-CB 3.44Å; A405-E409 WeakPolarHBondContact O-CG 3.48Å; A405-E409 PolarHBondContact O-N 3.38Å; E409-A411 VanDerWaalsContact C-N 3.34Å; E409-G412 CarbonylContact O-C 3Å; E409-G412 PolarHBondContact O-N 2.94Å; E409-G412 VanDerWaalsContact O-N 3.14Å; E409-G413 PolarHBondContact O-N 2.97Å; E409-A414 HydrophobicContact CB-CB 4.42Å; E409-A414 HydrophobicContact CG-CB 4.06Å; E409-A414 PolarHBondContact O-N 3.2Å; E409-G415 CarbonylContact C-O 3.59Å; E409-G415 WeakPolarHBondContact CB-O 3.36Å; E409-G415 WeakPolarHBondContact OE2-CA 3.29Å
410	I	49	Very low	57.6	Low	17 Å²	17	49.6 Å²	49.6	9%	0.087	33%	0.325	C	S	.	.	H	α-helix	trans	-63.3	-43	164.6	-72.5	168.6	0	0	0	109.9	L335 V406 G412 G415 P416 L420	L335-I410 HydrophobicContact CB-CD1 4.3Å; L335-I410 HydrophobicContact CD1-CD1 3.56Å; L335-I410 HydrophobicContact CD2-CD1 4.1Å; L335-I410 HydrophobicContact CG-CD1 4.2Å; V406-I410 HydrophobicContact CG1-CD1 3.82Å; V406-I410 VanDerWaalsContact O-CB 3.28Å; V406-I410 WeakPolarHBondContact O-CB 3.33Å; V406-I410 VanDerWaalsContact O-CD1 3.3Å; V406-I410 WeakPolarHBondContact O-CD1 3.4Å; V406-I410 WeakPolarHBondContact O-CG1 3.31Å; V406-I410 PolarHBondContact O-N 2.68Å; I410-G412 VanDerWaalsContact C-N 3.25Å; I410-G412 PolarHBondContact O-N 3.02Å; I410-G415 PolarHBondContact N-O 2.9Å; I410-P416 HydrophobicContact CD1-CG 3.98Å; I410-P416 HydrophobicContact CG1-CG 3.91Å; I410-L420 HydrophobicContact CG2-CD1 3.99Å; I410-L420 HydrophobicContact CG2-CG 4.26Å
411	A	46.6	Very low	57.7	Low	43 Å²	43	43.8 Å²	43.8	36%	0.355	30%	0.295	S	S	.	.	T	Hydrogen-bonded Turn	trans	-82.8	9.6	171.3	0	0	0	0	0	114.1	H196 G407 S408 E409	H196-A411 PolarHBondContact CD2-O 3.01Å; G407-A411 VanDerWaalsContact O-CB 3.3Å; G407-A411 WeakPolarHBondContact O-CB 3.45Å; G407-A411 PolarHBondContact O-N 3.27Å; S408-A411 CarbonylContact O-C 3.56Å; E409-A411 VanDerWaalsContact C-N 3.34Å
412	G	40.8	Very low	58.4	Low	18 Å²	18	44.5 Å²	44.5	19%	0.186	30%	0.295	C	S	.	.	T	Hydrogen-bonded Turn	trans	-149.6	16.9	-169.4	0	0	0	0	0	115.7	S408 E409 I410 A414	S408-G412 WeakPolarHBondContact O-CA 3.46Å; S408-G412 PolarHBondContact O-N 2.94Å; S408-G412 VanDerWaalsContact O-N 3.09Å; E409-G412 CarbonylContact O-C 3Å; E409-G412 PolarHBondContact O-N 2.94Å; E409-G412 VanDerWaalsContact O-N 3.14Å; I410-G412 VanDerWaalsContact C-N 3.25Å; I410-G412 PolarHBondContact O-N 3.02Å; G412-A414 PolarHBondContact O-N 2.93Å
413	G	39.1	Very low	59.7	Low	52 Å²	52	36.2 Å²	36.2	54%	0.536	26%	0.257	S	S	.	.	S	Bend	trans	66.5	-5.9	170.1	0	0	0	0	0	118.7	E409	E409-G413 PolarHBondContact O-N 2.97Å
414	A	39.1	Very low	61.4	Low	79 Å²	79	33 Å²	33	65%	0.653	22%	0.223	S	C	*	.	S	Bend	trans	-95.3	-4.3	-169.3	0	0	0	0	0	115.7	E409 G412	E409-A414 HydrophobicContact CB-CB 4.42Å; E409-A414 HydrophobicContact CG-CB 4.06Å; E409-A414 PolarHBondContact O-N 3.2Å; G412-A414 PolarHBondContact O-N 2.93Å
415	G	50.3	Low	63.4	Low	20 Å²	20	32.9 Å²	32.9	21%	0.206	22%	0.222	C	C	.	.	S	Bend	trans	168	172.2	-171.9	0	0	0	0	0	111.2	E409 I410 G417	E409-G415 CarbonylContact C-O 3.59Å; E409-G415 WeakPolarHBondContact CB-O 3.36Å; E409-G415 WeakPolarHBondContact OE2-CA 3.29Å; I410-G415 PolarHBondContact N-O 2.9Å; G415-G417 PolarHBondContact O-N 3.42Å
416	P	54.5	Low	65.4	Low	36 Å²	36	31.2 Å²	31.2	23%	0.234	21%	0.208	C	C	.	.	S	Bend		-44.6	60.9	-101.1	36.9	-37.9	0	0	0	116.2	V406 I410 W418 V419	V406-P416 HydrophobicContact CG1-CG 3.84Å; I410-P416 HydrophobicContact CD1-CG 3.98Å; I410-P416 HydrophobicContact CG1-CG 3.91Å; P416-W418 PolarHBondContact O-N 3.45Å; P416-V419 HydrophobicContact CB-CG2 4.47Å; P416-V419 WeakPolarHBondContact O-CG2 3.39Å; P416-V419 PolarHBondContact O-N 3.47Å
417	G	66.1	Low	67.4	Low	28 Å²	28	29.3 Å²	29.3	29%	0.289	20%	0.197	S	C	.	.	T	Hydrogen-bonded Turn	trans	-65.9	13.6	174.7	0	0	0	0	0	115.1	G415 P421	G415-G417 PolarHBondContact O-N 3.42Å; G417-P421 WeakPolarHBondContact O-CD 3.38Å; G417-P421 VanDerWaalsContact O-CG 3.31Å; G417-P421 WeakPolarHBondContact O-CG 3.48Å
418	W	79.3	Confident	69.6	Low	108 Å²	108	30 Å²	30	41%	0.409	20%	0.2	S	C	.	.	T	Hydrogen-bonded Turn	trans	-81.9	-23	169	64.2	-98.8	0	0	0	112.8	W222 P416 P421 F422	W222-W418 HydrophobicContact CB-CB 4.48Å; W222-W418 HydrophobicContact CD2-CB 3.38Å; W222-W418 HydrophobicContact CD2-CG 4.4Å; W222-W418 HydrophobicContact CE3-CB 3.88Å; W222-W418 HydrophobicContact CG-CB 3.63Å; W222-W418 HydrophobicContact CH2-CB 4.22Å; W222-W418 HydrophobicContact CH2-CG 4.34Å; W222-W418 HydrophobicContact CZ2-CB 3.76Å; W222-W418 HydrophobicContact CZ2-CG 4.19Å; W222-W418 HydrophobicContact CZ3-CB 4.27Å; W222-W418 HydrophobicContact CZ3-CE3 4.44Å; P416-W418 PolarHBondContact O-N 3.45Å; W418-P421 WeakPolarHBondContact O-CD 3.21Å; W418-P421 WeakPolarHBondContact O-CG 3.16Å; W418-F422 HydrophobicContact CE3-CB 4.11Å; W418-F422 HydrophobicContact CE3-CG 4.42Å; W418-F422 HydrophobicContact CZ3-CB 4.49Å; W418-F422 HydrophobicContact CZ3-CG 4.4Å; W418-F422 WeakPolarHBondContact O-CB 3.33Å; W418-F422 PolarHBondContact O-N 2.94Å
419	V	79.3	Confident	71.7	Confident	11 Å²	11	27.6 Å²	27.6	7%	0.067	18%	0.181	C	C	.	.	H	α-helix	trans	-66.8	-50.3	-173.7	-170.8	0	0	0	0	110.9	F331 T332 P416 F422 T423	F331-V419 HydrophobicContact CD1-CG1 4.27Å; F331-V419 HydrophobicContact CE1-CG1 4.37Å; T332-V419 HydrophobicContact CG2-CB 4.12Å; T332-V419 HydrophobicContact CG2-CG1 3.39Å; P416-V419 HydrophobicContact CB-CG2 4.47Å; P416-V419 WeakPolarHBondContact O-CG2 3.39Å; P416-V419 PolarHBondContact O-N 3.47Å; V419-F422 PolarHBondContact O-N 2.83Å; V419-T423 PolarHBondContact O-N 2.94Å; V419-T423 PolarHBondContact O-OG1 2.9Å
420	L	84.5	Confident	73.8	Confident	13 Å²	13	24.3 Å²	24.3	7%	0.068	17%	0.166	C	C	.	.	H	α-helix	trans	-53.7	-54.5	177.3	-64.7	170.4	0	0	0	113.1	L188 H191 A192 T332 I410 F422 T423 A424	L188-L420 HydrophobicContact CD2-CD2 3.69Å; H191-L420 HydrophobicContact CB-CD1 4.48Å; A192-L420 HydrophobicContact CB-CB 4.27Å; T332-L420 HydrophobicContact CG2-CD2 3.91Å; I410-L420 HydrophobicContact CG2-CD1 3.99Å; I410-L420 HydrophobicContact CG2-CG 4.26Å; L420-F422 VanDerWaalsContact C-N 3.34Å; L420-F422 PolarHBondContact O-N 2.96Å; L420-T423 PolarHBondContact O-N 3.42Å; L420-A424 PolarHBondContact O-N 2.99Å
421	P	90	Very high	75.9	Confident	0 Å²	0	23.5 Å²	23.5	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-66.8	-33.2	177.6	22.6	-30.2	0	0	0	113	A192 V219 W222 V223 G417 W418 A424 G425	A192-P421 HydrophobicContact CB-CB 4.44Å; A192-P421 HydrophobicContact CB-CG 4.14Å; V219-P421 HydrophobicContact CG1-CB 4.03Å; W222-P421 HydrophobicContact CB-CB 3.83Å; W222-P421 HydrophobicContact CB-CG 3.6Å; W222-P421 HydrophobicContact CG-CG 4.39Å; V223-P421 VanDerWaalsContact CA-O 3.24Å; V223-P421 WeakPolarHBondContact CA-O 3.14Å; V223-P421 HydrophobicContact CG2-CB 3.64Å; V223-P421 WeakPolarHBondContact CG2-O 3.34Å; G417-P421 WeakPolarHBondContact O-CD 3.38Å; G417-P421 VanDerWaalsContact O-CG 3.31Å; G417-P421 WeakPolarHBondContact O-CG 3.48Å; W418-P421 WeakPolarHBondContact O-CD 3.21Å; W418-P421 WeakPolarHBondContact O-CG 3.16Å; P421-A424 WeakPolarHBondContact O-CB 3.47Å; P421-A424 PolarHBondContact O-N 2.92Å; P421-G425 PolarHBondContact O-N 3.08Å
422	F	89.9	Confident	78.2	Confident	48 Å²	48	24.3 Å²	24.3	21%	0.211	16%	0.162	C	C	.	.	H	α-helix	trans	-62.9	-45.3	174.1	-179.3	-87.2	0	0	0	111.8	W222 G226 A229 W418 V419 L420 G425 G426	W222-F422 WeakPolarHBondContact O-CA 3.04Å; G226-F422 WeakPolarHBondContact CA-O 3.45Å; A229-F422 HydrophobicContact CB-CE2 3.79Å; A229-F422 HydrophobicContact CB-CZ 3.7Å; W418-F422 HydrophobicContact CE3-CB 4.11Å; W418-F422 HydrophobicContact CE3-CG 4.42Å; W418-F422 HydrophobicContact CZ3-CB 4.49Å; W418-F422 HydrophobicContact CZ3-CG 4.4Å; W418-F422 WeakPolarHBondContact O-CB 3.33Å; W418-F422 PolarHBondContact O-N 2.94Å; V419-F422 PolarHBondContact O-N 2.83Å; L420-F422 VanDerWaalsContact C-N 3.34Å; L420-F422 PolarHBondContact O-N 2.96Å; F422-G425 PolarHBondContact O-N 3.32Å; F422-G426 PolarHBondContact O-N 3.29Å
423	T	87.6	Confident	80.7	Confident	3 Å²	3	26.1 Å²	26.1	2%	0.018	17%	0.17	C	C	.	.	H	α-helix	trans	-61.2	-44.7	173.8	-61.9	0	0	0	0	111	L188 H329 V419 L420 G425 G426 F427	L188-T423 HydrophobicContact CD1-CG2 3.88Å; H329-T423 HydrophobicContact CB-CG2 3.91Å; V419-T423 PolarHBondContact O-N 2.94Å; V419-T423 PolarHBondContact O-OG1 2.9Å; L420-T423 PolarHBondContact O-N 3.42Å; T423-G425 VanDerWaalsContact C-N 3.26Å; T423-G425 PolarHBondContact O-N 3.03Å; T423-G426 CarbonylContact O-C 3.55Å; T423-G426 WeakPolarHBondContact O-CA 3.36Å; T423-G426 PolarHBondContact O-N 2.86Å; T423-F427 HydrophobicContact CG2-CD1 4.37Å; T423-F427 HydrophobicContact CG2-CE1 4.38Å; T423-F427 PolarHBondContact O-N 3.17Å
424	A	92.6	Very high	83	Confident	0 Å²	0	24.7 Å²	24.7	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-56.8	-40	174.6	0	0	0	0	0	112.2	A184 L188 I189 L420 P421 F427 I428	A184-A424 HydrophobicContact CB-CB 4Å; L188-A424 HydrophobicContact CB-CB 3.78Å; L188-A424 HydrophobicContact CD1-CB 3.91Å; I189-A424 HydrophobicContact CD1-CB 4.19Å; I189-A424 HydrophobicContact CG1-CB 3.8Å; L420-A424 PolarHBondContact O-N 2.99Å; P421-A424 WeakPolarHBondContact O-CB 3.47Å; P421-A424 PolarHBondContact O-N 2.92Å; A424-F427 PolarHBondContact O-N 3.35Å; A424-I428 WeakPolarHBondContact O-CB 3.49Å; A424-I428 WeakPolarHBondContact O-CD1 3.37Å; A424-I428 VanDerWaalsContact O-CG1 3.24Å; A424-I428 WeakPolarHBondContact O-CG1 3.49Å; A424-I428 PolarHBondContact O-N 2.91Å
425	G	94	Very high	85.4	Confident	0 Å²	0	21 Å²	21	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-62.2	-39.5	172.6	0	0	0	0	0	113.5	V223 I227 P421 F422 T423 Y429	V223-G425 WeakPolarHBondContact O-CA 3.27Å; I227-G425 VanDerWaalsContact CG1-O 3.22Å; I227-G425 WeakPolarHBondContact CG1-O 3.3Å; P421-G425 PolarHBondContact O-N 3.08Å; F422-G425 PolarHBondContact O-N 3.32Å; T423-G425 VanDerWaalsContact C-N 3.26Å; T423-G425 PolarHBondContact O-N 3.03Å; G425-Y429 WeakPolarHBondContact O-CB 3.43Å; G425-Y429 PolarHBondContact O-N 3.34Å
426	G	90.8	Very high	87.4	Confident	0 Å²	0	22.3 Å²	22.3	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-63.9	-45.6	172.3	0	0	0	0	0	112.8	F422 T423 Y429 V430	F422-G426 PolarHBondContact O-N 3.29Å; T423-G426 CarbonylContact O-C 3.55Å; T423-G426 WeakPolarHBondContact O-CA 3.36Å; T423-G426 PolarHBondContact O-N 2.86Å; G426-Y429 WeakPolarHBondContact O-CB 3.32Å; G426-Y429 PolarHBondContact O-N 3.09Å; G426-Y429 VanDerWaalsContact O-N 3.13Å; G426-V430 WeakPolarHBondContact O-CG2 3.41Å; G426-V430 PolarHBondContact O-N 2.97Å
427	F	93.1	Very high	89.2	Confident	1 Å²	1	23.4 Å²	23.4	0%	0.004	13%	0.13	C	C	.	.	H	α-helix	trans	-62.2	-46	177.4	-87.1	21.8	0	0	0	112.2	L180 D183 A184 L188 A325 H329 H362 T423 A424 Y429 V430 A431	L180-F427 HydrophobicContact CB-CD2 4.5Å; L180-F427 HydrophobicContact CD2-CD1 3.98Å; L180-F427 HydrophobicContact CD2-CD2 3.67Å; L180-F427 HydrophobicContact CD2-CE1 3.91Å; L180-F427 HydrophobicContact CD2-CE2 3.62Å; L180-F427 HydrophobicContact CD2-CG 3.82Å; L180-F427 HydrophobicContact CD2-CZ 3.72Å; D183-F427 HydrophobicContact CB-CD2 4.23Å; D183-F427 HydrophobicContact CB-CE2 4.33Å; D183-F427 WeakPolarHBondContact OD2-CD2 3.48Å; D183-F427 WeakPolarHBondContact OD2-CE2 3.28Å; A184-F427 HydrophobicContact CB-CB 4.08Å; L188-F427 HydrophobicContact CD1-CD2 4.36Å; A325-F427 HydrophobicContact CB-CD1 3.83Å; A325-F427 HydrophobicContact CB-CE1 3.85Å; H329-F427 HydrophobicContact CB-CE1 3.74Å; H329-F427 HydrophobicContact CB-CE2 4.22Å; H329-F427 HydrophobicContact CB-CZ 3.36Å; H329-F427 AromaticContact CE1-CE2 3.71Å; H329-F427 AromaticContact CG-CE2 3.78Å; H329-F427 AromaticContact CG-CZ 3.35Å; H329-F427 AromaticContact ND1-CE2 3.23Å; H329-F427 WeakPolarHBondContact ND1-CE2 3.44Å; H329-F427 AromaticContact ND1-CZ 3.32Å; H329-F427 VanDerWaalsContact ND1-CZ 3.32Å; H329-F427 WeakPolarHBondContact ND1-CZ 3.29Å; H362-F427 AromaticContact CE1-CE2 3.79Å; T423-F427 HydrophobicContact CG2-CD1 4.37Å; T423-F427 HydrophobicContact CG2-CE1 4.38Å; T423-F427 PolarHBondContact O-N 3.17Å; A424-F427 PolarHBondContact O-N 3.35Å; F427-Y429 VanDerWaalsContact C-N 3.27Å; F427-Y429 PolarHBondContact O-N 3.01Å; F427-V430 PolarHBondContact O-N 2.98Å; F427-A431 WeakPolarHBondContact O-CB 3.26Å; F427-A431 PolarHBondContact O-N 3.19Å
428	I	96.1	Very high	90.2	Very high	18 Å²	18	23.4 Å²	23.4	9%	0.092	12%	0.122	C	C	.	.	H	α-helix	trans	-57.2	-42.6	172.2	-69.8	163.4	0	0	0	110.3	L181 A184 F185 I189 V223 I227 A424 T432	L181-I428 HydrophobicContact CD2-CG1 4.38Å; A184-I428 HydrophobicContact CB-CD1 4.15Å; A184-I428 HydrophobicContact CB-CG1 3.76Å; F185-I428 HydrophobicContact CE1-CD1 4.21Å; F185-I428 HydrophobicContact CE2-CD1 3.86Å; F185-I428 HydrophobicContact CE2-CG1 3.86Å; F185-I428 HydrophobicContact CZ-CD1 3.66Å; F185-I428 HydrophobicContact CZ-CG1 4.16Å; I189-I428 HydrophobicContact CD1-CD1 4.22Å; V223-I428 HydrophobicContact CG1-CD1 4.04Å; I227-I428 HydrophobicContact CD1-CG2 4.18Å; A424-I428 WeakPolarHBondContact O-CB 3.49Å; A424-I428 WeakPolarHBondContact O-CD1 3.37Å; A424-I428 VanDerWaalsContact O-CG1 3.24Å; A424-I428 WeakPolarHBondContact O-CG1 3.49Å; A424-I428 PolarHBondContact O-N 2.91Å; I428-T432 HydrophobicContact CG2-CG2 4.31Å; I428-T432 VanDerWaalsContact O-CB 3.32Å; I428-T432 WeakPolarHBondContact O-CB 3.4Å; I428-T432 WeakPolarHBondContact O-CG2 3.41Å; I428-T432 PolarHBondContact O-N 3.47Å; I428-T432 PolarHBondContact O-OG1 3.43Å
429	Y	94.5	Very high	90.6	Very high	14 Å²	14	19.3 Å²	19.3	6%	0.055	11%	0.108	C	C	.	.	H	α-helix	trans	-64.8	-48.9	178.3	-168.5	-86	0	0	0	112.7	I227 F230 L231 E234 L321 G425 G426 F427 T432 V433	I227-Y429 HydrophobicContact CG2-CD2 4.16Å; F230-Y429 HydrophobicContact CB-CD1 3.64Å; F230-Y429 HydrophobicContact CB-CD2 4.23Å; F230-Y429 HydrophobicContact CB-CE1 4.26Å; F230-Y429 HydrophobicContact CB-CG 3.63Å; F230-Y429 HydrophobicContact CD1-CD1 4.42Å; L231-Y429 WeakPolarHBondContact CA-OH 3.41Å; L231-Y429 HydrophobicContact CB-CD2 4.43Å; L231-Y429 HydrophobicContact CB-CE2 3.62Å; L231-Y429 HydrophobicContact CD1-CE2 4.35Å; L231-Y429 HydrophobicContact CG-CE2 4.19Å; E234-Y429 HydrophobicContact CB-CE1 4.38Å; E234-Y429 WeakPolarHBondContact OE2-CE1 3.27Å; E234-Y429 PolarHBondContact OE2-OH 3.42Å; L321-Y429 HydrophobicContact CD1-CE1 4.21Å; G425-Y429 WeakPolarHBondContact O-CB 3.43Å; G425-Y429 PolarHBondContact O-N 3.34Å; G426-Y429 WeakPolarHBondContact O-CB 3.32Å; G426-Y429 PolarHBondContact O-N 3.09Å; G426-Y429 VanDerWaalsContact O-N 3.13Å; F427-Y429 VanDerWaalsContact C-N 3.27Å; F427-Y429 PolarHBondContact O-N 3.01Å; Y429-T432 PolarHBondContact O-N 2.91Å; Y429-V433 HydrophobicContact CD1-CB 4.23Å; Y429-V433 HydrophobicContact CD2-CG2 3.95Å; Y429-V433 HydrophobicContact CE1-CB 3.95Å; Y429-V433 HydrophobicContact CE1-CG1 4.05Å; Y429-V433 HydrophobicContact CE1-CG2 4.38Å; Y429-V433 HydrophobicContact CE2-CB 4.24Å; Y429-V433 HydrophobicContact CE2-CG1 4.37Å; Y429-V433 HydrophobicContact CE2-CG2 3.79Å; Y429-V433 HydrophobicContact CG-CG2 4.31Å; Y429-V433 WeakPolarHBondContact O-CA 3.32Å; Y429-V433 VanDerWaalsContact O-CB 3.29Å; Y429-V433 WeakPolarHBondContact O-CB 3.44Å; Y429-V433 PolarHBondContact O-N 3.14Å
430	V	92.4	Very high	91.2	Very high	1 Å²	1	25.7 Å²	25.7	1%	0.006	14%	0.141	C	C	.	.	I	π-helix	trans	-59.8	-50.7	178.6	171.7	0	0	0	0	110.1	L180 F230 L321 N322 A325 I369 G426 F427 S434 V435	L180-V430 HydrophobicContact CD1-CG1 3.96Å; F230-V430 HydrophobicContact CD1-CG2 4.16Å; F230-V430 HydrophobicContact CE1-CG2 4.12Å; L321-V430 HydrophobicContact CB-CG2 4.31Å; N322-V430 WeakPolarHBondContact OD1-CG1 3.29Å; A325-V430 HydrophobicContact CB-CG2 3.86Å; I369-V430 HydrophobicContact CD1-CG1 4.42Å; G426-V430 WeakPolarHBondContact O-CG2 3.41Å; G426-V430 PolarHBondContact O-N 2.97Å; F427-V430 PolarHBondContact O-N 2.98Å; V430-S434 WeakPolarHBondContact O-CA 3.24Å; V430-S434 VanDerWaalsContact O-CB 3.26Å; V430-S434 WeakPolarHBondContact O-CB 2.99Å; V430-S434 PolarHBondContact O-N 3.21Å; V430-V435 HydrophobicContact CG1-CG2 4.31Å; V430-V435 PolarHBondContact O-N 2.98Å
431	A	93.8	Very high	91.3	Very high	0 Å²	0	32 Å²	32	0%	0	16%	0.164	C	C	.	.	I	π-helix	trans	-59.4	-51.7	178.5	0	0	0	0	0	112.4	L180 L181 F427 V435 L436	L180-A431 HydrophobicContact CB-CB 4.07Å; L180-A431 HydrophobicContact CD1-CB 4.49Å; L181-A431 HydrophobicContact CD1-CB 4.28Å; L181-A431 HydrophobicContact CD2-CB 3.9Å; L181-A431 HydrophobicContact CG-CB 3.69Å; F427-A431 WeakPolarHBondContact O-CB 3.26Å; F427-A431 PolarHBondContact O-N 3.19Å; A431-V435 WeakPolarHBondContact O-CB 3.38Å; A431-L436 WeakPolarHBondContact O-CB 3.4Å; A431-L436 WeakPolarHBondContact O-CD1 3.1Å; A431-L436 PolarHBondContact O-N 2.97Å
432	T	94.6	Very high	90.8	Very high	61 Å²	61	41.8 Å²	41.8	37%	0.374	21%	0.21	S	C	.	.	I	π-helix	trans	-80.9	-28.7	-171.9	60.9	0	0	0	0	115.1	L181 I428 Y429 L436 P437	L181-T432 HydrophobicContact CD2-CG2 4.15Å; I428-T432 HydrophobicContact CG2-CG2 4.31Å; I428-T432 VanDerWaalsContact O-CB 3.32Å; I428-T432 WeakPolarHBondContact O-CB 3.4Å; I428-T432 WeakPolarHBondContact O-CG2 3.41Å; I428-T432 PolarHBondContact O-N 3.47Å; I428-T432 PolarHBondContact O-OG1 3.43Å; Y429-T432 PolarHBondContact O-N 2.91Å; T432-L436 HydrophobicContact CG2-CD1 4.15Å; T432-P437 WeakPolarHBondContact O-CD 3.35Å
433	V	92.4	Very high	90.5	Very high	56 Å²	56	41.6 Å²	41.6	34%	0.339	22%	0.217	S	C	.	.	I	π-helix	trans	-109.3	-34.6	-173.5	-173.5	0	0	0	0	112.7	Y429	Y429-V433 HydrophobicContact CD1-CB 4.23Å; Y429-V433 HydrophobicContact CD2-CG2 3.95Å; Y429-V433 HydrophobicContact CE1-CB 3.95Å; Y429-V433 HydrophobicContact CE1-CG1 4.05Å; Y429-V433 HydrophobicContact CE1-CG2 4.38Å; Y429-V433 HydrophobicContact CE2-CB 4.24Å; Y429-V433 HydrophobicContact CE2-CG1 4.37Å; Y429-V433 HydrophobicContact CE2-CG2 3.79Å; Y429-V433 HydrophobicContact CG-CG2 4.31Å; Y429-V433 WeakPolarHBondContact O-CA 3.32Å; Y429-V433 VanDerWaalsContact O-CB 3.29Å; Y429-V433 WeakPolarHBondContact O-CB 3.44Å; Y429-V433 PolarHBondContact O-N 3.14Å
434	S	87.8	Confident	90.6	Very high	22 Å²	22	44.7 Å²	44.7	15%	0.154	24%	0.239	C	C	.	.	I	π-helix	trans	-93.3	-32.3	179.2	-61.7	0	0	0	0	113.3	V430	V430-S434 WeakPolarHBondContact O-CA 3.24Å; V430-S434 VanDerWaalsContact O-CB 3.26Å; V430-S434 WeakPolarHBondContact O-CB 2.99Å; V430-S434 PolarHBondContact O-N 3.21Å
435	V	90.6	Very high	90.6	Very high	1 Å²	1	50.2 Å²	50.2	1%	0.006	28%	0.275	C	S	.	.	I	π-helix	trans	-103.4	-62.3	-170.6	174.2	0	0	0	0	113.3	L173 I369 V430 A431 P437 E438 L439	L173-V435 HydrophobicContact CD1-CB 4.17Å; L173-V435 HydrophobicContact CD1-CG1 3.47Å; L173-V435 VanDerWaalsContact CD1-CG1 3.47Å; L173-V435 HydrophobicContact CD1-CG2 3.88Å; L173-V435 HydrophobicContact CD2-CG1 4.47Å; L173-V435 HydrophobicContact CG-CG1 3.64Å; L173-V435 WeakPolarHBondContact O-CG1 3.14Å; I369-V435 HydrophobicContact CD1-CG2 3.55Å; I369-V435 HydrophobicContact CG1-CG2 3.85Å; V430-V435 HydrophobicContact CG1-CG2 4.31Å; V430-V435 PolarHBondContact O-N 2.98Å; A431-V435 WeakPolarHBondContact O-CB 3.38Å; V435-P437 VanDerWaalsContact C-CD 3.42Å; V435-P437 VanDerWaalsContact C-N 3.3Å; V435-P437 VanDerWaalsContact O-N 3.15Å; V435-E438 VanDerWaalsContact O-CB 3.29Å; V435-E438 WeakPolarHBondContact O-CB 3.35Å; V435-E438 PolarHBondContact O-N 2.85Å; V435-L439 HydrophobicContact CG1-CD1 4.24Å
436	L	92.5	Very high	90.5	Very high	48 Å²	48	55.6 Å²	55.6	25%	0.251	30%	0.303	S	S	.	.	H	α-helix	trans	-50.1	-39.5	-177	-93.3	144.6	0	0	0	114.3	S177 L181 A431 T432 E438 L439 L440 L455	S177-L436 WeakPolarHBondContact OG-CD1 3.31Å; L181-L436 HydrophobicContact CD1-CD1 4.07Å; A431-L436 WeakPolarHBondContact O-CB 3.4Å; A431-L436 WeakPolarHBondContact O-CD1 3.1Å; A431-L436 PolarHBondContact O-N 2.97Å; T432-L436 HydrophobicContact CG2-CD1 4.15Å; L436-E438 PolarHBondContact O-N 3.22Å; L436-L439 PolarHBondContact O-N 2.97Å; L436-L440 WeakPolarHBondContact O-CG 3.3Å; L436-L440 PolarHBondContact O-N 3.36Å; L436-L455 HydrophobicContact CD2-CD1 4.28Å
437	P	91	Very high	90.5	Very high	58 Å²	58	56.8 Å²	56.8	38%	0.377	31%	0.308	S	S	.	.	H	α-helix	trans	-68.1	-15.7	177	-23.6	37	0	0	0	115.5	T432 V435	T432-P437 WeakPolarHBondContact O-CD 3.35Å; V435-P437 VanDerWaalsContact C-CD 3.42Å; V435-P437 VanDerWaalsContact C-N 3.3Å; V435-P437 VanDerWaalsContact O-N 3.15Å
438	E	87.3	Confident	90.5	Very high	29 Å²	29	58.9 Å²	58.9	14%	0.136	32%	0.323	C	S	.	.	H	α-helix	trans	-76.8	-42	170.3	-174.9	73.9	-116.5	0	0	110.6	L173 Q372 V435 L436 L440 R441	L173-E438 HydrophobicContact CD2-CB 3.93Å; L173-E438 HydrophobicContact CD2-CG 3.65Å; Q372-E438 HydrophobicContact CG-CG 4.37Å; Q372-E438 PolarHBondContact NE2-OE1 3.01Å; Q372-E438 PolarHBondContact NE2-OE2 3.12Å; V435-E438 VanDerWaalsContact O-CB 3.29Å; V435-E438 WeakPolarHBondContact O-CB 3.35Å; V435-E438 PolarHBondContact O-N 2.85Å; L436-E438 PolarHBondContact O-N 3.22Å; E438-L440 PolarHBondContact O-N 3.07Å; E438-R441 WeakPolarHBondContact O-CB 3.08Å; E438-R441 WeakPolarHBondContact O-CG 3.29Å; E438-R441 PolarHBondContact O-N 3.46Å; E438-R441 IonicContact OE1-CZ 3.78Å; E438-R441 IonicContact OE1-NH1 2.7Å; E438-R441 PolarHBondContact OE1-NH1 2.86Å; E438-R441 IonicContact OE2-NH1 2.82Å; E438-R441 PolarHBondContact OE2-NH1 3.02Å
439	L	88.7	Confident	90.3	Very high	21 Å²	21	62.7 Å²	62.7	11%	0.11	34%	0.343	C	S	.	.	H	α-helix	trans	-67.4	-21.7	177.9	-55.3	172.3	0	0	0	113.1	Q170 L173 V435 L436 R441	Q170-L439 HydrophobicContact CB-CD2 4.48Å; Q170-L439 WeakPolarHBondContact O-CD2 3.3Å; L173-L439 HydrophobicContact CB-CD2 4.28Å; L173-L439 HydrophobicContact CD2-CD2 4.16Å; L173-L439 HydrophobicContact CG-CD2 4.12Å; V435-L439 HydrophobicContact CG1-CD1 4.24Å; L436-L439 PolarHBondContact O-N 2.97Å; L439-R441 PolarHBondContact O-N 3.49Å
440	L	90	Very high	90.3	Very high	145 Å²	145	63.5 Å²	63.5	76%	0.759	35%	0.348	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.8	5.9	176.1	-67.3	175.2	0	0	0	113.9	L436 E438	L436-L440 WeakPolarHBondContact O-CG 3.3Å; L436-L440 PolarHBondContact O-N 3.36Å; E438-L440 PolarHBondContact O-N 3.07Å
441	R	86.7	Confident	90.4	Very high	145 Å²	145	64 Å²	64	55%	0.547	35%	0.351	S	S	.	.	S	Bend	trans	-78.6	165.6	175.4	-68.3	-169.7	169.4	109.4	16.2	111.8	E438 L439 A443	E438-R441 WeakPolarHBondContact O-CB 3.08Å; E438-R441 WeakPolarHBondContact O-CG 3.29Å; E438-R441 PolarHBondContact O-N 3.46Å; E438-R441 IonicContact OE1-CZ 3.78Å; E438-R441 IonicContact OE1-NH1 2.7Å; E438-R441 PolarHBondContact OE1-NH1 2.86Å; E438-R441 IonicContact OE2-NH1 2.82Å; E438-R441 PolarHBondContact OE2-NH1 3.02Å; L439-R441 PolarHBondContact O-N 3.49Å; R441-A443 PolarHBondContact O-N 3.38Å; R441-A443 VanDerWaalsContact O-N 3.09Å
442	E	80.3	Confident	90.4	Very high	206 Å²	206	67.9 Å²	67.9	96%	0.963	37%	0.374	S	S	*	.	S	Bend	trans	-57.3	113.9	-178.1	-67.3	175.8	-168.1	0	0	111.7
443	A	83.8	Confident	90.4	Very high	44 Å²	44	68.9 Å²	68.9	36%	0.364	38%	0.377	S	S	.	.			trans	-131.8	162	175.6	0	0	0	0	0	110	R441 Q447	R441-A443 PolarHBondContact O-N 3.38Å; R441-A443 VanDerWaalsContact O-N 3.09Å; A443-Q447 HydrophobicContact CB-CB 4.13Å; A443-Q447 HydrophobicContact CB-CG 3.87Å
444	S	90.5	Very high	90.4	Very high	68 Å²	68	66.3 Å²	66.3	48%	0.476	36%	0.361	S	S	.	.			trans	-69.6	152.4	171.9	71.6	0	0	0	0	110.1	L446 Q447 S448	S444-L446 PolarHBondContact O-N 3.45Å; S444-L446 VanDerWaalsContact O-N 3.14Å; S444-Q447 WeakPolarHBondContact O-CA 3.28Å; S444-Q447 WeakPolarHBondContact O-CB 3.48Å; S444-Q447 PolarHBondContact O-N 3.31Å; S444-Q447 VanDerWaalsContact OG-CB 3.31Å; S444-Q447 WeakPolarHBondContact OG-CB 3.24Å; S444-Q447 PolarHBondContact OG-N 2.97Å; S444-S448 PolarHBondContact O-N 2.87Å; S444-S448 PolarHBondContact O-OG 3.41Å
445	P	91.1	Very high	90.7	Very high	116 Å²	116	67.2 Å²	67.2	75%	0.753	36%	0.364	S	S	*	.	H	α-helix	trans	-59.7	-30.2	-176.9	22.1	-33.8	0	0	0	113.5	L449	P445-L449 WeakPolarHBondContact O-CB 3.49Å; P445-L449 PolarHBondContact O-N 3.04Å; P445-L449 VanDerWaalsContact O-N 3.09Å
446	L	91.4	Very high	90.9	Very high	114 Å²	114	71.2 Å²	71.2	60%	0.597	39%	0.385	S	S	*	.	H	α-helix	trans	-71.2	-40.1	172.6	-66.6	178.4	0	0	0	112.2	S444 L449 L450	S444-L446 PolarHBondContact O-N 3.45Å; S444-L446 VanDerWaalsContact O-N 3.14Å; L446-L449 PolarHBondContact O-N 2.85Å; L446-L450 WeakPolarHBondContact O-CG 3.49Å; L446-L450 PolarHBondContact O-N 2.59Å
447	Q	91.4	Very high	91	Very high	24 Å²	24	70.1 Å²	70.1	11%	0.112	39%	0.385	C	S	.	.	H	α-helix	trans	-63.9	-46	175.6	177.7	64.9	31.2	0	0	110.9	S167 A443 S444 L449 L450 E451	S167-Q447 PolarHBondContact O-NE2 3.19Å; S167-Q447 PolarHBondContact OG-OE1 3.33Å; A443-Q447 HydrophobicContact CB-CB 4.13Å; A443-Q447 HydrophobicContact CB-CG 3.87Å; S444-Q447 WeakPolarHBondContact O-CA 3.28Å; S444-Q447 WeakPolarHBondContact O-CB 3.48Å; S444-Q447 PolarHBondContact O-N 3.31Å; S444-Q447 VanDerWaalsContact OG-CB 3.31Å; S444-Q447 WeakPolarHBondContact OG-CB 3.24Å; S444-Q447 PolarHBondContact OG-N 2.97Å; Q447-L449 VanDerWaalsContact C-N 3.31Å; Q447-L449 PolarHBondContact O-N 3.41Å; Q447-L450 PolarHBondContact O-N 3.38Å; Q447-L450 VanDerWaalsContact O-N 3.14Å; Q447-E451 VanDerWaalsContact CG-OE1 3.26Å; Q447-E451 WeakPolarHBondContact CG-OE1 3.47Å; Q447-E451 PolarHBondContact NE2-OE1 3.44Å; Q447-E451 WeakPolarHBondContact O-CG 3.36Å; Q447-E451 PolarHBondContact O-N 3.45Å
448	S	92.5	Very high	91	Very high	46 Å²	46	67.3 Å²	67.3	32%	0.322	37%	0.367	S	S	.	.	H	α-helix	trans	-62.1	-36.3	175.1	-58	0	0	0	0	112.7	S444 E451 V452	S444-S448 PolarHBondContact O-N 2.87Å; S444-S448 PolarHBondContact O-OG 3.41Å; S448-E451 PolarHBondContact O-N 3.32Å; S448-V452 WeakPolarHBondContact O-CG2 3.46Å; S448-V452 PolarHBondContact O-N 2.97Å
449	L	93.6	Very high	91.4	Very high	98 Å²	98	68.1 Å²	68.1	51%	0.513	37%	0.374	S	S	.	.	H	α-helix	trans	-64.7	-43.7	173	178.4	62	0	0	0	111.5	P445 L446 Q447 E451 V452 L453	P445-L449 WeakPolarHBondContact O-CB 3.49Å; P445-L449 PolarHBondContact O-N 3.04Å; P445-L449 VanDerWaalsContact O-N 3.09Å; L446-L449 PolarHBondContact O-N 2.85Å; Q447-L449 VanDerWaalsContact C-N 3.31Å; Q447-L449 PolarHBondContact O-N 3.41Å; L449-E451 VanDerWaalsContact C-N 3.32Å; L449-E451 PolarHBondContact O-N 2.93Å; L449-V452 PolarHBondContact O-N 3.12Å; L449-L453 HydrophobicContact CD1-CD1 4.38Å; L449-L453 HydrophobicContact CD1-CG 4.38Å; L449-L453 HydrophobicContact CG-CD1 4.15Å; L449-L453 WeakPolarHBondContact O-CB 3.23Å; L449-L453 VanDerWaalsContact O-CG 3.26Å; L449-L453 WeakPolarHBondContact O-CG 3.18Å; L449-L453 PolarHBondContact O-N 2.98Å
450	L	93.4	Very high	91.6	Very high	30 Å²	30	72 Å²	72	16%	0.157	39%	0.394	C	S	.	.	H	α-helix	trans	-64.4	-35.3	175.9	-71.6	169.3	0	0	0	112.3	L24 I171 L446 Q447 L453 G454	L24-L450 HydrophobicContact CD2-CD2 4.43Å; I171-L450 HydrophobicContact CD1-CB 4.06Å; I171-L450 HydrophobicContact CD1-CD1 4.35Å; I171-L450 HydrophobicContact CG1-CB 4.16Å; L446-L450 WeakPolarHBondContact O-CG 3.49Å; L446-L450 PolarHBondContact O-N 2.59Å; Q447-L450 PolarHBondContact O-N 3.38Å; Q447-L450 VanDerWaalsContact O-N 3.14Å; L450-L453 PolarHBondContact O-N 2.98Å; L450-G454 PolarHBondContact O-N 3.28Å
451	E	93.8	Very high	91.5	Very high	13 Å²	13	66.5 Å²	66.5	6%	0.061	37%	0.365	C	S	.	.	H	α-helix	trans	-67.4	-45.3	174.3	-73.9	160	-173.6	0	0	111.5	Q170 I171 S174 Q447 S448 L449 L453 G454 L455	Q170-E451 HydrophobicContact CB-CG 4.18Å; Q170-E451 WeakPolarHBondContact CB-OE1 3.32Å; I171-E451 HydrophobicContact CG1-CG 4.46Å; S174-E451 WeakPolarHBondContact CB-O 3.41Å; S174-E451 WeakPolarHBondContact OG-CA 3.47Å; S174-E451 PolarHBondContact OG-O 3.13Å; Q447-E451 VanDerWaalsContact CG-OE1 3.26Å; Q447-E451 WeakPolarHBondContact CG-OE1 3.47Å; Q447-E451 PolarHBondContact NE2-OE1 3.44Å; Q447-E451 WeakPolarHBondContact O-CG 3.36Å; Q447-E451 PolarHBondContact O-N 3.45Å; S448-E451 PolarHBondContact O-N 3.32Å; L449-E451 VanDerWaalsContact C-N 3.32Å; L449-E451 PolarHBondContact O-N 2.93Å; E451-L453 VanDerWaalsContact C-N 3.33Å; E451-L453 PolarHBondContact O-N 3.27Å; E451-G454 PolarHBondContact O-N 2.86Å; E451-L455 PolarHBondContact O-N 2.9Å
452	V	94.3	Very high	91.7	Very high	81 Å²	81	59.7 Å²	59.7	49%	0.491	34%	0.339	S	S	.	.	H	α-helix	trans	-61.4	-41.3	173.4	171.1	0	0	0	0	111.2	S448 L449 L455 L456	S448-V452 WeakPolarHBondContact O-CG2 3.46Å; S448-V452 PolarHBondContact O-N 2.97Å; L449-V452 PolarHBondContact O-N 3.12Å; V452-L455 PolarHBondContact O-N 3.01Å; V452-L456 HydrophobicContact CG1-CD1 4.11Å; V452-L456 HydrophobicContact CG1-CG 4.5Å; V452-L456 WeakPolarHBondContact O-CB 3.16Å; V452-L456 VanDerWaalsContact O-CG 3.32Å; V452-L456 WeakPolarHBondContact O-CG 3.27Å; V452-L456 PolarHBondContact O-N 2.8Å
453	L	94.8	Very high	92.2	Very high	82 Å²	82	52.5 Å²	52.5	43%	0.429	31%	0.309	S	S	.	.	H	α-helix	trans	-66.1	-35.1	174.5	-71.6	173	0	0	0	112.5	L449 L450 E451 G457	L449-L453 HydrophobicContact CD1-CD1 4.38Å; L449-L453 HydrophobicContact CD1-CG 4.38Å; L449-L453 HydrophobicContact CG-CD1 4.15Å; L449-L453 WeakPolarHBondContact O-CB 3.23Å; L449-L453 VanDerWaalsContact O-CG 3.26Å; L449-L453 WeakPolarHBondContact O-CG 3.18Å; L449-L453 PolarHBondContact O-N 2.98Å; L450-L453 PolarHBondContact O-N 2.98Å; E451-L453 VanDerWaalsContact C-N 3.33Å; E451-L453 PolarHBondContact O-N 3.27Å; L453-G457 PolarHBondContact O-N 3.29Å
454	G	93.1	Very high	92.4	Very high	1 Å²	1	54.5 Å²	54.5	1%	0.01	31%	0.313	C	S	.	.	H	α-helix	trans	-63.9	-47.2	173	0	0	0	0	0	111.8	S174 F175 L450 E451 G457 G458	S174-G454 WeakPolarHBondContact OG-CA 3.45Å; F175-G454 VanDerWaalsContact CA-O 3.31Å; F175-G454 WeakPolarHBondContact CA-O 3.45Å; L450-G454 PolarHBondContact O-N 3.28Å; E451-G454 PolarHBondContact O-N 2.86Å; G454-G457 CarbonylContact O-C 3.54Å; G454-G457 WeakPolarHBondContact O-CA 3.32Å; G454-G457 PolarHBondContact O-N 3.35Å; G454-G457 VanDerWaalsContact O-N 3.08Å; G454-G458 PolarHBondContact O-N 3.25Å
455	L	94.3	Very high	92.1	Very high	41 Å²	41	51.7 Å²	51.7	22%	0.215	29%	0.293	C	S	.	.	H	α-helix	trans	-61.4	-47.4	176	-173.8	156.6	0	0	0	111.6	S174 G178 L436 E451 V452 G457 G458 V459	S174-L455 WeakPolarHBondContact O-CA 3.28Å; S174-L455 WeakPolarHBondContact O-CB 3.43Å; S174-L455 PolarHBondContact OG-N 2.99Å; G178-L455 WeakPolarHBondContact CA-O 3.41Å; L436-L455 HydrophobicContact CD2-CD1 4.28Å; E451-L455 PolarHBondContact O-N 2.9Å; V452-L455 PolarHBondContact O-N 3.01Å; L455-G457 PolarHBondContact O-N 2.75Å; L455-G458 PolarHBondContact O-N 3Å; L455-V459 HydrophobicContact CD2-CG2 4.28Å; L455-V459 WeakPolarHBondContact O-CG2 3.35Å; L455-V459 PolarHBondContact O-N 3.45Å
456	L	95.3	Very high	91.7	Very high	85 Å²	85	47.8 Å²	47.8	45%	0.445	27%	0.27	S	S	.	.	H	α-helix	trans	-61.3	-35.6	173	-70	174.3	0	0	0	111.7	V452 V459 I460	V452-L456 HydrophobicContact CG1-CD1 4.11Å; V452-L456 HydrophobicContact CG1-CG 4.5Å; V452-L456 WeakPolarHBondContact O-CB 3.16Å; V452-L456 VanDerWaalsContact O-CG 3.32Å; V452-L456 WeakPolarHBondContact O-CG 3.27Å; V452-L456 PolarHBondContact O-N 2.8Å; L456-V459 PolarHBondContact O-N 2.77Å; L456-I460 VanDerWaalsContact O-CB 3.28Å; L456-I460 WeakPolarHBondContact O-CB 3.49Å; L456-I460 WeakPolarHBondContact O-CD1 3.45Å; L456-I460 WeakPolarHBondContact O-CG1 3.2Å; L456-I460 PolarHBondContact O-N 2.81Å
457	G	93	Very high	91.4	Very high	25 Å²	25	49.4 Å²	49.4	26%	0.258	28%	0.275	S	S	.	.	H	α-helix	trans	-60	-43.8	173.4	0	0	0	0	0	112.9	L453 G454 L455 M461	L453-G457 PolarHBondContact O-N 3.29Å; G454-G457 CarbonylContact O-C 3.54Å; G454-G457 WeakPolarHBondContact O-CA 3.32Å; G454-G457 PolarHBondContact O-N 3.35Å; G454-G457 VanDerWaalsContact O-N 3.08Å; L455-G457 PolarHBondContact O-N 2.75Å; G457-M461 VanDerWaalsContact O-CB 3.23Å; G457-M461 WeakPolarHBondContact O-CB 3.49Å; G457-M461 PolarHBondContact O-N 2.89Å
458	G	92.6	Very high	90.6	Very high	0 Å²	0	52.2 Å²	52.2	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-63.1	-45.7	174.5	0	0	0	0	0	112.4	G454 L455 M461 M462	G454-G458 PolarHBondContact O-N 3.25Å; L455-G458 PolarHBondContact O-N 3Å; G458-M461 PolarHBondContact O-N 3.13Å; G458-M462 PolarHBondContact O-N 3.39Å
459	V	93.8	Very high	89.4	Confident	45 Å²	45	55.6 Å²	55.6	27%	0.273	30%	0.3	S	S	.	.	H	α-helix	trans	-63.6	-47.8	176.4	177.4	0	0	0	0	111.4	G178 L455 L456 M461 M462 V463	G178-V459 WeakPolarHBondContact O-CG2 3.34Å; G178-V459 PolarHBondContact O-N 2.78Å; L455-V459 HydrophobicContact CD2-CG2 4.28Å; L455-V459 WeakPolarHBondContact O-CG2 3.35Å; L455-V459 PolarHBondContact O-N 3.45Å; L456-V459 PolarHBondContact O-N 2.77Å; V459-M461 PolarHBondContact O-N 3.41Å; V459-M462 PolarHBondContact O-N 3.36Å; V459-V463 HydrophobicContact CG1-CG2 4.48Å; V459-V463 WeakPolarHBondContact O-CG2 3.46Å; V459-V463 PolarHBondContact O-N 2.96Å
460	I	92.9	Very high	89.2	Confident	103 Å²	103	53.5 Å²	53.5	53%	0.528	29%	0.29	S	S	.	.	H	α-helix	trans	-59.7	-39.1	178.2	-72.8	164.4	0	0	0	110.6	L456 V463 L464	L456-I460 VanDerWaalsContact O-CB 3.28Å; L456-I460 WeakPolarHBondContact O-CB 3.49Å; L456-I460 WeakPolarHBondContact O-CD1 3.45Å; L456-I460 WeakPolarHBondContact O-CG1 3.2Å; L456-I460 PolarHBondContact O-N 2.81Å; I460-V463 WeakPolarHBondContact O-CB 3.48Å; I460-V463 PolarHBondContact O-N 2.81Å; I460-L464 HydrophobicContact CG2-CD1 4.22Å; I460-L464 HydrophobicContact CG2-CG 4.47Å; I460-L464 VanDerWaalsContact O-CG 3.31Å; I460-L464 WeakPolarHBondContact O-CG 3.47Å; I460-L464 PolarHBondContact O-N 3.39Å
461	M	89.8	Confident	89	Confident	29 Å²	29	54.7 Å²	54.7	14%	0.143	30%	0.297	C	S	.	.	H	α-helix	trans	-65.4	-43.7	176.8	-177.6	-140.7	74.3	0	0	111.7	F175 P361 G457 G458 V459 V463 L464 I465	F175-M461 HydrophobicContact CE2-SD 4.36Å; F175-M461 HydrophobicContact CZ-SD 3.64Å; P361-M461 HydrophobicContact CB-CE 3.53Å; P361-M461 HydrophobicContact CB-SD 3.27Å; P361-M461 WeakPolarHBondContact CB-SD 3.39Å; P361-M461 HydrophobicContact CG-CE 3.73Å; P361-M461 HydrophobicContact CG-SD 3.13Å; P361-M461 WeakPolarHBondContact CG-SD 3.37Å; G457-M461 VanDerWaalsContact O-CB 3.23Å; G457-M461 WeakPolarHBondContact O-CB 3.49Å; G457-M461 PolarHBondContact O-N 2.89Å; G458-M461 PolarHBondContact O-N 3.13Å; V459-M461 PolarHBondContact O-N 3.41Å; M461-V463 VanDerWaalsContact C-N 3.33Å; M461-V463 PolarHBondContact O-N 3.47Å; M461-L464 WeakPolarHBondContact O-CB 3.34Å; M461-L464 PolarHBondContact O-N 3.28Å; M461-L464 VanDerWaalsContact O-N 3.11Å; M461-I465 HydrophobicContact CE-CD1 3.84Å; M461-I465 HydrophobicContact CG-CD1 4.34Å; M461-I465 WeakPolarHBondContact O-CG1 3.26Å; M461-I465 PolarHBondContact O-N 2.87Å; M461-I465 HydrophobicContact SD-CD1 4.45Å
462	M	89.9	Confident	88.7	Confident	3 Å²	3	57 Å²	57	2%	0.015	31%	0.31	C	S	.	.	H	α-helix	trans	-63.6	-37.4	172.8	-67.7	-50.9	-54.7	0	0	112.4	G179 D183 L186 H358 G458 V459 L464 I465 A466	G179-M462 WeakPolarHBondContact O-CG 3.04Å; D183-M462 HydrophobicContact CB-CE 3.81Å; D183-M462 HydrophobicContact CB-SD 4.42Å; L186-M462 HydrophobicContact CD1-CB 4.41Å; H358-M462 HydrophobicContact CB-CE 4Å; H358-M462 HydrophobicContact CB-SD 4.2Å; G458-M462 PolarHBondContact O-N 3.39Å; V459-M462 PolarHBondContact O-N 3.36Å; M462-L464 VanDerWaalsContact C-N 3.31Å; M462-L464 PolarHBondContact O-N 3Å; M462-I465 PolarHBondContact O-N 3Å; M462-I465 HydrophobicContact SD-CD1 4.24Å; M462-A466 WeakPolarHBondContact O-CB 3.29Å; M462-A466 PolarHBondContact O-N 3.02Å
463	V	91.2	Very high	88.4	Confident	55 Å²	55	55.6 Å²	55.6	33%	0.333	30%	0.299	S	S	.	.	H	α-helix	trans	-58.1	-43.8	170.7	172.8	0	0	0	0	110.9	L186 V459 I460 M461 A466 H467	L186-V463 HydrophobicContact CD1-CB 4.43Å; L186-V463 HydrophobicContact CD1-CG2 3.44Å; L186-V463 VanDerWaalsContact CD1-CG2 3.44Å; V459-V463 HydrophobicContact CG1-CG2 4.48Å; V459-V463 WeakPolarHBondContact O-CG2 3.46Å; V459-V463 PolarHBondContact O-N 2.96Å; I460-V463 WeakPolarHBondContact O-CB 3.48Å; I460-V463 PolarHBondContact O-N 2.81Å; M461-V463 VanDerWaalsContact C-N 3.33Å; M461-V463 PolarHBondContact O-N 3.47Å; V463-A466 PolarHBondContact O-N 2.89Å; V463-H467 PolarHBondContact O-N 3.45Å; V463-H467 PolarHBondContact O-ND1 3.36Å
464	L	88.8	Confident	88	Confident	86 Å²	86	53.9 Å²	53.9	45%	0.45	29%	0.291	S	S	.	.	H	α-helix	trans	-65.5	-38.1	178.7	-71.5	170.9	0	0	0	112.2	I460 M461 M462 H467 L468	I460-L464 HydrophobicContact CG2-CD1 4.22Å; I460-L464 HydrophobicContact CG2-CG 4.47Å; I460-L464 VanDerWaalsContact O-CG 3.31Å; I460-L464 WeakPolarHBondContact O-CG 3.47Å; I460-L464 PolarHBondContact O-N 3.39Å; M461-L464 WeakPolarHBondContact O-CB 3.34Å; M461-L464 PolarHBondContact O-N 3.28Å; M461-L464 VanDerWaalsContact O-N 3.11Å; M462-L464 VanDerWaalsContact C-N 3.31Å; M462-L464 PolarHBondContact O-N 3Å; L464-H467 PolarHBondContact O-N 3.27Å; L464-L468 WeakPolarHBondContact O-CG 3.48Å; L464-L468 PolarHBondContact O-N 3.11Å
465	I	83.8	Confident	87.6	Confident	9 Å²	9	57.5 Å²	57.5	5%	0.046	31%	0.31	C	S	.	.	H	α-helix	trans	-68.6	-43.7	177.1	-64.5	172.2	0	0	0	110.8	L357 H358 M461 M462 H467 L468 E469	L357-I465 HydrophobicContact CB-CD1 4.39Å; L357-I465 HydrophobicContact CB-CG1 4.5Å; L357-I465 WeakPolarHBondContact O-CD1 3.19Å; H358-I465 HydrophobicContact CB-CD1 3.76Å; H358-I465 HydrophobicContact CB-CG2 4.36Å; M461-I465 HydrophobicContact CE-CD1 3.84Å; M461-I465 HydrophobicContact CG-CD1 4.34Å; M461-I465 WeakPolarHBondContact O-CG1 3.26Å; M461-I465 PolarHBondContact O-N 2.87Å; M461-I465 HydrophobicContact SD-CD1 4.45Å; M462-I465 PolarHBondContact O-N 3Å; M462-I465 HydrophobicContact SD-CD1 4.24Å; I465-H467 PolarHBondContact O-N 3.29Å; I465-L468 WeakPolarHBondContact O-CA 3.49Å; I465-L468 WeakPolarHBondContact O-CB 3.41Å; I465-L468 PolarHBondContact O-N 3.03Å; I465-E469 PolarHBondContact O-N 2.9Å
466	A	83.1	Confident	87.2	Confident	34 Å²	34	58.6 Å²	58.6	28%	0.281	32%	0.317	S	S	.	.	T	Hydrogen-bonded Turn	trans	-65.1	-5.2	173.9	0	0	0	0	0	114.5	M462 V463	M462-A466 WeakPolarHBondContact O-CB 3.29Å; M462-A466 PolarHBondContact O-N 3.02Å; V463-A466 PolarHBondContact O-N 2.89Å
467	H	83.8	Confident	86.5	Confident	148 Å²	148	56.6 Å²	56.6	69%	0.685	31%	0.307	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101	-7.3	168.5	-76.6	70.6	0	0	0	113.5	V463 L464 I465	V463-H467 PolarHBondContact O-N 3.45Å; V463-H467 PolarHBondContact O-ND1 3.36Å; L464-H467 PolarHBondContact O-N 3.27Å; I465-H467 PolarHBondContact O-N 3.29Å
468	L	74.4	Confident	86	Confident	83 Å²	83	59.3 Å²	59.3	44%	0.435	31%	0.311	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.6	-21.1	174.3	-65.4	173.3	0	0	0	112.3	L357 L464 I465	L357-L468 HydrophobicContact CD1-CD1 4.02Å; L464-L468 WeakPolarHBondContact O-CG 3.48Å; L464-L468 PolarHBondContact O-N 3.11Å; I465-L468 WeakPolarHBondContact O-CA 3.49Å; I465-L468 WeakPolarHBondContact O-CB 3.41Å; I465-L468 PolarHBondContact O-N 3.03Å
469	E	68	Low	85.4	Confident	116 Å²	116	64.6 Å²	64.6	54%	0.542	34%	0.339	S	S	.	.			trans	-70.8	0	169.2	-71.8	165.3	-179.5	0	0	112.5	H187 T354 H358 I465	H187-E469 VanDerWaalsContact CE1-CD 3.44Å; H187-E469 IonicContact CE1-OE1 3.71Å; H187-E469 PolarHBondContact CE1-OE1 3.4Å; H187-E469 IonicContact CE1-OE2 3.79Å; H187-E469 PolarHBondContact CE1-OE2 2.92Å; H187-E469 VanDerWaalsContact CE1-OE2 3.32Å; H187-E469 IonicContact CG-OE2 3.61Å; H187-E469 VanDerWaalsContact ND1-CD 3.31Å; H187-E469 IonicContact ND1-OE1 3.76Å; H187-E469 PolarHBondContact ND1-OE1 3.38Å; H187-E469 IonicContact ND1-OE2 3.21Å; H187-E469 PolarHBondContact ND1-OE2 3.47Å; T354-E469 HydrophobicContact CG2-CG 3.4Å; T354-E469 WeakPolarHBondContact CG2-OE1 3.07Å; H358-E469 IonicContact ND1-OE1 3.4Å; I465-E469 PolarHBondContact O-N 2.9Å

Retrieved 469 of 469 residues in 1305.4 ms (Link to these results)

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