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Zinc transporter SLC39A7

Transports Zn(2+) from the endoplasmic reticulum (ER)/Golgi apparatus to the cytosol, playing an essential role in the regulation of cytosolic zinc levels^1,2,3,4. Acts as a gatekeeper of zinc release from intracellular stores, requiring post-translational activation by phosphorylation, resulting in activation of multiple downstream pathways leading to cell growth and proliferation^5,6,7. Has an essential role in B cell development and is required for proper B cell receptor signaling⁸. Plays an important role in maintaining intestinal epithelial homeostasis and skin dermis development by regulating ER function (By similarity). Controls cell signaling pathways involved in glucose metabolism in skeletal muscle (By similarity). Has a protective role against ER stress in different biological contexts^9,10. Mediates Zn(2+)-induced ferroptosis¹¹.

AlphaFold DB , UniProt , Accession Q92504, Species HUMAN (Homo sapiens, Human), Gene SLC39A7, Length 469 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	40.6	Very low	45.7	Very low	253 Å²	253	116.2 Å²	116.2	100%	1.246	66%	0.66	S	S	*	*				0	49.2	0	-66.3	172.9	172.4	0	0	111.3
2	A	44.6	Very low	46.2	Very low	76 Å²	76	110.8 Å²	110.8	63%	0.628	64%	0.641	S	S	*	*			trans	-130.8	19.4	-173.8	0	0	0	0	0	114	G4	A2-G4 PolarHBondContact O-N 3.18Å
3	R	42	Very low	47	Very low	261 Å²	261	107.2 Å²	107.2	99%	0.985	62%	0.621	S	S	*	*	T	Hydrogen-bonded Turn	trans	-86.1	99.3	170.8	-71.5	-177.5	176.6	172	-2.3	108.5
4	G	48.6	Very low	47.3	Very low	79 Å²	79	101.9 Å²	101.9	81%	0.814	60%	0.601	S	S	*	*	T	Hydrogen-bonded Turn	trans	157.3	-11.9	176	0	0	0	0	0	117.4	A2 G6	A2-G4 PolarHBondContact O-N 3.18Å; G4-G6 PolarHBondContact O-N 3.46Å
5	L	42.4	Very low	47.8	Very low	95 Å²	95	102.7 Å²	102.7	50%	0.497	60%	0.601	S	S	.	*			trans	-87.6	106.3	176.2	-75.3	160.2	0	0	0	110	H9 W10	L5-H9 HydrophobicContact CB-CB 4.42Å; L5-H9 HydrophobicContact CD2-CB 4.18Å; L5-W10 PolarHBondContact O-NE1 3.33Å
6	G	43.6	Very low	48.5	Very low	42 Å²	42	103.3 Å²	103.3	43%	0.433	60%	0.6	S	S	.	*			trans	-67.1	157.4	179.8	0	0	0	0	0	113.6	G4 P8 H9	G4-G6 PolarHBondContact O-N 3.46Å; G6-P8 WeakPolarHBondContact O-CD 3.41Å; G6-H9 PolarHBondContact O-N 2.82Å
7	A	46.7	Very low	49.3	Very low	76 Å²	76	101.5 Å²	101.5	63%	0.628	59%	0.591	S	S	*	*	T	Hydrogen-bonded Turn	trans	-35.8	-46.2	-175.7	0	0	0	0	0	117.9	H9 W10 V11	A7-H9 PolarHBondContact O-N 3.12Å; A7-H9 VanDerWaalsContact O-N 3.13Å; A7-W10 PolarHBondContact O-N 2.93Å; A7-W10 VanDerWaalsContact O-N 3.08Å; A7-V11 PolarHBondContact O-N 3.34Å
8	P	53.2	Low	49.8	Very low	98 Å²	98	101.2 Å²	101.2	64%	0.636	58%	0.578	S	S	*	*	H	α-helix	trans	-60.2	-25.5	-179.9	22.6	-35.3	0	0	0	114.3	G6 A12	G6-P8 WeakPolarHBondContact O-CD 3.41Å; P8-A12 WeakPolarHBondContact O-CB 3.14Å; P8-A12 PolarHBondContact O-N 3.47Å; P8-A12 VanDerWaalsContact O-N 3.08Å
9	H	46	Very low	50.3	Low	109 Å²	109	98.6 Å²	98.6	51%	0.505	57%	0.571	S	S	.	*	H	α-helix	trans	-70	-30.7	176.6	-85.5	-78.3	0	0	0	113.1	L5 G6 A7 A12 V13	L5-H9 HydrophobicContact CB-CB 4.42Å; L5-H9 HydrophobicContact CD2-CB 4.18Å; G6-H9 PolarHBondContact O-N 2.82Å; A7-H9 PolarHBondContact O-N 3.12Å; A7-H9 VanDerWaalsContact O-N 3.13Å; H9-A12 PolarHBondContact O-N 2.99Å; H9-V13 VanDerWaalsContact O-CG2 3.29Å; H9-V13 WeakPolarHBondContact O-CG2 3.42Å; H9-V13 PolarHBondContact O-N 3.28Å
10	W	47.9	Very low	50.9	Low	113 Å²	113	97.8 Å²	97.8	43%	0.428	57%	0.567	S	S	.	*	H	α-helix	trans	-78.5	-37.2	-179.5	-67	108.5	0	0	0	112.4	L5 A7 A12 V13 G14	L5-W10 PolarHBondContact O-NE1 3.33Å; A7-W10 PolarHBondContact O-N 2.93Å; A7-W10 VanDerWaalsContact O-N 3.08Å; W10-A12 VanDerWaalsContact C-N 3.29Å; W10-A12 PolarHBondContact O-N 3.46Å; W10-V13 HydrophobicContact CE3-CB 4.35Å; W10-V13 HydrophobicContact CE3-CG1 4.42Å; W10-V13 PolarHBondContact O-N 2.78Å; W10-V13 VanDerWaalsContact O-N 3.14Å; W10-G14 PolarHBondContact O-N 3.22Å
11	V	47.5	Very low	51.3	Low	76 Å²	76	95.9 Å²	95.9	46%	0.461	56%	0.555	S	S	.	*	H	α-helix	trans	-60.6	-42.2	167.8	-179.1	0	0	0	0	110.1	A7 V13 G14 L15	A7-V11 PolarHBondContact O-N 3.34Å; V11-V13 VanDerWaalsContact C-N 3.35Å; V11-V13 PolarHBondContact O-N 3.31Å; V11-G14 PolarHBondContact O-N 3.34Å; V11-L15 HydrophobicContact CG1-CD1 3.97Å; V11-L15 HydrophobicContact CG1-CG 4.43Å; V11-L15 WeakPolarHBondContact O-CB 3.44Å; V11-L15 VanDerWaalsContact O-CG 3.32Å; V11-L15 WeakPolarHBondContact O-CG 3.48Å; V11-L15 PolarHBondContact O-N 3.38Å
12	A	51.4	Low	52.1	Low	52 Å²	52	85.8 Å²	85.8	43%	0.43	52%	0.516	S	S	.	.	H	α-helix	trans	-63.2	-37.7	173.3	0	0	0	0	0	112.6	P8 H9 W10 L16	P8-A12 WeakPolarHBondContact O-CB 3.14Å; P8-A12 PolarHBondContact O-N 3.47Å; P8-A12 VanDerWaalsContact O-N 3.08Å; H9-A12 PolarHBondContact O-N 2.99Å; W10-A12 VanDerWaalsContact C-N 3.29Å; W10-A12 PolarHBondContact O-N 3.46Å; A12-L16 WeakPolarHBondContact O-CB 3.33Å; A12-L16 PolarHBondContact O-N 3.09Å
13	V	56.4	Low	52.8	Low	63 Å²	63	88.7 Å²	88.7	38%	0.382	52%	0.52	S	S	.	.	H	α-helix	trans	-66.2	-44.5	174.5	166.8	0	0	0	0	111.5	H9 W10 V11 L16 T17	H9-V13 VanDerWaalsContact O-CG2 3.29Å; H9-V13 WeakPolarHBondContact O-CG2 3.42Å; H9-V13 PolarHBondContact O-N 3.28Å; W10-V13 HydrophobicContact CE3-CB 4.35Å; W10-V13 HydrophobicContact CE3-CG1 4.42Å; W10-V13 PolarHBondContact O-N 2.78Å; W10-V13 VanDerWaalsContact O-N 3.14Å; V11-V13 VanDerWaalsContact C-N 3.35Å; V11-V13 PolarHBondContact O-N 3.31Å; V13-L16 CarbonylContact O-C 3.58Å; V13-L16 PolarHBondContact O-N 3.14Å; V13-T17 WeakPolarHBondContact O-CG2 3.26Å; V13-T17 PolarHBondContact O-N 2.92Å; V13-T17 PolarHBondContact O-OG1 2.86Å
14	G	51.8	Low	53.5	Low	33 Å²	33	80 Å²	80	34%	0.34	49%	0.493	S	S	.	.	H	α-helix	trans	-64.3	-41.2	177	0	0	0	0	0	113.2	W10 V11 L16 T17 W18	W10-G14 PolarHBondContact O-N 3.22Å; V11-G14 PolarHBondContact O-N 3.34Å; G14-L16 VanDerWaalsContact C-N 3.34Å; G14-T17 WeakPolarHBondContact CA-OG1 3.38Å; G14-T17 PolarHBondContact O-OG1 3.31Å; G14-W18 WeakPolarHBondContact O-CB 3.31Å; G14-W18 PolarHBondContact O-N 2.94Å; G14-W18 VanDerWaalsContact O-N 3.09Å
15	L	54.4	Low	53.8	Low	115 Å²	115	77.8 Å²	77.8	60%	0.602	46%	0.463	S	S	*	.	H	α-helix	trans	-69.2	-32	172.5	-69.3	173.7	0	0	0	112.2	V11 W18 A19	V11-L15 HydrophobicContact CG1-CD1 3.97Å; V11-L15 HydrophobicContact CG1-CG 4.43Å; V11-L15 WeakPolarHBondContact O-CB 3.44Å; V11-L15 VanDerWaalsContact O-CG 3.32Å; V11-L15 WeakPolarHBondContact O-CG 3.48Å; V11-L15 PolarHBondContact O-N 3.38Å; L15-W18 WeakPolarHBondContact O-CB 3.42Å; L15-A19 WeakPolarHBondContact O-CB 3.46Å; L15-A19 PolarHBondContact O-N 3.09Å
16	L	59.1	Low	54.3	Low	111 Å²	111	75.4 Å²	75.4	58%	0.581	46%	0.457	S	S	*	.	H	α-helix	trans	-73.9	-40.6	176.5	-171.6	71.8	0	0	0	111.4	A12 V13 G14 W18 A19 T20	A12-L16 WeakPolarHBondContact O-CB 3.33Å; A12-L16 PolarHBondContact O-N 3.09Å; V13-L16 CarbonylContact O-C 3.58Å; V13-L16 PolarHBondContact O-N 3.14Å; G14-L16 VanDerWaalsContact C-N 3.34Å; L16-W18 VanDerWaalsContact C-N 3.29Å; L16-W18 PolarHBondContact O-N 2.94Å; L16-A19 PolarHBondContact O-N 3.14Å; L16-T20 WeakPolarHBondContact O-CG2 3.37Å; L16-T20 PolarHBondContact O-N 3.14Å; L16-T20 PolarHBondContact O-OG1 2.81Å; L16-T20 VanDerWaalsContact O-OG1 3.14Å
17	T	61.1	Low	54.4	Low	73 Å²	73	75.8 Å²	75.8	45%	0.448	46%	0.461	S	S	.	.	H	α-helix	trans	-60.6	-43.3	172.3	49.4	0	0	0	0	110	V13 G14 T20 L21	V13-T17 WeakPolarHBondContact O-CG2 3.26Å; V13-T17 PolarHBondContact O-N 2.92Å; V13-T17 PolarHBondContact O-OG1 2.86Å; G14-T17 WeakPolarHBondContact CA-OG1 3.38Å; G14-T17 PolarHBondContact O-OG1 3.31Å; T17-T20 WeakPolarHBondContact CA-OG1 3.23Å; T17-T20 PolarHBondContact O-N 2.95Å; T17-T20 PolarHBondContact O-OG1 3.37Å; T17-L21 WeakPolarHBondContact O-CB 3.3Å; T17-L21 PolarHBondContact O-N 3.43Å
18	W	59.4	Low	54.7	Low	96 Å²	96	77.1 Å²	77.1	36%	0.364	46%	0.457	S	S	.	.	H	α-helix	trans	-55.7	-50.3	169.5	-106.2	88.2	0	0	0	113.7	G14 L15 L16 T20 L21 G22 L172 V364	G14-W18 WeakPolarHBondContact O-CB 3.31Å; G14-W18 PolarHBondContact O-N 2.94Å; G14-W18 VanDerWaalsContact O-N 3.09Å; L15-W18 WeakPolarHBondContact O-CB 3.42Å; L16-W18 VanDerWaalsContact C-N 3.29Å; L16-W18 PolarHBondContact O-N 2.94Å; W18-T20 VanDerWaalsContact C-N 3.32Å; W18-T20 PolarHBondContact O-N 2.65Å; W18-L21 PolarHBondContact O-N 3.29Å; W18-G22 PolarHBondContact O-N 2.79Å; W18-L172 HydrophobicContact CH2-CD2 4.42Å; W18-V364 HydrophobicContact CH2-CG1 3.75Å; W18-V364 HydrophobicContact CH2-CG2 4.18Å; W18-V364 HydrophobicContact CZ2-CB 4.42Å; W18-V364 HydrophobicContact CZ2-CG1 3.89Å; W18-V364 HydrophobicContact CZ2-CG2 4.18Å
19	A	59.4	Low	54.4	Low	53 Å²	53	75.2 Å²	75.2	44%	0.438	46%	0.455	S	S	.	.	H	α-helix	trans	-62.3	-39.3	178.2	0	0	0	0	0	111.7	L15 L16 L23	L15-A19 WeakPolarHBondContact O-CB 3.46Å; L15-A19 PolarHBondContact O-N 3.09Å; L16-A19 PolarHBondContact O-N 3.14Å; A19-L23 WeakPolarHBondContact O-CB 3.39Å; A19-L23 PolarHBondContact O-N 2.82Å
20	T	61.3	Low	54.2	Low	81 Å²	81	72.8 Å²	72.8	50%	0.497	46%	0.46	S	S	.	.	H	α-helix	trans	-70.2	-39.3	176.9	57.7	0	0	0	0	112.6	L16 T17 W18 L23 L24	L16-T20 WeakPolarHBondContact O-CG2 3.37Å; L16-T20 PolarHBondContact O-N 3.14Å; L16-T20 PolarHBondContact O-OG1 2.81Å; L16-T20 VanDerWaalsContact O-OG1 3.14Å; T17-T20 WeakPolarHBondContact CA-OG1 3.23Å; T17-T20 PolarHBondContact O-N 2.95Å; T17-T20 PolarHBondContact O-OG1 3.37Å; W18-T20 VanDerWaalsContact C-N 3.32Å; W18-T20 PolarHBondContact O-N 2.65Å; T20-L23 PolarHBondContact O-N 3.35Å; T20-L24 VanDerWaalsContact O-CB 3.23Å; T20-L24 WeakPolarHBondContact O-CB 3.35Å; T20-L24 PolarHBondContact O-N 2.85Å
21	L	60.8	Low	54.2	Low	59 Å²	59	75.5 Å²	75.5	31%	0.309	48%	0.477	S	S	.	.	H	α-helix	trans	-65.4	-44.5	174.5	-173	66.2	0	0	0	110.4	T17 W18 L23 L24 V25	T17-L21 WeakPolarHBondContact O-CB 3.3Å; T17-L21 PolarHBondContact O-N 3.43Å; W18-L21 PolarHBondContact O-N 3.29Å; L21-L23 PolarHBondContact O-N 3.27Å; L21-L24 PolarHBondContact O-N 2.95Å; L21-V25 WeakPolarHBondContact O-CB 3.33Å; L21-V25 VanDerWaalsContact O-CG2 3.3Å; L21-V25 WeakPolarHBondContact O-CG2 3.49Å; L21-V25 PolarHBondContact O-N 3.08Å
22	G	55.7	Low	54.2	Low	41 Å²	41	78.2 Å²	78.2	42%	0.423	49%	0.489	S	S	.	.	H	α-helix	trans	-59.4	-42.2	173.3	0	0	0	0	0	113.1	W18 A26	W18-G22 PolarHBondContact O-N 2.79Å; G22-A26 WeakPolarHBondContact O-CB 3.37Å; G22-A26 PolarHBondContact O-N 2.85Å
23	L	59.1	Low	54	Low	136 Å²	136	83 Å²	83	71%	0.712	51%	0.507	S	S	*	.	H	α-helix	trans	-69.5	-38.5	175	-121.2	79.9	0	0	0	112.7	A19 T20 L21 A26 G27	A19-L23 WeakPolarHBondContact O-CB 3.39Å; A19-L23 PolarHBondContact O-N 2.82Å; T20-L23 PolarHBondContact O-N 3.35Å; L21-L23 PolarHBondContact O-N 3.27Å; L23-A26 PolarHBondContact O-N 3.46Å; L23-G27 WeakPolarHBondContact O-CA 3.37Å; L23-G27 PolarHBondContact O-N 3.22Å
24	L	57.9	Low	53.3	Low	80 Å²	80	87.5 Å²	87.5	42%	0.419	53%	0.528	S	S	.	.	H	α-helix	trans	-63.6	-48.5	179.1	-167.5	83.1	0	0	0	110.2	T20 L21 A26 G27 L28 L450	T20-L24 VanDerWaalsContact O-CB 3.23Å; T20-L24 WeakPolarHBondContact O-CB 3.35Å; T20-L24 PolarHBondContact O-N 2.85Å; L21-L24 PolarHBondContact O-N 2.95Å; L24-A26 VanDerWaalsContact C-N 3.32Å; L24-A26 PolarHBondContact O-N 2.88Å; L24-G27 PolarHBondContact O-N 3.2Å; L24-L28 HydrophobicContact CD1-CD1 4.08Å; L24-L28 HydrophobicContact CD1-CG 4.49Å; L24-L28 HydrophobicContact CD2-CD1 4.37Å; L24-L28 HydrophobicContact CG-CD1 3.8Å; L24-L28 HydrophobicContact CG-CG 4.4Å; L24-L28 WeakPolarHBondContact O-CB 3.45Å; L24-L28 WeakPolarHBondContact O-CG 3.49Å; L24-L28 PolarHBondContact O-N 2.96Å; L24-L450 HydrophobicContact CD2-CD2 4.43Å
25	V	53.9	Low	53.1	Low	31 Å²	31	94 Å²	94	19%	0.188	55%	0.549	C	S	.	.	H	α-helix	trans	-65.6	-34	175.4	174.7	0	0	0	0	111.5	L21 L168 I171	L21-V25 WeakPolarHBondContact O-CB 3.33Å; L21-V25 VanDerWaalsContact O-CG2 3.3Å; L21-V25 WeakPolarHBondContact O-CG2 3.49Å; L21-V25 PolarHBondContact O-N 3.08Å; V25-L168 HydrophobicContact CG1-CD1 4.3Å; V25-I171 HydrophobicContact CG1-CD1 4.04Å; V25-I171 HydrophobicContact CG2-CD1 3.99Å
26	A	54.4	Low	52.6	Low	46 Å²	46	94.2 Å²	94.2	38%	0.38	55%	0.551	S	S	.	*	H	α-helix	trans	-77.6	-27.1	176.3	0	0	0	0	0	114.5	G22 L23 L24	G22-A26 WeakPolarHBondContact O-CB 3.37Å; G22-A26 PolarHBondContact O-N 2.85Å; L23-A26 PolarHBondContact O-N 3.46Å; L24-A26 VanDerWaalsContact C-N 3.32Å; L24-A26 PolarHBondContact O-N 2.88Å
27	G	45.5	Very low	51.8	Low	50 Å²	50	97.6 Å²	97.6	52%	0.515	57%	0.57	S	S	.	*	H	α-helix	trans	-95.6	-35.9	-173	0	0	0	0	0	114.5	L23 L24 G29 G30	L23-G27 WeakPolarHBondContact O-CA 3.37Å; L23-G27 PolarHBondContact O-N 3.22Å; L24-G27 PolarHBondContact O-N 3.2Å; G27-G29 VanDerWaalsContact C-N 3.31Å; G27-G29 PolarHBondContact O-N 3.06Å; G27-G30 PolarHBondContact O-N 3.24Å
28	L	52.8	Low	51	Low	104 Å²	104	100.3 Å²	100.3	55%	0.545	58%	0.581	S	S	.	*	H	α-helix	trans	-70.5	-27.3	178.9	-69.7	175.9	0	0	0	112.8	L24 G30	L24-L28 HydrophobicContact CD1-CD1 4.08Å; L24-L28 HydrophobicContact CD1-CG 4.49Å; L24-L28 HydrophobicContact CD2-CD1 4.37Å; L24-L28 HydrophobicContact CG-CD1 3.8Å; L24-L28 HydrophobicContact CG-CG 4.4Å; L24-L28 WeakPolarHBondContact O-CB 3.45Å; L24-L28 WeakPolarHBondContact O-CG 3.49Å; L24-L28 PolarHBondContact O-N 2.96Å; L28-G30 PolarHBondContact O-N 3.44Å
29	G	45.6	Very low	50	Low	57 Å²	57	103.4 Å²	103.4	59%	0.588	60%	0.599	S	S	*	*	T	Hydrogen-bonded Turn	trans	-80.2	11.8	174.6	0	0	0	0	0	115.2	G27	G27-G29 VanDerWaalsContact C-N 3.31Å; G27-G29 PolarHBondContact O-N 3.06Å
30	G	43.2	Very low	49.2	Very low	59 Å²	59	108.3 Å²	108.3	61%	0.608	61%	0.613	S	S	*	*	T	Hydrogen-bonded Turn	trans	-104.2	9	-178.4	0	0	0	0	0	115	G27 L28	G27-G30 PolarHBondContact O-N 3.24Å; L28-G30 PolarHBondContact O-N 3.44Å
31	H	46.8	Very low	48.2	Very low	170 Å²	170	110.3 Å²	110.3	79%	0.787	62%	0.621	S	S	*	*	S	Bend	trans	-128.5	2.8	-166.7	-139.3	-76.1	0	0	0	115.6
32	D	48.6	Very low	47.2	Very low	132 Å²	132	115.8 Å²	115.8	71%	0.706	64%	0.642	S	S	*	*	S	Bend	trans	-106.1	-6	-178.8	-69.1	-30.8	0	0	0	114	L34	D32-L34 VanDerWaalsContact C-N 3.26Å; D32-L34 PolarHBondContact O-N 3.04Å
33	D	46.8	Very low	46.5	Very low	154 Å²	154	122.8 Å²	122.8	82%	0.824	66%	0.664	S	S	*	*	S	Bend	trans	-85.7	27.4	-178.8	-73.3	-38.5	0	0	0	113.8
34	L	42.7	Very low	45.6	Very low	156 Å²	156	119.6 Å²	119.6	82%	0.817	66%	0.664	S	S	*	*			trans	-144.1	55.9	-178.1	-157.5	83.7	0	0	0	114.1	D32	D32-L34 VanDerWaalsContact C-N 3.26Å; D32-L34 PolarHBondContact O-N 3.04Å
35	H	47.1	Very low	45	Very low	170 Å²	170	124.6 Å²	124.6	79%	0.787	69%	0.685	S	S	*	*	S	Bend	trans	-138.2	105.6	161	-96.8	-66.6	0	0	0	113.5
36	D	43.7	Very low	44.2	Very low	120 Å²	120	128.1 Å²	128.1	64%	0.642	71%	0.711	S	S	*	*			trans	50.3	92	149.1	-58.9	-50	0	0	0	119.8	L38	D36-L38 HydrophobicContact CB-CB 4.4Å; D36-L38 HydrophobicContact CB-CD1 4.15Å; D36-L38 HydrophobicContact CB-CG 4.23Å; D36-L38 PolarHBondContact O-N 3.48Å
37	D	42	Very low	43.9	Very low	181 Å²	181	134.6 Å²	134.6	97%	0.968	73%	0.733	S	S	*	*			trans	-56.7	85.3	136.1	-78.5	-53.8	0	0	0	110
38	L	43.6	Very low	43.4	Very low	130 Å²	130	143.6 Å²	143.6	68%	0.681	75%	0.751	S	S	*	*			trans	-117.5	93.3	166.4	-87.4	171.5	0	0	0	111.3	D36 E40	D36-L38 HydrophobicContact CB-CB 4.4Å; D36-L38 HydrophobicContact CB-CD1 4.15Å; D36-L38 HydrophobicContact CB-CG 4.23Å; D36-L38 PolarHBondContact O-N 3.48Å; L38-E40 PolarHBondContact O-N 2.97Å; L38-E40 VanDerWaalsContact O-N 3.12Å
39	Q	38.7	Very low	43.1	Very low	162 Å²	162	146.8 Å²	146.8	76%	0.757	76%	0.763	S	S	*	*			trans	-65.9	97.1	165.5	177.1	-177.5	-31	0	0	109.9	D41	Q39-D41 PolarHBondContact NE2-OD2 3.45Å; Q39-D41 PolarHBondContact O-N 3.43Å
40	E	42.3	Very low	42.8	Very low	155 Å²	155	148.9 Å²	148.9	72%	0.724	77%	0.769	S	S	*	*			trans	-89.8	95.1	167.7	-72.5	-148.7	148.4	0	0	111.7	L38 F42	L38-E40 PolarHBondContact O-N 2.97Å; L38-E40 VanDerWaalsContact O-N 3.12Å; E40-F42 HydrophobicContact CB-CD2 4.47Å; E40-F42 PolarHBondContact O-N 3.17Å
41	D	40.7	Very low	43.2	Very low	123 Å²	123	155 Å²	155	66%	0.658	78%	0.781	S	S	*	*			trans	-71.4	97	166.1	-77.8	-57.5	0	0	0	110.9	Q39	Q39-D41 PolarHBondContact NE2-OD2 3.45Å; Q39-D41 PolarHBondContact O-N 3.43Å
42	F	40.9	Very low	42.9	Very low	174 Å²	174	154.9 Å²	154.9	76%	0.763	78%	0.781	S	S	*	*			trans	-106.6	94.3	171.1	-101.9	-77.7	0	0	0	113.4	E40	E40-F42 HydrophobicContact CB-CD2 4.47Å; E40-F42 PolarHBondContact O-N 3.17Å
43	H	41	Very low	42.9	Very low	188 Å²	188	155.1 Å²	155.1	87%	0.87	78%	0.782	S	S	*	*			trans	-75.1	117.7	159.1	-73.4	-47	0	0	0	110.1
44	G	40.3	Very low	42.6	Very low	70 Å²	70	156.2 Å²	156.2	72%	0.722	78%	0.78	S	S	*	*			trans	-147.5	93.7	-175.9	0	0	0	0	0	114
45	H	44.3	Very low	42.8	Very low	185 Å²	185	155.4 Å²	155.4	86%	0.856	77%	0.772	S	S	*	*			trans	-3	137.4	171.2	-62.3	-69.6	0	0	0	122.7
46	S	37.3	Very low	42.9	Very low	105 Å²	105	155.3 Å²	155.3	73%	0.734	77%	0.771	S	S	*	*			trans	-58.2	139.7	165.9	55.2	0	0	0	0	115.2
47	H	47.2	Very low	42.9	Very low	182 Å²	182	153.4 Å²	153.4	84%	0.843	78%	0.78	S	S	*	*			trans	-141.4	139.4	140.6	-91.7	-78	0	0	0	110.9
48	R	35.8	Very low	43.2	Very low	239 Å²	239	153.7 Å²	153.7	90%	0.902	78%	0.775	S	S	*	*			trans	-118.3	116.1	-176.2	177.5	-175	-177.1	-177.6	1.6	108
49	H	46.9	Very low	43.4	Very low	170 Å²	170	153.2 Å²	153.2	79%	0.787	78%	0.783	S	S	*	*			trans	-128.8	120.5	168.3	-85.2	-79.5	0	0	0	110.5
50	S	39.4	Very low	44.1	Very low	102 Å²	102	153.3 Å²	153.3	71%	0.713	78%	0.783	S	S	*	*			trans	-89.3	137.5	165.8	48	0	0	0	0	109.4
51	H	51.9	Low	44.4	Very low	186 Å²	186	150.9 Å²	150.9	86%	0.861	79%	0.789	S	S	*	*			trans	-139.2	121.2	154.5	-106.1	-80.7	0	0	0	108.3
52	E	41	Very low	44.9	Very low	168 Å²	168	152.6 Å²	152.6	79%	0.785	79%	0.793	S	S	*	*			trans	-94.5	173.4	168.1	-65.9	-178.4	119	0	0	109.8
53	D	47.4	Very low	45.1	Very low	137 Å²	137	148.2 Å²	148.2	73%	0.733	80%	0.797	S	S	*	*			trans	95.8	144.4	157.3	-53.5	-33	0	0	0	121.6
54	F	41.7	Very low	45.5	Very low	178 Å²	178	147.5 Å²	147.5	78%	0.781	79%	0.794	S	S	*	*			trans	89	73.9	164.2	-66.1	-76.7	0	0	0	121.8
55	H	45.4	Very low	45.5	Very low	138 Å²	138	147 Å²	147	64%	0.639	79%	0.789	S	S	*	*				52.4	117.8	112.2	-69.6	-73	0	0	0	122.9
56	H	50.1	Low	45.7	Very low	169 Å²	169	146.5 Å²	146.5	78%	0.782	79%	0.786	S	S	*	*			trans	62.4	123.2	136.9	-58	-52.2	0	0	0	122.6
57	G	43.5	Very low	45.9	Very low	80 Å²	80	148 Å²	148	83%	0.825	79%	0.791	S	S	*	*			trans	-164.8	87.6	157.6	0	0	0	0	0	112.3
58	H	47.8	Very low	46	Very low	187 Å²	187	147.9 Å²	147.9	87%	0.866	79%	0.791	S	S	*	*			trans	-87.2	136.1	167.2	-78.8	-61.7	0	0	0	110.3
59	S	48.2	Very low	46.4	Very low	119 Å²	119	144.6 Å²	144.6	83%	0.832	79%	0.786	S	S	*	*			trans	-145	136.1	156.4	54.3	0	0	0	0	110.2
60	H	52.9	Low	46.3	Very low	165 Å²	165	140.9 Å²	140.9	76%	0.764	78%	0.779	S	S	*	*			trans	-90.7	146.9	177.7	-74.5	-103.9	0	0	0	110.4
61	A	48.8	Very low	46.7	Very low	104 Å²	104	143.2 Å²	143.2	86%	0.86	78%	0.782	S	S	*	*			trans	-128.7	109.8	159.6	0	0	0	0	0	109.1
62	H	51.2	Low	46.3	Very low	159 Å²	159	146.2 Å²	146.2	74%	0.736	79%	0.786	S	S	*	*			trans	-86.8	127.3	167.9	-79.8	-93.6	0	0	0	109.3
63	G	44.2	Very low	46.9	Very low	82 Å²	82	146.5 Å²	146.5	85%	0.845	79%	0.787	S	S	*	*			trans	-113.2	112.6	166.8	0	0	0	0	0	110.2
64	H	50.2	Low	46.5	Very low	173 Å²	173	143.3 Å²	143.3	80%	0.801	79%	0.786	S	S	*	*			trans	-94.2	150.3	175	-86.7	-82	0	0	0	111.6
65	G	40.7	Very low	46.9	Very low	60 Å²	60	143 Å²	143	62%	0.619	79%	0.786	S	S	*	*			trans	75.6	143.4	159.7	0	0	0	0	0	114.7
66	H	48.4	Very low	46.9	Very low	173 Å²	173	142.9 Å²	142.9	80%	0.801	80%	0.795	S	S	*	*			cis	-155.7	152.1	24.7	-76.8	-87.9	0	0	0	110.4
67	T	41.9	Very low	47.3	Very low	137 Å²	137	141.4 Å²	141.4	84%	0.84	79%	0.789	S	S	*	*			trans	-70.5	132.5	162.6	45.8	0	0	0	0	109.9
68	H	48.4	Very low	47.4	Very low	180 Å²	180	145.2 Å²	145.2	83%	0.833	79%	0.79	S	S	*	*			trans	-121	127.8	163.5	-99.1	-86.6	0	0	0	110.1
69	E	44.4	Very low	48	Very low	170 Å²	170	144.1 Å²	144.1	79%	0.794	79%	0.785	S	S	*	*			trans	-81.7	163.8	173.1	-58.8	-178.6	131.1	0	0	111.2
70	S	45.8	Very low	47.9	Very low	92 Å²	92	144.7 Å²	144.7	64%	0.643	78%	0.778	S	S	*	*			trans	43.6	113.3	146.1	59.4	0	0	0	0	120.4
71	I	45.8	Very low	48	Very low	151 Å²	151	145 Å²	145	77%	0.774	78%	0.78	S	S	*	*			trans	-145.2	111.3	137.2	-88	131.4	0	0	0	107.4
72	W	43.7	Very low	47.8	Very low	249 Å²	249	143.7 Å²	143.7	94%	0.943	78%	0.777	S	S	*	*			trans	-176.9	64.5	144.2	-83.8	122.7	0	0	0	107.2
73	H	54	Low	47.7	Very low	174 Å²	174	145.4 Å²	145.4	81%	0.806	79%	0.785	S	S	*	*			trans	-122.3	129.3	175.3	-91.7	-64.6	0	0	0	110.3
74	G	39.7	Very low	47.7	Very low	69 Å²	69	146.6 Å²	146.6	71%	0.711	78%	0.78	S	S	*	*			trans	52.5	100.5	144.3	0	0	0	0	0	119.8
75	H	49	Very low	47.8	Very low	173 Å²	173	146.2 Å²	146.2	80%	0.801	78%	0.778	S	S	*	*			trans	-119.5	104.3	144.3	-76.7	-54.4	0	0	0	110.2
76	T	47.2	Very low	48.1	Very low	134 Å²	134	151 Å²	151	82%	0.822	79%	0.785	S	S	*	*			trans	-72.6	123.8	159.1	44.4	0	0	0	0	108.6
77	H	57.9	Low	48.1	Very low	139 Å²	139	149.3 Å²	149.3	64%	0.644	78%	0.782	S	S	*	*			trans	-108.1	95.7	168.7	-80.5	-90.8	0	0	0	109.4	H79	H77-H79 AromaticContact ND1-CD2 3.97Å; H77-H79 AromaticContact ND1-NE2 3.44Å; H77-H79 PolarHBondContact ND1-NE2 2.81Å
78	D	44.2	Very low	48.2	Very low	159 Å²	159	148.2 Å²	148.2	85%	0.85	77%	0.77	S	S	*	*			trans	-72.3	122.7	153.1	-79.7	-48.7	0	0	0	107.6
79	H	60.9	Low	48.3	Very low	165 Å²	165	149.1 Å²	149.1	76%	0.764	77%	0.774	S	S	*	*			trans	-124.9	124.1	166.2	-86.1	-60.3	0	0	0	109.8	H77	H77-H79 AromaticContact ND1-CD2 3.97Å; H77-H79 AromaticContact ND1-NE2 3.44Å; H77-H79 PolarHBondContact ND1-NE2 2.81Å
80	D	45.7	Very low	48.7	Very low	130 Å²	130	149.1 Å²	149.1	70%	0.695	77%	0.774	S	S	*	*			trans	-90.4	150.9	-164.1	-134.2	-14.1	0	0	0	113
81	H	55.9	Low	48.6	Very low	172 Å²	172	148 Å²	148	80%	0.796	78%	0.776	S	S	*	*			trans	63.9	126.3	152.3	-60.9	-11	0	0	0	121
82	G	44	Very low	48.7	Very low	77 Å²	77	149.7 Å²	149.7	79%	0.794	78%	0.781	S	S	*	*			trans	177.3	61.3	166.7	0	0	0	0	0	115.1
83	H	49.9	Very low	48.6	Very low	195 Å²	195	142.8 Å²	142.8	90%	0.903	77%	0.771	S	S	*	*			trans	-108.6	122.9	174.6	-77.1	-62	0	0	0	113
84	S	43.9	Very low	48.7	Very low	107 Å²	107	143.5 Å²	143.5	75%	0.748	77%	0.774	S	S	*	*			trans	-167.2	126.1	148.4	23.6	0	0	0	0	109.6
85	H	53.3	Low	48.7	Very low	165 Å²	165	143.4 Å²	143.4	76%	0.764	77%	0.773	S	S	*	*				55.1	128.3	102.7	-69.5	-93.1	0	0	0	113.1
86	E	45.3	Very low	48.4	Very low	161 Å²	161	146 Å²	146	75%	0.752	78%	0.778	S	S	*	*			cis	-154.6	-173.5	13.8	-116.9	138.7	-152.2	0	0	107.8
87	D	49.4	Very low	48.1	Very low	137 Å²	137	144.9 Å²	144.9	73%	0.733	78%	0.775	S	S	*	*			cis	-151.7	-178	21.7	-163.5	10.6	0	0	0	112.3
88	L	43.2	Very low	47.7	Very low	113 Å²	113	147.5 Å²	147.5	59%	0.592	79%	0.787	S	S	*	*			trans	-62.9	153.2	176.4	-83.2	49.5	0	0	0	117.3
89	H	51.3	Low	47.5	Very low	199 Å²	199	148.3 Å²	148.3	92%	0.921	79%	0.786	S	S	*	*				-149.1	123.3	129.7	-88.7	-61.6	0	0	0	111.9
90	H	52.5	Low	46.7	Very low	171 Å²	171	144.8 Å²	144.8	79%	0.792	78%	0.78	S	S	*	*			trans	-115.9	156.9	176	-73.2	-66.9	0	0	0	111.7
91	G	43.8	Very low	46.5	Very low	68 Å²	68	146.5 Å²	146.5	70%	0.701	79%	0.788	S	S	*	*			trans	151.4	87.7	165.9	0	0	0	0	0	112.1
92	H	48.6	Very low	45.8	Very low	186 Å²	186	147.9 Å²	147.9	86%	0.861	79%	0.788	S	S	*	*				83.9	123.3	81.1	-77.6	10.9	0	0	0	115
93	S	40.6	Very low	46.1	Very low	105 Å²	105	153.9 Å²	153.9	73%	0.734	80%	0.795	S	S	*	*			trans	-99.8	137.6	-178.4	53.1	0	0	0	0	112
94	H	55.5	Low	45.7	Very low	188 Å²	188	156 Å²	156	87%	0.87	80%	0.795	S	S	*	*			trans	-144.4	135.2	154	-79.1	-71.8	0	0	0	109.7
95	G	40.6	Very low	45.7	Very low	68 Å²	68	153.9 Å²	153.9	70%	0.701	79%	0.79	S	S	*	*			trans	-103.9	157.2	174.5	0	0	0	0	0	111.7
96	Y	43.2	Very low	45.6	Very low	228 Å²	228	154.8 Å²	154.8	89%	0.894	79%	0.794	S	S	*	*			trans	-141.1	126.9	159.7	-89.3	-78.2	0	0	0	109.8
97	S	41	Very low	45.5	Very low	110 Å²	110	150.5 Å²	150.5	77%	0.769	79%	0.793	S	S	*	*			trans	-81.5	144.4	166.5	49.4	0	0	0	0	110.3
98	H	48	Very low	45.8	Very low	193 Å²	193	151 Å²	151	89%	0.894	79%	0.791	S	S	*	*			trans	-136.6	135.5	160.2	-122.1	-85.3	0	0	0	110.8
99	E	41.5	Very low	45.8	Very low	176 Å²	176	153.6 Å²	153.6	82%	0.822	81%	0.805	S	S	*	*			trans	-80.5	155.5	-171.9	-77	179.3	96.4	0	0	114.3
100	S	42.6	Very low	46.1	Very low	92 Å²	92	151 Å²	151	64%	0.643	79%	0.793	S	S	*	*			trans	23.9	126.4	147	69.9	0	0	0	0	120.3
101	L	41.4	Very low	45.7	Very low	165 Å²	165	152.8 Å²	152.8	86%	0.864	80%	0.802	S	S	*	*				-155.1	142.1	121.6	-114	145.3	0	0	0	112.3
102	Y	43.1	Very low	46.1	Very low	202 Å²	202	156.7 Å²	156.7	79%	0.792	80%	0.801	S	S	*	*			trans	-62	141.1	-177.5	-59.6	-101.1	0	0	0	112.2
103	H	49.5	Very low	45.7	Very low	202 Å²	202	153.7 Å²	153.7	94%	0.935	80%	0.801	S	S	*	*			trans	-155.2	147.4	130.8	-104.5	-70.7	0	0	0	111.4
104	R	41.5	Very low	46.5	Very low	240 Å²	240	156.8 Å²	156.8	91%	0.906	80%	0.804	S	S	*	*			trans	-122.2	127.6	-168	171.7	179.8	179.3	157.9	0	110
105	G	43.6	Very low	45.7	Very low	62 Å²	62	151.8 Å²	151.8	64%	0.639	80%	0.803	S	S	*	*			trans	84.1	118.1	164.3	0	0	0	0	0	115.4
106	H	50.7	Low	45.8	Very low	184 Å²	184	151.9 Å²	151.9	85%	0.852	80%	0.804	S	S	*	*				-173.7	134	106.3	-95.3	-73.8	0	0	0	108.2
107	G	42.8	Very low	45.8	Very low	72 Å²	72	152.8 Å²	152.8	74%	0.742	81%	0.808	S	S	*	*			trans	-85.3	136	176	0	0	0	0	0	110.7
108	H	55.9	Low	45.6	Very low	148 Å²	148	150.8 Å²	150.8	69%	0.685	81%	0.805	S	S	*	*			trans	-142.5	116.4	164.6	-81.1	-72.2	0	0	0	108.8
109	D	44.8	Very low	45.5	Very low	167 Å²	167	151.1 Å²	151.1	89%	0.893	81%	0.807	S	S	*	*			trans	-70.3	126	170.6	-55.9	-62.4	0	0	0	109.1
110	H	56.4	Low	45.2	Very low	145 Å²	145	148.8 Å²	148.8	67%	0.671	81%	0.81	S	S	*	*			trans	-127.7	91.7	175	-79.4	-63.4	0	0	0	110.2	H112	H110-H112 PolarHBondContact O-N 2.82Å
111	E	43.4	Very low	44.9	Very low	207 Å²	207	147.7 Å²	147.7	97%	0.967	81%	0.814	S	S	*	*			trans	-71.2	107.7	166.1	-118.4	177.1	105	0	0	109.3
112	H	52.9	Low	44.8	Very low	150 Å²	150	144 Å²	144	69%	0.694	81%	0.806	S	S	*	*			trans	-91.2	110.1	175.1	-79.9	-78.5	0	0	0	110.7	H110 H114	H110-H112 PolarHBondContact O-N 2.82Å; H112-H114 PolarHBondContact O-N 3.45Å
113	S	41.1	Very low	44.7	Very low	123 Å²	123	139.9 Å²	139.9	86%	0.86	80%	0.804	S	S	*	*			trans	-71	116.7	172.2	-168.9	0	0	0	0	110.6
114	H	56.8	Low	44.3	Very low	171 Å²	171	133.8 Å²	133.8	79%	0.792	80%	0.797	S	S	*	*			trans	-108.8	112.7	166.8	-80.8	-79.6	0	0	0	109.6	H112 G116	H112-H114 PolarHBondContact O-N 3.45Å; H114-G116 PolarHBondContact O-N 3.46Å
115	G	39.3	Very low	44.5	Very low	82 Å²	82	129.4 Å²	129.4	85%	0.845	79%	0.79	S	S	*	*			trans	-69.7	117.9	171.4	0	0	0	0	0	110.9
116	G	42	Very low	44.9	Very low	71 Å²	71	134.8 Å²	134.8	73%	0.732	80%	0.795	S	S	*	*			trans	-119.4	126.4	169.1	0	0	0	0	0	109.8	H114 G118	H114-G116 PolarHBondContact O-N 3.46Å; G116-G118 PolarHBondContact O-N 2.89Å
117	Y	42.7	Very low	45.1	Very low	246 Å²	246	131.3 Å²	131.3	97%	0.965	78%	0.779	S	S	*	*			trans	-70.2	98.5	171.5	-69.8	-96	0	0	0	108.7
118	G	38.4	Very low	46.1	Very low	69 Å²	69	135.2 Å²	135.2	71%	0.711	78%	0.783	S	S	*	*			trans	-98.1	117.4	176.7	0	0	0	0	0	111.5	G116 S120	G116-G118 PolarHBondContact O-N 2.89Å; G118-S120 PolarHBondContact O-N 2.91Å
119	E	43.9	Very low	47.1	Very low	200 Å²	200	130 Å²	130	94%	0.935	76%	0.76	S	S	*	*			trans	-62	131.2	164.5	-73.9	-177.7	102.9	0	0	109.7	G121	E119-G121 PolarHBondContact O-N 3.38Å
120	S	35.8	Very low	49	Very low	126 Å²	126	126.2 Å²	126.2	88%	0.881	74%	0.74	S	S	*	*			trans	-79	69.3	-172.7	-166	0	0	0	0	112.1	G118 A122	G118-S120 PolarHBondContact O-N 2.91Å; S120-A122 PolarHBondContact O-N 2.68Å
121	G	37.8	Very low	50.5	Low	70 Å²	70	122.5 Å²	122.5	72%	0.722	74%	0.735	S	S	*	*			trans	-77.7	96	166.4	0	0	0	0	0	110.2	E119	E119-G121 PolarHBondContact O-N 3.38Å
122	A	37.8	Very low	52.8	Low	86 Å²	86	118.1 Å²	118.1	71%	0.711	72%	0.722	S	S	*	*			trans	-63.6	132.7	179.1	0	0	0	0	0	111.3	S120 G124	S120-A122 PolarHBondContact O-N 2.68Å; A122-G124 PolarHBondContact O-N 3.48Å
123	P	42.3	Very low	54.6	Low	116 Å²	116	113 Å²	113	75%	0.753	70%	0.701	S	S	*	*			trans	-66.2	127.2	173.2	28.1	-33	0	0	0	108.8	I125	P123-I125 PolarHBondContact O-N 2.75Å
124	G	41.2	Very low	57.1	Low	75 Å²	75	108 Å²	108	77%	0.773	67%	0.665	S	S	*	*			trans	-59.8	108.2	-179.6	0	0	0	0	0	111	A122 K126	A122-G124 PolarHBondContact O-N 3.48Å; G124-K126 PolarHBondContact O-N 2.89Å
125	I	44.7	Very low	58.8	Low	148 Å²	148	104 Å²	104	76%	0.759	64%	0.642	S	S	*	*			trans	-61.5	107.8	170.2	-61.4	176.7	0	0	0	106.6	P123 Q127	P123-I125 PolarHBondContact O-N 2.75Å; I125-Q127 HydrophobicContact CG2-CG 4.12Å; I125-Q127 PolarHBondContact O-N 3.18Å
126	K	52	Low	61.5	Low	174 Å²	174	102.9 Å²	102.9	76%	0.757	63%	0.625	S	S	*	*			trans	-61.6	96	162.7	-70.1	-171.6	176.5	-171.3	0	106.5	G124 D128	G124-K126 PolarHBondContact O-N 2.89Å; K126-D128 VanDerWaalsContact C-N 3.28Å; K126-D128 PolarHBondContact O-N 3.2Å
127	Q	54.8	Low	64	Low	111 Å²	111	104.2 Å²	104.2	52%	0.519	61%	0.609	S	S	.	*			trans	-72.8	92	171	-67	-171.5	-55.2	0	0	106.5	I125 L129	I125-Q127 HydrophobicContact CG2-CG 4.12Å; I125-Q127 PolarHBondContact O-N 3.18Å; Q127-L129 PolarHBondContact O-N 3.09Å
128	D	64.8	Low	66.5	Low	154 Å²	154	92.5 Å²	92.5	82%	0.824	56%	0.563	S	S	*	*			trans	-55.9	109	168.5	-73.8	-22.6	0	0	0	107.7	K126	K126-D128 VanDerWaalsContact C-N 3.28Å; K126-D128 PolarHBondContact O-N 3.2Å
129	L	75.4	Confident	69.2	Low	39 Å²	39	91.9 Å²	91.9	20%	0.204	54%	0.543	C	S	.	.			trans	-68.1	133.1	172.8	-66.5	164.9	0	0	0	107.1	Q127 T133 L134 Y137 F341 R345	Q127-L129 PolarHBondContact O-N 3.09Å; L129-T133 HydrophobicContact CD2-CG2 3.92Å; L129-L134 HydrophobicContact CB-CB 3.96Å; L129-L134 HydrophobicContact CD1-CD1 4.05Å; L129-Y137 HydrophobicContact CD1-CD2 4.12Å; L129-Y137 HydrophobicContact CD2-CD2 3.95Å; L129-Y137 HydrophobicContact CD2-CE2 3.74Å; L129-F341 HydrophobicContact CD1-CD1 4.49Å; L129-R345 HydrophobicContact CD1-CB 4.16Å; L129-R345 HydrophobicContact CD2-CB 4.34Å
130	D	86.3	Confident	71.7	Confident	87 Å²	87	84.3 Å²	84.3	47%	0.465	52%	0.519	S	S	.	.			trans	-59.6	153.2	167.5	72.5	-90.7	0	0	0	109.5	V132 T133 L134	D130-V132 PolarHBondContact O-N 3.25Å; D130-V132 VanDerWaalsContact O-N 3.11Å; D130-V132 WeakPolarHBondContact OD2-CA 3.26Å; D130-V132 WeakPolarHBondContact OD2-CB 3.42Å; D130-V132 PolarHBondContact OD2-N 3.34Å; D130-T133 PolarHBondContact O-N 2.99Å; D130-T133 VanDerWaalsContact O-N 3.13Å; D130-T133 WeakPolarHBondContact OD1-CB 3.11Å; D130-T133 PolarHBondContact OD1-OG1 3.23Å; D130-T133 PolarHBondContact OD2-N 3.48Å; D130-T133 PolarHBondContact OD2-OG1 2.79Å; D130-L134 WeakPolarHBondContact O-CB 3.41Å; D130-L134 PolarHBondContact O-N 3.21Å
131	A	87.7	Confident	74.6	Confident	68 Å²	68	78.8 Å²	78.8	56%	0.562	48%	0.481	S	S	*	.	H	α-helix	trans	-57.5	-32.9	-172.4	0	0	0	0	0	113.3	W135	A131-W135 WeakPolarHBondContact O-CB 3.15Å; A131-W135 PolarHBondContact O-N 3.21Å; A131-W135 VanDerWaalsContact O-N 3.12Å
132	V	90.6	Very high	77.3	Confident	115 Å²	115	75.4 Å²	75.4	70%	0.697	45%	0.446	S	S	*	.	H	α-helix	trans	-72.7	-45.8	179.7	-177.6	0	0	0	0	110.2	D130 W135 A136	D130-V132 PolarHBondContact O-N 3.25Å; D130-V132 VanDerWaalsContact O-N 3.11Å; D130-V132 WeakPolarHBondContact OD2-CA 3.26Å; D130-V132 WeakPolarHBondContact OD2-CB 3.42Å; D130-V132 PolarHBondContact OD2-N 3.34Å; V132-W135 PolarHBondContact O-N 2.83Å; V132-A136 VanDerWaalsContact O-CB 3.27Å; V132-A136 WeakPolarHBondContact O-CB 3.46Å; V132-A136 PolarHBondContact O-N 2.84Å
133	T	92.2	Very high	80	Confident	41 Å²	41	75.2 Å²	75.2	25%	0.252	44%	0.436	S	S	.	.	H	α-helix	trans	-64.9	-38.9	176.4	-57.7	0	0	0	0	111.9	L129 D130 A136 Y137	L129-T133 HydrophobicContact CD2-CG2 3.92Å; D130-T133 PolarHBondContact O-N 2.99Å; D130-T133 VanDerWaalsContact O-N 3.13Å; D130-T133 WeakPolarHBondContact OD1-CB 3.11Å; D130-T133 PolarHBondContact OD1-OG1 3.23Å; D130-T133 PolarHBondContact OD2-N 3.48Å; D130-T133 PolarHBondContact OD2-OG1 2.79Å; T133-A136 PolarHBondContact O-N 3.45Å; T133-Y137 HydrophobicContact CG2-CD1 4.23Å; T133-Y137 HydrophobicContact CG2-CD2 3.88Å; T133-Y137 HydrophobicContact CG2-CE1 3.88Å; T133-Y137 HydrophobicContact CG2-CE2 3.49Å; T133-Y137 VanDerWaalsContact CG2-CE2 3.49Å; T133-Y137 HydrophobicContact CG2-CG 4.24Å; T133-Y137 VanDerWaalsContact CG2-CZ 3.5Å; T133-Y137 WeakPolarHBondContact O-CB 3.5Å; T133-Y137 PolarHBondContact O-N 3.09Å
134	L	91.8	Very high	82.5	Confident	19 Å²	19	73.8 Å²	73.8	10%	0.099	42%	0.422	C	S	.	.	H	α-helix	trans	-57.2	-53.5	174.7	174.4	63.6	0	0	0	111.3	L129 D130 Y137 A138 F341 R342 L399	L129-L134 HydrophobicContact CB-CB 3.96Å; L129-L134 HydrophobicContact CD1-CD1 4.05Å; D130-L134 WeakPolarHBondContact O-CB 3.41Å; D130-L134 PolarHBondContact O-N 3.21Å; L134-Y137 PolarHBondContact O-N 3.46Å; L134-A138 WeakPolarHBondContact O-CB 3.44Å; L134-A138 PolarHBondContact O-N 3.27Å; L134-F341 HydrophobicContact CD1-CB 3.87Å; L134-F341 WeakPolarHBondContact CD1-O 3.46Å; L134-R342 HydrophobicContact CD2-CG 4.4Å; L134-L399 HydrophobicContact CD1-CD2 4.21Å; L134-L399 HydrophobicContact CD2-CD2 4.08Å; L134-L399 HydrophobicContact CG-CD2 3.86Å
135	W	94.1	Very high	84.9	Confident	86 Å²	86	70.2 Å²	70.2	33%	0.326	39%	0.385	S	S	.	.	H	α-helix	trans	-63.5	-41.2	178.7	-83.7	68.9	0	0	0	111.9	A131 V132 L139 L399 L400	A131-W135 WeakPolarHBondContact O-CB 3.15Å; A131-W135 PolarHBondContact O-N 3.21Å; A131-W135 VanDerWaalsContact O-N 3.12Å; V132-W135 PolarHBondContact O-N 2.83Å; W135-L139 HydrophobicContact CE3-CD1 4Å; W135-L139 VanDerWaalsContact O-CB 3.27Å; W135-L139 WeakPolarHBondContact O-CB 3.42Å; W135-L139 WeakPolarHBondContact O-CG 3.39Å; W135-L139 PolarHBondContact O-N 3.45Å; W135-L399 HydrophobicContact CB-CD1 4.46Å; W135-L399 HydrophobicContact CD2-CB 4.24Å; W135-L399 HydrophobicContact CD2-CD1 3.68Å; W135-L399 HydrophobicContact CE3-CD1 3.89Å; W135-L399 HydrophobicContact CG-CD1 3.93Å; W135-L399 HydrophobicContact CH2-CB 4.19Å; W135-L399 HydrophobicContact CZ2-CB 3.64Å; W135-L399 HydrophobicContact CZ2-CD1 4.48Å; W135-L399 HydrophobicContact CZ3-CD1 4.37Å; W135-L400 HydrophobicContact CH2-CD2 3.87Å; W135-L400 HydrophobicContact CH2-CG 3.84Å; W135-L400 HydrophobicContact CZ2-CD2 3.89Å; W135-L400 HydrophobicContact CZ2-CG 4.03Å
136	A	95.1	Very high	87.1	Confident	59 Å²	59	63.6 Å²	63.6	49%	0.488	35%	0.352	S	S	.	.	H	α-helix	trans	-63.9	-40.6	178.2	0	0	0	0	0	112.7	V132 T133 G140	V132-A136 VanDerWaalsContact O-CB 3.27Å; V132-A136 WeakPolarHBondContact O-CB 3.46Å; V132-A136 PolarHBondContact O-N 2.84Å; T133-A136 PolarHBondContact O-N 3.45Å; A136-G140 WeakPolarHBondContact O-CA 3.29Å; A136-G140 PolarHBondContact O-N 3.01Å
137	Y	94.8	Very high	88.9	Confident	99 Å²	99	57 Å²	57	39%	0.388	33%	0.329	S	S	.	.	H	α-helix	trans	-70.8	-47	177.5	-72.9	-7	0	0	0	112.2	L129 T133 L134 G140 A141 F341 R345	L129-Y137 HydrophobicContact CD1-CD2 4.12Å; L129-Y137 HydrophobicContact CD2-CD2 3.95Å; L129-Y137 HydrophobicContact CD2-CE2 3.74Å; T133-Y137 HydrophobicContact CG2-CD1 4.23Å; T133-Y137 HydrophobicContact CG2-CD2 3.88Å; T133-Y137 HydrophobicContact CG2-CE1 3.88Å; T133-Y137 HydrophobicContact CG2-CE2 3.49Å; T133-Y137 VanDerWaalsContact CG2-CE2 3.49Å; T133-Y137 HydrophobicContact CG2-CG 4.24Å; T133-Y137 VanDerWaalsContact CG2-CZ 3.5Å; T133-Y137 WeakPolarHBondContact O-CB 3.5Å; T133-Y137 PolarHBondContact O-N 3.09Å; L134-Y137 PolarHBondContact O-N 3.46Å; Y137-G140 PolarHBondContact O-N 2.91Å; Y137-A141 VanDerWaalsContact O-CB 3.28Å; Y137-A141 WeakPolarHBondContact O-CB 3.07Å; Y137-A141 PolarHBondContact O-N 2.96Å; Y137-F341 HydrophobicContact CD2-CE1 4.33Å; Y137-F341 HydrophobicContact CG-CE1 4.4Å; Y137-R345 HydrophobicContact CD2-CG 4.28Å; Y137-R345 HydrophobicContact CE2-CG 4.14Å
138	A	94.3	Very high	90.3	Very high	0 Å²	0	52.7 Å²	52.7	0%	0	31%	0.313	C	S	.	.	H	α-helix	trans	-65.1	-46.6	180	0	0	0	0	0	112.1	L134 A141 T142 F341 T395 L399	L134-A138 WeakPolarHBondContact O-CB 3.44Å; L134-A138 PolarHBondContact O-N 3.27Å; A138-A141 PolarHBondContact O-N 3.21Å; A138-T142 WeakPolarHBondContact O-CB 3.4Å; A138-T142 PolarHBondContact O-N 3.49Å; A138-T142 PolarHBondContact O-OG1 3.2Å; A138-F341 HydrophobicContact CB-CB 4.11Å; A138-F341 HydrophobicContact CB-CD2 3.97Å; A138-F341 HydrophobicContact CB-CG 4.2Å; A138-T395 HydrophobicContact CB-CG2 3.82Å; A138-L399 HydrophobicContact CB-CD1 3.92Å; A138-L399 HydrophobicContact CB-CD2 4.17Å; A138-L399 HydrophobicContact CB-CG 4.43Å
139	L	96.2	Very high	91.1	Very high	56 Å²	56	45.4 Å²	45.4	29%	0.293	27%	0.274	S	S	.	.	H	α-helix	trans	-67.2	-37.6	175	-67.1	175.6	0	0	0	112.1	W135 T142 V143 L392 T395	W135-L139 HydrophobicContact CE3-CD1 4Å; W135-L139 VanDerWaalsContact O-CB 3.27Å; W135-L139 WeakPolarHBondContact O-CB 3.42Å; W135-L139 WeakPolarHBondContact O-CG 3.39Å; W135-L139 PolarHBondContact O-N 3.45Å; L139-T142 PolarHBondContact O-N 2.76Å; L139-V143 WeakPolarHBondContact O-CG2 3.41Å; L139-V143 PolarHBondContact O-N 2.93Å; L139-L392 HydrophobicContact CD2-CD2 4.08Å; L139-T395 HydrophobicContact CD2-CG2 4Å
140	G	96.4	Very high	91.5	Very high	42 Å²	42	47.5 Å²	47.5	43%	0.433	28%	0.282	S	S	.	.	H	α-helix	trans	-63.4	-41.1	175.9	0	0	0	0	0	112.9	A136 Y137 L144	A136-G140 WeakPolarHBondContact O-CA 3.29Å; A136-G140 PolarHBondContact O-N 3.01Å; Y137-G140 PolarHBondContact O-N 2.91Å; G140-L144 WeakPolarHBondContact O-CB 3.38Å; G140-L144 PolarHBondContact O-N 3.37Å
141	A	95.8	Very high	91.4	Very high	9 Å²	9	50.4 Å²	50.4	7%	0.074	29%	0.291	C	S	.	.	H	α-helix	trans	-63.6	-42.9	171.3	0	0	0	0	0	112.3	Y137 A138 L144 I145 I337 F341 T352	Y137-A141 VanDerWaalsContact O-CB 3.28Å; Y137-A141 WeakPolarHBondContact O-CB 3.07Å; Y137-A141 PolarHBondContact O-N 2.96Å; A138-A141 PolarHBondContact O-N 3.21Å; A141-L144 WeakPolarHBondContact O-CB 3.42Å; A141-L144 PolarHBondContact O-N 3.08Å; A141-L144 VanDerWaalsContact O-N 3.12Å; A141-I145 PolarHBondContact O-N 3.05Å; A141-I337 HydrophobicContact CB-CG2 3.89Å; A141-F341 HydrophobicContact CB-CE2 3.53Å; A141-F341 HydrophobicContact CB-CZ 4.08Å; A141-T352 HydrophobicContact CB-CG2 3.64Å; A141-T352 VanDerWaalsContact CB-OG1 3.32Å; A141-T352 WeakPolarHBondContact CB-OG1 3.09Å
142	T	95.4	Very high	91.1	Very high	0 Å²	0	49.4 Å²	49.4	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-61.4	-45.9	177.2	-49.3	0	0	0	0	111.4	A138 L139 L144 I145 S146 A391 L392 T395	A138-T142 WeakPolarHBondContact O-CB 3.4Å; A138-T142 PolarHBondContact O-N 3.49Å; A138-T142 PolarHBondContact O-OG1 3.2Å; L139-T142 PolarHBondContact O-N 2.76Å; T142-L144 VanDerWaalsContact C-N 3.27Å; T142-L144 PolarHBondContact O-N 3.38Å; T142-I145 WeakPolarHBondContact O-CG1 3.4Å; T142-I145 PolarHBondContact O-N 3.41Å; T142-S146 PolarHBondContact O-N 2.98Å; T142-S146 PolarHBondContact O-OG 3.28Å; T142-A391 VanDerWaalsContact CG2-C 3.47Å; T142-A391 HydrophobicContact CG2-CB 3.58Å; T142-L392 HydrophobicContact CG2-CD2 3.83Å; T142-L392 HydrophobicContact CG2-CG 4.15Å; T142-T395 WeakPolarHBondContact OG1-CB 3.43Å; T142-T395 WeakPolarHBondContact OG1-CG2 3.21Å; T142-T395 PolarHBondContact OG1-OG1 3.41Å
143	V	94.8	Very high	90.7	Very high	82 Å²	82	44 Å²	44	50%	0.497	25%	0.245	S	C	.	.	H	α-helix	trans	-64.2	-33.7	174.8	172.5	0	0	0	0	111.5	L139 A147 L392	L139-V143 WeakPolarHBondContact O-CG2 3.41Å; L139-V143 PolarHBondContact O-N 2.93Å; V143-A147 WeakPolarHBondContact O-CB 3.37Å; V143-A147 PolarHBondContact O-N 3.36Å; V143-L392 HydrophobicContact CG2-CD2 4.06Å
144	L	93.5	Very high	90.1	Very high	85 Å²	85	49 Å²	49	45%	0.445	26%	0.263	S	S	.	.	H	α-helix	trans	-66.3	-46.6	177	-179.9	65	0	0	0	112.1	G140 A141 T142 S146 A147 A148	G140-L144 WeakPolarHBondContact O-CB 3.38Å; G140-L144 PolarHBondContact O-N 3.37Å; A141-L144 WeakPolarHBondContact O-CB 3.42Å; A141-L144 PolarHBondContact O-N 3.08Å; A141-L144 VanDerWaalsContact O-N 3.12Å; T142-L144 VanDerWaalsContact C-N 3.27Å; T142-L144 PolarHBondContact O-N 3.38Å; L144-S146 PolarHBondContact O-N 2.81Å; L144-A147 PolarHBondContact O-N 2.91Å; L144-A148 WeakPolarHBondContact O-CB 3.4Å; L144-A148 PolarHBondContact O-N 3Å
145	I	92.4	Very high	89.5	Confident	0 Å²	0	54.8 Å²	54.8	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-62.9	-42.3	179.6	61.4	159.4	0	0	0	111.5	A141 T142 P149 D333 I337 T352 V355 L356	A141-I145 PolarHBondContact O-N 3.05Å; T142-I145 WeakPolarHBondContact O-CG1 3.4Å; T142-I145 PolarHBondContact O-N 3.41Å; I145-P149 WeakPolarHBondContact O-CD 3.44Å; I145-P149 WeakPolarHBondContact O-CG 3.32Å; I145-D333 HydrophobicContact CD1-CB 4.29Å; I145-I337 HydrophobicContact CD1-CD1 3.6Å; I145-I337 HydrophobicContact CG1-CD1 4.15Å; I145-I337 HydrophobicContact CG2-CD1 4.08Å; I145-T352 HydrophobicContact CG2-CG2 4.05Å; I145-V355 HydrophobicContact CB-CG1 4.36Å; I145-V355 HydrophobicContact CD1-CG1 3.61Å; I145-V355 HydrophobicContact CG2-CB 4.49Å; I145-V355 HydrophobicContact CG2-CG1 4.07Å; I145-L356 HydrophobicContact CG2-CB 4.18Å
146	S	91.1	Very high	88.7	Confident	9 Å²	9	51.5 Å²	51.5	6%	0.063	28%	0.282	C	S	.	.	H	α-helix	trans	-79.4	-19.5	-179.5	-45.4	0	0	0	0	113.5	T142 L144 A388	T142-S146 PolarHBondContact O-N 2.98Å; T142-S146 PolarHBondContact O-OG 3.28Å; L144-S146 PolarHBondContact O-N 2.81Å; S146-A388 VanDerWaalsContact CB-CB 3.45Å
147	A	88.8	Confident	87.5	Confident	35 Å²	35	53.7 Å²	53.7	29%	0.289	29%	0.292	S	S	.	.	H	α-helix	trans	-88.3	-29.7	177.3	0	0	0	0	0	113.2	V143 L144 F150 F151	V143-A147 WeakPolarHBondContact O-CB 3.37Å; V143-A147 PolarHBondContact O-N 3.36Å; L144-A147 PolarHBondContact O-N 2.91Å; A147-F150 WeakPolarHBondContact O-CB 3.32Å; A147-F150 PolarHBondContact O-N 2.97Å; A147-F151 WeakPolarHBondContact O-CD2 3.47Å; A147-F151 WeakPolarHBondContact O-CE2 3.35Å
148	A	85.3	Confident	86.2	Confident	22 Å²	22	49.5 Å²	49.5	18%	0.182	28%	0.276	C	S	.	.	H	α-helix	trans	-63.7	-44.8	-176.1	0	0	0	0	0	114.2	L144 F150 F151 L356	L144-A148 WeakPolarHBondContact O-CB 3.4Å; L144-A148 PolarHBondContact O-N 3Å; A148-F150 VanDerWaalsContact C-N 3.26Å; A148-F150 PolarHBondContact O-N 3.19Å; A148-F151 PolarHBondContact O-N 3.45Å; A148-F151 VanDerWaalsContact O-N 3.14Å; A148-L356 HydrophobicContact CB-CD1 3.44Å; A148-L356 VanDerWaalsContact CB-CD1 3.44Å
149	P	80.6	Confident	84.6	Confident	1 Å²	1	56.2 Å²	56.2	1%	0.006	31%	0.308	C	S	.	.	H	α-helix	trans	-57	-37.1	175.3	-25.8	33.4	0	0	0	113.1	I145 F151 V152 L153 V360 E363	I145-P149 WeakPolarHBondContact O-CD 3.44Å; I145-P149 WeakPolarHBondContact O-CG 3.32Å; P149-F151 PolarHBondContact O-N 3.41Å; P149-F151 VanDerWaalsContact O-N 3.16Å; P149-V152 WeakPolarHBondContact O-CA 3.45Å; P149-V152 WeakPolarHBondContact O-CB 3.43Å; P149-V152 PolarHBondContact O-N 3.24Å; P149-L153 WeakPolarHBondContact O-CG 3.15Å; P149-L153 PolarHBondContact O-N 3.19Å; P149-V360 HydrophobicContact CG-CG2 4.08Å; P149-E363 HydrophobicContact CB-CB 3.49Å; P149-E363 VanDerWaalsContact CB-CB 3.49Å; P149-E363 HydrophobicContact CB-CG 3.69Å; P149-E363 HydrophobicContact CG-CB 4.04Å; P149-E363 HydrophobicContact CG-CG 3.79Å
150	F	85.1	Confident	82.6	Confident	82 Å²	82	57 Å²	57	36%	0.36	32%	0.318	S	S	.	.	H	α-helix	trans	-55.4	-35.6	177.7	-169.9	-87.3	0	0	0	113	A147 A148 F154 M381	A147-F150 WeakPolarHBondContact O-CB 3.32Å; A147-F150 PolarHBondContact O-N 2.97Å; A148-F150 VanDerWaalsContact C-N 3.26Å; A148-F150 PolarHBondContact O-N 3.19Å; F150-F154 PolarHBondContact O-N 3.17Å; F150-F154 VanDerWaalsContact O-N 3.14Å; F150-M381 HydrophobicContact CD1-CE 4.21Å; F150-M381 HydrophobicContact CD2-CB 4.31Å; F150-M381 HydrophobicContact CD2-CE 3.92Å; F150-M381 HydrophobicContact CE1-CE 4.04Å; F150-M381 HydrophobicContact CE2-CB 3.97Å; F150-M381 HydrophobicContact CE2-CE 3.74Å; F150-M381 HydrophobicContact CG-CE 4.15Å; F150-M381 HydrophobicContact CZ-CE 3.8Å
151	F	82.9	Confident	80.8	Confident	149 Å²	149	62.7 Å²	62.7	65%	0.654	34%	0.338	S	S	*	.	H	α-helix	trans	-70.5	-36.7	174.8	-65	-81.6	0	0	0	112.5	A147 A148 P149	A147-F151 WeakPolarHBondContact O-CD2 3.47Å; A147-F151 WeakPolarHBondContact O-CE2 3.35Å; A148-F151 PolarHBondContact O-N 3.45Å; A148-F151 VanDerWaalsContact O-N 3.14Å; P149-F151 PolarHBondContact O-N 3.41Å; P149-F151 VanDerWaalsContact O-N 3.16Å
152	V	81.5	Confident	79.4	Confident	47 Å²	47	64.5 Å²	64.5	29%	0.285	35%	0.35	S	S	.	.	H	α-helix	trans	-68	-47.6	176.2	-178.4	0	0	0	0	110.2	P149 F154 L155 V360 V364	P149-V152 WeakPolarHBondContact O-CA 3.45Å; P149-V152 WeakPolarHBondContact O-CB 3.43Å; P149-V152 PolarHBondContact O-N 3.24Å; V152-F154 PolarHBondContact O-N 3.34Å; V152-L155 WeakPolarHBondContact O-CB 3.28Å; V152-L155 PolarHBondContact O-N 2.82Å; V152-V360 HydrophobicContact CB-CG1 4.39Å; V152-V360 HydrophobicContact CG1-CG1 4.25Å; V152-V360 HydrophobicContact CG2-CG1 3.89Å; V152-V364 HydrophobicContact CG1-CG2 4.2Å
153	L	82.2	Confident	78.2	Confident	2 Å²	2	69.6 Å²	69.6	1%	0.01	38%	0.383	C	S	.	.	H	α-helix	trans	-59.8	-31	177.4	-66	178.2	0	0	0	113	P149 L155 I156 V364 F367 K377 M381	P149-L153 WeakPolarHBondContact O-CG 3.15Å; P149-L153 PolarHBondContact O-N 3.19Å; L153-L155 PolarHBondContact O-N 2.7Å; L153-I156 HydrophobicContact CD2-CD1 3.87Å; L153-I156 PolarHBondContact O-N 3.4Å; L153-V364 HydrophobicContact CD2-CG2 4.17Å; L153-F367 HydrophobicContact CD1-CB 4.34Å; L153-F367 HydrophobicContact CD1-CD2 4.34Å; L153-F367 HydrophobicContact CD2-CB 3.56Å; L153-F367 HydrophobicContact CD2-CD1 4.05Å; L153-F367 HydrophobicContact CD2-CD2 4.08Å; L153-F367 HydrophobicContact CD2-CG 3.63Å; L153-K377 VanDerWaalsContact O-CE 3.27Å; L153-K377 WeakPolarHBondContact O-CE 3.41Å; L153-K377 PolarHBondContact O-NZ 2.89Å; L153-M381 HydrophobicContact CB-CE 4.07Å; L153-M381 HydrophobicContact CB-CG 4.31Å; L153-M381 HydrophobicContact CD1-CG 4.42Å
154	F	80.8	Confident	77.1	Confident	145 Å²	145	73.7 Å²	73.7	64%	0.636	39%	0.39	S	S	*	.	H	α-helix	trans	-59.5	-37.6	174.2	-169.3	-96.9	0	0	0	112	F150 V152 I156 K377 M381	F150-F154 PolarHBondContact O-N 3.17Å; F150-F154 VanDerWaalsContact O-N 3.14Å; V152-F154 PolarHBondContact O-N 3.34Å; F154-I156 VanDerWaalsContact C-N 3.32Å; F154-I156 PolarHBondContact O-N 3.45Å; F154-K377 PolarHBondContact O-NZ 3.49Å; F154-M381 HydrophobicContact CB-CE 4.4Å
155	L	78.8	Confident	76.4	Confident	140 Å²	140	71 Å²	71	73%	0.733	38%	0.375	S	S	*	.	H	α-helix	trans	-73.3	-17.4	-178.3	-58.3	174	0	0	0	114	V152 L153 P157	V152-L155 WeakPolarHBondContact O-CB 3.28Å; V152-L155 PolarHBondContact O-N 2.82Å; L153-L155 PolarHBondContact O-N 2.7Å; L155-P157 WeakPolarHBondContact O-CD 3.38Å
156	I	75.9	Confident	76	Confident	17 Å²	17	79.7 Å²	79.7	9%	0.087	41%	0.408	C	S	.	.	S	Bend	trans	-80.3	120	-175.2	-43.1	-177.9	0	0	0	110.7	L153 F154 V158 L172 V364 K377	L153-I156 HydrophobicContact CD2-CD1 3.87Å; L153-I156 PolarHBondContact O-N 3.4Å; F154-I156 VanDerWaalsContact C-N 3.32Å; F154-I156 PolarHBondContact O-N 3.45Å; I156-V158 HydrophobicContact CB-CG2 4.16Å; I156-V158 HydrophobicContact CG2-CG2 3.5Å; I156-V158 VanDerWaalsContact CG2-CG2 3.5Å; I156-V158 PolarHBondContact O-N 2.98Å; I156-L172 HydrophobicContact CG2-CD1 4.49Å; I156-V364 HydrophobicContact CD1-CG1 4.4Å; I156-V364 HydrophobicContact CD1-CG2 4.13Å; I156-K377 PolarHBondContact O-NZ 3.4Å
157	P	70	Confident	75.7	Confident	106 Å²	106	81 Å²	81	69%	0.688	42%	0.417	S	S	*	.			trans	-84.6	71	-170.6	34.4	-36.7	0	0	0	113.1	L155	L155-P157 WeakPolarHBondContact O-CD 3.38Å
158	V	67.7	Low	75.6	Confident	10 Å²	10	81.6 Å²	81.6	6%	0.061	42%	0.415	C	S	.	.			trans	-97.3	13.6	-166.5	161.2	0	0	0	0	115	I156 H165 F367 V371 K377	I156-V158 HydrophobicContact CB-CG2 4.16Å; I156-V158 HydrophobicContact CG2-CG2 3.5Å; I156-V158 VanDerWaalsContact CG2-CG2 3.5Å; I156-V158 PolarHBondContact O-N 2.98Å; V158-H165 VanDerWaalsContact CA-NE2 3.32Å; V158-H165 WeakPolarHBondContact CA-NE2 3.46Å; V158-H165 WeakPolarHBondContact CB-NE2 3.22Å; V158-H165 WeakPolarHBondContact CG1-NE2 3.39Å; V158-H165 WeakPolarHBondContact CG2-NE2 3.44Å; V158-H165 PolarHBondContact O-CE1 3.13Å; V158-F367 HydrophobicContact CB-CE1 3.96Å; V158-F367 HydrophobicContact CB-CZ 3.96Å; V158-F367 HydrophobicContact CG1-CE1 3.66Å; V158-F367 HydrophobicContact CG1-CZ 3.58Å; V158-F367 HydrophobicContact CG2-CE1 3.66Å; V158-F367 HydrophobicContact CG2-CZ 4.17Å; V158-V371 HydrophobicContact CG1-CG1 4.01Å; V158-V371 HydrophobicContact CG1-CG2 3.98Å; V158-K377 HydrophobicContact CB-CD 4.49Å; V158-K377 HydrophobicContact CG1-CB 4.49Å
159	E	62.2	Low	75.7	Confident	142 Å²	142	81.1 Å²	81.1	66%	0.664	41%	0.409	S	S	*	.			trans	-99.3	18.7	-166.5	-59.4	-168.9	148.3	0	0	115.4	K377	E159-K377 HydrophobicContact CG-CB 4.17Å; E159-K377 HydrophobicContact CG-CD 3.88Å
160	S	53.3	Low	76.1	Confident	72 Å²	72	82.5 Å²	82.5	50%	0.503	42%	0.416	S	S	.	.			trans	-129.4	139.2	-178	-176	0	0	0	0	114	S162 H165	S160-S162 PolarHBondContact O-N 2.82Å; S160-S162 PolarHBondContact OG-N 2.83Å; S160-H165 WeakPolarHBondContact O-CB 3.31Å; S160-H165 PolarHBondContact O-ND1 2.95Å
161	N	58.3	Low	76.4	Confident	162 Å²	162	78.9 Å²	78.9	87%	0.866	40%	0.4	S	S	*	.			trans	-75.3	22.7	173.6	-77.4	-56.3	0	0	0	113.7
162	S	66.9	Low	76.7	Confident	46 Å²	46	72.6 Å²	72.6	32%	0.322	37%	0.373	S	S	.	.			trans	-69.2	145.5	179.4	176.3	0	0	0	0	112	S160 R164 H165	S160-S162 PolarHBondContact O-N 2.82Å; S160-S162 PolarHBondContact OG-N 2.83Å; S162-R164 PolarHBondContact O-N 3.35Å; S162-R164 PolarHBondContact OG-N 2.85Å; S162-H165 WeakPolarHBondContact O-CB 3.5Å; S162-H165 PolarHBondContact O-N 3.27Å
163	P	69.4	Low	77.2	Confident	108 Å²	108	70.6 Å²	70.6	70%	0.701	36%	0.361	S	S	*	.	H	α-helix	trans	-51.7	-38.9	171.9	-27.5	35.5	0	0	0	113.4	H165 R166 S167	P163-H165 PolarHBondContact O-N 3.45Å; P163-R166 WeakPolarHBondContact O-CB 3.35Å; P163-R166 PolarHBondContact O-N 2.88Å; P163-S167 PolarHBondContact O-N 3.45Å
164	R	73	Confident	77.7	Confident	167 Å²	167	70.5 Å²	70.5	63%	0.63	36%	0.36	S	S	*	.	H	α-helix	trans	-55.4	-35.6	175.9	-176.9	176.1	-177.3	152	4.8	112.6	S162 L168	S162-R164 PolarHBondContact O-N 3.35Å; S162-R164 PolarHBondContact OG-N 2.85Å; R164-L168 PolarHBondContact O-N 2.81Å; R164-L168 VanDerWaalsContact O-N 3.08Å
165	H	78.3	Confident	78.2	Confident	29 Å²	29	64.4 Å²	64.4	13%	0.134	33%	0.333	C	S	.	.	H	α-helix	trans	-73.6	-31.7	-179.1	-174.4	-135.8	0	0	0	112	V158 S160 S162 P163 L169	V158-H165 VanDerWaalsContact CA-NE2 3.32Å; V158-H165 WeakPolarHBondContact CA-NE2 3.46Å; V158-H165 WeakPolarHBondContact CB-NE2 3.22Å; V158-H165 WeakPolarHBondContact CG1-NE2 3.39Å; V158-H165 WeakPolarHBondContact CG2-NE2 3.44Å; V158-H165 PolarHBondContact O-CE1 3.13Å; S160-H165 WeakPolarHBondContact O-CB 3.31Å; S160-H165 PolarHBondContact O-ND1 2.95Å; S162-H165 WeakPolarHBondContact O-CB 3.5Å; S162-H165 PolarHBondContact O-N 3.27Å; P163-H165 PolarHBondContact O-N 3.45Å; H165-L169 WeakPolarHBondContact O-CB 3.29Å; H165-L169 PolarHBondContact O-N 3.48Å
166	R	83.2	Confident	78.8	Confident	183 Å²	183	57.9 Å²	57.9	69%	0.691	30%	0.3	S	S	*	.	H	α-helix	trans	-66.2	-45.9	172.4	-63.7	-175.5	-178.3	175	1.3	111.9	P163 L169 Q170	P163-R166 WeakPolarHBondContact O-CB 3.35Å; P163-R166 PolarHBondContact O-N 2.88Å; R166-L169 PolarHBondContact O-N 3.14Å; R166-Q170 WeakPolarHBondContact O-CG 3.39Å; R166-Q170 PolarHBondContact O-N 3.47Å
167	S	86.2	Confident	79.7	Confident	37 Å²	37	57.1 Å²	57.1	26%	0.259	30%	0.296	S	S	.	.	H	α-helix	trans	-58.7	-47.9	176.1	162.5	0	0	0	0	111.6	P163 L169 Q170 I171 Q447	P163-S167 PolarHBondContact O-N 3.45Å; S167-L169 VanDerWaalsContact C-N 3.34Å; S167-L169 PolarHBondContact O-N 2.86Å; S167-Q170 PolarHBondContact O-N 3.44Å; S167-I171 WeakPolarHBondContact O-CG1 3.23Å; S167-I171 PolarHBondContact O-N 3.5Å; S167-I171 VanDerWaalsContact O-N 3.09Å; S167-Q447 PolarHBondContact O-NE2 3.19Å; S167-Q447 PolarHBondContact OG-OE1 3.33Å
168	L	85.9	Confident	80.8	Confident	46 Å²	46	52 Å²	52	24%	0.241	26%	0.263	C	S	.	.	H	α-helix	trans	-60.6	-42.5	175	-179.9	64.3	0	0	0	112.1	V25 R164 Q170 I171 L172	V25-L168 HydrophobicContact CG1-CD1 4.3Å; R164-L168 PolarHBondContact O-N 2.81Å; R164-L168 VanDerWaalsContact O-N 3.08Å; L168-Q170 PolarHBondContact O-N 3.08Å; L168-I171 PolarHBondContact O-N 2.85Å; L168-L172 HydrophobicContact CD1-CD1 4.41Å; L168-L172 HydrophobicContact CD1-CG 4.3Å; L168-L172 HydrophobicContact CG-CD1 4.07Å; L168-L172 HydrophobicContact CG-CG 4.38Å; L168-L172 WeakPolarHBondContact O-CG 3.42Å; L168-L172 PolarHBondContact O-N 3.08Å
169	L	87.3	Confident	82	Confident	12 Å²	12	51.8 Å²	51.8	6%	0.063	26%	0.263	C	S	.	.	H	α-helix	trans	-62.9	-40.6	179.7	-171.6	66.8	0	0	0	111.8	H165 R166 S167 L172 L173 A368 V371 Q372	H165-L169 WeakPolarHBondContact O-CB 3.29Å; H165-L169 PolarHBondContact O-N 3.48Å; R166-L169 PolarHBondContact O-N 3.14Å; S167-L169 VanDerWaalsContact C-N 3.34Å; S167-L169 PolarHBondContact O-N 2.86Å; L169-L172 PolarHBondContact O-N 2.92Å; L169-L173 WeakPolarHBondContact O-CB 3.4Å; L169-L173 PolarHBondContact O-N 3.45Å; L169-A368 HydrophobicContact CD1-CB 3.82Å; L169-V371 HydrophobicContact CD1-CB 4.33Å; L169-V371 HydrophobicContact CD1-CG1 4.2Å; L169-V371 HydrophobicContact CD2-CG1 4.33Å; L169-Q372 HydrophobicContact CD2-CB 4.1Å
170	Q	89.9	Confident	83.5	Confident	31 Å²	31	45.1 Å²	45.1	15%	0.145	23%	0.232	C	C	.	.	H	α-helix	trans	-67.1	-37.5	174.9	-63.3	-65.7	-10.6	0	0	112.4	R166 S167 L168 L173 S174 L439 E451	R166-Q170 WeakPolarHBondContact O-CG 3.39Å; R166-Q170 PolarHBondContact O-N 3.47Å; S167-Q170 PolarHBondContact O-N 3.44Å; L168-Q170 PolarHBondContact O-N 3.08Å; Q170-L173 PolarHBondContact O-N 3.01Å; Q170-S174 WeakPolarHBondContact O-CB 3.08Å; Q170-S174 PolarHBondContact O-N 3.34Å; Q170-L439 HydrophobicContact CB-CD2 4.48Å; Q170-L439 WeakPolarHBondContact O-CD2 3.3Å; Q170-E451 HydrophobicContact CB-CG 4.18Å; Q170-E451 WeakPolarHBondContact CB-OE1 3.32Å
171	I	90.6	Very high	85.5	Confident	6 Å²	6	43.1 Å²	43.1	3%	0.031	22%	0.215	C	C	.	.	H	α-helix	trans	-66.8	-42	174.7	-66.7	159.1	0	0	0	111.4	V25 S167 L168 L173 S174 F175 L450 E451	V25-I171 HydrophobicContact CG1-CD1 4.04Å; V25-I171 HydrophobicContact CG2-CD1 3.99Å; S167-I171 WeakPolarHBondContact O-CG1 3.23Å; S167-I171 PolarHBondContact O-N 3.5Å; S167-I171 VanDerWaalsContact O-N 3.09Å; L168-I171 PolarHBondContact O-N 2.85Å; I171-L173 VanDerWaalsContact C-N 3.32Å; I171-S174 PolarHBondContact O-N 2.85Å; I171-S174 PolarHBondContact O-OG 3.41Å; I171-F175 WeakPolarHBondContact O-CB 3.32Å; I171-F175 PolarHBondContact O-N 3.28Å; I171-L450 HydrophobicContact CD1-CB 4.06Å; I171-L450 HydrophobicContact CD1-CD1 4.35Å; I171-L450 HydrophobicContact CG1-CB 4.16Å; I171-E451 HydrophobicContact CG1-CG 4.46Å
172	L	89.5	Confident	87.2	Confident	17 Å²	17	35.5 Å²	35.5	9%	0.089	18%	0.175	C	C	.	.	H	α-helix	trans	-65	-38.2	174	-70.4	173.5	0	0	0	111.5	W18 I156 L168 L169 F175 A176 V364 A368	W18-L172 HydrophobicContact CH2-CD2 4.42Å; I156-L172 HydrophobicContact CG2-CD1 4.49Å; L168-L172 HydrophobicContact CD1-CD1 4.41Å; L168-L172 HydrophobicContact CD1-CG 4.3Å; L168-L172 HydrophobicContact CG-CD1 4.07Å; L168-L172 HydrophobicContact CG-CG 4.38Å; L168-L172 WeakPolarHBondContact O-CG 3.42Å; L168-L172 PolarHBondContact O-N 3.08Å; L169-L172 PolarHBondContact O-N 2.92Å; L172-F175 PolarHBondContact O-N 3.14Å; L172-A176 WeakPolarHBondContact O-CB 3.4Å; L172-A176 PolarHBondContact O-N 3.38Å; L172-V364 HydrophobicContact CD2-CG1 3.87Å; L172-A368 HydrophobicContact CB-CB 3.8Å
173	L	91.1	Very high	88.4	Confident	4 Å²	4	33.3 Å²	33.3	2%	0.021	16%	0.16	C	C	.	.	H	α-helix	trans	-68.3	-35.8	176.9	-178.4	63.9	0	0	0	112.2	L169 Q170 I171 A176 S177 I369 Q372 V435 E438 L439	L169-L173 WeakPolarHBondContact O-CB 3.4Å; L169-L173 PolarHBondContact O-N 3.45Å; Q170-L173 PolarHBondContact O-N 3.01Å; I171-L173 VanDerWaalsContact C-N 3.32Å; L173-A176 WeakPolarHBondContact O-CB 3.39Å; L173-A176 PolarHBondContact O-N 3.02Å; L173-S177 PolarHBondContact O-N 2.95Å; L173-I369 HydrophobicContact CD1-CB 4.48Å; L173-I369 HydrophobicContact CD1-CD1 4.32Å; L173-I369 HydrophobicContact CD1-CG1 3.4Å; L173-I369 VanDerWaalsContact CD1-CG1 3.4Å; L173-Q372 HydrophobicContact CD2-CG 4.42Å; L173-V435 HydrophobicContact CD1-CB 4.17Å; L173-V435 HydrophobicContact CD1-CG1 3.47Å; L173-V435 VanDerWaalsContact CD1-CG1 3.47Å; L173-V435 HydrophobicContact CD1-CG2 3.88Å; L173-V435 HydrophobicContact CD2-CG1 4.47Å; L173-V435 HydrophobicContact CG-CG1 3.64Å; L173-V435 WeakPolarHBondContact O-CG1 3.14Å; L173-E438 HydrophobicContact CD2-CB 3.93Å; L173-E438 HydrophobicContact CD2-CG 3.65Å; L173-L439 HydrophobicContact CB-CD2 4.28Å; L173-L439 HydrophobicContact CD2-CD2 4.16Å; L173-L439 HydrophobicContact CG-CD2 4.12Å
174	S	93.2	Very high	89.5	Confident	0 Å²	0	28.2 Å²	28.2	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-70	-43	173.9	81.6	0	0	0	0	111.4	Q170 I171 A176 S177 G178 E451 G454 L455	Q170-S174 WeakPolarHBondContact O-CB 3.08Å; Q170-S174 PolarHBondContact O-N 3.34Å; I171-S174 PolarHBondContact O-N 2.85Å; I171-S174 PolarHBondContact O-OG 3.41Å; S174-A176 VanDerWaalsContact C-N 3.33Å; S174-A176 PolarHBondContact O-N 3.25Å; S174-S177 WeakPolarHBondContact O-CB 3.33Å; S174-S177 PolarHBondContact O-N 2.82Å; S174-G178 PolarHBondContact O-N 3.23Å; S174-E451 WeakPolarHBondContact CB-O 3.41Å; S174-E451 WeakPolarHBondContact OG-CA 3.47Å; S174-E451 PolarHBondContact OG-O 3.13Å; S174-G454 WeakPolarHBondContact OG-CA 3.45Å; S174-L455 WeakPolarHBondContact O-CA 3.28Å; S174-L455 WeakPolarHBondContact O-CB 3.43Å; S174-L455 PolarHBondContact OG-N 2.99Å
175	F	92.4	Very high	90.5	Very high	17 Å²	17	25.7 Å²	25.7	8%	0.075	12%	0.12	C	C	.	.	H	α-helix	trans	-57.1	-43.7	170.2	179.3	-92.9	0	0	0	112.1	I171 L172 S177 G178 G179 P361 G454 M461	I171-F175 WeakPolarHBondContact O-CB 3.32Å; I171-F175 PolarHBondContact O-N 3.28Å; L172-F175 PolarHBondContact O-N 3.14Å; F175-S177 PolarHBondContact O-N 2.74Å; F175-G178 PolarHBondContact O-N 3.11Å; F175-G179 PolarHBondContact O-N 3.48Å; F175-P361 HydrophobicContact CE1-CB 4.11Å; F175-P361 HydrophobicContact CZ-CB 4.27Å; F175-G454 VanDerWaalsContact CA-O 3.31Å; F175-G454 WeakPolarHBondContact CA-O 3.45Å; F175-M461 HydrophobicContact CE2-SD 4.36Å; F175-M461 HydrophobicContact CZ-SD 3.64Å
176	A	90.4	Very high	91.1	Very high	4 Å²	4	27.6 Å²	27.6	3%	0.033	13%	0.131	C	C	.	.	H	α-helix	trans	-56.6	-48.4	173.4	0	0	0	0	0	112	L172 L173 S174 G178 G179 L180 I369	L172-A176 WeakPolarHBondContact O-CB 3.4Å; L172-A176 PolarHBondContact O-N 3.38Å; L173-A176 WeakPolarHBondContact O-CB 3.39Å; L173-A176 PolarHBondContact O-N 3.02Å; S174-A176 VanDerWaalsContact C-N 3.33Å; S174-A176 PolarHBondContact O-N 3.25Å; A176-G178 VanDerWaalsContact C-N 3.29Å; A176-G178 PolarHBondContact O-N 2.89Å; A176-G179 PolarHBondContact O-N 3.33Å; A176-L180 WeakPolarHBondContact O-CB 3.35Å; A176-L180 WeakPolarHBondContact O-CG 3.24Å; A176-L180 PolarHBondContact O-N 3.28Å; A176-I369 HydrophobicContact CB-CD1 4.1Å
177	S	93.9	Very high	91.2	Very high	0 Å²	0	20.6 Å²	20.6	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-59.2	-41.2	176.9	-161.5	0	0	0	0	112.1	L173 S174 F175 L181 L436	L173-S177 PolarHBondContact O-N 2.95Å; S174-S177 WeakPolarHBondContact O-CB 3.33Å; S174-S177 PolarHBondContact O-N 2.82Å; F175-S177 PolarHBondContact O-N 2.74Å; S177-L181 WeakPolarHBondContact O-CB 3.43Å; S177-L181 VanDerWaalsContact O-CG 3.25Å; S177-L181 WeakPolarHBondContact O-CG 3.3Å; S177-L181 PolarHBondContact O-N 3.43Å; S177-L436 WeakPolarHBondContact OG-CD1 3.31Å
178	G	94.3	Very high	91.3	Very high	0 Å²	0	18.9 Å²	18.9	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-65.5	-41.5	175.7	0	0	0	0	0	113.3	S174 F175 A176 G182 L455 V459	S174-G178 PolarHBondContact O-N 3.23Å; F175-G178 PolarHBondContact O-N 3.11Å; A176-G178 VanDerWaalsContact C-N 3.29Å; A176-G178 PolarHBondContact O-N 2.89Å; G178-G182 WeakPolarHBondContact O-CA 3.46Å; G178-G182 PolarHBondContact O-N 3.29Å; G178-L455 WeakPolarHBondContact CA-O 3.41Å; G178-V459 WeakPolarHBondContact O-CG2 3.34Å; G178-V459 PolarHBondContact O-N 2.78Å
179	G	92.7	Very high	91.5	Very high	5 Å²	5	18 Å²	18	5%	0.052	9%	0.089	C	C	.	.	H	α-helix	trans	-63.5	-55.3	174.8	0	0	0	0	0	112	F175 A176 L181 G182 D183 M462	F175-G179 PolarHBondContact O-N 3.48Å; A176-G179 PolarHBondContact O-N 3.33Å; G179-L181 VanDerWaalsContact C-N 3.33Å; G179-L181 PolarHBondContact O-N 3.45Å; G179-G182 CarbonylContact O-C 3.58Å; G179-G182 PolarHBondContact O-N 2.93Å; G179-G182 VanDerWaalsContact O-N 3.09Å; G179-D183 WeakPolarHBondContact O-CB 3.27Å; G179-D183 PolarHBondContact O-N 3.18Å; G179-M462 WeakPolarHBondContact O-CG 3.04Å
180	L	93.3	Very high	91.5	Very high	2 Å²	2	19.6 Å²	19.6	1%	0.01	10%	0.1	C	C	.	.	H	α-helix	trans	-57.7	-40	179.1	-68.7	170.6	0	0	0	113.2	A176 A184 I369 F427 V430 A431	A176-L180 WeakPolarHBondContact O-CB 3.35Å; A176-L180 WeakPolarHBondContact O-CG 3.24Å; A176-L180 PolarHBondContact O-N 3.28Å; L180-A184 WeakPolarHBondContact O-CB 3.45Å; L180-A184 PolarHBondContact O-N 2.89Å; L180-A184 VanDerWaalsContact O-N 3.14Å; L180-I369 HydrophobicContact CD1-CD1 4.13Å; L180-F427 HydrophobicContact CB-CD2 4.5Å; L180-F427 HydrophobicContact CD2-CD1 3.98Å; L180-F427 HydrophobicContact CD2-CD2 3.67Å; L180-F427 HydrophobicContact CD2-CE1 3.91Å; L180-F427 HydrophobicContact CD2-CE2 3.62Å; L180-F427 HydrophobicContact CD2-CG 3.82Å; L180-F427 HydrophobicContact CD2-CZ 3.72Å; L180-V430 HydrophobicContact CD1-CG1 3.96Å; L180-A431 HydrophobicContact CB-CB 4.07Å; L180-A431 HydrophobicContact CD1-CB 4.49Å
181	L	95.3	Very high	91.1	Very high	30 Å²	30	21.8 Å²	21.8	16%	0.157	11%	0.11	C	C	.	.	H	α-helix	trans	-73.1	-39.8	174.5	-70.2	171.2	0	0	0	112	S177 G179 F185 I428 A431 T432 L436	S177-L181 WeakPolarHBondContact O-CB 3.43Å; S177-L181 VanDerWaalsContact O-CG 3.25Å; S177-L181 WeakPolarHBondContact O-CG 3.3Å; S177-L181 PolarHBondContact O-N 3.43Å; G179-L181 VanDerWaalsContact C-N 3.33Å; G179-L181 PolarHBondContact O-N 3.45Å; L181-F185 HydrophobicContact CD2-CD2 4.46Å; L181-F185 HydrophobicContact CD2-CE2 4.11Å; L181-F185 WeakPolarHBondContact O-CB 3.46Å; L181-F185 WeakPolarHBondContact O-CD2 3.47Å; L181-F185 PolarHBondContact O-N 3.35Å; L181-I428 HydrophobicContact CD2-CG1 4.38Å; L181-A431 HydrophobicContact CD1-CB 4.28Å; L181-A431 HydrophobicContact CD2-CB 3.9Å; L181-A431 HydrophobicContact CG-CB 3.69Å; L181-T432 HydrophobicContact CD2-CG2 4.15Å; L181-L436 HydrophobicContact CD1-CD1 4.07Å
182	G	93.8	Very high	90.7	Very high	2 Å²	2	22.5 Å²	22.5	2%	0.021	12%	0.117	C	C	.	.	H	α-helix	trans	-59	-48.7	175.7	0	0	0	0	0	111.4	G178 G179 L186	G178-G182 WeakPolarHBondContact O-CA 3.46Å; G178-G182 PolarHBondContact O-N 3.29Å; G179-G182 CarbonylContact O-C 3.58Å; G179-G182 PolarHBondContact O-N 2.93Å; G179-G182 VanDerWaalsContact O-N 3.09Å; G182-L186 WeakPolarHBondContact O-CA 3.31Å; G182-L186 WeakPolarHBondContact O-CB 3.44Å; G182-L186 VanDerWaalsContact O-CG 3.24Å; G182-L186 WeakPolarHBondContact O-CG 3.37Å; G182-L186 PolarHBondContact O-N 3.34Å
183	D	91.6	Very high	90.5	Very high	0 Å²	0	24.7 Å²	24.7	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-61.2	-53	177	176.2	59.6	0	0	0	112.3	G179 F185 H187 L188 H329 F427 M462	G179-D183 WeakPolarHBondContact O-CB 3.27Å; G179-D183 PolarHBondContact O-N 3.18Å; D183-F185 VanDerWaalsContact C-N 3.3Å; D183-F185 PolarHBondContact O-N 3.03Å; D183-H187 WeakPolarHBondContact O-CA 3.37Å; D183-H187 WeakPolarHBondContact O-CB 3.49Å; D183-H187 PolarHBondContact O-N 2.87Å; D183-H187 WeakPolarHBondContact OD1-CB 3.25Å; D183-H187 IonicContact OD1-CD2 3.32Å; D183-H187 IonicContact OD1-CG 2.77Å; D183-L188 PolarHBondContact O-N 3.05Å; D183-L188 WeakPolarHBondContact OD2-CD1 3.47Å; D183-L188 VanDerWaalsContact OD2-CG 3.32Å; D183-L188 WeakPolarHBondContact OD2-CG 3.39Å; D183-H329 IonicContact OD1-CE1 3.88Å; D183-H329 IonicContact OD2-CE1 3.99Å; D183-H329 PolarHBondContact OD2-CE1 3.37Å; D183-H329 IonicContact OD2-ND1 3.14Å; D183-H329 PolarHBondContact OD2-ND1 3.47Å; D183-F427 HydrophobicContact CB-CD2 4.23Å; D183-F427 HydrophobicContact CB-CE2 4.33Å; D183-F427 WeakPolarHBondContact OD2-CD2 3.48Å; D183-F427 WeakPolarHBondContact OD2-CE2 3.28Å; D183-M462 HydrophobicContact CB-CE 3.81Å; D183-M462 HydrophobicContact CB-SD 4.42Å
184	A	93	Very high	89.7	Confident	0 Å²	0	29.9 Å²	29.9	0%	0	15%	0.153	C	C	.	.	I	π-helix	trans	-55.9	-43.6	179.8	0	0	0	0	0	112.7	L180 I189 A424 F427 I428	L180-A184 WeakPolarHBondContact O-CB 3.45Å; L180-A184 PolarHBondContact O-N 2.89Å; L180-A184 VanDerWaalsContact O-N 3.14Å; A184-I189 VanDerWaalsContact O-CB 3.27Å; A184-I189 WeakPolarHBondContact O-CB 3.41Å; A184-I189 VanDerWaalsContact O-CD1 3.32Å; A184-I189 WeakPolarHBondContact O-CD1 3.33Å; A184-I189 WeakPolarHBondContact O-CG1 3.46Å; A184-I189 PolarHBondContact O-N 3.46Å; A184-I189 VanDerWaalsContact O-N 3.09Å; A184-A424 HydrophobicContact CB-CB 4Å; A184-F427 HydrophobicContact CB-CB 4.08Å; A184-I428 HydrophobicContact CB-CD1 4.15Å; A184-I428 HydrophobicContact CB-CG1 3.76Å
185	F	94.6	Very high	88	Confident	115 Å²	115	34 Å²	34	50%	0.504	18%	0.18	S	C	.	.	I	π-helix	trans	-92.1	-23.5	-174.8	-76.8	-70.1	0	0	0	115.6	L181 D183 I189 P190 I428	L181-F185 HydrophobicContact CD2-CD2 4.46Å; L181-F185 HydrophobicContact CD2-CE2 4.11Å; L181-F185 WeakPolarHBondContact O-CB 3.46Å; L181-F185 WeakPolarHBondContact O-CD2 3.47Å; L181-F185 PolarHBondContact O-N 3.35Å; D183-F185 VanDerWaalsContact C-N 3.3Å; D183-F185 PolarHBondContact O-N 3.03Å; F185-I189 HydrophobicContact CD1-CD1 4.08Å; F185-I189 HydrophobicContact CE1-CD1 4.25Å; F185-P190 WeakPolarHBondContact O-CD 3.44Å; F185-P190 WeakPolarHBondContact O-CG 3.33Å; F185-I428 HydrophobicContact CE1-CD1 4.21Å; F185-I428 HydrophobicContact CE2-CD1 3.86Å; F185-I428 HydrophobicContact CE2-CG1 3.86Å; F185-I428 HydrophobicContact CZ-CD1 3.66Å; F185-I428 HydrophobicContact CZ-CG1 4.16Å
186	L	91.1	Very high	86.1	Confident	69 Å²	69	37.1 Å²	37.1	36%	0.361	19%	0.194	S	C	.	.	I	π-helix	trans	-111.1	-22	-174	-51.9	174.3	0	0	0	113.5	G182 M462 V463	G182-L186 WeakPolarHBondContact O-CA 3.31Å; G182-L186 WeakPolarHBondContact O-CB 3.44Å; G182-L186 VanDerWaalsContact O-CG 3.24Å; G182-L186 WeakPolarHBondContact O-CG 3.37Å; G182-L186 PolarHBondContact O-N 3.34Å; L186-M462 HydrophobicContact CD1-CB 4.41Å; L186-V463 HydrophobicContact CD1-CB 4.43Å; L186-V463 HydrophobicContact CD1-CG2 3.44Å; L186-V463 VanDerWaalsContact CD1-CG2 3.44Å
187	H	85.4	Confident	83.6	Confident	35 Å²	35	42.1 Å²	42.1	16%	0.162	23%	0.229	C	C	.	.	I	π-helix	trans	-113.6	-68.3	178.9	-172.4	75.6	0	0	0	110.7	D183 I189 P190 H191 H358 E469	D183-H187 WeakPolarHBondContact O-CA 3.37Å; D183-H187 WeakPolarHBondContact O-CB 3.49Å; D183-H187 PolarHBondContact O-N 2.87Å; D183-H187 WeakPolarHBondContact OD1-CB 3.25Å; D183-H187 IonicContact OD1-CD2 3.32Å; D183-H187 IonicContact OD1-CG 2.77Å; H187-I189 PolarHBondContact O-N 3.38Å; H187-P190 WeakPolarHBondContact O-CD 3.39Å; H187-H191 VanDerWaalsContact O-CB 3.24Å; H187-H191 WeakPolarHBondContact O-CB 3.34Å; H187-H191 PolarHBondContact O-N 3.19Å; H187-H358 AromaticContact NE2-CE1 3.96Å; H187-E469 VanDerWaalsContact CE1-CD 3.44Å; H187-E469 IonicContact CE1-OE1 3.71Å; H187-E469 PolarHBondContact CE1-OE1 3.4Å; H187-E469 IonicContact CE1-OE2 3.79Å; H187-E469 PolarHBondContact CE1-OE2 2.92Å; H187-E469 VanDerWaalsContact CE1-OE2 3.32Å; H187-E469 IonicContact CG-OE2 3.61Å; H187-E469 VanDerWaalsContact ND1-CD 3.31Å; H187-E469 IonicContact ND1-OE1 3.76Å; H187-E469 PolarHBondContact ND1-OE1 3.38Å; H187-E469 IonicContact ND1-OE2 3.21Å; H187-E469 PolarHBondContact ND1-OE2 3.47Å
188	L	88.1	Confident	81.2	Confident	2 Å²	2	49.6 Å²	49.6	1%	0.01	26%	0.263	C	S	.	.	I	π-helix	trans	-63.2	-48.7	-171.3	-61.6	-179.5	0	0	0	114.5	D183 A192 L420 T423 A424 F427	D183-L188 PolarHBondContact O-N 3.05Å; D183-L188 WeakPolarHBondContact OD2-CD1 3.47Å; D183-L188 VanDerWaalsContact OD2-CG 3.32Å; D183-L188 WeakPolarHBondContact OD2-CG 3.39Å; L188-A192 WeakPolarHBondContact O-CB 3.42Å; L188-A192 PolarHBondContact O-N 2.97Å; L188-A192 VanDerWaalsContact O-N 3.14Å; L188-L420 HydrophobicContact CD2-CD2 3.69Å; L188-T423 HydrophobicContact CD1-CG2 3.88Å; L188-A424 HydrophobicContact CB-CB 3.78Å; L188-A424 HydrophobicContact CD1-CB 3.91Å; L188-F427 HydrophobicContact CD1-CD2 4.36Å
189	I	90.5	Very high	78.4	Confident	28 Å²	28	58.7 Å²	58.7	14%	0.144	31%	0.306	C	S	.	.	H	α-helix	trans	-68.3	-48.5	-179.9	-72.8	167.8	0	0	0	111.8	A184 F185 H187 H191 A192 L193 V219 V223 A424 I428	A184-I189 VanDerWaalsContact O-CB 3.27Å; A184-I189 WeakPolarHBondContact O-CB 3.41Å; A184-I189 VanDerWaalsContact O-CD1 3.32Å; A184-I189 WeakPolarHBondContact O-CD1 3.33Å; A184-I189 WeakPolarHBondContact O-CG1 3.46Å; A184-I189 PolarHBondContact O-N 3.46Å; A184-I189 VanDerWaalsContact O-N 3.09Å; F185-I189 HydrophobicContact CD1-CD1 4.08Å; F185-I189 HydrophobicContact CE1-CD1 4.25Å; H187-I189 PolarHBondContact O-N 3.38Å; I189-H191 PolarHBondContact O-N 2.86Å; I189-A192 PolarHBondContact O-N 3.26Å; I189-L193 HydrophobicContact CG2-CD1 3.85Å; I189-L193 HydrophobicContact CG2-CG 4.47Å; I189-L193 WeakPolarHBondContact O-CG 3.38Å; I189-L193 PolarHBondContact O-N 3.47Å; I189-L193 VanDerWaalsContact O-N 3.15Å; I189-V219 HydrophobicContact CG2-CG1 4.34Å; I189-V223 HydrophobicContact CD1-CG1 4.37Å; I189-V223 HydrophobicContact CD1-CG2 3.85Å; I189-V223 HydrophobicContact CG1-CG2 3.8Å; I189-A424 HydrophobicContact CD1-CB 4.19Å; I189-A424 HydrophobicContact CG1-CB 3.8Å; I189-I428 HydrophobicContact CD1-CD1 4.22Å
190	P	87	Confident	75.8	Confident	44 Å²	44	64.9 Å²	64.9	29%	0.286	34%	0.342	S	S	.	.	H	α-helix	trans	-58.6	-44.8	175.8	-29	39.1	0	0	0	113.2	F185 H187 A192 L193 E194	F185-P190 WeakPolarHBondContact O-CD 3.44Å; F185-P190 WeakPolarHBondContact O-CG 3.33Å; H187-P190 WeakPolarHBondContact O-CD 3.39Å; P190-A192 VanDerWaalsContact C-N 3.27Å; P190-A192 PolarHBondContact O-N 2.91Å; P190-L193 WeakPolarHBondContact O-CA 3.13Å; P190-L193 WeakPolarHBondContact O-CB 3.27Å; P190-L193 PolarHBondContact O-N 3.03Å; P190-E194 PolarHBondContact O-N 3.39Å
191	H	81.2	Confident	73.3	Confident	77 Å²	77	72.8 Å²	72.8	36%	0.356	38%	0.384	S	S	.	.	H	α-helix	trans	-63.5	-34.1	179.2	-154	78.1	0	0	0	112.1	H187 I189 L193 L420	H187-H191 VanDerWaalsContact O-CB 3.24Å; H187-H191 WeakPolarHBondContact O-CB 3.34Å; H187-H191 PolarHBondContact O-N 3.19Å; I189-H191 PolarHBondContact O-N 2.86Å; H191-L193 VanDerWaalsContact C-N 3.29Å; H191-L193 PolarHBondContact O-N 3.21Å; H191-L420 HydrophobicContact CB-CD1 4.48Å
192	A	82.9	Confident	70.5	Confident	22 Å²	22	80 Å²	80	18%	0.182	42%	0.417	C	S	.	.	H	α-helix	trans	-71.1	-19.9	172.4	0	0	0	0	0	114.3	L188 I189 P190 V219 L420 P421	L188-A192 WeakPolarHBondContact O-CB 3.42Å; L188-A192 PolarHBondContact O-N 2.97Å; L188-A192 VanDerWaalsContact O-N 3.14Å; I189-A192 PolarHBondContact O-N 3.26Å; P190-A192 VanDerWaalsContact C-N 3.27Å; P190-A192 PolarHBondContact O-N 2.91Å; A192-V219 HydrophobicContact CB-CG1 4.24Å; A192-V219 HydrophobicContact CB-CG2 3.92Å; A192-V219 VanDerWaalsContact O-CG2 3.26Å; A192-V219 WeakPolarHBondContact O-CG2 3.35Å; A192-L420 HydrophobicContact CB-CB 4.27Å; A192-P421 HydrophobicContact CB-CB 4.44Å; A192-P421 HydrophobicContact CB-CG 4.14Å
193	L	85.5	Confident	68.1	Low	62 Å²	62	88.8 Å²	88.8	33%	0.325	46%	0.457	S	S	.	.	H	α-helix	trans	-91.6	-14.6	179.6	-72.8	170.2	0	0	0	113.8	I189 P190 H191 P195 I216 V219	I189-L193 HydrophobicContact CG2-CD1 3.85Å; I189-L193 HydrophobicContact CG2-CG 4.47Å; I189-L193 WeakPolarHBondContact O-CG 3.38Å; I189-L193 PolarHBondContact O-N 3.47Å; I189-L193 VanDerWaalsContact O-N 3.15Å; P190-L193 WeakPolarHBondContact O-CA 3.13Å; P190-L193 WeakPolarHBondContact O-CB 3.27Å; P190-L193 PolarHBondContact O-N 3.03Å; H191-L193 VanDerWaalsContact C-N 3.29Å; H191-L193 PolarHBondContact O-N 3.21Å; L193-P195 WeakPolarHBondContact O-CD 3.03Å; L193-I216 HydrophobicContact CD2-CB 4.31Å; L193-I216 HydrophobicContact CD2-CG1 3.94Å; L193-V219 HydrophobicContact CD2-CB 3.86Å; L193-V219 HydrophobicContact CD2-CG1 3.96Å; L193-V219 HydrophobicContact CD2-CG2 3.86Å; L193-V219 HydrophobicContact CG-CB 4.45Å; L193-V219 HydrophobicContact CG-CG1 4.06Å; L193-V219 HydrophobicContact CG-CG2 4.31Å
194	E	73.1	Confident	65.5	Low	113 Å²	113	94.5 Å²	94.5	53%	0.528	49%	0.494	S	S	.	.			trans	-93.4	97.9	-179.5	-72	-166.1	-175	0	0	112.4	P190 H196	P190-E194 PolarHBondContact O-N 3.39Å; E194-H196 PolarHBondContact O-N 3.47Å; E194-H196 IonicContact OE2-CE1 3.51Å; E194-H196 PolarHBondContact OE2-CE1 2.86Å
195	P	57.1	Low	63	Low	88 Å²	88	97.8 Å²	97.8	57%	0.571	53%	0.528	S	S	*	.			trans	-71.3	99.6	167.5	30.1	-34.7	0	0	0	109.3	L193 S197	L193-P195 WeakPolarHBondContact O-CD 3.03Å; P195-S197 VanDerWaalsContact C-N 3.33Å; P195-S197 PolarHBondContact O-N 2.85Å
196	H	53.3	Low	60.7	Low	82 Å²	82	101.2 Å²	101.2	38%	0.38	55%	0.546	S	S	.	.			trans	-63.4	93.3	169.9	-72.1	-11.5	0	0	0	110.4	E194 H198 A411	E194-H196 PolarHBondContact O-N 3.47Å; E194-H196 IonicContact OE2-CE1 3.51Å; E194-H196 PolarHBondContact OE2-CE1 2.86Å; H196-H198 VanDerWaalsContact C-N 3.34Å; H196-H198 PolarHBondContact O-N 3.45Å; H196-A411 PolarHBondContact CD2-O 3.01Å
197	S	38.4	Very low	58.1	Low	108 Å²	108	101.5 Å²	101.5	76%	0.755	57%	0.565	S	S	*	*			trans	-71.1	82.3	-176.4	58.7	0	0	0	0	111.7	P195 H199	P195-S197 VanDerWaalsContact C-N 3.33Å; P195-S197 PolarHBondContact O-N 2.85Å; S197-H199 PolarHBondContact O-N 3.2Å
198	H	42.9	Very low	56	Low	157 Å²	157	108.4 Å²	108.4	73%	0.727	60%	0.597	S	S	*	*			trans	-65.6	120.3	166.1	-82.8	-67	0	0	0	110	H196 T200	H196-H198 VanDerWaalsContact C-N 3.34Å; H196-H198 PolarHBondContact O-N 3.45Å; H198-T200 PolarHBondContact O-N 2.85Å
199	H	35.3	Very low	53.6	Low	191 Å²	191	113 Å²	113	88%	0.884	63%	0.629	S	S	*	*			trans	-51.1	96.6	180	-67.5	-88.6	0	0	0	113.1	S197	S197-H199 PolarHBondContact O-N 3.2Å
200	T	39.5	Very low	51.2	Low	135 Å²	135	120.6 Å²	120.6	83%	0.828	66%	0.664	S	S	*	*	P	Polyproline II helix	trans	-81.6	129	153.3	46.4	0	0	0	0	108.3	H198	H198-T200 PolarHBondContact O-N 2.85Å
201	L	40.8	Very low	49.3	Very low	168 Å²	168	123.2 Å²	123.2	88%	0.88	68%	0.683	S	S	*	*	P	Polyproline II helix	trans	-61.8	151.6	-177.1	-79.1	155.3	0	0	0	111.9
202	E	35.3	Very low	47.9	Very low	182 Å²	182	123.2 Å²	123.2	85%	0.85	70%	0.704	S	S	*	*	P	Polyproline II helix	trans	-48.4	130.5	-167.8	-53.9	-174.1	154.9	0	0	115.2
203	Q	43	Very low	46.7	Very low	186 Å²	186	129.8 Å²	129.8	87%	0.869	73%	0.731	S	S	*	*			trans	-130.6	105.3	150.3	-72.2	-160.9	36.4	0	0	109.8	G205	Q203-G205 PolarHBondContact O-N 3.5Å
204	P	37.5	Very low	45.9	Very low	120 Å²	120	128.5 Å²	128.5	78%	0.779	73%	0.733	S	S	*	*			trans	-78.7	70.3	176.1	31.6	-33.8	0	0	0	111.3
205	G	41.6	Very low	46.1	Very low	69 Å²	69	126 Å²	126	71%	0.711	73%	0.726	S	S	*	*			trans	-97	117.3	176.3	0	0	0	0	0	112.3	Q203	Q203-G205 PolarHBondContact O-N 3.5Å
206	H	44.9	Very low	47.4	Very low	188 Å²	188	127 Å²	127	87%	0.87	73%	0.725	S	S	*	*			trans	-73	127.6	-176.8	-71.9	45.1	0	0	0	112.6
207	G	37.8	Very low	49	Very low	74 Å²	74	128.3 Å²	128.3	76%	0.763	74%	0.735	S	S	*	*			trans	-161.3	113.1	170.2	0	0	0	0	0	111
208	H	39.7	Very low	51.3	Low	181 Å²	181	125.7 Å²	125.7	84%	0.838	72%	0.717	S	S	*	*			trans	-79.4	155.9	-172.5	-66.2	-72.4	0	0	0	114
209	S	37.7	Very low	53.5	Low	98 Å²	98	118.6 Å²	118.6	69%	0.685	68%	0.684	S	S	*	*			trans	103.3	127.2	143.9	81.7	0	0	0	0	120.3
210	H	40.8	Very low	56.2	Low	188 Å²	188	111.4 Å²	111.4	87%	0.87	66%	0.661	S	S	*	*			trans	50.4	83.3	159.8	-47.8	-70.3	0	0	0	120.5
211	S	47	Very low	58.8	Low	98 Å²	98	109.8 Å²	109.8	69%	0.685	65%	0.647	S	S	*	*			trans	-150.9	5.7	168	61.5	0	0	0	0	119.2	Q213 G214	S211-Q213 PolarHBondContact O-N 3.18Å; S211-G214 PolarHBondContact O-N 3Å
212	G	52.6	Low	61.2	Low	77 Å²	77	106.5 Å²	106.5	79%	0.794	62%	0.623	S	S	*	*	T	Hydrogen-bonded Turn	trans	-61.9	-14.3	178.4	0	0	0	0	0	115.8
213	Q	57.9	Low	64	Low	160 Å²	160	98.6 Å²	98.6	75%	0.748	59%	0.587	S	S	*	*	T	Hydrogen-bonded Turn	trans	-102.5	-3.1	176.1	-70	174.8	-23.9	0	0	113.5	S211 I216 L217	S211-Q213 PolarHBondContact O-N 3.18Å; Q213-I216 PolarHBondContact O-N 3.36Å; Q213-L217 WeakPolarHBondContact O-CB 3.4Å; Q213-L217 PolarHBondContact O-N 2.91Å
214	G	68.4	Low	66.5	Low	36 Å²	36	94.4 Å²	94.4	37%	0.371	57%	0.57	S	S	.	*	H	α-helix	trans	-56.6	-54.9	-173.6	0	0	0	0	0	113.8	S211 L217 S218	S211-G214 PolarHBondContact O-N 3Å; G214-L217 PolarHBondContact O-N 3.28Å; G214-S218 WeakPolarHBondContact O-CB 3.11Å; G214-S218 PolarHBondContact O-N 3.44Å; G214-S218 PolarHBondContact O-OG 3.11Å
215	P	75.8	Confident	69.2	Low	59 Å²	59	90.9 Å²	90.9	38%	0.383	55%	0.548	S	S	.	.	H	α-helix	trans	-61.6	-44.9	178.6	-24.2	34.8	0	0	0	112.9	L217 S218 V219	P215-L217 PolarHBondContact O-N 3.31Å; P215-S218 PolarHBondContact O-N 3.21Å; P215-S218 PolarHBondContact O-OG 3.31Å; P215-V219 WeakPolarHBondContact O-CB 3.17Å; P215-V219 VanDerWaalsContact O-CG2 3.29Å; P215-V219 WeakPolarHBondContact O-CG2 3.49Å; P215-V219 PolarHBondContact O-N 3Å
216	I	84.8	Confident	71.6	Confident	109 Å²	109	87.6 Å²	87.6	56%	0.559	51%	0.514	S	S	*	.	H	α-helix	trans	-62.7	-44	-178.5	-61.2	163.5	0	0	0	110.8	L193 Q213 G220	L193-I216 HydrophobicContact CD2-CB 4.31Å; L193-I216 HydrophobicContact CD2-CG1 3.94Å; Q213-I216 PolarHBondContact O-N 3.36Å; I216-G220 PolarHBondContact O-N 2.81Å
217	L	86.7	Confident	74	Confident	111 Å²	111	80.9 Å²	80.9	58%	0.581	49%	0.485	S	S	*	.	H	α-helix	trans	-66.7	-42	177.1	179.9	61.5	0	0	0	111.6	Q213 G214 P215 G220 L221	Q213-L217 WeakPolarHBondContact O-CB 3.4Å; Q213-L217 PolarHBondContact O-N 2.91Å; G214-L217 PolarHBondContact O-N 3.28Å; P215-L217 PolarHBondContact O-N 3.31Å; L217-G220 PolarHBondContact O-N 3.2Å; L217-L221 HydrophobicContact CD1-CD1 4.21Å; L217-L221 HydrophobicContact CD1-CG 4.22Å; L217-L221 HydrophobicContact CG-CD1 4.05Å; L217-L221 HydrophobicContact CG-CG 4.48Å; L217-L221 WeakPolarHBondContact O-CB 3.29Å; L217-L221 VanDerWaalsContact O-CG 3.24Å; L217-L221 WeakPolarHBondContact O-CG 3.46Å; L217-L221 PolarHBondContact O-N 2.83Å
218	S	86.8	Confident	76.8	Confident	53 Å²	53	80.9 Å²	80.9	37%	0.371	47%	0.469	S	S	.	.	H	α-helix	trans	-66.1	-45.1	179.7	66.6	0	0	0	0	111.7	G214 P215 L221 W222	G214-S218 WeakPolarHBondContact O-CB 3.11Å; G214-S218 PolarHBondContact O-N 3.44Å; G214-S218 PolarHBondContact O-OG 3.11Å; P215-S218 PolarHBondContact O-N 3.21Å; P215-S218 PolarHBondContact O-OG 3.31Å; S218-L221 PolarHBondContact O-N 2.98Å; S218-W222 PolarHBondContact O-N 3.45Å
219	V	89.3	Confident	79.2	Confident	8 Å²	8	73.8 Å²	73.8	5%	0.048	44%	0.442	C	S	.	.	H	α-helix	trans	-57.3	-51	173.4	169.2	0	0	0	0	110.5	I189 A192 L193 P215 L221 W222 V223 P421	I189-V219 HydrophobicContact CG2-CG1 4.34Å; A192-V219 HydrophobicContact CB-CG1 4.24Å; A192-V219 HydrophobicContact CB-CG2 3.92Å; A192-V219 VanDerWaalsContact O-CG2 3.26Å; A192-V219 WeakPolarHBondContact O-CG2 3.35Å; L193-V219 HydrophobicContact CD2-CB 3.86Å; L193-V219 HydrophobicContact CD2-CG1 3.96Å; L193-V219 HydrophobicContact CD2-CG2 3.86Å; L193-V219 HydrophobicContact CG-CB 4.45Å; L193-V219 HydrophobicContact CG-CG1 4.06Å; L193-V219 HydrophobicContact CG-CG2 4.31Å; P215-V219 WeakPolarHBondContact O-CB 3.17Å; P215-V219 VanDerWaalsContact O-CG2 3.29Å; P215-V219 WeakPolarHBondContact O-CG2 3.49Å; P215-V219 PolarHBondContact O-N 3Å; V219-L221 VanDerWaalsContact C-N 3.31Å; V219-L221 PolarHBondContact O-N 2.89Å; V219-W222 PolarHBondContact O-N 3.48Å; V219-W222 VanDerWaalsContact O-N 3.08Å; V219-V223 HydrophobicContact CG1-CG2 4.47Å; V219-V223 WeakPolarHBondContact O-CG2 3.12Å; V219-V223 PolarHBondContact O-N 3.06Å; V219-P421 HydrophobicContact CG1-CB 4.03Å
220	G	92.5	Very high	81.8	Confident	39 Å²	39	69.9 Å²	69.9	40%	0.402	41%	0.413	S	S	.	.	H	α-helix	trans	-59.7	-37.2	178.6	0	0	0	0	0	113.8	I216 L217 L224	I216-G220 PolarHBondContact O-N 2.81Å; L217-G220 PolarHBondContact O-N 3.2Å; G220-L224 WeakPolarHBondContact O-CB 3.32Å; G220-L224 PolarHBondContact O-N 2.96Å
221	L	93	Very high	84.2	Confident	101 Å²	101	64.5 Å²	64.5	53%	0.529	39%	0.39	S	S	.	.	H	α-helix	trans	-67.3	-36.4	174.6	-74.7	171	0	0	0	112.5	L217 S218 V219 S225	L217-L221 HydrophobicContact CD1-CD1 4.21Å; L217-L221 HydrophobicContact CD1-CG 4.22Å; L217-L221 HydrophobicContact CG-CD1 4.05Å; L217-L221 HydrophobicContact CG-CG 4.48Å; L217-L221 WeakPolarHBondContact O-CB 3.29Å; L217-L221 VanDerWaalsContact O-CG 3.24Å; L217-L221 WeakPolarHBondContact O-CG 3.46Å; L217-L221 PolarHBondContact O-N 2.83Å; S218-L221 PolarHBondContact O-N 2.98Å; V219-L221 VanDerWaalsContact C-N 3.31Å; V219-L221 PolarHBondContact O-N 2.89Å; L221-S225 WeakPolarHBondContact O-CB 3.42Å; L221-S225 PolarHBondContact O-N 2.67Å
222	W	92.3	Very high	86.4	Confident	100 Å²	100	63.9 Å²	63.9	38%	0.379	38%	0.382	S	S	.	.	H	α-helix	trans	-74.5	-36.6	176.3	-72.1	119.9	0	0	0	113	S218 V219 L224 S225 G226 W418 P421 F422	S218-W222 PolarHBondContact O-N 3.45Å; V219-W222 PolarHBondContact O-N 3.48Å; V219-W222 VanDerWaalsContact O-N 3.08Å; W222-L224 VanDerWaalsContact C-N 3.35Å; W222-S225 WeakPolarHBondContact O-CB 3.48Å; W222-S225 PolarHBondContact O-N 3.01Å; W222-G226 PolarHBondContact O-N 3.16Å; W222-W418 HydrophobicContact CB-CB 4.48Å; W222-W418 HydrophobicContact CD2-CB 3.38Å; W222-W418 HydrophobicContact CD2-CG 4.4Å; W222-W418 HydrophobicContact CE3-CB 3.88Å; W222-W418 HydrophobicContact CG-CB 3.63Å; W222-W418 HydrophobicContact CH2-CB 4.22Å; W222-W418 HydrophobicContact CH2-CG 4.34Å; W222-W418 HydrophobicContact CZ2-CB 3.76Å; W222-W418 HydrophobicContact CZ2-CG 4.19Å; W222-W418 HydrophobicContact CZ3-CB 4.27Å; W222-W418 HydrophobicContact CZ3-CE3 4.44Å; W222-P421 HydrophobicContact CB-CB 3.83Å; W222-P421 HydrophobicContact CB-CG 3.6Å; W222-P421 HydrophobicContact CG-CG 4.39Å; W222-F422 WeakPolarHBondContact O-CA 3.04Å
223	V	94.8	Very high	87.9	Confident	16 Å²	16	63.6 Å²	63.6	10%	0.097	37%	0.365	C	S	.	.	H	α-helix	trans	-58.2	-48	168.4	177.3	0	0	0	0	110.5	I189 V219 S225 G226 I227 P421 G425 I428	I189-V223 HydrophobicContact CD1-CG1 4.37Å; I189-V223 HydrophobicContact CD1-CG2 3.85Å; I189-V223 HydrophobicContact CG1-CG2 3.8Å; V219-V223 HydrophobicContact CG1-CG2 4.47Å; V219-V223 WeakPolarHBondContact O-CG2 3.12Å; V219-V223 PolarHBondContact O-N 3.06Å; V223-S225 VanDerWaalsContact C-N 3.3Å; V223-S225 PolarHBondContact O-N 2.86Å; V223-G226 PolarHBondContact O-N 3.29Å; V223-I227 HydrophobicContact CG1-CD1 4.12Å; V223-I227 WeakPolarHBondContact O-CG1 3.38Å; V223-I227 PolarHBondContact O-N 3.17Å; V223-P421 VanDerWaalsContact CA-O 3.24Å; V223-P421 WeakPolarHBondContact CA-O 3.14Å; V223-P421 HydrophobicContact CG2-CB 3.64Å; V223-P421 WeakPolarHBondContact CG2-O 3.34Å; V223-G425 WeakPolarHBondContact O-CA 3.27Å; V223-I428 HydrophobicContact CG1-CD1 4.04Å
224	L	95.7	Very high	89.3	Confident	97 Å²	97	56.6 Å²	56.6	51%	0.508	33%	0.332	S	S	.	.	H	α-helix	trans	-63	-36.9	176	-175.6	62.2	0	0	0	112	G220 W222 I227 V228	G220-L224 WeakPolarHBondContact O-CB 3.32Å; G220-L224 PolarHBondContact O-N 2.96Å; W222-L224 VanDerWaalsContact C-N 3.35Å; L224-I227 PolarHBondContact O-N 3.47Å; L224-V228 HydrophobicContact CD1-CG2 4.3Å; L224-V228 HydrophobicContact CG-CG2 4.41Å; L224-V228 WeakPolarHBondContact O-CB 3.49Å; L224-V228 VanDerWaalsContact O-CG2 3.26Å; L224-V228 WeakPolarHBondContact O-CG2 3.35Å; L224-V228 PolarHBondContact O-N 2.98Å
225	S	93.8	Very high	90.2	Very high	46 Å²	46	61.8 Å²	61.8	32%	0.322	35%	0.345	S	S	.	.	H	α-helix	trans	-61.6	-43.3	174.9	-169	0	0	0	0	111.9	L221 W222 V223 V228 A229	L221-S225 WeakPolarHBondContact O-CB 3.42Å; L221-S225 PolarHBondContact O-N 2.67Å; W222-S225 WeakPolarHBondContact O-CB 3.48Å; W222-S225 PolarHBondContact O-N 3.01Å; V223-S225 VanDerWaalsContact C-N 3.3Å; V223-S225 PolarHBondContact O-N 2.86Å; S225-V228 PolarHBondContact O-N 3Å; S225-A229 VanDerWaalsContact O-CB 3.29Å; S225-A229 WeakPolarHBondContact O-CB 3.21Å; S225-A229 PolarHBondContact O-N 3.18Å
226	G	92.5	Very high	90.7	Very high	0 Å²	0	65.5 Å²	65.5	0%	0	36%	0.355	C	S	.	.	H	α-helix	trans	-59.3	-51.9	173.3	0	0	0	0	0	112.4	W222 V223 V228 A229 F230 F422	W222-G226 PolarHBondContact O-N 3.16Å; V223-G226 PolarHBondContact O-N 3.29Å; G226-V228 VanDerWaalsContact C-N 3.31Å; G226-V228 PolarHBondContact O-N 3.05Å; G226-A229 PolarHBondContact O-N 3.47Å; G226-F230 WeakPolarHBondContact O-CD2 3.37Å; G226-F230 PolarHBondContact O-N 2.74Å; G226-F422 WeakPolarHBondContact CA-O 3.45Å
227	I	95.3	Very high	90.4	Very high	48 Å²	48	61.9 Å²	61.9	25%	0.246	34%	0.338	C	S	.	.	H	α-helix	trans	-55	-46.2	176.4	-67.3	170	0	0	0	111	V223 L224 L231 G425 I428 Y429	V223-I227 HydrophobicContact CG1-CD1 4.12Å; V223-I227 WeakPolarHBondContact O-CG1 3.38Å; V223-I227 PolarHBondContact O-N 3.17Å; L224-I227 PolarHBondContact O-N 3.47Å; I227-L231 WeakPolarHBondContact O-CB 3.24Å; I227-L231 PolarHBondContact O-N 3.29Å; I227-G425 VanDerWaalsContact CG1-O 3.22Å; I227-G425 WeakPolarHBondContact CG1-O 3.3Å; I227-I428 HydrophobicContact CD1-CG2 4.18Å; I227-Y429 HydrophobicContact CG2-CD2 4.16Å
228	V	95.4	Very high	90.2	Very high	73 Å²	73	62.9 Å²	62.9	44%	0.442	33%	0.334	S	S	.	.	H	α-helix	trans	-68.9	-39.7	-179.9	170.3	0	0	0	0	111.8	L224 S225 G226 L231 V232	L224-V228 HydrophobicContact CD1-CG2 4.3Å; L224-V228 HydrophobicContact CG-CG2 4.41Å; L224-V228 WeakPolarHBondContact O-CB 3.49Å; L224-V228 VanDerWaalsContact O-CG2 3.26Å; L224-V228 WeakPolarHBondContact O-CG2 3.35Å; L224-V228 PolarHBondContact O-N 2.98Å; S225-V228 PolarHBondContact O-N 3Å; G226-V228 VanDerWaalsContact C-N 3.31Å; G226-V228 PolarHBondContact O-N 3.05Å; V228-L231 PolarHBondContact O-N 3.38Å; V228-V232 HydrophobicContact CG1-CG2 4.37Å; V228-V232 WeakPolarHBondContact O-CB 3.44Å; V228-V232 VanDerWaalsContact O-CG2 3.29Å; V228-V232 WeakPolarHBondContact O-CG2 3.47Å; V228-V232 PolarHBondContact O-N 2.93Å
229	A	90.9	Very high	90.1	Very high	32 Å²	32	67.5 Å²	67.5	26%	0.264	35%	0.349	S	S	.	.	H	α-helix	trans	-62	-46.5	177.1	0	0	0	0	0	111.2	S225 G226 L231 V232 V233 F422	S225-A229 VanDerWaalsContact O-CB 3.29Å; S225-A229 WeakPolarHBondContact O-CB 3.21Å; S225-A229 PolarHBondContact O-N 3.18Å; G226-A229 PolarHBondContact O-N 3.47Å; A229-L231 PolarHBondContact O-N 3.05Å; A229-V232 PolarHBondContact O-N 3.38Å; A229-V233 WeakPolarHBondContact O-CG2 3.34Å; A229-V233 PolarHBondContact O-N 2.92Å; A229-F422 HydrophobicContact CB-CE2 3.79Å; A229-F422 HydrophobicContact CB-CZ 3.7Å
230	F	91	Very high	89.8	Confident	16 Å²	16	71.3 Å²	71.3	7%	0.07	37%	0.372	C	S	.	.	H	α-helix	trans	-64	-40.2	176.9	-85.2	-111.3	0	0	0	112.1	G226 V232 V233 E234 L321 A324 A325 Y429 V430	G226-F230 WeakPolarHBondContact O-CD2 3.37Å; G226-F230 PolarHBondContact O-N 2.74Å; F230-V232 PolarHBondContact O-N 3.16Å; F230-V233 PolarHBondContact O-N 3.16Å; F230-E234 WeakPolarHBondContact O-CB 3.46Å; F230-E234 PolarHBondContact O-N 3.14Å; F230-L321 HydrophobicContact CD1-CB 4.4Å; F230-L321 HydrophobicContact CD1-CD2 4.18Å; F230-L321 WeakPolarHBondContact CE1-O 3.46Å; F230-A324 HydrophobicContact CE1-CB 4.37Å; F230-A324 HydrophobicContact CZ-CB 4.31Å; F230-A325 HydrophobicContact CE1-CB 3.69Å; F230-A325 HydrophobicContact CZ-CB 3.89Å; F230-Y429 HydrophobicContact CB-CD1 3.64Å; F230-Y429 HydrophobicContact CB-CD2 4.23Å; F230-Y429 HydrophobicContact CB-CE1 4.26Å; F230-Y429 HydrophobicContact CB-CG 3.63Å; F230-Y429 HydrophobicContact CD1-CD1 4.42Å; F230-V430 HydrophobicContact CD1-CG2 4.16Å; F230-V430 HydrophobicContact CE1-CG2 4.12Å
231	L	92.8	Very high	89	Confident	76 Å²	76	73.4 Å²	73.4	40%	0.398	37%	0.37	S	S	.	.	H	α-helix	trans	-59.4	-44	171.7	-171	156.7	0	0	0	112.3	I227 V228 A229 E234 K235 Y429	I227-L231 WeakPolarHBondContact O-CB 3.24Å; I227-L231 PolarHBondContact O-N 3.29Å; V228-L231 PolarHBondContact O-N 3.38Å; A229-L231 PolarHBondContact O-N 3.05Å; L231-E234 PolarHBondContact O-N 3.35Å; L231-K235 WeakPolarHBondContact O-CB 3.32Å; L231-K235 PolarHBondContact O-N 2.75Å; L231-Y429 WeakPolarHBondContact CA-OH 3.41Å; L231-Y429 HydrophobicContact CB-CD2 4.43Å; L231-Y429 HydrophobicContact CB-CE2 3.62Å; L231-Y429 HydrophobicContact CD1-CE2 4.35Å; L231-Y429 HydrophobicContact CG-CE2 4.19Å
232	V	91.4	Very high	87.5	Confident	85 Å²	85	71.3 Å²	71.3	52%	0.515	37%	0.374	S	S	.	.	H	α-helix	trans	-66	-45.5	179.1	167.6	0	0	0	0	111	V228 A229 F230 K235 F236	V228-V232 HydrophobicContact CG1-CG2 4.37Å; V228-V232 WeakPolarHBondContact O-CB 3.44Å; V228-V232 VanDerWaalsContact O-CG2 3.29Å; V228-V232 WeakPolarHBondContact O-CG2 3.47Å; V228-V232 PolarHBondContact O-N 2.93Å; A229-V232 PolarHBondContact O-N 3.38Å; F230-V232 PolarHBondContact O-N 3.16Å; V232-K235 PolarHBondContact O-N 3.32Å; V232-F236 VanDerWaalsContact O-CB 3.28Å; V232-F236 WeakPolarHBondContact O-CB 3.38Å; V232-F236 PolarHBondContact O-N 3.02Å
233	V	85.1	Confident	85.5	Confident	71 Å²	71	69.5 Å²	69.5	43%	0.43	39%	0.386	S	S	.	.	H	α-helix	trans	-59.5	-48.9	175	171.9	0	0	0	0	110.2	A229 F230 K235 F236 V237 L321	A229-V233 WeakPolarHBondContact O-CG2 3.34Å; A229-V233 PolarHBondContact O-N 2.92Å; F230-V233 PolarHBondContact O-N 3.16Å; V233-K235 PolarHBondContact O-N 2.64Å; V233-F236 PolarHBondContact O-N 3.29Å; V233-V237 HydrophobicContact CG1-CG2 4.4Å; V233-V237 WeakPolarHBondContact O-CG2 3.35Å; V233-V237 PolarHBondContact O-N 2.92Å; V233-L321 HydrophobicContact CB-CD2 4.17Å; V233-L321 HydrophobicContact CG1-CD2 3.84Å
234	E	87.3	Confident	83.3	Confident	13 Å²	13	76.3 Å²	76.3	6%	0.061	42%	0.416	C	S	.	.	H	α-helix	trans	-59.9	-49.7	178.8	-178.2	158.3	-162	0	0	111.4	F230 L231 F236 V237 R238 V317 L321 Y429	F230-E234 WeakPolarHBondContact O-CB 3.46Å; F230-E234 PolarHBondContact O-N 3.14Å; L231-E234 PolarHBondContact O-N 3.35Å; E234-F236 VanDerWaalsContact C-N 3.28Å; E234-F236 PolarHBondContact O-N 3.41Å; E234-V237 PolarHBondContact O-N 3.43Å; E234-R238 VanDerWaalsContact CD-NE 3.28Å; E234-R238 HydrophobicContact CG-CG 4.05Å; E234-R238 VanDerWaalsContact CG-NE 3.33Å; E234-R238 WeakPolarHBondContact O-CB 3.43Å; E234-R238 VanDerWaalsContact O-CG 3.31Å; E234-R238 WeakPolarHBondContact O-CG 3.32Å; E234-R238 PolarHBondContact O-N 2.89Å; E234-R238 IonicContact OE1-CZ 3.15Å; E234-R238 IonicContact OE1-NE 2.81Å; E234-R238 PolarHBondContact OE1-NE 3.04Å; E234-R238 IonicContact OE1-NH2 2.74Å; E234-R238 PolarHBondContact OE1-NH2 3.14Å; E234-R238 IonicContact OE2-CZ 3.69Å; E234-R238 IonicContact OE2-NE 3.99Å; E234-R238 IonicContact OE2-NH2 2.87Å; E234-R238 PolarHBondContact OE2-NH2 3.34Å; E234-V317 HydrophobicContact CB-CG1 4.39Å; E234-V317 HydrophobicContact CG-CG1 3.8Å; E234-L321 HydrophobicContact CB-CD1 3.65Å; E234-L321 HydrophobicContact CB-CD2 4Å; E234-L321 HydrophobicContact CB-CG 4.37Å; E234-L321 HydrophobicContact CG-CD1 3.82Å; E234-Y429 HydrophobicContact CB-CE1 4.38Å; E234-Y429 WeakPolarHBondContact OE2-CE1 3.27Å; E234-Y429 PolarHBondContact OE2-OH 3.42Å
235	K	87.3	Confident	80.7	Confident	145 Å²	145	74.9 Å²	74.9	63%	0.63	43%	0.425	S	S	*	.	H	α-helix	trans	-60.7	-38.7	-179.6	-172.8	173.3	-178	176.8	0	111.6	L231 V232 V233 H239	L231-K235 WeakPolarHBondContact O-CB 3.32Å; L231-K235 PolarHBondContact O-N 2.75Å; V232-K235 PolarHBondContact O-N 3.32Å; V233-K235 PolarHBondContact O-N 2.64Å; K235-H239 VanDerWaalsContact O-CB 3.3Å; K235-H239 WeakPolarHBondContact O-CB 3.33Å; K235-H239 PolarHBondContact O-N 3.36Å
236	F	86	Confident	78.2	Confident	136 Å²	136	79.8 Å²	79.8	60%	0.596	44%	0.443	S	S	*	.	H	α-helix	trans	-65.4	-49.7	174.9	179.9	-99.8	0	0	0	111.8	V232 V233 E234 R238 H239 V240	V232-F236 VanDerWaalsContact O-CB 3.28Å; V232-F236 WeakPolarHBondContact O-CB 3.38Å; V232-F236 PolarHBondContact O-N 3.02Å; V233-F236 PolarHBondContact O-N 3.29Å; E234-F236 VanDerWaalsContact C-N 3.28Å; E234-F236 PolarHBondContact O-N 3.41Å; F236-R238 PolarHBondContact O-N 2.81Å; F236-H239 WeakPolarHBondContact O-CB 3.33Å; F236-H239 PolarHBondContact O-N 2.91Å; F236-H239 VanDerWaalsContact O-N 3.1Å; F236-V240 HydrophobicContact CD1-CG2 4.34Å; F236-V240 HydrophobicContact CE1-CG2 3.93Å; F236-V240 HydrophobicContact CE2-CG2 4.17Å; F236-V240 HydrophobicContact CZ-CG2 3.84Å; F236-V240 WeakPolarHBondContact O-CG2 3.38Å; F236-V240 PolarHBondContact O-N 3.49Å
237	V	79.6	Confident	75.7	Confident	33 Å²	33	85.3 Å²	85.3	20%	0.2	48%	0.481	C	S	.	.	H	α-helix	trans	-64.6	-41.1	179.3	178	0	0	0	0	111.3	V233 E234 H239 V240 K241 V317	V233-V237 HydrophobicContact CG1-CG2 4.4Å; V233-V237 WeakPolarHBondContact O-CG2 3.35Å; V233-V237 PolarHBondContact O-N 2.92Å; E234-V237 PolarHBondContact O-N 3.43Å; V237-H239 VanDerWaalsContact C-N 3.3Å; V237-H239 PolarHBondContact O-N 3.32Å; V237-V240 PolarHBondContact O-N 3.28Å; V237-K241 HydrophobicContact CG1-CD 4.34Å; V237-K241 HydrophobicContact CG1-CG 4.42Å; V237-K241 WeakPolarHBondContact O-CB 3.08Å; V237-K241 PolarHBondContact O-N 2.81Å; V237-V317 HydrophobicContact CB-CG1 3.72Å; V237-V317 HydrophobicContact CB-CG2 4.46Å; V237-V317 HydrophobicContact CG1-CB 4.31Å; V237-V317 HydrophobicContact CG1-CG1 3.71Å; V237-V317 HydrophobicContact CG1-CG2 3.81Å
238	R	82.4	Confident	73.4	Confident	132 Å²	132	91.3 Å²	91.3	50%	0.498	51%	0.508	S	S	.	.	H	α-helix	trans	-60.2	-37.9	171.8	-71.5	-174.8	-162.9	162.9	5	111.8	E234 F236 G242 V317	E234-R238 VanDerWaalsContact CD-NE 3.28Å; E234-R238 HydrophobicContact CG-CG 4.05Å; E234-R238 VanDerWaalsContact CG-NE 3.33Å; E234-R238 WeakPolarHBondContact O-CB 3.43Å; E234-R238 VanDerWaalsContact O-CG 3.31Å; E234-R238 WeakPolarHBondContact O-CG 3.32Å; E234-R238 PolarHBondContact O-N 2.89Å; E234-R238 IonicContact OE1-CZ 3.15Å; E234-R238 IonicContact OE1-NE 2.81Å; E234-R238 PolarHBondContact OE1-NE 3.04Å; E234-R238 IonicContact OE1-NH2 2.74Å; E234-R238 PolarHBondContact OE1-NH2 3.14Å; E234-R238 IonicContact OE2-CZ 3.69Å; E234-R238 IonicContact OE2-NE 3.99Å; E234-R238 IonicContact OE2-NH2 2.87Å; E234-R238 PolarHBondContact OE2-NH2 3.34Å; F236-R238 PolarHBondContact O-N 2.81Å; R238-G242 VanDerWaalsContact O-CA 3.3Å; R238-G242 WeakPolarHBondContact O-CA 3.41Å; R238-G242 PolarHBondContact O-N 3.09Å; R238-V317 HydrophobicContact CG-CG2 4.06Å
239	H	84.5	Confident	70.7	Confident	150 Å²	150	91 Å²	91	69%	0.694	52%	0.519	S	S	*	.	H	α-helix	trans	-68.6	-44.7	177.1	-173.4	68.3	0	0	0	112	K235 F236 V237 G243	K235-H239 VanDerWaalsContact O-CB 3.3Å; K235-H239 WeakPolarHBondContact O-CB 3.33Å; K235-H239 PolarHBondContact O-N 3.36Å; F236-H239 WeakPolarHBondContact O-CB 3.33Å; F236-H239 PolarHBondContact O-N 2.91Å; F236-H239 VanDerWaalsContact O-N 3.1Å; V237-H239 VanDerWaalsContact C-N 3.3Å; V237-H239 PolarHBondContact O-N 3.32Å; H239-G243 PolarHBondContact O-N 2.87Å
240	V	82.6	Confident	68.6	Low	89 Å²	89	97.4 Å²	97.4	54%	0.539	54%	0.543	S	S	.	.	H	α-helix	trans	-65.7	-45.2	178.2	174.1	0	0	0	0	111.7	F236 V237	F236-V240 HydrophobicContact CD1-CG2 4.34Å; F236-V240 HydrophobicContact CE1-CG2 3.93Å; F236-V240 HydrophobicContact CE2-CG2 4.17Å; F236-V240 HydrophobicContact CZ-CG2 3.84Å; F236-V240 WeakPolarHBondContact O-CG2 3.38Å; F236-V240 PolarHBondContact O-N 3.49Å; V237-V240 PolarHBondContact O-N 3.28Å
241	K	75.4	Confident	66.1	Low	82 Å²	82	100.3 Å²	100.3	36%	0.357	58%	0.578	S	S	.	*	H	α-helix	trans	-74.1	-34	177.1	-71.3	-165.7	170.2	-157.3	0	112.9	V237 G243 D314 L315	V237-K241 HydrophobicContact CG1-CD 4.34Å; V237-K241 HydrophobicContact CG1-CG 4.42Å; V237-K241 WeakPolarHBondContact O-CB 3.08Å; V237-K241 PolarHBondContact O-N 2.81Å; K241-G243 PolarHBondContact O-N 2.87Å; K241-D314 IonicContact NZ-OD1 3.22Å; K241-D314 PolarHBondContact NZ-OD1 2.91Å; K241-L315 PolarHBondContact NZ-O 2.74Å
242	G	60.5	Low	64.1	Low	58 Å²	58	102.9 Å²	102.9	60%	0.598	59%	0.588	S	S	*	*	H	α-helix	trans	-69.5	-10.6	-179.6	0	0	0	0	0	115.2	R238 H244	R238-G242 VanDerWaalsContact O-CA 3.3Å; R238-G242 WeakPolarHBondContact O-CA 3.41Å; R238-G242 PolarHBondContact O-N 3.09Å; G242-H244 PolarHBondContact O-N 2.99Å
243	G	51.7	Low	61.8	Low	61 Å²	61	103.9 Å²	103.9	63%	0.629	61%	0.605	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.6	-6.9	178	0	0	0	0	0	116	H239 K241	H239-G243 PolarHBondContact O-N 2.87Å; K241-G243 PolarHBondContact O-N 2.87Å
244	H	47.1	Very low	60.2	Low	159 Å²	159	107 Å²	107	74%	0.736	62%	0.615	S	S	*	*	T	Hydrogen-bonded Turn	trans	-116.7	40.1	-177.3	-82.6	86.3	0	0	0	113.9	G242 H246	G242-H244 PolarHBondContact O-N 2.99Å; H244-H246 PolarHBondContact O-N 3.24Å
245	G	42.3	Very low	58.4	Low	68 Å²	68	111.8 Å²	111.8	70%	0.701	65%	0.649	S	S	*	*			trans	-85	68.8	171.5	0	0	0	0	0	114	S247	G245-S247 PolarHBondContact O-N 2.74Å; G245-S247 VanDerWaalsContact O-N 3.09Å
246	H	42	Very low	56.4	Low	149 Å²	149	113.1 Å²	113.1	69%	0.69	66%	0.657	S	S	*	*			trans	-73.8	96.1	172.3	-77.4	123.5	0	0	0	111.6	H244 H248	H244-H246 PolarHBondContact O-N 3.24Å; H246-H248 VanDerWaalsContact C-N 3.34Å; H246-H248 PolarHBondContact O-N 2.77Å
247	S	38.7	Very low	54.5	Low	115 Å²	115	112.9 Å²	112.9	80%	0.804	67%	0.667	S	S	*	*			trans	-75.6	79.2	169.8	49.3	0	0	0	0	111.8	G245 G249	G245-S247 PolarHBondContact O-N 2.74Å; G245-S247 VanDerWaalsContact O-N 3.09Å; S247-G249 PolarHBondContact O-N 2.84Å
248	H	46.5	Very low	52.8	Low	174 Å²	174	123.2 Å²	123.2	81%	0.806	70%	0.703	S	S	*	*			trans	-74.2	69.4	169	-82.4	-70.6	0	0	0	112	H246 H250	H246-H248 VanDerWaalsContact C-N 3.34Å; H246-H248 PolarHBondContact O-N 2.77Å; H248-H250 PolarHBondContact O-N 3.23Å
249	G	39.3	Very low	50.6	Low	67 Å²	67	120.8 Å²	120.8	69%	0.691	72%	0.718	S	S	*	*			trans	-95.8	67.9	174.4	0	0	0	0	0	113.1	S247	S247-G249 PolarHBondContact O-N 2.84Å
250	H	46.9	Very low	48.7	Very low	166 Å²	166	117.9 Å²	117.9	77%	0.769	72%	0.715	S	S	*	*			trans	-144.8	94.7	163	-99.5	-50.3	0	0	0	111.8	H248 H252	H248-H250 PolarHBondContact O-N 3.23Å; H250-H252 AromaticContact ND1-CD2 3.92Å; H250-H252 PolarHBondContact O-N 3.09Å
251	G	39.6	Very low	46.9	Very low	77 Å²	77	122.4 Å²	122.4	79%	0.794	73%	0.73	S	S	*	*			trans	-81.5	106	165.2	0	0	0	0	0	110.7
252	H	50.1	Low	45.3	Very low	131 Å²	131	121.7 Å²	121.7	61%	0.606	75%	0.745	S	S	*	*			trans	-136.5	82.6	166.4	-80.9	-56.7	0	0	0	110.7	H250 H254	H250-H252 AromaticContact ND1-CD2 3.92Å; H250-H252 PolarHBondContact O-N 3.09Å; H252-H254 AromaticContact CG-NE2 3.95Å; H252-H254 PolarHBondContact O-N 3.24Å
253	A	43.4	Very low	44.3	Very low	105 Å²	105	128.8 Å²	128.8	87%	0.868	76%	0.763	S	S	*	*			trans	-80.2	95.2	167.9	0	0	0	0	0	109.8	S255	A253-S255 PolarHBondContact O-N 3.01Å
254	H	50.6	Low	43.7	Very low	138 Å²	138	129.4 Å²	129.4	64%	0.639	77%	0.769	S	S	*	*			trans	-91	91.2	172.8	-65	-66	0	0	0	110.8	H252 H256	H252-H254 AromaticContact CG-NE2 3.95Å; H252-H254 PolarHBondContact O-N 3.24Å; H254-H256 PolarHBondContact O-N 3.07Å
255	S	49.2	Very low	43.3	Very low	112 Å²	112	132.6 Å²	132.6	78%	0.783	77%	0.774	S	S	*	*			trans	-78.2	99.2	170.5	60.1	0	0	0	0	110.7	A253 T257	A253-S255 PolarHBondContact O-N 3.01Å; S255-T257 PolarHBondContact O-N 3.4Å
256	H	45.1	Very low	43	Very low	173 Å²	173	137.6 Å²	137.6	80%	0.801	78%	0.78	S	S	*	*			trans	-79	114.4	170.9	-67.1	-93.1	0	0	0	111	H254	H254-H256 PolarHBondContact O-N 3.07Å
257	T	46.8	Very low	42.9	Very low	132 Å²	132	136.9 Å²	136.9	81%	0.81	78%	0.776	S	S	*	*			trans	-141.8	98.2	162.8	8.6	0	0	0	0	111.8	S255	S255-T257 PolarHBondContact O-N 3.4Å
258	R	43.6	Very low	42.8	Very low	250 Å²	250	141.4 Å²	141.4	94%	0.943	78%	0.776	S	S	*	*			trans	-1.5	121.4	161	-72	172.2	158.4	166.3	-7.2	117.4
259	G	37	Very low	42.3	Very low	80 Å²	80	137.4 Å²	137.4	83%	0.825	77%	0.768	S	S	*	*			trans	-79.7	141.2	151.1	0	0	0	0	0	111.6
260	S	43.6	Very low	42.1	Very low	90 Å²	90	139.6 Å²	139.6	63%	0.629	77%	0.768	S	S	*	*			trans	-169	142.5	146.8	-165.1	0	0	0	0	110.2
261	H	44.7	Very low	41.6	Very low	184 Å²	184	139.9 Å²	139.9	85%	0.852	77%	0.767	S	S	*	*			trans	66.6	143.3	175.9	-42	-71	0	0	0	116.2
262	G	41.6	Very low	41.5	Very low	66 Å²	66	143.1 Å²	143.1	68%	0.68	76%	0.761	S	S	*	*			cis	150.2	117.2	-6.6	0	0	0	0	0	112.6
263	H	41.4	Very low	40.7	Very low	208 Å²	208	145.5 Å²	145.5	96%	0.963	77%	0.77	S	S	*	*			trans	61	128.2	168.5	-85.4	-93.3	0	0	0	120.6
264	G	38.9	Very low	40.2	Very low	73 Å²	73	147.1 Å²	147.1	75%	0.753	76%	0.759	S	S	*	*				132.9	90.3	121.1	0	0	0	0	0	120.7
265	R	37.6	Very low	39.4	Very low	227 Å²	227	145.5 Å²	145.5	86%	0.857	76%	0.764	S	S	*	*			trans	71.2	89	133.6	-159.6	178.3	-171.4	-176.3	1.6	121.3
266	Q	36.6	Very low	38.7	Very low	173 Å²	173	144 Å²	144	81%	0.808	75%	0.753	S	S	*	*				41.9	146.7	105.3	-145.9	177.3	10	0	0	122.4
267	E	39.9	Very low	38.2	Very low	133 Å²	133	143.4 Å²	143.4	62%	0.621	75%	0.75	S	S	*	*			trans	86.1	140	165	-64.3	-154.9	117.5	0	0	117.9
268	R	35.6	Very low	37.7	Very low	210 Å²	210	144.9 Å²	144.9	79%	0.792	75%	0.748	S	S	*	*			cis	-162.1	-179.2	-17.6	-146.3	169.4	-178.5	161.2	-9.6	110.1
269	S	35.8	Very low	37.2	Very low	91 Å²	91	141.1 Å²	141.1	64%	0.636	74%	0.741	S	S	*	*			trans	-50.8	169.8	179.7	64	0	0	0	0	116.3
270	T	36.3	Very low	37.1	Very low	113 Å²	113	144.9 Å²	144.9	69%	0.693	74%	0.737	S	S	*	*			cis	-174.2	152.8	44.6	-18.1	0	0	0	0	111.8
271	K	35.2	Very low	36.6	Very low	172 Å²	172	148.9 Å²	148.9	75%	0.748	74%	0.743	S	S	*	*			trans	45.3	135.6	138.1	-100.6	-178.1	153.5	-141	0	119.9
272	E	38	Very low	36	Very low	144 Å²	144	147.8 Å²	147.8	67%	0.673	74%	0.739	S	S	*	*			cis	-164.8	147.5	47	-103.9	156.5	-174	0	0	110.1
273	K	34.2	Very low	35.6	Very low	181 Å²	181	149.8 Å²	149.8	79%	0.787	74%	0.738	S	S	*	*				42.6	143.1	107.6	-80.1	-167.7	165.8	-138.8	0	117.2
274	Q	33.2	Very low	35.4	Very low	139 Å²	139	151.5 Å²	151.5	65%	0.65	74%	0.736	S	S	*	*			cis	-177.7	152.4	-3.1	173.3	178.8	-25.9	0	0	108.7
275	S	33.7	Very low	35.4	Very low	105 Å²	105	151.7 Å²	151.7	73%	0.734	74%	0.738	S	S	*	*			trans	58.8	159.6	164.2	45.5	0	0	0	0	119.1
276	S	32.8	Very low	35.3	Very low	79 Å²	79	147.4 Å²	147.4	55%	0.552	74%	0.737	S	S	*	*			cis	-169.6	162.8	-21	49.8	0	0	0	0	108.2
277	E	35.9	Very low	35.6	Very low	161 Å²	161	148.8 Å²	148.8	75%	0.752	74%	0.743	S	S	*	*			trans	58.9	159.9	160.7	-66.5	125	-173.3	0	0	117.7
278	E	35.9	Very low	35.5	Very low	164 Å²	164	150.6 Å²	150.6	77%	0.766	75%	0.749	S	S	*	*			cis	-157.2	155.9	-17.8	-113	168.3	177.5	0	0	108.9
279	E	33.7	Very low	35.9	Very low	170 Å²	170	152.8 Å²	152.8	79%	0.794	76%	0.757	S	S	*	*			trans	49.1	148.7	150.3	-74	-162.6	135.8	0	0	127.8
280	E	34.4	Very low	36	Very low	159 Å²	159	159.4 Å²	159.4	74%	0.743	77%	0.768	S	S	*	*			trans	71.5	113.5	153.8	-69.5	-156.1	123.2	0	0	125.7
281	K	32.9	Very low	36.1	Very low	174 Å²	174	158.1 Å²	158.1	76%	0.757	78%	0.777	S	S	*	*				18	138	125.5	-72.6	176.9	175.4	171	0	117.9
282	E	32.6	Very low	36.3	Very low	161 Å²	161	154 Å²	154	75%	0.752	78%	0.783	S	S	*	*			cis	-179.2	169.1	47.9	-152.2	-178.3	-145.8	0	0	112.4
283	T	33.3	Very low	36.2	Very low	108 Å²	108	152.1 Å²	152.1	66%	0.663	79%	0.787	S	S	*	*			trans	91.7	147.5	156.4	76.9	0	0	0	0	122
284	R	36.6	Very low	36.5	Very low	245 Å²	245	150.4 Å²	150.4	93%	0.925	79%	0.791	S	S	*	*			trans	82	131.3	171.1	-54.7	-180	175	-162.9	-2.7	116.1
285	G	39.5	Very low	37	Very low	77 Å²	77	149.9 Å²	149.9	79%	0.794	80%	0.798	S	S	*	*			cis	-167.3	161.6	-0.6	0	0	0	0	0	113.8
286	V	35	Very low	37.5	Very low	137 Å²	137	149.9 Å²	149.9	83%	0.83	80%	0.795	S	S	*	*			trans	-86	140.7	-171.7	172.3	0	0	0	0	112.4	K288	V286-K288 HydrophobicContact CG1-CB 4.39Å
287	Q	43.5	Very low	37.9	Very low	202 Å²	202	155.9 Å²	155.9	94%	0.944	81%	0.811	S	S	*	*			trans	-133.4	140.7	152.1	-113.3	-178.4	9.2	0	0	112.2
288	K	37	Very low	38.1	Very low	171 Å²	171	156 Å²	156	74%	0.743	82%	0.817	S	S	*	*			trans	-142.2	130.8	-163.4	171.1	-174.5	-175.7	175.1	0	108.7	V286	V286-K288 HydrophobicContact CG1-CB 4.39Å
289	R	44.1	Very low	38.7	Very low	255 Å²	255	150.9 Å²	150.9	96%	0.962	81%	0.808	S	S	*	*			trans	-146.7	146	160.3	-110.8	170.5	-176.7	-168	-2	111.8
290	R	39.1	Very low	39.2	Very low	230 Å²	230	148.9 Å²	148.9	87%	0.868	81%	0.81	S	S	*	*			trans	-106.5	150.7	-166.3	-81.1	169.9	143.6	179.8	-7.8	111.7
291	G	36.7	Very low	39.6	Very low	86 Å²	86	148.1 Å²	148.1	89%	0.887	82%	0.816	S	S	*	*				101.3	130.3	118.6	0	0	0	0	0	118.5
292	G	40.1	Very low	40	Very low	85 Å²	85	149.5 Å²	149.5	88%	0.876	82%	0.816	S	S	*	*			trans	161.5	121.3	169.2	0	0	0	0	0	111
293	S	36.4	Very low	40.4	Very low	106 Å²	106	146.6 Å²	146.6	74%	0.741	81%	0.812	S	S	*	*			trans	-111.2	142.1	-174.6	176.9	0	0	0	0	111.8
294	T	40.1	Very low	40.7	Very low	144 Å²	144	150.5 Å²	150.5	88%	0.883	82%	0.823	S	S	*	*			trans	179.3	162.2	133.1	24.6	0	0	0	0	111.9
295	V	44.3	Very low	40.9	Very low	129 Å²	129	146.1 Å²	146.1	78%	0.782	82%	0.817	S	S	*	*			trans	-130.9	168.4	-158.2	177.1	0	0	0	0	108.6
296	P	42.6	Very low	40.9	Very low	105 Å²	105	146.6 Å²	146.6	68%	0.682	81%	0.814	S	S	*	*			cis	-117.1	-178	-36.1	35.7	-21.2	0	0	0	112.1
297	K	43.3	Very low	41.1	Very low	205 Å²	205	148.4 Å²	148.4	89%	0.891	81%	0.813	S	S	*	*			trans	-158.4	120	142.6	-126.6	173.2	-175.4	177.6	0	113.4
298	D	38.8	Very low	41	Very low	162 Å²	162	147.9 Å²	147.9	87%	0.866	81%	0.811	S	S	*	*			trans	-65.6	133.8	172	-58.5	-73.4	0	0	0	111.3
299	G	48.8	Very low	41	Very low	57 Å²	57	147.1 Å²	147.1	59%	0.588	81%	0.81	S	S	*	*			trans	-123.9	137.9	167.9	0	0	0	0	0	108.9	V301	G299-V301 PolarHBondContact O-N 3.42Å
300	P	44.4	Very low	40.5	Very low	128 Å²	128	144.9 Å²	144.9	83%	0.831	81%	0.807	S	S	*	*			trans	-69.7	123.1	-169.6	27.3	-34.2	0	0	0	111.4	R302	P300-R302 PolarHBondContact O-N 3.37Å
301	V	43.5	Very low	40.5	Very low	144 Å²	144	145 Å²	145	87%	0.873	81%	0.808	S	S	*	*			trans	-66.3	96.9	163.8	178.3	0	0	0	0	107.5	G299 P303	G299-V301 PolarHBondContact O-N 3.42Å; V301-P303 WeakPolarHBondContact O-CD 3.26Å
302	R	40.7	Very low	41.1	Very low	202 Å²	202	144.1 Å²	144.1	76%	0.762	80%	0.799	S	S	*	*			trans	-72.4	120.4	176.7	-163	-178.7	-155.9	-138.9	4.5	108.4	P300 Q304	P300-R302 PolarHBondContact O-N 3.37Å; R302-Q304 PolarHBondContact O-N 2.91Å
303	P	39.8	Very low	42.1	Very low	101 Å²	101	143.3 Å²	143.3	66%	0.656	77%	0.774	S	S	*	*			trans	-66.9	124.2	176.5	27.4	-32.8	0	0	0	109.2	V301 N305	V301-P303 WeakPolarHBondContact O-CD 3.26Å; P303-N305 PolarHBondContact O-N 2.86Å
304	Q	40.3	Very low	43.9	Very low	190 Å²	190	144.8 Å²	144.8	89%	0.888	77%	0.773	S	S	*	*	S	Bend	trans	-78.8	27.9	179.7	-67.6	-178.6	-20.3	0	0	112.8	R302	R302-Q304 PolarHBondContact O-N 2.91Å
305	N	40.3	Very low	45.9	Very low	152 Å²	152	138 Å²	138	81%	0.813	73%	0.732	S	S	*	*			trans	-116.3	58.4	-171.6	-64.4	8.4	0	0	0	110.8	P303	P303-N305 PolarHBondContact O-N 2.86Å
306	A	40.7	Very low	47.9	Very low	88 Å²	88	138.5 Å²	138.5	73%	0.727	72%	0.72	S	S	*	*	S	Bend	trans	-149.9	3.1	-179.8	0	0	0	0	0	115.7
307	E	39.2	Very low	49.9	Very low	175 Å²	175	134.5 Å²	134.5	82%	0.818	69%	0.693	S	S	*	*	S	Bend	trans	-107.4	4.5	-172.9	-64	-170	171.5	0	0	114.6
308	E	39.8	Very low	52	Low	190 Å²	190	125.8 Å²	125.8	89%	0.888	66%	0.658	S	S	*	*	S	Bend	trans	-82.8	-14.7	179.6	-76.5	-170.5	129.6	0	0	115.2	K310	E308-K310 PolarHBondContact O-N 3.18Å
309	E	37.3	Very low	54.4	Low	155 Å²	155	118 Å²	118	72%	0.724	62%	0.617	S	S	*	*	T	Hydrogen-bonded Turn	trans	-90	12.9	-163.9	-157.5	160.9	-150.3	0	0	115.8	R382	E309-R382 IonicContact OE1-NH1 3.69Å
310	K	34.2	Very low	56.4	Low	208 Å²	208	120.1 Å²	120.1	90%	0.904	61%	0.607	S	S	*	*	T	Hydrogen-bonded Turn	trans	-132.3	19	177.9	-83	-165.6	176.1	-176.4	0	116.6	E308 G312	E308-K310 PolarHBondContact O-N 3.18Å; K310-G312 PolarHBondContact O-N 3.09Å
311	R	38.4	Very low	58.5	Low	233 Å²	233	114 Å²	114	88%	0.879	57%	0.568	S	S	*	*	S	Bend	trans	-76.4	114.1	161.9	-126.1	175.4	178.2	177.6	-2.6	108.3	L313	R311-L313 PolarHBondContact O-N 2.88Å
312	G	49	Very low	60.8	Low	68 Å²	68	107.2 Å²	107.2	70%	0.701	53%	0.526	S	S	*	.			trans	-54.2	138.2	174.8	0	0	0	0	0	110.5	K310 D314	K310-G312 PolarHBondContact O-N 3.09Å; G312-D314 PolarHBondContact O-N 3.47Å
313	L	62.4	Low	63.2	Low	68 Å²	68	98.8 Å²	98.8	36%	0.356	50%	0.497	S	S	.	.			trans	-65	96	-177.4	-112.6	135.7	0	0	0	109.8	R311 L315 Y320 L383	R311-L313 PolarHBondContact O-N 2.88Å; L313-L315 HydrophobicContact CD2-CB 4.22Å; L313-L315 PolarHBondContact O-N 3.42Å; L313-Y320 PolarHBondContact O-OH 3.15Å; L313-L383 HydrophobicContact CD2-CD1 4Å
314	D	73.1	Confident	65.6	Low	136 Å²	136	96 Å²	96	73%	0.727	48%	0.482	S	S	*	.			trans	-81.5	60.2	173.6	-163.4	17.6	0	0	0	110.9	K241 G312	K241-D314 IonicContact NZ-OD1 3.22Å; K241-D314 PolarHBondContact NZ-OD1 2.91Å; G312-D314 PolarHBondContact O-N 3.47Å
315	L	82.2	Confident	67.9	Low	3 Å²	3	87.1 Å²	87.1	2%	0.016	44%	0.441	C	S	.	.			trans	-72.1	132.8	178.9	-174.8	61.8	0	0	0	109.4	K241 L313 Y320 L323 L370 S373 C375	K241-L315 PolarHBondContact NZ-O 2.74Å; L313-L315 HydrophobicContact CD2-CB 4.22Å; L313-L315 PolarHBondContact O-N 3.42Å; L315-Y320 HydrophobicContact CB-CD2 4.15Å; L315-Y320 HydrophobicContact CB-CE2 3.63Å; L315-Y320 HydrophobicContact CD2-CD1 4.4Å; L315-Y320 HydrophobicContact CD2-CD2 4.14Å; L315-Y320 HydrophobicContact CD2-CE1 4.43Å; L315-Y320 HydrophobicContact CD2-CE2 4.19Å; L315-Y320 HydrophobicContact CD2-CG 4.26Å; L315-Y320 HydrophobicContact CG-CD2 4.17Å; L315-Y320 HydrophobicContact CG-CE2 4.14Å; L315-Y320 WeakPolarHBondContact O-CE2 3.39Å; L315-L323 HydrophobicContact CD2-CD1 4.18Å; L315-L370 HydrophobicContact CD1-CD2 4.49Å; L315-L370 HydrophobicContact CD2-CD2 4.33Å; L315-S373 VanDerWaalsContact CD1-CB 3.48Å; L315-C375 VanDerWaalsContact CD1-SG 3.57Å
316	R	86	Confident	70.3	Confident	139 Å²	139	80 Å²	80	53%	0.525	40%	0.403	S	S	.	.			trans	-58.9	154.9	170.8	-68.7	-179.6	-174.3	167.8	0.6	110.4	S318 G319 Q372 S373	R316-S318 WeakPolarHBondContact CB-OG 3.29Å; R316-S318 PolarHBondContact O-N 3.27Å; R316-G319 PolarHBondContact O-N 2.77Å; R316-Q372 PolarHBondContact NH1-O 3.19Å; R316-S373 WeakPolarHBondContact CG-O 3.43Å; R316-S373 PolarHBondContact N-O 3.29Å
317	V	86.6	Confident	72.7	Confident	21 Å²	21	79.5 Å²	79.5	13%	0.127	39%	0.388	C	S	.	.	H	α-helix	trans	-60	-35.7	-175.3	-166.5	0	0	0	0	111.9	E234 V237 R238 G319 Y320 L321	E234-V317 HydrophobicContact CB-CG1 4.39Å; E234-V317 HydrophobicContact CG-CG1 3.8Å; V237-V317 HydrophobicContact CB-CG1 3.72Å; V237-V317 HydrophobicContact CB-CG2 4.46Å; V237-V317 HydrophobicContact CG1-CB 4.31Å; V237-V317 HydrophobicContact CG1-CG1 3.71Å; V237-V317 HydrophobicContact CG1-CG2 3.81Å; R238-V317 HydrophobicContact CG-CG2 4.06Å; V317-G319 VanDerWaalsContact C-N 3.28Å; V317-G319 PolarHBondContact O-N 3.24Å; V317-Y320 PolarHBondContact O-N 2.66Å; V317-Y320 VanDerWaalsContact O-N 3.09Å; V317-L321 HydrophobicContact CG1-CD1 4.19Å; V317-L321 HydrophobicContact CG1-CG 4.36Å; V317-L321 WeakPolarHBondContact O-CG 3.49Å; V317-L321 PolarHBondContact O-N 2.92Å
318	S	85.5	Confident	74.9	Confident	21 Å²	21	72.1 Å²	72.1	15%	0.147	36%	0.357	C	S	.	.	H	α-helix	trans	-45.6	-47.3	169.4	48.8	0	0	0	0	113.4	R316 Y320 L321 N322 S373	R316-S318 WeakPolarHBondContact CB-OG 3.29Å; R316-S318 PolarHBondContact O-N 3.27Å; S318-Y320 PolarHBondContact O-N 2.99Å; S318-L321 PolarHBondContact O-N 3.33Å; S318-N322 WeakPolarHBondContact O-CB 3.45Å; S318-N322 PolarHBondContact O-N 3.47Å; S318-S373 PolarHBondContact OG-OG 2.9Å
319	G	90.2	Very high	77.3	Confident	0 Å²	0	63.2 Å²	63.2	0%	0	32%	0.315	C	S	.	.	H	α-helix	trans	-70	-31.4	-178.3	0	0	0	0	0	113.6	R316 V317 L323 S373	R316-G319 PolarHBondContact O-N 2.77Å; V317-G319 VanDerWaalsContact C-N 3.28Å; V317-G319 PolarHBondContact O-N 3.24Å; G319-L323 WeakPolarHBondContact O-CG 3.49Å; G319-L323 PolarHBondContact O-N 3.01Å; G319-S373 WeakPolarHBondContact CA-OG 3.38Å; G319-S373 PolarHBondContact N-OG 3.38Å; G319-S373 VanDerWaalsContact N-OG 3.16Å
320	Y	90.2	Very high	79.8	Confident	100 Å²	100	55.9 Å²	55.9	39%	0.392	28%	0.281	S	S	.	.	H	α-helix	trans	-72	-38.9	173.1	-76.1	-75.8	0	0	0	112.4	L313 L315 V317 S318 N322 A324	L313-Y320 PolarHBondContact O-OH 3.15Å; L315-Y320 HydrophobicContact CB-CD2 4.15Å; L315-Y320 HydrophobicContact CB-CE2 3.63Å; L315-Y320 HydrophobicContact CD2-CD1 4.4Å; L315-Y320 HydrophobicContact CD2-CD2 4.14Å; L315-Y320 HydrophobicContact CD2-CE1 4.43Å; L315-Y320 HydrophobicContact CD2-CE2 4.19Å; L315-Y320 HydrophobicContact CD2-CG 4.26Å; L315-Y320 HydrophobicContact CG-CD2 4.17Å; L315-Y320 HydrophobicContact CG-CE2 4.14Å; L315-Y320 WeakPolarHBondContact O-CE2 3.39Å; V317-Y320 PolarHBondContact O-N 2.66Å; V317-Y320 VanDerWaalsContact O-N 3.09Å; S318-Y320 PolarHBondContact O-N 2.99Å; Y320-N322 VanDerWaalsContact C-N 3.32Å; Y320-A324 WeakPolarHBondContact O-CB 3.43Å; Y320-A324 PolarHBondContact O-N 3.47Å; Y320-A324 VanDerWaalsContact O-N 3.11Å
321	L	89.9	Confident	82.5	Confident	1 Å²	1	48.7 Å²	48.7	1%	0.005	25%	0.25	C	C	.	.	H	α-helix	trans	-65.5	-40.9	175.2	-63.3	164.1	0	0	0	110.4	F230 V233 E234 V317 S318 A324 A325 Y429 V430	F230-L321 HydrophobicContact CD1-CB 4.4Å; F230-L321 HydrophobicContact CD1-CD2 4.18Å; F230-L321 WeakPolarHBondContact CE1-O 3.46Å; V233-L321 HydrophobicContact CB-CD2 4.17Å; V233-L321 HydrophobicContact CG1-CD2 3.84Å; E234-L321 HydrophobicContact CB-CD1 3.65Å; E234-L321 HydrophobicContact CB-CD2 4Å; E234-L321 HydrophobicContact CB-CG 4.37Å; E234-L321 HydrophobicContact CG-CD1 3.82Å; V317-L321 HydrophobicContact CG1-CD1 4.19Å; V317-L321 HydrophobicContact CG1-CG 4.36Å; V317-L321 WeakPolarHBondContact O-CG 3.49Å; V317-L321 PolarHBondContact O-N 2.92Å; S318-L321 PolarHBondContact O-N 3.33Å; L321-A324 PolarHBondContact O-N 2.91Å; L321-A324 VanDerWaalsContact O-N 3.16Å; L321-A325 PolarHBondContact O-N 3.5Å; L321-Y429 HydrophobicContact CD1-CE1 4.21Å; L321-V430 HydrophobicContact CB-CG2 4.31Å
322	N	90.5	Very high	84.8	Confident	0 Å²	0	37.8 Å²	37.8	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-55.9	-54	175.6	-152.7	89.5	0	0	0	111.7	S318 Y320 A324 A325 D326 D366 I369 V430	S318-N322 WeakPolarHBondContact O-CB 3.45Å; S318-N322 PolarHBondContact O-N 3.47Å; Y320-N322 VanDerWaalsContact C-N 3.32Å; N322-A324 PolarHBondContact O-N 2.99Å; N322-A325 WeakPolarHBondContact O-CB 3.35Å; N322-A325 PolarHBondContact O-N 3.37Å; N322-D326 VanDerWaalsContact O-CB 3.29Å; N322-D326 WeakPolarHBondContact O-CB 3.38Å; N322-D326 PolarHBondContact O-N 3Å; N322-D366 VanDerWaalsContact ND2-CB 3.29Å; N322-D366 WeakPolarHBondContact ND2-CB 3.45Å; N322-D366 PolarHBondContact ND2-OD1 3.28Å; N322-D366 PolarHBondContact OD1-OD1 3.48Å; N322-I369 HydrophobicContact CB-CG2 3.88Å; N322-I369 WeakPolarHBondContact OD1-CD1 3.49Å; N322-I369 VanDerWaalsContact OD1-CG2 3.25Å; N322-I369 WeakPolarHBondContact OD1-CG2 3.1Å; N322-V430 WeakPolarHBondContact OD1-CG1 3.29Å
323	L	91.8	Very high	86.7	Confident	26 Å²	26	34.9 Å²	34.9	14%	0.136	18%	0.177	C	C	.	.	H	α-helix	trans	-61.1	-29.3	178	-68	167.9	0	0	0	113.4	L315 G319 L327 L370 L383 T387	L315-L323 HydrophobicContact CD2-CD1 4.18Å; G319-L323 WeakPolarHBondContact O-CG 3.49Å; G319-L323 PolarHBondContact O-N 3.01Å; L323-L327 WeakPolarHBondContact O-CB 3.46Å; L323-L327 PolarHBondContact O-N 3.49Å; L323-L370 HydrophobicContact CD1-CD2 3.98Å; L323-L370 HydrophobicContact CD2-CD1 4.06Å; L323-L370 HydrophobicContact CD2-CD2 4.12Å; L323-L370 HydrophobicContact CG-CD2 3.91Å; L323-L383 HydrophobicContact CD1-CB 4.04Å; L323-L383 HydrophobicContact CD1-CD1 4.27Å; L323-L383 HydrophobicContact CD1-CD2 4.15Å; L323-L383 HydrophobicContact CD1-CG 4.38Å; L323-L383 HydrophobicContact CD2-CB 3.82Å; L323-T387 HydrophobicContact CD2-CG2 3.89Å
324	A	89.5	Confident	88.1	Confident	43 Å²	43	31.6 Å²	31.6	36%	0.355	16%	0.16	S	C	.	.	H	α-helix	trans	-76.2	-31.4	175.4	0	0	0	0	0	112.5	F230 Y320 L321 N322 A328	F230-A324 HydrophobicContact CE1-CB 4.37Å; F230-A324 HydrophobicContact CZ-CB 4.31Å; Y320-A324 WeakPolarHBondContact O-CB 3.43Å; Y320-A324 PolarHBondContact O-N 3.47Å; Y320-A324 VanDerWaalsContact O-N 3.11Å; L321-A324 PolarHBondContact O-N 2.91Å; L321-A324 VanDerWaalsContact O-N 3.16Å; N322-A324 PolarHBondContact O-N 2.99Å; A324-A328 WeakPolarHBondContact O-CB 3.28Å; A324-A328 PolarHBondContact O-N 3.19Å
325	A	88.8	Confident	88.8	Confident	3 Å²	3	25.2 Å²	25.2	3%	0.025	13%	0.126	C	C	.	.	H	α-helix	trans	-72.5	-54.5	174.5	0	0	0	0	0	110.7	F230 L321 N322 L327 A328 H329 F427 V430	F230-A325 HydrophobicContact CE1-CB 3.69Å; F230-A325 HydrophobicContact CZ-CB 3.89Å; L321-A325 PolarHBondContact O-N 3.5Å; N322-A325 WeakPolarHBondContact O-CB 3.35Å; N322-A325 PolarHBondContact O-N 3.37Å; A325-L327 PolarHBondContact O-N 3.16Å; A325-A328 WeakPolarHBondContact O-CA 3.42Å; A325-A328 WeakPolarHBondContact O-CB 3.26Å; A325-A328 PolarHBondContact O-N 3.02Å; A325-H329 PolarHBondContact O-N 3.27Å; A325-F427 HydrophobicContact CB-CD1 3.83Å; A325-F427 HydrophobicContact CB-CE1 3.85Å; A325-V430 HydrophobicContact CB-CG2 3.86Å
326	D	90.1	Very high	89	Confident	3 Å²	3	27 Å²	27	2%	0.016	14%	0.141	C	C	.	.	H	α-helix	trans	-50.8	-54.5	174.7	169.4	2.3	0	0	0	110.6	N322 A328 H329 N330 T387	N322-D326 VanDerWaalsContact O-CB 3.29Å; N322-D326 WeakPolarHBondContact O-CB 3.38Å; N322-D326 PolarHBondContact O-N 3Å; D326-A328 PolarHBondContact O-N 2.98Å; D326-A328 VanDerWaalsContact O-N 3.1Å; D326-H329 PolarHBondContact O-N 2.99Å; D326-N330 WeakPolarHBondContact O-CB 3.37Å; D326-N330 PolarHBondContact O-N 2.94Å; D326-N330 PolarHBondContact OD1-ND2 2.98Å; D326-T387 HydrophobicContact CB-CG2 4.14Å; D326-T387 VanDerWaalsContact CG-CB 3.49Å; D326-T387 WeakPolarHBondContact OD1-CB 3.37Å; D326-T387 PolarHBondContact OD1-OG1 3.32Å; D326-T387 WeakPolarHBondContact OD2-CB 3.41Å; D326-T387 WeakPolarHBondContact OD2-CG2 3.42Å; D326-T387 PolarHBondContact OD2-OG1 3.21Å
327	L	91.4	Very high	89.2	Confident	77 Å²	77	20.4 Å²	20.4	40%	0.403	12%	0.116	S	C	.	.	H	α-helix	trans	-58.5	-29.5	177.6	-177.4	144.9	0	0	0	113.9	L323 A325 F331 T387	L323-L327 WeakPolarHBondContact O-CB 3.46Å; L323-L327 PolarHBondContact O-N 3.49Å; A325-L327 PolarHBondContact O-N 3.16Å; L327-F331 VanDerWaalsContact O-CB 3.31Å; L327-F331 WeakPolarHBondContact O-CB 3.33Å; L327-F331 PolarHBondContact O-N 3.49Å; L327-T387 HydrophobicContact CB-CG2 3.96Å
328	A	86.6	Confident	89.4	Confident	20 Å²	20	19.4 Å²	19.4	17%	0.165	11%	0.11	C	C	.	.	H	α-helix	trans	-79.9	-31.9	176.3	0	0	0	0	0	112.9	A324 A325 D326 T332	A324-A328 WeakPolarHBondContact O-CB 3.28Å; A324-A328 PolarHBondContact O-N 3.19Å; A325-A328 WeakPolarHBondContact O-CA 3.42Å; A325-A328 WeakPolarHBondContact O-CB 3.26Å; A325-A328 PolarHBondContact O-N 3.02Å; D326-A328 PolarHBondContact O-N 2.98Å; D326-A328 VanDerWaalsContact O-N 3.1Å; A328-T332 PolarHBondContact O-N 3.09Å; A328-T332 PolarHBondContact O-OG1 2.87Å
329	H	89	Confident	89.3	Confident	2 Å²	2	19.1 Å²	19.1	1%	0.009	11%	0.109	C	C	.	.	H	α-helix	trans	-72	-53.2	173	-173.4	93.5	0	0	0	110.9	D183 A325 D326 F331 T332 D333 H358 E359 T423 F427	D183-H329 IonicContact OD1-CE1 3.88Å; D183-H329 IonicContact OD2-CE1 3.99Å; D183-H329 PolarHBondContact OD2-CE1 3.37Å; D183-H329 IonicContact OD2-ND1 3.14Å; D183-H329 PolarHBondContact OD2-ND1 3.47Å; A325-H329 PolarHBondContact O-N 3.27Å; D326-H329 PolarHBondContact O-N 2.99Å; H329-F331 PolarHBondContact O-N 2.95Å; H329-T332 WeakPolarHBondContact CA-OG1 3.16Å; H329-T332 WeakPolarHBondContact O-CA 2.85Å; H329-T332 PolarHBondContact O-N 2.9Å; H329-T332 PolarHBondContact O-OG1 2.88Å; H329-D333 IonicContact CD2-OD1 3.41Å; H329-D333 IonicContact CD2-OD2 3.45Å; H329-D333 PolarHBondContact CD2-OD2 2.81Å; H329-D333 IonicContact NE2-OD1 3.63Å; H329-D333 IonicContact NE2-OD2 3.27Å; H329-D333 PolarHBondContact O-N 3.13Å; H329-D333 VanDerWaalsContact O-OD2 3.13Å; H329-H358 AromaticContact NE2-CD2 3.99Å; H329-E359 IonicContact CD2-OE1 3.13Å; H329-E359 PolarHBondContact CD2-OE1 3.39Å; H329-E359 IonicContact NE2-OE1 3.66Å; H329-T423 HydrophobicContact CB-CG2 3.91Å; H329-F427 HydrophobicContact CB-CE1 3.74Å; H329-F427 HydrophobicContact CB-CE2 4.22Å; H329-F427 HydrophobicContact CB-CZ 3.36Å; H329-F427 AromaticContact CE1-CE2 3.71Å; H329-F427 AromaticContact CG-CE2 3.78Å; H329-F427 AromaticContact CG-CZ 3.35Å; H329-F427 AromaticContact ND1-CE2 3.23Å; H329-F427 WeakPolarHBondContact ND1-CE2 3.44Å; H329-F427 AromaticContact ND1-CZ 3.32Å; H329-F427 VanDerWaalsContact ND1-CZ 3.32Å; H329-F427 WeakPolarHBondContact ND1-CZ 3.29Å
330	N	90.8	Very high	89.1	Confident	1 Å²	1	19.5 Å²	19.5	1%	0.005	11%	0.112	C	C	.	.	H	α-helix	trans	-48.9	-41.1	171.5	-105.4	-81.9	0	0	0	111	D326 D333 G334 E359 A391	D326-N330 WeakPolarHBondContact O-CB 3.37Å; D326-N330 PolarHBondContact O-N 2.94Å; D326-N330 PolarHBondContact OD1-ND2 2.98Å; N330-D333 WeakPolarHBondContact CA-OD2 3.25Å; N330-D333 PolarHBondContact O-N 3.05Å; N330-G334 PolarHBondContact O-N 3.32Å; N330-E359 PolarHBondContact ND2-OE2 3.12Å; N330-A391 HydrophobicContact CB-CB 4.08Å; N330-A391 WeakPolarHBondContact O-CA 3.43Å; N330-A391 WeakPolarHBondContact O-CB 3.49Å; N330-A391 PolarHBondContact O-N 3.28Å; N330-A391 WeakPolarHBondContact OD1-CB 3.25Å
331	F	89.8	Confident	89.1	Confident	57 Å²	57	15.2 Å²	15.2	25%	0.25	10%	0.095	C	C	.	.	H	α-helix	trans	-62.5	-41.4	173.6	177.1	-97.9	0	0	0	114.1	L327 H329 D333 L335 G390 A393 G394 V419	L327-F331 VanDerWaalsContact O-CB 3.31Å; L327-F331 WeakPolarHBondContact O-CB 3.33Å; L327-F331 PolarHBondContact O-N 3.49Å; H329-F331 PolarHBondContact O-N 2.95Å; F331-D333 VanDerWaalsContact C-N 3.34Å; F331-L335 HydrophobicContact CD1-CD1 3.66Å; F331-L335 HydrophobicContact CE1-CD1 3.29Å; F331-L335 HydrophobicContact CE1-CG 4.24Å; F331-L335 HydrophobicContact CG-CD1 4.43Å; F331-L335 HydrophobicContact CZ-CD1 3.77Å; F331-L335 HydrophobicContact CZ-CD2 4.5Å; F331-L335 HydrophobicContact CZ-CG 4.3Å; F331-L335 WeakPolarHBondContact O-CD1 3.28Å; F331-L335 WeakPolarHBondContact O-CG 3.44Å; F331-L335 PolarHBondContact O-N 3.24Å; F331-L335 VanDerWaalsContact O-N 3.1Å; F331-G390 WeakPolarHBondContact CA-O 3.42Å; F331-G390 WeakPolarHBondContact CD2-O 3.36Å; F331-A393 HydrophobicContact CD2-CB 4.21Å; F331-A393 HydrophobicContact CE2-CB 4.37Å; F331-G394 WeakPolarHBondContact O-CA 3.21Å; F331-V419 HydrophobicContact CD1-CG1 4.27Å; F331-V419 HydrophobicContact CE1-CG1 4.37Å
332	T	86.9	Confident	88.9	Confident	5 Å²	5	19.5 Å²	19.5	3%	0.031	11%	0.112	C	C	.	.	H	α-helix	trans	-66.4	-34.1	173.5	41	0	0	0	0	112.8	A328 H329 L335 A336 V419 L420	A328-T332 PolarHBondContact O-N 3.09Å; A328-T332 PolarHBondContact O-OG1 2.87Å; H329-T332 WeakPolarHBondContact CA-OG1 3.16Å; H329-T332 WeakPolarHBondContact O-CA 2.85Å; H329-T332 PolarHBondContact O-N 2.9Å; H329-T332 PolarHBondContact O-OG1 2.88Å; T332-L335 WeakPolarHBondContact O-CB 3.46Å; T332-L335 PolarHBondContact O-N 3.36Å; T332-A336 PolarHBondContact O-N 3.22Å; T332-V419 HydrophobicContact CG2-CB 4.12Å; T332-V419 HydrophobicContact CG2-CG1 3.39Å; T332-L420 HydrophobicContact CG2-CD2 3.91Å
333	D	89.7	Confident	88.4	Confident	6 Å²	6	21.8 Å²	21.8	3%	0.032	14%	0.135	C	C	.	.	H	α-helix	trans	-70.6	-41.7	178.5	-48.6	-30.5	0	0	0	111.4	I145 H329 N330 F331 L335 A336 I337 V355	I145-D333 HydrophobicContact CD1-CB 4.29Å; H329-D333 IonicContact CD2-OD1 3.41Å; H329-D333 IonicContact CD2-OD2 3.45Å; H329-D333 PolarHBondContact CD2-OD2 2.81Å; H329-D333 IonicContact NE2-OD1 3.63Å; H329-D333 IonicContact NE2-OD2 3.27Å; H329-D333 PolarHBondContact O-N 3.13Å; H329-D333 VanDerWaalsContact O-OD2 3.13Å; N330-D333 WeakPolarHBondContact CA-OD2 3.25Å; N330-D333 PolarHBondContact O-N 3.05Å; F331-D333 VanDerWaalsContact C-N 3.34Å; D333-L335 VanDerWaalsContact C-N 3.29Å; D333-L335 PolarHBondContact O-N 2.97Å; D333-A336 PolarHBondContact O-N 3.21Å; D333-A336 VanDerWaalsContact O-N 3.16Å; D333-I337 WeakPolarHBondContact O-CB 3.45Å; D333-I337 WeakPolarHBondContact O-CG1 3.29Å; D333-I337 PolarHBondContact O-N 3.43Å; D333-V355 HydrophobicContact CB-CG1 3.78Å; D333-V355 HydrophobicContact CB-CG2 4.31Å
334	G	91.5	Very high	88	Confident	0 Å²	0	21.4 Å²	21.4	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-57.4	-43.7	171.4	0	0	0	0	0	112	N330 A336 I337 G338 A391 G394 T395	N330-G334 PolarHBondContact O-N 3.32Å; G334-A336 PolarHBondContact O-N 3.4Å; G334-I337 PolarHBondContact O-N 3.1Å; G334-G338 PolarHBondContact O-N 3.47Å; G334-A391 WeakPolarHBondContact CA-O 3.32Å; G334-G394 VanDerWaalsContact C-C 3.47Å; G334-T395 VanDerWaalsContact C-N 3.27Å; G334-T395 WeakPolarHBondContact CA-OG1 3.35Å; G334-T395 WeakPolarHBondContact O-CA 3.48Å; G334-T395 PolarHBondContact O-N 3.04Å; G334-T395 PolarHBondContact O-OG1 3.09Å
335	L	88.1	Confident	88	Confident	2 Å²	2	24.3 Å²	24.3	1%	0.01	14%	0.139	C	C	.	.	H	α-helix	trans	-59.3	-46.5	173.8	-73.8	159.2	0	0	0	111.5	F331 T332 D333 G338 A339 G394 C397 A398 V406 I410	F331-L335 HydrophobicContact CD1-CD1 3.66Å; F331-L335 HydrophobicContact CE1-CD1 3.29Å; F331-L335 HydrophobicContact CE1-CG 4.24Å; F331-L335 HydrophobicContact CG-CD1 4.43Å; F331-L335 HydrophobicContact CZ-CD1 3.77Å; F331-L335 HydrophobicContact CZ-CD2 4.5Å; F331-L335 HydrophobicContact CZ-CG 4.3Å; F331-L335 WeakPolarHBondContact O-CD1 3.28Å; F331-L335 WeakPolarHBondContact O-CG 3.44Å; F331-L335 PolarHBondContact O-N 3.24Å; F331-L335 VanDerWaalsContact O-N 3.1Å; T332-L335 WeakPolarHBondContact O-CB 3.46Å; T332-L335 PolarHBondContact O-N 3.36Å; D333-L335 VanDerWaalsContact C-N 3.29Å; D333-L335 PolarHBondContact O-N 2.97Å; L335-G338 PolarHBondContact O-N 2.77Å; L335-A339 VanDerWaalsContact O-CB 3.24Å; L335-A339 WeakPolarHBondContact O-CB 3.34Å; L335-A339 PolarHBondContact O-N 3.14Å; L335-G394 WeakPolarHBondContact CD2-O 3.16Å; L335-C397 HydrophobicContact CD2-CB 3.95Å; L335-A398 HydrophobicContact CD2-CB 4.21Å; L335-A398 WeakPolarHBondContact O-CB 3.45Å; L335-V406 HydrophobicContact CD2-CG1 3.84Å; L335-I410 HydrophobicContact CB-CD1 4.3Å; L335-I410 HydrophobicContact CD1-CD1 3.56Å; L335-I410 HydrophobicContact CD2-CD1 4.1Å; L335-I410 HydrophobicContact CG-CD1 4.2Å
336	A	86.3	Confident	88	Confident	40 Å²	40	26.9 Å²	26.9	33%	0.331	17%	0.166	S	C	.	.	H	α-helix	trans	-63.2	-42.8	178.2	0	0	0	0	0	112.5	T332 D333 G334 A339 S340 T351	T332-A336 PolarHBondContact O-N 3.22Å; D333-A336 PolarHBondContact O-N 3.21Å; D333-A336 VanDerWaalsContact O-N 3.16Å; G334-A336 PolarHBondContact O-N 3.4Å; A336-A339 PolarHBondContact O-N 3.25Å; A336-S340 VanDerWaalsContact O-CB 3.23Å; A336-S340 WeakPolarHBondContact O-CB 3.35Å; A336-S340 PolarHBondContact O-N 3.35Å; A336-S340 PolarHBondContact O-OG 2.82Å; A336-T351 HydrophobicContact CB-CG2 4.1Å
337	I	90.9	Very high	87.8	Confident	0 Å²	0	30.9 Å²	30.9	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-64.4	-47.3	175.6	-72	175.7	0	0	0	110.9	A141 I145 D333 G334 A339 S340 F341 T351 V355	A141-I337 HydrophobicContact CB-CG2 3.89Å; I145-I337 HydrophobicContact CD1-CD1 3.6Å; I145-I337 HydrophobicContact CG1-CD1 4.15Å; I145-I337 HydrophobicContact CG2-CD1 4.08Å; D333-I337 WeakPolarHBondContact O-CB 3.45Å; D333-I337 WeakPolarHBondContact O-CG1 3.29Å; D333-I337 PolarHBondContact O-N 3.43Å; G334-I337 PolarHBondContact O-N 3.1Å; I337-A339 VanDerWaalsContact C-N 3.32Å; I337-A339 PolarHBondContact O-N 2.97Å; I337-S340 WeakPolarHBondContact CA-OG 3.32Å; I337-S340 PolarHBondContact O-N 3.37Å; I337-S340 PolarHBondContact O-OG 2.9Å; I337-F341 HydrophobicContact CG2-CD2 3.86Å; I337-F341 HydrophobicContact CG2-CE2 4Å; I337-F341 WeakPolarHBondContact O-CD2 3.24Å; I337-F341 PolarHBondContact O-N 2.81Å; I337-F341 VanDerWaalsContact O-N 3.09Å; I337-T351 HydrophobicContact CG1-CG2 4.32Å; I337-V355 HydrophobicContact CD1-CB 4.48Å; I337-V355 HydrophobicContact CD1-CG1 4.39Å
338	G	89.3	Confident	87.6	Confident	0 Å²	0	27.2 Å²	27.2	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-62.9	-37.4	177.3	0	0	0	0	0	113	G334 L335 R342	G334-G338 PolarHBondContact O-N 3.47Å; L335-G338 PolarHBondContact O-N 2.77Å; G338-R342 PolarHBondContact O-N 3.23Å
339	A	85.1	Confident	87.9	Confident	16 Å²	16	30.2 Å²	30.2	13%	0.132	18%	0.18	C	C	.	.	H	α-helix	trans	-67.9	-50.5	175.9	0	0	0	0	0	112.3	L335 A336 I337 F341 R342 G343	L335-A339 VanDerWaalsContact O-CB 3.24Å; L335-A339 WeakPolarHBondContact O-CB 3.34Å; L335-A339 PolarHBondContact O-N 3.14Å; A336-A339 PolarHBondContact O-N 3.25Å; I337-A339 VanDerWaalsContact C-N 3.32Å; I337-A339 PolarHBondContact O-N 2.97Å; A339-F341 PolarHBondContact O-N 3.43Å; A339-R342 WeakPolarHBondContact O-CA 3.24Å; A339-R342 WeakPolarHBondContact O-CB 3.45Å; A339-R342 PolarHBondContact O-N 3.3Å; A339-R342 VanDerWaalsContact O-N 3.07Å; A339-G343 PolarHBondContact O-N 3.3Å
340	S	85.7	Confident	87.9	Confident	8 Å²	8	35 Å²	35	6%	0.056	21%	0.205	C	C	.	.	H	α-helix	trans	-63.8	-41.4	-176.3	52.5	0	0	0	0	112.6	A336 I337 R342 G343 G344 G348 T351	A336-S340 VanDerWaalsContact O-CB 3.23Å; A336-S340 WeakPolarHBondContact O-CB 3.35Å; A336-S340 PolarHBondContact O-N 3.35Å; A336-S340 PolarHBondContact O-OG 2.82Å; I337-S340 WeakPolarHBondContact CA-OG 3.32Å; I337-S340 PolarHBondContact O-N 3.37Å; I337-S340 PolarHBondContact O-OG 2.9Å; S340-R342 VanDerWaalsContact C-N 3.27Å; S340-R342 PolarHBondContact O-N 2.89Å; S340-G343 CarbonylContact O-C 3.35Å; S340-G343 WeakPolarHBondContact O-CA 3.46Å; S340-G343 PolarHBondContact O-N 2.9Å; S340-G343 VanDerWaalsContact O-N 3.12Å; S340-G344 PolarHBondContact O-N 3.4Å; S340-G348 PolarHBondContact O-N 3.46Å; S340-T351 WeakPolarHBondContact CB-OG1 3.49Å; S340-T351 WeakPolarHBondContact OG-CB 3.47Å; S340-T351 PolarHBondContact OG-OG1 3.09Å
341	F	89.7	Confident	87.8	Confident	9 Å²	9	36.4 Å²	36.4	4%	0.039	21%	0.213	C	C	.	.	H	α-helix	trans	-62.9	-32.4	172.6	-88.8	-71	0	0	0	113	L129 L134 Y137 A138 A141 I337 A339 G344 G348 I349 T352	L129-F341 HydrophobicContact CD1-CD1 4.49Å; L134-F341 HydrophobicContact CD1-CB 3.87Å; L134-F341 WeakPolarHBondContact CD1-O 3.46Å; Y137-F341 HydrophobicContact CD2-CE1 4.33Å; Y137-F341 HydrophobicContact CG-CE1 4.4Å; A138-F341 HydrophobicContact CB-CB 4.11Å; A138-F341 HydrophobicContact CB-CD2 3.97Å; A138-F341 HydrophobicContact CB-CG 4.2Å; A141-F341 HydrophobicContact CB-CE2 3.53Å; A141-F341 HydrophobicContact CB-CZ 4.08Å; I337-F341 HydrophobicContact CG2-CD2 3.86Å; I337-F341 HydrophobicContact CG2-CE2 4Å; I337-F341 WeakPolarHBondContact O-CD2 3.24Å; I337-F341 PolarHBondContact O-N 2.81Å; I337-F341 VanDerWaalsContact O-N 3.09Å; A339-F341 PolarHBondContact O-N 3.43Å; F341-G344 CarbonylContact O-C 3.6Å; F341-G344 WeakPolarHBondContact O-CA 3.46Å; F341-G344 PolarHBondContact O-N 3.41Å; F341-G348 WeakPolarHBondContact CE2-O 3.44Å; F341-G348 VanDerWaalsContact CZ-C 3.47Å; F341-I349 HydrophobicContact CE1-CG1 4.23Å; F341-I349 HydrophobicContact CZ-CG1 4.22Å; F341-T352 WeakPolarHBondContact CE2-OG1 3.23Å
342	R	85.9	Confident	87.9	Confident	92 Å²	92	33.9 Å²	33.9	35%	0.347	20%	0.203	S	C	.	.	H	α-helix	trans	-71.3	-32.4	173.5	-157.2	-173.1	-165.1	111.1	3.3	112.3	L134 G338 A339 S340 G344 L399 T401 G404	L134-R342 HydrophobicContact CD2-CG 4.4Å; G338-R342 PolarHBondContact O-N 3.23Å; A339-R342 WeakPolarHBondContact O-CA 3.24Å; A339-R342 WeakPolarHBondContact O-CB 3.45Å; A339-R342 PolarHBondContact O-N 3.3Å; A339-R342 VanDerWaalsContact O-N 3.07Å; S340-R342 VanDerWaalsContact C-N 3.27Å; S340-R342 PolarHBondContact O-N 2.89Å; R342-G344 VanDerWaalsContact C-N 3.25Å; R342-L399 PolarHBondContact NH1-O 3.01Å; R342-T401 VanDerWaalsContact CZ-O 3.23Å; R342-T401 PolarHBondContact NH1-O 3.31Å; R342-T401 PolarHBondContact NH2-O 2.9Å; R342-G404 VanDerWaalsContact CD-CA 3.47Å
343	G	79.2	Confident	88.1	Confident	47 Å²	47	38.1 Å²	38.1	49%	0.485	22%	0.223	S	C	.	.	H	α-helix	trans	-68.6	-22.8	169	0	0	0	0	0	113.7	A339 S340	A339-G343 PolarHBondContact O-N 3.3Å; S340-G343 CarbonylContact O-C 3.35Å; S340-G343 WeakPolarHBondContact O-CA 3.46Å; S340-G343 PolarHBondContact O-N 2.9Å; S340-G343 VanDerWaalsContact O-N 3.12Å
344	G	83.9	Confident	88	Confident	18 Å²	18	38.8 Å²	38.8	19%	0.186	23%	0.228	C	C	.	.			trans	144.6	155.5	167.3	0	0	0	0	0	112.7	S340 F341 R342 G346 L347 G348	S340-G344 PolarHBondContact O-N 3.4Å; F341-G344 CarbonylContact O-C 3.6Å; F341-G344 WeakPolarHBondContact O-CA 3.46Å; F341-G344 PolarHBondContact O-N 3.41Å; R342-G344 VanDerWaalsContact C-N 3.25Å; G344-G346 VanDerWaalsContact C-N 3.26Å; G344-G346 PolarHBondContact O-N 3.13Å; G344-G346 VanDerWaalsContact O-N 3.09Å; G344-L347 PolarHBondContact O-N 2.8Å; G344-G348 PolarHBondContact O-N 3.05Å
345	R	90.2	Very high	87.9	Confident	104 Å²	104	39 Å²	39	39%	0.392	23%	0.229	S	C	.	.	H	α-helix	trans	-49.1	-41.8	-176.1	-176	179	61.3	166.8	-6.1	114.5	L129 Y137 I349	L129-R345 HydrophobicContact CD1-CB 4.16Å; L129-R345 HydrophobicContact CD2-CB 4.34Å; Y137-R345 HydrophobicContact CD2-CG 4.28Å; Y137-R345 HydrophobicContact CE2-CG 4.14Å; R345-I349 HydrophobicContact CG-CD1 3.87Å; R345-I349 VanDerWaalsContact O-CG1 3.29Å; R345-I349 WeakPolarHBondContact O-CG1 3.46Å; R345-I349 PolarHBondContact O-N 3.01Å
346	G	88.6	Confident	88	Confident	57 Å²	57	40.7 Å²	40.7	59%	0.588	24%	0.238	S	C	*	.	H	α-helix	trans	-66.6	-40.9	-179	0	0	0	0	0	112.9	G344 L350	G344-G346 VanDerWaalsContact C-N 3.26Å; G344-G346 PolarHBondContact O-N 3.13Å; G344-G346 VanDerWaalsContact O-N 3.09Å; G346-L350 PolarHBondContact O-N 3.02Å; G346-L350 VanDerWaalsContact O-N 3.09Å
347	L	84.5	Confident	88.1	Confident	88 Å²	88	42 Å²	42	46%	0.461	24%	0.239	S	C	.	.	H	α-helix	trans	-67.7	-46.6	176.3	-175	64	0	0	0	110.4	G344 I349 L350 T351	G344-L347 PolarHBondContact O-N 2.8Å; L347-I349 VanDerWaalsContact C-N 3.34Å; L347-I349 PolarHBondContact O-N 3.1Å; L347-L350 WeakPolarHBondContact O-CB 3.4Å; L347-L350 PolarHBondContact O-N 3.03Å; L347-L350 VanDerWaalsContact O-N 3.1Å; L347-T351 PolarHBondContact O-N 3.11Å; L347-T351 PolarHBondContact O-OG1 3.27Å
348	G	89.2	Confident	87.9	Confident	0 Å²	0	42 Å²	42	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-55.6	-43.8	175.2	0	0	0	0	0	114	S340 F341 G344 T352	S340-G348 PolarHBondContact O-N 3.46Å; F341-G348 WeakPolarHBondContact CE2-O 3.44Å; F341-G348 VanDerWaalsContact CZ-C 3.47Å; G344-G348 PolarHBondContact O-N 3.05Å; G348-T352 WeakPolarHBondContact O-CB 3.42Å; G348-T352 PolarHBondContact O-N 3.1Å; G348-T352 PolarHBondContact O-OG1 3.09Å
349	I	92.8	Very high	87.9	Confident	83 Å²	83	42.1 Å²	42.1	43%	0.426	24%	0.24	S	C	.	.	H	α-helix	trans	-65	-42.2	175.3	-68.6	167.1	0	0	0	111.2	F341 R345 L347 T352 M353	F341-I349 HydrophobicContact CE1-CG1 4.23Å; F341-I349 HydrophobicContact CZ-CG1 4.22Å; R345-I349 HydrophobicContact CG-CD1 3.87Å; R345-I349 VanDerWaalsContact O-CG1 3.29Å; R345-I349 WeakPolarHBondContact O-CG1 3.46Å; R345-I349 PolarHBondContact O-N 3.01Å; L347-I349 VanDerWaalsContact C-N 3.34Å; L347-I349 PolarHBondContact O-N 3.1Å; I349-T352 PolarHBondContact O-N 2.86Å; I349-M353 VanDerWaalsContact O-CG 3.28Å; I349-M353 WeakPolarHBondContact O-CG 3.1Å; I349-M353 PolarHBondContact O-N 2.92Å
350	L	89.1	Confident	87.9	Confident	102 Å²	102	42.9 Å²	42.9	53%	0.534	24%	0.243	S	C	.	.	H	α-helix	trans	-61.5	-53.1	178	-179.3	60.8	0	0	0	111	G346 L347 T352 M353 T354	G346-L350 PolarHBondContact O-N 3.02Å; G346-L350 VanDerWaalsContact O-N 3.09Å; L347-L350 WeakPolarHBondContact O-CB 3.4Å; L347-L350 PolarHBondContact O-N 3.03Å; L347-L350 VanDerWaalsContact O-N 3.1Å; L350-T352 VanDerWaalsContact C-N 3.29Å; L350-T352 PolarHBondContact O-N 2.92Å; L350-M353 PolarHBondContact O-N 3.23Å; L350-T354 PolarHBondContact O-N 3.05Å; L350-T354 PolarHBondContact O-OG1 3.16Å
351	T	88.3	Confident	87.8	Confident	30 Å²	30	43 Å²	43	18%	0.184	24%	0.243	C	C	.	.	H	α-helix	trans	-57.5	-40.1	176.6	-57.3	0	0	0	0	111.9	A336 I337 S340 L347 M353 T354 V355	A336-T351 HydrophobicContact CB-CG2 4.1Å; I337-T351 HydrophobicContact CG1-CG2 4.32Å; S340-T351 WeakPolarHBondContact CB-OG1 3.49Å; S340-T351 WeakPolarHBondContact OG-CB 3.47Å; S340-T351 PolarHBondContact OG-OG1 3.09Å; L347-T351 PolarHBondContact O-N 3.11Å; L347-T351 PolarHBondContact O-OG1 3.27Å; T351-M353 VanDerWaalsContact C-N 3.32Å; T351-M353 PolarHBondContact O-N 3.04Å; T351-T354 PolarHBondContact O-N 3.39Å; T351-V355 HydrophobicContact CG2-CG2 4.33Å; T351-V355 WeakPolarHBondContact O-CB 3.49Å; T351-V355 VanDerWaalsContact O-CG2 3.3Å; T351-V355 WeakPolarHBondContact O-CG2 3.38Å; T351-V355 PolarHBondContact O-N 3.18Å
352	T	91.9	Very high	87.7	Confident	5 Å²	5	43 Å²	43	3%	0.031	24%	0.243	C	C	.	.	H	α-helix	trans	-60.5	-40.7	174.8	-55.1	0	0	0	0	112.1	A141 I145 F341 G348 I349 L350 L356	A141-T352 HydrophobicContact CB-CG2 3.64Å; A141-T352 VanDerWaalsContact CB-OG1 3.32Å; A141-T352 WeakPolarHBondContact CB-OG1 3.09Å; I145-T352 HydrophobicContact CG2-CG2 4.05Å; F341-T352 WeakPolarHBondContact CE2-OG1 3.23Å; G348-T352 WeakPolarHBondContact O-CB 3.42Å; G348-T352 PolarHBondContact O-N 3.1Å; G348-T352 PolarHBondContact O-OG1 3.09Å; I349-T352 PolarHBondContact O-N 2.86Å; L350-T352 VanDerWaalsContact C-N 3.29Å; L350-T352 PolarHBondContact O-N 2.92Å; T352-L356 WeakPolarHBondContact O-CB 3.1Å; T352-L356 PolarHBondContact O-N 2.88Å
353	M	90.6	Very high	87.8	Confident	93 Å²	93	38.9 Å²	38.9	46%	0.458	23%	0.228	S	C	.	.	H	α-helix	trans	-73.1	-38.6	179.8	-66.9	-69	151.8	0	0	111.9	I349 L350 T351 L356 L357	I349-M353 VanDerWaalsContact O-CG 3.28Å; I349-M353 WeakPolarHBondContact O-CG 3.1Å; I349-M353 PolarHBondContact O-N 2.92Å; L350-M353 PolarHBondContact O-N 3.23Å; T351-M353 VanDerWaalsContact C-N 3.32Å; T351-M353 PolarHBondContact O-N 3.04Å; M353-L356 HydrophobicContact SD-CD2 4.49Å; M353-L357 VanDerWaalsContact O-CG 3.26Å; M353-L357 WeakPolarHBondContact O-CG 3.1Å; M353-L357 PolarHBondContact O-N 2.91Å
354	T	86.9	Confident	88.2	Confident	21 Å²	21	36.7 Å²	36.7	13%	0.129	21%	0.205	C	C	.	.	H	α-helix	trans	-57.2	-55.3	170.8	-67.6	0	0	0	0	111	L350 T351 L356 L357 H358 E469	L350-T354 PolarHBondContact O-N 3.05Å; L350-T354 PolarHBondContact O-OG1 3.16Å; T351-T354 PolarHBondContact O-N 3.39Å; T354-L356 VanDerWaalsContact C-N 3.35Å; T354-L356 PolarHBondContact O-N 2.65Å; T354-L357 WeakPolarHBondContact O-CB 3.32Å; T354-L357 PolarHBondContact O-N 2.87Å; T354-H358 PolarHBondContact O-N 2.94Å; T354-E469 HydrophobicContact CG2-CG 3.4Å; T354-E469 WeakPolarHBondContact CG2-OE1 3.07Å
355	V	90	Very high	88.4	Confident	5 Å²	5	35.9 Å²	35.9	3%	0.03	20%	0.197	C	C	.	.	H	α-helix	trans	-59.6	-46.2	-178.9	169.5	0	0	0	0	111.2	I145 D333 I337 T351 L357 H358 E359	I145-V355 HydrophobicContact CB-CG1 4.36Å; I145-V355 HydrophobicContact CD1-CG1 3.61Å; I145-V355 HydrophobicContact CG2-CB 4.49Å; I145-V355 HydrophobicContact CG2-CG1 4.07Å; D333-V355 HydrophobicContact CB-CG1 3.78Å; D333-V355 HydrophobicContact CB-CG2 4.31Å; I337-V355 HydrophobicContact CD1-CB 4.48Å; I337-V355 HydrophobicContact CD1-CG1 4.39Å; T351-V355 HydrophobicContact CG2-CG2 4.33Å; T351-V355 WeakPolarHBondContact O-CB 3.49Å; T351-V355 VanDerWaalsContact O-CG2 3.3Å; T351-V355 WeakPolarHBondContact O-CG2 3.38Å; T351-V355 PolarHBondContact O-N 3.18Å; V355-L357 PolarHBondContact O-N 2.8Å; V355-L357 VanDerWaalsContact O-N 3.07Å; V355-H358 WeakPolarHBondContact CA-NE2 3.42Å; V355-H358 PolarHBondContact O-CD2 3.41Å; V355-H358 PolarHBondContact O-N 2.87Å; V355-H358 VanDerWaalsContact O-N 3.09Å; V355-E359 HydrophobicContact CG1-CG 3.75Å; V355-E359 WeakPolarHBondContact O-CB 3.32Å; V355-E359 PolarHBondContact O-N 2.97Å
356	L	90.6	Very high	88.4	Confident	36 Å²	36	31.1 Å²	31.1	19%	0.188	18%	0.179	C	C	.	.	H	α-helix	trans	-55	-30	176.3	-178.8	61.9	0	0	0	113.5	I145 A148 T352 M353 T354 V360	I145-L356 HydrophobicContact CG2-CB 4.18Å; A148-L356 HydrophobicContact CB-CD1 3.44Å; A148-L356 VanDerWaalsContact CB-CD1 3.44Å; T352-L356 WeakPolarHBondContact O-CB 3.1Å; T352-L356 PolarHBondContact O-N 2.88Å; M353-L356 HydrophobicContact SD-CD2 4.49Å; T354-L356 VanDerWaalsContact C-N 3.35Å; T354-L356 PolarHBondContact O-N 2.65Å; L356-V360 HydrophobicContact CD1-CG2 4.2Å
357	L	87.2	Confident	88.5	Confident	68 Å²	68	28.5 Å²	28.5	36%	0.356	15%	0.152	S	C	.	.	H	α-helix	trans	-77.1	-31.4	179.7	-72.6	166.7	0	0	0	113.3	M353 T354 V355 P361 I465 L468	M353-L357 VanDerWaalsContact O-CG 3.26Å; M353-L357 WeakPolarHBondContact O-CG 3.1Å; M353-L357 PolarHBondContact O-N 2.91Å; T354-L357 WeakPolarHBondContact O-CB 3.32Å; T354-L357 PolarHBondContact O-N 2.87Å; V355-L357 PolarHBondContact O-N 2.8Å; V355-L357 VanDerWaalsContact O-N 3.07Å; L357-P361 WeakPolarHBondContact O-CD 3.3Å; L357-P361 VanDerWaalsContact O-CG 3.29Å; L357-P361 WeakPolarHBondContact O-CG 3.37Å; L357-I465 HydrophobicContact CB-CD1 4.39Å; L357-I465 HydrophobicContact CB-CG1 4.5Å; L357-I465 WeakPolarHBondContact O-CD1 3.19Å; L357-L468 HydrophobicContact CD1-CD1 4.02Å
358	H	87.7	Confident	88.7	Confident	1 Å²	1	24.3 Å²	24.3	1%	0.005	13%	0.13	C	C	.	.	H	α-helix	trans	-87.7	-33	172.5	53	-130.9	0	0	0	112.8	H187 H329 T354 V355 V360 P361 H362 M462 I465 E469	H187-H358 AromaticContact NE2-CE1 3.96Å; H329-H358 AromaticContact NE2-CD2 3.99Å; T354-H358 PolarHBondContact O-N 2.94Å; V355-H358 WeakPolarHBondContact CA-NE2 3.42Å; V355-H358 PolarHBondContact O-CD2 3.41Å; V355-H358 PolarHBondContact O-N 2.87Å; V355-H358 VanDerWaalsContact O-N 3.09Å; H358-V360 PolarHBondContact O-N 3.17Å; H358-P361 WeakPolarHBondContact O-CB 3.31Å; H358-P361 WeakPolarHBondContact O-CD 3.44Å; H358-H362 PolarHBondContact O-CD2 3.49Å; H358-H362 PolarHBondContact O-N 3.33Å; H358-M462 HydrophobicContact CB-CE 4Å; H358-M462 HydrophobicContact CB-SD 4.2Å; H358-I465 HydrophobicContact CB-CD1 3.76Å; H358-I465 HydrophobicContact CB-CG2 4.36Å; H358-E469 IonicContact ND1-OE1 3.4Å
359	E	88	Confident	88.7	Confident	2 Å²	2	24.5 Å²	24.5	1%	0.009	13%	0.131	C	C	.	.	H	α-helix	trans	-63.9	-43.4	-178.5	-85.3	-61.8	92.6	0	0	113.7	H329 N330 V355 H362 E363	H329-E359 IonicContact CD2-OE1 3.13Å; H329-E359 PolarHBondContact CD2-OE1 3.39Å; H329-E359 IonicContact NE2-OE1 3.66Å; N330-E359 PolarHBondContact ND2-OE2 3.12Å; V355-E359 HydrophobicContact CG1-CG 3.75Å; V355-E359 WeakPolarHBondContact O-CB 3.32Å; V355-E359 PolarHBondContact O-N 2.97Å; E359-H362 PolarHBondContact O-N 3.26Å; E359-E363 VanDerWaalsContact O-CB 3.28Å; E359-E363 WeakPolarHBondContact O-CB 3.42Å; E359-E363 WeakPolarHBondContact O-CG 3.39Å; E359-E363 PolarHBondContact O-N 2.89Å
360	V	85.8	Confident	88.7	Confident	32 Å²	32	20.5 Å²	20.5	19%	0.194	11%	0.11	C	C	.	.	H	α-helix	trans	-56.9	-46.4	177.4	165.8	0	0	0	0	111.9	P149 V152 L356 H358 V364	P149-V360 HydrophobicContact CG-CG2 4.08Å; V152-V360 HydrophobicContact CB-CG1 4.39Å; V152-V360 HydrophobicContact CG1-CG1 4.25Å; V152-V360 HydrophobicContact CG2-CG1 3.89Å; L356-V360 HydrophobicContact CD1-CG2 4.2Å; H358-V360 PolarHBondContact O-N 3.17Å; V360-V364 VanDerWaalsContact O-CG2 3.27Å; V360-V364 WeakPolarHBondContact O-CG2 3.5Å; V360-V364 PolarHBondContact O-N 3.19Å
361	P	82.8	Confident	88.7	Confident	11 Å²	11	16.8 Å²	16.8	7%	0.071	9%	0.092	C	C	.	.	H	α-helix	trans	-59.4	-46.9	168.1	-28.1	32.5	0	0	0	116.5	F175 L357 H358 V364 G365 M461	F175-P361 HydrophobicContact CE1-CB 4.11Å; F175-P361 HydrophobicContact CZ-CB 4.27Å; L357-P361 WeakPolarHBondContact O-CD 3.3Å; L357-P361 VanDerWaalsContact O-CG 3.29Å; L357-P361 WeakPolarHBondContact O-CG 3.37Å; H358-P361 WeakPolarHBondContact O-CB 3.31Å; H358-P361 WeakPolarHBondContact O-CD 3.44Å; P361-V364 PolarHBondContact O-N 3Å; P361-G365 PolarHBondContact O-N 2.89Å; P361-G365 VanDerWaalsContact O-N 3.11Å; P361-M461 HydrophobicContact CB-CE 3.53Å; P361-M461 HydrophobicContact CB-SD 3.27Å; P361-M461 WeakPolarHBondContact CB-SD 3.39Å; P361-M461 HydrophobicContact CG-CE 3.73Å; P361-M461 HydrophobicContact CG-SD 3.13Å; P361-M461 WeakPolarHBondContact CG-SD 3.37Å
362	H	87.8	Confident	88.7	Confident	8 Å²	8	17.4 Å²	17.4	4%	0.037	9%	0.093	C	C	.	.	H	α-helix	trans	-60.8	-48.9	-179.3	-82.7	-69.9	0	0	0	110.8	H358 E359 V364 G365 D366 F427	H358-H362 PolarHBondContact O-CD2 3.49Å; H358-H362 PolarHBondContact O-N 3.33Å; E359-H362 PolarHBondContact O-N 3.26Å; H362-V364 VanDerWaalsContact C-N 3.31Å; H362-V364 PolarHBondContact O-N 3.32Å; H362-G365 CarbonylContact O-C 3.56Å; H362-G365 WeakPolarHBondContact O-CA 3.3Å; H362-G365 PolarHBondContact O-N 3.15Å; H362-D366 PolarHBondContact O-N 3.44Å; H362-F427 AromaticContact CE1-CE2 3.79Å
363	E	89.3	Confident	88.5	Confident	6 Å²	6	17.3 Å²	17.3	3%	0.028	9%	0.092	C	C	.	.	H	α-helix	trans	-62.8	-32	177.7	-77.2	-90.9	-122.4	0	0	113.5	P149 E359 G365 F367 Q384	P149-E363 HydrophobicContact CB-CB 3.49Å; P149-E363 VanDerWaalsContact CB-CB 3.49Å; P149-E363 HydrophobicContact CB-CG 3.69Å; P149-E363 HydrophobicContact CG-CB 4.04Å; P149-E363 HydrophobicContact CG-CG 3.79Å; E359-E363 VanDerWaalsContact O-CB 3.28Å; E359-E363 WeakPolarHBondContact O-CB 3.42Å; E359-E363 WeakPolarHBondContact O-CG 3.39Å; E359-E363 PolarHBondContact O-N 2.89Å; E363-G365 VanDerWaalsContact C-N 3.33Å; E363-F367 WeakPolarHBondContact O-CB 3.4Å; E363-F367 PolarHBondContact O-N 3Å; E363-Q384 PolarHBondContact O-NE2 3.44Å; E363-Q384 VanDerWaalsContact OE2-CB 3.25Å; E363-Q384 WeakPolarHBondContact OE2-CB 3.47Å; E363-Q384 WeakPolarHBondContact OE2-CG 3.13Å; E363-Q384 PolarHBondContact OE2-NE2 3.29Å
364	V	86.9	Confident	88.4	Confident	1 Å²	1	15.5 Å²	15.5	1%	0.006	10%	0.098	C	C	.	.	H	α-helix	trans	-64.6	-40.3	169.5	164	0	0	0	0	111.4	W18 V152 L153 I156 L172 V360 P361 H362 A368	W18-V364 HydrophobicContact CH2-CG1 3.75Å; W18-V364 HydrophobicContact CH2-CG2 4.18Å; W18-V364 HydrophobicContact CZ2-CB 4.42Å; W18-V364 HydrophobicContact CZ2-CG1 3.89Å; W18-V364 HydrophobicContact CZ2-CG2 4.18Å; V152-V364 HydrophobicContact CG1-CG2 4.2Å; L153-V364 HydrophobicContact CD2-CG2 4.17Å; I156-V364 HydrophobicContact CD1-CG1 4.4Å; I156-V364 HydrophobicContact CD1-CG2 4.13Å; L172-V364 HydrophobicContact CD2-CG1 3.87Å; V360-V364 VanDerWaalsContact O-CG2 3.27Å; V360-V364 WeakPolarHBondContact O-CG2 3.5Å; V360-V364 PolarHBondContact O-N 3.19Å; P361-V364 PolarHBondContact O-N 3Å; H362-V364 VanDerWaalsContact C-N 3.31Å; H362-V364 PolarHBondContact O-N 3.32Å; V364-A368 PolarHBondContact O-N 2.93Å
365	G	87.8	Confident	88.4	Confident	1 Å²	1	14.9 Å²	14.9	1%	0.01	9%	0.094	C	C	.	.	H	α-helix	trans	-69.4	-47.3	178.4	0	0	0	0	0	112.8	P361 H362 E363 F367 A368 I369	P361-G365 PolarHBondContact O-N 2.89Å; P361-G365 VanDerWaalsContact O-N 3.11Å; H362-G365 CarbonylContact O-C 3.56Å; H362-G365 WeakPolarHBondContact O-CA 3.3Å; H362-G365 PolarHBondContact O-N 3.15Å; E363-G365 VanDerWaalsContact C-N 3.33Å; G365-F367 VanDerWaalsContact C-N 3.26Å; G365-F367 PolarHBondContact O-N 3.4Å; G365-A368 WeakPolarHBondContact O-CA 3.29Å; G365-A368 WeakPolarHBondContact O-CB 3.43Å; G365-A368 PolarHBondContact O-N 3.04Å; G365-I369 WeakPolarHBondContact O-CG1 3.48Å; G365-I369 PolarHBondContact O-N 3.42Å
366	D	89.8	Confident	88.3	Confident	4 Å²	4	17.4 Å²	17.4	2%	0.021	11%	0.112	C	C	.	.	H	α-helix	trans	-62.1	-35.9	177.5	-71.6	-18.9	0	0	0	111.8	N322 H362 A368 I369 L370	N322-D366 VanDerWaalsContact ND2-CB 3.29Å; N322-D366 WeakPolarHBondContact ND2-CB 3.45Å; N322-D366 PolarHBondContact ND2-OD1 3.28Å; N322-D366 PolarHBondContact OD1-OD1 3.48Å; H362-D366 PolarHBondContact O-N 3.44Å; D366-A368 PolarHBondContact O-N 2.91Å; D366-I369 PolarHBondContact O-N 3.45Å; D366-L370 WeakPolarHBondContact O-CB 3.42Å; D366-L370 WeakPolarHBondContact O-CG 3.37Å; D366-L370 PolarHBondContact O-N 3.14Å
367	F	90.6	Very high	88.1	Confident	1 Å²	1	16.8 Å²	16.8	0%	0.004	11%	0.107	C	C	.	.	H	α-helix	trans	-61.8	-43.6	172.8	173.5	-96.3	0	0	0	111.6	L153 V158 E363 G365 L370 V371 K377 A380 M381	L153-F367 HydrophobicContact CD1-CB 4.34Å; L153-F367 HydrophobicContact CD1-CD2 4.34Å; L153-F367 HydrophobicContact CD2-CB 3.56Å; L153-F367 HydrophobicContact CD2-CD1 4.05Å; L153-F367 HydrophobicContact CD2-CD2 4.08Å; L153-F367 HydrophobicContact CD2-CG 3.63Å; V158-F367 HydrophobicContact CB-CE1 3.96Å; V158-F367 HydrophobicContact CB-CZ 3.96Å; V158-F367 HydrophobicContact CG1-CE1 3.66Å; V158-F367 HydrophobicContact CG1-CZ 3.58Å; V158-F367 HydrophobicContact CG2-CE1 3.66Å; V158-F367 HydrophobicContact CG2-CZ 4.17Å; E363-F367 WeakPolarHBondContact O-CB 3.4Å; E363-F367 PolarHBondContact O-N 3Å; G365-F367 VanDerWaalsContact C-N 3.26Å; G365-F367 PolarHBondContact O-N 3.4Å; F367-L370 PolarHBondContact O-N 3.43Å; F367-V371 HydrophobicContact CD2-CG2 4.47Å; F367-V371 HydrophobicContact CE1-CG2 4.14Å; F367-V371 HydrophobicContact CE2-CG2 4.08Å; F367-V371 HydrophobicContact CZ-CG2 3.9Å; F367-V371 WeakPolarHBondContact O-CB 3.41Å; F367-V371 VanDerWaalsContact O-CG2 3.3Å; F367-V371 WeakPolarHBondContact O-CG2 3.32Å; F367-V371 PolarHBondContact O-N 3.24Å; F367-K377 HydrophobicContact CE2-CB 4.36Å; F367-K377 HydrophobicContact CE2-CG 3.92Å; F367-K377 HydrophobicContact CZ-CB 4.2Å; F367-K377 HydrophobicContact CZ-CD 4.32Å; F367-K377 HydrophobicContact CZ-CG 3.84Å; F367-A380 HydrophobicContact CD2-CB 3.66Å; F367-A380 HydrophobicContact CE2-CB 3.83Å; F367-M381 HydrophobicContact CD2-CG 4.23Å; F367-M381 HydrophobicContact CE2-CG 3.97Å
368	A	89.3	Confident	88.2	Confident	0 Å²	0	20.5 Å²	20.5	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-62.6	-41.9	174.2	0	0	0	0	0	111.5	L169 L172 V364 G365 D366 V371 Q372	L169-A368 HydrophobicContact CD1-CB 3.82Å; L172-A368 HydrophobicContact CB-CB 3.8Å; V364-A368 PolarHBondContact O-N 2.93Å; G365-A368 WeakPolarHBondContact O-CA 3.29Å; G365-A368 WeakPolarHBondContact O-CB 3.43Å; G365-A368 PolarHBondContact O-N 3.04Å; D366-A368 PolarHBondContact O-N 2.91Å; A368-V371 PolarHBondContact O-N 3.38Å; A368-Q372 VanDerWaalsContact O-CB 3.24Å; A368-Q372 WeakPolarHBondContact O-CB 3.37Å; A368-Q372 PolarHBondContact O-N 3.33Å
369	I	90.2	Very high	88.3	Confident	4 Å²	4	23.7 Å²	23.7	2%	0.021	14%	0.135	C	C	.	.	H	α-helix	trans	-65.7	-40.5	178.7	-63	163.6	0	0	0	111.4	L173 A176 L180 N322 G365 D366 S373 V430 V435	L173-I369 HydrophobicContact CD1-CB 4.48Å; L173-I369 HydrophobicContact CD1-CD1 4.32Å; L173-I369 HydrophobicContact CD1-CG1 3.4Å; L173-I369 VanDerWaalsContact CD1-CG1 3.4Å; A176-I369 HydrophobicContact CB-CD1 4.1Å; L180-I369 HydrophobicContact CD1-CD1 4.13Å; N322-I369 HydrophobicContact CB-CG2 3.88Å; N322-I369 WeakPolarHBondContact OD1-CD1 3.49Å; N322-I369 VanDerWaalsContact OD1-CG2 3.25Å; N322-I369 WeakPolarHBondContact OD1-CG2 3.1Å; G365-I369 WeakPolarHBondContact O-CG1 3.48Å; G365-I369 PolarHBondContact O-N 3.42Å; D366-I369 PolarHBondContact O-N 3.45Å; I369-S373 WeakPolarHBondContact O-CB 3.1Å; I369-S373 PolarHBondContact O-N 2.96Å; I369-S373 PolarHBondContact O-OG 2.98Å; I369-V430 HydrophobicContact CD1-CG1 4.42Å; I369-V435 HydrophobicContact CD1-CG2 3.55Å; I369-V435 HydrophobicContact CG1-CG2 3.85Å
370	L	91.2	Very high	88.4	Confident	0 Å²	0	23.6 Å²	23.6	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-65.8	-45.2	176	-75.5	169.9	0	0	0	112.4	L315 L323 D366 F367 S373 G374 C375 A380 L383 Q384	L315-L370 HydrophobicContact CD1-CD2 4.49Å; L315-L370 HydrophobicContact CD2-CD2 4.33Å; L323-L370 HydrophobicContact CD1-CD2 3.98Å; L323-L370 HydrophobicContact CD2-CD1 4.06Å; L323-L370 HydrophobicContact CD2-CD2 4.12Å; L323-L370 HydrophobicContact CG-CD2 3.91Å; D366-L370 WeakPolarHBondContact O-CB 3.42Å; D366-L370 WeakPolarHBondContact O-CG 3.37Å; D366-L370 PolarHBondContact O-N 3.14Å; F367-L370 PolarHBondContact O-N 3.43Å; L370-S373 CarbonylContact O-C 3.6Å; L370-S373 PolarHBondContact O-N 3.21Å; L370-G374 PolarHBondContact O-N 3.32Å; L370-C375 HydrophobicContact CB-CB 4.36Å; L370-C375 WeakPolarHBondContact O-CB 3.22Å; L370-C375 PolarHBondContact O-N 3.2Å; L370-A380 HydrophobicContact CB-CB 3.73Å; L370-A380 HydrophobicContact CD1-CB 4.16Å; L370-L383 HydrophobicContact CD1-CB 4.33Å; L370-L383 HydrophobicContact CD2-CD1 4.34Å; L370-Q384 HydrophobicContact CD1-CG 3.64Å
371	V	89.6	Confident	88.5	Confident	24 Å²	24	22.6 Å²	22.6	15%	0.145	13%	0.129	C	C	.	.	H	α-helix	trans	-63.4	-46.3	176.7	170.9	0	0	0	0	110.7	V158 L169 F367 A368 S373 G374 C375 A380	V158-V371 HydrophobicContact CG1-CG1 4.01Å; V158-V371 HydrophobicContact CG1-CG2 3.98Å; L169-V371 HydrophobicContact CD1-CB 4.33Å; L169-V371 HydrophobicContact CD1-CG1 4.2Å; L169-V371 HydrophobicContact CD2-CG1 4.33Å; F367-V371 HydrophobicContact CD2-CG2 4.47Å; F367-V371 HydrophobicContact CE1-CG2 4.14Å; F367-V371 HydrophobicContact CE2-CG2 4.08Å; F367-V371 HydrophobicContact CZ-CG2 3.9Å; F367-V371 WeakPolarHBondContact O-CB 3.41Å; F367-V371 VanDerWaalsContact O-CG2 3.3Å; F367-V371 WeakPolarHBondContact O-CG2 3.32Å; F367-V371 PolarHBondContact O-N 3.24Å; A368-V371 PolarHBondContact O-N 3.38Å; V371-S373 PolarHBondContact O-N 2.95Å; V371-G374 PolarHBondContact O-N 2.92Å; V371-C375 WeakPolarHBondContact CA-O 3.11Å; V371-A380 HydrophobicContact CG2-CB 4.04Å
372	Q	87.6	Confident	88.9	Confident	43 Å²	43	30.1 Å²	30.1	20%	0.201	16%	0.155	C	C	.	.	H	α-helix	trans	-62.2	-29.5	173.7	-179.3	58.1	17.4	0	0	112.7	L169 L173 R316 A368 G374 E438	L169-Q372 HydrophobicContact CD2-CB 4.1Å; L173-Q372 HydrophobicContact CD2-CG 4.42Å; R316-Q372 PolarHBondContact NH1-O 3.19Å; A368-Q372 VanDerWaalsContact O-CB 3.24Å; A368-Q372 WeakPolarHBondContact O-CB 3.37Å; A368-Q372 PolarHBondContact O-N 3.33Å; Q372-G374 VanDerWaalsContact C-N 3.28Å; Q372-G374 PolarHBondContact O-N 3.07Å; Q372-E438 HydrophobicContact CG-CG 4.37Å; Q372-E438 PolarHBondContact NE2-OE1 3.01Å; Q372-E438 PolarHBondContact NE2-OE2 3.12Å
373	S	88.3	Confident	89.1	Confident	2 Å²	2	31.1 Å²	31.1	1%	0.014	16%	0.161	C	C	.	.	T	Hydrogen-bonded Turn	trans	-79.1	-6.4	176.3	-63	0	0	0	0	114	L315 R316 S318 G319 I369 L370 V371	L315-S373 VanDerWaalsContact CD1-CB 3.48Å; R316-S373 WeakPolarHBondContact CG-O 3.43Å; R316-S373 PolarHBondContact N-O 3.29Å; S318-S373 PolarHBondContact OG-OG 2.9Å; G319-S373 WeakPolarHBondContact CA-OG 3.38Å; G319-S373 PolarHBondContact N-OG 3.38Å; G319-S373 VanDerWaalsContact N-OG 3.16Å; I369-S373 WeakPolarHBondContact O-CB 3.1Å; I369-S373 PolarHBondContact O-N 2.96Å; I369-S373 PolarHBondContact O-OG 2.98Å; L370-S373 CarbonylContact O-C 3.6Å; L370-S373 PolarHBondContact O-N 3.21Å; V371-S373 PolarHBondContact O-N 2.95Å
374	G	88.2	Confident	89.2	Confident	56 Å²	56	31 Å²	31	58%	0.577	16%	0.16	S	C	*	.	T	Hydrogen-bonded Turn	trans	117.3	3.9	172.9	0	0	0	0	0	115.9	L370 V371 Q372	L370-G374 PolarHBondContact O-N 3.32Å; V371-G374 PolarHBondContact O-N 2.92Å; Q372-G374 VanDerWaalsContact C-N 3.28Å; Q372-G374 PolarHBondContact O-N 3.07Å
375	C	87.9	Confident	89.3	Confident	7 Å²	7	35.4 Å²	35.4	5%	0.047	18%	0.183	C	C	.	.			trans	-74.8	141	174.6	-70.2	0	0	0	0	112.3	L315 L370 V371 Q379 A380 L383	L315-C375 VanDerWaalsContact CD1-SG 3.57Å; L370-C375 HydrophobicContact CB-CB 4.36Å; L370-C375 WeakPolarHBondContact O-CB 3.22Å; L370-C375 PolarHBondContact O-N 3.2Å; V371-C375 WeakPolarHBondContact CA-O 3.11Å; C375-Q379 HydrophobicContact CB-CB 3.98Å; C375-A380 HydrophobicContact CB-CB 4.01Å; C375-L383 VanDerWaalsContact SG-CD1 3.53Å
376	S	88	Confident	89.5	Confident	58 Å²	58	40.2 Å²	40.2	41%	0.406	21%	0.209	S	C	.	.			trans	-65.9	156.8	155.8	62	0	0	0	0	110.7	K378 Q379 A380	S376-K378 PolarHBondContact O-N 3.37Å; S376-K378 VanDerWaalsContact O-N 3.16Å; S376-Q379 WeakPolarHBondContact O-CA 3.07Å; S376-Q379 WeakPolarHBondContact O-CB 3.49Å; S376-Q379 PolarHBondContact O-N 2.85Å; S376-Q379 VanDerWaalsContact OG-CD 3.27Å; S376-Q379 WeakPolarHBondContact OG-CG 3.45Å; S376-Q379 PolarHBondContact OG-N 3.42Å; S376-Q379 PolarHBondContact OG-OE1 3.46Å; S376-A380 PolarHBondContact O-N 2.9Å
377	K	86.6	Confident	89.6	Confident	23 Å²	23	40.2 Å²	40.2	10%	0.1	21%	0.208	C	C	.	.	H	α-helix	trans	-46	-48	175.9	173.3	168.6	-178	178.1	0	112.4	L153 F154 I156 V158 E159 F367 Q379 A380 M381	L153-K377 VanDerWaalsContact O-CE 3.27Å; L153-K377 WeakPolarHBondContact O-CE 3.41Å; L153-K377 PolarHBondContact O-NZ 2.89Å; F154-K377 PolarHBondContact O-NZ 3.49Å; I156-K377 PolarHBondContact O-NZ 3.4Å; V158-K377 HydrophobicContact CB-CD 4.49Å; V158-K377 HydrophobicContact CG1-CB 4.49Å; E159-K377 HydrophobicContact CG-CB 4.17Å; E159-K377 HydrophobicContact CG-CD 3.88Å; F367-K377 HydrophobicContact CE2-CB 4.36Å; F367-K377 HydrophobicContact CE2-CG 3.92Å; F367-K377 HydrophobicContact CZ-CB 4.2Å; F367-K377 HydrophobicContact CZ-CD 4.32Å; F367-K377 HydrophobicContact CZ-CG 3.84Å; K377-Q379 VanDerWaalsContact C-N 3.33Å; K377-Q379 PolarHBondContact O-N 3.19Å; K377-A380 PolarHBondContact O-N 2.83Å; K377-M381 HydrophobicContact CD-SD 4.42Å; K377-M381 HydrophobicContact CG-CG 4.49Å; K377-M381 HydrophobicContact CG-SD 3.79Å; K377-M381 VanDerWaalsContact O-CG 3.3Å; K377-M381 WeakPolarHBondContact O-CG 3.32Å; K377-M381 PolarHBondContact O-N 2.87Å
378	K	88	Confident	89.7	Confident	147 Å²	147	40.6 Å²	40.6	64%	0.639	21%	0.212	S	C	*	.	H	α-helix	trans	-66	-29.8	179	-65.9	178.5	-175.8	170.4	0	113.9	S376 R382	S376-K378 PolarHBondContact O-N 3.37Å; S376-K378 VanDerWaalsContact O-N 3.16Å; K378-R382 WeakPolarHBondContact O-CB 3.25Å; K378-R382 WeakPolarHBondContact O-CD 3.41Å; K378-R382 WeakPolarHBondContact O-CG 3.38Å; K378-R382 PolarHBondContact O-N 3.02Å
379	Q	90.1	Very high	89.9	Confident	67 Å²	67	44.7 Å²	44.7	31%	0.313	24%	0.237	S	C	.	.	H	α-helix	trans	-76	-44.3	174.3	-75.6	163.6	-42	0	0	111.1	C375 S376 K377 R382 L383	C375-Q379 HydrophobicContact CB-CB 3.98Å; S376-Q379 WeakPolarHBondContact O-CA 3.07Å; S376-Q379 WeakPolarHBondContact O-CB 3.49Å; S376-Q379 PolarHBondContact O-N 2.85Å; S376-Q379 VanDerWaalsContact OG-CD 3.27Å; S376-Q379 WeakPolarHBondContact OG-CG 3.45Å; S376-Q379 PolarHBondContact OG-N 3.42Å; S376-Q379 PolarHBondContact OG-OE1 3.46Å; K377-Q379 VanDerWaalsContact C-N 3.33Å; K377-Q379 PolarHBondContact O-N 3.19Å; Q379-R382 PolarHBondContact O-N 3.46Å; Q379-L383 VanDerWaalsContact O-CG 3.29Å; Q379-L383 WeakPolarHBondContact O-CG 3.47Å; Q379-L383 PolarHBondContact O-N 3.05Å
380	A	90	Very high	90	Very high	0 Å²	0	44.7 Å²	44.7	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-57	-53.6	177.2	0	0	0	0	0	111	F367 L370 V371 C375 S376 K377 R382 L383 Q384	F367-A380 HydrophobicContact CD2-CB 3.66Å; F367-A380 HydrophobicContact CE2-CB 3.83Å; L370-A380 HydrophobicContact CB-CB 3.73Å; L370-A380 HydrophobicContact CD1-CB 4.16Å; V371-A380 HydrophobicContact CG2-CB 4.04Å; C375-A380 HydrophobicContact CB-CB 4.01Å; S376-A380 PolarHBondContact O-N 2.9Å; K377-A380 PolarHBondContact O-N 2.83Å; A380-R382 PolarHBondContact O-N 3.41Å; A380-R382 VanDerWaalsContact O-N 3.16Å; A380-L383 PolarHBondContact O-N 3.15Å; A380-Q384 PolarHBondContact O-N 2.91Å; A380-Q384 PolarHBondContact O-OE1 2.89Å
381	M	89.1	Confident	90.1	Very high	12 Å²	12	44.7 Å²	44.7	6%	0.059	24%	0.238	C	C	.	.	H	α-helix	trans	-59.3	-29.7	177.5	-64.2	173	77.9	0	0	113.9	F150 L153 F154 F367 K377 L385	F150-M381 HydrophobicContact CD1-CE 4.21Å; F150-M381 HydrophobicContact CD2-CB 4.31Å; F150-M381 HydrophobicContact CD2-CE 3.92Å; F150-M381 HydrophobicContact CE1-CE 4.04Å; F150-M381 HydrophobicContact CE2-CB 3.97Å; F150-M381 HydrophobicContact CE2-CE 3.74Å; F150-M381 HydrophobicContact CG-CE 4.15Å; F150-M381 HydrophobicContact CZ-CE 3.8Å; L153-M381 HydrophobicContact CB-CE 4.07Å; L153-M381 HydrophobicContact CB-CG 4.31Å; L153-M381 HydrophobicContact CD1-CG 4.42Å; F154-M381 HydrophobicContact CB-CE 4.4Å; F367-M381 HydrophobicContact CD2-CG 4.23Å; F367-M381 HydrophobicContact CE2-CG 3.97Å; K377-M381 HydrophobicContact CD-SD 4.42Å; K377-M381 HydrophobicContact CG-CG 4.49Å; K377-M381 HydrophobicContact CG-SD 3.79Å; K377-M381 VanDerWaalsContact O-CG 3.3Å; K377-M381 WeakPolarHBondContact O-CG 3.32Å; K377-M381 PolarHBondContact O-N 2.87Å; M381-L385 WeakPolarHBondContact O-CB 3.27Å; M381-L385 PolarHBondContact O-N 2.92Å
382	R	91.3	Very high	90.4	Very high	168 Å²	168	46.7 Å²	46.7	63%	0.634	25%	0.247	S	C	*	.	H	α-helix	trans	-77.6	-30.2	175.4	-80.6	176.8	-179.8	-168.7	0.6	112.8	E309 K378 Q379 A380 L386	E309-R382 IonicContact OE1-NH1 3.69Å; K378-R382 WeakPolarHBondContact O-CB 3.25Å; K378-R382 WeakPolarHBondContact O-CD 3.41Å; K378-R382 WeakPolarHBondContact O-CG 3.38Å; K378-R382 PolarHBondContact O-N 3.02Å; Q379-R382 PolarHBondContact O-N 3.46Å; A380-R382 PolarHBondContact O-N 3.41Å; A380-R382 VanDerWaalsContact O-N 3.16Å; R382-L386 PolarHBondContact O-N 3.49Å
383	L	92	Very high	90.7	Very high	30 Å²	30	46.6 Å²	46.6	16%	0.157	25%	0.254	C	S	.	.	H	α-helix	trans	-79.9	-34.6	179.9	-70.4	165.6	0	0	0	111.2	L313 L323 L370 C375 Q379 A380 L386	L313-L383 HydrophobicContact CD2-CD1 4Å; L323-L383 HydrophobicContact CD1-CB 4.04Å; L323-L383 HydrophobicContact CD1-CD1 4.27Å; L323-L383 HydrophobicContact CD1-CD2 4.15Å; L323-L383 HydrophobicContact CD1-CG 4.38Å; L323-L383 HydrophobicContact CD2-CB 3.82Å; L370-L383 HydrophobicContact CD1-CB 4.33Å; L370-L383 HydrophobicContact CD2-CD1 4.34Å; C375-L383 VanDerWaalsContact SG-CD1 3.53Å; Q379-L383 VanDerWaalsContact O-CG 3.29Å; Q379-L383 WeakPolarHBondContact O-CG 3.47Å; Q379-L383 PolarHBondContact O-N 3.05Å; A380-L383 PolarHBondContact O-N 3.15Å; L383-L386 VanDerWaalsContact O-CB 3.25Å; L383-L386 WeakPolarHBondContact O-CB 3.42Å; L383-L386 PolarHBondContact O-N 2.84Å; L383-L386 VanDerWaalsContact O-N 3.17Å
384	Q	90.3	Very high	90.8	Very high	2 Å²	2	46.5 Å²	46.5	1%	0.009	25%	0.253	C	S	.	.	H	α-helix	trans	-65.5	-44.8	169.5	-70.5	173.4	-66.4	0	0	111.7	E363 L370 A380 L386 T387	E363-Q384 PolarHBondContact O-NE2 3.44Å; E363-Q384 VanDerWaalsContact OE2-CB 3.25Å; E363-Q384 WeakPolarHBondContact OE2-CB 3.47Å; E363-Q384 WeakPolarHBondContact OE2-CG 3.13Å; E363-Q384 PolarHBondContact OE2-NE2 3.29Å; L370-Q384 HydrophobicContact CD1-CG 3.64Å; A380-Q384 PolarHBondContact O-N 2.91Å; A380-Q384 PolarHBondContact O-OE1 2.89Å; Q384-L386 PolarHBondContact O-N 3.45Å; Q384-T387 PolarHBondContact O-N 2.85Å; Q384-T387 PolarHBondContact O-OG1 3.48Å
385	L	90	Very high	91	Very high	94 Å²	94	43.9 Å²	43.9	49%	0.492	23%	0.226	S	C	.	.	H	α-helix	trans	-60.2	-13.5	172.7	-170.5	59.7	0	0	0	113.7	M381 A388	M381-L385 WeakPolarHBondContact O-CB 3.27Å; M381-L385 PolarHBondContact O-N 2.92Å; L385-A388 WeakPolarHBondContact O-CB 3.24Å
386	L	92	Very high	91.2	Very high	103 Å²	103	44.8 Å²	44.8	54%	0.539	23%	0.234	S	C	.	.	H	α-helix	trans	-84.3	-26.8	172.2	-171.5	63.8	0	0	0	113	R382 L383 Q384 A388 V389	R382-L386 PolarHBondContact O-N 3.49Å; L383-L386 VanDerWaalsContact O-CB 3.25Å; L383-L386 WeakPolarHBondContact O-CB 3.42Å; L383-L386 PolarHBondContact O-N 2.84Å; L383-L386 VanDerWaalsContact O-N 3.17Å; Q384-L386 PolarHBondContact O-N 3.45Å; L386-A388 VanDerWaalsContact C-N 3.28Å; L386-A388 PolarHBondContact O-N 2.89Å; L386-V389 HydrophobicContact CD1-CG2 4.24Å; L386-V389 VanDerWaalsContact O-CB 3.32Å; L386-V389 WeakPolarHBondContact O-CB 3.22Å; L386-V389 VanDerWaalsContact O-CG2 3.32Å; L386-V389 WeakPolarHBondContact O-CG2 3.4Å; L386-V389 PolarHBondContact O-N 3.45Å
387	T	91.8	Very high	91.2	Very high	3 Å²	3	44.5 Å²	44.5	2%	0.018	23%	0.232	C	C	.	.	H	α-helix	trans	-74	-21.4	177.3	61.8	0	0	0	0	112.5	L323 D326 L327 Q384 V389 G390	L323-T387 HydrophobicContact CD2-CG2 3.89Å; D326-T387 HydrophobicContact CB-CG2 4.14Å; D326-T387 VanDerWaalsContact CG-CB 3.49Å; D326-T387 WeakPolarHBondContact OD1-CB 3.37Å; D326-T387 PolarHBondContact OD1-OG1 3.32Å; D326-T387 WeakPolarHBondContact OD2-CB 3.41Å; D326-T387 WeakPolarHBondContact OD2-CG2 3.42Å; D326-T387 PolarHBondContact OD2-OG1 3.21Å; L327-T387 HydrophobicContact CB-CG2 3.96Å; Q384-T387 PolarHBondContact O-N 2.85Å; Q384-T387 PolarHBondContact O-OG1 3.48Å; T387-V389 PolarHBondContact O-N 3.29Å; T387-G390 WeakPolarHBondContact O-CA 3.26Å; T387-G390 PolarHBondContact O-N 2.95Å
388	A	92.2	Very high	91.2	Very high	10 Å²	10	43.4 Å²	43.4	8%	0.083	23%	0.227	C	C	.	.	H	α-helix	trans	-49.7	-24.8	163.1	0	0	0	0	0	114.6	S146 L385 L386 G390 A391 L392	S146-A388 VanDerWaalsContact CB-CB 3.45Å; L385-A388 WeakPolarHBondContact O-CB 3.24Å; L386-A388 VanDerWaalsContact C-N 3.28Å; L386-A388 PolarHBondContact O-N 2.89Å; A388-G390 VanDerWaalsContact C-N 3.26Å; A388-G390 PolarHBondContact O-N 3.49Å; A388-A391 PolarHBondContact O-N 2.73Å; A388-L392 WeakPolarHBondContact O-CG 3.38Å; A388-L392 PolarHBondContact O-N 3.1Å
389	V	93.9	Very high	91.2	Very high	85 Å²	85	36.7 Å²	36.7	52%	0.515	20%	0.198	S	C	.	.	H	α-helix	trans	-64.6	-33.5	172.7	177.7	0	0	0	0	111.2	L386 T387 A393	L386-V389 HydrophobicContact CD1-CG2 4.24Å; L386-V389 VanDerWaalsContact O-CB 3.32Å; L386-V389 WeakPolarHBondContact O-CB 3.22Å; L386-V389 VanDerWaalsContact O-CG2 3.32Å; L386-V389 WeakPolarHBondContact O-CG2 3.4Å; L386-V389 PolarHBondContact O-N 3.45Å; T387-V389 PolarHBondContact O-N 3.29Å; V389-A393 VanDerWaalsContact O-CB 3.28Å; V389-A393 WeakPolarHBondContact O-CB 3.38Å; V389-A393 PolarHBondContact O-N 2.69Å
390	G	92.7	Very high	91.1	Very high	4 Å²	4	39.3 Å²	39.3	4%	0.041	21%	0.214	C	C	.	.	H	α-helix	trans	-58.2	-54	170.6	0	0	0	0	0	111.1	F331 T387 A388 L392 A393 G394	F331-G390 WeakPolarHBondContact CA-O 3.42Å; F331-G390 WeakPolarHBondContact CD2-O 3.36Å; T387-G390 WeakPolarHBondContact O-CA 3.26Å; T387-G390 PolarHBondContact O-N 2.95Å; A388-G390 VanDerWaalsContact C-N 3.26Å; A388-G390 PolarHBondContact O-N 3.49Å; G390-L392 PolarHBondContact O-N 3.16Å; G390-A393 WeakPolarHBondContact O-CB 3.5Å; G390-A393 PolarHBondContact O-N 3.32Å; G390-A393 VanDerWaalsContact O-N 3.13Å; G390-G394 PolarHBondContact O-N 2.95Å
391	A	93.7	Very high	90.4	Very high	0 Å²	0	40.9 Å²	40.9	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-60.7	-44.8	179.2	0	0	0	0	0	113	T142 N330 G334 A388 A393 G394 T395	T142-A391 VanDerWaalsContact CG2-C 3.47Å; T142-A391 HydrophobicContact CG2-CB 3.58Å; N330-A391 HydrophobicContact CB-CB 4.08Å; N330-A391 WeakPolarHBondContact O-CA 3.43Å; N330-A391 WeakPolarHBondContact O-CB 3.49Å; N330-A391 PolarHBondContact O-N 3.28Å; N330-A391 WeakPolarHBondContact OD1-CB 3.25Å; G334-A391 WeakPolarHBondContact CA-O 3.32Å; A388-A391 PolarHBondContact O-N 2.73Å; A391-A393 VanDerWaalsContact C-N 3.3Å; A391-A393 PolarHBondContact O-N 3.41Å; A391-G394 PolarHBondContact O-N 2.79Å; A391-T395 PolarHBondContact O-N 3.24Å; A391-T395 PolarHBondContact O-OG1 3.41Å
392	L	95.3	Very high	89	Confident	66 Å²	66	48.8 Å²	48.8	35%	0.346	26%	0.26	S	S	.	.	H	α-helix	trans	-61.7	-37.5	175.3	-69.6	170	0	0	0	112.6	L139 T142 V143 A388 G390 A396	L139-L392 HydrophobicContact CD2-CD2 4.08Å; T142-L392 HydrophobicContact CG2-CD2 3.83Å; T142-L392 HydrophobicContact CG2-CG 4.15Å; V143-L392 HydrophobicContact CG2-CD2 4.06Å; A388-L392 WeakPolarHBondContact O-CG 3.38Å; A388-L392 PolarHBondContact O-N 3.1Å; G390-L392 PolarHBondContact O-N 3.16Å; L392-A396 WeakPolarHBondContact O-CB 3.32Å; L392-A396 PolarHBondContact O-N 2.82Å
393	A	93	Very high	87.3	Confident	42 Å²	42	44 Å²	44	35%	0.347	26%	0.263	S	S	.	.	H	α-helix	trans	-68.1	-42.8	174.8	0	0	0	0	0	112	F331 V389 G390 A391 A396 C397	F331-A393 HydrophobicContact CD2-CB 4.21Å; F331-A393 HydrophobicContact CE2-CB 4.37Å; V389-A393 VanDerWaalsContact O-CB 3.28Å; V389-A393 WeakPolarHBondContact O-CB 3.38Å; V389-A393 PolarHBondContact O-N 2.69Å; G390-A393 WeakPolarHBondContact O-CB 3.5Å; G390-A393 PolarHBondContact O-N 3.32Å; G390-A393 VanDerWaalsContact O-N 3.13Å; A391-A393 VanDerWaalsContact C-N 3.3Å; A391-A393 PolarHBondContact O-N 3.41Å; A393-A396 PolarHBondContact O-N 3.05Å; A393-C397 WeakPolarHBondContact O-CB 3.38Å; A393-C397 PolarHBondContact O-N 3.2Å; A393-C397 PolarHBondContact O-SG 3.41Å; A393-C397 VanDerWaalsContact O-SG 3.33Å
394	G	90.3	Very high	85.4	Confident	0 Å²	0	42.7 Å²	42.7	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-60	-48.1	176.2	0	0	0	0	0	112.1	F331 G334 L335 G390 A391 A396 C397 A398	F331-G394 WeakPolarHBondContact O-CA 3.21Å; G334-G394 VanDerWaalsContact C-C 3.47Å; L335-G394 WeakPolarHBondContact CD2-O 3.16Å; G390-G394 PolarHBondContact O-N 2.95Å; A391-G394 PolarHBondContact O-N 2.79Å; G394-A396 PolarHBondContact O-N 3.03Å; G394-C397 WeakPolarHBondContact O-CB 3.29Å; G394-C397 PolarHBondContact O-N 3.09Å; G394-A398 PolarHBondContact O-N 3.36Å
395	T	92.5	Very high	83.5	Confident	0 Å²	0	44.3 Å²	44.3	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-59.4	-46.4	175.6	-57.7	0	0	0	0	111.4	A138 L139 T142 G334 A391 C397 A398 L399	A138-T395 HydrophobicContact CB-CG2 3.82Å; L139-T395 HydrophobicContact CD2-CG2 4Å; T142-T395 WeakPolarHBondContact OG1-CB 3.43Å; T142-T395 WeakPolarHBondContact OG1-CG2 3.21Å; T142-T395 PolarHBondContact OG1-OG1 3.41Å; G334-T395 VanDerWaalsContact C-N 3.27Å; G334-T395 WeakPolarHBondContact CA-OG1 3.35Å; G334-T395 WeakPolarHBondContact O-CA 3.48Å; G334-T395 PolarHBondContact O-N 3.04Å; G334-T395 PolarHBondContact O-OG1 3.09Å; A391-T395 PolarHBondContact O-N 3.24Å; A391-T395 PolarHBondContact O-OG1 3.41Å; T395-C397 PolarHBondContact O-N 2.99Å; T395-A398 PolarHBondContact O-N 3.39Å; T395-L399 HydrophobicContact CG2-CD1 3.89Å; T395-L399 HydrophobicContact CG2-CG 4.41Å; T395-L399 WeakPolarHBondContact O-CB 3.18Å; T395-L399 VanDerWaalsContact O-CG 3.23Å; T395-L399 WeakPolarHBondContact O-CG 3.28Å; T395-L399 PolarHBondContact O-N 2.96Å
396	A	92.3	Very high	81.6	Confident	26 Å²	26	41.8 Å²	41.8	22%	0.215	26%	0.259	C	S	.	.	H	α-helix	trans	-61.1	-42.3	176.2	0	0	0	0	0	112	L392 A393 G394 L399 L400	L392-A396 WeakPolarHBondContact O-CB 3.32Å; L392-A396 PolarHBondContact O-N 2.82Å; A393-A396 PolarHBondContact O-N 3.05Å; G394-A396 PolarHBondContact O-N 3.03Å; A396-L399 PolarHBondContact O-N 3.04Å; A396-L400 VanDerWaalsContact O-CB 3.29Å; A396-L400 WeakPolarHBondContact O-CB 3.44Å; A396-L400 WeakPolarHBondContact O-CD1 3.3Å; A396-L400 WeakPolarHBondContact O-CG 3.19Å; A396-L400 PolarHBondContact O-N 3.42Å
397	C	88.6	Confident	79.6	Confident	53 Å²	53	37 Å²	37	36%	0.358	23%	0.234	S	C	.	.	H	α-helix	trans	-59.8	-48.4	175.9	-76.7	0	0	0	0	112.3	L335 A393 G394 T395 L399 L400 T401	L335-C397 HydrophobicContact CD2-CB 3.95Å; A393-C397 WeakPolarHBondContact O-CB 3.38Å; A393-C397 PolarHBondContact O-N 3.2Å; A393-C397 PolarHBondContact O-SG 3.41Å; A393-C397 VanDerWaalsContact O-SG 3.33Å; G394-C397 WeakPolarHBondContact O-CB 3.29Å; G394-C397 PolarHBondContact O-N 3.09Å; T395-C397 PolarHBondContact O-N 2.99Å; C397-L399 PolarHBondContact O-N 2.97Å; C397-L400 PolarHBondContact O-N 3.23Å; C397-T401 VanDerWaalsContact O-CG2 3.26Å; C397-T401 WeakPolarHBondContact O-CG2 3.43Å; C397-T401 PolarHBondContact O-N 3.03Å
398	A	85.6	Confident	77.6	Confident	0 Å²	0	39.9 Å²	39.9	0%	0	26%	0.255	C	S	.	.	H	α-helix	trans	-62	-41.1	177.8	0	0	0	0	0	112.4	L335 G394 T395 T401	L335-A398 HydrophobicContact CD2-CB 4.21Å; L335-A398 WeakPolarHBondContact O-CB 3.45Å; G394-A398 PolarHBondContact O-N 3.36Å; T395-A398 PolarHBondContact O-N 3.39Å; A398-T401 PolarHBondContact O-OG1 2.72Å
399	L	88.7	Confident	75.6	Confident	6 Å²	6	42.8 Å²	42.8	3%	0.031	27%	0.266	C	S	.	.	H	α-helix	trans	-71.6	-37.5	179.4	-67.2	173.7	0	0	0	113.7	L134 W135 A138 R342 T395 A396 C397 T401	L134-L399 HydrophobicContact CD1-CD2 4.21Å; L134-L399 HydrophobicContact CD2-CD2 4.08Å; L134-L399 HydrophobicContact CG-CD2 3.86Å; W135-L399 HydrophobicContact CB-CD1 4.46Å; W135-L399 HydrophobicContact CD2-CB 4.24Å; W135-L399 HydrophobicContact CD2-CD1 3.68Å; W135-L399 HydrophobicContact CE3-CD1 3.89Å; W135-L399 HydrophobicContact CG-CD1 3.93Å; W135-L399 HydrophobicContact CH2-CB 4.19Å; W135-L399 HydrophobicContact CZ2-CB 3.64Å; W135-L399 HydrophobicContact CZ2-CD1 4.48Å; W135-L399 HydrophobicContact CZ3-CD1 4.37Å; A138-L399 HydrophobicContact CB-CD1 3.92Å; A138-L399 HydrophobicContact CB-CD2 4.17Å; A138-L399 HydrophobicContact CB-CG 4.43Å; R342-L399 PolarHBondContact NH1-O 3.01Å; T395-L399 HydrophobicContact CG2-CD1 3.89Å; T395-L399 HydrophobicContact CG2-CG 4.41Å; T395-L399 WeakPolarHBondContact O-CB 3.18Å; T395-L399 VanDerWaalsContact O-CG 3.23Å; T395-L399 WeakPolarHBondContact O-CG 3.28Å; T395-L399 PolarHBondContact O-N 2.96Å; A396-L399 PolarHBondContact O-N 3.04Å; C397-L399 PolarHBondContact O-N 2.97Å; L399-T401 VanDerWaalsContact C-N 3.31Å; L399-T401 PolarHBondContact O-N 3.36Å
400	L	87.3	Confident	73.4	Confident	122 Å²	122	39.6 Å²	39.6	64%	0.639	25%	0.246	S	C	*	.	H	α-helix	trans	-69.2	-26.8	179	-75.8	169.1	0	0	0	113.1	W135 A396 C397 E402	W135-L400 HydrophobicContact CH2-CD2 3.87Å; W135-L400 HydrophobicContact CH2-CG 3.84Å; W135-L400 HydrophobicContact CZ2-CD2 3.89Å; W135-L400 HydrophobicContact CZ2-CG 4.03Å; A396-L400 VanDerWaalsContact O-CB 3.29Å; A396-L400 WeakPolarHBondContact O-CB 3.44Å; A396-L400 WeakPolarHBondContact O-CD1 3.3Å; A396-L400 WeakPolarHBondContact O-CG 3.19Å; A396-L400 PolarHBondContact O-N 3.42Å; C397-L400 PolarHBondContact O-N 3.23Å; L400-E402 PolarHBondContact O-N 3.47Å
401	T	75.5	Confident	71.2	Confident	33 Å²	33	41.4 Å²	41.4	20%	0.202	26%	0.261	C	S	.	.	S	Bend	trans	-73.9	122.4	180	60.9	0	0	0	0	111.2	R342 C397 A398 L399 G404 A405 V406	R342-T401 VanDerWaalsContact CZ-O 3.23Å; R342-T401 PolarHBondContact NH1-O 3.31Å; R342-T401 PolarHBondContact NH2-O 2.9Å; C397-T401 VanDerWaalsContact O-CG2 3.26Å; C397-T401 WeakPolarHBondContact O-CG2 3.43Å; C397-T401 PolarHBondContact O-N 3.03Å; A398-T401 PolarHBondContact O-OG1 2.72Å; L399-T401 VanDerWaalsContact C-N 3.31Å; L399-T401 PolarHBondContact O-N 3.36Å; T401-G404 WeakPolarHBondContact O-CA 3.23Å; T401-G404 PolarHBondContact O-N 2.84Å; T401-G404 VanDerWaalsContact OG1-C 3.26Å; T401-G404 WeakPolarHBondContact OG1-CA 3.35Å; T401-A405 PolarHBondContact OG1-N 2.78Å; T401-V406 HydrophobicContact CG2-CB 3.78Å; T401-V406 HydrophobicContact CG2-CG2 3.42Å; T401-V406 VanDerWaalsContact CG2-CG2 3.42Å; T401-V406 PolarHBondContact OG1-N 2.86Å
402	E	59.4	Low	68.7	Low	177 Å²	177	42.3 Å²	42.3	83%	0.827	27%	0.27	S	S	*	.	G	3₁₀ helix	trans	-61.5	142.3	173.4	-67.6	-173.5	171.4	0	0	110.2	L400 G404 A405	L400-E402 PolarHBondContact O-N 3.47Å; E402-G404 PolarHBondContact O-N 3.34Å; E402-A405 PolarHBondContact O-N 3.47Å
403	G	57.1	Low	66	Low	68 Å²	68	41.6 Å²	41.6	70%	0.701	28%	0.279	S	S	*	.	G	3₁₀ helix	trans	65.9	-3.7	-167.3	0	0	0	0	0	115.1
404	G	52.4	Low	63.5	Low	2 Å²	2	43.4 Å²	43.4	2%	0.021	29%	0.294	C	S	.	.	G	3₁₀ helix	trans	69.1	20.4	-169.4	0	0	0	0	0	112.7	R342 T401 E402 V406 G407 S408	R342-G404 VanDerWaalsContact CD-CA 3.47Å; T401-G404 WeakPolarHBondContact O-CA 3.23Å; T401-G404 PolarHBondContact O-N 2.84Å; T401-G404 VanDerWaalsContact OG1-C 3.26Å; T401-G404 WeakPolarHBondContact OG1-CA 3.35Å; E402-G404 PolarHBondContact O-N 3.34Å; G404-V406 VanDerWaalsContact C-N 3.31Å; G404-V406 PolarHBondContact O-N 3.13Å; G404-V406 VanDerWaalsContact O-N 3.13Å; G404-G407 CarbonylContact O-C 3.57Å; G404-G407 WeakPolarHBondContact O-CA 3.37Å; G404-G407 PolarHBondContact O-N 3.44Å; G404-S408 WeakPolarHBondContact O-CB 3.43Å; G404-S408 PolarHBondContact O-N 3.45Å
405	A	49.5	Very low	61.6	Low	36 Å²	36	44.3 Å²	44.3	30%	0.298	30%	0.303	S	S	.	.	H	α-helix	trans	-47.7	-47.6	-166.2	0	0	0	0	0	113.3	T401 E402 G407 S408 E409	T401-A405 PolarHBondContact OG1-N 2.78Å; E402-A405 PolarHBondContact O-N 3.47Å; A405-G407 PolarHBondContact O-N 3.01Å; A405-S408 PolarHBondContact O-N 3.01Å; A405-E409 WeakPolarHBondContact O-CA 3.39Å; A405-E409 WeakPolarHBondContact O-CB 3.44Å; A405-E409 WeakPolarHBondContact O-CG 3.48Å; A405-E409 PolarHBondContact O-N 3.38Å
406	V	50.7	Low	59.8	Low	41 Å²	41	46 Å²	46	25%	0.248	31%	0.314	C	S	.	.	H	α-helix	trans	-62.4	-43.1	179.1	172.5	0	0	0	0	111.9	L335 T401 G404 I410 P416	L335-V406 HydrophobicContact CD2-CG1 3.84Å; T401-V406 HydrophobicContact CG2-CB 3.78Å; T401-V406 HydrophobicContact CG2-CG2 3.42Å; T401-V406 VanDerWaalsContact CG2-CG2 3.42Å; T401-V406 PolarHBondContact OG1-N 2.86Å; G404-V406 VanDerWaalsContact C-N 3.31Å; G404-V406 PolarHBondContact O-N 3.13Å; G404-V406 VanDerWaalsContact O-N 3.13Å; V406-I410 HydrophobicContact CG1-CD1 3.82Å; V406-I410 VanDerWaalsContact O-CB 3.28Å; V406-I410 WeakPolarHBondContact O-CB 3.33Å; V406-I410 VanDerWaalsContact O-CD1 3.3Å; V406-I410 WeakPolarHBondContact O-CD1 3.4Å; V406-I410 WeakPolarHBondContact O-CG1 3.31Å; V406-I410 PolarHBondContact O-N 2.68Å; V406-P416 HydrophobicContact CG1-CG 3.84Å
407	G	50.1	Low	58.5	Low	2 Å²	2	46.1 Å²	46.1	2%	0.021	32%	0.318	C	S	.	.	H	α-helix	trans	-72.3	-39.9	178.4	0	0	0	0	0	113.8	G404 A405 A411	G404-G407 CarbonylContact O-C 3.57Å; G404-G407 WeakPolarHBondContact O-CA 3.37Å; G404-G407 PolarHBondContact O-N 3.44Å; A405-G407 PolarHBondContact O-N 3.01Å; G407-A411 VanDerWaalsContact O-CB 3.3Å; G407-A411 WeakPolarHBondContact O-CB 3.45Å; G407-A411 PolarHBondContact O-N 3.27Å
408	S	49.2	Very low	58.1	Low	65 Å²	65	48.8 Å²	48.8	46%	0.455	32%	0.32	S	S	.	.	H	α-helix	trans	-78.5	-19.5	179.6	-172	0	0	0	0	113.5	G404 A405 A411 G412	G404-S408 WeakPolarHBondContact O-CB 3.43Å; G404-S408 PolarHBondContact O-N 3.45Å; A405-S408 PolarHBondContact O-N 3.01Å; S408-A411 CarbonylContact O-C 3.56Å; S408-G412 WeakPolarHBondContact O-CA 3.46Å; S408-G412 PolarHBondContact O-N 2.94Å; S408-G412 VanDerWaalsContact O-N 3.09Å
409	E	49.2	Very low	57.8	Low	71 Å²	71	49.3 Å²	49.3	33%	0.332	32%	0.324	S	S	.	.	H	α-helix	trans	-92.1	-30.2	173.4	-67.1	178.6	-180	0	0	111.1	A405 A411 G412 G413 A414 G415	A405-E409 WeakPolarHBondContact O-CA 3.39Å; A405-E409 WeakPolarHBondContact O-CB 3.44Å; A405-E409 WeakPolarHBondContact O-CG 3.48Å; A405-E409 PolarHBondContact O-N 3.38Å; E409-A411 VanDerWaalsContact C-N 3.34Å; E409-G412 CarbonylContact O-C 3Å; E409-G412 PolarHBondContact O-N 2.94Å; E409-G412 VanDerWaalsContact O-N 3.14Å; E409-G413 PolarHBondContact O-N 2.97Å; E409-A414 HydrophobicContact CB-CB 4.42Å; E409-A414 HydrophobicContact CG-CB 4.06Å; E409-A414 PolarHBondContact O-N 3.2Å; E409-G415 CarbonylContact C-O 3.59Å; E409-G415 WeakPolarHBondContact CB-O 3.36Å; E409-G415 WeakPolarHBondContact OE2-CA 3.29Å
410	I	49	Very low	57.6	Low	17 Å²	17	49.6 Å²	49.6	9%	0.087	33%	0.325	C	S	.	.	H	α-helix	trans	-63.3	-43	164.6	-72.5	168.6	0	0	0	109.9	L335 V406 G412 G415 P416 L420	L335-I410 HydrophobicContact CB-CD1 4.3Å; L335-I410 HydrophobicContact CD1-CD1 3.56Å; L335-I410 HydrophobicContact CD2-CD1 4.1Å; L335-I410 HydrophobicContact CG-CD1 4.2Å; V406-I410 HydrophobicContact CG1-CD1 3.82Å; V406-I410 VanDerWaalsContact O-CB 3.28Å; V406-I410 WeakPolarHBondContact O-CB 3.33Å; V406-I410 VanDerWaalsContact O-CD1 3.3Å; V406-I410 WeakPolarHBondContact O-CD1 3.4Å; V406-I410 WeakPolarHBondContact O-CG1 3.31Å; V406-I410 PolarHBondContact O-N 2.68Å; I410-G412 VanDerWaalsContact C-N 3.25Å; I410-G412 PolarHBondContact O-N 3.02Å; I410-G415 PolarHBondContact N-O 2.9Å; I410-P416 HydrophobicContact CD1-CG 3.98Å; I410-P416 HydrophobicContact CG1-CG 3.91Å; I410-L420 HydrophobicContact CG2-CD1 3.99Å; I410-L420 HydrophobicContact CG2-CG 4.26Å
411	A	46.6	Very low	57.7	Low	43 Å²	43	43.8 Å²	43.8	36%	0.355	30%	0.295	S	S	.	.	T	Hydrogen-bonded Turn	trans	-82.8	9.6	171.3	0	0	0	0	0	114.1	H196 G407 S408 E409	H196-A411 PolarHBondContact CD2-O 3.01Å; G407-A411 VanDerWaalsContact O-CB 3.3Å; G407-A411 WeakPolarHBondContact O-CB 3.45Å; G407-A411 PolarHBondContact O-N 3.27Å; S408-A411 CarbonylContact O-C 3.56Å; E409-A411 VanDerWaalsContact C-N 3.34Å
412	G	40.8	Very low	58.4	Low	18 Å²	18	44.5 Å²	44.5	19%	0.186	30%	0.295	C	S	.	.	T	Hydrogen-bonded Turn	trans	-149.6	16.9	-169.4	0	0	0	0	0	115.7	S408 E409 I410 A414	S408-G412 WeakPolarHBondContact O-CA 3.46Å; S408-G412 PolarHBondContact O-N 2.94Å; S408-G412 VanDerWaalsContact O-N 3.09Å; E409-G412 CarbonylContact O-C 3Å; E409-G412 PolarHBondContact O-N 2.94Å; E409-G412 VanDerWaalsContact O-N 3.14Å; I410-G412 VanDerWaalsContact C-N 3.25Å; I410-G412 PolarHBondContact O-N 3.02Å; G412-A414 PolarHBondContact O-N 2.93Å
413	G	39.1	Very low	59.7	Low	52 Å²	52	36.2 Å²	36.2	54%	0.536	26%	0.257	S	S	.	.	S	Bend	trans	66.5	-5.9	170.1	0	0	0	0	0	118.7	E409	E409-G413 PolarHBondContact O-N 2.97Å
414	A	39.1	Very low	61.4	Low	79 Å²	79	33 Å²	33	65%	0.653	22%	0.223	S	C	*	.	S	Bend	trans	-95.3	-4.3	-169.3	0	0	0	0	0	115.7	E409 G412	E409-A414 HydrophobicContact CB-CB 4.42Å; E409-A414 HydrophobicContact CG-CB 4.06Å; E409-A414 PolarHBondContact O-N 3.2Å; G412-A414 PolarHBondContact O-N 2.93Å
415	G	50.3	Low	63.4	Low	20 Å²	20	32.9 Å²	32.9	21%	0.206	22%	0.222	C	C	.	.	S	Bend	trans	168	172.2	-171.9	0	0	0	0	0	111.2	E409 I410 G417	E409-G415 CarbonylContact C-O 3.59Å; E409-G415 WeakPolarHBondContact CB-O 3.36Å; E409-G415 WeakPolarHBondContact OE2-CA 3.29Å; I410-G415 PolarHBondContact N-O 2.9Å; G415-G417 PolarHBondContact O-N 3.42Å
416	P	54.5	Low	65.4	Low	36 Å²	36	31.2 Å²	31.2	23%	0.234	21%	0.208	C	C	.	.	S	Bend		-44.6	60.9	-101.1	36.9	-37.9	0	0	0	116.2	V406 I410 W418 V419	V406-P416 HydrophobicContact CG1-CG 3.84Å; I410-P416 HydrophobicContact CD1-CG 3.98Å; I410-P416 HydrophobicContact CG1-CG 3.91Å; P416-W418 PolarHBondContact O-N 3.45Å; P416-V419 HydrophobicContact CB-CG2 4.47Å; P416-V419 WeakPolarHBondContact O-CG2 3.39Å; P416-V419 PolarHBondContact O-N 3.47Å
417	G	66.1	Low	67.4	Low	28 Å²	28	29.3 Å²	29.3	29%	0.289	20%	0.197	S	C	.	.	T	Hydrogen-bonded Turn	trans	-65.9	13.6	174.7	0	0	0	0	0	115.1	G415 P421	G415-G417 PolarHBondContact O-N 3.42Å; G417-P421 WeakPolarHBondContact O-CD 3.38Å; G417-P421 VanDerWaalsContact O-CG 3.31Å; G417-P421 WeakPolarHBondContact O-CG 3.48Å
418	W	79.3	Confident	69.6	Low	108 Å²	108	30 Å²	30	41%	0.409	20%	0.2	S	C	.	.	T	Hydrogen-bonded Turn	trans	-81.9	-23	169	64.2	-98.8	0	0	0	112.8	W222 P416 P421 F422	W222-W418 HydrophobicContact CB-CB 4.48Å; W222-W418 HydrophobicContact CD2-CB 3.38Å; W222-W418 HydrophobicContact CD2-CG 4.4Å; W222-W418 HydrophobicContact CE3-CB 3.88Å; W222-W418 HydrophobicContact CG-CB 3.63Å; W222-W418 HydrophobicContact CH2-CB 4.22Å; W222-W418 HydrophobicContact CH2-CG 4.34Å; W222-W418 HydrophobicContact CZ2-CB 3.76Å; W222-W418 HydrophobicContact CZ2-CG 4.19Å; W222-W418 HydrophobicContact CZ3-CB 4.27Å; W222-W418 HydrophobicContact CZ3-CE3 4.44Å; P416-W418 PolarHBondContact O-N 3.45Å; W418-P421 WeakPolarHBondContact O-CD 3.21Å; W418-P421 WeakPolarHBondContact O-CG 3.16Å; W418-F422 HydrophobicContact CE3-CB 4.11Å; W418-F422 HydrophobicContact CE3-CG 4.42Å; W418-F422 HydrophobicContact CZ3-CB 4.49Å; W418-F422 HydrophobicContact CZ3-CG 4.4Å; W418-F422 WeakPolarHBondContact O-CB 3.33Å; W418-F422 PolarHBondContact O-N 2.94Å
419	V	79.3	Confident	71.7	Confident	11 Å²	11	27.6 Å²	27.6	7%	0.067	18%	0.181	C	C	.	.	H	α-helix	trans	-66.8	-50.3	-173.7	-170.8	0	0	0	0	110.9	F331 T332 P416 F422 T423	F331-V419 HydrophobicContact CD1-CG1 4.27Å; F331-V419 HydrophobicContact CE1-CG1 4.37Å; T332-V419 HydrophobicContact CG2-CB 4.12Å; T332-V419 HydrophobicContact CG2-CG1 3.39Å; P416-V419 HydrophobicContact CB-CG2 4.47Å; P416-V419 WeakPolarHBondContact O-CG2 3.39Å; P416-V419 PolarHBondContact O-N 3.47Å; V419-F422 PolarHBondContact O-N 2.83Å; V419-T423 PolarHBondContact O-N 2.94Å; V419-T423 PolarHBondContact O-OG1 2.9Å
420	L	84.5	Confident	73.8	Confident	13 Å²	13	24.3 Å²	24.3	7%	0.068	17%	0.166	C	C	.	.	H	α-helix	trans	-53.7	-54.5	177.3	-64.7	170.4	0	0	0	113.1	L188 H191 A192 T332 I410 F422 T423 A424	L188-L420 HydrophobicContact CD2-CD2 3.69Å; H191-L420 HydrophobicContact CB-CD1 4.48Å; A192-L420 HydrophobicContact CB-CB 4.27Å; T332-L420 HydrophobicContact CG2-CD2 3.91Å; I410-L420 HydrophobicContact CG2-CD1 3.99Å; I410-L420 HydrophobicContact CG2-CG 4.26Å; L420-F422 VanDerWaalsContact C-N 3.34Å; L420-F422 PolarHBondContact O-N 2.96Å; L420-T423 PolarHBondContact O-N 3.42Å; L420-A424 PolarHBondContact O-N 2.99Å
421	P	90	Very high	75.9	Confident	0 Å²	0	23.5 Å²	23.5	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-66.8	-33.2	177.6	22.6	-30.2	0	0	0	113	A192 V219 W222 V223 G417 W418 A424 G425	A192-P421 HydrophobicContact CB-CB 4.44Å; A192-P421 HydrophobicContact CB-CG 4.14Å; V219-P421 HydrophobicContact CG1-CB 4.03Å; W222-P421 HydrophobicContact CB-CB 3.83Å; W222-P421 HydrophobicContact CB-CG 3.6Å; W222-P421 HydrophobicContact CG-CG 4.39Å; V223-P421 VanDerWaalsContact CA-O 3.24Å; V223-P421 WeakPolarHBondContact CA-O 3.14Å; V223-P421 HydrophobicContact CG2-CB 3.64Å; V223-P421 WeakPolarHBondContact CG2-O 3.34Å; G417-P421 WeakPolarHBondContact O-CD 3.38Å; G417-P421 VanDerWaalsContact O-CG 3.31Å; G417-P421 WeakPolarHBondContact O-CG 3.48Å; W418-P421 WeakPolarHBondContact O-CD 3.21Å; W418-P421 WeakPolarHBondContact O-CG 3.16Å; P421-A424 WeakPolarHBondContact O-CB 3.47Å; P421-A424 PolarHBondContact O-N 2.92Å; P421-G425 PolarHBondContact O-N 3.08Å
422	F	89.9	Confident	78.2	Confident	48 Å²	48	24.3 Å²	24.3	21%	0.211	16%	0.162	C	C	.	.	H	α-helix	trans	-62.9	-45.3	174.1	-179.3	-87.2	0	0	0	111.8	W222 G226 A229 W418 V419 L420 G425 G426	W222-F422 WeakPolarHBondContact O-CA 3.04Å; G226-F422 WeakPolarHBondContact CA-O 3.45Å; A229-F422 HydrophobicContact CB-CE2 3.79Å; A229-F422 HydrophobicContact CB-CZ 3.7Å; W418-F422 HydrophobicContact CE3-CB 4.11Å; W418-F422 HydrophobicContact CE3-CG 4.42Å; W418-F422 HydrophobicContact CZ3-CB 4.49Å; W418-F422 HydrophobicContact CZ3-CG 4.4Å; W418-F422 WeakPolarHBondContact O-CB 3.33Å; W418-F422 PolarHBondContact O-N 2.94Å; V419-F422 PolarHBondContact O-N 2.83Å; L420-F422 VanDerWaalsContact C-N 3.34Å; L420-F422 PolarHBondContact O-N 2.96Å; F422-G425 PolarHBondContact O-N 3.32Å; F422-G426 PolarHBondContact O-N 3.29Å
423	T	87.6	Confident	80.7	Confident	3 Å²	3	26.1 Å²	26.1	2%	0.018	17%	0.17	C	C	.	.	H	α-helix	trans	-61.2	-44.7	173.8	-61.9	0	0	0	0	111	L188 H329 V419 L420 G425 G426 F427	L188-T423 HydrophobicContact CD1-CG2 3.88Å; H329-T423 HydrophobicContact CB-CG2 3.91Å; V419-T423 PolarHBondContact O-N 2.94Å; V419-T423 PolarHBondContact O-OG1 2.9Å; L420-T423 PolarHBondContact O-N 3.42Å; T423-G425 VanDerWaalsContact C-N 3.26Å; T423-G425 PolarHBondContact O-N 3.03Å; T423-G426 CarbonylContact O-C 3.55Å; T423-G426 WeakPolarHBondContact O-CA 3.36Å; T423-G426 PolarHBondContact O-N 2.86Å; T423-F427 HydrophobicContact CG2-CD1 4.37Å; T423-F427 HydrophobicContact CG2-CE1 4.38Å; T423-F427 PolarHBondContact O-N 3.17Å
424	A	92.6	Very high	83	Confident	0 Å²	0	24.7 Å²	24.7	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-56.8	-40	174.6	0	0	0	0	0	112.2	A184 L188 I189 L420 P421 F427 I428	A184-A424 HydrophobicContact CB-CB 4Å; L188-A424 HydrophobicContact CB-CB 3.78Å; L188-A424 HydrophobicContact CD1-CB 3.91Å; I189-A424 HydrophobicContact CD1-CB 4.19Å; I189-A424 HydrophobicContact CG1-CB 3.8Å; L420-A424 PolarHBondContact O-N 2.99Å; P421-A424 WeakPolarHBondContact O-CB 3.47Å; P421-A424 PolarHBondContact O-N 2.92Å; A424-F427 PolarHBondContact O-N 3.35Å; A424-I428 WeakPolarHBondContact O-CB 3.49Å; A424-I428 WeakPolarHBondContact O-CD1 3.37Å; A424-I428 VanDerWaalsContact O-CG1 3.24Å; A424-I428 WeakPolarHBondContact O-CG1 3.49Å; A424-I428 PolarHBondContact O-N 2.91Å
425	G	94	Very high	85.4	Confident	0 Å²	0	21 Å²	21	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-62.2	-39.5	172.6	0	0	0	0	0	113.5	V223 I227 P421 F422 T423 Y429	V223-G425 WeakPolarHBondContact O-CA 3.27Å; I227-G425 VanDerWaalsContact CG1-O 3.22Å; I227-G425 WeakPolarHBondContact CG1-O 3.3Å; P421-G425 PolarHBondContact O-N 3.08Å; F422-G425 PolarHBondContact O-N 3.32Å; T423-G425 VanDerWaalsContact C-N 3.26Å; T423-G425 PolarHBondContact O-N 3.03Å; G425-Y429 WeakPolarHBondContact O-CB 3.43Å; G425-Y429 PolarHBondContact O-N 3.34Å
426	G	90.8	Very high	87.4	Confident	0 Å²	0	22.3 Å²	22.3	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-63.9	-45.6	172.3	0	0	0	0	0	112.8	F422 T423 Y429 V430	F422-G426 PolarHBondContact O-N 3.29Å; T423-G426 CarbonylContact O-C 3.55Å; T423-G426 WeakPolarHBondContact O-CA 3.36Å; T423-G426 PolarHBondContact O-N 2.86Å; G426-Y429 WeakPolarHBondContact O-CB 3.32Å; G426-Y429 PolarHBondContact O-N 3.09Å; G426-Y429 VanDerWaalsContact O-N 3.13Å; G426-V430 WeakPolarHBondContact O-CG2 3.41Å; G426-V430 PolarHBondContact O-N 2.97Å
427	F	93.1	Very high	89.2	Confident	1 Å²	1	23.4 Å²	23.4	0%	0.004	13%	0.13	C	C	.	.	H	α-helix	trans	-62.2	-46	177.4	-87.1	21.8	0	0	0	112.2	L180 D183 A184 L188 A325 H329 H362 T423 A424 Y429 V430 A431	L180-F427 HydrophobicContact CB-CD2 4.5Å; L180-F427 HydrophobicContact CD2-CD1 3.98Å; L180-F427 HydrophobicContact CD2-CD2 3.67Å; L180-F427 HydrophobicContact CD2-CE1 3.91Å; L180-F427 HydrophobicContact CD2-CE2 3.62Å; L180-F427 HydrophobicContact CD2-CG 3.82Å; L180-F427 HydrophobicContact CD2-CZ 3.72Å; D183-F427 HydrophobicContact CB-CD2 4.23Å; D183-F427 HydrophobicContact CB-CE2 4.33Å; D183-F427 WeakPolarHBondContact OD2-CD2 3.48Å; D183-F427 WeakPolarHBondContact OD2-CE2 3.28Å; A184-F427 HydrophobicContact CB-CB 4.08Å; L188-F427 HydrophobicContact CD1-CD2 4.36Å; A325-F427 HydrophobicContact CB-CD1 3.83Å; A325-F427 HydrophobicContact CB-CE1 3.85Å; H329-F427 HydrophobicContact CB-CE1 3.74Å; H329-F427 HydrophobicContact CB-CE2 4.22Å; H329-F427 HydrophobicContact CB-CZ 3.36Å; H329-F427 AromaticContact CE1-CE2 3.71Å; H329-F427 AromaticContact CG-CE2 3.78Å; H329-F427 AromaticContact CG-CZ 3.35Å; H329-F427 AromaticContact ND1-CE2 3.23Å; H329-F427 WeakPolarHBondContact ND1-CE2 3.44Å; H329-F427 AromaticContact ND1-CZ 3.32Å; H329-F427 VanDerWaalsContact ND1-CZ 3.32Å; H329-F427 WeakPolarHBondContact ND1-CZ 3.29Å; H362-F427 AromaticContact CE1-CE2 3.79Å; T423-F427 HydrophobicContact CG2-CD1 4.37Å; T423-F427 HydrophobicContact CG2-CE1 4.38Å; T423-F427 PolarHBondContact O-N 3.17Å; A424-F427 PolarHBondContact O-N 3.35Å; F427-Y429 VanDerWaalsContact C-N 3.27Å; F427-Y429 PolarHBondContact O-N 3.01Å; F427-V430 PolarHBondContact O-N 2.98Å; F427-A431 WeakPolarHBondContact O-CB 3.26Å; F427-A431 PolarHBondContact O-N 3.19Å
428	I	96.1	Very high	90.2	Very high	18 Å²	18	23.4 Å²	23.4	9%	0.092	12%	0.122	C	C	.	.	H	α-helix	trans	-57.2	-42.6	172.2	-69.8	163.4	0	0	0	110.3	L181 A184 F185 I189 V223 I227 A424 T432	L181-I428 HydrophobicContact CD2-CG1 4.38Å; A184-I428 HydrophobicContact CB-CD1 4.15Å; A184-I428 HydrophobicContact CB-CG1 3.76Å; F185-I428 HydrophobicContact CE1-CD1 4.21Å; F185-I428 HydrophobicContact CE2-CD1 3.86Å; F185-I428 HydrophobicContact CE2-CG1 3.86Å; F185-I428 HydrophobicContact CZ-CD1 3.66Å; F185-I428 HydrophobicContact CZ-CG1 4.16Å; I189-I428 HydrophobicContact CD1-CD1 4.22Å; V223-I428 HydrophobicContact CG1-CD1 4.04Å; I227-I428 HydrophobicContact CD1-CG2 4.18Å; A424-I428 WeakPolarHBondContact O-CB 3.49Å; A424-I428 WeakPolarHBondContact O-CD1 3.37Å; A424-I428 VanDerWaalsContact O-CG1 3.24Å; A424-I428 WeakPolarHBondContact O-CG1 3.49Å; A424-I428 PolarHBondContact O-N 2.91Å; I428-T432 HydrophobicContact CG2-CG2 4.31Å; I428-T432 VanDerWaalsContact O-CB 3.32Å; I428-T432 WeakPolarHBondContact O-CB 3.4Å; I428-T432 WeakPolarHBondContact O-CG2 3.41Å; I428-T432 PolarHBondContact O-N 3.47Å; I428-T432 PolarHBondContact O-OG1 3.43Å
429	Y	94.5	Very high	90.6	Very high	14 Å²	14	19.3 Å²	19.3	6%	0.055	11%	0.108	C	C	.	.	H	α-helix	trans	-64.8	-48.9	178.3	-168.5	-86	0	0	0	112.7	I227 F230 L231 E234 L321 G425 G426 F427 T432 V433	I227-Y429 HydrophobicContact CG2-CD2 4.16Å; F230-Y429 HydrophobicContact CB-CD1 3.64Å; F230-Y429 HydrophobicContact CB-CD2 4.23Å; F230-Y429 HydrophobicContact CB-CE1 4.26Å; F230-Y429 HydrophobicContact CB-CG 3.63Å; F230-Y429 HydrophobicContact CD1-CD1 4.42Å; L231-Y429 WeakPolarHBondContact CA-OH 3.41Å; L231-Y429 HydrophobicContact CB-CD2 4.43Å; L231-Y429 HydrophobicContact CB-CE2 3.62Å; L231-Y429 HydrophobicContact CD1-CE2 4.35Å; L231-Y429 HydrophobicContact CG-CE2 4.19Å; E234-Y429 HydrophobicContact CB-CE1 4.38Å; E234-Y429 WeakPolarHBondContact OE2-CE1 3.27Å; E234-Y429 PolarHBondContact OE2-OH 3.42Å; L321-Y429 HydrophobicContact CD1-CE1 4.21Å; G425-Y429 WeakPolarHBondContact O-CB 3.43Å; G425-Y429 PolarHBondContact O-N 3.34Å; G426-Y429 WeakPolarHBondContact O-CB 3.32Å; G426-Y429 PolarHBondContact O-N 3.09Å; G426-Y429 VanDerWaalsContact O-N 3.13Å; F427-Y429 VanDerWaalsContact C-N 3.27Å; F427-Y429 PolarHBondContact O-N 3.01Å; Y429-T432 PolarHBondContact O-N 2.91Å; Y429-V433 HydrophobicContact CD1-CB 4.23Å; Y429-V433 HydrophobicContact CD2-CG2 3.95Å; Y429-V433 HydrophobicContact CE1-CB 3.95Å; Y429-V433 HydrophobicContact CE1-CG1 4.05Å; Y429-V433 HydrophobicContact CE1-CG2 4.38Å; Y429-V433 HydrophobicContact CE2-CB 4.24Å; Y429-V433 HydrophobicContact CE2-CG1 4.37Å; Y429-V433 HydrophobicContact CE2-CG2 3.79Å; Y429-V433 HydrophobicContact CG-CG2 4.31Å; Y429-V433 WeakPolarHBondContact O-CA 3.32Å; Y429-V433 VanDerWaalsContact O-CB 3.29Å; Y429-V433 WeakPolarHBondContact O-CB 3.44Å; Y429-V433 PolarHBondContact O-N 3.14Å
430	V	92.4	Very high	91.2	Very high	1 Å²	1	25.7 Å²	25.7	1%	0.006	14%	0.141	C	C	.	.	I	π-helix	trans	-59.8	-50.7	178.6	171.7	0	0	0	0	110.1	L180 F230 L321 N322 A325 I369 G426 F427 S434 V435	L180-V430 HydrophobicContact CD1-CG1 3.96Å; F230-V430 HydrophobicContact CD1-CG2 4.16Å; F230-V430 HydrophobicContact CE1-CG2 4.12Å; L321-V430 HydrophobicContact CB-CG2 4.31Å; N322-V430 WeakPolarHBondContact OD1-CG1 3.29Å; A325-V430 HydrophobicContact CB-CG2 3.86Å; I369-V430 HydrophobicContact CD1-CG1 4.42Å; G426-V430 WeakPolarHBondContact O-CG2 3.41Å; G426-V430 PolarHBondContact O-N 2.97Å; F427-V430 PolarHBondContact O-N 2.98Å; V430-S434 WeakPolarHBondContact O-CA 3.24Å; V430-S434 VanDerWaalsContact O-CB 3.26Å; V430-S434 WeakPolarHBondContact O-CB 2.99Å; V430-S434 PolarHBondContact O-N 3.21Å; V430-V435 HydrophobicContact CG1-CG2 4.31Å; V430-V435 PolarHBondContact O-N 2.98Å
431	A	93.8	Very high	91.3	Very high	0 Å²	0	32 Å²	32	0%	0	16%	0.164	C	C	.	.	I	π-helix	trans	-59.4	-51.7	178.5	0	0	0	0	0	112.4	L180 L181 F427 V435 L436	L180-A431 HydrophobicContact CB-CB 4.07Å; L180-A431 HydrophobicContact CD1-CB 4.49Å; L181-A431 HydrophobicContact CD1-CB 4.28Å; L181-A431 HydrophobicContact CD2-CB 3.9Å; L181-A431 HydrophobicContact CG-CB 3.69Å; F427-A431 WeakPolarHBondContact O-CB 3.26Å; F427-A431 PolarHBondContact O-N 3.19Å; A431-V435 WeakPolarHBondContact O-CB 3.38Å; A431-L436 WeakPolarHBondContact O-CB 3.4Å; A431-L436 WeakPolarHBondContact O-CD1 3.1Å; A431-L436 PolarHBondContact O-N 2.97Å
432	T	94.6	Very high	90.8	Very high	61 Å²	61	41.8 Å²	41.8	37%	0.374	21%	0.21	S	C	.	.	I	π-helix	trans	-80.9	-28.7	-171.9	60.9	0	0	0	0	115.1	L181 I428 Y429 L436 P437	L181-T432 HydrophobicContact CD2-CG2 4.15Å; I428-T432 HydrophobicContact CG2-CG2 4.31Å; I428-T432 VanDerWaalsContact O-CB 3.32Å; I428-T432 WeakPolarHBondContact O-CB 3.4Å; I428-T432 WeakPolarHBondContact O-CG2 3.41Å; I428-T432 PolarHBondContact O-N 3.47Å; I428-T432 PolarHBondContact O-OG1 3.43Å; Y429-T432 PolarHBondContact O-N 2.91Å; T432-L436 HydrophobicContact CG2-CD1 4.15Å; T432-P437 WeakPolarHBondContact O-CD 3.35Å
433	V	92.4	Very high	90.5	Very high	56 Å²	56	41.6 Å²	41.6	34%	0.339	22%	0.217	S	C	.	.	I	π-helix	trans	-109.3	-34.6	-173.5	-173.5	0	0	0	0	112.7	Y429	Y429-V433 HydrophobicContact CD1-CB 4.23Å; Y429-V433 HydrophobicContact CD2-CG2 3.95Å; Y429-V433 HydrophobicContact CE1-CB 3.95Å; Y429-V433 HydrophobicContact CE1-CG1 4.05Å; Y429-V433 HydrophobicContact CE1-CG2 4.38Å; Y429-V433 HydrophobicContact CE2-CB 4.24Å; Y429-V433 HydrophobicContact CE2-CG1 4.37Å; Y429-V433 HydrophobicContact CE2-CG2 3.79Å; Y429-V433 HydrophobicContact CG-CG2 4.31Å; Y429-V433 WeakPolarHBondContact O-CA 3.32Å; Y429-V433 VanDerWaalsContact O-CB 3.29Å; Y429-V433 WeakPolarHBondContact O-CB 3.44Å; Y429-V433 PolarHBondContact O-N 3.14Å
434	S	87.8	Confident	90.6	Very high	22 Å²	22	44.7 Å²	44.7	15%	0.154	24%	0.239	C	C	.	.	I	π-helix	trans	-93.3	-32.3	179.2	-61.7	0	0	0	0	113.3	V430	V430-S434 WeakPolarHBondContact O-CA 3.24Å; V430-S434 VanDerWaalsContact O-CB 3.26Å; V430-S434 WeakPolarHBondContact O-CB 2.99Å; V430-S434 PolarHBondContact O-N 3.21Å
435	V	90.6	Very high	90.6	Very high	1 Å²	1	50.2 Å²	50.2	1%	0.006	28%	0.275	C	S	.	.	I	π-helix	trans	-103.4	-62.3	-170.6	174.2	0	0	0	0	113.3	L173 I369 V430 A431 P437 E438 L439	L173-V435 HydrophobicContact CD1-CB 4.17Å; L173-V435 HydrophobicContact CD1-CG1 3.47Å; L173-V435 VanDerWaalsContact CD1-CG1 3.47Å; L173-V435 HydrophobicContact CD1-CG2 3.88Å; L173-V435 HydrophobicContact CD2-CG1 4.47Å; L173-V435 HydrophobicContact CG-CG1 3.64Å; L173-V435 WeakPolarHBondContact O-CG1 3.14Å; I369-V435 HydrophobicContact CD1-CG2 3.55Å; I369-V435 HydrophobicContact CG1-CG2 3.85Å; V430-V435 HydrophobicContact CG1-CG2 4.31Å; V430-V435 PolarHBondContact O-N 2.98Å; A431-V435 WeakPolarHBondContact O-CB 3.38Å; V435-P437 VanDerWaalsContact C-CD 3.42Å; V435-P437 VanDerWaalsContact C-N 3.3Å; V435-P437 VanDerWaalsContact O-N 3.15Å; V435-E438 VanDerWaalsContact O-CB 3.29Å; V435-E438 WeakPolarHBondContact O-CB 3.35Å; V435-E438 PolarHBondContact O-N 2.85Å; V435-L439 HydrophobicContact CG1-CD1 4.24Å
436	L	92.5	Very high	90.5	Very high	48 Å²	48	55.6 Å²	55.6	25%	0.251	30%	0.303	S	S	.	.	H	α-helix	trans	-50.1	-39.5	-177	-93.3	144.6	0	0	0	114.3	S177 L181 A431 T432 E438 L439 L440 L455	S177-L436 WeakPolarHBondContact OG-CD1 3.31Å; L181-L436 HydrophobicContact CD1-CD1 4.07Å; A431-L436 WeakPolarHBondContact O-CB 3.4Å; A431-L436 WeakPolarHBondContact O-CD1 3.1Å; A431-L436 PolarHBondContact O-N 2.97Å; T432-L436 HydrophobicContact CG2-CD1 4.15Å; L436-E438 PolarHBondContact O-N 3.22Å; L436-L439 PolarHBondContact O-N 2.97Å; L436-L440 WeakPolarHBondContact O-CG 3.3Å; L436-L440 PolarHBondContact O-N 3.36Å; L436-L455 HydrophobicContact CD2-CD1 4.28Å
437	P	91	Very high	90.5	Very high	58 Å²	58	56.8 Å²	56.8	38%	0.377	31%	0.308	S	S	.	.	H	α-helix	trans	-68.1	-15.7	177	-23.6	37	0	0	0	115.5	T432 V435	T432-P437 WeakPolarHBondContact O-CD 3.35Å; V435-P437 VanDerWaalsContact C-CD 3.42Å; V435-P437 VanDerWaalsContact C-N 3.3Å; V435-P437 VanDerWaalsContact O-N 3.15Å
438	E	87.3	Confident	90.5	Very high	29 Å²	29	58.9 Å²	58.9	14%	0.136	32%	0.323	C	S	.	.	H	α-helix	trans	-76.8	-42	170.3	-174.9	73.9	-116.5	0	0	110.6	L173 Q372 V435 L436 L440 R441	L173-E438 HydrophobicContact CD2-CB 3.93Å; L173-E438 HydrophobicContact CD2-CG 3.65Å; Q372-E438 HydrophobicContact CG-CG 4.37Å; Q372-E438 PolarHBondContact NE2-OE1 3.01Å; Q372-E438 PolarHBondContact NE2-OE2 3.12Å; V435-E438 VanDerWaalsContact O-CB 3.29Å; V435-E438 WeakPolarHBondContact O-CB 3.35Å; V435-E438 PolarHBondContact O-N 2.85Å; L436-E438 PolarHBondContact O-N 3.22Å; E438-L440 PolarHBondContact O-N 3.07Å; E438-R441 WeakPolarHBondContact O-CB 3.08Å; E438-R441 WeakPolarHBondContact O-CG 3.29Å; E438-R441 PolarHBondContact O-N 3.46Å; E438-R441 IonicContact OE1-CZ 3.78Å; E438-R441 IonicContact OE1-NH1 2.7Å; E438-R441 PolarHBondContact OE1-NH1 2.86Å; E438-R441 IonicContact OE2-NH1 2.82Å; E438-R441 PolarHBondContact OE2-NH1 3.02Å
439	L	88.7	Confident	90.3	Very high	21 Å²	21	62.7 Å²	62.7	11%	0.11	34%	0.343	C	S	.	.	H	α-helix	trans	-67.4	-21.7	177.9	-55.3	172.3	0	0	0	113.1	Q170 L173 V435 L436 R441	Q170-L439 HydrophobicContact CB-CD2 4.48Å; Q170-L439 WeakPolarHBondContact O-CD2 3.3Å; L173-L439 HydrophobicContact CB-CD2 4.28Å; L173-L439 HydrophobicContact CD2-CD2 4.16Å; L173-L439 HydrophobicContact CG-CD2 4.12Å; V435-L439 HydrophobicContact CG1-CD1 4.24Å; L436-L439 PolarHBondContact O-N 2.97Å; L439-R441 PolarHBondContact O-N 3.49Å
440	L	90	Very high	90.3	Very high	145 Å²	145	63.5 Å²	63.5	76%	0.759	35%	0.348	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.8	5.9	176.1	-67.3	175.2	0	0	0	113.9	L436 E438	L436-L440 WeakPolarHBondContact O-CG 3.3Å; L436-L440 PolarHBondContact O-N 3.36Å; E438-L440 PolarHBondContact O-N 3.07Å
441	R	86.7	Confident	90.4	Very high	145 Å²	145	64 Å²	64	55%	0.547	35%	0.351	S	S	.	.	S	Bend	trans	-78.6	165.6	175.4	-68.3	-169.7	169.4	109.4	16.2	111.8	E438 L439 A443	E438-R441 WeakPolarHBondContact O-CB 3.08Å; E438-R441 WeakPolarHBondContact O-CG 3.29Å; E438-R441 PolarHBondContact O-N 3.46Å; E438-R441 IonicContact OE1-CZ 3.78Å; E438-R441 IonicContact OE1-NH1 2.7Å; E438-R441 PolarHBondContact OE1-NH1 2.86Å; E438-R441 IonicContact OE2-NH1 2.82Å; E438-R441 PolarHBondContact OE2-NH1 3.02Å; L439-R441 PolarHBondContact O-N 3.49Å; R441-A443 PolarHBondContact O-N 3.38Å; R441-A443 VanDerWaalsContact O-N 3.09Å
442	E	80.3	Confident	90.4	Very high	206 Å²	206	67.9 Å²	67.9	96%	0.963	37%	0.374	S	S	*	.	S	Bend	trans	-57.3	113.9	-178.1	-67.3	175.8	-168.1	0	0	111.7
443	A	83.8	Confident	90.4	Very high	44 Å²	44	68.9 Å²	68.9	36%	0.364	38%	0.377	S	S	.	.			trans	-131.8	162	175.6	0	0	0	0	0	110	R441 Q447	R441-A443 PolarHBondContact O-N 3.38Å; R441-A443 VanDerWaalsContact O-N 3.09Å; A443-Q447 HydrophobicContact CB-CB 4.13Å; A443-Q447 HydrophobicContact CB-CG 3.87Å
444	S	90.5	Very high	90.4	Very high	68 Å²	68	66.3 Å²	66.3	48%	0.476	36%	0.361	S	S	.	.			trans	-69.6	152.4	171.9	71.6	0	0	0	0	110.1	L446 Q447 S448	S444-L446 PolarHBondContact O-N 3.45Å; S444-L446 VanDerWaalsContact O-N 3.14Å; S444-Q447 WeakPolarHBondContact O-CA 3.28Å; S444-Q447 WeakPolarHBondContact O-CB 3.48Å; S444-Q447 PolarHBondContact O-N 3.31Å; S444-Q447 VanDerWaalsContact OG-CB 3.31Å; S444-Q447 WeakPolarHBondContact OG-CB 3.24Å; S444-Q447 PolarHBondContact OG-N 2.97Å; S444-S448 PolarHBondContact O-N 2.87Å; S444-S448 PolarHBondContact O-OG 3.41Å
445	P	91.1	Very high	90.7	Very high	116 Å²	116	67.2 Å²	67.2	75%	0.753	36%	0.364	S	S	*	.	H	α-helix	trans	-59.7	-30.2	-176.9	22.1	-33.8	0	0	0	113.5	L449	P445-L449 WeakPolarHBondContact O-CB 3.49Å; P445-L449 PolarHBondContact O-N 3.04Å; P445-L449 VanDerWaalsContact O-N 3.09Å
446	L	91.4	Very high	90.9	Very high	114 Å²	114	71.2 Å²	71.2	60%	0.597	39%	0.385	S	S	*	.	H	α-helix	trans	-71.2	-40.1	172.6	-66.6	178.4	0	0	0	112.2	S444 L449 L450	S444-L446 PolarHBondContact O-N 3.45Å; S444-L446 VanDerWaalsContact O-N 3.14Å; L446-L449 PolarHBondContact O-N 2.85Å; L446-L450 WeakPolarHBondContact O-CG 3.49Å; L446-L450 PolarHBondContact O-N 2.59Å
447	Q	91.4	Very high	91	Very high	24 Å²	24	70.1 Å²	70.1	11%	0.112	39%	0.385	C	S	.	.	H	α-helix	trans	-63.9	-46	175.6	177.7	64.9	31.2	0	0	110.9	S167 A443 S444 L449 L450 E451	S167-Q447 PolarHBondContact O-NE2 3.19Å; S167-Q447 PolarHBondContact OG-OE1 3.33Å; A443-Q447 HydrophobicContact CB-CB 4.13Å; A443-Q447 HydrophobicContact CB-CG 3.87Å; S444-Q447 WeakPolarHBondContact O-CA 3.28Å; S444-Q447 WeakPolarHBondContact O-CB 3.48Å; S444-Q447 PolarHBondContact O-N 3.31Å; S444-Q447 VanDerWaalsContact OG-CB 3.31Å; S444-Q447 WeakPolarHBondContact OG-CB 3.24Å; S444-Q447 PolarHBondContact OG-N 2.97Å; Q447-L449 VanDerWaalsContact C-N 3.31Å; Q447-L449 PolarHBondContact O-N 3.41Å; Q447-L450 PolarHBondContact O-N 3.38Å; Q447-L450 VanDerWaalsContact O-N 3.14Å; Q447-E451 VanDerWaalsContact CG-OE1 3.26Å; Q447-E451 WeakPolarHBondContact CG-OE1 3.47Å; Q447-E451 PolarHBondContact NE2-OE1 3.44Å; Q447-E451 WeakPolarHBondContact O-CG 3.36Å; Q447-E451 PolarHBondContact O-N 3.45Å
448	S	92.5	Very high	91	Very high	46 Å²	46	67.3 Å²	67.3	32%	0.322	37%	0.367	S	S	.	.	H	α-helix	trans	-62.1	-36.3	175.1	-58	0	0	0	0	112.7	S444 E451 V452	S444-S448 PolarHBondContact O-N 2.87Å; S444-S448 PolarHBondContact O-OG 3.41Å; S448-E451 PolarHBondContact O-N 3.32Å; S448-V452 WeakPolarHBondContact O-CG2 3.46Å; S448-V452 PolarHBondContact O-N 2.97Å
449	L	93.6	Very high	91.4	Very high	98 Å²	98	68.1 Å²	68.1	51%	0.513	37%	0.374	S	S	.	.	H	α-helix	trans	-64.7	-43.7	173	178.4	62	0	0	0	111.5	P445 L446 Q447 E451 V452 L453	P445-L449 WeakPolarHBondContact O-CB 3.49Å; P445-L449 PolarHBondContact O-N 3.04Å; P445-L449 VanDerWaalsContact O-N 3.09Å; L446-L449 PolarHBondContact O-N 2.85Å; Q447-L449 VanDerWaalsContact C-N 3.31Å; Q447-L449 PolarHBondContact O-N 3.41Å; L449-E451 VanDerWaalsContact C-N 3.32Å; L449-E451 PolarHBondContact O-N 2.93Å; L449-V452 PolarHBondContact O-N 3.12Å; L449-L453 HydrophobicContact CD1-CD1 4.38Å; L449-L453 HydrophobicContact CD1-CG 4.38Å; L449-L453 HydrophobicContact CG-CD1 4.15Å; L449-L453 WeakPolarHBondContact O-CB 3.23Å; L449-L453 VanDerWaalsContact O-CG 3.26Å; L449-L453 WeakPolarHBondContact O-CG 3.18Å; L449-L453 PolarHBondContact O-N 2.98Å
450	L	93.4	Very high	91.6	Very high	30 Å²	30	72 Å²	72	16%	0.157	39%	0.394	C	S	.	.	H	α-helix	trans	-64.4	-35.3	175.9	-71.6	169.3	0	0	0	112.3	L24 I171 L446 Q447 L453 G454	L24-L450 HydrophobicContact CD2-CD2 4.43Å; I171-L450 HydrophobicContact CD1-CB 4.06Å; I171-L450 HydrophobicContact CD1-CD1 4.35Å; I171-L450 HydrophobicContact CG1-CB 4.16Å; L446-L450 WeakPolarHBondContact O-CG 3.49Å; L446-L450 PolarHBondContact O-N 2.59Å; Q447-L450 PolarHBondContact O-N 3.38Å; Q447-L450 VanDerWaalsContact O-N 3.14Å; L450-L453 PolarHBondContact O-N 2.98Å; L450-G454 PolarHBondContact O-N 3.28Å
451	E	93.8	Very high	91.5	Very high	13 Å²	13	66.5 Å²	66.5	6%	0.061	37%	0.365	C	S	.	.	H	α-helix	trans	-67.4	-45.3	174.3	-73.9	160	-173.6	0	0	111.5	Q170 I171 S174 Q447 S448 L449 L453 G454 L455	Q170-E451 HydrophobicContact CB-CG 4.18Å; Q170-E451 WeakPolarHBondContact CB-OE1 3.32Å; I171-E451 HydrophobicContact CG1-CG 4.46Å; S174-E451 WeakPolarHBondContact CB-O 3.41Å; S174-E451 WeakPolarHBondContact OG-CA 3.47Å; S174-E451 PolarHBondContact OG-O 3.13Å; Q447-E451 VanDerWaalsContact CG-OE1 3.26Å; Q447-E451 WeakPolarHBondContact CG-OE1 3.47Å; Q447-E451 PolarHBondContact NE2-OE1 3.44Å; Q447-E451 WeakPolarHBondContact O-CG 3.36Å; Q447-E451 PolarHBondContact O-N 3.45Å; S448-E451 PolarHBondContact O-N 3.32Å; L449-E451 VanDerWaalsContact C-N 3.32Å; L449-E451 PolarHBondContact O-N 2.93Å; E451-L453 VanDerWaalsContact C-N 3.33Å; E451-L453 PolarHBondContact O-N 3.27Å; E451-G454 PolarHBondContact O-N 2.86Å; E451-L455 PolarHBondContact O-N 2.9Å
452	V	94.3	Very high	91.7	Very high	81 Å²	81	59.7 Å²	59.7	49%	0.491	34%	0.339	S	S	.	.	H	α-helix	trans	-61.4	-41.3	173.4	171.1	0	0	0	0	111.2	S448 L449 L455 L456	S448-V452 WeakPolarHBondContact O-CG2 3.46Å; S448-V452 PolarHBondContact O-N 2.97Å; L449-V452 PolarHBondContact O-N 3.12Å; V452-L455 PolarHBondContact O-N 3.01Å; V452-L456 HydrophobicContact CG1-CD1 4.11Å; V452-L456 HydrophobicContact CG1-CG 4.5Å; V452-L456 WeakPolarHBondContact O-CB 3.16Å; V452-L456 VanDerWaalsContact O-CG 3.32Å; V452-L456 WeakPolarHBondContact O-CG 3.27Å; V452-L456 PolarHBondContact O-N 2.8Å
453	L	94.8	Very high	92.2	Very high	82 Å²	82	52.5 Å²	52.5	43%	0.429	31%	0.309	S	S	.	.	H	α-helix	trans	-66.1	-35.1	174.5	-71.6	173	0	0	0	112.5	L449 L450 E451 G457	L449-L453 HydrophobicContact CD1-CD1 4.38Å; L449-L453 HydrophobicContact CD1-CG 4.38Å; L449-L453 HydrophobicContact CG-CD1 4.15Å; L449-L453 WeakPolarHBondContact O-CB 3.23Å; L449-L453 VanDerWaalsContact O-CG 3.26Å; L449-L453 WeakPolarHBondContact O-CG 3.18Å; L449-L453 PolarHBondContact O-N 2.98Å; L450-L453 PolarHBondContact O-N 2.98Å; E451-L453 VanDerWaalsContact C-N 3.33Å; E451-L453 PolarHBondContact O-N 3.27Å; L453-G457 PolarHBondContact O-N 3.29Å
454	G	93.1	Very high	92.4	Very high	1 Å²	1	54.5 Å²	54.5	1%	0.01	31%	0.313	C	S	.	.	H	α-helix	trans	-63.9	-47.2	173	0	0	0	0	0	111.8	S174 F175 L450 E451 G457 G458	S174-G454 WeakPolarHBondContact OG-CA 3.45Å; F175-G454 VanDerWaalsContact CA-O 3.31Å; F175-G454 WeakPolarHBondContact CA-O 3.45Å; L450-G454 PolarHBondContact O-N 3.28Å; E451-G454 PolarHBondContact O-N 2.86Å; G454-G457 CarbonylContact O-C 3.54Å; G454-G457 WeakPolarHBondContact O-CA 3.32Å; G454-G457 PolarHBondContact O-N 3.35Å; G454-G457 VanDerWaalsContact O-N 3.08Å; G454-G458 PolarHBondContact O-N 3.25Å
455	L	94.3	Very high	92.1	Very high	41 Å²	41	51.7 Å²	51.7	22%	0.215	29%	0.293	C	S	.	.	H	α-helix	trans	-61.4	-47.4	176	-173.8	156.6	0	0	0	111.6	S174 G178 L436 E451 V452 G457 G458 V459	S174-L455 WeakPolarHBondContact O-CA 3.28Å; S174-L455 WeakPolarHBondContact O-CB 3.43Å; S174-L455 PolarHBondContact OG-N 2.99Å; G178-L455 WeakPolarHBondContact CA-O 3.41Å; L436-L455 HydrophobicContact CD2-CD1 4.28Å; E451-L455 PolarHBondContact O-N 2.9Å; V452-L455 PolarHBondContact O-N 3.01Å; L455-G457 PolarHBondContact O-N 2.75Å; L455-G458 PolarHBondContact O-N 3Å; L455-V459 HydrophobicContact CD2-CG2 4.28Å; L455-V459 WeakPolarHBondContact O-CG2 3.35Å; L455-V459 PolarHBondContact O-N 3.45Å
456	L	95.3	Very high	91.7	Very high	85 Å²	85	47.8 Å²	47.8	45%	0.445	27%	0.27	S	S	.	.	H	α-helix	trans	-61.3	-35.6	173	-70	174.3	0	0	0	111.7	V452 V459 I460	V452-L456 HydrophobicContact CG1-CD1 4.11Å; V452-L456 HydrophobicContact CG1-CG 4.5Å; V452-L456 WeakPolarHBondContact O-CB 3.16Å; V452-L456 VanDerWaalsContact O-CG 3.32Å; V452-L456 WeakPolarHBondContact O-CG 3.27Å; V452-L456 PolarHBondContact O-N 2.8Å; L456-V459 PolarHBondContact O-N 2.77Å; L456-I460 VanDerWaalsContact O-CB 3.28Å; L456-I460 WeakPolarHBondContact O-CB 3.49Å; L456-I460 WeakPolarHBondContact O-CD1 3.45Å; L456-I460 WeakPolarHBondContact O-CG1 3.2Å; L456-I460 PolarHBondContact O-N 2.81Å
457	G	93	Very high	91.4	Very high	25 Å²	25	49.4 Å²	49.4	26%	0.258	28%	0.275	S	S	.	.	H	α-helix	trans	-60	-43.8	173.4	0	0	0	0	0	112.9	L453 G454 L455 M461	L453-G457 PolarHBondContact O-N 3.29Å; G454-G457 CarbonylContact O-C 3.54Å; G454-G457 WeakPolarHBondContact O-CA 3.32Å; G454-G457 PolarHBondContact O-N 3.35Å; G454-G457 VanDerWaalsContact O-N 3.08Å; L455-G457 PolarHBondContact O-N 2.75Å; G457-M461 VanDerWaalsContact O-CB 3.23Å; G457-M461 WeakPolarHBondContact O-CB 3.49Å; G457-M461 PolarHBondContact O-N 2.89Å
458	G	92.6	Very high	90.6	Very high	0 Å²	0	52.2 Å²	52.2	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-63.1	-45.7	174.5	0	0	0	0	0	112.4	G454 L455 M461 M462	G454-G458 PolarHBondContact O-N 3.25Å; L455-G458 PolarHBondContact O-N 3Å; G458-M461 PolarHBondContact O-N 3.13Å; G458-M462 PolarHBondContact O-N 3.39Å
459	V	93.8	Very high	89.4	Confident	45 Å²	45	55.6 Å²	55.6	27%	0.273	30%	0.3	S	S	.	.	H	α-helix	trans	-63.6	-47.8	176.4	177.4	0	0	0	0	111.4	G178 L455 L456 M461 M462 V463	G178-V459 WeakPolarHBondContact O-CG2 3.34Å; G178-V459 PolarHBondContact O-N 2.78Å; L455-V459 HydrophobicContact CD2-CG2 4.28Å; L455-V459 WeakPolarHBondContact O-CG2 3.35Å; L455-V459 PolarHBondContact O-N 3.45Å; L456-V459 PolarHBondContact O-N 2.77Å; V459-M461 PolarHBondContact O-N 3.41Å; V459-M462 PolarHBondContact O-N 3.36Å; V459-V463 HydrophobicContact CG1-CG2 4.48Å; V459-V463 WeakPolarHBondContact O-CG2 3.46Å; V459-V463 PolarHBondContact O-N 2.96Å
460	I	92.9	Very high	89.2	Confident	103 Å²	103	53.5 Å²	53.5	53%	0.528	29%	0.29	S	S	.	.	H	α-helix	trans	-59.7	-39.1	178.2	-72.8	164.4	0	0	0	110.6	L456 V463 L464	L456-I460 VanDerWaalsContact O-CB 3.28Å; L456-I460 WeakPolarHBondContact O-CB 3.49Å; L456-I460 WeakPolarHBondContact O-CD1 3.45Å; L456-I460 WeakPolarHBondContact O-CG1 3.2Å; L456-I460 PolarHBondContact O-N 2.81Å; I460-V463 WeakPolarHBondContact O-CB 3.48Å; I460-V463 PolarHBondContact O-N 2.81Å; I460-L464 HydrophobicContact CG2-CD1 4.22Å; I460-L464 HydrophobicContact CG2-CG 4.47Å; I460-L464 VanDerWaalsContact O-CG 3.31Å; I460-L464 WeakPolarHBondContact O-CG 3.47Å; I460-L464 PolarHBondContact O-N 3.39Å
461	M	89.8	Confident	89	Confident	29 Å²	29	54.7 Å²	54.7	14%	0.143	30%	0.297	C	S	.	.	H	α-helix	trans	-65.4	-43.7	176.8	-177.6	-140.7	74.3	0	0	111.7	F175 P361 G457 G458 V459 V463 L464 I465	F175-M461 HydrophobicContact CE2-SD 4.36Å; F175-M461 HydrophobicContact CZ-SD 3.64Å; P361-M461 HydrophobicContact CB-CE 3.53Å; P361-M461 HydrophobicContact CB-SD 3.27Å; P361-M461 WeakPolarHBondContact CB-SD 3.39Å; P361-M461 HydrophobicContact CG-CE 3.73Å; P361-M461 HydrophobicContact CG-SD 3.13Å; P361-M461 WeakPolarHBondContact CG-SD 3.37Å; G457-M461 VanDerWaalsContact O-CB 3.23Å; G457-M461 WeakPolarHBondContact O-CB 3.49Å; G457-M461 PolarHBondContact O-N 2.89Å; G458-M461 PolarHBondContact O-N 3.13Å; V459-M461 PolarHBondContact O-N 3.41Å; M461-V463 VanDerWaalsContact C-N 3.33Å; M461-V463 PolarHBondContact O-N 3.47Å; M461-L464 WeakPolarHBondContact O-CB 3.34Å; M461-L464 PolarHBondContact O-N 3.28Å; M461-L464 VanDerWaalsContact O-N 3.11Å; M461-I465 HydrophobicContact CE-CD1 3.84Å; M461-I465 HydrophobicContact CG-CD1 4.34Å; M461-I465 WeakPolarHBondContact O-CG1 3.26Å; M461-I465 PolarHBondContact O-N 2.87Å; M461-I465 HydrophobicContact SD-CD1 4.45Å
462	M	89.9	Confident	88.7	Confident	3 Å²	3	57 Å²	57	2%	0.015	31%	0.31	C	S	.	.	H	α-helix	trans	-63.6	-37.4	172.8	-67.7	-50.9	-54.7	0	0	112.4	G179 D183 L186 H358 G458 V459 L464 I465 A466	G179-M462 WeakPolarHBondContact O-CG 3.04Å; D183-M462 HydrophobicContact CB-CE 3.81Å; D183-M462 HydrophobicContact CB-SD 4.42Å; L186-M462 HydrophobicContact CD1-CB 4.41Å; H358-M462 HydrophobicContact CB-CE 4Å; H358-M462 HydrophobicContact CB-SD 4.2Å; G458-M462 PolarHBondContact O-N 3.39Å; V459-M462 PolarHBondContact O-N 3.36Å; M462-L464 VanDerWaalsContact C-N 3.31Å; M462-L464 PolarHBondContact O-N 3Å; M462-I465 PolarHBondContact O-N 3Å; M462-I465 HydrophobicContact SD-CD1 4.24Å; M462-A466 WeakPolarHBondContact O-CB 3.29Å; M462-A466 PolarHBondContact O-N 3.02Å
463	V	91.2	Very high	88.4	Confident	55 Å²	55	55.6 Å²	55.6	33%	0.333	30%	0.299	S	S	.	.	H	α-helix	trans	-58.1	-43.8	170.7	172.8	0	0	0	0	110.9	L186 V459 I460 M461 A466 H467	L186-V463 HydrophobicContact CD1-CB 4.43Å; L186-V463 HydrophobicContact CD1-CG2 3.44Å; L186-V463 VanDerWaalsContact CD1-CG2 3.44Å; V459-V463 HydrophobicContact CG1-CG2 4.48Å; V459-V463 WeakPolarHBondContact O-CG2 3.46Å; V459-V463 PolarHBondContact O-N 2.96Å; I460-V463 WeakPolarHBondContact O-CB 3.48Å; I460-V463 PolarHBondContact O-N 2.81Å; M461-V463 VanDerWaalsContact C-N 3.33Å; M461-V463 PolarHBondContact O-N 3.47Å; V463-A466 PolarHBondContact O-N 2.89Å; V463-H467 PolarHBondContact O-N 3.45Å; V463-H467 PolarHBondContact O-ND1 3.36Å
464	L	88.8	Confident	88	Confident	86 Å²	86	53.9 Å²	53.9	45%	0.45	29%	0.291	S	S	.	.	H	α-helix	trans	-65.5	-38.1	178.7	-71.5	170.9	0	0	0	112.2	I460 M461 M462 H467 L468	I460-L464 HydrophobicContact CG2-CD1 4.22Å; I460-L464 HydrophobicContact CG2-CG 4.47Å; I460-L464 VanDerWaalsContact O-CG 3.31Å; I460-L464 WeakPolarHBondContact O-CG 3.47Å; I460-L464 PolarHBondContact O-N 3.39Å; M461-L464 WeakPolarHBondContact O-CB 3.34Å; M461-L464 PolarHBondContact O-N 3.28Å; M461-L464 VanDerWaalsContact O-N 3.11Å; M462-L464 VanDerWaalsContact C-N 3.31Å; M462-L464 PolarHBondContact O-N 3Å; L464-H467 PolarHBondContact O-N 3.27Å; L464-L468 WeakPolarHBondContact O-CG 3.48Å; L464-L468 PolarHBondContact O-N 3.11Å
465	I	83.8	Confident	87.6	Confident	9 Å²	9	57.5 Å²	57.5	5%	0.046	31%	0.31	C	S	.	.	H	α-helix	trans	-68.6	-43.7	177.1	-64.5	172.2	0	0	0	110.8	L357 H358 M461 M462 H467 L468 E469	L357-I465 HydrophobicContact CB-CD1 4.39Å; L357-I465 HydrophobicContact CB-CG1 4.5Å; L357-I465 WeakPolarHBondContact O-CD1 3.19Å; H358-I465 HydrophobicContact CB-CD1 3.76Å; H358-I465 HydrophobicContact CB-CG2 4.36Å; M461-I465 HydrophobicContact CE-CD1 3.84Å; M461-I465 HydrophobicContact CG-CD1 4.34Å; M461-I465 WeakPolarHBondContact O-CG1 3.26Å; M461-I465 PolarHBondContact O-N 2.87Å; M461-I465 HydrophobicContact SD-CD1 4.45Å; M462-I465 PolarHBondContact O-N 3Å; M462-I465 HydrophobicContact SD-CD1 4.24Å; I465-H467 PolarHBondContact O-N 3.29Å; I465-L468 WeakPolarHBondContact O-CA 3.49Å; I465-L468 WeakPolarHBondContact O-CB 3.41Å; I465-L468 PolarHBondContact O-N 3.03Å; I465-E469 PolarHBondContact O-N 2.9Å
466	A	83.1	Confident	87.2	Confident	34 Å²	34	58.6 Å²	58.6	28%	0.281	32%	0.317	S	S	.	.	T	Hydrogen-bonded Turn	trans	-65.1	-5.2	173.9	0	0	0	0	0	114.5	M462 V463	M462-A466 WeakPolarHBondContact O-CB 3.29Å; M462-A466 PolarHBondContact O-N 3.02Å; V463-A466 PolarHBondContact O-N 2.89Å
467	H	83.8	Confident	86.5	Confident	148 Å²	148	56.6 Å²	56.6	69%	0.685	31%	0.307	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101	-7.3	168.5	-76.6	70.6	0	0	0	113.5	V463 L464 I465	V463-H467 PolarHBondContact O-N 3.45Å; V463-H467 PolarHBondContact O-ND1 3.36Å; L464-H467 PolarHBondContact O-N 3.27Å; I465-H467 PolarHBondContact O-N 3.29Å
468	L	74.4	Confident	86	Confident	83 Å²	83	59.3 Å²	59.3	44%	0.435	31%	0.311	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95.6	-21.1	174.3	-65.4	173.3	0	0	0	112.3	L357 L464 I465	L357-L468 HydrophobicContact CD1-CD1 4.02Å; L464-L468 WeakPolarHBondContact O-CG 3.48Å; L464-L468 PolarHBondContact O-N 3.11Å; I465-L468 WeakPolarHBondContact O-CA 3.49Å; I465-L468 WeakPolarHBondContact O-CB 3.41Å; I465-L468 PolarHBondContact O-N 3.03Å
469	E	68	Low	85.4	Confident	116 Å²	116	64.6 Å²	64.6	54%	0.542	34%	0.339	S	S	.	.			trans	-70.8	0	169.2	-71.8	165.3	-179.5	0	0	112.5	H187 T354 H358 I465	H187-E469 VanDerWaalsContact CE1-CD 3.44Å; H187-E469 IonicContact CE1-OE1 3.71Å; H187-E469 PolarHBondContact CE1-OE1 3.4Å; H187-E469 IonicContact CE1-OE2 3.79Å; H187-E469 PolarHBondContact CE1-OE2 2.92Å; H187-E469 VanDerWaalsContact CE1-OE2 3.32Å; H187-E469 IonicContact CG-OE2 3.61Å; H187-E469 VanDerWaalsContact ND1-CD 3.31Å; H187-E469 IonicContact ND1-OE1 3.76Å; H187-E469 PolarHBondContact ND1-OE1 3.38Å; H187-E469 IonicContact ND1-OE2 3.21Å; H187-E469 PolarHBondContact ND1-OE2 3.47Å; T354-E469 HydrophobicContact CG2-CG 3.4Å; T354-E469 WeakPolarHBondContact CG2-OE1 3.07Å; H358-E469 IonicContact ND1-OE1 3.4Å; I465-E469 PolarHBondContact O-N 2.9Å

Retrieved 469 of 469 residues in 346.7 ms (Link to these results)

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